Departments of Anesthesiology and Biostatistics | University of Michigan

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Scores HDL cholesterol (IRNT) Michigan Genomics Initiative Freeze 3 (MGI) PheWAS analysis

HDL cholesterol (IRNT) — Michigan Genomics Initiative Freeze 3 (MGI) PRS PheWAS

PRS model
PRS ID exprsweb-hdl-30760-irnt-dbslmm-mgi-freeze3-20211120Legacy DBSLMMDBSLMMUK Biobank GWAS

Evaluation cohort: Michigan Genomics Initiative Freeze 3 (MGI).

This page pairs the PheWAS plot with the full sortable table for the all-subject and exclusion scans.

Read the all-subject and exclusion scans separately. The combined view is only a browsing aid, and the selected-phecode panel below is only meaningful when the same phecode exists in both scans.

ExPRS exclusion definition

Exclusion cohort: normal-range subset (60-10000).

For this ExPRS, the exclusion sensitivity scan keeps only the study's normal-range subset for HDL cholesterol (IRNT) (60-10000) before rerunning the PheWAS. This is an exposure-based sensitivity analysis rather than a diagnosis-based exclusion.

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Signal overview

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342 rows visible 17 categories
Phecode Description Category OR 95% CI P value Cases Controls Analysis Link
008 Intestinal infection Infectious Diseases 1 0.966 – 1.04 0.86 3004 29292 all phecode
008.5 Bacterial enteritis Infectious Diseases 1.01 0.953 – 1.07 0.747 1322 13162 all phecode
008.52 Intestinal infection due to C. difficile Infectious Diseases 0.987 0.926 – 1.05 0.696 1046 10455 all phecode
008.6 Viral Enteritis Infectious Diseases 0.97 0.901 – 1.05 0.426 770 7676 all phecode
010 Tuberculosis Infectious Diseases 1 0.878 – 1.14 0.977 244 2425 all phecode
031 Diseases due to other mycobacteria Infectious Diseases 0.965 0.762 – 1.22 0.768 86 855 all phecode
038 Septicemia Infectious Diseases 0.955 0.917 – 0.995 0.0285 2582 24779 all phecode
038.1 Gram negative septicemia Infectious Diseases 0.889 0.814 – 0.971 0.00889 568 5629 all phecode
038.2 Gram positive septicemia Infectious Diseases 0.897 0.784 – 1.03 0.117 235 2350 all phecode
038.3 Bacteremia Infectious Diseases 0.941 0.886 – 1 0.0482 1210 12079 all phecode
041 Bacterial infection NOS Infectious Diseases 0.979 0.952 – 1.01 0.135 5750 38799 all phecode
041.1 Staphylococcus infections Infectious Diseases 0.956 0.909 – 1.01 0.0813 1707 16977 all phecode
041.11 Methicillin sensitive Staphylococcus aureus Infectious Diseases 0.957 0.893 – 1.03 0.21 920 9192 all phecode
041.12 Methicillin resistant Staphylococcus aureus Infectious Diseases 0.94 0.873 – 1.01 0.105 783 7812 all phecode
041.2 Streptococcus infection Infectious Diseases 0.99 0.94 – 1.04 0.695 1632 16287 all phecode
041.21 Rheumatic fever / chorea Infectious Diseases 0.924 0.813 – 1.05 0.224 257 2554 all phecode
041.4 E. coli Infectious Diseases 0.998 0.939 – 1.06 0.943 1175 11680 all phecode
041.8 H. pylori Infectious Diseases 1.04 0.914 – 1.18 0.545 257 2521 all phecode
041.9 Infection with drug-resistant microorganisms Infectious Diseases 1 0.9 – 1.11 1 387 3864 all phecode
053 Herpes zoster Infectious Diseases 1.04 0.984 – 1.09 0.171 1560 15184 all phecode
053.1 Herpes zoster with nervous system complications Infectious Diseases 1.01 0.88 – 1.17 0.859 220 2169 all phecode
054 Herpes simplex Infectious Diseases 0.992 0.942 – 1.05 0.77 1593 15600 all phecode
070 Viral hepatitis Infectious Diseases 0.965 0.898 – 1.04 0.338 829 8280 all phecode
070.1 Viral hepatitis A Infectious Diseases 1.07 0.86 – 1.34 0.53 87 860 all phecode
070.2 Viral hepatitis B Infectious Diseases 1 0.869 – 1.16 0.966 215 2138 all phecode
070.3 Viral hepatitis C Infectious Diseases 0.909 0.832 – 0.994 0.0364 528 5280 all phecode
070.4 Chronic hepatitis Infectious Diseases 0.918 0.792 – 1.06 0.254 197 1964 all phecode
070.9 Hepatitis NOS Infectious Diseases 0.924 0.868 – 0.983 0.0118 1145 11381 all phecode
071 Human immunodeficiency virus [HIV] disease Infectious Diseases 0.847 0.712 – 1.01 0.0633 145 1450 all phecode
071.1 HIV infection, symptomatic Infectious Diseases 0.849 0.7 – 1.03 0.0976 117 1163 all phecode
078 Viral warts & HPV Infectious Diseases 1.01 0.978 – 1.05 0.446 3434 29624 all phecode
079 Viral infection Infectious Diseases 0.986 0.96 – 1.01 0.296 6664 35342 all phecode
079.1 Varicella infection Infectious Diseases 1 0.97 – 1.04 0.809 3793 31251 all phecode
079.2 Infectious mononucleosis Infectious Diseases 0.902 0.795 – 1.02 0.108 283 2723 all phecode
079.9 Viremia, NOS Infectious Diseases 0.888 0.826 – 0.955 0.00135 838 8253 all phecode
080 Postoperative infection Infectious Diseases 0.977 0.938 – 1.02 0.268 2619 26065 all phecode
081
Infection/inflammation of internal prosthetic
Infection/inflammation of internal prosthetic device; implant; and graft
 Infectious Diseases 0.977 0.927 – 1.03 0.377 1589 15884 all phecode
090
Sexually transmitted infections (not HIV or
Sexually transmitted infections (not HIV or hepatitis)
 Infectious Diseases 1.06 0.995 – 1.14 0.0677 965 9630 all phecode
110 Dermatophytosis / Dermatomycosis Infectious Diseases 1 0.966 – 1.04 0.927 3544 30054 all phecode
110.1 Dermatophytosis Infectious Diseases 0.999 0.962 – 1.04 0.964 3241 27244 all phecode
110.11 Dermatophytosis of nail Infectious Diseases 1.01 0.964 – 1.06 0.648 2044 16765 all phecode
110.12 Althete's foot Infectious Diseases 0.987 0.92 – 1.06 0.708 899 8043 all phecode
110.13 Dermatophytosis of the body Infectious Diseases 0.971 0.901 – 1.05 0.428 790 7827 all phecode
110.2 Dermatomycoses Infectious Diseases 0.997 0.897 – 1.11 0.961 398 3971 all phecode
112 Candidiasis Infectious Diseases 0.962 0.929 – 0.996 0.0305 3685 30495 all phecode
112.3 Candidiasis of skin and nails Infectious Diseases 0.958 0.885 – 1.04 0.287 682 6732 all phecode
117 Mycoses Infectious Diseases 1.01 0.927 – 1.1 0.854 608 6069 all phecode
117.1 Histoplasmosis Infectious Diseases 1.15 0.915 – 1.46 0.225 81 801 all phecode
117.4 Aspergillosis Infectious Diseases 1.12 0.941 – 1.34 0.198 140 1387 all phecode
130 Spirochetal infection Infectious Diseases 1.04 0.891 – 1.22 0.613 168 1677 all phecode
130.1 Lyme disease Infectious Diseases 1.04 0.862 – 1.25 0.694 116 1160 all phecode
131 Protozoan infection Infectious Diseases 1.07 0.812 – 1.4 0.637 61 610 all phecode
132 Infestation (lice, mites) Infectious Diseases 0.969 0.836 – 1.12 0.672 195 1948 all phecode
134 Helminthiases Infectious Diseases 0.87 0.692 – 1.09 0.235 83 812 all phecode
134.1 Intestinal helminthiases Infectious Diseases 0.756 0.561 – 1.02 0.0668 53 513 all phecode
136 Other infectious and parasitic diseases Infectious Diseases 0.981 0.946 – 1.02 0.295 3279 32486 all phecode
145 Cancer of mouth Neoplasms 1.04 0.988 – 1.1 0.131 1481 14725 all phecode
145.1 Cancer of lip Neoplasms 0.962 0.758 – 1.22 0.747 76 750 all phecode
145.2 Cancer of tongue Neoplasms 1.08 0.991 – 1.17 0.0808 645 6430 all phecode
145.3 Cancer of major salivary glands Neoplasms 1.02 0.917 – 1.14 0.69 361 3597 all phecode
145.4 Cancer of the gums Neoplasms 1.08 0.919 – 1.27 0.345 166 1632 all phecode
145.5 Cancer of the mouth floor Neoplasms 1.07 0.929 – 1.24 0.334 206 2048 all phecode
149 Cancer of larynx, pharynx, nasal cavities Neoplasms 1.01 0.956 – 1.07 0.653 1290 12873 all phecode
149.1 Cancer of oropharynx Neoplasms 1.04 0.932 – 1.16 0.473 350 3499 all phecode
149.2 Cancer of nasopharynx Neoplasms 0.936 0.763 – 1.15 0.53 100 1000 all phecode
149.3 Cancer of hypopharynx Neoplasms 1.1 0.888 – 1.37 0.37 82 819 all phecode
149.4 Cancer of larynx Neoplasms 0.984 0.886 – 1.09 0.769 386 3857 all phecode
149.5
Hx of malignant neoplasm of oral cavity and
Hx of malignant neoplasm of oral cavity and pharynx
 Neoplasms 1 0.918 – 1.1 0.951 552 5505 all phecode
149.9 Cancer of of nasal cavities Neoplasms 1.08 0.947 – 1.22 0.259 240 2398 all phecode
150 Cancer of esophagus Neoplasms 0.952 0.861 – 1.05 0.336 433 4315 all phecode
151 Cancer of stomach Neoplasms 1.02 0.932 – 1.12 0.628 498 4962 all phecode
153 Colorectal cancer Neoplasms 1.03 0.975 – 1.09 0.289 1458 14383 all phecode
153.2 Colon cancer Neoplasms 1.06 0.993 – 1.12 0.0807 1160 11472 all phecode
153.3
Malignant neoplasm of rectum, rectosigmoid
Malignant neoplasm of rectum, rectosigmoid junction, and anus
 Neoplasms 1.01 0.94 – 1.09 0.773 815 8093 all phecode
155 Cancer of liver and intrahepatic bile duct Neoplasms 0.926 0.845 – 1.01 0.0988 511 5097 all phecode
155.1 Malignant neoplasm of liver, primary Neoplasms 0.935 0.837 – 1.05 0.241 344 3433 all phecode
157 Pancreatic cancer Neoplasms 1.02 0.93 – 1.12 0.679 503 5005 all phecode
158
Neoplasm of unspecified nature of digestive
Neoplasm of unspecified nature of digestive system
 Neoplasms 0.994 0.944 – 1.05 0.809 1623 15759 all phecode
159
Malignant neoplasm of other and ill-defined
Malignant neoplasm of other and ill-defined sites within the digestive organs and peritoneum
 Neoplasms 1.02 0.974 – 1.07 0.365 1818 17869 all phecode
159.2
Malignant neoplasm of small intestine
Malignant neoplasm of small intestine, including duodenum
 Neoplasms 1.07 0.935 – 1.23 0.322 221 2206 all phecode
159.3
Malignant neoplasm of gallbladder and
Malignant neoplasm of gallbladder and extrahepatic bile ducts
 Neoplasms 0.999 0.844 – 1.18 0.987 158 1578 all phecode
159.4
Malignant neoplasm of retroperitoneum and
Malignant neoplasm of retroperitoneum and peritoneum
 Neoplasms 1.12 0.996 – 1.26 0.0588 293 2920 all phecode
164 Cancer of intrathoracic organs Neoplasms 1.02 0.859 – 1.22 0.796 133 1324 all phecode
165 Cancer within the respiratory system Neoplasms 1 0.949 – 1.06 0.879 1336 13340 all phecode
165.1 Cancer of bronchus; lung Neoplasms 1 0.941 – 1.07 0.929 1057 10552 all phecode
170 Cancer of bone and connective tissue Neoplasms 1.05 0.996 – 1.1 0.0723 1792 17850 all phecode
170.1 Bone cancer Neoplasms 1.04 0.967 – 1.12 0.282 773 7690 all phecode
170.2 Cancer of connective tissue Neoplasms 1.03 0.973 – 1.09 0.295 1266 12632 all phecode
172 Skin cancer Neoplasms 0.997 0.972 – 1.02 0.794 8608 33186 all phecode
172.1 Melanomas of skin, dx or hx Neoplasms 1 0.974 – 1.03 0.803 5330 30106 all phecode
172.11 Melanomas of skin Neoplasms 1.02 0.98 – 1.06 0.375 3100 25064 all phecode
172.2 Other non-epithelial cancer of skin Neoplasms 0.997 0.971 – 1.03 0.857 7095 30462 all phecode
172.21 Basal cell carcinoma Neoplasms 0.999 0.964 – 1.04 0.959 3690 23868 all phecode
172.22 Squamous cell carcinoma Neoplasms 0.993 0.951 – 1.04 0.746 2414 17683 all phecode
172.3 Carcinoma in situ of skin Neoplasms 1 0.948 – 1.06 0.96 1482 12326 all phecode
173 Neoplasm of uncertain behavior of skin Neoplasms 0.957 0.913 – 1 0.0678 1997 18755 all phecode
174 Breast cancer Neoplasms 1.05 1.01 – 1.09 0.0141 3186 15514 all phecode
174.1 Breast cancer [female] Neoplasms 1.05 1.01 – 1.1 0.00928 3036 14701 all phecode
174.11 Malignant neoplasm of female breast Neoplasms 1.06 1.01 – 1.1 0.00779 2991 14639 all phecode
174.3 Neoplasm of uncertain behavior of breast Neoplasms 0.962 0.839 – 1.1 0.579 233 2307 all phecode
175 Acquired absence of breast Neoplasms 1.01 0.947 – 1.09 0.688 919 8920 all phecode
180 Cervical cancer and dysplasia Neoplasms 1.05 0.989 – 1.1 0.117 1431 12185 all phecode
180.1 Cervical cancer Neoplasms 1.06 0.967 – 1.16 0.215 500 4982 all phecode
180.3
Cervical intraepithelial neoplasia [CIN]
Cervical intraepithelial neoplasia [CIN] [Cervical dysplasia]
 Neoplasms 1.05 0.987 – 1.12 0.117 1048 9323 all phecode
182 Malignant neoplasm of uterus Neoplasms 1.04 0.967 – 1.12 0.278 765 7613 all phecode
184 Cancer of other female genital organs Neoplasms 1.04 0.982 – 1.11 0.172 1191 11592 all phecode
184.1
Malignant neoplasm of ovary and other uterine
Malignant neoplasm of ovary and other uterine adnexa
 Neoplasms 1.09 1 – 1.19 0.044 573 5719 all phecode
184.11 Malignant neoplasm of ovary Neoplasms 1.06 0.961 – 1.17 0.239 432 4309 all phecode
184.2
Cancer of other female genital organs
Cancer of other female genital organs (excluding uterus and ovary)
 Neoplasms 1 0.923 – 1.09 0.923 608 6057 all phecode
185 Cancer of prostate Neoplasms 1.04 0.996 – 1.09 0.0754 2901 10342 all phecode
187 Cancer of other male genital organs Neoplasms 1.11 0.992 – 1.24 0.0697 339 3384 all phecode
187.1
Malignant neoplasm of unspecified male genital
Malignant neoplasm of unspecified male genital organ
 Neoplasms 1.11 0.92 – 1.34 0.274 115 1141 all phecode
187.2 Malignant neoplasm of testis Neoplasms 1.11 0.95 – 1.29 0.195 183 1830 all phecode
187.8
Neoplasm of uncertain behavior of male genital
Neoplasm of uncertain behavior of male genital organs
 Neoplasms 1.06 0.821 – 1.37 0.65 57 562 all phecode
189
Cancer of urinary organs (incl. kidney and
Cancer of urinary organs (incl. kidney and bladder)
 Neoplasms 0.957 0.92 – 0.995 0.0264 2923 23541 all phecode
189.1 Cancer of kidney and renal pelvis Neoplasms 0.94 0.89 – 0.993 0.0277 1450 14437 all phecode
189.11 Malignant neoplasm of kidney, except pelvis Neoplasms 0.915 0.862 – 0.97 0.00302 1267 12655 all phecode
189.12 Malignant neoplasm of renal pelvis Neoplasms 0.901 0.785 – 1.03 0.135 237 2347 all phecode
189.2 Cancer of bladder Neoplasms 0.963 0.916 – 1.01 0.134 1783 15224 all phecode
189.21 Malignant neoplasm of bladder Neoplasms 0.96 0.912 – 1.01 0.124 1657 14178 all phecode
189.4 Malignant neoplasm of other urinary organs Neoplasms 1.01 0.93 – 1.09 0.856 678 6586 all phecode
190 Cancer of eye Neoplasms 1.05 0.891 – 1.24 0.546 138 1374 all phecode
191
Manlignant and unknown neoplasms of brain and
Manlignant and unknown neoplasms of brain and nervous system
 Neoplasms 0.987 0.927 – 1.05 0.695 1078 10771 all phecode
191.1 Cancer of brain and nervous system Neoplasms 0.984 0.909 – 1.06 0.684 706 7052 all phecode
191.11 Cancer of brain Neoplasms 0.942 0.864 – 1.03 0.171 600 5996 all phecode
193 Thyroid cancer Neoplasms 0.968 0.905 – 1.04 0.351 945 9393 all phecode
194 Cancer of other endocrine glands Neoplasms 0.914 0.838 – 0.996 0.0405 579 5759 all phecode
195 Cancer, suspected or other Neoplasms 0.998 0.977 – 1.02 0.846 16962 26401 all phecode
195.1 Malignant neoplasm, other Neoplasms 0.999 0.978 – 1.02 0.918 16670 26384 all phecode
195.3 Malignant neoplasm of head, face, and neck Neoplasms 1.03 0.97 – 1.1 0.314 1103 9766 all phecode
196 Radiotherapy Neoplasms 1.05 1 – 1.09 0.036 2427 17006 all phecode
197 Chemotherapy Neoplasms 1.01 0.978 – 1.04 0.541 4952 23797 all phecode
198 Secondary malignant neoplasm Neoplasms 0.992 0.963 – 1.02 0.608 5801 23481 all phecode
198.1 Secondary malignancy of lymph nodes Neoplasms 0.992 0.957 – 1.03 0.664 3677 21489 all phecode
198.2 Secondary malignancy of respiratory organs Neoplasms 0.997 0.936 – 1.06 0.932 1072 10334 all phecode
198.3
Secondary malignant neoplasm of digestive
Secondary malignant neoplasm of digestive systems
 Neoplasms 0.978 0.911 – 1.05 0.528 866 8538 all phecode
198.4 Secondary malignant neoplasm of liver Neoplasms 0.998 0.927 – 1.08 0.967 767 7558 all phecode
198.5 Secondary malignancy of brain/spine Neoplasms 0.969 0.892 – 1.05 0.447 640 6338 all phecode
198.6 Secondary malignancy of bone Neoplasms 0.949 0.884 – 1.02 0.149 866 8307 all phecode
198.7 Secondary malignant neoplasm of skin Neoplasms 1.05 0.94 – 1.18 0.378 336 3253 all phecode
199 Neoplasm of uncertain behavior Neoplasms 1.01 0.977 – 1.04 0.639 5693 25767 all phecode
199.4 Neurofibromatosis Neoplasms 1.16 0.925 – 1.45 0.199 88 880 all phecode
200 Myeloproliferative disease Neoplasms 0.922 0.866 – 0.981 0.0102 1113 11098 all phecode
200.1 Polycythemia vera Neoplasms 0.886 0.775 – 1.01 0.0788 231 2310 all phecode
201 Hodgkin's disease Neoplasms 1.04 0.89 – 1.22 0.614 172 1705 all phecode
202 Cancer of other lymphoid, histiocytic tissue Neoplasms 0.993 0.942 – 1.05 0.798 1559 15571 all phecode
202.2 Non-Hodgkins lymphoma Neoplasms 1 0.946 – 1.06 0.961 1329 13268 all phecode
202.21 Nodular lymphoma Neoplasms 1.03 0.95 – 1.11 0.49 693 6923 all phecode
202.22 Reticulosarcoma Neoplasms 0.95 0.809 – 1.12 0.53 170 1693 all phecode
202.24 Large cell lymphoma Neoplasms 0.933 0.79 – 1.1 0.413 160 1586 all phecode
204 Leukemia Neoplasms 0.96 0.888 – 1.04 0.311 689 6876 all phecode
204.1 Lymphoid leukemia Neoplasms 0.975 0.852 – 1.11 0.708 236 2354 all phecode
204.11 Lymphoid leukemia, acute Neoplasms 0.98 0.774 – 1.24 0.865 74 734 all phecode
204.12 Lymphoid leukemia, chronic Neoplasms 1.02 0.873 – 1.19 0.806 173 1724 all phecode
204.2 Myeloid leukemia Neoplasms 0.892 0.787 – 1.01 0.073 265 2633 all phecode
204.21 Myeloid leukemia, acute Neoplasms 0.881 0.746 – 1.04 0.136 153 1516 all phecode
204.22 Myeloid leukemia, chronic Neoplasms 1.03 0.788 – 1.34 0.836 61 610 all phecode
204.4 Multiple myeloma Neoplasms 0.909 0.792 – 1.04 0.179 217 2162 all phecode
208 Benign neoplasm of colon Neoplasms 1.01 0.988 – 1.03 0.352 10303 34953 all phecode
209 Neuroendocrine tumors Neoplasms 0.976 0.858 – 1.11 0.715 258 2580 all phecode
210 Benign neoplasm of lip, oral cavity, and pharynx Neoplasms 1.02 0.973 – 1.07 0.395 1891 18839 all phecode
211
Benign neoplasm of other parts of digestive
Benign neoplasm of other parts of digestive system
 Neoplasms 0.979 0.954 – 1 0.0957 7329 36606 all phecode
212
Benign neoplasm of respiratory and
Benign neoplasm of respiratory and intrathoracic organs
 Neoplasms 0.967 0.922 – 1.02 0.177 1843 18412 all phecode
213 Benign neoplasm of bone and articular cartilage Neoplasms 0.966 0.918 – 1.02 0.187 1677 15527 all phecode
214 Lipoma Neoplasms 0.997 0.944 – 1.05 0.91 1437 14132 all phecode
214.1 Lipoma of skin and subcutaneous tissue Neoplasms 0.997 0.93 – 1.07 0.922 883 8710 all phecode
215
Other benign neoplasm of connective and other
Other benign neoplasm of connective and other soft tissue
 Neoplasms 0.992 0.961 – 1.02 0.599 4528 39509 all phecode
216 Benign neoplasm of skin Neoplasms 1 0.98 – 1.02 0.907 11528 34919 all phecode
216.1 Screening for malignant neoplasms of the skin Neoplasms 0.985 0.842 – 1.15 0.848 174 1701 all phecode
217 Vascular hamartomas and non-neoplastic nevi Neoplasms 1.04 0.994 – 1.1 0.0853 1786 17184 all phecode
217.1 Nevus, non-neoplastic Neoplasms 1.04 0.984 – 1.09 0.184 1679 16116 all phecode
218 Benign neoplasm of uterus Neoplasms 1.02 0.986 – 1.06 0.245 4301 16661 all phecode
218.1 Uterine leiomyoma Neoplasms 0.999 0.951 – 1.05 0.972 1835 15733 all phecode
218.2 Other benign neoplasm of uterus Neoplasms 1.03 0.989 – 1.07 0.16 3403 16447 all phecode
220 Benign neoplasm of ovary Neoplasms 0.986 0.92 – 1.06 0.7 893 8783 all phecode
221 Benign neoplasm of other female genital organs Neoplasms 0.992 0.947 – 1.04 0.748 2042 14248 all phecode
222 Benign neoplasm of male genital organs Neoplasms 1 0.941 – 1.07 0.966 1133 10663 all phecode
223
Benign neoplasm of kidney and other urinary
Benign neoplasm of kidney and other urinary organs
 Neoplasms 1 0.954 – 1.05 0.901 1801 12657 all phecode
224 Benign neoplasm of eye Neoplasms 0.993 0.918 – 1.07 0.863 691 6752 all phecode
224.1 Benign neoplasm of eye, uveal Neoplasms 0.987 0.906 – 1.07 0.762 595 5773 all phecode
225
Benign neoplasm of brain and other parts of
Benign neoplasm of brain and other parts of nervous system
 Neoplasms 1.05 0.992 – 1.12 0.0927 1209 12074 all phecode
225.1
Benign neoplasm of brain, cranial nerves
Benign neoplasm of brain, cranial nerves, meninges
 Neoplasms 1.09 1.02 – 1.17 0.0109 947 9454 all phecode
225.2 Benign neoplasm of spinal cord, meninges Neoplasms 0.899 0.795 – 1.02 0.0919 289 2890 all phecode
226 Benign neoplasm of thyroid glands Neoplasms 0.951 0.899 – 1.01 0.0838 1329 13264 all phecode
227
Benign neoplasm of other endocrine glands and
Benign neoplasm of other endocrine glands and related structures
 Neoplasms 1.03 0.977 – 1.08 0.287 1690 16896 all phecode
227.1 Benign neoplasm of adrenal gland Neoplasms 1.01 0.922 – 1.12 0.766 467 4644 all phecode
227.2 Benign neoplasm of parathyroid gland Neoplasms 1.01 0.943 – 1.09 0.702 795 7941 all phecode
227.3
Benign neoplasm of pituitary gland and
Benign neoplasm of pituitary gland and craniopharyngeal duct (pouch)
 Neoplasms 1.06 0.955 – 1.17 0.291 435 4350 all phecode
228 Hemangioma and lymphangioma, any site Neoplasms 1.05 1 – 1.1 0.0442 2149 20946 all phecode
228.1 Hemangioma of skin and subcutaneous tissue Neoplasms 1.05 0.99 – 1.11 0.108 1356 13336 all phecode
229 Benign neoplasm of unspecified sites Neoplasms 1.03 1.01 – 1.06 0.0115 7767 36615 all phecode
229.1 Benign neoplasm of lymph nodes Neoplasms 1.03 1.01 – 1.06 0.0181 5743 34218 all phecode
240 Simple and unspecified goiter Endocrine/metabolic 0.966 0.905 – 1.03 0.3 1031 9761 all phecode
241 Nontoxic nodular goiter Endocrine/metabolic 0.958 0.921 – 0.996 0.0317 2910 22227 all phecode
241.1 Nontoxic uninodular goiter Endocrine/metabolic 0.955 0.914 – 0.998 0.0419 2265 19902 all phecode
241.2 Nontoxic multinodular goiter Endocrine/metabolic 0.921 0.869 – 0.976 0.00535 1304 12479 all phecode
242 Thyrotoxicosis with or without goiter Endocrine/metabolic 0.95 0.898 – 1 0.0715 1400 13425 all phecode
242.1 Graves' disease Endocrine/metabolic 0.968 0.881 – 1.06 0.499 515 5068 all phecode
242.2 Toxic multinodular goiter Endocrine/metabolic 0.877 0.73 – 1.05 0.16 124 1224 all phecode
242.3 Exophthalmos Endocrine/metabolic 0.97 0.859 – 1.09 0.621 292 2898 all phecode
242.31 Thyrotoxic exophthalmos Endocrine/metabolic 0.973 0.819 – 1.16 0.756 144 1432 all phecode
244 Hypothyroidism Endocrine/metabolic 0.962 0.938 – 0.987 0.00299 8099 32717 all phecode
244.1 Secondary hypothyroidism Endocrine/metabolic 0.983 0.936 – 1.03 0.505 1762 17230 all phecode
244.2 Acquired hypothyroidism Endocrine/metabolic 0.971 0.916 – 1.03 0.329 1261 11982 all phecode
244.4 Hypothyroidism NOS Endocrine/metabolic 0.963 0.938 – 0.988 0.00439 7542 32208 all phecode
245 Thyroiditis Endocrine/metabolic 0.975 0.906 – 1.05 0.491 832 7882 all phecode
245.2 Chronic thyroiditis Endocrine/metabolic 0.98 0.904 – 1.06 0.612 686 6517 all phecode
245.21 Chronic lymphocytic thyroiditis Endocrine/metabolic 0.98 0.904 – 1.06 0.615 679 6449 all phecode
246 Other disorders of thyroid Endocrine/metabolic 0.966 0.939 – 0.994 0.0176 6129 30240 all phecode
246.2 Thyroid cyst Endocrine/metabolic 0.92 0.741 – 1.14 0.45 101 960 all phecode
246.7 Abnormal results of function study of thyroid Endocrine/metabolic 1.03 0.961 – 1.11 0.392 886 8696 all phecode
249 Secondary diabetes mellitus Endocrine/metabolic 0.81 0.755 – 0.869 4.42e-09 1150 8340 all phecode
250 Diabetes mellitus Endocrine/metabolic 0.878 0.859 – 0.898 2.69e-31 13947 31815 all phecode
250.1 Type 1 diabetes Endocrine/metabolic 0.827 0.78 – 0.877 2.82e-10 2364 11758 all phecode
250.11 Type 1 diabetes with ketoacidosis Endocrine/metabolic 0.834 0.701 – 0.993 0.0409 262 960 all phecode
250.12 Type 1 diabetes with renal manifestations Endocrine/metabolic 0.808 0.72 – 0.907 0.000298 551 2686 all phecode
250.13 Type 1 diabetes with ophthalmic manifestations Endocrine/metabolic 0.834 0.749 – 0.929 0.000973 784 3018 all phecode
250.14 Type 1 diabetes with neurological manifestations Endocrine/metabolic 0.841 0.75 – 0.943 0.003 638 2675 all phecode
250.15
Diabetes type 1 with peripheral circulatory
Diabetes type 1 with peripheral circulatory disorders
 Endocrine/metabolic 0.855 0.699 – 1.05 0.126 155 850 all phecode
250.2 Type 2 diabetes Endocrine/metabolic 0.842 0.821 – 0.864 6.06e-40 9843 29688 all phecode
250.21 Type 2 diabetes with ketoacidosis Endocrine/metabolic 0.788 0.677 – 0.918 0.00224 282 1327 all phecode
250.22 Type 2 diabetes with renal manifestations Endocrine/metabolic 0.807 0.764 – 0.852 1.51e-14 1941 13510 all phecode
250.23 Type 2 diabetes with ophthalmic manifestations Endocrine/metabolic 0.807 0.757 – 0.861 7.75e-11 1643 9668 all phecode
250.24 Type 2 diabetes with neurological manifestations Endocrine/metabolic 0.824 0.785 – 0.866 1.95e-14 2557 16502 all phecode
250.25
Diabetes type 2 with peripheral circulatory
Diabetes type 2 with peripheral circulatory disorders
 Endocrine/metabolic 0.802 0.74 – 0.87 1.15e-07 860 6143 all phecode
250.3 Insulin pump user Endocrine/metabolic 0.808 0.774 – 0.844 1.1e-21 3496 20809 all phecode
250.4 Abnormal glucose Endocrine/metabolic 0.916 0.891 – 0.941 1.47e-10 8385 30645 all phecode
250.41 Impaired fasting glucose Endocrine/metabolic 0.914 0.868 – 0.962 0.000542 1870 15861 all phecode
250.42 Other abnormal glucose Endocrine/metabolic 0.912 0.886 – 0.938 1.35e-10 7553 30071 all phecode
250.5 Glycosuria or Acetonuria Endocrine/metabolic 0.856 0.712 – 1.03 0.0955 136 1067 all phecode
250.6 Polyneuropathy in diabetes Endocrine/metabolic 0.821 0.776 – 0.867 2.68e-12 2132 13390 all phecode
250.7 Diabetic retinopathy Endocrine/metabolic 0.907 0.858 – 0.959 0.000594 1691 10517 all phecode
251 Other disorders of pancreatic internal secretion Endocrine/metabolic 0.939 0.879 – 1 0.0643 991 8469 all phecode
251.1 Hypoglycemia Endocrine/metabolic 0.901 0.841 – 0.965 0.0028 1207 8570 all phecode
252 Disorders of parathyroid gland Endocrine/metabolic 0.974 0.932 – 1.02 0.228 2282 22119 all phecode
252.1 Hyperparathyroidism Endocrine/metabolic 0.976 0.932 – 1.02 0.285 2088 20335 all phecode
252.2 Hypoparathyroidism Endocrine/metabolic 0.992 0.906 – 1.09 0.866 508 5073 all phecode
253
Disorders of the pituitary gland and its
Disorders of the pituitary gland and its hypothalamic control
 Endocrine/metabolic 0.952 0.887 – 1.02 0.173 859 8544 all phecode
253.1 Pituitary hyperfunction Endocrine/metabolic 0.967 0.851 – 1.1 0.603 263 2621 all phecode
253.11 Acromegaly and gigantism Endocrine/metabolic 1.06 0.853 – 1.32 0.597 83 826 all phecode
253.2 Pituitary hypofunction Endocrine/metabolic 0.901 0.786 – 1.03 0.132 226 2250 all phecode
253.3 Diabetes insipidus Endocrine/metabolic 0.897 0.714 – 1.13 0.354 86 860 all phecode
253.4 Anterior pituitary disorders Endocrine/metabolic 0.766 0.634 – 0.925 0.00559 121 1209 all phecode
253.7 Other disorders of neurohypophysis Endocrine/metabolic 1.05 0.865 – 1.28 0.619 108 1080 all phecode
255 Disorders of adrenal glands Endocrine/metabolic 0.942 0.893 – 0.994 0.028 1506 14869 all phecode
255.1 Adrenal hyperfunction Endocrine/metabolic 0.968 0.869 – 1.08 0.555 373 3730 all phecode
255.11 Cushing's syndrome Endocrine/metabolic 0.98 0.842 – 1.14 0.799 183 1830 all phecode
255.12 Hyperaldosteronism Endocrine/metabolic 0.865 0.725 – 1.03 0.108 135 1350 all phecode
255.2 Adrenal hypofunction Endocrine/metabolic 0.965 0.888 – 1.05 0.397 626 6239 all phecode
255.21 Glucocorticoid deficiency Endocrine/metabolic 0.979 0.899 – 1.07 0.631 596 5941 all phecode
256 Ovarian dysfunction Endocrine/metabolic 0.932 0.876 – 0.991 0.0255 1146 10513 all phecode
256.4 Polycystic ovaries Endocrine/metabolic 0.908 0.84 – 0.981 0.0142 742 7128 all phecode
257 Testicular dysfunction Endocrine/metabolic 1 0.936 – 1.07 0.985 1015 9238 all phecode
257.1 Testicular hypofunction Endocrine/metabolic 1.01 0.94 – 1.08 0.877 983 8933 all phecode
258 Iatrogenic endocrine disorders Endocrine/metabolic 1.02 0.828 – 1.27 0.822 91 910 all phecode
258.1 Postablative ovarian failure Endocrine/metabolic 0.908 0.753 – 1.1 0.315 109 1090 all phecode
259 Other endocrine disorders Endocrine/metabolic 1.05 0.981 – 1.12 0.17 1038 10259 all phecode
260 Protein-calorie malnutrition Endocrine/metabolic 0.986 0.949 – 1.03 0.489 2880 26812 all phecode
260.1 Cachexia Endocrine/metabolic 0.996 0.881 – 1.13 0.946 292 2911 all phecode
260.2 severe protein-calorie malnutrition Endocrine/metabolic 1.01 0.958 – 1.06 0.767 1691 16847 all phecode
260.22 Nutritional marasmus Endocrine/metabolic 1.01 0.931 – 1.1 0.768 614 6140 all phecode
260.3 Adult failure to thrive Endocrine/metabolic 1 0.923 – 1.09 0.937 629 6236 all phecode
260.6 Anorexia Endocrine/metabolic 0.934 0.87 – 1 0.0637 868 8591 all phecode
260.7 Polyphagia Endocrine/metabolic 1.06 0.828 – 1.36 0.633 65 643 all phecode
261 Vitamin deficiency Endocrine/metabolic 0.974 0.95 – 1 0.0478 7718 35203 all phecode
261.1 Vitamin A deficiency Endocrine/metabolic 0.92 0.716 – 1.18 0.518 69 690 all phecode
261.2 Vitamin B-complex deficiencies Endocrine/metabolic 0.986 0.918 – 1.06 0.7 857 8405 all phecode
261.4 Vitamin D deficiency Endocrine/metabolic 0.978 0.953 – 1 0.103 7255 35225 all phecode
261.41 Rickets or osteomalacia Endocrine/metabolic 0.976 0.745 – 1.28 0.862 52 511 all phecode
262 Mineral deficiency NEC Endocrine/metabolic 0.933 0.878 – 0.991 0.0254 1182 11676 all phecode
263 Other nutritional deficiency Endocrine/metabolic 1 0.949 – 1.05 0.992 1651 15788 all phecode
264 Lack of normal physiological development Endocrine/metabolic 1.07 0.938 – 1.23 0.305 239 2301 all phecode
264.2 Failure to thrive (childhood) Endocrine/metabolic 1.15 0.959 – 1.39 0.131 122 1220 all phecode
264.9
Lack of normal physiological development
Lack of normal physiological development, unspecified
 Endocrine/metabolic 1.05 0.841 – 1.3 0.678 81 772 all phecode
269 Proteinuria Endocrine/metabolic 0.9 0.855 – 0.947 5.66e-05 1694 13981 all phecode
270
Disorders of protein plasma/amino-acid
Disorders of protein plasma/amino-acid transport and metabolism
 Endocrine/metabolic 0.938 0.877 – 1 0.0602 967 9575 all phecode
270.1 Disturbances of amino-acid transport Endocrine/metabolic 0.86 0.733 – 1.01 0.0668 170 1697 all phecode
270.11
Disturbances of sulphur-bearing amino-acid
Disturbances of sulphur-bearing amino-acid metabolism
 Endocrine/metabolic 0.877 0.733 – 1.05 0.151 134 1334 all phecode
270.2 Disorders of amino-acid metabolism Endocrine/metabolic 0.915 0.737 – 1.13 0.417 96 954 all phecode
270.3 Disorders of plasma protein metabolism Endocrine/metabolic 0.956 0.886 – 1.03 0.256 737 7303 all phecode
270.32 Paraproteinemia Endocrine/metabolic 0.889 0.798 – 0.99 0.0314 384 3781 all phecode
270.33 Amyloidosis Endocrine/metabolic 1.04 0.804 – 1.33 0.785 71 695 all phecode
270.34 Alpha-1-antitrypsin deficiency Endocrine/metabolic 0.979 0.766 – 1.25 0.868 69 690 all phecode
270.38
Other specified disorders of plasma protein
Other specified disorders of plasma protein metabolism
 Endocrine/metabolic 0.994 0.883 – 1.12 0.923 299 2984 all phecode
271
Disorders of carbohydrate transport and
Disorders of carbohydrate transport and metabolism
 Endocrine/metabolic 0.979 0.942 – 1.02 0.282 2907 28132 all phecode
271.3
Intestinal disaccharidase deficiencies and
Intestinal disaccharidase deficiencies and disaccharide malabsorption
 Endocrine/metabolic 0.982 0.944 – 1.02 0.364 2827 27425 all phecode
271.9
Other disorders of carbohydrate transport and
Other disorders of carbohydrate transport and metabolism
 Endocrine/metabolic 0.808 0.659 – 0.99 0.0398 102 1007 all phecode
272 Disorders of lipoid metabolism Endocrine/metabolic 0.864 0.846 – 0.883 2.8e-42 18881 26670 all phecode
272.1 Hyperlipidemia Endocrine/metabolic 0.865 0.847 – 0.883 4.35e-42 18843 26654 all phecode
272.11 Hypercholesterolemia Endocrine/metabolic 0.881 0.854 – 0.909 2.31e-15 5928 21600 all phecode
272.12 Hyperglyceridemia Endocrine/metabolic 0.665 0.627 – 0.706 5.65e-42 1360 11837 all phecode
272.13 Mixed hyperlipidemia Endocrine/metabolic 0.851 0.818 – 0.885 8.42e-16 3538 18449 all phecode
272.9 Unspecified disorder of lipoid metabolism Endocrine/metabolic 0.855 0.761 – 0.962 0.00896 313 3011 all phecode
274 Gout and other crystal arthropathies Endocrine/metabolic 0.891 0.854 – 0.929 6.21e-08 2524 22729 all phecode
274.1 Gout Endocrine/metabolic 0.888 0.851 – 0.927 6.35e-08 2409 21991 all phecode
274.11 Gouty arthropathy Endocrine/metabolic 0.922 0.865 – 0.983 0.0128 1082 10576 all phecode
274.2 Crystal arthropathies Endocrine/metabolic 0.992 0.853 – 1.15 0.914 195 1890 all phecode
274.21 Chondrocalcinosis Endocrine/metabolic 1 0.857 – 1.17 0.988 183 1772 all phecode
275 Disorders of mineral metabolism Endocrine/metabolic 0.966 0.936 – 0.997 0.0341 4357 37091 all phecode
275.1 Disorders of iron metabolism Hematopoietic 0.936 0.815 – 1.07 0.348 218 2180 all phecode
275.11 Hereditary hemochromatosis Hematopoietic 0.99 0.812 – 1.21 0.919 99 990 all phecode
275.2 Disorders of copper metabolism Endocrine/metabolic 1.05 0.807 – 1.38 0.697 62 614 all phecode
275.3 Disorders of magnesium metabolism Endocrine/metabolic 0.957 0.9 – 1.02 0.156 1154 11504 all phecode
275.5 Disorders of calcium/phosphorus metabolism Endocrine/metabolic 0.966 0.932 – 1 0.0625 3369 31544 all phecode
275.51 Hypocalcemia Endocrine/metabolic 0.956 0.892 – 1.02 0.2 898 8969 all phecode
275.53 Disorders of phosphorus metabolism Endocrine/metabolic 0.973 0.919 – 1.03 0.334 1366 13634 all phecode
275.6 Hypercalcemia Endocrine/metabolic 0.952 0.901 – 1 0.0746 1468 14183 all phecode
276
Disorders of fluid, electrolyte, and acid-base
Disorders of fluid, electrolyte, and acid-base balance
 Endocrine/metabolic 0.97 0.948 – 0.993 0.0122 9238 37046 all phecode
276.1 Electrolyte imbalance Endocrine/metabolic 0.958 0.932 – 0.985 0.00245 6352 34366 all phecode
276.11 Hyperosmolality and/or hypernatremia Endocrine/metabolic 0.929 0.85 – 1.02 0.106 550 5434 all phecode
276.12 Hyposmolality and/or hyponatremia Endocrine/metabolic 0.963 0.924 – 1 0.0777 2514 23219 all phecode
276.13 Hyperpotassemia Endocrine/metabolic 0.956 0.921 – 0.994 0.0226 2992 25216 all phecode
276.14 Hypopotassemia Endocrine/metabolic 0.952 0.91 – 0.996 0.0326 2148 20909 all phecode
276.4 Acid-base balance disorder Endocrine/metabolic 0.94 0.898 – 0.984 0.00787 2086 20332 all phecode
276.41 Acidosis Endocrine/metabolic 0.921 0.877 – 0.967 0.00102 1788 17572 all phecode
276.42 Alkalosis Endocrine/metabolic 1.04 0.946 – 1.14 0.419 476 4741 all phecode
276.5 Hypovolemia Endocrine/metabolic 0.967 0.937 – 0.998 0.0371 4574 34527 all phecode
276.6 Fluid overload Endocrine/metabolic 0.917 0.867 – 0.969 0.00215 1384 13211 all phecode
276.8 Polydipsia Endocrine/metabolic 0.838 0.697 – 1.01 0.0611 124 1240 all phecode
277 Other disorders of metabolism Endocrine/metabolic 0.911 0.881 – 0.941 2.83e-08 4112 35070 all phecode
277.2
Other disorders of purine and pyrimidine
Other disorders of purine and pyrimidine metabolism
 Endocrine/metabolic 0.942 0.85 – 1.04 0.251 403 3991 all phecode
277.4 Disorders of bilirubin excretion Endocrine/metabolic 0.97 0.898 – 1.05 0.444 720 7161 all phecode
277.5 Other disorders of lipoid metabolism Endocrine/metabolic 0.777 0.725 – 0.832 7.15e-13 936 9270 all phecode
277.51 Lipoprotein disorders Endocrine/metabolic 0.747 0.692 – 0.806 4.41e-14 773 7668 all phecode
277.7 Dysmetabolic syndrome X Endocrine/metabolic 0.859 0.801 – 0.921 1.9e-05 916 8359 all phecode
278 Overweight, obesity and other hyperalimentation Endocrine/metabolic 0.919 0.902 – 0.937 1.84e-18 19419 27331 all phecode
278.1 Obesity Endocrine/metabolic 0.906 0.888 – 0.924 4.78e-23 17129 27321 all phecode
278.11 Morbid obesity Endocrine/metabolic 0.901 0.878 – 0.924 5.68e-16 8280 27172 all phecode
278.3 Localized adiposity Endocrine/metabolic 0.862 0.768 – 0.968 0.0118 324 3228 all phecode
278.4 Abnormal weight gain Endocrine/metabolic 0.948 0.905 – 0.993 0.0241 2104 17411 all phecode
279 Disorders involving the immune mechanism Endocrine/metabolic 0.977 0.94 – 1.02 0.241 2934 28612 all phecode
279.1 Immunity deficiency Endocrine/metabolic 0.992 0.933 – 1.05 0.793 1161 11571 all phecode
279.11 Deficiency of humoral immunity Endocrine/metabolic 1.03 0.919 – 1.16 0.602 330 3278 all phecode
279.2 Autoimmune disease NEC Endocrine/metabolic 0.958 0.888 – 1.03 0.271 754 7516 all phecode
279.7 Other immunological findings Endocrine/metabolic 0.949 0.92 – 0.978 0.000739 4885 36552 all phecode
279.8
Other specified disorders involving the immune
Other specified disorders involving the immune mechanism
 Endocrine/metabolic 0.945 0.868 – 1.03 0.187 601 5988 all phecode
280 Iron deficiency anemias Hematopoietic 0.948 0.919 – 0.979 0.000946 4626 30873 all phecode
280.1
Iron deficiency anemias, unspecified or not due
Iron deficiency anemias, unspecified or not due to blood loss
 Hematopoietic 0.944 0.914 – 0.975 0.000424 4484 30649 all phecode
280.2
Iron deficiency anemia secondary to blood loss
Iron deficiency anemia secondary to blood loss (chronic)
 Hematopoietic 0.963 0.917 – 1.01 0.135 1771 17196 all phecode
281 Other deficiency anemia Hematopoietic 0.905 0.826 – 0.992 0.0325 519 5120 all phecode
281.1 Megaloblastic anemia Hematopoietic 0.795 0.696 – 0.907 0.000648 253 2497 all phecode
281.11 Pernicious anemia Hematopoietic 0.716 0.587 – 0.874 0.00102 114 1108 all phecode
281.12 Other vitamin B12 deficiency anemia Hematopoietic 0.798 0.686 – 0.929 0.00366 187 1817 all phecode
281.9 Deficiency anemias Hematopoietic 0.953 0.843 – 1.08 0.448 285 2830 all phecode
282 Hereditary hemolytic anemias Hematopoietic 0.916 0.815 – 1.03 0.144 323 3188 all phecode
282.8 Other hemoglobinopathies Hematopoietic 0.902 0.782 – 1.04 0.155 216 2113 all phecode
282.9 Other hereditary hemolytic anemias Hematopoietic 0.854 0.735 – 0.992 0.0393 192 1920 all phecode
283 Acquired hemolytic anemias Hematopoietic 0.96 0.815 – 1.13 0.629 155 1550 all phecode
283.1 Autoimmune hemolytic anemias Hematopoietic 1.12 0.869 – 1.44 0.382 64 633 all phecode
284 Aplastic anemia Hematopoietic 0.914 0.844 – 0.989 0.0262 697 6943 all phecode
284.1 Pancytopenia Hematopoietic 0.882 0.81 – 0.96 0.0037 612 6100 all phecode
285 Other anemias Hematopoietic 0.961 0.941 – 0.982 0.000362 11794 33591 all phecode
285.1 Acute posthemorrhagic anemia Hematopoietic 0.948 0.914 – 0.983 0.00409 3325 27709 all phecode
285.2 Anemia of chronic disease Hematopoietic 0.944 0.902 – 0.989 0.0147 2055 19939 all phecode
285.21 Anemia in chronic kidney disease Hematopoietic 0.883 0.825 – 0.945 0.000345 932 9106 all phecode
285.22 Anemia in neoplastic disease Hematopoietic 1.02 0.947 – 1.11 0.555 690 6892 all phecode
286 Coagulation defects Hematopoietic 0.936 0.905 – 0.968 0.000132 3844 33384 all phecode
286.1 Congenital coagulation defects Hematopoietic 0.996 0.871 – 1.14 0.959 250 2466 all phecode
286.11 Von willebrand's disease Hematopoietic 0.925 0.738 – 1.16 0.5 83 822 all phecode
286.12
Congenital deficiency of other clotting factors
Congenital deficiency of other clotting factors (including factor VII)
 Hematopoietic 1.12 0.921 – 1.35 0.263 126 1260 all phecode
286.2
Encounter for long-term (current) use of
Encounter for long-term (current) use of anticoagulants
 Hematopoietic 0.956 0.921 – 0.991 0.0152 3354 25918 all phecode
286.3
Coagulation defects complicating pregnancy or
Coagulation defects complicating pregnancy or postpartum
 Hematopoietic 1.17 0.941 – 1.44 0.16 97 962 all phecode
286.4 Acquired coagulation factor deficiency Hematopoietic 0.949 0.834 – 1.08 0.424 254 2529 all phecode
286.5
Hemorrhagic disorder due to intrinsic
Hemorrhagic disorder due to intrinsic circulating anticoagulants
 Hematopoietic 1.18 0.99 – 1.42 0.065 132 1294 all phecode
286.6 Defibrination syndrome Hematopoietic 0.952 0.914 – 0.992 0.018 2579 25377 all phecode
286.7 Other and unspecified coagulation defects Hematopoietic 0.934 0.899 – 0.97 0.00044 3014 29294 all phecode
286.8 Hypercoagulable state Hematopoietic 0.981 0.912 – 1.05 0.595 846 8437 all phecode
286.81 Primary hypercoagulable state Hematopoietic 0.987 0.917 – 1.06 0.729 813 8111 all phecode
286.9 Abnormal coagulation profile Hematopoietic 0.936 0.88 – 0.994 0.0323 1182 11487 all phecode
287 Purpura and other hemorrhagic conditions Hematopoietic 0.918 0.885 – 0.952 4.37e-06 3288 28474 all phecode
287.1 Spontaneous ecchymoses Hematopoietic 0.955 0.825 – 1.1 0.53 211 2094 all phecode
287.3 Thrombocytopenia Hematopoietic 0.919 0.884 – 0.956 2.07e-05 2938 26323 all phecode
287.31 Primary thrombocytopenia Hematopoietic 0.907 0.834 – 0.987 0.0242 601 5994 all phecode
287.32 Secondary thrombocytopenia Hematopoietic 0.948 0.869 – 1.04 0.235 569 5686 all phecode
287.4 Qualitative platelet defects Hematopoietic 0.865 0.71 – 1.05 0.147 112 1120 all phecode
288 Diseases of white blood cells Hematopoietic 0.981 0.952 – 1.01 0.224 4886 36527 all phecode
288.1 Decreased white blood cell count Hematopoietic 1 0.951 – 1.05 0.965 1599 15951 all phecode
288.11 Neutropenia Hematopoietic 0.958 0.9 – 1.02 0.174 1106 11041 all phecode
288.2 Elevated white blood cell count Hematopoietic 0.985 0.953 – 1.02 0.364 4082 35079 all phecode
288.3 Eosinophilia Hematopoietic 1.12 0.962 – 1.3 0.148 187 1866 all phecode
289 Other diseases of blood and blood-forming organs Hematopoietic 1.01 0.962 – 1.06 0.674 1757 17434 all phecode
289.3
Personal history of diseases of blood and
Personal history of diseases of blood and blood-forming organs
 Hematopoietic 0.972 0.907 – 1.04 0.415 918 9087 all phecode
289.4 Lymphadenitis Hematopoietic 0.984 0.952 – 1.02 0.353 3888 34715 all phecode
289.5 Diseases of spleen Hematopoietic 1 0.902 – 1.11 0.983 393 3913 all phecode
289.8 Polycythemia, secondary Hematopoietic 0.863 0.759 – 0.982 0.0253 255 2550 all phecode
289.9 Abnormality of red blood cells Hematopoietic 1.07 0.96 – 1.19 0.228 385 3813 all phecode
290
Delirium dementia and amnestic and other
Delirium dementia and amnestic and other cognitive disorders
 Mental Disorders 0.99 0.935 – 1.05 0.735 1318 11547 all phecode
290.1 Dementias Mental Disorders 1.01 0.92 – 1.1 0.874 541 4910 all phecode
290.11 Alzheimer's disease Mental Disorders 0.975 0.821 – 1.16 0.777 151 1389 all phecode
290.12 Dementia with cerebral degenerations Mental Disorders 1.32 1.06 – 1.64 0.0138 88 846 all phecode
290.13 Senile dementia Mental Disorders 0.957 0.854 – 1.07 0.451 340 3078 all phecode
290.16 Vascular dementia Mental Disorders 0.991 0.791 – 1.24 0.94 81 777 all phecode
290.2 Delirium due to conditions classified elsewhere Mental Disorders 0.981 0.909 – 1.06 0.621 750 7358 all phecode
290.3
Other persistent mental disorders due to
Other persistent mental disorders due to conditions classified elsewhere
 Mental Disorders 0.975 0.909 – 1.05 0.481 886 8618 all phecode
291
Other specified nonpsychotic and/or transient
Other specified nonpsychotic and/or transient mental disorders
 Mental Disorders 0.964 0.925 – 1 0.0832 2550 24810 all phecode
291.1
Transient mental disorders due to conditions
Transient mental disorders due to conditions classified elsewhere
 Mental Disorders 1.11 0.951 – 1.31 0.18 175 1750 all phecode
291.4
Specific nonpsychotic mental disorders due to
Specific nonpsychotic mental disorders due to brain damage
 Mental Disorders 0.976 0.888 – 1.07 0.614 484 4807 all phecode
291.8 Alteration of consciousness Mental Disorders 0.951 0.908 – 0.996 0.0332 2036 19974 all phecode
292 Neurological disorders Mental Disorders 0.987 0.96 – 1.02 0.38 5733 38553 all phecode
292.1 Aphasia/speech disturbance Mental Disorders 1 0.958 – 1.05 0.88 2013 19867 all phecode
292.11 Aphasia Mental Disorders 1.01 0.929 – 1.09 0.857 664 6581 all phecode
292.12 Symbolic dysfunction Mental Disorders 0.94 0.811 – 1.09 0.416 200 1988 all phecode
292.2 Mild cognitive impairment Mental Disorders 0.97 0.873 – 1.08 0.568 389 3731 all phecode
292.3 Memory loss Mental Disorders 0.988 0.942 – 1.04 0.619 1922 18158 all phecode
292.4 Altered mental status Mental Disorders 0.949 0.91 – 0.99 0.0143 2454 22725 all phecode
292.5 Transient alteration of awareness Mental Disorders 0.991 0.896 – 1.1 0.86 430 4285 all phecode
292.6 Hallucinations Mental Disorders 0.962 0.833 – 1.11 0.592 217 2147 all phecode
293 Symptoms involving head and neck Mental Disorders 1.1 0.995 – 1.22 0.0612 414 4127 all phecode
293.1
Swelling, mass, or lump in head and neck
Swelling, mass, or lump in head and neck [Space-occupying lesion, intracranial NOS]
 Mental Disorders 0.959 0.929 – 0.99 0.00901 4417 38609 all phecode
295 Schizophrenia and other psychotic disorders Mental Disorders 0.973 0.907 – 1.04 0.453 885 8229 all phecode
295.1 Schizophrenia Mental Disorders 1.09 0.916 – 1.31 0.318 138 1339 all phecode
295.2 Paranoid disorders Mental Disorders 0.994 0.82 – 1.2 0.949 118 1079 all phecode
295.3 Psychosis Mental Disorders 0.962 0.89 – 1.04 0.335 716 6694 all phecode
296 Mood disorders Mental Disorders 0.975 0.954 – 0.996 0.0202 15356 20858 all phecode
296.1 Bipolar Mental Disorders 0.948 0.894 – 1.01 0.0801 1301 11264 all phecode
296.2 Depression Mental Disorders 0.976 0.955 – 0.997 0.0272 14833 20856 all phecode
296.22 Major depressive disorder Mental Disorders 0.975 0.953 – 0.997 0.0241 13850 20853 all phecode
297 Suicidal ideation or attempt Mental Disorders 0.95 0.887 – 1.02 0.135 985 9050 all phecode
297.1 Suicidal ideation Mental Disorders 0.945 0.876 – 1.02 0.143 788 7310 all phecode
297.2 Suicide or self-inflicted injury Mental Disorders 0.965 0.85 – 1.09 0.577 285 2654 all phecode
300 Anxiety disorders Mental Disorders 0.993 0.971 – 1.01 0.51 15419 20850 all phecode
300.1 Anxiety disorder Mental Disorders 0.991 0.97 – 1.01 0.431 14517 20855 all phecode
300.11 Generalized anxiety disorder Mental Disorders 0.99 0.959 – 1.02 0.513 5546 20512 all phecode
300.12 Agorophobia, social phobia, and panic disorder Mental Disorders 0.992 0.934 – 1.05 0.787 1360 11377 all phecode
300.13 Phobia Mental Disorders 1.01 0.941 – 1.07 0.861 1051 9542 all phecode
300.3 Obsessive-compulsive disorders Mental Disorders 1.05 0.934 – 1.19 0.405 328 3018 all phecode
300.4 Dysthymic disorder Mental Disorders 0.997 0.954 – 1.04 0.896 2420 16552 all phecode
300.8 Acute reaction to stress Mental Disorders 0.948 0.863 – 1.04 0.261 504 4825 all phecode
300.9 Posttraumatic stress disorder Mental Disorders 0.966 0.898 – 1.04 0.36 843 7909 all phecode
301 Personality disorders Mental Disorders 0.961 0.872 – 1.06 0.416 477 4539 all phecode
301.2 Antisocial/borderline personality disorder Mental Disorders 0.925 0.809 – 1.06 0.258 254 2393 all phecode
302 Sexual and gender identity disorders Mental Disorders 0.998 0.961 – 1.04 0.907 3700 13808 all phecode
302.1 Decreased libido Mental Disorders 0.95 0.859 – 1.05 0.311 447 4331 all phecode
303 Psychogenic and somatoform disorders Mental Disorders 0.991 0.963 – 1.02 0.543 6808 20043 all phecode
303.1 Dissociative disorder Mental Disorders 0.918 0.777 – 1.08 0.313 161 1573 all phecode
303.3 Psychogenic disorder Mental Disorders 0.998 0.969 – 1.03 0.878 6487 19888 all phecode
303.31
Gastrointestinal malfunction arising from
Gastrointestinal malfunction arising from mental factors
 Mental Disorders 0.985 0.895 – 1.09 0.764 471 4623 all phecode
303.4 Somatoform disorder Mental Disorders 0.96 0.903 – 1.02 0.195 1177 11180 all phecode
304 Adjustment reaction Mental Disorders 0.993 0.959 – 1.03 0.699 3888 20475 all phecode
305.2 Eating disorder Mental Disorders 0.98 0.913 – 1.05 0.564 901 8329 all phecode
306 Other mental disorder Mental Disorders 0.994 0.945 – 1.05 0.809 1815 14133 all phecode
306.1 Mental disorders durring/after pregnancy Mental Disorders 0.992 0.905 – 1.09 0.867 587 3527 all phecode
306.9 Tension headache Mental Disorders 0.964 0.892 – 1.04 0.356 753 7277 all phecode
312 Conduct disorders Mental Disorders 0.928 0.816 – 1.06 0.257 254 2501 all phecode
312.3 Impulse control disorder Mental Disorders 1 0.795 – 1.27 0.967 74 736 all phecode
313 Pervasive developmental disorders Mental Disorders 1.02 0.965 – 1.07 0.52 1571 14633 all phecode
313.1 Attention deficit hyperactivity disorder Mental Disorders 1.01 0.952 – 1.06 0.81 1392 13190 all phecode
313.2 Tics and stuttering Mental Disorders 0.872 0.692 – 1.1 0.244 77 770 all phecode
313.3 Autism Mental Disorders 1.04 0.801 – 1.34 0.789 64 621 all phecode
315 Develomental delays and disorders Mental Disorders 0.954 0.88 – 1.04 0.261 684 6788 all phecode
315.1 Learning disorder Mental Disorders 0.917 0.741 – 1.14 0.427 87 860 all phecode
315.2 Speech and language disorder Mental Disorders 1.03 0.904 – 1.18 0.64 254 2539 all phecode
316 Substance addiction and disorders Mental Disorders 1.01 0.973 – 1.04 0.665 3682 32680 all phecode
316.1 Polyneuropathy due to drugs Mental Disorders 1.1 1.01 – 1.19 0.0215 634 6331 all phecode
317 Alcohol-related disorders Mental Disorders 0.988 0.947 – 1.03 0.557 2525 22920 all phecode
317.1 Alcoholism Mental Disorders 1 0.956 – 1.05 0.928 1986 19339 all phecode
317.11 Alcoholic liver damage Mental Disorders 0.874 0.789 – 0.967 0.00891 408 4080 all phecode
318 Tobacco use disorder Mental Disorders 0.945 0.922 – 0.968 3.53e-06 8622 34842 all phecode
320 Meningitis Neurological 0.944 0.85 – 1.05 0.285 382 3820 all phecode
323 Encephalitis Neurological 1.13 0.97 – 1.31 0.119 181 1809 all phecode
323.8 Encephalitis, non-infectious Neurological 1.12 0.953 – 1.32 0.169 153 1527 all phecode
324 Other CNS infection and poliomyelitis Neurological 1.06 0.937 – 1.19 0.371 288 2880 all phecode
325
Phlebitis and thrombophlebitis of intracranial
Phlebitis and thrombophlebitis of intracranial venous sinuses
 Neurological 1.02 0.769 – 1.35 0.906 53 530 all phecode
327 Sleep disorders Neurological 0.949 0.93 – 0.968 2.78e-07 14941 31602 all phecode
327.1 Hypersomnia Neurological 0.973 0.929 – 1.02 0.251 2061 19110 all phecode
327.3 Sleep apnea Neurological 0.941 0.92 – 0.962 1.08e-07 10909 31304 all phecode
327.31 Central/nonobstroctive sleep apnea Neurological 0.92 0.839 – 1.01 0.0794 492 4784 all phecode
327.32 Obstructive sleep apnea Neurological 0.945 0.922 – 0.968 5.45e-06 8744 30530 all phecode
327.4 Insomnia Neurological 0.973 0.945 – 1 0.0721 5524 30960 all phecode
327.41 Organic or persistent insomnia Neurological 0.978 0.922 – 1.04 0.455 1265 12120 all phecode
327.5 Parasomnia Neurological 0.949 0.872 – 1.03 0.226 604 5913 all phecode
327.6 Circadian rhythm sleep disorder Neurological 0.955 0.842 – 1.08 0.477 274 2666 all phecode
327.7 Sleep related movement disorders Neurological 0.926 0.881 – 0.972 0.00209 1786 17323 all phecode
327.71 Restless legs syndrome Neurological 0.938 0.89 – 0.988 0.0158 1570 15360 all phecode
327.72 Sleep related leg cramps Neurological 0.87 0.692 – 1.09 0.235 83 822 all phecode
331 Other cerebral degenerations Neurological 0.956 0.884 – 1.03 0.259 717 7024 all phecode
331.1 Hydrocephalus Neurological 0.987 0.873 – 1.11 0.828 284 2836 all phecode
331.9 Cerebral degeneration, unspecified Neurological 0.916 0.827 – 1.02 0.095 419 4026 all phecode
332 Parkinson's disease Neurological 0.983 0.887 – 1.09 0.737 415 4128 all phecode
333
Extrapyramidal disease and abnormal movement
Extrapyramidal disease and abnormal movement disorders
 Neurological 0.98 0.943 – 1.02 0.316 2868 26583 all phecode
333.1 Essential tremor Neurological 1.03 0.949 – 1.11 0.519 725 7163 all phecode
333.2 Myoclonus Neurological 0.851 0.723 – 1 0.0547 159 1590 all phecode
333.4 Torsion dystonia Neurological 0.964 0.863 – 1.08 0.513 352 3504 all phecode
333.8 Other degenerative diseases of the basal ganglia Neurological 0.955 0.764 – 1.19 0.689 89 890 all phecode
334 Degenerative disease of the spinal cord Neurological 0.984 0.923 – 1.05 0.619 1058 10562 all phecode
334.1 Spinocerebellar disease Neurological 0.944 0.745 – 1.2 0.631 79 790 all phecode
334.2 Anterior horn cell disease Neurological 1 0.826 – 1.22 0.985 110 1080 all phecode
334.21 Amyotrophic Lateral Sclerosis Neurological 1.25 0.976 – 1.6 0.077 71 693 all phecode
335 Multiple sclerosis Neurological 0.944 0.85 – 1.05 0.283 396 3951 all phecode
337 Disorders of the autonomic nervous system Neurological 0.942 0.875 – 1.01 0.113 808 7413 all phecode
337.1 Peripheral autonomic neuropathy Neurological 0.93 0.834 – 1.04 0.19 370 3164 all phecode
338 Pain Neurological 0.984 0.966 – 1 0.0919 20346 26417 all phecode
338.1 Acute pain Neurological 0.983 0.963 – 1 0.0881 15582 26313 all phecode
338.2 Chronic pain Neurological 0.976 0.954 – 0.999 0.0369 10994 26368 all phecode
339 Other headache syndromes Neurological 0.973 0.95 – 0.996 0.0242 9242 34658 all phecode
340 Migraine Neurological 0.957 0.931 – 0.983 0.00153 6708 30587 all phecode
340.1 Migrain with aura Neurological 0.956 0.923 – 0.991 0.0147 3624 23684 all phecode
341
Other demyelinating diseases of central nervous
Other demyelinating diseases of central nervous system
 Neurological 1 0.842 – 1.19 0.985 133 1330 all phecode
342 Hemiplegia Neurological 0.99 0.9 – 1.09 0.841 464 4607 all phecode
343 Infantile cerebral palsy Neurological 1.16 0.937 – 1.45 0.168 85 847 all phecode
344 Other paralytic syndromes Neurological 1.06 0.975 – 1.14 0.181 682 6808 all phecode
345 Epilepsy, recurrent seizures, convulsions Neurological 0.966 0.927 – 1.01 0.103 2553 25307 all phecode
345.1 Epilepsy Neurological 0.987 0.916 – 1.06 0.734 747 7465 all phecode
345.11 Generalized convulsive epilepsy Neurological 0.999 0.875 – 1.14 0.992 233 2330 all phecode
345.12 Partial epilepsy Neurological 1.03 0.941 – 1.12 0.543 534 5335 all phecode
345.3 Convulsions Neurological 0.97 0.93 – 1.01 0.162 2396 23796 all phecode
346
Abnormal findings on study of brain and/or
Abnormal findings on study of brain and/or nervous system
 Neurological 0.983 0.844 – 1.15 0.83 183 1824 all phecode
346.1
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of skull and head
 Neurological 0.984 0.932 – 1.04 0.546 1472 14587 all phecode
346.2
Nonspecific abnormal results of function study
Nonspecific abnormal results of function study of brain and central nervous system
 Neurological 0.981 0.815 – 1.18 0.839 120 1181 all phecode
346.3
Nonspecific abnormal findings in cerebrospinal
Nonspecific abnormal findings in cerebrospinal fluid
 Neurological 0.882 0.724 – 1.07 0.211 110 1100 all phecode
347 Cataplexy and narcolepsy Neurological 1.02 0.833 – 1.25 0.855 101 1010 all phecode
348 Other conditions of brain Neurological 0.998 0.95 – 1.05 0.93 1793 17894 all phecode
348.2 Cerebral edema and compression of brain Neurological 1 0.936 – 1.08 0.914 905 9034 all phecode
348.4 Cerebral cysts Neurological 0.96 0.836 – 1.1 0.565 229 2290 all phecode
348.7 Coma Neurological 0.968 0.844 – 1.11 0.641 229 2275 all phecode
348.8 Encephalopathy, not elsewhere classified Neurological 0.972 0.906 – 1.04 0.429 853 8479 all phecode
348.9 Other conditions of brain, NOS Neurological 0.976 0.935 – 1.02 0.27 2341 23287 all phecode
349
Other and unspecified disorders of the nervous
Other and unspecified disorders of the nervous system
 Neurological 0.991 0.927 – 1.06 0.804 941 9385 all phecode
350 Abnormal movement Neurological 1 0.976 – 1.03 0.892 6706 38762 all phecode
350.1 Abnormal involuntary movements Neurological 1.01 0.978 – 1.05 0.454 3273 30524 all phecode
350.2 Abnormality of gait Neurological 1 0.968 – 1.04 0.918 3920 30520 all phecode
350.3 Lack of coordination Neurological 0.997 0.935 – 1.06 0.919 1062 10554 all phecode
350.5 Abnormal reflex Neurological 0.887 0.766 – 1.03 0.107 200 1988 all phecode
350.6 Disturbances of sensation of smell and taste Neurological 1.04 0.955 – 1.14 0.35 558 5576 all phecode
351 Other peripheral nerve disorders Neurological 0.987 0.962 – 1.01 0.326 7401 34460 all phecode
352 Disorders of other cranial nerves Neurological 0.962 0.915 – 1.01 0.13 1714 17106 all phecode
352.1 Trigeminal nerve disorders [CN5] Neurological 1.03 0.937 – 1.12 0.576 535 5344 all phecode
352.2 Facial nerve disorders [CN7] Neurological 0.975 0.906 – 1.05 0.492 783 7826 all phecode
353 Nerve root and plexus disorders Neurological 0.957 0.926 – 0.988 0.00758 4256 33369 all phecode
353.1 Nerve plexus lesions Neurological 0.928 0.836 – 1.03 0.163 390 3900 all phecode
353.2 Nerve root lesions Neurological 0.986 0.825 – 1.18 0.876 130 1287 all phecode
355 Complex regional/central pain syndrome Neurological 0.965 0.882 – 1.06 0.444 531 5295 all phecode
355.1 Chronic pain syndrome Neurological 0.961 0.894 – 1.03 0.274 843 8386 all phecode
356 Hereditary and idiopathic peripheral neuropathy Neurological 0.983 0.941 – 1.03 0.43 2335 20731 all phecode
357 Inflammatory and toxic neuropathy Neurological 0.972 0.937 – 1.01 0.116 3472 29956 all phecode
358 Myoneural disorders Neurological 0.976 0.918 – 1.04 0.443 1147 11391 all phecode
358.1 Myasthenia gravis Neurological 1.09 0.896 – 1.32 0.398 109 1082 all phecode
359 Muscular dystrophies and other myopathies Neurological 0.979 0.92 – 1.04 0.511 1134 11274 all phecode
359.1 Muscular dystrophies Neurological 0.925 0.713 – 1.2 0.557 64 632 all phecode
359.2 Myopathy Neurological 0.982 0.922 – 1.05 0.584 1092 10843 all phecode
360 Disorders of the globe Sense Organs 0.908 0.758 – 1.09 0.299 131 1276 all phecode
360.2 Progressive myopia Sense Organs 0.814 0.631 – 1.05 0.115 65 640 all phecode
361 Retinal detachments and defects Sense Organs 0.96 0.889 – 1.04 0.29 733 7131 all phecode
361.1 Retinal detachment with retinal defect Sense Organs 0.954 0.848 – 1.07 0.44 302 2962 all phecode
362 Other retinal disorders Sense Organs 0.973 0.938 – 1.01 0.137 3569 22997 all phecode
362.2
Degeneration of macula and posterior pole of
Degeneration of macula and posterior pole of retina
 Sense Organs 0.997 0.952 – 1.04 0.901 2172 15483 all phecode
362.21 Macular degeneration, dry Sense Organs 1.11 1 – 1.23 0.0486 419 3438 all phecode
362.22 Macular degeneration, wet Sense Organs 1.1 0.923 – 1.31 0.283 148 1184 all phecode
362.23 Cystoid macular degeneration of retina Sense Organs 0.991 0.894 – 1.1 0.866 408 3839 all phecode
362.26 Macular puckering of retina Sense Organs 0.985 0.921 – 1.05 0.659 976 8610 all phecode
362.27 Drusen (degenerative) of retina Sense Organs 1.04 0.944 – 1.14 0.431 488 4558 all phecode
362.29 Macular degeneration (senile) of retina NOS Sense Organs 0.999 0.95 – 1.05 0.956 1883 13955 all phecode
362.3 Other nondiabetic retinopathy Sense Organs 0.981 0.917 – 1.05 0.586 976 8527 all phecode
362.31 Separation of retinal layers Sense Organs 0.995 0.898 – 1.1 0.918 413 4056 all phecode
362.4 Retinal vascular changes and abnomalities Sense Organs 1.04 0.961 – 1.13 0.306 662 5933 all phecode
362.6 Peripheral retinal degenerations Sense Organs 0.906 0.814 – 1.01 0.0698 392 3787 all phecode
362.7 Hereditary retinal dystrophies Sense Organs 1.02 0.884 – 1.17 0.802 215 2103 all phecode
362.8 Retinal hemorrhage/ischemia Sense Organs 0.956 0.836 – 1.09 0.507 241 2368 all phecode
362.9 Retinal edema Sense Organs 0.919 0.818 – 1.03 0.158 324 2936 all phecode
363
Chorioretinal inflammations, scars, and other
Chorioretinal inflammations, scars, and other disorders of choroid
 Sense Organs 0.975 0.888 – 1.07 0.59 492 4746 all phecode
363.3 Chorioretinal scars Sense Organs 1.02 0.912 – 1.14 0.712 332 3184 all phecode
364 Corneal opacity and other disorders of cornea Sense Organs 1.02 0.96 – 1.09 0.504 1132 10772 all phecode
364.1 Corneal opacity Sense Organs 0.944 0.85 – 1.05 0.276 394 3846 all phecode
364.2 Corneal edema Sense Organs 0.939 0.776 – 1.14 0.521 123 1208 all phecode
364.4 Corneal degenerations Sense Organs 1 0.904 – 1.11 0.994 402 3962 all phecode
364.41 Keratoconus Sense Organs 0.985 0.777 – 1.25 0.904 75 739 all phecode
364.5 Corneal dystrophy Sense Organs 1.04 0.949 – 1.14 0.385 502 4682 all phecode
364.51 Fuchs' dystrophy Sense Organs 1.06 0.93 – 1.2 0.388 266 2521 all phecode
364.9 Cornea replaced by transplant Sense Organs 0.953 0.759 – 1.2 0.681 91 885 all phecode
365 Glaucoma Sense Organs 0.995 0.956 – 1.04 0.828 2672 21326 all phecode
365.1 Open-angle glaucoma Sense Organs 1.02 0.94 – 1.1 0.678 705 6491 all phecode
365.11 Primary open angle glaucoma Sense Organs 1.01 0.909 – 1.11 0.903 403 3681 all phecode
365.2 Primary angle-closure glaucoma Sense Organs 1.02 0.896 – 1.17 0.741 251 2370 all phecode
366 Cataract Sense Organs 0.984 0.959 – 1.01 0.24 8611 28043 all phecode
366.1 Nonsenile Cataract Sense Organs 0.944 0.815 – 1.09 0.438 207 1979 all phecode
366.2 Senile cataract Sense Organs 0.984 0.953 – 1.01 0.301 5480 24980 all phecode
367
Disorders of refraction and accommodation
Disorders of refraction and accommodation; blindness and low vision
 Sense Organs 0.989 0.966 – 1.01 0.386 8967 37779 all phecode
367.1 Myopia Sense Organs 0.982 0.953 – 1.01 0.25 5014 34677 all phecode
367.2 Astigmatism Sense Organs 0.995 0.962 – 1.03 0.757 4161 32463 all phecode
367.8 Hypermetropia Sense Organs 0.997 0.952 – 1.04 0.893 2039 18599 all phecode
367.9 Blindness and low vision Sense Organs 0.987 0.931 – 1.05 0.65 1277 12356 all phecode
368 Visual disturbances Sense Organs 1.01 0.986 – 1.04 0.342 5715 39599 all phecode
368.1 Amblyopia Sense Organs 1.13 1.04 – 1.23 0.00328 651 6479 all phecode
368.2 Diplopia and disorders of binocular vision Sense Organs 0.982 0.922 – 1.05 0.569 1087 10786 all phecode
368.3 Anisometropia Sense Organs 1.07 0.929 – 1.22 0.365 219 2168 all phecode
368.4 Visual field defects Sense Organs 0.99 0.931 – 1.05 0.758 1132 11173 all phecode
368.9 Subjective visual disturbances Sense Organs 1.02 0.96 – 1.09 0.484 1070 10620 all phecode
368.91 Psychophysical visual disturbances Sense Organs 0.936 0.772 – 1.13 0.497 120 1171 all phecode
369 Infection of the eye Sense Organs 0.975 0.939 – 1.01 0.174 3185 28240 all phecode
369.2 Eye infection, viral Sense Organs 0.93 0.848 – 1.02 0.122 502 4954 all phecode
369.5 Conjunctivitis, infectious Sense Organs 0.988 0.949 – 1.03 0.54 2716 24970 all phecode
370 Keratitis Sense Organs 1.05 0.992 – 1.11 0.0924 1365 13169 all phecode
370.1 Corneal ulcer Sense Organs 1.01 0.876 – 1.16 0.923 223 2194 all phecode
370.2 Superficial keratitis Sense Organs 1.06 0.973 – 1.16 0.176 546 5393 all phecode
370.3 Keratoconjunctivitis Sense Organs 1.04 0.958 – 1.13 0.348 649 6263 all phecode
370.31 Keratoconjunctivitis sicca Sense Organs 0.949 0.814 – 1.11 0.502 179 1677 all phecode
371 Inflammation of the eye Sense Organs 0.984 0.953 – 1.02 0.326 4414 32310 all phecode
371.1 Uveitis, noninfectious or NOS Sense Organs 0.989 0.903 – 1.08 0.803 541 5278 all phecode
371.2 Conjunctivitis, noninfectious Sense Organs 1 0.937 – 1.08 0.917 906 8939 all phecode
371.21 Allergic conjunctivitis Sense Organs 0.998 0.926 – 1.08 0.954 756 7515 all phecode
371.3 Inflammation of eyelids Sense Organs 0.986 0.95 – 1.02 0.432 3398 26983 all phecode
371.33 Noninfectious dermatoses of eyelid Sense Organs 0.893 0.747 – 1.07 0.215 133 1291 all phecode
372 Disorders of conjunctiva Sense Organs 0.998 0.937 – 1.06 0.938 1118 10728 all phecode
374 Other disorders of eyelids Sense Organs 0.986 0.949 – 1.03 0.485 2940 24188 all phecode
374.1 Ectropion or entropion Sense Organs 1.03 0.927 – 1.13 0.628 431 4084 all phecode
374.2 Lagophthalmos Sense Organs 0.987 0.861 – 1.13 0.852 235 2335 all phecode
374.3 Ptosis of eyelid Sense Organs 0.973 0.914 – 1.04 0.391 1102 10734 all phecode
374.6 Dermatochalasis Sense Organs 0.977 0.916 – 1.04 0.475 1040 9720 all phecode
375 Disorders of lacrimal system Sense Organs 0.997 0.962 – 1.03 0.868 3694 26045 all phecode
375.1 Dry eyes Sense Organs 0.998 0.965 – 1.03 0.922 4040 26751 all phecode
375.2 Epiphora Sense Organs 0.986 0.893 – 1.09 0.776 442 4354 all phecode
376 Disorders of the orbit Sense Organs 1.06 0.946 – 1.18 0.324 352 3508 all phecode
377 Disorders of optic nerve and visual pathways Sense Organs 0.974 0.909 – 1.04 0.46 913 9021 all phecode
377.1 Optic atrophy Sense Organs 0.894 0.79 – 1.01 0.0744 283 2793 all phecode
377.3 Optic neuritis/neuropathy Sense Organs 1.01 0.929 – 1.11 0.761 585 5775 all phecode
378
Strabismus and other disorders of binocular eye
Strabismus and other disorders of binocular eye movements
 Sense Organs 1.04 0.982 – 1.1 0.179 1275 12460 all phecode
378.1 Strabismus (not specified as paralytic) Sense Organs 1.04 0.969 – 1.12 0.265 828 8130 all phecode
378.2 Nystagmus and other irregular eye movements Sense Organs 1.09 0.923 – 1.28 0.32 170 1686 all phecode
378.5 Paralytic strabismus Sense Organs 0.983 0.879 – 1.1 0.765 349 3437 all phecode
379 Other disorders of eye Sense Organs 0.997 0.967 – 1.03 0.871 5046 29999 all phecode
379.1 Scleritis and episcleritis Sense Organs 0.953 0.815 – 1.11 0.543 176 1743 all phecode
379.2 Disorders of vitreous body Sense Organs 1.01 0.975 – 1.05 0.557 3634 23186 all phecode
379.3 Aphakia and other disorders of lens Sense Organs 1 0.842 – 1.19 0.977 135 1258 all phecode
379.4 Anomalies of pupillary function Sense Organs 1.09 0.962 – 1.23 0.185 287 2833 all phecode
379.5 Disorders of iris and ciliary body Sense Organs 0.995 0.886 – 1.12 0.939 304 2948 all phecode
379.51 Pigmentary iris degeneration Sense Organs 1.03 0.816 – 1.31 0.78 77 731 all phecode
379.9 Pain, swelling or discharge of eye Sense Organs 0.976 0.918 – 1.04 0.448 1129 11130 all phecode
380 Disorders of external ear Sense Organs 1.01 0.969 – 1.06 0.577 2242 20393 all phecode
380.1 Otitis externa Sense Organs 0.948 0.898 – 1 0.057 1469 14580 all phecode
380.4 Impacted cerumen Sense Organs 1.04 1 – 1.09 0.0483 2648 23557 all phecode
381 Otitis media and Eustachian tube disorders Sense Organs 0.975 0.944 – 1.01 0.12 4255 36417 all phecode
381.1 Otitis media Sense Organs 0.97 0.934 – 1.01 0.109 3079 29813 all phecode
381.11 Suppurative and unspecified otitis media Sense Organs 0.968 0.93 – 1.01 0.122 2610 25602 all phecode
381.2 Eustachian tube disorders Sense Organs 0.982 0.934 – 1.03 0.46 1816 17827 all phecode
381.3 Mastoiditis & related conditions Sense Organs 0.965 0.82 – 1.14 0.667 153 1530 all phecode
381.9 Otorrhea Sense Organs 0.945 0.849 – 1.05 0.308 372 3713 all phecode
382 Otalgia Sense Organs 0.972 0.927 – 1.02 0.257 1884 18673 all phecode
383 Otosclerosis Sense Organs 1.03 0.855 – 1.24 0.756 124 1240 all phecode
384 Other disorders of tympanic membrane Sense Organs 0.902 0.825 – 0.988 0.0258 516 5156 all phecode
384.1 Myringitis Sense Organs 1.2 0.904 – 1.59 0.208 51 502 all phecode
384.4 Perforation of tympanic membrane Sense Organs 0.915 0.827 – 1.01 0.0849 403 4029 all phecode
385 Other disorders of middle ear and mastoid Sense Organs 0.974 0.882 – 1.08 0.6 432 4320 all phecode
385.3 Cholesteatoma Sense Organs 0.947 0.837 – 1.07 0.391 277 2770 all phecode
385.5
Tympanosclerosis and middle ear disease related
Tympanosclerosis and middle ear disease related to otitis media
 Sense Organs 1.09 0.906 – 1.32 0.352 118 1180 all phecode
386
Vertiginous syndromes and other disorders of
Vertiginous syndromes and other disorders of vestibular system
 Sense Organs 0.954 0.909 – 1 0.0546 1882 18186 all phecode
386.1 Meniere's disease Sense Organs 0.984 0.876 – 1.11 0.792 319 3156 all phecode
386.2 Peripheral or central vertigo Sense Organs 0.948 0.9 – 0.999 0.0467 1586 15423 all phecode
386.21 Central origin vertigo Sense Organs 0.941 0.886 – 0.999 0.0455 1208 11844 all phecode
386.3 Labyrinthitis Sense Organs 0.96 0.91 – 1.01 0.143 1482 14530 all phecode
386.9
Dizziness and giddiness (Light-headedness and
Dizziness and giddiness (Light-headedness and vertigo)
 Sense Organs 0.984 0.959 – 1.01 0.236 6933 38286 all phecode
388 Other disorders of ear Sense Organs 0.962 0.899 – 1.03 0.263 960 9501 all phecode
389 Hearing loss Sense Organs 0.978 0.954 – 1 0.0789 8182 38069 all phecode
389.1 Sensorineural hearing loss Sense Organs 1.01 0.973 – 1.04 0.739 4107 29258 all phecode
389.2 Conductive hearing loss Sense Organs 1.01 0.943 – 1.08 0.775 905 9042 all phecode
389.3 Degenerative and vascular disorders of ear Sense Organs 1.04 0.894 – 1.22 0.597 192 1808 all phecode
389.4 Tinnitus Sense Organs 0.981 0.938 – 1.02 0.38 2291 22130 all phecode
389.5 Disorders of acoustic nerve Sense Organs 0.981 0.821 – 1.17 0.832 124 1229 all phecode
394 Rheumatic disease of the heart valves Circulatory System 0.927 0.878 – 0.979 0.00651 1458 13732 all phecode
394.1 Mitral valve stenosis and aortic valve stenosis Circulatory System 0.854 0.765 – 0.953 0.00488 350 3415 all phecode
394.2 Mitral valve disease Circulatory System 0.885 0.803 – 0.976 0.0148 462 4560 all phecode
394.3 Aortic valve disease Circulatory System 1.02 0.87 – 1.19 0.84 176 1691 all phecode
394.4 Acute rheumatic heart disease Circulatory System 0.948 0.728 – 1.23 0.693 55 546 all phecode
394.7 Disease of tricuspid valve Circulatory System 0.947 0.869 – 1.03 0.214 587 5739 all phecode
395 Heart valve disorders Circulatory System 0.956 0.925 – 0.989 0.00993 3976 28748 all phecode
395.1 Nonrheumatic mitral valve disorders Circulatory System 0.94 0.899 – 0.983 0.00693 2175 20441 all phecode
395.2 Nonrheumatic aortic valve disorders Circulatory System 0.943 0.9 – 0.988 0.0134 2060 17194 all phecode
395.3 Nonrheumatic tricuspid valve disorders Circulatory System 0.962 0.876 – 1.06 0.418 493 4864 all phecode
395.4 Nonrheumatic pulmonary valve disorders Circulatory System 0.892 0.733 – 1.08 0.251 108 1080 all phecode
395.6 Heart valve replaced Circulatory System 0.952 0.896 – 1.01 0.114 1177 10833 all phecode
396 Abnormal heart sounds Circulatory System 0.981 0.951 – 1.01 0.224 4718 34395 all phecode
401 Hypertension Circulatory System 0.889 0.87 – 0.907 3.09e-28 23317 23367 all phecode
401.1 Essential hypertension Circulatory System 0.89 0.871 – 0.909 1.75e-27 23158 23364 all phecode
401.2 Hypertensive heart and/or renal disease Circulatory System 0.862 0.828 – 0.897 4.03e-13 3503 14616 all phecode
401.21 Hypertensive heart disease Circulatory System 0.879 0.819 – 0.945 0.000434 893 6607 all phecode
401.22 Hypertensive chronic kidney disease Circulatory System 0.859 0.822 – 0.899 3.58e-11 2584 13072 all phecode
401.3 Other hypertensive complications Circulatory System 0.872 0.836 – 0.91 3.77e-10 2679 15833 all phecode
411 Ischemic Heart Disease Circulatory System 0.878 0.855 – 0.9 1.92e-23 8807 30299 all phecode
411.1 Unstable angina (intermediate coronary syndrome) Circulatory System 0.815 0.761 – 0.873 5.43e-09 937 8574 all phecode
411.2 Myocardial infarction Circulatory System 0.849 0.819 – 0.881 2.41e-18 3594 21716 all phecode
411.3 Angina pectoris Circulatory System 0.853 0.817 – 0.891 5.44e-13 2485 18304 all phecode
411.4 Coronary atherosclerosis Circulatory System 0.869 0.846 – 0.894 2.01e-23 7555 27492 all phecode
411.41 Aneurysm and dissection of heart Circulatory System 0.79 0.669 – 0.934 0.00565 156 1529 all phecode
411.8
Other chronic ischemic heart disease
Other chronic ischemic heart disease, unspecified
 Circulatory System 0.851 0.827 – 0.877 1.08e-26 6331 25741 all phecode
411.9
Other acute and subacute forms of ischemic
Other acute and subacute forms of ischemic heart disease
 Circulatory System 0.871 0.787 – 0.964 0.00776 442 4211 all phecode
414 Other forms of chronic heart disease Circulatory System 0.919 0.885 – 0.955 1.79e-05 3101 22616 all phecode
414.2 ASCVD Circulatory System 0.916 0.847 – 0.99 0.0264 718 6816 all phecode
415 Pulmonary heart disease Circulatory System 0.953 0.919 – 0.988 0.00876 3366 30208 all phecode
415.1 Acute pulmonary heart disease Circulatory System 0.97 0.925 – 1.02 0.214 1912 19014 all phecode
415.11 Pulmonary embolism and infarction, acute Circulatory System 0.968 0.923 – 1.02 0.185 1906 18953 all phecode
415.2 Chronic pulmonary heart disease Circulatory System 0.932 0.888 – 0.979 0.0048 1808 17605 all phecode
415.21 Primary pulmonary hypertension Circulatory System 0.919 0.849 – 0.993 0.0333 706 7032 all phecode
416 Cardiomegaly Circulatory System 0.956 0.902 – 1.01 0.133 1254 12372 all phecode
418 Nonspecific chest pain Circulatory System 0.943 0.924 – 0.963 5.23e-08 12650 33952 all phecode
418.1 Precordial pain Circulatory System 0.895 0.848 – 0.946 7.01e-05 1471 13782 all phecode
420 Carditis Circulatory System 0.95 0.902 – 1 0.055 1588 15680 all phecode
420.1 Myocarditis Circulatory System 0.947 0.773 – 1.16 0.601 97 958 all phecode
420.2 Pericarditis Circulatory System 0.982 0.915 – 1.05 0.607 842 8402 all phecode
420.21 Acute pericarditis Circulatory System 1.02 0.879 – 1.19 0.757 177 1764 all phecode
420.22 Chronic pericarditis Circulatory System 0.966 0.797 – 1.17 0.726 117 1153 all phecode
420.3 Endocarditis Circulatory System 0.9 0.834 – 0.971 0.00641 764 7535 all phecode
425 Cardiomyopathy Circulatory System 0.942 0.9 – 0.987 0.011 2078 19881 all phecode
425.1 Primary/intrinsic cardiomyopathies Circulatory System 0.942 0.899 – 0.987 0.0126 1989 19025 all phecode
425.11 Hypertrophic obstructive cardiomyopathy Circulatory System 0.933 0.81 – 1.07 0.333 208 2050 all phecode
425.12 Other hypertrophic cardiomyopathy Circulatory System 0.909 0.788 – 1.05 0.189 201 1992 all phecode
425.2 Secondary/extrinsic cardiomyopathies Circulatory System 1.09 0.966 – 1.22 0.17 317 3170 all phecode
425.8 Other cardiomyopathy Circulatory System 0.807 0.657 – 0.993 0.0425 95 931 all phecode
426 Cardiac conduction disorders Circulatory System 0.953 0.931 – 0.975 5.31e-05 12327 25440 all phecode
426.2 Atrioventricular [AV] block Circulatory System 0.956 0.909 – 1 0.0765 1903 11501 all phecode
426.21 First degree AV block Circulatory System 0.961 0.905 – 1.02 0.192 1313 8899 all phecode
426.22 Mobitz II AV block Circulatory System 0.939 0.729 – 1.21 0.629 64 553 all phecode
426.23 Second degree AV block Circulatory System 1 0.871 – 1.16 0.956 216 1925 all phecode
426.24 Atrioventricular block, complete Circulatory System 0.935 0.848 – 1.03 0.176 461 3823 all phecode
426.25 Other heart block Circulatory System 0.982 0.848 – 1.14 0.807 203 1803 all phecode
426.3 Bundle branch block Circulatory System 0.986 0.942 – 1.03 0.544 2306 13999 all phecode
426.31 Right bundle branch block Circulatory System 1 0.946 – 1.06 0.967 1423 10758 all phecode
426.32 Left bundle branch block Circulatory System 0.957 0.895 – 1.02 0.203 969 8110 all phecode
426.4 Anomalous atrioventricular excitation Circulatory System 0.965 0.769 – 1.21 0.757 82 820 all phecode
426.7 Abnormal electrocardiogram [ECG] [EKG] Circulatory System 0.951 0.928 – 0.974 5.09e-05 10577 25186 all phecode
426.8 Other cardiac conduction disorders Circulatory System 0.899 0.831 – 0.974 0.00903 679 6650 all phecode
426.9 Cardiac pacemaker/device in situ Circulatory System 0.917 0.87 – 0.966 0.00105 1754 11536 all phecode
426.91 Cardiac pacemaker in situ Circulatory System 0.923 0.867 – 0.983 0.0124 1171 8184 all phecode
426.92 Cardiac defibrillator in situ Circulatory System 0.892 0.829 – 0.959 0.00207 846 7320 all phecode
427 Cardiac dysrhythmias Circulatory System 0.977 0.958 – 0.997 0.0248 17397 25735 all phecode
427.1 Paroxysmal tachycardia, unspecified Circulatory System 0.991 0.949 – 1.03 0.684 2474 18178 all phecode
427.11 Paroxysmal supraventricular tachycardia Circulatory System 0.981 0.93 – 1.03 0.463 1595 14293 all phecode
427.12 Paroxysmal ventricular tachycardia Circulatory System 0.979 0.921 – 1.04 0.503 1181 9915 all phecode
427.2 Atrial fibrillation and flutter Circulatory System 0.953 0.922 – 0.985 0.00404 5313 18688 all phecode
427.21 Atrial fibrillation Circulatory System 0.953 0.921 – 0.985 0.00453 5188 18409 all phecode
427.22 Atrial flutter Circulatory System 0.971 0.921 – 1.02 0.267 1693 11042 all phecode
427.3 Other specified cardiac dysrhythmias Circulatory System 0.984 0.959 – 1.01 0.204 8688 25552 all phecode
427.4 Cardiac arrest and ventricular fibrillation Circulatory System 0.981 0.896 – 1.07 0.674 536 5233 all phecode
427.41 Ventricular fibrillation and flutter Circulatory System 1.05 0.911 – 1.21 0.509 216 2118 all phecode
427.42 Cardiac arrest Circulatory System 0.931 0.84 – 1.03 0.175 410 4034 all phecode
427.5 Arrhythmia (cardiac) NOS Circulatory System 0.978 0.951 – 1.01 0.116 6905 25457 all phecode
427.6 Premature beats Circulatory System 0.968 0.926 – 1.01 0.145 2359 16248 all phecode
427.61 Supraventricular premature beats Circulatory System 0.978 0.902 – 1.06 0.585 670 6287 all phecode
427.7 Tachycardia NOS Circulatory System 0.951 0.922 – 0.98 0.00126 5124 25531 all phecode
427.8 Sinoatrial node dysfunction (Bradycardia) Circulatory System 0.966 0.901 – 1.04 0.331 912 7501 all phecode
427.9 Palpitations Circulatory System 0.985 0.953 – 1.02 0.357 4430 24505 all phecode
428 Congestive heart failure; nonhypertensive Circulatory System 0.884 0.855 – 0.915 1.4e-12 4300 23663 all phecode
428.1 Congestive heart failure (CHF) NOS Circulatory System 0.891 0.86 – 0.924 3.33e-10 3756 22446 all phecode
428.2 Heart failure NOS Circulatory System 0.881 0.85 – 0.914 9.38e-12 3701 21722 all phecode
428.3
Heart failure with reduced EF [Systolic or
Heart failure with reduced EF [Systolic or combined heart failure]
 Circulatory System 0.875 0.831 – 0.92 2.45e-07 1765 14476 all phecode
428.4
Heart failure with preserved EF [Diastolic
Heart failure with preserved EF [Diastolic heart failure]
 Circulatory System 0.884 0.839 – 0.932 3.95e-06 1648 13395 all phecode
429
Ill-defined descriptions and complications of
Ill-defined descriptions and complications of heart disease
 Circulatory System 0.948 0.928 – 0.969 1.27e-06 12635 32504 all phecode
429.1 Heart transplant/surgery Circulatory System 0.916 0.863 – 0.973 0.00422 1219 11696 all phecode
429.2 Abnormal function study of cardiovascular system Circulatory System 0.917 0.891 – 0.943 2.13e-09 6322 29232 all phecode
429.3 Symptoms involving cardiovascular system Circulatory System 0.954 0.932 – 0.977 9.54e-05 9650 32421 all phecode
429.9 Cardiac complications, not elsewhere classified Circulatory System 0.938 0.868 – 1.01 0.105 723 7072 all phecode
430 Intracranial hemorrhage Circulatory System 1.08 1 – 1.16 0.0487 789 7842 all phecode
430.1 Subarachnoid hemorrhage Circulatory System 1.01 0.885 – 1.15 0.893 261 2610 all phecode
430.2 Intracerebral hemorrhage Circulatory System 1.13 1.01 – 1.26 0.0262 368 3671 all phecode
430.3 Subdural hemorrhage Circulatory System 1.07 0.946 – 1.22 0.269 272 2680 all phecode
433 Cerebrovascular disease Circulatory System 0.951 0.923 – 0.979 0.000861 5463 32242 all phecode
433.1 Occlusion and stenosis of precerebral arteries Circulatory System 0.901 0.86 – 0.945 1.79e-05 1978 16212 all phecode
433.11
Occlusion of cerebral arteries, with cerebral
Occlusion of cerebral arteries, with cerebral infarction
 Circulatory System 0.887 0.781 – 1.01 0.0676 260 2517 all phecode
433.12 Cerebral atherosclerosis Circulatory System 0.87 0.686 – 1.1 0.249 80 789 all phecode
433.2 Occlusion of cerebral arteries Circulatory System 0.957 0.917 – 0.998 0.0409 2437 21732 all phecode
433.21
Cerebral artery occlusion, with cerebral
Cerebral artery occlusion, with cerebral infarction
 Circulatory System 0.959 0.919 – 1 0.0591 2357 21103 all phecode
433.3 Cerebral ischemia Circulatory System 0.972 0.934 – 1.01 0.166 2780 22868 all phecode
433.31 Transient cerebral ischemia Circulatory System 0.969 0.929 – 1.01 0.155 2409 20762 all phecode
433.5 Cerebral aneurysm Circulatory System 0.94 0.854 – 1.04 0.211 474 4724 all phecode
433.6 Acute, but ill-defined cerebrovascular disease Circulatory System 0.953 0.865 – 1.05 0.328 464 4518 all phecode
433.8 Late effects of cerebrovascular disease Circulatory System 0.963 0.89 – 1.04 0.341 695 6822 all phecode
440 Atherosclerosis Circulatory System 0.894 0.857 – 0.933 2.55e-07 2477 19724 all phecode
440.1 Atherosclerosis of renal artery Circulatory System 0.795 0.695 – 0.909 0.000795 231 2291 all phecode
440.2 Atherosclerosis of the extremities Circulatory System 0.89 0.843 – 0.94 2.5e-05 1516 13532 all phecode
440.21
Atherosclerosis of native arteries of the
Atherosclerosis of native arteries of the extremities with ulceration or gangrene
 Circulatory System 0.915 0.809 – 1.04 0.162 274 2669 all phecode
440.22
Atherosclerosis of native arteries of the
Atherosclerosis of native arteries of the extremities with intermittent claudication
 Circulatory System 0.913 0.855 – 0.974 0.00568 1040 9647 all phecode
440.9 Atherosclerosis of aorta Circulatory System 0.865 0.805 – 0.93 8.37e-05 846 8124 all phecode
441 Vascular insufficiency of intestine Circulatory System 0.859 0.783 – 0.941 0.00109 515 5115 all phecode
441.1 Acute vascular insufficiency of intestine Circulatory System 0.932 0.816 – 1.06 0.301 240 2387 all phecode
441.2 Chronic vascular insufficiency of intestine Circulatory System 0.705 0.596 – 0.835 5.12e-05 154 1536 all phecode
442 Other aneurysm Circulatory System 0.895 0.86 – 0.932 8.18e-08 2779 21466 all phecode
442.1 Aortic aneurysm Circulatory System 0.876 0.836 – 0.918 3.08e-08 2054 16492 all phecode
442.11 Abdominal aortic aneurysm Circulatory System 0.86 0.809 – 0.914 1.3e-06 1189 10558 all phecode
442.2 Aneurysm of iliac artery Circulatory System 0.948 0.817 – 1.1 0.479 202 2002 all phecode
442.3 Aneurysm of artery of lower extremity Circulatory System 0.881 0.75 – 1.03 0.122 179 1765 all phecode
442.4 Arterial dissection Circulatory System 0.994 0.856 – 1.16 0.942 184 1840 all phecode
442.8 Aneurysm of other specified artery Circulatory System 0.858 0.772 – 0.954 0.00446 399 3978 all phecode
443 Peripheral vascular disease Circulatory System 0.934 0.899 – 0.97 0.000449 3086 24814 all phecode
443.1 Raynaud's syndrome Circulatory System 1.09 1.01 – 1.18 0.0223 742 7390 all phecode
443.7
Peripheral angiopathy in diseases classified
Peripheral angiopathy in diseases classified elsewhere
 Circulatory System 0.906 0.785 – 1.04 0.172 220 2087 all phecode
443.8 Other specified peripheral vascular diseases Circulatory System 0.929 0.891 – 0.969 0.000555 2557 21985 all phecode
443.9 Peripheral vascular disease, unspecified Circulatory System 0.895 0.857 – 0.935 7.8e-07 2341 18862 all phecode
444 Arterial embolism and thrombosis Circulatory System 0.909 0.845 – 0.977 0.00971 848 8423 all phecode
444.1
Arterial embolism and thrombosis of lower
Arterial embolism and thrombosis of lower extremity artery
 Circulatory System 0.892 0.792 – 1 0.0583 313 3099 all phecode
444.2 Embolism and thrombosis of abdominal aorta Circulatory System 0.862 0.727 – 1.02 0.085 155 1548 all phecode
446 Polyarteritis nodosa and allied conditions Circulatory System 0.964 0.876 – 1.06 0.458 460 4559 all phecode
446.4 Wegener's granulomatosis Circulatory System 1.06 0.871 – 1.28 0.571 109 1075 all phecode
446.5 Giant cell arteritis Circulatory System 1 0.796 – 1.27 0.976 79 749 all phecode
446.9 Arteritis NOS Circulatory System 0.912 0.809 – 1.03 0.129 289 2876 all phecode
447 Other disorders of arteries and arterioles Circulatory System 0.895 0.859 – 0.932 1.03e-07 2647 22765 all phecode
447.1 Stricture of artery Circulatory System 0.793 0.723 – 0.87 8.58e-07 523 5163 all phecode
447.7 Aortic ectasia Circulatory System 0.952 0.884 – 1.02 0.187 804 7938 all phecode
448 Disease of capillaries Circulatory System 1.01 0.953 – 1.07 0.707 1237 12127 all phecode
450 Noninfectious disorders of lymphatic channels Circulatory System 1.03 0.984 – 1.08 0.201 2104 20985 all phecode
451 Phlebitis and thrombophlebitis Circulatory System 1.02 0.943 – 1.1 0.655 738 7355 all phecode
451.2
Phlebitis and thrombophlebitis of lower
Phlebitis and thrombophlebitis of lower extremities
 Circulatory System 1.16 1.02 – 1.32 0.0279 244 2437 all phecode
452 Other venous embolism and thrombosis Circulatory System 0.962 0.933 – 0.992 0.0133 4957 29867 all phecode
452.1 Iatrogenic pulmonary embolism and infarction Circulatory System 0.87 0.768 – 0.985 0.0284 276 2747 all phecode
452.2 Deep vein thrombosis [DVT] Circulatory System 0.972 0.937 – 1.01 0.128 3260 26940 all phecode
452.8 Postphlebitic syndrome Circulatory System 1.15 0.969 – 1.36 0.109 154 1529 all phecode
453 Chronic venous hypertension Circulatory System 0.884 0.768 – 1.02 0.0875 220 2168 all phecode
454 Varicose veins Circulatory System 0.98 0.942 – 1.02 0.322 2827 24555 all phecode
454.1 Varicose veins of lower extremity Circulatory System 0.983 0.942 – 1.03 0.42 2469 21426 all phecode
454.11 Varicose veins of lower extremity, symptomtic Circulatory System 0.981 0.93 – 1.03 0.473 1565 15056 all phecode
455 Hemorrhoids Circulatory System 0.989 0.961 – 1.02 0.472 5799 29818 all phecode
456 Chronic venous insufficiency [CVI] Circulatory System 0.984 0.947 – 1.02 0.409 3097 24898 all phecode
457
Encounter for long-term (current) use of
Encounter for long-term (current) use of anticoagulants, antithrombotics, aspirin
 Circulatory System 0.917 0.875 – 0.961 0.000263 2095 15309 all phecode
457.2
Encounter for long-term (current) use of
Encounter for long-term (current) use of antiplatelets/antithrombotics
 Circulatory System 0.935 0.833 – 1.05 0.258 324 3221 all phecode
457.3 Encounter for long-term (current) use of aspirin Circulatory System 0.911 0.868 – 0.956 0.00014 1973 14689 all phecode
458 Hypotension Circulatory System 0.94 0.912 – 0.969 6.15e-05 5091 32185 all phecode
458.1 Orthostatic hypotension Circulatory System 0.955 0.902 – 1.01 0.11 1344 12938 all phecode
458.2 Iatrogenic hypotension Circulatory System 0.925 0.87 – 0.984 0.0139 1109 11012 all phecode
458.9 Hypotension NOS Circulatory System 0.935 0.906 – 0.965 3.1e-05 4618 31186 all phecode
459 Other disorders of circulatory system Circulatory System 0.951 0.927 – 0.976 0.000116 7825 34792 all phecode
459.1 Hemorrhage NOS Circulatory System 0.964 0.897 – 1.04 0.318 834 8215 all phecode
459.7 Blood vessel replaced Circulatory System 0.937 0.884 – 0.993 0.0271 1305 13023 all phecode
459.9 Circulatory disease NEC Circulatory System 0.953 0.927 – 0.979 0.000462 6706 33592 all phecode
464 Acute sinusitis Respiratory 0.997 0.967 – 1.03 0.856 4792 32137 all phecode
465
Acute upper respiratory infections of multiple
Acute upper respiratory infections of multiple or unspecified sites
 Respiratory 0.996 0.974 – 1.02 0.762 9601 35915 all phecode
465.2 Acute pharyngitis Respiratory 1.01 0.978 – 1.04 0.61 5310 32365 all phecode
465.4 Acute laryngitis and tracheitis Respiratory 0.999 0.905 – 1.1 0.989 443 4428 all phecode
470 Septal Deviations/Turbinate Hypertrophy Respiratory 1.01 0.959 – 1.06 0.77 1797 17640 all phecode
471 Nasal polyps Respiratory 1.11 1.02 – 1.21 0.0125 592 5881 all phecode
472 Chronic pharyngitis and nasopharyngitis Respiratory 1.03 0.976 – 1.08 0.323 1797 16986 all phecode
473 Diseases of the larynx and vocal cords Respiratory 0.976 0.94 – 1.01 0.225 2983 25244 all phecode
473.1 Chronic laryngitis Respiratory 0.995 0.784 – 1.26 0.966 68 674 all phecode
473.3 Paralysis/spasm of vocal cords or larynx Respiratory 0.961 0.885 – 1.04 0.355 628 6254 all phecode
473.4 Voice disturbance Respiratory 0.979 0.937 – 1.02 0.324 2336 21975 all phecode
474 Acute and chronic tonsillitis Respiratory 0.948 0.883 – 1.02 0.142 880 7892 all phecode
474.1 Acute tonsillitis Respiratory 0.951 0.846 – 1.07 0.396 335 3181 all phecode
474.2 Chronic tonsillitis and adenoiditis Respiratory 0.948 0.875 – 1.03 0.185 700 6445 all phecode
475 Chronic sinusitis Respiratory 1.01 0.973 – 1.04 0.738 4378 27891 all phecode
475.9 Postnasal drip Respiratory 1.04 0.972 – 1.11 0.256 922 9017 all phecode
476 Allergic rhinitis Respiratory 1 0.98 – 1.02 0.9 12687 28117 all phecode
477 Epistaxis or throat hemorrhage Respiratory 0.959 0.902 – 1.02 0.177 1150 11318 all phecode
478 Throat pain Respiratory 0.986 0.89 – 1.09 0.784 426 4195 all phecode
479 Other upper respiratory disease Respiratory 0.999 0.971 – 1.03 0.961 5627 28048 all phecode
480 Pneumonia Respiratory 0.975 0.948 – 1 0.0701 5947 37034 all phecode
480.1 Bacterial pneumonia Respiratory 1.01 0.952 – 1.08 0.7 1155 11495 all phecode
480.11 Pneumococcal pneumonia Respiratory 0.941 0.862 – 1.03 0.168 568 5644 all phecode
480.12 Pseudomonal pneumonia Respiratory 1.11 0.936 – 1.32 0.225 153 1523 all phecode
480.13 MRSA pneumonia Respiratory 1.13 0.93 – 1.36 0.224 117 1165 all phecode
480.2 Viral pneumonia Respiratory 0.945 0.818 – 1.09 0.442 202 1992 all phecode
480.3 Pneumonia due to fungus (mycoses) Respiratory 0.974 0.826 – 1.15 0.756 159 1590 all phecode
480.5 Bronchopneumonia and lung abscess Respiratory 0.955 0.798 – 1.14 0.612 135 1312 all phecode
481 Influenza Respiratory 0.985 0.93 – 1.04 0.599 1355 13284 all phecode
483 Acute bronchitis and bronchiolitis Respiratory 0.966 0.932 – 1 0.0621 3412 29871 all phecode
495 Asthma Respiratory 0.983 0.96 – 1.01 0.168 8671 33569 all phecode
495.1 Chronic obstructive asthma Respiratory 0.927 0.836 – 1.03 0.151 397 3925 all phecode
495.11 Chronic obstructive asthma with exacerbation Respiratory 1.2 0.956 – 1.5 0.116 81 802 all phecode
495.2 Asthma with exacerbation Respiratory 1.05 0.996 – 1.11 0.0689 1629 16033 all phecode
496 Chronic airway obstruction Respiratory 0.95 0.922 – 0.979 0.000831 5343 28343 all phecode
496.1 Emphysema Respiratory 0.967 0.924 – 1.01 0.145 2134 19414 all phecode
496.2 Chronic bronchitis Respiratory 0.94 0.909 – 0.972 0.00028 4128 26624 all phecode
496.21 Obstructive chronic bronchitis Respiratory 0.945 0.912 – 0.978 0.0014 3747 25467 all phecode
496.3 Bronchiectasis Respiratory 0.988 0.905 – 1.08 0.791 549 5453 all phecode
497 Bronchitis Respiratory 0.963 0.919 – 1.01 0.117 1946 18824 all phecode
498 Acute bronchospasm Respiratory 1.03 0.943 – 1.13 0.475 496 4943 all phecode
499 Cystic fibrosis Respiratory 1.08 0.911 – 1.27 0.389 151 1510 all phecode
500 Lung disease due to external agents Respiratory 1.04 0.954 – 1.14 0.367 557 5551 all phecode
500.1 Extrinsic allergic alveolitis Respiratory 1.19 0.961 – 1.48 0.109 92 920 all phecode
500.2 Pneumoconiosis Respiratory 0.917 0.733 – 1.15 0.448 78 764 all phecode
501 Pneumonitis due to inhalation of food or vomitus Respiratory 0.956 0.881 – 1.04 0.287 634 6225 all phecode
502 Postinflammatory pulmonary fibrosis Respiratory 1.01 0.939 – 1.09 0.784 815 8076 all phecode
503 Pulmonary congestion and hypostasis Respiratory 0.875 0.814 – 0.941 3e-04 835 8243 all phecode
504 Other alveolar and parietoalveolar pneumonopathy Respiratory 1 0.918 – 1.09 0.998 595 5878 all phecode
504.1 Idiopathic fibrosing alveolitis Respiratory 0.982 0.872 – 1.1 0.758 311 3084 all phecode
505 Other pulmonary inflamation or edema Respiratory 0.91 0.864 – 0.957 0.00029 1638 15749 all phecode
506 Empyema and pneumothorax Respiratory 0.975 0.938 – 1.01 0.204 2894 25235 all phecode
507 Pleurisy; pleural effusion Respiratory 0.975 0.938 – 1.01 0.207 2916 26208 all phecode
508
Pulmonary collapse; interstitial and
Pulmonary collapse; interstitial and compensatory emphysema
 Respiratory 0.984 0.943 – 1.03 0.463 2382 22588 all phecode
509 Respiratory failure, insufficiency, arrest Respiratory 0.945 0.914 – 0.977 0.000992 4032 29477 all phecode
509.1 Respiratory failure Respiratory 0.93 0.887 – 0.975 0.00262 1937 18949 all phecode
509.2 Respiratory insufficiency Respiratory 0.979 0.921 – 1.04 0.482 1174 11679 all phecode
509.3
Pulmonary insufficiency or respiratory failure
Pulmonary insufficiency or respiratory failure following trauma and surgery
 Respiratory 0.95 0.904 – 1 0.048 1689 16489 all phecode
509.8
Dependence on respirator [Ventilator] or
Dependence on respirator [Ventilator] or supplemental oxygen
 Respiratory 0.959 0.912 – 1.01 0.101 1741 17249 all phecode
510 Other diseases of lung Respiratory 0.981 0.953 – 1.01 0.199 5503 35907 all phecode
510.2 Lung transplant Respiratory 1.01 0.862 – 1.17 0.944 176 1757 all phecode
512 Other symptoms of respiratory system Respiratory 0.97 0.952 – 0.989 0.00196 18621 28154 all phecode
512.1 Wheezing Respiratory 0.966 0.914 – 1.02 0.222 1409 13516 all phecode
512.2 Painful respiration Respiratory 0.992 0.949 – 1.04 0.71 2309 21263 all phecode
512.3 Abnormal chest sounds Respiratory 0.968 0.858 – 1.09 0.6 291 2845 all phecode
512.7 Shortness of breath Respiratory 0.961 0.939 – 0.984 0.00104 10034 28081 all phecode
512.8 Cough Respiratory 0.961 0.938 – 0.984 0.00118 9501 28148 all phecode
512.9 Other dyspnea Respiratory 0.968 0.946 – 0.99 0.00504 10804 28104 all phecode
513 Respiratory abnormalities Respiratory 0.97 0.95 – 0.99 0.00368 12932 33822 all phecode
513.3 Hypoventilation Respiratory 0.95 0.886 – 1.02 0.156 880 8646 all phecode
513.31 Apnea Respiratory 0.996 0.904 – 1.1 0.94 462 4607 all phecode
513.32 Orthopnea Respiratory 0.815 0.711 – 0.935 0.00347 220 2160 all phecode
513.4 Hyperventilation Respiratory 1.04 0.945 – 1.14 0.451 515 5124 all phecode
513.8 Disorders of diaphragm Respiratory 0.99 0.869 – 1.13 0.885 258 2557 all phecode
514 Abnormal findings examination of lungs Respiratory 0.989 0.96 – 1.02 0.46 5365 34834 all phecode
514.1
Abnormal results of function study of pulmonary
Abnormal results of function study of pulmonary system
 Respiratory 1.02 0.893 – 1.16 0.812 258 2580 all phecode
514.2 Solitary pulmonary nodule Respiratory 1 0.964 – 1.04 0.929 3018 27338 all phecode
516 Abnormal sputum Respiratory 0.943 0.873 – 1.02 0.136 735 7332 all phecode
516.1 Hemoptysis Respiratory 0.918 0.843 – 0.998 0.0451 611 6080 all phecode
519
Other diseases of respiratory system, not
Other diseases of respiratory system, not elsewhere classified
 Respiratory 0.966 0.94 – 0.993 0.0123 6458 39057 all phecode
519.1 Tracheostomy complications Respiratory 1.01 0.871 – 1.16 0.937 214 2136 all phecode
519.2 Respiratory complications Respiratory 0.936 0.848 – 1.03 0.187 445 4430 all phecode
519.8 Other diseases of respiratory system, NEC Respiratory 0.969 0.92 – 1.02 0.237 1588 15787 all phecode
519.9
Symptoms involving respiratory system and other
Symptoms involving respiratory system and other chest symptoms
 Respiratory 0.97 0.941 – 1 0.0564 4706 34489 all phecode
520 Disorders of tooth development Digestive 0.981 0.879 – 1.09 0.725 369 3690 all phecode
520.1 Hereditary disturbances in tooth structure Digestive 1.05 0.886 – 1.23 0.597 165 1642 all phecode
520.2 Disturbances in tooth eruption Digestive 0.921 0.8 – 1.06 0.255 218 2172 all phecode
521 Diseases of hard tissues of teeth Digestive 0.933 0.87 – 1 0.049 898 8954 all phecode
521.1 Dental caries Digestive 0.94 0.875 – 1.01 0.0915 837 8349 all phecode
521.2 Dental abrasion, erosion and attrition Digestive 0.964 0.735 – 1.26 0.788 52 510 all phecode
522 Diseases of pulp and periapical tissues Digestive 0.954 0.874 – 1.04 0.286 535 5340 all phecode
522.5 Periapical abscess Digestive 0.957 0.87 – 1.05 0.36 459 4583 all phecode
523 Gingival and periodontal diseases Digestive 1.02 0.944 – 1.1 0.62 718 7180 all phecode
523.1 Gingivitis Digestive 1.15 0.961 – 1.37 0.13 142 1418 all phecode
523.3 Periodontitis (acute or chronic) Digestive 0.991 0.891 – 1.1 0.864 364 3636 all phecode
523.31 Acute periodontitis Digestive 0.98 0.872 – 1.1 0.729 311 3109 all phecode
523.32 Chronic periodontitis Digestive 1.06 0.882 – 1.27 0.538 122 1204 all phecode
524 Dentofacial anomalies, including malocclusion Digestive 0.941 0.844 – 1.05 0.272 363 3630 all phecode
524.3 Anomalies of tooth position/malocclusion Digestive 0.951 0.828 – 1.09 0.478 220 2200 all phecode
525
Other diseases of the teeth and supporting
Other diseases of the teeth and supporting structures
 Digestive 0.974 0.913 – 1.04 0.424 1039 10382 all phecode
525.1 Loss of teeth or edentulism Digestive 1.01 0.905 – 1.12 0.905 374 3731 all phecode
526 Diseases of the jaws Digestive 1.01 0.967 – 1.05 0.729 2680 26455 all phecode
526.1 Cysts of the jaws Digestive 0.979 0.859 – 1.12 0.753 247 2470 all phecode
526.3 Anomalies of jaw size/symmetry Digestive 1.03 0.9 – 1.17 0.682 241 2383 all phecode
526.4 Temporomandibular joint disorders Digestive 1.02 0.963 – 1.07 0.562 1504 15025 all phecode
526.41 Temporomandibular joint disorder, unspecified Digestive 0.996 0.937 – 1.06 0.896 1187 11858 all phecode
526.42 Arthralgia/ankylosis of temporomandibular joint Digestive 1.05 0.972 – 1.13 0.216 741 7400 all phecode
526.5 Inflammatory conditions of jaw Digestive 1.14 1.01 – 1.29 0.0384 287 2864 all phecode
526.8 Exostosis of jaw Digestive 1.27 0.954 – 1.68 0.102 53 521 all phecode
526.9 Jaw disease NOS Digestive 1.07 0.973 – 1.18 0.159 487 4867 all phecode
527 Diseases of the salivary glands Digestive 1.01 0.958 – 1.06 0.789 1781 17771 all phecode
527.1 Hypertrophy of salivary gland Digestive 0.971 0.744 – 1.27 0.83 58 579 all phecode
527.2 Sialoadenitis Digestive 0.986 0.888 – 1.1 0.791 394 3936 all phecode
527.7 Disturbance of salivary secretion Digestive 1.03 0.959 – 1.1 0.466 952 9481 all phecode
527.8 Other specified diseases of the salivary glands Digestive 1 0.879 – 1.15 0.947 254 2540 all phecode
528
Diseases of the oral soft tissues, excluding
Diseases of the oral soft tissues, excluding lesions specific for gingiva and tongue
 Digestive 1.04 0.996 – 1.08 0.0761 2643 26197 all phecode
528.1 Stomatitis and mucositis Digestive 0.979 0.903 – 1.06 0.605 668 6657 all phecode
528.11 Stomatitis and mucositis (ulcerative) Digestive 1.03 0.897 – 1.19 0.656 211 2110 all phecode
528.12 Oral aphthae Digestive 0.925 0.801 – 1.07 0.283 215 2137 all phecode
528.3 Cellulitis and abscess of oral soft tissues Digestive 1.15 1 – 1.32 0.0476 235 2338 all phecode
528.4 Cysts of oral soft tissues Digestive 1.04 0.862 – 1.26 0.666 124 1229 all phecode
528.41 Cyst of the salivary gland Digestive 1.07 0.844 – 1.36 0.563 77 760 all phecode
528.5 Diseases of lips Digestive 1.04 0.944 – 1.15 0.426 462 4602 all phecode
528.6 Leukoplakia of oral mucosa Digestive 1.04 0.874 – 1.24 0.653 137 1370 all phecode
528.7 Sialolithiasis Digestive 0.966 0.821 – 1.14 0.677 163 1623 all phecode
529 Diseases and other conditions of the tongue Digestive 0.948 0.876 – 1.03 0.182 690 6878 all phecode
529.1 Glossitis Digestive 0.942 0.786 – 1.13 0.521 129 1281 all phecode
529.6 Glossodynia Digestive 0.917 0.785 – 1.07 0.276 168 1652 all phecode
530 Diseases of esophagus Digestive 0.973 0.954 – 0.992 0.00673 17081 27931 all phecode
530.1 Esophagitis, GERD and related diseases Digestive 0.971 0.952 – 0.991 0.00427 16572 27931 all phecode
530.11 GERD Digestive 0.969 0.95 – 0.989 0.00212 16143 27929 all phecode
530.12 Ulcer of esophagus Digestive 1.01 0.907 – 1.12 0.906 400 3983 all phecode
530.13 Barrett's esophagus Digestive 1 0.928 – 1.08 0.994 762 7584 all phecode
530.14 Reflux esophagitis Digestive 0.987 0.941 – 1.04 0.587 1900 17495 all phecode
530.15 Eosinophilic esophagitis Digestive 1.08 0.935 – 1.24 0.309 221 2210 all phecode
530.2 Esophageal bleeding (varices/hemorrhage) Digestive 0.91 0.839 – 0.987 0.0228 651 6473 all phecode
530.3 Stricture and stenosis of esophagus Digestive 0.991 0.925 – 1.06 0.802 911 8971 all phecode
530.5 Disorders of esophageal motility Digestive 1.04 0.949 – 1.13 0.428 548 5432 all phecode
530.6 Diverticulum of esophagus, acquired Digestive 1.15 0.962 – 1.37 0.125 129 1265 all phecode
530.7 Gastroesophageal laceration-hemorrhage syndrome Digestive 1.2 0.963 – 1.5 0.105 82 812 all phecode
530.9 Heartburn Digestive 0.944 0.895 – 0.996 0.036 1519 14928 all phecode
531 Peptic ulcer (excl. esophageal) Digestive 0.982 0.939 – 1.03 0.447 2073 20617 all phecode
531.1 Hemorrhage from gastrointestinal ulcer Digestive 1.01 0.912 – 1.12 0.817 391 3883 all phecode
531.2 Gastric ulcer Digestive 1.01 0.951 – 1.07 0.749 1201 11970 all phecode
531.3 Duodenal ulcer Digestive 1.04 0.945 – 1.15 0.418 467 4640 all phecode
531.4 Peptic ulcer, site unspecified Digestive 0.97 0.902 – 1.04 0.411 804 8018 all phecode
531.5 Gastrojejunal ulcer Digestive 0.961 0.811 – 1.14 0.649 150 1500 all phecode
532 Dysphagia Digestive 0.979 0.951 – 1.01 0.171 5585 26852 all phecode
535 Gastritis and duodenitis Digestive 0.987 0.949 – 1.03 0.512 2799 27335 all phecode
535.1 Acute gastritis Digestive 1.02 0.965 – 1.09 0.432 1178 11750 all phecode
535.2 Atrophic gastritis Digestive 0.97 0.868 – 1.09 0.598 344 3413 all phecode
535.6 Duodenitis Digestive 1.02 0.91 – 1.14 0.727 334 3337 all phecode
535.8 Other specified gastritis Digestive 1 0.923 – 1.09 0.976 638 6354 all phecode
535.9 Gastritis and duodenitis, NOS Digestive 0.953 0.898 – 1.01 0.105 1255 12511 all phecode
536 Disorders of function of stomach Digestive 0.995 0.957 – 1.03 0.78 2911 27685 all phecode
536.3 Gastroparesis Digestive 0.999 0.925 – 1.08 0.984 706 6901 all phecode
536.7
Complications of gastrostomy, colostomy and
Complications of gastrostomy, colostomy and enterostomy
 Digestive 0.894 0.807 – 0.99 0.0315 407 4059 all phecode
536.8
Dyspepsia and other specified disorders of
Dyspepsia and other specified disorders of function of stomach
 Digestive 1.01 0.968 – 1.06 0.604 2150 21094 all phecode
537 Other disorders of stomach and duodenum Digestive 0.987 0.951 – 1.02 0.475 3183 30048 all phecode
537.1 Lesions of stomach and duodenum Digestive 0.962 0.825 – 1.12 0.618 173 1725 all phecode
539 Bariatric surgery Digestive 0.906 0.859 – 0.956 0.000307 1509 15074 all phecode
540 Appendiceal conditions Digestive 0.972 0.886 – 1.07 0.553 495 4948 all phecode
540.1 Appendicitis Digestive 0.989 0.895 – 1.09 0.826 425 4239 all phecode
540.11 Acute appendicitis Digestive 0.972 0.871 – 1.08 0.607 353 3511 all phecode
550 Abdominal hernia Digestive 0.991 0.965 – 1.02 0.517 6768 37731 all phecode
550.1 Inguinal hernia Digestive 1.04 0.986 – 1.09 0.154 1744 16488 all phecode
550.2 Diaphragmatic hernia Digestive 0.97 0.933 – 1.01 0.135 2817 25849 all phecode
550.3 Femoral hernia Digestive 0.963 0.801 – 1.16 0.692 131 1291 all phecode
550.4 Umbilical hernia Digestive 0.999 0.943 – 1.06 0.978 1313 13110 all phecode
550.5 Ventral hernia Digestive 0.945 0.905 – 0.988 0.0117 2241 22163 all phecode
550.6 Incisional hernia Digestive 0.938 0.885 – 0.993 0.0283 1313 13111 all phecode
555
Inflammatory bowel disease and other
Inflammatory bowel disease and other gastroenteritis and colitis
 Digestive 1.01 0.954 – 1.06 0.828 1536 15153 all phecode
555.1 Regional enteritis Digestive 0.996 0.929 – 1.07 0.904 919 9095 all phecode
555.2 Ulcerative colitis Digestive 1.04 0.975 – 1.12 0.22 937 9315 all phecode
555.21 Ulcerative colitis (chronic) Digestive 1.07 0.982 – 1.18 0.118 537 5315 all phecode
556 Ulceration of the lower GI tract Digestive 0.942 0.867 – 1.02 0.155 632 6267 all phecode
556.1 Ulceration of intestine Digestive 0.958 0.877 – 1.05 0.342 551 5451 all phecode
556.11
Angiodysplasia of intestine (without mention of
Angiodysplasia of intestine (without mention of hemorrhage)
 Digestive 1.01 0.873 – 1.16 0.941 214 2093 all phecode
557 Intestinal malabsorption (non-celiac) Digestive 0.955 0.908 – 1 0.0711 1716 16490 all phecode
557.1 Celiac disease Digestive 0.972 0.878 – 1.08 0.589 421 4026 all phecode
558 Noninfectious gastroenteritis Digestive 0.941 0.908 – 0.976 0.000949 3458 26408 all phecode
559 Ileostomy status Digestive 0.962 0.899 – 1.03 0.264 957 9565 all phecode
560 Intestinal obstruction without mention of hernia Digestive 0.987 0.95 – 1.03 0.497 3004 24851 all phecode
560.1 Paralytic ileus Digestive 1 0.951 – 1.05 0.975 1627 15714 all phecode
560.2 Impaction of intestine Digestive 0.934 0.84 – 1.04 0.205 387 3779 all phecode
560.3 Peritoneal or intestinal adhesions Digestive 0.957 0.845 – 1.08 0.492 266 2647 all phecode
560.4 Other intestinal obstruction Digestive 0.986 0.937 – 1.04 0.599 1651 16170 all phecode
561 Symptoms involving digestive system Digestive 0.982 0.942 – 1.02 0.379 2608 21766 all phecode
562 Diverticulosis and diverticulitis Digestive 1 0.975 – 1.03 0.826 6295 23431 all phecode
562.1 Diverticulosis Digestive 1 0.975 – 1.03 0.811 6246 23383 all phecode
562.2 Diverticulitis Digestive 0.986 0.936 – 1.04 0.597 1611 15162 all phecode
564 Functional digestive disorders Digestive 0.987 0.965 – 1.01 0.256 11411 28676 all phecode
564.1 Irritable Bowel Syndrome Digestive 0.976 0.941 – 1.01 0.188 3457 22266 all phecode
564.9 Personal history of diseases of digestive system Digestive 0.98 0.943 – 1.02 0.29 3074 25861 all phecode
565 Anal and rectal conditions Digestive 0.992 0.957 – 1.03 0.668 3355 30757 all phecode
565.1 Anal and rectal polyp Digestive 0.985 0.93 – 1.04 0.596 1305 12649 all phecode
567 Peritonitis and retroperitoneal infections Digestive 0.916 0.865 – 0.969 0.00219 1364 13616 all phecode
568 Other disorders of peritoneum Digestive 0.962 0.915 – 1.01 0.128 1705 17038 all phecode
568.1
Peritoneal adhesions (postoperative)
Peritoneal adhesions (postoperative) (postinfection)
 Digestive 0.965 0.91 – 1.02 0.235 1247 12468 all phecode
569 Other disorders of intestine Digestive 0.986 0.961 – 1.01 0.251 8079 35231 all phecode
569.1 Toxic gastroenteritis and colitis Digestive 0.895 0.797 – 1 0.0601 326 3260 all phecode
569.2 Gastrointestinal complications Digestive 0.949 0.898 – 1 0.0612 1395 13933 all phecode
571 Chronic liver disease and cirrhosis Digestive 0.901 0.873 – 0.93 9.75e-11 4610 32562 all phecode
571.5 Other chronic nonalcoholic liver disease Digestive 0.902 0.874 – 0.932 4.87e-10 4342 32234 all phecode
571.51 Cirrhosis of liver without mention of alcohol Digestive 0.853 0.8 – 0.911 1.74e-06 1018 10095 all phecode
571.6 Primary biliary cirrhosis Digestive 1.05 0.899 – 1.23 0.53 179 1790 all phecode
571.8
Liver abscess and sequelae of chronic liver
Liver abscess and sequelae of chronic liver disease
 Digestive 0.879 0.822 – 0.941 0.000207 950 9498 all phecode
571.81 Portal hypertension Digestive 0.898 0.823 – 0.979 0.0151 573 5730 all phecode
572 Ascites (non malignant) Digestive 0.966 0.925 – 1.01 0.124 2278 22675 all phecode
573 Other disorders of liver Digestive 0.923 0.896 – 0.95 4.89e-08 5599 33620 all phecode
573.1 Chronic passive congestion of liver Digestive 0.774 0.648 – 0.924 0.00463 136 1359 all phecode
573.2 Liver replaced by transplant Digestive 0.92 0.816 – 1.04 0.174 292 2920 all phecode
573.3 Hepatomegaly Digestive 0.873 0.793 – 0.961 0.00543 470 4700 all phecode
573.4 Acute and subacute necrosis of liver Digestive 0.899 0.799 – 1.01 0.0773 316 3149 all phecode
573.5 Jaundice (not of newborn) Digestive 0.925 0.864 – 0.989 0.0232 958 9496 all phecode
573.6
Nonspecific elevation of levels of transaminase
Nonspecific elevation of levels of transaminase or lactic acid dehydrogenase [LDH]
 Digestive 0.944 0.907 – 0.983 0.0051 2756 26470 all phecode
573.7 Abnormal results of function study of liver Digestive 0.935 0.9 – 0.972 0.000598 3018 27774 all phecode
573.9 Abnormal serum enzyme levels Digestive 0.934 0.905 – 0.964 1.76e-05 4679 33866 all phecode
574 Cholelithiasis and cholecystitis Digestive 0.997 0.961 – 1.03 0.869 3177 30809 all phecode
574.1 Cholelithiasis Digestive 1 0.965 – 1.04 0.889 2924 28874 all phecode
574.11 Cholelithiasis with acute cholecystitis Digestive 1.1 0.983 – 1.23 0.096 342 3412 all phecode
574.12 Cholelithiasis with other cholecystitis Digestive 1.08 0.985 – 1.18 0.106 553 5501 all phecode
574.2 Calculus of bile duct Digestive 1.01 0.939 – 1.08 0.809 852 8503 all phecode
574.3 Cholecystitis without cholelithiasis Digestive 0.996 0.926 – 1.07 0.905 822 8181 all phecode
575 Other biliary tract disease Digestive 1 0.957 – 1.04 0.994 2266 22555 all phecode
575.1 Cholangitis Digestive 1.01 0.905 – 1.13 0.836 354 3530 all phecode
575.2 Obstruction of bile duct Digestive 0.975 0.896 – 1.06 0.554 621 6201 all phecode
575.6 Cholesterolosis of gallbladder Digestive 0.901 0.781 – 1.04 0.153 207 2063 all phecode
575.7 Other disorders of gallbladder Digestive 1.04 0.973 – 1.11 0.247 939 9382 all phecode
575.8 Other disorders of biliary tract Digestive 0.966 0.909 – 1.03 0.274 1154 11523 all phecode
575.9
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of biliary tract
 Digestive 1.04 0.912 – 1.18 0.588 260 2600 all phecode
577 Diseases of pancreas Digestive 0.95 0.909 – 0.993 0.0237 2225 22106 all phecode
577.1 Acute pancreatitis Digestive 0.912 0.859 – 0.968 0.00239 1212 12110 all phecode
577.2 Chronic pancreatitis Digestive 0.915 0.833 – 1 0.0619 495 4950 all phecode
577.3 Cyst and pseudocyst of pancreas Digestive 0.931 0.852 – 1.02 0.117 570 5601 all phecode
578 Gastrointestinal hemorrhage Digestive 0.973 0.943 – 1 0.0836 4554 37045 all phecode
578.1 Hematemesis Digestive 0.971 0.883 – 1.07 0.545 485 4842 all phecode
578.2 Blood in stool Digestive 0.958 0.92 – 0.997 0.0334 2743 26554 all phecode
578.8 Hemorrhage of rectum and anus Digestive 0.993 0.95 – 1.04 0.746 2210 21750 all phecode
578.9 Hemorrhage of gastrointestinal tract Digestive 0.995 0.944 – 1.05 0.839 1562 15345 all phecode
579 Other symptoms involving abdomen and pelvis Digestive 0.988 0.957 – 1.02 0.452 4431 34209 all phecode
579.2 Splenomegaly Digestive 0.887 0.822 – 0.958 0.0022 730 7262 all phecode
579.8 Nonspecific abnormal findings in stool contents Digestive 1.01 0.951 – 1.06 0.851 1410 13877 all phecode
580 Nephritis; nephrosis; renal sclerosis Genitourinary 0.884 0.842 – 0.929 9.85e-07 1881 15516 all phecode
580.1 Glomerulonephritis Genitourinary 0.97 0.875 – 1.08 0.565 401 3992 all phecode
580.11 Proliferative glomerulonephritis Genitourinary 0.943 0.795 – 1.12 0.495 146 1440 all phecode
580.12 Non-proliferative glomerulonephritis Genitourinary 1.01 0.837 – 1.23 0.882 114 1128 all phecode
580.13 Acute glomerulonephritis, NOS Genitourinary 0.885 0.686 – 1.14 0.347 61 600 all phecode
580.14 Chronic glomerulonephritis, NOS Genitourinary 0.966 0.855 – 1.09 0.583 277 2760 all phecode
580.2
Nephrotic syndrome without mention of
Nephrotic syndrome without mention of glomerulonephritis
 Genitourinary 0.92 0.806 – 1.05 0.218 221 2193 all phecode
580.3
Nephritis and nephropathy without mention of
Nephritis and nephropathy without mention of glomerulonephritis
 Genitourinary 0.873 0.826 – 0.923 1.6e-06 1502 11930 all phecode
580.31
Nephritis and nephropathy in diseases
Nephritis and nephropathy in diseases classified elsewhere
 Genitourinary 0.852 0.796 – 0.913 4.54e-06 992 7228 all phecode
580.32
Nephritis and nephropathy with pathological
Nephritis and nephropathy with pathological lesion
 Genitourinary 0.927 0.857 – 1 0.0626 683 6612 all phecode
580.4 Renal sclerosis, NOS Genitourinary 0.977 0.876 – 1.09 0.683 340 3400 all phecode
585 Renal failure Genitourinary 0.914 0.891 – 0.939 3.03e-11 7470 32340 all phecode
585.1 Acute renal failure Genitourinary 0.903 0.874 – 0.934 1.86e-09 4265 27230 all phecode
585.2 Renal failure NOS Genitourinary 0.934 0.869 – 1 0.0591 832 8162 all phecode
585.3 Chronic renal failure [CKD] Genitourinary 0.917 0.89 – 0.945 1.4e-08 5580 29470 all phecode
585.31 Renal dialysis Genitourinary 0.916 0.849 – 0.988 0.0233 747 7423 all phecode
585.32 End stage renal disease Genitourinary 0.894 0.838 – 0.955 0.000839 1007 9783 all phecode
585.33 Chronic Kidney Disease, Stage III Genitourinary 0.91 0.875 – 0.945 1.29e-06 3209 21312 all phecode
585.34 Chronic Kidney Disease, Stage IV Genitourinary 0.883 0.827 – 0.944 0.000263 977 9190 all phecode
585.4 Chronic kidney disease, Stage I or II Genitourinary 0.908 0.855 – 0.965 0.00178 1227 11191 all phecode
586 Other disorders of the kidney and ureters Genitourinary 0.946 0.922 – 0.97 2.01e-05 7628 34189 all phecode
586.1 Anatomical abnormatilies of kidney and ureters Genitourinary 0.938 0.84 – 1.05 0.257 349 3480 all phecode
586.11 Small kidney Genitourinary 0.909 0.79 – 1.05 0.186 210 2093 all phecode
586.12 Vesicoureteral reflux Genitourinary 0.891 0.746 – 1.06 0.202 136 1360 all phecode
586.2 Cyst of kidney, acquired Genitourinary 0.935 0.883 – 0.99 0.0203 1381 12912 all phecode
586.3 Vascular disorders of kidney/hypertrophy Genitourinary 0.915 0.787 – 1.06 0.246 187 1862 all phecode
586.4 Stricture/obstruction of ureter Genitourinary 0.952 0.906 – 1 0.0483 1821 17115 all phecode
587 Kidney replaced by transpant Genitourinary 0.974 0.906 – 1.05 0.478 819 8134 all phecode
588 Disorders resulting from impaired renal function Genitourinary 0.928 0.868 – 0.991 0.0268 976 9389 all phecode
588.1 Renal osteodystrophy Genitourinary 0.996 0.882 – 1.13 0.951 290 2900 all phecode
588.2 Secondary hyperparathyroidism (of renal origin) Genitourinary 0.946 0.877 – 1.02 0.151 755 7275 all phecode
589 Abnormal results of function study of kidney Genitourinary 0.904 0.846 – 0.965 0.00258 1007 9834 all phecode
590 Pyelonephritis Genitourinary 0.948 0.898 – 1 0.0556 1461 14350 all phecode
591 Urinary tract infection Genitourinary 0.985 0.963 – 1.01 0.22 9873 32513 all phecode
592 Cystitis and urethritis Genitourinary 0.974 0.937 – 1.01 0.181 3038 24207 all phecode
592.1 Cystitis Genitourinary 0.972 0.935 – 1.01 0.162 2880 23279 all phecode
592.11 Acute cystitis Genitourinary 0.965 0.918 – 1.01 0.155 1783 16452 all phecode
592.12 Chronic cystitis Genitourinary 0.871 0.76 – 0.997 0.0452 239 2343 all phecode
592.13 Chronic interstitial cystitis Genitourinary 0.891 0.806 – 0.984 0.0233 431 4310 all phecode
592.2 Urethritis and urethral syndrome Genitourinary 1.03 0.889 – 1.18 0.734 210 2093 all phecode
593 Hematuria Genitourinary 0.974 0.944 – 1 0.0909 4859 32063 all phecode
593.1 Gross hematuria Genitourinary 0.949 0.9 – 1 0.0512 1585 14824 all phecode
593.2 Microscopic hematuria Genitourinary 0.952 0.892 – 1.02 0.139 1049 10301 all phecode
594 Urinary calculus Genitourinary 0.98 0.955 – 1.01 0.139 6707 38209 all phecode
594.1 Calculus of kidney Genitourinary 0.978 0.952 – 1.01 0.113 6273 38051 all phecode
594.2 Calculus of lower urinary tract Genitourinary 0.929 0.833 – 1.04 0.184 366 3638 all phecode
594.3 Calculus of ureter Genitourinary 0.989 0.935 – 1.05 0.692 1361 13561 all phecode
594.8 Renal colic Genitourinary 0.984 0.883 – 1.1 0.773 356 3560 all phecode
595 Hydronephrosis Genitourinary 0.988 0.939 – 1.04 0.648 1670 16658 all phecode
596 Other disorders of bladder Genitourinary 1 0.966 – 1.04 0.885 3074 28020 all phecode
596.1 Bladder neck obstruction Genitourinary 0.987 0.888 – 1.1 0.812 400 3942 all phecode
596.5 Functional disorders of bladder Genitourinary 1.01 0.956 – 1.06 0.834 1719 17049 all phecode
597 Other disorders of urethra and urinary tract Genitourinary 0.983 0.926 – 1.04 0.572 1211 11998 all phecode
597.1 Urethral stricture (not specified as infectious) Genitourinary 1.02 0.938 – 1.11 0.668 661 6537 all phecode
597.2 Urinary complications NEC Genitourinary 1.01 0.945 – 1.07 0.812 1049 10479 all phecode
597.8 Urethral hypermobility/ISD Genitourinary 0.913 0.787 – 1.06 0.228 189 1873 all phecode
598 Abnormal findings on examination of urine Genitourinary 0.992 0.831 – 1.18 0.926 138 1356 all phecode
598.4 Other cells and casts in urine Genitourinary 0.965 0.799 – 1.17 0.712 122 1192 all phecode
599 Other symptoms/disorders or the urinary system Genitourinary 0.988 0.968 – 1.01 0.256 14168 30681 all phecode
599.1 Urinary obstruction Genitourinary 1.01 0.939 – 1.1 0.718 728 6861 all phecode
599.2 Retention of urine Genitourinary 1 0.972 – 1.03 0.876 5034 28305 all phecode
599.3 Dysuria Genitourinary 0.991 0.96 – 1.02 0.589 4397 27849 all phecode
599.4 Urinary incontinence Genitourinary 0.976 0.947 – 1.01 0.106 5599 26960 all phecode
599.5 Frequency of urination and polyuria Genitourinary 0.994 0.965 – 1.02 0.706 5498 28723 all phecode
599.6 Oliguria and anuria Genitourinary 0.923 0.849 – 1 0.064 599 5902 all phecode
599.7 Urethral discharge Genitourinary 1.09 0.905 – 1.32 0.355 118 1175 all phecode
599.8 Other symptoms involving urinary system Genitourinary 0.976 0.947 – 1.01 0.113 5446 27963 all phecode
599.9 Other abnormality of urination Genitourinary 1 0.967 – 1.04 0.807 3041 24877 all phecode
600 Hyperplasia of prostate Genitourinary 1.02 0.98 – 1.06 0.346 4063 11364 all phecode
601 Inflammatory diseases of prostate Genitourinary 0.978 0.916 – 1.04 0.494 1044 9665 all phecode
601.1 Prostatitis Genitourinary 1 0.911 – 1.11 0.935 477 4596 all phecode
601.11 Acute prostatitis Genitourinary 1.16 0.961 – 1.4 0.124 124 1200 all phecode
601.12 Chronic prostatitis Genitourinary 0.967 0.778 – 1.2 0.765 95 943 all phecode
601.3 Orchitis and epididymitis Genitourinary 0.989 0.89 – 1.1 0.839 389 3822 all phecode
601.4 Balanoposthitis Genitourinary 0.886 0.741 – 1.06 0.181 127 1224 all phecode
601.8
Other inflammatory disorders of male genital
Other inflammatory disorders of male genital organs
 Genitourinary 0.898 0.763 – 1.06 0.192 161 1591 all phecode
602 Other disorders of prostate Genitourinary 1.09 0.973 – 1.21 0.143 361 3399 all phecode
602.3 Dysplasia of prostate Genitourinary 1.07 0.837 – 1.36 0.606 77 730 all phecode
603 Other disorders of testis Genitourinary 0.963 0.872 – 1.06 0.458 440 4354 all phecode
603.1 Hydrocele Genitourinary 1.01 0.893 – 1.14 0.892 293 2882 all phecode
603.2 Spermatocele Genitourinary 0.947 0.801 – 1.12 0.526 156 1539 all phecode
604 Disorders of penis Genitourinary 1.05 0.972 – 1.14 0.208 685 6748 all phecode
604.1 Redundant prepuce and phimosis/BXO Genitourinary 1.01 0.855 – 1.2 0.871 155 1540 all phecode
604.3 Peyronie's disease Genitourinary 1.06 0.922 – 1.23 0.398 215 2132 all phecode
605 Erectile dysfunction [ED] Genitourinary 0.984 0.947 – 1.02 0.391 3776 12700 all phecode
608 Other disorders of male genital organs Genitourinary 0.994 0.943 – 1.05 0.809 1645 13758 all phecode
609 Male infertility and abnormal spermatozoa Genitourinary 1.11 1.01 – 1.23 0.0389 424 4196 all phecode
609.1 Infertility, male Genitourinary 1.11 0.986 – 1.26 0.0847 302 2992 all phecode
609.11 Azoospermia and oligospermia Genitourinary 0.956 0.776 – 1.18 0.671 95 950 all phecode
609.2 Abnormal spermatozoa Genitourinary 1.18 0.994 – 1.4 0.0591 154 1519 all phecode
610 Benign mammary dysplasias Genitourinary 1.01 0.976 – 1.05 0.498 3683 16548 all phecode
610.1 Cystic mastopathy Genitourinary 1.03 0.976 – 1.08 0.301 1633 14191 all phecode
610.2 Fibroadenosis of breast Genitourinary 0.879 0.673 – 1.15 0.344 60 600 all phecode
610.4 Benign neoplasm of breast Genitourinary 0.998 0.958 – 1.04 0.912 2837 16430 all phecode
610.8 Other specified benign mammary dysplasias Genitourinary 1.04 0.976 – 1.1 0.242 1269 12191 all phecode
611 Abnormal findings on mammogram or breast exam Genitourinary 1.03 1 – 1.07 0.0306 6067 18690 all phecode
611.1 Abnormal mammogram Genitourinary 1.04 1 – 1.07 0.0362 4980 16120 all phecode
611.11 Mammographic microcalcification Genitourinary 1.03 0.963 – 1.09 0.434 1122 10394 all phecode
611.3 Lump or mass in breast Genitourinary 1.03 0.994 – 1.07 0.0966 3549 18572 all phecode
612
Breast conditions, congenital or relating to
Breast conditions, congenital or relating to hormones
 Genitourinary 1.01 0.944 – 1.07 0.827 1051 10425 all phecode
612.1 Galactorrhea Genitourinary 1.1 0.921 – 1.32 0.292 139 1390 all phecode
612.2 Hypertrophy of breast (Gynecomastia) Genitourinary 0.974 0.905 – 1.05 0.491 800 7962 all phecode
612.3 Congenital anomalies of breast Genitourinary 1.25 0.988 – 1.59 0.0626 83 810 all phecode
613 Other nonmalignant breast conditions Genitourinary 1 0.966 – 1.04 0.995 3897 22072 all phecode
613.1 Inflammatory disease of breast Genitourinary 1.02 0.933 – 1.11 0.718 593 5874 all phecode
613.5 Mastodynia Genitourinary 1 0.951 – 1.05 0.97 1675 16203 all phecode
613.7 Other signs and symptoms in breast Genitourinary 1.02 0.953 – 1.1 0.541 883 8754 all phecode
613.8 Other specified disorders of breast Genitourinary 1.02 0.955 – 1.09 0.534 932 9248 all phecode
613.9 Breast disorder NOS Genitourinary 0.992 0.939 – 1.05 0.761 1465 14174 all phecode
614 Inflammatory diseases of female pelvic organs Genitourinary 1 0.969 – 1.04 0.793 3715 19647 all phecode
614.1
Pelvic peritoneal adhesions, female
Pelvic peritoneal adhesions, female (postoperative) (postinfection)
 Genitourinary 0.979 0.876 – 1.09 0.708 337 3370 all phecode
614.3 Pelvic inflammatory disease (PID) Genitourinary 0.927 0.843 – 1.02 0.118 478 4773 all phecode
614.31 Acute inflammatory pelvic disease Genitourinary 1.07 0.862 – 1.32 0.556 94 933 all phecode
614.32 Chronic inflammatory pelvic disease Genitourinary 0.957 0.823 – 1.11 0.568 186 1842 all phecode
614.33 Pelvic inflammatory disease, NOS Genitourinary 0.941 0.825 – 1.07 0.364 246 2460 all phecode
614.4 Inflammatory diseases of uterus, except cervix Genitourinary 0.916 0.778 – 1.08 0.295 165 1639 all phecode
614.5
Inflammatory disease of cervix, vagina, and
Inflammatory disease of cervix, vagina, and vulva
 Genitourinary 1.01 0.97 – 1.05 0.704 3180 19539 all phecode
614.51 Cervicitis and endocervicitis Genitourinary 0.993 0.876 – 1.13 0.918 264 2640 all phecode
614.52 Vaginitis and vulvovaginitis Genitourinary 1.01 0.968 – 1.05 0.68 2732 18924 all phecode
614.53 Cyst or abscess of Bartholin's gland Genitourinary 1 0.835 – 1.2 0.992 132 1311 all phecode
614.54 Abscess or ulceration of vulva Genitourinary 1.06 0.923 – 1.22 0.406 225 2244 all phecode
615 Endometriosis Genitourinary 0.995 0.944 – 1.05 0.838 1585 14666 all phecode
618 Genital prolapse Genitourinary 1.01 0.96 – 1.05 0.831 2079 17915 all phecode
618.1 Prolapse of vaginal walls Genitourinary 1 0.947 – 1.06 0.97 1408 13456 all phecode
618.2 Uterine/Uterovaginal prolapse Genitourinary 0.983 0.899 – 1.07 0.699 542 5390 all phecode
618.5 Prolapse of vaginal vault after hysterectomy Genitourinary 0.993 0.883 – 1.12 0.902 317 3162 all phecode
618.6 Vaginal enterocele, congenital or acquired Genitourinary 1.08 0.979 – 1.19 0.125 441 4394 all phecode
619 Noninflammatory female genital disorders Genitourinary 1 0.971 – 1.03 0.978 5728 18687 all phecode
619.1
Noninflammatory disorders of ovary, fallopian
Noninflammatory disorders of ovary, fallopian tube, and broad ligament
 Genitourinary 0.959 0.903 – 1.02 0.168 1233 12082 all phecode
619.2 Disorders of uterus, NEC Genitourinary 0.924 0.848 – 1.01 0.0735 591 5897 all phecode
619.3 Noninflammatory disorders of cervix Genitourinary 1.03 0.937 – 1.13 0.542 483 4823 all phecode
619.4 Noninflammatory disorders of vagina Genitourinary 1.02 0.979 – 1.07 0.326 2525 18404 all phecode
619.5 Noninflammatory disorders of vulva and perineum Genitourinary 1.02 0.958 – 1.08 0.57 1189 11717 all phecode
620 Dysplasia of female genital organs Genitourinary 1.04 0.932 – 1.15 0.519 395 3950 all phecode
620.1 Dysplasia of cervix Genitourinary 1.07 0.916 – 1.25 0.394 178 1780 all phecode
621 Endometrial hyperplasia Genitourinary 0.978 0.885 – 1.08 0.663 437 4370 all phecode
622 Polyp of female genital organs Genitourinary 1.03 0.978 – 1.09 0.247 1449 14264 all phecode
622.1 Polyp of corpus uteri Genitourinary 1 0.94 – 1.06 0.998 1132 11189 all phecode
622.2 Mucous polyp of cervix Genitourinary 1.13 1.02 – 1.25 0.0168 445 4444 all phecode
623 Hypertrophy of female genital organs Genitourinary 1.05 0.972 – 1.12 0.235 824 8165 all phecode
624 Symptoms involving female genital tract Genitourinary 1.01 0.955 – 1.07 0.692 1348 12518 all phecode
624.1 Dystrophy of female genital tract Genitourinary 0.931 0.809 – 1.07 0.312 216 2155 all phecode
624.2 Atrophy of female genital tract Genitourinary 1.08 0.847 – 1.38 0.53 64 615 all phecode
624.9 stress incontinence, female Genitourinary 1.02 0.969 – 1.07 0.515 1935 15408 all phecode
625
Pain and other symptoms associated with female
Pain and other symptoms associated with female genital organs
 Genitourinary 0.988 0.958 – 1.02 0.446 5653 17303 all phecode
625.1 Dyspareunia Genitourinary 0.993 0.937 – 1.05 0.823 1267 12474 all phecode
626
Disorders of menstruation and other abnormal
Disorders of menstruation and other abnormal bleeding from female genital tract
 Genitourinary 0.991 0.961 – 1.02 0.584 5940 15585 all phecode
626.1 Irregular menstrual cycle/bleeding Genitourinary 0.995 0.961 – 1.03 0.79 4315 14604 all phecode
626.11 Absent or infrequent menstruation Genitourinary 1.02 0.959 – 1.09 0.482 1062 8531 all phecode
626.12 Excessive or frequent menstruation Genitourinary 0.969 0.924 – 1.02 0.194 2097 11991 all phecode
626.13 Irregular menstrual cycle Genitourinary 0.982 0.935 – 1.03 0.478 1957 12265 all phecode
626.14 Irregular menstrual bleeding Genitourinary 0.975 0.911 – 1.04 0.461 970 8996 all phecode
626.15 Infertility, female, associated with anovulation Genitourinary 0.996 0.895 – 1.11 0.947 394 3789 all phecode
626.2 Dysmenorrhea Genitourinary 0.982 0.927 – 1.04 0.548 1373 9857 all phecode
626.4 Premenstrual tension syndromes Genitourinary 0.992 0.884 – 1.11 0.888 336 3308 all phecode
626.8 Infertility, female Genitourinary 0.985 0.915 – 1.06 0.697 817 6741 all phecode
627 Menopausal and postmenopausal disorders Genitourinary 1.01 0.981 – 1.05 0.408 4560 14557 all phecode
627.1 Postmenopausal bleeding Genitourinary 1.04 0.979 – 1.11 0.197 1146 10338 all phecode
627.2 Symptomatic menopause Genitourinary 1.01 0.968 – 1.05 0.707 3017 13763 all phecode
627.21 Symptomatic artificial menopause Genitourinary 1.04 0.881 – 1.22 0.659 152 1514 all phecode
627.22
Need for Hormone replacement therapy
Need for Hormone replacement therapy (postmenopausal)
 Genitourinary 0.992 0.89 – 1.1 0.877 356 3513 all phecode
627.3 Postmenopausal atrophic vaginitis Genitourinary 1.04 0.971 – 1.11 0.279 997 9484 all phecode
627.4 Premenopausal menorrhagia Genitourinary 0.968 0.868 – 1.08 0.564 361 3580 all phecode
627.5 Premature menopause and other ovarian failure Genitourinary 1.1 0.978 – 1.23 0.114 309 3082 all phecode
628 Ovarian cyst Genitourinary 0.979 0.932 – 1.03 0.386 1945 13838 all phecode
634 Miscarriage; stillbirth Pregnancy Complications 1.03 0.956 – 1.11 0.462 826 8047 all phecode
634.1 Missed abortion/Hydatidiform mole Pregnancy Complications 1.1 0.972 – 1.25 0.129 273 2715 all phecode
634.3 Ectopic pregnancy Pregnancy Complications 1 0.832 – 1.2 0.996 117 1170 all phecode
635
Hemorrhage during pregnancy; childbirth and
Hemorrhage during pregnancy; childbirth and postpartum
 Pregnancy Complications 1.1 1.01 – 1.2 0.031 563 5309 all phecode
635.2
Antepartum hemorrhage, abruptio placentae, and
Antepartum hemorrhage, abruptio placentae, and placenta previa
 Pregnancy Complications 1.07 0.959 – 1.19 0.231 370 3629 all phecode
635.3 Placenta previa and abruptio placenta Pregnancy Complications 1.17 1.03 – 1.32 0.0159 288 2850 all phecode
636
Early or threatened labor; hemorrhage in early
Early or threatened labor; hemorrhage in early pregnancy
 Pregnancy Complications 1.06 0.989 – 1.13 0.106 1080 7870 all phecode
636.1 Threatened premature labor Pregnancy Complications 0.992 0.89 – 1.11 0.882 380 3799 all phecode
636.2 Early onset of delivery Pregnancy Complications 0.991 0.876 – 1.12 0.88 288 2868 all phecode
636.3 Hemorrhage in early pregnancy Pregnancy Complications 1.04 0.944 – 1.15 0.412 441 4365 all phecode
636.8 Cervical incompetence Pregnancy Complications 0.971 0.767 – 1.23 0.806 77 770 all phecode
637
Short gestation; low birth weight; and fetal
Short gestation; low birth weight; and fetal growth retardation
 Pregnancy Complications 0.943 0.755 – 1.18 0.606 85 850 all phecode
642
Hypertension complicating pregnancy
Hypertension complicating pregnancy, childbirth, and the puerperium
 Pregnancy Complications 0.961 0.881 – 1.05 0.369 585 5725 all phecode
642.1 Preeclampsia and eclampsia Pregnancy Complications 0.978 0.866 – 1.1 0.718 302 3013 all phecode
643 Excessive vomiting in pregnancy Pregnancy Complications 0.961 0.841 – 1.1 0.556 252 2506 all phecode
643.1 Hyperemesis gravidarum Pregnancy Complications 0.887 0.729 – 1.08 0.231 119 1190 all phecode
644 Anemia during pregnancy Pregnancy Complications 1.12 0.97 – 1.29 0.125 224 2224 all phecode
646 Other complications of pregnancy NEC Pregnancy Complications 1.03 0.959 – 1.11 0.409 855 6531 all phecode
647
Infectious and parasitic complications
Infectious and parasitic complications affecting pregnancy
 Pregnancy Complications 1.17 1.01 – 1.35 0.0349 211 2093 all phecode
647.1
Infections of genitourinary tract during
Infections of genitourinary tract during pregnancy
 Pregnancy Complications 1.08 0.94 – 1.25 0.268 222 2213 all phecode
647.3 Major puerperal infection Pregnancy Complications 1.03 0.794 – 1.34 0.818 65 650 all phecode
649
Other conditions or status of the mother
Other conditions or status of the mother complicating pregnancy, childbirth, or the puerperium
 Pregnancy Complications 1.03 0.967 – 1.09 0.376 1275 8010 all phecode
649.1
Diabetes or abnormal glucose tolerance
Diabetes or abnormal glucose tolerance complicating pregnancy
 Pregnancy Complications 0.97 0.892 – 1.06 0.479 649 5687 all phecode
653
Problems associated with amniotic cavity and
Problems associated with amniotic cavity and membranes
 Pregnancy Complications 1.12 1.03 – 1.22 0.0101 587 5463 all phecode
654.1
Abnormality of organs and soft tissues of
Abnormality of organs and soft tissues of pelvis complicating pregnancy, childbirth, or the puerperium
 Pregnancy Complications 1.08 0.939 – 1.25 0.272 207 2055 all phecode
654.2 Rhesus isoimmunization in pregnancy Pregnancy Complications 1.06 0.916 – 1.23 0.427 204 2040 all phecode
655
Known or suspected fetal abnormality affecting
Known or suspected fetal abnormality affecting management of mother
 Pregnancy Complications 1.03 0.975 – 1.09 0.298 1624 10064 all phecode
655.1 Abnormality in fetal heart rate or rhythm Pregnancy Complications 1.06 0.975 – 1.16 0.166 616 5533 all phecode
656 Other perinatal conditions of fetus or newborn Pregnancy Complications 1.03 0.963 – 1.11 0.354 898 7014 all phecode
656.2 Respiratory conditions of fetus and newborn Pregnancy Complications 1.1 0.85 – 1.43 0.459 66 660 all phecode
669 Complications of labor and delivery NEC Pregnancy Complications 1.03 0.96 – 1.11 0.401 887 6802 all phecode
671
Venous/cerebrovascular complications embolism
Venous/cerebrovascular complications embolism in pregnancy and the puerperium
 Pregnancy Complications 0.909 0.792 – 1.04 0.171 236 2351 all phecode
674 Other complications of the puerperium NEC Pregnancy Complications 1.21 1.02 – 1.43 0.0296 158 1580 all phecode
676
Other disorders of the breast associated with
Other disorders of the breast associated with childbirth and disorders of lactation
 Pregnancy Complications 0.995 0.853 – 1.16 0.947 184 1814 all phecode
681 Superficial cellulitis and abscess Dermatologic 0.963 0.937 – 0.989 0.00597 6500 38394 all phecode
681.1 Cellulitis and abscess of fingers/toes Dermatologic 0.915 0.862 – 0.971 0.00335 1256 11462 all phecode
681.2 Cellulitis and abscess of face/neck Dermatologic 0.996 0.932 – 1.06 0.902 1007 9981 all phecode
681.3 Cellulitis and abscess of arm/hand Dermatologic 0.961 0.919 – 1.01 0.0883 2123 19952 all phecode
681.5 Cellulitis and abscess of leg, except foot Dermatologic 0.963 0.922 – 1.01 0.0993 2252 20944 all phecode
681.6 Cellulitis and abscess of foot, toe Dermatologic 0.94 0.895 – 0.987 0.0136 1820 16893 all phecode
681.7 Cellulitis and abscess of trunk Dermatologic 0.945 0.897 – 0.996 0.0351 1572 15588 all phecode
686
Other local infections of skin and subcutaneous
Other local infections of skin and subcutaneous tissue
 Dermatologic 0.949 0.908 – 0.991 0.0182 2257 21750 all phecode
686.1 Carbuncle and furuncle Dermatologic 0.998 0.914 – 1.09 0.969 558 5504 all phecode
686.2 Impetigo Dermatologic 0.967 0.873 – 1.07 0.521 414 4117 all phecode
686.3 Pilonidal cyst Dermatologic 0.776 0.657 – 0.916 0.00272 160 1594 all phecode
686.4 Pyogenic granuloma Dermatologic 0.899 0.762 – 1.06 0.21 158 1570 all phecode
686.5 Pyoderma Dermatologic 1.08 0.838 – 1.4 0.546 63 630 all phecode
687 Symptoms affecting skin Dermatologic 1.01 0.955 – 1.06 0.845 1690 16343 all phecode
687.1 Rash and other nonspecific skin eruption Dermatologic 1 0.977 – 1.03 0.812 7007 34623 all phecode
687.3 Changes in skin texture Dermatologic 0.972 0.879 – 1.07 0.581 415 4121 all phecode
687.4 Disturbance of skin sensation Dermatologic 0.979 0.953 – 1.01 0.131 6375 34216 all phecode
689 Disorder of skin and subcutaneous tissue NOS Dermatologic 0.987 0.964 – 1.01 0.273 9311 37335 all phecode
690 Erythematosquamous dermatosis Dermatologic 0.994 0.964 – 1.02 0.672 5184 31581 all phecode
690.1 Seborrheic dermatitis Dermatologic 0.994 0.964 – 1.02 0.676 5174 31553 all phecode
691 Congenital anomalies of skin Dermatologic 0.968 0.883 – 1.06 0.483 541 5337 all phecode
691.3 Congenital pigmentary anomalies of skin Dermatologic 0.759 0.581 – 0.992 0.0438 62 613 all phecode
694 Dyschromia and Vitiligo Dermatologic 0.991 0.944 – 1.04 0.703 1861 17936 all phecode
694.1 Vitiligo Dermatologic 0.93 0.784 – 1.1 0.406 137 1347 all phecode
694.2 Other dyschromia Dermatologic 0.993 0.944 – 1.05 0.801 1674 16183 all phecode
694.3 Vascular disorders of skin Dermatologic 0.994 0.787 – 1.26 0.962 82 819 all phecode
695 Erythematous conditions Dermatologic 0.982 0.95 – 1.02 0.291 4120 30247 all phecode
695.1 Toxic erythema Dermatologic 0.908 0.713 – 1.16 0.435 70 688 all phecode
695.2 Bullous dermatoses Dermatologic 1.04 0.83 – 1.3 0.737 85 805 all phecode
695.3 Rosacea Dermatologic 1.02 0.967 – 1.07 0.551 1816 17663 all phecode
695.4 Lupus (localized and systemic) Dermatologic 0.956 0.883 – 1.03 0.263 672 6686 all phecode
695.41 Cutaneous lupus erythematosus Dermatologic 0.98 0.86 – 1.12 0.766 247 2437 all phecode
695.42 Systemic lupus erythematosus Dermatologic 0.958 0.883 – 1.04 0.299 637 6337 all phecode
695.7 Prurigo and Lichen Dermatologic 1 0.922 – 1.09 0.941 605 5986 all phecode
695.8 Other specified erythematous conditions Dermatologic 0.946 0.88 – 1.02 0.134 812 7980 all phecode
695.81 Erythema nodosum Dermatologic 1.07 0.806 – 1.41 0.646 55 550 all phecode
695.9 Unspecified erythematous condition Dermatologic 1.02 0.938 – 1.1 0.706 679 6756 all phecode
696 Psoriasis and related disorders Dermatologic 0.99 0.937 – 1.05 0.722 1401 13832 all phecode
696.3 Pityriasis Dermatologic 0.922 0.741 – 1.15 0.464 92 904 all phecode
696.4 Psoriasis Dermatologic 0.995 0.939 – 1.05 0.852 1311 12976 all phecode
696.41 Psoriasis vulgaris Dermatologic 1.01 0.949 – 1.07 0.81 1200 11867 all phecode
696.42 Psoriatic arthropathy Dermatologic 0.961 0.849 – 1.09 0.528 282 2810 all phecode
697 Sarcoidosis Dermatologic 0.926 0.826 – 1.04 0.184 333 3330 all phecode
698 Pruritus and related conditions Dermatologic 1.01 0.965 – 1.05 0.716 2254 21889 all phecode
700 Corns and callosities Dermatologic 0.974 0.919 – 1.03 0.37 1373 10894 all phecode
701
Other hypertrophic and atrophic conditions of
Other hypertrophic and atrophic conditions of skin
 Dermatologic 0.994 0.969 – 1.02 0.631 7651 38050 all phecode
701.1 Keratoderma, acquired Dermatologic 0.879 0.805 – 0.96 0.00422 567 5524 all phecode
701.2 Scar conditions and fibrosis of skin Dermatologic 1.04 0.993 – 1.09 0.0971 2184 21550 all phecode
701.3 Circumscribed scleroderma Dermatologic 0.979 0.898 – 1.07 0.634 571 5660 all phecode
701.4 Keloid scar Dermatologic 1.12 1.03 – 1.22 0.01 578 5716 all phecode
701.5 Abnormal granulation tissue Dermatologic 1.02 0.919 – 1.13 0.723 400 3982 all phecode
702
Degenerative skin conditions and other
Degenerative skin conditions and other dermatoses
 Dermatologic 1.01 0.985 – 1.04 0.387 6956 29525 all phecode
702.1 Actinic keratosis Dermatologic 1.01 0.979 – 1.05 0.468 4171 26529 all phecode
702.2 Seborrheic keratosis Dermatologic 1 0.974 – 1.03 0.84 5480 31552 all phecode
702.4 Degenerative skin disorders Dermatologic 1.21 0.959 – 1.52 0.108 86 832 all phecode
703 Diseases of nail, NOS Dermatologic 1.01 0.96 – 1.06 0.676 1650 14562 all phecode
703.1 Ingrowing nail Dermatologic 0.97 0.905 – 1.04 0.383 920 8597 all phecode
704 Diseases of hair and hair follicles Dermatologic 1 0.965 – 1.04 0.925 3118 29542 all phecode
704.1 Alopecia Dermatologic 1.03 0.978 – 1.09 0.235 1408 13871 all phecode
704.11 Alopecia Areata Dermatologic 1.12 0.897 – 1.4 0.314 82 811 all phecode
704.12 Telogen effluvium Dermatologic 1.03 0.793 – 1.33 0.833 63 615 all phecode
704.2 Hirsutism Dermatologic 1 0.888 – 1.14 0.946 299 2946 all phecode
704.8
Other specified diseases of hair and hair
Other specified diseases of hair and hair follicles
 Dermatologic 0.977 0.929 – 1.03 0.36 1752 17189 all phecode
705 Disorders of sweat glands Dermatologic 0.898 0.826 – 0.977 0.0127 603 6012 all phecode
705.1 Dyshidrosis Dermatologic 0.96 0.814 – 1.13 0.632 154 1540 all phecode
705.3 Hidradenitis Dermatologic 0.9 0.788 – 1.03 0.122 245 2440 all phecode
705.8 Hyperhidrosis Dermatologic 0.968 0.909 – 1.03 0.3 1112 10986 all phecode
706 Diseases of sebaceous glands Dermatologic 0.985 0.958 – 1.01 0.273 5995 39748 all phecode
706.1 Acne Dermatologic 0.998 0.958 – 1.04 0.928 2594 22570 all phecode
706.2 Sebaceous cyst Dermatologic 0.981 0.943 – 1.02 0.332 2814 26819 all phecode
706.3 Seborrhea Dermatologic 0.862 0.664 – 1.12 0.266 59 582 all phecode
706.8 Other specified diseases of sebaceous glands Dermatologic 0.941 0.895 – 0.991 0.0206 1684 15289 all phecode
707 Chronic ulcer of skin Dermatologic 0.956 0.92 – 0.994 0.0248 2871 26816 all phecode
707.1 Decubitus ulcer Dermatologic 0.97 0.902 – 1.04 0.407 825 8119 all phecode
707.2 Chronic ulcer of leg or foot Dermatologic 0.924 0.868 – 0.983 0.0123 1108 9992 all phecode
707.3 Chronic ulcer of unspecified site Dermatologic 0.967 0.919 – 1.02 0.203 1641 16172 all phecode
709 Diffuse diseases of connective tissue Dermatologic 0.983 0.931 – 1.04 0.534 1477 14427 all phecode
709.2 Sicca syndrome Dermatologic 0.993 0.906 – 1.09 0.887 505 4986 all phecode
709.3 Systemic sclerosis Dermatologic 1.04 0.909 – 1.2 0.541 224 2209 all phecode
709.5 Dermatomyositis Dermatologic 1.04 0.847 – 1.29 0.69 92 892 all phecode
709.6
Other specified diffuse diseases of connective
Other specified diffuse diseases of connective tissue
 Dermatologic 1.06 0.853 – 1.31 0.608 90 892 all phecode
709.7 Unspecified diffuse connective tissue disease Dermatologic 0.948 0.885 – 1.02 0.127 917 9089 all phecode
710
Osteomyelitis, periostitis, and other
Osteomyelitis, periostitis, and other infections involving bone
 Musculoskeletal 0.983 0.927 – 1.04 0.575 1254 12103 all phecode
710.1 Osteomyelitis Musculoskeletal 0.98 0.923 – 1.04 0.509 1203 11636 all phecode
710.11 Acute osteomyelitis Musculoskeletal 0.92 0.844 – 1 0.0564 590 5708 all phecode
710.12 Chronic osteomyelitis Musculoskeletal 0.989 0.903 – 1.08 0.81 531 5163 all phecode
710.19 Unspecified osteomyelitis Musculoskeletal 0.991 0.932 – 1.05 0.774 1153 11149 all phecode
711 Arthropathy associated with infections Musculoskeletal 0.946 0.853 – 1.05 0.292 410 4099 all phecode
711.1 Pyogenic arthritis Musculoskeletal 0.917 0.812 – 1.04 0.165 290 2900 all phecode
712 Infective connective tissue disorders Musculoskeletal 1.02 0.878 – 1.19 0.763 178 1776 all phecode
713
Arthropathy associated with other disorders
Arthropathy associated with other disorders classified elsewhere
 Musculoskeletal 0.93 0.825 – 1.05 0.231 314 3028 all phecode
713.5
Arthropathy associated with neurological
Arthropathy associated with neurological disorders
 Musculoskeletal 0.893 0.767 – 1.04 0.147 194 1824 all phecode
714
Rheumatoid arthritis and other inflammatory
Rheumatoid arthritis and other inflammatory polyarthropathies
 Musculoskeletal 0.998 0.953 – 1.04 0.921 2086 18159 all phecode
714.1 Rheumatoid arthritis Musculoskeletal 0.992 0.943 – 1.04 0.772 1670 15087 all phecode
714.2 Juvenile rheumatoid arthritis Musculoskeletal 0.951 0.741 – 1.22 0.689 77 767 all phecode
715 Other inflammatory spondylopathies Musculoskeletal 0.974 0.917 – 1.03 0.387 1209 11967 all phecode
715.1 Sacroiliitis NEC Musculoskeletal 0.945 0.83 – 1.07 0.386 262 2611 all phecode
715.2 Ankylosing spondylitis Musculoskeletal 0.931 0.807 – 1.07 0.325 219 2182 all phecode
716 Other arthropathies Musculoskeletal 0.973 0.952 – 0.994 0.0108 13482 31305 all phecode
716.1 Unspecified polyarthropathy or polyarthritis Musculoskeletal 1.02 0.883 – 1.19 0.753 192 1920 all phecode
716.2 Unspecified monoarthritis Musculoskeletal 1.2 0.998 – 1.45 0.0531 131 1293 all phecode
716.9 Arthropathy NOS Musculoskeletal 0.972 0.951 – 0.993 0.00838 13410 31294 all phecode
717 Polymyalgia Rheumatica Musculoskeletal 1.05 0.925 – 1.19 0.446 261 2565 all phecode
720 Spinal stenosis Musculoskeletal 0.986 0.953 – 1.02 0.403 3958 28539 all phecode
720.1 Spinal stenosis of lumbar region Musculoskeletal 0.976 0.938 – 1.01 0.22 2872 23656 all phecode
721 Spondylosis and allied disorders Musculoskeletal 0.994 0.965 – 1.02 0.678 5509 32391 all phecode
721.1 Spondylosis without myelopathy Musculoskeletal 0.996 0.966 – 1.03 0.785 5153 31896 all phecode
721.2 Spondylosis with myelopathy Musculoskeletal 0.972 0.905 – 1.04 0.427 867 8629 all phecode
721.8 Other allied disorders of spine Musculoskeletal 0.972 0.855 – 1.11 0.664 262 2600 all phecode
722 Intervertebral disc disorders Musculoskeletal 0.973 0.947 – 1 0.0541 6284 34317 all phecode
722.1 Displacement of intervertebral disc Musculoskeletal 0.975 0.941 – 1.01 0.153 3591 31411 all phecode
722.3 Schmorl's nodes Musculoskeletal 0.966 0.802 – 1.16 0.715 126 1248 all phecode
722.6 Degeneration of intervertebral disc Musculoskeletal 0.987 0.954 – 1.02 0.446 3957 30744 all phecode
722.7 Intervertebral disc disorder with myelopathy Musculoskeletal 1.02 0.93 – 1.12 0.695 515 5140 all phecode
722.8 Postlaminectomy syndrome Musculoskeletal 0.959 0.865 – 1.06 0.432 397 3968 all phecode
722.9 Other and unspecified disc disorder Musculoskeletal 0.966 0.922 – 1.01 0.157 1932 19288 all phecode
723 Other disorders of cervical region Musculoskeletal 0.983 0.919 – 1.05 0.618 952 9495 all phecode
723.1 Torticollis Musculoskeletal 1 0.878 – 1.15 0.961 254 2522 all phecode
724 Other and unspecified disorders of back Musculoskeletal 0.989 0.957 – 1.02 0.525 4130 31954 all phecode
724.1 Disorders of sacrum Musculoskeletal 0.984 0.942 – 1.03 0.477 2307 21902 all phecode
724.2 Disorders of coccyx Musculoskeletal 1.03 0.932 – 1.14 0.564 426 4215 all phecode
724.8 Other symptoms referable to back Musculoskeletal 1.02 0.953 – 1.09 0.569 931 9295 all phecode
724.9 Other unspecified back disorders Musculoskeletal 0.985 0.933 – 1.04 0.6 1412 14087 all phecode
726 Peripheral enthesopathies and allied syndromes Musculoskeletal 0.987 0.964 – 1.01 0.262 9917 30176 all phecode
726.1 Enthesopathy Musculoskeletal 0.99 0.964 – 1.02 0.427 7507 30106 all phecode
726.2 Synoviopathy Musculoskeletal 0.968 0.907 – 1.03 0.33 1015 9987 all phecode
726.3 Bursitis Musculoskeletal 0.987 0.939 – 1.04 0.597 1829 16722 all phecode
726.4 Calcaneal spur; Exostosis NOS Musculoskeletal 0.981 0.923 – 1.04 0.523 1193 11485 all phecode
727 Other disorders of synovium, tendon, and bursa Musculoskeletal 0.987 0.962 – 1.01 0.327 7425 30105 all phecode
727.1 Synovitis and tenosynovitis Musculoskeletal 0.964 0.928 – 1 0.0627 3092 24998 all phecode
727.2 Bursitis disorders Musculoskeletal 1 0.905 – 1.11 0.972 419 4112 all phecode
727.4 Ganglion and cyst of synovium, tendon, and bursa Musculoskeletal 0.98 0.926 – 1.04 0.472 1400 13621 all phecode
727.5 Rupture of synovium Musculoskeletal 0.983 0.895 – 1.08 0.721 480 4672 all phecode
727.6 Rupture of tendon, nontraumatic Musculoskeletal 0.989 0.948 – 1.03 0.598 2461 21948 all phecode
727.7 Contracture of tendon (sheath) Musculoskeletal 0.959 0.88 – 1.04 0.333 591 5893 all phecode
727.8 Plica syndrome Musculoskeletal 0.981 0.814 – 1.18 0.839 130 1264 all phecode
728 Disorders of muscle, ligament, and fascia Musculoskeletal 0.971 0.941 – 1 0.0718 4546 29473 all phecode
728.1 Muscular calcification and ossification Musculoskeletal 1.05 0.843 – 1.32 0.644 85 843 all phecode
728.2 Laxity of ligament or hypermobility syndrome Musculoskeletal 1.03 0.911 – 1.16 0.672 297 2949 all phecode
728.7 Fasciitis Musculoskeletal 0.988 0.95 – 1.03 0.569 2814 23463 all phecode
728.71
Contracture of palmar fascia [Dupuytren's
Contracture of palmar fascia [Dupuytren's disease]
 Musculoskeletal 0.981 0.887 – 1.09 0.717 419 4138 all phecode
729 Other disorders of soft tissues Musculoskeletal 0.952 0.919 – 0.986 0.0065 3642 27471 all phecode
729.1 Rheumatism, unspecified and fibrositis Musculoskeletal 1.04 0.817 – 1.32 0.761 74 726 all phecode
729.3 Panniculitis Musculoskeletal 0.966 0.798 – 1.17 0.718 119 1174 all phecode
729.7 Nontraumatic compartment syndrome Musculoskeletal 0.879 0.691 – 1.12 0.293 67 664 all phecode
731
Osteitis deformans and osteopathies associated
Osteitis deformans and osteopathies associated with other disorders classified elsewhere
 Musculoskeletal 0.83 0.716 – 0.962 0.0131 210 2091 all phecode
732 Osteochondropathies Musculoskeletal 0.882 0.79 – 0.985 0.0262 361 3604 all phecode
732.1 Juvenile osteochondrosis Musculoskeletal 0.834 0.719 – 0.968 0.017 198 1969 all phecode
732.7 Osteochondritis dissecans Musculoskeletal 0.954 0.767 – 1.19 0.673 90 882 all phecode
733 Other disorders of bone and cartilage Musculoskeletal 1.02 0.992 – 1.06 0.145 4543 26941 all phecode
733.2 Cyst of bone Musculoskeletal 1.01 0.867 – 1.17 0.935 190 1900 all phecode
733.4 Aseptic necrosis of bone Musculoskeletal 1.09 0.996 – 1.2 0.0607 518 5160 all phecode
733.6 Costochondritis Musculoskeletal 0.963 0.861 – 1.08 0.502 357 3562 all phecode
733.8 Malunion and nonunion of fracture Musculoskeletal 1.04 0.968 – 1.12 0.278 822 8205 all phecode
733.9 Chondromalacia Musculoskeletal 0.98 0.798 – 1.2 0.844 96 960 all phecode
735 Acquired foot deformities Musculoskeletal 1.02 0.981 – 1.05 0.357 3417 29622 all phecode
735.1 Flat foot Musculoskeletal 0.946 0.871 – 1.03 0.188 620 6092 all phecode
735.2 Acquired toe deformities Musculoskeletal 1.01 0.951 – 1.07 0.786 1323 11983 all phecode
735.21 Hammer toe (acquired) Musculoskeletal 1.03 0.958 – 1.11 0.426 825 7494 all phecode
735.23 Hallux rigidus Musculoskeletal 0.984 0.888 – 1.09 0.754 405 4005 all phecode
735.3 Hallux valgus (Bunion) Musculoskeletal 1.06 1 – 1.12 0.047 1470 14295 all phecode
736 Other acquired deformities of limbs Musculoskeletal 1.01 0.967 – 1.05 0.762 2763 26555 all phecode
736.1 Acquired deformities of forearm Musculoskeletal 0.909 0.747 – 1.11 0.342 104 1033 all phecode
736.2 Acquired deformities of finger Musculoskeletal 0.94 0.819 – 1.08 0.381 215 2142 all phecode
736.3 Acquired deformities of hip Musculoskeletal 0.783 0.603 – 1.02 0.067 60 590 all phecode
736.4 Genu valgum or varum (acquired) Musculoskeletal 1.08 0.966 – 1.22 0.17 325 3247 all phecode
736.5 Acquired deformities of knee Musculoskeletal 1.06 0.924 – 1.21 0.421 246 2460 all phecode
736.6 Unequal leg length (acquired) Musculoskeletal 1.08 0.968 – 1.21 0.16 339 3365 all phecode
737 Curvature of spine Musculoskeletal 1.02 0.966 – 1.07 0.501 1566 15543 all phecode
737.1 Kyphosis (acquired) Musculoskeletal 0.999 0.909 – 1.1 0.978 479 4748 all phecode
737.2 Lordosis (acquired) Musculoskeletal 0.97 0.756 – 1.24 0.809 70 700 all phecode
737.3 Kyphoscoliosis and scoliosis Musculoskeletal 1.02 0.965 – 1.09 0.431 1203 11982 all phecode
738 Other acquired musculoskeletal deformity Musculoskeletal 1.01 0.967 – 1.05 0.676 2443 24187 all phecode
738.4 Acquired spondylolisthesis Musculoskeletal 0.989 0.927 – 1.06 0.745 1057 10542 all phecode
739 Contracture of joint Musculoskeletal 1.04 0.955 – 1.13 0.378 621 6207 all phecode
740 Osteoarthrosis Musculoskeletal 0.977 0.958 – 0.997 0.0276 16169 30268 all phecode
740.1 Osteoarthritis; localized Musculoskeletal 0.983 0.956 – 1.01 0.223 7005 27422 all phecode
740.11 Osteoarthrosis, localized, primary Musculoskeletal 0.986 0.958 – 1.02 0.355 6176 26155 all phecode
740.12 Osteoarthrosis, localized, secondary Musculoskeletal 0.993 0.919 – 1.07 0.868 713 7116 all phecode
740.2 Osteoarthrosis, generalized Musculoskeletal 0.983 0.932 – 1.04 0.525 1609 12092 all phecode
740.3
Osteoarthrosis involving more than one site
Osteoarthrosis involving more than one site, but not specified as generalized
 Musculoskeletal 0.964 0.865 – 1.07 0.509 373 3586 all phecode
740.9 Osteoarthrosis NOS Musculoskeletal 0.976 0.956 – 0.997 0.0244 15497 30141 all phecode
741 Symptoms and disorders of the joints Musculoskeletal 0.997 0.973 – 1.02 0.782 8555 35884 all phecode
741.1 Ankylosis of joint Musculoskeletal 0.963 0.844 – 1.1 0.572 245 2445 all phecode
741.2 Stiffness of joint Musculoskeletal 1.02 0.958 – 1.08 0.597 1268 12594 all phecode
741.3 Difficulty in walking Musculoskeletal 0.972 0.933 – 1.01 0.178 2558 23116 all phecode
741.4 Joint effusions Musculoskeletal 0.974 0.934 – 1.02 0.216 2493 24199 all phecode
741.5 Hemarthrosis Musculoskeletal 0.986 0.804 – 1.21 0.891 94 937 all phecode
741.6 Villonodular synovitis Musculoskeletal 0.764 0.595 – 0.982 0.0355 68 666 all phecode
742 Derangement of joint, non-traumatic Musculoskeletal 1 0.968 – 1.03 0.985 4404 33771 all phecode
742.1 Loose body in joint Musculoskeletal 0.953 0.812 – 1.12 0.562 156 1554 all phecode
742.2
Pathological, developmental or recurrent
Pathological, developmental or recurrent dislocation
 Musculoskeletal 1.02 0.906 – 1.16 0.697 280 2792 all phecode
742.8 Articular cartilage disorder Musculoskeletal 1.05 0.92 – 1.2 0.471 245 2450 all phecode
742.9 Other derangement of joint Musculoskeletal 0.995 0.963 – 1.03 0.786 4107 32972 all phecode
743
Osteoporosis, osteopenia and pathological
Osteoporosis, osteopenia and pathological fracture
 Musculoskeletal 1.03 1.01 – 1.06 0.00648 9223 36921 all phecode
743.1 Osteoporosis Musculoskeletal 1.07 1.03 – 1.11 0.000625 3712 19477 all phecode
743.11 Osteoporosis NOS Musculoskeletal 1.07 1.03 – 1.11 0.000571 3657 19276 all phecode
743.12 Senile osteoporosis Musculoskeletal 1.13 1.04 – 1.22 0.00313 703 5804 all phecode
743.13 Other specified osteoporosis Musculoskeletal 1.02 0.912 – 1.15 0.685 321 3141 all phecode
743.2 Pathologic fracture Musculoskeletal 0.988 0.929 – 1.05 0.713 1112 10563 all phecode
743.21 Pathologic fracture of vertebrae Musculoskeletal 0.919 0.837 – 1.01 0.0794 475 4629 all phecode
743.22 Pathologic fracture of femur Musculoskeletal 0.885 0.741 – 1.06 0.179 143 1391 all phecode
743.4 Stress fracture Musculoskeletal 0.998 0.901 – 1.11 0.971 407 4046 all phecode
743.9
Osteopenia or other disorder of bone and
Osteopenia or other disorder of bone and cartilage
 Musculoskeletal 1.03 1 – 1.06 0.0438 6970 35237 all phecode
745 Pain in joint Musculoskeletal 0.996 0.978 – 1.01 0.68 19848 26918 all phecode
747 Cardiac and circulatory congenital anomalies Congenital Anomalies 0.98 0.938 – 1.02 0.364 2236 22256 all phecode
747.1 Cardiac congenital anomalies Congenital Anomalies 0.965 0.919 – 1.01 0.164 1767 17598 all phecode
747.11 Cardiac shunt/ heart septal defect Congenital Anomalies 1.03 0.952 – 1.12 0.433 650 6497 all phecode
747.12 Valvular heart disease/ heart chambers Congenital Anomalies 0.936 0.867 – 1.01 0.0904 751 7480 all phecode
747.13 Congenital anomalies of great vessels Congenital Anomalies 0.879 0.794 – 0.974 0.0136 410 4090 all phecode
747.2
Congenital anomalies of peripheral vascular
Congenital anomalies of peripheral vascular system
 Congenital Anomalies 1.03 0.939 – 1.13 0.529 501 5010 all phecode
748 Anomalies of respiratory system, congenital Congenital Anomalies 0.86 0.706 – 1.05 0.133 111 1110 all phecode
749 Congenital anomalies of face and neck Congenital Anomalies 1.02 0.932 – 1.11 0.721 555 5549 all phecode
749.1 Cleft palate Congenital Anomalies 1.07 0.877 – 1.32 0.486 97 970 all phecode
749.2 Congenital anomalies of skull and face bones Congenital Anomalies 0.833 0.684 – 1.02 0.07 105 1041 all phecode
750 Digestive congenital anomalies Congenital Anomalies 1.03 0.965 – 1.11 0.34 893 8919 all phecode
750.1 Upper gastrointestinal congenital anomalies Congenital Anomalies 1.02 0.918 – 1.14 0.669 366 3655 all phecode
750.11 Esophageal atresia/tracheoesophageal fistula Congenital Anomalies 0.993 0.821 – 1.2 0.944 119 1185 all phecode
750.13 Congenital anomalies of mouth/tongue Congenital Anomalies 1.05 0.856 – 1.29 0.63 99 982 all phecode
750.14 Congenital anomalies of esophagus Congenital Anomalies 0.963 0.807 – 1.15 0.674 134 1332 all phecode
750.15 Congenital anomalies of stomach Congenital Anomalies 0.951 0.721 – 1.26 0.724 60 593 all phecode
750.2 Lower gastrointestinal congenital anomalies Congenital Anomalies 1.05 0.955 – 1.15 0.327 531 5300 all phecode
750.21 Congenital anomalies of intestine Congenital Anomalies 1.02 0.902 – 1.14 0.795 313 3129 all phecode
750.22
Congenital anomaly of gallbladder, bile ducts
Congenital anomaly of gallbladder, bile ducts, liver, pancreas
 Congenital Anomalies 1.04 0.898 – 1.2 0.623 222 2214 all phecode
751 Genitourinary congenital anomalies Congenital Anomalies 0.956 0.912 – 1 0.0564 2008 19975 all phecode
751.1 Congenital anomalies of genital organs Congenital Anomalies 0.984 0.902 – 1.07 0.725 574 5740 all phecode
751.11 Congenital anomalies of female genital organs Congenital Anomalies 0.987 0.887 – 1.1 0.817 384 3840 all phecode
751.12 Congenital anomalies of male genital organs Congenital Anomalies 1.01 0.855 – 1.19 0.927 153 1527 all phecode
751.2 Congenital anomalies of urinary system Congenital Anomalies 0.957 0.904 – 1.01 0.122 1379 13704 all phecode
751.21 Cystic kidney disease Congenital Anomalies 0.957 0.896 – 1.02 0.2 976 9685 all phecode
751.22 Other specified congenital anomalies of kidney Congenital Anomalies 0.888 0.787 – 1 0.0548 294 2927 all phecode
751.3 Obstructive genitourinary defect Congenital Anomalies 0.889 0.761 – 1.04 0.137 182 1809 all phecode
752 Nervous system congenital anomalies Congenital Anomalies 1 0.94 – 1.07 0.979 1133 11313 all phecode
752.1 Neural tube defects Congenital Anomalies 0.992 0.926 – 1.06 0.814 923 9209 all phecode
752.11 Spina bifida Congenital Anomalies 1.12 0.964 – 1.31 0.137 176 1760 all phecode
752.2
Other specified congenital anomalies of nervous
Other specified congenital anomalies of nervous system
 Congenital Anomalies 1.06 0.921 – 1.21 0.426 232 2320 all phecode
753 Congenital anomalies of the eye Congenital Anomalies 0.886 0.767 – 1.02 0.103 207 2051 all phecode
753.1 Congenital cataract and lens anomalies Congenital Anomalies 0.888 0.677 – 1.16 0.389 58 580 all phecode
753.2 Congenital anomalies of posterior segment of eye Congenital Anomalies 0.896 0.674 – 1.19 0.45 56 546 all phecode
754 Congenital musculoskeletal deformities of spine Congenital Anomalies 1.01 0.948 – 1.07 0.845 1216 12116 all phecode
754.1 Lumbosacral spondylolysis, congenital Congenital Anomalies 1.14 0.954 – 1.37 0.148 135 1333 all phecode
754.2 Spondylolisthesis, congenital Congenital Anomalies 1 0.919 – 1.1 0.945 558 5570 all phecode
755 Congenital anomalies of limbs Congenital Anomalies 1 0.928 – 1.08 0.972 747 7458 all phecode
755.1 Congenital deformities of feet Congenital Anomalies 0.997 0.897 – 1.11 0.953 368 3663 all phecode
755.4
Congenital anomalies of upper limb, including
Congenital anomalies of upper limb, including shoulder girdle
 Congenital Anomalies 1.24 0.984 – 1.57 0.0677 74 740 all phecode
755.6
Other congenital anomalies of lower limb
Other congenital anomalies of lower limb, including pelvic girdle
 Congenital Anomalies 0.955 0.849 – 1.07 0.438 321 3205 all phecode
755.61 Congenital hip dysplasia and deformity Congenital Anomalies 0.969 0.83 – 1.13 0.69 185 1847 all phecode
756 Other congenital musculoskeletal anomalies Congenital Anomalies 0.985 0.93 – 1.04 0.591 1358 13579 all phecode
756.1 Congenital anomalies of abdominal wall; diaphram Congenital Anomalies 0.947 0.738 – 1.22 0.67 68 680 all phecode
756.2
Pectus and other congenital anomalies of
Pectus and other congenital anomalies of ribs/sternum
 Congenital Anomalies 0.9 0.695 – 1.17 0.428 71 694 all phecode
756.3
Congenital anomalies of muscle, tendon, fascia
Congenital anomalies of muscle, tendon, fascia, and connective tissue
 Congenital Anomalies 1.03 0.914 – 1.15 0.665 335 3346 all phecode
756.5 Congenital osteodystrophies Congenital Anomalies 0.989 0.925 – 1.06 0.735 1003 10014 all phecode
757 Congenital anomalies of the integument Congenital Anomalies 0.969 0.872 – 1.08 0.552 401 4001 all phecode
758 Chromosomal anomalies and genetic disorders Congenital Anomalies 1.12 0.958 – 1.3 0.157 185 1845 all phecode
758.1 Chromosomal anomalies Congenital Anomalies 1.13 0.949 – 1.35 0.168 135 1349 all phecode
759 Other and unspecified congenital anomalies Congenital Anomalies 0.994 0.908 – 1.09 0.888 557 5566 all phecode
759.1 Anomalies of endocrine glands, congenital Congenital Anomalies 0.902 0.703 – 1.16 0.42 71 710 all phecode
760 Back pain Symptoms 0.974 0.955 – 0.993 0.00868 16037 30719 all phecode
761 Cervicalgia Symptoms 0.986 0.96 – 1.01 0.285 6528 39755 all phecode
763
Thoracic or lumbosacral neuritis or
Thoracic or lumbosacral neuritis or radiculitis, unspecified
 Symptoms 0.976 0.942 – 1.01 0.162 3657 32599 all phecode
764 Sciatica Symptoms 0.977 0.943 – 1.01 0.195 3542 32015 all phecode
765 Cervical radiculitis Symptoms 0.953 0.907 – 1 0.0546 1799 17851 all phecode
766 Neuralgia, neuritis, and radiculitis NOS Symptoms 0.974 0.946 – 1 0.0823 5124 37132 all phecode
767 Cervicocranial/Cervicobrachial syndrome Symptoms 0.909 0.752 – 1.1 0.325 117 1168 all phecode
769 Nonallopathic lesions NEC Symptoms 0.998 0.938 – 1.06 0.95 1131 11220 all phecode
770 Myalgia and myositis unspecified Symptoms 0.957 0.93 – 0.985 0.003 5533 34303 all phecode
771 Musculoskeletal symptoms referable to limbs Symptoms 0.984 0.954 – 1.01 0.305 4799 35575 all phecode
771.1 Swelling of limb Symptoms 0.98 0.952 – 1.01 0.161 5743 35539 all phecode
771.2 Cramp of limb Symptoms 0.936 0.878 – 0.998 0.0423 1079 10568 all phecode
772 Symptoms of the muscles Symptoms 1 0.955 – 1.05 0.985 2042 20221 all phecode
772.1 Muscular wasting and disuse atrophy Symptoms 1.09 0.986 – 1.21 0.0936 422 4199 all phecode
772.2 Spasm of muscle Symptoms 0.962 0.921 – 1.01 0.0845 2299 22726 all phecode
772.3 Muscle weakness Symptoms 0.974 0.937 – 1.01 0.183 2949 28064 all phecode
772.4 Rhabdomyolysis Symptoms 1.03 0.874 – 1.21 0.734 159 1572 all phecode
772.6 Facial weakness Symptoms 0.948 0.863 – 1.04 0.269 478 4742 all phecode
780 Hypothermia/Chills Symptoms 0.962 0.871 – 1.06 0.446 453 4514 all phecode
781
Symptoms involving nervous and musculoskeletal
Symptoms involving nervous and musculoskeletal systems
 Symptoms 1 0.964 – 1.04 0.881 2822 26225 all phecode
781.1 Loss of height Symptoms 1.29 1.08 – 1.55 0.00447 130 1269 all phecode
781.2 Abnormal posture Symptoms 0.969 0.748 – 1.26 0.814 57 567 all phecode
782.3 Edema Symptoms 0.962 0.936 – 0.99 0.00761 5874 36788 all phecode
782.6 Pallor and flushing Symptoms 1.03 0.959 – 1.1 0.446 927 9252 all phecode
783 Fever of unknown origin Symptoms 0.977 0.95 – 1 0.106 5733 40720 all phecode
783.1 Postprocedural fever Symptoms 0.932 0.828 – 1.05 0.241 300 2992 all phecode
785 Abdominal pain Symptoms 0.979 0.96 – 0.998 0.0292 16458 30297 all phecode
788 Syncope and collapse Symptoms 0.993 0.96 – 1.03 0.676 3851 35832 all phecode
789 Nausea and vomiting Symptoms 0.967 0.945 – 0.988 0.00266 10568 36098 all phecode
789.1 Persistent vomiting Symptoms 0.923 0.859 – 0.993 0.0315 798 7924 all phecode
790 Nonspecific findings on examination of blood Symptoms 0.939 0.9 – 0.981 0.00442 2363 22690 all phecode
790.1 Elevated sedimentation rate Symptoms 0.898 0.785 – 1.03 0.118 236 2322 all phecode
790.6 Other abnormal blood chemistry Symptoms 0.955 0.931 – 0.98 0.000421 7539 37788 all phecode
790.8 Elevated C-reactive protein (CRP) Symptoms 0.881 0.782 – 0.992 0.0368 309 3075 all phecode
790.9 Abnormal arterial blood gases Symptoms 0.97 0.82 – 1.15 0.723 155 1521 all phecode
791 Gangrene Symptoms 0.977 0.868 – 1.1 0.702 313 3115 all phecode
792
Abnormal Papanicolaou smear of cervix and
Abnormal Papanicolaou smear of cervix and cervical HPV
 Genitourinary 1.03 0.99 – 1.08 0.134 2820 14872 all phecode
792.1
Papanicolaou smear of cervix or vagina with
Papanicolaou smear of cervix or vagina with atypical squamous cells
 Genitourinary 1.06 0.992 – 1.13 0.0867 1100 9861 all phecode
794
Abnormal results of other function studies
Abnormal results of other function studies (bladder, pancreas, placenta, spleen, etc)
 Symptoms 1.1 1 – 1.2 0.0408 515 5133 all phecode
795
Other and nonspecific abnormal cytological
Other and nonspecific abnormal cytological, histological and immunological findings
 Symptoms 1.03 0.986 – 1.08 0.178 2182 20242 all phecode
795.8 Abnormal tumor markers Symptoms 1 0.953 – 1.05 0.923 1745 15551 all phecode
795.81 Elevated carcinoembryonic antigen [CEA] Symptoms 0.991 0.769 – 1.28 0.942 61 605 all phecode
795.82 Elevated cancer antigen 125 [CA 125] Symptoms 1.01 0.871 – 1.16 0.931 201 2000 all phecode
796 Elevated prostate specific antigen [PSA] Genitourinary 1.04 0.993 – 1.1 0.0899 2125 9930 all phecode
797 Shock Symptoms 0.859 0.79 – 0.935 0.000414 605 6050 all phecode
797.1 Cardiogenic shock Symptoms 0.845 0.739 – 0.967 0.0146 242 2420 all phecode
798 Malaise and fatigue Symptoms 0.987 0.966 – 1.01 0.24 11539 35196 all phecode
798.1 Chronic fatigue syndrome Symptoms 1 0.953 – 1.05 0.973 1823 17795 all phecode
800 Fracture of lower limb Injuries & Poisonings 1.01 0.969 – 1.06 0.613 2344 22951 all phecode
800.1 Fracture of neck of femur Injuries & Poisonings 1.01 0.918 – 1.11 0.868 512 4961 all phecode
800.2 Fracture of unspecified part of femur Injuries & Poisonings 0.969 0.893 – 1.05 0.44 670 6582 all phecode
800.3 Fracture of tibia and fibula Injuries & Poisonings 1.01 0.946 – 1.09 0.684 898 8966 all phecode
800.4 Fracture of patella Injuries & Poisonings 1.04 0.933 – 1.17 0.455 346 3456 all phecode
801 Fracture of ankle and foot Injuries & Poisonings 1.05 1.01 – 1.1 0.0234 2358 22645 all phecode
801.1 Fracture of foot Injuries & Poisonings 1.03 0.969 – 1.1 0.343 1120 11178 all phecode
802 Fracture of pelvis Injuries & Poisonings 1.05 0.939 – 1.16 0.419 380 3765 all phecode
803 Fracture of upper limb Injuries & Poisonings 1.01 0.962 – 1.05 0.772 2051 20360 all phecode
803.1 Fracture of humerus Injuries & Poisonings 0.976 0.904 – 1.05 0.534 734 7322 all phecode
803.2 Fracture of radius and ulna Injuries & Poisonings 1.02 0.959 – 1.09 0.526 1112 11075 all phecode
803.21 Colles' fracture Injuries & Poisonings 1.03 0.916 – 1.17 0.589 291 2904 all phecode
803.3 Fracture of clavicle or scapula Injuries & Poisonings 1.03 0.938 – 1.12 0.564 514 5140 all phecode
804 Fracture of hand or wrist Injuries & Poisonings 1.03 0.981 – 1.09 0.215 1628 16042 all phecode
805
Fracture of vertebral column without mention of
Fracture of vertebral column without mention of spinal cord injury
 Injuries & Poisonings 1.01 0.953 – 1.07 0.762 1336 13242 all phecode
807 Fracture of ribs Injuries & Poisonings 1.02 0.939 – 1.1 0.702 683 6815 all phecode
809 Fracture of unspecified bones Injuries & Poisonings 0.994 0.957 – 1.03 0.777 2941 28633 all phecode
816 Cerebral laceration and contusion Injuries & Poisonings 1 0.757 – 1.32 0.993 54 531 all phecode
817 Concussion Injuries & Poisonings 0.951 0.891 – 1.02 0.133 1018 10149 all phecode
818 Intracranial hemorrhage (injury) Injuries & Poisonings 1.04 0.921 – 1.17 0.556 311 3104 all phecode
818.1 Subdural hemorrhage (injury) Injuries & Poisonings 0.916 0.738 – 1.14 0.425 90 895 all phecode
818.2 Subarachnoid hemorrhage (injury) Injuries & Poisonings 0.915 0.741 – 1.13 0.406 97 970 all phecode
819
Skull and face fracture and other intercranial
Skull and face fracture and other intercranial injury
 Injuries & Poisonings 0.973 0.932 – 1.02 0.225 2287 22671 all phecode
830 Dislocation Injuries & Poisonings 1.01 0.976 – 1.04 0.6 3862 34720 all phecode
835 Internal derangement of knee Injuries & Poisonings 0.978 0.936 – 1.02 0.329 2231 21628 all phecode
836 Traumatic arthropathy Injuries & Poisonings 0.912 0.831 – 1 0.0512 496 4954 all phecode
840 Sprains and strains Injuries & Poisonings 1.01 0.981 – 1.03 0.636 7838 37998 all phecode
840.1 Muscle/tendon sprain Injuries & Poisonings 1 0.919 – 1.1 0.924 537 5356 all phecode
840.2 Rotator cuff (capsule) sprain Injuries & Poisonings 0.973 0.924 – 1.02 0.294 1640 16263 all phecode
840.3 Joint/ligament sprain Injuries & Poisonings 1.02 0.985 – 1.07 0.236 2875 24879 all phecode
841 Sprains and strains of back and neck Injuries & Poisonings 0.973 0.923 – 1.03 0.302 1583 15592 all phecode
842 Other sprains and strains Injuries & Poisonings 0.989 0.936 – 1.05 0.695 1407 13924 all phecode
850 Hemorrhage or hematoma complicating a procedure Injuries & Poisonings 0.997 0.952 – 1.04 0.895 2072 20649 all phecode
851
Complications of transplants and reattached
Complications of transplants and reattached limbs
 Injuries & Poisonings 0.973 0.936 – 1.01 0.155 2982 27545 all phecode
853 Complication of colostomy or enterostomy Injuries & Poisonings 0.978 0.887 – 1.08 0.656 460 4600 all phecode
854
Complications of cardiac/vascular device
Complications of cardiac/vascular device, implant, and graft
 Injuries & Poisonings 0.898 0.857 – 0.941 6.24e-06 1985 19675 all phecode
855
Complication of nervous system device, implant
Complication of nervous system device, implant, and graft
 Injuries & Poisonings 0.875 0.772 – 0.993 0.0379 264 2640 all phecode
856
Vascular complications of surgery and medical
Vascular complications of surgery and medical procedures
 Injuries & Poisonings 0.97 0.858 – 1.1 0.623 293 2929 all phecode
857
Mechanical complication of unspecified
Mechanical complication of unspecified genitourinary device, implant, and graft
 Injuries & Poisonings 0.947 0.894 – 1 0.0654 1310 13087 all phecode
858 Complication of internal orthopedic device Injuries & Poisonings 1.03 0.99 – 1.08 0.128 2213 21944 all phecode
859
Complication due to other implant and internal
Complication due to other implant and internal device
 Injuries & Poisonings 0.962 0.919 – 1.01 0.0906 2110 21070 all phecode
860 Bone marrow or stem cell transplant Neoplasms 0.842 0.715 – 0.991 0.0383 166 1660 all phecode
870 Open wounds of head; neck; and trunk Injuries & Poisonings 0.981 0.949 – 1.01 0.251 4117 36734 all phecode
870.1 Open wound or laceration of eye or eyelid Injuries & Poisonings 0.997 0.862 – 1.15 0.964 204 2026 all phecode
870.2 Open wound of ear Injuries & Poisonings 0.972 0.819 – 1.15 0.746 144 1437 all phecode
870.3 Other open wound of head and face Injuries & Poisonings 0.974 0.92 – 1.03 0.374 1346 13301 all phecode
870.4 Open wound of nose and sinus Injuries & Poisonings 0.876 0.761 – 1.01 0.0668 207 2057 all phecode
870.5 Open wound of lip and mouth Injuries & Poisonings 0.987 0.87 – 1.12 0.839 275 2724 all phecode
870.6 Open wound of neck Injuries & Poisonings 1.1 0.957 – 1.27 0.179 214 2128 all phecode
870.8 Open wound of genital organs Injuries & Poisonings 0.893 0.75 – 1.06 0.202 144 1440 all phecode
871 Open wounds of extremities Injuries & Poisonings 0.987 0.953 – 1.02 0.474 3530 32903 all phecode
871.1 Open wound of hand except finger(s) Injuries & Poisonings 0.991 0.907 – 1.08 0.849 572 5701 all phecode
871.2 Open wound of finger(s) Injuries & Poisonings 0.98 0.917 – 1.05 0.557 984 9772 all phecode
871.3 Open wound of foot except toe(s) alone Injuries & Poisonings 0.917 0.835 – 1.01 0.0669 490 4843 all phecode
871.4 Open wound of toe(s) Injuries & Poisonings 1.01 0.893 – 1.13 0.924 295 2921 all phecode
872 Traumatic amputation Injuries & Poisonings 0.914 0.835 – 0.999 0.0475 551 5477 all phecode
874 Complication of amputation stump Injuries & Poisonings 0.967 0.827 – 1.13 0.669 170 1697 all phecode
875 Non-healing surgical wound Injuries & Poisonings 0.99 0.907 – 1.08 0.815 572 5720 all phecode
876
Posttraumatic wound infection not elsewhere
Posttraumatic wound infection not elsewhere classified
 Injuries & Poisonings 0.989 0.918 – 1.06 0.76 802 8003 all phecode
907 Injuries to the nervous system Injuries & Poisonings 0.997 0.934 – 1.06 0.925 1010 10096 all phecode
910 Superficial injury, infected Injuries & Poisonings 0.943 0.777 – 1.14 0.552 119 1161 all phecode
911 Blister Injuries & Poisonings 1.05 0.929 – 1.18 0.449 302 2996 all phecode
912 Insect bite Injuries & Poisonings 0.947 0.862 – 1.04 0.257 492 4886 all phecode
913 Toxic effect of venom Injuries & Poisonings 1.03 0.922 – 1.15 0.586 337 3326 all phecode
916 Contusion Injuries & Poisonings 1.01 0.974 – 1.04 0.72 4296 38033 all phecode
930 Allergic reaction to food Injuries & Poisonings 0.986 0.913 – 1.06 0.714 763 7596 all phecode
931
Contact dermatitis and other eczema due to
Contact dermatitis and other eczema due to plants [except food]
 Dermatologic 1.02 0.941 – 1.1 0.688 714 7072 all phecode
938 Dermatitis due to solar radiation Dermatologic 1 0.97 – 1.03 0.978 5567 29098 all phecode
938.1 Acute dermatitis due to solar radiation Dermatologic 1.1 0.955 – 1.27 0.184 217 2164 all phecode
938.2 Chronic dermatitis due to solar radiation Dermatologic 0.996 0.967 – 1.03 0.805 5307 28656 all phecode
939
Atopic/contact dermatitis due to other or
Atopic/contact dermatitis due to other or unspecified
 Dermatologic 1 0.976 – 1.03 0.819 6704 32389 all phecode
939.1 Contact and allergic dermatitis of eyelid Dermatologic 0.997 0.798 – 1.25 0.979 91 870 all phecode
941 Adverse reaction to serum or vaccine Injuries & Poisonings 0.871 0.749 – 1.01 0.0719 188 1880 all phecode
942 Infusion and transfusion reaction Injuries & Poisonings 1.02 0.895 – 1.15 0.811 269 2688 all phecode
946 Anaphylactic shock NOS Injuries & Poisonings 1.03 0.938 – 1.13 0.54 500 4940 all phecode
947 Urticaria Dermatologic 0.935 0.879 – 0.994 0.0304 1177 11454 all phecode
949 Allergies, other Injuries & Poisonings 1 0.974 – 1.03 0.984 7251 32350 all phecode
952
Spinal cord injury without evidence of spinal
Spinal cord injury without evidence of spinal bone injury
 Injuries & Poisonings 0.999 0.91 – 1.1 0.983 494 4940 all phecode
957 Injury to other and unspecified nerves Injuries & Poisonings 1.2 1.01 – 1.43 0.0431 136 1352 all phecode
958
Certain early complications of trauma or
Certain early complications of trauma or procedure
 Injuries & Poisonings 0.987 0.929 – 1.05 0.66 1217 12158 all phecode
958.1 Postoperative shock Injuries & Poisonings 0.962 0.819 – 1.13 0.64 169 1688 all phecode
958.2 Traumatic and surgical subcutaneous emphysema Injuries & Poisonings 1.01 0.834 – 1.24 0.882 114 1140 all phecode
960 Poisoning by antibiotics Injuries & Poisonings 0.988 0.947 – 1.03 0.559 2479 22087 all phecode
960.1
Adverse effects of antibacterials (not
Adverse effects of antibacterials (not penicillins)
 Injuries & Poisonings 0.982 0.88 – 1.1 0.753 342 3403 all phecode
960.2 Allergy/adverse effect of penicillin Injuries & Poisonings 0.993 0.943 – 1.05 0.793 1636 16005 all phecode
961 Poisoning by other anti-infectives Injuries & Poisonings 0.984 0.9 – 1.08 0.732 528 5234 all phecode
961.1 Poisoning/allergy of sulfonamides Injuries & Poisonings 0.989 0.929 – 1.05 0.742 1065 10347 all phecode
962 Poisoning by hormones and synthetic substitutes Injuries & Poisonings 0.96 0.892 – 1.03 0.269 803 7976 all phecode
962.1
Adrenal cortical steroids causing adverse
Adrenal cortical steroids causing adverse effects in therapeutic use
 Injuries & Poisonings 1.03 0.922 – 1.14 0.633 379 3782 all phecode
962.2
Insulins and antidiabetic agents causing
Insulins and antidiabetic agents causing adverse effects in therapeutic use
 Injuries & Poisonings 0.774 0.596 – 1 0.0541 62 612 all phecode
962.3
Hormones and synthetic substitutes causing
Hormones and synthetic substitutes causing adverse effects in therapeutic use
 Injuries & Poisonings 0.928 0.844 – 1.02 0.124 478 4773 all phecode
963 Poisoning by primarily systemic agents Injuries & Poisonings 1.02 0.977 – 1.06 0.398 2533 24531 all phecode
963.1
Antineoplastic and immunosuppressive drugs
Antineoplastic and immunosuppressive drugs causing adverse effects
 Injuries & Poisonings 1.02 0.978 – 1.06 0.362 2469 24057 all phecode
964
Poisoning by agents primarily affecting blood
Poisoning by agents primarily affecting blood constituents
 Injuries & Poisonings 0.954 0.884 – 1.03 0.228 743 7337 all phecode
964.1 Anticoagulants causing adverse effects Injuries & Poisonings 0.949 0.877 – 1.03 0.184 712 7027 all phecode
965
Poisoning by analgesics, antipyretics, and
Poisoning by analgesics, antipyretics, and antirheumatics
 Injuries & Poisonings 1.03 0.962 – 1.11 0.368 864 8601 all phecode
965.1
Opiates and related narcotics causing adverse
Opiates and related narcotics causing adverse effects in therapeutic use
 Injuries & Poisonings 0.946 0.896 – 0.999 0.0459 1469 14402 all phecode
965.3
Salicylates causing adverse effects in
Salicylates causing adverse effects in therapeutic use
 Injuries & Poisonings 1.22 0.998 – 1.48 0.0523 119 1182 all phecode
966
Poisoning by anticonvulsants and
Poisoning by anticonvulsants and anti-Parkinsonism drugs
 Injuries & Poisonings 0.873 0.713 – 1.07 0.186 103 1006 all phecode
967
Adverse effects of sedatives or other central
Adverse effects of sedatives or other central nervous system depressants and anesthetics
 Injuries & Poisonings 0.948 0.893 – 1.01 0.0744 1254 12464 all phecode
969 Poisoning by psychotropic agents Injuries & Poisonings 0.945 0.836 – 1.07 0.369 281 2797 all phecode
971
Poisoning by drugs primarily affecting the
Poisoning by drugs primarily affecting the autonomic nervous system
 Injuries & Poisonings 0.949 0.737 – 1.22 0.685 67 643 all phecode
972
Poisoning by agents primarily affecting the
Poisoning by agents primarily affecting the cardiovascular system
 Injuries & Poisonings 0.978 0.865 – 1.11 0.729 288 2858 all phecode
972.1
Cardiac rhythm regulators causing adverse
Cardiac rhythm regulators causing adverse effects in therapeutic use
 Injuries & Poisonings 0.96 0.768 – 1.2 0.719 80 776 all phecode
972.6 Antihypertensive agents causing adverse effects Injuries & Poisonings 1.11 0.899 – 1.36 0.34 104 1034 all phecode
974
Poisoning by water, mineral, and uric acid
Poisoning by water, mineral, and uric acid metabolism drugs
 Injuries & Poisonings 0.863 0.71 – 1.05 0.136 113 1130 all phecode
975
Poisoning by agents primarily acting on the
Poisoning by agents primarily acting on the smooth and skeletal muscles and respiratory system
 Injuries & Poisonings 1.04 0.823 – 1.3 0.767 81 810 all phecode
976
Poisoning by agents primarily affecting skin &
Poisoning by agents primarily affecting skin & mucous membrane, ophthalmological, otorhinolaryngological, & dental drugs
 Injuries & Poisonings 0.973 0.772 – 1.23 0.815 71 703 all phecode
977 Personal history of allergy to medicinal agents Injuries & Poisonings 0.946 0.9 – 0.995 0.0295 1763 16599 all phecode
979 Adverse drug events and drug allergies Injuries & Poisonings 0.975 0.941 – 1.01 0.172 3448 30885 all phecode
980
Encounter for long-term (current) use of
Encounter for long-term (current) use of antibiotics
 Infectious Diseases 1.04 0.981 – 1.1 0.201 1391 13877 all phecode
985 Toxic effect of other metals Injuries & Poisonings 0.846 0.657 – 1.09 0.193 57 564 all phecode
989
Toxic effect of other substances, chiefly
Toxic effect of other substances, chiefly nonmedicinal as to source
 Injuries & Poisonings 0.928 0.771 – 1.12 0.428 129 1275 all phecode
990 Effects radiation NOS Injuries & Poisonings 1.02 0.99 – 1.06 0.175 3927 31223 all phecode
994 Sepsis and SIRS Injuries & Poisonings 0.964 0.922 – 1.01 0.107 2192 21710 all phecode
994.1 Systemic inflammatory response syndrome (SIRS) Injuries & Poisonings 1.05 0.933 – 1.19 0.392 291 2910 all phecode
994.2 Sepsis Injuries & Poisonings 0.963 0.92 – 1.01 0.107 2086 20666 all phecode
994.21 Septic shock Injuries & Poisonings 0.933 0.86 – 1.01 0.102 627 6260 all phecode
008 Intestinal infection Infectious Diseases 1.01 0.923 – 1.1 0.867 613 3458 exclusion phecode
008.5 Bacterial enteritis Infectious Diseases 1.04 0.901 – 1.21 0.571 213 1491 exclusion phecode
008.52 Intestinal infection due to C. difficile Infectious Diseases 1.04 0.879 – 1.24 0.62 151 1133 exclusion phecode
008.6 Viral Enteritis Infectious Diseases 1.03 0.871 – 1.22 0.73 153 948 exclusion phecode
010 Tuberculosis Infectious Diseases 1.56 1.02 – 2.37 0.0383 27 271 exclusion phecode
031 Diseases due to other mycobacteria Infectious Diseases 0.769 0.477 – 1.24 0.28 24 118 exclusion phecode
038 Septicemia Infectious Diseases 0.927 0.818 – 1.05 0.23 278 2448 exclusion phecode
038.1 Gram negative septicemia Infectious Diseases 0.951 0.726 – 1.24 0.712 62 541 exclusion phecode
038.2 Gram positive septicemia Infectious Diseases 0.689 0.424 – 1.12 0.133 17 223 exclusion phecode
038.3 Bacteremia Infectious Diseases 1.07 0.883 – 1.29 0.503 120 1135 exclusion phecode
041 Bacterial infection NOS Infectious Diseases 0.978 0.907 – 1.05 0.562 843 4149 exclusion phecode
041.1 Staphylococcus infections Infectious Diseases 0.932 0.8 – 1.09 0.368 180 1642 exclusion phecode
041.11 Methicillin sensitive Staphylococcus aureus Infectious Diseases 0.914 0.725 – 1.15 0.449 86 864 exclusion phecode
041.12 Methicillin resistant Staphylococcus aureus Infectious Diseases 0.978 0.779 – 1.23 0.85 77 773 exclusion phecode
041.2 Streptococcus infection Infectious Diseases 0.941 0.812 – 1.09 0.419 199 1692 exclusion phecode
041.21 Rheumatic fever / chorea Infectious Diseases 0.9 0.645 – 1.26 0.535 40 311 exclusion phecode
041.4 E. coli Infectious Diseases 0.988 0.849 – 1.15 0.88 199 1438 exclusion phecode
041.8 H. pylori Infectious Diseases 1.11 0.798 – 1.53 0.543 45 352 exclusion phecode
041.9 Infection with drug-resistant microorganisms Infectious Diseases 0.868 0.618 – 1.22 0.413 39 409 exclusion phecode
053 Herpes zoster Infectious Diseases 1.07 0.954 – 1.2 0.252 399 1480 exclusion phecode
053.1 Herpes zoster with nervous system complications Infectious Diseases 0.875 0.627 – 1.22 0.434 55 226 exclusion phecode
054 Herpes simplex Infectious Diseases 0.98 0.878 – 1.09 0.718 426 1548 exclusion phecode
070 Viral hepatitis Infectious Diseases 1.14 0.905 – 1.44 0.264 92 586 exclusion phecode
070.1 Viral hepatitis A Infectious Diseases 1.13 0.631 – 2.02 0.683 13 73 exclusion phecode
070.2 Viral hepatitis B Infectious Diseases 0.812 0.544 – 1.21 0.309 30 166 exclusion phecode
070.3 Viral hepatitis C Infectious Diseases 1.23 0.875 – 1.72 0.236 45 346 exclusion phecode
070.4 Chronic hepatitis Infectious Diseases 1.24 0.812 – 1.89 0.319 28 147 exclusion phecode
070.9 Hepatitis NOS Infectious Diseases 1.09 0.916 – 1.31 0.321 156 877 exclusion phecode
071 Human immunodeficiency virus [HIV] disease Infectious Diseases 1.21 0.674 – 2.17 0.525 15 79 exclusion phecode
071.1 HIV infection, symptomatic Infectious Diseases 0.967 0.494 – 1.9 0.923 14 56 exclusion phecode
078 Viral warts & HPV Infectious Diseases 1.06 0.975 – 1.14 0.183 841 2514 exclusion phecode
079 Viral infection Infectious Diseases 1.01 0.948 – 1.08 0.736 1568 2771 exclusion phecode
079.1 Varicella infection Infectious Diseases 1.01 0.939 – 1.09 0.762 1011 2649 exclusion phecode
079.2 Infectious mononucleosis Infectious Diseases 0.753 0.52 – 1.09 0.135 39 228 exclusion phecode
079.9 Viremia, NOS Infectious Diseases 0.913 0.767 – 1.09 0.31 172 730 exclusion phecode
080 Postoperative infection Infectious Diseases 1.08 0.952 – 1.23 0.23 269 2968 exclusion phecode
081
Infection/inflammation of internal prosthetic
Infection/inflammation of internal prosthetic device; implant; and graft
 Infectious Diseases 1.12 0.958 – 1.32 0.153 170 1651 exclusion phecode
090
Sexually transmitted infections (not HIV or
Sexually transmitted infections (not HIV or hepatitis)
 Infectious Diseases 0.996 0.861 – 1.15 0.962 206 1202 exclusion phecode
110 Dermatophytosis / Dermatomycosis Infectious Diseases 0.986 0.91 – 1.07 0.735 791 3037 exclusion phecode
110.1 Dermatophytosis Infectious Diseases 0.993 0.912 – 1.08 0.864 724 2781 exclusion phecode
110.11 Dermatophytosis of nail Infectious Diseases 0.983 0.884 – 1.09 0.755 464 1862 exclusion phecode
110.12 Althete's foot Infectious Diseases 0.958 0.803 – 1.14 0.634 174 833 exclusion phecode
110.13 Dermatophytosis of the body Infectious Diseases 1.04 0.867 – 1.24 0.702 156 718 exclusion phecode
110.2 Dermatomycoses Infectious Diseases 0.915 0.72 – 1.16 0.47 86 425 exclusion phecode
112 Candidiasis Infectious Diseases 0.955 0.878 – 1.04 0.291 670 3412 exclusion phecode
112.3 Candidiasis of skin and nails Infectious Diseases 1.01 0.821 – 1.25 0.909 109 877 exclusion phecode
117 Mycoses Infectious Diseases 0.933 0.745 – 1.17 0.547 92 602 exclusion phecode
117.1 Histoplasmosis Infectious Diseases 0.883 0.516 – 1.51 0.649 17 97 exclusion phecode
117.4 Aspergillosis Infectious Diseases 1.08 0.676 – 1.71 0.758 23 135 exclusion phecode
130 Spirochetal infection Infectious Diseases 0.919 0.647 – 1.31 0.639 41 188 exclusion phecode
130.1 Lyme disease Infectious Diseases 0.611 0.401 – 0.933 0.0224 31 150 exclusion phecode
131 Protozoan infection Infectious Diseases 0.973 0.534 – 1.77 0.928 13 92 exclusion phecode
132 Infestation (lice, mites) Infectious Diseases 1.24 0.861 – 1.79 0.246 35 222 exclusion phecode
134 Helminthiases Infectious Diseases 0.8 0.446 – 1.44 0.456 23 97 exclusion phecode
134.1 Intestinal helminthiases Infectious Diseases 0.665 0.304 – 1.45 0.307 16 63 exclusion phecode
136 Other infectious and parasitic diseases Infectious Diseases 0.953 0.87 – 1.04 0.294 558 3682 exclusion phecode
145 Cancer of mouth Neoplasms 0.908 0.719 – 1.15 0.419 76 1363 exclusion phecode
145.1 Cancer of lip Neoplasms 0.351 0.0971 – 1.27 0.111 3 65 exclusion phecode
145.2 Cancer of tongue Neoplasms 0.903 0.64 – 1.27 0.558 34 528 exclusion phecode
145.3 Cancer of major salivary glands Neoplasms 0.905 0.572 – 1.43 0.67 17 342 exclusion phecode
145.4 Cancer of the gums Neoplasms 0.755 0.364 – 1.57 0.45 3 204 exclusion phecode
145.5 Cancer of the mouth floor Neoplasms 0.623 0.332 – 1.17 0.141 12 178 exclusion phecode
149 Cancer of larynx, pharynx, nasal cavities Neoplasms 0.933 0.741 – 1.17 0.551 80 1141 exclusion phecode
149.1 Cancer of oropharynx Neoplasms 0.979 0.669 – 1.43 0.912 29 255 exclusion phecode
149.2 Cancer of nasopharynx Neoplasms 1.22 0.593 – 2.5 0.593 11 109 exclusion phecode
149.3 Cancer of hypopharynx Neoplasms 1.23 0.622 – 2.42 0.555 8 71 exclusion phecode
149.4 Cancer of larynx Neoplasms 0.873 0.541 – 1.41 0.579 16 246 exclusion phecode
149.5
Hx of malignant neoplasm of oral cavity and
Hx of malignant neoplasm of oral cavity and pharynx
 Neoplasms 0.838 0.608 – 1.16 0.283 43 474 exclusion phecode
149.9 Cancer of of nasal cavities Neoplasms 0.871 0.532 – 1.43 0.583 14 264 exclusion phecode
150 Cancer of esophagus Neoplasms 0.97 0.654 – 1.44 0.882 29 315 exclusion phecode
151 Cancer of stomach Neoplasms 1.06 0.731 – 1.53 0.773 33 420 exclusion phecode
153 Colorectal cancer Neoplasms 1.11 0.933 – 1.31 0.245 170 1121 exclusion phecode
153.2 Colon cancer Neoplasms 1.15 0.947 – 1.39 0.16 136 853 exclusion phecode
153.3
Malignant neoplasm of rectum, rectosigmoid
Malignant neoplasm of rectum, rectosigmoid junction, and anus
 Neoplasms 1.11 0.872 – 1.41 0.399 92 637 exclusion phecode
155 Cancer of liver and intrahepatic bile duct Neoplasms 0.719 0.505 – 1.02 0.0672 36 475 exclusion phecode
155.1 Malignant neoplasm of liver, primary Neoplasms 0.755 0.481 – 1.19 0.222 22 321 exclusion phecode
157 Pancreatic cancer Neoplasms 1.03 0.749 – 1.42 0.845 42 509 exclusion phecode
158
Neoplasm of unspecified nature of digestive
Neoplasm of unspecified nature of digestive system
 Neoplasms 0.944 0.821 – 1.09 0.422 247 1650 exclusion phecode
159
Malignant neoplasm of other and ill-defined
Malignant neoplasm of other and ill-defined sites within the digestive organs and peritoneum
 Neoplasms 1.01 0.859 – 1.18 0.922 178 1781 exclusion phecode
159.2
Malignant neoplasm of small intestine
Malignant neoplasm of small intestine, including duodenum
 Neoplasms 1.17 0.753 – 1.81 0.49 16 217 exclusion phecode
159.3
Malignant neoplasm of gallbladder and
Malignant neoplasm of gallbladder and extrahepatic bile ducts
 Neoplasms 1.29 0.684 – 2.43 0.432 8 176 exclusion phecode
159.4
Malignant neoplasm of retroperitoneum and
Malignant neoplasm of retroperitoneum and peritoneum
 Neoplasms 1.16 0.807 – 1.66 0.428 31 354 exclusion phecode
164 Cancer of intrathoracic organs Neoplasms 1.42 0.856 – 2.35 0.175 15 156 exclusion phecode
165 Cancer within the respiratory system Neoplasms 0.983 0.803 – 1.2 0.865 107 1347 exclusion phecode
165.1 Cancer of bronchus; lung Neoplasms 1.05 0.842 – 1.3 0.678 93 1105 exclusion phecode
170 Cancer of bone and connective tissue Neoplasms 0.978 0.81 – 1.18 0.82 124 1888 exclusion phecode
170.1 Bone cancer Neoplasms 0.914 0.677 – 1.23 0.556 48 806 exclusion phecode
170.2 Cancer of connective tissue Neoplasms 0.974 0.772 – 1.23 0.822 85 1321 exclusion phecode
172 Skin cancer Neoplasms 1.01 0.933 – 1.08 0.895 996 3559 exclusion phecode
172.1 Melanomas of skin, dx or hx Neoplasms 1.01 0.928 – 1.1 0.781 677 3224 exclusion phecode
172.11 Melanomas of skin Neoplasms 1.02 0.889 – 1.17 0.788 236 2544 exclusion phecode
172.2 Other non-epithelial cancer of skin Neoplasms 1.02 0.943 – 1.1 0.615 886 3305 exclusion phecode
172.21 Basal cell carcinoma Neoplasms 1.02 0.931 – 1.12 0.653 591 2644 exclusion phecode
172.22 Squamous cell carcinoma Neoplasms 1.06 0.934 – 1.21 0.353 271 1752 exclusion phecode
172.3 Carcinoma in situ of skin Neoplasms 0.957 0.831 – 1.1 0.541 245 1316 exclusion phecode
173 Neoplasm of uncertain behavior of skin Neoplasms 1.01 0.905 – 1.12 0.921 439 2240 exclusion phecode
174 Breast cancer Neoplasms 1.06 0.964 – 1.15 0.245 665 2135 exclusion phecode
174.1 Breast cancer [female] Neoplasms 1.06 0.97 – 1.17 0.192 639 2090 exclusion phecode
174.11 Malignant neoplasm of female breast Neoplasms 1.08 0.981 – 1.18 0.119 625 2074 exclusion phecode
174.3 Neoplasm of uncertain behavior of breast Neoplasms 1.13 0.857 – 1.49 0.385 73 328 exclusion phecode
175 Acquired absence of breast Neoplasms 1.02 0.873 – 1.2 0.769 196 918 exclusion phecode
180 Cervical cancer and dysplasia Neoplasms 1.13 0.992 – 1.28 0.0659 290 1511 exclusion phecode
180.1 Cervical cancer Neoplasms 1.32 0.983 – 1.77 0.0645 49 613 exclusion phecode
180.3
Cervical intraepithelial neoplasia [CIN]
Cervical intraepithelial neoplasia [CIN] [Cervical dysplasia]
 Neoplasms 1.1 0.959 – 1.26 0.173 262 1098 exclusion phecode
182 Malignant neoplasm of uterus Neoplasms 1.14 0.919 – 1.42 0.232 91 1107 exclusion phecode
184 Cancer of other female genital organs Neoplasms 1.18 1.02 – 1.37 0.0298 196 1817 exclusion phecode
184.1
Malignant neoplasm of ovary and other uterine
Malignant neoplasm of ovary and other uterine adnexa
 Neoplasms 1.18 0.958 – 1.46 0.119 95 927 exclusion phecode
184.11 Malignant neoplasm of ovary Neoplasms 1.12 0.882 – 1.41 0.359 68 685 exclusion phecode
184.2
Cancer of other female genital organs
Cancer of other female genital organs (excluding uterus and ovary)
 Neoplasms 1.06 0.869 – 1.29 0.568 113 981 exclusion phecode
185 Cancer of prostate Neoplasms 1.11 0.9 – 1.37 0.33 149 464 exclusion phecode
187 Cancer of other male genital organs Neoplasms 1.62 1.03 – 2.55 0.0388 21 168 exclusion phecode
187.1
Malignant neoplasm of unspecified male genital
Malignant neoplasm of unspecified male genital organ
 Neoplasms 4.2 0.858 – 20.6 0.0766 4 55 exclusion phecode
187.2 Malignant neoplasm of testis Neoplasms 1.28 0.727 – 2.26 0.39 14 90 exclusion phecode
187.8
Neoplasm of uncertain behavior of male genital
Neoplasm of uncertain behavior of male genital organs
 Neoplasms 0.51 0.146 – 1.78 0.291 5 21 exclusion phecode
189
Cancer of urinary organs (incl. kidney and
Cancer of urinary organs (incl. kidney and bladder)
 Neoplasms 0.87 0.743 – 1.02 0.0836 178 2359 exclusion phecode
189.1 Cancer of kidney and renal pelvis Neoplasms 0.824 0.662 – 1.03 0.0837 89 1453 exclusion phecode
189.11 Malignant neoplasm of kidney, except pelvis Neoplasms 0.774 0.607 – 0.985 0.0374 74 1220 exclusion phecode
189.12 Malignant neoplasm of renal pelvis Neoplasms 1.07 0.642 – 1.77 0.806 16 218 exclusion phecode
189.2 Cancer of bladder Neoplasms 0.946 0.768 – 1.16 0.599 103 1380 exclusion phecode
189.21 Malignant neoplasm of bladder Neoplasms 0.961 0.765 – 1.21 0.734 84 1238 exclusion phecode
189.4 Malignant neoplasm of other urinary organs Neoplasms 0.932 0.633 – 1.37 0.723 25 539 exclusion phecode
190 Cancer of eye Neoplasms 1.22 0.65 – 2.31 0.53 14 153 exclusion phecode
191
Manlignant and unknown neoplasms of brain and
Manlignant and unknown neoplasms of brain and nervous system
 Neoplasms 0.976 0.779 – 1.22 0.836 86 1069 exclusion phecode
191.1 Cancer of brain and nervous system Neoplasms 0.808 0.599 – 1.09 0.164 50 676 exclusion phecode
191.11 Cancer of brain Neoplasms 0.796 0.571 – 1.11 0.176 41 563 exclusion phecode
193 Thyroid cancer Neoplasms 0.9 0.727 – 1.12 0.337 89 1149 exclusion phecode
194 Cancer of other endocrine glands Neoplasms 0.804 0.63 – 1.03 0.0808 77 721 exclusion phecode
195 Cancer, suspected or other Neoplasms 1.01 0.949 – 1.08 0.728 1881 2782 exclusion phecode
195.1 Malignant neoplasm, other Neoplasms 1.01 0.948 – 1.08 0.729 1860 2782 exclusion phecode
195.3 Malignant neoplasm of head, face, and neck Neoplasms 1.02 0.815 – 1.28 0.863 75 846 exclusion phecode
196 Radiotherapy Neoplasms 1.13 1 – 1.26 0.0416 369 1922 exclusion phecode
197 Chemotherapy Neoplasms 1.03 0.938 – 1.14 0.516 545 2469 exclusion phecode
198 Secondary malignant neoplasm Neoplasms 0.966 0.869 – 1.07 0.514 441 2434 exclusion phecode
198.1 Secondary malignancy of lymph nodes Neoplasms 0.966 0.852 – 1.1 0.594 282 2245 exclusion phecode
198.2 Secondary malignancy of respiratory organs Neoplasms 0.929 0.741 – 1.17 0.525 80 980 exclusion phecode
198.3
Secondary malignant neoplasm of digestive
Secondary malignant neoplasm of digestive systems
 Neoplasms 1.07 0.852 – 1.34 0.564 78 950 exclusion phecode
198.4 Secondary malignant neoplasm of liver Neoplasms 1.04 0.811 – 1.34 0.746 67 751 exclusion phecode
198.5 Secondary malignancy of brain/spine Neoplasms 0.795 0.568 – 1.11 0.181 35 628 exclusion phecode
198.6 Secondary malignancy of bone Neoplasms 0.765 0.58 – 1.01 0.0564 60 801 exclusion phecode
198.7 Secondary malignant neoplasm of skin Neoplasms 1.13 0.754 – 1.7 0.55 24 331 exclusion phecode
199 Neoplasm of uncertain behavior Neoplasms 1.03 0.946 – 1.12 0.495 771 2735 exclusion phecode
199.4 Neurofibromatosis Neoplasms 0.704 0.329 – 1.51 0.366 10 94 exclusion phecode
200 Myeloproliferative disease Neoplasms 0.872 0.733 – 1.04 0.126 148 1167 exclusion phecode
200.1 Polycythemia vera Neoplasms 0.916 0.611 – 1.37 0.672 29 192 exclusion phecode
201 Hodgkin's disease Neoplasms 1.05 0.662 – 1.67 0.829 23 174 exclusion phecode
202 Cancer of other lymphoid, histiocytic tissue Neoplasms 0.973 0.835 – 1.13 0.727 187 1687 exclusion phecode
202.2 Non-Hodgkins lymphoma Neoplasms 0.942 0.799 – 1.11 0.474 163 1447 exclusion phecode
202.21 Nodular lymphoma Neoplasms 0.978 0.802 – 1.19 0.822 111 847 exclusion phecode
202.22 Reticulosarcoma Neoplasms 0.958 0.546 – 1.68 0.882 11 151 exclusion phecode
202.24 Large cell lymphoma Neoplasms 0.999 0.533 – 1.87 0.997 11 123 exclusion phecode
204 Leukemia Neoplasms 0.931 0.744 – 1.17 0.536 85 687 exclusion phecode
204.1 Lymphoid leukemia Neoplasms 0.774 0.518 – 1.15 0.209 25 233 exclusion phecode
204.11 Lymphoid leukemia, acute Neoplasms 0.72 0.333 – 1.56 0.403 10 45 exclusion phecode
204.12 Lymphoid leukemia, chronic Neoplasms 0.766 0.492 – 1.19 0.237 17 180 exclusion phecode
204.2 Myeloid leukemia Neoplasms 1.19 0.847 – 1.68 0.315 34 271 exclusion phecode
204.21 Myeloid leukemia, acute Neoplasms 1.44 0.931 – 2.24 0.101 20 157 exclusion phecode
204.22 Myeloid leukemia, chronic Neoplasms 2.03 0.939 – 4.37 0.0721 11 63 exclusion phecode
204.4 Multiple myeloma Neoplasms 0.751 0.481 – 1.17 0.21 23 234 exclusion phecode
208 Benign neoplasm of colon Neoplasms 1.04 0.977 – 1.1 0.236 2087 2965 exclusion phecode
209 Neuroendocrine tumors Neoplasms 1.23 0.833 – 1.82 0.297 25 294 exclusion phecode
210 Benign neoplasm of lip, oral cavity, and pharynx Neoplasms 1.04 0.888 – 1.22 0.61 163 1824 exclusion phecode
211
Benign neoplasm of other parts of digestive
Benign neoplasm of other parts of digestive system
 Neoplasms 1 0.936 – 1.07 0.995 1222 3724 exclusion phecode
212
Benign neoplasm of respiratory and
Benign neoplasm of respiratory and intrathoracic organs
 Neoplasms 0.72 0.615 – 0.843 4.38e-05 176 1792 exclusion phecode
213 Benign neoplasm of bone and articular cartilage Neoplasms 0.964 0.81 – 1.15 0.683 158 1017 exclusion phecode
214 Lipoma Neoplasms 0.974 0.856 – 1.11 0.686 277 1687 exclusion phecode
214.1 Lipoma of skin and subcutaneous tissue Neoplasms 0.97 0.821 – 1.15 0.725 176 1037 exclusion phecode
215
Other benign neoplasm of connective and other
Other benign neoplasm of connective and other soft tissue
 Neoplasms 0.999 0.918 – 1.09 0.987 641 4149 exclusion phecode
216 Benign neoplasm of skin Neoplasms 0.976 0.922 – 1.03 0.407 2276 2882 exclusion phecode
216.1 Screening for malignant neoplasms of the skin Neoplasms 0.93 0.675 – 1.28 0.659 53 190 exclusion phecode
217 Vascular hamartomas and non-neoplastic nevi Neoplasms 1.06 0.963 – 1.18 0.221 516 1726 exclusion phecode
217.1 Nevus, non-neoplastic Neoplasms 1.05 0.947 – 1.16 0.365 500 1652 exclusion phecode
218 Benign neoplasm of uterus Neoplasms 1.07 0.998 – 1.16 0.057 1117 2301 exclusion phecode
218.1 Uterine leiomyoma Neoplasms 1.07 0.963 – 1.18 0.217 485 2180 exclusion phecode
218.2 Other benign neoplasm of uterus Neoplasms 1.1 1.01 – 1.19 0.0225 875 2237 exclusion phecode
220 Benign neoplasm of ovary Neoplasms 1.11 0.945 – 1.31 0.202 170 1041 exclusion phecode
221 Benign neoplasm of other female genital organs Neoplasms 1.11 0.989 – 1.24 0.077 368 1805 exclusion phecode
222 Benign neoplasm of male genital organs Neoplasms 1.05 0.821 – 1.35 0.682 74 570 exclusion phecode
223
Benign neoplasm of kidney and other urinary
Benign neoplasm of kidney and other urinary organs
 Neoplasms 1.13 0.924 – 1.37 0.237 122 815 exclusion phecode
224 Benign neoplasm of eye Neoplasms 1.01 0.845 – 1.21 0.905 150 837 exclusion phecode
224.1 Benign neoplasm of eye, uveal Neoplasms 0.974 0.805 – 1.18 0.789 137 693 exclusion phecode
225
Benign neoplasm of brain and other parts of
Benign neoplasm of brain and other parts of nervous system
 Neoplasms 0.979 0.808 – 1.19 0.831 124 1344 exclusion phecode
225.1
Benign neoplasm of brain, cranial nerves
Benign neoplasm of brain, cranial nerves, meninges
 Neoplasms 0.972 0.78 – 1.21 0.798 94 1075 exclusion phecode
225.2 Benign neoplasm of spinal cord, meninges Neoplasms 0.803 0.562 – 1.15 0.225 36 329 exclusion phecode
226 Benign neoplasm of thyroid glands Neoplasms 0.894 0.772 – 1.04 0.137 208 1825 exclusion phecode
227
Benign neoplasm of other endocrine glands and
Benign neoplasm of other endocrine glands and related structures
 Neoplasms 1.09 0.933 – 1.28 0.271 171 2053 exclusion phecode
227.1 Benign neoplasm of adrenal gland Neoplasms 1.22 0.924 – 1.6 0.163 51 560 exclusion phecode
227.2 Benign neoplasm of parathyroid gland Neoplasms 0.904 0.73 – 1.12 0.356 92 1025 exclusion phecode
227.3
Benign neoplasm of pituitary gland and
Benign neoplasm of pituitary gland and craniopharyngeal duct (pouch)
 Neoplasms 1.41 0.956 – 2.09 0.0825 25 498 exclusion phecode
228 Hemangioma and lymphangioma, any site Neoplasms 1.06 0.963 – 1.17 0.231 547 2534 exclusion phecode
228.1 Hemangioma of skin and subcutaneous tissue Neoplasms 1.04 0.924 – 1.16 0.545 386 1664 exclusion phecode
229 Benign neoplasm of unspecified sites Neoplasms 1.08 1 – 1.17 0.0474 745 4040 exclusion phecode
229.1 Benign neoplasm of lymph nodes Neoplasms 1.05 0.951 – 1.16 0.327 434 3754 exclusion phecode
240 Simple and unspecified goiter Endocrine/metabolic 0.976 0.847 – 1.12 0.731 237 1459 exclusion phecode
241 Nontoxic nodular goiter Endocrine/metabolic 0.933 0.848 – 1.03 0.16 523 2775 exclusion phecode
241.1 Nontoxic uninodular goiter Endocrine/metabolic 0.91 0.819 – 1.01 0.0787 427 2565 exclusion phecode
241.2 Nontoxic multinodular goiter Endocrine/metabolic 0.951 0.825 – 1.1 0.483 233 1781 exclusion phecode
242 Thyrotoxicosis with or without goiter Endocrine/metabolic 0.943 0.831 – 1.07 0.368 292 1835 exclusion phecode
242.1 Graves' disease Endocrine/metabolic 0.949 0.757 – 1.19 0.647 100 690 exclusion phecode
242.2 Toxic multinodular goiter Endocrine/metabolic 1.19 0.782 – 1.82 0.413 23 177 exclusion phecode
242.3 Exophthalmos Endocrine/metabolic 0.827 0.626 – 1.09 0.18 56 358 exclusion phecode
242.31 Thyrotoxic exophthalmos Endocrine/metabolic 0.953 0.641 – 1.42 0.814 28 184 exclusion phecode
244 Hypothyroidism Endocrine/metabolic 0.98 0.915 – 1.05 0.558 1270 3352 exclusion phecode
244.1 Secondary hypothyroidism Endocrine/metabolic 0.935 0.819 – 1.07 0.321 250 2129 exclusion phecode
244.2 Acquired hypothyroidism Endocrine/metabolic 0.947 0.828 – 1.08 0.421 254 1626 exclusion phecode
244.4 Hypothyroidism NOS Endocrine/metabolic 0.987 0.92 – 1.06 0.702 1224 3322 exclusion phecode
245 Thyroiditis Endocrine/metabolic 1.04 0.881 – 1.24 0.626 166 1167 exclusion phecode
245.2 Chronic thyroiditis Endocrine/metabolic 1.04 0.867 – 1.25 0.673 136 1029 exclusion phecode
245.21 Chronic lymphocytic thyroiditis Endocrine/metabolic 1.04 0.869 – 1.25 0.669 136 1016 exclusion phecode
246 Other disorders of thyroid Endocrine/metabolic 0.957 0.887 – 1.03 0.263 967 3192 exclusion phecode
246.2 Thyroid cyst Endocrine/metabolic 0.981 0.627 – 1.53 0.931 26 117 exclusion phecode
246.7 Abnormal results of function study of thyroid Endocrine/metabolic 0.971 0.836 – 1.13 0.705 213 1212 exclusion phecode
249 Secondary diabetes mellitus Endocrine/metabolic 0.889 0.718 – 1.1 0.28 146 720 exclusion phecode
250 Diabetes mellitus Endocrine/metabolic 1.05 0.982 – 1.12 0.158 1962 3223 exclusion phecode
250.1 Type 1 diabetes Endocrine/metabolic 0.93 0.8 – 1.08 0.345 536 1157 exclusion phecode
250.11 Type 1 diabetes with ketoacidosis Endocrine/metabolic 0.787 0.557 – 1.11 0.176 105 86 exclusion phecode
250.12 Type 1 diabetes with renal manifestations Endocrine/metabolic 0.889 0.692 – 1.14 0.357 166 267 exclusion phecode
250.13 Type 1 diabetes with ophthalmic manifestations Endocrine/metabolic 0.85 0.664 – 1.09 0.198 245 292 exclusion phecode
250.14 Type 1 diabetes with neurological manifestations Endocrine/metabolic 0.796 0.625 – 1.01 0.0634 193 246 exclusion phecode
250.15
Diabetes type 1 with peripheral circulatory
Diabetes type 1 with peripheral circulatory disorders
 Endocrine/metabolic 0.867 0.562 – 1.34 0.519 47 84 exclusion phecode
250.2 Type 2 diabetes Endocrine/metabolic 1 0.92 – 1.09 0.939 1026 3064 exclusion phecode
250.21 Type 2 diabetes with ketoacidosis Endocrine/metabolic 0.8 0.569 – 1.12 0.198 81 118 exclusion phecode
250.22 Type 2 diabetes with renal manifestations Endocrine/metabolic 0.973 0.811 – 1.17 0.768 169 1283 exclusion phecode
250.23 Type 2 diabetes with ophthalmic manifestations Endocrine/metabolic 0.856 0.717 – 1.02 0.0861 280 984 exclusion phecode
250.24 Type 2 diabetes with neurological manifestations Endocrine/metabolic 0.891 0.757 – 1.05 0.163 278 1601 exclusion phecode
250.25
Diabetes type 2 with peripheral circulatory
Diabetes type 2 with peripheral circulatory disorders
 Endocrine/metabolic 0.864 0.635 – 1.17 0.349 62 522 exclusion phecode
250.3 Insulin pump user Endocrine/metabolic 0.952 0.824 – 1.1 0.5 476 2026 exclusion phecode
250.4 Abnormal glucose Endocrine/metabolic 1.08 1.01 – 1.16 0.0242 1632 3163 exclusion phecode
250.41 Impaired fasting glucose Endocrine/metabolic 1.08 0.962 – 1.21 0.191 400 1853 exclusion phecode
250.42 Other abnormal glucose Endocrine/metabolic 1.08 1.01 – 1.16 0.0276 1446 3118 exclusion phecode
250.5 Glycosuria or Acetonuria Endocrine/metabolic 1.07 0.647 – 1.76 0.801 25 120 exclusion phecode
250.6 Polyneuropathy in diabetes Endocrine/metabolic 0.798 0.668 – 0.955 0.0135 256 1252 exclusion phecode
250.7 Diabetic retinopathy Endocrine/metabolic 0.91 0.792 – 1.05 0.189 318 1029 exclusion phecode
251 Other disorders of pancreatic internal secretion Endocrine/metabolic 1.03 0.879 – 1.2 0.727 195 1049 exclusion phecode
251.1 Hypoglycemia Endocrine/metabolic 0.96 0.813 – 1.13 0.634 271 870 exclusion phecode
252 Disorders of parathyroid gland Endocrine/metabolic 0.988 0.884 – 1.1 0.831 368 2743 exclusion phecode
252.1 Hyperparathyroidism Endocrine/metabolic 0.974 0.867 – 1.09 0.656 342 2549 exclusion phecode
252.2 Hypoparathyroidism Endocrine/metabolic 0.954 0.752 – 1.21 0.695 75 615 exclusion phecode
253
Disorders of the pituitary gland and its
Disorders of the pituitary gland and its hypothalamic control
 Endocrine/metabolic 0.923 0.744 – 1.14 0.464 98 918 exclusion phecode
253.1 Pituitary hyperfunction Endocrine/metabolic 0.865 0.573 – 1.31 0.49 27 335 exclusion phecode
253.11 Acromegaly and gigantism Endocrine/metabolic 0.247 0.0476 – 1.28 0.0956 2 87 exclusion phecode
253.2 Pituitary hypofunction Endocrine/metabolic 0.859 0.523 – 1.41 0.549 14 194 exclusion phecode
253.3 Diabetes insipidus Endocrine/metabolic 0.894 0.503 – 1.59 0.704 10 103 exclusion phecode
253.4 Anterior pituitary disorders Endocrine/metabolic 0.763 0.421 – 1.38 0.374 14 102 exclusion phecode
253.7 Other disorders of neurohypophysis Endocrine/metabolic 0.878 0.526 – 1.47 0.62 24 93 exclusion phecode
255 Disorders of adrenal glands Endocrine/metabolic 0.964 0.831 – 1.12 0.624 204 1747 exclusion phecode
255.1 Adrenal hyperfunction Endocrine/metabolic 0.912 0.669 – 1.24 0.56 46 460 exclusion phecode
255.11 Cushing's syndrome Endocrine/metabolic 0.92 0.573 – 1.48 0.731 18 229 exclusion phecode
255.12 Hyperaldosteronism Endocrine/metabolic 0.832 0.441 – 1.57 0.568 10 157 exclusion phecode
255.2 Adrenal hypofunction Endocrine/metabolic 1.06 0.857 – 1.3 0.605 103 757 exclusion phecode
255.21 Glucocorticoid deficiency Endocrine/metabolic 1.06 0.855 – 1.32 0.581 99 709 exclusion phecode
256 Ovarian dysfunction Endocrine/metabolic 1.07 0.928 – 1.23 0.362 231 1520 exclusion phecode
256.4 Polycystic ovaries Endocrine/metabolic 1.16 0.96 – 1.41 0.122 121 975 exclusion phecode
257 Testicular dysfunction Endocrine/metabolic 1.06 0.827 – 1.35 0.66 79 494 exclusion phecode
257.1 Testicular hypofunction Endocrine/metabolic 1.04 0.815 – 1.33 0.748 78 475 exclusion phecode
258 Iatrogenic endocrine disorders Endocrine/metabolic 0.63 0.339 – 1.17 0.143 13 97 exclusion phecode
258.1 Postablative ovarian failure Endocrine/metabolic 0.678 0.42 – 1.09 0.112 23 152 exclusion phecode
259 Other endocrine disorders Endocrine/metabolic 1.03 0.883 – 1.21 0.672 198 1201 exclusion phecode
260 Protein-calorie malnutrition Endocrine/metabolic 0.99 0.878 – 1.12 0.875 309 2245 exclusion phecode
260.1 Cachexia Endocrine/metabolic 1.56 1.03 – 2.34 0.0344 28 208 exclusion phecode
260.2 severe protein-calorie malnutrition Endocrine/metabolic 1.04 0.882 – 1.24 0.619 158 1348 exclusion phecode
260.22 Nutritional marasmus Endocrine/metabolic 1.13 0.857 – 1.49 0.385 58 529 exclusion phecode
260.3 Adult failure to thrive Endocrine/metabolic 1.18 0.907 – 1.53 0.218 61 515 exclusion phecode
260.6 Anorexia Endocrine/metabolic 0.932 0.764 – 1.14 0.483 119 773 exclusion phecode
260.7 Polyphagia Endocrine/metabolic 1.44 0.782 – 2.65 0.242 12 121 exclusion phecode
261 Vitamin deficiency Endocrine/metabolic 1.05 0.985 – 1.12 0.134 1671 3132 exclusion phecode
261.1 Vitamin A deficiency Endocrine/metabolic 0.952 0.429 – 2.11 0.903 6 86 exclusion phecode
261.2 Vitamin B-complex deficiencies Endocrine/metabolic 1.13 0.948 – 1.34 0.173 165 899 exclusion phecode
261.4 Vitamin D deficiency Endocrine/metabolic 1.04 0.981 – 1.11 0.175 1606 3134 exclusion phecode
261.41 Rickets or osteomalacia Endocrine/metabolic 1 0.548 – 1.83 0.998 14 62 exclusion phecode
262 Mineral deficiency NEC Endocrine/metabolic 1.07 0.929 – 1.24 0.341 231 1301 exclusion phecode
263 Other nutritional deficiency Endocrine/metabolic 0.982 0.869 – 1.11 0.775 316 1700 exclusion phecode
264 Lack of normal physiological development Endocrine/metabolic 1.11 0.776 – 1.58 0.576 28 177 exclusion phecode
264.2 Failure to thrive (childhood) Endocrine/metabolic 1.5 0.934 – 2.4 0.0941 17 97 exclusion phecode
264.9
Lack of normal physiological development
Lack of normal physiological development, unspecified
 Endocrine/metabolic 1.05 0.553 – 2.01 0.872 9 62 exclusion phecode
269 Proteinuria Endocrine/metabolic 0.944 0.827 – 1.08 0.397 261 1601 exclusion phecode
270
Disorders of protein plasma/amino-acid
Disorders of protein plasma/amino-acid transport and metabolism
 Endocrine/metabolic 0.874 0.729 – 1.05 0.146 152 1085 exclusion phecode
270.1 Disturbances of amino-acid transport Endocrine/metabolic 1.14 0.743 – 1.74 0.553 23 210 exclusion phecode
270.11
Disturbances of sulphur-bearing amino-acid
Disturbances of sulphur-bearing amino-acid metabolism
 Endocrine/metabolic 1.12 0.7 – 1.79 0.64 20 178 exclusion phecode
270.2 Disorders of amino-acid metabolism Endocrine/metabolic 1.02 0.556 – 1.89 0.938 12 122 exclusion phecode
270.3 Disorders of plasma protein metabolism Endocrine/metabolic 0.826 0.676 – 1.01 0.0608 124 812 exclusion phecode
270.32 Paraproteinemia Endocrine/metabolic 0.829 0.619 – 1.11 0.208 65 453 exclusion phecode
270.33 Amyloidosis Endocrine/metabolic 1.46 0.673 – 3.16 0.339 7 89 exclusion phecode
270.34 Alpha-1-antitrypsin deficiency Endocrine/metabolic 1.01 0.467 – 2.18 0.984 10 79 exclusion phecode
270.38
Other specified disorders of plasma protein
Other specified disorders of plasma protein metabolism
 Endocrine/metabolic 0.748 0.557 – 1.01 0.0541 48 319 exclusion phecode
271
Disorders of carbohydrate transport and
Disorders of carbohydrate transport and metabolism
 Endocrine/metabolic 1.11 1.02 – 1.21 0.018 638 3388 exclusion phecode
271.3
Intestinal disaccharidase deficiencies and
Intestinal disaccharidase deficiencies and disaccharide malabsorption
 Endocrine/metabolic 1.11 1.02 – 1.21 0.0203 627 3319 exclusion phecode
271.9
Other disorders of carbohydrate transport and
Other disorders of carbohydrate transport and metabolism
 Endocrine/metabolic 0.748 0.426 – 1.31 0.311 17 121 exclusion phecode
272 Disorders of lipoid metabolism Endocrine/metabolic 0.946 0.889 – 1.01 0.0851 2590 2592 exclusion phecode
272.1 Hyperlipidemia Endocrine/metabolic 0.948 0.89 – 1.01 0.0943 2579 2590 exclusion phecode
272.11 Hypercholesterolemia Endocrine/metabolic 0.953 0.873 – 1.04 0.283 927 2247 exclusion phecode
272.12 Hyperglyceridemia Endocrine/metabolic 0.85 0.699 – 1.03 0.103 116 1097 exclusion phecode
272.13 Mixed hyperlipidemia Endocrine/metabolic 0.993 0.895 – 1.1 0.899 587 1861 exclusion phecode
272.9 Unspecified disorder of lipoid metabolism Endocrine/metabolic 1.03 0.797 – 1.34 0.799 78 294 exclusion phecode
274 Gout and other crystal arthropathies Endocrine/metabolic 0.965 0.844 – 1.1 0.608 247 2143 exclusion phecode
274.1 Gout Endocrine/metabolic 0.952 0.825 – 1.1 0.498 217 2031 exclusion phecode
274.11 Gouty arthropathy Endocrine/metabolic 1 0.834 – 1.21 0.978 134 996 exclusion phecode
274.2 Crystal arthropathies Endocrine/metabolic 1.25 0.886 – 1.78 0.201 44 246 exclusion phecode
274.21 Chondrocalcinosis Endocrine/metabolic 1.22 0.845 – 1.76 0.289 41 228 exclusion phecode
275 Disorders of mineral metabolism Endocrine/metabolic 0.969 0.891 – 1.05 0.46 688 3994 exclusion phecode
275.1 Disorders of iron metabolism Hematopoietic 1.18 0.808 – 1.73 0.388 30 255 exclusion phecode
275.11 Hereditary hemochromatosis Hematopoietic 1.35 0.692 – 2.65 0.375 11 113 exclusion phecode
275.2 Disorders of copper metabolism Endocrine/metabolic 0.384 0.163 – 0.906 0.0289 7 77 exclusion phecode
275.3 Disorders of magnesium metabolism Endocrine/metabolic 0.996 0.833 – 1.19 0.964 138 1263 exclusion phecode
275.5 Disorders of calcium/phosphorus metabolism Endocrine/metabolic 0.966 0.881 – 1.06 0.47 556 3543 exclusion phecode
275.51 Hypocalcemia Endocrine/metabolic 1.06 0.87 – 1.29 0.57 124 957 exclusion phecode
275.53 Disorders of phosphorus metabolism Endocrine/metabolic 1.04 0.883 – 1.23 0.632 168 1348 exclusion phecode
275.6 Hypercalcemia Endocrine/metabolic 1 0.888 – 1.13 0.973 317 1850 exclusion phecode
276
Disorders of fluid, electrolyte, and acid-base
Disorders of fluid, electrolyte, and acid-base balance
 Endocrine/metabolic 0.976 0.915 – 1.04 0.457 1376 3779 exclusion phecode
276.1 Electrolyte imbalance Endocrine/metabolic 0.947 0.879 – 1.02 0.157 971 3550 exclusion phecode
276.11 Hyperosmolality and/or hypernatremia Endocrine/metabolic 0.778 0.609 – 0.994 0.0445 74 493 exclusion phecode
276.12 Hyposmolality and/or hyponatremia Endocrine/metabolic 0.913 0.818 – 1.02 0.106 389 2200 exclusion phecode
276.13 Hyperpotassemia Endocrine/metabolic 0.994 0.897 – 1.1 0.904 452 2511 exclusion phecode
276.14 Hypopotassemia Endocrine/metabolic 0.901 0.803 – 1.01 0.0756 355 2305 exclusion phecode
276.4 Acid-base balance disorder Endocrine/metabolic 0.883 0.779 – 1 0.0532 283 1923 exclusion phecode
276.41 Acidosis Endocrine/metabolic 0.859 0.75 – 0.985 0.0301 243 1699 exclusion phecode
276.42 Alkalosis Endocrine/metabolic 0.83 0.641 – 1.08 0.16 65 443 exclusion phecode
276.5 Hypovolemia Endocrine/metabolic 1.01 0.927 – 1.1 0.854 682 3509 exclusion phecode
276.6 Fluid overload Endocrine/metabolic 0.859 0.729 – 1.01 0.0695 162 1236 exclusion phecode
276.8 Polydipsia Endocrine/metabolic 0.941 0.617 – 1.44 0.779 28 158 exclusion phecode
277 Other disorders of metabolism Endocrine/metabolic 0.978 0.902 – 1.06 0.589 724 4055 exclusion phecode
277.2
Other disorders of purine and pyrimidine
Other disorders of purine and pyrimidine metabolism
 Endocrine/metabolic 1.2 0.898 – 1.59 0.221 52 470 exclusion phecode
277.4 Disorders of bilirubin excretion Endocrine/metabolic 0.966 0.795 – 1.17 0.731 113 701 exclusion phecode
277.5 Other disorders of lipoid metabolism Endocrine/metabolic 0.9 0.757 – 1.07 0.23 158 1161 exclusion phecode
277.51 Lipoprotein disorders Endocrine/metabolic 0.891 0.73 – 1.09 0.253 115 949 exclusion phecode
277.7 Dysmetabolic syndrome X Endocrine/metabolic 0.976 0.813 – 1.17 0.794 126 1203 exclusion phecode
278 Overweight, obesity and other hyperalimentation Endocrine/metabolic 1.09 1.03 – 1.15 0.00413 2053 3169 exclusion phecode
278.1 Obesity Endocrine/metabolic 1.11 1.04 – 1.18 0.00174 1508 3168 exclusion phecode
278.11 Morbid obesity Endocrine/metabolic 1.21 1.11 – 1.31 1.24e-05 704 3144 exclusion phecode
278.3 Localized adiposity Endocrine/metabolic 1.07 0.802 – 1.42 0.652 58 495 exclusion phecode
278.4 Abnormal weight gain Endocrine/metabolic 1.06 0.967 – 1.17 0.2 552 2521 exclusion phecode
279 Disorders involving the immune mechanism Endocrine/metabolic 0.929 0.846 – 1.02 0.121 550 3086 exclusion phecode
279.1 Immunity deficiency Endocrine/metabolic 0.904 0.774 – 1.05 0.199 199 1250 exclusion phecode
279.11 Deficiency of humoral immunity Endocrine/metabolic 0.801 0.614 – 1.04 0.1 67 397 exclusion phecode
279.2 Autoimmune disease NEC Endocrine/metabolic 0.953 0.809 – 1.12 0.563 183 1031 exclusion phecode
279.7 Other immunological findings Endocrine/metabolic 0.935 0.869 – 1.01 0.0718 976 3766 exclusion phecode
279.8
Other specified disorders involving the immune
Other specified disorders involving the immune mechanism
 Endocrine/metabolic 0.97 0.806 – 1.17 0.747 144 805 exclusion phecode
280 Iron deficiency anemias Hematopoietic 1.04 0.956 – 1.12 0.389 805 3065 exclusion phecode
280.1
Iron deficiency anemias, unspecified or not due
Iron deficiency anemias, unspecified or not due to blood loss
 Hematopoietic 1.03 0.952 – 1.12 0.444 779 3057 exclusion phecode
280.2
Iron deficiency anemia secondary to blood loss
Iron deficiency anemia secondary to blood loss (chronic)
 Hematopoietic 1.06 0.931 – 1.2 0.386 269 1724 exclusion phecode
281 Other deficiency anemia Hematopoietic 0.911 0.726 – 1.14 0.422 101 555 exclusion phecode
281.1 Megaloblastic anemia Hematopoietic 0.737 0.538 – 1.01 0.058 55 302 exclusion phecode
281.11 Pernicious anemia Hematopoietic 0.706 0.424 – 1.18 0.182 24 134 exclusion phecode
281.12 Other vitamin B12 deficiency anemia Hematopoietic 0.783 0.552 – 1.11 0.172 43 231 exclusion phecode
281.9 Deficiency anemias Hematopoietic 0.981 0.715 – 1.35 0.905 52 297 exclusion phecode
282 Hereditary hemolytic anemias Hematopoietic 0.684 0.502 – 0.931 0.0159 47 328 exclusion phecode
282.8 Other hemoglobinopathies Hematopoietic 0.79 0.536 – 1.17 0.235 30 229 exclusion phecode
282.9 Other hereditary hemolytic anemias Hematopoietic 0.584 0.378 – 0.903 0.0156 28 188 exclusion phecode
283 Acquired hemolytic anemias Hematopoietic 0.905 0.525 – 1.56 0.718 12 148 exclusion phecode
283.1 Autoimmune hemolytic anemias Hematopoietic 1.15 0.4 – 3.32 0.792 6 60 exclusion phecode
284 Aplastic anemia Hematopoietic 0.831 0.659 – 1.05 0.119 83 649 exclusion phecode
284.1 Pancytopenia Hematopoietic 0.797 0.613 – 1.04 0.0904 63 543 exclusion phecode
285 Other anemias Hematopoietic 0.991 0.933 – 1.05 0.76 1835 3213 exclusion phecode
285.1 Acute posthemorrhagic anemia Hematopoietic 0.937 0.841 – 1.04 0.235 408 2548 exclusion phecode
285.2 Anemia of chronic disease Hematopoietic 0.954 0.834 – 1.09 0.491 252 1856 exclusion phecode
285.21 Anemia in chronic kidney disease Hematopoietic 0.866 0.72 – 1.04 0.124 137 872 exclusion phecode
285.22 Anemia in neoplastic disease Hematopoietic 1.24 0.978 – 1.56 0.0757 76 670 exclusion phecode
286 Coagulation defects Hematopoietic 0.932 0.846 – 1.03 0.156 480 3692 exclusion phecode
286.1 Congenital coagulation defects Hematopoietic 1.11 0.768 – 1.6 0.58 34 282 exclusion phecode
286.11 Von willebrand's disease Hematopoietic 1.18 0.615 – 2.26 0.62 11 97 exclusion phecode
286.12
Congenital deficiency of other clotting factors
Congenital deficiency of other clotting factors (including factor VII)
 Hematopoietic 1.09 0.676 – 1.75 0.732 17 156 exclusion phecode
286.2
Encounter for long-term (current) use of
Encounter for long-term (current) use of anticoagulants
 Hematopoietic 0.984 0.882 – 1.1 0.774 394 2625 exclusion phecode
286.3
Coagulation defects complicating pregnancy or
Coagulation defects complicating pregnancy or postpartum
 Hematopoietic 0.857 0.533 – 1.38 0.526 23 131 exclusion phecode
286.4 Acquired coagulation factor deficiency Hematopoietic 0.546 0.341 – 0.873 0.0114 19 219 exclusion phecode
286.5
Hemorrhagic disorder due to intrinsic
Hemorrhagic disorder due to intrinsic circulating anticoagulants
 Hematopoietic 1.03 0.593 – 1.79 0.917 11 119 exclusion phecode
286.6 Defibrination syndrome Hematopoietic 0.907 0.808 – 1.02 0.099 317 2813 exclusion phecode
286.7 Other and unspecified coagulation defects Hematopoietic 0.925 0.83 – 1.03 0.158 374 3251 exclusion phecode
286.8 Hypercoagulable state Hematopoietic 0.959 0.788 – 1.17 0.678 109 1026 exclusion phecode
286.81 Primary hypercoagulable state Hematopoietic 0.955 0.784 – 1.16 0.646 105 979 exclusion phecode
286.9 Abnormal coagulation profile Hematopoietic 1.03 0.861 – 1.23 0.757 136 1199 exclusion phecode
287 Purpura and other hemorrhagic conditions Hematopoietic 0.894 0.806 – 0.992 0.0347 420 2970 exclusion phecode
287.1 Spontaneous ecchymoses Hematopoietic 1.43 1.04 – 1.97 0.0297 55 240 exclusion phecode
287.3 Thrombocytopenia Hematopoietic 0.918 0.821 – 1.03 0.13 365 2645 exclusion phecode
287.31 Primary thrombocytopenia Hematopoietic 0.805 0.626 – 1.04 0.091 67 615 exclusion phecode
287.32 Secondary thrombocytopenia Hematopoietic 0.942 0.722 – 1.23 0.661 62 541 exclusion phecode
287.4 Qualitative platelet defects Hematopoietic 1.09 0.605 – 1.96 0.779 12 139 exclusion phecode
288 Diseases of white blood cells Hematopoietic 1.02 0.944 – 1.11 0.559 724 3705 exclusion phecode
288.1 Decreased white blood cell count Hematopoietic 1.08 0.949 – 1.23 0.244 294 1739 exclusion phecode
288.11 Neutropenia Hematopoietic 0.962 0.81 – 1.14 0.655 160 1173 exclusion phecode
288.2 Elevated white blood cell count Hematopoietic 1.01 0.922 – 1.1 0.857 599 3578 exclusion phecode
288.3 Eosinophilia Hematopoietic 1.3 0.864 – 1.97 0.206 33 202 exclusion phecode
289 Other diseases of blood and blood-forming organs Hematopoietic 1.07 0.952 – 1.2 0.26 348 2027 exclusion phecode
289.3
Personal history of diseases of blood and
Personal history of diseases of blood and blood-forming organs
 Hematopoietic 1.11 0.956 – 1.29 0.17 197 1176 exclusion phecode
289.4 Lymphadenitis Hematopoietic 0.976 0.893 – 1.07 0.588 602 3530 exclusion phecode
289.5 Diseases of spleen Hematopoietic 1.2 0.884 – 1.63 0.242 51 365 exclusion phecode
289.8 Polycythemia, secondary Hematopoietic 1.03 0.7 – 1.53 0.865 29 195 exclusion phecode
289.9 Abnormality of red blood cells Hematopoietic 0.923 0.726 – 1.17 0.515 78 439 exclusion phecode
290
Delirium dementia and amnestic and other
Delirium dementia and amnestic and other cognitive disorders
 Mental Disorders 1.03 0.878 – 1.2 0.737 202 1066 exclusion phecode
290.1 Dementias Mental Disorders 1.15 0.916 – 1.45 0.226 99 430 exclusion phecode
290.11 Alzheimer's disease Mental Disorders 1.02 0.681 – 1.53 0.925 34 147 exclusion phecode
290.12 Dementia with cerebral degenerations Mental Disorders 1.57 0.893 – 2.75 0.117 15 79 exclusion phecode
290.13 Senile dementia Mental Disorders 1.04 0.798 – 1.37 0.754 68 271 exclusion phecode
290.16 Vascular dementia Mental Disorders 1.01 0.459 – 2.23 0.977 14 66 exclusion phecode
290.2 Delirium due to conditions classified elsewhere Mental Disorders 0.914 0.738 – 1.13 0.408 99 637 exclusion phecode
290.3
Other persistent mental disorders due to
Other persistent mental disorders due to conditions classified elsewhere
 Mental Disorders 1.1 0.928 – 1.31 0.269 162 870 exclusion phecode
291
Other specified nonpsychotic and/or transient
Other specified nonpsychotic and/or transient mental disorders
 Mental Disorders 0.954 0.859 – 1.06 0.383 436 2666 exclusion phecode
291.1
Transient mental disorders due to conditions
Transient mental disorders due to conditions classified elsewhere
 Mental Disorders 0.927 0.657 – 1.31 0.664 40 251 exclusion phecode
291.4
Specific nonpsychotic mental disorders due to
Specific nonpsychotic mental disorders due to brain damage
 Mental Disorders 1.02 0.81 – 1.3 0.838 82 537 exclusion phecode
291.8 Alteration of consciousness Mental Disorders 0.962 0.854 – 1.08 0.527 340 2112 exclusion phecode
292 Neurological disorders Mental Disorders 1 0.93 – 1.08 0.93 884 3965 exclusion phecode
292.1 Aphasia/speech disturbance Mental Disorders 0.946 0.829 – 1.08 0.415 254 1927 exclusion phecode
292.11 Aphasia Mental Disorders 0.959 0.777 – 1.19 0.701 94 648 exclusion phecode
292.12 Symbolic dysfunction Mental Disorders 0.862 0.56 – 1.32 0.497 24 165 exclusion phecode
292.2 Mild cognitive impairment Mental Disorders 1.11 0.863 – 1.43 0.42 78 362 exclusion phecode
292.3 Memory loss Mental Disorders 1.06 0.949 – 1.19 0.298 396 1993 exclusion phecode
292.4 Altered mental status Mental Disorders 0.918 0.816 – 1.03 0.15 336 2227 exclusion phecode
292.5 Transient alteration of awareness Mental Disorders 0.981 0.764 – 1.26 0.881 76 461 exclusion phecode
292.6 Hallucinations Mental Disorders 0.936 0.657 – 1.33 0.714 38 227 exclusion phecode
293 Symptoms involving head and neck Mental Disorders 0.979 0.783 – 1.23 0.856 100 512 exclusion phecode
293.1
Swelling, mass, or lump in head and neck
Swelling, mass, or lump in head and neck [Space-occupying lesion, intracranial NOS]
 Mental Disorders 0.89 0.815 – 0.97 0.00837 618 4208 exclusion phecode
295 Schizophrenia and other psychotic disorders Mental Disorders 0.971 0.811 – 1.16 0.75 171 602 exclusion phecode
295.1 Schizophrenia Mental Disorders 1.02 0.642 – 1.64 0.92 23 97 exclusion phecode
295.2 Paranoid disorders Mental Disorders 1.38 0.749 – 2.54 0.301 18 70 exclusion phecode
295.3 Psychosis Mental Disorders 0.919 0.758 – 1.11 0.387 153 490 exclusion phecode
296 Mood disorders Mental Disorders 1.06 0.985 – 1.13 0.126 2307 1405 exclusion phecode
296.1 Bipolar Mental Disorders 0.999 0.855 – 1.17 0.985 222 891 exclusion phecode
296.2 Depression Mental Disorders 1.06 0.985 – 1.13 0.124 2240 1401 exclusion phecode
296.22 Major depressive disorder Mental Disorders 1.06 0.988 – 1.14 0.106 2061 1403 exclusion phecode
297 Suicidal ideation or attempt Mental Disorders 1.05 0.877 – 1.27 0.576 155 649 exclusion phecode
297.1 Suicidal ideation Mental Disorders 1.03 0.833 – 1.27 0.805 116 538 exclusion phecode
297.2 Suicide or self-inflicted injury Mental Disorders 1.07 0.777 – 1.47 0.687 59 190 exclusion phecode
300 Anxiety disorders Mental Disorders 1.06 0.986 – 1.13 0.12 2425 1402 exclusion phecode
300.1 Anxiety disorder Mental Disorders 1.06 0.987 – 1.14 0.11 2264 1403 exclusion phecode
300.11 Generalized anxiety disorder Mental Disorders 1.04 0.953 – 1.13 0.39 1052 1391 exclusion phecode
300.12 Agorophobia, social phobia, and panic disorder Mental Disorders 1.15 0.991 – 1.32 0.0654 272 925 exclusion phecode
300.13 Phobia Mental Disorders 0.99 0.842 – 1.16 0.904 206 789 exclusion phecode
300.3 Obsessive-compulsive disorders Mental Disorders 1.12 0.857 – 1.45 0.416 74 268 exclusion phecode
300.4 Dysthymic disorder Mental Disorders 1.04 0.935 – 1.15 0.478 532 1264 exclusion phecode
300.8 Acute reaction to stress Mental Disorders 1.03 0.833 – 1.27 0.8 139 475 exclusion phecode
300.9 Posttraumatic stress disorder Mental Disorders 0.964 0.78 – 1.19 0.733 117 596 exclusion phecode
301 Personality disorders Mental Disorders 1.12 0.869 – 1.43 0.391 88 387 exclusion phecode
301.2 Antisocial/borderline personality disorder Mental Disorders 1.12 0.79 – 1.58 0.528 43 193 exclusion phecode
302 Sexual and gender identity disorders Mental Disorders 1.09 0.954 – 1.24 0.207 371 769 exclusion phecode
302.1 Decreased libido Mental Disorders 0.936 0.739 – 1.19 0.588 94 372 exclusion phecode
303 Psychogenic and somatoform disorders Mental Disorders 0.986 0.913 – 1.06 0.716 1558 1380 exclusion phecode
303.1 Dissociative disorder Mental Disorders 1.08 0.706 – 1.65 0.725 26 132 exclusion phecode
303.3 Psychogenic disorder Mental Disorders 0.992 0.918 – 1.07 0.841 1513 1371 exclusion phecode
303.31
Gastrointestinal malfunction arising from
Gastrointestinal malfunction arising from mental factors
 Mental Disorders 1.12 0.898 – 1.4 0.314 107 415 exclusion phecode
303.4 Somatoform disorder Mental Disorders 0.91 0.774 – 1.07 0.254 197 896 exclusion phecode
304 Adjustment reaction Mental Disorders 1 0.916 – 1.1 0.924 784 1393 exclusion phecode
305.2 Eating disorder Mental Disorders 1.09 0.927 – 1.27 0.304 185 769 exclusion phecode
306 Other mental disorder Mental Disorders 1.02 0.907 – 1.16 0.697 386 1145 exclusion phecode
306.1 Mental disorders durring/after pregnancy Mental Disorders 1.05 0.841 – 1.31 0.673 129 358 exclusion phecode
306.9 Tension headache Mental Disorders 1.06 0.89 – 1.27 0.498 168 684 exclusion phecode
312 Conduct disorders Mental Disorders 1.23 0.859 – 1.77 0.257 48 220 exclusion phecode
312.3 Impulse control disorder Mental Disorders 0.909 0.496 – 1.67 0.758 18 89 exclusion phecode
313 Pervasive developmental disorders Mental Disorders 0.982 0.848 – 1.14 0.813 216 1500 exclusion phecode
313.1 Attention deficit hyperactivity disorder Mental Disorders 0.981 0.837 – 1.15 0.814 185 1339 exclusion phecode
313.2 Tics and stuttering Mental Disorders 1.03 0.536 – 2 0.92 12 53 exclusion phecode
313.3 Autism Mental Disorders 0.998 0.39 – 2.55 0.997 9 41 exclusion phecode
315 Develomental delays and disorders Mental Disorders 1.01 0.813 – 1.24 0.962 101 695 exclusion phecode
315.1 Learning disorder Mental Disorders 0.967 0.445 – 2.1 0.933 10 77 exclusion phecode
315.2 Speech and language disorder Mental Disorders 0.888 0.625 – 1.26 0.509 43 260 exclusion phecode
316 Substance addiction and disorders Mental Disorders 1.01 0.923 – 1.11 0.784 525 3415 exclusion phecode
316.1 Polyneuropathy due to drugs Mental Disorders 1.19 0.966 – 1.47 0.103 103 775 exclusion phecode
317 Alcohol-related disorders Mental Disorders 0.919 0.823 – 1.03 0.131 402 1901 exclusion phecode
317.1 Alcoholism Mental Disorders 0.937 0.831 – 1.06 0.284 336 1560 exclusion phecode
317.11 Alcoholic liver damage Mental Disorders 0.967 0.712 – 1.31 0.828 48 335 exclusion phecode
318 Tobacco use disorder Mental Disorders 0.94 0.873 – 1.01 0.107 919 3728 exclusion phecode
320 Meningitis Neurological 0.888 0.664 – 1.19 0.427 48 424 exclusion phecode
323 Encephalitis Neurological 1.07 0.725 – 1.57 0.74 29 189 exclusion phecode
323.8 Encephalitis, non-infectious Neurological 1.24 0.818 – 1.89 0.307 26 156 exclusion phecode
324 Other CNS infection and poliomyelitis Neurological 1.18 0.823 – 1.69 0.369 32 279 exclusion phecode
325
Phlebitis and thrombophlebitis of intracranial
Phlebitis and thrombophlebitis of intracranial venous sinuses
 Neurological 1.47 0.587 – 3.69 0.41 6 65 exclusion phecode
327 Sleep disorders Neurological 1.04 0.977 – 1.1 0.241 2136 3079 exclusion phecode
327.1 Hypersomnia Neurological 1.1 0.977 – 1.23 0.12 375 2090 exclusion phecode
327.3 Sleep apnea Neurological 1.08 1.01 – 1.16 0.0298 1186 3041 exclusion phecode
327.31 Central/nonobstroctive sleep apnea Neurological 0.873 0.682 – 1.12 0.282 78 477 exclusion phecode
327.32 Obstructive sleep apnea Neurological 1.1 1.02 – 1.19 0.0103 1028 2989 exclusion phecode
327.4 Insomnia Neurological 1.04 0.973 – 1.12 0.228 1195 3049 exclusion phecode
327.41 Organic or persistent insomnia Neurological 1 0.885 – 1.13 0.979 343 1397 exclusion phecode
327.5 Parasomnia Neurological 1.05 0.834 – 1.33 0.659 92 561 exclusion phecode
327.6 Circadian rhythm sleep disorder Neurological 1.12 0.83 – 1.51 0.458 57 328 exclusion phecode
327.7 Sleep related movement disorders Neurological 1.09 0.966 – 1.23 0.161 323 1963 exclusion phecode
327.71 Restless legs syndrome Neurological 1.05 0.926 – 1.2 0.423 275 1777 exclusion phecode
327.72 Sleep related leg cramps Neurological 1.57 0.887 – 2.77 0.121 27 96 exclusion phecode
331 Other cerebral degenerations Neurological 1 0.816 – 1.24 0.965 102 697 exclusion phecode
331.1 Hydrocephalus Neurological 1.31 0.838 – 2.04 0.237 22 272 exclusion phecode
331.9 Cerebral degeneration, unspecified Neurological 0.967 0.74 – 1.26 0.804 74 407 exclusion phecode
332 Parkinson's disease Neurological 1.1 0.825 – 1.46 0.526 57 343 exclusion phecode
333
Extrapyramidal disease and abnormal movement
Extrapyramidal disease and abnormal movement disorders
 Neurological 1.08 0.982 – 1.19 0.112 516 3047 exclusion phecode
333.1 Essential tremor Neurological 1.02 0.855 – 1.22 0.806 141 765 exclusion phecode
333.2 Myoclonus Neurological 1.41 0.939 – 2.12 0.0977 31 182 exclusion phecode
333.4 Torsion dystonia Neurological 0.974 0.756 – 1.25 0.836 67 398 exclusion phecode
333.8 Other degenerative diseases of the basal ganglia Neurological 1.27 0.765 – 2.12 0.353 18 77 exclusion phecode
334 Degenerative disease of the spinal cord Neurological 1.03 0.858 – 1.24 0.746 120 1073 exclusion phecode
334.1 Spinocerebellar disease Neurological 1.62 0.656 – 4.01 0.295 5 77 exclusion phecode
334.2 Anterior horn cell disease Neurological 0.586 0.309 – 1.11 0.103 15 98 exclusion phecode
334.21 Amyotrophic Lateral Sclerosis Neurological 0.939 0.388 – 2.27 0.889 8 66 exclusion phecode
335 Multiple sclerosis Neurological 1.06 0.814 – 1.39 0.646 64 495 exclusion phecode
337 Disorders of the autonomic nervous system Neurological 0.883 0.729 – 1.07 0.202 127 859 exclusion phecode
337.1 Peripheral autonomic neuropathy Neurological 0.788 0.608 – 1.02 0.0726 72 449 exclusion phecode
338 Pain Neurological 1.02 0.965 – 1.08 0.466 2864 2361 exclusion phecode
338.1 Acute pain Neurological 1.01 0.947 – 1.07 0.803 2040 2344 exclusion phecode
338.2 Chronic pain Neurological 1.03 0.968 – 1.1 0.345 1906 2345 exclusion phecode
339 Other headache syndromes Neurological 1.01 0.952 – 1.08 0.675 1663 3170 exclusion phecode
340 Migraine Neurological 1.03 0.962 – 1.1 0.393 1241 2958 exclusion phecode
340.1 Migrain with aura Neurological 0.982 0.903 – 1.07 0.671 771 2605 exclusion phecode
341
Other demyelinating diseases of central nervous
Other demyelinating diseases of central nervous system
 Neurological 0.895 0.6 – 1.34 0.588 27 158 exclusion phecode
342 Hemiplegia Neurological 0.949 0.72 – 1.25 0.711 54 467 exclusion phecode
343 Infantile cerebral palsy Neurological 1.81 0.95 – 3.44 0.0714 10 81 exclusion phecode
344 Other paralytic syndromes Neurological 0.991 0.798 – 1.23 0.933 93 678 exclusion phecode
345 Epilepsy, recurrent seizures, convulsions Neurological 0.978 0.869 – 1.1 0.708 314 2642 exclusion phecode
345.1 Epilepsy Neurological 0.972 0.787 – 1.2 0.789 104 763 exclusion phecode
345.11 Generalized convulsive epilepsy Neurological 0.959 0.63 – 1.46 0.845 27 208 exclusion phecode
345.12 Partial epilepsy Neurological 1.04 0.808 – 1.35 0.747 76 553 exclusion phecode
345.3 Convulsions Neurological 0.972 0.861 – 1.1 0.646 298 2468 exclusion phecode
346
Abnormal findings on study of brain and/or
Abnormal findings on study of brain and/or nervous system
 Neurological 0.673 0.458 – 0.989 0.0437 29 188 exclusion phecode
346.1
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of skull and head
 Neurological 1.01 0.887 – 1.15 0.86 268 1568 exclusion phecode
346.2
Nonspecific abnormal results of function study
Nonspecific abnormal results of function study of brain and central nervous system
 Neurological 0.828 0.518 – 1.32 0.43 17 113 exclusion phecode
346.3
Nonspecific abnormal findings in cerebrospinal
Nonspecific abnormal findings in cerebrospinal fluid
 Neurological 0.794 0.461 – 1.37 0.406 13 118 exclusion phecode
347 Cataplexy and narcolepsy Neurological 0.761 0.403 – 1.44 0.402 13 127 exclusion phecode
348 Other conditions of brain Neurological 1.11 0.959 – 1.29 0.157 201 1827 exclusion phecode
348.2 Cerebral edema and compression of brain Neurological 1.01 0.777 – 1.3 0.963 68 851 exclusion phecode
348.4 Cerebral cysts Neurological 1.34 0.945 – 1.89 0.101 35 226 exclusion phecode
348.7 Coma Neurological 0.817 0.587 – 1.14 0.232 38 231 exclusion phecode
348.8 Encephalopathy, not elsewhere classified Neurological 1.1 0.909 – 1.34 0.318 113 872 exclusion phecode
348.9 Other conditions of brain, NOS Neurological 0.973 0.857 – 1.11 0.675 271 2366 exclusion phecode
349
Other and unspecified disorders of the nervous
Other and unspecified disorders of the nervous system
 Neurological 1.01 0.842 – 1.2 0.94 133 982 exclusion phecode
350 Abnormal movement Neurological 1.03 0.957 – 1.1 0.468 1142 3891 exclusion phecode
350.1 Abnormal involuntary movements Neurological 1.08 0.982 – 1.18 0.114 576 3231 exclusion phecode
350.2 Abnormality of gait Neurological 1.01 0.925 – 1.1 0.834 682 3075 exclusion phecode
350.3 Lack of coordination Neurological 0.967 0.827 – 1.13 0.669 187 1138 exclusion phecode
350.5 Abnormal reflex Neurological 0.943 0.678 – 1.31 0.729 42 244 exclusion phecode
350.6 Disturbances of sensation of smell and taste Neurological 1.22 0.958 – 1.55 0.107 82 548 exclusion phecode
351 Other peripheral nerve disorders Neurological 1.01 0.942 – 1.08 0.849 1354 3281 exclusion phecode
352 Disorders of other cranial nerves Neurological 0.873 0.747 – 1.02 0.0874 180 1642 exclusion phecode
352.1 Trigeminal nerve disorders [CN5] Neurological 0.831 0.663 – 1.04 0.109 90 589 exclusion phecode
352.2 Facial nerve disorders [CN7] Neurological 0.99 0.784 – 1.25 0.933 72 789 exclusion phecode
353 Nerve root and plexus disorders Neurological 0.996 0.918 – 1.08 0.924 744 3138 exclusion phecode
353.1 Nerve plexus lesions Neurological 1.07 0.771 – 1.49 0.679 46 348 exclusion phecode
353.2 Nerve root lesions Neurological 0.964 0.579 – 1.6 0.887 20 122 exclusion phecode
355 Complex regional/central pain syndrome Neurological 0.96 0.768 – 1.2 0.718 81 541 exclusion phecode
355.1 Chronic pain syndrome Neurological 1.21 0.998 – 1.46 0.0524 132 882 exclusion phecode
356 Hereditary and idiopathic peripheral neuropathy Neurological 1.01 0.904 – 1.13 0.837 368 2282 exclusion phecode
357 Inflammatory and toxic neuropathy Neurological 0.99 0.897 – 1.09 0.84 491 3260 exclusion phecode
358 Myoneural disorders Neurological 0.958 0.83 – 1.11 0.562 209 1420 exclusion phecode
358.1 Myasthenia gravis Neurological 1.22 0.709 – 2.09 0.477 15 110 exclusion phecode
359 Muscular dystrophies and other myopathies Neurological 1.14 0.991 – 1.32 0.0671 248 1386 exclusion phecode
359.1 Muscular dystrophies Neurological 1.46 0.672 – 3.19 0.338 7 65 exclusion phecode
359.2 Myopathy Neurological 1.14 0.987 – 1.32 0.0736 243 1311 exclusion phecode
360 Disorders of the globe Sense Organs 0.686 0.436 – 1.08 0.104 29 128 exclusion phecode
360.2 Progressive myopia Sense Organs 0.564 0.318 – 1 0.0502 17 75 exclusion phecode
361 Retinal detachments and defects Sense Organs 0.814 0.683 – 0.97 0.0214 166 730 exclusion phecode
361.1 Retinal detachment with retinal defect Sense Organs 0.667 0.503 – 0.886 0.00514 72 304 exclusion phecode
362 Other retinal disorders Sense Organs 0.883 0.81 – 0.963 0.00481 800 2283 exclusion phecode
362.2
Degeneration of macula and posterior pole of
Degeneration of macula and posterior pole of retina
 Sense Organs 0.877 0.789 – 0.975 0.0147 515 1587 exclusion phecode
362.21 Macular degeneration, dry Sense Organs 0.778 0.61 – 0.991 0.0423 103 298 exclusion phecode
362.22 Macular degeneration, wet Sense Organs 0.645 0.39 – 1.07 0.0867 27 106 exclusion phecode
362.23 Cystoid macular degeneration of retina Sense Organs 0.867 0.703 – 1.07 0.181 100 384 exclusion phecode
362.26 Macular puckering of retina Sense Organs 0.857 0.741 – 0.991 0.0372 238 916 exclusion phecode
362.27 Drusen (degenerative) of retina Sense Organs 0.875 0.721 – 1.06 0.177 158 516 exclusion phecode
362.29 Macular degeneration (senile) of retina NOS Sense Organs 0.865 0.774 – 0.966 0.0102 457 1483 exclusion phecode
362.3 Other nondiabetic retinopathy Sense Organs 0.901 0.765 – 1.06 0.212 188 880 exclusion phecode
362.31 Separation of retinal layers Sense Organs 0.773 0.604 – 0.989 0.0404 86 388 exclusion phecode
362.4 Retinal vascular changes and abnomalities Sense Organs 0.842 0.685 – 1.04 0.104 131 552 exclusion phecode
362.6 Peripheral retinal degenerations Sense Organs 0.635 0.503 – 0.801 0.000131 106 431 exclusion phecode
362.7 Hereditary retinal dystrophies Sense Organs 1.02 0.762 – 1.35 0.914 52 245 exclusion phecode
362.8 Retinal hemorrhage/ischemia Sense Organs 0.859 0.641 – 1.15 0.308 59 249 exclusion phecode
362.9 Retinal edema Sense Organs 0.881 0.658 – 1.18 0.393 54 347 exclusion phecode
363
Chorioretinal inflammations, scars, and other
Chorioretinal inflammations, scars, and other disorders of choroid
 Sense Organs 0.858 0.696 – 1.06 0.153 107 474 exclusion phecode
363.3 Chorioretinal scars Sense Organs 1.01 0.78 – 1.31 0.936 73 299 exclusion phecode
364 Corneal opacity and other disorders of cornea Sense Organs 0.93 0.809 – 1.07 0.306 251 1172 exclusion phecode
364.1 Corneal opacity Sense Organs 0.991 0.789 – 1.25 0.938 86 434 exclusion phecode
364.2 Corneal edema Sense Organs 0.649 0.374 – 1.13 0.125 20 102 exclusion phecode
364.4 Corneal degenerations Sense Organs 0.922 0.731 – 1.16 0.49 93 469 exclusion phecode
364.41 Keratoconus Sense Organs 0.661 0.33 – 1.33 0.244 11 99 exclusion phecode
364.5 Corneal dystrophy Sense Organs 1.01 0.823 – 1.23 0.956 118 515 exclusion phecode
364.51 Fuchs' dystrophy Sense Organs 0.905 0.689 – 1.19 0.473 62 282 exclusion phecode
364.9 Cornea replaced by transplant Sense Organs 0.82 0.405 – 1.66 0.581 12 80 exclusion phecode
365 Glaucoma Sense Organs 0.97 0.88 – 1.07 0.534 548 2279 exclusion phecode
365.1 Open-angle glaucoma Sense Organs 0.919 0.781 – 1.08 0.307 181 673 exclusion phecode
365.11 Primary open angle glaucoma Sense Organs 0.872 0.7 – 1.09 0.223 96 376 exclusion phecode
365.2 Primary angle-closure glaucoma Sense Organs 0.934 0.699 – 1.25 0.643 64 278 exclusion phecode
366 Cataract Sense Organs 0.995 0.927 – 1.07 0.88 1787 2678 exclusion phecode
366.1 Nonsenile Cataract Sense Organs 1.17 0.845 – 1.63 0.341 53 180 exclusion phecode
366.2 Senile cataract Sense Organs 1.01 0.932 – 1.09 0.848 1308 2397 exclusion phecode
367
Disorders of refraction and accommodation
Disorders of refraction and accommodation; blindness and low vision
 Sense Organs 0.987 0.932 – 1.04 0.646 2143 3089 exclusion phecode
367.1 Myopia Sense Organs 0.967 0.905 – 1.03 0.328 1318 2991 exclusion phecode
367.2 Astigmatism Sense Organs 0.992 0.924 – 1.07 0.834 1090 2899 exclusion phecode
367.8 Hypermetropia Sense Organs 1.01 0.913 – 1.11 0.893 571 1870 exclusion phecode
367.9 Blindness and low vision Sense Organs 1.08 0.94 – 1.25 0.266 237 1091 exclusion phecode
368 Visual disturbances Sense Organs 1.03 0.964 – 1.1 0.36 1179 3942 exclusion phecode
368.1 Amblyopia Sense Organs 1.21 0.993 – 1.47 0.0582 131 728 exclusion phecode
368.2 Diplopia and disorders of binocular vision Sense Organs 1.02 0.875 – 1.19 0.793 196 1121 exclusion phecode
368.3 Anisometropia Sense Organs 1.13 0.832 – 1.53 0.435 59 231 exclusion phecode
368.4 Visual field defects Sense Organs 0.98 0.846 – 1.14 0.791 206 1242 exclusion phecode
368.9 Subjective visual disturbances Sense Organs 1.01 0.881 – 1.16 0.86 254 1203 exclusion phecode
368.91 Psychophysical visual disturbances Sense Organs 1 0.612 – 1.65 0.989 18 115 exclusion phecode
369 Infection of the eye Sense Organs 0.943 0.871 – 1.02 0.151 801 2837 exclusion phecode
369.2 Eye infection, viral Sense Organs 0.896 0.728 – 1.1 0.304 120 550 exclusion phecode
369.5 Conjunctivitis, infectious Sense Organs 0.962 0.884 – 1.05 0.366 697 2628 exclusion phecode
370 Keratitis Sense Organs 0.928 0.821 – 1.05 0.235 339 1430 exclusion phecode
370.1 Corneal ulcer Sense Organs 0.743 0.546 – 1.01 0.0587 58 271 exclusion phecode
370.2 Superficial keratitis Sense Organs 1.09 0.896 – 1.31 0.403 149 592 exclusion phecode
370.3 Keratoconjunctivitis Sense Organs 0.814 0.676 – 0.981 0.0305 150 718 exclusion phecode
370.31 Keratoconjunctivitis sicca Sense Organs 0.823 0.585 – 1.16 0.265 55 239 exclusion phecode
371 Inflammation of the eye Sense Organs 0.954 0.887 – 1.02 0.195 1121 3056 exclusion phecode
371.1 Uveitis, noninfectious or NOS Sense Organs 1.11 0.902 – 1.37 0.323 119 601 exclusion phecode
371.2 Conjunctivitis, noninfectious Sense Organs 0.925 0.804 – 1.06 0.272 268 1060 exclusion phecode
371.21 Allergic conjunctivitis Sense Organs 0.871 0.749 – 1.01 0.0729 228 897 exclusion phecode
371.3 Inflammation of eyelids Sense Organs 0.95 0.876 – 1.03 0.207 882 2644 exclusion phecode
371.33 Noninfectious dermatoses of eyelid Sense Organs 0.859 0.606 – 1.22 0.396 49 183 exclusion phecode
372 Disorders of conjunctiva Sense Organs 1.01 0.885 – 1.15 0.895 294 1082 exclusion phecode
374 Other disorders of eyelids Sense Organs 0.975 0.891 – 1.07 0.576 669 2375 exclusion phecode
374.1 Ectropion or entropion Sense Organs 1.09 0.84 – 1.42 0.507 73 328 exclusion phecode
374.2 Lagophthalmos Sense Organs 0.545 0.336 – 0.884 0.0138 26 184 exclusion phecode
374.3 Ptosis of eyelid Sense Organs 0.962 0.836 – 1.11 0.594 256 1110 exclusion phecode
374.6 Dermatochalasis Sense Organs 1.01 0.881 – 1.16 0.879 274 1067 exclusion phecode
375 Disorders of lacrimal system Sense Organs 0.963 0.89 – 1.04 0.351 985 2628 exclusion phecode
375.1 Dry eyes Sense Organs 0.977 0.906 – 1.05 0.548 1112 2692 exclusion phecode
375.2 Epiphora Sense Organs 0.784 0.618 – 0.996 0.046 88 437 exclusion phecode
376 Disorders of the orbit Sense Organs 1.08 0.787 – 1.48 0.64 51 297 exclusion phecode
377 Disorders of optic nerve and visual pathways Sense Organs 0.992 0.828 – 1.19 0.934 142 873 exclusion phecode
377.1 Optic atrophy Sense Organs 0.984 0.738 – 1.31 0.912 62 270 exclusion phecode
377.3 Optic neuritis/neuropathy Sense Organs 0.922 0.719 – 1.18 0.519 77 538 exclusion phecode
378
Strabismus and other disorders of binocular eye
Strabismus and other disorders of binocular eye movements
 Sense Organs 1.11 0.953 – 1.3 0.176 196 1113 exclusion phecode
378.1 Strabismus (not specified as paralytic) Sense Organs 1.13 0.936 – 1.36 0.204 136 735 exclusion phecode
378.2 Nystagmus and other irregular eye movements Sense Organs 0.752 0.471 – 1.2 0.233 24 155 exclusion phecode
378.5 Paralytic strabismus Sense Organs 1.23 0.86 – 1.77 0.253 37 291 exclusion phecode
379 Other disorders of eye Sense Organs 0.979 0.911 – 1.05 0.563 1240 2801 exclusion phecode
379.1 Scleritis and episcleritis Sense Organs 1.07 0.749 – 1.54 0.697 37 218 exclusion phecode
379.2 Disorders of vitreous body Sense Organs 0.99 0.913 – 1.07 0.804 969 2240 exclusion phecode
379.3 Aphakia and other disorders of lens Sense Organs 1.04 0.694 – 1.55 0.856 32 115 exclusion phecode
379.4 Anomalies of pupillary function Sense Organs 1.46 1.07 – 1.98 0.0154 47 280 exclusion phecode
379.5 Disorders of iris and ciliary body Sense Organs 1.12 0.83 – 1.51 0.463 62 279 exclusion phecode
379.51 Pigmentary iris degeneration Sense Organs 1.68 0.954 – 2.96 0.0722 23 58 exclusion phecode
379.9 Pain, swelling or discharge of eye Sense Organs 1.03 0.902 – 1.18 0.632 253 1171 exclusion phecode
380 Disorders of external ear Sense Organs 1.04 0.941 – 1.14 0.453 540 2190 exclusion phecode
380.1 Otitis externa Sense Organs 1.04 0.909 – 1.18 0.585 278 1703 exclusion phecode
380.4 Impacted cerumen Sense Organs 1.09 0.999 – 1.19 0.0532 670 2538 exclusion phecode
381 Otitis media and Eustachian tube disorders Sense Organs 1.04 0.962 – 1.12 0.337 834 3853 exclusion phecode
381.1 Otitis media Sense Organs 1.04 0.948 – 1.14 0.401 523 3194 exclusion phecode
381.11 Suppurative and unspecified otitis media Sense Organs 1.02 0.917 – 1.13 0.753 437 2771 exclusion phecode
381.2 Eustachian tube disorders Sense Organs 1.05 0.95 – 1.16 0.332 473 2202 exclusion phecode
381.3 Mastoiditis & related conditions Sense Organs 1.04 0.623 – 1.74 0.882 11 145 exclusion phecode
381.9 Otorrhea Sense Organs 1.38 1 – 1.89 0.0494 48 359 exclusion phecode
382 Otalgia Sense Organs 1.03 0.931 – 1.15 0.53 423 2371 exclusion phecode
383 Otosclerosis Sense Organs 0.875 0.519 – 1.47 0.615 19 126 exclusion phecode
384 Other disorders of tympanic membrane Sense Organs 0.959 0.746 – 1.23 0.744 80 508 exclusion phecode
384.1 Myringitis Sense Organs 1.33 0.638 – 2.77 0.446 10 49 exclusion phecode
384.4 Perforation of tympanic membrane Sense Organs 0.948 0.719 – 1.25 0.707 66 400 exclusion phecode
385 Other disorders of middle ear and mastoid Sense Organs 1.2 0.861 – 1.67 0.282 46 382 exclusion phecode
385.3 Cholesteatoma Sense Organs 0.921 0.561 – 1.51 0.743 18 202 exclusion phecode
385.5
Tympanosclerosis and middle ear disease related
Tympanosclerosis and middle ear disease related to otitis media
 Sense Organs 1.26 0.693 – 2.3 0.445 11 97 exclusion phecode
386
Vertiginous syndromes and other disorders of
Vertiginous syndromes and other disorders of vestibular system
 Sense Organs 1.12 1.01 – 1.26 0.0381 387 2108 exclusion phecode
386.1 Meniere's disease Sense Organs 1.21 0.857 – 1.71 0.277 40 370 exclusion phecode
386.2 Peripheral or central vertigo Sense Organs 1.12 0.997 – 1.26 0.0565 338 1843 exclusion phecode
386.21 Central origin vertigo Sense Organs 1.02 0.887 – 1.17 0.802 255 1446 exclusion phecode
386.3 Labyrinthitis Sense Organs 1.05 0.92 – 1.19 0.495 300 1707 exclusion phecode
386.9
Dizziness and giddiness (Light-headedness and
Dizziness and giddiness (Light-headedness and vertigo)
 Sense Organs 1.07 1 – 1.14 0.0433 1377 3749 exclusion phecode
388 Other disorders of ear Sense Organs 1.02 0.87 – 1.19 0.815 195 1103 exclusion phecode
389 Hearing loss Sense Organs 1 0.941 – 1.07 0.89 1407 3687 exclusion phecode
389.1 Sensorineural hearing loss Sense Organs 1.02 0.94 – 1.11 0.64 842 2888 exclusion phecode
389.2 Conductive hearing loss Sense Organs 1.09 0.909 – 1.31 0.344 135 855 exclusion phecode
389.3 Degenerative and vascular disorders of ear Sense Organs 1.21 0.856 – 1.7 0.284 58 189 exclusion phecode
389.4 Tinnitus Sense Organs 0.967 0.873 – 1.07 0.529 461 2272 exclusion phecode
389.5 Disorders of acoustic nerve Sense Organs 0.852 0.575 – 1.26 0.426 32 150 exclusion phecode
394 Rheumatic disease of the heart valves Circulatory System 0.784 0.683 – 0.9 0.000554 268 1324 exclusion phecode
394.1 Mitral valve stenosis and aortic valve stenosis Circulatory System 0.767 0.578 – 1.02 0.0657 65 280 exclusion phecode
394.2 Mitral valve disease Circulatory System 0.71 0.557 – 0.904 0.00541 87 501 exclusion phecode
394.3 Aortic valve disease Circulatory System 0.752 0.506 – 1.12 0.16 38 103 exclusion phecode
394.4 Acute rheumatic heart disease Circulatory System 0.494 0.236 – 1.04 0.0625 12 65 exclusion phecode
394.7 Disease of tricuspid valve Circulatory System 0.778 0.62 – 0.977 0.0306 90 546 exclusion phecode
395 Heart valve disorders Circulatory System 0.885 0.809 – 0.968 0.00755 658 2974 exclusion phecode
395.1 Nonrheumatic mitral valve disorders Circulatory System 0.868 0.776 – 0.969 0.012 400 2315 exclusion phecode
395.2 Nonrheumatic aortic valve disorders Circulatory System 0.819 0.722 – 0.929 0.00196 327 1569 exclusion phecode
395.3 Nonrheumatic tricuspid valve disorders Circulatory System 0.897 0.708 – 1.14 0.366 82 497 exclusion phecode
395.4 Nonrheumatic pulmonary valve disorders Circulatory System 0.565 0.293 – 1.09 0.0889 13 98 exclusion phecode
395.6 Heart valve replaced Circulatory System 0.895 0.75 – 1.07 0.219 156 831 exclusion phecode
396 Abnormal heart sounds Circulatory System 0.936 0.867 – 1.01 0.0873 866 3680 exclusion phecode
401 Hypertension Circulatory System 0.993 0.932 – 1.06 0.818 2512 2711 exclusion phecode
401.1 Essential hypertension Circulatory System 0.993 0.932 – 1.06 0.825 2494 2710 exclusion phecode
401.2 Hypertensive heart and/or renal disease Circulatory System 0.958 0.852 – 1.08 0.478 416 1727 exclusion phecode
401.21 Hypertensive heart disease Circulatory System 0.9 0.732 – 1.11 0.317 123 754 exclusion phecode
401.22 Hypertensive chronic kidney disease Circulatory System 1.01 0.889 – 1.16 0.833 296 1507 exclusion phecode
401.3 Other hypertensive complications Circulatory System 1.02 0.915 – 1.15 0.678 418 1908 exclusion phecode
411 Ischemic Heart Disease Circulatory System 0.943 0.872 – 1.02 0.134 991 3370 exclusion phecode
411.1 Unstable angina (intermediate coronary syndrome) Circulatory System 1.07 0.875 – 1.32 0.495 95 788 exclusion phecode
411.2 Myocardial infarction Circulatory System 0.916 0.804 – 1.04 0.183 272 2226 exclusion phecode
411.3 Angina pectoris Circulatory System 0.903 0.792 – 1.03 0.13 270 1861 exclusion phecode
411.4 Coronary atherosclerosis Circulatory System 0.919 0.845 – 0.998 0.0446 845 3061 exclusion phecode
411.41 Aneurysm and dissection of heart Circulatory System 0.873 0.509 – 1.5 0.622 18 140 exclusion phecode
411.8
Other chronic ischemic heart disease
Other chronic ischemic heart disease, unspecified
 Circulatory System 0.891 0.81 – 0.981 0.0181 589 2783 exclusion phecode
411.9
Other acute and subacute forms of ischemic
Other acute and subacute forms of ischemic heart disease
 Circulatory System 0.908 0.702 – 1.17 0.46 66 442 exclusion phecode
414 Other forms of chronic heart disease Circulatory System 0.973 0.877 – 1.08 0.61 454 2413 exclusion phecode
414.2 ASCVD Circulatory System 0.975 0.791 – 1.2 0.816 100 647 exclusion phecode
415 Pulmonary heart disease Circulatory System 0.991 0.888 – 1.11 0.874 376 3259 exclusion phecode
415.1 Acute pulmonary heart disease Circulatory System 0.984 0.845 – 1.15 0.837 182 2016 exclusion phecode
415.11 Pulmonary embolism and infarction, acute Circulatory System 0.985 0.846 – 1.15 0.844 182 2014 exclusion phecode
415.2 Chronic pulmonary heart disease Circulatory System 0.977 0.853 – 1.12 0.743 239 1954 exclusion phecode
415.21 Primary pulmonary hypertension Circulatory System 1.01 0.816 – 1.25 0.934 89 808 exclusion phecode
416 Cardiomegaly Circulatory System 1.02 0.881 – 1.19 0.764 208 1330 exclusion phecode
418 Nonspecific chest pain Circulatory System 1.02 0.967 – 1.09 0.402 2336 2873 exclusion phecode
418.1 Precordial pain Circulatory System 0.973 0.848 – 1.12 0.691 273 1205 exclusion phecode
420 Carditis Circulatory System 1.05 0.916 – 1.21 0.468 232 1638 exclusion phecode
420.1 Myocarditis Circulatory System 1.5 0.84 – 2.69 0.17 16 88 exclusion phecode
420.2 Pericarditis Circulatory System 1.08 0.891 – 1.3 0.446 128 890 exclusion phecode
420.21 Acute pericarditis Circulatory System 1.05 0.72 – 1.52 0.809 34 180 exclusion phecode
420.22 Chronic pericarditis Circulatory System 0.777 0.418 – 1.44 0.423 13 124 exclusion phecode
420.3 Endocarditis Circulatory System 0.977 0.798 – 1.19 0.817 108 792 exclusion phecode
425 Cardiomyopathy Circulatory System 0.932 0.813 – 1.07 0.309 245 1935 exclusion phecode
425.1 Primary/intrinsic cardiomyopathies Circulatory System 0.911 0.792 – 1.05 0.189 236 1836 exclusion phecode
425.11 Hypertrophic obstructive cardiomyopathy Circulatory System 0.858 0.553 – 1.33 0.494 20 193 exclusion phecode
425.12 Other hypertrophic cardiomyopathy Circulatory System 0.632 0.423 – 0.945 0.0255 24 218 exclusion phecode
425.2 Secondary/extrinsic cardiomyopathies Circulatory System 1.36 0.967 – 1.92 0.0774 32 299 exclusion phecode
425.8 Other cardiomyopathy Circulatory System 0.785 0.475 – 1.3 0.346 18 102 exclusion phecode
426 Cardiac conduction disorders Circulatory System 0.92 0.857 – 0.986 0.0187 1816 2171 exclusion phecode
426.2 Atrioventricular [AV] block Circulatory System 1.01 0.859 – 1.19 0.88 214 800 exclusion phecode
426.21 First degree AV block Circulatory System 1.06 0.868 – 1.31 0.547 126 582 exclusion phecode
426.22 Mobitz II AV block Circulatory System 1.47 0.676 – 3.18 0.333 12 39 exclusion phecode
426.23 Second degree AV block Circulatory System 1.07 0.71 – 1.62 0.743 30 120 exclusion phecode
426.24 Atrioventricular block, complete Circulatory System 0.905 0.65 – 1.26 0.554 59 243 exclusion phecode
426.25 Other heart block Circulatory System 0.83 0.509 – 1.35 0.454 34 108 exclusion phecode
426.3 Bundle branch block Circulatory System 0.963 0.835 – 1.11 0.601 268 1065 exclusion phecode
426.31 Right bundle branch block Circulatory System 0.913 0.763 – 1.09 0.323 158 746 exclusion phecode
426.32 Left bundle branch block Circulatory System 1.05 0.86 – 1.29 0.612 118 598 exclusion phecode
426.4 Anomalous atrioventricular excitation Circulatory System 0.622 0.248 – 1.56 0.31 7 47 exclusion phecode
426.7 Abnormal electrocardiogram [ECG] [EKG] Circulatory System 0.921 0.857 – 0.989 0.0244 1672 2168 exclusion phecode
426.8 Other cardiac conduction disorders Circulatory System 0.773 0.626 – 0.954 0.0166 107 557 exclusion phecode
426.9 Cardiac pacemaker/device in situ Circulatory System 0.935 0.774 – 1.13 0.488 163 779 exclusion phecode
426.91 Cardiac pacemaker in situ Circulatory System 0.997 0.797 – 1.25 0.982 115 530 exclusion phecode
426.92 Cardiac defibrillator in situ Circulatory System 0.809 0.618 – 1.06 0.124 77 438 exclusion phecode
427 Cardiac dysrhythmias Circulatory System 0.965 0.907 – 1.03 0.249 2553 2199 exclusion phecode
427.1 Paroxysmal tachycardia, unspecified Circulatory System 0.946 0.836 – 1.07 0.381 365 1471 exclusion phecode
427.11 Paroxysmal supraventricular tachycardia Circulatory System 0.921 0.797 – 1.06 0.266 260 1166 exclusion phecode
427.12 Paroxysmal ventricular tachycardia Circulatory System 0.85 0.699 – 1.03 0.103 143 683 exclusion phecode
427.2 Atrial fibrillation and flutter Circulatory System 0.934 0.836 – 1.04 0.226 598 1505 exclusion phecode
427.21 Atrial fibrillation Circulatory System 0.946 0.845 – 1.06 0.33 582 1477 exclusion phecode
427.22 Atrial flutter Circulatory System 0.936 0.789 – 1.11 0.451 222 714 exclusion phecode
427.3 Other specified cardiac dysrhythmias Circulatory System 0.969 0.899 – 1.04 0.417 1316 2163 exclusion phecode
427.4 Cardiac arrest and ventricular fibrillation Circulatory System 1.04 0.763 – 1.41 0.822 49 352 exclusion phecode
427.41 Ventricular fibrillation and flutter Circulatory System 1.14 0.692 – 1.89 0.602 17 147 exclusion phecode
427.42 Cardiac arrest Circulatory System 0.94 0.668 – 1.32 0.724 40 276 exclusion phecode
427.5 Arrhythmia (cardiac) NOS Circulatory System 0.971 0.894 – 1.05 0.477 1027 2157 exclusion phecode
427.6 Premature beats Circulatory System 0.925 0.82 – 1.04 0.202 406 1395 exclusion phecode
427.61 Supraventricular premature beats Circulatory System 0.986 0.807 – 1.21 0.894 133 534 exclusion phecode
427.7 Tachycardia NOS Circulatory System 0.967 0.886 – 1.06 0.46 737 2171 exclusion phecode
427.8 Sinoatrial node dysfunction (Bradycardia) Circulatory System 0.944 0.777 – 1.15 0.563 155 513 exclusion phecode
427.9 Palpitations Circulatory System 0.927 0.859 – 1 0.056 1121 2166 exclusion phecode
428 Congestive heart failure; nonhypertensive Circulatory System 0.891 0.801 – 0.991 0.0335 496 2126 exclusion phecode
428.1 Congestive heart failure (CHF) NOS Circulatory System 0.892 0.797 – 0.999 0.0475 427 1978 exclusion phecode
428.2 Heart failure NOS Circulatory System 0.913 0.812 – 1.03 0.128 394 1898 exclusion phecode
428.3
Heart failure with reduced EF [Systolic or
Heart failure with reduced EF [Systolic or combined heart failure]
 Circulatory System 0.778 0.661 – 0.916 0.00254 196 1090 exclusion phecode
428.4
Heart failure with preserved EF [Diastolic
Heart failure with preserved EF [Diastolic heart failure]
 Circulatory System 0.835 0.712 – 0.98 0.0274 210 1136 exclusion phecode
429
Ill-defined descriptions and complications of
Ill-defined descriptions and complications of heart disease
 Circulatory System 0.993 0.936 – 1.05 0.813 2081 3018 exclusion phecode
429.1 Heart transplant/surgery Circulatory System 0.932 0.781 – 1.11 0.435 155 845 exclusion phecode
429.2 Abnormal function study of cardiovascular system Circulatory System 0.978 0.905 – 1.06 0.579 994 2802 exclusion phecode
429.3 Symptoms involving cardiovascular system Circulatory System 0.991 0.931 – 1.06 0.78 1659 3020 exclusion phecode
429.9 Cardiac complications, not elsewhere classified Circulatory System 0.881 0.697 – 1.11 0.287 88 474 exclusion phecode
430 Intracranial hemorrhage Circulatory System 1.03 0.828 – 1.29 0.764 101 790 exclusion phecode
430.1 Subarachnoid hemorrhage Circulatory System 0.951 0.652 – 1.39 0.794 40 265 exclusion phecode
430.2 Intracerebral hemorrhage Circulatory System 1.07 0.786 – 1.47 0.656 50 377 exclusion phecode
430.3 Subdural hemorrhage Circulatory System 1.38 0.913 – 2.09 0.127 33 246 exclusion phecode
433 Cerebrovascular disease Circulatory System 1.01 0.931 – 1.1 0.752 702 3606 exclusion phecode
433.1 Occlusion and stenosis of precerebral arteries Circulatory System 0.952 0.834 – 1.09 0.466 277 1710 exclusion phecode
433.11
Occlusion of cerebral arteries, with cerebral
Occlusion of cerebral arteries, with cerebral infarction
 Circulatory System 0.74 0.508 – 1.08 0.116 31 277 exclusion phecode
433.12 Cerebral atherosclerosis Circulatory System 0.808 0.377 – 1.73 0.583 8 72 exclusion phecode
433.2 Occlusion of cerebral arteries Circulatory System 1 0.88 – 1.14 0.981 263 2347 exclusion phecode
433.21
Cerebral artery occlusion, with cerebral
Cerebral artery occlusion, with cerebral infarction
 Circulatory System 1.01 0.887 – 1.15 0.867 255 2267 exclusion phecode
433.3 Cerebral ischemia Circulatory System 1.05 0.938 – 1.18 0.394 364 2507 exclusion phecode
433.31 Transient cerebral ischemia Circulatory System 1.02 0.902 – 1.16 0.741 294 2279 exclusion phecode
433.5 Cerebral aneurysm Circulatory System 1.01 0.766 – 1.33 0.954 62 599 exclusion phecode
433.6 Acute, but ill-defined cerebrovascular disease Circulatory System 0.792 0.609 – 1.03 0.0818 67 499 exclusion phecode
433.8 Late effects of cerebrovascular disease Circulatory System 0.872 0.702 – 1.08 0.215 93 718 exclusion phecode
440 Atherosclerosis Circulatory System 0.976 0.866 – 1.1 0.682 352 1848 exclusion phecode
440.1 Atherosclerosis of renal artery Circulatory System 0.922 0.661 – 1.29 0.632 41 251 exclusion phecode
440.2 Atherosclerosis of the extremities Circulatory System 0.977 0.839 – 1.14 0.763 200 1253 exclusion phecode
440.21
Atherosclerosis of native arteries of the
Atherosclerosis of native arteries of the extremities with ulceration or gangrene
 Circulatory System 0.818 0.547 – 1.22 0.325 31 241 exclusion phecode
440.22
Atherosclerosis of native arteries of the
Atherosclerosis of native arteries of the extremities with intermittent claudication
 Circulatory System 1.01 0.857 – 1.2 0.87 161 930 exclusion phecode
440.9 Atherosclerosis of aorta Circulatory System 1.02 0.835 – 1.24 0.862 124 715 exclusion phecode
441 Vascular insufficiency of intestine Circulatory System 0.949 0.728 – 1.24 0.696 70 531 exclusion phecode
441.1 Acute vascular insufficiency of intestine Circulatory System 0.877 0.603 – 1.28 0.493 40 253 exclusion phecode
441.2 Chronic vascular insufficiency of intestine Circulatory System 0.712 0.429 – 1.18 0.187 18 168 exclusion phecode
442 Other aneurysm Circulatory System 0.895 0.793 – 1.01 0.0694 347 1899 exclusion phecode
442.1 Aortic aneurysm Circulatory System 0.859 0.747 – 0.988 0.0334 262 1328 exclusion phecode
442.11 Abdominal aortic aneurysm Circulatory System 0.865 0.716 – 1.04 0.131 138 788 exclusion phecode
442.2 Aneurysm of iliac artery Circulatory System 1.2 0.695 – 2.07 0.515 17 116 exclusion phecode
442.3 Aneurysm of artery of lower extremity Circulatory System 1.2 0.685 – 2.09 0.529 16 117 exclusion phecode
442.4 Arterial dissection Circulatory System 0.863 0.539 – 1.38 0.54 23 130 exclusion phecode
442.8 Aneurysm of other specified artery Circulatory System 0.872 0.647 – 1.17 0.366 59 382 exclusion phecode
443 Peripheral vascular disease Circulatory System 0.986 0.892 – 1.09 0.786 484 2557 exclusion phecode
443.1 Raynaud's syndrome Circulatory System 1.11 0.951 – 1.29 0.188 199 959 exclusion phecode
443.7
Peripheral angiopathy in diseases classified
Peripheral angiopathy in diseases classified elsewhere
 Circulatory System 0.944 0.609 – 1.46 0.795 27 230 exclusion phecode
443.8 Other specified peripheral vascular diseases Circulatory System 0.985 0.883 – 1.1 0.792 392 2221 exclusion phecode
443.9 Peripheral vascular disease, unspecified Circulatory System 0.927 0.816 – 1.05 0.244 295 1798 exclusion phecode
444 Arterial embolism and thrombosis Circulatory System 1.04 0.857 – 1.27 0.665 115 770 exclusion phecode
444.1
Arterial embolism and thrombosis of lower
Arterial embolism and thrombosis of lower extremity artery
 Circulatory System 0.875 0.635 – 1.2 0.413 43 277 exclusion phecode
444.2 Embolism and thrombosis of abdominal aorta Circulatory System 0.911 0.583 – 1.42 0.684 21 136 exclusion phecode
446 Polyarteritis nodosa and allied conditions Circulatory System 0.959 0.763 – 1.2 0.717 86 496 exclusion phecode
446.4 Wegener's granulomatosis Circulatory System 0.924 0.553 – 1.54 0.763 18 118 exclusion phecode
446.5 Giant cell arteritis Circulatory System 0.903 0.556 – 1.47 0.679 23 86 exclusion phecode
446.9 Arteritis NOS Circulatory System 0.815 0.613 – 1.08 0.161 55 309 exclusion phecode
447 Other disorders of arteries and arterioles Circulatory System 0.865 0.772 – 0.969 0.0124 376 2081 exclusion phecode
447.1 Stricture of artery Circulatory System 0.824 0.633 – 1.07 0.151 70 476 exclusion phecode
447.7 Aortic ectasia Circulatory System 0.874 0.716 – 1.07 0.185 124 580 exclusion phecode
448 Disease of capillaries Circulatory System 1.08 0.961 – 1.22 0.194 338 1479 exclusion phecode
450 Noninfectious disorders of lymphatic channels Circulatory System 1.12 0.994 – 1.26 0.0622 323 2755 exclusion phecode
451 Phlebitis and thrombophlebitis Circulatory System 1.05 0.859 – 1.29 0.616 123 642 exclusion phecode
451.2
Phlebitis and thrombophlebitis of lower
Phlebitis and thrombophlebitis of lower extremities
 Circulatory System 1.04 0.729 – 1.48 0.832 42 223 exclusion phecode
452 Other venous embolism and thrombosis Circulatory System 0.974 0.883 – 1.08 0.606 520 2491 exclusion phecode
452.1 Iatrogenic pulmonary embolism and infarction Circulatory System 0.772 0.535 – 1.11 0.165 30 234 exclusion phecode
452.2 Deep vein thrombosis [DVT] Circulatory System 0.979 0.872 – 1.1 0.721 350 2250 exclusion phecode
452.8 Postphlebitic syndrome Circulatory System 0.779 0.42 – 1.45 0.429 10 114 exclusion phecode
453 Chronic venous hypertension Circulatory System 0.828 0.613 – 1.12 0.22 61 241 exclusion phecode
454 Varicose veins Circulatory System 0.987 0.898 – 1.08 0.788 602 2233 exclusion phecode
454.1 Varicose veins of lower extremity Circulatory System 0.981 0.892 – 1.08 0.697 585 2097 exclusion phecode
454.11 Varicose veins of lower extremity, symptomtic Circulatory System 0.972 0.864 – 1.09 0.63 383 1513 exclusion phecode
455 Hemorrhoids Circulatory System 1.04 0.971 – 1.12 0.252 1391 2638 exclusion phecode
456 Chronic venous insufficiency [CVI] Circulatory System 0.988 0.903 – 1.08 0.803 657 2326 exclusion phecode
457
Encounter for long-term (current) use of
Encounter for long-term (current) use of anticoagulants, antithrombotics, aspirin
 Circulatory System 0.968 0.83 – 1.13 0.675 211 1156 exclusion phecode
457.2
Encounter for long-term (current) use of
Encounter for long-term (current) use of antiplatelets/antithrombotics
 Circulatory System 1.01 0.636 – 1.61 0.957 26 198 exclusion phecode
457.3 Encounter for long-term (current) use of aspirin Circulatory System 0.961 0.821 – 1.12 0.617 197 1120 exclusion phecode
458 Hypotension Circulatory System 0.977 0.899 – 1.06 0.589 707 3399 exclusion phecode
458.1 Orthostatic hypotension Circulatory System 0.979 0.849 – 1.13 0.774 229 1288 exclusion phecode
458.2 Iatrogenic hypotension Circulatory System 0.959 0.803 – 1.15 0.646 141 1064 exclusion phecode
458.9 Hypotension NOS Circulatory System 0.957 0.877 – 1.05 0.33 638 3287 exclusion phecode
459 Other disorders of circulatory system Circulatory System 0.974 0.905 – 1.05 0.49 978 3666 exclusion phecode
459.1 Hemorrhage NOS Circulatory System 0.971 0.813 – 1.16 0.748 146 941 exclusion phecode
459.7 Blood vessel replaced Circulatory System 0.971 0.812 – 1.16 0.749 130 1183 exclusion phecode
459.9 Circulatory disease NEC Circulatory System 0.984 0.908 – 1.07 0.7 804 3534 exclusion phecode
464 Acute sinusitis Respiratory 1.09 1.01 – 1.17 0.0225 1295 2441 exclusion phecode
465
Acute upper respiratory infections of multiple
Acute upper respiratory infections of multiple or unspecified sites
 Respiratory 1.06 1 – 1.13 0.0428 2323 2584 exclusion phecode
465.2 Acute pharyngitis Respiratory 1.07 1 – 1.15 0.0504 1289 2441 exclusion phecode
465.4 Acute laryngitis and tracheitis Respiratory 0.975 0.779 – 1.22 0.821 106 393 exclusion phecode
470 Septal Deviations/Turbinate Hypertrophy Respiratory 1.11 0.971 – 1.26 0.127 264 1232 exclusion phecode
471 Nasal polyps Respiratory 1.09 0.871 – 1.37 0.441 84 435 exclusion phecode
472 Chronic pharyngitis and nasopharyngitis Respiratory 1.12 0.998 – 1.26 0.0538 379 1537 exclusion phecode
473 Diseases of the larynx and vocal cords Respiratory 0.989 0.894 – 1.09 0.832 485 1941 exclusion phecode
473.1 Chronic laryngitis Respiratory 0.897 0.486 – 1.66 0.729 16 55 exclusion phecode
473.3 Paralysis/spasm of vocal cords or larynx Respiratory 0.906 0.72 – 1.14 0.403 92 515 exclusion phecode
473.4 Voice disturbance Respiratory 0.993 0.887 – 1.11 0.904 379 1721 exclusion phecode
474 Acute and chronic tonsillitis Respiratory 1.13 0.934 – 1.37 0.208 135 615 exclusion phecode
474.1 Acute tonsillitis Respiratory 1.35 1 – 1.82 0.049 58 222 exclusion phecode
474.2 Chronic tonsillitis and adenoiditis Respiratory 1.13 0.904 – 1.41 0.282 95 471 exclusion phecode
475 Chronic sinusitis Respiratory 1.07 0.989 – 1.16 0.091 894 2139 exclusion phecode
475.9 Postnasal drip Respiratory 1.14 0.978 – 1.34 0.0924 226 859 exclusion phecode
476 Allergic rhinitis Respiratory 1.07 1 – 1.14 0.0351 2323 2158 exclusion phecode
477 Epistaxis or throat hemorrhage Respiratory 0.972 0.835 – 1.13 0.717 195 897 exclusion phecode
478 Throat pain Respiratory 0.815 0.61 – 1.09 0.166 66 328 exclusion phecode
479 Other upper respiratory disease Respiratory 1.14 1.05 – 1.23 0.00116 944 2149 exclusion phecode
480 Pneumonia Respiratory 1.01 0.938 – 1.09 0.763 903 3545 exclusion phecode
480.1 Bacterial pneumonia Respiratory 0.944 0.811 – 1.1 0.46 207 1079 exclusion phecode
480.11 Pneumococcal pneumonia Respiratory 0.879 0.718 – 1.08 0.211 117 532 exclusion phecode
480.12 Pseudomonal pneumonia Respiratory 0.9 0.563 – 1.44 0.658 20 140 exclusion phecode
480.13 MRSA pneumonia Respiratory 1.52 0.783 – 2.95 0.216 8 115 exclusion phecode
480.2 Viral pneumonia Respiratory 0.733 0.513 – 1.05 0.0871 40 184 exclusion phecode
480.3 Pneumonia due to fungus (mycoses) Respiratory 1.15 0.721 – 1.83 0.56 33 129 exclusion phecode
480.5 Bronchopneumonia and lung abscess Respiratory 1.42 0.828 – 2.43 0.204 14 130 exclusion phecode
481 Influenza Respiratory 1 0.883 – 1.14 0.976 312 1562 exclusion phecode
483 Acute bronchitis and bronchiolitis Respiratory 1.05 0.97 – 1.14 0.227 810 3226 exclusion phecode
495 Asthma Respiratory 1.02 0.959 – 1.1 0.47 1252 3425 exclusion phecode
495.1 Chronic obstructive asthma Respiratory 0.95 0.738 – 1.22 0.69 72 507 exclusion phecode
495.11 Chronic obstructive asthma with exacerbation Respiratory 1.01 0.628 – 1.61 0.978 20 132 exclusion phecode
495.2 Asthma with exacerbation Respiratory 1.14 1.02 – 1.28 0.0198 373 2074 exclusion phecode
496 Chronic airway obstruction Respiratory 0.987 0.898 – 1.08 0.79 556 2919 exclusion phecode
496.1 Emphysema Respiratory 0.944 0.821 – 1.08 0.413 232 1816 exclusion phecode
496.2 Chronic bronchitis Respiratory 0.976 0.878 – 1.08 0.647 425 2733 exclusion phecode
496.21 Obstructive chronic bronchitis Respiratory 0.989 0.887 – 1.1 0.844 389 2604 exclusion phecode
496.3 Bronchiectasis Respiratory 1.12 0.899 – 1.39 0.317 108 619 exclusion phecode
497 Bronchitis Respiratory 0.98 0.885 – 1.08 0.693 457 2394 exclusion phecode
498 Acute bronchospasm Respiratory 1.23 1 – 1.52 0.0457 114 614 exclusion phecode
499 Cystic fibrosis Respiratory 1.4 0.98 – 1.99 0.0645 39 232 exclusion phecode
500 Lung disease due to external agents Respiratory 1.01 0.788 – 1.28 0.965 72 585 exclusion phecode
500.1 Extrinsic allergic alveolitis Respiratory 0.959 0.593 – 1.55 0.863 22 137 exclusion phecode
500.2 Pneumoconiosis Respiratory 0.454 0.189 – 1.09 0.0768 8 56 exclusion phecode
501 Pneumonitis due to inhalation of food or vomitus Respiratory 0.737 0.578 – 0.942 0.0146 76 559 exclusion phecode
502 Postinflammatory pulmonary fibrosis Respiratory 0.954 0.789 – 1.15 0.63 125 848 exclusion phecode
503 Pulmonary congestion and hypostasis Respiratory 0.832 0.675 – 1.03 0.0842 104 824 exclusion phecode
504 Other alveolar and parietoalveolar pneumonopathy Respiratory 0.966 0.783 – 1.19 0.746 103 673 exclusion phecode
504.1 Idiopathic fibrosing alveolitis Respiratory 0.96 0.721 – 1.28 0.778 54 341 exclusion phecode
505 Other pulmonary inflamation or edema Respiratory 0.998 0.861 – 1.16 0.984 209 1606 exclusion phecode
506 Empyema and pneumothorax Respiratory 0.874 0.772 – 0.988 0.032 304 2372 exclusion phecode
507 Pleurisy; pleural effusion Respiratory 1 0.895 – 1.12 0.993 361 2708 exclusion phecode
508
Pulmonary collapse; interstitial and
Pulmonary collapse; interstitial and compensatory emphysema
 Respiratory 0.957 0.839 – 1.09 0.511 259 2311 exclusion phecode
509 Respiratory failure, insufficiency, arrest Respiratory 0.909 0.821 – 1.01 0.0678 462 3044 exclusion phecode
509.1 Respiratory failure Respiratory 0.944 0.821 – 1.09 0.418 236 1873 exclusion phecode
509.2 Respiratory insufficiency Respiratory 0.925 0.779 – 1.1 0.372 146 1056 exclusion phecode
509.3
Pulmonary insufficiency or respiratory failure
Pulmonary insufficiency or respiratory failure following trauma and surgery
 Respiratory 0.889 0.763 – 1.04 0.131 199 1430 exclusion phecode
509.8
Dependence on respirator [Ventilator] or
Dependence on respirator [Ventilator] or supplemental oxygen
 Respiratory 0.903 0.778 – 1.05 0.183 195 1736 exclusion phecode
510 Other diseases of lung Respiratory 0.995 0.923 – 1.07 0.904 896 3832 exclusion phecode
510.2 Lung transplant Respiratory 1.15 0.801 – 1.66 0.442 41 141 exclusion phecode
512 Other symptoms of respiratory system Respiratory 1.07 1 – 1.13 0.0337 3144 2087 exclusion phecode
512.1 Wheezing Respiratory 1.05 0.923 – 1.2 0.445 292 1192 exclusion phecode
512.2 Painful respiration Respiratory 1.06 0.959 – 1.18 0.247 499 1744 exclusion phecode
512.3 Abnormal chest sounds Respiratory 1.15 0.808 – 1.63 0.441 48 193 exclusion phecode
512.7 Shortness of breath Respiratory 1.05 0.982 – 1.13 0.146 1681 2082 exclusion phecode
512.8 Cough Respiratory 1.08 1.01 – 1.15 0.0271 2035 2087 exclusion phecode
512.9 Other dyspnea Respiratory 1.06 0.992 – 1.14 0.0828 1712 2083 exclusion phecode
513 Respiratory abnormalities Respiratory 1.01 0.955 – 1.07 0.683 1995 3235 exclusion phecode
513.3 Hypoventilation Respiratory 1.08 0.892 – 1.31 0.431 128 865 exclusion phecode
513.31 Apnea Respiratory 1.03 0.805 – 1.31 0.824 82 423 exclusion phecode
513.32 Orthopnea Respiratory 0.843 0.53 – 1.34 0.472 22 181 exclusion phecode
513.4 Hyperventilation Respiratory 1.15 0.897 – 1.47 0.273 83 445 exclusion phecode
513.8 Disorders of diaphragm Respiratory 1.12 0.75 – 1.67 0.581 33 190 exclusion phecode
514 Abnormal findings examination of lungs Respiratory 0.997 0.917 – 1.08 0.953 721 3789 exclusion phecode
514.1
Abnormal results of function study of pulmonary
Abnormal results of function study of pulmonary system
 Respiratory 0.902 0.681 – 1.2 0.474 58 296 exclusion phecode
514.2 Solitary pulmonary nodule Respiratory 1.01 0.908 – 1.12 0.871 414 2978 exclusion phecode
516 Abnormal sputum Respiratory 0.937 0.755 – 1.16 0.552 101 761 exclusion phecode
516.1 Hemoptysis Respiratory 0.947 0.748 – 1.2 0.649 82 631 exclusion phecode
519
Other diseases of respiratory system, not
Other diseases of respiratory system, not elsewhere classified
 Respiratory 0.963 0.896 – 1.04 0.313 959 4138 exclusion phecode
519.1 Tracheostomy complications Respiratory 1.26 0.737 – 2.15 0.4 13 180 exclusion phecode
519.2 Respiratory complications Respiratory 0.704 0.506 – 0.98 0.0374 46 351 exclusion phecode
519.8 Other diseases of respiratory system, NEC Respiratory 0.97 0.851 – 1.1 0.643 258 1784 exclusion phecode
519.9
Symptoms involving respiratory system and other
Symptoms involving respiratory system and other chest symptoms
 Respiratory 0.947 0.87 – 1.03 0.209 675 3623 exclusion phecode
520 Disorders of tooth development Digestive 1.04 0.692 – 1.56 0.853 22 325 exclusion phecode
520.1 Hereditary disturbances in tooth structure Digestive 0.997 0.557 – 1.79 0.993 11 167 exclusion phecode
520.2 Disturbances in tooth eruption Digestive 0.99 0.584 – 1.68 0.971 11 162 exclusion phecode
521 Diseases of hard tissues of teeth Digestive 0.949 0.732 – 1.23 0.696 64 826 exclusion phecode
521.1 Dental caries Digestive 1.01 0.77 – 1.32 0.95 59 768 exclusion phecode
521.2 Dental abrasion, erosion and attrition Digestive 0.671 0.195 – 2.31 0.527 6 49 exclusion phecode
522 Diseases of pulp and periapical tissues Digestive 1.07 0.814 – 1.4 0.632 50 556 exclusion phecode
522.5 Periapical abscess Digestive 1.08 0.803 – 1.44 0.621 45 481 exclusion phecode
523 Gingival and periodontal diseases Digestive 1.28 1.01 – 1.62 0.0429 80 739 exclusion phecode
523.1 Gingivitis Digestive 1.37 0.834 – 2.24 0.215 19 141 exclusion phecode
523.3 Periodontitis (acute or chronic) Digestive 1.18 0.83 – 1.68 0.357 32 361 exclusion phecode
523.31 Acute periodontitis Digestive 1.36 0.92 – 2.02 0.123 27 304 exclusion phecode
523.32 Chronic periodontitis Digestive 0.845 0.409 – 1.74 0.648 9 111 exclusion phecode
524 Dentofacial anomalies, including malocclusion Digestive 1.16 0.802 – 1.67 0.437 32 309 exclusion phecode
524.3 Anomalies of tooth position/malocclusion Digestive 1.36 0.874 – 2.12 0.173 20 165 exclusion phecode
525
Other diseases of the teeth and supporting
Other diseases of the teeth and supporting structures
 Digestive 1.13 0.934 – 1.36 0.213 121 1093 exclusion phecode
525.1 Loss of teeth or edentulism Digestive 1.15 0.819 – 1.62 0.418 32 379 exclusion phecode
526 Diseases of the jaws Digestive 0.944 0.852 – 1.05 0.271 433 3099 exclusion phecode
526.1 Cysts of the jaws Digestive 0.708 0.403 – 1.25 0.232 12 180 exclusion phecode
526.3 Anomalies of jaw size/symmetry Digestive 1.1 0.711 – 1.69 0.679 25 182 exclusion phecode
526.4 Temporomandibular joint disorders Digestive 0.94 0.831 – 1.06 0.323 298 1947 exclusion phecode
526.41 Temporomandibular joint disorder, unspecified Digestive 0.894 0.773 – 1.03 0.129 226 1567 exclusion phecode
526.42 Arthralgia/ankylosis of temporomandibular joint Digestive 1.09 0.909 – 1.3 0.355 136 934 exclusion phecode
526.5 Inflammatory conditions of jaw Digestive 1.18 0.735 – 1.89 0.494 23 298 exclusion phecode
526.8 Exostosis of jaw Digestive 0.887 0.405 – 1.94 0.764 9 60 exclusion phecode
526.9 Jaw disease NOS Digestive 1.01 0.772 – 1.33 0.926 64 528 exclusion phecode
527 Diseases of the salivary glands Digestive 1.06 0.929 – 1.21 0.38 239 1840 exclusion phecode
527.1 Hypertrophy of salivary gland Digestive 0.861 0.391 – 1.9 0.709 5 71 exclusion phecode
527.2 Sialoadenitis Digestive 1.09 0.839 – 1.42 0.518 61 453 exclusion phecode
527.7 Disturbance of salivary secretion Digestive 1.04 0.874 – 1.24 0.638 131 1000 exclusion phecode
527.8 Other specified diseases of the salivary glands Digestive 1.26 0.854 – 1.85 0.245 29 256 exclusion phecode
528
Diseases of the oral soft tissues, excluding
Diseases of the oral soft tissues, excluding lesions specific for gingiva and tongue
 Digestive 1.06 0.953 – 1.17 0.292 425 2966 exclusion phecode
528.1 Stomatitis and mucositis Digestive 1.1 0.911 – 1.33 0.317 126 804 exclusion phecode
528.11 Stomatitis and mucositis (ulcerative) Digestive 1.27 0.895 – 1.79 0.182 37 246 exclusion phecode
528.12 Oral aphthae Digestive 0.924 0.693 – 1.23 0.593 56 307 exclusion phecode
528.3 Cellulitis and abscess of oral soft tissues Digestive 1.15 0.736 – 1.79 0.541 25 211 exclusion phecode
528.4 Cysts of oral soft tissues Digestive 1.66 0.944 – 2.91 0.0783 17 134 exclusion phecode
528.41 Cyst of the salivary gland Digestive 2.52 1.1 – 5.79 0.0295 11 73 exclusion phecode
528.5 Diseases of lips Digestive 0.994 0.8 – 1.24 0.96 109 590 exclusion phecode
528.6 Leukoplakia of oral mucosa Digestive 0.714 0.388 – 1.32 0.28 12 139 exclusion phecode
528.7 Sialolithiasis Digestive 1.01 0.683 – 1.51 0.943 22 177 exclusion phecode
529 Diseases and other conditions of the tongue Digestive 0.796 0.647 – 0.981 0.032 107 741 exclusion phecode
529.1 Glossitis Digestive 0.579 0.356 – 0.943 0.028 25 155 exclusion phecode
529.6 Glossodynia Digestive 1.08 0.751 – 1.56 0.671 28 186 exclusion phecode
530 Diseases of esophagus Digestive 1.04 0.986 – 1.11 0.141 2358 2700 exclusion phecode
530.1 Esophagitis, GERD and related diseases Digestive 1.05 0.987 – 1.11 0.13 2311 2700 exclusion phecode
530.11 GERD Digestive 1.04 0.98 – 1.1 0.193 2249 2699 exclusion phecode
530.12 Ulcer of esophagus Digestive 1.3 0.981 – 1.73 0.0672 66 352 exclusion phecode
530.13 Barrett's esophagus Digestive 0.92 0.71 – 1.19 0.526 73 642 exclusion phecode
530.14 Reflux esophagitis Digestive 1.18 1.05 – 1.32 0.00561 381 1956 exclusion phecode
530.15 Eosinophilic esophagitis Digestive 1.09 0.784 – 1.5 0.618 55 234 exclusion phecode
530.2 Esophageal bleeding (varices/hemorrhage) Digestive 0.876 0.673 – 1.14 0.325 65 571 exclusion phecode
530.3 Stricture and stenosis of esophagus Digestive 1.07 0.887 – 1.29 0.486 133 888 exclusion phecode
530.5 Disorders of esophageal motility Digestive 1 0.794 – 1.26 0.994 88 606 exclusion phecode
530.6 Diverticulum of esophagus, acquired Digestive 1.66 0.715 – 3.85 0.239 8 95 exclusion phecode
530.7 Gastroesophageal laceration-hemorrhage syndrome Digestive 1.2 0.65 – 2.21 0.562 16 95 exclusion phecode
530.9 Heartburn Digestive 0.955 0.84 – 1.09 0.483 291 1747 exclusion phecode
531 Peptic ulcer (excl. esophageal) Digestive 1 0.89 – 1.13 0.948 314 2365 exclusion phecode
531.1 Hemorrhage from gastrointestinal ulcer Digestive 1.04 0.792 – 1.37 0.765 54 369 exclusion phecode
531.2 Gastric ulcer Digestive 1.04 0.892 – 1.22 0.596 188 1392 exclusion phecode
531.3 Duodenal ulcer Digestive 1.08 0.825 – 1.41 0.577 63 422 exclusion phecode
531.4 Peptic ulcer, site unspecified Digestive 0.932 0.785 – 1.11 0.421 156 999 exclusion phecode
531.5 Gastrojejunal ulcer Digestive 0.864 0.55 – 1.36 0.525 23 180 exclusion phecode
532 Dysphagia Digestive 1.06 0.976 – 1.15 0.161 807 2574 exclusion phecode
535 Gastritis and duodenitis Digestive 1.04 0.941 – 1.14 0.463 490 3089 exclusion phecode
535.1 Acute gastritis Digestive 1.06 0.904 – 1.24 0.486 187 1353 exclusion phecode
535.2 Atrophic gastritis Digestive 0.79 0.59 – 1.06 0.113 66 381 exclusion phecode
535.6 Duodenitis Digestive 0.88 0.634 – 1.22 0.447 47 297 exclusion phecode
535.8 Other specified gastritis Digestive 0.974 0.798 – 1.19 0.792 130 723 exclusion phecode
535.9 Gastritis and duodenitis, NOS Digestive 0.949 0.826 – 1.09 0.466 238 1458 exclusion phecode
536 Disorders of function of stomach Digestive 1.06 0.964 – 1.16 0.239 598 3192 exclusion phecode
536.3 Gastroparesis Digestive 1.09 0.894 – 1.33 0.396 121 904 exclusion phecode
536.7
Complications of gastrostomy, colostomy and
Complications of gastrostomy, colostomy and enterostomy
 Digestive 1.2 0.869 – 1.65 0.272 38 374 exclusion phecode
536.8
Dyspepsia and other specified disorders of
Dyspepsia and other specified disorders of function of stomach
 Digestive 1.03 0.933 – 1.14 0.549 497 2558 exclusion phecode
537 Other disorders of stomach and duodenum Digestive 1.04 0.95 – 1.15 0.373 523 3323 exclusion phecode
537.1 Lesions of stomach and duodenum Digestive 0.894 0.534 – 1.5 0.671 19 188 exclusion phecode
539 Bariatric surgery Digestive 0.958 0.838 – 1.09 0.529 240 2002 exclusion phecode
540 Appendiceal conditions Digestive 1.11 0.898 – 1.38 0.332 99 554 exclusion phecode
540.1 Appendicitis Digestive 1.18 0.926 – 1.5 0.181 81 448 exclusion phecode
540.11 Acute appendicitis Digestive 1.17 0.914 – 1.51 0.209 76 398 exclusion phecode
550 Abdominal hernia Digestive 1.09 1.02 – 1.18 0.0162 974 3990 exclusion phecode
550.1 Inguinal hernia Digestive 1.14 0.993 – 1.31 0.0636 267 993 exclusion phecode
550.2 Diaphragmatic hernia Digestive 1.09 0.983 – 1.2 0.102 462 3030 exclusion phecode
550.3 Femoral hernia Digestive 0.836 0.569 – 1.23 0.363 37 150 exclusion phecode
550.4 Umbilical hernia Digestive 1.07 0.894 – 1.27 0.472 150 1121 exclusion phecode
550.5 Ventral hernia Digestive 1.05 0.921 – 1.19 0.477 270 2271 exclusion phecode
550.6 Incisional hernia Digestive 0.973 0.819 – 1.16 0.76 151 1361 exclusion phecode
555
Inflammatory bowel disease and other
Inflammatory bowel disease and other gastroenteritis and colitis
 Digestive 1.03 0.88 – 1.2 0.73 202 1234 exclusion phecode
555.1 Regional enteritis Digestive 0.958 0.777 – 1.18 0.686 112 696 exclusion phecode
555.2 Ulcerative colitis Digestive 1.1 0.902 – 1.34 0.349 129 751 exclusion phecode
555.21 Ulcerative colitis (chronic) Digestive 1.18 0.927 – 1.51 0.175 79 413 exclusion phecode
556 Ulceration of the lower GI tract Digestive 0.986 0.799 – 1.22 0.897 112 528 exclusion phecode
556.1 Ulceration of intestine Digestive 1.02 0.817 – 1.28 0.843 100 476 exclusion phecode
556.11
Angiodysplasia of intestine (without mention of
Angiodysplasia of intestine (without mention of hemorrhage)
 Digestive 0.98 0.67 – 1.43 0.917 36 161 exclusion phecode
557 Intestinal malabsorption (non-celiac) Digestive 0.936 0.832 – 1.05 0.276 353 1640 exclusion phecode
557.1 Celiac disease Digestive 0.992 0.786 – 1.25 0.944 88 442 exclusion phecode
558 Noninfectious gastroenteritis Digestive 0.933 0.849 – 1.03 0.151 609 2176 exclusion phecode
559 Ileostomy status Digestive 1.06 0.829 – 1.35 0.644 78 593 exclusion phecode
560 Intestinal obstruction without mention of hernia Digestive 0.975 0.87 – 1.09 0.667 387 1868 exclusion phecode
560.1 Paralytic ileus Digestive 1 0.846 – 1.18 0.991 161 1005 exclusion phecode
560.2 Impaction of intestine Digestive 0.995 0.778 – 1.27 0.969 83 394 exclusion phecode
560.3 Peritoneal or intestinal adhesions Digestive 1.02 0.698 – 1.5 0.902 45 207 exclusion phecode
560.4 Other intestinal obstruction Digestive 1.01 0.865 – 1.18 0.908 227 1227 exclusion phecode
561 Symptoms involving digestive system Digestive 0.947 0.856 – 1.05 0.284 548 1970 exclusion phecode
562 Diverticulosis and diverticulitis Digestive 1.05 0.971 – 1.14 0.22 1305 1897 exclusion phecode
562.1 Diverticulosis Digestive 1.05 0.972 – 1.14 0.206 1299 1885 exclusion phecode
562.2 Diverticulitis Digestive 0.995 0.86 – 1.15 0.948 238 1227 exclusion phecode
564 Functional digestive disorders Digestive 1.02 0.954 – 1.09 0.597 1871 2279 exclusion phecode
564.1 Irritable Bowel Syndrome Digestive 1.02 0.936 – 1.12 0.605 700 2049 exclusion phecode
564.9 Personal history of diseases of digestive system Digestive 1.03 0.928 – 1.14 0.593 495 2025 exclusion phecode
565 Anal and rectal conditions Digestive 1.03 0.942 – 1.12 0.535 684 2992 exclusion phecode
565.1 Anal and rectal polyp Digestive 0.939 0.822 – 1.07 0.35 307 1275 exclusion phecode
567 Peritonitis and retroperitoneal infections Digestive 0.972 0.832 – 1.14 0.726 177 1106 exclusion phecode
568 Other disorders of peritoneum Digestive 0.999 0.847 – 1.18 0.991 165 1501 exclusion phecode
568.1
Peritoneal adhesions (postoperative)
Peritoneal adhesions (postoperative) (postinfection)
 Digestive 1 0.818 – 1.22 0.995 109 1104 exclusion phecode
569 Other disorders of intestine Digestive 1.04 0.97 – 1.11 0.286 1359 3341 exclusion phecode
569.1 Toxic gastroenteritis and colitis Digestive 1.25 0.901 – 1.73 0.183 40 324 exclusion phecode
569.2 Gastrointestinal complications Digestive 0.936 0.792 – 1.11 0.437 161 1257 exclusion phecode
571 Chronic liver disease and cirrhosis Digestive 0.94 0.854 – 1.04 0.21 507 3317 exclusion phecode
571.5 Other chronic nonalcoholic liver disease Digestive 0.946 0.858 – 1.04 0.27 481 3292 exclusion phecode
571.51 Cirrhosis of liver without mention of alcohol Digestive 0.859 0.692 – 1.07 0.169 92 967 exclusion phecode
571.6 Primary biliary cirrhosis Digestive 0.881 0.508 – 1.53 0.652 17 188 exclusion phecode
571.8
Liver abscess and sequelae of chronic liver
Liver abscess and sequelae of chronic liver disease
 Digestive 0.83 0.659 – 1.05 0.113 85 877 exclusion phecode
571.81 Portal hypertension Digestive 0.832 0.605 – 1.15 0.261 46 539 exclusion phecode
572 Ascites (non malignant) Digestive 0.943 0.829 – 1.07 0.373 271 2243 exclusion phecode
573 Other disorders of liver Digestive 0.95 0.874 – 1.03 0.226 722 3446 exclusion phecode
573.1 Chronic passive congestion of liver Digestive 0.445 0.238 – 0.831 0.0111 13 108 exclusion phecode
573.2 Liver replaced by transplant Digestive 1.07 0.754 – 1.52 0.699 43 240 exclusion phecode
573.3 Hepatomegaly Digestive 0.905 0.678 – 1.21 0.497 52 506 exclusion phecode
573.4 Acute and subacute necrosis of liver Digestive 0.966 0.668 – 1.4 0.854 42 284 exclusion phecode
573.5 Jaundice (not of newborn) Digestive 0.972 0.805 – 1.17 0.77 126 869 exclusion phecode
573.6
Nonspecific elevation of levels of transaminase
Nonspecific elevation of levels of transaminase or lactic acid dehydrogenase [LDH]
 Digestive 0.963 0.87 – 1.07 0.468 467 2683 exclusion phecode
573.7 Abnormal results of function study of liver Digestive 0.935 0.849 – 1.03 0.173 524 2906 exclusion phecode
573.9 Abnormal serum enzyme levels Digestive 0.939 0.867 – 1.02 0.122 787 3454 exclusion phecode
574 Cholelithiasis and cholecystitis Digestive 1.09 0.984 – 1.2 0.101 468 3627 exclusion phecode
574.1 Cholelithiasis Digestive 1.08 0.975 – 1.19 0.143 437 3472 exclusion phecode
574.11 Cholelithiasis with acute cholecystitis Digestive 1.33 0.983 – 1.79 0.0641 55 404 exclusion phecode
574.12 Cholelithiasis with other cholecystitis Digestive 1.24 0.995 – 1.55 0.0554 83 658 exclusion phecode
574.2 Calculus of bile duct Digestive 1.03 0.864 – 1.24 0.721 149 968 exclusion phecode
574.3 Cholecystitis without cholelithiasis Digestive 1.13 0.936 – 1.38 0.198 120 967 exclusion phecode
575 Other biliary tract disease Digestive 0.951 0.847 – 1.07 0.394 344 2636 exclusion phecode
575.1 Cholangitis Digestive 1.15 0.824 – 1.59 0.418 42 354 exclusion phecode
575.2 Obstruction of bile duct Digestive 0.899 0.705 – 1.15 0.39 75 651 exclusion phecode
575.6 Cholesterolosis of gallbladder Digestive 0.968 0.684 – 1.37 0.855 34 250 exclusion phecode
575.7 Other disorders of gallbladder Digestive 1.04 0.873 – 1.23 0.675 151 1175 exclusion phecode
575.8 Other disorders of biliary tract Digestive 0.907 0.768 – 1.07 0.248 168 1291 exclusion phecode
575.9
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of biliary tract
 Digestive 1.01 0.704 – 1.44 0.975 40 298 exclusion phecode
577 Diseases of pancreas Digestive 1.05 0.929 – 1.19 0.416 288 2617 exclusion phecode
577.1 Acute pancreatitis Digestive 0.965 0.816 – 1.14 0.676 160 1399 exclusion phecode
577.2 Chronic pancreatitis Digestive 1.05 0.806 – 1.36 0.729 64 538 exclusion phecode
577.3 Cyst and pseudocyst of pancreas Digestive 1.09 0.858 – 1.39 0.469 83 711 exclusion phecode
578 Gastrointestinal hemorrhage Digestive 1.01 0.937 – 1.1 0.728 800 3660 exclusion phecode
578.1 Hematemesis Digestive 0.946 0.737 – 1.21 0.661 69 468 exclusion phecode
578.2 Blood in stool Digestive 1.01 0.914 – 1.11 0.866 494 2687 exclusion phecode
578.8 Hemorrhage of rectum and anus Digestive 1.02 0.919 – 1.14 0.683 429 2250 exclusion phecode
578.9 Hemorrhage of gastrointestinal tract Digestive 1.08 0.932 – 1.24 0.319 215 1461 exclusion phecode
579 Other symptoms involving abdomen and pelvis Digestive 1.05 0.964 – 1.14 0.271 694 3481 exclusion phecode
579.2 Splenomegaly Digestive 1.01 0.775 – 1.31 0.955 62 654 exclusion phecode
579.8 Nonspecific abnormal findings in stool contents Digestive 1.01 0.894 – 1.14 0.877 307 1541 exclusion phecode
580 Nephritis; nephrosis; renal sclerosis Genitourinary 0.964 0.845 – 1.1 0.592 270 1671 exclusion phecode
580.1 Glomerulonephritis Genitourinary 0.996 0.773 – 1.28 0.973 71 398 exclusion phecode
580.11 Proliferative glomerulonephritis Genitourinary 0.85 0.547 – 1.32 0.468 29 133 exclusion phecode
580.12 Non-proliferative glomerulonephritis Genitourinary 0.849 0.49 – 1.47 0.56 17 92 exclusion phecode
580.13 Acute glomerulonephritis, NOS Genitourinary 0.998 0.496 – 2.01 0.995 11 59 exclusion phecode
580.14 Chronic glomerulonephritis, NOS Genitourinary 1.01 0.73 – 1.4 0.95 45 284 exclusion phecode
580.2
Nephrotic syndrome without mention of
Nephrotic syndrome without mention of glomerulonephritis
 Genitourinary 0.649 0.442 – 0.951 0.0267 34 224 exclusion phecode
580.3
Nephritis and nephropathy without mention of
Nephritis and nephropathy without mention of glomerulonephritis
 Genitourinary 0.983 0.85 – 1.14 0.819 220 1310 exclusion phecode
580.31
Nephritis and nephropathy in diseases
Nephritis and nephropathy in diseases classified elsewhere
 Genitourinary 1.03 0.856 – 1.23 0.773 139 858 exclusion phecode
580.32
Nephritis and nephropathy with pathological
Nephritis and nephropathy with pathological lesion
 Genitourinary 0.967 0.792 – 1.18 0.746 111 732 exclusion phecode
580.4 Renal sclerosis, NOS Genitourinary 0.925 0.681 – 1.26 0.62 44 374 exclusion phecode
585 Renal failure Genitourinary 0.981 0.907 – 1.06 0.625 882 3416 exclusion phecode
585.1 Acute renal failure Genitourinary 0.93 0.842 – 1.03 0.157 486 2788 exclusion phecode
585.2 Renal failure NOS Genitourinary 1.14 0.937 – 1.39 0.188 111 836 exclusion phecode
585.3 Chronic renal failure [CKD] Genitourinary 1.01 0.93 – 1.11 0.75 682 3153 exclusion phecode
585.31 Renal dialysis Genitourinary 1.14 0.922 – 1.42 0.224 95 759 exclusion phecode
585.32 End stage renal disease Genitourinary 0.945 0.794 – 1.12 0.524 153 955 exclusion phecode
585.33 Chronic Kidney Disease, Stage III Genitourinary 1.07 0.962 – 1.2 0.203 412 2290 exclusion phecode
585.34 Chronic Kidney Disease, Stage IV Genitourinary 1.03 0.856 – 1.23 0.776 138 954 exclusion phecode
585.4 Chronic kidney disease, Stage I or II Genitourinary 1.02 0.863 – 1.2 0.84 175 1202 exclusion phecode
586 Other disorders of the kidney and ureters Genitourinary 1.03 0.958 – 1.11 0.427 1011 3563 exclusion phecode
586.1 Anatomical abnormatilies of kidney and ureters Genitourinary 0.927 0.695 – 1.24 0.607 44 391 exclusion phecode
586.11 Small kidney Genitourinary 0.976 0.659 – 1.44 0.903 25 243 exclusion phecode
586.12 Vesicoureteral reflux Genitourinary 0.877 0.546 – 1.41 0.588 19 164 exclusion phecode
586.2 Cyst of kidney, acquired Genitourinary 1.02 0.876 – 1.2 0.761 184 1275 exclusion phecode
586.3 Vascular disorders of kidney/hypertrophy Genitourinary 0.898 0.563 – 1.43 0.651 24 167 exclusion phecode
586.4 Stricture/obstruction of ureter Genitourinary 0.956 0.804 – 1.14 0.606 153 1506 exclusion phecode
587 Kidney replaced by transpant Genitourinary 1.04 0.866 – 1.25 0.679 155 741 exclusion phecode
588 Disorders resulting from impaired renal function Genitourinary 0.968 0.82 – 1.14 0.7 181 1017 exclusion phecode
588.1 Renal osteodystrophy Genitourinary 0.882 0.66 – 1.18 0.398 60 243 exclusion phecode
588.2 Secondary hyperparathyroidism (of renal origin) Genitourinary 1.04 0.86 – 1.26 0.685 141 833 exclusion phecode
589 Abnormal results of function study of kidney Genitourinary 1.06 0.903 – 1.25 0.456 176 1020 exclusion phecode
590 Pyelonephritis Genitourinary 1.06 0.927 – 1.22 0.378 244 1454 exclusion phecode
591 Urinary tract infection Genitourinary 1.01 0.954 – 1.08 0.659 1876 2906 exclusion phecode
592 Cystitis and urethritis Genitourinary 1.03 0.937 – 1.13 0.562 611 2502 exclusion phecode
592.1 Cystitis Genitourinary 1.02 0.927 – 1.12 0.721 596 2451 exclusion phecode
592.11 Acute cystitis Genitourinary 0.983 0.88 – 1.1 0.756 409 1924 exclusion phecode
592.12 Chronic cystitis Genitourinary 0.894 0.656 – 1.22 0.48 48 317 exclusion phecode
592.13 Chronic interstitial cystitis Genitourinary 1.05 0.811 – 1.36 0.712 69 543 exclusion phecode
592.2 Urethritis and urethral syndrome Genitourinary 1.44 0.993 – 2.1 0.0545 30 204 exclusion phecode
593 Hematuria Genitourinary 1.01 0.935 – 1.1 0.724 797 2863 exclusion phecode
593.1 Gross hematuria Genitourinary 1.02 0.867 – 1.19 0.83 189 1194 exclusion phecode
593.2 Microscopic hematuria Genitourinary 1.07 0.922 – 1.24 0.381 230 1097 exclusion phecode
594 Urinary calculus Genitourinary 1.08 0.989 – 1.17 0.0869 638 4353 exclusion phecode
594.1 Calculus of kidney Genitourinary 1.08 0.988 – 1.18 0.0919 594 4327 exclusion phecode
594.2 Calculus of lower urinary tract Genitourinary 1.08 0.73 – 1.59 0.71 28 286 exclusion phecode
594.3 Calculus of ureter Genitourinary 1.1 0.924 – 1.3 0.29 142 1383 exclusion phecode
594.8 Renal colic Genitourinary 1.16 0.859 – 1.56 0.336 51 421 exclusion phecode
595 Hydronephrosis Genitourinary 0.987 0.839 – 1.16 0.878 164 1737 exclusion phecode
596 Other disorders of bladder Genitourinary 1.06 0.951 – 1.17 0.305 416 3124 exclusion phecode
596.1 Bladder neck obstruction Genitourinary 1.24 0.827 – 1.84 0.302 28 284 exclusion phecode
596.5 Functional disorders of bladder Genitourinary 1.01 0.889 – 1.15 0.854 273 2090 exclusion phecode
597 Other disorders of urethra and urinary tract Genitourinary 0.935 0.766 – 1.14 0.511 106 1139 exclusion phecode
597.1 Urethral stricture (not specified as infectious) Genitourinary 0.861 0.595 – 1.25 0.429 28 425 exclusion phecode
597.2 Urinary complications NEC Genitourinary 0.813 0.647 – 1.02 0.074 99 1005 exclusion phecode
597.8 Urethral hypermobility/ISD Genitourinary 1.14 0.754 – 1.72 0.533 24 280 exclusion phecode
598 Abnormal findings on examination of urine Genitourinary 1.23 0.819 – 1.86 0.314 24 162 exclusion phecode
598.4 Other cells and casts in urine Genitourinary 1.22 0.805 – 1.84 0.352 23 143 exclusion phecode
599 Other symptoms/disorders or the urinary system Genitourinary 1 0.946 – 1.06 0.925 2320 2768 exclusion phecode
599.1 Urinary obstruction Genitourinary 1.06 0.82 – 1.38 0.642 67 414 exclusion phecode
599.2 Retention of urine Genitourinary 1.04 0.951 – 1.15 0.363 588 2434 exclusion phecode
599.3 Dysuria Genitourinary 1 0.929 – 1.08 0.938 962 2631 exclusion phecode
599.4 Urinary incontinence Genitourinary 0.997 0.921 – 1.08 0.951 915 2567 exclusion phecode
599.5 Frequency of urination and polyuria Genitourinary 1.02 0.944 – 1.1 0.639 1008 2701 exclusion phecode
599.6 Oliguria and anuria Genitourinary 0.805 0.627 – 1.03 0.0892 83 458 exclusion phecode
599.7 Urethral discharge Genitourinary 1.2 0.605 – 2.37 0.606 13 71 exclusion phecode
599.8 Other symptoms involving urinary system Genitourinary 1.02 0.944 – 1.11 0.566 824 2612 exclusion phecode
599.9 Other abnormality of urination Genitourinary 1.05 0.959 – 1.16 0.272 559 2440 exclusion phecode
600 Hyperplasia of prostate Genitourinary 1.19 1.01 – 1.39 0.0368 341 521 exclusion phecode
601 Inflammatory diseases of prostate Genitourinary 1.25 0.975 – 1.61 0.0779 81 455 exclusion phecode
601.1 Prostatitis Genitourinary 1.29 0.911 – 1.81 0.153 45 223 exclusion phecode
601.11 Acute prostatitis Genitourinary 1.33 0.682 – 2.61 0.399 10 62 exclusion phecode
601.12 Chronic prostatitis Genitourinary 0.875 0.416 – 1.84 0.726 8 46 exclusion phecode
601.3 Orchitis and epididymitis Genitourinary 0.875 0.578 – 1.32 0.527 29 172 exclusion phecode
601.4 Balanoposthitis Genitourinary 1.23 0.694 – 2.2 0.473 7 60 exclusion phecode
601.8
Other inflammatory disorders of male genital
Other inflammatory disorders of male genital organs
 Genitourinary 0.867 0.474 – 1.59 0.644 10 75 exclusion phecode
602 Other disorders of prostate Genitourinary 1.08 0.72 – 1.61 0.716 31 166 exclusion phecode
602.3 Dysplasia of prostate Genitourinary 0.726 0.293 – 1.8 0.489 11 41 exclusion phecode
603 Other disorders of testis Genitourinary 1.3 0.844 – 2.01 0.232 28 172 exclusion phecode
603.1 Hydrocele Genitourinary 1.46 0.841 – 2.55 0.177 16 126 exclusion phecode
603.2 Spermatocele Genitourinary 1.04 0.536 – 2.02 0.908 18 58 exclusion phecode
604 Disorders of penis Genitourinary 1.24 0.898 – 1.71 0.193 41 257 exclusion phecode
604.1 Redundant prepuce and phimosis/BXO Genitourinary 1.35 0.616 – 2.97 0.453 7 67 exclusion phecode
604.3 Peyronie's disease Genitourinary 1.77 0.892 – 3.51 0.102 11 79 exclusion phecode
605 Erectile dysfunction [ED] Genitourinary 1.15 0.976 – 1.36 0.094 285 505 exclusion phecode
608 Other disorders of male genital organs Genitourinary 1.36 1.13 – 1.65 0.0015 150 540 exclusion phecode
609 Male infertility and abnormal spermatozoa Genitourinary 1.33 0.902 – 1.96 0.151 34 224 exclusion phecode
609.1 Infertility, male Genitourinary 1.43 0.901 – 2.28 0.128 22 152 exclusion phecode
609.11 Azoospermia and oligospermia Genitourinary 0.699 0.287 – 1.7 0.431 6 49 exclusion phecode
609.2 Abnormal spermatozoa Genitourinary 1.03 0.468 – 2.25 0.949 12 65 exclusion phecode
610 Benign mammary dysplasias Genitourinary 1.05 0.972 – 1.14 0.198 1038 1709 exclusion phecode
610.1 Cystic mastopathy Genitourinary 1.06 0.954 – 1.19 0.267 450 1500 exclusion phecode
610.2 Fibroadenosis of breast Genitourinary 1.68 0.789 – 3.57 0.179 13 50 exclusion phecode
610.4 Benign neoplasm of breast Genitourinary 1.05 0.958 – 1.14 0.321 824 1697 exclusion phecode
610.8 Other specified benign mammary dysplasias Genitourinary 1.08 0.954 – 1.23 0.217 312 1284 exclusion phecode
611 Abnormal findings on mammogram or breast exam Genitourinary 1.07 1 – 1.15 0.0371 1957 1869 exclusion phecode
611.1 Abnormal mammogram Genitourinary 1.07 1 – 1.15 0.0486 1691 1699 exclusion phecode
611.11 Mammographic microcalcification Genitourinary 1.06 0.942 – 1.19 0.345 424 1145 exclusion phecode
611.3 Lump or mass in breast Genitourinary 1.09 1.01 – 1.18 0.0273 1070 1863 exclusion phecode
612
Breast conditions, congenital or relating to
Breast conditions, congenital or relating to hormones
 Genitourinary 1.1 0.952 – 1.28 0.19 236 983 exclusion phecode
612.1 Galactorrhea Genitourinary – 36 168 exclusion phecode
612.2 Hypertrophy of breast (Gynecomastia) Genitourinary 1.05 0.874 – 1.26 0.607 165 717 exclusion phecode
612.3 Congenital anomalies of breast Genitourinary 1.21 0.74 – 1.99 0.444 30 101 exclusion phecode
613 Other nonmalignant breast conditions Genitourinary 1.07 0.994 – 1.15 0.0728 1076 3084 exclusion phecode
613.1 Inflammatory disease of breast Genitourinary – 135 861 exclusion phecode
613.5 Mastodynia Genitourinary 1.06 0.963 – 1.17 0.232 524 2359 exclusion phecode
613.7 Other signs and symptoms in breast Genitourinary 1.16 1.01 – 1.33 0.0335 255 1368 exclusion phecode
613.8 Other specified disorders of breast Genitourinary – 245 1371 exclusion phecode
613.9 Breast disorder NOS Genitourinary 1.06 0.949 – 1.18 0.303 402 2182 exclusion phecode
614 Inflammatory diseases of female pelvic organs Genitourinary 1.03 0.957 – 1.11 0.44 1039 2855 exclusion phecode
614.1
Pelvic peritoneal adhesions, female
Pelvic peritoneal adhesions, female (postoperative) (postinfection)
 Genitourinary 1.06 0.82 – 1.37 0.649 64 432 exclusion phecode
614.3 Pelvic inflammatory disease (PID) Genitourinary 0.833 0.676 – 1.03 0.086 106 610 exclusion phecode
614.31 Acute inflammatory pelvic disease Genitourinary 0.783 0.484 – 1.27 0.32 18 120 exclusion phecode
614.32 Chronic inflammatory pelvic disease Genitourinary 0.761 0.555 – 1.04 0.0896 49 233 exclusion phecode
614.33 Pelvic inflammatory disease, NOS Genitourinary 0.877 0.653 – 1.18 0.381 53 307 exclusion phecode
614.4 Inflammatory diseases of uterus, except cervix Genitourinary 0.862 0.602 – 1.23 0.414 37 202 exclusion phecode
614.5
Inflammatory disease of cervix, vagina, and
Inflammatory disease of cervix, vagina, and vulva
 Genitourinary 1.03 0.953 – 1.11 0.472 942 2830 exclusion phecode
614.51 Cervicitis and endocervicitis Genitourinary 1.05 0.818 – 1.35 0.693 72 371 exclusion phecode
614.52 Vaginitis and vulvovaginitis Genitourinary 1.03 0.951 – 1.12 0.457 822 2738 exclusion phecode
614.53 Cyst or abscess of Bartholin's gland Genitourinary 0.985 0.681 – 1.42 0.934 34 208 exclusion phecode
614.54 Abscess or ulceration of vulva Genitourinary 1.14 0.847 – 1.53 0.394 56 325 exclusion phecode
615 Endometriosis Genitourinary 0.918 0.813 – 1.04 0.164 311 1990 exclusion phecode
618 Genital prolapse Genitourinary 1.08 0.974 – 1.2 0.144 440 3043 exclusion phecode
618.1 Prolapse of vaginal walls Genitourinary 1.06 0.936 – 1.2 0.363 294 2352 exclusion phecode
618.2 Uterine/Uterovaginal prolapse Genitourinary 1.02 0.844 – 1.22 0.868 136 960 exclusion phecode
618.5 Prolapse of vaginal vault after hysterectomy Genitourinary 1.15 0.813 – 1.64 0.422 37 526 exclusion phecode
618.6 Vaginal enterocele, congenital or acquired Genitourinary 1.14 0.899 – 1.45 0.278 82 728 exclusion phecode
619 Noninflammatory female genital disorders Genitourinary 1.04 0.97 – 1.11 0.288 1410 2663 exclusion phecode
619.1
Noninflammatory disorders of ovary, fallopian
Noninflammatory disorders of ovary, fallopian tube, and broad ligament
 Genitourinary 1.02 0.888 – 1.16 0.817 250 1543 exclusion phecode
619.2 Disorders of uterus, NEC Genitourinary 0.995 0.841 – 1.18 0.954 162 821 exclusion phecode
619.3 Noninflammatory disorders of cervix Genitourinary 1.01 0.837 – 1.21 0.934 139 634 exclusion phecode
619.4 Noninflammatory disorders of vagina Genitourinary 1.05 0.958 – 1.14 0.316 672 2583 exclusion phecode
619.5 Noninflammatory disorders of vulva and perineum Genitourinary 1.06 0.939 – 1.19 0.354 333 1748 exclusion phecode
620 Dysplasia of female genital organs Genitourinary 0.988 0.79 – 1.24 0.915 89 571 exclusion phecode
620.1 Dysplasia of cervix Genitourinary 0.966 0.708 – 1.32 0.829 49 242 exclusion phecode
621 Endometrial hyperplasia Genitourinary 1.1 0.876 – 1.38 0.412 87 635 exclusion phecode
622 Polyp of female genital organs Genitourinary 1.06 0.962 – 1.18 0.224 471 2283 exclusion phecode
622.1 Polyp of corpus uteri Genitourinary 1.05 0.939 – 1.18 0.372 348 1783 exclusion phecode
622.2 Mucous polyp of cervix Genitourinary 1.16 0.976 – 1.37 0.0938 172 722 exclusion phecode
623 Hypertrophy of female genital organs Genitourinary 1.08 0.935 – 1.24 0.301 229 1329 exclusion phecode
624 Symptoms involving female genital tract Genitourinary 1 0.893 – 1.12 0.973 373 1515 exclusion phecode
624.1 Dystrophy of female genital tract Genitourinary 0.963 0.72 – 1.29 0.798 53 273 exclusion phecode
624.2 Atrophy of female genital tract Genitourinary 1.07 0.631 – 1.8 0.81 20 82 exclusion phecode
624.9 stress incontinence, female Genitourinary 1.04 0.935 – 1.15 0.494 452 1990 exclusion phecode
625
Pain and other symptoms associated with female
Pain and other symptoms associated with female genital organs
 Genitourinary 0.988 0.924 – 1.06 0.726 1556 2198 exclusion phecode
625.1 Dyspareunia Genitourinary 0.966 0.855 – 1.09 0.577 323 1466 exclusion phecode
626
Disorders of menstruation and other abnormal
Disorders of menstruation and other abnormal bleeding from female genital tract
 Genitourinary 1.02 0.947 – 1.1 0.606 1510 1651 exclusion phecode
626.1 Irregular menstrual cycle/bleeding Genitourinary 1.03 0.954 – 1.12 0.424 1208 1519 exclusion phecode
626.11 Absent or infrequent menstruation Genitourinary 1.18 1.02 – 1.36 0.0275 269 829 exclusion phecode
626.12 Excessive or frequent menstruation Genitourinary 1.05 0.949 – 1.17 0.334 567 1203 exclusion phecode
626.13 Irregular menstrual cycle Genitourinary 1.06 0.959 – 1.18 0.241 574 1260 exclusion phecode
626.14 Irregular menstrual bleeding Genitourinary 1.06 0.921 – 1.21 0.427 265 879 exclusion phecode
626.15 Infertility, female, associated with anovulation Genitourinary 1.14 0.929 – 1.4 0.208 120 432 exclusion phecode
626.2 Dysmenorrhea Genitourinary 1.07 0.931 – 1.22 0.359 313 958 exclusion phecode
626.4 Premenstrual tension syndromes Genitourinary 0.886 0.708 – 1.11 0.292 112 365 exclusion phecode
626.8 Infertility, female Genitourinary 1.06 0.909 – 1.24 0.443 216 658 exclusion phecode
627 Menopausal and postmenopausal disorders Genitourinary 0.982 0.913 – 1.06 0.632 1533 1565 exclusion phecode
627.1 Postmenopausal bleeding Genitourinary 1.02 0.909 – 1.14 0.737 396 1186 exclusion phecode
627.2 Symptomatic menopause Genitourinary 0.976 0.9 – 1.06 0.56 1097 1488 exclusion phecode
627.21 Symptomatic artificial menopause Genitourinary 0.905 0.638 – 1.28 0.575 40 169 exclusion phecode
627.22
Need for Hormone replacement therapy
Need for Hormone replacement therapy (postmenopausal)
 Genitourinary 0.742 0.608 – 0.906 0.00341 156 428 exclusion phecode
627.3 Postmenopausal atrophic vaginitis Genitourinary 0.996 0.883 – 1.12 0.947 375 1118 exclusion phecode
627.4 Premenopausal menorrhagia Genitourinary 1.16 0.917 – 1.46 0.219 105 368 exclusion phecode
627.5 Premature menopause and other ovarian failure Genitourinary 1.3 1.01 – 1.66 0.0384 81 330 exclusion phecode
628 Ovarian cyst Genitourinary 1.02 0.912 – 1.13 0.782 487 1423 exclusion phecode
634 Miscarriage; stillbirth Pregnancy Complications 1 0.866 – 1.16 0.964 216 1096 exclusion phecode
634.1 Missed abortion/Hydatidiform mole Pregnancy Complications 1.16 0.921 – 1.47 0.204 81 385 exclusion phecode
634.3 Ectopic pregnancy Pregnancy Complications 1.12 0.697 – 1.8 0.64 19 138 exclusion phecode
635
Hemorrhage during pregnancy; childbirth and
Hemorrhage during pregnancy; childbirth and postpartum
 Pregnancy Complications 1.04 0.869 – 1.24 0.684 150 666 exclusion phecode
635.2
Antepartum hemorrhage, abruptio placentae, and
Antepartum hemorrhage, abruptio placentae, and placenta previa
 Pregnancy Complications 0.95 0.766 – 1.18 0.643 105 462 exclusion phecode
635.3 Placenta previa and abruptio placenta Pregnancy Complications 1.08 0.838 – 1.39 0.55 72 325 exclusion phecode
636
Early or threatened labor; hemorrhage in early
Early or threatened labor; hemorrhage in early pregnancy
 Pregnancy Complications 1.12 0.976 – 1.28 0.108 277 1023 exclusion phecode
636.1 Threatened premature labor Pregnancy Complications 1.17 0.94 – 1.47 0.157 100 451 exclusion phecode
636.2 Early onset of delivery Pregnancy Complications 1.09 0.848 – 1.41 0.492 74 369 exclusion phecode
636.3 Hemorrhage in early pregnancy Pregnancy Complications 0.876 0.712 – 1.08 0.212 112 565 exclusion phecode
636.8 Cervical incompetence Pregnancy Complications 1.02 0.587 – 1.76 0.951 16 97 exclusion phecode
637
Short gestation; low birth weight; and fetal
Short gestation; low birth weight; and fetal growth retardation
 Pregnancy Complications 1.1 0.622 – 1.94 0.747 12 80 exclusion phecode
642
Hypertension complicating pregnancy
Hypertension complicating pregnancy, childbirth, and the puerperium
 Pregnancy Complications 1.07 0.884 – 1.28 0.503 130 870 exclusion phecode
642.1 Preeclampsia and eclampsia Pregnancy Complications 0.959 0.744 – 1.24 0.747 72 474 exclusion phecode
643 Excessive vomiting in pregnancy Pregnancy Complications 0.925 0.703 – 1.22 0.58 61 350 exclusion phecode
643.1 Hyperemesis gravidarum Pregnancy Complications 0.863 0.582 – 1.28 0.462 33 175 exclusion phecode
644 Anemia during pregnancy Pregnancy Complications 1.12 0.844 – 1.49 0.427 53 303 exclusion phecode
646 Other complications of pregnancy NEC Pregnancy Complications 1 0.858 – 1.17 0.977 202 807 exclusion phecode
647
Infectious and parasitic complications
Infectious and parasitic complications affecting pregnancy
 Pregnancy Complications 1.25 0.947 – 1.66 0.114 61 323 exclusion phecode
647.1
Infections of genitourinary tract during
Infections of genitourinary tract during pregnancy
 Pregnancy Complications 0.831 0.622 – 1.11 0.211 49 284 exclusion phecode
647.3 Major puerperal infection Pregnancy Complications 0.924 0.521 – 1.64 0.787 19 89 exclusion phecode
649
Other conditions or status of the mother
Other conditions or status of the mother complicating pregnancy, childbirth, or the puerperium
 Pregnancy Complications 0.965 0.848 – 1.1 0.583 317 1031 exclusion phecode
649.1
Diabetes or abnormal glucose tolerance
Diabetes or abnormal glucose tolerance complicating pregnancy
 Pregnancy Complications 0.889 0.75 – 1.05 0.178 170 879 exclusion phecode
653
Problems associated with amniotic cavity and
Problems associated with amniotic cavity and membranes
 Pregnancy Complications 1.04 0.872 – 1.25 0.649 144 739 exclusion phecode
654.1
Abnormality of organs and soft tissues of
Abnormality of organs and soft tissues of pelvis complicating pregnancy, childbirth, or the puerperium
 Pregnancy Complications 0.968 0.714 – 1.31 0.833 50 259 exclusion phecode
654.2 Rhesus isoimmunization in pregnancy Pregnancy Complications 0.993 0.744 – 1.32 0.959 53 254 exclusion phecode
655
Known or suspected fetal abnormality affecting
Known or suspected fetal abnormality affecting management of mother
 Pregnancy Complications 1.08 0.965 – 1.21 0.182 435 1364 exclusion phecode
655.1 Abnormality in fetal heart rate or rhythm Pregnancy Complications 1.09 0.916 – 1.3 0.326 168 666 exclusion phecode
656 Other perinatal conditions of fetus or newborn Pregnancy Complications 1.02 0.873 – 1.2 0.774 203 830 exclusion phecode
656.2 Respiratory conditions of fetus and newborn Pregnancy Complications 1.8 0.821 – 3.95 0.142 10 64 exclusion phecode
669 Complications of labor and delivery NEC Pregnancy Complications 0.998 0.856 – 1.16 0.98 203 906 exclusion phecode
671
Venous/cerebrovascular complications embolism
Venous/cerebrovascular complications embolism in pregnancy and the puerperium
 Pregnancy Complications 0.923 0.695 – 1.23 0.581 61 335 exclusion phecode
674 Other complications of the puerperium NEC Pregnancy Complications 1.16 0.831 – 1.62 0.381 34 220 exclusion phecode
676
Other disorders of the breast associated with
Other disorders of the breast associated with childbirth and disorders of lactation
 Pregnancy Complications 1.18 0.88 – 1.57 0.273 55 266 exclusion phecode
681 Superficial cellulitis and abscess Dermatologic 1.04 0.974 – 1.12 0.225 1060 3818 exclusion phecode
681.1 Cellulitis and abscess of fingers/toes Dermatologic 0.951 0.825 – 1.1 0.484 244 1368 exclusion phecode
681.2 Cellulitis and abscess of face/neck Dermatologic 0.999 0.848 – 1.18 0.992 166 1022 exclusion phecode
681.3 Cellulitis and abscess of arm/hand Dermatologic 0.996 0.888 – 1.12 0.94 357 2096 exclusion phecode
681.5 Cellulitis and abscess of leg, except foot Dermatologic 0.992 0.884 – 1.11 0.894 350 2098 exclusion phecode
681.6 Cellulitis and abscess of foot, toe Dermatologic 1.04 0.918 – 1.18 0.533 296 1734 exclusion phecode
681.7 Cellulitis and abscess of trunk Dermatologic 1.09 0.935 – 1.28 0.262 175 1614 exclusion phecode
686
Other local infections of skin and subcutaneous
Other local infections of skin and subcutaneous tissue
 Dermatologic 0.96 0.86 – 1.07 0.466 371 2243 exclusion phecode
686.1 Carbuncle and furuncle Dermatologic 1.32 1.07 – 1.64 0.00975 106 715 exclusion phecode
686.2 Impetigo Dermatologic 0.951 0.748 – 1.21 0.679 87 519 exclusion phecode
686.3 Pilonidal cyst Dermatologic 0.967 0.622 – 1.5 0.882 25 171 exclusion phecode
686.4 Pyogenic granuloma Dermatologic 1.03 0.693 – 1.54 0.87 34 194 exclusion phecode
686.5 Pyoderma Dermatologic 0.865 0.478 – 1.57 0.632 13 71 exclusion phecode
687 Symptoms affecting skin Dermatologic 0.914 0.814 – 1.03 0.13 392 1607 exclusion phecode
687.1 Rash and other nonspecific skin eruption Dermatologic 1.05 0.983 – 1.12 0.15 1618 2787 exclusion phecode
687.3 Changes in skin texture Dermatologic 1.01 0.791 – 1.29 0.926 82 460 exclusion phecode
687.4 Disturbance of skin sensation Dermatologic 1.02 0.954 – 1.1 0.53 1205 2767 exclusion phecode
689 Disorder of skin and subcutaneous tissue NOS Dermatologic 0.958 0.904 – 1.02 0.15 2075 3152 exclusion phecode
690 Erythematosquamous dermatosis Dermatologic 1.01 0.94 – 1.08 0.835 1327 2824 exclusion phecode
690.1 Seborrheic dermatitis Dermatologic 1.01 0.941 – 1.08 0.824 1325 2824 exclusion phecode
691 Congenital anomalies of skin Dermatologic 1.05 0.846 – 1.31 0.649 103 552 exclusion phecode
691.3 Congenital pigmentary anomalies of skin Dermatologic 1.2 0.579 – 2.48 0.625 9 59 exclusion phecode
694 Dyschromia and Vitiligo Dermatologic 0.952 0.862 – 1.05 0.331 523 1831 exclusion phecode
694.1 Vitiligo Dermatologic 0.799 0.521 – 1.23 0.304 25 152 exclusion phecode
694.2 Other dyschromia Dermatologic 0.961 0.867 – 1.06 0.445 493 1673 exclusion phecode
694.3 Vascular disorders of skin Dermatologic 1.28 0.615 – 2.66 0.509 14 77 exclusion phecode
695 Erythematous conditions Dermatologic 1.01 0.937 – 1.1 0.739 861 2821 exclusion phecode
695.1 Toxic erythema Dermatologic 1.34 0.787 – 2.28 0.281 14 82 exclusion phecode
695.2 Bullous dermatoses Dermatologic 1.19 0.686 – 2.05 0.54 17 78 exclusion phecode
695.3 Rosacea Dermatologic 1 0.904 – 1.11 0.982 474 1862 exclusion phecode
695.4 Lupus (localized and systemic) Dermatologic 1.04 0.87 – 1.24 0.672 136 758 exclusion phecode
695.41 Cutaneous lupus erythematosus Dermatologic 1.07 0.804 – 1.42 0.651 60 276 exclusion phecode
695.42 Systemic lupus erythematosus Dermatologic 1.07 0.89 – 1.28 0.486 128 723 exclusion phecode
695.7 Prurigo and Lichen Dermatologic 1 0.825 – 1.22 0.977 112 649 exclusion phecode
695.8 Other specified erythematous conditions Dermatologic 1.06 0.889 – 1.25 0.539 158 853 exclusion phecode
695.81 Erythema nodosum Dermatologic 0.94 0.5 – 1.77 0.849 14 51 exclusion phecode
695.9 Unspecified erythematous condition Dermatologic 1.14 0.93 – 1.41 0.203 109 648 exclusion phecode
696 Psoriasis and related disorders Dermatologic 1.04 0.909 – 1.2 0.549 263 1262 exclusion phecode
696.3 Pityriasis Dermatologic 1.13 0.754 – 1.69 0.555 33 91 exclusion phecode
696.4 Psoriasis Dermatologic 1.03 0.886 – 1.19 0.733 234 1183 exclusion phecode
696.41 Psoriasis vulgaris Dermatologic 1.02 0.879 – 1.19 0.781 224 1085 exclusion phecode
696.42 Psoriatic arthropathy Dermatologic 1.26 0.892 – 1.79 0.189 43 214 exclusion phecode
697 Sarcoidosis Dermatologic 0.976 0.707 – 1.35 0.881 47 313 exclusion phecode
698 Pruritus and related conditions Dermatologic 0.951 0.865 – 1.05 0.303 533 3004 exclusion phecode
700 Corns and callosities Dermatologic 0.951 0.833 – 1.09 0.454 305 1317 exclusion phecode
701
Other hypertrophic and atrophic conditions of
Other hypertrophic and atrophic conditions of skin
 Dermatologic 1.03 0.964 – 1.09 0.422 1549 3499 exclusion phecode
701.1 Keratoderma, acquired Dermatologic 1.01 0.835 – 1.23 0.895 140 661 exclusion phecode
701.2 Scar conditions and fibrosis of skin Dermatologic 1.04 0.932 – 1.16 0.487 390 2225 exclusion phecode
701.3 Circumscribed scleroderma Dermatologic 0.999 0.833 – 1.2 0.989 138 765 exclusion phecode
701.4 Keloid scar Dermatologic 0.994 0.812 – 1.22 0.955 117 615 exclusion phecode
701.5 Abnormal granulation tissue Dermatologic 1.13 0.836 – 1.53 0.424 47 397 exclusion phecode
702
Degenerative skin conditions and other
Degenerative skin conditions and other dermatoses
 Dermatologic 1.03 0.965 – 1.1 0.354 1752 2430 exclusion phecode
702.1 Actinic keratosis Dermatologic 1.01 0.936 – 1.09 0.791 1061 2328 exclusion phecode
702.2 Seborrheic keratosis Dermatologic 1.02 0.956 – 1.1 0.501 1440 2916 exclusion phecode
702.4 Degenerative skin disorders Dermatologic 0.939 0.54 – 1.63 0.822 20 112 exclusion phecode
703 Diseases of nail, NOS Dermatologic 1.05 0.94 – 1.18 0.373 379 1811 exclusion phecode
703.1 Ingrowing nail Dermatologic 1.12 0.958 – 1.32 0.153 176 1095 exclusion phecode
704 Diseases of hair and hair follicles Dermatologic 1.04 0.963 – 1.13 0.302 760 3432 exclusion phecode
704.1 Alopecia Dermatologic 1.1 0.991 – 1.23 0.0724 421 1969 exclusion phecode
704.11 Alopecia Areata Dermatologic 1.03 0.62 – 1.71 0.908 18 96 exclusion phecode
704.12 Telogen effluvium Dermatologic 0.803 0.474 – 1.36 0.417 20 82 exclusion phecode
704.2 Hirsutism Dermatologic 1.07 0.806 – 1.43 0.633 65 398 exclusion phecode
704.8
Other specified diseases of hair and hair
Other specified diseases of hair and hair follicles
 Dermatologic 0.998 0.885 – 1.13 0.976 355 1866 exclusion phecode
705 Disorders of sweat glands Dermatologic 0.888 0.718 – 1.1 0.273 96 667 exclusion phecode
705.1 Dyshidrosis Dermatologic 1.05 0.724 – 1.52 0.8 34 179 exclusion phecode
705.3 Hidradenitis Dermatologic 0.85 0.556 – 1.3 0.456 22 241 exclusion phecode
705.8 Hyperhidrosis Dermatologic 1.08 0.935 – 1.24 0.306 241 1141 exclusion phecode
706 Diseases of sebaceous glands Dermatologic 0.984 0.924 – 1.05 0.617 1435 3607 exclusion phecode
706.1 Acne Dermatologic 0.959 0.878 – 1.05 0.358 664 2360 exclusion phecode
706.2 Sebaceous cyst Dermatologic 0.973 0.893 – 1.06 0.524 691 2758 exclusion phecode
706.3 Seborrhea Dermatologic 0.881 0.492 – 1.58 0.671 13 63 exclusion phecode
706.8 Other specified diseases of sebaceous glands Dermatologic 1.04 0.93 – 1.17 0.469 385 1653 exclusion phecode
707 Chronic ulcer of skin Dermatologic 0.921 0.824 – 1.03 0.143 365 3043 exclusion phecode
707.1 Decubitus ulcer Dermatologic 0.819 0.66 – 1.02 0.0681 93 820 exclusion phecode
707.2 Chronic ulcer of leg or foot Dermatologic 0.955 0.804 – 1.13 0.598 149 1052 exclusion phecode
707.3 Chronic ulcer of unspecified site Dermatologic 0.995 0.863 – 1.15 0.944 218 1990 exclusion phecode
709 Diffuse diseases of connective tissue Dermatologic 0.994 0.883 – 1.12 0.916 345 1607 exclusion phecode
709.2 Sicca syndrome Dermatologic 1.12 0.906 – 1.37 0.301 119 540 exclusion phecode
709.3 Systemic sclerosis Dermatologic 1.08 0.768 – 1.51 0.673 41 240 exclusion phecode
709.5 Dermatomyositis Dermatologic 1.25 0.757 – 2.05 0.387 21 100 exclusion phecode
709.6
Other specified diffuse diseases of connective
Other specified diffuse diseases of connective tissue
 Dermatologic 0.819 0.493 – 1.36 0.441 20 81 exclusion phecode
709.7 Unspecified diffuse connective tissue disease Dermatologic 0.978 0.846 – 1.13 0.758 230 1048 exclusion phecode
710
Osteomyelitis, periostitis, and other
Osteomyelitis, periostitis, and other infections involving bone
 Musculoskeletal 1.1 0.904 – 1.33 0.353 124 1034 exclusion phecode
710.1 Osteomyelitis Musculoskeletal 1.09 0.89 – 1.32 0.417 116 985 exclusion phecode
710.11 Acute osteomyelitis Musculoskeletal 0.895 0.659 – 1.22 0.48 45 497 exclusion phecode
710.12 Chronic osteomyelitis Musculoskeletal 1.14 0.837 – 1.55 0.405 53 427 exclusion phecode
710.19 Unspecified osteomyelitis Musculoskeletal 1.08 0.886 – 1.33 0.431 110 927 exclusion phecode
711 Arthropathy associated with infections Musculoskeletal 0.903 0.679 – 1.2 0.481 55 339 exclusion phecode
711.1 Pyogenic arthritis Musculoskeletal 0.901 0.641 – 1.27 0.547 35 211 exclusion phecode
712 Infective connective tissue disorders Musculoskeletal 1.44 0.888 – 2.35 0.139 15 151 exclusion phecode
713
Arthropathy associated with other disorders
Arthropathy associated with other disorders classified elsewhere
 Musculoskeletal 1.14 0.844 – 1.54 0.393 52 361 exclusion phecode
713.5
Arthropathy associated with neurological
Arthropathy associated with neurological disorders
 Musculoskeletal 1.02 0.688 – 1.5 0.938 31 227 exclusion phecode
714
Rheumatoid arthritis and other inflammatory
Rheumatoid arthritis and other inflammatory polyarthropathies
 Musculoskeletal 1.04 0.925 – 1.16 0.531 378 1955 exclusion phecode
714.1 Rheumatoid arthritis Musculoskeletal 1.04 0.92 – 1.19 0.502 305 1657 exclusion phecode
714.2 Juvenile rheumatoid arthritis Musculoskeletal 0.57 0.262 – 1.24 0.157 7 74 exclusion phecode
715 Other inflammatory spondylopathies Musculoskeletal 0.973 0.837 – 1.13 0.721 225 1170 exclusion phecode
715.1 Sacroiliitis NEC Musculoskeletal 0.971 0.717 – 1.32 0.849 57 292 exclusion phecode
715.2 Ankylosing spondylitis Musculoskeletal 1.2 0.775 – 1.85 0.419 26 196 exclusion phecode
716 Other arthropathies Musculoskeletal 0.959 0.901 – 1.02 0.186 2131 2897 exclusion phecode
716.1 Unspecified polyarthropathy or polyarthritis Musculoskeletal 1.38 0.949 – 2.01 0.0921 39 217 exclusion phecode
716.2 Unspecified monoarthritis Musculoskeletal 1.14 0.754 – 1.73 0.532 27 124 exclusion phecode
716.9 Arthropathy NOS Musculoskeletal 0.957 0.899 – 1.02 0.165 2119 2896 exclusion phecode
717 Polymyalgia Rheumatica Musculoskeletal 1.07 0.818 – 1.41 0.607 64 333 exclusion phecode
720 Spinal stenosis Musculoskeletal 1.02 0.93 – 1.12 0.663 617 2581 exclusion phecode
720.1 Spinal stenosis of lumbar region Musculoskeletal 0.989 0.888 – 1.1 0.837 449 2100 exclusion phecode
721 Spondylosis and allied disorders Musculoskeletal 1.01 0.935 – 1.08 0.876 1092 3020 exclusion phecode
721.1 Spondylosis without myelopathy Musculoskeletal 1.01 0.937 – 1.09 0.797 1048 3002 exclusion phecode
721.2 Spondylosis with myelopathy Musculoskeletal 1.05 0.877 – 1.26 0.591 127 776 exclusion phecode
721.8 Other allied disorders of spine Musculoskeletal 1.06 0.758 – 1.48 0.74 50 269 exclusion phecode
722 Intervertebral disc disorders Musculoskeletal 1.01 0.938 – 1.09 0.814 1097 3148 exclusion phecode
722.1 Displacement of intervertebral disc Musculoskeletal 1.02 0.935 – 1.12 0.638 644 2932 exclusion phecode
722.3 Schmorl's nodes Musculoskeletal 0.868 0.407 – 1.85 0.715 18 66 exclusion phecode
722.6 Degeneration of intervertebral disc Musculoskeletal 0.993 0.912 – 1.08 0.874 734 2879 exclusion phecode
722.7 Intervertebral disc disorder with myelopathy Musculoskeletal 1.1 0.863 – 1.4 0.447 72 477 exclusion phecode
722.8 Postlaminectomy syndrome Musculoskeletal 1.29 0.991 – 1.68 0.0585 61 370 exclusion phecode
722.9 Other and unspecified disc disorder Musculoskeletal 1.02 0.908 – 1.15 0.709 326 1894 exclusion phecode
723 Other disorders of cervical region Musculoskeletal 1.06 0.903 – 1.24 0.475 183 964 exclusion phecode
723.1 Torticollis Musculoskeletal 0.921 0.663 – 1.28 0.621 49 241 exclusion phecode
724 Other and unspecified disorders of back Musculoskeletal 1.01 0.936 – 1.09 0.778 908 3091 exclusion phecode
724.1 Disorders of sacrum Musculoskeletal 0.966 0.881 – 1.06 0.467 605 2495 exclusion phecode
724.2 Disorders of coccyx Musculoskeletal 1.04 0.834 – 1.28 0.753 106 468 exclusion phecode
724.8 Other symptoms referable to back Musculoskeletal 1.06 0.899 – 1.24 0.497 181 882 exclusion phecode
724.9 Other unspecified back disorders Musculoskeletal 1.02 0.888 – 1.18 0.741 229 1285 exclusion phecode
726 Peripheral enthesopathies and allied syndromes Musculoskeletal 1.01 0.948 – 1.08 0.745 2202 2088 exclusion phecode
726.1 Enthesopathy Musculoskeletal 1 0.935 – 1.07 0.958 1748 2077 exclusion phecode
726.2 Synoviopathy Musculoskeletal 0.941 0.804 – 1.1 0.452 214 745 exclusion phecode
726.3 Bursitis Musculoskeletal 0.976 0.871 – 1.09 0.678 440 1333 exclusion phecode
726.4 Calcaneal spur; Exostosis NOS Musculoskeletal 0.987 0.856 – 1.14 0.856 280 960 exclusion phecode
727 Other disorders of synovium, tendon, and bursa Musculoskeletal 1.01 0.939 – 1.08 0.849 1629 2075 exclusion phecode
727.1 Synovitis and tenosynovitis Musculoskeletal 1.02 0.934 – 1.12 0.624 734 1874 exclusion phecode
727.2 Bursitis disorders Musculoskeletal 1.03 0.792 – 1.33 0.85 109 355 exclusion phecode
727.4 Ganglion and cyst of synovium, tendon, and bursa Musculoskeletal 0.943 0.836 – 1.06 0.334 396 1113 exclusion phecode
727.5 Rupture of synovium Musculoskeletal 0.997 0.803 – 1.24 0.977 130 387 exclusion phecode
727.6 Rupture of tendon, nontraumatic Musculoskeletal 1.01 0.909 – 1.12 0.835 520 1413 exclusion phecode
727.7 Contracture of tendon (sheath) Musculoskeletal 0.914 0.729 – 1.15 0.433 115 431 exclusion phecode
727.8 Plica syndrome Musculoskeletal 1.23 0.696 – 2.17 0.478 13 60 exclusion phecode
728 Disorders of muscle, ligament, and fascia Musculoskeletal 0.998 0.917 – 1.09 0.965 844 2013 exclusion phecode
728.1 Muscular calcification and ossification Musculoskeletal 0.516 0.221 – 1.2 0.126 9 52 exclusion phecode
728.2 Laxity of ligament or hypermobility syndrome Musculoskeletal 0.993 0.735 – 1.34 0.962 47 208 exclusion phecode
728.7 Fasciitis Musculoskeletal 1.03 0.942 – 1.13 0.487 694 1781 exclusion phecode
728.71
Contracture of palmar fascia [Dupuytren's
Contracture of palmar fascia [Dupuytren's disease]
 Musculoskeletal 1.02 0.802 – 1.28 0.9 108 312 exclusion phecode
729 Other disorders of soft tissues Musculoskeletal 0.986 0.897 – 1.09 0.779 624 1895 exclusion phecode
729.1 Rheumatism, unspecified and fibrositis Musculoskeletal 1.32 0.82 – 2.14 0.251 21 70 exclusion phecode
729.3 Panniculitis Musculoskeletal 0.993 0.595 – 1.66 0.979 20 90 exclusion phecode
729.7 Nontraumatic compartment syndrome Musculoskeletal 1.09 0.434 – 2.73 0.857 8 41 exclusion phecode
731
Osteitis deformans and osteopathies associated
Osteitis deformans and osteopathies associated with other disorders classified elsewhere
 Musculoskeletal 0.862 0.522 – 1.42 0.562 22 184 exclusion phecode
732 Osteochondropathies Musculoskeletal 0.922 0.69 – 1.23 0.581 47 298 exclusion phecode
732.1 Juvenile osteochondrosis Musculoskeletal 1.12 0.77 – 1.64 0.542 29 166 exclusion phecode
732.7 Osteochondritis dissecans Musculoskeletal 1 0.595 – 1.68 0.999 13 65 exclusion phecode
733 Other disorders of bone and cartilage Musculoskeletal 1.02 0.943 – 1.1 0.657 1270 2417 exclusion phecode
733.2 Cyst of bone Musculoskeletal 0.82 0.548 – 1.23 0.335 35 163 exclusion phecode
733.4 Aseptic necrosis of bone Musculoskeletal 1.05 0.813 – 1.35 0.723 78 399 exclusion phecode
733.6 Costochondritis Musculoskeletal 1.07 0.829 – 1.39 0.588 88 379 exclusion phecode
733.8 Malunion and nonunion of fracture Musculoskeletal 1.07 0.865 – 1.33 0.524 109 624 exclusion phecode
733.9 Chondromalacia Musculoskeletal 0.801 0.459 – 1.4 0.435 13 65 exclusion phecode
735 Acquired foot deformities Musculoskeletal 1.05 0.968 – 1.13 0.247 805 3216 exclusion phecode
735.1 Flat foot Musculoskeletal 0.913 0.749 – 1.11 0.37 116 727 exclusion phecode
735.2 Acquired toe deformities Musculoskeletal 0.986 0.875 – 1.11 0.822 357 1527 exclusion phecode
735.21 Hammer toe (acquired) Musculoskeletal 0.962 0.827 – 1.12 0.61 225 988 exclusion phecode
735.23 Hallux rigidus Musculoskeletal 0.984 0.802 – 1.21 0.879 118 526 exclusion phecode
735.3 Hallux valgus (Bunion) Musculoskeletal 1.02 0.92 – 1.14 0.682 448 1809 exclusion phecode
736 Other acquired deformities of limbs Musculoskeletal 1.02 0.933 – 1.12 0.618 557 2792 exclusion phecode
736.1 Acquired deformities of forearm Musculoskeletal 0.934 0.538 – 1.62 0.809 15 84 exclusion phecode
736.2 Acquired deformities of finger Musculoskeletal 0.804 0.589 – 1.1 0.17 52 189 exclusion phecode
736.3 Acquired deformities of hip Musculoskeletal 0.862 0.405 – 1.84 0.701 9 45 exclusion phecode
736.4 Genu valgum or varum (acquired) Musculoskeletal 1.25 0.941 – 1.67 0.122 61 348 exclusion phecode
736.5 Acquired deformities of knee Musculoskeletal 1.48 0.999 – 2.18 0.0509 33 236 exclusion phecode
736.6 Unequal leg length (acquired) Musculoskeletal 1.12 0.869 – 1.44 0.381 83 369 exclusion phecode
737 Curvature of spine Musculoskeletal 1.04 0.918 – 1.18 0.537 303 1686 exclusion phecode
737.1 Kyphosis (acquired) Musculoskeletal 1.26 0.97 – 1.63 0.0842 67 473 exclusion phecode
737.2 Lordosis (acquired) Musculoskeletal 1.96 0.612 – 6.26 0.258 7 61 exclusion phecode
737.3 Kyphoscoliosis and scoliosis Musculoskeletal 1.03 0.896 – 1.18 0.699 248 1316 exclusion phecode
738 Other acquired musculoskeletal deformity Musculoskeletal 0.943 0.844 – 1.05 0.303 370 2360 exclusion phecode
738.4 Acquired spondylolisthesis Musculoskeletal 0.896 0.766 – 1.05 0.171 186 1093 exclusion phecode
739 Contracture of joint Musculoskeletal 1.04 0.846 – 1.27 0.736 115 617 exclusion phecode
740 Osteoarthrosis Musculoskeletal 0.982 0.923 – 1.05 0.573 2489 2692 exclusion phecode
740.1 Osteoarthritis; localized Musculoskeletal 0.981 0.91 – 1.06 0.609 1449 2424 exclusion phecode
740.11 Osteoarthrosis, localized, primary Musculoskeletal 0.972 0.899 – 1.05 0.464 1325 2335 exclusion phecode
740.12 Osteoarthrosis, localized, secondary Musculoskeletal 0.817 0.668 – 1 0.05 118 566 exclusion phecode
740.2 Osteoarthrosis, generalized Musculoskeletal 0.88 0.777 – 0.996 0.0432 445 1176 exclusion phecode
740.3
Osteoarthrosis involving more than one site
Osteoarthrosis involving more than one site, but not specified as generalized
 Musculoskeletal 0.8 0.629 – 1.02 0.0682 100 381 exclusion phecode
740.9 Osteoarthrosis NOS Musculoskeletal 0.987 0.926 – 1.05 0.677 2392 2681 exclusion phecode
741 Symptoms and disorders of the joints Musculoskeletal 0.983 0.923 – 1.05 0.592 1625 3231 exclusion phecode
741.1 Ankylosis of joint Musculoskeletal 0.98 0.682 – 1.41 0.915 26 168 exclusion phecode
741.2 Stiffness of joint Musculoskeletal 0.954 0.833 – 1.09 0.498 258 1286 exclusion phecode
741.3 Difficulty in walking Musculoskeletal 1.03 0.923 – 1.14 0.622 411 1963 exclusion phecode
741.4 Joint effusions Musculoskeletal 0.968 0.881 – 1.06 0.501 576 2296 exclusion phecode
741.5 Hemarthrosis Musculoskeletal 0.814 0.458 – 1.45 0.481 18 95 exclusion phecode
741.6 Villonodular synovitis Musculoskeletal 0.596 0.347 – 1.03 0.0616 18 60 exclusion phecode
742 Derangement of joint, non-traumatic Musculoskeletal 0.964 0.892 – 1.04 0.346 857 3098 exclusion phecode
742.1 Loose body in joint Musculoskeletal 0.972 0.624 – 1.51 0.899 21 116 exclusion phecode
742.2
Pathological, developmental or recurrent
Pathological, developmental or recurrent dislocation
 Musculoskeletal 0.929 0.632 – 1.37 0.707 25 180 exclusion phecode
742.8 Articular cartilage disorder Musculoskeletal 1.18 0.815 – 1.7 0.385 34 200 exclusion phecode
742.9 Other derangement of joint Musculoskeletal 0.958 0.886 – 1.04 0.288 823 3067 exclusion phecode
743
Osteoporosis, osteopenia and pathological
Osteoporosis, osteopenia and pathological fracture
 Musculoskeletal 0.997 0.933 – 1.06 0.92 2051 3098 exclusion phecode
743.1 Osteoporosis Musculoskeletal 1.01 0.923 – 1.11 0.817 984 1904 exclusion phecode
743.11 Osteoporosis NOS Musculoskeletal 1.01 0.922 – 1.11 0.835 973 1895 exclusion phecode
743.12 Senile osteoporosis Musculoskeletal 0.983 0.846 – 1.14 0.822 305 555 exclusion phecode
743.13 Other specified osteoporosis Musculoskeletal 0.854 0.671 – 1.09 0.2 102 315 exclusion phecode
743.2 Pathologic fracture Musculoskeletal 0.958 0.827 – 1.11 0.567 253 898 exclusion phecode
743.21 Pathologic fracture of vertebrae Musculoskeletal 0.965 0.758 – 1.23 0.772 97 349 exclusion phecode
743.22 Pathologic fracture of femur Musculoskeletal 0.633 0.378 – 1.06 0.082 31 114 exclusion phecode
743.4 Stress fracture Musculoskeletal 0.97 0.788 – 1.19 0.772 119 483 exclusion phecode
743.9
Osteopenia or other disorder of bone and
Osteopenia or other disorder of bone and cartilage
 Musculoskeletal 1 0.934 – 1.07 0.977 1705 2966 exclusion phecode
745 Pain in joint Musculoskeletal 1.04 0.975 – 1.1 0.251 3658 1574 exclusion phecode
747 Cardiac and circulatory congenital anomalies Congenital Anomalies 0.926 0.826 – 1.04 0.192 347 2270 exclusion phecode
747.1 Cardiac congenital anomalies Congenital Anomalies 0.931 0.819 – 1.06 0.277 282 1740 exclusion phecode
747.11 Cardiac shunt/ heart septal defect Congenital Anomalies 1 0.825 – 1.22 0.964 114 711 exclusion phecode
747.12 Valvular heart disease/ heart chambers Congenital Anomalies 0.866 0.703 – 1.07 0.176 115 648 exclusion phecode
747.13 Congenital anomalies of great vessels Congenital Anomalies 0.84 0.632 – 1.12 0.233 59 366 exclusion phecode
747.2
Congenital anomalies of peripheral vascular
Congenital anomalies of peripheral vascular system
 Congenital Anomalies 0.89 0.68 – 1.16 0.395 64 529 exclusion phecode
748 Anomalies of respiratory system, congenital Congenital Anomalies 0.809 0.469 – 1.4 0.448 15 124 exclusion phecode
749 Congenital anomalies of face and neck Congenital Anomalies 0.851 0.65 – 1.11 0.241 60 529 exclusion phecode
749.1 Cleft palate Congenital Anomalies 1 0.35 – 2.86 0.999 1 59 exclusion phecode
749.2 Congenital anomalies of skull and face bones Congenital Anomalies 0.674 0.335 – 1.35 0.267 10 88 exclusion phecode
750 Digestive congenital anomalies Congenital Anomalies 1.02 0.874 – 1.19 0.79 188 1087 exclusion phecode
750.1 Upper gastrointestinal congenital anomalies Congenital Anomalies 1.1 0.827 – 1.46 0.512 58 426 exclusion phecode
750.11 Esophageal atresia/tracheoesophageal fistula Congenital Anomalies 0.981 0.619 – 1.56 0.937 25 147 exclusion phecode
750.13 Congenital anomalies of mouth/tongue Congenital Anomalies 1.19 0.587 – 2.4 0.633 13 88 exclusion phecode
750.14 Congenital anomalies of esophagus Congenital Anomalies 0.856 0.564 – 1.3 0.467 26 163 exclusion phecode
750.15 Congenital anomalies of stomach Congenital Anomalies 1.57 0.833 – 2.94 0.164 11 81 exclusion phecode
750.2 Lower gastrointestinal congenital anomalies Congenital Anomalies 0.997 0.823 – 1.21 0.979 133 662 exclusion phecode
750.21 Congenital anomalies of intestine Congenital Anomalies 0.94 0.753 – 1.17 0.584 97 401 exclusion phecode
750.22
Congenital anomaly of gallbladder, bile ducts
Congenital anomaly of gallbladder, bile ducts, liver, pancreas
 Congenital Anomalies 1.01 0.721 – 1.43 0.932 40 265 exclusion phecode
751 Genitourinary congenital anomalies Congenital Anomalies 0.965 0.851 – 1.09 0.575 297 2129 exclusion phecode
751.1 Congenital anomalies of genital organs Congenital Anomalies 1.07 0.873 – 1.31 0.512 109 670 exclusion phecode
751.11 Congenital anomalies of female genital organs Congenital Anomalies 1.07 0.861 – 1.34 0.532 96 589 exclusion phecode
751.12 Congenital anomalies of male genital organs Congenital Anomalies 0.873 0.481 – 1.58 0.655 8 57 exclusion phecode
751.2 Congenital anomalies of urinary system Congenital Anomalies 0.913 0.781 – 1.07 0.256 189 1406 exclusion phecode
751.21 Cystic kidney disease Congenital Anomalies 0.942 0.788 – 1.13 0.516 144 1018 exclusion phecode
751.22 Other specified congenital anomalies of kidney Congenital Anomalies 0.716 0.482 – 1.06 0.0969 31 299 exclusion phecode
751.3 Obstructive genitourinary defect Congenital Anomalies 0.771 0.45 – 1.32 0.346 17 181 exclusion phecode
752 Nervous system congenital anomalies Congenital Anomalies 0.85 0.724 – 0.998 0.0478 170 1323 exclusion phecode
752.1 Neural tube defects Congenital Anomalies 0.848 0.711 – 1.01 0.0672 140 1086 exclusion phecode
752.11 Spina bifida Congenital Anomalies 1.56 0.976 – 2.48 0.0629 20 184 exclusion phecode
752.2
Other specified congenital anomalies of nervous
Other specified congenital anomalies of nervous system
 Congenital Anomalies 1.23 0.813 – 1.87 0.324 25 237 exclusion phecode
753 Congenital anomalies of the eye Congenital Anomalies 1.04 0.737 – 1.47 0.819 43 268 exclusion phecode
753.1 Congenital cataract and lens anomalies Congenital Anomalies 0.62 0.328 – 1.17 0.142 14 76 exclusion phecode
753.2 Congenital anomalies of posterior segment of eye Congenital Anomalies 1.78 0.82 – 3.87 0.144 12 79 exclusion phecode
754 Congenital musculoskeletal deformities of spine Congenital Anomalies 0.862 0.744 – 0.998 0.0476 212 1425 exclusion phecode
754.1 Lumbosacral spondylolysis, congenital Congenital Anomalies 1.21 0.831 – 1.76 0.322 37 172 exclusion phecode
754.2 Spondylolisthesis, congenital Congenital Anomalies 0.827 0.662 – 1.03 0.093 92 697 exclusion phecode
755 Congenital anomalies of limbs Congenital Anomalies 1.01 0.845 – 1.21 0.917 144 854 exclusion phecode
755.1 Congenital deformities of feet Congenital Anomalies 1.14 0.896 – 1.44 0.294 78 426 exclusion phecode
755.4
Congenital anomalies of upper limb, including
Congenital anomalies of upper limb, including shoulder girdle
 Congenital Anomalies 1.65 0.955 – 2.87 0.0725 14 78 exclusion phecode
755.6
Other congenital anomalies of lower limb
Other congenital anomalies of lower limb, including pelvic girdle
 Congenital Anomalies 0.696 0.505 – 0.96 0.0271 53 345 exclusion phecode
755.61 Congenital hip dysplasia and deformity Congenital Anomalies 0.642 0.425 – 0.968 0.0343 31 214 exclusion phecode
756 Other congenital musculoskeletal anomalies Congenital Anomalies 0.934 0.804 – 1.09 0.378 197 1459 exclusion phecode
756.1 Congenital anomalies of abdominal wall; diaphram Congenital Anomalies 1.16 0.512 – 2.61 0.728 5 69 exclusion phecode
756.2
Pectus and other congenital anomalies of
Pectus and other congenital anomalies of ribs/sternum
 Congenital Anomalies 0.82 0.313 – 2.15 0.685 5 46 exclusion phecode
756.3
Congenital anomalies of muscle, tendon, fascia
Congenital anomalies of muscle, tendon, fascia, and connective tissue
 Congenital Anomalies 1.18 0.867 – 1.61 0.291 51 352 exclusion phecode
756.5 Congenital osteodystrophies Congenital Anomalies 1 0.837 – 1.2 0.983 146 1113 exclusion phecode
757 Congenital anomalies of the integument Congenital Anomalies 0.832 0.625 – 1.11 0.206 57 519 exclusion phecode
758 Chromosomal anomalies and genetic disorders Congenital Anomalies 1.02 0.685 – 1.53 0.912 29 227 exclusion phecode
758.1 Chromosomal anomalies Congenital Anomalies 0.863 0.555 – 1.34 0.512 25 171 exclusion phecode
759 Other and unspecified congenital anomalies Congenital Anomalies 0.865 0.688 – 1.09 0.214 93 651 exclusion phecode
759.1 Anomalies of endocrine glands, congenital Congenital Anomalies 0.803 0.439 – 1.47 0.477 15 101 exclusion phecode
760 Back pain Symptoms 1.02 0.96 – 1.08 0.577 2895 2335 exclusion phecode
761 Cervicalgia Symptoms 1 0.939 – 1.07 0.992 1457 3753 exclusion phecode
763
Thoracic or lumbosacral neuritis or
Thoracic or lumbosacral neuritis or radiculitis, unspecified
 Symptoms 0.974 0.895 – 1.06 0.54 700 3237 exclusion phecode
764 Sciatica Symptoms 1 0.921 – 1.09 0.963 696 3329 exclusion phecode
765 Cervical radiculitis Symptoms 1.05 0.935 – 1.18 0.422 364 1909 exclusion phecode
766 Neuralgia, neuritis, and radiculitis NOS Symptoms 1.03 0.956 – 1.11 0.441 937 3581 exclusion phecode
767 Cervicocranial/Cervicobrachial syndrome Symptoms 1.25 0.818 – 1.9 0.305 29 163 exclusion phecode
769 Nonallopathic lesions NEC Symptoms 0.985 0.869 – 1.12 0.815 315 1557 exclusion phecode
770 Myalgia and myositis unspecified Symptoms 1 0.939 – 1.07 0.898 1172 3764 exclusion phecode
771 Musculoskeletal symptoms referable to limbs Symptoms 0.96 0.886 – 1.04 0.323 795 3404 exclusion phecode
771.1 Swelling of limb Symptoms 1 0.929 – 1.08 0.987 996 3442 exclusion phecode
771.2 Cramp of limb Symptoms 0.994 0.859 – 1.15 0.933 246 1245 exclusion phecode
772 Symptoms of the muscles Symptoms 1.02 0.925 – 1.13 0.664 482 2338 exclusion phecode
772.1 Muscular wasting and disuse atrophy Symptoms 0.987 0.773 – 1.26 0.914 74 344 exclusion phecode
772.2 Spasm of muscle Symptoms 0.92 0.829 – 1.02 0.114 442 2654 exclusion phecode
772.3 Muscle weakness Symptoms 0.97 0.88 – 1.07 0.536 514 2831 exclusion phecode
772.4 Rhabdomyolysis Symptoms 0.85 0.525 – 1.38 0.507 21 121 exclusion phecode
772.6 Facial weakness Symptoms 0.835 0.631 – 1.11 0.207 49 478 exclusion phecode
780 Hypothermia/Chills Symptoms 1.08 0.845 – 1.38 0.535 78 502 exclusion phecode
781
Symptoms involving nervous and musculoskeletal
Symptoms involving nervous and musculoskeletal systems
 Symptoms 1.09 0.985 – 1.2 0.0978 506 2894 exclusion phecode
781.1 Loss of height Symptoms 1.26 0.882 – 1.79 0.207 41 155 exclusion phecode
781.2 Abnormal posture Symptoms 1.3 0.731 – 2.29 0.375 18 65 exclusion phecode
782.3 Edema Symptoms 0.992 0.922 – 1.07 0.829 993 3758 exclusion phecode
782.6 Pallor and flushing Symptoms 1.16 1.01 – 1.33 0.0358 246 1277 exclusion phecode
783 Fever of unknown origin Symptoms 0.956 0.887 – 1.03 0.238 875 4312 exclusion phecode
783.1 Postprocedural fever Symptoms 0.719 0.499 – 1.03 0.0756 30 267 exclusion phecode
785 Abdominal pain Symptoms 0.992 0.937 – 1.05 0.776 2843 2389 exclusion phecode
788 Syncope and collapse Symptoms 1.05 0.963 – 1.14 0.279 696 3844 exclusion phecode
789 Nausea and vomiting Symptoms 0.975 0.917 – 1.04 0.407 1625 3592 exclusion phecode
789.1 Persistent vomiting Symptoms 0.864 0.709 – 1.05 0.148 105 868 exclusion phecode
790 Nonspecific findings on examination of blood Symptoms 0.963 0.867 – 1.07 0.473 456 2289 exclusion phecode
790.1 Elevated sedimentation rate Symptoms 1.07 0.774 – 1.47 0.692 53 265 exclusion phecode
790.6 Other abnormal blood chemistry Symptoms 1.01 0.945 – 1.07 0.834 1484 3576 exclusion phecode
790.8 Elevated C-reactive protein (CRP) Symptoms 0.866 0.621 – 1.21 0.396 44 317 exclusion phecode
790.9 Abnormal arterial blood gases Symptoms 1.62 1.03 – 2.55 0.0368 26 149 exclusion phecode
791 Gangrene Symptoms 1.1 0.773 – 1.56 0.599 34 303 exclusion phecode
792
Abnormal Papanicolaou smear of cervix and
Abnormal Papanicolaou smear of cervix and cervical HPV
 Genitourinary 1.09 1 – 1.19 0.0474 818 1941 exclusion phecode
792.1
Papanicolaou smear of cervix or vagina with
Papanicolaou smear of cervix or vagina with atypical squamous cells
 Genitourinary 1.13 0.99 – 1.28 0.0711 299 1190 exclusion phecode
794
Abnormal results of other function studies
Abnormal results of other function studies (bladder, pancreas, placenta, spleen, etc)
 Symptoms 0.916 0.704 – 1.19 0.512 68 588 exclusion phecode
795
Other and nonspecific abnormal cytological
Other and nonspecific abnormal cytological, histological and immunological findings
 Symptoms 1.09 0.99 – 1.2 0.0801 532 2912 exclusion phecode
795.8 Abnormal tumor markers Symptoms 0.997 0.844 – 1.18 0.97 168 1160 exclusion phecode
795.81 Elevated carcinoembryonic antigen [CEA] Symptoms 1.68 0.78 – 3.63 0.185 11 76 exclusion phecode
795.82 Elevated cancer antigen 125 [CA 125] Symptoms 1.3 0.897 – 1.87 0.167 34 294 exclusion phecode
796 Elevated prostate specific antigen [PSA] Genitourinary 1.15 0.941 – 1.4 0.176 171 450 exclusion phecode
797 Shock Symptoms 0.93 0.722 – 1.2 0.571 71 551 exclusion phecode
797.1 Cardiogenic shock Symptoms 0.839 0.549 – 1.28 0.415 22 199 exclusion phecode
798 Malaise and fatigue Symptoms 0.975 0.921 – 1.03 0.392 2324 2907 exclusion phecode
798.1 Chronic fatigue syndrome Symptoms 1.05 0.938 – 1.17 0.406 390 1817 exclusion phecode
800 Fracture of lower limb Injuries & Poisonings 1.05 0.949 – 1.17 0.33 448 2367 exclusion phecode
800.1 Fracture of neck of femur Injuries & Poisonings 0.88 0.705 – 1.1 0.258 110 472 exclusion phecode
800.2 Fracture of unspecified part of femur Injuries & Poisonings 0.947 0.77 – 1.16 0.606 115 610 exclusion phecode
800.3 Fracture of tibia and fibula Injuries & Poisonings 1.2 1.01 – 1.42 0.034 155 853 exclusion phecode
800.4 Fracture of patella Injuries & Poisonings 1.14 0.894 – 1.45 0.294 84 360 exclusion phecode
801 Fracture of ankle and foot Injuries & Poisonings 1.12 1.02 – 1.23 0.021 539 2535 exclusion phecode
801.1 Fracture of foot Injuries & Poisonings 1.14 0.988 – 1.32 0.0721 225 1248 exclusion phecode
802 Fracture of pelvis Injuries & Poisonings 1.02 0.78 – 1.33 0.889 66 359 exclusion phecode
803 Fracture of upper limb Injuries & Poisonings 0.982 0.886 – 1.09 0.73 452 2101 exclusion phecode
803.1 Fracture of humerus Injuries & Poisonings 0.852 0.711 – 1.02 0.0827 146 764 exclusion phecode
803.2 Fracture of radius and ulna Injuries & Poisonings 1.06 0.934 – 1.21 0.353 291 1233 exclusion phecode
803.21 Colles' fracture Injuries & Poisonings 0.979 0.776 – 1.23 0.856 98 337 exclusion phecode
803.3 Fracture of clavicle or scapula Injuries & Poisonings 1.04 0.833 – 1.3 0.717 87 393 exclusion phecode
804 Fracture of hand or wrist Injuries & Poisonings 1.05 0.933 – 1.18 0.419 349 1557 exclusion phecode
805
Fracture of vertebral column without mention of
Fracture of vertebral column without mention of spinal cord injury
 Injuries & Poisonings 1.12 0.971 – 1.3 0.119 231 1248 exclusion phecode
807 Fracture of ribs Injuries & Poisonings 1.12 0.925 – 1.36 0.246 118 588 exclusion phecode
809 Fracture of unspecified bones Injuries & Poisonings 1.01 0.917 – 1.11 0.826 504 2804 exclusion phecode
816 Cerebral laceration and contusion Injuries & Poisonings 2.2 0.81 – 5.97 0.122 8 42 exclusion phecode
817 Concussion Injuries & Poisonings 0.912 0.782 – 1.06 0.243 191 1104 exclusion phecode
818 Intracranial hemorrhage (injury) Injuries & Poisonings 1.04 0.777 – 1.4 0.782 53 295 exclusion phecode
818.1 Subdural hemorrhage (injury) Injuries & Poisonings 1.09 0.567 – 2.11 0.788 17 81 exclusion phecode
818.2 Subarachnoid hemorrhage (injury) Injuries & Poisonings 0.756 0.399 – 1.43 0.391 12 92 exclusion phecode
819
Skull and face fracture and other intercranial
Skull and face fracture and other intercranial injury
 Injuries & Poisonings 0.966 0.864 – 1.08 0.549 364 2249 exclusion phecode
830 Dislocation Injuries & Poisonings 1.04 0.96 – 1.13 0.324 727 3534 exclusion phecode
835 Internal derangement of knee Injuries & Poisonings 1.01 0.91 – 1.12 0.89 468 2207 exclusion phecode
836 Traumatic arthropathy Injuries & Poisonings 0.915 0.721 – 1.16 0.465 88 480 exclusion phecode
840 Sprains and strains Injuries & Poisonings 0.979 0.921 – 1.04 0.487 1647 3386 exclusion phecode
840.1 Muscle/tendon sprain Injuries & Poisonings 1.05 0.864 – 1.28 0.62 140 472 exclusion phecode
840.2 Rotator cuff (capsule) sprain Injuries & Poisonings 0.985 0.871 – 1.11 0.805 336 1395 exclusion phecode
840.3 Joint/ligament sprain Injuries & Poisonings 1.01 0.918 – 1.11 0.845 526 2274 exclusion phecode
841 Sprains and strains of back and neck Injuries & Poisonings 0.95 0.843 – 1.07 0.401 369 1632 exclusion phecode
842 Other sprains and strains Injuries & Poisonings 0.929 0.816 – 1.06 0.261 309 1297 exclusion phecode
850 Hemorrhage or hematoma complicating a procedure Injuries & Poisonings 1.07 0.933 – 1.22 0.341 249 2227 exclusion phecode
851
Complications of transplants and reattached
Complications of transplants and reattached limbs
 Injuries & Poisonings 0.988 0.879 – 1.11 0.844 324 2779 exclusion phecode
853 Complication of colostomy or enterostomy Injuries & Poisonings 0.872 0.642 – 1.18 0.381 48 455 exclusion phecode
854
Complications of cardiac/vascular device
Complications of cardiac/vascular device, implant, and graft
 Injuries & Poisonings 1.08 0.925 – 1.25 0.343 187 1961 exclusion phecode
855
Complication of nervous system device, implant
Complication of nervous system device, implant, and graft
 Injuries & Poisonings 1.07 0.675 – 1.7 0.773 15 264 exclusion phecode
856
Vascular complications of surgery and medical
Vascular complications of surgery and medical procedures
 Injuries & Poisonings 1.06 0.742 – 1.5 0.759 36 326 exclusion phecode
857
Mechanical complication of unspecified
Mechanical complication of unspecified genitourinary device, implant, and graft
 Injuries & Poisonings 1.01 0.849 – 1.19 0.94 143 1432 exclusion phecode
858 Complication of internal orthopedic device Injuries & Poisonings 1.07 0.94 – 1.22 0.307 261 2251 exclusion phecode
859
Complication due to other implant and internal
Complication due to other implant and internal device
 Injuries & Poisonings 1.06 0.928 – 1.21 0.381 238 2300 exclusion phecode
860 Bone marrow or stem cell transplant Neoplasms 1.02 0.666 – 1.55 0.943 24 159 exclusion phecode
870 Open wounds of head; neck; and trunk Injuries & Poisonings 0.997 0.911 – 1.09 0.945 578 3756 exclusion phecode
870.1 Open wound or laceration of eye or eyelid Injuries & Poisonings 0.793 0.519 – 1.21 0.284 32 174 exclusion phecode
870.2 Open wound of ear Injuries & Poisonings 0.654 0.407 – 1.05 0.0781 27 153 exclusion phecode
870.3 Other open wound of head and face Injuries & Poisonings 1.04 0.9 – 1.2 0.609 230 1381 exclusion phecode
870.4 Open wound of nose and sinus Injuries & Poisonings 0.792 0.543 – 1.16 0.227 32 236 exclusion phecode
870.5 Open wound of lip and mouth Injuries & Poisonings 1.21 0.87 – 1.69 0.255 46 248 exclusion phecode
870.6 Open wound of neck Injuries & Poisonings 0.745 0.417 – 1.33 0.321 11 172 exclusion phecode
870.8 Open wound of genital organs Injuries & Poisonings 1.41 0.941 – 2.12 0.096 23 184 exclusion phecode
871 Open wounds of extremities Injuries & Poisonings 0.957 0.876 – 1.05 0.337 590 3431 exclusion phecode
871.1 Open wound of hand except finger(s) Injuries & Poisonings 0.877 0.715 – 1.08 0.212 113 605 exclusion phecode
871.2 Open wound of finger(s) Injuries & Poisonings 0.981 0.843 – 1.14 0.8 206 1060 exclusion phecode
871.3 Open wound of foot except toe(s) alone Injuries & Poisonings 0.981 0.751 – 1.28 0.886 63 485 exclusion phecode
871.4 Open wound of toe(s) Injuries & Poisonings 0.966 0.718 – 1.3 0.82 47 380 exclusion phecode
872 Traumatic amputation Injuries & Poisonings 1.2 0.85 – 1.69 0.301 38 449 exclusion phecode
874 Complication of amputation stump Injuries & Poisonings 1.24 0.665 – 2.32 0.497 11 131 exclusion phecode
875 Non-healing surgical wound Injuries & Poisonings 1.5 1.12 – 2 0.00661 51 587 exclusion phecode
876
Posttraumatic wound infection not elsewhere
Posttraumatic wound infection not elsewhere classified
 Injuries & Poisonings 0.966 0.772 – 1.21 0.761 86 852 exclusion phecode
907 Injuries to the nervous system Injuries & Poisonings 0.915 0.743 – 1.13 0.401 103 947 exclusion phecode
910 Superficial injury, infected Injuries & Poisonings 1.25 0.773 – 2.04 0.358 22 127 exclusion phecode
911 Blister Injuries & Poisonings 1.04 0.788 – 1.38 0.772 51 358 exclusion phecode
912 Insect bite Injuries & Poisonings 0.916 0.761 – 1.1 0.351 143 690 exclusion phecode
913 Toxic effect of venom Injuries & Poisonings 1.02 0.815 – 1.26 0.891 102 485 exclusion phecode
916 Contusion Injuries & Poisonings 1.01 0.934 – 1.08 0.879 909 4049 exclusion phecode
930 Allergic reaction to food Injuries & Poisonings 1.05 0.872 – 1.26 0.615 162 646 exclusion phecode
931
Contact dermatitis and other eczema due to
Contact dermatitis and other eczema due to plants [except food]
 Dermatologic 1.02 0.87 – 1.21 0.77 189 652 exclusion phecode
938 Dermatitis due to solar radiation Dermatologic 0.975 0.907 – 1.05 0.488 1421 2072 exclusion phecode
938.1 Acute dermatitis due to solar radiation Dermatologic 1.12 0.783 – 1.61 0.527 45 211 exclusion phecode
938.2 Chronic dermatitis due to solar radiation Dermatologic 0.974 0.905 – 1.05 0.473 1388 2050 exclusion phecode
939
Atopic/contact dermatitis due to other or
Atopic/contact dermatitis due to other or unspecified
 Dermatologic 1.01 0.948 – 1.08 0.684 1655 2206 exclusion phecode
939.1 Contact and allergic dermatitis of eyelid Dermatologic 0.984 0.639 – 1.51 0.94 37 103 exclusion phecode
941 Adverse reaction to serum or vaccine Injuries & Poisonings 0.806 0.553 – 1.17 0.26 29 189 exclusion phecode
942 Infusion and transfusion reaction Injuries & Poisonings 1.26 0.848 – 1.88 0.251 33 175 exclusion phecode
946 Anaphylactic shock NOS Injuries & Poisonings 0.975 0.781 – 1.22 0.821 116 454 exclusion phecode
947 Urticaria Dermatologic 0.994 0.864 – 1.14 0.932 268 1087 exclusion phecode
949 Allergies, other Injuries & Poisonings 1.05 0.984 – 1.13 0.139 1616 2207 exclusion phecode
952
Spinal cord injury without evidence of spinal
Spinal cord injury without evidence of spinal bone injury
 Injuries & Poisonings 1.04 0.805 – 1.35 0.751 60 443 exclusion phecode
957 Injury to other and unspecified nerves Injuries & Poisonings 1.4 0.863 – 2.28 0.172 20 137 exclusion phecode
958
Certain early complications of trauma or
Certain early complications of trauma or procedure
 Injuries & Poisonings 0.903 0.753 – 1.08 0.267 137 1264 exclusion phecode
958.1 Postoperative shock Injuries & Poisonings 0.83 0.517 – 1.33 0.44 25 148 exclusion phecode
958.2 Traumatic and surgical subcutaneous emphysema Injuries & Poisonings 0.717 0.387 – 1.33 0.292 15 101 exclusion phecode
960 Poisoning by antibiotics Injuries & Poisonings 0.99 0.881 – 1.11 0.867 330 2380 exclusion phecode
960.1
Adverse effects of antibacterials (not
Adverse effects of antibacterials (not penicillins)
 Injuries & Poisonings 0.825 0.627 – 1.09 0.17 61 425 exclusion phecode
960.2 Allergy/adverse effect of penicillin Injuries & Poisonings 1.03 0.894 – 1.19 0.667 210 1760 exclusion phecode
961 Poisoning by other anti-infectives Injuries & Poisonings 1.16 0.952 – 1.42 0.14 115 641 exclusion phecode
961.1 Poisoning/allergy of sulfonamides Injuries & Poisonings 1.11 0.941 – 1.31 0.212 162 1300 exclusion phecode
962 Poisoning by hormones and synthetic substitutes Injuries & Poisonings 0.913 0.765 – 1.09 0.312 148 898 exclusion phecode
962.1
Adrenal cortical steroids causing adverse
Adrenal cortical steroids causing adverse effects in therapeutic use
 Injuries & Poisonings 1.05 0.816 – 1.35 0.701 72 400 exclusion phecode
962.2
Insulins and antidiabetic agents causing
Insulins and antidiabetic agents causing adverse effects in therapeutic use
 Injuries & Poisonings 0.63 0.352 – 1.13 0.119 17 120 exclusion phecode
962.3
Hormones and synthetic substitutes causing
Hormones and synthetic substitutes causing adverse effects in therapeutic use
 Injuries & Poisonings 0.79 0.627 – 0.995 0.0448 87 521 exclusion phecode
963 Poisoning by primarily systemic agents Injuries & Poisonings 1.01 0.908 – 1.13 0.83 388 2640 exclusion phecode
963.1
Antineoplastic and immunosuppressive drugs
Antineoplastic and immunosuppressive drugs causing adverse effects
 Injuries & Poisonings 1 0.896 – 1.12 0.998 375 2587 exclusion phecode
964
Poisoning by agents primarily affecting blood
Poisoning by agents primarily affecting blood constituents
 Injuries & Poisonings 1.03 0.834 – 1.27 0.785 101 714 exclusion phecode
964.1 Anticoagulants causing adverse effects Injuries & Poisonings 1.04 0.836 – 1.3 0.707 91 675 exclusion phecode
965
Poisoning by analgesics, antipyretics, and
Poisoning by analgesics, antipyretics, and antirheumatics
 Injuries & Poisonings 1.17 0.976 – 1.41 0.0883 134 970 exclusion phecode
965.1
Opiates and related narcotics causing adverse
Opiates and related narcotics causing adverse effects in therapeutic use
 Injuries & Poisonings 1.05 0.903 – 1.22 0.526 192 1639 exclusion phecode
965.3
Salicylates causing adverse effects in
Salicylates causing adverse effects in therapeutic use
 Injuries & Poisonings 1.57 0.953 – 2.59 0.0767 19 118 exclusion phecode
966
Poisoning by anticonvulsants and
Poisoning by anticonvulsants and anti-Parkinsonism drugs
 Injuries & Poisonings 0.774 0.466 – 1.29 0.322 19 114 exclusion phecode
967
Adverse effects of sedatives or other central
Adverse effects of sedatives or other central nervous system depressants and anesthetics
 Injuries & Poisonings 0.846 0.723 – 0.99 0.0365 188 1439 exclusion phecode
969 Poisoning by psychotropic agents Injuries & Poisonings 0.818 0.588 – 1.14 0.235 45 285 exclusion phecode
971
Poisoning by drugs primarily affecting the
Poisoning by drugs primarily affecting the autonomic nervous system
 Injuries & Poisonings 1.22 0.717 – 2.08 0.463 16 61 exclusion phecode
972
Poisoning by agents primarily affecting the
Poisoning by agents primarily affecting the cardiovascular system
 Injuries & Poisonings 1.27 0.931 – 1.73 0.132 58 283 exclusion phecode
972.1
Cardiac rhythm regulators causing adverse
Cardiac rhythm regulators causing adverse effects in therapeutic use
 Injuries & Poisonings 0.563 0.256 – 1.24 0.153 14 69 exclusion phecode
972.6 Antihypertensive agents causing adverse effects Injuries & Poisonings 1.12 0.725 – 1.74 0.605 28 113 exclusion phecode
974
Poisoning by water, mineral, and uric acid
Poisoning by water, mineral, and uric acid metabolism drugs
 Injuries & Poisonings 0.613 0.348 – 1.08 0.0911 15 126 exclusion phecode
975
Poisoning by agents primarily acting on the
Poisoning by agents primarily acting on the smooth and skeletal muscles and respiratory system
 Injuries & Poisonings 1.11 0.639 – 1.93 0.712 20 78 exclusion phecode
976
Poisoning by agents primarily affecting skin &
Poisoning by agents primarily affecting skin & mucous membrane, ophthalmological, otorhinolaryngological, & dental drugs
 Injuries & Poisonings 0.876 0.511 – 1.5 0.631 10 93 exclusion phecode
977 Personal history of allergy to medicinal agents Injuries & Poisonings 1.02 0.894 – 1.17 0.754 255 1865 exclusion phecode
979 Adverse drug events and drug allergies Injuries & Poisonings 1.04 0.95 – 1.14 0.398 589 3409 exclusion phecode
980
Encounter for long-term (current) use of
Encounter for long-term (current) use of antibiotics
 Infectious Diseases 1.1 0.926 – 1.3 0.288 150 1341 exclusion phecode
985 Toxic effect of other metals Injuries & Poisonings 0.572 0.275 – 1.19 0.135 9 67 exclusion phecode
989
Toxic effect of other substances, chiefly
Toxic effect of other substances, chiefly nonmedicinal as to source
 Injuries & Poisonings 0.922 0.594 – 1.43 0.718 31 154 exclusion phecode
990 Effects radiation NOS Injuries & Poisonings 1.07 0.959 – 1.19 0.235 397 3485 exclusion phecode
994 Sepsis and SIRS Injuries & Poisonings 0.894 0.782 – 1.02 0.104 240 2205 exclusion phecode
994.1 Systemic inflammatory response syndrome (SIRS) Injuries & Poisonings 1.57 1.09 – 2.26 0.0148 38 309 exclusion phecode
994.2 Sepsis Injuries & Poisonings 0.866 0.754 – 0.994 0.0408 225 2086 exclusion phecode
994.21 Septic shock Injuries & Poisonings 0.718 0.535 – 0.965 0.0282 48 603 exclusion phecode
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