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Scores Sleeplessness / insomnia Michigan Genomics Initiative Freeze 3 (MGI) PheWAS analysis

Sleeplessness / insomnia — Michigan Genomics Initiative Freeze 3 (MGI) PRS PheWAS

PRS model
PRS ID exprsweb-insomnia-1200-prscs-mgi-freeze3-20211120Legacy PRSCSPRS-CSUK Biobank GWAS

Evaluation cohort: Michigan Genomics Initiative Freeze 3 (MGI).

This page pairs the PheWAS plot with the full sortable table for the all-subject and exclusion scans.

Read the all-subject and exclusion scans separately. The combined view is only a browsing aid, and the selected-phecode panel below is only meaningful when the same phecode exists in both scans.

ExPRS exclusion definition

Exclusion cohort: individuals without Sleeplessness / insomnia.

For this ExPRS, the exclusion sensitivity scan removes individuals with the exposure itself before rerunning the PheWAS. This is an exposure-based sensitivity analysis rather than a diagnosis-based exclusion.

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377 rows visible 17 categories
Phecode Description Category OR 95% CI P value Cases Controls Analysis Link
008 Intestinal infection Infectious Diseases 1.01 0.971 – 1.05 0.679 3004 29292 all phecode
008.5 Bacterial enteritis Infectious Diseases 1.01 0.955 – 1.07 0.703 1322 13162 all phecode
008.52 Intestinal infection due to C. difficile Infectious Diseases 0.994 0.932 – 1.06 0.85 1046 10455 all phecode
008.6 Viral Enteritis Infectious Diseases 1.03 0.956 – 1.11 0.448 770 7676 all phecode
010 Tuberculosis Infectious Diseases 0.986 0.862 – 1.13 0.843 244 2425 all phecode
031 Diseases due to other mycobacteria Infectious Diseases 0.918 0.739 – 1.14 0.44 86 855 all phecode
038 Septicemia Infectious Diseases 1.06 1.02 – 1.1 0.00579 2582 24779 all phecode
038.1 Gram negative septicemia Infectious Diseases 1.08 0.988 – 1.18 0.0895 568 5629 all phecode
038.2 Gram positive septicemia Infectious Diseases 1.07 0.935 – 1.22 0.332 235 2350 all phecode
038.3 Bacteremia Infectious Diseases 1.06 0.996 – 1.12 0.0699 1210 12079 all phecode
041 Bacterial infection NOS Infectious Diseases 1.06 1.03 – 1.09 3.73e-05 5750 38799 all phecode
041.1 Staphylococcus infections Infectious Diseases 1.08 1.02 – 1.13 0.00479 1707 16977 all phecode
041.11 Methicillin sensitive Staphylococcus aureus Infectious Diseases 1.03 0.964 – 1.1 0.365 920 9192 all phecode
041.12 Methicillin resistant Staphylococcus aureus Infectious Diseases 1.05 0.976 – 1.13 0.192 783 7812 all phecode
041.2 Streptococcus infection Infectious Diseases 1.06 1.01 – 1.12 0.0209 1632 16287 all phecode
041.21 Rheumatic fever / chorea Infectious Diseases 1.12 0.981 – 1.28 0.0947 257 2554 all phecode
041.4 E. coli Infectious Diseases 1.04 0.974 – 1.1 0.265 1175 11680 all phecode
041.8 H. pylori Infectious Diseases 1.14 1 – 1.3 0.0487 257 2521 all phecode
041.9 Infection with drug-resistant microorganisms Infectious Diseases 1.15 1.04 – 1.28 0.00804 387 3864 all phecode
053 Herpes zoster Infectious Diseases 1.04 0.99 – 1.1 0.117 1560 15184 all phecode
053.1 Herpes zoster with nervous system complications Infectious Diseases 1.12 0.976 – 1.29 0.106 220 2169 all phecode
054 Herpes simplex Infectious Diseases 0.955 0.906 – 1.01 0.0813 1593 15600 all phecode
070 Viral hepatitis Infectious Diseases 1.06 0.981 – 1.14 0.146 829 8280 all phecode
070.1 Viral hepatitis A Infectious Diseases 0.946 0.762 – 1.17 0.615 87 860 all phecode
070.2 Viral hepatitis B Infectious Diseases 1.04 0.904 – 1.2 0.574 215 2138 all phecode
070.3 Viral hepatitis C Infectious Diseases 1.1 1 – 1.2 0.0469 528 5280 all phecode
070.4 Chronic hepatitis Infectious Diseases 0.987 0.855 – 1.14 0.86 197 1964 all phecode
070.9 Hepatitis NOS Infectious Diseases 1.04 0.973 – 1.1 0.274 1145 11381 all phecode
071 Human immunodeficiency virus [HIV] disease Infectious Diseases 1.01 0.852 – 1.2 0.913 145 1450 all phecode
071.1 HIV infection, symptomatic Infectious Diseases 0.952 0.786 – 1.15 0.612 117 1163 all phecode
078 Viral warts & HPV Infectious Diseases 0.953 0.92 – 0.988 0.00853 3434 29624 all phecode
079 Viral infection Infectious Diseases 0.974 0.948 – 1 0.0519 6664 35342 all phecode
079.1 Varicella infection Infectious Diseases 0.955 0.923 – 0.988 0.00836 3793 31251 all phecode
079.2 Infectious mononucleosis Infectious Diseases 1.05 0.933 – 1.19 0.398 283 2723 all phecode
079.9 Viremia, NOS Infectious Diseases 1.03 0.963 – 1.11 0.349 838 8253 all phecode
080 Postoperative infection Infectious Diseases 1.06 1.02 – 1.11 0.00253 2619 26065 all phecode
081
Infection/inflammation of internal prosthetic
Infection/inflammation of internal prosthetic device; implant; and graft
 Infectious Diseases 1.06 1.01 – 1.12 0.0224 1589 15884 all phecode
090
Sexually transmitted infections (not HIV or
Sexually transmitted infections (not HIV or hepatitis)
 Infectious Diseases 0.958 0.896 – 1.02 0.211 965 9630 all phecode
110 Dermatophytosis / Dermatomycosis Infectious Diseases 0.974 0.94 – 1.01 0.146 3544 30054 all phecode
110.1 Dermatophytosis Infectious Diseases 0.967 0.931 – 1 0.0754 3241 27244 all phecode
110.11 Dermatophytosis of nail Infectious Diseases 0.973 0.929 – 1.02 0.26 2044 16765 all phecode
110.12 Althete's foot Infectious Diseases 0.963 0.898 – 1.03 0.288 899 8043 all phecode
110.13 Dermatophytosis of the body Infectious Diseases 0.987 0.917 – 1.06 0.734 790 7827 all phecode
110.2 Dermatomycoses Infectious Diseases 0.989 0.89 – 1.1 0.837 398 3971 all phecode
112 Candidiasis Infectious Diseases 1.04 1 – 1.07 0.0415 3685 30495 all phecode
112.3 Candidiasis of skin and nails Infectious Diseases 1.07 0.985 – 1.15 0.113 682 6732 all phecode
117 Mycoses Infectious Diseases 0.992 0.911 – 1.08 0.858 608 6069 all phecode
117.1 Histoplasmosis Infectious Diseases 0.973 0.779 – 1.21 0.809 81 801 all phecode
117.4 Aspergillosis Infectious Diseases 0.986 0.826 – 1.18 0.872 140 1387 all phecode
130 Spirochetal infection Infectious Diseases 0.889 0.758 – 1.04 0.145 168 1677 all phecode
130.1 Lyme disease Infectious Diseases 0.934 0.774 – 1.13 0.479 116 1160 all phecode
131 Protozoan infection Infectious Diseases 1.15 0.881 – 1.5 0.306 61 610 all phecode
132 Infestation (lice, mites) Infectious Diseases 0.885 0.764 – 1.02 0.0991 195 1948 all phecode
134 Helminthiases Infectious Diseases 0.931 0.743 – 1.17 0.538 83 812 all phecode
134.1 Intestinal helminthiases Infectious Diseases 0.98 0.736 – 1.31 0.891 53 513 all phecode
136 Other infectious and parasitic diseases Infectious Diseases 1.06 1.02 – 1.1 0.00321 3279 32486 all phecode
145 Cancer of mouth Neoplasms 1 0.949 – 1.06 0.949 1481 14725 all phecode
145.1 Cancer of lip Neoplasms 1.02 0.795 – 1.32 0.855 76 750 all phecode
145.2 Cancer of tongue Neoplasms 1.01 0.932 – 1.1 0.774 645 6430 all phecode
145.3 Cancer of major salivary glands Neoplasms 0.948 0.85 – 1.06 0.335 361 3597 all phecode
145.4 Cancer of the gums Neoplasms 0.973 0.83 – 1.14 0.741 166 1632 all phecode
145.5 Cancer of the mouth floor Neoplasms 1.11 0.957 – 1.28 0.169 206 2048 all phecode
149 Cancer of larynx, pharynx, nasal cavities Neoplasms 0.976 0.922 – 1.03 0.418 1290 12873 all phecode
149.1 Cancer of oropharynx Neoplasms 1.13 1.01 – 1.26 0.0388 350 3499 all phecode
149.2 Cancer of nasopharynx Neoplasms 1 0.814 – 1.23 0.987 100 1000 all phecode
149.3 Cancer of hypopharynx Neoplasms 0.906 0.718 – 1.14 0.403 82 819 all phecode
149.4 Cancer of larynx Neoplasms 1.02 0.914 – 1.13 0.754 386 3857 all phecode
149.5
Hx of malignant neoplasm of oral cavity and
Hx of malignant neoplasm of oral cavity and pharynx
 Neoplasms 0.972 0.89 – 1.06 0.53 552 5505 all phecode
149.9 Cancer of of nasal cavities Neoplasms 0.976 0.855 – 1.11 0.714 240 2398 all phecode
150 Cancer of esophagus Neoplasms 0.952 0.862 – 1.05 0.328 433 4315 all phecode
151 Cancer of stomach Neoplasms 1.1 0.998 – 1.2 0.0548 498 4962 all phecode
153 Colorectal cancer Neoplasms 1.01 0.959 – 1.07 0.657 1458 14383 all phecode
153.2 Colon cancer Neoplasms 1.01 0.951 – 1.08 0.717 1160 11472 all phecode
153.3
Malignant neoplasm of rectum, rectosigmoid
Malignant neoplasm of rectum, rectosigmoid junction, and anus
 Neoplasms 0.988 0.918 – 1.06 0.74 815 8093 all phecode
155 Cancer of liver and intrahepatic bile duct Neoplasms 1.06 0.967 – 1.17 0.207 511 5097 all phecode
155.1 Malignant neoplasm of liver, primary Neoplasms 1.09 0.972 – 1.22 0.139 344 3433 all phecode
157 Pancreatic cancer Neoplasms 0.962 0.877 – 1.06 0.417 503 5005 all phecode
158
Neoplasm of unspecified nature of digestive
Neoplasm of unspecified nature of digestive system
 Neoplasms 1.06 1.01 – 1.12 0.0222 1623 15759 all phecode
159
Malignant neoplasm of other and ill-defined
Malignant neoplasm of other and ill-defined sites within the digestive organs and peritoneum
 Neoplasms 0.988 0.941 – 1.04 0.618 1818 17869 all phecode
159.2
Malignant neoplasm of small intestine
Malignant neoplasm of small intestine, including duodenum
 Neoplasms 1.07 0.928 – 1.23 0.36 221 2206 all phecode
159.3
Malignant neoplasm of gallbladder and
Malignant neoplasm of gallbladder and extrahepatic bile ducts
 Neoplasms 0.977 0.827 – 1.16 0.789 158 1578 all phecode
159.4
Malignant neoplasm of retroperitoneum and
Malignant neoplasm of retroperitoneum and peritoneum
 Neoplasms 0.846 0.748 – 0.956 0.0074 293 2920 all phecode
164 Cancer of intrathoracic organs Neoplasms 0.987 0.829 – 1.18 0.887 133 1324 all phecode
165 Cancer within the respiratory system Neoplasms 1.06 0.998 – 1.12 0.0605 1336 13340 all phecode
165.1 Cancer of bronchus; lung Neoplasms 1.05 0.985 – 1.12 0.132 1057 10552 all phecode
170 Cancer of bone and connective tissue Neoplasms 0.975 0.928 – 1.02 0.306 1792 17850 all phecode
170.1 Bone cancer Neoplasms 0.957 0.888 – 1.03 0.245 773 7690 all phecode
170.2 Cancer of connective tissue Neoplasms 0.97 0.915 – 1.03 0.3 1266 12632 all phecode
172 Skin cancer Neoplasms 0.963 0.939 – 0.987 0.00324 8608 33186 all phecode
172.1 Melanomas of skin, dx or hx Neoplasms 0.948 0.92 – 0.977 0.00054 5330 30106 all phecode
172.11 Melanomas of skin Neoplasms 0.934 0.9 – 0.971 0.000461 3100 25064 all phecode
172.2 Other non-epithelial cancer of skin Neoplasms 0.971 0.945 – 0.997 0.032 7095 30462 all phecode
172.21 Basal cell carcinoma Neoplasms 0.947 0.913 – 0.981 0.00266 3690 23868 all phecode
172.22 Squamous cell carcinoma Neoplasms 0.982 0.94 – 1.03 0.422 2414 17683 all phecode
172.3 Carcinoma in situ of skin Neoplasms 0.994 0.94 – 1.05 0.818 1482 12326 all phecode
173 Neoplasm of uncertain behavior of skin Neoplasms 0.981 0.936 – 1.03 0.425 1997 18755 all phecode
174 Breast cancer Neoplasms 0.981 0.944 – 1.02 0.341 3186 15514 all phecode
174.1 Breast cancer [female] Neoplasms 0.987 0.948 – 1.03 0.515 3036 14701 all phecode
174.11 Malignant neoplasm of female breast Neoplasms 0.993 0.954 – 1.03 0.75 2991 14639 all phecode
174.3 Neoplasm of uncertain behavior of breast Neoplasms 0.928 0.809 – 1.06 0.287 233 2307 all phecode
175 Acquired absence of breast Neoplasms 0.937 0.875 – 1 0.0629 919 8920 all phecode
180 Cervical cancer and dysplasia Neoplasms 1.01 0.959 – 1.07 0.626 1431 12185 all phecode
180.1 Cervical cancer Neoplasms 1.04 0.953 – 1.15 0.351 500 4982 all phecode
180.3
Cervical intraepithelial neoplasia [CIN]
Cervical intraepithelial neoplasia [CIN] [Cervical dysplasia]
 Neoplasms 0.993 0.932 – 1.06 0.842 1048 9323 all phecode
182 Malignant neoplasm of uterus Neoplasms 0.982 0.911 – 1.06 0.634 765 7613 all phecode
184 Cancer of other female genital organs Neoplasms 0.926 0.872 – 0.984 0.0125 1191 11592 all phecode
184.1
Malignant neoplasm of ovary and other uterine
Malignant neoplasm of ovary and other uterine adnexa
 Neoplasms 0.875 0.802 – 0.955 0.00263 573 5719 all phecode
184.11 Malignant neoplasm of ovary Neoplasms 0.864 0.782 – 0.956 0.00443 432 4309 all phecode
184.2
Cancer of other female genital organs
Cancer of other female genital organs (excluding uterus and ovary)
 Neoplasms 0.991 0.91 – 1.08 0.829 608 6057 all phecode
185 Cancer of prostate Neoplasms 1.01 0.967 – 1.05 0.664 2901 10342 all phecode
187 Cancer of other male genital organs Neoplasms 0.985 0.881 – 1.1 0.79 339 3384 all phecode
187.1
Malignant neoplasm of unspecified male genital
Malignant neoplasm of unspecified male genital organ
 Neoplasms 1.04 0.856 – 1.26 0.703 115 1141 all phecode
187.2 Malignant neoplasm of testis Neoplasms 0.974 0.835 – 1.14 0.738 183 1830 all phecode
187.8
Neoplasm of uncertain behavior of male genital
Neoplasm of uncertain behavior of male genital organs
 Neoplasms 0.804 0.608 – 1.06 0.125 57 562 all phecode
189
Cancer of urinary organs (incl. kidney and
Cancer of urinary organs (incl. kidney and bladder)
 Neoplasms 1.04 1 – 1.08 0.0487 2923 23541 all phecode
189.1 Cancer of kidney and renal pelvis Neoplasms 1.04 0.984 – 1.1 0.164 1450 14437 all phecode
189.11 Malignant neoplasm of kidney, except pelvis Neoplasms 1.02 0.966 – 1.09 0.415 1267 12655 all phecode
189.12 Malignant neoplasm of renal pelvis Neoplasms 1.05 0.917 – 1.2 0.481 237 2347 all phecode
189.2 Cancer of bladder Neoplasms 1.04 0.994 – 1.1 0.0867 1783 15224 all phecode
189.21 Malignant neoplasm of bladder Neoplasms 1.04 0.986 – 1.09 0.156 1657 14178 all phecode
189.4 Malignant neoplasm of other urinary organs Neoplasms 1.03 0.954 – 1.12 0.411 678 6586 all phecode
190 Cancer of eye Neoplasms 1.1 0.922 – 1.31 0.289 138 1374 all phecode
191
Manlignant and unknown neoplasms of brain and
Manlignant and unknown neoplasms of brain and nervous system
 Neoplasms 0.978 0.918 – 1.04 0.498 1078 10771 all phecode
191.1 Cancer of brain and nervous system Neoplasms 0.974 0.901 – 1.05 0.514 706 7052 all phecode
191.11 Cancer of brain Neoplasms 1.01 0.923 – 1.09 0.906 600 5996 all phecode
193 Thyroid cancer Neoplasms 1.04 0.969 – 1.11 0.291 945 9393 all phecode
194 Cancer of other endocrine glands Neoplasms 1.1 1.01 – 1.2 0.0248 579 5759 all phecode
195 Cancer, suspected or other Neoplasms 0.99 0.97 – 1.01 0.365 16962 26401 all phecode
195.1 Malignant neoplasm, other Neoplasms 0.989 0.968 – 1.01 0.298 16670 26384 all phecode
195.3 Malignant neoplasm of head, face, and neck Neoplasms 1.01 0.947 – 1.07 0.784 1103 9766 all phecode
196 Radiotherapy Neoplasms 0.971 0.93 – 1.01 0.187 2427 17006 all phecode
197 Chemotherapy Neoplasms 0.971 0.941 – 1 0.0719 4952 23797 all phecode
198 Secondary malignant neoplasm Neoplasms 0.978 0.949 – 1.01 0.14 5801 23481 all phecode
198.1 Secondary malignancy of lymph nodes Neoplasms 0.978 0.944 – 1.01 0.235 3677 21489 all phecode
198.2 Secondary malignancy of respiratory organs Neoplasms 0.988 0.927 – 1.05 0.714 1072 10334 all phecode
198.3
Secondary malignant neoplasm of digestive
Secondary malignant neoplasm of digestive systems
 Neoplasms 0.911 0.849 – 0.978 0.01 866 8538 all phecode
198.4 Secondary malignant neoplasm of liver Neoplasms 0.986 0.915 – 1.06 0.719 767 7558 all phecode
198.5 Secondary malignancy of brain/spine Neoplasms 0.924 0.851 – 1 0.0571 640 6338 all phecode
198.6 Secondary malignancy of bone Neoplasms 0.974 0.907 – 1.05 0.461 866 8307 all phecode
198.7 Secondary malignant neoplasm of skin Neoplasms 0.861 0.766 – 0.967 0.0116 336 3253 all phecode
199 Neoplasm of uncertain behavior Neoplasms 0.983 0.954 – 1.01 0.257 5693 25767 all phecode
199.4 Neurofibromatosis Neoplasms 0.834 0.671 – 1.04 0.103 88 880 all phecode
200 Myeloproliferative disease Neoplasms 0.93 0.874 – 0.99 0.0222 1113 11098 all phecode
200.1 Polycythemia vera Neoplasms 0.948 0.827 – 1.09 0.439 231 2310 all phecode
201 Hodgkin's disease Neoplasms 1.01 0.869 – 1.18 0.862 172 1705 all phecode
202 Cancer of other lymphoid, histiocytic tissue Neoplasms 0.949 0.901 – 1 0.0533 1559 15571 all phecode
202.2 Non-Hodgkins lymphoma Neoplasms 0.905 0.855 – 0.958 6e-04 1329 13268 all phecode
202.21 Nodular lymphoma Neoplasms 0.901 0.833 – 0.973 0.00827 693 6923 all phecode
202.22 Reticulosarcoma Neoplasms 0.925 0.789 – 1.08 0.335 170 1693 all phecode
202.24 Large cell lymphoma Neoplasms 0.849 0.72 – 1 0.0514 160 1586 all phecode
204 Leukemia Neoplasms 0.978 0.904 – 1.06 0.584 689 6876 all phecode
204.1 Lymphoid leukemia Neoplasms 0.89 0.78 – 1.02 0.0843 236 2354 all phecode
204.11 Lymphoid leukemia, acute Neoplasms 0.752 0.589 – 0.961 0.0226 74 734 all phecode
204.12 Lymphoid leukemia, chronic Neoplasms 0.907 0.778 – 1.06 0.209 173 1724 all phecode
204.2 Myeloid leukemia Neoplasms 0.974 0.857 – 1.11 0.68 265 2633 all phecode
204.21 Myeloid leukemia, acute Neoplasms 0.97 0.819 – 1.15 0.729 153 1516 all phecode
204.22 Myeloid leukemia, chronic Neoplasms 0.951 0.738 – 1.23 0.699 61 610 all phecode
204.4 Multiple myeloma Neoplasms 1.01 0.879 – 1.16 0.884 217 2162 all phecode
208 Benign neoplasm of colon Neoplasms 1 0.982 – 1.03 0.709 10303 34953 all phecode
209 Neuroendocrine tumors Neoplasms 1.07 0.94 – 1.21 0.318 258 2580 all phecode
210 Benign neoplasm of lip, oral cavity, and pharynx Neoplasms 0.985 0.939 – 1.03 0.534 1891 18839 all phecode
211
Benign neoplasm of other parts of digestive
Benign neoplasm of other parts of digestive system
 Neoplasms 1.05 1.02 – 1.08 2e-04 7329 36606 all phecode
212
Benign neoplasm of respiratory and
Benign neoplasm of respiratory and intrathoracic organs
 Neoplasms 1.03 0.979 – 1.08 0.277 1843 18412 all phecode
213 Benign neoplasm of bone and articular cartilage Neoplasms 0.981 0.933 – 1.03 0.468 1677 15527 all phecode
214 Lipoma Neoplasms 0.977 0.925 – 1.03 0.394 1437 14132 all phecode
214.1 Lipoma of skin and subcutaneous tissue Neoplasms 0.975 0.908 – 1.05 0.475 883 8710 all phecode
215
Other benign neoplasm of connective and other
Other benign neoplasm of connective and other soft tissue
 Neoplasms 1.01 0.979 – 1.04 0.537 4528 39509 all phecode
216 Benign neoplasm of skin Neoplasms 0.958 0.938 – 0.979 9.87e-05 11528 34919 all phecode
216.1 Screening for malignant neoplasms of the skin Neoplasms 0.958 0.822 – 1.12 0.578 174 1701 all phecode
217 Vascular hamartomas and non-neoplastic nevi Neoplasms 0.928 0.883 – 0.976 0.00336 1786 17184 all phecode
217.1 Nevus, non-neoplastic Neoplasms 0.916 0.87 – 0.964 0.000785 1679 16116 all phecode
218 Benign neoplasm of uterus Neoplasms 0.99 0.957 – 1.02 0.568 4301 16661 all phecode
218.1 Uterine leiomyoma Neoplasms 1.01 0.959 – 1.06 0.774 1835 15733 all phecode
218.2 Other benign neoplasm of uterus Neoplasms 0.98 0.944 – 1.02 0.297 3403 16447 all phecode
220 Benign neoplasm of ovary Neoplasms 0.943 0.88 – 1.01 0.101 893 8783 all phecode
221 Benign neoplasm of other female genital organs Neoplasms 0.993 0.948 – 1.04 0.781 2042 14248 all phecode
222 Benign neoplasm of male genital organs Neoplasms 1.01 0.945 – 1.07 0.843 1133 10663 all phecode
223
Benign neoplasm of kidney and other urinary
Benign neoplasm of kidney and other urinary organs
 Neoplasms 0.996 0.948 – 1.05 0.887 1801 12657 all phecode
224 Benign neoplasm of eye Neoplasms 0.978 0.903 – 1.06 0.578 691 6752 all phecode
224.1 Benign neoplasm of eye, uveal Neoplasms 0.974 0.895 – 1.06 0.54 595 5773 all phecode
225
Benign neoplasm of brain and other parts of
Benign neoplasm of brain and other parts of nervous system
 Neoplasms 1.01 0.951 – 1.07 0.767 1209 12074 all phecode
225.1
Benign neoplasm of brain, cranial nerves
Benign neoplasm of brain, cranial nerves, meninges
 Neoplasms 1 0.938 – 1.07 0.919 947 9454 all phecode
225.2 Benign neoplasm of spinal cord, meninges Neoplasms 1.02 0.901 – 1.15 0.798 289 2890 all phecode
226 Benign neoplasm of thyroid glands Neoplasms 0.966 0.913 – 1.02 0.24 1329 13264 all phecode
227
Benign neoplasm of other endocrine glands and
Benign neoplasm of other endocrine glands and related structures
 Neoplasms 0.944 0.897 – 0.992 0.0241 1690 16896 all phecode
227.1 Benign neoplasm of adrenal gland Neoplasms 0.987 0.897 – 1.09 0.79 467 4644 all phecode
227.2 Benign neoplasm of parathyroid gland Neoplasms 0.93 0.864 – 1 0.0521 795 7941 all phecode
227.3
Benign neoplasm of pituitary gland and
Benign neoplasm of pituitary gland and craniopharyngeal duct (pouch)
 Neoplasms 0.956 0.866 – 1.06 0.376 435 4350 all phecode
228 Hemangioma and lymphangioma, any site Neoplasms 0.955 0.913 – 0.999 0.0465 2149 20946 all phecode
228.1 Hemangioma of skin and subcutaneous tissue Neoplasms 0.957 0.904 – 1.01 0.132 1356 13336 all phecode
229 Benign neoplasm of unspecified sites Neoplasms 0.968 0.944 – 0.993 0.0114 7767 36615 all phecode
229.1 Benign neoplasm of lymph nodes Neoplasms 0.977 0.95 – 1.01 0.11 5743 34218 all phecode
240 Simple and unspecified goiter Endocrine/metabolic 0.998 0.935 – 1.06 0.948 1031 9761 all phecode
241 Nontoxic nodular goiter Endocrine/metabolic 0.987 0.949 – 1.03 0.506 2910 22227 all phecode
241.1 Nontoxic uninodular goiter Endocrine/metabolic 0.985 0.943 – 1.03 0.498 2265 19902 all phecode
241.2 Nontoxic multinodular goiter Endocrine/metabolic 1.01 0.957 – 1.07 0.648 1304 12479 all phecode
242 Thyrotoxicosis with or without goiter Endocrine/metabolic 1.01 0.96 – 1.07 0.604 1400 13425 all phecode
242.1 Graves' disease Endocrine/metabolic 1.02 0.926 – 1.12 0.722 515 5068 all phecode
242.2 Toxic multinodular goiter Endocrine/metabolic 1.01 0.84 – 1.21 0.921 124 1224 all phecode
242.3 Exophthalmos Endocrine/metabolic 0.939 0.831 – 1.06 0.311 292 2898 all phecode
242.31 Thyrotoxic exophthalmos Endocrine/metabolic 0.958 0.804 – 1.14 0.628 144 1432 all phecode
244 Hypothyroidism Endocrine/metabolic 1.01 0.987 – 1.04 0.351 8099 32717 all phecode
244.1 Secondary hypothyroidism Endocrine/metabolic 0.996 0.948 – 1.05 0.883 1762 17230 all phecode
244.2 Acquired hypothyroidism Endocrine/metabolic 1 0.946 – 1.07 0.897 1261 11982 all phecode
244.4 Hypothyroidism NOS Endocrine/metabolic 1.01 0.982 – 1.04 0.545 7542 32208 all phecode
245 Thyroiditis Endocrine/metabolic 0.967 0.899 – 1.04 0.364 832 7882 all phecode
245.2 Chronic thyroiditis Endocrine/metabolic 0.973 0.897 – 1.06 0.508 686 6517 all phecode
245.21 Chronic lymphocytic thyroiditis Endocrine/metabolic 0.971 0.894 – 1.05 0.474 679 6449 all phecode
246 Other disorders of thyroid Endocrine/metabolic 1.02 0.988 – 1.05 0.253 6129 30240 all phecode
246.2 Thyroid cyst Endocrine/metabolic 1.06 0.851 – 1.32 0.603 101 960 all phecode
246.7 Abnormal results of function study of thyroid Endocrine/metabolic 0.957 0.892 – 1.03 0.219 886 8696 all phecode
249 Secondary diabetes mellitus Endocrine/metabolic 1.11 1.04 – 1.19 0.00235 1150 8340 all phecode
250 Diabetes mellitus Endocrine/metabolic 1.07 1.04 – 1.09 1.12e-08 13947 31815 all phecode
250.1 Type 1 diabetes Endocrine/metabolic 1.12 1.05 – 1.18 0.000289 2364 11758 all phecode
250.11 Type 1 diabetes with ketoacidosis Endocrine/metabolic 1.25 1.06 – 1.48 0.00982 262 960 all phecode
250.12 Type 1 diabetes with renal manifestations Endocrine/metabolic 1.11 0.992 – 1.25 0.0693 551 2686 all phecode
250.13 Type 1 diabetes with ophthalmic manifestations Endocrine/metabolic 1.15 1.03 – 1.28 0.0119 784 3018 all phecode
250.14 Type 1 diabetes with neurological manifestations Endocrine/metabolic 1.12 1 – 1.26 0.0455 638 2675 all phecode
250.15
Diabetes type 1 with peripheral circulatory
Diabetes type 1 with peripheral circulatory disorders
 Endocrine/metabolic 1.08 0.889 – 1.31 0.441 155 850 all phecode
250.2 Type 2 diabetes Endocrine/metabolic 1.1 1.07 – 1.13 7.61e-14 9843 29688 all phecode
250.21 Type 2 diabetes with ketoacidosis Endocrine/metabolic 1.11 0.951 – 1.3 0.184 282 1327 all phecode
250.22 Type 2 diabetes with renal manifestations Endocrine/metabolic 1.13 1.07 – 1.19 1.88e-05 1941 13510 all phecode
250.23 Type 2 diabetes with ophthalmic manifestations Endocrine/metabolic 1.09 1.02 – 1.16 0.00768 1643 9668 all phecode
250.24 Type 2 diabetes with neurological manifestations Endocrine/metabolic 1.15 1.09 – 1.21 4.22e-08 2557 16502 all phecode
250.25
Diabetes type 2 with peripheral circulatory
Diabetes type 2 with peripheral circulatory disorders
 Endocrine/metabolic 1.07 0.989 – 1.16 0.0886 860 6143 all phecode
250.3 Insulin pump user Endocrine/metabolic 1.09 1.05 – 1.14 5.26e-05 3496 20809 all phecode
250.4 Abnormal glucose Endocrine/metabolic 1.03 1 – 1.06 0.0422 8385 30645 all phecode
250.41 Impaired fasting glucose Endocrine/metabolic 1.01 0.964 – 1.07 0.585 1870 15861 all phecode
250.42 Other abnormal glucose Endocrine/metabolic 1.03 0.999 – 1.06 0.056 7553 30071 all phecode
250.5 Glycosuria or Acetonuria Endocrine/metabolic 1.09 0.905 – 1.31 0.365 136 1067 all phecode
250.6 Polyneuropathy in diabetes Endocrine/metabolic 1.14 1.08 – 1.2 5.55e-06 2132 13390 all phecode
250.7 Diabetic retinopathy Endocrine/metabolic 1.03 0.974 – 1.09 0.302 1691 10517 all phecode
251 Other disorders of pancreatic internal secretion Endocrine/metabolic 1.08 1.01 – 1.16 0.019 991 8469 all phecode
251.1 Hypoglycemia Endocrine/metabolic 1.11 1.04 – 1.19 0.00194 1207 8570 all phecode
252 Disorders of parathyroid gland Endocrine/metabolic 1.01 0.968 – 1.06 0.625 2282 22119 all phecode
252.1 Hyperparathyroidism Endocrine/metabolic 1.01 0.965 – 1.06 0.652 2088 20335 all phecode
252.2 Hypoparathyroidism Endocrine/metabolic 1.01 0.919 – 1.11 0.857 508 5073 all phecode
253
Disorders of the pituitary gland and its
Disorders of the pituitary gland and its hypothalamic control
 Endocrine/metabolic 0.99 0.921 – 1.06 0.776 859 8544 all phecode
253.1 Pituitary hyperfunction Endocrine/metabolic 0.96 0.845 – 1.09 0.53 263 2621 all phecode
253.11 Acromegaly and gigantism Endocrine/metabolic 0.989 0.784 – 1.25 0.925 83 826 all phecode
253.2 Pituitary hypofunction Endocrine/metabolic 1.19 1.03 – 1.37 0.0171 226 2250 all phecode
253.3 Diabetes insipidus Endocrine/metabolic 0.948 0.76 – 1.18 0.636 86 860 all phecode
253.4 Anterior pituitary disorders Endocrine/metabolic 1.11 0.914 – 1.34 0.297 121 1209 all phecode
253.7 Other disorders of neurohypophysis Endocrine/metabolic 0.872 0.716 – 1.06 0.174 108 1080 all phecode
255 Disorders of adrenal glands Endocrine/metabolic 1.03 0.979 – 1.09 0.24 1506 14869 all phecode
255.1 Adrenal hyperfunction Endocrine/metabolic 0.991 0.891 – 1.1 0.864 373 3730 all phecode
255.11 Cushing's syndrome Endocrine/metabolic 0.985 0.849 – 1.14 0.846 183 1830 all phecode
255.12 Hyperaldosteronism Endocrine/metabolic 0.898 0.747 – 1.08 0.249 135 1350 all phecode
255.2 Adrenal hypofunction Endocrine/metabolic 1.06 0.974 – 1.15 0.179 626 6239 all phecode
255.21 Glucocorticoid deficiency Endocrine/metabolic 1.05 0.962 – 1.14 0.286 596 5941 all phecode
256 Ovarian dysfunction Endocrine/metabolic 0.949 0.893 – 1.01 0.0972 1146 10513 all phecode
256.4 Polycystic ovaries Endocrine/metabolic 1.01 0.939 – 1.09 0.741 742 7128 all phecode
257 Testicular dysfunction Endocrine/metabolic 1 0.937 – 1.07 0.976 1015 9238 all phecode
257.1 Testicular hypofunction Endocrine/metabolic 1.01 0.94 – 1.08 0.876 983 8933 all phecode
258 Iatrogenic endocrine disorders Endocrine/metabolic 1.29 1.04 – 1.61 0.0215 91 910 all phecode
258.1 Postablative ovarian failure Endocrine/metabolic 0.814 0.671 – 0.987 0.0361 109 1090 all phecode
259 Other endocrine disorders Endocrine/metabolic 1.02 0.952 – 1.08 0.637 1038 10259 all phecode
260 Protein-calorie malnutrition Endocrine/metabolic 1.05 1.01 – 1.09 0.014 2880 26812 all phecode
260.1 Cachexia Endocrine/metabolic 1.02 0.902 – 1.15 0.77 292 2911 all phecode
260.2 severe protein-calorie malnutrition Endocrine/metabolic 1.05 0.995 – 1.1 0.0779 1691 16847 all phecode
260.22 Nutritional marasmus Endocrine/metabolic 1.03 0.948 – 1.12 0.482 614 6140 all phecode
260.3 Adult failure to thrive Endocrine/metabolic 1.08 0.999 – 1.18 0.0538 629 6236 all phecode
260.6 Anorexia Endocrine/metabolic 1.03 0.959 – 1.1 0.444 868 8591 all phecode
260.7 Polyphagia Endocrine/metabolic 1.13 0.881 – 1.46 0.331 65 643 all phecode
261 Vitamin deficiency Endocrine/metabolic 0.995 0.97 – 1.02 0.704 7718 35203 all phecode
261.1 Vitamin A deficiency Endocrine/metabolic 1.1 0.862 – 1.4 0.454 69 690 all phecode
261.2 Vitamin B-complex deficiencies Endocrine/metabolic 0.977 0.91 – 1.05 0.527 857 8405 all phecode
261.4 Vitamin D deficiency Endocrine/metabolic 0.999 0.974 – 1.03 0.967 7255 35225 all phecode
261.41 Rickets or osteomalacia Endocrine/metabolic 1.03 0.787 – 1.35 0.826 52 511 all phecode
262 Mineral deficiency NEC Endocrine/metabolic 1.05 0.992 – 1.12 0.0865 1182 11676 all phecode
263 Other nutritional deficiency Endocrine/metabolic 0.976 0.927 – 1.03 0.343 1651 15788 all phecode
264 Lack of normal physiological development Endocrine/metabolic 0.968 0.845 – 1.11 0.634 239 2301 all phecode
264.2 Failure to thrive (childhood) Endocrine/metabolic 1.06 0.875 – 1.29 0.546 122 1220 all phecode
264.9
Lack of normal physiological development
Lack of normal physiological development, unspecified
 Endocrine/metabolic 0.878 0.699 – 1.1 0.26 81 772 all phecode
269 Proteinuria Endocrine/metabolic 1.01 0.96 – 1.06 0.678 1694 13981 all phecode
270
Disorders of protein plasma/amino-acid
Disorders of protein plasma/amino-acid transport and metabolism
 Endocrine/metabolic 1.02 0.953 – 1.09 0.598 967 9575 all phecode
270.1 Disturbances of amino-acid transport Endocrine/metabolic 1.03 0.884 – 1.21 0.669 170 1697 all phecode
270.11
Disturbances of sulphur-bearing amino-acid
Disturbances of sulphur-bearing amino-acid metabolism
 Endocrine/metabolic 0.99 0.828 – 1.18 0.909 134 1334 all phecode
270.2 Disorders of amino-acid metabolism Endocrine/metabolic 1.12 0.914 – 1.37 0.277 96 954 all phecode
270.3 Disorders of plasma protein metabolism Endocrine/metabolic 1.01 0.934 – 1.09 0.835 737 7303 all phecode
270.32 Paraproteinemia Endocrine/metabolic 0.998 0.897 – 1.11 0.978 384 3781 all phecode
270.33 Amyloidosis Endocrine/metabolic 1.16 0.906 – 1.48 0.245 71 695 all phecode
270.34 Alpha-1-antitrypsin deficiency Endocrine/metabolic 1.08 0.834 – 1.39 0.576 69 690 all phecode
270.38
Other specified disorders of plasma protein
Other specified disorders of plasma protein metabolism
 Endocrine/metabolic 1.03 0.914 – 1.16 0.631 299 2984 all phecode
271
Disorders of carbohydrate transport and
Disorders of carbohydrate transport and metabolism
 Endocrine/metabolic 0.989 0.951 – 1.03 0.573 2907 28132 all phecode
271.3
Intestinal disaccharidase deficiencies and
Intestinal disaccharidase deficiencies and disaccharide malabsorption
 Endocrine/metabolic 0.99 0.951 – 1.03 0.604 2827 27425 all phecode
271.9
Other disorders of carbohydrate transport and
Other disorders of carbohydrate transport and metabolism
 Endocrine/metabolic 0.919 0.751 – 1.13 0.415 102 1007 all phecode
272 Disorders of lipoid metabolism Endocrine/metabolic 1.03 1.01 – 1.05 0.00399 18881 26670 all phecode
272.1 Hyperlipidemia Endocrine/metabolic 1.03 1.01 – 1.05 0.00373 18843 26654 all phecode
272.11 Hypercholesterolemia Endocrine/metabolic 1.03 0.998 – 1.06 0.0674 5928 21600 all phecode
272.12 Hyperglyceridemia Endocrine/metabolic 0.985 0.93 – 1.04 0.61 1360 11837 all phecode
272.13 Mixed hyperlipidemia Endocrine/metabolic 1.04 1 – 1.08 0.0496 3538 18449 all phecode
272.9 Unspecified disorder of lipoid metabolism Endocrine/metabolic 1.01 0.894 – 1.13 0.93 313 3011 all phecode
274 Gout and other crystal arthropathies Endocrine/metabolic 1.04 0.999 – 1.09 0.0584 2524 22729 all phecode
274.1 Gout Endocrine/metabolic 1.04 0.997 – 1.09 0.0682 2409 21991 all phecode
274.11 Gouty arthropathy Endocrine/metabolic 0.982 0.921 – 1.05 0.575 1082 10576 all phecode
274.2 Crystal arthropathies Endocrine/metabolic 1.03 0.89 – 1.19 0.692 195 1890 all phecode
274.21 Chondrocalcinosis Endocrine/metabolic 1.03 0.885 – 1.2 0.712 183 1772 all phecode
275 Disorders of mineral metabolism Endocrine/metabolic 1.01 0.982 – 1.05 0.405 4357 37091 all phecode
275.1 Disorders of iron metabolism Hematopoietic 1.06 0.921 – 1.22 0.421 218 2180 all phecode
275.11 Hereditary hemochromatosis Hematopoietic 1.02 0.826 – 1.26 0.85 99 990 all phecode
275.2 Disorders of copper metabolism Endocrine/metabolic 0.982 0.756 – 1.27 0.891 62 614 all phecode
275.3 Disorders of magnesium metabolism Endocrine/metabolic 0.987 0.928 – 1.05 0.662 1154 11504 all phecode
275.5 Disorders of calcium/phosphorus metabolism Endocrine/metabolic 1.01 0.971 – 1.04 0.731 3369 31544 all phecode
275.51 Hypocalcemia Endocrine/metabolic 0.98 0.914 – 1.05 0.568 898 8969 all phecode
275.53 Disorders of phosphorus metabolism Endocrine/metabolic 1.03 0.977 – 1.09 0.243 1366 13634 all phecode
275.6 Hypercalcemia Endocrine/metabolic 0.966 0.914 – 1.02 0.212 1468 14183 all phecode
276
Disorders of fluid, electrolyte, and acid-base
Disorders of fluid, electrolyte, and acid-base balance
 Endocrine/metabolic 1.02 0.997 – 1.04 0.0917 9238 37046 all phecode
276.1 Electrolyte imbalance Endocrine/metabolic 1.01 0.985 – 1.04 0.383 6352 34366 all phecode
276.11 Hyperosmolality and/or hypernatremia Endocrine/metabolic 0.946 0.865 – 1.03 0.226 550 5434 all phecode
276.12 Hyposmolality and/or hyponatremia Endocrine/metabolic 1.01 0.968 – 1.05 0.661 2514 23219 all phecode
276.13 Hyperpotassemia Endocrine/metabolic 1.03 0.994 – 1.07 0.103 2992 25216 all phecode
276.14 Hypopotassemia Endocrine/metabolic 1.02 0.975 – 1.07 0.394 2148 20909 all phecode
276.4 Acid-base balance disorder Endocrine/metabolic 1.05 1 – 1.1 0.0335 2086 20332 all phecode
276.41 Acidosis Endocrine/metabolic 1.07 1.02 – 1.12 0.0099 1788 17572 all phecode
276.42 Alkalosis Endocrine/metabolic 1.02 0.929 – 1.12 0.675 476 4741 all phecode
276.5 Hypovolemia Endocrine/metabolic 1.02 0.993 – 1.06 0.123 4574 34527 all phecode
276.6 Fluid overload Endocrine/metabolic 1.03 0.97 – 1.09 0.363 1384 13211 all phecode
276.8 Polydipsia Endocrine/metabolic 1.22 1.01 – 1.47 0.037 124 1240 all phecode
277 Other disorders of metabolism Endocrine/metabolic 0.994 0.962 – 1.03 0.712 4112 35070 all phecode
277.2
Other disorders of purine and pyrimidine
Other disorders of purine and pyrimidine metabolism
 Endocrine/metabolic 1 0.904 – 1.11 0.965 403 3991 all phecode
277.4 Disorders of bilirubin excretion Endocrine/metabolic 0.989 0.915 – 1.07 0.788 720 7161 all phecode
277.5 Other disorders of lipoid metabolism Endocrine/metabolic 0.979 0.915 – 1.05 0.536 936 9270 all phecode
277.51 Lipoprotein disorders Endocrine/metabolic 0.992 0.921 – 1.07 0.83 773 7668 all phecode
277.7 Dysmetabolic syndrome X Endocrine/metabolic 0.994 0.928 – 1.07 0.862 916 8359 all phecode
278 Overweight, obesity and other hyperalimentation Endocrine/metabolic 1.07 1.05 – 1.09 4.64e-11 19419 27331 all phecode
278.1 Obesity Endocrine/metabolic 1.07 1.05 – 1.09 7.53e-12 17129 27321 all phecode
278.11 Morbid obesity Endocrine/metabolic 1.1 1.07 – 1.13 4.26e-13 8280 27172 all phecode
278.3 Localized adiposity Endocrine/metabolic 1.07 0.947 – 1.2 0.291 324 3228 all phecode
278.4 Abnormal weight gain Endocrine/metabolic 1.02 0.974 – 1.07 0.404 2104 17411 all phecode
279 Disorders involving the immune mechanism Endocrine/metabolic 1.02 0.982 – 1.06 0.296 2934 28612 all phecode
279.1 Immunity deficiency Endocrine/metabolic 1.03 0.968 – 1.09 0.359 1161 11571 all phecode
279.11 Deficiency of humoral immunity Endocrine/metabolic 0.955 0.854 – 1.07 0.425 330 3278 all phecode
279.2 Autoimmune disease NEC Endocrine/metabolic 1.11 1.03 – 1.2 0.00797 754 7516 all phecode
279.7 Other immunological findings Endocrine/metabolic 1 0.97 – 1.03 0.975 4885 36552 all phecode
279.8
Other specified disorders involving the immune
Other specified disorders involving the immune mechanism
 Endocrine/metabolic 1.08 0.992 – 1.17 0.0772 601 5988 all phecode
280 Iron deficiency anemias Hematopoietic 1.02 0.986 – 1.05 0.272 4626 30873 all phecode
280.1
Iron deficiency anemias, unspecified or not due
Iron deficiency anemias, unspecified or not due to blood loss
 Hematopoietic 1.02 0.986 – 1.05 0.289 4484 30649 all phecode
280.2
Iron deficiency anemia secondary to blood loss
Iron deficiency anemia secondary to blood loss (chronic)
 Hematopoietic 1 0.952 – 1.05 0.989 1771 17196 all phecode
281 Other deficiency anemia Hematopoietic 0.965 0.88 – 1.06 0.442 519 5120 all phecode
281.1 Megaloblastic anemia Hematopoietic 0.969 0.849 – 1.11 0.639 253 2497 all phecode
281.11 Pernicious anemia Hematopoietic 0.974 0.804 – 1.18 0.792 114 1108 all phecode
281.12 Other vitamin B12 deficiency anemia Hematopoietic 1.07 0.915 – 1.24 0.415 187 1817 all phecode
281.9 Deficiency anemias Hematopoietic 0.923 0.814 – 1.04 0.205 285 2830 all phecode
282 Hereditary hemolytic anemias Hematopoietic 1.09 0.968 – 1.22 0.157 323 3188 all phecode
282.8 Other hemoglobinopathies Hematopoietic 1.14 0.988 – 1.31 0.074 216 2113 all phecode
282.9 Other hereditary hemolytic anemias Hematopoietic 1.08 0.925 – 1.26 0.331 192 1920 all phecode
283 Acquired hemolytic anemias Hematopoietic 1.04 0.874 – 1.23 0.676 155 1550 all phecode
283.1 Autoimmune hemolytic anemias Hematopoietic 1.27 0.979 – 1.66 0.0717 64 633 all phecode
284 Aplastic anemia Hematopoietic 0.937 0.866 – 1.01 0.101 697 6943 all phecode
284.1 Pancytopenia Hematopoietic 0.927 0.852 – 1.01 0.0729 612 6100 all phecode
285 Other anemias Hematopoietic 1.03 1.01 – 1.05 0.00899 11794 33591 all phecode
285.1 Acute posthemorrhagic anemia Hematopoietic 1.03 0.989 – 1.06 0.172 3325 27709 all phecode
285.2 Anemia of chronic disease Hematopoietic 1.03 0.981 – 1.08 0.247 2055 19939 all phecode
285.21 Anemia in chronic kidney disease Hematopoietic 1.05 0.985 – 1.13 0.126 932 9106 all phecode
285.22 Anemia in neoplastic disease Hematopoietic 0.959 0.886 – 1.04 0.306 690 6892 all phecode
286 Coagulation defects Hematopoietic 1.02 0.99 – 1.06 0.163 3844 33384 all phecode
286.1 Congenital coagulation defects Hematopoietic 1.02 0.9 – 1.16 0.727 250 2466 all phecode
286.11 Von willebrand's disease Hematopoietic 1.04 0.834 – 1.31 0.712 83 822 all phecode
286.12
Congenital deficiency of other clotting factors
Congenital deficiency of other clotting factors (including factor VII)
 Hematopoietic 1.02 0.855 – 1.21 0.847 126 1260 all phecode
286.2
Encounter for long-term (current) use of
Encounter for long-term (current) use of anticoagulants
 Hematopoietic 1.01 0.971 – 1.04 0.705 3354 25918 all phecode
286.3
Coagulation defects complicating pregnancy or
Coagulation defects complicating pregnancy or postpartum
 Hematopoietic 1.07 0.865 – 1.33 0.522 97 962 all phecode
286.4 Acquired coagulation factor deficiency Hematopoietic 1.11 0.97 – 1.26 0.13 254 2529 all phecode
286.5
Hemorrhagic disorder due to intrinsic
Hemorrhagic disorder due to intrinsic circulating anticoagulants
 Hematopoietic 1.1 0.914 – 1.31 0.324 132 1294 all phecode
286.6 Defibrination syndrome Hematopoietic 1.03 0.99 – 1.07 0.14 2579 25377 all phecode
286.7 Other and unspecified coagulation defects Hematopoietic 1.03 0.989 – 1.07 0.166 3014 29294 all phecode
286.8 Hypercoagulable state Hematopoietic 0.966 0.9 – 1.04 0.344 846 8437 all phecode
286.81 Primary hypercoagulable state Hematopoietic 0.965 0.898 – 1.04 0.337 813 8111 all phecode
286.9 Abnormal coagulation profile Hematopoietic 1.07 1.01 – 1.14 0.0254 1182 11487 all phecode
287 Purpura and other hemorrhagic conditions Hematopoietic 0.986 0.95 – 1.02 0.445 3288 28474 all phecode
287.1 Spontaneous ecchymoses Hematopoietic 1.08 0.941 – 1.25 0.264 211 2094 all phecode
287.3 Thrombocytopenia Hematopoietic 0.986 0.949 – 1.02 0.471 2938 26323 all phecode
287.31 Primary thrombocytopenia Hematopoietic 1.06 0.974 – 1.15 0.18 601 5994 all phecode
287.32 Secondary thrombocytopenia Hematopoietic 0.901 0.825 – 0.983 0.0196 569 5686 all phecode
287.4 Qualitative platelet defects Hematopoietic 1.12 0.92 – 1.36 0.263 112 1120 all phecode
288 Diseases of white blood cells Hematopoietic 1.02 0.989 – 1.05 0.213 4886 36527 all phecode
288.1 Decreased white blood cell count Hematopoietic 0.967 0.918 – 1.02 0.203 1599 15951 all phecode
288.11 Neutropenia Hematopoietic 0.947 0.89 – 1.01 0.0918 1106 11041 all phecode
288.2 Elevated white blood cell count Hematopoietic 1.03 0.993 – 1.06 0.122 4082 35079 all phecode
288.3 Eosinophilia Hematopoietic 0.931 0.801 – 1.08 0.353 187 1866 all phecode
289 Other diseases of blood and blood-forming organs Hematopoietic 1 0.953 – 1.05 0.944 1757 17434 all phecode
289.3
Personal history of diseases of blood and
Personal history of diseases of blood and blood-forming organs
 Hematopoietic 1.01 0.94 – 1.08 0.829 918 9087 all phecode
289.4 Lymphadenitis Hematopoietic 0.95 0.919 – 0.982 0.0027 3888 34715 all phecode
289.5 Diseases of spleen Hematopoietic 0.931 0.838 – 1.03 0.177 393 3913 all phecode
289.8 Polycythemia, secondary Hematopoietic 0.99 0.869 – 1.13 0.873 255 2550 all phecode
289.9 Abnormality of red blood cells Hematopoietic 1.01 0.912 – 1.13 0.808 385 3813 all phecode
290
Delirium dementia and amnestic and other
Delirium dementia and amnestic and other cognitive disorders
 Mental Disorders 1.02 0.965 – 1.08 0.459 1318 11547 all phecode
290.1 Dementias Mental Disorders 0.922 0.844 – 1.01 0.0754 541 4910 all phecode
290.11 Alzheimer's disease Mental Disorders 0.907 0.767 – 1.07 0.252 151 1389 all phecode
290.12 Dementia with cerebral degenerations Mental Disorders 0.927 0.747 – 1.15 0.493 88 846 all phecode
290.13 Senile dementia Mental Disorders 0.933 0.834 – 1.04 0.223 340 3078 all phecode
290.16 Vascular dementia Mental Disorders 1.01 0.801 – 1.27 0.931 81 777 all phecode
290.2 Delirium due to conditions classified elsewhere Mental Disorders 1.09 1.01 – 1.18 0.0216 750 7358 all phecode
290.3
Other persistent mental disorders due to
Other persistent mental disorders due to conditions classified elsewhere
 Mental Disorders 1.02 0.949 – 1.09 0.63 886 8618 all phecode
291
Other specified nonpsychotic and/or transient
Other specified nonpsychotic and/or transient mental disorders
 Mental Disorders 1.06 1.01 – 1.1 0.00943 2550 24810 all phecode
291.1
Transient mental disorders due to conditions
Transient mental disorders due to conditions classified elsewhere
 Mental Disorders 1.01 0.868 – 1.18 0.88 175 1750 all phecode
291.4
Specific nonpsychotic mental disorders due to
Specific nonpsychotic mental disorders due to brain damage
 Mental Disorders 0.989 0.9 – 1.09 0.819 484 4807 all phecode
291.8 Alteration of consciousness Mental Disorders 1.07 1.03 – 1.12 0.00248 2036 19974 all phecode
292 Neurological disorders Mental Disorders 1.02 0.996 – 1.05 0.0983 5733 38553 all phecode
292.1 Aphasia/speech disturbance Mental Disorders 0.973 0.929 – 1.02 0.248 2013 19867 all phecode
292.11 Aphasia Mental Disorders 0.936 0.863 – 1.02 0.112 664 6581 all phecode
292.12 Symbolic dysfunction Mental Disorders 0.916 0.791 – 1.06 0.237 200 1988 all phecode
292.2 Mild cognitive impairment Mental Disorders 1.01 0.911 – 1.12 0.836 389 3731 all phecode
292.3 Memory loss Mental Disorders 1 0.957 – 1.05 0.877 1922 18158 all phecode
292.4 Altered mental status Mental Disorders 1.05 1.01 – 1.09 0.0283 2454 22725 all phecode
292.5 Transient alteration of awareness Mental Disorders 0.96 0.869 – 1.06 0.42 430 4285 all phecode
292.6 Hallucinations Mental Disorders 0.998 0.871 – 1.14 0.981 217 2147 all phecode
293 Symptoms involving head and neck Mental Disorders 1.02 0.921 – 1.13 0.706 414 4127 all phecode
293.1
Swelling, mass, or lump in head and neck
Swelling, mass, or lump in head and neck [Space-occupying lesion, intracranial NOS]
 Mental Disorders 0.983 0.953 – 1.02 0.3 4417 38609 all phecode
295 Schizophrenia and other psychotic disorders Mental Disorders 1.09 1.02 – 1.17 0.0129 885 8229 all phecode
295.1 Schizophrenia Mental Disorders 1.13 0.939 – 1.35 0.2 138 1339 all phecode
295.2 Paranoid disorders Mental Disorders 1.16 0.96 – 1.4 0.126 118 1079 all phecode
295.3 Psychosis Mental Disorders 1.1 1.02 – 1.19 0.0141 716 6694 all phecode
296 Mood disorders Mental Disorders 1.1 1.08 – 1.13 3.32e-18 15356 20858 all phecode
296.1 Bipolar Mental Disorders 1.12 1.06 – 1.19 0.000112 1301 11264 all phecode
296.2 Depression Mental Disorders 1.11 1.08 – 1.13 3.23e-19 14833 20856 all phecode
296.22 Major depressive disorder Mental Disorders 1.11 1.09 – 1.14 5.28e-20 13850 20853 all phecode
297 Suicidal ideation or attempt Mental Disorders 1.12 1.05 – 1.2 0.000784 985 9050 all phecode
297.1 Suicidal ideation Mental Disorders 1.15 1.07 – 1.24 0.000262 788 7310 all phecode
297.2 Suicide or self-inflicted injury Mental Disorders 1.22 1.08 – 1.38 0.0018 285 2654 all phecode
300 Anxiety disorders Mental Disorders 1.09 1.07 – 1.12 2.26e-16 15419 20850 all phecode
300.1 Anxiety disorder Mental Disorders 1.09 1.07 – 1.12 1.75e-15 14517 20855 all phecode
300.11 Generalized anxiety disorder Mental Disorders 1.12 1.09 – 1.16 6.17e-13 5546 20512 all phecode
300.12 Agorophobia, social phobia, and panic disorder Mental Disorders 1.1 1.04 – 1.17 0.00133 1360 11377 all phecode
300.13 Phobia Mental Disorders 1.09 1.02 – 1.17 0.00915 1051 9542 all phecode
300.3 Obsessive-compulsive disorders Mental Disorders 1.11 0.989 – 1.25 0.0768 328 3018 all phecode
300.4 Dysthymic disorder Mental Disorders 1.11 1.06 – 1.16 7.31e-06 2420 16552 all phecode
300.8 Acute reaction to stress Mental Disorders 1.13 1.03 – 1.24 0.00867 504 4825 all phecode
300.9 Posttraumatic stress disorder Mental Disorders 1.17 1.09 – 1.26 1.56e-05 843 7909 all phecode
301 Personality disorders Mental Disorders 1.17 1.06 – 1.28 0.0015 477 4539 all phecode
301.2 Antisocial/borderline personality disorder Mental Disorders 1.14 1.01 – 1.3 0.0386 254 2393 all phecode
302 Sexual and gender identity disorders Mental Disorders 1.03 0.988 – 1.07 0.182 3700 13808 all phecode
302.1 Decreased libido Mental Disorders 1.03 0.935 – 1.14 0.53 447 4331 all phecode
303 Psychogenic and somatoform disorders Mental Disorders 1.01 0.978 – 1.03 0.686 6808 20043 all phecode
303.1 Dissociative disorder Mental Disorders 1.34 1.14 – 1.58 0.000372 161 1573 all phecode
303.3 Psychogenic disorder Mental Disorders 0.997 0.968 – 1.03 0.813 6487 19888 all phecode
303.31
Gastrointestinal malfunction arising from
Gastrointestinal malfunction arising from mental factors
 Mental Disorders 1.05 0.957 – 1.16 0.284 471 4623 all phecode
303.4 Somatoform disorder Mental Disorders 1.06 0.994 – 1.12 0.0767 1177 11180 all phecode
304 Adjustment reaction Mental Disorders 1.02 0.983 – 1.05 0.329 3888 20475 all phecode
305.2 Eating disorder Mental Disorders 1.09 1.02 – 1.17 0.0133 901 8329 all phecode
306 Other mental disorder Mental Disorders 1.07 1.02 – 1.13 0.00715 1815 14133 all phecode
306.1 Mental disorders durring/after pregnancy Mental Disorders 1.05 0.957 – 1.15 0.314 587 3527 all phecode
306.9 Tension headache Mental Disorders 1.08 1 – 1.17 0.0437 753 7277 all phecode
312 Conduct disorders Mental Disorders 1.18 1.03 – 1.33 0.0132 254 2501 all phecode
312.3 Impulse control disorder Mental Disorders 1.36 1.08 – 1.73 0.0105 74 736 all phecode
313 Pervasive developmental disorders Mental Disorders 1.1 1.04 – 1.16 0.000501 1571 14633 all phecode
313.1 Attention deficit hyperactivity disorder Mental Disorders 1.09 1.03 – 1.15 0.00219 1392 13190 all phecode
313.2 Tics and stuttering Mental Disorders 1.32 1.04 – 1.67 0.0239 77 770 all phecode
313.3 Autism Mental Disorders 1.01 0.792 – 1.29 0.92 64 621 all phecode
315 Develomental delays and disorders Mental Disorders 1.02 0.942 – 1.11 0.616 684 6788 all phecode
315.1 Learning disorder Mental Disorders 1.2 0.962 – 1.49 0.106 87 860 all phecode
315.2 Speech and language disorder Mental Disorders 0.916 0.803 – 1.04 0.19 254 2539 all phecode
316 Substance addiction and disorders Mental Disorders 1.12 1.08 – 1.16 7.66e-11 3682 32680 all phecode
316.1 Polyneuropathy due to drugs Mental Disorders 0.953 0.878 – 1.03 0.252 634 6331 all phecode
317 Alcohol-related disorders Mental Disorders 1.08 1.03 – 1.12 0.000536 2525 22920 all phecode
317.1 Alcoholism Mental Disorders 1.09 1.04 – 1.14 0.000503 1986 19339 all phecode
317.11 Alcoholic liver damage Mental Disorders 1.06 0.955 – 1.17 0.278 408 4080 all phecode
318 Tobacco use disorder Mental Disorders 1.14 1.11 – 1.16 1.25e-25 8622 34842 all phecode
320 Meningitis Neurological 0.964 0.868 – 1.07 0.487 382 3820 all phecode
323 Encephalitis Neurological 1 0.863 – 1.16 0.986 181 1809 all phecode
323.8 Encephalitis, non-infectious Neurological 0.965 0.82 – 1.14 0.665 153 1527 all phecode
324 Other CNS infection and poliomyelitis Neurological 1.02 0.904 – 1.15 0.734 288 2880 all phecode
325
Phlebitis and thrombophlebitis of intracranial
Phlebitis and thrombophlebitis of intracranial venous sinuses
 Neurological 1.07 0.805 – 1.43 0.628 53 530 all phecode
327 Sleep disorders Neurological 1.06 1.04 – 1.09 6.81e-10 14941 31602 all phecode
327.1 Hypersomnia Neurological 1.06 1.01 – 1.11 0.0131 2061 19110 all phecode
327.3 Sleep apnea Neurological 1.06 1.04 – 1.09 1.03e-07 10909 31304 all phecode
327.31 Central/nonobstroctive sleep apnea Neurological 1.06 0.962 – 1.16 0.249 492 4784 all phecode
327.32 Obstructive sleep apnea Neurological 1.07 1.04 – 1.09 1.43e-07 8744 30530 all phecode
327.4 Insomnia Neurological 1.08 1.05 – 1.12 4.77e-08 5524 30960 all phecode
327.41 Organic or persistent insomnia Neurological 1.06 1 – 1.12 0.051 1265 12120 all phecode
327.5 Parasomnia Neurological 1.09 1.01 – 1.19 0.0376 604 5913 all phecode
327.6 Circadian rhythm sleep disorder Neurological 0.981 0.866 – 1.11 0.764 274 2666 all phecode
327.7 Sleep related movement disorders Neurological 1.17 1.11 – 1.23 5.06e-10 1786 17323 all phecode
327.71 Restless legs syndrome Neurological 1.21 1.14 – 1.27 4.33e-12 1570 15360 all phecode
327.72 Sleep related leg cramps Neurological 1.04 0.829 – 1.3 0.756 83 822 all phecode
331 Other cerebral degenerations Neurological 0.978 0.905 – 1.06 0.579 717 7024 all phecode
331.1 Hydrocephalus Neurological 1.02 0.9 – 1.15 0.791 284 2836 all phecode
331.9 Cerebral degeneration, unspecified Neurological 0.938 0.846 – 1.04 0.22 419 4026 all phecode
332 Parkinson's disease Neurological 0.896 0.808 – 0.994 0.0373 415 4128 all phecode
333
Extrapyramidal disease and abnormal movement
Extrapyramidal disease and abnormal movement disorders
 Neurological 1.1 1.06 – 1.15 1.17e-06 2868 26583 all phecode
333.1 Essential tremor Neurological 1.05 0.968 – 1.13 0.262 725 7163 all phecode
333.2 Myoclonus Neurological 1.09 0.93 – 1.28 0.287 159 1590 all phecode
333.4 Torsion dystonia Neurological 0.934 0.835 – 1.04 0.233 352 3504 all phecode
333.8 Other degenerative diseases of the basal ganglia Neurological 0.958 0.768 – 1.19 0.699 89 890 all phecode
334 Degenerative disease of the spinal cord Neurological 0.986 0.925 – 1.05 0.655 1058 10562 all phecode
334.1 Spinocerebellar disease Neurological 0.955 0.766 – 1.19 0.685 79 790 all phecode
334.2 Anterior horn cell disease Neurological 0.885 0.728 – 1.08 0.221 110 1080 all phecode
334.21 Amyotrophic Lateral Sclerosis Neurological 1.01 0.792 – 1.3 0.91 71 693 all phecode
335 Multiple sclerosis Neurological 0.934 0.842 – 1.04 0.195 396 3951 all phecode
337 Disorders of the autonomic nervous system Neurological 1.09 1.01 – 1.17 0.02 808 7413 all phecode
337.1 Peripheral autonomic neuropathy Neurological 1.12 1 – 1.24 0.0468 370 3164 all phecode
338 Pain Neurological 1.05 1.03 – 1.07 3.45e-08 20346 26417 all phecode
338.1 Acute pain Neurological 1.05 1.03 – 1.07 1.1e-05 15582 26313 all phecode
338.2 Chronic pain Neurological 1.08 1.06 – 1.11 5.3e-12 10994 26368 all phecode
339 Other headache syndromes Neurological 1.08 1.06 – 1.11 7.17e-11 9242 34658 all phecode
340 Migraine Neurological 1.1 1.07 – 1.13 8.42e-11 6708 30587 all phecode
340.1 Migrain with aura Neurological 1.09 1.06 – 1.13 5.95e-07 3624 23684 all phecode
341
Other demyelinating diseases of central nervous
Other demyelinating diseases of central nervous system
 Neurological 0.907 0.757 – 1.09 0.289 133 1330 all phecode
342 Hemiplegia Neurological 1.02 0.923 – 1.12 0.741 464 4607 all phecode
343 Infantile cerebral palsy Neurological 1 0.797 – 1.26 0.978 85 847 all phecode
344 Other paralytic syndromes Neurological 0.969 0.896 – 1.05 0.434 682 6808 all phecode
345 Epilepsy, recurrent seizures, convulsions Neurological 1.06 1.02 – 1.1 0.00577 2553 25307 all phecode
345.1 Epilepsy Neurological 1.03 0.959 – 1.12 0.386 747 7465 all phecode
345.11 Generalized convulsive epilepsy Neurological 1.02 0.887 – 1.16 0.823 233 2330 all phecode
345.12 Partial epilepsy Neurological 1.05 0.963 – 1.15 0.251 534 5335 all phecode
345.3 Convulsions Neurological 1.06 1.01 – 1.1 0.0136 2396 23796 all phecode
346
Abnormal findings on study of brain and/or
Abnormal findings on study of brain and/or nervous system
 Neurological 0.977 0.839 – 1.14 0.767 183 1824 all phecode
346.1
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of skull and head
 Neurological 1 0.952 – 1.06 0.863 1472 14587 all phecode
346.2
Nonspecific abnormal results of function study
Nonspecific abnormal results of function study of brain and central nervous system
 Neurological 0.913 0.758 – 1.1 0.341 120 1181 all phecode
346.3
Nonspecific abnormal findings in cerebrospinal
Nonspecific abnormal findings in cerebrospinal fluid
 Neurological 1.03 0.851 – 1.24 0.769 110 1100 all phecode
347 Cataplexy and narcolepsy Neurological 1 0.819 – 1.22 1 101 1010 all phecode
348 Other conditions of brain Neurological 1.01 0.96 – 1.06 0.742 1793 17894 all phecode
348.2 Cerebral edema and compression of brain Neurological 1 0.937 – 1.08 0.897 905 9034 all phecode
348.4 Cerebral cysts Neurological 1.05 0.917 – 1.2 0.48 229 2290 all phecode
348.7 Coma Neurological 0.949 0.826 – 1.09 0.452 229 2275 all phecode
348.8 Encephalopathy, not elsewhere classified Neurological 1.04 0.969 – 1.12 0.276 853 8479 all phecode
348.9 Other conditions of brain, NOS Neurological 0.984 0.942 – 1.03 0.454 2341 23287 all phecode
349
Other and unspecified disorders of the nervous
Other and unspecified disorders of the nervous system
 Neurological 1.02 0.954 – 1.09 0.544 941 9385 all phecode
350 Abnormal movement Neurological 1.02 0.989 – 1.04 0.256 6706 38762 all phecode
350.1 Abnormal involuntary movements Neurological 1.01 0.978 – 1.05 0.448 3273 30524 all phecode
350.2 Abnormality of gait Neurological 1.01 0.978 – 1.05 0.487 3920 30520 all phecode
350.3 Lack of coordination Neurological 0.975 0.914 – 1.04 0.428 1062 10554 all phecode
350.5 Abnormal reflex Neurological 0.975 0.839 – 1.13 0.745 200 1988 all phecode
350.6 Disturbances of sensation of smell and taste Neurological 0.991 0.907 – 1.08 0.837 558 5576 all phecode
351 Other peripheral nerve disorders Neurological 1.05 1.02 – 1.08 0.000242 7401 34460 all phecode
352 Disorders of other cranial nerves Neurological 1.02 0.973 – 1.08 0.362 1714 17106 all phecode
352.1 Trigeminal nerve disorders [CN5] Neurological 1.03 0.944 – 1.13 0.485 535 5344 all phecode
352.2 Facial nerve disorders [CN7] Neurological 1.02 0.951 – 1.1 0.518 783 7826 all phecode
353 Nerve root and plexus disorders Neurological 1.06 1.03 – 1.1 0.000349 4256 33369 all phecode
353.1 Nerve plexus lesions Neurological 1.02 0.92 – 1.13 0.695 390 3900 all phecode
353.2 Nerve root lesions Neurological 1.06 0.886 – 1.26 0.54 130 1287 all phecode
355 Complex regional/central pain syndrome Neurological 1.1 1.01 – 1.21 0.0342 531 5295 all phecode
355.1 Chronic pain syndrome Neurological 1.17 1.09 – 1.26 2.06e-05 843 8386 all phecode
356 Hereditary and idiopathic peripheral neuropathy Neurological 1.08 1.04 – 1.13 0.000285 2335 20731 all phecode
357 Inflammatory and toxic neuropathy Neurological 1.05 1.01 – 1.09 0.00678 3472 29956 all phecode
358 Myoneural disorders Neurological 1.04 0.98 – 1.11 0.183 1147 11391 all phecode
358.1 Myasthenia gravis Neurological 0.943 0.772 – 1.15 0.569 109 1082 all phecode
359 Muscular dystrophies and other myopathies Neurological 0.977 0.918 – 1.04 0.452 1134 11274 all phecode
359.1 Muscular dystrophies Neurological 1.04 0.798 – 1.37 0.755 64 632 all phecode
359.2 Myopathy Neurological 0.975 0.915 – 1.04 0.423 1092 10843 all phecode
360 Disorders of the globe Sense Organs 0.96 0.801 – 1.15 0.653 131 1276 all phecode
360.2 Progressive myopia Sense Organs 0.936 0.729 – 1.2 0.605 65 640 all phecode
361 Retinal detachments and defects Sense Organs 1.02 0.941 – 1.1 0.679 733 7131 all phecode
361.1 Retinal detachment with retinal defect Sense Organs 1.08 0.955 – 1.22 0.226 302 2962 all phecode
362 Other retinal disorders Sense Organs 0.996 0.96 – 1.03 0.828 3569 22997 all phecode
362.2
Degeneration of macula and posterior pole of
Degeneration of macula and posterior pole of retina
 Sense Organs 0.978 0.934 – 1.02 0.341 2172 15483 all phecode
362.21 Macular degeneration, dry Sense Organs 0.899 0.813 – 0.994 0.0384 419 3438 all phecode
362.22 Macular degeneration, wet Sense Organs 1.02 0.865 – 1.21 0.78 148 1184 all phecode
362.23 Cystoid macular degeneration of retina Sense Organs 1.1 0.993 – 1.22 0.0668 408 3839 all phecode
362.26 Macular puckering of retina Sense Organs 0.978 0.914 – 1.05 0.527 976 8610 all phecode
362.27 Drusen (degenerative) of retina Sense Organs 0.892 0.811 – 0.981 0.0188 488 4558 all phecode
362.29 Macular degeneration (senile) of retina NOS Sense Organs 0.977 0.929 – 1.03 0.346 1883 13955 all phecode
362.3 Other nondiabetic retinopathy Sense Organs 1.02 0.956 – 1.09 0.509 976 8527 all phecode
362.31 Separation of retinal layers Sense Organs 1.02 0.922 – 1.14 0.67 413 4056 all phecode
362.4 Retinal vascular changes and abnomalities Sense Organs 1.03 0.946 – 1.11 0.528 662 5933 all phecode
362.6 Peripheral retinal degenerations Sense Organs 0.995 0.895 – 1.11 0.932 392 3787 all phecode
362.7 Hereditary retinal dystrophies Sense Organs 1.13 0.987 – 1.3 0.0761 215 2103 all phecode
362.8 Retinal hemorrhage/ischemia Sense Organs 0.956 0.836 – 1.09 0.508 241 2368 all phecode
362.9 Retinal edema Sense Organs 1.01 0.898 – 1.14 0.848 324 2936 all phecode
363
Chorioretinal inflammations, scars, and other
Chorioretinal inflammations, scars, and other disorders of choroid
 Sense Organs 1.02 0.932 – 1.13 0.614 492 4746 all phecode
363.3 Chorioretinal scars Sense Organs 1.04 0.924 – 1.16 0.545 332 3184 all phecode
364 Corneal opacity and other disorders of cornea Sense Organs 0.997 0.937 – 1.06 0.934 1132 10772 all phecode
364.1 Corneal opacity Sense Organs 0.865 0.777 – 0.963 0.00785 394 3846 all phecode
364.2 Corneal edema Sense Organs 0.969 0.805 – 1.17 0.744 123 1208 all phecode
364.4 Corneal degenerations Sense Organs 1.05 0.941 – 1.16 0.409 402 3962 all phecode
364.41 Keratoconus Sense Organs 1.12 0.877 – 1.43 0.364 75 739 all phecode
364.5 Corneal dystrophy Sense Organs 0.986 0.898 – 1.08 0.77 502 4682 all phecode
364.51 Fuchs' dystrophy Sense Organs 0.979 0.862 – 1.11 0.738 266 2521 all phecode
364.9 Cornea replaced by transplant Sense Organs 1.05 0.846 – 1.3 0.657 91 885 all phecode
365 Glaucoma Sense Organs 0.989 0.949 – 1.03 0.588 2672 21326 all phecode
365.1 Open-angle glaucoma Sense Organs 0.989 0.914 – 1.07 0.78 705 6491 all phecode
365.11 Primary open angle glaucoma Sense Organs 1 0.906 – 1.11 0.932 403 3681 all phecode
365.2 Primary angle-closure glaucoma Sense Organs 1.1 0.96 – 1.25 0.173 251 2370 all phecode
366 Cataract Sense Organs 0.997 0.971 – 1.02 0.81 8611 28043 all phecode
366.1 Nonsenile Cataract Sense Organs 0.962 0.831 – 1.11 0.603 207 1979 all phecode
366.2 Senile cataract Sense Organs 0.971 0.941 – 1 0.0606 5480 24980 all phecode
367
Disorders of refraction and accommodation
Disorders of refraction and accommodation; blindness and low vision
 Sense Organs 0.982 0.959 – 1.01 0.13 8967 37779 all phecode
367.1 Myopia Sense Organs 0.963 0.934 – 0.993 0.016 5014 34677 all phecode
367.2 Astigmatism Sense Organs 0.958 0.927 – 0.99 0.0105 4161 32463 all phecode
367.8 Hypermetropia Sense Organs 0.99 0.945 – 1.04 0.656 2039 18599 all phecode
367.9 Blindness and low vision Sense Organs 1.05 0.988 – 1.11 0.124 1277 12356 all phecode
368 Visual disturbances Sense Organs 1.02 0.995 – 1.05 0.112 5715 39599 all phecode
368.1 Amblyopia Sense Organs 1.04 0.955 – 1.12 0.396 651 6479 all phecode
368.2 Diplopia and disorders of binocular vision Sense Organs 1.03 0.968 – 1.1 0.333 1087 10786 all phecode
368.3 Anisometropia Sense Organs 0.989 0.859 – 1.14 0.88 219 2168 all phecode
368.4 Visual field defects Sense Organs 0.995 0.935 – 1.06 0.88 1132 11173 all phecode
368.9 Subjective visual disturbances Sense Organs 1.01 0.949 – 1.08 0.726 1070 10620 all phecode
368.91 Psychophysical visual disturbances Sense Organs 1.02 0.848 – 1.23 0.825 120 1171 all phecode
369 Infection of the eye Sense Organs 0.951 0.916 – 0.987 0.00835 3185 28240 all phecode
369.2 Eye infection, viral Sense Organs 0.93 0.847 – 1.02 0.128 502 4954 all phecode
369.5 Conjunctivitis, infectious Sense Organs 0.952 0.914 – 0.991 0.0161 2716 24970 all phecode
370 Keratitis Sense Organs 0.999 0.944 – 1.06 0.964 1365 13169 all phecode
370.1 Corneal ulcer Sense Organs 0.997 0.87 – 1.14 0.96 223 2194 all phecode
370.2 Superficial keratitis Sense Organs 0.966 0.884 – 1.06 0.45 546 5393 all phecode
370.3 Keratoconjunctivitis Sense Organs 1.03 0.953 – 1.12 0.426 649 6263 all phecode
370.31 Keratoconjunctivitis sicca Sense Organs 0.952 0.815 – 1.11 0.538 179 1677 all phecode
371 Inflammation of the eye Sense Organs 0.983 0.952 – 1.02 0.3 4414 32310 all phecode
371.1 Uveitis, noninfectious or NOS Sense Organs 1.02 0.933 – 1.11 0.668 541 5278 all phecode
371.2 Conjunctivitis, noninfectious Sense Organs 0.949 0.886 – 1.02 0.138 906 8939 all phecode
371.21 Allergic conjunctivitis Sense Organs 0.94 0.872 – 1.01 0.105 756 7515 all phecode
371.3 Inflammation of eyelids Sense Organs 0.981 0.946 – 1.02 0.307 3398 26983 all phecode
371.33 Noninfectious dermatoses of eyelid Sense Organs 1.06 0.883 – 1.27 0.544 133 1291 all phecode
372 Disorders of conjunctiva Sense Organs 0.964 0.905 – 1.03 0.247 1118 10728 all phecode
374 Other disorders of eyelids Sense Organs 0.971 0.934 – 1.01 0.141 2940 24188 all phecode
374.1 Ectropion or entropion Sense Organs 0.943 0.853 – 1.04 0.249 431 4084 all phecode
374.2 Lagophthalmos Sense Organs 1.1 0.96 – 1.25 0.177 235 2335 all phecode
374.3 Ptosis of eyelid Sense Organs 0.95 0.893 – 1.01 0.11 1102 10734 all phecode
374.6 Dermatochalasis Sense Organs 0.969 0.908 – 1.03 0.343 1040 9720 all phecode
375 Disorders of lacrimal system Sense Organs 1.02 0.985 – 1.06 0.274 3694 26045 all phecode
375.1 Dry eyes Sense Organs 1.01 0.98 – 1.05 0.422 4040 26751 all phecode
375.2 Epiphora Sense Organs 0.973 0.883 – 1.07 0.589 442 4354 all phecode
376 Disorders of the orbit Sense Organs 0.969 0.869 – 1.08 0.577 352 3508 all phecode
377 Disorders of optic nerve and visual pathways Sense Organs 1.02 0.953 – 1.09 0.545 913 9021 all phecode
377.1 Optic atrophy Sense Organs 0.899 0.792 – 1.02 0.101 283 2793 all phecode
377.3 Optic neuritis/neuropathy Sense Organs 1.04 0.958 – 1.14 0.321 585 5775 all phecode
378
Strabismus and other disorders of binocular eye
Strabismus and other disorders of binocular eye movements
 Sense Organs 0.962 0.908 – 1.02 0.201 1275 12460 all phecode
378.1 Strabismus (not specified as paralytic) Sense Organs 0.967 0.899 – 1.04 0.363 828 8130 all phecode
378.2 Nystagmus and other irregular eye movements Sense Organs 1.02 0.874 – 1.2 0.773 170 1686 all phecode
378.5 Paralytic strabismus Sense Organs 1.01 0.902 – 1.13 0.881 349 3437 all phecode
379 Other disorders of eye Sense Organs 0.992 0.962 – 1.02 0.603 5046 29999 all phecode
379.1 Scleritis and episcleritis Sense Organs 1.03 0.88 – 1.2 0.732 176 1743 all phecode
379.2 Disorders of vitreous body Sense Organs 0.983 0.948 – 1.02 0.359 3634 23186 all phecode
379.3 Aphakia and other disorders of lens Sense Organs 1.01 0.841 – 1.21 0.938 135 1258 all phecode
379.4 Anomalies of pupillary function Sense Organs 1.02 0.899 – 1.15 0.798 287 2833 all phecode
379.5 Disorders of iris and ciliary body Sense Organs 1.03 0.915 – 1.17 0.601 304 2948 all phecode
379.51 Pigmentary iris degeneration Sense Organs 0.835 0.66 – 1.06 0.132 77 731 all phecode
379.9 Pain, swelling or discharge of eye Sense Organs 1.04 0.976 – 1.1 0.232 1129 11130 all phecode
380 Disorders of external ear Sense Organs 0.934 0.893 – 0.976 0.00238 2242 20393 all phecode
380.1 Otitis externa Sense Organs 1.03 0.974 – 1.09 0.318 1469 14580 all phecode
380.4 Impacted cerumen Sense Organs 0.94 0.903 – 0.979 0.00301 2648 23557 all phecode
381 Otitis media and Eustachian tube disorders Sense Organs 1.01 0.981 – 1.05 0.423 4255 36417 all phecode
381.1 Otitis media Sense Organs 1.04 1 – 1.08 0.036 3079 29813 all phecode
381.11 Suppurative and unspecified otitis media Sense Organs 1.05 1.01 – 1.1 0.0124 2610 25602 all phecode
381.2 Eustachian tube disorders Sense Organs 0.975 0.928 – 1.02 0.304 1816 17827 all phecode
381.3 Mastoiditis & related conditions Sense Organs 1.16 0.981 – 1.37 0.0821 153 1530 all phecode
381.9 Otorrhea Sense Organs 1.1 0.985 – 1.22 0.0918 372 3713 all phecode
382 Otalgia Sense Organs 1.07 1.02 – 1.12 0.00625 1884 18673 all phecode
383 Otosclerosis Sense Organs 0.873 0.729 – 1.05 0.143 124 1240 all phecode
384 Other disorders of tympanic membrane Sense Organs 1.1 1 – 1.2 0.044 516 5156 all phecode
384.1 Myringitis Sense Organs 1.08 0.822 – 1.43 0.572 51 502 all phecode
384.4 Perforation of tympanic membrane Sense Organs 1.12 1.01 – 1.25 0.0286 403 4029 all phecode
385 Other disorders of middle ear and mastoid Sense Organs 1.01 0.91 – 1.11 0.897 432 4320 all phecode
385.3 Cholesteatoma Sense Organs 1.03 0.914 – 1.17 0.588 277 2770 all phecode
385.5
Tympanosclerosis and middle ear disease related
Tympanosclerosis and middle ear disease related to otitis media
 Sense Organs 0.894 0.738 – 1.08 0.247 118 1180 all phecode
386
Vertiginous syndromes and other disorders of
Vertiginous syndromes and other disorders of vestibular system
 Sense Organs 1.07 1.02 – 1.12 0.00811 1882 18186 all phecode
386.1 Meniere's disease Sense Organs 0.97 0.865 – 1.09 0.595 319 3156 all phecode
386.2 Peripheral or central vertigo Sense Organs 1.07 1.02 – 1.13 0.00757 1586 15423 all phecode
386.21 Central origin vertigo Sense Organs 1.06 1 – 1.13 0.042 1208 11844 all phecode
386.3 Labyrinthitis Sense Organs 1.05 0.999 – 1.11 0.0539 1482 14530 all phecode
386.9
Dizziness and giddiness (Light-headedness and
Dizziness and giddiness (Light-headedness and vertigo)
 Sense Organs 1.03 1.01 – 1.06 0.0137 6933 38286 all phecode
388 Other disorders of ear Sense Organs 1.01 0.949 – 1.09 0.67 960 9501 all phecode
389 Hearing loss Sense Organs 1.01 0.987 – 1.04 0.353 8182 38069 all phecode
389.1 Sensorineural hearing loss Sense Organs 0.978 0.946 – 1.01 0.197 4107 29258 all phecode
389.2 Conductive hearing loss Sense Organs 0.999 0.932 – 1.07 0.982 905 9042 all phecode
389.3 Degenerative and vascular disorders of ear Sense Organs 0.92 0.791 – 1.07 0.282 192 1808 all phecode
389.4 Tinnitus Sense Organs 0.976 0.935 – 1.02 0.279 2291 22130 all phecode
389.5 Disorders of acoustic nerve Sense Organs 1.06 0.885 – 1.28 0.515 124 1229 all phecode
394 Rheumatic disease of the heart valves Circulatory System 1.02 0.968 – 1.08 0.411 1458 13732 all phecode
394.1 Mitral valve stenosis and aortic valve stenosis Circulatory System 0.958 0.856 – 1.07 0.457 350 3415 all phecode
394.2 Mitral valve disease Circulatory System 1.03 0.936 – 1.14 0.539 462 4560 all phecode
394.3 Aortic valve disease Circulatory System 1.03 0.88 – 1.21 0.688 176 1691 all phecode
394.4 Acute rheumatic heart disease Circulatory System 1.15 0.873 – 1.5 0.326 55 546 all phecode
394.7 Disease of tricuspid valve Circulatory System 1.03 0.944 – 1.12 0.506 587 5739 all phecode
395 Heart valve disorders Circulatory System 1.03 0.993 – 1.06 0.115 3976 28748 all phecode
395.1 Nonrheumatic mitral valve disorders Circulatory System 1.01 0.966 – 1.06 0.642 2175 20441 all phecode
395.2 Nonrheumatic aortic valve disorders Circulatory System 1.02 0.974 – 1.07 0.384 2060 17194 all phecode
395.3 Nonrheumatic tricuspid valve disorders Circulatory System 1.02 0.926 – 1.11 0.742 493 4864 all phecode
395.4 Nonrheumatic pulmonary valve disorders Circulatory System 0.985 0.805 – 1.21 0.883 108 1080 all phecode
395.6 Heart valve replaced Circulatory System 1.02 0.957 – 1.08 0.582 1177 10833 all phecode
396 Abnormal heart sounds Circulatory System 1.02 0.991 – 1.05 0.174 4718 34395 all phecode
401 Hypertension Circulatory System 1.11 1.08 – 1.13 4.96e-21 23317 23367 all phecode
401.1 Essential hypertension Circulatory System 1.11 1.08 – 1.13 7.38e-21 23158 23364 all phecode
401.2 Hypertensive heart and/or renal disease Circulatory System 1.12 1.08 – 1.17 1.91e-08 3503 14616 all phecode
401.21 Hypertensive heart disease Circulatory System 1.09 1.02 – 1.17 0.0166 893 6607 all phecode
401.22 Hypertensive chronic kidney disease Circulatory System 1.13 1.08 – 1.18 1.13e-07 2584 13072 all phecode
401.3 Other hypertensive complications Circulatory System 1.09 1.05 – 1.14 4.87e-05 2679 15833 all phecode
411 Ischemic Heart Disease Circulatory System 1.1 1.07 – 1.13 1.03e-12 8807 30299 all phecode
411.1 Unstable angina (intermediate coronary syndrome) Circulatory System 1.09 1.01 – 1.16 0.0207 937 8574 all phecode
411.2 Myocardial infarction Circulatory System 1.13 1.09 – 1.17 1.9e-10 3594 21716 all phecode
411.3 Angina pectoris Circulatory System 1.09 1.05 – 1.14 4.83e-05 2485 18304 all phecode
411.4 Coronary atherosclerosis Circulatory System 1.09 1.06 – 1.12 1.4e-10 7555 27492 all phecode
411.41 Aneurysm and dissection of heart Circulatory System 1.16 0.977 – 1.37 0.0915 156 1529 all phecode
411.8
Other chronic ischemic heart disease
Other chronic ischemic heart disease, unspecified
 Circulatory System 1.1 1.07 – 1.14 4.96e-11 6331 25741 all phecode
411.9
Other acute and subacute forms of ischemic
Other acute and subacute forms of ischemic heart disease
 Circulatory System 1.06 0.96 – 1.17 0.243 442 4211 all phecode
414 Other forms of chronic heart disease Circulatory System 1.06 1.02 – 1.1 0.0057 3101 22616 all phecode
414.2 ASCVD Circulatory System 1.08 1 – 1.17 0.0488 718 6816 all phecode
415 Pulmonary heart disease Circulatory System 1.04 0.999 – 1.07 0.0539 3366 30208 all phecode
415.1 Acute pulmonary heart disease Circulatory System 1.04 0.996 – 1.1 0.0739 1912 19014 all phecode
415.11 Pulmonary embolism and infarction, acute Circulatory System 1.05 0.998 – 1.1 0.0585 1906 18953 all phecode
415.2 Chronic pulmonary heart disease Circulatory System 1.05 0.996 – 1.1 0.0727 1808 17605 all phecode
415.21 Primary pulmonary hypertension Circulatory System 1.03 0.948 – 1.11 0.526 706 7032 all phecode
416 Cardiomegaly Circulatory System 0.989 0.932 – 1.05 0.708 1254 12372 all phecode
418 Nonspecific chest pain Circulatory System 1.04 1.02 – 1.06 0.000205 12650 33952 all phecode
418.1 Precordial pain Circulatory System 1.06 1.01 – 1.12 0.0318 1471 13782 all phecode
420 Carditis Circulatory System 1.01 0.958 – 1.06 0.713 1588 15680 all phecode
420.1 Myocarditis Circulatory System 0.783 0.633 – 0.97 0.0249 97 958 all phecode
420.2 Pericarditis Circulatory System 1.03 0.957 – 1.1 0.458 842 8402 all phecode
420.21 Acute pericarditis Circulatory System 1.03 0.882 – 1.2 0.714 177 1764 all phecode
420.22 Chronic pericarditis Circulatory System 1.04 0.858 – 1.26 0.699 117 1153 all phecode
420.3 Endocarditis Circulatory System 1.02 0.946 – 1.1 0.607 764 7535 all phecode
425 Cardiomyopathy Circulatory System 1.02 0.97 – 1.06 0.512 2078 19881 all phecode
425.1 Primary/intrinsic cardiomyopathies Circulatory System 1.03 0.979 – 1.08 0.281 1989 19025 all phecode
425.11 Hypertrophic obstructive cardiomyopathy Circulatory System 0.981 0.855 – 1.13 0.791 208 2050 all phecode
425.12 Other hypertrophic cardiomyopathy Circulatory System 0.994 0.862 – 1.15 0.939 201 1992 all phecode
425.2 Secondary/extrinsic cardiomyopathies Circulatory System 0.948 0.844 – 1.07 0.37 317 3170 all phecode
425.8 Other cardiomyopathy Circulatory System 1 0.81 – 1.24 0.996 95 931 all phecode
426 Cardiac conduction disorders Circulatory System 1.01 0.992 – 1.04 0.211 12327 25440 all phecode
426.2 Atrioventricular [AV] block Circulatory System 1 0.951 – 1.05 0.988 1903 11501 all phecode
426.21 First degree AV block Circulatory System 0.989 0.932 – 1.05 0.713 1313 8899 all phecode
426.22 Mobitz II AV block Circulatory System 0.93 0.718 – 1.21 0.583 64 553 all phecode
426.23 Second degree AV block Circulatory System 0.988 0.857 – 1.14 0.867 216 1925 all phecode
426.24 Atrioventricular block, complete Circulatory System 1.01 0.92 – 1.12 0.777 461 3823 all phecode
426.25 Other heart block Circulatory System 0.951 0.822 – 1.1 0.504 203 1803 all phecode
426.3 Bundle branch block Circulatory System 1.03 0.983 – 1.08 0.22 2306 13999 all phecode
426.31 Right bundle branch block Circulatory System 1.02 0.966 – 1.08 0.46 1423 10758 all phecode
426.32 Left bundle branch block Circulatory System 1.04 0.974 – 1.11 0.235 969 8110 all phecode
426.4 Anomalous atrioventricular excitation Circulatory System 1.02 0.81 – 1.29 0.856 82 820 all phecode
426.7 Abnormal electrocardiogram [ECG] [EKG] Circulatory System 1.01 0.988 – 1.04 0.306 10577 25186 all phecode
426.8 Other cardiac conduction disorders Circulatory System 1 0.923 – 1.08 0.999 679 6650 all phecode
426.9 Cardiac pacemaker/device in situ Circulatory System 0.981 0.932 – 1.03 0.47 1754 11536 all phecode
426.91 Cardiac pacemaker in situ Circulatory System 0.981 0.922 – 1.04 0.551 1171 8184 all phecode
426.92 Cardiac defibrillator in situ Circulatory System 0.97 0.903 – 1.04 0.416 846 7320 all phecode
427 Cardiac dysrhythmias Circulatory System 1.01 0.992 – 1.03 0.23 17397 25735 all phecode
427.1 Paroxysmal tachycardia, unspecified Circulatory System 1 0.958 – 1.04 0.991 2474 18178 all phecode
427.11 Paroxysmal supraventricular tachycardia Circulatory System 1.01 0.963 – 1.07 0.594 1595 14293 all phecode
427.12 Paroxysmal ventricular tachycardia Circulatory System 0.975 0.917 – 1.04 0.417 1181 9915 all phecode
427.2 Atrial fibrillation and flutter Circulatory System 1.01 0.981 – 1.05 0.411 5313 18688 all phecode
427.21 Atrial fibrillation Circulatory System 1.01 0.977 – 1.04 0.568 5188 18409 all phecode
427.22 Atrial flutter Circulatory System 0.974 0.924 – 1.03 0.331 1693 11042 all phecode
427.3 Other specified cardiac dysrhythmias Circulatory System 1.02 0.991 – 1.04 0.196 8688 25552 all phecode
427.4 Cardiac arrest and ventricular fibrillation Circulatory System 1 0.916 – 1.1 0.973 536 5233 all phecode
427.41 Ventricular fibrillation and flutter Circulatory System 0.883 0.766 – 1.02 0.0879 216 2118 all phecode
427.42 Cardiac arrest Circulatory System 1.07 0.965 – 1.18 0.202 410 4034 all phecode
427.5 Arrhythmia (cardiac) NOS Circulatory System 1 0.975 – 1.03 0.842 6905 25457 all phecode
427.6 Premature beats Circulatory System 0.988 0.945 – 1.03 0.6 2359 16248 all phecode
427.61 Supraventricular premature beats Circulatory System 1.01 0.936 – 1.1 0.728 670 6287 all phecode
427.7 Tachycardia NOS Circulatory System 1.03 0.997 – 1.06 0.0801 5124 25531 all phecode
427.8 Sinoatrial node dysfunction (Bradycardia) Circulatory System 1.02 0.955 – 1.1 0.511 912 7501 all phecode
427.9 Palpitations Circulatory System 0.976 0.944 – 1.01 0.142 4430 24505 all phecode
428 Congestive heart failure; nonhypertensive Circulatory System 1.05 1.01 – 1.08 0.00606 4300 23663 all phecode
428.1 Congestive heart failure (CHF) NOS Circulatory System 1.05 1.02 – 1.09 0.00355 3756 22446 all phecode
428.2 Heart failure NOS Circulatory System 1.05 1.01 – 1.09 0.00689 3701 21722 all phecode
428.3
Heart failure with reduced EF [Systolic or
Heart failure with reduced EF [Systolic or combined heart failure]
 Circulatory System 1.03 0.977 – 1.08 0.301 1765 14476 all phecode
428.4
Heart failure with preserved EF [Diastolic
Heart failure with preserved EF [Diastolic heart failure]
 Circulatory System 1.06 1.01 – 1.12 0.0267 1648 13395 all phecode
429
Ill-defined descriptions and complications of
Ill-defined descriptions and complications of heart disease
 Circulatory System 1.02 0.995 – 1.04 0.136 12635 32504 all phecode
429.1 Heart transplant/surgery Circulatory System 1.03 0.971 – 1.1 0.315 1219 11696 all phecode
429.2 Abnormal function study of cardiovascular system Circulatory System 1.03 0.998 – 1.06 0.0641 6322 29232 all phecode
429.3 Symptoms involving cardiovascular system Circulatory System 1.02 0.994 – 1.04 0.138 9650 32421 all phecode
429.9 Cardiac complications, not elsewhere classified Circulatory System 0.973 0.9 – 1.05 0.486 723 7072 all phecode
430 Intracranial hemorrhage Circulatory System 1 0.929 – 1.08 0.991 789 7842 all phecode
430.1 Subarachnoid hemorrhage Circulatory System 0.917 0.806 – 1.04 0.184 261 2610 all phecode
430.2 Intracerebral hemorrhage Circulatory System 1.07 0.957 – 1.19 0.241 368 3671 all phecode
430.3 Subdural hemorrhage Circulatory System 1 0.885 – 1.14 0.956 272 2680 all phecode
433 Cerebrovascular disease Circulatory System 1.06 1.03 – 1.09 0.000197 5463 32242 all phecode
433.1 Occlusion and stenosis of precerebral arteries Circulatory System 1.06 1.01 – 1.12 0.0118 1978 16212 all phecode
433.11
Occlusion of cerebral arteries, with cerebral
Occlusion of cerebral arteries, with cerebral infarction
 Circulatory System 1.06 0.932 – 1.21 0.371 260 2517 all phecode
433.12 Cerebral atherosclerosis Circulatory System 1.09 0.876 – 1.37 0.431 80 789 all phecode
433.2 Occlusion of cerebral arteries Circulatory System 1.03 0.987 – 1.07 0.172 2437 21732 all phecode
433.21
Cerebral artery occlusion, with cerebral
Cerebral artery occlusion, with cerebral infarction
 Circulatory System 1.03 0.99 – 1.08 0.137 2357 21103 all phecode
433.3 Cerebral ischemia Circulatory System 1.03 0.986 – 1.07 0.209 2780 22868 all phecode
433.31 Transient cerebral ischemia Circulatory System 1.02 0.98 – 1.07 0.289 2409 20762 all phecode
433.5 Cerebral aneurysm Circulatory System 1.11 1.01 – 1.22 0.0312 474 4724 all phecode
433.6 Acute, but ill-defined cerebrovascular disease Circulatory System 0.977 0.887 – 1.08 0.639 464 4518 all phecode
433.8 Late effects of cerebrovascular disease Circulatory System 0.945 0.873 – 1.02 0.17 695 6822 all phecode
440 Atherosclerosis Circulatory System 1.09 1.05 – 1.14 3.1e-05 2477 19724 all phecode
440.1 Atherosclerosis of renal artery Circulatory System 1.13 0.982 – 1.29 0.088 231 2291 all phecode
440.2 Atherosclerosis of the extremities Circulatory System 1.11 1.05 – 1.17 0.000135 1516 13532 all phecode
440.21
Atherosclerosis of native arteries of the
Atherosclerosis of native arteries of the extremities with ulceration or gangrene
 Circulatory System 1.09 0.961 – 1.23 0.183 274 2669 all phecode
440.22
Atherosclerosis of native arteries of the
Atherosclerosis of native arteries of the extremities with intermittent claudication
 Circulatory System 1.11 1.04 – 1.18 0.00198 1040 9647 all phecode
440.9 Atherosclerosis of aorta Circulatory System 1.08 1.01 – 1.16 0.032 846 8124 all phecode
441 Vascular insufficiency of intestine Circulatory System 1.14 1.04 – 1.25 0.00487 515 5115 all phecode
441.1 Acute vascular insufficiency of intestine Circulatory System 1.06 0.927 – 1.21 0.398 240 2387 all phecode
441.2 Chronic vascular insufficiency of intestine Circulatory System 1.28 1.08 – 1.52 0.00424 154 1536 all phecode
442 Other aneurysm Circulatory System 1.05 1 – 1.09 0.0316 2779 21466 all phecode
442.1 Aortic aneurysm Circulatory System 1.05 1.01 – 1.1 0.0285 2054 16492 all phecode
442.11 Abdominal aortic aneurysm Circulatory System 1.08 1.01 – 1.15 0.0155 1189 10558 all phecode
442.2 Aneurysm of iliac artery Circulatory System 1.11 0.961 – 1.28 0.156 202 2002 all phecode
442.3 Aneurysm of artery of lower extremity Circulatory System 1.07 0.918 – 1.25 0.386 179 1765 all phecode
442.4 Arterial dissection Circulatory System 1.09 0.937 – 1.26 0.271 184 1840 all phecode
442.8 Aneurysm of other specified artery Circulatory System 1 0.902 – 1.11 0.972 399 3978 all phecode
443 Peripheral vascular disease Circulatory System 1.07 1.03 – 1.11 0.000622 3086 24814 all phecode
443.1 Raynaud's syndrome Circulatory System 1.01 0.937 – 1.09 0.788 742 7390 all phecode
443.7
Peripheral angiopathy in diseases classified
Peripheral angiopathy in diseases classified elsewhere
 Circulatory System 1.09 0.949 – 1.26 0.215 220 2087 all phecode
443.8 Other specified peripheral vascular diseases Circulatory System 1.08 1.04 – 1.13 0.000194 2557 21985 all phecode
443.9 Peripheral vascular disease, unspecified Circulatory System 1.09 1.04 – 1.14 0.000159 2341 18862 all phecode
444 Arterial embolism and thrombosis Circulatory System 1.08 1 – 1.16 0.0366 848 8423 all phecode
444.1
Arterial embolism and thrombosis of lower
Arterial embolism and thrombosis of lower extremity artery
 Circulatory System 1.06 0.946 – 1.2 0.303 313 3099 all phecode
444.2 Embolism and thrombosis of abdominal aorta Circulatory System 1.09 0.926 – 1.28 0.302 155 1548 all phecode
446 Polyarteritis nodosa and allied conditions Circulatory System 1.02 0.923 – 1.12 0.737 460 4559 all phecode
446.4 Wegener's granulomatosis Circulatory System 0.91 0.747 – 1.11 0.346 109 1075 all phecode
446.5 Giant cell arteritis Circulatory System 1.21 0.959 – 1.52 0.109 79 749 all phecode
446.9 Arteritis NOS Circulatory System 1.06 0.939 – 1.2 0.344 289 2876 all phecode
447 Other disorders of arteries and arterioles Circulatory System 1.06 1.01 – 1.1 0.00926 2647 22765 all phecode
447.1 Stricture of artery Circulatory System 1.13 1.03 – 1.24 0.0105 523 5163 all phecode
447.7 Aortic ectasia Circulatory System 1.02 0.947 – 1.1 0.611 804 7938 all phecode
448 Disease of capillaries Circulatory System 0.937 0.884 – 0.994 0.0308 1237 12127 all phecode
450 Noninfectious disorders of lymphatic channels Circulatory System 1 0.956 – 1.05 0.996 2104 20985 all phecode
451 Phlebitis and thrombophlebitis Circulatory System 0.99 0.917 – 1.07 0.806 738 7355 all phecode
451.2
Phlebitis and thrombophlebitis of lower
Phlebitis and thrombophlebitis of lower extremities
 Circulatory System 0.929 0.813 – 1.06 0.284 244 2437 all phecode
452 Other venous embolism and thrombosis Circulatory System 1.01 0.981 – 1.04 0.478 4957 29867 all phecode
452.1 Iatrogenic pulmonary embolism and infarction Circulatory System 1.04 0.911 – 1.18 0.598 276 2747 all phecode
452.2 Deep vein thrombosis [DVT] Circulatory System 1.01 0.977 – 1.05 0.482 3260 26940 all phecode
452.8 Postphlebitic syndrome Circulatory System 1.12 0.945 – 1.32 0.197 154 1529 all phecode
453 Chronic venous hypertension Circulatory System 1.06 0.922 – 1.23 0.394 220 2168 all phecode
454 Varicose veins Circulatory System 0.977 0.939 – 1.02 0.256 2827 24555 all phecode
454.1 Varicose veins of lower extremity Circulatory System 0.98 0.94 – 1.02 0.355 2469 21426 all phecode
454.11 Varicose veins of lower extremity, symptomtic Circulatory System 0.99 0.939 – 1.04 0.713 1565 15056 all phecode
455 Hemorrhoids Circulatory System 0.98 0.952 – 1.01 0.18 5799 29818 all phecode
456 Chronic venous insufficiency [CVI] Circulatory System 0.984 0.947 – 1.02 0.392 3097 24898 all phecode
457
Encounter for long-term (current) use of
Encounter for long-term (current) use of anticoagulants, antithrombotics, aspirin
 Circulatory System 1.04 0.994 – 1.09 0.0843 2095 15309 all phecode
457.2
Encounter for long-term (current) use of
Encounter for long-term (current) use of antiplatelets/antithrombotics
 Circulatory System 1.01 0.903 – 1.14 0.826 324 3221 all phecode
457.3 Encounter for long-term (current) use of aspirin Circulatory System 1.05 0.998 – 1.1 0.0592 1973 14689 all phecode
458 Hypotension Circulatory System 1.04 1.01 – 1.07 0.00668 5091 32185 all phecode
458.1 Orthostatic hypotension Circulatory System 1.03 0.969 – 1.09 0.378 1344 12938 all phecode
458.2 Iatrogenic hypotension Circulatory System 1.06 0.999 – 1.13 0.0557 1109 11012 all phecode
458.9 Hypotension NOS Circulatory System 1.05 1.02 – 1.08 0.00287 4618 31186 all phecode
459 Other disorders of circulatory system Circulatory System 1.04 1.01 – 1.06 0.00481 7825 34792 all phecode
459.1 Hemorrhage NOS Circulatory System 0.986 0.918 – 1.06 0.709 834 8215 all phecode
459.7 Blood vessel replaced Circulatory System 1.03 0.969 – 1.09 0.376 1305 13023 all phecode
459.9 Circulatory disease NEC Circulatory System 1.04 1.02 – 1.07 0.00149 6706 33592 all phecode
464 Acute sinusitis Respiratory 0.965 0.936 – 0.996 0.0263 4792 32137 all phecode
465
Acute upper respiratory infections of multiple
Acute upper respiratory infections of multiple or unspecified sites
 Respiratory 0.964 0.942 – 0.987 0.00189 9601 35915 all phecode
465.2 Acute pharyngitis Respiratory 0.977 0.948 – 1.01 0.123 5310 32365 all phecode
465.4 Acute laryngitis and tracheitis Respiratory 0.932 0.843 – 1.03 0.167 443 4428 all phecode
470 Septal Deviations/Turbinate Hypertrophy Respiratory 1.01 0.963 – 1.06 0.643 1797 17640 all phecode
471 Nasal polyps Respiratory 0.926 0.851 – 1.01 0.0753 592 5881 all phecode
472 Chronic pharyngitis and nasopharyngitis Respiratory 1.03 0.978 – 1.08 0.287 1797 16986 all phecode
473 Diseases of the larynx and vocal cords Respiratory 1 0.967 – 1.04 0.812 2983 25244 all phecode
473.1 Chronic laryngitis Respiratory 1.2 0.944 – 1.52 0.138 68 674 all phecode
473.3 Paralysis/spasm of vocal cords or larynx Respiratory 1.05 0.964 – 1.14 0.277 628 6254 all phecode
473.4 Voice disturbance Respiratory 0.997 0.955 – 1.04 0.903 2336 21975 all phecode
474 Acute and chronic tonsillitis Respiratory 0.981 0.914 – 1.05 0.594 880 7892 all phecode
474.1 Acute tonsillitis Respiratory 0.952 0.85 – 1.07 0.399 335 3181 all phecode
474.2 Chronic tonsillitis and adenoiditis Respiratory 0.996 0.921 – 1.08 0.922 700 6445 all phecode
475 Chronic sinusitis Respiratory 1 0.97 – 1.04 0.898 4378 27891 all phecode
475.9 Postnasal drip Respiratory 0.963 0.899 – 1.03 0.287 922 9017 all phecode
476 Allergic rhinitis Respiratory 0.998 0.977 – 1.02 0.849 12687 28117 all phecode
477 Epistaxis or throat hemorrhage Respiratory 0.999 0.94 – 1.06 0.979 1150 11318 all phecode
478 Throat pain Respiratory 1.04 0.937 – 1.15 0.484 426 4195 all phecode
479 Other upper respiratory disease Respiratory 1.03 1 – 1.06 0.0515 5627 28048 all phecode
480 Pneumonia Respiratory 1.03 0.998 – 1.06 0.0694 5947 37034 all phecode
480.1 Bacterial pneumonia Respiratory 0.948 0.891 – 1.01 0.087 1155 11495 all phecode
480.11 Pneumococcal pneumonia Respiratory 0.925 0.846 – 1.01 0.0823 568 5644 all phecode
480.12 Pseudomonal pneumonia Respiratory 0.909 0.767 – 1.08 0.276 153 1523 all phecode
480.13 MRSA pneumonia Respiratory 1 0.829 – 1.21 0.974 117 1165 all phecode
480.2 Viral pneumonia Respiratory 1.03 0.896 – 1.19 0.647 202 1992 all phecode
480.3 Pneumonia due to fungus (mycoses) Respiratory 0.945 0.8 – 1.12 0.503 159 1590 all phecode
480.5 Bronchopneumonia and lung abscess Respiratory 0.94 0.788 – 1.12 0.487 135 1312 all phecode
481 Influenza Respiratory 1.02 0.965 – 1.08 0.476 1355 13284 all phecode
483 Acute bronchitis and bronchiolitis Respiratory 0.987 0.952 – 1.02 0.483 3412 29871 all phecode
495 Asthma Respiratory 1.07 1.04 – 1.09 2.28e-07 8671 33569 all phecode
495.1 Chronic obstructive asthma Respiratory 1.02 0.918 – 1.13 0.709 397 3925 all phecode
495.11 Chronic obstructive asthma with exacerbation Respiratory 0.947 0.746 – 1.2 0.655 81 802 all phecode
495.2 Asthma with exacerbation Respiratory 1.01 0.959 – 1.06 0.706 1629 16033 all phecode
496 Chronic airway obstruction Respiratory 1.14 1.1 – 1.17 9.92e-17 5343 28343 all phecode
496.1 Emphysema Respiratory 1.13 1.08 – 1.19 6.06e-08 2134 19414 all phecode
496.2 Chronic bronchitis Respiratory 1.16 1.12 – 1.2 4.26e-18 4128 26624 all phecode
496.21 Obstructive chronic bronchitis Respiratory 1.16 1.12 – 1.21 2.19e-17 3747 25467 all phecode
496.3 Bronchiectasis Respiratory 0.999 0.913 – 1.09 0.981 549 5453 all phecode
497 Bronchitis Respiratory 0.995 0.949 – 1.04 0.839 1946 18824 all phecode
498 Acute bronchospasm Respiratory 0.979 0.891 – 1.08 0.656 496 4943 all phecode
499 Cystic fibrosis Respiratory 1.02 0.861 – 1.2 0.846 151 1510 all phecode
500 Lung disease due to external agents Respiratory 1.05 0.964 – 1.15 0.249 557 5551 all phecode
500.1 Extrinsic allergic alveolitis Respiratory 1.27 1.02 – 1.58 0.031 92 920 all phecode
500.2 Pneumoconiosis Respiratory 0.943 0.752 – 1.18 0.61 78 764 all phecode
501 Pneumonitis due to inhalation of food or vomitus Respiratory 0.997 0.918 – 1.08 0.953 634 6225 all phecode
502 Postinflammatory pulmonary fibrosis Respiratory 1.06 0.986 – 1.14 0.116 815 8076 all phecode
503 Pulmonary congestion and hypostasis Respiratory 0.953 0.886 – 1.02 0.189 835 8243 all phecode
504 Other alveolar and parietoalveolar pneumonopathy Respiratory 1.04 0.952 – 1.13 0.402 595 5878 all phecode
504.1 Idiopathic fibrosing alveolitis Respiratory 1.04 0.925 – 1.17 0.497 311 3084 all phecode
505 Other pulmonary inflamation or edema Respiratory 1.03 0.975 – 1.08 0.325 1638 15749 all phecode
506 Empyema and pneumothorax Respiratory 1.04 1 – 1.09 0.0276 2894 25235 all phecode
507 Pleurisy; pleural effusion Respiratory 1.02 0.981 – 1.06 0.321 2916 26208 all phecode
508
Pulmonary collapse; interstitial and
Pulmonary collapse; interstitial and compensatory emphysema
 Respiratory 1.02 0.982 – 1.07 0.267 2382 22588 all phecode
509 Respiratory failure, insufficiency, arrest Respiratory 1.05 1.02 – 1.09 0.00396 4032 29477 all phecode
509.1 Respiratory failure Respiratory 1.04 0.996 – 1.09 0.073 1937 18949 all phecode
509.2 Respiratory insufficiency Respiratory 1.02 0.962 – 1.09 0.484 1174 11679 all phecode
509.3
Pulmonary insufficiency or respiratory failure
Pulmonary insufficiency or respiratory failure following trauma and surgery
 Respiratory 1.05 1 – 1.11 0.0419 1689 16489 all phecode
509.8
Dependence on respirator [Ventilator] or
Dependence on respirator [Ventilator] or supplemental oxygen
 Respiratory 1.03 0.984 – 1.09 0.184 1741 17249 all phecode
510 Other diseases of lung Respiratory 1.03 0.996 – 1.06 0.0871 5503 35907 all phecode
510.2 Lung transplant Respiratory 1.02 0.874 – 1.19 0.798 176 1757 all phecode
512 Other symptoms of respiratory system Respiratory 1.01 0.994 – 1.03 0.176 18621 28154 all phecode
512.1 Wheezing Respiratory 1.02 0.961 – 1.07 0.583 1409 13516 all phecode
512.2 Painful respiration Respiratory 1.07 1.03 – 1.12 0.00204 2309 21263 all phecode
512.3 Abnormal chest sounds Respiratory 1.01 0.898 – 1.14 0.847 291 2845 all phecode
512.7 Shortness of breath Respiratory 1.05 1.02 – 1.07 0.000133 10034 28081 all phecode
512.8 Cough Respiratory 0.999 0.975 – 1.02 0.915 9501 28148 all phecode
512.9 Other dyspnea Respiratory 1.03 1 – 1.05 0.0194 10804 28104 all phecode
513 Respiratory abnormalities Respiratory 1.03 1.01 – 1.05 0.0134 12932 33822 all phecode
513.3 Hypoventilation Respiratory 1.02 0.95 – 1.09 0.582 880 8646 all phecode
513.31 Apnea Respiratory 1.04 0.942 – 1.14 0.459 462 4607 all phecode
513.32 Orthopnea Respiratory 1.08 0.94 – 1.25 0.269 220 2160 all phecode
513.4 Hyperventilation Respiratory 1.12 1.02 – 1.23 0.0164 515 5124 all phecode
513.8 Disorders of diaphragm Respiratory 0.949 0.832 – 1.08 0.433 258 2557 all phecode
514 Abnormal findings examination of lungs Respiratory 1.01 0.985 – 1.04 0.347 5365 34834 all phecode
514.1
Abnormal results of function study of pulmonary
Abnormal results of function study of pulmonary system
 Respiratory 1.12 0.979 – 1.28 0.0983 258 2580 all phecode
514.2 Solitary pulmonary nodule Respiratory 1.02 0.978 – 1.06 0.409 3018 27338 all phecode
516 Abnormal sputum Respiratory 1.02 0.943 – 1.1 0.652 735 7332 all phecode
516.1 Hemoptysis Respiratory 1.02 0.939 – 1.11 0.622 611 6080 all phecode
519
Other diseases of respiratory system, not
Other diseases of respiratory system, not elsewhere classified
 Respiratory 1.03 1 – 1.05 0.0541 6458 39057 all phecode
519.1 Tracheostomy complications Respiratory 1.1 0.951 – 1.26 0.205 214 2136 all phecode
519.2 Respiratory complications Respiratory 1.13 1.02 – 1.25 0.015 445 4430 all phecode
519.8 Other diseases of respiratory system, NEC Respiratory 1 0.952 – 1.06 0.898 1588 15787 all phecode
519.9
Symptoms involving respiratory system and other
Symptoms involving respiratory system and other chest symptoms
 Respiratory 1.03 1 – 1.07 0.0378 4706 34489 all phecode
520 Disorders of tooth development Digestive 1.07 0.963 – 1.2 0.199 369 3690 all phecode
520.1 Hereditary disturbances in tooth structure Digestive 1.1 0.931 – 1.3 0.267 165 1642 all phecode
520.2 Disturbances in tooth eruption Digestive 1.08 0.935 – 1.24 0.306 218 2172 all phecode
521 Diseases of hard tissues of teeth Digestive 1.13 1.06 – 1.22 0.000367 898 8954 all phecode
521.1 Dental caries Digestive 1.15 1.07 – 1.23 0.00022 837 8349 all phecode
521.2 Dental abrasion, erosion and attrition Digestive 1.01 0.755 – 1.34 0.972 52 510 all phecode
522 Diseases of pulp and periapical tissues Digestive 1.1 1.01 – 1.2 0.0364 535 5340 all phecode
522.5 Periapical abscess Digestive 1.09 0.986 – 1.2 0.0937 459 4583 all phecode
523 Gingival and periodontal diseases Digestive 1.07 0.989 – 1.16 0.0932 718 7180 all phecode
523.1 Gingivitis Digestive 0.87 0.728 – 1.04 0.125 142 1418 all phecode
523.3 Periodontitis (acute or chronic) Digestive 1.08 0.971 – 1.2 0.152 364 3636 all phecode
523.31 Acute periodontitis Digestive 1.06 0.94 – 1.19 0.359 311 3109 all phecode
523.32 Chronic periodontitis Digestive 1.1 0.912 – 1.32 0.327 122 1204 all phecode
524 Dentofacial anomalies, including malocclusion Digestive 0.884 0.793 – 0.985 0.0249 363 3630 all phecode
524.3 Anomalies of tooth position/malocclusion Digestive 0.922 0.803 – 1.06 0.251 220 2200 all phecode
525
Other diseases of the teeth and supporting
Other diseases of the teeth and supporting structures
 Digestive 1.06 0.991 – 1.13 0.0942 1039 10382 all phecode
525.1 Loss of teeth or edentulism Digestive 1.04 0.931 – 1.16 0.507 374 3731 all phecode
526 Diseases of the jaws Digestive 0.991 0.952 – 1.03 0.655 2680 26455 all phecode
526.1 Cysts of the jaws Digestive 0.946 0.829 – 1.08 0.413 247 2470 all phecode
526.3 Anomalies of jaw size/symmetry Digestive 0.933 0.817 – 1.07 0.305 241 2383 all phecode
526.4 Temporomandibular joint disorders Digestive 1.02 0.964 – 1.07 0.541 1504 15025 all phecode
526.41 Temporomandibular joint disorder, unspecified Digestive 1.02 0.962 – 1.08 0.489 1187 11858 all phecode
526.42 Arthralgia/ankylosis of temporomandibular joint Digestive 0.993 0.92 – 1.07 0.849 741 7400 all phecode
526.5 Inflammatory conditions of jaw Digestive 0.98 0.867 – 1.11 0.754 287 2864 all phecode
526.8 Exostosis of jaw Digestive 0.843 0.641 – 1.11 0.222 53 521 all phecode
526.9 Jaw disease NOS Digestive 0.972 0.884 – 1.07 0.568 487 4867 all phecode
527 Diseases of the salivary glands Digestive 0.99 0.942 – 1.04 0.684 1781 17771 all phecode
527.1 Hypertrophy of salivary gland Digestive 1.03 0.787 – 1.34 0.851 58 579 all phecode
527.2 Sialoadenitis Digestive 0.875 0.789 – 0.971 0.0122 394 3936 all phecode
527.7 Disturbance of salivary secretion Digestive 1 0.937 – 1.07 0.952 952 9481 all phecode
527.8 Other specified diseases of the salivary glands Digestive 1.1 0.969 – 1.26 0.137 254 2540 all phecode
528
Diseases of the oral soft tissues, excluding
Diseases of the oral soft tissues, excluding lesions specific for gingiva and tongue
 Digestive 0.969 0.93 – 1.01 0.127 2643 26197 all phecode
528.1 Stomatitis and mucositis Digestive 0.946 0.873 – 1.03 0.175 668 6657 all phecode
528.11 Stomatitis and mucositis (ulcerative) Digestive 0.991 0.858 – 1.14 0.899 211 2110 all phecode
528.12 Oral aphthae Digestive 0.984 0.855 – 1.13 0.824 215 2137 all phecode
528.3 Cellulitis and abscess of oral soft tissues Digestive 0.962 0.839 – 1.1 0.574 235 2338 all phecode
528.4 Cysts of oral soft tissues Digestive 1.03 0.859 – 1.24 0.741 124 1229 all phecode
528.41 Cyst of the salivary gland Digestive 0.965 0.765 – 1.22 0.767 77 760 all phecode
528.5 Diseases of lips Digestive 0.888 0.806 – 0.979 0.017 462 4602 all phecode
528.6 Leukoplakia of oral mucosa Digestive 0.902 0.757 – 1.07 0.244 137 1370 all phecode
528.7 Sialolithiasis Digestive 0.949 0.808 – 1.11 0.522 163 1623 all phecode
529 Diseases and other conditions of the tongue Digestive 0.997 0.921 – 1.08 0.933 690 6878 all phecode
529.1 Glossitis Digestive 1.09 0.908 – 1.3 0.367 129 1281 all phecode
529.6 Glossodynia Digestive 0.988 0.841 – 1.16 0.886 168 1652 all phecode
530 Diseases of esophagus Digestive 1.1 1.08 – 1.12 4.87e-22 17081 27931 all phecode
530.1 Esophagitis, GERD and related diseases Digestive 1.11 1.08 – 1.13 5.63e-23 16572 27931 all phecode
530.11 GERD Digestive 1.11 1.09 – 1.13 1.79e-24 16143 27929 all phecode
530.12 Ulcer of esophagus Digestive 1.12 1.01 – 1.24 0.0317 400 3983 all phecode
530.13 Barrett's esophagus Digestive 1.11 1.03 – 1.2 0.0081 762 7584 all phecode
530.14 Reflux esophagitis Digestive 1.12 1.07 – 1.18 3.18e-06 1900 17495 all phecode
530.15 Eosinophilic esophagitis Digestive 1.1 0.95 – 1.26 0.209 221 2210 all phecode
530.2 Esophageal bleeding (varices/hemorrhage) Digestive 1.06 0.978 – 1.15 0.154 651 6473 all phecode
530.3 Stricture and stenosis of esophagus Digestive 1.1 1.03 – 1.18 0.00801 911 8971 all phecode
530.5 Disorders of esophageal motility Digestive 1.06 0.968 – 1.16 0.209 548 5432 all phecode
530.6 Diverticulum of esophagus, acquired Digestive 0.983 0.819 – 1.18 0.85 129 1265 all phecode
530.7 Gastroesophageal laceration-hemorrhage syndrome Digestive 1.08 0.867 – 1.35 0.49 82 812 all phecode
530.9 Heartburn Digestive 1.07 1.01 – 1.13 0.0141 1519 14928 all phecode
531 Peptic ulcer (excl. esophageal) Digestive 1.06 1.01 – 1.11 0.0183 2073 20617 all phecode
531.1 Hemorrhage from gastrointestinal ulcer Digestive 0.979 0.882 – 1.09 0.693 391 3883 all phecode
531.2 Gastric ulcer Digestive 1.03 0.974 – 1.1 0.269 1201 11970 all phecode
531.3 Duodenal ulcer Digestive 1.06 0.96 – 1.16 0.261 467 4640 all phecode
531.4 Peptic ulcer, site unspecified Digestive 1.07 0.997 – 1.15 0.0606 804 8018 all phecode
531.5 Gastrojejunal ulcer Digestive 0.98 0.831 – 1.16 0.809 150 1500 all phecode
532 Dysphagia Digestive 1.09 1.06 – 1.13 3.57e-09 5585 26852 all phecode
535 Gastritis and duodenitis Digestive 1.07 1.03 – 1.11 0.000683 2799 27335 all phecode
535.1 Acute gastritis Digestive 1.03 0.97 – 1.1 0.331 1178 11750 all phecode
535.2 Atrophic gastritis Digestive 1.09 0.978 – 1.22 0.116 344 3413 all phecode
535.6 Duodenitis Digestive 1.1 0.981 – 1.23 0.102 334 3337 all phecode
535.8 Other specified gastritis Digestive 1.05 0.966 – 1.14 0.254 638 6354 all phecode
535.9 Gastritis and duodenitis, NOS Digestive 1.06 1 – 1.13 0.0496 1255 12511 all phecode
536 Disorders of function of stomach Digestive 1.05 1.01 – 1.09 0.0215 2911 27685 all phecode
536.3 Gastroparesis Digestive 1.14 1.05 – 1.23 0.00115 706 6901 all phecode
536.7
Complications of gastrostomy, colostomy and
Complications of gastrostomy, colostomy and enterostomy
 Digestive 1 0.904 – 1.12 0.935 407 4059 all phecode
536.8
Dyspepsia and other specified disorders of
Dyspepsia and other specified disorders of function of stomach
 Digestive 1.03 0.983 – 1.08 0.227 2150 21094 all phecode
537 Other disorders of stomach and duodenum Digestive 1.07 1.03 – 1.11 0.000653 3183 30048 all phecode
537.1 Lesions of stomach and duodenum Digestive 1.23 1.05 – 1.44 0.00934 173 1725 all phecode
539 Bariatric surgery Digestive 1.07 1.01 – 1.13 0.0168 1509 15074 all phecode
540 Appendiceal conditions Digestive 1.01 0.923 – 1.11 0.787 495 4948 all phecode
540.1 Appendicitis Digestive 1.02 0.927 – 1.13 0.644 425 4239 all phecode
540.11 Acute appendicitis Digestive 1 0.9 – 1.12 0.938 353 3511 all phecode
550 Abdominal hernia Digestive 1.04 1.01 – 1.06 0.00707 6768 37731 all phecode
550.1 Inguinal hernia Digestive 0.963 0.916 – 1.01 0.144 1744 16488 all phecode
550.2 Diaphragmatic hernia Digestive 1.06 1.02 – 1.1 0.0033 2817 25849 all phecode
550.3 Femoral hernia Digestive 1.11 0.924 – 1.32 0.272 131 1291 all phecode
550.4 Umbilical hernia Digestive 0.999 0.943 – 1.06 0.972 1313 13110 all phecode
550.5 Ventral hernia Digestive 1.06 1.02 – 1.11 0.00675 2241 22163 all phecode
550.6 Incisional hernia Digestive 0.993 0.938 – 1.05 0.82 1313 13111 all phecode
555
Inflammatory bowel disease and other
Inflammatory bowel disease and other gastroenteritis and colitis
 Digestive 1.06 1.01 – 1.12 0.0211 1536 15153 all phecode
555.1 Regional enteritis Digestive 1.04 0.967 – 1.11 0.312 919 9095 all phecode
555.2 Ulcerative colitis Digestive 1.08 1.01 – 1.16 0.0267 937 9315 all phecode
555.21 Ulcerative colitis (chronic) Digestive 1.06 0.967 – 1.16 0.217 537 5315 all phecode
556 Ulceration of the lower GI tract Digestive 1.09 1.01 – 1.19 0.0312 632 6267 all phecode
556.1 Ulceration of intestine Digestive 1.13 1.03 – 1.23 0.0071 551 5451 all phecode
556.11
Angiodysplasia of intestine (without mention of
Angiodysplasia of intestine (without mention of hemorrhage)
 Digestive 1 0.868 – 1.15 0.992 214 2093 all phecode
557 Intestinal malabsorption (non-celiac) Digestive 1.06 1.01 – 1.11 0.0268 1716 16490 all phecode
557.1 Celiac disease Digestive 0.962 0.869 – 1.06 0.454 421 4026 all phecode
558 Noninfectious gastroenteritis Digestive 1.08 1.04 – 1.12 1.36e-05 3458 26408 all phecode
559 Ileostomy status Digestive 1.06 0.987 – 1.13 0.115 957 9565 all phecode
560 Intestinal obstruction without mention of hernia Digestive 1.03 0.993 – 1.07 0.104 3004 24851 all phecode
560.1 Paralytic ileus Digestive 1.01 0.959 – 1.06 0.718 1627 15714 all phecode
560.2 Impaction of intestine Digestive 1.11 0.994 – 1.23 0.0654 387 3779 all phecode
560.3 Peritoneal or intestinal adhesions Digestive 0.937 0.825 – 1.06 0.31 266 2647 all phecode
560.4 Other intestinal obstruction Digestive 0.997 0.947 – 1.05 0.911 1651 16170 all phecode
561 Symptoms involving digestive system Digestive 1.08 1.03 – 1.12 0.000456 2608 21766 all phecode
562 Diverticulosis and diverticulitis Digestive 1 0.974 – 1.03 0.876 6295 23431 all phecode
562.1 Diverticulosis Digestive 1 0.973 – 1.03 0.933 6246 23383 all phecode
562.2 Diverticulitis Digestive 1.05 0.994 – 1.1 0.0854 1611 15162 all phecode
564 Functional digestive disorders Digestive 1.05 1.02 – 1.07 8.1e-05 11411 28676 all phecode
564.1 Irritable Bowel Syndrome Digestive 1.08 1.04 – 1.12 4.06e-05 3457 22266 all phecode
564.9 Personal history of diseases of digestive system Digestive 1.03 0.996 – 1.07 0.076 3074 25861 all phecode
565 Anal and rectal conditions Digestive 1.01 0.973 – 1.05 0.629 3355 30757 all phecode
565.1 Anal and rectal polyp Digestive 1.04 0.978 – 1.1 0.233 1305 12649 all phecode
567 Peritonitis and retroperitoneal infections Digestive 0.997 0.942 – 1.05 0.915 1364 13616 all phecode
568 Other disorders of peritoneum Digestive 1.03 0.981 – 1.08 0.225 1705 17038 all phecode
568.1
Peritoneal adhesions (postoperative)
Peritoneal adhesions (postoperative) (postinfection)
 Digestive 1.03 0.969 – 1.09 0.367 1247 12468 all phecode
569 Other disorders of intestine Digestive 1.03 1 – 1.05 0.0428 8079 35231 all phecode
569.1 Toxic gastroenteritis and colitis Digestive 0.997 0.888 – 1.12 0.955 326 3260 all phecode
569.2 Gastrointestinal complications Digestive 1.02 0.965 – 1.08 0.471 1395 13933 all phecode
571 Chronic liver disease and cirrhosis Digestive 1.04 1.01 – 1.07 0.0185 4610 32562 all phecode
571.5 Other chronic nonalcoholic liver disease Digestive 1.04 1.01 – 1.08 0.00966 4342 32234 all phecode
571.51 Cirrhosis of liver without mention of alcohol Digestive 1.06 0.993 – 1.13 0.0824 1018 10095 all phecode
571.6 Primary biliary cirrhosis Digestive 0.915 0.783 – 1.07 0.259 179 1790 all phecode
571.8
Liver abscess and sequelae of chronic liver
Liver abscess and sequelae of chronic liver disease
 Digestive 0.993 0.928 – 1.06 0.843 950 9498 all phecode
571.81 Portal hypertension Digestive 1.01 0.923 – 1.1 0.871 573 5730 all phecode
572 Ascites (non malignant) Digestive 1.02 0.979 – 1.07 0.319 2278 22675 all phecode
573 Other disorders of liver Digestive 1.01 0.983 – 1.04 0.409 5599 33620 all phecode
573.1 Chronic passive congestion of liver Digestive 1.02 0.854 – 1.21 0.86 136 1359 all phecode
573.2 Liver replaced by transplant Digestive 1.05 0.927 – 1.19 0.452 292 2920 all phecode
573.3 Hepatomegaly Digestive 1.07 0.968 – 1.17 0.196 470 4700 all phecode
573.4 Acute and subacute necrosis of liver Digestive 0.935 0.831 – 1.05 0.268 316 3149 all phecode
573.5 Jaundice (not of newborn) Digestive 1.03 0.966 – 1.11 0.335 958 9496 all phecode
573.6
Nonspecific elevation of levels of transaminase
Nonspecific elevation of levels of transaminase or lactic acid dehydrogenase [LDH]
 Digestive 0.993 0.955 – 1.03 0.737 2756 26470 all phecode
573.7 Abnormal results of function study of liver Digestive 1.01 0.969 – 1.05 0.739 3018 27774 all phecode
573.9 Abnormal serum enzyme levels Digestive 1.01 0.975 – 1.04 0.73 4679 33866 all phecode
574 Cholelithiasis and cholecystitis Digestive 0.987 0.951 – 1.02 0.491 3177 30809 all phecode
574.1 Cholelithiasis Digestive 0.976 0.939 – 1.01 0.212 2924 28874 all phecode
574.11 Cholelithiasis with acute cholecystitis Digestive 0.919 0.82 – 1.03 0.15 342 3412 all phecode
574.12 Cholelithiasis with other cholecystitis Digestive 0.934 0.855 – 1.02 0.133 553 5501 all phecode
574.2 Calculus of bile duct Digestive 1 0.931 – 1.07 0.994 852 8503 all phecode
574.3 Cholecystitis without cholelithiasis Digestive 0.973 0.905 – 1.05 0.451 822 8181 all phecode
575 Other biliary tract disease Digestive 1.01 0.968 – 1.06 0.625 2266 22555 all phecode
575.1 Cholangitis Digestive 1.05 0.939 – 1.17 0.394 354 3530 all phecode
575.2 Obstruction of bile duct Digestive 1.05 0.966 – 1.14 0.255 621 6201 all phecode
575.6 Cholesterolosis of gallbladder Digestive 0.94 0.815 – 1.08 0.391 207 2063 all phecode
575.7 Other disorders of gallbladder Digestive 0.979 0.915 – 1.05 0.545 939 9382 all phecode
575.8 Other disorders of biliary tract Digestive 1.05 0.984 – 1.11 0.146 1154 11523 all phecode
575.9
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of biliary tract
 Digestive 1 0.883 – 1.14 0.969 260 2600 all phecode
577 Diseases of pancreas Digestive 1.01 0.966 – 1.05 0.686 2225 22106 all phecode
577.1 Acute pancreatitis Digestive 1.05 0.991 – 1.12 0.0944 1212 12110 all phecode
577.2 Chronic pancreatitis Digestive 1.1 1 – 1.21 0.0489 495 4950 all phecode
577.3 Cyst and pseudocyst of pancreas Digestive 0.978 0.895 – 1.07 0.623 570 5601 all phecode
578 Gastrointestinal hemorrhage Digestive 1.04 1.01 – 1.07 0.0139 4554 37045 all phecode
578.1 Hematemesis Digestive 1.11 1.01 – 1.22 0.0299 485 4842 all phecode
578.2 Blood in stool Digestive 1.03 0.988 – 1.07 0.17 2743 26554 all phecode
578.8 Hemorrhage of rectum and anus Digestive 1.03 0.982 – 1.07 0.247 2210 21750 all phecode
578.9 Hemorrhage of gastrointestinal tract Digestive 1.06 1 – 1.12 0.0345 1562 15345 all phecode
579 Other symptoms involving abdomen and pelvis Digestive 1.02 0.992 – 1.06 0.137 4431 34209 all phecode
579.2 Splenomegaly Digestive 1.03 0.957 – 1.12 0.405 730 7262 all phecode
579.8 Nonspecific abnormal findings in stool contents Digestive 0.997 0.944 – 1.05 0.922 1410 13877 all phecode
580 Nephritis; nephrosis; renal sclerosis Genitourinary 1.05 0.998 – 1.1 0.0591 1881 15516 all phecode
580.1 Glomerulonephritis Genitourinary 1.02 0.921 – 1.13 0.69 401 3992 all phecode
580.11 Proliferative glomerulonephritis Genitourinary 0.991 0.839 – 1.17 0.918 146 1440 all phecode
580.12 Non-proliferative glomerulonephritis Genitourinary 0.937 0.773 – 1.13 0.503 114 1128 all phecode
580.13 Acute glomerulonephritis, NOS Genitourinary 1.09 0.837 – 1.42 0.52 61 600 all phecode
580.14 Chronic glomerulonephritis, NOS Genitourinary 1.06 0.932 – 1.2 0.389 277 2760 all phecode
580.2
Nephrotic syndrome without mention of
Nephrotic syndrome without mention of glomerulonephritis
 Genitourinary 1.05 0.914 – 1.21 0.491 221 2193 all phecode
580.3
Nephritis and nephropathy without mention of
Nephritis and nephropathy without mention of glomerulonephritis
 Genitourinary 1.05 0.989 – 1.1 0.119 1502 11930 all phecode
580.31
Nephritis and nephropathy in diseases
Nephritis and nephropathy in diseases classified elsewhere
 Genitourinary 1.05 0.979 – 1.12 0.175 992 7228 all phecode
580.32
Nephritis and nephropathy with pathological
Nephritis and nephropathy with pathological lesion
 Genitourinary 1.01 0.931 – 1.09 0.847 683 6612 all phecode
580.4 Renal sclerosis, NOS Genitourinary 1.09 0.974 – 1.22 0.133 340 3400 all phecode
585 Renal failure Genitourinary 1.07 1.04 – 1.09 2.21e-06 7470 32340 all phecode
585.1 Acute renal failure Genitourinary 1.07 1.04 – 1.11 3.22e-05 4265 27230 all phecode
585.2 Renal failure NOS Genitourinary 1.04 0.97 – 1.12 0.259 832 8162 all phecode
585.3 Chronic renal failure [CKD] Genitourinary 1.07 1.04 – 1.1 6.65e-06 5580 29470 all phecode
585.31 Renal dialysis Genitourinary 1.05 0.972 – 1.13 0.22 747 7423 all phecode
585.32 End stage renal disease Genitourinary 1.05 0.98 – 1.12 0.173 1007 9783 all phecode
585.33 Chronic Kidney Disease, Stage III Genitourinary 1.06 1.02 – 1.1 0.00542 3209 21312 all phecode
585.34 Chronic Kidney Disease, Stage IV Genitourinary 1.06 0.987 – 1.13 0.113 977 9190 all phecode
585.4 Chronic kidney disease, Stage I or II Genitourinary 1.06 0.995 – 1.12 0.0737 1227 11191 all phecode
586 Other disorders of the kidney and ureters Genitourinary 1.03 1.01 – 1.06 0.0092 7628 34189 all phecode
586.1 Anatomical abnormatilies of kidney and ureters Genitourinary 1.1 0.988 – 1.23 0.0792 349 3480 all phecode
586.11 Small kidney Genitourinary 1.12 0.969 – 1.3 0.123 210 2093 all phecode
586.12 Vesicoureteral reflux Genitourinary 1.13 0.949 – 1.35 0.169 136 1360 all phecode
586.2 Cyst of kidney, acquired Genitourinary 0.981 0.928 – 1.04 0.503 1381 12912 all phecode
586.3 Vascular disorders of kidney/hypertrophy Genitourinary 0.986 0.847 – 1.15 0.851 187 1862 all phecode
586.4 Stricture/obstruction of ureter Genitourinary 1.01 0.962 – 1.06 0.7 1821 17115 all phecode
587 Kidney replaced by transpant Genitourinary 1.04 0.969 – 1.12 0.262 819 8134 all phecode
588 Disorders resulting from impaired renal function Genitourinary 1.06 0.989 – 1.13 0.105 976 9389 all phecode
588.1 Renal osteodystrophy Genitourinary 0.996 0.881 – 1.13 0.953 290 2900 all phecode
588.2 Secondary hyperparathyroidism (of renal origin) Genitourinary 1.07 0.997 – 1.16 0.0616 755 7275 all phecode
589 Abnormal results of function study of kidney Genitourinary 1.04 0.974 – 1.11 0.243 1007 9834 all phecode
590 Pyelonephritis Genitourinary 1.04 0.982 – 1.1 0.187 1461 14350 all phecode
591 Urinary tract infection Genitourinary 1.02 0.997 – 1.04 0.0832 9873 32513 all phecode
592 Cystitis and urethritis Genitourinary 1.02 0.979 – 1.06 0.397 3038 24207 all phecode
592.1 Cystitis Genitourinary 1.01 0.969 – 1.05 0.695 2880 23279 all phecode
592.11 Acute cystitis Genitourinary 0.983 0.935 – 1.03 0.488 1783 16452 all phecode
592.12 Chronic cystitis Genitourinary 0.993 0.865 – 1.14 0.915 239 2343 all phecode
592.13 Chronic interstitial cystitis Genitourinary 1.06 0.962 – 1.17 0.236 431 4310 all phecode
592.2 Urethritis and urethral syndrome Genitourinary 1.08 0.939 – 1.25 0.271 210 2093 all phecode
593 Hematuria Genitourinary 1.03 0.997 – 1.06 0.0763 4859 32063 all phecode
593.1 Gross hematuria Genitourinary 0.986 0.935 – 1.04 0.59 1585 14824 all phecode
593.2 Microscopic hematuria Genitourinary 1.03 0.966 – 1.1 0.359 1049 10301 all phecode
594 Urinary calculus Genitourinary 1.05 1.02 – 1.08 0.000522 6707 38209 all phecode
594.1 Calculus of kidney Genitourinary 1.05 1.02 – 1.08 0.000616 6273 38051 all phecode
594.2 Calculus of lower urinary tract Genitourinary 1.07 0.959 – 1.19 0.229 366 3638 all phecode
594.3 Calculus of ureter Genitourinary 1.04 0.987 – 1.1 0.129 1361 13561 all phecode
594.8 Renal colic Genitourinary 1.12 1 – 1.25 0.0505 356 3560 all phecode
595 Hydronephrosis Genitourinary 1.05 0.997 – 1.1 0.0653 1670 16658 all phecode
596 Other disorders of bladder Genitourinary 1.03 0.996 – 1.07 0.0816 3074 28020 all phecode
596.1 Bladder neck obstruction Genitourinary 1.06 0.959 – 1.18 0.25 400 3942 all phecode
596.5 Functional disorders of bladder Genitourinary 1.02 0.97 – 1.07 0.441 1719 17049 all phecode
597 Other disorders of urethra and urinary tract Genitourinary 1.06 0.996 – 1.12 0.0655 1211 11998 all phecode
597.1 Urethral stricture (not specified as infectious) Genitourinary 1.09 1.01 – 1.18 0.0365 661 6537 all phecode
597.2 Urinary complications NEC Genitourinary 0.995 0.933 – 1.06 0.874 1049 10479 all phecode
597.8 Urethral hypermobility/ISD Genitourinary 1.1 0.948 – 1.28 0.208 189 1873 all phecode
598 Abnormal findings on examination of urine Genitourinary 1.02 0.854 – 1.21 0.864 138 1356 all phecode
598.4 Other cells and casts in urine Genitourinary 0.949 0.788 – 1.14 0.583 122 1192 all phecode
599 Other symptoms/disorders or the urinary system Genitourinary 1.02 1 – 1.04 0.0366 14168 30681 all phecode
599.1 Urinary obstruction Genitourinary 0.983 0.91 – 1.06 0.654 728 6861 all phecode
599.2 Retention of urine Genitourinary 1.02 0.985 – 1.05 0.319 5034 28305 all phecode
599.3 Dysuria Genitourinary 1.01 0.982 – 1.05 0.386 4397 27849 all phecode
599.4 Urinary incontinence Genitourinary 1.04 1.01 – 1.07 0.0107 5599 26960 all phecode
599.5 Frequency of urination and polyuria Genitourinary 1.03 1 – 1.06 0.0446 5498 28723 all phecode
599.6 Oliguria and anuria Genitourinary 1.06 0.975 – 1.16 0.166 599 5902 all phecode
599.7 Urethral discharge Genitourinary 0.908 0.755 – 1.09 0.306 118 1175 all phecode
599.8 Other symptoms involving urinary system Genitourinary 1.03 0.996 – 1.06 0.0896 5446 27963 all phecode
599.9 Other abnormality of urination Genitourinary 1.04 0.997 – 1.08 0.0742 3041 24877 all phecode
600 Hyperplasia of prostate Genitourinary 1 0.962 – 1.04 0.986 4063 11364 all phecode
601 Inflammatory diseases of prostate Genitourinary 0.974 0.913 – 1.04 0.43 1044 9665 all phecode
601.1 Prostatitis Genitourinary 0.988 0.897 – 1.09 0.797 477 4596 all phecode
601.11 Acute prostatitis Genitourinary 0.878 0.732 – 1.05 0.16 124 1200 all phecode
601.12 Chronic prostatitis Genitourinary 1.13 0.912 – 1.4 0.261 95 943 all phecode
601.3 Orchitis and epididymitis Genitourinary 1.02 0.918 – 1.13 0.722 389 3822 all phecode
601.4 Balanoposthitis Genitourinary 0.99 0.823 – 1.19 0.918 127 1224 all phecode
601.8
Other inflammatory disorders of male genital
Other inflammatory disorders of male genital organs
 Genitourinary 0.926 0.783 – 1.09 0.365 161 1591 all phecode
602 Other disorders of prostate Genitourinary 0.956 0.857 – 1.07 0.417 361 3399 all phecode
602.3 Dysplasia of prostate Genitourinary 1.03 0.823 – 1.3 0.778 77 730 all phecode
603 Other disorders of testis Genitourinary 0.952 0.86 – 1.05 0.337 440 4354 all phecode
603.1 Hydrocele Genitourinary 1.01 0.891 – 1.14 0.887 293 2882 all phecode
603.2 Spermatocele Genitourinary 0.885 0.748 – 1.05 0.154 156 1539 all phecode
604 Disorders of penis Genitourinary 1.02 0.939 – 1.1 0.684 685 6748 all phecode
604.1 Redundant prepuce and phimosis/BXO Genitourinary 1.05 0.889 – 1.24 0.559 155 1540 all phecode
604.3 Peyronie's disease Genitourinary 0.96 0.833 – 1.11 0.568 215 2132 all phecode
605 Erectile dysfunction [ED] Genitourinary 0.983 0.946 – 1.02 0.367 3776 12700 all phecode
608 Other disorders of male genital organs Genitourinary 1.01 0.958 – 1.06 0.741 1645 13758 all phecode
609 Male infertility and abnormal spermatozoa Genitourinary 0.942 0.851 – 1.04 0.242 424 4196 all phecode
609.1 Infertility, male Genitourinary 0.949 0.842 – 1.07 0.389 302 2992 all phecode
609.11 Azoospermia and oligospermia Genitourinary 0.932 0.752 – 1.15 0.52 95 950 all phecode
609.2 Abnormal spermatozoa Genitourinary 0.931 0.79 – 1.1 0.395 154 1519 all phecode
610 Benign mammary dysplasias Genitourinary 0.98 0.945 – 1.02 0.274 3683 16548 all phecode
610.1 Cystic mastopathy Genitourinary 0.998 0.947 – 1.05 0.931 1633 14191 all phecode
610.2 Fibroadenosis of breast Genitourinary 1.06 0.8 – 1.42 0.668 60 600 all phecode
610.4 Benign neoplasm of breast Genitourinary 0.966 0.928 – 1.01 0.1 2837 16430 all phecode
610.8 Other specified benign mammary dysplasias Genitourinary 0.99 0.933 – 1.05 0.731 1269 12191 all phecode
611 Abnormal findings on mammogram or breast exam Genitourinary 0.965 0.937 – 0.995 0.0209 6067 18690 all phecode
611.1 Abnormal mammogram Genitourinary 0.955 0.924 – 0.986 0.00532 4980 16120 all phecode
611.11 Mammographic microcalcification Genitourinary 0.906 0.851 – 0.964 0.00188 1122 10394 all phecode
611.3 Lump or mass in breast Genitourinary 0.975 0.94 – 1.01 0.174 3549 18572 all phecode
612
Breast conditions, congenital or relating to
Breast conditions, congenital or relating to hormones
 Genitourinary 0.979 0.918 – 1.04 0.52 1051 10425 all phecode
612.1 Galactorrhea Genitourinary 1.19 0.999 – 1.42 0.0513 139 1390 all phecode
612.2 Hypertrophy of breast (Gynecomastia) Genitourinary 0.969 0.9 – 1.04 0.405 800 7962 all phecode
612.3 Congenital anomalies of breast Genitourinary 0.819 0.655 – 1.02 0.0803 83 810 all phecode
613 Other nonmalignant breast conditions Genitourinary 0.992 0.958 – 1.03 0.634 3897 22072 all phecode
613.1 Inflammatory disease of breast Genitourinary 0.931 0.856 – 1.01 0.094 593 5874 all phecode
613.5 Mastodynia Genitourinary 1.01 0.964 – 1.07 0.578 1675 16203 all phecode
613.7 Other signs and symptoms in breast Genitourinary 1.02 0.948 – 1.09 0.635 883 8754 all phecode
613.8 Other specified disorders of breast Genitourinary 0.981 0.916 – 1.05 0.574 932 9248 all phecode
613.9 Breast disorder NOS Genitourinary 0.983 0.931 – 1.04 0.544 1465 14174 all phecode
614 Inflammatory diseases of female pelvic organs Genitourinary 1.02 0.985 – 1.06 0.254 3715 19647 all phecode
614.1
Pelvic peritoneal adhesions, female
Pelvic peritoneal adhesions, female (postoperative) (postinfection)
 Genitourinary 0.998 0.892 – 1.12 0.975 337 3370 all phecode
614.3 Pelvic inflammatory disease (PID) Genitourinary 1.03 0.933 – 1.13 0.595 478 4773 all phecode
614.31 Acute inflammatory pelvic disease Genitourinary 1.04 0.839 – 1.28 0.742 94 933 all phecode
614.32 Chronic inflammatory pelvic disease Genitourinary 0.982 0.843 – 1.14 0.813 186 1842 all phecode
614.33 Pelvic inflammatory disease, NOS Genitourinary 1.03 0.898 – 1.17 0.695 246 2460 all phecode
614.4 Inflammatory diseases of uterus, except cervix Genitourinary 1.05 0.893 – 1.23 0.569 165 1639 all phecode
614.5
Inflammatory disease of cervix, vagina, and
Inflammatory disease of cervix, vagina, and vulva
 Genitourinary 1.02 0.978 – 1.05 0.428 3180 19539 all phecode
614.51 Cervicitis and endocervicitis Genitourinary 0.986 0.868 – 1.12 0.821 264 2640 all phecode
614.52 Vaginitis and vulvovaginitis Genitourinary 1.03 0.986 – 1.07 0.205 2732 18924 all phecode
614.53 Cyst or abscess of Bartholin's gland Genitourinary 1.1 0.923 – 1.32 0.284 132 1311 all phecode
614.54 Abscess or ulceration of vulva Genitourinary 0.995 0.868 – 1.14 0.944 225 2244 all phecode
615 Endometriosis Genitourinary 1.06 1.01 – 1.12 0.0207 1585 14666 all phecode
618 Genital prolapse Genitourinary 1.01 0.967 – 1.06 0.592 2079 17915 all phecode
618.1 Prolapse of vaginal walls Genitourinary 1.01 0.951 – 1.06 0.852 1408 13456 all phecode
618.2 Uterine/Uterovaginal prolapse Genitourinary 0.958 0.876 – 1.05 0.341 542 5390 all phecode
618.5 Prolapse of vaginal vault after hysterectomy Genitourinary 1.1 0.978 – 1.23 0.112 317 3162 all phecode
618.6 Vaginal enterocele, congenital or acquired Genitourinary 1.18 1.07 – 1.3 0.00102 441 4394 all phecode
619 Noninflammatory female genital disorders Genitourinary 0.979 0.95 – 1.01 0.17 5728 18687 all phecode
619.1
Noninflammatory disorders of ovary, fallopian
Noninflammatory disorders of ovary, fallopian tube, and broad ligament
 Genitourinary 0.971 0.915 – 1.03 0.328 1233 12082 all phecode
619.2 Disorders of uterus, NEC Genitourinary 1.07 0.982 – 1.16 0.126 591 5897 all phecode
619.3 Noninflammatory disorders of cervix Genitourinary 0.986 0.897 – 1.08 0.771 483 4823 all phecode
619.4 Noninflammatory disorders of vagina Genitourinary 0.97 0.93 – 1.01 0.165 2525 18404 all phecode
619.5 Noninflammatory disorders of vulva and perineum Genitourinary 0.987 0.929 – 1.05 0.669 1189 11717 all phecode
620 Dysplasia of female genital organs Genitourinary 0.998 0.9 – 1.11 0.972 395 3950 all phecode
620.1 Dysplasia of cervix Genitourinary 0.9 0.773 – 1.05 0.175 178 1780 all phecode
621 Endometrial hyperplasia Genitourinary 0.972 0.881 – 1.07 0.572 437 4370 all phecode
622 Polyp of female genital organs Genitourinary 0.959 0.908 – 1.01 0.128 1449 14264 all phecode
622.1 Polyp of corpus uteri Genitourinary 0.977 0.918 – 1.04 0.451 1132 11189 all phecode
622.2 Mucous polyp of cervix Genitourinary 0.891 0.808 – 0.983 0.0211 445 4444 all phecode
623 Hypertrophy of female genital organs Genitourinary 0.983 0.914 – 1.06 0.636 824 8165 all phecode
624 Symptoms involving female genital tract Genitourinary 0.983 0.929 – 1.04 0.564 1348 12518 all phecode
624.1 Dystrophy of female genital tract Genitourinary 1.02 0.881 – 1.17 0.835 216 2155 all phecode
624.2 Atrophy of female genital tract Genitourinary 1.03 0.788 – 1.33 0.851 64 615 all phecode
624.9 stress incontinence, female Genitourinary 1.03 0.98 – 1.08 0.251 1935 15408 all phecode
625
Pain and other symptoms associated with female
Pain and other symptoms associated with female genital organs
 Genitourinary 0.993 0.963 – 1.02 0.644 5653 17303 all phecode
625.1 Dyspareunia Genitourinary 1.03 0.971 – 1.09 0.329 1267 12474 all phecode
626
Disorders of menstruation and other abnormal
Disorders of menstruation and other abnormal bleeding from female genital tract
 Genitourinary 0.956 0.927 – 0.986 0.00429 5940 15585 all phecode
626.1 Irregular menstrual cycle/bleeding Genitourinary 0.949 0.917 – 0.983 0.00366 4315 14604 all phecode
626.11 Absent or infrequent menstruation Genitourinary 0.928 0.87 – 0.99 0.024 1062 8531 all phecode
626.12 Excessive or frequent menstruation Genitourinary 0.961 0.917 – 1.01 0.0982 2097 11991 all phecode
626.13 Irregular menstrual cycle Genitourinary 0.967 0.921 – 1.01 0.169 1957 12265 all phecode
626.14 Irregular menstrual bleeding Genitourinary 0.967 0.904 – 1.03 0.32 970 8996 all phecode
626.15 Infertility, female, associated with anovulation Genitourinary 0.942 0.848 – 1.05 0.267 394 3789 all phecode
626.2 Dysmenorrhea Genitourinary 1 0.946 – 1.06 0.967 1373 9857 all phecode
626.4 Premenstrual tension syndromes Genitourinary 0.978 0.874 – 1.09 0.691 336 3308 all phecode
626.8 Infertility, female Genitourinary 0.912 0.847 – 0.981 0.0138 817 6741 all phecode
627 Menopausal and postmenopausal disorders Genitourinary 0.967 0.934 – 1 0.0495 4560 14557 all phecode
627.1 Postmenopausal bleeding Genitourinary 0.973 0.914 – 1.04 0.382 1146 10338 all phecode
627.2 Symptomatic menopause Genitourinary 0.964 0.926 – 1 0.0752 3017 13763 all phecode
627.21 Symptomatic artificial menopause Genitourinary 0.815 0.688 – 0.966 0.0181 152 1514 all phecode
627.22
Need for Hormone replacement therapy
Need for Hormone replacement therapy (postmenopausal)
 Genitourinary 0.962 0.86 – 1.08 0.501 356 3513 all phecode
627.3 Postmenopausal atrophic vaginitis Genitourinary 0.987 0.924 – 1.05 0.707 997 9484 all phecode
627.4 Premenopausal menorrhagia Genitourinary 1 0.898 – 1.12 0.987 361 3580 all phecode
627.5 Premature menopause and other ovarian failure Genitourinary 0.859 0.764 – 0.966 0.0109 309 3082 all phecode
628 Ovarian cyst Genitourinary 0.996 0.949 – 1.04 0.854 1945 13838 all phecode
634 Miscarriage; stillbirth Pregnancy Complications 0.959 0.893 – 1.03 0.253 826 8047 all phecode
634.1 Missed abortion/Hydatidiform mole Pregnancy Complications 0.959 0.845 – 1.09 0.516 273 2715 all phecode
634.3 Ectopic pregnancy Pregnancy Complications 0.957 0.79 – 1.16 0.65 117 1170 all phecode
635
Hemorrhage during pregnancy; childbirth and
Hemorrhage during pregnancy; childbirth and postpartum
 Pregnancy Complications 0.935 0.857 – 1.02 0.129 563 5309 all phecode
635.2
Antepartum hemorrhage, abruptio placentae, and
Antepartum hemorrhage, abruptio placentae, and placenta previa
 Pregnancy Complications 0.918 0.825 – 1.02 0.118 370 3629 all phecode
635.3 Placenta previa and abruptio placenta Pregnancy Complications 0.919 0.814 – 1.04 0.176 288 2850 all phecode
636
Early or threatened labor; hemorrhage in early
Early or threatened labor; hemorrhage in early pregnancy
 Pregnancy Complications 0.986 0.925 – 1.05 0.667 1080 7870 all phecode
636.1 Threatened premature labor Pregnancy Complications 1.03 0.923 – 1.14 0.64 380 3799 all phecode
636.2 Early onset of delivery Pregnancy Complications 0.97 0.861 – 1.09 0.619 288 2868 all phecode
636.3 Hemorrhage in early pregnancy Pregnancy Complications 0.998 0.905 – 1.1 0.966 441 4365 all phecode
636.8 Cervical incompetence Pregnancy Complications 1.17 0.922 – 1.49 0.195 77 770 all phecode
637
Short gestation; low birth weight; and fetal
Short gestation; low birth weight; and fetal growth retardation
 Pregnancy Complications 1.13 0.906 – 1.41 0.278 85 850 all phecode
642
Hypertension complicating pregnancy
Hypertension complicating pregnancy, childbirth, and the puerperium
 Pregnancy Complications 1.02 0.941 – 1.11 0.581 585 5725 all phecode
642.1 Preeclampsia and eclampsia Pregnancy Complications 1.02 0.903 – 1.14 0.784 302 3013 all phecode
643 Excessive vomiting in pregnancy Pregnancy Complications 1.16 1.02 – 1.32 0.028 252 2506 all phecode
643.1 Hyperemesis gravidarum Pregnancy Complications 1.17 0.964 – 1.41 0.113 119 1190 all phecode
644 Anemia during pregnancy Pregnancy Complications 1.04 0.905 – 1.2 0.581 224 2224 all phecode
646 Other complications of pregnancy NEC Pregnancy Complications 1.03 0.957 – 1.11 0.445 855 6531 all phecode
647
Infectious and parasitic complications
Infectious and parasitic complications affecting pregnancy
 Pregnancy Complications 1 0.868 – 1.16 0.986 211 2093 all phecode
647.1
Infections of genitourinary tract during
Infections of genitourinary tract during pregnancy
 Pregnancy Complications 1.2 1.04 – 1.38 0.0107 222 2213 all phecode
647.3 Major puerperal infection Pregnancy Complications 0.866 0.667 – 1.12 0.281 65 650 all phecode
649
Other conditions or status of the mother
Other conditions or status of the mother complicating pregnancy, childbirth, or the puerperium
 Pregnancy Complications 1 0.946 – 1.07 0.877 1275 8010 all phecode
649.1
Diabetes or abnormal glucose tolerance
Diabetes or abnormal glucose tolerance complicating pregnancy
 Pregnancy Complications 1.05 0.966 – 1.14 0.261 649 5687 all phecode
653
Problems associated with amniotic cavity and
Problems associated with amniotic cavity and membranes
 Pregnancy Complications 1.05 0.963 – 1.14 0.276 587 5463 all phecode
654.1
Abnormality of organs and soft tissues of
Abnormality of organs and soft tissues of pelvis complicating pregnancy, childbirth, or the puerperium
 Pregnancy Complications 1.06 0.916 – 1.22 0.453 207 2055 all phecode
654.2 Rhesus isoimmunization in pregnancy Pregnancy Complications 1.02 0.888 – 1.18 0.737 204 2040 all phecode
655
Known or suspected fetal abnormality affecting
Known or suspected fetal abnormality affecting management of mother
 Pregnancy Complications 0.975 0.925 – 1.03 0.349 1624 10064 all phecode
655.1 Abnormality in fetal heart rate or rhythm Pregnancy Complications 0.961 0.884 – 1.04 0.349 616 5533 all phecode
656 Other perinatal conditions of fetus or newborn Pregnancy Complications 1.03 0.957 – 1.1 0.47 898 7014 all phecode
656.2 Respiratory conditions of fetus and newborn Pregnancy Complications 1.09 0.854 – 1.39 0.485 66 660 all phecode
669 Complications of labor and delivery NEC Pregnancy Complications 1 0.932 – 1.07 0.997 887 6802 all phecode
671
Venous/cerebrovascular complications embolism
Venous/cerebrovascular complications embolism in pregnancy and the puerperium
 Pregnancy Complications 0.919 0.803 – 1.05 0.224 236 2351 all phecode
674 Other complications of the puerperium NEC Pregnancy Complications 1.08 0.915 – 1.27 0.37 158 1580 all phecode
676
Other disorders of the breast associated with
Other disorders of the breast associated with childbirth and disorders of lactation
 Pregnancy Complications 0.892 0.767 – 1.04 0.14 184 1814 all phecode
681 Superficial cellulitis and abscess Dermatologic 1.01 0.98 – 1.03 0.635 6500 38394 all phecode
681.1 Cellulitis and abscess of fingers/toes Dermatologic 0.979 0.923 – 1.04 0.49 1256 11462 all phecode
681.2 Cellulitis and abscess of face/neck Dermatologic 0.993 0.93 – 1.06 0.827 1007 9981 all phecode
681.3 Cellulitis and abscess of arm/hand Dermatologic 0.987 0.943 – 1.03 0.564 2123 19952 all phecode
681.5 Cellulitis and abscess of leg, except foot Dermatologic 0.981 0.938 – 1.02 0.383 2252 20944 all phecode
681.6 Cellulitis and abscess of foot, toe Dermatologic 1.01 0.958 – 1.06 0.793 1820 16893 all phecode
681.7 Cellulitis and abscess of trunk Dermatologic 1.07 1.02 – 1.13 0.0118 1572 15588 all phecode
686
Other local infections of skin and subcutaneous
Other local infections of skin and subcutaneous tissue
 Dermatologic 1.04 0.993 – 1.08 0.0977 2257 21750 all phecode
686.1 Carbuncle and furuncle Dermatologic 0.971 0.889 – 1.06 0.504 558 5504 all phecode
686.2 Impetigo Dermatologic 1.07 0.966 – 1.18 0.199 414 4117 all phecode
686.3 Pilonidal cyst Dermatologic 0.969 0.824 – 1.14 0.701 160 1594 all phecode
686.4 Pyogenic granuloma Dermatologic 1.11 0.94 – 1.32 0.214 158 1570 all phecode
686.5 Pyoderma Dermatologic 1.21 0.924 – 1.59 0.166 63 630 all phecode
687 Symptoms affecting skin Dermatologic 0.994 0.945 – 1.05 0.807 1690 16343 all phecode
687.1 Rash and other nonspecific skin eruption Dermatologic 0.975 0.95 – 1 0.0604 7007 34623 all phecode
687.3 Changes in skin texture Dermatologic 0.993 0.899 – 1.1 0.886 415 4121 all phecode
687.4 Disturbance of skin sensation Dermatologic 1.03 0.999 – 1.05 0.0596 6375 34216 all phecode
689 Disorder of skin and subcutaneous tissue NOS Dermatologic 0.963 0.941 – 0.986 0.00168 9311 37335 all phecode
690 Erythematosquamous dermatosis Dermatologic 0.957 0.929 – 0.986 0.00432 5184 31581 all phecode
690.1 Seborrheic dermatitis Dermatologic 0.957 0.928 – 0.986 0.00409 5174 31553 all phecode
691 Congenital anomalies of skin Dermatologic 0.959 0.878 – 1.05 0.355 541 5337 all phecode
691.3 Congenital pigmentary anomalies of skin Dermatologic 0.821 0.632 – 1.07 0.138 62 613 all phecode
694 Dyschromia and Vitiligo Dermatologic 0.952 0.907 – 1 0.0492 1861 17936 all phecode
694.1 Vitiligo Dermatologic 0.998 0.835 – 1.19 0.978 137 1347 all phecode
694.2 Other dyschromia Dermatologic 0.947 0.899 – 0.997 0.0377 1674 16183 all phecode
694.3 Vascular disorders of skin Dermatologic 1.23 0.978 – 1.55 0.0769 82 819 all phecode
695 Erythematous conditions Dermatologic 0.997 0.965 – 1.03 0.877 4120 30247 all phecode
695.1 Toxic erythema Dermatologic 1.16 0.905 – 1.48 0.242 70 688 all phecode
695.2 Bullous dermatoses Dermatologic 1.03 0.827 – 1.29 0.78 85 805 all phecode
695.3 Rosacea Dermatologic 0.966 0.92 – 1.01 0.166 1816 17663 all phecode
695.4 Lupus (localized and systemic) Dermatologic 1.05 0.971 – 1.14 0.217 672 6686 all phecode
695.41 Cutaneous lupus erythematosus Dermatologic 1.02 0.896 – 1.16 0.75 247 2437 all phecode
695.42 Systemic lupus erythematosus Dermatologic 1.07 0.985 – 1.16 0.11 637 6337 all phecode
695.7 Prurigo and Lichen Dermatologic 1.02 0.934 – 1.11 0.713 605 5986 all phecode
695.8 Other specified erythematous conditions Dermatologic 1.02 0.951 – 1.1 0.545 812 7980 all phecode
695.81 Erythema nodosum Dermatologic 0.83 0.626 – 1.1 0.193 55 550 all phecode
695.9 Unspecified erythematous condition Dermatologic 1.03 0.954 – 1.12 0.429 679 6756 all phecode
696 Psoriasis and related disorders Dermatologic 1.01 0.952 – 1.06 0.806 1401 13832 all phecode
696.3 Pityriasis Dermatologic 1.04 0.826 – 1.31 0.728 92 904 all phecode
696.4 Psoriasis Dermatologic 1.01 0.957 – 1.07 0.649 1311 12976 all phecode
696.41 Psoriasis vulgaris Dermatologic 1.01 0.95 – 1.07 0.788 1200 11867 all phecode
696.42 Psoriatic arthropathy Dermatologic 1.01 0.889 – 1.14 0.893 282 2810 all phecode
697 Sarcoidosis Dermatologic 1.02 0.907 – 1.14 0.76 333 3330 all phecode
698 Pruritus and related conditions Dermatologic 1 0.962 – 1.05 0.831 2254 21889 all phecode
700 Corns and callosities Dermatologic 0.992 0.936 – 1.05 0.781 1373 10894 all phecode
701
Other hypertrophic and atrophic conditions of
Other hypertrophic and atrophic conditions of skin
 Dermatologic 0.982 0.958 – 1.01 0.159 7651 38050 all phecode
701.1 Keratoderma, acquired Dermatologic 0.972 0.891 – 1.06 0.518 567 5524 all phecode
701.2 Scar conditions and fibrosis of skin Dermatologic 0.949 0.907 – 0.992 0.021 2184 21550 all phecode
701.3 Circumscribed scleroderma Dermatologic 0.998 0.915 – 1.09 0.966 571 5660 all phecode
701.4 Keloid scar Dermatologic 0.985 0.904 – 1.07 0.731 578 5716 all phecode
701.5 Abnormal granulation tissue Dermatologic 1 0.904 – 1.11 0.952 400 3982 all phecode
702
Degenerative skin conditions and other
Degenerative skin conditions and other dermatoses
 Dermatologic 0.949 0.924 – 0.976 0.000188 6956 29525 all phecode
702.1 Actinic keratosis Dermatologic 0.957 0.925 – 0.99 0.0107 4171 26529 all phecode
702.2 Seborrheic keratosis Dermatologic 0.944 0.917 – 0.973 0.000145 5480 31552 all phecode
702.4 Degenerative skin disorders Dermatologic 0.902 0.729 – 1.12 0.346 86 832 all phecode
703 Diseases of nail, NOS Dermatologic 1.02 0.97 – 1.08 0.411 1650 14562 all phecode
703.1 Ingrowing nail Dermatologic 1.07 0.997 – 1.15 0.0599 920 8597 all phecode
704 Diseases of hair and hair follicles Dermatologic 0.976 0.94 – 1.01 0.205 3118 29542 all phecode
704.1 Alopecia Dermatologic 1 0.947 – 1.06 0.972 1408 13871 all phecode
704.11 Alopecia Areata Dermatologic 0.893 0.716 – 1.11 0.313 82 811 all phecode
704.12 Telogen effluvium Dermatologic 1.04 0.796 – 1.37 0.757 63 615 all phecode
704.2 Hirsutism Dermatologic 0.965 0.858 – 1.08 0.55 299 2946 all phecode
704.8
Other specified diseases of hair and hair
Other specified diseases of hair and hair follicles
 Dermatologic 0.974 0.927 – 1.02 0.301 1752 17189 all phecode
705 Disorders of sweat glands Dermatologic 0.978 0.9 – 1.06 0.605 603 6012 all phecode
705.1 Dyshidrosis Dermatologic 0.838 0.711 – 0.988 0.0358 154 1540 all phecode
705.3 Hidradenitis Dermatologic 1.08 0.945 – 1.23 0.267 245 2440 all phecode
705.8 Hyperhidrosis Dermatologic 1.05 0.982 – 1.11 0.159 1112 10986 all phecode
706 Diseases of sebaceous glands Dermatologic 0.963 0.937 – 0.99 0.00743 5995 39748 all phecode
706.1 Acne Dermatologic 0.953 0.914 – 0.993 0.0212 2594 22570 all phecode
706.2 Sebaceous cyst Dermatologic 0.96 0.922 – 0.998 0.0405 2814 26819 all phecode
706.3 Seborrhea Dermatologic 0.909 0.705 – 1.17 0.461 59 582 all phecode
706.8 Other specified diseases of sebaceous glands Dermatologic 0.976 0.928 – 1.03 0.361 1684 15289 all phecode
707 Chronic ulcer of skin Dermatologic 1.06 1.02 – 1.1 0.00466 2871 26816 all phecode
707.1 Decubitus ulcer Dermatologic 1 0.933 – 1.08 0.946 825 8119 all phecode
707.2 Chronic ulcer of leg or foot Dermatologic 1.05 0.99 – 1.12 0.101 1108 9992 all phecode
707.3 Chronic ulcer of unspecified site Dermatologic 1.09 1.04 – 1.15 0.000777 1641 16172 all phecode
709 Diffuse diseases of connective tissue Dermatologic 1.06 1.01 – 1.12 0.0283 1477 14427 all phecode
709.2 Sicca syndrome Dermatologic 1.06 0.963 – 1.16 0.249 505 4986 all phecode
709.3 Systemic sclerosis Dermatologic 1.02 0.891 – 1.18 0.741 224 2209 all phecode
709.5 Dermatomyositis Dermatologic 1.06 0.862 – 1.31 0.567 92 892 all phecode
709.6
Other specified diffuse diseases of connective
Other specified diffuse diseases of connective tissue
 Dermatologic 1.27 1.02 – 1.59 0.0308 90 892 all phecode
709.7 Unspecified diffuse connective tissue disease Dermatologic 1.09 1.01 – 1.16 0.0183 917 9089 all phecode
710
Osteomyelitis, periostitis, and other
Osteomyelitis, periostitis, and other infections involving bone
 Musculoskeletal 1.07 1.01 – 1.13 0.0301 1254 12103 all phecode
710.1 Osteomyelitis Musculoskeletal 1.07 1 – 1.13 0.0364 1203 11636 all phecode
710.11 Acute osteomyelitis Musculoskeletal 1.17 1.07 – 1.27 0.000434 590 5708 all phecode
710.12 Chronic osteomyelitis Musculoskeletal 1.1 1 – 1.2 0.0416 531 5163 all phecode
710.19 Unspecified osteomyelitis Musculoskeletal 1.06 0.999 – 1.13 0.0547 1153 11149 all phecode
711 Arthropathy associated with infections Musculoskeletal 1.07 0.963 – 1.19 0.21 410 4099 all phecode
711.1 Pyogenic arthritis Musculoskeletal 1.07 0.947 – 1.21 0.274 290 2900 all phecode
712 Infective connective tissue disorders Musculoskeletal 0.93 0.792 – 1.09 0.376 178 1776 all phecode
713
Arthropathy associated with other disorders
Arthropathy associated with other disorders classified elsewhere
 Musculoskeletal 1.02 0.904 – 1.15 0.757 314 3028 all phecode
713.5
Arthropathy associated with neurological
Arthropathy associated with neurological disorders
 Musculoskeletal 1.02 0.873 – 1.18 0.846 194 1824 all phecode
714
Rheumatoid arthritis and other inflammatory
Rheumatoid arthritis and other inflammatory polyarthropathies
 Musculoskeletal 1.08 1.03 – 1.13 0.000682 2086 18159 all phecode
714.1 Rheumatoid arthritis Musculoskeletal 1.09 1.03 – 1.14 0.00173 1670 15087 all phecode
714.2 Juvenile rheumatoid arthritis Musculoskeletal 0.87 0.693 – 1.09 0.228 77 767 all phecode
715 Other inflammatory spondylopathies Musculoskeletal 1.1 1.03 – 1.16 0.00299 1209 11967 all phecode
715.1 Sacroiliitis NEC Musculoskeletal 1.21 1.07 – 1.38 0.00361 262 2611 all phecode
715.2 Ankylosing spondylitis Musculoskeletal 1.01 0.88 – 1.17 0.857 219 2182 all phecode
716 Other arthropathies Musculoskeletal 1.08 1.05 – 1.1 1.25e-11 13482 31305 all phecode
716.1 Unspecified polyarthropathy or polyarthritis Musculoskeletal 1.15 0.986 – 1.33 0.0759 192 1920 all phecode
716.2 Unspecified monoarthritis Musculoskeletal 0.993 0.829 – 1.19 0.94 131 1293 all phecode
716.9 Arthropathy NOS Musculoskeletal 1.08 1.05 – 1.1 2.49e-11 13410 31294 all phecode
717 Polymyalgia Rheumatica Musculoskeletal 1.04 0.919 – 1.18 0.513 261 2565 all phecode
720 Spinal stenosis Musculoskeletal 1.08 1.05 – 1.12 4.53e-06 3958 28539 all phecode
720.1 Spinal stenosis of lumbar region Musculoskeletal 1.07 1.03 – 1.11 0.00104 2872 23656 all phecode
721 Spondylosis and allied disorders Musculoskeletal 1.05 1.02 – 1.08 0.0027 5509 32391 all phecode
721.1 Spondylosis without myelopathy Musculoskeletal 1.05 1.02 – 1.08 0.00183 5153 31896 all phecode
721.2 Spondylosis with myelopathy Musculoskeletal 1.02 0.954 – 1.1 0.506 867 8629 all phecode
721.8 Other allied disorders of spine Musculoskeletal 0.922 0.812 – 1.05 0.212 262 2600 all phecode
722 Intervertebral disc disorders Musculoskeletal 1.07 1.04 – 1.1 2.63e-06 6284 34317 all phecode
722.1 Displacement of intervertebral disc Musculoskeletal 1.06 1.02 – 1.1 0.00143 3591 31411 all phecode
722.3 Schmorl's nodes Musculoskeletal 1.02 0.847 – 1.22 0.851 126 1248 all phecode
722.6 Degeneration of intervertebral disc Musculoskeletal 1.09 1.05 – 1.12 1.63e-06 3957 30744 all phecode
722.7 Intervertebral disc disorder with myelopathy Musculoskeletal 1.03 0.939 – 1.13 0.538 515 5140 all phecode
722.8 Postlaminectomy syndrome Musculoskeletal 1.11 0.998 – 1.23 0.0543 397 3968 all phecode
722.9 Other and unspecified disc disorder Musculoskeletal 1.06 1.01 – 1.11 0.0127 1932 19288 all phecode
723 Other disorders of cervical region Musculoskeletal 1.09 1.02 – 1.17 0.00824 952 9495 all phecode
723.1 Torticollis Musculoskeletal 1 0.882 – 1.14 0.958 254 2522 all phecode
724 Other and unspecified disorders of back Musculoskeletal 1.06 1.02 – 1.09 0.00132 4130 31954 all phecode
724.1 Disorders of sacrum Musculoskeletal 1.09 1.04 – 1.13 0.000215 2307 21902 all phecode
724.2 Disorders of coccyx Musculoskeletal 1.05 0.95 – 1.16 0.339 426 4215 all phecode
724.8 Other symptoms referable to back Musculoskeletal 1.01 0.946 – 1.08 0.719 931 9295 all phecode
724.9 Other unspecified back disorders Musculoskeletal 1.02 0.966 – 1.08 0.46 1412 14087 all phecode
726 Peripheral enthesopathies and allied syndromes Musculoskeletal 0.996 0.973 – 1.02 0.755 9917 30176 all phecode
726.1 Enthesopathy Musculoskeletal 1.01 0.981 – 1.03 0.589 7507 30106 all phecode
726.2 Synoviopathy Musculoskeletal 1.05 0.983 – 1.12 0.144 1015 9987 all phecode
726.3 Bursitis Musculoskeletal 0.995 0.947 – 1.05 0.847 1829 16722 all phecode
726.4 Calcaneal spur; Exostosis NOS Musculoskeletal 1.01 0.948 – 1.07 0.82 1193 11485 all phecode
727 Other disorders of synovium, tendon, and bursa Musculoskeletal 1.02 0.992 – 1.04 0.187 7425 30105 all phecode
727.1 Synovitis and tenosynovitis Musculoskeletal 1.03 0.994 – 1.07 0.0995 3092 24998 all phecode
727.2 Bursitis disorders Musculoskeletal 0.974 0.88 – 1.08 0.608 419 4112 all phecode
727.4 Ganglion and cyst of synovium, tendon, and bursa Musculoskeletal 0.955 0.904 – 1.01 0.109 1400 13621 all phecode
727.5 Rupture of synovium Musculoskeletal 0.962 0.874 – 1.06 0.422 480 4672 all phecode
727.6 Rupture of tendon, nontraumatic Musculoskeletal 1.03 0.989 – 1.08 0.148 2461 21948 all phecode
727.7 Contracture of tendon (sheath) Musculoskeletal 1.02 0.938 – 1.12 0.61 591 5893 all phecode
727.8 Plica syndrome Musculoskeletal 0.977 0.818 – 1.17 0.798 130 1264 all phecode
728 Disorders of muscle, ligament, and fascia Musculoskeletal 1 0.973 – 1.04 0.786 4546 29473 all phecode
728.1 Muscular calcification and ossification Musculoskeletal 1.17 0.939 – 1.46 0.162 85 843 all phecode
728.2 Laxity of ligament or hypermobility syndrome Musculoskeletal 1.01 0.895 – 1.14 0.895 297 2949 all phecode
728.7 Fasciitis Musculoskeletal 0.995 0.956 – 1.04 0.798 2814 23463 all phecode
728.71
Contracture of palmar fascia [Dupuytren's
Contracture of palmar fascia [Dupuytren's disease]
 Musculoskeletal 0.988 0.892 – 1.09 0.816 419 4138 all phecode
729 Other disorders of soft tissues Musculoskeletal 1.04 1 – 1.08 0.0302 3642 27471 all phecode
729.1 Rheumatism, unspecified and fibrositis Musculoskeletal 1.18 0.918 – 1.51 0.198 74 726 all phecode
729.3 Panniculitis Musculoskeletal 0.893 0.738 – 1.08 0.245 119 1174 all phecode
729.7 Nontraumatic compartment syndrome Musculoskeletal 1.1 0.864 – 1.4 0.437 67 664 all phecode
731
Osteitis deformans and osteopathies associated
Osteitis deformans and osteopathies associated with other disorders classified elsewhere
 Musculoskeletal 0.89 0.771 – 1.03 0.109 210 2091 all phecode
732 Osteochondropathies Musculoskeletal 0.936 0.841 – 1.04 0.221 361 3604 all phecode
732.1 Juvenile osteochondrosis Musculoskeletal 0.936 0.811 – 1.08 0.365 198 1969 all phecode
732.7 Osteochondritis dissecans Musculoskeletal 1.05 0.85 – 1.3 0.646 90 882 all phecode
733 Other disorders of bone and cartilage Musculoskeletal 0.995 0.963 – 1.03 0.749 4543 26941 all phecode
733.2 Cyst of bone Musculoskeletal 0.979 0.846 – 1.13 0.775 190 1900 all phecode
733.4 Aseptic necrosis of bone Musculoskeletal 0.967 0.883 – 1.06 0.471 518 5160 all phecode
733.6 Costochondritis Musculoskeletal 1.02 0.919 – 1.14 0.669 357 3562 all phecode
733.8 Malunion and nonunion of fracture Musculoskeletal 1.07 0.998 – 1.16 0.0554 822 8205 all phecode
733.9 Chondromalacia Musculoskeletal 1.19 0.974 – 1.46 0.0886 96 960 all phecode
735 Acquired foot deformities Musculoskeletal 0.999 0.964 – 1.04 0.962 3417 29622 all phecode
735.1 Flat foot Musculoskeletal 0.929 0.853 – 1.01 0.0856 620 6092 all phecode
735.2 Acquired toe deformities Musculoskeletal 1.01 0.956 – 1.08 0.637 1323 11983 all phecode
735.21 Hammer toe (acquired) Musculoskeletal 1 0.93 – 1.08 0.979 825 7494 all phecode
735.23 Hallux rigidus Musculoskeletal 1.04 0.937 – 1.15 0.467 405 4005 all phecode
735.3 Hallux valgus (Bunion) Musculoskeletal 0.971 0.919 – 1.03 0.286 1470 14295 all phecode
736 Other acquired deformities of limbs Musculoskeletal 1.01 0.966 – 1.05 0.778 2763 26555 all phecode
736.1 Acquired deformities of forearm Musculoskeletal 1.07 0.881 – 1.31 0.486 104 1033 all phecode
736.2 Acquired deformities of finger Musculoskeletal 1.03 0.896 – 1.19 0.66 215 2142 all phecode
736.3 Acquired deformities of hip Musculoskeletal 1.22 0.94 – 1.59 0.133 60 590 all phecode
736.4 Genu valgum or varum (acquired) Musculoskeletal 0.967 0.865 – 1.08 0.56 325 3247 all phecode
736.5 Acquired deformities of knee Musculoskeletal 0.943 0.829 – 1.07 0.377 246 2460 all phecode
736.6 Unequal leg length (acquired) Musculoskeletal 1.01 0.902 – 1.13 0.883 339 3365 all phecode
737 Curvature of spine Musculoskeletal 0.96 0.911 – 1.01 0.132 1566 15543 all phecode
737.1 Kyphosis (acquired) Musculoskeletal 1.01 0.917 – 1.11 0.879 479 4748 all phecode
737.2 Lordosis (acquired) Musculoskeletal 0.973 0.763 – 1.24 0.825 70 700 all phecode
737.3 Kyphoscoliosis and scoliosis Musculoskeletal 0.941 0.886 – 1 0.0499 1203 11982 all phecode
738 Other acquired musculoskeletal deformity Musculoskeletal 0.976 0.935 – 1.02 0.251 2443 24187 all phecode
738.4 Acquired spondylolisthesis Musculoskeletal 1.01 0.948 – 1.08 0.745 1057 10542 all phecode
739 Contracture of joint Musculoskeletal 0.965 0.888 – 1.05 0.399 621 6207 all phecode
740 Osteoarthrosis Musculoskeletal 1.08 1.05 – 1.1 1.67e-12 16169 30268 all phecode
740.1 Osteoarthritis; localized Musculoskeletal 1.05 1.02 – 1.07 0.00151 7005 27422 all phecode
740.11 Osteoarthrosis, localized, primary Musculoskeletal 1.04 1.01 – 1.07 0.00662 6176 26155 all phecode
740.12 Osteoarthrosis, localized, secondary Musculoskeletal 1.07 0.985 – 1.15 0.111 713 7116 all phecode
740.2 Osteoarthrosis, generalized Musculoskeletal 1.02 0.965 – 1.07 0.516 1609 12092 all phecode
740.3
Osteoarthrosis involving more than one site
Osteoarthrosis involving more than one site, but not specified as generalized
 Musculoskeletal 1 0.902 – 1.12 0.944 373 3586 all phecode
740.9 Osteoarthrosis NOS Musculoskeletal 1.08 1.06 – 1.1 1.5e-12 15497 30141 all phecode
741 Symptoms and disorders of the joints Musculoskeletal 1.02 0.996 – 1.05 0.095 8555 35884 all phecode
741.1 Ankylosis of joint Musculoskeletal 0.991 0.868 – 1.13 0.891 245 2445 all phecode
741.2 Stiffness of joint Musculoskeletal 1.04 0.978 – 1.1 0.226 1268 12594 all phecode
741.3 Difficulty in walking Musculoskeletal 1.03 0.986 – 1.07 0.189 2558 23116 all phecode
741.4 Joint effusions Musculoskeletal 1.01 0.965 – 1.05 0.793 2493 24199 all phecode
741.5 Hemarthrosis Musculoskeletal 0.866 0.705 – 1.06 0.171 94 937 all phecode
741.6 Villonodular synovitis Musculoskeletal 1.13 0.885 – 1.44 0.327 68 666 all phecode
742 Derangement of joint, non-traumatic Musculoskeletal 1.03 0.993 – 1.06 0.122 4404 33771 all phecode
742.1 Loose body in joint Musculoskeletal 1.05 0.893 – 1.24 0.537 156 1554 all phecode
742.2
Pathological, developmental or recurrent
Pathological, developmental or recurrent dislocation
 Musculoskeletal 0.944 0.833 – 1.07 0.37 280 2792 all phecode
742.8 Articular cartilage disorder Musculoskeletal 0.981 0.858 – 1.12 0.772 245 2450 all phecode
742.9 Other derangement of joint Musculoskeletal 1.03 0.995 – 1.06 0.096 4107 32972 all phecode
743
Osteoporosis, osteopenia and pathological
Osteoporosis, osteopenia and pathological fracture
 Musculoskeletal 0.998 0.974 – 1.02 0.855 9223 36921 all phecode
743.1 Osteoporosis Musculoskeletal 1.03 0.99 – 1.07 0.158 3712 19477 all phecode
743.11 Osteoporosis NOS Musculoskeletal 1.03 0.989 – 1.07 0.162 3657 19276 all phecode
743.12 Senile osteoporosis Musculoskeletal 0.965 0.89 – 1.05 0.383 703 5804 all phecode
743.13 Other specified osteoporosis Musculoskeletal 1.04 0.928 – 1.17 0.484 321 3141 all phecode
743.2 Pathologic fracture Musculoskeletal 1.01 0.945 – 1.07 0.855 1112 10563 all phecode
743.21 Pathologic fracture of vertebrae Musculoskeletal 1.01 0.92 – 1.11 0.794 475 4629 all phecode
743.22 Pathologic fracture of femur Musculoskeletal 1.08 0.904 – 1.28 0.41 143 1391 all phecode
743.4 Stress fracture Musculoskeletal 0.964 0.869 – 1.07 0.49 407 4046 all phecode
743.9
Osteopenia or other disorder of bone and
Osteopenia or other disorder of bone and cartilage
 Musculoskeletal 0.979 0.953 – 1.01 0.125 6970 35237 all phecode
745 Pain in joint Musculoskeletal 1 0.984 – 1.02 0.827 19848 26918 all phecode
747 Cardiac and circulatory congenital anomalies Congenital Anomalies 1.01 0.965 – 1.05 0.692 2236 22256 all phecode
747.1 Cardiac congenital anomalies Congenital Anomalies 1.03 0.979 – 1.08 0.268 1767 17598 all phecode
747.11 Cardiac shunt/ heart septal defect Congenital Anomalies 0.971 0.895 – 1.05 0.468 650 6497 all phecode
747.12 Valvular heart disease/ heart chambers Congenital Anomalies 1.02 0.946 – 1.1 0.608 751 7480 all phecode
747.13 Congenital anomalies of great vessels Congenital Anomalies 1.08 0.979 – 1.2 0.121 410 4090 all phecode
747.2
Congenital anomalies of peripheral vascular
Congenital anomalies of peripheral vascular system
 Congenital Anomalies 0.973 0.886 – 1.07 0.559 501 5010 all phecode
748 Anomalies of respiratory system, congenital Congenital Anomalies 1.07 0.88 – 1.31 0.49 111 1110 all phecode
749 Congenital anomalies of face and neck Congenital Anomalies 1.03 0.944 – 1.13 0.493 555 5549 all phecode
749.1 Cleft palate Congenital Anomalies 0.997 0.811 – 1.23 0.974 97 970 all phecode
749.2 Congenital anomalies of skull and face bones Congenital Anomalies 0.975 0.796 – 1.2 0.809 105 1041 all phecode
750 Digestive congenital anomalies Congenital Anomalies 0.938 0.875 – 1.01 0.076 893 8919 all phecode
750.1 Upper gastrointestinal congenital anomalies Congenital Anomalies 0.902 0.808 – 1.01 0.0658 366 3655 all phecode
750.11 Esophageal atresia/tracheoesophageal fistula Congenital Anomalies 0.901 0.745 – 1.09 0.285 119 1185 all phecode
750.13 Congenital anomalies of mouth/tongue Congenital Anomalies 0.792 0.644 – 0.974 0.0271 99 982 all phecode
750.14 Congenital anomalies of esophagus Congenital Anomalies 0.955 0.8 – 1.14 0.612 134 1332 all phecode
750.15 Congenital anomalies of stomach Congenital Anomalies 1.06 0.807 – 1.38 0.695 60 593 all phecode
750.2 Lower gastrointestinal congenital anomalies Congenital Anomalies 0.968 0.885 – 1.06 0.483 531 5300 all phecode
750.21 Congenital anomalies of intestine Congenital Anomalies 0.882 0.785 – 0.991 0.0353 313 3129 all phecode
750.22
Congenital anomaly of gallbladder, bile ducts
Congenital anomaly of gallbladder, bile ducts, liver, pancreas
 Congenital Anomalies 1.09 0.946 – 1.25 0.241 222 2214 all phecode
751 Genitourinary congenital anomalies Congenital Anomalies 1.01 0.966 – 1.06 0.615 2008 19975 all phecode
751.1 Congenital anomalies of genital organs Congenital Anomalies 1.05 0.962 – 1.14 0.282 574 5740 all phecode
751.11 Congenital anomalies of female genital organs Congenital Anomalies 1.07 0.963 – 1.19 0.207 384 3840 all phecode
751.12 Congenital anomalies of male genital organs Congenital Anomalies 0.995 0.842 – 1.18 0.957 153 1527 all phecode
751.2 Congenital anomalies of urinary system Congenital Anomalies 0.998 0.944 – 1.06 0.957 1379 13704 all phecode
751.21 Cystic kidney disease Congenital Anomalies 0.938 0.877 – 1 0.0594 976 9685 all phecode
751.22 Other specified congenital anomalies of kidney Congenital Anomalies 1.13 1 – 1.28 0.0462 294 2927 all phecode
751.3 Obstructive genitourinary defect Congenital Anomalies 1.17 1 – 1.37 0.0462 182 1809 all phecode
752 Nervous system congenital anomalies Congenital Anomalies 1.01 0.95 – 1.07 0.743 1133 11313 all phecode
752.1 Neural tube defects Congenital Anomalies 1.01 0.941 – 1.08 0.825 923 9209 all phecode
752.11 Spina bifida Congenital Anomalies 1.02 0.873 – 1.2 0.772 176 1760 all phecode
752.2
Other specified congenital anomalies of nervous
Other specified congenital anomalies of nervous system
 Congenital Anomalies 1.04 0.906 – 1.19 0.591 232 2320 all phecode
753 Congenital anomalies of the eye Congenital Anomalies 0.985 0.852 – 1.14 0.835 207 2051 all phecode
753.1 Congenital cataract and lens anomalies Congenital Anomalies 1.01 0.771 – 1.32 0.937 58 580 all phecode
753.2 Congenital anomalies of posterior segment of eye Congenital Anomalies 0.765 0.58 – 1.01 0.0572 56 546 all phecode
754 Congenital musculoskeletal deformities of spine Congenital Anomalies 1.02 0.958 – 1.08 0.574 1216 12116 all phecode
754.1 Lumbosacral spondylolysis, congenital Congenital Anomalies 1.13 0.956 – 1.34 0.148 135 1333 all phecode
754.2 Spondylolisthesis, congenital Congenital Anomalies 1.01 0.926 – 1.11 0.79 558 5570 all phecode
755 Congenital anomalies of limbs Congenital Anomalies 1.02 0.948 – 1.1 0.576 747 7458 all phecode
755.1 Congenital deformities of feet Congenital Anomalies 1.03 0.919 – 1.15 0.648 368 3663 all phecode
755.4
Congenital anomalies of upper limb, including
Congenital anomalies of upper limb, including shoulder girdle
 Congenital Anomalies 1.09 0.86 – 1.39 0.471 74 740 all phecode
755.6
Other congenital anomalies of lower limb
Other congenital anomalies of lower limb, including pelvic girdle
 Congenital Anomalies 1.04 0.926 – 1.16 0.536 321 3205 all phecode
755.61 Congenital hip dysplasia and deformity Congenital Anomalies 1 0.862 – 1.16 0.999 185 1847 all phecode
756 Other congenital musculoskeletal anomalies Congenital Anomalies 1.02 0.961 – 1.07 0.578 1358 13579 all phecode
756.1 Congenital anomalies of abdominal wall; diaphram Congenital Anomalies 0.968 0.752 – 1.25 0.798 68 680 all phecode
756.2
Pectus and other congenital anomalies of
Pectus and other congenital anomalies of ribs/sternum
 Congenital Anomalies 1.02 0.808 – 1.28 0.875 71 694 all phecode
756.3
Congenital anomalies of muscle, tendon, fascia
Congenital anomalies of muscle, tendon, fascia, and connective tissue
 Congenital Anomalies 0.954 0.854 – 1.07 0.404 335 3346 all phecode
756.5 Congenital osteodystrophies Congenital Anomalies 1 0.939 – 1.07 0.949 1003 10014 all phecode
757 Congenital anomalies of the integument Congenital Anomalies 1 0.901 – 1.11 0.993 401 4001 all phecode
758 Chromosomal anomalies and genetic disorders Congenital Anomalies 0.878 0.755 – 1.02 0.091 185 1845 all phecode
758.1 Chromosomal anomalies Congenital Anomalies 0.907 0.76 – 1.08 0.278 135 1349 all phecode
759 Other and unspecified congenital anomalies Congenital Anomalies 0.956 0.875 – 1.05 0.324 557 5566 all phecode
759.1 Anomalies of endocrine glands, congenital Congenital Anomalies 1.01 0.788 – 1.29 0.954 71 710 all phecode
760 Back pain Symptoms 1.07 1.04 – 1.09 2.28e-10 16037 30719 all phecode
761 Cervicalgia Symptoms 1.06 1.03 – 1.09 1.62e-05 6528 39755 all phecode
763
Thoracic or lumbosacral neuritis or
Thoracic or lumbosacral neuritis or radiculitis, unspecified
 Symptoms 1.04 1 – 1.07 0.0458 3657 32599 all phecode
764 Sciatica Symptoms 1.07 1.03 – 1.11 0.000176 3542 32015 all phecode
765 Cervical radiculitis Symptoms 1.09 1.04 – 1.15 0.000513 1799 17851 all phecode
766 Neuralgia, neuritis, and radiculitis NOS Symptoms 1.07 1.04 – 1.1 9.52e-06 5124 37132 all phecode
767 Cervicocranial/Cervicobrachial syndrome Symptoms 1.04 0.86 – 1.26 0.678 117 1168 all phecode
769 Nonallopathic lesions NEC Symptoms 1.08 1.01 – 1.14 0.0193 1131 11220 all phecode
770 Myalgia and myositis unspecified Symptoms 1.06 1.03 – 1.09 0.000184 5533 34303 all phecode
771 Musculoskeletal symptoms referable to limbs Symptoms 1.01 0.976 – 1.04 0.681 4799 35575 all phecode
771.1 Swelling of limb Symptoms 1.01 0.986 – 1.04 0.332 5743 35539 all phecode
771.2 Cramp of limb Symptoms 1.06 0.999 – 1.13 0.0524 1079 10568 all phecode
772 Symptoms of the muscles Symptoms 0.997 0.953 – 1.04 0.915 2042 20221 all phecode
772.1 Muscular wasting and disuse atrophy Symptoms 1.04 0.935 – 1.15 0.496 422 4199 all phecode
772.2 Spasm of muscle Symptoms 1 0.959 – 1.05 0.933 2299 22726 all phecode
772.3 Muscle weakness Symptoms 1 0.963 – 1.04 0.954 2949 28064 all phecode
772.4 Rhabdomyolysis Symptoms 1.15 0.978 – 1.35 0.0915 159 1572 all phecode
772.6 Facial weakness Symptoms 0.968 0.881 – 1.06 0.502 478 4742 all phecode
780 Hypothermia/Chills Symptoms 1 0.91 – 1.1 0.977 453 4514 all phecode
781
Symptoms involving nervous and musculoskeletal
Symptoms involving nervous and musculoskeletal systems
 Symptoms 1.02 0.982 – 1.06 0.282 2822 26225 all phecode
781.1 Loss of height Symptoms 0.961 0.802 – 1.15 0.665 130 1269 all phecode
781.2 Abnormal posture Symptoms 0.899 0.683 – 1.18 0.445 57 567 all phecode
782.3 Edema Symptoms 1.02 0.99 – 1.05 0.209 5874 36788 all phecode
782.6 Pallor and flushing Symptoms 1.03 0.964 – 1.1 0.375 927 9252 all phecode
783 Fever of unknown origin Symptoms 1.03 1 – 1.06 0.0347 5733 40720 all phecode
783.1 Postprocedural fever Symptoms 1.02 0.903 – 1.15 0.756 300 2992 all phecode
785 Abdominal pain Symptoms 1.02 1 – 1.04 0.036 16458 30297 all phecode
788 Syncope and collapse Symptoms 1 0.97 – 1.04 0.851 3851 35832 all phecode
789 Nausea and vomiting Symptoms 1.04 1.01 – 1.06 0.00132 10568 36098 all phecode
789.1 Persistent vomiting Symptoms 1.09 1.01 – 1.17 0.0288 798 7924 all phecode
790 Nonspecific findings on examination of blood Symptoms 1 0.959 – 1.04 0.979 2363 22690 all phecode
790.1 Elevated sedimentation rate Symptoms 1.01 0.882 – 1.15 0.898 236 2322 all phecode
790.6 Other abnormal blood chemistry Symptoms 1.01 0.988 – 1.04 0.296 7539 37788 all phecode
790.8 Elevated C-reactive protein (CRP) Symptoms 1.1 0.976 – 1.23 0.12 309 3075 all phecode
790.9 Abnormal arterial blood gases Symptoms 1.1 0.94 – 1.3 0.23 155 1521 all phecode
791 Gangrene Symptoms 1.07 0.955 – 1.2 0.243 313 3115 all phecode
792
Abnormal Papanicolaou smear of cervix and
Abnormal Papanicolaou smear of cervix and cervical HPV
 Genitourinary 0.968 0.929 – 1.01 0.12 2820 14872 all phecode
792.1
Papanicolaou smear of cervix or vagina with
Papanicolaou smear of cervix or vagina with atypical squamous cells
 Genitourinary 0.977 0.917 – 1.04 0.461 1100 9861 all phecode
794
Abnormal results of other function studies
Abnormal results of other function studies (bladder, pancreas, placenta, spleen, etc)
 Symptoms 0.983 0.898 – 1.08 0.711 515 5133 all phecode
795
Other and nonspecific abnormal cytological
Other and nonspecific abnormal cytological, histological and immunological findings
 Symptoms 0.959 0.917 – 1 0.0636 2182 20242 all phecode
795.8 Abnormal tumor markers Symptoms 0.975 0.927 – 1.02 0.317 1745 15551 all phecode
795.81 Elevated carcinoembryonic antigen [CEA] Symptoms 1.04 0.793 – 1.36 0.79 61 605 all phecode
795.82 Elevated cancer antigen 125 [CA 125] Symptoms 0.831 0.719 – 0.961 0.0125 201 2000 all phecode
796 Elevated prostate specific antigen [PSA] Genitourinary 0.991 0.944 – 1.04 0.727 2125 9930 all phecode
797 Shock Symptoms 0.99 0.91 – 1.08 0.824 605 6050 all phecode
797.1 Cardiogenic shock Symptoms 0.945 0.828 – 1.08 0.402 242 2420 all phecode
798 Malaise and fatigue Symptoms 1.02 1 – 1.05 0.0346 11539 35196 all phecode
798.1 Chronic fatigue syndrome Symptoms 1.03 0.984 – 1.09 0.182 1823 17795 all phecode
800 Fracture of lower limb Injuries & Poisonings 0.961 0.92 – 1 0.0681 2344 22951 all phecode
800.1 Fracture of neck of femur Injuries & Poisonings 0.982 0.896 – 1.08 0.705 512 4961 all phecode
800.2 Fracture of unspecified part of femur Injuries & Poisonings 0.977 0.901 – 1.06 0.57 670 6582 all phecode
800.3 Fracture of tibia and fibula Injuries & Poisonings 0.932 0.869 – 0.999 0.0471 898 8966 all phecode
800.4 Fracture of patella Injuries & Poisonings 1.03 0.918 – 1.15 0.653 346 3456 all phecode
801 Fracture of ankle and foot Injuries & Poisonings 0.971 0.93 – 1.01 0.176 2358 22645 all phecode
801.1 Fracture of foot Injuries & Poisonings 0.916 0.861 – 0.975 0.00564 1120 11178 all phecode
802 Fracture of pelvis Injuries & Poisonings 0.99 0.89 – 1.1 0.848 380 3765 all phecode
803 Fracture of upper limb Injuries & Poisonings 0.944 0.902 – 0.989 0.015 2051 20360 all phecode
803.1 Fracture of humerus Injuries & Poisonings 0.945 0.875 – 1.02 0.152 734 7322 all phecode
803.2 Fracture of radius and ulna Injuries & Poisonings 0.917 0.861 – 0.976 0.00661 1112 11075 all phecode
803.21 Colles' fracture Injuries & Poisonings 0.944 0.835 – 1.07 0.363 291 2904 all phecode
803.3 Fracture of clavicle or scapula Injuries & Poisonings 0.923 0.842 – 1.01 0.086 514 5140 all phecode
804 Fracture of hand or wrist Injuries & Poisonings 0.967 0.918 – 1.02 0.198 1628 16042 all phecode
805
Fracture of vertebral column without mention of
Fracture of vertebral column without mention of spinal cord injury
 Injuries & Poisonings 0.985 0.93 – 1.04 0.595 1336 13242 all phecode
807 Fracture of ribs Injuries & Poisonings 0.964 0.89 – 1.04 0.367 683 6815 all phecode
809 Fracture of unspecified bones Injuries & Poisonings 0.972 0.936 – 1.01 0.152 2941 28633 all phecode
816 Cerebral laceration and contusion Injuries & Poisonings 0.862 0.652 – 1.14 0.296 54 531 all phecode
817 Concussion Injuries & Poisonings 1.07 1.01 – 1.15 0.0349 1018 10149 all phecode
818 Intracranial hemorrhage (injury) Injuries & Poisonings 1.02 0.91 – 1.15 0.695 311 3104 all phecode
818.1 Subdural hemorrhage (injury) Injuries & Poisonings 1.03 0.828 – 1.28 0.79 90 895 all phecode
818.2 Subarachnoid hemorrhage (injury) Injuries & Poisonings 1.01 0.822 – 1.25 0.907 97 970 all phecode
819
Skull and face fracture and other intercranial
Skull and face fracture and other intercranial injury
 Injuries & Poisonings 1.01 0.964 – 1.05 0.747 2287 22671 all phecode
830 Dislocation Injuries & Poisonings 0.98 0.948 – 1.01 0.244 3862 34720 all phecode
835 Internal derangement of knee Injuries & Poisonings 0.974 0.932 – 1.02 0.248 2231 21628 all phecode
836 Traumatic arthropathy Injuries & Poisonings 0.971 0.883 – 1.07 0.539 496 4954 all phecode
840 Sprains and strains Injuries & Poisonings 0.989 0.965 – 1.01 0.38 7838 37998 all phecode
840.1 Muscle/tendon sprain Injuries & Poisonings 1.05 0.956 – 1.14 0.326 537 5356 all phecode
840.2 Rotator cuff (capsule) sprain Injuries & Poisonings 1.07 1.01 – 1.12 0.013 1640 16263 all phecode
840.3 Joint/ligament sprain Injuries & Poisonings 0.961 0.924 – 0.999 0.0464 2875 24879 all phecode
841 Sprains and strains of back and neck Injuries & Poisonings 0.952 0.903 – 1 0.0689 1583 15592 all phecode
842 Other sprains and strains Injuries & Poisonings 1.01 0.951 – 1.06 0.841 1407 13924 all phecode
850 Hemorrhage or hematoma complicating a procedure Injuries & Poisonings 1.01 0.969 – 1.06 0.55 2072 20649 all phecode
851
Complications of transplants and reattached
Complications of transplants and reattached limbs
 Injuries & Poisonings 1.08 1.04 – 1.12 0.000178 2982 27545 all phecode
853 Complication of colostomy or enterostomy Injuries & Poisonings 1.07 0.971 – 1.18 0.174 460 4600 all phecode
854
Complications of cardiac/vascular device
Complications of cardiac/vascular device, implant, and graft
 Injuries & Poisonings 1.06 1.01 – 1.11 0.00988 1985 19675 all phecode
855
Complication of nervous system device, implant
Complication of nervous system device, implant, and graft
 Injuries & Poisonings 1.12 0.982 – 1.27 0.094 264 2640 all phecode
856
Vascular complications of surgery and medical
Vascular complications of surgery and medical procedures
 Injuries & Poisonings 1 0.886 – 1.13 0.994 293 2929 all phecode
857
Mechanical complication of unspecified
Mechanical complication of unspecified genitourinary device, implant, and graft
 Injuries & Poisonings 1.06 0.997 – 1.12 0.0618 1310 13087 all phecode
858 Complication of internal orthopedic device Injuries & Poisonings 1.06 1.01 – 1.1 0.0163 2213 21944 all phecode
859
Complication due to other implant and internal
Complication due to other implant and internal device
 Injuries & Poisonings 1.05 1 – 1.1 0.0365 2110 21070 all phecode
860 Bone marrow or stem cell transplant Neoplasms 0.847 0.723 – 0.993 0.0403 166 1660 all phecode
870 Open wounds of head; neck; and trunk Injuries & Poisonings 1.01 0.975 – 1.04 0.666 4117 36734 all phecode
870.1 Open wound or laceration of eye or eyelid Injuries & Poisonings 1.1 0.947 – 1.27 0.218 204 2026 all phecode
870.2 Open wound of ear Injuries & Poisonings 0.827 0.698 – 0.98 0.0286 144 1437 all phecode
870.3 Other open wound of head and face Injuries & Poisonings 0.959 0.906 – 1.02 0.151 1346 13301 all phecode
870.4 Open wound of nose and sinus Injuries & Poisonings 0.899 0.776 – 1.04 0.154 207 2057 all phecode
870.5 Open wound of lip and mouth Injuries & Poisonings 0.982 0.864 – 1.12 0.787 275 2724 all phecode
870.6 Open wound of neck Injuries & Poisonings 1.1 0.953 – 1.27 0.189 214 2128 all phecode
870.8 Open wound of genital organs Injuries & Poisonings 0.987 0.832 – 1.17 0.879 144 1440 all phecode
871 Open wounds of extremities Injuries & Poisonings 1.02 0.984 – 1.06 0.292 3530 32903 all phecode
871.1 Open wound of hand except finger(s) Injuries & Poisonings 1.01 0.928 – 1.11 0.772 572 5701 all phecode
871.2 Open wound of finger(s) Injuries & Poisonings 1 0.939 – 1.07 0.908 984 9772 all phecode
871.3 Open wound of foot except toe(s) alone Injuries & Poisonings 1.06 0.968 – 1.17 0.198 490 4843 all phecode
871.4 Open wound of toe(s) Injuries & Poisonings 0.938 0.831 – 1.06 0.302 295 2921 all phecode
872 Traumatic amputation Injuries & Poisonings 1.07 0.977 – 1.17 0.15 551 5477 all phecode
874 Complication of amputation stump Injuries & Poisonings 1.19 1.02 – 1.39 0.0271 170 1697 all phecode
875 Non-healing surgical wound Injuries & Poisonings 1.06 0.968 – 1.15 0.22 572 5720 all phecode
876
Posttraumatic wound infection not elsewhere
Posttraumatic wound infection not elsewhere classified
 Injuries & Poisonings 1.14 1.06 – 1.23 0.000507 802 8003 all phecode
907 Injuries to the nervous system Injuries & Poisonings 1.03 0.96 – 1.09 0.461 1010 10096 all phecode
910 Superficial injury, infected Injuries & Poisonings 0.961 0.796 – 1.16 0.683 119 1161 all phecode
911 Blister Injuries & Poisonings 1.06 0.939 – 1.19 0.348 302 2996 all phecode
912 Insect bite Injuries & Poisonings 0.976 0.888 – 1.07 0.608 492 4886 all phecode
913 Toxic effect of venom Injuries & Poisonings 0.956 0.853 – 1.07 0.436 337 3326 all phecode
916 Contusion Injuries & Poisonings 1.03 0.996 – 1.06 0.0867 4296 38033 all phecode
930 Allergic reaction to food Injuries & Poisonings 1.04 0.962 – 1.12 0.333 763 7596 all phecode
931
Contact dermatitis and other eczema due to
Contact dermatitis and other eczema due to plants [except food]
 Dermatologic 0.941 0.87 – 1.02 0.128 714 7072 all phecode
938 Dermatitis due to solar radiation Dermatologic 0.944 0.916 – 0.972 0.000126 5567 29098 all phecode
938.1 Acute dermatitis due to solar radiation Dermatologic 0.967 0.838 – 1.12 0.649 217 2164 all phecode
938.2 Chronic dermatitis due to solar radiation Dermatologic 0.943 0.915 – 0.972 0.000139 5307 28656 all phecode
939
Atopic/contact dermatitis due to other or
Atopic/contact dermatitis due to other or unspecified
 Dermatologic 0.966 0.94 – 0.992 0.0121 6704 32389 all phecode
939.1 Contact and allergic dermatitis of eyelid Dermatologic 1.03 0.83 – 1.28 0.797 91 870 all phecode
941 Adverse reaction to serum or vaccine Injuries & Poisonings 1.29 1.11 – 1.5 0.001 188 1880 all phecode
942 Infusion and transfusion reaction Injuries & Poisonings 1.07 0.944 – 1.22 0.284 269 2688 all phecode
946 Anaphylactic shock NOS Injuries & Poisonings 0.953 0.868 – 1.05 0.306 500 4940 all phecode
947 Urticaria Dermatologic 1.03 0.965 – 1.09 0.423 1177 11454 all phecode
949 Allergies, other Injuries & Poisonings 0.996 0.971 – 1.02 0.79 7251 32350 all phecode
952
Spinal cord injury without evidence of spinal
Spinal cord injury without evidence of spinal bone injury
 Injuries & Poisonings 1.03 0.942 – 1.14 0.477 494 4940 all phecode
957 Injury to other and unspecified nerves Injuries & Poisonings 1.14 0.952 – 1.36 0.156 136 1352 all phecode
958
Certain early complications of trauma or
Certain early complications of trauma or procedure
 Injuries & Poisonings 1.08 1.02 – 1.14 0.0142 1217 12158 all phecode
958.1 Postoperative shock Injuries & Poisonings 1.03 0.873 – 1.21 0.748 169 1688 all phecode
958.2 Traumatic and surgical subcutaneous emphysema Injuries & Poisonings 1.13 0.929 – 1.38 0.217 114 1140 all phecode
960 Poisoning by antibiotics Injuries & Poisonings 1.01 0.969 – 1.05 0.611 2479 22087 all phecode
960.1
Adverse effects of antibacterials (not
Adverse effects of antibacterials (not penicillins)
 Injuries & Poisonings 1.06 0.949 – 1.18 0.3 342 3403 all phecode
960.2 Allergy/adverse effect of penicillin Injuries & Poisonings 1.01 0.963 – 1.07 0.589 1636 16005 all phecode
961 Poisoning by other anti-infectives Injuries & Poisonings 1.12 1.03 – 1.23 0.0115 528 5234 all phecode
961.1 Poisoning/allergy of sulfonamides Injuries & Poisonings 1.08 1.02 – 1.16 0.0128 1065 10347 all phecode
962 Poisoning by hormones and synthetic substitutes Injuries & Poisonings 1.07 0.999 – 1.16 0.0543 803 7976 all phecode
962.1
Adrenal cortical steroids causing adverse
Adrenal cortical steroids causing adverse effects in therapeutic use
 Injuries & Poisonings 1.01 0.909 – 1.12 0.859 379 3782 all phecode
962.2
Insulins and antidiabetic agents causing
Insulins and antidiabetic agents causing adverse effects in therapeutic use
 Injuries & Poisonings 1.04 0.81 – 1.34 0.745 62 612 all phecode
962.3
Hormones and synthetic substitutes causing
Hormones and synthetic substitutes causing adverse effects in therapeutic use
 Injuries & Poisonings 1.13 1.03 – 1.24 0.012 478 4773 all phecode
963 Poisoning by primarily systemic agents Injuries & Poisonings 0.98 0.94 – 1.02 0.343 2533 24531 all phecode
963.1
Antineoplastic and immunosuppressive drugs
Antineoplastic and immunosuppressive drugs causing adverse effects
 Injuries & Poisonings 0.981 0.94 – 1.02 0.361 2469 24057 all phecode
964
Poisoning by agents primarily affecting blood
Poisoning by agents primarily affecting blood constituents
 Injuries & Poisonings 0.972 0.9 – 1.05 0.46 743 7337 all phecode
964.1 Anticoagulants causing adverse effects Injuries & Poisonings 0.98 0.907 – 1.06 0.617 712 7027 all phecode
965
Poisoning by analgesics, antipyretics, and
Poisoning by analgesics, antipyretics, and antirheumatics
 Injuries & Poisonings 1.1 1.03 – 1.19 0.00565 864 8601 all phecode
965.1
Opiates and related narcotics causing adverse
Opiates and related narcotics causing adverse effects in therapeutic use
 Injuries & Poisonings 1.07 1.01 – 1.13 0.0161 1469 14402 all phecode
965.3
Salicylates causing adverse effects in
Salicylates causing adverse effects in therapeutic use
 Injuries & Poisonings 0.949 0.787 – 1.14 0.586 119 1182 all phecode
966
Poisoning by anticonvulsants and
Poisoning by anticonvulsants and anti-Parkinsonism drugs
 Injuries & Poisonings 1.28 1.05 – 1.56 0.0143 103 1006 all phecode
967
Adverse effects of sedatives or other central
Adverse effects of sedatives or other central nervous system depressants and anesthetics
 Injuries & Poisonings 1.05 0.991 – 1.11 0.0967 1254 12464 all phecode
969 Poisoning by psychotropic agents Injuries & Poisonings 1.25 1.1 – 1.41 0.000513 281 2797 all phecode
971
Poisoning by drugs primarily affecting the
Poisoning by drugs primarily affecting the autonomic nervous system
 Injuries & Poisonings 0.93 0.728 – 1.19 0.565 67 643 all phecode
972
Poisoning by agents primarily affecting the
Poisoning by agents primarily affecting the cardiovascular system
 Injuries & Poisonings 0.971 0.858 – 1.1 0.634 288 2858 all phecode
972.1
Cardiac rhythm regulators causing adverse
Cardiac rhythm regulators causing adverse effects in therapeutic use
 Injuries & Poisonings 0.748 0.59 – 0.947 0.0157 80 776 all phecode
972.6 Antihypertensive agents causing adverse effects Injuries & Poisonings 1.04 0.848 – 1.27 0.718 104 1034 all phecode
974
Poisoning by water, mineral, and uric acid
Poisoning by water, mineral, and uric acid metabolism drugs
 Injuries & Poisonings 0.94 0.778 – 1.14 0.519 113 1130 all phecode
975
Poisoning by agents primarily acting on the
Poisoning by agents primarily acting on the smooth and skeletal muscles and respiratory system
 Injuries & Poisonings 1.23 0.979 – 1.56 0.075 81 810 all phecode
976
Poisoning by agents primarily affecting skin &
Poisoning by agents primarily affecting skin & mucous membrane, ophthalmological, otorhinolaryngological, & dental drugs
 Injuries & Poisonings 1.01 0.796 – 1.29 0.927 71 703 all phecode
977 Personal history of allergy to medicinal agents Injuries & Poisonings 1.07 1.02 – 1.13 0.00672 1763 16599 all phecode
979 Adverse drug events and drug allergies Injuries & Poisonings 1.03 0.992 – 1.07 0.131 3448 30885 all phecode
980
Encounter for long-term (current) use of
Encounter for long-term (current) use of antibiotics
 Infectious Diseases 0.974 0.922 – 1.03 0.355 1391 13877 all phecode
985 Toxic effect of other metals Injuries & Poisonings 0.973 0.744 – 1.27 0.841 57 564 all phecode
989
Toxic effect of other substances, chiefly
Toxic effect of other substances, chiefly nonmedicinal as to source
 Injuries & Poisonings 0.996 0.83 – 1.2 0.97 129 1275 all phecode
990 Effects radiation NOS Injuries & Poisonings 0.996 0.963 – 1.03 0.802 3927 31223 all phecode
994 Sepsis and SIRS Injuries & Poisonings 1.05 1 – 1.09 0.0442 2192 21710 all phecode
994.1 Systemic inflammatory response syndrome (SIRS) Injuries & Poisonings 1.02 0.906 – 1.16 0.7 291 2910 all phecode
994.2 Sepsis Injuries & Poisonings 1.06 1.01 – 1.11 0.0173 2086 20666 all phecode
994.21 Septic shock Injuries & Poisonings 1.03 0.95 – 1.12 0.463 627 6260 all phecode
008 Intestinal infection Infectious Diseases 0.98 0.927 – 1.04 0.482 1323 20134 exclusion phecode
008.5 Bacterial enteritis Infectious Diseases 0.998 0.915 – 1.09 0.956 561 8894 exclusion phecode
008.52 Intestinal infection due to C. difficile Infectious Diseases 1.01 0.92 – 1.12 0.785 451 7060 exclusion phecode
008.6 Viral Enteritis Infectious Diseases 1 0.893 – 1.13 0.956 301 5242 exclusion phecode
010 Tuberculosis Infectious Diseases 0.927 0.768 – 1.12 0.43 124 1680 exclusion phecode
031 Diseases due to other mycobacteria Infectious Diseases 0.834 0.6 – 1.16 0.278 33 578 exclusion phecode
038 Septicemia Infectious Diseases 1.09 1.03 – 1.16 0.00435 1167 16821 exclusion phecode
038.1 Gram negative septicemia Infectious Diseases 1.1 0.968 – 1.25 0.143 248 3793 exclusion phecode
038.2 Gram positive septicemia Infectious Diseases 1.28 1.05 – 1.55 0.0129 105 1600 exclusion phecode
038.3 Bacteremia Infectious Diseases 1.1 1 – 1.2 0.0453 520 8118 exclusion phecode
041 Bacterial infection NOS Infectious Diseases 1.08 1.04 – 1.12 6.42e-05 2956 27240 exclusion phecode
041.1 Staphylococcus infections Infectious Diseases 1.12 1.04 – 1.2 0.00207 821 11692 exclusion phecode
041.11 Methicillin sensitive Staphylococcus aureus Infectious Diseases 1.11 0.999 – 1.22 0.052 402 6263 exclusion phecode
041.12 Methicillin resistant Staphylococcus aureus Infectious Diseases 1.1 0.989 – 1.22 0.0785 371 5403 exclusion phecode
041.2 Streptococcus infection Infectious Diseases 1.08 1 – 1.16 0.039 824 11096 exclusion phecode
041.21 Rheumatic fever / chorea Infectious Diseases 1.13 0.946 – 1.34 0.179 141 1714 exclusion phecode
041.4 E. coli Infectious Diseases 1.06 0.97 – 1.15 0.204 557 7980 exclusion phecode
041.8 H. pylori Infectious Diseases 0.999 0.835 – 1.2 0.993 129 1745 exclusion phecode
041.9 Infection with drug-resistant microorganisms Infectious Diseases 1.07 0.912 – 1.25 0.409 167 2674 exclusion phecode
053 Herpes zoster Infectious Diseases 1.03 0.95 – 1.11 0.519 706 10715 exclusion phecode
053.1 Herpes zoster with nervous system complications Infectious Diseases 1.14 0.922 – 1.41 0.229 90 1509 exclusion phecode
054 Herpes simplex Infectious Diseases 0.923 0.859 – 0.992 0.03 821 11419 exclusion phecode
070 Viral hepatitis Infectious Diseases 1.08 0.977 – 1.19 0.135 461 5738 exclusion phecode
070.1 Viral hepatitis A Infectious Diseases 0.835 0.625 – 1.12 0.223 45 595 exclusion phecode
070.2 Viral hepatitis B Infectious Diseases 1.05 0.87 – 1.27 0.61 115 1479 exclusion phecode
070.3 Viral hepatitis C Infectious Diseases 1.15 1.02 – 1.29 0.0248 304 3657 exclusion phecode
070.4 Chronic hepatitis Infectious Diseases 0.983 0.804 – 1.2 0.865 98 1333 exclusion phecode
070.9 Hepatitis NOS Infectious Diseases 1.02 0.942 – 1.11 0.575 601 7868 exclusion phecode
071 Human immunodeficiency virus [HIV] disease Infectious Diseases 1 0.78 – 1.29 0.984 64 986 exclusion phecode
071.1 HIV infection, symptomatic Infectious Diseases 0.99 0.736 – 1.33 0.947 48 792 exclusion phecode
078 Viral warts & HPV Infectious Diseases 0.913 0.868 – 0.96 0.000398 1684 21751 exclusion phecode
079 Viral infection Infectious Diseases 0.947 0.912 – 0.983 0.00415 3202 25705 exclusion phecode
079.1 Varicella infection Infectious Diseases 0.924 0.881 – 0.969 0.00121 1873 22609 exclusion phecode
079.2 Infectious mononucleosis Infectious Diseases 1.03 0.88 – 1.21 0.683 158 2153 exclusion phecode
079.9 Viremia, NOS Infectious Diseases 1 0.904 – 1.11 0.962 376 6036 exclusion phecode
080 Postoperative infection Infectious Diseases 1.07 1.01 – 1.13 0.019 1426 17558 exclusion phecode
081
Infection/inflammation of internal prosthetic
Infection/inflammation of internal prosthetic device; implant; and graft
 Infectious Diseases 1.1 1.02 – 1.18 0.0106 792 10718 exclusion phecode
090
Sexually transmitted infections (not HIV or
Sexually transmitted infections (not HIV or hepatitis)
 Infectious Diseases 0.941 0.859 – 1.03 0.191 508 6662 exclusion phecode
110 Dermatophytosis / Dermatomycosis Infectious Diseases 0.925 0.876 – 0.977 0.00479 1452 21042 exclusion phecode
110.1 Dermatophytosis Infectious Diseases 0.903 0.853 – 0.956 0.000486 1296 18977 exclusion phecode
110.11 Dermatophytosis of nail Infectious Diseases 0.895 0.831 – 0.963 0.0029 785 11411 exclusion phecode
110.12 Althete's foot Infectious Diseases 0.875 0.783 – 0.977 0.0175 341 5410 exclusion phecode
110.13 Dermatophytosis of the body Infectious Diseases 0.911 0.813 – 1.02 0.11 313 5432 exclusion phecode
110.2 Dermatomycoses Infectious Diseases 1.03 0.887 – 1.19 0.715 194 2815 exclusion phecode
112 Candidiasis Infectious Diseases 1.01 0.964 – 1.06 0.612 1729 21852 exclusion phecode
112.3 Candidiasis of skin and nails Infectious Diseases 1.01 0.889 – 1.15 0.87 248 4710 exclusion phecode
117 Mycoses Infectious Diseases 0.982 0.867 – 1.11 0.78 267 4323 exclusion phecode
117.1 Histoplasmosis Infectious Diseases 0.933 0.685 – 1.27 0.661 41 539 exclusion phecode
117.4 Aspergillosis Infectious Diseases 0.94 0.716 – 1.23 0.654 56 1005 exclusion phecode
130 Spirochetal infection Infectious Diseases 0.946 0.758 – 1.18 0.625 78 1157 exclusion phecode
130.1 Lyme disease Infectious Diseases 0.978 0.755 – 1.27 0.869 56 804 exclusion phecode
131 Protozoan infection Infectious Diseases 1.26 0.866 – 1.83 0.228 27 447 exclusion phecode
132 Infestation (lice, mites) Infectious Diseases 0.824 0.664 – 1.02 0.0785 84 1348 exclusion phecode
134 Helminthiases Infectious Diseases 0.872 0.63 – 1.21 0.409 38 535 exclusion phecode
134.1 Intestinal helminthiases Infectious Diseases 0.88 0.562 – 1.38 0.575 19 330 exclusion phecode
136 Other infectious and parasitic diseases Infectious Diseases 1.03 0.98 – 1.08 0.236 1693 22166 exclusion phecode
145 Cancer of mouth Neoplasms 1.02 0.959 – 1.09 0.506 1084 9441 exclusion phecode
145.1 Cancer of lip Neoplasms 0.936 0.697 – 1.26 0.659 56 483 exclusion phecode
145.2 Cancer of tongue Neoplasms 1.05 0.954 – 1.16 0.31 473 4129 exclusion phecode
145.3 Cancer of major salivary glands Neoplasms 0.918 0.81 – 1.04 0.183 277 2386 exclusion phecode
145.4 Cancer of the gums Neoplasms 1.01 0.835 – 1.22 0.919 121 1079 exclusion phecode
145.5 Cancer of the mouth floor Neoplasms 1.22 1.03 – 1.44 0.0217 160 1323 exclusion phecode
149 Cancer of larynx, pharynx, nasal cavities Neoplasms 1 0.936 – 1.07 0.96 931 8211 exclusion phecode
149.1 Cancer of oropharynx Neoplasms 1.17 1.02 – 1.34 0.0232 248 2185 exclusion phecode
149.2 Cancer of nasopharynx Neoplasms 0.982 0.754 – 1.28 0.893 58 638 exclusion phecode
149.3 Cancer of hypopharynx Neoplasms 1 0.757 – 1.32 0.999 60 503 exclusion phecode
149.4 Cancer of larynx Neoplasms 1.07 0.943 – 1.21 0.307 294 2467 exclusion phecode
149.5
Hx of malignant neoplasm of oral cavity and
Hx of malignant neoplasm of oral cavity and pharynx
 Neoplasms 1.01 0.906 – 1.12 0.87 379 3539 exclusion phecode
149.9 Cancer of of nasal cavities Neoplasms 0.921 0.785 – 1.08 0.309 163 1528 exclusion phecode
150 Cancer of esophagus Neoplasms 0.944 0.833 – 1.07 0.368 271 2894 exclusion phecode
151 Cancer of stomach Neoplasms 1.08 0.963 – 1.21 0.187 330 3310 exclusion phecode
153 Colorectal cancer Neoplasms 0.981 0.915 – 1.05 0.583 894 10083 exclusion phecode
153.2 Colon cancer Neoplasms 0.985 0.912 – 1.06 0.707 710 8069 exclusion phecode
153.3
Malignant neoplasm of rectum, rectosigmoid
Malignant neoplasm of rectum, rectosigmoid junction, and anus
 Neoplasms 0.946 0.863 – 1.04 0.24 511 5704 exclusion phecode
155 Cancer of liver and intrahepatic bile duct Neoplasms 1.03 0.916 – 1.16 0.634 322 3430 exclusion phecode
155.1 Malignant neoplasm of liver, primary Neoplasms 1.05 0.91 – 1.21 0.504 214 2300 exclusion phecode
157 Pancreatic cancer Neoplasms 0.966 0.863 – 1.08 0.551 334 3326 exclusion phecode
158
Neoplasm of unspecified nature of digestive
Neoplasm of unspecified nature of digestive system
 Neoplasms 1.06 0.992 – 1.14 0.0859 902 10619 exclusion phecode
159
Malignant neoplasm of other and ill-defined
Malignant neoplasm of other and ill-defined sites within the digestive organs and peritoneum
 Neoplasms 0.984 0.925 – 1.05 0.61 1125 12098 exclusion phecode
159.2
Malignant neoplasm of small intestine
Malignant neoplasm of small intestine, including duodenum
 Neoplasms 1.02 0.858 – 1.22 0.788 136 1439 exclusion phecode
159.3
Malignant neoplasm of gallbladder and
Malignant neoplasm of gallbladder and extrahepatic bile ducts
 Neoplasms 1.03 0.843 – 1.26 0.776 110 1027 exclusion phecode
159.4
Malignant neoplasm of retroperitoneum and
Malignant neoplasm of retroperitoneum and peritoneum
 Neoplasms 0.92 0.792 – 1.07 0.281 189 2019 exclusion phecode
164 Cancer of intrathoracic organs Neoplasms 0.897 0.722 – 1.11 0.325 85 861 exclusion phecode
165 Cancer within the respiratory system Neoplasms 1.03 0.963 – 1.11 0.359 860 8575 exclusion phecode
165.1 Cancer of bronchus; lung Neoplasms 1.01 0.935 – 1.1 0.729 655 6765 exclusion phecode
170 Cancer of bone and connective tissue Neoplasms 0.992 0.935 – 1.05 0.782 1253 11699 exclusion phecode
170.1 Bone cancer Neoplasms 0.983 0.898 – 1.08 0.703 536 5053 exclusion phecode
170.2 Cancer of connective tissue Neoplasms 0.982 0.915 – 1.05 0.602 886 8252 exclusion phecode
172 Skin cancer Neoplasms 0.969 0.94 – 1 0.0471 5639 22175 exclusion phecode
172.1 Melanomas of skin, dx or hx Neoplasms 0.946 0.912 – 0.982 0.0037 3453 19848 exclusion phecode
172.11 Melanomas of skin Neoplasms 0.949 0.908 – 0.992 0.0217 2253 16460 exclusion phecode
172.2 Other non-epithelial cancer of skin Neoplasms 0.974 0.942 – 1.01 0.132 4509 20017 exclusion phecode
172.21 Basal cell carcinoma Neoplasms 0.933 0.891 – 0.977 0.00325 2197 15387 exclusion phecode
172.22 Squamous cell carcinoma Neoplasms 0.994 0.94 – 1.05 0.836 1501 11286 exclusion phecode
172.3 Carcinoma in situ of skin Neoplasms 0.95 0.884 – 1.02 0.157 869 7858 exclusion phecode
173 Neoplasm of uncertain behavior of skin Neoplasms 0.964 0.903 – 1.03 0.27 1014 12290 exclusion phecode
174 Breast cancer Neoplasms 0.963 0.918 – 1.01 0.126 2071 10900 exclusion phecode
174.1 Breast cancer [female] Neoplasms 0.971 0.924 – 1.02 0.236 1984 10409 exclusion phecode
174.11 Malignant neoplasm of female breast Neoplasms 0.976 0.929 – 1.03 0.338 1952 10361 exclusion phecode
174.3 Neoplasm of uncertain behavior of breast Neoplasms 0.983 0.822 – 1.17 0.85 134 1625 exclusion phecode
175 Acquired absence of breast Neoplasms 0.927 0.851 – 1.01 0.0835 576 6534 exclusion phecode
180 Cervical cancer and dysplasia Neoplasms 1 0.936 – 1.07 0.936 905 8977 exclusion phecode
180.1 Cervical cancer Neoplasms 1.01 0.905 – 1.13 0.832 340 3596 exclusion phecode
180.3
Cervical intraepithelial neoplasia [CIN]
Cervical intraepithelial neoplasia [CIN] [Cervical dysplasia]
 Neoplasms 0.988 0.911 – 1.07 0.78 641 7007 exclusion phecode
182 Malignant neoplasm of uterus Neoplasms 1 0.913 – 1.1 0.973 496 5208 exclusion phecode
184 Cancer of other female genital organs Neoplasms 0.899 0.833 – 0.97 0.00598 751 7884 exclusion phecode
184.1
Malignant neoplasm of ovary and other uterine
Malignant neoplasm of ovary and other uterine adnexa
 Neoplasms 0.868 0.78 – 0.965 0.00865 385 3839 exclusion phecode
184.11 Malignant neoplasm of ovary Neoplasms 0.869 0.769 – 0.982 0.0248 292 2888 exclusion phecode
184.2
Cancer of other female genital organs
Cancer of other female genital organs (excluding uterus and ovary)
 Neoplasms 0.951 0.852 – 1.06 0.37 362 4068 exclusion phecode
185 Cancer of prostate Neoplasms 1.01 0.962 – 1.07 0.595 1925 6736 exclusion phecode
187 Cancer of other male genital organs Neoplasms 1.05 0.915 – 1.21 0.476 219 2212 exclusion phecode
187.1
Malignant neoplasm of unspecified male genital
Malignant neoplasm of unspecified male genital organ
 Neoplasms 1.12 0.881 – 1.43 0.353 80 710 exclusion phecode
187.2 Malignant neoplasm of testis Neoplasms 0.992 0.82 – 1.2 0.938 119 1243 exclusion phecode
187.8
Neoplasm of uncertain behavior of male genital
Neoplasm of uncertain behavior of male genital organs
 Neoplasms 0.99 0.682 – 1.44 0.96 29 352 exclusion phecode
189
Cancer of urinary organs (incl. kidney and
Cancer of urinary organs (incl. kidney and bladder)
 Neoplasms 1.04 0.996 – 1.1 0.0742 1965 15022 exclusion phecode
189.1 Cancer of kidney and renal pelvis Neoplasms 1.04 0.973 – 1.11 0.238 965 9210 exclusion phecode
189.11 Malignant neoplasm of kidney, except pelvis Neoplasms 1.02 0.953 – 1.1 0.51 846 8060 exclusion phecode
189.12 Malignant neoplasm of renal pelvis Neoplasms 1.01 0.855 – 1.2 0.889 148 1501 exclusion phecode
189.2 Cancer of bladder Neoplasms 1.04 0.974 – 1.1 0.261 1203 9657 exclusion phecode
189.21 Malignant neoplasm of bladder Neoplasms 1.02 0.962 – 1.09 0.456 1134 8977 exclusion phecode
189.4 Malignant neoplasm of other urinary organs Neoplasms 1.01 0.917 – 1.11 0.827 459 4193 exclusion phecode
190 Cancer of eye Neoplasms 1.16 0.922 – 1.46 0.206 81 911 exclusion phecode
191
Manlignant and unknown neoplasms of brain and
Manlignant and unknown neoplasms of brain and nervous system
 Neoplasms 0.95 0.875 – 1.03 0.212 662 7278 exclusion phecode
191.1 Cancer of brain and nervous system Neoplasms 0.945 0.854 – 1.04 0.266 425 4791 exclusion phecode
191.11 Cancer of brain Neoplasms 0.974 0.872 – 1.09 0.643 354 4123 exclusion phecode
193 Thyroid cancer Neoplasms 1.04 0.955 – 1.12 0.395 633 6370 exclusion phecode
194 Cancer of other endocrine glands Neoplasms 1.05 0.945 – 1.17 0.347 353 3804 exclusion phecode
195 Cancer, suspected or other Neoplasms 0.998 0.973 – 1.02 0.892 11042 18386 exclusion phecode
195.1 Malignant neoplasm, other Neoplasms 0.996 0.97 – 1.02 0.748 10829 18375 exclusion phecode
195.3 Malignant neoplasm of head, face, and neck Neoplasms 1.01 0.939 – 1.09 0.752 784 6277 exclusion phecode
196 Radiotherapy Neoplasms 0.936 0.886 – 0.989 0.0193 1500 11121 exclusion phecode
197 Chemotherapy Neoplasms 0.966 0.928 – 1.01 0.0942 3075 16292 exclusion phecode
198 Secondary malignant neoplasm Neoplasms 0.997 0.962 – 1.03 0.89 4014 16097 exclusion phecode
198.1 Secondary malignancy of lymph nodes Neoplasms 1.01 0.965 – 1.05 0.752 2623 14563 exclusion phecode
198.2 Secondary malignancy of respiratory organs Neoplasms 0.96 0.886 – 1.04 0.327 672 6754 exclusion phecode
198.3
Secondary malignant neoplasm of digestive
Secondary malignant neoplasm of digestive systems
 Neoplasms 0.941 0.862 – 1.03 0.172 569 5613 exclusion phecode
198.4 Secondary malignant neoplasm of liver Neoplasms 0.961 0.874 – 1.06 0.414 490 4917 exclusion phecode
198.5 Secondary malignancy of brain/spine Neoplasms 0.967 0.873 – 1.07 0.521 415 4157 exclusion phecode
198.6 Secondary malignancy of bone Neoplasms 0.986 0.901 – 1.08 0.761 526 5422 exclusion phecode
198.7 Secondary malignant neoplasm of skin Neoplasms 0.911 0.789 – 1.05 0.207 217 2137 exclusion phecode
199 Neoplasm of uncertain behavior Neoplasms 0.991 0.954 – 1.03 0.661 3392 17866 exclusion phecode
199.4 Neurofibromatosis Neoplasms 0.881 0.675 – 1.15 0.352 59 637 exclusion phecode
200 Myeloproliferative disease Neoplasms 0.939 0.859 – 1.03 0.168 523 7336 exclusion phecode
200.1 Polycythemia vera Neoplasms 0.839 0.676 – 1.04 0.113 87 1467 exclusion phecode
201 Hodgkin's disease Neoplasms 1.01 0.83 – 1.22 0.954 108 1146 exclusion phecode
202 Cancer of other lymphoid, histiocytic tissue Neoplasms 0.929 0.869 – 0.992 0.0288 965 10205 exclusion phecode
202.2 Non-Hodgkins lymphoma Neoplasms 0.879 0.818 – 0.945 0.000452 818 8740 exclusion phecode
202.21 Nodular lymphoma Neoplasms 0.854 0.775 – 0.942 0.00163 431 4537 exclusion phecode
202.22 Reticulosarcoma Neoplasms 0.945 0.771 – 1.16 0.588 95 1144 exclusion phecode
202.24 Large cell lymphoma Neoplasms 0.884 0.715 – 1.09 0.254 90 1056 exclusion phecode
204 Leukemia Neoplasms 0.923 0.829 – 1.03 0.14 373 4509 exclusion phecode
204.1 Lymphoid leukemia Neoplasms 0.793 0.67 – 0.939 0.00728 143 1565 exclusion phecode
204.11 Lymphoid leukemia, acute Neoplasms 0.625 0.443 – 0.881 0.00722 37 523 exclusion phecode
204.12 Lymphoid leukemia, chronic Neoplasms 0.804 0.666 – 0.969 0.0222 113 1103 exclusion phecode
204.2 Myeloid leukemia Neoplasms 0.84 0.697 – 1.01 0.0668 120 1708 exclusion phecode
204.21 Myeloid leukemia, acute Neoplasms 0.886 0.691 – 1.14 0.341 70 994 exclusion phecode
204.22 Myeloid leukemia, chronic Neoplasms 0.753 0.513 – 1.11 0.148 28 405 exclusion phecode
204.4 Multiple myeloma Neoplasms 0.997 0.821 – 1.21 0.976 113 1367 exclusion phecode
208 Benign neoplasm of colon Neoplasms 0.993 0.962 – 1.02 0.658 4999 25423 exclusion phecode
209 Neuroendocrine tumors Neoplasms 1.09 0.934 – 1.28 0.27 166 1665 exclusion phecode
210 Benign neoplasm of lip, oral cavity, and pharynx Neoplasms 0.99 0.933 – 1.05 0.731 1241 12599 exclusion phecode
211
Benign neoplasm of other parts of digestive
Benign neoplasm of other parts of digestive system
 Neoplasms 1.03 0.998 – 1.07 0.0673 3527 26185 exclusion phecode
212
Benign neoplasm of respiratory and
Benign neoplasm of respiratory and intrathoracic organs
 Neoplasms 1.02 0.963 – 1.09 0.445 1156 12257 exclusion phecode
213 Benign neoplasm of bone and articular cartilage Neoplasms 0.966 0.907 – 1.03 0.288 1050 11466 exclusion phecode
214 Lipoma Neoplasms 1.01 0.935 – 1.09 0.847 748 9352 exclusion phecode
214.1 Lipoma of skin and subcutaneous tissue Neoplasms 1.02 0.925 – 1.12 0.73 474 5752 exclusion phecode
215
Other benign neoplasm of connective and other
Other benign neoplasm of connective and other soft tissue
 Neoplasms 1.01 0.975 – 1.06 0.479 2781 26895 exclusion phecode
216 Benign neoplasm of skin Neoplasms 0.935 0.909 – 0.961 1.74e-06 6580 24853 exclusion phecode
216.1 Screening for malignant neoplasms of the skin Neoplasms 0.844 0.681 – 1.05 0.123 89 1170 exclusion phecode
217 Vascular hamartomas and non-neoplastic nevi Neoplasms 0.899 0.841 – 0.962 0.00192 954 11743 exclusion phecode
217.1 Nevus, non-neoplastic Neoplasms 0.886 0.826 – 0.95 0.000665 880 10986 exclusion phecode
218 Benign neoplasm of uterus Neoplasms 0.97 0.928 – 1.01 0.163 2536 12109 exclusion phecode
218.1 Uterine leiomyoma Neoplasms 0.983 0.923 – 1.05 0.608 1072 11336 exclusion phecode
218.2 Other benign neoplasm of uterus Neoplasms 0.96 0.914 – 1.01 0.0936 1993 11948 exclusion phecode
220 Benign neoplasm of ovary Neoplasms 0.906 0.832 – 0.986 0.0229 581 6397 exclusion phecode
221 Benign neoplasm of other female genital organs Neoplasms 0.993 0.938 – 1.05 0.81 1355 10443 exclusion phecode
222 Benign neoplasm of male genital organs Neoplasms 0.975 0.901 – 1.05 0.528 704 6703 exclusion phecode
223
Benign neoplasm of kidney and other urinary
Benign neoplasm of kidney and other urinary organs
 Neoplasms 1.01 0.952 – 1.08 0.701 1236 9042 exclusion phecode
224 Benign neoplasm of eye Neoplasms 0.95 0.851 – 1.06 0.363 341 4389 exclusion phecode
224.1 Benign neoplasm of eye, uveal Neoplasms 0.961 0.852 – 1.08 0.52 280 3707 exclusion phecode
225
Benign neoplasm of brain and other parts of
Benign neoplasm of brain and other parts of nervous system
 Neoplasms 1 0.926 – 1.08 0.995 724 8148 exclusion phecode
225.1
Benign neoplasm of brain, cranial nerves
Benign neoplasm of brain, cranial nerves, meninges
 Neoplasms 1.01 0.927 – 1.1 0.824 584 6334 exclusion phecode
225.2 Benign neoplasm of spinal cord, meninges Neoplasms 0.951 0.81 – 1.12 0.544 159 2002 exclusion phecode
226 Benign neoplasm of thyroid glands Neoplasms 0.95 0.884 – 1.02 0.169 814 8843 exclusion phecode
227
Benign neoplasm of other endocrine glands and
Benign neoplasm of other endocrine glands and related structures
 Neoplasms 0.942 0.884 – 1 0.0664 1060 11306 exclusion phecode
227.1 Benign neoplasm of adrenal gland Neoplasms 0.999 0.876 – 1.14 0.993 242 3033 exclusion phecode
227.2 Benign neoplasm of parathyroid gland Neoplasms 0.903 0.825 – 0.988 0.0265 531 5350 exclusion phecode
227.3
Benign neoplasm of pituitary gland and
Benign neoplasm of pituitary gland and craniopharyngeal duct (pouch)
 Neoplasms 0.998 0.883 – 1.13 0.979 281 2878 exclusion phecode
228 Hemangioma and lymphangioma, any site Neoplasms 0.935 0.88 – 0.994 0.0315 1135 13638 exclusion phecode
228.1 Hemangioma of skin and subcutaneous tissue Neoplasms 0.944 0.873 – 1.02 0.149 695 8592 exclusion phecode
229 Benign neoplasm of unspecified sites Neoplasms 0.988 0.958 – 1.02 0.415 5341 24567 exclusion phecode
229.1 Benign neoplasm of lymph nodes Neoplasms 0.995 0.962 – 1.03 0.759 4094 22828 exclusion phecode
240 Simple and unspecified goiter Endocrine/metabolic 0.961 0.883 – 1.05 0.365 595 6931 exclusion phecode
241 Nontoxic nodular goiter Endocrine/metabolic 0.974 0.925 – 1.02 0.307 1692 15611 exclusion phecode
241.1 Nontoxic uninodular goiter Endocrine/metabolic 0.981 0.925 – 1.04 0.507 1280 13898 exclusion phecode
241.2 Nontoxic multinodular goiter Endocrine/metabolic 1 0.928 – 1.08 0.973 739 8682 exclusion phecode
242 Thyrotoxicosis with or without goiter Endocrine/metabolic 1.02 0.943 – 1.09 0.68 748 9269 exclusion phecode
242.1 Graves' disease Endocrine/metabolic 0.978 0.867 – 1.1 0.714 306 3544 exclusion phecode
242.2 Toxic multinodular goiter Endocrine/metabolic 1.04 0.81 – 1.35 0.741 61 839 exclusion phecode
242.3 Exophthalmos Endocrine/metabolic 0.92 0.79 – 1.07 0.287 180 2034 exclusion phecode
242.31 Thyrotoxic exophthalmos Endocrine/metabolic 0.953 0.774 – 1.17 0.652 97 1037 exclusion phecode
244 Hypothyroidism Endocrine/metabolic 0.997 0.965 – 1.03 0.865 4683 22694 exclusion phecode
244.1 Secondary hypothyroidism Endocrine/metabolic 0.986 0.926 – 1.05 0.669 1087 12044 exclusion phecode
244.2 Acquired hypothyroidism Endocrine/metabolic 0.98 0.904 – 1.06 0.623 660 8318 exclusion phecode
244.4 Hypothyroidism NOS Endocrine/metabolic 0.994 0.961 – 1.03 0.737 4294 22330 exclusion phecode
245 Thyroiditis Endocrine/metabolic 0.928 0.844 – 1.02 0.123 481 5569 exclusion phecode
245.2 Chronic thyroiditis Endocrine/metabolic 0.908 0.818 – 1.01 0.0723 406 4636 exclusion phecode
245.21 Chronic lymphocytic thyroiditis Endocrine/metabolic 0.901 0.811 – 1 0.0523 402 4589 exclusion phecode
246 Other disorders of thyroid Endocrine/metabolic 0.998 0.962 – 1.04 0.936 3558 20993 exclusion phecode
246.2 Thyroid cyst Endocrine/metabolic 1.03 0.771 – 1.37 0.846 56 685 exclusion phecode
246.7 Abnormal results of function study of thyroid Endocrine/metabolic 0.963 0.872 – 1.06 0.457 427 5949 exclusion phecode
249 Secondary diabetes mellitus Endocrine/metabolic 1.11 0.992 – 1.23 0.0695 449 6091 exclusion phecode
250 Diabetes mellitus Endocrine/metabolic 1.05 1.02 – 1.08 0.000577 6846 23921 exclusion phecode
250.1 Type 1 diabetes Endocrine/metabolic 1.09 0.997 – 1.19 0.059 1180 8631 exclusion phecode
250.11 Type 1 diabetes with ketoacidosis Endocrine/metabolic 1.37 1.07 – 1.75 0.0124 161 701 exclusion phecode
250.12 Type 1 diabetes with renal manifestations Endocrine/metabolic 1.13 0.951 – 1.34 0.165 268 1965 exclusion phecode
250.13 Type 1 diabetes with ophthalmic manifestations Endocrine/metabolic 1.05 0.893 – 1.22 0.578 417 2218 exclusion phecode
250.14 Type 1 diabetes with neurological manifestations Endocrine/metabolic 1.14 0.961 – 1.36 0.133 297 1953 exclusion phecode
250.15
Diabetes type 1 with peripheral circulatory
Diabetes type 1 with peripheral circulatory disorders
 Endocrine/metabolic 1.24 0.894 – 1.71 0.2 57 598 exclusion phecode
250.2 Type 2 diabetes Endocrine/metabolic 1.09 1.06 – 1.13 4.63e-07 4852 22097 exclusion phecode
250.21 Type 2 diabetes with ketoacidosis Endocrine/metabolic 1.23 0.967 – 1.55 0.0922 136 964 exclusion phecode
250.22 Type 2 diabetes with renal manifestations Endocrine/metabolic 1.1 1 – 1.2 0.039 673 9775 exclusion phecode
250.23 Type 2 diabetes with ophthalmic manifestations Endocrine/metabolic 1.05 0.954 – 1.16 0.302 687 7009 exclusion phecode
250.24 Type 2 diabetes with neurological manifestations Endocrine/metabolic 1.13 1.04 – 1.23 0.00265 876 11960 exclusion phecode
250.25
Diabetes type 2 with peripheral circulatory
Diabetes type 2 with peripheral circulatory disorders
 Endocrine/metabolic 1.17 1.01 – 1.35 0.0333 241 4465 exclusion phecode
250.3 Insulin pump user Endocrine/metabolic 1.05 0.98 – 1.12 0.177 1582 15216 exclusion phecode
250.4 Abnormal glucose Endocrine/metabolic 0.995 0.957 – 1.04 0.813 3714 22915 exclusion phecode
250.41 Impaired fasting glucose Endocrine/metabolic 0.947 0.875 – 1.03 0.179 726 11589 exclusion phecode
250.42 Other abnormal glucose Endocrine/metabolic 0.999 0.958 – 1.04 0.957 3349 22424 exclusion phecode
250.5 Glycosuria or Acetonuria Endocrine/metabolic 1.17 0.878 – 1.55 0.288 56 804 exclusion phecode
250.6 Polyneuropathy in diabetes Endocrine/metabolic 1.14 1.04 – 1.24 0.00598 752 9699 exclusion phecode
250.7 Diabetic retinopathy Endocrine/metabolic 1 0.924 – 1.09 0.937 751 7107 exclusion phecode
251 Other disorders of pancreatic internal secretion Endocrine/metabolic 1.05 0.95 – 1.15 0.354 446 5773 exclusion phecode
251.1 Hypoglycemia Endocrine/metabolic 1.1 0.995 – 1.22 0.0632 553 6520 exclusion phecode
252 Disorders of parathyroid gland Endocrine/metabolic 0.967 0.913 – 1.03 0.265 1270 15250 exclusion phecode
252.1 Hyperparathyroidism Endocrine/metabolic 0.968 0.911 – 1.03 0.302 1154 13950 exclusion phecode
252.2 Hypoparathyroidism Endocrine/metabolic 0.909 0.808 – 1.02 0.115 303 3537 exclusion phecode
253
Disorders of the pituitary gland and its
Disorders of the pituitary gland and its hypothalamic control
 Endocrine/metabolic 0.96 0.869 – 1.06 0.415 428 5871 exclusion phecode
253.1 Pituitary hyperfunction Endocrine/metabolic 1.01 0.848 – 1.2 0.911 132 1859 exclusion phecode
253.11 Acromegaly and gigantism Endocrine/metabolic 0.977 0.715 – 1.34 0.884 46 586 exclusion phecode
253.2 Pituitary hypofunction Endocrine/metabolic 1.12 0.926 – 1.35 0.245 121 1544 exclusion phecode
253.3 Diabetes insipidus Endocrine/metabolic 0.933 0.702 – 1.24 0.632 49 601 exclusion phecode
253.4 Anterior pituitary disorders Endocrine/metabolic 1.05 0.768 – 1.44 0.754 43 779 exclusion phecode
253.7 Other disorders of neurohypophysis Endocrine/metabolic 0.878 0.661 – 1.17 0.37 47 713 exclusion phecode
255 Disorders of adrenal glands Endocrine/metabolic 1.01 0.939 – 1.09 0.74 737 10260 exclusion phecode
255.1 Adrenal hyperfunction Endocrine/metabolic 0.99 0.852 – 1.15 0.89 181 2624 exclusion phecode
255.11 Cushing's syndrome Endocrine/metabolic 0.925 0.753 – 1.14 0.459 93 1299 exclusion phecode
255.12 Hyperaldosteronism Endocrine/metabolic 0.969 0.741 – 1.27 0.82 57 923 exclusion phecode
255.2 Adrenal hypofunction Endocrine/metabolic 1 0.885 – 1.14 0.956 270 4262 exclusion phecode
255.21 Glucocorticoid deficiency Endocrine/metabolic 1 0.882 – 1.14 0.982 254 4082 exclusion phecode
256 Ovarian dysfunction Endocrine/metabolic 0.891 0.822 – 0.966 0.00527 648 7944 exclusion phecode
256.4 Polycystic ovaries Endocrine/metabolic 0.988 0.893 – 1.09 0.817 405 5551 exclusion phecode
257 Testicular dysfunction Endocrine/metabolic 1.04 0.932 – 1.16 0.495 358 6115 exclusion phecode
257.1 Testicular hypofunction Endocrine/metabolic 1.04 0.93 – 1.16 0.507 340 5897 exclusion phecode
258 Iatrogenic endocrine disorders Endocrine/metabolic 1.27 0.965 – 1.68 0.0879 55 603 exclusion phecode
258.1 Postablative ovarian failure Endocrine/metabolic 0.758 0.577 – 0.996 0.0464 53 808 exclusion phecode
259 Other endocrine disorders Endocrine/metabolic 0.985 0.898 – 1.08 0.749 489 7100 exclusion phecode
260 Protein-calorie malnutrition Endocrine/metabolic 1.05 1 – 1.11 0.05 1565 19137 exclusion phecode
260.1 Cachexia Endocrine/metabolic 1.01 0.857 – 1.18 0.946 163 2057 exclusion phecode
260.2 severe protein-calorie malnutrition Endocrine/metabolic 1.04 0.975 – 1.12 0.224 922 11956 exclusion phecode
260.22 Nutritional marasmus Endocrine/metabolic 1.04 0.924 – 1.16 0.532 314 4399 exclusion phecode
260.3 Adult failure to thrive Endocrine/metabolic 1.14 1.02 – 1.28 0.0235 313 4410 exclusion phecode
260.6 Anorexia Endocrine/metabolic 1.06 0.961 – 1.18 0.235 398 6171 exclusion phecode
260.7 Polyphagia Endocrine/metabolic 1.17 0.796 – 1.71 0.43 23 467 exclusion phecode
261 Vitamin deficiency Endocrine/metabolic 0.955 0.921 – 0.99 0.0125 3498 25812 exclusion phecode
261.1 Vitamin A deficiency Endocrine/metabolic 0.803 0.552 – 1.17 0.251 27 519 exclusion phecode
261.2 Vitamin B-complex deficiencies Endocrine/metabolic 0.948 0.85 – 1.06 0.332 348 6042 exclusion phecode
261.4 Vitamin D deficiency Endocrine/metabolic 0.961 0.925 – 0.997 0.0357 3265 25841 exclusion phecode
261.41 Rickets or osteomalacia Endocrine/metabolic 0.787 0.52 – 1.19 0.256 21 369 exclusion phecode
262 Mineral deficiency NEC Endocrine/metabolic 0.988 0.899 – 1.09 0.808 458 8548 exclusion phecode
263 Other nutritional deficiency Endocrine/metabolic 0.935 0.868 – 1.01 0.0766 746 11485 exclusion phecode
264 Lack of normal physiological development Endocrine/metabolic 1.03 0.86 – 1.22 0.779 131 1791 exclusion phecode
264.2 Failure to thrive (childhood) Endocrine/metabolic 1.11 0.827 – 1.49 0.487 52 902 exclusion phecode
264.9
Lack of normal physiological development
Lack of normal physiological development, unspecified
 Endocrine/metabolic 0.939 0.72 – 1.22 0.641 56 628 exclusion phecode
269 Proteinuria Endocrine/metabolic 0.989 0.916 – 1.07 0.79 702 9342 exclusion phecode
270
Disorders of protein plasma/amino-acid
Disorders of protein plasma/amino-acid transport and metabolism
 Endocrine/metabolic 0.966 0.876 – 1.07 0.497 428 6385 exclusion phecode
270.1 Disturbances of amino-acid transport Endocrine/metabolic 1.04 0.828 – 1.3 0.757 85 1187 exclusion phecode
270.11
Disturbances of sulphur-bearing amino-acid
Disturbances of sulphur-bearing amino-acid metabolism
 Endocrine/metabolic 0.999 0.778 – 1.28 0.995 68 948 exclusion phecode
270.2 Disorders of amino-acid metabolism Endocrine/metabolic 0.995 0.709 – 1.4 0.979 31 628 exclusion phecode
270.3 Disorders of plasma protein metabolism Endocrine/metabolic 0.964 0.862 – 1.08 0.525 322 4814 exclusion phecode
270.32 Paraproteinemia Endocrine/metabolic 0.978 0.835 – 1.15 0.784 165 2458 exclusion phecode
270.33 Amyloidosis Endocrine/metabolic 1.1 0.806 – 1.49 0.558 39 472 exclusion phecode
270.34 Alpha-1-antitrypsin deficiency Endocrine/metabolic 1.01 0.686 – 1.48 0.976 28 461 exclusion phecode
270.38
Other specified disorders of plasma protein
Other specified disorders of plasma protein metabolism
 Endocrine/metabolic 0.901 0.757 – 1.07 0.24 131 2005 exclusion phecode
271
Disorders of carbohydrate transport and
Disorders of carbohydrate transport and metabolism
 Endocrine/metabolic 0.946 0.892 – 1 0.0652 1221 18790 exclusion phecode
271.3
Intestinal disaccharidase deficiencies and
Intestinal disaccharidase deficiencies and disaccharide malabsorption
 Endocrine/metabolic 0.949 0.894 – 1.01 0.086 1188 18272 exclusion phecode
271.9
Other disorders of carbohydrate transport and
Other disorders of carbohydrate transport and metabolism
 Endocrine/metabolic 0.693 0.509 – 0.943 0.0196 41 678 exclusion phecode
272 Disorders of lipoid metabolism Endocrine/metabolic 1.02 0.992 – 1.05 0.167 10060 20488 exclusion phecode
272.1 Hyperlipidemia Endocrine/metabolic 1.02 0.993 – 1.05 0.143 10043 20476 exclusion phecode
272.11 Hypercholesterolemia Endocrine/metabolic 1 0.962 – 1.05 0.9 2930 16233 exclusion phecode
272.12 Hyperglyceridemia Endocrine/metabolic 0.944 0.86 – 1.04 0.226 476 8849 exclusion phecode
272.13 Mixed hyperlipidemia Endocrine/metabolic 0.979 0.924 – 1.04 0.469 1472 13790 exclusion phecode
272.9 Unspecified disorder of lipoid metabolism Endocrine/metabolic 0.883 0.745 – 1.05 0.155 138 2216 exclusion phecode
274 Gout and other crystal arthropathies Endocrine/metabolic 1.06 1 – 1.13 0.0452 1222 14679 exclusion phecode
274.1 Gout Endocrine/metabolic 1.06 1 – 1.13 0.0452 1161 14190 exclusion phecode
274.11 Gouty arthropathy Endocrine/metabolic 0.968 0.88 – 1.07 0.511 458 6722 exclusion phecode
274.2 Crystal arthropathies Endocrine/metabolic 1.03 0.839 – 1.27 0.762 90 1251 exclusion phecode
274.21 Chondrocalcinosis Endocrine/metabolic 1.02 0.824 – 1.26 0.855 85 1170 exclusion phecode
275 Disorders of mineral metabolism Endocrine/metabolic 1.02 0.973 – 1.06 0.461 2196 25197 exclusion phecode
275.1 Disorders of iron metabolism Hematopoietic 1.04 0.833 – 1.29 0.753 82 1439 exclusion phecode
275.11 Hereditary hemochromatosis Hematopoietic 1.06 0.791 – 1.43 0.679 48 646 exclusion phecode
275.2 Disorders of copper metabolism Endocrine/metabolic 1.29 0.869 – 1.92 0.206 26 410 exclusion phecode
275.3 Disorders of magnesium metabolism Endocrine/metabolic 0.949 0.868 – 1.04 0.246 532 7661 exclusion phecode
275.5 Disorders of calcium/phosphorus metabolism Endocrine/metabolic 1.01 0.961 – 1.06 0.681 1728 21390 exclusion phecode
275.51 Hypocalcemia Endocrine/metabolic 1 0.911 – 1.1 0.991 490 6124 exclusion phecode
275.53 Disorders of phosphorus metabolism Endocrine/metabolic 1.03 0.948 – 1.11 0.514 664 9157 exclusion phecode
275.6 Hypercalcemia Endocrine/metabolic 0.978 0.904 – 1.06 0.575 701 9403 exclusion phecode
276
Disorders of fluid, electrolyte, and acid-base
Disorders of fluid, electrolyte, and acid-base balance
 Endocrine/metabolic 1.01 0.977 – 1.04 0.58 4568 26723 exclusion phecode
276.1 Electrolyte imbalance Endocrine/metabolic 1 0.962 – 1.04 0.977 2986 24426 exclusion phecode
276.11 Hyperosmolality and/or hypernatremia Endocrine/metabolic 0.99 0.859 – 1.14 0.888 202 3759 exclusion phecode
276.12 Hyposmolality and/or hyponatremia Endocrine/metabolic 0.989 0.932 – 1.05 0.713 1195 16110 exclusion phecode
276.13 Hyperpotassemia Endocrine/metabolic 1.04 0.987 – 1.11 0.129 1322 17484 exclusion phecode
276.14 Hypopotassemia Endocrine/metabolic 0.993 0.928 – 1.06 0.843 895 14759 exclusion phecode
276.4 Acid-base balance disorder Endocrine/metabolic 1.06 0.989 – 1.13 0.1 879 14174 exclusion phecode
276.41 Acidosis Endocrine/metabolic 1.07 0.997 – 1.16 0.0584 753 12246 exclusion phecode
276.42 Alkalosis Endocrine/metabolic 0.945 0.818 – 1.09 0.441 189 3293 exclusion phecode
276.5 Hypovolemia Endocrine/metabolic 1.02 0.978 – 1.07 0.326 2213 24713 exclusion phecode
276.6 Fluid overload Endocrine/metabolic 1.03 0.936 – 1.12 0.585 495 9146 exclusion phecode
276.8 Polydipsia Endocrine/metabolic 1.37 1.03 – 1.83 0.0297 48 875 exclusion phecode
277 Other disorders of metabolism Endocrine/metabolic 0.952 0.907 – 1 0.0497 1781 24413 exclusion phecode
277.2
Other disorders of purine and pyrimidine
Other disorders of purine and pyrimidine metabolism
 Endocrine/metabolic 0.965 0.812 – 1.15 0.69 133 2623 exclusion phecode
277.4 Disorders of bilirubin excretion Endocrine/metabolic 1.01 0.909 – 1.12 0.836 374 4862 exclusion phecode
277.5 Other disorders of lipoid metabolism Endocrine/metabolic 0.922 0.832 – 1.02 0.118 397 6232 exclusion phecode
277.51 Lipoprotein disorders Endocrine/metabolic 0.971 0.866 – 1.09 0.607 319 5148 exclusion phecode
277.7 Dysmetabolic syndrome X Endocrine/metabolic 0.918 0.802 – 1.05 0.216 219 5627 exclusion phecode
278 Overweight, obesity and other hyperalimentation Endocrine/metabolic 1.06 1.03 – 1.08 7.21e-06 10021 21607 exclusion phecode
278.1 Obesity Endocrine/metabolic 1.07 1.04 – 1.09 5.54e-07 8626 21598 exclusion phecode
278.11 Morbid obesity Endocrine/metabolic 1.09 1.05 – 1.13 3.66e-06 3414 21481 exclusion phecode
278.3 Localized adiposity Endocrine/metabolic 1.12 0.936 – 1.34 0.215 128 2525 exclusion phecode
278.4 Abnormal weight gain Endocrine/metabolic 0.957 0.89 – 1.03 0.244 778 13854 exclusion phecode
279 Disorders involving the immune mechanism Endocrine/metabolic 0.982 0.93 – 1.04 0.502 1439 20077 exclusion phecode
279.1 Immunity deficiency Endocrine/metabolic 0.997 0.911 – 1.09 0.943 517 8009 exclusion phecode
279.11 Deficiency of humoral immunity Endocrine/metabolic 0.933 0.789 – 1.1 0.419 140 2255 exclusion phecode
279.2 Autoimmune disease NEC Endocrine/metabolic 1 0.894 – 1.12 1 330 5287 exclusion phecode
279.7 Other immunological findings Endocrine/metabolic 1 0.958 – 1.05 0.966 2203 25699 exclusion phecode
279.8
Other specified disorders involving the immune
Other specified disorders involving the immune mechanism
 Endocrine/metabolic 1.01 0.892 – 1.14 0.92 274 4225 exclusion phecode
280 Iron deficiency anemias Hematopoietic 0.978 0.934 – 1.02 0.344 2055 22330 exclusion phecode
280.1
Iron deficiency anemias, unspecified or not due
Iron deficiency anemias, unspecified or not due to blood loss
 Hematopoietic 0.98 0.935 – 1.03 0.385 1981 22172 exclusion phecode
280.2
Iron deficiency anemia secondary to blood loss
Iron deficiency anemia secondary to blood loss (chronic)
 Hematopoietic 0.937 0.87 – 1.01 0.0802 781 12406 exclusion phecode
281 Other deficiency anemia Hematopoietic 0.963 0.836 – 1.11 0.607 206 3622 exclusion phecode
281.1 Megaloblastic anemia Hematopoietic 1.01 0.83 – 1.22 0.934 111 1767 exclusion phecode
281.11 Pernicious anemia Hematopoietic 1.14 0.846 – 1.53 0.398 47 772 exclusion phecode
281.12 Other vitamin B12 deficiency anemia Hematopoietic 1.08 0.874 – 1.34 0.467 90 1275 exclusion phecode
281.9 Deficiency anemias Hematopoietic 0.885 0.724 – 1.08 0.236 103 2013 exclusion phecode
282 Hereditary hemolytic anemias Hematopoietic 1.09 0.929 – 1.29 0.282 153 2270 exclusion phecode
282.8 Other hemoglobinopathies Hematopoietic 1.08 0.879 – 1.32 0.473 100 1473 exclusion phecode
282.9 Other hereditary hemolytic anemias Hematopoietic 1.09 0.862 – 1.37 0.476 83 1376 exclusion phecode
283 Acquired hemolytic anemias Hematopoietic 1.08 0.862 – 1.34 0.522 86 1100 exclusion phecode
283.1 Autoimmune hemolytic anemias Hematopoietic 1.32 0.95 – 1.84 0.0974 38 445 exclusion phecode
284 Aplastic anemia Hematopoietic 0.948 0.848 – 1.06 0.343 337 4933 exclusion phecode
284.1 Pancytopenia Hematopoietic 0.943 0.838 – 1.06 0.326 301 4325 exclusion phecode
285 Other anemias Hematopoietic 1.03 0.998 – 1.06 0.0667 6336 24493 exclusion phecode
285.1 Acute posthemorrhagic anemia Hematopoietic 1.03 0.98 – 1.08 0.255 1802 19804 exclusion phecode
285.2 Anemia of chronic disease Hematopoietic 1.03 0.966 – 1.1 0.353 943 14113 exclusion phecode
285.21 Anemia in chronic kidney disease Hematopoietic 1.06 0.959 – 1.18 0.238 380 6349 exclusion phecode
285.22 Anemia in neoplastic disease Hematopoietic 0.971 0.871 – 1.08 0.592 363 4907 exclusion phecode
286 Coagulation defects Hematopoietic 1.02 0.97 – 1.07 0.463 1820 23321 exclusion phecode
286.1 Congenital coagulation defects Hematopoietic 1.01 0.847 – 1.19 0.944 137 1741 exclusion phecode
286.11 Von willebrand's disease Hematopoietic 1.07 0.811 – 1.41 0.629 54 586 exclusion phecode
286.12
Congenital deficiency of other clotting factors
Congenital deficiency of other clotting factors (including factor VII)
 Hematopoietic 1.02 0.804 – 1.3 0.847 62 890 exclusion phecode
286.2
Encounter for long-term (current) use of
Encounter for long-term (current) use of anticoagulants
 Hematopoietic 0.973 0.923 – 1.03 0.323 1507 17805 exclusion phecode
286.3
Coagulation defects complicating pregnancy or
Coagulation defects complicating pregnancy or postpartum
 Hematopoietic 0.955 0.741 – 1.23 0.72 68 783 exclusion phecode
286.4 Acquired coagulation factor deficiency Hematopoietic 1.05 0.863 – 1.29 0.607 108 1727 exclusion phecode
286.5
Hemorrhagic disorder due to intrinsic
Hemorrhagic disorder due to intrinsic circulating anticoagulants
 Hematopoietic 0.988 0.746 – 1.31 0.931 51 867 exclusion phecode
286.6 Defibrination syndrome Hematopoietic 1.01 0.956 – 1.07 0.666 1253 17583 exclusion phecode
286.7 Other and unspecified coagulation defects Hematopoietic 1.01 0.956 – 1.07 0.74 1431 20377 exclusion phecode
286.8 Hypercoagulable state Hematopoietic 0.941 0.853 – 1.04 0.223 440 5920 exclusion phecode
286.81 Primary hypercoagulable state Hematopoietic 0.932 0.843 – 1.03 0.167 421 5671 exclusion phecode
286.9 Abnormal coagulation profile Hematopoietic 1.11 1.01 – 1.22 0.0311 469 7846 exclusion phecode
287 Purpura and other hemorrhagic conditions Hematopoietic 0.961 0.913 – 1.01 0.131 1622 19750 exclusion phecode
287.1 Spontaneous ecchymoses Hematopoietic 1.04 0.84 – 1.3 0.703 87 1440 exclusion phecode
287.3 Thrombocytopenia Hematopoietic 0.963 0.912 – 1.02 0.171 1450 18240 exclusion phecode
287.31 Primary thrombocytopenia Hematopoietic 1.06 0.946 – 1.2 0.3 303 4165 exclusion phecode
287.32 Secondary thrombocytopenia Hematopoietic 0.909 0.803 – 1.03 0.13 283 3960 exclusion phecode
287.4 Qualitative platelet defects Hematopoietic 0.947 0.724 – 1.24 0.693 57 803 exclusion phecode
288 Diseases of white blood cells Hematopoietic 1.02 0.976 – 1.06 0.413 2376 25939 exclusion phecode
288.1 Decreased white blood cell count Hematopoietic 0.973 0.906 – 1.04 0.444 836 11131 exclusion phecode
288.11 Neutropenia Hematopoietic 0.969 0.889 – 1.06 0.465 582 7642 exclusion phecode
288.2 Elevated white blood cell count Hematopoietic 1.02 0.97 – 1.07 0.5 1909 24732 exclusion phecode
288.3 Eosinophilia Hematopoietic 0.935 0.751 – 1.16 0.544 88 1302 exclusion phecode
289 Other diseases of blood and blood-forming organs Hematopoietic 0.983 0.916 – 1.06 0.634 827 12164 exclusion phecode
289.3
Personal history of diseases of blood and
Personal history of diseases of blood and blood-forming organs
 Hematopoietic 0.946 0.856 – 1.04 0.27 433 6356 exclusion phecode
289.4 Lymphadenitis Hematopoietic 0.937 0.897 – 0.98 0.00402 2205 24599 exclusion phecode
289.5 Diseases of spleen Hematopoietic 0.888 0.765 – 1.03 0.118 187 2692 exclusion phecode
289.8 Polycythemia, secondary Hematopoietic 0.862 0.699 – 1.06 0.163 91 1687 exclusion phecode
289.9 Abnormality of red blood cells Hematopoietic 1.06 0.909 – 1.24 0.458 173 2634 exclusion phecode
290
Delirium dementia and amnestic and other
Delirium dementia and amnestic and other cognitive disorders
 Mental Disorders 1.01 0.924 – 1.1 0.849 548 8000 exclusion phecode
290.1 Dementias Mental Disorders 0.845 0.733 – 0.974 0.0203 204 3437 exclusion phecode
290.11 Alzheimer's disease Mental Disorders 0.765 0.596 – 0.982 0.0356 65 991 exclusion phecode
290.12 Dementia with cerebral degenerations Mental Disorders 0.691 0.467 – 1.02 0.0651 24 574 exclusion phecode
290.13 Senile dementia Mental Disorders 0.875 0.737 – 1.04 0.127 140 2150 exclusion phecode
290.16 Vascular dementia Mental Disorders 0.964 0.668 – 1.39 0.843 30 547 exclusion phecode
290.2 Delirium due to conditions classified elsewhere Mental Disorders 1.15 1.02 – 1.3 0.0179 302 5063 exclusion phecode
290.3
Other persistent mental disorders due to
Other persistent mental disorders due to conditions classified elsewhere
 Mental Disorders 1.02 0.906 – 1.15 0.753 296 6023 exclusion phecode
291
Other specified nonpsychotic and/or transient
Other specified nonpsychotic and/or transient mental disorders
 Mental Disorders 1.03 0.953 – 1.11 0.488 751 17716 exclusion phecode
291.1
Transient mental disorders due to conditions
Transient mental disorders due to conditions classified elsewhere
 Mental Disorders 0.915 0.746 – 1.12 0.391 98 1357 exclusion phecode
291.4
Specific nonpsychotic mental disorders due to
Specific nonpsychotic mental disorders due to brain damage
 Mental Disorders 1.12 0.958 – 1.31 0.155 163 3444 exclusion phecode
291.8 Alteration of consciousness Mental Disorders 1.04 0.948 – 1.13 0.433 520 14118 exclusion phecode
292 Neurological disorders Mental Disorders 1.02 0.976 – 1.06 0.397 2410 27839 exclusion phecode
292.1 Aphasia/speech disturbance Mental Disorders 0.979 0.915 – 1.05 0.534 924 13996 exclusion phecode
292.11 Aphasia Mental Disorders 0.958 0.847 – 1.08 0.488 277 4610 exclusion phecode
292.12 Symbolic dysfunction Mental Disorders 0.876 0.704 – 1.09 0.232 85 1433 exclusion phecode
292.2 Mild cognitive impairment Mental Disorders 0.959 0.804 – 1.15 0.646 122 2650 exclusion phecode
292.3 Memory loss Mental Disorders 0.955 0.88 – 1.04 0.268 620 12764 exclusion phecode
292.4 Altered mental status Mental Disorders 1.06 0.994 – 1.13 0.0734 967 15911 exclusion phecode
292.5 Transient alteration of awareness Mental Disorders 0.838 0.708 – 0.993 0.0406 135 3038 exclusion phecode
292.6 Hallucinations Mental Disorders 1.03 0.803 – 1.32 0.83 59 1513 exclusion phecode
293 Symptoms involving head and neck Mental Disorders 1.01 0.867 – 1.17 0.946 187 2820 exclusion phecode
293.1
Swelling, mass, or lump in head and neck
Swelling, mass, or lump in head and neck [Space-occupying lesion, intracranial NOS]
 Mental Disorders 0.975 0.936 – 1.02 0.231 2552 26272 exclusion phecode
295 Schizophrenia and other psychotic disorders Mental Disorders 1.09 0.972 – 1.22 0.138 313 6599 exclusion phecode
295.1 Schizophrenia Mental Disorders 1.15 0.892 – 1.48 0.281 66 1087 exclusion phecode
295.2 Paranoid disorders Mental Disorders 1.28 0.935 – 1.75 0.124 38 869 exclusion phecode
295.3 Psychosis Mental Disorders 1.1 0.964 – 1.26 0.156 234 5339 exclusion phecode
296 Mood disorders Mental Disorders 1.09 1.06 – 1.12 5.48e-10 7567 17059 exclusion phecode
296.1 Bipolar Mental Disorders 1.08 0.988 – 1.18 0.0894 565 9472 exclusion phecode
296.2 Depression Mental Disorders 1.1 1.07 – 1.13 8.85e-11 7238 17056 exclusion phecode
296.22 Major depressive disorder Mental Disorders 1.11 1.08 – 1.14 3.92e-12 6689 17055 exclusion phecode
297 Suicidal ideation or attempt Mental Disorders 1.08 0.971 – 1.21 0.155 371 7640 exclusion phecode
297.1 Suicidal ideation Mental Disorders 1.13 0.995 – 1.27 0.0596 277 6175 exclusion phecode
297.2 Suicide or self-inflicted injury Mental Disorders 1.03 0.851 – 1.24 0.773 117 2288 exclusion phecode
300 Anxiety disorders Mental Disorders 1.08 1.05 – 1.11 4.69e-08 7903 17051 exclusion phecode
300.1 Anxiety disorder Mental Disorders 1.08 1.05 – 1.11 3.61e-08 7426 17054 exclusion phecode
300.11 Generalized anxiety disorder Mental Disorders 1.11 1.06 – 1.16 7.83e-06 2351 16745 exclusion phecode
300.12 Agorophobia, social phobia, and panic disorder Mental Disorders 1.08 0.981 – 1.18 0.12 537 9603 exclusion phecode
300.13 Phobia Mental Disorders 1.07 0.969 – 1.18 0.181 444 7892 exclusion phecode
300.3 Obsessive-compulsive disorders Mental Disorders 1.06 0.897 – 1.26 0.479 146 2560 exclusion phecode
300.4 Dysthymic disorder Mental Disorders 1.1 1.03 – 1.18 0.00601 871 13638 exclusion phecode
300.8 Acute reaction to stress Mental Disorders 1.14 0.979 – 1.34 0.0913 164 4004 exclusion phecode
300.9 Posttraumatic stress disorder Mental Disorders 1.19 1.06 – 1.34 0.00423 301 6664 exclusion phecode
301 Personality disorders Mental Disorders 1.14 0.977 – 1.33 0.0951 171 3921 exclusion phecode
301.2 Antisocial/borderline personality disorder Mental Disorders 1.22 0.975 – 1.52 0.0821 79 2092 exclusion phecode
302 Sexual and gender identity disorders Mental Disorders 1.01 0.957 – 1.06 0.792 1925 10915 exclusion phecode
302.1 Decreased libido Mental Disorders 0.946 0.812 – 1.1 0.482 177 3470 exclusion phecode
303 Psychogenic and somatoform disorders Mental Disorders 0.973 0.937 – 1.01 0.164 3409 16286 exclusion phecode
303.1 Dissociative disorder Mental Disorders 1.16 0.866 – 1.56 0.314 41 1341 exclusion phecode
303.3 Psychogenic disorder Mental Disorders 0.969 0.933 – 1.01 0.116 3277 16145 exclusion phecode
303.31
Gastrointestinal malfunction arising from
Gastrointestinal malfunction arising from mental factors
 Mental Disorders 1 0.866 – 1.15 0.995 199 3797 exclusion phecode
303.4 Somatoform disorder Mental Disorders 0.985 0.899 – 1.08 0.738 493 9373 exclusion phecode
304 Adjustment reaction Mental Disorders 1 0.949 – 1.05 0.998 1629 16704 exclusion phecode
305.2 Eating disorder Mental Disorders 1.05 0.939 – 1.18 0.372 295 7055 exclusion phecode
306 Other mental disorder Mental Disorders 1.02 0.948 – 1.1 0.572 746 11754 exclusion phecode
306.1 Mental disorders durring/after pregnancy Mental Disorders 1.03 0.915 – 1.15 0.665 348 3198 exclusion phecode
306.9 Tension headache Mental Disorders 1.01 0.896 – 1.15 0.823 266 6138 exclusion phecode
312 Conduct disorders Mental Disorders 1.23 1 – 1.49 0.0451 96 1803 exclusion phecode
312.3 Impulse control disorder Mental Disorders 1.47 1.06 – 2.05 0.0225 34 542 exclusion phecode
313 Pervasive developmental disorders Mental Disorders 1.08 1.01 – 1.17 0.0255 822 10852 exclusion phecode
313.1 Attention deficit hyperactivity disorder Mental Disorders 1.09 1.01 – 1.18 0.023 739 9873 exclusion phecode
313.2 Tics and stuttering Mental Disorders 1.09 0.768 – 1.56 0.62 32 560 exclusion phecode
313.3 Autism Mental Disorders 1 0.742 – 1.36 0.98 40 492 exclusion phecode
315 Develomental delays and disorders Mental Disorders 0.993 0.874 – 1.13 0.908 252 4662 exclusion phecode
315.1 Learning disorder Mental Disorders 1.16 0.845 – 1.59 0.361 38 657 exclusion phecode
315.2 Speech and language disorder Mental Disorders 0.884 0.724 – 1.08 0.227 99 1768 exclusion phecode
316 Substance addiction and disorders Mental Disorders 1.11 1.05 – 1.16 5.94e-05 1739 23274 exclusion phecode
316.1 Polyneuropathy due to drugs Mental Disorders 0.956 0.858 – 1.07 0.419 354 4313 exclusion phecode
317 Alcohol-related disorders Mental Disorders 1.1 1.04 – 1.16 0.00114 1338 16116 exclusion phecode
317.1 Alcoholism Mental Disorders 1.1 1.04 – 1.18 0.00232 1038 13495 exclusion phecode
317.11 Alcoholic liver damage Mental Disorders 1.08 0.929 – 1.24 0.332 197 2694 exclusion phecode
318 Tobacco use disorder Mental Disorders 1.14 1.1 – 1.17 8.99e-16 4935 24835 exclusion phecode
320 Meningitis Neurological 0.969 0.84 – 1.12 0.667 195 2627 exclusion phecode
323 Encephalitis Neurological 1.1 0.872 – 1.4 0.414 73 1215 exclusion phecode
323.8 Encephalitis, non-infectious Neurological 1.08 0.832 – 1.4 0.56 59 1032 exclusion phecode
324 Other CNS infection and poliomyelitis Neurological 1 0.846 – 1.19 0.981 143 1895 exclusion phecode
325
Phlebitis and thrombophlebitis of intracranial
Phlebitis and thrombophlebitis of intracranial venous sinuses
 Neurological 1.08 0.736 – 1.57 0.708 27 338 exclusion phecode
327 Sleep disorders Neurological 1.12 0.488 – 2.56 0.794 0 31602 exclusion phecode
327.1 Hypersomnia Neurological 1.02 0.451 – 2.33 0.953 0 19110 exclusion phecode
327.3 Sleep apnea Neurological 1.33 0.583 – 3.03 0.499 0 31304 exclusion phecode
327.31 Central/nonobstroctive sleep apnea Neurological 0.735 0.297 – 1.81 0.504 0 4784 exclusion phecode
327.32 Obstructive sleep apnea Neurological 1.31 0.574 – 2.97 0.525 0 30530 exclusion phecode
327.4 Insomnia Neurological 1.18 0.519 – 2.7 0.688 0 30960 exclusion phecode
327.41 Organic or persistent insomnia Neurological 0.615 0.257 – 1.47 0.275 0 12120 exclusion phecode
327.5 Parasomnia Neurological 0.674 0.286 – 1.59 0.367 0 5913 exclusion phecode
327.6 Circadian rhythm sleep disorder Neurological 1.22 0.531 – 2.79 0.641 0 2666 exclusion phecode
327.7 Sleep related movement disorders Neurological 1.38 0.587 – 3.22 0.463 0 17323 exclusion phecode
327.71 Restless legs syndrome Neurological 0.82 0.349 – 1.93 0.648 0 15360 exclusion phecode
327.72 Sleep related leg cramps Neurological 0.842 0.342 – 2.07 0.708 0 822 exclusion phecode
331 Other cerebral degenerations Neurological 0.92 0.822 – 1.03 0.145 330 5072 exclusion phecode
331.1 Hydrocephalus Neurological 0.959 0.817 – 1.12 0.606 164 2150 exclusion phecode
331.9 Cerebral degeneration, unspecified Neurological 0.868 0.74 – 1.02 0.081 163 2841 exclusion phecode
332 Parkinson's disease Neurological 0.89 0.753 – 1.05 0.174 146 2876 exclusion phecode
333
Extrapyramidal disease and abnormal movement
Extrapyramidal disease and abnormal movement disorders
 Neurological 0.978 0.9 – 1.06 0.608 576 19081 exclusion phecode
333.1 Essential tremor Neurological 0.95 0.84 – 1.07 0.409 268 4986 exclusion phecode
333.2 Myoclonus Neurological 0.876 0.661 – 1.16 0.358 45 1112 exclusion phecode
333.4 Torsion dystonia Neurological 0.858 0.722 – 1.02 0.0818 137 2566 exclusion phecode
333.8 Other degenerative diseases of the basal ganglia Neurological 0.852 0.584 – 1.24 0.406 26 608 exclusion phecode
334 Degenerative disease of the spinal cord Neurological 0.968 0.887 – 1.06 0.472 537 7624 exclusion phecode
334.1 Spinocerebellar disease Neurological 0.946 0.674 – 1.33 0.747 30 587 exclusion phecode
334.2 Anterior horn cell disease Neurological 0.889 0.683 – 1.16 0.379 56 769 exclusion phecode
334.21 Amyotrophic Lateral Sclerosis Neurological 1.03 0.742 – 1.43 0.857 39 497 exclusion phecode
335 Multiple sclerosis Neurological 0.967 0.837 – 1.12 0.652 193 2936 exclusion phecode
337 Disorders of the autonomic nervous system Neurological 1.01 0.903 – 1.13 0.867 328 5286 exclusion phecode
337.1 Peripheral autonomic neuropathy Neurological 0.997 0.834 – 1.19 0.971 125 2110 exclusion phecode
338 Pain Neurological 1.05 1.03 – 1.07 4.8e-05 11765 19871 exclusion phecode
338.1 Acute pain Neurological 1.04 1.02 – 1.07 0.000705 9209 19785 exclusion phecode
338.2 Chronic pain Neurological 1.07 1.03 – 1.1 6.1e-05 5268 19830 exclusion phecode
339 Other headache syndromes Neurological 1.08 1.04 – 1.11 1.26e-05 4551 25265 exclusion phecode
340 Migraine Neurological 1.08 1.04 – 1.12 2.39e-05 3394 22538 exclusion phecode
340.1 Migrain with aura Neurological 1.07 1.02 – 1.12 0.0082 1751 17715 exclusion phecode
341
Other demyelinating diseases of central nervous
Other demyelinating diseases of central nervous system
 Neurological 0.993 0.765 – 1.29 0.96 55 998 exclusion phecode
342 Hemiplegia Neurological 1.03 0.887 – 1.2 0.692 180 3282 exclusion phecode
343 Infantile cerebral palsy Neurological 1.05 0.791 – 1.4 0.728 54 663 exclusion phecode
344 Other paralytic syndromes Neurological 0.919 0.822 – 1.03 0.141 325 4928 exclusion phecode
345 Epilepsy, recurrent seizures, convulsions Neurological 1.08 1.02 – 1.15 0.00626 1320 18583 exclusion phecode
345.1 Epilepsy Neurological 1.03 0.924 – 1.15 0.579 343 5462 exclusion phecode
345.11 Generalized convulsive epilepsy Neurological 0.965 0.796 – 1.17 0.718 109 1752 exclusion phecode
345.12 Partial epilepsy Neurological 1.06 0.931 – 1.21 0.367 236 3893 exclusion phecode
345.3 Convulsions Neurological 1.08 1.02 – 1.15 0.00749 1230 17476 exclusion phecode
346
Abnormal findings on study of brain and/or
Abnormal findings on study of brain and/or nervous system
 Neurological 0.928 0.747 – 1.15 0.5 79 1300 exclusion phecode
346.1
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of skull and head
 Neurological 1.04 0.956 – 1.12 0.382 642 10425 exclusion phecode
346.2
Nonspecific abnormal results of function study
Nonspecific abnormal results of function study of brain and central nervous system
 Neurological 0.985 0.751 – 1.29 0.913 48 839 exclusion phecode
346.3
Nonspecific abnormal findings in cerebrospinal
Nonspecific abnormal findings in cerebrospinal fluid
 Neurological 0.985 0.747 – 1.3 0.913 47 776 exclusion phecode
347 Cataplexy and narcolepsy Neurological 0.585 0.272 – 1.25 0.168 2 746 exclusion phecode
348 Other conditions of brain Neurological 1.01 0.937 – 1.08 0.88 842 13032 exclusion phecode
348.2 Cerebral edema and compression of brain Neurological 0.995 0.907 – 1.09 0.92 491 6686 exclusion phecode
348.4 Cerebral cysts Neurological 0.982 0.817 – 1.18 0.85 120 1717 exclusion phecode
348.7 Coma Neurological 0.941 0.761 – 1.16 0.574 92 1634 exclusion phecode
348.8 Encephalopathy, not elsewhere classified Neurological 1.05 0.94 – 1.18 0.368 315 6032 exclusion phecode
348.9 Other conditions of brain, NOS Neurological 1 0.947 – 1.06 0.912 1252 16877 exclusion phecode
349
Other and unspecified disorders of the nervous
Other and unspecified disorders of the nervous system
 Neurological 0.977 0.887 – 1.08 0.631 455 6787 exclusion phecode
350 Abnormal movement Neurological 0.994 0.955 – 1.03 0.765 2802 27830 exclusion phecode
350.1 Abnormal involuntary movements Neurological 0.977 0.92 – 1.04 0.452 1150 21512 exclusion phecode
350.2 Abnormality of gait Neurological 1.01 0.959 – 1.06 0.725 1641 21342 exclusion phecode
350.3 Lack of coordination Neurological 0.942 0.853 – 1.04 0.235 422 7456 exclusion phecode
350.5 Abnormal reflex Neurological 0.962 0.767 – 1.21 0.738 85 1369 exclusion phecode
350.6 Disturbances of sensation of smell and taste Neurological 0.947 0.842 – 1.06 0.362 307 3842 exclusion phecode
351 Other peripheral nerve disorders Neurological 1.04 1 – 1.08 0.04 3323 25185 exclusion phecode
352 Disorders of other cranial nerves Neurological 1.01 0.946 – 1.08 0.778 1017 12383 exclusion phecode
352.1 Trigeminal nerve disorders [CN5] Neurological 0.991 0.872 – 1.13 0.894 253 3836 exclusion phecode
352.2 Facial nerve disorders [CN7] Neurological 1.01 0.916 – 1.11 0.851 460 5668 exclusion phecode
353 Nerve root and plexus disorders Neurological 1.03 0.985 – 1.08 0.185 1998 24247 exclusion phecode
353.1 Nerve plexus lesions Neurological 0.997 0.873 – 1.14 0.965 232 2888 exclusion phecode
353.2 Nerve root lesions Neurological 0.872 0.683 – 1.11 0.27 63 894 exclusion phecode
355 Complex regional/central pain syndrome Neurological 1.11 0.969 – 1.27 0.133 227 3840 exclusion phecode
355.1 Chronic pain syndrome Neurological 1.16 1.03 – 1.32 0.0182 263 6060 exclusion phecode
356 Hereditary and idiopathic peripheral neuropathy Neurological 1.03 0.963 – 1.11 0.364 861 14132 exclusion phecode
357 Inflammatory and toxic neuropathy Neurological 1.02 0.969 – 1.08 0.412 1420 20473 exclusion phecode
358 Myoneural disorders Neurological 1.06 0.959 – 1.17 0.257 412 7778 exclusion phecode
358.1 Myasthenia gravis Neurological 1.06 0.781 – 1.43 0.719 43 747 exclusion phecode
359 Muscular dystrophies and other myopathies Neurological 0.94 0.857 – 1.03 0.187 496 7794 exclusion phecode
359.1 Muscular dystrophies Neurological 1.06 0.749 – 1.5 0.743 37 426 exclusion phecode
359.2 Myopathy Neurological 0.925 0.842 – 1.02 0.109 467 7497 exclusion phecode
360 Disorders of the globe Sense Organs 0.921 0.711 – 1.19 0.533 58 855 exclusion phecode
360.2 Progressive myopia Sense Organs 0.874 0.621 – 1.23 0.441 31 436 exclusion phecode
361 Retinal detachments and defects Sense Organs 0.995 0.894 – 1.11 0.932 370 4720 exclusion phecode
361.1 Retinal detachment with retinal defect Sense Organs 1.07 0.908 – 1.26 0.418 158 1982 exclusion phecode
362 Other retinal disorders Sense Organs 0.973 0.923 – 1.03 0.309 1629 15592 exclusion phecode
362.2
Degeneration of macula and posterior pole of
Degeneration of macula and posterior pole of retina
 Sense Organs 0.962 0.9 – 1.03 0.253 1002 10425 exclusion phecode
362.21 Macular degeneration, dry Sense Organs 0.889 0.766 – 1.03 0.119 185 2367 exclusion phecode
362.22 Macular degeneration, wet Sense Organs 1.02 0.812 – 1.29 0.849 76 811 exclusion phecode
362.23 Cystoid macular degeneration of retina Sense Organs 1.11 0.951 – 1.29 0.185 182 2562 exclusion phecode
362.26 Macular puckering of retina Sense Organs 0.929 0.841 – 1.03 0.151 429 5798 exclusion phecode
362.27 Drusen (degenerative) of retina Sense Organs 0.966 0.84 – 1.11 0.631 211 3040 exclusion phecode
362.29 Macular degeneration (senile) of retina NOS Sense Organs 0.984 0.917 – 1.06 0.662 876 9382 exclusion phecode
362.3 Other nondiabetic retinopathy Sense Organs 0.982 0.886 – 1.09 0.724 411 5700 exclusion phecode
362.31 Separation of retinal layers Sense Organs 1.02 0.879 – 1.17 0.835 215 2668 exclusion phecode
362.4 Retinal vascular changes and abnomalities Sense Organs 1.03 0.911 – 1.15 0.674 299 4009 exclusion phecode
362.6 Peripheral retinal degenerations Sense Organs 0.937 0.801 – 1.09 0.41 170 2534 exclusion phecode
362.7 Hereditary retinal dystrophies Sense Organs 1.2 1.01 – 1.44 0.0418 122 1407 exclusion phecode
362.8 Retinal hemorrhage/ischemia Sense Organs 0.99 0.819 – 1.2 0.916 113 1588 exclusion phecode
362.9 Retinal edema Sense Organs 0.904 0.753 – 1.09 0.28 132 1899 exclusion phecode
363
Chorioretinal inflammations, scars, and other
Chorioretinal inflammations, scars, and other disorders of choroid
 Sense Organs 1.08 0.943 – 1.23 0.269 234 3222 exclusion phecode
363.3 Chorioretinal scars Sense Organs 1.12 0.939 – 1.33 0.214 144 2169 exclusion phecode
364 Corneal opacity and other disorders of cornea Sense Organs 0.994 0.912 – 1.08 0.897 568 7338 exclusion phecode
364.1 Corneal opacity Sense Organs 0.84 0.723 – 0.976 0.0229 191 2575 exclusion phecode
364.2 Corneal edema Sense Organs 0.953 0.738 – 1.23 0.712 60 819 exclusion phecode
364.4 Corneal degenerations Sense Organs 1.04 0.9 – 1.2 0.592 207 2699 exclusion phecode
364.41 Keratoconus Sense Organs 1.05 0.759 – 1.45 0.766 42 479 exclusion phecode
364.5 Corneal dystrophy Sense Organs 0.96 0.839 – 1.1 0.547 233 3149 exclusion phecode
364.51 Fuchs' dystrophy Sense Organs 0.976 0.811 – 1.17 0.795 121 1706 exclusion phecode
364.9 Cornea replaced by transplant Sense Organs 1.16 0.856 – 1.58 0.333 45 597 exclusion phecode
365 Glaucoma Sense Organs 0.974 0.921 – 1.03 0.358 1366 14384 exclusion phecode
365.1 Open-angle glaucoma Sense Organs 0.971 0.868 – 1.09 0.608 332 4367 exclusion phecode
365.11 Primary open angle glaucoma Sense Organs 0.981 0.85 – 1.13 0.798 200 2480 exclusion phecode
365.2 Primary angle-closure glaucoma Sense Organs 1.18 0.981 – 1.41 0.0793 125 1592 exclusion phecode
366 Cataract Sense Organs 0.959 0.925 – 0.995 0.0248 4148 19419 exclusion phecode
366.1 Nonsenile Cataract Sense Organs 0.891 0.72 – 1.1 0.285 91 1396 exclusion phecode
366.2 Senile cataract Sense Organs 0.923 0.882 – 0.965 0.000493 2379 17252 exclusion phecode
367
Disorders of refraction and accommodation
Disorders of refraction and accommodation; blindness and low vision
 Sense Organs 0.937 0.906 – 0.968 0.000115 4346 27281 exclusion phecode
367.1 Myopia Sense Organs 0.916 0.878 – 0.956 5.37e-05 2461 25018 exclusion phecode
367.2 Astigmatism Sense Organs 0.915 0.873 – 0.959 0.000183 2004 23245 exclusion phecode
367.8 Hypermetropia Sense Organs 0.939 0.878 – 1 0.0694 911 13009 exclusion phecode
367.9 Blindness and low vision Sense Organs 1.08 0.991 – 1.18 0.0784 586 8739 exclusion phecode
368 Visual disturbances Sense Organs 0.981 0.941 – 1.02 0.346 2596 27880 exclusion phecode
368.1 Amblyopia Sense Organs 1 0.895 – 1.12 0.988 336 4533 exclusion phecode
368.2 Diplopia and disorders of binocular vision Sense Organs 1.06 0.966 – 1.16 0.221 498 7402 exclusion phecode
368.3 Anisometropia Sense Organs 0.825 0.678 – 1 0.0544 107 1479 exclusion phecode
368.4 Visual field defects Sense Organs 0.936 0.853 – 1.03 0.166 493 7600 exclusion phecode
368.9 Subjective visual disturbances Sense Organs 0.94 0.849 – 1.04 0.241 391 7345 exclusion phecode
368.91 Psychophysical visual disturbances Sense Organs 1.06 0.748 – 1.51 0.734 30 788 exclusion phecode
369 Infection of the eye Sense Organs 0.915 0.867 – 0.966 0.00123 1464 20301 exclusion phecode
369.2 Eye infection, viral Sense Organs 0.839 0.736 – 0.957 0.00876 248 3512 exclusion phecode
369.5 Conjunctivitis, infectious Sense Organs 0.921 0.868 – 0.977 0.00603 1225 17900 exclusion phecode
370 Keratitis Sense Organs 0.976 0.901 – 1.06 0.548 656 9224 exclusion phecode
370.1 Corneal ulcer Sense Organs 1 0.84 – 1.2 0.969 125 1521 exclusion phecode
370.2 Superficial keratitis Sense Organs 0.873 0.768 – 0.993 0.0392 249 3805 exclusion phecode
370.3 Keratoconjunctivitis Sense Organs 1.04 0.92 – 1.17 0.557 290 4375 exclusion phecode
370.31 Keratoconjunctivitis sicca Sense Organs 0.876 0.674 – 1.14 0.322 54 1164 exclusion phecode
371 Inflammation of the eye Sense Organs 0.935 0.893 – 0.98 0.00489 2011 22717 exclusion phecode
371.1 Uveitis, noninfectious or NOS Sense Organs 1.01 0.887 – 1.14 0.92 255 3648 exclusion phecode
371.2 Conjunctivitis, noninfectious Sense Organs 0.924 0.834 – 1.02 0.125 399 6293 exclusion phecode
371.21 Allergic conjunctivitis Sense Organs 0.911 0.815 – 1.02 0.099 334 5272 exclusion phecode
371.3 Inflammation of eyelids Sense Organs 0.928 0.879 – 0.978 0.00565 1514 18819 exclusion phecode
371.33 Noninfectious dermatoses of eyelid Sense Organs 1.09 0.843 – 1.42 0.504 59 912 exclusion phecode
372 Disorders of conjunctiva Sense Organs 0.949 0.869 – 1.04 0.244 543 7370 exclusion phecode
374 Other disorders of eyelids Sense Organs 0.933 0.883 – 0.987 0.0161 1358 16792 exclusion phecode
374.1 Ectropion or entropion Sense Organs 0.897 0.786 – 1.02 0.104 242 2826 exclusion phecode
374.2 Lagophthalmos Sense Organs 1.07 0.904 – 1.27 0.432 144 1658 exclusion phecode
374.3 Ptosis of eyelid Sense Organs 0.921 0.841 – 1.01 0.0771 497 7400 exclusion phecode
374.6 Dermatochalasis Sense Organs 0.88 0.797 – 0.971 0.0114 423 6646 exclusion phecode
375 Disorders of lacrimal system Sense Organs 0.998 0.947 – 1.05 0.942 1595 18358 exclusion phecode
375.1 Dry eyes Sense Organs 0.982 0.934 – 1.03 0.478 1729 18843 exclusion phecode
375.2 Epiphora Sense Organs 0.993 0.864 – 1.14 0.916 212 3082 exclusion phecode
376 Disorders of the orbit Sense Organs 1.01 0.879 – 1.15 0.922 223 2509 exclusion phecode
377 Disorders of optic nerve and visual pathways Sense Organs 0.998 0.907 – 1.1 0.963 473 6403 exclusion phecode
377.1 Optic atrophy Sense Organs 0.823 0.692 – 0.978 0.027 145 1909 exclusion phecode
377.3 Optic neuritis/neuropathy Sense Organs 1.05 0.93 – 1.18 0.451 308 4126 exclusion phecode
378
Strabismus and other disorders of binocular eye
Strabismus and other disorders of binocular eye movements
 Sense Organs 0.941 0.867 – 1.02 0.144 632 8893 exclusion phecode
378.1 Strabismus (not specified as paralytic) Sense Organs 0.95 0.859 – 1.05 0.327 407 5834 exclusion phecode
378.2 Nystagmus and other irregular eye movements Sense Organs 1.13 0.915 – 1.41 0.251 87 1182 exclusion phecode
378.5 Paralytic strabismus Sense Organs 1 0.866 – 1.16 0.97 196 2423 exclusion phecode
379 Other disorders of eye Sense Organs 0.96 0.919 – 1 0.0699 2371 21029 exclusion phecode
379.1 Scleritis and episcleritis Sense Organs 0.927 0.739 – 1.16 0.508 83 1228 exclusion phecode
379.2 Disorders of vitreous body Sense Organs 0.938 0.891 – 0.989 0.0168 1648 16083 exclusion phecode
379.3 Aphakia and other disorders of lens Sense Organs 1.08 0.847 – 1.37 0.548 74 881 exclusion phecode
379.4 Anomalies of pupillary function Sense Organs 0.967 0.81 – 1.15 0.707 132 1989 exclusion phecode
379.5 Disorders of iris and ciliary body Sense Organs 1.08 0.912 – 1.27 0.379 153 2008 exclusion phecode
379.51 Pigmentary iris degeneration Sense Organs 0.856 0.611 – 1.2 0.365 35 517 exclusion phecode
379.9 Pain, swelling or discharge of eye Sense Organs 1.06 0.969 – 1.16 0.2 492 7883 exclusion phecode
380 Disorders of external ear Sense Organs 0.925 0.868 – 0.986 0.017 1026 13659 exclusion phecode
380.1 Otitis externa Sense Organs 0.962 0.888 – 1.04 0.335 648 9961 exclusion phecode
380.4 Impacted cerumen Sense Organs 0.911 0.858 – 0.967 0.00206 1192 15839 exclusion phecode
381 Otitis media and Eustachian tube disorders Sense Organs 0.982 0.939 – 1.03 0.423 2151 25723 exclusion phecode
381.1 Otitis media Sense Organs 1.02 0.965 – 1.07 0.554 1584 21227 exclusion phecode
381.11 Suppurative and unspecified otitis media Sense Organs 1.02 0.964 – 1.08 0.491 1332 18252 exclusion phecode
381.2 Eustachian tube disorders Sense Organs 0.927 0.864 – 0.994 0.0338 854 12424 exclusion phecode
381.3 Mastoiditis & related conditions Sense Organs 1.14 0.926 – 1.39 0.223 100 1043 exclusion phecode
381.9 Otorrhea Sense Organs 1.12 0.971 – 1.29 0.122 213 2616 exclusion phecode
382 Otalgia Sense Organs 0.997 0.929 – 1.07 0.931 831 13266 exclusion phecode
383 Otosclerosis Sense Organs 0.763 0.611 – 0.953 0.017 84 852 exclusion phecode
384 Other disorders of tympanic membrane Sense Organs 1.05 0.935 – 1.18 0.401 304 3712 exclusion phecode
384.1 Myringitis Sense Organs 1.21 0.847 – 1.73 0.296 28 361 exclusion phecode
384.4 Perforation of tympanic membrane Sense Organs 1.04 0.916 – 1.19 0.519 242 2910 exclusion phecode
385 Other disorders of middle ear and mastoid Sense Organs 0.978 0.867 – 1.1 0.725 295 3069 exclusion phecode
385.3 Cholesteatoma Sense Organs 1.02 0.884 – 1.17 0.808 214 1964 exclusion phecode
385.5
Tympanosclerosis and middle ear disease related
Tympanosclerosis and middle ear disease related to otitis media
 Sense Organs 0.891 0.71 – 1.12 0.318 82 855 exclusion phecode
386
Vertiginous syndromes and other disorders of
Vertiginous syndromes and other disorders of vestibular system
 Sense Organs 0.992 0.922 – 1.07 0.822 792 12768 exclusion phecode
386.1 Meniere's disease Sense Organs 0.999 0.854 – 1.17 0.994 163 2160 exclusion phecode
386.2 Peripheral or central vertigo Sense Organs 1.01 0.933 – 1.1 0.788 643 10774 exclusion phecode
386.21 Central origin vertigo Sense Organs 1.02 0.931 – 1.11 0.689 518 8233 exclusion phecode
386.3 Labyrinthitis Sense Organs 0.988 0.912 – 1.07 0.761 654 10166 exclusion phecode
386.9
Dizziness and giddiness (Light-headedness and
Dizziness and giddiness (Light-headedness and vertigo)
 Sense Organs 0.99 0.954 – 1.03 0.622 3050 27401 exclusion phecode
388 Other disorders of ear Sense Organs 1.04 0.951 – 1.15 0.365 477 6667 exclusion phecode
389 Hearing loss Sense Organs 0.989 0.956 – 1.02 0.514 4197 27094 exclusion phecode
389.1 Sensorineural hearing loss Sense Organs 0.957 0.912 – 1 0.0733 1880 20075 exclusion phecode
389.2 Conductive hearing loss Sense Organs 1.01 0.921 – 1.1 0.891 548 6415 exclusion phecode
389.3 Degenerative and vascular disorders of ear Sense Organs 0.846 0.675 – 1.06 0.146 82 1211 exclusion phecode
389.4 Tinnitus Sense Organs 0.918 0.862 – 0.978 0.00777 1063 15207 exclusion phecode
389.5 Disorders of acoustic nerve Sense Organs 0.976 0.758 – 1.26 0.849 62 847 exclusion phecode
394 Rheumatic disease of the heart valves Circulatory System 0.986 0.912 – 1.07 0.718 714 9161 exclusion phecode
394.1 Mitral valve stenosis and aortic valve stenosis Circulatory System 0.904 0.768 – 1.06 0.226 160 2267 exclusion phecode
394.2 Mitral valve disease Circulatory System 0.968 0.844 – 1.11 0.645 228 3097 exclusion phecode
394.3 Aortic valve disease Circulatory System 1.02 0.821 – 1.28 0.836 90 1139 exclusion phecode
394.4 Acute rheumatic heart disease Circulatory System 0.987 0.659 – 1.48 0.948 23 366 exclusion phecode
394.7 Disease of tricuspid valve Circulatory System 0.967 0.856 – 1.09 0.596 291 3892 exclusion phecode
395 Heart valve disorders Circulatory System 1.02 0.978 – 1.07 0.306 2008 19392 exclusion phecode
395.1 Nonrheumatic mitral valve disorders Circulatory System 1.01 0.95 – 1.07 0.748 1134 13774 exclusion phecode
395.2 Nonrheumatic aortic valve disorders Circulatory System 0.99 0.926 – 1.06 0.772 963 11412 exclusion phecode
395.3 Nonrheumatic tricuspid valve disorders Circulatory System 1.01 0.878 – 1.16 0.91 213 3292 exclusion phecode
395.4 Nonrheumatic pulmonary valve disorders Circulatory System 1.12 0.869 – 1.45 0.377 63 746 exclusion phecode
395.6 Heart valve replaced Circulatory System 0.973 0.893 – 1.06 0.537 583 7289 exclusion phecode
396 Abnormal heart sounds Circulatory System 1.03 0.989 – 1.08 0.148 2515 23755 exclusion phecode
401 Hypertension Circulatory System 1.09 1.07 – 1.12 7.22e-12 13289 18287 exclusion phecode
401.1 Essential hypertension Circulatory System 1.09 1.07 – 1.12 9.49e-12 13183 18284 exclusion phecode
401.2 Hypertensive heart and/or renal disease Circulatory System 1.1 1.04 – 1.17 0.00146 1464 11104 exclusion phecode
401.21 Hypertensive heart disease Circulatory System 1.11 0.981 – 1.25 0.0998 288 4986 exclusion phecode
401.22 Hypertensive chronic kidney disease Circulatory System 1.1 1.03 – 1.17 0.00488 1153 9923 exclusion phecode
401.3 Other hypertensive complications Circulatory System 1.07 1.01 – 1.14 0.028 1179 12055 exclusion phecode
411 Ischemic Heart Disease Circulatory System 1.09 1.05 – 1.13 1.06e-06 4283 21384 exclusion phecode
411.1 Unstable angina (intermediate coronary syndrome) Circulatory System 1.08 0.957 – 1.21 0.22 290 5885 exclusion phecode
411.2 Myocardial infarction Circulatory System 1.14 1.08 – 1.2 7.66e-07 1779 15102 exclusion phecode
411.3 Angina pectoris Circulatory System 1.09 1.02 – 1.16 0.0108 1001 12713 exclusion phecode
411.4 Coronary atherosclerosis Circulatory System 1.08 1.04 – 1.12 6.23e-05 3652 19228 exclusion phecode
411.41 Aneurysm and dissection of heart Circulatory System 1.21 0.939 – 1.55 0.142 66 1068 exclusion phecode
411.8
Other chronic ischemic heart disease
Other chronic ischemic heart disease, unspecified
 Circulatory System 1.1 1.05 – 1.14 1.01e-05 3048 17968 exclusion phecode
411.9
Other acute and subacute forms of ischemic
Other acute and subacute forms of ischemic heart disease
 Circulatory System 1.02 0.871 – 1.2 0.775 157 2913 exclusion phecode
414 Other forms of chronic heart disease Circulatory System 1.02 0.959 – 1.08 0.572 1265 15793 exclusion phecode
414.2 ASCVD Circulatory System 1.09 0.963 – 1.24 0.169 267 4738 exclusion phecode
415 Pulmonary heart disease Circulatory System 1.02 0.962 – 1.07 0.574 1444 20381 exclusion phecode
415.1 Acute pulmonary heart disease Circulatory System 1.03 0.964 – 1.1 0.361 913 12874 exclusion phecode
415.11 Pulmonary embolism and infarction, acute Circulatory System 1.03 0.966 – 1.11 0.333 912 12837 exclusion phecode
415.2 Chronic pulmonary heart disease Circulatory System 1.01 0.928 – 1.09 0.891 631 11728 exclusion phecode
415.21 Primary pulmonary hypertension Circulatory System 1.05 0.917 – 1.21 0.469 220 4675 exclusion phecode
416 Cardiomegaly Circulatory System 0.961 0.878 – 1.05 0.386 508 8340 exclusion phecode
418 Nonspecific chest pain Circulatory System 1.03 0.997 – 1.06 0.078 5921 25617 exclusion phecode
418.1 Precordial pain Circulatory System 1 0.918 – 1.1 0.95 523 10044 exclusion phecode
420 Carditis Circulatory System 0.997 0.924 – 1.08 0.944 734 10420 exclusion phecode
420.1 Myocarditis Circulatory System 0.733 0.548 – 0.981 0.0368 49 633 exclusion phecode
420.2 Pericarditis Circulatory System 1.06 0.958 – 1.18 0.244 383 5632 exclusion phecode
420.21 Acute pericarditis Circulatory System 0.939 0.752 – 1.17 0.579 82 1224 exclusion phecode
420.22 Chronic pericarditis Circulatory System 1.15 0.873 – 1.52 0.319 53 774 exclusion phecode
420.3 Endocarditis Circulatory System 0.963 0.863 – 1.07 0.501 343 4989 exclusion phecode
425 Cardiomyopathy Circulatory System 1.03 0.959 – 1.1 0.444 910 13136 exclusion phecode
425.1 Primary/intrinsic cardiomyopathies Circulatory System 1.03 0.961 – 1.1 0.405 865 12531 exclusion phecode
425.11 Hypertrophic obstructive cardiomyopathy Circulatory System 0.978 0.793 – 1.21 0.831 86 1359 exclusion phecode
425.12 Other hypertrophic cardiomyopathy Circulatory System 0.973 0.789 – 1.2 0.795 90 1328 exclusion phecode
425.2 Secondary/extrinsic cardiomyopathies Circulatory System 0.974 0.817 – 1.16 0.767 134 2144 exclusion phecode
425.8 Other cardiomyopathy Circulatory System 1.07 0.777 – 1.47 0.679 40 625 exclusion phecode
426 Cardiac conduction disorders Circulatory System 0.989 0.959 – 1.02 0.468 6022 19951 exclusion phecode
426.2 Atrioventricular [AV] block Circulatory System 0.939 0.872 – 1.01 0.0988 790 8728 exclusion phecode
426.21 First degree AV block Circulatory System 0.931 0.851 – 1.02 0.119 530 6726 exclusion phecode
426.22 Mobitz II AV block Circulatory System 0.875 0.604 – 1.27 0.482 26 435 exclusion phecode
426.23 Second degree AV block Circulatory System 0.822 0.666 – 1.01 0.0656 93 1466 exclusion phecode
426.24 Atrioventricular block, complete Circulatory System 0.972 0.842 – 1.12 0.701 198 2970 exclusion phecode
426.25 Other heart block Circulatory System 0.853 0.687 – 1.06 0.15 84 1379 exclusion phecode
426.3 Bundle branch block Circulatory System 1.04 0.973 – 1.11 0.265 1067 10598 exclusion phecode
426.31 Right bundle branch block Circulatory System 1.05 0.97 – 1.14 0.219 644 8181 exclusion phecode
426.32 Left bundle branch block Circulatory System 1.02 0.929 – 1.13 0.622 437 6150 exclusion phecode
426.4 Anomalous atrioventricular excitation Circulatory System 0.959 0.712 – 1.29 0.781 50 669 exclusion phecode
426.7 Abnormal electrocardiogram [ECG] [EKG] Circulatory System 0.983 0.951 – 1.02 0.297 4977 19715 exclusion phecode
426.8 Other cardiac conduction disorders Circulatory System 1.01 0.882 – 1.16 0.861 216 5082 exclusion phecode
426.9 Cardiac pacemaker/device in situ Circulatory System 0.951 0.884 – 1.02 0.181 814 8784 exclusion phecode
426.91 Cardiac pacemaker in situ Circulatory System 0.93 0.85 – 1.02 0.114 535 6253 exclusion phecode
426.92 Cardiac defibrillator in situ Circulatory System 0.948 0.849 – 1.06 0.336 351 5566 exclusion phecode
427 Cardiac dysrhythmias Circulatory System 0.987 0.962 – 1.01 0.319 9281 20206 exclusion phecode
427.1 Paroxysmal tachycardia, unspecified Circulatory System 0.96 0.903 – 1.02 0.187 1148 14005 exclusion phecode
427.11 Paroxysmal supraventricular tachycardia Circulatory System 0.983 0.912 – 1.06 0.645 766 11053 exclusion phecode
427.12 Paroxysmal ventricular tachycardia Circulatory System 0.924 0.843 – 1.01 0.0914 497 7527 exclusion phecode
427.2 Atrial fibrillation and flutter Circulatory System 0.968 0.925 – 1.01 0.159 2515 14218 exclusion phecode
427.21 Atrial fibrillation Circulatory System 0.966 0.922 – 1.01 0.138 2438 13993 exclusion phecode
427.22 Atrial flutter Circulatory System 0.908 0.839 – 0.983 0.017 693 8353 exclusion phecode
427.3 Other specified cardiac dysrhythmias Circulatory System 0.993 0.96 – 1.03 0.688 4417 20071 exclusion phecode
427.4 Cardiac arrest and ventricular fibrillation Circulatory System 0.999 0.872 – 1.14 0.986 224 4026 exclusion phecode
427.41 Ventricular fibrillation and flutter Circulatory System 0.823 0.667 – 1.02 0.0706 96 1605 exclusion phecode
427.42 Cardiac arrest Circulatory System 1.13 0.964 – 1.32 0.134 166 3108 exclusion phecode
427.5 Arrhythmia (cardiac) NOS Circulatory System 0.972 0.935 – 1.01 0.146 3246 19984 exclusion phecode
427.6 Premature beats Circulatory System 0.933 0.875 – 0.994 0.0329 1049 12328 exclusion phecode
427.61 Supraventricular premature beats Circulatory System 0.958 0.849 – 1.08 0.486 286 4759 exclusion phecode
427.7 Tachycardia NOS Circulatory System 1.01 0.97 – 1.06 0.568 2441 20034 exclusion phecode
427.8 Sinoatrial node dysfunction (Bradycardia) Circulatory System 0.957 0.865 – 1.06 0.399 405 5702 exclusion phecode
427.9 Palpitations Circulatory System 0.927 0.884 – 0.972 0.00163 1944 19116 exclusion phecode
428 Congestive heart failure; nonhypertensive Circulatory System 1.03 0.975 – 1.08 0.336 1766 17286 exclusion phecode
428.1 Congestive heart failure (CHF) NOS Circulatory System 1.03 0.979 – 1.09 0.23 1529 16369 exclusion phecode
428.2 Heart failure NOS Circulatory System 1.03 0.971 – 1.08 0.359 1484 15851 exclusion phecode
428.3
Heart failure with reduced EF [Systolic or
Heart failure with reduced EF [Systolic or combined heart failure]
 Circulatory System 1 0.928 – 1.09 0.93 681 10526 exclusion phecode
428.4
Heart failure with preserved EF [Diastolic
Heart failure with preserved EF [Diastolic heart failure]
 Circulatory System 0.999 0.913 – 1.09 0.984 523 9749 exclusion phecode
429
Ill-defined descriptions and complications of
Ill-defined descriptions and complications of heart disease
 Circulatory System 0.993 0.965 – 1.02 0.65 6139 24531 exclusion phecode
429.1 Heart transplant/surgery Circulatory System 1.03 0.938 – 1.12 0.578 537 8519 exclusion phecode
429.2 Abnormal function study of cardiovascular system Circulatory System 1.02 0.974 – 1.06 0.469 2647 21713 exclusion phecode
429.3 Symptoms involving cardiovascular system Circulatory System 0.994 0.962 – 1.03 0.698 4644 24456 exclusion phecode
429.9 Cardiac complications, not elsewhere classified Circulatory System 0.953 0.853 – 1.07 0.396 340 5239 exclusion phecode
430 Intracranial hemorrhage Circulatory System 1.04 0.94 – 1.16 0.422 385 5314 exclusion phecode
430.1 Subarachnoid hemorrhage Circulatory System 0.891 0.747 – 1.06 0.196 136 1784 exclusion phecode
430.2 Intracerebral hemorrhage Circulatory System 1.17 1.01 – 1.37 0.0409 182 2477 exclusion phecode
430.3 Subdural hemorrhage Circulatory System 1.06 0.888 – 1.26 0.525 134 1815 exclusion phecode
433 Cerebrovascular disease Circulatory System 1.06 1.02 – 1.11 0.00329 2768 21705 exclusion phecode
433.1 Occlusion and stenosis of precerebral arteries Circulatory System 1.06 0.987 – 1.13 0.114 943 10676 exclusion phecode
433.11
Occlusion of cerebral arteries, with cerebral
Occlusion of cerebral arteries, with cerebral infarction
 Circulatory System 1.06 0.876 – 1.29 0.532 115 1619 exclusion phecode
433.12 Cerebral atherosclerosis Circulatory System 1.17 0.841 – 1.64 0.346 32 526 exclusion phecode
433.2 Occlusion of cerebral arteries Circulatory System 1.06 0.997 – 1.12 0.0622 1212 14494 exclusion phecode
433.21
Cerebral artery occlusion, with cerebral
Cerebral artery occlusion, with cerebral infarction
 Circulatory System 1.06 0.998 – 1.13 0.0575 1169 14072 exclusion phecode
433.3 Cerebral ischemia Circulatory System 1.04 0.979 – 1.1 0.218 1326 15266 exclusion phecode
433.31 Transient cerebral ischemia Circulatory System 1.05 0.983 – 1.11 0.157 1153 13842 exclusion phecode
433.5 Cerebral aneurysm Circulatory System 1.14 1.01 – 1.29 0.0392 286 3179 exclusion phecode
433.6 Acute, but ill-defined cerebrovascular disease Circulatory System 0.965 0.823 – 1.13 0.655 163 2980 exclusion phecode
433.8 Late effects of cerebrovascular disease Circulatory System 0.985 0.871 – 1.11 0.813 280 4642 exclusion phecode
440 Atherosclerosis Circulatory System 1.08 1.01 – 1.15 0.0159 1126 13403 exclusion phecode
440.1 Atherosclerosis of renal artery Circulatory System 1.09 0.908 – 1.32 0.345 126 1600 exclusion phecode
440.2 Atherosclerosis of the extremities Circulatory System 1.08 1 – 1.17 0.0484 652 9197 exclusion phecode
440.21
Atherosclerosis of native arteries of the
Atherosclerosis of native arteries of the extremities with ulceration or gangrene
 Circulatory System 1.11 0.916 – 1.35 0.281 112 1696 exclusion phecode
440.22
Atherosclerosis of native arteries of the
Atherosclerosis of native arteries of the extremities with intermittent claudication
 Circulatory System 1.08 0.983 – 1.2 0.106 428 6503 exclusion phecode
440.9 Atherosclerosis of aorta Circulatory System 1.11 1 – 1.23 0.0433 400 5505 exclusion phecode
441 Vascular insufficiency of intestine Circulatory System 1.22 1.07 – 1.39 0.003 249 3477 exclusion phecode
441.1 Acute vascular insufficiency of intestine Circulatory System 1.16 0.954 – 1.41 0.137 106 1608 exclusion phecode
441.2 Chronic vascular insufficiency of intestine Circulatory System 1.38 1.1 – 1.74 0.0062 74 1042 exclusion phecode
442 Other aneurysm Circulatory System 1.04 0.98 – 1.09 0.214 1434 14577 exclusion phecode
442.1 Aortic aneurysm Circulatory System 1.03 0.966 – 1.1 0.354 1029 11146 exclusion phecode
442.11 Abdominal aortic aneurysm Circulatory System 1.04 0.957 – 1.13 0.356 630 7099 exclusion phecode
442.2 Aneurysm of iliac artery Circulatory System 1.02 0.837 – 1.24 0.846 105 1342 exclusion phecode
442.3 Aneurysm of artery of lower extremity Circulatory System 1.03 0.836 – 1.26 0.803 99 1207 exclusion phecode
442.4 Arterial dissection Circulatory System 0.999 0.796 – 1.25 0.991 76 1274 exclusion phecode
442.8 Aneurysm of other specified artery Circulatory System 1.09 0.944 – 1.25 0.251 223 2744 exclusion phecode
443 Peripheral vascular disease Circulatory System 1.05 0.99 – 1.1 0.112 1433 16981 exclusion phecode
443.1 Raynaud's syndrome Circulatory System 0.98 0.88 – 1.09 0.717 360 5178 exclusion phecode
443.7
Peripheral angiopathy in diseases classified
Peripheral angiopathy in diseases classified elsewhere
 Circulatory System 1.29 1.02 – 1.64 0.0339 73 1311 exclusion phecode
443.8 Other specified peripheral vascular diseases Circulatory System 1.07 1.01 – 1.14 0.0231 1202 14999 exclusion phecode
443.9 Peripheral vascular disease, unspecified Circulatory System 1.07 1 – 1.14 0.0346 1073 12750 exclusion phecode
444 Arterial embolism and thrombosis Circulatory System 1.1 0.994 – 1.21 0.0645 438 5734 exclusion phecode
444.1
Arterial embolism and thrombosis of lower
Arterial embolism and thrombosis of lower extremity artery
 Circulatory System 1.06 0.906 – 1.23 0.482 176 2042 exclusion phecode
444.2 Embolism and thrombosis of abdominal aorta Circulatory System 1.03 0.822 – 1.28 0.818 79 1042 exclusion phecode
446 Polyarteritis nodosa and allied conditions Circulatory System 0.968 0.842 – 1.11 0.649 218 3138 exclusion phecode
446.4 Wegener's granulomatosis Circulatory System 0.856 0.65 – 1.13 0.268 54 757 exclusion phecode
446.5 Giant cell arteritis Circulatory System 0.95 0.673 – 1.34 0.77 34 534 exclusion phecode
446.9 Arteritis NOS Circulatory System 0.984 0.828 – 1.17 0.852 138 1936 exclusion phecode
447 Other disorders of arteries and arterioles Circulatory System 1.06 1 – 1.12 0.0379 1311 15656 exclusion phecode
447.1 Stricture of artery Circulatory System 1.08 0.949 – 1.23 0.243 268 3545 exclusion phecode
447.7 Aortic ectasia Circulatory System 1.04 0.93 – 1.16 0.51 350 5373 exclusion phecode
448 Disease of capillaries Circulatory System 0.902 0.835 – 0.975 0.00971 686 8252 exclusion phecode
450 Noninfectious disorders of lymphatic channels Circulatory System 0.968 0.91 – 1.03 0.292 1127 13849 exclusion phecode
451 Phlebitis and thrombophlebitis Circulatory System 1.04 0.934 – 1.17 0.447 334 5335 exclusion phecode
451.2
Phlebitis and thrombophlebitis of lower
Phlebitis and thrombophlebitis of lower extremities
 Circulatory System 1.03 0.853 – 1.25 0.755 116 1775 exclusion phecode
452 Other venous embolism and thrombosis Circulatory System 1 0.961 – 1.04 0.928 2645 21968 exclusion phecode
452.1 Iatrogenic pulmonary embolism and infarction Circulatory System 1.06 0.855 – 1.31 0.598 93 2015 exclusion phecode
452.2 Deep vein thrombosis [DVT] Circulatory System 1.01 0.957 – 1.06 0.834 1775 19583 exclusion phecode
452.8 Postphlebitic syndrome Circulatory System 1.1 0.889 – 1.36 0.375 89 1128 exclusion phecode
453 Chronic venous hypertension Circulatory System 1.04 0.842 – 1.29 0.707 91 1566 exclusion phecode
454 Varicose veins Circulatory System 0.955 0.905 – 1.01 0.0937 1475 17889 exclusion phecode
454.1 Varicose veins of lower extremity Circulatory System 0.959 0.903 – 1.02 0.161 1231 15496 exclusion phecode
454.11 Varicose veins of lower extremity, symptomtic Circulatory System 0.967 0.895 – 1.04 0.39 712 10866 exclusion phecode
455 Hemorrhoids Circulatory System 0.964 0.925 – 1 0.0801 2638 21840 exclusion phecode
456 Chronic venous insufficiency [CVI] Circulatory System 0.94 0.888 – 0.995 0.0324 1308 18057 exclusion phecode
457
Encounter for long-term (current) use of
Encounter for long-term (current) use of anticoagulants, antithrombotics, aspirin
 Circulatory System 1.05 0.98 – 1.12 0.178 1045 10924 exclusion phecode
457.2
Encounter for long-term (current) use of
Encounter for long-term (current) use of antiplatelets/antithrombotics
 Circulatory System 1.07 0.906 – 1.27 0.421 152 2275 exclusion phecode
457.3 Encounter for long-term (current) use of aspirin Circulatory System 1.05 0.986 – 1.13 0.124 983 10471 exclusion phecode
458 Hypotension Circulatory System 1.03 0.986 – 1.07 0.192 2419 22996 exclusion phecode
458.1 Orthostatic hypotension Circulatory System 1 0.917 – 1.09 0.989 540 9191 exclusion phecode
458.2 Iatrogenic hypotension Circulatory System 1.06 0.968 – 1.16 0.217 529 7671 exclusion phecode
458.9 Hypotension NOS Circulatory System 1.03 0.988 – 1.08 0.154 2160 22199 exclusion phecode
459 Other disorders of circulatory system Circulatory System 1.03 0.99 – 1.06 0.161 3895 25118 exclusion phecode
459.1 Hemorrhage NOS Circulatory System 0.922 0.829 – 1.02 0.128 383 5732 exclusion phecode
459.7 Blood vessel replaced Circulatory System 0.992 0.918 – 1.07 0.843 693 9224 exclusion phecode
459.9 Circulatory disease NEC Circulatory System 1.03 0.996 – 1.07 0.0817 3236 24102 exclusion phecode
464 Acute sinusitis Respiratory 0.913 0.872 – 0.955 8.97e-05 2061 23729 exclusion phecode
465
Acute upper respiratory infections of multiple
Acute upper respiratory infections of multiple or unspecified sites
 Respiratory 0.934 0.904 – 0.964 3.17e-05 4540 26439 exclusion phecode
465.2 Acute pharyngitis Respiratory 0.955 0.916 – 0.995 0.0283 2616 24073 exclusion phecode
465.4 Acute laryngitis and tracheitis Respiratory 0.869 0.745 – 1.01 0.0758 178 3251 exclusion phecode
470 Septal Deviations/Turbinate Hypertrophy Respiratory 0.934 0.868 – 1 0.0658 787 13544 exclusion phecode
471 Nasal polyps Respiratory 0.905 0.813 – 1.01 0.0705 355 4450 exclusion phecode
472 Chronic pharyngitis and nasopharyngitis Respiratory 0.982 0.908 – 1.06 0.655 678 12872 exclusion phecode
473 Diseases of the larynx and vocal cords Respiratory 1.01 0.955 – 1.06 0.781 1487 18868 exclusion phecode
473.1 Chronic laryngitis Respiratory 1.18 0.829 – 1.67 0.361 28 504 exclusion phecode
473.3 Paralysis/spasm of vocal cords or larynx Respiratory 1.05 0.944 – 1.18 0.347 336 4658 exclusion phecode
473.4 Voice disturbance Respiratory 1.01 0.956 – 1.08 0.63 1160 16357 exclusion phecode
474 Acute and chronic tonsillitis Respiratory 0.973 0.885 – 1.07 0.562 475 6521 exclusion phecode
474.1 Acute tonsillitis Respiratory 0.965 0.837 – 1.11 0.623 202 2732 exclusion phecode
474.2 Chronic tonsillitis and adenoiditis Respiratory 0.975 0.876 – 1.08 0.636 368 5347 exclusion phecode
475 Chronic sinusitis Respiratory 0.971 0.927 – 1.02 0.21 2035 21174 exclusion phecode
475.9 Postnasal drip Respiratory 0.881 0.793 – 0.98 0.019 375 6715 exclusion phecode
476 Allergic rhinitis Respiratory 0.968 0.942 – 0.996 0.0228 6835 21346 exclusion phecode
477 Epistaxis or throat hemorrhage Respiratory 0.954 0.869 – 1.05 0.319 478 8446 exclusion phecode
478 Throat pain Respiratory 0.894 0.772 – 1.03 0.133 194 3217 exclusion phecode
479 Other upper respiratory disease Respiratory 1 0.959 – 1.04 0.984 2526 21291 exclusion phecode
480 Pneumonia Respiratory 1.01 0.975 – 1.06 0.477 2710 26810 exclusion phecode
480.1 Bacterial pneumonia Respiratory 0.922 0.839 – 1.01 0.0929 465 8034 exclusion phecode
480.11 Pneumococcal pneumonia Respiratory 0.891 0.777 – 1.02 0.101 218 3877 exclusion phecode
480.12 Pseudomonal pneumonia Respiratory 0.827 0.639 – 1.07 0.15 64 1072 exclusion phecode
480.13 MRSA pneumonia Respiratory 1.04 0.761 – 1.41 0.817 39 820 exclusion phecode
480.2 Viral pneumonia Respiratory 1.15 0.894 – 1.48 0.278 61 1349 exclusion phecode
480.3 Pneumonia due to fungus (mycoses) Respiratory 0.906 0.696 – 1.18 0.466 57 1132 exclusion phecode
480.5 Bronchopneumonia and lung abscess Respiratory 0.936 0.731 – 1.2 0.603 63 908 exclusion phecode
481 Influenza Respiratory 0.973 0.892 – 1.06 0.539 543 9455 exclusion phecode
483 Acute bronchitis and bronchiolitis Respiratory 0.965 0.912 – 1.02 0.217 1315 21406 exclusion phecode
495 Asthma Respiratory 1.05 1.02 – 1.08 0.00398 4643 24524 exclusion phecode
495.1 Chronic obstructive asthma Respiratory 1.03 0.863 – 1.23 0.73 127 2758 exclusion phecode
495.11 Chronic obstructive asthma with exacerbation Respiratory 0.586 0.346 – 0.995 0.048 12 545 exclusion phecode
495.2 Asthma with exacerbation Respiratory 0.945 0.875 – 1.02 0.15 692 11918 exclusion phecode
496 Chronic airway obstruction Respiratory 1.14 1.09 – 1.19 6.87e-10 2650 20124 exclusion phecode
496.1 Emphysema Respiratory 1.15 1.08 – 1.22 1.95e-05 1105 13479 exclusion phecode
496.2 Chronic bronchitis Respiratory 1.16 1.11 – 1.22 5.83e-10 1917 18781 exclusion phecode
496.21 Obstructive chronic bronchitis Respiratory 1.16 1.11 – 1.22 3.78e-09 1725 17871 exclusion phecode
496.3 Bronchiectasis Respiratory 0.943 0.827 – 1.08 0.386 241 3804 exclusion phecode
497 Bronchitis Respiratory 0.928 0.863 – 0.998 0.0437 788 13461 exclusion phecode
498 Acute bronchospasm Respiratory 0.921 0.793 – 1.07 0.283 182 3604 exclusion phecode
499 Cystic fibrosis Respiratory 0.979 0.77 – 1.25 0.864 70 1039 exclusion phecode
500 Lung disease due to external agents Respiratory 1.01 0.892 – 1.14 0.882 283 3785 exclusion phecode
500.1 Extrinsic allergic alveolitis Respiratory 1.06 0.749 – 1.51 0.726 33 631 exclusion phecode
500.2 Pneumoconiosis Respiratory 0.797 0.585 – 1.09 0.152 40 531 exclusion phecode
501 Pneumonitis due to inhalation of food or vomitus Respiratory 1.02 0.899 – 1.15 0.782 273 4257 exclusion phecode
502 Postinflammatory pulmonary fibrosis Respiratory 0.952 0.852 – 1.06 0.389 344 5592 exclusion phecode
503 Pulmonary congestion and hypostasis Respiratory 0.942 0.84 – 1.06 0.306 318 5663 exclusion phecode
504 Other alveolar and parietoalveolar pneumonopathy Respiratory 0.896 0.781 – 1.03 0.117 220 4012 exclusion phecode
504.1 Idiopathic fibrosing alveolitis Respiratory 0.99 0.806 – 1.22 0.926 97 2111 exclusion phecode
505 Other pulmonary inflamation or edema Respiratory 0.991 0.916 – 1.07 0.827 687 10803 exclusion phecode
506 Empyema and pneumothorax Respiratory 1 0.951 – 1.06 0.934 1600 17566 exclusion phecode
507 Pleurisy; pleural effusion Respiratory 0.999 0.945 – 1.06 0.964 1415 18143 exclusion phecode
508
Pulmonary collapse; interstitial and
Pulmonary collapse; interstitial and compensatory emphysema
 Respiratory 1.01 0.948 – 1.07 0.773 1094 15620 exclusion phecode
509 Respiratory failure, insufficiency, arrest Respiratory 1.08 1.03 – 1.14 0.00254 1695 20514 exclusion phecode
509.1 Respiratory failure Respiratory 1.14 1.06 – 1.23 0.000499 748 13079 exclusion phecode
509.2 Respiratory insufficiency Respiratory 1.06 0.965 – 1.17 0.223 458 8069 exclusion phecode
509.3
Pulmonary insufficiency or respiratory failure
Pulmonary insufficiency or respiratory failure following trauma and surgery
 Respiratory 1.09 1.01 – 1.17 0.0222 820 11433 exclusion phecode
509.8
Dependence on respirator [Ventilator] or
Dependence on respirator [Ventilator] or supplemental oxygen
 Respiratory 1.07 0.978 – 1.16 0.147 543 11824 exclusion phecode
510 Other diseases of lung Respiratory 0.989 0.949 – 1.03 0.597 2650 24582 exclusion phecode
510.2 Lung transplant Respiratory 0.946 0.713 – 1.25 0.7 50 1184 exclusion phecode
512 Other symptoms of respiratory system Respiratory 0.993 0.968 – 1.02 0.576 9017 22633 exclusion phecode
512.1 Wheezing Respiratory 0.959 0.873 – 1.05 0.376 465 10668 exclusion phecode
512.2 Painful respiration Respiratory 1.03 0.958 – 1.1 0.47 889 16983 exclusion phecode
512.3 Abnormal chest sounds Respiratory 1.04 0.856 – 1.27 0.689 101 2246 exclusion phecode
512.7 Shortness of breath Respiratory 1.03 0.994 – 1.06 0.103 4264 22565 exclusion phecode
512.8 Cough Respiratory 0.965 0.933 – 0.999 0.0413 4129 22628 exclusion phecode
512.9 Other dyspnea Respiratory 0.994 0.961 – 1.03 0.724 4289 22585 exclusion phecode
513 Respiratory abnormalities Respiratory 1.01 0.984 – 1.04 0.374 5625 26003 exclusion phecode
513.3 Hypoventilation Respiratory 1.05 0.898 – 1.23 0.532 162 6405 exclusion phecode
513.31 Apnea Respiratory 1.18 0.901 – 1.54 0.23 50 3411 exclusion phecode
513.32 Orthopnea Respiratory 1.16 0.889 – 1.52 0.27 57 1580 exclusion phecode
513.4 Hyperventilation Respiratory 1.12 0.977 – 1.29 0.102 211 3891 exclusion phecode
513.8 Disorders of diaphragm Respiratory 0.92 0.75 – 1.13 0.425 103 1923 exclusion phecode
514 Abnormal findings examination of lungs Respiratory 0.991 0.953 – 1.03 0.654 2902 23479 exclusion phecode
514.1
Abnormal results of function study of pulmonary
Abnormal results of function study of pulmonary system
 Respiratory 1.03 0.821 – 1.3 0.788 80 1713 exclusion phecode
514.2 Solitary pulmonary nodule Respiratory 0.982 0.933 – 1.03 0.494 1647 18146 exclusion phecode
516 Abnormal sputum Respiratory 0.985 0.877 – 1.11 0.8 308 4787 exclusion phecode
516.1 Hemoptysis Respiratory 1.01 0.888 – 1.15 0.895 255 3972 exclusion phecode
519
Other diseases of respiratory system, not
Other diseases of respiratory system, not elsewhere classified
 Respiratory 1.02 0.985 – 1.06 0.253 3248 27380 exclusion phecode
519.1 Tracheostomy complications Respiratory 1.25 1.03 – 1.52 0.0227 118 1466 exclusion phecode
519.2 Respiratory complications Respiratory 1.17 1.02 – 1.35 0.0265 221 3080 exclusion phecode
519.8 Other diseases of respiratory system, NEC Respiratory 0.96 0.89 – 1.04 0.288 728 10864 exclusion phecode
519.9
Symptoms involving respiratory system and other
Symptoms involving respiratory system and other chest symptoms
 Respiratory 1.04 0.994 – 1.08 0.0898 2384 23773 exclusion phecode
520 Disorders of tooth development Digestive 1.09 0.951 – 1.24 0.222 237 2684 exclusion phecode
520.1 Hereditary disturbances in tooth structure Digestive 1.08 0.881 – 1.32 0.459 108 1116 exclusion phecode
520.2 Disturbances in tooth eruption Digestive 1.1 0.928 – 1.31 0.269 140 1657 exclusion phecode
521 Diseases of hard tissues of teeth Digestive 1.14 1.04 – 1.25 0.00488 512 6171 exclusion phecode
521.1 Dental caries Digestive 1.14 1.04 – 1.25 0.0076 475 5732 exclusion phecode
521.2 Dental abrasion, erosion and attrition Digestive 1.13 0.77 – 1.67 0.525 28 364 exclusion phecode
522 Diseases of pulp and periapical tissues Digestive 1.14 1 – 1.3 0.0502 228 3686 exclusion phecode
522.5 Periapical abscess Digestive 1.15 0.994 – 1.33 0.0597 191 3161 exclusion phecode
523 Gingival and periodontal diseases Digestive 1.06 0.948 – 1.18 0.322 362 4900 exclusion phecode
523.1 Gingivitis Digestive 0.968 0.76 – 1.23 0.795 71 980 exclusion phecode
523.3 Periodontitis (acute or chronic) Digestive 1.04 0.896 – 1.21 0.601 178 2475 exclusion phecode
523.31 Acute periodontitis Digestive 1.01 0.857 – 1.18 0.942 157 2136 exclusion phecode
523.32 Chronic periodontitis Digestive 0.965 0.754 – 1.24 0.778 65 791 exclusion phecode
524 Dentofacial anomalies, including malocclusion Digestive 0.983 0.856 – 1.13 0.814 216 2734 exclusion phecode
524.3 Anomalies of tooth position/malocclusion Digestive 0.961 0.803 – 1.15 0.667 124 1739 exclusion phecode
525
Other diseases of the teeth and supporting
Other diseases of the teeth and supporting structures
 Digestive 1.05 0.959 – 1.14 0.305 536 7257 exclusion phecode
525.1 Loss of teeth or edentulism Digestive 1.01 0.875 – 1.16 0.919 219 2619 exclusion phecode
526 Diseases of the jaws Digestive 0.992 0.939 – 1.05 0.761 1433 18571 exclusion phecode
526.1 Cysts of the jaws Digestive 0.975 0.834 – 1.14 0.747 172 1723 exclusion phecode
526.3 Anomalies of jaw size/symmetry Digestive 0.935 0.785 – 1.11 0.448 132 1876 exclusion phecode
526.4 Temporomandibular joint disorders Digestive 1 0.93 – 1.08 0.973 757 10617 exclusion phecode
526.41 Temporomandibular joint disorder, unspecified Digestive 1.01 0.927 – 1.1 0.853 604 8418 exclusion phecode
526.42 Arthralgia/ankylosis of temporomandibular joint Digestive 1.01 0.915 – 1.12 0.791 399 5402 exclusion phecode
526.5 Inflammatory conditions of jaw Digestive 0.992 0.849 – 1.16 0.924 179 1936 exclusion phecode
526.8 Exostosis of jaw Digestive 0.927 0.655 – 1.31 0.667 32 337 exclusion phecode
526.9 Jaw disease NOS Digestive 0.989 0.878 – 1.12 0.862 306 3325 exclusion phecode
527 Diseases of the salivary glands Digestive 0.988 0.924 – 1.06 0.721 950 11914 exclusion phecode
527.1 Hypertrophy of salivary gland Digestive 1.22 0.856 – 1.75 0.27 32 368 exclusion phecode
527.2 Sialoadenitis Digestive 0.883 0.765 – 1.02 0.092 203 2653 exclusion phecode
527.7 Disturbance of salivary secretion Digestive 0.991 0.901 – 1.09 0.847 459 6239 exclusion phecode
527.8 Other specified diseases of the salivary glands Digestive 1.11 0.939 – 1.31 0.219 158 1662 exclusion phecode
528
Diseases of the oral soft tissues, excluding
Diseases of the oral soft tissues, excluding lesions specific for gingiva and tongue
 Digestive 0.938 0.888 – 0.992 0.0237 1396 17850 exclusion phecode
528.1 Stomatitis and mucositis Digestive 0.946 0.844 – 1.06 0.345 319 4603 exclusion phecode
528.11 Stomatitis and mucositis (ulcerative) Digestive 1.03 0.846 – 1.26 0.744 104 1492 exclusion phecode
528.12 Oral aphthae Digestive 0.99 0.802 – 1.22 0.927 87 1495 exclusion phecode
528.3 Cellulitis and abscess of oral soft tissues Digestive 0.987 0.823 – 1.18 0.889 128 1582 exclusion phecode
528.4 Cysts of oral soft tissues Digestive 1.12 0.893 – 1.42 0.318 77 829 exclusion phecode
528.41 Cyst of the salivary gland Digestive 1.04 0.784 – 1.37 0.803 53 534 exclusion phecode
528.5 Diseases of lips Digestive 0.764 0.665 – 0.878 0.000142 225 3099 exclusion phecode
528.6 Leukoplakia of oral mucosa Digestive 0.846 0.685 – 1.05 0.122 89 919 exclusion phecode
528.7 Sialolithiasis Digestive 0.898 0.728 – 1.11 0.319 95 1087 exclusion phecode
529 Diseases and other conditions of the tongue Digestive 1.02 0.913 – 1.14 0.731 349 4594 exclusion phecode
529.1 Glossitis Digestive 1.05 0.817 – 1.35 0.702 63 868 exclusion phecode
529.6 Glossodynia Digestive 0.937 0.747 – 1.17 0.57 82 1100 exclusion phecode
530 Diseases of esophagus Digestive 1.09 1.06 – 1.11 1.79e-10 8992 21501 exclusion phecode
530.1 Esophagitis, GERD and related diseases Digestive 1.09 1.06 – 1.12 3.46e-11 8628 21501 exclusion phecode
530.11 GERD Digestive 1.1 1.07 – 1.13 1.9e-12 8367 21500 exclusion phecode
530.12 Ulcer of esophagus Digestive 1.08 0.924 – 1.25 0.343 175 2931 exclusion phecode
530.13 Barrett's esophagus Digestive 1.04 0.932 – 1.15 0.506 363 5485 exclusion phecode
530.14 Reflux esophagitis Digestive 1.07 0.989 – 1.15 0.0942 742 13076 exclusion phecode
530.15 Eosinophilic esophagitis Digestive 0.934 0.776 – 1.12 0.468 127 1686 exclusion phecode
530.2 Esophageal bleeding (varices/hemorrhage) Digestive 1.01 0.899 – 1.13 0.883 318 4752 exclusion phecode
530.3 Stricture and stenosis of esophagus Digestive 1.08 0.982 – 1.19 0.113 490 6671 exclusion phecode
530.5 Disorders of esophageal motility Digestive 1.02 0.896 – 1.17 0.746 246 4052 exclusion phecode
530.6 Diverticulum of esophagus, acquired Digestive 0.867 0.695 – 1.08 0.207 89 931 exclusion phecode
530.7 Gastroesophageal laceration-hemorrhage syndrome Digestive 1.05 0.768 – 1.44 0.753 38 601 exclusion phecode
530.9 Heartburn Digestive 1.02 0.94 – 1.1 0.664 661 11261 exclusion phecode
531 Peptic ulcer (excl. esophageal) Digestive 1.03 0.963 – 1.1 0.408 965 13693 exclusion phecode
531.1 Hemorrhage from gastrointestinal ulcer Digestive 1.03 0.881 – 1.2 0.712 173 2507 exclusion phecode
531.2 Gastric ulcer Digestive 1.03 0.939 – 1.12 0.569 544 7924 exclusion phecode
531.3 Duodenal ulcer Digestive 1.06 0.923 – 1.22 0.41 224 3024 exclusion phecode
531.4 Peptic ulcer, site unspecified Digestive 1.04 0.926 – 1.16 0.538 323 5267 exclusion phecode
531.5 Gastrojejunal ulcer Digestive 0.957 0.748 – 1.22 0.724 67 1031 exclusion phecode
532 Dysphagia Digestive 1.08 1.04 – 1.13 0.000187 2804 20571 exclusion phecode
535 Gastritis and duodenitis Digestive 1.03 0.974 – 1.09 0.292 1255 19104 exclusion phecode
535.1 Acute gastritis Digestive 1.02 0.932 – 1.11 0.679 533 8143 exclusion phecode
535.2 Atrophic gastritis Digestive 0.997 0.847 – 1.17 0.973 152 2439 exclusion phecode
535.6 Duodenitis Digestive 1.04 0.881 – 1.22 0.665 153 2273 exclusion phecode
535.8 Other specified gastritis Digestive 0.968 0.85 – 1.1 0.621 245 4386 exclusion phecode
535.9 Gastritis and duodenitis, NOS Digestive 0.998 0.914 – 1.09 0.958 543 8703 exclusion phecode
536 Disorders of function of stomach Digestive 1.02 0.963 – 1.08 0.501 1261 19432 exclusion phecode
536.3 Gastroparesis Digestive 1.13 0.999 – 1.28 0.0514 277 4719 exclusion phecode
536.7
Complications of gastrostomy, colostomy and
Complications of gastrostomy, colostomy and enterostomy
 Digestive 1.11 0.961 – 1.29 0.152 202 2844 exclusion phecode
536.8
Dyspepsia and other specified disorders of
Dyspepsia and other specified disorders of function of stomach
 Digestive 0.975 0.911 – 1.04 0.471 897 14687 exclusion phecode
537 Other disorders of stomach and duodenum Digestive 1.05 0.996 – 1.11 0.068 1358 20957 exclusion phecode
537.1 Lesions of stomach and duodenum Digestive 1.15 0.894 – 1.48 0.279 63 1118 exclusion phecode
539 Bariatric surgery Digestive 1.03 0.94 – 1.13 0.509 471 10283 exclusion phecode
540 Appendiceal conditions Digestive 1.05 0.929 – 1.2 0.411 259 3369 exclusion phecode
540.1 Appendicitis Digestive 1.07 0.937 – 1.23 0.31 219 2891 exclusion phecode
540.11 Acute appendicitis Digestive 1.07 0.922 – 1.24 0.367 184 2398 exclusion phecode
550 Abdominal hernia Digestive 1.04 1.01 – 1.08 0.0189 3549 26166 exclusion phecode
550.1 Inguinal hernia Digestive 0.955 0.895 – 1.02 0.161 1032 11031 exclusion phecode
550.2 Diaphragmatic hernia Digestive 1.05 0.995 – 1.11 0.0763 1329 17413 exclusion phecode
550.3 Femoral hernia Digestive 1.17 0.932 – 1.46 0.178 79 877 exclusion phecode
550.4 Umbilical hernia Digestive 0.991 0.912 – 1.08 0.826 621 8903 exclusion phecode
550.5 Ventral hernia Digestive 1.09 1.03 – 1.16 0.0051 1147 15008 exclusion phecode
550.6 Incisional hernia Digestive 1.03 0.951 – 1.12 0.449 631 8905 exclusion phecode
555
Inflammatory bowel disease and other
Inflammatory bowel disease and other gastroenteritis and colitis
 Digestive 1.07 1 – 1.15 0.0453 899 11637 exclusion phecode
555.1 Regional enteritis Digestive 1.01 0.925 – 1.11 0.798 534 7044 exclusion phecode
555.2 Ulcerative colitis Digestive 1.09 1 – 1.2 0.0484 553 7140 exclusion phecode
555.21 Ulcerative colitis (chronic) Digestive 1.03 0.913 – 1.15 0.673 314 4145 exclusion phecode
556 Ulceration of the lower GI tract Digestive 1.13 1 – 1.28 0.0461 283 4691 exclusion phecode
556.1 Ulceration of intestine Digestive 1.14 0.999 – 1.29 0.0518 245 4100 exclusion phecode
556.11
Angiodysplasia of intestine (without mention of
Angiodysplasia of intestine (without mention of hemorrhage)
 Digestive 1 0.809 – 1.24 0.981 85 1506 exclusion phecode
557 Intestinal malabsorption (non-celiac) Digestive 1.02 0.943 – 1.1 0.646 707 12820 exclusion phecode
557.1 Celiac disease Digestive 0.944 0.828 – 1.08 0.392 243 3133 exclusion phecode
558 Noninfectious gastroenteritis Digestive 1.07 1.02 – 1.13 0.00914 1625 20301 exclusion phecode
559 Ileostomy status Digestive 1.07 0.985 – 1.17 0.109 600 7238 exclusion phecode
560 Intestinal obstruction without mention of hernia Digestive 1.03 0.98 – 1.09 0.229 1622 18787 exclusion phecode
560.1 Paralytic ileus Digestive 1.02 0.954 – 1.09 0.54 899 11687 exclusion phecode
560.2 Impaction of intestine Digestive 1.13 0.966 – 1.33 0.126 166 2897 exclusion phecode
560.3 Peritoneal or intestinal adhesions Digestive 0.975 0.821 – 1.16 0.769 137 1969 exclusion phecode
560.4 Other intestinal obstruction Digestive 1 0.933 – 1.07 0.993 881 12189 exclusion phecode
561 Symptoms involving digestive system Digestive 1.07 1.01 – 1.14 0.0205 1208 16650 exclusion phecode
562 Diverticulosis and diverticulitis Digestive 0.981 0.942 – 1.02 0.361 2897 17434 exclusion phecode
562.1 Diverticulosis Digestive 0.98 0.941 – 1.02 0.337 2870 17401 exclusion phecode
562.2 Diverticulitis Digestive 1.04 0.965 – 1.12 0.304 767 11173 exclusion phecode
564 Functional digestive disorders Digestive 1.04 1.01 – 1.07 0.0153 5778 22006 exclusion phecode
564.1 Irritable Bowel Syndrome Digestive 1.05 0.995 – 1.1 0.0777 1617 17203 exclusion phecode
564.9 Personal history of diseases of digestive system Digestive 1.02 0.964 – 1.07 0.542 1522 19646 exclusion phecode
565 Anal and rectal conditions Digestive 0.993 0.945 – 1.04 0.791 1692 21910 exclusion phecode
565.1 Anal and rectal polyp Digestive 1.01 0.926 – 1.1 0.853 587 8670 exclusion phecode
567 Peritonitis and retroperitoneal infections Digestive 1.01 0.939 – 1.1 0.715 709 9608 exclusion phecode
568 Other disorders of peritoneum Digestive 1.05 0.986 – 1.12 0.123 980 12077 exclusion phecode
568.1
Peritoneal adhesions (postoperative)
Peritoneal adhesions (postoperative) (postinfection)
 Digestive 1.06 0.979 – 1.14 0.157 745 8805 exclusion phecode
569 Other disorders of intestine Digestive 1.03 0.992 – 1.06 0.135 3962 25434 exclusion phecode
569.1 Toxic gastroenteritis and colitis Digestive 0.956 0.811 – 1.13 0.598 151 2297 exclusion phecode
569.2 Gastrointestinal complications Digestive 1.03 0.949 – 1.11 0.515 694 9848 exclusion phecode
571 Chronic liver disease and cirrhosis Digestive 1.03 0.987 – 1.08 0.166 2123 23398 exclusion phecode
571.5 Other chronic nonalcoholic liver disease Digestive 1.04 0.99 – 1.09 0.123 1990 23120 exclusion phecode
571.51 Cirrhosis of liver without mention of alcohol Digestive 1.11 1.02 – 1.22 0.0229 490 7049 exclusion phecode
571.6 Primary biliary cirrhosis Digestive 0.99 0.802 – 1.22 0.927 91 1261 exclusion phecode
571.8
Liver abscess and sequelae of chronic liver
Liver abscess and sequelae of chronic liver disease
 Digestive 0.995 0.904 – 1.1 0.921 467 6602 exclusion phecode
571.81 Portal hypertension Digestive 1.04 0.924 – 1.18 0.492 285 3976 exclusion phecode
572 Ascites (non malignant) Digestive 1.05 0.989 – 1.11 0.114 1257 16106 exclusion phecode
573 Other disorders of liver Digestive 1.01 0.973 – 1.05 0.535 2774 24245 exclusion phecode
573.1 Chronic passive congestion of liver Digestive 1.07 0.803 – 1.44 0.628 47 999 exclusion phecode
573.2 Liver replaced by transplant Digestive 1.08 0.901 – 1.3 0.397 128 2044 exclusion phecode
573.3 Hepatomegaly Digestive 1.05 0.924 – 1.2 0.443 253 3298 exclusion phecode
573.4 Acute and subacute necrosis of liver Digestive 0.882 0.741 – 1.05 0.158 141 2249 exclusion phecode
573.5 Jaundice (not of newborn) Digestive 0.999 0.912 – 1.09 0.984 512 6673 exclusion phecode
573.6
Nonspecific elevation of levels of transaminase
Nonspecific elevation of levels of transaminase or lactic acid dehydrogenase [LDH]
 Digestive 0.991 0.934 – 1.05 0.768 1177 18873 exclusion phecode
573.7 Abnormal results of function study of liver Digestive 0.974 0.919 – 1.03 0.362 1253 19714 exclusion phecode
573.9 Abnormal serum enzyme levels Digestive 0.983 0.94 – 1.03 0.468 2072 24482 exclusion phecode
574 Cholelithiasis and cholecystitis Digestive 0.958 0.91 – 1.01 0.104 1589 21044 exclusion phecode
574.1 Cholelithiasis Digestive 0.943 0.894 – 0.996 0.0343 1445 19706 exclusion phecode
574.11 Cholelithiasis with acute cholecystitis Digestive 0.816 0.691 – 0.965 0.0174 158 2283 exclusion phecode
574.12 Cholelithiasis with other cholecystitis Digestive 0.902 0.797 – 1.02 0.101 272 3741 exclusion phecode
574.2 Calculus of bile duct Digestive 0.933 0.842 – 1.03 0.183 405 5878 exclusion phecode
574.3 Cholecystitis without cholelithiasis Digestive 0.94 0.848 – 1.04 0.239 389 5490 exclusion phecode
575 Other biliary tract disease Digestive 1.01 0.949 – 1.07 0.781 1161 15309 exclusion phecode
575.1 Cholangitis Digestive 0.992 0.858 – 1.15 0.916 197 2383 exclusion phecode
575.2 Obstruction of bile duct Digestive 0.987 0.885 – 1.1 0.808 356 4125 exclusion phecode
575.6 Cholesterolosis of gallbladder Digestive 0.993 0.823 – 1.2 0.946 111 1406 exclusion phecode
575.7 Other disorders of gallbladder Digestive 0.977 0.887 – 1.08 0.633 448 6360 exclusion phecode
575.8 Other disorders of biliary tract Digestive 1.01 0.932 – 1.1 0.749 601 7776 exclusion phecode
575.9
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of biliary tract
 Digestive 1.01 0.842 – 1.21 0.908 126 1757 exclusion phecode
577 Diseases of pancreas Digestive 1.01 0.949 – 1.07 0.795 1177 14525 exclusion phecode
577.1 Acute pancreatitis Digestive 1.04 0.955 – 1.13 0.377 590 7947 exclusion phecode
577.2 Chronic pancreatitis Digestive 1.06 0.929 – 1.2 0.407 255 3280 exclusion phecode
577.3 Cyst and pseudocyst of pancreas Digestive 0.955 0.849 – 1.07 0.441 316 3596 exclusion phecode
578 Gastrointestinal hemorrhage Digestive 1.03 0.985 – 1.08 0.194 2021 26415 exclusion phecode
578.1 Hematemesis Digestive 1.09 0.949 – 1.26 0.216 210 3378 exclusion phecode
578.2 Blood in stool Digestive 0.999 0.941 – 1.06 0.977 1165 18575 exclusion phecode
578.8 Hemorrhage of rectum and anus Digestive 1 0.939 – 1.07 0.922 942 15373 exclusion phecode
578.9 Hemorrhage of gastrointestinal tract Digestive 1.08 0.996 – 1.17 0.0631 662 10617 exclusion phecode
579 Other symptoms involving abdomen and pelvis Digestive 0.998 0.955 – 1.04 0.919 2291 24368 exclusion phecode
579.2 Splenomegaly Digestive 0.977 0.873 – 1.09 0.687 325 5112 exclusion phecode
579.8 Nonspecific abnormal findings in stool contents Digestive 0.976 0.895 – 1.06 0.583 556 9590 exclusion phecode
580 Nephritis; nephrosis; renal sclerosis Genitourinary 1.04 0.969 – 1.12 0.274 849 10883 exclusion phecode
580.1 Glomerulonephritis Genitourinary 0.989 0.847 – 1.15 0.889 178 2769 exclusion phecode
580.11 Proliferative glomerulonephritis Genitourinary 1.02 0.812 – 1.29 0.842 81 1008 exclusion phecode
580.12 Non-proliferative glomerulonephritis Genitourinary 0.982 0.75 – 1.29 0.898 55 800 exclusion phecode
580.13 Acute glomerulonephritis, NOS Genitourinary 1.07 0.701 – 1.62 0.766 22 425 exclusion phecode
580.14 Chronic glomerulonephritis, NOS Genitourinary 1.01 0.836 – 1.22 0.926 123 1931 exclusion phecode
580.2
Nephrotic syndrome without mention of
Nephrotic syndrome without mention of glomerulonephritis
 Genitourinary 1.15 0.935 – 1.41 0.189 102 1543 exclusion phecode
580.3
Nephritis and nephropathy without mention of
Nephritis and nephropathy without mention of glomerulonephritis
 Genitourinary 1.02 0.935 – 1.1 0.721 641 8386 exclusion phecode
580.31
Nephritis and nephropathy in diseases
Nephritis and nephropathy in diseases classified elsewhere
 Genitourinary 1 0.899 – 1.11 0.983 387 5001 exclusion phecode
580.32
Nephritis and nephropathy with pathological
Nephritis and nephropathy with pathological lesion
 Genitourinary 1.01 0.9 – 1.13 0.882 322 4620 exclusion phecode
580.4 Renal sclerosis, NOS Genitourinary 1.17 1.01 – 1.36 0.0397 196 2356 exclusion phecode
585 Renal failure Genitourinary 1.07 1.03 – 1.11 0.000583 3641 23150 exclusion phecode
585.1 Acute renal failure Genitourinary 1.07 1.02 – 1.12 0.00528 1883 19216 exclusion phecode
585.2 Renal failure NOS Genitourinary 1 0.9 – 1.12 0.942 356 5718 exclusion phecode
585.3 Chronic renal failure [CKD] Genitourinary 1.07 1.02 – 1.11 0.00247 2681 20825 exclusion phecode
585.31 Renal dialysis Genitourinary 1.04 0.932 – 1.16 0.473 353 5164 exclusion phecode
585.32 End stage renal disease Genitourinary 1.07 0.979 – 1.18 0.13 492 6853 exclusion phecode
585.33 Chronic Kidney Disease, Stage III Genitourinary 1.04 0.984 – 1.1 0.165 1380 14796 exclusion phecode
585.34 Chronic Kidney Disease, Stage IV Genitourinary 1.13 1.02 – 1.25 0.0144 438 6419 exclusion phecode
585.4 Chronic kidney disease, Stage I or II Genitourinary 0.994 0.907 – 1.09 0.897 509 7825 exclusion phecode
586 Other disorders of the kidney and ureters Genitourinary 1.03 0.998 – 1.07 0.0667 4118 24729 exclusion phecode
586.1 Anatomical abnormatilies of kidney and ureters Genitourinary 1.2 1.04 – 1.39 0.0113 210 2495 exclusion phecode
586.11 Small kidney Genitourinary 1.32 1.09 – 1.59 0.00476 127 1461 exclusion phecode
586.12 Vesicoureteral reflux Genitourinary 1.14 0.913 – 1.43 0.245 82 1045 exclusion phecode
586.2 Cyst of kidney, acquired Genitourinary 0.967 0.894 – 1.04 0.39 700 8907 exclusion phecode
586.3 Vascular disorders of kidney/hypertrophy Genitourinary 0.899 0.724 – 1.12 0.337 91 1309 exclusion phecode
586.4 Stricture/obstruction of ureter Genitourinary 1.03 0.97 – 1.1 0.316 1124 12124 exclusion phecode
587 Kidney replaced by transpant Genitourinary 1.06 0.958 – 1.17 0.262 447 5712 exclusion phecode
588 Disorders resulting from impaired renal function Genitourinary 1.03 0.93 – 1.14 0.598 419 6506 exclusion phecode
588.1 Renal osteodystrophy Genitourinary 0.951 0.799 – 1.13 0.568 146 2027 exclusion phecode
588.2 Secondary hyperparathyroidism (of renal origin) Genitourinary 1.07 0.954 – 1.2 0.25 314 5031 exclusion phecode
589 Abnormal results of function study of kidney Genitourinary 1.05 0.954 – 1.15 0.323 470 6861 exclusion phecode
590 Pyelonephritis Genitourinary 1.07 0.995 – 1.16 0.0672 705 10514 exclusion phecode
591 Urinary tract infection Genitourinary 1.01 0.978 – 1.04 0.607 5334 23321 exclusion phecode
592 Cystitis and urethritis Genitourinary 1 0.948 – 1.06 0.987 1465 17642 exclusion phecode
592.1 Cystitis Genitourinary 1 0.946 – 1.06 0.998 1382 17003 exclusion phecode
592.11 Acute cystitis Genitourinary 0.953 0.886 – 1.02 0.194 794 11922 exclusion phecode
592.12 Chronic cystitis Genitourinary 1.05 0.867 – 1.28 0.599 111 1680 exclusion phecode
592.13 Chronic interstitial cystitis Genitourinary 1.07 0.935 – 1.21 0.341 245 3200 exclusion phecode
592.2 Urethritis and urethral syndrome Genitourinary 1.03 0.836 – 1.26 0.813 98 1517 exclusion phecode
593 Hematuria Genitourinary 1.01 0.966 – 1.05 0.727 2439 22952 exclusion phecode
593.1 Gross hematuria Genitourinary 0.962 0.896 – 1.03 0.28 837 10187 exclusion phecode
593.2 Microscopic hematuria Genitourinary 1.01 0.915 – 1.11 0.906 475 7218 exclusion phecode
594 Urinary calculus Genitourinary 1.05 1.01 – 1.09 0.00717 3826 26385 exclusion phecode
594.1 Calculus of kidney Genitourinary 1.05 1.01 – 1.09 0.0066 3564 26268 exclusion phecode
594.2 Calculus of lower urinary tract Genitourinary 1.14 0.99 – 1.32 0.0675 213 2345 exclusion phecode
594.3 Calculus of ureter Genitourinary 1.1 1.01 – 1.19 0.02 687 9162 exclusion phecode
594.8 Renal colic Genitourinary 1.21 1.03 – 1.41 0.0189 168 2501 exclusion phecode
595 Hydronephrosis Genitourinary 1.07 1 – 1.15 0.0364 980 11386 exclusion phecode
596 Other disorders of bladder Genitourinary 1.06 1 – 1.11 0.0387 1635 18714 exclusion phecode
596.1 Bladder neck obstruction Genitourinary 1.16 1.01 – 1.32 0.0344 221 2582 exclusion phecode
596.5 Functional disorders of bladder Genitourinary 1.04 0.969 – 1.12 0.265 818 11416 exclusion phecode
597 Other disorders of urethra and urinary tract Genitourinary 1.08 1 – 1.17 0.044 710 8069 exclusion phecode
597.1 Urethral stricture (not specified as infectious) Genitourinary 1.1 0.988 – 1.21 0.083 407 4365 exclusion phecode
597.2 Urinary complications NEC Genitourinary 0.979 0.901 – 1.06 0.619 609 7007 exclusion phecode
597.8 Urethral hypermobility/ISD Genitourinary 1.29 1.06 – 1.58 0.0125 106 1232 exclusion phecode
598 Abnormal findings on examination of urine Genitourinary 1.03 0.812 – 1.3 0.831 73 878 exclusion phecode
598.4 Other cells and casts in urine Genitourinary 0.959 0.745 – 1.23 0.742 67 772 exclusion phecode
599 Other symptoms/disorders or the urinary system Genitourinary 1.02 0.99 – 1.04 0.238 7817 22603 exclusion phecode
599.1 Urinary obstruction Genitourinary 0.898 0.809 – 0.997 0.043 377 4734 exclusion phecode
599.2 Retention of urine Genitourinary 1 0.963 – 1.05 0.857 2749 20629 exclusion phecode
599.3 Dysuria Genitourinary 1 0.96 – 1.05 0.86 2189 20360 exclusion phecode
599.4 Urinary incontinence Genitourinary 1.06 1.02 – 1.1 0.00558 2860 19564 exclusion phecode
599.5 Frequency of urination and polyuria Genitourinary 1 0.96 – 1.04 0.995 2732 20915 exclusion phecode
599.6 Oliguria and anuria Genitourinary 0.983 0.868 – 1.11 0.78 277 4213 exclusion phecode
599.7 Urethral discharge Genitourinary 0.899 0.703 – 1.15 0.394 63 792 exclusion phecode
599.8 Other symptoms involving urinary system Genitourinary 1.01 0.97 – 1.05 0.648 3023 20280 exclusion phecode
599.9 Other abnormality of urination Genitourinary 1.02 0.963 – 1.07 0.56 1431 17911 exclusion phecode
600 Hyperplasia of prostate Genitourinary 0.978 0.928 – 1.03 0.402 2077 7404 exclusion phecode
601 Inflammatory diseases of prostate Genitourinary 0.943 0.857 – 1.04 0.234 463 6394 exclusion phecode
601.1 Prostatitis Genitourinary 0.859 0.742 – 0.994 0.0408 196 2990 exclusion phecode
601.11 Acute prostatitis Genitourinary 0.694 0.532 – 0.907 0.0075 55 776 exclusion phecode
601.12 Chronic prostatitis Genitourinary 0.96 0.695 – 1.32 0.803 39 615 exclusion phecode
601.3 Orchitis and epididymitis Genitourinary 1.03 0.881 – 1.2 0.709 168 2528 exclusion phecode
601.4 Balanoposthitis Genitourinary 1.03 0.805 – 1.31 0.833 67 859 exclusion phecode
601.8
Other inflammatory disorders of male genital
Other inflammatory disorders of male genital organs
 Genitourinary 0.949 0.746 – 1.21 0.673 73 1054 exclusion phecode
602 Other disorders of prostate Genitourinary 0.961 0.828 – 1.11 0.596 188 2256 exclusion phecode
602.3 Dysplasia of prostate Genitourinary 1.01 0.761 – 1.35 0.924 47 465 exclusion phecode
603 Other disorders of testis Genitourinary 0.906 0.791 – 1.04 0.149 235 3082 exclusion phecode
603.1 Hydrocele Genitourinary 0.986 0.83 – 1.17 0.867 145 2004 exclusion phecode
603.2 Spermatocele Genitourinary 0.797 0.643 – 0.989 0.0393 95 1117 exclusion phecode
604 Disorders of penis Genitourinary 0.988 0.888 – 1.1 0.828 369 4725 exclusion phecode
604.1 Redundant prepuce and phimosis/BXO Genitourinary 0.906 0.722 – 1.14 0.392 84 1067 exclusion phecode
604.3 Peyronie's disease Genitourinary 0.981 0.822 – 1.17 0.832 132 1446 exclusion phecode
605 Erectile dysfunction [ED] Genitourinary 0.983 0.935 – 1.03 0.506 1958 8826 exclusion phecode
608 Other disorders of male genital organs Genitourinary 0.983 0.915 – 1.06 0.63 840 9794 exclusion phecode
609 Male infertility and abnormal spermatozoa Genitourinary 0.935 0.822 – 1.06 0.303 254 3019 exclusion phecode
609.1 Infertility, male Genitourinary 0.941 0.81 – 1.09 0.429 189 2180 exclusion phecode
609.11 Azoospermia and oligospermia Genitourinary 0.97 0.755 – 1.25 0.815 69 717 exclusion phecode
609.2 Abnormal spermatozoa Genitourinary 0.968 0.784 – 1.2 0.762 91 1077 exclusion phecode
610 Benign mammary dysplasias Genitourinary 0.967 0.923 – 1.01 0.159 2133 12405 exclusion phecode
610.1 Cystic mastopathy Genitourinary 0.951 0.887 – 1.02 0.153 893 10422 exclusion phecode
610.2 Fibroadenosis of breast Genitourinary 1 0.687 – 1.47 0.986 33 450 exclusion phecode
610.4 Benign neoplasm of breast Genitourinary 0.965 0.916 – 1.02 0.173 1666 12304 exclusion phecode
610.8 Other specified benign mammary dysplasias Genitourinary 0.94 0.871 – 1.01 0.111 731 8956 exclusion phecode
611 Abnormal findings on mammogram or breast exam Genitourinary 0.935 0.899 – 0.972 0.000682 3310 13766 exclusion phecode
611.1 Abnormal mammogram Genitourinary 0.927 0.889 – 0.968 0.000538 2724 11942 exclusion phecode
611.11 Mammographic microcalcification Genitourinary 0.851 0.782 – 0.926 0.000185 586 7450 exclusion phecode
611.3 Lump or mass in breast Genitourinary 0.94 0.895 – 0.987 0.0129 1888 13706 exclusion phecode
612
Breast conditions, congenital or relating to
Breast conditions, congenital or relating to hormones
 Genitourinary 0.904 0.83 – 0.986 0.0228 565 7673 exclusion phecode
612.1 Galactorrhea Genitourinary 1.21 0.953 – 1.54 0.117 71 1067 exclusion phecode
612.2 Hypertrophy of breast (Gynecomastia) Genitourinary 0.887 0.802 – 0.982 0.021 411 5831 exclusion phecode
612.3 Congenital anomalies of breast Genitourinary 0.715 0.537 – 0.954 0.0226 49 628 exclusion phecode
613 Other nonmalignant breast conditions Genitourinary 0.959 0.916 – 1 0.0764 2151 15727 exclusion phecode
613.1 Inflammatory disease of breast Genitourinary 0.871 0.778 – 0.975 0.0161 317 4165 exclusion phecode
613.5 Mastodynia Genitourinary 0.96 0.893 – 1.03 0.274 800 11343 exclusion phecode
613.7 Other signs and symptoms in breast Genitourinary 0.946 0.858 – 1.04 0.264 441 6166 exclusion phecode
613.8 Other specified disorders of breast Genitourinary 0.958 0.878 – 1.05 0.339 555 6515 exclusion phecode
613.9 Breast disorder NOS Genitourinary 0.983 0.915 – 1.06 0.631 832 9815 exclusion phecode
614 Inflammatory diseases of female pelvic organs Genitourinary 1.01 0.967 – 1.06 0.558 1992 14301 exclusion phecode
614.1
Pelvic peritoneal adhesions, female
Pelvic peritoneal adhesions, female (postoperative) (postinfection)
 Genitourinary 0.947 0.823 – 1.09 0.451 207 2491 exclusion phecode
614.3 Pelvic inflammatory disease (PID) Genitourinary 1.04 0.912 – 1.18 0.572 254 3549 exclusion phecode
614.31 Acute inflammatory pelvic disease Genitourinary 1.03 0.792 – 1.34 0.822 57 718 exclusion phecode
614.32 Chronic inflammatory pelvic disease Genitourinary 1.02 0.838 – 1.24 0.854 111 1340 exclusion phecode
614.33 Pelvic inflammatory disease, NOS Genitourinary 1.07 0.892 – 1.29 0.45 124 1814 exclusion phecode
614.4 Inflammatory diseases of uterus, except cervix Genitourinary 1.14 0.938 – 1.39 0.185 105 1257 exclusion phecode
614.5
Inflammatory disease of cervix, vagina, and
Inflammatory disease of cervix, vagina, and vulva
 Genitourinary 1.01 0.961 – 1.07 0.666 1662 14240 exclusion phecode
614.51 Cervicitis and endocervicitis Genitourinary 1.02 0.859 – 1.2 0.852 145 1981 exclusion phecode
614.52 Vaginitis and vulvovaginitis Genitourinary 1.02 0.967 – 1.08 0.444 1396 13820 exclusion phecode
614.53 Cyst or abscess of Bartholin's gland Genitourinary 1.15 0.891 – 1.48 0.286 64 960 exclusion phecode
614.54 Abscess or ulceration of vulva Genitourinary 0.947 0.786 – 1.14 0.563 118 1638 exclusion phecode
615 Endometriosis Genitourinary 1.03 0.958 – 1.1 0.466 923 10685 exclusion phecode
618 Genital prolapse Genitourinary 1.03 0.967 – 1.09 0.39 1254 12186 exclusion phecode
618.1 Prolapse of vaginal walls Genitourinary 1.03 0.965 – 1.11 0.344 904 9001 exclusion phecode
618.2 Uterine/Uterovaginal prolapse Genitourinary 0.938 0.839 – 1.05 0.257 345 3609 exclusion phecode
618.5 Prolapse of vaginal vault after hysterectomy Genitourinary 1.17 1.02 – 1.34 0.0226 236 2103 exclusion phecode
618.6 Vaginal enterocele, congenital or acquired Genitourinary 1.19 1.04 – 1.36 0.0106 241 2926 exclusion phecode
619 Noninflammatory female genital disorders Genitourinary 0.963 0.927 – 1 0.053 3398 13552 exclusion phecode
619.1
Noninflammatory disorders of ovary, fallopian
Noninflammatory disorders of ovary, fallopian tube, and broad ligament
 Genitourinary 0.962 0.893 – 1.04 0.318 761 8969 exclusion phecode
619.2 Disorders of uterus, NEC Genitourinary 1.03 0.925 – 1.15 0.586 351 4287 exclusion phecode
619.3 Noninflammatory disorders of cervix Genitourinary 0.965 0.854 – 1.09 0.564 283 3573 exclusion phecode
619.4 Noninflammatory disorders of vagina Genitourinary 0.971 0.919 – 1.03 0.303 1419 13353 exclusion phecode
619.5 Noninflammatory disorders of vulva and perineum Genitourinary 0.985 0.907 – 1.07 0.714 621 8378 exclusion phecode
620 Dysplasia of female genital organs Genitourinary 1.01 0.878 – 1.15 0.936 220 2761 exclusion phecode
620.1 Dysplasia of cervix Genitourinary 0.911 0.747 – 1.11 0.36 101 1259 exclusion phecode
621 Endometrial hyperplasia Genitourinary 0.936 0.819 – 1.07 0.337 227 3030 exclusion phecode
622 Polyp of female genital organs Genitourinary 0.925 0.86 – 0.995 0.0372 780 9897 exclusion phecode
622.1 Polyp of corpus uteri Genitourinary 0.919 0.846 – 0.999 0.0466 609 7794 exclusion phecode
622.2 Mucous polyp of cervix Genitourinary 0.871 0.761 – 0.996 0.0436 222 3027 exclusion phecode
623 Hypertrophy of female genital organs Genitourinary 0.945 0.857 – 1.04 0.262 436 5685 exclusion phecode
624 Symptoms involving female genital tract Genitourinary 0.973 0.903 – 1.05 0.479 758 9455 exclusion phecode
624.1 Dystrophy of female genital tract Genitourinary 0.861 0.71 – 1.04 0.127 109 1518 exclusion phecode
624.2 Atrophy of female genital tract Genitourinary 1.11 0.785 – 1.57 0.551 35 436 exclusion phecode
624.9 stress incontinence, female Genitourinary 1.02 0.96 – 1.09 0.468 1012 11239 exclusion phecode
625
Pain and other symptoms associated with female
Pain and other symptoms associated with female genital organs
 Genitourinary 0.99 0.952 – 1.03 0.614 3169 12897 exclusion phecode
625.1 Dyspareunia Genitourinary 1.03 0.955 – 1.11 0.436 723 9338 exclusion phecode
626
Disorders of menstruation and other abnormal
Disorders of menstruation and other abnormal bleeding from female genital tract
 Genitourinary 0.95 0.913 – 0.988 0.01 3481 11860 exclusion phecode
626.1 Irregular menstrual cycle/bleeding Genitourinary 0.937 0.895 – 0.98 0.00478 2401 11131 exclusion phecode
626.11 Absent or infrequent menstruation Genitourinary 0.903 0.829 – 0.984 0.0197 589 6810 exclusion phecode
626.12 Excessive or frequent menstruation Genitourinary 0.98 0.92 – 1.04 0.537 1119 9297 exclusion phecode
626.13 Irregular menstrual cycle Genitourinary 0.955 0.894 – 1.02 0.168 1007 9497 exclusion phecode
626.14 Irregular menstrual bleeding Genitourinary 0.96 0.877 – 1.05 0.38 512 7064 exclusion phecode
626.15 Infertility, female, associated with anovulation Genitourinary 0.897 0.784 – 1.03 0.117 235 3083 exclusion phecode
626.2 Dysmenorrhea Genitourinary 0.99 0.92 – 1.07 0.797 793 7802 exclusion phecode
626.4 Premenstrual tension syndromes Genitourinary 0.883 0.753 – 1.04 0.129 158 2602 exclusion phecode
626.8 Infertility, female Genitourinary 0.903 0.825 – 0.988 0.0259 534 5438 exclusion phecode
627 Menopausal and postmenopausal disorders Genitourinary 0.954 0.912 – 0.999 0.0464 2307 10932 exclusion phecode
627.1 Postmenopausal bleeding Genitourinary 0.909 0.83 – 0.997 0.0425 504 7446 exclusion phecode
627.2 Symptomatic menopause Genitourinary 0.959 0.907 – 1.01 0.138 1482 10243 exclusion phecode
627.21 Symptomatic artificial menopause Genitourinary 0.828 0.663 – 1.03 0.0941 83 1145 exclusion phecode
627.22
Need for Hormone replacement therapy
Need for Hormone replacement therapy (postmenopausal)
 Genitourinary 0.934 0.794 – 1.1 0.412 162 2500 exclusion phecode
627.3 Postmenopausal atrophic vaginitis Genitourinary 0.965 0.88 – 1.06 0.454 492 6825 exclusion phecode
627.4 Premenopausal menorrhagia Genitourinary 1.03 0.889 – 1.2 0.658 180 2713 exclusion phecode
627.5 Premature menopause and other ovarian failure Genitourinary 0.786 0.676 – 0.914 0.00181 179 2358 exclusion phecode
628 Ovarian cyst Genitourinary 0.975 0.915 – 1.04 0.427 1078 10602 exclusion phecode
634 Miscarriage; stillbirth Pregnancy Complications 0.936 0.856 – 1.02 0.146 531 5934 exclusion phecode
634.1 Missed abortion/Hydatidiform mole Pregnancy Complications 0.873 0.744 – 1.02 0.0945 172 2032 exclusion phecode
634.3 Ectopic pregnancy Pregnancy Complications 0.943 0.751 – 1.19 0.616 84 883 exclusion phecode
635
Hemorrhage during pregnancy; childbirth and
Hemorrhage during pregnancy; childbirth and postpartum
 Pregnancy Complications 0.897 0.809 – 0.993 0.0364 408 4121 exclusion phecode
635.2
Antepartum hemorrhage, abruptio placentae, and
Antepartum hemorrhage, abruptio placentae, and placenta previa
 Pregnancy Complications 0.872 0.767 – 0.991 0.0357 262 2799 exclusion phecode
635.3 Placenta previa and abruptio placenta Pregnancy Complications 0.92 0.799 – 1.06 0.243 218 2265 exclusion phecode
636
Early or threatened labor; hemorrhage in early
Early or threatened labor; hemorrhage in early pregnancy
 Pregnancy Complications 0.953 0.882 – 1.03 0.225 723 5949 exclusion phecode
636.1 Threatened premature labor Pregnancy Complications 0.937 0.823 – 1.07 0.32 249 2948 exclusion phecode
636.2 Early onset of delivery Pregnancy Complications 0.981 0.849 – 1.13 0.789 194 2194 exclusion phecode
636.3 Hemorrhage in early pregnancy Pregnancy Complications 0.944 0.835 – 1.07 0.355 276 3360 exclusion phecode
636.8 Cervical incompetence Pregnancy Complications 1.12 0.835 – 1.51 0.444 50 597 exclusion phecode
637
Short gestation; low birth weight; and fetal
Short gestation; low birth weight; and fetal growth retardation
 Pregnancy Complications 1.2 0.875 – 1.63 0.262 39 627 exclusion phecode
642
Hypertension complicating pregnancy
Hypertension complicating pregnancy, childbirth, and the puerperium
 Pregnancy Complications 1.05 0.946 – 1.17 0.355 371 4382 exclusion phecode
642.1 Preeclampsia and eclampsia Pregnancy Complications 1.01 0.874 – 1.17 0.883 191 2298 exclusion phecode
643 Excessive vomiting in pregnancy Pregnancy Complications 1.03 0.877 – 1.21 0.723 164 1955 exclusion phecode
643.1 Hyperemesis gravidarum Pregnancy Complications 1.08 0.856 – 1.37 0.505 74 907 exclusion phecode
644 Anemia during pregnancy Pregnancy Complications 1.01 0.854 – 1.19 0.943 160 1747 exclusion phecode
646 Other complications of pregnancy NEC Pregnancy Complications 1.02 0.933 – 1.11 0.692 590 5080 exclusion phecode
647
Infectious and parasitic complications
Infectious and parasitic complications affecting pregnancy
 Pregnancy Complications 1.01 0.854 – 1.2 0.88 147 1581 exclusion phecode
647.1
Infections of genitourinary tract during
Infections of genitourinary tract during pregnancy
 Pregnancy Complications 1.17 0.984 – 1.38 0.0759 152 1751 exclusion phecode
647.3 Major puerperal infection Pregnancy Complications 0.879 0.655 – 1.18 0.392 51 514 exclusion phecode
649
Other conditions or status of the mother
Other conditions or status of the mother complicating pregnancy, childbirth, or the puerperium
 Pregnancy Complications 1.01 0.944 – 1.09 0.693 881 6088 exclusion phecode
649.1
Diabetes or abnormal glucose tolerance
Diabetes or abnormal glucose tolerance complicating pregnancy
 Pregnancy Complications 1.06 0.952 – 1.18 0.292 383 4086 exclusion phecode
653
Problems associated with amniotic cavity and
Problems associated with amniotic cavity and membranes
 Pregnancy Complications 1.03 0.927 – 1.14 0.622 407 4198 exclusion phecode
654.1
Abnormality of organs and soft tissues of
Abnormality of organs and soft tissues of pelvis complicating pregnancy, childbirth, or the puerperium
 Pregnancy Complications 1.08 0.911 – 1.28 0.383 149 1574 exclusion phecode
654.2 Rhesus isoimmunization in pregnancy Pregnancy Complications 1.06 0.889 – 1.25 0.539 140 1540 exclusion phecode
655
Known or suspected fetal abnormality affecting
Known or suspected fetal abnormality affecting management of mother
 Pregnancy Complications 0.992 0.93 – 1.06 0.812 1096 7473 exclusion phecode
655.1 Abnormality in fetal heart rate or rhythm Pregnancy Complications 0.93 0.843 – 1.03 0.143 447 4317 exclusion phecode
656 Other perinatal conditions of fetus or newborn Pregnancy Complications 1.01 0.929 – 1.1 0.798 616 5316 exclusion phecode
656.2 Respiratory conditions of fetus and newborn Pregnancy Complications 1.09 0.721 – 1.64 0.687 20 442 exclusion phecode
669 Complications of labor and delivery NEC Pregnancy Complications 0.983 0.905 – 1.07 0.686 630 5203 exclusion phecode
671
Venous/cerebrovascular complications embolism
Venous/cerebrovascular complications embolism in pregnancy and the puerperium
 Pregnancy Complications 1.03 0.86 – 1.22 0.781 141 1761 exclusion phecode
674 Other complications of the puerperium NEC Pregnancy Complications 1.02 0.835 – 1.24 0.863 106 1238 exclusion phecode
676
Other disorders of the breast associated with
Other disorders of the breast associated with childbirth and disorders of lactation
 Pregnancy Complications 0.889 0.741 – 1.07 0.202 127 1409 exclusion phecode
681 Superficial cellulitis and abscess Dermatologic 1 0.963 – 1.04 0.998 3039 27523 exclusion phecode
681.1 Cellulitis and abscess of fingers/toes Dermatologic 0.971 0.885 – 1.07 0.54 471 7931 exclusion phecode
681.2 Cellulitis and abscess of face/neck Dermatologic 0.946 0.861 – 1.04 0.243 467 6938 exclusion phecode
681.3 Cellulitis and abscess of arm/hand Dermatologic 0.984 0.919 – 1.05 0.652 869 13958 exclusion phecode
681.5 Cellulitis and abscess of leg, except foot Dermatologic 0.965 0.903 – 1.03 0.299 934 14615 exclusion phecode
681.6 Cellulitis and abscess of foot, toe Dermatologic 1.02 0.951 – 1.1 0.521 739 11711 exclusion phecode
681.7 Cellulitis and abscess of trunk Dermatologic 1.06 0.983 – 1.15 0.126 714 10877 exclusion phecode
686
Other local infections of skin and subcutaneous
Other local infections of skin and subcutaneous tissue
 Dermatologic 1.02 0.961 – 1.09 0.466 1037 15172 exclusion phecode
686.1 Carbuncle and furuncle Dermatologic 0.792 0.695 – 0.903 0.000485 240 3915 exclusion phecode
686.2 Impetigo Dermatologic 1.02 0.879 – 1.18 0.82 189 2934 exclusion phecode
686.3 Pilonidal cyst Dermatologic 0.839 0.678 – 1.04 0.108 89 1152 exclusion phecode
686.4 Pyogenic granuloma Dermatologic 1.05 0.837 – 1.32 0.663 77 1117 exclusion phecode
686.5 Pyoderma Dermatologic 1.58 1.09 – 2.28 0.0152 33 451 exclusion phecode
687 Symptoms affecting skin Dermatologic 0.955 0.886 – 1.03 0.232 736 11828 exclusion phecode
687.1 Rash and other nonspecific skin eruption Dermatologic 0.949 0.914 – 0.985 0.00553 3220 25645 exclusion phecode
687.3 Changes in skin texture Dermatologic 0.879 0.753 – 1.03 0.105 162 2893 exclusion phecode
687.4 Disturbance of skin sensation Dermatologic 0.999 0.961 – 1.04 0.96 2921 25275 exclusion phecode
689 Disorder of skin and subcutaneous tissue NOS Dermatologic 0.939 0.91 – 0.968 7.41e-05 4824 26709 exclusion phecode
690 Erythematosquamous dermatosis Dermatologic 0.934 0.895 – 0.974 0.00157 2447 22174 exclusion phecode
690.1 Seborrheic dermatitis Dermatologic 0.933 0.894 – 0.974 0.0015 2443 22151 exclusion phecode
691 Congenital anomalies of skin Dermatologic 0.924 0.814 – 1.05 0.218 253 3824 exclusion phecode
691.3 Congenital pigmentary anomalies of skin Dermatologic 0.661 0.46 – 0.949 0.0248 31 461 exclusion phecode
694 Dyschromia and Vitiligo Dermatologic 0.929 0.87 – 0.993 0.0314 965 12673 exclusion phecode
694.1 Vitiligo Dermatologic 0.972 0.777 – 1.22 0.801 80 922 exclusion phecode
694.2 Other dyschromia Dermatologic 0.922 0.859 – 0.989 0.0233 867 11436 exclusion phecode
694.3 Vascular disorders of skin Dermatologic 1.4 0.98 – 1.99 0.0646 32 564 exclusion phecode
695 Erythematous conditions Dermatologic 0.96 0.915 – 1.01 0.0907 1922 21553 exclusion phecode
695.1 Toxic erythema Dermatologic 0.967 0.691 – 1.35 0.844 39 495 exclusion phecode
695.2 Bullous dermatoses Dermatologic 0.927 0.665 – 1.29 0.658 37 534 exclusion phecode
695.3 Rosacea Dermatologic 0.907 0.846 – 0.973 0.00628 846 12423 exclusion phecode
695.4 Lupus (localized and systemic) Dermatologic 1.02 0.915 – 1.14 0.728 363 4872 exclusion phecode
695.41 Cutaneous lupus erythematosus Dermatologic 0.912 0.768 – 1.08 0.298 139 1787 exclusion phecode
695.42 Systemic lupus erythematosus Dermatologic 1.05 0.943 – 1.18 0.349 344 4611 exclusion phecode
695.7 Prurigo and Lichen Dermatologic 1.01 0.89 – 1.14 0.897 261 4183 exclusion phecode
695.8 Other specified erythematous conditions Dermatologic 0.981 0.871 – 1.1 0.749 295 5602 exclusion phecode
695.81 Erythema nodosum Dermatologic 0.838 0.587 – 1.19 0.327 31 425 exclusion phecode
695.9 Unspecified erythematous condition Dermatologic 1.08 0.958 – 1.22 0.21 284 4692 exclusion phecode
696 Psoriasis and related disorders Dermatologic 0.968 0.895 – 1.05 0.407 697 9819 exclusion phecode
696.3 Pityriasis Dermatologic 0.98 0.732 – 1.31 0.895 54 685 exclusion phecode
696.4 Psoriasis Dermatologic 0.974 0.898 – 1.06 0.524 643 9126 exclusion phecode
696.41 Psoriasis vulgaris Dermatologic 0.964 0.886 – 1.05 0.392 588 8340 exclusion phecode
696.42 Psoriatic arthropathy Dermatologic 0.992 0.821 – 1.2 0.934 123 1941 exclusion phecode
697 Sarcoidosis Dermatologic 0.985 0.828 – 1.17 0.863 139 2306 exclusion phecode
698 Pruritus and related conditions Dermatologic 0.975 0.914 – 1.04 0.444 1000 15004 exclusion phecode
700 Corns and callosities Dermatologic 0.902 0.824 – 0.988 0.0264 514 7431 exclusion phecode
701
Other hypertrophic and atrophic conditions of
Other hypertrophic and atrophic conditions of skin
 Dermatologic 0.962 0.929 – 0.995 0.0251 3899 27182 exclusion phecode
701.1 Keratoderma, acquired Dermatologic 0.908 0.795 – 1.04 0.16 227 3777 exclusion phecode
701.2 Scar conditions and fibrosis of skin Dermatologic 0.973 0.918 – 1.03 0.341 1305 15231 exclusion phecode
701.3 Circumscribed scleroderma Dermatologic 0.885 0.789 – 0.994 0.039 318 3954 exclusion phecode
701.4 Keloid scar Dermatologic 1.02 0.908 – 1.14 0.769 324 4172 exclusion phecode
701.5 Abnormal granulation tissue Dermatologic 1.04 0.895 – 1.2 0.634 193 2849 exclusion phecode
702
Degenerative skin conditions and other
Degenerative skin conditions and other dermatoses
 Dermatologic 0.922 0.888 – 0.957 1.87e-05 3429 20886 exclusion phecode
702.1 Actinic keratosis Dermatologic 0.936 0.893 – 0.981 0.00617 2037 17882 exclusion phecode
702.2 Seborrheic keratosis Dermatologic 0.916 0.879 – 0.955 3.77e-05 2613 21468 exclusion phecode
702.4 Degenerative skin disorders Dermatologic 0.849 0.622 – 1.16 0.304 38 613 exclusion phecode
703 Diseases of nail, NOS Dermatologic 0.95 0.874 – 1.03 0.232 590 9935 exclusion phecode
703.1 Ingrowing nail Dermatologic 1.02 0.908 – 1.14 0.749 307 5909 exclusion phecode
704 Diseases of hair and hair follicles Dermatologic 0.938 0.89 – 0.989 0.0184 1498 20799 exclusion phecode
704.1 Alopecia Dermatologic 0.968 0.897 – 1.05 0.412 706 9931 exclusion phecode
704.11 Alopecia Areata Dermatologic 0.899 0.662 – 1.22 0.496 40 564 exclusion phecode
704.12 Telogen effluvium Dermatologic 0.935 0.631 – 1.39 0.739 23 480 exclusion phecode
704.2 Hirsutism Dermatologic 0.91 0.775 – 1.07 0.246 153 2202 exclusion phecode
704.8
Other specified diseases of hair and hair
Other specified diseases of hair and hair follicles
 Dermatologic 0.933 0.868 – 1 0.0591 795 11856 exclusion phecode
705 Disorders of sweat glands Dermatologic 0.9 0.798 – 1.02 0.0863 269 4382 exclusion phecode
705.1 Dyshidrosis Dermatologic 0.806 0.64 – 1.02 0.0676 72 1081 exclusion phecode
705.3 Hidradenitis Dermatologic 0.974 0.808 – 1.17 0.779 114 1825 exclusion phecode
705.8 Hyperhidrosis Dermatologic 0.933 0.844 – 1.03 0.173 423 7768 exclusion phecode
706 Diseases of sebaceous glands Dermatologic 0.928 0.893 – 0.965 0.000154 2953 28234 exclusion phecode
706.1 Acne Dermatologic 0.917 0.867 – 0.97 0.00238 1362 16562 exclusion phecode
706.2 Sebaceous cyst Dermatologic 0.933 0.882 – 0.987 0.0163 1330 18685 exclusion phecode
706.3 Seborrhea Dermatologic 0.73 0.477 – 1.12 0.149 17 408 exclusion phecode
706.8 Other specified diseases of sebaceous glands Dermatologic 0.942 0.871 – 1.02 0.131 684 10397 exclusion phecode
707 Chronic ulcer of skin Dermatologic 1.04 0.985 – 1.1 0.154 1306 17885 exclusion phecode
707.1 Decubitus ulcer Dermatologic 1.02 0.913 – 1.14 0.743 347 5319 exclusion phecode
707.2 Chronic ulcer of leg or foot Dermatologic 1.05 0.957 – 1.16 0.284 447 6465 exclusion phecode
707.3 Chronic ulcer of unspecified site Dermatologic 1.07 0.993 – 1.15 0.0759 747 10758 exclusion phecode
709 Diffuse diseases of connective tissue Dermatologic 0.989 0.914 – 1.07 0.776 670 10361 exclusion phecode
709.2 Sicca syndrome Dermatologic 1.04 0.906 – 1.19 0.603 228 3557 exclusion phecode
709.3 Systemic sclerosis Dermatologic 0.98 0.809 – 1.19 0.839 107 1574 exclusion phecode
709.5 Dermatomyositis Dermatologic 0.893 0.66 – 1.21 0.461 41 643 exclusion phecode
709.6
Other specified diffuse diseases of connective
Other specified diffuse diseases of connective tissue
 Dermatologic 1.17 0.852 – 1.61 0.33 39 672 exclusion phecode
709.7 Unspecified diffuse connective tissue disease Dermatologic 0.971 0.877 – 1.08 0.573 399 6533 exclusion phecode
710
Osteomyelitis, periostitis, and other
Osteomyelitis, periostitis, and other infections involving bone
 Musculoskeletal 1.11 1.02 – 1.2 0.013 644 8720 exclusion phecode
710.1 Osteomyelitis Musculoskeletal 1.11 1.02 – 1.2 0.0181 615 8373 exclusion phecode
710.11 Acute osteomyelitis Musculoskeletal 1.25 1.1 – 1.42 0.000504 272 4038 exclusion phecode
710.12 Chronic osteomyelitis Musculoskeletal 1.2 1.05 – 1.36 0.007 252 3626 exclusion phecode
710.19 Unspecified osteomyelitis Musculoskeletal 1.1 1.01 – 1.2 0.0276 590 7997 exclusion phecode
711 Arthropathy associated with infections Musculoskeletal 1.1 0.95 – 1.28 0.201 192 2991 exclusion phecode
711.1 Pyogenic arthritis Musculoskeletal 1.17 0.982 – 1.39 0.0797 136 2094 exclusion phecode
712 Infective connective tissue disorders Musculoskeletal 0.908 0.71 – 1.16 0.442 70 1277 exclusion phecode
713
Arthropathy associated with other disorders
Arthropathy associated with other disorders classified elsewhere
 Musculoskeletal 0.921 0.766 – 1.11 0.38 125 2108 exclusion phecode
713.5
Arthropathy associated with neurological
Arthropathy associated with neurological disorders
 Musculoskeletal 0.849 0.672 – 1.07 0.171 73 1191 exclusion phecode
714
Rheumatoid arthritis and other inflammatory
Rheumatoid arthritis and other inflammatory polyarthropathies
 Musculoskeletal 1.08 1.01 – 1.15 0.0208 1046 13305 exclusion phecode
714.1 Rheumatoid arthritis Musculoskeletal 1.09 1.01 – 1.17 0.0176 869 11062 exclusion phecode
714.2 Juvenile rheumatoid arthritis Musculoskeletal 0.726 0.54 – 0.976 0.0338 41 603 exclusion phecode
715 Other inflammatory spondylopathies Musculoskeletal 1.07 0.98 – 1.18 0.127 488 8689 exclusion phecode
715.1 Sacroiliitis NEC Musculoskeletal 1.21 1 – 1.46 0.0488 116 1936 exclusion phecode
715.2 Ankylosing spondylitis Musculoskeletal 0.925 0.767 – 1.12 0.418 117 1592 exclusion phecode
716 Other arthropathies Musculoskeletal 1.05 1.03 – 1.08 0.00019 7055 23284 exclusion phecode
716.1 Unspecified polyarthropathy or polyarthritis Musculoskeletal 1.13 0.897 – 1.42 0.299 76 1398 exclusion phecode
716.2 Unspecified monoarthritis Musculoskeletal 0.936 0.722 – 1.21 0.618 59 943 exclusion phecode
716.9 Arthropathy NOS Musculoskeletal 1.05 1.02 – 1.08 0.00032 7020 23274 exclusion phecode
717 Polymyalgia Rheumatica Musculoskeletal 0.969 0.814 – 1.15 0.719 136 1616 exclusion phecode
720 Spinal stenosis Musculoskeletal 1.07 1.02 – 1.12 0.00581 1846 20153 exclusion phecode
720.1 Spinal stenosis of lumbar region Musculoskeletal 1.06 1 – 1.12 0.0364 1315 16580 exclusion phecode
721 Spondylosis and allied disorders Musculoskeletal 1.03 0.986 – 1.07 0.183 2393 23209 exclusion phecode
721.1 Spondylosis without myelopathy Musculoskeletal 1.03 0.989 – 1.08 0.139 2202 22799 exclusion phecode
721.2 Spondylosis with myelopathy Musculoskeletal 1.05 0.944 – 1.16 0.383 397 6089 exclusion phecode
721.8 Other allied disorders of spine Musculoskeletal 0.87 0.713 – 1.06 0.171 100 1777 exclusion phecode
722 Intervertebral disc disorders Musculoskeletal 1.05 1.01 – 1.09 0.00975 2998 24866 exclusion phecode
722.1 Displacement of intervertebral disc Musculoskeletal 1.06 1.01 – 1.12 0.0221 1673 22588 exclusion phecode
722.3 Schmorl's nodes Musculoskeletal 0.923 0.691 – 1.23 0.589 48 905 exclusion phecode
722.6 Degeneration of intervertebral disc Musculoskeletal 1.06 1.01 – 1.11 0.0206 1800 21883 exclusion phecode
722.7 Intervertebral disc disorder with myelopathy Musculoskeletal 1.03 0.904 – 1.18 0.643 243 3650 exclusion phecode
722.8 Postlaminectomy syndrome Musculoskeletal 1.1 0.942 – 1.29 0.226 167 2800 exclusion phecode
722.9 Other and unspecified disc disorder Musculoskeletal 1.03 0.961 – 1.1 0.418 886 13701 exclusion phecode
723 Other disorders of cervical region Musculoskeletal 1.07 0.963 – 1.18 0.218 402 6862 exclusion phecode
723.1 Torticollis Musculoskeletal 0.912 0.756 – 1.1 0.332 115 1832 exclusion phecode
724 Other and unspecified disorders of back Musculoskeletal 1.03 0.986 – 1.09 0.167 1820 23197 exclusion phecode
724.1 Disorders of sacrum Musculoskeletal 1.07 0.999 – 1.14 0.0524 936 15873 exclusion phecode
724.2 Disorders of coccyx Musculoskeletal 0.99 0.843 – 1.16 0.901 159 3056 exclusion phecode
724.8 Other symptoms referable to back Musculoskeletal 0.971 0.877 – 1.07 0.565 398 6751 exclusion phecode
724.9 Other unspecified back disorders Musculoskeletal 1.04 0.967 – 1.13 0.267 696 10084 exclusion phecode
726 Peripheral enthesopathies and allied syndromes Musculoskeletal 0.964 0.934 – 0.995 0.0229 4804 22999 exclusion phecode
726.1 Enthesopathy Musculoskeletal 0.989 0.954 – 1.02 0.531 3629 22947 exclusion phecode
726.2 Synoviopathy Musculoskeletal 1.07 0.972 – 1.18 0.167 454 7359 exclusion phecode
726.3 Bursitis Musculoskeletal 0.988 0.918 – 1.06 0.749 793 12505 exclusion phecode
726.4 Calcaneal spur; Exostosis NOS Musculoskeletal 0.962 0.881 – 1.05 0.377 555 8586 exclusion phecode
727 Other disorders of synovium, tendon, and bursa Musculoskeletal 0.994 0.959 – 1.03 0.73 3630 22944 exclusion phecode
727.1 Synovitis and tenosynovitis Musculoskeletal 0.994 0.942 – 1.05 0.827 1450 19018 exclusion phecode
727.2 Bursitis disorders Musculoskeletal 0.921 0.794 – 1.07 0.276 183 3063 exclusion phecode
727.4 Ganglion and cyst of synovium, tendon, and bursa Musculoskeletal 0.946 0.874 – 1.02 0.164 682 10241 exclusion phecode
727.5 Rupture of synovium Musculoskeletal 0.908 0.787 – 1.05 0.183 205 3512 exclusion phecode
727.6 Rupture of tendon, nontraumatic Musculoskeletal 1.03 0.964 – 1.09 0.414 1092 16132 exclusion phecode
727.7 Contracture of tendon (sheath) Musculoskeletal 1.07 0.938 – 1.21 0.328 265 4518 exclusion phecode
727.8 Plica syndrome Musculoskeletal 1.03 0.841 – 1.26 0.772 99 1017 exclusion phecode
728 Disorders of muscle, ligament, and fascia Musculoskeletal 0.984 0.939 – 1.03 0.477 2053 22379 exclusion phecode
728.1 Muscular calcification and ossification Musculoskeletal 1.36 1 – 1.86 0.0493 40 625 exclusion phecode
728.2 Laxity of ligament or hypermobility syndrome Musculoskeletal 0.975 0.827 – 1.15 0.763 148 2282 exclusion phecode
728.7 Fasciitis Musculoskeletal 0.965 0.91 – 1.02 0.245 1188 17599 exclusion phecode
728.71
Contracture of palmar fascia [Dupuytren's
Contracture of palmar fascia [Dupuytren's disease]
 Musculoskeletal 1.05 0.91 – 1.21 0.521 209 2916 exclusion phecode
729 Other disorders of soft tissues Musculoskeletal 1.03 0.979 – 1.09 0.248 1567 20656 exclusion phecode
729.1 Rheumatism, unspecified and fibrositis Musculoskeletal 1.27 0.833 – 1.95 0.263 22 529 exclusion phecode
729.3 Panniculitis Musculoskeletal 0.807 0.59 – 1.1 0.178 42 874 exclusion phecode
729.7 Nontraumatic compartment syndrome Musculoskeletal 0.97 0.709 – 1.33 0.848 36 492 exclusion phecode
731
Osteitis deformans and osteopathies associated
Osteitis deformans and osteopathies associated with other disorders classified elsewhere
 Musculoskeletal 0.867 0.705 – 1.07 0.174 96 1350 exclusion phecode
732 Osteochondropathies Musculoskeletal 0.903 0.791 – 1.03 0.127 231 2765 exclusion phecode
732.1 Juvenile osteochondrosis Musculoskeletal 0.909 0.757 – 1.09 0.304 115 1468 exclusion phecode
732.7 Osteochondritis dissecans Musculoskeletal 0.942 0.736 – 1.2 0.633 61 682 exclusion phecode
733 Other disorders of bone and cartilage Musculoskeletal 0.942 0.9 – 0.986 0.00951 2234 19146 exclusion phecode
733.2 Cyst of bone Musculoskeletal 0.857 0.702 – 1.05 0.13 99 1364 exclusion phecode
733.4 Aseptic necrosis of bone Musculoskeletal 0.947 0.841 – 1.07 0.37 300 3611 exclusion phecode
733.6 Costochondritis Musculoskeletal 0.903 0.762 – 1.07 0.237 134 2626 exclusion phecode
733.8 Malunion and nonunion of fracture Musculoskeletal 1.08 0.982 – 1.19 0.111 479 5946 exclusion phecode
733.9 Chondromalacia Musculoskeletal 1.21 0.934 – 1.58 0.147 59 760 exclusion phecode
735 Acquired foot deformities Musculoskeletal 0.985 0.935 – 1.04 0.57 1550 20497 exclusion phecode
735.1 Flat foot Musculoskeletal 0.868 0.764 – 0.987 0.0308 257 4128 exclusion phecode
735.2 Acquired toe deformities Musculoskeletal 0.965 0.883 – 1.05 0.435 554 7994 exclusion phecode
735.21 Hammer toe (acquired) Musculoskeletal 0.926 0.826 – 1.04 0.188 326 4940 exclusion phecode
735.23 Hallux rigidus Musculoskeletal 0.97 0.832 – 1.13 0.694 181 2633 exclusion phecode
735.3 Hallux valgus (Bunion) Musculoskeletal 0.992 0.916 – 1.07 0.838 669 9823 exclusion phecode
736 Other acquired deformities of limbs Musculoskeletal 1.03 0.973 – 1.09 0.31 1336 18464 exclusion phecode
736.1 Acquired deformities of forearm Musculoskeletal 1.14 0.871 – 1.49 0.339 52 722 exclusion phecode
736.2 Acquired deformities of finger Musculoskeletal 1.01 0.834 – 1.23 0.9 107 1506 exclusion phecode
736.3 Acquired deformities of hip Musculoskeletal 1.31 0.945 – 1.8 0.106 38 456 exclusion phecode
736.4 Genu valgum or varum (acquired) Musculoskeletal 0.865 0.742 – 1.01 0.0632 167 2266 exclusion phecode
736.5 Acquired deformities of knee Musculoskeletal 0.818 0.68 – 0.984 0.0335 116 1701 exclusion phecode
736.6 Unequal leg length (acquired) Musculoskeletal 1.09 0.926 – 1.28 0.305 159 2364 exclusion phecode
737 Curvature of spine Musculoskeletal 0.966 0.9 – 1.04 0.346 827 11046 exclusion phecode
737.1 Kyphosis (acquired) Musculoskeletal 0.999 0.875 – 1.14 0.987 236 3348 exclusion phecode
737.2 Lordosis (acquired) Musculoskeletal 0.997 0.732 – 1.36 0.984 42 497 exclusion phecode
737.3 Kyphoscoliosis and scoliosis Musculoskeletal 0.956 0.881 – 1.04 0.278 646 8567 exclusion phecode
738 Other acquired musculoskeletal deformity Musculoskeletal 0.962 0.91 – 1.02 0.182 1359 16881 exclusion phecode
738.4 Acquired spondylolisthesis Musculoskeletal 1.02 0.936 – 1.12 0.597 517 7122 exclusion phecode
739 Contracture of joint Musculoskeletal 0.972 0.867 – 1.09 0.624 327 4304 exclusion phecode
740 Osteoarthrosis Musculoskeletal 1.05 1.02 – 1.08 0.000548 8512 22851 exclusion phecode
740.1 Osteoarthritis; localized Musculoskeletal 1 0.964 – 1.04 0.936 3280 20372 exclusion phecode
740.11 Osteoarthrosis, localized, primary Musculoskeletal 0.994 0.955 – 1.04 0.785 2839 19316 exclusion phecode
740.12 Osteoarthrosis, localized, secondary Musculoskeletal 1.02 0.917 – 1.14 0.69 361 5297 exclusion phecode
740.2 Osteoarthrosis, generalized Musculoskeletal 1 0.924 – 1.09 0.94 614 8934 exclusion phecode
740.3
Osteoarthrosis involving more than one site
Osteoarthrosis involving more than one site, but not specified as generalized
 Musculoskeletal 1.06 0.896 – 1.25 0.501 146 2674 exclusion phecode
740.9 Osteoarthrosis NOS Musculoskeletal 1.05 1.02 – 1.08 0.000655 8114 22733 exclusion phecode
741 Symptoms and disorders of the joints Musculoskeletal 1.01 0.974 – 1.04 0.731 4378 25946 exclusion phecode
741.1 Ankylosis of joint Musculoskeletal 0.957 0.803 – 1.14 0.624 139 1765 exclusion phecode
741.2 Stiffness of joint Musculoskeletal 1.07 0.985 – 1.16 0.114 654 8967 exclusion phecode
741.3 Difficulty in walking Musculoskeletal 1.01 0.951 – 1.07 0.735 1134 16274 exclusion phecode
741.4 Joint effusions Musculoskeletal 0.988 0.93 – 1.05 0.681 1170 17473 exclusion phecode
741.5 Hemarthrosis Musculoskeletal 1.02 0.739 – 1.4 0.918 35 666 exclusion phecode
741.6 Villonodular synovitis Musculoskeletal 1.25 0.878 – 1.77 0.217 33 482 exclusion phecode
742 Derangement of joint, non-traumatic Musculoskeletal 1.01 0.97 – 1.06 0.555 2231 24510 exclusion phecode
742.1 Loose body in joint Musculoskeletal 0.995 0.808 – 1.23 0.963 90 1171 exclusion phecode
742.2
Pathological, developmental or recurrent
Pathological, developmental or recurrent dislocation
 Musculoskeletal 0.933 0.799 – 1.09 0.377 177 2234 exclusion phecode
742.8 Articular cartilage disorder Musculoskeletal 0.902 0.759 – 1.07 0.243 143 1796 exclusion phecode
742.9 Other derangement of joint Musculoskeletal 1.02 0.972 – 1.07 0.448 2069 23979 exclusion phecode
743
Osteoporosis, osteopenia and pathological
Osteoporosis, osteopenia and pathological fracture
 Musculoskeletal 0.978 0.948 – 1.01 0.182 4872 26255 exclusion phecode
743.1 Osteoporosis Musculoskeletal 1.01 0.961 – 1.06 0.666 1924 13563 exclusion phecode
743.11 Osteoporosis NOS Musculoskeletal 1.01 0.961 – 1.06 0.669 1897 13425 exclusion phecode
743.12 Senile osteoporosis Musculoskeletal 1.02 0.909 – 1.14 0.762 344 4146 exclusion phecode
743.13 Other specified osteoporosis Musculoskeletal 0.949 0.794 – 1.13 0.561 132 2177 exclusion phecode
743.2 Pathologic fracture Musculoskeletal 0.981 0.898 – 1.07 0.676 537 7306 exclusion phecode
743.21 Pathologic fracture of vertebrae Musculoskeletal 0.966 0.842 – 1.11 0.616 227 3199 exclusion phecode
743.22 Pathologic fracture of femur Musculoskeletal 0.898 0.694 – 1.16 0.41 68 1011 exclusion phecode
743.4 Stress fracture Musculoskeletal 0.914 0.788 – 1.06 0.235 192 2828 exclusion phecode
743.9
Osteopenia or other disorder of bone and
Osteopenia or other disorder of bone and cartilage
 Musculoskeletal 0.957 0.923 – 0.993 0.0189 3522 24956 exclusion phecode
745 Pain in joint Musculoskeletal 0.985 0.962 – 1.01 0.221 10927 20720 exclusion phecode
747 Cardiac and circulatory congenital anomalies Congenital Anomalies 1.01 0.952 – 1.07 0.71 1182 15107 exclusion phecode
747.1 Cardiac congenital anomalies Congenital Anomalies 1.06 0.985 – 1.13 0.128 892 11934 exclusion phecode
747.11 Cardiac shunt/ heart septal defect Congenital Anomalies 1.05 0.939 – 1.17 0.408 345 4502 exclusion phecode
747.12 Valvular heart disease/ heart chambers Congenital Anomalies 1.05 0.946 – 1.17 0.345 364 5026 exclusion phecode
747.13 Congenital anomalies of great vessels Congenital Anomalies 1.13 0.974 – 1.3 0.11 201 2812 exclusion phecode
747.2
Congenital anomalies of peripheral vascular
Congenital anomalies of peripheral vascular system
 Congenital Anomalies 0.961 0.853 – 1.08 0.52 303 3459 exclusion phecode
748 Anomalies of respiratory system, congenital Congenital Anomalies 1.13 0.856 – 1.5 0.385 55 722 exclusion phecode
749 Congenital anomalies of face and neck Congenital Anomalies 1.03 0.917 – 1.15 0.646 343 3980 exclusion phecode
749.1 Cleft palate Congenital Anomalies 1.12 0.876 – 1.43 0.373 71 772 exclusion phecode
749.2 Congenital anomalies of skull and face bones Congenital Anomalies 0.85 0.656 – 1.1 0.221 61 785 exclusion phecode
750 Digestive congenital anomalies Congenital Anomalies 0.97 0.881 – 1.07 0.536 453 6029 exclusion phecode
750.1 Upper gastrointestinal congenital anomalies Congenital Anomalies 0.885 0.76 – 1.03 0.116 183 2477 exclusion phecode
750.11 Esophageal atresia/tracheoesophageal fistula Congenital Anomalies 0.79 0.608 – 1.03 0.0774 59 810 exclusion phecode
750.13 Congenital anomalies of mouth/tongue Congenital Anomalies 0.864 0.649 – 1.15 0.314 47 710 exclusion phecode
750.14 Congenital anomalies of esophagus Congenital Anomalies 0.835 0.654 – 1.07 0.146 68 914 exclusion phecode
750.15 Congenital anomalies of stomach Congenital Anomalies 1.14 0.796 – 1.64 0.468 34 383 exclusion phecode
750.2 Lower gastrointestinal congenital anomalies Congenital Anomalies 1.04 0.92 – 1.18 0.531 274 3543 exclusion phecode
750.21 Congenital anomalies of intestine Congenital Anomalies 0.969 0.827 – 1.14 0.7 162 2084 exclusion phecode
750.22
Congenital anomaly of gallbladder, bile ducts
Congenital anomaly of gallbladder, bile ducts, liver, pancreas
 Congenital Anomalies 1.13 0.933 – 1.37 0.212 113 1492 exclusion phecode
751 Genitourinary congenital anomalies Congenital Anomalies 1.01 0.952 – 1.07 0.709 1162 13694 exclusion phecode
751.1 Congenital anomalies of genital organs Congenital Anomalies 1.02 0.918 – 1.14 0.664 348 4133 exclusion phecode
751.11 Congenital anomalies of female genital organs Congenital Anomalies 1.01 0.882 – 1.16 0.881 228 2765 exclusion phecode
751.12 Congenital anomalies of male genital organs Congenital Anomalies 0.999 0.809 – 1.23 0.993 94 1089 exclusion phecode
751.2 Congenital anomalies of urinary system Congenital Anomalies 1.01 0.938 – 1.09 0.779 764 9239 exclusion phecode
751.21 Cystic kidney disease Congenital Anomalies 0.947 0.865 – 1.04 0.231 521 6460 exclusion phecode
751.22 Other specified congenital anomalies of kidney Congenital Anomalies 1.09 0.936 – 1.28 0.257 175 2000 exclusion phecode
751.3 Obstructive genitourinary defect Congenital Anomalies 1.09 0.911 – 1.31 0.339 132 1302 exclusion phecode
752 Nervous system congenital anomalies Congenital Anomalies 0.989 0.909 – 1.08 0.805 594 7660 exclusion phecode
752.1 Neural tube defects Congenital Anomalies 0.982 0.895 – 1.08 0.709 488 6154 exclusion phecode
752.11 Spina bifida Congenital Anomalies 0.928 0.759 – 1.13 0.465 108 1286 exclusion phecode
752.2
Other specified congenital anomalies of nervous
Other specified congenital anomalies of nervous system
 Congenital Anomalies 1.01 0.844 – 1.22 0.875 124 1660 exclusion phecode
753 Congenital anomalies of the eye Congenital Anomalies 0.996 0.821 – 1.21 0.967 110 1360 exclusion phecode
753.1 Congenital cataract and lens anomalies Congenital Anomalies 1.16 0.807 – 1.66 0.428 26 400 exclusion phecode
753.2 Congenital anomalies of posterior segment of eye Congenital Anomalies 0.702 0.493 – 0.999 0.0493 33 367 exclusion phecode
754 Congenital musculoskeletal deformities of spine Congenital Anomalies 1.03 0.943 – 1.12 0.549 596 8056 exclusion phecode
754.1 Lumbosacral spondylolysis, congenital Congenital Anomalies 1.12 0.866 – 1.45 0.384 56 915 exclusion phecode
754.2 Spondylolisthesis, congenital Congenital Anomalies 0.988 0.874 – 1.12 0.853 287 3659 exclusion phecode
755 Congenital anomalies of limbs Congenital Anomalies 1.02 0.924 – 1.13 0.672 414 5254 exclusion phecode
755.1 Congenital deformities of feet Congenital Anomalies 1 0.862 – 1.16 0.987 193 2462 exclusion phecode
755.4
Congenital anomalies of upper limb, including
Congenital anomalies of upper limb, including shoulder girdle
 Congenital Anomalies 1.01 0.729 – 1.4 0.946 36 526 exclusion phecode
755.6
Other congenital anomalies of lower limb
Other congenital anomalies of lower limb, including pelvic girdle
 Congenital Anomalies 1.03 0.894 – 1.19 0.675 198 2374 exclusion phecode
755.61 Congenital hip dysplasia and deformity Congenital Anomalies 1 0.834 – 1.2 0.998 123 1376 exclusion phecode
756 Other congenital musculoskeletal anomalies Congenital Anomalies 0.993 0.92 – 1.07 0.866 724 9440 exclusion phecode
756.1 Congenital anomalies of abdominal wall; diaphram Congenital Anomalies 0.93 0.685 – 1.26 0.641 43 490 exclusion phecode
756.2
Pectus and other congenital anomalies of
Pectus and other congenital anomalies of ribs/sternum
 Congenital Anomalies 1.12 0.854 – 1.46 0.422 53 559 exclusion phecode
756.3
Congenital anomalies of muscle, tendon, fascia
Congenital anomalies of muscle, tendon, fascia, and connective tissue
 Congenital Anomalies 0.928 0.797 – 1.08 0.336 171 2396 exclusion phecode
756.5 Congenital osteodystrophies Congenital Anomalies 0.96 0.877 – 1.05 0.384 505 6769 exclusion phecode
757 Congenital anomalies of the integument Congenital Anomalies 0.998 0.87 – 1.14 0.972 235 2629 exclusion phecode
758 Chromosomal anomalies and genetic disorders Congenital Anomalies 0.844 0.697 – 1.02 0.0812 106 1325 exclusion phecode
758.1 Chromosomal anomalies Congenital Anomalies 0.857 0.687 – 1.07 0.171 78 952 exclusion phecode
759 Other and unspecified congenital anomalies Congenital Anomalies 1 0.894 – 1.12 0.972 324 3962 exclusion phecode
759.1 Anomalies of endocrine glands, congenital Congenital Anomalies 1.02 0.764 – 1.37 0.871 48 504 exclusion phecode
760 Back pain Symptoms 1.04 1.02 – 1.07 0.000976 8063 23565 exclusion phecode
761 Cervicalgia Symptoms 1.04 0.996 – 1.08 0.0763 2890 28346 exclusion phecode
763
Thoracic or lumbosacral neuritis or
Thoracic or lumbosacral neuritis or radiculitis, unspecified
 Symptoms 1.02 0.968 – 1.07 0.471 1630 22858 exclusion phecode
764 Sciatica Symptoms 1.06 1.01 – 1.12 0.0285 1501 22500 exclusion phecode
765 Cervical radiculitis Symptoms 1.06 0.981 – 1.14 0.148 764 12337 exclusion phecode
766 Neuralgia, neuritis, and radiculitis NOS Symptoms 1.05 1 – 1.09 0.031 2348 26443 exclusion phecode
767 Cervicocranial/Cervicobrachial syndrome Symptoms 0.852 0.612 – 1.19 0.341 36 805 exclusion phecode
769 Nonallopathic lesions NEC Symptoms 1.03 0.94 – 1.14 0.486 441 7477 exclusion phecode
770 Myalgia and myositis unspecified Symptoms 1.06 1.02 – 1.11 0.00568 2458 24248 exclusion phecode
771 Musculoskeletal symptoms referable to limbs Symptoms 1 0.96 – 1.05 0.911 2333 25616 exclusion phecode
771.1 Swelling of limb Symptoms 1 0.961 – 1.04 0.944 2577 25561 exclusion phecode
771.2 Cramp of limb Symptoms 0.96 0.863 – 1.07 0.451 359 7300 exclusion phecode
772 Symptoms of the muscles Symptoms 0.968 0.905 – 1.03 0.332 941 14118 exclusion phecode
772.1 Muscular wasting and disuse atrophy Symptoms 1.04 0.907 – 1.19 0.571 231 3039 exclusion phecode
772.2 Spasm of muscle Symptoms 0.986 0.924 – 1.05 0.674 975 16071 exclusion phecode
772.3 Muscle weakness Symptoms 0.991 0.937 – 1.05 0.768 1306 19361 exclusion phecode
772.4 Rhabdomyolysis Symptoms 1.36 1.06 – 1.76 0.016 64 1120 exclusion phecode
772.6 Facial weakness Symptoms 0.972 0.842 – 1.12 0.699 195 3274 exclusion phecode
780 Hypothermia/Chills Symptoms 0.904 0.777 – 1.05 0.193 176 2955 exclusion phecode
781
Symptoms involving nervous and musculoskeletal
Symptoms involving nervous and musculoskeletal systems
 Symptoms 0.983 0.923 – 1.05 0.596 1064 17724 exclusion phecode
781.1 Loss of height Symptoms 1.03 0.799 – 1.34 0.801 59 819 exclusion phecode
781.2 Abnormal posture Symptoms 0.85 0.552 – 1.31 0.461 18 388 exclusion phecode
782.3 Edema Symptoms 0.997 0.956 – 1.04 0.875 2470 25986 exclusion phecode
782.6 Pallor and flushing Symptoms 0.994 0.903 – 1.09 0.905 442 6576 exclusion phecode
783 Fever of unknown origin Symptoms 1.02 0.979 – 1.06 0.37 2817 28615 exclusion phecode
783.1 Postprocedural fever Symptoms 1.17 0.995 – 1.38 0.0575 161 2067 exclusion phecode
785 Abdominal pain Symptoms 1.01 0.987 – 1.04 0.364 8959 22676 exclusion phecode
788 Syncope and collapse Symptoms 0.961 0.915 – 1.01 0.121 1698 24695 exclusion phecode
789 Nausea and vomiting Symptoms 1.02 0.987 – 1.05 0.287 5713 25863 exclusion phecode
789.1 Persistent vomiting Symptoms 1.08 0.969 – 1.2 0.168 368 5757 exclusion phecode
790 Nonspecific findings on examination of blood Symptoms 0.94 0.882 – 1 0.0602 1012 16081 exclusion phecode
790.1 Elevated sedimentation rate Symptoms 1.15 0.921 – 1.42 0.221 84 1664 exclusion phecode
790.6 Other abnormal blood chemistry Symptoms 0.99 0.954 – 1.03 0.604 3272 27455 exclusion phecode
790.8 Elevated C-reactive protein (CRP) Symptoms 1.17 0.981 – 1.4 0.0799 130 2234 exclusion phecode
790.9 Abnormal arterial blood gases Symptoms 1.17 0.912 – 1.51 0.213 59 1098 exclusion phecode
791 Gangrene Symptoms 1.07 0.9 – 1.26 0.458 144 1992 exclusion phecode
792
Abnormal Papanicolaou smear of cervix and
Abnormal Papanicolaou smear of cervix and cervical HPV
 Genitourinary 0.962 0.913 – 1.01 0.141 1679 10901 exclusion phecode
792.1
Papanicolaou smear of cervix or vagina with
Papanicolaou smear of cervix or vagina with atypical squamous cells
 Genitourinary 0.97 0.896 – 1.05 0.459 669 7415 exclusion phecode
794
Abnormal results of other function studies
Abnormal results of other function studies (bladder, pancreas, placenta, spleen, etc)
 Symptoms 0.976 0.87 – 1.1 0.686 316 3333 exclusion phecode
795
Other and nonspecific abnormal cytological
Other and nonspecific abnormal cytological, histological and immunological findings
 Symptoms 0.938 0.886 – 0.993 0.0284 1320 14158 exclusion phecode
795.8 Abnormal tumor markers Symptoms 0.978 0.916 – 1.04 0.495 1048 9787 exclusion phecode
795.81 Elevated carcinoembryonic antigen [CEA] Symptoms 1 0.718 – 1.4 0.98 39 406 exclusion phecode
795.82 Elevated cancer antigen 125 [CA 125] Symptoms 0.805 0.672 – 0.964 0.0185 131 1325 exclusion phecode
796 Elevated prostate specific antigen [PSA] Genitourinary 0.977 0.918 – 1.04 0.466 1244 6435 exclusion phecode
797 Shock Symptoms 1.07 0.941 – 1.22 0.297 245 3909 exclusion phecode
797.1 Cardiogenic shock Symptoms 0.988 0.794 – 1.23 0.917 87 1525 exclusion phecode
798 Malaise and fatigue Symptoms 1.01 0.979 – 1.04 0.549 5028 26588 exclusion phecode
798.1 Chronic fatigue syndrome Symptoms 1.01 0.927 – 1.09 0.879 607 13266 exclusion phecode
800 Fracture of lower limb Injuries & Poisonings 0.941 0.887 – 0.997 0.0404 1245 16074 exclusion phecode
800.1 Fracture of neck of femur Injuries & Poisonings 0.942 0.83 – 1.07 0.356 261 3455 exclusion phecode
800.2 Fracture of unspecified part of femur Injuries & Poisonings 0.994 0.89 – 1.11 0.911 353 4651 exclusion phecode
800.3 Fracture of tibia and fibula Injuries & Poisonings 0.945 0.86 – 1.04 0.249 472 6377 exclusion phecode
800.4 Fracture of patella Injuries & Poisonings 0.994 0.853 – 1.16 0.941 173 2485 exclusion phecode
801 Fracture of ankle and foot Injuries & Poisonings 0.946 0.89 – 1.01 0.075 1141 15872 exclusion phecode
801.1 Fracture of foot Injuries & Poisonings 0.909 0.835 – 0.99 0.0279 582 7830 exclusion phecode
802 Fracture of pelvis Injuries & Poisonings 0.992 0.861 – 1.14 0.911 207 2647 exclusion phecode
803 Fracture of upper limb Injuries & Poisonings 0.935 0.88 – 0.993 0.0281 1192 14255 exclusion phecode
803.1 Fracture of humerus Injuries & Poisonings 0.999 0.902 – 1.11 0.978 416 5164 exclusion phecode
803.2 Fracture of radius and ulna Injuries & Poisonings 0.903 0.832 – 0.98 0.0141 642 7827 exclusion phecode
803.21 Colles' fracture Injuries & Poisonings 0.926 0.787 – 1.09 0.355 158 2016 exclusion phecode
803.3 Fracture of clavicle or scapula Injuries & Poisonings 0.855 0.759 – 0.963 0.0101 303 3612 exclusion phecode
804 Fracture of hand or wrist Injuries & Poisonings 0.963 0.9 – 1.03 0.28 925 11347 exclusion phecode
805
Fracture of vertebral column without mention of
Fracture of vertebral column without mention of spinal cord injury
 Injuries & Poisonings 0.955 0.881 – 1.03 0.254 672 9121 exclusion phecode
807 Fracture of ribs Injuries & Poisonings 0.964 0.858 – 1.08 0.533 310 4633 exclusion phecode
809 Fracture of unspecified bones Injuries & Poisonings 0.945 0.898 – 0.994 0.0285 1637 20134 exclusion phecode
816 Cerebral laceration and contusion Injuries & Poisonings 0.765 0.516 – 1.13 0.182 24 351 exclusion phecode
817 Concussion Injuries & Poisonings 1.03 0.942 – 1.14 0.482 480 7170 exclusion phecode
818 Intracranial hemorrhage (injury) Injuries & Poisonings 0.997 0.837 – 1.19 0.976 132 2042 exclusion phecode
818.1 Subdural hemorrhage (injury) Injuries & Poisonings 0.958 0.665 – 1.38 0.817 28 590 exclusion phecode
818.2 Subarachnoid hemorrhage (injury) Injuries & Poisonings 1.02 0.747 – 1.38 0.916 40 654 exclusion phecode
819
Skull and face fracture and other intercranial
Skull and face fracture and other intercranial injury
 Injuries & Poisonings 0.974 0.918 – 1.03 0.398 1170 15849 exclusion phecode
830 Dislocation Injuries & Poisonings 0.982 0.939 – 1.03 0.425 2136 24103 exclusion phecode
835 Internal derangement of knee Injuries & Poisonings 0.969 0.913 – 1.03 0.307 1206 15034 exclusion phecode
836 Traumatic arthropathy Injuries & Poisonings 0.933 0.817 – 1.07 0.31 248 3305 exclusion phecode
840 Sprains and strains Injuries & Poisonings 0.973 0.941 – 1.01 0.109 4148 27027 exclusion phecode
840.1 Muscle/tendon sprain Injuries & Poisonings 0.976 0.851 – 1.12 0.723 220 3630 exclusion phecode
840.2 Rotator cuff (capsule) sprain Injuries & Poisonings 1.1 1.02 – 1.19 0.0168 723 11014 exclusion phecode
840.3 Joint/ligament sprain Injuries & Poisonings 0.951 0.904 – 1 0.056 1703 18018 exclusion phecode
841 Sprains and strains of back and neck Injuries & Poisonings 0.903 0.834 – 0.977 0.0108 685 11120 exclusion phecode
842 Other sprains and strains Injuries & Poisonings 0.991 0.916 – 1.07 0.818 700 9971 exclusion phecode
850 Hemorrhage or hematoma complicating a procedure Injuries & Poisonings 1.02 0.963 – 1.09 0.463 1157 14151 exclusion phecode
851
Complications of transplants and reattached
Complications of transplants and reattached limbs
 Injuries & Poisonings 1.07 1.01 – 1.12 0.0156 1610 18910 exclusion phecode
853 Complication of colostomy or enterostomy Injuries & Poisonings 1.05 0.92 – 1.19 0.495 258 3193 exclusion phecode
854
Complications of cardiac/vascular device
Complications of cardiac/vascular device, implant, and graft
 Injuries & Poisonings 1.06 0.995 – 1.14 0.07 938 13437 exclusion phecode
855
Complication of nervous system device, implant
Complication of nervous system device, implant, and graft
 Injuries & Poisonings 1.12 0.944 – 1.34 0.188 138 1864 exclusion phecode
856
Vascular complications of surgery and medical
Vascular complications of surgery and medical procedures
 Injuries & Poisonings 0.99 0.837 – 1.17 0.905 155 1995 exclusion phecode
857
Mechanical complication of unspecified
Mechanical complication of unspecified genitourinary device, implant, and graft
 Injuries & Poisonings 1.12 1.04 – 1.2 0.00296 779 9148 exclusion phecode
858 Complication of internal orthopedic device Injuries & Poisonings 1.06 0.997 – 1.12 0.0646 1307 15464 exclusion phecode
859
Complication due to other implant and internal
Complication due to other implant and internal device
 Injuries & Poisonings 1.06 1 – 1.13 0.0444 1174 14664 exclusion phecode
860 Bone marrow or stem cell transplant Neoplasms 0.899 0.713 – 1.13 0.366 73 1108 exclusion phecode
870 Open wounds of head; neck; and trunk Injuries & Poisonings 1.02 0.975 – 1.06 0.408 2284 25542 exclusion phecode
870.1 Open wound or laceration of eye or eyelid Injuries & Poisonings 1.23 1.01 – 1.49 0.0399 111 1411 exclusion phecode
870.2 Open wound of ear Injuries & Poisonings 0.921 0.739 – 1.15 0.466 82 1005 exclusion phecode
870.3 Other open wound of head and face Injuries & Poisonings 0.967 0.898 – 1.04 0.379 780 9194 exclusion phecode
870.4 Open wound of nose and sinus Injuries & Poisonings 0.946 0.785 – 1.14 0.555 130 1419 exclusion phecode
870.5 Open wound of lip and mouth Injuries & Poisonings 1.07 0.912 – 1.26 0.397 165 1886 exclusion phecode
870.6 Open wound of neck Injuries & Poisonings 1.19 0.999 – 1.41 0.0518 152 1449 exclusion phecode
870.8 Open wound of genital organs Injuries & Poisonings 0.938 0.759 – 1.16 0.553 91 1040 exclusion phecode
871 Open wounds of extremities Injuries & Poisonings 1.02 0.968 – 1.07 0.517 1740 22773 exclusion phecode
871.1 Open wound of hand except finger(s) Injuries & Poisonings 0.992 0.876 – 1.12 0.904 281 3930 exclusion phecode
871.2 Open wound of finger(s) Injuries & Poisonings 0.977 0.887 – 1.08 0.634 458 6694 exclusion phecode
871.3 Open wound of foot except toe(s) alone Injuries & Poisonings 1.17 1.01 – 1.35 0.0375 193 3136 exclusion phecode
871.4 Open wound of toe(s) Injuries & Poisonings 0.82 0.669 – 1 0.0548 100 1921 exclusion phecode
872 Traumatic amputation Injuries & Poisonings 1.03 0.911 – 1.16 0.652 288 3664 exclusion phecode
874 Complication of amputation stump Injuries & Poisonings 1.28 1.01 – 1.62 0.0407 68 1119 exclusion phecode
875 Non-healing surgical wound Injuries & Poisonings 1.09 0.974 – 1.22 0.13 332 3919 exclusion phecode
876
Posttraumatic wound infection not elsewhere
Posttraumatic wound infection not elsewhere classified
 Injuries & Poisonings 1.13 1.02 – 1.26 0.0172 393 5489 exclusion phecode
907 Injuries to the nervous system Injuries & Poisonings 1.09 1 – 1.19 0.0396 590 6896 exclusion phecode
910 Superficial injury, infected Injuries & Poisonings 0.839 0.635 – 1.11 0.219 47 754 exclusion phecode
911 Blister Injuries & Poisonings 1.07 0.882 – 1.29 0.497 112 1873 exclusion phecode
912 Insect bite Injuries & Poisonings 0.932 0.808 – 1.07 0.328 202 3241 exclusion phecode
913 Toxic effect of venom Injuries & Poisonings 0.982 0.831 – 1.16 0.836 147 2198 exclusion phecode
916 Contusion Injuries & Poisonings 1.03 0.984 – 1.08 0.196 1918 26533 exclusion phecode
930 Allergic reaction to food Injuries & Poisonings 1.04 0.932 – 1.15 0.513 377 5726 exclusion phecode
931
Contact dermatitis and other eczema due to
Contact dermatitis and other eczema due to plants [except food]
 Dermatologic 0.9 0.805 – 1.01 0.0673 330 5134 exclusion phecode
938 Dermatitis due to solar radiation Dermatologic 0.914 0.878 – 0.951 1.06e-05 2824 21202 exclusion phecode
938.1 Acute dermatitis due to solar radiation Dermatologic 0.855 0.686 – 1.06 0.161 87 1613 exclusion phecode
938.2 Chronic dermatitis due to solar radiation Dermatologic 0.914 0.877 – 0.952 1.84e-05 2683 20821 exclusion phecode
939
Atopic/contact dermatitis due to other or
Atopic/contact dermatitis due to other or unspecified
 Dermatologic 0.932 0.897 – 0.967 0.000235 3163 24098 exclusion phecode
939.1 Contact and allergic dermatitis of eyelid Dermatologic 0.953 0.701 – 1.3 0.757 42 647 exclusion phecode
941 Adverse reaction to serum or vaccine Injuries & Poisonings 1.2 0.95 – 1.52 0.125 72 1344 exclusion phecode
942 Infusion and transfusion reaction Injuries & Poisonings 0.993 0.834 – 1.18 0.94 135 2007 exclusion phecode
946 Anaphylactic shock NOS Injuries & Poisonings 0.893 0.778 – 1.02 0.105 219 3618 exclusion phecode
947 Urticaria Dermatologic 0.973 0.894 – 1.06 0.523 580 8657 exclusion phecode
949 Allergies, other Injuries & Poisonings 0.977 0.943 – 1.01 0.206 3568 24060 exclusion phecode
952
Spinal cord injury without evidence of spinal
Spinal cord injury without evidence of spinal bone injury
 Injuries & Poisonings 1.05 0.928 – 1.2 0.421 271 3318 exclusion phecode
957 Injury to other and unspecified nerves Injuries & Poisonings 1.23 0.973 – 1.54 0.0844 77 958 exclusion phecode
958
Certain early complications of trauma or
Certain early complications of trauma or procedure
 Injuries & Poisonings 1.11 1.03 – 1.21 0.00831 673 8226 exclusion phecode
958.1 Postoperative shock Injuries & Poisonings 1.11 0.885 – 1.4 0.358 83 1107 exclusion phecode
958.2 Traumatic and surgical subcutaneous emphysema Injuries & Poisonings 1.09 0.829 – 1.43 0.545 59 757 exclusion phecode
960 Poisoning by antibiotics Injuries & Poisonings 0.992 0.937 – 1.05 0.784 1315 15714 exclusion phecode
960.1
Adverse effects of antibacterials (not
Adverse effects of antibacterials (not penicillins)
 Injuries & Poisonings 0.988 0.834 – 1.17 0.893 141 2389 exclusion phecode
960.2 Allergy/adverse effect of penicillin Injuries & Poisonings 1.02 0.956 – 1.1 0.49 885 11359 exclusion phecode
961 Poisoning by other anti-infectives Injuries & Poisonings 1.14 0.999 – 1.31 0.0513 224 3681 exclusion phecode
961.1 Poisoning/allergy of sulfonamides Injuries & Poisonings 1.09 0.996 – 1.19 0.062 545 7279 exclusion phecode
962 Poisoning by hormones and synthetic substitutes Injuries & Poisonings 1.04 0.93 – 1.17 0.476 314 5506 exclusion phecode
962.1
Adrenal cortical steroids causing adverse
Adrenal cortical steroids causing adverse effects in therapeutic use
 Injuries & Poisonings 0.987 0.84 – 1.16 0.876 151 2622 exclusion phecode
962.2
Insulins and antidiabetic agents causing
Insulins and antidiabetic agents causing adverse effects in therapeutic use
 Injuries & Poisonings 0.827 0.565 – 1.21 0.327 24 391 exclusion phecode
962.3
Hormones and synthetic substitutes causing
Hormones and synthetic substitutes causing adverse effects in therapeutic use
 Injuries & Poisonings 1.08 0.933 – 1.26 0.292 180 3300 exclusion phecode
963 Poisoning by primarily systemic agents Injuries & Poisonings 0.971 0.919 – 1.03 0.298 1394 17244 exclusion phecode
963.1
Antineoplastic and immunosuppressive drugs
Antineoplastic and immunosuppressive drugs causing adverse effects
 Injuries & Poisonings 0.973 0.92 – 1.03 0.332 1371 16900 exclusion phecode
964
Poisoning by agents primarily affecting blood
Poisoning by agents primarily affecting blood constituents
 Injuries & Poisonings 0.991 0.879 – 1.12 0.881 284 5055 exclusion phecode
964.1 Anticoagulants causing adverse effects Injuries & Poisonings 1.01 0.889 – 1.14 0.929 266 4829 exclusion phecode
965
Poisoning by analgesics, antipyretics, and
Poisoning by analgesics, antipyretics, and antirheumatics
 Injuries & Poisonings 1.04 0.94 – 1.15 0.454 419 6170 exclusion phecode
965.1
Opiates and related narcotics causing adverse
Opiates and related narcotics causing adverse effects in therapeutic use
 Injuries & Poisonings 1.08 1 – 1.17 0.0427 691 10261 exclusion phecode
965.3
Salicylates causing adverse effects in
Salicylates causing adverse effects in therapeutic use
 Injuries & Poisonings 0.974 0.779 – 1.22 0.818 82 810 exclusion phecode
966
Poisoning by anticonvulsants and
Poisoning by anticonvulsants and anti-Parkinsonism drugs
 Injuries & Poisonings 1.16 0.857 – 1.57 0.333 37 711 exclusion phecode
967
Adverse effects of sedatives or other central
Adverse effects of sedatives or other central nervous system depressants and anesthetics
 Injuries & Poisonings 1.03 0.951 – 1.12 0.432 600 8877 exclusion phecode
969 Poisoning by psychotropic agents Injuries & Poisonings 1.27 1.02 – 1.57 0.033 82 2043 exclusion phecode
971
Poisoning by drugs primarily affecting the
Poisoning by drugs primarily affecting the autonomic nervous system
 Injuries & Poisonings 0.946 0.661 – 1.35 0.761 29 436 exclusion phecode
972
Poisoning by agents primarily affecting the
Poisoning by agents primarily affecting the cardiovascular system
 Injuries & Poisonings 0.931 0.767 – 1.13 0.467 109 1941 exclusion phecode
972.1
Cardiac rhythm regulators causing adverse
Cardiac rhythm regulators causing adverse effects in therapeutic use
 Injuries & Poisonings 0.658 0.46 – 0.941 0.0217 34 539 exclusion phecode
972.6 Antihypertensive agents causing adverse effects Injuries & Poisonings 1.07 0.794 – 1.45 0.647 42 669 exclusion phecode
974
Poisoning by water, mineral, and uric acid
Poisoning by water, mineral, and uric acid metabolism drugs
 Injuries & Poisonings 0.885 0.616 – 1.27 0.509 26 776 exclusion phecode
975
Poisoning by agents primarily acting on the
Poisoning by agents primarily acting on the smooth and skeletal muscles and respiratory system
 Injuries & Poisonings 1.17 0.789 – 1.74 0.432 25 568 exclusion phecode
976
Poisoning by agents primarily affecting skin &
Poisoning by agents primarily affecting skin & mucous membrane, ophthalmological, otorhinolaryngological, & dental drugs
 Injuries & Poisonings 1.07 0.771 – 1.48 0.687 34 485 exclusion phecode
977 Personal history of allergy to medicinal agents Injuries & Poisonings 1.06 0.981 – 1.14 0.144 784 11726 exclusion phecode
979 Adverse drug events and drug allergies Injuries & Poisonings 0.994 0.943 – 1.05 0.818 1543 21978 exclusion phecode
980
Encounter for long-term (current) use of
Encounter for long-term (current) use of antibiotics
 Infectious Diseases 0.953 0.883 – 1.03 0.209 737 9087 exclusion phecode
985 Toxic effect of other metals Injuries & Poisonings 0.94 0.612 – 1.44 0.775 19 337 exclusion phecode
989
Toxic effect of other substances, chiefly
Toxic effect of other substances, chiefly nonmedicinal as to source
 Injuries & Poisonings 1.1 0.831 – 1.46 0.508 48 784 exclusion phecode
990 Effects radiation NOS Injuries & Poisonings 0.992 0.951 – 1.03 0.705 2502 20747 exclusion phecode
994 Sepsis and SIRS Injuries & Poisonings 1.08 1.01 – 1.16 0.0174 974 14356 exclusion phecode
994.1 Systemic inflammatory response syndrome (SIRS) Injuries & Poisonings 0.912 0.76 – 1.09 0.323 122 1942 exclusion phecode
994.2 Sepsis Injuries & Poisonings 1.11 1.04 – 1.18 0.00309 925 13676 exclusion phecode
994.21 Septic shock Injuries & Poisonings 1.14 1 – 1.29 0.0503 256 4055 exclusion phecode
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