Departments of Anesthesiology and Biostatistics | University of Michigan

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Scores Direct LDL cholesterol (IRNT) Michigan Genomics Initiative Freeze 3 (MGI) PheWAS analysis

Direct LDL cholesterol (IRNT) — Michigan Genomics Initiative Freeze 3 (MGI) PRS PheWAS

PRS model
PRS ID exprsweb-ldl-30780-irnt-lassosum-mgi-freeze3-20211120Legacy LASSOSUMlassosumUK Biobank GWAS

Evaluation cohort: Michigan Genomics Initiative Freeze 3 (MGI).

This page pairs the PheWAS plot with the full sortable table for the all-subject and exclusion scans.

Read the all-subject and exclusion scans separately. The combined view is only a browsing aid, and the selected-phecode panel below is only meaningful when the same phecode exists in both scans.

ExPRS exclusion definition

Exclusion cohort: normal-range subset (0.01-100).

For this ExPRS, the exclusion sensitivity scan keeps only the study's normal-range subset for Direct LDL cholesterol (IRNT) (0.01-100) before rerunning the PheWAS. This is an exposure-based sensitivity analysis rather than a diagnosis-based exclusion.

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Signal overview

The plot gives a quick view of the currently visible associations. Click a point to pin its details, inspect that phecode across scans when both rows exist, or open the matching phecode detail page.

131 rows visible 16 categories
Phecode Description Category OR 95% CI P value Cases Controls Analysis Link
008 Intestinal infection Infectious Diseases 0.979 0.943 – 1.02 0.275 3004 29292 all phecode
008.5 Bacterial enteritis Infectious Diseases 0.976 0.922 – 1.03 0.413 1322 13162 all phecode
008.52 Intestinal infection due to C. difficile Infectious Diseases 0.994 0.932 – 1.06 0.861 1046 10455 all phecode
008.6 Viral Enteritis Infectious Diseases 1 0.931 – 1.08 0.923 770 7676 all phecode
010 Tuberculosis Infectious Diseases 0.966 0.847 – 1.1 0.611 244 2425 all phecode
031 Diseases due to other mycobacteria Infectious Diseases 0.853 0.681 – 1.07 0.164 86 855 all phecode
038 Septicemia Infectious Diseases 1 0.963 – 1.04 0.895 2582 24779 all phecode
038.1 Gram negative septicemia Infectious Diseases 0.968 0.888 – 1.06 0.462 568 5629 all phecode
038.2 Gram positive septicemia Infectious Diseases 0.991 0.867 – 1.13 0.893 235 2350 all phecode
038.3 Bacteremia Infectious Diseases 1 0.945 – 1.06 0.93 1210 12079 all phecode
041 Bacterial infection NOS Infectious Diseases 1.01 0.979 – 1.04 0.648 5750 38799 all phecode
041.1 Staphylococcus infections Infectious Diseases 0.989 0.94 – 1.04 0.655 1707 16977 all phecode
041.11 Methicillin sensitive Staphylococcus aureus Infectious Diseases 0.965 0.902 – 1.03 0.312 920 9192 all phecode
041.12 Methicillin resistant Staphylococcus aureus Infectious Diseases 1.01 0.936 – 1.09 0.826 783 7812 all phecode
041.2 Streptococcus infection Infectious Diseases 0.964 0.916 – 1.01 0.16 1632 16287 all phecode
041.21 Rheumatic fever / chorea Infectious Diseases 1.01 0.886 – 1.15 0.91 257 2554 all phecode
041.4 E. coli Infectious Diseases 1.02 0.959 – 1.08 0.539 1175 11680 all phecode
041.8 H. pylori Infectious Diseases 1.02 0.892 – 1.16 0.816 257 2521 all phecode
041.9 Infection with drug-resistant microorganisms Infectious Diseases 1.02 0.915 – 1.13 0.747 387 3864 all phecode
053 Herpes zoster Infectious Diseases 1 0.953 – 1.06 0.875 1560 15184 all phecode
053.1 Herpes zoster with nervous system complications Infectious Diseases 0.906 0.788 – 1.04 0.164 220 2169 all phecode
054 Herpes simplex Infectious Diseases 1 0.953 – 1.06 0.891 1593 15600 all phecode
070 Viral hepatitis Infectious Diseases 0.987 0.919 – 1.06 0.726 829 8280 all phecode
070.1 Viral hepatitis A Infectious Diseases 0.925 0.736 – 1.16 0.506 87 860 all phecode
070.2 Viral hepatitis B Infectious Diseases 0.976 0.847 – 1.12 0.736 215 2138 all phecode
070.3 Viral hepatitis C Infectious Diseases 0.969 0.886 – 1.06 0.495 528 5280 all phecode
070.4 Chronic hepatitis Infectious Diseases 0.931 0.804 – 1.08 0.338 197 1964 all phecode
070.9 Hepatitis NOS Infectious Diseases 0.976 0.918 – 1.04 0.439 1145 11381 all phecode
071 Human immunodeficiency virus [HIV] disease Infectious Diseases 1.1 0.924 – 1.3 0.294 145 1450 all phecode
071.1 HIV infection, symptomatic Infectious Diseases 1.17 0.963 – 1.42 0.115 117 1163 all phecode
078 Viral warts & HPV Infectious Diseases 0.998 0.963 – 1.03 0.911 3434 29624 all phecode
079 Viral infection Infectious Diseases 1.02 0.995 – 1.05 0.116 6664 35342 all phecode
079.1 Varicella infection Infectious Diseases 1.02 0.987 – 1.06 0.238 3793 31251 all phecode
079.2 Infectious mononucleosis Infectious Diseases 1.04 0.92 – 1.18 0.525 283 2723 all phecode
079.9 Viremia, NOS Infectious Diseases 1.02 0.947 – 1.09 0.647 838 8253 all phecode
080 Postoperative infection Infectious Diseases 0.988 0.949 – 1.03 0.568 2619 26065 all phecode
081
Infection/inflammation of internal prosthetic
Infection/inflammation of internal prosthetic device; implant; and graft
 Infectious Diseases 0.955 0.906 – 1.01 0.0815 1589 15884 all phecode
090
Sexually transmitted infections (not HIV or
Sexually transmitted infections (not HIV or hepatitis)
 Infectious Diseases 1.05 0.982 – 1.12 0.153 965 9630 all phecode
110 Dermatophytosis / Dermatomycosis Infectious Diseases 0.992 0.957 – 1.03 0.643 3544 30054 all phecode
110.1 Dermatophytosis Infectious Diseases 0.995 0.958 – 1.03 0.777 3241 27244 all phecode
110.11 Dermatophytosis of nail Infectious Diseases 1.01 0.96 – 1.05 0.791 2044 16765 all phecode
110.12 Althete's foot Infectious Diseases 1.01 0.941 – 1.08 0.801 899 8043 all phecode
110.13 Dermatophytosis of the body Infectious Diseases 1.02 0.946 – 1.1 0.626 790 7827 all phecode
110.2 Dermatomycoses Infectious Diseases 0.959 0.865 – 1.06 0.418 398 3971 all phecode
112 Candidiasis Infectious Diseases 0.994 0.96 – 1.03 0.724 3685 30495 all phecode
112.3 Candidiasis of skin and nails Infectious Diseases 0.982 0.907 – 1.06 0.643 682 6732 all phecode
117 Mycoses Infectious Diseases 1.01 0.931 – 1.1 0.768 608 6069 all phecode
117.1 Histoplasmosis Infectious Diseases 1.04 0.829 – 1.31 0.729 81 801 all phecode
117.4 Aspergillosis Infectious Diseases 1.1 0.921 – 1.31 0.292 140 1387 all phecode
130 Spirochetal infection Infectious Diseases 0.944 0.805 – 1.11 0.482 168 1677 all phecode
130.1 Lyme disease Infectious Diseases 1.01 0.831 – 1.22 0.948 116 1160 all phecode
131 Protozoan infection Infectious Diseases 0.948 0.728 – 1.23 0.693 61 610 all phecode
132 Infestation (lice, mites) Infectious Diseases 0.896 0.773 – 1.04 0.146 195 1948 all phecode
134 Helminthiases Infectious Diseases 0.906 0.728 – 1.13 0.377 83 812 all phecode
134.1 Intestinal helminthiases Infectious Diseases 0.94 0.716 – 1.23 0.654 53 513 all phecode
136 Other infectious and parasitic diseases Infectious Diseases 0.993 0.958 – 1.03 0.708 3279 32486 all phecode
145 Cancer of mouth Neoplasms 0.972 0.922 – 1.03 0.3 1481 14725 all phecode
145.1 Cancer of lip Neoplasms 0.92 0.732 – 1.16 0.472 76 750 all phecode
145.2 Cancer of tongue Neoplasms 0.942 0.87 – 1.02 0.15 645 6430 all phecode
145.3 Cancer of major salivary glands Neoplasms 1.02 0.918 – 1.14 0.667 361 3597 all phecode
145.4 Cancer of the gums Neoplasms 0.888 0.759 – 1.04 0.142 166 1632 all phecode
145.5 Cancer of the mouth floor Neoplasms 0.9 0.783 – 1.03 0.14 206 2048 all phecode
149 Cancer of larynx, pharynx, nasal cavities Neoplasms 0.961 0.908 – 1.02 0.173 1290 12873 all phecode
149.1 Cancer of oropharynx Neoplasms 1.05 0.938 – 1.17 0.415 350 3499 all phecode
149.2 Cancer of nasopharynx Neoplasms 0.893 0.728 – 1.1 0.282 100 1000 all phecode
149.3 Cancer of hypopharynx Neoplasms 1.12 0.896 – 1.4 0.318 82 819 all phecode
149.4 Cancer of larynx Neoplasms 0.96 0.865 – 1.07 0.442 386 3857 all phecode
149.5
Hx of malignant neoplasm of oral cavity and
Hx of malignant neoplasm of oral cavity and pharynx
 Neoplasms 0.916 0.839 – 0.999 0.0487 552 5505 all phecode
149.9 Cancer of of nasal cavities Neoplasms 0.967 0.847 – 1.1 0.625 240 2398 all phecode
150 Cancer of esophagus Neoplasms 0.992 0.899 – 1.1 0.875 433 4315 all phecode
151 Cancer of stomach Neoplasms 0.991 0.904 – 1.09 0.854 498 4962 all phecode
153 Colorectal cancer Neoplasms 1.06 0.999 – 1.11 0.0543 1458 14383 all phecode
153.2 Colon cancer Neoplasms 1.07 1.01 – 1.14 0.0281 1160 11472 all phecode
153.3
Malignant neoplasm of rectum, rectosigmoid
Malignant neoplasm of rectum, rectosigmoid junction, and anus
 Neoplasms 1.04 0.964 – 1.12 0.334 815 8093 all phecode
155 Cancer of liver and intrahepatic bile duct Neoplasms 1.02 0.931 – 1.12 0.655 511 5097 all phecode
155.1 Malignant neoplasm of liver, primary Neoplasms 1.01 0.901 – 1.13 0.871 344 3433 all phecode
157 Pancreatic cancer Neoplasms 0.972 0.887 – 1.07 0.547 503 5005 all phecode
158
Neoplasm of unspecified nature of digestive
Neoplasm of unspecified nature of digestive system
 Neoplasms 0.955 0.907 – 1.01 0.0783 1623 15759 all phecode
159
Malignant neoplasm of other and ill-defined
Malignant neoplasm of other and ill-defined sites within the digestive organs and peritoneum
 Neoplasms 1.03 0.977 – 1.08 0.306 1818 17869 all phecode
159.2
Malignant neoplasm of small intestine
Malignant neoplasm of small intestine, including duodenum
 Neoplasms 1.24 1.08 – 1.42 0.00225 221 2206 all phecode
159.3
Malignant neoplasm of gallbladder and
Malignant neoplasm of gallbladder and extrahepatic bile ducts
 Neoplasms 0.912 0.773 – 1.08 0.274 158 1578 all phecode
159.4
Malignant neoplasm of retroperitoneum and
Malignant neoplasm of retroperitoneum and peritoneum
 Neoplasms 1.04 0.92 – 1.17 0.548 293 2920 all phecode
164 Cancer of intrathoracic organs Neoplasms 1.03 0.869 – 1.23 0.71 133 1324 all phecode
165 Cancer within the respiratory system Neoplasms 0.99 0.935 – 1.05 0.716 1336 13340 all phecode
165.1 Cancer of bronchus; lung Neoplasms 0.982 0.922 – 1.05 0.576 1057 10552 all phecode
170 Cancer of bone and connective tissue Neoplasms 0.996 0.949 – 1.05 0.874 1792 17850 all phecode
170.1 Bone cancer Neoplasms 0.927 0.861 – 0.998 0.0443 773 7690 all phecode
170.2 Cancer of connective tissue Neoplasms 1.01 0.955 – 1.07 0.675 1266 12632 all phecode
172 Skin cancer Neoplasms 0.984 0.96 – 1.01 0.194 8608 33186 all phecode
172.1 Melanomas of skin, dx or hx Neoplasms 0.986 0.957 – 1.02 0.369 5330 30106 all phecode
172.11 Melanomas of skin Neoplasms 0.977 0.941 – 1.01 0.233 3100 25064 all phecode
172.2 Other non-epithelial cancer of skin Neoplasms 0.98 0.954 – 1.01 0.144 7095 30462 all phecode
172.21 Basal cell carcinoma Neoplasms 1.01 0.977 – 1.05 0.49 3690 23868 all phecode
172.22 Squamous cell carcinoma Neoplasms 0.998 0.956 – 1.04 0.945 2414 17683 all phecode
172.3 Carcinoma in situ of skin Neoplasms 1.04 0.99 – 1.1 0.112 1482 12326 all phecode
173 Neoplasm of uncertain behavior of skin Neoplasms 1.01 0.96 – 1.05 0.813 1997 18755 all phecode
174 Breast cancer Neoplasms 1.01 0.976 – 1.06 0.46 3186 15514 all phecode
174.1 Breast cancer [female] Neoplasms 1.02 0.982 – 1.06 0.285 3036 14701 all phecode
174.11 Malignant neoplasm of female breast Neoplasms 1.03 0.987 – 1.07 0.19 2991 14639 all phecode
174.3 Neoplasm of uncertain behavior of breast Neoplasms 1.14 0.999 – 1.31 0.0517 233 2307 all phecode
175 Acquired absence of breast Neoplasms 1.05 0.976 – 1.12 0.2 919 8920 all phecode
180 Cervical cancer and dysplasia Neoplasms 0.994 0.94 – 1.05 0.823 1431 12185 all phecode
180.1 Cervical cancer Neoplasms 0.97 0.885 – 1.06 0.524 500 4982 all phecode
180.3
Cervical intraepithelial neoplasia [CIN]
Cervical intraepithelial neoplasia [CIN] [Cervical dysplasia]
 Neoplasms 0.988 0.927 – 1.05 0.725 1048 9323 all phecode
182 Malignant neoplasm of uterus Neoplasms 0.945 0.877 – 1.02 0.144 765 7613 all phecode
184 Cancer of other female genital organs Neoplasms 0.97 0.913 – 1.03 0.315 1191 11592 all phecode
184.1
Malignant neoplasm of ovary and other uterine
Malignant neoplasm of ovary and other uterine adnexa
 Neoplasms 0.967 0.887 – 1.05 0.45 573 5719 all phecode
184.11 Malignant neoplasm of ovary Neoplasms 0.998 0.902 – 1.1 0.964 432 4309 all phecode
184.2
Cancer of other female genital organs
Cancer of other female genital organs (excluding uterus and ovary)
 Neoplasms 0.921 0.847 – 1 0.056 608 6057 all phecode
185 Cancer of prostate Neoplasms 1.01 0.97 – 1.06 0.581 2901 10342 all phecode
187 Cancer of other male genital organs Neoplasms 0.99 0.886 – 1.11 0.863 339 3384 all phecode
187.1
Malignant neoplasm of unspecified male genital
Malignant neoplasm of unspecified male genital organ
 Neoplasms 1.09 0.897 – 1.32 0.386 115 1141 all phecode
187.2 Malignant neoplasm of testis Neoplasms 0.92 0.789 – 1.07 0.285 183 1830 all phecode
187.8
Neoplasm of uncertain behavior of male genital
Neoplasm of uncertain behavior of male genital organs
 Neoplasms 0.956 0.73 – 1.25 0.745 57 562 all phecode
189
Cancer of urinary organs (incl. kidney and
Cancer of urinary organs (incl. kidney and bladder)
 Neoplasms 0.996 0.958 – 1.04 0.849 2923 23541 all phecode
189.1 Cancer of kidney and renal pelvis Neoplasms 1.01 0.957 – 1.07 0.702 1450 14437 all phecode
189.11 Malignant neoplasm of kidney, except pelvis Neoplasms 1.02 0.963 – 1.08 0.49 1267 12655 all phecode
189.12 Malignant neoplasm of renal pelvis Neoplasms 0.986 0.862 – 1.13 0.835 237 2347 all phecode
189.2 Cancer of bladder Neoplasms 0.993 0.945 – 1.04 0.768 1783 15224 all phecode
189.21 Malignant neoplasm of bladder Neoplasms 0.98 0.932 – 1.03 0.449 1657 14178 all phecode
189.4 Malignant neoplasm of other urinary organs Neoplasms 1.01 0.933 – 1.09 0.809 678 6586 all phecode
190 Cancer of eye Neoplasms 1 0.835 – 1.2 0.991 138 1374 all phecode
191
Manlignant and unknown neoplasms of brain and
Manlignant and unknown neoplasms of brain and nervous system
 Neoplasms 0.979 0.919 – 1.04 0.512 1078 10771 all phecode
191.1 Cancer of brain and nervous system Neoplasms 0.981 0.908 – 1.06 0.632 706 7052 all phecode
191.11 Cancer of brain Neoplasms 1 0.923 – 1.09 0.934 600 5996 all phecode
193 Thyroid cancer Neoplasms 0.971 0.908 – 1.04 0.395 945 9393 all phecode
194 Cancer of other endocrine glands Neoplasms 0.965 0.886 – 1.05 0.416 579 5759 all phecode
195 Cancer, suspected or other Neoplasms 1.01 0.985 – 1.03 0.615 16962 26401 all phecode
195.1 Malignant neoplasm, other Neoplasms 1.01 0.986 – 1.03 0.525 16670 26384 all phecode
195.3 Malignant neoplasm of head, face, and neck Neoplasms 0.992 0.932 – 1.06 0.791 1103 9766 all phecode
196 Radiotherapy Neoplasms 1.01 0.971 – 1.06 0.527 2427 17006 all phecode
197 Chemotherapy Neoplasms 1.03 0.995 – 1.06 0.1 4952 23797 all phecode
198 Secondary malignant neoplasm Neoplasms 1.01 0.985 – 1.05 0.345 5801 23481 all phecode
198.1 Secondary malignancy of lymph nodes Neoplasms 1 0.968 – 1.04 0.865 3677 21489 all phecode
198.2 Secondary malignancy of respiratory organs Neoplasms 0.979 0.918 – 1.04 0.507 1072 10334 all phecode
198.3
Secondary malignant neoplasm of digestive
Secondary malignant neoplasm of digestive systems
 Neoplasms 1 0.935 – 1.08 0.905 866 8538 all phecode
198.4 Secondary malignant neoplasm of liver Neoplasms 1.07 0.99 – 1.15 0.09 767 7558 all phecode
198.5 Secondary malignancy of brain/spine Neoplasms 0.971 0.895 – 1.05 0.483 640 6338 all phecode
198.6 Secondary malignancy of bone Neoplasms 1.05 0.981 – 1.13 0.153 866 8307 all phecode
198.7 Secondary malignant neoplasm of skin Neoplasms 1 0.897 – 1.12 0.957 336 3253 all phecode
199 Neoplasm of uncertain behavior Neoplasms 0.998 0.969 – 1.03 0.883 5693 25767 all phecode
199.4 Neurofibromatosis Neoplasms 1.06 0.851 – 1.32 0.609 88 880 all phecode
200 Myeloproliferative disease Neoplasms 1.01 0.949 – 1.07 0.752 1113 11098 all phecode
200.1 Polycythemia vera Neoplasms 1.02 0.892 – 1.16 0.805 231 2310 all phecode
201 Hodgkin's disease Neoplasms 0.91 0.779 – 1.06 0.235 172 1705 all phecode
202 Cancer of other lymphoid, histiocytic tissue Neoplasms 0.99 0.939 – 1.04 0.696 1559 15571 all phecode
202.2 Non-Hodgkins lymphoma Neoplasms 0.975 0.921 – 1.03 0.386 1329 13268 all phecode
202.21 Nodular lymphoma Neoplasms 0.931 0.861 – 1.01 0.075 693 6923 all phecode
202.22 Reticulosarcoma Neoplasms 1 0.858 – 1.17 0.981 170 1693 all phecode
202.24 Large cell lymphoma Neoplasms 1.02 0.867 – 1.2 0.821 160 1586 all phecode
204 Leukemia Neoplasms 1 0.926 – 1.08 0.96 689 6876 all phecode
204.1 Lymphoid leukemia Neoplasms 0.937 0.819 – 1.07 0.338 236 2354 all phecode
204.11 Lymphoid leukemia, acute Neoplasms 0.992 0.779 – 1.26 0.949 74 734 all phecode
204.12 Lymphoid leukemia, chronic Neoplasms 0.917 0.786 – 1.07 0.272 173 1724 all phecode
204.2 Myeloid leukemia Neoplasms 1.02 0.897 – 1.15 0.783 265 2633 all phecode
204.21 Myeloid leukemia, acute Neoplasms 0.953 0.804 – 1.13 0.575 153 1516 all phecode
204.22 Myeloid leukemia, chronic Neoplasms 1.07 0.829 – 1.38 0.61 61 610 all phecode
204.4 Multiple myeloma Neoplasms 1.02 0.887 – 1.17 0.777 217 2162 all phecode
208 Benign neoplasm of colon Neoplasms 1.02 0.996 – 1.04 0.1 10303 34953 all phecode
209 Neuroendocrine tumors Neoplasms 1 0.882 – 1.14 0.957 258 2580 all phecode
210 Benign neoplasm of lip, oral cavity, and pharynx Neoplasms 0.989 0.943 – 1.04 0.648 1891 18839 all phecode
211
Benign neoplasm of other parts of digestive
Benign neoplasm of other parts of digestive system
 Neoplasms 0.985 0.961 – 1.01 0.252 7329 36606 all phecode
212
Benign neoplasm of respiratory and
Benign neoplasm of respiratory and intrathoracic organs
 Neoplasms 1.01 0.96 – 1.06 0.757 1843 18412 all phecode
213 Benign neoplasm of bone and articular cartilage Neoplasms 0.938 0.892 – 0.987 0.0145 1677 15527 all phecode
214 Lipoma Neoplasms 1.04 0.98 – 1.09 0.209 1437 14132 all phecode
214.1 Lipoma of skin and subcutaneous tissue Neoplasms 1.06 0.987 – 1.14 0.108 883 8710 all phecode
215
Other benign neoplasm of connective and other
Other benign neoplasm of connective and other soft tissue
 Neoplasms 0.972 0.942 – 1 0.0707 4528 39509 all phecode
216 Benign neoplasm of skin Neoplasms 0.997 0.976 – 1.02 0.775 11528 34919 all phecode
216.1 Screening for malignant neoplasms of the skin Neoplasms 1.02 0.87 – 1.2 0.795 174 1701 all phecode
217 Vascular hamartomas and non-neoplastic nevi Neoplasms 1.03 0.976 – 1.08 0.316 1786 17184 all phecode
217.1 Nevus, non-neoplastic Neoplasms 1.04 0.988 – 1.09 0.14 1679 16116 all phecode
218 Benign neoplasm of uterus Neoplasms 0.965 0.933 – 0.999 0.0414 4301 16661 all phecode
218.1 Uterine leiomyoma Neoplasms 0.948 0.903 – 0.996 0.0333 1835 15733 all phecode
218.2 Other benign neoplasm of uterus Neoplasms 0.962 0.927 – 0.999 0.0437 3403 16447 all phecode
220 Benign neoplasm of ovary Neoplasms 0.977 0.912 – 1.05 0.521 893 8783 all phecode
221 Benign neoplasm of other female genital organs Neoplasms 0.982 0.937 – 1.03 0.443 2042 14248 all phecode
222 Benign neoplasm of male genital organs Neoplasms 0.966 0.908 – 1.03 0.266 1133 10663 all phecode
223
Benign neoplasm of kidney and other urinary
Benign neoplasm of kidney and other urinary organs
 Neoplasms 1.02 0.972 – 1.08 0.397 1801 12657 all phecode
224 Benign neoplasm of eye Neoplasms 0.949 0.876 – 1.03 0.194 691 6752 all phecode
224.1 Benign neoplasm of eye, uveal Neoplasms 0.977 0.896 – 1.07 0.603 595 5773 all phecode
225
Benign neoplasm of brain and other parts of
Benign neoplasm of brain and other parts of nervous system
 Neoplasms 0.972 0.916 – 1.03 0.343 1209 12074 all phecode
225.1
Benign neoplasm of brain, cranial nerves
Benign neoplasm of brain, cranial nerves, meninges
 Neoplasms 0.967 0.904 – 1.03 0.32 947 9454 all phecode
225.2 Benign neoplasm of spinal cord, meninges Neoplasms 1.04 0.917 – 1.17 0.577 289 2890 all phecode
226 Benign neoplasm of thyroid glands Neoplasms 0.992 0.937 – 1.05 0.774 1329 13264 all phecode
227
Benign neoplasm of other endocrine glands and
Benign neoplasm of other endocrine glands and related structures
 Neoplasms 0.972 0.925 – 1.02 0.276 1690 16896 all phecode
227.1 Benign neoplasm of adrenal gland Neoplasms 1.1 0.999 – 1.21 0.0516 467 4644 all phecode
227.2 Benign neoplasm of parathyroid gland Neoplasms 0.951 0.884 – 1.02 0.185 795 7941 all phecode
227.3
Benign neoplasm of pituitary gland and
Benign neoplasm of pituitary gland and craniopharyngeal duct (pouch)
 Neoplasms 0.943 0.854 – 1.04 0.243 435 4350 all phecode
228 Hemangioma and lymphangioma, any site Neoplasms 1.05 1.01 – 1.1 0.0219 2149 20946 all phecode
228.1 Hemangioma of skin and subcutaneous tissue Neoplasms 1.05 0.992 – 1.11 0.0943 1356 13336 all phecode
229 Benign neoplasm of unspecified sites Neoplasms 0.989 0.965 – 1.01 0.403 7767 36615 all phecode
229.1 Benign neoplasm of lymph nodes Neoplasms 0.996 0.968 – 1.02 0.765 5743 34218 all phecode
240 Simple and unspecified goiter Endocrine/metabolic 1 0.939 – 1.07 0.956 1031 9761 all phecode
241 Nontoxic nodular goiter Endocrine/metabolic 0.981 0.943 – 1.02 0.325 2910 22227 all phecode
241.1 Nontoxic uninodular goiter Endocrine/metabolic 0.99 0.947 – 1.03 0.655 2265 19902 all phecode
241.2 Nontoxic multinodular goiter Endocrine/metabolic 0.987 0.932 – 1.05 0.663 1304 12479 all phecode
242 Thyrotoxicosis with or without goiter Endocrine/metabolic 0.964 0.912 – 1.02 0.199 1400 13425 all phecode
242.1 Graves' disease Endocrine/metabolic 0.95 0.868 – 1.04 0.276 515 5068 all phecode
242.2 Toxic multinodular goiter Endocrine/metabolic 1.04 0.854 – 1.26 0.724 124 1224 all phecode
242.3 Exophthalmos Endocrine/metabolic 1.06 0.941 – 1.2 0.334 292 2898 all phecode
242.31 Thyrotoxic exophthalmos Endocrine/metabolic 0.898 0.754 – 1.07 0.225 144 1432 all phecode
244 Hypothyroidism Endocrine/metabolic 0.981 0.956 – 1.01 0.136 8099 32717 all phecode
244.1 Secondary hypothyroidism Endocrine/metabolic 0.963 0.917 – 1.01 0.141 1762 17230 all phecode
244.2 Acquired hypothyroidism Endocrine/metabolic 1.04 0.977 – 1.1 0.23 1261 11982 all phecode
244.4 Hypothyroidism NOS Endocrine/metabolic 0.984 0.958 – 1.01 0.215 7542 32208 all phecode
245 Thyroiditis Endocrine/metabolic 0.987 0.918 – 1.06 0.72 832 7882 all phecode
245.2 Chronic thyroiditis Endocrine/metabolic 0.975 0.9 – 1.06 0.538 686 6517 all phecode
245.21 Chronic lymphocytic thyroiditis Endocrine/metabolic 0.972 0.897 – 1.05 0.489 679 6449 all phecode
246 Other disorders of thyroid Endocrine/metabolic 0.952 0.926 – 0.98 0.000723 6129 30240 all phecode
246.2 Thyroid cyst Endocrine/metabolic 0.91 0.743 – 1.11 0.36 101 960 all phecode
246.7 Abnormal results of function study of thyroid Endocrine/metabolic 0.985 0.919 – 1.06 0.666 886 8696 all phecode
249 Secondary diabetes mellitus Endocrine/metabolic 0.953 0.89 – 1.02 0.177 1150 8340 all phecode
250 Diabetes mellitus Endocrine/metabolic 0.989 0.968 – 1.01 0.311 13947 31815 all phecode
250.1 Type 1 diabetes Endocrine/metabolic 0.947 0.893 – 1 0.0694 2364 11758 all phecode
250.11 Type 1 diabetes with ketoacidosis Endocrine/metabolic 0.909 0.766 – 1.08 0.276 262 960 all phecode
250.12 Type 1 diabetes with renal manifestations Endocrine/metabolic 0.929 0.826 – 1.05 0.22 551 2686 all phecode
250.13 Type 1 diabetes with ophthalmic manifestations Endocrine/metabolic 0.965 0.866 – 1.08 0.525 784 3018 all phecode
250.14 Type 1 diabetes with neurological manifestations Endocrine/metabolic 1.01 0.897 – 1.13 0.924 638 2675 all phecode
250.15
Diabetes type 1 with peripheral circulatory
Diabetes type 1 with peripheral circulatory disorders
 Endocrine/metabolic 0.899 0.737 – 1.1 0.291 155 850 all phecode
250.2 Type 2 diabetes Endocrine/metabolic 0.974 0.949 – 0.998 0.0366 9843 29688 all phecode
250.21 Type 2 diabetes with ketoacidosis Endocrine/metabolic 0.895 0.767 – 1.05 0.161 282 1327 all phecode
250.22 Type 2 diabetes with renal manifestations Endocrine/metabolic 0.969 0.918 – 1.02 0.25 1941 13510 all phecode
250.23 Type 2 diabetes with ophthalmic manifestations Endocrine/metabolic 0.977 0.916 – 1.04 0.487 1643 9668 all phecode
250.24 Type 2 diabetes with neurological manifestations Endocrine/metabolic 0.979 0.933 – 1.03 0.4 2557 16502 all phecode
250.25
Diabetes type 2 with peripheral circulatory
Diabetes type 2 with peripheral circulatory disorders
 Endocrine/metabolic 1.03 0.954 – 1.12 0.419 860 6143 all phecode
250.3 Insulin pump user Endocrine/metabolic 0.969 0.928 – 1.01 0.15 3496 20809 all phecode
250.4 Abnormal glucose Endocrine/metabolic 1.02 0.992 – 1.05 0.177 8385 30645 all phecode
250.41 Impaired fasting glucose Endocrine/metabolic 1.02 0.972 – 1.08 0.388 1870 15861 all phecode
250.42 Other abnormal glucose Endocrine/metabolic 1.02 0.994 – 1.05 0.125 7553 30071 all phecode
250.5 Glycosuria or Acetonuria Endocrine/metabolic 0.897 0.742 – 1.08 0.264 136 1067 all phecode
250.6 Polyneuropathy in diabetes Endocrine/metabolic 0.962 0.91 – 1.02 0.163 2132 13390 all phecode
250.7 Diabetic retinopathy Endocrine/metabolic 0.976 0.923 – 1.03 0.383 1691 10517 all phecode
251 Other disorders of pancreatic internal secretion Endocrine/metabolic 1.01 0.948 – 1.08 0.688 991 8469 all phecode
251.1 Hypoglycemia Endocrine/metabolic 1.03 0.964 – 1.11 0.368 1207 8570 all phecode
252 Disorders of parathyroid gland Endocrine/metabolic 1.01 0.963 – 1.05 0.786 2282 22119 all phecode
252.1 Hyperparathyroidism Endocrine/metabolic 1 0.958 – 1.05 0.897 2088 20335 all phecode
252.2 Hypoparathyroidism Endocrine/metabolic 1.03 0.937 – 1.13 0.575 508 5073 all phecode
253
Disorders of the pituitary gland and its
Disorders of the pituitary gland and its hypothalamic control
 Endocrine/metabolic 1.01 0.941 – 1.08 0.799 859 8544 all phecode
253.1 Pituitary hyperfunction Endocrine/metabolic 0.936 0.824 – 1.06 0.315 263 2621 all phecode
253.11 Acromegaly and gigantism Endocrine/metabolic 0.996 0.797 – 1.25 0.973 83 826 all phecode
253.2 Pituitary hypofunction Endocrine/metabolic 0.987 0.861 – 1.13 0.851 226 2250 all phecode
253.3 Diabetes insipidus Endocrine/metabolic 0.869 0.693 – 1.09 0.225 86 860 all phecode
253.4 Anterior pituitary disorders Endocrine/metabolic 0.949 0.786 – 1.15 0.584 121 1209 all phecode
253.7 Other disorders of neurohypophysis Endocrine/metabolic 1.24 1.03 – 1.49 0.0265 108 1080 all phecode
255 Disorders of adrenal glands Endocrine/metabolic 0.959 0.909 – 1.01 0.129 1506 14869 all phecode
255.1 Adrenal hyperfunction Endocrine/metabolic 0.967 0.868 – 1.08 0.55 373 3730 all phecode
255.11 Cushing's syndrome Endocrine/metabolic 0.986 0.846 – 1.15 0.859 183 1830 all phecode
255.12 Hyperaldosteronism Endocrine/metabolic 1.1 0.924 – 1.32 0.278 135 1350 all phecode
255.2 Adrenal hypofunction Endocrine/metabolic 0.954 0.878 – 1.04 0.257 626 6239 all phecode
255.21 Glucocorticoid deficiency Endocrine/metabolic 0.945 0.868 – 1.03 0.191 596 5941 all phecode
256 Ovarian dysfunction Endocrine/metabolic 0.974 0.915 – 1.04 0.392 1146 10513 all phecode
256.4 Polycystic ovaries Endocrine/metabolic 0.985 0.912 – 1.06 0.696 742 7128 all phecode
257 Testicular dysfunction Endocrine/metabolic 1.01 0.946 – 1.08 0.75 1015 9238 all phecode
257.1 Testicular hypofunction Endocrine/metabolic 1.02 0.955 – 1.09 0.548 983 8933 all phecode
258 Iatrogenic endocrine disorders Endocrine/metabolic 0.974 0.781 – 1.21 0.816 91 910 all phecode
258.1 Postablative ovarian failure Endocrine/metabolic 0.894 0.736 – 1.09 0.262 109 1090 all phecode
259 Other endocrine disorders Endocrine/metabolic 0.988 0.926 – 1.05 0.722 1038 10259 all phecode
260 Protein-calorie malnutrition Endocrine/metabolic 1.02 0.983 – 1.06 0.283 2880 26812 all phecode
260.1 Cachexia Endocrine/metabolic 1.08 0.957 – 1.21 0.216 292 2911 all phecode
260.2 severe protein-calorie malnutrition Endocrine/metabolic 1.03 0.979 – 1.08 0.259 1691 16847 all phecode
260.22 Nutritional marasmus Endocrine/metabolic 1.03 0.951 – 1.12 0.432 614 6140 all phecode
260.3 Adult failure to thrive Endocrine/metabolic 1.04 0.96 – 1.13 0.324 629 6236 all phecode
260.6 Anorexia Endocrine/metabolic 1.07 0.994 – 1.14 0.0746 868 8591 all phecode
260.7 Polyphagia Endocrine/metabolic 1.13 0.867 – 1.47 0.37 65 643 all phecode
261 Vitamin deficiency Endocrine/metabolic 1.01 0.985 – 1.04 0.403 7718 35203 all phecode
261.1 Vitamin A deficiency Endocrine/metabolic 1 0.782 – 1.28 0.994 69 690 all phecode
261.2 Vitamin B-complex deficiencies Endocrine/metabolic 1 0.935 – 1.08 0.932 857 8405 all phecode
261.4 Vitamin D deficiency Endocrine/metabolic 1.01 0.988 – 1.04 0.304 7255 35225 all phecode
261.41 Rickets or osteomalacia Endocrine/metabolic 1.04 0.781 – 1.38 0.8 52 511 all phecode
262 Mineral deficiency NEC Endocrine/metabolic 1.01 0.954 – 1.08 0.673 1182 11676 all phecode
263 Other nutritional deficiency Endocrine/metabolic 1 0.951 – 1.05 0.974 1651 15788 all phecode
264 Lack of normal physiological development Endocrine/metabolic 1.03 0.896 – 1.18 0.709 239 2301 all phecode
264.2 Failure to thrive (childhood) Endocrine/metabolic 1.05 0.866 – 1.26 0.641 122 1220 all phecode
264.9
Lack of normal physiological development
Lack of normal physiological development, unspecified
 Endocrine/metabolic 1.01 0.8 – 1.27 0.96 81 772 all phecode
269 Proteinuria Endocrine/metabolic 1.04 0.986 – 1.09 0.152 1694 13981 all phecode
270
Disorders of protein plasma/amino-acid
Disorders of protein plasma/amino-acid transport and metabolism
 Endocrine/metabolic 1 0.94 – 1.07 0.897 967 9575 all phecode
270.1 Disturbances of amino-acid transport Endocrine/metabolic 0.896 0.764 – 1.05 0.174 170 1697 all phecode
270.11
Disturbances of sulphur-bearing amino-acid
Disturbances of sulphur-bearing amino-acid metabolism
 Endocrine/metabolic 0.845 0.704 – 1.01 0.0698 134 1334 all phecode
270.2 Disorders of amino-acid metabolism Endocrine/metabolic 0.817 0.662 – 1.01 0.0602 96 954 all phecode
270.3 Disorders of plasma protein metabolism Endocrine/metabolic 1.06 0.979 – 1.14 0.159 737 7303 all phecode
270.32 Paraproteinemia Endocrine/metabolic 1.03 0.925 – 1.14 0.608 384 3781 all phecode
270.33 Amyloidosis Endocrine/metabolic 1.09 0.861 – 1.37 0.483 71 695 all phecode
270.34 Alpha-1-antitrypsin deficiency Endocrine/metabolic 1.06 0.838 – 1.34 0.623 69 690 all phecode
270.38
Other specified disorders of plasma protein
Other specified disorders of plasma protein metabolism
 Endocrine/metabolic 1.07 0.951 – 1.21 0.251 299 2984 all phecode
271
Disorders of carbohydrate transport and
Disorders of carbohydrate transport and metabolism
 Endocrine/metabolic 1.02 0.985 – 1.06 0.232 2907 28132 all phecode
271.3
Intestinal disaccharidase deficiencies and
Intestinal disaccharidase deficiencies and disaccharide malabsorption
 Endocrine/metabolic 1.03 0.988 – 1.07 0.182 2827 27425 all phecode
271.9
Other disorders of carbohydrate transport and
Other disorders of carbohydrate transport and metabolism
 Endocrine/metabolic 0.901 0.743 – 1.09 0.293 102 1007 all phecode
272 Disorders of lipoid metabolism Endocrine/metabolic 1.34 1.31 – 1.37 2.78e-158 18881 26670 all phecode
272.1 Hyperlipidemia Endocrine/metabolic 1.34 1.31 – 1.37 2.48e-159 18843 26654 all phecode
272.11 Hypercholesterolemia Endocrine/metabolic 1.46 1.42 – 1.51 3.3e-120 5928 21600 all phecode
272.12 Hyperglyceridemia Endocrine/metabolic 1.19 1.13 – 1.26 2.29e-09 1360 11837 all phecode
272.13 Mixed hyperlipidemia Endocrine/metabolic 1.38 1.33 – 1.44 3.6e-58 3538 18449 all phecode
272.9 Unspecified disorder of lipoid metabolism Endocrine/metabolic 1.19 1.06 – 1.34 0.00416 313 3011 all phecode
274 Gout and other crystal arthropathies Endocrine/metabolic 1 0.961 – 1.04 0.929 2524 22729 all phecode
274.1 Gout Endocrine/metabolic 1.01 0.967 – 1.05 0.684 2409 21991 all phecode
274.11 Gouty arthropathy Endocrine/metabolic 1.01 0.951 – 1.08 0.698 1082 10576 all phecode
274.2 Crystal arthropathies Endocrine/metabolic 1.02 0.875 – 1.18 0.817 195 1890 all phecode
274.21 Chondrocalcinosis Endocrine/metabolic 1.01 0.868 – 1.18 0.868 183 1772 all phecode
275 Disorders of mineral metabolism Endocrine/metabolic 0.985 0.955 – 1.02 0.36 4357 37091 all phecode
275.1 Disorders of iron metabolism Hematopoietic 0.833 0.725 – 0.957 0.0101 218 2180 all phecode
275.11 Hereditary hemochromatosis Hematopoietic 0.764 0.628 – 0.931 0.00757 99 990 all phecode
275.2 Disorders of copper metabolism Endocrine/metabolic 0.986 0.761 – 1.28 0.912 62 614 all phecode
275.3 Disorders of magnesium metabolism Endocrine/metabolic 1.01 0.952 – 1.08 0.71 1154 11504 all phecode
275.5 Disorders of calcium/phosphorus metabolism Endocrine/metabolic 0.977 0.943 – 1.01 0.203 3369 31544 all phecode
275.51 Hypocalcemia Endocrine/metabolic 0.951 0.888 – 1.02 0.152 898 8969 all phecode
275.53 Disorders of phosphorus metabolism Endocrine/metabolic 0.963 0.911 – 1.02 0.183 1366 13634 all phecode
275.6 Hypercalcemia Endocrine/metabolic 1.01 0.957 – 1.07 0.709 1468 14183 all phecode
276
Disorders of fluid, electrolyte, and acid-base
Disorders of fluid, electrolyte, and acid-base balance
 Endocrine/metabolic 1.01 0.991 – 1.04 0.222 9238 37046 all phecode
276.1 Electrolyte imbalance Endocrine/metabolic 1.01 0.984 – 1.04 0.426 6352 34366 all phecode
276.11 Hyperosmolality and/or hypernatremia Endocrine/metabolic 0.979 0.898 – 1.07 0.641 550 5434 all phecode
276.12 Hyposmolality and/or hyponatremia Endocrine/metabolic 1.01 0.969 – 1.05 0.651 2514 23219 all phecode
276.13 Hyperpotassemia Endocrine/metabolic 0.996 0.959 – 1.04 0.844 2992 25216 all phecode
276.14 Hypopotassemia Endocrine/metabolic 1.02 0.972 – 1.06 0.465 2148 20909 all phecode
276.4 Acid-base balance disorder Endocrine/metabolic 1.01 0.963 – 1.05 0.745 2086 20332 all phecode
276.41 Acidosis Endocrine/metabolic 1 0.952 – 1.05 0.987 1788 17572 all phecode
276.42 Alkalosis Endocrine/metabolic 1.08 0.986 – 1.19 0.0958 476 4741 all phecode
276.5 Hypovolemia Endocrine/metabolic 1.02 0.99 – 1.05 0.18 4574 34527 all phecode
276.6 Fluid overload Endocrine/metabolic 0.969 0.916 – 1.02 0.263 1384 13211 all phecode
276.8 Polydipsia Endocrine/metabolic 1.2 0.993 – 1.45 0.0593 124 1240 all phecode
277 Other disorders of metabolism Endocrine/metabolic 0.999 0.967 – 1.03 0.973 4112 35070 all phecode
277.2
Other disorders of purine and pyrimidine
Other disorders of purine and pyrimidine metabolism
 Endocrine/metabolic 1.03 0.927 – 1.15 0.566 403 3991 all phecode
277.4 Disorders of bilirubin excretion Endocrine/metabolic 0.996 0.923 – 1.08 0.928 720 7161 all phecode
277.5 Other disorders of lipoid metabolism Endocrine/metabolic 0.937 0.876 – 1 0.0617 936 9270 all phecode
277.51 Lipoprotein disorders Endocrine/metabolic 0.931 0.864 – 1 0.0634 773 7668 all phecode
277.7 Dysmetabolic syndrome X Endocrine/metabolic 1.03 0.959 – 1.1 0.452 916 8359 all phecode
278 Overweight, obesity and other hyperalimentation Endocrine/metabolic 0.98 0.962 – 0.998 0.033 19419 27331 all phecode
278.1 Obesity Endocrine/metabolic 0.974 0.955 – 0.993 0.00773 17129 27321 all phecode
278.11 Morbid obesity Endocrine/metabolic 0.965 0.941 – 0.989 0.00497 8280 27172 all phecode
278.3 Localized adiposity Endocrine/metabolic 0.874 0.78 – 0.98 0.0208 324 3228 all phecode
278.4 Abnormal weight gain Endocrine/metabolic 0.975 0.931 – 1.02 0.292 2104 17411 all phecode
279 Disorders involving the immune mechanism Endocrine/metabolic 0.959 0.923 – 0.997 0.0341 2934 28612 all phecode
279.1 Immunity deficiency Endocrine/metabolic 0.957 0.9 – 1.02 0.159 1161 11571 all phecode
279.11 Deficiency of humoral immunity Endocrine/metabolic 0.996 0.889 – 1.12 0.948 330 3278 all phecode
279.2 Autoimmune disease NEC Endocrine/metabolic 0.927 0.861 – 1 0.049 754 7516 all phecode
279.7 Other immunological findings Endocrine/metabolic 1.01 0.976 – 1.04 0.704 4885 36552 all phecode
279.8
Other specified disorders involving the immune
Other specified disorders involving the immune mechanism
 Endocrine/metabolic 0.93 0.856 – 1.01 0.0859 601 5988 all phecode
280 Iron deficiency anemias Hematopoietic 1.03 0.998 – 1.06 0.0626 4626 30873 all phecode
280.1
Iron deficiency anemias, unspecified or not due
Iron deficiency anemias, unspecified or not due to blood loss
 Hematopoietic 1.02 0.993 – 1.06 0.129 4484 30649 all phecode
280.2
Iron deficiency anemia secondary to blood loss
Iron deficiency anemia secondary to blood loss (chronic)
 Hematopoietic 1.01 0.961 – 1.06 0.688 1771 17196 all phecode
281 Other deficiency anemia Hematopoietic 0.999 0.912 – 1.09 0.98 519 5120 all phecode
281.1 Megaloblastic anemia Hematopoietic 0.96 0.844 – 1.09 0.529 253 2497 all phecode
281.11 Pernicious anemia Hematopoietic 0.912 0.751 – 1.11 0.349 114 1108 all phecode
281.12 Other vitamin B12 deficiency anemia Hematopoietic 0.959 0.826 – 1.11 0.581 187 1817 all phecode
281.9 Deficiency anemias Hematopoietic 1.06 0.931 – 1.2 0.396 285 2830 all phecode
282 Hereditary hemolytic anemias Hematopoietic 0.969 0.863 – 1.09 0.59 323 3188 all phecode
282.8 Other hemoglobinopathies Hematopoietic 0.887 0.769 – 1.02 0.0993 216 2113 all phecode
282.9 Other hereditary hemolytic anemias Hematopoietic 1.04 0.899 – 1.21 0.583 192 1920 all phecode
283 Acquired hemolytic anemias Hematopoietic 1.05 0.888 – 1.25 0.544 155 1550 all phecode
283.1 Autoimmune hemolytic anemias Hematopoietic 1.22 0.936 – 1.59 0.143 64 633 all phecode
284 Aplastic anemia Hematopoietic 1.05 0.966 – 1.13 0.273 697 6943 all phecode
284.1 Pancytopenia Hematopoietic 1.05 0.964 – 1.14 0.27 612 6100 all phecode
285 Other anemias Hematopoietic 1.01 0.992 – 1.04 0.232 11794 33591 all phecode
285.1 Acute posthemorrhagic anemia Hematopoietic 1.03 0.991 – 1.07 0.145 3325 27709 all phecode
285.2 Anemia of chronic disease Hematopoietic 1.01 0.969 – 1.06 0.532 2055 19939 all phecode
285.21 Anemia in chronic kidney disease Hematopoietic 0.974 0.91 – 1.04 0.454 932 9106 all phecode
285.22 Anemia in neoplastic disease Hematopoietic 1.03 0.948 – 1.11 0.523 690 6892 all phecode
286 Coagulation defects Hematopoietic 1.01 0.973 – 1.04 0.732 3844 33384 all phecode
286.1 Congenital coagulation defects Hematopoietic 0.921 0.808 – 1.05 0.22 250 2466 all phecode
286.11 Von willebrand's disease Hematopoietic 1.02 0.814 – 1.29 0.845 83 822 all phecode
286.12
Congenital deficiency of other clotting factors
Congenital deficiency of other clotting factors (including factor VII)
 Hematopoietic 0.884 0.737 – 1.06 0.185 126 1260 all phecode
286.2
Encounter for long-term (current) use of
Encounter for long-term (current) use of anticoagulants
 Hematopoietic 1.02 0.984 – 1.06 0.27 3354 25918 all phecode
286.3
Coagulation defects complicating pregnancy or
Coagulation defects complicating pregnancy or postpartum
 Hematopoietic 0.741 0.603 – 0.909 0.00407 97 962 all phecode
286.4 Acquired coagulation factor deficiency Hematopoietic 1.01 0.884 – 1.15 0.92 254 2529 all phecode
286.5
Hemorrhagic disorder due to intrinsic
Hemorrhagic disorder due to intrinsic circulating anticoagulants
 Hematopoietic 1.06 0.89 – 1.27 0.503 132 1294 all phecode
286.6 Defibrination syndrome Hematopoietic 1.02 0.98 – 1.06 0.315 2579 25377 all phecode
286.7 Other and unspecified coagulation defects Hematopoietic 1.01 0.969 – 1.05 0.741 3014 29294 all phecode
286.8 Hypercoagulable state Hematopoietic 1.01 0.938 – 1.08 0.864 846 8437 all phecode
286.81 Primary hypercoagulable state Hematopoietic 1 0.931 – 1.07 0.993 813 8111 all phecode
286.9 Abnormal coagulation profile Hematopoietic 1.02 0.956 – 1.08 0.613 1182 11487 all phecode
287 Purpura and other hemorrhagic conditions Hematopoietic 1.04 1 – 1.08 0.033 3288 28474 all phecode
287.1 Spontaneous ecchymoses Hematopoietic 0.964 0.837 – 1.11 0.607 211 2094 all phecode
287.3 Thrombocytopenia Hematopoietic 1.04 1 – 1.08 0.034 2938 26323 all phecode
287.31 Primary thrombocytopenia Hematopoietic 1.01 0.933 – 1.1 0.731 601 5994 all phecode
287.32 Secondary thrombocytopenia Hematopoietic 1.04 0.956 – 1.14 0.347 569 5686 all phecode
287.4 Qualitative platelet defects Hematopoietic 1.13 0.941 – 1.37 0.188 112 1120 all phecode
288 Diseases of white blood cells Hematopoietic 0.988 0.959 – 1.02 0.431 4886 36527 all phecode
288.1 Decreased white blood cell count Hematopoietic 1.01 0.957 – 1.06 0.756 1599 15951 all phecode
288.11 Neutropenia Hematopoietic 0.987 0.927 – 1.05 0.682 1106 11041 all phecode
288.2 Elevated white blood cell count Hematopoietic 0.978 0.946 – 1.01 0.177 4082 35079 all phecode
288.3 Eosinophilia Hematopoietic 0.906 0.783 – 1.05 0.184 187 1866 all phecode
289 Other diseases of blood and blood-forming organs Hematopoietic 0.967 0.921 – 1.02 0.186 1757 17434 all phecode
289.3
Personal history of diseases of blood and
Personal history of diseases of blood and blood-forming organs
 Hematopoietic 1.01 0.947 – 1.09 0.698 918 9087 all phecode
289.4 Lymphadenitis Hematopoietic 0.983 0.951 – 1.02 0.325 3888 34715 all phecode
289.5 Diseases of spleen Hematopoietic 1.02 0.913 – 1.13 0.78 393 3913 all phecode
289.8 Polycythemia, secondary Hematopoietic 0.906 0.798 – 1.03 0.125 255 2550 all phecode
289.9 Abnormality of red blood cells Hematopoietic 0.952 0.859 – 1.06 0.352 385 3813 all phecode
290
Delirium dementia and amnestic and other
Delirium dementia and amnestic and other cognitive disorders
 Mental Disorders 1.04 0.984 – 1.1 0.158 1318 11547 all phecode
290.1 Dementias Mental Disorders 1.09 1 – 1.19 0.0492 541 4910 all phecode
290.11 Alzheimer's disease Mental Disorders 1.04 0.882 – 1.24 0.615 151 1389 all phecode
290.12 Dementia with cerebral degenerations Mental Disorders 0.887 0.714 – 1.1 0.277 88 846 all phecode
290.13 Senile dementia Mental Disorders 1.08 0.964 – 1.2 0.188 340 3078 all phecode
290.16 Vascular dementia Mental Disorders 1.05 0.83 – 1.32 0.7 81 777 all phecode
290.2 Delirium due to conditions classified elsewhere Mental Disorders 1 0.932 – 1.08 0.899 750 7358 all phecode
290.3
Other persistent mental disorders due to
Other persistent mental disorders due to conditions classified elsewhere
 Mental Disorders 1.06 0.99 – 1.14 0.0918 886 8618 all phecode
291
Other specified nonpsychotic and/or transient
Other specified nonpsychotic and/or transient mental disorders
 Mental Disorders 0.997 0.957 – 1.04 0.904 2550 24810 all phecode
291.1
Transient mental disorders due to conditions
Transient mental disorders due to conditions classified elsewhere
 Mental Disorders 0.995 0.858 – 1.15 0.948 175 1750 all phecode
291.4
Specific nonpsychotic mental disorders due to
Specific nonpsychotic mental disorders due to brain damage
 Mental Disorders 1.02 0.925 – 1.11 0.744 484 4807 all phecode
291.8 Alteration of consciousness Mental Disorders 1 0.956 – 1.05 0.96 2036 19974 all phecode
292 Neurological disorders Mental Disorders 0.991 0.963 – 1.02 0.527 5733 38553 all phecode
292.1 Aphasia/speech disturbance Mental Disorders 0.974 0.93 – 1.02 0.261 2013 19867 all phecode
292.11 Aphasia Mental Disorders 0.982 0.906 – 1.07 0.666 664 6581 all phecode
292.12 Symbolic dysfunction Mental Disorders 0.92 0.795 – 1.07 0.268 200 1988 all phecode
292.2 Mild cognitive impairment Mental Disorders 1.07 0.962 – 1.19 0.213 389 3731 all phecode
292.3 Memory loss Mental Disorders 1.05 1 – 1.1 0.0519 1922 18158 all phecode
292.4 Altered mental status Mental Disorders 0.985 0.945 – 1.03 0.489 2454 22725 all phecode
292.5 Transient alteration of awareness Mental Disorders 0.968 0.876 – 1.07 0.525 430 4285 all phecode
292.6 Hallucinations Mental Disorders 0.868 0.758 – 0.994 0.0401 217 2147 all phecode
293 Symptoms involving head and neck Mental Disorders 0.991 0.895 – 1.1 0.865 414 4127 all phecode
293.1
Swelling, mass, or lump in head and neck
Swelling, mass, or lump in head and neck [Space-occupying lesion, intracranial NOS]
 Mental Disorders 1.01 0.974 – 1.04 0.75 4417 38609 all phecode
295 Schizophrenia and other psychotic disorders Mental Disorders 0.963 0.897 – 1.03 0.293 885 8229 all phecode
295.1 Schizophrenia Mental Disorders 0.937 0.781 – 1.12 0.483 138 1339 all phecode
295.2 Paranoid disorders Mental Disorders 0.795 0.655 – 0.965 0.0203 118 1079 all phecode
295.3 Psychosis Mental Disorders 0.979 0.905 – 1.06 0.604 716 6694 all phecode
296 Mood disorders Mental Disorders 1.01 0.988 – 1.03 0.405 15356 20858 all phecode
296.1 Bipolar Mental Disorders 0.996 0.939 – 1.06 0.9 1301 11264 all phecode
296.2 Depression Mental Disorders 1.01 0.988 – 1.03 0.371 14833 20856 all phecode
296.22 Major depressive disorder Mental Disorders 1.01 0.987 – 1.03 0.43 13850 20853 all phecode
297 Suicidal ideation or attempt Mental Disorders 0.984 0.919 – 1.05 0.646 985 9050 all phecode
297.1 Suicidal ideation Mental Disorders 0.99 0.918 – 1.07 0.803 788 7310 all phecode
297.2 Suicide or self-inflicted injury Mental Disorders 1.04 0.916 – 1.18 0.562 285 2654 all phecode
300 Anxiety disorders Mental Disorders 1.01 0.992 – 1.04 0.229 15419 20850 all phecode
300.1 Anxiety disorder Mental Disorders 1.01 0.99 – 1.03 0.288 14517 20855 all phecode
300.11 Generalized anxiety disorder Mental Disorders 0.996 0.965 – 1.03 0.787 5546 20512 all phecode
300.12 Agorophobia, social phobia, and panic disorder Mental Disorders 0.995 0.938 – 1.06 0.88 1360 11377 all phecode
300.13 Phobia Mental Disorders 0.99 0.926 – 1.06 0.764 1051 9542 all phecode
300.3 Obsessive-compulsive disorders Mental Disorders 0.944 0.838 – 1.06 0.335 328 3018 all phecode
300.4 Dysthymic disorder Mental Disorders 1.01 0.967 – 1.06 0.628 2420 16552 all phecode
300.8 Acute reaction to stress Mental Disorders 0.972 0.885 – 1.07 0.556 504 4825 all phecode
300.9 Posttraumatic stress disorder Mental Disorders 0.999 0.928 – 1.07 0.976 843 7909 all phecode
301 Personality disorders Mental Disorders 1.01 0.919 – 1.12 0.792 477 4539 all phecode
301.2 Antisocial/borderline personality disorder Mental Disorders 1.07 0.936 – 1.23 0.319 254 2393 all phecode
302 Sexual and gender identity disorders Mental Disorders 0.987 0.95 – 1.02 0.484 3700 13808 all phecode
302.1 Decreased libido Mental Disorders 0.933 0.844 – 1.03 0.176 447 4331 all phecode
303 Psychogenic and somatoform disorders Mental Disorders 1.02 0.995 – 1.05 0.113 6808 20043 all phecode
303.1 Dissociative disorder Mental Disorders 0.912 0.775 – 1.07 0.269 161 1573 all phecode
303.3 Psychogenic disorder Mental Disorders 1.02 0.991 – 1.05 0.188 6487 19888 all phecode
303.31
Gastrointestinal malfunction arising from
Gastrointestinal malfunction arising from mental factors
 Mental Disorders 0.94 0.853 – 1.04 0.212 471 4623 all phecode
303.4 Somatoform disorder Mental Disorders 1.02 0.964 – 1.09 0.435 1177 11180 all phecode
304 Adjustment reaction Mental Disorders 1 0.97 – 1.04 0.789 3888 20475 all phecode
305.2 Eating disorder Mental Disorders 0.934 0.87 – 1 0.0563 901 8329 all phecode
306 Other mental disorder Mental Disorders 0.977 0.929 – 1.03 0.36 1815 14133 all phecode
306.1 Mental disorders durring/after pregnancy Mental Disorders 1.06 0.972 – 1.17 0.175 587 3527 all phecode
306.9 Tension headache Mental Disorders 0.953 0.883 – 1.03 0.214 753 7277 all phecode
312 Conduct disorders Mental Disorders 0.972 0.856 – 1.1 0.658 254 2501 all phecode
312.3 Impulse control disorder Mental Disorders 0.879 0.695 – 1.11 0.278 74 736 all phecode
313 Pervasive developmental disorders Mental Disorders 1.01 0.955 – 1.06 0.799 1571 14633 all phecode
313.1 Attention deficit hyperactivity disorder Mental Disorders 0.993 0.939 – 1.05 0.81 1392 13190 all phecode
313.2 Tics and stuttering Mental Disorders 1.17 0.929 – 1.48 0.181 77 770 all phecode
313.3 Autism Mental Disorders 1.09 0.843 – 1.42 0.502 64 621 all phecode
315 Develomental delays and disorders Mental Disorders 1.03 0.956 – 1.12 0.395 684 6788 all phecode
315.1 Learning disorder Mental Disorders 1.05 0.839 – 1.3 0.691 87 860 all phecode
315.2 Speech and language disorder Mental Disorders 1.1 0.963 – 1.25 0.16 254 2539 all phecode
316 Substance addiction and disorders Mental Disorders 1 0.967 – 1.04 0.95 3682 32680 all phecode
316.1 Polyneuropathy due to drugs Mental Disorders 1.01 0.927 – 1.09 0.875 634 6331 all phecode
317 Alcohol-related disorders Mental Disorders 1.02 0.983 – 1.07 0.252 2525 22920 all phecode
317.1 Alcoholism Mental Disorders 1.02 0.97 – 1.06 0.496 1986 19339 all phecode
317.11 Alcoholic liver damage Mental Disorders 0.989 0.893 – 1.1 0.836 408 4080 all phecode
318 Tobacco use disorder Mental Disorders 1.02 0.995 – 1.04 0.129 8622 34842 all phecode
320 Meningitis Neurological 1.04 0.934 – 1.15 0.5 382 3820 all phecode
323 Encephalitis Neurological 1.01 0.874 – 1.18 0.852 181 1809 all phecode
323.8 Encephalitis, non-infectious Neurological 0.988 0.842 – 1.16 0.883 153 1527 all phecode
324 Other CNS infection and poliomyelitis Neurological 0.993 0.88 – 1.12 0.915 288 2880 all phecode
325
Phlebitis and thrombophlebitis of intracranial
Phlebitis and thrombophlebitis of intracranial venous sinuses
 Neurological 0.878 0.661 – 1.17 0.367 53 530 all phecode
327 Sleep disorders Neurological 0.997 0.978 – 1.02 0.797 14941 31602 all phecode
327.1 Hypersomnia Neurological 1.01 0.963 – 1.06 0.743 2061 19110 all phecode
327.3 Sleep apnea Neurological 1 0.98 – 1.03 0.834 10909 31304 all phecode
327.31 Central/nonobstroctive sleep apnea Neurological 0.975 0.889 – 1.07 0.593 492 4784 all phecode
327.32 Obstructive sleep apnea Neurological 1 0.976 – 1.03 0.967 8744 30530 all phecode
327.4 Insomnia Neurological 0.99 0.962 – 1.02 0.505 5524 30960 all phecode
327.41 Organic or persistent insomnia Neurological 0.986 0.93 – 1.05 0.63 1265 12120 all phecode
327.5 Parasomnia Neurological 0.942 0.865 – 1.03 0.166 604 5913 all phecode
327.6 Circadian rhythm sleep disorder Neurological 0.842 0.74 – 0.957 0.00873 274 2666 all phecode
327.7 Sleep related movement disorders Neurological 0.944 0.899 – 0.992 0.0216 1786 17323 all phecode
327.71 Restless legs syndrome Neurological 0.928 0.881 – 0.978 0.00489 1570 15360 all phecode
327.72 Sleep related leg cramps Neurological 0.989 0.795 – 1.23 0.919 83 822 all phecode
331 Other cerebral degenerations Neurological 1.02 0.946 – 1.1 0.597 717 7024 all phecode
331.1 Hydrocephalus Neurological 0.987 0.874 – 1.12 0.834 284 2836 all phecode
331.9 Cerebral degeneration, unspecified Neurological 1.01 0.91 – 1.11 0.918 419 4026 all phecode
332 Parkinson's disease Neurological 0.908 0.82 – 1.01 0.0626 415 4128 all phecode
333
Extrapyramidal disease and abnormal movement
Extrapyramidal disease and abnormal movement disorders
 Neurological 0.966 0.929 – 1 0.0823 2868 26583 all phecode
333.1 Essential tremor Neurological 0.984 0.912 – 1.06 0.673 725 7163 all phecode
333.2 Myoclonus Neurological 1.16 0.983 – 1.37 0.0788 159 1590 all phecode
333.4 Torsion dystonia Neurological 1.03 0.922 – 1.15 0.602 352 3504 all phecode
333.8 Other degenerative diseases of the basal ganglia Neurological 0.993 0.794 – 1.24 0.954 89 890 all phecode
334 Degenerative disease of the spinal cord Neurological 0.958 0.899 – 1.02 0.185 1058 10562 all phecode
334.1 Spinocerebellar disease Neurological 0.707 0.552 – 0.905 0.006 79 790 all phecode
334.2 Anterior horn cell disease Neurological 0.802 0.659 – 0.976 0.0276 110 1080 all phecode
334.21 Amyotrophic Lateral Sclerosis Neurological 0.701 0.552 – 0.891 0.00368 71 693 all phecode
335 Multiple sclerosis Neurological 1.01 0.911 – 1.12 0.846 396 3951 all phecode
337 Disorders of the autonomic nervous system Neurological 0.957 0.889 – 1.03 0.239 808 7413 all phecode
337.1 Peripheral autonomic neuropathy Neurological 0.964 0.863 – 1.08 0.516 370 3164 all phecode
338 Pain Neurological 1.01 0.995 – 1.03 0.156 20346 26417 all phecode
338.1 Acute pain Neurological 1.01 0.991 – 1.03 0.303 15582 26313 all phecode
338.2 Chronic pain Neurological 1.02 0.993 – 1.04 0.186 10994 26368 all phecode
339 Other headache syndromes Neurological 1 0.977 – 1.02 0.987 9242 34658 all phecode
340 Migraine Neurological 0.991 0.964 – 1.02 0.502 6708 30587 all phecode
340.1 Migrain with aura Neurological 1.01 0.978 – 1.05 0.466 3624 23684 all phecode
341
Other demyelinating diseases of central nervous
Other demyelinating diseases of central nervous system
 Neurological 0.946 0.79 – 1.13 0.547 133 1330 all phecode
342 Hemiplegia Neurological 0.967 0.88 – 1.06 0.49 464 4607 all phecode
343 Infantile cerebral palsy Neurological 1.11 0.888 – 1.38 0.365 85 847 all phecode
344 Other paralytic syndromes Neurological 1.02 0.944 – 1.11 0.591 682 6808 all phecode
345 Epilepsy, recurrent seizures, convulsions Neurological 0.952 0.914 – 0.992 0.0194 2553 25307 all phecode
345.1 Epilepsy Neurological 0.897 0.832 – 0.967 0.00475 747 7465 all phecode
345.11 Generalized convulsive epilepsy Neurological 0.916 0.801 – 1.05 0.199 233 2330 all phecode
345.12 Partial epilepsy Neurological 0.91 0.833 – 0.995 0.0384 534 5335 all phecode
345.3 Convulsions Neurological 0.948 0.908 – 0.989 0.0136 2396 23796 all phecode
346
Abnormal findings on study of brain and/or
Abnormal findings on study of brain and/or nervous system
 Neurological 0.936 0.804 – 1.09 0.396 183 1824 all phecode
346.1
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of skull and head
 Neurological 0.965 0.914 – 1.02 0.194 1472 14587 all phecode
346.2
Nonspecific abnormal results of function study
Nonspecific abnormal results of function study of brain and central nervous system
 Neurological 0.902 0.744 – 1.09 0.297 120 1181 all phecode
346.3
Nonspecific abnormal findings in cerebrospinal
Nonspecific abnormal findings in cerebrospinal fluid
 Neurological 0.8 0.66 – 0.97 0.0232 110 1100 all phecode
347 Cataplexy and narcolepsy Neurological 0.896 0.732 – 1.1 0.287 101 1010 all phecode
348 Other conditions of brain Neurological 0.999 0.951 – 1.05 0.952 1793 17894 all phecode
348.2 Cerebral edema and compression of brain Neurological 0.977 0.912 – 1.05 0.504 905 9034 all phecode
348.4 Cerebral cysts Neurological 1.02 0.888 – 1.17 0.794 229 2290 all phecode
348.7 Coma Neurological 1.09 0.948 – 1.25 0.233 229 2275 all phecode
348.8 Encephalopathy, not elsewhere classified Neurological 1.03 0.964 – 1.11 0.355 853 8479 all phecode
348.9 Other conditions of brain, NOS Neurological 0.996 0.954 – 1.04 0.86 2341 23287 all phecode
349
Other and unspecified disorders of the nervous
Other and unspecified disorders of the nervous system
 Neurological 0.993 0.928 – 1.06 0.848 941 9385 all phecode
350 Abnormal movement Neurological 0.99 0.965 – 1.02 0.478 6706 38762 all phecode
350.1 Abnormal involuntary movements Neurological 0.995 0.96 – 1.03 0.805 3273 30524 all phecode
350.2 Abnormality of gait Neurological 0.967 0.935 – 1 0.0519 3920 30520 all phecode
350.3 Lack of coordination Neurological 0.992 0.931 – 1.06 0.816 1062 10554 all phecode
350.5 Abnormal reflex Neurological 0.941 0.815 – 1.09 0.413 200 1988 all phecode
350.6 Disturbances of sensation of smell and taste Neurological 1.05 0.961 – 1.14 0.293 558 5576 all phecode
351 Other peripheral nerve disorders Neurological 0.992 0.967 – 1.02 0.54 7401 34460 all phecode
352 Disorders of other cranial nerves Neurological 0.971 0.923 – 1.02 0.249 1714 17106 all phecode
352.1 Trigeminal nerve disorders [CN5] Neurological 0.891 0.814 – 0.975 0.0118 535 5344 all phecode
352.2 Facial nerve disorders [CN7] Neurological 0.988 0.917 – 1.06 0.745 783 7826 all phecode
353 Nerve root and plexus disorders Neurological 1.01 0.975 – 1.04 0.654 4256 33369 all phecode
353.1 Nerve plexus lesions Neurological 0.988 0.891 – 1.1 0.826 390 3900 all phecode
353.2 Nerve root lesions Neurological 0.937 0.786 – 1.12 0.472 130 1287 all phecode
355 Complex regional/central pain syndrome Neurological 0.912 0.833 – 0.998 0.0456 531 5295 all phecode
355.1 Chronic pain syndrome Neurological 0.995 0.926 – 1.07 0.896 843 8386 all phecode
356 Hereditary and idiopathic peripheral neuropathy Neurological 0.978 0.937 – 1.02 0.319 2335 20731 all phecode
357 Inflammatory and toxic neuropathy Neurological 0.992 0.958 – 1.03 0.676 3472 29956 all phecode
358 Myoneural disorders Neurological 1.02 0.956 – 1.08 0.604 1147 11391 all phecode
358.1 Myasthenia gravis Neurological 1.03 0.835 – 1.27 0.777 109 1082 all phecode
359 Muscular dystrophies and other myopathies Neurological 0.959 0.902 – 1.02 0.177 1134 11274 all phecode
359.1 Muscular dystrophies Neurological 0.868 0.673 – 1.12 0.275 64 632 all phecode
359.2 Myopathy Neurological 0.956 0.899 – 1.02 0.158 1092 10843 all phecode
360 Disorders of the globe Sense Organs 0.983 0.824 – 1.17 0.846 131 1276 all phecode
360.2 Progressive myopia Sense Organs 1.02 0.792 – 1.31 0.886 65 640 all phecode
361 Retinal detachments and defects Sense Organs 0.935 0.867 – 1.01 0.0841 733 7131 all phecode
361.1 Retinal detachment with retinal defect Sense Organs 0.957 0.853 – 1.07 0.46 302 2962 all phecode
362 Other retinal disorders Sense Organs 1.02 0.988 – 1.06 0.187 3569 22997 all phecode
362.2
Degeneration of macula and posterior pole of
Degeneration of macula and posterior pole of retina
 Sense Organs 1.06 1.01 – 1.1 0.0209 2172 15483 all phecode
362.21 Macular degeneration, dry Sense Organs 1.02 0.921 – 1.12 0.735 419 3438 all phecode
362.22 Macular degeneration, wet Sense Organs 0.956 0.806 – 1.13 0.61 148 1184 all phecode
362.23 Cystoid macular degeneration of retina Sense Organs 1.06 0.956 – 1.17 0.275 408 3839 all phecode
362.26 Macular puckering of retina Sense Organs 1.06 0.991 – 1.13 0.0893 976 8610 all phecode
362.27 Drusen (degenerative) of retina Sense Organs 1.06 0.964 – 1.16 0.232 488 4558 all phecode
362.29 Macular degeneration (senile) of retina NOS Sense Organs 1.04 0.994 – 1.1 0.0842 1883 13955 all phecode
362.3 Other nondiabetic retinopathy Sense Organs 0.969 0.907 – 1.04 0.351 976 8527 all phecode
362.31 Separation of retinal layers Sense Organs 0.995 0.9 – 1.1 0.918 413 4056 all phecode
362.4 Retinal vascular changes and abnomalities Sense Organs 0.983 0.907 – 1.06 0.668 662 5933 all phecode
362.6 Peripheral retinal degenerations Sense Organs 1.03 0.931 – 1.14 0.551 392 3787 all phecode
362.7 Hereditary retinal dystrophies Sense Organs 1 0.867 – 1.15 0.999 215 2103 all phecode
362.8 Retinal hemorrhage/ischemia Sense Organs 0.881 0.772 – 1 0.0579 241 2368 all phecode
362.9 Retinal edema Sense Organs 0.906 0.807 – 1.02 0.0986 324 2936 all phecode
363
Chorioretinal inflammations, scars, and other
Chorioretinal inflammations, scars, and other disorders of choroid
 Sense Organs 1.02 0.926 – 1.12 0.723 492 4746 all phecode
363.3 Chorioretinal scars Sense Organs 1.02 0.913 – 1.14 0.699 332 3184 all phecode
364 Corneal opacity and other disorders of cornea Sense Organs 1.03 0.966 – 1.09 0.387 1132 10772 all phecode
364.1 Corneal opacity Sense Organs 0.909 0.818 – 1.01 0.0755 394 3846 all phecode
364.2 Corneal edema Sense Organs 0.917 0.757 – 1.11 0.379 123 1208 all phecode
364.4 Corneal degenerations Sense Organs 0.95 0.857 – 1.05 0.337 402 3962 all phecode
364.41 Keratoconus Sense Organs 1.04 0.817 – 1.32 0.751 75 739 all phecode
364.5 Corneal dystrophy Sense Organs 1.14 1.04 – 1.25 0.00586 502 4682 all phecode
364.51 Fuchs' dystrophy Sense Organs 1.08 0.949 – 1.23 0.246 266 2521 all phecode
364.9 Cornea replaced by transplant Sense Organs 1.11 0.891 – 1.38 0.358 91 885 all phecode
365 Glaucoma Sense Organs 0.992 0.953 – 1.03 0.701 2672 21326 all phecode
365.1 Open-angle glaucoma Sense Organs 0.984 0.91 – 1.06 0.68 705 6491 all phecode
365.11 Primary open angle glaucoma Sense Organs 1.01 0.915 – 1.12 0.791 403 3681 all phecode
365.2 Primary angle-closure glaucoma Sense Organs 1.02 0.891 – 1.16 0.81 251 2370 all phecode
366 Cataract Sense Organs 1.02 0.99 – 1.04 0.215 8611 28043 all phecode
366.1 Nonsenile Cataract Sense Organs 1.02 0.881 – 1.17 0.816 207 1979 all phecode
366.2 Senile cataract Sense Organs 1.03 1 – 1.07 0.0407 5480 24980 all phecode
367
Disorders of refraction and accommodation
Disorders of refraction and accommodation; blindness and low vision
 Sense Organs 1.01 0.985 – 1.03 0.48 8967 37779 all phecode
367.1 Myopia Sense Organs 1.01 0.977 – 1.04 0.625 5014 34677 all phecode
367.2 Astigmatism Sense Organs 1.03 0.994 – 1.06 0.104 4161 32463 all phecode
367.8 Hypermetropia Sense Organs 1.05 0.998 – 1.09 0.0612 2039 18599 all phecode
367.9 Blindness and low vision Sense Organs 0.953 0.899 – 1.01 0.107 1277 12356 all phecode
368 Visual disturbances Sense Organs 1.02 0.996 – 1.05 0.0866 5715 39599 all phecode
368.1 Amblyopia Sense Organs 1.07 0.988 – 1.16 0.0965 651 6479 all phecode
368.2 Diplopia and disorders of binocular vision Sense Organs 0.968 0.909 – 1.03 0.309 1087 10786 all phecode
368.3 Anisometropia Sense Organs 0.914 0.798 – 1.05 0.196 219 2168 all phecode
368.4 Visual field defects Sense Organs 0.982 0.924 – 1.04 0.555 1132 11173 all phecode
368.9 Subjective visual disturbances Sense Organs 1 0.94 – 1.07 0.953 1070 10620 all phecode
368.91 Psychophysical visual disturbances Sense Organs 0.842 0.699 – 1.02 0.0718 120 1171 all phecode
369 Infection of the eye Sense Organs 0.992 0.956 – 1.03 0.69 3185 28240 all phecode
369.2 Eye infection, viral Sense Organs 0.997 0.909 – 1.09 0.951 502 4954 all phecode
369.5 Conjunctivitis, infectious Sense Organs 0.991 0.952 – 1.03 0.641 2716 24970 all phecode
370 Keratitis Sense Organs 0.974 0.921 – 1.03 0.359 1365 13169 all phecode
370.1 Corneal ulcer Sense Organs 1.08 0.936 – 1.24 0.302 223 2194 all phecode
370.2 Superficial keratitis Sense Organs 0.948 0.867 – 1.04 0.237 546 5393 all phecode
370.3 Keratoconjunctivitis Sense Organs 0.945 0.871 – 1.03 0.179 649 6263 all phecode
370.31 Keratoconjunctivitis sicca Sense Organs 0.969 0.832 – 1.13 0.679 179 1677 all phecode
371 Inflammation of the eye Sense Organs 1.02 0.984 – 1.05 0.323 4414 32310 all phecode
371.1 Uveitis, noninfectious or NOS Sense Organs 1 0.916 – 1.09 0.999 541 5278 all phecode
371.2 Conjunctivitis, noninfectious Sense Organs 1.01 0.943 – 1.08 0.763 906 8939 all phecode
371.21 Allergic conjunctivitis Sense Organs 1.01 0.936 – 1.09 0.815 756 7515 all phecode
371.3 Inflammation of eyelids Sense Organs 1.02 0.98 – 1.05 0.398 3398 26983 all phecode
371.33 Noninfectious dermatoses of eyelid Sense Organs 1.02 0.858 – 1.22 0.808 133 1291 all phecode
372 Disorders of conjunctiva Sense Organs 1.09 1.02 – 1.16 0.0108 1118 10728 all phecode
374 Other disorders of eyelids Sense Organs 1 0.964 – 1.04 0.903 2940 24188 all phecode
374.1 Ectropion or entropion Sense Organs 0.948 0.859 – 1.05 0.297 431 4084 all phecode
374.2 Lagophthalmos Sense Organs 0.952 0.829 – 1.09 0.491 235 2335 all phecode
374.3 Ptosis of eyelid Sense Organs 0.966 0.908 – 1.03 0.284 1102 10734 all phecode
374.6 Dermatochalasis Sense Organs 1.01 0.943 – 1.07 0.863 1040 9720 all phecode
375 Disorders of lacrimal system Sense Organs 0.974 0.94 – 1.01 0.141 3694 26045 all phecode
375.1 Dry eyes Sense Organs 0.995 0.962 – 1.03 0.785 4040 26751 all phecode
375.2 Epiphora Sense Organs 0.889 0.804 – 0.983 0.0216 442 4354 all phecode
376 Disorders of the orbit Sense Organs 0.993 0.889 – 1.11 0.907 352 3508 all phecode
377 Disorders of optic nerve and visual pathways Sense Organs 1.03 0.963 – 1.1 0.382 913 9021 all phecode
377.1 Optic atrophy Sense Organs 0.988 0.876 – 1.11 0.846 283 2793 all phecode
377.3 Optic neuritis/neuropathy Sense Organs 1.04 0.956 – 1.13 0.359 585 5775 all phecode
378
Strabismus and other disorders of binocular eye
Strabismus and other disorders of binocular eye movements
 Sense Organs 0.998 0.941 – 1.06 0.936 1275 12460 all phecode
378.1 Strabismus (not specified as paralytic) Sense Organs 0.987 0.918 – 1.06 0.711 828 8130 all phecode
378.2 Nystagmus and other irregular eye movements Sense Organs 0.982 0.84 – 1.15 0.825 170 1686 all phecode
378.5 Paralytic strabismus Sense Organs 0.98 0.877 – 1.1 0.727 349 3437 all phecode
379 Other disorders of eye Sense Organs 1.03 1 – 1.06 0.0538 5046 29999 all phecode
379.1 Scleritis and episcleritis Sense Organs 0.88 0.752 – 1.03 0.114 176 1743 all phecode
379.2 Disorders of vitreous body Sense Organs 1.05 1.01 – 1.09 0.012 3634 23186 all phecode
379.3 Aphakia and other disorders of lens Sense Organs 0.849 0.709 – 1.02 0.0748 135 1258 all phecode
379.4 Anomalies of pupillary function Sense Organs 1.04 0.919 – 1.17 0.545 287 2833 all phecode
379.5 Disorders of iris and ciliary body Sense Organs 0.984 0.871 – 1.11 0.799 304 2948 all phecode
379.51 Pigmentary iris degeneration Sense Organs 1.05 0.827 – 1.34 0.685 77 731 all phecode
379.9 Pain, swelling or discharge of eye Sense Organs 0.964 0.907 – 1.03 0.246 1129 11130 all phecode
380 Disorders of external ear Sense Organs 1.04 0.991 – 1.08 0.119 2242 20393 all phecode
380.1 Otitis externa Sense Organs 1.02 0.965 – 1.08 0.511 1469 14580 all phecode
380.4 Impacted cerumen Sense Organs 1.05 1.01 – 1.1 0.0138 2648 23557 all phecode
381 Otitis media and Eustachian tube disorders Sense Organs 0.98 0.949 – 1.01 0.222 4255 36417 all phecode
381.1 Otitis media Sense Organs 0.978 0.942 – 1.02 0.255 3079 29813 all phecode
381.11 Suppurative and unspecified otitis media Sense Organs 0.974 0.936 – 1.01 0.21 2610 25602 all phecode
381.2 Eustachian tube disorders Sense Organs 0.977 0.93 – 1.03 0.344 1816 17827 all phecode
381.3 Mastoiditis & related conditions Sense Organs 1.03 0.871 – 1.22 0.734 153 1530 all phecode
381.9 Otorrhea Sense Organs 0.964 0.865 – 1.07 0.505 372 3713 all phecode
382 Otalgia Sense Organs 0.994 0.948 – 1.04 0.805 1884 18673 all phecode
383 Otosclerosis Sense Organs 1.02 0.847 – 1.22 0.858 124 1240 all phecode
384 Other disorders of tympanic membrane Sense Organs 0.97 0.886 – 1.06 0.514 516 5156 all phecode
384.1 Myringitis Sense Organs 0.814 0.616 – 1.08 0.148 51 502 all phecode
384.4 Perforation of tympanic membrane Sense Organs 0.968 0.873 – 1.07 0.538 403 4029 all phecode
385 Other disorders of middle ear and mastoid Sense Organs 0.975 0.882 – 1.08 0.614 432 4320 all phecode
385.3 Cholesteatoma Sense Organs 0.962 0.851 – 1.09 0.543 277 2770 all phecode
385.5
Tympanosclerosis and middle ear disease related
Tympanosclerosis and middle ear disease related to otitis media
 Sense Organs 0.88 0.73 – 1.06 0.181 118 1180 all phecode
386
Vertiginous syndromes and other disorders of
Vertiginous syndromes and other disorders of vestibular system
 Sense Organs 1.04 0.992 – 1.09 0.102 1882 18186 all phecode
386.1 Meniere's disease Sense Organs 1.05 0.931 – 1.17 0.456 319 3156 all phecode
386.2 Peripheral or central vertigo Sense Organs 1.05 0.993 – 1.1 0.093 1586 15423 all phecode
386.21 Central origin vertigo Sense Organs 1.05 0.992 – 1.12 0.0869 1208 11844 all phecode
386.3 Labyrinthitis Sense Organs 1.05 0.993 – 1.11 0.0902 1482 14530 all phecode
386.9
Dizziness and giddiness (Light-headedness and
Dizziness and giddiness (Light-headedness and vertigo)
 Sense Organs 1.02 0.997 – 1.05 0.0831 6933 38286 all phecode
388 Other disorders of ear Sense Organs 1.06 0.99 – 1.13 0.095 960 9501 all phecode
389 Hearing loss Sense Organs 1.01 0.987 – 1.04 0.361 8182 38069 all phecode
389.1 Sensorineural hearing loss Sense Organs 1.01 0.981 – 1.05 0.393 4107 29258 all phecode
389.2 Conductive hearing loss Sense Organs 0.932 0.87 – 0.998 0.0432 905 9042 all phecode
389.3 Degenerative and vascular disorders of ear Sense Organs 0.992 0.852 – 1.16 0.919 192 1808 all phecode
389.4 Tinnitus Sense Organs 1.04 0.992 – 1.08 0.107 2291 22130 all phecode
389.5 Disorders of acoustic nerve Sense Organs 1.03 0.853 – 1.24 0.78 124 1229 all phecode
394 Rheumatic disease of the heart valves Circulatory System 1.03 0.973 – 1.08 0.334 1458 13732 all phecode
394.1 Mitral valve stenosis and aortic valve stenosis Circulatory System 1.07 0.956 – 1.2 0.238 350 3415 all phecode
394.2 Mitral valve disease Circulatory System 1.03 0.932 – 1.13 0.598 462 4560 all phecode
394.3 Aortic valve disease Circulatory System 1.05 0.895 – 1.22 0.571 176 1691 all phecode
394.4 Acute rheumatic heart disease Circulatory System 0.823 0.626 – 1.08 0.162 55 546 all phecode
394.7 Disease of tricuspid valve Circulatory System 1.02 0.931 – 1.11 0.732 587 5739 all phecode
395 Heart valve disorders Circulatory System 1.05 1.01 – 1.08 0.00607 3976 28748 all phecode
395.1 Nonrheumatic mitral valve disorders Circulatory System 1.04 0.994 – 1.09 0.0869 2175 20441 all phecode
395.2 Nonrheumatic aortic valve disorders Circulatory System 1.07 1.02 – 1.12 0.00517 2060 17194 all phecode
395.3 Nonrheumatic tricuspid valve disorders Circulatory System 1.04 0.95 – 1.15 0.376 493 4864 all phecode
395.4 Nonrheumatic pulmonary valve disorders Circulatory System 0.949 0.776 – 1.16 0.606 108 1080 all phecode
395.6 Heart valve replaced Circulatory System 1.04 0.983 – 1.11 0.155 1177 10833 all phecode
396 Abnormal heart sounds Circulatory System 1.03 0.997 – 1.06 0.074 4718 34395 all phecode
401 Hypertension Circulatory System 0.989 0.969 – 1.01 0.315 23317 23367 all phecode
401.1 Essential hypertension Circulatory System 0.989 0.968 – 1.01 0.283 23158 23364 all phecode
401.2 Hypertensive heart and/or renal disease Circulatory System 1 0.962 – 1.04 0.979 3503 14616 all phecode
401.21 Hypertensive heart disease Circulatory System 1.08 1.01 – 1.16 0.0352 893 6607 all phecode
401.22 Hypertensive chronic kidney disease Circulatory System 0.98 0.937 – 1.02 0.367 2584 13072 all phecode
401.3 Other hypertensive complications Circulatory System 1.03 0.991 – 1.08 0.123 2679 15833 all phecode
411 Ischemic Heart Disease Circulatory System 1.07 1.04 – 1.1 1.54e-07 8807 30299 all phecode
411.1 Unstable angina (intermediate coronary syndrome) Circulatory System 1.15 1.07 – 1.23 9.27e-05 937 8574 all phecode
411.2 Myocardial infarction Circulatory System 1.08 1.04 – 1.12 1.64e-05 3594 21716 all phecode
411.3 Angina pectoris Circulatory System 1.08 1.03 – 1.13 0.000391 2485 18304 all phecode
411.4 Coronary atherosclerosis Circulatory System 1.08 1.06 – 1.11 5.23e-09 7555 27492 all phecode
411.41 Aneurysm and dissection of heart Circulatory System 1.11 0.94 – 1.32 0.214 156 1529 all phecode
411.8
Other chronic ischemic heart disease
Other chronic ischemic heart disease, unspecified
 Circulatory System 1.09 1.06 – 1.12 2.58e-09 6331 25741 all phecode
411.9
Other acute and subacute forms of ischemic
Other acute and subacute forms of ischemic heart disease
 Circulatory System 1.06 0.964 – 1.17 0.22 442 4211 all phecode
414 Other forms of chronic heart disease Circulatory System 1.11 1.07 – 1.16 2.38e-08 3101 22616 all phecode
414.2 ASCVD Circulatory System 1.13 1.05 – 1.22 0.00155 718 6816 all phecode
415 Pulmonary heart disease Circulatory System 1.02 0.982 – 1.05 0.342 3366 30208 all phecode
415.1 Acute pulmonary heart disease Circulatory System 1.03 0.982 – 1.08 0.231 1912 19014 all phecode
415.11 Pulmonary embolism and infarction, acute Circulatory System 1.03 0.98 – 1.08 0.26 1906 18953 all phecode
415.2 Chronic pulmonary heart disease Circulatory System 1.02 0.974 – 1.07 0.364 1808 17605 all phecode
415.21 Primary pulmonary hypertension Circulatory System 1 0.928 – 1.09 0.925 706 7032 all phecode
416 Cardiomegaly Circulatory System 0.946 0.892 – 1 0.0589 1254 12372 all phecode
418 Nonspecific chest pain Circulatory System 1.03 1 – 1.05 0.0177 12650 33952 all phecode
418.1 Precordial pain Circulatory System 1.07 1.01 – 1.13 0.0173 1471 13782 all phecode
420 Carditis Circulatory System 1.02 0.972 – 1.08 0.374 1588 15680 all phecode
420.1 Myocarditis Circulatory System 0.938 0.763 – 1.15 0.547 97 958 all phecode
420.2 Pericarditis Circulatory System 1.01 0.945 – 1.09 0.683 842 8402 all phecode
420.21 Acute pericarditis Circulatory System 0.989 0.85 – 1.15 0.882 177 1764 all phecode
420.22 Chronic pericarditis Circulatory System 1.04 0.856 – 1.25 0.714 117 1153 all phecode
420.3 Endocarditis Circulatory System 1.01 0.936 – 1.08 0.844 764 7535 all phecode
425 Cardiomyopathy Circulatory System 1.04 0.998 – 1.09 0.0588 2078 19881 all phecode
425.1 Primary/intrinsic cardiomyopathies Circulatory System 1.03 0.987 – 1.08 0.162 1989 19025 all phecode
425.11 Hypertrophic obstructive cardiomyopathy Circulatory System 0.977 0.848 – 1.13 0.744 208 2050 all phecode
425.12 Other hypertrophic cardiomyopathy Circulatory System 1.02 0.881 – 1.18 0.802 201 1992 all phecode
425.2 Secondary/extrinsic cardiomyopathies Circulatory System 1.01 0.897 – 1.13 0.931 317 3170 all phecode
425.8 Other cardiomyopathy Circulatory System 1.04 0.845 – 1.29 0.692 95 931 all phecode
426 Cardiac conduction disorders Circulatory System 1.02 0.998 – 1.04 0.0794 12327 25440 all phecode
426.2 Atrioventricular [AV] block Circulatory System 1.04 0.991 – 1.1 0.109 1903 11501 all phecode
426.21 First degree AV block Circulatory System 1.03 0.97 – 1.09 0.347 1313 8899 all phecode
426.22 Mobitz II AV block Circulatory System 1.2 0.938 – 1.52 0.149 64 553 all phecode
426.23 Second degree AV block Circulatory System 1.04 0.91 – 1.2 0.538 216 1925 all phecode
426.24 Atrioventricular block, complete Circulatory System 1.1 0.999 – 1.21 0.0525 461 3823 all phecode
426.25 Other heart block Circulatory System 1.11 0.96 – 1.29 0.155 203 1803 all phecode
426.3 Bundle branch block Circulatory System 1.06 1.01 – 1.11 0.00977 2306 13999 all phecode
426.31 Right bundle branch block Circulatory System 1.05 0.994 – 1.11 0.0794 1423 10758 all phecode
426.32 Left bundle branch block Circulatory System 1.06 0.993 – 1.13 0.0815 969 8110 all phecode
426.4 Anomalous atrioventricular excitation Circulatory System 0.977 0.775 – 1.23 0.841 82 820 all phecode
426.7 Abnormal electrocardiogram [ECG] [EKG] Circulatory System 1.02 0.994 – 1.04 0.151 10577 25186 all phecode
426.8 Other cardiac conduction disorders Circulatory System 1.01 0.936 – 1.1 0.742 679 6650 all phecode
426.9 Cardiac pacemaker/device in situ Circulatory System 1.04 0.984 – 1.09 0.184 1754 11536 all phecode
426.91 Cardiac pacemaker in situ Circulatory System 1.02 0.957 – 1.08 0.582 1171 8184 all phecode
426.92 Cardiac defibrillator in situ Circulatory System 1.08 1.01 – 1.16 0.0352 846 7320 all phecode
427 Cardiac dysrhythmias Circulatory System 1.01 0.987 – 1.03 0.488 17397 25735 all phecode
427.1 Paroxysmal tachycardia, unspecified Circulatory System 1.03 0.985 – 1.07 0.202 2474 18178 all phecode
427.11 Paroxysmal supraventricular tachycardia Circulatory System 1.01 0.963 – 1.07 0.58 1595 14293 all phecode
427.12 Paroxysmal ventricular tachycardia Circulatory System 1.06 0.997 – 1.13 0.0629 1181 9915 all phecode
427.2 Atrial fibrillation and flutter Circulatory System 1.01 0.974 – 1.04 0.677 5313 18688 all phecode
427.21 Atrial fibrillation Circulatory System 1.01 0.973 – 1.04 0.716 5188 18409 all phecode
427.22 Atrial flutter Circulatory System 1.02 0.972 – 1.08 0.38 1693 11042 all phecode
427.3 Other specified cardiac dysrhythmias Circulatory System 1.02 0.99 – 1.04 0.241 8688 25552 all phecode
427.4 Cardiac arrest and ventricular fibrillation Circulatory System 0.994 0.909 – 1.09 0.892 536 5233 all phecode
427.41 Ventricular fibrillation and flutter Circulatory System 1.09 0.947 – 1.26 0.23 216 2118 all phecode
427.42 Cardiac arrest Circulatory System 0.992 0.896 – 1.1 0.878 410 4034 all phecode
427.5 Arrhythmia (cardiac) NOS Circulatory System 1 0.975 – 1.03 0.841 6905 25457 all phecode
427.6 Premature beats Circulatory System 1.07 1.02 – 1.11 0.00471 2359 16248 all phecode
427.61 Supraventricular premature beats Circulatory System 1.03 0.952 – 1.12 0.438 670 6287 all phecode
427.7 Tachycardia NOS Circulatory System 1.02 0.986 – 1.05 0.281 5124 25531 all phecode
427.8 Sinoatrial node dysfunction (Bradycardia) Circulatory System 1.01 0.944 – 1.08 0.74 912 7501 all phecode
427.9 Palpitations Circulatory System 1.02 0.984 – 1.05 0.326 4430 24505 all phecode
428 Congestive heart failure; nonhypertensive Circulatory System 1.03 0.998 – 1.07 0.0668 4300 23663 all phecode
428.1 Congestive heart failure (CHF) NOS Circulatory System 1.03 0.997 – 1.07 0.0691 3756 22446 all phecode
428.2 Heart failure NOS Circulatory System 1.02 0.986 – 1.06 0.247 3701 21722 all phecode
428.3
Heart failure with reduced EF [Systolic or
Heart failure with reduced EF [Systolic or combined heart failure]
 Circulatory System 1.04 0.991 – 1.09 0.107 1765 14476 all phecode
428.4
Heart failure with preserved EF [Diastolic
Heart failure with preserved EF [Diastolic heart failure]
 Circulatory System 1 0.95 – 1.05 0.988 1648 13395 all phecode
429
Ill-defined descriptions and complications of
Ill-defined descriptions and complications of heart disease
 Circulatory System 1.03 1.01 – 1.05 0.0141 12635 32504 all phecode
429.1 Heart transplant/surgery Circulatory System 1.04 0.982 – 1.11 0.17 1219 11696 all phecode
429.2 Abnormal function study of cardiovascular system Circulatory System 1.04 1.01 – 1.07 0.0118 6322 29232 all phecode
429.3 Symptoms involving cardiovascular system Circulatory System 1.02 1 – 1.05 0.0398 9650 32421 all phecode
429.9 Cardiac complications, not elsewhere classified Circulatory System 1.05 0.972 – 1.13 0.221 723 7072 all phecode
430 Intracranial hemorrhage Circulatory System 0.981 0.912 – 1.06 0.612 789 7842 all phecode
430.1 Subarachnoid hemorrhage Circulatory System 0.97 0.854 – 1.1 0.633 261 2610 all phecode
430.2 Intracerebral hemorrhage Circulatory System 0.947 0.852 – 1.05 0.32 368 3671 all phecode
430.3 Subdural hemorrhage Circulatory System 0.983 0.87 – 1.11 0.785 272 2680 all phecode
433 Cerebrovascular disease Circulatory System 1.03 1 – 1.06 0.0283 5463 32242 all phecode
433.1 Occlusion and stenosis of precerebral arteries Circulatory System 1.09 1.04 – 1.14 0.000615 1978 16212 all phecode
433.11
Occlusion of cerebral arteries, with cerebral
Occlusion of cerebral arteries, with cerebral infarction
 Circulatory System 1.15 1.02 – 1.31 0.0253 260 2517 all phecode
433.12 Cerebral atherosclerosis Circulatory System 1.21 0.964 – 1.53 0.0995 80 789 all phecode
433.2 Occlusion of cerebral arteries Circulatory System 1.01 0.969 – 1.05 0.62 2437 21732 all phecode
433.21
Cerebral artery occlusion, with cerebral
Cerebral artery occlusion, with cerebral infarction
 Circulatory System 1.01 0.967 – 1.05 0.684 2357 21103 all phecode
433.3 Cerebral ischemia Circulatory System 1.03 0.993 – 1.07 0.107 2780 22868 all phecode
433.31 Transient cerebral ischemia Circulatory System 1.03 0.987 – 1.07 0.171 2409 20762 all phecode
433.5 Cerebral aneurysm Circulatory System 0.972 0.885 – 1.07 0.55 474 4724 all phecode
433.6 Acute, but ill-defined cerebrovascular disease Circulatory System 1.05 0.956 – 1.16 0.299 464 4518 all phecode
433.8 Late effects of cerebrovascular disease Circulatory System 0.993 0.919 – 1.07 0.867 695 6822 all phecode
440 Atherosclerosis Circulatory System 1.07 1.02 – 1.11 0.00292 2477 19724 all phecode
440.1 Atherosclerosis of renal artery Circulatory System 1.05 0.922 – 1.21 0.439 231 2291 all phecode
440.2 Atherosclerosis of the extremities Circulatory System 1.05 0.996 – 1.11 0.071 1516 13532 all phecode
440.21
Atherosclerosis of native arteries of the
Atherosclerosis of native arteries of the extremities with ulceration or gangrene
 Circulatory System 1.03 0.909 – 1.17 0.631 274 2669 all phecode
440.22
Atherosclerosis of native arteries of the
Atherosclerosis of native arteries of the extremities with intermittent claudication
 Circulatory System 1.07 1 – 1.14 0.0452 1040 9647 all phecode
440.9 Atherosclerosis of aorta Circulatory System 1.13 1.05 – 1.21 0.000913 846 8124 all phecode
441 Vascular insufficiency of intestine Circulatory System 0.989 0.903 – 1.08 0.816 515 5115 all phecode
441.1 Acute vascular insufficiency of intestine Circulatory System 0.995 0.87 – 1.14 0.94 240 2387 all phecode
441.2 Chronic vascular insufficiency of intestine Circulatory System 1.03 0.876 – 1.22 0.687 154 1536 all phecode
442 Other aneurysm Circulatory System 1.02 0.981 – 1.06 0.3 2779 21466 all phecode
442.1 Aortic aneurysm Circulatory System 1.04 0.991 – 1.09 0.119 2054 16492 all phecode
442.11 Abdominal aortic aneurysm Circulatory System 1.07 1.01 – 1.13 0.0286 1189 10558 all phecode
442.2 Aneurysm of iliac artery Circulatory System 1.05 0.912 – 1.22 0.485 202 2002 all phecode
442.3 Aneurysm of artery of lower extremity Circulatory System 0.987 0.848 – 1.15 0.869 179 1765 all phecode
442.4 Arterial dissection Circulatory System 0.892 0.769 – 1.03 0.13 184 1840 all phecode
442.8 Aneurysm of other specified artery Circulatory System 1.01 0.907 – 1.11 0.923 399 3978 all phecode
443 Peripheral vascular disease Circulatory System 1.04 1 – 1.08 0.0424 3086 24814 all phecode
443.1 Raynaud's syndrome Circulatory System 1.01 0.938 – 1.09 0.744 742 7390 all phecode
443.7
Peripheral angiopathy in diseases classified
Peripheral angiopathy in diseases classified elsewhere
 Circulatory System 1.07 0.927 – 1.22 0.371 220 2087 all phecode
443.8 Other specified peripheral vascular diseases Circulatory System 1.04 0.995 – 1.08 0.0882 2557 21985 all phecode
443.9 Peripheral vascular disease, unspecified Circulatory System 1.05 1 – 1.09 0.038 2341 18862 all phecode
444 Arterial embolism and thrombosis Circulatory System 1.03 0.955 – 1.1 0.484 848 8423 all phecode
444.1
Arterial embolism and thrombosis of lower
Arterial embolism and thrombosis of lower extremity artery
 Circulatory System 0.99 0.88 – 1.11 0.87 313 3099 all phecode
444.2 Embolism and thrombosis of abdominal aorta Circulatory System 1.14 0.966 – 1.35 0.119 155 1548 all phecode
446 Polyarteritis nodosa and allied conditions Circulatory System 1.03 0.934 – 1.13 0.57 460 4559 all phecode
446.4 Wegener's granulomatosis Circulatory System 1.03 0.854 – 1.25 0.731 109 1075 all phecode
446.5 Giant cell arteritis Circulatory System 1.07 0.851 – 1.34 0.565 79 749 all phecode
446.9 Arteritis NOS Circulatory System 0.971 0.861 – 1.1 0.63 289 2876 all phecode
447 Other disorders of arteries and arterioles Circulatory System 1.03 0.992 – 1.08 0.116 2647 22765 all phecode
447.1 Stricture of artery Circulatory System 1.08 0.983 – 1.18 0.115 523 5163 all phecode
447.7 Aortic ectasia Circulatory System 0.987 0.918 – 1.06 0.729 804 7938 all phecode
448 Disease of capillaries Circulatory System 1 0.944 – 1.06 0.962 1237 12127 all phecode
450 Noninfectious disorders of lymphatic channels Circulatory System 0.973 0.93 – 1.02 0.227 2104 20985 all phecode
451 Phlebitis and thrombophlebitis Circulatory System 0.966 0.895 – 1.04 0.37 738 7355 all phecode
451.2
Phlebitis and thrombophlebitis of lower
Phlebitis and thrombophlebitis of lower extremities
 Circulatory System 0.948 0.832 – 1.08 0.422 244 2437 all phecode
452 Other venous embolism and thrombosis Circulatory System 0.997 0.967 – 1.03 0.857 4957 29867 all phecode
452.1 Iatrogenic pulmonary embolism and infarction Circulatory System 1.01 0.894 – 1.15 0.827 276 2747 all phecode
452.2 Deep vein thrombosis [DVT] Circulatory System 0.987 0.952 – 1.02 0.495 3260 26940 all phecode
452.8 Postphlebitic syndrome Circulatory System 1.14 0.964 – 1.35 0.124 154 1529 all phecode
453 Chronic venous hypertension Circulatory System 0.991 0.864 – 1.14 0.901 220 2168 all phecode
454 Varicose veins Circulatory System 0.966 0.928 – 1 0.0809 2827 24555 all phecode
454.1 Varicose veins of lower extremity Circulatory System 0.97 0.931 – 1.01 0.162 2469 21426 all phecode
454.11 Varicose veins of lower extremity, symptomtic Circulatory System 0.962 0.913 – 1.01 0.151 1565 15056 all phecode
455 Hemorrhoids Circulatory System 1.05 1.02 – 1.08 0.00127 5799 29818 all phecode
456 Chronic venous insufficiency [CVI] Circulatory System 0.973 0.936 – 1.01 0.149 3097 24898 all phecode
457
Encounter for long-term (current) use of
Encounter for long-term (current) use of anticoagulants, antithrombotics, aspirin
 Circulatory System 1.08 1.03 – 1.13 0.00069 2095 15309 all phecode
457.2
Encounter for long-term (current) use of
Encounter for long-term (current) use of antiplatelets/antithrombotics
 Circulatory System 1.12 0.999 – 1.26 0.0518 324 3221 all phecode
457.3 Encounter for long-term (current) use of aspirin Circulatory System 1.08 1.03 – 1.14 0.00103 1973 14689 all phecode
458 Hypotension Circulatory System 1.01 0.98 – 1.04 0.52 5091 32185 all phecode
458.1 Orthostatic hypotension Circulatory System 0.969 0.916 – 1.03 0.28 1344 12938 all phecode
458.2 Iatrogenic hypotension Circulatory System 1.02 0.959 – 1.09 0.524 1109 11012 all phecode
458.9 Hypotension NOS Circulatory System 1.01 0.979 – 1.04 0.522 4618 31186 all phecode
459 Other disorders of circulatory system Circulatory System 1.01 0.99 – 1.04 0.251 7825 34792 all phecode
459.1 Hemorrhage NOS Circulatory System 1.02 0.947 – 1.09 0.638 834 8215 all phecode
459.7 Blood vessel replaced Circulatory System 1.01 0.95 – 1.07 0.835 1305 13023 all phecode
459.9 Circulatory disease NEC Circulatory System 1.02 0.993 – 1.05 0.155 6706 33592 all phecode
464 Acute sinusitis Respiratory 1 0.97 – 1.03 0.972 4792 32137 all phecode
465
Acute upper respiratory infections of multiple
Acute upper respiratory infections of multiple or unspecified sites
 Respiratory 1.01 0.987 – 1.03 0.414 9601 35915 all phecode
465.2 Acute pharyngitis Respiratory 1.01 0.979 – 1.04 0.559 5310 32365 all phecode
465.4 Acute laryngitis and tracheitis Respiratory 1.02 0.93 – 1.13 0.62 443 4428 all phecode
470 Septal Deviations/Turbinate Hypertrophy Respiratory 0.975 0.929 – 1.02 0.32 1797 17640 all phecode
471 Nasal polyps Respiratory 0.959 0.882 – 1.04 0.331 592 5881 all phecode
472 Chronic pharyngitis and nasopharyngitis Respiratory 0.967 0.921 – 1.02 0.185 1797 16986 all phecode
473 Diseases of the larynx and vocal cords Respiratory 0.992 0.955 – 1.03 0.669 2983 25244 all phecode
473.1 Chronic laryngitis Respiratory 1 0.79 – 1.27 0.992 68 674 all phecode
473.3 Paralysis/spasm of vocal cords or larynx Respiratory 1.11 1.02 – 1.21 0.0149 628 6254 all phecode
473.4 Voice disturbance Respiratory 1 0.959 – 1.05 0.939 2336 21975 all phecode
474 Acute and chronic tonsillitis Respiratory 1 0.936 – 1.08 0.904 880 7892 all phecode
474.1 Acute tonsillitis Respiratory 1.03 0.925 – 1.16 0.558 335 3181 all phecode
474.2 Chronic tonsillitis and adenoiditis Respiratory 1.01 0.934 – 1.09 0.81 700 6445 all phecode
475 Chronic sinusitis Respiratory 0.992 0.96 – 1.02 0.607 4378 27891 all phecode
475.9 Postnasal drip Respiratory 1.02 0.955 – 1.09 0.526 922 9017 all phecode
476 Allergic rhinitis Respiratory 0.99 0.97 – 1.01 0.377 12687 28117 all phecode
477 Epistaxis or throat hemorrhage Respiratory 1.08 1.02 – 1.15 0.0146 1150 11318 all phecode
478 Throat pain Respiratory 1.09 0.987 – 1.21 0.0886 426 4195 all phecode
479 Other upper respiratory disease Respiratory 1 0.974 – 1.03 0.876 5627 28048 all phecode
480 Pneumonia Respiratory 1.03 1.01 – 1.06 0.0198 5947 37034 all phecode
480.1 Bacterial pneumonia Respiratory 1.06 0.996 – 1.12 0.0688 1155 11495 all phecode
480.11 Pneumococcal pneumonia Respiratory 1.09 1 – 1.19 0.0477 568 5644 all phecode
480.12 Pseudomonal pneumonia Respiratory 0.997 0.849 – 1.17 0.971 153 1523 all phecode
480.13 MRSA pneumonia Respiratory 0.878 0.722 – 1.07 0.192 117 1165 all phecode
480.2 Viral pneumonia Respiratory 1.08 0.94 – 1.24 0.272 202 1992 all phecode
480.3 Pneumonia due to fungus (mycoses) Respiratory 1.05 0.893 – 1.23 0.566 159 1590 all phecode
480.5 Bronchopneumonia and lung abscess Respiratory 1.01 0.847 – 1.21 0.904 135 1312 all phecode
481 Influenza Respiratory 1.04 0.982 – 1.1 0.183 1355 13284 all phecode
483 Acute bronchitis and bronchiolitis Respiratory 1.01 0.972 – 1.04 0.683 3412 29871 all phecode
495 Asthma Respiratory 0.978 0.955 – 1 0.0652 8671 33569 all phecode
495.1 Chronic obstructive asthma Respiratory 1.02 0.921 – 1.13 0.695 397 3925 all phecode
495.11 Chronic obstructive asthma with exacerbation Respiratory 1.2 0.945 – 1.52 0.134 81 802 all phecode
495.2 Asthma with exacerbation Respiratory 0.998 0.948 – 1.05 0.939 1629 16033 all phecode
496 Chronic airway obstruction Respiratory 0.991 0.963 – 1.02 0.57 5343 28343 all phecode
496.1 Emphysema Respiratory 1.01 0.965 – 1.06 0.684 2134 19414 all phecode
496.2 Chronic bronchitis Respiratory 0.988 0.956 – 1.02 0.459 4128 26624 all phecode
496.21 Obstructive chronic bronchitis Respiratory 0.993 0.959 – 1.03 0.67 3747 25467 all phecode
496.3 Bronchiectasis Respiratory 1.01 0.927 – 1.11 0.772 549 5453 all phecode
497 Bronchitis Respiratory 1.01 0.96 – 1.05 0.808 1946 18824 all phecode
498 Acute bronchospasm Respiratory 0.946 0.863 – 1.04 0.241 496 4943 all phecode
499 Cystic fibrosis Respiratory 0.999 0.846 – 1.18 0.993 151 1510 all phecode
500 Lung disease due to external agents Respiratory 0.911 0.836 – 0.994 0.0356 557 5551 all phecode
500.1 Extrinsic allergic alveolitis Respiratory 0.865 0.699 – 1.07 0.182 92 920 all phecode
500.2 Pneumoconiosis Respiratory 0.957 0.767 – 1.19 0.699 78 764 all phecode
501 Pneumonitis due to inhalation of food or vomitus Respiratory 1.05 0.972 – 1.15 0.203 634 6225 all phecode
502 Postinflammatory pulmonary fibrosis Respiratory 0.992 0.922 – 1.07 0.838 815 8076 all phecode
503 Pulmonary congestion and hypostasis Respiratory 1.02 0.951 – 1.1 0.559 835 8243 all phecode
504 Other alveolar and parietoalveolar pneumonopathy Respiratory 0.996 0.914 – 1.08 0.921 595 5878 all phecode
504.1 Idiopathic fibrosing alveolitis Respiratory 1.08 0.956 – 1.21 0.225 311 3084 all phecode
505 Other pulmonary inflamation or edema Respiratory 1.02 0.972 – 1.08 0.381 1638 15749 all phecode
506 Empyema and pneumothorax Respiratory 1.04 0.996 – 1.08 0.0796 2894 25235 all phecode
507 Pleurisy; pleural effusion Respiratory 0.991 0.953 – 1.03 0.631 2916 26208 all phecode
508
Pulmonary collapse; interstitial and
Pulmonary collapse; interstitial and compensatory emphysema
 Respiratory 1.01 0.972 – 1.06 0.504 2382 22588 all phecode
509 Respiratory failure, insufficiency, arrest Respiratory 1.03 0.997 – 1.07 0.0719 4032 29477 all phecode
509.1 Respiratory failure Respiratory 1.02 0.971 – 1.07 0.459 1937 18949 all phecode
509.2 Respiratory insufficiency Respiratory 1.01 0.953 – 1.08 0.695 1174 11679 all phecode
509.3
Pulmonary insufficiency or respiratory failure
Pulmonary insufficiency or respiratory failure following trauma and surgery
 Respiratory 1.01 0.956 – 1.06 0.832 1689 16489 all phecode
509.8
Dependence on respirator [Ventilator] or
Dependence on respirator [Ventilator] or supplemental oxygen
 Respiratory 1.02 0.973 – 1.07 0.385 1741 17249 all phecode
510 Other diseases of lung Respiratory 1.02 0.989 – 1.05 0.234 5503 35907 all phecode
510.2 Lung transplant Respiratory 1.06 0.915 – 1.24 0.426 176 1757 all phecode
512 Other symptoms of respiratory system Respiratory 1.01 0.99 – 1.03 0.361 18621 28154 all phecode
512.1 Wheezing Respiratory 0.965 0.912 – 1.02 0.207 1409 13516 all phecode
512.2 Painful respiration Respiratory 1.01 0.967 – 1.05 0.653 2309 21263 all phecode
512.3 Abnormal chest sounds Respiratory 0.962 0.852 – 1.09 0.538 291 2845 all phecode
512.7 Shortness of breath Respiratory 1.02 0.998 – 1.05 0.0755 10034 28081 all phecode
512.8 Cough Respiratory 0.996 0.973 – 1.02 0.74 9501 28148 all phecode
512.9 Other dyspnea Respiratory 1.02 0.997 – 1.04 0.0894 10804 28104 all phecode
513 Respiratory abnormalities Respiratory 1.01 0.986 – 1.03 0.549 12932 33822 all phecode
513.3 Hypoventilation Respiratory 0.998 0.931 – 1.07 0.948 880 8646 all phecode
513.31 Apnea Respiratory 1.04 0.941 – 1.14 0.475 462 4607 all phecode
513.32 Orthopnea Respiratory 0.981 0.858 – 1.12 0.782 220 2160 all phecode
513.4 Hyperventilation Respiratory 1.05 0.962 – 1.15 0.258 515 5124 all phecode
513.8 Disorders of diaphragm Respiratory 1 0.879 – 1.14 0.997 258 2557 all phecode
514 Abnormal findings examination of lungs Respiratory 0.992 0.964 – 1.02 0.586 5365 34834 all phecode
514.1
Abnormal results of function study of pulmonary
Abnormal results of function study of pulmonary system
 Respiratory 1.02 0.895 – 1.15 0.809 258 2580 all phecode
514.2 Solitary pulmonary nodule Respiratory 0.982 0.946 – 1.02 0.355 3018 27338 all phecode
516 Abnormal sputum Respiratory 1.01 0.938 – 1.1 0.728 735 7332 all phecode
516.1 Hemoptysis Respiratory 1.02 0.937 – 1.11 0.657 611 6080 all phecode
519
Other diseases of respiratory system, not
Other diseases of respiratory system, not elsewhere classified
 Respiratory 1.01 0.982 – 1.04 0.528 6458 39057 all phecode
519.1 Tracheostomy complications Respiratory 0.995 0.862 – 1.15 0.945 214 2136 all phecode
519.2 Respiratory complications Respiratory 0.996 0.903 – 1.1 0.928 445 4430 all phecode
519.8 Other diseases of respiratory system, NEC Respiratory 0.967 0.918 – 1.02 0.209 1588 15787 all phecode
519.9
Symptoms involving respiratory system and other
Symptoms involving respiratory system and other chest symptoms
 Respiratory 1.02 0.989 – 1.05 0.2 4706 34489 all phecode
520 Disorders of tooth development Digestive 0.983 0.883 – 1.09 0.756 369 3690 all phecode
520.1 Hereditary disturbances in tooth structure Digestive 0.947 0.807 – 1.11 0.507 165 1642 all phecode
520.2 Disturbances in tooth eruption Digestive 1.02 0.885 – 1.17 0.8 218 2172 all phecode
521 Diseases of hard tissues of teeth Digestive 0.949 0.885 – 1.02 0.137 898 8954 all phecode
521.1 Dental caries Digestive 0.942 0.877 – 1.01 0.103 837 8349 all phecode
521.2 Dental abrasion, erosion and attrition Digestive 0.997 0.752 – 1.32 0.985 52 510 all phecode
522 Diseases of pulp and periapical tissues Digestive 1.03 0.938 – 1.12 0.567 535 5340 all phecode
522.5 Periapical abscess Digestive 0.997 0.904 – 1.1 0.945 459 4583 all phecode
523 Gingival and periodontal diseases Digestive 0.975 0.903 – 1.05 0.524 718 7180 all phecode
523.1 Gingivitis Digestive 0.843 0.709 – 1 0.053 142 1418 all phecode
523.3 Periodontitis (acute or chronic) Digestive 0.997 0.896 – 1.11 0.962 364 3636 all phecode
523.31 Acute periodontitis Digestive 0.954 0.85 – 1.07 0.431 311 3109 all phecode
523.32 Chronic periodontitis Digestive 1.19 0.982 – 1.44 0.0757 122 1204 all phecode
524 Dentofacial anomalies, including malocclusion Digestive 0.999 0.896 – 1.11 0.992 363 3630 all phecode
524.3 Anomalies of tooth position/malocclusion Digestive 1.07 0.928 – 1.22 0.368 220 2200 all phecode
525
Other diseases of the teeth and supporting
Other diseases of the teeth and supporting structures
 Digestive 0.992 0.929 – 1.06 0.798 1039 10382 all phecode
525.1 Loss of teeth or edentulism Digestive 0.964 0.865 – 1.07 0.503 374 3731 all phecode
526 Diseases of the jaws Digestive 0.977 0.939 – 1.02 0.257 2680 26455 all phecode
526.1 Cysts of the jaws Digestive 0.977 0.856 – 1.11 0.728 247 2470 all phecode
526.3 Anomalies of jaw size/symmetry Digestive 0.933 0.817 – 1.06 0.299 241 2383 all phecode
526.4 Temporomandibular joint disorders Digestive 1 0.949 – 1.06 0.953 1504 15025 all phecode
526.41 Temporomandibular joint disorder, unspecified Digestive 1 0.942 – 1.06 0.999 1187 11858 all phecode
526.42 Arthralgia/ankylosis of temporomandibular joint Digestive 1.01 0.932 – 1.08 0.892 741 7400 all phecode
526.5 Inflammatory conditions of jaw Digestive 0.961 0.85 – 1.09 0.526 287 2864 all phecode
526.8 Exostosis of jaw Digestive 0.992 0.747 – 1.32 0.953 53 521 all phecode
526.9 Jaw disease NOS Digestive 0.964 0.878 – 1.06 0.438 487 4867 all phecode
527 Diseases of the salivary glands Digestive 0.982 0.935 – 1.03 0.469 1781 17771 all phecode
527.1 Hypertrophy of salivary gland Digestive 0.966 0.745 – 1.25 0.793 58 579 all phecode
527.2 Sialoadenitis Digestive 1 0.904 – 1.11 0.945 394 3936 all phecode
527.7 Disturbance of salivary secretion Digestive 0.999 0.934 – 1.07 0.969 952 9481 all phecode
527.8 Other specified diseases of the salivary glands Digestive 1.04 0.911 – 1.18 0.591 254 2540 all phecode
528
Diseases of the oral soft tissues, excluding
Diseases of the oral soft tissues, excluding lesions specific for gingiva and tongue
 Digestive 0.975 0.937 – 1.02 0.228 2643 26197 all phecode
528.1 Stomatitis and mucositis Digestive 0.926 0.855 – 1 0.0601 668 6657 all phecode
528.11 Stomatitis and mucositis (ulcerative) Digestive 0.861 0.748 – 0.99 0.0361 211 2110 all phecode
528.12 Oral aphthae Digestive 0.952 0.829 – 1.09 0.483 215 2137 all phecode
528.3 Cellulitis and abscess of oral soft tissues Digestive 0.936 0.82 – 1.07 0.329 235 2338 all phecode
528.4 Cysts of oral soft tissues Digestive 1.1 0.917 – 1.32 0.307 124 1229 all phecode
528.41 Cyst of the salivary gland Digestive 0.963 0.767 – 1.21 0.748 77 760 all phecode
528.5 Diseases of lips Digestive 0.977 0.886 – 1.08 0.632 462 4602 all phecode
528.6 Leukoplakia of oral mucosa Digestive 0.94 0.79 – 1.12 0.489 137 1370 all phecode
528.7 Sialolithiasis Digestive 1.08 0.915 – 1.27 0.374 163 1623 all phecode
529 Diseases and other conditions of the tongue Digestive 1.02 0.947 – 1.11 0.543 690 6878 all phecode
529.1 Glossitis Digestive 1.05 0.88 – 1.25 0.599 129 1281 all phecode
529.6 Glossodynia Digestive 0.919 0.783 – 1.08 0.3 168 1652 all phecode
530 Diseases of esophagus Digestive 0.991 0.972 – 1.01 0.368 17081 27931 all phecode
530.1 Esophagitis, GERD and related diseases Digestive 0.992 0.973 – 1.01 0.426 16572 27931 all phecode
530.11 GERD Digestive 0.991 0.971 – 1.01 0.366 16143 27929 all phecode
530.12 Ulcer of esophagus Digestive 1.04 0.939 – 1.16 0.433 400 3983 all phecode
530.13 Barrett's esophagus Digestive 0.987 0.916 – 1.06 0.742 762 7584 all phecode
530.14 Reflux esophagitis Digestive 0.981 0.936 – 1.03 0.443 1900 17495 all phecode
530.15 Eosinophilic esophagitis Digestive 0.811 0.705 – 0.933 0.00348 221 2210 all phecode
530.2 Esophageal bleeding (varices/hemorrhage) Digestive 0.916 0.845 – 0.994 0.0349 651 6473 all phecode
530.3 Stricture and stenosis of esophagus Digestive 0.987 0.922 – 1.06 0.712 911 8971 all phecode
530.5 Disorders of esophageal motility Digestive 1.03 0.942 – 1.12 0.523 548 5432 all phecode
530.6 Diverticulum of esophagus, acquired Digestive 1.05 0.874 – 1.25 0.616 129 1265 all phecode
530.7 Gastroesophageal laceration-hemorrhage syndrome Digestive 0.706 0.559 – 0.893 0.00363 82 812 all phecode
530.9 Heartburn Digestive 0.974 0.924 – 1.03 0.332 1519 14928 all phecode
531 Peptic ulcer (excl. esophageal) Digestive 0.984 0.941 – 1.03 0.496 2073 20617 all phecode
531.1 Hemorrhage from gastrointestinal ulcer Digestive 1.01 0.909 – 1.12 0.893 391 3883 all phecode
531.2 Gastric ulcer Digestive 0.98 0.922 – 1.04 0.504 1201 11970 all phecode
531.3 Duodenal ulcer Digestive 0.957 0.87 – 1.05 0.36 467 4640 all phecode
531.4 Peptic ulcer, site unspecified Digestive 0.92 0.856 – 0.99 0.0248 804 8018 all phecode
531.5 Gastrojejunal ulcer Digestive 1.05 0.891 – 1.24 0.553 150 1500 all phecode
532 Dysphagia Digestive 0.982 0.954 – 1.01 0.234 5585 26852 all phecode
535 Gastritis and duodenitis Digestive 0.994 0.956 – 1.03 0.762 2799 27335 all phecode
535.1 Acute gastritis Digestive 0.994 0.936 – 1.06 0.852 1178 11750 all phecode
535.2 Atrophic gastritis Digestive 0.968 0.865 – 1.08 0.566 344 3413 all phecode
535.6 Duodenitis Digestive 0.94 0.841 – 1.05 0.271 334 3337 all phecode
535.8 Other specified gastritis Digestive 0.949 0.873 – 1.03 0.215 638 6354 all phecode
535.9 Gastritis and duodenitis, NOS Digestive 0.979 0.923 – 1.04 0.478 1255 12511 all phecode
536 Disorders of function of stomach Digestive 1.01 0.968 – 1.05 0.741 2911 27685 all phecode
536.3 Gastroparesis Digestive 1.04 0.963 – 1.13 0.307 706 6901 all phecode
536.7
Complications of gastrostomy, colostomy and
Complications of gastrostomy, colostomy and enterostomy
 Digestive 1.03 0.93 – 1.14 0.588 407 4059 all phecode
536.8
Dyspepsia and other specified disorders of
Dyspepsia and other specified disorders of function of stomach
 Digestive 0.989 0.945 – 1.03 0.631 2150 21094 all phecode
537 Other disorders of stomach and duodenum Digestive 0.99 0.954 – 1.03 0.578 3183 30048 all phecode
537.1 Lesions of stomach and duodenum Digestive 1.04 0.892 – 1.21 0.64 173 1725 all phecode
539 Bariatric surgery Digestive 0.94 0.891 – 0.991 0.022 1509 15074 all phecode
540 Appendiceal conditions Digestive 1 0.914 – 1.1 0.939 495 4948 all phecode
540.1 Appendicitis Digestive 0.99 0.897 – 1.09 0.843 425 4239 all phecode
540.11 Acute appendicitis Digestive 1.02 0.914 – 1.14 0.738 353 3511 all phecode
550 Abdominal hernia Digestive 0.993 0.967 – 1.02 0.603 6768 37731 all phecode
550.1 Inguinal hernia Digestive 0.973 0.926 – 1.02 0.289 1744 16488 all phecode
550.2 Diaphragmatic hernia Digestive 1.01 0.967 – 1.05 0.771 2817 25849 all phecode
550.3 Femoral hernia Digestive 0.969 0.811 – 1.16 0.729 131 1291 all phecode
550.4 Umbilical hernia Digestive 0.961 0.907 – 1.02 0.173 1313 13110 all phecode
550.5 Ventral hernia Digestive 0.979 0.937 – 1.02 0.349 2241 22163 all phecode
550.6 Incisional hernia Digestive 0.956 0.903 – 1.01 0.119 1313 13111 all phecode
555
Inflammatory bowel disease and other
Inflammatory bowel disease and other gastroenteritis and colitis
 Digestive 1.02 0.963 – 1.07 0.559 1536 15153 all phecode
555.1 Regional enteritis Digestive 1.01 0.944 – 1.08 0.748 919 9095 all phecode
555.2 Ulcerative colitis Digestive 1.01 0.944 – 1.08 0.758 937 9315 all phecode
555.21 Ulcerative colitis (chronic) Digestive 1.04 0.95 – 1.14 0.394 537 5315 all phecode
556 Ulceration of the lower GI tract Digestive 0.989 0.91 – 1.08 0.798 632 6267 all phecode
556.1 Ulceration of intestine Digestive 0.986 0.902 – 1.08 0.757 551 5451 all phecode
556.11
Angiodysplasia of intestine (without mention of
Angiodysplasia of intestine (without mention of hemorrhage)
 Digestive 0.972 0.843 – 1.12 0.696 214 2093 all phecode
557 Intestinal malabsorption (non-celiac) Digestive 0.972 0.924 – 1.02 0.275 1716 16490 all phecode
557.1 Celiac disease Digestive 0.949 0.858 – 1.05 0.305 421 4026 all phecode
558 Noninfectious gastroenteritis Digestive 1 0.969 – 1.04 0.806 3458 26408 all phecode
559 Ileostomy status Digestive 0.993 0.929 – 1.06 0.839 957 9565 all phecode
560 Intestinal obstruction without mention of hernia Digestive 0.993 0.956 – 1.03 0.734 3004 24851 all phecode
560.1 Paralytic ileus Digestive 1.02 0.969 – 1.07 0.453 1627 15714 all phecode
560.2 Impaction of intestine Digestive 0.903 0.811 – 1 0.0603 387 3779 all phecode
560.3 Peritoneal or intestinal adhesions Digestive 0.955 0.842 – 1.08 0.468 266 2647 all phecode
560.4 Other intestinal obstruction Digestive 0.98 0.931 – 1.03 0.44 1651 16170 all phecode
561 Symptoms involving digestive system Digestive 0.957 0.918 – 0.998 0.0381 2608 21766 all phecode
562 Diverticulosis and diverticulitis Digestive 0.992 0.964 – 1.02 0.593 6295 23431 all phecode
562.1 Diverticulosis Digestive 0.992 0.964 – 1.02 0.609 6246 23383 all phecode
562.2 Diverticulitis Digestive 0.966 0.917 – 1.02 0.191 1611 15162 all phecode
564 Functional digestive disorders Digestive 1 0.98 – 1.02 0.858 11411 28676 all phecode
564.1 Irritable Bowel Syndrome Digestive 1 0.965 – 1.04 0.961 3457 22266 all phecode
564.9 Personal history of diseases of digestive system Digestive 0.988 0.951 – 1.03 0.531 3074 25861 all phecode
565 Anal and rectal conditions Digestive 1.02 0.986 – 1.06 0.223 3355 30757 all phecode
565.1 Anal and rectal polyp Digestive 1.02 0.961 – 1.08 0.55 1305 12649 all phecode
567 Peritonitis and retroperitoneal infections Digestive 0.997 0.943 – 1.05 0.929 1364 13616 all phecode
568 Other disorders of peritoneum Digestive 0.972 0.924 – 1.02 0.256 1705 17038 all phecode
568.1
Peritoneal adhesions (postoperative)
Peritoneal adhesions (postoperative) (postinfection)
 Digestive 0.947 0.893 – 1 0.0695 1247 12468 all phecode
569 Other disorders of intestine Digestive 1.01 0.985 – 1.03 0.452 8079 35231 all phecode
569.1 Toxic gastroenteritis and colitis Digestive 1.1 0.978 – 1.23 0.112 326 3260 all phecode
569.2 Gastrointestinal complications Digestive 0.962 0.911 – 1.02 0.173 1395 13933 all phecode
571 Chronic liver disease and cirrhosis Digestive 1.02 0.986 – 1.05 0.293 4610 32562 all phecode
571.5 Other chronic nonalcoholic liver disease Digestive 1.01 0.98 – 1.04 0.472 4342 32234 all phecode
571.51 Cirrhosis of liver without mention of alcohol Digestive 0.991 0.929 – 1.06 0.782 1018 10095 all phecode
571.6 Primary biliary cirrhosis Digestive 0.986 0.846 – 1.15 0.858 179 1790 all phecode
571.8
Liver abscess and sequelae of chronic liver
Liver abscess and sequelae of chronic liver disease
 Digestive 1.03 0.962 – 1.1 0.414 950 9498 all phecode
571.81 Portal hypertension Digestive 0.986 0.905 – 1.07 0.749 573 5730 all phecode
572 Ascites (non malignant) Digestive 0.97 0.929 – 1.01 0.168 2278 22675 all phecode
573 Other disorders of liver Digestive 1.02 0.989 – 1.05 0.23 5599 33620 all phecode
573.1 Chronic passive congestion of liver Digestive 0.881 0.731 – 1.06 0.183 136 1359 all phecode
573.2 Liver replaced by transplant Digestive 0.995 0.881 – 1.12 0.939 292 2920 all phecode
573.3 Hepatomegaly Digestive 0.976 0.887 – 1.07 0.613 470 4700 all phecode
573.4 Acute and subacute necrosis of liver Digestive 1.06 0.949 – 1.19 0.289 316 3149 all phecode
573.5 Jaundice (not of newborn) Digestive 1.01 0.943 – 1.08 0.816 958 9496 all phecode
573.6
Nonspecific elevation of levels of transaminase
Nonspecific elevation of levels of transaminase or lactic acid dehydrogenase [LDH]
 Digestive 1.01 0.975 – 1.06 0.467 2756 26470 all phecode
573.7 Abnormal results of function study of liver Digestive 1.01 0.969 – 1.05 0.721 3018 27774 all phecode
573.9 Abnormal serum enzyme levels Digestive 1.03 0.997 – 1.06 0.0733 4679 33866 all phecode
574 Cholelithiasis and cholecystitis Digestive 0.984 0.949 – 1.02 0.387 3177 30809 all phecode
574.1 Cholelithiasis Digestive 0.978 0.941 – 1.02 0.254 2924 28874 all phecode
574.11 Cholelithiasis with acute cholecystitis Digestive 0.929 0.831 – 1.04 0.195 342 3412 all phecode
574.12 Cholelithiasis with other cholecystitis Digestive 1 0.917 – 1.09 0.991 553 5501 all phecode
574.2 Calculus of bile duct Digestive 0.964 0.898 – 1.04 0.313 852 8503 all phecode
574.3 Cholecystitis without cholelithiasis Digestive 0.974 0.906 – 1.05 0.466 822 8181 all phecode
575 Other biliary tract disease Digestive 0.968 0.927 – 1.01 0.141 2266 22555 all phecode
575.1 Cholangitis Digestive 1.01 0.907 – 1.13 0.836 354 3530 all phecode
575.2 Obstruction of bile duct Digestive 0.977 0.898 – 1.06 0.584 621 6201 all phecode
575.6 Cholesterolosis of gallbladder Digestive 1.02 0.885 – 1.18 0.773 207 2063 all phecode
575.7 Other disorders of gallbladder Digestive 0.935 0.874 – 1 0.0507 939 9382 all phecode
575.8 Other disorders of biliary tract Digestive 0.959 0.902 – 1.02 0.177 1154 11523 all phecode
575.9
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of biliary tract
 Digestive 0.926 0.815 – 1.05 0.24 260 2600 all phecode
577 Diseases of pancreas Digestive 0.97 0.929 – 1.01 0.182 2225 22106 all phecode
577.1 Acute pancreatitis Digestive 0.95 0.895 – 1.01 0.0909 1212 12110 all phecode
577.2 Chronic pancreatitis Digestive 0.909 0.829 – 0.997 0.0431 495 4950 all phecode
577.3 Cyst and pseudocyst of pancreas Digestive 0.95 0.87 – 1.04 0.247 570 5601 all phecode
578 Gastrointestinal hemorrhage Digestive 1.01 0.975 – 1.04 0.729 4554 37045 all phecode
578.1 Hematemesis Digestive 0.997 0.906 – 1.1 0.95 485 4842 all phecode
578.2 Blood in stool Digestive 0.987 0.948 – 1.03 0.504 2743 26554 all phecode
578.8 Hemorrhage of rectum and anus Digestive 1.02 0.976 – 1.07 0.382 2210 21750 all phecode
578.9 Hemorrhage of gastrointestinal tract Digestive 0.981 0.931 – 1.03 0.468 1562 15345 all phecode
579 Other symptoms involving abdomen and pelvis Digestive 0.983 0.952 – 1.01 0.275 4431 34209 all phecode
579.2 Splenomegaly Digestive 1 0.926 – 1.08 0.99 730 7262 all phecode
579.8 Nonspecific abnormal findings in stool contents Digestive 0.993 0.94 – 1.05 0.804 1410 13877 all phecode
580 Nephritis; nephrosis; renal sclerosis Genitourinary 0.995 0.947 – 1.04 0.834 1881 15516 all phecode
580.1 Glomerulonephritis Genitourinary 0.982 0.883 – 1.09 0.733 401 3992 all phecode
580.11 Proliferative glomerulonephritis Genitourinary 0.96 0.809 – 1.14 0.638 146 1440 all phecode
580.12 Non-proliferative glomerulonephritis Genitourinary 0.959 0.783 – 1.17 0.685 114 1128 all phecode
580.13 Acute glomerulonephritis, NOS Genitourinary 1.02 0.784 – 1.34 0.857 61 600 all phecode
580.14 Chronic glomerulonephritis, NOS Genitourinary 0.984 0.866 – 1.12 0.807 277 2760 all phecode
580.2
Nephrotic syndrome without mention of
Nephrotic syndrome without mention of glomerulonephritis
 Genitourinary 1.02 0.89 – 1.18 0.737 221 2193 all phecode
580.3
Nephritis and nephropathy without mention of
Nephritis and nephropathy without mention of glomerulonephritis
 Genitourinary 1 0.951 – 1.06 0.868 1502 11930 all phecode
580.31
Nephritis and nephropathy in diseases
Nephritis and nephropathy in diseases classified elsewhere
 Genitourinary 0.988 0.923 – 1.06 0.73 992 7228 all phecode
580.32
Nephritis and nephropathy with pathological
Nephritis and nephropathy with pathological lesion
 Genitourinary 1.03 0.953 – 1.12 0.433 683 6612 all phecode
580.4 Renal sclerosis, NOS Genitourinary 0.975 0.872 – 1.09 0.659 340 3400 all phecode
585 Renal failure Genitourinary 0.992 0.966 – 1.02 0.527 7470 32340 all phecode
585.1 Acute renal failure Genitourinary 0.997 0.965 – 1.03 0.871 4265 27230 all phecode
585.2 Renal failure NOS Genitourinary 0.953 0.887 – 1.03 0.197 832 8162 all phecode
585.3 Chronic renal failure [CKD] Genitourinary 0.996 0.967 – 1.03 0.809 5580 29470 all phecode
585.31 Renal dialysis Genitourinary 0.909 0.843 – 0.981 0.0143 747 7423 all phecode
585.32 End stage renal disease Genitourinary 0.957 0.897 – 1.02 0.188 1007 9783 all phecode
585.33 Chronic Kidney Disease, Stage III Genitourinary 1.01 0.97 – 1.05 0.685 3209 21312 all phecode
585.34 Chronic Kidney Disease, Stage IV Genitourinary 0.977 0.915 – 1.04 0.498 977 9190 all phecode
585.4 Chronic kidney disease, Stage I or II Genitourinary 1 0.946 – 1.06 0.913 1227 11191 all phecode
586 Other disorders of the kidney and ureters Genitourinary 1.01 0.982 – 1.03 0.563 7628 34189 all phecode
586.1 Anatomical abnormatilies of kidney and ureters Genitourinary 0.97 0.87 – 1.08 0.589 349 3480 all phecode
586.11 Small kidney Genitourinary 1 0.867 – 1.15 1 210 2093 all phecode
586.12 Vesicoureteral reflux Genitourinary 0.896 0.754 – 1.06 0.211 136 1360 all phecode
586.2 Cyst of kidney, acquired Genitourinary 0.987 0.934 – 1.04 0.65 1381 12912 all phecode
586.3 Vascular disorders of kidney/hypertrophy Genitourinary 1.05 0.903 – 1.21 0.548 187 1862 all phecode
586.4 Stricture/obstruction of ureter Genitourinary 0.957 0.912 – 1 0.0715 1821 17115 all phecode
587 Kidney replaced by transpant Genitourinary 0.931 0.866 – 1 0.055 819 8134 all phecode
588 Disorders resulting from impaired renal function Genitourinary 0.971 0.909 – 1.04 0.393 976 9389 all phecode
588.1 Renal osteodystrophy Genitourinary 1.03 0.915 – 1.16 0.616 290 2900 all phecode
588.2 Secondary hyperparathyroidism (of renal origin) Genitourinary 0.982 0.909 – 1.06 0.631 755 7275 all phecode
589 Abnormal results of function study of kidney Genitourinary 0.987 0.924 – 1.05 0.685 1007 9834 all phecode
590 Pyelonephritis Genitourinary 0.987 0.935 – 1.04 0.633 1461 14350 all phecode
591 Urinary tract infection Genitourinary 0.996 0.973 – 1.02 0.741 9873 32513 all phecode
592 Cystitis and urethritis Genitourinary 1 0.966 – 1.04 0.849 3038 24207 all phecode
592.1 Cystitis Genitourinary 1.01 0.968 – 1.05 0.74 2880 23279 all phecode
592.11 Acute cystitis Genitourinary 1 0.954 – 1.05 0.941 1783 16452 all phecode
592.12 Chronic cystitis Genitourinary 0.984 0.864 – 1.12 0.814 239 2343 all phecode
592.13 Chronic interstitial cystitis Genitourinary 1.01 0.916 – 1.12 0.816 431 4310 all phecode
592.2 Urethritis and urethral syndrome Genitourinary 1.03 0.888 – 1.19 0.723 210 2093 all phecode
593 Hematuria Genitourinary 1.02 0.986 – 1.05 0.287 4859 32063 all phecode
593.1 Gross hematuria Genitourinary 0.98 0.93 – 1.03 0.439 1585 14824 all phecode
593.2 Microscopic hematuria Genitourinary 1.06 0.999 – 1.14 0.0537 1049 10301 all phecode
594 Urinary calculus Genitourinary 1 0.976 – 1.03 0.896 6707 38209 all phecode
594.1 Calculus of kidney Genitourinary 1.01 0.978 – 1.03 0.714 6273 38051 all phecode
594.2 Calculus of lower urinary tract Genitourinary 1.08 0.975 – 1.21 0.135 366 3638 all phecode
594.3 Calculus of ureter Genitourinary 1.01 0.953 – 1.06 0.801 1361 13561 all phecode
594.8 Renal colic Genitourinary 1.07 0.96 – 1.2 0.219 356 3560 all phecode
595 Hydronephrosis Genitourinary 0.962 0.915 – 1.01 0.136 1670 16658 all phecode
596 Other disorders of bladder Genitourinary 0.999 0.962 – 1.04 0.945 3074 28020 all phecode
596.1 Bladder neck obstruction Genitourinary 0.93 0.837 – 1.03 0.179 400 3942 all phecode
596.5 Functional disorders of bladder Genitourinary 0.983 0.936 – 1.03 0.507 1719 17049 all phecode
597 Other disorders of urethra and urinary tract Genitourinary 1.01 0.948 – 1.07 0.827 1211 11998 all phecode
597.1 Urethral stricture (not specified as infectious) Genitourinary 0.974 0.897 – 1.06 0.518 661 6537 all phecode
597.2 Urinary complications NEC Genitourinary 0.965 0.905 – 1.03 0.27 1049 10479 all phecode
597.8 Urethral hypermobility/ISD Genitourinary 0.94 0.81 – 1.09 0.41 189 1873 all phecode
598 Abnormal findings on examination of urine Genitourinary 1.02 0.86 – 1.21 0.828 138 1356 all phecode
598.4 Other cells and casts in urine Genitourinary 1.06 0.882 – 1.26 0.555 122 1192 all phecode
599 Other symptoms/disorders or the urinary system Genitourinary 1.01 0.986 – 1.03 0.534 14168 30681 all phecode
599.1 Urinary obstruction Genitourinary 0.876 0.811 – 0.946 0.000702 728 6861 all phecode
599.2 Retention of urine Genitourinary 1 0.972 – 1.03 0.859 5034 28305 all phecode
599.3 Dysuria Genitourinary 1.01 0.974 – 1.04 0.695 4397 27849 all phecode
599.4 Urinary incontinence Genitourinary 1.01 0.985 – 1.04 0.334 5599 26960 all phecode
599.5 Frequency of urination and polyuria Genitourinary 1.01 0.983 – 1.04 0.403 5498 28723 all phecode
599.6 Oliguria and anuria Genitourinary 0.963 0.886 – 1.05 0.384 599 5902 all phecode
599.7 Urethral discharge Genitourinary 1.05 0.87 – 1.26 0.63 118 1175 all phecode
599.8 Other symptoms involving urinary system Genitourinary 1.01 0.977 – 1.04 0.647 5446 27963 all phecode
599.9 Other abnormality of urination Genitourinary 0.996 0.959 – 1.04 0.854 3041 24877 all phecode
600 Hyperplasia of prostate Genitourinary 0.997 0.959 – 1.04 0.862 4063 11364 all phecode
601 Inflammatory diseases of prostate Genitourinary 0.952 0.893 – 1.01 0.131 1044 9665 all phecode
601.1 Prostatitis Genitourinary 0.964 0.877 – 1.06 0.452 477 4596 all phecode
601.11 Acute prostatitis Genitourinary 1.13 0.931 – 1.37 0.215 124 1200 all phecode
601.12 Chronic prostatitis Genitourinary 0.911 0.738 – 1.12 0.387 95 943 all phecode
601.3 Orchitis and epididymitis Genitourinary 0.977 0.879 – 1.09 0.672 389 3822 all phecode
601.4 Balanoposthitis Genitourinary 0.889 0.744 – 1.06 0.194 127 1224 all phecode
601.8
Other inflammatory disorders of male genital
Other inflammatory disorders of male genital organs
 Genitourinary 0.932 0.79 – 1.1 0.4 161 1591 all phecode
602 Other disorders of prostate Genitourinary 0.966 0.867 – 1.08 0.527 361 3399 all phecode
602.3 Dysplasia of prostate Genitourinary 0.889 0.703 – 1.12 0.327 77 730 all phecode
603 Other disorders of testis Genitourinary 0.924 0.838 – 1.02 0.115 440 4354 all phecode
603.1 Hydrocele Genitourinary 0.85 0.753 – 0.959 0.00849 293 2882 all phecode
603.2 Spermatocele Genitourinary 1.01 0.861 – 1.19 0.882 156 1539 all phecode
604 Disorders of penis Genitourinary 0.937 0.866 – 1.01 0.105 685 6748 all phecode
604.1 Redundant prepuce and phimosis/BXO Genitourinary 0.952 0.808 – 1.12 0.551 155 1540 all phecode
604.3 Peyronie's disease Genitourinary 0.961 0.833 – 1.11 0.589 215 2132 all phecode
605 Erectile dysfunction [ED] Genitourinary 0.996 0.96 – 1.03 0.849 3776 12700 all phecode
608 Other disorders of male genital organs Genitourinary 0.999 0.949 – 1.05 0.965 1645 13758 all phecode
609 Male infertility and abnormal spermatozoa Genitourinary 0.922 0.833 – 1.02 0.114 424 4196 all phecode
609.1 Infertility, male Genitourinary 0.903 0.8 – 1.02 0.0991 302 2992 all phecode
609.11 Azoospermia and oligospermia Genitourinary 0.787 0.636 – 0.974 0.0276 95 950 all phecode
609.2 Abnormal spermatozoa Genitourinary 0.993 0.847 – 1.16 0.932 154 1519 all phecode
610 Benign mammary dysplasias Genitourinary 1 0.967 – 1.04 0.875 3683 16548 all phecode
610.1 Cystic mastopathy Genitourinary 0.987 0.937 – 1.04 0.617 1633 14191 all phecode
610.2 Fibroadenosis of breast Genitourinary 0.857 0.662 – 1.11 0.24 60 600 all phecode
610.4 Benign neoplasm of breast Genitourinary 1.01 0.972 – 1.05 0.572 2837 16430 all phecode
610.8 Other specified benign mammary dysplasias Genitourinary 0.998 0.942 – 1.06 0.954 1269 12191 all phecode
611 Abnormal findings on mammogram or breast exam Genitourinary 1.02 0.989 – 1.05 0.223 6067 18690 all phecode
611.1 Abnormal mammogram Genitourinary 1.01 0.978 – 1.04 0.537 4980 16120 all phecode
611.11 Mammographic microcalcification Genitourinary 1.04 0.975 – 1.1 0.25 1122 10394 all phecode
611.3 Lump or mass in breast Genitourinary 1.01 0.977 – 1.05 0.463 3549 18572 all phecode
612
Breast conditions, congenital or relating to
Breast conditions, congenital or relating to hormones
 Genitourinary 1.01 0.949 – 1.08 0.728 1051 10425 all phecode
612.1 Galactorrhea Genitourinary 1.1 0.923 – 1.31 0.291 139 1390 all phecode
612.2 Hypertrophy of breast (Gynecomastia) Genitourinary 1.02 0.945 – 1.09 0.661 800 7962 all phecode
612.3 Congenital anomalies of breast Genitourinary 0.807 0.644 – 1.01 0.0621 83 810 all phecode
613 Other nonmalignant breast conditions Genitourinary 1.01 0.978 – 1.05 0.479 3897 22072 all phecode
613.1 Inflammatory disease of breast Genitourinary 0.974 0.894 – 1.06 0.553 593 5874 all phecode
613.5 Mastodynia Genitourinary 1 0.954 – 1.06 0.879 1675 16203 all phecode
613.7 Other signs and symptoms in breast Genitourinary 0.991 0.923 – 1.06 0.803 883 8754 all phecode
613.8 Other specified disorders of breast Genitourinary 1.04 0.97 – 1.11 0.278 932 9248 all phecode
613.9 Breast disorder NOS Genitourinary 0.998 0.945 – 1.05 0.955 1465 14174 all phecode
614 Inflammatory diseases of female pelvic organs Genitourinary 0.999 0.964 – 1.04 0.961 3715 19647 all phecode
614.1
Pelvic peritoneal adhesions, female
Pelvic peritoneal adhesions, female (postoperative) (postinfection)
 Genitourinary 1.01 0.904 – 1.13 0.836 337 3370 all phecode
614.3 Pelvic inflammatory disease (PID) Genitourinary 1.04 0.946 – 1.15 0.411 478 4773 all phecode
614.31 Acute inflammatory pelvic disease Genitourinary 1.03 0.823 – 1.28 0.811 94 933 all phecode
614.32 Chronic inflammatory pelvic disease Genitourinary 1.06 0.905 – 1.23 0.484 186 1842 all phecode
614.33 Pelvic inflammatory disease, NOS Genitourinary 1.08 0.945 – 1.24 0.254 246 2460 all phecode
614.4 Inflammatory diseases of uterus, except cervix Genitourinary 1.01 0.861 – 1.18 0.916 165 1639 all phecode
614.5
Inflammatory disease of cervix, vagina, and
Inflammatory disease of cervix, vagina, and vulva
 Genitourinary 0.995 0.958 – 1.03 0.797 3180 19539 all phecode
614.51 Cervicitis and endocervicitis Genitourinary 1.02 0.9 – 1.16 0.754 264 2640 all phecode
614.52 Vaginitis and vulvovaginitis Genitourinary 0.989 0.949 – 1.03 0.578 2732 18924 all phecode
614.53 Cyst or abscess of Bartholin's gland Genitourinary 1.05 0.876 – 1.26 0.599 132 1311 all phecode
614.54 Abscess or ulceration of vulva Genitourinary 0.926 0.808 – 1.06 0.268 225 2244 all phecode
615 Endometriosis Genitourinary 0.989 0.938 – 1.04 0.668 1585 14666 all phecode
618 Genital prolapse Genitourinary 1.01 0.967 – 1.06 0.586 2079 17915 all phecode
618.1 Prolapse of vaginal walls Genitourinary 1.01 0.957 – 1.07 0.686 1408 13456 all phecode
618.2 Uterine/Uterovaginal prolapse Genitourinary 0.979 0.897 – 1.07 0.641 542 5390 all phecode
618.5 Prolapse of vaginal vault after hysterectomy Genitourinary 1.1 0.982 – 1.24 0.0962 317 3162 all phecode
618.6 Vaginal enterocele, congenital or acquired Genitourinary 0.972 0.88 – 1.07 0.57 441 4394 all phecode
619 Noninflammatory female genital disorders Genitourinary 0.983 0.954 – 1.01 0.258 5728 18687 all phecode
619.1
Noninflammatory disorders of ovary, fallopian
Noninflammatory disorders of ovary, fallopian tube, and broad ligament
 Genitourinary 0.944 0.889 – 1 0.0565 1233 12082 all phecode
619.2 Disorders of uterus, NEC Genitourinary 1.03 0.949 – 1.13 0.448 591 5897 all phecode
619.3 Noninflammatory disorders of cervix Genitourinary 0.953 0.867 – 1.05 0.315 483 4823 all phecode
619.4 Noninflammatory disorders of vagina Genitourinary 0.975 0.935 – 1.02 0.25 2525 18404 all phecode
619.5 Noninflammatory disorders of vulva and perineum Genitourinary 1.02 0.957 – 1.08 0.612 1189 11717 all phecode
620 Dysplasia of female genital organs Genitourinary 0.913 0.824 – 1.01 0.0847 395 3950 all phecode
620.1 Dysplasia of cervix Genitourinary 0.899 0.771 – 1.05 0.172 178 1780 all phecode
621 Endometrial hyperplasia Genitourinary 0.897 0.812 – 0.99 0.0311 437 4370 all phecode
622 Polyp of female genital organs Genitourinary 0.968 0.917 – 1.02 0.249 1449 14264 all phecode
622.1 Polyp of corpus uteri Genitourinary 0.967 0.909 – 1.03 0.28 1132 11189 all phecode
622.2 Mucous polyp of cervix Genitourinary 0.948 0.858 – 1.05 0.291 445 4444 all phecode
623 Hypertrophy of female genital organs Genitourinary 0.973 0.906 – 1.05 0.461 824 8165 all phecode
624 Symptoms involving female genital tract Genitourinary 0.973 0.919 – 1.03 0.34 1348 12518 all phecode
624.1 Dystrophy of female genital tract Genitourinary 1.01 0.873 – 1.16 0.936 216 2155 all phecode
624.2 Atrophy of female genital tract Genitourinary 0.845 0.655 – 1.09 0.192 64 615 all phecode
624.9 stress incontinence, female Genitourinary 0.99 0.944 – 1.04 0.677 1935 15408 all phecode
625
Pain and other symptoms associated with female
Pain and other symptoms associated with female genital organs
 Genitourinary 0.985 0.955 – 1.02 0.324 5653 17303 all phecode
625.1 Dyspareunia Genitourinary 0.998 0.941 – 1.06 0.948 1267 12474 all phecode
626
Disorders of menstruation and other abnormal
Disorders of menstruation and other abnormal bleeding from female genital tract
 Genitourinary 0.973 0.944 – 1 0.0889 5940 15585 all phecode
626.1 Irregular menstrual cycle/bleeding Genitourinary 0.97 0.936 – 1 0.0879 4315 14604 all phecode
626.11 Absent or infrequent menstruation Genitourinary 0.995 0.933 – 1.06 0.884 1062 8531 all phecode
626.12 Excessive or frequent menstruation Genitourinary 0.953 0.91 – 0.999 0.047 2097 11991 all phecode
626.13 Irregular menstrual cycle Genitourinary 0.972 0.926 – 1.02 0.255 1957 12265 all phecode
626.14 Irregular menstrual bleeding Genitourinary 0.95 0.889 – 1.02 0.13 970 8996 all phecode
626.15 Infertility, female, associated with anovulation Genitourinary 0.954 0.859 – 1.06 0.387 394 3789 all phecode
626.2 Dysmenorrhea Genitourinary 0.976 0.922 – 1.03 0.411 1373 9857 all phecode
626.4 Premenstrual tension syndromes Genitourinary 0.968 0.864 – 1.08 0.569 336 3308 all phecode
626.8 Infertility, female Genitourinary 1.01 0.936 – 1.09 0.836 817 6741 all phecode
627 Menopausal and postmenopausal disorders Genitourinary 0.973 0.941 – 1.01 0.12 4560 14557 all phecode
627.1 Postmenopausal bleeding Genitourinary 0.967 0.909 – 1.03 0.295 1146 10338 all phecode
627.2 Symptomatic menopause Genitourinary 0.978 0.939 – 1.02 0.274 3017 13763 all phecode
627.21 Symptomatic artificial menopause Genitourinary 1.11 0.935 – 1.31 0.237 152 1514 all phecode
627.22
Need for Hormone replacement therapy
Need for Hormone replacement therapy (postmenopausal)
 Genitourinary 0.968 0.868 – 1.08 0.565 356 3513 all phecode
627.3 Postmenopausal atrophic vaginitis Genitourinary 0.96 0.898 – 1.03 0.225 997 9484 all phecode
627.4 Premenopausal menorrhagia Genitourinary 0.94 0.842 – 1.05 0.263 361 3580 all phecode
627.5 Premature menopause and other ovarian failure Genitourinary 0.872 0.774 – 0.982 0.0244 309 3082 all phecode
628 Ovarian cyst Genitourinary 0.975 0.93 – 1.02 0.313 1945 13838 all phecode
634 Miscarriage; stillbirth Pregnancy Complications 1.02 0.945 – 1.09 0.673 826 8047 all phecode
634.1 Missed abortion/Hydatidiform mole Pregnancy Complications 0.988 0.871 – 1.12 0.848 273 2715 all phecode
634.3 Ectopic pregnancy Pregnancy Complications 1.04 0.866 – 1.25 0.661 117 1170 all phecode
635
Hemorrhage during pregnancy; childbirth and
Hemorrhage during pregnancy; childbirth and postpartum
 Pregnancy Complications 1.03 0.942 – 1.12 0.543 563 5309 all phecode
635.2
Antepartum hemorrhage, abruptio placentae, and
Antepartum hemorrhage, abruptio placentae, and placenta previa
 Pregnancy Complications 1.02 0.914 – 1.13 0.759 370 3629 all phecode
635.3 Placenta previa and abruptio placenta Pregnancy Complications 0.987 0.875 – 1.11 0.836 288 2850 all phecode
636
Early or threatened labor; hemorrhage in early
Early or threatened labor; hemorrhage in early pregnancy
 Pregnancy Complications 1.02 0.956 – 1.09 0.553 1080 7870 all phecode
636.1 Threatened premature labor Pregnancy Complications 0.94 0.847 – 1.04 0.249 380 3799 all phecode
636.2 Early onset of delivery Pregnancy Complications 0.918 0.815 – 1.03 0.159 288 2868 all phecode
636.3 Hemorrhage in early pregnancy Pregnancy Complications 1.07 0.974 – 1.19 0.152 441 4365 all phecode
636.8 Cervical incompetence Pregnancy Complications 0.843 0.67 – 1.06 0.146 77 770 all phecode
637
Short gestation; low birth weight; and fetal
Short gestation; low birth weight; and fetal growth retardation
 Pregnancy Complications 1.02 0.815 – 1.27 0.884 85 850 all phecode
642
Hypertension complicating pregnancy
Hypertension complicating pregnancy, childbirth, and the puerperium
 Pregnancy Complications 1.03 0.946 – 1.12 0.496 585 5725 all phecode
642.1 Preeclampsia and eclampsia Pregnancy Complications 1.03 0.912 – 1.16 0.661 302 3013 all phecode
643 Excessive vomiting in pregnancy Pregnancy Complications 1.02 0.897 – 1.16 0.753 252 2506 all phecode
643.1 Hyperemesis gravidarum Pregnancy Complications 0.992 0.822 – 1.2 0.937 119 1190 all phecode
644 Anemia during pregnancy Pregnancy Complications 0.967 0.843 – 1.11 0.626 224 2224 all phecode
646 Other complications of pregnancy NEC Pregnancy Complications 1.01 0.941 – 1.09 0.768 855 6531 all phecode
647
Infectious and parasitic complications
Infectious and parasitic complications affecting pregnancy
 Pregnancy Complications 0.981 0.851 – 1.13 0.786 211 2093 all phecode
647.1
Infections of genitourinary tract during
Infections of genitourinary tract during pregnancy
 Pregnancy Complications 0.916 0.797 – 1.05 0.218 222 2213 all phecode
647.3 Major puerperal infection Pregnancy Complications 1.01 0.79 – 1.29 0.936 65 650 all phecode
649
Other conditions or status of the mother
Other conditions or status of the mother complicating pregnancy, childbirth, or the puerperium
 Pregnancy Complications 1.04 0.978 – 1.1 0.214 1275 8010 all phecode
649.1
Diabetes or abnormal glucose tolerance
Diabetes or abnormal glucose tolerance complicating pregnancy
 Pregnancy Complications 1.08 0.994 – 1.17 0.0693 649 5687 all phecode
653
Problems associated with amniotic cavity and
Problems associated with amniotic cavity and membranes
 Pregnancy Complications 1.05 0.967 – 1.15 0.231 587 5463 all phecode
654.1
Abnormality of organs and soft tissues of
Abnormality of organs and soft tissues of pelvis complicating pregnancy, childbirth, or the puerperium
 Pregnancy Complications 1.13 0.984 – 1.31 0.0813 207 2055 all phecode
654.2 Rhesus isoimmunization in pregnancy Pregnancy Complications 1.13 0.979 – 1.31 0.095 204 2040 all phecode
655
Known or suspected fetal abnormality affecting
Known or suspected fetal abnormality affecting management of mother
 Pregnancy Complications 1.07 1.01 – 1.13 0.0168 1624 10064 all phecode
655.1 Abnormality in fetal heart rate or rhythm Pregnancy Complications 1.07 0.983 – 1.16 0.118 616 5533 all phecode
656 Other perinatal conditions of fetus or newborn Pregnancy Complications 1.01 0.941 – 1.08 0.804 898 7014 all phecode
656.2 Respiratory conditions of fetus and newborn Pregnancy Complications 0.83 0.639 – 1.08 0.162 66 660 all phecode
669 Complications of labor and delivery NEC Pregnancy Complications 1.03 0.964 – 1.11 0.341 887 6802 all phecode
671
Venous/cerebrovascular complications embolism
Venous/cerebrovascular complications embolism in pregnancy and the puerperium
 Pregnancy Complications 1 0.879 – 1.15 0.945 236 2351 all phecode
674 Other complications of the puerperium NEC Pregnancy Complications 1 0.845 – 1.18 1 158 1580 all phecode
676
Other disorders of the breast associated with
Other disorders of the breast associated with childbirth and disorders of lactation
 Pregnancy Complications 0.994 0.852 – 1.16 0.941 184 1814 all phecode
681 Superficial cellulitis and abscess Dermatologic 1 0.978 – 1.03 0.749 6500 38394 all phecode
681.1 Cellulitis and abscess of fingers/toes Dermatologic 1.01 0.956 – 1.08 0.643 1256 11462 all phecode
681.2 Cellulitis and abscess of face/neck Dermatologic 0.993 0.93 – 1.06 0.831 1007 9981 all phecode
681.3 Cellulitis and abscess of arm/hand Dermatologic 0.973 0.93 – 1.02 0.239 2123 19952 all phecode
681.5 Cellulitis and abscess of leg, except foot Dermatologic 0.979 0.937 – 1.02 0.353 2252 20944 all phecode
681.6 Cellulitis and abscess of foot, toe Dermatologic 0.992 0.945 – 1.04 0.764 1820 16893 all phecode
681.7 Cellulitis and abscess of trunk Dermatologic 1 0.952 – 1.06 0.892 1572 15588 all phecode
686
Other local infections of skin and subcutaneous
Other local infections of skin and subcutaneous tissue
 Dermatologic 1 0.958 – 1.05 0.954 2257 21750 all phecode
686.1 Carbuncle and furuncle Dermatologic 1.02 0.936 – 1.12 0.63 558 5504 all phecode
686.2 Impetigo Dermatologic 0.979 0.883 – 1.08 0.682 414 4117 all phecode
686.3 Pilonidal cyst Dermatologic 0.982 0.833 – 1.16 0.83 160 1594 all phecode
686.4 Pyogenic granuloma Dermatologic 0.852 0.722 – 1 0.057 158 1570 all phecode
686.5 Pyoderma Dermatologic 0.999 0.774 – 1.29 0.991 63 630 all phecode
687 Symptoms affecting skin Dermatologic 0.987 0.938 – 1.04 0.597 1690 16343 all phecode
687.1 Rash and other nonspecific skin eruption Dermatologic 0.998 0.972 – 1.02 0.858 7007 34623 all phecode
687.3 Changes in skin texture Dermatologic 0.972 0.879 – 1.08 0.583 415 4121 all phecode
687.4 Disturbance of skin sensation Dermatologic 1.01 0.981 – 1.04 0.591 6375 34216 all phecode
689 Disorder of skin and subcutaneous tissue NOS Dermatologic 1.02 0.992 – 1.04 0.207 9311 37335 all phecode
690 Erythematosquamous dermatosis Dermatologic 1.02 0.992 – 1.05 0.145 5184 31581 all phecode
690.1 Seborrheic dermatitis Dermatologic 1.02 0.992 – 1.05 0.152 5174 31553 all phecode
691 Congenital anomalies of skin Dermatologic 0.901 0.825 – 0.984 0.0206 541 5337 all phecode
691.3 Congenital pigmentary anomalies of skin Dermatologic 0.955 0.738 – 1.23 0.724 62 613 all phecode
694 Dyschromia and Vitiligo Dermatologic 0.992 0.945 – 1.04 0.741 1861 17936 all phecode
694.1 Vitiligo Dermatologic 0.961 0.808 – 1.14 0.65 137 1347 all phecode
694.2 Other dyschromia Dermatologic 0.985 0.937 – 1.04 0.567 1674 16183 all phecode
694.3 Vascular disorders of skin Dermatologic 1.16 0.925 – 1.46 0.196 82 819 all phecode
695 Erythematous conditions Dermatologic 0.952 0.921 – 0.984 0.00361 4120 30247 all phecode
695.1 Toxic erythema Dermatologic 0.831 0.652 – 1.06 0.135 70 688 all phecode
695.2 Bullous dermatoses Dermatologic 0.95 0.755 – 1.19 0.659 85 805 all phecode
695.3 Rosacea Dermatologic 0.959 0.913 – 1.01 0.0905 1816 17663 all phecode
695.4 Lupus (localized and systemic) Dermatologic 0.931 0.859 – 1.01 0.0831 672 6686 all phecode
695.41 Cutaneous lupus erythematosus Dermatologic 0.975 0.853 – 1.11 0.708 247 2437 all phecode
695.42 Systemic lupus erythematosus Dermatologic 0.93 0.856 – 1.01 0.0861 637 6337 all phecode
695.7 Prurigo and Lichen Dermatologic 0.916 0.842 – 0.997 0.0414 605 5986 all phecode
695.8 Other specified erythematous conditions Dermatologic 0.887 0.825 – 0.954 0.0012 812 7980 all phecode
695.81 Erythema nodosum Dermatologic 0.946 0.726 – 1.23 0.683 55 550 all phecode
695.9 Unspecified erythematous condition Dermatologic 1.01 0.935 – 1.1 0.76 679 6756 all phecode
696 Psoriasis and related disorders Dermatologic 1.02 0.964 – 1.08 0.51 1401 13832 all phecode
696.3 Pityriasis Dermatologic 1.09 0.891 – 1.34 0.392 92 904 all phecode
696.4 Psoriasis Dermatologic 1.02 0.959 – 1.08 0.594 1311 12976 all phecode
696.41 Psoriasis vulgaris Dermatologic 1 0.943 – 1.06 0.962 1200 11867 all phecode
696.42 Psoriatic arthropathy Dermatologic 1.05 0.927 – 1.18 0.46 282 2810 all phecode
697 Sarcoidosis Dermatologic 0.961 0.858 – 1.08 0.494 333 3330 all phecode
698 Pruritus and related conditions Dermatologic 0.991 0.949 – 1.04 0.688 2254 21889 all phecode
700 Corns and callosities Dermatologic 0.965 0.911 – 1.02 0.234 1373 10894 all phecode
701
Other hypertrophic and atrophic conditions of
Other hypertrophic and atrophic conditions of skin
 Dermatologic 0.999 0.974 – 1.02 0.947 7651 38050 all phecode
701.1 Keratoderma, acquired Dermatologic 1.04 0.954 – 1.14 0.368 567 5524 all phecode
701.2 Scar conditions and fibrosis of skin Dermatologic 0.954 0.912 – 0.997 0.0362 2184 21550 all phecode
701.3 Circumscribed scleroderma Dermatologic 0.993 0.911 – 1.08 0.871 571 5660 all phecode
701.4 Keloid scar Dermatologic 0.945 0.866 – 1.03 0.207 578 5716 all phecode
701.5 Abnormal granulation tissue Dermatologic 0.952 0.859 – 1.06 0.348 400 3982 all phecode
702
Degenerative skin conditions and other
Degenerative skin conditions and other dermatoses
 Dermatologic 1.03 0.999 – 1.05 0.0601 6956 29525 all phecode
702.1 Actinic keratosis Dermatologic 1.01 0.979 – 1.05 0.486 4171 26529 all phecode
702.2 Seborrheic keratosis Dermatologic 1.03 0.999 – 1.06 0.0626 5480 31552 all phecode
702.4 Degenerative skin disorders Dermatologic 1.08 0.873 – 1.34 0.468 86 832 all phecode
703 Diseases of nail, NOS Dermatologic 1 0.95 – 1.05 0.99 1650 14562 all phecode
703.1 Ingrowing nail Dermatologic 0.961 0.897 – 1.03 0.262 920 8597 all phecode
704 Diseases of hair and hair follicles Dermatologic 1.01 0.969 – 1.04 0.754 3118 29542 all phecode
704.1 Alopecia Dermatologic 1.03 0.976 – 1.09 0.274 1408 13871 all phecode
704.11 Alopecia Areata Dermatologic 1.12 0.894 – 1.41 0.322 82 811 all phecode
704.12 Telogen effluvium Dermatologic 1.01 0.78 – 1.3 0.95 63 615 all phecode
704.2 Hirsutism Dermatologic 1.04 0.923 – 1.17 0.521 299 2946 all phecode
704.8
Other specified diseases of hair and hair
Other specified diseases of hair and hair follicles
 Dermatologic 1 0.954 – 1.05 0.931 1752 17189 all phecode
705 Disorders of sweat glands Dermatologic 0.927 0.851 – 1.01 0.0851 603 6012 all phecode
705.1 Dyshidrosis Dermatologic 0.861 0.73 – 1.02 0.0753 154 1540 all phecode
705.3 Hidradenitis Dermatologic 0.978 0.855 – 1.12 0.749 245 2440 all phecode
705.8 Hyperhidrosis Dermatologic 1.03 0.971 – 1.1 0.295 1112 10986 all phecode
706 Diseases of sebaceous glands Dermatologic 1.02 0.992 – 1.05 0.158 5995 39748 all phecode
706.1 Acne Dermatologic 1.02 0.981 – 1.06 0.305 2594 22570 all phecode
706.2 Sebaceous cyst Dermatologic 1.01 0.973 – 1.05 0.557 2814 26819 all phecode
706.3 Seborrhea Dermatologic 1.18 0.908 – 1.54 0.215 59 582 all phecode
706.8 Other specified diseases of sebaceous glands Dermatologic 1.02 0.966 – 1.07 0.527 1684 15289 all phecode
707 Chronic ulcer of skin Dermatologic 0.973 0.936 – 1.01 0.173 2871 26816 all phecode
707.1 Decubitus ulcer Dermatologic 1.02 0.952 – 1.1 0.525 825 8119 all phecode
707.2 Chronic ulcer of leg or foot Dermatologic 0.998 0.938 – 1.06 0.947 1108 9992 all phecode
707.3 Chronic ulcer of unspecified site Dermatologic 0.962 0.914 – 1.01 0.136 1641 16172 all phecode
709 Diffuse diseases of connective tissue Dermatologic 0.953 0.903 – 1.01 0.0801 1477 14427 all phecode
709.2 Sicca syndrome Dermatologic 0.985 0.899 – 1.08 0.751 505 4986 all phecode
709.3 Systemic sclerosis Dermatologic 0.879 0.763 – 1.01 0.0742 224 2209 all phecode
709.5 Dermatomyositis Dermatologic 0.92 0.738 – 1.15 0.455 92 892 all phecode
709.6
Other specified diffuse diseases of connective
Other specified diffuse diseases of connective tissue
 Dermatologic 0.887 0.715 – 1.1 0.276 90 892 all phecode
709.7 Unspecified diffuse connective tissue disease Dermatologic 0.92 0.86 – 0.985 0.016 917 9089 all phecode
710
Osteomyelitis, periostitis, and other
Osteomyelitis, periostitis, and other infections involving bone
 Musculoskeletal 0.972 0.917 – 1.03 0.341 1254 12103 all phecode
710.1 Osteomyelitis Musculoskeletal 0.978 0.922 – 1.04 0.474 1203 11636 all phecode
710.11 Acute osteomyelitis Musculoskeletal 0.989 0.908 – 1.08 0.798 590 5708 all phecode
710.12 Chronic osteomyelitis Musculoskeletal 0.925 0.847 – 1.01 0.088 531 5163 all phecode
710.19 Unspecified osteomyelitis Musculoskeletal 0.976 0.918 – 1.04 0.435 1153 11149 all phecode
711 Arthropathy associated with infections Musculoskeletal 0.872 0.789 – 0.965 0.00799 410 4099 all phecode
711.1 Pyogenic arthritis Musculoskeletal 0.927 0.822 – 1.05 0.218 290 2900 all phecode
712 Infective connective tissue disorders Musculoskeletal 0.901 0.773 – 1.05 0.181 178 1776 all phecode
713
Arthropathy associated with other disorders
Arthropathy associated with other disorders classified elsewhere
 Musculoskeletal 0.981 0.872 – 1.1 0.748 314 3028 all phecode
713.5
Arthropathy associated with neurological
Arthropathy associated with neurological disorders
 Musculoskeletal 1.02 0.882 – 1.19 0.765 194 1824 all phecode
714
Rheumatoid arthritis and other inflammatory
Rheumatoid arthritis and other inflammatory polyarthropathies
 Musculoskeletal 1 0.955 – 1.05 0.987 2086 18159 all phecode
714.1 Rheumatoid arthritis Musculoskeletal 0.983 0.934 – 1.03 0.509 1670 15087 all phecode
714.2 Juvenile rheumatoid arthritis Musculoskeletal 1.19 0.95 – 1.5 0.128 77 767 all phecode
715 Other inflammatory spondylopathies Musculoskeletal 0.982 0.925 – 1.04 0.543 1209 11967 all phecode
715.1 Sacroiliitis NEC Musculoskeletal 1.03 0.907 – 1.17 0.632 262 2611 all phecode
715.2 Ankylosing spondylitis Musculoskeletal 1.01 0.876 – 1.16 0.924 219 2182 all phecode
716 Other arthropathies Musculoskeletal 0.987 0.967 – 1.01 0.239 13482 31305 all phecode
716.1 Unspecified polyarthropathy or polyarthritis Musculoskeletal 0.991 0.854 – 1.15 0.905 192 1920 all phecode
716.2 Unspecified monoarthritis Musculoskeletal 1.04 0.875 – 1.24 0.642 131 1293 all phecode
716.9 Arthropathy NOS Musculoskeletal 0.987 0.966 – 1.01 0.23 13410 31294 all phecode
717 Polymyalgia Rheumatica Musculoskeletal 1.08 0.949 – 1.23 0.24 261 2565 all phecode
720 Spinal stenosis Musculoskeletal 1.01 0.978 – 1.05 0.521 3958 28539 all phecode
720.1 Spinal stenosis of lumbar region Musculoskeletal 1.01 0.968 – 1.05 0.735 2872 23656 all phecode
721 Spondylosis and allied disorders Musculoskeletal 0.991 0.963 – 1.02 0.553 5509 32391 all phecode
721.1 Spondylosis without myelopathy Musculoskeletal 0.992 0.963 – 1.02 0.597 5153 31896 all phecode
721.2 Spondylosis with myelopathy Musculoskeletal 0.995 0.927 – 1.07 0.898 867 8629 all phecode
721.8 Other allied disorders of spine Musculoskeletal 0.879 0.773 – 1 0.0503 262 2600 all phecode
722 Intervertebral disc disorders Musculoskeletal 1 0.978 – 1.03 0.729 6284 34317 all phecode
722.1 Displacement of intervertebral disc Musculoskeletal 1 0.97 – 1.04 0.828 3591 31411 all phecode
722.3 Schmorl's nodes Musculoskeletal 0.972 0.812 – 1.16 0.761 126 1248 all phecode
722.6 Degeneration of intervertebral disc Musculoskeletal 1 0.97 – 1.04 0.845 3957 30744 all phecode
722.7 Intervertebral disc disorder with myelopathy Musculoskeletal 1.01 0.918 – 1.1 0.888 515 5140 all phecode
722.8 Postlaminectomy syndrome Musculoskeletal 1.14 1.02 – 1.26 0.0157 397 3968 all phecode
722.9 Other and unspecified disc disorder Musculoskeletal 1.02 0.972 – 1.07 0.424 1932 19288 all phecode
723 Other disorders of cervical region Musculoskeletal 1.01 0.948 – 1.08 0.691 952 9495 all phecode
723.1 Torticollis Musculoskeletal 1.11 0.97 – 1.26 0.134 254 2522 all phecode
724 Other and unspecified disorders of back Musculoskeletal 1.01 0.982 – 1.05 0.382 4130 31954 all phecode
724.1 Disorders of sacrum Musculoskeletal 1.04 0.992 – 1.08 0.11 2307 21902 all phecode
724.2 Disorders of coccyx Musculoskeletal 1.03 0.936 – 1.14 0.505 426 4215 all phecode
724.8 Other symptoms referable to back Musculoskeletal 0.973 0.909 – 1.04 0.42 931 9295 all phecode
724.9 Other unspecified back disorders Musculoskeletal 1 0.95 – 1.06 0.899 1412 14087 all phecode
726 Peripheral enthesopathies and allied syndromes Musculoskeletal 0.988 0.966 – 1.01 0.321 9917 30176 all phecode
726.1 Enthesopathy Musculoskeletal 1 0.975 – 1.03 0.978 7507 30106 all phecode
726.2 Synoviopathy Musculoskeletal 0.944 0.885 – 1.01 0.0856 1015 9987 all phecode
726.3 Bursitis Musculoskeletal 0.981 0.934 – 1.03 0.448 1829 16722 all phecode
726.4 Calcaneal spur; Exostosis NOS Musculoskeletal 0.956 0.9 – 1.02 0.145 1193 11485 all phecode
727 Other disorders of synovium, tendon, and bursa Musculoskeletal 0.973 0.949 – 0.999 0.0426 7425 30105 all phecode
727.1 Synovitis and tenosynovitis Musculoskeletal 0.978 0.942 – 1.02 0.257 3092 24998 all phecode
727.2 Bursitis disorders Musculoskeletal 0.929 0.839 – 1.03 0.16 419 4112 all phecode
727.4 Ganglion and cyst of synovium, tendon, and bursa Musculoskeletal 0.994 0.94 – 1.05 0.842 1400 13621 all phecode
727.5 Rupture of synovium Musculoskeletal 1.02 0.928 – 1.12 0.667 480 4672 all phecode
727.6 Rupture of tendon, nontraumatic Musculoskeletal 0.976 0.936 – 1.02 0.259 2461 21948 all phecode
727.7 Contracture of tendon (sheath) Musculoskeletal 0.995 0.915 – 1.08 0.913 591 5893 all phecode
727.8 Plica syndrome Musculoskeletal 0.93 0.773 – 1.12 0.445 130 1264 all phecode
728 Disorders of muscle, ligament, and fascia Musculoskeletal 0.996 0.965 – 1.03 0.806 4546 29473 all phecode
728.1 Muscular calcification and ossification Musculoskeletal 1.16 0.927 – 1.45 0.194 85 843 all phecode
728.2 Laxity of ligament or hypermobility syndrome Musculoskeletal 0.998 0.886 – 1.12 0.972 297 2949 all phecode
728.7 Fasciitis Musculoskeletal 0.976 0.938 – 1.02 0.225 2814 23463 all phecode
728.71
Contracture of palmar fascia [Dupuytren's
Contracture of palmar fascia [Dupuytren's disease]
 Musculoskeletal 0.953 0.861 – 1.05 0.35 419 4138 all phecode
729 Other disorders of soft tissues Musculoskeletal 0.991 0.957 – 1.03 0.629 3642 27471 all phecode
729.1 Rheumatism, unspecified and fibrositis Musculoskeletal 0.95 0.751 – 1.2 0.667 74 726 all phecode
729.3 Panniculitis Musculoskeletal 0.947 0.78 – 1.15 0.577 119 1174 all phecode
729.7 Nontraumatic compartment syndrome Musculoskeletal 0.832 0.648 – 1.07 0.152 67 664 all phecode
731
Osteitis deformans and osteopathies associated
Osteitis deformans and osteopathies associated with other disorders classified elsewhere
 Musculoskeletal 0.863 0.744 – 1 0.0503 210 2091 all phecode
732 Osteochondropathies Musculoskeletal 0.971 0.873 – 1.08 0.59 361 3604 all phecode
732.1 Juvenile osteochondrosis Musculoskeletal 0.965 0.836 – 1.11 0.627 198 1969 all phecode
732.7 Osteochondritis dissecans Musculoskeletal 1.04 0.834 – 1.29 0.747 90 882 all phecode
733 Other disorders of bone and cartilage Musculoskeletal 1.01 0.981 – 1.05 0.426 4543 26941 all phecode
733.2 Cyst of bone Musculoskeletal 1.05 0.9 – 1.22 0.538 190 1900 all phecode
733.4 Aseptic necrosis of bone Musculoskeletal 0.995 0.909 – 1.09 0.911 518 5160 all phecode
733.6 Costochondritis Musculoskeletal 0.997 0.892 – 1.11 0.955 357 3562 all phecode
733.8 Malunion and nonunion of fracture Musculoskeletal 0.978 0.91 – 1.05 0.548 822 8205 all phecode
733.9 Chondromalacia Musculoskeletal 1.16 0.942 – 1.43 0.162 96 960 all phecode
735 Acquired foot deformities Musculoskeletal 0.984 0.949 – 1.02 0.381 3417 29622 all phecode
735.1 Flat foot Musculoskeletal 1.03 0.947 – 1.12 0.493 620 6092 all phecode
735.2 Acquired toe deformities Musculoskeletal 0.993 0.938 – 1.05 0.821 1323 11983 all phecode
735.21 Hammer toe (acquired) Musculoskeletal 0.968 0.9 – 1.04 0.373 825 7494 all phecode
735.23 Hallux rigidus Musculoskeletal 1.01 0.911 – 1.12 0.863 405 4005 all phecode
735.3 Hallux valgus (Bunion) Musculoskeletal 0.941 0.891 – 0.993 0.0272 1470 14295 all phecode
736 Other acquired deformities of limbs Musculoskeletal 0.974 0.936 – 1.01 0.185 2763 26555 all phecode
736.1 Acquired deformities of forearm Musculoskeletal 0.835 0.684 – 1.02 0.0769 104 1033 all phecode
736.2 Acquired deformities of finger Musculoskeletal 1.08 0.939 – 1.24 0.285 215 2142 all phecode
736.3 Acquired deformities of hip Musculoskeletal 0.926 0.713 – 1.2 0.567 60 590 all phecode
736.4 Genu valgum or varum (acquired) Musculoskeletal 0.96 0.856 – 1.08 0.481 325 3247 all phecode
736.5 Acquired deformities of knee Musculoskeletal 0.994 0.871 – 1.14 0.935 246 2460 all phecode
736.6 Unequal leg length (acquired) Musculoskeletal 0.92 0.822 – 1.03 0.143 339 3365 all phecode
737 Curvature of spine Musculoskeletal 0.973 0.924 – 1.03 0.311 1566 15543 all phecode
737.1 Kyphosis (acquired) Musculoskeletal 1.03 0.938 – 1.13 0.54 479 4748 all phecode
737.2 Lordosis (acquired) Musculoskeletal 0.975 0.765 – 1.24 0.839 70 700 all phecode
737.3 Kyphoscoliosis and scoliosis Musculoskeletal 0.972 0.916 – 1.03 0.359 1203 11982 all phecode
738 Other acquired musculoskeletal deformity Musculoskeletal 0.973 0.933 – 1.01 0.2 2443 24187 all phecode
738.4 Acquired spondylolisthesis Musculoskeletal 0.963 0.903 – 1.03 0.239 1057 10542 all phecode
739 Contracture of joint Musculoskeletal 0.885 0.814 – 0.963 0.00438 621 6207 all phecode
740 Osteoarthrosis Musculoskeletal 0.992 0.972 – 1.01 0.41 16169 30268 all phecode
740.1 Osteoarthritis; localized Musculoskeletal 0.999 0.972 – 1.03 0.959 7005 27422 all phecode
740.11 Osteoarthrosis, localized, primary Musculoskeletal 0.997 0.969 – 1.03 0.835 6176 26155 all phecode
740.12 Osteoarthrosis, localized, secondary Musculoskeletal 0.98 0.906 – 1.06 0.62 713 7116 all phecode
740.2 Osteoarthrosis, generalized Musculoskeletal 1 0.953 – 1.06 0.868 1609 12092 all phecode
740.3
Osteoarthrosis involving more than one site
Osteoarthrosis involving more than one site, but not specified as generalized
 Musculoskeletal 0.937 0.842 – 1.04 0.236 373 3586 all phecode
740.9 Osteoarthrosis NOS Musculoskeletal 0.99 0.97 – 1.01 0.356 15497 30141 all phecode
741 Symptoms and disorders of the joints Musculoskeletal 0.995 0.972 – 1.02 0.709 8555 35884 all phecode
741.1 Ankylosis of joint Musculoskeletal 1.05 0.921 – 1.21 0.446 245 2445 all phecode
741.2 Stiffness of joint Musculoskeletal 1.02 0.964 – 1.08 0.471 1268 12594 all phecode
741.3 Difficulty in walking Musculoskeletal 1.02 0.977 – 1.06 0.398 2558 23116 all phecode
741.4 Joint effusions Musculoskeletal 1.01 0.966 – 1.05 0.72 2493 24199 all phecode
741.5 Hemarthrosis Musculoskeletal 1.17 0.952 – 1.44 0.134 94 937 all phecode
741.6 Villonodular synovitis Musculoskeletal 1.17 0.91 – 1.5 0.22 68 666 all phecode
742 Derangement of joint, non-traumatic Musculoskeletal 1.01 0.976 – 1.04 0.625 4404 33771 all phecode
742.1 Loose body in joint Musculoskeletal 1.2 1.02 – 1.42 0.0317 156 1554 all phecode
742.2
Pathological, developmental or recurrent
Pathological, developmental or recurrent dislocation
 Musculoskeletal 0.912 0.808 – 1.03 0.138 280 2792 all phecode
742.8 Articular cartilage disorder Musculoskeletal 1.05 0.92 – 1.19 0.48 245 2450 all phecode
742.9 Other derangement of joint Musculoskeletal 1.01 0.975 – 1.04 0.651 4107 32972 all phecode
743
Osteoporosis, osteopenia and pathological
Osteoporosis, osteopenia and pathological fracture
 Musculoskeletal 1 0.98 – 1.03 0.73 9223 36921 all phecode
743.1 Osteoporosis Musculoskeletal 0.998 0.962 – 1.04 0.926 3712 19477 all phecode
743.11 Osteoporosis NOS Musculoskeletal 0.996 0.96 – 1.03 0.846 3657 19276 all phecode
743.12 Senile osteoporosis Musculoskeletal 1.02 0.944 – 1.11 0.597 703 5804 all phecode
743.13 Other specified osteoporosis Musculoskeletal 1.03 0.914 – 1.15 0.661 321 3141 all phecode
743.2 Pathologic fracture Musculoskeletal 1.03 0.966 – 1.09 0.386 1112 10563 all phecode
743.21 Pathologic fracture of vertebrae Musculoskeletal 1.06 0.966 – 1.16 0.215 475 4629 all phecode
743.22 Pathologic fracture of femur Musculoskeletal 0.93 0.78 – 1.11 0.414 143 1391 all phecode
743.4 Stress fracture Musculoskeletal 1.05 0.946 – 1.16 0.367 407 4046 all phecode
743.9
Osteopenia or other disorder of bone and
Osteopenia or other disorder of bone and cartilage
 Musculoskeletal 1.01 0.98 – 1.03 0.619 6970 35237 all phecode
745 Pain in joint Musculoskeletal 0.992 0.974 – 1.01 0.402 19848 26918 all phecode
747 Cardiac and circulatory congenital anomalies Congenital Anomalies 0.984 0.942 – 1.03 0.482 2236 22256 all phecode
747.1 Cardiac congenital anomalies Congenital Anomalies 0.982 0.935 – 1.03 0.476 1767 17598 all phecode
747.11 Cardiac shunt/ heart septal defect Congenital Anomalies 0.928 0.856 – 1.01 0.0701 650 6497 all phecode
747.12 Valvular heart disease/ heart chambers Congenital Anomalies 1.01 0.936 – 1.09 0.811 751 7480 all phecode
747.13 Congenital anomalies of great vessels Congenital Anomalies 1.06 0.954 – 1.17 0.295 410 4090 all phecode
747.2
Congenital anomalies of peripheral vascular
Congenital anomalies of peripheral vascular system
 Congenital Anomalies 1.01 0.926 – 1.11 0.77 501 5010 all phecode
748 Anomalies of respiratory system, congenital Congenital Anomalies 0.909 0.741 – 1.11 0.358 111 1110 all phecode
749 Congenital anomalies of face and neck Congenital Anomalies 0.943 0.864 – 1.03 0.189 555 5549 all phecode
749.1 Cleft palate Congenital Anomalies 1.06 0.851 – 1.31 0.619 97 970 all phecode
749.2 Congenital anomalies of skull and face bones Congenital Anomalies 0.992 0.81 – 1.22 0.942 105 1041 all phecode
750 Digestive congenital anomalies Congenital Anomalies 1.02 0.949 – 1.09 0.638 893 8919 all phecode
750.1 Upper gastrointestinal congenital anomalies Congenital Anomalies 1.04 0.93 – 1.16 0.511 366 3655 all phecode
750.11 Esophageal atresia/tracheoesophageal fistula Congenital Anomalies 1.08 0.902 – 1.3 0.389 119 1185 all phecode
750.13 Congenital anomalies of mouth/tongue Congenital Anomalies 0.976 0.792 – 1.2 0.818 99 982 all phecode
750.14 Congenital anomalies of esophagus Congenital Anomalies 1.14 0.957 – 1.37 0.139 134 1332 all phecode
750.15 Congenital anomalies of stomach Congenital Anomalies 1.02 0.786 – 1.33 0.879 60 593 all phecode
750.2 Lower gastrointestinal congenital anomalies Congenital Anomalies 0.996 0.911 – 1.09 0.926 531 5300 all phecode
750.21 Congenital anomalies of intestine Congenital Anomalies 1.01 0.898 – 1.13 0.892 313 3129 all phecode
750.22
Congenital anomaly of gallbladder, bile ducts
Congenital anomaly of gallbladder, bile ducts, liver, pancreas
 Congenital Anomalies 0.978 0.852 – 1.12 0.754 222 2214 all phecode
751 Genitourinary congenital anomalies Congenital Anomalies 0.972 0.928 – 1.02 0.227 2008 19975 all phecode
751.1 Congenital anomalies of genital organs Congenital Anomalies 1.07 0.977 – 1.16 0.151 574 5740 all phecode
751.11 Congenital anomalies of female genital organs Congenital Anomalies 1.05 0.946 – 1.17 0.351 384 3840 all phecode
751.12 Congenital anomalies of male genital organs Congenital Anomalies 1.16 0.981 – 1.37 0.082 153 1527 all phecode
751.2 Congenital anomalies of urinary system Congenital Anomalies 0.948 0.897 – 1 0.0604 1379 13704 all phecode
751.21 Cystic kidney disease Congenital Anomalies 0.93 0.87 – 0.994 0.0315 976 9685 all phecode
751.22 Other specified congenital anomalies of kidney Congenital Anomalies 0.973 0.863 – 1.1 0.655 294 2927 all phecode
751.3 Obstructive genitourinary defect Congenital Anomalies 0.988 0.848 – 1.15 0.881 182 1809 all phecode
752 Nervous system congenital anomalies Congenital Anomalies 0.977 0.919 – 1.04 0.468 1133 11313 all phecode
752.1 Neural tube defects Congenital Anomalies 0.971 0.907 – 1.04 0.408 923 9209 all phecode
752.11 Spina bifida Congenital Anomalies 1.15 0.986 – 1.35 0.0754 176 1760 all phecode
752.2
Other specified congenital anomalies of nervous
Other specified congenital anomalies of nervous system
 Congenital Anomalies 0.99 0.865 – 1.13 0.88 232 2320 all phecode
753 Congenital anomalies of the eye Congenital Anomalies 0.969 0.84 – 1.12 0.662 207 2051 all phecode
753.1 Congenital cataract and lens anomalies Congenital Anomalies 1.04 0.801 – 1.36 0.76 58 580 all phecode
753.2 Congenital anomalies of posterior segment of eye Congenital Anomalies 1.15 0.868 – 1.52 0.333 56 546 all phecode
754 Congenital musculoskeletal deformities of spine Congenital Anomalies 0.938 0.884 – 0.996 0.036 1216 12116 all phecode
754.1 Lumbosacral spondylolysis, congenital Congenital Anomalies 1.1 0.916 – 1.32 0.303 135 1333 all phecode
754.2 Spondylolisthesis, congenital Congenital Anomalies 0.92 0.842 – 1 0.0627 558 5570 all phecode
755 Congenital anomalies of limbs Congenital Anomalies 0.984 0.912 – 1.06 0.676 747 7458 all phecode
755.1 Congenital deformities of feet Congenital Anomalies 0.981 0.881 – 1.09 0.723 368 3663 all phecode
755.4
Congenital anomalies of upper limb, including
Congenital anomalies of upper limb, including shoulder girdle
 Congenital Anomalies 1.05 0.824 – 1.35 0.675 74 740 all phecode
755.6
Other congenital anomalies of lower limb
Other congenital anomalies of lower limb, including pelvic girdle
 Congenital Anomalies 0.949 0.846 – 1.06 0.375 321 3205 all phecode
755.61 Congenital hip dysplasia and deformity Congenital Anomalies 1.01 0.866 – 1.17 0.935 185 1847 all phecode
756 Other congenital musculoskeletal anomalies Congenital Anomalies 0.966 0.913 – 1.02 0.234 1358 13579 all phecode
756.1 Congenital anomalies of abdominal wall; diaphram Congenital Anomalies 1.07 0.83 – 1.37 0.619 68 680 all phecode
756.2
Pectus and other congenital anomalies of
Pectus and other congenital anomalies of ribs/sternum
 Congenital Anomalies 1.04 0.818 – 1.33 0.73 71 694 all phecode
756.3
Congenital anomalies of muscle, tendon, fascia
Congenital anomalies of muscle, tendon, fascia, and connective tissue
 Congenital Anomalies 1.02 0.909 – 1.13 0.787 335 3346 all phecode
756.5 Congenital osteodystrophies Congenital Anomalies 0.988 0.925 – 1.06 0.719 1003 10014 all phecode
757 Congenital anomalies of the integument Congenital Anomalies 0.98 0.885 – 1.09 0.705 401 4001 all phecode
758 Chromosomal anomalies and genetic disorders Congenital Anomalies 0.963 0.829 – 1.12 0.627 185 1845 all phecode
758.1 Chromosomal anomalies Congenital Anomalies 0.975 0.817 – 1.16 0.781 135 1349 all phecode
759 Other and unspecified congenital anomalies Congenital Anomalies 0.947 0.868 – 1.03 0.221 557 5566 all phecode
759.1 Anomalies of endocrine glands, congenital Congenital Anomalies 0.829 0.65 – 1.06 0.132 71 710 all phecode
760 Back pain Symptoms 1.01 0.986 – 1.02 0.61 16037 30719 all phecode
761 Cervicalgia Symptoms 1 0.977 – 1.03 0.837 6528 39755 all phecode
763
Thoracic or lumbosacral neuritis or
Thoracic or lumbosacral neuritis or radiculitis, unspecified
 Symptoms 1 0.97 – 1.04 0.82 3657 32599 all phecode
764 Sciatica Symptoms 1.02 0.982 – 1.05 0.354 3542 32015 all phecode
765 Cervical radiculitis Symptoms 1.03 0.981 – 1.08 0.226 1799 17851 all phecode
766 Neuralgia, neuritis, and radiculitis NOS Symptoms 1.01 0.977 – 1.04 0.692 5124 37132 all phecode
767 Cervicocranial/Cervicobrachial syndrome Symptoms 1.02 0.839 – 1.23 0.871 117 1168 all phecode
769 Nonallopathic lesions NEC Symptoms 1.03 0.971 – 1.1 0.297 1131 11220 all phecode
770 Myalgia and myositis unspecified Symptoms 1.02 0.989 – 1.05 0.232 5533 34303 all phecode
771 Musculoskeletal symptoms referable to limbs Symptoms 0.97 0.941 – 1 0.0472 4799 35575 all phecode
771.1 Swelling of limb Symptoms 0.969 0.942 – 0.997 0.0292 5743 35539 all phecode
771.2 Cramp of limb Symptoms 1.02 0.956 – 1.09 0.564 1079 10568 all phecode
772 Symptoms of the muscles Symptoms 0.977 0.933 – 1.02 0.313 2042 20221 all phecode
772.1 Muscular wasting and disuse atrophy Symptoms 0.96 0.869 – 1.06 0.427 422 4199 all phecode
772.2 Spasm of muscle Symptoms 0.988 0.946 – 1.03 0.584 2299 22726 all phecode
772.3 Muscle weakness Symptoms 1.01 0.97 – 1.05 0.7 2949 28064 all phecode
772.4 Rhabdomyolysis Symptoms 1.14 0.963 – 1.35 0.129 159 1572 all phecode
772.6 Facial weakness Symptoms 0.969 0.881 – 1.07 0.525 478 4742 all phecode
780 Hypothermia/Chills Symptoms 0.983 0.891 – 1.08 0.734 453 4514 all phecode
781
Symptoms involving nervous and musculoskeletal
Symptoms involving nervous and musculoskeletal systems
 Symptoms 0.973 0.936 – 1.01 0.173 2822 26225 all phecode
781.1 Loss of height Symptoms 0.969 0.812 – 1.16 0.727 130 1269 all phecode
781.2 Abnormal posture Symptoms 0.808 0.623 – 1.05 0.107 57 567 all phecode
782.3 Edema Symptoms 0.976 0.95 – 1 0.0959 5874 36788 all phecode
782.6 Pallor and flushing Symptoms 1.04 0.975 – 1.12 0.22 927 9252 all phecode
783 Fever of unknown origin Symptoms 1 0.976 – 1.03 0.779 5733 40720 all phecode
783.1 Postprocedural fever Symptoms 0.893 0.793 – 1.01 0.0635 300 2992 all phecode
785 Abdominal pain Symptoms 1 0.983 – 1.02 0.849 16458 30297 all phecode
788 Syncope and collapse Symptoms 1.01 0.975 – 1.04 0.617 3851 35832 all phecode
789 Nausea and vomiting Symptoms 1.02 0.997 – 1.04 0.0956 10568 36098 all phecode
789.1 Persistent vomiting Symptoms 0.985 0.916 – 1.06 0.692 798 7924 all phecode
790 Nonspecific findings on examination of blood Symptoms 0.996 0.954 – 1.04 0.842 2363 22690 all phecode
790.1 Elevated sedimentation rate Symptoms 1.11 0.971 – 1.26 0.127 236 2322 all phecode
790.6 Other abnormal blood chemistry Symptoms 1.02 0.997 – 1.05 0.0825 7539 37788 all phecode
790.8 Elevated C-reactive protein (CRP) Symptoms 1.04 0.929 – 1.17 0.475 309 3075 all phecode
790.9 Abnormal arterial blood gases Symptoms 0.907 0.766 – 1.07 0.256 155 1521 all phecode
791 Gangrene Symptoms 0.971 0.863 – 1.09 0.625 313 3115 all phecode
792
Abnormal Papanicolaou smear of cervix and
Abnormal Papanicolaou smear of cervix and cervical HPV
 Genitourinary 0.986 0.947 – 1.03 0.508 2820 14872 all phecode
792.1
Papanicolaou smear of cervix or vagina with
Papanicolaou smear of cervix or vagina with atypical squamous cells
 Genitourinary 0.998 0.937 – 1.06 0.943 1100 9861 all phecode
794
Abnormal results of other function studies
Abnormal results of other function studies (bladder, pancreas, placenta, spleen, etc)
 Symptoms 1.03 0.939 – 1.13 0.528 515 5133 all phecode
795
Other and nonspecific abnormal cytological
Other and nonspecific abnormal cytological, histological and immunological findings
 Symptoms 0.984 0.941 – 1.03 0.473 2182 20242 all phecode
795.8 Abnormal tumor markers Symptoms 0.99 0.942 – 1.04 0.689 1745 15551 all phecode
795.81 Elevated carcinoembryonic antigen [CEA] Symptoms 0.978 0.755 – 1.27 0.867 61 605 all phecode
795.82 Elevated cancer antigen 125 [CA 125] Symptoms 0.984 0.85 – 1.14 0.834 201 2000 all phecode
796 Elevated prostate specific antigen [PSA] Genitourinary 1.01 0.963 – 1.06 0.674 2125 9930 all phecode
797 Shock Symptoms 1.03 0.951 – 1.13 0.428 605 6050 all phecode
797.1 Cardiogenic shock Symptoms 1.05 0.918 – 1.21 0.464 242 2420 all phecode
798 Malaise and fatigue Symptoms 1.03 1.01 – 1.05 0.0137 11539 35196 all phecode
798.1 Chronic fatigue syndrome Symptoms 1.03 0.978 – 1.08 0.287 1823 17795 all phecode
800 Fracture of lower limb Injuries & Poisonings 0.998 0.956 – 1.04 0.935 2344 22951 all phecode
800.1 Fracture of neck of femur Injuries & Poisonings 0.982 0.896 – 1.08 0.699 512 4961 all phecode
800.2 Fracture of unspecified part of femur Injuries & Poisonings 0.998 0.922 – 1.08 0.964 670 6582 all phecode
800.3 Fracture of tibia and fibula Injuries & Poisonings 1 0.934 – 1.07 0.972 898 8966 all phecode
800.4 Fracture of patella Injuries & Poisonings 0.965 0.864 – 1.08 0.53 346 3456 all phecode
801 Fracture of ankle and foot Injuries & Poisonings 0.999 0.957 – 1.04 0.948 2358 22645 all phecode
801.1 Fracture of foot Injuries & Poisonings 1.03 0.964 – 1.09 0.417 1120 11178 all phecode
802 Fracture of pelvis Injuries & Poisonings 1.13 1.01 – 1.25 0.0311 380 3765 all phecode
803 Fracture of upper limb Injuries & Poisonings 0.985 0.94 – 1.03 0.51 2051 20360 all phecode
803.1 Fracture of humerus Injuries & Poisonings 1 0.929 – 1.08 0.94 734 7322 all phecode
803.2 Fracture of radius and ulna Injuries & Poisonings 0.966 0.908 – 1.03 0.274 1112 11075 all phecode
803.21 Colles' fracture Injuries & Poisonings 0.969 0.859 – 1.09 0.611 291 2904 all phecode
803.3 Fracture of clavicle or scapula Injuries & Poisonings 0.976 0.891 – 1.07 0.602 514 5140 all phecode
804 Fracture of hand or wrist Injuries & Poisonings 0.973 0.924 – 1.03 0.308 1628 16042 all phecode
805
Fracture of vertebral column without mention of
Fracture of vertebral column without mention of spinal cord injury
 Injuries & Poisonings 1.03 0.972 – 1.09 0.33 1336 13242 all phecode
807 Fracture of ribs Injuries & Poisonings 0.997 0.921 – 1.08 0.936 683 6815 all phecode
809 Fracture of unspecified bones Injuries & Poisonings 1 0.963 – 1.04 0.978 2941 28633 all phecode
816 Cerebral laceration and contusion Injuries & Poisonings 0.743 0.562 – 0.982 0.037 54 531 all phecode
817 Concussion Injuries & Poisonings 1.01 0.948 – 1.08 0.737 1018 10149 all phecode
818 Intracranial hemorrhage (injury) Injuries & Poisonings 0.931 0.828 – 1.05 0.235 311 3104 all phecode
818.1 Subdural hemorrhage (injury) Injuries & Poisonings 0.932 0.757 – 1.15 0.506 90 895 all phecode
818.2 Subarachnoid hemorrhage (injury) Injuries & Poisonings 1.04 0.848 – 1.29 0.683 97 970 all phecode
819
Skull and face fracture and other intercranial
Skull and face fracture and other intercranial injury
 Injuries & Poisonings 0.999 0.956 – 1.04 0.953 2287 22671 all phecode
830 Dislocation Injuries & Poisonings 1.02 0.985 – 1.05 0.283 3862 34720 all phecode
835 Internal derangement of knee Injuries & Poisonings 1.01 0.969 – 1.06 0.58 2231 21628 all phecode
836 Traumatic arthropathy Injuries & Poisonings 0.957 0.871 – 1.05 0.354 496 4954 all phecode
840 Sprains and strains Injuries & Poisonings 0.99 0.965 – 1.01 0.403 7838 37998 all phecode
840.1 Muscle/tendon sprain Injuries & Poisonings 0.964 0.882 – 1.05 0.423 537 5356 all phecode
840.2 Rotator cuff (capsule) sprain Injuries & Poisonings 0.985 0.936 – 1.04 0.567 1640 16263 all phecode
840.3 Joint/ligament sprain Injuries & Poisonings 0.977 0.939 – 1.02 0.236 2875 24879 all phecode
841 Sprains and strains of back and neck Injuries & Poisonings 0.944 0.896 – 0.995 0.0308 1583 15592 all phecode
842 Other sprains and strains Injuries & Poisonings 1 0.949 – 1.06 0.899 1407 13924 all phecode
850 Hemorrhage or hematoma complicating a procedure Injuries & Poisonings 0.958 0.915 – 1 0.0643 2072 20649 all phecode
851
Complications of transplants and reattached
Complications of transplants and reattached limbs
 Injuries & Poisonings 0.977 0.94 – 1.01 0.223 2982 27545 all phecode
853 Complication of colostomy or enterostomy Injuries & Poisonings 1.05 0.951 – 1.16 0.337 460 4600 all phecode
854
Complications of cardiac/vascular device
Complications of cardiac/vascular device, implant, and graft
 Injuries & Poisonings 1.03 0.982 – 1.08 0.23 1985 19675 all phecode
855
Complication of nervous system device, implant
Complication of nervous system device, implant, and graft
 Injuries & Poisonings 1.03 0.902 – 1.17 0.698 264 2640 all phecode
856
Vascular complications of surgery and medical
Vascular complications of surgery and medical procedures
 Injuries & Poisonings 1.04 0.917 – 1.17 0.573 293 2929 all phecode
857
Mechanical complication of unspecified
Mechanical complication of unspecified genitourinary device, implant, and graft
 Injuries & Poisonings 0.941 0.889 – 0.997 0.0382 1310 13087 all phecode
858 Complication of internal orthopedic device Injuries & Poisonings 0.997 0.953 – 1.04 0.877 2213 21944 all phecode
859
Complication due to other implant and internal
Complication due to other implant and internal device
 Injuries & Poisonings 0.985 0.942 – 1.03 0.518 2110 21070 all phecode
860 Bone marrow or stem cell transplant Neoplasms 0.997 0.85 – 1.17 0.972 166 1660 all phecode
870 Open wounds of head; neck; and trunk Injuries & Poisonings 0.993 0.961 – 1.03 0.66 4117 36734 all phecode
870.1 Open wound or laceration of eye or eyelid Injuries & Poisonings 1.02 0.884 – 1.18 0.786 204 2026 all phecode
870.2 Open wound of ear Injuries & Poisonings 0.964 0.81 – 1.15 0.676 144 1437 all phecode
870.3 Other open wound of head and face Injuries & Poisonings 0.944 0.892 – 1 0.0484 1346 13301 all phecode
870.4 Open wound of nose and sinus Injuries & Poisonings 0.958 0.829 – 1.11 0.556 207 2057 all phecode
870.5 Open wound of lip and mouth Injuries & Poisonings 1.02 0.9 – 1.16 0.759 275 2724 all phecode
870.6 Open wound of neck Injuries & Poisonings 0.979 0.851 – 1.13 0.768 214 2128 all phecode
870.8 Open wound of genital organs Injuries & Poisonings 1.19 1 – 1.41 0.0483 144 1440 all phecode
871 Open wounds of extremities Injuries & Poisonings 0.99 0.956 – 1.03 0.574 3530 32903 all phecode
871.1 Open wound of hand except finger(s) Injuries & Poisonings 0.971 0.889 – 1.06 0.506 572 5701 all phecode
871.2 Open wound of finger(s) Injuries & Poisonings 1.03 0.962 – 1.1 0.408 984 9772 all phecode
871.3 Open wound of foot except toe(s) alone Injuries & Poisonings 0.988 0.899 – 1.09 0.799 490 4843 all phecode
871.4 Open wound of toe(s) Injuries & Poisonings 1 0.889 – 1.13 0.977 295 2921 all phecode
872 Traumatic amputation Injuries & Poisonings 0.997 0.913 – 1.09 0.953 551 5477 all phecode
874 Complication of amputation stump Injuries & Poisonings 0.89 0.757 – 1.05 0.16 170 1697 all phecode
875 Non-healing surgical wound Injuries & Poisonings 0.955 0.874 – 1.04 0.309 572 5720 all phecode
876
Posttraumatic wound infection not elsewhere
Posttraumatic wound infection not elsewhere classified
 Injuries & Poisonings 1.03 0.955 – 1.11 0.458 802 8003 all phecode
907 Injuries to the nervous system Injuries & Poisonings 1.08 1.01 – 1.15 0.0267 1010 10096 all phecode
910 Superficial injury, infected Injuries & Poisonings 0.997 0.825 – 1.21 0.979 119 1161 all phecode
911 Blister Injuries & Poisonings 0.906 0.802 – 1.02 0.11 302 2996 all phecode
912 Insect bite Injuries & Poisonings 0.962 0.876 – 1.06 0.413 492 4886 all phecode
913 Toxic effect of venom Injuries & Poisonings 0.993 0.888 – 1.11 0.906 337 3326 all phecode
916 Contusion Injuries & Poisonings 0.996 0.965 – 1.03 0.821 4296 38033 all phecode
930 Allergic reaction to food Injuries & Poisonings 0.922 0.856 – 0.994 0.0334 763 7596 all phecode
931
Contact dermatitis and other eczema due to
Contact dermatitis and other eczema due to plants [except food]
 Dermatologic 0.97 0.897 – 1.05 0.432 714 7072 all phecode
938 Dermatitis due to solar radiation Dermatologic 1.02 0.993 – 1.05 0.133 5567 29098 all phecode
938.1 Acute dermatitis due to solar radiation Dermatologic 0.991 0.864 – 1.14 0.901 217 2164 all phecode
938.2 Chronic dermatitis due to solar radiation Dermatologic 1.02 0.992 – 1.05 0.156 5307 28656 all phecode
939
Atopic/contact dermatitis due to other or
Atopic/contact dermatitis due to other or unspecified
 Dermatologic 1 0.978 – 1.03 0.743 6704 32389 all phecode
939.1 Contact and allergic dermatitis of eyelid Dermatologic 0.983 0.794 – 1.22 0.875 91 870 all phecode
941 Adverse reaction to serum or vaccine Injuries & Poisonings 1.1 0.939 – 1.28 0.249 188 1880 all phecode
942 Infusion and transfusion reaction Injuries & Poisonings 1.01 0.889 – 1.15 0.887 269 2688 all phecode
946 Anaphylactic shock NOS Injuries & Poisonings 0.991 0.903 – 1.09 0.853 500 4940 all phecode
947 Urticaria Dermatologic 0.979 0.921 – 1.04 0.501 1177 11454 all phecode
949 Allergies, other Injuries & Poisonings 1.01 0.983 – 1.04 0.525 7251 32350 all phecode
952
Spinal cord injury without evidence of spinal
Spinal cord injury without evidence of spinal bone injury
 Injuries & Poisonings 1.06 0.963 – 1.16 0.243 494 4940 all phecode
957 Injury to other and unspecified nerves Injuries & Poisonings 0.991 0.832 – 1.18 0.923 136 1352 all phecode
958
Certain early complications of trauma or
Certain early complications of trauma or procedure
 Injuries & Poisonings 0.978 0.922 – 1.04 0.471 1217 12158 all phecode
958.1 Postoperative shock Injuries & Poisonings 1.12 0.951 – 1.31 0.177 169 1688 all phecode
958.2 Traumatic and surgical subcutaneous emphysema Injuries & Poisonings 1.08 0.896 – 1.31 0.411 114 1140 all phecode
960 Poisoning by antibiotics Injuries & Poisonings 0.961 0.921 – 1 0.0619 2479 22087 all phecode
960.1
Adverse effects of antibacterials (not
Adverse effects of antibacterials (not penicillins)
 Injuries & Poisonings 0.989 0.885 – 1.1 0.842 342 3403 all phecode
960.2 Allergy/adverse effect of penicillin Injuries & Poisonings 0.972 0.923 – 1.02 0.273 1636 16005 all phecode
961 Poisoning by other anti-infectives Injuries & Poisonings 1.05 0.96 – 1.15 0.283 528 5234 all phecode
961.1 Poisoning/allergy of sulfonamides Injuries & Poisonings 0.973 0.913 – 1.04 0.403 1065 10347 all phecode
962 Poisoning by hormones and synthetic substitutes Injuries & Poisonings 0.983 0.913 – 1.06 0.651 803 7976 all phecode
962.1
Adrenal cortical steroids causing adverse
Adrenal cortical steroids causing adverse effects in therapeutic use
 Injuries & Poisonings 0.943 0.847 – 1.05 0.289 379 3782 all phecode
962.2
Insulins and antidiabetic agents causing
Insulins and antidiabetic agents causing adverse effects in therapeutic use
 Injuries & Poisonings 0.829 0.639 – 1.08 0.157 62 612 all phecode
962.3
Hormones and synthetic substitutes causing
Hormones and synthetic substitutes causing adverse effects in therapeutic use
 Injuries & Poisonings 1.05 0.956 – 1.16 0.301 478 4773 all phecode
963 Poisoning by primarily systemic agents Injuries & Poisonings 1.01 0.973 – 1.06 0.521 2533 24531 all phecode
963.1
Antineoplastic and immunosuppressive drugs
Antineoplastic and immunosuppressive drugs causing adverse effects
 Injuries & Poisonings 1.02 0.98 – 1.07 0.308 2469 24057 all phecode
964
Poisoning by agents primarily affecting blood
Poisoning by agents primarily affecting blood constituents
 Injuries & Poisonings 1.03 0.957 – 1.11 0.404 743 7337 all phecode
964.1 Anticoagulants causing adverse effects Injuries & Poisonings 1.03 0.951 – 1.11 0.486 712 7027 all phecode
965
Poisoning by analgesics, antipyretics, and
Poisoning by analgesics, antipyretics, and antirheumatics
 Injuries & Poisonings 1.05 0.976 – 1.13 0.196 864 8601 all phecode
965.1
Opiates and related narcotics causing adverse
Opiates and related narcotics causing adverse effects in therapeutic use
 Injuries & Poisonings 1.04 0.986 – 1.1 0.15 1469 14402 all phecode
965.3
Salicylates causing adverse effects in
Salicylates causing adverse effects in therapeutic use
 Injuries & Poisonings 1.04 0.868 – 1.25 0.651 119 1182 all phecode
966
Poisoning by anticonvulsants and
Poisoning by anticonvulsants and anti-Parkinsonism drugs
 Injuries & Poisonings 1 0.82 – 1.23 0.968 103 1006 all phecode
967
Adverse effects of sedatives or other central
Adverse effects of sedatives or other central nervous system depressants and anesthetics
 Injuries & Poisonings 0.974 0.919 – 1.03 0.373 1254 12464 all phecode
969 Poisoning by psychotropic agents Injuries & Poisonings 1.08 0.953 – 1.22 0.236 281 2797 all phecode
971
Poisoning by drugs primarily affecting the
Poisoning by drugs primarily affecting the autonomic nervous system
 Injuries & Poisonings 0.847 0.658 – 1.09 0.199 67 643 all phecode
972
Poisoning by agents primarily affecting the
Poisoning by agents primarily affecting the cardiovascular system
 Injuries & Poisonings 1.01 0.899 – 1.14 0.831 288 2858 all phecode
972.1
Cardiac rhythm regulators causing adverse
Cardiac rhythm regulators causing adverse effects in therapeutic use
 Injuries & Poisonings 1.05 0.833 – 1.33 0.666 80 776 all phecode
972.6 Antihypertensive agents causing adverse effects Injuries & Poisonings 0.868 0.712 – 1.06 0.159 104 1034 all phecode
974
Poisoning by water, mineral, and uric acid
Poisoning by water, mineral, and uric acid metabolism drugs
 Injuries & Poisonings 1.08 0.89 – 1.31 0.433 113 1130 all phecode
975
Poisoning by agents primarily acting on the
Poisoning by agents primarily acting on the smooth and skeletal muscles and respiratory system
 Injuries & Poisonings 0.893 0.713 – 1.12 0.324 81 810 all phecode
976
Poisoning by agents primarily affecting skin &
Poisoning by agents primarily affecting skin & mucous membrane, ophthalmological, otorhinolaryngological, & dental drugs
 Injuries & Poisonings 1.27 0.988 – 1.62 0.0618 71 703 all phecode
977 Personal history of allergy to medicinal agents Injuries & Poisonings 0.976 0.929 – 1.03 0.342 1763 16599 all phecode
979 Adverse drug events and drug allergies Injuries & Poisonings 1.03 0.997 – 1.07 0.0737 3448 30885 all phecode
980
Encounter for long-term (current) use of
Encounter for long-term (current) use of antibiotics
 Infectious Diseases 0.95 0.899 – 1 0.0677 1391 13877 all phecode
985 Toxic effect of other metals Injuries & Poisonings 1.38 1.04 – 1.84 0.0255 57 564 all phecode
989
Toxic effect of other substances, chiefly
Toxic effect of other substances, chiefly nonmedicinal as to source
 Injuries & Poisonings 0.932 0.775 – 1.12 0.451 129 1275 all phecode
990 Effects radiation NOS Injuries & Poisonings 1.01 0.973 – 1.04 0.721 3927 31223 all phecode
994 Sepsis and SIRS Injuries & Poisonings 0.986 0.944 – 1.03 0.529 2192 21710 all phecode
994.1 Systemic inflammatory response syndrome (SIRS) Injuries & Poisonings 0.993 0.879 – 1.12 0.91 291 2910 all phecode
994.2 Sepsis Injuries & Poisonings 0.985 0.941 – 1.03 0.503 2086 20666 all phecode
994.21 Septic shock Injuries & Poisonings 0.972 0.896 – 1.06 0.502 627 6260 all phecode
008 Intestinal infection Infectious Diseases 1 0.942 – 1.07 0.933 1214 5969 exclusion phecode
008.5 Bacterial enteritis Infectious Diseases 1.06 0.965 – 1.17 0.215 510 2623 exclusion phecode
008.52 Intestinal infection due to C. difficile Infectious Diseases 1.09 0.977 – 1.22 0.124 397 2047 exclusion phecode
008.6 Viral Enteritis Infectious Diseases 1 0.89 – 1.13 0.957 359 1633 exclusion phecode
010 Tuberculosis Infectious Diseases 1.01 0.794 – 1.28 0.959 80 466 exclusion phecode
031 Diseases due to other mycobacteria Infectious Diseases 0.922 0.658 – 1.29 0.637 40 184 exclusion phecode
038 Septicemia Infectious Diseases 1.08 1.01 – 1.16 0.0208 1053 4659 exclusion phecode
038.1 Gram negative septicemia Infectious Diseases 1.04 0.908 – 1.18 0.595 276 1157 exclusion phecode
038.2 Gram positive septicemia Infectious Diseases 0.974 0.772 – 1.23 0.823 106 482 exclusion phecode
038.3 Bacteremia Infectious Diseases 1.09 0.991 – 1.19 0.0761 573 2429 exclusion phecode
041 Bacterial infection NOS Infectious Diseases 1.04 0.987 – 1.09 0.149 2016 7043 exclusion phecode
041.1 Staphylococcus infections Infectious Diseases 1.05 0.961 – 1.15 0.278 588 3190 exclusion phecode
041.11 Methicillin sensitive Staphylococcus aureus Infectious Diseases 1.05 0.936 – 1.18 0.402 362 1830 exclusion phecode
041.12 Methicillin resistant Staphylococcus aureus Infectious Diseases 1.02 0.891 – 1.17 0.77 256 1459 exclusion phecode
041.2 Streptococcus infection Infectious Diseases 1 0.923 – 1.09 0.917 660 3108 exclusion phecode
041.21 Rheumatic fever / chorea Infectious Diseases 1.07 0.846 – 1.36 0.556 77 495 exclusion phecode
041.4 E. coli Infectious Diseases 1.06 0.956 – 1.17 0.275 481 2254 exclusion phecode
041.8 H. pylori Infectious Diseases 0.929 0.73 – 1.18 0.552 84 501 exclusion phecode
041.9 Infection with drug-resistant microorganisms Infectious Diseases 1.09 0.912 – 1.29 0.357 167 713 exclusion phecode
053 Herpes zoster Infectious Diseases 0.979 0.897 – 1.07 0.634 635 2754 exclusion phecode
053.1 Herpes zoster with nervous system complications Infectious Diseases 0.856 0.669 – 1.1 0.218 89 383 exclusion phecode
054 Herpes simplex Infectious Diseases 1.01 0.916 – 1.11 0.88 542 2601 exclusion phecode
070 Viral hepatitis Infectious Diseases 0.934 0.818 – 1.07 0.318 269 1416 exclusion phecode
070.1 Viral hepatitis A Infectious Diseases 0.737 0.475 – 1.14 0.173 22 157 exclusion phecode
070.2 Viral hepatitis B Infectious Diseases 0.99 0.76 – 1.29 0.941 69 338 exclusion phecode
070.3 Viral hepatitis C Infectious Diseases 0.92 0.783 – 1.08 0.313 179 886 exclusion phecode
070.4 Chronic hepatitis Infectious Diseases 1 0.79 – 1.28 0.969 87 339 exclusion phecode
070.9 Hepatitis NOS Infectious Diseases 0.932 0.832 – 1.05 0.229 355 1924 exclusion phecode
071 Human immunodeficiency virus [HIV] disease Infectious Diseases 1.05 0.806 – 1.38 0.703 58 266 exclusion phecode
071.1 HIV infection, symptomatic Infectious Diseases 1.23 0.895 – 1.69 0.202 48 209 exclusion phecode
078 Viral warts & HPV Infectious Diseases 0.998 0.938 – 1.06 0.959 1270 4660 exclusion phecode
079 Viral infection Infectious Diseases 1.01 0.959 – 1.05 0.815 2623 5564 exclusion phecode
079.1 Varicella infection Infectious Diseases 0.99 0.933 – 1.05 0.736 1417 5081 exclusion phecode
079.2 Infectious mononucleosis Infectious Diseases 1.04 0.811 – 1.33 0.766 83 420 exclusion phecode
079.9 Viremia, NOS Infectious Diseases 1.12 0.996 – 1.25 0.0597 402 1449 exclusion phecode
080 Postoperative infection Infectious Diseases 1.03 0.95 – 1.11 0.507 735 4968 exclusion phecode
081
Infection/inflammation of internal prosthetic
Infection/inflammation of internal prosthetic device; implant; and graft
 Infectious Diseases 1.07 0.976 – 1.18 0.147 508 3016 exclusion phecode
090
Sexually transmitted infections (not HIV or
Sexually transmitted infections (not HIV or hepatitis)
 Infectious Diseases 1.07 0.954 – 1.19 0.259 364 2162 exclusion phecode
110 Dermatophytosis / Dermatomycosis Infectious Diseases 0.999 0.945 – 1.06 0.976 1708 5487 exclusion phecode
110.1 Dermatophytosis Infectious Diseases 0.991 0.936 – 1.05 0.769 1602 5067 exclusion phecode
110.11 Dermatophytosis of nail Infectious Diseases 1.03 0.963 – 1.1 0.384 1103 3455 exclusion phecode
110.12 Althete's foot Infectious Diseases 1.03 0.929 – 1.14 0.584 468 1839 exclusion phecode
110.13 Dermatophytosis of the body Infectious Diseases 0.96 0.85 – 1.08 0.508 340 1572 exclusion phecode
110.2 Dermatomycoses Infectious Diseases 1.03 0.865 – 1.22 0.768 153 785 exclusion phecode
112 Candidiasis Infectious Diseases 1.06 1 – 1.13 0.0515 1296 5197 exclusion phecode
112.3 Candidiasis of skin and nails Infectious Diseases 0.949 0.83 – 1.08 0.438 269 1195 exclusion phecode
117 Mycoses Infectious Diseases 1.03 0.887 – 1.2 0.69 212 1115 exclusion phecode
117.1 Histoplasmosis Infectious Diseases 0.925 0.58 – 1.48 0.746 20 160 exclusion phecode
117.4 Aspergillosis Infectious Diseases 1.31 0.962 – 1.79 0.086 55 271 exclusion phecode
130 Spirochetal infection Infectious Diseases 0.883 0.661 – 1.18 0.4 60 301 exclusion phecode
130.1 Lyme disease Infectious Diseases 1.02 0.708 – 1.47 0.913 38 203 exclusion phecode
131 Protozoan infection Infectious Diseases 0.633 0.362 – 1.11 0.11 17 109 exclusion phecode
132 Infestation (lice, mites) Infectious Diseases 0.812 0.634 – 1.04 0.1 73 401 exclusion phecode
134 Helminthiases Infectious Diseases 0.849 0.583 – 1.24 0.392 31 156 exclusion phecode
134.1 Intestinal helminthiases Infectious Diseases 0.934 0.545 – 1.6 0.803 18 114 exclusion phecode
136 Other infectious and parasitic diseases Infectious Diseases 1.01 0.949 – 1.08 0.72 1123 6410 exclusion phecode
145 Cancer of mouth Neoplasms 0.955 0.822 – 1.11 0.549 176 2974 exclusion phecode
145.1 Cancer of lip Neoplasms 0.73 0.391 – 1.36 0.322 9 130 exclusion phecode
145.2 Cancer of tongue Neoplasms 0.903 0.707 – 1.15 0.413 65 1291 exclusion phecode
145.3 Cancer of major salivary glands Neoplasms 1.01 0.767 – 1.34 0.931 54 741 exclusion phecode
145.4 Cancer of the gums Neoplasms 0.45 0.245 – 0.826 0.00991 12 321 exclusion phecode
145.5 Cancer of the mouth floor Neoplasms 1.15 0.772 – 1.72 0.484 18 383 exclusion phecode
149 Cancer of larynx, pharynx, nasal cavities Neoplasms 0.929 0.789 – 1.09 0.373 152 2619 exclusion phecode
149.1 Cancer of oropharynx Neoplasms 0.94 0.713 – 1.24 0.661 53 746 exclusion phecode
149.2 Cancer of nasopharynx Neoplasms 1.2 0.707 – 2.05 0.495 13 204 exclusion phecode
149.3 Cancer of hypopharynx Neoplasms 1.08 0.6 – 1.96 0.791 8 177 exclusion phecode
149.4 Cancer of larynx Neoplasms 0.82 0.599 – 1.12 0.216 42 796 exclusion phecode
149.5
Hx of malignant neoplasm of oral cavity and
Hx of malignant neoplasm of oral cavity and pharynx
 Neoplasms 0.864 0.699 – 1.07 0.179 85 1120 exclusion phecode
149.9 Cancer of of nasal cavities Neoplasms 1.17 0.761 – 1.8 0.472 23 467 exclusion phecode
150 Cancer of esophagus Neoplasms 0.936 0.736 – 1.19 0.593 69 805 exclusion phecode
151 Cancer of stomach Neoplasms 1 0.816 – 1.23 0.979 93 960 exclusion phecode
153 Colorectal cancer Neoplasms 1.05 0.936 – 1.18 0.408 344 2154 exclusion phecode
153.2 Colon cancer Neoplasms 1.09 0.962 – 1.24 0.174 278 1712 exclusion phecode
153.3
Malignant neoplasm of rectum, rectosigmoid
Malignant neoplasm of rectum, rectosigmoid junction, and anus
 Neoplasms 1.01 0.862 – 1.17 0.948 186 1173 exclusion phecode
155 Cancer of liver and intrahepatic bile duct Neoplasms 1.18 0.971 – 1.44 0.096 119 908 exclusion phecode
155.1 Malignant neoplasm of liver, primary Neoplasms 1.04 0.824 – 1.3 0.757 89 643 exclusion phecode
157 Pancreatic cancer Neoplasms 1.14 0.934 – 1.4 0.194 105 933 exclusion phecode
158
Neoplasm of unspecified nature of digestive
Neoplasm of unspecified nature of digestive system
 Neoplasms 0.983 0.894 – 1.08 0.728 505 3056 exclusion phecode
159
Malignant neoplasm of other and ill-defined
Malignant neoplasm of other and ill-defined sites within the digestive organs and peritoneum
 Neoplasms 1.06 0.956 – 1.17 0.28 440 3215 exclusion phecode
159.2
Malignant neoplasm of small intestine
Malignant neoplasm of small intestine, including duodenum
 Neoplasms 1.09 0.81 – 1.47 0.569 45 409 exclusion phecode
159.3
Malignant neoplasm of gallbladder and
Malignant neoplasm of gallbladder and extrahepatic bile ducts
 Neoplasms 1.02 0.655 – 1.59 0.93 22 330 exclusion phecode
159.4
Malignant neoplasm of retroperitoneum and
Malignant neoplasm of retroperitoneum and peritoneum
 Neoplasms 0.989 0.767 – 1.27 0.931 61 497 exclusion phecode
164 Cancer of intrathoracic organs Neoplasms 0.999 0.715 – 1.4 0.997 32 266 exclusion phecode
165 Cancer within the respiratory system Neoplasms 1 0.88 – 1.13 0.994 267 2696 exclusion phecode
165.1 Cancer of bronchus; lung Neoplasms 0.97 0.848 – 1.11 0.654 238 2162 exclusion phecode
170 Cancer of bone and connective tissue Neoplasms 0.982 0.859 – 1.12 0.797 224 3471 exclusion phecode
170.1 Bone cancer Neoplasms 0.906 0.74 – 1.11 0.34 99 1447 exclusion phecode
170.2 Cancer of connective tissue Neoplasms 1 0.851 – 1.17 0.999 157 2411 exclusion phecode
172 Skin cancer Neoplasms 0.956 0.905 – 1.01 0.105 1821 6592 exclusion phecode
172.1 Melanomas of skin, dx or hx Neoplasms 0.946 0.887 – 1.01 0.089 1220 5962 exclusion phecode
172.11 Melanomas of skin Neoplasms 0.883 0.798 – 0.976 0.0151 415 4893 exclusion phecode
172.2 Other non-epithelial cancer of skin Neoplasms 0.95 0.897 – 1.01 0.0783 1641 6121 exclusion phecode
172.21 Basal cell carcinoma Neoplasms 0.983 0.917 – 1.05 0.629 1011 4915 exclusion phecode
172.22 Squamous cell carcinoma Neoplasms 1.01 0.923 – 1.1 0.867 603 3747 exclusion phecode
172.3 Carcinoma in situ of skin Neoplasms 1.05 0.945 – 1.16 0.383 426 2789 exclusion phecode
173 Neoplasm of uncertain behavior of skin Neoplasms 0.997 0.917 – 1.09 0.952 645 4064 exclusion phecode
174 Breast cancer Neoplasms 0.968 0.886 – 1.06 0.475 644 2590 exclusion phecode
174.1 Breast cancer [female] Neoplasms 0.971 0.886 – 1.06 0.531 605 2403 exclusion phecode
174.11 Malignant neoplasm of female breast Neoplasms 0.979 0.892 – 1.07 0.65 592 2376 exclusion phecode
174.3 Neoplasm of uncertain behavior of breast Neoplasms 1.13 0.862 – 1.48 0.376 54 391 exclusion phecode
175 Acquired absence of breast Neoplasms 1.08 0.919 – 1.26 0.357 182 1160 exclusion phecode
180 Cervical cancer and dysplasia Neoplasms 1.04 0.919 – 1.17 0.569 357 1919 exclusion phecode
180.1 Cervical cancer Neoplasms 1.1 0.869 – 1.4 0.422 74 719 exclusion phecode
180.3
Cervical intraepithelial neoplasia [CIN]
Cervical intraepithelial neoplasia [CIN] [Cervical dysplasia]
 Neoplasms 0.994 0.873 – 1.13 0.923 307 1441 exclusion phecode
182 Malignant neoplasm of uterus Neoplasms 1.03 0.856 – 1.23 0.788 133 1214 exclusion phecode
184 Cancer of other female genital organs Neoplasms 1.06 0.926 – 1.21 0.407 243 2012 exclusion phecode
184.1
Malignant neoplasm of ovary and other uterine
Malignant neoplasm of ovary and other uterine adnexa
 Neoplasms 1.05 0.856 – 1.28 0.655 102 982 exclusion phecode
184.11 Malignant neoplasm of ovary Neoplasms 1.08 0.855 – 1.37 0.512 74 734 exclusion phecode
184.2
Cancer of other female genital organs
Cancer of other female genital organs (excluding uterus and ovary)
 Neoplasms 0.973 0.818 – 1.16 0.76 145 1084 exclusion phecode
185 Cancer of prostate Neoplasms 0.958 0.865 – 1.06 0.413 542 2021 exclusion phecode
187 Cancer of other male genital organs Neoplasms 1.04 0.828 – 1.31 0.734 75 724 exclusion phecode
187.1
Malignant neoplasm of unspecified male genital
Malignant neoplasm of unspecified male genital organ
 Neoplasms 1.26 0.808 – 1.97 0.308 21 249 exclusion phecode
187.2 Malignant neoplasm of testis Neoplasms 1.16 0.82 – 1.64 0.403 36 355 exclusion phecode
187.8
Neoplasm of uncertain behavior of male genital
Neoplasm of uncertain behavior of male genital organs
 Neoplasms 0.77 0.488 – 1.21 0.26 24 138 exclusion phecode
189
Cancer of urinary organs (incl. kidney and
Cancer of urinary organs (incl. kidney and bladder)
 Neoplasms 1.01 0.927 – 1.11 0.792 564 4858 exclusion phecode
189.1 Cancer of kidney and renal pelvis Neoplasms 0.978 0.864 – 1.11 0.726 272 3046 exclusion phecode
189.11 Malignant neoplasm of kidney, except pelvis Neoplasms 1 0.875 – 1.15 0.987 229 2649 exclusion phecode
189.12 Malignant neoplasm of renal pelvis Neoplasms 0.909 0.681 – 1.21 0.518 45 541 exclusion phecode
189.2 Cancer of bladder Neoplasms 1.03 0.925 – 1.15 0.565 354 3303 exclusion phecode
189.21 Malignant neoplasm of bladder Neoplasms 1.03 0.914 – 1.15 0.655 313 3088 exclusion phecode
189.4 Malignant neoplasm of other urinary organs Neoplasms 1.16 0.968 – 1.38 0.108 132 1446 exclusion phecode
190 Cancer of eye Neoplasms 0.829 0.534 – 1.29 0.405 25 269 exclusion phecode
191
Manlignant and unknown neoplasms of brain and
Manlignant and unknown neoplasms of brain and nervous system
 Neoplasms 1.05 0.893 – 1.25 0.533 156 1935 exclusion phecode
191.1 Cancer of brain and nervous system Neoplasms 1.03 0.837 – 1.28 0.761 92 1242 exclusion phecode
191.11 Cancer of brain Neoplasms 1.06 0.841 – 1.34 0.609 73 1025 exclusion phecode
193 Thyroid cancer Neoplasms 1.03 0.879 – 1.21 0.702 162 1804 exclusion phecode
194 Cancer of other endocrine glands Neoplasms 1.14 0.944 – 1.37 0.177 121 1191 exclusion phecode
195 Cancer, suspected or other Neoplasms 1.03 0.981 – 1.08 0.245 3427 5196 exclusion phecode
195.1 Malignant neoplasm, other Neoplasms 1.03 0.98 – 1.08 0.257 3391 5188 exclusion phecode
195.3 Malignant neoplasm of head, face, and neck Neoplasms 0.946 0.808 – 1.11 0.49 168 1912 exclusion phecode
196 Radiotherapy Neoplasms 1.01 0.924 – 1.11 0.784 550 3273 exclusion phecode
197 Chemotherapy Neoplasms 1.06 0.989 – 1.14 0.0968 1033 4586 exclusion phecode
198 Secondary malignant neoplasm Neoplasms 1.07 0.995 – 1.16 0.0663 866 4413 exclusion phecode
198.1 Secondary malignancy of lymph nodes Neoplasms 1.08 0.985 – 1.19 0.1 482 3986 exclusion phecode
198.2 Secondary malignancy of respiratory organs Neoplasms 1.05 0.902 – 1.22 0.528 187 1946 exclusion phecode
198.3
Secondary malignant neoplasm of digestive
Secondary malignant neoplasm of digestive systems
 Neoplasms 1.03 0.87 – 1.21 0.75 151 1569 exclusion phecode
198.4 Secondary malignant neoplasm of liver Neoplasms 1.03 0.867 – 1.23 0.704 134 1459 exclusion phecode
198.5 Secondary malignancy of brain/spine Neoplasms 1.07 0.869 – 1.33 0.514 89 1150 exclusion phecode
198.6 Secondary malignancy of bone Neoplasms 1.16 0.987 – 1.37 0.0718 161 1559 exclusion phecode
198.7 Secondary malignant neoplasm of skin Neoplasms 1.03 0.788 – 1.34 0.84 52 691 exclusion phecode
199 Neoplasm of uncertain behavior Neoplasms 1.05 0.983 – 1.11 0.153 1372 5086 exclusion phecode
199.4 Neurofibromatosis Neoplasms 1.51 0.846 – 2.71 0.163 11 156 exclusion phecode
200 Myeloproliferative disease Neoplasms 1.08 0.973 – 1.2 0.152 441 2412 exclusion phecode
200.1 Polycythemia vera Neoplasms 1.13 0.924 – 1.37 0.241 117 527 exclusion phecode
201 Hodgkin's disease Neoplasms 1.03 0.783 – 1.35 0.836 57 345 exclusion phecode
202 Cancer of other lymphoid, histiocytic tissue Neoplasms 0.99 0.889 – 1.1 0.854 378 3215 exclusion phecode
202.2 Non-Hodgkins lymphoma Neoplasms 0.974 0.865 – 1.1 0.657 314 2764 exclusion phecode
202.21 Nodular lymphoma Neoplasms 0.939 0.799 – 1.1 0.447 158 1411 exclusion phecode
202.22 Reticulosarcoma Neoplasms 1.13 0.833 – 1.54 0.423 43 375 exclusion phecode
202.24 Large cell lymphoma Neoplasms 1.42 1.02 – 1.98 0.0391 36 342 exclusion phecode
204 Leukemia Neoplasms 1.04 0.906 – 1.2 0.57 240 1578 exclusion phecode
204.1 Lymphoid leukemia Neoplasms 0.992 0.764 – 1.29 0.952 63 517 exclusion phecode
204.11 Lymphoid leukemia, acute Neoplasms 1.04 0.695 – 1.55 0.855 27 158 exclusion phecode
204.12 Lymphoid leukemia, chronic Neoplasms 0.996 0.737 – 1.35 0.981 46 386 exclusion phecode
204.2 Myeloid leukemia Neoplasms 1.14 0.929 – 1.4 0.21 121 663 exclusion phecode
204.21 Myeloid leukemia, acute Neoplasms 1.05 0.802 – 1.37 0.722 72 389 exclusion phecode
204.22 Myeloid leukemia, chronic Neoplasms 1.15 0.747 – 1.77 0.528 23 135 exclusion phecode
204.4 Multiple myeloma Neoplasms 0.917 0.718 – 1.17 0.49 77 503 exclusion phecode
208 Benign neoplasm of colon Neoplasms 0.995 0.952 – 1.04 0.804 3725 5595 exclusion phecode
209 Neuroendocrine tumors Neoplasms 1.11 0.859 – 1.43 0.432 63 546 exclusion phecode
210 Benign neoplasm of lip, oral cavity, and pharynx Neoplasms 0.938 0.832 – 1.06 0.295 295 3630 exclusion phecode
211
Benign neoplasm of other parts of digestive
Benign neoplasm of other parts of digestive system
 Neoplasms 1.01 0.96 – 1.05 0.816 2509 6533 exclusion phecode
212
Benign neoplasm of respiratory and
Benign neoplasm of respiratory and intrathoracic organs
 Neoplasms 1.08 0.968 – 1.2 0.175 391 3505 exclusion phecode
213 Benign neoplasm of bone and articular cartilage Neoplasms 0.948 0.842 – 1.07 0.375 332 2266 exclusion phecode
214 Lipoma Neoplasms 1.08 0.974 – 1.19 0.148 459 2915 exclusion phecode
214.1 Lipoma of skin and subcutaneous tissue Neoplasms 1.07 0.946 – 1.22 0.268 280 1774 exclusion phecode
215
Other benign neoplasm of connective and other
Other benign neoplasm of connective and other soft tissue
 Neoplasms 0.978 0.917 – 1.04 0.512 1054 7625 exclusion phecode
216 Benign neoplasm of skin Neoplasms 0.966 0.926 – 1.01 0.112 3606 5974 exclusion phecode
216.1 Screening for malignant neoplasms of the skin Neoplasms 0.793 0.604 – 1.04 0.0947 68 309 exclusion phecode
217 Vascular hamartomas and non-neoplastic nevi Neoplasms 0.921 0.844 – 1 0.0622 645 3218 exclusion phecode
217.1 Nevus, non-neoplastic Neoplasms 0.916 0.839 – 1 0.0503 623 3080 exclusion phecode
218 Benign neoplasm of uterus Neoplasms 0.913 0.852 – 0.979 0.011 1199 2769 exclusion phecode
218.1 Uterine leiomyoma Neoplasms 0.863 0.782 – 0.952 0.00325 494 2563 exclusion phecode
218.2 Other benign neoplasm of uterus Neoplasms 0.901 0.835 – 0.973 0.00748 967 2696 exclusion phecode
220 Benign neoplasm of ovary Neoplasms 0.923 0.797 – 1.07 0.287 206 1249 exclusion phecode
221 Benign neoplasm of other female genital organs Neoplasms 0.897 0.809 – 0.994 0.0385 445 2224 exclusion phecode
222 Benign neoplasm of male genital organs Neoplasms 0.966 0.855 – 1.09 0.574 297 2486 exclusion phecode
223
Benign neoplasm of kidney and other urinary
Benign neoplasm of kidney and other urinary organs
 Neoplasms 1.07 0.95 – 1.2 0.275 370 1867 exclusion phecode
224 Benign neoplasm of eye Neoplasms 0.964 0.848 – 1.1 0.579 283 1709 exclusion phecode
224.1 Benign neoplasm of eye, uveal Neoplasms 0.986 0.861 – 1.13 0.832 257 1504 exclusion phecode
225
Benign neoplasm of brain and other parts of
Benign neoplasm of brain and other parts of nervous system
 Neoplasms 0.969 0.84 – 1.12 0.667 204 2269 exclusion phecode
225.1
Benign neoplasm of brain, cranial nerves
Benign neoplasm of brain, cranial nerves, meninges
 Neoplasms 1.03 0.871 – 1.22 0.726 145 1751 exclusion phecode
225.2 Benign neoplasm of spinal cord, meninges Neoplasms 0.841 0.641 – 1.1 0.213 58 537 exclusion phecode
226 Benign neoplasm of thyroid glands Neoplasms 1.03 0.92 – 1.16 0.571 312 2658 exclusion phecode
227
Benign neoplasm of other endocrine glands and
Benign neoplasm of other endocrine glands and related structures
 Neoplasms 1.07 0.959 – 1.21 0.217 327 3275 exclusion phecode
227.1 Benign neoplasm of adrenal gland Neoplasms 1.26 1.05 – 1.51 0.0127 137 1018 exclusion phecode
227.2 Benign neoplasm of parathyroid gland Neoplasms 1.06 0.886 – 1.28 0.511 133 1391 exclusion phecode
227.3
Benign neoplasm of pituitary gland and
Benign neoplasm of pituitary gland and craniopharyngeal duct (pouch)
 Neoplasms 0.991 0.774 – 1.27 0.943 63 870 exclusion phecode
228 Hemangioma and lymphangioma, any site Neoplasms 0.992 0.917 – 1.07 0.849 709 4626 exclusion phecode
228.1 Hemangioma of skin and subcutaneous tissue Neoplasms 0.923 0.837 – 1.02 0.105 494 3047 exclusion phecode
229 Benign neoplasm of unspecified sites Neoplasms 1.03 0.968 – 1.09 0.355 1244 7465 exclusion phecode
229.1 Benign neoplasm of lymph nodes Neoplasms 1.05 0.973 – 1.14 0.204 724 6719 exclusion phecode
240 Simple and unspecified goiter Endocrine/metabolic 1 0.891 – 1.13 0.978 337 2007 exclusion phecode
241 Nontoxic nodular goiter Endocrine/metabolic 0.98 0.909 – 1.06 0.605 828 4383 exclusion phecode
241.1 Nontoxic uninodular goiter Endocrine/metabolic 0.987 0.908 – 1.07 0.756 663 3845 exclusion phecode
241.2 Nontoxic multinodular goiter Endocrine/metabolic 1.01 0.903 – 1.12 0.922 383 2424 exclusion phecode
242 Thyrotoxicosis with or without goiter Endocrine/metabolic 0.99 0.898 – 1.09 0.842 466 2750 exclusion phecode
242.1 Graves' disease Endocrine/metabolic 0.981 0.823 – 1.17 0.826 137 1024 exclusion phecode
242.2 Toxic multinodular goiter Endocrine/metabolic 1.36 0.947 – 1.95 0.0965 36 262 exclusion phecode
242.3 Exophthalmos Endocrine/metabolic 1.11 0.883 – 1.4 0.369 79 577 exclusion phecode
242.31 Thyrotoxic exophthalmos Endocrine/metabolic 0.74 0.512 – 1.07 0.111 33 262 exclusion phecode
244 Hypothyroidism Endocrine/metabolic 0.992 0.941 – 1.04 0.748 2072 6377 exclusion phecode
244.1 Secondary hypothyroidism Endocrine/metabolic 0.984 0.888 – 1.09 0.761 402 3305 exclusion phecode
244.2 Acquired hypothyroidism Endocrine/metabolic 1.09 0.987 – 1.21 0.0891 441 2531 exclusion phecode
244.4 Hypothyroidism NOS Endocrine/metabolic 0.986 0.935 – 1.04 0.604 1995 6295 exclusion phecode
245 Thyroiditis Endocrine/metabolic 1.01 0.889 – 1.15 0.855 260 1745 exclusion phecode
245.2 Chronic thyroiditis Endocrine/metabolic 1.03 0.89 – 1.19 0.704 217 1448 exclusion phecode
245.21 Chronic lymphocytic thyroiditis Endocrine/metabolic 1.02 0.88 – 1.17 0.83 216 1447 exclusion phecode
246 Other disorders of thyroid Endocrine/metabolic 0.971 0.915 – 1.03 0.325 1482 5893 exclusion phecode
246.2 Thyroid cyst Endocrine/metabolic 0.812 0.545 – 1.21 0.303 31 197 exclusion phecode
246.7 Abnormal results of function study of thyroid Endocrine/metabolic 1.03 0.923 – 1.15 0.591 354 1926 exclusion phecode
249 Secondary diabetes mellitus Endocrine/metabolic 1.06 0.951 – 1.17 0.301 691 1087 exclusion phecode
250 Diabetes mellitus Endocrine/metabolic 1.05 1 – 1.1 0.0388 5139 4378 exclusion phecode
250.1 Type 1 diabetes Endocrine/metabolic 1.03 0.946 – 1.13 0.457 1559 1539 exclusion phecode
250.11 Type 1 diabetes with ketoacidosis Endocrine/metabolic 0.937 0.739 – 1.19 0.593 175 146 exclusion phecode
250.12 Type 1 diabetes with renal manifestations Endocrine/metabolic 0.916 0.773 – 1.09 0.313 391 391 exclusion phecode
250.13 Type 1 diabetes with ophthalmic manifestations Endocrine/metabolic 1.04 0.89 – 1.22 0.603 566 411 exclusion phecode
250.14 Type 1 diabetes with neurological manifestations Endocrine/metabolic 1.02 0.865 – 1.21 0.8 462 364 exclusion phecode
250.15
Diabetes type 1 with peripheral circulatory
Diabetes type 1 with peripheral circulatory disorders
 Endocrine/metabolic 0.877 0.654 – 1.17 0.378 123 117 exclusion phecode
250.2 Type 2 diabetes Endocrine/metabolic 1.07 1.01 – 1.12 0.0161 3804 4047 exclusion phecode
250.21 Type 2 diabetes with ketoacidosis Endocrine/metabolic 1.01 0.8 – 1.28 0.926 181 181 exclusion phecode
250.22 Type 2 diabetes with renal manifestations Endocrine/metabolic 1.1 1.01 – 1.19 0.0217 1254 1797 exclusion phecode
250.23 Type 2 diabetes with ophthalmic manifestations Endocrine/metabolic 0.976 0.888 – 1.07 0.614 1123 1301 exclusion phecode
250.24 Type 2 diabetes with neurological manifestations Endocrine/metabolic 1.08 1 – 1.17 0.0375 1590 2173 exclusion phecode
250.25
Diabetes type 2 with peripheral circulatory
Diabetes type 2 with peripheral circulatory disorders
 Endocrine/metabolic 1.09 0.973 – 1.23 0.134 593 876 exclusion phecode
250.3 Insulin pump user Endocrine/metabolic 1.09 1.02 – 1.17 0.017 2021 2716 exclusion phecode
250.4 Abnormal glucose Endocrine/metabolic 1.05 0.994 – 1.1 0.0848 3800 4234 exclusion phecode
250.41 Impaired fasting glucose Endocrine/metabolic 1 0.92 – 1.09 0.958 833 2258 exclusion phecode
250.42 Other abnormal glucose Endocrine/metabolic 1.05 1 – 1.11 0.049 3471 4153 exclusion phecode
250.5 Glycosuria or Acetonuria Endocrine/metabolic 0.894 0.648 – 1.23 0.494 63 166 exclusion phecode
250.6 Polyneuropathy in diabetes Endocrine/metabolic 1.05 0.962 – 1.14 0.299 1388 1776 exclusion phecode
250.7 Diabetic retinopathy Endocrine/metabolic 0.996 0.926 – 1.07 0.923 1153 2114 exclusion phecode
251 Other disorders of pancreatic internal secretion Endocrine/metabolic 1.03 0.933 – 1.14 0.564 510 1961 exclusion phecode
251.1 Hypoglycemia Endocrine/metabolic 1.1 0.985 – 1.24 0.0877 653 1107 exclusion phecode
252 Disorders of parathyroid gland Endocrine/metabolic 1.07 0.989 – 1.16 0.093 752 3989 exclusion phecode
252.1 Hyperparathyroidism Endocrine/metabolic 1.09 1 – 1.18 0.0455 702 3700 exclusion phecode
252.2 Hypoparathyroidism Endocrine/metabolic 1.08 0.906 – 1.3 0.377 136 871 exclusion phecode
253
Disorders of the pituitary gland and its
Disorders of the pituitary gland and its hypothalamic control
 Endocrine/metabolic 1.04 0.906 – 1.18 0.609 242 1739 exclusion phecode
253.1 Pituitary hyperfunction Endocrine/metabolic 1.05 0.817 – 1.34 0.715 69 537 exclusion phecode
253.11 Acromegaly and gigantism Endocrine/metabolic 1.29 0.763 – 2.18 0.342 12 144 exclusion phecode
253.2 Pituitary hypofunction Endocrine/metabolic 1.14 0.842 – 1.54 0.4 45 419 exclusion phecode
253.3 Diabetes insipidus Endocrine/metabolic 1.04 0.696 – 1.55 0.853 33 191 exclusion phecode
253.4 Anterior pituitary disorders Endocrine/metabolic 0.851 0.621 – 1.17 0.316 48 309 exclusion phecode
253.7 Other disorders of neurohypophysis Endocrine/metabolic 1.14 0.842 – 1.55 0.392 40 201 exclusion phecode
255 Disorders of adrenal glands Endocrine/metabolic 1.01 0.918 – 1.12 0.777 459 2954 exclusion phecode
255.1 Adrenal hyperfunction Endocrine/metabolic 1 0.828 – 1.22 0.961 118 715 exclusion phecode
255.11 Cushing's syndrome Endocrine/metabolic 1.02 0.758 – 1.38 0.886 48 361 exclusion phecode
255.12 Hyperaldosteronism Endocrine/metabolic 1.13 0.823 – 1.56 0.444 42 270 exclusion phecode
255.2 Adrenal hypofunction Endocrine/metabolic 1.12 0.964 – 1.31 0.138 194 1232 exclusion phecode
255.21 Glucocorticoid deficiency Endocrine/metabolic 1.09 0.934 – 1.28 0.269 185 1168 exclusion phecode
256 Ovarian dysfunction Endocrine/metabolic 0.92 0.822 – 1.03 0.144 387 1873 exclusion phecode
256.4 Polycystic ovaries Endocrine/metabolic 0.943 0.824 – 1.08 0.394 264 1315 exclusion phecode
257 Testicular dysfunction Endocrine/metabolic 0.978 0.882 – 1.09 0.677 460 1943 exclusion phecode
257.1 Testicular hypofunction Endocrine/metabolic 0.986 0.888 – 1.1 0.798 447 1876 exclusion phecode
258 Iatrogenic endocrine disorders Endocrine/metabolic 1.12 0.772 – 1.63 0.551 34 227 exclusion phecode
258.1 Postablative ovarian failure Endocrine/metabolic 0.999 0.701 – 1.42 0.995 38 180 exclusion phecode
259 Other endocrine disorders Endocrine/metabolic 1.05 0.939 – 1.17 0.406 388 2138 exclusion phecode
260 Protein-calorie malnutrition Endocrine/metabolic 1.12 1.04 – 1.21 0.00187 888 4113 exclusion phecode
260.1 Cachexia Endocrine/metabolic 1.25 0.997 – 1.58 0.0533 85 434 exclusion phecode
260.2 severe protein-calorie malnutrition Endocrine/metabolic 1.12 1.02 – 1.23 0.0216 504 2601 exclusion phecode
260.22 Nutritional marasmus Endocrine/metabolic 1.09 0.939 – 1.27 0.249 197 956 exclusion phecode
260.3 Adult failure to thrive Endocrine/metabolic 1.11 0.953 – 1.28 0.183 215 1006 exclusion phecode
260.6 Anorexia Endocrine/metabolic 1.04 0.916 – 1.18 0.544 299 1455 exclusion phecode
260.7 Polyphagia Endocrine/metabolic 1.2 0.762 – 1.88 0.434 28 186 exclusion phecode
261 Vitamin deficiency Endocrine/metabolic 1.01 0.962 – 1.05 0.766 3082 5515 exclusion phecode
261.1 Vitamin A deficiency Endocrine/metabolic 1.11 0.762 – 1.62 0.585 33 147 exclusion phecode
261.2 Vitamin B-complex deficiencies Endocrine/metabolic 1.06 0.94 – 1.19 0.352 345 1474 exclusion phecode
261.4 Vitamin D deficiency Endocrine/metabolic 1.01 0.963 – 1.06 0.719 2923 5517 exclusion phecode
261.41 Rickets or osteomalacia Endocrine/metabolic 1.03 0.589 – 1.82 0.905 18 76 exclusion phecode
262 Mineral deficiency NEC Endocrine/metabolic 1.05 0.959 – 1.16 0.277 583 2068 exclusion phecode
263 Other nutritional deficiency Endocrine/metabolic 1.01 0.929 – 1.11 0.763 629 2700 exclusion phecode
264 Lack of normal physiological development Endocrine/metabolic 1.17 0.913 – 1.5 0.214 87 362 exclusion phecode
264.2 Failure to thrive (childhood) Endocrine/metabolic 1.01 0.735 – 1.38 0.958 40 188 exclusion phecode
264.9
Lack of normal physiological development
Lack of normal physiological development, unspecified
 Endocrine/metabolic 1.92 1.14 – 3.22 0.0137 31 117 exclusion phecode
269 Proteinuria Endocrine/metabolic 1.1 1.03 – 1.18 0.00652 1040 3071 exclusion phecode
270
Disorders of protein plasma/amino-acid
Disorders of protein plasma/amino-acid transport and metabolism
 Endocrine/metabolic 1.01 0.903 – 1.13 0.874 393 1961 exclusion phecode
270.1 Disturbances of amino-acid transport Endocrine/metabolic 0.84 0.61 – 1.16 0.289 42 308 exclusion phecode
270.11
Disturbances of sulphur-bearing amino-acid
Disturbances of sulphur-bearing amino-acid metabolism
 Endocrine/metabolic 0.838 0.575 – 1.22 0.359 31 259 exclusion phecode
270.2 Disorders of amino-acid metabolism Endocrine/metabolic 0.853 0.615 – 1.18 0.34 47 207 exclusion phecode
270.3 Disorders of plasma protein metabolism Endocrine/metabolic 1.06 0.933 – 1.2 0.382 321 1539 exclusion phecode
270.32 Paraproteinemia Endocrine/metabolic 1.06 0.89 – 1.26 0.518 173 844 exclusion phecode
270.33 Amyloidosis Endocrine/metabolic 1.79 1.11 – 2.9 0.0167 23 142 exclusion phecode
270.34 Alpha-1-antitrypsin deficiency Endocrine/metabolic 1.01 0.687 – 1.5 0.942 28 154 exclusion phecode
270.38
Other specified disorders of plasma protein
Other specified disorders of plasma protein metabolism
 Endocrine/metabolic 1.07 0.88 – 1.3 0.491 132 574 exclusion phecode
271
Disorders of carbohydrate transport and
Disorders of carbohydrate transport and metabolism
 Endocrine/metabolic 0.928 0.868 – 0.992 0.0287 1033 5694 exclusion phecode
271.3
Intestinal disaccharidase deficiencies and
Intestinal disaccharidase deficiencies and disaccharide malabsorption
 Endocrine/metabolic 0.931 0.869 – 0.996 0.0384 1004 5551 exclusion phecode
271.9
Other disorders of carbohydrate transport and
Other disorders of carbohydrate transport and metabolism
 Endocrine/metabolic 0.833 0.613 – 1.13 0.244 39 229 exclusion phecode
272 Disorders of lipoid metabolism Endocrine/metabolic 1.35 1.29 – 1.43 7.67e-31 5679 3855 exclusion phecode
272.1 Hyperlipidemia Endocrine/metabolic 1.36 1.29 – 1.43 2.44e-31 5668 3853 exclusion phecode
272.11 Hypercholesterolemia Endocrine/metabolic 1.57 1.46 – 1.69 2.79e-33 2064 3096 exclusion phecode
272.12 Hyperglyceridemia Endocrine/metabolic 1.36 1.24 – 1.5 2.67e-10 712 1661 exclusion phecode
272.13 Mixed hyperlipidemia Endocrine/metabolic 1.53 1.42 – 1.65 2.92e-28 1744 2534 exclusion phecode
272.9 Unspecified disorder of lipoid metabolism Endocrine/metabolic 1.38 1.1 – 1.73 0.00544 125 427 exclusion phecode
274 Gout and other crystal arthropathies Endocrine/metabolic 1.06 0.992 – 1.14 0.0854 1021 4780 exclusion phecode
274.1 Gout Endocrine/metabolic 1.07 0.997 – 1.14 0.0624 977 4652 exclusion phecode
274.11 Gouty arthropathy Endocrine/metabolic 1.06 0.965 – 1.16 0.225 565 2505 exclusion phecode
274.2 Crystal arthropathies Endocrine/metabolic 1.08 0.846 – 1.37 0.552 82 410 exclusion phecode
274.21 Chondrocalcinosis Endocrine/metabolic 1.04 0.816 – 1.33 0.743 76 380 exclusion phecode
275 Disorders of mineral metabolism Endocrine/metabolic 1.03 0.975 – 1.09 0.298 1628 7003 exclusion phecode
275.1 Disorders of iron metabolism Hematopoietic 0.776 0.607 – 0.992 0.0429 84 443 exclusion phecode
275.11 Hereditary hemochromatosis Hematopoietic 0.617 0.418 – 0.913 0.0157 34 222 exclusion phecode
275.2 Disorders of copper metabolism Endocrine/metabolic 0.978 0.657 – 1.46 0.913 30 137 exclusion phecode
275.3 Disorders of magnesium metabolism Endocrine/metabolic 1.06 0.964 – 1.18 0.217 487 2346 exclusion phecode
275.5 Disorders of calcium/phosphorus metabolism Endocrine/metabolic 1.03 0.966 – 1.09 0.386 1242 5996 exclusion phecode
275.51 Hypocalcemia Endocrine/metabolic 1.01 0.891 – 1.14 0.925 305 1668 exclusion phecode
275.53 Disorders of phosphorus metabolism Endocrine/metabolic 1.03 0.941 – 1.13 0.516 580 2623 exclusion phecode
275.6 Hypercalcemia Endocrine/metabolic 1.04 0.948 – 1.14 0.418 585 3003 exclusion phecode
276
Disorders of fluid, electrolyte, and acid-base
Disorders of fluid, electrolyte, and acid-base balance
 Endocrine/metabolic 1.06 1.01 – 1.11 0.00962 3458 6053 exclusion phecode
276.1 Electrolyte imbalance Endocrine/metabolic 1.06 1.01 – 1.11 0.0287 2564 5636 exclusion phecode
276.11 Hyperosmolality and/or hypernatremia Endocrine/metabolic 1.02 0.884 – 1.17 0.83 262 1017 exclusion phecode
276.12 Hyposmolality and/or hyponatremia Endocrine/metabolic 1.05 0.981 – 1.13 0.155 1050 3848 exclusion phecode
276.13 Hyperpotassemia Endocrine/metabolic 1.07 1.01 – 1.14 0.0224 1407 4299 exclusion phecode
276.14 Hypopotassemia Endocrine/metabolic 1.01 0.938 – 1.09 0.771 865 3516 exclusion phecode
276.4 Acid-base balance disorder Endocrine/metabolic 1.09 1.02 – 1.17 0.0144 999 3475 exclusion phecode
276.41 Acidosis Endocrine/metabolic 1.09 1.01 – 1.18 0.0237 871 3067 exclusion phecode
276.42 Alkalosis Endocrine/metabolic 1.09 0.942 – 1.26 0.248 222 885 exclusion phecode
276.5 Hypovolemia Endocrine/metabolic 1.1 1.04 – 1.17 0.000443 1733 5592 exclusion phecode
276.6 Fluid overload Endocrine/metabolic 1 0.925 – 1.09 0.916 777 2360 exclusion phecode
276.8 Polydipsia Endocrine/metabolic 1.11 0.803 – 1.54 0.525 48 243 exclusion phecode
277 Other disorders of metabolism Endocrine/metabolic 1.04 0.987 – 1.1 0.139 1698 6591 exclusion phecode
277.2
Other disorders of purine and pyrimidine
Other disorders of purine and pyrimidine metabolism
 Endocrine/metabolic 1.08 0.92 – 1.27 0.351 206 1102 exclusion phecode
277.4 Disorders of bilirubin excretion Endocrine/metabolic 1.01 0.886 – 1.15 0.902 301 1459 exclusion phecode
277.5 Other disorders of lipoid metabolism Endocrine/metabolic 0.99 0.892 – 1.1 0.846 434 2099 exclusion phecode
277.51 Lipoprotein disorders Endocrine/metabolic 0.993 0.885 – 1.11 0.903 364 1753 exclusion phecode
277.7 Dysmetabolic syndrome X Endocrine/metabolic 1.05 0.952 – 1.16 0.317 478 2058 exclusion phecode
278 Overweight, obesity and other hyperalimentation Endocrine/metabolic 0.971 0.932 – 1.01 0.16 5231 4434 exclusion phecode
278.1 Obesity Endocrine/metabolic 0.963 0.923 – 1 0.081 4572 4431 exclusion phecode
278.11 Morbid obesity Endocrine/metabolic 0.966 0.918 – 1.02 0.176 2451 4374 exclusion phecode
278.3 Localized adiposity Endocrine/metabolic 0.891 0.73 – 1.09 0.256 130 546 exclusion phecode
278.4 Abnormal weight gain Endocrine/metabolic 0.969 0.895 – 1.05 0.436 844 2845 exclusion phecode
279 Disorders involving the immune mechanism Endocrine/metabolic 1 0.944 – 1.07 0.884 1247 5013 exclusion phecode
279.1 Immunity deficiency Endocrine/metabolic 1.06 0.959 – 1.17 0.261 527 2081 exclusion phecode
279.11 Deficiency of humoral immunity Endocrine/metabolic 1.08 0.884 – 1.32 0.453 128 636 exclusion phecode
279.2 Autoimmune disease NEC Endocrine/metabolic 0.98 0.861 – 1.12 0.765 270 1441 exclusion phecode
279.7 Other immunological findings Endocrine/metabolic 1.03 0.981 – 1.09 0.221 2058 6405 exclusion phecode
279.8
Other specified disorders involving the immune
Other specified disorders involving the immune mechanism
 Endocrine/metabolic 1 0.872 – 1.15 0.96 231 1146 exclusion phecode
280 Iron deficiency anemias Hematopoietic 1.13 1.07 – 1.19 1.1e-05 1997 4825 exclusion phecode
280.1
Iron deficiency anemias, unspecified or not due
Iron deficiency anemias, unspecified or not due to blood loss
 Hematopoietic 1.12 1.06 – 1.18 4.16e-05 1938 4789 exclusion phecode
280.2
Iron deficiency anemia secondary to blood loss
Iron deficiency anemia secondary to blood loss (chronic)
 Hematopoietic 1.09 1.01 – 1.19 0.0307 781 2762 exclusion phecode
281 Other deficiency anemia Hematopoietic 1.13 0.98 – 1.31 0.0911 240 834 exclusion phecode
281.1 Megaloblastic anemia Hematopoietic 1.19 0.964 – 1.47 0.105 108 422 exclusion phecode
281.11 Pernicious anemia Hematopoietic 1.3 0.941 – 1.8 0.111 51 199 exclusion phecode
281.12 Other vitamin B12 deficiency anemia Hematopoietic 1.22 0.952 – 1.58 0.114 73 310 exclusion phecode
281.9 Deficiency anemias Hematopoietic 1.14 0.938 – 1.38 0.19 149 451 exclusion phecode
282 Hereditary hemolytic anemias Hematopoietic 1.03 0.842 – 1.26 0.78 134 557 exclusion phecode
282.8 Other hemoglobinopathies Hematopoietic 1.04 0.82 – 1.32 0.749 91 414 exclusion phecode
282.9 Other hereditary hemolytic anemias Hematopoietic 1.13 0.884 – 1.44 0.332 86 342 exclusion phecode
283 Acquired hemolytic anemias Hematopoietic 0.994 0.746 – 1.32 0.966 77 286 exclusion phecode
283.1 Autoimmune hemolytic anemias Hematopoietic 0.792 0.517 – 1.21 0.285 30 122 exclusion phecode
284 Aplastic anemia Hematopoietic 1.17 1.03 – 1.33 0.0183 314 1151 exclusion phecode
284.1 Pancytopenia Hematopoietic 1.16 1.01 – 1.34 0.0394 272 1006 exclusion phecode
285 Other anemias Hematopoietic 1.09 1.04 – 1.14 0.00013 4012 5235 exclusion phecode
285.1 Acute posthemorrhagic anemia Hematopoietic 1.14 1.07 – 1.22 6.17e-05 1210 4141 exclusion phecode
285.2 Anemia of chronic disease Hematopoietic 1.1 1.02 – 1.18 0.0121 957 3176 exclusion phecode
285.21 Anemia in chronic kidney disease Hematopoietic 1.06 0.961 – 1.17 0.245 589 1688 exclusion phecode
285.22 Anemia in neoplastic disease Hematopoietic 1.11 0.942 – 1.31 0.215 179 955 exclusion phecode
286 Coagulation defects Hematopoietic 1.08 1.02 – 1.14 0.0129 1401 5809 exclusion phecode
286.1 Congenital coagulation defects Hematopoietic 0.92 0.709 – 1.19 0.53 71 465 exclusion phecode
286.11 Von willebrand's disease Hematopoietic 1.03 0.632 – 1.67 0.909 19 157 exclusion phecode
286.12
Congenital deficiency of other clotting factors
Congenital deficiency of other clotting factors (including factor VII)
 Hematopoietic 0.9 0.632 – 1.28 0.56 36 250 exclusion phecode
286.2
Encounter for long-term (current) use of
Encounter for long-term (current) use of anticoagulants
 Hematopoietic 1.1 1.03 – 1.17 0.00261 1406 4555 exclusion phecode
286.3
Coagulation defects complicating pregnancy or
Coagulation defects complicating pregnancy or postpartum
 Hematopoietic 0.705 0.481 – 1.03 0.0738 33 216 exclusion phecode
286.4 Acquired coagulation factor deficiency Hematopoietic 0.941 0.765 – 1.16 0.566 118 492 exclusion phecode
286.5
Hemorrhagic disorder due to intrinsic
Hemorrhagic disorder due to intrinsic circulating anticoagulants
 Hematopoietic 1.13 0.854 – 1.5 0.391 61 269 exclusion phecode
286.6 Defibrination syndrome Hematopoietic 1.1 1.02 – 1.18 0.00912 892 4540 exclusion phecode
286.7 Other and unspecified coagulation defects Hematopoietic 1.09 1.02 – 1.16 0.0142 1077 5172 exclusion phecode
286.8 Hypercoagulable state Hematopoietic 1.03 0.903 – 1.19 0.624 244 1533 exclusion phecode
286.81 Primary hypercoagulable state Hematopoietic 1.02 0.888 – 1.17 0.782 234 1475 exclusion phecode
286.9 Abnormal coagulation profile Hematopoietic 1.06 0.964 – 1.17 0.23 557 2114 exclusion phecode
287 Purpura and other hemorrhagic conditions Hematopoietic 1.14 1.08 – 1.22 2.2e-05 1326 5057 exclusion phecode
287.1 Spontaneous ecchymoses Hematopoietic 1.07 0.847 – 1.36 0.563 82 401 exclusion phecode
287.3 Thrombocytopenia Hematopoietic 1.16 1.08 – 1.23 1.34e-05 1203 4696 exclusion phecode
287.31 Primary thrombocytopenia Hematopoietic 1.17 1 – 1.38 0.0489 189 1070 exclusion phecode
287.32 Secondary thrombocytopenia Hematopoietic 1.14 0.983 – 1.32 0.0827 208 1015 exclusion phecode
287.4 Qualitative platelet defects Hematopoietic 1.28 0.898 – 1.83 0.172 39 205 exclusion phecode
288 Diseases of white blood cells Hematopoietic 1.04 0.987 – 1.1 0.14 1829 6382 exclusion phecode
288.1 Decreased white blood cell count Hematopoietic 1.07 0.973 – 1.17 0.167 572 2808 exclusion phecode
288.11 Neutropenia Hematopoietic 1.07 0.957 – 1.2 0.228 378 1937 exclusion phecode
288.2 Elevated white blood cell count Hematopoietic 1.03 0.978 – 1.09 0.242 1606 6166 exclusion phecode
288.3 Eosinophilia Hematopoietic 1.11 0.831 – 1.47 0.489 48 359 exclusion phecode
289 Other diseases of blood and blood-forming organs Hematopoietic 1.04 0.954 – 1.13 0.398 713 3255 exclusion phecode
289.3
Personal history of diseases of blood and
Personal history of diseases of blood and blood-forming organs
 Hematopoietic 1.1 0.972 – 1.23 0.134 358 1665 exclusion phecode
289.4 Lymphadenitis Hematopoietic 1.04 0.975 – 1.11 0.226 1100 6068 exclusion phecode
289.5 Diseases of spleen Hematopoietic 1.12 0.942 – 1.33 0.198 168 754 exclusion phecode
289.8 Polycythemia, secondary Hematopoietic 1.07 0.884 – 1.3 0.483 126 546 exclusion phecode
289.9 Abnormality of red blood cells Hematopoietic 0.999 0.853 – 1.17 0.994 181 808 exclusion phecode
290
Delirium dementia and amnestic and other
Delirium dementia and amnestic and other cognitive disorders
 Mental Disorders 1.07 0.978 – 1.18 0.134 554 2261 exclusion phecode
290.1 Dementias Mental Disorders 1.04 0.898 – 1.21 0.593 222 1011 exclusion phecode
290.11 Alzheimer's disease Mental Disorders 1.12 0.855 – 1.46 0.418 63 297 exclusion phecode
290.12 Dementia with cerebral degenerations Mental Disorders 1.1 0.794 – 1.52 0.573 46 162 exclusion phecode
290.13 Senile dementia Mental Disorders 0.955 0.795 – 1.15 0.617 145 620 exclusion phecode
290.16 Vascular dementia Mental Disorders 0.872 0.598 – 1.27 0.476 42 157 exclusion phecode
290.2 Delirium due to conditions classified elsewhere Mental Disorders 1.09 0.964 – 1.22 0.174 338 1417 exclusion phecode
290.3
Other persistent mental disorders due to
Other persistent mental disorders due to conditions classified elsewhere
 Mental Disorders 1.05 0.934 – 1.18 0.41 340 1787 exclusion phecode
291
Other specified nonpsychotic and/or transient
Other specified nonpsychotic and/or transient mental disorders
 Mental Disorders 1.01 0.943 – 1.08 0.758 991 4769 exclusion phecode
291.1
Transient mental disorders due to conditions
Transient mental disorders due to conditions classified elsewhere
 Mental Disorders 1.16 0.889 – 1.51 0.275 64 389 exclusion phecode
291.4
Specific nonpsychotic mental disorders due to
Specific nonpsychotic mental disorders due to brain damage
 Mental Disorders 0.987 0.837 – 1.16 0.871 173 924 exclusion phecode
291.8 Alteration of consciousness Mental Disorders 1.02 0.941 – 1.1 0.676 808 3871 exclusion phecode
292 Neurological disorders Mental Disorders 1.03 0.975 – 1.08 0.318 2012 6897 exclusion phecode
292.1 Aphasia/speech disturbance Mental Disorders 0.992 0.91 – 1.08 0.857 596 3623 exclusion phecode
292.11 Aphasia Mental Disorders 1.02 0.881 – 1.18 0.778 215 1193 exclusion phecode
292.12 Symbolic dysfunction Mental Disorders 0.963 0.716 – 1.3 0.805 50 354 exclusion phecode
292.2 Mild cognitive impairment Mental Disorders 1.06 0.902 – 1.26 0.459 188 757 exclusion phecode
292.3 Memory loss Mental Disorders 1.03 0.95 – 1.12 0.468 719 3457 exclusion phecode
292.4 Altered mental status Mental Disorders 1.03 0.963 – 1.1 0.39 1049 4350 exclusion phecode
292.5 Transient alteration of awareness Mental Disorders 1.05 0.898 – 1.24 0.518 184 887 exclusion phecode
292.6 Hallucinations Mental Disorders 0.817 0.654 – 1.02 0.0765 93 401 exclusion phecode
293 Symptoms involving head and neck Mental Disorders 0.95 0.789 – 1.14 0.583 135 861 exclusion phecode
293.1
Swelling, mass, or lump in head and neck
Swelling, mass, or lump in head and neck [Space-occupying lesion, intracranial NOS]
 Mental Disorders 1.03 0.966 – 1.1 0.359 1093 7651 exclusion phecode
295 Schizophrenia and other psychotic disorders Mental Disorders 1.02 0.903 – 1.15 0.753 371 1210 exclusion phecode
295.1 Schizophrenia Mental Disorders 1.14 0.776 – 1.69 0.496 38 211 exclusion phecode
295.2 Paranoid disorders Mental Disorders 0.939 0.655 – 1.35 0.735 46 155 exclusion phecode
295.3 Psychosis Mental Disorders 1.03 0.899 – 1.17 0.7 320 1037 exclusion phecode
296 Mood disorders Mental Disorders 1.03 0.976 – 1.08 0.315 4100 2877 exclusion phecode
296.1 Bipolar Mental Disorders 1.05 0.936 – 1.18 0.398 384 1539 exclusion phecode
296.2 Depression Mental Disorders 1.03 0.979 – 1.08 0.25 3956 2877 exclusion phecode
296.22 Major depressive disorder Mental Disorders 1.02 0.971 – 1.08 0.411 3663 2874 exclusion phecode
297 Suicidal ideation or attempt Mental Disorders 1.06 0.935 – 1.2 0.361 361 1257 exclusion phecode
297.1 Suicidal ideation Mental Disorders 1.08 0.934 – 1.24 0.313 289 1042 exclusion phecode
297.2 Suicide or self-inflicted injury Mental Disorders 1.2 0.948 – 1.52 0.13 104 364 exclusion phecode
300 Anxiety disorders Mental Disorders 1.03 0.98 – 1.08 0.238 4064 2877 exclusion phecode
300.1 Anxiety disorder Mental Disorders 1.03 0.977 – 1.08 0.296 3817 2880 exclusion phecode
300.11 Generalized anxiety disorder Mental Disorders 0.979 0.919 – 1.04 0.512 1751 2820 exclusion phecode
300.12 Agorophobia, social phobia, and panic disorder Mental Disorders 1.02 0.916 – 1.14 0.698 457 1569 exclusion phecode
300.13 Phobia Mental Disorders 0.953 0.839 – 1.08 0.452 344 1373 exclusion phecode
300.3 Obsessive-compulsive disorders Mental Disorders 0.925 0.75 – 1.14 0.466 110 509 exclusion phecode
300.4 Dysthymic disorder Mental Disorders 0.963 0.887 – 1.04 0.357 849 2320 exclusion phecode
300.8 Acute reaction to stress Mental Disorders 1.03 0.87 – 1.21 0.751 198 767 exclusion phecode
300.9 Posttraumatic stress disorder Mental Disorders 0.974 0.836 – 1.14 0.741 224 1086 exclusion phecode
301 Personality disorders Mental Disorders 1.1 0.911 – 1.34 0.311 153 656 exclusion phecode
301.2 Antisocial/borderline personality disorder Mental Disorders 1.15 0.879 – 1.52 0.301 77 352 exclusion phecode
302 Sexual and gender identity disorders Mental Disorders 1.02 0.947 – 1.1 0.62 1300 2056 exclusion phecode
302.1 Decreased libido Mental Disorders 0.866 0.732 – 1.03 0.0956 183 781 exclusion phecode
303 Psychogenic and somatoform disorders Mental Disorders 1 0.945 – 1.06 0.984 2417 2780 exclusion phecode
303.1 Dissociative disorder Mental Disorders 0.844 0.597 – 1.19 0.337 42 246 exclusion phecode
303.3 Psychogenic disorder Mental Disorders 0.997 0.941 – 1.06 0.91 2332 2753 exclusion phecode
303.31
Gastrointestinal malfunction arising from
Gastrointestinal malfunction arising from mental factors
 Mental Disorders 0.903 0.755 – 1.08 0.268 152 713 exclusion phecode
303.4 Somatoform disorder Mental Disorders 0.993 0.875 – 1.13 0.919 308 1497 exclusion phecode
304 Adjustment reaction Mental Disorders 0.988 0.922 – 1.06 0.72 1351 2839 exclusion phecode
305.2 Eating disorder Mental Disorders 0.919 0.812 – 1.04 0.177 354 1266 exclusion phecode
306 Other mental disorder Mental Disorders 0.993 0.904 – 1.09 0.879 632 1995 exclusion phecode
306.1 Mental disorders durring/after pregnancy Mental Disorders 1.15 0.951 – 1.38 0.152 186 521 exclusion phecode
306.9 Tension headache Mental Disorders 0.928 0.804 – 1.07 0.302 254 1119 exclusion phecode
312 Conduct disorders Mental Disorders 0.896 0.718 – 1.12 0.333 98 469 exclusion phecode
312.3 Impulse control disorder Mental Disorders 0.662 0.431 – 1.02 0.0605 26 172 exclusion phecode
313 Pervasive developmental disorders Mental Disorders 0.92 0.83 – 1.02 0.115 437 2805 exclusion phecode
313.1 Attention deficit hyperactivity disorder Mental Disorders 0.913 0.817 – 1.02 0.107 378 2488 exclusion phecode
313.2 Tics and stuttering Mental Disorders 0.769 0.486 – 1.22 0.262 26 122 exclusion phecode
313.3 Autism Mental Disorders 0.861 0.531 – 1.39 0.541 23 106 exclusion phecode
315 Develomental delays and disorders Mental Disorders 1.07 0.941 – 1.22 0.297 269 1348 exclusion phecode
315.1 Learning disorder Mental Disorders 0.888 0.606 – 1.3 0.542 37 171 exclusion phecode
315.2 Speech and language disorder Mental Disorders 1.1 0.872 – 1.39 0.424 82 448 exclusion phecode
316 Substance addiction and disorders Mental Disorders 1.06 0.989 – 1.13 0.103 1043 5713 exclusion phecode
316.1 Polyneuropathy due to drugs Mental Disorders 1.12 0.937 – 1.33 0.216 141 1014 exclusion phecode
317 Alcohol-related disorders Mental Disorders 1.04 0.962 – 1.12 0.331 767 4157 exclusion phecode
317.1 Alcoholism Mental Disorders 1.02 0.941 – 1.11 0.575 638 3533 exclusion phecode
317.11 Alcoholic liver damage Mental Disorders 0.986 0.832 – 1.17 0.874 172 772 exclusion phecode
318 Tobacco use disorder Mental Disorders 1.04 0.994 – 1.1 0.0828 2393 6376 exclusion phecode
320 Meningitis Neurological 1.08 0.882 – 1.33 0.444 103 723 exclusion phecode
323 Encephalitis Neurological 0.867 0.659 – 1.14 0.309 57 377 exclusion phecode
323.8 Encephalitis, non-infectious Neurological 0.902 0.682 – 1.19 0.465 51 307 exclusion phecode
324 Other CNS infection and poliomyelitis Neurological 0.997 0.778 – 1.28 0.979 73 594 exclusion phecode
325
Phlebitis and thrombophlebitis of intracranial
Phlebitis and thrombophlebitis of intracranial venous sinuses
 Neurological 0.771 0.472 – 1.26 0.3 16 120 exclusion phecode
327 Sleep disorders Neurological 0.999 0.959 – 1.04 0.965 4707 4911 exclusion phecode
327.1 Hypersomnia Neurological 1 0.926 – 1.08 0.979 836 3183 exclusion phecode
327.3 Sleep apnea Neurological 1.01 0.967 – 1.06 0.606 3462 4848 exclusion phecode
327.31 Central/nonobstroctive sleep apnea Neurological 1.01 0.874 – 1.17 0.865 222 927 exclusion phecode
327.32 Obstructive sleep apnea Neurological 1 0.957 – 1.05 0.902 3078 4752 exclusion phecode
327.4 Insomnia Neurological 0.974 0.924 – 1.03 0.322 2090 4805 exclusion phecode
327.41 Organic or persistent insomnia Neurological 0.896 0.812 – 0.988 0.0278 529 2041 exclusion phecode
327.5 Parasomnia Neurological 1.01 0.886 – 1.16 0.837 265 1049 exclusion phecode
327.6 Circadian rhythm sleep disorder Neurological 0.889 0.727 – 1.09 0.252 127 547 exclusion phecode
327.7 Sleep related movement disorders Neurological 0.923 0.847 – 1.01 0.0705 644 2781 exclusion phecode
327.71 Restless legs syndrome Neurological 0.908 0.827 – 0.996 0.0414 550 2452 exclusion phecode
327.72 Sleep related leg cramps Neurological 1.17 0.778 – 1.77 0.445 38 143 exclusion phecode
331 Other cerebral degenerations Neurological 1.05 0.912 – 1.21 0.501 244 1390 exclusion phecode
331.1 Hydrocephalus Neurological 1.14 0.843 – 1.54 0.396 45 465 exclusion phecode
331.9 Cerebral degeneration, unspecified Neurological 0.965 0.819 – 1.14 0.669 196 855 exclusion phecode
332 Parkinson's disease Neurological 0.839 0.694 – 1.01 0.0682 137 829 exclusion phecode
333
Extrapyramidal disease and abnormal movement
Extrapyramidal disease and abnormal movement disorders
 Neurological 0.936 0.874 – 1 0.0607 989 5040 exclusion phecode
333.1 Essential tremor Neurological 0.918 0.809 – 1.04 0.189 276 1451 exclusion phecode
333.2 Myoclonus Neurological 1.21 0.926 – 1.59 0.16 69 299 exclusion phecode
333.4 Torsion dystonia Neurological 1.07 0.855 – 1.33 0.571 96 615 exclusion phecode
333.8 Other degenerative diseases of the basal ganglia Neurological 1.19 0.821 – 1.72 0.362 44 201 exclusion phecode
334 Degenerative disease of the spinal cord Neurological 0.934 0.82 – 1.06 0.304 260 1858 exclusion phecode
334.1 Spinocerebellar disease Neurological 0.766 0.526 – 1.12 0.164 34 161 exclusion phecode
334.2 Anterior horn cell disease Neurological 0.66 0.44 – 0.989 0.0443 26 223 exclusion phecode
334.21 Amyotrophic Lateral Sclerosis Neurological 0.698 0.434 – 1.12 0.139 20 135 exclusion phecode
335 Multiple sclerosis Neurological 0.905 0.734 – 1.12 0.349 98 674 exclusion phecode
337 Disorders of the autonomic nervous system Neurological 1.02 0.912 – 1.14 0.714 358 1845 exclusion phecode
337.1 Peripheral autonomic neuropathy Neurological 1.01 0.876 – 1.16 0.91 248 1126 exclusion phecode
338 Pain Neurological 0.995 0.955 – 1.04 0.813 5169 4494 exclusion phecode
338.1 Acute pain Neurological 1 0.959 – 1.05 0.882 3716 4460 exclusion phecode
338.2 Chronic pain Neurological 0.994 0.949 – 1.04 0.786 3366 4466 exclusion phecode
339 Other headache syndromes Neurological 0.98 0.935 – 1.03 0.396 2691 6364 exclusion phecode
340 Migraine Neurological 0.936 0.885 – 0.989 0.0191 1799 5505 exclusion phecode
340.1 Migrain with aura Neurological 0.972 0.905 – 1.04 0.429 1019 4148 exclusion phecode
341
Other demyelinating diseases of central nervous
Other demyelinating diseases of central nervous system
 Neurological 0.983 0.711 – 1.36 0.918 45 254 exclusion phecode
342 Hemiplegia Neurological 0.972 0.828 – 1.14 0.725 177 875 exclusion phecode
343 Infantile cerebral palsy Neurological 1.22 0.745 – 2.01 0.425 19 136 exclusion phecode
344 Other paralytic syndromes Neurological 1.02 0.875 – 1.18 0.824 200 1132 exclusion phecode
345 Epilepsy, recurrent seizures, convulsions Neurological 0.995 0.918 – 1.08 0.907 669 4596 exclusion phecode
345.1 Epilepsy Neurological 1.03 0.893 – 1.19 0.686 209 1332 exclusion phecode
345.11 Generalized convulsive epilepsy Neurological 0.956 0.739 – 1.23 0.728 60 399 exclusion phecode
345.12 Partial epilepsy Neurological 0.963 0.812 – 1.14 0.66 145 946 exclusion phecode
345.3 Convulsions Neurological 0.983 0.904 – 1.07 0.696 637 4339 exclusion phecode
346
Abnormal findings on study of brain and/or
Abnormal findings on study of brain and/or nervous system
 Neurological 0.758 0.562 – 1.02 0.0693 54 332 exclusion phecode
346.1
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of skull and head
 Neurological 0.982 0.891 – 1.08 0.719 467 2767 exclusion phecode
346.2
Nonspecific abnormal results of function study
Nonspecific abnormal results of function study of brain and central nervous system
 Neurological 0.741 0.508 – 1.08 0.122 38 210 exclusion phecode
346.3
Nonspecific abnormal findings in cerebrospinal
Nonspecific abnormal findings in cerebrospinal fluid
 Neurological 0.701 0.474 – 1.04 0.0758 29 186 exclusion phecode
347 Cataplexy and narcolepsy Neurological 1.1 0.741 – 1.64 0.632 25 213 exclusion phecode
348 Other conditions of brain Neurological 0.972 0.887 – 1.07 0.55 530 3263 exclusion phecode
348.2 Cerebral edema and compression of brain Neurological 0.996 0.851 – 1.17 0.958 169 1532 exclusion phecode
348.4 Cerebral cysts Neurological 0.8 0.595 – 1.08 0.14 49 416 exclusion phecode
348.7 Coma Neurological 1.19 0.933 – 1.52 0.16 79 449 exclusion phecode
348.8 Encephalopathy, not elsewhere classified Neurological 1.02 0.909 – 1.15 0.726 349 1621 exclusion phecode
348.9 Other conditions of brain, NOS Neurological 1.07 0.981 – 1.16 0.128 610 4145 exclusion phecode
349
Other and unspecified disorders of the nervous
Other and unspecified disorders of the nervous system
 Neurological 0.967 0.85 – 1.1 0.609 275 1634 exclusion phecode
350 Abnormal movement Neurological 1.01 0.964 – 1.06 0.636 2326 6954 exclusion phecode
350.1 Abnormal involuntary movements Neurological 0.988 0.927 – 1.05 0.716 1167 5629 exclusion phecode
350.2 Abnormality of gait Neurological 0.991 0.935 – 1.05 0.767 1460 5510 exclusion phecode
350.3 Lack of coordination Neurological 1.07 0.95 – 1.2 0.274 373 1959 exclusion phecode
350.5 Abnormal reflex Neurological 1.12 0.853 – 1.46 0.424 66 360 exclusion phecode
350.6 Disturbances of sensation of smell and taste Neurological 1.03 0.861 – 1.22 0.77 134 1038 exclusion phecode
351 Other peripheral nerve disorders Neurological 0.913 0.87 – 0.957 0.000182 2515 6009 exclusion phecode
352 Disorders of other cranial nerves Neurological 0.932 0.832 – 1.04 0.221 346 2885 exclusion phecode
352.1 Trigeminal nerve disorders [CN5] Neurological 0.822 0.68 – 0.993 0.042 131 850 exclusion phecode
352.2 Facial nerve disorders [CN7] Neurological 0.933 0.799 – 1.09 0.375 181 1334 exclusion phecode
353 Nerve root and plexus disorders Neurological 0.944 0.889 – 1 0.0615 1337 5759 exclusion phecode
353.1 Nerve plexus lesions Neurological 0.951 0.754 – 1.2 0.673 89 686 exclusion phecode
353.2 Nerve root lesions Neurological 0.955 0.677 – 1.35 0.794 37 250 exclusion phecode
355 Complex regional/central pain syndrome Neurological 0.972 0.811 – 1.17 0.76 139 904 exclusion phecode
355.1 Chronic pain syndrome Neurological 0.96 0.843 – 1.09 0.538 291 1467 exclusion phecode
356 Hereditary and idiopathic peripheral neuropathy Neurological 0.982 0.916 – 1.05 0.6 1010 4136 exclusion phecode
357 Inflammatory and toxic neuropathy Neurological 0.994 0.936 – 1.06 0.856 1360 5669 exclusion phecode
358 Myoneural disorders Neurological 1.02 0.915 – 1.13 0.735 387 2283 exclusion phecode
358.1 Myasthenia gravis Neurological 0.947 0.573 – 1.57 0.832 23 197 exclusion phecode
359 Muscular dystrophies and other myopathies Neurological 0.975 0.876 – 1.08 0.635 378 2177 exclusion phecode
359.1 Muscular dystrophies Neurological 0.569 0.32 – 1.01 0.0543 13 122 exclusion phecode
359.2 Myopathy Neurological 0.973 0.874 – 1.08 0.62 370 2102 exclusion phecode
360 Disorders of the globe Sense Organs 0.844 0.644 – 1.11 0.22 62 306 exclusion phecode
360.2 Progressive myopia Sense Organs 0.952 0.656 – 1.38 0.795 32 141 exclusion phecode
361 Retinal detachments and defects Sense Organs 0.834 0.734 – 0.947 0.00519 295 1588 exclusion phecode
361.1 Retinal detachment with retinal defect Sense Organs 0.838 0.69 – 1.02 0.0733 120 662 exclusion phecode
362 Other retinal disorders Sense Organs 0.959 0.904 – 1.02 0.168 1607 4119 exclusion phecode
362.2
Degeneration of macula and posterior pole of
Degeneration of macula and posterior pole of retina
 Sense Organs 0.982 0.911 – 1.06 0.645 941 2928 exclusion phecode
362.21 Macular degeneration, dry Sense Organs 0.895 0.76 – 1.05 0.183 193 676 exclusion phecode
362.22 Macular degeneration, wet Sense Organs 0.875 0.665 – 1.15 0.341 63 275 exclusion phecode
362.23 Cystoid macular degeneration of retina Sense Organs 1.03 0.876 – 1.22 0.687 180 807 exclusion phecode
362.26 Macular puckering of retina Sense Organs 1 0.907 – 1.11 0.934 453 1856 exclusion phecode
362.27 Drusen (degenerative) of retina Sense Organs 0.883 0.761 – 1.02 0.0985 217 972 exclusion phecode
362.29 Macular degeneration (senile) of retina NOS Sense Organs 0.969 0.894 – 1.05 0.441 814 2690 exclusion phecode
362.3 Other nondiabetic retinopathy Sense Organs 0.91 0.826 – 1 0.0538 508 1857 exclusion phecode
362.31 Separation of retinal layers Sense Organs 0.859 0.724 – 1.02 0.0832 157 925 exclusion phecode
362.4 Retinal vascular changes and abnomalities Sense Organs 0.905 0.804 – 1.02 0.1 320 1339 exclusion phecode
362.6 Peripheral retinal degenerations Sense Organs 0.98 0.832 – 1.15 0.807 170 843 exclusion phecode
362.7 Hereditary retinal dystrophies Sense Organs 1.04 0.823 – 1.32 0.728 88 453 exclusion phecode
362.8 Retinal hemorrhage/ischemia Sense Organs 0.89 0.723 – 1.1 0.272 103 640 exclusion phecode
362.9 Retinal edema Sense Organs 0.955 0.81 – 1.13 0.584 177 780 exclusion phecode
363
Chorioretinal inflammations, scars, and other
Chorioretinal inflammations, scars, and other disorders of choroid
 Sense Organs 0.863 0.738 – 1.01 0.0648 190 1001 exclusion phecode
363.3 Chorioretinal scars Sense Organs 0.827 0.691 – 0.989 0.0373 138 698 exclusion phecode
364 Corneal opacity and other disorders of cornea Sense Organs 0.939 0.844 – 1.04 0.243 419 2214 exclusion phecode
364.1 Corneal opacity Sense Organs 0.842 0.708 – 1 0.0531 151 858 exclusion phecode
364.2 Corneal edema Sense Organs 0.823 0.6 – 1.13 0.227 55 284 exclusion phecode
364.4 Corneal degenerations Sense Organs 0.836 0.699 – 0.999 0.049 148 903 exclusion phecode
364.41 Keratoconus Sense Organs 0.886 0.601 – 1.31 0.543 29 178 exclusion phecode
364.5 Corneal dystrophy Sense Organs 1.05 0.894 – 1.22 0.574 188 967 exclusion phecode
364.51 Fuchs' dystrophy Sense Organs 0.962 0.768 – 1.2 0.734 92 560 exclusion phecode
364.9 Cornea replaced by transplant Sense Organs 0.986 0.66 – 1.47 0.946 33 198 exclusion phecode
365 Glaucoma Sense Organs 0.935 0.872 – 1 0.0606 1000 4103 exclusion phecode
365.1 Open-angle glaucoma Sense Organs 0.926 0.819 – 1.05 0.221 313 1412 exclusion phecode
365.11 Primary open angle glaucoma Sense Organs 0.956 0.813 – 1.12 0.582 177 848 exclusion phecode
365.2 Primary angle-closure glaucoma Sense Organs 0.969 0.788 – 1.19 0.768 107 546 exclusion phecode
366 Cataract Sense Organs 1.03 0.977 – 1.08 0.293 3355 4691 exclusion phecode
366.1 Nonsenile Cataract Sense Organs 1.06 0.843 – 1.33 0.62 88 388 exclusion phecode
366.2 Senile cataract Sense Organs 1.02 0.965 – 1.08 0.502 2468 4156 exclusion phecode
367
Disorders of refraction and accommodation
Disorders of refraction and accommodation; blindness and low vision
 Sense Organs 0.968 0.928 – 1.01 0.136 3640 6032 exclusion phecode
367.1 Myopia Sense Organs 0.966 0.917 – 1.02 0.195 2059 5613 exclusion phecode
367.2 Astigmatism Sense Organs 0.978 0.925 – 1.03 0.423 1691 5352 exclusion phecode
367.8 Hypermetropia Sense Organs 0.94 0.868 – 1.02 0.122 784 3254 exclusion phecode
367.9 Blindness and low vision Sense Organs 0.954 0.863 – 1.05 0.357 495 2209 exclusion phecode
368 Visual disturbances Sense Organs 1.04 0.986 – 1.09 0.154 2006 7405 exclusion phecode
368.1 Amblyopia Sense Organs 1.15 0.99 – 1.34 0.0678 217 1410 exclusion phecode
368.2 Diplopia and disorders of binocular vision Sense Organs 1.01 0.908 – 1.13 0.797 386 2220 exclusion phecode
368.3 Anisometropia Sense Organs 0.926 0.741 – 1.16 0.498 87 471 exclusion phecode
368.4 Visual field defects Sense Organs 0.975 0.88 – 1.08 0.633 432 2219 exclusion phecode
368.9 Subjective visual disturbances Sense Organs 0.915 0.82 – 1.02 0.115 403 2198 exclusion phecode
368.91 Psychophysical visual disturbances Sense Organs 0.757 0.543 – 1.05 0.0999 51 228 exclusion phecode
369 Infection of the eye Sense Organs 0.946 0.888 – 1.01 0.0836 1240 4946 exclusion phecode
369.2 Eye infection, viral Sense Organs 1.04 0.879 – 1.22 0.669 178 990 exclusion phecode
369.5 Conjunctivitis, infectious Sense Organs 0.947 0.886 – 1.01 0.113 1082 4509 exclusion phecode
370 Keratitis Sense Organs 0.997 0.908 – 1.1 0.957 517 2507 exclusion phecode
370.1 Corneal ulcer Sense Organs 1.04 0.823 – 1.32 0.738 84 500 exclusion phecode
370.2 Superficial keratitis Sense Organs 0.916 0.789 – 1.06 0.251 213 1020 exclusion phecode
370.3 Keratoconjunctivitis Sense Organs 0.965 0.84 – 1.11 0.62 241 1169 exclusion phecode
370.31 Keratoconjunctivitis sicca Sense Organs 1.03 0.799 – 1.32 0.835 79 304 exclusion phecode
371 Inflammation of the eye Sense Organs 0.97 0.919 – 1.02 0.272 1779 5798 exclusion phecode
371.1 Uveitis, noninfectious or NOS Sense Organs 0.905 0.78 – 1.05 0.188 210 1129 exclusion phecode
371.2 Conjunctivitis, noninfectious Sense Organs 0.941 0.839 – 1.05 0.295 355 1858 exclusion phecode
371.21 Allergic conjunctivitis Sense Organs 0.927 0.819 – 1.05 0.234 302 1566 exclusion phecode
371.3 Inflammation of eyelids Sense Organs 0.967 0.911 – 1.03 0.283 1399 4897 exclusion phecode
371.33 Noninfectious dermatoses of eyelid Sense Organs 0.974 0.723 – 1.31 0.864 47 247 exclusion phecode
372 Disorders of conjunctiva Sense Organs 1.08 0.971 – 1.2 0.154 420 2128 exclusion phecode
374 Other disorders of eyelids Sense Organs 1.01 0.941 – 1.08 0.859 1102 4337 exclusion phecode
374.1 Ectropion or entropion Sense Organs 0.955 0.805 – 1.13 0.593 142 758 exclusion phecode
374.2 Lagophthalmos Sense Organs 0.944 0.696 – 1.28 0.712 46 369 exclusion phecode
374.3 Ptosis of eyelid Sense Organs 0.984 0.885 – 1.09 0.771 404 1973 exclusion phecode
374.6 Dermatochalasis Sense Organs 1 0.9 – 1.11 0.997 430 1859 exclusion phecode
375 Disorders of lacrimal system Sense Organs 0.935 0.88 – 0.993 0.0281 1517 4633 exclusion phecode
375.1 Dry eyes Sense Organs 0.948 0.894 – 1 0.069 1672 4750 exclusion phecode
375.2 Epiphora Sense Organs 0.914 0.77 – 1.09 0.304 167 816 exclusion phecode
376 Disorders of the orbit Sense Organs 0.962 0.752 – 1.23 0.757 77 591 exclusion phecode
377 Disorders of optic nerve and visual pathways Sense Organs 1.02 0.9 – 1.16 0.752 296 1648 exclusion phecode
377.1 Optic atrophy Sense Organs 0.895 0.739 – 1.08 0.259 123 616 exclusion phecode
377.3 Optic neuritis/neuropathy Sense Organs 1.08 0.915 – 1.26 0.377 174 1003 exclusion phecode
378
Strabismus and other disorders of binocular eye
Strabismus and other disorders of binocular eye movements
 Sense Organs 1.08 0.973 – 1.2 0.15 423 2264 exclusion phecode
378.1 Strabismus (not specified as paralytic) Sense Organs 1.03 0.912 – 1.17 0.601 289 1521 exclusion phecode
378.2 Nystagmus and other irregular eye movements Sense Organs 1.07 0.8 – 1.42 0.658 54 303 exclusion phecode
378.5 Paralytic strabismus Sense Organs 1.13 0.912 – 1.41 0.257 96 594 exclusion phecode
379 Other disorders of eye Sense Organs 0.975 0.925 – 1.03 0.348 2101 5291 exclusion phecode
379.1 Scleritis and episcleritis Sense Organs 1.04 0.779 – 1.38 0.807 66 348 exclusion phecode
379.2 Disorders of vitreous body Sense Organs 0.974 0.917 – 1.03 0.381 1562 4216 exclusion phecode
379.3 Aphakia and other disorders of lens Sense Organs 0.806 0.614 – 1.06 0.122 65 299 exclusion phecode
379.4 Anomalies of pupillary function Sense Organs 0.938 0.753 – 1.17 0.568 106 595 exclusion phecode
379.5 Disorders of iris and ciliary body Sense Organs 0.908 0.735 – 1.12 0.372 115 651 exclusion phecode
379.51 Pigmentary iris degeneration Sense Organs 0.853 0.498 – 1.46 0.562 22 111 exclusion phecode
379.9 Pain, swelling or discharge of eye Sense Organs 0.889 0.798 – 0.991 0.0344 404 1996 exclusion phecode
380 Disorders of external ear Sense Organs 1.01 0.943 – 1.09 0.751 981 4293 exclusion phecode
380.1 Otitis externa Sense Organs 0.985 0.9 – 1.08 0.748 578 3124 exclusion phecode
380.4 Impacted cerumen Sense Organs 1.04 0.972 – 1.11 0.266 1172 4895 exclusion phecode
381 Otitis media and Eustachian tube disorders Sense Organs 0.956 0.902 – 1.01 0.13 1408 6837 exclusion phecode
381.1 Otitis media Sense Organs 0.972 0.908 – 1.04 0.415 995 5630 exclusion phecode
381.11 Suppurative and unspecified otitis media Sense Organs 0.978 0.908 – 1.05 0.566 840 4876 exclusion phecode
381.2 Eustachian tube disorders Sense Organs 0.937 0.861 – 1.02 0.13 665 3656 exclusion phecode
381.3 Mastoiditis & related conditions Sense Organs 0.885 0.635 – 1.23 0.473 36 299 exclusion phecode
381.9 Otorrhea Sense Organs 0.943 0.752 – 1.18 0.611 92 686 exclusion phecode
382 Otalgia Sense Organs 0.998 0.917 – 1.09 0.966 668 3697 exclusion phecode
383 Otosclerosis Sense Organs 1.08 0.676 – 1.71 0.756 19 221 exclusion phecode
384 Other disorders of tympanic membrane Sense Organs 1.01 0.845 – 1.22 0.879 133 932 exclusion phecode
384.1 Myringitis Sense Organs 0.806 0.471 – 1.38 0.432 14 102 exclusion phecode
384.4 Perforation of tympanic membrane Sense Organs 1.06 0.855 – 1.3 0.612 99 727 exclusion phecode
385 Other disorders of middle ear and mastoid Sense Organs 1.16 0.932 – 1.45 0.181 87 749 exclusion phecode
385.3 Cholesteatoma Sense Organs 1.13 0.829 – 1.54 0.439 41 449 exclusion phecode
385.5
Tympanosclerosis and middle ear disease related
Tympanosclerosis and middle ear disease related to otitis media
 Sense Organs 0.771 0.507 – 1.17 0.223 25 208 exclusion phecode
386
Vertiginous syndromes and other disorders of
Vertiginous syndromes and other disorders of vestibular system
 Sense Organs 1.03 0.944 – 1.11 0.555 695 3334 exclusion phecode
386.1 Meniere's disease Sense Organs 1.2 0.964 – 1.5 0.102 93 608 exclusion phecode
386.2 Peripheral or central vertigo Sense Organs 1.05 0.963 – 1.15 0.261 603 2850 exclusion phecode
386.21 Central origin vertigo Sense Organs 1.07 0.965 – 1.19 0.201 453 2198 exclusion phecode
386.3 Labyrinthitis Sense Organs 1.06 0.961 – 1.16 0.259 540 2695 exclusion phecode
386.9
Dizziness and giddiness (Light-headedness and
Dizziness and giddiness (Light-headedness and vertigo)
 Sense Organs 1.04 0.988 – 1.08 0.143 2621 6767 exclusion phecode
388 Other disorders of ear Sense Organs 0.995 0.882 – 1.12 0.931 317 1867 exclusion phecode
389 Hearing loss Sense Organs 1.04 0.988 – 1.09 0.149 2596 6848 exclusion phecode
389.1 Sensorineural hearing loss Sense Organs 1 0.945 – 1.07 0.912 1458 5314 exclusion phecode
389.2 Conductive hearing loss Sense Organs 0.988 0.86 – 1.14 0.864 238 1661 exclusion phecode
389.3 Degenerative and vascular disorders of ear Sense Organs 0.793 0.617 – 1.02 0.072 87 385 exclusion phecode
389.4 Tinnitus Sense Organs 1.01 0.935 – 1.09 0.787 755 4233 exclusion phecode
389.5 Disorders of acoustic nerve Sense Organs 1.11 0.783 – 1.59 0.548 38 203 exclusion phecode
394 Rheumatic disease of the heart valves Circulatory System 1.04 0.958 – 1.12 0.362 818 2497 exclusion phecode
394.1 Mitral valve stenosis and aortic valve stenosis Circulatory System 1.09 0.933 – 1.27 0.277 223 686 exclusion phecode
394.2 Mitral valve disease Circulatory System 1.01 0.876 – 1.16 0.913 253 833 exclusion phecode
394.3 Aortic valve disease Circulatory System 1.07 0.867 – 1.31 0.54 118 313 exclusion phecode
394.4 Acute rheumatic heart disease Circulatory System 0.536 0.329 – 0.872 0.0121 28 84 exclusion phecode
394.7 Disease of tricuspid valve Circulatory System 1.02 0.901 – 1.16 0.725 342 992 exclusion phecode
395 Heart valve disorders Circulatory System 1.1 1.04 – 1.16 0.000887 1781 5007 exclusion phecode
395.1 Nonrheumatic mitral valve disorders Circulatory System 1.08 1 – 1.16 0.0373 944 3695 exclusion phecode
395.2 Nonrheumatic aortic valve disorders Circulatory System 1.13 1.05 – 1.21 0.000933 1106 3153 exclusion phecode
395.3 Nonrheumatic tricuspid valve disorders Circulatory System 1.09 0.953 – 1.25 0.205 271 916 exclusion phecode
395.4 Nonrheumatic pulmonary valve disorders Circulatory System 0.995 0.712 – 1.39 0.979 49 220 exclusion phecode
395.6 Heart valve replaced Circulatory System 1.06 0.97 – 1.16 0.195 632 1913 exclusion phecode
396 Abnormal heart sounds Circulatory System 1.07 1.01 – 1.13 0.0181 1701 6102 exclusion phecode
401 Hypertension Circulatory System 1.06 1.01 – 1.11 0.0309 6218 3441 exclusion phecode
401.1 Essential hypertension Circulatory System 1.06 1 – 1.11 0.0364 6184 3441 exclusion phecode
401.2 Hypertensive heart and/or renal disease Circulatory System 1.18 1.09 – 1.26 1.1e-05 1824 1963 exclusion phecode
401.21 Hypertensive heart disease Circulatory System 1.2 1.07 – 1.35 0.00145 503 865 exclusion phecode
401.22 Hypertensive chronic kidney disease Circulatory System 1.14 1.05 – 1.23 0.00112 1331 1724 exclusion phecode
401.3 Other hypertensive complications Circulatory System 1.14 1.06 – 1.23 0.000451 1319 2190 exclusion phecode
411 Ischemic Heart Disease Circulatory System 1.18 1.12 – 1.23 9.42e-11 3542 4571 exclusion phecode
411.1 Unstable angina (intermediate coronary syndrome) Circulatory System 1.18 1.07 – 1.3 0.00109 623 1458 exclusion phecode
411.2 Myocardial infarction Circulatory System 1.18 1.11 – 1.26 6.7e-07 1481 3181 exclusion phecode
411.3 Angina pectoris Circulatory System 1.17 1.1 – 1.26 3.27e-06 1377 2730 exclusion phecode
411.4 Coronary atherosclerosis Circulatory System 1.18 1.12 – 1.24 1.96e-10 3191 4127 exclusion phecode
411.41 Aneurysm and dissection of heart Circulatory System 1.37 1.05 – 1.78 0.0187 103 261 exclusion phecode
411.8
Other chronic ischemic heart disease
Other chronic ischemic heart disease, unspecified
 Circulatory System 1.2 1.14 – 1.27 2.76e-11 2730 3819 exclusion phecode
411.9
Other acute and subacute forms of ischemic
Other acute and subacute forms of ischemic heart disease
 Circulatory System 1.2 1.04 – 1.39 0.0127 270 766 exclusion phecode
414 Other forms of chronic heart disease Circulatory System 1.22 1.15 – 1.3 2.27e-10 1601 3367 exclusion phecode
414.2 ASCVD Circulatory System 1.14 1.02 – 1.29 0.0237 428 1190 exclusion phecode
415 Pulmonary heart disease Circulatory System 1.08 1.02 – 1.15 0.0137 1283 5664 exclusion phecode
415.1 Acute pulmonary heart disease Circulatory System 1.07 0.986 – 1.17 0.102 598 3595 exclusion phecode
415.11 Pulmonary embolism and infarction, acute Circulatory System 1.08 0.988 – 1.17 0.0934 594 3582 exclusion phecode
415.2 Chronic pulmonary heart disease Circulatory System 1.11 1.03 – 1.2 0.00521 884 3616 exclusion phecode
415.21 Primary pulmonary hypertension Circulatory System 1.07 0.951 – 1.21 0.256 370 1449 exclusion phecode
416 Cardiomegaly Circulatory System 0.959 0.879 – 1.05 0.353 635 2573 exclusion phecode
418 Nonspecific chest pain Circulatory System 1.05 1 – 1.09 0.0363 4841 4792 exclusion phecode
418.1 Precordial pain Circulatory System 1.07 0.981 – 1.17 0.129 699 2093 exclusion phecode
420 Carditis Circulatory System 1.03 0.954 – 1.12 0.417 742 3111 exclusion phecode
420.1 Myocarditis Circulatory System 0.991 0.731 – 1.34 0.954 49 193 exclusion phecode
420.2 Pericarditis Circulatory System 1.02 0.91 – 1.14 0.758 376 1611 exclusion phecode
420.21 Acute pericarditis Circulatory System 1.08 0.843 – 1.39 0.527 86 315 exclusion phecode
420.22 Chronic pericarditis Circulatory System 1.05 0.757 – 1.44 0.785 61 205 exclusion phecode
420.3 Endocarditis Circulatory System 1.01 0.908 – 1.13 0.806 388 1542 exclusion phecode
425 Cardiomyopathy Circulatory System 1.13 1.06 – 1.21 0.00047 1064 3986 exclusion phecode
425.1 Primary/intrinsic cardiomyopathies Circulatory System 1.11 1.04 – 1.19 0.00253 1032 3842 exclusion phecode
425.11 Hypertrophic obstructive cardiomyopathy Circulatory System 1.03 0.831 – 1.27 0.793 103 429 exclusion phecode
425.12 Other hypertrophic cardiomyopathy Circulatory System 1.27 0.993 – 1.63 0.0568 81 364 exclusion phecode
425.2 Secondary/extrinsic cardiomyopathies Circulatory System 1.04 0.882 – 1.23 0.638 166 675 exclusion phecode
425.8 Other cardiomyopathy Circulatory System 0.926 0.654 – 1.31 0.667 46 159 exclusion phecode
426 Cardiac conduction disorders Circulatory System 1.09 1.03 – 1.15 0.00136 4609 3177 exclusion phecode
426.2 Atrioventricular [AV] block Circulatory System 1.05 0.963 – 1.15 0.252 947 1279 exclusion phecode
426.21 First degree AV block Circulatory System 1.05 0.944 – 1.16 0.378 655 984 exclusion phecode
426.22 Mobitz II AV block Circulatory System 0.988 0.659 – 1.48 0.955 38 75 exclusion phecode
426.23 Second degree AV block Circulatory System 1.14 0.911 – 1.42 0.254 122 254 exclusion phecode
426.24 Atrioventricular block, complete Circulatory System 1.11 0.941 – 1.3 0.222 265 449 exclusion phecode
426.25 Other heart block Circulatory System 1.06 0.81 – 1.39 0.664 108 214 exclusion phecode
426.3 Bundle branch block Circulatory System 1.09 1 – 1.19 0.0397 1025 1573 exclusion phecode
426.31 Right bundle branch block Circulatory System 1.08 0.98 – 1.2 0.119 615 1207 exclusion phecode
426.32 Left bundle branch block Circulatory System 1.06 0.945 – 1.19 0.323 483 945 exclusion phecode
426.4 Anomalous atrioventricular excitation Circulatory System 0.828 0.465 – 1.47 0.521 20 80 exclusion phecode
426.7 Abnormal electrocardiogram [ECG] [EKG] Circulatory System 1.09 1.04 – 1.15 0.000996 4182 3155 exclusion phecode
426.8 Other cardiac conduction disorders Circulatory System 1.12 0.983 – 1.27 0.0879 334 857 exclusion phecode
426.9 Cardiac pacemaker/device in situ Circulatory System 1.12 1.02 – 1.23 0.0163 799 1301 exclusion phecode
426.91 Cardiac pacemaker in situ Circulatory System 1.09 0.974 – 1.22 0.134 527 914 exclusion phecode
426.92 Cardiac defibrillator in situ Circulatory System 1.16 1.03 – 1.31 0.0118 468 847 exclusion phecode
427 Cardiac dysrhythmias Circulatory System 1.09 1.04 – 1.14 0.000711 5493 3254 exclusion phecode
427.1 Paroxysmal tachycardia, unspecified Circulatory System 1.11 1.03 – 1.21 0.00938 1058 2099 exclusion phecode
427.11 Paroxysmal supraventricular tachycardia Circulatory System 1.1 1 – 1.22 0.0502 601 1627 exclusion phecode
427.12 Paroxysmal ventricular tachycardia Circulatory System 1.14 1.03 – 1.26 0.0147 624 1182 exclusion phecode
427.2 Atrial fibrillation and flutter Circulatory System 1.11 1.03 – 1.19 0.0041 2013 2138 exclusion phecode
427.21 Atrial fibrillation Circulatory System 1.1 1.03 – 1.19 0.00637 1972 2090 exclusion phecode
427.22 Atrial flutter Circulatory System 1.08 0.979 – 1.19 0.124 764 1206 exclusion phecode
427.3 Other specified cardiac dysrhythmias Circulatory System 1.11 1.05 – 1.17 0.000481 3224 3171 exclusion phecode
427.4 Cardiac arrest and ventricular fibrillation Circulatory System 1.09 0.944 – 1.27 0.231 270 627 exclusion phecode
427.41 Ventricular fibrillation and flutter Circulatory System 1.25 0.979 – 1.6 0.0739 125 292 exclusion phecode
427.42 Cardiac arrest Circulatory System 1.1 0.933 – 1.29 0.26 204 501 exclusion phecode
427.5 Arrhythmia (cardiac) NOS Circulatory System 1.07 1.01 – 1.14 0.0232 2442 3146 exclusion phecode
427.6 Premature beats Circulatory System 1.09 1 – 1.18 0.0413 1033 1948 exclusion phecode
427.61 Supraventricular premature beats Circulatory System 1.08 0.937 – 1.24 0.294 309 774 exclusion phecode
427.7 Tachycardia NOS Circulatory System 1.11 1.05 – 1.18 0.000747 1836 3185 exclusion phecode
427.8 Sinoatrial node dysfunction (Bradycardia) Circulatory System 1.06 0.942 – 1.2 0.319 440 822 exclusion phecode
427.9 Palpitations Circulatory System 1.08 1.01 – 1.15 0.0184 1748 3146 exclusion phecode
428 Congestive heart failure; nonhypertensive Circulatory System 1.15 1.08 – 1.22 5.94e-06 2080 3117 exclusion phecode
428.1 Congestive heart failure (CHF) NOS Circulatory System 1.16 1.09 – 1.23 4.12e-06 1808 2929 exclusion phecode
428.2 Heart failure NOS Circulatory System 1.13 1.06 – 1.21 8.95e-05 1810 2822 exclusion phecode
428.3
Heart failure with reduced EF [Systolic or
Heart failure with reduced EF [Systolic or combined heart failure]
 Circulatory System 1.2 1.11 – 1.3 4.25e-06 1027 1937 exclusion phecode
428.4
Heart failure with preserved EF [Diastolic
Heart failure with preserved EF [Diastolic heart failure]
 Circulatory System 1.07 0.985 – 1.16 0.113 932 1778 exclusion phecode
429
Ill-defined descriptions and complications of
Ill-defined descriptions and complications of heart disease
 Circulatory System 1.11 1.06 – 1.16 3.35e-06 4681 4529 exclusion phecode
429.1 Heart transplant/surgery Circulatory System 1.11 1.01 – 1.22 0.0233 669 1550 exclusion phecode
429.2 Abnormal function study of cardiovascular system Circulatory System 1.11 1.06 – 1.17 7.19e-05 2766 4064 exclusion phecode
429.3 Symptoms involving cardiovascular system Circulatory System 1.11 1.06 – 1.16 1.26e-05 3645 4527 exclusion phecode
429.9 Cardiac complications, not elsewhere classified Circulatory System 1.17 1.03 – 1.32 0.014 348 884 exclusion phecode
430 Intracranial hemorrhage Circulatory System 1.06 0.927 – 1.21 0.402 262 1573 exclusion phecode
430.1 Subarachnoid hemorrhage Circulatory System 1.06 0.834 – 1.34 0.653 89 477 exclusion phecode
430.2 Intracerebral hemorrhage Circulatory System 1.09 0.891 – 1.32 0.418 116 661 exclusion phecode
430.3 Subdural hemorrhage Circulatory System 1.1 0.89 – 1.35 0.391 102 568 exclusion phecode
433 Cerebrovascular disease Circulatory System 1.09 1.03 – 1.15 0.00206 1974 5967 exclusion phecode
433.1 Occlusion and stenosis of precerebral arteries Circulatory System 1.08 1 – 1.17 0.0422 907 3195 exclusion phecode
433.11
Occlusion of cerebral arteries, with cerebral
Occlusion of cerebral arteries, with cerebral infarction
 Circulatory System 1.18 0.987 – 1.42 0.0696 132 551 exclusion phecode
433.12 Cerebral atherosclerosis Circulatory System 1.42 0.959 – 2.09 0.0804 49 181 exclusion phecode
433.2 Occlusion of cerebral arteries Circulatory System 1.1 1.02 – 1.18 0.00936 895 4145 exclusion phecode
433.21
Cerebral artery occlusion, with cerebral
Cerebral artery occlusion, with cerebral infarction
 Circulatory System 1.1 1.02 – 1.18 0.0139 868 4020 exclusion phecode
433.3 Cerebral ischemia Circulatory System 1.08 1.01 – 1.16 0.0253 1077 4352 exclusion phecode
433.31 Transient cerebral ischemia Circulatory System 1.07 0.997 – 1.15 0.0593 944 3957 exclusion phecode
433.5 Cerebral aneurysm Circulatory System 1.04 0.845 – 1.27 0.738 110 788 exclusion phecode
433.6 Acute, but ill-defined cerebrovascular disease Circulatory System 1.07 0.934 – 1.22 0.336 283 1004 exclusion phecode
433.8 Late effects of cerebrovascular disease Circulatory System 1.08 0.954 – 1.22 0.226 321 1355 exclusion phecode
440 Atherosclerosis Circulatory System 1.08 1.01 – 1.16 0.0172 1322 3265 exclusion phecode
440.1 Atherosclerosis of renal artery Circulatory System 1.07 0.862 – 1.33 0.534 118 343 exclusion phecode
440.2 Atherosclerosis of the extremities Circulatory System 1.06 0.984 – 1.15 0.12 866 2432 exclusion phecode
440.21
Atherosclerosis of native arteries of the
Atherosclerosis of native arteries of the extremities with ulceration or gangrene
 Circulatory System 1.1 0.927 – 1.3 0.284 184 651 exclusion phecode
440.22
Atherosclerosis of native arteries of the
Atherosclerosis of native arteries of the extremities with intermittent claudication
 Circulatory System 1.06 0.968 – 1.17 0.203 627 1828 exclusion phecode
440.9 Atherosclerosis of aorta Circulatory System 1.17 1.05 – 1.3 0.0049 475 1362 exclusion phecode
441 Vascular insufficiency of intestine Circulatory System 0.95 0.816 – 1.11 0.504 231 883 exclusion phecode
441.1 Acute vascular insufficiency of intestine Circulatory System 0.853 0.688 – 1.06 0.146 112 418 exclusion phecode
441.2 Chronic vascular insufficiency of intestine Circulatory System 1.05 0.792 – 1.38 0.752 64 277 exclusion phecode
442 Other aneurysm Circulatory System 1.04 0.972 – 1.11 0.251 1158 3401 exclusion phecode
442.1 Aortic aneurysm Circulatory System 1.04 0.969 – 1.13 0.258 940 2672 exclusion phecode
442.11 Abdominal aortic aneurysm Circulatory System 1.07 0.972 – 1.18 0.163 509 1708 exclusion phecode
442.2 Aneurysm of iliac artery Circulatory System 1.1 0.871 – 1.39 0.426 90 304 exclusion phecode
442.3 Aneurysm of artery of lower extremity Circulatory System 1.12 0.871 – 1.45 0.367 83 266 exclusion phecode
442.4 Arterial dissection Circulatory System 0.876 0.695 – 1.11 0.265 85 271 exclusion phecode
442.8 Aneurysm of other specified artery Circulatory System 1.11 0.923 – 1.33 0.272 148 621 exclusion phecode
443 Peripheral vascular disease Circulatory System 1.12 1.05 – 1.19 0.000586 1382 4093 exclusion phecode
443.1 Raynaud's syndrome Circulatory System 1.09 0.952 – 1.26 0.204 240 1213 exclusion phecode
443.7
Peripheral angiopathy in diseases classified
Peripheral angiopathy in diseases classified elsewhere
 Circulatory System 1.05 0.88 – 1.25 0.604 170 626 exclusion phecode
443.8 Other specified peripheral vascular diseases Circulatory System 1.12 1.05 – 1.2 0.00119 1118 3679 exclusion phecode
443.9 Peripheral vascular disease, unspecified Circulatory System 1.12 1.05 – 1.2 0.00126 1136 3199 exclusion phecode
444 Arterial embolism and thrombosis Circulatory System 1.08 0.966 – 1.22 0.167 390 1423 exclusion phecode
444.1
Arterial embolism and thrombosis of lower
Arterial embolism and thrombosis of lower extremity artery
 Circulatory System 1.1 0.917 – 1.31 0.315 162 568 exclusion phecode
444.2 Embolism and thrombosis of abdominal aorta Circulatory System 1.08 0.82 – 1.42 0.593 76 244 exclusion phecode
446 Polyarteritis nodosa and allied conditions Circulatory System 1.08 0.917 – 1.26 0.37 185 819 exclusion phecode
446.4 Wegener's granulomatosis Circulatory System 1.36 0.96 – 1.93 0.0835 39 193 exclusion phecode
446.5 Giant cell arteritis Circulatory System 1.05 0.71 – 1.54 0.819 33 117 exclusion phecode
446.9 Arteritis NOS Circulatory System 1.03 0.838 – 1.26 0.799 119 542 exclusion phecode
447 Other disorders of arteries and arterioles Circulatory System 1.04 0.974 – 1.11 0.237 1220 3675 exclusion phecode
447.1 Stricture of artery Circulatory System 1.11 0.958 – 1.28 0.169 255 828 exclusion phecode
447.7 Aortic ectasia Circulatory System 0.951 0.854 – 1.06 0.366 432 1374 exclusion phecode
448 Disease of capillaries Circulatory System 0.929 0.836 – 1.03 0.173 423 2114 exclusion phecode
450 Noninfectious disorders of lymphatic channels Circulatory System 0.986 0.901 – 1.08 0.755 544 4198 exclusion phecode
451 Phlebitis and thrombophlebitis Circulatory System 1.01 0.885 – 1.15 0.876 271 1178 exclusion phecode
451.2
Phlebitis and thrombophlebitis of lower
Phlebitis and thrombophlebitis of lower extremities
 Circulatory System 0.995 0.794 – 1.25 0.964 88 407 exclusion phecode
452 Other venous embolism and thrombosis Circulatory System 1.02 0.963 – 1.09 0.453 1474 4441 exclusion phecode
452.1 Iatrogenic pulmonary embolism and infarction Circulatory System 1.01 0.795 – 1.28 0.953 100 433 exclusion phecode
452.2 Deep vein thrombosis [DVT] Circulatory System 1.04 0.966 – 1.12 0.302 937 3985 exclusion phecode
452.8 Postphlebitic syndrome Circulatory System 0.918 0.65 – 1.3 0.629 32 224 exclusion phecode
453 Chronic venous hypertension Circulatory System 0.986 0.79 – 1.23 0.898 97 374 exclusion phecode
454 Varicose veins Circulatory System 0.946 0.88 – 1.02 0.128 973 3757 exclusion phecode
454.1 Varicose veins of lower extremity Circulatory System 0.951 0.881 – 1.03 0.191 876 3296 exclusion phecode
454.11 Varicose veins of lower extremity, symptomtic Circulatory System 0.936 0.855 – 1.02 0.152 615 2370 exclusion phecode
455 Hemorrhoids Circulatory System 1.07 1.01 – 1.13 0.0162 2201 4612 exclusion phecode
456 Chronic venous insufficiency [CVI] Circulatory System 0.951 0.891 – 1.01 0.129 1277 3892 exclusion phecode
457
Encounter for long-term (current) use of
Encounter for long-term (current) use of anticoagulants, antithrombotics, aspirin
 Circulatory System 1.13 1.04 – 1.23 0.00279 852 2324 exclusion phecode
457.2
Encounter for long-term (current) use of
Encounter for long-term (current) use of antiplatelets/antithrombotics
 Circulatory System 1.14 0.945 – 1.37 0.173 150 506 exclusion phecode
457.3 Encounter for long-term (current) use of aspirin Circulatory System 1.13 1.04 – 1.23 0.00433 802 2236 exclusion phecode
458 Hypotension Circulatory System 1.11 1.05 – 1.17 0.000244 2116 5153 exclusion phecode
458.1 Orthostatic hypotension Circulatory System 1.05 0.963 – 1.16 0.252 625 2289 exclusion phecode
458.2 Iatrogenic hypotension Circulatory System 1.07 0.962 – 1.18 0.225 494 1817 exclusion phecode
458.9 Hypotension NOS Circulatory System 1.1 1.04 – 1.16 0.000571 1940 4994 exclusion phecode
459 Other disorders of circulatory system Circulatory System 1.08 1.03 – 1.13 0.00196 2737 5607 exclusion phecode
459.1 Hemorrhage NOS Circulatory System 1.01 0.897 – 1.14 0.838 347 1451 exclusion phecode
459.7 Blood vessel replaced Circulatory System 1.14 1.03 – 1.26 0.013 509 1952 exclusion phecode
459.9 Circulatory disease NEC Circulatory System 1.09 1.03 – 1.15 0.00128 2368 5371 exclusion phecode
464 Acute sinusitis Respiratory 0.946 0.897 – 0.999 0.0448 1924 4830 exclusion phecode
465
Acute upper respiratory infections of multiple
Acute upper respiratory infections of multiple or unspecified sites
 Respiratory 0.939 0.899 – 0.98 0.00374 3814 5406 exclusion phecode
465.2 Acute pharyngitis Respiratory 0.934 0.885 – 0.986 0.0129 2053 4764 exclusion phecode
465.4 Acute laryngitis and tracheitis Respiratory 0.906 0.754 – 1.09 0.296 147 702 exclusion phecode
470 Septal Deviations/Turbinate Hypertrophy Respiratory 0.964 0.874 – 1.06 0.459 484 2635 exclusion phecode
471 Nasal polyps Respiratory 0.973 0.825 – 1.15 0.742 151 981 exclusion phecode
472 Chronic pharyngitis and nasopharyngitis Respiratory 0.917 0.843 – 0.998 0.0455 689 2867 exclusion phecode
473 Diseases of the larynx and vocal cords Respiratory 0.931 0.862 – 1.01 0.0694 805 3933 exclusion phecode
473.1 Chronic laryngitis Respiratory 0.769 0.512 – 1.16 0.206 27 120 exclusion phecode
473.3 Paralysis/spasm of vocal cords or larynx Respiratory 1.07 0.897 – 1.27 0.468 157 952 exclusion phecode
473.4 Voice disturbance Respiratory 0.963 0.884 – 1.05 0.396 627 3351 exclusion phecode
474 Acute and chronic tonsillitis Respiratory 0.891 0.778 – 1.02 0.0923 283 1201 exclusion phecode
474.1 Acute tonsillitis Respiratory 0.95 0.762 – 1.19 0.65 104 451 exclusion phecode
474.2 Chronic tonsillitis and adenoiditis Respiratory 0.851 0.729 – 0.994 0.0422 214 939 exclusion phecode
475 Chronic sinusitis Respiratory 0.938 0.883 – 0.996 0.0367 1476 4360 exclusion phecode
475.9 Postnasal drip Respiratory 0.923 0.822 – 1.04 0.178 379 1632 exclusion phecode
476 Allergic rhinitis Respiratory 0.921 0.88 – 0.963 0.000316 3676 4423 exclusion phecode
477 Epistaxis or throat hemorrhage Respiratory 1.1 0.992 – 1.21 0.0712 490 1877 exclusion phecode
478 Throat pain Respiratory 0.999 0.819 – 1.22 0.992 127 646 exclusion phecode
479 Other upper respiratory disease Respiratory 0.958 0.906 – 1.01 0.125 1850 4404 exclusion phecode
480 Pneumonia Respiratory 1.05 1 – 1.11 0.0499 2144 6201 exclusion phecode
480.1 Bacterial pneumonia Respiratory 1.15 1.04 – 1.27 0.00494 515 2103 exclusion phecode
480.11 Pneumococcal pneumonia Respiratory 1.19 1.03 – 1.37 0.0172 254 1037 exclusion phecode
480.12 Pseudomonal pneumonia Respiratory 1.11 0.845 – 1.45 0.462 76 254 exclusion phecode
480.13 MRSA pneumonia Respiratory 1.07 0.784 – 1.46 0.67 53 240 exclusion phecode
480.2 Viral pneumonia Respiratory 1.04 0.847 – 1.28 0.697 110 448 exclusion phecode
480.3 Pneumonia due to fungus (mycoses) Respiratory 1.24 0.953 – 1.62 0.108 71 309 exclusion phecode
480.5 Bronchopneumonia and lung abscess Respiratory 0.955 0.712 – 1.28 0.757 55 239 exclusion phecode
481 Influenza Respiratory 1.03 0.943 – 1.13 0.489 591 2674 exclusion phecode
483 Acute bronchitis and bronchiolitis Respiratory 0.993 0.937 – 1.05 0.826 1461 5219 exclusion phecode
495 Asthma Respiratory 0.984 0.937 – 1.03 0.528 2235 6145 exclusion phecode
495.1 Chronic obstructive asthma Respiratory 0.999 0.839 – 1.19 0.993 153 787 exclusion phecode
495.11 Chronic obstructive asthma with exacerbation Respiratory 1.28 0.907 – 1.82 0.158 48 206 exclusion phecode
495.2 Asthma with exacerbation Respiratory 1.01 0.925 – 1.11 0.786 573 3051 exclusion phecode
496 Chronic airway obstruction Respiratory 1.05 0.986 – 1.11 0.138 1459 5192 exclusion phecode
496.1 Emphysema Respiratory 1.04 0.952 – 1.13 0.409 612 3619 exclusion phecode
496.2 Chronic bronchitis Respiratory 1.05 0.987 – 1.12 0.12 1144 4873 exclusion phecode
496.21 Obstructive chronic bronchitis Respiratory 1.06 0.993 – 1.14 0.0816 1045 4667 exclusion phecode
496.3 Bronchiectasis Respiratory 1.16 1 – 1.35 0.0471 208 1154 exclusion phecode
497 Bronchitis Respiratory 1.01 0.937 – 1.09 0.765 792 3795 exclusion phecode
498 Acute bronchospasm Respiratory 0.953 0.819 – 1.11 0.528 220 953 exclusion phecode
499 Cystic fibrosis Respiratory 1.11 0.856 – 1.44 0.427 67 376 exclusion phecode
500 Lung disease due to external agents Respiratory 0.907 0.78 – 1.06 0.207 197 955 exclusion phecode
500.1 Extrinsic allergic alveolitis Respiratory 0.724 0.501 – 1.05 0.0857 35 150 exclusion phecode
500.2 Pneumoconiosis Respiratory 1.04 0.725 – 1.48 0.845 35 153 exclusion phecode
501 Pneumonitis due to inhalation of food or vomitus Respiratory 1.09 0.942 – 1.26 0.251 235 1136 exclusion phecode
502 Postinflammatory pulmonary fibrosis Respiratory 0.98 0.865 – 1.11 0.757 308 1442 exclusion phecode
503 Pulmonary congestion and hypostasis Respiratory 1.11 1 – 1.24 0.0479 448 1624 exclusion phecode
504 Other alveolar and parietoalveolar pneumonopathy Respiratory 1.02 0.885 – 1.18 0.762 228 1095 exclusion phecode
504.1 Idiopathic fibrosing alveolitis Respiratory 1.08 0.887 – 1.32 0.442 122 579 exclusion phecode
505 Other pulmonary inflamation or edema Respiratory 1.09 1 – 1.17 0.038 834 2901 exclusion phecode
506 Empyema and pneumothorax Respiratory 1.11 1.04 – 1.19 0.00276 1066 4202 exclusion phecode
507 Pleurisy; pleural effusion Respiratory 1.08 1.01 – 1.15 0.0306 1152 4433 exclusion phecode
508
Pulmonary collapse; interstitial and
Pulmonary collapse; interstitial and compensatory emphysema
 Respiratory 1.1 1.02 – 1.19 0.00932 870 3907 exclusion phecode
509 Respiratory failure, insufficiency, arrest Respiratory 1.15 1.09 – 1.22 1.31e-06 1677 4953 exclusion phecode
509.1 Respiratory failure Respiratory 1.13 1.04 – 1.22 0.0032 802 3328 exclusion phecode
509.2 Respiratory insufficiency Respiratory 1.1 0.997 – 1.22 0.0561 513 2058 exclusion phecode
509.3
Pulmonary insufficiency or respiratory failure
Pulmonary insufficiency or respiratory failure following trauma and surgery
 Respiratory 1.11 1.02 – 1.2 0.016 789 2829 exclusion phecode
509.8
Dependence on respirator [Ventilator] or
Dependence on respirator [Ventilator] or supplemental oxygen
 Respiratory 1.13 1.04 – 1.22 0.00431 717 2991 exclusion phecode
510 Other diseases of lung Respiratory 1.01 0.964 – 1.07 0.588 2036 6644 exclusion phecode
510.2 Lung transplant Respiratory 1.12 0.885 – 1.41 0.352 104 352 exclusion phecode
512 Other symptoms of respiratory system Respiratory 1.01 0.963 – 1.05 0.782 6300 3373 exclusion phecode
512.1 Wheezing Respiratory 0.959 0.871 – 1.06 0.393 613 1758 exclusion phecode
512.2 Painful respiration Respiratory 1 0.93 – 1.09 0.905 942 2631 exclusion phecode
512.3 Abnormal chest sounds Respiratory 0.95 0.783 – 1.15 0.607 153 363 exclusion phecode
512.7 Shortness of breath Respiratory 1.06 1 – 1.11 0.0329 3896 3353 exclusion phecode
512.8 Cough Respiratory 0.975 0.929 – 1.02 0.308 3808 3372 exclusion phecode
512.9 Other dyspnea Respiratory 1.03 0.981 – 1.08 0.231 3994 3364 exclusion phecode
513 Respiratory abnormalities Respiratory 1.05 1 – 1.09 0.0382 4577 5094 exclusion phecode
513.3 Hypoventilation Respiratory 0.981 0.876 – 1.1 0.743 398 1491 exclusion phecode
513.31 Apnea Respiratory 1.07 0.914 – 1.26 0.384 189 786 exclusion phecode
513.32 Orthopnea Respiratory 0.972 0.789 – 1.2 0.793 123 364 exclusion phecode
513.4 Hyperventilation Respiratory 1.16 1 – 1.35 0.0475 239 743 exclusion phecode
513.8 Disorders of diaphragm Respiratory 1.15 0.916 – 1.45 0.226 95 411 exclusion phecode
514 Abnormal findings examination of lungs Respiratory 1.01 0.951 – 1.06 0.852 1588 6667 exclusion phecode
514.1
Abnormal results of function study of pulmonary
Abnormal results of function study of pulmonary system
 Respiratory 1.08 0.888 – 1.32 0.43 120 582 exclusion phecode
514.2 Solitary pulmonary nodule Respiratory 0.995 0.926 – 1.07 0.897 865 5271 exclusion phecode
516 Abnormal sputum Respiratory 1.15 1.01 – 1.31 0.0324 281 1611 exclusion phecode
516.1 Hemoptysis Respiratory 1.24 1.08 – 1.43 0.00251 232 1327 exclusion phecode
519
Other diseases of respiratory system, not
Other diseases of respiratory system, not elsewhere classified
 Respiratory 1.03 0.978 – 1.08 0.292 2249 7145 exclusion phecode
519.1 Tracheostomy complications Respiratory 1.18 0.882 – 1.57 0.269 48 355 exclusion phecode
519.2 Respiratory complications Respiratory 1.06 0.897 – 1.24 0.51 169 773 exclusion phecode
519.8 Other diseases of respiratory system, NEC Respiratory 0.961 0.874 – 1.06 0.403 512 3067 exclusion phecode
519.9
Symptoms involving respiratory system and other
Symptoms involving respiratory system and other chest symptoms
 Respiratory 1.05 0.992 – 1.11 0.0965 1721 6322 exclusion phecode
520 Disorders of tooth development Digestive 0.904 0.693 – 1.18 0.456 56 672 exclusion phecode
520.1 Hereditary disturbances in tooth structure Digestive 0.866 0.6 – 1.25 0.442 29 331 exclusion phecode
520.2 Disturbances in tooth eruption Digestive 0.947 0.625 – 1.43 0.796 24 356 exclusion phecode
521 Diseases of hard tissues of teeth Digestive 1.03 0.896 – 1.19 0.671 223 1741 exclusion phecode
521.1 Dental caries Digestive 1.03 0.887 – 1.19 0.724 202 1618 exclusion phecode
521.2 Dental abrasion, erosion and attrition Digestive 1.27 0.726 – 2.23 0.399 17 83 exclusion phecode
522 Diseases of pulp and periapical tissues Digestive 1.05 0.898 – 1.24 0.516 179 1104 exclusion phecode
522.5 Periapical abscess Digestive 1.02 0.863 – 1.21 0.812 166 935 exclusion phecode
523 Gingival and periodontal diseases Digestive 0.952 0.823 – 1.1 0.506 207 1410 exclusion phecode
523.1 Gingivitis Digestive 0.771 0.566 – 1.05 0.0999 49 272 exclusion phecode
523.3 Periodontitis (acute or chronic) Digestive 0.934 0.767 – 1.14 0.499 109 710 exclusion phecode
523.31 Acute periodontitis Digestive 0.926 0.739 – 1.16 0.507 88 595 exclusion phecode
523.32 Chronic periodontitis Digestive 0.896 0.622 – 1.29 0.557 32 233 exclusion phecode
524 Dentofacial anomalies, including malocclusion Digestive 0.689 0.486 – 0.978 0.037 40 566 exclusion phecode
524.3 Anomalies of tooth position/malocclusion Digestive 0.661 0.42 – 1.04 0.0737 21 325 exclusion phecode
525
Other diseases of the teeth and supporting
Other diseases of the teeth and supporting structures
 Digestive 1.01 0.889 – 1.15 0.848 265 1970 exclusion phecode
525.1 Loss of teeth or edentulism Digestive 1.06 0.826 – 1.36 0.654 72 683 exclusion phecode
526 Diseases of the jaws Digestive 0.958 0.881 – 1.04 0.322 627 4938 exclusion phecode
526.1 Cysts of the jaws Digestive 0.937 0.647 – 1.36 0.73 33 418 exclusion phecode
526.3 Anomalies of jaw size/symmetry Digestive 0.783 0.529 – 1.16 0.223 27 341 exclusion phecode
526.4 Temporomandibular joint disorders Digestive 0.999 0.896 – 1.11 0.991 385 2778 exclusion phecode
526.41 Temporomandibular joint disorder, unspecified Digestive 0.951 0.839 – 1.08 0.425 291 2172 exclusion phecode
526.42 Arthralgia/ankylosis of temporomandibular joint Digestive 0.967 0.818 – 1.14 0.699 157 1339 exclusion phecode
526.5 Inflammatory conditions of jaw Digestive 0.869 0.635 – 1.19 0.381 39 539 exclusion phecode
526.8 Exostosis of jaw Digestive 0.664 0.346 – 1.27 0.217 10 102 exclusion phecode
526.9 Jaw disease NOS Digestive 0.833 0.666 – 1.04 0.112 82 944 exclusion phecode
527 Diseases of the salivary glands Digestive 1.03 0.935 – 1.13 0.551 472 3605 exclusion phecode
527.1 Hypertrophy of salivary gland Digestive 1 0.621 – 1.62 0.988 17 128 exclusion phecode
527.2 Sialoadenitis Digestive 0.935 0.769 – 1.14 0.5 114 782 exclusion phecode
527.7 Disturbance of salivary secretion Digestive 1.06 0.927 – 1.2 0.41 268 1945 exclusion phecode
527.8 Other specified diseases of the salivary glands Digestive 1.19 0.91 – 1.55 0.206 59 494 exclusion phecode
528
Diseases of the oral soft tissues, excluding
Diseases of the oral soft tissues, excluding lesions specific for gingiva and tongue
 Digestive 0.956 0.883 – 1.03 0.264 698 5234 exclusion phecode
528.1 Stomatitis and mucositis Digestive 0.877 0.759 – 1.01 0.0731 215 1333 exclusion phecode
528.11 Stomatitis and mucositis (ulcerative) Digestive 0.813 0.63 – 1.05 0.11 67 401 exclusion phecode
528.12 Oral aphthae Digestive 0.84 0.666 – 1.06 0.138 89 479 exclusion phecode
528.3 Cellulitis and abscess of oral soft tissues Digestive 0.931 0.701 – 1.24 0.621 47 425 exclusion phecode
528.4 Cysts of oral soft tissues Digestive 1.24 0.816 – 1.9 0.31 22 225 exclusion phecode
528.41 Cyst of the salivary gland Digestive 1.05 0.645 – 1.7 0.851 16 139 exclusion phecode
528.5 Diseases of lips Digestive 0.933 0.778 – 1.12 0.452 148 966 exclusion phecode
528.6 Leukoplakia of oral mucosa Digestive 1.02 0.699 – 1.48 0.936 24 277 exclusion phecode
528.7 Sialolithiasis Digestive 1.49 1.08 – 2.06 0.0145 47 301 exclusion phecode
529 Diseases and other conditions of the tongue Digestive 1.09 0.937 – 1.28 0.259 182 1436 exclusion phecode
529.1 Glossitis Digestive 1.12 0.814 – 1.53 0.494 42 245 exclusion phecode
529.6 Glossodynia Digestive 1.07 0.772 – 1.49 0.682 43 360 exclusion phecode
530 Diseases of esophagus Digestive 0.989 0.948 – 1.03 0.617 4685 4629 exclusion phecode
530.1 Esophagitis, GERD and related diseases Digestive 0.992 0.95 – 1.03 0.698 4584 4629 exclusion phecode
530.11 GERD Digestive 0.989 0.948 – 1.03 0.623 4466 4628 exclusion phecode
530.12 Ulcer of esophagus Digestive 0.958 0.801 – 1.15 0.637 155 702 exclusion phecode
530.13 Barrett's esophagus Digestive 0.946 0.82 – 1.09 0.449 214 1320 exclusion phecode
530.14 Reflux esophagitis Digestive 0.938 0.866 – 1.02 0.122 747 3050 exclusion phecode
530.15 Eosinophilic esophagitis Digestive 0.786 0.59 – 1.05 0.0985 66 369 exclusion phecode
530.2 Esophageal bleeding (varices/hemorrhage) Digestive 0.973 0.847 – 1.12 0.703 247 1130 exclusion phecode
530.3 Stricture and stenosis of esophagus Digestive 0.932 0.817 – 1.06 0.297 257 1468 exclusion phecode
530.5 Disorders of esophageal motility Digestive 1.1 0.927 – 1.31 0.273 161 916 exclusion phecode
530.6 Diverticulum of esophagus, acquired Digestive 1.42 0.823 – 2.45 0.208 16 208 exclusion phecode
530.7 Gastroesophageal laceration-hemorrhage syndrome Digestive 0.694 0.486 – 0.99 0.0442 39 157 exclusion phecode
530.9 Heartburn Digestive 0.901 0.82 – 0.991 0.0321 520 2574 exclusion phecode
531 Peptic ulcer (excl. esophageal) Digestive 0.991 0.916 – 1.07 0.811 756 4293 exclusion phecode
531.1 Hemorrhage from gastrointestinal ulcer Digestive 0.982 0.839 – 1.15 0.825 172 806 exclusion phecode
531.2 Gastric ulcer Digestive 0.995 0.896 – 1.1 0.92 439 2531 exclusion phecode
531.3 Duodenal ulcer Digestive 0.991 0.849 – 1.16 0.911 191 978 exclusion phecode
531.4 Peptic ulcer, site unspecified Digestive 0.885 0.782 – 1 0.052 316 1750 exclusion phecode
531.5 Gastrojejunal ulcer Digestive 1.15 0.871 – 1.53 0.32 59 279 exclusion phecode
532 Dysphagia Digestive 0.97 0.915 – 1.03 0.315 1608 4368 exclusion phecode
535 Gastritis and duodenitis Digestive 1.01 0.94 – 1.08 0.866 1061 5159 exclusion phecode
535.1 Acute gastritis Digestive 1.02 0.914 – 1.13 0.756 420 2326 exclusion phecode
535.2 Atrophic gastritis Digestive 0.923 0.756 – 1.13 0.43 118 616 exclusion phecode
535.6 Duodenitis Digestive 1.03 0.861 – 1.24 0.717 138 663 exclusion phecode
535.8 Other specified gastritis Digestive 0.939 0.819 – 1.08 0.363 261 1292 exclusion phecode
535.9 Gastritis and duodenitis, NOS Digestive 0.977 0.887 – 1.08 0.639 500 2461 exclusion phecode
536 Disorders of function of stomach Digestive 1.02 0.951 – 1.09 0.642 1084 5166 exclusion phecode
536.3 Gastroparesis Digestive 1.12 0.993 – 1.27 0.064 303 1647 exclusion phecode
536.7
Complications of gastrostomy, colostomy and
Complications of gastrostomy, colostomy and enterostomy
 Digestive 1.13 0.923 – 1.38 0.237 108 637 exclusion phecode
536.8
Dyspepsia and other specified disorders of
Dyspepsia and other specified disorders of function of stomach
 Digestive 0.978 0.906 – 1.06 0.569 823 4075 exclusion phecode
537 Other disorders of stomach and duodenum Digestive 1.06 0.994 – 1.12 0.0781 1292 5626 exclusion phecode
537.1 Lesions of stomach and duodenum Digestive 0.936 0.745 – 1.18 0.569 94 379 exclusion phecode
539 Bariatric surgery Digestive 0.928 0.847 – 1.02 0.11 574 2926 exclusion phecode
540 Appendiceal conditions Digestive 0.994 0.844 – 1.17 0.939 176 1004 exclusion phecode
540.1 Appendicitis Digestive 1.03 0.866 – 1.22 0.751 153 853 exclusion phecode
540.11 Acute appendicitis Digestive 1.04 0.86 – 1.25 0.694 126 718 exclusion phecode
550 Abdominal hernia Digestive 0.988 0.94 – 1.04 0.646 2113 7060 exclusion phecode
550.1 Inguinal hernia Digestive 0.903 0.826 – 0.987 0.0242 600 3158 exclusion phecode
550.2 Diaphragmatic hernia Digestive 0.984 0.914 – 1.06 0.664 844 4953 exclusion phecode
550.3 Femoral hernia Digestive 0.913 0.663 – 1.26 0.58 43 246 exclusion phecode
550.4 Umbilical hernia Digestive 0.991 0.896 – 1.1 0.855 473 2487 exclusion phecode
550.5 Ventral hernia Digestive 1.04 0.963 – 1.13 0.303 737 4045 exclusion phecode
550.6 Incisional hernia Digestive 1.01 0.913 – 1.13 0.79 414 2424 exclusion phecode
555
Inflammatory bowel disease and other
Inflammatory bowel disease and other gastroenteritis and colitis
 Digestive 1.05 0.939 – 1.16 0.419 411 2189 exclusion phecode
555.1 Regional enteritis Digestive 1.05 0.912 – 1.21 0.495 245 1242 exclusion phecode
555.2 Ulcerative colitis Digestive 1.09 0.948 – 1.26 0.223 264 1362 exclusion phecode
555.21 Ulcerative colitis (chronic) Digestive 1.08 0.911 – 1.29 0.361 171 765 exclusion phecode
556 Ulceration of the lower GI tract Digestive 0.931 0.81 – 1.07 0.318 274 1013 exclusion phecode
556.1 Ulceration of intestine Digestive 0.909 0.783 – 1.06 0.21 238 856 exclusion phecode
556.11
Angiodysplasia of intestine (without mention of
Angiodysplasia of intestine (without mention of hemorrhage)
 Digestive 0.814 0.651 – 1.02 0.0709 109 397 exclusion phecode
557 Intestinal malabsorption (non-celiac) Digestive 0.879 0.807 – 0.958 0.0032 704 2540 exclusion phecode
557.1 Celiac disease Digestive 0.962 0.794 – 1.16 0.688 143 697 exclusion phecode
558 Noninfectious gastroenteritis Digestive 0.999 0.934 – 1.07 0.97 1195 3873 exclusion phecode
559 Ileostomy status Digestive 1.11 0.964 – 1.28 0.144 233 1200 exclusion phecode
560 Intestinal obstruction without mention of hernia Digestive 0.987 0.917 – 1.06 0.72 952 3476 exclusion phecode
560.1 Paralytic ileus Digestive 1.04 0.943 – 1.15 0.415 492 2136 exclusion phecode
560.2 Impaction of intestine Digestive 0.807 0.667 – 0.976 0.0271 147 612 exclusion phecode
560.3 Peritoneal or intestinal adhesions Digestive 0.946 0.753 – 1.19 0.631 97 365 exclusion phecode
560.4 Other intestinal obstruction Digestive 0.967 0.88 – 1.06 0.485 559 2229 exclusion phecode
561 Symptoms involving digestive system Digestive 0.921 0.852 – 0.996 0.0398 876 3234 exclusion phecode
562 Diverticulosis and diverticulitis Digestive 0.935 0.883 – 0.989 0.0192 2298 3398 exclusion phecode
562.1 Diverticulosis Digestive 0.936 0.884 – 0.991 0.0221 2280 3388 exclusion phecode
562.2 Diverticulitis Digestive 0.844 0.764 – 0.932 0.000791 517 2200 exclusion phecode
564 Functional digestive disorders Digestive 0.992 0.947 – 1.04 0.739 3517 4203 exclusion phecode
564.1 Irritable Bowel Syndrome Digestive 0.951 0.884 – 1.02 0.182 990 3327 exclusion phecode
564.9 Personal history of diseases of digestive system Digestive 0.975 0.908 – 1.05 0.493 1030 3645 exclusion phecode
565 Anal and rectal conditions Digestive 1.03 0.969 – 1.1 0.327 1212 5239 exclusion phecode
565.1 Anal and rectal polyp Digestive 1.05 0.952 – 1.15 0.346 522 2405 exclusion phecode
567 Peritonitis and retroperitoneal infections Digestive 1.04 0.933 – 1.15 0.516 456 2047 exclusion phecode
568 Other disorders of peritoneum Digestive 1.06 0.958 – 1.17 0.261 471 2685 exclusion phecode
568.1
Peritoneal adhesions (postoperative)
Peritoneal adhesions (postoperative) (postinfection)
 Digestive 1.05 0.93 – 1.19 0.42 316 1918 exclusion phecode
569 Other disorders of intestine Digestive 1.01 0.968 – 1.06 0.555 2786 5893 exclusion phecode
569.1 Toxic gastroenteritis and colitis Digestive 1.06 0.864 – 1.3 0.576 114 537 exclusion phecode
569.2 Gastrointestinal complications Digestive 1.06 0.956 – 1.18 0.267 456 2294 exclusion phecode
571 Chronic liver disease and cirrhosis Digestive 1.03 0.972 – 1.09 0.325 1600 5284 exclusion phecode
571.5 Other chronic nonalcoholic liver disease Digestive 1.01 0.956 – 1.07 0.666 1506 5231 exclusion phecode
571.51 Cirrhosis of liver without mention of alcohol Digestive 1.05 0.945 – 1.17 0.354 406 1816 exclusion phecode
571.6 Primary biliary cirrhosis Digestive 1.05 0.811 – 1.36 0.707 77 325 exclusion phecode
571.8
Liver abscess and sequelae of chronic liver
Liver abscess and sequelae of chronic liver disease
 Digestive 1.14 1.02 – 1.28 0.022 377 1678 exclusion phecode
571.81 Portal hypertension Digestive 1.08 0.943 – 1.24 0.26 252 1014 exclusion phecode
572 Ascites (non malignant) Digestive 1.08 1 – 1.17 0.0454 770 3606 exclusion phecode
573 Other disorders of liver Digestive 1.01 0.958 – 1.07 0.701 1837 5497 exclusion phecode
573.1 Chronic passive congestion of liver Digestive 1.04 0.81 – 1.35 0.737 92 227 exclusion phecode
573.2 Liver replaced by transplant Digestive 1.09 0.905 – 1.31 0.369 162 494 exclusion phecode
573.3 Hepatomegaly Digestive 0.985 0.819 – 1.19 0.874 137 880 exclusion phecode
573.4 Acute and subacute necrosis of liver Digestive 1.17 0.969 – 1.41 0.103 144 547 exclusion phecode
573.5 Jaundice (not of newborn) Digestive 1.06 0.946 – 1.19 0.308 375 1678 exclusion phecode
573.6
Nonspecific elevation of levels of transaminase
Nonspecific elevation of levels of transaminase or lactic acid dehydrogenase [LDH]
 Digestive 1.04 0.978 – 1.11 0.194 1180 4499 exclusion phecode
573.7 Abnormal results of function study of liver Digestive 1.03 0.966 – 1.09 0.385 1287 4674 exclusion phecode
573.9 Abnormal serum enzyme levels Digestive 1.06 1 – 1.11 0.0409 1962 5555 exclusion phecode
574 Cholelithiasis and cholecystitis Digestive 1.01 0.943 – 1.07 0.859 1106 6052 exclusion phecode
574.1 Cholelithiasis Digestive 0.98 0.917 – 1.05 0.563 1022 5683 exclusion phecode
574.11 Cholelithiasis with acute cholecystitis Digestive 0.934 0.778 – 1.12 0.461 139 701 exclusion phecode
574.12 Cholelithiasis with other cholecystitis Digestive 1.02 0.871 – 1.19 0.807 180 1091 exclusion phecode
574.2 Calculus of bile duct Digestive 1.03 0.909 – 1.16 0.677 319 1705 exclusion phecode
574.3 Cholecystitis without cholelithiasis Digestive 1.01 0.901 – 1.14 0.826 325 1705 exclusion phecode
575 Other biliary tract disease Digestive 1.01 0.934 – 1.09 0.808 780 4392 exclusion phecode
575.1 Cholangitis Digestive 1.14 0.944 – 1.37 0.176 133 706 exclusion phecode
575.2 Obstruction of bile duct Digestive 1.07 0.919 – 1.26 0.368 192 1199 exclusion phecode
575.6 Cholesterolosis of gallbladder Digestive 0.926 0.713 – 1.2 0.564 62 381 exclusion phecode
575.7 Other disorders of gallbladder Digestive 0.968 0.865 – 1.08 0.579 352 1862 exclusion phecode
575.8 Other disorders of biliary tract Digestive 1.03 0.926 – 1.15 0.569 390 2254 exclusion phecode
575.9
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of biliary tract
 Digestive 0.941 0.756 – 1.17 0.584 106 523 exclusion phecode
577 Diseases of pancreas Digestive 1.06 0.979 – 1.14 0.158 768 4855 exclusion phecode
577.1 Acute pancreatitis Digestive 1.03 0.934 – 1.14 0.53 433 2674 exclusion phecode
577.2 Chronic pancreatitis Digestive 0.961 0.827 – 1.12 0.609 196 1081 exclusion phecode
577.3 Cyst and pseudocyst of pancreas Digestive 1.06 0.91 – 1.23 0.463 206 1299 exclusion phecode
578 Gastrointestinal hemorrhage Digestive 1.01 0.955 – 1.06 0.805 1857 6346 exclusion phecode
578.1 Hematemesis Digestive 0.964 0.832 – 1.12 0.628 220 913 exclusion phecode
578.2 Blood in stool Digestive 0.994 0.931 – 1.06 0.861 1165 4716 exclusion phecode
578.8 Hemorrhage of rectum and anus Digestive 1.04 0.965 – 1.12 0.315 899 3838 exclusion phecode
578.9 Hemorrhage of gastrointestinal tract Digestive 1.03 0.95 – 1.12 0.464 727 2824 exclusion phecode
579 Other symptoms involving abdomen and pelvis Digestive 1.01 0.956 – 1.07 0.669 1494 5792 exclusion phecode
579.2 Splenomegaly Digestive 1.07 0.944 – 1.21 0.3 335 1347 exclusion phecode
579.8 Nonspecific abnormal findings in stool contents Digestive 0.988 0.906 – 1.08 0.794 639 2641 exclusion phecode
580 Nephritis; nephrosis; renal sclerosis Genitourinary 1.09 1.01 – 1.17 0.0199 1099 2676 exclusion phecode
580.1 Glomerulonephritis Genitourinary 1.15 0.983 – 1.34 0.0817 236 728 exclusion phecode
580.11 Proliferative glomerulonephritis Genitourinary 1.09 0.838 – 1.42 0.522 79 262 exclusion phecode
580.12 Non-proliferative glomerulonephritis Genitourinary 1.26 0.922 – 1.72 0.147 64 208 exclusion phecode
580.13 Acute glomerulonephritis, NOS Genitourinary 1.21 0.834 – 1.76 0.314 38 117 exclusion phecode
580.14 Chronic glomerulonephritis, NOS Genitourinary 1.06 0.874 – 1.27 0.573 177 493 exclusion phecode
580.2
Nephrotic syndrome without mention of
Nephrotic syndrome without mention of glomerulonephritis
 Genitourinary 1.2 0.955 – 1.5 0.119 108 414 exclusion phecode
580.3
Nephritis and nephropathy without mention of
Nephritis and nephropathy without mention of glomerulonephritis
 Genitourinary 1.08 0.998 – 1.16 0.0558 953 2183 exclusion phecode
580.31
Nephritis and nephropathy in diseases
Nephritis and nephropathy in diseases classified elsewhere
 Genitourinary 1.07 0.977 – 1.17 0.151 723 1552 exclusion phecode
580.32
Nephritis and nephropathy with pathological
Nephritis and nephropathy with pathological lesion
 Genitourinary 1.11 0.99 – 1.26 0.0719 359 1276 exclusion phecode
580.4 Renal sclerosis, NOS Genitourinary 1.02 0.852 – 1.22 0.829 155 575 exclusion phecode
585 Renal failure Genitourinary 1.09 1.04 – 1.15 0.000324 2990 5042 exclusion phecode
585.1 Acute renal failure Genitourinary 1.11 1.05 – 1.18 0.000126 1961 4223 exclusion phecode
585.2 Renal failure NOS Genitourinary 1.05 0.945 – 1.17 0.348 459 1423 exclusion phecode
585.3 Chronic renal failure [CKD] Genitourinary 1.09 1.03 – 1.15 0.00167 2350 4621 exclusion phecode
585.31 Renal dialysis Genitourinary 1.06 0.945 – 1.18 0.339 442 1294 exclusion phecode
585.32 End stage renal disease Genitourinary 1.08 0.978 – 1.18 0.13 603 1693 exclusion phecode
585.33 Chronic Kidney Disease, Stage III Genitourinary 1.12 1.05 – 1.19 0.00031 1584 3459 exclusion phecode
585.34 Chronic Kidney Disease, Stage IV Genitourinary 1.11 1.01 – 1.23 0.0312 549 1599 exclusion phecode
585.4 Chronic kidney disease, Stage I or II Genitourinary 1.11 1.02 – 1.21 0.0214 694 2009 exclusion phecode
586 Other disorders of the kidney and ureters Genitourinary 1.09 1.04 – 1.14 0.000648 2675 5308 exclusion phecode
586.1 Anatomical abnormatilies of kidney and ureters Genitourinary 1.05 0.868 – 1.28 0.597 120 566 exclusion phecode
586.11 Small kidney Genitourinary 1.1 0.861 – 1.4 0.45 75 385 exclusion phecode
586.12 Vesicoureteral reflux Genitourinary 0.888 0.618 – 1.28 0.52 42 196 exclusion phecode
586.2 Cyst of kidney, acquired Genitourinary 1.06 0.958 – 1.17 0.269 508 2087 exclusion phecode
586.3 Vascular disorders of kidney/hypertrophy Genitourinary 1.09 0.88 – 1.36 0.42 104 329 exclusion phecode
586.4 Stricture/obstruction of ureter Genitourinary 1.02 0.928 – 1.13 0.646 477 2567 exclusion phecode
587 Kidney replaced by transpant Genitourinary 1.07 0.965 – 1.19 0.198 510 1394 exclusion phecode
588 Disorders resulting from impaired renal function Genitourinary 1.07 0.972 – 1.18 0.169 606 1691 exclusion phecode
588.1 Renal osteodystrophy Genitourinary 1.08 0.921 – 1.27 0.338 206 479 exclusion phecode
588.2 Secondary hyperparathyroidism (of renal origin) Genitourinary 1.1 0.983 – 1.22 0.0968 465 1396 exclusion phecode
589 Abnormal results of function study of kidney Genitourinary 1.13 1.03 – 1.25 0.0131 529 1706 exclusion phecode
590 Pyelonephritis Genitourinary 0.988 0.9 – 1.08 0.8 567 2369 exclusion phecode
591 Urinary tract infection Genitourinary 1.01 0.968 – 1.06 0.568 3173 5400 exclusion phecode
592 Cystitis and urethritis Genitourinary 1.02 0.952 – 1.09 0.571 1076 3953 exclusion phecode
592.1 Cystitis Genitourinary 1.03 0.955 – 1.1 0.49 1031 3789 exclusion phecode
592.11 Acute cystitis Genitourinary 1.03 0.948 – 1.12 0.471 718 2693 exclusion phecode
592.12 Chronic cystitis Genitourinary 0.889 0.692 – 1.14 0.356 78 397 exclusion phecode
592.13 Chronic interstitial cystitis Genitourinary 0.971 0.779 – 1.21 0.797 88 623 exclusion phecode
592.2 Urethritis and urethral syndrome Genitourinary 0.964 0.741 – 1.25 0.785 69 384 exclusion phecode
593 Hematuria Genitourinary 1.03 0.972 – 1.09 0.341 1752 5321 exclusion phecode
593.1 Gross hematuria Genitourinary 0.965 0.882 – 1.06 0.439 582 2752 exclusion phecode
593.2 Microscopic hematuria Genitourinary 1.07 0.96 – 1.19 0.224 410 1779 exclusion phecode
594 Urinary calculus Genitourinary 0.964 0.914 – 1.02 0.168 1735 7443 exclusion phecode
594.1 Calculus of kidney Genitourinary 0.965 0.915 – 1.02 0.203 1643 7407 exclusion phecode
594.2 Calculus of lower urinary tract Genitourinary 1.07 0.871 – 1.31 0.53 107 810 exclusion phecode
594.3 Calculus of ureter Genitourinary 0.994 0.899 – 1.1 0.908 444 2740 exclusion phecode
594.8 Renal colic Genitourinary 1.05 0.844 – 1.3 0.684 109 694 exclusion phecode
595 Hydronephrosis Genitourinary 0.949 0.86 – 1.05 0.301 463 3189 exclusion phecode
596 Other disorders of bladder Genitourinary 0.991 0.922 – 1.06 0.798 889 5593 exclusion phecode
596.1 Bladder neck obstruction Genitourinary 0.891 0.717 – 1.11 0.296 102 867 exclusion phecode
596.5 Functional disorders of bladder Genitourinary 0.979 0.894 – 1.07 0.638 551 3469 exclusion phecode
597 Other disorders of urethra and urinary tract Genitourinary 1.07 0.939 – 1.21 0.321 271 2411 exclusion phecode
597.1 Urethral stricture (not specified as infectious) Genitourinary 1.07 0.898 – 1.28 0.451 140 1307 exclusion phecode
597.2 Urinary complications NEC Genitourinary 1.08 0.952 – 1.23 0.225 257 2127 exclusion phecode
597.8 Urethral hypermobility/ISD Genitourinary 0.926 0.648 – 1.32 0.671 34 365 exclusion phecode
598 Abnormal findings on examination of urine Genitourinary 1.05 0.771 – 1.42 0.763 51 315 exclusion phecode
598.4 Other cells and casts in urine Genitourinary 1.06 0.765 – 1.47 0.724 44 285 exclusion phecode
599 Other symptoms/disorders or the urinary system Genitourinary 1.01 0.966 – 1.05 0.699 4132 5084 exclusion phecode
599.1 Urinary obstruction Genitourinary 0.948 0.83 – 1.08 0.436 256 1263 exclusion phecode
599.2 Retention of urine Genitourinary 0.992 0.932 – 1.06 0.804 1445 4497 exclusion phecode
599.3 Dysuria Genitourinary 0.984 0.928 – 1.04 0.601 1547 4655 exclusion phecode
599.4 Urinary incontinence Genitourinary 0.976 0.919 – 1.04 0.435 1516 4465 exclusion phecode
599.5 Frequency of urination and polyuria Genitourinary 0.997 0.942 – 1.05 0.91 1816 4848 exclusion phecode
599.6 Oliguria and anuria Genitourinary 1.01 0.882 – 1.15 0.935 289 942 exclusion phecode
599.7 Urethral discharge Genitourinary 0.876 0.633 – 1.21 0.426 41 285 exclusion phecode
599.8 Other symptoms involving urinary system Genitourinary 1.03 0.971 – 1.09 0.316 1574 4642 exclusion phecode
599.9 Other abnormality of urination Genitourinary 0.956 0.891 – 1.03 0.208 983 4214 exclusion phecode
600 Hyperplasia of prostate Genitourinary 0.979 0.911 – 1.05 0.568 1479 2300 exclusion phecode
601 Inflammatory diseases of prostate Genitourinary 0.965 0.867 – 1.07 0.52 403 2012 exclusion phecode
601.1 Prostatitis Genitourinary 0.936 0.8 – 1.09 0.407 184 1034 exclusion phecode
601.11 Acute prostatitis Genitourinary 1.06 0.769 – 1.45 0.736 45 270 exclusion phecode
601.12 Chronic prostatitis Genitourinary 1.16 0.785 – 1.7 0.463 33 217 exclusion phecode
601.3 Orchitis and epididymitis Genitourinary 1.05 0.874 – 1.27 0.592 150 773 exclusion phecode
601.4 Balanoposthitis Genitourinary 0.953 0.69 – 1.32 0.772 47 238 exclusion phecode
601.8
Other inflammatory disorders of male genital
Other inflammatory disorders of male genital organs
 Genitourinary 1.01 0.784 – 1.29 0.958 69 311 exclusion phecode
602 Other disorders of prostate Genitourinary 0.945 0.777 – 1.15 0.567 115 734 exclusion phecode
602.3 Dysplasia of prostate Genitourinary 0.73 0.476 – 1.12 0.149 22 174 exclusion phecode
603 Other disorders of testis Genitourinary 0.913 0.764 – 1.09 0.315 157 784 exclusion phecode
603.1 Hydrocele Genitourinary 0.899 0.723 – 1.12 0.339 115 552 exclusion phecode
603.2 Spermatocele Genitourinary 0.835 0.628 – 1.11 0.217 59 270 exclusion phecode
604 Disorders of penis Genitourinary 0.923 0.801 – 1.06 0.272 221 1181 exclusion phecode
604.1 Redundant prepuce and phimosis/BXO Genitourinary 1.12 0.844 – 1.49 0.43 52 279 exclusion phecode
604.3 Peyronie's disease Genitourinary 0.82 0.607 – 1.11 0.197 47 361 exclusion phecode
605 Erectile dysfunction [ED] Genitourinary 0.995 0.926 – 1.07 0.887 1325 2135 exclusion phecode
608 Other disorders of male genital organs Genitourinary 1.01 0.925 – 1.11 0.756 595 2271 exclusion phecode
609 Male infertility and abnormal spermatozoa Genitourinary 0.859 0.711 – 1.04 0.117 133 796 exclusion phecode
609.1 Infertility, male Genitourinary 0.811 0.636 – 1.03 0.0906 92 539 exclusion phecode
609.11 Azoospermia and oligospermia Genitourinary 0.721 0.457 – 1.14 0.159 26 168 exclusion phecode
609.2 Abnormal spermatozoa Genitourinary 1 0.751 – 1.33 0.997 48 302 exclusion phecode
610 Benign mammary dysplasias Genitourinary 0.897 0.831 – 0.967 0.00466 1011 2371 exclusion phecode
610.1 Cystic mastopathy Genitourinary 0.878 0.792 – 0.975 0.0144 438 1978 exclusion phecode
610.2 Fibroadenosis of breast Genitourinary 0.701 0.428 – 1.15 0.158 25 90 exclusion phecode
610.4 Benign neoplasm of breast Genitourinary 0.915 0.841 – 0.994 0.036 778 2335 exclusion phecode
610.8 Other specified benign mammary dysplasias Genitourinary 0.852 0.754 – 0.962 0.0098 310 1661 exclusion phecode
611 Abnormal findings on mammogram or breast exam Genitourinary 0.923 0.869 – 0.981 0.00962 1907 2962 exclusion phecode
611.1 Abnormal mammogram Genitourinary 0.921 0.862 – 0.984 0.0154 1526 2367 exclusion phecode
611.11 Mammographic microcalcification Genitourinary 0.89 0.794 – 0.997 0.0446 381 1477 exclusion phecode
611.3 Lump or mass in breast Genitourinary 0.907 0.845 – 0.973 0.00679 1145 2935 exclusion phecode
612
Breast conditions, congenital or relating to
Breast conditions, congenital or relating to hormones
 Genitourinary 0.883 0.778 – 1 0.0518 307 1665 exclusion phecode
612.1 Galactorrhea Genitourinary 1.09 0.777 – 1.53 0.615 45 233 exclusion phecode
612.2 Hypertrophy of breast (Gynecomastia) Genitourinary 0.857 0.742 – 0.992 0.038 226 1259 exclusion phecode
612.3 Congenital anomalies of breast Genitourinary 0.37 0.221 – 0.62 0.000159 30 124 exclusion phecode
613 Other nonmalignant breast conditions Genitourinary 0.967 0.904 – 1.03 0.333 1150 3967 exclusion phecode
613.1 Inflammatory disease of breast Genitourinary 1.02 0.862 – 1.22 0.788 163 1014 exclusion phecode
613.5 Mastodynia Genitourinary 0.916 0.834 – 1.01 0.0652 553 2939 exclusion phecode
613.7 Other signs and symptoms in breast Genitourinary 0.965 0.847 – 1.1 0.596 283 1583 exclusion phecode
613.8 Other specified disorders of breast Genitourinary 1.07 0.933 – 1.23 0.335 245 1580 exclusion phecode
613.9 Breast disorder NOS Genitourinary 0.918 0.825 – 1.02 0.115 394 2400 exclusion phecode
614 Inflammatory diseases of female pelvic organs Genitourinary 0.931 0.87 – 0.997 0.0404 1206 3285 exclusion phecode
614.1
Pelvic peritoneal adhesions, female
Pelvic peritoneal adhesions, female (postoperative) (postinfection)
 Genitourinary 0.94 0.741 – 1.19 0.61 81 534 exclusion phecode
614.3 Pelvic inflammatory disease (PID) Genitourinary 1.15 0.955 – 1.4 0.138 145 768 exclusion phecode
614.31 Acute inflammatory pelvic disease Genitourinary 1.01 0.61 – 1.67 0.972 24 139 exclusion phecode
614.32 Chronic inflammatory pelvic disease Genitourinary 1.14 0.823 – 1.59 0.425 54 257 exclusion phecode
614.33 Pelvic inflammatory disease, NOS Genitourinary 1.37 1.06 – 1.77 0.0145 82 406 exclusion phecode
614.4 Inflammatory diseases of uterus, except cervix Genitourinary 0.938 0.698 – 1.26 0.67 56 291 exclusion phecode
614.5
Inflammatory disease of cervix, vagina, and
Inflammatory disease of cervix, vagina, and vulva
 Genitourinary 0.917 0.854 – 0.984 0.016 1072 3257 exclusion phecode
614.51 Cervicitis and endocervicitis Genitourinary 0.841 0.666 – 1.06 0.147 83 476 exclusion phecode
614.52 Vaginitis and vulvovaginitis Genitourinary 0.91 0.845 – 0.981 0.0136 935 3148 exclusion phecode
614.53 Cyst or abscess of Bartholin's gland Genitourinary 1.06 0.756 – 1.48 0.737 45 266 exclusion phecode
614.54 Abscess or ulceration of vulva Genitourinary 0.845 0.66 – 1.08 0.181 73 423 exclusion phecode
615 Endometriosis Genitourinary 0.974 0.87 – 1.09 0.65 368 2372 exclusion phecode
618 Genital prolapse Genitourinary 0.96 0.87 – 1.06 0.416 459 3293 exclusion phecode
618.1 Prolapse of vaginal walls Genitourinary 0.898 0.792 – 1.02 0.0904 275 2454 exclusion phecode
618.2 Uterine/Uterovaginal prolapse Genitourinary 0.89 0.735 – 1.08 0.235 122 970 exclusion phecode
618.5 Prolapse of vaginal vault after hysterectomy Genitourinary 0.878 0.638 – 1.21 0.422 38 538 exclusion phecode
618.6 Vaginal enterocele, congenital or acquired Genitourinary 1.06 0.862 – 1.3 0.593 108 769 exclusion phecode
619 Noninflammatory female genital disorders Genitourinary 0.923 0.868 – 0.982 0.0114 1639 3064 exclusion phecode
619.1
Noninflammatory disorders of ovary, fallopian
Noninflammatory disorders of ovary, fallopian tube, and broad ligament
 Genitourinary 0.837 0.742 – 0.945 0.00401 340 1890 exclusion phecode
619.2 Disorders of uterus, NEC Genitourinary 0.94 0.799 – 1.11 0.456 178 1004 exclusion phecode
619.3 Noninflammatory disorders of cervix Genitourinary 0.88 0.737 – 1.05 0.161 149 742 exclusion phecode
619.4 Noninflammatory disorders of vagina Genitourinary 0.929 0.857 – 1.01 0.0718 811 2993 exclusion phecode
619.5 Noninflammatory disorders of vulva and perineum Genitourinary 0.978 0.877 – 1.09 0.693 384 2038 exclusion phecode
620 Dysplasia of female genital organs Genitourinary 0.914 0.746 – 1.12 0.385 115 694 exclusion phecode
620.1 Dysplasia of cervix Genitourinary 0.95 0.714 – 1.26 0.722 62 303 exclusion phecode
621 Endometrial hyperplasia Genitourinary 0.768 0.635 – 0.929 0.00663 131 671 exclusion phecode
622 Polyp of female genital organs Genitourinary 0.902 0.816 – 0.997 0.0434 466 2518 exclusion phecode
622.1 Polyp of corpus uteri Genitourinary 0.918 0.819 – 1.03 0.138 360 1947 exclusion phecode
622.2 Mucous polyp of cervix Genitourinary 0.792 0.661 – 0.95 0.012 150 783 exclusion phecode
623 Hypertrophy of female genital organs Genitourinary 0.97 0.856 – 1.1 0.64 292 1503 exclusion phecode
624 Symptoms involving female genital tract Genitourinary 0.964 0.867 – 1.07 0.5 450 1952 exclusion phecode
624.1 Dystrophy of female genital tract Genitourinary 1 0.772 – 1.3 0.984 66 378 exclusion phecode
624.2 Atrophy of female genital tract Genitourinary 1.09 0.712 – 1.67 0.688 18 133 exclusion phecode
624.9 stress incontinence, female Genitourinary 0.965 0.874 – 1.07 0.477 491 2341 exclusion phecode
625
Pain and other symptoms associated with female
Pain and other symptoms associated with female genital organs
 Genitourinary 0.922 0.866 – 0.982 0.0118 1662 2683 exclusion phecode
625.1 Dyspareunia Genitourinary 0.95 0.841 – 1.07 0.408 322 1786 exclusion phecode
626
Disorders of menstruation and other abnormal
Disorders of menstruation and other abnormal bleeding from female genital tract
 Genitourinary 0.933 0.873 – 0.997 0.042 1836 2105 exclusion phecode
626.1 Irregular menstrual cycle/bleeding Genitourinary 0.925 0.861 – 0.995 0.0358 1477 1944 exclusion phecode
626.11 Absent or infrequent menstruation Genitourinary 0.966 0.857 – 1.09 0.571 378 1137 exclusion phecode
626.12 Excessive or frequent menstruation Genitourinary 0.879 0.802 – 0.965 0.00659 745 1543 exclusion phecode
626.13 Irregular menstrual cycle Genitourinary 0.9 0.819 – 0.988 0.0271 697 1626 exclusion phecode
626.14 Irregular menstrual bleeding Genitourinary 0.935 0.827 – 1.06 0.288 364 1148 exclusion phecode
626.15 Infertility, female, associated with anovulation Genitourinary 1.01 0.84 – 1.21 0.927 156 591 exclusion phecode
626.2 Dysmenorrhea Genitourinary 0.968 0.863 – 1.09 0.578 437 1253 exclusion phecode
626.4 Premenstrual tension syndromes Genitourinary 0.891 0.72 – 1.1 0.289 121 469 exclusion phecode
626.8 Infertility, female Genitourinary 1.04 0.91 – 1.2 0.534 285 885 exclusion phecode
627 Menopausal and postmenopausal disorders Genitourinary 0.857 0.798 – 0.92 2.09e-05 1348 1938 exclusion phecode
627.1 Postmenopausal bleeding Genitourinary 0.866 0.768 – 0.977 0.0189 334 1413 exclusion phecode
627.2 Symptomatic menopause Genitourinary 0.866 0.798 – 0.94 0.000566 896 1823 exclusion phecode
627.21 Symptomatic artificial menopause Genitourinary 0.853 0.632 – 1.15 0.296 54 199 exclusion phecode
627.22
Need for Hormone replacement therapy
Need for Hormone replacement therapy (postmenopausal)
 Genitourinary 0.942 0.766 – 1.16 0.57 98 564 exclusion phecode
627.3 Postmenopausal atrophic vaginitis Genitourinary 0.884 0.78 – 1 0.0537 303 1325 exclusion phecode
627.4 Premenopausal menorrhagia Genitourinary 0.952 0.783 – 1.16 0.619 131 505 exclusion phecode
627.5 Premature menopause and other ovarian failure Genitourinary 0.746 0.593 – 0.938 0.012 96 428 exclusion phecode
628 Ovarian cyst Genitourinary 0.885 0.804 – 0.974 0.0126 606 1825 exclusion phecode
634 Miscarriage; stillbirth Pregnancy Complications 0.99 0.868 – 1.13 0.876 280 1469 exclusion phecode
634.1 Missed abortion/Hydatidiform mole Pregnancy Complications 0.833 0.664 – 1.04 0.114 99 550 exclusion phecode
634.3 Ectopic pregnancy Pregnancy Complications 0.982 0.688 – 1.4 0.919 36 215 exclusion phecode
635
Hemorrhage during pregnancy; childbirth and
Hemorrhage during pregnancy; childbirth and postpartum
 Pregnancy Complications 1.02 0.871 – 1.19 0.842 199 1002 exclusion phecode
635.2
Antepartum hemorrhage, abruptio placentae, and
Antepartum hemorrhage, abruptio placentae, and placenta previa
 Pregnancy Complications 1.11 0.919 – 1.34 0.282 141 691 exclusion phecode
635.3 Placenta previa and abruptio placenta Pregnancy Complications 0.92 0.74 – 1.14 0.451 94 550 exclusion phecode
636
Early or threatened labor; hemorrhage in early
Early or threatened labor; hemorrhage in early pregnancy
 Pregnancy Complications 1.02 0.909 – 1.15 0.701 378 1470 exclusion phecode
636.1 Threatened premature labor Pregnancy Complications 1.02 0.843 – 1.23 0.838 139 682 exclusion phecode
636.2 Early onset of delivery Pregnancy Complications 0.978 0.798 – 1.2 0.83 119 552 exclusion phecode
636.3 Hemorrhage in early pregnancy Pregnancy Complications 1.16 0.973 – 1.39 0.098 165 825 exclusion phecode
636.8 Cervical incompetence Pregnancy Complications 0.845 0.523 – 1.36 0.49 24 154 exclusion phecode
637
Short gestation; low birth weight; and fetal
Short gestation; low birth weight; and fetal growth retardation
 Pregnancy Complications 1.1 0.76 – 1.6 0.602 33 159 exclusion phecode
642
Hypertension complicating pregnancy
Hypertension complicating pregnancy, childbirth, and the puerperium
 Pregnancy Complications 1.1 0.937 – 1.29 0.248 193 1228 exclusion phecode
642.1 Preeclampsia and eclampsia Pregnancy Complications 1.15 0.923 – 1.43 0.215 109 682 exclusion phecode
643 Excessive vomiting in pregnancy Pregnancy Complications 1.15 0.91 – 1.44 0.247 91 560 exclusion phecode
643.1 Hyperemesis gravidarum Pregnancy Complications 0.997 0.707 – 1.41 0.987 43 257 exclusion phecode
644 Anemia during pregnancy Pregnancy Complications 0.854 0.67 – 1.09 0.199 80 512 exclusion phecode
646 Other complications of pregnancy NEC Pregnancy Complications 1.03 0.897 – 1.18 0.681 269 1266 exclusion phecode
647
Infectious and parasitic complications
Infectious and parasitic complications affecting pregnancy
 Pregnancy Complications 1.1 0.84 – 1.44 0.485 72 488 exclusion phecode
647.1
Infections of genitourinary tract during
Infections of genitourinary tract during pregnancy
 Pregnancy Complications 0.978 0.761 – 1.26 0.86 78 464 exclusion phecode
647.3 Major puerperal infection Pregnancy Complications 0.844 0.522 – 1.36 0.488 18 151 exclusion phecode
649
Other conditions or status of the mother
Other conditions or status of the mother complicating pregnancy, childbirth, or the puerperium
 Pregnancy Complications 1.06 0.95 – 1.19 0.281 424 1499 exclusion phecode
649.1
Diabetes or abnormal glucose tolerance
Diabetes or abnormal glucose tolerance complicating pregnancy
 Pregnancy Complications 0.967 0.845 – 1.11 0.623 263 1303 exclusion phecode
653
Problems associated with amniotic cavity and
Problems associated with amniotic cavity and membranes
 Pregnancy Complications 1.02 0.869 – 1.19 0.826 199 1105 exclusion phecode
654.1
Abnormality of organs and soft tissues of
Abnormality of organs and soft tissues of pelvis complicating pregnancy, childbirth, or the puerperium
 Pregnancy Complications 1.19 0.909 – 1.55 0.208 70 402 exclusion phecode
654.2 Rhesus isoimmunization in pregnancy Pregnancy Complications 1.07 0.825 – 1.39 0.608 76 410 exclusion phecode
655
Known or suspected fetal abnormality affecting
Known or suspected fetal abnormality affecting management of mother
 Pregnancy Complications 1.06 0.957 – 1.17 0.274 547 1875 exclusion phecode
655.1 Abnormality in fetal heart rate or rhythm Pregnancy Complications 1.03 0.888 – 1.2 0.677 225 1051 exclusion phecode
656 Other perinatal conditions of fetus or newborn Pregnancy Complications 1.03 0.906 – 1.17 0.651 300 1362 exclusion phecode
656.2 Respiratory conditions of fetus and newborn Pregnancy Complications 0.883 0.544 – 1.43 0.616 24 143 exclusion phecode
669 Complications of labor and delivery NEC Pregnancy Complications 1.06 0.927 – 1.2 0.417 304 1347 exclusion phecode
671
Venous/cerebrovascular complications embolism
Venous/cerebrovascular complications embolism in pregnancy and the puerperium
 Pregnancy Complications 1.03 0.801 – 1.33 0.801 72 445 exclusion phecode
674 Other complications of the puerperium NEC Pregnancy Complications 0.995 0.724 – 1.37 0.976 49 343 exclusion phecode
676
Other disorders of the breast associated with
Other disorders of the breast associated with childbirth and disorders of lactation
 Pregnancy Complications 1.08 0.838 – 1.39 0.561 83 404 exclusion phecode
681 Superficial cellulitis and abscess Dermatologic 1.01 0.964 – 1.06 0.658 2423 6666 exclusion phecode
681.1 Cellulitis and abscess of fingers/toes Dermatologic 1.03 0.942 – 1.12 0.523 637 2566 exclusion phecode
681.2 Cellulitis and abscess of face/neck Dermatologic 1.05 0.934 – 1.18 0.419 343 1895 exclusion phecode
681.3 Cellulitis and abscess of arm/hand Dermatologic 1.01 0.938 – 1.08 0.85 969 3791 exclusion phecode
681.5 Cellulitis and abscess of leg, except foot Dermatologic 1.03 0.961 – 1.1 0.413 1048 3951 exclusion phecode
681.6 Cellulitis and abscess of foot, toe Dermatologic 1.05 0.97 – 1.13 0.245 867 3321 exclusion phecode
681.7 Cellulitis and abscess of trunk Dermatologic 1.01 0.925 – 1.1 0.806 584 2935 exclusion phecode
686
Other local infections of skin and subcutaneous
Other local infections of skin and subcutaneous tissue
 Dermatologic 1.06 0.986 – 1.14 0.113 872 4006 exclusion phecode
686.1 Carbuncle and furuncle Dermatologic 1.08 0.928 – 1.25 0.335 226 1160 exclusion phecode
686.2 Impetigo Dermatologic 0.952 0.803 – 1.13 0.575 165 827 exclusion phecode
686.3 Pilonidal cyst Dermatologic 1.1 0.821 – 1.47 0.528 55 366 exclusion phecode
686.4 Pyogenic granuloma Dermatologic 0.854 0.619 – 1.18 0.335 49 270 exclusion phecode
686.5 Pyoderma Dermatologic 0.984 0.639 – 1.52 0.943 25 132 exclusion phecode
687 Symptoms affecting skin Dermatologic 0.915 0.841 – 0.994 0.0367 683 2902 exclusion phecode
687.1 Rash and other nonspecific skin eruption Dermatologic 0.956 0.912 – 1 0.064 2662 5505 exclusion phecode
687.3 Changes in skin texture Dermatologic 1.04 0.895 – 1.22 0.579 194 947 exclusion phecode
687.4 Disturbance of skin sensation Dermatologic 0.943 0.897 – 0.993 0.0247 2143 5453 exclusion phecode
689 Disorder of skin and subcutaneous tissue NOS Dermatologic 1 0.959 – 1.05 0.953 3310 6350 exclusion phecode
690 Erythematosquamous dermatosis Dermatologic 0.948 0.9 – 0.998 0.0434 2038 5496 exclusion phecode
690.1 Seborrheic dermatitis Dermatologic 0.948 0.901 – 0.999 0.0446 2037 5491 exclusion phecode
691 Congenital anomalies of skin Dermatologic 0.89 0.765 – 1.03 0.129 204 972 exclusion phecode
691.3 Congenital pigmentary anomalies of skin Dermatologic 0.981 0.562 – 1.71 0.945 14 99 exclusion phecode
694 Dyschromia and Vitiligo Dermatologic 0.931 0.856 – 1.01 0.0977 661 3213 exclusion phecode
694.1 Vitiligo Dermatologic 1.01 0.761 – 1.33 0.968 54 313 exclusion phecode
694.2 Other dyschromia Dermatologic 0.914 0.835 – 1 0.0506 579 2868 exclusion phecode
694.3 Vascular disorders of skin Dermatologic 1.16 0.806 – 1.68 0.419 40 136 exclusion phecode
695 Erythematous conditions Dermatologic 0.912 0.861 – 0.967 0.00209 1480 5252 exclusion phecode
695.1 Toxic erythema Dermatologic 0.706 0.47 – 1.06 0.0933 25 144 exclusion phecode
695.2 Bullous dermatoses Dermatologic 0.963 0.636 – 1.46 0.86 32 141 exclusion phecode
695.3 Rosacea Dermatologic 0.895 0.822 – 0.974 0.0105 643 3142 exclusion phecode
695.4 Lupus (localized and systemic) Dermatologic 0.996 0.854 – 1.16 0.958 210 1010 exclusion phecode
695.41 Cutaneous lupus erythematosus Dermatologic 0.964 0.763 – 1.22 0.757 89 362 exclusion phecode
695.42 Systemic lupus erythematosus Dermatologic 0.998 0.849 – 1.17 0.979 195 960 exclusion phecode
695.7 Prurigo and Lichen Dermatologic 0.918 0.789 – 1.07 0.264 210 1113 exclusion phecode
695.8 Other specified erythematous conditions Dermatologic 0.909 0.81 – 1.02 0.102 358 1531 exclusion phecode
695.81 Erythema nodosum Dermatologic 0.82 0.5 – 1.34 0.43 23 82 exclusion phecode
695.9 Unspecified erythematous condition Dermatologic 0.915 0.802 – 1.04 0.189 266 1310 exclusion phecode
696 Psoriasis and related disorders Dermatologic 0.927 0.838 – 1.03 0.146 432 2464 exclusion phecode
696.3 Pityriasis Dermatologic 0.975 0.67 – 1.42 0.895 28 151 exclusion phecode
696.4 Psoriasis Dermatologic 0.919 0.827 – 1.02 0.118 404 2354 exclusion phecode
696.41 Psoriasis vulgaris Dermatologic 0.912 0.818 – 1.02 0.0975 383 2180 exclusion phecode
696.42 Psoriatic arthropathy Dermatologic 0.991 0.793 – 1.24 0.937 90 499 exclusion phecode
697 Sarcoidosis Dermatologic 1.03 0.831 – 1.28 0.783 95 618 exclusion phecode
698 Pruritus and related conditions Dermatologic 0.981 0.911 – 1.06 0.61 859 4437 exclusion phecode
700 Corns and callosities Dermatologic 0.996 0.918 – 1.08 0.924 798 2369 exclusion phecode
701
Other hypertrophic and atrophic conditions of
Other hypertrophic and atrophic conditions of skin
 Dermatologic 0.968 0.923 – 1.01 0.169 2543 6601 exclusion phecode
701.1 Keratoderma, acquired Dermatologic 0.994 0.861 – 1.15 0.939 246 1144 exclusion phecode
701.2 Scar conditions and fibrosis of skin Dermatologic 0.896 0.816 – 0.983 0.0204 522 3590 exclusion phecode
701.3 Circumscribed scleroderma Dermatologic 0.993 0.842 – 1.17 0.932 168 970 exclusion phecode
701.4 Keloid scar Dermatologic 1.02 0.864 – 1.21 0.792 166 1007 exclusion phecode
701.5 Abnormal granulation tissue Dermatologic 0.94 0.77 – 1.15 0.547 120 729 exclusion phecode
702
Degenerative skin conditions and other
Degenerative skin conditions and other dermatoses
 Dermatologic 0.965 0.918 – 1.01 0.168 2633 4726 exclusion phecode
702.1 Actinic keratosis Dermatologic 0.965 0.91 – 1.02 0.22 1653 4703 exclusion phecode
702.2 Seborrheic keratosis Dermatologic 0.953 0.905 – 1 0.0649 2123 5690 exclusion phecode
702.4 Degenerative skin disorders Dermatologic 1.19 0.828 – 1.7 0.353 32 188 exclusion phecode
703 Diseases of nail, NOS Dermatologic 1.03 0.957 – 1.12 0.396 823 3258 exclusion phecode
703.1 Ingrowing nail Dermatologic 0.96 0.868 – 1.06 0.421 459 2072 exclusion phecode
704 Diseases of hair and hair follicles Dermatologic 0.971 0.911 – 1.04 0.37 1140 5585 exclusion phecode
704.1 Alopecia Dermatologic 1 0.91 – 1.11 0.935 466 2499 exclusion phecode
704.11 Alopecia Areata Dermatologic 1.25 0.853 – 1.82 0.255 31 165 exclusion phecode
704.12 Telogen effluvium Dermatologic 0.758 0.476 – 1.21 0.243 24 89 exclusion phecode
704.2 Hirsutism Dermatologic 1 0.807 – 1.25 0.981 102 570 exclusion phecode
704.8
Other specified diseases of hair and hair
Other specified diseases of hair and hair follicles
 Dermatologic 0.97 0.894 – 1.05 0.463 699 3629 exclusion phecode
705 Disorders of sweat glands Dermatologic 0.979 0.843 – 1.14 0.776 218 1118 exclusion phecode
705.1 Dyshidrosis Dermatologic 0.907 0.694 – 1.19 0.474 65 290 exclusion phecode
705.3 Hidradenitis Dermatologic 0.998 0.778 – 1.28 0.99 79 423 exclusion phecode
705.8 Hyperhidrosis Dermatologic 1.05 0.947 – 1.17 0.347 450 2123 exclusion phecode
706 Diseases of sebaceous glands Dermatologic 0.983 0.937 – 1.03 0.478 2355 6941 exclusion phecode
706.1 Acne Dermatologic 0.977 0.908 – 1.05 0.534 956 4030 exclusion phecode
706.2 Sebaceous cyst Dermatologic 0.96 0.898 – 1.03 0.225 1086 4960 exclusion phecode
706.3 Seborrhea Dermatologic 1.1 0.748 – 1.61 0.636 28 121 exclusion phecode
706.8 Other specified diseases of sebaceous glands Dermatologic 0.97 0.897 – 1.05 0.449 783 3173 exclusion phecode
707 Chronic ulcer of skin Dermatologic 1.04 0.974 – 1.11 0.251 1181 5443 exclusion phecode
707.1 Decubitus ulcer Dermatologic 1.12 0.994 – 1.25 0.0639 362 1773 exclusion phecode
707.2 Chronic ulcer of leg or foot Dermatologic 1.06 0.966 – 1.15 0.228 624 2446 exclusion phecode
707.3 Chronic ulcer of unspecified site Dermatologic 1 0.919 – 1.09 0.964 605 3452 exclusion phecode
709 Diffuse diseases of connective tissue Dermatologic 0.949 0.862 – 1.05 0.29 499 2493 exclusion phecode
709.2 Sicca syndrome Dermatologic 0.924 0.781 – 1.09 0.361 164 801 exclusion phecode
709.3 Systemic sclerosis Dermatologic 1.04 0.808 – 1.33 0.776 81 360 exclusion phecode
709.5 Dermatomyositis Dermatologic 0.973 0.656 – 1.44 0.893 34 173 exclusion phecode
709.6
Other specified diffuse diseases of connective
Other specified diffuse diseases of connective tissue
 Dermatologic 0.78 0.543 – 1.12 0.179 34 111 exclusion phecode
709.7 Unspecified diffuse connective tissue disease Dermatologic 0.958 0.849 – 1.08 0.48 321 1627 exclusion phecode
710
Osteomyelitis, periostitis, and other
Osteomyelitis, periostitis, and other infections involving bone
 Musculoskeletal 1.02 0.925 – 1.13 0.662 464 2238 exclusion phecode
710.1 Osteomyelitis Musculoskeletal 1.04 0.94 – 1.15 0.444 453 2162 exclusion phecode
710.11 Acute osteomyelitis Musculoskeletal 0.989 0.865 – 1.13 0.873 274 1196 exclusion phecode
710.12 Chronic osteomyelitis Musculoskeletal 0.98 0.847 – 1.13 0.791 218 1083 exclusion phecode
710.19 Unspecified osteomyelitis Musculoskeletal 1.05 0.945 – 1.16 0.376 430 2084 exclusion phecode
711 Arthropathy associated with infections Musculoskeletal 0.872 0.732 – 1.04 0.127 153 707 exclusion phecode
711.1 Pyogenic arthritis Musculoskeletal 0.965 0.784 – 1.19 0.734 113 515 exclusion phecode
712 Infective connective tissue disorders Musculoskeletal 0.908 0.715 – 1.15 0.428 79 309 exclusion phecode
713
Arthropathy associated with other disorders
Arthropathy associated with other disorders classified elsewhere
 Musculoskeletal 1.15 0.971 – 1.36 0.106 175 827 exclusion phecode
713.5
Arthropathy associated with neurological
Arthropathy associated with neurological disorders
 Musculoskeletal 1.12 0.923 – 1.37 0.244 133 621 exclusion phecode
714
Rheumatoid arthritis and other inflammatory
Rheumatoid arthritis and other inflammatory polyarthropathies
 Musculoskeletal 0.998 0.916 – 1.09 0.965 652 3231 exclusion phecode
714.1 Rheumatoid arthritis Musculoskeletal 0.964 0.874 – 1.06 0.46 492 2594 exclusion phecode
714.2 Juvenile rheumatoid arthritis Musculoskeletal 1.2 0.802 – 1.81 0.37 23 166 exclusion phecode
715 Other inflammatory spondylopathies Musculoskeletal 0.946 0.85 – 1.05 0.306 423 2084 exclusion phecode
715.1 Sacroiliitis NEC Musculoskeletal 1.06 0.845 – 1.32 0.633 94 448 exclusion phecode
715.2 Ankylosing spondylitis Musculoskeletal 0.826 0.622 – 1.1 0.187 51 378 exclusion phecode
716 Other arthropathies Musculoskeletal 0.972 0.929 – 1.02 0.219 3704 5406 exclusion phecode
716.1 Unspecified polyarthropathy or polyarthritis Musculoskeletal 0.859 0.667 – 1.11 0.241 76 348 exclusion phecode
716.2 Unspecified monoarthritis Musculoskeletal 0.817 0.587 – 1.14 0.231 44 207 exclusion phecode
716.9 Arthropathy NOS Musculoskeletal 0.971 0.928 – 1.02 0.2 3674 5405 exclusion phecode
717 Polymyalgia Rheumatica Musculoskeletal 1.07 0.855 – 1.33 0.575 90 653 exclusion phecode
720 Spinal stenosis Musculoskeletal 0.94 0.882 – 1 0.0565 1244 4947 exclusion phecode
720.1 Spinal stenosis of lumbar region Musculoskeletal 0.92 0.856 – 0.988 0.022 965 4132 exclusion phecode
721 Spondylosis and allied disorders Musculoskeletal 0.946 0.897 – 0.998 0.0437 1895 5752 exclusion phecode
721.1 Spondylosis without myelopathy Musculoskeletal 0.944 0.894 – 0.997 0.0387 1801 5681 exclusion phecode
721.2 Spondylosis with myelopathy Musculoskeletal 0.908 0.794 – 1.04 0.163 248 1513 exclusion phecode
721.8 Other allied disorders of spine Musculoskeletal 0.837 0.67 – 1.05 0.117 100 534 exclusion phecode
722 Intervertebral disc disorders Musculoskeletal 0.935 0.887 – 0.986 0.0129 1910 6009 exclusion phecode
722.1 Displacement of intervertebral disc Musculoskeletal 0.934 0.874 – 0.998 0.0423 1084 5472 exclusion phecode
722.3 Schmorl's nodes Musculoskeletal 0.678 0.473 – 0.971 0.0341 48 184 exclusion phecode
722.6 Degeneration of intervertebral disc Musculoskeletal 0.94 0.883 – 0.999 0.0477 1309 5423 exclusion phecode
722.7 Intervertebral disc disorder with myelopathy Musculoskeletal 1.01 0.844 – 1.21 0.895 133 829 exclusion phecode
722.8 Postlaminectomy syndrome Musculoskeletal 1.13 0.92 – 1.38 0.249 112 731 exclusion phecode
722.9 Other and unspecified disc disorder Musculoskeletal 0.928 0.849 – 1.02 0.105 561 3499 exclusion phecode
723 Other disorders of cervical region Musculoskeletal 0.911 0.805 – 1.03 0.14 309 1688 exclusion phecode
723.1 Torticollis Musculoskeletal 0.86 0.678 – 1.09 0.212 80 450 exclusion phecode
724 Other and unspecified disorders of back Musculoskeletal 0.942 0.887 – 1 0.0532 1373 5691 exclusion phecode
724.1 Disorders of sacrum Musculoskeletal 0.927 0.859 – 1 0.0499 820 3945 exclusion phecode
724.2 Disorders of coccyx Musculoskeletal 0.872 0.733 – 1.04 0.122 173 792 exclusion phecode
724.8 Other symptoms referable to back Musculoskeletal 0.885 0.786 – 0.996 0.0428 334 1677 exclusion phecode
724.9 Other unspecified back disorders Musculoskeletal 0.969 0.87 – 1.08 0.56 397 2387 exclusion phecode
726 Peripheral enthesopathies and allied syndromes Musculoskeletal 0.911 0.869 – 0.954 8.29e-05 3469 4264 exclusion phecode
726.1 Enthesopathy Musculoskeletal 0.913 0.868 – 0.961 0.00049 2574 4247 exclusion phecode
726.2 Synoviopathy Musculoskeletal 0.9 0.801 – 1.01 0.074 361 1468 exclusion phecode
726.3 Bursitis Musculoskeletal 0.909 0.836 – 0.987 0.0234 753 2501 exclusion phecode
726.4 Calcaneal spur; Exostosis NOS Musculoskeletal 0.912 0.818 – 1.02 0.101 421 1729 exclusion phecode
727 Other disorders of synovium, tendon, and bursa Musculoskeletal 0.901 0.856 – 0.948 6.4e-05 2554 4242 exclusion phecode
727.1 Synovitis and tenosynovitis Musculoskeletal 0.899 0.84 – 0.963 0.00227 1146 3539 exclusion phecode
727.2 Bursitis disorders Musculoskeletal 0.9 0.748 – 1.08 0.262 157 632 exclusion phecode
727.4 Ganglion and cyst of synovium, tendon, and bursa Musculoskeletal 0.935 0.847 – 1.03 0.178 498 2040 exclusion phecode
727.5 Rupture of synovium Musculoskeletal 0.893 0.746 – 1.07 0.215 153 652 exclusion phecode
727.6 Rupture of tendon, nontraumatic Musculoskeletal 0.876 0.812 – 0.946 0.000708 872 3042 exclusion phecode
727.7 Contracture of tendon (sheath) Musculoskeletal 0.898 0.755 – 1.07 0.224 156 846 exclusion phecode
727.8 Plica syndrome Musculoskeletal 1 0.67 – 1.51 0.981 35 147 exclusion phecode
728 Disorders of muscle, ligament, and fascia Musculoskeletal 0.967 0.911 – 1.03 0.273 1559 4115 exclusion phecode
728.1 Muscular calcification and ossification Musculoskeletal 1.03 0.667 – 1.6 0.887 27 132 exclusion phecode
728.2 Laxity of ligament or hypermobility syndrome Musculoskeletal 0.913 0.73 – 1.14 0.43 100 409 exclusion phecode
728.7 Fasciitis Musculoskeletal 0.935 0.873 – 1 0.0539 1095 3372 exclusion phecode
728.71
Contracture of palmar fascia [Dupuytren's
Contracture of palmar fascia [Dupuytren's disease]
 Musculoskeletal 0.886 0.75 – 1.05 0.153 171 765 exclusion phecode
729 Other disorders of soft tissues Musculoskeletal 0.979 0.92 – 1.04 0.507 1390 3823 exclusion phecode
729.1 Rheumatism, unspecified and fibrositis Musculoskeletal 0.814 0.542 – 1.22 0.322 30 116 exclusion phecode
729.3 Panniculitis Musculoskeletal 1.16 0.81 – 1.65 0.422 43 170 exclusion phecode
729.7 Nontraumatic compartment syndrome Musculoskeletal 0.671 0.42 – 1.07 0.0957 19 100 exclusion phecode
731
Osteitis deformans and osteopathies associated
Osteitis deformans and osteopathies associated with other disorders classified elsewhere
 Musculoskeletal 0.991 0.799 – 1.23 0.932 118 540 exclusion phecode
732 Osteochondropathies Musculoskeletal 0.947 0.758 – 1.18 0.63 93 587 exclusion phecode
732.1 Juvenile osteochondrosis Musculoskeletal 0.964 0.732 – 1.27 0.792 58 359 exclusion phecode
732.7 Osteochondritis dissecans Musculoskeletal 0.936 0.585 – 1.5 0.782 28 131 exclusion phecode
733 Other disorders of bone and cartilage Musculoskeletal 0.979 0.921 – 1.04 0.484 1511 4778 exclusion phecode
733.2 Cyst of bone Musculoskeletal 1.18 0.854 – 1.62 0.321 46 321 exclusion phecode
733.4 Aseptic necrosis of bone Musculoskeletal 0.857 0.71 – 1.04 0.11 124 847 exclusion phecode
733.6 Costochondritis Musculoskeletal 1.01 0.822 – 1.23 0.95 118 625 exclusion phecode
733.8 Malunion and nonunion of fracture Musculoskeletal 1.06 0.901 – 1.25 0.487 163 1288 exclusion phecode
733.9 Chondromalacia Musculoskeletal 1.48 0.869 – 2.51 0.15 16 133 exclusion phecode
735 Acquired foot deformities Musculoskeletal 0.985 0.928 – 1.05 0.621 1362 5729 exclusion phecode
735.1 Flat foot Musculoskeletal 1.1 0.955 – 1.26 0.191 257 1319 exclusion phecode
735.2 Acquired toe deformities Musculoskeletal 0.991 0.908 – 1.08 0.848 617 2701 exclusion phecode
735.21 Hammer toe (acquired) Musculoskeletal 0.988 0.889 – 1.1 0.823 433 1891 exclusion phecode
735.23 Hallux rigidus Musculoskeletal 0.938 0.781 – 1.13 0.494 134 818 exclusion phecode
735.3 Hallux valgus (Bunion) Musculoskeletal 0.878 0.801 – 0.963 0.00579 556 2948 exclusion phecode
736 Other acquired deformities of limbs Musculoskeletal 0.967 0.901 – 1.04 0.344 941 5091 exclusion phecode
736.1 Acquired deformities of forearm Musculoskeletal 0.629 0.407 – 0.971 0.0362 31 163 exclusion phecode
736.2 Acquired deformities of finger Musculoskeletal 1.01 0.78 – 1.3 0.959 71 415 exclusion phecode
736.3 Acquired deformities of hip Musculoskeletal 1.28 0.753 – 2.19 0.358 15 89 exclusion phecode
736.4 Genu valgum or varum (acquired) Musculoskeletal 0.905 0.725 – 1.13 0.381 93 559 exclusion phecode
736.5 Acquired deformities of knee Musculoskeletal 0.844 0.656 – 1.09 0.186 70 446 exclusion phecode
736.6 Unequal leg length (acquired) Musculoskeletal 0.92 0.747 – 1.13 0.432 110 592 exclusion phecode
737 Curvature of spine Musculoskeletal 0.967 0.873 – 1.07 0.518 439 2706 exclusion phecode
737.1 Kyphosis (acquired) Musculoskeletal 1.06 0.875 – 1.28 0.565 128 819 exclusion phecode
737.2 Lordosis (acquired) Musculoskeletal 1.06 0.616 – 1.81 0.839 17 120 exclusion phecode
737.3 Kyphoscoliosis and scoliosis Musculoskeletal 0.955 0.851 – 1.07 0.433 339 2030 exclusion phecode
738 Other acquired musculoskeletal deformity Musculoskeletal 0.988 0.905 – 1.08 0.792 574 4223 exclusion phecode
738.4 Acquired spondylolisthesis Musculoskeletal 0.938 0.827 – 1.06 0.312 291 1879 exclusion phecode
739 Contracture of joint Musculoskeletal 0.76 0.647 – 0.893 0.000842 185 1187 exclusion phecode
740 Osteoarthrosis Musculoskeletal 0.947 0.906 – 0.99 0.0158 4442 5120 exclusion phecode
740.1 Osteoarthritis; localized Musculoskeletal 0.935 0.886 – 0.986 0.0135 2371 4554 exclusion phecode
740.11 Osteoarthrosis, localized, primary Musculoskeletal 0.923 0.873 – 0.976 0.00486 2111 4391 exclusion phecode
740.12 Osteoarthrosis, localized, secondary Musculoskeletal 0.967 0.83 – 1.13 0.661 217 1170 exclusion phecode
740.2 Osteoarthrosis, generalized Musculoskeletal 0.943 0.86 – 1.03 0.218 659 2000 exclusion phecode
740.3
Osteoarthrosis involving more than one site
Osteoarthrosis involving more than one site, but not specified as generalized
 Musculoskeletal 0.91 0.757 – 1.09 0.317 150 524 exclusion phecode
740.9 Osteoarthrosis NOS Musculoskeletal 0.951 0.909 – 0.994 0.0266 4266 5093 exclusion phecode
741 Symptoms and disorders of the joints Musculoskeletal 0.961 0.918 – 1.01 0.0905 2781 6258 exclusion phecode
741.1 Ankylosis of joint Musculoskeletal 0.93 0.685 – 1.26 0.643 49 373 exclusion phecode
741.2 Stiffness of joint Musculoskeletal 0.97 0.867 – 1.09 0.602 362 2225 exclusion phecode
741.3 Difficulty in walking Musculoskeletal 0.971 0.905 – 1.04 0.421 964 4068 exclusion phecode
741.4 Joint effusions Musculoskeletal 0.983 0.915 – 1.06 0.648 983 4207 exclusion phecode
741.5 Hemarthrosis Musculoskeletal 0.988 0.706 – 1.38 0.945 46 189 exclusion phecode
741.6 Villonodular synovitis Musculoskeletal 0.953 0.579 – 1.57 0.849 22 113 exclusion phecode
742 Derangement of joint, non-traumatic Musculoskeletal 0.921 0.866 – 0.978 0.00755 1349 5821 exclusion phecode
742.1 Loose body in joint Musculoskeletal 1 0.698 – 1.44 0.995 35 227 exclusion phecode
742.2
Pathological, developmental or recurrent
Pathological, developmental or recurrent dislocation
 Musculoskeletal 0.943 0.719 – 1.24 0.672 60 393 exclusion phecode
742.8 Articular cartilage disorder Musculoskeletal 0.863 0.658 – 1.13 0.288 61 379 exclusion phecode
742.9 Other derangement of joint Musculoskeletal 0.918 0.862 – 0.977 0.00692 1273 5663 exclusion phecode
743
Osteoporosis, osteopenia and pathological
Osteoporosis, osteopenia and pathological fracture
 Musculoskeletal 0.999 0.953 – 1.05 0.969 2821 6655 exclusion phecode
743.1 Osteoporosis Musculoskeletal 1.02 0.953 – 1.1 0.521 1122 3538 exclusion phecode
743.11 Osteoporosis NOS Musculoskeletal 1.01 0.943 – 1.09 0.726 1103 3501 exclusion phecode
743.12 Senile osteoporosis Musculoskeletal 0.91 0.787 – 1.05 0.2 252 850 exclusion phecode
743.13 Other specified osteoporosis Musculoskeletal 0.962 0.791 – 1.17 0.703 120 521 exclusion phecode
743.2 Pathologic fracture Musculoskeletal 0.937 0.835 – 1.05 0.26 360 1770 exclusion phecode
743.21 Pathologic fracture of vertebrae Musculoskeletal 0.979 0.826 – 1.16 0.809 156 782 exclusion phecode
743.22 Pathologic fracture of femur Musculoskeletal 0.954 0.674 – 1.35 0.79 41 220 exclusion phecode
743.4 Stress fracture Musculoskeletal 0.926 0.787 – 1.09 0.35 170 847 exclusion phecode
743.9
Osteopenia or other disorder of bone and
Osteopenia or other disorder of bone and cartilage
 Musculoskeletal 0.993 0.944 – 1.04 0.774 2300 6345 exclusion phecode
745 Pain in joint Musculoskeletal 0.924 0.885 – 0.964 0.000247 6063 3607 exclusion phecode
747 Cardiac and circulatory congenital anomalies Congenital Anomalies 1 0.934 – 1.08 0.913 914 4487 exclusion phecode
747.1 Cardiac congenital anomalies Congenital Anomalies 1.01 0.936 – 1.1 0.752 776 3607 exclusion phecode
747.11 Cardiac shunt/ heart septal defect Congenital Anomalies 0.93 0.814 – 1.06 0.29 282 1284 exclusion phecode
747.12 Valvular heart disease/ heart chambers Congenital Anomalies 1.07 0.953 – 1.2 0.258 391 1587 exclusion phecode
747.13 Congenital anomalies of great vessels Congenital Anomalies 1.24 1.05 – 1.47 0.0109 175 850 exclusion phecode
747.2
Congenital anomalies of peripheral vascular
Congenital anomalies of peripheral vascular system
 Congenital Anomalies 1.05 0.887 – 1.25 0.557 155 956 exclusion phecode
748 Anomalies of respiratory system, congenital Congenital Anomalies 1.06 0.698 – 1.6 0.795 29 224 exclusion phecode
749 Congenital anomalies of face and neck Congenital Anomalies 0.994 0.818 – 1.21 0.952 114 972 exclusion phecode
749.1 Cleft palate Congenital Anomalies 1.19 0.552 – 2.58 0.654 6 122 exclusion phecode
749.2 Congenital anomalies of skull and face bones Congenital Anomalies 0.929 0.574 – 1.5 0.763 20 176 exclusion phecode
750 Digestive congenital anomalies Congenital Anomalies 0.978 0.863 – 1.11 0.728 275 1783 exclusion phecode
750.1 Upper gastrointestinal congenital anomalies Congenital Anomalies 1 0.792 – 1.27 0.986 70 682 exclusion phecode
750.11 Esophageal atresia/tracheoesophageal fistula Congenital Anomalies 0.79 0.552 – 1.13 0.198 30 231 exclusion phecode
750.13 Congenital anomalies of mouth/tongue Congenital Anomalies 0.867 0.499 – 1.51 0.611 15 147 exclusion phecode
750.14 Congenital anomalies of esophagus Congenital Anomalies 1.06 0.751 – 1.5 0.731 29 249 exclusion phecode
750.15 Congenital anomalies of stomach Congenital Anomalies 1.42 0.806 – 2.49 0.227 12 110 exclusion phecode
750.2 Lower gastrointestinal congenital anomalies Congenital Anomalies 0.997 0.861 – 1.15 0.969 204 1147 exclusion phecode
750.21 Congenital anomalies of intestine Congenital Anomalies 0.842 0.691 – 1.03 0.0866 110 655 exclusion phecode
750.22
Congenital anomaly of gallbladder, bile ducts
Congenital anomaly of gallbladder, bile ducts, liver, pancreas
 Congenital Anomalies 1.08 0.868 – 1.34 0.502 97 468 exclusion phecode
751 Genitourinary congenital anomalies Congenital Anomalies 0.932 0.857 – 1.01 0.105 646 3888 exclusion phecode
751.1 Congenital anomalies of genital organs Congenital Anomalies 0.964 0.818 – 1.14 0.661 163 1092 exclusion phecode
751.11 Congenital anomalies of female genital organs Congenital Anomalies 0.867 0.709 – 1.06 0.166 110 726 exclusion phecode
751.12 Congenital anomalies of male genital organs Congenital Anomalies 1.06 0.744 – 1.5 0.763 37 312 exclusion phecode
751.2 Congenital anomalies of urinary system Congenital Anomalies 0.933 0.845 – 1.03 0.175 486 2743 exclusion phecode
751.21 Cystic kidney disease Congenital Anomalies 0.919 0.82 – 1.03 0.147 377 1975 exclusion phecode
751.22 Other specified congenital anomalies of kidney Congenital Anomalies 0.854 0.677 – 1.08 0.182 84 584 exclusion phecode
751.3 Obstructive genitourinary defect Congenital Anomalies 1.02 0.725 – 1.43 0.921 35 335 exclusion phecode
752 Nervous system congenital anomalies Congenital Anomalies 0.933 0.822 – 1.06 0.285 275 2152 exclusion phecode
752.1 Neural tube defects Congenital Anomalies 0.911 0.791 – 1.05 0.195 222 1732 exclusion phecode
752.11 Spina bifida Congenital Anomalies 1.04 0.741 – 1.47 0.804 34 316 exclusion phecode
752.2
Other specified congenital anomalies of nervous
Other specified congenital anomalies of nervous system
 Congenital Anomalies 0.988 0.749 – 1.3 0.932 56 435 exclusion phecode
753 Congenital anomalies of the eye Congenital Anomalies 0.992 0.782 – 1.26 0.944 79 517 exclusion phecode
753.1 Congenital cataract and lens anomalies Congenital Anomalies 0.961 0.606 – 1.52 0.865 23 152 exclusion phecode
753.2 Congenital anomalies of posterior segment of eye Congenital Anomalies 1.16 0.754 – 1.78 0.504 22 142 exclusion phecode
754 Congenital musculoskeletal deformities of spine Congenital Anomalies 0.879 0.783 – 0.987 0.0295 339 2345 exclusion phecode
754.1 Lumbosacral spondylolysis, congenital Congenital Anomalies 1.05 0.764 – 1.45 0.756 52 280 exclusion phecode
754.2 Spondylolisthesis, congenital Congenital Anomalies 0.889 0.746 – 1.06 0.19 148 1069 exclusion phecode
755 Congenital anomalies of limbs Congenital Anomalies 0.927 0.805 – 1.07 0.294 218 1518 exclusion phecode
755.1 Congenital deformities of feet Congenital Anomalies 0.92 0.753 – 1.12 0.412 113 775 exclusion phecode
755.4
Congenital anomalies of upper limb, including
Congenital anomalies of upper limb, including shoulder girdle
 Congenital Anomalies 0.96 0.554 – 1.66 0.885 18 140 exclusion phecode
755.6
Other congenital anomalies of lower limb
Other congenital anomalies of lower limb, including pelvic girdle
 Congenital Anomalies 0.909 0.732 – 1.13 0.391 88 579 exclusion phecode
755.61 Congenital hip dysplasia and deformity Congenital Anomalies 1 0.749 – 1.35 0.979 47 350 exclusion phecode
756 Other congenital musculoskeletal anomalies Congenital Anomalies 0.907 0.814 – 1.01 0.0785 371 2554 exclusion phecode
756.1 Congenital anomalies of abdominal wall; diaphram Congenital Anomalies 0.831 0.472 – 1.46 0.519 16 116 exclusion phecode
756.2
Pectus and other congenital anomalies of
Pectus and other congenital anomalies of ribs/sternum
 Congenital Anomalies 0.842 0.501 – 1.41 0.516 19 103 exclusion phecode
756.3
Congenital anomalies of muscle, tendon, fascia
Congenital anomalies of muscle, tendon, fascia, and connective tissue
 Congenital Anomalies 0.924 0.748 – 1.14 0.461 94 578 exclusion phecode
756.5 Congenital osteodystrophies Congenital Anomalies 0.956 0.844 – 1.08 0.474 274 1977 exclusion phecode
757 Congenital anomalies of the integument Congenital Anomalies 1.04 0.853 – 1.28 0.68 106 848 exclusion phecode
758 Chromosomal anomalies and genetic disorders Congenital Anomalies 0.971 0.747 – 1.26 0.826 69 396 exclusion phecode
758.1 Chromosomal anomalies Congenital Anomalies 0.999 0.727 – 1.37 0.996 48 298 exclusion phecode
759 Other and unspecified congenital anomalies Congenital Anomalies 1.05 0.884 – 1.24 0.605 158 1067 exclusion phecode
759.1 Anomalies of endocrine glands, congenital Congenital Anomalies 1.11 0.689 – 1.79 0.666 17 150 exclusion phecode
760 Back pain Symptoms 0.948 0.91 – 0.988 0.0115 5007 4666 exclusion phecode
761 Cervicalgia Symptoms 0.955 0.91 – 1 0.0639 2209 7376 exclusion phecode
763
Thoracic or lumbosacral neuritis or
Thoracic or lumbosacral neuritis or radiculitis, unspecified
 Symptoms 0.959 0.901 – 1.02 0.183 1244 5925 exclusion phecode
764 Sciatica Symptoms 0.97 0.912 – 1.03 0.34 1268 5947 exclusion phecode
765 Cervical radiculitis Symptoms 0.973 0.89 – 1.06 0.552 588 3387 exclusion phecode
766 Neuralgia, neuritis, and radiculitis NOS Symptoms 0.958 0.907 – 1.01 0.125 1611 6710 exclusion phecode
767 Cervicocranial/Cervicobrachial syndrome Symptoms 1.12 0.805 – 1.56 0.499 47 255 exclusion phecode
769 Nonallopathic lesions NEC Symptoms 0.949 0.851 – 1.06 0.352 395 2398 exclusion phecode
770 Myalgia and myositis unspecified Symptoms 0.978 0.927 – 1.03 0.426 1692 6734 exclusion phecode
771 Musculoskeletal symptoms referable to limbs Symptoms 0.964 0.911 – 1.02 0.199 1606 5965 exclusion phecode
771.1 Swelling of limb Symptoms 0.977 0.929 – 1.03 0.365 2219 6003 exclusion phecode
771.2 Cramp of limb Symptoms 0.906 0.815 – 1.01 0.0694 430 2058 exclusion phecode
772 Symptoms of the muscles Symptoms 0.967 0.892 – 1.05 0.421 718 3865 exclusion phecode
772.1 Muscular wasting and disuse atrophy Symptoms 1.02 0.844 – 1.24 0.804 126 756 exclusion phecode
772.2 Spasm of muscle Symptoms 0.96 0.887 – 1.04 0.309 740 4223 exclusion phecode
772.3 Muscle weakness Symptoms 1.02 0.949 – 1.09 0.66 1081 5232 exclusion phecode
772.4 Rhabdomyolysis Symptoms 1.09 0.83 – 1.42 0.551 66 314 exclusion phecode
772.6 Facial weakness Symptoms 0.884 0.755 – 1.03 0.125 196 939 exclusion phecode
780 Hypothermia/Chills Symptoms 1.05 0.897 – 1.22 0.565 200 1050 exclusion phecode
781
Symptoms involving nervous and musculoskeletal
Symptoms involving nervous and musculoskeletal systems
 Symptoms 0.974 0.912 – 1.04 0.425 1127 5294 exclusion phecode
781.1 Loss of height Symptoms 0.859 0.658 – 1.12 0.267 61 298 exclusion phecode
781.2 Abnormal posture Symptoms 0.853 0.534 – 1.36 0.507 24 121 exclusion phecode
782.3 Edema Symptoms 1.02 0.971 – 1.07 0.436 2356 6474 exclusion phecode
782.6 Pallor and flushing Symptoms 0.94 0.823 – 1.07 0.362 265 1624 exclusion phecode
783 Fever of unknown origin Symptoms 1.04 0.993 – 1.1 0.09 2137 7433 exclusion phecode
783.1 Postprocedural fever Symptoms 1.03 0.818 – 1.29 0.826 85 523 exclusion phecode
785 Abdominal pain Symptoms 0.991 0.951 – 1.03 0.665 5240 4431 exclusion phecode
788 Syncope and collapse Symptoms 1.04 0.981 – 1.1 0.194 1525 6931 exclusion phecode
789 Nausea and vomiting Symptoms 1.05 1.01 – 1.1 0.0275 3148 6487 exclusion phecode
789.1 Persistent vomiting Symptoms 1.05 0.924 – 1.2 0.437 271 1389 exclusion phecode
790 Nonspecific findings on examination of blood Symptoms 1.03 0.958 – 1.1 0.461 1067 3880 exclusion phecode
790.1 Elevated sedimentation rate Symptoms 1.01 0.808 – 1.27 0.911 94 413 exclusion phecode
790.6 Other abnormal blood chemistry Symptoms 1.03 0.987 – 1.08 0.164 3143 6106 exclusion phecode
790.8 Elevated C-reactive protein (CRP) Symptoms 0.973 0.79 – 1.2 0.795 112 499 exclusion phecode
790.9 Abnormal arterial blood gases Symptoms 1.05 0.793 – 1.38 0.751 62 263 exclusion phecode
791 Gangrene Symptoms 1.07 0.892 – 1.28 0.469 153 748 exclusion phecode
792
Abnormal Papanicolaou smear of cervix and
Abnormal Papanicolaou smear of cervix and cervical HPV
 Genitourinary 0.942 0.868 – 1.02 0.157 815 2438 exclusion phecode
792.1
Papanicolaou smear of cervix or vagina with
Papanicolaou smear of cervix or vagina with atypical squamous cells
 Genitourinary 1.01 0.888 – 1.14 0.936 344 1547 exclusion phecode
794
Abnormal results of other function studies
Abnormal results of other function studies (bladder, pancreas, placenta, spleen, etc)
 Symptoms 1.01 0.818 – 1.24 0.958 106 1006 exclusion phecode
795
Other and nonspecific abnormal cytological
Other and nonspecific abnormal cytological, histological and immunological findings
 Symptoms 1.06 0.968 – 1.15 0.217 606 3797 exclusion phecode
795.8 Abnormal tumor markers Symptoms 0.961 0.87 – 1.06 0.427 458 3468 exclusion phecode
795.81 Elevated carcinoembryonic antigen [CEA] Symptoms 1.09 0.661 – 1.79 0.74 15 131 exclusion phecode
795.82 Elevated cancer antigen 125 [CA 125] Symptoms 0.861 0.609 – 1.22 0.394 37 339 exclusion phecode
796 Elevated prostate specific antigen [PSA] Genitourinary 0.935 0.85 – 1.03 0.163 616 2005 exclusion phecode
797 Shock Symptoms 1.05 0.927 – 1.19 0.441 301 1358 exclusion phecode
797.1 Cardiogenic shock Symptoms 1.05 0.875 – 1.26 0.598 156 599 exclusion phecode
798 Malaise and fatigue Symptoms 1.03 0.992 – 1.08 0.111 4173 5496 exclusion phecode
798.1 Chronic fatigue syndrome Symptoms 1.03 0.949 – 1.12 0.458 700 2949 exclusion phecode
800 Fracture of lower limb Injuries & Poisonings 0.948 0.874 – 1.03 0.195 694 4223 exclusion phecode
800.1 Fracture of neck of femur Injuries & Poisonings 0.921 0.784 – 1.08 0.316 178 962 exclusion phecode
800.2 Fracture of unspecified part of femur Injuries & Poisonings 0.974 0.835 – 1.14 0.737 196 1206 exclusion phecode
800.3 Fracture of tibia and fibula Injuries & Poisonings 1.01 0.886 – 1.16 0.858 252 1568 exclusion phecode
800.4 Fracture of patella Injuries & Poisonings 0.932 0.764 – 1.14 0.483 113 622 exclusion phecode
801 Fracture of ankle and foot Injuries & Poisonings 0.956 0.888 – 1.03 0.237 861 4449 exclusion phecode
801.1 Fracture of foot Injuries & Poisonings 0.975 0.87 – 1.09 0.665 339 2087 exclusion phecode
802 Fracture of pelvis Injuries & Poisonings 1.05 0.853 – 1.3 0.638 102 648 exclusion phecode
803 Fracture of upper limb Injuries & Poisonings 0.888 0.814 – 0.968 0.0071 594 3705 exclusion phecode
803.1 Fracture of humerus Injuries & Poisonings 0.96 0.829 – 1.11 0.582 213 1283 exclusion phecode
803.2 Fracture of radius and ulna Injuries & Poisonings 0.877 0.781 – 0.984 0.0249 334 2042 exclusion phecode
803.21 Colles' fracture Injuries & Poisonings 0.731 0.583 – 0.916 0.00651 87 520 exclusion phecode
803.3 Fracture of clavicle or scapula Injuries & Poisonings 0.875 0.728 – 1.05 0.154 134 903 exclusion phecode
804 Fracture of hand or wrist Injuries & Poisonings 0.915 0.831 – 1.01 0.0669 516 3008 exclusion phecode
805
Fracture of vertebral column without mention of
Fracture of vertebral column without mention of spinal cord injury
 Injuries & Poisonings 1.04 0.932 – 1.16 0.496 398 2379 exclusion phecode
807 Fracture of ribs Injuries & Poisonings 1.02 0.896 – 1.17 0.746 262 1352 exclusion phecode
809 Fracture of unspecified bones Injuries & Poisonings 0.932 0.866 – 1 0.0629 839 5265 exclusion phecode
816 Cerebral laceration and contusion Injuries & Poisonings 0.875 0.528 – 1.45 0.604 17 109 exclusion phecode
817 Concussion Injuries & Poisonings 1.01 0.899 – 1.14 0.859 353 2066 exclusion phecode
818 Intracranial hemorrhage (injury) Injuries & Poisonings 0.869 0.718 – 1.05 0.148 119 728 exclusion phecode
818.1 Subdural hemorrhage (injury) Injuries & Poisonings 0.701 0.488 – 1.01 0.0544 32 199 exclusion phecode
818.2 Subarachnoid hemorrhage (injury) Injuries & Poisonings 1.09 0.744 – 1.61 0.649 32 244 exclusion phecode
819
Skull and face fracture and other intercranial
Skull and face fracture and other intercranial injury
 Injuries & Poisonings 1.02 0.938 – 1.11 0.659 671 4482 exclusion phecode
830 Dislocation Injuries & Poisonings 0.981 0.92 – 1.05 0.567 1115 6642 exclusion phecode
835 Internal derangement of knee Injuries & Poisonings 0.946 0.872 – 1.03 0.18 711 4300 exclusion phecode
836 Traumatic arthropathy Injuries & Poisonings 0.897 0.748 – 1.08 0.24 148 908 exclusion phecode
840 Sprains and strains Injuries & Poisonings 0.93 0.888 – 0.974 0.00211 2569 6735 exclusion phecode
840.1 Muscle/tendon sprain Injuries & Poisonings 0.882 0.754 – 1.03 0.12 199 985 exclusion phecode
840.2 Rotator cuff (capsule) sprain Injuries & Poisonings 0.889 0.813 – 0.973 0.0106 574 3052 exclusion phecode
840.3 Joint/ligament sprain Injuries & Poisonings 0.872 0.809 – 0.94 0.00033 858 4465 exclusion phecode
841 Sprains and strains of back and neck Injuries & Poisonings 0.825 0.756 – 0.901 1.81e-05 647 3056 exclusion phecode
842 Other sprains and strains Injuries & Poisonings 0.934 0.847 – 1.03 0.166 499 2574 exclusion phecode
850 Hemorrhage or hematoma complicating a procedure Injuries & Poisonings 1.05 0.965 – 1.14 0.257 648 3586 exclusion phecode
851
Complications of transplants and reattached
Complications of transplants and reattached limbs
 Injuries & Poisonings 1.06 0.992 – 1.13 0.0846 1087 4834 exclusion phecode
853 Complication of colostomy or enterostomy Injuries & Poisonings 1.13 0.936 – 1.37 0.199 132 681 exclusion phecode
854
Complications of cardiac/vascular device
Complications of cardiac/vascular device, implant, and graft
 Injuries & Poisonings 1.14 1.06 – 1.23 0.000517 895 3683 exclusion phecode
855
Complication of nervous system device, implant
Complication of nervous system device, implant, and graft
 Injuries & Poisonings 1.51 1.09 – 2.1 0.0129 47 417 exclusion phecode
856
Vascular complications of surgery and medical
Vascular complications of surgery and medical procedures
 Injuries & Poisonings 1.21 0.979 – 1.49 0.0777 121 513 exclusion phecode
857
Mechanical complication of unspecified
Mechanical complication of unspecified genitourinary device, implant, and graft
 Injuries & Poisonings 1.03 0.916 – 1.15 0.648 359 2342 exclusion phecode
858 Complication of internal orthopedic device Injuries & Poisonings 1.05 0.945 – 1.16 0.389 442 3458 exclusion phecode
859
Complication due to other implant and internal
Complication due to other implant and internal device
 Injuries & Poisonings 1.09 0.996 – 1.2 0.0602 532 3638 exclusion phecode
860 Bone marrow or stem cell transplant Neoplasms 0.956 0.737 – 1.24 0.732 68 403 exclusion phecode
870 Open wounds of head; neck; and trunk Injuries & Poisonings 1.04 0.976 – 1.1 0.233 1258 6694 exclusion phecode
870.1 Open wound or laceration of eye or eyelid Injuries & Poisonings 1.19 0.916 – 1.54 0.193 64 432 exclusion phecode
870.2 Open wound of ear Injuries & Poisonings 1 0.729 – 1.38 0.987 45 251 exclusion phecode
870.3 Other open wound of head and face Injuries & Poisonings 0.907 0.813 – 1.01 0.0778 385 2549 exclusion phecode
870.4 Open wound of nose and sinus Injuries & Poisonings 0.789 0.577 – 1.08 0.14 41 368 exclusion phecode
870.5 Open wound of lip and mouth Injuries & Poisonings 0.994 0.751 – 1.32 0.969 58 482 exclusion phecode
870.6 Open wound of neck Injuries & Poisonings 0.706 0.484 – 1.03 0.072 33 362 exclusion phecode
870.8 Open wound of genital organs Injuries & Poisonings 1.43 0.964 – 2.11 0.0758 28 267 exclusion phecode
871 Open wounds of extremities Injuries & Poisonings 0.985 0.927 – 1.05 0.634 1288 6257 exclusion phecode
871.1 Open wound of hand except finger(s) Injuries & Poisonings 1.03 0.874 – 1.2 0.751 190 1106 exclusion phecode
871.2 Open wound of finger(s) Injuries & Poisonings 0.989 0.884 – 1.11 0.853 369 2169 exclusion phecode
871.3 Open wound of foot except toe(s) alone Injuries & Poisonings 1.03 0.894 – 1.18 0.718 253 1255 exclusion phecode
871.4 Open wound of toe(s) Injuries & Poisonings 1.02 0.862 – 1.21 0.812 171 860 exclusion phecode
872 Traumatic amputation Injuries & Poisonings 0.994 0.86 – 1.15 0.93 230 1228 exclusion phecode
874 Complication of amputation stump Injuries & Poisonings 0.871 0.679 – 1.12 0.277 83 384 exclusion phecode
875 Non-healing surgical wound Injuries & Poisonings 0.948 0.794 – 1.13 0.549 164 1017 exclusion phecode
876
Posttraumatic wound infection not elsewhere
Posttraumatic wound infection not elsewhere classified
 Injuries & Poisonings 1.07 0.943 – 1.21 0.301 287 1574 exclusion phecode
907 Injuries to the nervous system Injuries & Poisonings 0.949 0.824 – 1.09 0.474 219 1928 exclusion phecode
910 Superficial injury, infected Injuries & Poisonings 1.19 0.898 – 1.59 0.223 61 271 exclusion phecode
911 Blister Injuries & Poisonings 0.913 0.773 – 1.08 0.279 170 927 exclusion phecode
912 Insect bite Injuries & Poisonings 0.812 0.699 – 0.945 0.00706 205 1157 exclusion phecode
913 Toxic effect of venom Injuries & Poisonings 0.831 0.69 – 1 0.0505 144 743 exclusion phecode
916 Contusion Injuries & Poisonings 0.965 0.915 – 1.02 0.191 1729 7132 exclusion phecode
930 Allergic reaction to food Injuries & Poisonings 0.88 0.771 – 1 0.0588 279 1161 exclusion phecode
931
Contact dermatitis and other eczema due to
Contact dermatitis and other eczema due to plants [except food]
 Dermatologic 0.825 0.717 – 0.948 0.0069 239 1217 exclusion phecode
938 Dermatitis due to solar radiation Dermatologic 0.955 0.905 – 1.01 0.0928 2085 4391 exclusion phecode
938.1 Acute dermatitis due to solar radiation Dermatologic 0.807 0.629 – 1.04 0.0929 80 329 exclusion phecode
938.2 Chronic dermatitis due to solar radiation Dermatologic 0.955 0.905 – 1.01 0.102 2009 4330 exclusion phecode
939
Atopic/contact dermatitis due to other or
Atopic/contact dermatitis due to other or unspecified
 Dermatologic 0.973 0.926 – 1.02 0.281 2549 4785 exclusion phecode
939.1 Contact and allergic dermatitis of eyelid Dermatologic 1.04 0.718 – 1.51 0.833 35 159 exclusion phecode
941 Adverse reaction to serum or vaccine Injuries & Poisonings 1.23 0.939 – 1.6 0.134 75 324 exclusion phecode
942 Infusion and transfusion reaction Injuries & Poisonings 1.11 0.892 – 1.38 0.353 114 425 exclusion phecode
946 Anaphylactic shock NOS Injuries & Poisonings 0.833 0.71 – 0.978 0.0255 195 874 exclusion phecode
947 Urticaria Dermatologic 0.945 0.846 – 1.05 0.312 401 1826 exclusion phecode
949 Allergies, other Injuries & Poisonings 0.974 0.926 – 1.02 0.306 2455 4784 exclusion phecode
952
Spinal cord injury without evidence of spinal
Spinal cord injury without evidence of spinal bone injury
 Injuries & Poisonings 0.988 0.808 – 1.21 0.904 114 973 exclusion phecode
957 Injury to other and unspecified nerves Injuries & Poisonings 0.607 0.393 – 0.94 0.0251 25 242 exclusion phecode
958
Certain early complications of trauma or
Certain early complications of trauma or procedure
 Injuries & Poisonings 1.05 0.937 – 1.17 0.421 369 2396 exclusion phecode
958.1 Postoperative shock Injuries & Poisonings 1.15 0.883 – 1.51 0.294 74 339 exclusion phecode
958.2 Traumatic and surgical subcutaneous emphysema Injuries & Poisonings 1.17 0.784 – 1.74 0.445 28 239 exclusion phecode
960 Poisoning by antibiotics Injuries & Poisonings 0.996 0.921 – 1.08 0.927 776 3940 exclusion phecode
960.1
Adverse effects of antibacterials (not
Adverse effects of antibacterials (not penicillins)
 Injuries & Poisonings 1.01 0.845 – 1.21 0.914 143 692 exclusion phecode
960.2 Allergy/adverse effect of penicillin Injuries & Poisonings 1.02 0.926 – 1.12 0.682 490 2760 exclusion phecode
961 Poisoning by other anti-infectives Injuries & Poisonings 1.03 0.88 – 1.21 0.694 196 913 exclusion phecode
961.1 Poisoning/allergy of sulfonamides Injuries & Poisonings 0.973 0.864 – 1.1 0.657 320 1810 exclusion phecode
962 Poisoning by hormones and synthetic substitutes Injuries & Poisonings 1.02 0.905 – 1.14 0.786 358 1711 exclusion phecode
962.1
Adrenal cortical steroids causing adverse
Adrenal cortical steroids causing adverse effects in therapeutic use
 Injuries & Poisonings 0.974 0.821 – 1.15 0.759 178 770 exclusion phecode
962.2
Insulins and antidiabetic agents causing
Insulins and antidiabetic agents causing adverse effects in therapeutic use
 Injuries & Poisonings 0.991 0.707 – 1.39 0.956 41 226 exclusion phecode
962.3
Hormones and synthetic substitutes causing
Hormones and synthetic substitutes causing adverse effects in therapeutic use
 Injuries & Poisonings 1.15 0.985 – 1.35 0.0774 194 1032 exclusion phecode
963 Poisoning by primarily systemic agents Injuries & Poisonings 1.03 0.947 – 1.11 0.533 728 4057 exclusion phecode
963.1
Antineoplastic and immunosuppressive drugs
Antineoplastic and immunosuppressive drugs causing adverse effects
 Injuries & Poisonings 1.05 0.964 – 1.14 0.276 702 3964 exclusion phecode
964
Poisoning by agents primarily affecting blood
Poisoning by agents primarily affecting blood constituents
 Injuries & Poisonings 1.02 0.914 – 1.15 0.688 379 1547 exclusion phecode
964.1 Anticoagulants causing adverse effects Injuries & Poisonings 0.999 0.89 – 1.12 0.987 362 1482 exclusion phecode
965
Poisoning by analgesics, antipyretics, and
Poisoning by analgesics, antipyretics, and antirheumatics
 Injuries & Poisonings 1.11 0.976 – 1.26 0.114 297 1465 exclusion phecode
965.1
Opiates and related narcotics causing adverse
Opiates and related narcotics causing adverse effects in therapeutic use
 Injuries & Poisonings 1.06 0.956 – 1.18 0.267 454 2386 exclusion phecode
965.3
Salicylates causing adverse effects in
Salicylates causing adverse effects in therapeutic use
 Injuries & Poisonings 0.923 0.656 – 1.3 0.647 33 207 exclusion phecode
966
Poisoning by anticonvulsants and
Poisoning by anticonvulsants and anti-Parkinsonism drugs
 Injuries & Poisonings 0.737 0.509 – 1.07 0.105 29 187 exclusion phecode
967
Adverse effects of sedatives or other central
Adverse effects of sedatives or other central nervous system depressants and anesthetics
 Injuries & Poisonings 0.972 0.865 – 1.09 0.635 328 2129 exclusion phecode
969 Poisoning by psychotropic agents Injuries & Poisonings 1.1 0.881 – 1.38 0.39 110 471 exclusion phecode
971
Poisoning by drugs primarily affecting the
Poisoning by drugs primarily affecting the autonomic nervous system
 Injuries & Poisonings 0.717 0.467 – 1.1 0.127 37 162 exclusion phecode
972
Poisoning by agents primarily affecting the
Poisoning by agents primarily affecting the cardiovascular system
 Injuries & Poisonings 0.952 0.796 – 1.14 0.588 157 615 exclusion phecode
972.1
Cardiac rhythm regulators causing adverse
Cardiac rhythm regulators causing adverse effects in therapeutic use
 Injuries & Poisonings 0.901 0.635 – 1.28 0.558 46 166 exclusion phecode
972.6 Antihypertensive agents causing adverse effects Injuries & Poisonings 1.03 0.776 – 1.37 0.836 67 219 exclusion phecode
974
Poisoning by water, mineral, and uric acid
Poisoning by water, mineral, and uric acid metabolism drugs
 Injuries & Poisonings 0.978 0.735 – 1.3 0.88 68 275 exclusion phecode
975
Poisoning by agents primarily acting on the
Poisoning by agents primarily acting on the smooth and skeletal muscles and respiratory system
 Injuries & Poisonings 0.804 0.54 – 1.2 0.284 32 135 exclusion phecode
976
Poisoning by agents primarily affecting skin &
Poisoning by agents primarily affecting skin & mucous membrane, ophthalmological, otorhinolaryngological, & dental drugs
 Injuries & Poisonings 1.07 0.745 – 1.54 0.71 30 138 exclusion phecode
977 Personal history of allergy to medicinal agents Injuries & Poisonings 0.996 0.911 – 1.09 0.935 615 2916 exclusion phecode
979 Adverse drug events and drug allergies Injuries & Poisonings 1.02 0.955 – 1.08 0.609 1234 5603 exclusion phecode
980
Encounter for long-term (current) use of
Encounter for long-term (current) use of antibiotics
 Infectious Diseases 1.01 0.914 – 1.12 0.822 422 3000 exclusion phecode
985 Toxic effect of other metals Injuries & Poisonings 1.21 0.722 – 2.02 0.471 19 129 exclusion phecode
989
Toxic effect of other substances, chiefly
Toxic effect of other substances, chiefly nonmedicinal as to source
 Injuries & Poisonings 0.874 0.646 – 1.18 0.383 48 333 exclusion phecode
990 Effects radiation NOS Injuries & Poisonings 1.03 0.955 – 1.11 0.436 755 5841 exclusion phecode
994 Sepsis and SIRS Injuries & Poisonings 1.06 0.982 – 1.13 0.141 883 4532 exclusion phecode
994.1 Systemic inflammatory response syndrome (SIRS) Injuries & Poisonings 1.1 0.908 – 1.34 0.324 120 633 exclusion phecode
994.2 Sepsis Injuries & Poisonings 1.05 0.973 – 1.13 0.216 849 4334 exclusion phecode
994.21 Septic shock Injuries & Poisonings 1.09 0.964 – 1.24 0.166 295 1278 exclusion phecode
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