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Scores Sleeplessness / insomnia Michigan Genomics Initiative Freeze 3 (MGI) PheWAS analysis

Sleeplessness / insomnia — Michigan Genomics Initiative Freeze 3 (MGI) PRS PheWAS

PRS model
PRS ID exprsweb-insomnia-1200-plink-mgi-freeze3-20211120Legacy PLINKC+T (GT)UK Biobank GWAS

Evaluation cohort: Michigan Genomics Initiative Freeze 3 (MGI).

This page pairs the PheWAS plot with the full sortable table for the all-subject and exclusion scans.

Read the all-subject and exclusion scans separately. The combined view is only a browsing aid, and the selected-phecode panel below is only meaningful when the same phecode exists in both scans.

ExPRS exclusion definition

Exclusion cohort: individuals without Sleeplessness / insomnia.

For this ExPRS, the exclusion sensitivity scan removes individuals with the exposure itself before rerunning the PheWAS. This is an exposure-based sensitivity analysis rather than a diagnosis-based exclusion.

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336 rows visible 17 categories
Phecode Description Category OR 95% CI P value Cases Controls Analysis Link
008 Intestinal infection Infectious Diseases 1.02 0.983 – 1.06 0.292 3004 29292 all phecode
008.5 Bacterial enteritis Infectious Diseases 1.02 0.961 – 1.08 0.555 1322 13162 all phecode
008.52 Intestinal infection due to C. difficile Infectious Diseases 1.02 0.954 – 1.08 0.598 1046 10455 all phecode
008.6 Viral Enteritis Infectious Diseases 1.03 0.959 – 1.11 0.39 770 7676 all phecode
010 Tuberculosis Infectious Diseases 0.982 0.856 – 1.13 0.79 244 2425 all phecode
031 Diseases due to other mycobacteria Infectious Diseases 0.988 0.794 – 1.23 0.917 86 855 all phecode
038 Septicemia Infectious Diseases 1.05 1.01 – 1.09 0.0221 2582 24779 all phecode
038.1 Gram negative septicemia Infectious Diseases 1.04 0.952 – 1.14 0.383 568 5629 all phecode
038.2 Gram positive septicemia Infectious Diseases 1.04 0.911 – 1.19 0.556 235 2350 all phecode
038.3 Bacteremia Infectious Diseases 1.03 0.967 – 1.09 0.398 1210 12079 all phecode
041 Bacterial infection NOS Infectious Diseases 1.05 1.02 – 1.08 0.000971 5750 38799 all phecode
041.1 Staphylococcus infections Infectious Diseases 1.07 1.02 – 1.12 0.0103 1707 16977 all phecode
041.11 Methicillin sensitive Staphylococcus aureus Infectious Diseases 1.04 0.97 – 1.11 0.284 920 9192 all phecode
041.12 Methicillin resistant Staphylococcus aureus Infectious Diseases 1.06 0.988 – 1.14 0.101 783 7812 all phecode
041.2 Streptococcus infection Infectious Diseases 1.03 0.983 – 1.09 0.194 1632 16287 all phecode
041.21 Rheumatic fever / chorea Infectious Diseases 1.04 0.914 – 1.18 0.554 257 2554 all phecode
041.4 E. coli Infectious Diseases 1.06 0.999 – 1.13 0.0528 1175 11680 all phecode
041.8 H. pylori Infectious Diseases 1.02 0.899 – 1.17 0.721 257 2521 all phecode
041.9 Infection with drug-resistant microorganisms Infectious Diseases 1.05 0.944 – 1.17 0.366 387 3864 all phecode
053 Herpes zoster Infectious Diseases 1.03 0.98 – 1.09 0.234 1560 15184 all phecode
053.1 Herpes zoster with nervous system complications Infectious Diseases 1.09 0.944 – 1.25 0.25 220 2169 all phecode
054 Herpes simplex Infectious Diseases 0.974 0.925 – 1.03 0.328 1593 15600 all phecode
070 Viral hepatitis Infectious Diseases 1.06 0.989 – 1.14 0.0973 829 8280 all phecode
070.1 Viral hepatitis A Infectious Diseases 0.939 0.751 – 1.18 0.583 87 860 all phecode
070.2 Viral hepatitis B Infectious Diseases 1.02 0.882 – 1.17 0.823 215 2138 all phecode
070.3 Viral hepatitis C Infectious Diseases 1.12 1.02 – 1.23 0.0166 528 5280 all phecode
070.4 Chronic hepatitis Infectious Diseases 0.961 0.829 – 1.11 0.602 197 1964 all phecode
070.9 Hepatitis NOS Infectious Diseases 1.05 0.991 – 1.12 0.0957 1145 11381 all phecode
071 Human immunodeficiency virus [HIV] disease Infectious Diseases 0.902 0.759 – 1.07 0.241 145 1450 all phecode
071.1 HIV infection, symptomatic Infectious Diseases 0.86 0.712 – 1.04 0.119 117 1163 all phecode
078 Viral warts & HPV Infectious Diseases 0.979 0.944 – 1.01 0.241 3434 29624 all phecode
079 Viral infection Infectious Diseases 0.993 0.967 – 1.02 0.627 6664 35342 all phecode
079.1 Varicella infection Infectious Diseases 0.98 0.947 – 1.01 0.239 3793 31251 all phecode
079.2 Infectious mononucleosis Infectious Diseases 0.958 0.847 – 1.08 0.488 283 2723 all phecode
079.9 Viremia, NOS Infectious Diseases 1.03 0.956 – 1.1 0.456 838 8253 all phecode
080 Postoperative infection Infectious Diseases 1.06 1.02 – 1.11 0.00289 2619 26065 all phecode
081
Infection/inflammation of internal prosthetic
Infection/inflammation of internal prosthetic device; implant; and graft
 Infectious Diseases 1.09 1.03 – 1.14 0.00198 1589 15884 all phecode
090
Sexually transmitted infections (not HIV or
Sexually transmitted infections (not HIV or hepatitis)
 Infectious Diseases 0.92 0.861 – 0.984 0.0154 965 9630 all phecode
110 Dermatophytosis / Dermatomycosis Infectious Diseases 0.974 0.94 – 1.01 0.155 3544 30054 all phecode
110.1 Dermatophytosis Infectious Diseases 0.981 0.945 – 1.02 0.302 3241 27244 all phecode
110.11 Dermatophytosis of nail Infectious Diseases 0.994 0.948 – 1.04 0.795 2044 16765 all phecode
110.12 Althete's foot Infectious Diseases 1 0.936 – 1.08 0.917 899 8043 all phecode
110.13 Dermatophytosis of the body Infectious Diseases 0.99 0.92 – 1.07 0.788 790 7827 all phecode
110.2 Dermatomycoses Infectious Diseases 0.865 0.779 – 0.96 0.0065 398 3971 all phecode
112 Candidiasis Infectious Diseases 1.03 0.999 – 1.07 0.0586 3685 30495 all phecode
112.3 Candidiasis of skin and nails Infectious Diseases 1.05 0.97 – 1.14 0.23 682 6732 all phecode
117 Mycoses Infectious Diseases 0.986 0.906 – 1.07 0.739 608 6069 all phecode
117.1 Histoplasmosis Infectious Diseases 0.988 0.786 – 1.24 0.915 81 801 all phecode
117.4 Aspergillosis Infectious Diseases 1.03 0.867 – 1.23 0.715 140 1387 all phecode
130 Spirochetal infection Infectious Diseases 0.892 0.762 – 1.04 0.153 168 1677 all phecode
130.1 Lyme disease Infectious Diseases 0.874 0.724 – 1.06 0.165 116 1160 all phecode
131 Protozoan infection Infectious Diseases 1.1 0.851 – 1.42 0.473 61 610 all phecode
132 Infestation (lice, mites) Infectious Diseases 0.889 0.768 – 1.03 0.116 195 1948 all phecode
134 Helminthiases Infectious Diseases 0.837 0.665 – 1.05 0.131 83 812 all phecode
134.1 Intestinal helminthiases Infectious Diseases 0.926 0.694 – 1.23 0.6 53 513 all phecode
136 Other infectious and parasitic diseases Infectious Diseases 1.06 1.02 – 1.1 0.00305 3279 32486 all phecode
145 Cancer of mouth Neoplasms 0.977 0.925 – 1.03 0.41 1481 14725 all phecode
145.1 Cancer of lip Neoplasms 0.935 0.732 – 1.19 0.588 76 750 all phecode
145.2 Cancer of tongue Neoplasms 0.943 0.868 – 1.02 0.164 645 6430 all phecode
145.3 Cancer of major salivary glands Neoplasms 0.999 0.895 – 1.11 0.979 361 3597 all phecode
145.4 Cancer of the gums Neoplasms 0.903 0.769 – 1.06 0.21 166 1632 all phecode
145.5 Cancer of the mouth floor Neoplasms 1.06 0.921 – 1.22 0.41 206 2048 all phecode
149 Cancer of larynx, pharynx, nasal cavities Neoplasms 0.941 0.888 – 0.997 0.0386 1290 12873 all phecode
149.1 Cancer of oropharynx Neoplasms 1.04 0.933 – 1.17 0.451 350 3499 all phecode
149.2 Cancer of nasopharynx Neoplasms 0.951 0.772 – 1.17 0.635 100 1000 all phecode
149.3 Cancer of hypopharynx Neoplasms 0.84 0.666 – 1.06 0.142 82 819 all phecode
149.4 Cancer of larynx Neoplasms 0.935 0.841 – 1.04 0.216 386 3857 all phecode
149.5
Hx of malignant neoplasm of oral cavity and
Hx of malignant neoplasm of oral cavity and pharynx
 Neoplasms 0.92 0.842 – 1 0.0619 552 5505 all phecode
149.9 Cancer of of nasal cavities Neoplasms 0.937 0.82 – 1.07 0.34 240 2398 all phecode
150 Cancer of esophagus Neoplasms 0.964 0.872 – 1.06 0.467 433 4315 all phecode
151 Cancer of stomach Neoplasms 1.13 1.03 – 1.24 0.0126 498 4962 all phecode
153 Colorectal cancer Neoplasms 1.05 0.992 – 1.11 0.097 1458 14383 all phecode
153.2 Colon cancer Neoplasms 1.04 0.976 – 1.1 0.237 1160 11472 all phecode
153.3
Malignant neoplasm of rectum, rectosigmoid
Malignant neoplasm of rectum, rectosigmoid junction, and anus
 Neoplasms 1.04 0.97 – 1.12 0.254 815 8093 all phecode
155 Cancer of liver and intrahepatic bile duct Neoplasms 1.07 0.972 – 1.17 0.173 511 5097 all phecode
155.1 Malignant neoplasm of liver, primary Neoplasms 1.11 0.995 – 1.25 0.061 344 3433 all phecode
157 Pancreatic cancer Neoplasms 1.01 0.917 – 1.11 0.884 503 5005 all phecode
158
Neoplasm of unspecified nature of digestive
Neoplasm of unspecified nature of digestive system
 Neoplasms 1.09 1.03 – 1.14 0.00177 1623 15759 all phecode
159
Malignant neoplasm of other and ill-defined
Malignant neoplasm of other and ill-defined sites within the digestive organs and peritoneum
 Neoplasms 1.02 0.973 – 1.07 0.385 1818 17869 all phecode
159.2
Malignant neoplasm of small intestine
Malignant neoplasm of small intestine, including duodenum
 Neoplasms 1.07 0.931 – 1.23 0.342 221 2206 all phecode
159.3
Malignant neoplasm of gallbladder and
Malignant neoplasm of gallbladder and extrahepatic bile ducts
 Neoplasms 0.943 0.8 – 1.11 0.48 158 1578 all phecode
159.4
Malignant neoplasm of retroperitoneum and
Malignant neoplasm of retroperitoneum and peritoneum
 Neoplasms 0.879 0.778 – 0.993 0.0388 293 2920 all phecode
164 Cancer of intrathoracic organs Neoplasms 1.15 0.96 – 1.38 0.13 133 1324 all phecode
165 Cancer within the respiratory system Neoplasms 1.04 0.984 – 1.1 0.161 1336 13340 all phecode
165.1 Cancer of bronchus; lung Neoplasms 1.05 0.983 – 1.12 0.152 1057 10552 all phecode
170 Cancer of bone and connective tissue Neoplasms 0.974 0.927 – 1.02 0.297 1792 17850 all phecode
170.1 Bone cancer Neoplasms 0.953 0.884 – 1.03 0.209 773 7690 all phecode
170.2 Cancer of connective tissue Neoplasms 0.97 0.915 – 1.03 0.309 1266 12632 all phecode
172 Skin cancer Neoplasms 0.96 0.937 – 0.985 0.00157 8608 33186 all phecode
172.1 Melanomas of skin, dx or hx Neoplasms 0.95 0.922 – 0.979 0.00085 5330 30106 all phecode
172.11 Melanomas of skin Neoplasms 0.936 0.901 – 0.972 0.000589 3100 25064 all phecode
172.2 Other non-epithelial cancer of skin Neoplasms 0.969 0.943 – 0.996 0.0243 7095 30462 all phecode
172.21 Basal cell carcinoma Neoplasms 0.951 0.918 – 0.986 0.00635 3690 23868 all phecode
172.22 Squamous cell carcinoma Neoplasms 0.97 0.929 – 1.01 0.171 2414 17683 all phecode
172.3 Carcinoma in situ of skin Neoplasms 1.01 0.957 – 1.07 0.706 1482 12326 all phecode
173 Neoplasm of uncertain behavior of skin Neoplasms 1.01 0.966 – 1.06 0.596 1997 18755 all phecode
174 Breast cancer Neoplasms 0.98 0.943 – 1.02 0.319 3186 15514 all phecode
174.1 Breast cancer [female] Neoplasms 0.982 0.944 – 1.02 0.384 3036 14701 all phecode
174.11 Malignant neoplasm of female breast Neoplasms 0.987 0.948 – 1.03 0.542 2991 14639 all phecode
174.3 Neoplasm of uncertain behavior of breast Neoplasms 0.966 0.84 – 1.11 0.627 233 2307 all phecode
175 Acquired absence of breast Neoplasms 0.969 0.904 – 1.04 0.371 919 8920 all phecode
180 Cervical cancer and dysplasia Neoplasms 1.03 0.972 – 1.09 0.336 1431 12185 all phecode
180.1 Cervical cancer Neoplasms 1.03 0.941 – 1.14 0.492 500 4982 all phecode
180.3
Cervical intraepithelial neoplasia [CIN]
Cervical intraepithelial neoplasia [CIN] [Cervical dysplasia]
 Neoplasms 1.02 0.959 – 1.09 0.48 1048 9323 all phecode
182 Malignant neoplasm of uterus Neoplasms 1.03 0.96 – 1.12 0.372 765 7613 all phecode
184 Cancer of other female genital organs Neoplasms 0.933 0.878 – 0.991 0.0243 1191 11592 all phecode
184.1
Malignant neoplasm of ovary and other uterine
Malignant neoplasm of ovary and other uterine adnexa
 Neoplasms 0.918 0.842 – 1 0.0523 573 5719 all phecode
184.11 Malignant neoplasm of ovary Neoplasms 0.899 0.814 – 0.994 0.0376 432 4309 all phecode
184.2
Cancer of other female genital organs
Cancer of other female genital organs (excluding uterus and ovary)
 Neoplasms 0.981 0.902 – 1.07 0.652 608 6057 all phecode
185 Cancer of prostate Neoplasms 0.994 0.952 – 1.04 0.795 2901 10342 all phecode
187 Cancer of other male genital organs Neoplasms 1.06 0.948 – 1.19 0.3 339 3384 all phecode
187.1
Malignant neoplasm of unspecified male genital
Malignant neoplasm of unspecified male genital organ
 Neoplasms 1.08 0.888 – 1.32 0.433 115 1141 all phecode
187.2 Malignant neoplasm of testis Neoplasms 1.02 0.87 – 1.18 0.849 183 1830 all phecode
187.8
Neoplasm of uncertain behavior of male genital
Neoplasm of uncertain behavior of male genital organs
 Neoplasms 1.01 0.766 – 1.33 0.947 57 562 all phecode
189
Cancer of urinary organs (incl. kidney and
Cancer of urinary organs (incl. kidney and bladder)
 Neoplasms 1.04 0.996 – 1.08 0.0778 2923 23541 all phecode
189.1 Cancer of kidney and renal pelvis Neoplasms 1.04 0.988 – 1.1 0.129 1450 14437 all phecode
189.11 Malignant neoplasm of kidney, except pelvis Neoplasms 1.03 0.972 – 1.09 0.309 1267 12655 all phecode
189.12 Malignant neoplasm of renal pelvis Neoplasms 1.02 0.89 – 1.16 0.793 237 2347 all phecode
189.2 Cancer of bladder Neoplasms 1.02 0.971 – 1.07 0.428 1783 15224 all phecode
189.21 Malignant neoplasm of bladder Neoplasms 1.02 0.972 – 1.08 0.39 1657 14178 all phecode
189.4 Malignant neoplasm of other urinary organs Neoplasms 0.994 0.917 – 1.08 0.891 678 6586 all phecode
190 Cancer of eye Neoplasms 1.09 0.911 – 1.31 0.34 138 1374 all phecode
191
Manlignant and unknown neoplasms of brain and
Manlignant and unknown neoplasms of brain and nervous system
 Neoplasms 1.01 0.946 – 1.07 0.798 1078 10771 all phecode
191.1 Cancer of brain and nervous system Neoplasms 1.02 0.947 – 1.11 0.554 706 7052 all phecode
191.11 Cancer of brain Neoplasms 1.05 0.961 – 1.14 0.304 600 5996 all phecode
193 Thyroid cancer Neoplasms 1.03 0.964 – 1.1 0.366 945 9393 all phecode
194 Cancer of other endocrine glands Neoplasms 1.1 1.01 – 1.2 0.0252 579 5759 all phecode
195 Cancer, suspected or other Neoplasms 1 0.982 – 1.02 0.766 16962 26401 all phecode
195.1 Malignant neoplasm, other Neoplasms 1 0.982 – 1.02 0.813 16670 26384 all phecode
195.3 Malignant neoplasm of head, face, and neck Neoplasms 0.959 0.9 – 1.02 0.198 1103 9766 all phecode
196 Radiotherapy Neoplasms 0.957 0.916 – 0.999 0.0454 2427 17006 all phecode
197 Chemotherapy Neoplasms 0.991 0.96 – 1.02 0.56 4952 23797 all phecode
198 Secondary malignant neoplasm Neoplasms 0.983 0.954 – 1.01 0.267 5801 23481 all phecode
198.1 Secondary malignancy of lymph nodes Neoplasms 0.971 0.937 – 1.01 0.112 3677 21489 all phecode
198.2 Secondary malignancy of respiratory organs Neoplasms 0.985 0.925 – 1.05 0.644 1072 10334 all phecode
198.3
Secondary malignant neoplasm of digestive
Secondary malignant neoplasm of digestive systems
 Neoplasms 0.94 0.875 – 1.01 0.0858 866 8538 all phecode
198.4 Secondary malignant neoplasm of liver Neoplasms 0.981 0.91 – 1.06 0.619 767 7558 all phecode
198.5 Secondary malignancy of brain/spine Neoplasms 0.941 0.867 – 1.02 0.149 640 6338 all phecode
198.6 Secondary malignancy of bone Neoplasms 0.972 0.906 – 1.04 0.437 866 8307 all phecode
198.7 Secondary malignant neoplasm of skin Neoplasms 0.936 0.834 – 1.05 0.264 336 3253 all phecode
199 Neoplasm of uncertain behavior Neoplasms 1.01 0.978 – 1.04 0.601 5693 25767 all phecode
199.4 Neurofibromatosis Neoplasms 1 0.806 – 1.25 0.98 88 880 all phecode
200 Myeloproliferative disease Neoplasms 0.964 0.906 – 1.03 0.248 1113 11098 all phecode
200.1 Polycythemia vera Neoplasms 0.903 0.785 – 1.04 0.15 231 2310 all phecode
201 Hodgkin's disease Neoplasms 1.06 0.909 – 1.24 0.446 172 1705 all phecode
202 Cancer of other lymphoid, histiocytic tissue Neoplasms 0.956 0.907 – 1.01 0.0914 1559 15571 all phecode
202.2 Non-Hodgkins lymphoma Neoplasms 0.918 0.868 – 0.972 0.00316 1329 13268 all phecode
202.21 Nodular lymphoma Neoplasms 0.872 0.807 – 0.943 0.00061 693 6923 all phecode
202.22 Reticulosarcoma Neoplasms 0.934 0.795 – 1.1 0.402 170 1693 all phecode
202.24 Large cell lymphoma Neoplasms 0.863 0.73 – 1.02 0.0838 160 1586 all phecode
204 Leukemia Neoplasms 1 0.926 – 1.08 0.965 689 6876 all phecode
204.1 Lymphoid leukemia Neoplasms 1.03 0.899 – 1.18 0.689 236 2354 all phecode
204.11 Lymphoid leukemia, acute Neoplasms 0.75 0.589 – 0.955 0.0198 74 734 all phecode
204.12 Lymphoid leukemia, chronic Neoplasms 1.12 0.958 – 1.3 0.16 173 1724 all phecode
204.2 Myeloid leukemia Neoplasms 0.975 0.859 – 1.11 0.696 265 2633 all phecode
204.21 Myeloid leukemia, acute Neoplasms 0.996 0.841 – 1.18 0.965 153 1516 all phecode
204.22 Myeloid leukemia, chronic Neoplasms 0.954 0.74 – 1.23 0.715 61 610 all phecode
204.4 Multiple myeloma Neoplasms 0.99 0.861 – 1.14 0.894 217 2162 all phecode
208 Benign neoplasm of colon Neoplasms 1.01 0.992 – 1.04 0.214 10303 34953 all phecode
209 Neuroendocrine tumors Neoplasms 1.1 0.968 – 1.25 0.142 258 2580 all phecode
210 Benign neoplasm of lip, oral cavity, and pharynx Neoplasms 0.982 0.936 – 1.03 0.451 1891 18839 all phecode
211
Benign neoplasm of other parts of digestive
Benign neoplasm of other parts of digestive system
 Neoplasms 1.06 1.03 – 1.09 4.37e-06 7329 36606 all phecode
212
Benign neoplasm of respiratory and
Benign neoplasm of respiratory and intrathoracic organs
 Neoplasms 1.01 0.961 – 1.06 0.727 1843 18412 all phecode
213 Benign neoplasm of bone and articular cartilage Neoplasms 0.985 0.936 – 1.04 0.558 1677 15527 all phecode
214 Lipoma Neoplasms 1.03 0.973 – 1.09 0.331 1437 14132 all phecode
214.1 Lipoma of skin and subcutaneous tissue Neoplasms 1.04 0.973 – 1.12 0.235 883 8710 all phecode
215
Other benign neoplasm of connective and other
Other benign neoplasm of connective and other soft tissue
 Neoplasms 1.02 0.99 – 1.05 0.192 4528 39509 all phecode
216 Benign neoplasm of skin Neoplasms 0.957 0.936 – 0.977 5.41e-05 11528 34919 all phecode
216.1 Screening for malignant neoplasms of the skin Neoplasms 0.884 0.755 – 1.03 0.123 174 1701 all phecode
217 Vascular hamartomas and non-neoplastic nevi Neoplasms 0.921 0.877 – 0.968 0.00119 1786 17184 all phecode
217.1 Nevus, non-neoplastic Neoplasms 0.915 0.869 – 0.963 0.000616 1679 16116 all phecode
218 Benign neoplasm of uterus Neoplasms 1.01 0.977 – 1.05 0.533 4301 16661 all phecode
218.1 Uterine leiomyoma Neoplasms 1.01 0.958 – 1.06 0.791 1835 15733 all phecode
218.2 Other benign neoplasm of uterus Neoplasms 1 0.968 – 1.04 0.802 3403 16447 all phecode
220 Benign neoplasm of ovary Neoplasms 1.01 0.937 – 1.08 0.889 893 8783 all phecode
221 Benign neoplasm of other female genital organs Neoplasms 1.01 0.961 – 1.06 0.766 2042 14248 all phecode
222 Benign neoplasm of male genital organs Neoplasms 1.04 0.974 – 1.1 0.264 1133 10663 all phecode
223
Benign neoplasm of kidney and other urinary
Benign neoplasm of kidney and other urinary organs
 Neoplasms 1.01 0.957 – 1.06 0.785 1801 12657 all phecode
224 Benign neoplasm of eye Neoplasms 0.944 0.873 – 1.02 0.155 691 6752 all phecode
224.1 Benign neoplasm of eye, uveal Neoplasms 0.94 0.863 – 1.02 0.155 595 5773 all phecode
225
Benign neoplasm of brain and other parts of
Benign neoplasm of brain and other parts of nervous system
 Neoplasms 1 0.943 – 1.06 0.974 1209 12074 all phecode
225.1
Benign neoplasm of brain, cranial nerves
Benign neoplasm of brain, cranial nerves, meninges
 Neoplasms 0.986 0.922 – 1.05 0.674 947 9454 all phecode
225.2 Benign neoplasm of spinal cord, meninges Neoplasms 1.08 0.961 – 1.22 0.189 289 2890 all phecode
226 Benign neoplasm of thyroid glands Neoplasms 0.994 0.938 – 1.05 0.826 1329 13264 all phecode
227
Benign neoplasm of other endocrine glands and
Benign neoplasm of other endocrine glands and related structures
 Neoplasms 0.949 0.902 – 0.998 0.0413 1690 16896 all phecode
227.1 Benign neoplasm of adrenal gland Neoplasms 0.994 0.903 – 1.09 0.905 467 4644 all phecode
227.2 Benign neoplasm of parathyroid gland Neoplasms 0.917 0.852 – 0.988 0.0224 795 7941 all phecode
227.3
Benign neoplasm of pituitary gland and
Benign neoplasm of pituitary gland and craniopharyngeal duct (pouch)
 Neoplasms 0.978 0.885 – 1.08 0.663 435 4350 all phecode
228 Hemangioma and lymphangioma, any site Neoplasms 0.955 0.913 – 0.999 0.0444 2149 20946 all phecode
228.1 Hemangioma of skin and subcutaneous tissue Neoplasms 0.962 0.909 – 1.02 0.183 1356 13336 all phecode
229 Benign neoplasm of unspecified sites Neoplasms 0.972 0.948 – 0.996 0.0231 7767 36615 all phecode
229.1 Benign neoplasm of lymph nodes Neoplasms 0.974 0.947 – 1 0.0714 5743 34218 all phecode
240 Simple and unspecified goiter Endocrine/metabolic 0.993 0.93 – 1.06 0.837 1031 9761 all phecode
241 Nontoxic nodular goiter Endocrine/metabolic 1 0.965 – 1.04 0.869 2910 22227 all phecode
241.1 Nontoxic uninodular goiter Endocrine/metabolic 1.01 0.964 – 1.05 0.728 2265 19902 all phecode
241.2 Nontoxic multinodular goiter Endocrine/metabolic 1.03 0.97 – 1.09 0.364 1304 12479 all phecode
242 Thyrotoxicosis with or without goiter Endocrine/metabolic 1.04 0.98 – 1.1 0.212 1400 13425 all phecode
242.1 Graves' disease Endocrine/metabolic 1 0.912 – 1.1 0.984 515 5068 all phecode
242.2 Toxic multinodular goiter Endocrine/metabolic 1 0.833 – 1.21 0.966 124 1224 all phecode
242.3 Exophthalmos Endocrine/metabolic 0.979 0.866 – 1.11 0.73 292 2898 all phecode
242.31 Thyrotoxic exophthalmos Endocrine/metabolic 1.03 0.87 – 1.23 0.699 144 1432 all phecode
244 Hypothyroidism Endocrine/metabolic 1.02 0.993 – 1.04 0.162 8099 32717 all phecode
244.1 Secondary hypothyroidism Endocrine/metabolic 1.02 0.966 – 1.07 0.547 1762 17230 all phecode
244.2 Acquired hypothyroidism Endocrine/metabolic 1.02 0.961 – 1.08 0.525 1261 11982 all phecode
244.4 Hypothyroidism NOS Endocrine/metabolic 1.02 0.99 – 1.04 0.238 7542 32208 all phecode
245 Thyroiditis Endocrine/metabolic 1.01 0.938 – 1.09 0.813 832 7882 all phecode
245.2 Chronic thyroiditis Endocrine/metabolic 1.03 0.947 – 1.11 0.523 686 6517 all phecode
245.21 Chronic lymphocytic thyroiditis Endocrine/metabolic 1.02 0.944 – 1.11 0.568 679 6449 all phecode
246 Other disorders of thyroid Endocrine/metabolic 1.05 1.02 – 1.08 0.00218 6129 30240 all phecode
246.2 Thyroid cyst Endocrine/metabolic 1.12 0.914 – 1.38 0.268 101 960 all phecode
246.7 Abnormal results of function study of thyroid Endocrine/metabolic 0.961 0.896 – 1.03 0.269 886 8696 all phecode
249 Secondary diabetes mellitus Endocrine/metabolic 1.11 1.03 – 1.19 0.00409 1150 8340 all phecode
250 Diabetes mellitus Endocrine/metabolic 1.06 1.03 – 1.08 1.11e-06 13947 31815 all phecode
250.1 Type 1 diabetes Endocrine/metabolic 1.1 1.03 – 1.16 0.00203 2364 11758 all phecode
250.11 Type 1 diabetes with ketoacidosis Endocrine/metabolic 1.26 1.06 – 1.5 0.00768 262 960 all phecode
250.12 Type 1 diabetes with renal manifestations Endocrine/metabolic 1.1 0.977 – 1.23 0.118 551 2686 all phecode
250.13 Type 1 diabetes with ophthalmic manifestations Endocrine/metabolic 1.12 1 – 1.25 0.046 784 3018 all phecode
250.14 Type 1 diabetes with neurological manifestations Endocrine/metabolic 1.12 0.995 – 1.25 0.062 638 2675 all phecode
250.15
Diabetes type 1 with peripheral circulatory
Diabetes type 1 with peripheral circulatory disorders
 Endocrine/metabolic 1.11 0.918 – 1.34 0.285 155 850 all phecode
250.2 Type 2 diabetes Endocrine/metabolic 1.08 1.06 – 1.11 6.18e-10 9843 29688 all phecode
250.21 Type 2 diabetes with ketoacidosis Endocrine/metabolic 1.1 0.943 – 1.28 0.228 282 1327 all phecode
250.22 Type 2 diabetes with renal manifestations Endocrine/metabolic 1.11 1.05 – 1.18 0.000117 1941 13510 all phecode
250.23 Type 2 diabetes with ophthalmic manifestations Endocrine/metabolic 1.09 1.02 – 1.16 0.0111 1643 9668 all phecode
250.24 Type 2 diabetes with neurological manifestations Endocrine/metabolic 1.16 1.1 – 1.22 6.74e-09 2557 16502 all phecode
250.25
Diabetes type 2 with peripheral circulatory
Diabetes type 2 with peripheral circulatory disorders
 Endocrine/metabolic 1.05 0.971 – 1.14 0.219 860 6143 all phecode
250.3 Insulin pump user Endocrine/metabolic 1.1 1.05 – 1.15 1.57e-05 3496 20809 all phecode
250.4 Abnormal glucose Endocrine/metabolic 1.02 0.997 – 1.05 0.0812 8385 30645 all phecode
250.41 Impaired fasting glucose Endocrine/metabolic 1.01 0.963 – 1.07 0.622 1870 15861 all phecode
250.42 Other abnormal glucose Endocrine/metabolic 1.03 0.998 – 1.06 0.0646 7553 30071 all phecode
250.5 Glycosuria or Acetonuria Endocrine/metabolic 1.14 0.948 – 1.37 0.164 136 1067 all phecode
250.6 Polyneuropathy in diabetes Endocrine/metabolic 1.15 1.09 – 1.22 4.38e-07 2132 13390 all phecode
250.7 Diabetic retinopathy Endocrine/metabolic 1.04 0.988 – 1.1 0.127 1691 10517 all phecode
251 Other disorders of pancreatic internal secretion Endocrine/metabolic 1.08 1.01 – 1.15 0.0249 991 8469 all phecode
251.1 Hypoglycemia Endocrine/metabolic 1.13 1.05 – 1.21 0.000716 1207 8570 all phecode
252 Disorders of parathyroid gland Endocrine/metabolic 1.01 0.964 – 1.05 0.752 2282 22119 all phecode
252.1 Hyperparathyroidism Endocrine/metabolic 1.01 0.965 – 1.06 0.661 2088 20335 all phecode
252.2 Hypoparathyroidism Endocrine/metabolic 0.994 0.905 – 1.09 0.908 508 5073 all phecode
253
Disorders of the pituitary gland and its
Disorders of the pituitary gland and its hypothalamic control
 Endocrine/metabolic 1.01 0.938 – 1.08 0.823 859 8544 all phecode
253.1 Pituitary hyperfunction Endocrine/metabolic 0.936 0.825 – 1.06 0.31 263 2621 all phecode
253.11 Acromegaly and gigantism Endocrine/metabolic 0.937 0.75 – 1.17 0.564 83 826 all phecode
253.2 Pituitary hypofunction Endocrine/metabolic 1.16 1.01 – 1.33 0.0419 226 2250 all phecode
253.3 Diabetes insipidus Endocrine/metabolic 1.06 0.852 – 1.33 0.586 86 860 all phecode
253.4 Anterior pituitary disorders Endocrine/metabolic 1.07 0.884 – 1.3 0.481 121 1209 all phecode
253.7 Other disorders of neurohypophysis Endocrine/metabolic 1.04 0.849 – 1.27 0.706 108 1080 all phecode
255 Disorders of adrenal glands Endocrine/metabolic 1.03 0.98 – 1.09 0.226 1506 14869 all phecode
255.1 Adrenal hyperfunction Endocrine/metabolic 0.971 0.872 – 1.08 0.593 373 3730 all phecode
255.11 Cushing's syndrome Endocrine/metabolic 0.953 0.821 – 1.11 0.534 183 1830 all phecode
255.12 Hyperaldosteronism Endocrine/metabolic 0.92 0.766 – 1.1 0.369 135 1350 all phecode
255.2 Adrenal hypofunction Endocrine/metabolic 1.02 0.939 – 1.11 0.647 626 6239 all phecode
255.21 Glucocorticoid deficiency Endocrine/metabolic 1 0.924 – 1.09 0.91 596 5941 all phecode
256 Ovarian dysfunction Endocrine/metabolic 0.974 0.915 – 1.04 0.395 1146 10513 all phecode
256.4 Polycystic ovaries Endocrine/metabolic 1.01 0.94 – 1.09 0.711 742 7128 all phecode
257 Testicular dysfunction Endocrine/metabolic 1 0.94 – 1.07 0.888 1015 9238 all phecode
257.1 Testicular hypofunction Endocrine/metabolic 1.01 0.94 – 1.08 0.865 983 8933 all phecode
258 Iatrogenic endocrine disorders Endocrine/metabolic 1.33 1.06 – 1.67 0.014 91 910 all phecode
258.1 Postablative ovarian failure Endocrine/metabolic 0.889 0.732 – 1.08 0.235 109 1090 all phecode
259 Other endocrine disorders Endocrine/metabolic 1.03 0.963 – 1.1 0.42 1038 10259 all phecode
260 Protein-calorie malnutrition Endocrine/metabolic 1.06 1.01 – 1.1 0.0067 2880 26812 all phecode
260.1 Cachexia Endocrine/metabolic 1.05 0.93 – 1.19 0.43 292 2911 all phecode
260.2 severe protein-calorie malnutrition Endocrine/metabolic 1.04 0.988 – 1.09 0.135 1691 16847 all phecode
260.22 Nutritional marasmus Endocrine/metabolic 1.03 0.945 – 1.12 0.526 614 6140 all phecode
260.3 Adult failure to thrive Endocrine/metabolic 1.08 0.992 – 1.17 0.0786 629 6236 all phecode
260.6 Anorexia Endocrine/metabolic 1.05 0.981 – 1.13 0.154 868 8591 all phecode
260.7 Polyphagia Endocrine/metabolic 1.08 0.839 – 1.38 0.565 65 643 all phecode
261 Vitamin deficiency Endocrine/metabolic 1 0.98 – 1.03 0.702 7718 35203 all phecode
261.1 Vitamin A deficiency Endocrine/metabolic 1.15 0.903 – 1.47 0.254 69 690 all phecode
261.2 Vitamin B-complex deficiencies Endocrine/metabolic 0.986 0.918 – 1.06 0.707 857 8405 all phecode
261.4 Vitamin D deficiency Endocrine/metabolic 1.01 0.984 – 1.04 0.446 7255 35225 all phecode
261.41 Rickets or osteomalacia Endocrine/metabolic 1.06 0.801 – 1.41 0.68 52 511 all phecode
262 Mineral deficiency NEC Endocrine/metabolic 1.04 0.978 – 1.1 0.213 1182 11676 all phecode
263 Other nutritional deficiency Endocrine/metabolic 1.01 0.956 – 1.06 0.8 1651 15788 all phecode
264 Lack of normal physiological development Endocrine/metabolic 0.906 0.793 – 1.04 0.147 239 2301 all phecode
264.2 Failure to thrive (childhood) Endocrine/metabolic 0.945 0.782 – 1.14 0.561 122 1220 all phecode
264.9
Lack of normal physiological development
Lack of normal physiological development, unspecified
 Endocrine/metabolic 0.805 0.64 – 1.01 0.0638 81 772 all phecode
269 Proteinuria Endocrine/metabolic 1.02 0.968 – 1.07 0.482 1694 13981 all phecode
270
Disorders of protein plasma/amino-acid
Disorders of protein plasma/amino-acid transport and metabolism
 Endocrine/metabolic 1 0.936 – 1.07 0.983 967 9575 all phecode
270.1 Disturbances of amino-acid transport Endocrine/metabolic 0.995 0.85 – 1.17 0.953 170 1697 all phecode
270.11
Disturbances of sulphur-bearing amino-acid
Disturbances of sulphur-bearing amino-acid metabolism
 Endocrine/metabolic 0.931 0.778 – 1.12 0.441 134 1334 all phecode
270.2 Disorders of amino-acid metabolism Endocrine/metabolic 1.18 0.963 – 1.45 0.11 96 954 all phecode
270.3 Disorders of plasma protein metabolism Endocrine/metabolic 0.998 0.925 – 1.08 0.955 737 7303 all phecode
270.32 Paraproteinemia Endocrine/metabolic 1.02 0.916 – 1.13 0.746 384 3781 all phecode
270.33 Amyloidosis Endocrine/metabolic 1 0.782 – 1.28 0.997 71 695 all phecode
270.34 Alpha-1-antitrypsin deficiency Endocrine/metabolic 1 0.783 – 1.28 0.991 69 690 all phecode
270.38
Other specified disorders of plasma protein
Other specified disorders of plasma protein metabolism
 Endocrine/metabolic 1.02 0.907 – 1.15 0.718 299 2984 all phecode
271
Disorders of carbohydrate transport and
Disorders of carbohydrate transport and metabolism
 Endocrine/metabolic 0.995 0.958 – 1.03 0.818 2907 28132 all phecode
271.3
Intestinal disaccharidase deficiencies and
Intestinal disaccharidase deficiencies and disaccharide malabsorption
 Endocrine/metabolic 0.994 0.956 – 1.03 0.758 2827 27425 all phecode
271.9
Other disorders of carbohydrate transport and
Other disorders of carbohydrate transport and metabolism
 Endocrine/metabolic 1.02 0.825 – 1.25 0.873 102 1007 all phecode
272 Disorders of lipoid metabolism Endocrine/metabolic 1.01 0.994 – 1.04 0.175 18881 26670 all phecode
272.1 Hyperlipidemia Endocrine/metabolic 1.01 0.993 – 1.04 0.187 18843 26654 all phecode
272.11 Hypercholesterolemia Endocrine/metabolic 1.01 0.976 – 1.04 0.661 5928 21600 all phecode
272.12 Hyperglyceridemia Endocrine/metabolic 1 0.944 – 1.06 0.992 1360 11837 all phecode
272.13 Mixed hyperlipidemia Endocrine/metabolic 1.04 1 – 1.08 0.0501 3538 18449 all phecode
272.9 Unspecified disorder of lipoid metabolism Endocrine/metabolic 1.08 0.963 – 1.22 0.185 313 3011 all phecode
274 Gout and other crystal arthropathies Endocrine/metabolic 1.01 0.973 – 1.06 0.518 2524 22729 all phecode
274.1 Gout Endocrine/metabolic 1.01 0.973 – 1.06 0.499 2409 21991 all phecode
274.11 Gouty arthropathy Endocrine/metabolic 0.98 0.919 – 1.04 0.53 1082 10576 all phecode
274.2 Crystal arthropathies Endocrine/metabolic 0.987 0.853 – 1.14 0.86 195 1890 all phecode
274.21 Chondrocalcinosis Endocrine/metabolic 0.983 0.845 – 1.14 0.819 183 1772 all phecode
275 Disorders of mineral metabolism Endocrine/metabolic 1.02 0.986 – 1.05 0.268 4357 37091 all phecode
275.1 Disorders of iron metabolism Hematopoietic 1.1 0.962 – 1.26 0.161 218 2180 all phecode
275.11 Hereditary hemochromatosis Hematopoietic 1.12 0.913 – 1.38 0.274 99 990 all phecode
275.2 Disorders of copper metabolism Endocrine/metabolic 1.08 0.833 – 1.39 0.575 62 614 all phecode
275.3 Disorders of magnesium metabolism Endocrine/metabolic 1.04 0.981 – 1.11 0.179 1154 11504 all phecode
275.5 Disorders of calcium/phosphorus metabolism Endocrine/metabolic 0.998 0.963 – 1.03 0.919 3369 31544 all phecode
275.51 Hypocalcemia Endocrine/metabolic 0.972 0.906 – 1.04 0.421 898 8969 all phecode
275.53 Disorders of phosphorus metabolism Endocrine/metabolic 1.05 0.995 – 1.11 0.0729 1366 13634 all phecode
275.6 Hypercalcemia Endocrine/metabolic 0.96 0.909 – 1.01 0.148 1468 14183 all phecode
276
Disorders of fluid, electrolyte, and acid-base
Disorders of fluid, electrolyte, and acid-base balance
 Endocrine/metabolic 1.02 0.999 – 1.05 0.0637 9238 37046 all phecode
276.1 Electrolyte imbalance Endocrine/metabolic 1.02 0.988 – 1.04 0.262 6352 34366 all phecode
276.11 Hyperosmolality and/or hypernatremia Endocrine/metabolic 0.912 0.833 – 0.998 0.0448 550 5434 all phecode
276.12 Hyposmolality and/or hyponatremia Endocrine/metabolic 1.03 0.991 – 1.08 0.124 2514 23219 all phecode
276.13 Hyperpotassemia Endocrine/metabolic 1.02 0.98 – 1.06 0.351 2992 25216 all phecode
276.14 Hypopotassemia Endocrine/metabolic 1.02 0.979 – 1.07 0.295 2148 20909 all phecode
276.4 Acid-base balance disorder Endocrine/metabolic 1.05 1 – 1.1 0.0352 2086 20332 all phecode
276.41 Acidosis Endocrine/metabolic 1.06 1.01 – 1.12 0.0153 1788 17572 all phecode
276.42 Alkalosis Endocrine/metabolic 1.03 0.935 – 1.13 0.571 476 4741 all phecode
276.5 Hypovolemia Endocrine/metabolic 1.03 1 – 1.06 0.048 4574 34527 all phecode
276.6 Fluid overload Endocrine/metabolic 1.02 0.961 – 1.08 0.564 1384 13211 all phecode
276.8 Polydipsia Endocrine/metabolic 1.09 0.902 – 1.31 0.376 124 1240 all phecode
277 Other disorders of metabolism Endocrine/metabolic 1.01 0.979 – 1.05 0.5 4112 35070 all phecode
277.2
Other disorders of purine and pyrimidine
Other disorders of purine and pyrimidine metabolism
 Endocrine/metabolic 0.994 0.897 – 1.1 0.912 403 3991 all phecode
277.4 Disorders of bilirubin excretion Endocrine/metabolic 1 0.93 – 1.09 0.901 720 7161 all phecode
277.5 Other disorders of lipoid metabolism Endocrine/metabolic 0.997 0.932 – 1.07 0.925 936 9270 all phecode
277.51 Lipoprotein disorders Endocrine/metabolic 1 0.933 – 1.08 0.903 773 7668 all phecode
277.7 Dysmetabolic syndrome X Endocrine/metabolic 1 0.937 – 1.08 0.903 916 8359 all phecode
278 Overweight, obesity and other hyperalimentation Endocrine/metabolic 1.06 1.04 – 1.08 1.78e-09 19419 27331 all phecode
278.1 Obesity Endocrine/metabolic 1.06 1.04 – 1.08 6.65e-10 17129 27321 all phecode
278.11 Morbid obesity Endocrine/metabolic 1.08 1.05 – 1.11 4.29e-09 8280 27172 all phecode
278.3 Localized adiposity Endocrine/metabolic 1.11 0.992 – 1.25 0.0677 324 3228 all phecode
278.4 Abnormal weight gain Endocrine/metabolic 1.07 1.02 – 1.12 0.00269 2104 17411 all phecode
279 Disorders involving the immune mechanism Endocrine/metabolic 1.02 0.986 – 1.07 0.208 2934 28612 all phecode
279.1 Immunity deficiency Endocrine/metabolic 1.04 0.977 – 1.1 0.223 1161 11571 all phecode
279.11 Deficiency of humoral immunity Endocrine/metabolic 0.959 0.856 – 1.07 0.465 330 3278 all phecode
279.2 Autoimmune disease NEC Endocrine/metabolic 1.12 1.04 – 1.21 0.00333 754 7516 all phecode
279.7 Other immunological findings Endocrine/metabolic 1.02 0.991 – 1.05 0.167 4885 36552 all phecode
279.8
Other specified disorders involving the immune
Other specified disorders involving the immune mechanism
 Endocrine/metabolic 1.1 1.01 – 1.2 0.0218 601 5988 all phecode
280 Iron deficiency anemias Hematopoietic 1.03 1 – 1.06 0.0519 4626 30873 all phecode
280.1
Iron deficiency anemias, unspecified or not due
Iron deficiency anemias, unspecified or not due to blood loss
 Hematopoietic 1.03 0.997 – 1.06 0.0734 4484 30649 all phecode
280.2
Iron deficiency anemia secondary to blood loss
Iron deficiency anemia secondary to blood loss (chronic)
 Hematopoietic 1.02 0.97 – 1.07 0.444 1771 17196 all phecode
281 Other deficiency anemia Hematopoietic 0.931 0.849 – 1.02 0.134 519 5120 all phecode
281.1 Megaloblastic anemia Hematopoietic 0.926 0.81 – 1.06 0.258 253 2497 all phecode
281.11 Pernicious anemia Hematopoietic 0.85 0.7 – 1.03 0.101 114 1108 all phecode
281.12 Other vitamin B12 deficiency anemia Hematopoietic 0.958 0.819 – 1.12 0.591 187 1817 all phecode
281.9 Deficiency anemias Hematopoietic 0.92 0.812 – 1.04 0.19 285 2830 all phecode
282 Hereditary hemolytic anemias Hematopoietic 1.07 0.957 – 1.21 0.223 323 3188 all phecode
282.8 Other hemoglobinopathies Hematopoietic 1.15 0.998 – 1.32 0.0532 216 2113 all phecode
282.9 Other hereditary hemolytic anemias Hematopoietic 1.06 0.912 – 1.24 0.438 192 1920 all phecode
283 Acquired hemolytic anemias Hematopoietic 0.987 0.832 – 1.17 0.881 155 1550 all phecode
283.1 Autoimmune hemolytic anemias Hematopoietic 1.19 0.918 – 1.55 0.187 64 633 all phecode
284 Aplastic anemia Hematopoietic 0.92 0.851 – 0.995 0.0381 697 6943 all phecode
284.1 Pancytopenia Hematopoietic 0.921 0.847 – 1 0.0548 612 6100 all phecode
285 Other anemias Hematopoietic 1.03 1.01 – 1.06 0.00209 11794 33591 all phecode
285.1 Acute posthemorrhagic anemia Hematopoietic 1.03 0.989 – 1.06 0.175 3325 27709 all phecode
285.2 Anemia of chronic disease Hematopoietic 1.03 0.989 – 1.08 0.143 2055 19939 all phecode
285.21 Anemia in chronic kidney disease Hematopoietic 1 0.938 – 1.08 0.89 932 9106 all phecode
285.22 Anemia in neoplastic disease Hematopoietic 0.984 0.909 – 1.07 0.702 690 6892 all phecode
286 Coagulation defects Hematopoietic 1.03 0.994 – 1.06 0.102 3844 33384 all phecode
286.1 Congenital coagulation defects Hematopoietic 0.917 0.805 – 1.04 0.188 250 2466 all phecode
286.11 Von willebrand's disease Hematopoietic 0.981 0.785 – 1.23 0.87 83 822 all phecode
286.12
Congenital deficiency of other clotting factors
Congenital deficiency of other clotting factors (including factor VII)
 Hematopoietic 0.873 0.728 – 1.05 0.146 126 1260 all phecode
286.2
Encounter for long-term (current) use of
Encounter for long-term (current) use of anticoagulants
 Hematopoietic 1.02 0.981 – 1.06 0.362 3354 25918 all phecode
286.3
Coagulation defects complicating pregnancy or
Coagulation defects complicating pregnancy or postpartum
 Hematopoietic 1.04 0.844 – 1.28 0.707 97 962 all phecode
286.4 Acquired coagulation factor deficiency Hematopoietic 1.1 0.962 – 1.26 0.165 254 2529 all phecode
286.5
Hemorrhagic disorder due to intrinsic
Hemorrhagic disorder due to intrinsic circulating anticoagulants
 Hematopoietic 1.04 0.866 – 1.25 0.679 132 1294 all phecode
286.6 Defibrination syndrome Hematopoietic 1.03 0.993 – 1.08 0.104 2579 25377 all phecode
286.7 Other and unspecified coagulation defects Hematopoietic 1.03 0.994 – 1.07 0.101 3014 29294 all phecode
286.8 Hypercoagulable state Hematopoietic 0.988 0.92 – 1.06 0.747 846 8437 all phecode
286.81 Primary hypercoagulable state Hematopoietic 0.987 0.917 – 1.06 0.72 813 8111 all phecode
286.9 Abnormal coagulation profile Hematopoietic 1.06 0.999 – 1.13 0.0523 1182 11487 all phecode
287 Purpura and other hemorrhagic conditions Hematopoietic 0.999 0.963 – 1.04 0.958 3288 28474 all phecode
287.1 Spontaneous ecchymoses Hematopoietic 0.927 0.803 – 1.07 0.297 211 2094 all phecode
287.3 Thrombocytopenia Hematopoietic 1 0.962 – 1.04 0.996 2938 26323 all phecode
287.31 Primary thrombocytopenia Hematopoietic 1.01 0.93 – 1.1 0.773 601 5994 all phecode
287.32 Secondary thrombocytopenia Hematopoietic 0.941 0.862 – 1.03 0.175 569 5686 all phecode
287.4 Qualitative platelet defects Hematopoietic 1.09 0.894 – 1.32 0.405 112 1120 all phecode
288 Diseases of white blood cells Hematopoietic 1.03 0.999 – 1.06 0.0564 4886 36527 all phecode
288.1 Decreased white blood cell count Hematopoietic 0.976 0.926 – 1.03 0.365 1599 15951 all phecode
288.11 Neutropenia Hematopoietic 0.962 0.903 – 1.02 0.225 1106 11041 all phecode
288.2 Elevated white blood cell count Hematopoietic 1.04 1.01 – 1.08 0.0129 4082 35079 all phecode
288.3 Eosinophilia Hematopoietic 0.954 0.821 – 1.11 0.538 187 1866 all phecode
289 Other diseases of blood and blood-forming organs Hematopoietic 1.03 0.98 – 1.08 0.239 1757 17434 all phecode
289.3
Personal history of diseases of blood and
Personal history of diseases of blood and blood-forming organs
 Hematopoietic 1.05 0.979 – 1.12 0.175 918 9087 all phecode
289.4 Lymphadenitis Hematopoietic 0.975 0.943 – 1.01 0.136 3888 34715 all phecode
289.5 Diseases of spleen Hematopoietic 0.921 0.828 – 1.02 0.128 393 3913 all phecode
289.8 Polycythemia, secondary Hematopoietic 0.927 0.813 – 1.06 0.26 255 2550 all phecode
289.9 Abnormality of red blood cells Hematopoietic 1.03 0.928 – 1.15 0.566 385 3813 all phecode
290
Delirium dementia and amnestic and other
Delirium dementia and amnestic and other cognitive disorders
 Mental Disorders 1.04 0.978 – 1.1 0.233 1318 11547 all phecode
290.1 Dementias Mental Disorders 0.936 0.855 – 1.02 0.148 541 4910 all phecode
290.11 Alzheimer's disease Mental Disorders 0.898 0.761 – 1.06 0.205 151 1389 all phecode
290.12 Dementia with cerebral degenerations Mental Disorders 0.896 0.724 – 1.11 0.314 88 846 all phecode
290.13 Senile dementia Mental Disorders 0.94 0.839 – 1.05 0.284 340 3078 all phecode
290.16 Vascular dementia Mental Disorders 1.04 0.821 – 1.32 0.743 81 777 all phecode
290.2 Delirium due to conditions classified elsewhere Mental Disorders 1.1 1.02 – 1.19 0.0142 750 7358 all phecode
290.3
Other persistent mental disorders due to
Other persistent mental disorders due to conditions classified elsewhere
 Mental Disorders 0.989 0.922 – 1.06 0.766 886 8618 all phecode
291
Other specified nonpsychotic and/or transient
Other specified nonpsychotic and/or transient mental disorders
 Mental Disorders 1.03 0.991 – 1.08 0.125 2550 24810 all phecode
291.1
Transient mental disorders due to conditions
Transient mental disorders due to conditions classified elsewhere
 Mental Disorders 0.929 0.795 – 1.09 0.355 175 1750 all phecode
291.4
Specific nonpsychotic mental disorders due to
Specific nonpsychotic mental disorders due to brain damage
 Mental Disorders 0.987 0.898 – 1.09 0.795 484 4807 all phecode
291.8 Alteration of consciousness Mental Disorders 1.05 1 – 1.1 0.0437 2036 19974 all phecode
292 Neurological disorders Mental Disorders 1.01 0.982 – 1.04 0.463 5733 38553 all phecode
292.1 Aphasia/speech disturbance Mental Disorders 0.943 0.9 – 0.988 0.0134 2013 19867 all phecode
292.11 Aphasia Mental Disorders 0.895 0.826 – 0.97 0.00719 664 6581 all phecode
292.12 Symbolic dysfunction Mental Disorders 0.81 0.697 – 0.94 0.0055 200 1988 all phecode
292.2 Mild cognitive impairment Mental Disorders 1.01 0.913 – 1.13 0.788 389 3731 all phecode
292.3 Memory loss Mental Disorders 1.01 0.961 – 1.06 0.753 1922 18158 all phecode
292.4 Altered mental status Mental Disorders 1.04 0.999 – 1.09 0.0561 2454 22725 all phecode
292.5 Transient alteration of awareness Mental Disorders 0.969 0.878 – 1.07 0.535 430 4285 all phecode
292.6 Hallucinations Mental Disorders 1.01 0.877 – 1.16 0.923 217 2147 all phecode
293 Symptoms involving head and neck Mental Disorders 0.94 0.848 – 1.04 0.237 414 4127 all phecode
293.1
Swelling, mass, or lump in head and neck
Swelling, mass, or lump in head and neck [Space-occupying lesion, intracranial NOS]
 Mental Disorders 0.982 0.952 – 1.01 0.271 4417 38609 all phecode
295 Schizophrenia and other psychotic disorders Mental Disorders 1.08 1.01 – 1.16 0.0256 885 8229 all phecode
295.1 Schizophrenia Mental Disorders 1.11 0.93 – 1.33 0.244 138 1339 all phecode
295.2 Paranoid disorders Mental Disorders 1.31 1.07 – 1.6 0.00822 118 1079 all phecode
295.3 Psychosis Mental Disorders 1.06 0.98 – 1.15 0.144 716 6694 all phecode
296 Mood disorders Mental Disorders 1.09 1.06 – 1.11 3.48e-14 15356 20858 all phecode
296.1 Bipolar Mental Disorders 1.11 1.05 – 1.18 0.000393 1301 11264 all phecode
296.2 Depression Mental Disorders 1.09 1.07 – 1.11 7.3e-15 14833 20856 all phecode
296.22 Major depressive disorder Mental Disorders 1.09 1.07 – 1.12 2.96e-14 13850 20853 all phecode
297 Suicidal ideation or attempt Mental Disorders 1.07 1 – 1.15 0.0454 985 9050 all phecode
297.1 Suicidal ideation Mental Disorders 1.1 1.02 – 1.19 0.0128 788 7310 all phecode
297.2 Suicide or self-inflicted injury Mental Disorders 1.2 1.06 – 1.36 0.00323 285 2654 all phecode
300 Anxiety disorders Mental Disorders 1.08 1.06 – 1.11 2.7e-13 15419 20850 all phecode
300.1 Anxiety disorder Mental Disorders 1.08 1.06 – 1.11 1.53e-12 14517 20855 all phecode
300.11 Generalized anxiety disorder Mental Disorders 1.11 1.08 – 1.15 6e-11 5546 20512 all phecode
300.12 Agorophobia, social phobia, and panic disorder Mental Disorders 1.08 1.02 – 1.15 0.0117 1360 11377 all phecode
300.13 Phobia Mental Disorders 1.1 1.03 – 1.17 0.00572 1051 9542 all phecode
300.3 Obsessive-compulsive disorders Mental Disorders 1.15 1.02 – 1.29 0.0226 328 3018 all phecode
300.4 Dysthymic disorder Mental Disorders 1.09 1.04 – 1.14 0.000111 2420 16552 all phecode
300.8 Acute reaction to stress Mental Disorders 1.14 1.04 – 1.25 0.00638 504 4825 all phecode
300.9 Posttraumatic stress disorder Mental Disorders 1.18 1.09 – 1.27 1.19e-05 843 7909 all phecode
301 Personality disorders Mental Disorders 1.15 1.04 – 1.26 0.0052 477 4539 all phecode
301.2 Antisocial/borderline personality disorder Mental Disorders 1.14 1 – 1.3 0.0455 254 2393 all phecode
302 Sexual and gender identity disorders Mental Disorders 1.03 0.989 – 1.07 0.173 3700 13808 all phecode
302.1 Decreased libido Mental Disorders 1 0.906 – 1.11 0.976 447 4331 all phecode
303 Psychogenic and somatoform disorders Mental Disorders 1.01 0.982 – 1.04 0.479 6808 20043 all phecode
303.1 Dissociative disorder Mental Disorders 1.2 1.02 – 1.41 0.0271 161 1573 all phecode
303.3 Psychogenic disorder Mental Disorders 1 0.973 – 1.03 0.901 6487 19888 all phecode
303.31
Gastrointestinal malfunction arising from
Gastrointestinal malfunction arising from mental factors
 Mental Disorders 1.04 0.939 – 1.14 0.472 471 4623 all phecode
303.4 Somatoform disorder Mental Disorders 1.09 1.02 – 1.16 0.00883 1177 11180 all phecode
304 Adjustment reaction Mental Disorders 1.03 0.992 – 1.06 0.134 3888 20475 all phecode
305.2 Eating disorder Mental Disorders 1.13 1.05 – 1.21 0.000929 901 8329 all phecode
306 Other mental disorder Mental Disorders 1.05 0.996 – 1.1 0.0718 1815 14133 all phecode
306.1 Mental disorders durring/after pregnancy Mental Disorders 1.05 0.956 – 1.15 0.327 587 3527 all phecode
306.9 Tension headache Mental Disorders 1.07 0.987 – 1.15 0.105 753 7277 all phecode
312 Conduct disorders Mental Disorders 1.15 1.01 – 1.31 0.0308 254 2501 all phecode
312.3 Impulse control disorder Mental Disorders 1.43 1.13 – 1.82 0.00293 74 736 all phecode
313 Pervasive developmental disorders Mental Disorders 1.07 1.02 – 1.13 0.0095 1571 14633 all phecode
313.1 Attention deficit hyperactivity disorder Mental Disorders 1.08 1.02 – 1.14 0.00796 1392 13190 all phecode
313.2 Tics and stuttering Mental Disorders 1.11 0.872 – 1.42 0.395 77 770 all phecode
313.3 Autism Mental Disorders 0.857 0.668 – 1.1 0.227 64 621 all phecode
315 Develomental delays and disorders Mental Disorders 1.01 0.93 – 1.09 0.868 684 6788 all phecode
315.1 Learning disorder Mental Disorders 1.13 0.911 – 1.41 0.26 87 860 all phecode
315.2 Speech and language disorder Mental Disorders 0.929 0.816 – 1.06 0.262 254 2539 all phecode
316 Substance addiction and disorders Mental Disorders 1.12 1.08 – 1.15 6.33e-10 3682 32680 all phecode
316.1 Polyneuropathy due to drugs Mental Disorders 0.984 0.906 – 1.07 0.708 634 6331 all phecode
317 Alcohol-related disorders Mental Disorders 1.06 1.02 – 1.11 0.00378 2525 22920 all phecode
317.1 Alcoholism Mental Disorders 1.08 1.03 – 1.13 0.000994 1986 19339 all phecode
317.11 Alcoholic liver damage Mental Disorders 1.06 0.961 – 1.18 0.235 408 4080 all phecode
318 Tobacco use disorder Mental Disorders 1.11 1.09 – 1.14 3.64e-18 8622 34842 all phecode
320 Meningitis Neurological 0.924 0.833 – 1.02 0.134 382 3820 all phecode
323 Encephalitis Neurological 1.05 0.898 – 1.22 0.558 181 1809 all phecode
323.8 Encephalitis, non-infectious Neurological 0.967 0.818 – 1.14 0.693 153 1527 all phecode
324 Other CNS infection and poliomyelitis Neurological 1.01 0.896 – 1.14 0.847 288 2880 all phecode
325
Phlebitis and thrombophlebitis of intracranial
Phlebitis and thrombophlebitis of intracranial venous sinuses
 Neurological 1.12 0.842 – 1.49 0.434 53 530 all phecode
327 Sleep disorders Neurological 1.05 1.03 – 1.07 3.89e-07 14941 31602 all phecode
327.1 Hypersomnia Neurological 1.01 0.967 – 1.06 0.599 2061 19110 all phecode
327.3 Sleep apnea Neurological 1.04 1.02 – 1.06 0.000525 10909 31304 all phecode
327.31 Central/nonobstroctive sleep apnea Neurological 1.01 0.922 – 1.11 0.782 492 4784 all phecode
327.32 Obstructive sleep apnea Neurological 1.04 1.02 – 1.07 0.000606 8744 30530 all phecode
327.4 Insomnia Neurological 1.08 1.05 – 1.11 1.42e-07 5524 30960 all phecode
327.41 Organic or persistent insomnia Neurological 1.04 0.982 – 1.1 0.172 1265 12120 all phecode
327.5 Parasomnia Neurological 1.04 0.955 – 1.13 0.368 604 5913 all phecode
327.6 Circadian rhythm sleep disorder Neurological 0.967 0.853 – 1.1 0.602 274 2666 all phecode
327.7 Sleep related movement disorders Neurological 1.14 1.09 – 1.2 1.9e-07 1786 17323 all phecode
327.71 Restless legs syndrome Neurological 1.17 1.11 – 1.24 3.68e-09 1570 15360 all phecode
327.72 Sleep related leg cramps Neurological 1.03 0.827 – 1.28 0.796 83 822 all phecode
331 Other cerebral degenerations Neurological 0.981 0.908 – 1.06 0.633 717 7024 all phecode
331.1 Hydrocephalus Neurological 0.929 0.822 – 1.05 0.234 284 2836 all phecode
331.9 Cerebral degeneration, unspecified Neurological 0.974 0.878 – 1.08 0.617 419 4026 all phecode
332 Parkinson's disease Neurological 0.977 0.882 – 1.08 0.659 415 4128 all phecode
333
Extrapyramidal disease and abnormal movement
Extrapyramidal disease and abnormal movement disorders
 Neurological 1.1 1.06 – 1.14 1.88e-06 2868 26583 all phecode
333.1 Essential tremor Neurological 1.06 0.978 – 1.14 0.162 725 7163 all phecode
333.2 Myoclonus Neurological 1.01 0.855 – 1.18 0.943 159 1590 all phecode
333.4 Torsion dystonia Neurological 0.981 0.878 – 1.1 0.735 352 3504 all phecode
333.8 Other degenerative diseases of the basal ganglia Neurological 1 0.804 – 1.25 0.997 89 890 all phecode
334 Degenerative disease of the spinal cord Neurological 0.983 0.922 – 1.05 0.6 1058 10562 all phecode
334.1 Spinocerebellar disease Neurological 0.985 0.787 – 1.23 0.896 79 790 all phecode
334.2 Anterior horn cell disease Neurological 0.967 0.799 – 1.17 0.731 110 1080 all phecode
334.21 Amyotrophic Lateral Sclerosis Neurological 1.08 0.847 – 1.37 0.548 71 693 all phecode
335 Multiple sclerosis Neurological 0.941 0.848 – 1.05 0.258 396 3951 all phecode
337 Disorders of the autonomic nervous system Neurological 1.08 1.01 – 1.16 0.0334 808 7413 all phecode
337.1 Peripheral autonomic neuropathy Neurological 1.1 0.988 – 1.22 0.0828 370 3164 all phecode
338 Pain Neurological 1.05 1.03 – 1.07 9.21e-08 20346 26417 all phecode
338.1 Acute pain Neurological 1.04 1.02 – 1.06 9.51e-05 15582 26313 all phecode
338.2 Chronic pain Neurological 1.09 1.07 – 1.12 2.22e-14 10994 26368 all phecode
339 Other headache syndromes Neurological 1.07 1.05 – 1.1 6.67e-09 9242 34658 all phecode
340 Migraine Neurological 1.08 1.05 – 1.11 4.69e-08 6708 30587 all phecode
340.1 Migrain with aura Neurological 1.07 1.03 – 1.11 0.000136 3624 23684 all phecode
341
Other demyelinating diseases of central nervous
Other demyelinating diseases of central nervous system
 Neurological 0.94 0.784 – 1.13 0.508 133 1330 all phecode
342 Hemiplegia Neurological 0.991 0.899 – 1.09 0.847 464 4607 all phecode
343 Infantile cerebral palsy Neurological 0.977 0.769 – 1.24 0.847 85 847 all phecode
344 Other paralytic syndromes Neurological 0.977 0.902 – 1.06 0.568 682 6808 all phecode
345 Epilepsy, recurrent seizures, convulsions Neurological 1.04 0.999 – 1.08 0.054 2553 25307 all phecode
345.1 Epilepsy Neurological 0.988 0.916 – 1.07 0.752 747 7465 all phecode
345.11 Generalized convulsive epilepsy Neurological 0.949 0.831 – 1.09 0.447 233 2330 all phecode
345.12 Partial epilepsy Neurological 0.98 0.895 – 1.07 0.657 534 5335 all phecode
345.3 Convulsions Neurological 1.04 0.994 – 1.08 0.0892 2396 23796 all phecode
346
Abnormal findings on study of brain and/or
Abnormal findings on study of brain and/or nervous system
 Neurological 0.986 0.848 – 1.15 0.855 183 1824 all phecode
346.1
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of skull and head
 Neurological 0.996 0.944 – 1.05 0.895 1472 14587 all phecode
346.2
Nonspecific abnormal results of function study
Nonspecific abnormal results of function study of brain and central nervous system
 Neurological 0.937 0.778 – 1.13 0.498 120 1181 all phecode
346.3
Nonspecific abnormal findings in cerebrospinal
Nonspecific abnormal findings in cerebrospinal fluid
 Neurological 1.14 0.944 – 1.38 0.174 110 1100 all phecode
347 Cataplexy and narcolepsy Neurological 0.94 0.772 – 1.14 0.539 101 1010 all phecode
348 Other conditions of brain Neurological 1.01 0.958 – 1.06 0.788 1793 17894 all phecode
348.2 Cerebral edema and compression of brain Neurological 1.01 0.941 – 1.08 0.826 905 9034 all phecode
348.4 Cerebral cysts Neurological 1.05 0.919 – 1.21 0.457 229 2290 all phecode
348.7 Coma Neurological 0.964 0.841 – 1.11 0.603 229 2275 all phecode
348.8 Encephalopathy, not elsewhere classified Neurological 1.05 0.981 – 1.13 0.15 853 8479 all phecode
348.9 Other conditions of brain, NOS Neurological 0.992 0.95 – 1.04 0.716 2341 23287 all phecode
349
Other and unspecified disorders of the nervous
Other and unspecified disorders of the nervous system
 Neurological 1.01 0.944 – 1.08 0.76 941 9385 all phecode
350 Abnormal movement Neurological 1.01 0.986 – 1.04 0.362 6706 38762 all phecode
350.1 Abnormal involuntary movements Neurological 1.01 0.973 – 1.05 0.618 3273 30524 all phecode
350.2 Abnormality of gait Neurological 1.01 0.974 – 1.04 0.664 3920 30520 all phecode
350.3 Lack of coordination Neurological 1 0.941 – 1.07 0.939 1062 10554 all phecode
350.5 Abnormal reflex Neurological 1 0.863 – 1.16 0.999 200 1988 all phecode
350.6 Disturbances of sensation of smell and taste Neurological 0.983 0.899 – 1.07 0.704 558 5576 all phecode
351 Other peripheral nerve disorders Neurological 1.06 1.04 – 1.09 4.15e-06 7401 34460 all phecode
352 Disorders of other cranial nerves Neurological 1.01 0.961 – 1.06 0.664 1714 17106 all phecode
352.1 Trigeminal nerve disorders [CN5] Neurological 1.02 0.935 – 1.12 0.618 535 5344 all phecode
352.2 Facial nerve disorders [CN7] Neurological 1.02 0.945 – 1.1 0.644 783 7826 all phecode
353 Nerve root and plexus disorders Neurological 1.06 1.02 – 1.09 0.00119 4256 33369 all phecode
353.1 Nerve plexus lesions Neurological 0.987 0.889 – 1.1 0.804 390 3900 all phecode
353.2 Nerve root lesions Neurological 1.01 0.842 – 1.21 0.908 130 1287 all phecode
355 Complex regional/central pain syndrome Neurological 1.13 1.03 – 1.23 0.01 531 5295 all phecode
355.1 Chronic pain syndrome Neurological 1.21 1.13 – 1.3 1.91e-07 843 8386 all phecode
356 Hereditary and idiopathic peripheral neuropathy Neurological 1.09 1.05 – 1.14 5.49e-05 2335 20731 all phecode
357 Inflammatory and toxic neuropathy Neurological 1.08 1.04 – 1.12 3.23e-05 3472 29956 all phecode
358 Myoneural disorders Neurological 1.04 0.983 – 1.11 0.159 1147 11391 all phecode
358.1 Myasthenia gravis Neurological 1.09 0.894 – 1.32 0.401 109 1082 all phecode
359 Muscular dystrophies and other myopathies Neurological 0.98 0.921 – 1.04 0.533 1134 11274 all phecode
359.1 Muscular dystrophies Neurological 0.983 0.761 – 1.27 0.894 64 632 all phecode
359.2 Myopathy Neurological 0.977 0.917 – 1.04 0.48 1092 10843 all phecode
360 Disorders of the globe Sense Organs 0.947 0.791 – 1.13 0.556 131 1276 all phecode
360.2 Progressive myopia Sense Organs 0.98 0.761 – 1.26 0.878 65 640 all phecode
361 Retinal detachments and defects Sense Organs 1 0.928 – 1.08 0.965 733 7131 all phecode
361.1 Retinal detachment with retinal defect Sense Organs 1.03 0.918 – 1.16 0.584 302 2962 all phecode
362 Other retinal disorders Sense Organs 1.01 0.978 – 1.05 0.455 3569 22997 all phecode
362.2
Degeneration of macula and posterior pole of
Degeneration of macula and posterior pole of retina
 Sense Organs 1.02 0.976 – 1.07 0.359 2172 15483 all phecode
362.21 Macular degeneration, dry Sense Organs 0.943 0.852 – 1.04 0.252 419 3438 all phecode
362.22 Macular degeneration, wet Sense Organs 1.16 0.983 – 1.36 0.0802 148 1184 all phecode
362.23 Cystoid macular degeneration of retina Sense Organs 1.11 1 – 1.23 0.0486 408 3839 all phecode
362.26 Macular puckering of retina Sense Organs 1.02 0.952 – 1.09 0.59 976 8610 all phecode
362.27 Drusen (degenerative) of retina Sense Organs 0.915 0.832 – 1.01 0.0664 488 4558 all phecode
362.29 Macular degeneration (senile) of retina NOS Sense Organs 1.03 0.983 – 1.09 0.197 1883 13955 all phecode
362.3 Other nondiabetic retinopathy Sense Organs 1.02 0.954 – 1.09 0.565 976 8527 all phecode
362.31 Separation of retinal layers Sense Organs 0.981 0.885 – 1.09 0.716 413 4056 all phecode
362.4 Retinal vascular changes and abnomalities Sense Organs 1.05 0.971 – 1.14 0.21 662 5933 all phecode
362.6 Peripheral retinal degenerations Sense Organs 0.985 0.886 – 1.09 0.777 392 3787 all phecode
362.7 Hereditary retinal dystrophies Sense Organs 1.08 0.944 – 1.24 0.258 215 2103 all phecode
362.8 Retinal hemorrhage/ischemia Sense Organs 0.944 0.825 – 1.08 0.408 241 2368 all phecode
362.9 Retinal edema Sense Organs 1.04 0.924 – 1.17 0.528 324 2936 all phecode
363
Chorioretinal inflammations, scars, and other
Chorioretinal inflammations, scars, and other disorders of choroid
 Sense Organs 0.965 0.877 – 1.06 0.462 492 4746 all phecode
363.3 Chorioretinal scars Sense Organs 1.01 0.9 – 1.13 0.88 332 3184 all phecode
364 Corneal opacity and other disorders of cornea Sense Organs 0.984 0.924 – 1.05 0.605 1132 10772 all phecode
364.1 Corneal opacity Sense Organs 0.861 0.775 – 0.958 0.00579 394 3846 all phecode
364.2 Corneal edema Sense Organs 0.938 0.778 – 1.13 0.506 123 1208 all phecode
364.4 Corneal degenerations Sense Organs 1.03 0.925 – 1.14 0.608 402 3962 all phecode
364.41 Keratoconus Sense Organs 1.06 0.824 – 1.35 0.668 75 739 all phecode
364.5 Corneal dystrophy Sense Organs 0.958 0.873 – 1.05 0.374 502 4682 all phecode
364.51 Fuchs' dystrophy Sense Organs 0.956 0.843 – 1.08 0.482 266 2521 all phecode
364.9 Cornea replaced by transplant Sense Organs 0.939 0.751 – 1.17 0.584 91 885 all phecode
365 Glaucoma Sense Organs 0.98 0.941 – 1.02 0.338 2672 21326 all phecode
365.1 Open-angle glaucoma Sense Organs 0.974 0.901 – 1.05 0.518 705 6491 all phecode
365.11 Primary open angle glaucoma Sense Organs 1.04 0.934 – 1.15 0.511 403 3681 all phecode
365.2 Primary angle-closure glaucoma Sense Organs 1.02 0.897 – 1.17 0.733 251 2370 all phecode
366 Cataract Sense Organs 0.997 0.971 – 1.02 0.817 8611 28043 all phecode
366.1 Nonsenile Cataract Sense Organs 1.02 0.885 – 1.18 0.753 207 1979 all phecode
366.2 Senile cataract Sense Organs 0.97 0.94 – 1 0.0515 5480 24980 all phecode
367
Disorders of refraction and accommodation
Disorders of refraction and accommodation; blindness and low vision
 Sense Organs 0.978 0.955 – 1 0.0715 8967 37779 all phecode
367.1 Myopia Sense Organs 0.964 0.935 – 0.994 0.0177 5014 34677 all phecode
367.2 Astigmatism Sense Organs 0.957 0.925 – 0.989 0.00846 4161 32463 all phecode
367.8 Hypermetropia Sense Organs 0.989 0.944 – 1.04 0.635 2039 18599 all phecode
367.9 Blindness and low vision Sense Organs 1.04 0.977 – 1.1 0.242 1277 12356 all phecode
368 Visual disturbances Sense Organs 1.01 0.985 – 1.04 0.354 5715 39599 all phecode
368.1 Amblyopia Sense Organs 1.03 0.951 – 1.12 0.443 651 6479 all phecode
368.2 Diplopia and disorders of binocular vision Sense Organs 1.03 0.965 – 1.1 0.387 1087 10786 all phecode
368.3 Anisometropia Sense Organs 0.972 0.847 – 1.12 0.686 219 2168 all phecode
368.4 Visual field defects Sense Organs 1.01 0.951 – 1.08 0.706 1132 11173 all phecode
368.9 Subjective visual disturbances Sense Organs 1.02 0.953 – 1.08 0.629 1070 10620 all phecode
368.91 Psychophysical visual disturbances Sense Organs 1.07 0.888 – 1.3 0.469 120 1171 all phecode
369 Infection of the eye Sense Organs 0.951 0.916 – 0.987 0.00853 3185 28240 all phecode
369.2 Eye infection, viral Sense Organs 0.927 0.845 – 1.02 0.109 502 4954 all phecode
369.5 Conjunctivitis, infectious Sense Organs 0.953 0.916 – 0.992 0.0199 2716 24970 all phecode
370 Keratitis Sense Organs 0.999 0.944 – 1.06 0.976 1365 13169 all phecode
370.1 Corneal ulcer Sense Organs 1.02 0.887 – 1.17 0.786 223 2194 all phecode
370.2 Superficial keratitis Sense Organs 1.03 0.938 – 1.12 0.581 546 5393 all phecode
370.3 Keratoconjunctivitis Sense Organs 1.02 0.941 – 1.11 0.602 649 6263 all phecode
370.31 Keratoconjunctivitis sicca Sense Organs 0.868 0.743 – 1.01 0.0749 179 1677 all phecode
371 Inflammation of the eye Sense Organs 0.981 0.95 – 1.01 0.243 4414 32310 all phecode
371.1 Uveitis, noninfectious or NOS Sense Organs 0.99 0.906 – 1.08 0.831 541 5278 all phecode
371.2 Conjunctivitis, noninfectious Sense Organs 0.951 0.887 – 1.02 0.157 906 8939 all phecode
371.21 Allergic conjunctivitis Sense Organs 0.921 0.853 – 0.993 0.033 756 7515 all phecode
371.3 Inflammation of eyelids Sense Organs 0.978 0.943 – 1.01 0.238 3398 26983 all phecode
371.33 Noninfectious dermatoses of eyelid Sense Organs 1.03 0.861 – 1.24 0.735 133 1291 all phecode
372 Disorders of conjunctiva Sense Organs 0.973 0.914 – 1.04 0.396 1118 10728 all phecode
374 Other disorders of eyelids Sense Organs 0.987 0.95 – 1.03 0.521 2940 24188 all phecode
374.1 Ectropion or entropion Sense Organs 0.96 0.868 – 1.06 0.432 431 4084 all phecode
374.2 Lagophthalmos Sense Organs 1.11 0.968 – 1.27 0.136 235 2335 all phecode
374.3 Ptosis of eyelid Sense Organs 0.971 0.912 – 1.03 0.363 1102 10734 all phecode
374.6 Dermatochalasis Sense Organs 0.994 0.931 – 1.06 0.849 1040 9720 all phecode
375 Disorders of lacrimal system Sense Organs 1.01 0.974 – 1.05 0.624 3694 26045 all phecode
375.1 Dry eyes Sense Organs 1 0.969 – 1.04 0.868 4040 26751 all phecode
375.2 Epiphora Sense Organs 0.938 0.851 – 1.03 0.201 442 4354 all phecode
376 Disorders of the orbit Sense Organs 0.939 0.841 – 1.05 0.267 352 3508 all phecode
377 Disorders of optic nerve and visual pathways Sense Organs 1.07 0.995 – 1.14 0.0705 913 9021 all phecode
377.1 Optic atrophy Sense Organs 0.99 0.874 – 1.12 0.879 283 2793 all phecode
377.3 Optic neuritis/neuropathy Sense Organs 1.12 1.03 – 1.22 0.00862 585 5775 all phecode
378
Strabismus and other disorders of binocular eye
Strabismus and other disorders of binocular eye movements
 Sense Organs 0.959 0.905 – 1.02 0.163 1275 12460 all phecode
378.1 Strabismus (not specified as paralytic) Sense Organs 0.971 0.903 – 1.04 0.433 828 8130 all phecode
378.2 Nystagmus and other irregular eye movements Sense Organs 0.915 0.784 – 1.07 0.265 170 1686 all phecode
378.5 Paralytic strabismus Sense Organs 0.992 0.887 – 1.11 0.884 349 3437 all phecode
379 Other disorders of eye Sense Organs 0.983 0.953 – 1.01 0.289 5046 29999 all phecode
379.1 Scleritis and episcleritis Sense Organs 1.04 0.891 – 1.22 0.607 176 1743 all phecode
379.2 Disorders of vitreous body Sense Organs 0.979 0.945 – 1.02 0.262 3634 23186 all phecode
379.3 Aphakia and other disorders of lens Sense Organs 1.05 0.877 – 1.26 0.577 135 1258 all phecode
379.4 Anomalies of pupillary function Sense Organs 0.97 0.856 – 1.1 0.635 287 2833 all phecode
379.5 Disorders of iris and ciliary body Sense Organs 1.06 0.935 – 1.2 0.373 304 2948 all phecode
379.51 Pigmentary iris degeneration Sense Organs 0.769 0.597 – 0.99 0.0414 77 731 all phecode
379.9 Pain, swelling or discharge of eye Sense Organs 1.02 0.957 – 1.08 0.577 1129 11130 all phecode
380 Disorders of external ear Sense Organs 0.96 0.919 – 1 0.0707 2242 20393 all phecode
380.1 Otitis externa Sense Organs 1.04 0.98 – 1.09 0.216 1469 14580 all phecode
380.4 Impacted cerumen Sense Organs 0.975 0.937 – 1.02 0.227 2648 23557 all phecode
381 Otitis media and Eustachian tube disorders Sense Organs 1.03 0.999 – 1.07 0.0583 4255 36417 all phecode
381.1 Otitis media Sense Organs 1.06 1.02 – 1.1 0.00466 3079 29813 all phecode
381.11 Suppurative and unspecified otitis media Sense Organs 1.05 1.01 – 1.09 0.0207 2610 25602 all phecode
381.2 Eustachian tube disorders Sense Organs 0.995 0.947 – 1.05 0.843 1816 17827 all phecode
381.3 Mastoiditis & related conditions Sense Organs 1.02 0.867 – 1.21 0.786 153 1530 all phecode
381.9 Otorrhea Sense Organs 1.07 0.959 – 1.19 0.228 372 3713 all phecode
382 Otalgia Sense Organs 1.07 1.02 – 1.12 0.0049 1884 18673 all phecode
383 Otosclerosis Sense Organs 0.928 0.771 – 1.12 0.432 124 1240 all phecode
384 Other disorders of tympanic membrane Sense Organs 1.07 0.974 – 1.17 0.165 516 5156 all phecode
384.1 Myringitis Sense Organs 1.18 0.882 – 1.57 0.267 51 502 all phecode
384.4 Perforation of tympanic membrane Sense Organs 1.08 0.975 – 1.2 0.139 403 4029 all phecode
385 Other disorders of middle ear and mastoid Sense Organs 0.977 0.884 – 1.08 0.649 432 4320 all phecode
385.3 Cholesteatoma Sense Organs 0.957 0.846 – 1.08 0.477 277 2770 all phecode
385.5
Tympanosclerosis and middle ear disease related
Tympanosclerosis and middle ear disease related to otitis media
 Sense Organs 0.838 0.694 – 1.01 0.0672 118 1180 all phecode
386
Vertiginous syndromes and other disorders of
Vertiginous syndromes and other disorders of vestibular system
 Sense Organs 1.04 0.991 – 1.09 0.11 1882 18186 all phecode
386.1 Meniere's disease Sense Organs 1 0.894 – 1.13 0.955 319 3156 all phecode
386.2 Peripheral or central vertigo Sense Organs 1.05 0.995 – 1.1 0.0765 1586 15423 all phecode
386.21 Central origin vertigo Sense Organs 1.05 0.991 – 1.12 0.0954 1208 11844 all phecode
386.3 Labyrinthitis Sense Organs 1.04 0.988 – 1.1 0.132 1482 14530 all phecode
386.9
Dizziness and giddiness (Light-headedness and
Dizziness and giddiness (Light-headedness and vertigo)
 Sense Organs 1.01 0.985 – 1.04 0.411 6933 38286 all phecode
388 Other disorders of ear Sense Organs 1.03 0.963 – 1.1 0.387 960 9501 all phecode
389 Hearing loss Sense Organs 1.01 0.988 – 1.04 0.313 8182 38069 all phecode
389.1 Sensorineural hearing loss Sense Organs 0.987 0.954 – 1.02 0.44 4107 29258 all phecode
389.2 Conductive hearing loss Sense Organs 1.02 0.948 – 1.09 0.649 905 9042 all phecode
389.3 Degenerative and vascular disorders of ear Sense Organs 0.96 0.829 – 1.11 0.59 192 1808 all phecode
389.4 Tinnitus Sense Organs 0.987 0.945 – 1.03 0.564 2291 22130 all phecode
389.5 Disorders of acoustic nerve Sense Organs 0.997 0.831 – 1.2 0.975 124 1229 all phecode
394 Rheumatic disease of the heart valves Circulatory System 1.02 0.963 – 1.07 0.552 1458 13732 all phecode
394.1 Mitral valve stenosis and aortic valve stenosis Circulatory System 0.907 0.811 – 1.01 0.0884 350 3415 all phecode
394.2 Mitral valve disease Circulatory System 1.03 0.933 – 1.14 0.562 462 4560 all phecode
394.3 Aortic valve disease Circulatory System 0.961 0.821 – 1.13 0.621 176 1691 all phecode
394.4 Acute rheumatic heart disease Circulatory System 1.18 0.902 – 1.55 0.227 55 546 all phecode
394.7 Disease of tricuspid valve Circulatory System 1.03 0.944 – 1.12 0.505 587 5739 all phecode
395 Heart valve disorders Circulatory System 1.02 0.984 – 1.05 0.311 3976 28748 all phecode
395.1 Nonrheumatic mitral valve disorders Circulatory System 1.03 0.984 – 1.08 0.204 2175 20441 all phecode
395.2 Nonrheumatic aortic valve disorders Circulatory System 0.981 0.936 – 1.03 0.408 2060 17194 all phecode
395.3 Nonrheumatic tricuspid valve disorders Circulatory System 1.02 0.931 – 1.12 0.649 493 4864 all phecode
395.4 Nonrheumatic pulmonary valve disorders Circulatory System 0.905 0.74 – 1.11 0.331 108 1080 all phecode
395.6 Heart valve replaced Circulatory System 0.995 0.936 – 1.06 0.868 1177 10833 all phecode
396 Abnormal heart sounds Circulatory System 1.02 0.991 – 1.05 0.167 4718 34395 all phecode
401 Hypertension Circulatory System 1.08 1.06 – 1.11 5.15e-14 23317 23367 all phecode
401.1 Essential hypertension Circulatory System 1.08 1.06 – 1.11 4.55e-14 23158 23364 all phecode
401.2 Hypertensive heart and/or renal disease Circulatory System 1.08 1.04 – 1.13 0.000129 3503 14616 all phecode
401.21 Hypertensive heart disease Circulatory System 1.04 0.966 – 1.12 0.307 893 6607 all phecode
401.22 Hypertensive chronic kidney disease Circulatory System 1.1 1.05 – 1.15 2.36e-05 2584 13072 all phecode
401.3 Other hypertensive complications Circulatory System 1.08 1.04 – 1.13 0.000278 2679 15833 all phecode
411 Ischemic Heart Disease Circulatory System 1.08 1.05 – 1.11 1.88e-09 8807 30299 all phecode
411.1 Unstable angina (intermediate coronary syndrome) Circulatory System 1.08 1.01 – 1.16 0.0302 937 8574 all phecode
411.2 Myocardial infarction Circulatory System 1.11 1.07 – 1.15 2.43e-08 3594 21716 all phecode
411.3 Angina pectoris Circulatory System 1.08 1.03 – 1.12 0.000644 2485 18304 all phecode
411.4 Coronary atherosclerosis Circulatory System 1.08 1.05 – 1.11 3.54e-08 7555 27492 all phecode
411.41 Aneurysm and dissection of heart Circulatory System 1.08 0.909 – 1.27 0.392 156 1529 all phecode
411.8
Other chronic ischemic heart disease
Other chronic ischemic heart disease, unspecified
 Circulatory System 1.08 1.05 – 1.11 1.27e-07 6331 25741 all phecode
411.9
Other acute and subacute forms of ischemic
Other acute and subacute forms of ischemic heart disease
 Circulatory System 1.07 0.967 – 1.18 0.191 442 4211 all phecode
414 Other forms of chronic heart disease Circulatory System 1.04 1 – 1.08 0.0465 3101 22616 all phecode
414.2 ASCVD Circulatory System 1.09 1.01 – 1.18 0.0366 718 6816 all phecode
415 Pulmonary heart disease Circulatory System 1.05 1.01 – 1.08 0.0167 3366 30208 all phecode
415.1 Acute pulmonary heart disease Circulatory System 1.05 1.01 – 1.11 0.0284 1912 19014 all phecode
415.11 Pulmonary embolism and infarction, acute Circulatory System 1.05 1.01 – 1.11 0.028 1906 18953 all phecode
415.2 Chronic pulmonary heart disease Circulatory System 1.06 1 – 1.11 0.0319 1808 17605 all phecode
415.21 Primary pulmonary hypertension Circulatory System 1.02 0.942 – 1.1 0.631 706 7032 all phecode
416 Cardiomegaly Circulatory System 0.997 0.94 – 1.06 0.928 1254 12372 all phecode
418 Nonspecific chest pain Circulatory System 1.05 1.02 – 1.07 3.64e-05 12650 33952 all phecode
418.1 Precordial pain Circulatory System 1.11 1.05 – 1.17 0.000263 1471 13782 all phecode
420 Carditis Circulatory System 1.01 0.954 – 1.06 0.847 1588 15680 all phecode
420.1 Myocarditis Circulatory System 0.833 0.673 – 1.03 0.0936 97 958 all phecode
420.2 Pericarditis Circulatory System 0.996 0.927 – 1.07 0.923 842 8402 all phecode
420.21 Acute pericarditis Circulatory System 1.03 0.882 – 1.21 0.697 177 1764 all phecode
420.22 Chronic pericarditis Circulatory System 0.961 0.789 – 1.17 0.689 117 1153 all phecode
420.3 Endocarditis Circulatory System 1.03 0.959 – 1.11 0.387 764 7535 all phecode
425 Cardiomyopathy Circulatory System 1.01 0.963 – 1.05 0.738 2078 19881 all phecode
425.1 Primary/intrinsic cardiomyopathies Circulatory System 1.01 0.968 – 1.06 0.552 1989 19025 all phecode
425.11 Hypertrophic obstructive cardiomyopathy Circulatory System 0.942 0.818 – 1.09 0.411 208 2050 all phecode
425.12 Other hypertrophic cardiomyopathy Circulatory System 0.983 0.85 – 1.14 0.813 201 1992 all phecode
425.2 Secondary/extrinsic cardiomyopathies Circulatory System 0.976 0.87 – 1.09 0.677 317 3170 all phecode
425.8 Other cardiomyopathy Circulatory System 0.831 0.673 – 1.03 0.0843 95 931 all phecode
426 Cardiac conduction disorders Circulatory System 1.02 1 – 1.05 0.0442 12327 25440 all phecode
426.2 Atrioventricular [AV] block Circulatory System 0.981 0.933 – 1.03 0.451 1903 11501 all phecode
426.21 First degree AV block Circulatory System 0.981 0.925 – 1.04 0.532 1313 8899 all phecode
426.22 Mobitz II AV block Circulatory System 1.13 0.86 – 1.48 0.386 64 553 all phecode
426.23 Second degree AV block Circulatory System 0.986 0.855 – 1.14 0.845 216 1925 all phecode
426.24 Atrioventricular block, complete Circulatory System 1.04 0.939 – 1.14 0.484 461 3823 all phecode
426.25 Other heart block Circulatory System 0.933 0.805 – 1.08 0.36 203 1803 all phecode
426.3 Bundle branch block Circulatory System 1.03 0.983 – 1.08 0.222 2306 13999 all phecode
426.31 Right bundle branch block Circulatory System 1.02 0.967 – 1.08 0.433 1423 10758 all phecode
426.32 Left bundle branch block Circulatory System 1.05 0.978 – 1.12 0.192 969 8110 all phecode
426.4 Anomalous atrioventricular excitation Circulatory System 0.881 0.698 – 1.11 0.285 82 820 all phecode
426.7 Abnormal electrocardiogram [ECG] [EKG] Circulatory System 1.03 1 – 1.05 0.0449 10577 25186 all phecode
426.8 Other cardiac conduction disorders Circulatory System 0.991 0.914 – 1.07 0.822 679 6650 all phecode
426.9 Cardiac pacemaker/device in situ Circulatory System 1 0.954 – 1.06 0.86 1754 11536 all phecode
426.91 Cardiac pacemaker in situ Circulatory System 1.01 0.951 – 1.08 0.705 1171 8184 all phecode
426.92 Cardiac defibrillator in situ Circulatory System 0.993 0.924 – 1.07 0.857 846 7320 all phecode
427 Cardiac dysrhythmias Circulatory System 1.01 0.993 – 1.03 0.185 17397 25735 all phecode
427.1 Paroxysmal tachycardia, unspecified Circulatory System 1.02 0.977 – 1.06 0.363 2474 18178 all phecode
427.11 Paroxysmal supraventricular tachycardia Circulatory System 1.03 0.98 – 1.09 0.223 1595 14293 all phecode
427.12 Paroxysmal ventricular tachycardia Circulatory System 0.995 0.936 – 1.06 0.876 1181 9915 all phecode
427.2 Atrial fibrillation and flutter Circulatory System 1.01 0.979 – 1.05 0.488 5313 18688 all phecode
427.21 Atrial fibrillation Circulatory System 1.01 0.975 – 1.04 0.649 5188 18409 all phecode
427.22 Atrial flutter Circulatory System 0.997 0.946 – 1.05 0.913 1693 11042 all phecode
427.3 Other specified cardiac dysrhythmias Circulatory System 1.01 0.989 – 1.04 0.256 8688 25552 all phecode
427.4 Cardiac arrest and ventricular fibrillation Circulatory System 1.02 0.931 – 1.11 0.685 536 5233 all phecode
427.41 Ventricular fibrillation and flutter Circulatory System 0.845 0.732 – 0.975 0.0207 216 2118 all phecode
427.42 Cardiac arrest Circulatory System 1.09 0.988 – 1.21 0.0851 410 4034 all phecode
427.5 Arrhythmia (cardiac) NOS Circulatory System 0.997 0.969 – 1.03 0.829 6905 25457 all phecode
427.6 Premature beats Circulatory System 0.993 0.95 – 1.04 0.748 2359 16248 all phecode
427.61 Supraventricular premature beats Circulatory System 1.02 0.94 – 1.1 0.646 670 6287 all phecode
427.7 Tachycardia NOS Circulatory System 1.02 0.992 – 1.06 0.142 5124 25531 all phecode
427.8 Sinoatrial node dysfunction (Bradycardia) Circulatory System 1.03 0.957 – 1.1 0.468 912 7501 all phecode
427.9 Palpitations Circulatory System 0.979 0.948 – 1.01 0.213 4430 24505 all phecode
428 Congestive heart failure; nonhypertensive Circulatory System 1.04 1 – 1.07 0.0285 4300 23663 all phecode
428.1 Congestive heart failure (CHF) NOS Circulatory System 1.03 0.996 – 1.07 0.0805 3756 22446 all phecode
428.2 Heart failure NOS Circulatory System 1.04 1 – 1.08 0.0271 3701 21722 all phecode
428.3
Heart failure with reduced EF [Systolic or
Heart failure with reduced EF [Systolic or combined heart failure]
 Circulatory System 1.04 0.99 – 1.09 0.113 1765 14476 all phecode
428.4
Heart failure with preserved EF [Diastolic
Heart failure with preserved EF [Diastolic heart failure]
 Circulatory System 1.07 1.01 – 1.13 0.0119 1648 13395 all phecode
429
Ill-defined descriptions and complications of
Ill-defined descriptions and complications of heart disease
 Circulatory System 1.02 0.997 – 1.04 0.0933 12635 32504 all phecode
429.1 Heart transplant/surgery Circulatory System 1.01 0.948 – 1.07 0.833 1219 11696 all phecode
429.2 Abnormal function study of cardiovascular system Circulatory System 1.03 1 – 1.06 0.0263 6322 29232 all phecode
429.3 Symptoms involving cardiovascular system Circulatory System 1.02 0.994 – 1.04 0.141 9650 32421 all phecode
429.9 Cardiac complications, not elsewhere classified Circulatory System 1.02 0.941 – 1.1 0.667 723 7072 all phecode
430 Intracranial hemorrhage Circulatory System 1 0.93 – 1.08 0.972 789 7842 all phecode
430.1 Subarachnoid hemorrhage Circulatory System 0.939 0.826 – 1.07 0.34 261 2610 all phecode
430.2 Intracerebral hemorrhage Circulatory System 1.08 0.969 – 1.2 0.163 368 3671 all phecode
430.3 Subdural hemorrhage Circulatory System 1.01 0.891 – 1.14 0.879 272 2680 all phecode
433 Cerebrovascular disease Circulatory System 1.04 1.01 – 1.08 0.00349 5463 32242 all phecode
433.1 Occlusion and stenosis of precerebral arteries Circulatory System 1.06 1.01 – 1.11 0.0205 1978 16212 all phecode
433.11
Occlusion of cerebral arteries, with cerebral
Occlusion of cerebral arteries, with cerebral infarction
 Circulatory System 0.972 0.853 – 1.11 0.671 260 2517 all phecode
433.12 Cerebral atherosclerosis Circulatory System 1.32 1.05 – 1.66 0.0171 80 789 all phecode
433.2 Occlusion of cerebral arteries Circulatory System 1.02 0.976 – 1.06 0.402 2437 21732 all phecode
433.21
Cerebral artery occlusion, with cerebral
Cerebral artery occlusion, with cerebral infarction
 Circulatory System 1.02 0.979 – 1.07 0.312 2357 21103 all phecode
433.3 Cerebral ischemia Circulatory System 1.01 0.968 – 1.05 0.726 2780 22868 all phecode
433.31 Transient cerebral ischemia Circulatory System 1.01 0.969 – 1.06 0.609 2409 20762 all phecode
433.5 Cerebral aneurysm Circulatory System 1.12 1.02 – 1.23 0.0204 474 4724 all phecode
433.6 Acute, but ill-defined cerebrovascular disease Circulatory System 0.948 0.86 – 1.05 0.287 464 4518 all phecode
433.8 Late effects of cerebrovascular disease Circulatory System 0.96 0.886 – 1.04 0.319 695 6822 all phecode
440 Atherosclerosis Circulatory System 1.07 1.03 – 1.12 0.0013 2477 19724 all phecode
440.1 Atherosclerosis of renal artery Circulatory System 1.14 0.997 – 1.31 0.0549 231 2291 all phecode
440.2 Atherosclerosis of the extremities Circulatory System 1.1 1.04 – 1.16 0.000782 1516 13532 all phecode
440.21
Atherosclerosis of native arteries of the
Atherosclerosis of native arteries of the extremities with ulceration or gangrene
 Circulatory System 1.09 0.965 – 1.24 0.161 274 2669 all phecode
440.22
Atherosclerosis of native arteries of the
Atherosclerosis of native arteries of the extremities with intermittent claudication
 Circulatory System 1.09 1.02 – 1.16 0.00849 1040 9647 all phecode
440.9 Atherosclerosis of aorta Circulatory System 1.02 0.947 – 1.09 0.641 846 8124 all phecode
441 Vascular insufficiency of intestine Circulatory System 1.15 1.05 – 1.26 0.00257 515 5115 all phecode
441.1 Acute vascular insufficiency of intestine Circulatory System 1.07 0.937 – 1.22 0.318 240 2387 all phecode
441.2 Chronic vascular insufficiency of intestine Circulatory System 1.24 1.05 – 1.46 0.0101 154 1536 all phecode
442 Other aneurysm Circulatory System 1.03 0.994 – 1.08 0.0998 2779 21466 all phecode
442.1 Aortic aneurysm Circulatory System 1.03 0.984 – 1.08 0.201 2054 16492 all phecode
442.11 Abdominal aortic aneurysm Circulatory System 1.07 1 – 1.13 0.0355 1189 10558 all phecode
442.2 Aneurysm of iliac artery Circulatory System 1.19 1.03 – 1.37 0.0175 202 2002 all phecode
442.3 Aneurysm of artery of lower extremity Circulatory System 1.03 0.88 – 1.2 0.73 179 1765 all phecode
442.4 Arterial dissection Circulatory System 1.08 0.928 – 1.26 0.318 184 1840 all phecode
442.8 Aneurysm of other specified artery Circulatory System 1.02 0.915 – 1.13 0.77 399 3978 all phecode
443 Peripheral vascular disease Circulatory System 1.06 1.02 – 1.1 0.00485 3086 24814 all phecode
443.1 Raynaud's syndrome Circulatory System 1 0.931 – 1.08 0.925 742 7390 all phecode
443.7
Peripheral angiopathy in diseases classified
Peripheral angiopathy in diseases classified elsewhere
 Circulatory System 1.04 0.907 – 1.2 0.556 220 2087 all phecode
443.8 Other specified peripheral vascular diseases Circulatory System 1.06 1.02 – 1.11 0.00515 2557 21985 all phecode
443.9 Peripheral vascular disease, unspecified Circulatory System 1.07 1.02 – 1.11 0.00417 2341 18862 all phecode
444 Arterial embolism and thrombosis Circulatory System 1.08 1 – 1.16 0.0414 848 8423 all phecode
444.1
Arterial embolism and thrombosis of lower
Arterial embolism and thrombosis of lower extremity artery
 Circulatory System 1.1 0.977 – 1.24 0.116 313 3099 all phecode
444.2 Embolism and thrombosis of abdominal aorta Circulatory System 1.04 0.882 – 1.23 0.633 155 1548 all phecode
446 Polyarteritis nodosa and allied conditions Circulatory System 1.04 0.939 – 1.14 0.487 460 4559 all phecode
446.4 Wegener's granulomatosis Circulatory System 0.93 0.765 – 1.13 0.468 109 1075 all phecode
446.5 Giant cell arteritis Circulatory System 1.14 0.902 – 1.43 0.28 79 749 all phecode
446.9 Arteritis NOS Circulatory System 1.08 0.956 – 1.23 0.21 289 2876 all phecode
447 Other disorders of arteries and arterioles Circulatory System 1.06 1.01 – 1.1 0.00958 2647 22765 all phecode
447.1 Stricture of artery Circulatory System 1.12 1.02 – 1.23 0.0145 523 5163 all phecode
447.7 Aortic ectasia Circulatory System 1.02 0.951 – 1.1 0.545 804 7938 all phecode
448 Disease of capillaries Circulatory System 0.919 0.866 – 0.975 0.00497 1237 12127 all phecode
450 Noninfectious disorders of lymphatic channels Circulatory System 0.99 0.946 – 1.04 0.664 2104 20985 all phecode
451 Phlebitis and thrombophlebitis Circulatory System 0.984 0.911 – 1.06 0.683 738 7355 all phecode
451.2
Phlebitis and thrombophlebitis of lower
Phlebitis and thrombophlebitis of lower extremities
 Circulatory System 0.92 0.804 – 1.05 0.224 244 2437 all phecode
452 Other venous embolism and thrombosis Circulatory System 1.03 0.999 – 1.06 0.0613 4957 29867 all phecode
452.1 Iatrogenic pulmonary embolism and infarction Circulatory System 1.03 0.908 – 1.17 0.636 276 2747 all phecode
452.2 Deep vein thrombosis [DVT] Circulatory System 1.04 1 – 1.08 0.0472 3260 26940 all phecode
452.8 Postphlebitic syndrome Circulatory System 1.1 0.935 – 1.3 0.243 154 1529 all phecode
453 Chronic venous hypertension Circulatory System 0.989 0.857 – 1.14 0.879 220 2168 all phecode
454 Varicose veins Circulatory System 0.969 0.931 – 1.01 0.122 2827 24555 all phecode
454.1 Varicose veins of lower extremity Circulatory System 0.97 0.93 – 1.01 0.169 2469 21426 all phecode
454.11 Varicose veins of lower extremity, symptomtic Circulatory System 0.981 0.93 – 1.03 0.485 1565 15056 all phecode
455 Hemorrhoids Circulatory System 0.999 0.97 – 1.03 0.94 5799 29818 all phecode
456 Chronic venous insufficiency [CVI] Circulatory System 0.984 0.947 – 1.02 0.396 3097 24898 all phecode
457
Encounter for long-term (current) use of
Encounter for long-term (current) use of anticoagulants, antithrombotics, aspirin
 Circulatory System 1.05 0.999 – 1.1 0.0548 2095 15309 all phecode
457.2
Encounter for long-term (current) use of
Encounter for long-term (current) use of antiplatelets/antithrombotics
 Circulatory System 1.06 0.942 – 1.19 0.34 324 3221 all phecode
457.3 Encounter for long-term (current) use of aspirin Circulatory System 1.05 0.997 – 1.1 0.0664 1973 14689 all phecode
458 Hypotension Circulatory System 1.03 0.996 – 1.06 0.0926 5091 32185 all phecode
458.1 Orthostatic hypotension Circulatory System 1.03 0.969 – 1.09 0.382 1344 12938 all phecode
458.2 Iatrogenic hypotension Circulatory System 1.07 1 – 1.13 0.0465 1109 11012 all phecode
458.9 Hypotension NOS Circulatory System 1.03 0.998 – 1.06 0.0709 4618 31186 all phecode
459 Other disorders of circulatory system Circulatory System 1.03 1.01 – 1.06 0.0179 7825 34792 all phecode
459.1 Hemorrhage NOS Circulatory System 0.962 0.895 – 1.03 0.295 834 8215 all phecode
459.7 Blood vessel replaced Circulatory System 1.05 0.988 – 1.11 0.122 1305 13023 all phecode
459.9 Circulatory disease NEC Circulatory System 1.04 1.01 – 1.07 0.00827 6706 33592 all phecode
464 Acute sinusitis Respiratory 0.987 0.957 – 1.02 0.414 4792 32137 all phecode
465
Acute upper respiratory infections of multiple
Acute upper respiratory infections of multiple or unspecified sites
 Respiratory 0.979 0.956 – 1 0.0702 9601 35915 all phecode
465.2 Acute pharyngitis Respiratory 1 0.974 – 1.03 0.842 5310 32365 all phecode
465.4 Acute laryngitis and tracheitis Respiratory 0.941 0.852 – 1.04 0.228 443 4428 all phecode
470 Septal Deviations/Turbinate Hypertrophy Respiratory 1.01 0.959 – 1.06 0.756 1797 17640 all phecode
471 Nasal polyps Respiratory 0.92 0.845 – 1 0.0536 592 5881 all phecode
472 Chronic pharyngitis and nasopharyngitis Respiratory 1.01 0.965 – 1.06 0.596 1797 16986 all phecode
473 Diseases of the larynx and vocal cords Respiratory 0.979 0.942 – 1.02 0.277 2983 25244 all phecode
473.1 Chronic laryngitis Respiratory 1.17 0.924 – 1.48 0.191 68 674 all phecode
473.3 Paralysis/spasm of vocal cords or larynx Respiratory 1.05 0.961 – 1.14 0.304 628 6254 all phecode
473.4 Voice disturbance Respiratory 0.978 0.937 – 1.02 0.322 2336 21975 all phecode
474 Acute and chronic tonsillitis Respiratory 0.952 0.887 – 1.02 0.167 880 7892 all phecode
474.1 Acute tonsillitis Respiratory 0.929 0.83 – 1.04 0.202 335 3181 all phecode
474.2 Chronic tonsillitis and adenoiditis Respiratory 0.96 0.888 – 1.04 0.301 700 6445 all phecode
475 Chronic sinusitis Respiratory 1.01 0.98 – 1.05 0.451 4378 27891 all phecode
475.9 Postnasal drip Respiratory 0.978 0.913 – 1.05 0.514 922 9017 all phecode
476 Allergic rhinitis Respiratory 1 0.982 – 1.03 0.741 12687 28117 all phecode
477 Epistaxis or throat hemorrhage Respiratory 0.991 0.933 – 1.05 0.783 1150 11318 all phecode
478 Throat pain Respiratory 0.966 0.874 – 1.07 0.494 426 4195 all phecode
479 Other upper respiratory disease Respiratory 1.03 1 – 1.06 0.0319 5627 28048 all phecode
480 Pneumonia Respiratory 1.02 0.995 – 1.05 0.113 5947 37034 all phecode
480.1 Bacterial pneumonia Respiratory 0.955 0.898 – 1.02 0.145 1155 11495 all phecode
480.11 Pneumococcal pneumonia Respiratory 0.941 0.862 – 1.03 0.178 568 5644 all phecode
480.12 Pseudomonal pneumonia Respiratory 0.955 0.809 – 1.13 0.589 153 1523 all phecode
480.13 MRSA pneumonia Respiratory 1.03 0.85 – 1.24 0.777 117 1165 all phecode
480.2 Viral pneumonia Respiratory 1.06 0.916 – 1.22 0.454 202 1992 all phecode
480.3 Pneumonia due to fungus (mycoses) Respiratory 1.02 0.862 – 1.2 0.844 159 1590 all phecode
480.5 Bronchopneumonia and lung abscess Respiratory 0.932 0.784 – 1.11 0.423 135 1312 all phecode
481 Influenza Respiratory 1.04 0.979 – 1.1 0.215 1355 13284 all phecode
483 Acute bronchitis and bronchiolitis Respiratory 0.987 0.952 – 1.02 0.492 3412 29871 all phecode
495 Asthma Respiratory 1.04 1.01 – 1.06 0.00441 8671 33569 all phecode
495.1 Chronic obstructive asthma Respiratory 1.04 0.94 – 1.16 0.42 397 3925 all phecode
495.11 Chronic obstructive asthma with exacerbation Respiratory 1.05 0.829 – 1.32 0.697 81 802 all phecode
495.2 Asthma with exacerbation Respiratory 1 0.949 – 1.05 0.989 1629 16033 all phecode
496 Chronic airway obstruction Respiratory 1.11 1.08 – 1.14 1.77e-11 5343 28343 all phecode
496.1 Emphysema Respiratory 1.12 1.07 – 1.17 1.07e-06 2134 19414 all phecode
496.2 Chronic bronchitis Respiratory 1.12 1.08 – 1.16 7.01e-11 4128 26624 all phecode
496.21 Obstructive chronic bronchitis Respiratory 1.13 1.09 – 1.17 1.2e-11 3747 25467 all phecode
496.3 Bronchiectasis Respiratory 0.997 0.912 – 1.09 0.952 549 5453 all phecode
497 Bronchitis Respiratory 1.03 0.984 – 1.08 0.198 1946 18824 all phecode
498 Acute bronchospasm Respiratory 1.03 0.938 – 1.13 0.526 496 4943 all phecode
499 Cystic fibrosis Respiratory 0.928 0.787 – 1.09 0.374 151 1510 all phecode
500 Lung disease due to external agents Respiratory 0.984 0.901 – 1.08 0.725 557 5551 all phecode
500.1 Extrinsic allergic alveolitis Respiratory 1.15 0.93 – 1.42 0.198 92 920 all phecode
500.2 Pneumoconiosis Respiratory 0.879 0.695 – 1.11 0.282 78 764 all phecode
501 Pneumonitis due to inhalation of food or vomitus Respiratory 1 0.926 – 1.09 0.909 634 6225 all phecode
502 Postinflammatory pulmonary fibrosis Respiratory 1.05 0.974 – 1.13 0.209 815 8076 all phecode
503 Pulmonary congestion and hypostasis Respiratory 0.956 0.889 – 1.03 0.222 835 8243 all phecode
504 Other alveolar and parietoalveolar pneumonopathy Respiratory 1.03 0.948 – 1.13 0.462 595 5878 all phecode
504.1 Idiopathic fibrosing alveolitis Respiratory 1.03 0.914 – 1.16 0.635 311 3084 all phecode
505 Other pulmonary inflamation or edema Respiratory 1.03 0.981 – 1.09 0.226 1638 15749 all phecode
506 Empyema and pneumothorax Respiratory 1.01 0.973 – 1.05 0.568 2894 25235 all phecode
507 Pleurisy; pleural effusion Respiratory 1.03 0.986 – 1.07 0.211 2916 26208 all phecode
508
Pulmonary collapse; interstitial and
Pulmonary collapse; interstitial and compensatory emphysema
 Respiratory 1.03 0.992 – 1.08 0.116 2382 22588 all phecode
509 Respiratory failure, insufficiency, arrest Respiratory 1.04 1.01 – 1.08 0.0164 4032 29477 all phecode
509.1 Respiratory failure Respiratory 1.02 0.976 – 1.07 0.346 1937 18949 all phecode
509.2 Respiratory insufficiency Respiratory 0.973 0.916 – 1.03 0.385 1174 11679 all phecode
509.3
Pulmonary insufficiency or respiratory failure
Pulmonary insufficiency or respiratory failure following trauma and surgery
 Respiratory 1.06 1.01 – 1.12 0.0225 1689 16489 all phecode
509.8
Dependence on respirator [Ventilator] or
Dependence on respirator [Ventilator] or supplemental oxygen
 Respiratory 1.04 0.985 – 1.09 0.172 1741 17249 all phecode
510 Other diseases of lung Respiratory 1.03 0.998 – 1.06 0.0699 5503 35907 all phecode
510.2 Lung transplant Respiratory 0.972 0.832 – 1.13 0.716 176 1757 all phecode
512 Other symptoms of respiratory system Respiratory 1.02 1 – 1.04 0.0435 18621 28154 all phecode
512.1 Wheezing Respiratory 1.02 0.968 – 1.08 0.416 1409 13516 all phecode
512.2 Painful respiration Respiratory 1.07 1.03 – 1.12 0.00196 2309 21263 all phecode
512.3 Abnormal chest sounds Respiratory 0.996 0.884 – 1.12 0.951 291 2845 all phecode
512.7 Shortness of breath Respiratory 1.04 1.02 – 1.07 0.000303 10034 28081 all phecode
512.8 Cough Respiratory 1.02 0.991 – 1.04 0.218 9501 28148 all phecode
512.9 Other dyspnea Respiratory 1.02 1 – 1.05 0.0497 10804 28104 all phecode
513 Respiratory abnormalities Respiratory 1.02 1 – 1.05 0.026 12932 33822 all phecode
513.3 Hypoventilation Respiratory 0.98 0.913 – 1.05 0.582 880 8646 all phecode
513.31 Apnea Respiratory 0.972 0.882 – 1.07 0.558 462 4607 all phecode
513.32 Orthopnea Respiratory 1.04 0.906 – 1.2 0.554 220 2160 all phecode
513.4 Hyperventilation Respiratory 1.09 0.99 – 1.19 0.0804 515 5124 all phecode
513.8 Disorders of diaphragm Respiratory 0.881 0.773 – 1 0.0591 258 2557 all phecode
514 Abnormal findings examination of lungs Respiratory 1.01 0.985 – 1.04 0.327 5365 34834 all phecode
514.1
Abnormal results of function study of pulmonary
Abnormal results of function study of pulmonary system
 Respiratory 1.12 0.981 – 1.27 0.0957 258 2580 all phecode
514.2 Solitary pulmonary nodule Respiratory 1.01 0.977 – 1.05 0.455 3018 27338 all phecode
516 Abnormal sputum Respiratory 1.01 0.933 – 1.09 0.848 735 7332 all phecode
516.1 Hemoptysis Respiratory 1.01 0.929 – 1.1 0.804 611 6080 all phecode
519
Other diseases of respiratory system, not
Other diseases of respiratory system, not elsewhere classified
 Respiratory 1.03 0.998 – 1.05 0.068 6458 39057 all phecode
519.1 Tracheostomy complications Respiratory 1.06 0.916 – 1.23 0.436 214 2136 all phecode
519.2 Respiratory complications Respiratory 1.04 0.943 – 1.15 0.42 445 4430 all phecode
519.8 Other diseases of respiratory system, NEC Respiratory 1.02 0.97 – 1.08 0.424 1588 15787 all phecode
519.9
Symptoms involving respiratory system and other
Symptoms involving respiratory system and other chest symptoms
 Respiratory 1.03 0.995 – 1.06 0.0985 4706 34489 all phecode
520 Disorders of tooth development Digestive 1.09 0.976 – 1.21 0.127 369 3690 all phecode
520.1 Hereditary disturbances in tooth structure Digestive 1.11 0.942 – 1.31 0.208 165 1642 all phecode
520.2 Disturbances in tooth eruption Digestive 1.1 0.956 – 1.26 0.183 218 2172 all phecode
521 Diseases of hard tissues of teeth Digestive 1.12 1.04 – 1.2 0.00159 898 8954 all phecode
521.1 Dental caries Digestive 1.12 1.04 – 1.2 0.00234 837 8349 all phecode
521.2 Dental abrasion, erosion and attrition Digestive 1.06 0.8 – 1.41 0.681 52 510 all phecode
522 Diseases of pulp and periapical tissues Digestive 1.05 0.964 – 1.15 0.252 535 5340 all phecode
522.5 Periapical abscess Digestive 1.06 0.967 – 1.17 0.204 459 4583 all phecode
523 Gingival and periodontal diseases Digestive 1.08 0.996 – 1.16 0.0619 718 7180 all phecode
523.1 Gingivitis Digestive 0.968 0.816 – 1.15 0.71 142 1418 all phecode
523.3 Periodontitis (acute or chronic) Digestive 1.11 1 – 1.24 0.0491 364 3636 all phecode
523.31 Acute periodontitis Digestive 1.1 0.979 – 1.24 0.109 311 3109 all phecode
523.32 Chronic periodontitis Digestive 1.04 0.869 – 1.25 0.643 122 1204 all phecode
524 Dentofacial anomalies, including malocclusion Digestive 0.913 0.82 – 1.02 0.098 363 3630 all phecode
524.3 Anomalies of tooth position/malocclusion Digestive 0.898 0.782 – 1.03 0.128 220 2200 all phecode
525
Other diseases of the teeth and supporting
Other diseases of the teeth and supporting structures
 Digestive 1.04 0.974 – 1.11 0.255 1039 10382 all phecode
525.1 Loss of teeth or edentulism Digestive 1.05 0.942 – 1.17 0.377 374 3731 all phecode
526 Diseases of the jaws Digestive 0.996 0.957 – 1.04 0.861 2680 26455 all phecode
526.1 Cysts of the jaws Digestive 0.992 0.869 – 1.13 0.911 247 2470 all phecode
526.3 Anomalies of jaw size/symmetry Digestive 0.899 0.788 – 1.03 0.112 241 2383 all phecode
526.4 Temporomandibular joint disorders Digestive 1.03 0.976 – 1.09 0.283 1504 15025 all phecode
526.41 Temporomandibular joint disorder, unspecified Digestive 1.04 0.979 – 1.1 0.208 1187 11858 all phecode
526.42 Arthralgia/ankylosis of temporomandibular joint Digestive 1 0.93 – 1.08 0.941 741 7400 all phecode
526.5 Inflammatory conditions of jaw Digestive 0.966 0.855 – 1.09 0.581 287 2864 all phecode
526.8 Exostosis of jaw Digestive 0.802 0.608 – 1.06 0.118 53 521 all phecode
526.9 Jaw disease NOS Digestive 0.977 0.887 – 1.07 0.628 487 4867 all phecode
527 Diseases of the salivary glands Digestive 0.996 0.948 – 1.05 0.869 1781 17771 all phecode
527.1 Hypertrophy of salivary gland Digestive 0.881 0.672 – 1.15 0.359 58 579 all phecode
527.2 Sialoadenitis Digestive 0.877 0.79 – 0.975 0.0152 394 3936 all phecode
527.7 Disturbance of salivary secretion Digestive 1.02 0.958 – 1.1 0.482 952 9481 all phecode
527.8 Other specified diseases of the salivary glands Digestive 1.04 0.909 – 1.18 0.595 254 2540 all phecode
528
Diseases of the oral soft tissues, excluding
Diseases of the oral soft tissues, excluding lesions specific for gingiva and tongue
 Digestive 0.964 0.926 – 1 0.074 2643 26197 all phecode
528.1 Stomatitis and mucositis Digestive 0.925 0.853 – 1 0.0583 668 6657 all phecode
528.11 Stomatitis and mucositis (ulcerative) Digestive 0.93 0.806 – 1.07 0.317 211 2110 all phecode
528.12 Oral aphthae Digestive 0.984 0.857 – 1.13 0.824 215 2137 all phecode
528.3 Cellulitis and abscess of oral soft tissues Digestive 0.876 0.765 – 1 0.0549 235 2338 all phecode
528.4 Cysts of oral soft tissues Digestive 0.93 0.772 – 1.12 0.45 124 1229 all phecode
528.41 Cyst of the salivary gland Digestive 0.917 0.725 – 1.16 0.469 77 760 all phecode
528.5 Diseases of lips Digestive 0.925 0.84 – 1.02 0.112 462 4602 all phecode
528.6 Leukoplakia of oral mucosa Digestive 0.903 0.759 – 1.07 0.248 137 1370 all phecode
528.7 Sialolithiasis Digestive 0.943 0.8 – 1.11 0.482 163 1623 all phecode
529 Diseases and other conditions of the tongue Digestive 0.996 0.921 – 1.08 0.919 690 6878 all phecode
529.1 Glossitis Digestive 1.01 0.849 – 1.21 0.888 129 1281 all phecode
529.6 Glossodynia Digestive 1.01 0.863 – 1.19 0.88 168 1652 all phecode
530 Diseases of esophagus Digestive 1.09 1.06 – 1.11 2.14e-16 17081 27931 all phecode
530.1 Esophagitis, GERD and related diseases Digestive 1.09 1.07 – 1.11 6.01e-17 16572 27931 all phecode
530.11 GERD Digestive 1.09 1.07 – 1.11 2.03e-17 16143 27929 all phecode
530.12 Ulcer of esophagus Digestive 1.18 1.06 – 1.31 0.00279 400 3983 all phecode
530.13 Barrett's esophagus Digestive 1.09 1.01 – 1.18 0.0209 762 7584 all phecode
530.14 Reflux esophagitis Digestive 1.1 1.04 – 1.15 0.000203 1900 17495 all phecode
530.15 Eosinophilic esophagitis Digestive 1.15 1 – 1.33 0.0501 221 2210 all phecode
530.2 Esophageal bleeding (varices/hemorrhage) Digestive 1.04 0.962 – 1.13 0.306 651 6473 all phecode
530.3 Stricture and stenosis of esophagus Digestive 1.06 0.989 – 1.14 0.0992 911 8971 all phecode
530.5 Disorders of esophageal motility Digestive 1.03 0.946 – 1.13 0.467 548 5432 all phecode
530.6 Diverticulum of esophagus, acquired Digestive 1.02 0.846 – 1.23 0.845 129 1265 all phecode
530.7 Gastroesophageal laceration-hemorrhage syndrome Digestive 0.954 0.769 – 1.19 0.673 82 812 all phecode
530.9 Heartburn Digestive 1.05 0.99 – 1.1 0.107 1519 14928 all phecode
531 Peptic ulcer (excl. esophageal) Digestive 1.06 1.01 – 1.11 0.0173 2073 20617 all phecode
531.1 Hemorrhage from gastrointestinal ulcer Digestive 1.01 0.911 – 1.12 0.853 391 3883 all phecode
531.2 Gastric ulcer Digestive 1.05 0.986 – 1.11 0.137 1201 11970 all phecode
531.3 Duodenal ulcer Digestive 1.04 0.946 – 1.14 0.421 467 4640 all phecode
531.4 Peptic ulcer, site unspecified Digestive 1.07 0.99 – 1.15 0.0899 804 8018 all phecode
531.5 Gastrojejunal ulcer Digestive 1.09 0.925 – 1.3 0.292 150 1500 all phecode
532 Dysphagia Digestive 1.06 1.03 – 1.1 5.31e-05 5585 26852 all phecode
535 Gastritis and duodenitis Digestive 1.07 1.03 – 1.12 0.000358 2799 27335 all phecode
535.1 Acute gastritis Digestive 1.04 0.983 – 1.11 0.161 1178 11750 all phecode
535.2 Atrophic gastritis Digestive 1.08 0.963 – 1.21 0.191 344 3413 all phecode
535.6 Duodenitis Digestive 1.12 0.997 – 1.25 0.0565 334 3337 all phecode
535.8 Other specified gastritis Digestive 1.06 0.979 – 1.15 0.15 638 6354 all phecode
535.9 Gastritis and duodenitis, NOS Digestive 1.07 1.01 – 1.13 0.0277 1255 12511 all phecode
536 Disorders of function of stomach Digestive 1.05 1.01 – 1.09 0.0146 2911 27685 all phecode
536.3 Gastroparesis Digestive 1.13 1.05 – 1.23 0.00197 706 6901 all phecode
536.7
Complications of gastrostomy, colostomy and
Complications of gastrostomy, colostomy and enterostomy
 Digestive 1.02 0.919 – 1.13 0.726 407 4059 all phecode
536.8
Dyspepsia and other specified disorders of
Dyspepsia and other specified disorders of function of stomach
 Digestive 1.03 0.989 – 1.08 0.142 2150 21094 all phecode
537 Other disorders of stomach and duodenum Digestive 1.08 1.04 – 1.12 6.96e-05 3183 30048 all phecode
537.1 Lesions of stomach and duodenum Digestive 1.2 1.03 – 1.4 0.0213 173 1725 all phecode
539 Bariatric surgery Digestive 1.08 1.02 – 1.14 0.00444 1509 15074 all phecode
540 Appendiceal conditions Digestive 0.996 0.908 – 1.09 0.932 495 4948 all phecode
540.1 Appendicitis Digestive 0.992 0.899 – 1.1 0.88 425 4239 all phecode
540.11 Acute appendicitis Digestive 0.983 0.881 – 1.1 0.761 353 3511 all phecode
550 Abdominal hernia Digestive 1.05 1.02 – 1.07 0.000943 6768 37731 all phecode
550.1 Inguinal hernia Digestive 0.97 0.923 – 1.02 0.237 1744 16488 all phecode
550.2 Diaphragmatic hernia Digestive 1.07 1.03 – 1.11 0.00144 2817 25849 all phecode
550.3 Femoral hernia Digestive 1.02 0.857 – 1.22 0.797 131 1291 all phecode
550.4 Umbilical hernia Digestive 1.06 0.997 – 1.12 0.0637 1313 13110 all phecode
550.5 Ventral hernia Digestive 1.08 1.03 – 1.12 0.00113 2241 22163 all phecode
550.6 Incisional hernia Digestive 1.01 0.953 – 1.07 0.745 1313 13111 all phecode
555
Inflammatory bowel disease and other
Inflammatory bowel disease and other gastroenteritis and colitis
 Digestive 1.08 1.02 – 1.14 0.00439 1536 15153 all phecode
555.1 Regional enteritis Digestive 1.07 0.999 – 1.14 0.0549 919 9095 all phecode
555.2 Ulcerative colitis Digestive 1.07 0.998 – 1.14 0.056 937 9315 all phecode
555.21 Ulcerative colitis (chronic) Digestive 1.08 0.991 – 1.19 0.0773 537 5315 all phecode
556 Ulceration of the lower GI tract Digestive 1.04 0.957 – 1.13 0.358 632 6267 all phecode
556.1 Ulceration of intestine Digestive 1.07 0.98 – 1.17 0.133 551 5451 all phecode
556.11
Angiodysplasia of intestine (without mention of
Angiodysplasia of intestine (without mention of hemorrhage)
 Digestive 0.999 0.867 – 1.15 0.993 214 2093 all phecode
557 Intestinal malabsorption (non-celiac) Digestive 1.07 1.02 – 1.13 0.00863 1716 16490 all phecode
557.1 Celiac disease Digestive 1 0.905 – 1.11 0.961 421 4026 all phecode
558 Noninfectious gastroenteritis Digestive 1.1 1.06 – 1.14 3.02e-07 3458 26408 all phecode
559 Ileostomy status Digestive 1 0.938 – 1.07 0.928 957 9565 all phecode
560 Intestinal obstruction without mention of hernia Digestive 1.02 0.98 – 1.06 0.354 3004 24851 all phecode
560.1 Paralytic ileus Digestive 0.999 0.948 – 1.05 0.964 1627 15714 all phecode
560.2 Impaction of intestine Digestive 1.07 0.966 – 1.2 0.188 387 3779 all phecode
560.3 Peritoneal or intestinal adhesions Digestive 0.992 0.875 – 1.12 0.894 266 2647 all phecode
560.4 Other intestinal obstruction Digestive 0.989 0.939 – 1.04 0.664 1651 16170 all phecode
561 Symptoms involving digestive system Digestive 1.07 1.02 – 1.11 0.00215 2608 21766 all phecode
562 Diverticulosis and diverticulitis Digestive 1.02 0.989 – 1.05 0.228 6295 23431 all phecode
562.1 Diverticulosis Digestive 1.02 0.988 – 1.05 0.247 6246 23383 all phecode
562.2 Diverticulitis Digestive 1.05 1 – 1.11 0.0459 1611 15162 all phecode
564 Functional digestive disorders Digestive 1.06 1.03 – 1.08 1.74e-06 11411 28676 all phecode
564.1 Irritable Bowel Syndrome Digestive 1.09 1.06 – 1.14 1.23e-06 3457 22266 all phecode
564.9 Personal history of diseases of digestive system Digestive 1.06 1.02 – 1.1 0.00361 3074 25861 all phecode
565 Anal and rectal conditions Digestive 1.03 0.994 – 1.07 0.106 3355 30757 all phecode
565.1 Anal and rectal polyp Digestive 1.05 0.992 – 1.11 0.092 1305 12649 all phecode
567 Peritonitis and retroperitoneal infections Digestive 1.05 0.993 – 1.11 0.0865 1364 13616 all phecode
568 Other disorders of peritoneum Digestive 1.08 1.02 – 1.13 0.00477 1705 17038 all phecode
568.1
Peritoneal adhesions (postoperative)
Peritoneal adhesions (postoperative) (postinfection)
 Digestive 1.07 1.01 – 1.14 0.0168 1247 12468 all phecode
569 Other disorders of intestine Digestive 1.03 1.01 – 1.06 0.0112 8079 35231 all phecode
569.1 Toxic gastroenteritis and colitis Digestive 0.987 0.881 – 1.11 0.827 326 3260 all phecode
569.2 Gastrointestinal complications Digestive 1.02 0.968 – 1.08 0.413 1395 13933 all phecode
571 Chronic liver disease and cirrhosis Digestive 1.05 1.02 – 1.08 0.00184 4610 32562 all phecode
571.5 Other chronic nonalcoholic liver disease Digestive 1.05 1.02 – 1.09 0.00205 4342 32234 all phecode
571.51 Cirrhosis of liver without mention of alcohol Digestive 1.04 0.975 – 1.11 0.232 1018 10095 all phecode
571.6 Primary biliary cirrhosis Digestive 0.947 0.808 – 1.11 0.498 179 1790 all phecode
571.8
Liver abscess and sequelae of chronic liver
Liver abscess and sequelae of chronic liver disease
 Digestive 1.04 0.971 – 1.11 0.265 950 9498 all phecode
571.81 Portal hypertension Digestive 1.04 0.953 – 1.14 0.374 573 5730 all phecode
572 Ascites (non malignant) Digestive 1.03 0.984 – 1.07 0.219 2278 22675 all phecode
573 Other disorders of liver Digestive 1.02 0.996 – 1.05 0.094 5599 33620 all phecode
573.1 Chronic passive congestion of liver Digestive 0.929 0.783 – 1.1 0.402 136 1359 all phecode
573.2 Liver replaced by transplant Digestive 1.1 0.973 – 1.25 0.129 292 2920 all phecode
573.3 Hepatomegaly Digestive 1.12 1.02 – 1.23 0.0232 470 4700 all phecode
573.4 Acute and subacute necrosis of liver Digestive 0.966 0.858 – 1.09 0.569 316 3149 all phecode
573.5 Jaundice (not of newborn) Digestive 1.05 0.984 – 1.13 0.134 958 9496 all phecode
573.6
Nonspecific elevation of levels of transaminase
Nonspecific elevation of levels of transaminase or lactic acid dehydrogenase [LDH]
 Digestive 1.01 0.966 – 1.05 0.792 2756 26470 all phecode
573.7 Abnormal results of function study of liver Digestive 1.01 0.97 – 1.05 0.682 3018 27774 all phecode
573.9 Abnormal serum enzyme levels Digestive 1.01 0.979 – 1.04 0.52 4679 33866 all phecode
574 Cholelithiasis and cholecystitis Digestive 1.01 0.969 – 1.04 0.756 3177 30809 all phecode
574.1 Cholelithiasis Digestive 0.994 0.956 – 1.03 0.755 2924 28874 all phecode
574.11 Cholelithiasis with acute cholecystitis Digestive 0.853 0.761 – 0.956 0.00626 342 3412 all phecode
574.12 Cholelithiasis with other cholecystitis Digestive 0.94 0.861 – 1.03 0.171 553 5501 all phecode
574.2 Calculus of bile duct Digestive 0.991 0.923 – 1.06 0.796 852 8503 all phecode
574.3 Cholecystitis without cholelithiasis Digestive 0.957 0.89 – 1.03 0.23 822 8181 all phecode
575 Other biliary tract disease Digestive 1.01 0.968 – 1.06 0.612 2266 22555 all phecode
575.1 Cholangitis Digestive 0.969 0.867 – 1.08 0.58 354 3530 all phecode
575.2 Obstruction of bile duct Digestive 0.992 0.913 – 1.08 0.857 621 6201 all phecode
575.6 Cholesterolosis of gallbladder Digestive 0.954 0.826 – 1.1 0.522 207 2063 all phecode
575.7 Other disorders of gallbladder Digestive 1.02 0.952 – 1.09 0.593 939 9382 all phecode
575.8 Other disorders of biliary tract Digestive 1 0.944 – 1.07 0.914 1154 11523 all phecode
575.9
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of biliary tract
 Digestive 0.952 0.84 – 1.08 0.446 260 2600 all phecode
577 Diseases of pancreas Digestive 1 0.958 – 1.05 0.952 2225 22106 all phecode
577.1 Acute pancreatitis Digestive 1.02 0.963 – 1.08 0.468 1212 12110 all phecode
577.2 Chronic pancreatitis Digestive 1.14 1.04 – 1.26 0.00506 495 4950 all phecode
577.3 Cyst and pseudocyst of pancreas Digestive 1.02 0.938 – 1.12 0.603 570 5601 all phecode
578 Gastrointestinal hemorrhage Digestive 1.05 1.02 – 1.09 0.00147 4554 37045 all phecode
578.1 Hematemesis Digestive 1.1 1.01 – 1.21 0.0383 485 4842 all phecode
578.2 Blood in stool Digestive 1.03 0.989 – 1.07 0.15 2743 26554 all phecode
578.8 Hemorrhage of rectum and anus Digestive 1.06 1.02 – 1.11 0.00733 2210 21750 all phecode
578.9 Hemorrhage of gastrointestinal tract Digestive 1.07 1.01 – 1.13 0.0137 1562 15345 all phecode
579 Other symptoms involving abdomen and pelvis Digestive 1.04 1.01 – 1.07 0.0153 4431 34209 all phecode
579.2 Splenomegaly Digestive 1.07 0.988 – 1.15 0.0977 730 7262 all phecode
579.8 Nonspecific abnormal findings in stool contents Digestive 0.988 0.935 – 1.04 0.667 1410 13877 all phecode
580 Nephritis; nephrosis; renal sclerosis Genitourinary 1.03 0.98 – 1.08 0.246 1881 15516 all phecode
580.1 Glomerulonephritis Genitourinary 1.07 0.964 – 1.19 0.202 401 3992 all phecode
580.11 Proliferative glomerulonephritis Genitourinary 1.05 0.889 – 1.24 0.56 146 1440 all phecode
580.12 Non-proliferative glomerulonephritis Genitourinary 0.939 0.777 – 1.14 0.517 114 1128 all phecode
580.13 Acute glomerulonephritis, NOS Genitourinary 1.03 0.786 – 1.35 0.826 61 600 all phecode
580.14 Chronic glomerulonephritis, NOS Genitourinary 1.07 0.941 – 1.21 0.31 277 2760 all phecode
580.2
Nephrotic syndrome without mention of
Nephrotic syndrome without mention of glomerulonephritis
 Genitourinary 1.07 0.933 – 1.24 0.321 221 2193 all phecode
580.3
Nephritis and nephropathy without mention of
Nephritis and nephropathy without mention of glomerulonephritis
 Genitourinary 1.03 0.972 – 1.09 0.341 1502 11930 all phecode
580.31
Nephritis and nephropathy in diseases
Nephritis and nephropathy in diseases classified elsewhere
 Genitourinary 1.02 0.954 – 1.1 0.531 992 7228 all phecode
580.32
Nephritis and nephropathy with pathological
Nephritis and nephropathy with pathological lesion
 Genitourinary 1.01 0.93 – 1.09 0.873 683 6612 all phecode
580.4 Renal sclerosis, NOS Genitourinary 1.02 0.907 – 1.14 0.779 340 3400 all phecode
585 Renal failure Genitourinary 1.06 1.03 – 1.09 1.14e-05 7470 32340 all phecode
585.1 Acute renal failure Genitourinary 1.07 1.03 – 1.1 0.00013 4265 27230 all phecode
585.2 Renal failure NOS Genitourinary 1.05 0.973 – 1.12 0.226 832 8162 all phecode
585.3 Chronic renal failure [CKD] Genitourinary 1.06 1.03 – 1.1 3.69e-05 5580 29470 all phecode
585.31 Renal dialysis Genitourinary 1.04 0.961 – 1.12 0.352 747 7423 all phecode
585.32 End stage renal disease Genitourinary 1.03 0.964 – 1.1 0.383 1007 9783 all phecode
585.33 Chronic Kidney Disease, Stage III Genitourinary 1.05 1.01 – 1.09 0.0147 3209 21312 all phecode
585.34 Chronic Kidney Disease, Stage IV Genitourinary 1.03 0.966 – 1.1 0.347 977 9190 all phecode
585.4 Chronic kidney disease, Stage I or II Genitourinary 1.06 1 – 1.13 0.0455 1227 11191 all phecode
586 Other disorders of the kidney and ureters Genitourinary 1.03 1.01 – 1.06 0.0118 7628 34189 all phecode
586.1 Anatomical abnormatilies of kidney and ureters Genitourinary 1.07 0.955 – 1.2 0.245 349 3480 all phecode
586.11 Small kidney Genitourinary 1.01 0.876 – 1.17 0.865 210 2093 all phecode
586.12 Vesicoureteral reflux Genitourinary 1.18 0.986 – 1.41 0.0704 136 1360 all phecode
586.2 Cyst of kidney, acquired Genitourinary 0.993 0.939 – 1.05 0.818 1381 12912 all phecode
586.3 Vascular disorders of kidney/hypertrophy Genitourinary 0.93 0.799 – 1.08 0.347 187 1862 all phecode
586.4 Stricture/obstruction of ureter Genitourinary 0.987 0.94 – 1.04 0.611 1821 17115 all phecode
587 Kidney replaced by transpant Genitourinary 1 0.931 – 1.08 0.96 819 8134 all phecode
588 Disorders resulting from impaired renal function Genitourinary 1.02 0.957 – 1.09 0.503 976 9389 all phecode
588.1 Renal osteodystrophy Genitourinary 1.06 0.935 – 1.19 0.38 290 2900 all phecode
588.2 Secondary hyperparathyroidism (of renal origin) Genitourinary 1.04 0.96 – 1.12 0.366 755 7275 all phecode
589 Abnormal results of function study of kidney Genitourinary 1.04 0.977 – 1.11 0.209 1007 9834 all phecode
590 Pyelonephritis Genitourinary 1.02 0.964 – 1.07 0.527 1461 14350 all phecode
591 Urinary tract infection Genitourinary 1.03 1.01 – 1.06 0.00707 9873 32513 all phecode
592 Cystitis and urethritis Genitourinary 1.04 1 – 1.08 0.044 3038 24207 all phecode
592.1 Cystitis Genitourinary 1.04 0.997 – 1.08 0.0712 2880 23279 all phecode
592.11 Acute cystitis Genitourinary 1.01 0.961 – 1.06 0.685 1783 16452 all phecode
592.12 Chronic cystitis Genitourinary 0.974 0.848 – 1.12 0.708 239 2343 all phecode
592.13 Chronic interstitial cystitis Genitourinary 1.13 1.02 – 1.24 0.0188 431 4310 all phecode
592.2 Urethritis and urethral syndrome Genitourinary 1.1 0.955 – 1.27 0.188 210 2093 all phecode
593 Hematuria Genitourinary 1.03 0.996 – 1.06 0.0871 4859 32063 all phecode
593.1 Gross hematuria Genitourinary 1.01 0.955 – 1.06 0.802 1585 14824 all phecode
593.2 Microscopic hematuria Genitourinary 1.04 0.979 – 1.11 0.185 1049 10301 all phecode
594 Urinary calculus Genitourinary 1.04 1.01 – 1.07 0.00249 6707 38209 all phecode
594.1 Calculus of kidney Genitourinary 1.04 1.02 – 1.07 0.00147 6273 38051 all phecode
594.2 Calculus of lower urinary tract Genitourinary 0.99 0.888 – 1.1 0.856 366 3638 all phecode
594.3 Calculus of ureter Genitourinary 1.04 0.986 – 1.1 0.148 1361 13561 all phecode
594.8 Renal colic Genitourinary 1.12 1 – 1.25 0.0462 356 3560 all phecode
595 Hydronephrosis Genitourinary 1.06 1.01 – 1.12 0.0214 1670 16658 all phecode
596 Other disorders of bladder Genitourinary 1.04 0.999 – 1.08 0.0554 3074 28020 all phecode
596.1 Bladder neck obstruction Genitourinary 1.06 0.952 – 1.17 0.306 400 3942 all phecode
596.5 Functional disorders of bladder Genitourinary 1.04 0.988 – 1.09 0.138 1719 17049 all phecode
597 Other disorders of urethra and urinary tract Genitourinary 1.04 0.984 – 1.11 0.149 1211 11998 all phecode
597.1 Urethral stricture (not specified as infectious) Genitourinary 1.1 1.01 – 1.19 0.0274 661 6537 all phecode
597.2 Urinary complications NEC Genitourinary 1.01 0.95 – 1.08 0.688 1049 10479 all phecode
597.8 Urethral hypermobility/ISD Genitourinary 1.07 0.915 – 1.24 0.414 189 1873 all phecode
598 Abnormal findings on examination of urine Genitourinary 0.98 0.822 – 1.17 0.823 138 1356 all phecode
598.4 Other cells and casts in urine Genitourinary 0.95 0.79 – 1.14 0.587 122 1192 all phecode
599 Other symptoms/disorders or the urinary system Genitourinary 1.02 1 – 1.05 0.0238 14168 30681 all phecode
599.1 Urinary obstruction Genitourinary 0.964 0.893 – 1.04 0.35 728 6861 all phecode
599.2 Retention of urine Genitourinary 1 0.974 – 1.04 0.772 5034 28305 all phecode
599.3 Dysuria Genitourinary 1.03 0.998 – 1.06 0.0669 4397 27849 all phecode
599.4 Urinary incontinence Genitourinary 1.04 1.01 – 1.07 0.00562 5599 26960 all phecode
599.5 Frequency of urination and polyuria Genitourinary 1.03 0.999 – 1.06 0.0562 5498 28723 all phecode
599.6 Oliguria and anuria Genitourinary 1.06 0.971 – 1.15 0.204 599 5902 all phecode
599.7 Urethral discharge Genitourinary 0.947 0.783 – 1.14 0.57 118 1175 all phecode
599.8 Other symptoms involving urinary system Genitourinary 1.01 0.98 – 1.04 0.521 5446 27963 all phecode
599.9 Other abnormality of urination Genitourinary 1.03 0.996 – 1.07 0.0814 3041 24877 all phecode
600 Hyperplasia of prostate Genitourinary 0.986 0.948 – 1.02 0.461 4063 11364 all phecode
601 Inflammatory diseases of prostate Genitourinary 0.965 0.905 – 1.03 0.285 1044 9665 all phecode
601.1 Prostatitis Genitourinary 0.959 0.872 – 1.06 0.394 477 4596 all phecode
601.11 Acute prostatitis Genitourinary 0.905 0.76 – 1.08 0.266 124 1200 all phecode
601.12 Chronic prostatitis Genitourinary 1.11 0.887 – 1.38 0.367 95 943 all phecode
601.3 Orchitis and epididymitis Genitourinary 1.01 0.909 – 1.12 0.866 389 3822 all phecode
601.4 Balanoposthitis Genitourinary 0.997 0.832 – 1.19 0.974 127 1224 all phecode
601.8
Other inflammatory disorders of male genital
Other inflammatory disorders of male genital organs
 Genitourinary 0.932 0.793 – 1.09 0.39 161 1591 all phecode
602 Other disorders of prostate Genitourinary 0.932 0.837 – 1.04 0.199 361 3399 all phecode
602.3 Dysplasia of prostate Genitourinary 0.883 0.698 – 1.12 0.3 77 730 all phecode
603 Other disorders of testis Genitourinary 0.944 0.854 – 1.04 0.256 440 4354 all phecode
603.1 Hydrocele Genitourinary 0.988 0.874 – 1.12 0.851 293 2882 all phecode
603.2 Spermatocele Genitourinary 0.92 0.779 – 1.09 0.329 156 1539 all phecode
604 Disorders of penis Genitourinary 1.03 0.947 – 1.11 0.539 685 6748 all phecode
604.1 Redundant prepuce and phimosis/BXO Genitourinary 1.06 0.897 – 1.26 0.481 155 1540 all phecode
604.3 Peyronie's disease Genitourinary 1.01 0.882 – 1.17 0.84 215 2132 all phecode
605 Erectile dysfunction [ED] Genitourinary 0.973 0.937 – 1.01 0.148 3776 12700 all phecode
608 Other disorders of male genital organs Genitourinary 1 0.953 – 1.06 0.894 1645 13758 all phecode
609 Male infertility and abnormal spermatozoa Genitourinary 0.961 0.87 – 1.06 0.427 424 4196 all phecode
609.1 Infertility, male Genitourinary 0.987 0.877 – 1.11 0.831 302 2992 all phecode
609.11 Azoospermia and oligospermia Genitourinary 0.97 0.782 – 1.2 0.785 95 950 all phecode
609.2 Abnormal spermatozoa Genitourinary 0.878 0.743 – 1.04 0.127 154 1519 all phecode
610 Benign mammary dysplasias Genitourinary 0.98 0.945 – 1.02 0.291 3683 16548 all phecode
610.1 Cystic mastopathy Genitourinary 1.01 0.957 – 1.06 0.755 1633 14191 all phecode
610.2 Fibroadenosis of breast Genitourinary 1.06 0.812 – 1.38 0.673 60 600 all phecode
610.4 Benign neoplasm of breast Genitourinary 0.957 0.919 – 0.997 0.0344 2837 16430 all phecode
610.8 Other specified benign mammary dysplasias Genitourinary 0.987 0.931 – 1.05 0.671 1269 12191 all phecode
611 Abnormal findings on mammogram or breast exam Genitourinary 0.966 0.937 – 0.995 0.0215 6067 18690 all phecode
611.1 Abnormal mammogram Genitourinary 0.954 0.923 – 0.985 0.00436 4980 16120 all phecode
611.11 Mammographic microcalcification Genitourinary 0.915 0.859 – 0.975 0.0057 1122 10394 all phecode
611.3 Lump or mass in breast Genitourinary 0.978 0.942 – 1.01 0.227 3549 18572 all phecode
612
Breast conditions, congenital or relating to
Breast conditions, congenital or relating to hormones
 Genitourinary 0.984 0.922 – 1.05 0.617 1051 10425 all phecode
612.1 Galactorrhea Genitourinary 1.18 0.989 – 1.41 0.0663 139 1390 all phecode
612.2 Hypertrophy of breast (Gynecomastia) Genitourinary 0.967 0.898 – 1.04 0.37 800 7962 all phecode
612.3 Congenital anomalies of breast Genitourinary 0.897 0.717 – 1.12 0.345 83 810 all phecode
613 Other nonmalignant breast conditions Genitourinary 0.984 0.951 – 1.02 0.372 3897 22072 all phecode
613.1 Inflammatory disease of breast Genitourinary 0.979 0.9 – 1.07 0.631 593 5874 all phecode
613.5 Mastodynia Genitourinary 0.998 0.948 – 1.05 0.928 1675 16203 all phecode
613.7 Other signs and symptoms in breast Genitourinary 0.991 0.924 – 1.06 0.807 883 8754 all phecode
613.8 Other specified disorders of breast Genitourinary 0.963 0.899 – 1.03 0.274 932 9248 all phecode
613.9 Breast disorder NOS Genitourinary 0.999 0.946 – 1.06 0.972 1465 14174 all phecode
614 Inflammatory diseases of female pelvic organs Genitourinary 1.02 0.988 – 1.06 0.199 3715 19647 all phecode
614.1
Pelvic peritoneal adhesions, female
Pelvic peritoneal adhesions, female (postoperative) (postinfection)
 Genitourinary 1.07 0.953 – 1.19 0.263 337 3370 all phecode
614.3 Pelvic inflammatory disease (PID) Genitourinary 1.03 0.94 – 1.14 0.487 478 4773 all phecode
614.31 Acute inflammatory pelvic disease Genitourinary 1.08 0.873 – 1.33 0.492 94 933 all phecode
614.32 Chronic inflammatory pelvic disease Genitourinary 1.05 0.9 – 1.22 0.543 186 1842 all phecode
614.33 Pelvic inflammatory disease, NOS Genitourinary 1.11 0.968 – 1.27 0.138 246 2460 all phecode
614.4 Inflammatory diseases of uterus, except cervix Genitourinary 1.09 0.921 – 1.29 0.318 165 1639 all phecode
614.5
Inflammatory disease of cervix, vagina, and
Inflammatory disease of cervix, vagina, and vulva
 Genitourinary 1.02 0.977 – 1.05 0.444 3180 19539 all phecode
614.51 Cervicitis and endocervicitis Genitourinary 0.964 0.85 – 1.09 0.569 264 2640 all phecode
614.52 Vaginitis and vulvovaginitis Genitourinary 1.02 0.979 – 1.06 0.35 2732 18924 all phecode
614.53 Cyst or abscess of Bartholin's gland Genitourinary 1.16 0.971 – 1.39 0.102 132 1311 all phecode
614.54 Abscess or ulceration of vulva Genitourinary 1.02 0.882 – 1.17 0.834 225 2244 all phecode
615 Endometriosis Genitourinary 1.07 1.01 – 1.13 0.0129 1585 14666 all phecode
618 Genital prolapse Genitourinary 1.03 0.98 – 1.07 0.266 2079 17915 all phecode
618.1 Prolapse of vaginal walls Genitourinary 1.01 0.954 – 1.07 0.769 1408 13456 all phecode
618.2 Uterine/Uterovaginal prolapse Genitourinary 0.983 0.898 – 1.08 0.701 542 5390 all phecode
618.5 Prolapse of vaginal vault after hysterectomy Genitourinary 1.09 0.968 – 1.22 0.156 317 3162 all phecode
618.6 Vaginal enterocele, congenital or acquired Genitourinary 1.23 1.12 – 1.36 3.05e-05 441 4394 all phecode
619 Noninflammatory female genital disorders Genitourinary 0.98 0.951 – 1.01 0.197 5728 18687 all phecode
619.1
Noninflammatory disorders of ovary, fallopian
Noninflammatory disorders of ovary, fallopian tube, and broad ligament
 Genitourinary 0.968 0.912 – 1.03 0.28 1233 12082 all phecode
619.2 Disorders of uterus, NEC Genitourinary 1.05 0.97 – 1.15 0.214 591 5897 all phecode
619.3 Noninflammatory disorders of cervix Genitourinary 0.968 0.881 – 1.06 0.496 483 4823 all phecode
619.4 Noninflammatory disorders of vagina Genitourinary 0.981 0.94 – 1.02 0.364 2525 18404 all phecode
619.5 Noninflammatory disorders of vulva and perineum Genitourinary 0.976 0.919 – 1.04 0.441 1189 11717 all phecode
620 Dysplasia of female genital organs Genitourinary 1 0.903 – 1.11 0.981 395 3950 all phecode
620.1 Dysplasia of cervix Genitourinary 0.975 0.835 – 1.14 0.751 178 1780 all phecode
621 Endometrial hyperplasia Genitourinary 0.96 0.871 – 1.06 0.418 437 4370 all phecode
622 Polyp of female genital organs Genitourinary 0.989 0.936 – 1.04 0.69 1449 14264 all phecode
622.1 Polyp of corpus uteri Genitourinary 1.01 0.948 – 1.07 0.787 1132 11189 all phecode
622.2 Mucous polyp of cervix Genitourinary 0.9 0.815 – 0.994 0.0371 445 4444 all phecode
623 Hypertrophy of female genital organs Genitourinary 0.969 0.902 – 1.04 0.394 824 8165 all phecode
624 Symptoms involving female genital tract Genitourinary 1.01 0.949 – 1.06 0.857 1348 12518 all phecode
624.1 Dystrophy of female genital tract Genitourinary 1.05 0.913 – 1.22 0.47 216 2155 all phecode
624.2 Atrophy of female genital tract Genitourinary 0.923 0.702 – 1.21 0.567 64 615 all phecode
624.9 stress incontinence, female Genitourinary 1.02 0.976 – 1.07 0.337 1935 15408 all phecode
625
Pain and other symptoms associated with female
Pain and other symptoms associated with female genital organs
 Genitourinary 1 0.972 – 1.03 0.869 5653 17303 all phecode
625.1 Dyspareunia Genitourinary 1.03 0.966 – 1.09 0.411 1267 12474 all phecode
626
Disorders of menstruation and other abnormal
Disorders of menstruation and other abnormal bleeding from female genital tract
 Genitourinary 0.983 0.953 – 1.01 0.279 5940 15585 all phecode
626.1 Irregular menstrual cycle/bleeding Genitourinary 0.984 0.95 – 1.02 0.362 4315 14604 all phecode
626.11 Absent or infrequent menstruation Genitourinary 0.969 0.908 – 1.03 0.34 1062 8531 all phecode
626.12 Excessive or frequent menstruation Genitourinary 0.991 0.946 – 1.04 0.722 2097 11991 all phecode
626.13 Irregular menstrual cycle Genitourinary 1.02 0.97 – 1.07 0.463 1957 12265 all phecode
626.14 Irregular menstrual bleeding Genitourinary 0.976 0.913 – 1.04 0.471 970 8996 all phecode
626.15 Infertility, female, associated with anovulation Genitourinary 0.981 0.882 – 1.09 0.727 394 3789 all phecode
626.2 Dysmenorrhea Genitourinary 1.02 0.968 – 1.09 0.405 1373 9857 all phecode
626.4 Premenstrual tension syndromes Genitourinary 0.965 0.862 – 1.08 0.537 336 3308 all phecode
626.8 Infertility, female Genitourinary 0.924 0.858 – 0.994 0.035 817 6741 all phecode
627 Menopausal and postmenopausal disorders Genitourinary 0.985 0.952 – 1.02 0.382 4560 14557 all phecode
627.1 Postmenopausal bleeding Genitourinary 1.01 0.946 – 1.07 0.822 1146 10338 all phecode
627.2 Symptomatic menopause Genitourinary 0.982 0.944 – 1.02 0.39 3017 13763 all phecode
627.21 Symptomatic artificial menopause Genitourinary 0.835 0.704 – 0.991 0.0389 152 1514 all phecode
627.22
Need for Hormone replacement therapy
Need for Hormone replacement therapy (postmenopausal)
 Genitourinary 1.06 0.946 – 1.18 0.319 356 3513 all phecode
627.3 Postmenopausal atrophic vaginitis Genitourinary 1 0.94 – 1.07 0.901 997 9484 all phecode
627.4 Premenopausal menorrhagia Genitourinary 1.01 0.906 – 1.13 0.823 361 3580 all phecode
627.5 Premature menopause and other ovarian failure Genitourinary 0.926 0.822 – 1.04 0.201 309 3082 all phecode
628 Ovarian cyst Genitourinary 1.04 0.987 – 1.09 0.149 1945 13838 all phecode
634 Miscarriage; stillbirth Pregnancy Complications 0.948 0.883 – 1.02 0.144 826 8047 all phecode
634.1 Missed abortion/Hydatidiform mole Pregnancy Complications 0.941 0.828 – 1.07 0.354 273 2715 all phecode
634.3 Ectopic pregnancy Pregnancy Complications 0.973 0.809 – 1.17 0.771 117 1170 all phecode
635
Hemorrhage during pregnancy; childbirth and
Hemorrhage during pregnancy; childbirth and postpartum
 Pregnancy Complications 0.946 0.866 – 1.03 0.212 563 5309 all phecode
635.2
Antepartum hemorrhage, abruptio placentae, and
Antepartum hemorrhage, abruptio placentae, and placenta previa
 Pregnancy Complications 0.922 0.828 – 1.03 0.138 370 3629 all phecode
635.3 Placenta previa and abruptio placenta Pregnancy Complications 0.954 0.845 – 1.08 0.443 288 2850 all phecode
636
Early or threatened labor; hemorrhage in early
Early or threatened labor; hemorrhage in early pregnancy
 Pregnancy Complications 0.979 0.918 – 1.04 0.513 1080 7870 all phecode
636.1 Threatened premature labor Pregnancy Complications 1.01 0.91 – 1.13 0.819 380 3799 all phecode
636.2 Early onset of delivery Pregnancy Complications 0.948 0.842 – 1.07 0.374 288 2868 all phecode
636.3 Hemorrhage in early pregnancy Pregnancy Complications 0.965 0.875 – 1.06 0.482 441 4365 all phecode
636.8 Cervical incompetence Pregnancy Complications 1.17 0.919 – 1.48 0.206 77 770 all phecode
637
Short gestation; low birth weight; and fetal
Short gestation; low birth weight; and fetal growth retardation
 Pregnancy Complications 1.05 0.852 – 1.3 0.63 85 850 all phecode
642
Hypertension complicating pregnancy
Hypertension complicating pregnancy, childbirth, and the puerperium
 Pregnancy Complications 0.952 0.874 – 1.04 0.254 585 5725 all phecode
642.1 Preeclampsia and eclampsia Pregnancy Complications 0.918 0.815 – 1.03 0.156 302 3013 all phecode
643 Excessive vomiting in pregnancy Pregnancy Complications 1.09 0.954 – 1.24 0.212 252 2506 all phecode
643.1 Hyperemesis gravidarum Pregnancy Complications 1.05 0.865 – 1.26 0.645 119 1190 all phecode
644 Anemia during pregnancy Pregnancy Complications 1.11 0.973 – 1.27 0.118 224 2224 all phecode
646 Other complications of pregnancy NEC Pregnancy Complications 1.04 0.967 – 1.12 0.297 855 6531 all phecode
647
Infectious and parasitic complications
Infectious and parasitic complications affecting pregnancy
 Pregnancy Complications 1.02 0.88 – 1.17 0.822 211 2093 all phecode
647.1
Infections of genitourinary tract during
Infections of genitourinary tract during pregnancy
 Pregnancy Complications 1.16 1.01 – 1.33 0.0338 222 2213 all phecode
647.3 Major puerperal infection Pregnancy Complications 0.972 0.748 – 1.26 0.831 65 650 all phecode
649
Other conditions or status of the mother
Other conditions or status of the mother complicating pregnancy, childbirth, or the puerperium
 Pregnancy Complications 1 0.944 – 1.06 0.935 1275 8010 all phecode
649.1
Diabetes or abnormal glucose tolerance
Diabetes or abnormal glucose tolerance complicating pregnancy
 Pregnancy Complications 1.06 0.976 – 1.15 0.164 649 5687 all phecode
653
Problems associated with amniotic cavity and
Problems associated with amniotic cavity and membranes
 Pregnancy Complications 1.02 0.94 – 1.11 0.59 587 5463 all phecode
654.1
Abnormality of organs and soft tissues of
Abnormality of organs and soft tissues of pelvis complicating pregnancy, childbirth, or the puerperium
 Pregnancy Complications 1.05 0.912 – 1.21 0.494 207 2055 all phecode
654.2 Rhesus isoimmunization in pregnancy Pregnancy Complications 0.963 0.835 – 1.11 0.601 204 2040 all phecode
655
Known or suspected fetal abnormality affecting
Known or suspected fetal abnormality affecting management of mother
 Pregnancy Complications 0.964 0.914 – 1.02 0.176 1624 10064 all phecode
655.1 Abnormality in fetal heart rate or rhythm Pregnancy Complications 0.942 0.866 – 1.02 0.16 616 5533 all phecode
656 Other perinatal conditions of fetus or newborn Pregnancy Complications 1 0.934 – 1.07 0.969 898 7014 all phecode
656.2 Respiratory conditions of fetus and newborn Pregnancy Complications 1.16 0.906 – 1.49 0.238 66 660 all phecode
669 Complications of labor and delivery NEC Pregnancy Complications 0.98 0.914 – 1.05 0.571 887 6802 all phecode
671
Venous/cerebrovascular complications embolism
Venous/cerebrovascular complications embolism in pregnancy and the puerperium
 Pregnancy Complications 0.921 0.805 – 1.05 0.234 236 2351 all phecode
674 Other complications of the puerperium NEC Pregnancy Complications 1.14 0.966 – 1.35 0.12 158 1580 all phecode
676
Other disorders of the breast associated with
Other disorders of the breast associated with childbirth and disorders of lactation
 Pregnancy Complications 0.92 0.792 – 1.07 0.279 184 1814 all phecode
681 Superficial cellulitis and abscess Dermatologic 0.994 0.968 – 1.02 0.685 6500 38394 all phecode
681.1 Cellulitis and abscess of fingers/toes Dermatologic 0.955 0.9 – 1.01 0.124 1256 11462 all phecode
681.2 Cellulitis and abscess of face/neck Dermatologic 0.993 0.931 – 1.06 0.832 1007 9981 all phecode
681.3 Cellulitis and abscess of arm/hand Dermatologic 0.987 0.943 – 1.03 0.566 2123 19952 all phecode
681.5 Cellulitis and abscess of leg, except foot Dermatologic 0.979 0.937 – 1.02 0.336 2252 20944 all phecode
681.6 Cellulitis and abscess of foot, toe Dermatologic 0.997 0.95 – 1.05 0.908 1820 16893 all phecode
681.7 Cellulitis and abscess of trunk Dermatologic 1.09 1.03 – 1.15 0.002 1572 15588 all phecode
686
Other local infections of skin and subcutaneous
Other local infections of skin and subcutaneous tissue
 Dermatologic 1.05 1 – 1.1 0.0313 2257 21750 all phecode
686.1 Carbuncle and furuncle Dermatologic 1.04 0.951 – 1.14 0.389 558 5504 all phecode
686.2 Impetigo Dermatologic 1.03 0.928 – 1.13 0.617 414 4117 all phecode
686.3 Pilonidal cyst Dermatologic 0.952 0.811 – 1.12 0.547 160 1594 all phecode
686.4 Pyogenic granuloma Dermatologic 1.1 0.934 – 1.3 0.246 158 1570 all phecode
686.5 Pyoderma Dermatologic 1.13 0.864 – 1.47 0.375 63 630 all phecode
687 Symptoms affecting skin Dermatologic 1.01 0.963 – 1.07 0.625 1690 16343 all phecode
687.1 Rash and other nonspecific skin eruption Dermatologic 0.997 0.971 – 1.02 0.809 7007 34623 all phecode
687.3 Changes in skin texture Dermatologic 1.02 0.921 – 1.13 0.714 415 4121 all phecode
687.4 Disturbance of skin sensation Dermatologic 1.04 1.02 – 1.07 0.00177 6375 34216 all phecode
689 Disorder of skin and subcutaneous tissue NOS Dermatologic 0.978 0.955 – 1 0.0593 9311 37335 all phecode
690 Erythematosquamous dermatosis Dermatologic 0.958 0.93 – 0.988 0.00571 5184 31581 all phecode
690.1 Seborrheic dermatitis Dermatologic 0.958 0.929 – 0.987 0.00515 5174 31553 all phecode
691 Congenital anomalies of skin Dermatologic 1.01 0.925 – 1.11 0.81 541 5337 all phecode
691.3 Congenital pigmentary anomalies of skin Dermatologic 0.89 0.681 – 1.16 0.391 62 613 all phecode
694 Dyschromia and Vitiligo Dermatologic 0.968 0.923 – 1.02 0.194 1861 17936 all phecode
694.1 Vitiligo Dermatologic 0.95 0.793 – 1.14 0.582 137 1347 all phecode
694.2 Other dyschromia Dermatologic 0.968 0.92 – 1.02 0.213 1674 16183 all phecode
694.3 Vascular disorders of skin Dermatologic 1.17 0.937 – 1.46 0.166 82 819 all phecode
695 Erythematous conditions Dermatologic 0.992 0.959 – 1.03 0.618 4120 30247 all phecode
695.1 Toxic erythema Dermatologic 1.22 0.945 – 1.58 0.126 70 688 all phecode
695.2 Bullous dermatoses Dermatologic 1.12 0.885 – 1.41 0.351 85 805 all phecode
695.3 Rosacea Dermatologic 0.935 0.891 – 0.982 0.00752 1816 17663 all phecode
695.4 Lupus (localized and systemic) Dermatologic 1.05 0.97 – 1.14 0.223 672 6686 all phecode
695.41 Cutaneous lupus erythematosus Dermatologic 0.993 0.871 – 1.13 0.913 247 2437 all phecode
695.42 Systemic lupus erythematosus Dermatologic 1.06 0.976 – 1.15 0.163 637 6337 all phecode
695.7 Prurigo and Lichen Dermatologic 1.01 0.925 – 1.1 0.871 605 5986 all phecode
695.8 Other specified erythematous conditions Dermatologic 1.03 0.962 – 1.11 0.357 812 7980 all phecode
695.81 Erythema nodosum Dermatologic 0.787 0.596 – 1.04 0.0907 55 550 all phecode
695.9 Unspecified erythematous condition Dermatologic 1.05 0.966 – 1.13 0.273 679 6756 all phecode
696 Psoriasis and related disorders Dermatologic 1.04 0.979 – 1.1 0.22 1401 13832 all phecode
696.3 Pityriasis Dermatologic 0.975 0.779 – 1.22 0.827 92 904 all phecode
696.4 Psoriasis Dermatologic 1.04 0.985 – 1.11 0.152 1311 12976 all phecode
696.41 Psoriasis vulgaris Dermatologic 1.05 0.989 – 1.12 0.11 1200 11867 all phecode
696.42 Psoriatic arthropathy Dermatologic 1.01 0.894 – 1.15 0.827 282 2810 all phecode
697 Sarcoidosis Dermatologic 1.01 0.902 – 1.13 0.844 333 3330 all phecode
698 Pruritus and related conditions Dermatologic 1.04 0.993 – 1.08 0.101 2254 21889 all phecode
700 Corns and callosities Dermatologic 1.03 0.972 – 1.09 0.314 1373 10894 all phecode
701
Other hypertrophic and atrophic conditions of
Other hypertrophic and atrophic conditions of skin
 Dermatologic 1.01 0.983 – 1.03 0.542 7651 38050 all phecode
701.1 Keratoderma, acquired Dermatologic 1 0.918 – 1.1 0.944 567 5524 all phecode
701.2 Scar conditions and fibrosis of skin Dermatologic 0.979 0.936 – 1.02 0.353 2184 21550 all phecode
701.3 Circumscribed scleroderma Dermatologic 1.02 0.935 – 1.12 0.635 571 5660 all phecode
701.4 Keloid scar Dermatologic 0.983 0.902 – 1.07 0.69 578 5716 all phecode
701.5 Abnormal granulation tissue Dermatologic 1.05 0.947 – 1.17 0.347 400 3982 all phecode
702
Degenerative skin conditions and other
Degenerative skin conditions and other dermatoses
 Dermatologic 0.966 0.94 – 0.992 0.0116 6956 29525 all phecode
702.1 Actinic keratosis Dermatologic 0.959 0.928 – 0.992 0.0153 4171 26529 all phecode
702.2 Seborrheic keratosis Dermatologic 0.951 0.923 – 0.979 0.000853 5480 31552 all phecode
702.4 Degenerative skin disorders Dermatologic 1.08 0.868 – 1.34 0.497 86 832 all phecode
703 Diseases of nail, NOS Dermatologic 1.03 0.977 – 1.08 0.284 1650 14562 all phecode
703.1 Ingrowing nail Dermatologic 1.06 0.988 – 1.13 0.108 920 8597 all phecode
704 Diseases of hair and hair follicles Dermatologic 1.01 0.969 – 1.04 0.746 3118 29542 all phecode
704.1 Alopecia Dermatologic 1.02 0.963 – 1.08 0.541 1408 13871 all phecode
704.11 Alopecia Areata Dermatologic 0.845 0.679 – 1.05 0.131 82 811 all phecode
704.12 Telogen effluvium Dermatologic 0.895 0.686 – 1.17 0.411 63 615 all phecode
704.2 Hirsutism Dermatologic 1.01 0.896 – 1.14 0.884 299 2946 all phecode
704.8
Other specified diseases of hair and hair
Other specified diseases of hair and hair follicles
 Dermatologic 1.01 0.959 – 1.06 0.748 1752 17189 all phecode
705 Disorders of sweat glands Dermatologic 0.997 0.917 – 1.08 0.936 603 6012 all phecode
705.1 Dyshidrosis Dermatologic 0.943 0.798 – 1.11 0.487 154 1540 all phecode
705.3 Hidradenitis Dermatologic 1.04 0.91 – 1.18 0.583 245 2440 all phecode
705.8 Hyperhidrosis Dermatologic 1.03 0.967 – 1.1 0.358 1112 10986 all phecode
706 Diseases of sebaceous glands Dermatologic 0.972 0.946 – 0.999 0.0452 5995 39748 all phecode
706.1 Acne Dermatologic 0.958 0.919 – 0.999 0.0424 2594 22570 all phecode
706.2 Sebaceous cyst Dermatologic 0.983 0.945 – 1.02 0.399 2814 26819 all phecode
706.3 Seborrhea Dermatologic 0.945 0.726 – 1.23 0.674 59 582 all phecode
706.8 Other specified diseases of sebaceous glands Dermatologic 0.952 0.905 – 1 0.0612 1684 15289 all phecode
707 Chronic ulcer of skin Dermatologic 1.05 1.01 – 1.09 0.0249 2871 26816 all phecode
707.1 Decubitus ulcer Dermatologic 1.04 0.964 – 1.11 0.333 825 8119 all phecode
707.2 Chronic ulcer of leg or foot Dermatologic 1.06 0.993 – 1.13 0.0799 1108 9992 all phecode
707.3 Chronic ulcer of unspecified site Dermatologic 1.04 0.992 – 1.1 0.101 1641 16172 all phecode
709 Diffuse diseases of connective tissue Dermatologic 1.05 0.993 – 1.11 0.0846 1477 14427 all phecode
709.2 Sicca syndrome Dermatologic 1.04 0.948 – 1.14 0.408 505 4986 all phecode
709.3 Systemic sclerosis Dermatologic 0.917 0.797 – 1.06 0.229 224 2209 all phecode
709.5 Dermatomyositis Dermatologic 1.2 0.962 – 1.51 0.105 92 892 all phecode
709.6
Other specified diffuse diseases of connective
Other specified diffuse diseases of connective tissue
 Dermatologic 1.16 0.934 – 1.44 0.178 90 892 all phecode
709.7 Unspecified diffuse connective tissue disease Dermatologic 1.08 1.01 – 1.16 0.0221 917 9089 all phecode
710
Osteomyelitis, periostitis, and other
Osteomyelitis, periostitis, and other infections involving bone
 Musculoskeletal 1.04 0.976 – 1.1 0.249 1254 12103 all phecode
710.1 Osteomyelitis Musculoskeletal 1.03 0.971 – 1.1 0.314 1203 11636 all phecode
710.11 Acute osteomyelitis Musculoskeletal 1.1 1.01 – 1.2 0.031 590 5708 all phecode
710.12 Chronic osteomyelitis Musculoskeletal 1.03 0.939 – 1.12 0.557 531 5163 all phecode
710.19 Unspecified osteomyelitis Musculoskeletal 1.04 0.977 – 1.1 0.229 1153 11149 all phecode
711 Arthropathy associated with infections Musculoskeletal 1.01 0.912 – 1.12 0.835 410 4099 all phecode
711.1 Pyogenic arthritis Musculoskeletal 1.01 0.895 – 1.14 0.872 290 2900 all phecode
712 Infective connective tissue disorders Musculoskeletal 0.987 0.843 – 1.16 0.875 178 1776 all phecode
713
Arthropathy associated with other disorders
Arthropathy associated with other disorders classified elsewhere
 Musculoskeletal 1.08 0.966 – 1.22 0.171 314 3028 all phecode
713.5
Arthropathy associated with neurological
Arthropathy associated with neurological disorders
 Musculoskeletal 1.05 0.906 – 1.21 0.523 194 1824 all phecode
714
Rheumatoid arthritis and other inflammatory
Rheumatoid arthritis and other inflammatory polyarthropathies
 Musculoskeletal 1.06 1.01 – 1.11 0.0156 2086 18159 all phecode
714.1 Rheumatoid arthritis Musculoskeletal 1.07 1.01 – 1.12 0.0145 1670 15087 all phecode
714.2 Juvenile rheumatoid arthritis Musculoskeletal 0.863 0.686 – 1.09 0.209 77 767 all phecode
715 Other inflammatory spondylopathies Musculoskeletal 1.06 0.995 – 1.12 0.0741 1209 11967 all phecode
715.1 Sacroiliitis NEC Musculoskeletal 1.29 1.13 – 1.47 0.000113 262 2611 all phecode
715.2 Ankylosing spondylitis Musculoskeletal 1.08 0.938 – 1.25 0.283 219 2182 all phecode
716 Other arthropathies Musculoskeletal 1.07 1.04 – 1.09 5.13e-09 13482 31305 all phecode
716.1 Unspecified polyarthropathy or polyarthritis Musculoskeletal 1.06 0.914 – 1.23 0.433 192 1920 all phecode
716.2 Unspecified monoarthritis Musculoskeletal 0.908 0.758 – 1.09 0.297 131 1293 all phecode
716.9 Arthropathy NOS Musculoskeletal 1.07 1.04 – 1.09 6.55e-09 13410 31294 all phecode
717 Polymyalgia Rheumatica Musculoskeletal 1.09 0.96 – 1.24 0.18 261 2565 all phecode
720 Spinal stenosis Musculoskeletal 1.07 1.03 – 1.1 0.000252 3958 28539 all phecode
720.1 Spinal stenosis of lumbar region Musculoskeletal 1.04 1 – 1.08 0.0413 2872 23656 all phecode
721 Spondylosis and allied disorders Musculoskeletal 1.05 1.02 – 1.08 0.000837 5509 32391 all phecode
721.1 Spondylosis without myelopathy Musculoskeletal 1.06 1.02 – 1.09 0.00036 5153 31896 all phecode
721.2 Spondylosis with myelopathy Musculoskeletal 1.04 0.966 – 1.11 0.318 867 8629 all phecode
721.8 Other allied disorders of spine Musculoskeletal 0.974 0.856 – 1.11 0.682 262 2600 all phecode
722 Intervertebral disc disorders Musculoskeletal 1.06 1.03 – 1.09 3.54e-05 6284 34317 all phecode
722.1 Displacement of intervertebral disc Musculoskeletal 1.05 1.01 – 1.09 0.0065 3591 31411 all phecode
722.3 Schmorl's nodes Musculoskeletal 1.01 0.838 – 1.21 0.94 126 1248 all phecode
722.6 Degeneration of intervertebral disc Musculoskeletal 1.08 1.05 – 1.12 2.48e-06 3957 30744 all phecode
722.7 Intervertebral disc disorder with myelopathy Musculoskeletal 1.03 0.938 – 1.13 0.553 515 5140 all phecode
722.8 Postlaminectomy syndrome Musculoskeletal 1.13 1.02 – 1.25 0.0205 397 3968 all phecode
722.9 Other and unspecified disc disorder Musculoskeletal 1.05 0.996 – 1.1 0.0699 1932 19288 all phecode
723 Other disorders of cervical region Musculoskeletal 1.05 0.981 – 1.12 0.161 952 9495 all phecode
723.1 Torticollis Musculoskeletal 0.948 0.833 – 1.08 0.417 254 2522 all phecode
724 Other and unspecified disorders of back Musculoskeletal 1.06 1.02 – 1.09 0.000706 4130 31954 all phecode
724.1 Disorders of sacrum Musculoskeletal 1.08 1.03 – 1.12 0.00103 2307 21902 all phecode
724.2 Disorders of coccyx Musculoskeletal 1.13 1.02 – 1.25 0.0165 426 4215 all phecode
724.8 Other symptoms referable to back Musculoskeletal 1.06 0.99 – 1.13 0.0971 931 9295 all phecode
724.9 Other unspecified back disorders Musculoskeletal 1.03 0.972 – 1.09 0.34 1412 14087 all phecode
726 Peripheral enthesopathies and allied syndromes Musculoskeletal 0.991 0.969 – 1.01 0.46 9917 30176 all phecode
726.1 Enthesopathy Musculoskeletal 1.01 0.983 – 1.03 0.526 7507 30106 all phecode
726.2 Synoviopathy Musculoskeletal 1.08 1.01 – 1.15 0.0306 1015 9987 all phecode
726.3 Bursitis Musculoskeletal 0.982 0.935 – 1.03 0.478 1829 16722 all phecode
726.4 Calcaneal spur; Exostosis NOS Musculoskeletal 1.02 0.961 – 1.09 0.486 1193 11485 all phecode
727 Other disorders of synovium, tendon, and bursa Musculoskeletal 1.01 0.983 – 1.04 0.486 7425 30105 all phecode
727.1 Synovitis and tenosynovitis Musculoskeletal 1.02 0.983 – 1.06 0.279 3092 24998 all phecode
727.2 Bursitis disorders Musculoskeletal 0.885 0.799 – 0.98 0.0193 419 4112 all phecode
727.4 Ganglion and cyst of synovium, tendon, and bursa Musculoskeletal 0.972 0.919 – 1.03 0.321 1400 13621 all phecode
727.5 Rupture of synovium Musculoskeletal 0.96 0.872 – 1.06 0.41 480 4672 all phecode
727.6 Rupture of tendon, nontraumatic Musculoskeletal 1.02 0.975 – 1.06 0.424 2461 21948 all phecode
727.7 Contracture of tendon (sheath) Musculoskeletal 1.01 0.931 – 1.11 0.746 591 5893 all phecode
727.8 Plica syndrome Musculoskeletal 0.903 0.756 – 1.08 0.265 130 1264 all phecode
728 Disorders of muscle, ligament, and fascia Musculoskeletal 1.02 0.987 – 1.05 0.238 4546 29473 all phecode
728.1 Muscular calcification and ossification Musculoskeletal 1.15 0.92 – 1.43 0.221 85 843 all phecode
728.2 Laxity of ligament or hypermobility syndrome Musculoskeletal 1.04 0.919 – 1.17 0.545 297 2949 all phecode
728.7 Fasciitis Musculoskeletal 0.987 0.948 – 1.03 0.523 2814 23463 all phecode
728.71
Contracture of palmar fascia [Dupuytren's
Contracture of palmar fascia [Dupuytren's disease]
 Musculoskeletal 1 0.905 – 1.11 0.983 419 4138 all phecode
729 Other disorders of soft tissues Musculoskeletal 1.03 0.997 – 1.07 0.0739 3642 27471 all phecode
729.1 Rheumatism, unspecified and fibrositis Musculoskeletal 1.14 0.894 – 1.46 0.287 74 726 all phecode
729.3 Panniculitis Musculoskeletal 0.844 0.699 – 1.02 0.0799 119 1174 all phecode
729.7 Nontraumatic compartment syndrome Musculoskeletal 1.05 0.83 – 1.34 0.662 67 664 all phecode
731
Osteitis deformans and osteopathies associated
Osteitis deformans and osteopathies associated with other disorders classified elsewhere
 Musculoskeletal 0.922 0.802 – 1.06 0.257 210 2091 all phecode
732 Osteochondropathies Musculoskeletal 0.926 0.831 – 1.03 0.159 361 3604 all phecode
732.1 Juvenile osteochondrosis Musculoskeletal 0.913 0.79 – 1.06 0.219 198 1969 all phecode
732.7 Osteochondritis dissecans Musculoskeletal 1.04 0.835 – 1.3 0.724 90 882 all phecode
733 Other disorders of bone and cartilage Musculoskeletal 0.98 0.949 – 1.01 0.232 4543 26941 all phecode
733.2 Cyst of bone Musculoskeletal 0.997 0.859 – 1.16 0.963 190 1900 all phecode
733.4 Aseptic necrosis of bone Musculoskeletal 1.02 0.928 – 1.12 0.717 518 5160 all phecode
733.6 Costochondritis Musculoskeletal 1.04 0.927 – 1.16 0.531 357 3562 all phecode
733.8 Malunion and nonunion of fracture Musculoskeletal 1.02 0.948 – 1.1 0.592 822 8205 all phecode
733.9 Chondromalacia Musculoskeletal 0.979 0.795 – 1.21 0.841 96 960 all phecode
735 Acquired foot deformities Musculoskeletal 0.999 0.964 – 1.04 0.968 3417 29622 all phecode
735.1 Flat foot Musculoskeletal 1.01 0.929 – 1.1 0.801 620 6092 all phecode
735.2 Acquired toe deformities Musculoskeletal 1.04 0.983 – 1.11 0.162 1323 11983 all phecode
735.21 Hammer toe (acquired) Musculoskeletal 1.04 0.971 – 1.12 0.245 825 7494 all phecode
735.23 Hallux rigidus Musculoskeletal 1.05 0.947 – 1.16 0.357 405 4005 all phecode
735.3 Hallux valgus (Bunion) Musculoskeletal 0.974 0.922 – 1.03 0.341 1470 14295 all phecode
736 Other acquired deformities of limbs Musculoskeletal 0.996 0.957 – 1.04 0.844 2763 26555 all phecode
736.1 Acquired deformities of forearm Musculoskeletal 1 0.824 – 1.22 0.971 104 1033 all phecode
736.2 Acquired deformities of finger Musculoskeletal 1.03 0.895 – 1.18 0.716 215 2142 all phecode
736.3 Acquired deformities of hip Musculoskeletal 1.14 0.885 – 1.47 0.313 60 590 all phecode
736.4 Genu valgum or varum (acquired) Musculoskeletal 0.915 0.819 – 1.02 0.119 325 3247 all phecode
736.5 Acquired deformities of knee Musculoskeletal 0.893 0.782 – 1.02 0.0942 246 2460 all phecode
736.6 Unequal leg length (acquired) Musculoskeletal 0.938 0.838 – 1.05 0.268 339 3365 all phecode
737 Curvature of spine Musculoskeletal 0.977 0.927 – 1.03 0.375 1566 15543 all phecode
737.1 Kyphosis (acquired) Musculoskeletal 1.05 0.959 – 1.16 0.278 479 4748 all phecode
737.2 Lordosis (acquired) Musculoskeletal 0.991 0.778 – 1.26 0.94 70 700 all phecode
737.3 Kyphoscoliosis and scoliosis Musculoskeletal 0.956 0.9 – 1.01 0.14 1203 11982 all phecode
738 Other acquired musculoskeletal deformity Musculoskeletal 0.993 0.951 – 1.04 0.727 2443 24187 all phecode
738.4 Acquired spondylolisthesis Musculoskeletal 1.01 0.951 – 1.08 0.681 1057 10542 all phecode
739 Contracture of joint Musculoskeletal 0.992 0.913 – 1.08 0.842 621 6207 all phecode
740 Osteoarthrosis Musculoskeletal 1.06 1.04 – 1.08 4.7e-08 16169 30268 all phecode
740.1 Osteoarthritis; localized Musculoskeletal 1.04 1.01 – 1.07 0.00563 7005 27422 all phecode
740.11 Osteoarthrosis, localized, primary Musculoskeletal 1.03 0.998 – 1.06 0.064 6176 26155 all phecode
740.12 Osteoarthrosis, localized, secondary Musculoskeletal 1.07 0.987 – 1.16 0.1 713 7116 all phecode
740.2 Osteoarthrosis, generalized Musculoskeletal 0.996 0.944 – 1.05 0.87 1609 12092 all phecode
740.3
Osteoarthrosis involving more than one site
Osteoarthrosis involving more than one site, but not specified as generalized
 Musculoskeletal 0.964 0.866 – 1.07 0.506 373 3586 all phecode
740.9 Osteoarthrosis NOS Musculoskeletal 1.06 1.04 – 1.08 5.89e-08 15497 30141 all phecode
741 Symptoms and disorders of the joints Musculoskeletal 1.01 0.99 – 1.04 0.271 8555 35884 all phecode
741.1 Ankylosis of joint Musculoskeletal 1.04 0.913 – 1.19 0.542 245 2445 all phecode
741.2 Stiffness of joint Musculoskeletal 1.02 0.96 – 1.08 0.557 1268 12594 all phecode
741.3 Difficulty in walking Musculoskeletal 1.02 0.978 – 1.06 0.356 2558 23116 all phecode
741.4 Joint effusions Musculoskeletal 0.998 0.957 – 1.04 0.927 2493 24199 all phecode
741.5 Hemarthrosis Musculoskeletal 1.01 0.821 – 1.23 0.95 94 937 all phecode
741.6 Villonodular synovitis Musculoskeletal 1.14 0.889 – 1.46 0.304 68 666 all phecode
742 Derangement of joint, non-traumatic Musculoskeletal 1.03 0.997 – 1.06 0.0748 4404 33771 all phecode
742.1 Loose body in joint Musculoskeletal 0.981 0.833 – 1.15 0.816 156 1554 all phecode
742.2
Pathological, developmental or recurrent
Pathological, developmental or recurrent dislocation
 Musculoskeletal 0.961 0.848 – 1.09 0.536 280 2792 all phecode
742.8 Articular cartilage disorder Musculoskeletal 0.989 0.865 – 1.13 0.868 245 2450 all phecode
742.9 Other derangement of joint Musculoskeletal 1.03 0.997 – 1.07 0.0704 4107 32972 all phecode
743
Osteoporosis, osteopenia and pathological
Osteoporosis, osteopenia and pathological fracture
 Musculoskeletal 1 0.979 – 1.03 0.801 9223 36921 all phecode
743.1 Osteoporosis Musculoskeletal 1.02 0.986 – 1.06 0.224 3712 19477 all phecode
743.11 Osteoporosis NOS Musculoskeletal 1.02 0.984 – 1.06 0.266 3657 19276 all phecode
743.12 Senile osteoporosis Musculoskeletal 0.983 0.907 – 1.07 0.685 703 5804 all phecode
743.13 Other specified osteoporosis Musculoskeletal 1.03 0.92 – 1.16 0.57 321 3141 all phecode
743.2 Pathologic fracture Musculoskeletal 0.997 0.936 – 1.06 0.937 1112 10563 all phecode
743.21 Pathologic fracture of vertebrae Musculoskeletal 1.01 0.923 – 1.12 0.76 475 4629 all phecode
743.22 Pathologic fracture of femur Musculoskeletal 1.03 0.865 – 1.23 0.733 143 1391 all phecode
743.4 Stress fracture Musculoskeletal 0.97 0.874 – 1.08 0.572 407 4046 all phecode
743.9
Osteopenia or other disorder of bone and
Osteopenia or other disorder of bone and cartilage
 Musculoskeletal 0.984 0.958 – 1.01 0.232 6970 35237 all phecode
745 Pain in joint Musculoskeletal 1 0.981 – 1.02 0.997 19848 26918 all phecode
747 Cardiac and circulatory congenital anomalies Congenital Anomalies 0.986 0.943 – 1.03 0.52 2236 22256 all phecode
747.1 Cardiac congenital anomalies Congenital Anomalies 1.01 0.958 – 1.06 0.78 1767 17598 all phecode
747.11 Cardiac shunt/ heart septal defect Congenital Anomalies 0.968 0.893 – 1.05 0.425 650 6497 all phecode
747.12 Valvular heart disease/ heart chambers Congenital Anomalies 0.979 0.908 – 1.06 0.583 751 7480 all phecode
747.13 Congenital anomalies of great vessels Congenital Anomalies 1.04 0.942 – 1.16 0.416 410 4090 all phecode
747.2
Congenital anomalies of peripheral vascular
Congenital anomalies of peripheral vascular system
 Congenital Anomalies 0.911 0.83 – 0.999 0.0486 501 5010 all phecode
748 Anomalies of respiratory system, congenital Congenital Anomalies 0.969 0.8 – 1.17 0.746 111 1110 all phecode
749 Congenital anomalies of face and neck Congenital Anomalies 1.09 1 – 1.2 0.0501 555 5549 all phecode
749.1 Cleft palate Congenital Anomalies 1.07 0.868 – 1.32 0.519 97 970 all phecode
749.2 Congenital anomalies of skull and face bones Congenital Anomalies 0.988 0.806 – 1.21 0.906 105 1041 all phecode
750 Digestive congenital anomalies Congenital Anomalies 0.896 0.835 – 0.961 0.0022 893 8919 all phecode
750.1 Upper gastrointestinal congenital anomalies Congenital Anomalies 0.831 0.745 – 0.927 0.000875 366 3655 all phecode
750.11 Esophageal atresia/tracheoesophageal fistula Congenital Anomalies 0.863 0.714 – 1.04 0.127 119 1185 all phecode
750.13 Congenital anomalies of mouth/tongue Congenital Anomalies 0.774 0.632 – 0.947 0.013 99 982 all phecode
750.14 Congenital anomalies of esophagus Congenital Anomalies 0.877 0.736 – 1.05 0.143 134 1332 all phecode
750.15 Congenital anomalies of stomach Congenital Anomalies 0.888 0.681 – 1.16 0.382 60 593 all phecode
750.2 Lower gastrointestinal congenital anomalies Congenital Anomalies 0.953 0.87 – 1.04 0.299 531 5300 all phecode
750.21 Congenital anomalies of intestine Congenital Anomalies 0.876 0.779 – 0.985 0.0276 313 3129 all phecode
750.22
Congenital anomaly of gallbladder, bile ducts
Congenital anomaly of gallbladder, bile ducts, liver, pancreas
 Congenital Anomalies 1.1 0.955 – 1.26 0.189 222 2214 all phecode
751 Genitourinary congenital anomalies Congenital Anomalies 1.02 0.972 – 1.07 0.454 2008 19975 all phecode
751.1 Congenital anomalies of genital organs Congenital Anomalies 1.06 0.972 – 1.16 0.189 574 5740 all phecode
751.11 Congenital anomalies of female genital organs Congenital Anomalies 1.08 0.971 – 1.21 0.151 384 3840 all phecode
751.12 Congenital anomalies of male genital organs Congenital Anomalies 1.06 0.9 – 1.25 0.476 153 1527 all phecode
751.2 Congenital anomalies of urinary system Congenital Anomalies 1.01 0.956 – 1.07 0.697 1379 13704 all phecode
751.21 Cystic kidney disease Congenital Anomalies 0.954 0.893 – 1.02 0.17 976 9685 all phecode
751.22 Other specified congenital anomalies of kidney Congenital Anomalies 1.15 1.02 – 1.3 0.0229 294 2927 all phecode
751.3 Obstructive genitourinary defect Congenital Anomalies 1.11 0.954 – 1.29 0.175 182 1809 all phecode
752 Nervous system congenital anomalies Congenital Anomalies 0.995 0.936 – 1.06 0.885 1133 11313 all phecode
752.1 Neural tube defects Congenital Anomalies 1.01 0.946 – 1.08 0.715 923 9209 all phecode
752.11 Spina bifida Congenital Anomalies 0.962 0.821 – 1.13 0.632 176 1760 all phecode
752.2
Other specified congenital anomalies of nervous
Other specified congenital anomalies of nervous system
 Congenital Anomalies 0.911 0.792 – 1.05 0.191 232 2320 all phecode
753 Congenital anomalies of the eye Congenital Anomalies 0.936 0.812 – 1.08 0.365 207 2051 all phecode
753.1 Congenital cataract and lens anomalies Congenital Anomalies 0.913 0.698 – 1.19 0.509 58 580 all phecode
753.2 Congenital anomalies of posterior segment of eye Congenital Anomalies 0.781 0.593 – 1.03 0.0798 56 546 all phecode
754 Congenital musculoskeletal deformities of spine Congenital Anomalies 1.02 0.964 – 1.08 0.463 1216 12116 all phecode
754.1 Lumbosacral spondylolysis, congenital Congenital Anomalies 1.12 0.948 – 1.33 0.181 135 1333 all phecode
754.2 Spondylolisthesis, congenital Congenital Anomalies 1.01 0.924 – 1.1 0.844 558 5570 all phecode
755 Congenital anomalies of limbs Congenital Anomalies 1.04 0.961 – 1.12 0.34 747 7458 all phecode
755.1 Congenital deformities of feet Congenital Anomalies 1.04 0.932 – 1.16 0.475 368 3663 all phecode
755.4
Congenital anomalies of upper limb, including
Congenital anomalies of upper limb, including shoulder girdle
 Congenital Anomalies 1.09 0.862 – 1.38 0.476 74 740 all phecode
755.6
Other congenital anomalies of lower limb
Other congenital anomalies of lower limb, including pelvic girdle
 Congenital Anomalies 1.07 0.955 – 1.2 0.236 321 3205 all phecode
755.61 Congenital hip dysplasia and deformity Congenital Anomalies 1.09 0.938 – 1.27 0.258 185 1847 all phecode
756 Other congenital musculoskeletal anomalies Congenital Anomalies 0.984 0.93 – 1.04 0.586 1358 13579 all phecode
756.1 Congenital anomalies of abdominal wall; diaphram Congenital Anomalies 0.805 0.614 – 1.05 0.115 68 680 all phecode
756.2
Pectus and other congenital anomalies of
Pectus and other congenital anomalies of ribs/sternum
 Congenital Anomalies 1.03 0.816 – 1.31 0.782 71 694 all phecode
756.3
Congenital anomalies of muscle, tendon, fascia
Congenital anomalies of muscle, tendon, fascia, and connective tissue
 Congenital Anomalies 0.915 0.818 – 1.02 0.125 335 3346 all phecode
756.5 Congenital osteodystrophies Congenital Anomalies 0.966 0.905 – 1.03 0.294 1003 10014 all phecode
757 Congenital anomalies of the integument Congenital Anomalies 1.05 0.944 – 1.16 0.374 401 4001 all phecode
758 Chromosomal anomalies and genetic disorders Congenital Anomalies 0.861 0.739 – 1 0.0537 185 1845 all phecode
758.1 Chromosomal anomalies Congenital Anomalies 0.874 0.732 – 1.04 0.138 135 1349 all phecode
759 Other and unspecified congenital anomalies Congenital Anomalies 0.933 0.854 – 1.02 0.124 557 5566 all phecode
759.1 Anomalies of endocrine glands, congenital Congenital Anomalies 0.931 0.728 – 1.19 0.567 71 710 all phecode
760 Back pain Symptoms 1.06 1.04 – 1.08 6.97e-10 16037 30719 all phecode
761 Cervicalgia Symptoms 1.05 1.02 – 1.07 0.000854 6528 39755 all phecode
763
Thoracic or lumbosacral neuritis or
Thoracic or lumbosacral neuritis or radiculitis, unspecified
 Symptoms 1.04 1.01 – 1.08 0.0249 3657 32599 all phecode
764 Sciatica Symptoms 1.07 1.03 – 1.1 0.000412 3542 32015 all phecode
765 Cervical radiculitis Symptoms 1.07 1.02 – 1.13 0.0059 1799 17851 all phecode
766 Neuralgia, neuritis, and radiculitis NOS Symptoms 1.07 1.04 – 1.1 1.62e-05 5124 37132 all phecode
767 Cervicocranial/Cervicobrachial syndrome Symptoms 0.969 0.798 – 1.18 0.747 117 1168 all phecode
769 Nonallopathic lesions NEC Symptoms 1.05 0.989 – 1.12 0.107 1131 11220 all phecode
770 Myalgia and myositis unspecified Symptoms 1.05 1.02 – 1.08 0.000533 5533 34303 all phecode
771 Musculoskeletal symptoms referable to limbs Symptoms 1.01 0.982 – 1.04 0.429 4799 35575 all phecode
771.1 Swelling of limb Symptoms 1.02 0.99 – 1.05 0.196 5743 35539 all phecode
771.2 Cramp of limb Symptoms 1.04 0.98 – 1.11 0.18 1079 10568 all phecode
772 Symptoms of the muscles Symptoms 0.99 0.946 – 1.04 0.681 2042 20221 all phecode
772.1 Muscular wasting and disuse atrophy Symptoms 1.04 0.936 – 1.15 0.498 422 4199 all phecode
772.2 Spasm of muscle Symptoms 1.02 0.973 – 1.06 0.476 2299 22726 all phecode
772.3 Muscle weakness Symptoms 1.02 0.985 – 1.06 0.225 2949 28064 all phecode
772.4 Rhabdomyolysis Symptoms 1.08 0.921 – 1.26 0.345 159 1572 all phecode
772.6 Facial weakness Symptoms 0.92 0.836 – 1.01 0.0877 478 4742 all phecode
780 Hypothermia/Chills Symptoms 1.01 0.917 – 1.11 0.839 453 4514 all phecode
781
Symptoms involving nervous and musculoskeletal
Symptoms involving nervous and musculoskeletal systems
 Symptoms 1.01 0.971 – 1.05 0.613 2822 26225 all phecode
781.1 Loss of height Symptoms 1.03 0.86 – 1.23 0.763 130 1269 all phecode
781.2 Abnormal posture Symptoms 0.83 0.632 – 1.09 0.179 57 567 all phecode
782.3 Edema Symptoms 1.03 1 – 1.06 0.0448 5874 36788 all phecode
782.6 Pallor and flushing Symptoms 1.08 1.01 – 1.15 0.0313 927 9252 all phecode
783 Fever of unknown origin Symptoms 1.03 1 – 1.06 0.0493 5733 40720 all phecode
783.1 Postprocedural fever Symptoms 1.01 0.893 – 1.13 0.933 300 2992 all phecode
785 Abdominal pain Symptoms 1.04 1.02 – 1.06 7.35e-05 16458 30297 all phecode
788 Syncope and collapse Symptoms 1.01 0.972 – 1.04 0.768 3851 35832 all phecode
789 Nausea and vomiting Symptoms 1.04 1.02 – 1.06 0.000873 10568 36098 all phecode
789.1 Persistent vomiting Symptoms 1.12 1.04 – 1.21 0.00258 798 7924 all phecode
790 Nonspecific findings on examination of blood Symptoms 1.02 0.973 – 1.06 0.48 2363 22690 all phecode
790.1 Elevated sedimentation rate Symptoms 1.07 0.941 – 1.22 0.295 236 2322 all phecode
790.6 Other abnormal blood chemistry Symptoms 1.02 0.991 – 1.04 0.196 7539 37788 all phecode
790.8 Elevated C-reactive protein (CRP) Symptoms 1.08 0.964 – 1.22 0.179 309 3075 all phecode
790.9 Abnormal arterial blood gases Symptoms 1.05 0.891 – 1.24 0.562 155 1521 all phecode
791 Gangrene Symptoms 1.17 1.04 – 1.31 0.00934 313 3115 all phecode
792
Abnormal Papanicolaou smear of cervix and
Abnormal Papanicolaou smear of cervix and cervical HPV
 Genitourinary 0.981 0.942 – 1.02 0.367 2820 14872 all phecode
792.1
Papanicolaou smear of cervix or vagina with
Papanicolaou smear of cervix or vagina with atypical squamous cells
 Genitourinary 1.01 0.95 – 1.08 0.719 1100 9861 all phecode
794
Abnormal results of other function studies
Abnormal results of other function studies (bladder, pancreas, placenta, spleen, etc)
 Symptoms 0.962 0.877 – 1.05 0.405 515 5133 all phecode
795
Other and nonspecific abnormal cytological
Other and nonspecific abnormal cytological, histological and immunological findings
 Symptoms 0.954 0.912 – 0.997 0.0376 2182 20242 all phecode
795.8 Abnormal tumor markers Symptoms 0.951 0.904 – 1 0.049 1745 15551 all phecode
795.81 Elevated carcinoembryonic antigen [CEA] Symptoms 1.15 0.881 – 1.51 0.301 61 605 all phecode
795.82 Elevated cancer antigen 125 [CA 125] Symptoms 0.88 0.759 – 1.02 0.0867 201 2000 all phecode
796 Elevated prostate specific antigen [PSA] Genitourinary 0.961 0.916 – 1.01 0.106 2125 9930 all phecode
797 Shock Symptoms 1 0.919 – 1.09 0.977 605 6050 all phecode
797.1 Cardiogenic shock Symptoms 0.996 0.872 – 1.14 0.956 242 2420 all phecode
798 Malaise and fatigue Symptoms 1.02 0.998 – 1.04 0.0773 11539 35196 all phecode
798.1 Chronic fatigue syndrome Symptoms 1.05 1 – 1.11 0.0341 1823 17795 all phecode
800 Fracture of lower limb Injuries & Poisonings 0.983 0.942 – 1.03 0.448 2344 22951 all phecode
800.1 Fracture of neck of femur Injuries & Poisonings 0.966 0.881 – 1.06 0.457 512 4961 all phecode
800.2 Fracture of unspecified part of femur Injuries & Poisonings 1 0.923 – 1.08 0.992 670 6582 all phecode
800.3 Fracture of tibia and fibula Injuries & Poisonings 0.932 0.869 – 1 0.0496 898 8966 all phecode
800.4 Fracture of patella Injuries & Poisonings 0.996 0.89 – 1.11 0.937 346 3456 all phecode
801 Fracture of ankle and foot Injuries & Poisonings 0.982 0.941 – 1.03 0.415 2358 22645 all phecode
801.1 Fracture of foot Injuries & Poisonings 0.969 0.911 – 1.03 0.325 1120 11178 all phecode
802 Fracture of pelvis Injuries & Poisonings 1.04 0.934 – 1.15 0.483 380 3765 all phecode
803 Fracture of upper limb Injuries & Poisonings 0.966 0.922 – 1.01 0.139 2051 20360 all phecode
803.1 Fracture of humerus Injuries & Poisonings 0.952 0.882 – 1.03 0.211 734 7322 all phecode
803.2 Fracture of radius and ulna Injuries & Poisonings 0.945 0.888 – 1.01 0.0744 1112 11075 all phecode
803.21 Colles' fracture Injuries & Poisonings 0.963 0.854 – 1.09 0.538 291 2904 all phecode
803.3 Fracture of clavicle or scapula Injuries & Poisonings 0.922 0.842 – 1.01 0.0789 514 5140 all phecode
804 Fracture of hand or wrist Injuries & Poisonings 0.989 0.94 – 1.04 0.68 1628 16042 all phecode
805
Fracture of vertebral column without mention of
Fracture of vertebral column without mention of spinal cord injury
 Injuries & Poisonings 1.01 0.954 – 1.07 0.719 1336 13242 all phecode
807 Fracture of ribs Injuries & Poisonings 0.967 0.893 – 1.05 0.407 683 6815 all phecode
809 Fracture of unspecified bones Injuries & Poisonings 0.992 0.954 – 1.03 0.671 2941 28633 all phecode
816 Cerebral laceration and contusion Injuries & Poisonings 0.918 0.699 – 1.21 0.538 54 531 all phecode
817 Concussion Injuries & Poisonings 1.06 0.99 – 1.13 0.097 1018 10149 all phecode
818 Intracranial hemorrhage (injury) Injuries & Poisonings 1.05 0.939 – 1.18 0.374 311 3104 all phecode
818.1 Subdural hemorrhage (injury) Injuries & Poisonings 0.977 0.786 – 1.22 0.837 90 895 all phecode
818.2 Subarachnoid hemorrhage (injury) Injuries & Poisonings 0.991 0.809 – 1.21 0.931 97 970 all phecode
819
Skull and face fracture and other intercranial
Skull and face fracture and other intercranial injury
 Injuries & Poisonings 1.01 0.971 – 1.06 0.537 2287 22671 all phecode
830 Dislocation Injuries & Poisonings 0.972 0.94 – 1.01 0.0998 3862 34720 all phecode
835 Internal derangement of knee Injuries & Poisonings 0.981 0.939 – 1.03 0.401 2231 21628 all phecode
836 Traumatic arthropathy Injuries & Poisonings 0.962 0.875 – 1.06 0.421 496 4954 all phecode
840 Sprains and strains Injuries & Poisonings 0.994 0.969 – 1.02 0.612 7838 37998 all phecode
840.1 Muscle/tendon sprain Injuries & Poisonings 1.03 0.946 – 1.13 0.456 537 5356 all phecode
840.2 Rotator cuff (capsule) sprain Injuries & Poisonings 1.06 1.01 – 1.11 0.031 1640 16263 all phecode
840.3 Joint/ligament sprain Injuries & Poisonings 0.993 0.955 – 1.03 0.74 2875 24879 all phecode
841 Sprains and strains of back and neck Injuries & Poisonings 0.966 0.916 – 1.02 0.191 1583 15592 all phecode
842 Other sprains and strains Injuries & Poisonings 0.981 0.928 – 1.04 0.499 1407 13924 all phecode
850 Hemorrhage or hematoma complicating a procedure Injuries & Poisonings 1.05 1 – 1.1 0.0401 2072 20649 all phecode
851
Complications of transplants and reattached
Complications of transplants and reattached limbs
 Injuries & Poisonings 1.07 1.03 – 1.12 0.000216 2982 27545 all phecode
853 Complication of colostomy or enterostomy Injuries & Poisonings 1.09 0.987 – 1.2 0.0912 460 4600 all phecode
854
Complications of cardiac/vascular device
Complications of cardiac/vascular device, implant, and graft
 Injuries & Poisonings 1.06 1.01 – 1.11 0.0142 1985 19675 all phecode
855
Complication of nervous system device, implant
Complication of nervous system device, implant, and graft
 Injuries & Poisonings 1.04 0.913 – 1.18 0.585 264 2640 all phecode
856
Vascular complications of surgery and medical
Vascular complications of surgery and medical procedures
 Injuries & Poisonings 1.01 0.895 – 1.14 0.857 293 2929 all phecode
857
Mechanical complication of unspecified
Mechanical complication of unspecified genitourinary device, implant, and graft
 Injuries & Poisonings 1.05 0.987 – 1.11 0.128 1310 13087 all phecode
858 Complication of internal orthopedic device Injuries & Poisonings 1.06 1.01 – 1.11 0.013 2213 21944 all phecode
859
Complication due to other implant and internal
Complication due to other implant and internal device
 Injuries & Poisonings 1.06 1.02 – 1.11 0.00705 2110 21070 all phecode
860 Bone marrow or stem cell transplant Neoplasms 0.891 0.76 – 1.05 0.157 166 1660 all phecode
870 Open wounds of head; neck; and trunk Injuries & Poisonings 1.01 0.979 – 1.04 0.501 4117 36734 all phecode
870.1 Open wound or laceration of eye or eyelid Injuries & Poisonings 0.98 0.849 – 1.13 0.786 204 2026 all phecode
870.2 Open wound of ear Injuries & Poisonings 0.854 0.721 – 1.01 0.0689 144 1437 all phecode
870.3 Other open wound of head and face Injuries & Poisonings 0.957 0.905 – 1.01 0.133 1346 13301 all phecode
870.4 Open wound of nose and sinus Injuries & Poisonings 0.98 0.848 – 1.13 0.783 207 2057 all phecode
870.5 Open wound of lip and mouth Injuries & Poisonings 0.995 0.876 – 1.13 0.936 275 2724 all phecode
870.6 Open wound of neck Injuries & Poisonings 1.02 0.879 – 1.18 0.806 214 2128 all phecode
870.8 Open wound of genital organs Injuries & Poisonings 1.05 0.888 – 1.25 0.547 144 1440 all phecode
871 Open wounds of extremities Injuries & Poisonings 1.02 0.981 – 1.05 0.376 3530 32903 all phecode
871.1 Open wound of hand except finger(s) Injuries & Poisonings 1.01 0.924 – 1.1 0.869 572 5701 all phecode
871.2 Open wound of finger(s) Injuries & Poisonings 1.01 0.949 – 1.08 0.678 984 9772 all phecode
871.3 Open wound of foot except toe(s) alone Injuries & Poisonings 1.04 0.949 – 1.14 0.394 490 4843 all phecode
871.4 Open wound of toe(s) Injuries & Poisonings 1 0.891 – 1.13 0.975 295 2921 all phecode
872 Traumatic amputation Injuries & Poisonings 1.07 0.983 – 1.17 0.115 551 5477 all phecode
874 Complication of amputation stump Injuries & Poisonings 1.16 0.991 – 1.36 0.0648 170 1697 all phecode
875 Non-healing surgical wound Injuries & Poisonings 1.06 0.975 – 1.16 0.166 572 5720 all phecode
876
Posttraumatic wound infection not elsewhere
Posttraumatic wound infection not elsewhere classified
 Injuries & Poisonings 1.19 1.11 – 1.28 3.07e-06 802 8003 all phecode
907 Injuries to the nervous system Injuries & Poisonings 1.03 0.965 – 1.1 0.382 1010 10096 all phecode
910 Superficial injury, infected Injuries & Poisonings 0.977 0.804 – 1.19 0.813 119 1161 all phecode
911 Blister Injuries & Poisonings 1.04 0.922 – 1.16 0.551 302 2996 all phecode
912 Insect bite Injuries & Poisonings 1.02 0.927 – 1.12 0.692 492 4886 all phecode
913 Toxic effect of venom Injuries & Poisonings 1.01 0.902 – 1.13 0.855 337 3326 all phecode
916 Contusion Injuries & Poisonings 1.01 0.979 – 1.04 0.516 4296 38033 all phecode
930 Allergic reaction to food Injuries & Poisonings 1.01 0.937 – 1.09 0.784 763 7596 all phecode
931
Contact dermatitis and other eczema due to
Contact dermatitis and other eczema due to plants [except food]
 Dermatologic 0.963 0.891 – 1.04 0.341 714 7072 all phecode
938 Dermatitis due to solar radiation Dermatologic 0.959 0.931 – 0.987 0.00497 5567 29098 all phecode
938.1 Acute dermatitis due to solar radiation Dermatologic 1.04 0.901 – 1.19 0.607 217 2164 all phecode
938.2 Chronic dermatitis due to solar radiation Dermatologic 0.955 0.927 – 0.984 0.00261 5307 28656 all phecode
939
Atopic/contact dermatitis due to other or
Atopic/contact dermatitis due to other or unspecified
 Dermatologic 0.974 0.948 – 1 0.0534 6704 32389 all phecode
939.1 Contact and allergic dermatitis of eyelid Dermatologic 1.07 0.859 – 1.32 0.559 91 870 all phecode
941 Adverse reaction to serum or vaccine Injuries & Poisonings 1.25 1.07 – 1.45 0.00392 188 1880 all phecode
942 Infusion and transfusion reaction Injuries & Poisonings 1.04 0.919 – 1.17 0.543 269 2688 all phecode
946 Anaphylactic shock NOS Injuries & Poisonings 0.965 0.878 – 1.06 0.462 500 4940 all phecode
947 Urticaria Dermatologic 1.02 0.961 – 1.09 0.499 1177 11454 all phecode
949 Allergies, other Injuries & Poisonings 1.01 0.982 – 1.04 0.53 7251 32350 all phecode
952
Spinal cord injury without evidence of spinal
Spinal cord injury without evidence of spinal bone injury
 Injuries & Poisonings 1.03 0.936 – 1.13 0.561 494 4940 all phecode
957 Injury to other and unspecified nerves Injuries & Poisonings 1.08 0.911 – 1.29 0.366 136 1352 all phecode
958
Certain early complications of trauma or
Certain early complications of trauma or procedure
 Injuries & Poisonings 1.11 1.04 – 1.17 0.000951 1217 12158 all phecode
958.1 Postoperative shock Injuries & Poisonings 1.12 0.952 – 1.31 0.174 169 1688 all phecode
958.2 Traumatic and surgical subcutaneous emphysema Injuries & Poisonings 1.13 0.928 – 1.38 0.224 114 1140 all phecode
960 Poisoning by antibiotics Injuries & Poisonings 1.03 0.989 – 1.08 0.144 2479 22087 all phecode
960.1
Adverse effects of antibacterials (not
Adverse effects of antibacterials (not penicillins)
 Injuries & Poisonings 1.09 0.974 – 1.22 0.134 342 3403 all phecode
960.2 Allergy/adverse effect of penicillin Injuries & Poisonings 1.02 0.966 – 1.07 0.523 1636 16005 all phecode
961 Poisoning by other anti-infectives Injuries & Poisonings 1.05 0.96 – 1.15 0.282 528 5234 all phecode
961.1 Poisoning/allergy of sulfonamides Injuries & Poisonings 1.13 1.06 – 1.2 0.000237 1065 10347 all phecode
962 Poisoning by hormones and synthetic substitutes Injuries & Poisonings 1.07 0.996 – 1.15 0.0655 803 7976 all phecode
962.1
Adrenal cortical steroids causing adverse
Adrenal cortical steroids causing adverse effects in therapeutic use
 Injuries & Poisonings 1.05 0.945 – 1.17 0.361 379 3782 all phecode
962.2
Insulins and antidiabetic agents causing
Insulins and antidiabetic agents causing adverse effects in therapeutic use
 Injuries & Poisonings 1.1 0.863 – 1.41 0.434 62 612 all phecode
962.3
Hormones and synthetic substitutes causing
Hormones and synthetic substitutes causing adverse effects in therapeutic use
 Injuries & Poisonings 1.09 0.992 – 1.2 0.072 478 4773 all phecode
963 Poisoning by primarily systemic agents Injuries & Poisonings 0.99 0.949 – 1.03 0.621 2533 24531 all phecode
963.1
Antineoplastic and immunosuppressive drugs
Antineoplastic and immunosuppressive drugs causing adverse effects
 Injuries & Poisonings 0.989 0.948 – 1.03 0.592 2469 24057 all phecode
964
Poisoning by agents primarily affecting blood
Poisoning by agents primarily affecting blood constituents
 Injuries & Poisonings 0.982 0.909 – 1.06 0.639 743 7337 all phecode
964.1 Anticoagulants causing adverse effects Injuries & Poisonings 1 0.928 – 1.09 0.925 712 7027 all phecode
965
Poisoning by analgesics, antipyretics, and
Poisoning by analgesics, antipyretics, and antirheumatics
 Injuries & Poisonings 1.09 1.02 – 1.17 0.0122 864 8601 all phecode
965.1
Opiates and related narcotics causing adverse
Opiates and related narcotics causing adverse effects in therapeutic use
 Injuries & Poisonings 1.08 1.02 – 1.14 0.00758 1469 14402 all phecode
965.3
Salicylates causing adverse effects in
Salicylates causing adverse effects in therapeutic use
 Injuries & Poisonings 0.898 0.743 – 1.08 0.262 119 1182 all phecode
966
Poisoning by anticonvulsants and
Poisoning by anticonvulsants and anti-Parkinsonism drugs
 Injuries & Poisonings 1.16 0.944 – 1.42 0.157 103 1006 all phecode
967
Adverse effects of sedatives or other central
Adverse effects of sedatives or other central nervous system depressants and anesthetics
 Injuries & Poisonings 1.05 0.991 – 1.11 0.0984 1254 12464 all phecode
969 Poisoning by psychotropic agents Injuries & Poisonings 1.06 0.938 – 1.2 0.34 281 2797 all phecode
971
Poisoning by drugs primarily affecting the
Poisoning by drugs primarily affecting the autonomic nervous system
 Injuries & Poisonings 0.824 0.64 – 1.06 0.134 67 643 all phecode
972
Poisoning by agents primarily affecting the
Poisoning by agents primarily affecting the cardiovascular system
 Injuries & Poisonings 0.926 0.821 – 1.04 0.209 288 2858 all phecode
972.1
Cardiac rhythm regulators causing adverse
Cardiac rhythm regulators causing adverse effects in therapeutic use
 Injuries & Poisonings 0.781 0.623 – 0.979 0.0321 80 776 all phecode
972.6 Antihypertensive agents causing adverse effects Injuries & Poisonings 0.936 0.772 – 1.14 0.503 104 1034 all phecode
974
Poisoning by water, mineral, and uric acid
Poisoning by water, mineral, and uric acid metabolism drugs
 Injuries & Poisonings 1.01 0.834 – 1.21 0.951 113 1130 all phecode
975
Poisoning by agents primarily acting on the
Poisoning by agents primarily acting on the smooth and skeletal muscles and respiratory system
 Injuries & Poisonings 1.17 0.929 – 1.48 0.181 81 810 all phecode
976
Poisoning by agents primarily affecting skin &
Poisoning by agents primarily affecting skin & mucous membrane, ophthalmological, otorhinolaryngological, & dental drugs
 Injuries & Poisonings 0.946 0.743 – 1.2 0.653 71 703 all phecode
977 Personal history of allergy to medicinal agents Injuries & Poisonings 1.08 1.02 – 1.13 0.00349 1763 16599 all phecode
979 Adverse drug events and drug allergies Injuries & Poisonings 1.02 0.987 – 1.06 0.222 3448 30885 all phecode
980
Encounter for long-term (current) use of
Encounter for long-term (current) use of antibiotics
 Infectious Diseases 0.971 0.919 – 1.03 0.297 1391 13877 all phecode
985 Toxic effect of other metals Injuries & Poisonings 1 0.764 – 1.32 0.974 57 564 all phecode
989
Toxic effect of other substances, chiefly
Toxic effect of other substances, chiefly nonmedicinal as to source
 Injuries & Poisonings 1 0.837 – 1.2 0.979 129 1275 all phecode
990 Effects radiation NOS Injuries & Poisonings 1 0.967 – 1.03 0.998 3927 31223 all phecode
994 Sepsis and SIRS Injuries & Poisonings 1.03 0.99 – 1.08 0.13 2192 21710 all phecode
994.1 Systemic inflammatory response syndrome (SIRS) Injuries & Poisonings 0.986 0.871 – 1.12 0.825 291 2910 all phecode
994.2 Sepsis Injuries & Poisonings 1.04 0.994 – 1.09 0.087 2086 20666 all phecode
994.21 Septic shock Injuries & Poisonings 0.977 0.899 – 1.06 0.591 627 6260 all phecode
008 Intestinal infection Infectious Diseases 0.99 0.936 – 1.05 0.735 1323 20134 exclusion phecode
008.5 Bacterial enteritis Infectious Diseases 0.984 0.903 – 1.07 0.72 561 8894 exclusion phecode
008.52 Intestinal infection due to C. difficile Infectious Diseases 0.994 0.903 – 1.1 0.908 451 7060 exclusion phecode
008.6 Viral Enteritis Infectious Diseases 1.02 0.913 – 1.15 0.676 301 5242 exclusion phecode
010 Tuberculosis Infectious Diseases 0.925 0.762 – 1.12 0.431 124 1680 exclusion phecode
031 Diseases due to other mycobacteria Infectious Diseases 0.855 0.618 – 1.18 0.345 33 578 exclusion phecode
038 Septicemia Infectious Diseases 1.07 1 – 1.13 0.0393 1167 16821 exclusion phecode
038.1 Gram negative septicemia Infectious Diseases 1.03 0.901 – 1.17 0.687 248 3793 exclusion phecode
038.2 Gram positive septicemia Infectious Diseases 1.17 0.961 – 1.42 0.12 105 1600 exclusion phecode
038.3 Bacteremia Infectious Diseases 1.05 0.964 – 1.15 0.242 520 8118 exclusion phecode
041 Bacterial infection NOS Infectious Diseases 1.06 1.02 – 1.11 0.00148 2956 27240 exclusion phecode
041.1 Staphylococcus infections Infectious Diseases 1.1 1.03 – 1.18 0.00819 821 11692 exclusion phecode
041.11 Methicillin sensitive Staphylococcus aureus Infectious Diseases 1.11 0.998 – 1.22 0.0547 402 6263 exclusion phecode
041.12 Methicillin resistant Staphylococcus aureus Infectious Diseases 1.06 0.957 – 1.18 0.26 371 5403 exclusion phecode
041.2 Streptococcus infection Infectious Diseases 1.05 0.977 – 1.13 0.19 824 11096 exclusion phecode
041.21 Rheumatic fever / chorea Infectious Diseases 1.08 0.907 – 1.28 0.405 141 1714 exclusion phecode
041.4 E. coli Infectious Diseases 1.09 0.994 – 1.19 0.0681 557 7980 exclusion phecode
041.8 H. pylori Infectious Diseases 0.931 0.778 – 1.11 0.438 129 1745 exclusion phecode
041.9 Infection with drug-resistant microorganisms Infectious Diseases 1.02 0.874 – 1.2 0.774 167 2674 exclusion phecode
053 Herpes zoster Infectious Diseases 1.04 0.966 – 1.13 0.286 706 10715 exclusion phecode
053.1 Herpes zoster with nervous system complications Infectious Diseases 1.03 0.835 – 1.27 0.772 90 1509 exclusion phecode
054 Herpes simplex Infectious Diseases 0.935 0.87 – 1 0.0675 821 11419 exclusion phecode
070 Viral hepatitis Infectious Diseases 1.04 0.945 – 1.15 0.408 461 5738 exclusion phecode
070.1 Viral hepatitis A Infectious Diseases 0.861 0.643 – 1.15 0.315 45 595 exclusion phecode
070.2 Viral hepatitis B Infectious Diseases 0.977 0.808 – 1.18 0.808 115 1479 exclusion phecode
070.3 Viral hepatitis C Infectious Diseases 1.1 0.977 – 1.24 0.113 304 3657 exclusion phecode
070.4 Chronic hepatitis Infectious Diseases 0.899 0.73 – 1.11 0.318 98 1333 exclusion phecode
070.9 Hepatitis NOS Infectious Diseases 1.03 0.946 – 1.12 0.501 601 7868 exclusion phecode
071 Human immunodeficiency virus [HIV] disease Infectious Diseases 0.798 0.618 – 1.03 0.0839 64 986 exclusion phecode
071.1 HIV infection, symptomatic Infectious Diseases 0.72 0.536 – 0.968 0.0297 48 792 exclusion phecode
078 Viral warts & HPV Infectious Diseases 0.948 0.902 – 0.997 0.0375 1684 21751 exclusion phecode
079 Viral infection Infectious Diseases 0.969 0.933 – 1.01 0.0981 3202 25705 exclusion phecode
079.1 Varicella infection Infectious Diseases 0.946 0.902 – 0.993 0.0234 1873 22609 exclusion phecode
079.2 Infectious mononucleosis Infectious Diseases 0.933 0.793 – 1.1 0.401 158 2153 exclusion phecode
079.9 Viremia, NOS Infectious Diseases 1.03 0.924 – 1.14 0.619 376 6036 exclusion phecode
080 Postoperative infection Infectious Diseases 1.07 1.01 – 1.13 0.0182 1426 17558 exclusion phecode
081
Infection/inflammation of internal prosthetic
Infection/inflammation of internal prosthetic device; implant; and graft
 Infectious Diseases 1.14 1.06 – 1.22 0.000572 792 10718 exclusion phecode
090
Sexually transmitted infections (not HIV or
Sexually transmitted infections (not HIV or hepatitis)
 Infectious Diseases 0.907 0.827 – 0.994 0.036 508 6662 exclusion phecode
110 Dermatophytosis / Dermatomycosis Infectious Diseases 0.933 0.884 – 0.985 0.0124 1452 21042 exclusion phecode
110.1 Dermatophytosis Infectious Diseases 0.93 0.879 – 0.985 0.0135 1296 18977 exclusion phecode
110.11 Dermatophytosis of nail Infectious Diseases 0.957 0.889 – 1.03 0.237 785 11411 exclusion phecode
110.12 Althete's foot Infectious Diseases 0.966 0.865 – 1.08 0.53 341 5410 exclusion phecode
110.13 Dermatophytosis of the body Infectious Diseases 0.888 0.793 – 0.995 0.0403 313 5432 exclusion phecode
110.2 Dermatomycoses Infectious Diseases 0.87 0.751 – 1.01 0.0648 194 2815 exclusion phecode
112 Candidiasis Infectious Diseases 0.994 0.946 – 1.04 0.819 1729 21852 exclusion phecode
112.3 Candidiasis of skin and nails Infectious Diseases 1.04 0.915 – 1.18 0.552 248 4710 exclusion phecode
117 Mycoses Infectious Diseases 0.936 0.826 – 1.06 0.294 267 4323 exclusion phecode
117.1 Histoplasmosis Infectious Diseases 1.06 0.773 – 1.45 0.72 41 539 exclusion phecode
117.4 Aspergillosis Infectious Diseases 0.922 0.703 – 1.21 0.558 56 1005 exclusion phecode
130 Spirochetal infection Infectious Diseases 0.893 0.718 – 1.11 0.308 78 1157 exclusion phecode
130.1 Lyme disease Infectious Diseases 0.871 0.671 – 1.13 0.302 56 804 exclusion phecode
131 Protozoan infection Infectious Diseases 1.11 0.771 – 1.6 0.571 27 447 exclusion phecode
132 Infestation (lice, mites) Infectious Diseases 0.848 0.681 – 1.06 0.139 84 1348 exclusion phecode
134 Helminthiases Infectious Diseases 0.798 0.574 – 1.11 0.178 38 535 exclusion phecode
134.1 Intestinal helminthiases Infectious Diseases 0.848 0.539 – 1.33 0.473 19 330 exclusion phecode
136 Other infectious and parasitic diseases Infectious Diseases 1.02 0.973 – 1.08 0.372 1693 22166 exclusion phecode
145 Cancer of mouth Neoplasms 0.99 0.929 – 1.06 0.764 1084 9441 exclusion phecode
145.1 Cancer of lip Neoplasms 0.852 0.635 – 1.14 0.284 56 483 exclusion phecode
145.2 Cancer of tongue Neoplasms 0.985 0.893 – 1.09 0.756 473 4129 exclusion phecode
145.3 Cancer of major salivary glands Neoplasms 0.984 0.868 – 1.12 0.798 277 2386 exclusion phecode
145.4 Cancer of the gums Neoplasms 0.954 0.789 – 1.15 0.627 121 1079 exclusion phecode
145.5 Cancer of the mouth floor Neoplasms 1.16 0.987 – 1.37 0.0717 160 1323 exclusion phecode
149 Cancer of larynx, pharynx, nasal cavities Neoplasms 0.95 0.888 – 1.02 0.143 931 8211 exclusion phecode
149.1 Cancer of oropharynx Neoplasms 1.06 0.926 – 1.21 0.407 248 2185 exclusion phecode
149.2 Cancer of nasopharynx Neoplasms 0.848 0.648 – 1.11 0.229 58 638 exclusion phecode
149.3 Cancer of hypopharynx Neoplasms 0.879 0.667 – 1.16 0.361 60 503 exclusion phecode
149.4 Cancer of larynx Neoplasms 0.949 0.841 – 1.07 0.403 294 2467 exclusion phecode
149.5
Hx of malignant neoplasm of oral cavity and
Hx of malignant neoplasm of oral cavity and pharynx
 Neoplasms 0.952 0.856 – 1.06 0.359 379 3539 exclusion phecode
149.9 Cancer of of nasal cavities Neoplasms 0.897 0.762 – 1.06 0.194 163 1528 exclusion phecode
150 Cancer of esophagus Neoplasms 0.928 0.817 – 1.05 0.248 271 2894 exclusion phecode
151 Cancer of stomach Neoplasms 1.11 0.991 – 1.25 0.0696 330 3310 exclusion phecode
153 Colorectal cancer Neoplasms 1.01 0.942 – 1.08 0.797 894 10083 exclusion phecode
153.2 Colon cancer Neoplasms 0.996 0.922 – 1.08 0.916 710 8069 exclusion phecode
153.3
Malignant neoplasm of rectum, rectosigmoid
Malignant neoplasm of rectum, rectosigmoid junction, and anus
 Neoplasms 0.991 0.904 – 1.09 0.841 511 5704 exclusion phecode
155 Cancer of liver and intrahepatic bile duct Neoplasms 1.06 0.943 – 1.19 0.331 322 3430 exclusion phecode
155.1 Malignant neoplasm of liver, primary Neoplasms 1.1 0.95 – 1.26 0.209 214 2300 exclusion phecode
157 Pancreatic cancer Neoplasms 1.07 0.952 – 1.2 0.259 334 3326 exclusion phecode
158
Neoplasm of unspecified nature of digestive
Neoplasm of unspecified nature of digestive system
 Neoplasms 1.09 1.02 – 1.17 0.0144 902 10619 exclusion phecode
159
Malignant neoplasm of other and ill-defined
Malignant neoplasm of other and ill-defined sites within the digestive organs and peritoneum
 Neoplasms 1.02 0.956 – 1.08 0.593 1125 12098 exclusion phecode
159.2
Malignant neoplasm of small intestine
Malignant neoplasm of small intestine, including duodenum
 Neoplasms 1.05 0.883 – 1.26 0.562 136 1439 exclusion phecode
159.3
Malignant neoplasm of gallbladder and
Malignant neoplasm of gallbladder and extrahepatic bile ducts
 Neoplasms 1 0.823 – 1.22 0.985 110 1027 exclusion phecode
159.4
Malignant neoplasm of retroperitoneum and
Malignant neoplasm of retroperitoneum and peritoneum
 Neoplasms 0.869 0.749 – 1.01 0.0649 189 2019 exclusion phecode
164 Cancer of intrathoracic organs Neoplasms 1.1 0.883 – 1.38 0.391 85 861 exclusion phecode
165 Cancer within the respiratory system Neoplasms 1.04 0.964 – 1.11 0.338 860 8575 exclusion phecode
165.1 Cancer of bronchus; lung Neoplasms 1.04 0.954 – 1.12 0.404 655 6765 exclusion phecode
170 Cancer of bone and connective tissue Neoplasms 0.99 0.934 – 1.05 0.743 1253 11699 exclusion phecode
170.1 Bone cancer Neoplasms 0.977 0.892 – 1.07 0.62 536 5053 exclusion phecode
170.2 Cancer of connective tissue Neoplasms 0.982 0.916 – 1.05 0.618 886 8252 exclusion phecode
172 Skin cancer Neoplasms 0.963 0.934 – 0.993 0.0174 5639 22175 exclusion phecode
172.1 Melanomas of skin, dx or hx Neoplasms 0.94 0.906 – 0.976 0.00123 3453 19848 exclusion phecode
172.11 Melanomas of skin Neoplasms 0.931 0.89 – 0.973 0.00167 2253 16460 exclusion phecode
172.2 Other non-epithelial cancer of skin Neoplasms 0.972 0.939 – 1.01 0.101 4509 20017 exclusion phecode
172.21 Basal cell carcinoma Neoplasms 0.944 0.901 – 0.988 0.0133 2197 15387 exclusion phecode
172.22 Squamous cell carcinoma Neoplasms 0.97 0.918 – 1.03 0.281 1501 11286 exclusion phecode
172.3 Carcinoma in situ of skin Neoplasms 0.978 0.91 – 1.05 0.548 869 7858 exclusion phecode
173 Neoplasm of uncertain behavior of skin Neoplasms 0.981 0.919 – 1.05 0.57 1014 12290 exclusion phecode
174 Breast cancer Neoplasms 0.969 0.924 – 1.02 0.204 2071 10900 exclusion phecode
174.1 Breast cancer [female] Neoplasms 0.974 0.927 – 1.02 0.292 1984 10409 exclusion phecode
174.11 Malignant neoplasm of female breast Neoplasms 0.981 0.933 – 1.03 0.441 1952 10361 exclusion phecode
174.3 Neoplasm of uncertain behavior of breast Neoplasms 0.984 0.819 – 1.18 0.86 134 1625 exclusion phecode
175 Acquired absence of breast Neoplasms 0.962 0.883 – 1.05 0.381 576 6534 exclusion phecode
180 Cervical cancer and dysplasia Neoplasms 1.01 0.944 – 1.08 0.748 905 8977 exclusion phecode
180.1 Cervical cancer Neoplasms 1.02 0.914 – 1.15 0.676 340 3596 exclusion phecode
180.3
Cervical intraepithelial neoplasia [CIN]
Cervical intraepithelial neoplasia [CIN] [Cervical dysplasia]
 Neoplasms 1 0.924 – 1.09 0.952 641 7007 exclusion phecode
182 Malignant neoplasm of uterus Neoplasms 1.04 0.944 – 1.14 0.452 496 5208 exclusion phecode
184 Cancer of other female genital organs Neoplasms 0.914 0.847 – 0.986 0.0208 751 7884 exclusion phecode
184.1
Malignant neoplasm of ovary and other uterine
Malignant neoplasm of ovary and other uterine adnexa
 Neoplasms 0.891 0.802 – 0.991 0.0337 385 3839 exclusion phecode
184.11 Malignant neoplasm of ovary Neoplasms 0.883 0.782 – 0.998 0.0471 292 2888 exclusion phecode
184.2
Cancer of other female genital organs
Cancer of other female genital organs (excluding uterus and ovary)
 Neoplasms 0.965 0.866 – 1.08 0.527 362 4068 exclusion phecode
185 Cancer of prostate Neoplasms 0.997 0.945 – 1.05 0.905 1925 6736 exclusion phecode
187 Cancer of other male genital organs Neoplasms 1.07 0.93 – 1.24 0.332 219 2212 exclusion phecode
187.1
Malignant neoplasm of unspecified male genital
Malignant neoplasm of unspecified male genital organ
 Neoplasms 1.03 0.811 – 1.32 0.786 80 710 exclusion phecode
187.2 Malignant neoplasm of testis Neoplasms 1 0.83 – 1.21 0.985 119 1243 exclusion phecode
187.8
Neoplasm of uncertain behavior of male genital
Neoplasm of uncertain behavior of male genital organs
 Neoplasms 1.31 0.88 – 1.95 0.184 29 352 exclusion phecode
189
Cancer of urinary organs (incl. kidney and
Cancer of urinary organs (incl. kidney and bladder)
 Neoplasms 1.05 1 – 1.1 0.044 1965 15022 exclusion phecode
189.1 Cancer of kidney and renal pelvis Neoplasms 1.06 0.991 – 1.13 0.0885 965 9210 exclusion phecode
189.11 Malignant neoplasm of kidney, except pelvis Neoplasms 1.05 0.975 – 1.12 0.208 846 8060 exclusion phecode
189.12 Malignant neoplasm of renal pelvis Neoplasms 0.984 0.831 – 1.17 0.851 148 1501 exclusion phecode
189.2 Cancer of bladder Neoplasms 1.03 0.965 – 1.09 0.407 1203 9657 exclusion phecode
189.21 Malignant neoplasm of bladder Neoplasms 1.02 0.959 – 1.09 0.508 1134 8977 exclusion phecode
189.4 Malignant neoplasm of other urinary organs Neoplasms 0.999 0.906 – 1.1 0.985 459 4193 exclusion phecode
190 Cancer of eye Neoplasms 1.2 0.946 – 1.52 0.134 81 911 exclusion phecode
191
Manlignant and unknown neoplasms of brain and
Manlignant and unknown neoplasms of brain and nervous system
 Neoplasms 1.02 0.937 – 1.1 0.708 662 7278 exclusion phecode
191.1 Cancer of brain and nervous system Neoplasms 1.03 0.932 – 1.14 0.558 425 4791 exclusion phecode
191.11 Cancer of brain Neoplasms 1.06 0.947 – 1.18 0.318 354 4123 exclusion phecode
193 Thyroid cancer Neoplasms 1.01 0.933 – 1.1 0.766 633 6370 exclusion phecode
194 Cancer of other endocrine glands Neoplasms 1.08 0.968 – 1.21 0.163 353 3804 exclusion phecode
195 Cancer, suspected or other Neoplasms 1.01 0.981 – 1.03 0.618 11042 18386 exclusion phecode
195.1 Malignant neoplasm, other Neoplasms 1.01 0.98 – 1.03 0.674 10829 18375 exclusion phecode
195.3 Malignant neoplasm of head, face, and neck Neoplasms 0.952 0.882 – 1.03 0.204 784 6277 exclusion phecode
196 Radiotherapy Neoplasms 0.923 0.873 – 0.975 0.00444 1500 11121 exclusion phecode
197 Chemotherapy Neoplasms 0.98 0.942 – 1.02 0.332 3075 16292 exclusion phecode
198 Secondary malignant neoplasm Neoplasms 0.99 0.955 – 1.03 0.59 4014 16097 exclusion phecode
198.1 Secondary malignancy of lymph nodes Neoplasms 0.981 0.94 – 1.02 0.383 2623 14563 exclusion phecode
198.2 Secondary malignancy of respiratory organs Neoplasms 0.955 0.882 – 1.04 0.265 672 6754 exclusion phecode
198.3
Secondary malignant neoplasm of digestive
Secondary malignant neoplasm of digestive systems
 Neoplasms 0.942 0.863 – 1.03 0.183 569 5613 exclusion phecode
198.4 Secondary malignant neoplasm of liver Neoplasms 0.957 0.87 – 1.05 0.372 490 4917 exclusion phecode
198.5 Secondary malignancy of brain/spine Neoplasms 0.995 0.898 – 1.1 0.924 415 4157 exclusion phecode
198.6 Secondary malignancy of bone Neoplasms 0.955 0.872 – 1.05 0.319 526 5422 exclusion phecode
198.7 Secondary malignant neoplasm of skin Neoplasms 0.958 0.827 – 1.11 0.562 217 2137 exclusion phecode
199 Neoplasm of uncertain behavior Neoplasms 1.01 0.975 – 1.05 0.525 3392 17866 exclusion phecode
199.4 Neurofibromatosis Neoplasms 1.03 0.784 – 1.35 0.829 59 637 exclusion phecode
200 Myeloproliferative disease Neoplasms 0.94 0.859 – 1.03 0.174 523 7336 exclusion phecode
200.1 Polycythemia vera Neoplasms 0.816 0.655 – 1.02 0.0695 87 1467 exclusion phecode
201 Hodgkin's disease Neoplasms 1.08 0.889 – 1.32 0.429 108 1146 exclusion phecode
202 Cancer of other lymphoid, histiocytic tissue Neoplasms 0.947 0.886 – 1.01 0.107 965 10205 exclusion phecode
202.2 Non-Hodgkins lymphoma Neoplasms 0.903 0.841 – 0.971 0.00564 818 8740 exclusion phecode
202.21 Nodular lymphoma Neoplasms 0.816 0.739 – 0.901 5.43e-05 431 4537 exclusion phecode
202.22 Reticulosarcoma Neoplasms 0.991 0.802 – 1.22 0.934 95 1144 exclusion phecode
202.24 Large cell lymphoma Neoplasms 0.953 0.765 – 1.19 0.67 90 1056 exclusion phecode
204 Leukemia Neoplasms 0.959 0.862 – 1.07 0.449 373 4509 exclusion phecode
204.1 Lymphoid leukemia Neoplasms 0.986 0.83 – 1.17 0.873 143 1565 exclusion phecode
204.11 Lymphoid leukemia, acute Neoplasms 0.682 0.489 – 0.951 0.0241 37 523 exclusion phecode
204.12 Lymphoid leukemia, chronic Neoplasms 1.08 0.892 – 1.3 0.443 113 1103 exclusion phecode
204.2 Myeloid leukemia Neoplasms 0.837 0.694 – 1.01 0.0651 120 1708 exclusion phecode
204.21 Myeloid leukemia, acute Neoplasms 0.85 0.662 – 1.09 0.204 70 994 exclusion phecode
204.22 Myeloid leukemia, chronic Neoplasms 0.814 0.559 – 1.19 0.286 28 405 exclusion phecode
204.4 Multiple myeloma Neoplasms 0.935 0.772 – 1.13 0.493 113 1367 exclusion phecode
208 Benign neoplasm of colon Neoplasms 0.997 0.967 – 1.03 0.857 4999 25423 exclusion phecode
209 Neuroendocrine tumors Neoplasms 1.12 0.952 – 1.31 0.178 166 1665 exclusion phecode
210 Benign neoplasm of lip, oral cavity, and pharynx Neoplasms 0.974 0.919 – 1.03 0.387 1241 12599 exclusion phecode
211
Benign neoplasm of other parts of digestive
Benign neoplasm of other parts of digestive system
 Neoplasms 1.04 1.01 – 1.08 0.0244 3527 26185 exclusion phecode
212
Benign neoplasm of respiratory and
Benign neoplasm of respiratory and intrathoracic organs
 Neoplasms 1.03 0.967 – 1.09 0.375 1156 12257 exclusion phecode
213 Benign neoplasm of bone and articular cartilage Neoplasms 0.969 0.909 – 1.03 0.329 1050 11466 exclusion phecode
214 Lipoma Neoplasms 1.04 0.965 – 1.12 0.301 748 9352 exclusion phecode
214.1 Lipoma of skin and subcutaneous tissue Neoplasms 1.08 0.979 – 1.18 0.126 474 5752 exclusion phecode
215
Other benign neoplasm of connective and other
Other benign neoplasm of connective and other soft tissue
 Neoplasms 1.02 0.984 – 1.07 0.24 2781 26895 exclusion phecode
216 Benign neoplasm of skin Neoplasms 0.941 0.915 – 0.967 1.64e-05 6580 24853 exclusion phecode
216.1 Screening for malignant neoplasms of the skin Neoplasms 0.852 0.687 – 1.06 0.145 89 1170 exclusion phecode
217 Vascular hamartomas and non-neoplastic nevi Neoplasms 0.894 0.837 – 0.956 0.00106 954 11743 exclusion phecode
217.1 Nevus, non-neoplastic Neoplasms 0.888 0.828 – 0.951 0.000742 880 10986 exclusion phecode
218 Benign neoplasm of uterus Neoplasms 0.989 0.947 – 1.03 0.618 2536 12109 exclusion phecode
218.1 Uterine leiomyoma Neoplasms 0.984 0.923 – 1.05 0.617 1072 11336 exclusion phecode
218.2 Other benign neoplasm of uterus Neoplasms 0.985 0.939 – 1.03 0.545 1993 11948 exclusion phecode
220 Benign neoplasm of ovary Neoplasms 0.963 0.884 – 1.05 0.387 581 6397 exclusion phecode
221 Benign neoplasm of other female genital organs Neoplasms 0.99 0.935 – 1.05 0.735 1355 10443 exclusion phecode
222 Benign neoplasm of male genital organs Neoplasms 1 0.927 – 1.08 0.957 704 6703 exclusion phecode
223
Benign neoplasm of kidney and other urinary
Benign neoplasm of kidney and other urinary organs
 Neoplasms 1.03 0.97 – 1.1 0.324 1236 9042 exclusion phecode
224 Benign neoplasm of eye Neoplasms 0.88 0.788 – 0.982 0.0228 341 4389 exclusion phecode
224.1 Benign neoplasm of eye, uveal Neoplasms 0.881 0.78 – 0.996 0.0422 280 3707 exclusion phecode
225
Benign neoplasm of brain and other parts of
Benign neoplasm of brain and other parts of nervous system
 Neoplasms 1 0.93 – 1.08 0.909 724 8148 exclusion phecode
225.1
Benign neoplasm of brain, cranial nerves
Benign neoplasm of brain, cranial nerves, meninges
 Neoplasms 1.01 0.927 – 1.1 0.823 584 6334 exclusion phecode
225.2 Benign neoplasm of spinal cord, meninges Neoplasms 1.02 0.865 – 1.19 0.846 159 2002 exclusion phecode
226 Benign neoplasm of thyroid glands Neoplasms 0.973 0.905 – 1.05 0.46 814 8843 exclusion phecode
227
Benign neoplasm of other endocrine glands and
Benign neoplasm of other endocrine glands and related structures
 Neoplasms 0.949 0.89 – 1.01 0.109 1060 11306 exclusion phecode
227.1 Benign neoplasm of adrenal gland Neoplasms 1.01 0.888 – 1.16 0.834 242 3033 exclusion phecode
227.2 Benign neoplasm of parathyroid gland Neoplasms 0.886 0.809 – 0.97 0.00908 531 5350 exclusion phecode
227.3
Benign neoplasm of pituitary gland and
Benign neoplasm of pituitary gland and craniopharyngeal duct (pouch)
 Neoplasms 1.03 0.906 – 1.16 0.689 281 2878 exclusion phecode
228 Hemangioma and lymphangioma, any site Neoplasms 0.937 0.881 – 0.996 0.0363 1135 13638 exclusion phecode
228.1 Hemangioma of skin and subcutaneous tissue Neoplasms 0.929 0.859 – 1.01 0.0687 695 8592 exclusion phecode
229 Benign neoplasm of unspecified sites Neoplasms 0.98 0.951 – 1.01 0.186 5341 24567 exclusion phecode
229.1 Benign neoplasm of lymph nodes Neoplasms 0.983 0.95 – 1.02 0.327 4094 22828 exclusion phecode
240 Simple and unspecified goiter Endocrine/metabolic 0.962 0.883 – 1.05 0.371 595 6931 exclusion phecode
241 Nontoxic nodular goiter Endocrine/metabolic 0.99 0.941 – 1.04 0.711 1692 15611 exclusion phecode
241.1 Nontoxic uninodular goiter Endocrine/metabolic 1.01 0.95 – 1.07 0.808 1280 13898 exclusion phecode
241.2 Nontoxic multinodular goiter Endocrine/metabolic 1.03 0.954 – 1.11 0.461 739 8682 exclusion phecode
242 Thyrotoxicosis with or without goiter Endocrine/metabolic 1.05 0.971 – 1.13 0.231 748 9269 exclusion phecode
242.1 Graves' disease Endocrine/metabolic 0.988 0.876 – 1.12 0.85 306 3544 exclusion phecode
242.2 Toxic multinodular goiter Endocrine/metabolic 1.11 0.855 – 1.44 0.437 61 839 exclusion phecode
242.3 Exophthalmos Endocrine/metabolic 1 0.862 – 1.17 0.952 180 2034 exclusion phecode
242.31 Thyrotoxic exophthalmos Endocrine/metabolic 1.03 0.832 – 1.26 0.814 97 1037 exclusion phecode
244 Hypothyroidism Endocrine/metabolic 1 0.97 – 1.04 0.91 4683 22694 exclusion phecode
244.1 Secondary hypothyroidism Endocrine/metabolic 1.01 0.95 – 1.08 0.727 1087 12044 exclusion phecode
244.2 Acquired hypothyroidism Endocrine/metabolic 1.01 0.934 – 1.1 0.753 660 8318 exclusion phecode
244.4 Hypothyroidism NOS Endocrine/metabolic 0.996 0.963 – 1.03 0.834 4294 22330 exclusion phecode
245 Thyroiditis Endocrine/metabolic 0.955 0.869 – 1.05 0.348 481 5569 exclusion phecode
245.2 Chronic thyroiditis Endocrine/metabolic 0.963 0.867 – 1.07 0.475 406 4636 exclusion phecode
245.21 Chronic lymphocytic thyroiditis Endocrine/metabolic 0.951 0.856 – 1.06 0.355 402 4589 exclusion phecode
246 Other disorders of thyroid Endocrine/metabolic 1.05 1.01 – 1.09 0.0151 3558 20993 exclusion phecode
246.2 Thyroid cyst Endocrine/metabolic 1.1 0.835 – 1.45 0.497 56 685 exclusion phecode
246.7 Abnormal results of function study of thyroid Endocrine/metabolic 1 0.905 – 1.11 0.992 427 5949 exclusion phecode
249 Secondary diabetes mellitus Endocrine/metabolic 1.09 0.977 – 1.21 0.124 449 6091 exclusion phecode
250 Diabetes mellitus Endocrine/metabolic 1.06 1.02 – 1.09 0.000382 6846 23921 exclusion phecode
250.1 Type 1 diabetes Endocrine/metabolic 1.06 0.969 – 1.16 0.203 1180 8631 exclusion phecode
250.11 Type 1 diabetes with ketoacidosis Endocrine/metabolic 1.25 0.983 – 1.59 0.0687 161 701 exclusion phecode
250.12 Type 1 diabetes with renal manifestations Endocrine/metabolic 1.09 0.921 – 1.3 0.311 268 1965 exclusion phecode
250.13 Type 1 diabetes with ophthalmic manifestations Endocrine/metabolic 0.983 0.84 – 1.15 0.836 417 2218 exclusion phecode
250.14 Type 1 diabetes with neurological manifestations Endocrine/metabolic 1.08 0.915 – 1.29 0.349 297 1953 exclusion phecode
250.15
Diabetes type 1 with peripheral circulatory
Diabetes type 1 with peripheral circulatory disorders
 Endocrine/metabolic 1.06 0.78 – 1.45 0.697 57 598 exclusion phecode
250.2 Type 2 diabetes Endocrine/metabolic 1.08 1.05 – 1.12 4.8e-06 4852 22097 exclusion phecode
250.21 Type 2 diabetes with ketoacidosis Endocrine/metabolic 1.15 0.912 – 1.44 0.243 136 964 exclusion phecode
250.22 Type 2 diabetes with renal manifestations Endocrine/metabolic 1.09 0.997 – 1.19 0.0581 673 9775 exclusion phecode
250.23 Type 2 diabetes with ophthalmic manifestations Endocrine/metabolic 1.04 0.94 – 1.15 0.453 687 7009 exclusion phecode
250.24 Type 2 diabetes with neurological manifestations Endocrine/metabolic 1.16 1.07 – 1.26 0.00039 876 11960 exclusion phecode
250.25
Diabetes type 2 with peripheral circulatory
Diabetes type 2 with peripheral circulatory disorders
 Endocrine/metabolic 1.08 0.933 – 1.24 0.317 241 4465 exclusion phecode
250.3 Insulin pump user Endocrine/metabolic 1.05 0.98 – 1.12 0.175 1582 15216 exclusion phecode
250.4 Abnormal glucose Endocrine/metabolic 1.02 0.976 – 1.06 0.441 3714 22915 exclusion phecode
250.41 Impaired fasting glucose Endocrine/metabolic 1 0.923 – 1.08 0.993 726 11589 exclusion phecode
250.42 Other abnormal glucose Endocrine/metabolic 1.02 0.977 – 1.06 0.397 3349 22424 exclusion phecode
250.5 Glycosuria or Acetonuria Endocrine/metabolic 1.21 0.923 – 1.59 0.168 56 804 exclusion phecode
250.6 Polyneuropathy in diabetes Endocrine/metabolic 1.16 1.06 – 1.27 0.0017 752 9699 exclusion phecode
250.7 Diabetic retinopathy Endocrine/metabolic 1.04 0.955 – 1.13 0.394 751 7107 exclusion phecode
251 Other disorders of pancreatic internal secretion Endocrine/metabolic 1.05 0.953 – 1.16 0.319 446 5773 exclusion phecode
251.1 Hypoglycemia Endocrine/metabolic 1.13 1.02 – 1.25 0.0198 553 6520 exclusion phecode
252 Disorders of parathyroid gland Endocrine/metabolic 0.99 0.934 – 1.05 0.737 1270 15250 exclusion phecode
252.1 Hyperparathyroidism Endocrine/metabolic 0.997 0.938 – 1.06 0.914 1154 13950 exclusion phecode
252.2 Hypoparathyroidism Endocrine/metabolic 0.966 0.856 – 1.09 0.578 303 3537 exclusion phecode
253
Disorders of the pituitary gland and its
Disorders of the pituitary gland and its hypothalamic control
 Endocrine/metabolic 1 0.908 – 1.11 0.923 428 5871 exclusion phecode
253.1 Pituitary hyperfunction Endocrine/metabolic 0.986 0.827 – 1.18 0.875 132 1859 exclusion phecode
253.11 Acromegaly and gigantism Endocrine/metabolic 0.971 0.72 – 1.31 0.849 46 586 exclusion phecode
253.2 Pituitary hypofunction Endocrine/metabolic 1.14 0.943 – 1.39 0.172 121 1544 exclusion phecode
253.3 Diabetes insipidus Endocrine/metabolic 1.12 0.839 – 1.48 0.449 49 601 exclusion phecode
253.4 Anterior pituitary disorders Endocrine/metabolic 1.1 0.807 – 1.51 0.539 43 779 exclusion phecode
253.7 Other disorders of neurohypophysis Endocrine/metabolic 1.07 0.8 – 1.44 0.641 47 713 exclusion phecode
255 Disorders of adrenal glands Endocrine/metabolic 1.03 0.959 – 1.12 0.384 737 10260 exclusion phecode
255.1 Adrenal hyperfunction Endocrine/metabolic 0.995 0.853 – 1.16 0.949 181 2624 exclusion phecode
255.11 Cushing's syndrome Endocrine/metabolic 0.963 0.781 – 1.19 0.728 93 1299 exclusion phecode
255.12 Hyperaldosteronism Endocrine/metabolic 0.984 0.747 – 1.3 0.908 57 923 exclusion phecode
255.2 Adrenal hypofunction Endocrine/metabolic 0.997 0.881 – 1.13 0.964 270 4262 exclusion phecode
255.21 Glucocorticoid deficiency Endocrine/metabolic 0.973 0.857 – 1.1 0.67 254 4082 exclusion phecode
256 Ovarian dysfunction Endocrine/metabolic 0.953 0.879 – 1.03 0.243 648 7944 exclusion phecode
256.4 Polycystic ovaries Endocrine/metabolic 1.06 0.959 – 1.18 0.248 405 5551 exclusion phecode
257 Testicular dysfunction Endocrine/metabolic 1.06 0.947 – 1.18 0.323 358 6115 exclusion phecode
257.1 Testicular hypofunction Endocrine/metabolic 1.05 0.938 – 1.17 0.4 340 5897 exclusion phecode
258 Iatrogenic endocrine disorders Endocrine/metabolic 1.54 1.15 – 2.07 0.00402 55 603 exclusion phecode
258.1 Postablative ovarian failure Endocrine/metabolic 0.816 0.622 – 1.07 0.142 53 808 exclusion phecode
259 Other endocrine disorders Endocrine/metabolic 0.986 0.898 – 1.08 0.769 489 7100 exclusion phecode
260 Protein-calorie malnutrition Endocrine/metabolic 1.06 1 – 1.11 0.0339 1565 19137 exclusion phecode
260.1 Cachexia Endocrine/metabolic 1.05 0.896 – 1.24 0.528 163 2057 exclusion phecode
260.2 severe protein-calorie malnutrition Endocrine/metabolic 1.03 0.967 – 1.11 0.321 922 11956 exclusion phecode
260.22 Nutritional marasmus Endocrine/metabolic 1.06 0.945 – 1.19 0.316 314 4399 exclusion phecode
260.3 Adult failure to thrive Endocrine/metabolic 1.13 1 – 1.26 0.0439 313 4410 exclusion phecode
260.6 Anorexia Endocrine/metabolic 1.08 0.979 – 1.2 0.12 398 6171 exclusion phecode
260.7 Polyphagia Endocrine/metabolic 1.28 0.863 – 1.89 0.222 23 467 exclusion phecode
261 Vitamin deficiency Endocrine/metabolic 0.972 0.937 – 1.01 0.121 3498 25812 exclusion phecode
261.1 Vitamin A deficiency Endocrine/metabolic 0.856 0.583 – 1.26 0.428 27 519 exclusion phecode
261.2 Vitamin B-complex deficiencies Endocrine/metabolic 0.958 0.859 – 1.07 0.447 348 6042 exclusion phecode
261.4 Vitamin D deficiency Endocrine/metabolic 0.978 0.942 – 1.02 0.244 3265 25841 exclusion phecode
261.41 Rickets or osteomalacia Endocrine/metabolic 0.889 0.583 – 1.35 0.582 21 369 exclusion phecode
262 Mineral deficiency NEC Endocrine/metabolic 1.01 0.921 – 1.11 0.786 458 8548 exclusion phecode
263 Other nutritional deficiency Endocrine/metabolic 0.989 0.918 – 1.07 0.775 746 11485 exclusion phecode
264 Lack of normal physiological development Endocrine/metabolic 0.967 0.812 – 1.15 0.712 131 1791 exclusion phecode
264.2 Failure to thrive (childhood) Endocrine/metabolic 1.02 0.771 – 1.35 0.895 52 902 exclusion phecode
264.9
Lack of normal physiological development
Lack of normal physiological development, unspecified
 Endocrine/metabolic 0.871 0.666 – 1.14 0.312 56 628 exclusion phecode
269 Proteinuria Endocrine/metabolic 0.985 0.911 – 1.06 0.7 702 9342 exclusion phecode
270
Disorders of protein plasma/amino-acid
Disorders of protein plasma/amino-acid transport and metabolism
 Endocrine/metabolic 0.924 0.837 – 1.02 0.118 428 6385 exclusion phecode
270.1 Disturbances of amino-acid transport Endocrine/metabolic 0.954 0.766 – 1.19 0.678 85 1187 exclusion phecode
270.11
Disturbances of sulphur-bearing amino-acid
Disturbances of sulphur-bearing amino-acid metabolism
 Endocrine/metabolic 0.908 0.705 – 1.17 0.456 68 948 exclusion phecode
270.2 Disorders of amino-acid metabolism Endocrine/metabolic 1.06 0.757 – 1.49 0.723 31 628 exclusion phecode
270.3 Disorders of plasma protein metabolism Endocrine/metabolic 0.924 0.825 – 1.03 0.169 322 4814 exclusion phecode
270.32 Paraproteinemia Endocrine/metabolic 0.912 0.779 – 1.07 0.25 165 2458 exclusion phecode
270.33 Amyloidosis Endocrine/metabolic 0.901 0.656 – 1.24 0.516 39 472 exclusion phecode
270.34 Alpha-1-antitrypsin deficiency Endocrine/metabolic 1.19 0.817 – 1.72 0.371 28 461 exclusion phecode
270.38
Other specified disorders of plasma protein
Other specified disorders of plasma protein metabolism
 Endocrine/metabolic 0.891 0.747 – 1.06 0.198 131 2005 exclusion phecode
271
Disorders of carbohydrate transport and
Disorders of carbohydrate transport and metabolism
 Endocrine/metabolic 0.985 0.929 – 1.04 0.621 1221 18790 exclusion phecode
271.3
Intestinal disaccharidase deficiencies and
Intestinal disaccharidase deficiencies and disaccharide malabsorption
 Endocrine/metabolic 0.983 0.926 – 1.04 0.573 1188 18272 exclusion phecode
271.9
Other disorders of carbohydrate transport and
Other disorders of carbohydrate transport and metabolism
 Endocrine/metabolic 0.898 0.657 – 1.23 0.498 41 678 exclusion phecode
272 Disorders of lipoid metabolism Endocrine/metabolic 1 0.974 – 1.03 0.981 10060 20488 exclusion phecode
272.1 Hyperlipidemia Endocrine/metabolic 1 0.975 – 1.03 0.943 10043 20476 exclusion phecode
272.11 Hypercholesterolemia Endocrine/metabolic 0.977 0.937 – 1.02 0.286 2930 16233 exclusion phecode
272.12 Hyperglyceridemia Endocrine/metabolic 0.933 0.849 – 1.02 0.146 476 8849 exclusion phecode
272.13 Mixed hyperlipidemia Endocrine/metabolic 0.987 0.932 – 1.05 0.666 1472 13790 exclusion phecode
272.9 Unspecified disorder of lipoid metabolism Endocrine/metabolic 1 0.841 – 1.19 0.998 138 2216 exclusion phecode
274 Gout and other crystal arthropathies Endocrine/metabolic 1.05 0.989 – 1.11 0.112 1222 14679 exclusion phecode
274.1 Gout Endocrine/metabolic 1.05 0.991 – 1.12 0.0979 1161 14190 exclusion phecode
274.11 Gouty arthropathy Endocrine/metabolic 1.06 0.966 – 1.17 0.212 458 6722 exclusion phecode
274.2 Crystal arthropathies Endocrine/metabolic 0.959 0.777 – 1.18 0.699 90 1251 exclusion phecode
274.21 Chondrocalcinosis Endocrine/metabolic 0.94 0.757 – 1.17 0.575 85 1170 exclusion phecode
275 Disorders of mineral metabolism Endocrine/metabolic 1.03 0.985 – 1.08 0.191 2196 25197 exclusion phecode
275.1 Disorders of iron metabolism Hematopoietic 1.11 0.904 – 1.37 0.312 82 1439 exclusion phecode
275.11 Hereditary hemochromatosis Hematopoietic 1.18 0.886 – 1.58 0.254 48 646 exclusion phecode
275.2 Disorders of copper metabolism Endocrine/metabolic 1.24 0.85 – 1.81 0.264 26 410 exclusion phecode
275.3 Disorders of magnesium metabolism Endocrine/metabolic 1.03 0.942 – 1.12 0.523 532 7661 exclusion phecode
275.5 Disorders of calcium/phosphorus metabolism Endocrine/metabolic 1.02 0.966 – 1.07 0.555 1728 21390 exclusion phecode
275.51 Hypocalcemia Endocrine/metabolic 0.996 0.907 – 1.09 0.939 490 6124 exclusion phecode
275.53 Disorders of phosphorus metabolism Endocrine/metabolic 1.07 0.985 – 1.16 0.109 664 9157 exclusion phecode
275.6 Hypercalcemia Endocrine/metabolic 0.986 0.912 – 1.07 0.732 701 9403 exclusion phecode
276
Disorders of fluid, electrolyte, and acid-base
Disorders of fluid, electrolyte, and acid-base balance
 Endocrine/metabolic 1.02 0.992 – 1.06 0.135 4568 26723 exclusion phecode
276.1 Electrolyte imbalance Endocrine/metabolic 1.02 0.98 – 1.06 0.345 2986 24426 exclusion phecode
276.11 Hyperosmolality and/or hypernatremia Endocrine/metabolic 0.942 0.815 – 1.09 0.418 202 3759 exclusion phecode
276.12 Hyposmolality and/or hyponatremia Endocrine/metabolic 1.03 0.966 – 1.09 0.415 1195 16110 exclusion phecode
276.13 Hyperpotassemia Endocrine/metabolic 1.04 0.987 – 1.11 0.134 1322 17484 exclusion phecode
276.14 Hypopotassemia Endocrine/metabolic 1.02 0.95 – 1.09 0.627 895 14759 exclusion phecode
276.4 Acid-base balance disorder Endocrine/metabolic 1.08 1 – 1.15 0.036 879 14174 exclusion phecode
276.41 Acidosis Endocrine/metabolic 1.07 0.99 – 1.15 0.088 753 12246 exclusion phecode
276.42 Alkalosis Endocrine/metabolic 1.04 0.896 – 1.2 0.631 189 3293 exclusion phecode
276.5 Hypovolemia Endocrine/metabolic 1.03 0.99 – 1.08 0.13 2213 24713 exclusion phecode
276.6 Fluid overload Endocrine/metabolic 1.07 0.981 – 1.18 0.122 495 9146 exclusion phecode
276.8 Polydipsia Endocrine/metabolic 1.26 0.945 – 1.67 0.116 48 875 exclusion phecode
277 Other disorders of metabolism Endocrine/metabolic 0.975 0.929 – 1.02 0.318 1781 24413 exclusion phecode
277.2
Other disorders of purine and pyrimidine
Other disorders of purine and pyrimidine metabolism
 Endocrine/metabolic 0.943 0.792 – 1.12 0.505 133 2623 exclusion phecode
277.4 Disorders of bilirubin excretion Endocrine/metabolic 1.03 0.926 – 1.15 0.591 374 4862 exclusion phecode
277.5 Other disorders of lipoid metabolism Endocrine/metabolic 0.969 0.876 – 1.07 0.54 397 6232 exclusion phecode
277.51 Lipoprotein disorders Endocrine/metabolic 0.984 0.879 – 1.1 0.777 319 5148 exclusion phecode
277.7 Dysmetabolic syndrome X Endocrine/metabolic 0.989 0.863 – 1.13 0.878 219 5627 exclusion phecode
278 Overweight, obesity and other hyperalimentation Endocrine/metabolic 1.05 1.03 – 1.08 1.62e-05 10021 21607 exclusion phecode
278.1 Obesity Endocrine/metabolic 1.06 1.04 – 1.09 1.44e-06 8626 21598 exclusion phecode
278.11 Morbid obesity Endocrine/metabolic 1.09 1.05 – 1.13 2.33e-06 3414 21481 exclusion phecode
278.3 Localized adiposity Endocrine/metabolic 1.16 0.966 – 1.39 0.112 128 2525 exclusion phecode
278.4 Abnormal weight gain Endocrine/metabolic 1.04 0.966 – 1.12 0.302 778 13854 exclusion phecode
279 Disorders involving the immune mechanism Endocrine/metabolic 1.01 0.96 – 1.07 0.636 1439 20077 exclusion phecode
279.1 Immunity deficiency Endocrine/metabolic 1.02 0.932 – 1.11 0.676 517 8009 exclusion phecode
279.11 Deficiency of humoral immunity Endocrine/metabolic 0.898 0.758 – 1.06 0.216 140 2255 exclusion phecode
279.2 Autoimmune disease NEC Endocrine/metabolic 1.09 0.971 – 1.21 0.15 330 5287 exclusion phecode
279.7 Other immunological findings Endocrine/metabolic 1.02 0.973 – 1.06 0.447 2203 25699 exclusion phecode
279.8
Other specified disorders involving the immune
Other specified disorders involving the immune mechanism
 Endocrine/metabolic 1.11 0.984 – 1.25 0.0903 274 4225 exclusion phecode
280 Iron deficiency anemias Hematopoietic 1.01 0.965 – 1.06 0.678 2055 22330 exclusion phecode
280.1
Iron deficiency anemias, unspecified or not due
Iron deficiency anemias, unspecified or not due to blood loss
 Hematopoietic 1.01 0.964 – 1.06 0.677 1981 22172 exclusion phecode
280.2
Iron deficiency anemia secondary to blood loss
Iron deficiency anemia secondary to blood loss (chronic)
 Hematopoietic 0.987 0.917 – 1.06 0.717 781 12406 exclusion phecode
281 Other deficiency anemia Hematopoietic 1.01 0.875 – 1.17 0.883 206 3622 exclusion phecode
281.1 Megaloblastic anemia Hematopoietic 1.05 0.863 – 1.28 0.619 111 1767 exclusion phecode
281.11 Pernicious anemia Hematopoietic 1.04 0.778 – 1.4 0.77 47 772 exclusion phecode
281.12 Other vitamin B12 deficiency anemia Hematopoietic 1.11 0.893 – 1.39 0.34 90 1275 exclusion phecode
281.9 Deficiency anemias Hematopoietic 0.974 0.793 – 1.2 0.805 103 2013 exclusion phecode
282 Hereditary hemolytic anemias Hematopoietic 1.15 0.974 – 1.35 0.1 153 2270 exclusion phecode
282.8 Other hemoglobinopathies Hematopoietic 1.18 0.956 – 1.45 0.124 100 1473 exclusion phecode
282.9 Other hereditary hemolytic anemias Hematopoietic 1.19 0.95 – 1.5 0.129 83 1376 exclusion phecode
283 Acquired hemolytic anemias Hematopoietic 0.99 0.795 – 1.23 0.926 86 1100 exclusion phecode
283.1 Autoimmune hemolytic anemias Hematopoietic 1.09 0.787 – 1.52 0.595 38 445 exclusion phecode
284 Aplastic anemia Hematopoietic 0.897 0.803 – 1 0.0567 337 4933 exclusion phecode
284.1 Pancytopenia Hematopoietic 0.901 0.801 – 1.01 0.0829 301 4325 exclusion phecode
285 Other anemias Hematopoietic 1.04 1.01 – 1.07 0.00405 6336 24493 exclusion phecode
285.1 Acute posthemorrhagic anemia Hematopoietic 1.03 0.984 – 1.08 0.194 1802 19804 exclusion phecode
285.2 Anemia of chronic disease Hematopoietic 1.02 0.954 – 1.09 0.564 943 14113 exclusion phecode
285.21 Anemia in chronic kidney disease Hematopoietic 1.01 0.912 – 1.13 0.804 380 6349 exclusion phecode
285.22 Anemia in neoplastic disease Hematopoietic 0.98 0.879 – 1.09 0.715 363 4907 exclusion phecode
286 Coagulation defects Hematopoietic 1.02 0.974 – 1.07 0.375 1820 23321 exclusion phecode
286.1 Congenital coagulation defects Hematopoietic 0.902 0.758 – 1.07 0.246 137 1741 exclusion phecode
286.11 Von willebrand's disease Hematopoietic 0.994 0.753 – 1.31 0.964 54 586 exclusion phecode
286.12
Congenital deficiency of other clotting factors
Congenital deficiency of other clotting factors (including factor VII)
 Hematopoietic 0.871 0.676 – 1.12 0.288 62 890 exclusion phecode
286.2
Encounter for long-term (current) use of
Encounter for long-term (current) use of anticoagulants
 Hematopoietic 0.998 0.946 – 1.05 0.951 1507 17805 exclusion phecode
286.3
Coagulation defects complicating pregnancy or
Coagulation defects complicating pregnancy or postpartum
 Hematopoietic 0.943 0.737 – 1.21 0.638 68 783 exclusion phecode
286.4 Acquired coagulation factor deficiency Hematopoietic 1.06 0.869 – 1.3 0.557 108 1727 exclusion phecode
286.5
Hemorrhagic disorder due to intrinsic
Hemorrhagic disorder due to intrinsic circulating anticoagulants
 Hematopoietic 1.05 0.788 – 1.41 0.727 51 867 exclusion phecode
286.6 Defibrination syndrome Hematopoietic 1.02 0.964 – 1.08 0.466 1253 17583 exclusion phecode
286.7 Other and unspecified coagulation defects Hematopoietic 1.02 0.965 – 1.08 0.504 1431 20377 exclusion phecode
286.8 Hypercoagulable state Hematopoietic 0.952 0.863 – 1.05 0.332 440 5920 exclusion phecode
286.81 Primary hypercoagulable state Hematopoietic 0.948 0.857 – 1.05 0.303 421 5671 exclusion phecode
286.9 Abnormal coagulation profile Hematopoietic 1.1 0.996 – 1.2 0.0594 469 7846 exclusion phecode
287 Purpura and other hemorrhagic conditions Hematopoietic 0.983 0.934 – 1.03 0.507 1622 19750 exclusion phecode
287.1 Spontaneous ecchymoses Hematopoietic 0.802 0.644 – 0.999 0.0491 87 1440 exclusion phecode
287.3 Thrombocytopenia Hematopoietic 0.986 0.934 – 1.04 0.618 1450 18240 exclusion phecode
287.31 Primary thrombocytopenia Hematopoietic 0.975 0.865 – 1.1 0.673 303 4165 exclusion phecode
287.32 Secondary thrombocytopenia Hematopoietic 0.95 0.84 – 1.08 0.418 283 3960 exclusion phecode
287.4 Qualitative platelet defects Hematopoietic 0.868 0.665 – 1.13 0.297 57 803 exclusion phecode
288 Diseases of white blood cells Hematopoietic 1.03 0.985 – 1.07 0.199 2376 25939 exclusion phecode
288.1 Decreased white blood cell count Hematopoietic 0.988 0.919 – 1.06 0.738 836 11131 exclusion phecode
288.11 Neutropenia Hematopoietic 0.972 0.891 – 1.06 0.518 582 7642 exclusion phecode
288.2 Elevated white blood cell count Hematopoietic 1.04 0.993 – 1.09 0.0979 1909 24732 exclusion phecode
288.3 Eosinophilia Hematopoietic 0.998 0.806 – 1.24 0.988 88 1302 exclusion phecode
289 Other diseases of blood and blood-forming organs Hematopoietic 1.01 0.937 – 1.08 0.857 827 12164 exclusion phecode
289.3
Personal history of diseases of blood and
Personal history of diseases of blood and blood-forming organs
 Hematopoietic 0.954 0.864 – 1.05 0.353 433 6356 exclusion phecode
289.4 Lymphadenitis Hematopoietic 0.954 0.913 – 0.997 0.0374 2205 24599 exclusion phecode
289.5 Diseases of spleen Hematopoietic 0.868 0.746 – 1.01 0.068 187 2692 exclusion phecode
289.8 Polycythemia, secondary Hematopoietic 0.801 0.648 – 0.991 0.0411 91 1687 exclusion phecode
289.9 Abnormality of red blood cells Hematopoietic 1.11 0.949 – 1.3 0.194 173 2634 exclusion phecode
290
Delirium dementia and amnestic and other
Delirium dementia and amnestic and other cognitive disorders
 Mental Disorders 1.02 0.939 – 1.12 0.586 548 8000 exclusion phecode
290.1 Dementias Mental Disorders 0.827 0.717 – 0.954 0.00912 204 3437 exclusion phecode
290.11 Alzheimer's disease Mental Disorders 0.8 0.627 – 1.02 0.0732 65 991 exclusion phecode
290.12 Dementia with cerebral degenerations Mental Disorders 0.621 0.421 – 0.915 0.0162 24 574 exclusion phecode
290.13 Senile dementia Mental Disorders 0.858 0.721 – 1.02 0.087 140 2150 exclusion phecode
290.16 Vascular dementia Mental Disorders 0.922 0.639 – 1.33 0.665 30 547 exclusion phecode
290.2 Delirium due to conditions classified elsewhere Mental Disorders 1.14 1.01 – 1.28 0.0292 302 5063 exclusion phecode
290.3
Other persistent mental disorders due to
Other persistent mental disorders due to conditions classified elsewhere
 Mental Disorders 0.967 0.859 – 1.09 0.575 296 6023 exclusion phecode
291
Other specified nonpsychotic and/or transient
Other specified nonpsychotic and/or transient mental disorders
 Mental Disorders 0.995 0.924 – 1.07 0.885 751 17716 exclusion phecode
291.1
Transient mental disorders due to conditions
Transient mental disorders due to conditions classified elsewhere
 Mental Disorders 0.869 0.709 – 1.07 0.179 98 1357 exclusion phecode
291.4
Specific nonpsychotic mental disorders due to
Specific nonpsychotic mental disorders due to brain damage
 Mental Disorders 1.01 0.867 – 1.19 0.856 163 3444 exclusion phecode
291.8 Alteration of consciousness Mental Disorders 1.02 0.93 – 1.11 0.723 520 14118 exclusion phecode
292 Neurological disorders Mental Disorders 1.01 0.971 – 1.06 0.56 2410 27839 exclusion phecode
292.1 Aphasia/speech disturbance Mental Disorders 0.941 0.88 – 1.01 0.08 924 13996 exclusion phecode
292.11 Aphasia Mental Disorders 0.881 0.779 – 0.996 0.0429 277 4610 exclusion phecode
292.12 Symbolic dysfunction Mental Disorders 0.791 0.633 – 0.987 0.0382 85 1433 exclusion phecode
292.2 Mild cognitive impairment Mental Disorders 0.933 0.778 – 1.12 0.456 122 2650 exclusion phecode
292.3 Memory loss Mental Disorders 0.963 0.887 – 1.04 0.361 620 12764 exclusion phecode
292.4 Altered mental status Mental Disorders 1.08 1.01 – 1.15 0.0222 967 15911 exclusion phecode
292.5 Transient alteration of awareness Mental Disorders 0.918 0.774 – 1.09 0.326 135 3038 exclusion phecode
292.6 Hallucinations Mental Disorders 1.03 0.803 – 1.33 0.791 59 1513 exclusion phecode
293 Symptoms involving head and neck Mental Disorders 0.942 0.812 – 1.09 0.431 187 2820 exclusion phecode
293.1
Swelling, mass, or lump in head and neck
Swelling, mass, or lump in head and neck [Space-occupying lesion, intracranial NOS]
 Mental Disorders 0.975 0.935 – 1.02 0.223 2552 26272 exclusion phecode
295 Schizophrenia and other psychotic disorders Mental Disorders 1.16 1.04 – 1.31 0.0108 313 6599 exclusion phecode
295.1 Schizophrenia Mental Disorders 1.11 0.866 – 1.43 0.405 66 1087 exclusion phecode
295.2 Paranoid disorders Mental Disorders 1.46 1.04 – 2.05 0.0276 38 869 exclusion phecode
295.3 Psychosis Mental Disorders 1.15 1 – 1.31 0.0444 234 5339 exclusion phecode
296 Mood disorders Mental Disorders 1.08 1.05 – 1.11 2.29e-07 7567 17059 exclusion phecode
296.1 Bipolar Mental Disorders 1.07 0.984 – 1.17 0.109 565 9472 exclusion phecode
296.2 Depression Mental Disorders 1.08 1.05 – 1.11 4.01e-08 7238 17056 exclusion phecode
296.22 Major depressive disorder Mental Disorders 1.09 1.06 – 1.12 1.39e-08 6689 17055 exclusion phecode
297 Suicidal ideation or attempt Mental Disorders 1.02 0.916 – 1.14 0.717 371 7640 exclusion phecode
297.1 Suicidal ideation Mental Disorders 1.06 0.939 – 1.2 0.337 277 6175 exclusion phecode
297.2 Suicide or self-inflicted injury Mental Disorders 1.06 0.879 – 1.27 0.552 117 2288 exclusion phecode
300 Anxiety disorders Mental Disorders 1.07 1.04 – 1.1 7.33e-06 7903 17051 exclusion phecode
300.1 Anxiety disorder Mental Disorders 1.07 1.04 – 1.1 6.26e-06 7426 17054 exclusion phecode
300.11 Generalized anxiety disorder Mental Disorders 1.09 1.04 – 1.14 0.000283 2351 16745 exclusion phecode
300.12 Agorophobia, social phobia, and panic disorder Mental Disorders 1.1 1 – 1.21 0.0504 537 9603 exclusion phecode
300.13 Phobia Mental Disorders 1.09 0.983 – 1.2 0.102 444 7892 exclusion phecode
300.3 Obsessive-compulsive disorders Mental Disorders 1.13 0.951 – 1.34 0.166 146 2560 exclusion phecode
300.4 Dysthymic disorder Mental Disorders 1.06 0.986 – 1.13 0.118 871 13638 exclusion phecode
300.8 Acute reaction to stress Mental Disorders 1.14 0.974 – 1.33 0.102 164 4004 exclusion phecode
300.9 Posttraumatic stress disorder Mental Disorders 1.15 1.02 – 1.3 0.0204 301 6664 exclusion phecode
301 Personality disorders Mental Disorders 1.14 0.971 – 1.33 0.111 171 3921 exclusion phecode
301.2 Antisocial/borderline personality disorder Mental Disorders 1.2 0.961 – 1.5 0.106 79 2092 exclusion phecode
302 Sexual and gender identity disorders Mental Disorders 0.993 0.944 – 1.04 0.771 1925 10915 exclusion phecode
302.1 Decreased libido Mental Disorders 0.879 0.754 – 1.02 0.0987 177 3470 exclusion phecode
303 Psychogenic and somatoform disorders Mental Disorders 0.996 0.959 – 1.03 0.823 3409 16286 exclusion phecode
303.1 Dissociative disorder Mental Disorders 0.992 0.736 – 1.34 0.958 41 1341 exclusion phecode
303.3 Psychogenic disorder Mental Disorders 0.989 0.951 – 1.03 0.568 3277 16145 exclusion phecode
303.31
Gastrointestinal malfunction arising from
Gastrointestinal malfunction arising from mental factors
 Mental Disorders 1.08 0.931 – 1.25 0.316 199 3797 exclusion phecode
303.4 Somatoform disorder Mental Disorders 1.05 0.959 – 1.15 0.289 493 9373 exclusion phecode
304 Adjustment reaction Mental Disorders 1 0.954 – 1.06 0.859 1629 16704 exclusion phecode
305.2 Eating disorder Mental Disorders 1.16 1.03 – 1.31 0.0123 295 7055 exclusion phecode
306 Other mental disorder Mental Disorders 0.991 0.919 – 1.07 0.821 746 11754 exclusion phecode
306.1 Mental disorders durring/after pregnancy Mental Disorders 1.03 0.922 – 1.16 0.563 348 3198 exclusion phecode
306.9 Tension headache Mental Disorders 0.981 0.866 – 1.11 0.757 266 6138 exclusion phecode
312 Conduct disorders Mental Disorders 1.16 0.946 – 1.41 0.157 96 1803 exclusion phecode
312.3 Impulse control disorder Mental Disorders 1.58 1.14 – 2.18 0.00626 34 542 exclusion phecode
313 Pervasive developmental disorders Mental Disorders 1.06 0.985 – 1.14 0.124 822 10852 exclusion phecode
313.1 Attention deficit hyperactivity disorder Mental Disorders 1.08 1 – 1.16 0.0507 739 9873 exclusion phecode
313.2 Tics and stuttering Mental Disorders 0.866 0.606 – 1.24 0.428 32 560 exclusion phecode
313.3 Autism Mental Disorders 0.73 0.532 – 1 0.0523 40 492 exclusion phecode
315 Develomental delays and disorders Mental Disorders 0.948 0.834 – 1.08 0.416 252 4662 exclusion phecode
315.1 Learning disorder Mental Disorders 1.08 0.798 – 1.46 0.619 38 657 exclusion phecode
315.2 Speech and language disorder Mental Disorders 0.855 0.699 – 1.05 0.127 99 1768 exclusion phecode
316 Substance addiction and disorders Mental Disorders 1.09 1.04 – 1.15 0.000599 1739 23274 exclusion phecode
316.1 Polyneuropathy due to drugs Mental Disorders 0.996 0.893 – 1.11 0.941 354 4313 exclusion phecode
317 Alcohol-related disorders Mental Disorders 1.08 1.02 – 1.15 0.00525 1338 16116 exclusion phecode
317.1 Alcoholism Mental Disorders 1.1 1.03 – 1.17 0.00359 1038 13495 exclusion phecode
317.11 Alcoholic liver damage Mental Disorders 1.06 0.919 – 1.23 0.403 197 2694 exclusion phecode
318 Tobacco use disorder Mental Disorders 1.11 1.08 – 1.15 9.2e-12 4935 24835 exclusion phecode
320 Meningitis Neurological 0.962 0.835 – 1.11 0.593 195 2627 exclusion phecode
323 Encephalitis Neurological 1.09 0.857 – 1.39 0.479 73 1215 exclusion phecode
323.8 Encephalitis, non-infectious Neurological 0.942 0.72 – 1.23 0.664 59 1032 exclusion phecode
324 Other CNS infection and poliomyelitis Neurological 0.992 0.837 – 1.17 0.923 143 1895 exclusion phecode
325
Phlebitis and thrombophlebitis of intracranial
Phlebitis and thrombophlebitis of intracranial venous sinuses
 Neurological 0.995 0.677 – 1.46 0.981 27 338 exclusion phecode
327 Sleep disorders Neurological 0.943 0.42 – 2.12 0.886 0 31602 exclusion phecode
327.1 Hypersomnia Neurological 0.977 0.434 – 2.2 0.955 0 19110 exclusion phecode
327.3 Sleep apnea Neurological 1.08 0.48 – 2.43 0.852 0 31304 exclusion phecode
327.31 Central/nonobstroctive sleep apnea Neurological 1.09 0.454 – 2.62 0.846 0 4784 exclusion phecode
327.32 Obstructive sleep apnea Neurological 0.922 0.411 – 2.07 0.845 0 30530 exclusion phecode
327.4 Insomnia Neurological 1.11 0.494 – 2.48 0.806 0 30960 exclusion phecode
327.41 Organic or persistent insomnia Neurological 0.639 0.275 – 1.48 0.296 0 12120 exclusion phecode
327.5 Parasomnia Neurological 0.948 0.396 – 2.27 0.905 0 5913 exclusion phecode
327.6 Circadian rhythm sleep disorder Neurological 0.936 0.399 – 2.2 0.879 0 2666 exclusion phecode
327.7 Sleep related movement disorders Neurological 1.35 0.58 – 3.14 0.487 0 17323 exclusion phecode
327.71 Restless legs syndrome Neurological 0.919 0.389 – 2.17 0.848 0 15360 exclusion phecode
327.72 Sleep related leg cramps Neurological 0.834 0.357 – 1.95 0.676 0 822 exclusion phecode
331 Other cerebral degenerations Neurological 0.925 0.827 – 1.03 0.171 330 5072 exclusion phecode
331.1 Hydrocephalus Neurological 0.899 0.767 – 1.05 0.187 164 2150 exclusion phecode
331.9 Cerebral degeneration, unspecified Neurological 0.89 0.758 – 1.04 0.155 163 2841 exclusion phecode
332 Parkinson's disease Neurological 1.06 0.901 – 1.26 0.469 146 2876 exclusion phecode
333
Extrapyramidal disease and abnormal movement
Extrapyramidal disease and abnormal movement disorders
 Neurological 1.05 0.963 – 1.14 0.283 576 19081 exclusion phecode
333.1 Essential tremor Neurological 1.05 0.93 – 1.19 0.422 268 4986 exclusion phecode
333.2 Myoclonus Neurological 0.806 0.601 – 1.08 0.152 45 1112 exclusion phecode
333.4 Torsion dystonia Neurological 0.907 0.763 – 1.08 0.266 137 2566 exclusion phecode
333.8 Other degenerative diseases of the basal ganglia Neurological 1.01 0.691 – 1.46 0.976 26 608 exclusion phecode
334 Degenerative disease of the spinal cord Neurological 0.963 0.881 – 1.05 0.405 537 7624 exclusion phecode
334.1 Spinocerebellar disease Neurological 1.14 0.795 – 1.64 0.475 30 587 exclusion phecode
334.2 Anterior horn cell disease Neurological 0.924 0.712 – 1.2 0.553 56 769 exclusion phecode
334.21 Amyotrophic Lateral Sclerosis Neurological 1.06 0.778 – 1.46 0.696 39 497 exclusion phecode
335 Multiple sclerosis Neurological 0.945 0.816 – 1.09 0.448 193 2936 exclusion phecode
337 Disorders of the autonomic nervous system Neurological 1.02 0.909 – 1.14 0.77 328 5286 exclusion phecode
337.1 Peripheral autonomic neuropathy Neurological 0.983 0.823 – 1.17 0.85 125 2110 exclusion phecode
338 Pain Neurological 1.04 1.02 – 1.07 0.000215 11765 19871 exclusion phecode
338.1 Acute pain Neurological 1.03 1.01 – 1.06 0.0139 9209 19785 exclusion phecode
338.2 Chronic pain Neurological 1.08 1.05 – 1.12 3.02e-07 5268 19830 exclusion phecode
339 Other headache syndromes Neurological 1.08 1.04 – 1.11 8.99e-06 4551 25265 exclusion phecode
340 Migraine Neurological 1.07 1.03 – 1.11 0.000504 3394 22538 exclusion phecode
340.1 Migrain with aura Neurological 1.05 0.995 – 1.1 0.0765 1751 17715 exclusion phecode
341
Other demyelinating diseases of central nervous
Other demyelinating diseases of central nervous system
 Neurological 0.965 0.737 – 1.27 0.798 55 998 exclusion phecode
342 Hemiplegia Neurological 0.994 0.854 – 1.16 0.938 180 3282 exclusion phecode
343 Infantile cerebral palsy Neurological 1.01 0.752 – 1.37 0.93 54 663 exclusion phecode
344 Other paralytic syndromes Neurological 0.939 0.838 – 1.05 0.274 325 4928 exclusion phecode
345 Epilepsy, recurrent seizures, convulsions Neurological 1.06 1.01 – 1.13 0.032 1320 18583 exclusion phecode
345.1 Epilepsy Neurological 1.03 0.925 – 1.15 0.57 343 5462 exclusion phecode
345.11 Generalized convulsive epilepsy Neurological 1.01 0.833 – 1.22 0.945 109 1752 exclusion phecode
345.12 Partial epilepsy Neurological 1.03 0.905 – 1.18 0.634 236 3893 exclusion phecode
345.3 Convulsions Neurological 1.07 1.01 – 1.13 0.0307 1230 17476 exclusion phecode
346
Abnormal findings on study of brain and/or
Abnormal findings on study of brain and/or nervous system
 Neurological 0.894 0.718 – 1.11 0.315 79 1300 exclusion phecode
346.1
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of skull and head
 Neurological 0.978 0.902 – 1.06 0.586 642 10425 exclusion phecode
346.2
Nonspecific abnormal results of function study
Nonspecific abnormal results of function study of brain and central nervous system
 Neurological 0.929 0.704 – 1.23 0.602 48 839 exclusion phecode
346.3
Nonspecific abnormal findings in cerebrospinal
Nonspecific abnormal findings in cerebrospinal fluid
 Neurological 1.03 0.778 – 1.37 0.832 47 776 exclusion phecode
347 Cataplexy and narcolepsy Neurological 0.608 0.279 – 1.33 0.212 2 746 exclusion phecode
348 Other conditions of brain Neurological 1.04 0.972 – 1.12 0.241 842 13032 exclusion phecode
348.2 Cerebral edema and compression of brain Neurological 1.03 0.941 – 1.13 0.498 491 6686 exclusion phecode
348.4 Cerebral cysts Neurological 1.04 0.87 – 1.25 0.643 120 1717 exclusion phecode
348.7 Coma Neurological 0.985 0.796 – 1.22 0.887 92 1634 exclusion phecode
348.8 Encephalopathy, not elsewhere classified Neurological 1.14 1.01 – 1.28 0.0275 315 6032 exclusion phecode
348.9 Other conditions of brain, NOS Neurological 1.03 0.973 – 1.09 0.304 1252 16877 exclusion phecode
349
Other and unspecified disorders of the nervous
Other and unspecified disorders of the nervous system
 Neurological 0.953 0.866 – 1.05 0.325 455 6787 exclusion phecode
350 Abnormal movement Neurological 1.01 0.971 – 1.05 0.601 2802 27830 exclusion phecode
350.1 Abnormal involuntary movements Neurological 0.995 0.937 – 1.06 0.858 1150 21512 exclusion phecode
350.2 Abnormality of gait Neurological 1.02 0.966 – 1.07 0.527 1641 21342 exclusion phecode
350.3 Lack of coordination Neurological 0.954 0.863 – 1.05 0.35 422 7456 exclusion phecode
350.5 Abnormal reflex Neurological 1.05 0.841 – 1.31 0.671 85 1369 exclusion phecode
350.6 Disturbances of sensation of smell and taste Neurological 0.988 0.877 – 1.11 0.84 307 3842 exclusion phecode
351 Other peripheral nerve disorders Neurological 1.06 1.03 – 1.1 0.000927 3323 25185 exclusion phecode
352 Disorders of other cranial nerves Neurological 0.985 0.923 – 1.05 0.649 1017 12383 exclusion phecode
352.1 Trigeminal nerve disorders [CN5] Neurological 1.01 0.885 – 1.14 0.92 253 3836 exclusion phecode
352.2 Facial nerve disorders [CN7] Neurological 1 0.907 – 1.1 0.994 460 5668 exclusion phecode
353 Nerve root and plexus disorders Neurological 1.02 0.972 – 1.07 0.451 1998 24247 exclusion phecode
353.1 Nerve plexus lesions Neurological 0.893 0.781 – 1.02 0.0943 232 2888 exclusion phecode
353.2 Nerve root lesions Neurological 0.852 0.658 – 1.1 0.222 63 894 exclusion phecode
355 Complex regional/central pain syndrome Neurological 1.13 0.987 – 1.29 0.0773 227 3840 exclusion phecode
355.1 Chronic pain syndrome Neurological 1.22 1.07 – 1.38 0.00201 263 6060 exclusion phecode
356 Hereditary and idiopathic peripheral neuropathy Neurological 1.06 0.988 – 1.14 0.103 861 14132 exclusion phecode
357 Inflammatory and toxic neuropathy Neurological 1.07 1.02 – 1.13 0.0112 1420 20473 exclusion phecode
358 Myoneural disorders Neurological 1.02 0.923 – 1.13 0.7 412 7778 exclusion phecode
358.1 Myasthenia gravis Neurological 1.21 0.894 – 1.63 0.217 43 747 exclusion phecode
359 Muscular dystrophies and other myopathies Neurological 0.966 0.881 – 1.06 0.471 496 7794 exclusion phecode
359.1 Muscular dystrophies Neurological 0.981 0.706 – 1.36 0.907 37 426 exclusion phecode
359.2 Myopathy Neurological 0.958 0.871 – 1.05 0.378 467 7497 exclusion phecode
360 Disorders of the globe Sense Organs 0.98 0.755 – 1.27 0.878 58 855 exclusion phecode
360.2 Progressive myopia Sense Organs 1.06 0.74 – 1.52 0.747 31 436 exclusion phecode
361 Retinal detachments and defects Sense Organs 0.968 0.87 – 1.08 0.557 370 4720 exclusion phecode
361.1 Retinal detachment with retinal defect Sense Organs 1 0.849 – 1.18 0.998 158 1982 exclusion phecode
362 Other retinal disorders Sense Organs 1.01 0.955 – 1.06 0.794 1629 15592 exclusion phecode
362.2
Degeneration of macula and posterior pole of
Degeneration of macula and posterior pole of retina
 Sense Organs 1.02 0.951 – 1.09 0.636 1002 10425 exclusion phecode
362.21 Macular degeneration, dry Sense Organs 0.966 0.833 – 1.12 0.645 185 2367 exclusion phecode
362.22 Macular degeneration, wet Sense Organs 1.23 0.984 – 1.54 0.0692 76 811 exclusion phecode
362.23 Cystoid macular degeneration of retina Sense Organs 1.04 0.895 – 1.22 0.585 182 2562 exclusion phecode
362.26 Macular puckering of retina Sense Organs 0.977 0.884 – 1.08 0.656 429 5798 exclusion phecode
362.27 Drusen (degenerative) of retina Sense Organs 0.951 0.827 – 1.09 0.487 211 3040 exclusion phecode
362.29 Macular degeneration (senile) of retina NOS Sense Organs 1.06 0.985 – 1.14 0.12 876 9382 exclusion phecode
362.3 Other nondiabetic retinopathy Sense Organs 0.972 0.879 – 1.08 0.583 411 5700 exclusion phecode
362.31 Separation of retinal layers Sense Organs 0.922 0.799 – 1.06 0.262 215 2668 exclusion phecode
362.4 Retinal vascular changes and abnomalities Sense Organs 1.08 0.962 – 1.22 0.188 299 4009 exclusion phecode
362.6 Peripheral retinal degenerations Sense Organs 0.923 0.788 – 1.08 0.315 170 2534 exclusion phecode
362.7 Hereditary retinal dystrophies Sense Organs 1.13 0.944 – 1.35 0.183 122 1407 exclusion phecode
362.8 Retinal hemorrhage/ischemia Sense Organs 0.939 0.775 – 1.14 0.522 113 1588 exclusion phecode
362.9 Retinal edema Sense Organs 0.963 0.804 – 1.15 0.681 132 1899 exclusion phecode
363
Chorioretinal inflammations, scars, and other
Chorioretinal inflammations, scars, and other disorders of choroid
 Sense Organs 0.996 0.869 – 1.14 0.959 234 3222 exclusion phecode
363.3 Chorioretinal scars Sense Organs 1.06 0.893 – 1.26 0.499 144 2169 exclusion phecode
364 Corneal opacity and other disorders of cornea Sense Organs 1.02 0.937 – 1.11 0.634 568 7338 exclusion phecode
364.1 Corneal opacity Sense Organs 0.95 0.819 – 1.1 0.493 191 2575 exclusion phecode
364.2 Corneal edema Sense Organs 0.928 0.716 – 1.2 0.57 60 819 exclusion phecode
364.4 Corneal degenerations Sense Organs 1.09 0.946 – 1.26 0.227 207 2699 exclusion phecode
364.41 Keratoconus Sense Organs 0.948 0.674 – 1.33 0.758 42 479 exclusion phecode
364.5 Corneal dystrophy Sense Organs 0.956 0.834 – 1.09 0.511 233 3149 exclusion phecode
364.51 Fuchs' dystrophy Sense Organs 0.959 0.799 – 1.15 0.657 121 1706 exclusion phecode
364.9 Cornea replaced by transplant Sense Organs 0.975 0.715 – 1.33 0.873 45 597 exclusion phecode
365 Glaucoma Sense Organs 0.959 0.906 – 1.01 0.145 1366 14384 exclusion phecode
365.1 Open-angle glaucoma Sense Organs 0.98 0.876 – 1.1 0.724 332 4367 exclusion phecode
365.11 Primary open angle glaucoma Sense Organs 1.01 0.872 – 1.17 0.906 200 2480 exclusion phecode
365.2 Primary angle-closure glaucoma Sense Organs 1.09 0.908 – 1.31 0.352 125 1592 exclusion phecode
366 Cataract Sense Organs 0.966 0.932 – 1 0.0609 4148 19419 exclusion phecode
366.1 Nonsenile Cataract Sense Organs 1 0.808 – 1.24 0.996 91 1396 exclusion phecode
366.2 Senile cataract Sense Organs 0.923 0.882 – 0.966 0.000549 2379 17252 exclusion phecode
367
Disorders of refraction and accommodation
Disorders of refraction and accommodation; blindness and low vision
 Sense Organs 0.949 0.919 – 0.981 0.00218 4346 27281 exclusion phecode
367.1 Myopia Sense Organs 0.937 0.898 – 0.978 0.0028 2461 25018 exclusion phecode
367.2 Astigmatism Sense Organs 0.935 0.892 – 0.979 0.00453 2004 23245 exclusion phecode
367.8 Hypermetropia Sense Organs 0.942 0.881 – 1.01 0.0857 911 13009 exclusion phecode
367.9 Blindness and low vision Sense Organs 1.05 0.962 – 1.14 0.288 586 8739 exclusion phecode
368 Visual disturbances Sense Organs 0.994 0.954 – 1.04 0.772 2596 27880 exclusion phecode
368.1 Amblyopia Sense Organs 1.02 0.908 – 1.14 0.785 336 4533 exclusion phecode
368.2 Diplopia and disorders of binocular vision Sense Organs 1.09 0.997 – 1.2 0.0581 498 7402 exclusion phecode
368.3 Anisometropia Sense Organs 0.878 0.722 – 1.07 0.189 107 1479 exclusion phecode
368.4 Visual field defects Sense Organs 1.02 0.932 – 1.12 0.65 493 7600 exclusion phecode
368.9 Subjective visual disturbances Sense Organs 0.988 0.891 – 1.09 0.817 391 7345 exclusion phecode
368.91 Psychophysical visual disturbances Sense Organs 1.06 0.739 – 1.53 0.739 30 788 exclusion phecode
369 Infection of the eye Sense Organs 0.909 0.861 – 0.959 0.000522 1464 20301 exclusion phecode
369.2 Eye infection, viral Sense Organs 0.864 0.759 – 0.983 0.0267 248 3512 exclusion phecode
369.5 Conjunctivitis, infectious Sense Organs 0.914 0.862 – 0.969 0.00268 1225 17900 exclusion phecode
370 Keratitis Sense Organs 1.01 0.93 – 1.09 0.839 656 9224 exclusion phecode
370.1 Corneal ulcer Sense Organs 1.09 0.905 – 1.31 0.369 125 1521 exclusion phecode
370.2 Superficial keratitis Sense Organs 0.942 0.826 – 1.07 0.369 249 3805 exclusion phecode
370.3 Keratoconjunctivitis Sense Organs 1.07 0.948 – 1.21 0.273 290 4375 exclusion phecode
370.31 Keratoconjunctivitis sicca Sense Organs 0.817 0.623 – 1.07 0.144 54 1164 exclusion phecode
371 Inflammation of the eye Sense Organs 0.946 0.903 – 0.991 0.0201 2011 22717 exclusion phecode
371.1 Uveitis, noninfectious or NOS Sense Organs 0.975 0.858 – 1.11 0.695 255 3648 exclusion phecode
371.2 Conjunctivitis, noninfectious Sense Organs 0.932 0.841 – 1.03 0.183 399 6293 exclusion phecode
371.21 Allergic conjunctivitis Sense Organs 0.879 0.785 – 0.984 0.0247 334 5272 exclusion phecode
371.3 Inflammation of eyelids Sense Organs 0.937 0.888 – 0.988 0.0159 1514 18819 exclusion phecode
371.33 Noninfectious dermatoses of eyelid Sense Organs 1.12 0.863 – 1.46 0.386 59 912 exclusion phecode
372 Disorders of conjunctiva Sense Organs 0.95 0.87 – 1.04 0.255 543 7370 exclusion phecode
374 Other disorders of eyelids Sense Organs 0.968 0.915 – 1.02 0.252 1358 16792 exclusion phecode
374.1 Ectropion or entropion Sense Organs 0.939 0.822 – 1.07 0.359 242 2826 exclusion phecode
374.2 Lagophthalmos Sense Organs 1.05 0.89 – 1.25 0.545 144 1658 exclusion phecode
374.3 Ptosis of eyelid Sense Organs 0.927 0.846 – 1.02 0.105 497 7400 exclusion phecode
374.6 Dermatochalasis Sense Organs 0.947 0.858 – 1.05 0.287 423 6646 exclusion phecode
375 Disorders of lacrimal system Sense Organs 0.982 0.932 – 1.03 0.49 1595 18358 exclusion phecode
375.1 Dry eyes Sense Organs 0.967 0.919 – 1.02 0.196 1729 18843 exclusion phecode
375.2 Epiphora Sense Organs 0.929 0.809 – 1.07 0.296 212 3082 exclusion phecode
376 Disorders of the orbit Sense Organs 0.998 0.87 – 1.14 0.979 223 2509 exclusion phecode
377 Disorders of optic nerve and visual pathways Sense Organs 1.06 0.962 – 1.16 0.246 473 6403 exclusion phecode
377.1 Optic atrophy Sense Organs 0.941 0.794 – 1.12 0.486 145 1909 exclusion phecode
377.3 Optic neuritis/neuropathy Sense Organs 1.16 1.03 – 1.3 0.0138 308 4126 exclusion phecode
378
Strabismus and other disorders of binocular eye
Strabismus and other disorders of binocular eye movements
 Sense Organs 0.96 0.885 – 1.04 0.335 632 8893 exclusion phecode
378.1 Strabismus (not specified as paralytic) Sense Organs 0.99 0.894 – 1.1 0.844 407 5834 exclusion phecode
378.2 Nystagmus and other irregular eye movements Sense Organs 1.07 0.862 – 1.32 0.555 87 1182 exclusion phecode
378.5 Paralytic strabismus Sense Organs 1.03 0.889 – 1.2 0.67 196 2423 exclusion phecode
379 Other disorders of eye Sense Organs 0.959 0.918 – 1 0.0629 2371 21029 exclusion phecode
379.1 Scleritis and episcleritis Sense Organs 1.01 0.81 – 1.26 0.928 83 1228 exclusion phecode
379.2 Disorders of vitreous body Sense Organs 0.949 0.901 – 1 0.049 1648 16083 exclusion phecode
379.3 Aphakia and other disorders of lens Sense Organs 1.05 0.827 – 1.33 0.693 74 881 exclusion phecode
379.4 Anomalies of pupillary function Sense Organs 0.884 0.738 – 1.06 0.181 132 1989 exclusion phecode
379.5 Disorders of iris and ciliary body Sense Organs 1.11 0.942 – 1.32 0.208 153 2008 exclusion phecode
379.51 Pigmentary iris degeneration Sense Organs 0.763 0.524 – 1.11 0.16 35 517 exclusion phecode
379.9 Pain, swelling or discharge of eye Sense Organs 1.08 0.988 – 1.19 0.0889 492 7883 exclusion phecode
380 Disorders of external ear Sense Organs 0.954 0.895 – 1.02 0.148 1026 13659 exclusion phecode
380.1 Otitis externa Sense Organs 0.949 0.875 – 1.03 0.201 648 9961 exclusion phecode
380.4 Impacted cerumen Sense Organs 0.956 0.901 – 1.01 0.139 1192 15839 exclusion phecode
381 Otitis media and Eustachian tube disorders Sense Organs 1 0.956 – 1.05 0.997 2151 25723 exclusion phecode
381.1 Otitis media Sense Organs 1.03 0.977 – 1.08 0.274 1584 21227 exclusion phecode
381.11 Suppurative and unspecified otitis media Sense Organs 1.02 0.962 – 1.08 0.55 1332 18252 exclusion phecode
381.2 Eustachian tube disorders Sense Organs 0.956 0.89 – 1.03 0.208 854 12424 exclusion phecode
381.3 Mastoiditis & related conditions Sense Organs 1.01 0.822 – 1.24 0.942 100 1043 exclusion phecode
381.9 Otorrhea Sense Organs 1.09 0.948 – 1.26 0.222 213 2616 exclusion phecode
382 Otalgia Sense Organs 0.979 0.912 – 1.05 0.55 831 13266 exclusion phecode
383 Otosclerosis Sense Organs 0.755 0.603 – 0.946 0.0146 84 852 exclusion phecode
384 Other disorders of tympanic membrane Sense Organs 1.03 0.915 – 1.16 0.639 304 3712 exclusion phecode
384.1 Myringitis Sense Organs 1.27 0.869 – 1.86 0.216 28 361 exclusion phecode
384.4 Perforation of tympanic membrane Sense Organs 1.02 0.901 – 1.17 0.709 242 2910 exclusion phecode
385 Other disorders of middle ear and mastoid Sense Organs 0.946 0.839 – 1.07 0.368 295 3069 exclusion phecode
385.3 Cholesteatoma Sense Organs 0.943 0.82 – 1.08 0.414 214 1964 exclusion phecode
385.5
Tympanosclerosis and middle ear disease related
Tympanosclerosis and middle ear disease related to otitis media
 Sense Organs 0.871 0.697 – 1.09 0.224 82 855 exclusion phecode
386
Vertiginous syndromes and other disorders of
Vertiginous syndromes and other disorders of vestibular system
 Sense Organs 0.977 0.908 – 1.05 0.527 792 12768 exclusion phecode
386.1 Meniere's disease Sense Organs 1.02 0.874 – 1.2 0.767 163 2160 exclusion phecode
386.2 Peripheral or central vertigo Sense Organs 0.999 0.922 – 1.08 0.977 643 10774 exclusion phecode
386.21 Central origin vertigo Sense Organs 1.01 0.922 – 1.1 0.855 518 8233 exclusion phecode
386.3 Labyrinthitis Sense Organs 0.977 0.902 – 1.06 0.561 654 10166 exclusion phecode
386.9
Dizziness and giddiness (Light-headedness and
Dizziness and giddiness (Light-headedness and vertigo)
 Sense Organs 0.978 0.941 – 1.02 0.244 3050 27401 exclusion phecode
388 Other disorders of ear Sense Organs 1.06 0.965 – 1.16 0.223 477 6667 exclusion phecode
389 Hearing loss Sense Organs 0.993 0.96 – 1.03 0.684 4197 27094 exclusion phecode
389.1 Sensorineural hearing loss Sense Organs 0.97 0.925 – 1.02 0.219 1880 20075 exclusion phecode
389.2 Conductive hearing loss Sense Organs 0.997 0.913 – 1.09 0.944 548 6415 exclusion phecode
389.3 Degenerative and vascular disorders of ear Sense Organs 0.811 0.651 – 1.01 0.0618 82 1211 exclusion phecode
389.4 Tinnitus Sense Organs 0.927 0.87 – 0.987 0.0187 1063 15207 exclusion phecode
389.5 Disorders of acoustic nerve Sense Organs 0.981 0.767 – 1.26 0.882 62 847 exclusion phecode
394 Rheumatic disease of the heart valves Circulatory System 1.04 0.958 – 1.12 0.375 714 9161 exclusion phecode
394.1 Mitral valve stenosis and aortic valve stenosis Circulatory System 0.932 0.793 – 1.1 0.395 160 2267 exclusion phecode
394.2 Mitral valve disease Circulatory System 1.1 0.956 – 1.26 0.182 228 3097 exclusion phecode
394.3 Aortic valve disease Circulatory System 0.963 0.772 – 1.2 0.738 90 1139 exclusion phecode
394.4 Acute rheumatic heart disease Circulatory System 1.28 0.871 – 1.89 0.207 23 366 exclusion phecode
394.7 Disease of tricuspid valve Circulatory System 1.01 0.891 – 1.14 0.91 291 3892 exclusion phecode
395 Heart valve disorders Circulatory System 1.04 0.99 – 1.09 0.121 2008 19392 exclusion phecode
395.1 Nonrheumatic mitral valve disorders Circulatory System 1.07 1.01 – 1.14 0.0329 1134 13774 exclusion phecode
395.2 Nonrheumatic aortic valve disorders Circulatory System 0.959 0.897 – 1.03 0.22 963 11412 exclusion phecode
395.3 Nonrheumatic tricuspid valve disorders Circulatory System 1.09 0.95 – 1.26 0.213 213 3292 exclusion phecode
395.4 Nonrheumatic pulmonary valve disorders Circulatory System 0.957 0.74 – 1.24 0.739 63 746 exclusion phecode
395.6 Heart valve replaced Circulatory System 0.967 0.888 – 1.05 0.448 583 7289 exclusion phecode
396 Abnormal heart sounds Circulatory System 1.05 1 – 1.09 0.0303 2515 23755 exclusion phecode
401 Hypertension Circulatory System 1.08 1.05 – 1.11 1.2e-08 13289 18287 exclusion phecode
401.1 Essential hypertension Circulatory System 1.08 1.05 – 1.11 1.16e-08 13183 18284 exclusion phecode
401.2 Hypertensive heart and/or renal disease Circulatory System 1.08 1.02 – 1.15 0.0089 1464 11104 exclusion phecode
401.21 Hypertensive heart disease Circulatory System 1.05 0.932 – 1.19 0.41 288 4986 exclusion phecode
401.22 Hypertensive chronic kidney disease Circulatory System 1.09 1.03 – 1.17 0.00599 1153 9923 exclusion phecode
401.3 Other hypertensive complications Circulatory System 1.07 1.01 – 1.14 0.0244 1179 12055 exclusion phecode
411 Ischemic Heart Disease Circulatory System 1.07 1.04 – 1.11 9.32e-05 4283 21384 exclusion phecode
411.1 Unstable angina (intermediate coronary syndrome) Circulatory System 1.03 0.916 – 1.16 0.598 290 5885 exclusion phecode
411.2 Myocardial infarction Circulatory System 1.1 1.05 – 1.16 0.000192 1779 15102 exclusion phecode
411.3 Angina pectoris Circulatory System 1.07 1 – 1.14 0.0405 1001 12713 exclusion phecode
411.4 Coronary atherosclerosis Circulatory System 1.06 1.02 – 1.1 0.00142 3652 19228 exclusion phecode
411.41 Aneurysm and dissection of heart Circulatory System 1.2 0.932 – 1.54 0.158 66 1068 exclusion phecode
411.8
Other chronic ischemic heart disease
Other chronic ischemic heart disease, unspecified
 Circulatory System 1.08 1.04 – 1.13 0.00019 3048 17968 exclusion phecode
411.9
Other acute and subacute forms of ischemic
Other acute and subacute forms of ischemic heart disease
 Circulatory System 1.06 0.898 – 1.24 0.511 157 2913 exclusion phecode
414 Other forms of chronic heart disease Circulatory System 1.01 0.951 – 1.07 0.79 1265 15793 exclusion phecode
414.2 ASCVD Circulatory System 1.03 0.908 – 1.17 0.646 267 4738 exclusion phecode
415 Pulmonary heart disease Circulatory System 1.02 0.971 – 1.08 0.375 1444 20381 exclusion phecode
415.1 Acute pulmonary heart disease Circulatory System 1.04 0.967 – 1.11 0.321 913 12874 exclusion phecode
415.11 Pulmonary embolism and infarction, acute Circulatory System 1.03 0.966 – 1.11 0.327 912 12837 exclusion phecode
415.2 Chronic pulmonary heart disease Circulatory System 1.03 0.954 – 1.12 0.416 631 11728 exclusion phecode
415.21 Primary pulmonary hypertension Circulatory System 1.03 0.899 – 1.18 0.664 220 4675 exclusion phecode
416 Cardiomegaly Circulatory System 0.97 0.885 – 1.06 0.511 508 8340 exclusion phecode
418 Nonspecific chest pain Circulatory System 1.03 1.01 – 1.06 0.0212 5921 25617 exclusion phecode
418.1 Precordial pain Circulatory System 1.04 0.956 – 1.14 0.341 523 10044 exclusion phecode
420 Carditis Circulatory System 0.997 0.924 – 1.08 0.939 734 10420 exclusion phecode
420.1 Myocarditis Circulatory System 0.782 0.583 – 1.05 0.0999 49 633 exclusion phecode
420.2 Pericarditis Circulatory System 1.04 0.931 – 1.15 0.516 383 5632 exclusion phecode
420.21 Acute pericarditis Circulatory System 0.995 0.796 – 1.24 0.961 82 1224 exclusion phecode
420.22 Chronic pericarditis Circulatory System 1.14 0.856 – 1.52 0.368 53 774 exclusion phecode
420.3 Endocarditis Circulatory System 1.01 0.9 – 1.12 0.919 343 4989 exclusion phecode
425 Cardiomyopathy Circulatory System 1.05 0.982 – 1.13 0.149 910 13136 exclusion phecode
425.1 Primary/intrinsic cardiomyopathies Circulatory System 1.06 0.988 – 1.14 0.106 865 12531 exclusion phecode
425.11 Hypertrophic obstructive cardiomyopathy Circulatory System 0.973 0.783 – 1.21 0.804 86 1359 exclusion phecode
425.12 Other hypertrophic cardiomyopathy Circulatory System 0.961 0.775 – 1.19 0.719 90 1328 exclusion phecode
425.2 Secondary/extrinsic cardiomyopathies Circulatory System 1.02 0.86 – 1.21 0.808 134 2144 exclusion phecode
425.8 Other cardiomyopathy Circulatory System 0.907 0.66 – 1.25 0.547 40 625 exclusion phecode
426 Cardiac conduction disorders Circulatory System 1.02 0.986 – 1.05 0.274 6022 19951 exclusion phecode
426.2 Atrioventricular [AV] block Circulatory System 0.987 0.916 – 1.06 0.723 790 8728 exclusion phecode
426.21 First degree AV block Circulatory System 1 0.915 – 1.09 0.985 530 6726 exclusion phecode
426.22 Mobitz II AV block Circulatory System 0.858 0.579 – 1.27 0.445 26 435 exclusion phecode
426.23 Second degree AV block Circulatory System 0.906 0.735 – 1.12 0.355 93 1466 exclusion phecode
426.24 Atrioventricular block, complete Circulatory System 1.05 0.905 – 1.21 0.547 198 2970 exclusion phecode
426.25 Other heart block Circulatory System 0.861 0.692 – 1.07 0.182 84 1379 exclusion phecode
426.3 Bundle branch block Circulatory System 1.07 0.999 – 1.14 0.0542 1067 10598 exclusion phecode
426.31 Right bundle branch block Circulatory System 1.06 0.982 – 1.15 0.131 644 8181 exclusion phecode
426.32 Left bundle branch block Circulatory System 1.08 0.976 – 1.19 0.138 437 6150 exclusion phecode
426.4 Anomalous atrioventricular excitation Circulatory System 0.983 0.737 – 1.31 0.905 50 669 exclusion phecode
426.7 Abnormal electrocardiogram [ECG] [EKG] Circulatory System 1.02 0.984 – 1.05 0.322 4977 19715 exclusion phecode
426.8 Other cardiac conduction disorders Circulatory System 0.948 0.826 – 1.09 0.453 216 5082 exclusion phecode
426.9 Cardiac pacemaker/device in situ Circulatory System 0.996 0.926 – 1.07 0.911 814 8784 exclusion phecode
426.91 Cardiac pacemaker in situ Circulatory System 0.991 0.906 – 1.08 0.85 535 6253 exclusion phecode
426.92 Cardiac defibrillator in situ Circulatory System 0.999 0.895 – 1.11 0.981 351 5566 exclusion phecode
427 Cardiac dysrhythmias Circulatory System 1.01 0.983 – 1.03 0.524 9281 20206 exclusion phecode
427.1 Paroxysmal tachycardia, unspecified Circulatory System 1.02 0.962 – 1.09 0.485 1148 14005 exclusion phecode
427.11 Paroxysmal supraventricular tachycardia Circulatory System 1.05 0.975 – 1.13 0.202 766 11053 exclusion phecode
427.12 Paroxysmal ventricular tachycardia Circulatory System 0.993 0.906 – 1.09 0.879 497 7527 exclusion phecode
427.2 Atrial fibrillation and flutter Circulatory System 1.01 0.968 – 1.06 0.57 2515 14218 exclusion phecode
427.21 Atrial fibrillation Circulatory System 1.01 0.966 – 1.06 0.628 2438 13993 exclusion phecode
427.22 Atrial flutter Circulatory System 0.957 0.885 – 1.04 0.278 693 8353 exclusion phecode
427.3 Other specified cardiac dysrhythmias Circulatory System 1.01 0.972 – 1.04 0.757 4417 20071 exclusion phecode
427.4 Cardiac arrest and ventricular fibrillation Circulatory System 1.05 0.912 – 1.2 0.525 224 4026 exclusion phecode
427.41 Ventricular fibrillation and flutter Circulatory System 0.799 0.649 – 0.985 0.0353 96 1605 exclusion phecode
427.42 Cardiac arrest Circulatory System 1.18 1.01 – 1.38 0.0393 166 3108 exclusion phecode
427.5 Arrhythmia (cardiac) NOS Circulatory System 0.982 0.945 – 1.02 0.349 3246 19984 exclusion phecode
427.6 Premature beats Circulatory System 0.971 0.91 – 1.04 0.368 1049 12328 exclusion phecode
427.61 Supraventricular premature beats Circulatory System 1.01 0.898 – 1.15 0.818 286 4759 exclusion phecode
427.7 Tachycardia NOS Circulatory System 1.03 0.99 – 1.08 0.14 2441 20034 exclusion phecode
427.8 Sinoatrial node dysfunction (Bradycardia) Circulatory System 1 0.905 – 1.11 0.974 405 5702 exclusion phecode
427.9 Palpitations Circulatory System 0.96 0.916 – 1.01 0.0926 1944 19116 exclusion phecode
428 Congestive heart failure; nonhypertensive Circulatory System 1.05 0.997 – 1.1 0.0633 1766 17286 exclusion phecode
428.1 Congestive heart failure (CHF) NOS Circulatory System 1.04 0.986 – 1.1 0.149 1529 16369 exclusion phecode
428.2 Heart failure NOS Circulatory System 1.06 1 – 1.12 0.0334 1484 15851 exclusion phecode
428.3
Heart failure with reduced EF [Systolic or
Heart failure with reduced EF [Systolic or combined heart failure]
 Circulatory System 1.07 0.991 – 1.16 0.0837 681 10526 exclusion phecode
428.4
Heart failure with preserved EF [Diastolic
Heart failure with preserved EF [Diastolic heart failure]
 Circulatory System 1.06 0.974 – 1.16 0.17 523 9749 exclusion phecode
429
Ill-defined descriptions and complications of
Ill-defined descriptions and complications of heart disease
 Circulatory System 1.02 0.992 – 1.05 0.156 6139 24531 exclusion phecode
429.1 Heart transplant/surgery Circulatory System 1.03 0.947 – 1.13 0.459 537 8519 exclusion phecode
429.2 Abnormal function study of cardiovascular system Circulatory System 1.05 1.01 – 1.09 0.0281 2647 21713 exclusion phecode
429.3 Symptoms involving cardiovascular system Circulatory System 1.02 0.983 – 1.05 0.363 4644 24456 exclusion phecode
429.9 Cardiac complications, not elsewhere classified Circulatory System 1.06 0.951 – 1.19 0.278 340 5239 exclusion phecode
430 Intracranial hemorrhage Circulatory System 1.06 0.952 – 1.18 0.294 385 5314 exclusion phecode
430.1 Subarachnoid hemorrhage Circulatory System 0.963 0.809 – 1.15 0.672 136 1784 exclusion phecode
430.2 Intracerebral hemorrhage Circulatory System 1.16 0.996 – 1.36 0.0564 182 2477 exclusion phecode
430.3 Subdural hemorrhage Circulatory System 1.08 0.903 – 1.28 0.409 134 1815 exclusion phecode
433 Cerebrovascular disease Circulatory System 1.06 1.01 – 1.1 0.00868 2768 21705 exclusion phecode
433.1 Occlusion and stenosis of precerebral arteries Circulatory System 1.04 0.976 – 1.12 0.21 943 10676 exclusion phecode
433.11
Occlusion of cerebral arteries, with cerebral
Occlusion of cerebral arteries, with cerebral infarction
 Circulatory System 0.936 0.77 – 1.14 0.503 115 1619 exclusion phecode
433.12 Cerebral atherosclerosis Circulatory System 1.36 0.97 – 1.92 0.0741 32 526 exclusion phecode
433.2 Occlusion of cerebral arteries Circulatory System 1.04 0.976 – 1.1 0.253 1212 14494 exclusion phecode
433.21
Cerebral artery occlusion, with cerebral
Cerebral artery occlusion, with cerebral infarction
 Circulatory System 1.04 0.975 – 1.1 0.259 1169 14072 exclusion phecode
433.3 Cerebral ischemia Circulatory System 1.03 0.974 – 1.09 0.291 1326 15266 exclusion phecode
433.31 Transient cerebral ischemia Circulatory System 1.03 0.971 – 1.1 0.316 1153 13842 exclusion phecode
433.5 Cerebral aneurysm Circulatory System 1.21 1.07 – 1.37 0.00278 286 3179 exclusion phecode
433.6 Acute, but ill-defined cerebrovascular disease Circulatory System 0.94 0.802 – 1.1 0.448 163 2980 exclusion phecode
433.8 Late effects of cerebrovascular disease Circulatory System 0.98 0.866 – 1.11 0.746 280 4642 exclusion phecode
440 Atherosclerosis Circulatory System 1.05 0.988 – 1.12 0.118 1126 13403 exclusion phecode
440.1 Atherosclerosis of renal artery Circulatory System 1.17 0.975 – 1.41 0.0907 126 1600 exclusion phecode
440.2 Atherosclerosis of the extremities Circulatory System 1.06 0.975 – 1.14 0.179 652 9197 exclusion phecode
440.21
Atherosclerosis of native arteries of the
Atherosclerosis of native arteries of the extremities with ulceration or gangrene
 Circulatory System 1.15 0.949 – 1.4 0.153 112 1696 exclusion phecode
440.22
Atherosclerosis of native arteries of the
Atherosclerosis of native arteries of the extremities with intermittent claudication
 Circulatory System 1.04 0.946 – 1.15 0.39 428 6503 exclusion phecode
440.9 Atherosclerosis of aorta Circulatory System 1.08 0.978 – 1.2 0.124 400 5505 exclusion phecode
441 Vascular insufficiency of intestine Circulatory System 1.2 1.06 – 1.37 0.00518 249 3477 exclusion phecode
441.1 Acute vascular insufficiency of intestine Circulatory System 1.06 0.872 – 1.29 0.561 106 1608 exclusion phecode
441.2 Chronic vascular insufficiency of intestine Circulatory System 1.29 1.03 – 1.61 0.0273 74 1042 exclusion phecode
442 Other aneurysm Circulatory System 1.04 0.985 – 1.1 0.159 1434 14577 exclusion phecode
442.1 Aortic aneurysm Circulatory System 1.02 0.955 – 1.09 0.578 1029 11146 exclusion phecode
442.11 Abdominal aortic aneurysm Circulatory System 1.05 0.97 – 1.14 0.213 630 7099 exclusion phecode
442.2 Aneurysm of iliac artery Circulatory System 1.05 0.864 – 1.29 0.604 105 1342 exclusion phecode
442.3 Aneurysm of artery of lower extremity Circulatory System 1.04 0.851 – 1.28 0.679 99 1207 exclusion phecode
442.4 Arterial dissection Circulatory System 1.09 0.859 – 1.38 0.483 76 1274 exclusion phecode
442.8 Aneurysm of other specified artery Circulatory System 1.07 0.93 – 1.23 0.351 223 2744 exclusion phecode
443 Peripheral vascular disease Circulatory System 1.03 0.979 – 1.09 0.226 1433 16981 exclusion phecode
443.1 Raynaud's syndrome Circulatory System 1.01 0.906 – 1.12 0.904 360 5178 exclusion phecode
443.7
Peripheral angiopathy in diseases classified
Peripheral angiopathy in diseases classified elsewhere
 Circulatory System 1.08 0.852 – 1.37 0.528 73 1311 exclusion phecode
443.8 Other specified peripheral vascular diseases Circulatory System 1.06 0.996 – 1.12 0.07 1202 14999 exclusion phecode
443.9 Peripheral vascular disease, unspecified Circulatory System 1.04 0.981 – 1.11 0.175 1073 12750 exclusion phecode
444 Arterial embolism and thrombosis Circulatory System 1.06 0.962 – 1.17 0.238 438 5734 exclusion phecode
444.1
Arterial embolism and thrombosis of lower
Arterial embolism and thrombosis of lower extremity artery
 Circulatory System 1.04 0.885 – 1.21 0.663 176 2042 exclusion phecode
444.2 Embolism and thrombosis of abdominal aorta Circulatory System 1.01 0.804 – 1.26 0.95 79 1042 exclusion phecode
446 Polyarteritis nodosa and allied conditions Circulatory System 1.04 0.906 – 1.2 0.566 218 3138 exclusion phecode
446.4 Wegener's granulomatosis Circulatory System 0.919 0.701 – 1.2 0.538 54 757 exclusion phecode
446.5 Giant cell arteritis Circulatory System 0.962 0.683 – 1.36 0.827 34 534 exclusion phecode
446.9 Arteritis NOS Circulatory System 1.1 0.928 – 1.31 0.265 138 1936 exclusion phecode
447 Other disorders of arteries and arterioles Circulatory System 1.07 1.01 – 1.14 0.0138 1311 15656 exclusion phecode
447.1 Stricture of artery Circulatory System 1.08 0.953 – 1.23 0.222 268 3545 exclusion phecode
447.7 Aortic ectasia Circulatory System 1.06 0.951 – 1.18 0.294 350 5373 exclusion phecode
448 Disease of capillaries Circulatory System 0.922 0.852 – 0.997 0.042 686 8252 exclusion phecode
450 Noninfectious disorders of lymphatic channels Circulatory System 0.97 0.913 – 1.03 0.34 1127 13849 exclusion phecode
451 Phlebitis and thrombophlebitis Circulatory System 1.06 0.948 – 1.18 0.309 334 5335 exclusion phecode
451.2
Phlebitis and thrombophlebitis of lower
Phlebitis and thrombophlebitis of lower extremities
 Circulatory System 1.01 0.834 – 1.22 0.938 116 1775 exclusion phecode
452 Other venous embolism and thrombosis Circulatory System 1.03 0.989 – 1.07 0.15 2645 21968 exclusion phecode
452.1 Iatrogenic pulmonary embolism and infarction Circulatory System 1.09 0.881 – 1.35 0.426 93 2015 exclusion phecode
452.2 Deep vein thrombosis [DVT] Circulatory System 1.06 1.01 – 1.11 0.0287 1775 19583 exclusion phecode
452.8 Postphlebitic syndrome Circulatory System 1.11 0.898 – 1.38 0.33 89 1128 exclusion phecode
453 Chronic venous hypertension Circulatory System 0.984 0.795 – 1.22 0.885 91 1566 exclusion phecode
454 Varicose veins Circulatory System 0.949 0.899 – 1 0.0584 1475 17889 exclusion phecode
454.1 Varicose veins of lower extremity Circulatory System 0.949 0.894 – 1.01 0.0832 1231 15496 exclusion phecode
454.11 Varicose veins of lower extremity, symptomtic Circulatory System 0.956 0.885 – 1.03 0.257 712 10866 exclusion phecode
455 Hemorrhoids Circulatory System 0.984 0.944 – 1.03 0.436 2638 21840 exclusion phecode
456 Chronic venous insufficiency [CVI] Circulatory System 0.969 0.915 – 1.03 0.276 1308 18057 exclusion phecode
457
Encounter for long-term (current) use of
Encounter for long-term (current) use of anticoagulants, antithrombotics, aspirin
 Circulatory System 1.06 0.989 – 1.13 0.105 1045 10924 exclusion phecode
457.2
Encounter for long-term (current) use of
Encounter for long-term (current) use of antiplatelets/antithrombotics
 Circulatory System 1.16 0.979 – 1.37 0.0868 152 2275 exclusion phecode
457.3 Encounter for long-term (current) use of aspirin Circulatory System 1.05 0.986 – 1.13 0.121 983 10471 exclusion phecode
458 Hypotension Circulatory System 1.03 0.988 – 1.08 0.16 2419 22996 exclusion phecode
458.1 Orthostatic hypotension Circulatory System 1.07 0.981 – 1.17 0.127 540 9191 exclusion phecode
458.2 Iatrogenic hypotension Circulatory System 1.09 0.995 – 1.19 0.0653 529 7671 exclusion phecode
458.9 Hypotension NOS Circulatory System 1.03 0.987 – 1.08 0.161 2160 22199 exclusion phecode
459 Other disorders of circulatory system Circulatory System 1.02 0.988 – 1.06 0.208 3895 25118 exclusion phecode
459.1 Hemorrhage NOS Circulatory System 0.917 0.825 – 1.02 0.111 383 5732 exclusion phecode
459.7 Blood vessel replaced Circulatory System 1.03 0.957 – 1.12 0.392 693 9224 exclusion phecode
459.9 Circulatory disease NEC Circulatory System 1.03 0.994 – 1.07 0.105 3236 24102 exclusion phecode
464 Acute sinusitis Respiratory 0.967 0.924 – 1.01 0.147 2061 23729 exclusion phecode
465
Acute upper respiratory infections of multiple
Acute upper respiratory infections of multiple or unspecified sites
 Respiratory 0.961 0.931 – 0.993 0.0166 4540 26439 exclusion phecode
465.2 Acute pharyngitis Respiratory 0.984 0.944 – 1.03 0.462 2616 24073 exclusion phecode
465.4 Acute laryngitis and tracheitis Respiratory 0.984 0.845 – 1.15 0.831 178 3251 exclusion phecode
470 Septal Deviations/Turbinate Hypertrophy Respiratory 0.964 0.896 – 1.04 0.321 787 13544 exclusion phecode
471 Nasal polyps Respiratory 0.892 0.801 – 0.994 0.0389 355 4450 exclusion phecode
472 Chronic pharyngitis and nasopharyngitis Respiratory 0.963 0.891 – 1.04 0.353 678 12872 exclusion phecode
473 Diseases of the larynx and vocal cords Respiratory 0.982 0.931 – 1.04 0.514 1487 18868 exclusion phecode
473.1 Chronic laryngitis Respiratory 1.07 0.763 – 1.51 0.682 28 504 exclusion phecode
473.3 Paralysis/spasm of vocal cords or larynx Respiratory 1.09 0.978 – 1.23 0.117 336 4658 exclusion phecode
473.4 Voice disturbance Respiratory 0.981 0.923 – 1.04 0.527 1160 16357 exclusion phecode
474 Acute and chronic tonsillitis Respiratory 0.918 0.836 – 1.01 0.0756 475 6521 exclusion phecode
474.1 Acute tonsillitis Respiratory 0.883 0.766 – 1.02 0.0861 202 2732 exclusion phecode
474.2 Chronic tonsillitis and adenoiditis Respiratory 0.932 0.838 – 1.04 0.191 368 5347 exclusion phecode
475 Chronic sinusitis Respiratory 0.981 0.937 – 1.03 0.409 2035 21174 exclusion phecode
475.9 Postnasal drip Respiratory 0.942 0.848 – 1.05 0.259 375 6715 exclusion phecode
476 Allergic rhinitis Respiratory 0.973 0.947 – 1 0.0548 6835 21346 exclusion phecode
477 Epistaxis or throat hemorrhage Respiratory 0.95 0.865 – 1.04 0.277 478 8446 exclusion phecode
478 Throat pain Respiratory 0.861 0.743 – 0.997 0.0452 194 3217 exclusion phecode
479 Other upper respiratory disease Respiratory 1 0.963 – 1.05 0.842 2526 21291 exclusion phecode
480 Pneumonia Respiratory 1.02 0.982 – 1.06 0.277 2710 26810 exclusion phecode
480.1 Bacterial pneumonia Respiratory 0.959 0.872 – 1.05 0.382 465 8034 exclusion phecode
480.11 Pneumococcal pneumonia Respiratory 0.959 0.835 – 1.1 0.554 218 3877 exclusion phecode
480.12 Pseudomonal pneumonia Respiratory 0.927 0.723 – 1.19 0.552 64 1072 exclusion phecode
480.13 MRSA pneumonia Respiratory 1.06 0.785 – 1.44 0.687 39 820 exclusion phecode
480.2 Viral pneumonia Respiratory 1.12 0.874 – 1.45 0.36 61 1349 exclusion phecode
480.3 Pneumonia due to fungus (mycoses) Respiratory 0.955 0.734 – 1.24 0.733 57 1132 exclusion phecode
480.5 Bronchopneumonia and lung abscess Respiratory 0.989 0.771 – 1.27 0.932 63 908 exclusion phecode
481 Influenza Respiratory 0.981 0.899 – 1.07 0.669 543 9455 exclusion phecode
483 Acute bronchitis and bronchiolitis Respiratory 0.956 0.903 – 1.01 0.12 1315 21406 exclusion phecode
495 Asthma Respiratory 1.01 0.98 – 1.04 0.482 4643 24524 exclusion phecode
495.1 Chronic obstructive asthma Respiratory 0.931 0.777 – 1.12 0.442 127 2758 exclusion phecode
495.11 Chronic obstructive asthma with exacerbation Respiratory 0.683 0.412 – 1.13 0.139 12 545 exclusion phecode
495.2 Asthma with exacerbation Respiratory 0.943 0.872 – 1.02 0.137 692 11918 exclusion phecode
496 Chronic airway obstruction Respiratory 1.12 1.08 – 1.17 4.28e-08 2650 20124 exclusion phecode
496.1 Emphysema Respiratory 1.16 1.09 – 1.23 5.95e-06 1105 13479 exclusion phecode
496.2 Chronic bronchitis Respiratory 1.13 1.08 – 1.19 4.5e-07 1917 18781 exclusion phecode
496.21 Obstructive chronic bronchitis Respiratory 1.14 1.08 – 1.2 5.14e-07 1725 17871 exclusion phecode
496.3 Bronchiectasis Respiratory 0.886 0.776 – 1.01 0.0757 241 3804 exclusion phecode
497 Bronchitis Respiratory 0.986 0.917 – 1.06 0.711 788 13461 exclusion phecode
498 Acute bronchospasm Respiratory 0.953 0.82 – 1.11 0.527 182 3604 exclusion phecode
499 Cystic fibrosis Respiratory 0.887 0.697 – 1.13 0.331 70 1039 exclusion phecode
500 Lung disease due to external agents Respiratory 0.933 0.824 – 1.06 0.274 283 3785 exclusion phecode
500.1 Extrinsic allergic alveolitis Respiratory 1.03 0.739 – 1.44 0.861 33 631 exclusion phecode
500.2 Pneumoconiosis Respiratory 0.683 0.492 – 0.947 0.0223 40 531 exclusion phecode
501 Pneumonitis due to inhalation of food or vomitus Respiratory 1.04 0.917 – 1.17 0.563 273 4257 exclusion phecode
502 Postinflammatory pulmonary fibrosis Respiratory 0.968 0.866 – 1.08 0.569 344 5592 exclusion phecode
503 Pulmonary congestion and hypostasis Respiratory 0.955 0.851 – 1.07 0.432 318 5663 exclusion phecode
504 Other alveolar and parietoalveolar pneumonopathy Respiratory 0.894 0.778 – 1.03 0.116 220 4012 exclusion phecode
504.1 Idiopathic fibrosing alveolitis Respiratory 0.956 0.777 – 1.18 0.669 97 2111 exclusion phecode
505 Other pulmonary inflamation or edema Respiratory 1.05 0.968 – 1.13 0.251 687 10803 exclusion phecode
506 Empyema and pneumothorax Respiratory 0.994 0.944 – 1.05 0.82 1600 17566 exclusion phecode
507 Pleurisy; pleural effusion Respiratory 1.01 0.952 – 1.06 0.841 1415 18143 exclusion phecode
508
Pulmonary collapse; interstitial and
Pulmonary collapse; interstitial and compensatory emphysema
 Respiratory 1.05 0.983 – 1.11 0.152 1094 15620 exclusion phecode
509 Respiratory failure, insufficiency, arrest Respiratory 1.07 1.02 – 1.13 0.00573 1695 20514 exclusion phecode
509.1 Respiratory failure Respiratory 1.11 1.03 – 1.2 0.00493 748 13079 exclusion phecode
509.2 Respiratory insufficiency Respiratory 1.02 0.925 – 1.12 0.721 458 8069 exclusion phecode
509.3
Pulmonary insufficiency or respiratory failure
Pulmonary insufficiency or respiratory failure following trauma and surgery
 Respiratory 1.1 1.02 – 1.18 0.0122 820 11433 exclusion phecode
509.8
Dependence on respirator [Ventilator] or
Dependence on respirator [Ventilator] or supplemental oxygen
 Respiratory 1.11 1.02 – 1.21 0.0152 543 11824 exclusion phecode
510 Other diseases of lung Respiratory 0.993 0.953 – 1.03 0.748 2650 24582 exclusion phecode
510.2 Lung transplant Respiratory 0.977 0.737 – 1.29 0.87 50 1184 exclusion phecode
512 Other symptoms of respiratory system Respiratory 1.01 0.984 – 1.03 0.5 9017 22633 exclusion phecode
512.1 Wheezing Respiratory 0.978 0.891 – 1.07 0.646 465 10668 exclusion phecode
512.2 Painful respiration Respiratory 1.03 0.964 – 1.11 0.365 889 16983 exclusion phecode
512.3 Abnormal chest sounds Respiratory 1.03 0.847 – 1.25 0.762 101 2246 exclusion phecode
512.7 Shortness of breath Respiratory 1.03 1 – 1.07 0.0455 4264 22565 exclusion phecode
512.8 Cough Respiratory 0.993 0.96 – 1.03 0.692 4129 22628 exclusion phecode
512.9 Other dyspnea Respiratory 0.992 0.96 – 1.03 0.649 4289 22585 exclusion phecode
513 Respiratory abnormalities Respiratory 1.02 0.987 – 1.05 0.276 5625 26003 exclusion phecode
513.3 Hypoventilation Respiratory 1.02 0.872 – 1.2 0.793 162 6405 exclusion phecode
513.31 Apnea Respiratory 1.17 0.892 – 1.53 0.258 50 3411 exclusion phecode
513.32 Orthopnea Respiratory 1.09 0.835 – 1.42 0.525 57 1580 exclusion phecode
513.4 Hyperventilation Respiratory 1.16 1.01 – 1.33 0.0391 211 3891 exclusion phecode
513.8 Disorders of diaphragm Respiratory 0.853 0.7 – 1.04 0.115 103 1923 exclusion phecode
514 Abnormal findings examination of lungs Respiratory 1 0.966 – 1.04 0.827 2902 23479 exclusion phecode
514.1
Abnormal results of function study of pulmonary
Abnormal results of function study of pulmonary system
 Respiratory 1.24 0.991 – 1.55 0.0603 80 1713 exclusion phecode
514.2 Solitary pulmonary nodule Respiratory 0.994 0.945 – 1.05 0.831 1647 18146 exclusion phecode
516 Abnormal sputum Respiratory 0.949 0.845 – 1.07 0.376 308 4787 exclusion phecode
516.1 Hemoptysis Respiratory 0.961 0.845 – 1.09 0.543 255 3972 exclusion phecode
519
Other diseases of respiratory system, not
Other diseases of respiratory system, not elsewhere classified
 Respiratory 1 0.968 – 1.04 0.815 3248 27380 exclusion phecode
519.1 Tracheostomy complications Respiratory 1.06 0.872 – 1.28 0.571 118 1466 exclusion phecode
519.2 Respiratory complications Respiratory 1.07 0.931 – 1.23 0.338 221 3080 exclusion phecode
519.8 Other diseases of respiratory system, NEC Respiratory 0.963 0.893 – 1.04 0.333 728 10864 exclusion phecode
519.9
Symptoms involving respiratory system and other
Symptoms involving respiratory system and other chest symptoms
 Respiratory 1.01 0.972 – 1.06 0.519 2384 23773 exclusion phecode
520 Disorders of tooth development Digestive 1.09 0.956 – 1.25 0.194 237 2684 exclusion phecode
520.1 Hereditary disturbances in tooth structure Digestive 1.12 0.911 – 1.37 0.286 108 1116 exclusion phecode
520.2 Disturbances in tooth eruption Digestive 1.1 0.923 – 1.3 0.297 140 1657 exclusion phecode
521 Diseases of hard tissues of teeth Digestive 1.12 1.03 – 1.23 0.0121 512 6171 exclusion phecode
521.1 Dental caries Digestive 1.11 1.01 – 1.22 0.0296 475 5732 exclusion phecode
521.2 Dental abrasion, erosion and attrition Digestive 1.35 0.924 – 1.98 0.121 28 364 exclusion phecode
522 Diseases of pulp and periapical tissues Digestive 1.07 0.938 – 1.23 0.306 228 3686 exclusion phecode
522.5 Periapical abscess Digestive 1.08 0.937 – 1.25 0.284 191 3161 exclusion phecode
523 Gingival and periodontal diseases Digestive 1.06 0.953 – 1.18 0.281 362 4900 exclusion phecode
523.1 Gingivitis Digestive 0.919 0.727 – 1.16 0.483 71 980 exclusion phecode
523.3 Periodontitis (acute or chronic) Digestive 1.13 0.971 – 1.32 0.114 178 2475 exclusion phecode
523.31 Acute periodontitis Digestive 1.1 0.935 – 1.29 0.254 157 2136 exclusion phecode
523.32 Chronic periodontitis Digestive 0.994 0.774 – 1.28 0.961 65 791 exclusion phecode
524 Dentofacial anomalies, including malocclusion Digestive 0.96 0.835 – 1.1 0.56 216 2734 exclusion phecode
524.3 Anomalies of tooth position/malocclusion Digestive 0.904 0.754 – 1.08 0.274 124 1739 exclusion phecode
525
Other diseases of the teeth and supporting
Other diseases of the teeth and supporting structures
 Digestive 1.04 0.956 – 1.14 0.336 536 7257 exclusion phecode
525.1 Loss of teeth or edentulism Digestive 1.04 0.903 – 1.19 0.604 219 2619 exclusion phecode
526 Diseases of the jaws Digestive 0.983 0.93 – 1.04 0.53 1433 18571 exclusion phecode
526.1 Cysts of the jaws Digestive 1.01 0.868 – 1.18 0.863 172 1723 exclusion phecode
526.3 Anomalies of jaw size/symmetry Digestive 0.834 0.7 – 0.993 0.0415 132 1876 exclusion phecode
526.4 Temporomandibular joint disorders Digestive 1.01 0.933 – 1.08 0.889 757 10617 exclusion phecode
526.41 Temporomandibular joint disorder, unspecified Digestive 1.03 0.945 – 1.12 0.526 604 8418 exclusion phecode
526.42 Arthralgia/ankylosis of temporomandibular joint Digestive 0.985 0.889 – 1.09 0.771 399 5402 exclusion phecode
526.5 Inflammatory conditions of jaw Digestive 0.949 0.813 – 1.11 0.508 179 1936 exclusion phecode
526.8 Exostosis of jaw Digestive 0.914 0.64 – 1.3 0.619 32 337 exclusion phecode
526.9 Jaw disease NOS Digestive 1 0.889 – 1.13 0.97 306 3325 exclusion phecode
527 Diseases of the salivary glands Digestive 0.996 0.931 – 1.07 0.905 950 11914 exclusion phecode
527.1 Hypertrophy of salivary gland Digestive 1.16 0.809 – 1.67 0.416 32 368 exclusion phecode
527.2 Sialoadenitis Digestive 0.889 0.768 – 1.03 0.114 203 2653 exclusion phecode
527.7 Disturbance of salivary secretion Digestive 1.01 0.914 – 1.11 0.909 459 6239 exclusion phecode
527.8 Other specified diseases of the salivary glands Digestive 1.11 0.938 – 1.31 0.223 158 1662 exclusion phecode
528
Diseases of the oral soft tissues, excluding
Diseases of the oral soft tissues, excluding lesions specific for gingiva and tongue
 Digestive 0.917 0.868 – 0.969 0.00218 1396 17850 exclusion phecode
528.1 Stomatitis and mucositis Digestive 0.872 0.778 – 0.979 0.02 319 4603 exclusion phecode
528.11 Stomatitis and mucositis (ulcerative) Digestive 0.872 0.715 – 1.06 0.176 104 1492 exclusion phecode
528.12 Oral aphthae Digestive 0.982 0.796 – 1.21 0.865 87 1495 exclusion phecode
528.3 Cellulitis and abscess of oral soft tissues Digestive 0.885 0.737 – 1.06 0.19 128 1582 exclusion phecode
528.4 Cysts of oral soft tissues Digestive 1.01 0.789 – 1.28 0.956 77 829 exclusion phecode
528.41 Cyst of the salivary gland Digestive 1.02 0.766 – 1.37 0.877 53 534 exclusion phecode
528.5 Diseases of lips Digestive 0.785 0.685 – 0.899 0.000497 225 3099 exclusion phecode
528.6 Leukoplakia of oral mucosa Digestive 0.864 0.695 – 1.07 0.185 89 919 exclusion phecode
528.7 Sialolithiasis Digestive 0.848 0.683 – 1.05 0.139 95 1087 exclusion phecode
529 Diseases and other conditions of the tongue Digestive 0.993 0.89 – 1.11 0.905 349 4594 exclusion phecode
529.1 Glossitis Digestive 0.991 0.776 – 1.27 0.945 63 868 exclusion phecode
529.6 Glossodynia Digestive 0.905 0.722 – 1.13 0.387 82 1100 exclusion phecode
530 Diseases of esophagus Digestive 1.07 1.04 – 1.1 1.36e-07 8992 21501 exclusion phecode
530.1 Esophagitis, GERD and related diseases Digestive 1.07 1.05 – 1.1 4.59e-08 8628 21501 exclusion phecode
530.11 GERD Digestive 1.08 1.05 – 1.11 2.05e-08 8367 21500 exclusion phecode
530.12 Ulcer of esophagus Digestive 1.13 0.963 – 1.32 0.137 175 2931 exclusion phecode
530.13 Barrett's esophagus Digestive 0.984 0.884 – 1.1 0.769 363 5485 exclusion phecode
530.14 Reflux esophagitis Digestive 1.02 0.95 – 1.1 0.534 742 13076 exclusion phecode
530.15 Eosinophilic esophagitis Digestive 1.03 0.855 – 1.24 0.75 127 1686 exclusion phecode
530.2 Esophageal bleeding (varices/hemorrhage) Digestive 0.994 0.886 – 1.12 0.923 318 4752 exclusion phecode
530.3 Stricture and stenosis of esophagus Digestive 1.01 0.921 – 1.11 0.827 490 6671 exclusion phecode
530.5 Disorders of esophageal motility Digestive 1.02 0.9 – 1.16 0.721 246 4052 exclusion phecode
530.6 Diverticulum of esophagus, acquired Digestive 0.967 0.773 – 1.21 0.768 89 931 exclusion phecode
530.7 Gastroesophageal laceration-hemorrhage syndrome Digestive 1 0.735 – 1.37 0.979 38 601 exclusion phecode
530.9 Heartburn Digestive 1.01 0.93 – 1.09 0.861 661 11261 exclusion phecode
531 Peptic ulcer (excl. esophageal) Digestive 1.08 1.01 – 1.15 0.024 965 13693 exclusion phecode
531.1 Hemorrhage from gastrointestinal ulcer Digestive 1.06 0.906 – 1.23 0.479 173 2507 exclusion phecode
531.2 Gastric ulcer Digestive 1.08 0.986 – 1.17 0.101 544 7924 exclusion phecode
531.3 Duodenal ulcer Digestive 1.02 0.894 – 1.17 0.735 224 3024 exclusion phecode
531.4 Peptic ulcer, site unspecified Digestive 1.11 0.989 – 1.24 0.0764 323 5267 exclusion phecode
531.5 Gastrojejunal ulcer Digestive 1.17 0.908 – 1.5 0.229 67 1031 exclusion phecode
532 Dysphagia Digestive 1.05 1.01 – 1.09 0.0155 2804 20571 exclusion phecode
535 Gastritis and duodenitis Digestive 1.05 0.99 – 1.11 0.107 1255 19104 exclusion phecode
535.1 Acute gastritis Digestive 1.07 0.979 – 1.17 0.137 533 8143 exclusion phecode
535.2 Atrophic gastritis Digestive 0.994 0.844 – 1.17 0.943 152 2439 exclusion phecode
535.6 Duodenitis Digestive 1.01 0.855 – 1.19 0.926 153 2273 exclusion phecode
535.8 Other specified gastritis Digestive 0.94 0.826 – 1.07 0.356 245 4386 exclusion phecode
535.9 Gastritis and duodenitis, NOS Digestive 1.01 0.925 – 1.1 0.833 543 8703 exclusion phecode
536 Disorders of function of stomach Digestive 1.01 0.951 – 1.07 0.798 1261 19432 exclusion phecode
536.3 Gastroparesis Digestive 1.16 1.02 – 1.31 0.0186 277 4719 exclusion phecode
536.7
Complications of gastrostomy, colostomy and
Complications of gastrostomy, colostomy and enterostomy
 Digestive 1.06 0.92 – 1.23 0.409 202 2844 exclusion phecode
536.8
Dyspepsia and other specified disorders of
Dyspepsia and other specified disorders of function of stomach
 Digestive 0.975 0.911 – 1.04 0.474 897 14687 exclusion phecode
537 Other disorders of stomach and duodenum Digestive 1.08 1.02 – 1.14 0.00704 1358 20957 exclusion phecode
537.1 Lesions of stomach and duodenum Digestive 1.22 0.948 – 1.57 0.123 63 1118 exclusion phecode
539 Bariatric surgery Digestive 1.1 1 – 1.21 0.0391 471 10283 exclusion phecode
540 Appendiceal conditions Digestive 1.06 0.937 – 1.21 0.336 259 3369 exclusion phecode
540.1 Appendicitis Digestive 1.05 0.92 – 1.21 0.449 219 2891 exclusion phecode
540.11 Acute appendicitis Digestive 1.06 0.914 – 1.23 0.436 184 2398 exclusion phecode
550 Abdominal hernia Digestive 1.06 1.02 – 1.09 0.00304 3549 26166 exclusion phecode
550.1 Inguinal hernia Digestive 0.984 0.922 – 1.05 0.626 1032 11031 exclusion phecode
550.2 Diaphragmatic hernia Digestive 1.07 1.01 – 1.13 0.0208 1329 17413 exclusion phecode
550.3 Femoral hernia Digestive 1.07 0.857 – 1.35 0.533 79 877 exclusion phecode
550.4 Umbilical hernia Digestive 1.08 0.991 – 1.17 0.0808 621 8903 exclusion phecode
550.5 Ventral hernia Digestive 1.11 1.04 – 1.18 0.00108 1147 15008 exclusion phecode
550.6 Incisional hernia Digestive 1.06 0.975 – 1.15 0.18 631 8905 exclusion phecode
555
Inflammatory bowel disease and other
Inflammatory bowel disease and other gastroenteritis and colitis
 Digestive 1.07 0.997 – 1.14 0.0607 899 11637 exclusion phecode
555.1 Regional enteritis Digestive 1.04 0.951 – 1.14 0.393 534 7044 exclusion phecode
555.2 Ulcerative colitis Digestive 1.05 0.96 – 1.14 0.296 553 7140 exclusion phecode
555.21 Ulcerative colitis (chronic) Digestive 1.01 0.898 – 1.13 0.89 314 4145 exclusion phecode
556 Ulceration of the lower GI tract Digestive 1.06 0.935 – 1.19 0.383 283 4691 exclusion phecode
556.1 Ulceration of intestine Digestive 1.07 0.94 – 1.22 0.309 245 4100 exclusion phecode
556.11
Angiodysplasia of intestine (without mention of
Angiodysplasia of intestine (without mention of hemorrhage)
 Digestive 0.951 0.764 – 1.18 0.653 85 1506 exclusion phecode
557 Intestinal malabsorption (non-celiac) Digestive 1.05 0.972 – 1.13 0.213 707 12820 exclusion phecode
557.1 Celiac disease Digestive 0.955 0.836 – 1.09 0.498 243 3133 exclusion phecode
558 Noninfectious gastroenteritis Digestive 1.1 1.05 – 1.16 0.000134 1625 20301 exclusion phecode
559 Ileostomy status Digestive 1.01 0.933 – 1.1 0.743 600 7238 exclusion phecode
560 Intestinal obstruction without mention of hernia Digestive 1.03 0.979 – 1.09 0.242 1622 18787 exclusion phecode
560.1 Paralytic ileus Digestive 1.04 0.967 – 1.11 0.315 899 11687 exclusion phecode
560.2 Impaction of intestine Digestive 1.12 0.954 – 1.31 0.167 166 2897 exclusion phecode
560.3 Peritoneal or intestinal adhesions Digestive 1.03 0.868 – 1.22 0.749 137 1969 exclusion phecode
560.4 Other intestinal obstruction Digestive 1 0.934 – 1.07 0.992 881 12189 exclusion phecode
561 Symptoms involving digestive system Digestive 1.04 0.981 – 1.1 0.186 1208 16650 exclusion phecode
562 Diverticulosis and diverticulitis Digestive 1.02 0.982 – 1.07 0.28 2897 17434 exclusion phecode
562.1 Diverticulosis Digestive 1.02 0.982 – 1.07 0.275 2870 17401 exclusion phecode
562.2 Diverticulitis Digestive 1.04 0.97 – 1.12 0.248 767 11173 exclusion phecode
564 Functional digestive disorders Digestive 1.05 1.02 – 1.08 0.00131 5778 22006 exclusion phecode
564.1 Irritable Bowel Syndrome Digestive 1.07 1.02 – 1.13 0.00966 1617 17203 exclusion phecode
564.9 Personal history of diseases of digestive system Digestive 1.03 0.979 – 1.09 0.243 1522 19646 exclusion phecode
565 Anal and rectal conditions Digestive 1.01 0.958 – 1.06 0.788 1692 21910 exclusion phecode
565.1 Anal and rectal polyp Digestive 1.04 0.956 – 1.13 0.363 587 8670 exclusion phecode
567 Peritonitis and retroperitoneal infections Digestive 1.05 0.971 – 1.13 0.228 709 9608 exclusion phecode
568 Other disorders of peritoneum Digestive 1.07 1 – 1.14 0.036 980 12077 exclusion phecode
568.1
Peritoneal adhesions (postoperative)
Peritoneal adhesions (postoperative) (postinfection)
 Digestive 1.08 1 – 1.16 0.0478 745 8805 exclusion phecode
569 Other disorders of intestine Digestive 1.03 0.997 – 1.07 0.0778 3962 25434 exclusion phecode
569.1 Toxic gastroenteritis and colitis Digestive 0.946 0.804 – 1.11 0.499 151 2297 exclusion phecode
569.2 Gastrointestinal complications Digestive 1.02 0.939 – 1.1 0.695 694 9848 exclusion phecode
571 Chronic liver disease and cirrhosis Digestive 1.06 1.01 – 1.1 0.0175 2123 23398 exclusion phecode
571.5 Other chronic nonalcoholic liver disease Digestive 1.05 1.01 – 1.1 0.0281 1990 23120 exclusion phecode
571.51 Cirrhosis of liver without mention of alcohol Digestive 1.06 0.963 – 1.16 0.246 490 7049 exclusion phecode
571.6 Primary biliary cirrhosis Digestive 0.999 0.805 – 1.24 0.996 91 1261 exclusion phecode
571.8
Liver abscess and sequelae of chronic liver
Liver abscess and sequelae of chronic liver disease
 Digestive 1.05 0.95 – 1.15 0.359 467 6602 exclusion phecode
571.81 Portal hypertension Digestive 1.06 0.94 – 1.2 0.329 285 3976 exclusion phecode
572 Ascites (non malignant) Digestive 1.04 0.983 – 1.1 0.173 1257 16106 exclusion phecode
573 Other disorders of liver Digestive 1.03 0.987 – 1.07 0.182 2774 24245 exclusion phecode
573.1 Chronic passive congestion of liver Digestive 0.925 0.697 – 1.23 0.588 47 999 exclusion phecode
573.2 Liver replaced by transplant Digestive 1.11 0.928 – 1.34 0.245 128 2044 exclusion phecode
573.3 Hepatomegaly Digestive 1.1 0.965 – 1.25 0.158 253 3298 exclusion phecode
573.4 Acute and subacute necrosis of liver Digestive 0.977 0.82 – 1.16 0.798 141 2249 exclusion phecode
573.5 Jaundice (not of newborn) Digestive 1.02 0.927 – 1.11 0.736 512 6673 exclusion phecode
573.6
Nonspecific elevation of levels of transaminase
Nonspecific elevation of levels of transaminase or lactic acid dehydrogenase [LDH]
 Digestive 1.02 0.963 – 1.08 0.473 1177 18873 exclusion phecode
573.7 Abnormal results of function study of liver Digestive 0.997 0.941 – 1.06 0.917 1253 19714 exclusion phecode
573.9 Abnormal serum enzyme levels Digestive 1 0.959 – 1.05 0.89 2072 24482 exclusion phecode
574 Cholelithiasis and cholecystitis Digestive 0.984 0.935 – 1.04 0.552 1589 21044 exclusion phecode
574.1 Cholelithiasis Digestive 0.971 0.92 – 1.03 0.289 1445 19706 exclusion phecode
574.11 Cholelithiasis with acute cholecystitis Digestive 0.779 0.66 – 0.919 0.00303 158 2283 exclusion phecode
574.12 Cholelithiasis with other cholecystitis Digestive 0.918 0.811 – 1.04 0.18 272 3741 exclusion phecode
574.2 Calculus of bile duct Digestive 0.961 0.868 – 1.06 0.438 405 5878 exclusion phecode
574.3 Cholecystitis without cholelithiasis Digestive 0.932 0.84 – 1.03 0.18 389 5490 exclusion phecode
575 Other biliary tract disease Digestive 1.01 0.947 – 1.07 0.845 1161 15309 exclusion phecode
575.1 Cholangitis Digestive 0.939 0.812 – 1.09 0.398 197 2383 exclusion phecode
575.2 Obstruction of bile duct Digestive 0.982 0.881 – 1.1 0.745 356 4125 exclusion phecode
575.6 Cholesterolosis of gallbladder Digestive 0.977 0.806 – 1.18 0.814 111 1406 exclusion phecode
575.7 Other disorders of gallbladder Digestive 1 0.913 – 1.11 0.922 448 6360 exclusion phecode
575.8 Other disorders of biliary tract Digestive 0.99 0.91 – 1.08 0.821 601 7776 exclusion phecode
575.9
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of biliary tract
 Digestive 0.921 0.77 – 1.1 0.37 126 1757 exclusion phecode
577 Diseases of pancreas Digestive 1.02 0.956 – 1.08 0.625 1177 14525 exclusion phecode
577.1 Acute pancreatitis Digestive 1.01 0.929 – 1.1 0.814 590 7947 exclusion phecode
577.2 Chronic pancreatitis Digestive 1.12 0.983 – 1.27 0.09 255 3280 exclusion phecode
577.3 Cyst and pseudocyst of pancreas Digestive 1.09 0.968 – 1.22 0.159 316 3596 exclusion phecode
578 Gastrointestinal hemorrhage Digestive 1.05 1.01 – 1.1 0.0275 2021 26415 exclusion phecode
578.1 Hematemesis Digestive 1.09 0.945 – 1.25 0.242 210 3378 exclusion phecode
578.2 Blood in stool Digestive 1.04 0.978 – 1.1 0.221 1165 18575 exclusion phecode
578.8 Hemorrhage of rectum and anus Digestive 1.06 0.99 – 1.13 0.093 942 15373 exclusion phecode
578.9 Hemorrhage of gastrointestinal tract Digestive 1.07 0.989 – 1.16 0.0902 662 10617 exclusion phecode
579 Other symptoms involving abdomen and pelvis Digestive 1.03 0.984 – 1.07 0.212 2291 24368 exclusion phecode
579.2 Splenomegaly Digestive 1.01 0.902 – 1.13 0.85 325 5112 exclusion phecode
579.8 Nonspecific abnormal findings in stool contents Digestive 1 0.918 – 1.09 0.985 556 9590 exclusion phecode
580 Nephritis; nephrosis; renal sclerosis Genitourinary 1.05 0.978 – 1.13 0.178 849 10883 exclusion phecode
580.1 Glomerulonephritis Genitourinary 1.03 0.884 – 1.21 0.682 178 2769 exclusion phecode
580.11 Proliferative glomerulonephritis Genitourinary 1.1 0.869 – 1.39 0.436 81 1008 exclusion phecode
580.12 Non-proliferative glomerulonephritis Genitourinary 0.969 0.74 – 1.27 0.819 55 800 exclusion phecode
580.13 Acute glomerulonephritis, NOS Genitourinary 0.986 0.647 – 1.5 0.949 22 425 exclusion phecode
580.14 Chronic glomerulonephritis, NOS Genitourinary 0.959 0.794 – 1.16 0.664 123 1931 exclusion phecode
580.2
Nephrotic syndrome without mention of
Nephrotic syndrome without mention of glomerulonephritis
 Genitourinary 1.11 0.901 – 1.36 0.331 102 1543 exclusion phecode
580.3
Nephritis and nephropathy without mention of
Nephritis and nephropathy without mention of glomerulonephritis
 Genitourinary 1.04 0.963 – 1.13 0.293 641 8386 exclusion phecode
580.31
Nephritis and nephropathy in diseases
Nephritis and nephropathy in diseases classified elsewhere
 Genitourinary 1.04 0.934 – 1.16 0.479 387 5001 exclusion phecode
580.32
Nephritis and nephropathy with pathological
Nephritis and nephropathy with pathological lesion
 Genitourinary 1.04 0.923 – 1.16 0.553 322 4620 exclusion phecode
580.4 Renal sclerosis, NOS Genitourinary 1.15 0.992 – 1.34 0.0638 196 2356 exclusion phecode
585 Renal failure Genitourinary 1.07 1.03 – 1.11 0.000241 3641 23150 exclusion phecode
585.1 Acute renal failure Genitourinary 1.09 1.04 – 1.14 0.000706 1883 19216 exclusion phecode
585.2 Renal failure NOS Genitourinary 1.01 0.907 – 1.13 0.829 356 5718 exclusion phecode
585.3 Chronic renal failure [CKD] Genitourinary 1.07 1.02 – 1.11 0.00242 2681 20825 exclusion phecode
585.31 Renal dialysis Genitourinary 1.06 0.948 – 1.18 0.308 353 5164 exclusion phecode
585.32 End stage renal disease Genitourinary 1.05 0.959 – 1.15 0.282 492 6853 exclusion phecode
585.33 Chronic Kidney Disease, Stage III Genitourinary 1.05 0.996 – 1.11 0.0703 1380 14796 exclusion phecode
585.34 Chronic Kidney Disease, Stage IV Genitourinary 1.12 1.02 – 1.23 0.0225 438 6419 exclusion phecode
585.4 Chronic kidney disease, Stage I or II Genitourinary 1.08 0.985 – 1.18 0.1 509 7825 exclusion phecode
586 Other disorders of the kidney and ureters Genitourinary 1.05 1.01 – 1.08 0.00945 4118 24729 exclusion phecode
586.1 Anatomical abnormatilies of kidney and ureters Genitourinary 1.17 1.01 – 1.36 0.0343 210 2495 exclusion phecode
586.11 Small kidney Genitourinary 1.17 0.969 – 1.41 0.102 127 1461 exclusion phecode
586.12 Vesicoureteral reflux Genitourinary 1.19 0.951 – 1.5 0.128 82 1045 exclusion phecode
586.2 Cyst of kidney, acquired Genitourinary 0.965 0.893 – 1.04 0.374 700 8907 exclusion phecode
586.3 Vascular disorders of kidney/hypertrophy Genitourinary 0.869 0.701 – 1.08 0.201 91 1309 exclusion phecode
586.4 Stricture/obstruction of ureter Genitourinary 1 0.943 – 1.07 0.921 1124 12124 exclusion phecode
587 Kidney replaced by transpant Genitourinary 1.04 0.942 – 1.15 0.44 447 5712 exclusion phecode
588 Disorders resulting from impaired renal function Genitourinary 1.01 0.914 – 1.12 0.841 419 6506 exclusion phecode
588.1 Renal osteodystrophy Genitourinary 1.11 0.93 – 1.32 0.251 146 2027 exclusion phecode
588.2 Secondary hyperparathyroidism (of renal origin) Genitourinary 1.06 0.941 – 1.18 0.357 314 5031 exclusion phecode
589 Abnormal results of function study of kidney Genitourinary 1.06 0.961 – 1.16 0.253 470 6861 exclusion phecode
590 Pyelonephritis Genitourinary 1.07 0.991 – 1.16 0.0855 705 10514 exclusion phecode
591 Urinary tract infection Genitourinary 1.03 0.997 – 1.06 0.0779 5334 23321 exclusion phecode
592 Cystitis and urethritis Genitourinary 1.05 0.992 – 1.1 0.0989 1465 17642 exclusion phecode
592.1 Cystitis Genitourinary 1.05 0.992 – 1.11 0.0964 1382 17003 exclusion phecode
592.11 Acute cystitis Genitourinary 1.01 0.935 – 1.08 0.876 794 11922 exclusion phecode
592.12 Chronic cystitis Genitourinary 0.916 0.753 – 1.12 0.384 111 1680 exclusion phecode
592.13 Chronic interstitial cystitis Genitourinary 1.1 0.971 – 1.26 0.132 245 3200 exclusion phecode
592.2 Urethritis and urethral syndrome Genitourinary 1.09 0.895 – 1.34 0.381 98 1517 exclusion phecode
593 Hematuria Genitourinary 1 0.96 – 1.05 0.924 2439 22952 exclusion phecode
593.1 Gross hematuria Genitourinary 0.984 0.916 – 1.06 0.66 837 10187 exclusion phecode
593.2 Microscopic hematuria Genitourinary 1 0.912 – 1.1 0.973 475 7218 exclusion phecode
594 Urinary calculus Genitourinary 1.04 1.01 – 1.08 0.0197 3826 26385 exclusion phecode
594.1 Calculus of kidney Genitourinary 1.05 1.01 – 1.08 0.0112 3564 26268 exclusion phecode
594.2 Calculus of lower urinary tract Genitourinary 1.03 0.891 – 1.18 0.716 213 2345 exclusion phecode
594.3 Calculus of ureter Genitourinary 1.09 1.01 – 1.18 0.0354 687 9162 exclusion phecode
594.8 Renal colic Genitourinary 1.26 1.07 – 1.47 0.0042 168 2501 exclusion phecode
595 Hydronephrosis Genitourinary 1.1 1.03 – 1.18 0.00407 980 11386 exclusion phecode
596 Other disorders of bladder Genitourinary 1.06 1.01 – 1.11 0.0308 1635 18714 exclusion phecode
596.1 Bladder neck obstruction Genitourinary 1.14 0.995 – 1.31 0.058 221 2582 exclusion phecode
596.5 Functional disorders of bladder Genitourinary 1.06 0.984 – 1.14 0.128 818 11416 exclusion phecode
597 Other disorders of urethra and urinary tract Genitourinary 1.09 1.01 – 1.18 0.0284 710 8069 exclusion phecode
597.1 Urethral stricture (not specified as infectious) Genitourinary 1.13 1.02 – 1.26 0.0174 407 4365 exclusion phecode
597.2 Urinary complications NEC Genitourinary 0.985 0.905 – 1.07 0.72 609 7007 exclusion phecode
597.8 Urethral hypermobility/ISD Genitourinary 1.39 1.13 – 1.71 0.0021 106 1232 exclusion phecode
598 Abnormal findings on examination of urine Genitourinary 1 0.787 – 1.27 0.997 73 878 exclusion phecode
598.4 Other cells and casts in urine Genitourinary 0.951 0.742 – 1.22 0.69 67 772 exclusion phecode
599 Other symptoms/disorders or the urinary system Genitourinary 1.02 0.992 – 1.05 0.181 7817 22603 exclusion phecode
599.1 Urinary obstruction Genitourinary 0.902 0.813 – 1 0.053 377 4734 exclusion phecode
599.2 Retention of urine Genitourinary 1.01 0.965 – 1.05 0.811 2749 20629 exclusion phecode
599.3 Dysuria Genitourinary 1.02 0.973 – 1.06 0.458 2189 20360 exclusion phecode
599.4 Urinary incontinence Genitourinary 1.06 1.01 – 1.1 0.00753 2860 19564 exclusion phecode
599.5 Frequency of urination and polyuria Genitourinary 1.01 0.965 – 1.05 0.802 2732 20915 exclusion phecode
599.6 Oliguria and anuria Genitourinary 0.979 0.866 – 1.11 0.733 277 4213 exclusion phecode
599.7 Urethral discharge Genitourinary 1.02 0.788 – 1.31 0.907 63 792 exclusion phecode
599.8 Other symptoms involving urinary system Genitourinary 1 0.964 – 1.04 0.891 3023 20280 exclusion phecode
599.9 Other abnormality of urination Genitourinary 1.03 0.972 – 1.08 0.345 1431 17911 exclusion phecode
600 Hyperplasia of prostate Genitourinary 0.979 0.929 – 1.03 0.434 2077 7404 exclusion phecode
601 Inflammatory diseases of prostate Genitourinary 0.911 0.828 – 1 0.0584 463 6394 exclusion phecode
601.1 Prostatitis Genitourinary 0.824 0.712 – 0.954 0.00959 196 2990 exclusion phecode
601.11 Acute prostatitis Genitourinary 0.755 0.582 – 0.978 0.0336 55 776 exclusion phecode
601.12 Chronic prostatitis Genitourinary 0.991 0.712 – 1.38 0.955 39 615 exclusion phecode
601.3 Orchitis and epididymitis Genitourinary 0.982 0.839 – 1.15 0.819 168 2528 exclusion phecode
601.4 Balanoposthitis Genitourinary 0.978 0.766 – 1.25 0.856 67 859 exclusion phecode
601.8
Other inflammatory disorders of male genital
Other inflammatory disorders of male genital organs
 Genitourinary 0.934 0.737 – 1.18 0.57 73 1054 exclusion phecode
602 Other disorders of prostate Genitourinary 0.912 0.786 – 1.06 0.227 188 2256 exclusion phecode
602.3 Dysplasia of prostate Genitourinary 0.819 0.607 – 1.1 0.191 47 465 exclusion phecode
603 Other disorders of testis Genitourinary 0.89 0.778 – 1.02 0.0865 235 3082 exclusion phecode
603.1 Hydrocele Genitourinary 0.953 0.803 – 1.13 0.578 145 2004 exclusion phecode
603.2 Spermatocele Genitourinary 0.9 0.727 – 1.11 0.332 95 1117 exclusion phecode
604 Disorders of penis Genitourinary 0.989 0.889 – 1.1 0.845 369 4725 exclusion phecode
604.1 Redundant prepuce and phimosis/BXO Genitourinary 0.866 0.687 – 1.09 0.224 84 1067 exclusion phecode
604.3 Peyronie's disease Genitourinary 1.06 0.891 – 1.27 0.503 132 1446 exclusion phecode
605 Erectile dysfunction [ED] Genitourinary 0.962 0.915 – 1.01 0.132 1958 8826 exclusion phecode
608 Other disorders of male genital organs Genitourinary 1 0.933 – 1.08 0.964 840 9794 exclusion phecode
609 Male infertility and abnormal spermatozoa Genitourinary 0.959 0.844 – 1.09 0.519 254 3019 exclusion phecode
609.1 Infertility, male Genitourinary 0.946 0.816 – 1.1 0.463 189 2180 exclusion phecode
609.11 Azoospermia and oligospermia Genitourinary 0.957 0.748 – 1.22 0.724 69 717 exclusion phecode
609.2 Abnormal spermatozoa Genitourinary 0.96 0.772 – 1.19 0.712 91 1077 exclusion phecode
610 Benign mammary dysplasias Genitourinary 0.967 0.923 – 1.01 0.159 2133 12405 exclusion phecode
610.1 Cystic mastopathy Genitourinary 0.963 0.898 – 1.03 0.292 893 10422 exclusion phecode
610.2 Fibroadenosis of breast Genitourinary 1.07 0.741 – 1.54 0.724 33 450 exclusion phecode
610.4 Benign neoplasm of breast Genitourinary 0.96 0.912 – 1.01 0.127 1666 12304 exclusion phecode
610.8 Other specified benign mammary dysplasias Genitourinary 0.951 0.881 – 1.03 0.205 731 8956 exclusion phecode
611 Abnormal findings on mammogram or breast exam Genitourinary 0.948 0.911 – 0.985 0.00696 3310 13766 exclusion phecode
611.1 Abnormal mammogram Genitourinary 0.94 0.901 – 0.981 0.00459 2724 11942 exclusion phecode
611.11 Mammographic microcalcification Genitourinary 0.884 0.812 – 0.962 0.00432 586 7450 exclusion phecode
611.3 Lump or mass in breast Genitourinary 0.964 0.918 – 1.01 0.142 1888 13706 exclusion phecode
612
Breast conditions, congenital or relating to
Breast conditions, congenital or relating to hormones
 Genitourinary 0.918 0.842 – 1 0.0542 565 7673 exclusion phecode
612.1 Galactorrhea Genitourinary 1.19 0.932 – 1.52 0.162 71 1067 exclusion phecode
612.2 Hypertrophy of breast (Gynecomastia) Genitourinary 0.882 0.797 – 0.977 0.0156 411 5831 exclusion phecode
612.3 Congenital anomalies of breast Genitourinary 0.818 0.613 – 1.09 0.173 49 628 exclusion phecode
613 Other nonmalignant breast conditions Genitourinary 0.958 0.915 – 1 0.0675 2151 15727 exclusion phecode
613.1 Inflammatory disease of breast Genitourinary 0.926 0.825 – 1.04 0.187 317 4165 exclusion phecode
613.5 Mastodynia Genitourinary 0.953 0.886 – 1.03 0.202 800 11343 exclusion phecode
613.7 Other signs and symptoms in breast Genitourinary 0.94 0.851 – 1.04 0.217 441 6166 exclusion phecode
613.8 Other specified disorders of breast Genitourinary 0.985 0.902 – 1.07 0.733 555 6515 exclusion phecode
613.9 Breast disorder NOS Genitourinary 0.983 0.915 – 1.06 0.636 832 9815 exclusion phecode
614 Inflammatory diseases of female pelvic organs Genitourinary 1 0.957 – 1.05 0.88 1992 14301 exclusion phecode
614.1
Pelvic peritoneal adhesions, female
Pelvic peritoneal adhesions, female (postoperative) (postinfection)
 Genitourinary 0.962 0.836 – 1.11 0.594 207 2491 exclusion phecode
614.3 Pelvic inflammatory disease (PID) Genitourinary 1.06 0.93 – 1.21 0.382 254 3549 exclusion phecode
614.31 Acute inflammatory pelvic disease Genitourinary 1.04 0.796 – 1.35 0.793 57 718 exclusion phecode
614.32 Chronic inflammatory pelvic disease Genitourinary 1.12 0.92 – 1.36 0.26 111 1340 exclusion phecode
614.33 Pelvic inflammatory disease, NOS Genitourinary 1.12 0.927 – 1.35 0.244 124 1814 exclusion phecode
614.4 Inflammatory diseases of uterus, except cervix Genitourinary 1.15 0.933 – 1.41 0.194 105 1257 exclusion phecode
614.5
Inflammatory disease of cervix, vagina, and
Inflammatory disease of cervix, vagina, and vulva
 Genitourinary 0.996 0.946 – 1.05 0.886 1662 14240 exclusion phecode
614.51 Cervicitis and endocervicitis Genitourinary 0.953 0.806 – 1.13 0.573 145 1981 exclusion phecode
614.52 Vaginitis and vulvovaginitis Genitourinary 1 0.948 – 1.06 0.915 1396 13820 exclusion phecode
614.53 Cyst or abscess of Bartholin's gland Genitourinary 1.04 0.808 – 1.34 0.754 64 960 exclusion phecode
614.54 Abscess or ulceration of vulva Genitourinary 0.91 0.751 – 1.1 0.333 118 1638 exclusion phecode
615 Endometriosis Genitourinary 1.03 0.963 – 1.1 0.387 923 10685 exclusion phecode
618 Genital prolapse Genitourinary 1.05 0.993 – 1.12 0.0843 1254 12186 exclusion phecode
618.1 Prolapse of vaginal walls Genitourinary 1.02 0.955 – 1.1 0.513 904 9001 exclusion phecode
618.2 Uterine/Uterovaginal prolapse Genitourinary 1.01 0.904 – 1.13 0.85 345 3609 exclusion phecode
618.5 Prolapse of vaginal vault after hysterectomy Genitourinary 1.18 1.03 – 1.36 0.0156 236 2103 exclusion phecode
618.6 Vaginal enterocele, congenital or acquired Genitourinary 1.3 1.14 – 1.49 8.91e-05 241 2926 exclusion phecode
619 Noninflammatory female genital disorders Genitourinary 0.969 0.932 – 1.01 0.102 3398 13552 exclusion phecode
619.1
Noninflammatory disorders of ovary, fallopian
Noninflammatory disorders of ovary, fallopian tube, and broad ligament
 Genitourinary 0.984 0.913 – 1.06 0.671 761 8969 exclusion phecode
619.2 Disorders of uterus, NEC Genitourinary 1.04 0.936 – 1.16 0.447 351 4287 exclusion phecode
619.3 Noninflammatory disorders of cervix Genitourinary 0.97 0.86 – 1.1 0.627 283 3573 exclusion phecode
619.4 Noninflammatory disorders of vagina Genitourinary 0.971 0.918 – 1.03 0.293 1419 13353 exclusion phecode
619.5 Noninflammatory disorders of vulva and perineum Genitourinary 0.977 0.9 – 1.06 0.579 621 8378 exclusion phecode
620 Dysplasia of female genital organs Genitourinary 1 0.873 – 1.15 0.977 220 2761 exclusion phecode
620.1 Dysplasia of cervix Genitourinary 1.01 0.82 – 1.24 0.953 101 1259 exclusion phecode
621 Endometrial hyperplasia Genitourinary 0.91 0.795 – 1.04 0.166 227 3030 exclusion phecode
622 Polyp of female genital organs Genitourinary 0.96 0.892 – 1.03 0.275 780 9897 exclusion phecode
622.1 Polyp of corpus uteri Genitourinary 0.96 0.884 – 1.04 0.338 609 7794 exclusion phecode
622.2 Mucous polyp of cervix Genitourinary 0.886 0.774 – 1.02 0.0826 222 3027 exclusion phecode
623 Hypertrophy of female genital organs Genitourinary 0.939 0.851 – 1.04 0.21 436 5685 exclusion phecode
624 Symptoms involving female genital tract Genitourinary 0.974 0.904 – 1.05 0.485 758 9455 exclusion phecode
624.1 Dystrophy of female genital tract Genitourinary 0.908 0.747 – 1.1 0.332 109 1518 exclusion phecode
624.2 Atrophy of female genital tract Genitourinary 0.887 0.629 – 1.25 0.496 35 436 exclusion phecode
624.9 stress incontinence, female Genitourinary 1.02 0.96 – 1.09 0.458 1012 11239 exclusion phecode
625
Pain and other symptoms associated with female
Pain and other symptoms associated with female genital organs
 Genitourinary 0.988 0.95 – 1.03 0.547 3169 12897 exclusion phecode
625.1 Dyspareunia Genitourinary 0.999 0.925 – 1.08 0.982 723 9338 exclusion phecode
626
Disorders of menstruation and other abnormal
Disorders of menstruation and other abnormal bleeding from female genital tract
 Genitourinary 0.976 0.938 – 1.01 0.221 3481 11860 exclusion phecode
626.1 Irregular menstrual cycle/bleeding Genitourinary 0.981 0.937 – 1.03 0.409 2401 11131 exclusion phecode
626.11 Absent or infrequent menstruation Genitourinary 0.975 0.895 – 1.06 0.567 589 6810 exclusion phecode
626.12 Excessive or frequent menstruation Genitourinary 1.01 0.945 – 1.07 0.831 1119 9297 exclusion phecode
626.13 Irregular menstrual cycle Genitourinary 1.02 0.954 – 1.09 0.577 1007 9497 exclusion phecode
626.14 Irregular menstrual bleeding Genitourinary 0.965 0.88 – 1.06 0.437 512 7064 exclusion phecode
626.15 Infertility, female, associated with anovulation Genitourinary 0.992 0.865 – 1.14 0.903 235 3083 exclusion phecode
626.2 Dysmenorrhea Genitourinary 1.02 0.947 – 1.1 0.603 793 7802 exclusion phecode
626.4 Premenstrual tension syndromes Genitourinary 0.913 0.776 – 1.07 0.272 158 2602 exclusion phecode
626.8 Infertility, female Genitourinary 0.921 0.842 – 1.01 0.0764 534 5438 exclusion phecode
627 Menopausal and postmenopausal disorders Genitourinary 0.963 0.92 – 1.01 0.107 2307 10932 exclusion phecode
627.1 Postmenopausal bleeding Genitourinary 0.94 0.858 – 1.03 0.189 504 7446 exclusion phecode
627.2 Symptomatic menopause Genitourinary 0.967 0.915 – 1.02 0.24 1482 10243 exclusion phecode
627.21 Symptomatic artificial menopause Genitourinary 0.874 0.699 – 1.09 0.239 83 1145 exclusion phecode
627.22
Need for Hormone replacement therapy
Need for Hormone replacement therapy (postmenopausal)
 Genitourinary 1.03 0.878 – 1.21 0.701 162 2500 exclusion phecode
627.3 Postmenopausal atrophic vaginitis Genitourinary 0.95 0.866 – 1.04 0.275 492 6825 exclusion phecode
627.4 Premenopausal menorrhagia Genitourinary 1.1 0.941 – 1.29 0.231 180 2713 exclusion phecode
627.5 Premature menopause and other ovarian failure Genitourinary 0.87 0.747 – 1.01 0.0718 179 2358 exclusion phecode
628 Ovarian cyst Genitourinary 1.01 0.944 – 1.07 0.845 1078 10602 exclusion phecode
634 Miscarriage; stillbirth Pregnancy Complications 0.908 0.83 – 0.992 0.0333 531 5934 exclusion phecode
634.1 Missed abortion/Hydatidiform mole Pregnancy Complications 0.857 0.729 – 1.01 0.0602 172 2032 exclusion phecode
634.3 Ectopic pregnancy Pregnancy Complications 0.95 0.764 – 1.18 0.646 84 883 exclusion phecode
635
Hemorrhage during pregnancy; childbirth and
Hemorrhage during pregnancy; childbirth and postpartum
 Pregnancy Complications 0.916 0.827 – 1.01 0.0937 408 4121 exclusion phecode
635.2
Antepartum hemorrhage, abruptio placentae, and
Antepartum hemorrhage, abruptio placentae, and placenta previa
 Pregnancy Complications 0.891 0.785 – 1.01 0.074 262 2799 exclusion phecode
635.3 Placenta previa and abruptio placenta Pregnancy Complications 0.94 0.818 – 1.08 0.382 218 2265 exclusion phecode
636
Early or threatened labor; hemorrhage in early
Early or threatened labor; hemorrhage in early pregnancy
 Pregnancy Complications 0.95 0.879 – 1.03 0.196 723 5949 exclusion phecode
636.1 Threatened premature labor Pregnancy Complications 0.966 0.848 – 1.1 0.606 249 2948 exclusion phecode
636.2 Early onset of delivery Pregnancy Complications 0.95 0.823 – 1.1 0.484 194 2194 exclusion phecode
636.3 Hemorrhage in early pregnancy Pregnancy Complications 0.92 0.813 – 1.04 0.187 276 3360 exclusion phecode
636.8 Cervical incompetence Pregnancy Complications 1.18 0.885 – 1.58 0.257 50 597 exclusion phecode
637
Short gestation; low birth weight; and fetal
Short gestation; low birth weight; and fetal growth retardation
 Pregnancy Complications 1.24 0.921 – 1.67 0.156 39 627 exclusion phecode
642
Hypertension complicating pregnancy
Hypertension complicating pregnancy, childbirth, and the puerperium
 Pregnancy Complications 0.923 0.83 – 1.03 0.141 371 4382 exclusion phecode
642.1 Preeclampsia and eclampsia Pregnancy Complications 0.883 0.763 – 1.02 0.0937 191 2298 exclusion phecode
643 Excessive vomiting in pregnancy Pregnancy Complications 1.05 0.896 – 1.23 0.535 164 1955 exclusion phecode
643.1 Hyperemesis gravidarum Pregnancy Complications 1.03 0.808 – 1.31 0.819 74 907 exclusion phecode
644 Anemia during pregnancy Pregnancy Complications 1.16 0.99 – 1.36 0.0673 160 1747 exclusion phecode
646 Other complications of pregnancy NEC Pregnancy Complications 1.03 0.943 – 1.12 0.535 590 5080 exclusion phecode
647
Infectious and parasitic complications
Infectious and parasitic complications affecting pregnancy
 Pregnancy Complications 1.01 0.854 – 1.2 0.877 147 1581 exclusion phecode
647.1
Infections of genitourinary tract during
Infections of genitourinary tract during pregnancy
 Pregnancy Complications 1.13 0.956 – 1.33 0.152 152 1751 exclusion phecode
647.3 Major puerperal infection Pregnancy Complications 0.903 0.674 – 1.21 0.494 51 514 exclusion phecode
649
Other conditions or status of the mother
Other conditions or status of the mother complicating pregnancy, childbirth, or the puerperium
 Pregnancy Complications 1.02 0.949 – 1.1 0.593 881 6088 exclusion phecode
649.1
Diabetes or abnormal glucose tolerance
Diabetes or abnormal glucose tolerance complicating pregnancy
 Pregnancy Complications 1.07 0.963 – 1.19 0.204 383 4086 exclusion phecode
653
Problems associated with amniotic cavity and
Problems associated with amniotic cavity and membranes
 Pregnancy Complications 0.993 0.897 – 1.1 0.897 407 4198 exclusion phecode
654.1
Abnormality of organs and soft tissues of
Abnormality of organs and soft tissues of pelvis complicating pregnancy, childbirth, or the puerperium
 Pregnancy Complications 1.05 0.886 – 1.24 0.594 149 1574 exclusion phecode
654.2 Rhesus isoimmunization in pregnancy Pregnancy Complications 0.997 0.841 – 1.18 0.973 140 1540 exclusion phecode
655
Known or suspected fetal abnormality affecting
Known or suspected fetal abnormality affecting management of mother
 Pregnancy Complications 0.978 0.917 – 1.04 0.506 1096 7473 exclusion phecode
655.1 Abnormality in fetal heart rate or rhythm Pregnancy Complications 0.923 0.836 – 1.02 0.111 447 4317 exclusion phecode
656 Other perinatal conditions of fetus or newborn Pregnancy Complications 0.999 0.918 – 1.09 0.973 616 5316 exclusion phecode
656.2 Respiratory conditions of fetus and newborn Pregnancy Complications 1.15 0.765 – 1.74 0.495 20 442 exclusion phecode
669 Complications of labor and delivery NEC Pregnancy Complications 0.977 0.899 – 1.06 0.573 630 5203 exclusion phecode
671
Venous/cerebrovascular complications embolism
Venous/cerebrovascular complications embolism in pregnancy and the puerperium
 Pregnancy Complications 0.992 0.833 – 1.18 0.933 141 1761 exclusion phecode
674 Other complications of the puerperium NEC Pregnancy Complications 1.19 0.972 – 1.46 0.0914 106 1238 exclusion phecode
676
Other disorders of the breast associated with
Other disorders of the breast associated with childbirth and disorders of lactation
 Pregnancy Complications 0.978 0.818 – 1.17 0.807 127 1409 exclusion phecode
681 Superficial cellulitis and abscess Dermatologic 0.995 0.958 – 1.03 0.8 3039 27523 exclusion phecode
681.1 Cellulitis and abscess of fingers/toes Dermatologic 0.982 0.894 – 1.08 0.697 471 7931 exclusion phecode
681.2 Cellulitis and abscess of face/neck Dermatologic 0.93 0.847 – 1.02 0.13 467 6938 exclusion phecode
681.3 Cellulitis and abscess of arm/hand Dermatologic 0.987 0.921 – 1.06 0.712 869 13958 exclusion phecode
681.5 Cellulitis and abscess of leg, except foot Dermatologic 0.969 0.906 – 1.04 0.35 934 14615 exclusion phecode
681.6 Cellulitis and abscess of foot, toe Dermatologic 1.03 0.958 – 1.11 0.398 739 11711 exclusion phecode
681.7 Cellulitis and abscess of trunk Dermatologic 1.07 0.99 – 1.16 0.0873 714 10877 exclusion phecode
686
Other local infections of skin and subcutaneous
Other local infections of skin and subcutaneous tissue
 Dermatologic 1.03 0.964 – 1.1 0.398 1037 15172 exclusion phecode
686.1 Carbuncle and furuncle Dermatologic 0.948 0.829 – 1.08 0.434 240 3915 exclusion phecode
686.2 Impetigo Dermatologic 0.97 0.838 – 1.12 0.677 189 2934 exclusion phecode
686.3 Pilonidal cyst Dermatologic 0.931 0.752 – 1.15 0.508 89 1152 exclusion phecode
686.4 Pyogenic granuloma Dermatologic 0.965 0.766 – 1.22 0.763 77 1117 exclusion phecode
686.5 Pyoderma Dermatologic 1.05 0.737 – 1.48 0.803 33 451 exclusion phecode
687 Symptoms affecting skin Dermatologic 1 0.929 – 1.08 0.967 736 11828 exclusion phecode
687.1 Rash and other nonspecific skin eruption Dermatologic 0.964 0.929 – 1 0.0529 3220 25645 exclusion phecode
687.3 Changes in skin texture Dermatologic 0.94 0.802 – 1.1 0.444 162 2893 exclusion phecode
687.4 Disturbance of skin sensation Dermatologic 1.01 0.97 – 1.05 0.66 2921 25275 exclusion phecode
689 Disorder of skin and subcutaneous tissue NOS Dermatologic 0.96 0.93 – 0.991 0.0106 4824 26709 exclusion phecode
690 Erythematosquamous dermatosis Dermatologic 0.943 0.903 – 0.984 0.0066 2447 22174 exclusion phecode
690.1 Seborrheic dermatitis Dermatologic 0.943 0.903 – 0.984 0.00671 2443 22151 exclusion phecode
691 Congenital anomalies of skin Dermatologic 0.989 0.87 – 1.13 0.868 253 3824 exclusion phecode
691.3 Congenital pigmentary anomalies of skin Dermatologic 0.813 0.565 – 1.17 0.267 31 461 exclusion phecode
694 Dyschromia and Vitiligo Dermatologic 0.97 0.908 – 1.04 0.367 965 12673 exclusion phecode
694.1 Vitiligo Dermatologic 0.959 0.763 – 1.21 0.722 80 922 exclusion phecode
694.2 Other dyschromia Dermatologic 0.959 0.894 – 1.03 0.248 867 11436 exclusion phecode
694.3 Vascular disorders of skin Dermatologic 1.51 1.08 – 2.1 0.0149 32 564 exclusion phecode
695 Erythematous conditions Dermatologic 0.967 0.922 – 1.01 0.169 1922 21553 exclusion phecode
695.1 Toxic erythema Dermatologic 1.03 0.73 – 1.46 0.858 39 495 exclusion phecode
695.2 Bullous dermatoses Dermatologic 1.13 0.795 – 1.59 0.506 37 534 exclusion phecode
695.3 Rosacea Dermatologic 0.91 0.848 – 0.977 0.0089 846 12423 exclusion phecode
695.4 Lupus (localized and systemic) Dermatologic 1.02 0.919 – 1.14 0.668 363 4872 exclusion phecode
695.41 Cutaneous lupus erythematosus Dermatologic 0.947 0.797 – 1.12 0.532 139 1787 exclusion phecode
695.42 Systemic lupus erythematosus Dermatologic 1.05 0.938 – 1.17 0.404 344 4611 exclusion phecode
695.7 Prurigo and Lichen Dermatologic 0.981 0.864 – 1.11 0.771 261 4183 exclusion phecode
695.8 Other specified erythematous conditions Dermatologic 1 0.889 – 1.12 0.999 295 5602 exclusion phecode
695.81 Erythema nodosum Dermatologic 0.828 0.586 – 1.17 0.282 31 425 exclusion phecode
695.9 Unspecified erythematous condition Dermatologic 1.07 0.948 – 1.21 0.275 284 4692 exclusion phecode
696 Psoriasis and related disorders Dermatologic 0.982 0.908 – 1.06 0.646 697 9819 exclusion phecode
696.3 Pityriasis Dermatologic 0.831 0.623 – 1.11 0.209 54 685 exclusion phecode
696.4 Psoriasis Dermatologic 0.996 0.918 – 1.08 0.916 643 9126 exclusion phecode
696.41 Psoriasis vulgaris Dermatologic 1.01 0.925 – 1.1 0.863 588 8340 exclusion phecode
696.42 Psoriatic arthropathy Dermatologic 0.937 0.777 – 1.13 0.495 123 1941 exclusion phecode
697 Sarcoidosis Dermatologic 0.977 0.822 – 1.16 0.793 139 2306 exclusion phecode
698 Pruritus and related conditions Dermatologic 1.02 0.956 – 1.09 0.558 1000 15004 exclusion phecode
700 Corns and callosities Dermatologic 0.995 0.908 – 1.09 0.914 514 7431 exclusion phecode
701
Other hypertrophic and atrophic conditions of
Other hypertrophic and atrophic conditions of skin
 Dermatologic 0.986 0.953 – 1.02 0.425 3899 27182 exclusion phecode
701.1 Keratoderma, acquired Dermatologic 0.925 0.808 – 1.06 0.263 227 3777 exclusion phecode
701.2 Scar conditions and fibrosis of skin Dermatologic 0.988 0.933 – 1.05 0.689 1305 15231 exclusion phecode
701.3 Circumscribed scleroderma Dermatologic 0.935 0.832 – 1.05 0.261 318 3954 exclusion phecode
701.4 Keloid scar Dermatologic 0.981 0.876 – 1.1 0.739 324 4172 exclusion phecode
701.5 Abnormal granulation tissue Dermatologic 1.05 0.9 – 1.21 0.562 193 2849 exclusion phecode
702
Degenerative skin conditions and other
Degenerative skin conditions and other dermatoses
 Dermatologic 0.947 0.913 – 0.983 0.00449 3429 20886 exclusion phecode
702.1 Actinic keratosis Dermatologic 0.962 0.917 – 1.01 0.104 2037 17882 exclusion phecode
702.2 Seborrheic keratosis Dermatologic 0.93 0.892 – 0.97 0.000633 2613 21468 exclusion phecode
702.4 Degenerative skin disorders Dermatologic 1.08 0.787 – 1.48 0.632 38 613 exclusion phecode
703 Diseases of nail, NOS Dermatologic 1 0.921 – 1.09 0.976 590 9935 exclusion phecode
703.1 Ingrowing nail Dermatologic 1.04 0.926 – 1.17 0.514 307 5909 exclusion phecode
704 Diseases of hair and hair follicles Dermatologic 0.987 0.935 – 1.04 0.62 1498 20799 exclusion phecode
704.1 Alopecia Dermatologic 0.999 0.924 – 1.08 0.971 706 9931 exclusion phecode
704.11 Alopecia Areata Dermatologic 0.853 0.625 – 1.16 0.314 40 564 exclusion phecode
704.12 Telogen effluvium Dermatologic 0.768 0.517 – 1.14 0.192 23 480 exclusion phecode
704.2 Hirsutism Dermatologic 1.06 0.899 – 1.25 0.497 153 2202 exclusion phecode
704.8
Other specified diseases of hair and hair
Other specified diseases of hair and hair follicles
 Dermatologic 0.99 0.92 – 1.06 0.786 795 11856 exclusion phecode
705 Disorders of sweat glands Dermatologic 0.99 0.877 – 1.12 0.876 269 4382 exclusion phecode
705.1 Dyshidrosis Dermatologic 1.09 0.86 – 1.37 0.491 72 1081 exclusion phecode
705.3 Hidradenitis Dermatologic 0.92 0.763 – 1.11 0.381 114 1825 exclusion phecode
705.8 Hyperhidrosis Dermatologic 0.973 0.881 – 1.07 0.588 423 7768 exclusion phecode
706 Diseases of sebaceous glands Dermatologic 0.943 0.907 – 0.98 0.0028 2953 28234 exclusion phecode
706.1 Acne Dermatologic 0.93 0.879 – 0.984 0.0112 1362 16562 exclusion phecode
706.2 Sebaceous cyst Dermatologic 0.949 0.897 – 1 0.0725 1330 18685 exclusion phecode
706.3 Seborrhea Dermatologic 0.858 0.547 – 1.35 0.505 17 408 exclusion phecode
706.8 Other specified diseases of sebaceous glands Dermatologic 0.927 0.857 – 1 0.0554 684 10397 exclusion phecode
707 Chronic ulcer of skin Dermatologic 1.04 0.979 – 1.1 0.225 1306 17885 exclusion phecode
707.1 Decubitus ulcer Dermatologic 1.06 0.951 – 1.18 0.29 347 5319 exclusion phecode
707.2 Chronic ulcer of leg or foot Dermatologic 1.08 0.979 – 1.19 0.126 447 6465 exclusion phecode
707.3 Chronic ulcer of unspecified site Dermatologic 1.01 0.934 – 1.09 0.857 747 10758 exclusion phecode
709 Diffuse diseases of connective tissue Dermatologic 0.994 0.919 – 1.08 0.884 670 10361 exclusion phecode
709.2 Sicca syndrome Dermatologic 0.998 0.873 – 1.14 0.978 228 3557 exclusion phecode
709.3 Systemic sclerosis Dermatologic 0.837 0.69 – 1.02 0.0721 107 1574 exclusion phecode
709.5 Dermatomyositis Dermatologic 1.03 0.741 – 1.42 0.878 41 643 exclusion phecode
709.6
Other specified diffuse diseases of connective
Other specified diffuse diseases of connective tissue
 Dermatologic 1.32 0.964 – 1.79 0.0835 39 672 exclusion phecode
709.7 Unspecified diffuse connective tissue disease Dermatologic 1.04 0.943 – 1.16 0.408 399 6533 exclusion phecode
710
Osteomyelitis, periostitis, and other
Osteomyelitis, periostitis, and other infections involving bone
 Musculoskeletal 1.05 0.965 – 1.13 0.273 644 8720 exclusion phecode
710.1 Osteomyelitis Musculoskeletal 1.04 0.959 – 1.13 0.33 615 8373 exclusion phecode
710.11 Acute osteomyelitis Musculoskeletal 1.14 1.01 – 1.29 0.0353 272 4038 exclusion phecode
710.12 Chronic osteomyelitis Musculoskeletal 1.1 0.969 – 1.25 0.14 252 3626 exclusion phecode
710.19 Unspecified osteomyelitis Musculoskeletal 1.05 0.962 – 1.14 0.288 590 7997 exclusion phecode
711 Arthropathy associated with infections Musculoskeletal 1.05 0.905 – 1.21 0.532 192 2991 exclusion phecode
711.1 Pyogenic arthritis Musculoskeletal 1.12 0.942 – 1.33 0.198 136 2094 exclusion phecode
712 Infective connective tissue disorders Musculoskeletal 0.939 0.737 – 1.2 0.608 70 1277 exclusion phecode
713
Arthropathy associated with other disorders
Arthropathy associated with other disorders classified elsewhere
 Musculoskeletal 1.02 0.853 – 1.21 0.849 125 2108 exclusion phecode
713.5
Arthropathy associated with neurological
Arthropathy associated with neurological disorders
 Musculoskeletal 1.04 0.825 – 1.3 0.758 73 1191 exclusion phecode
714
Rheumatoid arthritis and other inflammatory
Rheumatoid arthritis and other inflammatory polyarthropathies
 Musculoskeletal 1.03 0.965 – 1.1 0.386 1046 13305 exclusion phecode
714.1 Rheumatoid arthritis Musculoskeletal 1.04 0.97 – 1.12 0.265 869 11062 exclusion phecode
714.2 Juvenile rheumatoid arthritis Musculoskeletal 0.76 0.559 – 1.03 0.0792 41 603 exclusion phecode
715 Other inflammatory spondylopathies Musculoskeletal 1.05 0.958 – 1.15 0.296 488 8689 exclusion phecode
715.1 Sacroiliitis NEC Musculoskeletal 1.19 0.989 – 1.44 0.0655 116 1936 exclusion phecode
715.2 Ankylosing spondylitis Musculoskeletal 1.03 0.854 – 1.25 0.745 117 1592 exclusion phecode
716 Other arthropathies Musculoskeletal 1.04 1.01 – 1.07 0.00664 7055 23284 exclusion phecode
716.1 Unspecified polyarthropathy or polyarthritis Musculoskeletal 1.09 0.867 – 1.36 0.468 76 1398 exclusion phecode
716.2 Unspecified monoarthritis Musculoskeletal 0.86 0.668 – 1.11 0.245 59 943 exclusion phecode
716.9 Arthropathy NOS Musculoskeletal 1.04 1.01 – 1.07 0.00902 7020 23274 exclusion phecode
717 Polymyalgia Rheumatica Musculoskeletal 1.05 0.876 – 1.25 0.613 136 1616 exclusion phecode
720 Spinal stenosis Musculoskeletal 1.06 1.01 – 1.11 0.0193 1846 20153 exclusion phecode
720.1 Spinal stenosis of lumbar region Musculoskeletal 1.02 0.967 – 1.08 0.419 1315 16580 exclusion phecode
721 Spondylosis and allied disorders Musculoskeletal 1.05 1.01 – 1.1 0.0177 2393 23209 exclusion phecode
721.1 Spondylosis without myelopathy Musculoskeletal 1.06 1.01 – 1.11 0.0101 2202 22799 exclusion phecode
721.2 Spondylosis with myelopathy Musculoskeletal 1.07 0.968 – 1.19 0.177 397 6089 exclusion phecode
721.8 Other allied disorders of spine Musculoskeletal 0.953 0.777 – 1.17 0.639 100 1777 exclusion phecode
722 Intervertebral disc disorders Musculoskeletal 1.03 0.993 – 1.07 0.108 2998 24866 exclusion phecode
722.1 Displacement of intervertebral disc Musculoskeletal 1.04 0.99 – 1.09 0.12 1673 22588 exclusion phecode
722.3 Schmorl's nodes Musculoskeletal 0.871 0.652 – 1.16 0.35 48 905 exclusion phecode
722.6 Degeneration of intervertebral disc Musculoskeletal 1.05 1 – 1.11 0.034 1800 21883 exclusion phecode
722.7 Intervertebral disc disorder with myelopathy Musculoskeletal 0.998 0.874 – 1.14 0.973 243 3650 exclusion phecode
722.8 Postlaminectomy syndrome Musculoskeletal 1.11 0.945 – 1.3 0.207 167 2800 exclusion phecode
722.9 Other and unspecified disc disorder Musculoskeletal 1 0.938 – 1.08 0.898 886 13701 exclusion phecode
723 Other disorders of cervical region Musculoskeletal 1.04 0.939 – 1.15 0.47 402 6862 exclusion phecode
723.1 Torticollis Musculoskeletal 0.924 0.766 – 1.11 0.407 115 1832 exclusion phecode
724 Other and unspecified disorders of back Musculoskeletal 1.03 0.979 – 1.08 0.273 1820 23197 exclusion phecode
724.1 Disorders of sacrum Musculoskeletal 1.02 0.955 – 1.09 0.549 936 15873 exclusion phecode
724.2 Disorders of coccyx Musculoskeletal 0.983 0.837 – 1.16 0.838 159 3056 exclusion phecode
724.8 Other symptoms referable to back Musculoskeletal 1.07 0.964 – 1.18 0.207 398 6751 exclusion phecode
724.9 Other unspecified back disorders Musculoskeletal 1.05 0.973 – 1.14 0.204 696 10084 exclusion phecode
726 Peripheral enthesopathies and allied syndromes Musculoskeletal 0.963 0.933 – 0.994 0.0199 4804 22999 exclusion phecode
726.1 Enthesopathy Musculoskeletal 0.988 0.953 – 1.02 0.501 3629 22947 exclusion phecode
726.2 Synoviopathy Musculoskeletal 1.1 0.998 – 1.21 0.0547 454 7359 exclusion phecode
726.3 Bursitis Musculoskeletal 0.994 0.924 – 1.07 0.868 793 12505 exclusion phecode
726.4 Calcaneal spur; Exostosis NOS Musculoskeletal 0.985 0.903 – 1.08 0.741 555 8586 exclusion phecode
727 Other disorders of synovium, tendon, and bursa Musculoskeletal 0.99 0.956 – 1.03 0.599 3630 22944 exclusion phecode
727.1 Synovitis and tenosynovitis Musculoskeletal 0.992 0.94 – 1.05 0.783 1450 19018 exclusion phecode
727.2 Bursitis disorders Musculoskeletal 0.913 0.785 – 1.06 0.235 183 3063 exclusion phecode
727.4 Ganglion and cyst of synovium, tendon, and bursa Musculoskeletal 0.953 0.881 – 1.03 0.233 682 10241 exclusion phecode
727.5 Rupture of synovium Musculoskeletal 0.958 0.83 – 1.11 0.555 205 3512 exclusion phecode
727.6 Rupture of tendon, nontraumatic Musculoskeletal 1 0.941 – 1.07 0.965 1092 16132 exclusion phecode
727.7 Contracture of tendon (sheath) Musculoskeletal 0.974 0.858 – 1.11 0.686 265 4518 exclusion phecode
727.8 Plica syndrome Musculoskeletal 0.914 0.745 – 1.12 0.391 99 1017 exclusion phecode
728 Disorders of muscle, ligament, and fascia Musculoskeletal 0.995 0.951 – 1.04 0.838 2053 22379 exclusion phecode
728.1 Muscular calcification and ossification Musculoskeletal 1.48 1.08 – 2.02 0.0135 40 625 exclusion phecode
728.2 Laxity of ligament or hypermobility syndrome Musculoskeletal 0.975 0.823 – 1.16 0.774 148 2282 exclusion phecode
728.7 Fasciitis Musculoskeletal 0.969 0.913 – 1.03 0.302 1188 17599 exclusion phecode
728.71
Contracture of palmar fascia [Dupuytren's
Contracture of palmar fascia [Dupuytren's disease]
 Musculoskeletal 0.983 0.854 – 1.13 0.81 209 2916 exclusion phecode
729 Other disorders of soft tissues Musculoskeletal 1.03 0.982 – 1.09 0.197 1567 20656 exclusion phecode
729.1 Rheumatism, unspecified and fibrositis Musculoskeletal 1.24 0.824 – 1.87 0.302 22 529 exclusion phecode
729.3 Panniculitis Musculoskeletal 0.788 0.582 – 1.07 0.123 42 874 exclusion phecode
729.7 Nontraumatic compartment syndrome Musculoskeletal 1.02 0.745 – 1.39 0.914 36 492 exclusion phecode
731
Osteitis deformans and osteopathies associated
Osteitis deformans and osteopathies associated with other disorders classified elsewhere
 Musculoskeletal 0.848 0.693 – 1.04 0.112 96 1350 exclusion phecode
732 Osteochondropathies Musculoskeletal 0.883 0.773 – 1.01 0.0661 231 2765 exclusion phecode
732.1 Juvenile osteochondrosis Musculoskeletal 0.843 0.699 – 1.02 0.0721 115 1468 exclusion phecode
732.7 Osteochondritis dissecans Musculoskeletal 0.924 0.714 – 1.2 0.55 61 682 exclusion phecode
733 Other disorders of bone and cartilage Musculoskeletal 0.93 0.889 – 0.973 0.00178 2234 19146 exclusion phecode
733.2 Cyst of bone Musculoskeletal 0.859 0.703 – 1.05 0.141 99 1364 exclusion phecode
733.4 Aseptic necrosis of bone Musculoskeletal 0.989 0.877 – 1.12 0.854 300 3611 exclusion phecode
733.6 Costochondritis Musculoskeletal 0.917 0.77 – 1.09 0.328 134 2626 exclusion phecode
733.8 Malunion and nonunion of fracture Musculoskeletal 1.04 0.947 – 1.15 0.395 479 5946 exclusion phecode
733.9 Chondromalacia Musculoskeletal 1.01 0.769 – 1.33 0.93 59 760 exclusion phecode
735 Acquired foot deformities Musculoskeletal 1 0.95 – 1.06 0.968 1550 20497 exclusion phecode
735.1 Flat foot Musculoskeletal 0.985 0.867 – 1.12 0.822 257 4128 exclusion phecode
735.2 Acquired toe deformities Musculoskeletal 1.05 0.957 – 1.14 0.32 554 7994 exclusion phecode
735.21 Hammer toe (acquired) Musculoskeletal 1.04 0.929 – 1.16 0.5 326 4940 exclusion phecode
735.23 Hallux rigidus Musculoskeletal 1.03 0.885 – 1.2 0.712 181 2633 exclusion phecode
735.3 Hallux valgus (Bunion) Musculoskeletal 1.01 0.937 – 1.1 0.734 669 9823 exclusion phecode
736 Other acquired deformities of limbs Musculoskeletal 1.03 0.973 – 1.09 0.31 1336 18464 exclusion phecode
736.1 Acquired deformities of forearm Musculoskeletal 1.14 0.867 – 1.49 0.352 52 722 exclusion phecode
736.2 Acquired deformities of finger Musculoskeletal 1.1 0.913 – 1.33 0.314 107 1506 exclusion phecode
736.3 Acquired deformities of hip Musculoskeletal 1.25 0.915 – 1.7 0.163 38 456 exclusion phecode
736.4 Genu valgum or varum (acquired) Musculoskeletal 0.852 0.732 – 0.992 0.0395 167 2266 exclusion phecode
736.5 Acquired deformities of knee Musculoskeletal 0.841 0.697 – 1.02 0.0715 116 1701 exclusion phecode
736.6 Unequal leg length (acquired) Musculoskeletal 0.999 0.849 – 1.18 0.992 159 2364 exclusion phecode
737 Curvature of spine Musculoskeletal 0.96 0.894 – 1.03 0.259 827 11046 exclusion phecode
737.1 Kyphosis (acquired) Musculoskeletal 1.04 0.914 – 1.19 0.532 236 3348 exclusion phecode
737.2 Lordosis (acquired) Musculoskeletal 0.928 0.679 – 1.27 0.637 42 497 exclusion phecode
737.3 Kyphoscoliosis and scoliosis Musculoskeletal 0.946 0.873 – 1.03 0.178 646 8567 exclusion phecode
738 Other acquired musculoskeletal deformity Musculoskeletal 0.963 0.91 – 1.02 0.189 1359 16881 exclusion phecode
738.4 Acquired spondylolisthesis Musculoskeletal 1.02 0.934 – 1.12 0.634 517 7122 exclusion phecode
739 Contracture of joint Musculoskeletal 0.991 0.885 – 1.11 0.877 327 4304 exclusion phecode
740 Osteoarthrosis Musculoskeletal 1.03 1 – 1.06 0.0205 8512 22851 exclusion phecode
740.1 Osteoarthritis; localized Musculoskeletal 1.01 0.973 – 1.05 0.585 3280 20372 exclusion phecode
740.11 Osteoarthrosis, localized, primary Musculoskeletal 0.995 0.956 – 1.04 0.817 2839 19316 exclusion phecode
740.12 Osteoarthrosis, localized, secondary Musculoskeletal 1.06 0.949 – 1.18 0.316 361 5297 exclusion phecode
740.2 Osteoarthrosis, generalized Musculoskeletal 1 0.923 – 1.09 0.957 614 8934 exclusion phecode
740.3
Osteoarthrosis involving more than one site
Osteoarthrosis involving more than one site, but not specified as generalized
 Musculoskeletal 0.966 0.817 – 1.14 0.686 146 2674 exclusion phecode
740.9 Osteoarthrosis NOS Musculoskeletal 1.03 1 – 1.06 0.035 8114 22733 exclusion phecode
741 Symptoms and disorders of the joints Musculoskeletal 1 0.971 – 1.04 0.865 4378 25946 exclusion phecode
741.1 Ankylosis of joint Musculoskeletal 0.996 0.835 – 1.19 0.964 139 1765 exclusion phecode
741.2 Stiffness of joint Musculoskeletal 1.06 0.978 – 1.15 0.159 654 8967 exclusion phecode
741.3 Difficulty in walking Musculoskeletal 1.01 0.95 – 1.07 0.763 1134 16274 exclusion phecode
741.4 Joint effusions Musculoskeletal 0.962 0.906 – 1.02 0.207 1170 17473 exclusion phecode
741.5 Hemarthrosis Musculoskeletal 1.15 0.835 – 1.59 0.388 35 666 exclusion phecode
741.6 Villonodular synovitis Musculoskeletal 1.23 0.87 – 1.75 0.239 33 482 exclusion phecode
742 Derangement of joint, non-traumatic Musculoskeletal 1 0.957 – 1.05 0.978 2231 24510 exclusion phecode
742.1 Loose body in joint Musculoskeletal 0.924 0.752 – 1.14 0.454 90 1171 exclusion phecode
742.2
Pathological, developmental or recurrent
Pathological, developmental or recurrent dislocation
 Musculoskeletal 0.963 0.825 – 1.12 0.634 177 2234 exclusion phecode
742.8 Articular cartilage disorder Musculoskeletal 0.943 0.794 – 1.12 0.501 143 1796 exclusion phecode
742.9 Other derangement of joint Musculoskeletal 1 0.958 – 1.05 0.905 2069 23979 exclusion phecode
743
Osteoporosis, osteopenia and pathological
Osteoporosis, osteopenia and pathological fracture
 Musculoskeletal 1 0.969 – 1.03 0.96 4872 26255 exclusion phecode
743.1 Osteoporosis Musculoskeletal 1.03 0.983 – 1.09 0.2 1924 13563 exclusion phecode
743.11 Osteoporosis NOS Musculoskeletal 1.03 0.981 – 1.09 0.224 1897 13425 exclusion phecode
743.12 Senile osteoporosis Musculoskeletal 1.03 0.921 – 1.16 0.59 344 4146 exclusion phecode
743.13 Other specified osteoporosis Musculoskeletal 0.984 0.824 – 1.18 0.863 132 2177 exclusion phecode
743.2 Pathologic fracture Musculoskeletal 1.01 0.923 – 1.1 0.837 537 7306 exclusion phecode
743.21 Pathologic fracture of vertebrae Musculoskeletal 1.02 0.887 – 1.16 0.816 227 3199 exclusion phecode
743.22 Pathologic fracture of femur Musculoskeletal 1.04 0.813 – 1.34 0.734 68 1011 exclusion phecode
743.4 Stress fracture Musculoskeletal 0.926 0.798 – 1.08 0.318 192 2828 exclusion phecode
743.9
Osteopenia or other disorder of bone and
Osteopenia or other disorder of bone and cartilage
 Musculoskeletal 0.975 0.94 – 1.01 0.171 3522 24956 exclusion phecode
745 Pain in joint Musculoskeletal 0.985 0.962 – 1.01 0.213 10927 20720 exclusion phecode
747 Cardiac and circulatory congenital anomalies Congenital Anomalies 1.02 0.961 – 1.08 0.515 1182 15107 exclusion phecode
747.1 Cardiac congenital anomalies Congenital Anomalies 1.07 1 – 1.15 0.0501 892 11934 exclusion phecode
747.11 Cardiac shunt/ heart septal defect Congenital Anomalies 1.05 0.94 – 1.17 0.395 345 4502 exclusion phecode
747.12 Valvular heart disease/ heart chambers Congenital Anomalies 1.04 0.936 – 1.16 0.444 364 5026 exclusion phecode
747.13 Congenital anomalies of great vessels Congenital Anomalies 1.09 0.945 – 1.26 0.231 201 2812 exclusion phecode
747.2
Congenital anomalies of peripheral vascular
Congenital anomalies of peripheral vascular system
 Congenital Anomalies 0.91 0.807 – 1.03 0.127 303 3459 exclusion phecode
748 Anomalies of respiratory system, congenital Congenital Anomalies 0.994 0.758 – 1.3 0.967 55 722 exclusion phecode
749 Congenital anomalies of face and neck Congenital Anomalies 1.05 0.94 – 1.18 0.383 343 3980 exclusion phecode
749.1 Cleft palate Congenital Anomalies 1.13 0.888 – 1.45 0.313 71 772 exclusion phecode
749.2 Congenital anomalies of skull and face bones Congenital Anomalies 0.873 0.67 – 1.14 0.311 61 785 exclusion phecode
750 Digestive congenital anomalies Congenital Anomalies 0.936 0.849 – 1.03 0.187 453 6029 exclusion phecode
750.1 Upper gastrointestinal congenital anomalies Congenital Anomalies 0.821 0.706 – 0.955 0.0105 183 2477 exclusion phecode
750.11 Esophageal atresia/tracheoesophageal fistula Congenital Anomalies 0.783 0.604 – 1.01 0.064 59 810 exclusion phecode
750.13 Congenital anomalies of mouth/tongue Congenital Anomalies 0.797 0.604 – 1.05 0.11 47 710 exclusion phecode
750.14 Congenital anomalies of esophagus Congenital Anomalies 0.788 0.618 – 1 0.0544 68 914 exclusion phecode
750.15 Congenital anomalies of stomach Congenital Anomalies 0.999 0.708 – 1.41 0.997 34 383 exclusion phecode
750.2 Lower gastrointestinal congenital anomalies Congenital Anomalies 1.04 0.919 – 1.18 0.527 274 3543 exclusion phecode
750.21 Congenital anomalies of intestine Congenital Anomalies 0.995 0.846 – 1.17 0.956 162 2084 exclusion phecode
750.22
Congenital anomaly of gallbladder, bile ducts
Congenital anomaly of gallbladder, bile ducts, liver, pancreas
 Congenital Anomalies 1.1 0.906 – 1.33 0.345 113 1492 exclusion phecode
751 Genitourinary congenital anomalies Congenital Anomalies 1.04 0.982 – 1.11 0.166 1162 13694 exclusion phecode
751.1 Congenital anomalies of genital organs Congenital Anomalies 1.09 0.973 – 1.22 0.14 348 4133 exclusion phecode
751.11 Congenital anomalies of female genital organs Congenital Anomalies 1.11 0.965 – 1.28 0.144 228 2765 exclusion phecode
751.12 Congenital anomalies of male genital organs Congenital Anomalies 1.02 0.829 – 1.26 0.845 94 1089 exclusion phecode
751.2 Congenital anomalies of urinary system Congenital Anomalies 1.04 0.965 – 1.12 0.31 764 9239 exclusion phecode
751.21 Cystic kidney disease Congenital Anomalies 0.989 0.903 – 1.08 0.808 521 6460 exclusion phecode
751.22 Other specified congenital anomalies of kidney Congenital Anomalies 1.1 0.941 – 1.29 0.229 175 2000 exclusion phecode
751.3 Obstructive genitourinary defect Congenital Anomalies 1.11 0.922 – 1.33 0.278 132 1302 exclusion phecode
752 Nervous system congenital anomalies Congenital Anomalies 0.978 0.899 – 1.06 0.613 594 7660 exclusion phecode
752.1 Neural tube defects Congenital Anomalies 0.975 0.889 – 1.07 0.6 488 6154 exclusion phecode
752.11 Spina bifida Congenital Anomalies 0.869 0.712 – 1.06 0.168 108 1286 exclusion phecode
752.2
Other specified congenital anomalies of nervous
Other specified congenital anomalies of nervous system
 Congenital Anomalies 0.954 0.79 – 1.15 0.625 124 1660 exclusion phecode
753 Congenital anomalies of the eye Congenital Anomalies 0.938 0.774 – 1.14 0.517 110 1360 exclusion phecode
753.1 Congenital cataract and lens anomalies Congenital Anomalies 0.948 0.652 – 1.38 0.779 26 400 exclusion phecode
753.2 Congenital anomalies of posterior segment of eye Congenital Anomalies 0.714 0.499 – 1.02 0.0655 33 367 exclusion phecode
754 Congenital musculoskeletal deformities of spine Congenital Anomalies 1.01 0.929 – 1.1 0.815 596 8056 exclusion phecode
754.1 Lumbosacral spondylolysis, congenital Congenital Anomalies 1.1 0.851 – 1.41 0.478 56 915 exclusion phecode
754.2 Spondylolisthesis, congenital Congenital Anomalies 0.947 0.838 – 1.07 0.384 287 3659 exclusion phecode
755 Congenital anomalies of limbs Congenital Anomalies 1.08 0.974 – 1.2 0.144 414 5254 exclusion phecode
755.1 Congenital deformities of feet Congenital Anomalies 1.01 0.868 – 1.18 0.874 193 2462 exclusion phecode
755.4
Congenital anomalies of upper limb, including
Congenital anomalies of upper limb, including shoulder girdle
 Congenital Anomalies 1 0.72 – 1.39 0.992 36 526 exclusion phecode
755.6
Other congenital anomalies of lower limb
Other congenital anomalies of lower limb, including pelvic girdle
 Congenital Anomalies 1.15 0.996 – 1.33 0.0574 198 2374 exclusion phecode
755.61 Congenital hip dysplasia and deformity Congenital Anomalies 1.18 0.982 – 1.42 0.0771 123 1376 exclusion phecode
756 Other congenital musculoskeletal anomalies Congenital Anomalies 0.981 0.909 – 1.06 0.627 724 9440 exclusion phecode
756.1 Congenital anomalies of abdominal wall; diaphram Congenital Anomalies 0.847 0.613 – 1.17 0.314 43 490 exclusion phecode
756.2
Pectus and other congenital anomalies of
Pectus and other congenital anomalies of ribs/sternum
 Congenital Anomalies 1.11 0.848 – 1.44 0.456 53 559 exclusion phecode
756.3
Congenital anomalies of muscle, tendon, fascia
Congenital anomalies of muscle, tendon, fascia, and connective tissue
 Congenital Anomalies 0.943 0.806 – 1.1 0.463 171 2396 exclusion phecode
756.5 Congenital osteodystrophies Congenital Anomalies 0.941 0.86 – 1.03 0.193 505 6769 exclusion phecode
757 Congenital anomalies of the integument Congenital Anomalies 1.05 0.922 – 1.21 0.441 235 2629 exclusion phecode
758 Chromosomal anomalies and genetic disorders Congenital Anomalies 0.905 0.746 – 1.1 0.316 106 1325 exclusion phecode
758.1 Chromosomal anomalies Congenital Anomalies 0.915 0.729 – 1.15 0.442 78 952 exclusion phecode
759 Other and unspecified congenital anomalies Congenital Anomalies 0.974 0.868 – 1.09 0.652 324 3962 exclusion phecode
759.1 Anomalies of endocrine glands, congenital Congenital Anomalies 0.919 0.687 – 1.23 0.571 48 504 exclusion phecode
760 Back pain Symptoms 1.05 1.02 – 1.08 0.000377 8063 23565 exclusion phecode
761 Cervicalgia Symptoms 1.04 0.998 – 1.08 0.0596 2890 28346 exclusion phecode
763
Thoracic or lumbosacral neuritis or
Thoracic or lumbosacral neuritis or radiculitis, unspecified
 Symptoms 1.01 0.958 – 1.06 0.754 1630 22858 exclusion phecode
764 Sciatica Symptoms 1.06 1 – 1.11 0.045 1501 22500 exclusion phecode
765 Cervical radiculitis Symptoms 1.06 0.988 – 1.15 0.0999 764 12337 exclusion phecode
766 Neuralgia, neuritis, and radiculitis NOS Symptoms 1.06 1.01 – 1.1 0.0125 2348 26443 exclusion phecode
767 Cervicocranial/Cervicobrachial syndrome Symptoms 0.941 0.672 – 1.32 0.726 36 805 exclusion phecode
769 Nonallopathic lesions NEC Symptoms 0.966 0.877 – 1.06 0.484 441 7477 exclusion phecode
770 Myalgia and myositis unspecified Symptoms 1.05 1.01 – 1.1 0.0193 2458 24248 exclusion phecode
771 Musculoskeletal symptoms referable to limbs Symptoms 0.995 0.953 – 1.04 0.82 2333 25616 exclusion phecode
771.1 Swelling of limb Symptoms 1.02 0.976 – 1.06 0.431 2577 25561 exclusion phecode
771.2 Cramp of limb Symptoms 0.972 0.873 – 1.08 0.607 359 7300 exclusion phecode
772 Symptoms of the muscles Symptoms 0.979 0.915 – 1.05 0.524 941 14118 exclusion phecode
772.1 Muscular wasting and disuse atrophy Symptoms 1.06 0.927 – 1.22 0.39 231 3039 exclusion phecode
772.2 Spasm of muscle Symptoms 0.99 0.927 – 1.06 0.762 975 16071 exclusion phecode
772.3 Muscle weakness Symptoms 1.01 0.952 – 1.07 0.797 1306 19361 exclusion phecode
772.4 Rhabdomyolysis Symptoms 1.24 0.977 – 1.58 0.0765 64 1120 exclusion phecode
772.6 Facial weakness Symptoms 0.946 0.818 – 1.09 0.449 195 3274 exclusion phecode
780 Hypothermia/Chills Symptoms 0.903 0.774 – 1.05 0.189 176 2955 exclusion phecode
781
Symptoms involving nervous and musculoskeletal
Symptoms involving nervous and musculoskeletal systems
 Symptoms 0.976 0.917 – 1.04 0.453 1064 17724 exclusion phecode
781.1 Loss of height Symptoms 1.12 0.871 – 1.45 0.368 59 819 exclusion phecode
781.2 Abnormal posture Symptoms 0.719 0.462 – 1.12 0.144 18 388 exclusion phecode
782.3 Edema Symptoms 1.01 0.973 – 1.06 0.506 2470 25986 exclusion phecode
782.6 Pallor and flushing Symptoms 1.1 0.998 – 1.21 0.0561 442 6576 exclusion phecode
783 Fever of unknown origin Symptoms 1.02 0.984 – 1.06 0.24 2817 28615 exclusion phecode
783.1 Postprocedural fever Symptoms 1.11 0.943 – 1.31 0.211 161 2067 exclusion phecode
785 Abdominal pain Symptoms 1.03 1 – 1.05 0.029 8959 22676 exclusion phecode
788 Syncope and collapse Symptoms 0.982 0.935 – 1.03 0.484 1698 24695 exclusion phecode
789 Nausea and vomiting Symptoms 1.02 0.988 – 1.05 0.263 5713 25863 exclusion phecode
789.1 Persistent vomiting Symptoms 1.13 1.02 – 1.26 0.0246 368 5757 exclusion phecode
790 Nonspecific findings on examination of blood Symptoms 1.01 0.946 – 1.08 0.795 1012 16081 exclusion phecode
790.1 Elevated sedimentation rate Symptoms 1.15 0.929 – 1.43 0.2 84 1664 exclusion phecode
790.6 Other abnormal blood chemistry Symptoms 1.01 0.977 – 1.05 0.464 3272 27455 exclusion phecode
790.8 Elevated C-reactive protein (CRP) Symptoms 1.03 0.86 – 1.23 0.769 130 2234 exclusion phecode
790.9 Abnormal arterial blood gases Symptoms 1.12 0.87 – 1.45 0.371 59 1098 exclusion phecode
791 Gangrene Symptoms 1.19 1 – 1.41 0.0489 144 1992 exclusion phecode
792
Abnormal Papanicolaou smear of cervix and
Abnormal Papanicolaou smear of cervix and cervical HPV
 Genitourinary 0.966 0.916 – 1.02 0.189 1679 10901 exclusion phecode
792.1
Papanicolaou smear of cervix or vagina with
Papanicolaou smear of cervix or vagina with atypical squamous cells
 Genitourinary 0.967 0.893 – 1.05 0.41 669 7415 exclusion phecode
794
Abnormal results of other function studies
Abnormal results of other function studies (bladder, pancreas, placenta, spleen, etc)
 Symptoms 0.952 0.847 – 1.07 0.41 316 3333 exclusion phecode
795
Other and nonspecific abnormal cytological
Other and nonspecific abnormal cytological, histological and immunological findings
 Symptoms 0.941 0.888 – 0.996 0.0351 1320 14158 exclusion phecode
795.8 Abnormal tumor markers Symptoms 0.956 0.896 – 1.02 0.17 1048 9787 exclusion phecode
795.81 Elevated carcinoembryonic antigen [CEA] Symptoms 1.19 0.853 – 1.65 0.31 39 406 exclusion phecode
795.82 Elevated cancer antigen 125 [CA 125] Symptoms 0.884 0.737 – 1.06 0.183 131 1325 exclusion phecode
796 Elevated prostate specific antigen [PSA] Genitourinary 0.959 0.901 – 1.02 0.183 1244 6435 exclusion phecode
797 Shock Symptoms 1.07 0.937 – 1.22 0.322 245 3909 exclusion phecode
797.1 Cardiogenic shock Symptoms 1.16 0.932 – 1.44 0.183 87 1525 exclusion phecode
798 Malaise and fatigue Symptoms 1.01 0.978 – 1.04 0.589 5028 26588 exclusion phecode
798.1 Chronic fatigue syndrome Symptoms 1.01 0.929 – 1.1 0.832 607 13266 exclusion phecode
800 Fracture of lower limb Injuries & Poisonings 0.995 0.939 – 1.06 0.872 1245 16074 exclusion phecode
800.1 Fracture of neck of femur Injuries & Poisonings 1.01 0.886 – 1.14 0.927 261 3455 exclusion phecode
800.2 Fracture of unspecified part of femur Injuries & Poisonings 1.05 0.939 – 1.17 0.404 353 4651 exclusion phecode
800.3 Fracture of tibia and fibula Injuries & Poisonings 0.938 0.852 – 1.03 0.185 472 6377 exclusion phecode
800.4 Fracture of patella Injuries & Poisonings 1.04 0.889 – 1.21 0.639 173 2485 exclusion phecode
801 Fracture of ankle and foot Injuries & Poisonings 0.974 0.916 – 1.03 0.391 1141 15872 exclusion phecode
801.1 Fracture of foot Injuries & Poisonings 0.946 0.869 – 1.03 0.201 582 7830 exclusion phecode
802 Fracture of pelvis Injuries & Poisonings 1.08 0.936 – 1.24 0.295 207 2647 exclusion phecode
803 Fracture of upper limb Injuries & Poisonings 0.965 0.909 – 1.03 0.25 1192 14255 exclusion phecode
803.1 Fracture of humerus Injuries & Poisonings 1.02 0.92 – 1.13 0.728 416 5164 exclusion phecode
803.2 Fracture of radius and ulna Injuries & Poisonings 0.948 0.875 – 1.03 0.195 642 7827 exclusion phecode
803.21 Colles' fracture Injuries & Poisonings 0.974 0.831 – 1.14 0.743 158 2016 exclusion phecode
803.3 Fracture of clavicle or scapula Injuries & Poisonings 0.863 0.768 – 0.97 0.0139 303 3612 exclusion phecode
804 Fracture of hand or wrist Injuries & Poisonings 1.01 0.946 – 1.08 0.73 925 11347 exclusion phecode
805
Fracture of vertebral column without mention of
Fracture of vertebral column without mention of spinal cord injury
 Injuries & Poisonings 0.97 0.895 – 1.05 0.453 672 9121 exclusion phecode
807 Fracture of ribs Injuries & Poisonings 0.981 0.873 – 1.1 0.745 310 4633 exclusion phecode
809 Fracture of unspecified bones Injuries & Poisonings 0.986 0.937 – 1.04 0.592 1637 20134 exclusion phecode
816 Cerebral laceration and contusion Injuries & Poisonings 0.936 0.622 – 1.41 0.75 24 351 exclusion phecode
817 Concussion Injuries & Poisonings 1.02 0.929 – 1.12 0.695 480 7170 exclusion phecode
818 Intracranial hemorrhage (injury) Injuries & Poisonings 1.09 0.913 – 1.29 0.351 132 2042 exclusion phecode
818.1 Subdural hemorrhage (injury) Injuries & Poisonings 1.11 0.771 – 1.6 0.569 28 590 exclusion phecode
818.2 Subarachnoid hemorrhage (injury) Injuries & Poisonings 1.01 0.751 – 1.37 0.923 40 654 exclusion phecode
819
Skull and face fracture and other intercranial
Skull and face fracture and other intercranial injury
 Injuries & Poisonings 0.997 0.939 – 1.06 0.916 1170 15849 exclusion phecode
830 Dislocation Injuries & Poisonings 0.97 0.928 – 1.02 0.192 2136 24103 exclusion phecode
835 Internal derangement of knee Injuries & Poisonings 0.984 0.927 – 1.04 0.604 1206 15034 exclusion phecode
836 Traumatic arthropathy Injuries & Poisonings 0.962 0.842 – 1.1 0.568 248 3305 exclusion phecode
840 Sprains and strains Injuries & Poisonings 0.988 0.955 – 1.02 0.474 4148 27027 exclusion phecode
840.1 Muscle/tendon sprain Injuries & Poisonings 0.918 0.8 – 1.05 0.22 220 3630 exclusion phecode
840.2 Rotator cuff (capsule) sprain Injuries & Poisonings 1.05 0.977 – 1.14 0.17 723 11014 exclusion phecode
840.3 Joint/ligament sprain Injuries & Poisonings 0.976 0.928 – 1.03 0.358 1703 18018 exclusion phecode
841 Sprains and strains of back and neck Injuries & Poisonings 0.927 0.857 – 1 0.0564 685 11120 exclusion phecode
842 Other sprains and strains Injuries & Poisonings 0.978 0.905 – 1.06 0.582 700 9971 exclusion phecode
850 Hemorrhage or hematoma complicating a procedure Injuries & Poisonings 1.04 0.981 – 1.11 0.179 1157 14151 exclusion phecode
851
Complications of transplants and reattached
Complications of transplants and reattached limbs
 Injuries & Poisonings 1.1 1.05 – 1.16 0.000233 1610 18910 exclusion phecode
853 Complication of colostomy or enterostomy Injuries & Poisonings 1.04 0.917 – 1.18 0.53 258 3193 exclusion phecode
854
Complications of cardiac/vascular device
Complications of cardiac/vascular device, implant, and graft
 Injuries & Poisonings 1.05 0.986 – 1.13 0.12 938 13437 exclusion phecode
855
Complication of nervous system device, implant
Complication of nervous system device, implant, and graft
 Injuries & Poisonings 1.1 0.928 – 1.31 0.27 138 1864 exclusion phecode
856
Vascular complications of surgery and medical
Vascular complications of surgery and medical procedures
 Injuries & Poisonings 1.06 0.895 – 1.25 0.518 155 1995 exclusion phecode
857
Mechanical complication of unspecified
Mechanical complication of unspecified genitourinary device, implant, and graft
 Injuries & Poisonings 1.11 1.03 – 1.2 0.00476 779 9148 exclusion phecode
858 Complication of internal orthopedic device Injuries & Poisonings 1.07 1.01 – 1.13 0.0238 1307 15464 exclusion phecode
859
Complication due to other implant and internal
Complication due to other implant and internal device
 Injuries & Poisonings 1.12 1.05 – 1.19 0.000342 1174 14664 exclusion phecode
860 Bone marrow or stem cell transplant Neoplasms 0.887 0.705 – 1.12 0.307 73 1108 exclusion phecode
870 Open wounds of head; neck; and trunk Injuries & Poisonings 1.02 0.975 – 1.06 0.429 2284 25542 exclusion phecode
870.1 Open wound or laceration of eye or eyelid Injuries & Poisonings 1.11 0.917 – 1.34 0.285 111 1411 exclusion phecode
870.2 Open wound of ear Injuries & Poisonings 0.935 0.747 – 1.17 0.557 82 1005 exclusion phecode
870.3 Other open wound of head and face Injuries & Poisonings 0.96 0.891 – 1.03 0.278 780 9194 exclusion phecode
870.4 Open wound of nose and sinus Injuries & Poisonings 1.04 0.868 – 1.25 0.656 130 1419 exclusion phecode
870.5 Open wound of lip and mouth Injuries & Poisonings 1.05 0.894 – 1.24 0.541 165 1886 exclusion phecode
870.6 Open wound of neck Injuries & Poisonings 1.03 0.861 – 1.22 0.776 152 1449 exclusion phecode
870.8 Open wound of genital organs Injuries & Poisonings 0.987 0.798 – 1.22 0.902 91 1040 exclusion phecode
871 Open wounds of extremities Injuries & Poisonings 1.02 0.972 – 1.07 0.414 1740 22773 exclusion phecode
871.1 Open wound of hand except finger(s) Injuries & Poisonings 0.987 0.872 – 1.12 0.832 281 3930 exclusion phecode
871.2 Open wound of finger(s) Injuries & Poisonings 1.02 0.925 – 1.12 0.717 458 6694 exclusion phecode
871.3 Open wound of foot except toe(s) alone Injuries & Poisonings 1.13 0.98 – 1.31 0.0909 193 3136 exclusion phecode
871.4 Open wound of toe(s) Injuries & Poisonings 0.854 0.703 – 1.04 0.111 100 1921 exclusion phecode
872 Traumatic amputation Injuries & Poisonings 1.03 0.916 – 1.16 0.598 288 3664 exclusion phecode
874 Complication of amputation stump Injuries & Poisonings 1.25 0.977 – 1.6 0.076 68 1119 exclusion phecode
875 Non-healing surgical wound Injuries & Poisonings 1.08 0.962 – 1.21 0.2 332 3919 exclusion phecode
876
Posttraumatic wound infection not elsewhere
Posttraumatic wound infection not elsewhere classified
 Injuries & Poisonings 1.16 1.05 – 1.28 0.005 393 5489 exclusion phecode
907 Injuries to the nervous system Injuries & Poisonings 1.06 0.97 – 1.15 0.208 590 6896 exclusion phecode
910 Superficial injury, infected Injuries & Poisonings 0.819 0.609 – 1.1 0.187 47 754 exclusion phecode
911 Blister Injuries & Poisonings 1.01 0.837 – 1.21 0.929 112 1873 exclusion phecode
912 Insect bite Injuries & Poisonings 0.977 0.846 – 1.13 0.756 202 3241 exclusion phecode
913 Toxic effect of venom Injuries & Poisonings 1.03 0.866 – 1.22 0.766 147 2198 exclusion phecode
916 Contusion Injuries & Poisonings 1.01 0.963 – 1.06 0.7 1918 26533 exclusion phecode
930 Allergic reaction to food Injuries & Poisonings 1.03 0.923 – 1.14 0.64 377 5726 exclusion phecode
931
Contact dermatitis and other eczema due to
Contact dermatitis and other eczema due to plants [except food]
 Dermatologic 0.965 0.864 – 1.08 0.531 330 5134 exclusion phecode
938 Dermatitis due to solar radiation Dermatologic 0.942 0.905 – 0.98 0.00318 2824 21202 exclusion phecode
938.1 Acute dermatitis due to solar radiation Dermatologic 0.946 0.763 – 1.17 0.616 87 1613 exclusion phecode
938.2 Chronic dermatitis due to solar radiation Dermatologic 0.941 0.904 – 0.981 0.00387 2683 20821 exclusion phecode
939
Atopic/contact dermatitis due to other or
Atopic/contact dermatitis due to other or unspecified
 Dermatologic 0.949 0.914 – 0.985 0.00611 3163 24098 exclusion phecode
939.1 Contact and allergic dermatitis of eyelid Dermatologic 1.07 0.787 – 1.45 0.664 42 647 exclusion phecode
941 Adverse reaction to serum or vaccine Injuries & Poisonings 1.23 0.983 – 1.55 0.0704 72 1344 exclusion phecode
942 Infusion and transfusion reaction Injuries & Poisonings 0.967 0.817 – 1.14 0.695 135 2007 exclusion phecode
946 Anaphylactic shock NOS Injuries & Poisonings 0.932 0.812 – 1.07 0.319 219 3618 exclusion phecode
947 Urticaria Dermatologic 0.975 0.895 – 1.06 0.57 580 8657 exclusion phecode
949 Allergies, other Injuries & Poisonings 1 0.965 – 1.04 0.977 3568 24060 exclusion phecode
952
Spinal cord injury without evidence of spinal
Spinal cord injury without evidence of spinal bone injury
 Injuries & Poisonings 1.07 0.944 – 1.21 0.29 271 3318 exclusion phecode
957 Injury to other and unspecified nerves Injuries & Poisonings 1.17 0.928 – 1.47 0.186 77 958 exclusion phecode
958
Certain early complications of trauma or
Certain early complications of trauma or procedure
 Injuries & Poisonings 1.1 1.02 – 1.19 0.0176 673 8226 exclusion phecode
958.1 Postoperative shock Injuries & Poisonings 1.19 0.949 – 1.5 0.131 83 1107 exclusion phecode
958.2 Traumatic and surgical subcutaneous emphysema Injuries & Poisonings 1.07 0.814 – 1.4 0.642 59 757 exclusion phecode
960 Poisoning by antibiotics Injuries & Poisonings 1 0.947 – 1.06 0.919 1315 15714 exclusion phecode
960.1
Adverse effects of antibacterials (not
Adverse effects of antibacterials (not penicillins)
 Injuries & Poisonings 0.972 0.819 – 1.15 0.741 141 2389 exclusion phecode
960.2 Allergy/adverse effect of penicillin Injuries & Poisonings 1.01 0.944 – 1.09 0.729 885 11359 exclusion phecode
961 Poisoning by other anti-infectives Injuries & Poisonings 1.05 0.914 – 1.2 0.511 224 3681 exclusion phecode
961.1 Poisoning/allergy of sulfonamides Injuries & Poisonings 1.15 1.05 – 1.25 0.00226 545 7279 exclusion phecode
962 Poisoning by hormones and synthetic substitutes Injuries & Poisonings 1.09 0.976 – 1.23 0.124 314 5506 exclusion phecode
962.1
Adrenal cortical steroids causing adverse
Adrenal cortical steroids causing adverse effects in therapeutic use
 Injuries & Poisonings 1.04 0.883 – 1.22 0.648 151 2622 exclusion phecode
962.2
Insulins and antidiabetic agents causing
Insulins and antidiabetic agents causing adverse effects in therapeutic use
 Injuries & Poisonings 1.1 0.766 – 1.58 0.602 24 391 exclusion phecode
962.3
Hormones and synthetic substitutes causing
Hormones and synthetic substitutes causing adverse effects in therapeutic use
 Injuries & Poisonings 1.12 0.961 – 1.3 0.15 180 3300 exclusion phecode
963 Poisoning by primarily systemic agents Injuries & Poisonings 0.997 0.944 – 1.05 0.927 1394 17244 exclusion phecode
963.1
Antineoplastic and immunosuppressive drugs
Antineoplastic and immunosuppressive drugs causing adverse effects
 Injuries & Poisonings 1 0.948 – 1.06 0.938 1371 16900 exclusion phecode
964
Poisoning by agents primarily affecting blood
Poisoning by agents primarily affecting blood constituents
 Injuries & Poisonings 1 0.887 – 1.13 0.993 284 5055 exclusion phecode
964.1 Anticoagulants causing adverse effects Injuries & Poisonings 1.04 0.916 – 1.17 0.563 266 4829 exclusion phecode
965
Poisoning by analgesics, antipyretics, and
Poisoning by analgesics, antipyretics, and antirheumatics
 Injuries & Poisonings 1.04 0.944 – 1.15 0.405 419 6170 exclusion phecode
965.1
Opiates and related narcotics causing adverse
Opiates and related narcotics causing adverse effects in therapeutic use
 Injuries & Poisonings 1.08 1 – 1.17 0.0417 691 10261 exclusion phecode
965.3
Salicylates causing adverse effects in
Salicylates causing adverse effects in therapeutic use
 Injuries & Poisonings 0.963 0.766 – 1.21 0.748 82 810 exclusion phecode
966
Poisoning by anticonvulsants and
Poisoning by anticonvulsants and anti-Parkinsonism drugs
 Injuries & Poisonings 1.04 0.754 – 1.42 0.827 37 711 exclusion phecode
967
Adverse effects of sedatives or other central
Adverse effects of sedatives or other central nervous system depressants and anesthetics
 Injuries & Poisonings 1.03 0.944 – 1.12 0.539 600 8877 exclusion phecode
969 Poisoning by psychotropic agents Injuries & Poisonings 1.06 0.853 – 1.31 0.608 82 2043 exclusion phecode
971
Poisoning by drugs primarily affecting the
Poisoning by drugs primarily affecting the autonomic nervous system
 Injuries & Poisonings 1.03 0.714 – 1.49 0.869 29 436 exclusion phecode
972
Poisoning by agents primarily affecting the
Poisoning by agents primarily affecting the cardiovascular system
 Injuries & Poisonings 0.951 0.786 – 1.15 0.603 109 1941 exclusion phecode
972.1
Cardiac rhythm regulators causing adverse
Cardiac rhythm regulators causing adverse effects in therapeutic use
 Injuries & Poisonings 0.809 0.584 – 1.12 0.204 34 539 exclusion phecode
972.6 Antihypertensive agents causing adverse effects Injuries & Poisonings 1 0.754 – 1.34 0.981 42 669 exclusion phecode
974
Poisoning by water, mineral, and uric acid
Poisoning by water, mineral, and uric acid metabolism drugs
 Injuries & Poisonings 1.01 0.701 – 1.44 0.974 26 776 exclusion phecode
975
Poisoning by agents primarily acting on the
Poisoning by agents primarily acting on the smooth and skeletal muscles and respiratory system
 Injuries & Poisonings 1.32 0.887 – 1.96 0.172 25 568 exclusion phecode
976
Poisoning by agents primarily affecting skin &
Poisoning by agents primarily affecting skin & mucous membrane, ophthalmological, otorhinolaryngological, & dental drugs
 Injuries & Poisonings 0.933 0.664 – 1.31 0.686 34 485 exclusion phecode
977 Personal history of allergy to medicinal agents Injuries & Poisonings 1.04 0.965 – 1.12 0.316 784 11726 exclusion phecode
979 Adverse drug events and drug allergies Injuries & Poisonings 0.993 0.943 – 1.05 0.797 1543 21978 exclusion phecode
980
Encounter for long-term (current) use of
Encounter for long-term (current) use of antibiotics
 Infectious Diseases 0.954 0.885 – 1.03 0.222 737 9087 exclusion phecode
985 Toxic effect of other metals Injuries & Poisonings 1.14 0.724 – 1.78 0.577 19 337 exclusion phecode
989
Toxic effect of other substances, chiefly
Toxic effect of other substances, chiefly nonmedicinal as to source
 Injuries & Poisonings 1.11 0.837 – 1.48 0.467 48 784 exclusion phecode
990 Effects radiation NOS Injuries & Poisonings 0.996 0.955 – 1.04 0.864 2502 20747 exclusion phecode
994 Sepsis and SIRS Injuries & Poisonings 1.05 0.981 – 1.12 0.163 974 14356 exclusion phecode
994.1 Systemic inflammatory response syndrome (SIRS) Injuries & Poisonings 0.882 0.732 – 1.06 0.188 122 1942 exclusion phecode
994.2 Sepsis Injuries & Poisonings 1.06 0.993 – 1.14 0.0785 925 13676 exclusion phecode
994.21 Septic shock Injuries & Poisonings 1.02 0.895 – 1.16 0.772 256 4055 exclusion phecode
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