Departments of Anesthesiology and Biostatistics | University of Michigan

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Scores Direct LDL cholesterol (IRNT) Michigan Genomics Initiative Freeze 3 (MGI) PheWAS analysis

Direct LDL cholesterol (IRNT) — Michigan Genomics Initiative Freeze 3 (MGI) PRS PheWAS

PRS model
PRS ID exprsweb-ldl-30780-irnt-plink-mgi-freeze3-20211120Legacy PLINKC+T (GT)UK Biobank GWAS

Evaluation cohort: Michigan Genomics Initiative Freeze 3 (MGI).

This page pairs the PheWAS plot with the full sortable table for the all-subject and exclusion scans.

Read the all-subject and exclusion scans separately. The combined view is only a browsing aid, and the selected-phecode panel below is only meaningful when the same phecode exists in both scans.

ExPRS exclusion definition

Exclusion cohort: normal-range subset (0.01-100).

For this ExPRS, the exclusion sensitivity scan keeps only the study's normal-range subset for Direct LDL cholesterol (IRNT) (0.01-100) before rerunning the PheWAS. This is an exposure-based sensitivity analysis rather than a diagnosis-based exclusion.

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Signal overview

The plot gives a quick view of the currently visible associations. Click a point to pin its details, inspect that phecode across scans when both rows exist, or open the matching phecode detail page.

142 rows visible 16 categories
Phecode Description Category OR 95% CI P value Cases Controls Analysis Link
008 Intestinal infection Infectious Diseases 0.991 0.954 – 1.03 0.643 3004 29292 all phecode
008.5 Bacterial enteritis Infectious Diseases 0.999 0.943 – 1.06 0.963 1322 13162 all phecode
008.52 Intestinal infection due to C. difficile Infectious Diseases 1.02 0.956 – 1.09 0.569 1046 10455 all phecode
008.6 Viral Enteritis Infectious Diseases 0.996 0.925 – 1.07 0.912 770 7676 all phecode
010 Tuberculosis Infectious Diseases 0.99 0.87 – 1.13 0.88 244 2425 all phecode
031 Diseases due to other mycobacteria Infectious Diseases 0.916 0.739 – 1.13 0.421 86 855 all phecode
038 Septicemia Infectious Diseases 1.01 0.974 – 1.06 0.486 2582 24779 all phecode
038.1 Gram negative septicemia Infectious Diseases 0.99 0.908 – 1.08 0.811 568 5629 all phecode
038.2 Gram positive septicemia Infectious Diseases 0.999 0.873 – 1.14 0.994 235 2350 all phecode
038.3 Bacteremia Infectious Diseases 0.997 0.94 – 1.06 0.928 1210 12079 all phecode
041 Bacterial infection NOS Infectious Diseases 0.995 0.967 – 1.02 0.711 5750 38799 all phecode
041.1 Staphylococcus infections Infectious Diseases 0.961 0.915 – 1.01 0.117 1707 16977 all phecode
041.11 Methicillin sensitive Staphylococcus aureus Infectious Diseases 0.939 0.878 – 1 0.0692 920 9192 all phecode
041.12 Methicillin resistant Staphylococcus aureus Infectious Diseases 0.974 0.905 – 1.05 0.489 783 7812 all phecode
041.2 Streptococcus infection Infectious Diseases 0.979 0.931 – 1.03 0.417 1632 16287 all phecode
041.21 Rheumatic fever / chorea Infectious Diseases 0.997 0.878 – 1.13 0.966 257 2554 all phecode
041.4 E. coli Infectious Diseases 1.03 0.966 – 1.09 0.406 1175 11680 all phecode
041.8 H. pylori Infectious Diseases 1.01 0.885 – 1.15 0.909 257 2521 all phecode
041.9 Infection with drug-resistant microorganisms Infectious Diseases 1.06 0.958 – 1.18 0.245 387 3864 all phecode
053 Herpes zoster Infectious Diseases 0.999 0.948 – 1.05 0.982 1560 15184 all phecode
053.1 Herpes zoster with nervous system complications Infectious Diseases 0.885 0.77 – 1.02 0.0875 220 2169 all phecode
054 Herpes simplex Infectious Diseases 0.987 0.937 – 1.04 0.624 1593 15600 all phecode
070 Viral hepatitis Infectious Diseases 0.995 0.927 – 1.07 0.888 829 8280 all phecode
070.1 Viral hepatitis A Infectious Diseases 0.942 0.757 – 1.17 0.595 87 860 all phecode
070.2 Viral hepatitis B Infectious Diseases 0.951 0.827 – 1.09 0.475 215 2138 all phecode
070.3 Viral hepatitis C Infectious Diseases 0.982 0.898 – 1.07 0.681 528 5280 all phecode
070.4 Chronic hepatitis Infectious Diseases 1.05 0.908 – 1.22 0.495 197 1964 all phecode
070.9 Hepatitis NOS Infectious Diseases 1 0.946 – 1.07 0.873 1145 11381 all phecode
071 Human immunodeficiency virus [HIV] disease Infectious Diseases 1.25 1.05 – 1.49 0.0122 145 1450 all phecode
071.1 HIV infection, symptomatic Infectious Diseases 1.38 1.13 – 1.68 0.00185 117 1163 all phecode
078 Viral warts & HPV Infectious Diseases 1 0.97 – 1.04 0.793 3434 29624 all phecode
079 Viral infection Infectious Diseases 1.03 1 – 1.06 0.0316 6664 35342 all phecode
079.1 Varicella infection Infectious Diseases 1.02 0.984 – 1.05 0.291 3793 31251 all phecode
079.2 Infectious mononucleosis Infectious Diseases 1.13 1 – 1.29 0.0503 283 2723 all phecode
079.9 Viremia, NOS Infectious Diseases 1.04 0.966 – 1.12 0.307 838 8253 all phecode
080 Postoperative infection Infectious Diseases 0.98 0.942 – 1.02 0.329 2619 26065 all phecode
081
Infection/inflammation of internal prosthetic
Infection/inflammation of internal prosthetic device; implant; and graft
 Infectious Diseases 0.958 0.91 – 1.01 0.103 1589 15884 all phecode
090
Sexually transmitted infections (not HIV or
Sexually transmitted infections (not HIV or hepatitis)
 Infectious Diseases 1.08 1.01 – 1.15 0.0292 965 9630 all phecode
110 Dermatophytosis / Dermatomycosis Infectious Diseases 0.981 0.947 – 1.02 0.285 3544 30054 all phecode
110.1 Dermatophytosis Infectious Diseases 0.983 0.947 – 1.02 0.352 3241 27244 all phecode
110.11 Dermatophytosis of nail Infectious Diseases 0.99 0.945 – 1.04 0.67 2044 16765 all phecode
110.12 Althete's foot Infectious Diseases 1.01 0.941 – 1.08 0.815 899 8043 all phecode
110.13 Dermatophytosis of the body Infectious Diseases 1.01 0.938 – 1.09 0.797 790 7827 all phecode
110.2 Dermatomycoses Infectious Diseases 0.929 0.838 – 1.03 0.157 398 3971 all phecode
112 Candidiasis Infectious Diseases 0.993 0.96 – 1.03 0.692 3685 30495 all phecode
112.3 Candidiasis of skin and nails Infectious Diseases 1.01 0.934 – 1.09 0.802 682 6732 all phecode
117 Mycoses Infectious Diseases 1.01 0.929 – 1.1 0.82 608 6069 all phecode
117.1 Histoplasmosis Infectious Diseases 1.04 0.834 – 1.31 0.707 81 801 all phecode
117.4 Aspergillosis Infectious Diseases 1.12 0.938 – 1.33 0.216 140 1387 all phecode
130 Spirochetal infection Infectious Diseases 1.01 0.862 – 1.18 0.917 168 1677 all phecode
130.1 Lyme disease Infectious Diseases 1.07 0.888 – 1.29 0.479 116 1160 all phecode
131 Protozoan infection Infectious Diseases 0.97 0.75 – 1.25 0.815 61 610 all phecode
132 Infestation (lice, mites) Infectious Diseases 0.883 0.762 – 1.02 0.0979 195 1948 all phecode
134 Helminthiases Infectious Diseases 0.887 0.712 – 1.11 0.288 83 812 all phecode
134.1 Intestinal helminthiases Infectious Diseases 0.886 0.672 – 1.17 0.391 53 513 all phecode
136 Other infectious and parasitic diseases Infectious Diseases 0.99 0.955 – 1.03 0.586 3279 32486 all phecode
145 Cancer of mouth Neoplasms 0.963 0.913 – 1.02 0.163 1481 14725 all phecode
145.1 Cancer of lip Neoplasms 0.827 0.662 – 1.03 0.0947 76 750 all phecode
145.2 Cancer of tongue Neoplasms 0.948 0.875 – 1.03 0.194 645 6430 all phecode
145.3 Cancer of major salivary glands Neoplasms 1 0.9 – 1.12 0.956 361 3597 all phecode
145.4 Cancer of the gums Neoplasms 0.921 0.789 – 1.07 0.296 166 1632 all phecode
145.5 Cancer of the mouth floor Neoplasms 0.982 0.854 – 1.13 0.801 206 2048 all phecode
149 Cancer of larynx, pharynx, nasal cavities Neoplasms 0.968 0.915 – 1.02 0.266 1290 12873 all phecode
149.1 Cancer of oropharynx Neoplasms 1.02 0.914 – 1.13 0.748 350 3499 all phecode
149.2 Cancer of nasopharynx Neoplasms 0.878 0.72 – 1.07 0.198 100 1000 all phecode
149.3 Cancer of hypopharynx Neoplasms 1.18 0.942 – 1.48 0.148 82 819 all phecode
149.4 Cancer of larynx Neoplasms 0.985 0.887 – 1.09 0.773 386 3857 all phecode
149.5
Hx of malignant neoplasm of oral cavity and
Hx of malignant neoplasm of oral cavity and pharynx
 Neoplasms 0.913 0.837 – 0.995 0.0392 552 5505 all phecode
149.9 Cancer of of nasal cavities Neoplasms 1.01 0.883 – 1.15 0.92 240 2398 all phecode
150 Cancer of esophagus Neoplasms 1.04 0.946 – 1.15 0.386 433 4315 all phecode
151 Cancer of stomach Neoplasms 1.05 0.954 – 1.15 0.33 498 4962 all phecode
153 Colorectal cancer Neoplasms 1.03 0.975 – 1.09 0.286 1458 14383 all phecode
153.2 Colon cancer Neoplasms 1.04 0.976 – 1.1 0.242 1160 11472 all phecode
153.3
Malignant neoplasm of rectum, rectosigmoid
Malignant neoplasm of rectum, rectosigmoid junction, and anus
 Neoplasms 1.04 0.965 – 1.12 0.319 815 8093 all phecode
155 Cancer of liver and intrahepatic bile duct Neoplasms 1.04 0.95 – 1.15 0.372 511 5097 all phecode
155.1 Malignant neoplasm of liver, primary Neoplasms 1.08 0.961 – 1.21 0.198 344 3433 all phecode
157 Pancreatic cancer Neoplasms 0.934 0.852 – 1.02 0.142 503 5005 all phecode
158
Neoplasm of unspecified nature of digestive
Neoplasm of unspecified nature of digestive system
 Neoplasms 0.953 0.905 – 1 0.0645 1623 15759 all phecode
159
Malignant neoplasm of other and ill-defined
Malignant neoplasm of other and ill-defined sites within the digestive organs and peritoneum
 Neoplasms 1.01 0.965 – 1.06 0.593 1818 17869 all phecode
159.2
Malignant neoplasm of small intestine
Malignant neoplasm of small intestine, including duodenum
 Neoplasms 1.19 1.04 – 1.37 0.0129 221 2206 all phecode
159.3
Malignant neoplasm of gallbladder and
Malignant neoplasm of gallbladder and extrahepatic bile ducts
 Neoplasms 0.856 0.726 – 1.01 0.0645 158 1578 all phecode
159.4
Malignant neoplasm of retroperitoneum and
Malignant neoplasm of retroperitoneum and peritoneum
 Neoplasms 1.02 0.904 – 1.15 0.754 293 2920 all phecode
164 Cancer of intrathoracic organs Neoplasms 1.03 0.864 – 1.22 0.762 133 1324 all phecode
165 Cancer within the respiratory system Neoplasms 0.957 0.905 – 1.01 0.123 1336 13340 all phecode
165.1 Cancer of bronchus; lung Neoplasms 0.947 0.889 – 1.01 0.089 1057 10552 all phecode
170 Cancer of bone and connective tissue Neoplasms 0.983 0.936 – 1.03 0.48 1792 17850 all phecode
170.1 Bone cancer Neoplasms 0.947 0.88 – 1.02 0.144 773 7690 all phecode
170.2 Cancer of connective tissue Neoplasms 0.987 0.932 – 1.05 0.656 1266 12632 all phecode
172 Skin cancer Neoplasms 0.996 0.972 – 1.02 0.767 8608 33186 all phecode
172.1 Melanomas of skin, dx or hx Neoplasms 0.995 0.966 – 1.03 0.752 5330 30106 all phecode
172.11 Melanomas of skin Neoplasms 0.992 0.955 – 1.03 0.661 3100 25064 all phecode
172.2 Other non-epithelial cancer of skin Neoplasms 0.99 0.964 – 1.02 0.482 7095 30462 all phecode
172.21 Basal cell carcinoma Neoplasms 1.02 0.987 – 1.06 0.219 3690 23868 all phecode
172.22 Squamous cell carcinoma Neoplasms 1 0.961 – 1.05 0.894 2414 17683 all phecode
172.3 Carcinoma in situ of skin Neoplasms 1.05 0.997 – 1.11 0.0649 1482 12326 all phecode
173 Neoplasm of uncertain behavior of skin Neoplasms 0.991 0.946 – 1.04 0.704 1997 18755 all phecode
174 Breast cancer Neoplasms 0.999 0.961 – 1.04 0.979 3186 15514 all phecode
174.1 Breast cancer [female] Neoplasms 1 0.963 – 1.04 0.903 3036 14701 all phecode
174.11 Malignant neoplasm of female breast Neoplasms 1.01 0.968 – 1.05 0.716 2991 14639 all phecode
174.3 Neoplasm of uncertain behavior of breast Neoplasms 1.11 0.968 – 1.26 0.138 233 2307 all phecode
175 Acquired absence of breast Neoplasms 1.02 0.955 – 1.1 0.513 919 8920 all phecode
180 Cervical cancer and dysplasia Neoplasms 0.974 0.922 – 1.03 0.344 1431 12185 all phecode
180.1 Cervical cancer Neoplasms 0.934 0.853 – 1.02 0.145 500 4982 all phecode
180.3
Cervical intraepithelial neoplasia [CIN]
Cervical intraepithelial neoplasia [CIN] [Cervical dysplasia]
 Neoplasms 0.965 0.905 – 1.03 0.285 1048 9323 all phecode
182 Malignant neoplasm of uterus Neoplasms 0.927 0.861 – 0.999 0.0467 765 7613 all phecode
184 Cancer of other female genital organs Neoplasms 0.975 0.919 – 1.03 0.407 1191 11592 all phecode
184.1
Malignant neoplasm of ovary and other uterine
Malignant neoplasm of ovary and other uterine adnexa
 Neoplasms 0.967 0.887 – 1.05 0.448 573 5719 all phecode
184.11 Malignant neoplasm of ovary Neoplasms 0.996 0.901 – 1.1 0.936 432 4309 all phecode
184.2
Cancer of other female genital organs
Cancer of other female genital organs (excluding uterus and ovary)
 Neoplasms 0.959 0.881 – 1.04 0.323 608 6057 all phecode
185 Cancer of prostate Neoplasms 0.984 0.943 – 1.03 0.452 2901 10342 all phecode
187 Cancer of other male genital organs Neoplasms 1.01 0.903 – 1.13 0.841 339 3384 all phecode
187.1
Malignant neoplasm of unspecified male genital
Malignant neoplasm of unspecified male genital organ
 Neoplasms 0.984 0.806 – 1.2 0.879 115 1141 all phecode
187.2 Malignant neoplasm of testis Neoplasms 0.97 0.833 – 1.13 0.694 183 1830 all phecode
187.8
Neoplasm of uncertain behavior of male genital
Neoplasm of uncertain behavior of male genital organs
 Neoplasms 1.03 0.782 – 1.36 0.835 57 562 all phecode
189
Cancer of urinary organs (incl. kidney and
Cancer of urinary organs (incl. kidney and bladder)
 Neoplasms 1 0.965 – 1.04 0.896 2923 23541 all phecode
189.1 Cancer of kidney and renal pelvis Neoplasms 1.02 0.964 – 1.07 0.528 1450 14437 all phecode
189.11 Malignant neoplasm of kidney, except pelvis Neoplasms 1.02 0.967 – 1.08 0.415 1267 12655 all phecode
189.12 Malignant neoplasm of renal pelvis Neoplasms 0.991 0.869 – 1.13 0.89 237 2347 all phecode
189.2 Cancer of bladder Neoplasms 0.993 0.946 – 1.04 0.786 1783 15224 all phecode
189.21 Malignant neoplasm of bladder Neoplasms 0.983 0.934 – 1.03 0.503 1657 14178 all phecode
189.4 Malignant neoplasm of other urinary organs Neoplasms 1.02 0.947 – 1.11 0.56 678 6586 all phecode
190 Cancer of eye Neoplasms 0.931 0.778 – 1.11 0.436 138 1374 all phecode
191
Manlignant and unknown neoplasms of brain and
Manlignant and unknown neoplasms of brain and nervous system
 Neoplasms 0.971 0.912 – 1.03 0.356 1078 10771 all phecode
191.1 Cancer of brain and nervous system Neoplasms 0.981 0.909 – 1.06 0.625 706 7052 all phecode
191.11 Cancer of brain Neoplasms 0.998 0.918 – 1.08 0.96 600 5996 all phecode
193 Thyroid cancer Neoplasms 0.955 0.893 – 1.02 0.179 945 9393 all phecode
194 Cancer of other endocrine glands Neoplasms 0.946 0.868 – 1.03 0.204 579 5759 all phecode
195 Cancer, suspected or other Neoplasms 1.01 0.985 – 1.03 0.57 16962 26401 all phecode
195.1 Malignant neoplasm, other Neoplasms 1.01 0.986 – 1.03 0.505 16670 26384 all phecode
195.3 Malignant neoplasm of head, face, and neck Neoplasms 1 0.943 – 1.07 0.904 1103 9766 all phecode
196 Radiotherapy Neoplasms 1 0.961 – 1.05 0.873 2427 17006 all phecode
197 Chemotherapy Neoplasms 1.03 0.995 – 1.06 0.0958 4952 23797 all phecode
198 Secondary malignant neoplasm Neoplasms 1.02 0.991 – 1.05 0.179 5801 23481 all phecode
198.1 Secondary malignancy of lymph nodes Neoplasms 1.02 0.987 – 1.06 0.224 3677 21489 all phecode
198.2 Secondary malignancy of respiratory organs Neoplasms 0.96 0.902 – 1.02 0.207 1072 10334 all phecode
198.3
Secondary malignant neoplasm of digestive
Secondary malignant neoplasm of digestive systems
 Neoplasms 1.02 0.952 – 1.1 0.554 866 8538 all phecode
198.4 Secondary malignant neoplasm of liver Neoplasms 1.08 1 – 1.17 0.0422 767 7558 all phecode
198.5 Secondary malignancy of brain/spine Neoplasms 0.993 0.915 – 1.08 0.876 640 6338 all phecode
198.6 Secondary malignancy of bone Neoplasms 1.04 0.973 – 1.12 0.233 866 8307 all phecode
198.7 Secondary malignant neoplasm of skin Neoplasms 0.942 0.842 – 1.05 0.301 336 3253 all phecode
199 Neoplasm of uncertain behavior Neoplasms 0.994 0.965 – 1.02 0.706 5693 25767 all phecode
199.4 Neurofibromatosis Neoplasms 0.969 0.781 – 1.2 0.774 88 880 all phecode
200 Myeloproliferative disease Neoplasms 0.972 0.914 – 1.03 0.368 1113 11098 all phecode
200.1 Polycythemia vera Neoplasms 0.952 0.833 – 1.09 0.47 231 2310 all phecode
201 Hodgkin's disease Neoplasms 0.895 0.767 – 1.04 0.158 172 1705 all phecode
202 Cancer of other lymphoid, histiocytic tissue Neoplasms 0.975 0.925 – 1.03 0.338 1559 15571 all phecode
202.2 Non-Hodgkins lymphoma Neoplasms 0.96 0.907 – 1.02 0.156 1329 13268 all phecode
202.21 Nodular lymphoma Neoplasms 0.898 0.831 – 0.971 0.0067 693 6923 all phecode
202.22 Reticulosarcoma Neoplasms 0.91 0.778 – 1.07 0.242 170 1693 all phecode
202.24 Large cell lymphoma Neoplasms 0.886 0.753 – 1.04 0.145 160 1586 all phecode
204 Leukemia Neoplasms 1 0.926 – 1.08 0.968 689 6876 all phecode
204.1 Lymphoid leukemia Neoplasms 0.882 0.773 – 1.01 0.0603 236 2354 all phecode
204.11 Lymphoid leukemia, acute Neoplasms 0.907 0.713 – 1.15 0.429 74 734 all phecode
204.12 Lymphoid leukemia, chronic Neoplasms 0.862 0.741 – 1 0.0551 173 1724 all phecode
204.2 Myeloid leukemia Neoplasms 1.05 0.92 – 1.19 0.494 265 2633 all phecode
204.21 Myeloid leukemia, acute Neoplasms 1.01 0.85 – 1.19 0.949 153 1516 all phecode
204.22 Myeloid leukemia, chronic Neoplasms 1.21 0.931 – 1.57 0.154 61 610 all phecode
204.4 Multiple myeloma Neoplasms 1.07 0.933 – 1.23 0.328 217 2162 all phecode
208 Benign neoplasm of colon Neoplasms 1.01 0.991 – 1.04 0.255 10303 34953 all phecode
209 Neuroendocrine tumors Neoplasms 1.01 0.892 – 1.15 0.855 258 2580 all phecode
210 Benign neoplasm of lip, oral cavity, and pharynx Neoplasms 0.989 0.943 – 1.04 0.649 1891 18839 all phecode
211
Benign neoplasm of other parts of digestive
Benign neoplasm of other parts of digestive system
 Neoplasms 0.982 0.957 – 1.01 0.156 7329 36606 all phecode
212
Benign neoplasm of respiratory and
Benign neoplasm of respiratory and intrathoracic organs
 Neoplasms 1.01 0.961 – 1.06 0.734 1843 18412 all phecode
213 Benign neoplasm of bone and articular cartilage Neoplasms 0.967 0.919 – 1.02 0.197 1677 15527 all phecode
214 Lipoma Neoplasms 1.05 0.998 – 1.11 0.059 1437 14132 all phecode
214.1 Lipoma of skin and subcutaneous tissue Neoplasms 1.05 0.982 – 1.13 0.143 883 8710 all phecode
215
Other benign neoplasm of connective and other
Other benign neoplasm of connective and other soft tissue
 Neoplasms 0.983 0.953 – 1.01 0.288 4528 39509 all phecode
216 Benign neoplasm of skin Neoplasms 1.01 0.986 – 1.03 0.491 11528 34919 all phecode
216.1 Screening for malignant neoplasms of the skin Neoplasms 0.935 0.797 – 1.1 0.413 174 1701 all phecode
217 Vascular hamartomas and non-neoplastic nevi Neoplasms 0.992 0.945 – 1.04 0.753 1786 17184 all phecode
217.1 Nevus, non-neoplastic Neoplasms 1 0.951 – 1.05 0.986 1679 16116 all phecode
218 Benign neoplasm of uterus Neoplasms 0.964 0.932 – 0.997 0.0341 4301 16661 all phecode
218.1 Uterine leiomyoma Neoplasms 0.938 0.893 – 0.985 0.0101 1835 15733 all phecode
218.2 Other benign neoplasm of uterus Neoplasms 0.958 0.923 – 0.994 0.0234 3403 16447 all phecode
220 Benign neoplasm of ovary Neoplasms 1 0.936 – 1.08 0.931 893 8783 all phecode
221 Benign neoplasm of other female genital organs Neoplasms 0.978 0.933 – 1.02 0.343 2042 14248 all phecode
222 Benign neoplasm of male genital organs Neoplasms 0.972 0.915 – 1.03 0.365 1133 10663 all phecode
223
Benign neoplasm of kidney and other urinary
Benign neoplasm of kidney and other urinary organs
 Neoplasms 1 0.955 – 1.06 0.856 1801 12657 all phecode
224 Benign neoplasm of eye Neoplasms 0.969 0.896 – 1.05 0.437 691 6752 all phecode
224.1 Benign neoplasm of eye, uveal Neoplasms 0.992 0.911 – 1.08 0.846 595 5773 all phecode
225
Benign neoplasm of brain and other parts of
Benign neoplasm of brain and other parts of nervous system
 Neoplasms 0.969 0.913 – 1.03 0.29 1209 12074 all phecode
225.1
Benign neoplasm of brain, cranial nerves
Benign neoplasm of brain, cranial nerves, meninges
 Neoplasms 0.96 0.898 – 1.03 0.228 947 9454 all phecode
225.2 Benign neoplasm of spinal cord, meninges Neoplasms 1.06 0.937 – 1.2 0.348 289 2890 all phecode
226 Benign neoplasm of thyroid glands Neoplasms 0.969 0.916 – 1.03 0.272 1329 13264 all phecode
227
Benign neoplasm of other endocrine glands and
Benign neoplasm of other endocrine glands and related structures
 Neoplasms 0.968 0.92 – 1.02 0.199 1690 16896 all phecode
227.1 Benign neoplasm of adrenal gland Neoplasms 1.06 0.965 – 1.17 0.216 467 4644 all phecode
227.2 Benign neoplasm of parathyroid gland Neoplasms 0.975 0.905 – 1.05 0.496 795 7941 all phecode
227.3
Benign neoplasm of pituitary gland and
Benign neoplasm of pituitary gland and craniopharyngeal duct (pouch)
 Neoplasms 0.921 0.834 – 1.02 0.102 435 4350 all phecode
228 Hemangioma and lymphangioma, any site Neoplasms 1.01 0.968 – 1.06 0.599 2149 20946 all phecode
228.1 Hemangioma of skin and subcutaneous tissue Neoplasms 1 0.949 – 1.06 0.888 1356 13336 all phecode
229 Benign neoplasm of unspecified sites Neoplasms 0.983 0.959 – 1.01 0.176 7767 36615 all phecode
229.1 Benign neoplasm of lymph nodes Neoplasms 0.983 0.956 – 1.01 0.23 5743 34218 all phecode
240 Simple and unspecified goiter Endocrine/metabolic 0.981 0.92 – 1.05 0.563 1031 9761 all phecode
241 Nontoxic nodular goiter Endocrine/metabolic 0.984 0.946 – 1.02 0.411 2910 22227 all phecode
241.1 Nontoxic uninodular goiter Endocrine/metabolic 1 0.959 – 1.05 0.947 2265 19902 all phecode
241.2 Nontoxic multinodular goiter Endocrine/metabolic 0.978 0.924 – 1.04 0.455 1304 12479 all phecode
242 Thyrotoxicosis with or without goiter Endocrine/metabolic 0.968 0.915 – 1.02 0.245 1400 13425 all phecode
242.1 Graves' disease Endocrine/metabolic 0.973 0.888 – 1.07 0.56 515 5068 all phecode
242.2 Toxic multinodular goiter Endocrine/metabolic 0.982 0.81 – 1.19 0.851 124 1224 all phecode
242.3 Exophthalmos Endocrine/metabolic 1.06 0.944 – 1.2 0.311 292 2898 all phecode
242.31 Thyrotoxic exophthalmos Endocrine/metabolic 0.901 0.759 – 1.07 0.236 144 1432 all phecode
244 Hypothyroidism Endocrine/metabolic 0.994 0.969 – 1.02 0.655 8099 32717 all phecode
244.1 Secondary hypothyroidism Endocrine/metabolic 0.982 0.934 – 1.03 0.46 1762 17230 all phecode
244.2 Acquired hypothyroidism Endocrine/metabolic 1.06 0.997 – 1.12 0.0623 1261 11982 all phecode
244.4 Hypothyroidism NOS Endocrine/metabolic 0.999 0.973 – 1.03 0.936 7542 32208 all phecode
245 Thyroiditis Endocrine/metabolic 1 0.932 – 1.08 0.937 832 7882 all phecode
245.2 Chronic thyroiditis Endocrine/metabolic 0.983 0.907 – 1.06 0.673 686 6517 all phecode
245.21 Chronic lymphocytic thyroiditis Endocrine/metabolic 0.974 0.899 – 1.06 0.526 679 6449 all phecode
246 Other disorders of thyroid Endocrine/metabolic 0.955 0.929 – 0.983 0.00154 6129 30240 all phecode
246.2 Thyroid cyst Endocrine/metabolic 0.885 0.717 – 1.09 0.253 101 960 all phecode
246.7 Abnormal results of function study of thyroid Endocrine/metabolic 1 0.936 – 1.07 0.948 886 8696 all phecode
249 Secondary diabetes mellitus Endocrine/metabolic 0.943 0.88 – 1.01 0.0923 1150 8340 all phecode
250 Diabetes mellitus Endocrine/metabolic 0.988 0.967 – 1.01 0.264 13947 31815 all phecode
250.1 Type 1 diabetes Endocrine/metabolic 0.941 0.888 – 0.998 0.0417 2364 11758 all phecode
250.11 Type 1 diabetes with ketoacidosis Endocrine/metabolic 0.922 0.777 – 1.09 0.354 262 960 all phecode
250.12 Type 1 diabetes with renal manifestations Endocrine/metabolic 0.948 0.846 – 1.06 0.364 551 2686 all phecode
250.13 Type 1 diabetes with ophthalmic manifestations Endocrine/metabolic 0.955 0.858 – 1.06 0.406 784 3018 all phecode
250.14 Type 1 diabetes with neurological manifestations Endocrine/metabolic 1.01 0.899 – 1.13 0.9 638 2675 all phecode
250.15
Diabetes type 1 with peripheral circulatory
Diabetes type 1 with peripheral circulatory disorders
 Endocrine/metabolic 0.918 0.752 – 1.12 0.397 155 850 all phecode
250.2 Type 2 diabetes Endocrine/metabolic 0.973 0.949 – 0.997 0.0294 9843 29688 all phecode
250.21 Type 2 diabetes with ketoacidosis Endocrine/metabolic 0.942 0.809 – 1.1 0.443 282 1327 all phecode
250.22 Type 2 diabetes with renal manifestations Endocrine/metabolic 0.984 0.932 – 1.04 0.552 1941 13510 all phecode
250.23 Type 2 diabetes with ophthalmic manifestations Endocrine/metabolic 0.98 0.919 – 1.05 0.548 1643 9668 all phecode
250.24 Type 2 diabetes with neurological manifestations Endocrine/metabolic 0.983 0.936 – 1.03 0.48 2557 16502 all phecode
250.25
Diabetes type 2 with peripheral circulatory
Diabetes type 2 with peripheral circulatory disorders
 Endocrine/metabolic 1.05 0.972 – 1.14 0.21 860 6143 all phecode
250.3 Insulin pump user Endocrine/metabolic 0.971 0.93 – 1.01 0.188 3496 20809 all phecode
250.4 Abnormal glucose Endocrine/metabolic 1.01 0.983 – 1.04 0.502 8385 30645 all phecode
250.41 Impaired fasting glucose Endocrine/metabolic 0.991 0.942 – 1.04 0.713 1870 15861 all phecode
250.42 Other abnormal glucose Endocrine/metabolic 1.01 0.987 – 1.04 0.306 7553 30071 all phecode
250.5 Glycosuria or Acetonuria Endocrine/metabolic 1.06 0.874 – 1.29 0.543 136 1067 all phecode
250.6 Polyneuropathy in diabetes Endocrine/metabolic 0.981 0.929 – 1.04 0.493 2132 13390 all phecode
250.7 Diabetic retinopathy Endocrine/metabolic 0.978 0.926 – 1.03 0.42 1691 10517 all phecode
251 Other disorders of pancreatic internal secretion Endocrine/metabolic 1.01 0.943 – 1.08 0.83 991 8469 all phecode
251.1 Hypoglycemia Endocrine/metabolic 1.02 0.953 – 1.09 0.565 1207 8570 all phecode
252 Disorders of parathyroid gland Endocrine/metabolic 1.01 0.968 – 1.06 0.626 2282 22119 all phecode
252.1 Hyperparathyroidism Endocrine/metabolic 1.01 0.966 – 1.06 0.651 2088 20335 all phecode
252.2 Hypoparathyroidism Endocrine/metabolic 1.02 0.932 – 1.12 0.638 508 5073 all phecode
253
Disorders of the pituitary gland and its
Disorders of the pituitary gland and its hypothalamic control
 Endocrine/metabolic 1.01 0.943 – 1.08 0.767 859 8544 all phecode
253.1 Pituitary hyperfunction Endocrine/metabolic 0.939 0.827 – 1.07 0.331 263 2621 all phecode
253.11 Acromegaly and gigantism Endocrine/metabolic 0.975 0.782 – 1.22 0.822 83 826 all phecode
253.2 Pituitary hypofunction Endocrine/metabolic 0.95 0.831 – 1.09 0.456 226 2250 all phecode
253.3 Diabetes insipidus Endocrine/metabolic 0.889 0.713 – 1.11 0.297 86 860 all phecode
253.4 Anterior pituitary disorders Endocrine/metabolic 0.925 0.768 – 1.11 0.409 121 1209 all phecode
253.7 Other disorders of neurohypophysis Endocrine/metabolic 1.2 0.99 – 1.46 0.0631 108 1080 all phecode
255 Disorders of adrenal glands Endocrine/metabolic 0.972 0.922 – 1.03 0.299 1506 14869 all phecode
255.1 Adrenal hyperfunction Endocrine/metabolic 0.976 0.878 – 1.09 0.661 373 3730 all phecode
255.11 Cushing's syndrome Endocrine/metabolic 0.97 0.832 – 1.13 0.698 183 1830 all phecode
255.12 Hyperaldosteronism Endocrine/metabolic 1.1 0.92 – 1.33 0.289 135 1350 all phecode
255.2 Adrenal hypofunction Endocrine/metabolic 0.996 0.917 – 1.08 0.929 626 6239 all phecode
255.21 Glucocorticoid deficiency Endocrine/metabolic 0.996 0.915 – 1.08 0.919 596 5941 all phecode
256 Ovarian dysfunction Endocrine/metabolic 0.974 0.916 – 1.04 0.399 1146 10513 all phecode
256.4 Polycystic ovaries Endocrine/metabolic 0.969 0.898 – 1.05 0.413 742 7128 all phecode
257 Testicular dysfunction Endocrine/metabolic 0.978 0.915 – 1.04 0.501 1015 9238 all phecode
257.1 Testicular hypofunction Endocrine/metabolic 0.989 0.925 – 1.06 0.757 983 8933 all phecode
258 Iatrogenic endocrine disorders Endocrine/metabolic 1.04 0.835 – 1.29 0.73 91 910 all phecode
258.1 Postablative ovarian failure Endocrine/metabolic 0.929 0.767 – 1.13 0.453 109 1090 all phecode
259 Other endocrine disorders Endocrine/metabolic 1 0.941 – 1.07 0.917 1038 10259 all phecode
260 Protein-calorie malnutrition Endocrine/metabolic 1.02 0.981 – 1.06 0.328 2880 26812 all phecode
260.1 Cachexia Endocrine/metabolic 1.06 0.935 – 1.19 0.381 292 2911 all phecode
260.2 severe protein-calorie malnutrition Endocrine/metabolic 1.03 0.977 – 1.08 0.297 1691 16847 all phecode
260.22 Nutritional marasmus Endocrine/metabolic 0.986 0.907 – 1.07 0.734 614 6140 all phecode
260.3 Adult failure to thrive Endocrine/metabolic 1.02 0.936 – 1.1 0.713 629 6236 all phecode
260.6 Anorexia Endocrine/metabolic 1.04 0.97 – 1.12 0.264 868 8591 all phecode
260.7 Polyphagia Endocrine/metabolic 1.03 0.799 – 1.34 0.804 65 643 all phecode
261 Vitamin deficiency Endocrine/metabolic 1.01 0.98 – 1.03 0.669 7718 35203 all phecode
261.1 Vitamin A deficiency Endocrine/metabolic 0.97 0.759 – 1.24 0.809 69 690 all phecode
261.2 Vitamin B-complex deficiencies Endocrine/metabolic 0.979 0.913 – 1.05 0.554 857 8405 all phecode
261.4 Vitamin D deficiency Endocrine/metabolic 1.01 0.985 – 1.04 0.425 7255 35225 all phecode
261.41 Rickets or osteomalacia Endocrine/metabolic 0.976 0.737 – 1.29 0.863 52 511 all phecode
262 Mineral deficiency NEC Endocrine/metabolic 1.01 0.949 – 1.07 0.808 1182 11676 all phecode
263 Other nutritional deficiency Endocrine/metabolic 1.01 0.962 – 1.07 0.641 1651 15788 all phecode
264 Lack of normal physiological development Endocrine/metabolic 0.992 0.868 – 1.13 0.904 239 2301 all phecode
264.2 Failure to thrive (childhood) Endocrine/metabolic 1.07 0.892 – 1.29 0.451 122 1220 all phecode
264.9
Lack of normal physiological development
Lack of normal physiological development, unspecified
 Endocrine/metabolic 0.863 0.687 – 1.08 0.203 81 772 all phecode
269 Proteinuria Endocrine/metabolic 1.04 0.986 – 1.09 0.16 1694 13981 all phecode
270
Disorders of protein plasma/amino-acid
Disorders of protein plasma/amino-acid transport and metabolism
 Endocrine/metabolic 0.993 0.929 – 1.06 0.83 967 9575 all phecode
270.1 Disturbances of amino-acid transport Endocrine/metabolic 0.941 0.801 – 1.11 0.462 170 1697 all phecode
270.11
Disturbances of sulphur-bearing amino-acid
Disturbances of sulphur-bearing amino-acid metabolism
 Endocrine/metabolic 0.924 0.769 – 1.11 0.396 134 1334 all phecode
270.2 Disorders of amino-acid metabolism Endocrine/metabolic 0.777 0.634 – 0.953 0.0154 96 954 all phecode
270.3 Disorders of plasma protein metabolism Endocrine/metabolic 1.04 0.964 – 1.12 0.316 737 7303 all phecode
270.32 Paraproteinemia Endocrine/metabolic 1.05 0.948 – 1.17 0.336 384 3781 all phecode
270.33 Amyloidosis Endocrine/metabolic 1.06 0.84 – 1.33 0.644 71 695 all phecode
270.34 Alpha-1-antitrypsin deficiency Endocrine/metabolic 0.991 0.789 – 1.24 0.939 69 690 all phecode
270.38
Other specified disorders of plasma protein
Other specified disorders of plasma protein metabolism
 Endocrine/metabolic 1.04 0.921 – 1.17 0.533 299 2984 all phecode
271
Disorders of carbohydrate transport and
Disorders of carbohydrate transport and metabolism
 Endocrine/metabolic 0.995 0.958 – 1.03 0.814 2907 28132 all phecode
271.3
Intestinal disaccharidase deficiencies and
Intestinal disaccharidase deficiencies and disaccharide malabsorption
 Endocrine/metabolic 0.997 0.959 – 1.04 0.887 2827 27425 all phecode
271.9
Other disorders of carbohydrate transport and
Other disorders of carbohydrate transport and metabolism
 Endocrine/metabolic 0.886 0.73 – 1.08 0.222 102 1007 all phecode
272 Disorders of lipoid metabolism Endocrine/metabolic 1.35 1.32 – 1.38 1.92e-170 18881 26670 all phecode
272.1 Hyperlipidemia Endocrine/metabolic 1.35 1.33 – 1.38 2.53e-171 18843 26654 all phecode
272.11 Hypercholesterolemia Endocrine/metabolic 1.49 1.44 – 1.54 6.67e-129 5928 21600 all phecode
272.12 Hyperglyceridemia Endocrine/metabolic 1.13 1.07 – 1.2 1.91e-05 1360 11837 all phecode
272.13 Mixed hyperlipidemia Endocrine/metabolic 1.39 1.33 – 1.44 1.35e-58 3538 18449 all phecode
272.9 Unspecified disorder of lipoid metabolism Endocrine/metabolic 1.21 1.08 – 1.36 0.00157 313 3011 all phecode
274 Gout and other crystal arthropathies Endocrine/metabolic 1 0.963 – 1.05 0.863 2524 22729 all phecode
274.1 Gout Endocrine/metabolic 1.01 0.965 – 1.05 0.749 2409 21991 all phecode
274.11 Gouty arthropathy Endocrine/metabolic 0.999 0.939 – 1.06 0.987 1082 10576 all phecode
274.2 Crystal arthropathies Endocrine/metabolic 1.02 0.874 – 1.18 0.845 195 1890 all phecode
274.21 Chondrocalcinosis Endocrine/metabolic 1.01 0.866 – 1.18 0.886 183 1772 all phecode
275 Disorders of mineral metabolism Endocrine/metabolic 0.983 0.953 – 1.01 0.292 4357 37091 all phecode
275.1 Disorders of iron metabolism Hematopoietic 0.868 0.755 – 0.998 0.0473 218 2180 all phecode
275.11 Hereditary hemochromatosis Hematopoietic 0.773 0.636 – 0.94 0.0097 99 990 all phecode
275.2 Disorders of copper metabolism Endocrine/metabolic 0.877 0.679 – 1.13 0.311 62 614 all phecode
275.3 Disorders of magnesium metabolism Endocrine/metabolic 1.02 0.956 – 1.08 0.609 1154 11504 all phecode
275.5 Disorders of calcium/phosphorus metabolism Endocrine/metabolic 0.977 0.943 – 1.01 0.208 3369 31544 all phecode
275.51 Hypocalcemia Endocrine/metabolic 0.926 0.865 – 0.992 0.0288 898 8969 all phecode
275.53 Disorders of phosphorus metabolism Endocrine/metabolic 0.964 0.912 – 1.02 0.187 1366 13634 all phecode
275.6 Hypercalcemia Endocrine/metabolic 1 0.949 – 1.06 0.955 1468 14183 all phecode
276
Disorders of fluid, electrolyte, and acid-base
Disorders of fluid, electrolyte, and acid-base balance
 Endocrine/metabolic 1 0.98 – 1.03 0.79 9238 37046 all phecode
276.1 Electrolyte imbalance Endocrine/metabolic 1 0.976 – 1.03 0.858 6352 34366 all phecode
276.11 Hyperosmolality and/or hypernatremia Endocrine/metabolic 1.01 0.925 – 1.1 0.852 550 5434 all phecode
276.12 Hyposmolality and/or hyponatremia Endocrine/metabolic 1.02 0.978 – 1.06 0.359 2514 23219 all phecode
276.13 Hyperpotassemia Endocrine/metabolic 0.986 0.949 – 1.02 0.465 2992 25216 all phecode
276.14 Hypopotassemia Endocrine/metabolic 1.01 0.962 – 1.05 0.794 2148 20909 all phecode
276.4 Acid-base balance disorder Endocrine/metabolic 1.01 0.97 – 1.06 0.531 2086 20332 all phecode
276.41 Acidosis Endocrine/metabolic 1 0.953 – 1.05 0.993 1788 17572 all phecode
276.42 Alkalosis Endocrine/metabolic 1.08 0.98 – 1.18 0.123 476 4741 all phecode
276.5 Hypovolemia Endocrine/metabolic 1.01 0.978 – 1.04 0.597 4574 34527 all phecode
276.6 Fluid overload Endocrine/metabolic 0.975 0.922 – 1.03 0.366 1384 13211 all phecode
276.8 Polydipsia Endocrine/metabolic 1.14 0.942 – 1.38 0.177 124 1240 all phecode
277 Other disorders of metabolism Endocrine/metabolic 1 0.97 – 1.04 0.874 4112 35070 all phecode
277.2
Other disorders of purine and pyrimidine
Other disorders of purine and pyrimidine metabolism
 Endocrine/metabolic 0.962 0.867 – 1.07 0.465 403 3991 all phecode
277.4 Disorders of bilirubin excretion Endocrine/metabolic 0.975 0.902 – 1.05 0.514 720 7161 all phecode
277.5 Other disorders of lipoid metabolism Endocrine/metabolic 0.942 0.88 – 1.01 0.0851 936 9270 all phecode
277.51 Lipoprotein disorders Endocrine/metabolic 0.933 0.865 – 1.01 0.0694 773 7668 all phecode
277.7 Dysmetabolic syndrome X Endocrine/metabolic 1.04 0.974 – 1.12 0.229 916 8359 all phecode
278 Overweight, obesity and other hyperalimentation Endocrine/metabolic 0.988 0.969 – 1.01 0.192 19419 27331 all phecode
278.1 Obesity Endocrine/metabolic 0.984 0.965 – 1 0.103 17129 27321 all phecode
278.11 Morbid obesity Endocrine/metabolic 0.972 0.948 – 0.997 0.0257 8280 27172 all phecode
278.3 Localized adiposity Endocrine/metabolic 0.847 0.756 – 0.949 0.00434 324 3228 all phecode
278.4 Abnormal weight gain Endocrine/metabolic 1.01 0.96 – 1.05 0.829 2104 17411 all phecode
279 Disorders involving the immune mechanism Endocrine/metabolic 0.982 0.945 – 1.02 0.342 2934 28612 all phecode
279.1 Immunity deficiency Endocrine/metabolic 0.988 0.929 – 1.05 0.692 1161 11571 all phecode
279.11 Deficiency of humoral immunity Endocrine/metabolic 0.98 0.876 – 1.1 0.73 330 3278 all phecode
279.2 Autoimmune disease NEC Endocrine/metabolic 0.975 0.903 – 1.05 0.506 754 7516 all phecode
279.7 Other immunological findings Endocrine/metabolic 1.01 0.977 – 1.04 0.669 4885 36552 all phecode
279.8
Other specified disorders involving the immune
Other specified disorders involving the immune mechanism
 Endocrine/metabolic 0.949 0.872 – 1.03 0.217 601 5988 all phecode
280 Iron deficiency anemias Hematopoietic 1.03 0.998 – 1.06 0.0695 4626 30873 all phecode
280.1
Iron deficiency anemias, unspecified or not due
Iron deficiency anemias, unspecified or not due to blood loss
 Hematopoietic 1.03 0.994 – 1.06 0.107 4484 30649 all phecode
280.2
Iron deficiency anemia secondary to blood loss
Iron deficiency anemia secondary to blood loss (chronic)
 Hematopoietic 1.02 0.975 – 1.08 0.337 1771 17196 all phecode
281 Other deficiency anemia Hematopoietic 0.979 0.894 – 1.07 0.648 519 5120 all phecode
281.1 Megaloblastic anemia Hematopoietic 0.943 0.828 – 1.07 0.37 253 2497 all phecode
281.11 Pernicious anemia Hematopoietic 0.873 0.719 – 1.06 0.171 114 1108 all phecode
281.12 Other vitamin B12 deficiency anemia Hematopoietic 0.958 0.826 – 1.11 0.572 187 1817 all phecode
281.9 Deficiency anemias Hematopoietic 0.996 0.879 – 1.13 0.956 285 2830 all phecode
282 Hereditary hemolytic anemias Hematopoietic 0.953 0.849 – 1.07 0.418 323 3188 all phecode
282.8 Other hemoglobinopathies Hematopoietic 0.887 0.771 – 1.02 0.0917 216 2113 all phecode
282.9 Other hereditary hemolytic anemias Hematopoietic 1.01 0.866 – 1.17 0.934 192 1920 all phecode
283 Acquired hemolytic anemias Hematopoietic 0.978 0.826 – 1.16 0.794 155 1550 all phecode
283.1 Autoimmune hemolytic anemias Hematopoietic 1.08 0.833 – 1.39 0.569 64 633 all phecode
284 Aplastic anemia Hematopoietic 1.03 0.95 – 1.11 0.487 697 6943 all phecode
284.1 Pancytopenia Hematopoietic 1.05 0.967 – 1.15 0.237 612 6100 all phecode
285 Other anemias Hematopoietic 1.01 0.991 – 1.03 0.255 11794 33591 all phecode
285.1 Acute posthemorrhagic anemia Hematopoietic 1.01 0.978 – 1.05 0.456 3325 27709 all phecode
285.2 Anemia of chronic disease Hematopoietic 1.03 0.98 – 1.07 0.27 2055 19939 all phecode
285.21 Anemia in chronic kidney disease Hematopoietic 1 0.937 – 1.07 0.943 932 9106 all phecode
285.22 Anemia in neoplastic disease Hematopoietic 1.01 0.934 – 1.1 0.772 690 6892 all phecode
286 Coagulation defects Hematopoietic 1.01 0.979 – 1.05 0.467 3844 33384 all phecode
286.1 Congenital coagulation defects Hematopoietic 0.918 0.806 – 1.05 0.201 250 2466 all phecode
286.11 Von willebrand's disease Hematopoietic 0.988 0.786 – 1.24 0.918 83 822 all phecode
286.12
Congenital deficiency of other clotting factors
Congenital deficiency of other clotting factors (including factor VII)
 Hematopoietic 0.862 0.721 – 1.03 0.103 126 1260 all phecode
286.2
Encounter for long-term (current) use of
Encounter for long-term (current) use of anticoagulants
 Hematopoietic 1.02 0.979 – 1.05 0.411 3354 25918 all phecode
286.3
Coagulation defects complicating pregnancy or
Coagulation defects complicating pregnancy or postpartum
 Hematopoietic 0.744 0.609 – 0.909 0.00374 97 962 all phecode
286.4 Acquired coagulation factor deficiency Hematopoietic 0.99 0.87 – 1.13 0.88 254 2529 all phecode
286.5
Hemorrhagic disorder due to intrinsic
Hemorrhagic disorder due to intrinsic circulating anticoagulants
 Hematopoietic 1.13 0.94 – 1.35 0.197 132 1294 all phecode
286.6 Defibrination syndrome Hematopoietic 1 0.964 – 1.05 0.844 2579 25377 all phecode
286.7 Other and unspecified coagulation defects Hematopoietic 1 0.966 – 1.04 0.878 3014 29294 all phecode
286.8 Hypercoagulable state Hematopoietic 0.987 0.92 – 1.06 0.721 846 8437 all phecode
286.81 Primary hypercoagulable state Hematopoietic 0.975 0.907 – 1.05 0.492 813 8111 all phecode
286.9 Abnormal coagulation profile Hematopoietic 1.03 0.968 – 1.09 0.361 1182 11487 all phecode
287 Purpura and other hemorrhagic conditions Hematopoietic 1.04 1 – 1.08 0.0369 3288 28474 all phecode
287.1 Spontaneous ecchymoses Hematopoietic 1.11 0.959 – 1.28 0.167 211 2094 all phecode
287.3 Thrombocytopenia Hematopoietic 1.04 1 – 1.08 0.0311 2938 26323 all phecode
287.31 Primary thrombocytopenia Hematopoietic 1.07 0.979 – 1.16 0.141 601 5994 all phecode
287.32 Secondary thrombocytopenia Hematopoietic 1.03 0.941 – 1.12 0.557 569 5686 all phecode
287.4 Qualitative platelet defects Hematopoietic 1.17 0.964 – 1.41 0.113 112 1120 all phecode
288 Diseases of white blood cells Hematopoietic 0.983 0.954 – 1.01 0.269 4886 36527 all phecode
288.1 Decreased white blood cell count Hematopoietic 0.986 0.936 – 1.04 0.601 1599 15951 all phecode
288.11 Neutropenia Hematopoietic 0.967 0.908 – 1.03 0.297 1106 11041 all phecode
288.2 Elevated white blood cell count Hematopoietic 0.977 0.946 – 1.01 0.168 4082 35079 all phecode
288.3 Eosinophilia Hematopoietic 0.912 0.789 – 1.05 0.208 187 1866 all phecode
289 Other diseases of blood and blood-forming organs Hematopoietic 0.975 0.928 – 1.02 0.303 1757 17434 all phecode
289.3
Personal history of diseases of blood and
Personal history of diseases of blood and blood-forming organs
 Hematopoietic 1.03 0.96 – 1.1 0.421 918 9087 all phecode
289.4 Lymphadenitis Hematopoietic 0.979 0.947 – 1.01 0.216 3888 34715 all phecode
289.5 Diseases of spleen Hematopoietic 1.02 0.918 – 1.13 0.721 393 3913 all phecode
289.8 Polycythemia, secondary Hematopoietic 0.886 0.781 – 1 0.0588 255 2550 all phecode
289.9 Abnormality of red blood cells Hematopoietic 0.944 0.852 – 1.05 0.268 385 3813 all phecode
290
Delirium dementia and amnestic and other
Delirium dementia and amnestic and other cognitive disorders
 Mental Disorders 1.03 0.97 – 1.09 0.363 1318 11547 all phecode
290.1 Dementias Mental Disorders 1.08 0.988 – 1.18 0.0899 541 4910 all phecode
290.11 Alzheimer's disease Mental Disorders 1.2 1.02 – 1.43 0.0302 151 1389 all phecode
290.12 Dementia with cerebral degenerations Mental Disorders 0.927 0.745 – 1.15 0.499 88 846 all phecode
290.13 Senile dementia Mental Disorders 1.08 0.97 – 1.21 0.154 340 3078 all phecode
290.16 Vascular dementia Mental Disorders 1.07 0.851 – 1.35 0.556 81 777 all phecode
290.2 Delirium due to conditions classified elsewhere Mental Disorders 0.987 0.916 – 1.06 0.732 750 7358 all phecode
290.3
Other persistent mental disorders due to
Other persistent mental disorders due to conditions classified elsewhere
 Mental Disorders 1.07 0.997 – 1.15 0.0617 886 8618 all phecode
291
Other specified nonpsychotic and/or transient
Other specified nonpsychotic and/or transient mental disorders
 Mental Disorders 0.986 0.946 – 1.03 0.491 2550 24810 all phecode
291.1
Transient mental disorders due to conditions
Transient mental disorders due to conditions classified elsewhere
 Mental Disorders 0.933 0.803 – 1.08 0.365 175 1750 all phecode
291.4
Specific nonpsychotic mental disorders due to
Specific nonpsychotic mental disorders due to brain damage
 Mental Disorders 1.01 0.919 – 1.11 0.851 484 4807 all phecode
291.8 Alteration of consciousness Mental Disorders 0.996 0.952 – 1.04 0.878 2036 19974 all phecode
292 Neurological disorders Mental Disorders 0.984 0.957 – 1.01 0.263 5733 38553 all phecode
292.1 Aphasia/speech disturbance Mental Disorders 0.986 0.942 – 1.03 0.552 2013 19867 all phecode
292.11 Aphasia Mental Disorders 0.98 0.904 – 1.06 0.615 664 6581 all phecode
292.12 Symbolic dysfunction Mental Disorders 0.899 0.778 – 1.04 0.15 200 1988 all phecode
292.2 Mild cognitive impairment Mental Disorders 1.05 0.945 – 1.17 0.363 389 3731 all phecode
292.3 Memory loss Mental Disorders 1.03 0.979 – 1.08 0.278 1922 18158 all phecode
292.4 Altered mental status Mental Disorders 0.97 0.93 – 1.01 0.148 2454 22725 all phecode
292.5 Transient alteration of awareness Mental Disorders 0.956 0.866 – 1.06 0.376 430 4285 all phecode
292.6 Hallucinations Mental Disorders 0.869 0.761 – 0.992 0.0373 217 2147 all phecode
293 Symptoms involving head and neck Mental Disorders 0.954 0.862 – 1.06 0.359 414 4127 all phecode
293.1
Swelling, mass, or lump in head and neck
Swelling, mass, or lump in head and neck [Space-occupying lesion, intracranial NOS]
 Mental Disorders 1 0.969 – 1.03 0.985 4417 38609 all phecode
295 Schizophrenia and other psychotic disorders Mental Disorders 0.944 0.88 – 1.01 0.105 885 8229 all phecode
295.1 Schizophrenia Mental Disorders 0.967 0.809 – 1.16 0.713 138 1339 all phecode
295.2 Paranoid disorders Mental Disorders 0.821 0.681 – 0.991 0.0397 118 1079 all phecode
295.3 Psychosis Mental Disorders 0.955 0.883 – 1.03 0.246 716 6694 all phecode
296 Mood disorders Mental Disorders 1 0.981 – 1.02 0.853 15356 20858 all phecode
296.1 Bipolar Mental Disorders 0.986 0.93 – 1.04 0.626 1301 11264 all phecode
296.2 Depression Mental Disorders 1 0.981 – 1.02 0.798 14833 20856 all phecode
296.22 Major depressive disorder Mental Disorders 1 0.979 – 1.02 0.966 13850 20853 all phecode
297 Suicidal ideation or attempt Mental Disorders 0.967 0.904 – 1.03 0.321 985 9050 all phecode
297.1 Suicidal ideation Mental Disorders 0.993 0.921 – 1.07 0.857 788 7310 all phecode
297.2 Suicide or self-inflicted injury Mental Disorders 0.954 0.844 – 1.08 0.454 285 2654 all phecode
300 Anxiety disorders Mental Disorders 0.996 0.975 – 1.02 0.746 15419 20850 all phecode
300.1 Anxiety disorder Mental Disorders 0.999 0.977 – 1.02 0.897 14517 20855 all phecode
300.11 Generalized anxiety disorder Mental Disorders 0.986 0.956 – 1.02 0.377 5546 20512 all phecode
300.12 Agorophobia, social phobia, and panic disorder Mental Disorders 0.994 0.938 – 1.05 0.848 1360 11377 all phecode
300.13 Phobia Mental Disorders 0.966 0.904 – 1.03 0.301 1051 9542 all phecode
300.3 Obsessive-compulsive disorders Mental Disorders 0.879 0.781 – 0.989 0.0315 328 3018 all phecode
300.4 Dysthymic disorder Mental Disorders 0.993 0.95 – 1.04 0.744 2420 16552 all phecode
300.8 Acute reaction to stress Mental Disorders 0.959 0.874 – 1.05 0.375 504 4825 all phecode
300.9 Posttraumatic stress disorder Mental Disorders 1 0.931 – 1.08 0.98 843 7909 all phecode
301 Personality disorders Mental Disorders 0.991 0.899 – 1.09 0.854 477 4539 all phecode
301.2 Antisocial/borderline personality disorder Mental Disorders 1.04 0.906 – 1.18 0.613 254 2393 all phecode
302 Sexual and gender identity disorders Mental Disorders 0.965 0.93 – 1 0.0625 3700 13808 all phecode
302.1 Decreased libido Mental Disorders 0.887 0.804 – 0.98 0.0182 447 4331 all phecode
303 Psychogenic and somatoform disorders Mental Disorders 1.01 0.98 – 1.04 0.591 6808 20043 all phecode
303.1 Dissociative disorder Mental Disorders 0.933 0.794 – 1.1 0.402 161 1573 all phecode
303.3 Psychogenic disorder Mental Disorders 1.01 0.979 – 1.04 0.632 6487 19888 all phecode
303.31
Gastrointestinal malfunction arising from
Gastrointestinal malfunction arising from mental factors
 Mental Disorders 0.947 0.859 – 1.04 0.276 471 4623 all phecode
303.4 Somatoform disorder Mental Disorders 1.02 0.96 – 1.08 0.53 1177 11180 all phecode
304 Adjustment reaction Mental Disorders 1 0.966 – 1.04 0.985 3888 20475 all phecode
305.2 Eating disorder Mental Disorders 0.959 0.895 – 1.03 0.24 901 8329 all phecode
306 Other mental disorder Mental Disorders 0.983 0.935 – 1.03 0.488 1815 14133 all phecode
306.1 Mental disorders durring/after pregnancy Mental Disorders 1.03 0.94 – 1.13 0.539 587 3527 all phecode
306.9 Tension headache Mental Disorders 0.983 0.911 – 1.06 0.664 753 7277 all phecode
312 Conduct disorders Mental Disorders 0.969 0.852 – 1.1 0.628 254 2501 all phecode
312.3 Impulse control disorder Mental Disorders 0.995 0.778 – 1.27 0.966 74 736 all phecode
313 Pervasive developmental disorders Mental Disorders 0.992 0.941 – 1.05 0.762 1571 14633 all phecode
313.1 Attention deficit hyperactivity disorder Mental Disorders 0.985 0.932 – 1.04 0.607 1392 13190 all phecode
313.2 Tics and stuttering Mental Disorders 1.05 0.837 – 1.32 0.662 77 770 all phecode
313.3 Autism Mental Disorders 1.04 0.808 – 1.34 0.758 64 621 all phecode
315 Develomental delays and disorders Mental Disorders 1.02 0.944 – 1.1 0.607 684 6788 all phecode
315.1 Learning disorder Mental Disorders 1.09 0.872 – 1.36 0.457 87 860 all phecode
315.2 Speech and language disorder Mental Disorders 1.08 0.949 – 1.23 0.24 254 2539 all phecode
316 Substance addiction and disorders Mental Disorders 0.989 0.955 – 1.02 0.511 3682 32680 all phecode
316.1 Polyneuropathy due to drugs Mental Disorders 0.985 0.907 – 1.07 0.711 634 6331 all phecode
317 Alcohol-related disorders Mental Disorders 1.01 0.972 – 1.06 0.533 2525 22920 all phecode
317.1 Alcoholism Mental Disorders 1.02 0.969 – 1.06 0.527 1986 19339 all phecode
317.11 Alcoholic liver damage Mental Disorders 0.961 0.868 – 1.06 0.44 408 4080 all phecode
318 Tobacco use disorder Mental Disorders 1.01 0.987 – 1.03 0.387 8622 34842 all phecode
320 Meningitis Neurological 1.08 0.971 – 1.2 0.159 382 3820 all phecode
323 Encephalitis Neurological 1.03 0.889 – 1.2 0.666 181 1809 all phecode
323.8 Encephalitis, non-infectious Neurological 1.01 0.857 – 1.18 0.924 153 1527 all phecode
324 Other CNS infection and poliomyelitis Neurological 0.993 0.882 – 1.12 0.902 288 2880 all phecode
325
Phlebitis and thrombophlebitis of intracranial
Phlebitis and thrombophlebitis of intracranial venous sinuses
 Neurological 0.964 0.725 – 1.28 0.799 53 530 all phecode
327 Sleep disorders Neurological 0.993 0.974 – 1.01 0.484 14941 31602 all phecode
327.1 Hypersomnia Neurological 0.996 0.951 – 1.04 0.851 2061 19110 all phecode
327.3 Sleep apnea Neurological 0.998 0.976 – 1.02 0.842 10909 31304 all phecode
327.31 Central/nonobstroctive sleep apnea Neurological 0.963 0.877 – 1.06 0.423 492 4784 all phecode
327.32 Obstructive sleep apnea Neurological 0.995 0.971 – 1.02 0.688 8744 30530 all phecode
327.4 Insomnia Neurological 0.986 0.958 – 1.02 0.353 5524 30960 all phecode
327.41 Organic or persistent insomnia Neurological 0.963 0.908 – 1.02 0.204 1265 12120 all phecode
327.5 Parasomnia Neurological 0.929 0.855 – 1.01 0.0851 604 5913 all phecode
327.6 Circadian rhythm sleep disorder Neurological 0.831 0.732 – 0.944 0.00424 274 2666 all phecode
327.7 Sleep related movement disorders Neurological 0.961 0.916 – 1.01 0.113 1786 17323 all phecode
327.71 Restless legs syndrome Neurological 0.951 0.903 – 1 0.0552 1570 15360 all phecode
327.72 Sleep related leg cramps Neurological 1.12 0.894 – 1.4 0.327 83 822 all phecode
331 Other cerebral degenerations Neurological 1.03 0.957 – 1.12 0.401 717 7024 all phecode
331.1 Hydrocephalus Neurological 0.957 0.848 – 1.08 0.48 284 2836 all phecode
331.9 Cerebral degeneration, unspecified Neurological 1.06 0.96 – 1.18 0.243 419 4026 all phecode
332 Parkinson's disease Neurological 0.903 0.818 – 0.998 0.0464 415 4128 all phecode
333
Extrapyramidal disease and abnormal movement
Extrapyramidal disease and abnormal movement disorders
 Neurological 0.976 0.939 – 1.01 0.224 2868 26583 all phecode
333.1 Essential tremor Neurological 0.974 0.903 – 1.05 0.498 725 7163 all phecode
333.2 Myoclonus Neurological 1.16 0.986 – 1.37 0.072 159 1590 all phecode
333.4 Torsion dystonia Neurological 1.01 0.907 – 1.13 0.812 352 3504 all phecode
333.8 Other degenerative diseases of the basal ganglia Neurological 0.978 0.785 – 1.22 0.84 89 890 all phecode
334 Degenerative disease of the spinal cord Neurological 0.95 0.892 – 1.01 0.113 1058 10562 all phecode
334.1 Spinocerebellar disease Neurological 0.843 0.664 – 1.07 0.162 79 790 all phecode
334.2 Anterior horn cell disease Neurological 0.797 0.66 – 0.961 0.0174 110 1080 all phecode
334.21 Amyotrophic Lateral Sclerosis Neurological 0.752 0.601 – 0.94 0.0123 71 693 all phecode
335 Multiple sclerosis Neurological 0.992 0.894 – 1.1 0.873 396 3951 all phecode
337 Disorders of the autonomic nervous system Neurological 0.927 0.863 – 0.996 0.0397 808 7413 all phecode
337.1 Peripheral autonomic neuropathy Neurological 0.944 0.847 – 1.05 0.3 370 3164 all phecode
338 Pain Neurological 0.999 0.98 – 1.02 0.886 20346 26417 all phecode
338.1 Acute pain Neurological 0.994 0.975 – 1.01 0.584 15582 26313 all phecode
338.2 Chronic pain Neurological 1 0.978 – 1.02 0.984 10994 26368 all phecode
339 Other headache syndromes Neurological 1 0.979 – 1.03 0.853 9242 34658 all phecode
340 Migraine Neurological 1 0.975 – 1.03 0.868 6708 30587 all phecode
340.1 Migrain with aura Neurological 1.02 0.984 – 1.06 0.282 3624 23684 all phecode
341
Other demyelinating diseases of central nervous
Other demyelinating diseases of central nervous system
 Neurological 0.992 0.829 – 1.19 0.932 133 1330 all phecode
342 Hemiplegia Neurological 0.95 0.864 – 1.05 0.294 464 4607 all phecode
343 Infantile cerebral palsy Neurological 0.989 0.795 – 1.23 0.922 85 847 all phecode
344 Other paralytic syndromes Neurological 1.05 0.972 – 1.14 0.213 682 6808 all phecode
345 Epilepsy, recurrent seizures, convulsions Neurological 0.963 0.925 – 1 0.0715 2553 25307 all phecode
345.1 Epilepsy Neurological 0.892 0.827 – 0.961 0.0026 747 7465 all phecode
345.11 Generalized convulsive epilepsy Neurological 0.906 0.792 – 1.04 0.153 233 2330 all phecode
345.12 Partial epilepsy Neurological 0.903 0.827 – 0.987 0.0238 534 5335 all phecode
345.3 Convulsions Neurological 0.954 0.915 – 0.995 0.0277 2396 23796 all phecode
346
Abnormal findings on study of brain and/or
Abnormal findings on study of brain and/or nervous system
 Neurological 0.989 0.849 – 1.15 0.884 183 1824 all phecode
346.1
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of skull and head
 Neurological 1.01 0.955 – 1.06 0.784 1472 14587 all phecode
346.2
Nonspecific abnormal results of function study
Nonspecific abnormal results of function study of brain and central nervous system
 Neurological 1.02 0.847 – 1.24 0.808 120 1181 all phecode
346.3
Nonspecific abnormal findings in cerebrospinal
Nonspecific abnormal findings in cerebrospinal fluid
 Neurological 0.794 0.659 – 0.956 0.0149 110 1100 all phecode
347 Cataplexy and narcolepsy Neurological 1.01 0.824 – 1.23 0.945 101 1010 all phecode
348 Other conditions of brain Neurological 0.99 0.943 – 1.04 0.677 1793 17894 all phecode
348.2 Cerebral edema and compression of brain Neurological 0.962 0.899 – 1.03 0.264 905 9034 all phecode
348.4 Cerebral cysts Neurological 0.97 0.848 – 1.11 0.663 229 2290 all phecode
348.7 Coma Neurological 1.11 0.97 – 1.28 0.125 229 2275 all phecode
348.8 Encephalopathy, not elsewhere classified Neurological 1.03 0.959 – 1.1 0.427 853 8479 all phecode
348.9 Other conditions of brain, NOS Neurological 0.998 0.957 – 1.04 0.941 2341 23287 all phecode
349
Other and unspecified disorders of the nervous
Other and unspecified disorders of the nervous system
 Neurological 1.02 0.95 – 1.09 0.645 941 9385 all phecode
350 Abnormal movement Neurological 0.985 0.959 – 1.01 0.251 6706 38762 all phecode
350.1 Abnormal involuntary movements Neurological 0.992 0.956 – 1.03 0.65 3273 30524 all phecode
350.2 Abnormality of gait Neurological 0.969 0.937 – 1 0.0695 3920 30520 all phecode
350.3 Lack of coordination Neurological 0.982 0.921 – 1.05 0.569 1062 10554 all phecode
350.5 Abnormal reflex Neurological 0.902 0.781 – 1.04 0.161 200 1988 all phecode
350.6 Disturbances of sensation of smell and taste Neurological 1.01 0.93 – 1.11 0.749 558 5576 all phecode
351 Other peripheral nerve disorders Neurological 0.996 0.971 – 1.02 0.749 7401 34460 all phecode
352 Disorders of other cranial nerves Neurological 0.971 0.924 – 1.02 0.254 1714 17106 all phecode
352.1 Trigeminal nerve disorders [CN5] Neurological 0.888 0.813 – 0.971 0.00918 535 5344 all phecode
352.2 Facial nerve disorders [CN7] Neurological 0.975 0.905 – 1.05 0.508 783 7826 all phecode
353 Nerve root and plexus disorders Neurological 0.99 0.959 – 1.02 0.558 4256 33369 all phecode
353.1 Nerve plexus lesions Neurological 1.01 0.908 – 1.12 0.87 390 3900 all phecode
353.2 Nerve root lesions Neurological 0.903 0.761 – 1.07 0.245 130 1287 all phecode
355 Complex regional/central pain syndrome Neurological 0.886 0.81 – 0.969 0.00784 531 5295 all phecode
355.1 Chronic pain syndrome Neurological 0.995 0.927 – 1.07 0.885 843 8386 all phecode
356 Hereditary and idiopathic peripheral neuropathy Neurological 0.972 0.931 – 1.01 0.196 2335 20731 all phecode
357 Inflammatory and toxic neuropathy Neurological 0.993 0.959 – 1.03 0.699 3472 29956 all phecode
358 Myoneural disorders Neurological 0.993 0.935 – 1.06 0.823 1147 11391 all phecode
358.1 Myasthenia gravis Neurological 1.02 0.834 – 1.26 0.815 109 1082 all phecode
359 Muscular dystrophies and other myopathies Neurological 0.947 0.891 – 1.01 0.0823 1134 11274 all phecode
359.1 Muscular dystrophies Neurological 0.77 0.595 – 0.995 0.0457 64 632 all phecode
359.2 Myopathy Neurological 0.952 0.895 – 1.01 0.124 1092 10843 all phecode
360 Disorders of the globe Sense Organs 1 0.836 – 1.2 0.996 131 1276 all phecode
360.2 Progressive myopia Sense Organs 1.02 0.795 – 1.3 0.899 65 640 all phecode
361 Retinal detachments and defects Sense Organs 0.955 0.886 – 1.03 0.231 733 7131 all phecode
361.1 Retinal detachment with retinal defect Sense Organs 0.982 0.875 – 1.1 0.764 302 2962 all phecode
362 Other retinal disorders Sense Organs 1.02 0.985 – 1.06 0.26 3569 22997 all phecode
362.2
Degeneration of macula and posterior pole of
Degeneration of macula and posterior pole of retina
 Sense Organs 1.05 1 – 1.1 0.0484 2172 15483 all phecode
362.21 Macular degeneration, dry Sense Organs 1.02 0.919 – 1.12 0.756 419 3438 all phecode
362.22 Macular degeneration, wet Sense Organs 0.958 0.81 – 1.13 0.613 148 1184 all phecode
362.23 Cystoid macular degeneration of retina Sense Organs 1.05 0.949 – 1.16 0.347 408 3839 all phecode
362.26 Macular puckering of retina Sense Organs 1.06 0.994 – 1.14 0.0739 976 8610 all phecode
362.27 Drusen (degenerative) of retina Sense Organs 1.04 0.944 – 1.14 0.455 488 4558 all phecode
362.29 Macular degeneration (senile) of retina NOS Sense Organs 1.03 0.981 – 1.08 0.241 1883 13955 all phecode
362.3 Other nondiabetic retinopathy Sense Organs 0.988 0.925 – 1.06 0.727 976 8527 all phecode
362.31 Separation of retinal layers Sense Organs 1 0.907 – 1.11 0.973 413 4056 all phecode
362.4 Retinal vascular changes and abnomalities Sense Organs 0.998 0.921 – 1.08 0.955 662 5933 all phecode
362.6 Peripheral retinal degenerations Sense Organs 1.03 0.935 – 1.15 0.507 392 3787 all phecode
362.7 Hereditary retinal dystrophies Sense Organs 0.995 0.866 – 1.14 0.949 215 2103 all phecode
362.8 Retinal hemorrhage/ischemia Sense Organs 0.885 0.777 – 1.01 0.0648 241 2368 all phecode
362.9 Retinal edema Sense Organs 0.938 0.836 – 1.05 0.276 324 2936 all phecode
363
Chorioretinal inflammations, scars, and other
Chorioretinal inflammations, scars, and other disorders of choroid
 Sense Organs 0.991 0.904 – 1.09 0.851 492 4746 all phecode
363.3 Chorioretinal scars Sense Organs 1.01 0.906 – 1.13 0.813 332 3184 all phecode
364 Corneal opacity and other disorders of cornea Sense Organs 1.02 0.962 – 1.09 0.469 1132 10772 all phecode
364.1 Corneal opacity Sense Organs 0.923 0.83 – 1.03 0.138 394 3846 all phecode
364.2 Corneal edema Sense Organs 0.931 0.767 – 1.13 0.469 123 1208 all phecode
364.4 Corneal degenerations Sense Organs 0.939 0.847 – 1.04 0.236 402 3962 all phecode
364.41 Keratoconus Sense Organs 1.08 0.849 – 1.38 0.518 75 739 all phecode
364.5 Corneal dystrophy Sense Organs 1.15 1.04 – 1.26 0.00407 502 4682 all phecode
364.51 Fuchs' dystrophy Sense Organs 1.07 0.947 – 1.22 0.267 266 2521 all phecode
364.9 Cornea replaced by transplant Sense Organs 1.22 0.987 – 1.51 0.0663 91 885 all phecode
365 Glaucoma Sense Organs 0.999 0.96 – 1.04 0.962 2672 21326 all phecode
365.1 Open-angle glaucoma Sense Organs 0.998 0.924 – 1.08 0.961 705 6491 all phecode
365.11 Primary open angle glaucoma Sense Organs 1.05 0.945 – 1.16 0.381 403 3681 all phecode
365.2 Primary angle-closure glaucoma Sense Organs 1.03 0.906 – 1.18 0.635 251 2370 all phecode
366 Cataract Sense Organs 1.02 0.994 – 1.05 0.137 8611 28043 all phecode
366.1 Nonsenile Cataract Sense Organs 1.04 0.898 – 1.2 0.621 207 1979 all phecode
366.2 Senile cataract Sense Organs 1.03 0.994 – 1.06 0.109 5480 24980 all phecode
367
Disorders of refraction and accommodation
Disorders of refraction and accommodation; blindness and low vision
 Sense Organs 1.01 0.982 – 1.03 0.623 8967 37779 all phecode
367.1 Myopia Sense Organs 1.01 0.983 – 1.04 0.406 5014 34677 all phecode
367.2 Astigmatism Sense Organs 1.01 0.975 – 1.04 0.66 4161 32463 all phecode
367.8 Hypermetropia Sense Organs 1.02 0.975 – 1.07 0.374 2039 18599 all phecode
367.9 Blindness and low vision Sense Organs 0.945 0.892 – 1 0.0524 1277 12356 all phecode
368 Visual disturbances Sense Organs 1.02 0.989 – 1.05 0.238 5715 39599 all phecode
368.1 Amblyopia Sense Organs 1.01 0.934 – 1.1 0.747 651 6479 all phecode
368.2 Diplopia and disorders of binocular vision Sense Organs 0.949 0.892 – 1.01 0.102 1087 10786 all phecode
368.3 Anisometropia Sense Organs 0.871 0.759 – 0.999 0.0491 219 2168 all phecode
368.4 Visual field defects Sense Organs 0.983 0.925 – 1.05 0.592 1132 11173 all phecode
368.9 Subjective visual disturbances Sense Organs 0.984 0.924 – 1.05 0.608 1070 10620 all phecode
368.91 Psychophysical visual disturbances Sense Organs 0.879 0.733 – 1.05 0.165 120 1171 all phecode
369 Infection of the eye Sense Organs 1 0.964 – 1.04 0.98 3185 28240 all phecode
369.2 Eye infection, viral Sense Organs 0.996 0.907 – 1.09 0.936 502 4954 all phecode
369.5 Conjunctivitis, infectious Sense Organs 1 0.961 – 1.04 0.991 2716 24970 all phecode
370 Keratitis Sense Organs 0.972 0.919 – 1.03 0.319 1365 13169 all phecode
370.1 Corneal ulcer Sense Organs 1.1 0.954 – 1.27 0.191 223 2194 all phecode
370.2 Superficial keratitis Sense Organs 0.953 0.871 – 1.04 0.285 546 5393 all phecode
370.3 Keratoconjunctivitis Sense Organs 0.949 0.875 – 1.03 0.208 649 6263 all phecode
370.31 Keratoconjunctivitis sicca Sense Organs 1.04 0.896 – 1.22 0.584 179 1677 all phecode
371 Inflammation of the eye Sense Organs 0.999 0.968 – 1.03 0.966 4414 32310 all phecode
371.1 Uveitis, noninfectious or NOS Sense Organs 1.01 0.921 – 1.1 0.896 541 5278 all phecode
371.2 Conjunctivitis, noninfectious Sense Organs 1 0.935 – 1.07 0.965 906 8939 all phecode
371.21 Allergic conjunctivitis Sense Organs 1.02 0.951 – 1.11 0.522 756 7515 all phecode
371.3 Inflammation of eyelids Sense Organs 0.994 0.959 – 1.03 0.75 3398 26983 all phecode
371.33 Noninfectious dermatoses of eyelid Sense Organs 0.97 0.814 – 1.15 0.728 133 1291 all phecode
372 Disorders of conjunctiva Sense Organs 1.1 1.03 – 1.17 0.00333 1118 10728 all phecode
374 Other disorders of eyelids Sense Organs 1 0.964 – 1.04 0.932 2940 24188 all phecode
374.1 Ectropion or entropion Sense Organs 0.938 0.851 – 1.03 0.2 431 4084 all phecode
374.2 Lagophthalmos Sense Organs 0.892 0.78 – 1.02 0.0938 235 2335 all phecode
374.3 Ptosis of eyelid Sense Organs 0.99 0.931 – 1.05 0.756 1102 10734 all phecode
374.6 Dermatochalasis Sense Organs 1.01 0.95 – 1.08 0.699 1040 9720 all phecode
375 Disorders of lacrimal system Sense Organs 0.967 0.934 – 1 0.0624 3694 26045 all phecode
375.1 Dry eyes Sense Organs 0.992 0.959 – 1.03 0.623 4040 26751 all phecode
375.2 Epiphora Sense Organs 0.92 0.834 – 1.02 0.101 442 4354 all phecode
376 Disorders of the orbit Sense Organs 1.02 0.915 – 1.14 0.714 352 3508 all phecode
377 Disorders of optic nerve and visual pathways Sense Organs 1.05 0.983 – 1.13 0.139 913 9021 all phecode
377.1 Optic atrophy Sense Organs 1.04 0.92 – 1.18 0.529 283 2793 all phecode
377.3 Optic neuritis/neuropathy Sense Organs 1.06 0.976 – 1.16 0.164 585 5775 all phecode
378
Strabismus and other disorders of binocular eye
Strabismus and other disorders of binocular eye movements
 Sense Organs 0.987 0.931 – 1.05 0.644 1275 12460 all phecode
378.1 Strabismus (not specified as paralytic) Sense Organs 0.974 0.907 – 1.05 0.474 828 8130 all phecode
378.2 Nystagmus and other irregular eye movements Sense Organs 0.995 0.849 – 1.16 0.946 170 1686 all phecode
378.5 Paralytic strabismus Sense Organs 0.94 0.842 – 1.05 0.266 349 3437 all phecode
379 Other disorders of eye Sense Organs 1.02 0.99 – 1.05 0.185 5046 29999 all phecode
379.1 Scleritis and episcleritis Sense Organs 0.929 0.791 – 1.09 0.366 176 1743 all phecode
379.2 Disorders of vitreous body Sense Organs 1.03 0.998 – 1.07 0.0674 3634 23186 all phecode
379.3 Aphakia and other disorders of lens Sense Organs 0.878 0.738 – 1.04 0.142 135 1258 all phecode
379.4 Anomalies of pupillary function Sense Organs 0.978 0.867 – 1.1 0.711 287 2833 all phecode
379.5 Disorders of iris and ciliary body Sense Organs 0.933 0.828 – 1.05 0.251 304 2948 all phecode
379.51 Pigmentary iris degeneration Sense Organs 1.03 0.815 – 1.31 0.793 77 731 all phecode
379.9 Pain, swelling or discharge of eye Sense Organs 0.951 0.895 – 1.01 0.111 1129 11130 all phecode
380 Disorders of external ear Sense Organs 1.03 0.984 – 1.07 0.217 2242 20393 all phecode
380.1 Otitis externa Sense Organs 0.998 0.945 – 1.05 0.935 1469 14580 all phecode
380.4 Impacted cerumen Sense Organs 1.03 0.99 – 1.07 0.136 2648 23557 all phecode
381 Otitis media and Eustachian tube disorders Sense Organs 0.985 0.954 – 1.02 0.365 4255 36417 all phecode
381.1 Otitis media Sense Organs 0.983 0.947 – 1.02 0.361 3079 29813 all phecode
381.11 Suppurative and unspecified otitis media Sense Organs 0.983 0.944 – 1.02 0.421 2610 25602 all phecode
381.2 Eustachian tube disorders Sense Organs 0.978 0.932 – 1.03 0.375 1816 17827 all phecode
381.3 Mastoiditis & related conditions Sense Organs 1.11 0.939 – 1.32 0.219 153 1530 all phecode
381.9 Otorrhea Sense Organs 0.962 0.864 – 1.07 0.479 372 3713 all phecode
382 Otalgia Sense Organs 1 0.954 – 1.05 0.969 1884 18673 all phecode
383 Otosclerosis Sense Organs 0.966 0.807 – 1.16 0.705 124 1240 all phecode
384 Other disorders of tympanic membrane Sense Organs 0.953 0.871 – 1.04 0.295 516 5156 all phecode
384.1 Myringitis Sense Organs 0.956 0.722 – 1.27 0.754 51 502 all phecode
384.4 Perforation of tympanic membrane Sense Organs 0.947 0.855 – 1.05 0.295 403 4029 all phecode
385 Other disorders of middle ear and mastoid Sense Organs 0.995 0.901 – 1.1 0.917 432 4320 all phecode
385.3 Cholesteatoma Sense Organs 1 0.886 – 1.13 0.972 277 2770 all phecode
385.5
Tympanosclerosis and middle ear disease related
Tympanosclerosis and middle ear disease related to otitis media
 Sense Organs 0.85 0.707 – 1.02 0.0857 118 1180 all phecode
386
Vertiginous syndromes and other disorders of
Vertiginous syndromes and other disorders of vestibular system
 Sense Organs 1.02 0.973 – 1.07 0.395 1882 18186 all phecode
386.1 Meniere's disease Sense Organs 1.02 0.907 – 1.14 0.756 319 3156 all phecode
386.2 Peripheral or central vertigo Sense Organs 1.03 0.978 – 1.09 0.265 1586 15423 all phecode
386.21 Central origin vertigo Sense Organs 1.06 0.999 – 1.13 0.0542 1208 11844 all phecode
386.3 Labyrinthitis Sense Organs 1.05 0.991 – 1.1 0.105 1482 14530 all phecode
386.9
Dizziness and giddiness (Light-headedness and
Dizziness and giddiness (Light-headedness and vertigo)
 Sense Organs 1.02 0.996 – 1.05 0.105 6933 38286 all phecode
388 Other disorders of ear Sense Organs 1.02 0.956 – 1.09 0.533 960 9501 all phecode
389 Hearing loss Sense Organs 1 0.98 – 1.03 0.739 8182 38069 all phecode
389.1 Sensorineural hearing loss Sense Organs 0.995 0.962 – 1.03 0.746 4107 29258 all phecode
389.2 Conductive hearing loss Sense Organs 0.935 0.873 – 1 0.0527 905 9042 all phecode
389.3 Degenerative and vascular disorders of ear Sense Organs 0.907 0.781 – 1.05 0.203 192 1808 all phecode
389.4 Tinnitus Sense Organs 1.01 0.972 – 1.06 0.504 2291 22130 all phecode
389.5 Disorders of acoustic nerve Sense Organs 1.04 0.87 – 1.25 0.654 124 1229 all phecode
394 Rheumatic disease of the heart valves Circulatory System 1.02 0.966 – 1.08 0.473 1458 13732 all phecode
394.1 Mitral valve stenosis and aortic valve stenosis Circulatory System 1.01 0.908 – 1.13 0.81 350 3415 all phecode
394.2 Mitral valve disease Circulatory System 1.05 0.952 – 1.15 0.339 462 4560 all phecode
394.3 Aortic valve disease Circulatory System 1.03 0.878 – 1.2 0.741 176 1691 all phecode
394.4 Acute rheumatic heart disease Circulatory System 0.78 0.595 – 1.02 0.0717 55 546 all phecode
394.7 Disease of tricuspid valve Circulatory System 1.02 0.939 – 1.11 0.615 587 5739 all phecode
395 Heart valve disorders Circulatory System 1.06 1.03 – 1.1 0.000516 3976 28748 all phecode
395.1 Nonrheumatic mitral valve disorders Circulatory System 1.05 1.01 – 1.1 0.02 2175 20441 all phecode
395.2 Nonrheumatic aortic valve disorders Circulatory System 1.08 1.03 – 1.13 0.000738 2060 17194 all phecode
395.3 Nonrheumatic tricuspid valve disorders Circulatory System 1.07 0.974 – 1.18 0.158 493 4864 all phecode
395.4 Nonrheumatic pulmonary valve disorders Circulatory System 1.02 0.833 – 1.24 0.873 108 1080 all phecode
395.6 Heart valve replaced Circulatory System 1.05 0.99 – 1.12 0.099 1177 10833 all phecode
396 Abnormal heart sounds Circulatory System 1.04 1.01 – 1.07 0.0147 4718 34395 all phecode
401 Hypertension Circulatory System 1.02 1 – 1.04 0.0522 23317 23367 all phecode
401.1 Essential hypertension Circulatory System 1.02 1 – 1.04 0.0503 23158 23364 all phecode
401.2 Hypertensive heart and/or renal disease Circulatory System 1.02 0.976 – 1.06 0.454 3503 14616 all phecode
401.21 Hypertensive heart disease Circulatory System 1.12 1.04 – 1.2 0.00195 893 6607 all phecode
401.22 Hypertensive chronic kidney disease Circulatory System 0.992 0.949 – 1.04 0.725 2584 13072 all phecode
401.3 Other hypertensive complications Circulatory System 1.06 1.01 – 1.1 0.0116 2679 15833 all phecode
411 Ischemic Heart Disease Circulatory System 1.11 1.09 – 1.14 7.05e-17 8807 30299 all phecode
411.1 Unstable angina (intermediate coronary syndrome) Circulatory System 1.23 1.15 – 1.32 5e-09 937 8574 all phecode
411.2 Myocardial infarction Circulatory System 1.13 1.09 – 1.17 1.92e-10 3594 21716 all phecode
411.3 Angina pectoris Circulatory System 1.14 1.09 – 1.19 3.13e-09 2485 18304 all phecode
411.4 Coronary atherosclerosis Circulatory System 1.13 1.1 – 1.16 2.54e-18 7555 27492 all phecode
411.41 Aneurysm and dissection of heart Circulatory System 1.18 0.988 – 1.4 0.0672 156 1529 all phecode
411.8
Other chronic ischemic heart disease
Other chronic ischemic heart disease, unspecified
 Circulatory System 1.14 1.11 – 1.18 7.72e-19 6331 25741 all phecode
411.9
Other acute and subacute forms of ischemic
Other acute and subacute forms of ischemic heart disease
 Circulatory System 1.06 0.96 – 1.17 0.253 442 4211 all phecode
414 Other forms of chronic heart disease Circulatory System 1.13 1.09 – 1.18 1.1e-10 3101 22616 all phecode
414.2 ASCVD Circulatory System 1.17 1.08 – 1.26 0.000106 718 6816 all phecode
415 Pulmonary heart disease Circulatory System 1.01 0.97 – 1.04 0.758 3366 30208 all phecode
415.1 Acute pulmonary heart disease Circulatory System 0.999 0.953 – 1.05 0.96 1912 19014 all phecode
415.11 Pulmonary embolism and infarction, acute Circulatory System 0.998 0.952 – 1.05 0.927 1906 18953 all phecode
415.2 Chronic pulmonary heart disease Circulatory System 1.01 0.964 – 1.06 0.617 1808 17605 all phecode
415.21 Primary pulmonary hypertension Circulatory System 1.02 0.943 – 1.1 0.628 706 7032 all phecode
416 Cardiomegaly Circulatory System 0.953 0.899 – 1.01 0.105 1254 12372 all phecode
418 Nonspecific chest pain Circulatory System 1.03 1 – 1.05 0.0172 12650 33952 all phecode
418.1 Precordial pain Circulatory System 1.08 1.03 – 1.15 0.00352 1471 13782 all phecode
420 Carditis Circulatory System 1.03 0.979 – 1.09 0.239 1588 15680 all phecode
420.1 Myocarditis Circulatory System 1.02 0.827 – 1.26 0.857 97 958 all phecode
420.2 Pericarditis Circulatory System 1.01 0.936 – 1.08 0.885 842 8402 all phecode
420.21 Acute pericarditis Circulatory System 0.931 0.799 – 1.08 0.358 177 1764 all phecode
420.22 Chronic pericarditis Circulatory System 1.04 0.856 – 1.26 0.71 117 1153 all phecode
420.3 Endocarditis Circulatory System 1 0.929 – 1.08 0.993 764 7535 all phecode
425 Cardiomyopathy Circulatory System 1.06 1.01 – 1.11 0.0134 2078 19881 all phecode
425.1 Primary/intrinsic cardiomyopathies Circulatory System 1.06 1.01 – 1.11 0.0208 1989 19025 all phecode
425.11 Hypertrophic obstructive cardiomyopathy Circulatory System 1.04 0.9 – 1.19 0.623 208 2050 all phecode
425.12 Other hypertrophic cardiomyopathy Circulatory System 1.08 0.934 – 1.25 0.292 201 1992 all phecode
425.2 Secondary/extrinsic cardiomyopathies Circulatory System 0.977 0.873 – 1.09 0.687 317 3170 all phecode
425.8 Other cardiomyopathy Circulatory System 0.933 0.751 – 1.16 0.535 95 931 all phecode
426 Cardiac conduction disorders Circulatory System 1.02 1 – 1.05 0.0406 12327 25440 all phecode
426.2 Atrioventricular [AV] block Circulatory System 1.05 1 – 1.11 0.0358 1903 11501 all phecode
426.21 First degree AV block Circulatory System 1.05 0.986 – 1.11 0.139 1313 8899 all phecode
426.22 Mobitz II AV block Circulatory System 1.19 0.925 – 1.54 0.174 64 553 all phecode
426.23 Second degree AV block Circulatory System 1.08 0.94 – 1.25 0.273 216 1925 all phecode
426.24 Atrioventricular block, complete Circulatory System 1.11 1.01 – 1.22 0.0366 461 3823 all phecode
426.25 Other heart block Circulatory System 1.03 0.889 – 1.19 0.69 203 1803 all phecode
426.3 Bundle branch block Circulatory System 1.05 1 – 1.1 0.0344 2306 13999 all phecode
426.31 Right bundle branch block Circulatory System 1.03 0.976 – 1.09 0.263 1423 10758 all phecode
426.32 Left bundle branch block Circulatory System 1.04 0.977 – 1.12 0.203 969 8110 all phecode
426.4 Anomalous atrioventricular excitation Circulatory System 1.04 0.83 – 1.31 0.711 82 820 all phecode
426.7 Abnormal electrocardiogram [ECG] [EKG] Circulatory System 1.02 1 – 1.05 0.0474 10577 25186 all phecode
426.8 Other cardiac conduction disorders Circulatory System 0.98 0.906 – 1.06 0.62 679 6650 all phecode
426.9 Cardiac pacemaker/device in situ Circulatory System 1.05 0.996 – 1.1 0.0681 1754 11536 all phecode
426.91 Cardiac pacemaker in situ Circulatory System 1.04 0.974 – 1.1 0.26 1171 8184 all phecode
426.92 Cardiac defibrillator in situ Circulatory System 1.08 1 – 1.16 0.0457 846 7320 all phecode
427 Cardiac dysrhythmias Circulatory System 1.01 0.989 – 1.03 0.365 17397 25735 all phecode
427.1 Paroxysmal tachycardia, unspecified Circulatory System 1.05 1 – 1.09 0.0389 2474 18178 all phecode
427.11 Paroxysmal supraventricular tachycardia Circulatory System 1.04 0.986 – 1.09 0.15 1595 14293 all phecode
427.12 Paroxysmal ventricular tachycardia Circulatory System 1.07 1.01 – 1.14 0.0273 1181 9915 all phecode
427.2 Atrial fibrillation and flutter Circulatory System 1.02 0.987 – 1.05 0.238 5313 18688 all phecode
427.21 Atrial fibrillation Circulatory System 1.02 0.988 – 1.06 0.221 5188 18409 all phecode
427.22 Atrial flutter Circulatory System 1.03 0.974 – 1.08 0.337 1693 11042 all phecode
427.3 Other specified cardiac dysrhythmias Circulatory System 1.02 0.993 – 1.05 0.15 8688 25552 all phecode
427.4 Cardiac arrest and ventricular fibrillation Circulatory System 1 0.916 – 1.1 0.968 536 5233 all phecode
427.41 Ventricular fibrillation and flutter Circulatory System 1.12 0.974 – 1.3 0.109 216 2118 all phecode
427.42 Cardiac arrest Circulatory System 0.976 0.881 – 1.08 0.637 410 4034 all phecode
427.5 Arrhythmia (cardiac) NOS Circulatory System 1.01 0.987 – 1.04 0.314 6905 25457 all phecode
427.6 Premature beats Circulatory System 1.07 1.02 – 1.11 0.00414 2359 16248 all phecode
427.61 Supraventricular premature beats Circulatory System 1.03 0.952 – 1.12 0.436 670 6287 all phecode
427.7 Tachycardia NOS Circulatory System 1.01 0.981 – 1.04 0.483 5124 25531 all phecode
427.8 Sinoatrial node dysfunction (Bradycardia) Circulatory System 1.04 0.97 – 1.11 0.273 912 7501 all phecode
427.9 Palpitations Circulatory System 1.02 0.99 – 1.06 0.166 4430 24505 all phecode
428 Congestive heart failure; nonhypertensive Circulatory System 1.05 1.02 – 1.09 0.00334 4300 23663 all phecode
428.1 Congestive heart failure (CHF) NOS Circulatory System 1.05 1.01 – 1.09 0.00704 3756 22446 all phecode
428.2 Heart failure NOS Circulatory System 1.05 1.01 – 1.08 0.0122 3701 21722 all phecode
428.3
Heart failure with reduced EF [Systolic or
Heart failure with reduced EF [Systolic or combined heart failure]
 Circulatory System 1.07 1.02 – 1.13 0.00532 1765 14476 all phecode
428.4
Heart failure with preserved EF [Diastolic
Heart failure with preserved EF [Diastolic heart failure]
 Circulatory System 1.02 0.966 – 1.07 0.537 1648 13395 all phecode
429
Ill-defined descriptions and complications of
Ill-defined descriptions and complications of heart disease
 Circulatory System 1.03 1.01 – 1.05 0.00377 12635 32504 all phecode
429.1 Heart transplant/surgery Circulatory System 1.09 1.03 – 1.16 0.00305 1219 11696 all phecode
429.2 Abnormal function study of cardiovascular system Circulatory System 1.05 1.02 – 1.08 0.000491 6322 29232 all phecode
429.3 Symptoms involving cardiovascular system Circulatory System 1.03 1.01 – 1.05 0.0172 9650 32421 all phecode
429.9 Cardiac complications, not elsewhere classified Circulatory System 1.05 0.968 – 1.13 0.254 723 7072 all phecode
430 Intracranial hemorrhage Circulatory System 0.966 0.898 – 1.04 0.355 789 7842 all phecode
430.1 Subarachnoid hemorrhage Circulatory System 0.974 0.858 – 1.11 0.68 261 2610 all phecode
430.2 Intracerebral hemorrhage Circulatory System 0.936 0.842 – 1.04 0.218 368 3671 all phecode
430.3 Subdural hemorrhage Circulatory System 0.955 0.844 – 1.08 0.465 272 2680 all phecode
433 Cerebrovascular disease Circulatory System 1.05 1.02 – 1.08 0.00213 5463 32242 all phecode
433.1 Occlusion and stenosis of precerebral arteries Circulatory System 1.09 1.04 – 1.14 0.000507 1978 16212 all phecode
433.11
Occlusion of cerebral arteries, with cerebral
Occlusion of cerebral arteries, with cerebral infarction
 Circulatory System 1.13 0.994 – 1.28 0.0609 260 2517 all phecode
433.12 Cerebral atherosclerosis Circulatory System 1.09 0.869 – 1.37 0.456 80 789 all phecode
433.2 Occlusion of cerebral arteries Circulatory System 1.03 0.987 – 1.07 0.184 2437 21732 all phecode
433.21
Cerebral artery occlusion, with cerebral
Cerebral artery occlusion, with cerebral infarction
 Circulatory System 1.03 0.985 – 1.07 0.2 2357 21103 all phecode
433.3 Cerebral ischemia Circulatory System 1.03 0.99 – 1.07 0.14 2780 22868 all phecode
433.31 Transient cerebral ischemia Circulatory System 1.02 0.98 – 1.07 0.304 2409 20762 all phecode
433.5 Cerebral aneurysm Circulatory System 1.06 0.964 – 1.16 0.229 474 4724 all phecode
433.6 Acute, but ill-defined cerebrovascular disease Circulatory System 1.04 0.945 – 1.14 0.422 464 4518 all phecode
433.8 Late effects of cerebrovascular disease Circulatory System 1.02 0.942 – 1.1 0.633 695 6822 all phecode
440 Atherosclerosis Circulatory System 1.07 1.03 – 1.12 0.000875 2477 19724 all phecode
440.1 Atherosclerosis of renal artery Circulatory System 1.12 0.982 – 1.29 0.0893 231 2291 all phecode
440.2 Atherosclerosis of the extremities Circulatory System 1.04 0.985 – 1.09 0.166 1516 13532 all phecode
440.21
Atherosclerosis of native arteries of the
Atherosclerosis of native arteries of the extremities with ulceration or gangrene
 Circulatory System 1.1 0.973 – 1.24 0.128 274 2669 all phecode
440.22
Atherosclerosis of native arteries of the
Atherosclerosis of native arteries of the extremities with intermittent claudication
 Circulatory System 1.05 0.982 – 1.12 0.157 1040 9647 all phecode
440.9 Atherosclerosis of aorta Circulatory System 1.11 1.03 – 1.19 0.0041 846 8124 all phecode
441 Vascular insufficiency of intestine Circulatory System 0.979 0.894 – 1.07 0.639 515 5115 all phecode
441.1 Acute vascular insufficiency of intestine Circulatory System 1.01 0.882 – 1.16 0.886 240 2387 all phecode
441.2 Chronic vascular insufficiency of intestine Circulatory System 1.06 0.896 – 1.25 0.507 154 1536 all phecode
442 Other aneurysm Circulatory System 1.04 0.996 – 1.08 0.0786 2779 21466 all phecode
442.1 Aortic aneurysm Circulatory System 1.05 1.01 – 1.1 0.0273 2054 16492 all phecode
442.11 Abdominal aortic aneurysm Circulatory System 1.09 1.03 – 1.16 0.0035 1189 10558 all phecode
442.2 Aneurysm of iliac artery Circulatory System 1.07 0.922 – 1.24 0.382 202 2002 all phecode
442.3 Aneurysm of artery of lower extremity Circulatory System 0.997 0.857 – 1.16 0.971 179 1765 all phecode
442.4 Arterial dissection Circulatory System 1.01 0.865 – 1.17 0.944 184 1840 all phecode
442.8 Aneurysm of other specified artery Circulatory System 1.02 0.921 – 1.13 0.686 399 3978 all phecode
443 Peripheral vascular disease Circulatory System 1.04 1.01 – 1.08 0.0238 3086 24814 all phecode
443.1 Raynaud's syndrome Circulatory System 1 0.927 – 1.08 0.999 742 7390 all phecode
443.7
Peripheral angiopathy in diseases classified
Peripheral angiopathy in diseases classified elsewhere
 Circulatory System 1.12 0.974 – 1.28 0.114 220 2087 all phecode
443.8 Other specified peripheral vascular diseases Circulatory System 1.04 0.995 – 1.08 0.086 2557 21985 all phecode
443.9 Peripheral vascular disease, unspecified Circulatory System 1.05 1.01 – 1.1 0.0208 2341 18862 all phecode
444 Arterial embolism and thrombosis Circulatory System 1.02 0.951 – 1.1 0.569 848 8423 all phecode
444.1
Arterial embolism and thrombosis of lower
Arterial embolism and thrombosis of lower extremity artery
 Circulatory System 0.996 0.887 – 1.12 0.95 313 3099 all phecode
444.2 Embolism and thrombosis of abdominal aorta Circulatory System 1.2 1.01 – 1.42 0.0373 155 1548 all phecode
446 Polyarteritis nodosa and allied conditions Circulatory System 1.05 0.954 – 1.15 0.318 460 4559 all phecode
446.4 Wegener's granulomatosis Circulatory System 1.06 0.874 – 1.29 0.54 109 1075 all phecode
446.5 Giant cell arteritis Circulatory System 1.07 0.855 – 1.34 0.554 79 749 all phecode
446.9 Arteritis NOS Circulatory System 0.989 0.877 – 1.11 0.854 289 2876 all phecode
447 Other disorders of arteries and arterioles Circulatory System 1.06 1.02 – 1.1 0.00672 2647 22765 all phecode
447.1 Stricture of artery Circulatory System 1.06 0.969 – 1.16 0.208 523 5163 all phecode
447.7 Aortic ectasia Circulatory System 1.02 0.952 – 1.1 0.532 804 7938 all phecode
448 Disease of capillaries Circulatory System 0.987 0.931 – 1.05 0.662 1237 12127 all phecode
450 Noninfectious disorders of lymphatic channels Circulatory System 0.958 0.916 – 1 0.0603 2104 20985 all phecode
451 Phlebitis and thrombophlebitis Circulatory System 0.952 0.882 – 1.03 0.204 738 7355 all phecode
451.2
Phlebitis and thrombophlebitis of lower
Phlebitis and thrombophlebitis of lower extremities
 Circulatory System 0.952 0.836 – 1.09 0.465 244 2437 all phecode
452 Other venous embolism and thrombosis Circulatory System 0.982 0.953 – 1.01 0.25 4957 29867 all phecode
452.1 Iatrogenic pulmonary embolism and infarction Circulatory System 0.987 0.871 – 1.12 0.835 276 2747 all phecode
452.2 Deep vein thrombosis [DVT] Circulatory System 0.964 0.929 – 0.999 0.0466 3260 26940 all phecode
452.8 Postphlebitic syndrome Circulatory System 1.06 0.898 – 1.25 0.495 154 1529 all phecode
453 Chronic venous hypertension Circulatory System 1 0.875 – 1.15 0.963 220 2168 all phecode
454 Varicose veins Circulatory System 0.951 0.914 – 0.989 0.0113 2827 24555 all phecode
454.1 Varicose veins of lower extremity Circulatory System 0.953 0.914 – 0.994 0.0249 2469 21426 all phecode
454.11 Varicose veins of lower extremity, symptomtic Circulatory System 0.946 0.898 – 0.996 0.0364 1565 15056 all phecode
455 Hemorrhoids Circulatory System 1.05 1.02 – 1.08 0.00117 5799 29818 all phecode
456 Chronic venous insufficiency [CVI] Circulatory System 0.963 0.928 – 1 0.0512 3097 24898 all phecode
457
Encounter for long-term (current) use of
Encounter for long-term (current) use of anticoagulants, antithrombotics, aspirin
 Circulatory System 1.06 1.02 – 1.11 0.00908 2095 15309 all phecode
457.2
Encounter for long-term (current) use of
Encounter for long-term (current) use of antiplatelets/antithrombotics
 Circulatory System 1.13 1.01 – 1.27 0.0382 324 3221 all phecode
457.3 Encounter for long-term (current) use of aspirin Circulatory System 1.06 1.01 – 1.11 0.0133 1973 14689 all phecode
458 Hypotension Circulatory System 1.01 0.979 – 1.04 0.578 5091 32185 all phecode
458.1 Orthostatic hypotension Circulatory System 0.955 0.903 – 1.01 0.114 1344 12938 all phecode
458.2 Iatrogenic hypotension Circulatory System 1 0.94 – 1.06 0.996 1109 11012 all phecode
458.9 Hypotension NOS Circulatory System 1.01 0.979 – 1.04 0.532 4618 31186 all phecode
459 Other disorders of circulatory system Circulatory System 1.01 0.987 – 1.04 0.365 7825 34792 all phecode
459.1 Hemorrhage NOS Circulatory System 1.01 0.943 – 1.09 0.703 834 8215 all phecode
459.7 Blood vessel replaced Circulatory System 0.993 0.938 – 1.05 0.816 1305 13023 all phecode
459.9 Circulatory disease NEC Circulatory System 1.02 0.989 – 1.04 0.26 6706 33592 all phecode
464 Acute sinusitis Respiratory 0.994 0.964 – 1.02 0.694 4792 32137 all phecode
465
Acute upper respiratory infections of multiple
Acute upper respiratory infections of multiple or unspecified sites
 Respiratory 1.01 0.984 – 1.03 0.547 9601 35915 all phecode
465.2 Acute pharyngitis Respiratory 1.01 0.978 – 1.04 0.613 5310 32365 all phecode
465.4 Acute laryngitis and tracheitis Respiratory 1.08 0.978 – 1.19 0.129 443 4428 all phecode
470 Septal Deviations/Turbinate Hypertrophy Respiratory 0.969 0.923 – 1.02 0.205 1797 17640 all phecode
471 Nasal polyps Respiratory 0.981 0.903 – 1.07 0.656 592 5881 all phecode
472 Chronic pharyngitis and nasopharyngitis Respiratory 0.984 0.937 – 1.03 0.523 1797 16986 all phecode
473 Diseases of the larynx and vocal cords Respiratory 0.987 0.95 – 1.03 0.509 2983 25244 all phecode
473.1 Chronic laryngitis Respiratory 0.934 0.736 – 1.19 0.578 68 674 all phecode
473.3 Paralysis/spasm of vocal cords or larynx Respiratory 1.04 0.961 – 1.13 0.315 628 6254 all phecode
473.4 Voice disturbance Respiratory 1 0.962 – 1.05 0.861 2336 21975 all phecode
474 Acute and chronic tonsillitis Respiratory 1.01 0.942 – 1.08 0.766 880 7892 all phecode
474.1 Acute tonsillitis Respiratory 1.03 0.915 – 1.15 0.66 335 3181 all phecode
474.2 Chronic tonsillitis and adenoiditis Respiratory 1.02 0.944 – 1.11 0.602 700 6445 all phecode
475 Chronic sinusitis Respiratory 0.995 0.964 – 1.03 0.781 4378 27891 all phecode
475.9 Postnasal drip Respiratory 1.01 0.945 – 1.08 0.748 922 9017 all phecode
476 Allergic rhinitis Respiratory 0.993 0.972 – 1.01 0.501 12687 28117 all phecode
477 Epistaxis or throat hemorrhage Respiratory 1.08 1.01 – 1.14 0.0187 1150 11318 all phecode
478 Throat pain Respiratory 1.05 0.949 – 1.16 0.341 426 4195 all phecode
479 Other upper respiratory disease Respiratory 0.997 0.968 – 1.03 0.816 5627 28048 all phecode
480 Pneumonia Respiratory 1.03 0.999 – 1.06 0.0573 5947 37034 all phecode
480.1 Bacterial pneumonia Respiratory 1.02 0.963 – 1.09 0.46 1155 11495 all phecode
480.11 Pneumococcal pneumonia Respiratory 1.04 0.949 – 1.13 0.436 568 5644 all phecode
480.12 Pseudomonal pneumonia Respiratory 1.08 0.912 – 1.27 0.386 153 1523 all phecode
480.13 MRSA pneumonia Respiratory 0.821 0.675 – 0.998 0.0473 117 1165 all phecode
480.2 Viral pneumonia Respiratory 1.08 0.943 – 1.24 0.261 202 1992 all phecode
480.3 Pneumonia due to fungus (mycoses) Respiratory 1.04 0.888 – 1.22 0.634 159 1590 all phecode
480.5 Bronchopneumonia and lung abscess Respiratory 0.916 0.771 – 1.09 0.318 135 1312 all phecode
481 Influenza Respiratory 0.99 0.936 – 1.05 0.738 1355 13284 all phecode
483 Acute bronchitis and bronchiolitis Respiratory 1.01 0.974 – 1.05 0.622 3412 29871 all phecode
495 Asthma Respiratory 0.989 0.965 – 1.01 0.351 8671 33569 all phecode
495.1 Chronic obstructive asthma Respiratory 1.05 0.943 – 1.16 0.397 397 3925 all phecode
495.11 Chronic obstructive asthma with exacerbation Respiratory 1.19 0.947 – 1.49 0.137 81 802 all phecode
495.2 Asthma with exacerbation Respiratory 0.991 0.942 – 1.04 0.724 1629 16033 all phecode
496 Chronic airway obstruction Respiratory 1 0.973 – 1.03 0.866 5343 28343 all phecode
496.1 Emphysema Respiratory 1.02 0.977 – 1.07 0.359 2134 19414 all phecode
496.2 Chronic bronchitis Respiratory 0.999 0.967 – 1.03 0.967 4128 26624 all phecode
496.21 Obstructive chronic bronchitis Respiratory 1.01 0.971 – 1.04 0.766 3747 25467 all phecode
496.3 Bronchiectasis Respiratory 1.06 0.975 – 1.16 0.163 549 5453 all phecode
497 Bronchitis Respiratory 1.01 0.961 – 1.06 0.771 1946 18824 all phecode
498 Acute bronchospasm Respiratory 0.991 0.904 – 1.09 0.854 496 4943 all phecode
499 Cystic fibrosis Respiratory 0.936 0.79 – 1.11 0.441 151 1510 all phecode
500 Lung disease due to external agents Respiratory 0.932 0.855 – 1.02 0.113 557 5551 all phecode
500.1 Extrinsic allergic alveolitis Respiratory 1 0.807 – 1.24 0.995 92 920 all phecode
500.2 Pneumoconiosis Respiratory 0.902 0.73 – 1.12 0.341 78 764 all phecode
501 Pneumonitis due to inhalation of food or vomitus Respiratory 1.06 0.973 – 1.15 0.194 634 6225 all phecode
502 Postinflammatory pulmonary fibrosis Respiratory 1.01 0.936 – 1.08 0.849 815 8076 all phecode
503 Pulmonary congestion and hypostasis Respiratory 1.02 0.949 – 1.09 0.61 835 8243 all phecode
504 Other alveolar and parietoalveolar pneumonopathy Respiratory 0.99 0.909 – 1.08 0.819 595 5878 all phecode
504.1 Idiopathic fibrosing alveolitis Respiratory 1.07 0.952 – 1.2 0.256 311 3084 all phecode
505 Other pulmonary inflamation or edema Respiratory 1.03 0.978 – 1.08 0.276 1638 15749 all phecode
506 Empyema and pneumothorax Respiratory 1.04 0.998 – 1.08 0.065 2894 25235 all phecode
507 Pleurisy; pleural effusion Respiratory 1 0.967 – 1.04 0.809 2916 26208 all phecode
508
Pulmonary collapse; interstitial and
Pulmonary collapse; interstitial and compensatory emphysema
 Respiratory 1.01 0.968 – 1.05 0.634 2382 22588 all phecode
509 Respiratory failure, insufficiency, arrest Respiratory 1.03 0.993 – 1.06 0.118 4032 29477 all phecode
509.1 Respiratory failure Respiratory 1 0.954 – 1.05 0.99 1937 18949 all phecode
509.2 Respiratory insufficiency Respiratory 1.01 0.955 – 1.08 0.646 1174 11679 all phecode
509.3
Pulmonary insufficiency or respiratory failure
Pulmonary insufficiency or respiratory failure following trauma and surgery
 Respiratory 1.02 0.967 – 1.07 0.508 1689 16489 all phecode
509.8
Dependence on respirator [Ventilator] or
Dependence on respirator [Ventilator] or supplemental oxygen
 Respiratory 1.04 0.991 – 1.09 0.108 1741 17249 all phecode
510 Other diseases of lung Respiratory 1.01 0.983 – 1.04 0.429 5503 35907 all phecode
510.2 Lung transplant Respiratory 1.12 0.957 – 1.3 0.162 176 1757 all phecode
512 Other symptoms of respiratory system Respiratory 1.01 0.991 – 1.03 0.298 18621 28154 all phecode
512.1 Wheezing Respiratory 0.985 0.931 – 1.04 0.586 1409 13516 all phecode
512.2 Painful respiration Respiratory 1.01 0.964 – 1.05 0.767 2309 21263 all phecode
512.3 Abnormal chest sounds Respiratory 1.04 0.918 – 1.17 0.56 291 2845 all phecode
512.7 Shortness of breath Respiratory 1.02 0.999 – 1.05 0.0581 10034 28081 all phecode
512.8 Cough Respiratory 0.999 0.976 – 1.02 0.94 9501 28148 all phecode
512.9 Other dyspnea Respiratory 1.02 0.994 – 1.04 0.142 10804 28104 all phecode
513 Respiratory abnormalities Respiratory 1 0.983 – 1.02 0.713 12932 33822 all phecode
513.3 Hypoventilation Respiratory 0.954 0.89 – 1.02 0.18 880 8646 all phecode
513.31 Apnea Respiratory 0.997 0.906 – 1.1 0.951 462 4607 all phecode
513.32 Orthopnea Respiratory 0.937 0.818 – 1.07 0.352 220 2160 all phecode
513.4 Hyperventilation Respiratory 1.02 0.936 – 1.12 0.614 515 5124 all phecode
513.8 Disorders of diaphragm Respiratory 0.994 0.875 – 1.13 0.923 258 2557 all phecode
514 Abnormal findings examination of lungs Respiratory 0.997 0.969 – 1.03 0.848 5365 34834 all phecode
514.1
Abnormal results of function study of pulmonary
Abnormal results of function study of pulmonary system
 Respiratory 1 0.882 – 1.13 0.998 258 2580 all phecode
514.2 Solitary pulmonary nodule Respiratory 0.992 0.955 – 1.03 0.675 3018 27338 all phecode
516 Abnormal sputum Respiratory 0.979 0.908 – 1.06 0.593 735 7332 all phecode
516.1 Hemoptysis Respiratory 0.969 0.892 – 1.05 0.464 611 6080 all phecode
519
Other diseases of respiratory system, not
Other diseases of respiratory system, not elsewhere classified
 Respiratory 1.02 0.988 – 1.04 0.273 6458 39057 all phecode
519.1 Tracheostomy complications Respiratory 1.02 0.88 – 1.17 0.837 214 2136 all phecode
519.2 Respiratory complications Respiratory 0.989 0.898 – 1.09 0.826 445 4430 all phecode
519.8 Other diseases of respiratory system, NEC Respiratory 0.997 0.946 – 1.05 0.916 1588 15787 all phecode
519.9
Symptoms involving respiratory system and other
Symptoms involving respiratory system and other chest symptoms
 Respiratory 1.02 0.988 – 1.05 0.231 4706 34489 all phecode
520 Disorders of tooth development Digestive 1.02 0.914 – 1.13 0.754 369 3690 all phecode
520.1 Hereditary disturbances in tooth structure Digestive 1.03 0.877 – 1.21 0.714 165 1642 all phecode
520.2 Disturbances in tooth eruption Digestive 1.01 0.878 – 1.16 0.915 218 2172 all phecode
521 Diseases of hard tissues of teeth Digestive 0.955 0.891 – 1.02 0.185 898 8954 all phecode
521.1 Dental caries Digestive 0.949 0.884 – 1.02 0.146 837 8349 all phecode
521.2 Dental abrasion, erosion and attrition Digestive 0.966 0.724 – 1.29 0.813 52 510 all phecode
522 Diseases of pulp and periapical tissues Digestive 1.07 0.974 – 1.17 0.164 535 5340 all phecode
522.5 Periapical abscess Digestive 1.05 0.956 – 1.16 0.296 459 4583 all phecode
523 Gingival and periodontal diseases Digestive 1 0.929 – 1.08 0.952 718 7180 all phecode
523.1 Gingivitis Digestive 0.787 0.665 – 0.933 0.00569 142 1418 all phecode
523.3 Periodontitis (acute or chronic) Digestive 1.04 0.936 – 1.15 0.469 364 3636 all phecode
523.31 Acute periodontitis Digestive 1.01 0.899 – 1.13 0.893 311 3109 all phecode
523.32 Chronic periodontitis Digestive 1.12 0.932 – 1.35 0.222 122 1204 all phecode
524 Dentofacial anomalies, including malocclusion Digestive 1.05 0.94 – 1.17 0.397 363 3630 all phecode
524.3 Anomalies of tooth position/malocclusion Digestive 1.07 0.934 – 1.23 0.315 220 2200 all phecode
525
Other diseases of the teeth and supporting
Other diseases of the teeth and supporting structures
 Digestive 1 0.941 – 1.07 0.9 1039 10382 all phecode
525.1 Loss of teeth or edentulism Digestive 0.978 0.879 – 1.09 0.688 374 3731 all phecode
526 Diseases of the jaws Digestive 0.995 0.956 – 1.04 0.793 2680 26455 all phecode
526.1 Cysts of the jaws Digestive 0.946 0.827 – 1.08 0.416 247 2470 all phecode
526.3 Anomalies of jaw size/symmetry Digestive 0.977 0.857 – 1.11 0.723 241 2383 all phecode
526.4 Temporomandibular joint disorders Digestive 1 0.948 – 1.05 0.998 1504 15025 all phecode
526.41 Temporomandibular joint disorder, unspecified Digestive 0.995 0.937 – 1.06 0.877 1187 11858 all phecode
526.42 Arthralgia/ankylosis of temporomandibular joint Digestive 1.02 0.944 – 1.1 0.634 741 7400 all phecode
526.5 Inflammatory conditions of jaw Digestive 1.01 0.897 – 1.14 0.834 287 2864 all phecode
526.8 Exostosis of jaw Digestive 1.11 0.839 – 1.48 0.456 53 521 all phecode
526.9 Jaw disease NOS Digestive 0.948 0.863 – 1.04 0.26 487 4867 all phecode
527 Diseases of the salivary glands Digestive 0.999 0.952 – 1.05 0.969 1781 17771 all phecode
527.1 Hypertrophy of salivary gland Digestive 1.08 0.831 – 1.41 0.553 58 579 all phecode
527.2 Sialoadenitis Digestive 1.08 0.972 – 1.2 0.152 394 3936 all phecode
527.7 Disturbance of salivary secretion Digestive 1.02 0.95 – 1.09 0.654 952 9481 all phecode
527.8 Other specified diseases of the salivary glands Digestive 1.02 0.898 – 1.16 0.754 254 2540 all phecode
528
Diseases of the oral soft tissues, excluding
Diseases of the oral soft tissues, excluding lesions specific for gingiva and tongue
 Digestive 0.989 0.95 – 1.03 0.592 2643 26197 all phecode
528.1 Stomatitis and mucositis Digestive 0.927 0.857 – 1 0.0611 668 6657 all phecode
528.11 Stomatitis and mucositis (ulcerative) Digestive 0.869 0.758 – 0.995 0.0424 211 2110 all phecode
528.12 Oral aphthae Digestive 0.938 0.818 – 1.08 0.36 215 2137 all phecode
528.3 Cellulitis and abscess of oral soft tissues Digestive 0.978 0.855 – 1.12 0.748 235 2338 all phecode
528.4 Cysts of oral soft tissues Digestive 1.06 0.885 – 1.28 0.513 124 1229 all phecode
528.41 Cyst of the salivary gland Digestive 1 0.8 – 1.26 0.982 77 760 all phecode
528.5 Diseases of lips Digestive 1 0.909 – 1.1 0.987 462 4602 all phecode
528.6 Leukoplakia of oral mucosa Digestive 0.94 0.791 – 1.12 0.486 137 1370 all phecode
528.7 Sialolithiasis Digestive 1.13 0.964 – 1.32 0.132 163 1623 all phecode
529 Diseases and other conditions of the tongue Digestive 1.02 0.943 – 1.1 0.62 690 6878 all phecode
529.1 Glossitis Digestive 0.963 0.807 – 1.15 0.676 129 1281 all phecode
529.6 Glossodynia Digestive 0.924 0.789 – 1.08 0.33 168 1652 all phecode
530 Diseases of esophagus Digestive 0.985 0.966 – 1 0.136 17081 27931 all phecode
530.1 Esophagitis, GERD and related diseases Digestive 0.985 0.966 – 1 0.131 16572 27931 all phecode
530.11 GERD Digestive 0.983 0.964 – 1 0.0972 16143 27929 all phecode
530.12 Ulcer of esophagus Digestive 1.02 0.917 – 1.13 0.719 400 3983 all phecode
530.13 Barrett's esophagus Digestive 0.971 0.901 – 1.05 0.439 762 7584 all phecode
530.14 Reflux esophagitis Digestive 0.967 0.921 – 1.01 0.165 1900 17495 all phecode
530.15 Eosinophilic esophagitis Digestive 0.804 0.699 – 0.924 0.00208 221 2210 all phecode
530.2 Esophageal bleeding (varices/hemorrhage) Digestive 0.955 0.88 – 1.04 0.263 651 6473 all phecode
530.3 Stricture and stenosis of esophagus Digestive 1.01 0.946 – 1.09 0.712 911 8971 all phecode
530.5 Disorders of esophageal motility Digestive 1.01 0.923 – 1.1 0.854 548 5432 all phecode
530.6 Diverticulum of esophagus, acquired Digestive 1.1 0.918 – 1.32 0.296 129 1265 all phecode
530.7 Gastroesophageal laceration-hemorrhage syndrome Digestive 0.753 0.597 – 0.949 0.0164 82 812 all phecode
530.9 Heartburn Digestive 0.982 0.931 – 1.04 0.499 1519 14928 all phecode
531 Peptic ulcer (excl. esophageal) Digestive 0.998 0.954 – 1.04 0.92 2073 20617 all phecode
531.1 Hemorrhage from gastrointestinal ulcer Digestive 0.955 0.863 – 1.06 0.373 391 3883 all phecode
531.2 Gastric ulcer Digestive 0.993 0.936 – 1.05 0.824 1201 11970 all phecode
531.3 Duodenal ulcer Digestive 0.977 0.89 – 1.07 0.633 467 4640 all phecode
531.4 Peptic ulcer, site unspecified Digestive 0.935 0.87 – 1 0.065 804 8018 all phecode
531.5 Gastrojejunal ulcer Digestive 1.08 0.914 – 1.28 0.361 150 1500 all phecode
532 Dysphagia Digestive 0.983 0.954 – 1.01 0.239 5585 26852 all phecode
535 Gastritis and duodenitis Digestive 0.995 0.957 – 1.03 0.797 2799 27335 all phecode
535.1 Acute gastritis Digestive 0.997 0.938 – 1.06 0.915 1178 11750 all phecode
535.2 Atrophic gastritis Digestive 1.03 0.919 – 1.15 0.618 344 3413 all phecode
535.6 Duodenitis Digestive 0.969 0.867 – 1.08 0.58 334 3337 all phecode
535.8 Other specified gastritis Digestive 0.95 0.875 – 1.03 0.227 638 6354 all phecode
535.9 Gastritis and duodenitis, NOS Digestive 0.964 0.909 – 1.02 0.211 1255 12511 all phecode
536 Disorders of function of stomach Digestive 0.991 0.953 – 1.03 0.637 2911 27685 all phecode
536.3 Gastroparesis Digestive 1.07 0.991 – 1.16 0.0812 706 6901 all phecode
536.7
Complications of gastrostomy, colostomy and
Complications of gastrostomy, colostomy and enterostomy
 Digestive 0.979 0.885 – 1.08 0.671 407 4059 all phecode
536.8
Dyspepsia and other specified disorders of
Dyspepsia and other specified disorders of function of stomach
 Digestive 0.972 0.929 – 1.02 0.21 2150 21094 all phecode
537 Other disorders of stomach and duodenum Digestive 1.02 0.983 – 1.06 0.295 3183 30048 all phecode
537.1 Lesions of stomach and duodenum Digestive 1.08 0.932 – 1.26 0.303 173 1725 all phecode
539 Bariatric surgery Digestive 0.931 0.883 – 0.982 0.00803 1509 15074 all phecode
540 Appendiceal conditions Digestive 1.07 0.971 – 1.17 0.175 495 4948 all phecode
540.1 Appendicitis Digestive 1.06 0.962 – 1.17 0.231 425 4239 all phecode
540.11 Acute appendicitis Digestive 1.07 0.956 – 1.19 0.249 353 3511 all phecode
550 Abdominal hernia Digestive 0.994 0.968 – 1.02 0.645 6768 37731 all phecode
550.1 Inguinal hernia Digestive 0.979 0.931 – 1.03 0.395 1744 16488 all phecode
550.2 Diaphragmatic hernia Digestive 0.999 0.961 – 1.04 0.948 2817 25849 all phecode
550.3 Femoral hernia Digestive 0.884 0.74 – 1.06 0.176 131 1291 all phecode
550.4 Umbilical hernia Digestive 0.976 0.922 – 1.03 0.408 1313 13110 all phecode
550.5 Ventral hernia Digestive 0.992 0.95 – 1.04 0.719 2241 22163 all phecode
550.6 Incisional hernia Digestive 1 0.946 – 1.06 0.955 1313 13111 all phecode
555
Inflammatory bowel disease and other
Inflammatory bowel disease and other gastroenteritis and colitis
 Digestive 1.02 0.972 – 1.08 0.368 1536 15153 all phecode
555.1 Regional enteritis Digestive 1.03 0.96 – 1.1 0.427 919 9095 all phecode
555.2 Ulcerative colitis Digestive 1.02 0.949 – 1.09 0.643 937 9315 all phecode
555.21 Ulcerative colitis (chronic) Digestive 1.05 0.959 – 1.15 0.292 537 5315 all phecode
556 Ulceration of the lower GI tract Digestive 1.01 0.932 – 1.1 0.766 632 6267 all phecode
556.1 Ulceration of intestine Digestive 1.04 0.951 – 1.14 0.395 551 5451 all phecode
556.11
Angiodysplasia of intestine (without mention of
Angiodysplasia of intestine (without mention of hemorrhage)
 Digestive 1.07 0.926 – 1.23 0.361 214 2093 all phecode
557 Intestinal malabsorption (non-celiac) Digestive 0.971 0.924 – 1.02 0.254 1716 16490 all phecode
557.1 Celiac disease Digestive 0.971 0.878 – 1.07 0.57 421 4026 all phecode
558 Noninfectious gastroenteritis Digestive 1.01 0.975 – 1.05 0.572 3458 26408 all phecode
559 Ileostomy status Digestive 1.03 0.959 – 1.1 0.457 957 9565 all phecode
560 Intestinal obstruction without mention of hernia Digestive 1 0.964 – 1.04 0.915 3004 24851 all phecode
560.1 Paralytic ileus Digestive 1.03 0.976 – 1.08 0.309 1627 15714 all phecode
560.2 Impaction of intestine Digestive 0.942 0.847 – 1.05 0.267 387 3779 all phecode
560.3 Peritoneal or intestinal adhesions Digestive 0.937 0.827 – 1.06 0.31 266 2647 all phecode
560.4 Other intestinal obstruction Digestive 0.989 0.939 – 1.04 0.658 1651 16170 all phecode
561 Symptoms involving digestive system Digestive 0.965 0.926 – 1.01 0.0875 2608 21766 all phecode
562 Diverticulosis and diverticulitis Digestive 0.984 0.956 – 1.01 0.259 6295 23431 all phecode
562.1 Diverticulosis Digestive 0.986 0.958 – 1.02 0.354 6246 23383 all phecode
562.2 Diverticulitis Digestive 0.969 0.921 – 1.02 0.239 1611 15162 all phecode
564 Functional digestive disorders Digestive 0.999 0.977 – 1.02 0.915 11411 28676 all phecode
564.1 Irritable Bowel Syndrome Digestive 0.998 0.962 – 1.04 0.914 3457 22266 all phecode
564.9 Personal history of diseases of digestive system Digestive 0.988 0.951 – 1.03 0.532 3074 25861 all phecode
565 Anal and rectal conditions Digestive 1.02 0.98 – 1.05 0.393 3355 30757 all phecode
565.1 Anal and rectal polyp Digestive 0.995 0.939 – 1.05 0.859 1305 12649 all phecode
567 Peritonitis and retroperitoneal infections Digestive 0.999 0.945 – 1.06 0.96 1364 13616 all phecode
568 Other disorders of peritoneum Digestive 0.966 0.919 – 1.02 0.171 1705 17038 all phecode
568.1
Peritoneal adhesions (postoperative)
Peritoneal adhesions (postoperative) (postinfection)
 Digestive 0.944 0.891 – 1 0.0536 1247 12468 all phecode
569 Other disorders of intestine Digestive 0.999 0.975 – 1.02 0.922 8079 35231 all phecode
569.1 Toxic gastroenteritis and colitis Digestive 1.09 0.97 – 1.22 0.149 326 3260 all phecode
569.2 Gastrointestinal complications Digestive 0.959 0.907 – 1.01 0.133 1395 13933 all phecode
571 Chronic liver disease and cirrhosis Digestive 1.01 0.981 – 1.04 0.435 4610 32562 all phecode
571.5 Other chronic nonalcoholic liver disease Digestive 1.01 0.978 – 1.04 0.536 4342 32234 all phecode
571.51 Cirrhosis of liver without mention of alcohol Digestive 1 0.938 – 1.07 0.988 1018 10095 all phecode
571.6 Primary biliary cirrhosis Digestive 0.929 0.797 – 1.08 0.35 179 1790 all phecode
571.8
Liver abscess and sequelae of chronic liver
Liver abscess and sequelae of chronic liver disease
 Digestive 1.02 0.953 – 1.09 0.58 950 9498 all phecode
571.81 Portal hypertension Digestive 0.963 0.884 – 1.05 0.384 573 5730 all phecode
572 Ascites (non malignant) Digestive 0.971 0.93 – 1.01 0.179 2278 22675 all phecode
573 Other disorders of liver Digestive 1.01 0.98 – 1.04 0.55 5599 33620 all phecode
573.1 Chronic passive congestion of liver Digestive 0.876 0.727 – 1.05 0.161 136 1359 all phecode
573.2 Liver replaced by transplant Digestive 1.04 0.922 – 1.17 0.524 292 2920 all phecode
573.3 Hepatomegaly Digestive 0.942 0.856 – 1.04 0.216 470 4700 all phecode
573.4 Acute and subacute necrosis of liver Digestive 1.05 0.933 – 1.18 0.424 316 3149 all phecode
573.5 Jaundice (not of newborn) Digestive 0.979 0.915 – 1.05 0.528 958 9496 all phecode
573.6
Nonspecific elevation of levels of transaminase
Nonspecific elevation of levels of transaminase or lactic acid dehydrogenase [LDH]
 Digestive 1.01 0.971 – 1.05 0.633 2756 26470 all phecode
573.7 Abnormal results of function study of liver Digestive 1 0.962 – 1.04 0.985 3018 27774 all phecode
573.9 Abnormal serum enzyme levels Digestive 1.01 0.982 – 1.04 0.439 4679 33866 all phecode
574 Cholelithiasis and cholecystitis Digestive 0.956 0.922 – 0.992 0.0158 3177 30809 all phecode
574.1 Cholelithiasis Digestive 0.955 0.919 – 0.992 0.0168 2924 28874 all phecode
574.11 Cholelithiasis with acute cholecystitis Digestive 0.907 0.812 – 1.01 0.0871 342 3412 all phecode
574.12 Cholelithiasis with other cholecystitis Digestive 0.966 0.885 – 1.05 0.436 553 5501 all phecode
574.2 Calculus of bile duct Digestive 0.961 0.895 – 1.03 0.266 852 8503 all phecode
574.3 Cholecystitis without cholelithiasis Digestive 0.946 0.881 – 1.02 0.128 822 8181 all phecode
575 Other biliary tract disease Digestive 0.962 0.921 – 1.01 0.0834 2266 22555 all phecode
575.1 Cholangitis Digestive 1.02 0.916 – 1.14 0.706 354 3530 all phecode
575.2 Obstruction of bile duct Digestive 0.97 0.893 – 1.05 0.48 621 6201 all phecode
575.6 Cholesterolosis of gallbladder Digestive 1.04 0.899 – 1.2 0.61 207 2063 all phecode
575.7 Other disorders of gallbladder Digestive 0.931 0.871 – 0.995 0.0358 939 9382 all phecode
575.8 Other disorders of biliary tract Digestive 0.958 0.901 – 1.02 0.162 1154 11523 all phecode
575.9
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of biliary tract
 Digestive 0.968 0.852 – 1.1 0.612 260 2600 all phecode
577 Diseases of pancreas Digestive 0.956 0.916 – 0.999 0.0457 2225 22106 all phecode
577.1 Acute pancreatitis Digestive 0.93 0.877 – 0.987 0.0162 1212 12110 all phecode
577.2 Chronic pancreatitis Digestive 0.937 0.855 – 1.03 0.161 495 4950 all phecode
577.3 Cyst and pseudocyst of pancreas Digestive 0.966 0.885 – 1.05 0.442 570 5601 all phecode
578 Gastrointestinal hemorrhage Digestive 1 0.972 – 1.03 0.85 4554 37045 all phecode
578.1 Hematemesis Digestive 1.01 0.921 – 1.11 0.793 485 4842 all phecode
578.2 Blood in stool Digestive 0.986 0.948 – 1.03 0.481 2743 26554 all phecode
578.8 Hemorrhage of rectum and anus Digestive 1.02 0.979 – 1.07 0.301 2210 21750 all phecode
578.9 Hemorrhage of gastrointestinal tract Digestive 0.997 0.946 – 1.05 0.901 1562 15345 all phecode
579 Other symptoms involving abdomen and pelvis Digestive 0.989 0.959 – 1.02 0.501 4431 34209 all phecode
579.2 Splenomegaly Digestive 1.04 0.961 – 1.12 0.339 730 7262 all phecode
579.8 Nonspecific abnormal findings in stool contents Digestive 0.992 0.939 – 1.05 0.787 1410 13877 all phecode
580 Nephritis; nephrosis; renal sclerosis Genitourinary 1.01 0.961 – 1.06 0.721 1881 15516 all phecode
580.1 Glomerulonephritis Genitourinary 1.01 0.907 – 1.12 0.903 401 3992 all phecode
580.11 Proliferative glomerulonephritis Genitourinary 1.03 0.867 – 1.22 0.754 146 1440 all phecode
580.12 Non-proliferative glomerulonephritis Genitourinary 0.982 0.807 – 1.19 0.852 114 1128 all phecode
580.13 Acute glomerulonephritis, NOS Genitourinary 0.94 0.728 – 1.21 0.632 61 600 all phecode
580.14 Chronic glomerulonephritis, NOS Genitourinary 1.02 0.901 – 1.16 0.742 277 2760 all phecode
580.2
Nephrotic syndrome without mention of
Nephrotic syndrome without mention of glomerulonephritis
 Genitourinary 0.941 0.817 – 1.08 0.397 221 2193 all phecode
580.3
Nephritis and nephropathy without mention of
Nephritis and nephropathy without mention of glomerulonephritis
 Genitourinary 1.02 0.961 – 1.07 0.588 1502 11930 all phecode
580.31
Nephritis and nephropathy in diseases
Nephritis and nephropathy in diseases classified elsewhere
 Genitourinary 0.987 0.923 – 1.06 0.715 992 7228 all phecode
580.32
Nephritis and nephropathy with pathological
Nephritis and nephropathy with pathological lesion
 Genitourinary 1.05 0.967 – 1.13 0.259 683 6612 all phecode
580.4 Renal sclerosis, NOS Genitourinary 1.01 0.902 – 1.13 0.886 340 3400 all phecode
585 Renal failure Genitourinary 0.982 0.957 – 1.01 0.167 7470 32340 all phecode
585.1 Acute renal failure Genitourinary 0.987 0.955 – 1.02 0.416 4265 27230 all phecode
585.2 Renal failure NOS Genitourinary 0.973 0.905 – 1.05 0.453 832 8162 all phecode
585.3 Chronic renal failure [CKD] Genitourinary 0.985 0.956 – 1.01 0.314 5580 29470 all phecode
585.31 Renal dialysis Genitourinary 0.943 0.875 – 1.02 0.125 747 7423 all phecode
585.32 End stage renal disease Genitourinary 0.984 0.922 – 1.05 0.616 1007 9783 all phecode
585.33 Chronic Kidney Disease, Stage III Genitourinary 0.994 0.957 – 1.03 0.745 3209 21312 all phecode
585.34 Chronic Kidney Disease, Stage IV Genitourinary 0.972 0.911 – 1.04 0.404 977 9190 all phecode
585.4 Chronic kidney disease, Stage I or II Genitourinary 0.999 0.941 – 1.06 0.962 1227 11191 all phecode
586 Other disorders of the kidney and ureters Genitourinary 0.998 0.973 – 1.02 0.889 7628 34189 all phecode
586.1 Anatomical abnormatilies of kidney and ureters Genitourinary 1.06 0.946 – 1.18 0.335 349 3480 all phecode
586.11 Small kidney Genitourinary 1.07 0.922 – 1.23 0.392 210 2093 all phecode
586.12 Vesicoureteral reflux Genitourinary 1 0.84 – 1.19 0.997 136 1360 all phecode
586.2 Cyst of kidney, acquired Genitourinary 0.987 0.933 – 1.04 0.637 1381 12912 all phecode
586.3 Vascular disorders of kidney/hypertrophy Genitourinary 1.06 0.918 – 1.24 0.408 187 1862 all phecode
586.4 Stricture/obstruction of ureter Genitourinary 0.968 0.922 – 1.02 0.18 1821 17115 all phecode
587 Kidney replaced by transpant Genitourinary 0.961 0.894 – 1.03 0.274 819 8134 all phecode
588 Disorders resulting from impaired renal function Genitourinary 0.978 0.915 – 1.04 0.504 976 9389 all phecode
588.1 Renal osteodystrophy Genitourinary 1.07 0.946 – 1.2 0.294 290 2900 all phecode
588.2 Secondary hyperparathyroidism (of renal origin) Genitourinary 0.978 0.907 – 1.05 0.562 755 7275 all phecode
589 Abnormal results of function study of kidney Genitourinary 0.991 0.929 – 1.06 0.785 1007 9834 all phecode
590 Pyelonephritis Genitourinary 1.01 0.953 – 1.06 0.822 1461 14350 all phecode
591 Urinary tract infection Genitourinary 1 0.982 – 1.03 0.7 9873 32513 all phecode
592 Cystitis and urethritis Genitourinary 1.02 0.983 – 1.06 0.273 3038 24207 all phecode
592.1 Cystitis Genitourinary 1.02 0.982 – 1.06 0.285 2880 23279 all phecode
592.11 Acute cystitis Genitourinary 1.03 0.977 – 1.08 0.309 1783 16452 all phecode
592.12 Chronic cystitis Genitourinary 0.969 0.85 – 1.11 0.641 239 2343 all phecode
592.13 Chronic interstitial cystitis Genitourinary 0.999 0.905 – 1.1 0.988 431 4310 all phecode
592.2 Urethritis and urethral syndrome Genitourinary 1.1 0.946 – 1.27 0.217 210 2093 all phecode
593 Hematuria Genitourinary 1.02 0.986 – 1.05 0.28 4859 32063 all phecode
593.1 Gross hematuria Genitourinary 0.973 0.924 – 1.02 0.303 1585 14824 all phecode
593.2 Microscopic hematuria Genitourinary 1.06 0.993 – 1.13 0.0789 1049 10301 all phecode
594 Urinary calculus Genitourinary 1 0.974 – 1.03 0.986 6707 38209 all phecode
594.1 Calculus of kidney Genitourinary 1 0.976 – 1.03 0.879 6273 38051 all phecode
594.2 Calculus of lower urinary tract Genitourinary 1.04 0.933 – 1.16 0.484 366 3638 all phecode
594.3 Calculus of ureter Genitourinary 0.984 0.931 – 1.04 0.569 1361 13561 all phecode
594.8 Renal colic Genitourinary 1.04 0.934 – 1.17 0.452 356 3560 all phecode
595 Hydronephrosis Genitourinary 0.965 0.918 – 1.02 0.17 1670 16658 all phecode
596 Other disorders of bladder Genitourinary 1 0.966 – 1.04 0.902 3074 28020 all phecode
596.1 Bladder neck obstruction Genitourinary 0.934 0.842 – 1.04 0.2 400 3942 all phecode
596.5 Functional disorders of bladder Genitourinary 1.01 0.962 – 1.06 0.679 1719 17049 all phecode
597 Other disorders of urethra and urinary tract Genitourinary 0.987 0.93 – 1.05 0.656 1211 11998 all phecode
597.1 Urethral stricture (not specified as infectious) Genitourinary 0.932 0.86 – 1.01 0.0881 661 6537 all phecode
597.2 Urinary complications NEC Genitourinary 0.97 0.91 – 1.03 0.347 1049 10479 all phecode
597.8 Urethral hypermobility/ISD Genitourinary 0.935 0.806 – 1.08 0.37 189 1873 all phecode
598 Abnormal findings on examination of urine Genitourinary 1.03 0.862 – 1.23 0.743 138 1356 all phecode
598.4 Other cells and casts in urine Genitourinary 1.06 0.874 – 1.28 0.571 122 1192 all phecode
599 Other symptoms/disorders or the urinary system Genitourinary 1 0.98 – 1.02 0.968 14168 30681 all phecode
599.1 Urinary obstruction Genitourinary 0.881 0.816 – 0.95 0.000959 728 6861 all phecode
599.2 Retention of urine Genitourinary 1.01 0.977 – 1.04 0.648 5034 28305 all phecode
599.3 Dysuria Genitourinary 1.01 0.976 – 1.04 0.631 4397 27849 all phecode
599.4 Urinary incontinence Genitourinary 1.01 0.977 – 1.04 0.683 5599 26960 all phecode
599.5 Frequency of urination and polyuria Genitourinary 0.997 0.968 – 1.03 0.84 5498 28723 all phecode
599.6 Oliguria and anuria Genitourinary 0.985 0.907 – 1.07 0.723 599 5902 all phecode
599.7 Urethral discharge Genitourinary 1 0.833 – 1.21 0.96 118 1175 all phecode
599.8 Other symptoms involving urinary system Genitourinary 1.01 0.979 – 1.04 0.561 5446 27963 all phecode
599.9 Other abnormality of urination Genitourinary 0.989 0.952 – 1.03 0.557 3041 24877 all phecode
600 Hyperplasia of prostate Genitourinary 0.959 0.923 – 0.996 0.0299 4063 11364 all phecode
601 Inflammatory diseases of prostate Genitourinary 0.936 0.878 – 0.997 0.0403 1044 9665 all phecode
601.1 Prostatitis Genitourinary 0.971 0.883 – 1.07 0.545 477 4596 all phecode
601.11 Acute prostatitis Genitourinary 1.06 0.877 – 1.29 0.534 124 1200 all phecode
601.12 Chronic prostatitis Genitourinary 0.941 0.764 – 1.16 0.571 95 943 all phecode
601.3 Orchitis and epididymitis Genitourinary 0.919 0.828 – 1.02 0.113 389 3822 all phecode
601.4 Balanoposthitis Genitourinary 0.872 0.729 – 1.04 0.135 127 1224 all phecode
601.8
Other inflammatory disorders of male genital
Other inflammatory disorders of male genital organs
 Genitourinary 0.941 0.797 – 1.11 0.475 161 1591 all phecode
602 Other disorders of prostate Genitourinary 0.973 0.872 – 1.08 0.619 361 3399 all phecode
602.3 Dysplasia of prostate Genitourinary 0.955 0.755 – 1.21 0.701 77 730 all phecode
603 Other disorders of testis Genitourinary 0.909 0.825 – 1 0.0545 440 4354 all phecode
603.1 Hydrocele Genitourinary 0.847 0.752 – 0.954 0.00624 293 2882 all phecode
603.2 Spermatocele Genitourinary 0.975 0.831 – 1.14 0.759 156 1539 all phecode
604 Disorders of penis Genitourinary 0.94 0.869 – 1.02 0.12 685 6748 all phecode
604.1 Redundant prepuce and phimosis/BXO Genitourinary 1.02 0.865 – 1.21 0.794 155 1540 all phecode
604.3 Peyronie's disease Genitourinary 0.859 0.746 – 0.989 0.0344 215 2132 all phecode
605 Erectile dysfunction [ED] Genitourinary 0.976 0.94 – 1.01 0.19 3776 12700 all phecode
608 Other disorders of male genital organs Genitourinary 0.953 0.906 – 1 0.068 1645 13758 all phecode
609 Male infertility and abnormal spermatozoa Genitourinary 0.909 0.822 – 1.01 0.0645 424 4196 all phecode
609.1 Infertility, male Genitourinary 0.903 0.801 – 1.02 0.093 302 2992 all phecode
609.11 Azoospermia and oligospermia Genitourinary 0.795 0.644 – 0.982 0.0335 95 950 all phecode
609.2 Abnormal spermatozoa Genitourinary 1.02 0.861 – 1.2 0.859 154 1519 all phecode
610 Benign mammary dysplasias Genitourinary 1 0.967 – 1.04 0.896 3683 16548 all phecode
610.1 Cystic mastopathy Genitourinary 0.972 0.923 – 1.02 0.275 1633 14191 all phecode
610.2 Fibroadenosis of breast Genitourinary 0.86 0.662 – 1.12 0.26 60 600 all phecode
610.4 Benign neoplasm of breast Genitourinary 1.02 0.98 – 1.06 0.332 2837 16430 all phecode
610.8 Other specified benign mammary dysplasias Genitourinary 0.981 0.925 – 1.04 0.525 1269 12191 all phecode
611 Abnormal findings on mammogram or breast exam Genitourinary 1.02 0.991 – 1.05 0.167 6067 18690 all phecode
611.1 Abnormal mammogram Genitourinary 1.01 0.982 – 1.05 0.376 4980 16120 all phecode
611.11 Mammographic microcalcification Genitourinary 1.01 0.946 – 1.07 0.825 1122 10394 all phecode
611.3 Lump or mass in breast Genitourinary 1.02 0.98 – 1.05 0.386 3549 18572 all phecode
612
Breast conditions, congenital or relating to
Breast conditions, congenital or relating to hormones
 Genitourinary 0.984 0.923 – 1.05 0.611 1051 10425 all phecode
612.1 Galactorrhea Genitourinary 1.09 0.915 – 1.31 0.324 139 1390 all phecode
612.2 Hypertrophy of breast (Gynecomastia) Genitourinary 0.968 0.899 – 1.04 0.375 800 7962 all phecode
612.3 Congenital anomalies of breast Genitourinary 0.837 0.667 – 1.05 0.125 83 810 all phecode
613 Other nonmalignant breast conditions Genitourinary 1.01 0.978 – 1.05 0.484 3897 22072 all phecode
613.1 Inflammatory disease of breast Genitourinary 0.966 0.887 – 1.05 0.435 593 5874 all phecode
613.5 Mastodynia Genitourinary 0.995 0.945 – 1.05 0.834 1675 16203 all phecode
613.7 Other signs and symptoms in breast Genitourinary 0.992 0.925 – 1.06 0.825 883 8754 all phecode
613.8 Other specified disorders of breast Genitourinary 1.03 0.962 – 1.1 0.4 932 9248 all phecode
613.9 Breast disorder NOS Genitourinary 1 0.949 – 1.06 0.936 1465 14174 all phecode
614 Inflammatory diseases of female pelvic organs Genitourinary 1.01 0.973 – 1.04 0.65 3715 19647 all phecode
614.1
Pelvic peritoneal adhesions, female
Pelvic peritoneal adhesions, female (postoperative) (postinfection)
 Genitourinary 1.01 0.901 – 1.13 0.859 337 3370 all phecode
614.3 Pelvic inflammatory disease (PID) Genitourinary 1.07 0.975 – 1.18 0.146 478 4773 all phecode
614.31 Acute inflammatory pelvic disease Genitourinary 1.15 0.916 – 1.43 0.234 94 933 all phecode
614.32 Chronic inflammatory pelvic disease Genitourinary 1.1 0.948 – 1.29 0.201 186 1842 all phecode
614.33 Pelvic inflammatory disease, NOS Genitourinary 1.07 0.937 – 1.23 0.31 246 2460 all phecode
614.4 Inflammatory diseases of uterus, except cervix Genitourinary 1.09 0.928 – 1.28 0.296 165 1639 all phecode
614.5
Inflammatory disease of cervix, vagina, and
Inflammatory disease of cervix, vagina, and vulva
 Genitourinary 1 0.966 – 1.04 0.876 3180 19539 all phecode
614.51 Cervicitis and endocervicitis Genitourinary 1.04 0.916 – 1.18 0.557 264 2640 all phecode
614.52 Vaginitis and vulvovaginitis Genitourinary 1 0.961 – 1.04 0.959 2732 18924 all phecode
614.53 Cyst or abscess of Bartholin's gland Genitourinary 0.926 0.77 – 1.11 0.412 132 1311 all phecode
614.54 Abscess or ulceration of vulva Genitourinary 0.966 0.842 – 1.11 0.627 225 2244 all phecode
615 Endometriosis Genitourinary 0.971 0.922 – 1.02 0.278 1585 14666 all phecode
618 Genital prolapse Genitourinary 1.01 0.96 – 1.05 0.819 2079 17915 all phecode
618.1 Prolapse of vaginal walls Genitourinary 1 0.949 – 1.06 0.935 1408 13456 all phecode
618.2 Uterine/Uterovaginal prolapse Genitourinary 0.984 0.902 – 1.07 0.723 542 5390 all phecode
618.5 Prolapse of vaginal vault after hysterectomy Genitourinary 1.12 0.996 – 1.26 0.058 317 3162 all phecode
618.6 Vaginal enterocele, congenital or acquired Genitourinary 1.02 0.926 – 1.13 0.681 441 4394 all phecode
619 Noninflammatory female genital disorders Genitourinary 0.984 0.955 – 1.01 0.28 5728 18687 all phecode
619.1
Noninflammatory disorders of ovary, fallopian
Noninflammatory disorders of ovary, fallopian tube, and broad ligament
 Genitourinary 0.959 0.903 – 1.02 0.171 1233 12082 all phecode
619.2 Disorders of uterus, NEC Genitourinary 1.02 0.935 – 1.11 0.676 591 5897 all phecode
619.3 Noninflammatory disorders of cervix Genitourinary 0.941 0.856 – 1.03 0.199 483 4823 all phecode
619.4 Noninflammatory disorders of vagina Genitourinary 0.971 0.931 – 1.01 0.175 2525 18404 all phecode
619.5 Noninflammatory disorders of vulva and perineum Genitourinary 1.01 0.951 – 1.07 0.766 1189 11717 all phecode
620 Dysplasia of female genital organs Genitourinary 0.964 0.869 – 1.07 0.488 395 3950 all phecode
620.1 Dysplasia of cervix Genitourinary 0.986 0.845 – 1.15 0.864 178 1780 all phecode
621 Endometrial hyperplasia Genitourinary 0.901 0.817 – 0.994 0.037 437 4370 all phecode
622 Polyp of female genital organs Genitourinary 0.94 0.89 – 0.993 0.0263 1449 14264 all phecode
622.1 Polyp of corpus uteri Genitourinary 0.938 0.882 – 0.998 0.0423 1132 11189 all phecode
622.2 Mucous polyp of cervix Genitourinary 0.893 0.81 – 0.985 0.0241 445 4444 all phecode
623 Hypertrophy of female genital organs Genitourinary 0.948 0.883 – 1.02 0.147 824 8165 all phecode
624 Symptoms involving female genital tract Genitourinary 0.953 0.901 – 1.01 0.0986 1348 12518 all phecode
624.1 Dystrophy of female genital tract Genitourinary 1.02 0.881 – 1.17 0.826 216 2155 all phecode
624.2 Atrophy of female genital tract Genitourinary 0.898 0.697 – 1.16 0.409 64 615 all phecode
624.9 stress incontinence, female Genitourinary 0.998 0.952 – 1.05 0.937 1935 15408 all phecode
625
Pain and other symptoms associated with female
Pain and other symptoms associated with female genital organs
 Genitourinary 0.991 0.961 – 1.02 0.551 5653 17303 all phecode
625.1 Dyspareunia Genitourinary 1.03 0.969 – 1.09 0.359 1267 12474 all phecode
626
Disorders of menstruation and other abnormal
Disorders of menstruation and other abnormal bleeding from female genital tract
 Genitourinary 0.979 0.949 – 1.01 0.173 5940 15585 all phecode
626.1 Irregular menstrual cycle/bleeding Genitourinary 0.969 0.936 – 1 0.0825 4315 14604 all phecode
626.11 Absent or infrequent menstruation Genitourinary 0.968 0.908 – 1.03 0.323 1062 8531 all phecode
626.12 Excessive or frequent menstruation Genitourinary 0.964 0.92 – 1.01 0.122 2097 11991 all phecode
626.13 Irregular menstrual cycle Genitourinary 0.98 0.934 – 1.03 0.419 1957 12265 all phecode
626.14 Irregular menstrual bleeding Genitourinary 0.927 0.867 – 0.991 0.0252 970 8996 all phecode
626.15 Infertility, female, associated with anovulation Genitourinary 0.973 0.875 – 1.08 0.611 394 3789 all phecode
626.2 Dysmenorrhea Genitourinary 0.976 0.922 – 1.03 0.409 1373 9857 all phecode
626.4 Premenstrual tension syndromes Genitourinary 0.949 0.848 – 1.06 0.366 336 3308 all phecode
626.8 Infertility, female Genitourinary 1.01 0.941 – 1.09 0.723 817 6741 all phecode
627 Menopausal and postmenopausal disorders Genitourinary 0.98 0.948 – 1.01 0.248 4560 14557 all phecode
627.1 Postmenopausal bleeding Genitourinary 0.947 0.891 – 1.01 0.0809 1146 10338 all phecode
627.2 Symptomatic menopause Genitourinary 0.985 0.946 – 1.03 0.461 3017 13763 all phecode
627.21 Symptomatic artificial menopause Genitourinary 1.04 0.882 – 1.22 0.644 152 1514 all phecode
627.22
Need for Hormone replacement therapy
Need for Hormone replacement therapy (postmenopausal)
 Genitourinary 0.999 0.895 – 1.12 0.987 356 3513 all phecode
627.3 Postmenopausal atrophic vaginitis Genitourinary 0.966 0.905 – 1.03 0.306 997 9484 all phecode
627.4 Premenopausal menorrhagia Genitourinary 0.959 0.861 – 1.07 0.448 361 3580 all phecode
627.5 Premature menopause and other ovarian failure Genitourinary 0.901 0.8 – 1.01 0.0819 309 3082 all phecode
628 Ovarian cyst Genitourinary 0.977 0.931 – 1.03 0.349 1945 13838 all phecode
634 Miscarriage; stillbirth Pregnancy Complications 1.01 0.942 – 1.09 0.723 826 8047 all phecode
634.1 Missed abortion/Hydatidiform mole Pregnancy Complications 1.04 0.914 – 1.18 0.562 273 2715 all phecode
634.3 Ectopic pregnancy Pregnancy Complications 0.957 0.795 – 1.15 0.646 117 1170 all phecode
635
Hemorrhage during pregnancy; childbirth and
Hemorrhage during pregnancy; childbirth and postpartum
 Pregnancy Complications 1.07 0.982 – 1.17 0.119 563 5309 all phecode
635.2
Antepartum hemorrhage, abruptio placentae, and
Antepartum hemorrhage, abruptio placentae, and placenta previa
 Pregnancy Complications 1.06 0.947 – 1.18 0.32 370 3629 all phecode
635.3 Placenta previa and abruptio placenta Pregnancy Complications 1.03 0.913 – 1.17 0.616 288 2850 all phecode
636
Early or threatened labor; hemorrhage in early
Early or threatened labor; hemorrhage in early pregnancy
 Pregnancy Complications 0.992 0.93 – 1.06 0.808 1080 7870 all phecode
636.1 Threatened premature labor Pregnancy Complications 0.902 0.812 – 1 0.053 380 3799 all phecode
636.2 Early onset of delivery Pregnancy Complications 0.873 0.773 – 0.987 0.0297 288 2868 all phecode
636.3 Hemorrhage in early pregnancy Pregnancy Complications 1.06 0.96 – 1.18 0.24 441 4365 all phecode
636.8 Cervical incompetence Pregnancy Complications 0.896 0.705 – 1.14 0.372 77 770 all phecode
637
Short gestation; low birth weight; and fetal
Short gestation; low birth weight; and fetal growth retardation
 Pregnancy Complications 1.04 0.829 – 1.31 0.726 85 850 all phecode
642
Hypertension complicating pregnancy
Hypertension complicating pregnancy, childbirth, and the puerperium
 Pregnancy Complications 1.04 0.953 – 1.13 0.391 585 5725 all phecode
642.1 Preeclampsia and eclampsia Pregnancy Complications 1.06 0.942 – 1.19 0.333 302 3013 all phecode
643 Excessive vomiting in pregnancy Pregnancy Complications 0.948 0.833 – 1.08 0.421 252 2506 all phecode
643.1 Hyperemesis gravidarum Pregnancy Complications 1 0.826 – 1.21 0.994 119 1190 all phecode
644 Anemia during pregnancy Pregnancy Complications 0.924 0.804 – 1.06 0.26 224 2224 all phecode
646 Other complications of pregnancy NEC Pregnancy Complications 1.01 0.941 – 1.09 0.744 855 6531 all phecode
647
Infectious and parasitic complications
Infectious and parasitic complications affecting pregnancy
 Pregnancy Complications 0.941 0.815 – 1.09 0.403 211 2093 all phecode
647.1
Infections of genitourinary tract during
Infections of genitourinary tract during pregnancy
 Pregnancy Complications 0.945 0.822 – 1.09 0.423 222 2213 all phecode
647.3 Major puerperal infection Pregnancy Complications 0.979 0.765 – 1.25 0.865 65 650 all phecode
649
Other conditions or status of the mother
Other conditions or status of the mother complicating pregnancy, childbirth, or the puerperium
 Pregnancy Complications 1.02 0.963 – 1.09 0.457 1275 8010 all phecode
649.1
Diabetes or abnormal glucose tolerance
Diabetes or abnormal glucose tolerance complicating pregnancy
 Pregnancy Complications 1.04 0.956 – 1.13 0.367 649 5687 all phecode
653
Problems associated with amniotic cavity and
Problems associated with amniotic cavity and membranes
 Pregnancy Complications 1.03 0.949 – 1.13 0.44 587 5463 all phecode
654.1
Abnormality of organs and soft tissues of
Abnormality of organs and soft tissues of pelvis complicating pregnancy, childbirth, or the puerperium
 Pregnancy Complications 1.13 0.974 – 1.31 0.105 207 2055 all phecode
654.2 Rhesus isoimmunization in pregnancy Pregnancy Complications 1.14 0.982 – 1.32 0.0846 204 2040 all phecode
655
Known or suspected fetal abnormality affecting
Known or suspected fetal abnormality affecting management of mother
 Pregnancy Complications 1.05 0.999 – 1.11 0.0522 1624 10064 all phecode
655.1 Abnormality in fetal heart rate or rhythm Pregnancy Complications 1.05 0.963 – 1.14 0.272 616 5533 all phecode
656 Other perinatal conditions of fetus or newborn Pregnancy Complications 0.993 0.925 – 1.07 0.836 898 7014 all phecode
656.2 Respiratory conditions of fetus and newborn Pregnancy Complications 0.873 0.678 – 1.12 0.292 66 660 all phecode
669 Complications of labor and delivery NEC Pregnancy Complications 1.02 0.947 – 1.09 0.645 887 6802 all phecode
671
Venous/cerebrovascular complications embolism
Venous/cerebrovascular complications embolism in pregnancy and the puerperium
 Pregnancy Complications 0.939 0.822 – 1.07 0.354 236 2351 all phecode
674 Other complications of the puerperium NEC Pregnancy Complications 0.885 0.749 – 1.05 0.15 158 1580 all phecode
676
Other disorders of the breast associated with
Other disorders of the breast associated with childbirth and disorders of lactation
 Pregnancy Complications 0.993 0.851 – 1.16 0.931 184 1814 all phecode
681 Superficial cellulitis and abscess Dermatologic 0.993 0.967 – 1.02 0.617 6500 38394 all phecode
681.1 Cellulitis and abscess of fingers/toes Dermatologic 1 0.944 – 1.06 0.982 1256 11462 all phecode
681.2 Cellulitis and abscess of face/neck Dermatologic 1 0.94 – 1.07 0.933 1007 9981 all phecode
681.3 Cellulitis and abscess of arm/hand Dermatologic 0.972 0.929 – 1.02 0.209 2123 19952 all phecode
681.5 Cellulitis and abscess of leg, except foot Dermatologic 0.974 0.933 – 1.02 0.244 2252 20944 all phecode
681.6 Cellulitis and abscess of foot, toe Dermatologic 0.993 0.946 – 1.04 0.777 1820 16893 all phecode
681.7 Cellulitis and abscess of trunk Dermatologic 0.98 0.931 – 1.03 0.453 1572 15588 all phecode
686
Other local infections of skin and subcutaneous
Other local infections of skin and subcutaneous tissue
 Dermatologic 0.985 0.943 – 1.03 0.484 2257 21750 all phecode
686.1 Carbuncle and furuncle Dermatologic 1.02 0.931 – 1.11 0.722 558 5504 all phecode
686.2 Impetigo Dermatologic 0.983 0.888 – 1.09 0.744 414 4117 all phecode
686.3 Pilonidal cyst Dermatologic 0.937 0.797 – 1.1 0.43 160 1594 all phecode
686.4 Pyogenic granuloma Dermatologic 0.865 0.736 – 1.02 0.0773 158 1570 all phecode
686.5 Pyoderma Dermatologic 1.01 0.784 – 1.3 0.937 63 630 all phecode
687 Symptoms affecting skin Dermatologic 1.01 0.962 – 1.06 0.646 1690 16343 all phecode
687.1 Rash and other nonspecific skin eruption Dermatologic 1 0.976 – 1.03 0.916 7007 34623 all phecode
687.3 Changes in skin texture Dermatologic 0.967 0.875 – 1.07 0.51 415 4121 all phecode
687.4 Disturbance of skin sensation Dermatologic 1.01 0.983 – 1.04 0.477 6375 34216 all phecode
689 Disorder of skin and subcutaneous tissue NOS Dermatologic 1.01 0.986 – 1.03 0.462 9311 37335 all phecode
690 Erythematosquamous dermatosis Dermatologic 1 0.974 – 1.03 0.83 5184 31581 all phecode
690.1 Seborrheic dermatitis Dermatologic 1 0.974 – 1.03 0.831 5174 31553 all phecode
691 Congenital anomalies of skin Dermatologic 0.92 0.842 – 1 0.062 541 5337 all phecode
691.3 Congenital pigmentary anomalies of skin Dermatologic 1.01 0.775 – 1.31 0.949 62 613 all phecode
694 Dyschromia and Vitiligo Dermatologic 0.987 0.941 – 1.04 0.587 1861 17936 all phecode
694.1 Vitiligo Dermatologic 0.931 0.786 – 1.1 0.412 137 1347 all phecode
694.2 Other dyschromia Dermatologic 0.979 0.93 – 1.03 0.4 1674 16183 all phecode
694.3 Vascular disorders of skin Dermatologic 1.3 1.03 – 1.65 0.0306 82 819 all phecode
695 Erythematous conditions Dermatologic 0.948 0.917 – 0.979 0.00138 4120 30247 all phecode
695.1 Toxic erythema Dermatologic 0.853 0.677 – 1.07 0.176 70 688 all phecode
695.2 Bullous dermatoses Dermatologic 1.04 0.828 – 1.3 0.755 85 805 all phecode
695.3 Rosacea Dermatologic 0.932 0.888 – 0.979 0.00453 1816 17663 all phecode
695.4 Lupus (localized and systemic) Dermatologic 0.967 0.892 – 1.05 0.411 672 6686 all phecode
695.41 Cutaneous lupus erythematosus Dermatologic 1.01 0.883 – 1.15 0.899 247 2437 all phecode
695.42 Systemic lupus erythematosus Dermatologic 0.958 0.882 – 1.04 0.314 637 6337 all phecode
695.7 Prurigo and Lichen Dermatologic 0.939 0.864 – 1.02 0.141 605 5986 all phecode
695.8 Other specified erythematous conditions Dermatologic 0.895 0.833 – 0.962 0.0025 812 7980 all phecode
695.81 Erythema nodosum Dermatologic 0.934 0.711 – 1.23 0.62 55 550 all phecode
695.9 Unspecified erythematous condition Dermatologic 1 0.925 – 1.08 0.982 679 6756 all phecode
696 Psoriasis and related disorders Dermatologic 0.98 0.928 – 1.04 0.484 1401 13832 all phecode
696.3 Pityriasis Dermatologic 1 0.811 – 1.24 0.988 92 904 all phecode
696.4 Psoriasis Dermatologic 0.979 0.925 – 1.04 0.462 1311 12976 all phecode
696.41 Psoriasis vulgaris Dermatologic 0.971 0.915 – 1.03 0.34 1200 11867 all phecode
696.42 Psoriatic arthropathy Dermatologic 1.02 0.904 – 1.16 0.726 282 2810 all phecode
697 Sarcoidosis Dermatologic 0.978 0.875 – 1.09 0.697 333 3330 all phecode
698 Pruritus and related conditions Dermatologic 1.01 0.964 – 1.05 0.738 2254 21889 all phecode
700 Corns and callosities Dermatologic 0.975 0.92 – 1.03 0.377 1373 10894 all phecode
701
Other hypertrophic and atrophic conditions of
Other hypertrophic and atrophic conditions of skin
 Dermatologic 1.01 0.981 – 1.03 0.642 7651 38050 all phecode
701.1 Keratoderma, acquired Dermatologic 1 0.92 – 1.1 0.928 567 5524 all phecode
701.2 Scar conditions and fibrosis of skin Dermatologic 0.97 0.928 – 1.01 0.168 2184 21550 all phecode
701.3 Circumscribed scleroderma Dermatologic 1.01 0.93 – 1.11 0.755 571 5660 all phecode
701.4 Keloid scar Dermatologic 0.953 0.874 – 1.04 0.275 578 5716 all phecode
701.5 Abnormal granulation tissue Dermatologic 0.97 0.876 – 1.07 0.551 400 3982 all phecode
702
Degenerative skin conditions and other
Degenerative skin conditions and other dermatoses
 Dermatologic 1.02 0.989 – 1.04 0.253 6956 29525 all phecode
702.1 Actinic keratosis Dermatologic 0.998 0.965 – 1.03 0.889 4171 26529 all phecode
702.2 Seborrheic keratosis Dermatologic 1.02 0.994 – 1.05 0.118 5480 31552 all phecode
702.4 Degenerative skin disorders Dermatologic 1.22 0.98 – 1.51 0.0757 86 832 all phecode
703 Diseases of nail, NOS Dermatologic 0.979 0.93 – 1.03 0.413 1650 14562 all phecode
703.1 Ingrowing nail Dermatologic 0.97 0.905 – 1.04 0.379 920 8597 all phecode
704 Diseases of hair and hair follicles Dermatologic 0.971 0.936 – 1.01 0.126 3118 29542 all phecode
704.1 Alopecia Dermatologic 0.981 0.929 – 1.04 0.502 1408 13871 all phecode
704.11 Alopecia Areata Dermatologic 1.05 0.837 – 1.33 0.653 82 811 all phecode
704.12 Telogen effluvium Dermatologic 0.931 0.72 – 1.2 0.584 63 615 all phecode
704.2 Hirsutism Dermatologic 0.999 0.887 – 1.13 0.986 299 2946 all phecode
704.8
Other specified diseases of hair and hair
Other specified diseases of hair and hair follicles
 Dermatologic 0.985 0.938 – 1.04 0.562 1752 17189 all phecode
705 Disorders of sweat glands Dermatologic 0.935 0.858 – 1.02 0.128 603 6012 all phecode
705.1 Dyshidrosis Dermatologic 0.904 0.766 – 1.07 0.235 154 1540 all phecode
705.3 Hidradenitis Dermatologic 0.971 0.848 – 1.11 0.669 245 2440 all phecode
705.8 Hyperhidrosis Dermatologic 1.01 0.952 – 1.08 0.67 1112 10986 all phecode
706 Diseases of sebaceous glands Dermatologic 0.991 0.965 – 1.02 0.541 5995 39748 all phecode
706.1 Acne Dermatologic 1.01 0.971 – 1.05 0.56 2594 22570 all phecode
706.2 Sebaceous cyst Dermatologic 0.982 0.944 – 1.02 0.366 2814 26819 all phecode
706.3 Seborrhea Dermatologic 1.11 0.852 – 1.46 0.43 59 582 all phecode
706.8 Other specified diseases of sebaceous glands Dermatologic 0.983 0.934 – 1.03 0.5 1684 15289 all phecode
707 Chronic ulcer of skin Dermatologic 0.995 0.958 – 1.03 0.816 2871 26816 all phecode
707.1 Decubitus ulcer Dermatologic 1.06 0.988 – 1.14 0.102 825 8119 all phecode
707.2 Chronic ulcer of leg or foot Dermatologic 1.01 0.951 – 1.08 0.719 1108 9992 all phecode
707.3 Chronic ulcer of unspecified site Dermatologic 0.988 0.94 – 1.04 0.653 1641 16172 all phecode
709 Diffuse diseases of connective tissue Dermatologic 0.997 0.945 – 1.05 0.919 1477 14427 all phecode
709.2 Sicca syndrome Dermatologic 1.03 0.944 – 1.13 0.468 505 4986 all phecode
709.3 Systemic sclerosis Dermatologic 0.865 0.754 – 0.993 0.0393 224 2209 all phecode
709.5 Dermatomyositis Dermatologic 1 0.808 – 1.24 0.982 92 892 all phecode
709.6
Other specified diffuse diseases of connective
Other specified diffuse diseases of connective tissue
 Dermatologic 0.899 0.73 – 1.11 0.317 90 892 all phecode
709.7 Unspecified diffuse connective tissue disease Dermatologic 0.981 0.917 – 1.05 0.589 917 9089 all phecode
710
Osteomyelitis, periostitis, and other
Osteomyelitis, periostitis, and other infections involving bone
 Musculoskeletal 0.992 0.936 – 1.05 0.772 1254 12103 all phecode
710.1 Osteomyelitis Musculoskeletal 0.995 0.938 – 1.06 0.857 1203 11636 all phecode
710.11 Acute osteomyelitis Musculoskeletal 1.03 0.951 – 1.13 0.426 590 5708 all phecode
710.12 Chronic osteomyelitis Musculoskeletal 0.969 0.888 – 1.06 0.474 531 5163 all phecode
710.19 Unspecified osteomyelitis Musculoskeletal 0.986 0.928 – 1.05 0.64 1153 11149 all phecode
711 Arthropathy associated with infections Musculoskeletal 0.932 0.843 – 1.03 0.166 410 4099 all phecode
711.1 Pyogenic arthritis Musculoskeletal 0.979 0.869 – 1.1 0.731 290 2900 all phecode
712 Infective connective tissue disorders Musculoskeletal 0.948 0.816 – 1.1 0.482 178 1776 all phecode
713
Arthropathy associated with other disorders
Arthropathy associated with other disorders classified elsewhere
 Musculoskeletal 0.954 0.851 – 1.07 0.428 314 3028 all phecode
713.5
Arthropathy associated with neurological
Arthropathy associated with neurological disorders
 Musculoskeletal 1.01 0.875 – 1.17 0.875 194 1824 all phecode
714
Rheumatoid arthritis and other inflammatory
Rheumatoid arthritis and other inflammatory polyarthropathies
 Musculoskeletal 0.989 0.945 – 1.04 0.642 2086 18159 all phecode
714.1 Rheumatoid arthritis Musculoskeletal 0.989 0.94 – 1.04 0.667 1670 15087 all phecode
714.2 Juvenile rheumatoid arthritis Musculoskeletal 1.1 0.868 – 1.4 0.424 77 767 all phecode
715 Other inflammatory spondylopathies Musculoskeletal 0.961 0.906 – 1.02 0.185 1209 11967 all phecode
715.1 Sacroiliitis NEC Musculoskeletal 0.992 0.876 – 1.12 0.896 262 2611 all phecode
715.2 Ankylosing spondylitis Musculoskeletal 0.911 0.795 – 1.04 0.178 219 2182 all phecode
716 Other arthropathies Musculoskeletal 0.981 0.961 – 1 0.0793 13482 31305 all phecode
716.1 Unspecified polyarthropathy or polyarthritis Musculoskeletal 1.01 0.869 – 1.16 0.943 192 1920 all phecode
716.2 Unspecified monoarthritis Musculoskeletal 0.986 0.827 – 1.18 0.871 131 1293 all phecode
716.9 Arthropathy NOS Musculoskeletal 0.982 0.961 – 1 0.0847 13410 31294 all phecode
717 Polymyalgia Rheumatica Musculoskeletal 1.11 0.97 – 1.26 0.134 261 2565 all phecode
720 Spinal stenosis Musculoskeletal 1 0.97 – 1.04 0.865 3958 28539 all phecode
720.1 Spinal stenosis of lumbar region Musculoskeletal 1 0.963 – 1.04 0.955 2872 23656 all phecode
721 Spondylosis and allied disorders Musculoskeletal 0.993 0.965 – 1.02 0.636 5509 32391 all phecode
721.1 Spondylosis without myelopathy Musculoskeletal 0.991 0.962 – 1.02 0.548 5153 31896 all phecode
721.2 Spondylosis with myelopathy Musculoskeletal 0.996 0.929 – 1.07 0.917 867 8629 all phecode
721.8 Other allied disorders of spine Musculoskeletal 0.869 0.765 – 0.987 0.0306 262 2600 all phecode
722 Intervertebral disc disorders Musculoskeletal 0.997 0.971 – 1.02 0.846 6284 34317 all phecode
722.1 Displacement of intervertebral disc Musculoskeletal 1.02 0.98 – 1.05 0.398 3591 31411 all phecode
722.3 Schmorl's nodes Musculoskeletal 0.953 0.795 – 1.14 0.604 126 1248 all phecode
722.6 Degeneration of intervertebral disc Musculoskeletal 0.993 0.961 – 1.03 0.683 3957 30744 all phecode
722.7 Intervertebral disc disorder with myelopathy Musculoskeletal 0.988 0.902 – 1.08 0.793 515 5140 all phecode
722.8 Postlaminectomy syndrome Musculoskeletal 1.1 0.987 – 1.22 0.085 397 3968 all phecode
722.9 Other and unspecified disc disorder Musculoskeletal 0.999 0.953 – 1.05 0.954 1932 19288 all phecode
723 Other disorders of cervical region Musculoskeletal 1.02 0.953 – 1.09 0.57 952 9495 all phecode
723.1 Torticollis Musculoskeletal 1.13 0.988 – 1.29 0.0745 254 2522 all phecode
724 Other and unspecified disorders of back Musculoskeletal 1.01 0.974 – 1.04 0.723 4130 31954 all phecode
724.1 Disorders of sacrum Musculoskeletal 1.03 0.986 – 1.07 0.194 2307 21902 all phecode
724.2 Disorders of coccyx Musculoskeletal 1.02 0.925 – 1.13 0.658 426 4215 all phecode
724.8 Other symptoms referable to back Musculoskeletal 0.958 0.896 – 1.02 0.204 931 9295 all phecode
724.9 Other unspecified back disorders Musculoskeletal 1.01 0.959 – 1.07 0.642 1412 14087 all phecode
726 Peripheral enthesopathies and allied syndromes Musculoskeletal 0.997 0.974 – 1.02 0.78 9917 30176 all phecode
726.1 Enthesopathy Musculoskeletal 1 0.978 – 1.03 0.788 7507 30106 all phecode
726.2 Synoviopathy Musculoskeletal 0.937 0.879 – 1 0.0491 1015 9987 all phecode
726.3 Bursitis Musculoskeletal 0.963 0.917 – 1.01 0.125 1829 16722 all phecode
726.4 Calcaneal spur; Exostosis NOS Musculoskeletal 0.961 0.906 – 1.02 0.194 1193 11485 all phecode
727 Other disorders of synovium, tendon, and bursa Musculoskeletal 0.991 0.966 – 1.02 0.486 7425 30105 all phecode
727.1 Synovitis and tenosynovitis Musculoskeletal 1 0.963 – 1.04 0.994 3092 24998 all phecode
727.2 Bursitis disorders Musculoskeletal 0.934 0.844 – 1.03 0.182 419 4112 all phecode
727.4 Ganglion and cyst of synovium, tendon, and bursa Musculoskeletal 0.992 0.938 – 1.05 0.764 1400 13621 all phecode
727.5 Rupture of synovium Musculoskeletal 0.983 0.894 – 1.08 0.728 480 4672 all phecode
727.6 Rupture of tendon, nontraumatic Musculoskeletal 0.993 0.952 – 1.04 0.757 2461 21948 all phecode
727.7 Contracture of tendon (sheath) Musculoskeletal 1.01 0.931 – 1.1 0.765 591 5893 all phecode
727.8 Plica syndrome Musculoskeletal 1.04 0.867 – 1.26 0.656 130 1264 all phecode
728 Disorders of muscle, ligament, and fascia Musculoskeletal 0.994 0.963 – 1.03 0.725 4546 29473 all phecode
728.1 Muscular calcification and ossification Musculoskeletal 1.01 0.81 – 1.26 0.927 85 843 all phecode
728.2 Laxity of ligament or hypermobility syndrome Musculoskeletal 1.02 0.902 – 1.15 0.782 297 2949 all phecode
728.7 Fasciitis Musculoskeletal 0.986 0.948 – 1.03 0.485 2814 23463 all phecode
728.71
Contracture of palmar fascia [Dupuytren's
Contracture of palmar fascia [Dupuytren's disease]
 Musculoskeletal 0.984 0.891 – 1.09 0.746 419 4138 all phecode
729 Other disorders of soft tissues Musculoskeletal 0.995 0.961 – 1.03 0.771 3642 27471 all phecode
729.1 Rheumatism, unspecified and fibrositis Musculoskeletal 0.903 0.713 – 1.14 0.398 74 726 all phecode
729.3 Panniculitis Musculoskeletal 1.01 0.836 – 1.23 0.903 119 1174 all phecode
729.7 Nontraumatic compartment syndrome Musculoskeletal 0.901 0.707 – 1.15 0.4 67 664 all phecode
731
Osteitis deformans and osteopathies associated
Osteitis deformans and osteopathies associated with other disorders classified elsewhere
 Musculoskeletal 0.917 0.795 – 1.06 0.233 210 2091 all phecode
732 Osteochondropathies Musculoskeletal 1.02 0.916 – 1.14 0.71 361 3604 all phecode
732.1 Juvenile osteochondrosis Musculoskeletal 0.967 0.834 – 1.12 0.654 198 1969 all phecode
732.7 Osteochondritis dissecans Musculoskeletal 1.04 0.841 – 1.3 0.693 90 882 all phecode
733 Other disorders of bone and cartilage Musculoskeletal 1 0.971 – 1.04 0.875 4543 26941 all phecode
733.2 Cyst of bone Musculoskeletal 1.08 0.923 – 1.25 0.347 190 1900 all phecode
733.4 Aseptic necrosis of bone Musculoskeletal 0.978 0.894 – 1.07 0.631 518 5160 all phecode
733.6 Costochondritis Musculoskeletal 1 0.897 – 1.12 0.995 357 3562 all phecode
733.8 Malunion and nonunion of fracture Musculoskeletal 0.944 0.88 – 1.01 0.113 822 8205 all phecode
733.9 Chondromalacia Musculoskeletal 1.13 0.916 – 1.39 0.258 96 960 all phecode
735 Acquired foot deformities Musculoskeletal 0.977 0.943 – 1.01 0.2 3417 29622 all phecode
735.1 Flat foot Musculoskeletal 1.01 0.926 – 1.1 0.87 620 6092 all phecode
735.2 Acquired toe deformities Musculoskeletal 1.02 0.968 – 1.09 0.403 1323 11983 all phecode
735.21 Hammer toe (acquired) Musculoskeletal 0.98 0.912 – 1.05 0.575 825 7494 all phecode
735.23 Hallux rigidus Musculoskeletal 1.1 0.991 – 1.22 0.0731 405 4005 all phecode
735.3 Hallux valgus (Bunion) Musculoskeletal 0.953 0.902 – 1.01 0.0773 1470 14295 all phecode
736 Other acquired deformities of limbs Musculoskeletal 0.966 0.929 – 1.01 0.0884 2763 26555 all phecode
736.1 Acquired deformities of forearm Musculoskeletal 0.907 0.74 – 1.11 0.347 104 1033 all phecode
736.2 Acquired deformities of finger Musculoskeletal 1.11 0.962 – 1.28 0.151 215 2142 all phecode
736.3 Acquired deformities of hip Musculoskeletal 0.943 0.723 – 1.23 0.664 60 590 all phecode
736.4 Genu valgum or varum (acquired) Musculoskeletal 0.95 0.848 – 1.06 0.37 325 3247 all phecode
736.5 Acquired deformities of knee Musculoskeletal 0.949 0.833 – 1.08 0.43 246 2460 all phecode
736.6 Unequal leg length (acquired) Musculoskeletal 0.961 0.861 – 1.07 0.476 339 3365 all phecode
737 Curvature of spine Musculoskeletal 0.952 0.904 – 1 0.067 1566 15543 all phecode
737.1 Kyphosis (acquired) Musculoskeletal 0.987 0.9 – 1.08 0.784 479 4748 all phecode
737.2 Lordosis (acquired) Musculoskeletal 1.03 0.813 – 1.29 0.832 70 700 all phecode
737.3 Kyphoscoliosis and scoliosis Musculoskeletal 0.949 0.895 – 1.01 0.086 1203 11982 all phecode
738 Other acquired musculoskeletal deformity Musculoskeletal 0.979 0.939 – 1.02 0.319 2443 24187 all phecode
738.4 Acquired spondylolisthesis Musculoskeletal 0.995 0.933 – 1.06 0.87 1057 10542 all phecode
739 Contracture of joint Musculoskeletal 0.92 0.847 – 1 0.0503 621 6207 all phecode
740 Osteoarthrosis Musculoskeletal 0.993 0.973 – 1.01 0.494 16169 30268 all phecode
740.1 Osteoarthritis; localized Musculoskeletal 0.997 0.97 – 1.02 0.805 7005 27422 all phecode
740.11 Osteoarthrosis, localized, primary Musculoskeletal 0.998 0.97 – 1.03 0.881 6176 26155 all phecode
740.12 Osteoarthrosis, localized, secondary Musculoskeletal 0.951 0.88 – 1.03 0.205 713 7116 all phecode
740.2 Osteoarthrosis, generalized Musculoskeletal 1.02 0.968 – 1.08 0.448 1609 12092 all phecode
740.3
Osteoarthrosis involving more than one site
Osteoarthrosis involving more than one site, but not specified as generalized
 Musculoskeletal 0.982 0.883 – 1.09 0.734 373 3586 all phecode
740.9 Osteoarthrosis NOS Musculoskeletal 0.992 0.971 – 1.01 0.416 15497 30141 all phecode
741 Symptoms and disorders of the joints Musculoskeletal 1.01 0.982 – 1.03 0.643 8555 35884 all phecode
741.1 Ankylosis of joint Musculoskeletal 1.07 0.934 – 1.22 0.336 245 2445 all phecode
741.2 Stiffness of joint Musculoskeletal 1.02 0.961 – 1.08 0.516 1268 12594 all phecode
741.3 Difficulty in walking Musculoskeletal 1 0.96 – 1.04 0.989 2558 23116 all phecode
741.4 Joint effusions Musculoskeletal 1.04 0.996 – 1.08 0.08 2493 24199 all phecode
741.5 Hemarthrosis Musculoskeletal 1.25 1.02 – 1.54 0.0352 94 937 all phecode
741.6 Villonodular synovitis Musculoskeletal 1.05 0.821 – 1.35 0.693 68 666 all phecode
742 Derangement of joint, non-traumatic Musculoskeletal 1.01 0.975 – 1.04 0.686 4404 33771 all phecode
742.1 Loose body in joint Musculoskeletal 1.2 1.01 – 1.42 0.0357 156 1554 all phecode
742.2
Pathological, developmental or recurrent
Pathological, developmental or recurrent dislocation
 Musculoskeletal 0.974 0.865 – 1.1 0.662 280 2792 all phecode
742.8 Articular cartilage disorder Musculoskeletal 1.06 0.93 – 1.21 0.383 245 2450 all phecode
742.9 Other derangement of joint Musculoskeletal 1 0.971 – 1.04 0.828 4107 32972 all phecode
743
Osteoporosis, osteopenia and pathological
Osteoporosis, osteopenia and pathological fracture
 Musculoskeletal 0.998 0.974 – 1.02 0.869 9223 36921 all phecode
743.1 Osteoporosis Musculoskeletal 0.987 0.952 – 1.02 0.493 3712 19477 all phecode
743.11 Osteoporosis NOS Musculoskeletal 0.987 0.952 – 1.02 0.487 3657 19276 all phecode
743.12 Senile osteoporosis Musculoskeletal 1.04 0.956 – 1.12 0.392 703 5804 all phecode
743.13 Other specified osteoporosis Musculoskeletal 1.02 0.913 – 1.15 0.678 321 3141 all phecode
743.2 Pathologic fracture Musculoskeletal 1.03 0.972 – 1.1 0.283 1112 10563 all phecode
743.21 Pathologic fracture of vertebrae Musculoskeletal 1.05 0.959 – 1.16 0.281 475 4629 all phecode
743.22 Pathologic fracture of femur Musculoskeletal 0.989 0.83 – 1.18 0.902 143 1391 all phecode
743.4 Stress fracture Musculoskeletal 1.09 0.983 – 1.21 0.101 407 4046 all phecode
743.9
Osteopenia or other disorder of bone and
Osteopenia or other disorder of bone and cartilage
 Musculoskeletal 1 0.976 – 1.03 0.883 6970 35237 all phecode
745 Pain in joint Musculoskeletal 0.997 0.979 – 1.02 0.766 19848 26918 all phecode
747 Cardiac and circulatory congenital anomalies Congenital Anomalies 1 0.959 – 1.05 0.933 2236 22256 all phecode
747.1 Cardiac congenital anomalies Congenital Anomalies 1 0.954 – 1.05 0.927 1767 17598 all phecode
747.11 Cardiac shunt/ heart septal defect Congenital Anomalies 0.962 0.887 – 1.04 0.346 650 6497 all phecode
747.12 Valvular heart disease/ heart chambers Congenital Anomalies 1.01 0.939 – 1.09 0.738 751 7480 all phecode
747.13 Congenital anomalies of great vessels Congenital Anomalies 1.04 0.936 – 1.15 0.495 410 4090 all phecode
747.2
Congenital anomalies of peripheral vascular
Congenital anomalies of peripheral vascular system
 Congenital Anomalies 1 0.913 – 1.1 0.995 501 5010 all phecode
748 Anomalies of respiratory system, congenital Congenital Anomalies 0.936 0.768 – 1.14 0.512 111 1110 all phecode
749 Congenital anomalies of face and neck Congenital Anomalies 0.942 0.864 – 1.03 0.182 555 5549 all phecode
749.1 Cleft palate Congenital Anomalies 1.12 0.899 – 1.38 0.32 97 970 all phecode
749.2 Congenital anomalies of skull and face bones Congenital Anomalies 1.05 0.86 – 1.27 0.651 105 1041 all phecode
750 Digestive congenital anomalies Congenital Anomalies 0.984 0.919 – 1.05 0.641 893 8919 all phecode
750.1 Upper gastrointestinal congenital anomalies Congenital Anomalies 1.05 0.941 – 1.17 0.393 366 3655 all phecode
750.11 Esophageal atresia/tracheoesophageal fistula Congenital Anomalies 1.1 0.913 – 1.33 0.314 119 1185 all phecode
750.13 Congenital anomalies of mouth/tongue Congenital Anomalies 0.899 0.735 – 1.1 0.299 99 982 all phecode
750.14 Congenital anomalies of esophagus Congenital Anomalies 1.17 0.976 – 1.4 0.0901 134 1332 all phecode
750.15 Congenital anomalies of stomach Congenital Anomalies 1.08 0.83 – 1.41 0.564 60 593 all phecode
750.2 Lower gastrointestinal congenital anomalies Congenital Anomalies 0.942 0.862 – 1.03 0.182 531 5300 all phecode
750.21 Congenital anomalies of intestine Congenital Anomalies 0.985 0.878 – 1.11 0.797 313 3129 all phecode
750.22
Congenital anomaly of gallbladder, bile ducts
Congenital anomaly of gallbladder, bile ducts, liver, pancreas
 Congenital Anomalies 0.879 0.767 – 1.01 0.0628 222 2214 all phecode
751 Genitourinary congenital anomalies Congenital Anomalies 0.98 0.936 – 1.03 0.392 2008 19975 all phecode
751.1 Congenital anomalies of genital organs Congenital Anomalies 1.06 0.972 – 1.16 0.19 574 5740 all phecode
751.11 Congenital anomalies of female genital organs Congenital Anomalies 1.08 0.969 – 1.2 0.169 384 3840 all phecode
751.12 Congenital anomalies of male genital organs Congenital Anomalies 1.03 0.869 – 1.22 0.749 153 1527 all phecode
751.2 Congenital anomalies of urinary system Congenital Anomalies 0.956 0.905 – 1.01 0.11 1379 13704 all phecode
751.21 Cystic kidney disease Congenital Anomalies 0.943 0.883 – 1.01 0.0831 976 9685 all phecode
751.22 Other specified congenital anomalies of kidney Congenital Anomalies 1.01 0.893 – 1.13 0.932 294 2927 all phecode
751.3 Obstructive genitourinary defect Congenital Anomalies 1.02 0.88 – 1.19 0.757 182 1809 all phecode
752 Nervous system congenital anomalies Congenital Anomalies 0.976 0.918 – 1.04 0.444 1133 11313 all phecode
752.1 Neural tube defects Congenital Anomalies 0.967 0.903 – 1.04 0.333 923 9209 all phecode
752.11 Spina bifida Congenital Anomalies 1.01 0.87 – 1.18 0.865 176 1760 all phecode
752.2
Other specified congenital anomalies of nervous
Other specified congenital anomalies of nervous system
 Congenital Anomalies 1.02 0.89 – 1.16 0.8 232 2320 all phecode
753 Congenital anomalies of the eye Congenital Anomalies 1.06 0.916 – 1.22 0.456 207 2051 all phecode
753.1 Congenital cataract and lens anomalies Congenital Anomalies 1.21 0.93 – 1.57 0.157 58 580 all phecode
753.2 Congenital anomalies of posterior segment of eye Congenital Anomalies 1.08 0.818 – 1.42 0.592 56 546 all phecode
754 Congenital musculoskeletal deformities of spine Congenital Anomalies 0.959 0.903 – 1.02 0.164 1216 12116 all phecode
754.1 Lumbosacral spondylolysis, congenital Congenital Anomalies 0.989 0.823 – 1.19 0.902 135 1333 all phecode
754.2 Spondylolisthesis, congenital Congenital Anomalies 0.953 0.873 – 1.04 0.283 558 5570 all phecode
755 Congenital anomalies of limbs Congenital Anomalies 0.983 0.911 – 1.06 0.663 747 7458 all phecode
755.1 Congenital deformities of feet Congenital Anomalies 0.987 0.887 – 1.1 0.812 368 3663 all phecode
755.4
Congenital anomalies of upper limb, including
Congenital anomalies of upper limb, including shoulder girdle
 Congenital Anomalies 0.958 0.747 – 1.23 0.735 74 740 all phecode
755.6
Other congenital anomalies of lower limb
Other congenital anomalies of lower limb, including pelvic girdle
 Congenital Anomalies 0.97 0.864 – 1.09 0.613 321 3205 all phecode
755.61 Congenital hip dysplasia and deformity Congenital Anomalies 1.03 0.888 – 1.21 0.663 185 1847 all phecode
756 Other congenital musculoskeletal anomalies Congenital Anomalies 0.999 0.944 – 1.06 0.959 1358 13579 all phecode
756.1 Congenital anomalies of abdominal wall; diaphram Congenital Anomalies 0.971 0.753 – 1.25 0.818 68 680 all phecode
756.2
Pectus and other congenital anomalies of
Pectus and other congenital anomalies of ribs/sternum
 Congenital Anomalies 1.1 0.856 – 1.4 0.465 71 694 all phecode
756.3
Congenital anomalies of muscle, tendon, fascia
Congenital anomalies of muscle, tendon, fascia, and connective tissue
 Congenital Anomalies 1.01 0.906 – 1.13 0.84 335 3346 all phecode
756.5 Congenital osteodystrophies Congenital Anomalies 1.01 0.949 – 1.08 0.681 1003 10014 all phecode
757 Congenital anomalies of the integument Congenital Anomalies 1.04 0.938 – 1.15 0.463 401 4001 all phecode
758 Chromosomal anomalies and genetic disorders Congenital Anomalies 0.967 0.831 – 1.13 0.666 185 1845 all phecode
758.1 Chromosomal anomalies Congenital Anomalies 0.976 0.819 – 1.16 0.782 135 1349 all phecode
759 Other and unspecified congenital anomalies Congenital Anomalies 0.969 0.889 – 1.06 0.481 557 5566 all phecode
759.1 Anomalies of endocrine glands, congenital Congenital Anomalies 0.908 0.714 – 1.15 0.43 71 710 all phecode
760 Back pain Symptoms 1 0.985 – 1.02 0.705 16037 30719 all phecode
761 Cervicalgia Symptoms 0.999 0.973 – 1.03 0.965 6528 39755 all phecode
763
Thoracic or lumbosacral neuritis or
Thoracic or lumbosacral neuritis or radiculitis, unspecified
 Symptoms 0.994 0.96 – 1.03 0.722 3657 32599 all phecode
764 Sciatica Symptoms 1.01 0.974 – 1.04 0.635 3542 32015 all phecode
765 Cervical radiculitis Symptoms 0.994 0.947 – 1.04 0.807 1799 17851 all phecode
766 Neuralgia, neuritis, and radiculitis NOS Symptoms 0.978 0.95 – 1.01 0.14 5124 37132 all phecode
767 Cervicocranial/Cervicobrachial syndrome Symptoms 1.07 0.886 – 1.29 0.491 117 1168 all phecode
769 Nonallopathic lesions NEC Symptoms 1.02 0.957 – 1.08 0.562 1131 11220 all phecode
770 Myalgia and myositis unspecified Symptoms 1.01 0.984 – 1.04 0.393 5533 34303 all phecode
771 Musculoskeletal symptoms referable to limbs Symptoms 0.974 0.945 – 1 0.0868 4799 35575 all phecode
771.1 Swelling of limb Symptoms 0.965 0.938 – 0.992 0.0124 5743 35539 all phecode
771.2 Cramp of limb Symptoms 1.04 0.976 – 1.11 0.233 1079 10568 all phecode
772 Symptoms of the muscles Symptoms 0.969 0.926 – 1.01 0.174 2042 20221 all phecode
772.1 Muscular wasting and disuse atrophy Symptoms 1 0.906 – 1.11 0.976 422 4199 all phecode
772.2 Spasm of muscle Symptoms 0.982 0.94 – 1.03 0.404 2299 22726 all phecode
772.3 Muscle weakness Symptoms 1.01 0.971 – 1.05 0.651 2949 28064 all phecode
772.4 Rhabdomyolysis Symptoms 1.07 0.908 – 1.26 0.415 159 1572 all phecode
772.6 Facial weakness Symptoms 1.01 0.923 – 1.12 0.761 478 4742 all phecode
780 Hypothermia/Chills Symptoms 1.02 0.921 – 1.12 0.758 453 4514 all phecode
781
Symptoms involving nervous and musculoskeletal
Symptoms involving nervous and musculoskeletal systems
 Symptoms 0.969 0.932 – 1.01 0.11 2822 26225 all phecode
781.1 Loss of height Symptoms 1.03 0.865 – 1.24 0.712 130 1269 all phecode
781.2 Abnormal posture Symptoms 0.969 0.748 – 1.25 0.809 57 567 all phecode
782.3 Edema Symptoms 0.987 0.96 – 1.02 0.375 5874 36788 all phecode
782.6 Pallor and flushing Symptoms 1.04 0.975 – 1.12 0.218 927 9252 all phecode
783 Fever of unknown origin Symptoms 1.01 0.983 – 1.04 0.464 5733 40720 all phecode
783.1 Postprocedural fever Symptoms 0.915 0.813 – 1.03 0.139 300 2992 all phecode
785 Abdominal pain Symptoms 0.988 0.969 – 1.01 0.216 16458 30297 all phecode
788 Syncope and collapse Symptoms 1.02 0.987 – 1.06 0.23 3851 35832 all phecode
789 Nausea and vomiting Symptoms 1.01 0.987 – 1.03 0.41 10568 36098 all phecode
789.1 Persistent vomiting Symptoms 0.983 0.914 – 1.06 0.637 798 7924 all phecode
790 Nonspecific findings on examination of blood Symptoms 1 0.961 – 1.05 0.89 2363 22690 all phecode
790.1 Elevated sedimentation rate Symptoms 1.12 0.977 – 1.28 0.103 236 2322 all phecode
790.6 Other abnormal blood chemistry Symptoms 1.01 0.984 – 1.03 0.473 7539 37788 all phecode
790.8 Elevated C-reactive protein (CRP) Symptoms 1.03 0.915 – 1.15 0.64 309 3075 all phecode
790.9 Abnormal arterial blood gases Symptoms 0.897 0.765 – 1.05 0.181 155 1521 all phecode
791 Gangrene Symptoms 0.996 0.886 – 1.12 0.947 313 3115 all phecode
792
Abnormal Papanicolaou smear of cervix and
Abnormal Papanicolaou smear of cervix and cervical HPV
 Genitourinary 0.979 0.94 – 1.02 0.296 2820 14872 all phecode
792.1
Papanicolaou smear of cervix or vagina with
Papanicolaou smear of cervix or vagina with atypical squamous cells
 Genitourinary 0.981 0.921 – 1.04 0.541 1100 9861 all phecode
794
Abnormal results of other function studies
Abnormal results of other function studies (bladder, pancreas, placenta, spleen, etc)
 Symptoms 1.05 0.955 – 1.15 0.324 515 5133 all phecode
795
Other and nonspecific abnormal cytological
Other and nonspecific abnormal cytological, histological and immunological findings
 Symptoms 0.971 0.928 – 1.01 0.186 2182 20242 all phecode
795.8 Abnormal tumor markers Symptoms 0.989 0.942 – 1.04 0.676 1745 15551 all phecode
795.81 Elevated carcinoembryonic antigen [CEA] Symptoms 1.03 0.795 – 1.34 0.809 61 605 all phecode
795.82 Elevated cancer antigen 125 [CA 125] Symptoms 0.993 0.857 – 1.15 0.927 201 2000 all phecode
796 Elevated prostate specific antigen [PSA] Genitourinary 0.973 0.928 – 1.02 0.257 2125 9930 all phecode
797 Shock Symptoms 1.02 0.937 – 1.11 0.677 605 6050 all phecode
797.1 Cardiogenic shock Symptoms 1.02 0.893 – 1.17 0.765 242 2420 all phecode
798 Malaise and fatigue Symptoms 1.02 0.994 – 1.04 0.152 11539 35196 all phecode
798.1 Chronic fatigue syndrome Symptoms 1 0.952 – 1.05 0.991 1823 17795 all phecode
800 Fracture of lower limb Injuries & Poisonings 0.997 0.956 – 1.04 0.893 2344 22951 all phecode
800.1 Fracture of neck of femur Injuries & Poisonings 0.96 0.877 – 1.05 0.368 512 4961 all phecode
800.2 Fracture of unspecified part of femur Injuries & Poisonings 0.99 0.915 – 1.07 0.798 670 6582 all phecode
800.3 Fracture of tibia and fibula Injuries & Poisonings 0.989 0.924 – 1.06 0.761 898 8966 all phecode
800.4 Fracture of patella Injuries & Poisonings 1 0.899 – 1.12 0.98 346 3456 all phecode
801 Fracture of ankle and foot Injuries & Poisonings 1 0.961 – 1.05 0.89 2358 22645 all phecode
801.1 Fracture of foot Injuries & Poisonings 1.01 0.951 – 1.07 0.724 1120 11178 all phecode
802 Fracture of pelvis Injuries & Poisonings 1.05 0.941 – 1.16 0.403 380 3765 all phecode
803 Fracture of upper limb Injuries & Poisonings 0.993 0.948 – 1.04 0.76 2051 20360 all phecode
803.1 Fracture of humerus Injuries & Poisonings 1.03 0.951 – 1.11 0.5 734 7322 all phecode
803.2 Fracture of radius and ulna Injuries & Poisonings 0.977 0.918 – 1.04 0.455 1112 11075 all phecode
803.21 Colles' fracture Injuries & Poisonings 1 0.886 – 1.13 0.999 291 2904 all phecode
803.3 Fracture of clavicle or scapula Injuries & Poisonings 0.947 0.866 – 1.04 0.237 514 5140 all phecode
804 Fracture of hand or wrist Injuries & Poisonings 1.02 0.964 – 1.07 0.568 1628 16042 all phecode
805
Fracture of vertebral column without mention of
Fracture of vertebral column without mention of spinal cord injury
 Injuries & Poisonings 1.02 0.96 – 1.07 0.588 1336 13242 all phecode
807 Fracture of ribs Injuries & Poisonings 1.01 0.932 – 1.09 0.829 683 6815 all phecode
809 Fracture of unspecified bones Injuries & Poisonings 0.993 0.956 – 1.03 0.726 2941 28633 all phecode
816 Cerebral laceration and contusion Injuries & Poisonings 0.749 0.568 – 0.988 0.0408 54 531 all phecode
817 Concussion Injuries & Poisonings 1.02 0.959 – 1.09 0.481 1018 10149 all phecode
818 Intracranial hemorrhage (injury) Injuries & Poisonings 0.956 0.852 – 1.07 0.44 311 3104 all phecode
818.1 Subdural hemorrhage (injury) Injuries & Poisonings 0.91 0.737 – 1.12 0.382 90 895 all phecode
818.2 Subarachnoid hemorrhage (injury) Injuries & Poisonings 1.08 0.879 – 1.32 0.473 97 970 all phecode
819
Skull and face fracture and other intercranial
Skull and face fracture and other intercranial injury
 Injuries & Poisonings 0.982 0.94 – 1.03 0.403 2287 22671 all phecode
830 Dislocation Injuries & Poisonings 1.01 0.981 – 1.05 0.415 3862 34720 all phecode
835 Internal derangement of knee Injuries & Poisonings 1.01 0.965 – 1.05 0.698 2231 21628 all phecode
836 Traumatic arthropathy Injuries & Poisonings 0.964 0.879 – 1.06 0.433 496 4954 all phecode
840 Sprains and strains Injuries & Poisonings 0.995 0.971 – 1.02 0.715 7838 37998 all phecode
840.1 Muscle/tendon sprain Injuries & Poisonings 1.02 0.931 – 1.11 0.705 537 5356 all phecode
840.2 Rotator cuff (capsule) sprain Injuries & Poisonings 0.981 0.933 – 1.03 0.469 1640 16263 all phecode
840.3 Joint/ligament sprain Injuries & Poisonings 0.991 0.953 – 1.03 0.652 2875 24879 all phecode
841 Sprains and strains of back and neck Injuries & Poisonings 0.968 0.919 – 1.02 0.218 1583 15592 all phecode
842 Other sprains and strains Injuries & Poisonings 1.01 0.954 – 1.07 0.769 1407 13924 all phecode
850 Hemorrhage or hematoma complicating a procedure Injuries & Poisonings 0.965 0.922 – 1.01 0.12 2072 20649 all phecode
851
Complications of transplants and reattached
Complications of transplants and reattached limbs
 Injuries & Poisonings 0.972 0.936 – 1.01 0.134 2982 27545 all phecode
853 Complication of colostomy or enterostomy Injuries & Poisonings 1.04 0.942 – 1.15 0.44 460 4600 all phecode
854
Complications of cardiac/vascular device
Complications of cardiac/vascular device, implant, and graft
 Injuries & Poisonings 1.03 0.983 – 1.08 0.21 1985 19675 all phecode
855
Complication of nervous system device, implant
Complication of nervous system device, implant, and graft
 Injuries & Poisonings 1.03 0.909 – 1.17 0.62 264 2640 all phecode
856
Vascular complications of surgery and medical
Vascular complications of surgery and medical procedures
 Injuries & Poisonings 0.996 0.883 – 1.12 0.948 293 2929 all phecode
857
Mechanical complication of unspecified
Mechanical complication of unspecified genitourinary device, implant, and graft
 Injuries & Poisonings 0.983 0.928 – 1.04 0.549 1310 13087 all phecode
858 Complication of internal orthopedic device Injuries & Poisonings 0.982 0.94 – 1.03 0.416 2213 21944 all phecode
859
Complication due to other implant and internal
Complication due to other implant and internal device
 Injuries & Poisonings 0.978 0.935 – 1.02 0.333 2110 21070 all phecode
860 Bone marrow or stem cell transplant Neoplasms 0.988 0.842 – 1.16 0.88 166 1660 all phecode
870 Open wounds of head; neck; and trunk Injuries & Poisonings 0.982 0.951 – 1.01 0.263 4117 36734 all phecode
870.1 Open wound or laceration of eye or eyelid Injuries & Poisonings 0.967 0.838 – 1.12 0.647 204 2026 all phecode
870.2 Open wound of ear Injuries & Poisonings 1.02 0.857 – 1.2 0.859 144 1437 all phecode
870.3 Other open wound of head and face Injuries & Poisonings 0.954 0.902 – 1.01 0.0978 1346 13301 all phecode
870.4 Open wound of nose and sinus Injuries & Poisonings 1.02 0.886 – 1.18 0.764 207 2057 all phecode
870.5 Open wound of lip and mouth Injuries & Poisonings 1.01 0.889 – 1.14 0.915 275 2724 all phecode
870.6 Open wound of neck Injuries & Poisonings 0.966 0.842 – 1.11 0.629 214 2128 all phecode
870.8 Open wound of genital organs Injuries & Poisonings 1.06 0.892 – 1.25 0.521 144 1440 all phecode
871 Open wounds of extremities Injuries & Poisonings 1.01 0.972 – 1.04 0.705 3530 32903 all phecode
871.1 Open wound of hand except finger(s) Injuries & Poisonings 0.997 0.913 – 1.09 0.938 572 5701 all phecode
871.2 Open wound of finger(s) Injuries & Poisonings 1.01 0.947 – 1.08 0.733 984 9772 all phecode
871.3 Open wound of foot except toe(s) alone Injuries & Poisonings 0.991 0.903 – 1.09 0.849 490 4843 all phecode
871.4 Open wound of toe(s) Injuries & Poisonings 1.08 0.957 – 1.21 0.222 295 2921 all phecode
872 Traumatic amputation Injuries & Poisonings 1.04 0.949 – 1.13 0.434 551 5477 all phecode
874 Complication of amputation stump Injuries & Poisonings 0.971 0.831 – 1.14 0.714 170 1697 all phecode
875 Non-healing surgical wound Injuries & Poisonings 0.95 0.871 – 1.04 0.254 572 5720 all phecode
876
Posttraumatic wound infection not elsewhere
Posttraumatic wound infection not elsewhere classified
 Injuries & Poisonings 1 0.93 – 1.08 0.999 802 8003 all phecode
907 Injuries to the nervous system Injuries & Poisonings 1.11 1.04 – 1.18 0.00209 1010 10096 all phecode
910 Superficial injury, infected Injuries & Poisonings 0.971 0.801 – 1.18 0.763 119 1161 all phecode
911 Blister Injuries & Poisonings 0.921 0.818 – 1.04 0.174 302 2996 all phecode
912 Insect bite Injuries & Poisonings 0.972 0.886 – 1.07 0.547 492 4886 all phecode
913 Toxic effect of venom Injuries & Poisonings 0.925 0.827 – 1.04 0.179 337 3326 all phecode
916 Contusion Injuries & Poisonings 1 0.972 – 1.04 0.839 4296 38033 all phecode
930 Allergic reaction to food Injuries & Poisonings 0.987 0.916 – 1.06 0.729 763 7596 all phecode
931
Contact dermatitis and other eczema due to
Contact dermatitis and other eczema due to plants [except food]
 Dermatologic 1 0.928 – 1.08 0.937 714 7072 all phecode
938 Dermatitis due to solar radiation Dermatologic 1.01 0.985 – 1.04 0.359 5567 29098 all phecode
938.1 Acute dermatitis due to solar radiation Dermatologic 1.02 0.883 – 1.17 0.824 217 2164 all phecode
938.2 Chronic dermatitis due to solar radiation Dermatologic 1.01 0.983 – 1.04 0.419 5307 28656 all phecode
939
Atopic/contact dermatitis due to other or
Atopic/contact dermatitis due to other or unspecified
 Dermatologic 1 0.975 – 1.03 0.929 6704 32389 all phecode
939.1 Contact and allergic dermatitis of eyelid Dermatologic 0.899 0.728 – 1.11 0.322 91 870 all phecode
941 Adverse reaction to serum or vaccine Injuries & Poisonings 1.05 0.905 – 1.22 0.517 188 1880 all phecode
942 Infusion and transfusion reaction Injuries & Poisonings 1.05 0.927 – 1.19 0.434 269 2688 all phecode
946 Anaphylactic shock NOS Injuries & Poisonings 0.993 0.904 – 1.09 0.875 500 4940 all phecode
947 Urticaria Dermatologic 1.02 0.955 – 1.08 0.629 1177 11454 all phecode
949 Allergies, other Injuries & Poisonings 0.999 0.973 – 1.03 0.924 7251 32350 all phecode
952
Spinal cord injury without evidence of spinal
Spinal cord injury without evidence of spinal bone injury
 Injuries & Poisonings 1.1 1 – 1.21 0.0453 494 4940 all phecode
957 Injury to other and unspecified nerves Injuries & Poisonings 1.03 0.863 – 1.23 0.739 136 1352 all phecode
958
Certain early complications of trauma or
Certain early complications of trauma or procedure
 Injuries & Poisonings 0.991 0.934 – 1.05 0.771 1217 12158 all phecode
958.1 Postoperative shock Injuries & Poisonings 1.14 0.967 – 1.34 0.12 169 1688 all phecode
958.2 Traumatic and surgical subcutaneous emphysema Injuries & Poisonings 1.09 0.901 – 1.32 0.375 114 1140 all phecode
960 Poisoning by antibiotics Injuries & Poisonings 0.965 0.926 – 1.01 0.0939 2479 22087 all phecode
960.1
Adverse effects of antibacterials (not
Adverse effects of antibacterials (not penicillins)
 Injuries & Poisonings 0.988 0.884 – 1.1 0.825 342 3403 all phecode
960.2 Allergy/adverse effect of penicillin Injuries & Poisonings 0.973 0.924 – 1.02 0.287 1636 16005 all phecode
961 Poisoning by other anti-infectives Injuries & Poisonings 1.01 0.922 – 1.11 0.822 528 5234 all phecode
961.1 Poisoning/allergy of sulfonamides Injuries & Poisonings 0.957 0.898 – 1.02 0.17 1065 10347 all phecode
962 Poisoning by hormones and synthetic substitutes Injuries & Poisonings 0.99 0.92 – 1.07 0.796 803 7976 all phecode
962.1
Adrenal cortical steroids causing adverse
Adrenal cortical steroids causing adverse effects in therapeutic use
 Injuries & Poisonings 0.983 0.883 – 1.09 0.749 379 3782 all phecode
962.2
Insulins and antidiabetic agents causing
Insulins and antidiabetic agents causing adverse effects in therapeutic use
 Injuries & Poisonings 0.824 0.637 – 1.07 0.141 62 612 all phecode
962.3
Hormones and synthetic substitutes causing
Hormones and synthetic substitutes causing adverse effects in therapeutic use
 Injuries & Poisonings 1 0.911 – 1.1 0.991 478 4773 all phecode
963 Poisoning by primarily systemic agents Injuries & Poisonings 1.01 0.965 – 1.05 0.803 2533 24531 all phecode
963.1
Antineoplastic and immunosuppressive drugs
Antineoplastic and immunosuppressive drugs causing adverse effects
 Injuries & Poisonings 1.01 0.972 – 1.06 0.529 2469 24057 all phecode
964
Poisoning by agents primarily affecting blood
Poisoning by agents primarily affecting blood constituents
 Injuries & Poisonings 0.995 0.923 – 1.07 0.888 743 7337 all phecode
964.1 Anticoagulants causing adverse effects Injuries & Poisonings 0.985 0.913 – 1.06 0.707 712 7027 all phecode
965
Poisoning by analgesics, antipyretics, and
Poisoning by analgesics, antipyretics, and antirheumatics
 Injuries & Poisonings 1.04 0.97 – 1.12 0.268 864 8601 all phecode
965.1
Opiates and related narcotics causing adverse
Opiates and related narcotics causing adverse effects in therapeutic use
 Injuries & Poisonings 1.01 0.955 – 1.06 0.777 1469 14402 all phecode
965.3
Salicylates causing adverse effects in
Salicylates causing adverse effects in therapeutic use
 Injuries & Poisonings 1.09 0.908 – 1.31 0.35 119 1182 all phecode
966
Poisoning by anticonvulsants and
Poisoning by anticonvulsants and anti-Parkinsonism drugs
 Injuries & Poisonings 0.984 0.806 – 1.2 0.874 103 1006 all phecode
967
Adverse effects of sedatives or other central
Adverse effects of sedatives or other central nervous system depressants and anesthetics
 Injuries & Poisonings 0.966 0.911 – 1.02 0.239 1254 12464 all phecode
969 Poisoning by psychotropic agents Injuries & Poisonings 1.04 0.92 – 1.18 0.527 281 2797 all phecode
971
Poisoning by drugs primarily affecting the
Poisoning by drugs primarily affecting the autonomic nervous system
 Injuries & Poisonings 1.04 0.803 – 1.34 0.788 67 643 all phecode
972
Poisoning by agents primarily affecting the
Poisoning by agents primarily affecting the cardiovascular system
 Injuries & Poisonings 1.04 0.919 – 1.17 0.554 288 2858 all phecode
972.1
Cardiac rhythm regulators causing adverse
Cardiac rhythm regulators causing adverse effects in therapeutic use
 Injuries & Poisonings 1.19 0.939 – 1.51 0.151 80 776 all phecode
972.6 Antihypertensive agents causing adverse effects Injuries & Poisonings 0.889 0.73 – 1.08 0.241 104 1034 all phecode
974
Poisoning by water, mineral, and uric acid
Poisoning by water, mineral, and uric acid metabolism drugs
 Injuries & Poisonings 1.12 0.926 – 1.36 0.242 113 1130 all phecode
975
Poisoning by agents primarily acting on the
Poisoning by agents primarily acting on the smooth and skeletal muscles and respiratory system
 Injuries & Poisonings 0.899 0.718 – 1.13 0.356 81 810 all phecode
976
Poisoning by agents primarily affecting skin &
Poisoning by agents primarily affecting skin & mucous membrane, ophthalmological, otorhinolaryngological, & dental drugs
 Injuries & Poisonings 1.28 0.993 – 1.66 0.0568 71 703 all phecode
977 Personal history of allergy to medicinal agents Injuries & Poisonings 0.967 0.921 – 1.02 0.183 1763 16599 all phecode
979 Adverse drug events and drug allergies Injuries & Poisonings 1.01 0.972 – 1.04 0.683 3448 30885 all phecode
980
Encounter for long-term (current) use of
Encounter for long-term (current) use of antibiotics
 Infectious Diseases 0.98 0.927 – 1.04 0.473 1391 13877 all phecode
985 Toxic effect of other metals Injuries & Poisonings 1.48 1.11 – 1.97 0.0069 57 564 all phecode
989
Toxic effect of other substances, chiefly
Toxic effect of other substances, chiefly nonmedicinal as to source
 Injuries & Poisonings 0.97 0.811 – 1.16 0.738 129 1275 all phecode
990 Effects radiation NOS Injuries & Poisonings 1.01 0.977 – 1.04 0.544 3927 31223 all phecode
994 Sepsis and SIRS Injuries & Poisonings 1.01 0.962 – 1.05 0.809 2192 21710 all phecode
994.1 Systemic inflammatory response syndrome (SIRS) Injuries & Poisonings 0.928 0.822 – 1.05 0.223 291 2910 all phecode
994.2 Sepsis Injuries & Poisonings 1.01 0.965 – 1.06 0.675 2086 20666 all phecode
994.21 Septic shock Injuries & Poisonings 0.98 0.904 – 1.06 0.625 627 6260 all phecode
008 Intestinal infection Infectious Diseases 1 0.944 – 1.07 0.883 1214 5969 exclusion phecode
008.5 Bacterial enteritis Infectious Diseases 1.07 0.97 – 1.18 0.179 510 2623 exclusion phecode
008.52 Intestinal infection due to C. difficile Infectious Diseases 1.08 0.97 – 1.21 0.158 397 2047 exclusion phecode
008.6 Viral Enteritis Infectious Diseases 0.971 0.864 – 1.09 0.617 359 1633 exclusion phecode
010 Tuberculosis Infectious Diseases 1.09 0.86 – 1.38 0.474 80 466 exclusion phecode
031 Diseases due to other mycobacteria Infectious Diseases 0.829 0.59 – 1.16 0.28 40 184 exclusion phecode
038 Septicemia Infectious Diseases 1.08 1.01 – 1.15 0.0337 1053 4659 exclusion phecode
038.1 Gram negative septicemia Infectious Diseases 1.04 0.91 – 1.18 0.584 276 1157 exclusion phecode
038.2 Gram positive septicemia Infectious Diseases 0.946 0.751 – 1.19 0.635 106 482 exclusion phecode
038.3 Bacteremia Infectious Diseases 1.06 0.967 – 1.16 0.21 573 2429 exclusion phecode
041 Bacterial infection NOS Infectious Diseases 1.05 0.995 – 1.1 0.0782 2016 7043 exclusion phecode
041.1 Staphylococcus infections Infectious Diseases 1.06 0.972 – 1.16 0.18 588 3190 exclusion phecode
041.11 Methicillin sensitive Staphylococcus aureus Infectious Diseases 1.06 0.944 – 1.19 0.331 362 1830 exclusion phecode
041.12 Methicillin resistant Staphylococcus aureus Infectious Diseases 1.08 0.943 – 1.24 0.265 256 1459 exclusion phecode
041.2 Streptococcus infection Infectious Diseases 1.02 0.942 – 1.12 0.569 660 3108 exclusion phecode
041.21 Rheumatic fever / chorea Infectious Diseases 1.1 0.863 – 1.39 0.452 77 495 exclusion phecode
041.4 E. coli Infectious Diseases 1.06 0.957 – 1.17 0.275 481 2254 exclusion phecode
041.8 H. pylori Infectious Diseases 0.845 0.663 – 1.08 0.176 84 501 exclusion phecode
041.9 Infection with drug-resistant microorganisms Infectious Diseases 1.08 0.912 – 1.28 0.371 167 713 exclusion phecode
053 Herpes zoster Infectious Diseases 0.96 0.88 – 1.05 0.356 635 2754 exclusion phecode
053.1 Herpes zoster with nervous system complications Infectious Diseases 0.895 0.705 – 1.14 0.361 89 383 exclusion phecode
054 Herpes simplex Infectious Diseases 0.983 0.897 – 1.08 0.721 542 2601 exclusion phecode
070 Viral hepatitis Infectious Diseases 0.967 0.847 – 1.1 0.613 269 1416 exclusion phecode
070.1 Viral hepatitis A Infectious Diseases 0.692 0.444 – 1.08 0.105 22 157 exclusion phecode
070.2 Viral hepatitis B Infectious Diseases 0.967 0.738 – 1.27 0.806 69 338 exclusion phecode
070.3 Viral hepatitis C Infectious Diseases 0.968 0.826 – 1.14 0.69 179 886 exclusion phecode
070.4 Chronic hepatitis Infectious Diseases 1.14 0.898 – 1.45 0.277 87 339 exclusion phecode
070.9 Hepatitis NOS Infectious Diseases 0.983 0.877 – 1.1 0.771 355 1924 exclusion phecode
071 Human immunodeficiency virus [HIV] disease Infectious Diseases 1.21 0.895 – 1.63 0.215 58 266 exclusion phecode
071.1 HIV infection, symptomatic Infectious Diseases 1.41 0.992 – 2.01 0.0551 48 209 exclusion phecode
078 Viral warts & HPV Infectious Diseases 0.99 0.931 – 1.05 0.756 1270 4660 exclusion phecode
079 Viral infection Infectious Diseases 1.02 0.973 – 1.07 0.4 2623 5564 exclusion phecode
079.1 Varicella infection Infectious Diseases 0.997 0.94 – 1.06 0.924 1417 5081 exclusion phecode
079.2 Infectious mononucleosis Infectious Diseases 1.12 0.877 – 1.43 0.367 83 420 exclusion phecode
079.9 Viremia, NOS Infectious Diseases 1.1 0.983 – 1.24 0.0943 402 1449 exclusion phecode
080 Postoperative infection Infectious Diseases 1.02 0.941 – 1.1 0.673 735 4968 exclusion phecode
081
Infection/inflammation of internal prosthetic
Infection/inflammation of internal prosthetic device; implant; and graft
 Infectious Diseases 1.07 0.969 – 1.17 0.189 508 3016 exclusion phecode
090
Sexually transmitted infections (not HIV or
Sexually transmitted infections (not HIV or hepatitis)
 Infectious Diseases 1.17 1.04 – 1.3 0.00724 364 2162 exclusion phecode
110 Dermatophytosis / Dermatomycosis Infectious Diseases 1 0.947 – 1.06 0.979 1708 5487 exclusion phecode
110.1 Dermatophytosis Infectious Diseases 0.994 0.939 – 1.05 0.846 1602 5067 exclusion phecode
110.11 Dermatophytosis of nail Infectious Diseases 1.02 0.956 – 1.1 0.5 1103 3455 exclusion phecode
110.12 Althete's foot Infectious Diseases 1.06 0.954 – 1.17 0.286 468 1839 exclusion phecode
110.13 Dermatophytosis of the body Infectious Diseases 0.986 0.874 – 1.11 0.812 340 1572 exclusion phecode
110.2 Dermatomycoses Infectious Diseases 0.998 0.839 – 1.19 0.98 153 785 exclusion phecode
112 Candidiasis Infectious Diseases 1.07 1.01 – 1.14 0.0218 1296 5197 exclusion phecode
112.3 Candidiasis of skin and nails Infectious Diseases 0.947 0.833 – 1.08 0.403 269 1195 exclusion phecode
117 Mycoses Infectious Diseases 1.06 0.914 – 1.23 0.432 212 1115 exclusion phecode
117.1 Histoplasmosis Infectious Diseases 0.972 0.628 – 1.5 0.898 20 160 exclusion phecode
117.4 Aspergillosis Infectious Diseases 1.15 0.852 – 1.56 0.358 55 271 exclusion phecode
130 Spirochetal infection Infectious Diseases 0.953 0.726 – 1.25 0.727 60 301 exclusion phecode
130.1 Lyme disease Infectious Diseases 1.06 0.756 – 1.5 0.722 38 203 exclusion phecode
131 Protozoan infection Infectious Diseases 0.654 0.386 – 1.11 0.114 17 109 exclusion phecode
132 Infestation (lice, mites) Infectious Diseases 0.778 0.611 – 0.99 0.0414 73 401 exclusion phecode
134 Helminthiases Infectious Diseases 0.945 0.647 – 1.38 0.769 31 156 exclusion phecode
134.1 Intestinal helminthiases Infectious Diseases 0.955 0.561 – 1.63 0.866 18 114 exclusion phecode
136 Other infectious and parasitic diseases Infectious Diseases 1.02 0.952 – 1.08 0.634 1123 6410 exclusion phecode
145 Cancer of mouth Neoplasms 0.892 0.768 – 1.04 0.132 176 2974 exclusion phecode
145.1 Cancer of lip Neoplasms 0.766 0.402 – 1.46 0.417 9 130 exclusion phecode
145.2 Cancer of tongue Neoplasms 0.78 0.608 – 1 0.0501 65 1291 exclusion phecode
145.3 Cancer of major salivary glands Neoplasms 0.944 0.718 – 1.24 0.676 54 741 exclusion phecode
145.4 Cancer of the gums Neoplasms 0.575 0.322 – 1.03 0.0615 12 321 exclusion phecode
145.5 Cancer of the mouth floor Neoplasms 1.08 0.704 – 1.64 0.735 18 383 exclusion phecode
149 Cancer of larynx, pharynx, nasal cavities Neoplasms 0.876 0.746 – 1.03 0.103 152 2619 exclusion phecode
149.1 Cancer of oropharynx Neoplasms 0.907 0.692 – 1.19 0.478 53 746 exclusion phecode
149.2 Cancer of nasopharynx Neoplasms 1.15 0.666 – 1.98 0.616 13 204 exclusion phecode
149.3 Cancer of hypopharynx Neoplasms 1.31 0.696 – 2.46 0.403 8 177 exclusion phecode
149.4 Cancer of larynx Neoplasms 0.713 0.524 – 0.97 0.0313 42 796 exclusion phecode
149.5
Hx of malignant neoplasm of oral cavity and
Hx of malignant neoplasm of oral cavity and pharynx
 Neoplasms 0.829 0.67 – 1.02 0.0823 85 1120 exclusion phecode
149.9 Cancer of of nasal cavities Neoplasms 1.2 0.803 – 1.79 0.375 23 467 exclusion phecode
150 Cancer of esophagus Neoplasms 0.963 0.754 – 1.23 0.761 69 805 exclusion phecode
151 Cancer of stomach Neoplasms 1.05 0.851 – 1.31 0.631 93 960 exclusion phecode
153 Colorectal cancer Neoplasms 1.02 0.909 – 1.14 0.735 344 2154 exclusion phecode
153.2 Colon cancer Neoplasms 1.04 0.91 – 1.18 0.596 278 1712 exclusion phecode
153.3
Malignant neoplasm of rectum, rectosigmoid
Malignant neoplasm of rectum, rectosigmoid junction, and anus
 Neoplasms 1.03 0.882 – 1.2 0.704 186 1173 exclusion phecode
155 Cancer of liver and intrahepatic bile duct Neoplasms 1.21 0.995 – 1.47 0.0564 119 908 exclusion phecode
155.1 Malignant neoplasm of liver, primary Neoplasms 1.14 0.907 – 1.44 0.258 89 643 exclusion phecode
157 Pancreatic cancer Neoplasms 1 0.821 – 1.23 0.974 105 933 exclusion phecode
158
Neoplasm of unspecified nature of digestive
Neoplasm of unspecified nature of digestive system
 Neoplasms 0.957 0.871 – 1.05 0.365 505 3056 exclusion phecode
159
Malignant neoplasm of other and ill-defined
Malignant neoplasm of other and ill-defined sites within the digestive organs and peritoneum
 Neoplasms 1.03 0.932 – 1.14 0.554 440 3215 exclusion phecode
159.2
Malignant neoplasm of small intestine
Malignant neoplasm of small intestine, including duodenum
 Neoplasms 1.01 0.752 – 1.36 0.932 45 409 exclusion phecode
159.3
Malignant neoplasm of gallbladder and
Malignant neoplasm of gallbladder and extrahepatic bile ducts
 Neoplasms 1.03 0.675 – 1.57 0.894 22 330 exclusion phecode
159.4
Malignant neoplasm of retroperitoneum and
Malignant neoplasm of retroperitoneum and peritoneum
 Neoplasms 0.89 0.694 – 1.14 0.356 61 497 exclusion phecode
164 Cancer of intrathoracic organs Neoplasms 0.975 0.702 – 1.35 0.879 32 266 exclusion phecode
165 Cancer within the respiratory system Neoplasms 0.934 0.822 – 1.06 0.292 267 2696 exclusion phecode
165.1 Cancer of bronchus; lung Neoplasms 0.925 0.808 – 1.06 0.253 238 2162 exclusion phecode
170 Cancer of bone and connective tissue Neoplasms 0.923 0.808 – 1.05 0.236 224 3471 exclusion phecode
170.1 Bone cancer Neoplasms 0.894 0.731 – 1.09 0.273 99 1447 exclusion phecode
170.2 Cancer of connective tissue Neoplasms 0.915 0.782 – 1.07 0.268 157 2411 exclusion phecode
172 Skin cancer Neoplasms 0.959 0.908 – 1.01 0.133 1821 6592 exclusion phecode
172.1 Melanomas of skin, dx or hx Neoplasms 0.95 0.892 – 1.01 0.115 1220 5962 exclusion phecode
172.11 Melanomas of skin Neoplasms 0.892 0.807 – 0.986 0.0252 415 4893 exclusion phecode
172.2 Other non-epithelial cancer of skin Neoplasms 0.952 0.899 – 1.01 0.0899 1641 6121 exclusion phecode
172.21 Basal cell carcinoma Neoplasms 0.972 0.906 – 1.04 0.414 1011 4915 exclusion phecode
172.22 Squamous cell carcinoma Neoplasms 0.998 0.915 – 1.09 0.973 603 3747 exclusion phecode
172.3 Carcinoma in situ of skin Neoplasms 0.999 0.902 – 1.11 0.991 426 2789 exclusion phecode
173 Neoplasm of uncertain behavior of skin Neoplasms 0.976 0.897 – 1.06 0.561 645 4064 exclusion phecode
174 Breast cancer Neoplasms 0.965 0.884 – 1.05 0.429 644 2590 exclusion phecode
174.1 Breast cancer [female] Neoplasms 0.971 0.887 – 1.06 0.522 605 2403 exclusion phecode
174.11 Malignant neoplasm of female breast Neoplasms 0.978 0.893 – 1.07 0.638 592 2376 exclusion phecode
174.3 Neoplasm of uncertain behavior of breast Neoplasms 1.16 0.893 – 1.5 0.266 54 391 exclusion phecode
175 Acquired absence of breast Neoplasms 1.05 0.898 – 1.23 0.54 182 1160 exclusion phecode
180 Cervical cancer and dysplasia Neoplasms 0.988 0.88 – 1.11 0.838 357 1919 exclusion phecode
180.1 Cervical cancer Neoplasms 0.982 0.782 – 1.23 0.874 74 719 exclusion phecode
180.3
Cervical intraepithelial neoplasia [CIN]
Cervical intraepithelial neoplasia [CIN] [Cervical dysplasia]
 Neoplasms 0.985 0.867 – 1.12 0.812 307 1441 exclusion phecode
182 Malignant neoplasm of uterus Neoplasms 0.9 0.754 – 1.07 0.241 133 1214 exclusion phecode
184 Cancer of other female genital organs Neoplasms 0.979 0.86 – 1.12 0.752 243 2012 exclusion phecode
184.1
Malignant neoplasm of ovary and other uterine
Malignant neoplasm of ovary and other uterine adnexa
 Neoplasms 0.921 0.759 – 1.12 0.404 102 982 exclusion phecode
184.11 Malignant neoplasm of ovary Neoplasms 0.905 0.723 – 1.13 0.384 74 734 exclusion phecode
184.2
Cancer of other female genital organs
Cancer of other female genital organs (excluding uterus and ovary)
 Neoplasms 0.986 0.834 – 1.17 0.872 145 1084 exclusion phecode
185 Cancer of prostate Neoplasms 0.93 0.839 – 1.03 0.161 542 2021 exclusion phecode
187 Cancer of other male genital organs Neoplasms 1.02 0.81 – 1.3 0.84 75 724 exclusion phecode
187.1
Malignant neoplasm of unspecified male genital
Malignant neoplasm of unspecified male genital organ
 Neoplasms 0.929 0.598 – 1.44 0.741 21 249 exclusion phecode
187.2 Malignant neoplasm of testis Neoplasms 1.16 0.838 – 1.61 0.365 36 355 exclusion phecode
187.8
Neoplasm of uncertain behavior of male genital
Neoplasm of uncertain behavior of male genital organs
 Neoplasms 0.874 0.568 – 1.34 0.541 24 138 exclusion phecode
189
Cancer of urinary organs (incl. kidney and
Cancer of urinary organs (incl. kidney and bladder)
 Neoplasms 1.04 0.95 – 1.13 0.41 564 4858 exclusion phecode
189.1 Cancer of kidney and renal pelvis Neoplasms 0.952 0.843 – 1.08 0.428 272 3046 exclusion phecode
189.11 Malignant neoplasm of kidney, except pelvis Neoplasms 0.956 0.836 – 1.09 0.511 229 2649 exclusion phecode
189.12 Malignant neoplasm of renal pelvis Neoplasms 0.846 0.631 – 1.13 0.265 45 541 exclusion phecode
189.2 Cancer of bladder Neoplasms 1.1 0.986 – 1.23 0.087 354 3303 exclusion phecode
189.21 Malignant neoplasm of bladder Neoplasms 1.09 0.97 – 1.23 0.148 313 3088 exclusion phecode
189.4 Malignant neoplasm of other urinary organs Neoplasms 1.17 0.981 – 1.4 0.0806 132 1446 exclusion phecode
190 Cancer of eye Neoplasms 0.742 0.493 – 1.12 0.153 25 269 exclusion phecode
191
Manlignant and unknown neoplasms of brain and
Manlignant and unknown neoplasms of brain and nervous system
 Neoplasms 0.962 0.82 – 1.13 0.631 156 1935 exclusion phecode
191.1 Cancer of brain and nervous system Neoplasms 0.963 0.789 – 1.18 0.712 92 1242 exclusion phecode
191.11 Cancer of brain Neoplasms 0.999 0.795 – 1.25 0.993 73 1025 exclusion phecode
193 Thyroid cancer Neoplasms 1.03 0.877 – 1.21 0.709 162 1804 exclusion phecode
194 Cancer of other endocrine glands Neoplasms 1.11 0.92 – 1.35 0.267 121 1191 exclusion phecode
195 Cancer, suspected or other Neoplasms 1.01 0.963 – 1.06 0.694 3427 5196 exclusion phecode
195.1 Malignant neoplasm, other Neoplasms 1.01 0.961 – 1.06 0.766 3391 5188 exclusion phecode
195.3 Malignant neoplasm of head, face, and neck Neoplasms 0.915 0.784 – 1.07 0.259 168 1912 exclusion phecode
196 Radiotherapy Neoplasms 0.956 0.873 – 1.05 0.335 550 3273 exclusion phecode
197 Chemotherapy Neoplasms 1.03 0.961 – 1.1 0.406 1033 4586 exclusion phecode
198 Secondary malignant neoplasm Neoplasms 1.01 0.935 – 1.09 0.84 866 4413 exclusion phecode
198.1 Secondary malignancy of lymph nodes Neoplasms 1.02 0.925 – 1.12 0.72 482 3986 exclusion phecode
198.2 Secondary malignancy of respiratory organs Neoplasms 0.921 0.793 – 1.07 0.283 187 1946 exclusion phecode
198.3
Secondary malignant neoplasm of digestive
Secondary malignant neoplasm of digestive systems
 Neoplasms 0.925 0.785 – 1.09 0.353 151 1569 exclusion phecode
198.4 Secondary malignant neoplasm of liver Neoplasms 1.01 0.845 – 1.2 0.952 134 1459 exclusion phecode
198.5 Secondary malignancy of brain/spine Neoplasms 0.956 0.773 – 1.18 0.68 89 1150 exclusion phecode
198.6 Secondary malignancy of bone Neoplasms 1.04 0.886 – 1.22 0.627 161 1559 exclusion phecode
198.7 Secondary malignant neoplasm of skin Neoplasms 0.773 0.593 – 1.01 0.0557 52 691 exclusion phecode
199 Neoplasm of uncertain behavior Neoplasms 1.01 0.953 – 1.08 0.665 1372 5086 exclusion phecode
199.4 Neurofibromatosis Neoplasms 0.944 0.538 – 1.66 0.842 11 156 exclusion phecode
200 Myeloproliferative disease Neoplasms 1.01 0.914 – 1.12 0.8 441 2412 exclusion phecode
200.1 Polycythemia vera Neoplasms 1.02 0.834 – 1.24 0.855 117 527 exclusion phecode
201 Hodgkin's disease Neoplasms 0.931 0.711 – 1.22 0.604 57 345 exclusion phecode
202 Cancer of other lymphoid, histiocytic tissue Neoplasms 0.957 0.859 – 1.07 0.431 378 3215 exclusion phecode
202.2 Non-Hodgkins lymphoma Neoplasms 0.943 0.837 – 1.06 0.327 314 2764 exclusion phecode
202.21 Nodular lymphoma Neoplasms 0.863 0.735 – 1.01 0.0739 158 1411 exclusion phecode
202.22 Reticulosarcoma Neoplasms 1.11 0.801 – 1.53 0.538 43 375 exclusion phecode
202.24 Large cell lymphoma Neoplasms 1.26 0.892 – 1.78 0.19 36 342 exclusion phecode
204 Leukemia Neoplasms 1.06 0.92 – 1.21 0.435 240 1578 exclusion phecode
204.1 Lymphoid leukemia Neoplasms 0.935 0.721 – 1.21 0.609 63 517 exclusion phecode
204.11 Lymphoid leukemia, acute Neoplasms 0.838 0.538 – 1.31 0.437 27 158 exclusion phecode
204.12 Lymphoid leukemia, chronic Neoplasms 1.01 0.752 – 1.35 0.952 46 386 exclusion phecode
204.2 Myeloid leukemia Neoplasms 1.12 0.91 – 1.39 0.279 121 663 exclusion phecode
204.21 Myeloid leukemia, acute Neoplasms 1.11 0.84 – 1.46 0.465 72 389 exclusion phecode
204.22 Myeloid leukemia, chronic Neoplasms 1.19 0.736 – 1.92 0.479 23 135 exclusion phecode
204.4 Multiple myeloma Neoplasms 0.999 0.788 – 1.27 0.993 77 503 exclusion phecode
208 Benign neoplasm of colon Neoplasms 0.976 0.934 – 1.02 0.266 3725 5595 exclusion phecode
209 Neuroendocrine tumors Neoplasms 1.03 0.796 – 1.33 0.831 63 546 exclusion phecode
210 Benign neoplasm of lip, oral cavity, and pharynx Neoplasms 0.934 0.829 – 1.05 0.262 295 3630 exclusion phecode
211
Benign neoplasm of other parts of digestive
Benign neoplasm of other parts of digestive system
 Neoplasms 0.987 0.942 – 1.03 0.579 2509 6533 exclusion phecode
212
Benign neoplasm of respiratory and
Benign neoplasm of respiratory and intrathoracic organs
 Neoplasms 1.03 0.93 – 1.15 0.548 391 3505 exclusion phecode
213 Benign neoplasm of bone and articular cartilage Neoplasms 0.943 0.838 – 1.06 0.334 332 2266 exclusion phecode
214 Lipoma Neoplasms 1.05 0.952 – 1.16 0.314 459 2915 exclusion phecode
214.1 Lipoma of skin and subcutaneous tissue Neoplasms 1.02 0.901 – 1.16 0.711 280 1774 exclusion phecode
215
Other benign neoplasm of connective and other
Other benign neoplasm of connective and other soft tissue
 Neoplasms 0.969 0.908 – 1.03 0.344 1054 7625 exclusion phecode
216 Benign neoplasm of skin Neoplasms 0.964 0.925 – 1.01 0.0909 3606 5974 exclusion phecode
216.1 Screening for malignant neoplasms of the skin Neoplasms 0.687 0.521 – 0.905 0.00762 68 309 exclusion phecode
217 Vascular hamartomas and non-neoplastic nevi Neoplasms 0.92 0.844 – 1 0.0576 645 3218 exclusion phecode
217.1 Nevus, non-neoplastic Neoplasms 0.919 0.842 – 1 0.0581 623 3080 exclusion phecode
218 Benign neoplasm of uterus Neoplasms 0.888 0.829 – 0.951 0.000717 1199 2769 exclusion phecode
218.1 Uterine leiomyoma Neoplasms 0.808 0.734 – 0.89 1.6e-05 494 2563 exclusion phecode
218.2 Other benign neoplasm of uterus Neoplasms 0.876 0.813 – 0.944 0.00051 967 2696 exclusion phecode
220 Benign neoplasm of ovary Neoplasms 0.912 0.787 – 1.06 0.22 206 1249 exclusion phecode
221 Benign neoplasm of other female genital organs Neoplasms 0.91 0.822 – 1.01 0.0708 445 2224 exclusion phecode
222 Benign neoplasm of male genital organs Neoplasms 0.956 0.847 – 1.08 0.466 297 2486 exclusion phecode
223
Benign neoplasm of kidney and other urinary
Benign neoplasm of kidney and other urinary organs
 Neoplasms 1.01 0.903 – 1.14 0.813 370 1867 exclusion phecode
224 Benign neoplasm of eye Neoplasms 0.946 0.833 – 1.07 0.387 283 1709 exclusion phecode
224.1 Benign neoplasm of eye, uveal Neoplasms 0.973 0.852 – 1.11 0.687 257 1504 exclusion phecode
225
Benign neoplasm of brain and other parts of
Benign neoplasm of brain and other parts of nervous system
 Neoplasms 0.931 0.808 – 1.07 0.322 204 2269 exclusion phecode
225.1
Benign neoplasm of brain, cranial nerves
Benign neoplasm of brain, cranial nerves, meninges
 Neoplasms 0.992 0.837 – 1.17 0.922 145 1751 exclusion phecode
225.2 Benign neoplasm of spinal cord, meninges Neoplasms 0.8 0.614 – 1.04 0.0974 58 537 exclusion phecode
226 Benign neoplasm of thyroid glands Neoplasms 1.01 0.9 – 1.13 0.86 312 2658 exclusion phecode
227
Benign neoplasm of other endocrine glands and
Benign neoplasm of other endocrine glands and related structures
 Neoplasms 1.05 0.935 – 1.18 0.418 327 3275 exclusion phecode
227.1 Benign neoplasm of adrenal gland Neoplasms 1.2 0.996 – 1.44 0.0558 137 1018 exclusion phecode
227.2 Benign neoplasm of parathyroid gland Neoplasms 1.1 0.917 – 1.32 0.309 133 1391 exclusion phecode
227.3
Benign neoplasm of pituitary gland and
Benign neoplasm of pituitary gland and craniopharyngeal duct (pouch)
 Neoplasms 0.921 0.719 – 1.18 0.51 63 870 exclusion phecode
228 Hemangioma and lymphangioma, any site Neoplasms 0.941 0.869 – 1.02 0.131 709 4626 exclusion phecode
228.1 Hemangioma of skin and subcutaneous tissue Neoplasms 0.909 0.826 – 1 0.049 494 3047 exclusion phecode
229 Benign neoplasm of unspecified sites Neoplasms 0.987 0.929 – 1.05 0.663 1244 7465 exclusion phecode
229.1 Benign neoplasm of lymph nodes Neoplasms 1.01 0.933 – 1.09 0.84 724 6719 exclusion phecode
240 Simple and unspecified goiter Endocrine/metabolic 1.06 0.945 – 1.19 0.322 337 2007 exclusion phecode
241 Nontoxic nodular goiter Endocrine/metabolic 1.02 0.949 – 1.1 0.554 828 4383 exclusion phecode
241.1 Nontoxic uninodular goiter Endocrine/metabolic 1.02 0.936 – 1.1 0.707 663 3845 exclusion phecode
241.2 Nontoxic multinodular goiter Endocrine/metabolic 1.06 0.952 – 1.18 0.286 383 2424 exclusion phecode
242 Thyrotoxicosis with or without goiter Endocrine/metabolic 1.02 0.921 – 1.12 0.747 466 2750 exclusion phecode
242.1 Graves' disease Endocrine/metabolic 0.956 0.8 – 1.14 0.618 137 1024 exclusion phecode
242.2 Toxic multinodular goiter Endocrine/metabolic 1.27 0.887 – 1.82 0.191 36 262 exclusion phecode
242.3 Exophthalmos Endocrine/metabolic 1.14 0.894 – 1.46 0.285 79 577 exclusion phecode
242.31 Thyrotoxic exophthalmos Endocrine/metabolic 0.701 0.48 – 1.02 0.0656 33 262 exclusion phecode
244 Hypothyroidism Endocrine/metabolic 1.02 0.968 – 1.07 0.478 2072 6377 exclusion phecode
244.1 Secondary hypothyroidism Endocrine/metabolic 1.04 0.936 – 1.15 0.482 402 3305 exclusion phecode
244.2 Acquired hypothyroidism Endocrine/metabolic 1.15 1.04 – 1.27 0.00782 441 2531 exclusion phecode
244.4 Hypothyroidism NOS Endocrine/metabolic 1.02 0.966 – 1.07 0.504 1995 6295 exclusion phecode
245 Thyroiditis Endocrine/metabolic 1.07 0.939 – 1.22 0.315 260 1745 exclusion phecode
245.2 Chronic thyroiditis Endocrine/metabolic 1.05 0.911 – 1.21 0.492 217 1448 exclusion phecode
245.21 Chronic lymphocytic thyroiditis Endocrine/metabolic 1.04 0.901 – 1.2 0.588 216 1447 exclusion phecode
246 Other disorders of thyroid Endocrine/metabolic 0.977 0.922 – 1.04 0.447 1482 5893 exclusion phecode
246.2 Thyroid cyst Endocrine/metabolic 0.743 0.506 – 1.09 0.129 31 197 exclusion phecode
246.7 Abnormal results of function study of thyroid Endocrine/metabolic 1.05 0.943 – 1.18 0.35 354 1926 exclusion phecode
249 Secondary diabetes mellitus Endocrine/metabolic 1.02 0.912 – 1.13 0.784 691 1087 exclusion phecode
250 Diabetes mellitus Endocrine/metabolic 1.04 0.995 – 1.09 0.0825 5139 4378 exclusion phecode
250.1 Type 1 diabetes Endocrine/metabolic 1.04 0.946 – 1.13 0.45 1559 1539 exclusion phecode
250.11 Type 1 diabetes with ketoacidosis Endocrine/metabolic 0.955 0.748 – 1.22 0.709 175 146 exclusion phecode
250.12 Type 1 diabetes with renal manifestations Endocrine/metabolic 0.963 0.814 – 1.14 0.657 391 391 exclusion phecode
250.13 Type 1 diabetes with ophthalmic manifestations Endocrine/metabolic 1.06 0.902 – 1.24 0.502 566 411 exclusion phecode
250.14 Type 1 diabetes with neurological manifestations Endocrine/metabolic 1.06 0.899 – 1.25 0.491 462 364 exclusion phecode
250.15
Diabetes type 1 with peripheral circulatory
Diabetes type 1 with peripheral circulatory disorders
 Endocrine/metabolic 0.93 0.693 – 1.25 0.631 123 117 exclusion phecode
250.2 Type 2 diabetes Endocrine/metabolic 1.07 1.01 – 1.13 0.0124 3804 4047 exclusion phecode
250.21 Type 2 diabetes with ketoacidosis Endocrine/metabolic 1.04 0.825 – 1.3 0.754 181 181 exclusion phecode
250.22 Type 2 diabetes with renal manifestations Endocrine/metabolic 1.12 1.03 – 1.22 0.00792 1254 1797 exclusion phecode
250.23 Type 2 diabetes with ophthalmic manifestations Endocrine/metabolic 1 0.911 – 1.1 0.959 1123 1301 exclusion phecode
250.24 Type 2 diabetes with neurological manifestations Endocrine/metabolic 1.08 0.999 – 1.16 0.0516 1590 2173 exclusion phecode
250.25
Diabetes type 2 with peripheral circulatory
Diabetes type 2 with peripheral circulatory disorders
 Endocrine/metabolic 1.08 0.964 – 1.22 0.177 593 876 exclusion phecode
250.3 Insulin pump user Endocrine/metabolic 1.1 1.03 – 1.19 0.00563 2021 2716 exclusion phecode
250.4 Abnormal glucose Endocrine/metabolic 1.02 0.973 – 1.08 0.37 3800 4234 exclusion phecode
250.41 Impaired fasting glucose Endocrine/metabolic 0.986 0.906 – 1.07 0.738 833 2258 exclusion phecode
250.42 Other abnormal glucose Endocrine/metabolic 1.03 0.977 – 1.08 0.276 3471 4153 exclusion phecode
250.5 Glycosuria or Acetonuria Endocrine/metabolic 1.24 0.852 – 1.8 0.263 63 166 exclusion phecode
250.6 Polyneuropathy in diabetes Endocrine/metabolic 1.07 0.983 – 1.16 0.121 1388 1776 exclusion phecode
250.7 Diabetic retinopathy Endocrine/metabolic 1.01 0.935 – 1.09 0.845 1153 2114 exclusion phecode
251 Other disorders of pancreatic internal secretion Endocrine/metabolic 1.04 0.941 – 1.14 0.454 510 1961 exclusion phecode
251.1 Hypoglycemia Endocrine/metabolic 1.1 0.98 – 1.23 0.108 653 1107 exclusion phecode
252 Disorders of parathyroid gland Endocrine/metabolic 1.07 0.986 – 1.15 0.107 752 3989 exclusion phecode
252.1 Hyperparathyroidism Endocrine/metabolic 1.09 1 – 1.18 0.0434 702 3700 exclusion phecode
252.2 Hypoparathyroidism Endocrine/metabolic 1.11 0.932 – 1.33 0.234 136 871 exclusion phecode
253
Disorders of the pituitary gland and its
Disorders of the pituitary gland and its hypothalamic control
 Endocrine/metabolic 1 0.877 – 1.14 0.981 242 1739 exclusion phecode
253.1 Pituitary hyperfunction Endocrine/metabolic 1.05 0.82 – 1.35 0.694 69 537 exclusion phecode
253.11 Acromegaly and gigantism Endocrine/metabolic 1.35 0.783 – 2.34 0.278 12 144 exclusion phecode
253.2 Pituitary hypofunction Endocrine/metabolic 1.04 0.779 – 1.4 0.772 45 419 exclusion phecode
253.3 Diabetes insipidus Endocrine/metabolic 0.953 0.661 – 1.38 0.799 33 191 exclusion phecode
253.4 Anterior pituitary disorders Endocrine/metabolic 0.793 0.572 – 1.1 0.163 48 309 exclusion phecode
253.7 Other disorders of neurohypophysis Endocrine/metabolic 1.06 0.788 – 1.43 0.699 40 201 exclusion phecode
255 Disorders of adrenal glands Endocrine/metabolic 1.04 0.941 – 1.15 0.455 459 2954 exclusion phecode
255.1 Adrenal hyperfunction Endocrine/metabolic 1.02 0.848 – 1.22 0.85 118 715 exclusion phecode
255.11 Cushing's syndrome Endocrine/metabolic 1.06 0.801 – 1.41 0.677 48 361 exclusion phecode
255.12 Hyperaldosteronism Endocrine/metabolic 1.01 0.73 – 1.4 0.944 42 270 exclusion phecode
255.2 Adrenal hypofunction Endocrine/metabolic 1.18 1.01 – 1.38 0.0405 194 1232 exclusion phecode
255.21 Glucocorticoid deficiency Endocrine/metabolic 1.17 0.998 – 1.37 0.0527 185 1168 exclusion phecode
256 Ovarian dysfunction Endocrine/metabolic 0.919 0.824 – 1.03 0.132 387 1873 exclusion phecode
256.4 Polycystic ovaries Endocrine/metabolic 0.955 0.837 – 1.09 0.494 264 1315 exclusion phecode
257 Testicular dysfunction Endocrine/metabolic 0.95 0.856 – 1.05 0.328 460 1943 exclusion phecode
257.1 Testicular hypofunction Endocrine/metabolic 0.957 0.862 – 1.06 0.414 447 1876 exclusion phecode
258 Iatrogenic endocrine disorders Endocrine/metabolic 1.11 0.762 – 1.62 0.582 34 227 exclusion phecode
258.1 Postablative ovarian failure Endocrine/metabolic 1.09 0.766 – 1.55 0.627 38 180 exclusion phecode
259 Other endocrine disorders Endocrine/metabolic 1.08 0.964 – 1.2 0.189 388 2138 exclusion phecode
260 Protein-calorie malnutrition Endocrine/metabolic 1.07 0.991 – 1.15 0.0877 888 4113 exclusion phecode
260.1 Cachexia Endocrine/metabolic 1.21 0.961 – 1.53 0.103 85 434 exclusion phecode
260.2 severe protein-calorie malnutrition Endocrine/metabolic 1.05 0.949 – 1.15 0.365 504 2601 exclusion phecode
260.22 Nutritional marasmus Endocrine/metabolic 1.02 0.878 – 1.19 0.78 197 956 exclusion phecode
260.3 Adult failure to thrive Endocrine/metabolic 1.07 0.923 – 1.24 0.365 215 1006 exclusion phecode
260.6 Anorexia Endocrine/metabolic 0.951 0.84 – 1.08 0.432 299 1455 exclusion phecode
260.7 Polyphagia Endocrine/metabolic 1.13 0.749 – 1.7 0.561 28 186 exclusion phecode
261 Vitamin deficiency Endocrine/metabolic 0.998 0.954 – 1.04 0.92 3082 5515 exclusion phecode
261.1 Vitamin A deficiency Endocrine/metabolic 1.16 0.782 – 1.71 0.466 33 147 exclusion phecode
261.2 Vitamin B-complex deficiencies Endocrine/metabolic 1.02 0.91 – 1.15 0.707 345 1474 exclusion phecode
261.4 Vitamin D deficiency Endocrine/metabolic 1 0.955 – 1.05 0.985 2923 5517 exclusion phecode
261.41 Rickets or osteomalacia Endocrine/metabolic 0.792 0.44 – 1.42 0.436 18 76 exclusion phecode
262 Mineral deficiency NEC Endocrine/metabolic 1.02 0.932 – 1.12 0.63 583 2068 exclusion phecode
263 Other nutritional deficiency Endocrine/metabolic 1.03 0.945 – 1.12 0.504 629 2700 exclusion phecode
264 Lack of normal physiological development Endocrine/metabolic 1.14 0.891 – 1.46 0.297 87 362 exclusion phecode
264.2 Failure to thrive (childhood) Endocrine/metabolic 1.07 0.779 – 1.48 0.66 40 188 exclusion phecode
264.9
Lack of normal physiological development
Lack of normal physiological development, unspecified
 Endocrine/metabolic 1.2 0.751 – 1.91 0.448 31 117 exclusion phecode
269 Proteinuria Endocrine/metabolic 1.11 1.03 – 1.19 0.00446 1040 3071 exclusion phecode
270
Disorders of protein plasma/amino-acid
Disorders of protein plasma/amino-acid transport and metabolism
 Endocrine/metabolic 0.974 0.873 – 1.09 0.637 393 1961 exclusion phecode
270.1 Disturbances of amino-acid transport Endocrine/metabolic 0.878 0.634 – 1.22 0.434 42 308 exclusion phecode
270.11
Disturbances of sulphur-bearing amino-acid
Disturbances of sulphur-bearing amino-acid metabolism
 Endocrine/metabolic 0.864 0.597 – 1.25 0.437 31 259 exclusion phecode
270.2 Disorders of amino-acid metabolism Endocrine/metabolic 0.761 0.551 – 1.05 0.0973 47 207 exclusion phecode
270.3 Disorders of plasma protein metabolism Endocrine/metabolic 1.02 0.899 – 1.15 0.792 321 1539 exclusion phecode
270.32 Paraproteinemia Endocrine/metabolic 1.06 0.897 – 1.25 0.492 173 844 exclusion phecode
270.33 Amyloidosis Endocrine/metabolic 1.67 1.07 – 2.6 0.0239 23 142 exclusion phecode
270.34 Alpha-1-antitrypsin deficiency Endocrine/metabolic 0.827 0.558 – 1.23 0.346 28 154 exclusion phecode
270.38
Other specified disorders of plasma protein
Other specified disorders of plasma protein metabolism
 Endocrine/metabolic 1.01 0.839 – 1.23 0.886 132 574 exclusion phecode
271
Disorders of carbohydrate transport and
Disorders of carbohydrate transport and metabolism
 Endocrine/metabolic 0.89 0.833 – 0.951 0.000521 1033 5694 exclusion phecode
271.3
Intestinal disaccharidase deficiencies and
Intestinal disaccharidase deficiencies and disaccharide malabsorption
 Endocrine/metabolic 0.896 0.838 – 0.958 0.00124 1004 5551 exclusion phecode
271.9
Other disorders of carbohydrate transport and
Other disorders of carbohydrate transport and metabolism
 Endocrine/metabolic 0.717 0.518 – 0.994 0.0456 39 229 exclusion phecode
272 Disorders of lipoid metabolism Endocrine/metabolic 1.38 1.31 – 1.45 3.73e-35 5679 3855 exclusion phecode
272.1 Hyperlipidemia Endocrine/metabolic 1.39 1.32 – 1.46 1.51e-35 5668 3853 exclusion phecode
272.11 Hypercholesterolemia Endocrine/metabolic 1.61 1.5 – 1.73 8.69e-37 2064 3096 exclusion phecode
272.12 Hyperglyceridemia Endocrine/metabolic 1.3 1.19 – 1.43 3.44e-08 712 1661 exclusion phecode
272.13 Mixed hyperlipidemia Endocrine/metabolic 1.51 1.41 – 1.63 1.79e-27 1744 2534 exclusion phecode
272.9 Unspecified disorder of lipoid metabolism Endocrine/metabolic 1.4 1.13 – 1.74 0.00215 125 427 exclusion phecode
274 Gout and other crystal arthropathies Endocrine/metabolic 1.05 0.98 – 1.12 0.169 1021 4780 exclusion phecode
274.1 Gout Endocrine/metabolic 1.05 0.981 – 1.13 0.154 977 4652 exclusion phecode
274.11 Gouty arthropathy Endocrine/metabolic 1.01 0.922 – 1.11 0.785 565 2505 exclusion phecode
274.2 Crystal arthropathies Endocrine/metabolic 0.988 0.772 – 1.26 0.925 82 410 exclusion phecode
274.21 Chondrocalcinosis Endocrine/metabolic 0.938 0.73 – 1.21 0.616 76 380 exclusion phecode
275 Disorders of mineral metabolism Endocrine/metabolic 1.05 0.994 – 1.11 0.0806 1628 7003 exclusion phecode
275.1 Disorders of iron metabolism Hematopoietic 0.922 0.722 – 1.18 0.517 84 443 exclusion phecode
275.11 Hereditary hemochromatosis Hematopoietic 0.785 0.542 – 1.14 0.2 34 222 exclusion phecode
275.2 Disorders of copper metabolism Endocrine/metabolic 0.902 0.596 – 1.36 0.624 30 137 exclusion phecode
275.3 Disorders of magnesium metabolism Endocrine/metabolic 1.14 1.03 – 1.26 0.0114 487 2346 exclusion phecode
275.5 Disorders of calcium/phosphorus metabolism Endocrine/metabolic 1.03 0.972 – 1.1 0.292 1242 5996 exclusion phecode
275.51 Hypocalcemia Endocrine/metabolic 1.01 0.891 – 1.14 0.91 305 1668 exclusion phecode
275.53 Disorders of phosphorus metabolism Endocrine/metabolic 1.04 0.95 – 1.14 0.403 580 2623 exclusion phecode
275.6 Hypercalcemia Endocrine/metabolic 1.04 0.949 – 1.13 0.423 585 3003 exclusion phecode
276
Disorders of fluid, electrolyte, and acid-base
Disorders of fluid, electrolyte, and acid-base balance
 Endocrine/metabolic 1.04 0.995 – 1.09 0.0802 3458 6053 exclusion phecode
276.1 Electrolyte imbalance Endocrine/metabolic 1.04 0.995 – 1.09 0.0802 2564 5636 exclusion phecode
276.11 Hyperosmolality and/or hypernatremia Endocrine/metabolic 1.03 0.901 – 1.18 0.653 262 1017 exclusion phecode
276.12 Hyposmolality and/or hyponatremia Endocrine/metabolic 1.06 0.99 – 1.13 0.0968 1050 3848 exclusion phecode
276.13 Hyperpotassemia Endocrine/metabolic 1.06 0.994 – 1.12 0.0753 1407 4299 exclusion phecode
276.14 Hypopotassemia Endocrine/metabolic 1.02 0.951 – 1.1 0.523 865 3516 exclusion phecode
276.4 Acid-base balance disorder Endocrine/metabolic 1.08 1 – 1.15 0.0433 999 3475 exclusion phecode
276.41 Acidosis Endocrine/metabolic 1.06 0.981 – 1.14 0.139 871 3067 exclusion phecode
276.42 Alkalosis Endocrine/metabolic 1.15 0.992 – 1.32 0.0636 222 885 exclusion phecode
276.5 Hypovolemia Endocrine/metabolic 1.06 1.01 – 1.12 0.0259 1733 5592 exclusion phecode
276.6 Fluid overload Endocrine/metabolic 1.02 0.941 – 1.11 0.624 777 2360 exclusion phecode
276.8 Polydipsia Endocrine/metabolic 1.03 0.753 – 1.42 0.838 48 243 exclusion phecode
277 Other disorders of metabolism Endocrine/metabolic 1.03 0.98 – 1.09 0.215 1698 6591 exclusion phecode
277.2
Other disorders of purine and pyrimidine
Other disorders of purine and pyrimidine metabolism
 Endocrine/metabolic 1.06 0.905 – 1.24 0.467 206 1102 exclusion phecode
277.4 Disorders of bilirubin excretion Endocrine/metabolic 0.935 0.824 – 1.06 0.303 301 1459 exclusion phecode
277.5 Other disorders of lipoid metabolism Endocrine/metabolic 0.963 0.868 – 1.07 0.48 434 2099 exclusion phecode
277.51 Lipoprotein disorders Endocrine/metabolic 0.963 0.858 – 1.08 0.519 364 1753 exclusion phecode
277.7 Dysmetabolic syndrome X Endocrine/metabolic 1.07 0.97 – 1.19 0.173 478 2058 exclusion phecode
278 Overweight, obesity and other hyperalimentation Endocrine/metabolic 0.983 0.943 – 1.02 0.401 5231 4434 exclusion phecode
278.1 Obesity Endocrine/metabolic 0.974 0.934 – 1.02 0.219 4572 4431 exclusion phecode
278.11 Morbid obesity Endocrine/metabolic 0.973 0.925 – 1.02 0.291 2451 4374 exclusion phecode
278.3 Localized adiposity Endocrine/metabolic 0.935 0.77 – 1.14 0.499 130 546 exclusion phecode
278.4 Abnormal weight gain Endocrine/metabolic 0.991 0.917 – 1.07 0.83 844 2845 exclusion phecode
279 Disorders involving the immune mechanism Endocrine/metabolic 1.05 0.988 – 1.12 0.111 1247 5013 exclusion phecode
279.1 Immunity deficiency Endocrine/metabolic 1.1 1 – 1.22 0.0486 527 2081 exclusion phecode
279.11 Deficiency of humoral immunity Endocrine/metabolic 1.13 0.927 – 1.37 0.229 128 636 exclusion phecode
279.2 Autoimmune disease NEC Endocrine/metabolic 1.1 0.962 – 1.25 0.168 270 1441 exclusion phecode
279.7 Other immunological findings Endocrine/metabolic 1.03 0.98 – 1.08 0.248 2058 6405 exclusion phecode
279.8
Other specified disorders involving the immune
Other specified disorders involving the immune mechanism
 Endocrine/metabolic 1.1 0.95 – 1.27 0.208 231 1146 exclusion phecode
280 Iron deficiency anemias Hematopoietic 1.1 1.04 – 1.16 0.000847 1997 4825 exclusion phecode
280.1
Iron deficiency anemias, unspecified or not due
Iron deficiency anemias, unspecified or not due to blood loss
 Hematopoietic 1.09 1.03 – 1.15 0.00147 1938 4789 exclusion phecode
280.2
Iron deficiency anemia secondary to blood loss
Iron deficiency anemia secondary to blood loss (chronic)
 Hematopoietic 1.07 0.982 – 1.16 0.125 781 2762 exclusion phecode
281 Other deficiency anemia Hematopoietic 1.09 0.948 – 1.26 0.219 240 834 exclusion phecode
281.1 Megaloblastic anemia Hematopoietic 1.11 0.902 – 1.38 0.316 108 422 exclusion phecode
281.11 Pernicious anemia Hematopoietic 1.1 0.794 – 1.52 0.569 51 199 exclusion phecode
281.12 Other vitamin B12 deficiency anemia Hematopoietic 1.16 0.9 – 1.49 0.255 73 310 exclusion phecode
281.9 Deficiency anemias Hematopoietic 1.09 0.9 – 1.31 0.383 149 451 exclusion phecode
282 Hereditary hemolytic anemias Hematopoietic 0.929 0.763 – 1.13 0.466 134 557 exclusion phecode
282.8 Other hemoglobinopathies Hematopoietic 0.989 0.781 – 1.25 0.928 91 414 exclusion phecode
282.9 Other hereditary hemolytic anemias Hematopoietic 1.07 0.834 – 1.36 0.609 86 342 exclusion phecode
283 Acquired hemolytic anemias Hematopoietic 0.839 0.637 – 1.1 0.208 77 286 exclusion phecode
283.1 Autoimmune hemolytic anemias Hematopoietic 0.626 0.407 – 0.962 0.0327 30 122 exclusion phecode
284 Aplastic anemia Hematopoietic 1.15 1.01 – 1.31 0.0378 314 1151 exclusion phecode
284.1 Pancytopenia Hematopoietic 1.18 1.02 – 1.36 0.0231 272 1006 exclusion phecode
285 Other anemias Hematopoietic 1.07 1.03 – 1.12 0.00123 4012 5235 exclusion phecode
285.1 Acute posthemorrhagic anemia Hematopoietic 1.12 1.05 – 1.2 0.000736 1210 4141 exclusion phecode
285.2 Anemia of chronic disease Hematopoietic 1.11 1.03 – 1.19 0.0075 957 3176 exclusion phecode
285.21 Anemia in chronic kidney disease Hematopoietic 1.09 0.985 – 1.2 0.0957 589 1688 exclusion phecode
285.22 Anemia in neoplastic disease Hematopoietic 0.992 0.842 – 1.17 0.921 179 955 exclusion phecode
286 Coagulation defects Hematopoietic 1.09 1.02 – 1.15 0.00684 1401 5809 exclusion phecode
286.1 Congenital coagulation defects Hematopoietic 0.921 0.711 – 1.19 0.535 71 465 exclusion phecode
286.11 Von willebrand's disease Hematopoietic 0.799 0.5 – 1.28 0.347 19 157 exclusion phecode
286.12
Congenital deficiency of other clotting factors
Congenital deficiency of other clotting factors (including factor VII)
 Hematopoietic 0.971 0.684 – 1.38 0.871 36 250 exclusion phecode
286.2
Encounter for long-term (current) use of
Encounter for long-term (current) use of anticoagulants
 Hematopoietic 1.09 1.02 – 1.16 0.00641 1406 4555 exclusion phecode
286.3
Coagulation defects complicating pregnancy or
Coagulation defects complicating pregnancy or postpartum
 Hematopoietic 0.76 0.529 – 1.09 0.137 33 216 exclusion phecode
286.4 Acquired coagulation factor deficiency Hematopoietic 0.94 0.761 – 1.16 0.561 118 492 exclusion phecode
286.5
Hemorrhagic disorder due to intrinsic
Hemorrhagic disorder due to intrinsic circulating anticoagulants
 Hematopoietic 1.17 0.88 – 1.55 0.284 61 269 exclusion phecode
286.6 Defibrination syndrome Hematopoietic 1.07 0.998 – 1.16 0.0555 892 4540 exclusion phecode
286.7 Other and unspecified coagulation defects Hematopoietic 1.08 1.01 – 1.15 0.0284 1077 5172 exclusion phecode
286.8 Hypercoagulable state Hematopoietic 0.994 0.867 – 1.14 0.934 244 1533 exclusion phecode
286.81 Primary hypercoagulable state Hematopoietic 0.966 0.841 – 1.11 0.628 234 1475 exclusion phecode
286.9 Abnormal coagulation profile Hematopoietic 1.09 0.99 – 1.2 0.0782 557 2114 exclusion phecode
287 Purpura and other hemorrhagic conditions Hematopoietic 1.13 1.06 – 1.2 0.000199 1326 5057 exclusion phecode
287.1 Spontaneous ecchymoses Hematopoietic 1.32 1.03 – 1.69 0.0282 82 401 exclusion phecode
287.3 Thrombocytopenia Hematopoietic 1.14 1.07 – 1.22 6.45e-05 1203 4696 exclusion phecode
287.31 Primary thrombocytopenia Hematopoietic 1.19 1.01 – 1.41 0.0328 189 1070 exclusion phecode
287.32 Secondary thrombocytopenia Hematopoietic 1.15 0.987 – 1.34 0.0729 208 1015 exclusion phecode
287.4 Qualitative platelet defects Hematopoietic 1.12 0.772 – 1.64 0.542 39 205 exclusion phecode
288 Diseases of white blood cells Hematopoietic 1.01 0.961 – 1.07 0.631 1829 6382 exclusion phecode
288.1 Decreased white blood cell count Hematopoietic 1.02 0.934 – 1.12 0.613 572 2808 exclusion phecode
288.11 Neutropenia Hematopoietic 1.01 0.898 – 1.13 0.904 378 1937 exclusion phecode
288.2 Elevated white blood cell count Hematopoietic 1.01 0.956 – 1.07 0.706 1606 6166 exclusion phecode
288.3 Eosinophilia Hematopoietic 1.12 0.849 – 1.48 0.422 48 359 exclusion phecode
289 Other diseases of blood and blood-forming organs Hematopoietic 1.03 0.949 – 1.12 0.467 713 3255 exclusion phecode
289.3
Personal history of diseases of blood and
Personal history of diseases of blood and blood-forming organs
 Hematopoietic 1.1 0.974 – 1.24 0.125 358 1665 exclusion phecode
289.4 Lymphadenitis Hematopoietic 1.02 0.953 – 1.09 0.605 1100 6068 exclusion phecode
289.5 Diseases of spleen Hematopoietic 1.05 0.885 – 1.25 0.571 168 754 exclusion phecode
289.8 Polycythemia, secondary Hematopoietic 0.993 0.817 – 1.21 0.942 126 546 exclusion phecode
289.9 Abnormality of red blood cells Hematopoietic 0.976 0.833 – 1.14 0.764 181 808 exclusion phecode
290
Delirium dementia and amnestic and other
Delirium dementia and amnestic and other cognitive disorders
 Mental Disorders 1.03 0.938 – 1.13 0.53 554 2261 exclusion phecode
290.1 Dementias Mental Disorders 1 0.864 – 1.16 0.996 222 1011 exclusion phecode
290.11 Alzheimer's disease Mental Disorders 1.32 1.01 – 1.74 0.0451 63 297 exclusion phecode
290.12 Dementia with cerebral degenerations Mental Disorders 1.04 0.743 – 1.44 0.838 46 162 exclusion phecode
290.13 Senile dementia Mental Disorders 0.924 0.769 – 1.11 0.395 145 620 exclusion phecode
290.16 Vascular dementia Mental Disorders 1.02 0.717 – 1.45 0.909 42 157 exclusion phecode
290.2 Delirium due to conditions classified elsewhere Mental Disorders 1.05 0.933 – 1.18 0.408 338 1417 exclusion phecode
290.3
Other persistent mental disorders due to
Other persistent mental disorders due to conditions classified elsewhere
 Mental Disorders 1.02 0.905 – 1.15 0.769 340 1787 exclusion phecode
291
Other specified nonpsychotic and/or transient
Other specified nonpsychotic and/or transient mental disorders
 Mental Disorders 0.998 0.931 – 1.07 0.945 991 4769 exclusion phecode
291.1
Transient mental disorders due to conditions
Transient mental disorders due to conditions classified elsewhere
 Mental Disorders 1.03 0.788 – 1.34 0.846 64 389 exclusion phecode
291.4
Specific nonpsychotic mental disorders due to
Specific nonpsychotic mental disorders due to brain damage
 Mental Disorders 1 0.849 – 1.18 0.999 173 924 exclusion phecode
291.8 Alteration of consciousness Mental Disorders 1 0.927 – 1.08 0.973 808 3871 exclusion phecode
292 Neurological disorders Mental Disorders 0.995 0.946 – 1.05 0.844 2012 6897 exclusion phecode
292.1 Aphasia/speech disturbance Mental Disorders 0.985 0.904 – 1.07 0.735 596 3623 exclusion phecode
292.11 Aphasia Mental Disorders 0.975 0.842 – 1.13 0.739 215 1193 exclusion phecode
292.12 Symbolic dysfunction Mental Disorders 0.932 0.704 – 1.24 0.625 50 354 exclusion phecode
292.2 Mild cognitive impairment Mental Disorders 1.02 0.869 – 1.2 0.794 188 757 exclusion phecode
292.3 Memory loss Mental Disorders 0.97 0.895 – 1.05 0.462 719 3457 exclusion phecode
292.4 Altered mental status Mental Disorders 1 0.934 – 1.07 0.998 1049 4350 exclusion phecode
292.5 Transient alteration of awareness Mental Disorders 1 0.853 – 1.18 0.987 184 887 exclusion phecode
292.6 Hallucinations Mental Disorders 0.803 0.647 – 0.998 0.0482 93 401 exclusion phecode
293 Symptoms involving head and neck Mental Disorders 0.927 0.774 – 1.11 0.408 135 861 exclusion phecode
293.1
Swelling, mass, or lump in head and neck
Swelling, mass, or lump in head and neck [Space-occupying lesion, intracranial NOS]
 Mental Disorders 1.01 0.944 – 1.07 0.847 1093 7651 exclusion phecode
295 Schizophrenia and other psychotic disorders Mental Disorders 0.951 0.844 – 1.07 0.412 371 1210 exclusion phecode
295.1 Schizophrenia Mental Disorders 1.16 0.81 – 1.66 0.417 38 211 exclusion phecode
295.2 Paranoid disorders Mental Disorders 0.908 0.639 – 1.29 0.591 46 155 exclusion phecode
295.3 Psychosis Mental Disorders 0.968 0.849 – 1.1 0.631 320 1037 exclusion phecode
296 Mood disorders Mental Disorders 0.978 0.931 – 1.03 0.377 4100 2877 exclusion phecode
296.1 Bipolar Mental Disorders 1.03 0.914 – 1.15 0.673 384 1539 exclusion phecode
296.2 Depression Mental Disorders 0.98 0.932 – 1.03 0.429 3956 2877 exclusion phecode
296.22 Major depressive disorder Mental Disorders 0.972 0.924 – 1.02 0.277 3663 2874 exclusion phecode
297 Suicidal ideation or attempt Mental Disorders 0.959 0.85 – 1.08 0.491 361 1257 exclusion phecode
297.1 Suicidal ideation Mental Disorders 0.999 0.872 – 1.14 0.984 289 1042 exclusion phecode
297.2 Suicide or self-inflicted injury Mental Disorders 0.956 0.766 – 1.19 0.692 104 364 exclusion phecode
300 Anxiety disorders Mental Disorders 0.974 0.926 – 1.02 0.295 4064 2877 exclusion phecode
300.1 Anxiety disorder Mental Disorders 0.974 0.926 – 1.03 0.317 3817 2880 exclusion phecode
300.11 Generalized anxiety disorder Mental Disorders 0.949 0.891 – 1.01 0.102 1751 2820 exclusion phecode
300.12 Agorophobia, social phobia, and panic disorder Mental Disorders 0.997 0.896 – 1.11 0.961 457 1569 exclusion phecode
300.13 Phobia Mental Disorders 0.892 0.787 – 1.01 0.0723 344 1373 exclusion phecode
300.3 Obsessive-compulsive disorders Mental Disorders 0.828 0.674 – 1.02 0.0728 110 509 exclusion phecode
300.4 Dysthymic disorder Mental Disorders 0.942 0.869 – 1.02 0.146 849 2320 exclusion phecode
300.8 Acute reaction to stress Mental Disorders 0.912 0.78 – 1.07 0.253 198 767 exclusion phecode
300.9 Posttraumatic stress disorder Mental Disorders 0.998 0.858 – 1.16 0.98 224 1086 exclusion phecode
301 Personality disorders Mental Disorders 0.971 0.81 – 1.16 0.752 153 656 exclusion phecode
301.2 Antisocial/borderline personality disorder Mental Disorders 0.983 0.765 – 1.26 0.892 77 352 exclusion phecode
302 Sexual and gender identity disorders Mental Disorders 0.932 0.866 – 1 0.0556 1300 2056 exclusion phecode
302.1 Decreased libido Mental Disorders 0.772 0.653 – 0.912 0.00234 183 781 exclusion phecode
303 Psychogenic and somatoform disorders Mental Disorders 0.951 0.898 – 1.01 0.0797 2417 2780 exclusion phecode
303.1 Dissociative disorder Mental Disorders 0.975 0.707 – 1.34 0.876 42 246 exclusion phecode
303.3 Psychogenic disorder Mental Disorders 0.946 0.894 – 1 0.0593 2332 2753 exclusion phecode
303.31
Gastrointestinal malfunction arising from
Gastrointestinal malfunction arising from mental factors
 Mental Disorders 0.903 0.756 – 1.08 0.259 152 713 exclusion phecode
303.4 Somatoform disorder Mental Disorders 0.997 0.881 – 1.13 0.962 308 1497 exclusion phecode
304 Adjustment reaction Mental Disorders 0.924 0.863 – 0.989 0.022 1351 2839 exclusion phecode
305.2 Eating disorder Mental Disorders 0.894 0.794 – 1.01 0.0642 354 1266 exclusion phecode
306 Other mental disorder Mental Disorders 0.954 0.87 – 1.05 0.318 632 1995 exclusion phecode
306.1 Mental disorders durring/after pregnancy Mental Disorders 1.16 0.969 – 1.39 0.107 186 521 exclusion phecode
306.9 Tension headache Mental Disorders 0.916 0.795 – 1.06 0.227 254 1119 exclusion phecode
312 Conduct disorders Mental Disorders 0.897 0.713 – 1.13 0.352 98 469 exclusion phecode
312.3 Impulse control disorder Mental Disorders 0.795 0.532 – 1.19 0.264 26 172 exclusion phecode
313 Pervasive developmental disorders Mental Disorders 0.946 0.852 – 1.05 0.296 437 2805 exclusion phecode
313.1 Attention deficit hyperactivity disorder Mental Disorders 0.944 0.844 – 1.06 0.31 378 2488 exclusion phecode
313.2 Tics and stuttering Mental Disorders 0.768 0.509 – 1.16 0.21 26 122 exclusion phecode
313.3 Autism Mental Disorders 1.12 0.676 – 1.85 0.662 23 106 exclusion phecode
315 Develomental delays and disorders Mental Disorders 1.06 0.933 – 1.21 0.36 269 1348 exclusion phecode
315.1 Learning disorder Mental Disorders 0.948 0.661 – 1.36 0.773 37 171 exclusion phecode
315.2 Speech and language disorder Mental Disorders 1.07 0.846 – 1.36 0.566 82 448 exclusion phecode
316 Substance addiction and disorders Mental Disorders 1.05 0.978 – 1.12 0.188 1043 5713 exclusion phecode
316.1 Polyneuropathy due to drugs Mental Disorders 1 0.836 – 1.2 0.986 141 1014 exclusion phecode
317 Alcohol-related disorders Mental Disorders 1.07 0.994 – 1.16 0.0707 767 4157 exclusion phecode
317.1 Alcoholism Mental Disorders 1.05 0.969 – 1.15 0.215 638 3533 exclusion phecode
317.11 Alcoholic liver damage Mental Disorders 1.02 0.86 – 1.2 0.844 172 772 exclusion phecode
318 Tobacco use disorder Mental Disorders 1.04 0.995 – 1.1 0.0813 2393 6376 exclusion phecode
320 Meningitis Neurological 1.15 0.936 – 1.41 0.186 103 723 exclusion phecode
323 Encephalitis Neurological 0.812 0.615 – 1.07 0.143 57 377 exclusion phecode
323.8 Encephalitis, non-infectious Neurological 0.856 0.643 – 1.14 0.286 51 307 exclusion phecode
324 Other CNS infection and poliomyelitis Neurological 1.04 0.819 – 1.31 0.759 73 594 exclusion phecode
325
Phlebitis and thrombophlebitis of intracranial
Phlebitis and thrombophlebitis of intracranial venous sinuses
 Neurological 0.828 0.506 – 1.36 0.453 16 120 exclusion phecode
327 Sleep disorders Neurological 0.987 0.947 – 1.03 0.534 4707 4911 exclusion phecode
327.1 Hypersomnia Neurological 0.974 0.902 – 1.05 0.498 836 3183 exclusion phecode
327.3 Sleep apnea Neurological 0.998 0.954 – 1.04 0.925 3462 4848 exclusion phecode
327.31 Central/nonobstroctive sleep apnea Neurological 1.05 0.907 – 1.22 0.503 222 927 exclusion phecode
327.32 Obstructive sleep apnea Neurological 0.986 0.941 – 1.03 0.547 3078 4752 exclusion phecode
327.4 Insomnia Neurological 0.963 0.913 – 1.01 0.156 2090 4805 exclusion phecode
327.41 Organic or persistent insomnia Neurological 0.902 0.818 – 0.995 0.0401 529 2041 exclusion phecode
327.5 Parasomnia Neurological 0.985 0.859 – 1.13 0.833 265 1049 exclusion phecode
327.6 Circadian rhythm sleep disorder Neurological 0.893 0.73 – 1.09 0.271 127 547 exclusion phecode
327.7 Sleep related movement disorders Neurological 0.911 0.835 – 0.993 0.0334 644 2781 exclusion phecode
327.71 Restless legs syndrome Neurological 0.908 0.828 – 0.996 0.0417 550 2452 exclusion phecode
327.72 Sleep related leg cramps Neurological 1.14 0.772 – 1.69 0.507 38 143 exclusion phecode
331 Other cerebral degenerations Neurological 1.04 0.9 – 1.2 0.603 244 1390 exclusion phecode
331.1 Hydrocephalus Neurological 1.07 0.793 – 1.44 0.665 45 465 exclusion phecode
331.9 Cerebral degeneration, unspecified Neurological 0.985 0.836 – 1.16 0.858 196 855 exclusion phecode
332 Parkinson's disease Neurological 0.809 0.674 – 0.972 0.0234 137 829 exclusion phecode
333
Extrapyramidal disease and abnormal movement
Extrapyramidal disease and abnormal movement disorders
 Neurological 0.908 0.848 – 0.972 0.00559 989 5040 exclusion phecode
333.1 Essential tremor Neurological 0.91 0.803 – 1.03 0.142 276 1451 exclusion phecode
333.2 Myoclonus Neurological 1.2 0.927 – 1.57 0.164 69 299 exclusion phecode
333.4 Torsion dystonia Neurological 0.915 0.734 – 1.14 0.433 96 615 exclusion phecode
333.8 Other degenerative diseases of the basal ganglia Neurological 1.03 0.719 – 1.47 0.883 44 201 exclusion phecode
334 Degenerative disease of the spinal cord Neurological 0.877 0.772 – 0.995 0.0422 260 1858 exclusion phecode
334.1 Spinocerebellar disease Neurological 0.811 0.543 – 1.21 0.305 34 161 exclusion phecode
334.2 Anterior horn cell disease Neurological 0.7 0.486 – 1.01 0.0556 26 223 exclusion phecode
334.21 Amyotrophic Lateral Sclerosis Neurological 0.825 0.548 – 1.24 0.357 20 135 exclusion phecode
335 Multiple sclerosis Neurological 0.947 0.77 – 1.16 0.602 98 674 exclusion phecode
337 Disorders of the autonomic nervous system Neurological 1 0.896 – 1.12 0.969 358 1845 exclusion phecode
337.1 Peripheral autonomic neuropathy Neurological 0.993 0.863 – 1.14 0.926 248 1126 exclusion phecode
338 Pain Neurological 0.972 0.933 – 1.01 0.174 5169 4494 exclusion phecode
338.1 Acute pain Neurological 0.977 0.933 – 1.02 0.302 3716 4460 exclusion phecode
338.2 Chronic pain Neurological 0.968 0.924 – 1.01 0.162 3366 4466 exclusion phecode
339 Other headache syndromes Neurological 0.979 0.934 – 1.03 0.37 2691 6364 exclusion phecode
340 Migraine Neurological 0.941 0.891 – 0.994 0.0293 1799 5505 exclusion phecode
340.1 Migrain with aura Neurological 0.964 0.899 – 1.03 0.302 1019 4148 exclusion phecode
341
Other demyelinating diseases of central nervous
Other demyelinating diseases of central nervous system
 Neurological 1.08 0.771 – 1.5 0.668 45 254 exclusion phecode
342 Hemiplegia Neurological 0.993 0.844 – 1.17 0.931 177 875 exclusion phecode
343 Infantile cerebral palsy Neurological 1.17 0.721 – 1.89 0.528 19 136 exclusion phecode
344 Other paralytic syndromes Neurological 1.04 0.9 – 1.21 0.576 200 1132 exclusion phecode
345 Epilepsy, recurrent seizures, convulsions Neurological 0.983 0.907 – 1.07 0.67 669 4596 exclusion phecode
345.1 Epilepsy Neurological 0.974 0.843 – 1.13 0.725 209 1332 exclusion phecode
345.11 Generalized convulsive epilepsy Neurological 1.06 0.808 – 1.38 0.693 60 399 exclusion phecode
345.12 Partial epilepsy Neurological 0.931 0.784 – 1.11 0.415 145 946 exclusion phecode
345.3 Convulsions Neurological 0.982 0.904 – 1.07 0.665 637 4339 exclusion phecode
346
Abnormal findings on study of brain and/or
Abnormal findings on study of brain and/or nervous system
 Neurological 0.736 0.555 – 0.975 0.033 54 332 exclusion phecode
346.1
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of skull and head
 Neurological 0.971 0.881 – 1.07 0.553 467 2767 exclusion phecode
346.2
Nonspecific abnormal results of function study
Nonspecific abnormal results of function study of brain and central nervous system
 Neurological 0.768 0.537 – 1.1 0.149 38 210 exclusion phecode
346.3
Nonspecific abnormal findings in cerebrospinal
Nonspecific abnormal findings in cerebrospinal fluid
 Neurological 0.814 0.554 – 1.2 0.297 29 186 exclusion phecode
347 Cataplexy and narcolepsy Neurological 1.23 0.809 – 1.88 0.33 25 213 exclusion phecode
348 Other conditions of brain Neurological 0.952 0.869 – 1.04 0.295 530 3263 exclusion phecode
348.2 Cerebral edema and compression of brain Neurological 0.938 0.805 – 1.09 0.416 169 1532 exclusion phecode
348.4 Cerebral cysts Neurological 0.755 0.566 – 1.01 0.0554 49 416 exclusion phecode
348.7 Coma Neurological 1.23 0.952 – 1.59 0.113 79 449 exclusion phecode
348.8 Encephalopathy, not elsewhere classified Neurological 1.03 0.915 – 1.16 0.638 349 1621 exclusion phecode
348.9 Other conditions of brain, NOS Neurological 0.995 0.914 – 1.08 0.905 610 4145 exclusion phecode
349
Other and unspecified disorders of the nervous
Other and unspecified disorders of the nervous system
 Neurological 0.961 0.845 – 1.09 0.54 275 1634 exclusion phecode
350 Abnormal movement Neurological 0.987 0.94 – 1.04 0.587 2326 6954 exclusion phecode
350.1 Abnormal involuntary movements Neurological 0.978 0.919 – 1.04 0.496 1167 5629 exclusion phecode
350.2 Abnormality of gait Neurological 0.967 0.912 – 1.03 0.265 1460 5510 exclusion phecode
350.3 Lack of coordination Neurological 1.04 0.927 – 1.16 0.525 373 1959 exclusion phecode
350.5 Abnormal reflex Neurological 0.963 0.732 – 1.27 0.786 66 360 exclusion phecode
350.6 Disturbances of sensation of smell and taste Neurological 0.97 0.816 – 1.15 0.73 134 1038 exclusion phecode
351 Other peripheral nerve disorders Neurological 0.939 0.895 – 0.984 0.00884 2515 6009 exclusion phecode
352 Disorders of other cranial nerves Neurological 0.958 0.856 – 1.07 0.46 346 2885 exclusion phecode
352.1 Trigeminal nerve disorders [CN5] Neurological 0.878 0.729 – 1.06 0.171 131 850 exclusion phecode
352.2 Facial nerve disorders [CN7] Neurological 0.948 0.811 – 1.11 0.504 181 1334 exclusion phecode
353 Nerve root and plexus disorders Neurological 0.964 0.907 – 1.02 0.231 1337 5759 exclusion phecode
353.1 Nerve plexus lesions Neurological 0.904 0.719 – 1.14 0.384 89 686 exclusion phecode
353.2 Nerve root lesions Neurological 0.803 0.577 – 1.12 0.193 37 250 exclusion phecode
355 Complex regional/central pain syndrome Neurological 0.993 0.833 – 1.18 0.938 139 904 exclusion phecode
355.1 Chronic pain syndrome Neurological 0.955 0.839 – 1.09 0.487 291 1467 exclusion phecode
356 Hereditary and idiopathic peripheral neuropathy Neurological 0.992 0.925 – 1.06 0.812 1010 4136 exclusion phecode
357 Inflammatory and toxic neuropathy Neurological 1.01 0.949 – 1.07 0.807 1360 5669 exclusion phecode
358 Myoneural disorders Neurological 0.962 0.864 – 1.07 0.477 387 2283 exclusion phecode
358.1 Myasthenia gravis Neurological 0.876 0.544 – 1.41 0.587 23 197 exclusion phecode
359 Muscular dystrophies and other myopathies Neurological 0.985 0.885 – 1.1 0.786 378 2177 exclusion phecode
359.1 Muscular dystrophies Neurological 0.702 0.376 – 1.31 0.266 13 122 exclusion phecode
359.2 Myopathy Neurological 0.982 0.882 – 1.09 0.745 370 2102 exclusion phecode
360 Disorders of the globe Sense Organs 0.863 0.656 – 1.14 0.295 62 306 exclusion phecode
360.2 Progressive myopia Sense Organs 1.03 0.715 – 1.49 0.86 32 141 exclusion phecode
361 Retinal detachments and defects Sense Organs 0.848 0.75 – 0.959 0.00871 295 1588 exclusion phecode
361.1 Retinal detachment with retinal defect Sense Organs 0.936 0.775 – 1.13 0.496 120 662 exclusion phecode
362 Other retinal disorders Sense Organs 0.952 0.897 – 1.01 0.0999 1607 4119 exclusion phecode
362.2
Degeneration of macula and posterior pole of
Degeneration of macula and posterior pole of retina
 Sense Organs 0.966 0.896 – 1.04 0.364 941 2928 exclusion phecode
362.21 Macular degeneration, dry Sense Organs 0.898 0.765 – 1.05 0.19 193 676 exclusion phecode
362.22 Macular degeneration, wet Sense Organs 0.846 0.649 – 1.1 0.217 63 275 exclusion phecode
362.23 Cystoid macular degeneration of retina Sense Organs 1.01 0.862 – 1.19 0.893 180 807 exclusion phecode
362.26 Macular puckering of retina Sense Organs 0.994 0.897 – 1.1 0.902 453 1856 exclusion phecode
362.27 Drusen (degenerative) of retina Sense Organs 0.869 0.754 – 1 0.0536 217 972 exclusion phecode
362.29 Macular degeneration (senile) of retina NOS Sense Organs 0.946 0.874 – 1.02 0.173 814 2690 exclusion phecode
362.3 Other nondiabetic retinopathy Sense Organs 0.904 0.822 – 0.995 0.0392 508 1857 exclusion phecode
362.31 Separation of retinal layers Sense Organs 0.862 0.728 – 1.02 0.0838 157 925 exclusion phecode
362.4 Retinal vascular changes and abnomalities Sense Organs 0.918 0.814 – 1.03 0.157 320 1339 exclusion phecode
362.6 Peripheral retinal degenerations Sense Organs 0.972 0.832 – 1.14 0.723 170 843 exclusion phecode
362.7 Hereditary retinal dystrophies Sense Organs 1.01 0.807 – 1.27 0.919 88 453 exclusion phecode
362.8 Retinal hemorrhage/ischemia Sense Organs 0.856 0.701 – 1.05 0.127 103 640 exclusion phecode
362.9 Retinal edema Sense Organs 0.985 0.837 – 1.16 0.861 177 780 exclusion phecode
363
Chorioretinal inflammations, scars, and other
Chorioretinal inflammations, scars, and other disorders of choroid
 Sense Organs 0.819 0.704 – 0.953 0.01 190 1001 exclusion phecode
363.3 Chorioretinal scars Sense Organs 0.822 0.689 – 0.98 0.0293 138 698 exclusion phecode
364 Corneal opacity and other disorders of cornea Sense Organs 0.933 0.839 – 1.04 0.196 419 2214 exclusion phecode
364.1 Corneal opacity Sense Organs 0.837 0.702 – 0.998 0.0472 151 858 exclusion phecode
364.2 Corneal edema Sense Organs 0.765 0.559 – 1.05 0.0927 55 284 exclusion phecode
364.4 Corneal degenerations Sense Organs 0.848 0.708 – 1.01 0.0715 148 903 exclusion phecode
364.41 Keratoconus Sense Organs 0.833 0.551 – 1.26 0.386 29 178 exclusion phecode
364.5 Corneal dystrophy Sense Organs 1.04 0.89 – 1.21 0.629 188 967 exclusion phecode
364.51 Fuchs' dystrophy Sense Organs 0.963 0.777 – 1.19 0.733 92 560 exclusion phecode
364.9 Cornea replaced by transplant Sense Organs 0.934 0.649 – 1.34 0.711 33 198 exclusion phecode
365 Glaucoma Sense Organs 0.961 0.897 – 1.03 0.258 1000 4103 exclusion phecode
365.1 Open-angle glaucoma Sense Organs 0.987 0.875 – 1.11 0.837 313 1412 exclusion phecode
365.11 Primary open angle glaucoma Sense Organs 1.09 0.926 – 1.27 0.309 177 848 exclusion phecode
365.2 Primary angle-closure glaucoma Sense Organs 1.03 0.841 – 1.27 0.747 107 546 exclusion phecode
366 Cataract Sense Organs 1.01 0.957 – 1.06 0.82 3355 4691 exclusion phecode
366.1 Nonsenile Cataract Sense Organs 0.995 0.792 – 1.25 0.968 88 388 exclusion phecode
366.2 Senile cataract Sense Organs 0.989 0.937 – 1.04 0.682 2468 4156 exclusion phecode
367
Disorders of refraction and accommodation
Disorders of refraction and accommodation; blindness and low vision
 Sense Organs 0.95 0.91 – 0.99 0.016 3640 6032 exclusion phecode
367.1 Myopia Sense Organs 0.955 0.907 – 1.01 0.077 2059 5613 exclusion phecode
367.2 Astigmatism Sense Organs 0.934 0.884 – 0.987 0.0155 1691 5352 exclusion phecode
367.8 Hypermetropia Sense Organs 0.888 0.821 – 0.96 0.00297 784 3254 exclusion phecode
367.9 Blindness and low vision Sense Organs 0.938 0.848 – 1.04 0.213 495 2209 exclusion phecode
368 Visual disturbances Sense Organs 1 0.955 – 1.06 0.862 2006 7405 exclusion phecode
368.1 Amblyopia Sense Organs 1.07 0.916 – 1.24 0.412 217 1410 exclusion phecode
368.2 Diplopia and disorders of binocular vision Sense Organs 0.924 0.83 – 1.03 0.152 386 2220 exclusion phecode
368.3 Anisometropia Sense Organs 0.829 0.659 – 1.04 0.107 87 471 exclusion phecode
368.4 Visual field defects Sense Organs 0.956 0.863 – 1.06 0.389 432 2219 exclusion phecode
368.9 Subjective visual disturbances Sense Organs 0.945 0.85 – 1.05 0.296 403 2198 exclusion phecode
368.91 Psychophysical visual disturbances Sense Organs 0.849 0.615 – 1.17 0.322 51 228 exclusion phecode
369 Infection of the eye Sense Organs 0.967 0.908 – 1.03 0.3 1240 4946 exclusion phecode
369.2 Eye infection, viral Sense Organs 1.09 0.92 – 1.29 0.326 178 990 exclusion phecode
369.5 Conjunctivitis, infectious Sense Organs 0.959 0.897 – 1.02 0.215 1082 4509 exclusion phecode
370 Keratitis Sense Organs 0.971 0.883 – 1.07 0.552 517 2507 exclusion phecode
370.1 Corneal ulcer Sense Organs 0.973 0.767 – 1.24 0.823 84 500 exclusion phecode
370.2 Superficial keratitis Sense Organs 0.958 0.826 – 1.11 0.577 213 1020 exclusion phecode
370.3 Keratoconjunctivitis Sense Organs 0.928 0.806 – 1.07 0.297 241 1169 exclusion phecode
370.31 Keratoconjunctivitis sicca Sense Organs 1.02 0.793 – 1.32 0.869 79 304 exclusion phecode
371 Inflammation of the eye Sense Organs 0.942 0.892 – 0.994 0.0289 1779 5798 exclusion phecode
371.1 Uveitis, noninfectious or NOS Sense Organs 0.912 0.788 – 1.06 0.217 210 1129 exclusion phecode
371.2 Conjunctivitis, noninfectious Sense Organs 0.923 0.826 – 1.03 0.158 355 1858 exclusion phecode
371.21 Allergic conjunctivitis Sense Organs 0.938 0.832 – 1.06 0.293 302 1566 exclusion phecode
371.3 Inflammation of eyelids Sense Organs 0.931 0.877 – 0.988 0.0192 1399 4897 exclusion phecode
371.33 Noninfectious dermatoses of eyelid Sense Organs 0.914 0.672 – 1.24 0.567 47 247 exclusion phecode
372 Disorders of conjunctiva Sense Organs 1.05 0.936 – 1.17 0.433 420 2128 exclusion phecode
374 Other disorders of eyelids Sense Organs 0.98 0.917 – 1.05 0.544 1102 4337 exclusion phecode
374.1 Ectropion or entropion Sense Organs 0.873 0.733 – 1.04 0.13 142 758 exclusion phecode
374.2 Lagophthalmos Sense Organs 0.888 0.653 – 1.21 0.45 46 369 exclusion phecode
374.3 Ptosis of eyelid Sense Organs 0.975 0.878 – 1.08 0.639 404 1973 exclusion phecode
374.6 Dermatochalasis Sense Organs 0.958 0.864 – 1.06 0.417 430 1859 exclusion phecode
375 Disorders of lacrimal system Sense Organs 0.936 0.882 – 0.994 0.0309 1517 4633 exclusion phecode
375.1 Dry eyes Sense Organs 0.958 0.904 – 1.01 0.143 1672 4750 exclusion phecode
375.2 Epiphora Sense Organs 0.908 0.766 – 1.08 0.269 167 816 exclusion phecode
376 Disorders of the orbit Sense Organs 0.943 0.738 – 1.21 0.639 77 591 exclusion phecode
377 Disorders of optic nerve and visual pathways Sense Organs 1.03 0.911 – 1.17 0.616 296 1648 exclusion phecode
377.1 Optic atrophy Sense Organs 0.973 0.8 – 1.18 0.785 123 616 exclusion phecode
377.3 Optic neuritis/neuropathy Sense Organs 1.07 0.914 – 1.25 0.396 174 1003 exclusion phecode
378
Strabismus and other disorders of binocular eye
Strabismus and other disorders of binocular eye movements
 Sense Organs 1 0.904 – 1.11 0.947 423 2264 exclusion phecode
378.1 Strabismus (not specified as paralytic) Sense Organs 0.952 0.84 – 1.08 0.434 289 1521 exclusion phecode
378.2 Nystagmus and other irregular eye movements Sense Organs 1.03 0.764 – 1.39 0.849 54 303 exclusion phecode
378.5 Paralytic strabismus Sense Organs 0.934 0.753 – 1.16 0.537 96 594 exclusion phecode
379 Other disorders of eye Sense Organs 0.961 0.912 – 1.01 0.133 2101 5291 exclusion phecode
379.1 Scleritis and episcleritis Sense Organs 0.998 0.76 – 1.31 0.991 66 348 exclusion phecode
379.2 Disorders of vitreous body Sense Organs 0.945 0.89 – 1 0.062 1562 4216 exclusion phecode
379.3 Aphakia and other disorders of lens Sense Organs 0.793 0.608 – 1.03 0.0871 65 299 exclusion phecode
379.4 Anomalies of pupillary function Sense Organs 0.843 0.69 – 1.03 0.0966 106 595 exclusion phecode
379.5 Disorders of iris and ciliary body Sense Organs 0.884 0.72 – 1.09 0.238 115 651 exclusion phecode
379.51 Pigmentary iris degeneration Sense Organs 1.04 0.63 – 1.73 0.867 22 111 exclusion phecode
379.9 Pain, swelling or discharge of eye Sense Organs 0.878 0.788 – 0.978 0.0181 404 1996 exclusion phecode
380 Disorders of external ear Sense Organs 0.989 0.922 – 1.06 0.752 981 4293 exclusion phecode
380.1 Otitis externa Sense Organs 0.972 0.889 – 1.06 0.527 578 3124 exclusion phecode
380.4 Impacted cerumen Sense Organs 1 0.938 – 1.07 0.999 1172 4895 exclusion phecode
381 Otitis media and Eustachian tube disorders Sense Organs 0.998 0.941 – 1.06 0.934 1408 6837 exclusion phecode
381.1 Otitis media Sense Organs 1.02 0.957 – 1.1 0.484 995 5630 exclusion phecode
381.11 Suppurative and unspecified otitis media Sense Organs 1.03 0.952 – 1.11 0.501 840 4876 exclusion phecode
381.2 Eustachian tube disorders Sense Organs 0.957 0.881 – 1.04 0.307 665 3656 exclusion phecode
381.3 Mastoiditis & related conditions Sense Organs 1.09 0.774 – 1.52 0.632 36 299 exclusion phecode
381.9 Otorrhea Sense Organs 0.99 0.796 – 1.23 0.931 92 686 exclusion phecode
382 Otalgia Sense Organs 1.01 0.932 – 1.1 0.751 668 3697 exclusion phecode
383 Otosclerosis Sense Organs 0.898 0.588 – 1.37 0.619 19 221 exclusion phecode
384 Other disorders of tympanic membrane Sense Organs 1.03 0.856 – 1.23 0.769 133 932 exclusion phecode
384.1 Myringitis Sense Organs 0.913 0.534 – 1.56 0.74 14 102 exclusion phecode
384.4 Perforation of tympanic membrane Sense Organs 1.05 0.848 – 1.3 0.661 99 727 exclusion phecode
385 Other disorders of middle ear and mastoid Sense Organs 1.26 1 – 1.59 0.0467 87 749 exclusion phecode
385.3 Cholesteatoma Sense Organs 1.49 1.07 – 2.08 0.0172 41 449 exclusion phecode
385.5
Tympanosclerosis and middle ear disease related
Tympanosclerosis and middle ear disease related to otitis media
 Sense Organs 0.847 0.561 – 1.28 0.431 25 208 exclusion phecode
386
Vertiginous syndromes and other disorders of
Vertiginous syndromes and other disorders of vestibular system
 Sense Organs 1.01 0.926 – 1.09 0.891 695 3334 exclusion phecode
386.1 Meniere's disease Sense Organs 1.14 0.912 – 1.43 0.249 93 608 exclusion phecode
386.2 Peripheral or central vertigo Sense Organs 1.02 0.938 – 1.12 0.589 603 2850 exclusion phecode
386.21 Central origin vertigo Sense Organs 1.06 0.959 – 1.18 0.248 453 2198 exclusion phecode
386.3 Labyrinthitis Sense Organs 1.04 0.951 – 1.15 0.365 540 2695 exclusion phecode
386.9
Dizziness and giddiness (Light-headedness and
Dizziness and giddiness (Light-headedness and vertigo)
 Sense Organs 1.03 0.982 – 1.08 0.241 2621 6767 exclusion phecode
388 Other disorders of ear Sense Organs 0.994 0.882 – 1.12 0.927 317 1867 exclusion phecode
389 Hearing loss Sense Organs 1.03 0.983 – 1.08 0.216 2596 6848 exclusion phecode
389.1 Sensorineural hearing loss Sense Organs 0.97 0.914 – 1.03 0.321 1458 5314 exclusion phecode
389.2 Conductive hearing loss Sense Organs 1.04 0.905 – 1.19 0.589 238 1661 exclusion phecode
389.3 Degenerative and vascular disorders of ear Sense Organs 0.744 0.59 – 0.94 0.0132 87 385 exclusion phecode
389.4 Tinnitus Sense Organs 0.98 0.906 – 1.06 0.603 755 4233 exclusion phecode
389.5 Disorders of acoustic nerve Sense Organs 1.07 0.757 – 1.51 0.703 38 203 exclusion phecode
394 Rheumatic disease of the heart valves Circulatory System 1.05 0.966 – 1.14 0.258 818 2497 exclusion phecode
394.1 Mitral valve stenosis and aortic valve stenosis Circulatory System 1.05 0.897 – 1.22 0.565 223 686 exclusion phecode
394.2 Mitral valve disease Circulatory System 1.01 0.877 – 1.16 0.886 253 833 exclusion phecode
394.3 Aortic valve disease Circulatory System 1.07 0.854 – 1.33 0.574 118 313 exclusion phecode
394.4 Acute rheumatic heart disease Circulatory System 0.551 0.339 – 0.898 0.0168 28 84 exclusion phecode
394.7 Disease of tricuspid valve Circulatory System 1.07 0.944 – 1.22 0.285 342 992 exclusion phecode
395 Heart valve disorders Circulatory System 1.13 1.07 – 1.19 2.26e-05 1781 5007 exclusion phecode
395.1 Nonrheumatic mitral valve disorders Circulatory System 1.11 1.03 – 1.19 0.00521 944 3695 exclusion phecode
395.2 Nonrheumatic aortic valve disorders Circulatory System 1.16 1.08 – 1.24 6.41e-05 1106 3153 exclusion phecode
395.3 Nonrheumatic tricuspid valve disorders Circulatory System 1.1 0.956 – 1.26 0.186 271 916 exclusion phecode
395.4 Nonrheumatic pulmonary valve disorders Circulatory System 1.04 0.733 – 1.47 0.832 49 220 exclusion phecode
395.6 Heart valve replaced Circulatory System 1.11 1.01 – 1.22 0.0253 632 1913 exclusion phecode
396 Abnormal heart sounds Circulatory System 1.1 1.04 – 1.16 0.000962 1701 6102 exclusion phecode
401 Hypertension Circulatory System 1.1 1.04 – 1.15 0.000323 6218 3441 exclusion phecode
401.1 Essential hypertension Circulatory System 1.09 1.04 – 1.15 0.00041 6184 3441 exclusion phecode
401.2 Hypertensive heart and/or renal disease Circulatory System 1.2 1.11 – 1.29 1.18e-06 1824 1963 exclusion phecode
401.21 Hypertensive heart disease Circulatory System 1.2 1.07 – 1.34 0.00174 503 865 exclusion phecode
401.22 Hypertensive chronic kidney disease Circulatory System 1.18 1.09 – 1.27 3.6e-05 1331 1724 exclusion phecode
401.3 Other hypertensive complications Circulatory System 1.19 1.11 – 1.28 3.82e-06 1319 2190 exclusion phecode
411 Ischemic Heart Disease Circulatory System 1.22 1.17 – 1.29 7.13e-16 3542 4571 exclusion phecode
411.1 Unstable angina (intermediate coronary syndrome) Circulatory System 1.29 1.17 – 1.43 6.67e-07 623 1458 exclusion phecode
411.2 Myocardial infarction Circulatory System 1.23 1.15 – 1.31 5.17e-10 1481 3181 exclusion phecode
411.3 Angina pectoris Circulatory System 1.25 1.17 – 1.34 1.01e-10 1377 2730 exclusion phecode
411.4 Coronary atherosclerosis Circulatory System 1.23 1.17 – 1.29 5.79e-15 3191 4127 exclusion phecode
411.41 Aneurysm and dissection of heart Circulatory System 1.46 1.11 – 1.93 0.00703 103 261 exclusion phecode
411.8
Other chronic ischemic heart disease
Other chronic ischemic heart disease, unspecified
 Circulatory System 1.24 1.18 – 1.31 2.88e-15 2730 3819 exclusion phecode
411.9
Other acute and subacute forms of ischemic
Other acute and subacute forms of ischemic heart disease
 Circulatory System 1.22 1.05 – 1.42 0.00849 270 766 exclusion phecode
414 Other forms of chronic heart disease Circulatory System 1.23 1.16 – 1.31 4.83e-11 1601 3367 exclusion phecode
414.2 ASCVD Circulatory System 1.14 1.01 – 1.28 0.03 428 1190 exclusion phecode
415 Pulmonary heart disease Circulatory System 1.07 1.01 – 1.14 0.0325 1283 5664 exclusion phecode
415.1 Acute pulmonary heart disease Circulatory System 1.05 0.966 – 1.15 0.242 598 3595 exclusion phecode
415.11 Pulmonary embolism and infarction, acute Circulatory System 1.05 0.966 – 1.15 0.235 594 3582 exclusion phecode
415.2 Chronic pulmonary heart disease Circulatory System 1.09 1.01 – 1.18 0.0219 884 3616 exclusion phecode
415.21 Primary pulmonary hypertension Circulatory System 1.09 0.966 – 1.23 0.163 370 1449 exclusion phecode
416 Cardiomegaly Circulatory System 0.96 0.879 – 1.05 0.365 635 2573 exclusion phecode
418 Nonspecific chest pain Circulatory System 1.03 0.993 – 1.08 0.104 4841 4792 exclusion phecode
418.1 Precordial pain Circulatory System 1.07 0.981 – 1.17 0.127 699 2093 exclusion phecode
420 Carditis Circulatory System 1.04 0.962 – 1.13 0.304 742 3111 exclusion phecode
420.1 Myocarditis Circulatory System 1.11 0.807 – 1.53 0.516 49 193 exclusion phecode
420.2 Pericarditis Circulatory System 0.996 0.89 – 1.11 0.939 376 1611 exclusion phecode
420.21 Acute pericarditis Circulatory System 0.985 0.767 – 1.26 0.904 86 315 exclusion phecode
420.22 Chronic pericarditis Circulatory System 1.09 0.79 – 1.5 0.604 61 205 exclusion phecode
420.3 Endocarditis Circulatory System 1 0.895 – 1.12 0.972 388 1542 exclusion phecode
425 Cardiomyopathy Circulatory System 1.13 1.05 – 1.21 0.000529 1064 3986 exclusion phecode
425.1 Primary/intrinsic cardiomyopathies Circulatory System 1.12 1.04 – 1.2 0.00177 1032 3842 exclusion phecode
425.11 Hypertrophic obstructive cardiomyopathy Circulatory System 0.999 0.798 – 1.25 0.993 103 429 exclusion phecode
425.12 Other hypertrophic cardiomyopathy Circulatory System 1.22 0.952 – 1.57 0.116 81 364 exclusion phecode
425.2 Secondary/extrinsic cardiomyopathies Circulatory System 1.04 0.873 – 1.23 0.69 166 675 exclusion phecode
425.8 Other cardiomyopathy Circulatory System 0.858 0.612 – 1.2 0.372 46 159 exclusion phecode
426 Cardiac conduction disorders Circulatory System 1.09 1.03 – 1.15 0.00142 4609 3177 exclusion phecode
426.2 Atrioventricular [AV] block Circulatory System 1.11 1.01 – 1.22 0.0268 947 1279 exclusion phecode
426.21 First degree AV block Circulatory System 1.1 0.993 – 1.23 0.0661 655 984 exclusion phecode
426.22 Mobitz II AV block Circulatory System 0.843 0.572 – 1.24 0.389 38 75 exclusion phecode
426.23 Second degree AV block Circulatory System 1.17 0.937 – 1.45 0.169 122 254 exclusion phecode
426.24 Atrioventricular block, complete Circulatory System 1.15 0.977 – 1.35 0.0932 265 449 exclusion phecode
426.25 Other heart block Circulatory System 1.01 0.775 – 1.32 0.923 108 214 exclusion phecode
426.3 Bundle branch block Circulatory System 1.11 1.02 – 1.21 0.0147 1025 1573 exclusion phecode
426.31 Right bundle branch block Circulatory System 1.09 0.983 – 1.2 0.104 615 1207 exclusion phecode
426.32 Left bundle branch block Circulatory System 1.06 0.95 – 1.19 0.284 483 945 exclusion phecode
426.4 Anomalous atrioventricular excitation Circulatory System 0.83 0.478 – 1.44 0.508 20 80 exclusion phecode
426.7 Abnormal electrocardiogram [ECG] [EKG] Circulatory System 1.09 1.04 – 1.15 0.00108 4182 3155 exclusion phecode
426.8 Other cardiac conduction disorders Circulatory System 1.07 0.937 – 1.21 0.33 334 857 exclusion phecode
426.9 Cardiac pacemaker/device in situ Circulatory System 1.16 1.05 – 1.27 0.00232 799 1301 exclusion phecode
426.91 Cardiac pacemaker in situ Circulatory System 1.13 1.01 – 1.26 0.0361 527 914 exclusion phecode
426.92 Cardiac defibrillator in situ Circulatory System 1.17 1.04 – 1.31 0.0103 468 847 exclusion phecode
427 Cardiac dysrhythmias Circulatory System 1.09 1.03 – 1.14 0.000817 5493 3254 exclusion phecode
427.1 Paroxysmal tachycardia, unspecified Circulatory System 1.14 1.06 – 1.24 0.000999 1058 2099 exclusion phecode
427.11 Paroxysmal supraventricular tachycardia Circulatory System 1.12 1.02 – 1.24 0.0206 601 1627 exclusion phecode
427.12 Paroxysmal ventricular tachycardia Circulatory System 1.18 1.07 – 1.31 0.00149 624 1182 exclusion phecode
427.2 Atrial fibrillation and flutter Circulatory System 1.13 1.05 – 1.21 0.000819 2013 2138 exclusion phecode
427.21 Atrial fibrillation Circulatory System 1.12 1.05 – 1.21 0.00127 1972 2090 exclusion phecode
427.22 Atrial flutter Circulatory System 1.09 0.99 – 1.2 0.0793 764 1206 exclusion phecode
427.3 Other specified cardiac dysrhythmias Circulatory System 1.1 1.04 – 1.16 0.000811 3224 3171 exclusion phecode
427.4 Cardiac arrest and ventricular fibrillation Circulatory System 1.11 0.957 – 1.28 0.169 270 627 exclusion phecode
427.41 Ventricular fibrillation and flutter Circulatory System 1.28 1.01 – 1.63 0.0421 125 292 exclusion phecode
427.42 Cardiac arrest Circulatory System 1.05 0.889 – 1.23 0.588 204 501 exclusion phecode
427.5 Arrhythmia (cardiac) NOS Circulatory System 1.1 1.03 – 1.16 0.00253 2442 3146 exclusion phecode
427.6 Premature beats Circulatory System 1.11 1.03 – 1.21 0.01 1033 1948 exclusion phecode
427.61 Supraventricular premature beats Circulatory System 1.1 0.956 – 1.27 0.183 309 774 exclusion phecode
427.7 Tachycardia NOS Circulatory System 1.1 1.03 – 1.17 0.00316 1836 3185 exclusion phecode
427.8 Sinoatrial node dysfunction (Bradycardia) Circulatory System 1.09 0.968 – 1.23 0.152 440 822 exclusion phecode
427.9 Palpitations Circulatory System 1.07 1 – 1.14 0.0411 1748 3146 exclusion phecode
428 Congestive heart failure; nonhypertensive Circulatory System 1.16 1.1 – 1.23 6.73e-07 2080 3117 exclusion phecode
428.1 Congestive heart failure (CHF) NOS Circulatory System 1.17 1.1 – 1.25 5.25e-07 1808 2929 exclusion phecode
428.2 Heart failure NOS Circulatory System 1.15 1.08 – 1.23 7.35e-06 1810 2822 exclusion phecode
428.3
Heart failure with reduced EF [Systolic or
Heart failure with reduced EF [Systolic or combined heart failure]
 Circulatory System 1.23 1.14 – 1.33 3.21e-07 1027 1937 exclusion phecode
428.4
Heart failure with preserved EF [Diastolic
Heart failure with preserved EF [Diastolic heart failure]
 Circulatory System 1.1 1.01 – 1.19 0.0277 932 1778 exclusion phecode
429
Ill-defined descriptions and complications of
Ill-defined descriptions and complications of heart disease
 Circulatory System 1.1 1.06 – 1.15 1.03e-05 4681 4529 exclusion phecode
429.1 Heart transplant/surgery Circulatory System 1.18 1.08 – 1.3 0.000473 669 1550 exclusion phecode
429.2 Abnormal function study of cardiovascular system Circulatory System 1.11 1.06 – 1.17 5.55e-05 2766 4064 exclusion phecode
429.3 Symptoms involving cardiovascular system Circulatory System 1.11 1.06 – 1.16 1.93e-05 3645 4527 exclusion phecode
429.9 Cardiac complications, not elsewhere classified Circulatory System 1.15 1.02 – 1.31 0.0227 348 884 exclusion phecode
430 Intracranial hemorrhage Circulatory System 1.1 0.959 – 1.25 0.178 262 1573 exclusion phecode
430.1 Subarachnoid hemorrhage Circulatory System 1.16 0.914 – 1.47 0.222 89 477 exclusion phecode
430.2 Intracerebral hemorrhage Circulatory System 1.11 0.906 – 1.36 0.319 116 661 exclusion phecode
430.3 Subdural hemorrhage Circulatory System 1.07 0.869 – 1.32 0.521 102 568 exclusion phecode
433 Cerebrovascular disease Circulatory System 1.11 1.05 – 1.17 0.000153 1974 5967 exclusion phecode
433.1 Occlusion and stenosis of precerebral arteries Circulatory System 1.1 1.02 – 1.18 0.019 907 3195 exclusion phecode
433.11
Occlusion of cerebral arteries, with cerebral
Occlusion of cerebral arteries, with cerebral infarction
 Circulatory System 1.14 0.938 – 1.37 0.193 132 551 exclusion phecode
433.12 Cerebral atherosclerosis Circulatory System 1.19 0.822 – 1.72 0.36 49 181 exclusion phecode
433.2 Occlusion of cerebral arteries Circulatory System 1.11 1.04 – 1.2 0.00354 895 4145 exclusion phecode
433.21
Cerebral artery occlusion, with cerebral
Cerebral artery occlusion, with cerebral infarction
 Circulatory System 1.11 1.03 – 1.2 0.00441 868 4020 exclusion phecode
433.3 Cerebral ischemia Circulatory System 1.08 1.01 – 1.16 0.0244 1077 4352 exclusion phecode
433.31 Transient cerebral ischemia Circulatory System 1.06 0.988 – 1.14 0.101 944 3957 exclusion phecode
433.5 Cerebral aneurysm Circulatory System 1.1 0.9 – 1.34 0.35 110 788 exclusion phecode
433.6 Acute, but ill-defined cerebrovascular disease Circulatory System 1.02 0.884 – 1.17 0.831 283 1004 exclusion phecode
433.8 Late effects of cerebrovascular disease Circulatory System 1.09 0.962 – 1.24 0.176 321 1355 exclusion phecode
440 Atherosclerosis Circulatory System 1.1 1.03 – 1.18 0.0029 1322 3265 exclusion phecode
440.1 Atherosclerosis of renal artery Circulatory System 1.22 0.986 – 1.52 0.0669 118 343 exclusion phecode
440.2 Atherosclerosis of the extremities Circulatory System 1.07 0.994 – 1.16 0.0719 866 2432 exclusion phecode
440.21
Atherosclerosis of native arteries of the
Atherosclerosis of native arteries of the extremities with ulceration or gangrene
 Circulatory System 1.22 1.03 – 1.45 0.0192 184 651 exclusion phecode
440.22
Atherosclerosis of native arteries of the
Atherosclerosis of native arteries of the extremities with intermittent claudication
 Circulatory System 1.06 0.968 – 1.16 0.207 627 1828 exclusion phecode
440.9 Atherosclerosis of aorta Circulatory System 1.17 1.05 – 1.3 0.00468 475 1362 exclusion phecode
441 Vascular insufficiency of intestine Circulatory System 0.945 0.812 – 1.1 0.459 231 883 exclusion phecode
441.1 Acute vascular insufficiency of intestine Circulatory System 0.908 0.734 – 1.12 0.372 112 418 exclusion phecode
441.2 Chronic vascular insufficiency of intestine Circulatory System 0.961 0.729 – 1.27 0.781 64 277 exclusion phecode
442 Other aneurysm Circulatory System 1.09 1.02 – 1.17 0.0131 1158 3401 exclusion phecode
442.1 Aortic aneurysm Circulatory System 1.09 1.01 – 1.17 0.0269 940 2672 exclusion phecode
442.11 Abdominal aortic aneurysm Circulatory System 1.16 1.05 – 1.28 0.00424 509 1708 exclusion phecode
442.2 Aneurysm of iliac artery Circulatory System 1.2 0.94 – 1.52 0.145 90 304 exclusion phecode
442.3 Aneurysm of artery of lower extremity Circulatory System 1.32 1.01 – 1.71 0.0425 83 266 exclusion phecode
442.4 Arterial dissection Circulatory System 0.971 0.764 – 1.24 0.813 85 271 exclusion phecode
442.8 Aneurysm of other specified artery Circulatory System 1.22 1.02 – 1.47 0.0334 148 621 exclusion phecode
443 Peripheral vascular disease Circulatory System 1.13 1.07 – 1.21 8.08e-05 1382 4093 exclusion phecode
443.1 Raynaud's syndrome Circulatory System 1.07 0.93 – 1.23 0.351 240 1213 exclusion phecode
443.7
Peripheral angiopathy in diseases classified
Peripheral angiopathy in diseases classified elsewhere
 Circulatory System 1.11 0.932 – 1.32 0.244 170 626 exclusion phecode
443.8 Other specified peripheral vascular diseases Circulatory System 1.13 1.05 – 1.21 0.000586 1118 3679 exclusion phecode
443.9 Peripheral vascular disease, unspecified Circulatory System 1.14 1.06 – 1.22 0.000292 1136 3199 exclusion phecode
444 Arterial embolism and thrombosis Circulatory System 1.12 1 – 1.26 0.049 390 1423 exclusion phecode
444.1
Arterial embolism and thrombosis of lower
Arterial embolism and thrombosis of lower extremity artery
 Circulatory System 1.11 0.933 – 1.33 0.235 162 568 exclusion phecode
444.2 Embolism and thrombosis of abdominal aorta Circulatory System 1.31 0.986 – 1.74 0.0622 76 244 exclusion phecode
446 Polyarteritis nodosa and allied conditions Circulatory System 1.11 0.949 – 1.31 0.187 185 819 exclusion phecode
446.4 Wegener's granulomatosis Circulatory System 1.49 1.04 – 2.13 0.0302 39 193 exclusion phecode
446.5 Giant cell arteritis Circulatory System 1.11 0.743 – 1.65 0.62 33 117 exclusion phecode
446.9 Arteritis NOS Circulatory System 1.06 0.863 – 1.3 0.59 119 542 exclusion phecode
447 Other disorders of arteries and arterioles Circulatory System 1.09 1.02 – 1.16 0.0146 1220 3675 exclusion phecode
447.1 Stricture of artery Circulatory System 1.13 0.98 – 1.31 0.0917 255 828 exclusion phecode
447.7 Aortic ectasia Circulatory System 1.01 0.903 – 1.12 0.916 432 1374 exclusion phecode
448 Disease of capillaries Circulatory System 0.967 0.871 – 1.07 0.525 423 2114 exclusion phecode
450 Noninfectious disorders of lymphatic channels Circulatory System 0.955 0.873 – 1.04 0.316 544 4198 exclusion phecode
451 Phlebitis and thrombophlebitis Circulatory System 1.01 0.884 – 1.15 0.884 271 1178 exclusion phecode
451.2
Phlebitis and thrombophlebitis of lower
Phlebitis and thrombophlebitis of lower extremities
 Circulatory System 0.945 0.754 – 1.19 0.625 88 407 exclusion phecode
452 Other venous embolism and thrombosis Circulatory System 1 0.946 – 1.07 0.885 1474 4441 exclusion phecode
452.1 Iatrogenic pulmonary embolism and infarction Circulatory System 1.01 0.792 – 1.28 0.967 100 433 exclusion phecode
452.2 Deep vein thrombosis [DVT] Circulatory System 1 0.935 – 1.08 0.892 937 3985 exclusion phecode
452.8 Postphlebitic syndrome Circulatory System 0.72 0.524 – 0.989 0.0427 32 224 exclusion phecode
453 Chronic venous hypertension Circulatory System 0.936 0.757 – 1.16 0.543 97 374 exclusion phecode
454 Varicose veins Circulatory System 0.915 0.852 – 0.983 0.015 973 3757 exclusion phecode
454.1 Varicose veins of lower extremity Circulatory System 0.92 0.854 – 0.992 0.0293 876 3296 exclusion phecode
454.11 Varicose veins of lower extremity, symptomtic Circulatory System 0.899 0.822 – 0.983 0.019 615 2370 exclusion phecode
455 Hemorrhoids Circulatory System 1.05 0.992 – 1.1 0.0965 2201 4612 exclusion phecode
456 Chronic venous insufficiency [CVI] Circulatory System 0.931 0.873 – 0.993 0.0291 1277 3892 exclusion phecode
457
Encounter for long-term (current) use of
Encounter for long-term (current) use of anticoagulants, antithrombotics, aspirin
 Circulatory System 1.13 1.04 – 1.23 0.00345 852 2324 exclusion phecode
457.2
Encounter for long-term (current) use of
Encounter for long-term (current) use of antiplatelets/antithrombotics
 Circulatory System 1.16 0.963 – 1.4 0.118 150 506 exclusion phecode
457.3 Encounter for long-term (current) use of aspirin Circulatory System 1.12 1.03 – 1.22 0.00834 802 2236 exclusion phecode
458 Hypotension Circulatory System 1.1 1.04 – 1.16 0.000625 2116 5153 exclusion phecode
458.1 Orthostatic hypotension Circulatory System 1.01 0.925 – 1.11 0.767 625 2289 exclusion phecode
458.2 Iatrogenic hypotension Circulatory System 1.09 0.983 – 1.21 0.103 494 1817 exclusion phecode
458.9 Hypotension NOS Circulatory System 1.1 1.04 – 1.16 0.000573 1940 4994 exclusion phecode
459 Other disorders of circulatory system Circulatory System 1.07 1.02 – 1.13 0.00362 2737 5607 exclusion phecode
459.1 Hemorrhage NOS Circulatory System 1.08 0.955 – 1.22 0.218 347 1451 exclusion phecode
459.7 Blood vessel replaced Circulatory System 1.12 1.01 – 1.24 0.0247 509 1952 exclusion phecode
459.9 Circulatory disease NEC Circulatory System 1.08 1.02 – 1.13 0.00482 2368 5371 exclusion phecode
464 Acute sinusitis Respiratory 0.939 0.89 – 0.99 0.0199 1924 4830 exclusion phecode
465
Acute upper respiratory infections of multiple
Acute upper respiratory infections of multiple or unspecified sites
 Respiratory 0.936 0.897 – 0.977 0.00241 3814 5406 exclusion phecode
465.2 Acute pharyngitis Respiratory 0.951 0.901 – 1 0.0629 2053 4764 exclusion phecode
465.4 Acute laryngitis and tracheitis Respiratory 0.962 0.804 – 1.15 0.672 147 702 exclusion phecode
470 Septal Deviations/Turbinate Hypertrophy Respiratory 0.915 0.829 – 1.01 0.0731 484 2635 exclusion phecode
471 Nasal polyps Respiratory 0.994 0.841 – 1.18 0.945 151 981 exclusion phecode
472 Chronic pharyngitis and nasopharyngitis Respiratory 0.933 0.858 – 1.02 0.111 689 2867 exclusion phecode
473 Diseases of the larynx and vocal cords Respiratory 0.904 0.837 – 0.976 0.00965 805 3933 exclusion phecode
473.1 Chronic laryngitis Respiratory 0.734 0.495 – 1.09 0.125 27 120 exclusion phecode
473.3 Paralysis/spasm of vocal cords or larynx Respiratory 0.993 0.84 – 1.17 0.938 157 952 exclusion phecode
473.4 Voice disturbance Respiratory 0.954 0.875 – 1.04 0.286 627 3351 exclusion phecode
474 Acute and chronic tonsillitis Respiratory 0.914 0.801 – 1.04 0.179 283 1201 exclusion phecode
474.1 Acute tonsillitis Respiratory 0.997 0.801 – 1.24 0.977 104 451 exclusion phecode
474.2 Chronic tonsillitis and adenoiditis Respiratory 0.9 0.775 – 1.05 0.168 214 939 exclusion phecode
475 Chronic sinusitis Respiratory 0.936 0.881 – 0.994 0.03 1476 4360 exclusion phecode
475.9 Postnasal drip Respiratory 0.923 0.822 – 1.04 0.178 379 1632 exclusion phecode
476 Allergic rhinitis Respiratory 0.923 0.883 – 0.966 0.000466 3676 4423 exclusion phecode
477 Epistaxis or throat hemorrhage Respiratory 1.06 0.956 – 1.17 0.269 490 1877 exclusion phecode
478 Throat pain Respiratory 0.94 0.769 – 1.15 0.549 127 646 exclusion phecode
479 Other upper respiratory disease Respiratory 0.944 0.893 – 0.997 0.0398 1850 4404 exclusion phecode
480 Pneumonia Respiratory 1.03 0.978 – 1.08 0.279 2144 6201 exclusion phecode
480.1 Bacterial pneumonia Respiratory 1.07 0.967 – 1.18 0.195 515 2103 exclusion phecode
480.11 Pneumococcal pneumonia Respiratory 1.09 0.945 – 1.26 0.238 254 1037 exclusion phecode
480.12 Pseudomonal pneumonia Respiratory 1.16 0.877 – 1.54 0.294 76 254 exclusion phecode
480.13 MRSA pneumonia Respiratory 0.908 0.666 – 1.24 0.539 53 240 exclusion phecode
480.2 Viral pneumonia Respiratory 1.01 0.824 – 1.24 0.909 110 448 exclusion phecode
480.3 Pneumonia due to fungus (mycoses) Respiratory 1.23 0.926 – 1.62 0.154 71 309 exclusion phecode
480.5 Bronchopneumonia and lung abscess Respiratory 0.869 0.646 – 1.17 0.351 55 239 exclusion phecode
481 Influenza Respiratory 0.971 0.888 – 1.06 0.519 591 2674 exclusion phecode
483 Acute bronchitis and bronchiolitis Respiratory 0.963 0.909 – 1.02 0.208 1461 5219 exclusion phecode
495 Asthma Respiratory 1 0.957 – 1.06 0.844 2235 6145 exclusion phecode
495.1 Chronic obstructive asthma Respiratory 1.07 0.892 – 1.27 0.482 153 787 exclusion phecode
495.11 Chronic obstructive asthma with exacerbation Respiratory 1.3 0.907 – 1.86 0.154 48 206 exclusion phecode
495.2 Asthma with exacerbation Respiratory 0.979 0.895 – 1.07 0.634 573 3051 exclusion phecode
496 Chronic airway obstruction Respiratory 1.04 0.983 – 1.11 0.165 1459 5192 exclusion phecode
496.1 Emphysema Respiratory 1.04 0.953 – 1.13 0.387 612 3619 exclusion phecode
496.2 Chronic bronchitis Respiratory 1.06 0.992 – 1.13 0.0856 1144 4873 exclusion phecode
496.21 Obstructive chronic bronchitis Respiratory 1.08 1 – 1.15 0.0359 1045 4667 exclusion phecode
496.3 Bronchiectasis Respiratory 1.15 0.985 – 1.34 0.078 208 1154 exclusion phecode
497 Bronchitis Respiratory 1.04 0.958 – 1.12 0.382 792 3795 exclusion phecode
498 Acute bronchospasm Respiratory 1.01 0.871 – 1.18 0.86 220 953 exclusion phecode
499 Cystic fibrosis Respiratory 1.01 0.757 – 1.36 0.927 67 376 exclusion phecode
500 Lung disease due to external agents Respiratory 0.912 0.782 – 1.06 0.24 197 955 exclusion phecode
500.1 Extrinsic allergic alveolitis Respiratory 0.958 0.678 – 1.35 0.807 35 150 exclusion phecode
500.2 Pneumoconiosis Respiratory 0.982 0.701 – 1.38 0.915 35 153 exclusion phecode
501 Pneumonitis due to inhalation of food or vomitus Respiratory 1.08 0.937 – 1.26 0.278 235 1136 exclusion phecode
502 Postinflammatory pulmonary fibrosis Respiratory 0.977 0.863 – 1.11 0.718 308 1442 exclusion phecode
503 Pulmonary congestion and hypostasis Respiratory 1.1 0.986 – 1.23 0.0874 448 1624 exclusion phecode
504 Other alveolar and parietoalveolar pneumonopathy Respiratory 0.985 0.853 – 1.14 0.834 228 1095 exclusion phecode
504.1 Idiopathic fibrosing alveolitis Respiratory 1.02 0.839 – 1.24 0.853 122 579 exclusion phecode
505 Other pulmonary inflamation or edema Respiratory 1.09 1.01 – 1.18 0.0262 834 2901 exclusion phecode
506 Empyema and pneumothorax Respiratory 1.11 1.03 – 1.19 0.00387 1066 4202 exclusion phecode
507 Pleurisy; pleural effusion Respiratory 1.06 0.993 – 1.13 0.0806 1152 4433 exclusion phecode
508
Pulmonary collapse; interstitial and
Pulmonary collapse; interstitial and compensatory emphysema
 Respiratory 1.06 0.986 – 1.15 0.111 870 3907 exclusion phecode
509 Respiratory failure, insufficiency, arrest Respiratory 1.15 1.09 – 1.22 9.83e-07 1677 4953 exclusion phecode
509.1 Respiratory failure Respiratory 1.09 1.01 – 1.18 0.0367 802 3328 exclusion phecode
509.2 Respiratory insufficiency Respiratory 1.16 1.05 – 1.28 0.00385 513 2058 exclusion phecode
509.3
Pulmonary insufficiency or respiratory failure
Pulmonary insufficiency or respiratory failure following trauma and surgery
 Respiratory 1.11 1.03 – 1.21 0.00928 789 2829 exclusion phecode
509.8
Dependence on respirator [Ventilator] or
Dependence on respirator [Ventilator] or supplemental oxygen
 Respiratory 1.18 1.08 – 1.28 0.000149 717 2991 exclusion phecode
510 Other diseases of lung Respiratory 1.01 0.957 – 1.06 0.809 2036 6644 exclusion phecode
510.2 Lung transplant Respiratory 1.07 0.852 – 1.34 0.565 104 352 exclusion phecode
512 Other symptoms of respiratory system Respiratory 1 0.961 – 1.05 0.851 6300 3373 exclusion phecode
512.1 Wheezing Respiratory 0.972 0.882 – 1.07 0.562 613 1758 exclusion phecode
512.2 Painful respiration Respiratory 1.02 0.947 – 1.11 0.555 942 2631 exclusion phecode
512.3 Abnormal chest sounds Respiratory 0.97 0.788 – 1.19 0.77 153 363 exclusion phecode
512.7 Shortness of breath Respiratory 1.04 0.987 – 1.09 0.15 3896 3353 exclusion phecode
512.8 Cough Respiratory 0.976 0.929 – 1.02 0.318 3808 3372 exclusion phecode
512.9 Other dyspnea Respiratory 1.02 0.969 – 1.07 0.496 3994 3364 exclusion phecode
513 Respiratory abnormalities Respiratory 1.03 0.989 – 1.08 0.144 4577 5094 exclusion phecode
513.3 Hypoventilation Respiratory 0.938 0.836 – 1.05 0.276 398 1491 exclusion phecode
513.31 Apnea Respiratory 1.02 0.863 – 1.2 0.841 189 786 exclusion phecode
513.32 Orthopnea Respiratory 0.898 0.72 – 1.12 0.34 123 364 exclusion phecode
513.4 Hyperventilation Respiratory 1.14 0.984 – 1.33 0.0808 239 743 exclusion phecode
513.8 Disorders of diaphragm Respiratory 1.13 0.897 – 1.44 0.292 95 411 exclusion phecode
514 Abnormal findings examination of lungs Respiratory 0.992 0.939 – 1.05 0.778 1588 6667 exclusion phecode
514.1
Abnormal results of function study of pulmonary
Abnormal results of function study of pulmonary system
 Respiratory 0.966 0.793 – 1.18 0.729 120 582 exclusion phecode
514.2 Solitary pulmonary nodule Respiratory 0.986 0.917 – 1.06 0.697 865 5271 exclusion phecode
516 Abnormal sputum Respiratory 1.07 0.942 – 1.22 0.298 281 1611 exclusion phecode
516.1 Hemoptysis Respiratory 1.12 0.971 – 1.28 0.122 232 1327 exclusion phecode
519
Other diseases of respiratory system, not
Other diseases of respiratory system, not elsewhere classified
 Respiratory 1.06 1.01 – 1.11 0.0283 2249 7145 exclusion phecode
519.1 Tracheostomy complications Respiratory 1.18 0.879 – 1.58 0.274 48 355 exclusion phecode
519.2 Respiratory complications Respiratory 1.05 0.888 – 1.23 0.59 169 773 exclusion phecode
519.8 Other diseases of respiratory system, NEC Respiratory 1.02 0.925 – 1.12 0.728 512 3067 exclusion phecode
519.9
Symptoms involving respiratory system and other
Symptoms involving respiratory system and other chest symptoms
 Respiratory 1.07 1.01 – 1.13 0.0149 1721 6322 exclusion phecode
520 Disorders of tooth development Digestive 0.815 0.628 – 1.06 0.124 56 672 exclusion phecode
520.1 Hereditary disturbances in tooth structure Digestive 0.834 0.583 – 1.19 0.321 29 331 exclusion phecode
520.2 Disturbances in tooth eruption Digestive 0.764 0.504 – 1.16 0.203 24 356 exclusion phecode
521 Diseases of hard tissues of teeth Digestive 1.03 0.9 – 1.19 0.632 223 1741 exclusion phecode
521.1 Dental caries Digestive 1.01 0.875 – 1.17 0.865 202 1618 exclusion phecode
521.2 Dental abrasion, erosion and attrition Digestive 1.31 0.74 – 2.34 0.351 17 83 exclusion phecode
522 Diseases of pulp and periapical tissues Digestive 1.1 0.934 – 1.29 0.258 179 1104 exclusion phecode
522.5 Periapical abscess Digestive 1.06 0.894 – 1.25 0.524 166 935 exclusion phecode
523 Gingival and periodontal diseases Digestive 0.952 0.826 – 1.1 0.499 207 1410 exclusion phecode
523.1 Gingivitis Digestive 0.708 0.523 – 0.958 0.0252 49 272 exclusion phecode
523.3 Periodontitis (acute or chronic) Digestive 0.961 0.798 – 1.16 0.681 109 710 exclusion phecode
523.31 Acute periodontitis Digestive 0.92 0.744 – 1.14 0.442 88 595 exclusion phecode
523.32 Chronic periodontitis Digestive 1.07 0.75 – 1.54 0.696 32 233 exclusion phecode
524 Dentofacial anomalies, including malocclusion Digestive 0.728 0.517 – 1.02 0.068 40 566 exclusion phecode
524.3 Anomalies of tooth position/malocclusion Digestive 0.669 0.422 – 1.06 0.089 21 325 exclusion phecode
525
Other diseases of the teeth and supporting
Other diseases of the teeth and supporting structures
 Digestive 0.999 0.878 – 1.14 0.993 265 1970 exclusion phecode
525.1 Loss of teeth or edentulism Digestive 1.05 0.823 – 1.34 0.696 72 683 exclusion phecode
526 Diseases of the jaws Digestive 0.939 0.864 – 1.02 0.138 627 4938 exclusion phecode
526.1 Cysts of the jaws Digestive 0.744 0.515 – 1.08 0.116 33 418 exclusion phecode
526.3 Anomalies of jaw size/symmetry Digestive 0.867 0.584 – 1.29 0.479 27 341 exclusion phecode
526.4 Temporomandibular joint disorders Digestive 0.969 0.87 – 1.08 0.563 385 2778 exclusion phecode
526.41 Temporomandibular joint disorder, unspecified Digestive 0.93 0.823 – 1.05 0.248 291 2172 exclusion phecode
526.42 Arthralgia/ankylosis of temporomandibular joint Digestive 0.936 0.793 – 1.11 0.437 157 1339 exclusion phecode
526.5 Inflammatory conditions of jaw Digestive 0.813 0.591 – 1.12 0.201 39 539 exclusion phecode
526.8 Exostosis of jaw Digestive 0.97 0.495 – 1.9 0.929 10 102 exclusion phecode
526.9 Jaw disease NOS Digestive 0.803 0.644 – 1 0.0519 82 944 exclusion phecode
527 Diseases of the salivary glands Digestive 1.03 0.932 – 1.13 0.597 472 3605 exclusion phecode
527.1 Hypertrophy of salivary gland Digestive 1.05 0.622 – 1.76 0.862 17 128 exclusion phecode
527.2 Sialoadenitis Digestive 1.09 0.898 – 1.33 0.379 114 782 exclusion phecode
527.7 Disturbance of salivary secretion Digestive 1.03 0.909 – 1.17 0.624 268 1945 exclusion phecode
527.8 Other specified diseases of the salivary glands Digestive 1.02 0.784 – 1.32 0.894 59 494 exclusion phecode
528
Diseases of the oral soft tissues, excluding
Diseases of the oral soft tissues, excluding lesions specific for gingiva and tongue
 Digestive 0.971 0.897 – 1.05 0.466 698 5234 exclusion phecode
528.1 Stomatitis and mucositis Digestive 0.81 0.703 – 0.934 0.00383 215 1333 exclusion phecode
528.11 Stomatitis and mucositis (ulcerative) Digestive 0.757 0.593 – 0.967 0.0255 67 401 exclusion phecode
528.12 Oral aphthae Digestive 0.829 0.66 – 1.04 0.108 89 479 exclusion phecode
528.3 Cellulitis and abscess of oral soft tissues Digestive 0.952 0.709 – 1.28 0.741 47 425 exclusion phecode
528.4 Cysts of oral soft tissues Digestive 1.2 0.772 – 1.87 0.414 22 225 exclusion phecode
528.41 Cyst of the salivary gland Digestive 0.938 0.564 – 1.56 0.804 16 139 exclusion phecode
528.5 Diseases of lips Digestive 0.923 0.77 – 1.11 0.386 148 966 exclusion phecode
528.6 Leukoplakia of oral mucosa Digestive 1.02 0.697 – 1.5 0.913 24 277 exclusion phecode
528.7 Sialolithiasis Digestive 1.52 1.12 – 2.05 0.00716 47 301 exclusion phecode
529 Diseases and other conditions of the tongue Digestive 1.01 0.867 – 1.18 0.901 182 1436 exclusion phecode
529.1 Glossitis Digestive 0.997 0.732 – 1.36 0.987 42 245 exclusion phecode
529.6 Glossodynia Digestive 0.952 0.686 – 1.32 0.769 43 360 exclusion phecode
530 Diseases of esophagus Digestive 0.988 0.947 – 1.03 0.563 4685 4629 exclusion phecode
530.1 Esophagitis, GERD and related diseases Digestive 0.988 0.947 – 1.03 0.585 4584 4629 exclusion phecode
530.11 GERD Digestive 0.985 0.944 – 1.03 0.486 4466 4628 exclusion phecode
530.12 Ulcer of esophagus Digestive 0.889 0.739 – 1.07 0.214 155 702 exclusion phecode
530.13 Barrett's esophagus Digestive 0.926 0.803 – 1.07 0.293 214 1320 exclusion phecode
530.14 Reflux esophagitis Digestive 0.922 0.85 – 0.999 0.0467 747 3050 exclusion phecode
530.15 Eosinophilic esophagitis Digestive 0.728 0.551 – 0.962 0.0255 66 369 exclusion phecode
530.2 Esophageal bleeding (varices/hemorrhage) Digestive 0.98 0.852 – 1.13 0.776 247 1130 exclusion phecode
530.3 Stricture and stenosis of esophagus Digestive 0.928 0.812 – 1.06 0.274 257 1468 exclusion phecode
530.5 Disorders of esophageal motility Digestive 0.995 0.838 – 1.18 0.958 161 916 exclusion phecode
530.6 Diverticulum of esophagus, acquired Digestive 1.42 0.834 – 2.42 0.197 16 208 exclusion phecode
530.7 Gastroesophageal laceration-hemorrhage syndrome Digestive 0.706 0.501 – 0.997 0.0481 39 157 exclusion phecode
530.9 Heartburn Digestive 0.936 0.851 – 1.03 0.176 520 2574 exclusion phecode
531 Peptic ulcer (excl. esophageal) Digestive 1.01 0.935 – 1.09 0.785 756 4293 exclusion phecode
531.1 Hemorrhage from gastrointestinal ulcer Digestive 0.978 0.835 – 1.14 0.78 172 806 exclusion phecode
531.2 Gastric ulcer Digestive 1.02 0.921 – 1.13 0.688 439 2531 exclusion phecode
531.3 Duodenal ulcer Digestive 0.994 0.852 – 1.16 0.943 191 978 exclusion phecode
531.4 Peptic ulcer, site unspecified Digestive 0.942 0.836 – 1.06 0.333 316 1750 exclusion phecode
531.5 Gastrojejunal ulcer Digestive 1.2 0.908 – 1.59 0.2 59 279 exclusion phecode
532 Dysphagia Digestive 0.984 0.928 – 1.04 0.598 1608 4368 exclusion phecode
535 Gastritis and duodenitis Digestive 0.997 0.932 – 1.07 0.929 1061 5159 exclusion phecode
535.1 Acute gastritis Digestive 1.01 0.912 – 1.13 0.789 420 2326 exclusion phecode
535.2 Atrophic gastritis Digestive 0.964 0.786 – 1.18 0.729 118 616 exclusion phecode
535.6 Duodenitis Digestive 1.02 0.848 – 1.23 0.814 138 663 exclusion phecode
535.8 Other specified gastritis Digestive 0.869 0.758 – 0.996 0.0436 261 1292 exclusion phecode
535.9 Gastritis and duodenitis, NOS Digestive 0.952 0.865 – 1.05 0.32 500 2461 exclusion phecode
536 Disorders of function of stomach Digestive 0.989 0.926 – 1.06 0.748 1084 5166 exclusion phecode
536.3 Gastroparesis Digestive 1.21 1.07 – 1.38 0.00282 303 1647 exclusion phecode
536.7
Complications of gastrostomy, colostomy and
Complications of gastrostomy, colostomy and enterostomy
 Digestive 1.04 0.851 – 1.28 0.683 108 637 exclusion phecode
536.8
Dyspepsia and other specified disorders of
Dyspepsia and other specified disorders of function of stomach
 Digestive 0.933 0.865 – 1.01 0.0733 823 4075 exclusion phecode
537 Other disorders of stomach and duodenum Digestive 1.09 1.03 – 1.16 0.00552 1292 5626 exclusion phecode
537.1 Lesions of stomach and duodenum Digestive 0.963 0.767 – 1.21 0.749 94 379 exclusion phecode
539 Bariatric surgery Digestive 0.933 0.853 – 1.02 0.129 574 2926 exclusion phecode
540 Appendiceal conditions Digestive 1.03 0.869 – 1.21 0.754 176 1004 exclusion phecode
540.1 Appendicitis Digestive 1.06 0.886 – 1.26 0.533 153 853 exclusion phecode
540.11 Acute appendicitis Digestive 1.02 0.839 – 1.24 0.856 126 718 exclusion phecode
550 Abdominal hernia Digestive 0.961 0.914 – 1.01 0.117 2113 7060 exclusion phecode
550.1 Inguinal hernia Digestive 0.885 0.81 – 0.967 0.00676 600 3158 exclusion phecode
550.2 Diaphragmatic hernia Digestive 0.954 0.887 – 1.03 0.205 844 4953 exclusion phecode
550.3 Femoral hernia Digestive 0.767 0.555 – 1.06 0.108 43 246 exclusion phecode
550.4 Umbilical hernia Digestive 0.956 0.864 – 1.06 0.382 473 2487 exclusion phecode
550.5 Ventral hernia Digestive 1.03 0.949 – 1.11 0.514 737 4045 exclusion phecode
550.6 Incisional hernia Digestive 1.04 0.942 – 1.16 0.412 414 2424 exclusion phecode
555
Inflammatory bowel disease and other
Inflammatory bowel disease and other gastroenteritis and colitis
 Digestive 1.06 0.952 – 1.18 0.289 411 2189 exclusion phecode
555.1 Regional enteritis Digestive 1.09 0.944 – 1.26 0.244 245 1242 exclusion phecode
555.2 Ulcerative colitis Digestive 1.05 0.914 – 1.2 0.504 264 1362 exclusion phecode
555.21 Ulcerative colitis (chronic) Digestive 1.03 0.866 – 1.22 0.746 171 765 exclusion phecode
556 Ulceration of the lower GI tract Digestive 0.933 0.81 – 1.08 0.343 274 1013 exclusion phecode
556.1 Ulceration of intestine Digestive 0.949 0.814 – 1.11 0.506 238 856 exclusion phecode
556.11
Angiodysplasia of intestine (without mention of
Angiodysplasia of intestine (without mention of hemorrhage)
 Digestive 0.933 0.744 – 1.17 0.547 109 397 exclusion phecode
557 Intestinal malabsorption (non-celiac) Digestive 0.889 0.817 – 0.968 0.00648 704 2540 exclusion phecode
557.1 Celiac disease Digestive 0.897 0.743 – 1.08 0.256 143 697 exclusion phecode
558 Noninfectious gastroenteritis Digestive 0.992 0.928 – 1.06 0.816 1195 3873 exclusion phecode
559 Ileostomy status Digestive 1.13 0.981 – 1.31 0.0899 233 1200 exclusion phecode
560 Intestinal obstruction without mention of hernia Digestive 0.969 0.901 – 1.04 0.409 952 3476 exclusion phecode
560.1 Paralytic ileus Digestive 1.01 0.916 – 1.12 0.809 492 2136 exclusion phecode
560.2 Impaction of intestine Digestive 0.812 0.671 – 0.983 0.0324 147 612 exclusion phecode
560.3 Peritoneal or intestinal adhesions Digestive 0.999 0.798 – 1.25 0.991 97 365 exclusion phecode
560.4 Other intestinal obstruction Digestive 0.963 0.877 – 1.06 0.433 559 2229 exclusion phecode
561 Symptoms involving digestive system Digestive 0.922 0.854 – 0.995 0.0364 876 3234 exclusion phecode
562 Diverticulosis and diverticulitis Digestive 0.91 0.86 – 0.963 0.000988 2298 3398 exclusion phecode
562.1 Diverticulosis Digestive 0.913 0.863 – 0.965 0.00144 2280 3388 exclusion phecode
562.2 Diverticulitis Digestive 0.89 0.806 – 0.982 0.0199 517 2200 exclusion phecode
564 Functional digestive disorders Digestive 0.978 0.934 – 1.02 0.355 3517 4203 exclusion phecode
564.1 Irritable Bowel Syndrome Digestive 0.969 0.902 – 1.04 0.393 990 3327 exclusion phecode
564.9 Personal history of diseases of digestive system Digestive 0.964 0.898 – 1.04 0.32 1030 3645 exclusion phecode
565 Anal and rectal conditions Digestive 1 0.943 – 1.07 0.883 1212 5239 exclusion phecode
565.1 Anal and rectal polyp Digestive 0.994 0.905 – 1.09 0.904 522 2405 exclusion phecode
567 Peritonitis and retroperitoneal infections Digestive 0.997 0.9 – 1.1 0.956 456 2047 exclusion phecode
568 Other disorders of peritoneum Digestive 0.989 0.897 – 1.09 0.829 471 2685 exclusion phecode
568.1
Peritoneal adhesions (postoperative)
Peritoneal adhesions (postoperative) (postinfection)
 Digestive 0.946 0.838 – 1.07 0.366 316 1918 exclusion phecode
569 Other disorders of intestine Digestive 0.997 0.952 – 1.04 0.891 2786 5893 exclusion phecode
569.1 Toxic gastroenteritis and colitis Digestive 1.08 0.882 – 1.33 0.441 114 537 exclusion phecode
569.2 Gastrointestinal complications Digestive 1.03 0.926 – 1.14 0.632 456 2294 exclusion phecode
571 Chronic liver disease and cirrhosis Digestive 1.01 0.954 – 1.07 0.75 1600 5284 exclusion phecode
571.5 Other chronic nonalcoholic liver disease Digestive 1 0.947 – 1.06 0.931 1506 5231 exclusion phecode
571.51 Cirrhosis of liver without mention of alcohol Digestive 1.07 0.963 – 1.19 0.21 406 1816 exclusion phecode
571.6 Primary biliary cirrhosis Digestive 0.941 0.731 – 1.21 0.635 77 325 exclusion phecode
571.8
Liver abscess and sequelae of chronic liver
Liver abscess and sequelae of chronic liver disease
 Digestive 1.12 0.999 – 1.25 0.053 377 1678 exclusion phecode
571.81 Portal hypertension Digestive 1.04 0.907 – 1.19 0.568 252 1014 exclusion phecode
572 Ascites (non malignant) Digestive 1.03 0.956 – 1.12 0.407 770 3606 exclusion phecode
573 Other disorders of liver Digestive 0.977 0.926 – 1.03 0.395 1837 5497 exclusion phecode
573.1 Chronic passive congestion of liver Digestive 0.987 0.752 – 1.3 0.925 92 227 exclusion phecode
573.2 Liver replaced by transplant Digestive 1.08 0.899 – 1.3 0.406 162 494 exclusion phecode
573.3 Hepatomegaly Digestive 0.903 0.756 – 1.08 0.263 137 880 exclusion phecode
573.4 Acute and subacute necrosis of liver Digestive 1.09 0.904 – 1.32 0.365 144 547 exclusion phecode
573.5 Jaundice (not of newborn) Digestive 0.996 0.89 – 1.12 0.95 375 1678 exclusion phecode
573.6
Nonspecific elevation of levels of transaminase
Nonspecific elevation of levels of transaminase or lactic acid dehydrogenase [LDH]
 Digestive 1.03 0.964 – 1.1 0.398 1180 4499 exclusion phecode
573.7 Abnormal results of function study of liver Digestive 1 0.942 – 1.07 0.945 1287 4674 exclusion phecode
573.9 Abnormal serum enzyme levels Digestive 1.04 0.986 – 1.09 0.15 1962 5555 exclusion phecode
574 Cholelithiasis and cholecystitis Digestive 0.965 0.906 – 1.03 0.277 1106 6052 exclusion phecode
574.1 Cholelithiasis Digestive 0.951 0.89 – 1.02 0.133 1022 5683 exclusion phecode
574.11 Cholelithiasis with acute cholecystitis Digestive 0.894 0.746 – 1.07 0.228 139 701 exclusion phecode
574.12 Cholelithiasis with other cholecystitis Digestive 1.03 0.875 – 1.2 0.757 180 1091 exclusion phecode
574.2 Calculus of bile duct Digestive 1.01 0.895 – 1.14 0.875 319 1705 exclusion phecode
574.3 Cholecystitis without cholelithiasis Digestive 0.974 0.867 – 1.1 0.664 325 1705 exclusion phecode
575 Other biliary tract disease Digestive 1 0.93 – 1.08 0.924 780 4392 exclusion phecode
575.1 Cholangitis Digestive 1.14 0.939 – 1.38 0.187 133 706 exclusion phecode
575.2 Obstruction of bile duct Digestive 1.02 0.876 – 1.2 0.767 192 1199 exclusion phecode
575.6 Cholesterolosis of gallbladder Digestive 0.945 0.728 – 1.23 0.673 62 381 exclusion phecode
575.7 Other disorders of gallbladder Digestive 0.945 0.845 – 1.06 0.32 352 1862 exclusion phecode
575.8 Other disorders of biliary tract Digestive 1.02 0.914 – 1.13 0.754 390 2254 exclusion phecode
575.9
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of biliary tract
 Digestive 0.987 0.794 – 1.23 0.905 106 523 exclusion phecode
577 Diseases of pancreas Digestive 1.01 0.938 – 1.09 0.74 768 4855 exclusion phecode
577.1 Acute pancreatitis Digestive 0.973 0.88 – 1.08 0.596 433 2674 exclusion phecode
577.2 Chronic pancreatitis Digestive 0.918 0.789 – 1.07 0.268 196 1081 exclusion phecode
577.3 Cyst and pseudocyst of pancreas Digestive 1.05 0.901 – 1.23 0.522 206 1299 exclusion phecode
578 Gastrointestinal hemorrhage Digestive 0.993 0.942 – 1.05 0.78 1857 6346 exclusion phecode
578.1 Hematemesis Digestive 1 0.864 – 1.16 0.986 220 913 exclusion phecode
578.2 Blood in stool Digestive 1 0.939 – 1.07 0.946 1165 4716 exclusion phecode
578.8 Hemorrhage of rectum and anus Digestive 1.01 0.937 – 1.09 0.807 899 3838 exclusion phecode
578.9 Hemorrhage of gastrointestinal tract Digestive 1.04 0.952 – 1.13 0.413 727 2824 exclusion phecode
579 Other symptoms involving abdomen and pelvis Digestive 1.01 0.952 – 1.07 0.781 1494 5792 exclusion phecode
579.2 Splenomegaly Digestive 1.07 0.944 – 1.21 0.296 335 1347 exclusion phecode
579.8 Nonspecific abnormal findings in stool contents Digestive 0.96 0.88 – 1.05 0.364 639 2641 exclusion phecode
580 Nephritis; nephrosis; renal sclerosis Genitourinary 1.09 1.02 – 1.17 0.0135 1099 2676 exclusion phecode
580.1 Glomerulonephritis Genitourinary 1.13 0.966 – 1.31 0.13 236 728 exclusion phecode
580.11 Proliferative glomerulonephritis Genitourinary 1.17 0.912 – 1.51 0.214 79 262 exclusion phecode
580.12 Non-proliferative glomerulonephritis Genitourinary 1.31 0.966 – 1.78 0.0818 64 208 exclusion phecode
580.13 Acute glomerulonephritis, NOS Genitourinary 1.05 0.723 – 1.51 0.814 38 117 exclusion phecode
580.14 Chronic glomerulonephritis, NOS Genitourinary 1.12 0.933 – 1.35 0.221 177 493 exclusion phecode
580.2
Nephrotic syndrome without mention of
Nephrotic syndrome without mention of glomerulonephritis
 Genitourinary 1.12 0.889 – 1.4 0.344 108 414 exclusion phecode
580.3
Nephritis and nephropathy without mention of
Nephritis and nephropathy without mention of glomerulonephritis
 Genitourinary 1.09 1.01 – 1.18 0.0252 953 2183 exclusion phecode
580.31
Nephritis and nephropathy in diseases
Nephritis and nephropathy in diseases classified elsewhere
 Genitourinary 1.07 0.983 – 1.17 0.113 723 1552 exclusion phecode
580.32
Nephritis and nephropathy with pathological
Nephritis and nephropathy with pathological lesion
 Genitourinary 1.14 1.01 – 1.28 0.0299 359 1276 exclusion phecode
580.4 Renal sclerosis, NOS Genitourinary 1.04 0.873 – 1.24 0.649 155 575 exclusion phecode
585 Renal failure Genitourinary 1.08 1.03 – 1.13 0.00198 2990 5042 exclusion phecode
585.1 Acute renal failure Genitourinary 1.09 1.03 – 1.15 0.00278 1961 4223 exclusion phecode
585.2 Renal failure NOS Genitourinary 1.07 0.963 – 1.2 0.203 459 1423 exclusion phecode
585.3 Chronic renal failure [CKD] Genitourinary 1.09 1.03 – 1.15 0.00184 2350 4621 exclusion phecode
585.31 Renal dialysis Genitourinary 1.11 0.998 – 1.24 0.0544 442 1294 exclusion phecode
585.32 End stage renal disease Genitourinary 1.11 1.01 – 1.22 0.0312 603 1693 exclusion phecode
585.33 Chronic Kidney Disease, Stage III Genitourinary 1.12 1.05 – 1.19 0.000299 1584 3459 exclusion phecode
585.34 Chronic Kidney Disease, Stage IV Genitourinary 1.1 0.993 – 1.21 0.0692 549 1599 exclusion phecode
585.4 Chronic kidney disease, Stage I or II Genitourinary 1.12 1.02 – 1.22 0.0137 694 2009 exclusion phecode
586 Other disorders of the kidney and ureters Genitourinary 1.06 1.01 – 1.11 0.0177 2675 5308 exclusion phecode
586.1 Anatomical abnormatilies of kidney and ureters Genitourinary 1.09 0.896 – 1.32 0.393 120 566 exclusion phecode
586.11 Small kidney Genitourinary 1.15 0.892 – 1.47 0.286 75 385 exclusion phecode
586.12 Vesicoureteral reflux Genitourinary 0.743 0.523 – 1.06 0.0989 42 196 exclusion phecode
586.2 Cyst of kidney, acquired Genitourinary 1.03 0.934 – 1.14 0.555 508 2087 exclusion phecode
586.3 Vascular disorders of kidney/hypertrophy Genitourinary 1.18 0.937 – 1.48 0.16 104 329 exclusion phecode
586.4 Stricture/obstruction of ureter Genitourinary 1.03 0.931 – 1.13 0.597 477 2567 exclusion phecode
587 Kidney replaced by transpant Genitourinary 1.1 0.988 – 1.22 0.0818 510 1394 exclusion phecode
588 Disorders resulting from impaired renal function Genitourinary 1.05 0.956 – 1.16 0.292 606 1691 exclusion phecode
588.1 Renal osteodystrophy Genitourinary 1.15 0.975 – 1.35 0.0978 206 479 exclusion phecode
588.2 Secondary hyperparathyroidism (of renal origin) Genitourinary 1.05 0.945 – 1.17 0.353 465 1396 exclusion phecode
589 Abnormal results of function study of kidney Genitourinary 1.13 1.02 – 1.25 0.0184 529 1706 exclusion phecode
590 Pyelonephritis Genitourinary 1.01 0.919 – 1.11 0.868 567 2369 exclusion phecode
591 Urinary tract infection Genitourinary 1.01 0.966 – 1.06 0.626 3173 5400 exclusion phecode
592 Cystitis and urethritis Genitourinary 1.05 0.981 – 1.13 0.161 1076 3953 exclusion phecode
592.1 Cystitis Genitourinary 1.06 0.987 – 1.14 0.108 1031 3789 exclusion phecode
592.11 Acute cystitis Genitourinary 1.07 0.98 – 1.16 0.138 718 2693 exclusion phecode
592.12 Chronic cystitis Genitourinary 0.842 0.66 – 1.07 0.167 78 397 exclusion phecode
592.13 Chronic interstitial cystitis Genitourinary 1.1 0.884 – 1.37 0.393 88 623 exclusion phecode
592.2 Urethritis and urethral syndrome Genitourinary 0.998 0.758 – 1.31 0.986 69 384 exclusion phecode
593 Hematuria Genitourinary 1.02 0.967 – 1.08 0.431 1752 5321 exclusion phecode
593.1 Gross hematuria Genitourinary 0.954 0.871 – 1.05 0.315 582 2752 exclusion phecode
593.2 Microscopic hematuria Genitourinary 1.04 0.937 – 1.16 0.453 410 1779 exclusion phecode
594 Urinary calculus Genitourinary 0.993 0.942 – 1.05 0.793 1735 7443 exclusion phecode
594.1 Calculus of kidney Genitourinary 0.991 0.939 – 1.05 0.749 1643 7407 exclusion phecode
594.2 Calculus of lower urinary tract Genitourinary 1.13 0.924 – 1.38 0.236 107 810 exclusion phecode
594.3 Calculus of ureter Genitourinary 0.965 0.873 – 1.07 0.488 444 2740 exclusion phecode
594.8 Renal colic Genitourinary 1.11 0.9 – 1.38 0.322 109 694 exclusion phecode
595 Hydronephrosis Genitourinary 0.923 0.836 – 1.02 0.112 463 3189 exclusion phecode
596 Other disorders of bladder Genitourinary 1.01 0.942 – 1.09 0.763 889 5593 exclusion phecode
596.1 Bladder neck obstruction Genitourinary 0.894 0.722 – 1.11 0.3 102 867 exclusion phecode
596.5 Functional disorders of bladder Genitourinary 1.03 0.936 – 1.12 0.592 551 3469 exclusion phecode
597 Other disorders of urethra and urinary tract Genitourinary 1.07 0.946 – 1.22 0.267 271 2411 exclusion phecode
597.1 Urethral stricture (not specified as infectious) Genitourinary 1.03 0.864 – 1.22 0.758 140 1307 exclusion phecode
597.2 Urinary complications NEC Genitourinary 1.04 0.915 – 1.18 0.548 257 2127 exclusion phecode
597.8 Urethral hypermobility/ISD Genitourinary 0.904 0.632 – 1.29 0.581 34 365 exclusion phecode
598 Abnormal findings on examination of urine Genitourinary 1.08 0.793 – 1.47 0.625 51 315 exclusion phecode
598.4 Other cells and casts in urine Genitourinary 1.07 0.765 – 1.49 0.701 44 285 exclusion phecode
599 Other symptoms/disorders or the urinary system Genitourinary 1 0.958 – 1.04 0.992 4132 5084 exclusion phecode
599.1 Urinary obstruction Genitourinary 0.937 0.818 – 1.07 0.346 256 1263 exclusion phecode
599.2 Retention of urine Genitourinary 0.994 0.934 – 1.06 0.839 1445 4497 exclusion phecode
599.3 Dysuria Genitourinary 0.997 0.94 – 1.06 0.914 1547 4655 exclusion phecode
599.4 Urinary incontinence Genitourinary 0.968 0.912 – 1.03 0.29 1516 4465 exclusion phecode
599.5 Frequency of urination and polyuria Genitourinary 1 0.946 – 1.06 0.999 1816 4848 exclusion phecode
599.6 Oliguria and anuria Genitourinary 1.04 0.914 – 1.19 0.548 289 942 exclusion phecode
599.7 Urethral discharge Genitourinary 0.814 0.585 – 1.13 0.224 41 285 exclusion phecode
599.8 Other symptoms involving urinary system Genitourinary 1.03 0.974 – 1.1 0.27 1574 4642 exclusion phecode
599.9 Other abnormality of urination Genitourinary 0.964 0.899 – 1.03 0.309 983 4214 exclusion phecode
600 Hyperplasia of prostate Genitourinary 0.933 0.868 – 1 0.0603 1479 2300 exclusion phecode
601 Inflammatory diseases of prostate Genitourinary 0.939 0.844 – 1.05 0.252 403 2012 exclusion phecode
601.1 Prostatitis Genitourinary 0.951 0.812 – 1.11 0.531 184 1034 exclusion phecode
601.11 Acute prostatitis Genitourinary 1.03 0.747 – 1.42 0.86 45 270 exclusion phecode
601.12 Chronic prostatitis Genitourinary 1.16 0.786 – 1.72 0.447 33 217 exclusion phecode
601.3 Orchitis and epididymitis Genitourinary 0.923 0.771 – 1.1 0.38 150 773 exclusion phecode
601.4 Balanoposthitis Genitourinary 0.878 0.629 – 1.23 0.444 47 238 exclusion phecode
601.8
Other inflammatory disorders of male genital
Other inflammatory disorders of male genital organs
 Genitourinary 1.06 0.812 – 1.37 0.684 69 311 exclusion phecode
602 Other disorders of prostate Genitourinary 0.894 0.733 – 1.09 0.268 115 734 exclusion phecode
602.3 Dysplasia of prostate Genitourinary 0.868 0.568 – 1.33 0.511 22 174 exclusion phecode
603 Other disorders of testis Genitourinary 0.822 0.688 – 0.981 0.0301 157 784 exclusion phecode
603.1 Hydrocele Genitourinary 0.801 0.646 – 0.993 0.0434 115 552 exclusion phecode
603.2 Spermatocele Genitourinary 0.821 0.615 – 1.1 0.183 59 270 exclusion phecode
604 Disorders of penis Genitourinary 0.922 0.797 – 1.07 0.277 221 1181 exclusion phecode
604.1 Redundant prepuce and phimosis/BXO Genitourinary 1.21 0.892 – 1.65 0.217 52 279 exclusion phecode
604.3 Peyronie's disease Genitourinary 0.632 0.465 – 0.859 0.00342 47 361 exclusion phecode
605 Erectile dysfunction [ED] Genitourinary 0.935 0.87 – 1 0.0652 1325 2135 exclusion phecode
608 Other disorders of male genital organs Genitourinary 0.896 0.817 – 0.983 0.0198 595 2271 exclusion phecode
609 Male infertility and abnormal spermatozoa Genitourinary 0.819 0.678 – 0.989 0.038 133 796 exclusion phecode
609.1 Infertility, male Genitourinary 0.8 0.633 – 1.01 0.0612 92 539 exclusion phecode
609.11 Azoospermia and oligospermia Genitourinary 0.827 0.553 – 1.24 0.357 26 168 exclusion phecode
609.2 Abnormal spermatozoa Genitourinary 0.876 0.654 – 1.17 0.372 48 302 exclusion phecode
610 Benign mammary dysplasias Genitourinary 0.916 0.85 – 0.987 0.0216 1011 2371 exclusion phecode
610.1 Cystic mastopathy Genitourinary 0.895 0.808 – 0.99 0.032 438 1978 exclusion phecode
610.2 Fibroadenosis of breast Genitourinary 0.872 0.54 – 1.41 0.575 25 90 exclusion phecode
610.4 Benign neoplasm of breast Genitourinary 0.937 0.863 – 1.02 0.123 778 2335 exclusion phecode
610.8 Other specified benign mammary dysplasias Genitourinary 0.893 0.792 – 1.01 0.0673 310 1661 exclusion phecode
611 Abnormal findings on mammogram or breast exam Genitourinary 0.923 0.869 – 0.98 0.00907 1907 2962 exclusion phecode
611.1 Abnormal mammogram Genitourinary 0.92 0.861 – 0.983 0.014 1526 2367 exclusion phecode
611.11 Mammographic microcalcification Genitourinary 0.895 0.801 – 1 0.0521 381 1477 exclusion phecode
611.3 Lump or mass in breast Genitourinary 0.919 0.857 – 0.985 0.0174 1145 2935 exclusion phecode
612
Breast conditions, congenital or relating to
Breast conditions, congenital or relating to hormones
 Genitourinary 0.907 0.802 – 1.03 0.118 307 1665 exclusion phecode
612.1 Galactorrhea Genitourinary 1 0.701 – 1.44 0.982 45 233 exclusion phecode
612.2 Hypertrophy of breast (Gynecomastia) Genitourinary 0.881 0.766 – 1.01 0.0774 226 1259 exclusion phecode
612.3 Congenital anomalies of breast Genitourinary 0.588 0.371 – 0.932 0.0237 30 124 exclusion phecode
613 Other nonmalignant breast conditions Genitourinary 0.962 0.901 – 1.03 0.258 1150 3967 exclusion phecode
613.1 Inflammatory disease of breast Genitourinary 0.989 0.835 – 1.17 0.899 163 1014 exclusion phecode
613.5 Mastodynia Genitourinary 0.922 0.841 – 1.01 0.0829 553 2939 exclusion phecode
613.7 Other signs and symptoms in breast Genitourinary 0.967 0.853 – 1.1 0.596 283 1583 exclusion phecode
613.8 Other specified disorders of breast Genitourinary 1.09 0.949 – 1.25 0.225 245 1580 exclusion phecode
613.9 Breast disorder NOS Genitourinary 0.926 0.832 – 1.03 0.154 394 2400 exclusion phecode
614 Inflammatory diseases of female pelvic organs Genitourinary 0.945 0.884 – 1.01 0.0974 1206 3285 exclusion phecode
614.1
Pelvic peritoneal adhesions, female
Pelvic peritoneal adhesions, female (postoperative) (postinfection)
 Genitourinary 0.947 0.74 – 1.21 0.666 81 534 exclusion phecode
614.3 Pelvic inflammatory disease (PID) Genitourinary 1.16 0.963 – 1.4 0.118 145 768 exclusion phecode
614.31 Acute inflammatory pelvic disease Genitourinary 1.4 0.838 – 2.33 0.2 24 139 exclusion phecode
614.32 Chronic inflammatory pelvic disease Genitourinary 1.12 0.817 – 1.53 0.487 54 257 exclusion phecode
614.33 Pelvic inflammatory disease, NOS Genitourinary 1.33 1.04 – 1.72 0.026 82 406 exclusion phecode
614.4 Inflammatory diseases of uterus, except cervix Genitourinary 1.21 0.887 – 1.64 0.232 56 291 exclusion phecode
614.5
Inflammatory disease of cervix, vagina, and
Inflammatory disease of cervix, vagina, and vulva
 Genitourinary 0.929 0.867 – 0.997 0.0398 1072 3257 exclusion phecode
614.51 Cervicitis and endocervicitis Genitourinary 0.87 0.697 – 1.09 0.217 83 476 exclusion phecode
614.52 Vaginitis and vulvovaginitis Genitourinary 0.925 0.859 – 0.996 0.0384 935 3148 exclusion phecode
614.53 Cyst or abscess of Bartholin's gland Genitourinary 1.05 0.751 – 1.47 0.774 45 266 exclusion phecode
614.54 Abscess or ulceration of vulva Genitourinary 1.01 0.797 – 1.29 0.905 73 423 exclusion phecode
615 Endometriosis Genitourinary 0.944 0.845 – 1.05 0.308 368 2372 exclusion phecode
618 Genital prolapse Genitourinary 0.962 0.874 – 1.06 0.433 459 3293 exclusion phecode
618.1 Prolapse of vaginal walls Genitourinary 0.904 0.8 – 1.02 0.106 275 2454 exclusion phecode
618.2 Uterine/Uterovaginal prolapse Genitourinary 0.94 0.78 – 1.13 0.518 122 970 exclusion phecode
618.5 Prolapse of vaginal vault after hysterectomy Genitourinary 0.994 0.722 – 1.37 0.971 38 538 exclusion phecode
618.6 Vaginal enterocele, congenital or acquired Genitourinary 1.09 0.89 – 1.33 0.414 108 769 exclusion phecode
619 Noninflammatory female genital disorders Genitourinary 0.943 0.887 – 1 0.0578 1639 3064 exclusion phecode
619.1
Noninflammatory disorders of ovary, fallopian
Noninflammatory disorders of ovary, fallopian tube, and broad ligament
 Genitourinary 0.874 0.777 – 0.984 0.0254 340 1890 exclusion phecode
619.2 Disorders of uterus, NEC Genitourinary 0.91 0.776 – 1.07 0.248 178 1004 exclusion phecode
619.3 Noninflammatory disorders of cervix Genitourinary 0.884 0.744 – 1.05 0.159 149 742 exclusion phecode
619.4 Noninflammatory disorders of vagina Genitourinary 0.957 0.884 – 1.04 0.271 811 2993 exclusion phecode
619.5 Noninflammatory disorders of vulva and perineum Genitourinary 1.02 0.916 – 1.14 0.711 384 2038 exclusion phecode
620 Dysplasia of female genital organs Genitourinary 1.02 0.829 – 1.24 0.879 115 694 exclusion phecode
620.1 Dysplasia of cervix Genitourinary 1.06 0.795 – 1.42 0.682 62 303 exclusion phecode
621 Endometrial hyperplasia Genitourinary 0.805 0.667 – 0.973 0.0249 131 671 exclusion phecode
622 Polyp of female genital organs Genitourinary 0.865 0.783 – 0.955 0.00398 466 2518 exclusion phecode
622.1 Polyp of corpus uteri Genitourinary 0.877 0.784 – 0.981 0.0216 360 1947 exclusion phecode
622.2 Mucous polyp of cervix Genitourinary 0.758 0.635 – 0.904 0.00206 150 783 exclusion phecode
623 Hypertrophy of female genital organs Genitourinary 0.972 0.861 – 1.1 0.653 292 1503 exclusion phecode
624 Symptoms involving female genital tract Genitourinary 0.956 0.862 – 1.06 0.392 450 1952 exclusion phecode
624.1 Dystrophy of female genital tract Genitourinary 0.888 0.684 – 1.15 0.374 66 378 exclusion phecode
624.2 Atrophy of female genital tract Genitourinary 1.26 0.791 – 2.02 0.329 18 133 exclusion phecode
624.9 stress incontinence, female Genitourinary 0.976 0.885 – 1.08 0.622 491 2341 exclusion phecode
625
Pain and other symptoms associated with female
Pain and other symptoms associated with female genital organs
 Genitourinary 0.91 0.855 – 0.969 0.00313 1662 2683 exclusion phecode
625.1 Dyspareunia Genitourinary 1.01 0.894 – 1.14 0.892 322 1786 exclusion phecode
626
Disorders of menstruation and other abnormal
Disorders of menstruation and other abnormal bleeding from female genital tract
 Genitourinary 0.918 0.86 – 0.981 0.0111 1836 2105 exclusion phecode
626.1 Irregular menstrual cycle/bleeding Genitourinary 0.913 0.851 – 0.98 0.0115 1477 1944 exclusion phecode
626.11 Absent or infrequent menstruation Genitourinary 0.943 0.84 – 1.06 0.321 378 1137 exclusion phecode
626.12 Excessive or frequent menstruation Genitourinary 0.875 0.8 – 0.956 0.00324 745 1543 exclusion phecode
626.13 Irregular menstrual cycle Genitourinary 0.924 0.844 – 1.01 0.0865 697 1626 exclusion phecode
626.14 Irregular menstrual bleeding Genitourinary 0.912 0.811 – 1.03 0.123 364 1148 exclusion phecode
626.15 Infertility, female, associated with anovulation Genitourinary 1.1 0.915 – 1.31 0.32 156 591 exclusion phecode
626.2 Dysmenorrhea Genitourinary 0.946 0.845 – 1.06 0.33 437 1253 exclusion phecode
626.4 Premenstrual tension syndromes Genitourinary 0.919 0.753 – 1.12 0.404 121 469 exclusion phecode
626.8 Infertility, female Genitourinary 1.11 0.972 – 1.27 0.122 285 885 exclusion phecode
627 Menopausal and postmenopausal disorders Genitourinary 0.838 0.781 – 0.899 7.83e-07 1348 1938 exclusion phecode
627.1 Postmenopausal bleeding Genitourinary 0.812 0.723 – 0.913 0.00048 334 1413 exclusion phecode
627.2 Symptomatic menopause Genitourinary 0.85 0.784 – 0.921 7.85e-05 896 1823 exclusion phecode
627.21 Symptomatic artificial menopause Genitourinary 0.807 0.605 – 1.08 0.143 54 199 exclusion phecode
627.22
Need for Hormone replacement therapy
Need for Hormone replacement therapy (postmenopausal)
 Genitourinary 0.94 0.763 – 1.16 0.558 98 564 exclusion phecode
627.3 Postmenopausal atrophic vaginitis Genitourinary 0.878 0.776 – 0.992 0.0375 303 1325 exclusion phecode
627.4 Premenopausal menorrhagia Genitourinary 0.979 0.813 – 1.18 0.822 131 505 exclusion phecode
627.5 Premature menopause and other ovarian failure Genitourinary 0.76 0.615 – 0.94 0.0115 96 428 exclusion phecode
628 Ovarian cyst Genitourinary 0.895 0.815 – 0.982 0.0194 606 1825 exclusion phecode
634 Miscarriage; stillbirth Pregnancy Complications 1.08 0.942 – 1.23 0.283 280 1469 exclusion phecode
634.1 Missed abortion/Hydatidiform mole Pregnancy Complications 0.977 0.782 – 1.22 0.838 99 550 exclusion phecode
634.3 Ectopic pregnancy Pregnancy Complications 1.06 0.735 – 1.52 0.76 36 215 exclusion phecode
635
Hemorrhage during pregnancy; childbirth and
Hemorrhage during pregnancy; childbirth and postpartum
 Pregnancy Complications 1.15 0.983 – 1.34 0.0812 199 1002 exclusion phecode
635.2
Antepartum hemorrhage, abruptio placentae, and
Antepartum hemorrhage, abruptio placentae, and placenta previa
 Pregnancy Complications 1.18 0.978 – 1.42 0.0849 141 691 exclusion phecode
635.3 Placenta previa and abruptio placenta Pregnancy Complications 1.05 0.848 – 1.3 0.647 94 550 exclusion phecode
636
Early or threatened labor; hemorrhage in early
Early or threatened labor; hemorrhage in early pregnancy
 Pregnancy Complications 1.03 0.914 – 1.16 0.637 378 1470 exclusion phecode
636.1 Threatened premature labor Pregnancy Complications 1.03 0.848 – 1.24 0.788 139 682 exclusion phecode
636.2 Early onset of delivery Pregnancy Complications 0.939 0.766 – 1.15 0.543 119 552 exclusion phecode
636.3 Hemorrhage in early pregnancy Pregnancy Complications 1.14 0.955 – 1.36 0.148 165 825 exclusion phecode
636.8 Cervical incompetence Pregnancy Complications 0.951 0.583 – 1.55 0.842 24 154 exclusion phecode
637
Short gestation; low birth weight; and fetal
Short gestation; low birth weight; and fetal growth retardation
 Pregnancy Complications 1.29 0.869 – 1.92 0.206 33 159 exclusion phecode
642
Hypertension complicating pregnancy
Hypertension complicating pregnancy, childbirth, and the puerperium
 Pregnancy Complications 1.12 0.951 – 1.32 0.173 193 1228 exclusion phecode
642.1 Preeclampsia and eclampsia Pregnancy Complications 1.12 0.907 – 1.39 0.285 109 682 exclusion phecode
643 Excessive vomiting in pregnancy Pregnancy Complications 0.956 0.769 – 1.19 0.689 91 560 exclusion phecode
643.1 Hyperemesis gravidarum Pregnancy Complications 0.938 0.667 – 1.32 0.711 43 257 exclusion phecode
644 Anemia during pregnancy Pregnancy Complications 0.889 0.703 – 1.12 0.325 80 512 exclusion phecode
646 Other complications of pregnancy NEC Pregnancy Complications 1.05 0.916 – 1.21 0.475 269 1266 exclusion phecode
647
Infectious and parasitic complications
Infectious and parasitic complications affecting pregnancy
 Pregnancy Complications 1.02 0.789 – 1.31 0.897 72 488 exclusion phecode
647.1
Infections of genitourinary tract during
Infections of genitourinary tract during pregnancy
 Pregnancy Complications 0.961 0.748 – 1.23 0.755 78 464 exclusion phecode
647.3 Major puerperal infection Pregnancy Complications 0.974 0.601 – 1.58 0.914 18 151 exclusion phecode
649
Other conditions or status of the mother
Other conditions or status of the mother complicating pregnancy, childbirth, or the puerperium
 Pregnancy Complications 1.06 0.945 – 1.19 0.322 424 1499 exclusion phecode
649.1
Diabetes or abnormal glucose tolerance
Diabetes or abnormal glucose tolerance complicating pregnancy
 Pregnancy Complications 1.01 0.887 – 1.16 0.841 263 1303 exclusion phecode
653
Problems associated with amniotic cavity and
Problems associated with amniotic cavity and membranes
 Pregnancy Complications 0.976 0.836 – 1.14 0.755 199 1105 exclusion phecode
654.1
Abnormality of organs and soft tissues of
Abnormality of organs and soft tissues of pelvis complicating pregnancy, childbirth, or the puerperium
 Pregnancy Complications 1.12 0.858 – 1.46 0.409 70 402 exclusion phecode
654.2 Rhesus isoimmunization in pregnancy Pregnancy Complications 1.12 0.858 – 1.47 0.395 76 410 exclusion phecode
655
Known or suspected fetal abnormality affecting
Known or suspected fetal abnormality affecting management of mother
 Pregnancy Complications 1.06 0.963 – 1.17 0.229 547 1875 exclusion phecode
655.1 Abnormality in fetal heart rate or rhythm Pregnancy Complications 1.07 0.922 – 1.25 0.366 225 1051 exclusion phecode
656 Other perinatal conditions of fetus or newborn Pregnancy Complications 1.08 0.948 – 1.23 0.25 300 1362 exclusion phecode
656.2 Respiratory conditions of fetus and newborn Pregnancy Complications 0.983 0.627 – 1.54 0.941 24 143 exclusion phecode
669 Complications of labor and delivery NEC Pregnancy Complications 1.06 0.935 – 1.21 0.345 304 1347 exclusion phecode
671
Venous/cerebrovascular complications embolism
Venous/cerebrovascular complications embolism in pregnancy and the puerperium
 Pregnancy Complications 0.993 0.767 – 1.28 0.955 72 445 exclusion phecode
674 Other complications of the puerperium NEC Pregnancy Complications 0.986 0.733 – 1.33 0.926 49 343 exclusion phecode
676
Other disorders of the breast associated with
Other disorders of the breast associated with childbirth and disorders of lactation
 Pregnancy Complications 0.979 0.758 – 1.26 0.869 83 404 exclusion phecode
681 Superficial cellulitis and abscess Dermatologic 0.986 0.94 – 1.03 0.544 2423 6666 exclusion phecode
681.1 Cellulitis and abscess of fingers/toes Dermatologic 1.01 0.925 – 1.1 0.841 637 2566 exclusion phecode
681.2 Cellulitis and abscess of face/neck Dermatologic 1.06 0.94 – 1.19 0.363 343 1895 exclusion phecode
681.3 Cellulitis and abscess of arm/hand Dermatologic 0.991 0.923 – 1.06 0.797 969 3791 exclusion phecode
681.5 Cellulitis and abscess of leg, except foot Dermatologic 1.01 0.939 – 1.08 0.873 1048 3951 exclusion phecode
681.6 Cellulitis and abscess of foot, toe Dermatologic 1.02 0.95 – 1.1 0.543 867 3321 exclusion phecode
681.7 Cellulitis and abscess of trunk Dermatologic 0.966 0.885 – 1.05 0.445 584 2935 exclusion phecode
686
Other local infections of skin and subcutaneous
Other local infections of skin and subcutaneous tissue
 Dermatologic 1.03 0.957 – 1.11 0.431 872 4006 exclusion phecode
686.1 Carbuncle and furuncle Dermatologic 1.06 0.919 – 1.23 0.408 226 1160 exclusion phecode
686.2 Impetigo Dermatologic 0.929 0.784 – 1.1 0.4 165 827 exclusion phecode
686.3 Pilonidal cyst Dermatologic 1.01 0.759 – 1.35 0.931 55 366 exclusion phecode
686.4 Pyogenic granuloma Dermatologic 0.861 0.628 – 1.18 0.355 49 270 exclusion phecode
686.5 Pyoderma Dermatologic 1.12 0.752 – 1.68 0.57 25 132 exclusion phecode
687 Symptoms affecting skin Dermatologic 0.93 0.856 – 1.01 0.0867 683 2902 exclusion phecode
687.1 Rash and other nonspecific skin eruption Dermatologic 0.935 0.893 – 0.98 0.0052 2662 5505 exclusion phecode
687.3 Changes in skin texture Dermatologic 0.935 0.803 – 1.09 0.389 194 947 exclusion phecode
687.4 Disturbance of skin sensation Dermatologic 0.93 0.884 – 0.978 0.00501 2143 5453 exclusion phecode
689 Disorder of skin and subcutaneous tissue NOS Dermatologic 0.978 0.936 – 1.02 0.301 3310 6350 exclusion phecode
690 Erythematosquamous dermatosis Dermatologic 0.931 0.884 – 0.98 0.00615 2038 5496 exclusion phecode
690.1 Seborrheic dermatitis Dermatologic 0.931 0.885 – 0.98 0.00635 2037 5491 exclusion phecode
691 Congenital anomalies of skin Dermatologic 0.903 0.777 – 1.05 0.182 204 972 exclusion phecode
691.3 Congenital pigmentary anomalies of skin Dermatologic 1 0.583 – 1.73 0.99 14 99 exclusion phecode
694 Dyschromia and Vitiligo Dermatologic 0.919 0.846 – 0.999 0.0471 661 3213 exclusion phecode
694.1 Vitiligo Dermatologic 1.06 0.812 – 1.39 0.66 54 313 exclusion phecode
694.2 Other dyschromia Dermatologic 0.888 0.813 – 0.97 0.00861 579 2868 exclusion phecode
694.3 Vascular disorders of skin Dermatologic 1.46 0.995 – 2.15 0.0528 40 136 exclusion phecode
695 Erythematous conditions Dermatologic 0.921 0.869 – 0.976 0.00547 1480 5252 exclusion phecode
695.1 Toxic erythema Dermatologic 0.781 0.529 – 1.15 0.212 25 144 exclusion phecode
695.2 Bullous dermatoses Dermatologic 1.08 0.709 – 1.65 0.72 32 141 exclusion phecode
695.3 Rosacea Dermatologic 0.882 0.811 – 0.959 0.00324 643 3142 exclusion phecode
695.4 Lupus (localized and systemic) Dermatologic 1.05 0.901 – 1.22 0.552 210 1010 exclusion phecode
695.41 Cutaneous lupus erythematosus Dermatologic 1.03 0.817 – 1.3 0.795 89 362 exclusion phecode
695.42 Systemic lupus erythematosus Dermatologic 1.03 0.878 – 1.2 0.745 195 960 exclusion phecode
695.7 Prurigo and Lichen Dermatologic 0.932 0.804 – 1.08 0.348 210 1113 exclusion phecode
695.8 Other specified erythematous conditions Dermatologic 0.94 0.84 – 1.05 0.284 358 1531 exclusion phecode
695.81 Erythema nodosum Dermatologic 0.697 0.419 – 1.16 0.166 23 82 exclusion phecode
695.9 Unspecified erythematous condition Dermatologic 0.975 0.854 – 1.11 0.713 266 1310 exclusion phecode
696 Psoriasis and related disorders Dermatologic 0.917 0.828 – 1.01 0.0925 432 2464 exclusion phecode
696.3 Pityriasis Dermatologic 0.869 0.598 – 1.26 0.459 28 151 exclusion phecode
696.4 Psoriasis Dermatologic 0.919 0.827 – 1.02 0.116 404 2354 exclusion phecode
696.41 Psoriasis vulgaris Dermatologic 0.912 0.818 – 1.02 0.0946 383 2180 exclusion phecode
696.42 Psoriatic arthropathy Dermatologic 1.07 0.856 – 1.33 0.565 90 499 exclusion phecode
697 Sarcoidosis Dermatologic 0.976 0.789 – 1.21 0.821 95 618 exclusion phecode
698 Pruritus and related conditions Dermatologic 1.02 0.945 – 1.09 0.659 859 4437 exclusion phecode
700 Corns and callosities Dermatologic 1.01 0.929 – 1.09 0.854 798 2369 exclusion phecode
701
Other hypertrophic and atrophic conditions of
Other hypertrophic and atrophic conditions of skin
 Dermatologic 0.985 0.94 – 1.03 0.515 2543 6601 exclusion phecode
701.1 Keratoderma, acquired Dermatologic 0.973 0.845 – 1.12 0.702 246 1144 exclusion phecode
701.2 Scar conditions and fibrosis of skin Dermatologic 0.934 0.853 – 1.02 0.136 522 3590 exclusion phecode
701.3 Circumscribed scleroderma Dermatologic 0.957 0.812 – 1.13 0.6 168 970 exclusion phecode
701.4 Keloid scar Dermatologic 1.06 0.901 – 1.25 0.469 166 1007 exclusion phecode
701.5 Abnormal granulation tissue Dermatologic 0.86 0.706 – 1.05 0.137 120 729 exclusion phecode
702
Degenerative skin conditions and other
Degenerative skin conditions and other dermatoses
 Dermatologic 0.959 0.913 – 1.01 0.101 2633 4726 exclusion phecode
702.1 Actinic keratosis Dermatologic 0.951 0.897 – 1.01 0.0861 1653 4703 exclusion phecode
702.2 Seborrheic keratosis Dermatologic 0.951 0.903 – 1 0.0542 2123 5690 exclusion phecode
702.4 Degenerative skin disorders Dermatologic 1.29 0.918 – 1.82 0.142 32 188 exclusion phecode
703 Diseases of nail, NOS Dermatologic 1.02 0.945 – 1.1 0.595 823 3258 exclusion phecode
703.1 Ingrowing nail Dermatologic 0.984 0.889 – 1.09 0.762 459 2072 exclusion phecode
704 Diseases of hair and hair follicles Dermatologic 0.954 0.895 – 1.02 0.144 1140 5585 exclusion phecode
704.1 Alopecia Dermatologic 0.931 0.843 – 1.03 0.157 466 2499 exclusion phecode
704.11 Alopecia Areata Dermatologic 1 0.687 – 1.47 0.982 31 165 exclusion phecode
704.12 Telogen effluvium Dermatologic 0.639 0.383 – 1.07 0.0873 24 89 exclusion phecode
704.2 Hirsutism Dermatologic 0.976 0.787 – 1.21 0.826 102 570 exclusion phecode
704.8
Other specified diseases of hair and hair
Other specified diseases of hair and hair follicles
 Dermatologic 0.99 0.913 – 1.07 0.814 699 3629 exclusion phecode
705 Disorders of sweat glands Dermatologic 1.04 0.89 – 1.21 0.633 218 1118 exclusion phecode
705.1 Dyshidrosis Dermatologic 0.957 0.729 – 1.26 0.75 65 290 exclusion phecode
705.3 Hidradenitis Dermatologic 1.12 0.862 – 1.44 0.404 79 423 exclusion phecode
705.8 Hyperhidrosis Dermatologic 1.02 0.917 – 1.13 0.725 450 2123 exclusion phecode
706 Diseases of sebaceous glands Dermatologic 0.967 0.923 – 1.01 0.166 2355 6941 exclusion phecode
706.1 Acne Dermatologic 0.986 0.916 – 1.06 0.698 956 4030 exclusion phecode
706.2 Sebaceous cyst Dermatologic 0.96 0.899 – 1.03 0.228 1086 4960 exclusion phecode
706.3 Seborrhea Dermatologic 1.1 0.705 – 1.72 0.668 28 121 exclusion phecode
706.8 Other specified diseases of sebaceous glands Dermatologic 0.926 0.857 – 1 0.0527 783 3173 exclusion phecode
707 Chronic ulcer of skin Dermatologic 1.05 0.985 – 1.12 0.135 1181 5443 exclusion phecode
707.1 Decubitus ulcer Dermatologic 1.05 0.938 – 1.19 0.371 362 1773 exclusion phecode
707.2 Chronic ulcer of leg or foot Dermatologic 1.04 0.953 – 1.14 0.372 624 2446 exclusion phecode
707.3 Chronic ulcer of unspecified site Dermatologic 1.05 0.962 – 1.14 0.279 605 3452 exclusion phecode
709 Diffuse diseases of connective tissue Dermatologic 1.05 0.948 – 1.15 0.373 499 2493 exclusion phecode
709.2 Sicca syndrome Dermatologic 1.05 0.886 – 1.24 0.588 164 801 exclusion phecode
709.3 Systemic sclerosis Dermatologic 0.971 0.768 – 1.23 0.809 81 360 exclusion phecode
709.5 Dermatomyositis Dermatologic 1.17 0.807 – 1.68 0.415 34 173 exclusion phecode
709.6
Other specified diffuse diseases of connective
Other specified diffuse diseases of connective tissue
 Dermatologic 0.739 0.506 – 1.08 0.118 34 111 exclusion phecode
709.7 Unspecified diffuse connective tissue disease Dermatologic 1.07 0.946 – 1.2 0.29 321 1627 exclusion phecode
710
Osteomyelitis, periostitis, and other
Osteomyelitis, periostitis, and other infections involving bone
 Musculoskeletal 1.02 0.928 – 1.13 0.629 464 2238 exclusion phecode
710.1 Osteomyelitis Musculoskeletal 1.04 0.937 – 1.15 0.49 453 2162 exclusion phecode
710.11 Acute osteomyelitis Musculoskeletal 1.06 0.928 – 1.21 0.386 274 1196 exclusion phecode
710.12 Chronic osteomyelitis Musculoskeletal 1 0.871 – 1.16 0.955 218 1083 exclusion phecode
710.19 Unspecified osteomyelitis Musculoskeletal 1.03 0.93 – 1.14 0.553 430 2084 exclusion phecode
711 Arthropathy associated with infections Musculoskeletal 0.903 0.755 – 1.08 0.26 153 707 exclusion phecode
711.1 Pyogenic arthritis Musculoskeletal 0.962 0.783 – 1.18 0.711 113 515 exclusion phecode
712 Infective connective tissue disorders Musculoskeletal 1.02 0.817 – 1.29 0.831 79 309 exclusion phecode
713
Arthropathy associated with other disorders
Arthropathy associated with other disorders classified elsewhere
 Musculoskeletal 1.07 0.9 – 1.26 0.461 175 827 exclusion phecode
713.5
Arthropathy associated with neurological
Arthropathy associated with neurological disorders
 Musculoskeletal 1.08 0.894 – 1.31 0.422 133 621 exclusion phecode
714
Rheumatoid arthritis and other inflammatory
Rheumatoid arthritis and other inflammatory polyarthropathies
 Musculoskeletal 1.01 0.931 – 1.1 0.76 652 3231 exclusion phecode
714.1 Rheumatoid arthritis Musculoskeletal 1.02 0.925 – 1.12 0.703 492 2594 exclusion phecode
714.2 Juvenile rheumatoid arthritis Musculoskeletal 1.26 0.816 – 1.96 0.293 23 166 exclusion phecode
715 Other inflammatory spondylopathies Musculoskeletal 0.937 0.843 – 1.04 0.226 423 2084 exclusion phecode
715.1 Sacroiliitis NEC Musculoskeletal 1.06 0.849 – 1.31 0.628 94 448 exclusion phecode
715.2 Ankylosing spondylitis Musculoskeletal 0.822 0.624 – 1.08 0.165 51 378 exclusion phecode
716 Other arthropathies Musculoskeletal 0.96 0.918 – 1 0.0736 3704 5406 exclusion phecode
716.1 Unspecified polyarthropathy or polyarthritis Musculoskeletal 0.88 0.687 – 1.13 0.314 76 348 exclusion phecode
716.2 Unspecified monoarthritis Musculoskeletal 0.796 0.588 – 1.08 0.139 44 207 exclusion phecode
716.9 Arthropathy NOS Musculoskeletal 0.959 0.917 – 1 0.068 3674 5405 exclusion phecode
717 Polymyalgia Rheumatica Musculoskeletal 1.13 0.899 – 1.41 0.303 90 653 exclusion phecode
720 Spinal stenosis Musculoskeletal 0.955 0.896 – 1.02 0.159 1244 4947 exclusion phecode
720.1 Spinal stenosis of lumbar region Musculoskeletal 0.94 0.875 – 1.01 0.0903 965 4132 exclusion phecode
721 Spondylosis and allied disorders Musculoskeletal 0.956 0.907 – 1.01 0.099 1895 5752 exclusion phecode
721.1 Spondylosis without myelopathy Musculoskeletal 0.948 0.898 – 1 0.0519 1801 5681 exclusion phecode
721.2 Spondylosis with myelopathy Musculoskeletal 0.941 0.823 – 1.08 0.373 248 1513 exclusion phecode
721.8 Other allied disorders of spine Musculoskeletal 0.821 0.659 – 1.02 0.0785 100 534 exclusion phecode
722 Intervertebral disc disorders Musculoskeletal 0.945 0.897 – 0.997 0.0369 1910 6009 exclusion phecode
722.1 Displacement of intervertebral disc Musculoskeletal 0.961 0.9 – 1.03 0.236 1084 5472 exclusion phecode
722.3 Schmorl's nodes Musculoskeletal 0.734 0.512 – 1.05 0.0925 48 184 exclusion phecode
722.6 Degeneration of intervertebral disc Musculoskeletal 0.939 0.883 – 0.999 0.045 1309 5423 exclusion phecode
722.7 Intervertebral disc disorder with myelopathy Musculoskeletal 1.01 0.839 – 1.21 0.931 133 829 exclusion phecode
722.8 Postlaminectomy syndrome Musculoskeletal 1.25 1.02 – 1.53 0.0315 112 731 exclusion phecode
722.9 Other and unspecified disc disorder Musculoskeletal 0.941 0.861 – 1.03 0.177 561 3499 exclusion phecode
723 Other disorders of cervical region Musculoskeletal 0.997 0.881 – 1.13 0.959 309 1688 exclusion phecode
723.1 Torticollis Musculoskeletal 1.03 0.806 – 1.31 0.825 80 450 exclusion phecode
724 Other and unspecified disorders of back Musculoskeletal 0.946 0.891 – 1 0.0684 1373 5691 exclusion phecode
724.1 Disorders of sacrum Musculoskeletal 0.936 0.868 – 1.01 0.0856 820 3945 exclusion phecode
724.2 Disorders of coccyx Musculoskeletal 0.869 0.736 – 1.03 0.1 173 792 exclusion phecode
724.8 Other symptoms referable to back Musculoskeletal 0.89 0.791 – 1 0.052 334 1677 exclusion phecode
724.9 Other unspecified back disorders Musculoskeletal 1.01 0.907 – 1.12 0.889 397 2387 exclusion phecode
726 Peripheral enthesopathies and allied syndromes Musculoskeletal 0.922 0.881 – 0.966 0.000573 3469 4264 exclusion phecode
726.1 Enthesopathy Musculoskeletal 0.918 0.873 – 0.966 0.000951 2574 4247 exclusion phecode
726.2 Synoviopathy Musculoskeletal 0.865 0.772 – 0.969 0.0124 361 1468 exclusion phecode
726.3 Bursitis Musculoskeletal 0.898 0.828 – 0.974 0.00909 753 2501 exclusion phecode
726.4 Calcaneal spur; Exostosis NOS Musculoskeletal 0.906 0.814 – 1.01 0.0721 421 1729 exclusion phecode
727 Other disorders of synovium, tendon, and bursa Musculoskeletal 0.915 0.87 – 0.963 0.000601 2554 4242 exclusion phecode
727.1 Synovitis and tenosynovitis Musculoskeletal 0.925 0.864 – 0.989 0.0228 1146 3539 exclusion phecode
727.2 Bursitis disorders Musculoskeletal 0.902 0.753 – 1.08 0.262 157 632 exclusion phecode
727.4 Ganglion and cyst of synovium, tendon, and bursa Musculoskeletal 0.924 0.838 – 1.02 0.109 498 2040 exclusion phecode
727.5 Rupture of synovium Musculoskeletal 0.821 0.689 – 0.978 0.0272 153 652 exclusion phecode
727.6 Rupture of tendon, nontraumatic Musculoskeletal 0.883 0.819 – 0.953 0.00138 872 3042 exclusion phecode
727.7 Contracture of tendon (sheath) Musculoskeletal 0.903 0.762 – 1.07 0.239 156 846 exclusion phecode
727.8 Plica syndrome Musculoskeletal 1.09 0.722 – 1.64 0.692 35 147 exclusion phecode
728 Disorders of muscle, ligament, and fascia Musculoskeletal 0.963 0.907 – 1.02 0.209 1559 4115 exclusion phecode
728.1 Muscular calcification and ossification Musculoskeletal 1.02 0.658 – 1.57 0.937 27 132 exclusion phecode
728.2 Laxity of ligament or hypermobility syndrome Musculoskeletal 0.885 0.707 – 1.11 0.284 100 409 exclusion phecode
728.7 Fasciitis Musculoskeletal 0.942 0.88 – 1.01 0.0837 1095 3372 exclusion phecode
728.71
Contracture of palmar fascia [Dupuytren's
Contracture of palmar fascia [Dupuytren's disease]
 Musculoskeletal 0.97 0.826 – 1.14 0.708 171 765 exclusion phecode
729 Other disorders of soft tissues Musculoskeletal 0.978 0.919 – 1.04 0.495 1390 3823 exclusion phecode
729.1 Rheumatism, unspecified and fibrositis Musculoskeletal 0.813 0.545 – 1.21 0.311 30 116 exclusion phecode
729.3 Panniculitis Musculoskeletal 1.36 0.935 – 1.98 0.107 43 170 exclusion phecode
729.7 Nontraumatic compartment syndrome Musculoskeletal 0.638 0.395 – 1.03 0.0666 19 100 exclusion phecode
731
Osteitis deformans and osteopathies associated
Osteitis deformans and osteopathies associated with other disorders classified elsewhere
 Musculoskeletal 0.972 0.783 – 1.21 0.798 118 540 exclusion phecode
732 Osteochondropathies Musculoskeletal 0.991 0.799 – 1.23 0.937 93 587 exclusion phecode
732.1 Juvenile osteochondrosis Musculoskeletal 0.975 0.736 – 1.29 0.858 58 359 exclusion phecode
732.7 Osteochondritis dissecans Musculoskeletal 1.01 0.678 – 1.5 0.964 28 131 exclusion phecode
733 Other disorders of bone and cartilage Musculoskeletal 0.982 0.924 – 1.04 0.546 1511 4778 exclusion phecode
733.2 Cyst of bone Musculoskeletal 1.17 0.853 – 1.6 0.33 46 321 exclusion phecode
733.4 Aseptic necrosis of bone Musculoskeletal 0.926 0.77 – 1.11 0.416 124 847 exclusion phecode
733.6 Costochondritis Musculoskeletal 1.05 0.856 – 1.28 0.645 118 625 exclusion phecode
733.8 Malunion and nonunion of fracture Musculoskeletal 0.95 0.812 – 1.11 0.516 163 1288 exclusion phecode
733.9 Chondromalacia Musculoskeletal 1.27 0.795 – 2.03 0.318 16 133 exclusion phecode
735 Acquired foot deformities Musculoskeletal 0.985 0.928 – 1.04 0.606 1362 5729 exclusion phecode
735.1 Flat foot Musculoskeletal 1.09 0.951 – 1.25 0.216 257 1319 exclusion phecode
735.2 Acquired toe deformities Musculoskeletal 0.981 0.899 – 1.07 0.659 617 2701 exclusion phecode
735.21 Hammer toe (acquired) Musculoskeletal 0.969 0.873 – 1.08 0.551 433 1891 exclusion phecode
735.23 Hallux rigidus Musculoskeletal 0.924 0.771 – 1.11 0.39 134 818 exclusion phecode
735.3 Hallux valgus (Bunion) Musculoskeletal 0.895 0.818 – 0.98 0.0163 556 2948 exclusion phecode
736 Other acquired deformities of limbs Musculoskeletal 0.971 0.905 – 1.04 0.405 941 5091 exclusion phecode
736.1 Acquired deformities of forearm Musculoskeletal 0.693 0.442 – 1.08 0.108 31 163 exclusion phecode
736.2 Acquired deformities of finger Musculoskeletal 1.04 0.806 – 1.35 0.745 71 415 exclusion phecode
736.3 Acquired deformities of hip Musculoskeletal 1.15 0.646 – 2.06 0.63 15 89 exclusion phecode
736.4 Genu valgum or varum (acquired) Musculoskeletal 0.899 0.723 – 1.12 0.338 93 559 exclusion phecode
736.5 Acquired deformities of knee Musculoskeletal 0.851 0.667 – 1.09 0.194 70 446 exclusion phecode
736.6 Unequal leg length (acquired) Musculoskeletal 0.995 0.814 – 1.22 0.961 110 592 exclusion phecode
737 Curvature of spine Musculoskeletal 0.922 0.834 – 1.02 0.116 439 2706 exclusion phecode
737.1 Kyphosis (acquired) Musculoskeletal 0.954 0.791 – 1.15 0.626 128 819 exclusion phecode
737.2 Lordosis (acquired) Musculoskeletal 1.04 0.639 – 1.69 0.874 17 120 exclusion phecode
737.3 Kyphoscoliosis and scoliosis Musculoskeletal 0.913 0.815 – 1.02 0.118 339 2030 exclusion phecode
738 Other acquired musculoskeletal deformity Musculoskeletal 0.978 0.897 – 1.07 0.615 574 4223 exclusion phecode
738.4 Acquired spondylolisthesis Musculoskeletal 1 0.887 – 1.14 0.941 291 1879 exclusion phecode
739 Contracture of joint Musculoskeletal 0.802 0.687 – 0.937 0.00542 185 1187 exclusion phecode
740 Osteoarthrosis Musculoskeletal 0.956 0.914 – 0.999 0.0434 4442 5120 exclusion phecode
740.1 Osteoarthritis; localized Musculoskeletal 0.937 0.889 – 0.989 0.0175 2371 4554 exclusion phecode
740.11 Osteoarthrosis, localized, primary Musculoskeletal 0.929 0.879 – 0.981 0.00861 2111 4391 exclusion phecode
740.12 Osteoarthrosis, localized, secondary Musculoskeletal 0.963 0.832 – 1.11 0.613 217 1170 exclusion phecode
740.2 Osteoarthrosis, generalized Musculoskeletal 0.94 0.857 – 1.03 0.193 659 2000 exclusion phecode
740.3
Osteoarthrosis involving more than one site
Osteoarthrosis involving more than one site, but not specified as generalized
 Musculoskeletal 0.881 0.732 – 1.06 0.18 150 524 exclusion phecode
740.9 Osteoarthrosis NOS Musculoskeletal 0.959 0.918 – 1 0.0685 4266 5093 exclusion phecode
741 Symptoms and disorders of the joints Musculoskeletal 0.976 0.933 – 1.02 0.305 2781 6258 exclusion phecode
741.1 Ankylosis of joint Musculoskeletal 0.981 0.738 – 1.3 0.893 49 373 exclusion phecode
741.2 Stiffness of joint Musculoskeletal 1.01 0.901 – 1.13 0.891 362 2225 exclusion phecode
741.3 Difficulty in walking Musculoskeletal 0.951 0.886 – 1.02 0.162 964 4068 exclusion phecode
741.4 Joint effusions Musculoskeletal 1.03 0.961 – 1.11 0.389 983 4207 exclusion phecode
741.5 Hemarthrosis Musculoskeletal 1.26 0.878 – 1.81 0.211 46 189 exclusion phecode
741.6 Villonodular synovitis Musculoskeletal 0.858 0.502 – 1.47 0.577 22 113 exclusion phecode
742 Derangement of joint, non-traumatic Musculoskeletal 0.937 0.883 – 0.995 0.0334 1349 5821 exclusion phecode
742.1 Loose body in joint Musculoskeletal 1.01 0.703 – 1.45 0.952 35 227 exclusion phecode
742.2
Pathological, developmental or recurrent
Pathological, developmental or recurrent dislocation
 Musculoskeletal 1.04 0.793 – 1.38 0.758 60 393 exclusion phecode
742.8 Articular cartilage disorder Musculoskeletal 0.903 0.702 – 1.16 0.427 61 379 exclusion phecode
742.9 Other derangement of joint Musculoskeletal 0.934 0.879 – 0.994 0.0309 1273 5663 exclusion phecode
743
Osteoporosis, osteopenia and pathological
Osteoporosis, osteopenia and pathological fracture
 Musculoskeletal 0.989 0.943 – 1.04 0.636 2821 6655 exclusion phecode
743.1 Osteoporosis Musculoskeletal 1.01 0.94 – 1.08 0.808 1122 3538 exclusion phecode
743.11 Osteoporosis NOS Musculoskeletal 1 0.932 – 1.08 0.965 1103 3501 exclusion phecode
743.12 Senile osteoporosis Musculoskeletal 0.893 0.774 – 1.03 0.119 252 850 exclusion phecode
743.13 Other specified osteoporosis Musculoskeletal 0.976 0.798 – 1.19 0.816 120 521 exclusion phecode
743.2 Pathologic fracture Musculoskeletal 0.975 0.871 – 1.09 0.667 360 1770 exclusion phecode
743.21 Pathologic fracture of vertebrae Musculoskeletal 0.988 0.831 – 1.17 0.891 156 782 exclusion phecode
743.22 Pathologic fracture of femur Musculoskeletal 1.17 0.822 – 1.66 0.389 41 220 exclusion phecode
743.4 Stress fracture Musculoskeletal 0.943 0.799 – 1.11 0.484 170 847 exclusion phecode
743.9
Osteopenia or other disorder of bone and
Osteopenia or other disorder of bone and cartilage
 Musculoskeletal 0.987 0.939 – 1.04 0.621 2300 6345 exclusion phecode
745 Pain in joint Musculoskeletal 0.925 0.887 – 0.966 0.000342 6063 3607 exclusion phecode
747 Cardiac and circulatory congenital anomalies Congenital Anomalies 1.04 0.965 – 1.12 0.312 914 4487 exclusion phecode
747.1 Cardiac congenital anomalies Congenital Anomalies 1.05 0.974 – 1.14 0.194 776 3607 exclusion phecode
747.11 Cardiac shunt/ heart septal defect Congenital Anomalies 0.975 0.853 – 1.11 0.705 282 1284 exclusion phecode
747.12 Valvular heart disease/ heart chambers Congenital Anomalies 1.09 0.972 – 1.22 0.142 391 1587 exclusion phecode
747.13 Congenital anomalies of great vessels Congenital Anomalies 1.17 0.988 – 1.39 0.0689 175 850 exclusion phecode
747.2
Congenital anomalies of peripheral vascular
Congenital anomalies of peripheral vascular system
 Congenital Anomalies 1.01 0.851 – 1.2 0.9 155 956 exclusion phecode
748 Anomalies of respiratory system, congenital Congenital Anomalies 1 0.681 – 1.47 0.999 29 224 exclusion phecode
749 Congenital anomalies of face and neck Congenital Anomalies 1.02 0.84 – 1.24 0.834 114 972 exclusion phecode
749.1 Cleft palate Congenital Anomalies 0.952 0.414 – 2.19 0.908 6 122 exclusion phecode
749.2 Congenital anomalies of skull and face bones Congenital Anomalies 1.03 0.638 – 1.65 0.918 20 176 exclusion phecode
750 Digestive congenital anomalies Congenital Anomalies 0.922 0.813 – 1.04 0.201 275 1783 exclusion phecode
750.1 Upper gastrointestinal congenital anomalies Congenital Anomalies 0.97 0.763 – 1.23 0.8 70 682 exclusion phecode
750.11 Esophageal atresia/tracheoesophageal fistula Congenital Anomalies 0.75 0.516 – 1.09 0.132 30 231 exclusion phecode
750.13 Congenital anomalies of mouth/tongue Congenital Anomalies 0.8 0.49 – 1.3 0.37 15 147 exclusion phecode
750.14 Congenital anomalies of esophagus Congenital Anomalies 1.05 0.738 – 1.5 0.78 29 249 exclusion phecode
750.15 Congenital anomalies of stomach Congenital Anomalies 1.37 0.765 – 2.44 0.292 12 110 exclusion phecode
750.2 Lower gastrointestinal congenital anomalies Congenital Anomalies 0.942 0.813 – 1.09 0.428 204 1147 exclusion phecode
750.21 Congenital anomalies of intestine Congenital Anomalies 0.847 0.695 – 1.03 0.103 110 655 exclusion phecode
750.22
Congenital anomaly of gallbladder, bile ducts
Congenital anomaly of gallbladder, bile ducts, liver, pancreas
 Congenital Anomalies 0.955 0.764 – 1.19 0.684 97 468 exclusion phecode
751 Genitourinary congenital anomalies Congenital Anomalies 0.945 0.868 – 1.03 0.188 646 3888 exclusion phecode
751.1 Congenital anomalies of genital organs Congenital Anomalies 1 0.847 – 1.18 0.996 163 1092 exclusion phecode
751.11 Congenital anomalies of female genital organs Congenital Anomalies 0.887 0.727 – 1.08 0.237 110 726 exclusion phecode
751.12 Congenital anomalies of male genital organs Congenital Anomalies 1.16 0.807 – 1.67 0.421 37 312 exclusion phecode
751.2 Congenital anomalies of urinary system Congenital Anomalies 0.934 0.847 – 1.03 0.171 486 2743 exclusion phecode
751.21 Cystic kidney disease Congenital Anomalies 0.906 0.81 – 1.01 0.0837 377 1975 exclusion phecode
751.22 Other specified congenital anomalies of kidney Congenital Anomalies 0.964 0.771 – 1.2 0.745 84 584 exclusion phecode
751.3 Obstructive genitourinary defect Congenital Anomalies 1.07 0.76 – 1.5 0.704 35 335 exclusion phecode
752 Nervous system congenital anomalies Congenital Anomalies 0.94 0.83 – 1.06 0.332 275 2152 exclusion phecode
752.1 Neural tube defects Congenital Anomalies 0.95 0.827 – 1.09 0.471 222 1732 exclusion phecode
752.11 Spina bifida Congenital Anomalies 0.96 0.682 – 1.35 0.815 34 316 exclusion phecode
752.2
Other specified congenital anomalies of nervous
Other specified congenital anomalies of nervous system
 Congenital Anomalies 0.93 0.714 – 1.21 0.591 56 435 exclusion phecode
753 Congenital anomalies of the eye Congenital Anomalies 1.01 0.791 – 1.28 0.962 79 517 exclusion phecode
753.1 Congenital cataract and lens anomalies Congenital Anomalies 1.07 0.679 – 1.69 0.768 23 152 exclusion phecode
753.2 Congenital anomalies of posterior segment of eye Congenital Anomalies 1.08 0.669 – 1.73 0.762 22 142 exclusion phecode
754 Congenital musculoskeletal deformities of spine Congenital Anomalies 0.938 0.836 – 1.05 0.275 339 2345 exclusion phecode
754.1 Lumbosacral spondylolysis, congenital Congenital Anomalies 0.883 0.647 – 1.21 0.435 52 280 exclusion phecode
754.2 Spondylolisthesis, congenital Congenital Anomalies 0.959 0.807 – 1.14 0.636 148 1069 exclusion phecode
755 Congenital anomalies of limbs Congenital Anomalies 0.938 0.816 – 1.08 0.372 218 1518 exclusion phecode
755.1 Congenital deformities of feet Congenital Anomalies 0.992 0.815 – 1.21 0.939 113 775 exclusion phecode
755.4
Congenital anomalies of upper limb, including
Congenital anomalies of upper limb, including shoulder girdle
 Congenital Anomalies 0.748 0.443 – 1.26 0.278 18 140 exclusion phecode
755.6
Other congenital anomalies of lower limb
Other congenital anomalies of lower limb, including pelvic girdle
 Congenital Anomalies 0.876 0.709 – 1.08 0.219 88 579 exclusion phecode
755.61 Congenital hip dysplasia and deformity Congenital Anomalies 0.912 0.683 – 1.22 0.534 47 350 exclusion phecode
756 Other congenital musculoskeletal anomalies Congenital Anomalies 0.949 0.852 – 1.06 0.336 371 2554 exclusion phecode
756.1 Congenital anomalies of abdominal wall; diaphram Congenital Anomalies 0.851 0.482 – 1.5 0.577 16 116 exclusion phecode
756.2
Pectus and other congenital anomalies of
Pectus and other congenital anomalies of ribs/sternum
 Congenital Anomalies 1.26 0.763 – 2.09 0.365 19 103 exclusion phecode
756.3
Congenital anomalies of muscle, tendon, fascia
Congenital anomalies of muscle, tendon, fascia, and connective tissue
 Congenital Anomalies 0.942 0.765 – 1.16 0.57 94 578 exclusion phecode
756.5 Congenital osteodystrophies Congenital Anomalies 0.966 0.854 – 1.09 0.584 274 1977 exclusion phecode
757 Congenital anomalies of the integument Congenital Anomalies 1.11 0.91 – 1.35 0.307 106 848 exclusion phecode
758 Chromosomal anomalies and genetic disorders Congenital Anomalies 0.957 0.732 – 1.25 0.745 69 396 exclusion phecode
758.1 Chromosomal anomalies Congenital Anomalies 0.908 0.657 – 1.25 0.558 48 298 exclusion phecode
759 Other and unspecified congenital anomalies Congenital Anomalies 1.06 0.897 – 1.26 0.477 158 1067 exclusion phecode
759.1 Anomalies of endocrine glands, congenital Congenital Anomalies 1.02 0.627 – 1.66 0.935 17 150 exclusion phecode
760 Back pain Symptoms 0.958 0.919 – 0.998 0.0383 5007 4666 exclusion phecode
761 Cervicalgia Symptoms 0.966 0.921 – 1.01 0.164 2209 7376 exclusion phecode
763
Thoracic or lumbosacral neuritis or
Thoracic or lumbosacral neuritis or radiculitis, unspecified
 Symptoms 0.97 0.912 – 1.03 0.337 1244 5925 exclusion phecode
764 Sciatica Symptoms 1.01 0.947 – 1.07 0.814 1268 5947 exclusion phecode
765 Cervical radiculitis Symptoms 0.945 0.865 – 1.03 0.204 588 3387 exclusion phecode
766 Neuralgia, neuritis, and radiculitis NOS Symptoms 0.951 0.9 – 1 0.0703 1611 6710 exclusion phecode
767 Cervicocranial/Cervicobrachial syndrome Symptoms 1.08 0.806 – 1.45 0.602 47 255 exclusion phecode
769 Nonallopathic lesions NEC Symptoms 0.937 0.841 – 1.04 0.232 395 2398 exclusion phecode
770 Myalgia and myositis unspecified Symptoms 0.972 0.921 – 1.03 0.306 1692 6734 exclusion phecode
771 Musculoskeletal symptoms referable to limbs Symptoms 0.954 0.902 – 1.01 0.0987 1606 5965 exclusion phecode
771.1 Swelling of limb Symptoms 0.964 0.917 – 1.01 0.151 2219 6003 exclusion phecode
771.2 Cramp of limb Symptoms 0.929 0.837 – 1.03 0.169 430 2058 exclusion phecode
772 Symptoms of the muscles Symptoms 0.944 0.871 – 1.02 0.159 718 3865 exclusion phecode
772.1 Muscular wasting and disuse atrophy Symptoms 1.19 0.975 – 1.46 0.0871 126 756 exclusion phecode
772.2 Spasm of muscle Symptoms 0.973 0.899 – 1.05 0.49 740 4223 exclusion phecode
772.3 Muscle weakness Symptoms 1.01 0.942 – 1.08 0.836 1081 5232 exclusion phecode
772.4 Rhabdomyolysis Symptoms 1.07 0.816 – 1.39 0.641 66 314 exclusion phecode
772.6 Facial weakness Symptoms 0.968 0.828 – 1.13 0.682 196 939 exclusion phecode
780 Hypothermia/Chills Symptoms 1.1 0.944 – 1.28 0.225 200 1050 exclusion phecode
781
Symptoms involving nervous and musculoskeletal
Symptoms involving nervous and musculoskeletal systems
 Symptoms 0.971 0.91 – 1.04 0.373 1127 5294 exclusion phecode
781.1 Loss of height Symptoms 0.952 0.716 – 1.27 0.738 61 298 exclusion phecode
781.2 Abnormal posture Symptoms 0.955 0.61 – 1.49 0.84 24 121 exclusion phecode
782.3 Edema Symptoms 0.999 0.952 – 1.05 0.953 2356 6474 exclusion phecode
782.6 Pallor and flushing Symptoms 0.979 0.86 – 1.11 0.744 265 1624 exclusion phecode
783 Fever of unknown origin Symptoms 1.05 1 – 1.11 0.037 2137 7433 exclusion phecode
783.1 Postprocedural fever Symptoms 0.962 0.762 – 1.22 0.749 85 523 exclusion phecode
785 Abdominal pain Symptoms 0.958 0.919 – 0.998 0.039 5240 4431 exclusion phecode
788 Syncope and collapse Symptoms 1.04 0.982 – 1.1 0.183 1525 6931 exclusion phecode
789 Nausea and vomiting Symptoms 1.03 0.985 – 1.08 0.195 3148 6487 exclusion phecode
789.1 Persistent vomiting Symptoms 1.01 0.885 – 1.15 0.921 271 1389 exclusion phecode
790 Nonspecific findings on examination of blood Symptoms 1.05 0.984 – 1.13 0.135 1067 3880 exclusion phecode
790.1 Elevated sedimentation rate Symptoms 1.08 0.865 – 1.36 0.489 94 413 exclusion phecode
790.6 Other abnormal blood chemistry Symptoms 1.02 0.975 – 1.06 0.404 3143 6106 exclusion phecode
790.8 Elevated C-reactive protein (CRP) Symptoms 0.926 0.758 – 1.13 0.45 112 499 exclusion phecode
790.9 Abnormal arterial blood gases Symptoms 0.989 0.761 – 1.28 0.933 62 263 exclusion phecode
791 Gangrene Symptoms 1.11 0.923 – 1.33 0.269 153 748 exclusion phecode
792
Abnormal Papanicolaou smear of cervix and
Abnormal Papanicolaou smear of cervix and cervical HPV
 Genitourinary 0.933 0.861 – 1.01 0.097 815 2438 exclusion phecode
792.1
Papanicolaou smear of cervix or vagina with
Papanicolaou smear of cervix or vagina with atypical squamous cells
 Genitourinary 0.991 0.878 – 1.12 0.883 344 1547 exclusion phecode
794
Abnormal results of other function studies
Abnormal results of other function studies (bladder, pancreas, placenta, spleen, etc)
 Symptoms 0.961 0.783 – 1.18 0.707 106 1006 exclusion phecode
795
Other and nonspecific abnormal cytological
Other and nonspecific abnormal cytological, histological and immunological findings
 Symptoms 1.02 0.936 – 1.11 0.657 606 3797 exclusion phecode
795.8 Abnormal tumor markers Symptoms 0.928 0.841 – 1.02 0.135 458 3468 exclusion phecode
795.81 Elevated carcinoembryonic antigen [CEA] Symptoms 1.06 0.627 – 1.8 0.82 15 131 exclusion phecode
795.82 Elevated cancer antigen 125 [CA 125] Symptoms 0.713 0.504 – 1.01 0.0559 37 339 exclusion phecode
796 Elevated prostate specific antigen [PSA] Genitourinary 0.879 0.8 – 0.965 0.00709 616 2005 exclusion phecode
797 Shock Symptoms 1.05 0.929 – 1.19 0.426 301 1358 exclusion phecode
797.1 Cardiogenic shock Symptoms 1.05 0.872 – 1.26 0.606 156 599 exclusion phecode
798 Malaise and fatigue Symptoms 0.989 0.949 – 1.03 0.594 4173 5496 exclusion phecode
798.1 Chronic fatigue syndrome Symptoms 0.964 0.887 – 1.05 0.387 700 2949 exclusion phecode
800 Fracture of lower limb Injuries & Poisonings 0.95 0.877 – 1.03 0.207 694 4223 exclusion phecode
800.1 Fracture of neck of femur Injuries & Poisonings 0.951 0.814 – 1.11 0.524 178 962 exclusion phecode
800.2 Fracture of unspecified part of femur Injuries & Poisonings 0.985 0.847 – 1.15 0.848 196 1206 exclusion phecode
800.3 Fracture of tibia and fibula Injuries & Poisonings 0.931 0.815 – 1.06 0.297 252 1568 exclusion phecode
800.4 Fracture of patella Injuries & Poisonings 0.926 0.759 – 1.13 0.449 113 622 exclusion phecode
801 Fracture of ankle and foot Injuries & Poisonings 0.939 0.873 – 1.01 0.0922 861 4449 exclusion phecode
801.1 Fracture of foot Injuries & Poisonings 0.9 0.805 – 1.01 0.0645 339 2087 exclusion phecode
802 Fracture of pelvis Injuries & Poisonings 0.973 0.792 – 1.2 0.794 102 648 exclusion phecode
803 Fracture of upper limb Injuries & Poisonings 0.877 0.804 – 0.955 0.00263 594 3705 exclusion phecode
803.1 Fracture of humerus Injuries & Poisonings 0.888 0.767 – 1.03 0.111 213 1283 exclusion phecode
803.2 Fracture of radius and ulna Injuries & Poisonings 0.877 0.781 – 0.984 0.0253 334 2042 exclusion phecode
803.21 Colles' fracture Injuries & Poisonings 0.729 0.584 – 0.91 0.00527 87 520 exclusion phecode
803.3 Fracture of clavicle or scapula Injuries & Poisonings 0.832 0.69 – 1 0.0556 134 903 exclusion phecode
804 Fracture of hand or wrist Injuries & Poisonings 0.962 0.875 – 1.06 0.417 516 3008 exclusion phecode
805
Fracture of vertebral column without mention of
Fracture of vertebral column without mention of spinal cord injury
 Injuries & Poisonings 1.03 0.922 – 1.14 0.631 398 2379 exclusion phecode
807 Fracture of ribs Injuries & Poisonings 1.03 0.903 – 1.17 0.667 262 1352 exclusion phecode
809 Fracture of unspecified bones Injuries & Poisonings 0.949 0.882 – 1.02 0.158 839 5265 exclusion phecode
816 Cerebral laceration and contusion Injuries & Poisonings 0.932 0.561 – 1.55 0.786 17 109 exclusion phecode
817 Concussion Injuries & Poisonings 1.03 0.916 – 1.16 0.626 353 2066 exclusion phecode
818 Intracranial hemorrhage (injury) Injuries & Poisonings 0.929 0.768 – 1.12 0.445 119 728 exclusion phecode
818.1 Subdural hemorrhage (injury) Injuries & Poisonings 0.758 0.525 – 1.09 0.139 32 199 exclusion phecode
818.2 Subarachnoid hemorrhage (injury) Injuries & Poisonings 1.22 0.833 – 1.8 0.303 32 244 exclusion phecode
819
Skull and face fracture and other intercranial
Skull and face fracture and other intercranial injury
 Injuries & Poisonings 1.01 0.934 – 1.1 0.737 671 4482 exclusion phecode
830 Dislocation Injuries & Poisonings 0.955 0.896 – 1.02 0.159 1115 6642 exclusion phecode
835 Internal derangement of knee Injuries & Poisonings 0.982 0.906 – 1.06 0.661 711 4300 exclusion phecode
836 Traumatic arthropathy Injuries & Poisonings 0.923 0.771 – 1.11 0.386 148 908 exclusion phecode
840 Sprains and strains Injuries & Poisonings 0.941 0.898 – 0.985 0.00898 2569 6735 exclusion phecode
840.1 Muscle/tendon sprain Injuries & Poisonings 0.913 0.783 – 1.07 0.247 199 985 exclusion phecode
840.2 Rotator cuff (capsule) sprain Injuries & Poisonings 0.867 0.793 – 0.948 0.00182 574 3052 exclusion phecode
840.3 Joint/ligament sprain Injuries & Poisonings 0.914 0.849 – 0.983 0.0161 858 4465 exclusion phecode
841 Sprains and strains of back and neck Injuries & Poisonings 0.862 0.792 – 0.939 0.000672 647 3056 exclusion phecode
842 Other sprains and strains Injuries & Poisonings 0.963 0.874 – 1.06 0.449 499 2574 exclusion phecode
850 Hemorrhage or hematoma complicating a procedure Injuries & Poisonings 1.04 0.959 – 1.14 0.32 648 3586 exclusion phecode
851
Complications of transplants and reattached
Complications of transplants and reattached limbs
 Injuries & Poisonings 1.05 0.986 – 1.13 0.122 1087 4834 exclusion phecode
853 Complication of colostomy or enterostomy Injuries & Poisonings 1.14 0.94 – 1.37 0.186 132 681 exclusion phecode
854
Complications of cardiac/vascular device
Complications of cardiac/vascular device, implant, and graft
 Injuries & Poisonings 1.11 1.03 – 1.2 0.00591 895 3683 exclusion phecode
855
Complication of nervous system device, implant
Complication of nervous system device, implant, and graft
 Injuries & Poisonings 1.47 1.06 – 2.04 0.0221 47 417 exclusion phecode
856
Vascular complications of surgery and medical
Vascular complications of surgery and medical procedures
 Injuries & Poisonings 1.08 0.882 – 1.34 0.441 121 513 exclusion phecode
857
Mechanical complication of unspecified
Mechanical complication of unspecified genitourinary device, implant, and graft
 Injuries & Poisonings 1.05 0.94 – 1.18 0.378 359 2342 exclusion phecode
858 Complication of internal orthopedic device Injuries & Poisonings 0.993 0.9 – 1.1 0.896 442 3458 exclusion phecode
859
Complication due to other implant and internal
Complication due to other implant and internal device
 Injuries & Poisonings 1.08 0.989 – 1.19 0.0849 532 3638 exclusion phecode
860 Bone marrow or stem cell transplant Neoplasms 0.914 0.694 – 1.2 0.522 68 403 exclusion phecode
870 Open wounds of head; neck; and trunk Injuries & Poisonings 0.994 0.936 – 1.06 0.844 1258 6694 exclusion phecode
870.1 Open wound or laceration of eye or eyelid Injuries & Poisonings 1.06 0.81 – 1.38 0.679 64 432 exclusion phecode
870.2 Open wound of ear Injuries & Poisonings 1.11 0.797 – 1.53 0.548 45 251 exclusion phecode
870.3 Other open wound of head and face Injuries & Poisonings 0.885 0.796 – 0.984 0.0244 385 2549 exclusion phecode
870.4 Open wound of nose and sinus Injuries & Poisonings 0.878 0.637 – 1.21 0.428 41 368 exclusion phecode
870.5 Open wound of lip and mouth Injuries & Poisonings 0.932 0.712 – 1.22 0.606 58 482 exclusion phecode
870.6 Open wound of neck Injuries & Poisonings 0.773 0.54 – 1.11 0.159 33 362 exclusion phecode
870.8 Open wound of genital organs Injuries & Poisonings 1.08 0.744 – 1.57 0.683 28 267 exclusion phecode
871 Open wounds of extremities Injuries & Poisonings 0.98 0.922 – 1.04 0.513 1288 6257 exclusion phecode
871.1 Open wound of hand except finger(s) Injuries & Poisonings 0.976 0.833 – 1.14 0.764 190 1106 exclusion phecode
871.2 Open wound of finger(s) Injuries & Poisonings 0.931 0.833 – 1.04 0.212 369 2169 exclusion phecode
871.3 Open wound of foot except toe(s) alone Injuries & Poisonings 1.01 0.875 – 1.16 0.916 253 1255 exclusion phecode
871.4 Open wound of toe(s) Injuries & Poisonings 1.11 0.93 – 1.32 0.255 171 860 exclusion phecode
872 Traumatic amputation Injuries & Poisonings 1.06 0.922 – 1.23 0.4 230 1228 exclusion phecode
874 Complication of amputation stump Injuries & Poisonings 0.971 0.765 – 1.23 0.809 83 384 exclusion phecode
875 Non-healing surgical wound Injuries & Poisonings 1.02 0.855 – 1.21 0.856 164 1017 exclusion phecode
876
Posttraumatic wound infection not elsewhere
Posttraumatic wound infection not elsewhere classified
 Injuries & Poisonings 1.08 0.952 – 1.22 0.242 287 1574 exclusion phecode
907 Injuries to the nervous system Injuries & Poisonings 1.04 0.905 – 1.2 0.581 219 1928 exclusion phecode
910 Superficial injury, infected Injuries & Poisonings 1.2 0.903 – 1.6 0.206 61 271 exclusion phecode
911 Blister Injuries & Poisonings 0.948 0.806 – 1.11 0.519 170 927 exclusion phecode
912 Insect bite Injuries & Poisonings 0.842 0.728 – 0.975 0.0214 205 1157 exclusion phecode
913 Toxic effect of venom Injuries & Poisonings 0.805 0.67 – 0.968 0.0213 144 743 exclusion phecode
916 Contusion Injuries & Poisonings 0.978 0.928 – 1.03 0.415 1729 7132 exclusion phecode
930 Allergic reaction to food Injuries & Poisonings 0.915 0.802 – 1.04 0.186 279 1161 exclusion phecode
931
Contact dermatitis and other eczema due to
Contact dermatitis and other eczema due to plants [except food]
 Dermatologic 0.785 0.68 – 0.905 0.000879 239 1217 exclusion phecode
938 Dermatitis due to solar radiation Dermatologic 0.935 0.887 – 0.986 0.0132 2085 4391 exclusion phecode
938.1 Acute dermatitis due to solar radiation Dermatologic 0.854 0.666 – 1.1 0.216 80 329 exclusion phecode
938.2 Chronic dermatitis due to solar radiation Dermatologic 0.936 0.887 – 0.987 0.0156 2009 4330 exclusion phecode
939
Atopic/contact dermatitis due to other or
Atopic/contact dermatitis due to other or unspecified
 Dermatologic 0.958 0.912 – 1.01 0.0874 2549 4785 exclusion phecode
939.1 Contact and allergic dermatitis of eyelid Dermatologic 1.04 0.722 – 1.51 0.82 35 159 exclusion phecode
941 Adverse reaction to serum or vaccine Injuries & Poisonings 1.15 0.89 – 1.49 0.284 75 324 exclusion phecode
942 Infusion and transfusion reaction Injuries & Poisonings 1.16 0.934 – 1.45 0.176 114 425 exclusion phecode
946 Anaphylactic shock NOS Injuries & Poisonings 0.86 0.732 – 1.01 0.0646 195 874 exclusion phecode
947 Urticaria Dermatologic 1.01 0.902 – 1.13 0.896 401 1826 exclusion phecode
949 Allergies, other Injuries & Poisonings 0.959 0.912 – 1.01 0.1 2455 4784 exclusion phecode
952
Spinal cord injury without evidence of spinal
Spinal cord injury without evidence of spinal bone injury
 Injuries & Poisonings 1.07 0.873 – 1.31 0.52 114 973 exclusion phecode
957 Injury to other and unspecified nerves Injuries & Poisonings 0.762 0.504 – 1.15 0.199 25 242 exclusion phecode
958
Certain early complications of trauma or
Certain early complications of trauma or procedure
 Injuries & Poisonings 1.06 0.951 – 1.19 0.275 369 2396 exclusion phecode
958.1 Postoperative shock Injuries & Poisonings 1.18 0.907 – 1.54 0.218 74 339 exclusion phecode
958.2 Traumatic and surgical subcutaneous emphysema Injuries & Poisonings 1.11 0.74 – 1.66 0.613 28 239 exclusion phecode
960 Poisoning by antibiotics Injuries & Poisonings 0.977 0.905 – 1.06 0.559 776 3940 exclusion phecode
960.1
Adverse effects of antibacterials (not
Adverse effects of antibacterials (not penicillins)
 Injuries & Poisonings 0.967 0.808 – 1.16 0.718 143 692 exclusion phecode
960.2 Allergy/adverse effect of penicillin Injuries & Poisonings 1 0.913 – 1.1 0.946 490 2760 exclusion phecode
961 Poisoning by other anti-infectives Injuries & Poisonings 0.979 0.837 – 1.15 0.792 196 913 exclusion phecode
961.1 Poisoning/allergy of sulfonamides Injuries & Poisonings 0.981 0.874 – 1.1 0.746 320 1810 exclusion phecode
962 Poisoning by hormones and synthetic substitutes Injuries & Poisonings 1.05 0.939 – 1.18 0.379 358 1711 exclusion phecode
962.1
Adrenal cortical steroids causing adverse
Adrenal cortical steroids causing adverse effects in therapeutic use
 Injuries & Poisonings 1.04 0.879 – 1.23 0.65 178 770 exclusion phecode
962.2
Insulins and antidiabetic agents causing
Insulins and antidiabetic agents causing adverse effects in therapeutic use
 Injuries & Poisonings 1.05 0.748 – 1.48 0.774 41 226 exclusion phecode
962.3
Hormones and synthetic substitutes causing
Hormones and synthetic substitutes causing adverse effects in therapeutic use
 Injuries & Poisonings 1.08 0.927 – 1.25 0.327 194 1032 exclusion phecode
963 Poisoning by primarily systemic agents Injuries & Poisonings 1.02 0.937 – 1.1 0.712 728 4057 exclusion phecode
963.1
Antineoplastic and immunosuppressive drugs
Antineoplastic and immunosuppressive drugs causing adverse effects
 Injuries & Poisonings 1.04 0.958 – 1.13 0.36 702 3964 exclusion phecode
964
Poisoning by agents primarily affecting blood
Poisoning by agents primarily affecting blood constituents
 Injuries & Poisonings 1 0.898 – 1.12 0.942 379 1547 exclusion phecode
964.1 Anticoagulants causing adverse effects Injuries & Poisonings 0.981 0.875 – 1.1 0.737 362 1482 exclusion phecode
965
Poisoning by analgesics, antipyretics, and
Poisoning by analgesics, antipyretics, and antirheumatics
 Injuries & Poisonings 1.09 0.963 – 1.24 0.17 297 1465 exclusion phecode
965.1
Opiates and related narcotics causing adverse
Opiates and related narcotics causing adverse effects in therapeutic use
 Injuries & Poisonings 0.982 0.889 – 1.08 0.722 454 2386 exclusion phecode
965.3
Salicylates causing adverse effects in
Salicylates causing adverse effects in therapeutic use
 Injuries & Poisonings 0.948 0.665 – 1.35 0.766 33 207 exclusion phecode
966
Poisoning by anticonvulsants and
Poisoning by anticonvulsants and anti-Parkinsonism drugs
 Injuries & Poisonings 0.758 0.529 – 1.09 0.131 29 187 exclusion phecode
967
Adverse effects of sedatives or other central
Adverse effects of sedatives or other central nervous system depressants and anesthetics
 Injuries & Poisonings 0.952 0.848 – 1.07 0.399 328 2129 exclusion phecode
969 Poisoning by psychotropic agents Injuries & Poisonings 0.996 0.799 – 1.24 0.971 110 471 exclusion phecode
971
Poisoning by drugs primarily affecting the
Poisoning by drugs primarily affecting the autonomic nervous system
 Injuries & Poisonings 0.799 0.506 – 1.26 0.336 37 162 exclusion phecode
972
Poisoning by agents primarily affecting the
Poisoning by agents primarily affecting the cardiovascular system
 Injuries & Poisonings 0.998 0.84 – 1.19 0.984 157 615 exclusion phecode
972.1
Cardiac rhythm regulators causing adverse
Cardiac rhythm regulators causing adverse effects in therapeutic use
 Injuries & Poisonings 1.02 0.738 – 1.4 0.92 46 166 exclusion phecode
972.6 Antihypertensive agents causing adverse effects Injuries & Poisonings 0.949 0.722 – 1.25 0.706 67 219 exclusion phecode
974
Poisoning by water, mineral, and uric acid
Poisoning by water, mineral, and uric acid metabolism drugs
 Injuries & Poisonings 1.06 0.801 – 1.41 0.678 68 275 exclusion phecode
975
Poisoning by agents primarily acting on the
Poisoning by agents primarily acting on the smooth and skeletal muscles and respiratory system
 Injuries & Poisonings 0.696 0.467 – 1.04 0.0749 32 135 exclusion phecode
976
Poisoning by agents primarily affecting skin &
Poisoning by agents primarily affecting skin & mucous membrane, ophthalmological, otorhinolaryngological, & dental drugs
 Injuries & Poisonings 1.22 0.821 – 1.81 0.328 30 138 exclusion phecode
977 Personal history of allergy to medicinal agents Injuries & Poisonings 1.02 0.931 – 1.11 0.699 615 2916 exclusion phecode
979 Adverse drug events and drug allergies Injuries & Poisonings 0.992 0.932 – 1.06 0.794 1234 5603 exclusion phecode
980
Encounter for long-term (current) use of
Encounter for long-term (current) use of antibiotics
 Infectious Diseases 1.02 0.918 – 1.13 0.753 422 3000 exclusion phecode
985 Toxic effect of other metals Injuries & Poisonings 1.49 0.886 – 2.5 0.133 19 129 exclusion phecode
989
Toxic effect of other substances, chiefly
Toxic effect of other substances, chiefly nonmedicinal as to source
 Injuries & Poisonings 0.841 0.625 – 1.13 0.253 48 333 exclusion phecode
990 Effects radiation NOS Injuries & Poisonings 0.991 0.919 – 1.07 0.826 755 5841 exclusion phecode
994 Sepsis and SIRS Injuries & Poisonings 1.06 0.985 – 1.14 0.124 883 4532 exclusion phecode
994.1 Systemic inflammatory response syndrome (SIRS) Injuries & Poisonings 0.959 0.787 – 1.17 0.675 120 633 exclusion phecode
994.2 Sepsis Injuries & Poisonings 1.06 0.982 – 1.14 0.141 849 4334 exclusion phecode
994.21 Septic shock Injuries & Poisonings 1.04 0.92 – 1.18 0.52 295 1278 exclusion phecode
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