Departments of Anesthesiology and Biostatistics | University of Michigan

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Scores Estradiol (pmol/L) Michigan Genomics Initiative Freeze 3 (MGI) PheWAS analysis

Estradiol (pmol/L) — Michigan Genomics Initiative Freeze 3 (MGI) PRS PheWAS

PRS model
PRS ID exprsweb-estradiol-oestradiol-30800-raw-dbslmm-mgi-freeze3-20211120Legacy DBSLMMDBSLMMUK Biobank GWAS

Evaluation cohort: Michigan Genomics Initiative Freeze 3 (MGI).

This page pairs the PheWAS plot with the full sortable table for the all-subject and exclusion scans.

Read the all-subject and exclusion scans separately. The combined view is only a browsing aid, and the selected-phecode panel below is only meaningful when the same phecode exists in both scans.

ExPRS exclusion definition

Exclusion cohort: study-defined normal-range subset.

For this ExPRS, the exclusion sensitivity scan keeps only the study-defined normal-range subset for Estradiol (pmol/L) before rerunning the PheWAS. The preserved release does not include numeric bounds for this trait. This is an exposure-based sensitivity analysis rather than a diagnosis-based exclusion.

Stratify by Sex and menopause state, 30 to 400 pg/mL for premenopausal women. 0 to 30 pg/mL for postmenopausal women. 10 to 50 pg/mL for men

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Plot overview

Signal overview

The plot gives a quick view of the currently visible associations. Click a point to pin its details, inspect that phecode across scans when both rows exist, or open the matching phecode detail page.

63 rows visible 16 categories
Phecode Description Category OR 95% CI P value Cases Controls Analysis Link
008 Intestinal infection Infectious Diseases 1.01 0.972 – 1.05 0.646 3004 29292 all phecode
008.5 Bacterial enteritis Infectious Diseases 1.04 0.985 – 1.1 0.15 1322 13162 all phecode
008.52 Intestinal infection due to C. difficile Infectious Diseases 1.05 0.985 – 1.12 0.141 1046 10455 all phecode
008.6 Viral Enteritis Infectious Diseases 0.977 0.908 – 1.05 0.547 770 7676 all phecode
010 Tuberculosis Infectious Diseases 0.997 0.873 – 1.14 0.968 244 2425 all phecode
031 Diseases due to other mycobacteria Infectious Diseases 0.859 0.674 – 1.09 0.217 86 855 all phecode
038 Septicemia Infectious Diseases 0.998 0.958 – 1.04 0.919 2582 24779 all phecode
038.1 Gram negative septicemia Infectious Diseases 1.05 0.964 – 1.14 0.281 568 5629 all phecode
038.2 Gram positive septicemia Infectious Diseases 0.898 0.776 – 1.04 0.146 235 2350 all phecode
038.3 Bacteremia Infectious Diseases 1.01 0.956 – 1.07 0.651 1210 12079 all phecode
041 Bacterial infection NOS Infectious Diseases 0.987 0.959 – 1.01 0.345 5750 38799 all phecode
041.1 Staphylococcus infections Infectious Diseases 0.987 0.938 – 1.04 0.606 1707 16977 all phecode
041.11 Methicillin sensitive Staphylococcus aureus Infectious Diseases 0.983 0.918 – 1.05 0.632 920 9192 all phecode
041.12 Methicillin resistant Staphylococcus aureus Infectious Diseases 0.999 0.929 – 1.08 0.986 783 7812 all phecode
041.2 Streptococcus infection Infectious Diseases 0.971 0.923 – 1.02 0.267 1632 16287 all phecode
041.21 Rheumatic fever / chorea Infectious Diseases 1.04 0.917 – 1.17 0.562 257 2554 all phecode
041.4 E. coli Infectious Diseases 0.973 0.917 – 1.03 0.375 1175 11680 all phecode
041.8 H. pylori Infectious Diseases 0.907 0.796 – 1.03 0.144 257 2521 all phecode
041.9 Infection with drug-resistant microorganisms Infectious Diseases 1.05 0.948 – 1.16 0.354 387 3864 all phecode
053 Herpes zoster Infectious Diseases 1 0.951 – 1.06 0.944 1560 15184 all phecode
053.1 Herpes zoster with nervous system complications Infectious Diseases 1.06 0.935 – 1.2 0.367 220 2169 all phecode
054 Herpes simplex Infectious Diseases 0.979 0.929 – 1.03 0.419 1593 15600 all phecode
070 Viral hepatitis Infectious Diseases 1.03 0.959 – 1.1 0.421 829 8280 all phecode
070.1 Viral hepatitis A Infectious Diseases 1.05 0.853 – 1.29 0.64 87 860 all phecode
070.2 Viral hepatitis B Infectious Diseases 1.06 0.928 – 1.21 0.387 215 2138 all phecode
070.3 Viral hepatitis C Infectious Diseases 1.01 0.92 – 1.1 0.897 528 5280 all phecode
070.4 Chronic hepatitis Infectious Diseases 1.03 0.891 – 1.19 0.688 197 1964 all phecode
070.9 Hepatitis NOS Infectious Diseases 1.03 0.973 – 1.1 0.286 1145 11381 all phecode
071 Human immunodeficiency virus [HIV] disease Infectious Diseases 0.994 0.835 – 1.18 0.946 145 1450 all phecode
071.1 HIV infection, symptomatic Infectious Diseases 0.983 0.815 – 1.19 0.862 117 1163 all phecode
078 Viral warts & HPV Infectious Diseases 1 0.965 – 1.04 0.996 3434 29624 all phecode
079 Viral infection Infectious Diseases 0.997 0.971 – 1.02 0.842 6664 35342 all phecode
079.1 Varicella infection Infectious Diseases 1 0.971 – 1.04 0.824 3793 31251 all phecode
079.2 Infectious mononucleosis Infectious Diseases 1.01 0.891 – 1.13 0.933 283 2723 all phecode
079.9 Viremia, NOS Infectious Diseases 0.993 0.924 – 1.07 0.838 838 8253 all phecode
080 Postoperative infection Infectious Diseases 0.982 0.943 – 1.02 0.383 2619 26065 all phecode
081
Infection/inflammation of internal prosthetic
Infection/inflammation of internal prosthetic device; implant; and graft
 Infectious Diseases 1 0.953 – 1.06 0.886 1589 15884 all phecode
090
Sexually transmitted infections (not HIV or
Sexually transmitted infections (not HIV or hepatitis)
 Infectious Diseases 1.02 0.955 – 1.09 0.572 965 9630 all phecode
110 Dermatophytosis / Dermatomycosis Infectious Diseases 0.996 0.961 – 1.03 0.818 3544 30054 all phecode
110.1 Dermatophytosis Infectious Diseases 0.999 0.963 – 1.04 0.937 3241 27244 all phecode
110.11 Dermatophytosis of nail Infectious Diseases 1 0.955 – 1.05 0.997 2044 16765 all phecode
110.12 Althete's foot Infectious Diseases 1.06 0.993 – 1.14 0.081 899 8043 all phecode
110.13 Dermatophytosis of the body Infectious Diseases 0.975 0.905 – 1.05 0.5 790 7827 all phecode
110.2 Dermatomycoses Infectious Diseases 0.977 0.879 – 1.09 0.663 398 3971 all phecode
112 Candidiasis Infectious Diseases 0.971 0.938 – 1.01 0.0966 3685 30495 all phecode
112.3 Candidiasis of skin and nails Infectious Diseases 1.04 0.96 – 1.12 0.369 682 6732 all phecode
117 Mycoses Infectious Diseases 1.01 0.928 – 1.09 0.868 608 6069 all phecode
117.1 Histoplasmosis Infectious Diseases 1.21 0.984 – 1.48 0.0718 81 801 all phecode
117.4 Aspergillosis Infectious Diseases 1.06 0.896 – 1.24 0.516 140 1387 all phecode
130 Spirochetal infection Infectious Diseases 1.02 0.864 – 1.19 0.856 168 1677 all phecode
130.1 Lyme disease Infectious Diseases 1.1 0.922 – 1.31 0.292 116 1160 all phecode
131 Protozoan infection Infectious Diseases 0.915 0.708 – 1.18 0.498 61 610 all phecode
132 Infestation (lice, mites) Infectious Diseases 1.11 0.965 – 1.28 0.146 195 1948 all phecode
134 Helminthiases Infectious Diseases 0.908 0.722 – 1.14 0.407 83 812 all phecode
134.1 Intestinal helminthiases Infectious Diseases 0.942 0.712 – 1.25 0.675 53 513 all phecode
136 Other infectious and parasitic diseases Infectious Diseases 1.01 0.973 – 1.04 0.661 3279 32486 all phecode
145 Cancer of mouth Neoplasms 0.982 0.93 – 1.04 0.499 1481 14725 all phecode
145.1 Cancer of lip Neoplasms 1.1 0.877 – 1.38 0.406 76 750 all phecode
145.2 Cancer of tongue Neoplasms 1.02 0.938 – 1.1 0.675 645 6430 all phecode
145.3 Cancer of major salivary glands Neoplasms 0.923 0.827 – 1.03 0.15 361 3597 all phecode
145.4 Cancer of the gums Neoplasms 0.976 0.826 – 1.15 0.774 166 1632 all phecode
145.5 Cancer of the mouth floor Neoplasms 1.01 0.872 – 1.16 0.921 206 2048 all phecode
149 Cancer of larynx, pharynx, nasal cavities Neoplasms 0.962 0.908 – 1.02 0.193 1290 12873 all phecode
149.1 Cancer of oropharynx Neoplasms 0.917 0.818 – 1.03 0.136 350 3499 all phecode
149.2 Cancer of nasopharynx Neoplasms 0.806 0.647 – 1 0.0546 100 1000 all phecode
149.3 Cancer of hypopharynx Neoplasms 1.01 0.805 – 1.27 0.926 82 819 all phecode
149.4 Cancer of larynx Neoplasms 1.03 0.932 – 1.14 0.536 386 3857 all phecode
149.5
Hx of malignant neoplasm of oral cavity and
Hx of malignant neoplasm of oral cavity and pharynx
 Neoplasms 0.957 0.876 – 1.05 0.33 552 5505 all phecode
149.9 Cancer of of nasal cavities Neoplasms 0.964 0.843 – 1.1 0.586 240 2398 all phecode
150 Cancer of esophagus Neoplasms 0.996 0.903 – 1.1 0.944 433 4315 all phecode
151 Cancer of stomach Neoplasms 1 0.914 – 1.1 0.954 498 4962 all phecode
153 Colorectal cancer Neoplasms 1.06 1.01 – 1.12 0.0241 1458 14383 all phecode
153.2 Colon cancer Neoplasms 1.06 0.998 – 1.12 0.0566 1160 11472 all phecode
153.3
Malignant neoplasm of rectum, rectosigmoid
Malignant neoplasm of rectum, rectosigmoid junction, and anus
 Neoplasms 1.04 0.974 – 1.12 0.222 815 8093 all phecode
155 Cancer of liver and intrahepatic bile duct Neoplasms 0.993 0.906 – 1.09 0.871 511 5097 all phecode
155.1 Malignant neoplasm of liver, primary Neoplasms 0.978 0.875 – 1.09 0.694 344 3433 all phecode
157 Pancreatic cancer Neoplasms 1.02 0.928 – 1.11 0.712 503 5005 all phecode
158
Neoplasm of unspecified nature of digestive
Neoplasm of unspecified nature of digestive system
 Neoplasms 1 0.954 – 1.06 0.904 1623 15759 all phecode
159
Malignant neoplasm of other and ill-defined
Malignant neoplasm of other and ill-defined sites within the digestive organs and peritoneum
 Neoplasms 1.01 0.96 – 1.06 0.756 1818 17869 all phecode
159.2
Malignant neoplasm of small intestine
Malignant neoplasm of small intestine, including duodenum
 Neoplasms 1.11 0.966 – 1.27 0.142 221 2206 all phecode
159.3
Malignant neoplasm of gallbladder and
Malignant neoplasm of gallbladder and extrahepatic bile ducts
 Neoplasms 1.04 0.883 – 1.22 0.66 158 1578 all phecode
159.4
Malignant neoplasm of retroperitoneum and
Malignant neoplasm of retroperitoneum and peritoneum
 Neoplasms 0.943 0.834 – 1.07 0.353 293 2920 all phecode
164 Cancer of intrathoracic organs Neoplasms 0.882 0.731 – 1.06 0.188 133 1324 all phecode
165 Cancer within the respiratory system Neoplasms 0.977 0.923 – 1.03 0.418 1336 13340 all phecode
165.1 Cancer of bronchus; lung Neoplasms 0.96 0.9 – 1.02 0.222 1057 10552 all phecode
170 Cancer of bone and connective tissue Neoplasms 0.98 0.933 – 1.03 0.422 1792 17850 all phecode
170.1 Bone cancer Neoplasms 0.992 0.921 – 1.07 0.824 773 7690 all phecode
170.2 Cancer of connective tissue Neoplasms 0.976 0.92 – 1.03 0.404 1266 12632 all phecode
172 Skin cancer Neoplasms 1 0.976 – 1.03 0.996 8608 33186 all phecode
172.1 Melanomas of skin, dx or hx Neoplasms 0.999 0.97 – 1.03 0.961 5330 30106 all phecode
172.11 Melanomas of skin Neoplasms 1 0.966 – 1.04 0.885 3100 25064 all phecode
172.2 Other non-epithelial cancer of skin Neoplasms 1 0.974 – 1.03 0.963 7095 30462 all phecode
172.21 Basal cell carcinoma Neoplasms 0.984 0.95 – 1.02 0.389 3690 23868 all phecode
172.22 Squamous cell carcinoma Neoplasms 1.01 0.969 – 1.06 0.597 2414 17683 all phecode
172.3 Carcinoma in situ of skin Neoplasms 1.01 0.955 – 1.06 0.79 1482 12326 all phecode
173 Neoplasm of uncertain behavior of skin Neoplasms 0.993 0.948 – 1.04 0.761 1997 18755 all phecode
174 Breast cancer Neoplasms 1.01 0.973 – 1.05 0.574 3186 15514 all phecode
174.1 Breast cancer [female] Neoplasms 1.01 0.975 – 1.05 0.496 3036 14701 all phecode
174.11 Malignant neoplasm of female breast Neoplasms 1.01 0.976 – 1.06 0.461 2991 14639 all phecode
174.3 Neoplasm of uncertain behavior of breast Neoplasms 1.11 0.975 – 1.26 0.115 233 2307 all phecode
175 Acquired absence of breast Neoplasms 0.998 0.933 – 1.07 0.959 919 8920 all phecode
180 Cervical cancer and dysplasia Neoplasms 0.967 0.914 – 1.02 0.234 1431 12185 all phecode
180.1 Cervical cancer Neoplasms 0.936 0.85 – 1.03 0.179 500 4982 all phecode
180.3
Cervical intraepithelial neoplasia [CIN]
Cervical intraepithelial neoplasia [CIN] [Cervical dysplasia]
 Neoplasms 0.986 0.925 – 1.05 0.672 1048 9323 all phecode
182 Malignant neoplasm of uterus Neoplasms 1.1 1.02 – 1.18 0.0106 765 7613 all phecode
184 Cancer of other female genital organs Neoplasms 1.05 0.986 – 1.11 0.136 1191 11592 all phecode
184.1
Malignant neoplasm of ovary and other uterine
Malignant neoplasm of ovary and other uterine adnexa
 Neoplasms 1 0.92 – 1.09 0.943 573 5719 all phecode
184.11 Malignant neoplasm of ovary Neoplasms 1.03 0.937 – 1.14 0.518 432 4309 all phecode
184.2
Cancer of other female genital organs
Cancer of other female genital organs (excluding uterus and ovary)
 Neoplasms 1.1 1.01 – 1.19 0.0218 608 6057 all phecode
185 Cancer of prostate Neoplasms 1.02 0.982 – 1.07 0.267 2901 10342 all phecode
187 Cancer of other male genital organs Neoplasms 0.981 0.877 – 1.1 0.744 339 3384 all phecode
187.1
Malignant neoplasm of unspecified male genital
Malignant neoplasm of unspecified male genital organ
 Neoplasms 0.957 0.776 – 1.18 0.683 115 1141 all phecode
187.2 Malignant neoplasm of testis Neoplasms 1.05 0.903 – 1.21 0.553 183 1830 all phecode
187.8
Neoplasm of uncertain behavior of male genital
Neoplasm of uncertain behavior of male genital organs
 Neoplasms 0.993 0.75 – 1.31 0.959 57 562 all phecode
189
Cancer of urinary organs (incl. kidney and
Cancer of urinary organs (incl. kidney and bladder)
 Neoplasms 0.986 0.949 – 1.03 0.485 2923 23541 all phecode
189.1 Cancer of kidney and renal pelvis Neoplasms 0.978 0.926 – 1.03 0.424 1450 14437 all phecode
189.11 Malignant neoplasm of kidney, except pelvis Neoplasms 0.978 0.923 – 1.04 0.448 1267 12655 all phecode
189.12 Malignant neoplasm of renal pelvis Neoplasms 1.05 0.928 – 1.2 0.418 237 2347 all phecode
189.2 Cancer of bladder Neoplasms 0.996 0.948 – 1.05 0.859 1783 15224 all phecode
189.21 Malignant neoplasm of bladder Neoplasms 0.996 0.947 – 1.05 0.87 1657 14178 all phecode
189.4 Malignant neoplasm of other urinary organs Neoplasms 1.02 0.947 – 1.11 0.546 678 6586 all phecode
190 Cancer of eye Neoplasms 1.12 0.958 – 1.31 0.154 138 1374 all phecode
191
Manlignant and unknown neoplasms of brain and
Manlignant and unknown neoplasms of brain and nervous system
 Neoplasms 0.973 0.913 – 1.04 0.405 1078 10771 all phecode
191.1 Cancer of brain and nervous system Neoplasms 0.981 0.907 – 1.06 0.621 706 7052 all phecode
191.11 Cancer of brain Neoplasms 0.992 0.912 – 1.08 0.848 600 5996 all phecode
193 Thyroid cancer Neoplasms 1.03 0.963 – 1.1 0.403 945 9393 all phecode
194 Cancer of other endocrine glands Neoplasms 0.936 0.858 – 1.02 0.138 579 5759 all phecode
195 Cancer, suspected or other Neoplasms 1.02 0.997 – 1.04 0.101 16962 26401 all phecode
195.1 Malignant neoplasm, other Neoplasms 1.02 0.996 – 1.04 0.119 16670 26384 all phecode
195.3 Malignant neoplasm of head, face, and neck Neoplasms 1.02 0.957 – 1.08 0.572 1103 9766 all phecode
196 Radiotherapy Neoplasms 0.994 0.953 – 1.04 0.797 2427 17006 all phecode
197 Chemotherapy Neoplasms 1 0.973 – 1.04 0.792 4952 23797 all phecode
198 Secondary malignant neoplasm Neoplasms 1.01 0.976 – 1.04 0.702 5801 23481 all phecode
198.1 Secondary malignancy of lymph nodes Neoplasms 1.01 0.971 – 1.04 0.734 3677 21489 all phecode
198.2 Secondary malignancy of respiratory organs Neoplasms 0.985 0.925 – 1.05 0.629 1072 10334 all phecode
198.3
Secondary malignant neoplasm of digestive
Secondary malignant neoplasm of digestive systems
 Neoplasms 1.05 0.982 – 1.12 0.148 866 8538 all phecode
198.4 Secondary malignant neoplasm of liver Neoplasms 1.04 0.964 – 1.11 0.336 767 7558 all phecode
198.5 Secondary malignancy of brain/spine Neoplasms 0.929 0.854 – 1.01 0.0905 640 6338 all phecode
198.6 Secondary malignancy of bone Neoplasms 0.963 0.897 – 1.03 0.294 866 8307 all phecode
198.7 Secondary malignant neoplasm of skin Neoplasms 0.943 0.841 – 1.06 0.314 336 3253 all phecode
199 Neoplasm of uncertain behavior Neoplasms 1.01 0.976 – 1.04 0.712 5693 25767 all phecode
199.4 Neurofibromatosis Neoplasms 1.07 0.868 – 1.32 0.518 88 880 all phecode
200 Myeloproliferative disease Neoplasms 0.942 0.883 – 1 0.0668 1113 11098 all phecode
200.1 Polycythemia vera Neoplasms 0.816 0.702 – 0.949 0.00829 231 2310 all phecode
201 Hodgkin's disease Neoplasms 1 0.859 – 1.17 0.957 172 1705 all phecode
202 Cancer of other lymphoid, histiocytic tissue Neoplasms 0.981 0.931 – 1.03 0.465 1559 15571 all phecode
202.2 Non-Hodgkins lymphoma Neoplasms 0.996 0.942 – 1.05 0.893 1329 13268 all phecode
202.21 Nodular lymphoma Neoplasms 0.98 0.907 – 1.06 0.612 693 6923 all phecode
202.22 Reticulosarcoma Neoplasms 1.03 0.879 – 1.21 0.722 170 1693 all phecode
202.24 Large cell lymphoma Neoplasms 1 0.852 – 1.18 0.965 160 1586 all phecode
204 Leukemia Neoplasms 0.97 0.896 – 1.05 0.443 689 6876 all phecode
204.1 Lymphoid leukemia Neoplasms 0.92 0.802 – 1.05 0.23 236 2354 all phecode
204.11 Lymphoid leukemia, acute Neoplasms 0.802 0.628 – 1.02 0.0768 74 734 all phecode
204.12 Lymphoid leukemia, chronic Neoplasms 0.963 0.822 – 1.13 0.638 173 1724 all phecode
204.2 Myeloid leukemia Neoplasms 0.982 0.866 – 1.11 0.783 265 2633 all phecode
204.21 Myeloid leukemia, acute Neoplasms 1.01 0.86 – 1.2 0.863 153 1516 all phecode
204.22 Myeloid leukemia, chronic Neoplasms 0.976 0.752 – 1.27 0.856 61 610 all phecode
204.4 Multiple myeloma Neoplasms 0.983 0.855 – 1.13 0.814 217 2162 all phecode
208 Benign neoplasm of colon Neoplasms 0.983 0.961 – 1.01 0.136 10303 34953 all phecode
209 Neuroendocrine tumors Neoplasms 1.06 0.942 – 1.2 0.321 258 2580 all phecode
210 Benign neoplasm of lip, oral cavity, and pharynx Neoplasms 0.968 0.922 – 1.02 0.187 1891 18839 all phecode
211
Benign neoplasm of other parts of digestive
Benign neoplasm of other parts of digestive system
 Neoplasms 0.998 0.973 – 1.02 0.874 7329 36606 all phecode
212
Benign neoplasm of respiratory and
Benign neoplasm of respiratory and intrathoracic organs
 Neoplasms 1 0.957 – 1.05 0.892 1843 18412 all phecode
213 Benign neoplasm of bone and articular cartilage Neoplasms 1.02 0.973 – 1.08 0.38 1677 15527 all phecode
214 Lipoma Neoplasms 1.02 0.964 – 1.07 0.533 1437 14132 all phecode
214.1 Lipoma of skin and subcutaneous tissue Neoplasms 1.02 0.954 – 1.09 0.555 883 8710 all phecode
215
Other benign neoplasm of connective and other
Other benign neoplasm of connective and other soft tissue
 Neoplasms 1.01 0.976 – 1.04 0.696 4528 39509 all phecode
216 Benign neoplasm of skin Neoplasms 0.999 0.978 – 1.02 0.949 11528 34919 all phecode
216.1 Screening for malignant neoplasms of the skin Neoplasms 0.979 0.841 – 1.14 0.784 174 1701 all phecode
217 Vascular hamartomas and non-neoplastic nevi Neoplasms 0.973 0.926 – 1.02 0.274 1786 17184 all phecode
217.1 Nevus, non-neoplastic Neoplasms 0.976 0.927 – 1.03 0.345 1679 16116 all phecode
218 Benign neoplasm of uterus Neoplasms 0.982 0.949 – 1.02 0.284 4301 16661 all phecode
218.1 Uterine leiomyoma Neoplasms 0.968 0.921 – 1.02 0.186 1835 15733 all phecode
218.2 Other benign neoplasm of uterus Neoplasms 0.988 0.952 – 1.03 0.531 3403 16447 all phecode
220 Benign neoplasm of ovary Neoplasms 0.945 0.881 – 1.01 0.119 893 8783 all phecode
221 Benign neoplasm of other female genital organs Neoplasms 0.992 0.947 – 1.04 0.726 2042 14248 all phecode
222 Benign neoplasm of male genital organs Neoplasms 1.03 0.967 – 1.09 0.383 1133 10663 all phecode
223
Benign neoplasm of kidney and other urinary
Benign neoplasm of kidney and other urinary organs
 Neoplasms 1.01 0.966 – 1.07 0.564 1801 12657 all phecode
224 Benign neoplasm of eye Neoplasms 0.971 0.897 – 1.05 0.456 691 6752 all phecode
224.1 Benign neoplasm of eye, uveal Neoplasms 0.956 0.878 – 1.04 0.308 595 5773 all phecode
225
Benign neoplasm of brain and other parts of
Benign neoplasm of brain and other parts of nervous system
 Neoplasms 0.979 0.923 – 1.04 0.481 1209 12074 all phecode
225.1
Benign neoplasm of brain, cranial nerves
Benign neoplasm of brain, cranial nerves, meninges
 Neoplasms 0.958 0.896 – 1.02 0.211 947 9454 all phecode
225.2 Benign neoplasm of spinal cord, meninges Neoplasms 1.07 0.948 – 1.2 0.289 289 2890 all phecode
226 Benign neoplasm of thyroid glands Neoplasms 1.03 0.976 – 1.09 0.269 1329 13264 all phecode
227
Benign neoplasm of other endocrine glands and
Benign neoplasm of other endocrine glands and related structures
 Neoplasms 1.03 0.977 – 1.08 0.307 1690 16896 all phecode
227.1 Benign neoplasm of adrenal gland Neoplasms 0.978 0.889 – 1.08 0.657 467 4644 all phecode
227.2 Benign neoplasm of parathyroid gland Neoplasms 1.05 0.981 – 1.13 0.155 795 7941 all phecode
227.3
Benign neoplasm of pituitary gland and
Benign neoplasm of pituitary gland and craniopharyngeal duct (pouch)
 Neoplasms 0.993 0.899 – 1.1 0.897 435 4350 all phecode
228 Hemangioma and lymphangioma, any site Neoplasms 0.991 0.948 – 1.04 0.692 2149 20946 all phecode
228.1 Hemangioma of skin and subcutaneous tissue Neoplasms 1 0.949 – 1.06 0.926 1356 13336 all phecode
229 Benign neoplasm of unspecified sites Neoplasms 1.01 0.989 – 1.04 0.293 7767 36615 all phecode
229.1 Benign neoplasm of lymph nodes Neoplasms 1.01 0.982 – 1.04 0.506 5743 34218 all phecode
240 Simple and unspecified goiter Endocrine/metabolic 1.01 0.944 – 1.07 0.876 1031 9761 all phecode
241 Nontoxic nodular goiter Endocrine/metabolic 1.01 0.973 – 1.05 0.577 2910 22227 all phecode
241.1 Nontoxic uninodular goiter Endocrine/metabolic 1.01 0.971 – 1.06 0.53 2265 19902 all phecode
241.2 Nontoxic multinodular goiter Endocrine/metabolic 1.05 0.998 – 1.11 0.0604 1304 12479 all phecode
242 Thyrotoxicosis with or without goiter Endocrine/metabolic 1.01 0.958 – 1.07 0.678 1400 13425 all phecode
242.1 Graves' disease Endocrine/metabolic 0.974 0.889 – 1.07 0.568 515 5068 all phecode
242.2 Toxic multinodular goiter Endocrine/metabolic 1.19 1.01 – 1.4 0.0364 124 1224 all phecode
242.3 Exophthalmos Endocrine/metabolic 1.04 0.928 – 1.17 0.481 292 2898 all phecode
242.31 Thyrotoxic exophthalmos Endocrine/metabolic 0.947 0.792 – 1.13 0.549 144 1432 all phecode
244 Hypothyroidism Endocrine/metabolic 0.979 0.955 – 1 0.101 8099 32717 all phecode
244.1 Secondary hypothyroidism Endocrine/metabolic 0.989 0.941 – 1.04 0.65 1762 17230 all phecode
244.2 Acquired hypothyroidism Endocrine/metabolic 0.969 0.914 – 1.03 0.283 1261 11982 all phecode
244.4 Hypothyroidism NOS Endocrine/metabolic 0.98 0.955 – 1.01 0.124 7542 32208 all phecode
245 Thyroiditis Endocrine/metabolic 0.99 0.922 – 1.06 0.791 832 7882 all phecode
245.2 Chronic thyroiditis Endocrine/metabolic 1 0.928 – 1.09 0.92 686 6517 all phecode
245.21 Chronic lymphocytic thyroiditis Endocrine/metabolic 1 0.926 – 1.09 0.949 679 6449 all phecode
246 Other disorders of thyroid Endocrine/metabolic 0.987 0.96 – 1.02 0.374 6129 30240 all phecode
246.2 Thyroid cyst Endocrine/metabolic 1.02 0.841 – 1.25 0.808 101 960 all phecode
246.7 Abnormal results of function study of thyroid Endocrine/metabolic 1.03 0.958 – 1.1 0.473 886 8696 all phecode
249 Secondary diabetes mellitus Endocrine/metabolic 1.01 0.946 – 1.08 0.728 1150 8340 all phecode
250 Diabetes mellitus Endocrine/metabolic 0.978 0.958 – 1 0.0481 13947 31815 all phecode
250.1 Type 1 diabetes Endocrine/metabolic 0.984 0.929 – 1.04 0.595 2364 11758 all phecode
250.11 Type 1 diabetes with ketoacidosis Endocrine/metabolic 1.06 0.902 – 1.25 0.477 262 960 all phecode
250.12 Type 1 diabetes with renal manifestations Endocrine/metabolic 1.04 0.933 – 1.16 0.467 551 2686 all phecode
250.13 Type 1 diabetes with ophthalmic manifestations Endocrine/metabolic 1.09 0.981 – 1.2 0.11 784 3018 all phecode
250.14 Type 1 diabetes with neurological manifestations Endocrine/metabolic 1.03 0.927 – 1.15 0.552 638 2675 all phecode
250.15
Diabetes type 1 with peripheral circulatory
Diabetes type 1 with peripheral circulatory disorders
 Endocrine/metabolic 1.02 0.849 – 1.24 0.801 155 850 all phecode
250.2 Type 2 diabetes Endocrine/metabolic 0.988 0.963 – 1.01 0.338 9843 29688 all phecode
250.21 Type 2 diabetes with ketoacidosis Endocrine/metabolic 1.02 0.875 – 1.19 0.802 282 1327 all phecode
250.22 Type 2 diabetes with renal manifestations Endocrine/metabolic 0.995 0.942 – 1.05 0.846 1941 13510 all phecode
250.23 Type 2 diabetes with ophthalmic manifestations Endocrine/metabolic 0.998 0.937 – 1.06 0.952 1643 9668 all phecode
250.24 Type 2 diabetes with neurological manifestations Endocrine/metabolic 1.01 0.965 – 1.06 0.605 2557 16502 all phecode
250.25
Diabetes type 2 with peripheral circulatory
Diabetes type 2 with peripheral circulatory disorders
 Endocrine/metabolic 0.989 0.913 – 1.07 0.791 860 6143 all phecode
250.3 Insulin pump user Endocrine/metabolic 1.01 0.964 – 1.05 0.766 3496 20809 all phecode
250.4 Abnormal glucose Endocrine/metabolic 0.968 0.942 – 0.994 0.0161 8385 30645 all phecode
250.41 Impaired fasting glucose Endocrine/metabolic 0.95 0.903 – 1 0.0508 1870 15861 all phecode
250.42 Other abnormal glucose Endocrine/metabolic 0.969 0.942 – 0.997 0.0299 7553 30071 all phecode
250.5 Glycosuria or Acetonuria Endocrine/metabolic 0.935 0.774 – 1.13 0.489 136 1067 all phecode
250.6 Polyneuropathy in diabetes Endocrine/metabolic 1 0.949 – 1.06 0.949 2132 13390 all phecode
250.7 Diabetic retinopathy Endocrine/metabolic 1 0.951 – 1.06 0.911 1691 10517 all phecode
251 Other disorders of pancreatic internal secretion Endocrine/metabolic 0.98 0.916 – 1.05 0.547 991 8469 all phecode
251.1 Hypoglycemia Endocrine/metabolic 0.969 0.904 – 1.04 0.375 1207 8570 all phecode
252 Disorders of parathyroid gland Endocrine/metabolic 1.04 0.996 – 1.08 0.0749 2282 22119 all phecode
252.1 Hyperparathyroidism Endocrine/metabolic 1.04 0.991 – 1.08 0.123 2088 20335 all phecode
252.2 Hypoparathyroidism Endocrine/metabolic 1.05 0.966 – 1.15 0.236 508 5073 all phecode
253
Disorders of the pituitary gland and its
Disorders of the pituitary gland and its hypothalamic control
 Endocrine/metabolic 0.954 0.888 – 1.02 0.191 859 8544 all phecode
253.1 Pituitary hyperfunction Endocrine/metabolic 1.01 0.89 – 1.14 0.935 263 2621 all phecode
253.11 Acromegaly and gigantism Endocrine/metabolic 1.09 0.879 – 1.36 0.421 83 826 all phecode
253.2 Pituitary hypofunction Endocrine/metabolic 0.977 0.85 – 1.12 0.74 226 2250 all phecode
253.3 Diabetes insipidus Endocrine/metabolic 0.902 0.72 – 1.13 0.368 86 860 all phecode
253.4 Anterior pituitary disorders Endocrine/metabolic 0.963 0.804 – 1.15 0.684 121 1209 all phecode
253.7 Other disorders of neurohypophysis Endocrine/metabolic 0.746 0.591 – 0.941 0.0133 108 1080 all phecode
255 Disorders of adrenal glands Endocrine/metabolic 1 0.952 – 1.06 0.916 1506 14869 all phecode
255.1 Adrenal hyperfunction Endocrine/metabolic 1.03 0.932 – 1.14 0.548 373 3730 all phecode
255.11 Cushing's syndrome Endocrine/metabolic 1.07 0.932 – 1.23 0.331 183 1830 all phecode
255.12 Hyperaldosteronism Endocrine/metabolic 0.991 0.837 – 1.17 0.917 135 1350 all phecode
255.2 Adrenal hypofunction Endocrine/metabolic 0.969 0.893 – 1.05 0.459 626 6239 all phecode
255.21 Glucocorticoid deficiency Endocrine/metabolic 0.988 0.909 – 1.07 0.78 596 5941 all phecode
256 Ovarian dysfunction Endocrine/metabolic 1.01 0.951 – 1.07 0.735 1146 10513 all phecode
256.4 Polycystic ovaries Endocrine/metabolic 1.02 0.944 – 1.1 0.652 742 7128 all phecode
257 Testicular dysfunction Endocrine/metabolic 0.962 0.9 – 1.03 0.252 1015 9238 all phecode
257.1 Testicular hypofunction Endocrine/metabolic 0.954 0.891 – 1.02 0.174 983 8933 all phecode
258 Iatrogenic endocrine disorders Endocrine/metabolic 0.998 0.815 – 1.22 0.987 91 910 all phecode
258.1 Postablative ovarian failure Endocrine/metabolic 1.09 0.906 – 1.32 0.351 109 1090 all phecode
259 Other endocrine disorders Endocrine/metabolic 0.959 0.9 – 1.02 0.206 1038 10259 all phecode
260 Protein-calorie malnutrition Endocrine/metabolic 0.994 0.956 – 1.03 0.759 2880 26812 all phecode
260.1 Cachexia Endocrine/metabolic 1.08 0.964 – 1.2 0.189 292 2911 all phecode
260.2 severe protein-calorie malnutrition Endocrine/metabolic 0.974 0.925 – 1.02 0.306 1691 16847 all phecode
260.22 Nutritional marasmus Endocrine/metabolic 0.998 0.921 – 1.08 0.962 614 6140 all phecode
260.3 Adult failure to thrive Endocrine/metabolic 1.05 0.969 – 1.13 0.243 629 6236 all phecode
260.6 Anorexia Endocrine/metabolic 0.973 0.906 – 1.04 0.441 868 8591 all phecode
260.7 Polyphagia Endocrine/metabolic 1.15 0.91 – 1.44 0.248 65 643 all phecode
261 Vitamin deficiency Endocrine/metabolic 0.981 0.957 – 1.01 0.144 7718 35203 all phecode
261.1 Vitamin A deficiency Endocrine/metabolic 1.06 0.838 – 1.33 0.644 69 690 all phecode
261.2 Vitamin B-complex deficiencies Endocrine/metabolic 0.988 0.921 – 1.06 0.733 857 8405 all phecode
261.4 Vitamin D deficiency Endocrine/metabolic 0.977 0.952 – 1 0.0819 7255 35225 all phecode
261.41 Rickets or osteomalacia Endocrine/metabolic 1.02 0.797 – 1.31 0.863 52 511 all phecode
262 Mineral deficiency NEC Endocrine/metabolic 0.971 0.914 – 1.03 0.348 1182 11676 all phecode
263 Other nutritional deficiency Endocrine/metabolic 1 0.956 – 1.06 0.847 1651 15788 all phecode
264 Lack of normal physiological development Endocrine/metabolic 0.923 0.808 – 1.05 0.239 239 2301 all phecode
264.2 Failure to thrive (childhood) Endocrine/metabolic 1.08 0.906 – 1.28 0.398 122 1220 all phecode
264.9
Lack of normal physiological development
Lack of normal physiological development, unspecified
 Endocrine/metabolic 0.883 0.699 – 1.12 0.298 81 772 all phecode
269 Proteinuria Endocrine/metabolic 0.993 0.944 – 1.04 0.781 1694 13981 all phecode
270
Disorders of protein plasma/amino-acid
Disorders of protein plasma/amino-acid transport and metabolism
 Endocrine/metabolic 1.05 0.981 – 1.11 0.169 967 9575 all phecode
270.1 Disturbances of amino-acid transport Endocrine/metabolic 1.05 0.911 – 1.22 0.481 170 1697 all phecode
270.11
Disturbances of sulphur-bearing amino-acid
Disturbances of sulphur-bearing amino-acid metabolism
 Endocrine/metabolic 1.02 0.862 – 1.21 0.816 134 1334 all phecode
270.2 Disorders of amino-acid metabolism Endocrine/metabolic 1.14 0.939 – 1.39 0.184 96 954 all phecode
270.3 Disorders of plasma protein metabolism Endocrine/metabolic 1.05 0.981 – 1.13 0.153 737 7303 all phecode
270.32 Paraproteinemia Endocrine/metabolic 1.02 0.923 – 1.12 0.712 384 3781 all phecode
270.33 Amyloidosis Endocrine/metabolic 1.2 0.96 – 1.51 0.108 71 695 all phecode
270.34 Alpha-1-antitrypsin deficiency Endocrine/metabolic 1.1 0.873 – 1.37 0.432 69 690 all phecode
270.38
Other specified disorders of plasma protein
Other specified disorders of plasma protein metabolism
 Endocrine/metabolic 1.07 0.951 – 1.2 0.267 299 2984 all phecode
271
Disorders of carbohydrate transport and
Disorders of carbohydrate transport and metabolism
 Endocrine/metabolic 0.985 0.947 – 1.02 0.428 2907 28132 all phecode
271.3
Intestinal disaccharidase deficiencies and
Intestinal disaccharidase deficiencies and disaccharide malabsorption
 Endocrine/metabolic 0.982 0.944 – 1.02 0.354 2827 27425 all phecode
271.9
Other disorders of carbohydrate transport and
Other disorders of carbohydrate transport and metabolism
 Endocrine/metabolic 1.1 0.913 – 1.32 0.323 102 1007 all phecode
272 Disorders of lipoid metabolism Endocrine/metabolic 0.989 0.969 – 1.01 0.292 18881 26670 all phecode
272.1 Hyperlipidemia Endocrine/metabolic 0.989 0.969 – 1.01 0.297 18843 26654 all phecode
272.11 Hypercholesterolemia Endocrine/metabolic 0.988 0.958 – 1.02 0.437 5928 21600 all phecode
272.12 Hyperglyceridemia Endocrine/metabolic 0.964 0.91 – 1.02 0.213 1360 11837 all phecode
272.13 Mixed hyperlipidemia Endocrine/metabolic 0.991 0.953 – 1.03 0.646 3538 18449 all phecode
272.9 Unspecified disorder of lipoid metabolism Endocrine/metabolic 0.978 0.869 – 1.1 0.706 313 3011 all phecode
274 Gout and other crystal arthropathies Endocrine/metabolic 0.993 0.953 – 1.03 0.726 2524 22729 all phecode
274.1 Gout Endocrine/metabolic 0.994 0.953 – 1.04 0.768 2409 21991 all phecode
274.11 Gouty arthropathy Endocrine/metabolic 1.01 0.946 – 1.07 0.826 1082 10576 all phecode
274.2 Crystal arthropathies Endocrine/metabolic 0.986 0.854 – 1.14 0.845 195 1890 all phecode
274.21 Chondrocalcinosis Endocrine/metabolic 0.98 0.842 – 1.14 0.79 183 1772 all phecode
275 Disorders of mineral metabolism Endocrine/metabolic 0.968 0.938 – 1 0.0487 4357 37091 all phecode
275.1 Disorders of iron metabolism Hematopoietic 0.964 0.84 – 1.11 0.597 218 2180 all phecode
275.11 Hereditary hemochromatosis Hematopoietic 0.953 0.774 – 1.17 0.65 99 990 all phecode
275.2 Disorders of copper metabolism Endocrine/metabolic 0.906 0.696 – 1.18 0.461 62 614 all phecode
275.3 Disorders of magnesium metabolism Endocrine/metabolic 0.961 0.904 – 1.02 0.209 1154 11504 all phecode
275.5 Disorders of calcium/phosphorus metabolism Endocrine/metabolic 0.974 0.94 – 1.01 0.152 3369 31544 all phecode
275.51 Hypocalcemia Endocrine/metabolic 0.963 0.898 – 1.03 0.294 898 8969 all phecode
275.53 Disorders of phosphorus metabolism Endocrine/metabolic 0.977 0.922 – 1.03 0.417 1366 13634 all phecode
275.6 Hypercalcemia Endocrine/metabolic 0.974 0.923 – 1.03 0.349 1468 14183 all phecode
276
Disorders of fluid, electrolyte, and acid-base
Disorders of fluid, electrolyte, and acid-base balance
 Endocrine/metabolic 0.986 0.963 – 1.01 0.227 9238 37046 all phecode
276.1 Electrolyte imbalance Endocrine/metabolic 0.993 0.967 – 1.02 0.631 6352 34366 all phecode
276.11 Hyperosmolality and/or hypernatremia Endocrine/metabolic 0.984 0.901 – 1.07 0.715 550 5434 all phecode
276.12 Hyposmolality and/or hyponatremia Endocrine/metabolic 0.998 0.958 – 1.04 0.928 2514 23219 all phecode
276.13 Hyperpotassemia Endocrine/metabolic 1.01 0.97 – 1.05 0.695 2992 25216 all phecode
276.14 Hypopotassemia Endocrine/metabolic 0.977 0.934 – 1.02 0.307 2148 20909 all phecode
276.4 Acid-base balance disorder Endocrine/metabolic 1.02 0.977 – 1.07 0.34 2086 20332 all phecode
276.41 Acidosis Endocrine/metabolic 1.02 0.972 – 1.07 0.423 1788 17572 all phecode
276.42 Alkalosis Endocrine/metabolic 1 0.912 – 1.1 0.991 476 4741 all phecode
276.5 Hypovolemia Endocrine/metabolic 0.969 0.939 – 1 0.0469 4574 34527 all phecode
276.6 Fluid overload Endocrine/metabolic 1.01 0.956 – 1.07 0.742 1384 13211 all phecode
276.8 Polydipsia Endocrine/metabolic 1.03 0.856 – 1.23 0.775 124 1240 all phecode
277 Other disorders of metabolism Endocrine/metabolic 0.989 0.957 – 1.02 0.508 4112 35070 all phecode
277.2
Other disorders of purine and pyrimidine
Other disorders of purine and pyrimidine metabolism
 Endocrine/metabolic 0.941 0.849 – 1.04 0.25 403 3991 all phecode
277.4 Disorders of bilirubin excretion Endocrine/metabolic 0.962 0.89 – 1.04 0.32 720 7161 all phecode
277.5 Other disorders of lipoid metabolism Endocrine/metabolic 1.01 0.951 – 1.08 0.658 936 9270 all phecode
277.51 Lipoprotein disorders Endocrine/metabolic 0.994 0.924 – 1.07 0.865 773 7668 all phecode
277.7 Dysmetabolic syndrome X Endocrine/metabolic 0.987 0.922 – 1.06 0.711 916 8359 all phecode
278 Overweight, obesity and other hyperalimentation Endocrine/metabolic 1 0.985 – 1.02 0.73 19419 27331 all phecode
278.1 Obesity Endocrine/metabolic 1 0.983 – 1.02 0.784 17129 27321 all phecode
278.11 Morbid obesity Endocrine/metabolic 1.01 0.982 – 1.03 0.6 8280 27172 all phecode
278.3 Localized adiposity Endocrine/metabolic 0.87 0.77 – 0.984 0.0269 324 3228 all phecode
278.4 Abnormal weight gain Endocrine/metabolic 0.977 0.933 – 1.02 0.325 2104 17411 all phecode
279 Disorders involving the immune mechanism Endocrine/metabolic 1.01 0.977 – 1.05 0.463 2934 28612 all phecode
279.1 Immunity deficiency Endocrine/metabolic 1 0.942 – 1.06 0.992 1161 11571 all phecode
279.11 Deficiency of humoral immunity Endocrine/metabolic 1.06 0.953 – 1.18 0.278 330 3278 all phecode
279.2 Autoimmune disease NEC Endocrine/metabolic 0.934 0.865 – 1.01 0.0865 754 7516 all phecode
279.7 Other immunological findings Endocrine/metabolic 1.03 0.995 – 1.06 0.099 4885 36552 all phecode
279.8
Other specified disorders involving the immune
Other specified disorders involving the immune mechanism
 Endocrine/metabolic 0.934 0.858 – 1.02 0.119 601 5988 all phecode
280 Iron deficiency anemias Hematopoietic 0.983 0.953 – 1.01 0.295 4626 30873 all phecode
280.1
Iron deficiency anemias, unspecified or not due
Iron deficiency anemias, unspecified or not due to blood loss
 Hematopoietic 0.983 0.952 – 1.01 0.281 4484 30649 all phecode
280.2
Iron deficiency anemia secondary to blood loss
Iron deficiency anemia secondary to blood loss (chronic)
 Hematopoietic 0.991 0.944 – 1.04 0.723 1771 17196 all phecode
281 Other deficiency anemia Hematopoietic 1 0.918 – 1.09 0.967 519 5120 all phecode
281.1 Megaloblastic anemia Hematopoietic 0.85 0.74 – 0.977 0.0219 253 2497 all phecode
281.11 Pernicious anemia Hematopoietic 0.614 0.479 – 0.786 0.000109 114 1108 all phecode
281.12 Other vitamin B12 deficiency anemia Hematopoietic 0.785 0.664 – 0.929 0.00481 187 1817 all phecode
281.9 Deficiency anemias Hematopoietic 1.1 0.987 – 1.23 0.0861 285 2830 all phecode
282 Hereditary hemolytic anemias Hematopoietic 1 0.897 – 1.12 0.953 323 3188 all phecode
282.8 Other hemoglobinopathies Hematopoietic 1.04 0.915 – 1.19 0.522 216 2113 all phecode
282.9 Other hereditary hemolytic anemias Hematopoietic 0.973 0.836 – 1.13 0.729 192 1920 all phecode
283 Acquired hemolytic anemias Hematopoietic 1.11 0.943 – 1.3 0.212 155 1550 all phecode
283.1 Autoimmune hemolytic anemias Hematopoietic 0.924 0.711 – 1.2 0.554 64 633 all phecode
284 Aplastic anemia Hematopoietic 0.956 0.882 – 1.04 0.27 697 6943 all phecode
284.1 Pancytopenia Hematopoietic 0.972 0.894 – 1.06 0.499 612 6100 all phecode
285 Other anemias Hematopoietic 0.986 0.966 – 1.01 0.211 11794 33591 all phecode
285.1 Acute posthemorrhagic anemia Hematopoietic 1 0.966 – 1.04 0.914 3325 27709 all phecode
285.2 Anemia of chronic disease Hematopoietic 0.987 0.943 – 1.03 0.575 2055 19939 all phecode
285.21 Anemia in chronic kidney disease Hematopoietic 0.96 0.896 – 1.03 0.244 932 9106 all phecode
285.22 Anemia in neoplastic disease Hematopoietic 1.04 0.961 – 1.12 0.356 690 6892 all phecode
286 Coagulation defects Hematopoietic 0.996 0.963 – 1.03 0.822 3844 33384 all phecode
286.1 Congenital coagulation defects Hematopoietic 0.927 0.811 – 1.06 0.264 250 2466 all phecode
286.11 Von willebrand's disease Hematopoietic 0.931 0.735 – 1.18 0.556 83 822 all phecode
286.12
Congenital deficiency of other clotting factors
Congenital deficiency of other clotting factors (including factor VII)
 Hematopoietic 0.946 0.786 – 1.14 0.554 126 1260 all phecode
286.2
Encounter for long-term (current) use of
Encounter for long-term (current) use of anticoagulants
 Hematopoietic 0.989 0.954 – 1.03 0.55 3354 25918 all phecode
286.3
Coagulation defects complicating pregnancy or
Coagulation defects complicating pregnancy or postpartum
 Hematopoietic 1.13 0.932 – 1.37 0.212 97 962 all phecode
286.4 Acquired coagulation factor deficiency Hematopoietic 0.85 0.737 – 0.981 0.0262 254 2529 all phecode
286.5
Hemorrhagic disorder due to intrinsic
Hemorrhagic disorder due to intrinsic circulating anticoagulants
 Hematopoietic 0.873 0.724 – 1.05 0.157 132 1294 all phecode
286.6 Defibrination syndrome Hematopoietic 0.987 0.947 – 1.03 0.515 2579 25377 all phecode
286.7 Other and unspecified coagulation defects Hematopoietic 0.984 0.947 – 1.02 0.395 3014 29294 all phecode
286.8 Hypercoagulable state Hematopoietic 0.981 0.913 – 1.05 0.599 846 8437 all phecode
286.81 Primary hypercoagulable state Hematopoietic 0.978 0.908 – 1.05 0.551 813 8111 all phecode
286.9 Abnormal coagulation profile Hematopoietic 1.01 0.949 – 1.07 0.83 1182 11487 all phecode
287 Purpura and other hemorrhagic conditions Hematopoietic 1 0.967 – 1.04 0.883 3288 28474 all phecode
287.1 Spontaneous ecchymoses Hematopoietic 1.04 0.912 – 1.19 0.542 211 2094 all phecode
287.3 Thrombocytopenia Hematopoietic 0.999 0.962 – 1.04 0.964 2938 26323 all phecode
287.31 Primary thrombocytopenia Hematopoietic 0.952 0.874 – 1.04 0.254 601 5994 all phecode
287.32 Secondary thrombocytopenia Hematopoietic 0.994 0.913 – 1.08 0.894 569 5686 all phecode
287.4 Qualitative platelet defects Hematopoietic 0.984 0.815 – 1.19 0.87 112 1120 all phecode
288 Diseases of white blood cells Hematopoietic 1 0.975 – 1.04 0.747 4886 36527 all phecode
288.1 Decreased white blood cell count Hematopoietic 0.989 0.939 – 1.04 0.674 1599 15951 all phecode
288.11 Neutropenia Hematopoietic 0.972 0.913 – 1.03 0.373 1106 11041 all phecode
288.2 Elevated white blood cell count Hematopoietic 1.01 0.98 – 1.05 0.463 4082 35079 all phecode
288.3 Eosinophilia Hematopoietic 1 0.866 – 1.17 0.949 187 1866 all phecode
289 Other diseases of blood and blood-forming organs Hematopoietic 0.968 0.921 – 1.02 0.192 1757 17434 all phecode
289.3
Personal history of diseases of blood and
Personal history of diseases of blood and blood-forming organs
 Hematopoietic 0.933 0.871 – 1 0.0505 918 9087 all phecode
289.4 Lymphadenitis Hematopoietic 0.985 0.952 – 1.02 0.369 3888 34715 all phecode
289.5 Diseases of spleen Hematopoietic 0.875 0.784 – 0.978 0.0184 393 3913 all phecode
289.8 Polycythemia, secondary Hematopoietic 0.916 0.8 – 1.05 0.201 255 2550 all phecode
289.9 Abnormality of red blood cells Hematopoietic 1.02 0.924 – 1.14 0.642 385 3813 all phecode
290
Delirium dementia and amnestic and other
Delirium dementia and amnestic and other cognitive disorders
 Mental Disorders 0.995 0.94 – 1.05 0.862 1318 11547 all phecode
290.1 Dementias Mental Disorders 1 0.916 – 1.09 0.976 541 4910 all phecode
290.11 Alzheimer's disease Mental Disorders 0.928 0.781 – 1.1 0.397 151 1389 all phecode
290.12 Dementia with cerebral degenerations Mental Disorders 0.986 0.791 – 1.23 0.903 88 846 all phecode
290.13 Senile dementia Mental Disorders 0.965 0.862 – 1.08 0.54 340 3078 all phecode
290.16 Vascular dementia Mental Disorders 1.16 0.929 – 1.44 0.193 81 777 all phecode
290.2 Delirium due to conditions classified elsewhere Mental Disorders 0.997 0.924 – 1.08 0.935 750 7358 all phecode
290.3
Other persistent mental disorders due to
Other persistent mental disorders due to conditions classified elsewhere
 Mental Disorders 0.971 0.906 – 1.04 0.417 886 8618 all phecode
291
Other specified nonpsychotic and/or transient
Other specified nonpsychotic and/or transient mental disorders
 Mental Disorders 1.04 1 – 1.09 0.0308 2550 24810 all phecode
291.1
Transient mental disorders due to conditions
Transient mental disorders due to conditions classified elsewhere
 Mental Disorders 1.07 0.922 – 1.24 0.375 175 1750 all phecode
291.4
Specific nonpsychotic mental disorders due to
Specific nonpsychotic mental disorders due to brain damage
 Mental Disorders 0.981 0.894 – 1.08 0.688 484 4807 all phecode
291.8 Alteration of consciousness Mental Disorders 1.04 0.998 – 1.09 0.0617 2036 19974 all phecode
292 Neurological disorders Mental Disorders 0.999 0.972 – 1.03 0.965 5733 38553 all phecode
292.1 Aphasia/speech disturbance Mental Disorders 1.01 0.968 – 1.06 0.57 2013 19867 all phecode
292.11 Aphasia Mental Disorders 1.02 0.942 – 1.1 0.628 664 6581 all phecode
292.12 Symbolic dysfunction Mental Disorders 1.09 0.957 – 1.25 0.186 200 1988 all phecode
292.2 Mild cognitive impairment Mental Disorders 1.1 0.992 – 1.21 0.0708 389 3731 all phecode
292.3 Memory loss Mental Disorders 0.995 0.949 – 1.04 0.841 1922 18158 all phecode
292.4 Altered mental status Mental Disorders 1.02 0.975 – 1.06 0.453 2454 22725 all phecode
292.5 Transient alteration of awareness Mental Disorders 1.09 0.989 – 1.2 0.0849 430 4285 all phecode
292.6 Hallucinations Mental Disorders 1.04 0.911 – 1.19 0.558 217 2147 all phecode
293 Symptoms involving head and neck Mental Disorders 1.05 0.957 – 1.16 0.291 414 4127 all phecode
293.1
Swelling, mass, or lump in head and neck
Swelling, mass, or lump in head and neck [Space-occupying lesion, intracranial NOS]
 Mental Disorders 1.02 0.988 – 1.05 0.225 4417 38609 all phecode
295 Schizophrenia and other psychotic disorders Mental Disorders 1.01 0.945 – 1.08 0.753 885 8229 all phecode
295.1 Schizophrenia Mental Disorders 0.936 0.781 – 1.12 0.476 138 1339 all phecode
295.2 Paranoid disorders Mental Disorders 0.961 0.799 – 1.15 0.67 118 1079 all phecode
295.3 Psychosis Mental Disorders 1.07 0.998 – 1.15 0.0568 716 6694 all phecode
296 Mood disorders Mental Disorders 0.994 0.973 – 1.02 0.586 15356 20858 all phecode
296.1 Bipolar Mental Disorders 0.979 0.924 – 1.04 0.47 1301 11264 all phecode
296.2 Depression Mental Disorders 0.993 0.972 – 1.01 0.51 14833 20856 all phecode
296.22 Major depressive disorder Mental Disorders 0.996 0.974 – 1.02 0.697 13850 20853 all phecode
297 Suicidal ideation or attempt Mental Disorders 0.973 0.909 – 1.04 0.428 985 9050 all phecode
297.1 Suicidal ideation Mental Disorders 0.948 0.878 – 1.02 0.172 788 7310 all phecode
297.2 Suicide or self-inflicted injury Mental Disorders 1 0.884 – 1.14 0.975 285 2654 all phecode
300 Anxiety disorders Mental Disorders 0.991 0.97 – 1.01 0.388 15419 20850 all phecode
300.1 Anxiety disorder Mental Disorders 0.991 0.97 – 1.01 0.434 14517 20855 all phecode
300.11 Generalized anxiety disorder Mental Disorders 0.984 0.954 – 1.02 0.316 5546 20512 all phecode
300.12 Agorophobia, social phobia, and panic disorder Mental Disorders 1.02 0.965 – 1.08 0.453 1360 11377 all phecode
300.13 Phobia Mental Disorders 0.957 0.895 – 1.02 0.2 1051 9542 all phecode
300.3 Obsessive-compulsive disorders Mental Disorders 0.973 0.867 – 1.09 0.64 328 3018 all phecode
300.4 Dysthymic disorder Mental Disorders 0.978 0.937 – 1.02 0.321 2420 16552 all phecode
300.8 Acute reaction to stress Mental Disorders 1.05 0.957 – 1.14 0.32 504 4825 all phecode
300.9 Posttraumatic stress disorder Mental Disorders 0.991 0.922 – 1.07 0.816 843 7909 all phecode
301 Personality disorders Mental Disorders 0.975 0.886 – 1.07 0.603 477 4539 all phecode
301.2 Antisocial/borderline personality disorder Mental Disorders 0.948 0.83 – 1.08 0.429 254 2393 all phecode
302 Sexual and gender identity disorders Mental Disorders 1.01 0.971 – 1.05 0.685 3700 13808 all phecode
302.1 Decreased libido Mental Disorders 1.06 0.964 – 1.17 0.232 447 4331 all phecode
303 Psychogenic and somatoform disorders Mental Disorders 0.997 0.97 – 1.03 0.844 6808 20043 all phecode
303.1 Dissociative disorder Mental Disorders 1.12 0.963 – 1.31 0.139 161 1573 all phecode
303.3 Psychogenic disorder Mental Disorders 1 0.973 – 1.03 0.934 6487 19888 all phecode
303.31
Gastrointestinal malfunction arising from
Gastrointestinal malfunction arising from mental factors
 Mental Disorders 1.03 0.938 – 1.13 0.562 471 4623 all phecode
303.4 Somatoform disorder Mental Disorders 0.971 0.914 – 1.03 0.332 1177 11180 all phecode
304 Adjustment reaction Mental Disorders 1 0.966 – 1.03 0.985 3888 20475 all phecode
305.2 Eating disorder Mental Disorders 0.975 0.909 – 1.05 0.476 901 8329 all phecode
306 Other mental disorder Mental Disorders 0.95 0.903 – 0.999 0.0453 1815 14133 all phecode
306.1 Mental disorders durring/after pregnancy Mental Disorders 1.05 0.964 – 1.15 0.255 587 3527 all phecode
306.9 Tension headache Mental Disorders 0.937 0.866 – 1.01 0.0991 753 7277 all phecode
312 Conduct disorders Mental Disorders 0.953 0.837 – 1.09 0.469 254 2501 all phecode
312.3 Impulse control disorder Mental Disorders 1.04 0.824 – 1.32 0.733 74 736 all phecode
313 Pervasive developmental disorders Mental Disorders 1 0.949 – 1.05 0.996 1571 14633 all phecode
313.1 Attention deficit hyperactivity disorder Mental Disorders 1.01 0.959 – 1.07 0.647 1392 13190 all phecode
313.2 Tics and stuttering Mental Disorders 0.864 0.679 – 1.1 0.236 77 770 all phecode
313.3 Autism Mental Disorders 1.15 0.908 – 1.44 0.253 64 621 all phecode
315 Develomental delays and disorders Mental Disorders 0.971 0.896 – 1.05 0.465 684 6788 all phecode
315.1 Learning disorder Mental Disorders 0.825 0.649 – 1.05 0.115 87 860 all phecode
315.2 Speech and language disorder Mental Disorders 0.956 0.84 – 1.09 0.5 254 2539 all phecode
316 Substance addiction and disorders Mental Disorders 0.994 0.961 – 1.03 0.733 3682 32680 all phecode
316.1 Polyneuropathy due to drugs Mental Disorders 1.02 0.942 – 1.11 0.622 634 6331 all phecode
317 Alcohol-related disorders Mental Disorders 0.983 0.943 – 1.03 0.433 2525 22920 all phecode
317.1 Alcoholism Mental Disorders 1.01 0.959 – 1.05 0.822 1986 19339 all phecode
317.11 Alcoholic liver damage Mental Disorders 0.972 0.878 – 1.08 0.578 408 4080 all phecode
318 Tobacco use disorder Mental Disorders 0.983 0.96 – 1.01 0.169 8622 34842 all phecode
320 Meningitis Neurological 1.04 0.94 – 1.15 0.439 382 3820 all phecode
323 Encephalitis Neurological 1.09 0.943 – 1.27 0.236 181 1809 all phecode
323.8 Encephalitis, non-infectious Neurological 1.08 0.921 – 1.26 0.347 153 1527 all phecode
324 Other CNS infection and poliomyelitis Neurological 1.08 0.959 – 1.21 0.207 288 2880 all phecode
325
Phlebitis and thrombophlebitis of intracranial
Phlebitis and thrombophlebitis of intracranial venous sinuses
 Neurological 1.01 0.782 – 1.3 0.959 53 530 all phecode
327 Sleep disorders Neurological 0.997 0.978 – 1.02 0.796 14941 31602 all phecode
327.1 Hypersomnia Neurological 0.983 0.939 – 1.03 0.473 2061 19110 all phecode
327.3 Sleep apnea Neurological 0.999 0.977 – 1.02 0.949 10909 31304 all phecode
327.31 Central/nonobstroctive sleep apnea Neurological 1 0.911 – 1.1 0.976 492 4784 all phecode
327.32 Obstructive sleep apnea Neurological 0.996 0.972 – 1.02 0.753 8744 30530 all phecode
327.4 Insomnia Neurological 0.986 0.958 – 1.02 0.35 5524 30960 all phecode
327.41 Organic or persistent insomnia Neurological 0.988 0.932 – 1.05 0.679 1265 12120 all phecode
327.5 Parasomnia Neurological 1.05 0.967 – 1.14 0.251 604 5913 all phecode
327.6 Circadian rhythm sleep disorder Neurological 0.919 0.808 – 1.05 0.203 274 2666 all phecode
327.7 Sleep related movement disorders Neurological 1.01 0.963 – 1.06 0.648 1786 17323 all phecode
327.71 Restless legs syndrome Neurological 1.01 0.959 – 1.06 0.698 1570 15360 all phecode
327.72 Sleep related leg cramps Neurological 1.08 0.881 – 1.33 0.455 83 822 all phecode
331 Other cerebral degenerations Neurological 0.987 0.913 – 1.07 0.735 717 7024 all phecode
331.1 Hydrocephalus Neurological 0.969 0.855 – 1.1 0.615 284 2836 all phecode
331.9 Cerebral degeneration, unspecified Neurological 1 0.904 – 1.11 0.994 419 4026 all phecode
332 Parkinson's disease Neurological 0.925 0.832 – 1.03 0.149 415 4128 all phecode
333
Extrapyramidal disease and abnormal movement
Extrapyramidal disease and abnormal movement disorders
 Neurological 0.985 0.948 – 1.02 0.441 2868 26583 all phecode
333.1 Essential tremor Neurological 0.98 0.907 – 1.06 0.617 725 7163 all phecode
333.2 Myoclonus Neurological 0.898 0.75 – 1.08 0.243 159 1590 all phecode
333.4 Torsion dystonia Neurological 1.02 0.918 – 1.13 0.738 352 3504 all phecode
333.8 Other degenerative diseases of the basal ganglia Neurological 1.21 0.989 – 1.49 0.064 89 890 all phecode
334 Degenerative disease of the spinal cord Neurological 1.02 0.958 – 1.09 0.537 1058 10562 all phecode
334.1 Spinocerebellar disease Neurological 1.01 0.808 – 1.27 0.901 79 790 all phecode
334.2 Anterior horn cell disease Neurological 1.1 0.905 – 1.33 0.347 110 1080 all phecode
334.21 Amyotrophic Lateral Sclerosis Neurological 1.21 0.958 – 1.52 0.11 71 693 all phecode
335 Multiple sclerosis Neurological 0.974 0.879 – 1.08 0.611 396 3951 all phecode
337 Disorders of the autonomic nervous system Neurological 1.01 0.942 – 1.09 0.763 808 7413 all phecode
337.1 Peripheral autonomic neuropathy Neurological 1.05 0.944 – 1.16 0.395 370 3164 all phecode
338 Pain Neurological 0.985 0.967 – 1 0.107 20346 26417 all phecode
338.1 Acute pain Neurological 0.98 0.96 – 1 0.0463 15582 26313 all phecode
338.2 Chronic pain Neurological 0.988 0.967 – 1.01 0.307 10994 26368 all phecode
339 Other headache syndromes Neurological 0.975 0.952 – 0.998 0.033 9242 34658 all phecode
340 Migraine Neurological 0.984 0.958 – 1.01 0.247 6708 30587 all phecode
340.1 Migrain with aura Neurological 0.971 0.937 – 1.01 0.105 3624 23684 all phecode
341
Other demyelinating diseases of central nervous
Other demyelinating diseases of central nervous system
 Neurological 1.06 0.896 – 1.25 0.497 133 1330 all phecode
342 Hemiplegia Neurological 0.997 0.908 – 1.09 0.948 464 4607 all phecode
343 Infantile cerebral palsy Neurological 0.948 0.753 – 1.19 0.653 85 847 all phecode
344 Other paralytic syndromes Neurological 0.984 0.909 – 1.07 0.691 682 6808 all phecode
345 Epilepsy, recurrent seizures, convulsions Neurological 1.01 0.965 – 1.05 0.805 2553 25307 all phecode
345.1 Epilepsy Neurological 1.01 0.939 – 1.09 0.774 747 7465 all phecode
345.11 Generalized convulsive epilepsy Neurological 0.987 0.867 – 1.12 0.85 233 2330 all phecode
345.12 Partial epilepsy Neurological 1.01 0.923 – 1.1 0.865 534 5335 all phecode
345.3 Convulsions Neurological 1.01 0.965 – 1.05 0.79 2396 23796 all phecode
346
Abnormal findings on study of brain and/or
Abnormal findings on study of brain and/or nervous system
 Neurological 0.908 0.776 – 1.06 0.227 183 1824 all phecode
346.1
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of skull and head
 Neurological 0.963 0.912 – 1.02 0.18 1472 14587 all phecode
346.2
Nonspecific abnormal results of function study
Nonspecific abnormal results of function study of brain and central nervous system
 Neurological 0.951 0.785 – 1.15 0.605 120 1181 all phecode
346.3
Nonspecific abnormal findings in cerebrospinal
Nonspecific abnormal findings in cerebrospinal fluid
 Neurological 1.12 0.932 – 1.34 0.232 110 1100 all phecode
347 Cataplexy and narcolepsy Neurological 1.02 0.832 – 1.26 0.829 101 1010 all phecode
348 Other conditions of brain Neurological 1 0.957 – 1.05 0.843 1793 17894 all phecode
348.2 Cerebral edema and compression of brain Neurological 0.986 0.921 – 1.06 0.689 905 9034 all phecode
348.4 Cerebral cysts Neurological 1.07 0.941 – 1.22 0.301 229 2290 all phecode
348.7 Coma Neurological 1.14 1 – 1.3 0.045 229 2275 all phecode
348.8 Encephalopathy, not elsewhere classified Neurological 1.01 0.94 – 1.08 0.824 853 8479 all phecode
348.9 Other conditions of brain, NOS Neurological 1.01 0.967 – 1.05 0.688 2341 23287 all phecode
349
Other and unspecified disorders of the nervous
Other and unspecified disorders of the nervous system
 Neurological 1.03 0.963 – 1.1 0.409 941 9385 all phecode
350 Abnormal movement Neurological 1 0.974 – 1.03 0.985 6706 38762 all phecode
350.1 Abnormal involuntary movements Neurological 1.01 0.97 – 1.04 0.754 3273 30524 all phecode
350.2 Abnormality of gait Neurological 0.991 0.958 – 1.02 0.603 3920 30520 all phecode
350.3 Lack of coordination Neurological 0.982 0.921 – 1.05 0.575 1062 10554 all phecode
350.5 Abnormal reflex Neurological 0.93 0.799 – 1.08 0.343 200 1988 all phecode
350.6 Disturbances of sensation of smell and taste Neurological 0.965 0.884 – 1.05 0.424 558 5576 all phecode
351 Other peripheral nerve disorders Neurological 0.988 0.963 – 1.01 0.334 7401 34460 all phecode
352 Disorders of other cranial nerves Neurological 1.02 0.968 – 1.07 0.52 1714 17106 all phecode
352.1 Trigeminal nerve disorders [CN5] Neurological 1 0.92 – 1.1 0.936 535 5344 all phecode
352.2 Facial nerve disorders [CN7] Neurological 0.999 0.927 – 1.08 0.972 783 7826 all phecode
353 Nerve root and plexus disorders Neurological 0.98 0.949 – 1.01 0.207 4256 33369 all phecode
353.1 Nerve plexus lesions Neurological 0.958 0.862 – 1.07 0.429 390 3900 all phecode
353.2 Nerve root lesions Neurological 1.17 0.992 – 1.38 0.0626 130 1287 all phecode
355 Complex regional/central pain syndrome Neurological 0.953 0.87 – 1.04 0.308 531 5295 all phecode
355.1 Chronic pain syndrome Neurological 0.971 0.903 – 1.04 0.424 843 8386 all phecode
356 Hereditary and idiopathic peripheral neuropathy Neurological 1.01 0.968 – 1.05 0.653 2335 20731 all phecode
357 Inflammatory and toxic neuropathy Neurological 0.99 0.956 – 1.03 0.595 3472 29956 all phecode
358 Myoneural disorders Neurological 1.05 0.991 – 1.11 0.0992 1147 11391 all phecode
358.1 Myasthenia gravis Neurological 1.08 0.899 – 1.3 0.406 109 1082 all phecode
359 Muscular dystrophies and other myopathies Neurological 0.97 0.913 – 1.03 0.333 1134 11274 all phecode
359.1 Muscular dystrophies Neurological 0.786 0.587 – 1.05 0.104 64 632 all phecode
359.2 Myopathy Neurological 0.979 0.92 – 1.04 0.492 1092 10843 all phecode
360 Disorders of the globe Sense Organs 1.09 0.91 – 1.3 0.356 131 1276 all phecode
360.2 Progressive myopia Sense Organs 1.18 0.913 – 1.53 0.206 65 640 all phecode
361 Retinal detachments and defects Sense Organs 1.01 0.933 – 1.08 0.876 733 7131 all phecode
361.1 Retinal detachment with retinal defect Sense Organs 0.946 0.838 – 1.07 0.371 302 2962 all phecode
362 Other retinal disorders Sense Organs 0.997 0.962 – 1.03 0.873 3569 22997 all phecode
362.2
Degeneration of macula and posterior pole of
Degeneration of macula and posterior pole of retina
 Sense Organs 0.994 0.95 – 1.04 0.782 2172 15483 all phecode
362.21 Macular degeneration, dry Sense Organs 1.01 0.917 – 1.12 0.799 419 3438 all phecode
362.22 Macular degeneration, wet Sense Organs 1.03 0.863 – 1.22 0.765 148 1184 all phecode
362.23 Cystoid macular degeneration of retina Sense Organs 1.1 1.01 – 1.21 0.0362 408 3839 all phecode
362.26 Macular puckering of retina Sense Organs 1 0.939 – 1.07 0.948 976 8610 all phecode
362.27 Drusen (degenerative) of retina Sense Organs 1.02 0.927 – 1.11 0.742 488 4558 all phecode
362.29 Macular degeneration (senile) of retina NOS Sense Organs 0.984 0.938 – 1.03 0.52 1883 13955 all phecode
362.3 Other nondiabetic retinopathy Sense Organs 1.03 0.965 – 1.1 0.382 976 8527 all phecode
362.31 Separation of retinal layers Sense Organs 1.04 0.941 – 1.15 0.445 413 4056 all phecode
362.4 Retinal vascular changes and abnomalities Sense Organs 1.03 0.947 – 1.11 0.527 662 5933 all phecode
362.6 Peripheral retinal degenerations Sense Organs 0.952 0.858 – 1.06 0.358 392 3787 all phecode
362.7 Hereditary retinal dystrophies Sense Organs 1.07 0.932 – 1.22 0.347 215 2103 all phecode
362.8 Retinal hemorrhage/ischemia Sense Organs 0.897 0.782 – 1.03 0.12 241 2368 all phecode
362.9 Retinal edema Sense Organs 1.14 1.03 – 1.27 0.0144 324 2936 all phecode
363
Chorioretinal inflammations, scars, and other
Chorioretinal inflammations, scars, and other disorders of choroid
 Sense Organs 1.04 0.947 – 1.14 0.434 492 4746 all phecode
363.3 Chorioretinal scars Sense Organs 0.97 0.864 – 1.09 0.61 332 3184 all phecode
364 Corneal opacity and other disorders of cornea Sense Organs 1 0.946 – 1.07 0.881 1132 10772 all phecode
364.1 Corneal opacity Sense Organs 0.959 0.861 – 1.07 0.441 394 3846 all phecode
364.2 Corneal edema Sense Organs 1.1 0.922 – 1.31 0.298 123 1208 all phecode
364.4 Corneal degenerations Sense Organs 0.952 0.857 – 1.06 0.361 402 3962 all phecode
364.41 Keratoconus Sense Organs 0.772 0.593 – 1.01 0.0553 75 739 all phecode
364.5 Corneal dystrophy Sense Organs 1.01 0.928 – 1.11 0.778 502 4682 all phecode
364.51 Fuchs' dystrophy Sense Organs 1.05 0.937 – 1.18 0.39 266 2521 all phecode
364.9 Cornea replaced by transplant Sense Organs 1.12 0.916 – 1.37 0.267 91 885 all phecode
365 Glaucoma Sense Organs 0.997 0.957 – 1.04 0.885 2672 21326 all phecode
365.1 Open-angle glaucoma Sense Organs 1.02 0.946 – 1.1 0.593 705 6491 all phecode
365.11 Primary open angle glaucoma Sense Organs 1.01 0.912 – 1.12 0.853 403 3681 all phecode
365.2 Primary angle-closure glaucoma Sense Organs 0.971 0.854 – 1.1 0.652 251 2370 all phecode
366 Cataract Sense Organs 0.994 0.969 – 1.02 0.642 8611 28043 all phecode
366.1 Nonsenile Cataract Sense Organs 1.03 0.9 – 1.18 0.67 207 1979 all phecode
366.2 Senile cataract Sense Organs 0.994 0.964 – 1.02 0.678 5480 24980 all phecode
367
Disorders of refraction and accommodation
Disorders of refraction and accommodation; blindness and low vision
 Sense Organs 0.998 0.975 – 1.02 0.865 8967 37779 all phecode
367.1 Myopia Sense Organs 1.01 0.977 – 1.04 0.646 5014 34677 all phecode
367.2 Astigmatism Sense Organs 1 0.969 – 1.03 0.944 4161 32463 all phecode
367.8 Hypermetropia Sense Organs 1.02 0.973 – 1.07 0.428 2039 18599 all phecode
367.9 Blindness and low vision Sense Organs 1 0.945 – 1.06 0.995 1277 12356 all phecode
368 Visual disturbances Sense Organs 0.996 0.969 – 1.02 0.788 5715 39599 all phecode
368.1 Amblyopia Sense Organs 0.961 0.886 – 1.04 0.344 651 6479 all phecode
368.2 Diplopia and disorders of binocular vision Sense Organs 0.993 0.932 – 1.06 0.82 1087 10786 all phecode
368.3 Anisometropia Sense Organs 1.12 0.978 – 1.28 0.1 219 2168 all phecode
368.4 Visual field defects Sense Organs 0.985 0.927 – 1.05 0.633 1132 11173 all phecode
368.9 Subjective visual disturbances Sense Organs 1.01 0.949 – 1.07 0.776 1070 10620 all phecode
368.91 Psychophysical visual disturbances Sense Organs 1.06 0.877 – 1.28 0.552 120 1171 all phecode
369 Infection of the eye Sense Organs 1.01 0.971 – 1.04 0.701 3185 28240 all phecode
369.2 Eye infection, viral Sense Organs 0.944 0.858 – 1.04 0.239 502 4954 all phecode
369.5 Conjunctivitis, infectious Sense Organs 1.02 0.981 – 1.06 0.321 2716 24970 all phecode
370 Keratitis Sense Organs 1 0.947 – 1.06 0.979 1365 13169 all phecode
370.1 Corneal ulcer Sense Organs 0.998 0.869 – 1.15 0.975 223 2194 all phecode
370.2 Superficial keratitis Sense Organs 1.01 0.924 – 1.1 0.838 546 5393 all phecode
370.3 Keratoconjunctivitis Sense Organs 1.01 0.936 – 1.1 0.742 649 6263 all phecode
370.31 Keratoconjunctivitis sicca Sense Organs 0.842 0.715 – 0.991 0.0387 179 1677 all phecode
371 Inflammation of the eye Sense Organs 1 0.97 – 1.03 0.963 4414 32310 all phecode
371.1 Uveitis, noninfectious or NOS Sense Organs 1 0.914 – 1.09 0.999 541 5278 all phecode
371.2 Conjunctivitis, noninfectious Sense Organs 1.04 0.972 – 1.11 0.256 906 8939 all phecode
371.21 Allergic conjunctivitis Sense Organs 1.04 0.965 – 1.12 0.318 756 7515 all phecode
371.3 Inflammation of eyelids Sense Organs 1.01 0.973 – 1.05 0.642 3398 26983 all phecode
371.33 Noninfectious dermatoses of eyelid Sense Organs 1.06 0.891 – 1.25 0.528 133 1291 all phecode
372 Disorders of conjunctiva Sense Organs 1.01 0.954 – 1.08 0.663 1118 10728 all phecode
374 Other disorders of eyelids Sense Organs 0.988 0.951 – 1.03 0.547 2940 24188 all phecode
374.1 Ectropion or entropion Sense Organs 0.975 0.882 – 1.08 0.618 431 4084 all phecode
374.2 Lagophthalmos Sense Organs 1.04 0.909 – 1.19 0.575 235 2335 all phecode
374.3 Ptosis of eyelid Sense Organs 0.99 0.93 – 1.05 0.743 1102 10734 all phecode
374.6 Dermatochalasis Sense Organs 0.981 0.92 – 1.05 0.568 1040 9720 all phecode
375 Disorders of lacrimal system Sense Organs 0.993 0.959 – 1.03 0.677 3694 26045 all phecode
375.1 Dry eyes Sense Organs 0.994 0.961 – 1.03 0.722 4040 26751 all phecode
375.2 Epiphora Sense Organs 0.994 0.902 – 1.1 0.902 442 4354 all phecode
376 Disorders of the orbit Sense Organs 1.1 0.993 – 1.23 0.0661 352 3508 all phecode
377 Disorders of optic nerve and visual pathways Sense Organs 1 0.939 – 1.07 0.9 913 9021 all phecode
377.1 Optic atrophy Sense Organs 1.04 0.924 – 1.18 0.493 283 2793 all phecode
377.3 Optic neuritis/neuropathy Sense Organs 1.04 0.959 – 1.13 0.338 585 5775 all phecode
378
Strabismus and other disorders of binocular eye
Strabismus and other disorders of binocular eye movements
 Sense Organs 0.966 0.911 – 1.02 0.237 1275 12460 all phecode
378.1 Strabismus (not specified as paralytic) Sense Organs 0.946 0.879 – 1.02 0.139 828 8130 all phecode
378.2 Nystagmus and other irregular eye movements Sense Organs 0.956 0.819 – 1.12 0.569 170 1686 all phecode
378.5 Paralytic strabismus Sense Organs 0.916 0.817 – 1.03 0.131 349 3437 all phecode
379 Other disorders of eye Sense Organs 1.01 0.976 – 1.04 0.683 5046 29999 all phecode
379.1 Scleritis and episcleritis Sense Organs 0.983 0.844 – 1.15 0.83 176 1743 all phecode
379.2 Disorders of vitreous body Sense Organs 1 0.967 – 1.04 0.926 3634 23186 all phecode
379.3 Aphakia and other disorders of lens Sense Organs 0.824 0.676 – 1 0.0549 135 1258 all phecode
379.4 Anomalies of pupillary function Sense Organs 0.961 0.852 – 1.08 0.521 287 2833 all phecode
379.5 Disorders of iris and ciliary body Sense Organs 1 0.889 – 1.13 0.987 304 2948 all phecode
379.51 Pigmentary iris degeneration Sense Organs 1.05 0.843 – 1.31 0.656 77 731 all phecode
379.9 Pain, swelling or discharge of eye Sense Organs 0.96 0.903 – 1.02 0.198 1129 11130 all phecode
380 Disorders of external ear Sense Organs 1.04 1 – 1.09 0.0506 2242 20393 all phecode
380.1 Otitis externa Sense Organs 1.03 0.979 – 1.09 0.239 1469 14580 all phecode
380.4 Impacted cerumen Sense Organs 1.03 0.991 – 1.07 0.128 2648 23557 all phecode
381 Otitis media and Eustachian tube disorders Sense Organs 0.995 0.963 – 1.03 0.74 4255 36417 all phecode
381.1 Otitis media Sense Organs 1 0.966 – 1.04 0.906 3079 29813 all phecode
381.11 Suppurative and unspecified otitis media Sense Organs 1.02 0.976 – 1.06 0.453 2610 25602 all phecode
381.2 Eustachian tube disorders Sense Organs 0.994 0.947 – 1.04 0.8 1816 17827 all phecode
381.3 Mastoiditis & related conditions Sense Organs 1.06 0.902 – 1.25 0.466 153 1530 all phecode
381.9 Otorrhea Sense Organs 1.03 0.921 – 1.14 0.643 372 3713 all phecode
382 Otalgia Sense Organs 0.995 0.949 – 1.04 0.84 1884 18673 all phecode
383 Otosclerosis Sense Organs 0.903 0.744 – 1.1 0.303 124 1240 all phecode
384 Other disorders of tympanic membrane Sense Organs 1.04 0.95 – 1.14 0.404 516 5156 all phecode
384.1 Myringitis Sense Organs 1.02 0.796 – 1.32 0.849 51 502 all phecode
384.4 Perforation of tympanic membrane Sense Organs 1.03 0.931 – 1.14 0.57 403 4029 all phecode
385 Other disorders of middle ear and mastoid Sense Organs 0.956 0.863 – 1.06 0.388 432 4320 all phecode
385.3 Cholesteatoma Sense Organs 0.922 0.808 – 1.05 0.228 277 2770 all phecode
385.5
Tympanosclerosis and middle ear disease related
Tympanosclerosis and middle ear disease related to otitis media
 Sense Organs 0.941 0.776 – 1.14 0.536 118 1180 all phecode
386
Vertiginous syndromes and other disorders of
Vertiginous syndromes and other disorders of vestibular system
 Sense Organs 1.03 0.98 – 1.08 0.265 1882 18186 all phecode
386.1 Meniere's disease Sense Organs 1.01 0.904 – 1.13 0.822 319 3156 all phecode
386.2 Peripheral or central vertigo Sense Organs 1.02 0.974 – 1.08 0.351 1586 15423 all phecode
386.21 Central origin vertigo Sense Organs 1.01 0.955 – 1.07 0.672 1208 11844 all phecode
386.3 Labyrinthitis Sense Organs 1.02 0.964 – 1.07 0.534 1482 14530 all phecode
386.9
Dizziness and giddiness (Light-headedness and
Dizziness and giddiness (Light-headedness and vertigo)
 Sense Organs 0.986 0.961 – 1.01 0.298 6933 38286 all phecode
388 Other disorders of ear Sense Organs 1.04 0.974 – 1.11 0.253 960 9501 all phecode
389 Hearing loss Sense Organs 0.997 0.973 – 1.02 0.784 8182 38069 all phecode
389.1 Sensorineural hearing loss Sense Organs 0.98 0.948 – 1.01 0.233 4107 29258 all phecode
389.2 Conductive hearing loss Sense Organs 0.977 0.911 – 1.05 0.514 905 9042 all phecode
389.3 Degenerative and vascular disorders of ear Sense Organs 1.03 0.893 – 1.19 0.666 192 1808 all phecode
389.4 Tinnitus Sense Organs 1.01 0.971 – 1.06 0.547 2291 22130 all phecode
389.5 Disorders of acoustic nerve Sense Organs 1.17 0.992 – 1.38 0.0619 124 1229 all phecode
394 Rheumatic disease of the heart valves Circulatory System 1.02 0.963 – 1.07 0.566 1458 13732 all phecode
394.1 Mitral valve stenosis and aortic valve stenosis Circulatory System 1 0.899 – 1.12 0.983 350 3415 all phecode
394.2 Mitral valve disease Circulatory System 0.98 0.89 – 1.08 0.68 462 4560 all phecode
394.3 Aortic valve disease Circulatory System 1.02 0.877 – 1.19 0.773 176 1691 all phecode
394.4 Acute rheumatic heart disease Circulatory System 1 0.755 – 1.32 0.999 55 546 all phecode
394.7 Disease of tricuspid valve Circulatory System 1.09 1.01 – 1.18 0.0337 587 5739 all phecode
395 Heart valve disorders Circulatory System 1 0.969 – 1.04 0.919 3976 28748 all phecode
395.1 Nonrheumatic mitral valve disorders Circulatory System 1.01 0.965 – 1.05 0.723 2175 20441 all phecode
395.2 Nonrheumatic aortic valve disorders Circulatory System 1.02 0.975 – 1.07 0.382 2060 17194 all phecode
395.3 Nonrheumatic tricuspid valve disorders Circulatory System 1 0.912 – 1.1 0.986 493 4864 all phecode
395.4 Nonrheumatic pulmonary valve disorders Circulatory System 0.969 0.79 – 1.19 0.76 108 1080 all phecode
395.6 Heart valve replaced Circulatory System 1.01 0.956 – 1.08 0.626 1177 10833 all phecode
396 Abnormal heart sounds Circulatory System 1 0.972 – 1.03 0.887 4718 34395 all phecode
401 Hypertension Circulatory System 1.01 0.985 – 1.03 0.608 23317 23367 all phecode
401.1 Essential hypertension Circulatory System 1 0.984 – 1.03 0.659 23158 23364 all phecode
401.2 Hypertensive heart and/or renal disease Circulatory System 0.99 0.951 – 1.03 0.611 3503 14616 all phecode
401.21 Hypertensive heart disease Circulatory System 0.992 0.924 – 1.06 0.815 893 6607 all phecode
401.22 Hypertensive chronic kidney disease Circulatory System 0.985 0.942 – 1.03 0.518 2584 13072 all phecode
401.3 Other hypertensive complications Circulatory System 0.992 0.951 – 1.04 0.715 2679 15833 all phecode
411 Ischemic Heart Disease Circulatory System 1.01 0.985 – 1.04 0.427 8807 30299 all phecode
411.1 Unstable angina (intermediate coronary syndrome) Circulatory System 1.01 0.945 – 1.08 0.769 937 8574 all phecode
411.2 Myocardial infarction Circulatory System 1.01 0.973 – 1.05 0.63 3594 21716 all phecode
411.3 Angina pectoris Circulatory System 1.01 0.968 – 1.05 0.671 2485 18304 all phecode
411.4 Coronary atherosclerosis Circulatory System 1.02 0.989 – 1.04 0.242 7555 27492 all phecode
411.41 Aneurysm and dissection of heart Circulatory System 0.968 0.817 – 1.15 0.705 156 1529 all phecode
411.8
Other chronic ischemic heart disease
Other chronic ischemic heart disease, unspecified
 Circulatory System 1.01 0.979 – 1.04 0.612 6331 25741 all phecode
411.9
Other acute and subacute forms of ischemic
Other acute and subacute forms of ischemic heart disease
 Circulatory System 0.976 0.886 – 1.07 0.617 442 4211 all phecode
414 Other forms of chronic heart disease Circulatory System 1.03 0.991 – 1.07 0.137 3101 22616 all phecode
414.2 ASCVD Circulatory System 1.06 0.983 – 1.14 0.133 718 6816 all phecode
415 Pulmonary heart disease Circulatory System 0.994 0.959 – 1.03 0.738 3366 30208 all phecode
415.1 Acute pulmonary heart disease Circulatory System 0.968 0.923 – 1.02 0.187 1912 19014 all phecode
415.11 Pulmonary embolism and infarction, acute Circulatory System 0.969 0.924 – 1.02 0.199 1906 18953 all phecode
415.2 Chronic pulmonary heart disease Circulatory System 1.02 0.974 – 1.07 0.394 1808 17605 all phecode
415.21 Primary pulmonary hypertension Circulatory System 0.99 0.917 – 1.07 0.797 706 7032 all phecode
416 Cardiomegaly Circulatory System 1.01 0.951 – 1.07 0.804 1254 12372 all phecode
418 Nonspecific chest pain Circulatory System 1.01 0.986 – 1.03 0.551 12650 33952 all phecode
418.1 Precordial pain Circulatory System 1.01 0.96 – 1.07 0.642 1471 13782 all phecode
420 Carditis Circulatory System 0.993 0.943 – 1.05 0.791 1588 15680 all phecode
420.1 Myocarditis Circulatory System 1.04 0.848 – 1.27 0.716 97 958 all phecode
420.2 Pericarditis Circulatory System 1.01 0.944 – 1.09 0.73 842 8402 all phecode
420.21 Acute pericarditis Circulatory System 0.968 0.83 – 1.13 0.675 177 1764 all phecode
420.22 Chronic pericarditis Circulatory System 1.14 0.952 – 1.37 0.154 117 1153 all phecode
420.3 Endocarditis Circulatory System 0.988 0.916 – 1.07 0.761 764 7535 all phecode
425 Cardiomyopathy Circulatory System 1.03 0.989 – 1.08 0.137 2078 19881 all phecode
425.1 Primary/intrinsic cardiomyopathies Circulatory System 1.04 0.995 – 1.09 0.0834 1989 19025 all phecode
425.11 Hypertrophic obstructive cardiomyopathy Circulatory System 1.04 0.9 – 1.19 0.624 208 2050 all phecode
425.12 Other hypertrophic cardiomyopathy Circulatory System 1.06 0.923 – 1.22 0.403 201 1992 all phecode
425.2 Secondary/extrinsic cardiomyopathies Circulatory System 1.01 0.897 – 1.13 0.912 317 3170 all phecode
425.8 Other cardiomyopathy Circulatory System 0.903 0.727 – 1.12 0.352 95 931 all phecode
426 Cardiac conduction disorders Circulatory System 0.995 0.972 – 1.02 0.672 12327 25440 all phecode
426.2 Atrioventricular [AV] block Circulatory System 0.984 0.936 – 1.04 0.538 1903 11501 all phecode
426.21 First degree AV block Circulatory System 0.974 0.917 – 1.03 0.381 1313 8899 all phecode
426.22 Mobitz II AV block Circulatory System 0.982 0.768 – 1.26 0.887 64 553 all phecode
426.23 Second degree AV block Circulatory System 1.07 0.94 – 1.23 0.291 216 1925 all phecode
426.24 Atrioventricular block, complete Circulatory System 1.03 0.941 – 1.14 0.483 461 3823 all phecode
426.25 Other heart block Circulatory System 1.01 0.869 – 1.16 0.944 203 1803 all phecode
426.3 Bundle branch block Circulatory System 1.02 0.981 – 1.07 0.276 2306 13999 all phecode
426.31 Right bundle branch block Circulatory System 1.03 0.974 – 1.09 0.31 1423 10758 all phecode
426.32 Left bundle branch block Circulatory System 1.01 0.944 – 1.08 0.805 969 8110 all phecode
426.4 Anomalous atrioventricular excitation Circulatory System 1.15 0.929 – 1.43 0.195 82 820 all phecode
426.7 Abnormal electrocardiogram [ECG] [EKG] Circulatory System 0.991 0.967 – 1.02 0.462 10577 25186 all phecode
426.8 Other cardiac conduction disorders Circulatory System 1.04 0.959 – 1.12 0.377 679 6650 all phecode
426.9 Cardiac pacemaker/device in situ Circulatory System 1 0.954 – 1.06 0.866 1754 11536 all phecode
426.91 Cardiac pacemaker in situ Circulatory System 1.02 0.955 – 1.08 0.61 1171 8184 all phecode
426.92 Cardiac defibrillator in situ Circulatory System 0.998 0.929 – 1.07 0.955 846 7320 all phecode
427 Cardiac dysrhythmias Circulatory System 1 0.985 – 1.02 0.652 17397 25735 all phecode
427.1 Paroxysmal tachycardia, unspecified Circulatory System 1.03 0.989 – 1.07 0.155 2474 18178 all phecode
427.11 Paroxysmal supraventricular tachycardia Circulatory System 1.03 0.982 – 1.09 0.208 1595 14293 all phecode
427.12 Paroxysmal ventricular tachycardia Circulatory System 1.01 0.949 – 1.07 0.798 1181 9915 all phecode
427.2 Atrial fibrillation and flutter Circulatory System 1 0.969 – 1.03 0.962 5313 18688 all phecode
427.21 Atrial fibrillation Circulatory System 1 0.969 – 1.03 0.942 5188 18409 all phecode
427.22 Atrial flutter Circulatory System 0.998 0.947 – 1.05 0.932 1693 11042 all phecode
427.3 Other specified cardiac dysrhythmias Circulatory System 0.998 0.973 – 1.02 0.89 8688 25552 all phecode
427.4 Cardiac arrest and ventricular fibrillation Circulatory System 1.05 0.966 – 1.15 0.241 536 5233 all phecode
427.41 Ventricular fibrillation and flutter Circulatory System 1.02 0.894 – 1.17 0.74 216 2118 all phecode
427.42 Cardiac arrest Circulatory System 1.04 0.938 – 1.15 0.469 410 4034 all phecode
427.5 Arrhythmia (cardiac) NOS Circulatory System 1 0.975 – 1.03 0.886 6905 25457 all phecode
427.6 Premature beats Circulatory System 1.03 0.991 – 1.08 0.119 2359 16248 all phecode
427.61 Supraventricular premature beats Circulatory System 0.999 0.924 – 1.08 0.977 670 6287 all phecode
427.7 Tachycardia NOS Circulatory System 1.01 0.981 – 1.04 0.471 5124 25531 all phecode
427.8 Sinoatrial node dysfunction (Bradycardia) Circulatory System 1.04 0.976 – 1.12 0.217 912 7501 all phecode
427.9 Palpitations Circulatory System 1 0.972 – 1.04 0.811 4430 24505 all phecode
428 Congestive heart failure; nonhypertensive Circulatory System 0.993 0.96 – 1.03 0.677 4300 23663 all phecode
428.1 Congestive heart failure (CHF) NOS Circulatory System 0.991 0.957 – 1.03 0.631 3756 22446 all phecode
428.2 Heart failure NOS Circulatory System 1 0.968 – 1.04 0.864 3701 21722 all phecode
428.3
Heart failure with reduced EF [Systolic or
Heart failure with reduced EF [Systolic or combined heart failure]
 Circulatory System 1.02 0.974 – 1.07 0.368 1765 14476 all phecode
428.4
Heart failure with preserved EF [Diastolic
Heart failure with preserved EF [Diastolic heart failure]
 Circulatory System 1 0.955 – 1.06 0.848 1648 13395 all phecode
429
Ill-defined descriptions and complications of
Ill-defined descriptions and complications of heart disease
 Circulatory System 0.988 0.968 – 1.01 0.283 12635 32504 all phecode
429.1 Heart transplant/surgery Circulatory System 0.99 0.934 – 1.05 0.742 1219 11696 all phecode
429.2 Abnormal function study of cardiovascular system Circulatory System 0.985 0.958 – 1.01 0.292 6322 29232 all phecode
429.3 Symptoms involving cardiovascular system Circulatory System 0.996 0.973 – 1.02 0.747 9650 32421 all phecode
429.9 Cardiac complications, not elsewhere classified Circulatory System 1.02 0.943 – 1.1 0.64 723 7072 all phecode
430 Intracranial hemorrhage Circulatory System 1.05 0.981 – 1.13 0.15 789 7842 all phecode
430.1 Subarachnoid hemorrhage Circulatory System 1.09 0.968 – 1.23 0.149 261 2610 all phecode
430.2 Intracerebral hemorrhage Circulatory System 1.06 0.958 – 1.17 0.258 368 3671 all phecode
430.3 Subdural hemorrhage Circulatory System 1.08 0.96 – 1.21 0.205 272 2680 all phecode
433 Cerebrovascular disease Circulatory System 0.999 0.97 – 1.03 0.959 5463 32242 all phecode
433.1 Occlusion and stenosis of precerebral arteries Circulatory System 0.958 0.913 – 1.01 0.082 1978 16212 all phecode
433.11
Occlusion of cerebral arteries, with cerebral
Occlusion of cerebral arteries, with cerebral infarction
 Circulatory System 1.02 0.898 – 1.15 0.782 260 2517 all phecode
433.12 Cerebral atherosclerosis Circulatory System 0.85 0.661 – 1.09 0.205 80 789 all phecode
433.2 Occlusion of cerebral arteries Circulatory System 0.992 0.951 – 1.03 0.704 2437 21732 all phecode
433.21
Cerebral artery occlusion, with cerebral
Cerebral artery occlusion, with cerebral infarction
 Circulatory System 0.991 0.949 – 1.03 0.681 2357 21103 all phecode
433.3 Cerebral ischemia Circulatory System 1.01 0.968 – 1.05 0.726 2780 22868 all phecode
433.31 Transient cerebral ischemia Circulatory System 1 0.961 – 1.05 0.909 2409 20762 all phecode
433.5 Cerebral aneurysm Circulatory System 1.03 0.937 – 1.13 0.562 474 4724 all phecode
433.6 Acute, but ill-defined cerebrovascular disease Circulatory System 1.05 0.958 – 1.15 0.3 464 4518 all phecode
433.8 Late effects of cerebrovascular disease Circulatory System 0.955 0.881 – 1.03 0.26 695 6822 all phecode
440 Atherosclerosis Circulatory System 0.996 0.955 – 1.04 0.839 2477 19724 all phecode
440.1 Atherosclerosis of renal artery Circulatory System 0.942 0.818 – 1.08 0.405 231 2291 all phecode
440.2 Atherosclerosis of the extremities Circulatory System 0.973 0.922 – 1.03 0.311 1516 13532 all phecode
440.21
Atherosclerosis of native arteries of the
Atherosclerosis of native arteries of the extremities with ulceration or gangrene
 Circulatory System 1.05 0.931 – 1.18 0.429 274 2669 all phecode
440.22
Atherosclerosis of native arteries of the
Atherosclerosis of native arteries of the extremities with intermittent claudication
 Circulatory System 0.975 0.914 – 1.04 0.433 1040 9647 all phecode
440.9 Atherosclerosis of aorta Circulatory System 1.03 0.962 – 1.1 0.391 846 8124 all phecode
441 Vascular insufficiency of intestine Circulatory System 1.03 0.94 – 1.12 0.554 515 5115 all phecode
441.1 Acute vascular insufficiency of intestine Circulatory System 1.07 0.942 – 1.21 0.303 240 2387 all phecode
441.2 Chronic vascular insufficiency of intestine Circulatory System 0.982 0.837 – 1.15 0.821 154 1536 all phecode
442 Other aneurysm Circulatory System 1.01 0.967 – 1.05 0.75 2779 21466 all phecode
442.1 Aortic aneurysm Circulatory System 1 0.957 – 1.05 0.918 2054 16492 all phecode
442.11 Abdominal aortic aneurysm Circulatory System 0.938 0.882 – 0.998 0.043 1189 10558 all phecode
442.2 Aneurysm of iliac artery Circulatory System 0.961 0.833 – 1.11 0.589 202 2002 all phecode
442.3 Aneurysm of artery of lower extremity Circulatory System 0.904 0.767 – 1.07 0.231 179 1765 all phecode
442.4 Arterial dissection Circulatory System 1.07 0.933 – 1.24 0.319 184 1840 all phecode
442.8 Aneurysm of other specified artery Circulatory System 1.04 0.944 – 1.15 0.402 399 3978 all phecode
443 Peripheral vascular disease Circulatory System 0.981 0.944 – 1.02 0.311 3086 24814 all phecode
443.1 Raynaud's syndrome Circulatory System 0.967 0.896 – 1.04 0.383 742 7390 all phecode
443.7
Peripheral angiopathy in diseases classified
Peripheral angiopathy in diseases classified elsewhere
 Circulatory System 0.978 0.852 – 1.12 0.754 220 2087 all phecode
443.8 Other specified peripheral vascular diseases Circulatory System 0.979 0.94 – 1.02 0.327 2557 21985 all phecode
443.9 Peripheral vascular disease, unspecified Circulatory System 0.986 0.944 – 1.03 0.524 2341 18862 all phecode
444 Arterial embolism and thrombosis Circulatory System 0.965 0.898 – 1.04 0.331 848 8423 all phecode
444.1
Arterial embolism and thrombosis of lower
Arterial embolism and thrombosis of lower extremity artery
 Circulatory System 0.975 0.868 – 1.1 0.677 313 3099 all phecode
444.2 Embolism and thrombosis of abdominal aorta Circulatory System 0.867 0.728 – 1.03 0.112 155 1548 all phecode
446 Polyarteritis nodosa and allied conditions Circulatory System 1.06 0.968 – 1.17 0.198 460 4559 all phecode
446.4 Wegener's granulomatosis Circulatory System 1.08 0.903 – 1.29 0.4 109 1075 all phecode
446.5 Giant cell arteritis Circulatory System 1.02 0.81 – 1.28 0.877 79 749 all phecode
446.9 Arteritis NOS Circulatory System 1.02 0.904 – 1.15 0.745 289 2876 all phecode
447 Other disorders of arteries and arterioles Circulatory System 1.03 0.992 – 1.07 0.121 2647 22765 all phecode
447.1 Stricture of artery Circulatory System 1.01 0.922 – 1.1 0.883 523 5163 all phecode
447.7 Aortic ectasia Circulatory System 1.05 0.98 – 1.13 0.162 804 7938 all phecode
448 Disease of capillaries Circulatory System 0.943 0.889 – 1 0.0563 1237 12127 all phecode
450 Noninfectious disorders of lymphatic channels Circulatory System 1.01 0.971 – 1.06 0.508 2104 20985 all phecode
451 Phlebitis and thrombophlebitis Circulatory System 0.989 0.917 – 1.07 0.768 738 7355 all phecode
451.2
Phlebitis and thrombophlebitis of lower
Phlebitis and thrombophlebitis of lower extremities
 Circulatory System 0.949 0.83 – 1.08 0.439 244 2437 all phecode
452 Other venous embolism and thrombosis Circulatory System 0.974 0.945 – 1 0.0972 4957 29867 all phecode
452.1 Iatrogenic pulmonary embolism and infarction Circulatory System 0.879 0.772 – 1 0.0515 276 2747 all phecode
452.2 Deep vein thrombosis [DVT] Circulatory System 0.956 0.921 – 0.993 0.0188 3260 26940 all phecode
452.8 Postphlebitic syndrome Circulatory System 1.07 0.917 – 1.26 0.38 154 1529 all phecode
453 Chronic venous hypertension Circulatory System 0.917 0.788 – 1.07 0.265 220 2168 all phecode
454 Varicose veins Circulatory System 0.994 0.956 – 1.03 0.767 2827 24555 all phecode
454.1 Varicose veins of lower extremity Circulatory System 0.985 0.944 – 1.03 0.482 2469 21426 all phecode
454.11 Varicose veins of lower extremity, symptomtic Circulatory System 0.985 0.935 – 1.04 0.579 1565 15056 all phecode
455 Hemorrhoids Circulatory System 0.999 0.97 – 1.03 0.921 5799 29818 all phecode
456 Chronic venous insufficiency [CVI] Circulatory System 0.982 0.946 – 1.02 0.36 3097 24898 all phecode
457
Encounter for long-term (current) use of
Encounter for long-term (current) use of anticoagulants, antithrombotics, aspirin
 Circulatory System 1.02 0.974 – 1.07 0.41 2095 15309 all phecode
457.2
Encounter for long-term (current) use of
Encounter for long-term (current) use of antiplatelets/antithrombotics
 Circulatory System 1.04 0.926 – 1.16 0.54 324 3221 all phecode
457.3 Encounter for long-term (current) use of aspirin Circulatory System 1.02 0.973 – 1.07 0.426 1973 14689 all phecode
458 Hypotension Circulatory System 0.989 0.96 – 1.02 0.461 5091 32185 all phecode
458.1 Orthostatic hypotension Circulatory System 0.978 0.924 – 1.04 0.448 1344 12938 all phecode
458.2 Iatrogenic hypotension Circulatory System 0.952 0.893 – 1.01 0.126 1109 11012 all phecode
458.9 Hypotension NOS Circulatory System 0.985 0.955 – 1.02 0.358 4618 31186 all phecode
459 Other disorders of circulatory system Circulatory System 0.99 0.966 – 1.02 0.447 7825 34792 all phecode
459.1 Hemorrhage NOS Circulatory System 0.967 0.9 – 1.04 0.37 834 8215 all phecode
459.7 Blood vessel replaced Circulatory System 0.964 0.91 – 1.02 0.22 1305 13023 all phecode
459.9 Circulatory disease NEC Circulatory System 0.993 0.966 – 1.02 0.586 6706 33592 all phecode
464 Acute sinusitis Respiratory 1 0.973 – 1.03 0.832 4792 32137 all phecode
465
Acute upper respiratory infections of multiple
Acute upper respiratory infections of multiple or unspecified sites
 Respiratory 1 0.98 – 1.03 0.79 9601 35915 all phecode
465.2 Acute pharyngitis Respiratory 1 0.971 – 1.03 0.974 5310 32365 all phecode
465.4 Acute laryngitis and tracheitis Respiratory 1.11 1.01 – 1.21 0.034 443 4428 all phecode
470 Septal Deviations/Turbinate Hypertrophy Respiratory 0.982 0.935 – 1.03 0.473 1797 17640 all phecode
471 Nasal polyps Respiratory 0.967 0.888 – 1.05 0.448 592 5881 all phecode
472 Chronic pharyngitis and nasopharyngitis Respiratory 1.03 0.984 – 1.08 0.189 1797 16986 all phecode
473 Diseases of the larynx and vocal cords Respiratory 1.01 0.977 – 1.05 0.448 2983 25244 all phecode
473.1 Chronic laryngitis Respiratory 1.11 0.879 – 1.39 0.387 68 674 all phecode
473.3 Paralysis/spasm of vocal cords or larynx Respiratory 1.03 0.953 – 1.12 0.427 628 6254 all phecode
473.4 Voice disturbance Respiratory 1.02 0.979 – 1.07 0.317 2336 21975 all phecode
474 Acute and chronic tonsillitis Respiratory 0.974 0.907 – 1.05 0.477 880 7892 all phecode
474.1 Acute tonsillitis Respiratory 0.978 0.873 – 1.09 0.698 335 3181 all phecode
474.2 Chronic tonsillitis and adenoiditis Respiratory 1 0.926 – 1.09 0.953 700 6445 all phecode
475 Chronic sinusitis Respiratory 1 0.972 – 1.04 0.817 4378 27891 all phecode
475.9 Postnasal drip Respiratory 1.02 0.956 – 1.09 0.527 922 9017 all phecode
476 Allergic rhinitis Respiratory 1.01 0.987 – 1.03 0.438 12687 28117 all phecode
477 Epistaxis or throat hemorrhage Respiratory 1 0.945 – 1.07 0.886 1150 11318 all phecode
478 Throat pain Respiratory 0.978 0.884 – 1.08 0.66 426 4195 all phecode
479 Other upper respiratory disease Respiratory 0.999 0.971 – 1.03 0.94 5627 28048 all phecode
480 Pneumonia Respiratory 1.01 0.986 – 1.04 0.327 5947 37034 all phecode
480.1 Bacterial pneumonia Respiratory 1.02 0.96 – 1.08 0.523 1155 11495 all phecode
480.11 Pneumococcal pneumonia Respiratory 0.997 0.915 – 1.09 0.946 568 5644 all phecode
480.12 Pseudomonal pneumonia Respiratory 1.17 1.01 – 1.35 0.0353 153 1523 all phecode
480.13 MRSA pneumonia Respiratory 0.994 0.827 – 1.19 0.95 117 1165 all phecode
480.2 Viral pneumonia Respiratory 0.889 0.764 – 1.03 0.128 202 1992 all phecode
480.3 Pneumonia due to fungus (mycoses) Respiratory 1.11 0.949 – 1.3 0.191 159 1590 all phecode
480.5 Bronchopneumonia and lung abscess Respiratory 1.05 0.882 – 1.26 0.561 135 1312 all phecode
481 Influenza Respiratory 0.997 0.943 – 1.05 0.914 1355 13284 all phecode
483 Acute bronchitis and bronchiolitis Respiratory 0.99 0.955 – 1.03 0.567 3412 29871 all phecode
495 Asthma Respiratory 0.999 0.976 – 1.02 0.94 8671 33569 all phecode
495.1 Chronic obstructive asthma Respiratory 0.955 0.861 – 1.06 0.376 397 3925 all phecode
495.11 Chronic obstructive asthma with exacerbation Respiratory 0.888 0.701 – 1.12 0.322 81 802 all phecode
495.2 Asthma with exacerbation Respiratory 1.02 0.975 – 1.08 0.34 1629 16033 all phecode
496 Chronic airway obstruction Respiratory 1 0.971 – 1.03 0.995 5343 28343 all phecode
496.1 Emphysema Respiratory 0.979 0.936 – 1.02 0.353 2134 19414 all phecode
496.2 Chronic bronchitis Respiratory 1 0.969 – 1.04 0.923 4128 26624 all phecode
496.21 Obstructive chronic bronchitis Respiratory 1 0.97 – 1.04 0.803 3747 25467 all phecode
496.3 Bronchiectasis Respiratory 1.03 0.944 – 1.12 0.541 549 5453 all phecode
497 Bronchitis Respiratory 1.02 0.974 – 1.07 0.402 1946 18824 all phecode
498 Acute bronchospasm Respiratory 0.964 0.879 – 1.06 0.434 496 4943 all phecode
499 Cystic fibrosis Respiratory 0.898 0.756 – 1.07 0.219 151 1510 all phecode
500 Lung disease due to external agents Respiratory 1.01 0.922 – 1.1 0.889 557 5551 all phecode
500.1 Extrinsic allergic alveolitis Respiratory 1.1 0.912 – 1.33 0.312 92 920 all phecode
500.2 Pneumoconiosis Respiratory 0.995 0.788 – 1.26 0.967 78 764 all phecode
501 Pneumonitis due to inhalation of food or vomitus Respiratory 1.03 0.951 – 1.12 0.465 634 6225 all phecode
502 Postinflammatory pulmonary fibrosis Respiratory 1.07 1 – 1.15 0.048 815 8076 all phecode
503 Pulmonary congestion and hypostasis Respiratory 1.04 0.969 – 1.11 0.291 835 8243 all phecode
504 Other alveolar and parietoalveolar pneumonopathy Respiratory 1.01 0.928 – 1.1 0.827 595 5878 all phecode
504.1 Idiopathic fibrosing alveolitis Respiratory 0.976 0.871 – 1.09 0.677 311 3084 all phecode
505 Other pulmonary inflamation or edema Respiratory 0.987 0.939 – 1.04 0.624 1638 15749 all phecode
506 Empyema and pneumothorax Respiratory 0.975 0.938 – 1.01 0.198 2894 25235 all phecode
507 Pleurisy; pleural effusion Respiratory 1.01 0.975 – 1.05 0.514 2916 26208 all phecode
508
Pulmonary collapse; interstitial and
Pulmonary collapse; interstitial and compensatory emphysema
 Respiratory 1.01 0.971 – 1.05 0.582 2382 22588 all phecode
509 Respiratory failure, insufficiency, arrest Respiratory 1 0.967 – 1.03 0.985 4032 29477 all phecode
509.1 Respiratory failure Respiratory 0.968 0.923 – 1.01 0.173 1937 18949 all phecode
509.2 Respiratory insufficiency Respiratory 0.991 0.934 – 1.05 0.777 1174 11679 all phecode
509.3
Pulmonary insufficiency or respiratory failure
Pulmonary insufficiency or respiratory failure following trauma and surgery
 Respiratory 1.01 0.957 – 1.06 0.831 1689 16489 all phecode
509.8
Dependence on respirator [Ventilator] or
Dependence on respirator [Ventilator] or supplemental oxygen
 Respiratory 1.01 0.962 – 1.06 0.684 1741 17249 all phecode
510 Other diseases of lung Respiratory 1 0.973 – 1.03 0.923 5503 35907 all phecode
510.2 Lung transplant Respiratory 1.09 0.941 – 1.26 0.253 176 1757 all phecode
512 Other symptoms of respiratory system Respiratory 0.99 0.971 – 1.01 0.291 18621 28154 all phecode
512.1 Wheezing Respiratory 1 0.947 – 1.06 0.989 1409 13516 all phecode
512.2 Painful respiration Respiratory 1.02 0.975 – 1.06 0.43 2309 21263 all phecode
512.3 Abnormal chest sounds Respiratory 1.09 0.969 – 1.22 0.155 291 2845 all phecode
512.7 Shortness of breath Respiratory 1.01 0.983 – 1.03 0.624 10034 28081 all phecode
512.8 Cough Respiratory 0.988 0.965 – 1.01 0.318 9501 28148 all phecode
512.9 Other dyspnea Respiratory 0.996 0.974 – 1.02 0.75 10804 28104 all phecode
513 Respiratory abnormalities Respiratory 0.994 0.974 – 1.01 0.554 12932 33822 all phecode
513.3 Hypoventilation Respiratory 1 0.935 – 1.07 0.985 880 8646 all phecode
513.31 Apnea Respiratory 0.986 0.897 – 1.08 0.771 462 4607 all phecode
513.32 Orthopnea Respiratory 1.03 0.901 – 1.19 0.639 220 2160 all phecode
513.4 Hyperventilation Respiratory 0.999 0.913 – 1.09 0.99 515 5124 all phecode
513.8 Disorders of diaphragm Respiratory 0.939 0.823 – 1.07 0.348 258 2557 all phecode
514 Abnormal findings examination of lungs Respiratory 1 0.975 – 1.03 0.796 5365 34834 all phecode
514.1
Abnormal results of function study of pulmonary
Abnormal results of function study of pulmonary system
 Respiratory 1.05 0.927 – 1.19 0.445 258 2580 all phecode
514.2 Solitary pulmonary nodule Respiratory 1.02 0.979 – 1.05 0.408 3018 27338 all phecode
516 Abnormal sputum Respiratory 1.04 0.961 – 1.12 0.362 735 7332 all phecode
516.1 Hemoptysis Respiratory 1.03 0.954 – 1.12 0.413 611 6080 all phecode
519
Other diseases of respiratory system, not
Other diseases of respiratory system, not elsewhere classified
 Respiratory 0.992 0.965 – 1.02 0.533 6458 39057 all phecode
519.1 Tracheostomy complications Respiratory 1.11 0.973 – 1.27 0.119 214 2136 all phecode
519.2 Respiratory complications Respiratory 0.96 0.87 – 1.06 0.416 445 4430 all phecode
519.8 Other diseases of respiratory system, NEC Respiratory 0.967 0.917 – 1.02 0.207 1588 15787 all phecode
519.9
Symptoms involving respiratory system and other
Symptoms involving respiratory system and other chest symptoms
 Respiratory 1 0.975 – 1.04 0.757 4706 34489 all phecode
520 Disorders of tooth development Digestive 0.933 0.835 – 1.04 0.22 369 3690 all phecode
520.1 Hereditary disturbances in tooth structure Digestive 0.95 0.808 – 1.12 0.537 165 1642 all phecode
520.2 Disturbances in tooth eruption Digestive 0.88 0.757 – 1.02 0.0933 218 2172 all phecode
521 Diseases of hard tissues of teeth Digestive 0.963 0.898 – 1.03 0.286 898 8954 all phecode
521.1 Dental caries Digestive 0.967 0.9 – 1.04 0.36 837 8349 all phecode
521.2 Dental abrasion, erosion and attrition Digestive 1.09 0.834 – 1.43 0.523 52 510 all phecode
522 Diseases of pulp and periapical tissues Digestive 1.03 0.947 – 1.13 0.461 535 5340 all phecode
522.5 Periapical abscess Digestive 0.998 0.907 – 1.1 0.975 459 4583 all phecode
523 Gingival and periodontal diseases Digestive 1.04 0.964 – 1.12 0.311 718 7180 all phecode
523.1 Gingivitis Digestive 1.06 0.888 – 1.26 0.536 142 1418 all phecode
523.3 Periodontitis (acute or chronic) Digestive 1.01 0.911 – 1.13 0.789 364 3636 all phecode
523.31 Acute periodontitis Digestive 0.952 0.846 – 1.07 0.419 311 3109 all phecode
523.32 Chronic periodontitis Digestive 1.16 0.971 – 1.39 0.102 122 1204 all phecode
524 Dentofacial anomalies, including malocclusion Digestive 0.985 0.884 – 1.1 0.787 363 3630 all phecode
524.3 Anomalies of tooth position/malocclusion Digestive 1.06 0.928 – 1.21 0.39 220 2200 all phecode
525
Other diseases of the teeth and supporting
Other diseases of the teeth and supporting structures
 Digestive 0.959 0.899 – 1.02 0.207 1039 10382 all phecode
525.1 Loss of teeth or edentulism Digestive 1.01 0.909 – 1.13 0.838 374 3731 all phecode
526 Diseases of the jaws Digestive 1.03 0.988 – 1.07 0.17 2680 26455 all phecode
526.1 Cysts of the jaws Digestive 1.02 0.896 – 1.16 0.755 247 2470 all phecode
526.3 Anomalies of jaw size/symmetry Digestive 0.986 0.866 – 1.12 0.826 241 2383 all phecode
526.4 Temporomandibular joint disorders Digestive 1.04 0.984 – 1.09 0.184 1504 15025 all phecode
526.41 Temporomandibular joint disorder, unspecified Digestive 1.04 0.979 – 1.1 0.217 1187 11858 all phecode
526.42 Arthralgia/ankylosis of temporomandibular joint Digestive 1.04 0.967 – 1.12 0.295 741 7400 all phecode
526.5 Inflammatory conditions of jaw Digestive 1.09 0.966 – 1.23 0.165 287 2864 all phecode
526.8 Exostosis of jaw Digestive 0.85 0.635 – 1.14 0.275 53 521 all phecode
526.9 Jaw disease NOS Digestive 0.971 0.884 – 1.07 0.548 487 4867 all phecode
527 Diseases of the salivary glands Digestive 0.979 0.933 – 1.03 0.402 1781 17771 all phecode
527.1 Hypertrophy of salivary gland Digestive 0.794 0.594 – 1.06 0.119 58 579 all phecode
527.2 Sialoadenitis Digestive 1.05 0.947 – 1.16 0.374 394 3936 all phecode
527.7 Disturbance of salivary secretion Digestive 0.961 0.899 – 1.03 0.251 952 9481 all phecode
527.8 Other specified diseases of the salivary glands Digestive 0.953 0.836 – 1.09 0.471 254 2540 all phecode
528
Diseases of the oral soft tissues, excluding
Diseases of the oral soft tissues, excluding lesions specific for gingiva and tongue
 Digestive 0.982 0.943 – 1.02 0.382 2643 26197 all phecode
528.1 Stomatitis and mucositis Digestive 0.957 0.883 – 1.04 0.29 668 6657 all phecode
528.11 Stomatitis and mucositis (ulcerative) Digestive 0.954 0.826 – 1.1 0.525 211 2110 all phecode
528.12 Oral aphthae Digestive 1.05 0.918 – 1.2 0.467 215 2137 all phecode
528.3 Cellulitis and abscess of oral soft tissues Digestive 0.959 0.838 – 1.1 0.538 235 2338 all phecode
528.4 Cysts of oral soft tissues Digestive 0.93 0.765 – 1.13 0.466 124 1229 all phecode
528.41 Cyst of the salivary gland Digestive 1.04 0.824 – 1.32 0.727 77 760 all phecode
528.5 Diseases of lips Digestive 1.02 0.933 – 1.12 0.63 462 4602 all phecode
528.6 Leukoplakia of oral mucosa Digestive 1.01 0.845 – 1.2 0.929 137 1370 all phecode
528.7 Sialolithiasis Digestive 0.985 0.844 – 1.15 0.846 163 1623 all phecode
529 Diseases and other conditions of the tongue Digestive 0.98 0.906 – 1.06 0.618 690 6878 all phecode
529.1 Glossitis Digestive 0.92 0.766 – 1.11 0.377 129 1281 all phecode
529.6 Glossodynia Digestive 1.03 0.886 – 1.2 0.681 168 1652 all phecode
530 Diseases of esophagus Digestive 1 0.984 – 1.02 0.705 17081 27931 all phecode
530.1 Esophagitis, GERD and related diseases Digestive 1 0.983 – 1.02 0.823 16572 27931 all phecode
530.11 GERD Digestive 1 0.982 – 1.02 0.904 16143 27929 all phecode
530.12 Ulcer of esophagus Digestive 0.98 0.884 – 1.09 0.695 400 3983 all phecode
530.13 Barrett's esophagus Digestive 0.999 0.927 – 1.08 0.969 762 7584 all phecode
530.14 Reflux esophagitis Digestive 1.01 0.968 – 1.06 0.56 1900 17495 all phecode
530.15 Eosinophilic esophagitis Digestive 1.05 0.922 – 1.2 0.456 221 2210 all phecode
530.2 Esophageal bleeding (varices/hemorrhage) Digestive 1.04 0.962 – 1.12 0.321 651 6473 all phecode
530.3 Stricture and stenosis of esophagus Digestive 0.989 0.923 – 1.06 0.744 911 8971 all phecode
530.5 Disorders of esophageal motility Digestive 1.04 0.958 – 1.14 0.33 548 5432 all phecode
530.6 Diverticulum of esophagus, acquired Digestive 0.957 0.799 – 1.15 0.633 129 1265 all phecode
530.7 Gastroesophageal laceration-hemorrhage syndrome Digestive 0.904 0.71 – 1.15 0.413 82 812 all phecode
530.9 Heartburn Digestive 0.998 0.947 – 1.05 0.955 1519 14928 all phecode
531 Peptic ulcer (excl. esophageal) Digestive 1.01 0.964 – 1.05 0.706 2073 20617 all phecode
531.1 Hemorrhage from gastrointestinal ulcer Digestive 1 0.904 – 1.11 0.978 391 3883 all phecode
531.2 Gastric ulcer Digestive 0.986 0.929 – 1.05 0.648 1201 11970 all phecode
531.3 Duodenal ulcer Digestive 0.996 0.907 – 1.09 0.936 467 4640 all phecode
531.4 Peptic ulcer, site unspecified Digestive 1.06 0.993 – 1.14 0.08 804 8018 all phecode
531.5 Gastrojejunal ulcer Digestive 1.09 0.93 – 1.29 0.279 150 1500 all phecode
532 Dysphagia Digestive 0.998 0.969 – 1.03 0.902 5585 26852 all phecode
535 Gastritis and duodenitis Digestive 0.988 0.95 – 1.03 0.553 2799 27335 all phecode
535.1 Acute gastritis Digestive 0.96 0.903 – 1.02 0.196 1178 11750 all phecode
535.2 Atrophic gastritis Digestive 1.11 0.997 – 1.23 0.0566 344 3413 all phecode
535.6 Duodenitis Digestive 1.03 0.919 – 1.15 0.615 334 3337 all phecode
535.8 Other specified gastritis Digestive 1.01 0.936 – 1.1 0.742 638 6354 all phecode
535.9 Gastritis and duodenitis, NOS Digestive 1.02 0.962 – 1.08 0.513 1255 12511 all phecode
536 Disorders of function of stomach Digestive 1 0.962 – 1.04 0.986 2911 27685 all phecode
536.3 Gastroparesis Digestive 1.01 0.938 – 1.09 0.756 706 6901 all phecode
536.7
Complications of gastrostomy, colostomy and
Complications of gastrostomy, colostomy and enterostomy
 Digestive 1.05 0.951 – 1.16 0.324 407 4059 all phecode
536.8
Dyspepsia and other specified disorders of
Dyspepsia and other specified disorders of function of stomach
 Digestive 0.991 0.948 – 1.04 0.682 2150 21094 all phecode
537 Other disorders of stomach and duodenum Digestive 1.01 0.972 – 1.05 0.661 3183 30048 all phecode
537.1 Lesions of stomach and duodenum Digestive 1.08 0.927 – 1.26 0.321 173 1725 all phecode
539 Bariatric surgery Digestive 0.964 0.913 – 1.02 0.185 1509 15074 all phecode
540 Appendiceal conditions Digestive 0.964 0.877 – 1.06 0.443 495 4948 all phecode
540.1 Appendicitis Digestive 0.967 0.873 – 1.07 0.523 425 4239 all phecode
540.11 Acute appendicitis Digestive 0.957 0.856 – 1.07 0.444 353 3511 all phecode
550 Abdominal hernia Digestive 1.01 0.98 – 1.03 0.65 6768 37731 all phecode
550.1 Inguinal hernia Digestive 1.04 0.987 – 1.09 0.157 1744 16488 all phecode
550.2 Diaphragmatic hernia Digestive 0.995 0.957 – 1.03 0.789 2817 25849 all phecode
550.3 Femoral hernia Digestive 0.959 0.802 – 1.15 0.647 131 1291 all phecode
550.4 Umbilical hernia Digestive 0.99 0.934 – 1.05 0.72 1313 13110 all phecode
550.5 Ventral hernia Digestive 1.02 0.974 – 1.06 0.453 2241 22163 all phecode
550.6 Incisional hernia Digestive 1.03 0.974 – 1.09 0.298 1313 13111 all phecode
555
Inflammatory bowel disease and other
Inflammatory bowel disease and other gastroenteritis and colitis
 Digestive 1.02 0.967 – 1.07 0.489 1536 15153 all phecode
555.1 Regional enteritis Digestive 1.02 0.958 – 1.09 0.483 919 9095 all phecode
555.2 Ulcerative colitis Digestive 1.02 0.955 – 1.09 0.562 937 9315 all phecode
555.21 Ulcerative colitis (chronic) Digestive 1.04 0.951 – 1.13 0.415 537 5315 all phecode
556 Ulceration of the lower GI tract Digestive 1.08 0.997 – 1.16 0.0594 632 6267 all phecode
556.1 Ulceration of intestine Digestive 1.08 0.994 – 1.17 0.0693 551 5451 all phecode
556.11
Angiodysplasia of intestine (without mention of
Angiodysplasia of intestine (without mention of hemorrhage)
 Digestive 1.06 0.929 – 1.21 0.39 214 2093 all phecode
557 Intestinal malabsorption (non-celiac) Digestive 0.943 0.896 – 0.993 0.0249 1716 16490 all phecode
557.1 Celiac disease Digestive 0.94 0.846 – 1.04 0.245 421 4026 all phecode
558 Noninfectious gastroenteritis Digestive 1 0.966 – 1.04 0.94 3458 26408 all phecode
559 Ileostomy status Digestive 0.971 0.907 – 1.04 0.385 957 9565 all phecode
560 Intestinal obstruction without mention of hernia Digestive 0.991 0.954 – 1.03 0.632 3004 24851 all phecode
560.1 Paralytic ileus Digestive 0.994 0.945 – 1.05 0.823 1627 15714 all phecode
560.2 Impaction of intestine Digestive 0.989 0.893 – 1.09 0.829 387 3779 all phecode
560.3 Peritoneal or intestinal adhesions Digestive 0.936 0.821 – 1.07 0.316 266 2647 all phecode
560.4 Other intestinal obstruction Digestive 0.991 0.942 – 1.04 0.728 1651 16170 all phecode
561 Symptoms involving digestive system Digestive 0.978 0.939 – 1.02 0.285 2608 21766 all phecode
562 Diverticulosis and diverticulitis Digestive 1.01 0.986 – 1.04 0.33 6295 23431 all phecode
562.1 Diverticulosis Digestive 1.02 0.987 – 1.04 0.3 6246 23383 all phecode
562.2 Diverticulitis Digestive 0.989 0.939 – 1.04 0.67 1611 15162 all phecode
564 Functional digestive disorders Digestive 0.999 0.977 – 1.02 0.937 11411 28676 all phecode
564.1 Irritable Bowel Syndrome Digestive 0.992 0.957 – 1.03 0.652 3457 22266 all phecode
564.9 Personal history of diseases of digestive system Digestive 1.03 0.993 – 1.07 0.118 3074 25861 all phecode
565 Anal and rectal conditions Digestive 0.978 0.944 – 1.01 0.227 3355 30757 all phecode
565.1 Anal and rectal polyp Digestive 0.987 0.932 – 1.05 0.648 1305 12649 all phecode
567 Peritonitis and retroperitoneal infections Digestive 0.964 0.911 – 1.02 0.205 1364 13616 all phecode
568 Other disorders of peritoneum Digestive 1.03 0.985 – 1.09 0.179 1705 17038 all phecode
568.1
Peritoneal adhesions (postoperative)
Peritoneal adhesions (postoperative) (postinfection)
 Digestive 1.04 0.986 – 1.1 0.145 1247 12468 all phecode
569 Other disorders of intestine Digestive 1.01 0.986 – 1.03 0.416 8079 35231 all phecode
569.1 Toxic gastroenteritis and colitis Digestive 0.97 0.864 – 1.09 0.611 326 3260 all phecode
569.2 Gastrointestinal complications Digestive 1.03 0.974 – 1.09 0.307 1395 13933 all phecode
571 Chronic liver disease and cirrhosis Digestive 1.02 0.992 – 1.05 0.147 4610 32562 all phecode
571.5 Other chronic nonalcoholic liver disease Digestive 1.02 0.993 – 1.06 0.126 4342 32234 all phecode
571.51 Cirrhosis of liver without mention of alcohol Digestive 1.05 0.985 – 1.12 0.134 1018 10095 all phecode
571.6 Primary biliary cirrhosis Digestive 1.01 0.871 – 1.18 0.863 179 1790 all phecode
571.8
Liver abscess and sequelae of chronic liver
Liver abscess and sequelae of chronic liver disease
 Digestive 1.05 0.982 – 1.12 0.154 950 9498 all phecode
571.81 Portal hypertension Digestive 1.05 0.965 – 1.14 0.263 573 5730 all phecode
572 Ascites (non malignant) Digestive 0.984 0.942 – 1.03 0.473 2278 22675 all phecode
573 Other disorders of liver Digestive 1.03 1 – 1.06 0.0261 5599 33620 all phecode
573.1 Chronic passive congestion of liver Digestive 1.1 0.928 – 1.3 0.276 136 1359 all phecode
573.2 Liver replaced by transplant Digestive 1.05 0.934 – 1.18 0.403 292 2920 all phecode
573.3 Hepatomegaly Digestive 1.04 0.948 – 1.14 0.401 470 4700 all phecode
573.4 Acute and subacute necrosis of liver Digestive 0.98 0.872 – 1.1 0.728 316 3149 all phecode
573.5 Jaundice (not of newborn) Digestive 1 0.938 – 1.07 0.925 958 9496 all phecode
573.6
Nonspecific elevation of levels of transaminase
Nonspecific elevation of levels of transaminase or lactic acid dehydrogenase [LDH]
 Digestive 1.01 0.967 – 1.05 0.787 2756 26470 all phecode
573.7 Abnormal results of function study of liver Digestive 1.02 0.987 – 1.06 0.209 3018 27774 all phecode
573.9 Abnormal serum enzyme levels Digestive 1.02 0.985 – 1.05 0.328 4679 33866 all phecode
574 Cholelithiasis and cholecystitis Digestive 0.983 0.947 – 1.02 0.35 3177 30809 all phecode
574.1 Cholelithiasis Digestive 0.982 0.945 – 1.02 0.347 2924 28874 all phecode
574.11 Cholelithiasis with acute cholecystitis Digestive 0.959 0.855 – 1.08 0.478 342 3412 all phecode
574.12 Cholelithiasis with other cholecystitis Digestive 0.996 0.912 – 1.09 0.924 553 5501 all phecode
574.2 Calculus of bile duct Digestive 0.937 0.871 – 1.01 0.0824 852 8503 all phecode
574.3 Cholecystitis without cholelithiasis Digestive 0.998 0.928 – 1.07 0.954 822 8181 all phecode
575 Other biliary tract disease Digestive 0.986 0.945 – 1.03 0.537 2266 22555 all phecode
575.1 Cholangitis Digestive 1.05 0.941 – 1.17 0.395 354 3530 all phecode
575.2 Obstruction of bile duct Digestive 1.03 0.946 – 1.12 0.524 621 6201 all phecode
575.6 Cholesterolosis of gallbladder Digestive 0.972 0.844 – 1.12 0.698 207 2063 all phecode
575.7 Other disorders of gallbladder Digestive 0.96 0.897 – 1.03 0.241 939 9382 all phecode
575.8 Other disorders of biliary tract Digestive 1.01 0.947 – 1.07 0.831 1154 11523 all phecode
575.9
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of biliary tract
 Digestive 0.955 0.838 – 1.09 0.496 260 2600 all phecode
577 Diseases of pancreas Digestive 1 0.959 – 1.05 0.96 2225 22106 all phecode
577.1 Acute pancreatitis Digestive 0.992 0.935 – 1.05 0.791 1212 12110 all phecode
577.2 Chronic pancreatitis Digestive 0.987 0.898 – 1.08 0.782 495 4950 all phecode
577.3 Cyst and pseudocyst of pancreas Digestive 1.09 1.01 – 1.18 0.0341 570 5601 all phecode
578 Gastrointestinal hemorrhage Digestive 0.993 0.963 – 1.02 0.67 4554 37045 all phecode
578.1 Hematemesis Digestive 0.931 0.844 – 1.03 0.15 485 4842 all phecode
578.2 Blood in stool Digestive 1.01 0.968 – 1.05 0.739 2743 26554 all phecode
578.8 Hemorrhage of rectum and anus Digestive 1 0.96 – 1.05 0.894 2210 21750 all phecode
578.9 Hemorrhage of gastrointestinal tract Digestive 0.997 0.946 – 1.05 0.92 1562 15345 all phecode
579 Other symptoms involving abdomen and pelvis Digestive 0.983 0.952 – 1.01 0.288 4431 34209 all phecode
579.2 Splenomegaly Digestive 0.956 0.884 – 1.03 0.254 730 7262 all phecode
579.8 Nonspecific abnormal findings in stool contents Digestive 0.977 0.925 – 1.03 0.421 1410 13877 all phecode
580 Nephritis; nephrosis; renal sclerosis Genitourinary 0.977 0.931 – 1.03 0.365 1881 15516 all phecode
580.1 Glomerulonephritis Genitourinary 0.962 0.866 – 1.07 0.474 401 3992 all phecode
580.11 Proliferative glomerulonephritis Genitourinary 1.06 0.902 – 1.25 0.469 146 1440 all phecode
580.12 Non-proliferative glomerulonephritis Genitourinary 1.06 0.884 – 1.28 0.519 114 1128 all phecode
580.13 Acute glomerulonephritis, NOS Genitourinary 0.943 0.724 – 1.23 0.664 61 600 all phecode
580.14 Chronic glomerulonephritis, NOS Genitourinary 0.983 0.868 – 1.11 0.781 277 2760 all phecode
580.2
Nephrotic syndrome without mention of
Nephrotic syndrome without mention of glomerulonephritis
 Genitourinary 0.951 0.82 – 1.1 0.503 221 2193 all phecode
580.3
Nephritis and nephropathy without mention of
Nephritis and nephropathy without mention of glomerulonephritis
 Genitourinary 0.991 0.938 – 1.05 0.744 1502 11930 all phecode
580.31
Nephritis and nephropathy in diseases
Nephritis and nephropathy in diseases classified elsewhere
 Genitourinary 0.993 0.929 – 1.06 0.848 992 7228 all phecode
580.32
Nephritis and nephropathy with pathological
Nephritis and nephropathy with pathological lesion
 Genitourinary 0.995 0.919 – 1.08 0.895 683 6612 all phecode
580.4 Renal sclerosis, NOS Genitourinary 0.98 0.875 – 1.1 0.724 340 3400 all phecode
585 Renal failure Genitourinary 0.991 0.966 – 1.02 0.514 7470 32340 all phecode
585.1 Acute renal failure Genitourinary 0.996 0.964 – 1.03 0.807 4265 27230 all phecode
585.2 Renal failure NOS Genitourinary 0.982 0.915 – 1.05 0.616 832 8162 all phecode
585.3 Chronic renal failure [CKD] Genitourinary 0.989 0.96 – 1.02 0.443 5580 29470 all phecode
585.31 Renal dialysis Genitourinary 0.969 0.897 – 1.05 0.435 747 7423 all phecode
585.32 End stage renal disease Genitourinary 0.979 0.916 – 1.05 0.52 1007 9783 all phecode
585.33 Chronic Kidney Disease, Stage III Genitourinary 0.985 0.949 – 1.02 0.445 3209 21312 all phecode
585.34 Chronic Kidney Disease, Stage IV Genitourinary 0.947 0.885 – 1.01 0.11 977 9190 all phecode
585.4 Chronic kidney disease, Stage I or II Genitourinary 0.981 0.924 – 1.04 0.525 1227 11191 all phecode
586 Other disorders of the kidney and ureters Genitourinary 0.997 0.972 – 1.02 0.824 7628 34189 all phecode
586.1 Anatomical abnormatilies of kidney and ureters Genitourinary 0.96 0.858 – 1.07 0.471 349 3480 all phecode
586.11 Small kidney Genitourinary 0.951 0.822 – 1.1 0.5 210 2093 all phecode
586.12 Vesicoureteral reflux Genitourinary 0.936 0.785 – 1.12 0.46 136 1360 all phecode
586.2 Cyst of kidney, acquired Genitourinary 1.02 0.965 – 1.08 0.499 1381 12912 all phecode
586.3 Vascular disorders of kidney/hypertrophy Genitourinary 0.934 0.799 – 1.09 0.386 187 1862 all phecode
586.4 Stricture/obstruction of ureter Genitourinary 1.02 0.969 – 1.07 0.501 1821 17115 all phecode
587 Kidney replaced by transpant Genitourinary 0.989 0.92 – 1.06 0.76 819 8134 all phecode
588 Disorders resulting from impaired renal function Genitourinary 1 0.94 – 1.07 0.907 976 9389 all phecode
588.1 Renal osteodystrophy Genitourinary 1.01 0.897 – 1.14 0.833 290 2900 all phecode
588.2 Secondary hyperparathyroidism (of renal origin) Genitourinary 0.989 0.917 – 1.07 0.763 755 7275 all phecode
589 Abnormal results of function study of kidney Genitourinary 0.987 0.925 – 1.05 0.703 1007 9834 all phecode
590 Pyelonephritis Genitourinary 0.976 0.924 – 1.03 0.383 1461 14350 all phecode
591 Urinary tract infection Genitourinary 0.993 0.97 – 1.02 0.548 9873 32513 all phecode
592 Cystitis and urethritis Genitourinary 0.958 0.921 – 0.995 0.0283 3038 24207 all phecode
592.1 Cystitis Genitourinary 0.957 0.92 – 0.996 0.0297 2880 23279 all phecode
592.11 Acute cystitis Genitourinary 0.957 0.91 – 1.01 0.0827 1783 16452 all phecode
592.12 Chronic cystitis Genitourinary 1.06 0.93 – 1.2 0.402 239 2343 all phecode
592.13 Chronic interstitial cystitis Genitourinary 0.919 0.83 – 1.02 0.106 431 4310 all phecode
592.2 Urethritis and urethral syndrome Genitourinary 0.976 0.843 – 1.13 0.747 210 2093 all phecode
593 Hematuria Genitourinary 1 0.97 – 1.03 0.999 4859 32063 all phecode
593.1 Gross hematuria Genitourinary 0.953 0.904 – 1 0.0743 1585 14824 all phecode
593.2 Microscopic hematuria Genitourinary 0.994 0.933 – 1.06 0.841 1049 10301 all phecode
594 Urinary calculus Genitourinary 1.01 0.989 – 1.04 0.263 6707 38209 all phecode
594.1 Calculus of kidney Genitourinary 1.01 0.984 – 1.04 0.447 6273 38051 all phecode
594.2 Calculus of lower urinary tract Genitourinary 0.973 0.872 – 1.09 0.623 366 3638 all phecode
594.3 Calculus of ureter Genitourinary 0.987 0.934 – 1.04 0.652 1361 13561 all phecode
594.8 Renal colic Genitourinary 1.02 0.913 – 1.13 0.778 356 3560 all phecode
595 Hydronephrosis Genitourinary 0.963 0.915 – 1.01 0.144 1670 16658 all phecode
596 Other disorders of bladder Genitourinary 1.01 0.973 – 1.05 0.616 3074 28020 all phecode
596.1 Bladder neck obstruction Genitourinary 1.01 0.914 – 1.12 0.828 400 3942 all phecode
596.5 Functional disorders of bladder Genitourinary 0.981 0.933 – 1.03 0.44 1719 17049 all phecode
597 Other disorders of urethra and urinary tract Genitourinary 1.03 0.976 – 1.1 0.251 1211 11998 all phecode
597.1 Urethral stricture (not specified as infectious) Genitourinary 1.05 0.967 – 1.13 0.267 661 6537 all phecode
597.2 Urinary complications NEC Genitourinary 0.989 0.927 – 1.05 0.735 1049 10479 all phecode
597.8 Urethral hypermobility/ISD Genitourinary 1.13 0.983 – 1.29 0.0877 189 1873 all phecode
598 Abnormal findings on examination of urine Genitourinary 0.917 0.769 – 1.09 0.335 138 1356 all phecode
598.4 Other cells and casts in urine Genitourinary 0.896 0.74 – 1.09 0.262 122 1192 all phecode
599 Other symptoms/disorders or the urinary system Genitourinary 0.998 0.978 – 1.02 0.826 14168 30681 all phecode
599.1 Urinary obstruction Genitourinary 0.969 0.896 – 1.05 0.42 728 6861 all phecode
599.2 Retention of urine Genitourinary 1 0.97 – 1.03 0.983 5034 28305 all phecode
599.3 Dysuria Genitourinary 0.98 0.948 – 1.01 0.21 4397 27849 all phecode
599.4 Urinary incontinence Genitourinary 1 0.975 – 1.03 0.777 5599 26960 all phecode
599.5 Frequency of urination and polyuria Genitourinary 0.987 0.959 – 1.02 0.391 5498 28723 all phecode
599.6 Oliguria and anuria Genitourinary 1 0.92 – 1.09 0.993 599 5902 all phecode
599.7 Urethral discharge Genitourinary 0.885 0.72 – 1.09 0.246 118 1175 all phecode
599.8 Other symptoms involving urinary system Genitourinary 0.997 0.968 – 1.03 0.823 5446 27963 all phecode
599.9 Other abnormality of urination Genitourinary 0.971 0.934 – 1.01 0.134 3041 24877 all phecode
600 Hyperplasia of prostate Genitourinary 0.997 0.96 – 1.04 0.895 4063 11364 all phecode
601 Inflammatory diseases of prostate Genitourinary 0.993 0.931 – 1.06 0.842 1044 9665 all phecode
601.1 Prostatitis Genitourinary 0.972 0.884 – 1.07 0.563 477 4596 all phecode
601.11 Acute prostatitis Genitourinary 0.957 0.794 – 1.15 0.648 124 1200 all phecode
601.12 Chronic prostatitis Genitourinary 0.937 0.752 – 1.17 0.563 95 943 all phecode
601.3 Orchitis and epididymitis Genitourinary 1 0.904 – 1.11 0.952 389 3822 all phecode
601.4 Balanoposthitis Genitourinary 0.924 0.763 – 1.12 0.416 127 1224 all phecode
601.8
Other inflammatory disorders of male genital
Other inflammatory disorders of male genital organs
 Genitourinary 1.05 0.911 – 1.22 0.477 161 1591 all phecode
602 Other disorders of prostate Genitourinary 1.01 0.907 – 1.12 0.877 361 3399 all phecode
602.3 Dysplasia of prostate Genitourinary 0.925 0.723 – 1.18 0.534 77 730 all phecode
603 Other disorders of testis Genitourinary 1.03 0.933 – 1.13 0.582 440 4354 all phecode
603.1 Hydrocele Genitourinary 0.998 0.887 – 1.12 0.967 293 2882 all phecode
603.2 Spermatocele Genitourinary 1.05 0.892 – 1.23 0.565 156 1539 all phecode
604 Disorders of penis Genitourinary 0.953 0.879 – 1.03 0.25 685 6748 all phecode
604.1 Redundant prepuce and phimosis/BXO Genitourinary 1.04 0.881 – 1.23 0.64 155 1540 all phecode
604.3 Peyronie's disease Genitourinary 0.954 0.823 – 1.1 0.527 215 2132 all phecode
605 Erectile dysfunction [ED] Genitourinary 1.01 0.973 – 1.05 0.611 3776 12700 all phecode
608 Other disorders of male genital organs Genitourinary 1.01 0.958 – 1.06 0.752 1645 13758 all phecode
609 Male infertility and abnormal spermatozoa Genitourinary 1.02 0.922 – 1.12 0.735 424 4196 all phecode
609.1 Infertility, male Genitourinary 1.07 0.952 – 1.19 0.264 302 2992 all phecode
609.11 Azoospermia and oligospermia Genitourinary 1.06 0.86 – 1.31 0.573 95 950 all phecode
609.2 Abnormal spermatozoa Genitourinary 0.936 0.787 – 1.11 0.454 154 1519 all phecode
610 Benign mammary dysplasias Genitourinary 1 0.965 – 1.04 0.994 3683 16548 all phecode
610.1 Cystic mastopathy Genitourinary 0.998 0.949 – 1.05 0.935 1633 14191 all phecode
610.2 Fibroadenosis of breast Genitourinary 1.14 0.888 – 1.46 0.308 60 600 all phecode
610.4 Benign neoplasm of breast Genitourinary 0.999 0.96 – 1.04 0.944 2837 16430 all phecode
610.8 Other specified benign mammary dysplasias Genitourinary 1.01 0.956 – 1.07 0.695 1269 12191 all phecode
611 Abnormal findings on mammogram or breast exam Genitourinary 1.01 0.977 – 1.04 0.705 6067 18690 all phecode
611.1 Abnormal mammogram Genitourinary 1 0.969 – 1.03 0.984 4980 16120 all phecode
611.11 Mammographic microcalcification Genitourinary 1.02 0.962 – 1.09 0.471 1122 10394 all phecode
611.3 Lump or mass in breast Genitourinary 1.01 0.971 – 1.04 0.705 3549 18572 all phecode
612
Breast conditions, congenital or relating to
Breast conditions, congenital or relating to hormones
 Genitourinary 0.96 0.9 – 1.02 0.214 1051 10425 all phecode
612.1 Galactorrhea Genitourinary 0.994 0.841 – 1.18 0.946 139 1390 all phecode
612.2 Hypertrophy of breast (Gynecomastia) Genitourinary 0.944 0.876 – 1.02 0.126 800 7962 all phecode
612.3 Congenital anomalies of breast Genitourinary 0.883 0.707 – 1.1 0.269 83 810 all phecode
613 Other nonmalignant breast conditions Genitourinary 1.01 0.975 – 1.04 0.604 3897 22072 all phecode
613.1 Inflammatory disease of breast Genitourinary 1.04 0.96 – 1.13 0.328 593 5874 all phecode
613.5 Mastodynia Genitourinary 0.976 0.928 – 1.03 0.355 1675 16203 all phecode
613.7 Other signs and symptoms in breast Genitourinary 0.996 0.929 – 1.07 0.902 883 8754 all phecode
613.8 Other specified disorders of breast Genitourinary 1.04 0.974 – 1.11 0.24 932 9248 all phecode
613.9 Breast disorder NOS Genitourinary 1.07 1.01 – 1.12 0.0158 1465 14174 all phecode
614 Inflammatory diseases of female pelvic organs Genitourinary 0.998 0.963 – 1.03 0.9 3715 19647 all phecode
614.1
Pelvic peritoneal adhesions, female
Pelvic peritoneal adhesions, female (postoperative) (postinfection)
 Genitourinary 0.946 0.841 – 1.06 0.347 337 3370 all phecode
614.3 Pelvic inflammatory disease (PID) Genitourinary 0.944 0.857 – 1.04 0.237 478 4773 all phecode
614.31 Acute inflammatory pelvic disease Genitourinary 0.991 0.807 – 1.22 0.931 94 933 all phecode
614.32 Chronic inflammatory pelvic disease Genitourinary 0.925 0.793 – 1.08 0.32 186 1842 all phecode
614.33 Pelvic inflammatory disease, NOS Genitourinary 0.934 0.817 – 1.07 0.322 246 2460 all phecode
614.4 Inflammatory diseases of uterus, except cervix Genitourinary 0.986 0.842 – 1.15 0.855 165 1639 all phecode
614.5
Inflammatory disease of cervix, vagina, and
Inflammatory disease of cervix, vagina, and vulva
 Genitourinary 1.01 0.974 – 1.05 0.56 3180 19539 all phecode
614.51 Cervicitis and endocervicitis Genitourinary 1.08 0.96 – 1.22 0.2 264 2640 all phecode
614.52 Vaginitis and vulvovaginitis Genitourinary 1 0.962 – 1.04 0.938 2732 18924 all phecode
614.53 Cyst or abscess of Bartholin's gland Genitourinary 1.04 0.882 – 1.23 0.621 132 1311 all phecode
614.54 Abscess or ulceration of vulva Genitourinary 1.08 0.954 – 1.23 0.221 225 2244 all phecode
615 Endometriosis Genitourinary 0.957 0.908 – 1.01 0.102 1585 14666 all phecode
618 Genital prolapse Genitourinary 0.997 0.952 – 1.04 0.881 2079 17915 all phecode
618.1 Prolapse of vaginal walls Genitourinary 0.955 0.903 – 1.01 0.103 1408 13456 all phecode
618.2 Uterine/Uterovaginal prolapse Genitourinary 0.962 0.88 – 1.05 0.387 542 5390 all phecode
618.5 Prolapse of vaginal vault after hysterectomy Genitourinary 0.962 0.853 – 1.09 0.527 317 3162 all phecode
618.6 Vaginal enterocele, congenital or acquired Genitourinary 1.03 0.941 – 1.14 0.49 441 4394 all phecode
619 Noninflammatory female genital disorders Genitourinary 0.975 0.947 – 1 0.102 5728 18687 all phecode
619.1
Noninflammatory disorders of ovary, fallopian
Noninflammatory disorders of ovary, fallopian tube, and broad ligament
 Genitourinary 0.928 0.873 – 0.986 0.0153 1233 12082 all phecode
619.2 Disorders of uterus, NEC Genitourinary 0.932 0.854 – 1.02 0.109 591 5897 all phecode
619.3 Noninflammatory disorders of cervix Genitourinary 1.01 0.925 – 1.11 0.769 483 4823 all phecode
619.4 Noninflammatory disorders of vagina Genitourinary 0.993 0.953 – 1.04 0.756 2525 18404 all phecode
619.5 Noninflammatory disorders of vulva and perineum Genitourinary 1.01 0.951 – 1.07 0.798 1189 11717 all phecode
620 Dysplasia of female genital organs Genitourinary 1.01 0.914 – 1.12 0.843 395 3950 all phecode
620.1 Dysplasia of cervix Genitourinary 0.987 0.851 – 1.15 0.863 178 1780 all phecode
621 Endometrial hyperplasia Genitourinary 1.02 0.93 – 1.13 0.641 437 4370 all phecode
622 Polyp of female genital organs Genitourinary 0.969 0.918 – 1.02 0.254 1449 14264 all phecode
622.1 Polyp of corpus uteri Genitourinary 0.965 0.907 – 1.03 0.251 1132 11189 all phecode
622.2 Mucous polyp of cervix Genitourinary 0.966 0.878 – 1.06 0.488 445 4444 all phecode
623 Hypertrophy of female genital organs Genitourinary 1 0.935 – 1.08 0.923 824 8165 all phecode
624 Symptoms involving female genital tract Genitourinary 0.988 0.934 – 1.04 0.661 1348 12518 all phecode
624.1 Dystrophy of female genital tract Genitourinary 1.02 0.9 – 1.17 0.716 216 2155 all phecode
624.2 Atrophy of female genital tract Genitourinary 1.03 0.803 – 1.31 0.838 64 615 all phecode
624.9 stress incontinence, female Genitourinary 1 0.955 – 1.05 0.962 1935 15408 all phecode
625
Pain and other symptoms associated with female
Pain and other symptoms associated with female genital organs
 Genitourinary 0.956 0.928 – 0.986 0.00413 5653 17303 all phecode
625.1 Dyspareunia Genitourinary 0.962 0.908 – 1.02 0.194 1267 12474 all phecode
626
Disorders of menstruation and other abnormal
Disorders of menstruation and other abnormal bleeding from female genital tract
 Genitourinary 0.959 0.93 – 0.989 0.0082 5940 15585 all phecode
626.1 Irregular menstrual cycle/bleeding Genitourinary 0.957 0.924 – 0.991 0.0143 4315 14604 all phecode
626.11 Absent or infrequent menstruation Genitourinary 0.95 0.89 – 1.01 0.124 1062 8531 all phecode
626.12 Excessive or frequent menstruation Genitourinary 0.935 0.891 – 0.98 0.0055 2097 11991 all phecode
626.13 Irregular menstrual cycle Genitourinary 0.981 0.935 – 1.03 0.439 1957 12265 all phecode
626.14 Irregular menstrual bleeding Genitourinary 0.993 0.93 – 1.06 0.836 970 8996 all phecode
626.15 Infertility, female, associated with anovulation Genitourinary 0.957 0.862 – 1.06 0.41 394 3789 all phecode
626.2 Dysmenorrhea Genitourinary 0.947 0.894 – 1 0.0634 1373 9857 all phecode
626.4 Premenstrual tension syndromes Genitourinary 0.912 0.811 – 1.02 0.121 336 3308 all phecode
626.8 Infertility, female Genitourinary 0.949 0.882 – 1.02 0.167 817 6741 all phecode
627 Menopausal and postmenopausal disorders Genitourinary 0.968 0.936 – 1 0.0555 4560 14557 all phecode
627.1 Postmenopausal bleeding Genitourinary 0.965 0.908 – 1.03 0.261 1146 10338 all phecode
627.2 Symptomatic menopause Genitourinary 0.979 0.941 – 1.02 0.287 3017 13763 all phecode
627.21 Symptomatic artificial menopause Genitourinary 1.1 0.941 – 1.28 0.236 152 1514 all phecode
627.22
Need for Hormone replacement therapy
Need for Hormone replacement therapy (postmenopausal)
 Genitourinary 1 0.903 – 1.12 0.948 356 3513 all phecode
627.3 Postmenopausal atrophic vaginitis Genitourinary 0.989 0.927 – 1.06 0.741 997 9484 all phecode
627.4 Premenopausal menorrhagia Genitourinary 0.904 0.809 – 1.01 0.0739 361 3580 all phecode
627.5 Premature menopause and other ovarian failure Genitourinary 0.94 0.834 – 1.06 0.319 309 3082 all phecode
628 Ovarian cyst Genitourinary 0.936 0.892 – 0.983 0.00804 1945 13838 all phecode
634 Miscarriage; stillbirth Pregnancy Complications 1.01 0.937 – 1.08 0.868 826 8047 all phecode
634.1 Missed abortion/Hydatidiform mole Pregnancy Complications 0.981 0.864 – 1.11 0.766 273 2715 all phecode
634.3 Ectopic pregnancy Pregnancy Complications 1.1 0.928 – 1.31 0.268 117 1170 all phecode
635
Hemorrhage during pregnancy; childbirth and
Hemorrhage during pregnancy; childbirth and postpartum
 Pregnancy Complications 1.08 0.988 – 1.17 0.0905 563 5309 all phecode
635.2
Antepartum hemorrhage, abruptio placentae, and
Antepartum hemorrhage, abruptio placentae, and placenta previa
 Pregnancy Complications 1.14 1.03 – 1.26 0.0102 370 3629 all phecode
635.3 Placenta previa and abruptio placenta Pregnancy Complications 0.999 0.888 – 1.13 0.993 288 2850 all phecode
636
Early or threatened labor; hemorrhage in early
Early or threatened labor; hemorrhage in early pregnancy
 Pregnancy Complications 1.03 0.963 – 1.09 0.438 1080 7870 all phecode
636.1 Threatened premature labor Pregnancy Complications 1.06 0.955 – 1.17 0.281 380 3799 all phecode
636.2 Early onset of delivery Pregnancy Complications 1.02 0.904 – 1.15 0.758 288 2868 all phecode
636.3 Hemorrhage in early pregnancy Pregnancy Complications 1.05 0.952 – 1.15 0.346 441 4365 all phecode
636.8 Cervical incompetence Pregnancy Complications 1.15 0.929 – 1.42 0.198 77 770 all phecode
637
Short gestation; low birth weight; and fetal
Short gestation; low birth weight; and fetal growth retardation
 Pregnancy Complications 0.757 0.592 – 0.969 0.0272 85 850 all phecode
642
Hypertension complicating pregnancy
Hypertension complicating pregnancy, childbirth, and the puerperium
 Pregnancy Complications 0.998 0.916 – 1.09 0.96 585 5725 all phecode
642.1 Preeclampsia and eclampsia Pregnancy Complications 0.928 0.818 – 1.05 0.243 302 3013 all phecode
643 Excessive vomiting in pregnancy Pregnancy Complications 1.03 0.903 – 1.17 0.695 252 2506 all phecode
643.1 Hyperemesis gravidarum Pregnancy Complications 1.1 0.916 – 1.31 0.314 119 1190 all phecode
644 Anemia during pregnancy Pregnancy Complications 1.11 0.98 – 1.27 0.0992 224 2224 all phecode
646 Other complications of pregnancy NEC Pregnancy Complications 1.03 0.962 – 1.11 0.375 855 6531 all phecode
647
Infectious and parasitic complications
Infectious and parasitic complications affecting pregnancy
 Pregnancy Complications 1.22 1.08 – 1.39 0.00163 211 2093 all phecode
647.1
Infections of genitourinary tract during
Infections of genitourinary tract during pregnancy
 Pregnancy Complications 1.09 0.95 – 1.24 0.229 222 2213 all phecode
647.3 Major puerperal infection Pregnancy Complications 1.14 0.892 – 1.44 0.302 65 650 all phecode
649
Other conditions or status of the mother
Other conditions or status of the mother complicating pregnancy, childbirth, or the puerperium
 Pregnancy Complications 1.04 0.981 – 1.1 0.192 1275 8010 all phecode
649.1
Diabetes or abnormal glucose tolerance
Diabetes or abnormal glucose tolerance complicating pregnancy
 Pregnancy Complications 0.98 0.903 – 1.06 0.633 649 5687 all phecode
653
Problems associated with amniotic cavity and
Problems associated with amniotic cavity and membranes
 Pregnancy Complications 1.16 1.07 – 1.25 0.000297 587 5463 all phecode
654.1
Abnormality of organs and soft tissues of
Abnormality of organs and soft tissues of pelvis complicating pregnancy, childbirth, or the puerperium
 Pregnancy Complications 1.1 0.957 – 1.26 0.186 207 2055 all phecode
654.2 Rhesus isoimmunization in pregnancy Pregnancy Complications 1.13 0.983 – 1.29 0.0864 204 2040 all phecode
655
Known or suspected fetal abnormality affecting
Known or suspected fetal abnormality affecting management of mother
 Pregnancy Complications 1.01 0.962 – 1.07 0.617 1624 10064 all phecode
655.1 Abnormality in fetal heart rate or rhythm Pregnancy Complications 1.03 0.948 – 1.12 0.488 616 5533 all phecode
656 Other perinatal conditions of fetus or newborn Pregnancy Complications 1.01 0.939 – 1.08 0.849 898 7014 all phecode
656.2 Respiratory conditions of fetus and newborn Pregnancy Complications 0.99 0.768 – 1.28 0.938 66 660 all phecode
669 Complications of labor and delivery NEC Pregnancy Complications 1.01 0.945 – 1.09 0.72 887 6802 all phecode
671
Venous/cerebrovascular complications embolism
Venous/cerebrovascular complications embolism in pregnancy and the puerperium
 Pregnancy Complications 1.05 0.917 – 1.19 0.503 236 2351 all phecode
674 Other complications of the puerperium NEC Pregnancy Complications 0.895 0.757 – 1.06 0.197 158 1580 all phecode
676
Other disorders of the breast associated with
Other disorders of the breast associated with childbirth and disorders of lactation
 Pregnancy Complications 0.997 0.856 – 1.16 0.964 184 1814 all phecode
681 Superficial cellulitis and abscess Dermatologic 1.02 0.989 – 1.04 0.251 6500 38394 all phecode
681.1 Cellulitis and abscess of fingers/toes Dermatologic 1.06 0.998 – 1.12 0.0604 1256 11462 all phecode
681.2 Cellulitis and abscess of face/neck Dermatologic 1.02 0.961 – 1.09 0.472 1007 9981 all phecode
681.3 Cellulitis and abscess of arm/hand Dermatologic 1.03 0.99 – 1.08 0.128 2123 19952 all phecode
681.5 Cellulitis and abscess of leg, except foot Dermatologic 1.03 0.986 – 1.07 0.182 2252 20944 all phecode
681.6 Cellulitis and abscess of foot, toe Dermatologic 1.02 0.968 – 1.07 0.522 1820 16893 all phecode
681.7 Cellulitis and abscess of trunk Dermatologic 0.985 0.935 – 1.04 0.575 1572 15588 all phecode
686
Other local infections of skin and subcutaneous
Other local infections of skin and subcutaneous tissue
 Dermatologic 0.996 0.954 – 1.04 0.868 2257 21750 all phecode
686.1 Carbuncle and furuncle Dermatologic 1.02 0.941 – 1.11 0.586 558 5504 all phecode
686.2 Impetigo Dermatologic 1.02 0.924 – 1.13 0.698 414 4117 all phecode
686.3 Pilonidal cyst Dermatologic 1.05 0.897 – 1.23 0.542 160 1594 all phecode
686.4 Pyogenic granuloma Dermatologic 1.02 0.869 – 1.19 0.831 158 1570 all phecode
686.5 Pyoderma Dermatologic 0.905 0.684 – 1.2 0.487 63 630 all phecode
687 Symptoms affecting skin Dermatologic 0.978 0.93 – 1.03 0.393 1690 16343 all phecode
687.1 Rash and other nonspecific skin eruption Dermatologic 0.996 0.97 – 1.02 0.735 7007 34623 all phecode
687.3 Changes in skin texture Dermatologic 0.965 0.874 – 1.07 0.489 415 4121 all phecode
687.4 Disturbance of skin sensation Dermatologic 1.01 0.985 – 1.04 0.408 6375 34216 all phecode
689 Disorder of skin and subcutaneous tissue NOS Dermatologic 1.01 0.989 – 1.04 0.308 9311 37335 all phecode
690 Erythematosquamous dermatosis Dermatologic 0.994 0.965 – 1.02 0.671 5184 31581 all phecode
690.1 Seborrheic dermatitis Dermatologic 0.994 0.965 – 1.02 0.677 5174 31553 all phecode
691 Congenital anomalies of skin Dermatologic 0.936 0.855 – 1.02 0.148 541 5337 all phecode
691.3 Congenital pigmentary anomalies of skin Dermatologic 0.883 0.669 – 1.16 0.377 62 613 all phecode
694 Dyschromia and Vitiligo Dermatologic 0.975 0.929 – 1.02 0.297 1861 17936 all phecode
694.1 Vitiligo Dermatologic 1.05 0.886 – 1.25 0.553 137 1347 all phecode
694.2 Other dyschromia Dermatologic 0.97 0.922 – 1.02 0.232 1674 16183 all phecode
694.3 Vascular disorders of skin Dermatologic 0.978 0.777 – 1.23 0.851 82 819 all phecode
695 Erythematous conditions Dermatologic 0.971 0.939 – 1 0.08 4120 30247 all phecode
695.1 Toxic erythema Dermatologic 0.905 0.7 – 1.17 0.444 70 688 all phecode
695.2 Bullous dermatoses Dermatologic 1.12 0.918 – 1.36 0.268 85 805 all phecode
695.3 Rosacea Dermatologic 0.992 0.945 – 1.04 0.745 1816 17663 all phecode
695.4 Lupus (localized and systemic) Dermatologic 0.959 0.885 – 1.04 0.307 672 6686 all phecode
695.41 Cutaneous lupus erythematosus Dermatologic 0.942 0.823 – 1.08 0.38 247 2437 all phecode
695.42 Systemic lupus erythematosus Dermatologic 0.953 0.877 – 1.04 0.264 637 6337 all phecode
695.7 Prurigo and Lichen Dermatologic 0.976 0.897 – 1.06 0.562 605 5986 all phecode
695.8 Other specified erythematous conditions Dermatologic 0.936 0.869 – 1.01 0.0793 812 7980 all phecode
695.81 Erythema nodosum Dermatologic 0.958 0.727 – 1.26 0.763 55 550 all phecode
695.9 Unspecified erythematous condition Dermatologic 0.983 0.908 – 1.06 0.67 679 6756 all phecode
696 Psoriasis and related disorders Dermatologic 0.947 0.895 – 1 0.0551 1401 13832 all phecode
696.3 Pityriasis Dermatologic 0.898 0.718 – 1.12 0.345 92 904 all phecode
696.4 Psoriasis Dermatologic 0.953 0.9 – 1.01 0.1 1311 12976 all phecode
696.41 Psoriasis vulgaris Dermatologic 0.952 0.897 – 1.01 0.109 1200 11867 all phecode
696.42 Psoriatic arthropathy Dermatologic 0.909 0.801 – 1.03 0.136 282 2810 all phecode
697 Sarcoidosis Dermatologic 0.996 0.889 – 1.12 0.945 333 3330 all phecode
698 Pruritus and related conditions Dermatologic 0.973 0.932 – 1.02 0.215 2254 21889 all phecode
700 Corns and callosities Dermatologic 1.04 0.983 – 1.1 0.177 1373 10894 all phecode
701
Other hypertrophic and atrophic conditions of
Other hypertrophic and atrophic conditions of skin
 Dermatologic 0.996 0.972 – 1.02 0.748 7651 38050 all phecode
701.1 Keratoderma, acquired Dermatologic 1.06 0.982 – 1.16 0.13 567 5524 all phecode
701.2 Scar conditions and fibrosis of skin Dermatologic 1.02 0.977 – 1.07 0.352 2184 21550 all phecode
701.3 Circumscribed scleroderma Dermatologic 0.99 0.908 – 1.08 0.812 571 5660 all phecode
701.4 Keloid scar Dermatologic 1.03 0.95 – 1.12 0.453 578 5716 all phecode
701.5 Abnormal granulation tissue Dermatologic 1.03 0.931 – 1.14 0.552 400 3982 all phecode
702
Degenerative skin conditions and other
Degenerative skin conditions and other dermatoses
 Dermatologic 1.01 0.983 – 1.04 0.485 6956 29525 all phecode
702.1 Actinic keratosis Dermatologic 1.01 0.977 – 1.04 0.573 4171 26529 all phecode
702.2 Seborrheic keratosis Dermatologic 1.01 0.981 – 1.04 0.515 5480 31552 all phecode
702.4 Degenerative skin disorders Dermatologic 0.887 0.707 – 1.11 0.301 86 832 all phecode
703 Diseases of nail, NOS Dermatologic 1.02 0.967 – 1.07 0.52 1650 14562 all phecode
703.1 Ingrowing nail Dermatologic 1.05 0.985 – 1.13 0.126 920 8597 all phecode
704 Diseases of hair and hair follicles Dermatologic 1.01 0.975 – 1.05 0.563 3118 29542 all phecode
704.1 Alopecia Dermatologic 1 0.95 – 1.06 0.935 1408 13871 all phecode
704.11 Alopecia Areata Dermatologic 1.22 0.997 – 1.5 0.0533 82 811 all phecode
704.12 Telogen effluvium Dermatologic 1.01 0.801 – 1.28 0.918 63 615 all phecode
704.2 Hirsutism Dermatologic 0.943 0.838 – 1.06 0.332 299 2946 all phecode
704.8
Other specified diseases of hair and hair
Other specified diseases of hair and hair follicles
 Dermatologic 1.02 0.97 – 1.07 0.479 1752 17189 all phecode
705 Disorders of sweat glands Dermatologic 1.03 0.944 – 1.11 0.548 603 6012 all phecode
705.1 Dyshidrosis Dermatologic 0.949 0.799 – 1.13 0.546 154 1540 all phecode
705.3 Hidradenitis Dermatologic 1.03 0.906 – 1.16 0.675 245 2440 all phecode
705.8 Hyperhidrosis Dermatologic 1.02 0.956 – 1.08 0.613 1112 10986 all phecode
706 Diseases of sebaceous glands Dermatologic 1 0.977 – 1.03 0.753 5995 39748 all phecode
706.1 Acne Dermatologic 0.999 0.959 – 1.04 0.976 2594 22570 all phecode
706.2 Sebaceous cyst Dermatologic 0.987 0.949 – 1.03 0.5 2814 26819 all phecode
706.3 Seborrhea Dermatologic 0.941 0.73 – 1.21 0.64 59 582 all phecode
706.8 Other specified diseases of sebaceous glands Dermatologic 1.01 0.964 – 1.06 0.618 1684 15289 all phecode
707 Chronic ulcer of skin Dermatologic 1.01 0.974 – 1.05 0.542 2871 26816 all phecode
707.1 Decubitus ulcer Dermatologic 1 0.932 – 1.07 0.981 825 8119 all phecode
707.2 Chronic ulcer of leg or foot Dermatologic 1.04 0.975 – 1.1 0.248 1108 9992 all phecode
707.3 Chronic ulcer of unspecified site Dermatologic 0.982 0.934 – 1.03 0.497 1641 16172 all phecode
709 Diffuse diseases of connective tissue Dermatologic 0.978 0.927 – 1.03 0.417 1477 14427 all phecode
709.2 Sicca syndrome Dermatologic 0.981 0.894 – 1.08 0.696 505 4986 all phecode
709.3 Systemic sclerosis Dermatologic 0.923 0.801 – 1.06 0.27 224 2209 all phecode
709.5 Dermatomyositis Dermatologic 0.874 0.699 – 1.09 0.241 92 892 all phecode
709.6
Other specified diffuse diseases of connective
Other specified diffuse diseases of connective tissue
 Dermatologic 1.03 0.846 – 1.26 0.742 90 892 all phecode
709.7 Unspecified diffuse connective tissue disease Dermatologic 0.967 0.903 – 1.04 0.332 917 9089 all phecode
710
Osteomyelitis, periostitis, and other
Osteomyelitis, periostitis, and other infections involving bone
 Musculoskeletal 1.03 0.972 – 1.09 0.337 1254 12103 all phecode
710.1 Osteomyelitis Musculoskeletal 1.03 0.97 – 1.09 0.356 1203 11636 all phecode
710.11 Acute osteomyelitis Musculoskeletal 1.05 0.965 – 1.14 0.268 590 5708 all phecode
710.12 Chronic osteomyelitis Musculoskeletal 1.02 0.936 – 1.11 0.638 531 5163 all phecode
710.19 Unspecified osteomyelitis Musculoskeletal 1.04 0.983 – 1.1 0.171 1153 11149 all phecode
711 Arthropathy associated with infections Musculoskeletal 1.01 0.911 – 1.11 0.887 410 4099 all phecode
711.1 Pyogenic arthritis Musculoskeletal 0.979 0.867 – 1.11 0.736 290 2900 all phecode
712 Infective connective tissue disorders Musculoskeletal 1.07 0.923 – 1.24 0.374 178 1776 all phecode
713
Arthropathy associated with other disorders
Arthropathy associated with other disorders classified elsewhere
 Musculoskeletal 1.05 0.939 – 1.17 0.394 314 3028 all phecode
713.5
Arthropathy associated with neurological
Arthropathy associated with neurological disorders
 Musculoskeletal 1.07 0.933 – 1.22 0.335 194 1824 all phecode
714
Rheumatoid arthritis and other inflammatory
Rheumatoid arthritis and other inflammatory polyarthropathies
 Musculoskeletal 0.991 0.947 – 1.04 0.688 2086 18159 all phecode
714.1 Rheumatoid arthritis Musculoskeletal 0.993 0.944 – 1.04 0.778 1670 15087 all phecode
714.2 Juvenile rheumatoid arthritis Musculoskeletal 0.793 0.606 – 1.04 0.0927 77 767 all phecode
715 Other inflammatory spondylopathies Musculoskeletal 1.01 0.95 – 1.07 0.811 1209 11967 all phecode
715.1 Sacroiliitis NEC Musculoskeletal 0.996 0.879 – 1.13 0.944 262 2611 all phecode
715.2 Ankylosing spondylitis Musculoskeletal 0.975 0.851 – 1.12 0.716 219 2182 all phecode
716 Other arthropathies Musculoskeletal 0.98 0.959 – 1 0.056 13482 31305 all phecode
716.1 Unspecified polyarthropathy or polyarthritis Musculoskeletal 0.879 0.755 – 1.02 0.0969 192 1920 all phecode
716.2 Unspecified monoarthritis Musculoskeletal 0.931 0.777 – 1.12 0.436 131 1293 all phecode
716.9 Arthropathy NOS Musculoskeletal 0.981 0.96 – 1 0.0724 13410 31294 all phecode
717 Polymyalgia Rheumatica Musculoskeletal 1.05 0.925 – 1.18 0.467 261 2565 all phecode
720 Spinal stenosis Musculoskeletal 0.983 0.951 – 1.02 0.326 3958 28539 all phecode
720.1 Spinal stenosis of lumbar region Musculoskeletal 0.97 0.933 – 1.01 0.129 2872 23656 all phecode
721 Spondylosis and allied disorders Musculoskeletal 0.992 0.964 – 1.02 0.582 5509 32391 all phecode
721.1 Spondylosis without myelopathy Musculoskeletal 0.991 0.962 – 1.02 0.553 5153 31896 all phecode
721.2 Spondylosis with myelopathy Musculoskeletal 1.01 0.943 – 1.09 0.745 867 8629 all phecode
721.8 Other allied disorders of spine Musculoskeletal 1.08 0.962 – 1.21 0.195 262 2600 all phecode
722 Intervertebral disc disorders Musculoskeletal 0.996 0.97 – 1.02 0.797 6284 34317 all phecode
722.1 Displacement of intervertebral disc Musculoskeletal 0.989 0.956 – 1.02 0.549 3591 31411 all phecode
722.3 Schmorl's nodes Musculoskeletal 1.04 0.867 – 1.24 0.682 126 1248 all phecode
722.6 Degeneration of intervertebral disc Musculoskeletal 0.981 0.949 – 1.01 0.259 3957 30744 all phecode
722.7 Intervertebral disc disorder with myelopathy Musculoskeletal 0.987 0.902 – 1.08 0.778 515 5140 all phecode
722.8 Postlaminectomy syndrome Musculoskeletal 0.947 0.851 – 1.05 0.317 397 3968 all phecode
722.9 Other and unspecified disc disorder Musculoskeletal 1.01 0.967 – 1.06 0.579 1932 19288 all phecode
723 Other disorders of cervical region Musculoskeletal 1.04 0.975 – 1.11 0.235 952 9495 all phecode
723.1 Torticollis Musculoskeletal 1.14 1.02 – 1.28 0.027 254 2522 all phecode
724 Other and unspecified disorders of back Musculoskeletal 0.995 0.963 – 1.03 0.748 4130 31954 all phecode
724.1 Disorders of sacrum Musculoskeletal 1 0.962 – 1.05 0.856 2307 21902 all phecode
724.2 Disorders of coccyx Musculoskeletal 1.04 0.946 – 1.14 0.425 426 4215 all phecode
724.8 Other symptoms referable to back Musculoskeletal 0.932 0.869 – 1 0.0504 931 9295 all phecode
724.9 Other unspecified back disorders Musculoskeletal 1.02 0.961 – 1.07 0.589 1412 14087 all phecode
726 Peripheral enthesopathies and allied syndromes Musculoskeletal 0.998 0.976 – 1.02 0.897 9917 30176 all phecode
726.1 Enthesopathy Musculoskeletal 0.997 0.972 – 1.02 0.821 7507 30106 all phecode
726.2 Synoviopathy Musculoskeletal 1.02 0.957 – 1.09 0.545 1015 9987 all phecode
726.3 Bursitis Musculoskeletal 0.987 0.941 – 1.04 0.611 1829 16722 all phecode
726.4 Calcaneal spur; Exostosis NOS Musculoskeletal 0.994 0.936 – 1.06 0.842 1193 11485 all phecode
727 Other disorders of synovium, tendon, and bursa Musculoskeletal 1.01 0.981 – 1.03 0.607 7425 30105 all phecode
727.1 Synovitis and tenosynovitis Musculoskeletal 0.998 0.962 – 1.04 0.936 3092 24998 all phecode
727.2 Bursitis disorders Musculoskeletal 1.05 0.954 – 1.16 0.316 419 4112 all phecode
727.4 Ganglion and cyst of synovium, tendon, and bursa Musculoskeletal 1.02 0.962 – 1.07 0.576 1400 13621 all phecode
727.5 Rupture of synovium Musculoskeletal 1.11 1.02 – 1.22 0.0198 480 4672 all phecode
727.6 Rupture of tendon, nontraumatic Musculoskeletal 1.01 0.972 – 1.06 0.544 2461 21948 all phecode
727.7 Contracture of tendon (sheath) Musculoskeletal 0.998 0.917 – 1.09 0.969 591 5893 all phecode
727.8 Plica syndrome Musculoskeletal 0.833 0.682 – 1.02 0.0726 130 1264 all phecode
728 Disorders of muscle, ligament, and fascia Musculoskeletal 1.01 0.976 – 1.04 0.667 4546 29473 all phecode
728.1 Muscular calcification and ossification Musculoskeletal 0.916 0.727 – 1.15 0.459 85 843 all phecode
728.2 Laxity of ligament or hypermobility syndrome Musculoskeletal 0.928 0.82 – 1.05 0.239 297 2949 all phecode
728.7 Fasciitis Musculoskeletal 0.999 0.96 – 1.04 0.945 2814 23463 all phecode
728.71
Contracture of palmar fascia [Dupuytren's
Contracture of palmar fascia [Dupuytren's disease]
 Musculoskeletal 1.11 1.01 – 1.22 0.0271 419 4138 all phecode
729 Other disorders of soft tissues Musculoskeletal 1.01 0.973 – 1.04 0.673 3642 27471 all phecode
729.1 Rheumatism, unspecified and fibrositis Musculoskeletal 0.902 0.695 – 1.17 0.438 74 726 all phecode
729.3 Panniculitis Musculoskeletal 0.979 0.817 – 1.17 0.822 119 1174 all phecode
729.7 Nontraumatic compartment syndrome Musculoskeletal 1.34 1.07 – 1.67 0.0104 67 664 all phecode
731
Osteitis deformans and osteopathies associated
Osteitis deformans and osteopathies associated with other disorders classified elsewhere
 Musculoskeletal 0.966 0.838 – 1.11 0.627 210 2091 all phecode
732 Osteochondropathies Musculoskeletal 1.09 0.989 – 1.21 0.081 361 3604 all phecode
732.1 Juvenile osteochondrosis Musculoskeletal 1.07 0.934 – 1.22 0.33 198 1969 all phecode
732.7 Osteochondritis dissecans Musculoskeletal 1.17 0.965 – 1.42 0.111 90 882 all phecode
733 Other disorders of bone and cartilage Musculoskeletal 0.983 0.952 – 1.01 0.294 4543 26941 all phecode
733.2 Cyst of bone Musculoskeletal 1.2 1.06 – 1.37 0.0047 190 1900 all phecode
733.4 Aseptic necrosis of bone Musculoskeletal 0.988 0.903 – 1.08 0.799 518 5160 all phecode
733.6 Costochondritis Musculoskeletal 0.967 0.867 – 1.08 0.55 357 3562 all phecode
733.8 Malunion and nonunion of fracture Musculoskeletal 0.987 0.919 – 1.06 0.72 822 8205 all phecode
733.9 Chondromalacia Musculoskeletal 0.928 0.752 – 1.15 0.487 96 960 all phecode
735 Acquired foot deformities Musculoskeletal 0.984 0.95 – 1.02 0.379 3417 29622 all phecode
735.1 Flat foot Musculoskeletal 0.96 0.883 – 1.04 0.339 620 6092 all phecode
735.2 Acquired toe deformities Musculoskeletal 0.947 0.894 – 1 0.067 1323 11983 all phecode
735.21 Hammer toe (acquired) Musculoskeletal 0.954 0.887 – 1.03 0.21 825 7494 all phecode
735.23 Hallux rigidus Musculoskeletal 0.979 0.884 – 1.08 0.68 405 4005 all phecode
735.3 Hallux valgus (Bunion) Musculoskeletal 0.949 0.898 – 1 0.0603 1470 14295 all phecode
736 Other acquired deformities of limbs Musculoskeletal 0.985 0.946 – 1.02 0.441 2763 26555 all phecode
736.1 Acquired deformities of forearm Musculoskeletal 1.06 0.869 – 1.29 0.569 104 1033 all phecode
736.2 Acquired deformities of finger Musculoskeletal 0.952 0.826 – 1.1 0.497 215 2142 all phecode
736.3 Acquired deformities of hip Musculoskeletal 1.09 0.839 – 1.42 0.516 60 590 all phecode
736.4 Genu valgum or varum (acquired) Musculoskeletal 1.12 1 – 1.24 0.0485 325 3247 all phecode
736.5 Acquired deformities of knee Musculoskeletal 1.13 0.999 – 1.27 0.0514 246 2460 all phecode
736.6 Unequal leg length (acquired) Musculoskeletal 1 0.898 – 1.12 0.978 339 3365 all phecode
737 Curvature of spine Musculoskeletal 0.94 0.891 – 0.992 0.0238 1566 15543 all phecode
737.1 Kyphosis (acquired) Musculoskeletal 0.963 0.874 – 1.06 0.444 479 4748 all phecode
737.2 Lordosis (acquired) Musculoskeletal 1.01 0.788 – 1.3 0.926 70 700 all phecode
737.3 Kyphoscoliosis and scoliosis Musculoskeletal 0.927 0.871 – 0.986 0.0156 1203 11982 all phecode
738 Other acquired musculoskeletal deformity Musculoskeletal 0.981 0.941 – 1.02 0.376 2443 24187 all phecode
738.4 Acquired spondylolisthesis Musculoskeletal 0.972 0.911 – 1.04 0.388 1057 10542 all phecode
739 Contracture of joint Musculoskeletal 0.976 0.898 – 1.06 0.573 621 6207 all phecode
740 Osteoarthrosis Musculoskeletal 0.986 0.966 – 1.01 0.168 16169 30268 all phecode
740.1 Osteoarthritis; localized Musculoskeletal 0.992 0.965 – 1.02 0.556 7005 27422 all phecode
740.11 Osteoarthrosis, localized, primary Musculoskeletal 0.993 0.965 – 1.02 0.629 6176 26155 all phecode
740.12 Osteoarthrosis, localized, secondary Musculoskeletal 1 0.928 – 1.08 0.944 713 7116 all phecode
740.2 Osteoarthrosis, generalized Musculoskeletal 1.02 0.97 – 1.08 0.417 1609 12092 all phecode
740.3
Osteoarthrosis involving more than one site
Osteoarthrosis involving more than one site, but not specified as generalized
 Musculoskeletal 0.996 0.895 – 1.11 0.946 373 3586 all phecode
740.9 Osteoarthrosis NOS Musculoskeletal 0.986 0.966 – 1.01 0.174 15497 30141 all phecode
741 Symptoms and disorders of the joints Musculoskeletal 0.988 0.965 – 1.01 0.311 8555 35884 all phecode
741.1 Ankylosis of joint Musculoskeletal 0.932 0.813 – 1.07 0.312 245 2445 all phecode
741.2 Stiffness of joint Musculoskeletal 1 0.946 – 1.06 0.961 1268 12594 all phecode
741.3 Difficulty in walking Musculoskeletal 0.987 0.948 – 1.03 0.536 2558 23116 all phecode
741.4 Joint effusions Musculoskeletal 1 0.96 – 1.04 0.984 2493 24199 all phecode
741.5 Hemarthrosis Musculoskeletal 1.03 0.837 – 1.26 0.788 94 937 all phecode
741.6 Villonodular synovitis Musculoskeletal 1.08 0.845 – 1.37 0.554 68 666 all phecode
742 Derangement of joint, non-traumatic Musculoskeletal 0.981 0.951 – 1.01 0.242 4404 33771 all phecode
742.1 Loose body in joint Musculoskeletal 0.965 0.815 – 1.14 0.683 156 1554 all phecode
742.2
Pathological, developmental or recurrent
Pathological, developmental or recurrent dislocation
 Musculoskeletal 0.97 0.855 – 1.1 0.629 280 2792 all phecode
742.8 Articular cartilage disorder Musculoskeletal 0.987 0.861 – 1.13 0.852 245 2450 all phecode
742.9 Other derangement of joint Musculoskeletal 0.987 0.956 – 1.02 0.443 4107 32972 all phecode
743
Osteoporosis, osteopenia and pathological
Osteoporosis, osteopenia and pathological fracture
 Musculoskeletal 0.978 0.955 – 1 0.0722 9223 36921 all phecode
743.1 Osteoporosis Musculoskeletal 0.986 0.951 – 1.02 0.434 3712 19477 all phecode
743.11 Osteoporosis NOS Musculoskeletal 0.986 0.95 – 1.02 0.438 3657 19276 all phecode
743.12 Senile osteoporosis Musculoskeletal 0.936 0.865 – 1.01 0.104 703 5804 all phecode
743.13 Other specified osteoporosis Musculoskeletal 0.966 0.862 – 1.08 0.554 321 3141 all phecode
743.2 Pathologic fracture Musculoskeletal 0.961 0.903 – 1.02 0.216 1112 10563 all phecode
743.21 Pathologic fracture of vertebrae Musculoskeletal 0.936 0.85 – 1.03 0.185 475 4629 all phecode
743.22 Pathologic fracture of femur Musculoskeletal 1.12 0.956 – 1.32 0.16 143 1391 all phecode
743.4 Stress fracture Musculoskeletal 0.983 0.887 – 1.09 0.738 407 4046 all phecode
743.9
Osteopenia or other disorder of bone and
Osteopenia or other disorder of bone and cartilage
 Musculoskeletal 0.977 0.951 – 1 0.0849 6970 35237 all phecode
745 Pain in joint Musculoskeletal 0.998 0.98 – 1.02 0.85 19848 26918 all phecode
747 Cardiac and circulatory congenital anomalies Congenital Anomalies 1.01 0.969 – 1.06 0.616 2236 22256 all phecode
747.1 Cardiac congenital anomalies Congenital Anomalies 1.01 0.964 – 1.06 0.645 1767 17598 all phecode
747.11 Cardiac shunt/ heart septal defect Congenital Anomalies 0.952 0.877 – 1.03 0.246 650 6497 all phecode
747.12 Valvular heart disease/ heart chambers Congenital Anomalies 1.06 0.989 – 1.14 0.0965 751 7480 all phecode
747.13 Congenital anomalies of great vessels Congenital Anomalies 1.06 0.961 – 1.17 0.24 410 4090 all phecode
747.2
Congenital anomalies of peripheral vascular
Congenital anomalies of peripheral vascular system
 Congenital Anomalies 0.977 0.891 – 1.07 0.628 501 5010 all phecode
748 Anomalies of respiratory system, congenital Congenital Anomalies 0.854 0.689 – 1.06 0.152 111 1110 all phecode
749 Congenital anomalies of face and neck Congenital Anomalies 1.05 0.962 – 1.14 0.282 555 5549 all phecode
749.1 Cleft palate Congenital Anomalies 0.986 0.798 – 1.22 0.893 97 970 all phecode
749.2 Congenital anomalies of skull and face bones Congenital Anomalies 1.11 0.927 – 1.34 0.248 105 1041 all phecode
750 Digestive congenital anomalies Congenital Anomalies 0.984 0.918 – 1.05 0.651 893 8919 all phecode
750.1 Upper gastrointestinal congenital anomalies Congenital Anomalies 1.01 0.908 – 1.12 0.887 366 3655 all phecode
750.11 Esophageal atresia/tracheoesophageal fistula Congenital Anomalies 1.02 0.849 – 1.22 0.846 119 1185 all phecode
750.13 Congenital anomalies of mouth/tongue Congenital Anomalies 0.923 0.736 – 1.16 0.488 99 982 all phecode
750.14 Congenital anomalies of esophagus Congenital Anomalies 1.06 0.907 – 1.25 0.442 134 1332 all phecode
750.15 Congenital anomalies of stomach Congenital Anomalies 0.972 0.748 – 1.26 0.83 60 593 all phecode
750.2 Lower gastrointestinal congenital anomalies Congenital Anomalies 0.955 0.87 – 1.05 0.327 531 5300 all phecode
750.21 Congenital anomalies of intestine Congenital Anomalies 0.975 0.867 – 1.1 0.681 313 3129 all phecode
750.22
Congenital anomaly of gallbladder, bile ducts
Congenital anomaly of gallbladder, bile ducts, liver, pancreas
 Congenital Anomalies 0.882 0.762 – 1.02 0.0915 222 2214 all phecode
751 Genitourinary congenital anomalies Congenital Anomalies 1 0.955 – 1.05 0.988 2008 19975 all phecode
751.1 Congenital anomalies of genital organs Congenital Anomalies 0.935 0.856 – 1.02 0.137 574 5740 all phecode
751.11 Congenital anomalies of female genital organs Congenital Anomalies 0.863 0.771 – 0.966 0.0105 384 3840 all phecode
751.12 Congenital anomalies of male genital organs Congenital Anomalies 1.07 0.911 – 1.26 0.409 153 1527 all phecode
751.2 Congenital anomalies of urinary system Congenital Anomalies 1.01 0.957 – 1.07 0.693 1379 13704 all phecode
751.21 Cystic kidney disease Congenital Anomalies 1.01 0.949 – 1.08 0.685 976 9685 all phecode
751.22 Other specified congenital anomalies of kidney Congenital Anomalies 0.931 0.823 – 1.05 0.26 294 2927 all phecode
751.3 Obstructive genitourinary defect Congenital Anomalies 1.02 0.876 – 1.18 0.832 182 1809 all phecode
752 Nervous system congenital anomalies Congenital Anomalies 0.948 0.891 – 1.01 0.0905 1133 11313 all phecode
752.1 Neural tube defects Congenital Anomalies 0.945 0.882 – 1.01 0.11 923 9209 all phecode
752.11 Spina bifida Congenital Anomalies 1.09 0.936 – 1.26 0.272 176 1760 all phecode
752.2
Other specified congenital anomalies of nervous
Other specified congenital anomalies of nervous system
 Congenital Anomalies 1 0.877 – 1.14 0.995 232 2320 all phecode
753 Congenital anomalies of the eye Congenital Anomalies 0.898 0.775 – 1.04 0.156 207 2051 all phecode
753.1 Congenital cataract and lens anomalies Congenital Anomalies 0.893 0.679 – 1.17 0.415 58 580 all phecode
753.2 Congenital anomalies of posterior segment of eye Congenital Anomalies 1.02 0.785 – 1.33 0.882 56 546 all phecode
754 Congenital musculoskeletal deformities of spine Congenital Anomalies 0.944 0.889 – 1 0.0612 1216 12116 all phecode
754.1 Lumbosacral spondylolysis, congenital Congenital Anomalies 0.945 0.791 – 1.13 0.534 135 1333 all phecode
754.2 Spondylolisthesis, congenital Congenital Anomalies 0.937 0.857 – 1.02 0.152 558 5570 all phecode
755 Congenital anomalies of limbs Congenital Anomalies 0.929 0.861 – 1 0.0572 747 7458 all phecode
755.1 Congenital deformities of feet Congenital Anomalies 0.962 0.864 – 1.07 0.476 368 3663 all phecode
755.4
Congenital anomalies of upper limb, including
Congenital anomalies of upper limb, including shoulder girdle
 Congenital Anomalies 0.837 0.65 – 1.08 0.17 74 740 all phecode
755.6
Other congenital anomalies of lower limb
Other congenital anomalies of lower limb, including pelvic girdle
 Congenital Anomalies 0.873 0.776 – 0.983 0.0246 321 3205 all phecode
755.61 Congenital hip dysplasia and deformity Congenital Anomalies 0.865 0.741 – 1.01 0.0652 185 1847 all phecode
756 Other congenital musculoskeletal anomalies Congenital Anomalies 0.969 0.915 – 1.03 0.273 1358 13579 all phecode
756.1 Congenital anomalies of abdominal wall; diaphram Congenital Anomalies 1.07 0.835 – 1.37 0.6 68 680 all phecode
756.2
Pectus and other congenital anomalies of
Pectus and other congenital anomalies of ribs/sternum
 Congenital Anomalies 1.18 0.934 – 1.49 0.167 71 694 all phecode
756.3
Congenital anomalies of muscle, tendon, fascia
Congenital anomalies of muscle, tendon, fascia, and connective tissue
 Congenital Anomalies 1 0.898 – 1.12 0.95 335 3346 all phecode
756.5 Congenital osteodystrophies Congenital Anomalies 0.958 0.897 – 1.02 0.203 1003 10014 all phecode
757 Congenital anomalies of the integument Congenital Anomalies 1.02 0.921 – 1.13 0.715 401 4001 all phecode
758 Chromosomal anomalies and genetic disorders Congenital Anomalies 0.89 0.762 – 1.04 0.142 185 1845 all phecode
758.1 Chromosomal anomalies Congenital Anomalies 0.938 0.786 – 1.12 0.477 135 1349 all phecode
759 Other and unspecified congenital anomalies Congenital Anomalies 0.933 0.852 – 1.02 0.13 557 5566 all phecode
759.1 Anomalies of endocrine glands, congenital Congenital Anomalies 0.796 0.609 – 1.04 0.0948 71 710 all phecode
760 Back pain Symptoms 0.993 0.974 – 1.01 0.458 16037 30719 all phecode
761 Cervicalgia Symptoms 1.02 0.992 – 1.05 0.175 6528 39755 all phecode
763
Thoracic or lumbosacral neuritis or
Thoracic or lumbosacral neuritis or radiculitis, unspecified
 Symptoms 0.984 0.95 – 1.02 0.349 3657 32599 all phecode
764 Sciatica Symptoms 1.01 0.979 – 1.05 0.467 3542 32015 all phecode
765 Cervical radiculitis Symptoms 0.952 0.906 – 1 0.0539 1799 17851 all phecode
766 Neuralgia, neuritis, and radiculitis NOS Symptoms 0.983 0.954 – 1.01 0.245 5124 37132 all phecode
767 Cervicocranial/Cervicobrachial syndrome Symptoms 1.08 0.898 – 1.29 0.427 117 1168 all phecode
769 Nonallopathic lesions NEC Symptoms 0.954 0.896 – 1.02 0.142 1131 11220 all phecode
770 Myalgia and myositis unspecified Symptoms 0.992 0.964 – 1.02 0.599 5533 34303 all phecode
771 Musculoskeletal symptoms referable to limbs Symptoms 0.998 0.968 – 1.03 0.883 4799 35575 all phecode
771.1 Swelling of limb Symptoms 1 0.972 – 1.03 0.999 5743 35539 all phecode
771.2 Cramp of limb Symptoms 1.02 0.958 – 1.08 0.541 1079 10568 all phecode
772 Symptoms of the muscles Symptoms 1.01 0.968 – 1.06 0.604 2042 20221 all phecode
772.1 Muscular wasting and disuse atrophy Symptoms 1.03 0.936 – 1.14 0.517 422 4199 all phecode
772.2 Spasm of muscle Symptoms 0.986 0.944 – 1.03 0.523 2299 22726 all phecode
772.3 Muscle weakness Symptoms 1.02 0.985 – 1.06 0.238 2949 28064 all phecode
772.4 Rhabdomyolysis Symptoms 0.965 0.822 – 1.13 0.664 159 1572 all phecode
772.6 Facial weakness Symptoms 1.01 0.918 – 1.11 0.865 478 4742 all phecode
780 Hypothermia/Chills Symptoms 1.01 0.915 – 1.11 0.873 453 4514 all phecode
781
Symptoms involving nervous and musculoskeletal
Symptoms involving nervous and musculoskeletal systems
 Symptoms 1.01 0.967 – 1.05 0.775 2822 26225 all phecode
781.1 Loss of height Symptoms 0.983 0.824 – 1.17 0.85 130 1269 all phecode
781.2 Abnormal posture Symptoms 1.05 0.822 – 1.34 0.703 57 567 all phecode
782.3 Edema Symptoms 1 0.974 – 1.03 0.935 5874 36788 all phecode
782.6 Pallor and flushing Symptoms 1 0.939 – 1.07 0.89 927 9252 all phecode
783 Fever of unknown origin Symptoms 1 0.976 – 1.03 0.817 5733 40720 all phecode
783.1 Postprocedural fever Symptoms 1.05 0.932 – 1.17 0.449 300 2992 all phecode
785 Abdominal pain Symptoms 0.984 0.965 – 1 0.106 16458 30297 all phecode
788 Syncope and collapse Symptoms 1.04 1.01 – 1.08 0.0121 3851 35832 all phecode
789 Nausea and vomiting Symptoms 0.996 0.974 – 1.02 0.69 10568 36098 all phecode
789.1 Persistent vomiting Symptoms 0.924 0.856 – 0.996 0.0389 798 7924 all phecode
790 Nonspecific findings on examination of blood Symptoms 0.991 0.95 – 1.03 0.684 2363 22690 all phecode
790.1 Elevated sedimentation rate Symptoms 1.05 0.925 – 1.19 0.449 236 2322 all phecode
790.6 Other abnormal blood chemistry Symptoms 0.998 0.974 – 1.02 0.896 7539 37788 all phecode
790.8 Elevated C-reactive protein (CRP) Symptoms 1.07 0.958 – 1.2 0.224 309 3075 all phecode
790.9 Abnormal arterial blood gases Symptoms 0.998 0.844 – 1.18 0.981 155 1521 all phecode
791 Gangrene Symptoms 1.07 0.958 – 1.19 0.231 313 3115 all phecode
792
Abnormal Papanicolaou smear of cervix and
Abnormal Papanicolaou smear of cervix and cervical HPV
 Genitourinary 1.01 0.966 – 1.05 0.784 2820 14872 all phecode
792.1
Papanicolaou smear of cervix or vagina with
Papanicolaou smear of cervix or vagina with atypical squamous cells
 Genitourinary 0.982 0.922 – 1.05 0.571 1100 9861 all phecode
794
Abnormal results of other function studies
Abnormal results of other function studies (bladder, pancreas, placenta, spleen, etc)
 Symptoms 1.06 0.973 – 1.16 0.175 515 5133 all phecode
795
Other and nonspecific abnormal cytological
Other and nonspecific abnormal cytological, histological and immunological findings
 Symptoms 1.01 0.965 – 1.05 0.717 2182 20242 all phecode
795.8 Abnormal tumor markers Symptoms 1.02 0.973 – 1.07 0.38 1745 15551 all phecode
795.81 Elevated carcinoembryonic antigen [CEA] Symptoms 0.949 0.739 – 1.22 0.683 61 605 all phecode
795.82 Elevated cancer antigen 125 [CA 125] Symptoms 0.989 0.855 – 1.14 0.882 201 2000 all phecode
796 Elevated prostate specific antigen [PSA] Genitourinary 1.01 0.962 – 1.06 0.724 2125 9930 all phecode
797 Shock Symptoms 1.06 0.979 – 1.15 0.145 605 6050 all phecode
797.1 Cardiogenic shock Symptoms 1.17 1.03 – 1.32 0.0131 242 2420 all phecode
798 Malaise and fatigue Symptoms 1.01 0.984 – 1.03 0.629 11539 35196 all phecode
798.1 Chronic fatigue syndrome Symptoms 0.983 0.937 – 1.03 0.498 1823 17795 all phecode
800 Fracture of lower limb Injuries & Poisonings 1 0.959 – 1.04 0.99 2344 22951 all phecode
800.1 Fracture of neck of femur Injuries & Poisonings 1.06 0.97 – 1.16 0.202 512 4961 all phecode
800.2 Fracture of unspecified part of femur Injuries & Poisonings 1.03 0.956 – 1.12 0.399 670 6582 all phecode
800.3 Fracture of tibia and fibula Injuries & Poisonings 1 0.937 – 1.07 0.938 898 8966 all phecode
800.4 Fracture of patella Injuries & Poisonings 1.01 0.912 – 1.13 0.792 346 3456 all phecode
801 Fracture of ankle and foot Injuries & Poisonings 0.964 0.923 – 1.01 0.0922 2358 22645 all phecode
801.1 Fracture of foot Injuries & Poisonings 0.957 0.899 – 1.02 0.172 1120 11178 all phecode
802 Fracture of pelvis Injuries & Poisonings 0.917 0.821 – 1.02 0.125 380 3765 all phecode
803 Fracture of upper limb Injuries & Poisonings 1.01 0.965 – 1.06 0.679 2051 20360 all phecode
803.1 Fracture of humerus Injuries & Poisonings 1.08 1 – 1.16 0.0468 734 7322 all phecode
803.2 Fracture of radius and ulna Injuries & Poisonings 1.02 0.956 – 1.08 0.619 1112 11075 all phecode
803.21 Colles' fracture Injuries & Poisonings 1.01 0.901 – 1.14 0.826 291 2904 all phecode
803.3 Fracture of clavicle or scapula Injuries & Poisonings 1.02 0.933 – 1.12 0.653 514 5140 all phecode
804 Fracture of hand or wrist Injuries & Poisonings 0.997 0.948 – 1.05 0.916 1628 16042 all phecode
805
Fracture of vertebral column without mention of
Fracture of vertebral column without mention of spinal cord injury
 Injuries & Poisonings 1 0.948 – 1.06 0.912 1336 13242 all phecode
807 Fracture of ribs Injuries & Poisonings 1.01 0.935 – 1.09 0.791 683 6815 all phecode
809 Fracture of unspecified bones Injuries & Poisonings 0.976 0.939 – 1.01 0.209 2941 28633 all phecode
816 Cerebral laceration and contusion Injuries & Poisonings 0.833 0.609 – 1.14 0.251 54 531 all phecode
817 Concussion Injuries & Poisonings 0.982 0.92 – 1.05 0.585 1018 10149 all phecode
818 Intracranial hemorrhage (injury) Injuries & Poisonings 1.03 0.925 – 1.16 0.548 311 3104 all phecode
818.1 Subdural hemorrhage (injury) Injuries & Poisonings 0.936 0.753 – 1.16 0.552 90 895 all phecode
818.2 Subarachnoid hemorrhage (injury) Injuries & Poisonings 1.03 0.841 – 1.26 0.773 97 970 all phecode
819
Skull and face fracture and other intercranial
Skull and face fracture and other intercranial injury
 Injuries & Poisonings 1.01 0.972 – 1.06 0.519 2287 22671 all phecode
830 Dislocation Injuries & Poisonings 1.01 0.98 – 1.05 0.443 3862 34720 all phecode
835 Internal derangement of knee Injuries & Poisonings 1 0.959 – 1.05 0.921 2231 21628 all phecode
836 Traumatic arthropathy Injuries & Poisonings 0.899 0.816 – 0.99 0.0312 496 4954 all phecode
840 Sprains and strains Injuries & Poisonings 1 0.978 – 1.03 0.885 7838 37998 all phecode
840.1 Muscle/tendon sprain Injuries & Poisonings 0.955 0.873 – 1.05 0.325 537 5356 all phecode
840.2 Rotator cuff (capsule) sprain Injuries & Poisonings 1.03 0.98 – 1.08 0.243 1640 16263 all phecode
840.3 Joint/ligament sprain Injuries & Poisonings 1.01 0.976 – 1.05 0.477 2875 24879 all phecode
841 Sprains and strains of back and neck Injuries & Poisonings 1 0.951 – 1.05 0.974 1583 15592 all phecode
842 Other sprains and strains Injuries & Poisonings 1 0.947 – 1.06 0.99 1407 13924 all phecode
850 Hemorrhage or hematoma complicating a procedure Injuries & Poisonings 0.991 0.948 – 1.04 0.709 2072 20649 all phecode
851
Complications of transplants and reattached
Complications of transplants and reattached limbs
 Injuries & Poisonings 0.989 0.952 – 1.03 0.567 2982 27545 all phecode
853 Complication of colostomy or enterostomy Injuries & Poisonings 0.995 0.904 – 1.1 0.923 460 4600 all phecode
854
Complications of cardiac/vascular device
Complications of cardiac/vascular device, implant, and graft
 Injuries & Poisonings 0.981 0.937 – 1.03 0.427 1985 19675 all phecode
855
Complication of nervous system device, implant
Complication of nervous system device, implant, and graft
 Injuries & Poisonings 1.05 0.924 – 1.18 0.478 264 2640 all phecode
856
Vascular complications of surgery and medical
Vascular complications of surgery and medical procedures
 Injuries & Poisonings 1.03 0.918 – 1.16 0.597 293 2929 all phecode
857
Mechanical complication of unspecified
Mechanical complication of unspecified genitourinary device, implant, and graft
 Injuries & Poisonings 0.989 0.935 – 1.05 0.71 1310 13087 all phecode
858 Complication of internal orthopedic device Injuries & Poisonings 0.99 0.947 – 1.03 0.647 2213 21944 all phecode
859
Complication due to other implant and internal
Complication due to other implant and internal device
 Injuries & Poisonings 0.978 0.935 – 1.02 0.336 2110 21070 all phecode
860 Bone marrow or stem cell transplant Neoplasms 1 0.859 – 1.18 0.95 166 1660 all phecode
870 Open wounds of head; neck; and trunk Injuries & Poisonings 1.01 0.975 – 1.04 0.657 4117 36734 all phecode
870.1 Open wound or laceration of eye or eyelid Injuries & Poisonings 0.875 0.747 – 1.02 0.0964 204 2026 all phecode
870.2 Open wound of ear Injuries & Poisonings 1.05 0.889 – 1.25 0.545 144 1437 all phecode
870.3 Other open wound of head and face Injuries & Poisonings 1.01 0.958 – 1.07 0.665 1346 13301 all phecode
870.4 Open wound of nose and sinus Injuries & Poisonings 0.917 0.795 – 1.06 0.229 207 2057 all phecode
870.5 Open wound of lip and mouth Injuries & Poisonings 1.04 0.918 – 1.17 0.564 275 2724 all phecode
870.6 Open wound of neck Injuries & Poisonings 1.08 0.947 – 1.23 0.249 214 2128 all phecode
870.8 Open wound of genital organs Injuries & Poisonings 1 0.85 – 1.19 0.959 144 1440 all phecode
871 Open wounds of extremities Injuries & Poisonings 1.01 0.976 – 1.05 0.545 3530 32903 all phecode
871.1 Open wound of hand except finger(s) Injuries & Poisonings 1.03 0.944 – 1.12 0.533 572 5701 all phecode
871.2 Open wound of finger(s) Injuries & Poisonings 1.04 0.972 – 1.1 0.282 984 9772 all phecode
871.3 Open wound of foot except toe(s) alone Injuries & Poisonings 1.01 0.918 – 1.11 0.857 490 4843 all phecode
871.4 Open wound of toe(s) Injuries & Poisonings 1.09 0.964 – 1.22 0.174 295 2921 all phecode
872 Traumatic amputation Injuries & Poisonings 1.07 0.986 – 1.17 0.102 551 5477 all phecode
874 Complication of amputation stump Injuries & Poisonings 1.02 0.879 – 1.19 0.783 170 1697 all phecode
875 Non-healing surgical wound Injuries & Poisonings 0.962 0.882 – 1.05 0.383 572 5720 all phecode
876
Posttraumatic wound infection not elsewhere
Posttraumatic wound infection not elsewhere classified
 Injuries & Poisonings 1.02 0.952 – 1.1 0.544 802 8003 all phecode
907 Injuries to the nervous system Injuries & Poisonings 0.994 0.932 – 1.06 0.864 1010 10096 all phecode
910 Superficial injury, infected Injuries & Poisonings 1.02 0.852 – 1.22 0.838 119 1161 all phecode
911 Blister Injuries & Poisonings 0.919 0.814 – 1.04 0.174 302 2996 all phecode
912 Insect bite Injuries & Poisonings 1.01 0.924 – 1.11 0.791 492 4886 all phecode
913 Toxic effect of venom Injuries & Poisonings 0.914 0.814 – 1.03 0.128 337 3326 all phecode
916 Contusion Injuries & Poisonings 1.01 0.978 – 1.04 0.584 4296 38033 all phecode
930 Allergic reaction to food Injuries & Poisonings 1.04 0.966 – 1.12 0.309 763 7596 all phecode
931
Contact dermatitis and other eczema due to
Contact dermatitis and other eczema due to plants [except food]
 Dermatologic 1.01 0.937 – 1.09 0.766 714 7072 all phecode
938 Dermatitis due to solar radiation Dermatologic 0.994 0.965 – 1.02 0.669 5567 29098 all phecode
938.1 Acute dermatitis due to solar radiation Dermatologic 0.936 0.807 – 1.09 0.388 217 2164 all phecode
938.2 Chronic dermatitis due to solar radiation Dermatologic 0.995 0.965 – 1.02 0.724 5307 28656 all phecode
939
Atopic/contact dermatitis due to other or
Atopic/contact dermatitis due to other or unspecified
 Dermatologic 0.979 0.953 – 1.01 0.117 6704 32389 all phecode
939.1 Contact and allergic dermatitis of eyelid Dermatologic 1.21 0.998 – 1.46 0.052 91 870 all phecode
941 Adverse reaction to serum or vaccine Injuries & Poisonings 0.932 0.799 – 1.09 0.372 188 1880 all phecode
942 Infusion and transfusion reaction Injuries & Poisonings 1.01 0.888 – 1.14 0.919 269 2688 all phecode
946 Anaphylactic shock NOS Injuries & Poisonings 0.991 0.905 – 1.08 0.842 500 4940 all phecode
947 Urticaria Dermatologic 0.934 0.878 – 0.994 0.0318 1177 11454 all phecode
949 Allergies, other Injuries & Poisonings 1 0.977 – 1.03 0.827 7251 32350 all phecode
952
Spinal cord injury without evidence of spinal
Spinal cord injury without evidence of spinal bone injury
 Injuries & Poisonings 0.998 0.91 – 1.09 0.962 494 4940 all phecode
957 Injury to other and unspecified nerves Injuries & Poisonings 1.04 0.878 – 1.23 0.645 136 1352 all phecode
958
Certain early complications of trauma or
Certain early complications of trauma or procedure
 Injuries & Poisonings 0.995 0.939 – 1.05 0.869 1217 12158 all phecode
958.1 Postoperative shock Injuries & Poisonings 0.912 0.773 – 1.08 0.277 169 1688 all phecode
958.2 Traumatic and surgical subcutaneous emphysema Injuries & Poisonings 0.923 0.752 – 1.13 0.443 114 1140 all phecode
960 Poisoning by antibiotics Injuries & Poisonings 0.979 0.939 – 1.02 0.317 2479 22087 all phecode
960.1
Adverse effects of antibacterials (not
Adverse effects of antibacterials (not penicillins)
 Injuries & Poisonings 0.919 0.82 – 1.03 0.14 342 3403 all phecode
960.2 Allergy/adverse effect of penicillin Injuries & Poisonings 0.975 0.926 – 1.03 0.341 1636 16005 all phecode
961 Poisoning by other anti-infectives Injuries & Poisonings 1.07 0.978 – 1.16 0.144 528 5234 all phecode
961.1 Poisoning/allergy of sulfonamides Injuries & Poisonings 1.05 0.991 – 1.12 0.0975 1065 10347 all phecode
962 Poisoning by hormones and synthetic substitutes Injuries & Poisonings 1.02 0.953 – 1.1 0.525 803 7976 all phecode
962.1
Adrenal cortical steroids causing adverse
Adrenal cortical steroids causing adverse effects in therapeutic use
 Injuries & Poisonings 1.05 0.951 – 1.17 0.315 379 3782 all phecode
962.2
Insulins and antidiabetic agents causing
Insulins and antidiabetic agents causing adverse effects in therapeutic use
 Injuries & Poisonings 1.1 0.853 – 1.41 0.47 62 612 all phecode
962.3
Hormones and synthetic substitutes causing
Hormones and synthetic substitutes causing adverse effects in therapeutic use
 Injuries & Poisonings 0.968 0.881 – 1.06 0.505 478 4773 all phecode
963 Poisoning by primarily systemic agents Injuries & Poisonings 0.992 0.952 – 1.03 0.686 2533 24531 all phecode
963.1
Antineoplastic and immunosuppressive drugs
Antineoplastic and immunosuppressive drugs causing adverse effects
 Injuries & Poisonings 0.992 0.952 – 1.03 0.719 2469 24057 all phecode
964
Poisoning by agents primarily affecting blood
Poisoning by agents primarily affecting blood constituents
 Injuries & Poisonings 0.985 0.914 – 1.06 0.702 743 7337 all phecode
964.1 Anticoagulants causing adverse effects Injuries & Poisonings 0.991 0.918 – 1.07 0.822 712 7027 all phecode
965
Poisoning by analgesics, antipyretics, and
Poisoning by analgesics, antipyretics, and antirheumatics
 Injuries & Poisonings 1.02 0.951 – 1.09 0.594 864 8601 all phecode
965.1
Opiates and related narcotics causing adverse
Opiates and related narcotics causing adverse effects in therapeutic use
 Injuries & Poisonings 1.01 0.955 – 1.06 0.785 1469 14402 all phecode
965.3
Salicylates causing adverse effects in
Salicylates causing adverse effects in therapeutic use
 Injuries & Poisonings 0.957 0.789 – 1.16 0.657 119 1182 all phecode
966
Poisoning by anticonvulsants and
Poisoning by anticonvulsants and anti-Parkinsonism drugs
 Injuries & Poisonings 1.06 0.887 – 1.27 0.51 103 1006 all phecode
967
Adverse effects of sedatives or other central
Adverse effects of sedatives or other central nervous system depressants and anesthetics
 Injuries & Poisonings 0.962 0.907 – 1.02 0.195 1254 12464 all phecode
969 Poisoning by psychotropic agents Injuries & Poisonings 1 0.886 – 1.13 0.999 281 2797 all phecode
971
Poisoning by drugs primarily affecting the
Poisoning by drugs primarily affecting the autonomic nervous system
 Injuries & Poisonings 0.9 0.698 – 1.16 0.419 67 643 all phecode
972
Poisoning by agents primarily affecting the
Poisoning by agents primarily affecting the cardiovascular system
 Injuries & Poisonings 1.06 0.946 – 1.19 0.315 288 2858 all phecode
972.1
Cardiac rhythm regulators causing adverse
Cardiac rhythm regulators causing adverse effects in therapeutic use
 Injuries & Poisonings 0.988 0.779 – 1.25 0.918 80 776 all phecode
972.6 Antihypertensive agents causing adverse effects Injuries & Poisonings 1.18 0.98 – 1.42 0.0803 104 1034 all phecode
974
Poisoning by water, mineral, and uric acid
Poisoning by water, mineral, and uric acid metabolism drugs
 Injuries & Poisonings 0.919 0.753 – 1.12 0.407 113 1130 all phecode
975
Poisoning by agents primarily acting on the
Poisoning by agents primarily acting on the smooth and skeletal muscles and respiratory system
 Injuries & Poisonings 0.879 0.694 – 1.11 0.285 81 810 all phecode
976
Poisoning by agents primarily affecting skin &
Poisoning by agents primarily affecting skin & mucous membrane, ophthalmological, otorhinolaryngological, & dental drugs
 Injuries & Poisonings 1.04 0.831 – 1.29 0.753 71 703 all phecode
977 Personal history of allergy to medicinal agents Injuries & Poisonings 1.03 0.983 – 1.08 0.215 1763 16599 all phecode
979 Adverse drug events and drug allergies Injuries & Poisonings 0.982 0.948 – 1.02 0.319 3448 30885 all phecode
980
Encounter for long-term (current) use of
Encounter for long-term (current) use of antibiotics
 Infectious Diseases 1.05 0.992 – 1.1 0.0983 1391 13877 all phecode
985 Toxic effect of other metals Injuries & Poisonings 1.13 0.886 – 1.44 0.327 57 564 all phecode
989
Toxic effect of other substances, chiefly
Toxic effect of other substances, chiefly nonmedicinal as to source
 Injuries & Poisonings 0.914 0.763 – 1.09 0.325 129 1275 all phecode
990 Effects radiation NOS Injuries & Poisonings 0.995 0.963 – 1.03 0.785 3927 31223 all phecode
994 Sepsis and SIRS Injuries & Poisonings 1 0.959 – 1.05 0.952 2192 21710 all phecode
994.1 Systemic inflammatory response syndrome (SIRS) Injuries & Poisonings 1.04 0.916 – 1.17 0.577 291 2910 all phecode
994.2 Sepsis Injuries & Poisonings 0.995 0.951 – 1.04 0.832 2086 20666 all phecode
994.21 Septic shock Injuries & Poisonings 1.02 0.946 – 1.11 0.553 627 6260 all phecode
008 Intestinal infection Infectious Diseases 1.1 0.942 – 1.28 0.211 179 806 exclusion phecode
008.5 Bacterial enteritis Infectious Diseases 1.13 0.874 – 1.43 0.314 57 348 exclusion phecode
008.52 Intestinal infection due to C. difficile Infectious Diseases 1.11 0.793 – 1.46 0.509 40 258 exclusion phecode
008.6 Viral Enteritis Infectious Diseases 1.16 0.865 – 1.53 0.31 70 261 exclusion phecode
010 Tuberculosis Infectious Diseases 0.776 0.319 – 1.6 0.531 14 58 exclusion phecode
031 Diseases due to other mycobacteria Infectious Diseases 0.997 0.692 – 1.23 1 2 16 exclusion phecode
038 Septicemia Infectious Diseases 1.13 0.914 – 1.38 0.239 85 492 exclusion phecode
038.1 Gram negative septicemia Infectious Diseases 0.848 0.475 – 1.38 0.537 22 114 exclusion phecode
038.2 Gram positive septicemia Infectious Diseases 0.969 0.483 – 1.61 0.914 6 49 exclusion phecode
038.3 Bacteremia Infectious Diseases 1.14 0.813 – 1.54 0.408 39 227 exclusion phecode
041 Bacterial infection NOS Infectious Diseases 0.925 0.792 – 1.07 0.312 226 998 exclusion phecode
041.1 Staphylococcus infections Infectious Diseases 1.02 0.732 – 1.38 0.878 55 364 exclusion phecode
041.11 Methicillin sensitive Staphylococcus aureus Infectious Diseases 0.743 0.389 – 1.27 0.292 29 192 exclusion phecode
041.12 Methicillin resistant Staphylococcus aureus Infectious Diseases 1.05 0.629 – 1.56 0.838 28 174 exclusion phecode
041.2 Streptococcus infection Infectious Diseases 1.08 0.829 – 1.37 0.531 61 350 exclusion phecode
041.21 Rheumatic fever / chorea Infectious Diseases 0.783 0.192 – 1.33 0.485 7 49 exclusion phecode
041.4 E. coli Infectious Diseases 0.82 0.564 – 1.12 0.248 45 283 exclusion phecode
041.8 H. pylori Infectious Diseases 0.817 0.411 – 1.33 0.469 11 75 exclusion phecode
041.9 Infection with drug-resistant microorganisms Infectious Diseases 1.37 0.773 – 2.71 0.241 12 90 exclusion phecode
053 Herpes zoster Infectious Diseases 0.939 0.729 – 1.18 0.612 89 246 exclusion phecode
053.1 Herpes zoster with nervous system complications Infectious Diseases 0.911 0.374 – 1.91 0.82 7 42 exclusion phecode
054 Herpes simplex Infectious Diseases 0.824 0.637 – 1.04 0.122 109 356 exclusion phecode
070 Viral hepatitis Infectious Diseases 0.626 0.315 – 1.08 0.114 23 112 exclusion phecode
070.1 Viral hepatitis A Infectious Diseases 0.658 0.00546 – 41.8 0.868 4 9 exclusion phecode
070.2 Viral hepatitis B Infectious Diseases 0.891 0.045 – 2 0.811 7 22 exclusion phecode
070.3 Viral hepatitis C Infectious Diseases 0.575 0.228 – 1.24 0.187 12 66 exclusion phecode
070.4 Chronic hepatitis Infectious Diseases 0.886 0.347 – 1.92 0.783 10 30 exclusion phecode
070.9 Hepatitis NOS Infectious Diseases 0.994 0.663 – 1.45 0.976 34 130 exclusion phecode
071 Human immunodeficiency virus [HIV] disease Infectious Diseases 1.4 0.566 – 3.46 0.476 11 25 exclusion phecode
071.1 HIV infection, symptomatic Infectious Diseases 0.991 0.353 – 2.45 0.986 8 19 exclusion phecode
078 Viral warts & HPV Infectious Diseases 0.923 0.787 – 1.07 0.313 235 577 exclusion phecode
079 Viral infection Infectious Diseases 0.967 0.853 – 1.09 0.599 449 612 exclusion phecode
079.1 Varicella infection Infectious Diseases 0.898 0.764 – 1.05 0.186 253 581 exclusion phecode
079.2 Infectious mononucleosis Infectious Diseases 1.23 0.646 – 2.38 0.533 20 58 exclusion phecode
079.9 Viremia, NOS Infectious Diseases 0.989 0.735 – 1.3 0.941 65 177 exclusion phecode
080 Postoperative infection Infectious Diseases 0.98 0.774 – 1.21 0.858 94 692 exclusion phecode
081
Infection/inflammation of internal prosthetic
Infection/inflammation of internal prosthetic device; implant; and graft
 Infectious Diseases 1.24 0.912 – 1.65 0.159 54 331 exclusion phecode
090
Sexually transmitted infections (not HIV or
Sexually transmitted infections (not HIV or hepatitis)
 Infectious Diseases 1.22 0.977 – 1.5 0.073 78 406 exclusion phecode
110 Dermatophytosis / Dermatomycosis Infectious Diseases 1.02 0.871 – 1.19 0.791 206 601 exclusion phecode
110.1 Dermatophytosis Infectious Diseases 0.992 0.838 – 1.16 0.92 186 527 exclusion phecode
110.11 Dermatophytosis of nail Infectious Diseases 1.23 0.994 – 1.52 0.0611 106 293 exclusion phecode
110.12 Althete's foot Infectious Diseases 0.959 0.703 – 1.26 0.783 54 159 exclusion phecode
110.13 Dermatophytosis of the body Infectious Diseases 0.845 0.572 – 1.21 0.383 57 168 exclusion phecode
110.2 Dermatomycoses Infectious Diseases 1.3 0.896 – 1.89 0.177 35 102 exclusion phecode
112 Candidiasis Infectious Diseases 1.01 0.871 – 1.16 0.924 255 756 exclusion phecode
112.3 Candidiasis of skin and nails Infectious Diseases 1.47 1.06 – 2.04 0.0232 39 174 exclusion phecode
117 Mycoses Infectious Diseases 0.999 0.675 – 1.39 0.995 36 126 exclusion phecode
117.1 Histoplasmosis Infectious Diseases 1.76 0.545 – 12.7 0.482 4 15 exclusion phecode
117.4 Aspergillosis Infectious Diseases 1.14 0.367 – 3.8 0.832 8 22 exclusion phecode
130 Spirochetal infection Infectious Diseases 1.3 0.369 – 5.53 0.696 9 39 exclusion phecode
130.1 Lyme disease Infectious Diseases 0.763 0.0842 – 3.13 0.702 7 29 exclusion phecode
131 Protozoan infection Infectious Diseases 0.956 0.434 – 1.75 0.902 9 34 exclusion phecode
132 Infestation (lice, mites) Infectious Diseases 0.831 0.41 – 1.47 0.569 13 52 exclusion phecode
134 Helminthiases Infectious Diseases 0.703 0.062 – 6.25 0.746 3 22 exclusion phecode
134.1 Intestinal helminthiases Infectious Diseases 1.18 0.0266 – 80.7 0.928 2 11 exclusion phecode
136 Other infectious and parasitic diseases Infectious Diseases 0.893 0.75 – 1.05 0.187 182 876 exclusion phecode
145 Cancer of mouth Neoplasms 1.11 0.639 – 1.79 0.675 16 237 exclusion phecode
145.1 Cancer of lip Neoplasms 3.23 0.357 – 30900 0.417 2 15 exclusion phecode
145.2 Cancer of tongue Neoplasms 2.06 0.98 – 5 0.059 6 106 exclusion phecode
145.3 Cancer of major salivary glands Neoplasms 0.391 0.017 – 1.49 0.229 5 68 exclusion phecode
145.4 Cancer of the gums Neoplasms 1.97 0.201 – 66.6 0.436 1 27 exclusion phecode
145.5 Cancer of the mouth floor Neoplasms 1.01 0.214 – 3.57 0.986 1 30 exclusion phecode
149 Cancer of larynx, pharynx, nasal cavities Neoplasms 1.42 0.858 – 2.24 0.133 16 218 exclusion phecode
149.1 Cancer of oropharynx Neoplasms 1.32 0.132 – 24.8 0.75 1 45 exclusion phecode
149.2 Cancer of nasopharynx Neoplasms 1.49 0.709 – 3.56 0.299 7 33 exclusion phecode
149.3 Cancer of hypopharynx Neoplasms – 0 12 exclusion phecode
149.4 Cancer of larynx Neoplasms 0.741 0.000727 – 2.66 0.639 1 68 exclusion phecode
149.5
Hx of malignant neoplasm of oral cavity and
Hx of malignant neoplasm of oral cavity and pharynx
 Neoplasms 1.35 0.612 – 2.77 0.374 7 90 exclusion phecode
149.9 Cancer of of nasal cavities Neoplasms 1.81 0.233 – 213 0.444 2 51 exclusion phecode
150 Cancer of esophagus Neoplasms 2.11 0.629 – 16.8 0.172 2 42 exclusion phecode
151 Cancer of stomach Neoplasms 0.805 0.267 – 1.9 0.62 4 57 exclusion phecode
153 Colorectal cancer Neoplasms 0.751 0.469 – 1.13 0.19 33 208 exclusion phecode
153.2 Colon cancer Neoplasms 0.886 0.545 – 1.34 0.587 24 158 exclusion phecode
153.3
Malignant neoplasm of rectum, rectosigmoid
Malignant neoplasm of rectum, rectosigmoid junction, and anus
 Neoplasms 0.494 0.21 – 0.986 0.0558 16 134 exclusion phecode
155 Cancer of liver and intrahepatic bile duct Neoplasms 0.999 0.0639 – 3.22 0.998 6 70 exclusion phecode
155.1 Malignant neoplasm of liver, primary Neoplasms 0.952 0.0837 – 2.99 0.932 5 53 exclusion phecode
157 Pancreatic cancer Neoplasms 1.64 0.522 – 6.19 0.379 5 71 exclusion phecode
158
Neoplasm of unspecified nature of digestive
Neoplasm of unspecified nature of digestive system
 Neoplasms 0.959 0.704 – 1.27 0.778 56 263 exclusion phecode
159
Malignant neoplasm of other and ill-defined
Malignant neoplasm of other and ill-defined sites within the digestive organs and peritoneum
 Neoplasms 0.746 0.496 – 1.06 0.123 40 267 exclusion phecode
159.2
Malignant neoplasm of small intestine
Malignant neoplasm of small intestine, including duodenum
 Neoplasms 0.961 0.39 – 2.05 0.923 5 32 exclusion phecode
159.3
Malignant neoplasm of gallbladder and
Malignant neoplasm of gallbladder and extrahepatic bile ducts
 Neoplasms 0.491 1.11e-05 – 27.6 0.763 2 13 exclusion phecode
159.4
Malignant neoplasm of retroperitoneum and
Malignant neoplasm of retroperitoneum and peritoneum
 Neoplasms 0.872 0.397 – 1.67 0.7 7 62 exclusion phecode
164 Cancer of intrathoracic organs Neoplasms 0.563 0.0781 – 2.21 0.425 4 36 exclusion phecode
165 Cancer within the respiratory system Neoplasms 1.01 0.538 – 1.7 0.968 14 226 exclusion phecode
165.1 Cancer of bronchus; lung Neoplasms 1.04 0.546 – 1.8 0.882 12 181 exclusion phecode
170 Cancer of bone and connective tissue Neoplasms 0.703 0.426 – 1.08 0.116 32 341 exclusion phecode
170.1 Bone cancer Neoplasms 0.952 0.519 – 1.57 0.854 15 151 exclusion phecode
170.2 Cancer of connective tissue Neoplasms 0.588 0.298 – 1.02 0.0706 22 236 exclusion phecode
172 Skin cancer Neoplasms 0.961 0.78 – 1.17 0.698 134 884 exclusion phecode
172.1 Melanomas of skin, dx or hx Neoplasms 0.938 0.728 – 1.18 0.599 88 712 exclusion phecode
172.11 Melanomas of skin Neoplasms 1.06 0.767 – 1.41 0.674 38 526 exclusion phecode
172.2 Other non-epithelial cancer of skin Neoplasms 0.918 0.729 – 1.14 0.445 118 726 exclusion phecode
172.21 Basal cell carcinoma Neoplasms 0.896 0.662 – 1.17 0.444 71 441 exclusion phecode
172.22 Squamous cell carcinoma Neoplasms 1.06 0.714 – 1.5 0.737 35 242 exclusion phecode
172.3 Carcinoma in situ of skin Neoplasms 0.672 0.366 – 1.13 0.142 28 213 exclusion phecode
173 Neoplasm of uncertain behavior of skin Neoplasms 0.973 0.782 – 1.19 0.799 103 450 exclusion phecode
174 Breast cancer Neoplasms 1.22 1 – 1.47 0.0481 141 466 exclusion phecode
174.1 Breast cancer [female] Neoplasms 1.2 0.985 – 1.46 0.0693 135 459 exclusion phecode
174.11 Malignant neoplasm of female breast Neoplasms 1.22 1 – 1.49 0.0496 132 451 exclusion phecode
174.3 Neoplasm of uncertain behavior of breast Neoplasms 1.61 0.846 – 3.4 0.175 21 50 exclusion phecode
175 Acquired absence of breast Neoplasms 1.31 0.968 – 1.77 0.081 63 202 exclusion phecode
180 Cervical cancer and dysplasia Neoplasms 1.02 0.812 – 1.28 0.839 104 319 exclusion phecode
180.1 Cervical cancer Neoplasms 1.13 0.577 – 2.17 0.715 14 103 exclusion phecode
180.3
Cervical intraepithelial neoplasia [CIN]
Cervical intraepithelial neoplasia [CIN] [Cervical dysplasia]
 Neoplasms 1.06 0.836 – 1.35 0.612 97 281 exclusion phecode
182 Malignant neoplasm of uterus Neoplasms 1.37 0.722 – 2.52 0.316 18 113 exclusion phecode
184 Cancer of other female genital organs Neoplasms 1.25 0.952 – 1.62 0.104 60 324 exclusion phecode
184.1
Malignant neoplasm of ovary and other uterine
Malignant neoplasm of ovary and other uterine adnexa
 Neoplasms 1.05 0.611 – 1.66 0.85 23 152 exclusion phecode
184.11 Malignant neoplasm of ovary Neoplasms 0.452 0.181 – 0.952 0.0484 18 128 exclusion phecode
184.2
Cancer of other female genital organs
Cancer of other female genital organs (excluding uterus and ovary)
 Neoplasms 1.53 1.12 – 2.11 0.00997 40 165 exclusion phecode
185 Cancer of prostate Neoplasms 1.02 0.575 – 1.67 0.931 22 68 exclusion phecode
187 Cancer of other male genital organs Neoplasms 1.4 0.664 – 3.05 0.385 9 32 exclusion phecode
187.1
Malignant neoplasm of unspecified male genital
Malignant neoplasm of unspecified male genital organ
 Neoplasms 6.79 4.37 – 9.62 0.795 2 8 exclusion phecode
187.2 Malignant neoplasm of testis Neoplasms 7.22 1.53 – 307 0.0573 7 16 exclusion phecode
187.8
Neoplasm of uncertain behavior of male genital
Neoplasm of uncertain behavior of male genital organs
 Neoplasms 0.641 0.0161 – 12.9 0.997 1 5 exclusion phecode
189
Cancer of urinary organs (incl. kidney and
Cancer of urinary organs (incl. kidney and bladder)
 Neoplasms 0.7 0.439 – 1.04 0.0874 37 387 exclusion phecode
189.1 Cancer of kidney and renal pelvis Neoplasms 0.663 0.35 – 1.09 0.124 23 236 exclusion phecode
189.11 Malignant neoplasm of kidney, except pelvis Neoplasms 0.74 0.379 – 1.22 0.264 19 215 exclusion phecode
189.12 Malignant neoplasm of renal pelvis Neoplasms 1.96 0.262 – 10.4 0.384 4 27 exclusion phecode
189.2 Cancer of bladder Neoplasms 0.739 0.37 – 1.26 0.293 18 212 exclusion phecode
189.21 Malignant neoplasm of bladder Neoplasms 0.786 0.365 – 1.39 0.428 13 186 exclusion phecode
189.4 Malignant neoplasm of other urinary organs Neoplasms 0.751 0.239 – 1.73 0.513 7 82 exclusion phecode
190 Cancer of eye Neoplasms 1.3 0.0675 – 9.22 0.78 2 13 exclusion phecode
191
Manlignant and unknown neoplasms of brain and
Manlignant and unknown neoplasms of brain and nervous system
 Neoplasms 1.07 0.618 – 1.73 0.796 18 256 exclusion phecode
191.1 Cancer of brain and nervous system Neoplasms 1.13 0.551 – 2.15 0.717 12 156 exclusion phecode
191.11 Cancer of brain Neoplasms 0.847 0.338 – 1.86 0.678 9 131 exclusion phecode
193 Thyroid cancer Neoplasms 1.34 0.931 – 1.91 0.1 31 310 exclusion phecode
194 Cancer of other endocrine glands Neoplasms 1.46 0.968 – 2.21 0.0671 24 157 exclusion phecode
195 Cancer, suspected or other Neoplasms 1.12 0.98 – 1.29 0.0939 362 752 exclusion phecode
195.1 Malignant neoplasm, other Neoplasms 1.13 0.986 – 1.3 0.0776 358 753 exclusion phecode
195.3 Malignant neoplasm of head, face, and neck Neoplasms 0.922 0.4 – 1.72 0.807 10 130 exclusion phecode
196 Radiotherapy Neoplasms 1.09 0.851 – 1.39 0.473 89 355 exclusion phecode
197 Chemotherapy Neoplasms 1.04 0.859 – 1.26 0.662 144 652 exclusion phecode
198 Secondary malignant neoplasm Neoplasms 0.952 0.758 – 1.18 0.663 113 650 exclusion phecode
198.1 Secondary malignancy of lymph nodes Neoplasms 0.962 0.734 – 1.24 0.771 74 575 exclusion phecode
198.2 Secondary malignancy of respiratory organs Neoplasms 0.793 0.413 – 1.35 0.417 21 177 exclusion phecode
198.3
Secondary malignant neoplasm of digestive
Secondary malignant neoplasm of digestive systems
 Neoplasms 0.915 0.495 – 1.48 0.732 13 157 exclusion phecode
198.4 Secondary malignant neoplasm of liver Neoplasms 0.941 0.538 – 1.51 0.813 18 121 exclusion phecode
198.5 Secondary malignancy of brain/spine Neoplasms 1.12 0.548 – 2.06 0.712 13 110 exclusion phecode
198.6 Secondary malignancy of bone Neoplasms 0.875 0.475 – 1.46 0.623 21 131 exclusion phecode
198.7 Secondary malignant neoplasm of skin Neoplasms 1.13 0.606 – 2.05 0.695 13 52 exclusion phecode
199 Neoplasm of uncertain behavior Neoplasms 1.06 0.911 – 1.23 0.438 228 736 exclusion phecode
199.4 Neurofibromatosis Neoplasms 1.32 0.35 – 7.52 0.686 2 26 exclusion phecode
200 Myeloproliferative disease Neoplasms 0.994 0.675 – 1.41 0.975 39 239 exclusion phecode
200.1 Polycythemia vera Neoplasms 0.872 0.261 – 2.48 0.812 8 35 exclusion phecode
201 Hodgkin's disease Neoplasms 0.952 0.322 – 2.07 0.912 5 38 exclusion phecode
202 Cancer of other lymphoid, histiocytic tissue Neoplasms 1.2 0.875 – 1.62 0.238 50 327 exclusion phecode
202.2 Non-Hodgkins lymphoma Neoplasms 1.29 0.928 – 1.77 0.118 45 280 exclusion phecode
202.21 Nodular lymphoma Neoplasms 1.14 0.766 – 1.65 0.508 34 162 exclusion phecode
202.22 Reticulosarcoma Neoplasms – 0 27 exclusion phecode
202.24 Large cell lymphoma Neoplasms – 0 22 exclusion phecode
204 Leukemia Neoplasms 0.893 0.554 – 1.36 0.616 25 130 exclusion phecode
204.1 Lymphoid leukemia Neoplasms 2.34 0.904 – 8.87 0.1 7 33 exclusion phecode
204.11 Lymphoid leukemia, acute Neoplasms 3.19 1.18 – 26.8 0.0639 7 18 exclusion phecode
204.12 Lymphoid leukemia, chronic Neoplasms 1.29 0.0946 – 8.03 0.712 1 19 exclusion phecode
204.2 Myeloid leukemia Neoplasms 0.864 0.412 – 1.64 0.674 12 62 exclusion phecode
204.21 Myeloid leukemia, acute Neoplasms 0.778 0.185 – 2.5 0.643 6 39 exclusion phecode
204.22 Myeloid leukemia, chronic Neoplasms 0.748 0.117 – 4.01 0.761 3 14 exclusion phecode
204.4 Multiple myeloma Neoplasms 0.824 0.289 – 1.7 0.64 8 35 exclusion phecode
208 Benign neoplasm of colon Neoplasms 0.928 0.812 – 1.06 0.269 397 838 exclusion phecode
209 Neuroendocrine tumors Neoplasms 0.683 0.223 – 1.63 0.402 6 52 exclusion phecode
210 Benign neoplasm of lip, oral cavity, and pharynx Neoplasms 1.03 0.736 – 1.39 0.856 44 459 exclusion phecode
211
Benign neoplasm of other parts of digestive
Benign neoplasm of other parts of digestive system
 Neoplasms 0.964 0.848 – 1.09 0.568 364 861 exclusion phecode
212
Benign neoplasm of respiratory and
Benign neoplasm of respiratory and intrathoracic organs
 Neoplasms 0.915 0.606 – 1.32 0.643 39 396 exclusion phecode
213 Benign neoplasm of bone and articular cartilage Neoplasms 1.12 0.775 – 1.6 0.53 42 171 exclusion phecode
214 Lipoma Neoplasms 1.26 1.02 – 1.55 0.0321 81 340 exclusion phecode
214.1 Lipoma of skin and subcutaneous tissue Neoplasms 1.26 0.962 – 1.63 0.0906 46 216 exclusion phecode
215
Other benign neoplasm of connective and other
Other benign neoplasm of connective and other soft tissue
 Neoplasms 0.982 0.827 – 1.16 0.829 183 983 exclusion phecode
216 Benign neoplasm of skin Neoplasms 0.996 0.888 – 1.12 0.95 593 664 exclusion phecode
216.1 Screening for malignant neoplasms of the skin Neoplasms 1.38 0.844 – 2.39 0.256 20 35 exclusion phecode
217 Vascular hamartomas and non-neoplastic nevi Neoplasms 1.04 0.797 – 1.34 0.779 88 281 exclusion phecode
217.1 Nevus, non-neoplastic Neoplasms 1.01 0.766 – 1.31 0.951 82 257 exclusion phecode
218 Benign neoplasm of uterus Neoplasms 1.1 0.957 – 1.26 0.188 470 408 exclusion phecode
218.1 Uterine leiomyoma Neoplasms 1.17 0.965 – 1.41 0.113 195 377 exclusion phecode
218.2 Other benign neoplasm of uterus Neoplasms 1.09 0.943 – 1.25 0.256 397 405 exclusion phecode
220 Benign neoplasm of ovary Neoplasms 1.17 0.879 – 1.56 0.282 79 198 exclusion phecode
221 Benign neoplasm of other female genital organs Neoplasms 1.21 0.999 – 1.47 0.0554 152 329 exclusion phecode
222 Benign neoplasm of male genital organs Neoplasms 1.17 0.764 – 1.76 0.458 29 91 exclusion phecode
223
Benign neoplasm of kidney and other urinary
Benign neoplasm of kidney and other urinary organs
 Neoplasms 1.35 0.84 – 2.17 0.214 20 114 exclusion phecode
224 Benign neoplasm of eye Neoplasms 0.354 0.171 – 0.652 0.00173 34 128 exclusion phecode
224.1 Benign neoplasm of eye, uveal Neoplasms 0.375 0.179 – 0.69 0.0031 31 117 exclusion phecode
225
Benign neoplasm of brain and other parts of
Benign neoplasm of brain and other parts of nervous system
 Neoplasms 1.25 0.839 – 1.79 0.242 27 296 exclusion phecode
225.1
Benign neoplasm of brain, cranial nerves
Benign neoplasm of brain, cranial nerves, meninges
 Neoplasms 1.12 0.626 – 1.89 0.662 16 236 exclusion phecode
225.2 Benign neoplasm of spinal cord, meninges Neoplasms 1.63 0.899 – 3.16 0.132 11 78 exclusion phecode
226 Benign neoplasm of thyroid glands Neoplasms 1.25 0.941 – 1.62 0.107 45 403 exclusion phecode
227
Benign neoplasm of other endocrine glands and
Benign neoplasm of other endocrine glands and related structures
 Neoplasms 1.21 0.953 – 1.5 0.108 66 432 exclusion phecode
227.1 Benign neoplasm of adrenal gland Neoplasms 1.06 0.709 – 1.49 0.75 22 112 exclusion phecode
227.2 Benign neoplasm of parathyroid gland Neoplasms 1.34 0.914 – 1.85 0.106 19 187 exclusion phecode
227.3
Benign neoplasm of pituitary gland and
Benign neoplasm of pituitary gland and craniopharyngeal duct (pouch)
 Neoplasms 1.1 0.727 – 1.64 0.655 29 128 exclusion phecode
228 Hemangioma and lymphangioma, any site Neoplasms 0.999 0.792 – 1.23 0.991 99 506 exclusion phecode
228.1 Hemangioma of skin and subcutaneous tissue Neoplasms 1.01 0.78 – 1.26 0.955 76 300 exclusion phecode
229 Benign neoplasm of unspecified sites Neoplasms 1.02 0.86 – 1.2 0.813 171 1003 exclusion phecode
229.1 Benign neoplasm of lymph nodes Neoplasms 1.07 0.865 – 1.31 0.504 96 928 exclusion phecode
240 Simple and unspecified goiter Endocrine/metabolic 1.08 0.84 – 1.36 0.546 74 340 exclusion phecode
241 Nontoxic nodular goiter Endocrine/metabolic 1.2 1.01 – 1.43 0.0359 135 676 exclusion phecode
241.1 Nontoxic uninodular goiter Endocrine/metabolic 1.25 1.02 – 1.51 0.0291 111 588 exclusion phecode
241.2 Nontoxic multinodular goiter Endocrine/metabolic 1.48 1.14 – 1.91 0.00299 62 373 exclusion phecode
242 Thyrotoxicosis with or without goiter Endocrine/metabolic 1.03 0.8 – 1.3 0.797 73 400 exclusion phecode
242.1 Graves' disease Endocrine/metabolic 0.858 0.525 – 1.26 0.468 26 172 exclusion phecode
242.2 Toxic multinodular goiter Endocrine/metabolic 1.8 0.964 – 3.77 0.108 12 30 exclusion phecode
242.3 Exophthalmos Endocrine/metabolic 1.25 0.588 – 2.18 0.44 10 78 exclusion phecode
242.31 Thyrotoxic exophthalmos Endocrine/metabolic 0.818 0.109 – 2.13 0.689 6 47 exclusion phecode
244 Hypothyroidism Endocrine/metabolic 0.952 0.828 – 1.09 0.478 309 810 exclusion phecode
244.1 Secondary hypothyroidism Endocrine/metabolic 1.19 0.908 – 1.53 0.19 65 488 exclusion phecode
244.2 Acquired hypothyroidism Endocrine/metabolic 0.915 0.721 – 1.14 0.447 96 357 exclusion phecode
244.4 Hypothyroidism NOS Endocrine/metabolic 0.95 0.824 – 1.09 0.475 293 803 exclusion phecode
245 Thyroiditis Endocrine/metabolic 0.938 0.682 – 1.26 0.682 61 305 exclusion phecode
245.2 Chronic thyroiditis Endocrine/metabolic 0.889 0.624 – 1.23 0.492 50 271 exclusion phecode
245.21 Chronic lymphocytic thyroiditis Endocrine/metabolic 0.878 0.613 – 1.22 0.452 50 266 exclusion phecode
246 Other disorders of thyroid Endocrine/metabolic 1.09 0.938 – 1.26 0.258 218 777 exclusion phecode
246.2 Thyroid cyst Endocrine/metabolic 1.91 0.612 – 11.7 0.309 4 27 exclusion phecode
246.7 Abnormal results of function study of thyroid Endocrine/metabolic 0.892 0.628 – 1.21 0.482 53 246 exclusion phecode
249 Secondary diabetes mellitus Endocrine/metabolic 0.923 0.554 – 1.5 0.753 43 102 exclusion phecode
250 Diabetes mellitus Endocrine/metabolic 0.892 0.781 – 1.02 0.089 501 759 exclusion phecode
250.1 Type 1 diabetes Endocrine/metabolic 0.976 0.736 – 1.28 0.861 115 185 exclusion phecode
250.11 Type 1 diabetes with ketoacidosis Endocrine/metabolic 1.34 0.733 – 2.65 0.394 21 21 exclusion phecode
250.12 Type 1 diabetes with renal manifestations Endocrine/metabolic 1.22 0.642 – 2.51 0.573 25 53 exclusion phecode
250.13 Type 1 diabetes with ophthalmic manifestations Endocrine/metabolic 1.05 0.696 – 1.84 0.843 44 67 exclusion phecode
250.14 Type 1 diabetes with neurological manifestations Endocrine/metabolic 1.29 0.765 – 2.74 0.402 33 54 exclusion phecode
250.15
Diabetes type 1 with peripheral circulatory
Diabetes type 1 with peripheral circulatory disorders
 Endocrine/metabolic 19 0.832 – 1030 0.141 8 12 exclusion phecode
250.2 Type 2 diabetes Endocrine/metabolic 0.991 0.844 – 1.16 0.91 297 687 exclusion phecode
250.21 Type 2 diabetes with ketoacidosis Endocrine/metabolic 1.07 0.511 – 2.18 0.853 24 30 exclusion phecode
250.22 Type 2 diabetes with renal manifestations Endocrine/metabolic 1.43 1.05 – 1.94 0.0262 61 154 exclusion phecode
250.23 Type 2 diabetes with ophthalmic manifestations Endocrine/metabolic 1.06 0.777 – 1.43 0.713 79 122 exclusion phecode
250.24 Type 2 diabetes with neurological manifestations Endocrine/metabolic 1.07 0.811 – 1.4 0.632 91 211 exclusion phecode
250.25
Diabetes type 2 with peripheral circulatory
Diabetes type 2 with peripheral circulatory disorders
 Endocrine/metabolic 0.616 0.25 – 1.31 0.247 23 50 exclusion phecode
250.3 Insulin pump user Endocrine/metabolic 1.09 0.858 – 1.36 0.48 140 338 exclusion phecode
250.4 Abnormal glucose Endocrine/metabolic 0.858 0.742 – 0.989 0.038 413 730 exclusion phecode
250.41 Impaired fasting glucose Endocrine/metabolic 0.934 0.711 – 1.21 0.614 105 311 exclusion phecode
250.42 Other abnormal glucose Endocrine/metabolic 0.867 0.743 – 1.01 0.0642 361 707 exclusion phecode
250.5 Glycosuria or Acetonuria Endocrine/metabolic 1.71 0.288 – 9.37 0.497 6 36 exclusion phecode
250.6 Polyneuropathy in diabetes Endocrine/metabolic 1.04 0.757 – 1.42 0.811 79 166 exclusion phecode
250.7 Diabetic retinopathy Endocrine/metabolic 0.981 0.768 – 1.23 0.874 81 174 exclusion phecode
251 Other disorders of pancreatic internal secretion Endocrine/metabolic 1.1 0.814 – 1.47 0.539 52 159 exclusion phecode
251.1 Hypoglycemia Endocrine/metabolic 0.994 0.697 – 1.39 0.972 66 154 exclusion phecode
252 Disorders of parathyroid gland Endocrine/metabolic 1.09 0.875 – 1.35 0.421 83 371 exclusion phecode
252.1 Hyperparathyroidism Endocrine/metabolic 1.07 0.851 – 1.33 0.537 75 333 exclusion phecode
252.2 Hypoparathyroidism Endocrine/metabolic 0.867 0.522 – 1.29 0.54 17 85 exclusion phecode
253
Disorders of the pituitary gland and its
Disorders of the pituitary gland and its hypothalamic control
 Endocrine/metabolic 0.887 0.667 – 1.16 0.407 84 146 exclusion phecode
253.1 Pituitary hyperfunction Endocrine/metabolic 0.889 0.559 – 1.33 0.61 30 51 exclusion phecode
253.11 Acromegaly and gigantism Endocrine/metabolic 0.355 0.0697 – 1.05 0.186 3 11 exclusion phecode
253.2 Pituitary hypofunction Endocrine/metabolic 1.54 0.818 – 2.97 0.216 21 43 exclusion phecode
253.3 Diabetes insipidus Endocrine/metabolic 1.02 0.301 – 3.32 0.969 7 17 exclusion phecode
253.4 Anterior pituitary disorders Endocrine/metabolic 0.828 0.518 – 1.25 0.44 22 14 exclusion phecode
253.7 Other disorders of neurohypophysis Endocrine/metabolic 1.14 0.0977 – 6.36 0.938 2 8 exclusion phecode
255 Disorders of adrenal glands Endocrine/metabolic 1.03 0.819 – 1.28 0.784 98 260 exclusion phecode
255.1 Adrenal hyperfunction Endocrine/metabolic 1.09 0.775 – 1.52 0.636 40 80 exclusion phecode
255.11 Cushing's syndrome Endocrine/metabolic 1.63 0.91 – 3.12 0.1 27 52 exclusion phecode
255.12 Hyperaldosteronism Endocrine/metabolic 0.812 0.0696 – 2.61 0.718 3 25 exclusion phecode
255.2 Adrenal hypofunction Endocrine/metabolic 0.864 0.626 – 1.15 0.357 57 126 exclusion phecode
255.21 Glucocorticoid deficiency Endocrine/metabolic 0.884 0.635 – 1.19 0.448 55 103 exclusion phecode
256 Ovarian dysfunction Endocrine/metabolic 0.92 0.787 – 1.07 0.291 269 410 exclusion phecode
256.4 Polycystic ovaries Endocrine/metabolic 0.907 0.745 – 1.09 0.323 166 324 exclusion phecode
257 Testicular dysfunction Endocrine/metabolic 1 0.716 – 1.5 0.986 137 36 exclusion phecode
257.1 Testicular hypofunction Endocrine/metabolic 0.973 0.694 – 1.46 0.883 135 36 exclusion phecode
258 Iatrogenic endocrine disorders Endocrine/metabolic 1.14 0.369 – 5.28 0.798 4 14 exclusion phecode
258.1 Postablative ovarian failure Endocrine/metabolic 1.52 0.715 – 3.23 0.273 15 47 exclusion phecode
259 Other endocrine disorders Endocrine/metabolic 0.819 0.641 – 1.03 0.0987 124 201 exclusion phecode
260 Protein-calorie malnutrition Endocrine/metabolic 1.08 0.826 – 1.38 0.553 66 426 exclusion phecode
260.1 Cachexia Endocrine/metabolic 2.31 0.828 – 233 0.157 6 35 exclusion phecode
260.2 severe protein-calorie malnutrition Endocrine/metabolic 1.35 0.929 – 1.9 0.1 25 258 exclusion phecode
260.22 Nutritional marasmus Endocrine/metabolic 1.35 0.8 – 2.29 0.248 9 98 exclusion phecode
260.3 Adult failure to thrive Endocrine/metabolic 1.35 0.781 – 2.38 0.258 10 93 exclusion phecode
260.6 Anorexia Endocrine/metabolic 1.01 0.69 – 1.4 0.961 35 141 exclusion phecode
260.7 Polyphagia Endocrine/metabolic 0.472 0.422 – 1.6 0.357 6 29 exclusion phecode
261 Vitamin deficiency Endocrine/metabolic 0.968 0.86 – 1.09 0.594 502 675 exclusion phecode
261.1 Vitamin A deficiency Endocrine/metabolic 0.923 0.155 – 1.18 0.923 5 20 exclusion phecode
261.2 Vitamin B-complex deficiencies Endocrine/metabolic 1.34 0.953 – 1.88 0.0947 50 174 exclusion phecode
261.4 Vitamin D deficiency Endocrine/metabolic 0.972 0.863 – 1.09 0.635 487 674 exclusion phecode
261.41 Rickets or osteomalacia Endocrine/metabolic 0.205 0.0114 – 1.63 0.27 5 11 exclusion phecode
262 Mineral deficiency NEC Endocrine/metabolic 0.84 0.632 – 1.09 0.204 87 295 exclusion phecode
263 Other nutritional deficiency Endocrine/metabolic 0.959 0.754 – 1.2 0.726 92 333 exclusion phecode
264 Lack of normal physiological development Endocrine/metabolic 0.386 0.071 – 1.15 0.113 9 40 exclusion phecode
264.2 Failure to thrive (childhood) Endocrine/metabolic 2.62 0.54 – 36.7 0.237 3 31 exclusion phecode
264.9
Lack of normal physiological development
Lack of normal physiological development, unspecified
 Endocrine/metabolic 0.918 0.112 – 7.48 0.941 6 14 exclusion phecode
269 Proteinuria Endocrine/metabolic 1.07 0.861 – 1.31 0.526 81 344 exclusion phecode
270
Disorders of protein plasma/amino-acid
Disorders of protein plasma/amino-acid transport and metabolism
 Endocrine/metabolic 1.26 0.934 – 1.68 0.123 35 213 exclusion phecode
270.1 Disturbances of amino-acid transport Endocrine/metabolic 1.66 0.806 – 3.52 0.161 8 61 exclusion phecode
270.11
Disturbances of sulphur-bearing amino-acid
Disturbances of sulphur-bearing amino-acid metabolism
 Endocrine/metabolic 1.87 0.857 – 4.59 0.116 7 55 exclusion phecode
270.2 Disorders of amino-acid metabolism Endocrine/metabolic 1.24 0.581 – 2.85 0.6 6 33 exclusion phecode
270.3 Disorders of plasma protein metabolism Endocrine/metabolic 1.23 0.874 – 1.7 0.23 24 138 exclusion phecode
270.32 Paraproteinemia Endocrine/metabolic 1.12 0.758 – 1.65 0.572 13 58 exclusion phecode
270.33 Amyloidosis Endocrine/metabolic – 0 15 exclusion phecode
270.34 Alpha-1-antitrypsin deficiency Endocrine/metabolic 1.15 0.108 – 10.2 0.883 5 13 exclusion phecode
270.38
Other specified disorders of plasma protein
Other specified disorders of plasma protein metabolism
 Endocrine/metabolic 1.34 0.692 – 2.62 0.388 9 61 exclusion phecode
271
Disorders of carbohydrate transport and
Disorders of carbohydrate transport and metabolism
 Endocrine/metabolic 0.947 0.788 – 1.13 0.552 167 630 exclusion phecode
271.3
Intestinal disaccharidase deficiencies and
Intestinal disaccharidase deficiencies and disaccharide malabsorption
 Endocrine/metabolic 0.946 0.781 – 1.13 0.556 159 605 exclusion phecode
271.9
Other disorders of carbohydrate transport and
Other disorders of carbohydrate transport and metabolism
 Endocrine/metabolic 1.17 0.663 – 2.04 0.621 13 32 exclusion phecode
272 Disorders of lipoid metabolism Endocrine/metabolic 1.06 0.926 – 1.2 0.421 513 741 exclusion phecode
272.1 Hyperlipidemia Endocrine/metabolic 1.06 0.932 – 1.21 0.361 510 741 exclusion phecode
272.11 Hypercholesterolemia Endocrine/metabolic 1.08 0.888 – 1.31 0.444 176 461 exclusion phecode
272.12 Hyperglyceridemia Endocrine/metabolic 1.23 0.89 – 1.69 0.208 64 201 exclusion phecode
272.13 Mixed hyperlipidemia Endocrine/metabolic 1.01 0.802 – 1.26 0.945 147 328 exclusion phecode
272.9 Unspecified disorder of lipoid metabolism Endocrine/metabolic 0.756 0.239 – 2.02 0.589 14 44 exclusion phecode
274 Gout and other crystal arthropathies Endocrine/metabolic 1.28 1 – 1.62 0.0442 60 338 exclusion phecode
274.1 Gout Endocrine/metabolic 1.32 1.03 – 1.68 0.027 58 319 exclusion phecode
274.11 Gouty arthropathy Endocrine/metabolic 1.38 1.02 – 1.86 0.0398 42 156 exclusion phecode
274.2 Crystal arthropathies Endocrine/metabolic 0.931 0.0799 – 3.91 0.907 3 24 exclusion phecode
274.21 Chondrocalcinosis Endocrine/metabolic 0.84 0.0191 – 3.46 0.787 3 18 exclusion phecode
275 Disorders of mineral metabolism Endocrine/metabolic 1.03 0.865 – 1.21 0.74 151 904 exclusion phecode
275.1 Disorders of iron metabolism Hematopoietic 0.524 0.159 – 1.32 0.202 12 48 exclusion phecode
275.11 Hereditary hemochromatosis Hematopoietic 0.627 2.11e-05 – 4.46 0.628 6 19 exclusion phecode
275.2 Disorders of copper metabolism Endocrine/metabolic 1.01 0.116 – 4.38 0.987 2 14 exclusion phecode
275.3 Disorders of magnesium metabolism Endocrine/metabolic 1.29 0.962 – 1.7 0.0848 34 258 exclusion phecode
275.5 Disorders of calcium/phosphorus metabolism Endocrine/metabolic 1.1 0.906 – 1.33 0.309 115 759 exclusion phecode
275.51 Hypocalcemia Endocrine/metabolic 0.967 0.632 – 1.41 0.868 32 263 exclusion phecode
275.53 Disorders of phosphorus metabolism Endocrine/metabolic 1.23 0.867 – 1.69 0.223 39 288 exclusion phecode
275.6 Hypercalcemia Endocrine/metabolic 1.13 0.858 – 1.47 0.359 59 325 exclusion phecode
276
Disorders of fluid, electrolyte, and acid-base
Disorders of fluid, electrolyte, and acid-base balance
 Endocrine/metabolic 0.965 0.846 – 1.1 0.597 319 933 exclusion phecode
276.1 Electrolyte imbalance Endocrine/metabolic 0.908 0.768 – 1.06 0.242 208 828 exclusion phecode
276.11 Hyperosmolality and/or hypernatremia Endocrine/metabolic 1.1 0.578 – 1.95 0.742 11 93 exclusion phecode
276.12 Hyposmolality and/or hyponatremia Endocrine/metabolic 0.855 0.633 – 1.12 0.272 70 383 exclusion phecode
276.13 Hyperpotassemia Endocrine/metabolic 0.999 0.795 – 1.23 0.991 93 461 exclusion phecode
276.14 Hypopotassemia Endocrine/metabolic 0.885 0.69 – 1.11 0.308 99 494 exclusion phecode
276.4 Acid-base balance disorder Endocrine/metabolic 1.05 0.801 – 1.34 0.714 62 406 exclusion phecode
276.41 Acidosis Endocrine/metabolic 1.13 0.855 – 1.45 0.36 53 358 exclusion phecode
276.42 Alkalosis Endocrine/metabolic 0.678 0.272 – 1.41 0.324 15 91 exclusion phecode
276.5 Hypovolemia Endocrine/metabolic 0.992 0.842 – 1.16 0.919 190 841 exclusion phecode
276.6 Fluid overload Endocrine/metabolic 1.11 0.83 – 1.43 0.445 40 216 exclusion phecode
276.8 Polydipsia Endocrine/metabolic 1.14 0.692 – 1.81 0.622 15 36 exclusion phecode
277 Other disorders of metabolism Endocrine/metabolic 0.845 0.718 – 0.987 0.0382 234 892 exclusion phecode
277.2
Other disorders of purine and pyrimidine
Other disorders of purine and pyrimidine metabolism
 Endocrine/metabolic 0.501 0.205 – 1 0.0663 15 81 exclusion phecode
277.4 Disorders of bilirubin excretion Endocrine/metabolic 0.686 0.382 – 1.11 0.154 26 126 exclusion phecode
277.5 Other disorders of lipoid metabolism Endocrine/metabolic 1.03 0.773 – 1.34 0.827 51 239 exclusion phecode
277.51 Lipoprotein disorders Endocrine/metabolic 0.926 0.651 – 1.25 0.643 42 194 exclusion phecode
277.7 Dysmetabolic syndrome X Endocrine/metabolic 1.09 0.848 – 1.38 0.51 95 263 exclusion phecode
278 Overweight, obesity and other hyperalimentation Endocrine/metabolic 0.973 0.869 – 1.09 0.629 716 553 exclusion phecode
278.1 Obesity Endocrine/metabolic 0.976 0.867 – 1.1 0.694 603 553 exclusion phecode
278.11 Morbid obesity Endocrine/metabolic 0.998 0.868 – 1.15 0.972 361 548 exclusion phecode
278.3 Localized adiposity Endocrine/metabolic 0.513 0.206 – 0.96 0.0574 16 102 exclusion phecode
278.4 Abnormal weight gain Endocrine/metabolic 0.99 0.835 – 1.17 0.904 201 480 exclusion phecode
279 Disorders involving the immune mechanism Endocrine/metabolic 0.924 0.749 – 1.13 0.446 130 707 exclusion phecode
279.1 Immunity deficiency Endocrine/metabolic 0.867 0.618 – 1.18 0.38 57 269 exclusion phecode
279.11 Deficiency of humoral immunity Endocrine/metabolic 1.1 0.64 – 1.79 0.705 18 83 exclusion phecode
279.2 Autoimmune disease NEC Endocrine/metabolic 0.83 0.571 – 1.16 0.291 53 254 exclusion phecode
279.7 Other immunological findings Endocrine/metabolic 1.01 0.884 – 1.15 0.857 297 853 exclusion phecode
279.8
Other specified disorders involving the immune
Other specified disorders involving the immune mechanism
 Endocrine/metabolic 0.778 0.507 – 1.14 0.208 43 205 exclusion phecode
280 Iron deficiency anemias Hematopoietic 0.938 0.805 – 1.09 0.402 250 694 exclusion phecode
280.1
Iron deficiency anemias, unspecified or not due
Iron deficiency anemias, unspecified or not due to blood loss
 Hematopoietic 0.938 0.804 – 1.09 0.404 245 693 exclusion phecode
280.2
Iron deficiency anemia secondary to blood loss
Iron deficiency anemia secondary to blood loss (chronic)
 Hematopoietic 0.953 0.742 – 1.2 0.696 88 386 exclusion phecode
281 Other deficiency anemia Hematopoietic 0.855 0.513 – 1.34 0.513 25 115 exclusion phecode
281.1 Megaloblastic anemia Hematopoietic 0.861 0.442 – 1.52 0.634 19 69 exclusion phecode
281.11 Pernicious anemia Hematopoietic 0.63 0.235 – 1.34 0.292 13 33 exclusion phecode
281.12 Other vitamin B12 deficiency anemia Hematopoietic 0.856 0.397 – 1.65 0.669 13 53 exclusion phecode
281.9 Deficiency anemias Hematopoietic 0.922 0.365 – 2 0.838 8 51 exclusion phecode
282 Hereditary hemolytic anemias Hematopoietic 1.35 0.721 – 2.51 0.35 16 53 exclusion phecode
282.8 Other hemoglobinopathies Hematopoietic 1.28 0.646 – 2.57 0.503 13 33 exclusion phecode
282.9 Other hereditary hemolytic anemias Hematopoietic 1.15 0.45 – 2.72 0.776 9 27 exclusion phecode
283 Acquired hemolytic anemias Hematopoietic 0.628 0.0358 – 3.32 0.455 4 38 exclusion phecode
283.1 Autoimmune hemolytic anemias Hematopoietic 0.931 0.055 – 15.5 0.951 2 12 exclusion phecode
284 Aplastic anemia Hematopoietic 0.686 0.39 – 1.13 0.154 27 139 exclusion phecode
284.1 Pancytopenia Hematopoietic 0.709 0.382 – 1.22 0.229 23 121 exclusion phecode
285 Other anemias Hematopoietic 0.926 0.822 – 1.04 0.206 471 733 exclusion phecode
285.1 Acute posthemorrhagic anemia Hematopoietic 0.869 0.684 – 1.08 0.23 102 535 exclusion phecode
285.2 Anemia of chronic disease Hematopoietic 1 0.729 – 1.33 1 56 337 exclusion phecode
285.21 Anemia in chronic kidney disease Hematopoietic 1.13 0.736 – 1.6 0.531 23 145 exclusion phecode
285.22 Anemia in neoplastic disease Hematopoietic 1.01 0.569 – 1.69 0.977 20 116 exclusion phecode
286 Coagulation defects Hematopoietic 1.09 0.913 – 1.28 0.336 143 826 exclusion phecode
286.1 Congenital coagulation defects Hematopoietic 0.949 0.522 – 1.57 0.847 13 74 exclusion phecode
286.11 Von willebrand's disease Hematopoietic 0.217 0.00625 – 0.884 0.0722 4 28 exclusion phecode
286.12
Congenital deficiency of other clotting factors
Congenital deficiency of other clotting factors (including factor VII)
 Hematopoietic 1.07 0.519 – 2.29 0.865 7 35 exclusion phecode
286.2
Encounter for long-term (current) use of
Encounter for long-term (current) use of anticoagulants
 Hematopoietic 0.962 0.742 – 1.21 0.759 90 483 exclusion phecode
286.3
Coagulation defects complicating pregnancy or
Coagulation defects complicating pregnancy or postpartum
 Hematopoietic 1.56 1.08 – 2.31 0.0275 24 79 exclusion phecode
286.4 Acquired coagulation factor deficiency Hematopoietic 0.251 0.00903 – 1.18 0.0899 4 53 exclusion phecode
286.5
Hemorrhagic disorder due to intrinsic
Hemorrhagic disorder due to intrinsic circulating anticoagulants
 Hematopoietic 1.06 0.172 – 5.91 0.943 6 20 exclusion phecode
286.6 Defibrination syndrome Hematopoietic 1.08 0.867 – 1.31 0.488 95 597 exclusion phecode
286.7 Other and unspecified coagulation defects Hematopoietic 1.08 0.892 – 1.29 0.407 118 704 exclusion phecode
286.8 Hypercoagulable state Hematopoietic 1.09 0.828 – 1.39 0.529 53 230 exclusion phecode
286.81 Primary hypercoagulable state Hematopoietic 1.18 0.894 – 1.53 0.232 51 230 exclusion phecode
286.9 Abnormal coagulation profile Hematopoietic 0.875 0.587 – 1.2 0.448 44 204 exclusion phecode
287 Purpura and other hemorrhagic conditions Hematopoietic 0.929 0.727 – 1.17 0.537 101 601 exclusion phecode
287.1 Spontaneous ecchymoses Hematopoietic 0.448 0.0881 – 1.24 0.15 9 67 exclusion phecode
287.3 Thrombocytopenia Hematopoietic 0.955 0.743 – 1.21 0.706 91 537 exclusion phecode
287.31 Primary thrombocytopenia Hematopoietic 1.05 0.616 – 1.72 0.851 17 135 exclusion phecode
287.32 Secondary thrombocytopenia Hematopoietic 1.05 0.576 – 1.75 0.865 18 118 exclusion phecode
287.4 Qualitative platelet defects Hematopoietic 0.828 0.54 – 6.67 0.776 3 28 exclusion phecode
288 Diseases of white blood cells Hematopoietic 0.889 0.746 – 1.05 0.169 187 872 exclusion phecode
288.1 Decreased white blood cell count Hematopoietic 0.807 0.573 – 1.1 0.19 59 331 exclusion phecode
288.11 Neutropenia Hematopoietic 0.899 0.614 – 1.24 0.546 41 227 exclusion phecode
288.2 Elevated white blood cell count Hematopoietic 0.917 0.761 – 1.09 0.341 154 800 exclusion phecode
288.3 Eosinophilia Hematopoietic 1.56 0.335 – 9.09 0.568 6 39 exclusion phecode
289 Other diseases of blood and blood-forming organs Hematopoietic 0.917 0.713 – 1.16 0.478 98 416 exclusion phecode
289.3
Personal history of diseases of blood and
Personal history of diseases of blood and blood-forming organs
 Hematopoietic 0.98 0.717 – 1.31 0.891 64 247 exclusion phecode
289.4 Lymphadenitis Hematopoietic 0.97 0.824 – 1.13 0.709 196 816 exclusion phecode
289.5 Diseases of spleen Hematopoietic 0.472 0.152 – 1.01 0.0751 13 96 exclusion phecode
289.8 Polycythemia, secondary Hematopoietic 1.31 0.545 – 2.94 0.508 10 46 exclusion phecode
289.9 Abnormality of red blood cells Hematopoietic 0.9 0.446 – 1.73 0.764 21 76 exclusion phecode
290
Delirium dementia and amnestic and other
Delirium dementia and amnestic and other cognitive disorders
 Mental Disorders 0.775 0.402 – 1.26 0.349 22 152 exclusion phecode
290.1 Dementias Mental Disorders 0.837 0.351 – 1.64 0.646 13 49 exclusion phecode
290.11 Alzheimer's disease Mental Disorders 0.665 3.06e-05 – 18 0.741 3 17 exclusion phecode
290.12 Dementia with cerebral degenerations Mental Disorders 1.08 0.697 – 2.28 1 4 4 exclusion phecode
290.13 Senile dementia Mental Disorders 0.173 0.0123 – 1.22 0.128 8 28 exclusion phecode
290.16 Vascular dementia Mental Disorders 1.03 0.859 – 1.27 1 3 5 exclusion phecode
290.2 Delirium due to conditions classified elsewhere Mental Disorders 0.582 0.191 – 1.25 0.205 12 111 exclusion phecode
290.3
Other persistent mental disorders due to
Other persistent mental disorders due to conditions classified elsewhere
 Mental Disorders 1.14 0.776 – 1.63 0.482 40 175 exclusion phecode
291
Other specified nonpsychotic and/or transient
Other specified nonpsychotic and/or transient mental disorders
 Mental Disorders 1.02 0.844 – 1.21 0.84 132 619 exclusion phecode
291.1
Transient mental disorders due to conditions
Transient mental disorders due to conditions classified elsewhere
 Mental Disorders 0.774 0.486 – 1.17 0.252 31 121 exclusion phecode
291.4
Specific nonpsychotic mental disorders due to
Specific nonpsychotic mental disorders due to brain damage
 Mental Disorders 1.39 0.868 – 2.24 0.16 18 122 exclusion phecode
291.8 Alteration of consciousness Mental Disorders 1.02 0.814 – 1.25 0.862 94 438 exclusion phecode
292 Neurological disorders Mental Disorders 0.993 0.846 – 1.16 0.928 213 930 exclusion phecode
292.1 Aphasia/speech disturbance Mental Disorders 1.06 0.759 – 1.43 0.729 50 374 exclusion phecode
292.11 Aphasia Mental Disorders 1.06 0.541 – 1.81 0.846 13 132 exclusion phecode
292.12 Symbolic dysfunction Mental Disorders 0.768 0.297 – 1.72 0.573 12 32 exclusion phecode
292.2 Mild cognitive impairment Mental Disorders 1.4 0.781 – 2.53 0.28 12 53 exclusion phecode
292.3 Memory loss Mental Disorders 1.02 0.793 – 1.29 0.888 93 359 exclusion phecode
292.4 Altered mental status Mental Disorders 1.08 0.816 – 1.39 0.587 69 405 exclusion phecode
292.5 Transient alteration of awareness Mental Disorders 1.09 0.597 – 1.85 0.756 16 105 exclusion phecode
292.6 Hallucinations Mental Disorders 1.36 0.571 – 2.74 0.38 6 56 exclusion phecode
293 Symptoms involving head and neck Mental Disorders 0.984 0.625 – 1.49 0.941 28 113 exclusion phecode
293.1
Swelling, mass, or lump in head and neck
Swelling, mass, or lump in head and neck [Space-occupying lesion, intracranial NOS]
 Mental Disorders 1.09 0.939 – 1.26 0.244 197 958 exclusion phecode
295 Schizophrenia and other psychotic disorders Mental Disorders 1.68 1.09 – 2.66 0.0247 32 88 exclusion phecode
295.1 Schizophrenia Mental Disorders 0.67 0.0505 – 2.31 0.611 5 20 exclusion phecode
295.2 Paranoid disorders Mental Disorders 1.73 0.751 – 4.71 0.276 6 21 exclusion phecode
295.3 Psychosis Mental Disorders 1.52 0.974 – 2.43 0.0805 28 76 exclusion phecode
296 Mood disorders Mental Disorders 0.99 0.856 – 1.15 0.899 687 263 exclusion phecode
296.1 Bipolar Mental Disorders 0.855 0.636 – 1.13 0.284 84 218 exclusion phecode
296.2 Depression Mental Disorders 0.981 0.846 – 1.14 0.808 666 263 exclusion phecode
296.22 Major depressive disorder Mental Disorders 0.988 0.85 – 1.15 0.882 623 263 exclusion phecode
297 Suicidal ideation or attempt Mental Disorders 1.02 0.752 – 1.35 0.897 56 180 exclusion phecode
297.1 Suicidal ideation Mental Disorders 0.835 0.561 – 1.21 0.356 46 146 exclusion phecode
297.2 Suicide or self-inflicted injury Mental Disorders 0.816 0.396 – 1.48 0.514 15 66 exclusion phecode
300 Anxiety disorders Mental Disorders 0.978 0.849 – 1.13 0.763 740 263 exclusion phecode
300.1 Anxiety disorder Mental Disorders 0.968 0.84 – 1.12 0.663 693 263 exclusion phecode
300.11 Generalized anxiety disorder Mental Disorders 0.995 0.846 – 1.17 0.95 368 263 exclusion phecode
300.12 Agorophobia, social phobia, and panic disorder Mental Disorders 1.21 0.938 – 1.55 0.147 99 217 exclusion phecode
300.13 Phobia Mental Disorders 0.953 0.679 – 1.32 0.776 65 157 exclusion phecode
300.3 Obsessive-compulsive disorders Mental Disorders 0.809 0.471 – 1.31 0.416 31 80 exclusion phecode
300.4 Dysthymic disorder Mental Disorders 1.05 0.848 – 1.31 0.642 175 243 exclusion phecode
300.8 Acute reaction to stress Mental Disorders 1.05 0.634 – 1.75 0.841 37 85 exclusion phecode
300.9 Posttraumatic stress disorder Mental Disorders 1.18 0.851 – 1.63 0.317 56 169 exclusion phecode
301 Personality disorders Mental Disorders 1.05 0.72 – 1.5 0.804 41 113 exclusion phecode
301.2 Antisocial/borderline personality disorder Mental Disorders 1.08 0.67 – 1.72 0.752 26 73 exclusion phecode
302 Sexual and gender identity disorders Mental Disorders 1.13 0.905 – 1.43 0.297 217 151 exclusion phecode
302.1 Decreased libido Mental Disorders 0.729 0.462 – 1.12 0.167 80 67 exclusion phecode
303 Psychogenic and somatoform disorders Mental Disorders 1.13 0.95 – 1.35 0.182 325 258 exclusion phecode
303.1 Dissociative disorder Mental Disorders 1.34 0.33 – 7.51 0.636 8 37 exclusion phecode
303.3 Psychogenic disorder Mental Disorders 1.15 0.968 – 1.38 0.121 305 259 exclusion phecode
303.31
Gastrointestinal malfunction arising from
Gastrointestinal malfunction arising from mental factors
 Mental Disorders 1.12 0.743 – 1.63 0.604 29 63 exclusion phecode
303.4 Somatoform disorder Mental Disorders 1.13 0.852 – 1.49 0.381 65 202 exclusion phecode
304 Adjustment reaction Mental Disorders 1.05 0.873 – 1.27 0.594 244 261 exclusion phecode
305.2 Eating disorder Mental Disorders 1.15 0.86 – 1.53 0.349 81 180 exclusion phecode
306 Other mental disorder Mental Disorders 0.909 0.725 – 1.12 0.395 151 237 exclusion phecode
306.1 Mental disorders durring/after pregnancy Mental Disorders 1.03 0.797 – 1.32 0.841 128 158 exclusion phecode
306.9 Tension headache Mental Disorders 0.933 0.666 – 1.29 0.685 73 156 exclusion phecode
312 Conduct disorders Mental Disorders 1.13 0.625 – 2.04 0.708 17 53 exclusion phecode
312.3 Impulse control disorder Mental Disorders 1.43 0.482 – 1.54 0.472 8 23 exclusion phecode
313 Pervasive developmental disorders Mental Disorders 1 0.808 – 1.22 0.987 107 488 exclusion phecode
313.1 Attention deficit hyperactivity disorder Mental Disorders 0.99 0.792 – 1.22 0.931 99 449 exclusion phecode
313.2 Tics and stuttering Mental Disorders 0.384 0.00457 – 1.83 0.305 3 19 exclusion phecode
313.3 Autism Mental Disorders 1.99 0.027 – 549 0.817 7 7 exclusion phecode
315 Develomental delays and disorders Mental Disorders 1.2 0.761 – 1.86 0.403 22 160 exclusion phecode
315.1 Learning disorder Mental Disorders 1.11 0.089 – 6.28 0.887 1 28 exclusion phecode
315.2 Speech and language disorder Mental Disorders 0.797 0.143 – 2.74 0.686 4 73 exclusion phecode
316 Substance addiction and disorders Mental Disorders 0.974 0.81 – 1.16 0.77 145 861 exclusion phecode
316.1 Polyneuropathy due to drugs Mental Disorders 1.39 0.868 – 2.17 0.157 21 169 exclusion phecode
317 Alcohol-related disorders Mental Disorders 1.01 0.767 – 1.28 0.957 62 470 exclusion phecode
317.1 Alcoholism Mental Disorders 0.993 0.738 – 1.29 0.961 50 383 exclusion phecode
317.11 Alcoholic liver damage Mental Disorders 1.06 0.254 – 2.36 0.87 4 65 exclusion phecode
318 Tobacco use disorder Mental Disorders 0.976 0.836 – 1.13 0.758 227 914 exclusion phecode
320 Meningitis Neurological 1.66 0.977 – 3 0.0523 12 107 exclusion phecode
323 Encephalitis Neurological 1.35 0.671 – 2.67 0.4 15 49 exclusion phecode
323.8 Encephalitis, non-infectious Neurological 1.29 0.612 – 2.68 0.508 14 41 exclusion phecode
324 Other CNS infection and poliomyelitis Neurological 0.487 0.0423 – 1.81 0.295 4 53 exclusion phecode
325
Phlebitis and thrombophlebitis of intracranial
Phlebitis and thrombophlebitis of intracranial venous sinuses
 Neurological 1.18 0.0621 – 191 0.896 1 15 exclusion phecode
327 Sleep disorders Neurological 0.988 0.88 – 1.11 0.844 580 684 exclusion phecode
327.1 Hypersomnia Neurological 1.07 0.867 – 1.3 0.542 143 442 exclusion phecode
327.3 Sleep apnea Neurological 1.05 0.917 – 1.2 0.477 375 680 exclusion phecode
327.31 Central/nonobstroctive sleep apnea Neurological 1.16 0.489 – 2.58 0.728 15 53 exclusion phecode
327.32 Obstructive sleep apnea Neurological 1.11 0.963 – 1.27 0.152 331 660 exclusion phecode
327.4 Insomnia Neurological 0.958 0.828 – 1.1 0.56 311 680 exclusion phecode
327.41 Organic or persistent insomnia Neurological 0.781 0.572 – 1.04 0.106 79 248 exclusion phecode
327.5 Parasomnia Neurological 1.38 0.875 – 2.19 0.178 35 96 exclusion phecode
327.6 Circadian rhythm sleep disorder Neurological 1.24 0.666 – 2.21 0.477 19 80 exclusion phecode
327.7 Sleep related movement disorders Neurological 1.1 0.851 – 1.41 0.454 90 363 exclusion phecode
327.71 Restless legs syndrome Neurological 1.14 0.856 – 1.5 0.359 73 328 exclusion phecode
327.72 Sleep related leg cramps Neurological 0.988 2.23e-05 – 8.92 0.99 2 13 exclusion phecode
331 Other cerebral degenerations Neurological 0.806 0.404 – 1.44 0.497 19 110 exclusion phecode
331.1 Hydrocephalus Neurological 0.727 0.0766 – 10.5 0.68 4 47 exclusion phecode
331.9 Cerebral degeneration, unspecified Neurological 0.761 0.343 – 1.46 0.461 15 47 exclusion phecode
332 Parkinson's disease Neurological 0.453 0.000116 – 1.84 0.311 4 47 exclusion phecode
333
Extrapyramidal disease and abnormal movement
Extrapyramidal disease and abnormal movement disorders
 Neurological 0.888 0.716 – 1.09 0.26 126 642 exclusion phecode
333.1 Essential tremor Neurological 0.76 0.379 – 1.35 0.373 17 108 exclusion phecode
333.2 Myoclonus Neurological 0.814 0.252 – 2 0.684 6 40 exclusion phecode
333.4 Torsion dystonia Neurological 0.771 0.414 – 1.28 0.355 17 83 exclusion phecode
333.8 Other degenerative diseases of the basal ganglia Neurological 0.786 0.0286 – 3.05 0.753 1 14 exclusion phecode
334 Degenerative disease of the spinal cord Neurological 1.33 0.975 – 1.83 0.0707 33 174 exclusion phecode
334.1 Spinocerebellar disease Neurological – 0 17 exclusion phecode
334.2 Anterior horn cell disease Neurological 0.956 0.0186 – 7.89 0.965 1 16 exclusion phecode
334.21 Amyotrophic Lateral Sclerosis Neurological 0.829 0.0386 – 126 0.915 1 11 exclusion phecode
335 Multiple sclerosis Neurological 1.27 0.841 – 1.89 0.246 20 120 exclusion phecode
337 Disorders of the autonomic nervous system Neurological 0.902 0.614 – 1.24 0.558 37 191 exclusion phecode
337.1 Peripheral autonomic neuropathy Neurological 1.18 0.758 – 1.72 0.426 20 82 exclusion phecode
338 Pain Neurological 1 0.894 – 1.12 0.99 690 579 exclusion phecode
338.1 Acute pain Neurological 0.984 0.869 – 1.11 0.796 489 577 exclusion phecode
338.2 Chronic pain Neurological 1.04 0.917 – 1.17 0.564 481 576 exclusion phecode
339 Other headache syndromes Neurological 0.905 0.803 – 1.02 0.1 534 633 exclusion phecode
340 Migraine Neurological 0.883 0.775 – 1 0.0614 414 606 exclusion phecode
340.1 Migrain with aura Neurological 0.836 0.706 – 0.982 0.0335 233 546 exclusion phecode
341
Other demyelinating diseases of central nervous
Other demyelinating diseases of central nervous system
 Neurological 1.11 0.517 – 2.4 0.801 7 39 exclusion phecode
342 Hemiplegia Neurological 0.781 0.371 – 1.38 0.409 16 99 exclusion phecode
343 Infantile cerebral palsy Neurological 0.33 0.000534 – 2.81 0.34 2 22 exclusion phecode
344 Other paralytic syndromes Neurological 0.842 0.488 – 1.33 0.491 23 121 exclusion phecode
345 Epilepsy, recurrent seizures, convulsions Neurological 0.965 0.763 – 1.2 0.749 91 685 exclusion phecode
345.1 Epilepsy Neurological 1.26 0.791 – 1.95 0.298 21 184 exclusion phecode
345.11 Generalized convulsive epilepsy Neurological 0.723 0.217 – 1.66 0.476 8 67 exclusion phecode
345.12 Partial epilepsy Neurological 1.57 0.943 – 2.61 0.0775 16 130 exclusion phecode
345.3 Convulsions Neurological 0.955 0.748 – 1.19 0.694 85 633 exclusion phecode
346
Abnormal findings on study of brain and/or
Abnormal findings on study of brain and/or nervous system
 Neurological 0.957 0.193 – 3.77 0.952 6 31 exclusion phecode
346.1
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of skull and head
 Neurological 1 0.736 – 1.32 0.991 60 286 exclusion phecode
346.2
Nonspecific abnormal results of function study
Nonspecific abnormal results of function study of brain and central nervous system
 Neurological 1.27 0.218 – 13.7 0.786 4 22 exclusion phecode
346.3
Nonspecific abnormal findings in cerebrospinal
Nonspecific abnormal findings in cerebrospinal fluid
 Neurological 1.72 0.116 – 15.1 0.395 5 21 exclusion phecode
347 Cataplexy and narcolepsy Neurological 0.238 0.000245 – 1.51 0.166 5 39 exclusion phecode
348 Other conditions of brain Neurological 1.1 0.81 – 1.45 0.514 47 418 exclusion phecode
348.2 Cerebral edema and compression of brain Neurological 1.13 0.733 – 1.65 0.551 22 225 exclusion phecode
348.4 Cerebral cysts Neurological 0.915 0.442 – 1.71 0.79 13 61 exclusion phecode
348.7 Coma Neurological 1.54 0.833 – 2.86 0.175 10 49 exclusion phecode
348.8 Encephalopathy, not elsewhere classified Neurological 1.13 0.669 – 1.74 0.585 16 192 exclusion phecode
348.9 Other conditions of brain, NOS Neurological 0.932 0.708 – 1.2 0.598 74 512 exclusion phecode
349
Other and unspecified disorders of the nervous
Other and unspecified disorders of the nervous system
 Neurological 0.918 0.635 – 1.27 0.622 37 231 exclusion phecode
350 Abnormal movement Neurological 1.06 0.917 – 1.21 0.443 255 981 exclusion phecode
350.1 Abnormal involuntary movements Neurological 0.976 0.808 – 1.16 0.789 149 697 exclusion phecode
350.2 Abnormality of gait Neurological 1.06 0.874 – 1.26 0.553 128 619 exclusion phecode
350.3 Lack of coordination Neurological 1.13 0.81 – 1.56 0.452 50 241 exclusion phecode
350.5 Abnormal reflex Neurological 1.83 0.703 – 6.39 0.25 7 37 exclusion phecode
350.6 Disturbances of sensation of smell and taste Neurological 0.502 0.164 – 1.1 0.103 14 110 exclusion phecode
351 Other peripheral nerve disorders Neurological 0.987 0.865 – 1.12 0.839 344 786 exclusion phecode
352 Disorders of other cranial nerves Neurological 1.09 0.843 – 1.38 0.489 60 380 exclusion phecode
352.1 Trigeminal nerve disorders [CN5] Neurological 1.12 0.803 – 1.52 0.496 29 141 exclusion phecode
352.2 Facial nerve disorders [CN7] Neurological 0.761 0.421 – 1.18 0.265 23 164 exclusion phecode
353 Nerve root and plexus disorders Neurological 0.972 0.813 – 1.15 0.748 177 739 exclusion phecode
353.1 Nerve plexus lesions Neurological 1.28 0.638 – 2.44 0.464 16 96 exclusion phecode
353.2 Nerve root lesions Neurological 0.343 0.00832 – 2.01 0.263 8 27 exclusion phecode
355 Complex regional/central pain syndrome Neurological 0.71 0.4 – 1.17 0.198 28 155 exclusion phecode
355.1 Chronic pain syndrome Neurological 0.86 0.611 – 1.17 0.355 53 210 exclusion phecode
356 Hereditary and idiopathic peripheral neuropathy Neurological 1.19 0.951 – 1.47 0.124 90 401 exclusion phecode
357 Inflammatory and toxic neuropathy Neurological 1.16 0.97 – 1.39 0.0964 116 589 exclusion phecode
358 Myoneural disorders Neurological 0.96 0.688 – 1.29 0.798 51 265 exclusion phecode
358.1 Myasthenia gravis Neurological 0.829 0.013 – 3.07 0.81 1 17 exclusion phecode
359 Muscular dystrophies and other myopathies Neurological 0.767 0.544 – 1.05 0.107 59 308 exclusion phecode
359.1 Muscular dystrophies Neurological 0.986 0.038 – 4.31 0.984 1 16 exclusion phecode
359.2 Myopathy Neurological 0.775 0.549 – 1.06 0.122 58 300 exclusion phecode
360 Disorders of the globe Sense Organs 1.63 0.797 – 4.75 0.256 10 27 exclusion phecode
360.2 Progressive myopia Sense Organs 1.38 0.262 – 8.01 0.704 5 17 exclusion phecode
361 Retinal detachments and defects Sense Organs 0.799 0.451 – 1.33 0.412 30 119 exclusion phecode
361.1 Retinal detachment with retinal defect Sense Organs 0.721 0.257 – 1.77 0.484 13 56 exclusion phecode
362 Other retinal disorders Sense Organs 0.949 0.774 – 1.15 0.604 131 364 exclusion phecode
362.2
Degeneration of macula and posterior pole of
Degeneration of macula and posterior pole of retina
 Sense Organs 0.919 0.679 – 1.22 0.573 75 201 exclusion phecode
362.21 Macular degeneration, dry Sense Organs 0.888 0.312 – 2.38 0.823 17 22 exclusion phecode
362.22 Macular degeneration, wet Sense Organs 0.853 3.97e-09 – 18100 0.97 4 8 exclusion phecode
362.23 Cystoid macular degeneration of retina Sense Organs 1.09 0.594 – 1.92 0.782 13 46 exclusion phecode
362.26 Macular puckering of retina Sense Organs 1.05 0.654 – 1.61 0.845 34 118 exclusion phecode
362.27 Drusen (degenerative) of retina Sense Organs 0.872 0.483 – 1.42 0.619 19 56 exclusion phecode
362.29 Macular degeneration (senile) of retina NOS Sense Organs 0.977 0.716 – 1.31 0.883 66 181 exclusion phecode
362.3 Other nondiabetic retinopathy Sense Organs 1.09 0.77 – 1.47 0.592 32 128 exclusion phecode
362.31 Separation of retinal layers Sense Organs 0.373 0.107 – 1 0.0697 13 60 exclusion phecode
362.4 Retinal vascular changes and abnomalities Sense Organs 0.895 0.546 – 1.4 0.65 26 79 exclusion phecode
362.6 Peripheral retinal degenerations Sense Organs 0.873 0.456 – 1.51 0.645 20 75 exclusion phecode
362.7 Hereditary retinal dystrophies Sense Organs 0.983 0.293 – 2.42 0.974 12 33 exclusion phecode
362.8 Retinal hemorrhage/ischemia Sense Organs 1.08 0.703 – 1.58 0.742 17 45 exclusion phecode
362.9 Retinal edema Sense Organs 1.25 0.694 – 2.16 0.45 11 62 exclusion phecode
363
Chorioretinal inflammations, scars, and other
Chorioretinal inflammations, scars, and other disorders of choroid
 Sense Organs 0.869 0.485 – 1.46 0.618 25 87 exclusion phecode
363.3 Chorioretinal scars Sense Organs 1.29 0.705 – 2.42 0.422 20 61 exclusion phecode
364 Corneal opacity and other disorders of cornea Sense Organs 0.771 0.49 – 1.15 0.218 39 206 exclusion phecode
364.1 Corneal opacity Sense Organs 1.16 0.729 – 1.83 0.536 25 74 exclusion phecode
364.2 Corneal edema Sense Organs 0.3 0.00142 – 2.26 0.239 5 25 exclusion phecode
364.4 Corneal degenerations Sense Organs 0.718 0.345 – 1.27 0.293 18 90 exclusion phecode
364.41 Keratoconus Sense Organs 0.91 0.0306 – 3.26 0.895 1 22 exclusion phecode
364.5 Corneal dystrophy Sense Organs 1.26 0.668 – 2.35 0.484 14 57 exclusion phecode
364.51 Fuchs' dystrophy Sense Organs 1.08 0.444 – 2.32 0.857 10 30 exclusion phecode
364.9 Cornea replaced by transplant Sense Organs 0.223 4.07e-05 – 3.31 0.29 4 15 exclusion phecode
365 Glaucoma Sense Organs 0.971 0.758 – 1.23 0.812 93 375 exclusion phecode
365.1 Open-angle glaucoma Sense Organs 0.991 0.583 – 1.6 0.973 20 80 exclusion phecode
365.11 Primary open angle glaucoma Sense Organs 0.544 0.101 – 1.51 0.304 7 40 exclusion phecode
365.2 Primary angle-closure glaucoma Sense Organs 0.616 0.191 – 1.42 0.272 10 51 exclusion phecode
366 Cataract Sense Organs 1.01 0.848 – 1.19 0.947 274 515 exclusion phecode
366.1 Nonsenile Cataract Sense Organs 2.1 0.75 – 6.94 0.179 9 25 exclusion phecode
366.2 Senile cataract Sense Organs 1.05 0.87 – 1.27 0.604 209 382 exclusion phecode
367
Disorders of refraction and accommodation
Disorders of refraction and accommodation; blindness and low vision
 Sense Organs 1.09 0.968 – 1.22 0.163 548 721 exclusion phecode
367.1 Myopia Sense Organs 1.14 1 – 1.29 0.0453 365 690 exclusion phecode
367.2 Astigmatism Sense Organs 1.03 0.892 – 1.19 0.654 277 629 exclusion phecode
367.8 Hypermetropia Sense Organs 1.01 0.802 – 1.26 0.946 127 298 exclusion phecode
367.9 Blindness and low vision Sense Organs 0.79 0.516 – 1.16 0.251 48 201 exclusion phecode
368 Visual disturbances Sense Organs 0.979 0.854 – 1.12 0.755 296 950 exclusion phecode
368.1 Amblyopia Sense Organs 0.722 0.462 – 1.05 0.113 38 147 exclusion phecode
368.2 Diplopia and disorders of binocular vision Sense Organs 0.834 0.561 – 1.16 0.315 44 202 exclusion phecode
368.3 Anisometropia Sense Organs 1.23 0.714 – 2.12 0.488 20 42 exclusion phecode
368.4 Visual field defects Sense Organs 0.903 0.638 – 1.23 0.536 42 184 exclusion phecode
368.9 Subjective visual disturbances Sense Organs 0.782 0.564 – 1.04 0.11 67 244 exclusion phecode
368.91 Psychophysical visual disturbances Sense Organs 0.786 0.586 – 0.88 0.795 5 12 exclusion phecode
369 Infection of the eye Sense Organs 0.876 0.744 – 1.02 0.102 239 692 exclusion phecode
369.2 Eye infection, viral Sense Organs 0.905 0.584 – 1.31 0.626 39 135 exclusion phecode
369.5 Conjunctivitis, infectious Sense Organs 0.884 0.745 – 1.04 0.151 212 644 exclusion phecode
370 Keratitis Sense Organs 0.851 0.655 – 1.08 0.201 85 280 exclusion phecode
370.1 Corneal ulcer Sense Organs 0.774 0.392 – 1.37 0.424 17 55 exclusion phecode
370.2 Superficial keratitis Sense Organs 1.03 0.673 – 1.49 0.873 35 98 exclusion phecode
370.3 Keratoconjunctivitis Sense Organs 1.18 0.778 – 1.74 0.42 29 123 exclusion phecode
370.31 Keratoconjunctivitis sicca Sense Organs 1.01 0.276 – 2.5 0.978 10 22 exclusion phecode
371 Inflammation of the eye Sense Organs 0.958 0.826 – 1.11 0.569 259 640 exclusion phecode
371.1 Uveitis, noninfectious or NOS Sense Organs 0.721 0.383 – 1.23 0.262 21 108 exclusion phecode
371.2 Conjunctivitis, noninfectious Sense Organs 1.01 0.769 – 1.31 0.923 81 235 exclusion phecode
371.21 Allergic conjunctivitis Sense Organs 1.07 0.808 – 1.4 0.628 69 205 exclusion phecode
371.3 Inflammation of eyelids Sense Organs 1.02 0.865 – 1.2 0.775 187 485 exclusion phecode
371.33 Noninfectious dermatoses of eyelid Sense Organs 1.47 0.799 – 2.9 0.266 16 30 exclusion phecode
372 Disorders of conjunctiva Sense Organs 1.12 0.813 – 1.51 0.451 39 169 exclusion phecode
374 Other disorders of eyelids Sense Organs 0.984 0.807 – 1.19 0.873 141 396 exclusion phecode
374.1 Ectropion or entropion Sense Organs 0.546 0.17 – 1.13 0.153 10 59 exclusion phecode
374.2 Lagophthalmos Sense Organs 1.04 0.226 – 2.33 0.923 4 46 exclusion phecode
374.3 Ptosis of eyelid Sense Organs 1.02 0.724 – 1.38 0.913 51 146 exclusion phecode
374.6 Dermatochalasis Sense Organs 0.951 0.688 – 1.27 0.754 51 107 exclusion phecode
375 Disorders of lacrimal system Sense Organs 0.939 0.786 – 1.11 0.483 209 528 exclusion phecode
375.1 Dry eyes Sense Organs 1 0.849 – 1.17 0.995 240 550 exclusion phecode
375.2 Epiphora Sense Organs 0.85 0.484 – 1.36 0.53 22 75 exclusion phecode
376 Disorders of the orbit Sense Organs 0.889 0.36 – 1.62 0.721 9 81 exclusion phecode
377 Disorders of optic nerve and visual pathways Sense Organs 0.965 0.676 – 1.31 0.834 46 172 exclusion phecode
377.1 Optic atrophy Sense Organs 1.5 0.926 – 2.52 0.131 19 49 exclusion phecode
377.3 Optic neuritis/neuropathy Sense Organs 0.903 0.542 – 1.38 0.662 26 129 exclusion phecode
378
Strabismus and other disorders of binocular eye
Strabismus and other disorders of binocular eye movements
 Sense Organs 1.03 0.761 – 1.36 0.845 58 233 exclusion phecode
378.1 Strabismus (not specified as paralytic) Sense Organs 0.776 0.512 – 1.12 0.199 44 153 exclusion phecode
378.2 Nystagmus and other irregular eye movements Sense Organs 1.17 0.614 – 2.14 0.62 10 45 exclusion phecode
378.5 Paralytic strabismus Sense Organs 1.12 0.578 – 2.1 0.744 13 47 exclusion phecode
379 Other disorders of eye Sense Organs 1.05 0.9 – 1.21 0.548 236 551 exclusion phecode
379.1 Scleritis and episcleritis Sense Organs 0.837 0.355 – 1.85 0.687 13 46 exclusion phecode
379.2 Disorders of vitreous body Sense Organs 0.966 0.781 – 1.18 0.746 151 335 exclusion phecode
379.3 Aphakia and other disorders of lens Sense Organs 1.15 0.0325 – 7.29 0.876 5 23 exclusion phecode
379.4 Anomalies of pupillary function Sense Organs 0.643 0.249 – 1.28 0.265 16 53 exclusion phecode
379.5 Disorders of iris and ciliary body Sense Organs 0.882 0.39 – 1.85 0.753 13 45 exclusion phecode
379.51 Pigmentary iris degeneration Sense Organs 0.4 0.00561 – 3.77 0.562 3 11 exclusion phecode
379.9 Pain, swelling or discharge of eye Sense Organs 0.832 0.636 – 1.06 0.161 101 258 exclusion phecode
380 Disorders of external ear Sense Organs 1.12 0.894 – 1.38 0.303 96 398 exclusion phecode
380.1 Otitis externa Sense Organs 1.07 0.878 – 1.3 0.477 111 378 exclusion phecode
380.4 Impacted cerumen Sense Organs 1.03 0.843 – 1.25 0.739 136 474 exclusion phecode
381 Otitis media and Eustachian tube disorders Sense Organs 1.01 0.873 – 1.15 0.931 273 878 exclusion phecode
381.1 Otitis media Sense Organs 1.03 0.881 – 1.2 0.69 198 802 exclusion phecode
381.11 Suppurative and unspecified otitis media Sense Organs 1.03 0.875 – 1.22 0.682 168 696 exclusion phecode
381.2 Eustachian tube disorders Sense Organs 1.06 0.86 – 1.29 0.585 131 488 exclusion phecode
381.3 Mastoiditis & related conditions Sense Organs 0.791 0.273 – 1.92 0.617 8 31 exclusion phecode
381.9 Otorrhea Sense Organs 1.6 0.911 – 2.78 0.0984 12 86 exclusion phecode
382 Otalgia Sense Organs 0.997 0.831 – 1.18 0.971 146 562 exclusion phecode
383 Otosclerosis Sense Organs 2.13 0.496 – 96.2 0.311 3 39 exclusion phecode
384 Other disorders of tympanic membrane Sense Organs 1.21 0.748 – 1.93 0.411 18 122 exclusion phecode
384.1 Myringitis Sense Organs 1.06 0.503 – 1.69 1 4 8 exclusion phecode
384.4 Perforation of tympanic membrane Sense Organs 1.29 0.674 – 2.39 0.416 12 96 exclusion phecode
385 Other disorders of middle ear and mastoid Sense Organs 1.95 1.15 – 3.41 0.0158 17 98 exclusion phecode
385.3 Cholesteatoma Sense Organs 2.34 1.15 – 6.07 0.0336 8 64 exclusion phecode
385.5
Tympanosclerosis and middle ear disease related
Tympanosclerosis and middle ear disease related to otitis media
 Sense Organs 2.93 0.984 – 64.9 0.108 3 27 exclusion phecode
386
Vertiginous syndromes and other disorders of
Vertiginous syndromes and other disorders of vestibular system
 Sense Organs 0.986 0.788 – 1.22 0.896 99 390 exclusion phecode
386.1 Meniere's disease Sense Organs 0.447 0.137 – 1.08 0.0929 11 66 exclusion phecode
386.2 Peripheral or central vertigo Sense Organs 1.02 0.788 – 1.29 0.9 84 320 exclusion phecode
386.21 Central origin vertigo Sense Organs 0.917 0.678 – 1.21 0.557 62 239 exclusion phecode
386.3 Labyrinthitis Sense Organs 0.928 0.717 – 1.18 0.552 76 309 exclusion phecode
386.9
Dizziness and giddiness (Light-headedness and
Dizziness and giddiness (Light-headedness and vertigo)
 Sense Organs 0.963 0.848 – 1.09 0.557 377 868 exclusion phecode
388 Other disorders of ear Sense Organs 0.967 0.684 – 1.34 0.843 53 257 exclusion phecode
389 Hearing loss Sense Organs 1 0.867 – 1.15 1 286 955 exclusion phecode
389.1 Sensorineural hearing loss Sense Organs 1.01 0.825 – 1.22 0.941 146 565 exclusion phecode
389.2 Conductive hearing loss Sense Organs 1.32 0.92 – 1.87 0.126 32 256 exclusion phecode
389.3 Degenerative and vascular disorders of ear Sense Organs 1.86 0.88 – 6.42 0.12 6 37 exclusion phecode
389.4 Tinnitus Sense Organs 1.12 0.888 – 1.39 0.33 110 457 exclusion phecode
389.5 Disorders of acoustic nerve Sense Organs 1.77 0.669 – 5.18 0.261 7 42 exclusion phecode
394 Rheumatic disease of the heart valves Circulatory System 1 0.712 – 1.34 0.981 38 213 exclusion phecode
394.1 Mitral valve stenosis and aortic valve stenosis Circulatory System 0.836 0.328 – 1.44 0.595 12 39 exclusion phecode
394.2 Mitral valve disease Circulatory System 1.29 0.623 – 2.51 0.467 8 62 exclusion phecode
394.3 Aortic valve disease Circulatory System 0.406 0.00131 – 1.32 0.27 4 18 exclusion phecode
394.4 Acute rheumatic heart disease Circulatory System 1.23 0.367 – 3.49 0.994 1 7 exclusion phecode
394.7 Disease of tricuspid valve Circulatory System 1.29 0.807 – 2.03 0.284 18 92 exclusion phecode
395 Heart valve disorders Circulatory System 0.892 0.707 – 1.1 0.31 106 553 exclusion phecode
395.1 Nonrheumatic mitral valve disorders Circulatory System 0.845 0.624 – 1.11 0.239 70 394 exclusion phecode
395.2 Nonrheumatic aortic valve disorders Circulatory System 0.964 0.69 – 1.27 0.809 42 223 exclusion phecode
395.3 Nonrheumatic tricuspid valve disorders Circulatory System 1.47 0.83 – 2.69 0.195 17 85 exclusion phecode
395.4 Nonrheumatic pulmonary valve disorders Circulatory System 0.67 0.0841 – 2.33 0.571 4 36 exclusion phecode
395.6 Heart valve replaced Circulatory System 1.04 0.592 – 1.7 0.876 18 129 exclusion phecode
396 Abnormal heart sounds Circulatory System 0.936 0.777 – 1.11 0.469 152 908 exclusion phecode
401 Hypertension Circulatory System 0.988 0.872 – 1.12 0.852 502 767 exclusion phecode
401.1 Essential hypertension Circulatory System 0.986 0.869 – 1.12 0.824 499 767 exclusion phecode
401.2 Hypertensive heart and/or renal disease Circulatory System 1.08 0.857 – 1.33 0.518 75 334 exclusion phecode
401.21 Hypertensive heart disease Circulatory System 1.03 0.659 – 1.48 0.879 24 114 exclusion phecode
401.22 Hypertensive chronic kidney disease Circulatory System 1.08 0.839 – 1.37 0.516 54 280 exclusion phecode
401.3 Other hypertensive complications Circulatory System 1.13 0.915 – 1.39 0.237 78 395 exclusion phecode
411 Ischemic Heart Disease Circulatory System 0.991 0.831 – 1.17 0.915 186 671 exclusion phecode
411.1 Unstable angina (intermediate coronary syndrome) Circulatory System 1.04 0.671 – 1.55 0.869 29 96 exclusion phecode
411.2 Myocardial infarction Circulatory System 1.01 0.754 – 1.32 0.936 60 340 exclusion phecode
411.3 Angina pectoris Circulatory System 1.11 0.871 – 1.4 0.378 65 268 exclusion phecode
411.4 Coronary atherosclerosis Circulatory System 1.03 0.851 – 1.23 0.763 152 553 exclusion phecode
411.41 Aneurysm and dissection of heart Circulatory System – 0 26 exclusion phecode
411.8
Other chronic ischemic heart disease
Other chronic ischemic heart disease, unspecified
 Circulatory System 1.04 0.84 – 1.26 0.716 113 463 exclusion phecode
411.9
Other acute and subacute forms of ischemic
Other acute and subacute forms of ischemic heart disease
 Circulatory System 0.959 0.303 – 2.4 0.929 6 52 exclusion phecode
414 Other forms of chronic heart disease Circulatory System 1.03 0.819 – 1.28 0.768 90 393 exclusion phecode
414.2 ASCVD Circulatory System 1.01 0.648 – 1.5 0.96 26 110 exclusion phecode
415 Pulmonary heart disease Circulatory System 0.93 0.723 – 1.16 0.538 81 603 exclusion phecode
415.1 Acute pulmonary heart disease Circulatory System 0.834 0.588 – 1.12 0.253 55 359 exclusion phecode
415.11 Pulmonary embolism and infarction, acute Circulatory System 0.827 0.58 – 1.11 0.238 54 354 exclusion phecode
415.2 Chronic pulmonary heart disease Circulatory System 1.17 0.875 – 1.51 0.251 41 312 exclusion phecode
415.21 Primary pulmonary hypertension Circulatory System 0.831 0.43 – 1.33 0.492 20 127 exclusion phecode
416 Cardiomegaly Circulatory System 1.26 0.879 – 1.77 0.201 38 216 exclusion phecode
418 Nonspecific chest pain Circulatory System 1.02 0.91 – 1.14 0.741 614 649 exclusion phecode
418.1 Precordial pain Circulatory System 1.21 0.896 – 1.62 0.213 79 159 exclusion phecode
420 Carditis Circulatory System 0.973 0.707 – 1.3 0.86 51 278 exclusion phecode
420.1 Myocarditis Circulatory System 1.64 0.589 – 8.09 0.379 2 19 exclusion phecode
420.2 Pericarditis Circulatory System 1.17 0.713 – 1.87 0.508 27 147 exclusion phecode
420.21 Acute pericarditis Circulatory System 1.11 0.38 – 2.59 0.834 7 34 exclusion phecode
420.22 Chronic pericarditis Circulatory System 1.31 0.438 – 3.99 0.629 5 19 exclusion phecode
420.3 Endocarditis Circulatory System 0.816 0.505 – 1.21 0.342 25 133 exclusion phecode
425 Cardiomyopathy Circulatory System 1.13 0.863 – 1.46 0.344 52 325 exclusion phecode
425.1 Primary/intrinsic cardiomyopathies Circulatory System 1.13 0.86 – 1.46 0.351 50 303 exclusion phecode
425.11 Hypertrophic obstructive cardiomyopathy Circulatory System 1.57 0.571 – 4.19 0.386 5 39 exclusion phecode
425.12 Other hypertrophic cardiomyopathy Circulatory System 1.19 0.0361 – 4.55 0.832 4 34 exclusion phecode
425.2 Secondary/extrinsic cardiomyopathies Circulatory System 1.66 0.765 – 3.68 0.198 10 66 exclusion phecode
425.8 Other cardiomyopathy Circulatory System 1.55 0.184 – 36.8 0.704 4 12 exclusion phecode
426 Cardiac conduction disorders Circulatory System 0.855 0.738 – 0.987 0.0348 389 584 exclusion phecode
426.2 Atrioventricular [AV] block Circulatory System 1 0.631 – 1.53 0.999 34 134 exclusion phecode
426.21 First degree AV block Circulatory System 1.1 0.634 – 1.85 0.724 25 85 exclusion phecode
426.22 Mobitz II AV block Circulatory System – 0 6 exclusion phecode
426.23 Second degree AV block Circulatory System 1.56 0.266 – 13.3 0.552 6 23 exclusion phecode
426.24 Atrioventricular block, complete Circulatory System 0.516 0.0614 – 2.5 0.36 3 51 exclusion phecode
426.25 Other heart block Circulatory System 1.08 0.08 – 24.7 0.964 3 11 exclusion phecode
426.3 Bundle branch block Circulatory System 0.98 0.682 – 1.37 0.912 45 175 exclusion phecode
426.31 Right bundle branch block Circulatory System 0.862 0.547 – 1.29 0.5 32 123 exclusion phecode
426.32 Left bundle branch block Circulatory System 1.12 0.623 – 1.87 0.689 16 78 exclusion phecode
426.4 Anomalous atrioventricular excitation Circulatory System 3.8 0.148 – 10900 0.5 2 13 exclusion phecode
426.7 Abnormal electrocardiogram [ECG] [EKG] Circulatory System 0.859 0.739 – 0.995 0.0458 362 584 exclusion phecode
426.8 Other cardiac conduction disorders Circulatory System 1.19 0.735 – 1.86 0.466 25 119 exclusion phecode
426.9 Cardiac pacemaker/device in situ Circulatory System 1.01 0.618 – 1.6 0.969 24 126 exclusion phecode
426.91 Cardiac pacemaker in situ Circulatory System 1.11 0.619 – 1.91 0.726 17 83 exclusion phecode
426.92 Cardiac defibrillator in situ Circulatory System 1.05 0.5 – 2.06 0.893 13 61 exclusion phecode
427 Cardiac dysrhythmias Circulatory System 0.901 0.801 – 1.01 0.0847 603 587 exclusion phecode
427.1 Paroxysmal tachycardia, unspecified Circulatory System 0.744 0.552 – 0.978 0.0409 82 336 exclusion phecode
427.11 Paroxysmal supraventricular tachycardia Circulatory System 0.743 0.522 – 1.02 0.0792 59 266 exclusion phecode
427.12 Paroxysmal ventricular tachycardia Circulatory System 0.679 0.401 – 1.06 0.116 34 111 exclusion phecode
427.2 Atrial fibrillation and flutter Circulatory System 0.875 0.655 – 1.15 0.351 86 279 exclusion phecode
427.21 Atrial fibrillation Circulatory System 0.888 0.663 – 1.17 0.414 84 265 exclusion phecode
427.22 Atrial flutter Circulatory System 0.834 0.532 – 1.26 0.416 38 105 exclusion phecode
427.3 Other specified cardiac dysrhythmias Circulatory System 0.925 0.794 – 1.07 0.312 288 586 exclusion phecode
427.4 Cardiac arrest and ventricular fibrillation Circulatory System 1.01 0.553 – 1.74 0.982 12 66 exclusion phecode
427.41 Ventricular fibrillation and flutter Circulatory System 0.319 0.274 – 1.17 0.143 5 26 exclusion phecode
427.42 Cardiac arrest Circulatory System 1.24 0.661 – 2.29 0.514 10 48 exclusion phecode
427.5 Arrhythmia (cardiac) NOS Circulatory System 0.863 0.72 – 1.03 0.104 223 581 exclusion phecode
427.6 Premature beats Circulatory System 0.962 0.744 – 1.23 0.761 95 265 exclusion phecode
427.61 Supraventricular premature beats Circulatory System 0.935 0.498 – 1.64 0.826 20 72 exclusion phecode
427.7 Tachycardia NOS Circulatory System 0.813 0.686 – 0.956 0.0143 250 585 exclusion phecode
427.8 Sinoatrial node dysfunction (Bradycardia) Circulatory System 0.916 0.561 – 1.41 0.707 26 85 exclusion phecode
427.9 Palpitations Circulatory System 0.913 0.785 – 1.06 0.228 293 571 exclusion phecode
428 Congestive heart failure; nonhypertensive Circulatory System 1.13 0.882 – 1.43 0.312 84 373 exclusion phecode
428.1 Congestive heart failure (CHF) NOS Circulatory System 1.11 0.848 – 1.42 0.43 71 341 exclusion phecode
428.2 Heart failure NOS Circulatory System 1.16 0.861 – 1.52 0.301 61 304 exclusion phecode
428.3
Heart failure with reduced EF [Systolic or
Heart failure with reduced EF [Systolic or combined heart failure]
 Circulatory System 1.18 0.786 – 1.67 0.379 27 162 exclusion phecode
428.4
Heart failure with preserved EF [Diastolic
Heart failure with preserved EF [Diastolic heart failure]
 Circulatory System 1.06 0.725 – 1.46 0.739 38 161 exclusion phecode
429
Ill-defined descriptions and complications of
Ill-defined descriptions and complications of heart disease
 Circulatory System 0.934 0.829 – 1.05 0.261 503 748 exclusion phecode
429.1 Heart transplant/surgery Circulatory System 0.915 0.546 – 1.46 0.721 30 136 exclusion phecode
429.2 Abnormal function study of cardiovascular system Circulatory System 0.963 0.816 – 1.13 0.652 226 653 exclusion phecode
429.3 Symptoms involving cardiovascular system Circulatory System 0.935 0.824 – 1.06 0.288 425 748 exclusion phecode
429.9 Cardiac complications, not elsewhere classified Circulatory System 1.33 0.516 – 3.16 0.514 12 88 exclusion phecode
430 Intracranial hemorrhage Circulatory System 0.497 0.227 – 0.936 0.0387 24 164 exclusion phecode
430.1 Subarachnoid hemorrhage Circulatory System 0.579 0.195 – 1.22 0.191 10 64 exclusion phecode
430.2 Intracerebral hemorrhage Circulatory System 1.16 0.439 – 2.6 0.735 11 77 exclusion phecode
430.3 Subdural hemorrhage Circulatory System 1.57 0.315 – 9.7 0.492 4 48 exclusion phecode
433 Cerebrovascular disease Circulatory System 1.06 0.872 – 1.27 0.544 125 718 exclusion phecode
433.1 Occlusion and stenosis of precerebral arteries Circulatory System 1.16 0.823 – 1.58 0.368 43 219 exclusion phecode
433.11
Occlusion of cerebral arteries, with cerebral
Occlusion of cerebral arteries, with cerebral infarction
 Circulatory System 2.09 0.887 – 48.9 0.113 5 42 exclusion phecode
433.12 Cerebral atherosclerosis Circulatory System 1.82 0.346 – 16.6 0.54 2 12 exclusion phecode
433.2 Occlusion of cerebral arteries Circulatory System 1.03 0.75 – 1.36 0.861 60 394 exclusion phecode
433.21
Cerebral artery occlusion, with cerebral
Cerebral artery occlusion, with cerebral infarction
 Circulatory System 0.976 0.706 – 1.3 0.874 58 378 exclusion phecode
433.3 Cerebral ischemia Circulatory System 1.17 0.921 – 1.46 0.178 66 398 exclusion phecode
433.31 Transient cerebral ischemia Circulatory System 1.15 0.87 – 1.47 0.299 56 351 exclusion phecode
433.5 Cerebral aneurysm Circulatory System 0.77 0.235 – 1.62 0.522 11 104 exclusion phecode
433.6 Acute, but ill-defined cerebrovascular disease Circulatory System 0.731 0.306 – 1.51 0.424 15 79 exclusion phecode
433.8 Late effects of cerebrovascular disease Circulatory System 1.04 0.566 – 1.69 0.861 18 127 exclusion phecode
440 Atherosclerosis Circulatory System 1.11 0.854 – 1.4 0.423 74 287 exclusion phecode
440.1 Atherosclerosis of renal artery Circulatory System 1.47 0.75 – 3.24 0.286 9 25 exclusion phecode
440.2 Atherosclerosis of the extremities Circulatory System 1.12 0.795 – 1.51 0.495 47 198 exclusion phecode
440.21
Atherosclerosis of native arteries of the
Atherosclerosis of native arteries of the extremities with ulceration or gangrene
 Circulatory System 0.46 0.404 – 2.35 0.411 4 25 exclusion phecode
440.22
Atherosclerosis of native arteries of the
Atherosclerosis of native arteries of the extremities with intermittent claudication
 Circulatory System 1.09 0.717 – 1.54 0.678 37 126 exclusion phecode
440.9 Atherosclerosis of aorta Circulatory System 1.09 0.645 – 1.79 0.739 27 81 exclusion phecode
441 Vascular insufficiency of intestine Circulatory System 0.93 0.466 – 1.62 0.816 18 87 exclusion phecode
441.1 Acute vascular insufficiency of intestine Circulatory System 1 0.42 – 1.95 0.993 10 46 exclusion phecode
441.2 Chronic vascular insufficiency of intestine Circulatory System 1.15 0.00315 – 27.6 0.878 3 24 exclusion phecode
442 Other aneurysm Circulatory System 1.09 0.805 – 1.44 0.581 68 323 exclusion phecode
442.1 Aortic aneurysm Circulatory System 1.22 0.866 – 1.71 0.245 47 192 exclusion phecode
442.11 Abdominal aortic aneurysm Circulatory System 1.45 0.879 – 2.37 0.14 24 106 exclusion phecode
442.2 Aneurysm of iliac artery Circulatory System 1.93 0.396 – 12.3 0.449 2 25 exclusion phecode
442.3 Aneurysm of artery of lower extremity Circulatory System 2.05 0.206 – 1150 0.408 3 31 exclusion phecode
442.4 Arterial dissection Circulatory System 1.13 0.448 – 2.53 0.791 6 34 exclusion phecode
442.8 Aneurysm of other specified artery Circulatory System 1.08 0.462 – 2.29 0.848 15 65 exclusion phecode
443 Peripheral vascular disease Circulatory System 1.02 0.822 – 1.26 0.827 103 492 exclusion phecode
443.1 Raynaud's syndrome Circulatory System 0.807 0.54 – 1.16 0.257 45 233 exclusion phecode
443.7
Peripheral angiopathy in diseases classified
Peripheral angiopathy in diseases classified elsewhere
 Circulatory System 0.8 0.239 – 2.08 0.666 6 33 exclusion phecode
443.8 Other specified peripheral vascular diseases Circulatory System 1.04 0.816 – 1.3 0.741 87 414 exclusion phecode
443.9 Peripheral vascular disease, unspecified Circulatory System 1.14 0.865 – 1.48 0.326 58 271 exclusion phecode
444 Arterial embolism and thrombosis Circulatory System 1.22 0.82 – 1.71 0.285 28 160 exclusion phecode
444.1
Arterial embolism and thrombosis of lower
Arterial embolism and thrombosis of lower extremity artery
 Circulatory System 1.26 0.582 – 2.64 0.547 8 57 exclusion phecode
444.2 Embolism and thrombosis of abdominal aorta Circulatory System 6.15 0.103 – 530 0.31 3 21 exclusion phecode
446 Polyarteritis nodosa and allied conditions Circulatory System 1.18 0.62 – 2.15 0.605 19 80 exclusion phecode
446.4 Wegener's granulomatosis Circulatory System 0.843 0.161 – 5.86 0.845 4 15 exclusion phecode
446.5 Giant cell arteritis Circulatory System – 0 6 exclusion phecode
446.9 Arteritis NOS Circulatory System 1.1 0.495 – 2.31 0.809 14 60 exclusion phecode
447 Other disorders of arteries and arterioles Circulatory System 0.82 0.602 – 1.08 0.179 76 396 exclusion phecode
447.1 Stricture of artery Circulatory System 0.408 0.106 – 1.13 0.112 11 80 exclusion phecode
447.7 Aortic ectasia Circulatory System 1.15 0.668 – 1.93 0.601 27 102 exclusion phecode
448 Disease of capillaries Circulatory System 0.98 0.712 – 1.3 0.893 48 274 exclusion phecode
450 Noninfectious disorders of lymphatic channels Circulatory System 1.16 0.942 – 1.4 0.151 103 521 exclusion phecode
451 Phlebitis and thrombophlebitis Circulatory System 0.72 0.435 – 1.09 0.146 31 143 exclusion phecode
451.2
Phlebitis and thrombophlebitis of lower
Phlebitis and thrombophlebitis of lower extremities
 Circulatory System 1.25 0.578 – 2.51 0.531 9 50 exclusion phecode
452 Other venous embolism and thrombosis Circulatory System 0.955 0.776 – 1.16 0.654 129 624 exclusion phecode
452.1 Iatrogenic pulmonary embolism and infarction Circulatory System 0.52 0.212 – 1.02 0.0909 21 55 exclusion phecode
452.2 Deep vein thrombosis [DVT] Circulatory System 0.996 0.776 – 1.26 0.976 78 501 exclusion phecode
452.8 Postphlebitic syndrome Circulatory System 0.556 0.156 – 1.39 0.248 6 30 exclusion phecode
453 Chronic venous hypertension Circulatory System 1.65 0.908 – 3.24 0.13 15 41 exclusion phecode
454 Varicose veins Circulatory System 1.09 0.898 – 1.31 0.389 157 458 exclusion phecode
454.1 Varicose veins of lower extremity Circulatory System 1.09 0.887 – 1.32 0.414 131 415 exclusion phecode
454.11 Varicose veins of lower extremity, symptomtic Circulatory System 1.05 0.831 – 1.31 0.687 98 282 exclusion phecode
455 Hemorrhoids Circulatory System 0.991 0.849 – 1.15 0.902 285 655 exclusion phecode
456 Chronic venous insufficiency [CVI] Circulatory System 1.1 0.93 – 1.29 0.27 184 523 exclusion phecode
457
Encounter for long-term (current) use of
Encounter for long-term (current) use of anticoagulants, antithrombotics, aspirin
 Circulatory System 1.02 0.657 – 1.53 0.919 37 185 exclusion phecode
457.2
Encounter for long-term (current) use of
Encounter for long-term (current) use of antiplatelets/antithrombotics
 Circulatory System 0.712 0.0295 – 3.79 0.733 4 27 exclusion phecode
457.3 Encounter for long-term (current) use of aspirin Circulatory System 1.04 0.664 – 1.57 0.86 35 174 exclusion phecode
458 Hypotension Circulatory System 0.927 0.769 – 1.1 0.408 167 793 exclusion phecode
458.1 Orthostatic hypotension Circulatory System 1 0.741 – 1.32 0.976 63 268 exclusion phecode
458.2 Iatrogenic hypotension Circulatory System 0.751 0.458 – 1.13 0.201 33 171 exclusion phecode
458.9 Hypotension NOS Circulatory System 0.928 0.761 – 1.12 0.445 147 738 exclusion phecode
459 Other disorders of circulatory system Circulatory System 1.06 0.917 – 1.22 0.422 242 912 exclusion phecode
459.1 Hemorrhage NOS Circulatory System 1.02 0.714 – 1.41 0.919 39 181 exclusion phecode
459.7 Blood vessel replaced Circulatory System 1.01 0.652 – 1.47 0.952 29 243 exclusion phecode
459.9 Circulatory disease NEC Circulatory System 1.07 0.914 – 1.24 0.394 203 860 exclusion phecode
464 Acute sinusitis Respiratory 0.99 0.862 – 1.13 0.885 384 505 exclusion phecode
465
Acute upper respiratory infections of multiple
Acute upper respiratory infections of multiple or unspecified sites
 Respiratory 0.973 0.868 – 1.09 0.645 675 529 exclusion phecode
465.2 Acute pharyngitis Respiratory 0.992 0.871 – 1.13 0.901 454 512 exclusion phecode
465.4 Acute laryngitis and tracheitis Respiratory 1.15 0.713 – 1.85 0.552 27 74 exclusion phecode
470 Septal Deviations/Turbinate Hypertrophy Respiratory 1.02 0.773 – 1.31 0.895 83 295 exclusion phecode
471 Nasal polyps Respiratory 0.799 0.428 – 1.37 0.449 24 97 exclusion phecode
472 Chronic pharyngitis and nasopharyngitis Respiratory 1 0.799 – 1.24 0.99 121 303 exclusion phecode
473 Diseases of the larynx and vocal cords Respiratory 0.906 0.702 – 1.15 0.433 98 385 exclusion phecode
473.1 Chronic laryngitis Respiratory 1.21 0.0518 – 47.2 0.925 2 8 exclusion phecode
473.3 Paralysis/spasm of vocal cords or larynx Respiratory 0.621 0.313 – 1.13 0.136 21 91 exclusion phecode
473.4 Voice disturbance Respiratory 0.908 0.668 – 1.21 0.518 68 302 exclusion phecode
474 Acute and chronic tonsillitis Respiratory 0.793 0.566 – 1.08 0.158 59 250 exclusion phecode
474.1 Acute tonsillitis Respiratory 0.614 0.329 – 1.04 0.0904 28 115 exclusion phecode
474.2 Chronic tonsillitis and adenoiditis Respiratory 0.817 0.559 – 1.15 0.27 45 206 exclusion phecode
475 Chronic sinusitis Respiratory 0.928 0.781 – 1.1 0.392 268 459 exclusion phecode
475.9 Postnasal drip Respiratory 0.887 0.622 – 1.23 0.495 57 156 exclusion phecode
476 Allergic rhinitis Respiratory 0.998 0.882 – 1.13 0.981 617 462 exclusion phecode
477 Epistaxis or throat hemorrhage Respiratory 1.21 0.879 – 1.66 0.24 57 180 exclusion phecode
478 Throat pain Respiratory 1 0.59 – 1.62 0.996 28 80 exclusion phecode
479 Other upper respiratory disease Respiratory 1.02 0.878 – 1.19 0.765 280 462 exclusion phecode
480 Pneumonia Respiratory 1.1 0.947 – 1.27 0.21 234 795 exclusion phecode
480.1 Bacterial pneumonia Respiratory 1.03 0.733 – 1.42 0.851 42 185 exclusion phecode
480.11 Pneumococcal pneumonia Respiratory 1.41 0.934 – 2.13 0.115 29 91 exclusion phecode
480.12 Pseudomonal pneumonia Respiratory 2.02 0.657 – 44 0.251 3 22 exclusion phecode
480.13 MRSA pneumonia Respiratory 0.987 0.302 – 5.96 0.983 6 17 exclusion phecode
480.2 Viral pneumonia Respiratory 0.68 0.142 – 1.98 0.477 6 37 exclusion phecode
480.3 Pneumonia due to fungus (mycoses) Respiratory 0.775 0.304 – 1.93 0.606 10 25 exclusion phecode
480.5 Bronchopneumonia and lung abscess Respiratory – 0 13 exclusion phecode
481 Influenza Respiratory 1.07 0.851 – 1.32 0.573 108 353 exclusion phecode
483 Acute bronchitis and bronchiolitis Respiratory 1.01 0.869 – 1.17 0.9 257 669 exclusion phecode
495 Asthma Respiratory 0.917 0.807 – 1.04 0.178 386 776 exclusion phecode
495.1 Chronic obstructive asthma Respiratory 0.863 0.459 – 1.41 0.588 16 85 exclusion phecode
495.11 Chronic obstructive asthma with exacerbation Respiratory 1.24 0.145 – 6.62 0.814 5 19 exclusion phecode
495.2 Asthma with exacerbation Respiratory 1.09 0.921 – 1.29 0.3 146 512 exclusion phecode
496 Chronic airway obstruction Respiratory 0.97 0.776 – 1.19 0.777 107 561 exclusion phecode
496.1 Emphysema Respiratory 0.89 0.585 – 1.28 0.548 38 271 exclusion phecode
496.2 Chronic bronchitis Respiratory 1.01 0.791 – 1.27 0.923 80 477 exclusion phecode
496.21 Obstructive chronic bronchitis Respiratory 0.938 0.702 – 1.22 0.644 63 426 exclusion phecode
496.3 Bronchiectasis Respiratory 0.922 0.47 – 1.58 0.784 19 87 exclusion phecode
497 Bronchitis Respiratory 0.99 0.805 – 1.2 0.922 118 446 exclusion phecode
498 Acute bronchospasm Respiratory 1.02 0.72 – 1.4 0.93 38 130 exclusion phecode
499 Cystic fibrosis Respiratory 1.07 0.524 – 2.06 0.833 14 70 exclusion phecode
500 Lung disease due to external agents Respiratory 0.622 0.288 – 1.15 0.165 21 89 exclusion phecode
500.1 Extrinsic allergic alveolitis Respiratory 1.11 0.127 – 57.2 0.926 5 19 exclusion phecode
500.2 Pneumoconiosis Respiratory 0.91 0.0014 – 686 0.999 1 8 exclusion phecode
501 Pneumonitis due to inhalation of food or vomitus Respiratory 1.51 0.577 – 3.87 0.348 7 86 exclusion phecode
502 Postinflammatory pulmonary fibrosis Respiratory 1.35 0.874 – 2.05 0.167 27 149 exclusion phecode
503 Pulmonary congestion and hypostasis Respiratory 1.06 0.696 – 1.48 0.75 23 145 exclusion phecode
504 Other alveolar and parietoalveolar pneumonopathy Respiratory 1.37 0.795 – 2.28 0.244 15 93 exclusion phecode
504.1 Idiopathic fibrosing alveolitis Respiratory 1.26 0.519 – 2.77 0.576 6 47 exclusion phecode
505 Other pulmonary inflamation or edema Respiratory 0.895 0.63 – 1.2 0.494 46 268 exclusion phecode
506 Empyema and pneumothorax Respiratory 0.917 0.662 – 1.22 0.568 54 482 exclusion phecode
507 Pleurisy; pleural effusion Respiratory 0.889 0.686 – 1.12 0.339 83 569 exclusion phecode
508
Pulmonary collapse; interstitial and
Pulmonary collapse; interstitial and compensatory emphysema
 Respiratory 0.833 0.622 – 1.08 0.186 72 458 exclusion phecode
509 Respiratory failure, insufficiency, arrest Respiratory 0.863 0.663 – 1.09 0.24 83 604 exclusion phecode
509.1 Respiratory failure Respiratory 1.12 0.822 – 1.48 0.444 43 349 exclusion phecode
509.2 Respiratory insufficiency Respiratory 0.754 0.456 – 1.14 0.21 30 207 exclusion phecode
509.3
Pulmonary insufficiency or respiratory failure
Pulmonary insufficiency or respiratory failure following trauma and surgery
 Respiratory 0.688 0.397 – 1.08 0.125 32 264 exclusion phecode
509.8
Dependence on respirator [Ventilator] or
Dependence on respirator [Ventilator] or supplemental oxygen
 Respiratory 0.992 0.68 – 1.37 0.962 35 289 exclusion phecode
510 Other diseases of lung Respiratory 1.05 0.899 – 1.21 0.543 211 810 exclusion phecode
510.2 Lung transplant Respiratory 0.787 0.297 – 1.72 0.6 8 24 exclusion phecode
512 Other symptoms of respiratory system Respiratory 0.965 0.859 – 1.09 0.553 804 465 exclusion phecode
512.1 Wheezing Respiratory 1.37 1.08 – 1.75 0.0125 97 200 exclusion phecode
512.2 Painful respiration Respiratory 0.959 0.784 – 1.17 0.684 167 365 exclusion phecode
512.3 Abnormal chest sounds Respiratory 1.17 0.615 – 2.26 0.665 17 27 exclusion phecode
512.7 Shortness of breath Respiratory 0.969 0.845 – 1.11 0.656 468 465 exclusion phecode
512.8 Cough Respiratory 1.02 0.896 – 1.15 0.806 541 465 exclusion phecode
512.9 Other dyspnea Respiratory 0.972 0.849 – 1.11 0.687 464 465 exclusion phecode
513 Respiratory abnormalities Respiratory 0.983 0.876 – 1.1 0.772 530 739 exclusion phecode
513.3 Hypoventilation Respiratory 1.12 0.857 – 1.45 0.39 48 149 exclusion phecode
513.31 Apnea Respiratory 1.14 0.764 – 1.66 0.532 25 80 exclusion phecode
513.32 Orthopnea Respiratory 0.911 0.398 – 2.04 0.84 12 23 exclusion phecode
513.4 Hyperventilation Respiratory 1.04 0.618 – 1.53 0.853 19 86 exclusion phecode
513.8 Disorders of diaphragm Respiratory 0.24 0.0139 – 1.11 0.11 9 35 exclusion phecode
514 Abnormal findings examination of lungs Respiratory 1.01 0.846 – 1.2 0.885 151 811 exclusion phecode
514.1
Abnormal results of function study of pulmonary
Abnormal results of function study of pulmonary system
 Respiratory 0.733 0.308 – 1.42 0.402 10 44 exclusion phecode
514.2 Solitary pulmonary nodule Respiratory 0.886 0.681 – 1.13 0.337 87 539 exclusion phecode
516 Abnormal sputum Respiratory 1.28 0.837 – 1.83 0.22 24 162 exclusion phecode
516.1 Hemoptysis Respiratory 1.29 0.829 – 1.89 0.221 22 143 exclusion phecode
519
Other diseases of respiratory system, not
Other diseases of respiratory system, not elsewhere classified
 Respiratory 0.953 0.817 – 1.1 0.523 231 1004 exclusion phecode
519.1 Tracheostomy complications Respiratory – 0 27 exclusion phecode
519.2 Respiratory complications Respiratory 0.829 0.24 – 1.61 0.593 7 71 exclusion phecode
519.8 Other diseases of respiratory system, NEC Respiratory 1.07 0.824 – 1.34 0.598 63 366 exclusion phecode
519.9
Symptoms involving respiratory system and other
Symptoms involving respiratory system and other chest symptoms
 Respiratory 0.912 0.755 – 1.09 0.324 160 800 exclusion phecode
520 Disorders of tooth development Digestive 1.23 0.581 – 2.35 0.512 8 99 exclusion phecode
520.1 Hereditary disturbances in tooth structure Digestive 2.05 0.515 – 153 0.219 3 48 exclusion phecode
520.2 Disturbances in tooth eruption Digestive 1.37 0.501 – 3.51 0.499 5 56 exclusion phecode
521 Diseases of hard tissues of teeth Digestive 1.01 0.611 – 1.56 0.953 22 228 exclusion phecode
521.1 Dental caries Digestive 1.01 0.556 – 1.65 0.962 18 219 exclusion phecode
521.2 Dental abrasion, erosion and attrition Digestive 0.534 0.00195 – 14.6 0.722 3 15 exclusion phecode
522 Diseases of pulp and periapical tissues Digestive 0.873 0.54 – 1.34 0.558 30 171 exclusion phecode
522.5 Periapical abscess Digestive 0.902 0.556 – 1.4 0.656 28 143 exclusion phecode
523 Gingival and periodontal diseases Digestive 1.2 0.816 – 1.73 0.347 31 178 exclusion phecode
523.1 Gingivitis Digestive 0.614 0.1 – 2.51 0.521 5 36 exclusion phecode
523.3 Periodontitis (acute or chronic) Digestive 0.626 0.27 – 1.28 0.221 17 100 exclusion phecode
523.31 Acute periodontitis Digestive 0.583 0.24 – 1.21 0.175 16 82 exclusion phecode
523.32 Chronic periodontitis Digestive 0.734 0.00379 – 3.42 0.727 2 19 exclusion phecode
524 Dentofacial anomalies, including malocclusion Digestive 1.04 0.528 – 1.79 0.9 9 116 exclusion phecode
524.3 Anomalies of tooth position/malocclusion Digestive 1.43 0.635 – 3.33 0.368 5 60 exclusion phecode
525
Other diseases of the teeth and supporting
Other diseases of the teeth and supporting structures
 Digestive 1 0.654 – 1.45 0.991 30 303 exclusion phecode
525.1 Loss of teeth or edentulism Digestive 1.54 0.858 – 2.84 0.146 14 94 exclusion phecode
526 Diseases of the jaws Digestive 1.15 0.966 – 1.35 0.109 136 824 exclusion phecode
526.1 Cysts of the jaws Digestive 0.354 0.0274 – 1.45 0.164 5 61 exclusion phecode
526.3 Anomalies of jaw size/symmetry Digestive 1.11 0.473 – 2.23 0.787 8 67 exclusion phecode
526.4 Temporomandibular joint disorders Digestive 1.11 0.899 – 1.35 0.31 95 535 exclusion phecode
526.41 Temporomandibular joint disorder, unspecified Digestive 1.22 0.995 – 1.5 0.0531 81 447 exclusion phecode
526.42 Arthralgia/ankylosis of temporomandibular joint Digestive 1.06 0.742 – 1.42 0.74 38 285 exclusion phecode
526.5 Inflammatory conditions of jaw Digestive 1.27 0.331 – 4.02 0.628 3 58 exclusion phecode
526.8 Exostosis of jaw Digestive 0.989 0.616 – 1.73 1 1 9 exclusion phecode
526.9 Jaw disease NOS Digestive 1.36 0.766 – 2.29 0.267 19 120 exclusion phecode
527 Diseases of the salivary glands Digestive 1.1 0.836 – 1.41 0.48 66 400 exclusion phecode
527.1 Hypertrophy of salivary gland Digestive 1.25 0.345 – 63.4 0.789 2 14 exclusion phecode
527.2 Sialoadenitis Digestive 1.23 0.799 – 1.82 0.335 23 102 exclusion phecode
527.7 Disturbance of salivary secretion Digestive 0.762 0.427 – 1.23 0.284 26 202 exclusion phecode
527.8 Other specified diseases of the salivary glands Digestive 1.46 0.777 – 3.39 0.248 9 51 exclusion phecode
528
Diseases of the oral soft tissues, excluding
Diseases of the oral soft tissues, excluding lesions specific for gingiva and tongue
 Digestive 1.01 0.825 – 1.22 0.906 118 649 exclusion phecode
528.1 Stomatitis and mucositis Digestive 0.756 0.489 – 1.11 0.168 40 183 exclusion phecode
528.11 Stomatitis and mucositis (ulcerative) Digestive 0.756 0.32 – 1.59 0.484 13 56 exclusion phecode
528.12 Oral aphthae Digestive 0.774 0.365 – 1.33 0.398 15 82 exclusion phecode
528.3 Cellulitis and abscess of oral soft tissues Digestive 0.899 0.419 – 1.66 0.755 12 58 exclusion phecode
528.4 Cysts of oral soft tissues Digestive 1.79 0.374 – 23.4 0.505 3 26 exclusion phecode
528.41 Cyst of the salivary gland Digestive 2.9 0.444 – 70.1 0.34 1 18 exclusion phecode
528.5 Diseases of lips Digestive 1.11 0.738 – 1.64 0.597 30 125 exclusion phecode
528.6 Leukoplakia of oral mucosa Digestive 1.77 0.557 – 28.6 0.349 1 26 exclusion phecode
528.7 Sialolithiasis Digestive 1.51 0.527 – 4.31 0.394 8 40 exclusion phecode
529 Diseases and other conditions of the tongue Digestive 1.24 0.93 – 1.63 0.145 29 146 exclusion phecode
529.1 Glossitis Digestive 1.67 0.978 – 3.71 0.0932 7 35 exclusion phecode
529.6 Glossodynia Digestive 1.01 0.488 – 1.87 0.976 7 40 exclusion phecode
530 Diseases of esophagus Digestive 0.991 0.884 – 1.11 0.878 611 621 exclusion phecode
530.1 Esophagitis, GERD and related diseases Digestive 0.992 0.884 – 1.11 0.889 603 621 exclusion phecode
530.11 GERD Digestive 0.995 0.887 – 1.12 0.934 589 621 exclusion phecode
530.12 Ulcer of esophagus Digestive 1.2 0.606 – 2.26 0.577 11 70 exclusion phecode
530.13 Barrett's esophagus Digestive 1.63 1.07 – 2.54 0.0306 24 83 exclusion phecode
530.14 Reflux esophagitis Digestive 1.08 0.863 – 1.34 0.491 108 342 exclusion phecode
530.15 Eosinophilic esophagitis Digestive 0.884 0.429 – 1.68 0.718 18 65 exclusion phecode
530.2 Esophageal bleeding (varices/hemorrhage) Digestive 0.882 0.408 – 1.62 0.703 14 100 exclusion phecode
530.3 Stricture and stenosis of esophagus Digestive 0.999 0.65 – 1.49 0.998 33 137 exclusion phecode
530.5 Disorders of esophageal motility Digestive 0.911 0.537 – 1.44 0.704 24 108 exclusion phecode
530.6 Diverticulum of esophagus, acquired Digestive – 0 8 exclusion phecode
530.7 Gastroesophageal laceration-hemorrhage syndrome Digestive 0.822 0.0547 – 3.79 0.81 3 20 exclusion phecode
530.9 Heartburn Digestive 1.23 0.978 – 1.53 0.0732 85 346 exclusion phecode
531 Peptic ulcer (excl. esophageal) Digestive 1.01 0.775 – 1.28 0.949 84 489 exclusion phecode
531.1 Hemorrhage from gastrointestinal ulcer Digestive 0.64 0.261 – 1.38 0.303 13 66 exclusion phecode
531.2 Gastric ulcer Digestive 1 0.714 – 1.33 0.988 48 278 exclusion phecode
531.3 Duodenal ulcer Digestive 0.721 0.334 – 1.34 0.331 15 98 exclusion phecode
531.4 Peptic ulcer, site unspecified Digestive 0.885 0.561 – 1.31 0.563 39 204 exclusion phecode
531.5 Gastrojejunal ulcer Digestive 0.623 0.0503 – 1.84 0.459 4 43 exclusion phecode
532 Dysphagia Digestive 1.03 0.869 – 1.22 0.718 195 602 exclusion phecode
535 Gastritis and duodenitis Digestive 1 0.826 – 1.2 0.997 137 652 exclusion phecode
535.1 Acute gastritis Digestive 0.861 0.608 – 1.16 0.349 52 263 exclusion phecode
535.2 Atrophic gastritis Digestive 1.16 0.683 – 1.85 0.516 18 88 exclusion phecode
535.6 Duodenitis Digestive 0.502 0.204 – 0.959 0.0652 17 58 exclusion phecode
535.8 Other specified gastritis Digestive 0.852 0.484 – 1.34 0.522 29 159 exclusion phecode
535.9 Gastritis and duodenitis, NOS Digestive 1.05 0.819 – 1.32 0.687 74 341 exclusion phecode
536 Disorders of function of stomach Digestive 0.967 0.815 – 1.14 0.693 184 707 exclusion phecode
536.3 Gastroparesis Digestive 0.97 0.661 – 1.34 0.86 38 228 exclusion phecode
536.7
Complications of gastrostomy, colostomy and
Complications of gastrostomy, colostomy and enterostomy
 Digestive 1.04 0.528 – 1.86 0.898 12 77 exclusion phecode
536.8
Dyspepsia and other specified disorders of
Dyspepsia and other specified disorders of function of stomach
 Digestive 0.963 0.8 – 1.15 0.678 161 553 exclusion phecode
537 Other disorders of stomach and duodenum Digestive 1.02 0.855 – 1.2 0.832 167 692 exclusion phecode
537.1 Lesions of stomach and duodenum Digestive 0.462 2.63e-05 – 1.64 0.352 3 23 exclusion phecode
539 Bariatric surgery Digestive 0.94 0.73 – 1.18 0.607 83 556 exclusion phecode
540 Appendiceal conditions Digestive 1.06 0.698 – 1.54 0.783 26 155 exclusion phecode
540.1 Appendicitis Digestive 0.969 0.629 – 1.42 0.875 23 135 exclusion phecode
540.11 Acute appendicitis Digestive 0.911 0.533 – 1.43 0.702 19 115 exclusion phecode
550 Abdominal hernia Digestive 0.948 0.808 – 1.1 0.5 209 949 exclusion phecode
550.1 Inguinal hernia Digestive 1.06 0.778 – 1.4 0.677 43 213 exclusion phecode
550.2 Diaphragmatic hernia Digestive 0.922 0.726 – 1.14 0.479 98 573 exclusion phecode
550.3 Femoral hernia Digestive 1.39 0.518 – 5.86 0.516 4 29 exclusion phecode
550.4 Umbilical hernia Digestive 0.814 0.584 – 1.08 0.186 57 260 exclusion phecode
550.5 Ventral hernia Digestive 0.889 0.658 – 1.16 0.402 57 476 exclusion phecode
550.6 Incisional hernia Digestive 0.876 0.586 – 1.24 0.468 34 295 exclusion phecode
555
Inflammatory bowel disease and other
Inflammatory bowel disease and other gastroenteritis and colitis
 Digestive 1.05 0.807 – 1.36 0.687 72 323 exclusion phecode
555.1 Regional enteritis Digestive 0.776 0.518 – 1.11 0.188 42 187 exclusion phecode
555.2 Ulcerative colitis Digestive 1.03 0.759 – 1.39 0.827 48 197 exclusion phecode
555.21 Ulcerative colitis (chronic) Digestive 1.04 0.718 – 1.48 0.825 33 122 exclusion phecode
556 Ulceration of the lower GI tract Digestive 0.876 0.518 – 1.35 0.592 25 71 exclusion phecode
556.1 Ulceration of intestine Digestive 0.868 0.506 – 1.34 0.567 25 61 exclusion phecode
556.11
Angiodysplasia of intestine (without mention of
Angiodysplasia of intestine (without mention of hemorrhage)
 Digestive 0.963 0.000463 – 3.39 0.939 6 17 exclusion phecode
557 Intestinal malabsorption (non-celiac) Digestive 1.04 0.853 – 1.25 0.703 118 439 exclusion phecode
557.1 Celiac disease Digestive 0.964 0.637 – 1.38 0.852 35 125 exclusion phecode
558 Noninfectious gastroenteritis Digestive 1.05 0.9 – 1.23 0.505 200 550 exclusion phecode
559 Ileostomy status Digestive 0.75 0.427 – 1.22 0.265 27 163 exclusion phecode
560 Intestinal obstruction without mention of hernia Digestive 0.936 0.731 – 1.17 0.581 91 445 exclusion phecode
560.1 Paralytic ileus Digestive 1.11 0.753 – 1.55 0.571 32 214 exclusion phecode
560.2 Impaction of intestine Digestive 0.958 0.623 – 1.37 0.833 32 86 exclusion phecode
560.3 Peritoneal or intestinal adhesions Digestive 1.15 0.535 – 2.25 0.699 8 43 exclusion phecode
560.4 Other intestinal obstruction Digestive 0.806 0.561 – 1.11 0.204 48 262 exclusion phecode
561 Symptoms involving digestive system Digestive 1 0.826 – 1.2 0.991 138 483 exclusion phecode
562 Diverticulosis and diverticulitis Digestive 0.983 0.811 – 1.18 0.859 211 371 exclusion phecode
562.1 Diverticulosis Digestive 0.981 0.809 – 1.18 0.844 208 369 exclusion phecode
562.2 Diverticulitis Digestive 0.975 0.697 – 1.31 0.877 45 179 exclusion phecode
564 Functional digestive disorders Digestive 1.02 0.905 – 1.16 0.707 497 565 exclusion phecode
564.1 Irritable Bowel Syndrome Digestive 1.06 0.899 – 1.24 0.498 211 520 exclusion phecode
564.9 Personal history of diseases of digestive system Digestive 1.07 0.879 – 1.3 0.474 124 497 exclusion phecode
565 Anal and rectal conditions Digestive 0.979 0.818 – 1.16 0.81 163 661 exclusion phecode
565.1 Anal and rectal polyp Digestive 1.05 0.766 – 1.43 0.739 59 196 exclusion phecode
567 Peritonitis and retroperitoneal infections Digestive 0.833 0.559 – 1.18 0.328 46 237 exclusion phecode
568 Other disorders of peritoneum Digestive 0.909 0.618 – 1.25 0.584 44 324 exclusion phecode
568.1
Peritoneal adhesions (postoperative)
Peritoneal adhesions (postoperative) (postinfection)
 Digestive 0.948 0.602 – 1.32 0.777 28 226 exclusion phecode
569 Other disorders of intestine Digestive 0.938 0.818 – 1.07 0.347 333 819 exclusion phecode
569.1 Toxic gastroenteritis and colitis Digestive 1.17 0.613 – 2.14 0.617 18 83 exclusion phecode
569.2 Gastrointestinal complications Digestive 1.08 0.809 – 1.4 0.565 49 295 exclusion phecode
571 Chronic liver disease and cirrhosis Digestive 0.847 0.704 – 1.01 0.0707 179 727 exclusion phecode
571.5 Other chronic nonalcoholic liver disease Digestive 0.852 0.706 – 1.02 0.0828 173 710 exclusion phecode
571.51 Cirrhosis of liver without mention of alcohol Digestive 1.02 0.639 – 1.47 0.922 23 190 exclusion phecode
571.6 Primary biliary cirrhosis Digestive 0.578 0.135 – 1.73 0.356 7 37 exclusion phecode
571.8
Liver abscess and sequelae of chronic liver
Liver abscess and sequelae of chronic liver disease
 Digestive 0.873 0.503 – 1.41 0.59 20 168 exclusion phecode
571.81 Portal hypertension Digestive 0.313 0.0943 – 0.77 0.0178 13 102 exclusion phecode
572 Ascites (non malignant) Digestive 0.847 0.628 – 1.11 0.248 77 456 exclusion phecode
573 Other disorders of liver Digestive 0.823 0.69 – 0.971 0.0244 214 777 exclusion phecode
573.1 Chronic passive congestion of liver Digestive 0.928 0.153 – 3.28 0.918 3 23 exclusion phecode
573.2 Liver replaced by transplant Digestive 0.455 0.132 – 1.09 0.111 7 53 exclusion phecode
573.3 Hepatomegaly Digestive 0.728 0.347 – 1.35 0.332 17 117 exclusion phecode
573.4 Acute and subacute necrosis of liver Digestive 1.71 0.722 – 4 0.193 6 63 exclusion phecode
573.5 Jaundice (not of newborn) Digestive 0.583 0.337 – 0.932 0.0333 33 163 exclusion phecode
573.6
Nonspecific elevation of levels of transaminase
Nonspecific elevation of levels of transaminase or lactic acid dehydrogenase [LDH]
 Digestive 0.858 0.692 – 1.05 0.146 140 512 exclusion phecode
573.7 Abnormal results of function study of liver Digestive 0.958 0.797 – 1.14 0.635 167 542 exclusion phecode
573.9 Abnormal serum enzyme levels Digestive 0.967 0.829 – 1.12 0.665 218 775 exclusion phecode
574 Cholelithiasis and cholecystitis Digestive 0.918 0.761 – 1.09 0.351 157 839 exclusion phecode
574.1 Cholelithiasis Digestive 0.929 0.767 – 1.11 0.431 148 806 exclusion phecode
574.11 Cholelithiasis with acute cholecystitis Digestive 1.06 0.599 – 1.82 0.831 22 90 exclusion phecode
574.12 Cholelithiasis with other cholecystitis Digestive 0.777 0.448 – 1.25 0.324 30 165 exclusion phecode
574.2 Calculus of bile duct Digestive 1.18 0.819 – 1.62 0.337 33 240 exclusion phecode
574.3 Cholecystitis without cholelithiasis Digestive 0.94 0.631 – 1.35 0.747 45 213 exclusion phecode
575 Other biliary tract disease Digestive 0.999 0.815 – 1.21 0.995 118 593 exclusion phecode
575.1 Cholangitis Digestive 1.27 0.506 – 2.88 0.569 6 80 exclusion phecode
575.2 Obstruction of bile duct Digestive 1.05 0.51 – 1.82 0.873 15 139 exclusion phecode
575.6 Cholesterolosis of gallbladder Digestive 1.1 0.59 – 1.97 0.762 14 57 exclusion phecode
575.7 Other disorders of gallbladder Digestive 1.11 0.864 – 1.38 0.408 65 267 exclusion phecode
575.8 Other disorders of biliary tract Digestive 0.771 0.487 – 1.15 0.217 40 272 exclusion phecode
575.9
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of biliary tract
 Digestive 1.02 0.443 – 2.1 0.97 11 61 exclusion phecode
577 Diseases of pancreas Digestive 0.738 0.543 – 0.973 0.0375 77 516 exclusion phecode
577.1 Acute pancreatitis Digestive 0.594 0.372 – 0.887 0.0149 44 317 exclusion phecode
577.2 Chronic pancreatitis Digestive 0.578 0.252 – 1.14 0.128 17 120 exclusion phecode
577.3 Cyst and pseudocyst of pancreas Digestive 1.4 0.821 – 2.31 0.202 20 119 exclusion phecode
578 Gastrointestinal hemorrhage Digestive 0.931 0.797 – 1.08 0.358 241 824 exclusion phecode
578.1 Hematemesis Digestive 0.917 0.496 – 1.54 0.754 21 104 exclusion phecode
578.2 Blood in stool Digestive 0.914 0.749 – 1.1 0.36 146 552 exclusion phecode
578.8 Hemorrhage of rectum and anus Digestive 0.948 0.766 – 1.15 0.611 125 523 exclusion phecode
578.9 Hemorrhage of gastrointestinal tract Digestive 0.918 0.643 – 1.26 0.615 54 272 exclusion phecode
579 Other symptoms involving abdomen and pelvis Digestive 0.904 0.765 – 1.06 0.227 218 781 exclusion phecode
579.2 Splenomegaly Digestive 0.612 0.345 – 0.991 0.0566 26 160 exclusion phecode
579.8 Nonspecific abnormal findings in stool contents Digestive 1.05 0.791 – 1.38 0.707 65 296 exclusion phecode
580 Nephritis; nephrosis; renal sclerosis Genitourinary 1.14 0.919 – 1.41 0.224 73 323 exclusion phecode
580.1 Glomerulonephritis Genitourinary 0.884 0.434 – 1.4 0.656 14 85 exclusion phecode
580.11 Proliferative glomerulonephritis Genitourinary 0.977 0.404 – 1.56 0.939 8 24 exclusion phecode
580.12 Non-proliferative glomerulonephritis Genitourinary 0.989 0.305 – 1.64 0.973 4 29 exclusion phecode
580.13 Acute glomerulonephritis, NOS Genitourinary 0.479 0.443 – 4.45 0.627 4 10 exclusion phecode
580.14 Chronic glomerulonephritis, NOS Genitourinary 0.312 0.0305 – 1.18 0.122 8 55 exclusion phecode
580.2
Nephrotic syndrome without mention of
Nephrotic syndrome without mention of glomerulonephritis
 Genitourinary 0.541 0.131 – 1.43 0.29 10 46 exclusion phecode
580.3
Nephritis and nephropathy without mention of
Nephritis and nephropathy without mention of glomerulonephritis
 Genitourinary 1.06 0.843 – 1.32 0.605 67 255 exclusion phecode
580.31
Nephritis and nephropathy in diseases
Nephritis and nephropathy in diseases classified elsewhere
 Genitourinary 1.06 0.819 – 1.36 0.659 48 153 exclusion phecode
580.32
Nephritis and nephropathy with pathological
Nephritis and nephropathy with pathological lesion
 Genitourinary 0.889 0.582 – 1.24 0.531 32 155 exclusion phecode
580.4 Renal sclerosis, NOS Genitourinary 1.09 0.497 – 2.04 0.802 9 68 exclusion phecode
585 Renal failure Genitourinary 0.964 0.812 – 1.13 0.665 178 786 exclusion phecode
585.1 Acute renal failure Genitourinary 0.996 0.802 – 1.22 0.971 105 558 exclusion phecode
585.2 Renal failure NOS Genitourinary 0.809 0.449 – 1.26 0.392 23 151 exclusion phecode
585.3 Chronic renal failure [CKD] Genitourinary 0.993 0.816 – 1.19 0.943 125 632 exclusion phecode
585.31 Renal dialysis Genitourinary 1.09 0.615 – 1.61 0.701 12 138 exclusion phecode
585.32 End stage renal disease Genitourinary 1.03 0.708 – 1.4 0.85 25 184 exclusion phecode
585.33 Chronic Kidney Disease, Stage III Genitourinary 0.996 0.763 – 1.27 0.978 65 364 exclusion phecode
585.34 Chronic Kidney Disease, Stage IV Genitourinary 1.15 0.807 – 1.58 0.409 24 143 exclusion phecode
585.4 Chronic kidney disease, Stage I or II Genitourinary 0.977 0.679 – 1.31 0.888 35 192 exclusion phecode
586 Other disorders of the kidney and ureters Genitourinary 1.02 0.88 – 1.17 0.798 246 884 exclusion phecode
586.1 Anatomical abnormatilies of kidney and ureters Genitourinary 1.43 0.827 – 2.43 0.197 14 86 exclusion phecode
586.11 Small kidney Genitourinary 1.8 0.621 – 10.3 0.3 5 37 exclusion phecode
586.12 Vesicoureteral reflux Genitourinary 1.57 0.748 – 3.41 0.257 10 42 exclusion phecode
586.2 Cyst of kidney, acquired Genitourinary 1 0.712 – 1.35 0.978 42 191 exclusion phecode
586.3 Vascular disorders of kidney/hypertrophy Genitourinary 0.407 0.00253 – 3.3 0.437 4 29 exclusion phecode
586.4 Stricture/obstruction of ureter Genitourinary 1.3 0.995 – 1.67 0.0491 55 327 exclusion phecode
587 Kidney replaced by transpant Genitourinary 0.42 0.17 – 0.874 0.0249 20 166 exclusion phecode
588 Disorders resulting from impaired renal function Genitourinary 0.888 0.588 – 1.24 0.522 34 171 exclusion phecode
588.1 Renal osteodystrophy Genitourinary 0.799 0.276 – 1.47 0.556 9 53 exclusion phecode
588.2 Secondary hyperparathyroidism (of renal origin) Genitourinary 0.928 0.593 – 1.32 0.712 30 122 exclusion phecode
589 Abnormal results of function study of kidney Genitourinary 0.922 0.626 – 1.27 0.642 37 200 exclusion phecode
590 Pyelonephritis Genitourinary 1.05 0.828 – 1.3 0.686 91 385 exclusion phecode
591 Urinary tract infection Genitourinary 0.944 0.836 – 1.06 0.347 494 665 exclusion phecode
592 Cystitis and urethritis Genitourinary 0.974 0.804 – 1.17 0.78 159 580 exclusion phecode
592.1 Cystitis Genitourinary 0.947 0.774 – 1.15 0.585 149 567 exclusion phecode
592.11 Acute cystitis Genitourinary 1.01 0.792 – 1.26 0.966 101 387 exclusion phecode
592.12 Chronic cystitis Genitourinary 1.67 0.895 – 3.33 0.127 14 65 exclusion phecode
592.13 Chronic interstitial cystitis Genitourinary 0.939 0.591 – 1.43 0.782 34 138 exclusion phecode
592.2 Urethritis and urethral syndrome Genitourinary 1.64 0.844 – 3.42 0.159 16 60 exclusion phecode
593 Hematuria Genitourinary 0.967 0.826 – 1.13 0.674 227 648 exclusion phecode
593.1 Gross hematuria Genitourinary 0.712 0.478 – 1.01 0.0702 58 210 exclusion phecode
593.2 Microscopic hematuria Genitourinary 0.944 0.701 – 1.23 0.689 58 198 exclusion phecode
594 Urinary calculus Genitourinary 0.959 0.818 – 1.11 0.591 205 1030 exclusion phecode
594.1 Calculus of kidney Genitourinary 0.954 0.809 – 1.11 0.557 190 1028 exclusion phecode
594.2 Calculus of lower urinary tract Genitourinary 1.06 0.352 – 2.84 0.901 11 55 exclusion phecode
594.3 Calculus of ureter Genitourinary 0.955 0.709 – 1.25 0.75 59 324 exclusion phecode
594.8 Renal colic Genitourinary 1.21 0.803 – 1.78 0.369 21 114 exclusion phecode
595 Hydronephrosis Genitourinary 1.11 0.827 – 1.43 0.435 50 435 exclusion phecode
596 Other disorders of bladder Genitourinary 1.05 0.849 – 1.28 0.629 98 648 exclusion phecode
596.1 Bladder neck obstruction Genitourinary 0.798 0.253 – 1.74 0.636 5 37 exclusion phecode
596.5 Functional disorders of bladder Genitourinary 1.06 0.818 – 1.34 0.632 70 414 exclusion phecode
597 Other disorders of urethra and urinary tract Genitourinary 1.2 0.868 – 1.61 0.235 34 210 exclusion phecode
597.1 Urethral stricture (not specified as infectious) Genitourinary 1.63 0.796 – 3.39 0.172 13 77 exclusion phecode
597.2 Urinary complications NEC Genitourinary 0.694 0.381 – 1.14 0.169 23 194 exclusion phecode
597.8 Urethral hypermobility/ISD Genitourinary 1.51 0.627 – 3.65 0.274 5 49 exclusion phecode
598 Abnormal findings on examination of urine Genitourinary 0.839 0.236 – 2.45 0.778 10 20 exclusion phecode
598.4 Other cells and casts in urine Genitourinary 0.245 0.0113 – 1.23 0.156 9 20 exclusion phecode
599 Other symptoms/disorders or the urinary system Genitourinary 1 0.893 – 1.12 0.979 618 622 exclusion phecode
599.1 Urinary obstruction Genitourinary 1.27 0.718 – 2.21 0.416 18 54 exclusion phecode
599.2 Retention of urine Genitourinary 0.81 0.64 – 1.01 0.0666 129 542 exclusion phecode
599.3 Dysuria Genitourinary 0.934 0.799 – 1.09 0.392 281 594 exclusion phecode
599.4 Urinary incontinence Genitourinary 1.02 0.865 – 1.2 0.79 215 565 exclusion phecode
599.5 Frequency of urination and polyuria Genitourinary 0.986 0.849 – 1.14 0.849 278 598 exclusion phecode
599.6 Oliguria and anuria Genitourinary 0.586 0.115 – 1.69 0.354 8 67 exclusion phecode
599.7 Urethral discharge Genitourinary 0.716 0.00294 – 4.2 0.757 7 10 exclusion phecode
599.8 Other symptoms involving urinary system Genitourinary 1.06 0.905 – 1.24 0.458 225 584 exclusion phecode
599.9 Other abnormality of urination Genitourinary 1.05 0.866 – 1.25 0.624 147 502 exclusion phecode
600 Hyperplasia of prostate Genitourinary 0.9 0.611 – 1.27 0.574 70 78 exclusion phecode
601 Inflammatory diseases of prostate Genitourinary 0.674 0.409 – 1.01 0.0814 41 83 exclusion phecode
601.1 Prostatitis Genitourinary 0.426 0.115 – 1.1 0.117 18 35 exclusion phecode
601.11 Acute prostatitis Genitourinary 1.38 0.137 – 12.5 0.839 5 8 exclusion phecode
601.12 Chronic prostatitis Genitourinary 0.682 0.661 – 0.705 0.842 1 10 exclusion phecode
601.3 Orchitis and epididymitis Genitourinary 0.73 0.303 – 1.42 0.414 18 33 exclusion phecode
601.4 Balanoposthitis Genitourinary 1.71 0.555 – 7.41 0.444 7 11 exclusion phecode
601.8
Other inflammatory disorders of male genital
Other inflammatory disorders of male genital organs
 Genitourinary 0.795 0.00219 – 1.38 0.573 8 6 exclusion phecode
602 Other disorders of prostate Genitourinary 1.02 0.093 – 3 0.981 7 16 exclusion phecode
602.3 Dysplasia of prostate Genitourinary – 0 3 exclusion phecode
603 Other disorders of testis Genitourinary 0.6 0.0921 – 2.31 0.525 11 16 exclusion phecode
603.1 Hydrocele Genitourinary 0.361 0.0264 – 2.14 0.373 8 13 exclusion phecode
603.2 Spermatocele Genitourinary 0.97 0.958 – 1.18 0.987 3 7 exclusion phecode
604 Disorders of penis Genitourinary 1.63 0.837 – 3.43 0.2 26 24 exclusion phecode
604.1 Redundant prepuce and phimosis/BXO Genitourinary 0.27 0.000107 – 654 0.971 2 6 exclusion phecode
604.3 Peyronie's disease Genitourinary 1.81 0.321 – 84.3 0.596 9 6 exclusion phecode
605 Erectile dysfunction [ED] Genitourinary 1.49 0.962 – 2.51 0.0964 132 42 exclusion phecode
608 Other disorders of male genital organs Genitourinary 1.17 0.791 – 1.8 0.462 63 47 exclusion phecode
609 Male infertility and abnormal spermatozoa Genitourinary 1.1 0.726 – 2 0.69 60 20 exclusion phecode
609.1 Infertility, male Genitourinary 0.915 0.562 – 1.71 0.748 48 11 exclusion phecode
609.11 Azoospermia and oligospermia Genitourinary 1.33 0.458 – 9.63 0.664 23 4 exclusion phecode
609.2 Abnormal spermatozoa Genitourinary 1 0.37 – 3.49 1 17 7 exclusion phecode
610 Benign mammary dysplasias Genitourinary 0.954 0.799 – 1.14 0.605 258 445 exclusion phecode
610.1 Cystic mastopathy Genitourinary 1.08 0.849 – 1.36 0.542 110 315 exclusion phecode
610.2 Fibroadenosis of breast Genitourinary 4.53 0.754 – 5.15 0.173 6 17 exclusion phecode
610.4 Benign neoplasm of breast Genitourinary 0.992 0.82 – 1.2 0.935 189 440 exclusion phecode
610.8 Other specified benign mammary dysplasias Genitourinary 1.13 0.842 – 1.49 0.408 64 263 exclusion phecode
611 Abnormal findings on mammogram or breast exam Genitourinary 1.06 0.919 – 1.21 0.443 460 475 exclusion phecode
611.1 Abnormal mammogram Genitourinary 1.03 0.879 – 1.21 0.698 376 432 exclusion phecode
611.11 Mammographic microcalcification Genitourinary 1.6 1.19 – 2.17 0.00283 70 148 exclusion phecode
611.3 Lump or mass in breast Genitourinary 1.14 0.977 – 1.33 0.0997 299 472 exclusion phecode
612
Breast conditions, congenital or relating to
Breast conditions, congenital or relating to hormones
 Genitourinary 0.962 0.757 – 1.2 0.741 111 315 exclusion phecode
612.1 Galactorrhea Genitourinary 1.02 0.607 – 1.68 0.943 26 54 exclusion phecode
612.2 Hypertrophy of breast (Gynecomastia) Genitourinary 0.869 0.623 – 1.16 0.373 73 209 exclusion phecode
612.3 Congenital anomalies of breast Genitourinary 0.972 0.306 – 3.11 0.964 8 23 exclusion phecode
613 Other nonmalignant breast conditions Genitourinary 1.11 0.966 – 1.26 0.143 320 728 exclusion phecode
613.1 Inflammatory disease of breast Genitourinary 0.933 0.643 – 1.32 0.707 55 218 exclusion phecode
613.5 Mastodynia Genitourinary 1.17 0.98 – 1.4 0.0799 174 556 exclusion phecode
613.7 Other signs and symptoms in breast Genitourinary 1.03 0.802 – 1.31 0.794 93 319 exclusion phecode
613.8 Other specified disorders of breast Genitourinary 1.36 1.07 – 1.74 0.0126 62 311 exclusion phecode
613.9 Breast disorder NOS Genitourinary 1.4 1.13 – 1.72 0.0021 95 396 exclusion phecode
614 Inflammatory diseases of female pelvic organs Genitourinary 0.969 0.852 – 1.1 0.631 422 544 exclusion phecode
614.1
Pelvic peritoneal adhesions, female
Pelvic peritoneal adhesions, female (postoperative) (postinfection)
 Genitourinary 0.834 0.557 – 1.2 0.358 41 110 exclusion phecode
614.3 Pelvic inflammatory disease (PID) Genitourinary 1.02 0.741 – 1.38 0.906 68 187 exclusion phecode
614.31 Acute inflammatory pelvic disease Genitourinary 0.644 0.264 – 1.26 0.251 17 45 exclusion phecode
614.32 Chronic inflammatory pelvic disease Genitourinary 1.31 0.762 – 2.28 0.345 30 63 exclusion phecode
614.33 Pelvic inflammatory disease, NOS Genitourinary 1.13 0.683 – 1.82 0.63 25 89 exclusion phecode
614.4 Inflammatory diseases of uterus, except cervix Genitourinary 0.893 0.555 – 1.39 0.636 37 69 exclusion phecode
614.5
Inflammatory disease of cervix, vagina, and
Inflammatory disease of cervix, vagina, and vulva
 Genitourinary 0.997 0.872 – 1.14 0.967 358 544 exclusion phecode
614.51 Cervicitis and endocervicitis Genitourinary 1.17 0.834 – 1.64 0.384 31 88 exclusion phecode
614.52 Vaginitis and vulvovaginitis Genitourinary 0.989 0.855 – 1.14 0.876 308 543 exclusion phecode
614.53 Cyst or abscess of Bartholin's gland Genitourinary 0.928 0.422 – 1.82 0.838 15 54 exclusion phecode
614.54 Abscess or ulceration of vulva Genitourinary 1.21 0.862 – 1.65 0.261 22 80 exclusion phecode
615 Endometriosis Genitourinary 0.927 0.758 – 1.12 0.445 147 476 exclusion phecode
618 Genital prolapse Genitourinary 1.04 0.845 – 1.27 0.684 108 618 exclusion phecode
618.1 Prolapse of vaginal walls Genitourinary 0.95 0.685 – 1.27 0.737 51 378 exclusion phecode
618.2 Uterine/Uterovaginal prolapse Genitourinary 0.971 0.576 – 1.53 0.906 21 135 exclusion phecode
618.5 Prolapse of vaginal vault after hysterectomy Genitourinary 0.884 0.144 – 2.53 0.827 3 63 exclusion phecode
618.6 Vaginal enterocele, congenital or acquired Genitourinary 0.99 0.587 – 1.57 0.968 17 131 exclusion phecode
619 Noninflammatory female genital disorders Genitourinary 0.99 0.873 – 1.12 0.878 590 432 exclusion phecode
619.1
Noninflammatory disorders of ovary, fallopian
Noninflammatory disorders of ovary, fallopian tube, and broad ligament
 Genitourinary 0.819 0.662 – 1 0.06 168 336 exclusion phecode
619.2 Disorders of uterus, NEC Genitourinary 1.12 0.862 – 1.45 0.413 95 153 exclusion phecode
619.3 Noninflammatory disorders of cervix Genitourinary 1.2 0.914 – 1.57 0.196 59 143 exclusion phecode
619.4 Noninflammatory disorders of vagina Genitourinary 0.965 0.826 – 1.13 0.659 295 429 exclusion phecode
619.5 Noninflammatory disorders of vulva and perineum Genitourinary 1.07 0.866 – 1.31 0.538 105 283 exclusion phecode
620 Dysplasia of female genital organs Genitourinary 1.13 0.762 – 1.64 0.53 29 139 exclusion phecode
620.1 Dysplasia of cervix Genitourinary 1.15 0.738 – 1.69 0.513 19 82 exclusion phecode
621 Endometrial hyperplasia Genitourinary 1.11 0.825 – 1.47 0.483 48 144 exclusion phecode
622 Polyp of female genital organs Genitourinary 1.03 0.872 – 1.22 0.713 205 465 exclusion phecode
622.1 Polyp of corpus uteri Genitourinary 1.06 0.88 – 1.26 0.561 170 367 exclusion phecode
622.2 Mucous polyp of cervix Genitourinary 0.981 0.687 – 1.37 0.913 49 129 exclusion phecode
623 Hypertrophy of female genital organs Genitourinary 1.09 0.842 – 1.4 0.491 72 288 exclusion phecode
624 Symptoms involving female genital tract Genitourinary 1.01 0.829 – 1.23 0.916 170 337 exclusion phecode
624.1 Dystrophy of female genital tract Genitourinary 2.1 0.976 – 5.53 0.11 12 27 exclusion phecode
624.2 Atrophy of female genital tract Genitourinary 0.679 0.528 – 3.87 0.761 4 7 exclusion phecode
624.9 stress incontinence, female Genitourinary 1.26 1.03 – 1.53 0.0235 126 319 exclusion phecode
625
Pain and other symptoms associated with female
Pain and other symptoms associated with female genital organs
 Genitourinary 1.05 0.924 – 1.21 0.439 554 392 exclusion phecode
625.1 Dyspareunia Genitourinary 1.12 0.907 – 1.37 0.292 107 334 exclusion phecode
626
Disorders of menstruation and other abnormal
Disorders of menstruation and other abnormal bleeding from female genital tract
 Genitourinary 0.896 0.74 – 1.1 0.269 790 102 exclusion phecode
626.1 Irregular menstrual cycle/bleeding Genitourinary 0.909 0.75 – 1.12 0.344 652 98 exclusion phecode
626.11 Absent or infrequent menstruation Genitourinary 0.85 0.662 – 1.1 0.208 243 78 exclusion phecode
626.12 Excessive or frequent menstruation Genitourinary 0.95 0.768 – 1.19 0.649 277 91 exclusion phecode
626.13 Irregular menstrual cycle Genitourinary 0.918 0.742 – 1.14 0.436 353 90 exclusion phecode
626.14 Irregular menstrual bleeding Genitourinary 0.975 0.745 – 1.28 0.855 137 71 exclusion phecode
626.15 Infertility, female, associated with anovulation Genitourinary 0.767 0.545 – 1.09 0.134 197 37 exclusion phecode
626.2 Dysmenorrhea Genitourinary 0.868 0.678 – 1.12 0.271 191 80 exclusion phecode
626.4 Premenstrual tension syndromes Genitourinary 0.629 0.358 – 1.01 0.0834 50 27 exclusion phecode
626.8 Infertility, female Genitourinary 0.77 0.608 – 0.982 0.0325 364 66 exclusion phecode
627 Menopausal and postmenopausal disorders Genitourinary 0.811 0.642 – 1.03 0.0829 401 93 exclusion phecode
627.1 Postmenopausal bleeding Genitourinary 1.17 0.778 – 1.8 0.478 90 48 exclusion phecode
627.2 Symptomatic menopause Genitourinary 0.817 0.624 – 1.08 0.148 265 79 exclusion phecode
627.21 Symptomatic artificial menopause Genitourinary 1.15 0.068 – 7.96 0.853 12 8 exclusion phecode
627.22
Need for Hormone replacement therapy
Need for Hormone replacement therapy (postmenopausal)
 Genitourinary 0.99 0.529 – 1.93 0.977 32 14 exclusion phecode
627.3 Postmenopausal atrophic vaginitis Genitourinary 0.927 0.561 – 1.5 0.763 54 53 exclusion phecode
627.4 Premenopausal menorrhagia Genitourinary 1.08 0.665 – 1.79 0.772 59 26 exclusion phecode
627.5 Premature menopause and other ovarian failure Genitourinary 0.61 0.365 – 0.989 0.0561 81 22 exclusion phecode
628 Ovarian cyst Genitourinary 0.818 0.639 – 1.05 0.114 270 96 exclusion phecode
634 Miscarriage; stillbirth Pregnancy Complications 0.998 0.83 – 1.19 0.987 173 352 exclusion phecode
634.1 Missed abortion/Hydatidiform mole Pregnancy Complications 1.04 0.793 – 1.37 0.755 84 158 exclusion phecode
634.3 Ectopic pregnancy Pregnancy Complications 1.1 0.695 – 1.67 0.696 25 53 exclusion phecode
635
Hemorrhage during pregnancy; childbirth and
Hemorrhage during pregnancy; childbirth and postpartum
 Pregnancy Complications 1.06 0.844 – 1.31 0.629 128 290 exclusion phecode
635.2
Antepartum hemorrhage, abruptio placentae, and
Antepartum hemorrhage, abruptio placentae, and placenta previa
 Pregnancy Complications 0.992 0.751 – 1.29 0.956 84 198 exclusion phecode
635.3 Placenta previa and abruptio placenta Pregnancy Complications 1.05 0.791 – 1.38 0.74 76 152 exclusion phecode
636
Early or threatened labor; hemorrhage in early
Early or threatened labor; hemorrhage in early pregnancy
 Pregnancy Complications 1.08 0.919 – 1.27 0.347 240 370 exclusion phecode
636.1 Threatened premature labor Pregnancy Complications 1.17 0.909 – 1.5 0.224 85 210 exclusion phecode
636.2 Early onset of delivery Pregnancy Complications 0.92 0.637 – 1.25 0.626 50 151 exclusion phecode
636.3 Hemorrhage in early pregnancy Pregnancy Complications 1.23 0.975 – 1.56 0.0853 114 219 exclusion phecode
636.8 Cervical incompetence Pregnancy Complications 1.34 0.777 – 2.34 0.323 19 43 exclusion phecode
637
Short gestation; low birth weight; and fetal
Short gestation; low birth weight; and fetal growth retardation
 Pregnancy Complications 1.14 0.443 – 2.87 0.791 6 23 exclusion phecode
642
Hypertension complicating pregnancy
Hypertension complicating pregnancy, childbirth, and the puerperium
 Pregnancy Complications 1.02 0.832 – 1.24 0.842 131 389 exclusion phecode
642.1 Preeclampsia and eclampsia Pregnancy Complications 0.801 0.577 – 1.08 0.164 64 207 exclusion phecode
643 Excessive vomiting in pregnancy Pregnancy Complications 1.26 0.922 – 1.72 0.142 42 183 exclusion phecode
643.1 Hyperemesis gravidarum Pregnancy Complications 1.75 1.05 – 2.97 0.0346 17 95 exclusion phecode
644 Anemia during pregnancy Pregnancy Complications 1.1 0.81 – 1.49 0.525 54 173 exclusion phecode
646 Other complications of pregnancy NEC Pregnancy Complications 1.09 0.916 – 1.29 0.338 195 400 exclusion phecode
647
Infectious and parasitic complications
Infectious and parasitic complications affecting pregnancy
 Pregnancy Complications 1.26 0.907 – 1.75 0.171 30 161 exclusion phecode
647.1
Infections of genitourinary tract during
Infections of genitourinary tract during pregnancy
 Pregnancy Complications 1.05 0.754 – 1.44 0.771 45 168 exclusion phecode
647.3 Major puerperal infection Pregnancy Complications 0.971 0.496 – 1.79 0.93 17 53 exclusion phecode
649
Other conditions or status of the mother
Other conditions or status of the mother complicating pregnancy, childbirth, or the puerperium
 Pregnancy Complications 1.09 0.933 – 1.27 0.284 265 403 exclusion phecode
649.1
Diabetes or abnormal glucose tolerance
Diabetes or abnormal glucose tolerance complicating pregnancy
 Pregnancy Complications 1.01 0.807 – 1.24 0.952 113 284 exclusion phecode
653
Problems associated with amniotic cavity and
Problems associated with amniotic cavity and membranes
 Pregnancy Complications 1.2 0.974 – 1.46 0.0879 121 382 exclusion phecode
654.1
Abnormality of organs and soft tissues of
Abnormality of organs and soft tissues of pelvis complicating pregnancy, childbirth, or the puerperium
 Pregnancy Complications 1.23 0.897 – 1.69 0.204 56 141 exclusion phecode
654.2 Rhesus isoimmunization in pregnancy Pregnancy Complications 0.912 0.579 – 1.36 0.672 32 134 exclusion phecode
655
Known or suspected fetal abnormality affecting
Known or suspected fetal abnormality affecting management of mother
 Pregnancy Complications 0.967 0.834 – 1.12 0.66 309 468 exclusion phecode
655.1 Abnormality in fetal heart rate or rhythm Pregnancy Complications 0.964 0.765 – 1.2 0.746 119 300 exclusion phecode
656 Other perinatal conditions of fetus or newborn Pregnancy Complications 1.06 0.886 – 1.27 0.514 192 364 exclusion phecode
656.2 Respiratory conditions of fetus and newborn Pregnancy Complications 0.968 0.296 – 2.98 0.958 7 18 exclusion phecode
669 Complications of labor and delivery NEC Pregnancy Complications 1.08 0.91 – 1.29 0.368 192 418 exclusion phecode
671
Venous/cerebrovascular complications embolism
Venous/cerebrovascular complications embolism in pregnancy and the puerperium
 Pregnancy Complications 1.03 0.64 – 1.6 0.888 29 128 exclusion phecode
674 Other complications of the puerperium NEC Pregnancy Complications 0.994 0.606 – 1.57 0.979 30 90 exclusion phecode
676
Other disorders of the breast associated with
Other disorders of the breast associated with childbirth and disorders of lactation
 Pregnancy Complications 1.05 0.739 – 1.46 0.799 55 148 exclusion phecode
681 Superficial cellulitis and abscess Dermatologic 1.05 0.923 – 1.2 0.442 314 858 exclusion phecode
681.1 Cellulitis and abscess of fingers/toes Dermatologic 1.11 0.883 – 1.38 0.363 77 271 exclusion phecode
681.2 Cellulitis and abscess of face/neck Dermatologic 1.03 0.76 – 1.36 0.865 59 194 exclusion phecode
681.3 Cellulitis and abscess of arm/hand Dermatologic 1.07 0.854 – 1.32 0.559 107 390 exclusion phecode
681.5 Cellulitis and abscess of leg, except foot Dermatologic 1.09 0.876 – 1.36 0.424 103 394 exclusion phecode
681.6 Cellulitis and abscess of foot, toe Dermatologic 1.16 0.918 – 1.47 0.208 84 319 exclusion phecode
681.7 Cellulitis and abscess of trunk Dermatologic 1.08 0.831 – 1.37 0.569 70 336 exclusion phecode
686
Other local infections of skin and subcutaneous
Other local infections of skin and subcutaneous tissue
 Dermatologic 1.03 0.833 – 1.26 0.768 116 429 exclusion phecode
686.1 Carbuncle and furuncle Dermatologic 1.08 0.707 – 1.61 0.707 43 135 exclusion phecode
686.2 Impetigo Dermatologic 1.24 0.814 – 1.84 0.315 30 127 exclusion phecode
686.3 Pilonidal cyst Dermatologic 1.15 0.521 – 2.34 0.707 5 56 exclusion phecode
686.4 Pyogenic granuloma Dermatologic 0.81 0.252 – 2.05 0.684 13 37 exclusion phecode
686.5 Pyoderma Dermatologic – 0 18 exclusion phecode
687 Symptoms affecting skin Dermatologic 0.971 0.757 – 1.23 0.81 100 296 exclusion phecode
687.1 Rash and other nonspecific skin eruption Dermatologic 0.966 0.851 – 1.09 0.592 448 618 exclusion phecode
687.3 Changes in skin texture Dermatologic 0.497 0.226 – 0.904 0.0369 20 79 exclusion phecode
687.4 Disturbance of skin sensation Dermatologic 0.98 0.857 – 1.12 0.771 349 618 exclusion phecode
689 Disorder of skin and subcutaneous tissue NOS Dermatologic 0.96 0.853 – 1.08 0.501 490 776 exclusion phecode
690 Erythematosquamous dermatosis Dermatologic 1.05 0.904 – 1.21 0.521 270 600 exclusion phecode
690.1 Seborrheic dermatitis Dermatologic 1.05 0.902 – 1.21 0.547 270 599 exclusion phecode
691 Congenital anomalies of skin Dermatologic 0.849 0.561 – 1.22 0.391 39 162 exclusion phecode
691.3 Congenital pigmentary anomalies of skin Dermatologic 0.779 0.225 – 2.41 0.689 8 25 exclusion phecode
694 Dyschromia and Vitiligo Dermatologic 0.92 0.739 – 1.13 0.439 134 356 exclusion phecode
694.1 Vitiligo Dermatologic 0.657 0.192 – 1.71 0.449 8 33 exclusion phecode
694.2 Other dyschromia Dermatologic 0.933 0.747 – 1.14 0.526 124 328 exclusion phecode
694.3 Vascular disorders of skin Dermatologic 0.622 0.00794 – 4.84 0.728 5 13 exclusion phecode
695 Erythematous conditions Dermatologic 1.15 0.993 – 1.33 0.0614 243 663 exclusion phecode
695.1 Toxic erythema Dermatologic 1.03 0.219 – 3.74 0.973 8 16 exclusion phecode
695.2 Bullous dermatoses Dermatologic 1.33 0.0029 – 87.7 0.906 3 9 exclusion phecode
695.3 Rosacea Dermatologic 1.18 0.978 – 1.43 0.0851 129 347 exclusion phecode
695.4 Lupus (localized and systemic) Dermatologic 1.1 0.745 – 1.59 0.623 39 146 exclusion phecode
695.41 Cutaneous lupus erythematosus Dermatologic 1.03 0.578 – 1.73 0.917 22 62 exclusion phecode
695.42 Systemic lupus erythematosus Dermatologic 1.05 0.693 – 1.53 0.827 36 139 exclusion phecode
695.7 Prurigo and Lichen Dermatologic 0.935 0.53 – 1.57 0.805 24 105 exclusion phecode
695.8 Other specified erythematous conditions Dermatologic 1.14 0.837 – 1.5 0.398 49 177 exclusion phecode
695.81 Erythema nodosum Dermatologic 1.53 0.612 – 4.57 0.389 4 24 exclusion phecode
695.9 Unspecified erythematous condition Dermatologic 1.1 0.746 – 1.56 0.61 32 125 exclusion phecode
696 Psoriasis and related disorders Dermatologic 1.18 0.927 – 1.49 0.176 60 303 exclusion phecode
696.3 Pityriasis Dermatologic 1.02 0.259 – 3.6 0.975 5 19 exclusion phecode
696.4 Psoriasis Dermatologic 1.18 0.913 – 1.5 0.206 54 275 exclusion phecode
696.41 Psoriasis vulgaris Dermatologic 1.2 0.925 – 1.55 0.169 51 250 exclusion phecode
696.42 Psoriatic arthropathy Dermatologic 0.74 0.139 – 2.47 0.618 6 64 exclusion phecode
697 Sarcoidosis Dermatologic 0.744 0.299 – 1.56 0.437 13 60 exclusion phecode
698 Pruritus and related conditions Dermatologic 1.06 0.901 – 1.24 0.476 179 703 exclusion phecode
700 Corns and callosities Dermatologic 1.04 0.798 – 1.33 0.776 86 214 exclusion phecode
701
Other hypertrophic and atrophic conditions of
Other hypertrophic and atrophic conditions of skin
 Dermatologic 1.07 0.951 – 1.2 0.257 433 787 exclusion phecode
701.1 Keratoderma, acquired Dermatologic 0.999 0.631 – 1.52 0.998 31 113 exclusion phecode
701.2 Scar conditions and fibrosis of skin Dermatologic 1.06 0.849 – 1.32 0.581 103 450 exclusion phecode
701.3 Circumscribed scleroderma Dermatologic 1.32 0.892 – 1.95 0.164 27 125 exclusion phecode
701.4 Keloid scar Dermatologic 0.795 0.496 – 1.2 0.302 33 167 exclusion phecode
701.5 Abnormal granulation tissue Dermatologic 0.881 0.47 – 1.5 0.663 19 83 exclusion phecode
702
Degenerative skin conditions and other
Degenerative skin conditions and other dermatoses
 Dermatologic 1.08 0.933 – 1.26 0.291 315 512 exclusion phecode
702.1 Actinic keratosis Dermatologic 1.09 0.883 – 1.32 0.427 132 377 exclusion phecode
702.2 Seborrheic keratosis Dermatologic 1.03 0.88 – 1.19 0.733 270 625 exclusion phecode
702.4 Degenerative skin disorders Dermatologic 1.12 0.432 – 2.96 0.821 8 29 exclusion phecode
703 Diseases of nail, NOS Dermatologic 1.24 0.997 – 1.53 0.0551 102 336 exclusion phecode
703.1 Ingrowing nail Dermatologic 1.14 0.829 – 1.55 0.414 63 220 exclusion phecode
704 Diseases of hair and hair follicles Dermatologic 1.07 0.928 – 1.22 0.351 248 758 exclusion phecode
704.1 Alopecia Dermatologic 0.989 0.819 – 1.18 0.904 143 459 exclusion phecode
704.11 Alopecia Areata Dermatologic 1.23 0.448 – 4.93 0.691 4 27 exclusion phecode
704.12 Telogen effluvium Dermatologic 1.24 0.602 – 2.39 0.501 5 24 exclusion phecode
704.2 Hirsutism Dermatologic 0.948 0.689 – 1.26 0.732 55 144 exclusion phecode
704.8
Other specified diseases of hair and hair
Other specified diseases of hair and hair follicles
 Dermatologic 1.09 0.901 – 1.31 0.356 115 430 exclusion phecode
705 Disorders of sweat glands Dermatologic 1.27 0.946 – 1.68 0.111 49 214 exclusion phecode
705.1 Dyshidrosis Dermatologic 1.08 0.578 – 1.96 0.805 13 38 exclusion phecode
705.3 Hidradenitis Dermatologic 1.22 0.761 – 1.9 0.397 17 107 exclusion phecode
705.8 Hyperhidrosis Dermatologic 1.13 0.881 – 1.43 0.326 83 273 exclusion phecode
706 Diseases of sebaceous glands Dermatologic 1.11 0.987 – 1.25 0.082 405 799 exclusion phecode
706.1 Acne Dermatologic 1.12 0.964 – 1.3 0.138 243 637 exclusion phecode
706.2 Sebaceous cyst Dermatologic 1.14 0.959 – 1.35 0.134 154 545 exclusion phecode
706.3 Seborrhea Dermatologic 1.3 0.501 – 3.57 0.664 8 13 exclusion phecode
706.8 Other specified diseases of sebaceous glands Dermatologic 1.24 0.995 – 1.56 0.0614 92 275 exclusion phecode
707 Chronic ulcer of skin Dermatologic 1.03 0.816 – 1.27 0.81 87 599 exclusion phecode
707.1 Decubitus ulcer Dermatologic 0.935 0.562 – 1.42 0.771 22 153 exclusion phecode
707.2 Chronic ulcer of leg or foot Dermatologic 1.16 0.802 – 1.6 0.395 35 189 exclusion phecode
707.3 Chronic ulcer of unspecified site Dermatologic 0.999 0.736 – 1.32 0.993 58 404 exclusion phecode
709 Diffuse diseases of connective tissue Dermatologic 0.922 0.702 – 1.18 0.535 81 344 exclusion phecode
709.2 Sicca syndrome Dermatologic 1.28 0.806 – 2.03 0.295 27 109 exclusion phecode
709.3 Systemic sclerosis Dermatologic 0.918 0.482 – 1.58 0.78 12 51 exclusion phecode
709.5 Dermatomyositis Dermatologic 0.992 0.308 – 12.1 0.987 4 21 exclusion phecode
709.6
Other specified diffuse diseases of connective
Other specified diffuse diseases of connective tissue
 Dermatologic 1.2 0.416 – 2.76 0.688 5 22 exclusion phecode
709.7 Unspecified diffuse connective tissue disease Dermatologic 0.801 0.57 – 1.08 0.168 59 242 exclusion phecode
710
Osteomyelitis, periostitis, and other
Osteomyelitis, periostitis, and other infections involving bone
 Musculoskeletal 0.827 0.545 – 1.19 0.331 34 212 exclusion phecode
710.1 Osteomyelitis Musculoskeletal 0.729 0.455 – 1.09 0.148 32 204 exclusion phecode
710.11 Acute osteomyelitis Musculoskeletal 0.558 0.223 – 1.18 0.146 15 97 exclusion phecode
710.12 Chronic osteomyelitis Musculoskeletal 0.488 0.176 – 1.05 0.0943 16 79 exclusion phecode
710.19 Unspecified osteomyelitis Musculoskeletal 0.769 0.478 – 1.16 0.236 29 202 exclusion phecode
711 Arthropathy associated with infections Musculoskeletal 0.927 0.504 – 1.65 0.807 16 56 exclusion phecode
711.1 Pyogenic arthritis Musculoskeletal 0.824 0.375 – 1.65 0.62 10 33 exclusion phecode
712 Infective connective tissue disorders Musculoskeletal 0.704 0.243 – 1.66 0.46 8 35 exclusion phecode
713
Arthropathy associated with other disorders
Arthropathy associated with other disorders classified elsewhere
 Musculoskeletal 1.11 0.758 – 1.58 0.575 19 79 exclusion phecode
713.5
Arthropathy associated with neurological
Arthropathy associated with neurological disorders
 Musculoskeletal 1.49 0.965 – 2.53 0.116 9 37 exclusion phecode
714
Rheumatoid arthritis and other inflammatory
Rheumatoid arthritis and other inflammatory polyarthropathies
 Musculoskeletal 0.568 0.398 – 0.779 0.000753 75 456 exclusion phecode
714.1 Rheumatoid arthritis Musculoskeletal 0.541 0.35 – 0.791 0.00233 54 359 exclusion phecode
714.2 Juvenile rheumatoid arthritis Musculoskeletal 0.377 0.0515 – 1.32 0.177 4 31 exclusion phecode
715 Other inflammatory spondylopathies Musculoskeletal 0.912 0.678 – 1.19 0.52 59 214 exclusion phecode
715.1 Sacroiliitis NEC Musculoskeletal 0.912 0.469 – 1.66 0.778 12 52 exclusion phecode
715.2 Ankylosing spondylitis Musculoskeletal 0.58 0.241 – 1.12 0.151 11 42 exclusion phecode
716 Other arthropathies Musculoskeletal 0.916 0.801 – 1.04 0.192 400 826 exclusion phecode
716.1 Unspecified polyarthropathy or polyarthritis Musculoskeletal 0.564 0.163 – 1.43 0.228 9 67 exclusion phecode
716.2 Unspecified monoarthritis Musculoskeletal 0.584 0.0535 – 3.14 0.46 7 23 exclusion phecode
716.9 Arthropathy NOS Musculoskeletal 0.917 0.803 – 1.04 0.199 399 826 exclusion phecode
717 Polymyalgia Rheumatica Musculoskeletal 1.11 0.28 – 3.58 0.87 5 37 exclusion phecode
720 Spinal stenosis Musculoskeletal 0.962 0.74 – 1.23 0.763 84 500 exclusion phecode
720.1 Spinal stenosis of lumbar region Musculoskeletal 1.03 0.742 – 1.39 0.863 55 332 exclusion phecode
721 Spondylosis and allied disorders Musculoskeletal 0.985 0.84 – 1.15 0.845 229 715 exclusion phecode
721.1 Spondylosis without myelopathy Musculoskeletal 0.977 0.83 – 1.14 0.775 220 693 exclusion phecode
721.2 Spondylosis with myelopathy Musculoskeletal 1.14 0.595 – 1.94 0.626 17 126 exclusion phecode
721.8 Other allied disorders of spine Musculoskeletal 0.851 0.462 – 1.32 0.542 14 49 exclusion phecode
722 Intervertebral disc disorders Musculoskeletal 1.03 0.88 – 1.19 0.727 231 793 exclusion phecode
722.1 Displacement of intervertebral disc Musculoskeletal 1.1 0.919 – 1.3 0.288 142 677 exclusion phecode
722.3 Schmorl's nodes Musculoskeletal 1.1 0.311 – 4.12 0.895 10 17 exclusion phecode
722.6 Degeneration of intervertebral disc Musculoskeletal 1.08 0.9 – 1.29 0.382 147 620 exclusion phecode
722.7 Intervertebral disc disorder with myelopathy Musculoskeletal 1.2 0.586 – 2.22 0.582 12 90 exclusion phecode
722.8 Postlaminectomy syndrome Musculoskeletal 0.632 0.264 – 1.34 0.23 12 76 exclusion phecode
722.9 Other and unspecified disc disorder Musculoskeletal 1.08 0.864 – 1.33 0.474 89 414 exclusion phecode
723 Other disorders of cervical region Musculoskeletal 1.04 0.764 – 1.38 0.81 55 242 exclusion phecode
723.1 Torticollis Musculoskeletal 1.28 0.665 – 2.49 0.457 8 64 exclusion phecode
724 Other and unspecified disorders of back Musculoskeletal 1.03 0.882 – 1.19 0.73 222 779 exclusion phecode
724.1 Disorders of sacrum Musculoskeletal 0.97 0.802 – 1.16 0.748 151 573 exclusion phecode
724.2 Disorders of coccyx Musculoskeletal 0.979 0.628 – 1.47 0.919 34 138 exclusion phecode
724.8 Other symptoms referable to back Musculoskeletal 1.05 0.773 – 1.38 0.745 52 226 exclusion phecode
724.9 Other unspecified back disorders Musculoskeletal 1.04 0.751 – 1.38 0.818 47 266 exclusion phecode
726 Peripheral enthesopathies and allied syndromes Musculoskeletal 1.02 0.892 – 1.17 0.775 493 519 exclusion phecode
726.1 Enthesopathy Musculoskeletal 1.05 0.908 – 1.21 0.525 388 518 exclusion phecode
726.2 Synoviopathy Musculoskeletal 1.08 0.759 – 1.52 0.659 59 123 exclusion phecode
726.3 Bursitis Musculoskeletal 0.868 0.658 – 1.13 0.31 114 248 exclusion phecode
726.4 Calcaneal spur; Exostosis NOS Musculoskeletal 0.843 0.571 – 1.19 0.359 59 190 exclusion phecode
727 Other disorders of synovium, tendon, and bursa Musculoskeletal 1.1 0.952 – 1.27 0.2 362 517 exclusion phecode
727.1 Synovitis and tenosynovitis Musculoskeletal 1.15 0.957 – 1.37 0.139 176 457 exclusion phecode
727.2 Bursitis disorders Musculoskeletal 1.31 0.817 – 2.16 0.294 21 55 exclusion phecode
727.4 Ganglion and cyst of synovium, tendon, and bursa Musculoskeletal 1.04 0.794 – 1.34 0.777 93 219 exclusion phecode
727.5 Rupture of synovium Musculoskeletal 0.845 0.426 – 1.54 0.605 18 58 exclusion phecode
727.6 Rupture of tendon, nontraumatic Musculoskeletal 1.01 0.776 – 1.29 0.943 98 220 exclusion phecode
727.7 Contracture of tendon (sheath) Musculoskeletal 1.38 0.903 – 2.12 0.149 41 111 exclusion phecode
727.8 Plica syndrome Musculoskeletal 1.2 0.0618 – 9.99 0.806 7 29 exclusion phecode
728 Disorders of muscle, ligament, and fascia Musculoskeletal 1.09 0.923 – 1.29 0.304 198 507 exclusion phecode
728.1 Muscular calcification and ossification Musculoskeletal 1.33 0.0842 – 16.4 0.792 8 9 exclusion phecode
728.2 Laxity of ligament or hypermobility syndrome Musculoskeletal 0.724 0.322 – 1.44 0.398 17 58 exclusion phecode
728.7 Fasciitis Musculoskeletal 0.97 0.798 – 1.17 0.762 200 382 exclusion phecode
728.71
Contracture of palmar fascia [Dupuytren's
Contracture of palmar fascia [Dupuytren's disease]
 Musculoskeletal 0.798 0.218 – 2.36 0.707 6 33 exclusion phecode
729 Other disorders of soft tissues Musculoskeletal 1.07 0.894 – 1.26 0.477 196 445 exclusion phecode
729.1 Rheumatism, unspecified and fibrositis Musculoskeletal 0.578 0.11 – 2.06 0.496 5 14 exclusion phecode
729.3 Panniculitis Musculoskeletal 1.11 0.237 – 11 0.894 4 14 exclusion phecode
729.7 Nontraumatic compartment syndrome Musculoskeletal 1.64 0.173 – 94.4 0.734 5 7 exclusion phecode
731
Osteitis deformans and osteopathies associated
Osteitis deformans and osteopathies associated with other disorders classified elsewhere
 Musculoskeletal 3.36 0.13 – 4940 0.223 4 33 exclusion phecode
732 Osteochondropathies Musculoskeletal 0.822 0.336 – 1.71 0.613 12 91 exclusion phecode
732.1 Juvenile osteochondrosis Musculoskeletal 0.813 0.318 – 1.74 0.627 11 40 exclusion phecode
732.7 Osteochondritis dissecans Musculoskeletal – 0 34 exclusion phecode
733 Other disorders of bone and cartilage Musculoskeletal 0.989 0.822 – 1.18 0.907 193 636 exclusion phecode
733.2 Cyst of bone Musculoskeletal 1.61 0.365 – 6.33 0.358 4 49 exclusion phecode
733.4 Aseptic necrosis of bone Musculoskeletal 0.914 0.483 – 1.56 0.759 15 74 exclusion phecode
733.6 Costochondritis Musculoskeletal 0.82 0.488 – 1.32 0.44 33 101 exclusion phecode
733.8 Malunion and nonunion of fracture Musculoskeletal 1.2 0.83 – 1.66 0.313 28 161 exclusion phecode
733.9 Chondromalacia Musculoskeletal 0.55 0.0588 – 1.65 0.377 4 22 exclusion phecode
735 Acquired foot deformities Musculoskeletal 1.04 0.876 – 1.22 0.664 165 688 exclusion phecode
735.1 Flat foot Musculoskeletal 1.26 0.881 – 1.79 0.213 41 135 exclusion phecode
735.2 Acquired toe deformities Musculoskeletal 1.17 0.877 – 1.55 0.275 65 247 exclusion phecode
735.21 Hammer toe (acquired) Musculoskeletal 0.962 0.62 – 1.41 0.855 31 148 exclusion phecode
735.23 Hallux rigidus Musculoskeletal 1.35 0.812 – 2.32 0.263 27 81 exclusion phecode
735.3 Hallux valgus (Bunion) Musculoskeletal 0.915 0.697 – 1.18 0.506 87 384 exclusion phecode
736 Other acquired deformities of limbs Musculoskeletal 1.03 0.852 – 1.23 0.764 128 597 exclusion phecode
736.1 Acquired deformities of forearm Musculoskeletal 1.46 0.23 – 22.3 0.679 2 15 exclusion phecode
736.2 Acquired deformities of finger Musculoskeletal 1.24 0.487 – 2.96 0.622 6 54 exclusion phecode
736.3 Acquired deformities of hip Musculoskeletal 0.924 0.111 – 9.93 0.891 3 27 exclusion phecode
736.4 Genu valgum or varum (acquired) Musculoskeletal 0.856 0.413 – 1.57 0.644 11 53 exclusion phecode
736.5 Acquired deformities of knee Musculoskeletal 0.973 0.35 – 2.16 0.95 8 40 exclusion phecode
736.6 Unequal leg length (acquired) Musculoskeletal 1.16 0.652 – 1.99 0.6 14 79 exclusion phecode
737 Curvature of spine Musculoskeletal 0.807 0.591 – 1.07 0.149 69 342 exclusion phecode
737.1 Kyphosis (acquired) Musculoskeletal 0.689 0.331 – 1.26 0.253 14 99 exclusion phecode
737.2 Lordosis (acquired) Musculoskeletal 0.591 0.0117 – 4.42 0.575 2 17 exclusion phecode
737.3 Kyphoscoliosis and scoliosis Musculoskeletal 0.923 0.654 – 1.26 0.627 54 266 exclusion phecode
738 Other acquired musculoskeletal deformity Musculoskeletal 0.761 0.549 – 1.02 0.0743 72 508 exclusion phecode
738.4 Acquired spondylolisthesis Musculoskeletal 0.886 0.571 – 1.3 0.561 34 164 exclusion phecode
739 Contracture of joint Musculoskeletal 0.951 0.549 – 1.55 0.846 20 136 exclusion phecode
740 Osteoarthrosis Musculoskeletal 1.05 0.928 – 1.19 0.424 468 796 exclusion phecode
740.1 Osteoarthritis; localized Musculoskeletal 1.11 0.945 – 1.29 0.209 252 663 exclusion phecode
740.11 Osteoarthrosis, localized, primary Musculoskeletal 1.11 0.939 – 1.3 0.219 223 602 exclusion phecode
740.12 Osteoarthrosis, localized, secondary Musculoskeletal 1.17 0.761 – 1.78 0.466 25 109 exclusion phecode
740.2 Osteoarthrosis, generalized Musculoskeletal 0.849 0.588 – 1.2 0.373 57 181 exclusion phecode
740.3
Osteoarthrosis involving more than one site
Osteoarthrosis involving more than one site, but not specified as generalized
 Musculoskeletal 1.05 0.512 – 2.06 0.889 14 47 exclusion phecode
740.9 Osteoarthrosis NOS Musculoskeletal 1.03 0.902 – 1.17 0.666 448 796 exclusion phecode
741 Symptoms and disorders of the joints Musculoskeletal 1.04 0.914 – 1.18 0.549 349 809 exclusion phecode
741.1 Ankylosis of joint Musculoskeletal 1.23 0.509 – 2.87 0.631 6 57 exclusion phecode
741.2 Stiffness of joint Musculoskeletal 1.13 0.843 – 1.49 0.411 64 295 exclusion phecode
741.3 Difficulty in walking Musculoskeletal 1.27 0.982 – 1.62 0.0611 71 346 exclusion phecode
741.4 Joint effusions Musculoskeletal 0.949 0.769 – 1.16 0.616 129 542 exclusion phecode
741.5 Hemarthrosis Musculoskeletal 0.977 0.262 – 6.29 0.975 8 14 exclusion phecode
741.6 Villonodular synovitis Musculoskeletal 0.692 0.0387 – 3.67 0.671 2 27 exclusion phecode
742 Derangement of joint, non-traumatic Musculoskeletal 0.927 0.786 – 1.08 0.354 235 794 exclusion phecode
742.1 Loose body in joint Musculoskeletal 0.647 0.123 – 1.63 0.401 6 37 exclusion phecode
742.2
Pathological, developmental or recurrent
Pathological, developmental or recurrent dislocation
 Musculoskeletal 0.85 0.348 – 1.74 0.669 10 67 exclusion phecode
742.8 Articular cartilage disorder Musculoskeletal 0.476 0.156 – 1.14 0.116 15 70 exclusion phecode
742.9 Other derangement of joint Musculoskeletal 0.959 0.812 – 1.13 0.618 222 786 exclusion phecode
743
Osteoporosis, osteopenia and pathological
Osteoporosis, osteopenia and pathological fracture
 Musculoskeletal 0.965 0.842 – 1.1 0.602 368 880 exclusion phecode
743.1 Osteoporosis Musculoskeletal 0.902 0.724 – 1.11 0.345 141 378 exclusion phecode
743.11 Osteoporosis NOS Musculoskeletal 0.901 0.722 – 1.11 0.338 140 376 exclusion phecode
743.12 Senile osteoporosis Musculoskeletal 0.93 0.57 – 1.48 0.771 34 55 exclusion phecode
743.13 Other specified osteoporosis Musculoskeletal 0.555 0.251 – 0.963 0.0714 21 40 exclusion phecode
743.2 Pathologic fracture Musculoskeletal 0.819 0.554 – 1.15 0.287 47 150 exclusion phecode
743.21 Pathologic fracture of vertebrae Musculoskeletal 0.697 0.286 – 1.45 0.366 17 63 exclusion phecode
743.22 Pathologic fracture of femur Musculoskeletal 1.07 0.369 – 3.03 0.905 9 19 exclusion phecode
743.4 Stress fracture Musculoskeletal 0.764 0.466 – 1.13 0.216 38 130 exclusion phecode
743.9
Osteopenia or other disorder of bone and
Osteopenia or other disorder of bone and cartilage
 Musculoskeletal 0.97 0.837 – 1.12 0.683 300 816 exclusion phecode
745 Pain in joint Musculoskeletal 0.935 0.83 – 1.05 0.266 823 446 exclusion phecode
747 Cardiac and circulatory congenital anomalies Congenital Anomalies 0.962 0.753 – 1.2 0.743 87 573 exclusion phecode
747.1 Cardiac congenital anomalies Congenital Anomalies 1.02 0.778 – 1.3 0.874 63 425 exclusion phecode
747.11 Cardiac shunt/ heart septal defect Congenital Anomalies 0.883 0.546 – 1.33 0.568 26 203 exclusion phecode
747.12 Valvular heart disease/ heart chambers Congenital Anomalies 0.782 0.455 – 1.25 0.326 23 133 exclusion phecode
747.13 Congenital anomalies of great vessels Congenital Anomalies 1.3 0.661 – 2.49 0.441 14 76 exclusion phecode
747.2
Congenital anomalies of peripheral vascular
Congenital anomalies of peripheral vascular system
 Congenital Anomalies 0.983 0.585 – 1.56 0.943 27 162 exclusion phecode
748 Anomalies of respiratory system, congenital Congenital Anomalies 1.61 0.487 – 6.56 0.442 4 37 exclusion phecode
749 Congenital anomalies of face and neck Congenital Anomalies 0.872 0.531 – 1.35 0.56 28 145 exclusion phecode
749.1 Cleft palate Congenital Anomalies 0.815 0.137 – 3.24 0.784 3 22 exclusion phecode
749.2 Congenital anomalies of skull and face bones Congenital Anomalies 0.817 3.03e-05 – 3.94 0.786 3 31 exclusion phecode
750 Digestive congenital anomalies Congenital Anomalies 1.18 0.879 – 1.57 0.271 46 235 exclusion phecode
750.1 Upper gastrointestinal congenital anomalies Congenital Anomalies 1.31 0.851 – 2.07 0.246 12 79 exclusion phecode
750.11 Esophageal atresia/tracheoesophageal fistula Congenital Anomalies 0.418 0.00108 – 3.51 0.491 4 23 exclusion phecode
750.13 Congenital anomalies of mouth/tongue Congenital Anomalies 3.47 1.23 – 34.8 0.0557 4 24 exclusion phecode
750.14 Congenital anomalies of esophagus Congenital Anomalies 1.3 0.405 – 4.17 0.68 4 18 exclusion phecode
750.15 Congenital anomalies of stomach Congenital Anomalies 2.09 0.712 – 79 0.34 2 17 exclusion phecode
750.2 Lower gastrointestinal congenital anomalies Congenital Anomalies 0.884 0.581 – 1.24 0.516 32 156 exclusion phecode
750.21 Congenital anomalies of intestine Congenital Anomalies 0.983 0.472 – 1.98 0.962 15 88 exclusion phecode
750.22
Congenital anomaly of gallbladder, bile ducts
Congenital anomaly of gallbladder, bile ducts, liver, pancreas
 Congenital Anomalies 0.758 0.392 – 1.19 0.298 18 70 exclusion phecode
751 Genitourinary congenital anomalies Congenital Anomalies 1.11 0.906 – 1.34 0.309 111 530 exclusion phecode
751.1 Congenital anomalies of genital organs Congenital Anomalies 1.19 0.894 – 1.57 0.233 65 225 exclusion phecode
751.11 Congenital anomalies of female genital organs Congenital Anomalies 1.27 0.95 – 1.7 0.108 58 202 exclusion phecode
751.12 Congenital anomalies of male genital organs Congenital Anomalies 0.182 0.000367 – 0.822 0.0725 7 20 exclusion phecode
751.2 Congenital anomalies of urinary system Congenital Anomalies 1.02 0.746 – 1.35 0.881 50 308 exclusion phecode
751.21 Cystic kidney disease Congenital Anomalies 1.02 0.699 – 1.39 0.926 35 205 exclusion phecode
751.22 Other specified congenital anomalies of kidney Congenital Anomalies 1.51 0.793 – 2.98 0.206 8 70 exclusion phecode
751.3 Obstructive genitourinary defect Congenital Anomalies 3.99 1.45 – 43.4 0.0282 6 45 exclusion phecode
752 Nervous system congenital anomalies Congenital Anomalies 0.978 0.675 – 1.35 0.898 43 263 exclusion phecode
752.1 Neural tube defects Congenital Anomalies 1.03 0.673 – 1.47 0.866 31 181 exclusion phecode
752.11 Spina bifida Congenital Anomalies 1.11 0.711 – 1.8 0.664 8 51 exclusion phecode
752.2
Other specified congenital anomalies of nervous
Other specified congenital anomalies of nervous system
 Congenital Anomalies 0.92 0.412 – 1.86 0.818 10 85 exclusion phecode
753 Congenital anomalies of the eye Congenital Anomalies 0.77 0.335 – 1.45 0.466 13 61 exclusion phecode
753.1 Congenital cataract and lens anomalies Congenital Anomalies 1.71 0.103 – 41500 0.719 4 12 exclusion phecode
753.2 Congenital anomalies of posterior segment of eye Congenital Anomalies 0.828 0.0439 – 3.33 0.801 4 11 exclusion phecode
754 Congenital musculoskeletal deformities of spine Congenital Anomalies 1.09 0.789 – 1.48 0.601 50 224 exclusion phecode
754.1 Lumbosacral spondylolysis, congenital Congenital Anomalies 1.37 0.542 – 3.71 0.539 10 33 exclusion phecode
754.2 Spondylolisthesis, congenital Congenital Anomalies 0.994 0.598 – 1.62 0.982 23 94 exclusion phecode
755 Congenital anomalies of limbs Congenital Anomalies 1.09 0.769 – 1.48 0.617 44 235 exclusion phecode
755.1 Congenital deformities of feet Congenital Anomalies 1.36 0.912 – 2.02 0.144 24 112 exclusion phecode
755.4
Congenital anomalies of upper limb, including
Congenital anomalies of upper limb, including shoulder girdle
 Congenital Anomalies 0.629 0.000165 – 36.1 0.687 5 14 exclusion phecode
755.6
Other congenital anomalies of lower limb
Other congenital anomalies of lower limb, including pelvic girdle
 Congenital Anomalies 0.747 0.407 – 1.24 0.293 19 104 exclusion phecode
755.61 Congenital hip dysplasia and deformity Congenital Anomalies 0.776 0.365 – 1.49 0.466 10 86 exclusion phecode
756 Other congenital musculoskeletal anomalies Congenital Anomalies 0.962 0.709 – 1.28 0.796 63 374 exclusion phecode
756.1 Congenital anomalies of abdominal wall; diaphram Congenital Anomalies 0.639 0.0698 – 1.95 0.484 5 33 exclusion phecode
756.2
Pectus and other congenital anomalies of
Pectus and other congenital anomalies of ribs/sternum
 Congenital Anomalies 2.47 0.236 – 491 0.503 3 19 exclusion phecode
756.3
Congenital anomalies of muscle, tendon, fascia
Congenital anomalies of muscle, tendon, fascia, and connective tissue
 Congenital Anomalies 0.624 0.225 – 1.3 0.238 13 95 exclusion phecode
756.5 Congenital osteodystrophies Congenital Anomalies 0.96 0.662 – 1.34 0.817 42 249 exclusion phecode
757 Congenital anomalies of the integument Congenital Anomalies 1.4 0.843 – 2.29 0.195 18 99 exclusion phecode
758 Chromosomal anomalies and genetic disorders Congenital Anomalies 0.845 0.468 – 1.4 0.544 18 74 exclusion phecode
758.1 Chromosomal anomalies Congenital Anomalies 0.897 0.436 – 1.69 0.752 18 61 exclusion phecode
759 Other and unspecified congenital anomalies Congenital Anomalies 0.783 0.501 – 1.17 0.255 40 206 exclusion phecode
759.1 Anomalies of endocrine glands, congenital Congenital Anomalies 0.598 0.171 – 1.46 0.345 6 26 exclusion phecode
760 Back pain Symptoms 1.04 0.927 – 1.17 0.516 734 535 exclusion phecode
761 Cervicalgia Symptoms 1.02 0.9 – 1.15 0.764 373 891 exclusion phecode
763
Thoracic or lumbosacral neuritis or
Thoracic or lumbosacral neuritis or radiculitis, unspecified
 Symptoms 1.05 0.872 – 1.24 0.614 144 680 exclusion phecode
764 Sciatica Symptoms 0.969 0.805 – 1.15 0.732 155 749 exclusion phecode
765 Cervical radiculitis Symptoms 1.03 0.821 – 1.28 0.791 106 380 exclusion phecode
766 Neuralgia, neuritis, and radiculitis NOS Symptoms 0.992 0.848 – 1.15 0.923 218 884 exclusion phecode
767 Cervicocranial/Cervicobrachial syndrome Symptoms 1.87 0.759 – 5.29 0.213 18 30 exclusion phecode
769 Nonallopathic lesions NEC Symptoms 0.879 0.681 – 1.11 0.296 90 311 exclusion phecode
770 Myalgia and myositis unspecified Symptoms 0.943 0.828 – 1.07 0.368 358 848 exclusion phecode
771 Musculoskeletal symptoms referable to limbs Symptoms 0.929 0.779 – 1.1 0.397 193 820 exclusion phecode
771.1 Swelling of limb Symptoms 1.04 0.9 – 1.19 0.61 269 807 exclusion phecode
771.2 Cramp of limb Symptoms 1.2 0.875 – 1.63 0.251 61 225 exclusion phecode
772 Symptoms of the muscles Symptoms 0.954 0.786 – 1.14 0.621 147 509 exclusion phecode
772.1 Muscular wasting and disuse atrophy Symptoms 0.952 0.409 – 1.95 0.898 10 91 exclusion phecode
772.2 Spasm of muscle Symptoms 1.19 1.01 – 1.39 0.0361 156 662 exclusion phecode
772.3 Muscle weakness Symptoms 1.03 0.799 – 1.31 0.786 85 527 exclusion phecode
772.4 Rhabdomyolysis Symptoms 1.54 0.574 – 12.9 0.443 7 23 exclusion phecode
772.6 Facial weakness Symptoms 1.36 0.676 – 2.69 0.357 16 97 exclusion phecode
780 Hypothermia/Chills Symptoms 0.93 0.593 – 1.38 0.733 29 131 exclusion phecode
781
Symptoms involving nervous and musculoskeletal
Symptoms involving nervous and musculoskeletal systems
 Symptoms 0.993 0.796 – 1.22 0.951 100 581 exclusion phecode
781.1 Loss of height Symptoms 0.879 0.0143 – 8.45 0.907 1 21 exclusion phecode
781.2 Abnormal posture Symptoms 1.78 0.135 – 8.05 0.513 2 14 exclusion phecode
782.3 Edema Symptoms 0.982 0.851 – 1.13 0.795 262 843 exclusion phecode
782.6 Pallor and flushing Symptoms 0.99 0.786 – 1.22 0.928 93 323 exclusion phecode
783 Fever of unknown origin Symptoms 1 0.875 – 1.14 0.964 273 992 exclusion phecode
783.1 Postprocedural fever Symptoms 1.51 0.903 – 2.58 0.129 11 77 exclusion phecode
785 Abdominal pain Symptoms 0.95 0.847 – 1.07 0.382 830 439 exclusion phecode
788 Syncope and collapse Symptoms 1.05 0.891 – 1.22 0.575 186 911 exclusion phecode
789 Nausea and vomiting Symptoms 0.973 0.867 – 1.09 0.647 486 782 exclusion phecode
789.1 Persistent vomiting Symptoms 0.931 0.627 – 1.32 0.697 37 250 exclusion phecode
790 Nonspecific findings on examination of blood Symptoms 0.915 0.72 – 1.14 0.454 109 420 exclusion phecode
790.1 Elevated sedimentation rate Symptoms 1.21 0.805 – 1.97 0.412 12 67 exclusion phecode
790.6 Other abnormal blood chemistry Symptoms 0.957 0.841 – 1.09 0.502 378 844 exclusion phecode
790.8 Elevated C-reactive protein (CRP) Symptoms 2.13 1.13 – 4.15 0.0227 17 89 exclusion phecode
790.9 Abnormal arterial blood gases Symptoms 1.68 0.331 – 19.3 0.597 6 21 exclusion phecode
791 Gangrene Symptoms 0.924 0.333 – 2.02 0.854 5 60 exclusion phecode
792
Abnormal Papanicolaou smear of cervix and
Abnormal Papanicolaou smear of cervix and cervical HPV
 Genitourinary 1.04 0.883 – 1.23 0.636 261 369 exclusion phecode
792.1
Papanicolaou smear of cervix or vagina with
Papanicolaou smear of cervix or vagina with atypical squamous cells
 Genitourinary 1.02 0.8 – 1.29 0.868 112 295 exclusion phecode
794
Abnormal results of other function studies
Abnormal results of other function studies (bladder, pancreas, placenta, spleen, etc)
 Symptoms 1.19 0.572 – 2.24 0.6 12 108 exclusion phecode
795
Other and nonspecific abnormal cytological
Other and nonspecific abnormal cytological, histological and immunological findings
 Symptoms 0.975 0.814 – 1.16 0.778 161 801 exclusion phecode
795.8 Abnormal tumor markers Symptoms 0.999 0.679 – 1.43 0.994 45 175 exclusion phecode
795.81 Elevated carcinoembryonic antigen [CEA] Symptoms 0.405 0.00615 – 0.374 0.998 1 8 exclusion phecode
795.82 Elevated cancer antigen 125 [CA 125] Symptoms 0.629 0.156 – 1.95 0.435 8 47 exclusion phecode
796 Elevated prostate specific antigen [PSA] Genitourinary 0.98 0.633 – 1.48 0.928 41 64 exclusion phecode
797 Shock Symptoms 0.87 0.39 – 1.58 0.661 11 96 exclusion phecode
797.1 Cardiogenic shock Symptoms 0.72 0.0969 – 1.85 0.543 2 37 exclusion phecode
798 Malaise and fatigue Symptoms 0.935 0.835 – 1.05 0.249 686 583 exclusion phecode
798.1 Chronic fatigue syndrome Symptoms 0.84 0.672 – 1.03 0.114 138 347 exclusion phecode
800 Fracture of lower limb Injuries & Poisonings 1.08 0.865 – 1.33 0.477 92 514 exclusion phecode
800.1 Fracture of neck of femur Injuries & Poisonings 0.95 0.536 – 1.54 0.848 20 85 exclusion phecode
800.2 Fracture of unspecified part of femur Injuries & Poisonings 0.729 0.365 – 1.33 0.323 21 105 exclusion phecode
800.3 Fracture of tibia and fibula Injuries & Poisonings 1.28 0.906 – 1.8 0.158 35 189 exclusion phecode
800.4 Fracture of patella Injuries & Poisonings 0.942 0.514 – 1.55 0.827 17 83 exclusion phecode
801 Fracture of ankle and foot Injuries & Poisonings 1.09 0.906 – 1.3 0.337 125 626 exclusion phecode
801.1 Fracture of foot Injuries & Poisonings 1.1 0.831 – 1.41 0.493 53 290 exclusion phecode
802 Fracture of pelvis Injuries & Poisonings 0.607 0.223 – 1.25 0.202 10 78 exclusion phecode
803 Fracture of upper limb Injuries & Poisonings 1.01 0.783 – 1.28 0.919 81 487 exclusion phecode
803.1 Fracture of humerus Injuries & Poisonings 0.859 0.534 – 1.29 0.489 28 144 exclusion phecode
803.2 Fracture of radius and ulna Injuries & Poisonings 1.16 0.872 – 1.52 0.287 56 281 exclusion phecode
803.21 Colles' fracture Injuries & Poisonings 1.21 0.683 – 2.09 0.522 17 57 exclusion phecode
803.3 Fracture of clavicle or scapula Injuries & Poisonings 0.72 0.288 – 1.5 0.399 15 94 exclusion phecode
804 Fracture of hand or wrist Injuries & Poisonings 0.769 0.553 – 1.03 0.0921 74 395 exclusion phecode
805
Fracture of vertebral column without mention of
Fracture of vertebral column without mention of spinal cord injury
 Injuries & Poisonings 0.753 0.5 – 1.08 0.145 50 222 exclusion phecode
807 Fracture of ribs Injuries & Poisonings 0.926 0.546 – 1.46 0.757 24 103 exclusion phecode
809 Fracture of unspecified bones Injuries & Poisonings 0.966 0.776 – 1.18 0.742 111 718 exclusion phecode
816 Cerebral laceration and contusion Injuries & Poisonings 0.85 0.294 – 3.96 1 3 3 exclusion phecode
817 Concussion Injuries & Poisonings 1.07 0.797 – 1.4 0.651 57 315 exclusion phecode
818 Intracranial hemorrhage (injury) Injuries & Poisonings 1 0.275 – 1.99 0.993 5 49 exclusion phecode
818.1 Subdural hemorrhage (injury) Injuries & Poisonings 1.59 0.139 – 84.7 0.731 1 12 exclusion phecode
818.2 Subarachnoid hemorrhage (injury) Injuries & Poisonings 1.04 0.324 – 2.22 0.911 3 30 exclusion phecode
819
Skull and face fracture and other intercranial
Skull and face fracture and other intercranial injury
 Injuries & Poisonings 0.904 0.695 – 1.15 0.423 89 598 exclusion phecode
830 Dislocation Injuries & Poisonings 0.888 0.742 – 1.05 0.18 179 901 exclusion phecode
835 Internal derangement of knee Injuries & Poisonings 0.742 0.571 – 0.944 0.019 109 538 exclusion phecode
836 Traumatic arthropathy Injuries & Poisonings 0.457 0.171 – 0.923 0.051 16 72 exclusion phecode
840 Sprains and strains Injuries & Poisonings 0.978 0.864 – 1.1 0.724 421 798 exclusion phecode
840.1 Muscle/tendon sprain Injuries & Poisonings 1.07 0.654 – 1.72 0.79 28 61 exclusion phecode
840.2 Rotator cuff (capsule) sprain Injuries & Poisonings 0.95 0.713 – 1.23 0.713 74 216 exclusion phecode
840.3 Joint/ligament sprain Injuries & Poisonings 1.05 0.876 – 1.26 0.573 142 650 exclusion phecode
841 Sprains and strains of back and neck Injuries & Poisonings 0.953 0.756 – 1.19 0.674 109 403 exclusion phecode
842 Other sprains and strains Injuries & Poisonings 1.01 0.767 – 1.31 0.943 78 342 exclusion phecode
850 Hemorrhage or hematoma complicating a procedure Injuries & Poisonings 0.936 0.695 – 1.22 0.638 60 499 exclusion phecode
851
Complications of transplants and reattached
Complications of transplants and reattached limbs
 Injuries & Poisonings 1.13 0.885 – 1.41 0.294 64 591 exclusion phecode
853 Complication of colostomy or enterostomy Injuries & Poisonings 1.43 0.753 – 2.65 0.251 12 102 exclusion phecode
854
Complications of cardiac/vascular device
Complications of cardiac/vascular device, implant, and graft
 Injuries & Poisonings 1.08 0.826 – 1.37 0.53 58 418 exclusion phecode
855
Complication of nervous system device, implant
Complication of nervous system device, implant, and graft
 Injuries & Poisonings 0.862 0.00167 – 3 0.814 2 69 exclusion phecode
856
Vascular complications of surgery and medical
Vascular complications of surgery and medical procedures
 Injuries & Poisonings 1.28 0.551 – 2.72 0.525 7 64 exclusion phecode
857
Mechanical complication of unspecified
Mechanical complication of unspecified genitourinary device, implant, and graft
 Injuries & Poisonings 1.08 0.832 – 1.37 0.539 65 410 exclusion phecode
858 Complication of internal orthopedic device Injuries & Poisonings 1.12 0.832 – 1.48 0.429 55 515 exclusion phecode
859
Complication due to other implant and internal
Complication due to other implant and internal device
 Injuries & Poisonings 1.11 0.845 – 1.43 0.422 64 558 exclusion phecode
860 Bone marrow or stem cell transplant Neoplasms 1.2 0.438 – 3.07 0.705 8 38 exclusion phecode
870 Open wounds of head; neck; and trunk Injuries & Poisonings 1.07 0.898 – 1.26 0.436 153 835 exclusion phecode
870.1 Open wound or laceration of eye or eyelid Injuries & Poisonings 0.716 0.158 – 2.07 0.558 7 45 exclusion phecode
870.2 Open wound of ear Injuries & Poisonings 0.51 0.0608 – 2.9 0.46 6 32 exclusion phecode
870.3 Other open wound of head and face Injuries & Poisonings 1.02 0.692 – 1.45 0.919 41 270 exclusion phecode
870.4 Open wound of nose and sinus Injuries & Poisonings 1.28 0.359 – 6.53 0.68 4 47 exclusion phecode
870.5 Open wound of lip and mouth Injuries & Poisonings 1.03 0.362 – 2.48 0.94 5 53 exclusion phecode
870.6 Open wound of neck Injuries & Poisonings 1.7 0.303 – 30.9 0.474 1 34 exclusion phecode
870.8 Open wound of genital organs Injuries & Poisonings 1.17 0.687 – 1.96 0.568 8 57 exclusion phecode
871 Open wounds of extremities Injuries & Poisonings 1.06 0.901 – 1.24 0.456 159 716 exclusion phecode
871.1 Open wound of hand except finger(s) Injuries & Poisonings 1.25 0.904 – 1.73 0.179 25 151 exclusion phecode
871.2 Open wound of finger(s) Injuries & Poisonings 1.04 0.754 – 1.4 0.817 55 238 exclusion phecode
871.3 Open wound of foot except toe(s) alone Injuries & Poisonings 1.1 0.638 – 1.83 0.712 23 104 exclusion phecode
871.4 Open wound of toe(s) Injuries & Poisonings 1.05 0.553 – 1.88 0.881 15 48 exclusion phecode
872 Traumatic amputation Injuries & Poisonings 0.574 0.141 – 1.48 0.263 5 70 exclusion phecode
874 Complication of amputation stump Injuries & Poisonings 1.88 0.0682 – 219 0.522 1 23 exclusion phecode
875 Non-healing surgical wound Injuries & Poisonings 1.03 0.484 – 2.01 0.927 12 133 exclusion phecode
876
Posttraumatic wound infection not elsewhere
Posttraumatic wound infection not elsewhere classified
 Injuries & Poisonings 1.3 0.942 – 1.82 0.126 28 175 exclusion phecode
907 Injuries to the nervous system Injuries & Poisonings 1.11 0.786 – 1.52 0.533 41 221 exclusion phecode
910 Superficial injury, infected Injuries & Poisonings 2.6 1.16 – 9.05 0.041 7 36 exclusion phecode
911 Blister Injuries & Poisonings 0.79 0.312 – 1.32 0.465 17 76 exclusion phecode
912 Insect bite Injuries & Poisonings 1.22 0.866 – 1.69 0.256 28 154 exclusion phecode
913 Toxic effect of venom Injuries & Poisonings 0.889 0.502 – 1.47 0.653 13 98 exclusion phecode
916 Contusion Injuries & Poisonings 1.08 0.933 – 1.24 0.302 230 945 exclusion phecode
930 Allergic reaction to food Injuries & Poisonings 0.927 0.686 – 1.23 0.614 76 172 exclusion phecode
931
Contact dermatitis and other eczema due to
Contact dermatitis and other eczema due to plants [except food]
 Dermatologic 0.931 0.631 – 1.33 0.706 41 136 exclusion phecode
938 Dermatitis due to solar radiation Dermatologic 1.05 0.896 – 1.23 0.54 281 472 exclusion phecode
938.1 Acute dermatitis due to solar radiation Dermatologic 0.76 0.431 – 1.27 0.329 20 47 exclusion phecode
938.2 Chronic dermatitis due to solar radiation Dermatologic 1.06 0.895 – 1.24 0.52 269 461 exclusion phecode
939
Atopic/contact dermatitis due to other or
Atopic/contact dermatitis due to other or unspecified
 Dermatologic 0.998 0.87 – 1.14 0.975 435 537 exclusion phecode
939.1 Contact and allergic dermatitis of eyelid Dermatologic 1.06 0.501 – 2.33 0.881 13 24 exclusion phecode
941 Adverse reaction to serum or vaccine Injuries & Poisonings 0.79 0.398 – 1.39 0.47 8 36 exclusion phecode
942 Infusion and transfusion reaction Injuries & Poisonings 1.26 0.673 – 2.33 0.479 20 55 exclusion phecode
946 Anaphylactic shock NOS Injuries & Poisonings 0.653 0.387 – 1.02 0.0794 37 109 exclusion phecode
947 Urticaria Dermatologic 0.852 0.65 – 1.1 0.234 106 276 exclusion phecode
949 Allergies, other Injuries & Poisonings 1.06 0.935 – 1.21 0.35 425 536 exclusion phecode
952
Spinal cord injury without evidence of spinal
Spinal cord injury without evidence of spinal bone injury
 Injuries & Poisonings 0.653 0.277 – 1.25 0.242 15 86 exclusion phecode
957 Injury to other and unspecified nerves Injuries & Poisonings 1.89 0.62 – 12.5 0.221 5 42 exclusion phecode
958
Certain early complications of trauma or
Certain early complications of trauma or procedure
 Injuries & Poisonings 1.14 0.8 – 1.54 0.431 35 277 exclusion phecode
958.1 Postoperative shock Injuries & Poisonings 1.11 0.125 – 5.65 0.882 1 36 exclusion phecode
958.2 Traumatic and surgical subcutaneous emphysema Injuries & Poisonings 0.232 0.000842 – 1.82 0.234 3 24 exclusion phecode
960 Poisoning by antibiotics Injuries & Poisonings 0.846 0.656 – 1.07 0.173 92 541 exclusion phecode
960.1
Adverse effects of antibacterials (not
Adverse effects of antibacterials (not penicillins)
 Injuries & Poisonings 0.833 0.486 – 1.31 0.455 23 90 exclusion phecode
960.2 Allergy/adverse effect of penicillin Injuries & Poisonings 0.862 0.611 – 1.17 0.355 52 385 exclusion phecode
961 Poisoning by other anti-infectives Injuries & Poisonings 0.705 0.415 – 1.11 0.156 32 142 exclusion phecode
961.1 Poisoning/allergy of sulfonamides Injuries & Poisonings 1.31 0.94 – 1.79 0.0951 36 264 exclusion phecode
962 Poisoning by hormones and synthetic substitutes Injuries & Poisonings 1.04 0.683 – 1.51 0.845 32 183 exclusion phecode
962.1
Adrenal cortical steroids causing adverse
Adrenal cortical steroids causing adverse effects in therapeutic use
 Injuries & Poisonings 0.989 0.48 – 1.55 0.968 14 68 exclusion phecode
962.2
Insulins and antidiabetic agents causing
Insulins and antidiabetic agents causing adverse effects in therapeutic use
 Injuries & Poisonings 1.35 0.306 – 3.94 0.597 2 27 exclusion phecode
962.3
Hormones and synthetic substitutes causing
Hormones and synthetic substitutes causing adverse effects in therapeutic use
 Injuries & Poisonings 1.15 0.678 – 1.84 0.588 19 106 exclusion phecode
963 Poisoning by primarily systemic agents Injuries & Poisonings 1.06 0.856 – 1.29 0.575 103 543 exclusion phecode
963.1
Antineoplastic and immunosuppressive drugs
Antineoplastic and immunosuppressive drugs causing adverse effects
 Injuries & Poisonings 1.07 0.867 – 1.31 0.494 99 524 exclusion phecode
964
Poisoning by agents primarily affecting blood
Poisoning by agents primarily affecting blood constituents
 Injuries & Poisonings 1.02 0.635 – 1.56 0.944 26 133 exclusion phecode
964.1 Anticoagulants causing adverse effects Injuries & Poisonings 0.964 0.552 – 1.59 0.888 23 125 exclusion phecode
965
Poisoning by analgesics, antipyretics, and
Poisoning by analgesics, antipyretics, and antirheumatics
 Injuries & Poisonings 1.2 0.834 – 1.68 0.315 41 222 exclusion phecode
965.1
Opiates and related narcotics causing adverse
Opiates and related narcotics causing adverse effects in therapeutic use
 Injuries & Poisonings 0.955 0.692 – 1.28 0.766 58 362 exclusion phecode
965.3
Salicylates causing adverse effects in
Salicylates causing adverse effects in therapeutic use
 Injuries & Poisonings 0.861 0.294 – 1.79 0.734 7 26 exclusion phecode
966
Poisoning by anticonvulsants and
Poisoning by anticonvulsants and anti-Parkinsonism drugs
 Injuries & Poisonings 0.944 0.00487 – 2.13 0.889 2 27 exclusion phecode
967
Adverse effects of sedatives or other central
Adverse effects of sedatives or other central nervous system depressants and anesthetics
 Injuries & Poisonings 1.07 0.849 – 1.33 0.549 85 347 exclusion phecode
969 Poisoning by psychotropic agents Injuries & Poisonings 0.677 0.262 – 1.42 0.329 15 86 exclusion phecode
971
Poisoning by drugs primarily affecting the
Poisoning by drugs primarily affecting the autonomic nervous system
 Injuries & Poisonings 2.32 0.00123 – 224 0.76 1 10 exclusion phecode
972
Poisoning by agents primarily affecting the
Poisoning by agents primarily affecting the cardiovascular system
 Injuries & Poisonings 0.754 0.197 – 1.88 0.599 5 32 exclusion phecode
972.1
Cardiac rhythm regulators causing adverse
Cardiac rhythm regulators causing adverse effects in therapeutic use
 Injuries & Poisonings 1340 2.7e-08 – 2370 0.993 1 8 exclusion phecode
972.6 Antihypertensive agents causing adverse effects Injuries & Poisonings 1.78 0.303 – 43.8 0.589 1 16 exclusion phecode
974
Poisoning by water, mineral, and uric acid
Poisoning by water, mineral, and uric acid metabolism drugs
 Injuries & Poisonings 1.15 0.401 – 2.98 0.795 6 25 exclusion phecode
975
Poisoning by agents primarily acting on the
Poisoning by agents primarily acting on the smooth and skeletal muscles and respiratory system
 Injuries & Poisonings 0.287 0.0316 – 0.973 0.0864 7 31 exclusion phecode
976
Poisoning by agents primarily affecting skin &
Poisoning by agents primarily affecting skin & mucous membrane, ophthalmological, otorhinolaryngological, & dental drugs
 Injuries & Poisonings 1.01 0.163 – 5.15 0.988 4 16 exclusion phecode
977 Personal history of allergy to medicinal agents Injuries & Poisonings 1.01 0.753 – 1.3 0.969 66 411 exclusion phecode
979 Adverse drug events and drug allergies Injuries & Poisonings 0.81 0.665 – 0.974 0.0294 165 778 exclusion phecode
980
Encounter for long-term (current) use of
Encounter for long-term (current) use of antibiotics
 Infectious Diseases 0.851 0.584 – 1.16 0.349 45 263 exclusion phecode
985 Toxic effect of other metals Injuries & Poisonings 3.17 0.859 – 1430 0.155 3 20 exclusion phecode
989
Toxic effect of other substances, chiefly
Toxic effect of other substances, chiefly nonmedicinal as to source
 Injuries & Poisonings 1.07 0.466 – 2.39 0.873 7 41 exclusion phecode
990 Effects radiation NOS Injuries & Poisonings 1.12 0.897 – 1.37 0.296 94 669 exclusion phecode
994 Sepsis and SIRS Injuries & Poisonings 1.11 0.872 – 1.39 0.37 73 456 exclusion phecode
994.1 Systemic inflammatory response syndrome (SIRS) Injuries & Poisonings 1.01 0.359 – 2.5 0.986 10 64 exclusion phecode
994.2 Sepsis Injuries & Poisonings 1.1 0.854 – 1.38 0.449 69 423 exclusion phecode
994.21 Septic shock Injuries & Poisonings 0.904 0.446 – 1.62 0.739 14 111 exclusion phecode
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