Departments of Anesthesiology and Biostatistics | University of Michigan

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Scores Direct LDL cholesterol (IRNT) Michigan Genomics Initiative Freeze 3 (MGI) PheWAS analysis

Direct LDL cholesterol (IRNT) — Michigan Genomics Initiative Freeze 3 (MGI) PRS PheWAS

PRS model
PRS ID exprsweb-ldl-30780-irnt-pt-mgi-freeze3-20211120Legacy PTC+T (DS)UK Biobank GWAS

Evaluation cohort: Michigan Genomics Initiative Freeze 3 (MGI).

This page pairs the PheWAS plot with the full sortable table for the all-subject and exclusion scans.

Read the all-subject and exclusion scans separately. The combined view is only a browsing aid, and the selected-phecode panel below is only meaningful when the same phecode exists in both scans.

ExPRS exclusion definition

Exclusion cohort: normal-range subset (0.01-100).

For this ExPRS, the exclusion sensitivity scan keeps only the study's normal-range subset for Direct LDL cholesterol (IRNT) (0.01-100) before rerunning the PheWAS. This is an exposure-based sensitivity analysis rather than a diagnosis-based exclusion.

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Signal overview

The plot gives a quick view of the currently visible associations. Click a point to pin its details, inspect that phecode across scans when both rows exist, or open the matching phecode detail page.

147 rows visible 17 categories
Phecode Description Category OR 95% CI P value Cases Controls Analysis Link
008 Intestinal infection Infectious Diseases 0.982 0.946 – 1.02 0.342 3004 29292 all phecode
008.5 Bacterial enteritis Infectious Diseases 0.993 0.938 – 1.05 0.816 1322 13162 all phecode
008.52 Intestinal infection due to C. difficile Infectious Diseases 1.02 0.954 – 1.08 0.612 1046 10455 all phecode
008.6 Viral Enteritis Infectious Diseases 0.986 0.916 – 1.06 0.715 770 7676 all phecode
010 Tuberculosis Infectious Diseases 1 0.881 – 1.14 0.965 244 2425 all phecode
031 Diseases due to other mycobacteria Infectious Diseases 0.903 0.728 – 1.12 0.353 86 855 all phecode
038 Septicemia Infectious Diseases 1.02 0.981 – 1.06 0.305 2582 24779 all phecode
038.1 Gram negative septicemia Infectious Diseases 1 0.918 – 1.09 0.984 568 5629 all phecode
038.2 Gram positive septicemia Infectious Diseases 0.985 0.861 – 1.13 0.826 235 2350 all phecode
038.3 Bacteremia Infectious Diseases 1.01 0.951 – 1.07 0.752 1210 12079 all phecode
041 Bacterial infection NOS Infectious Diseases 1 0.973 – 1.03 0.95 5750 38799 all phecode
041.1 Staphylococcus infections Infectious Diseases 0.958 0.912 – 1.01 0.0946 1707 16977 all phecode
041.11 Methicillin sensitive Staphylococcus aureus Infectious Diseases 0.948 0.886 – 1.01 0.125 920 9192 all phecode
041.12 Methicillin resistant Staphylococcus aureus Infectious Diseases 0.962 0.894 – 1.04 0.302 783 7812 all phecode
041.2 Streptococcus infection Infectious Diseases 0.976 0.928 – 1.03 0.351 1632 16287 all phecode
041.21 Rheumatic fever / chorea Infectious Diseases 0.993 0.875 – 1.13 0.916 257 2554 all phecode
041.4 E. coli Infectious Diseases 1.04 0.978 – 1.1 0.211 1175 11680 all phecode
041.8 H. pylori Infectious Diseases 0.998 0.877 – 1.14 0.973 257 2521 all phecode
041.9 Infection with drug-resistant microorganisms Infectious Diseases 1.06 0.955 – 1.18 0.275 387 3864 all phecode
053 Herpes zoster Infectious Diseases 0.996 0.946 – 1.05 0.893 1560 15184 all phecode
053.1 Herpes zoster with nervous system complications Infectious Diseases 0.897 0.779 – 1.03 0.129 220 2169 all phecode
054 Herpes simplex Infectious Diseases 0.994 0.944 – 1.05 0.814 1593 15600 all phecode
070 Viral hepatitis Infectious Diseases 0.976 0.909 – 1.05 0.503 829 8280 all phecode
070.1 Viral hepatitis A Infectious Diseases 0.971 0.777 – 1.21 0.792 87 860 all phecode
070.2 Viral hepatitis B Infectious Diseases 0.933 0.813 – 1.07 0.32 215 2138 all phecode
070.3 Viral hepatitis C Infectious Diseases 0.958 0.877 – 1.05 0.349 528 5280 all phecode
070.4 Chronic hepatitis Infectious Diseases 1.04 0.898 – 1.21 0.584 197 1964 all phecode
070.9 Hepatitis NOS Infectious Diseases 0.998 0.939 – 1.06 0.956 1145 11381 all phecode
071 Human immunodeficiency virus [HIV] disease Infectious Diseases 1.22 1.02 – 1.45 0.0279 145 1450 all phecode
071.1 HIV infection, symptomatic Infectious Diseases 1.34 1.09 – 1.63 0.00461 117 1163 all phecode
078 Viral warts & HPV Infectious Diseases 1 0.965 – 1.04 0.987 3434 29624 all phecode
079 Viral infection Infectious Diseases 1.02 0.997 – 1.05 0.0857 6664 35342 all phecode
079.1 Varicella infection Infectious Diseases 1.01 0.976 – 1.04 0.564 3793 31251 all phecode
079.2 Infectious mononucleosis Infectious Diseases 1.11 0.977 – 1.26 0.109 283 2723 all phecode
079.9 Viremia, NOS Infectious Diseases 1.04 0.963 – 1.11 0.345 838 8253 all phecode
080 Postoperative infection Infectious Diseases 0.979 0.941 – 1.02 0.309 2619 26065 all phecode
081
Infection/inflammation of internal prosthetic
Infection/inflammation of internal prosthetic device; implant; and graft
 Infectious Diseases 0.969 0.92 – 1.02 0.239 1589 15884 all phecode
090
Sexually transmitted infections (not HIV or
Sexually transmitted infections (not HIV or hepatitis)
 Infectious Diseases 1.09 1.02 – 1.16 0.0129 965 9630 all phecode
110 Dermatophytosis / Dermatomycosis Infectious Diseases 0.98 0.946 – 1.01 0.254 3544 30054 all phecode
110.1 Dermatophytosis Infectious Diseases 0.977 0.942 – 1.01 0.228 3241 27244 all phecode
110.11 Dermatophytosis of nail Infectious Diseases 0.984 0.939 – 1.03 0.498 2044 16765 all phecode
110.12 Althete's foot Infectious Diseases 1 0.936 – 1.08 0.909 899 8043 all phecode
110.13 Dermatophytosis of the body Infectious Diseases 1 0.931 – 1.08 0.958 790 7827 all phecode
110.2 Dermatomycoses Infectious Diseases 0.967 0.873 – 1.07 0.525 398 3971 all phecode
112 Candidiasis Infectious Diseases 0.994 0.96 – 1.03 0.732 3685 30495 all phecode
112.3 Candidiasis of skin and nails Infectious Diseases 1.01 0.93 – 1.09 0.88 682 6732 all phecode
117 Mycoses Infectious Diseases 0.989 0.909 – 1.07 0.788 608 6069 all phecode
117.1 Histoplasmosis Infectious Diseases 0.953 0.758 – 1.2 0.677 81 801 all phecode
117.4 Aspergillosis Infectious Diseases 1.11 0.934 – 1.33 0.233 140 1387 all phecode
130 Spirochetal infection Infectious Diseases 0.987 0.844 – 1.15 0.87 168 1677 all phecode
130.1 Lyme disease Infectious Diseases 1.04 0.864 – 1.25 0.687 116 1160 all phecode
131 Protozoan infection Infectious Diseases 0.95 0.735 – 1.23 0.695 61 610 all phecode
132 Infestation (lice, mites) Infectious Diseases 0.874 0.756 – 1.01 0.0686 195 1948 all phecode
134 Helminthiases Infectious Diseases 0.92 0.739 – 1.14 0.452 83 812 all phecode
134.1 Intestinal helminthiases Infectious Diseases 0.896 0.683 – 1.18 0.429 53 513 all phecode
136 Other infectious and parasitic diseases Infectious Diseases 0.993 0.958 – 1.03 0.719 3279 32486 all phecode
145 Cancer of mouth Neoplasms 0.948 0.899 – 1 0.049 1481 14725 all phecode
145.1 Cancer of lip Neoplasms 0.784 0.625 – 0.985 0.0364 76 750 all phecode
145.2 Cancer of tongue Neoplasms 0.926 0.855 – 1 0.0576 645 6430 all phecode
145.3 Cancer of major salivary glands Neoplasms 1.01 0.907 – 1.13 0.832 361 3597 all phecode
145.4 Cancer of the gums Neoplasms 0.887 0.758 – 1.04 0.134 166 1632 all phecode
145.5 Cancer of the mouth floor Neoplasms 0.963 0.836 – 1.11 0.595 206 2048 all phecode
149 Cancer of larynx, pharynx, nasal cavities Neoplasms 0.956 0.904 – 1.01 0.118 1290 12873 all phecode
149.1 Cancer of oropharynx Neoplasms 1.01 0.905 – 1.12 0.884 350 3499 all phecode
149.2 Cancer of nasopharynx Neoplasms 0.879 0.723 – 1.07 0.197 100 1000 all phecode
149.3 Cancer of hypopharynx Neoplasms 1.18 0.941 – 1.48 0.151 82 819 all phecode
149.4 Cancer of larynx Neoplasms 0.979 0.882 – 1.09 0.695 386 3857 all phecode
149.5
Hx of malignant neoplasm of oral cavity and
Hx of malignant neoplasm of oral cavity and pharynx
 Neoplasms 0.893 0.82 – 0.974 0.0103 552 5505 all phecode
149.9 Cancer of of nasal cavities Neoplasms 1.01 0.888 – 1.15 0.854 240 2398 all phecode
150 Cancer of esophagus Neoplasms 1.06 0.956 – 1.17 0.287 433 4315 all phecode
151 Cancer of stomach Neoplasms 1.06 0.967 – 1.17 0.209 498 4962 all phecode
153 Colorectal cancer Neoplasms 1.03 0.975 – 1.09 0.294 1458 14383 all phecode
153.2 Colon cancer Neoplasms 1.04 0.978 – 1.11 0.207 1160 11472 all phecode
153.3
Malignant neoplasm of rectum, rectosigmoid
Malignant neoplasm of rectum, rectosigmoid junction, and anus
 Neoplasms 1.03 0.955 – 1.11 0.458 815 8093 all phecode
155 Cancer of liver and intrahepatic bile duct Neoplasms 1.03 0.941 – 1.13 0.492 511 5097 all phecode
155.1 Malignant neoplasm of liver, primary Neoplasms 1.07 0.95 – 1.2 0.277 344 3433 all phecode
157 Pancreatic cancer Neoplasms 0.955 0.871 – 1.05 0.32 503 5005 all phecode
158
Neoplasm of unspecified nature of digestive
Neoplasm of unspecified nature of digestive system
 Neoplasms 0.953 0.905 – 1 0.0624 1623 15759 all phecode
159
Malignant neoplasm of other and ill-defined
Malignant neoplasm of other and ill-defined sites within the digestive organs and peritoneum
 Neoplasms 1.01 0.966 – 1.06 0.583 1818 17869 all phecode
159.2
Malignant neoplasm of small intestine
Malignant neoplasm of small intestine, including duodenum
 Neoplasms 1.18 1.03 – 1.35 0.0193 221 2206 all phecode
159.3
Malignant neoplasm of gallbladder and
Malignant neoplasm of gallbladder and extrahepatic bile ducts
 Neoplasms 0.869 0.737 – 1.02 0.0941 158 1578 all phecode
159.4
Malignant neoplasm of retroperitoneum and
Malignant neoplasm of retroperitoneum and peritoneum
 Neoplasms 1.03 0.916 – 1.17 0.592 293 2920 all phecode
164 Cancer of intrathoracic organs Neoplasms 0.986 0.83 – 1.17 0.872 133 1324 all phecode
165 Cancer within the respiratory system Neoplasms 0.967 0.914 – 1.02 0.238 1336 13340 all phecode
165.1 Cancer of bronchus; lung Neoplasms 0.963 0.904 – 1.03 0.239 1057 10552 all phecode
170 Cancer of bone and connective tissue Neoplasms 0.985 0.938 – 1.03 0.532 1792 17850 all phecode
170.1 Bone cancer Neoplasms 0.944 0.878 – 1.02 0.127 773 7690 all phecode
170.2 Cancer of connective tissue Neoplasms 0.995 0.939 – 1.05 0.856 1266 12632 all phecode
172 Skin cancer Neoplasms 0.991 0.967 – 1.02 0.495 8608 33186 all phecode
172.1 Melanomas of skin, dx or hx Neoplasms 0.994 0.965 – 1.02 0.693 5330 30106 all phecode
172.11 Melanomas of skin Neoplasms 0.99 0.953 – 1.03 0.607 3100 25064 all phecode
172.2 Other non-epithelial cancer of skin Neoplasms 0.982 0.956 – 1.01 0.182 7095 30462 all phecode
172.21 Basal cell carcinoma Neoplasms 1.02 0.982 – 1.05 0.342 3690 23868 all phecode
172.22 Squamous cell carcinoma Neoplasms 0.994 0.952 – 1.04 0.775 2414 17683 all phecode
172.3 Carcinoma in situ of skin Neoplasms 1.06 1 – 1.12 0.0397 1482 12326 all phecode
173 Neoplasm of uncertain behavior of skin Neoplasms 0.988 0.943 – 1.04 0.621 1997 18755 all phecode
174 Breast cancer Neoplasms 1.01 0.971 – 1.05 0.614 3186 15514 all phecode
174.1 Breast cancer [female] Neoplasms 1.01 0.975 – 1.06 0.479 3036 14701 all phecode
174.11 Malignant neoplasm of female breast Neoplasms 1.02 0.979 – 1.06 0.353 2991 14639 all phecode
174.3 Neoplasm of uncertain behavior of breast Neoplasms 1.11 0.974 – 1.27 0.117 233 2307 all phecode
175 Acquired absence of breast Neoplasms 1.03 0.961 – 1.1 0.406 919 8920 all phecode
180 Cervical cancer and dysplasia Neoplasms 0.974 0.922 – 1.03 0.34 1431 12185 all phecode
180.1 Cervical cancer Neoplasms 0.933 0.852 – 1.02 0.138 500 4982 all phecode
180.3
Cervical intraepithelial neoplasia [CIN]
Cervical intraepithelial neoplasia [CIN] [Cervical dysplasia]
 Neoplasms 0.964 0.904 – 1.03 0.266 1048 9323 all phecode
182 Malignant neoplasm of uterus Neoplasms 0.935 0.868 – 1.01 0.0749 765 7613 all phecode
184 Cancer of other female genital organs Neoplasms 0.982 0.925 – 1.04 0.552 1191 11592 all phecode
184.1
Malignant neoplasm of ovary and other uterine
Malignant neoplasm of ovary and other uterine adnexa
 Neoplasms 0.976 0.896 – 1.06 0.588 573 5719 all phecode
184.11 Malignant neoplasm of ovary Neoplasms 0.997 0.902 – 1.1 0.949 432 4309 all phecode
184.2
Cancer of other female genital organs
Cancer of other female genital organs (excluding uterus and ovary)
 Neoplasms 0.963 0.885 – 1.05 0.37 608 6057 all phecode
185 Cancer of prostate Neoplasms 0.985 0.944 – 1.03 0.501 2901 10342 all phecode
187 Cancer of other male genital organs Neoplasms 1.03 0.918 – 1.15 0.63 339 3384 all phecode
187.1
Malignant neoplasm of unspecified male genital
Malignant neoplasm of unspecified male genital organ
 Neoplasms 1.01 0.826 – 1.23 0.934 115 1141 all phecode
187.2 Malignant neoplasm of testis Neoplasms 0.993 0.851 – 1.16 0.926 183 1830 all phecode
187.8
Neoplasm of uncertain behavior of male genital
Neoplasm of uncertain behavior of male genital organs
 Neoplasms 1.03 0.787 – 1.36 0.814 57 562 all phecode
189
Cancer of urinary organs (incl. kidney and
Cancer of urinary organs (incl. kidney and bladder)
 Neoplasms 1.01 0.968 – 1.05 0.746 2923 23541 all phecode
189.1 Cancer of kidney and renal pelvis Neoplasms 1.02 0.966 – 1.08 0.483 1450 14437 all phecode
189.11 Malignant neoplasm of kidney, except pelvis Neoplasms 1.03 0.969 – 1.09 0.372 1267 12655 all phecode
189.12 Malignant neoplasm of renal pelvis Neoplasms 0.996 0.873 – 1.14 0.952 237 2347 all phecode
189.2 Cancer of bladder Neoplasms 0.995 0.947 – 1.05 0.848 1783 15224 all phecode
189.21 Malignant neoplasm of bladder Neoplasms 0.985 0.936 – 1.04 0.558 1657 14178 all phecode
189.4 Malignant neoplasm of other urinary organs Neoplasms 1.02 0.944 – 1.1 0.604 678 6586 all phecode
190 Cancer of eye Neoplasms 0.963 0.805 – 1.15 0.684 138 1374 all phecode
191
Manlignant and unknown neoplasms of brain and
Manlignant and unknown neoplasms of brain and nervous system
 Neoplasms 0.973 0.914 – 1.04 0.398 1078 10771 all phecode
191.1 Cancer of brain and nervous system Neoplasms 0.983 0.91 – 1.06 0.659 706 7052 all phecode
191.11 Cancer of brain Neoplasms 1 0.921 – 1.09 0.968 600 5996 all phecode
193 Thyroid cancer Neoplasms 0.952 0.89 – 1.02 0.148 945 9393 all phecode
194 Cancer of other endocrine glands Neoplasms 0.938 0.861 – 1.02 0.143 579 5759 all phecode
195 Cancer, suspected or other Neoplasms 1 0.983 – 1.02 0.719 16962 26401 all phecode
195.1 Malignant neoplasm, other Neoplasms 1.01 0.984 – 1.03 0.636 16670 26384 all phecode
195.3 Malignant neoplasm of head, face, and neck Neoplasms 0.988 0.929 – 1.05 0.714 1103 9766 all phecode
196 Radiotherapy Neoplasms 1.01 0.969 – 1.06 0.608 2427 17006 all phecode
197 Chemotherapy Neoplasms 1.03 0.999 – 1.06 0.059 4952 23797 all phecode
198 Secondary malignant neoplasm Neoplasms 1.02 0.995 – 1.06 0.108 5801 23481 all phecode
198.1 Secondary malignancy of lymph nodes Neoplasms 1.02 0.987 – 1.06 0.213 3677 21489 all phecode
198.2 Secondary malignancy of respiratory organs Neoplasms 0.971 0.911 – 1.03 0.356 1072 10334 all phecode
198.3
Secondary malignant neoplasm of digestive
Secondary malignant neoplasm of digestive systems
 Neoplasms 1.04 0.965 – 1.11 0.329 866 8538 all phecode
198.4 Secondary malignant neoplasm of liver Neoplasms 1.09 1.01 – 1.18 0.0258 767 7558 all phecode
198.5 Secondary malignancy of brain/spine Neoplasms 0.99 0.912 – 1.07 0.811 640 6338 all phecode
198.6 Secondary malignancy of bone Neoplasms 1.05 0.98 – 1.13 0.161 866 8307 all phecode
198.7 Secondary malignant neoplasm of skin Neoplasms 0.938 0.838 – 1.05 0.262 336 3253 all phecode
199 Neoplasm of uncertain behavior Neoplasms 0.991 0.962 – 1.02 0.565 5693 25767 all phecode
199.4 Neurofibromatosis Neoplasms 1.01 0.81 – 1.25 0.958 88 880 all phecode
200 Myeloproliferative disease Neoplasms 0.983 0.924 – 1.05 0.591 1113 11098 all phecode
200.1 Polycythemia vera Neoplasms 0.956 0.837 – 1.09 0.511 231 2310 all phecode
201 Hodgkin's disease Neoplasms 0.929 0.795 – 1.08 0.351 172 1705 all phecode
202 Cancer of other lymphoid, histiocytic tissue Neoplasms 0.985 0.935 – 1.04 0.585 1559 15571 all phecode
202.2 Non-Hodgkins lymphoma Neoplasms 0.971 0.917 – 1.03 0.304 1329 13268 all phecode
202.21 Nodular lymphoma Neoplasms 0.911 0.843 – 0.984 0.0177 693 6923 all phecode
202.22 Reticulosarcoma Neoplasms 0.961 0.82 – 1.13 0.628 170 1693 all phecode
202.24 Large cell lymphoma Neoplasms 0.954 0.81 – 1.12 0.569 160 1586 all phecode
204 Leukemia Neoplasms 1 0.926 – 1.08 0.964 689 6876 all phecode
204.1 Lymphoid leukemia Neoplasms 0.883 0.774 – 1.01 0.0633 236 2354 all phecode
204.11 Lymphoid leukemia, acute Neoplasms 0.925 0.727 – 1.18 0.522 74 734 all phecode
204.12 Lymphoid leukemia, chronic Neoplasms 0.854 0.734 – 0.994 0.0411 173 1724 all phecode
204.2 Myeloid leukemia Neoplasms 1.06 0.931 – 1.2 0.384 265 2633 all phecode
204.21 Myeloid leukemia, acute Neoplasms 1 0.848 – 1.18 0.977 153 1516 all phecode
204.22 Myeloid leukemia, chronic Neoplasms 1.29 0.989 – 1.68 0.06 61 610 all phecode
204.4 Multiple myeloma Neoplasms 1.06 0.92 – 1.22 0.431 217 2162 all phecode
208 Benign neoplasm of colon Neoplasms 1.01 0.992 – 1.04 0.217 10303 34953 all phecode
209 Neuroendocrine tumors Neoplasms 0.999 0.881 – 1.13 0.992 258 2580 all phecode
210 Benign neoplasm of lip, oral cavity, and pharynx Neoplasms 0.983 0.938 – 1.03 0.49 1891 18839 all phecode
211
Benign neoplasm of other parts of digestive
Benign neoplasm of other parts of digestive system
 Neoplasms 0.983 0.959 – 1.01 0.194 7329 36606 all phecode
212
Benign neoplasm of respiratory and
Benign neoplasm of respiratory and intrathoracic organs
 Neoplasms 1.01 0.961 – 1.06 0.722 1843 18412 all phecode
213 Benign neoplasm of bone and articular cartilage Neoplasms 0.951 0.904 – 1 0.0511 1677 15527 all phecode
214 Lipoma Neoplasms 1.06 1 – 1.12 0.0376 1437 14132 all phecode
214.1 Lipoma of skin and subcutaneous tissue Neoplasms 1.06 0.991 – 1.14 0.087 883 8710 all phecode
215
Other benign neoplasm of connective and other
Other benign neoplasm of connective and other soft tissue
 Neoplasms 0.99 0.96 – 1.02 0.538 4528 39509 all phecode
216 Benign neoplasm of skin Neoplasms 1 0.982 – 1.02 0.772 11528 34919 all phecode
216.1 Screening for malignant neoplasms of the skin Neoplasms 0.94 0.804 – 1.1 0.443 174 1701 all phecode
217 Vascular hamartomas and non-neoplastic nevi Neoplasms 1 0.952 – 1.05 0.988 1786 17184 all phecode
217.1 Nevus, non-neoplastic Neoplasms 1.01 0.958 – 1.06 0.77 1679 16116 all phecode
218 Benign neoplasm of uterus Neoplasms 0.97 0.937 – 1 0.073 4301 16661 all phecode
218.1 Uterine leiomyoma Neoplasms 0.954 0.908 – 1 0.0575 1835 15733 all phecode
218.2 Other benign neoplasm of uterus Neoplasms 0.963 0.928 – 1 0.0496 3403 16447 all phecode
220 Benign neoplasm of ovary Neoplasms 1.02 0.952 – 1.09 0.571 893 8783 all phecode
221 Benign neoplasm of other female genital organs Neoplasms 0.989 0.944 – 1.04 0.63 2042 14248 all phecode
222 Benign neoplasm of male genital organs Neoplasms 0.968 0.911 – 1.03 0.304 1133 10663 all phecode
223
Benign neoplasm of kidney and other urinary
Benign neoplasm of kidney and other urinary organs
 Neoplasms 1 0.955 – 1.06 0.862 1801 12657 all phecode
224 Benign neoplasm of eye Neoplasms 0.963 0.89 – 1.04 0.347 691 6752 all phecode
224.1 Benign neoplasm of eye, uveal Neoplasms 0.988 0.907 – 1.07 0.773 595 5773 all phecode
225
Benign neoplasm of brain and other parts of
Benign neoplasm of brain and other parts of nervous system
 Neoplasms 0.974 0.918 – 1.03 0.391 1209 12074 all phecode
225.1
Benign neoplasm of brain, cranial nerves
Benign neoplasm of brain, cranial nerves, meninges
 Neoplasms 0.971 0.908 – 1.04 0.388 947 9454 all phecode
225.2 Benign neoplasm of spinal cord, meninges Neoplasms 1.06 0.933 – 1.2 0.381 289 2890 all phecode
226 Benign neoplasm of thyroid glands Neoplasms 0.974 0.921 – 1.03 0.364 1329 13264 all phecode
227
Benign neoplasm of other endocrine glands and
Benign neoplasm of other endocrine glands and related structures
 Neoplasms 0.968 0.921 – 1.02 0.207 1690 16896 all phecode
227.1 Benign neoplasm of adrenal gland Neoplasms 1.07 0.971 – 1.17 0.178 467 4644 all phecode
227.2 Benign neoplasm of parathyroid gland Neoplasms 0.967 0.899 – 1.04 0.379 795 7941 all phecode
227.3
Benign neoplasm of pituitary gland and
Benign neoplasm of pituitary gland and craniopharyngeal duct (pouch)
 Neoplasms 0.92 0.834 – 1.02 0.0997 435 4350 all phecode
228 Hemangioma and lymphangioma, any site Neoplasms 1.01 0.969 – 1.06 0.576 2149 20946 all phecode
228.1 Hemangioma of skin and subcutaneous tissue Neoplasms 1.01 0.956 – 1.07 0.71 1356 13336 all phecode
229 Benign neoplasm of unspecified sites Neoplasms 0.988 0.964 – 1.01 0.328 7767 36615 all phecode
229.1 Benign neoplasm of lymph nodes Neoplasms 0.987 0.96 – 1.02 0.374 5743 34218 all phecode
240 Simple and unspecified goiter Endocrine/metabolic 0.992 0.93 – 1.06 0.816 1031 9761 all phecode
241 Nontoxic nodular goiter Endocrine/metabolic 0.984 0.947 – 1.02 0.422 2910 22227 all phecode
241.1 Nontoxic uninodular goiter Endocrine/metabolic 0.999 0.956 – 1.04 0.966 2265 19902 all phecode
241.2 Nontoxic multinodular goiter Endocrine/metabolic 0.977 0.923 – 1.03 0.426 1304 12479 all phecode
242 Thyrotoxicosis with or without goiter Endocrine/metabolic 0.964 0.913 – 1.02 0.199 1400 13425 all phecode
242.1 Graves' disease Endocrine/metabolic 0.97 0.886 – 1.06 0.52 515 5068 all phecode
242.2 Toxic multinodular goiter Endocrine/metabolic 0.964 0.797 – 1.17 0.705 124 1224 all phecode
242.3 Exophthalmos Endocrine/metabolic 1.07 0.948 – 1.21 0.277 292 2898 all phecode
242.31 Thyrotoxic exophthalmos Endocrine/metabolic 0.924 0.777 – 1.1 0.369 144 1432 all phecode
244 Hypothyroidism Endocrine/metabolic 0.988 0.964 – 1.01 0.364 8099 32717 all phecode
244.1 Secondary hypothyroidism Endocrine/metabolic 0.97 0.924 – 1.02 0.229 1762 17230 all phecode
244.2 Acquired hypothyroidism Endocrine/metabolic 1.05 0.992 – 1.12 0.0932 1261 11982 all phecode
244.4 Hypothyroidism NOS Endocrine/metabolic 0.993 0.968 – 1.02 0.606 7542 32208 all phecode
245 Thyroiditis Endocrine/metabolic 1.01 0.939 – 1.09 0.803 832 7882 all phecode
245.2 Chronic thyroiditis Endocrine/metabolic 0.988 0.912 – 1.07 0.769 686 6517 all phecode
245.21 Chronic lymphocytic thyroiditis Endocrine/metabolic 0.981 0.906 – 1.06 0.644 679 6449 all phecode
246 Other disorders of thyroid Endocrine/metabolic 0.951 0.924 – 0.978 0.000429 6129 30240 all phecode
246.2 Thyroid cyst Endocrine/metabolic 0.921 0.748 – 1.13 0.44 101 960 all phecode
246.7 Abnormal results of function study of thyroid Endocrine/metabolic 0.997 0.931 – 1.07 0.933 886 8696 all phecode
249 Secondary diabetes mellitus Endocrine/metabolic 0.939 0.876 – 1.01 0.0714 1150 8340 all phecode
250 Diabetes mellitus Endocrine/metabolic 0.988 0.967 – 1.01 0.269 13947 31815 all phecode
250.1 Type 1 diabetes Endocrine/metabolic 0.953 0.899 – 1.01 0.106 2364 11758 all phecode
250.11 Type 1 diabetes with ketoacidosis Endocrine/metabolic 0.943 0.792 – 1.12 0.504 262 960 all phecode
250.12 Type 1 diabetes with renal manifestations Endocrine/metabolic 0.953 0.849 – 1.07 0.41 551 2686 all phecode
250.13 Type 1 diabetes with ophthalmic manifestations Endocrine/metabolic 0.99 0.888 – 1.1 0.853 784 3018 all phecode
250.14 Type 1 diabetes with neurological manifestations Endocrine/metabolic 1.03 0.923 – 1.16 0.56 638 2675 all phecode
250.15
Diabetes type 1 with peripheral circulatory
Diabetes type 1 with peripheral circulatory disorders
 Endocrine/metabolic 0.908 0.744 – 1.11 0.344 155 850 all phecode
250.2 Type 2 diabetes Endocrine/metabolic 0.975 0.95 – 0.999 0.044 9843 29688 all phecode
250.21 Type 2 diabetes with ketoacidosis Endocrine/metabolic 0.956 0.819 – 1.11 0.565 282 1327 all phecode
250.22 Type 2 diabetes with renal manifestations Endocrine/metabolic 0.97 0.918 – 1.02 0.267 1941 13510 all phecode
250.23 Type 2 diabetes with ophthalmic manifestations Endocrine/metabolic 0.978 0.917 – 1.04 0.495 1643 9668 all phecode
250.24 Type 2 diabetes with neurological manifestations Endocrine/metabolic 0.971 0.925 – 1.02 0.24 2557 16502 all phecode
250.25
Diabetes type 2 with peripheral circulatory
Diabetes type 2 with peripheral circulatory disorders
 Endocrine/metabolic 1.03 0.952 – 1.12 0.448 860 6143 all phecode
250.3 Insulin pump user Endocrine/metabolic 0.965 0.925 – 1.01 0.108 3496 20809 all phecode
250.4 Abnormal glucose Endocrine/metabolic 1.01 0.981 – 1.03 0.592 8385 30645 all phecode
250.41 Impaired fasting glucose Endocrine/metabolic 0.994 0.945 – 1.05 0.811 1870 15861 all phecode
250.42 Other abnormal glucose Endocrine/metabolic 1.01 0.984 – 1.04 0.421 7553 30071 all phecode
250.5 Glycosuria or Acetonuria Endocrine/metabolic 1.08 0.889 – 1.31 0.435 136 1067 all phecode
250.6 Polyneuropathy in diabetes Endocrine/metabolic 0.965 0.914 – 1.02 0.202 2132 13390 all phecode
250.7 Diabetic retinopathy Endocrine/metabolic 0.976 0.924 – 1.03 0.384 1691 10517 all phecode
251 Other disorders of pancreatic internal secretion Endocrine/metabolic 1 0.939 – 1.07 0.931 991 8469 all phecode
251.1 Hypoglycemia Endocrine/metabolic 1.02 0.948 – 1.09 0.663 1207 8570 all phecode
252 Disorders of parathyroid gland Endocrine/metabolic 1 0.959 – 1.05 0.953 2282 22119 all phecode
252.1 Hyperparathyroidism Endocrine/metabolic 1 0.956 – 1.05 0.985 2088 20335 all phecode
252.2 Hypoparathyroidism Endocrine/metabolic 1.01 0.918 – 1.1 0.888 508 5073 all phecode
253
Disorders of the pituitary gland and its
Disorders of the pituitary gland and its hypothalamic control
 Endocrine/metabolic 1 0.936 – 1.08 0.926 859 8544 all phecode
253.1 Pituitary hyperfunction Endocrine/metabolic 0.941 0.829 – 1.07 0.352 263 2621 all phecode
253.11 Acromegaly and gigantism Endocrine/metabolic 0.974 0.781 – 1.22 0.816 83 826 all phecode
253.2 Pituitary hypofunction Endocrine/metabolic 0.953 0.834 – 1.09 0.476 226 2250 all phecode
253.3 Diabetes insipidus Endocrine/metabolic 0.88 0.706 – 1.1 0.255 86 860 all phecode
253.4 Anterior pituitary disorders Endocrine/metabolic 0.922 0.766 – 1.11 0.389 121 1209 all phecode
253.7 Other disorders of neurohypophysis Endocrine/metabolic 1.18 0.976 – 1.44 0.0865 108 1080 all phecode
255 Disorders of adrenal glands Endocrine/metabolic 0.976 0.925 – 1.03 0.364 1506 14869 all phecode
255.1 Adrenal hyperfunction Endocrine/metabolic 0.979 0.88 – 1.09 0.689 373 3730 all phecode
255.11 Cushing's syndrome Endocrine/metabolic 0.976 0.838 – 1.14 0.758 183 1830 all phecode
255.12 Hyperaldosteronism Endocrine/metabolic 1.11 0.924 – 1.32 0.271 135 1350 all phecode
255.2 Adrenal hypofunction Endocrine/metabolic 0.992 0.914 – 1.08 0.847 626 6239 all phecode
255.21 Glucocorticoid deficiency Endocrine/metabolic 0.989 0.909 – 1.08 0.8 596 5941 all phecode
256 Ovarian dysfunction Endocrine/metabolic 0.961 0.904 – 1.02 0.205 1146 10513 all phecode
256.4 Polycystic ovaries Endocrine/metabolic 0.959 0.89 – 1.03 0.28 742 7128 all phecode
257 Testicular dysfunction Endocrine/metabolic 0.986 0.923 – 1.05 0.686 1015 9238 all phecode
257.1 Testicular hypofunction Endocrine/metabolic 0.998 0.933 – 1.07 0.959 983 8933 all phecode
258 Iatrogenic endocrine disorders Endocrine/metabolic 1.01 0.812 – 1.26 0.926 91 910 all phecode
258.1 Postablative ovarian failure Endocrine/metabolic 0.9 0.744 – 1.09 0.282 109 1090 all phecode
259 Other endocrine disorders Endocrine/metabolic 0.994 0.932 – 1.06 0.848 1038 10259 all phecode
260 Protein-calorie malnutrition Endocrine/metabolic 1.02 0.978 – 1.06 0.414 2880 26812 all phecode
260.1 Cachexia Endocrine/metabolic 1.05 0.926 – 1.18 0.469 292 2911 all phecode
260.2 severe protein-calorie malnutrition Endocrine/metabolic 1.03 0.978 – 1.08 0.281 1691 16847 all phecode
260.22 Nutritional marasmus Endocrine/metabolic 0.991 0.911 – 1.08 0.829 614 6140 all phecode
260.3 Adult failure to thrive Endocrine/metabolic 1 0.925 – 1.09 0.929 629 6236 all phecode
260.6 Anorexia Endocrine/metabolic 1.04 0.966 – 1.11 0.325 868 8591 all phecode
260.7 Polyphagia Endocrine/metabolic 1.01 0.783 – 1.31 0.912 65 643 all phecode
261 Vitamin deficiency Endocrine/metabolic 1.01 0.981 – 1.03 0.656 7718 35203 all phecode
261.1 Vitamin A deficiency Endocrine/metabolic 0.991 0.779 – 1.26 0.941 69 690 all phecode
261.2 Vitamin B-complex deficiencies Endocrine/metabolic 0.989 0.922 – 1.06 0.765 857 8405 all phecode
261.4 Vitamin D deficiency Endocrine/metabolic 1.01 0.984 – 1.04 0.458 7255 35225 all phecode
261.41 Rickets or osteomalacia Endocrine/metabolic 1.05 0.788 – 1.39 0.749 52 511 all phecode
262 Mineral deficiency NEC Endocrine/metabolic 1.02 0.959 – 1.08 0.558 1182 11676 all phecode
263 Other nutritional deficiency Endocrine/metabolic 1.01 0.958 – 1.06 0.749 1651 15788 all phecode
264 Lack of normal physiological development Endocrine/metabolic 0.969 0.847 – 1.11 0.648 239 2301 all phecode
264.2 Failure to thrive (childhood) Endocrine/metabolic 1.05 0.874 – 1.26 0.601 122 1220 all phecode
264.9
Lack of normal physiological development
Lack of normal physiological development, unspecified
 Endocrine/metabolic 0.843 0.674 – 1.06 0.137 81 772 all phecode
269 Proteinuria Endocrine/metabolic 1.04 0.989 – 1.1 0.127 1694 13981 all phecode
270
Disorders of protein plasma/amino-acid
Disorders of protein plasma/amino-acid transport and metabolism
 Endocrine/metabolic 0.99 0.927 – 1.06 0.773 967 9575 all phecode
270.1 Disturbances of amino-acid transport Endocrine/metabolic 0.96 0.817 – 1.13 0.618 170 1697 all phecode
270.11
Disturbances of sulphur-bearing amino-acid
Disturbances of sulphur-bearing amino-acid metabolism
 Endocrine/metabolic 0.936 0.779 – 1.12 0.481 134 1334 all phecode
270.2 Disorders of amino-acid metabolism Endocrine/metabolic 0.786 0.642 – 0.962 0.0195 96 954 all phecode
270.3 Disorders of plasma protein metabolism Endocrine/metabolic 1.03 0.956 – 1.11 0.429 737 7303 all phecode
270.32 Paraproteinemia Endocrine/metabolic 1.02 0.917 – 1.13 0.728 384 3781 all phecode
270.33 Amyloidosis Endocrine/metabolic 1.1 0.87 – 1.38 0.434 71 695 all phecode
270.34 Alpha-1-antitrypsin deficiency Endocrine/metabolic 1.03 0.816 – 1.29 0.817 69 690 all phecode
270.38
Other specified disorders of plasma protein
Other specified disorders of plasma protein metabolism
 Endocrine/metabolic 1.05 0.928 – 1.18 0.458 299 2984 all phecode
271
Disorders of carbohydrate transport and
Disorders of carbohydrate transport and metabolism
 Endocrine/metabolic 0.999 0.961 – 1.04 0.965 2907 28132 all phecode
271.3
Intestinal disaccharidase deficiencies and
Intestinal disaccharidase deficiencies and disaccharide malabsorption
 Endocrine/metabolic 1 0.963 – 1.04 0.942 2827 27425 all phecode
271.9
Other disorders of carbohydrate transport and
Other disorders of carbohydrate transport and metabolism
 Endocrine/metabolic 0.907 0.75 – 1.1 0.316 102 1007 all phecode
272 Disorders of lipoid metabolism Endocrine/metabolic 1.35 1.32 – 1.38 1.45e-170 18881 26670 all phecode
272.1 Hyperlipidemia Endocrine/metabolic 1.35 1.33 – 1.38 3.16e-171 18843 26654 all phecode
272.11 Hypercholesterolemia Endocrine/metabolic 1.48 1.44 – 1.53 1.72e-125 5928 21600 all phecode
272.12 Hyperglyceridemia Endocrine/metabolic 1.14 1.07 – 1.2 1.7e-05 1360 11837 all phecode
272.13 Mixed hyperlipidemia Endocrine/metabolic 1.41 1.35 – 1.46 1.61e-62 3538 18449 all phecode
272.9 Unspecified disorder of lipoid metabolism Endocrine/metabolic 1.19 1.06 – 1.34 0.00391 313 3011 all phecode
274 Gout and other crystal arthropathies Endocrine/metabolic 0.986 0.947 – 1.03 0.516 2524 22729 all phecode
274.1 Gout Endocrine/metabolic 0.99 0.95 – 1.03 0.654 2409 21991 all phecode
274.11 Gouty arthropathy Endocrine/metabolic 0.979 0.919 – 1.04 0.503 1082 10576 all phecode
274.2 Crystal arthropathies Endocrine/metabolic 0.981 0.845 – 1.14 0.799 195 1890 all phecode
274.21 Chondrocalcinosis Endocrine/metabolic 0.974 0.836 – 1.14 0.741 183 1772 all phecode
275 Disorders of mineral metabolism Endocrine/metabolic 0.984 0.953 – 1.02 0.302 4357 37091 all phecode
275.1 Disorders of iron metabolism Hematopoietic 0.871 0.758 – 1 0.0511 218 2180 all phecode
275.11 Hereditary hemochromatosis Hematopoietic 0.782 0.643 – 0.952 0.0143 99 990 all phecode
275.2 Disorders of copper metabolism Endocrine/metabolic 0.867 0.672 – 1.12 0.272 62 614 all phecode
275.3 Disorders of magnesium metabolism Endocrine/metabolic 1.02 0.96 – 1.08 0.513 1154 11504 all phecode
275.5 Disorders of calcium/phosphorus metabolism Endocrine/metabolic 0.978 0.944 – 1.01 0.23 3369 31544 all phecode
275.51 Hypocalcemia Endocrine/metabolic 0.935 0.873 – 1 0.0555 898 8969 all phecode
275.53 Disorders of phosphorus metabolism Endocrine/metabolic 0.969 0.917 – 1.02 0.266 1366 13634 all phecode
275.6 Hypercalcemia Endocrine/metabolic 0.996 0.943 – 1.05 0.886 1468 14183 all phecode
276
Disorders of fluid, electrolyte, and acid-base
Disorders of fluid, electrolyte, and acid-base balance
 Endocrine/metabolic 0.999 0.977 – 1.02 0.964 9238 37046 all phecode
276.1 Electrolyte imbalance Endocrine/metabolic 1 0.974 – 1.03 0.976 6352 34366 all phecode
276.11 Hyperosmolality and/or hypernatremia Endocrine/metabolic 0.994 0.912 – 1.08 0.89 550 5434 all phecode
276.12 Hyposmolality and/or hyponatremia Endocrine/metabolic 1.02 0.974 – 1.06 0.472 2514 23219 all phecode
276.13 Hyperpotassemia Endocrine/metabolic 0.989 0.952 – 1.03 0.572 2992 25216 all phecode
276.14 Hypopotassemia Endocrine/metabolic 1.01 0.962 – 1.05 0.806 2148 20909 all phecode
276.4 Acid-base balance disorder Endocrine/metabolic 1.02 0.974 – 1.07 0.403 2086 20332 all phecode
276.41 Acidosis Endocrine/metabolic 1.01 0.962 – 1.06 0.695 1788 17572 all phecode
276.42 Alkalosis Endocrine/metabolic 1.08 0.987 – 1.19 0.091 476 4741 all phecode
276.5 Hypovolemia Endocrine/metabolic 1 0.972 – 1.03 0.88 4574 34527 all phecode
276.6 Fluid overload Endocrine/metabolic 0.966 0.914 – 1.02 0.215 1384 13211 all phecode
276.8 Polydipsia Endocrine/metabolic 1.17 0.969 – 1.42 0.102 124 1240 all phecode
277 Other disorders of metabolism Endocrine/metabolic 0.997 0.965 – 1.03 0.86 4112 35070 all phecode
277.2
Other disorders of purine and pyrimidine
Other disorders of purine and pyrimidine metabolism
 Endocrine/metabolic 0.958 0.863 – 1.06 0.414 403 3991 all phecode
277.4 Disorders of bilirubin excretion Endocrine/metabolic 0.983 0.909 – 1.06 0.656 720 7161 all phecode
277.5 Other disorders of lipoid metabolism Endocrine/metabolic 0.94 0.878 – 1.01 0.0747 936 9270 all phecode
277.51 Lipoprotein disorders Endocrine/metabolic 0.929 0.862 – 1 0.055 773 7668 all phecode
277.7 Dysmetabolic syndrome X Endocrine/metabolic 1.03 0.964 – 1.11 0.369 916 8359 all phecode
278 Overweight, obesity and other hyperalimentation Endocrine/metabolic 0.989 0.97 – 1.01 0.232 19419 27331 all phecode
278.1 Obesity Endocrine/metabolic 0.985 0.966 – 1 0.136 17129 27321 all phecode
278.11 Morbid obesity Endocrine/metabolic 0.975 0.951 – 0.999 0.0455 8280 27172 all phecode
278.3 Localized adiposity Endocrine/metabolic 0.87 0.777 – 0.976 0.0172 324 3228 all phecode
278.4 Abnormal weight gain Endocrine/metabolic 1 0.958 – 1.05 0.913 2104 17411 all phecode
279 Disorders involving the immune mechanism Endocrine/metabolic 0.984 0.947 – 1.02 0.412 2934 28612 all phecode
279.1 Immunity deficiency Endocrine/metabolic 0.988 0.93 – 1.05 0.695 1161 11571 all phecode
279.11 Deficiency of humoral immunity Endocrine/metabolic 0.962 0.86 – 1.08 0.504 330 3278 all phecode
279.2 Autoimmune disease NEC Endocrine/metabolic 0.969 0.899 – 1.05 0.417 754 7516 all phecode
279.7 Other immunological findings Endocrine/metabolic 1 0.975 – 1.04 0.769 4885 36552 all phecode
279.8
Other specified disorders involving the immune
Other specified disorders involving the immune mechanism
 Endocrine/metabolic 0.934 0.859 – 1.02 0.11 601 5988 all phecode
280 Iron deficiency anemias Hematopoietic 1.03 0.999 – 1.06 0.0598 4626 30873 all phecode
280.1
Iron deficiency anemias, unspecified or not due
Iron deficiency anemias, unspecified or not due to blood loss
 Hematopoietic 1.03 0.995 – 1.06 0.0991 4484 30649 all phecode
280.2
Iron deficiency anemia secondary to blood loss
Iron deficiency anemia secondary to blood loss (chronic)
 Hematopoietic 1.02 0.972 – 1.07 0.407 1771 17196 all phecode
281 Other deficiency anemia Hematopoietic 1.01 0.92 – 1.1 0.875 519 5120 all phecode
281.1 Megaloblastic anemia Hematopoietic 0.959 0.842 – 1.09 0.522 253 2497 all phecode
281.11 Pernicious anemia Hematopoietic 0.867 0.713 – 1.05 0.152 114 1108 all phecode
281.12 Other vitamin B12 deficiency anemia Hematopoietic 0.953 0.821 – 1.11 0.524 187 1817 all phecode
281.9 Deficiency anemias Hematopoietic 1.05 0.925 – 1.19 0.453 285 2830 all phecode
282 Hereditary hemolytic anemias Hematopoietic 0.96 0.855 – 1.08 0.482 323 3188 all phecode
282.8 Other hemoglobinopathies Hematopoietic 0.908 0.79 – 1.04 0.176 216 2113 all phecode
282.9 Other hereditary hemolytic anemias Hematopoietic 1.01 0.872 – 1.17 0.879 192 1920 all phecode
283 Acquired hemolytic anemias Hematopoietic 0.984 0.83 – 1.17 0.849 155 1550 all phecode
283.1 Autoimmune hemolytic anemias Hematopoietic 1.04 0.806 – 1.34 0.767 64 633 all phecode
284 Aplastic anemia Hematopoietic 1.04 0.957 – 1.12 0.387 697 6943 all phecode
284.1 Pancytopenia Hematopoietic 1.06 0.971 – 1.15 0.202 612 6100 all phecode
285 Other anemias Hematopoietic 1.01 0.992 – 1.04 0.226 11794 33591 all phecode
285.1 Acute posthemorrhagic anemia Hematopoietic 1.02 0.983 – 1.06 0.294 3325 27709 all phecode
285.2 Anemia of chronic disease Hematopoietic 1.02 0.977 – 1.07 0.337 2055 19939 all phecode
285.21 Anemia in chronic kidney disease Hematopoietic 0.992 0.926 – 1.06 0.817 932 9106 all phecode
285.22 Anemia in neoplastic disease Hematopoietic 1.02 0.944 – 1.11 0.582 690 6892 all phecode
286 Coagulation defects Hematopoietic 1 0.971 – 1.04 0.808 3844 33384 all phecode
286.1 Congenital coagulation defects Hematopoietic 0.915 0.803 – 1.04 0.177 250 2466 all phecode
286.11 Von willebrand's disease Hematopoietic 0.979 0.78 – 1.23 0.851 83 822 all phecode
286.12
Congenital deficiency of other clotting factors
Congenital deficiency of other clotting factors (including factor VII)
 Hematopoietic 0.859 0.719 – 1.03 0.093 126 1260 all phecode
286.2
Encounter for long-term (current) use of
Encounter for long-term (current) use of anticoagulants
 Hematopoietic 1.02 0.988 – 1.06 0.194 3354 25918 all phecode
286.3
Coagulation defects complicating pregnancy or
Coagulation defects complicating pregnancy or postpartum
 Hematopoietic 0.714 0.583 – 0.874 0.00109 97 962 all phecode
286.4 Acquired coagulation factor deficiency Hematopoietic 1 0.879 – 1.14 0.995 254 2529 all phecode
286.5
Hemorrhagic disorder due to intrinsic
Hemorrhagic disorder due to intrinsic circulating anticoagulants
 Hematopoietic 1.14 0.954 – 1.37 0.147 132 1294 all phecode
286.6 Defibrination syndrome Hematopoietic 1 0.961 – 1.04 0.963 2579 25377 all phecode
286.7 Other and unspecified coagulation defects Hematopoietic 0.997 0.961 – 1.04 0.885 3014 29294 all phecode
286.8 Hypercoagulable state Hematopoietic 0.981 0.914 – 1.05 0.588 846 8437 all phecode
286.81 Primary hypercoagulable state Hematopoietic 0.968 0.901 – 1.04 0.375 813 8111 all phecode
286.9 Abnormal coagulation profile Hematopoietic 1.01 0.955 – 1.08 0.64 1182 11487 all phecode
287 Purpura and other hemorrhagic conditions Hematopoietic 1.04 1 – 1.08 0.0456 3288 28474 all phecode
287.1 Spontaneous ecchymoses Hematopoietic 1.07 0.924 – 1.23 0.379 211 2094 all phecode
287.3 Thrombocytopenia Hematopoietic 1.04 1 – 1.08 0.0387 2938 26323 all phecode
287.31 Primary thrombocytopenia Hematopoietic 1.06 0.975 – 1.15 0.17 601 5994 all phecode
287.32 Secondary thrombocytopenia Hematopoietic 1.03 0.944 – 1.12 0.508 569 5686 all phecode
287.4 Qualitative platelet defects Hematopoietic 1.19 0.986 – 1.44 0.0698 112 1120 all phecode
288 Diseases of white blood cells Hematopoietic 0.983 0.954 – 1.01 0.265 4886 36527 all phecode
288.1 Decreased white blood cell count Hematopoietic 0.993 0.943 – 1.05 0.796 1599 15951 all phecode
288.11 Neutropenia Hematopoietic 0.976 0.916 – 1.04 0.441 1106 11041 all phecode
288.2 Elevated white blood cell count Hematopoietic 0.976 0.945 – 1.01 0.15 4082 35079 all phecode
288.3 Eosinophilia Hematopoietic 0.938 0.811 – 1.08 0.384 187 1866 all phecode
289 Other diseases of blood and blood-forming organs Hematopoietic 0.973 0.926 – 1.02 0.276 1757 17434 all phecode
289.3
Personal history of diseases of blood and
Personal history of diseases of blood and blood-forming organs
 Hematopoietic 1.03 0.957 – 1.1 0.475 918 9087 all phecode
289.4 Lymphadenitis Hematopoietic 0.981 0.948 – 1.01 0.249 3888 34715 all phecode
289.5 Diseases of spleen Hematopoietic 1.01 0.91 – 1.12 0.848 393 3913 all phecode
289.8 Polycythemia, secondary Hematopoietic 0.882 0.778 – 1 0.0512 255 2550 all phecode
289.9 Abnormality of red blood cells Hematopoietic 0.935 0.844 – 1.04 0.2 385 3813 all phecode
290
Delirium dementia and amnestic and other
Delirium dementia and amnestic and other cognitive disorders
 Mental Disorders 1.03 0.975 – 1.09 0.271 1318 11547 all phecode
290.1 Dementias Mental Disorders 1.08 0.992 – 1.19 0.073 541 4910 all phecode
290.11 Alzheimer's disease Mental Disorders 1.18 0.995 – 1.39 0.057 151 1389 all phecode
290.12 Dementia with cerebral degenerations Mental Disorders 0.917 0.738 – 1.14 0.436 88 846 all phecode
290.13 Senile dementia Mental Disorders 1.07 0.957 – 1.2 0.234 340 3078 all phecode
290.16 Vascular dementia Mental Disorders 1.07 0.85 – 1.35 0.563 81 777 all phecode
290.2 Delirium due to conditions classified elsewhere Mental Disorders 0.995 0.924 – 1.07 0.9 750 7358 all phecode
290.3
Other persistent mental disorders due to
Other persistent mental disorders due to conditions classified elsewhere
 Mental Disorders 1.07 0.995 – 1.14 0.0708 886 8618 all phecode
291
Other specified nonpsychotic and/or transient
Other specified nonpsychotic and/or transient mental disorders
 Mental Disorders 0.997 0.957 – 1.04 0.88 2550 24810 all phecode
291.1
Transient mental disorders due to conditions
Transient mental disorders due to conditions classified elsewhere
 Mental Disorders 0.957 0.823 – 1.11 0.567 175 1750 all phecode
291.4
Specific nonpsychotic mental disorders due to
Specific nonpsychotic mental disorders due to brain damage
 Mental Disorders 1.03 0.935 – 1.13 0.584 484 4807 all phecode
291.8 Alteration of consciousness Mental Disorders 1.01 0.961 – 1.05 0.804 2036 19974 all phecode
292 Neurological disorders Mental Disorders 0.982 0.955 – 1.01 0.199 5733 38553 all phecode
292.1 Aphasia/speech disturbance Mental Disorders 0.977 0.933 – 1.02 0.332 2013 19867 all phecode
292.11 Aphasia Mental Disorders 0.959 0.885 – 1.04 0.31 664 6581 all phecode
292.12 Symbolic dysfunction Mental Disorders 0.931 0.804 – 1.08 0.334 200 1988 all phecode
292.2 Mild cognitive impairment Mental Disorders 1.03 0.928 – 1.15 0.566 389 3731 all phecode
292.3 Memory loss Mental Disorders 1.03 0.986 – 1.08 0.174 1922 18158 all phecode
292.4 Altered mental status Mental Disorders 0.974 0.934 – 1.02 0.22 2454 22725 all phecode
292.5 Transient alteration of awareness Mental Disorders 0.956 0.866 – 1.06 0.374 430 4285 all phecode
292.6 Hallucinations Mental Disorders 0.894 0.784 – 1.02 0.0968 217 2147 all phecode
293 Symptoms involving head and neck Mental Disorders 0.954 0.862 – 1.06 0.358 414 4127 all phecode
293.1
Swelling, mass, or lump in head and neck
Swelling, mass, or lump in head and neck [Space-occupying lesion, intracranial NOS]
 Mental Disorders 0.999 0.968 – 1.03 0.929 4417 38609 all phecode
295 Schizophrenia and other psychotic disorders Mental Disorders 0.933 0.87 – 1 0.0534 885 8229 all phecode
295.1 Schizophrenia Mental Disorders 0.972 0.814 – 1.16 0.755 138 1339 all phecode
295.2 Paranoid disorders Mental Disorders 0.816 0.674 – 0.989 0.0378 118 1079 all phecode
295.3 Psychosis Mental Disorders 0.947 0.876 – 1.02 0.174 716 6694 all phecode
296 Mood disorders Mental Disorders 1 0.983 – 1.03 0.681 15356 20858 all phecode
296.1 Bipolar Mental Disorders 0.998 0.941 – 1.06 0.934 1301 11264 all phecode
296.2 Depression Mental Disorders 1 0.983 – 1.03 0.666 14833 20856 all phecode
296.22 Major depressive disorder Mental Disorders 1 0.981 – 1.03 0.809 13850 20853 all phecode
297 Suicidal ideation or attempt Mental Disorders 0.971 0.907 – 1.04 0.383 985 9050 all phecode
297.1 Suicidal ideation Mental Disorders 0.999 0.927 – 1.08 0.979 788 7310 all phecode
297.2 Suicide or self-inflicted injury Mental Disorders 0.962 0.85 – 1.09 0.539 285 2654 all phecode
300 Anxiety disorders Mental Disorders 1 0.978 – 1.02 0.966 15419 20850 all phecode
300.1 Anxiety disorder Mental Disorders 1 0.98 – 1.02 0.87 14517 20855 all phecode
300.11 Generalized anxiety disorder Mental Disorders 0.989 0.959 – 1.02 0.473 5546 20512 all phecode
300.12 Agorophobia, social phobia, and panic disorder Mental Disorders 1 0.943 – 1.06 0.994 1360 11377 all phecode
300.13 Phobia Mental Disorders 0.99 0.926 – 1.06 0.761 1051 9542 all phecode
300.3 Obsessive-compulsive disorders Mental Disorders 0.87 0.774 – 0.978 0.0194 328 3018 all phecode
300.4 Dysthymic disorder Mental Disorders 0.999 0.956 – 1.04 0.951 2420 16552 all phecode
300.8 Acute reaction to stress Mental Disorders 0.979 0.892 – 1.07 0.654 504 4825 all phecode
300.9 Posttraumatic stress disorder Mental Disorders 0.995 0.925 – 1.07 0.895 843 7909 all phecode
301 Personality disorders Mental Disorders 1.01 0.912 – 1.11 0.916 477 4539 all phecode
301.2 Antisocial/borderline personality disorder Mental Disorders 1.05 0.92 – 1.2 0.464 254 2393 all phecode
302 Sexual and gender identity disorders Mental Disorders 0.969 0.933 – 1.01 0.0957 3700 13808 all phecode
302.1 Decreased libido Mental Disorders 0.902 0.816 – 0.996 0.0423 447 4331 all phecode
303 Psychogenic and somatoform disorders Mental Disorders 1.01 0.979 – 1.04 0.631 6808 20043 all phecode
303.1 Dissociative disorder Mental Disorders 0.903 0.769 – 1.06 0.214 161 1573 all phecode
303.3 Psychogenic disorder Mental Disorders 1.01 0.977 – 1.03 0.707 6487 19888 all phecode
303.31
Gastrointestinal malfunction arising from
Gastrointestinal malfunction arising from mental factors
 Mental Disorders 0.943 0.855 – 1.04 0.234 471 4623 all phecode
303.4 Somatoform disorder Mental Disorders 1.02 0.963 – 1.09 0.465 1177 11180 all phecode
304 Adjustment reaction Mental Disorders 1 0.965 – 1.04 0.989 3888 20475 all phecode
305.2 Eating disorder Mental Disorders 0.967 0.902 – 1.04 0.339 901 8329 all phecode
306 Other mental disorder Mental Disorders 0.98 0.933 – 1.03 0.423 1815 14133 all phecode
306.1 Mental disorders durring/after pregnancy Mental Disorders 1.03 0.94 – 1.12 0.546 587 3527 all phecode
306.9 Tension headache Mental Disorders 0.975 0.903 – 1.05 0.511 753 7277 all phecode
312 Conduct disorders Mental Disorders 0.969 0.854 – 1.1 0.633 254 2501 all phecode
312.3 Impulse control disorder Mental Disorders 0.957 0.747 – 1.22 0.725 74 736 all phecode
313 Pervasive developmental disorders Mental Disorders 0.992 0.941 – 1.05 0.759 1571 14633 all phecode
313.1 Attention deficit hyperactivity disorder Mental Disorders 0.989 0.935 – 1.05 0.701 1392 13190 all phecode
313.2 Tics and stuttering Mental Disorders 0.961 0.765 – 1.21 0.73 77 770 all phecode
313.3 Autism Mental Disorders 1.01 0.789 – 1.3 0.918 64 621 all phecode
315 Develomental delays and disorders Mental Disorders 1.03 0.953 – 1.11 0.455 684 6788 all phecode
315.1 Learning disorder Mental Disorders 1.05 0.84 – 1.31 0.676 87 860 all phecode
315.2 Speech and language disorder Mental Disorders 1.08 0.945 – 1.23 0.264 254 2539 all phecode
316 Substance addiction and disorders Mental Disorders 0.989 0.956 – 1.02 0.541 3682 32680 all phecode
316.1 Polyneuropathy due to drugs Mental Disorders 1.01 0.927 – 1.09 0.863 634 6331 all phecode
317 Alcohol-related disorders Mental Disorders 1.01 0.967 – 1.05 0.732 2525 22920 all phecode
317.1 Alcoholism Mental Disorders 1.01 0.961 – 1.05 0.794 1986 19339 all phecode
317.11 Alcoholic liver damage Mental Disorders 0.962 0.869 – 1.07 0.459 408 4080 all phecode
318 Tobacco use disorder Mental Disorders 1.01 0.988 – 1.04 0.331 8622 34842 all phecode
320 Meningitis Neurological 1.06 0.953 – 1.17 0.29 382 3820 all phecode
323 Encephalitis Neurological 1 0.863 – 1.16 0.992 181 1809 all phecode
323.8 Encephalitis, non-infectious Neurological 0.959 0.818 – 1.13 0.611 153 1527 all phecode
324 Other CNS infection and poliomyelitis Neurological 0.972 0.864 – 1.09 0.638 288 2880 all phecode
325
Phlebitis and thrombophlebitis of intracranial
Phlebitis and thrombophlebitis of intracranial venous sinuses
 Neurological 0.898 0.675 – 1.19 0.46 53 530 all phecode
327 Sleep disorders Neurological 0.994 0.974 – 1.01 0.526 14941 31602 all phecode
327.1 Hypersomnia Neurological 0.994 0.95 – 1.04 0.81 2061 19110 all phecode
327.3 Sleep apnea Neurological 0.996 0.974 – 1.02 0.72 10909 31304 all phecode
327.31 Central/nonobstroctive sleep apnea Neurological 0.953 0.868 – 1.05 0.305 492 4784 all phecode
327.32 Obstructive sleep apnea Neurological 0.992 0.969 – 1.02 0.542 8744 30530 all phecode
327.4 Insomnia Neurological 0.988 0.96 – 1.02 0.429 5524 30960 all phecode
327.41 Organic or persistent insomnia Neurological 0.963 0.909 – 1.02 0.207 1265 12120 all phecode
327.5 Parasomnia Neurological 0.923 0.849 – 1 0.0614 604 5913 all phecode
327.6 Circadian rhythm sleep disorder Neurological 0.86 0.757 – 0.977 0.0202 274 2666 all phecode
327.7 Sleep related movement disorders Neurological 0.958 0.913 – 1.01 0.0842 1786 17323 all phecode
327.71 Restless legs syndrome Neurological 0.949 0.901 – 1 0.0482 1570 15360 all phecode
327.72 Sleep related leg cramps Neurological 1.07 0.855 – 1.33 0.566 83 822 all phecode
331 Other cerebral degenerations Neurological 1.04 0.961 – 1.12 0.341 717 7024 all phecode
331.1 Hydrocephalus Neurological 0.981 0.869 – 1.11 0.761 284 2836 all phecode
331.9 Cerebral degeneration, unspecified Neurological 1.05 0.945 – 1.16 0.385 419 4026 all phecode
332 Parkinson's disease Neurological 0.896 0.81 – 0.99 0.0311 415 4128 all phecode
333
Extrapyramidal disease and abnormal movement
Extrapyramidal disease and abnormal movement disorders
 Neurological 0.975 0.938 – 1.01 0.19 2868 26583 all phecode
333.1 Essential tremor Neurological 0.975 0.904 – 1.05 0.518 725 7163 all phecode
333.2 Myoclonus Neurological 1.1 0.931 – 1.3 0.264 159 1590 all phecode
333.4 Torsion dystonia Neurological 1.02 0.911 – 1.14 0.743 352 3504 all phecode
333.8 Other degenerative diseases of the basal ganglia Neurological 1.03 0.826 – 1.28 0.792 89 890 all phecode
334 Degenerative disease of the spinal cord Neurological 0.94 0.882 – 1 0.0532 1058 10562 all phecode
334.1 Spinocerebellar disease Neurological 0.819 0.643 – 1.04 0.108 79 790 all phecode
334.2 Anterior horn cell disease Neurological 0.792 0.654 – 0.959 0.017 110 1080 all phecode
334.21 Amyotrophic Lateral Sclerosis Neurological 0.722 0.572 – 0.911 0.00602 71 693 all phecode
335 Multiple sclerosis Neurological 1 0.903 – 1.11 0.985 396 3951 all phecode
337 Disorders of the autonomic nervous system Neurological 0.952 0.886 – 1.02 0.185 808 7413 all phecode
337.1 Peripheral autonomic neuropathy Neurological 0.959 0.86 – 1.07 0.448 370 3164 all phecode
338 Pain Neurological 1 0.982 – 1.02 0.996 20346 26417 all phecode
338.1 Acute pain Neurological 0.995 0.975 – 1.02 0.623 15582 26313 all phecode
338.2 Chronic pain Neurological 1 0.978 – 1.02 0.998 10994 26368 all phecode
339 Other headache syndromes Neurological 1 0.977 – 1.02 0.973 9242 34658 all phecode
340 Migraine Neurological 1 0.975 – 1.03 0.865 6708 30587 all phecode
340.1 Migrain with aura Neurological 1.01 0.979 – 1.05 0.416 3624 23684 all phecode
341
Other demyelinating diseases of central nervous
Other demyelinating diseases of central nervous system
 Neurological 0.96 0.802 – 1.15 0.655 133 1330 all phecode
342 Hemiplegia Neurological 0.942 0.857 – 1.04 0.218 464 4607 all phecode
343 Infantile cerebral palsy Neurological 1.01 0.806 – 1.26 0.955 85 847 all phecode
344 Other paralytic syndromes Neurological 1.05 0.971 – 1.14 0.219 682 6808 all phecode
345 Epilepsy, recurrent seizures, convulsions Neurological 0.953 0.915 – 0.993 0.0208 2553 25307 all phecode
345.1 Epilepsy Neurological 0.874 0.811 – 0.942 0.000437 747 7465 all phecode
345.11 Generalized convulsive epilepsy Neurological 0.896 0.783 – 1.03 0.113 233 2330 all phecode
345.12 Partial epilepsy Neurological 0.892 0.817 – 0.974 0.0112 534 5335 all phecode
345.3 Convulsions Neurological 0.943 0.905 – 0.984 0.00653 2396 23796 all phecode
346
Abnormal findings on study of brain and/or
Abnormal findings on study of brain and/or nervous system
 Neurological 1.01 0.869 – 1.18 0.885 183 1824 all phecode
346.1
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of skull and head
 Neurological 1.01 0.959 – 1.07 0.667 1472 14587 all phecode
346.2
Nonspecific abnormal results of function study
Nonspecific abnormal results of function study of brain and central nervous system
 Neurological 1.07 0.886 – 1.29 0.481 120 1181 all phecode
346.3
Nonspecific abnormal findings in cerebrospinal
Nonspecific abnormal findings in cerebrospinal fluid
 Neurological 0.816 0.677 – 0.983 0.0324 110 1100 all phecode
347 Cataplexy and narcolepsy Neurological 0.968 0.792 – 1.18 0.753 101 1010 all phecode
348 Other conditions of brain Neurological 0.995 0.948 – 1.05 0.856 1793 17894 all phecode
348.2 Cerebral edema and compression of brain Neurological 0.969 0.905 – 1.04 0.365 905 9034 all phecode
348.4 Cerebral cysts Neurological 0.954 0.834 – 1.09 0.489 229 2290 all phecode
348.7 Coma Neurological 1.13 0.989 – 1.3 0.0725 229 2275 all phecode
348.8 Encephalopathy, not elsewhere classified Neurological 1.04 0.97 – 1.12 0.27 853 8479 all phecode
348.9 Other conditions of brain, NOS Neurological 0.994 0.953 – 1.04 0.776 2341 23287 all phecode
349
Other and unspecified disorders of the nervous
Other and unspecified disorders of the nervous system
 Neurological 1.01 0.943 – 1.08 0.8 941 9385 all phecode
350 Abnormal movement Neurological 0.98 0.955 – 1.01 0.131 6706 38762 all phecode
350.1 Abnormal involuntary movements Neurological 0.983 0.949 – 1.02 0.366 3273 30524 all phecode
350.2 Abnormality of gait Neurological 0.964 0.933 – 0.997 0.0345 3920 30520 all phecode
350.3 Lack of coordination Neurological 0.984 0.924 – 1.05 0.625 1062 10554 all phecode
350.5 Abnormal reflex Neurological 0.912 0.791 – 1.05 0.211 200 1988 all phecode
350.6 Disturbances of sensation of smell and taste Neurological 1.02 0.931 – 1.11 0.733 558 5576 all phecode
351 Other peripheral nerve disorders Neurological 0.989 0.964 – 1.01 0.381 7401 34460 all phecode
352 Disorders of other cranial nerves Neurological 0.961 0.914 – 1.01 0.118 1714 17106 all phecode
352.1 Trigeminal nerve disorders [CN5] Neurological 0.877 0.802 – 0.958 0.00381 535 5344 all phecode
352.2 Facial nerve disorders [CN7] Neurological 0.97 0.901 – 1.04 0.423 783 7826 all phecode
353 Nerve root and plexus disorders Neurological 0.987 0.956 – 1.02 0.442 4256 33369 all phecode
353.1 Nerve plexus lesions Neurological 1.01 0.913 – 1.13 0.789 390 3900 all phecode
353.2 Nerve root lesions Neurological 0.908 0.766 – 1.08 0.27 130 1287 all phecode
355 Complex regional/central pain syndrome Neurological 0.885 0.81 – 0.967 0.00716 531 5295 all phecode
355.1 Chronic pain syndrome Neurological 0.96 0.894 – 1.03 0.255 843 8386 all phecode
356 Hereditary and idiopathic peripheral neuropathy Neurological 0.962 0.921 – 1 0.0739 2335 20731 all phecode
357 Inflammatory and toxic neuropathy Neurological 0.99 0.956 – 1.03 0.578 3472 29956 all phecode
358 Myoneural disorders Neurological 0.993 0.935 – 1.06 0.822 1147 11391 all phecode
358.1 Myasthenia gravis Neurological 1.06 0.863 – 1.31 0.568 109 1082 all phecode
359 Muscular dystrophies and other myopathies Neurological 0.946 0.891 – 1.01 0.0759 1134 11274 all phecode
359.1 Muscular dystrophies Neurological 0.76 0.59 – 0.981 0.0349 64 632 all phecode
359.2 Myopathy Neurological 0.95 0.893 – 1.01 0.104 1092 10843 all phecode
360 Disorders of the globe Sense Organs 1.02 0.853 – 1.22 0.83 131 1276 all phecode
360.2 Progressive myopia Sense Organs 1.04 0.809 – 1.33 0.777 65 640 all phecode
361 Retinal detachments and defects Sense Organs 0.963 0.893 – 1.04 0.328 733 7131 all phecode
361.1 Retinal detachment with retinal defect Sense Organs 0.976 0.869 – 1.1 0.683 302 2962 all phecode
362 Other retinal disorders Sense Organs 1.03 0.99 – 1.06 0.154 3569 22997 all phecode
362.2
Degeneration of macula and posterior pole of
Degeneration of macula and posterior pole of retina
 Sense Organs 1.05 1 – 1.1 0.0518 2172 15483 all phecode
362.21 Macular degeneration, dry Sense Organs 0.996 0.901 – 1.1 0.94 419 3438 all phecode
362.22 Macular degeneration, wet Sense Organs 0.968 0.82 – 1.14 0.698 148 1184 all phecode
362.23 Cystoid macular degeneration of retina Sense Organs 1.07 0.964 – 1.18 0.214 408 3839 all phecode
362.26 Macular puckering of retina Sense Organs 1.07 1 – 1.14 0.0464 976 8610 all phecode
362.27 Drusen (degenerative) of retina Sense Organs 1.04 0.946 – 1.14 0.434 488 4558 all phecode
362.29 Macular degeneration (senile) of retina NOS Sense Organs 1.03 0.981 – 1.08 0.24 1883 13955 all phecode
362.3 Other nondiabetic retinopathy Sense Organs 0.994 0.93 – 1.06 0.85 976 8527 all phecode
362.31 Separation of retinal layers Sense Organs 1.01 0.917 – 1.12 0.798 413 4056 all phecode
362.4 Retinal vascular changes and abnomalities Sense Organs 1 0.925 – 1.08 0.971 662 5933 all phecode
362.6 Peripheral retinal degenerations Sense Organs 1.04 0.941 – 1.15 0.433 392 3787 all phecode
362.7 Hereditary retinal dystrophies Sense Organs 1.02 0.889 – 1.18 0.748 215 2103 all phecode
362.8 Retinal hemorrhage/ischemia Sense Organs 0.874 0.767 – 0.995 0.0422 241 2368 all phecode
362.9 Retinal edema Sense Organs 0.966 0.86 – 1.08 0.551 324 2936 all phecode
363
Chorioretinal inflammations, scars, and other
Chorioretinal inflammations, scars, and other disorders of choroid
 Sense Organs 1.02 0.933 – 1.12 0.623 492 4746 all phecode
363.3 Chorioretinal scars Sense Organs 1.04 0.931 – 1.17 0.465 332 3184 all phecode
364 Corneal opacity and other disorders of cornea Sense Organs 1.04 0.979 – 1.11 0.198 1132 10772 all phecode
364.1 Corneal opacity Sense Organs 0.889 0.8 – 0.987 0.0274 394 3846 all phecode
364.2 Corneal edema Sense Organs 0.92 0.758 – 1.12 0.397 123 1208 all phecode
364.4 Corneal degenerations Sense Organs 0.966 0.871 – 1.07 0.508 402 3962 all phecode
364.41 Keratoconus Sense Organs 1.07 0.841 – 1.37 0.567 75 739 all phecode
364.5 Corneal dystrophy Sense Organs 1.15 1.05 – 1.26 0.00331 502 4682 all phecode
364.51 Fuchs' dystrophy Sense Organs 1.08 0.955 – 1.23 0.211 266 2521 all phecode
364.9 Cornea replaced by transplant Sense Organs 1.23 0.987 – 1.52 0.0649 91 885 all phecode
365 Glaucoma Sense Organs 1 0.965 – 1.05 0.835 2672 21326 all phecode
365.1 Open-angle glaucoma Sense Organs 1.01 0.931 – 1.09 0.891 705 6491 all phecode
365.11 Primary open angle glaucoma Sense Organs 1.04 0.941 – 1.16 0.424 403 3681 all phecode
365.2 Primary angle-closure glaucoma Sense Organs 1.08 0.945 – 1.23 0.266 251 2370 all phecode
366 Cataract Sense Organs 1.02 0.997 – 1.05 0.0808 8611 28043 all phecode
366.1 Nonsenile Cataract Sense Organs 1.06 0.912 – 1.22 0.469 207 1979 all phecode
366.2 Senile cataract Sense Organs 1.03 0.999 – 1.06 0.0603 5480 24980 all phecode
367
Disorders of refraction and accommodation
Disorders of refraction and accommodation; blindness and low vision
 Sense Organs 1.01 0.983 – 1.03 0.614 8967 37779 all phecode
367.1 Myopia Sense Organs 1.01 0.984 – 1.05 0.368 5014 34677 all phecode
367.2 Astigmatism Sense Organs 1.01 0.978 – 1.04 0.525 4161 32463 all phecode
367.8 Hypermetropia Sense Organs 1.03 0.979 – 1.07 0.281 2039 18599 all phecode
367.9 Blindness and low vision Sense Organs 0.941 0.889 – 0.997 0.0406 1277 12356 all phecode
368 Visual disturbances Sense Organs 1.01 0.987 – 1.04 0.299 5715 39599 all phecode
368.1 Amblyopia Sense Organs 1.03 0.946 – 1.11 0.527 651 6479 all phecode
368.2 Diplopia and disorders of binocular vision Sense Organs 0.95 0.893 – 1.01 0.107 1087 10786 all phecode
368.3 Anisometropia Sense Organs 0.863 0.753 – 0.989 0.0338 219 2168 all phecode
368.4 Visual field defects Sense Organs 0.977 0.92 – 1.04 0.46 1132 11173 all phecode
368.9 Subjective visual disturbances Sense Organs 0.99 0.93 – 1.05 0.764 1070 10620 all phecode
368.91 Psychophysical visual disturbances Sense Organs 0.9 0.749 – 1.08 0.26 120 1171 all phecode
369 Infection of the eye Sense Organs 0.999 0.963 – 1.04 0.974 3185 28240 all phecode
369.2 Eye infection, viral Sense Organs 0.973 0.886 – 1.07 0.574 502 4954 all phecode
369.5 Conjunctivitis, infectious Sense Organs 0.999 0.959 – 1.04 0.947 2716 24970 all phecode
370 Keratitis Sense Organs 0.967 0.914 – 1.02 0.239 1365 13169 all phecode
370.1 Corneal ulcer Sense Organs 1.08 0.941 – 1.25 0.26 223 2194 all phecode
370.2 Superficial keratitis Sense Organs 0.94 0.859 – 1.03 0.171 546 5393 all phecode
370.3 Keratoconjunctivitis Sense Organs 0.954 0.879 – 1.03 0.257 649 6263 all phecode
370.31 Keratoconjunctivitis sicca Sense Organs 1.02 0.879 – 1.19 0.764 179 1677 all phecode
371 Inflammation of the eye Sense Organs 1 0.969 – 1.03 0.996 4414 32310 all phecode
371.1 Uveitis, noninfectious or NOS Sense Organs 0.999 0.915 – 1.09 0.984 541 5278 all phecode
371.2 Conjunctivitis, noninfectious Sense Organs 0.986 0.921 – 1.06 0.696 906 8939 all phecode
371.21 Allergic conjunctivitis Sense Organs 1 0.932 – 1.08 0.909 756 7515 all phecode
371.3 Inflammation of eyelids Sense Organs 0.998 0.962 – 1.03 0.896 3398 26983 all phecode
371.33 Noninfectious dermatoses of eyelid Sense Organs 0.936 0.789 – 1.11 0.451 133 1291 all phecode
372 Disorders of conjunctiva Sense Organs 1.11 1.04 – 1.18 0.00209 1118 10728 all phecode
374 Other disorders of eyelids Sense Organs 1 0.965 – 1.04 0.897 2940 24188 all phecode
374.1 Ectropion or entropion Sense Organs 0.936 0.849 – 1.03 0.179 431 4084 all phecode
374.2 Lagophthalmos Sense Organs 0.91 0.796 – 1.04 0.164 235 2335 all phecode
374.3 Ptosis of eyelid Sense Organs 0.99 0.931 – 1.05 0.743 1102 10734 all phecode
374.6 Dermatochalasis Sense Organs 1 0.94 – 1.07 0.949 1040 9720 all phecode
375 Disorders of lacrimal system Sense Organs 0.973 0.94 – 1.01 0.132 3694 26045 all phecode
375.1 Dry eyes Sense Organs 0.999 0.965 – 1.03 0.941 4040 26751 all phecode
375.2 Epiphora Sense Organs 0.914 0.828 – 1.01 0.0749 442 4354 all phecode
376 Disorders of the orbit Sense Organs 1.04 0.933 – 1.16 0.463 352 3508 all phecode
377 Disorders of optic nerve and visual pathways Sense Organs 1.05 0.98 – 1.13 0.162 913 9021 all phecode
377.1 Optic atrophy Sense Organs 1.03 0.91 – 1.16 0.658 283 2793 all phecode
377.3 Optic neuritis/neuropathy Sense Organs 1.06 0.973 – 1.15 0.185 585 5775 all phecode
378
Strabismus and other disorders of binocular eye
Strabismus and other disorders of binocular eye movements
 Sense Organs 1 0.945 – 1.06 0.961 1275 12460 all phecode
378.1 Strabismus (not specified as paralytic) Sense Organs 0.991 0.923 – 1.06 0.812 828 8130 all phecode
378.2 Nystagmus and other irregular eye movements Sense Organs 1.02 0.873 – 1.2 0.78 170 1686 all phecode
378.5 Paralytic strabismus Sense Organs 0.954 0.856 – 1.06 0.403 349 3437 all phecode
379 Other disorders of eye Sense Organs 1.02 0.993 – 1.06 0.126 5046 29999 all phecode
379.1 Scleritis and episcleritis Sense Organs 0.918 0.784 – 1.08 0.292 176 1743 all phecode
379.2 Disorders of vitreous body Sense Organs 1.04 1 – 1.08 0.0366 3634 23186 all phecode
379.3 Aphakia and other disorders of lens Sense Organs 0.89 0.748 – 1.06 0.189 135 1258 all phecode
379.4 Anomalies of pupillary function Sense Organs 0.986 0.874 – 1.11 0.821 287 2833 all phecode
379.5 Disorders of iris and ciliary body Sense Organs 0.944 0.837 – 1.06 0.344 304 2948 all phecode
379.51 Pigmentary iris degeneration Sense Organs 1.04 0.823 – 1.32 0.735 77 731 all phecode
379.9 Pain, swelling or discharge of eye Sense Organs 0.962 0.905 – 1.02 0.217 1129 11130 all phecode
380 Disorders of external ear Sense Organs 1.03 0.983 – 1.07 0.237 2242 20393 all phecode
380.1 Otitis externa Sense Organs 0.999 0.947 – 1.05 0.98 1469 14580 all phecode
380.4 Impacted cerumen Sense Organs 1.03 0.992 – 1.08 0.12 2648 23557 all phecode
381 Otitis media and Eustachian tube disorders Sense Organs 0.991 0.96 – 1.02 0.596 4255 36417 all phecode
381.1 Otitis media Sense Organs 0.992 0.956 – 1.03 0.68 3079 29813 all phecode
381.11 Suppurative and unspecified otitis media Sense Organs 0.993 0.954 – 1.03 0.739 2610 25602 all phecode
381.2 Eustachian tube disorders Sense Organs 0.982 0.936 – 1.03 0.476 1816 17827 all phecode
381.3 Mastoiditis & related conditions Sense Organs 1.1 0.926 – 1.3 0.284 153 1530 all phecode
381.9 Otorrhea Sense Organs 0.963 0.864 – 1.07 0.489 372 3713 all phecode
382 Otalgia Sense Organs 0.993 0.947 – 1.04 0.772 1884 18673 all phecode
383 Otosclerosis Sense Organs 0.97 0.812 – 1.16 0.74 124 1240 all phecode
384 Other disorders of tympanic membrane Sense Organs 0.963 0.88 – 1.05 0.414 516 5156 all phecode
384.1 Myringitis Sense Organs 0.968 0.73 – 1.28 0.819 51 502 all phecode
384.4 Perforation of tympanic membrane Sense Organs 0.949 0.857 – 1.05 0.311 403 4029 all phecode
385 Other disorders of middle ear and mastoid Sense Organs 0.98 0.888 – 1.08 0.692 432 4320 all phecode
385.3 Cholesteatoma Sense Organs 0.97 0.858 – 1.1 0.624 277 2770 all phecode
385.5
Tympanosclerosis and middle ear disease related
Tympanosclerosis and middle ear disease related to otitis media
 Sense Organs 0.835 0.693 – 1.01 0.0574 118 1180 all phecode
386
Vertiginous syndromes and other disorders of
Vertiginous syndromes and other disorders of vestibular system
 Sense Organs 1.03 0.98 – 1.08 0.26 1882 18186 all phecode
386.1 Meniere's disease Sense Organs 1.02 0.909 – 1.15 0.732 319 3156 all phecode
386.2 Peripheral or central vertigo Sense Organs 1.04 0.988 – 1.1 0.128 1586 15423 all phecode
386.21 Central origin vertigo Sense Organs 1.07 1.01 – 1.14 0.0242 1208 11844 all phecode
386.3 Labyrinthitis Sense Organs 1.05 0.996 – 1.11 0.0695 1482 14530 all phecode
386.9
Dizziness and giddiness (Light-headedness and
Dizziness and giddiness (Light-headedness and vertigo)
 Sense Organs 1.02 0.992 – 1.05 0.166 6933 38286 all phecode
388 Other disorders of ear Sense Organs 1.02 0.957 – 1.09 0.498 960 9501 all phecode
389 Hearing loss Sense Organs 1 0.978 – 1.03 0.873 8182 38069 all phecode
389.1 Sensorineural hearing loss Sense Organs 0.993 0.961 – 1.03 0.692 4107 29258 all phecode
389.2 Conductive hearing loss Sense Organs 0.931 0.87 – 0.997 0.0403 905 9042 all phecode
389.3 Degenerative and vascular disorders of ear Sense Organs 0.93 0.801 – 1.08 0.341 192 1808 all phecode
389.4 Tinnitus Sense Organs 1.02 0.976 – 1.06 0.399 2291 22130 all phecode
389.5 Disorders of acoustic nerve Sense Organs 1.06 0.887 – 1.27 0.514 124 1229 all phecode
394 Rheumatic disease of the heart valves Circulatory System 1.02 0.97 – 1.08 0.388 1458 13732 all phecode
394.1 Mitral valve stenosis and aortic valve stenosis Circulatory System 1.01 0.907 – 1.13 0.81 350 3415 all phecode
394.2 Mitral valve disease Circulatory System 1.03 0.938 – 1.14 0.504 462 4560 all phecode
394.3 Aortic valve disease Circulatory System 1.05 0.895 – 1.22 0.567 176 1691 all phecode
394.4 Acute rheumatic heart disease Circulatory System 0.824 0.629 – 1.08 0.162 55 546 all phecode
394.7 Disease of tricuspid valve Circulatory System 1.04 0.959 – 1.14 0.318 587 5739 all phecode
395 Heart valve disorders Circulatory System 1.06 1.02 – 1.1 0.000886 3976 28748 all phecode
395.1 Nonrheumatic mitral valve disorders Circulatory System 1.05 1 – 1.1 0.039 2175 20441 all phecode
395.2 Nonrheumatic aortic valve disorders Circulatory System 1.08 1.03 – 1.13 0.00109 2060 17194 all phecode
395.3 Nonrheumatic tricuspid valve disorders Circulatory System 1.08 0.981 – 1.19 0.116 493 4864 all phecode
395.4 Nonrheumatic pulmonary valve disorders Circulatory System 1 0.824 – 1.23 0.961 108 1080 all phecode
395.6 Heart valve replaced Circulatory System 1.06 0.999 – 1.13 0.0533 1177 10833 all phecode
396 Abnormal heart sounds Circulatory System 1.04 1.01 – 1.07 0.0171 4718 34395 all phecode
401 Hypertension Circulatory System 1.02 0.998 – 1.04 0.0777 23317 23367 all phecode
401.1 Essential hypertension Circulatory System 1.02 0.998 – 1.04 0.0729 23158 23364 all phecode
401.2 Hypertensive heart and/or renal disease Circulatory System 1.02 0.976 – 1.06 0.442 3503 14616 all phecode
401.21 Hypertensive heart disease Circulatory System 1.13 1.05 – 1.21 0.000986 893 6607 all phecode
401.22 Hypertensive chronic kidney disease Circulatory System 0.995 0.952 – 1.04 0.82 2584 13072 all phecode
401.3 Other hypertensive complications Circulatory System 1.06 1.02 – 1.11 0.00678 2679 15833 all phecode
411 Ischemic Heart Disease Circulatory System 1.11 1.08 – 1.14 1.33e-15 8807 30299 all phecode
411.1 Unstable angina (intermediate coronary syndrome) Circulatory System 1.23 1.15 – 1.32 4.55e-09 937 8574 all phecode
411.2 Myocardial infarction Circulatory System 1.12 1.08 – 1.16 9.34e-10 3594 21716 all phecode
411.3 Angina pectoris Circulatory System 1.14 1.09 – 1.19 2.91e-09 2485 18304 all phecode
411.4 Coronary atherosclerosis Circulatory System 1.12 1.09 – 1.15 9.9e-17 7555 27492 all phecode
411.41 Aneurysm and dissection of heart Circulatory System 1.19 0.997 – 1.41 0.0542 156 1529 all phecode
411.8
Other chronic ischemic heart disease
Other chronic ischemic heart disease, unspecified
 Circulatory System 1.13 1.1 – 1.17 6.26e-17 6331 25741 all phecode
411.9
Other acute and subacute forms of ischemic
Other acute and subacute forms of ischemic heart disease
 Circulatory System 1.07 0.973 – 1.19 0.156 442 4211 all phecode
414 Other forms of chronic heart disease Circulatory System 1.13 1.09 – 1.18 1.73e-10 3101 22616 all phecode
414.2 ASCVD Circulatory System 1.14 1.06 – 1.24 0.000823 718 6816 all phecode
415 Pulmonary heart disease Circulatory System 1.01 0.974 – 1.05 0.611 3366 30208 all phecode
415.1 Acute pulmonary heart disease Circulatory System 1.01 0.966 – 1.06 0.611 1912 19014 all phecode
415.11 Pulmonary embolism and infarction, acute Circulatory System 1.01 0.964 – 1.06 0.657 1906 18953 all phecode
415.2 Chronic pulmonary heart disease Circulatory System 1.01 0.965 – 1.06 0.606 1808 17605 all phecode
415.21 Primary pulmonary hypertension Circulatory System 1.02 0.944 – 1.11 0.597 706 7032 all phecode
416 Cardiomegaly Circulatory System 0.947 0.894 – 1 0.0662 1254 12372 all phecode
418 Nonspecific chest pain Circulatory System 1.02 1 – 1.05 0.0209 12650 33952 all phecode
418.1 Precordial pain Circulatory System 1.09 1.03 – 1.15 0.00337 1471 13782 all phecode
420 Carditis Circulatory System 1.04 0.991 – 1.1 0.105 1588 15680 all phecode
420.1 Myocarditis Circulatory System 1.01 0.818 – 1.24 0.933 97 958 all phecode
420.2 Pericarditis Circulatory System 1.01 0.94 – 1.08 0.801 842 8402 all phecode
420.21 Acute pericarditis Circulatory System 0.947 0.813 – 1.1 0.482 177 1764 all phecode
420.22 Chronic pericarditis Circulatory System 1.03 0.854 – 1.25 0.736 117 1153 all phecode
420.3 Endocarditis Circulatory System 1.03 0.953 – 1.11 0.489 764 7535 all phecode
425 Cardiomyopathy Circulatory System 1.05 1.01 – 1.1 0.0222 2078 19881 all phecode
425.1 Primary/intrinsic cardiomyopathies Circulatory System 1.05 1 – 1.1 0.0343 1989 19025 all phecode
425.11 Hypertrophic obstructive cardiomyopathy Circulatory System 1.01 0.877 – 1.16 0.892 208 2050 all phecode
425.12 Other hypertrophic cardiomyopathy Circulatory System 1.1 0.949 – 1.27 0.206 201 1992 all phecode
425.2 Secondary/extrinsic cardiomyopathies Circulatory System 0.962 0.86 – 1.08 0.501 317 3170 all phecode
425.8 Other cardiomyopathy Circulatory System 0.948 0.768 – 1.17 0.621 95 931 all phecode
426 Cardiac conduction disorders Circulatory System 1.02 1 – 1.05 0.0433 12327 25440 all phecode
426.2 Atrioventricular [AV] block Circulatory System 1.06 1.01 – 1.11 0.0248 1903 11501 all phecode
426.21 First degree AV block Circulatory System 1.05 0.992 – 1.12 0.0875 1313 8899 all phecode
426.22 Mobitz II AV block Circulatory System 1.2 0.93 – 1.54 0.164 64 553 all phecode
426.23 Second degree AV block Circulatory System 1.08 0.943 – 1.25 0.255 216 1925 all phecode
426.24 Atrioventricular block, complete Circulatory System 1.11 1 – 1.22 0.0426 461 3823 all phecode
426.25 Other heart block Circulatory System 1.04 0.896 – 1.21 0.603 203 1803 all phecode
426.3 Bundle branch block Circulatory System 1.05 1.01 – 1.1 0.0294 2306 13999 all phecode
426.31 Right bundle branch block Circulatory System 1.04 0.979 – 1.1 0.216 1423 10758 all phecode
426.32 Left bundle branch block Circulatory System 1.04 0.973 – 1.11 0.24 969 8110 all phecode
426.4 Anomalous atrioventricular excitation Circulatory System 1.01 0.805 – 1.28 0.908 82 820 all phecode
426.7 Abnormal electrocardiogram [ECG] [EKG] Circulatory System 1.02 1 – 1.05 0.0485 10577 25186 all phecode
426.8 Other cardiac conduction disorders Circulatory System 0.975 0.902 – 1.05 0.53 679 6650 all phecode
426.9 Cardiac pacemaker/device in situ Circulatory System 1.04 0.991 – 1.1 0.105 1754 11536 all phecode
426.91 Cardiac pacemaker in situ Circulatory System 1.03 0.968 – 1.1 0.352 1171 8184 all phecode
426.92 Cardiac defibrillator in situ Circulatory System 1.07 0.999 – 1.15 0.0525 846 7320 all phecode
427 Cardiac dysrhythmias Circulatory System 1 0.984 – 1.02 0.712 17397 25735 all phecode
427.1 Paroxysmal tachycardia, unspecified Circulatory System 1.04 0.998 – 1.09 0.0635 2474 18178 all phecode
427.11 Paroxysmal supraventricular tachycardia Circulatory System 1.04 0.984 – 1.09 0.173 1595 14293 all phecode
427.12 Paroxysmal ventricular tachycardia Circulatory System 1.07 1 – 1.13 0.04 1181 9915 all phecode
427.2 Atrial fibrillation and flutter Circulatory System 1.01 0.982 – 1.05 0.395 5313 18688 all phecode
427.21 Atrial fibrillation Circulatory System 1.02 0.983 – 1.05 0.353 5188 18409 all phecode
427.22 Atrial flutter Circulatory System 1.03 0.978 – 1.09 0.262 1693 11042 all phecode
427.3 Other specified cardiac dysrhythmias Circulatory System 1.01 0.988 – 1.04 0.302 8688 25552 all phecode
427.4 Cardiac arrest and ventricular fibrillation Circulatory System 1.01 0.919 – 1.1 0.907 536 5233 all phecode
427.41 Ventricular fibrillation and flutter Circulatory System 1.14 0.99 – 1.32 0.0675 216 2118 all phecode
427.42 Cardiac arrest Circulatory System 0.982 0.886 – 1.09 0.723 410 4034 all phecode
427.5 Arrhythmia (cardiac) NOS Circulatory System 1.01 0.981 – 1.04 0.531 6905 25457 all phecode
427.6 Premature beats Circulatory System 1.06 1.02 – 1.11 0.00698 2359 16248 all phecode
427.61 Supraventricular premature beats Circulatory System 1.03 0.948 – 1.11 0.507 670 6287 all phecode
427.7 Tachycardia NOS Circulatory System 1.01 0.981 – 1.04 0.485 5124 25531 all phecode
427.8 Sinoatrial node dysfunction (Bradycardia) Circulatory System 1.04 0.966 – 1.11 0.325 912 7501 all phecode
427.9 Palpitations Circulatory System 1.02 0.983 – 1.05 0.351 4430 24505 all phecode
428 Congestive heart failure; nonhypertensive Circulatory System 1.05 1.01 – 1.08 0.00478 4300 23663 all phecode
428.1 Congestive heart failure (CHF) NOS Circulatory System 1.05 1.01 – 1.09 0.00933 3756 22446 all phecode
428.2 Heart failure NOS Circulatory System 1.04 1.01 – 1.08 0.0198 3701 21722 all phecode
428.3
Heart failure with reduced EF [Systolic or
Heart failure with reduced EF [Systolic or combined heart failure]
 Circulatory System 1.07 1.02 – 1.12 0.0103 1765 14476 all phecode
428.4
Heart failure with preserved EF [Diastolic
Heart failure with preserved EF [Diastolic heart failure]
 Circulatory System 1.01 0.963 – 1.07 0.593 1648 13395 all phecode
429
Ill-defined descriptions and complications of
Ill-defined descriptions and complications of heart disease
 Circulatory System 1.03 1.01 – 1.05 0.00459 12635 32504 all phecode
429.1 Heart transplant/surgery Circulatory System 1.09 1.03 – 1.16 0.00428 1219 11696 all phecode
429.2 Abnormal function study of cardiovascular system Circulatory System 1.05 1.02 – 1.08 0.000726 6322 29232 all phecode
429.3 Symptoms involving cardiovascular system Circulatory System 1.03 1 – 1.05 0.0223 9650 32421 all phecode
429.9 Cardiac complications, not elsewhere classified Circulatory System 1.05 0.974 – 1.14 0.198 723 7072 all phecode
430 Intracranial hemorrhage Circulatory System 0.958 0.891 – 1.03 0.246 789 7842 all phecode
430.1 Subarachnoid hemorrhage Circulatory System 0.953 0.84 – 1.08 0.451 261 2610 all phecode
430.2 Intracerebral hemorrhage Circulatory System 0.927 0.834 – 1.03 0.155 368 3671 all phecode
430.3 Subdural hemorrhage Circulatory System 0.956 0.845 – 1.08 0.469 272 2680 all phecode
433 Cerebrovascular disease Circulatory System 1.04 1.01 – 1.07 0.0184 5463 32242 all phecode
433.1 Occlusion and stenosis of precerebral arteries Circulatory System 1.08 1.03 – 1.13 0.00107 1978 16212 all phecode
433.11
Occlusion of cerebral arteries, with cerebral
Occlusion of cerebral arteries, with cerebral infarction
 Circulatory System 1.12 0.987 – 1.27 0.0791 260 2517 all phecode
433.12 Cerebral atherosclerosis Circulatory System 1.12 0.892 – 1.4 0.335 80 789 all phecode
433.2 Occlusion of cerebral arteries Circulatory System 1.01 0.97 – 1.05 0.603 2437 21732 all phecode
433.21
Cerebral artery occlusion, with cerebral
Cerebral artery occlusion, with cerebral infarction
 Circulatory System 1.01 0.971 – 1.06 0.548 2357 21103 all phecode
433.3 Cerebral ischemia Circulatory System 1.02 0.982 – 1.06 0.301 2780 22868 all phecode
433.31 Transient cerebral ischemia Circulatory System 1.01 0.972 – 1.06 0.513 2409 20762 all phecode
433.5 Cerebral aneurysm Circulatory System 1.05 0.959 – 1.16 0.281 474 4724 all phecode
433.6 Acute, but ill-defined cerebrovascular disease Circulatory System 1.01 0.92 – 1.11 0.806 464 4518 all phecode
433.8 Late effects of cerebrovascular disease Circulatory System 1.01 0.934 – 1.09 0.792 695 6822 all phecode
440 Atherosclerosis Circulatory System 1.07 1.03 – 1.12 8e-04 2477 19724 all phecode
440.1 Atherosclerosis of renal artery Circulatory System 1.12 0.977 – 1.28 0.104 231 2291 all phecode
440.2 Atherosclerosis of the extremities Circulatory System 1.04 0.987 – 1.1 0.138 1516 13532 all phecode
440.21
Atherosclerosis of native arteries of the
Atherosclerosis of native arteries of the extremities with ulceration or gangrene
 Circulatory System 1.08 0.954 – 1.22 0.225 274 2669 all phecode
440.22
Atherosclerosis of native arteries of the
Atherosclerosis of native arteries of the extremities with intermittent claudication
 Circulatory System 1.05 0.983 – 1.12 0.155 1040 9647 all phecode
440.9 Atherosclerosis of aorta Circulatory System 1.11 1.03 – 1.19 0.00432 846 8124 all phecode
441 Vascular insufficiency of intestine Circulatory System 0.972 0.888 – 1.06 0.543 515 5115 all phecode
441.1 Acute vascular insufficiency of intestine Circulatory System 1.01 0.881 – 1.16 0.901 240 2387 all phecode
441.2 Chronic vascular insufficiency of intestine Circulatory System 1.1 0.931 – 1.3 0.261 154 1536 all phecode
442 Other aneurysm Circulatory System 1.04 0.996 – 1.08 0.0791 2779 21466 all phecode
442.1 Aortic aneurysm Circulatory System 1.05 1.01 – 1.1 0.0283 2054 16492 all phecode
442.11 Abdominal aortic aneurysm Circulatory System 1.1 1.04 – 1.17 0.0019 1189 10558 all phecode
442.2 Aneurysm of iliac artery Circulatory System 1.11 0.961 – 1.29 0.154 202 2002 all phecode
442.3 Aneurysm of artery of lower extremity Circulatory System 1.02 0.871 – 1.18 0.843 179 1765 all phecode
442.4 Arterial dissection Circulatory System 0.979 0.843 – 1.14 0.781 184 1840 all phecode
442.8 Aneurysm of other specified artery Circulatory System 1.02 0.919 – 1.13 0.726 399 3978 all phecode
443 Peripheral vascular disease Circulatory System 1.04 1 – 1.08 0.0266 3086 24814 all phecode
443.1 Raynaud's syndrome Circulatory System 0.981 0.91 – 1.06 0.621 742 7390 all phecode
443.7
Peripheral angiopathy in diseases classified
Peripheral angiopathy in diseases classified elsewhere
 Circulatory System 1.11 0.965 – 1.27 0.146 220 2087 all phecode
443.8 Other specified peripheral vascular diseases Circulatory System 1.04 0.995 – 1.08 0.0874 2557 21985 all phecode
443.9 Peripheral vascular disease, unspecified Circulatory System 1.05 1.01 – 1.1 0.0164 2341 18862 all phecode
444 Arterial embolism and thrombosis Circulatory System 1.02 0.947 – 1.09 0.662 848 8423 all phecode
444.1
Arterial embolism and thrombosis of lower
Arterial embolism and thrombosis of lower extremity artery
 Circulatory System 0.997 0.887 – 1.12 0.957 313 3099 all phecode
444.2 Embolism and thrombosis of abdominal aorta Circulatory System 1.16 0.982 – 1.38 0.0807 155 1548 all phecode
446 Polyarteritis nodosa and allied conditions Circulatory System 1.05 0.951 – 1.15 0.356 460 4559 all phecode
446.4 Wegener's granulomatosis Circulatory System 1.12 0.92 – 1.36 0.259 109 1075 all phecode
446.5 Giant cell arteritis Circulatory System 1.1 0.881 – 1.38 0.395 79 749 all phecode
446.9 Arteritis NOS Circulatory System 0.98 0.87 – 1.11 0.746 289 2876 all phecode
447 Other disorders of arteries and arterioles Circulatory System 1.05 1.01 – 1.09 0.0217 2647 22765 all phecode
447.1 Stricture of artery Circulatory System 1.07 0.976 – 1.17 0.156 523 5163 all phecode
447.7 Aortic ectasia Circulatory System 1 0.935 – 1.08 0.894 804 7938 all phecode
448 Disease of capillaries Circulatory System 0.996 0.939 – 1.06 0.886 1237 12127 all phecode
450 Noninfectious disorders of lymphatic channels Circulatory System 0.955 0.913 – 0.999 0.0446 2104 20985 all phecode
451 Phlebitis and thrombophlebitis Circulatory System 0.959 0.888 – 1.03 0.277 738 7355 all phecode
451.2
Phlebitis and thrombophlebitis of lower
Phlebitis and thrombophlebitis of lower extremities
 Circulatory System 0.947 0.83 – 1.08 0.414 244 2437 all phecode
452 Other venous embolism and thrombosis Circulatory System 0.982 0.953 – 1.01 0.243 4957 29867 all phecode
452.1 Iatrogenic pulmonary embolism and infarction Circulatory System 1 0.884 – 1.14 0.964 276 2747 all phecode
452.2 Deep vein thrombosis [DVT] Circulatory System 0.966 0.931 – 1 0.0621 3260 26940 all phecode
452.8 Postphlebitic syndrome Circulatory System 1.05 0.891 – 1.24 0.543 154 1529 all phecode
453 Chronic venous hypertension Circulatory System 0.975 0.85 – 1.12 0.714 220 2168 all phecode
454 Varicose veins Circulatory System 0.951 0.914 – 0.989 0.0118 2827 24555 all phecode
454.1 Varicose veins of lower extremity Circulatory System 0.952 0.913 – 0.993 0.0211 2469 21426 all phecode
454.11 Varicose veins of lower extremity, symptomtic Circulatory System 0.943 0.895 – 0.994 0.0277 1565 15056 all phecode
455 Hemorrhoids Circulatory System 1.05 1.02 – 1.08 0.00187 5799 29818 all phecode
456 Chronic venous insufficiency [CVI] Circulatory System 0.959 0.924 – 0.996 0.0303 3097 24898 all phecode
457
Encounter for long-term (current) use of
Encounter for long-term (current) use of anticoagulants, antithrombotics, aspirin
 Circulatory System 1.06 1.01 – 1.11 0.0176 2095 15309 all phecode
457.2
Encounter for long-term (current) use of
Encounter for long-term (current) use of antiplatelets/antithrombotics
 Circulatory System 1.12 0.996 – 1.25 0.0592 324 3221 all phecode
457.3 Encounter for long-term (current) use of aspirin Circulatory System 1.06 1.01 – 1.11 0.0221 1973 14689 all phecode
458 Hypotension Circulatory System 1.01 0.984 – 1.04 0.366 5091 32185 all phecode
458.1 Orthostatic hypotension Circulatory System 0.968 0.914 – 1.02 0.255 1344 12938 all phecode
458.2 Iatrogenic hypotension Circulatory System 1.01 0.946 – 1.07 0.825 1109 11012 all phecode
458.9 Hypotension NOS Circulatory System 1.02 0.984 – 1.05 0.328 4618 31186 all phecode
459 Other disorders of circulatory system Circulatory System 1.02 0.991 – 1.04 0.217 7825 34792 all phecode
459.1 Hemorrhage NOS Circulatory System 1.01 0.937 – 1.08 0.85 834 8215 all phecode
459.7 Blood vessel replaced Circulatory System 1 0.947 – 1.06 0.92 1305 13023 all phecode
459.9 Circulatory disease NEC Circulatory System 1.02 0.993 – 1.05 0.156 6706 33592 all phecode
464 Acute sinusitis Respiratory 0.994 0.964 – 1.03 0.705 4792 32137 all phecode
465
Acute upper respiratory infections of multiple
Acute upper respiratory infections of multiple or unspecified sites
 Respiratory 1.01 0.982 – 1.03 0.653 9601 35915 all phecode
465.2 Acute pharyngitis Respiratory 1 0.975 – 1.03 0.759 5310 32365 all phecode
465.4 Acute laryngitis and tracheitis Respiratory 1.05 0.954 – 1.16 0.301 443 4428 all phecode
470 Septal Deviations/Turbinate Hypertrophy Respiratory 0.967 0.921 – 1.02 0.184 1797 17640 all phecode
471 Nasal polyps Respiratory 0.991 0.911 – 1.08 0.837 592 5881 all phecode
472 Chronic pharyngitis and nasopharyngitis Respiratory 0.97 0.924 – 1.02 0.228 1797 16986 all phecode
473 Diseases of the larynx and vocal cords Respiratory 0.985 0.948 – 1.02 0.44 2983 25244 all phecode
473.1 Chronic laryngitis Respiratory 0.921 0.726 – 1.17 0.497 68 674 all phecode
473.3 Paralysis/spasm of vocal cords or larynx Respiratory 1.04 0.955 – 1.12 0.396 628 6254 all phecode
473.4 Voice disturbance Respiratory 0.999 0.957 – 1.04 0.973 2336 21975 all phecode
474 Acute and chronic tonsillitis Respiratory 1.02 0.949 – 1.09 0.617 880 7892 all phecode
474.1 Acute tonsillitis Respiratory 1.01 0.904 – 1.14 0.818 335 3181 all phecode
474.2 Chronic tonsillitis and adenoiditis Respiratory 1.03 0.956 – 1.12 0.395 700 6445 all phecode
475 Chronic sinusitis Respiratory 0.99 0.958 – 1.02 0.522 4378 27891 all phecode
475.9 Postnasal drip Respiratory 1.01 0.944 – 1.08 0.769 922 9017 all phecode
476 Allergic rhinitis Respiratory 0.992 0.971 – 1.01 0.433 12687 28117 all phecode
477 Epistaxis or throat hemorrhage Respiratory 1.09 1.02 – 1.16 0.0073 1150 11318 all phecode
478 Throat pain Respiratory 1.08 0.976 – 1.2 0.136 426 4195 all phecode
479 Other upper respiratory disease Respiratory 0.997 0.968 – 1.03 0.834 5627 28048 all phecode
480 Pneumonia Respiratory 1.03 1 – 1.06 0.0216 5947 37034 all phecode
480.1 Bacterial pneumonia Respiratory 1.04 0.975 – 1.1 0.255 1155 11495 all phecode
480.11 Pneumococcal pneumonia Respiratory 1.04 0.957 – 1.14 0.327 568 5644 all phecode
480.12 Pseudomonal pneumonia Respiratory 1.11 0.941 – 1.31 0.218 153 1523 all phecode
480.13 MRSA pneumonia Respiratory 0.832 0.684 – 1.01 0.0662 117 1165 all phecode
480.2 Viral pneumonia Respiratory 1.07 0.927 – 1.23 0.37 202 1992 all phecode
480.3 Pneumonia due to fungus (mycoses) Respiratory 1.06 0.901 – 1.24 0.502 159 1590 all phecode
480.5 Bronchopneumonia and lung abscess Respiratory 0.987 0.828 – 1.18 0.884 135 1312 all phecode
481 Influenza Respiratory 0.995 0.941 – 1.05 0.869 1355 13284 all phecode
483 Acute bronchitis and bronchiolitis Respiratory 1 0.97 – 1.04 0.788 3412 29871 all phecode
495 Asthma Respiratory 0.989 0.965 – 1.01 0.346 8671 33569 all phecode
495.1 Chronic obstructive asthma Respiratory 1.02 0.919 – 1.13 0.719 397 3925 all phecode
495.11 Chronic obstructive asthma with exacerbation Respiratory 1.16 0.918 – 1.46 0.215 81 802 all phecode
495.2 Asthma with exacerbation Respiratory 0.997 0.948 – 1.05 0.923 1629 16033 all phecode
496 Chronic airway obstruction Respiratory 1 0.97 – 1.03 0.976 5343 28343 all phecode
496.1 Emphysema Respiratory 1.02 0.98 – 1.07 0.28 2134 19414 all phecode
496.2 Chronic bronchitis Respiratory 0.991 0.959 – 1.02 0.581 4128 26624 all phecode
496.21 Obstructive chronic bronchitis Respiratory 0.998 0.964 – 1.03 0.901 3747 25467 all phecode
496.3 Bronchiectasis Respiratory 1.07 0.98 – 1.17 0.13 549 5453 all phecode
497 Bronchitis Respiratory 1 0.958 – 1.05 0.841 1946 18824 all phecode
498 Acute bronchospasm Respiratory 0.973 0.887 – 1.07 0.555 496 4943 all phecode
499 Cystic fibrosis Respiratory 0.927 0.783 – 1.1 0.382 151 1510 all phecode
500 Lung disease due to external agents Respiratory 0.911 0.835 – 0.993 0.0344 557 5551 all phecode
500.1 Extrinsic allergic alveolitis Respiratory 0.944 0.764 – 1.17 0.597 92 920 all phecode
500.2 Pneumoconiosis Respiratory 0.887 0.719 – 1.09 0.265 78 764 all phecode
501 Pneumonitis due to inhalation of food or vomitus Respiratory 1.05 0.965 – 1.14 0.261 634 6225 all phecode
502 Postinflammatory pulmonary fibrosis Respiratory 0.995 0.926 – 1.07 0.899 815 8076 all phecode
503 Pulmonary congestion and hypostasis Respiratory 1.02 0.954 – 1.1 0.5 835 8243 all phecode
504 Other alveolar and parietoalveolar pneumonopathy Respiratory 0.978 0.899 – 1.06 0.61 595 5878 all phecode
504.1 Idiopathic fibrosing alveolitis Respiratory 1.06 0.943 – 1.19 0.327 311 3084 all phecode
505 Other pulmonary inflamation or edema Respiratory 1.03 0.978 – 1.08 0.265 1638 15749 all phecode
506 Empyema and pneumothorax Respiratory 1.05 1.01 – 1.09 0.0217 2894 25235 all phecode
507 Pleurisy; pleural effusion Respiratory 1.01 0.971 – 1.05 0.633 2916 26208 all phecode
508
Pulmonary collapse; interstitial and
Pulmonary collapse; interstitial and compensatory emphysema
 Respiratory 1.01 0.97 – 1.06 0.581 2382 22588 all phecode
509 Respiratory failure, insufficiency, arrest Respiratory 1.03 0.994 – 1.06 0.114 4032 29477 all phecode
509.1 Respiratory failure Respiratory 1 0.959 – 1.05 0.846 1937 18949 all phecode
509.2 Respiratory insufficiency Respiratory 1.02 0.961 – 1.08 0.501 1174 11679 all phecode
509.3
Pulmonary insufficiency or respiratory failure
Pulmonary insufficiency or respiratory failure following trauma and surgery
 Respiratory 1.02 0.972 – 1.07 0.403 1689 16489 all phecode
509.8
Dependence on respirator [Ventilator] or
Dependence on respirator [Ventilator] or supplemental oxygen
 Respiratory 1.04 0.988 – 1.09 0.14 1741 17249 all phecode
510 Other diseases of lung Respiratory 1 0.976 – 1.03 0.765 5503 35907 all phecode
510.2 Lung transplant Respiratory 1.13 0.974 – 1.32 0.104 176 1757 all phecode
512 Other symptoms of respiratory system Respiratory 1.01 0.993 – 1.03 0.235 18621 28154 all phecode
512.1 Wheezing Respiratory 0.984 0.93 – 1.04 0.568 1409 13516 all phecode
512.2 Painful respiration Respiratory 1 0.962 – 1.05 0.843 2309 21263 all phecode
512.3 Abnormal chest sounds Respiratory 1.03 0.911 – 1.16 0.637 291 2845 all phecode
512.7 Shortness of breath Respiratory 1.02 0.999 – 1.05 0.0596 10034 28081 all phecode
512.8 Cough Respiratory 0.998 0.974 – 1.02 0.856 9501 28148 all phecode
512.9 Other dyspnea Respiratory 1.02 0.998 – 1.04 0.0694 10804 28104 all phecode
513 Respiratory abnormalities Respiratory 1.01 0.989 – 1.03 0.356 12932 33822 all phecode
513.3 Hypoventilation Respiratory 0.961 0.896 – 1.03 0.261 880 8646 all phecode
513.31 Apnea Respiratory 1.02 0.926 – 1.12 0.688 462 4607 all phecode
513.32 Orthopnea Respiratory 0.912 0.796 – 1.05 0.185 220 2160 all phecode
513.4 Hyperventilation Respiratory 1.03 0.94 – 1.13 0.538 515 5124 all phecode
513.8 Disorders of diaphragm Respiratory 1 0.881 – 1.14 0.985 258 2557 all phecode
514 Abnormal findings examination of lungs Respiratory 0.994 0.966 – 1.02 0.685 5365 34834 all phecode
514.1
Abnormal results of function study of pulmonary
Abnormal results of function study of pulmonary system
 Respiratory 0.99 0.873 – 1.12 0.877 258 2580 all phecode
514.2 Solitary pulmonary nodule Respiratory 0.995 0.959 – 1.03 0.812 3018 27338 all phecode
516 Abnormal sputum Respiratory 0.973 0.901 – 1.05 0.473 735 7332 all phecode
516.1 Hemoptysis Respiratory 0.97 0.893 – 1.05 0.476 611 6080 all phecode
519
Other diseases of respiratory system, not
Other diseases of respiratory system, not elsewhere classified
 Respiratory 1.02 0.99 – 1.04 0.23 6458 39057 all phecode
519.1 Tracheostomy complications Respiratory 1.01 0.878 – 1.17 0.865 214 2136 all phecode
519.2 Respiratory complications Respiratory 0.993 0.901 – 1.1 0.895 445 4430 all phecode
519.8 Other diseases of respiratory system, NEC Respiratory 0.997 0.946 – 1.05 0.914 1588 15787 all phecode
519.9
Symptoms involving respiratory system and other
Symptoms involving respiratory system and other chest symptoms
 Respiratory 1.02 0.992 – 1.05 0.152 4706 34489 all phecode
520 Disorders of tooth development Digestive 1.03 0.927 – 1.15 0.561 369 3690 all phecode
520.1 Hereditary disturbances in tooth structure Digestive 1.03 0.876 – 1.21 0.731 165 1642 all phecode
520.2 Disturbances in tooth eruption Digestive 1.02 0.887 – 1.17 0.776 218 2172 all phecode
521 Diseases of hard tissues of teeth Digestive 0.957 0.893 – 1.02 0.204 898 8954 all phecode
521.1 Dental caries Digestive 0.951 0.886 – 1.02 0.163 837 8349 all phecode
521.2 Dental abrasion, erosion and attrition Digestive 0.956 0.722 – 1.27 0.752 52 510 all phecode
522 Diseases of pulp and periapical tissues Digestive 1.05 0.963 – 1.15 0.257 535 5340 all phecode
522.5 Periapical abscess Digestive 1.03 0.935 – 1.13 0.561 459 4583 all phecode
523 Gingival and periodontal diseases Digestive 1 0.93 – 1.08 0.922 718 7180 all phecode
523.1 Gingivitis Digestive 0.824 0.695 – 0.978 0.0264 142 1418 all phecode
523.3 Periodontitis (acute or chronic) Digestive 1.03 0.929 – 1.15 0.557 364 3636 all phecode
523.31 Acute periodontitis Digestive 0.998 0.891 – 1.12 0.978 311 3109 all phecode
523.32 Chronic periodontitis Digestive 1.1 0.916 – 1.32 0.307 122 1204 all phecode
524 Dentofacial anomalies, including malocclusion Digestive 1.04 0.933 – 1.16 0.482 363 3630 all phecode
524.3 Anomalies of tooth position/malocclusion Digestive 1.09 0.945 – 1.25 0.241 220 2200 all phecode
525
Other diseases of the teeth and supporting
Other diseases of the teeth and supporting structures
 Digestive 1.01 0.947 – 1.08 0.75 1039 10382 all phecode
525.1 Loss of teeth or edentulism Digestive 0.966 0.868 – 1.07 0.524 374 3731 all phecode
526 Diseases of the jaws Digestive 0.994 0.955 – 1.03 0.776 2680 26455 all phecode
526.1 Cysts of the jaws Digestive 0.98 0.857 – 1.12 0.77 247 2470 all phecode
526.3 Anomalies of jaw size/symmetry Digestive 0.975 0.856 – 1.11 0.705 241 2383 all phecode
526.4 Temporomandibular joint disorders Digestive 0.997 0.945 – 1.05 0.908 1504 15025 all phecode
526.41 Temporomandibular joint disorder, unspecified Digestive 0.999 0.941 – 1.06 0.971 1187 11858 all phecode
526.42 Arthralgia/ankylosis of temporomandibular joint Digestive 1.02 0.944 – 1.1 0.636 741 7400 all phecode
526.5 Inflammatory conditions of jaw Digestive 1.01 0.89 – 1.13 0.933 287 2864 all phecode
526.8 Exostosis of jaw Digestive 1.1 0.831 – 1.46 0.502 53 521 all phecode
526.9 Jaw disease NOS Digestive 0.957 0.871 – 1.05 0.354 487 4867 all phecode
527 Diseases of the salivary glands Digestive 0.99 0.943 – 1.04 0.684 1781 17771 all phecode
527.1 Hypertrophy of salivary gland Digestive 0.992 0.764 – 1.29 0.952 58 579 all phecode
527.2 Sialoadenitis Digestive 1.06 0.954 – 1.17 0.286 394 3936 all phecode
527.7 Disturbance of salivary secretion Digestive 1.01 0.946 – 1.08 0.751 952 9481 all phecode
527.8 Other specified diseases of the salivary glands Digestive 0.99 0.872 – 1.12 0.881 254 2540 all phecode
528
Diseases of the oral soft tissues, excluding
Diseases of the oral soft tissues, excluding lesions specific for gingiva and tongue
 Digestive 0.983 0.945 – 1.02 0.411 2643 26197 all phecode
528.1 Stomatitis and mucositis Digestive 0.936 0.865 – 1.01 0.0996 668 6657 all phecode
528.11 Stomatitis and mucositis (ulcerative) Digestive 0.863 0.753 – 0.988 0.0334 211 2110 all phecode
528.12 Oral aphthae Digestive 0.93 0.811 – 1.07 0.304 215 2137 all phecode
528.3 Cellulitis and abscess of oral soft tissues Digestive 0.987 0.862 – 1.13 0.843 235 2338 all phecode
528.4 Cysts of oral soft tissues Digestive 1.07 0.894 – 1.29 0.446 124 1229 all phecode
528.41 Cyst of the salivary gland Digestive 1.02 0.814 – 1.28 0.861 77 760 all phecode
528.5 Diseases of lips Digestive 1 0.908 – 1.1 1 462 4602 all phecode
528.6 Leukoplakia of oral mucosa Digestive 0.908 0.764 – 1.08 0.272 137 1370 all phecode
528.7 Sialolithiasis Digestive 1.11 0.945 – 1.3 0.205 163 1623 all phecode
529 Diseases and other conditions of the tongue Digestive 1 0.927 – 1.08 0.96 690 6878 all phecode
529.1 Glossitis Digestive 0.97 0.813 – 1.16 0.736 129 1281 all phecode
529.6 Glossodynia Digestive 0.898 0.767 – 1.05 0.179 168 1652 all phecode
530 Diseases of esophagus Digestive 0.986 0.967 – 1.01 0.166 17081 27931 all phecode
530.1 Esophagitis, GERD and related diseases Digestive 0.986 0.967 – 1.01 0.162 16572 27931 all phecode
530.11 GERD Digestive 0.984 0.965 – 1 0.117 16143 27929 all phecode
530.12 Ulcer of esophagus Digestive 1.04 0.934 – 1.16 0.479 400 3983 all phecode
530.13 Barrett's esophagus Digestive 0.973 0.903 – 1.05 0.478 762 7584 all phecode
530.14 Reflux esophagitis Digestive 0.973 0.927 – 1.02 0.257 1900 17495 all phecode
530.15 Eosinophilic esophagitis Digestive 0.794 0.691 – 0.912 0.00109 221 2210 all phecode
530.2 Esophageal bleeding (varices/hemorrhage) Digestive 0.949 0.875 – 1.03 0.206 651 6473 all phecode
530.3 Stricture and stenosis of esophagus Digestive 1.01 0.945 – 1.09 0.719 911 8971 all phecode
530.5 Disorders of esophageal motility Digestive 1.02 0.934 – 1.11 0.65 548 5432 all phecode
530.6 Diverticulum of esophagus, acquired Digestive 1.14 0.947 – 1.37 0.165 129 1265 all phecode
530.7 Gastroesophageal laceration-hemorrhage syndrome Digestive 0.773 0.617 – 0.969 0.0254 82 812 all phecode
530.9 Heartburn Digestive 0.977 0.927 – 1.03 0.399 1519 14928 all phecode
531 Peptic ulcer (excl. esophageal) Digestive 0.999 0.955 – 1.05 0.967 2073 20617 all phecode
531.1 Hemorrhage from gastrointestinal ulcer Digestive 0.956 0.864 – 1.06 0.385 391 3883 all phecode
531.2 Gastric ulcer Digestive 0.985 0.928 – 1.05 0.61 1201 11970 all phecode
531.3 Duodenal ulcer Digestive 0.99 0.901 – 1.09 0.842 467 4640 all phecode
531.4 Peptic ulcer, site unspecified Digestive 0.933 0.869 – 1 0.0565 804 8018 all phecode
531.5 Gastrojejunal ulcer Digestive 1.08 0.911 – 1.27 0.388 150 1500 all phecode
532 Dysphagia Digestive 0.979 0.951 – 1.01 0.162 5585 26852 all phecode
535 Gastritis and duodenitis Digestive 0.99 0.952 – 1.03 0.632 2799 27335 all phecode
535.1 Acute gastritis Digestive 0.99 0.932 – 1.05 0.737 1178 11750 all phecode
535.2 Atrophic gastritis Digestive 1.04 0.93 – 1.16 0.493 344 3413 all phecode
535.6 Duodenitis Digestive 0.973 0.87 – 1.09 0.627 334 3337 all phecode
535.8 Other specified gastritis Digestive 0.957 0.882 – 1.04 0.299 638 6354 all phecode
535.9 Gastritis and duodenitis, NOS Digestive 0.96 0.906 – 1.02 0.162 1255 12511 all phecode
536 Disorders of function of stomach Digestive 0.987 0.949 – 1.03 0.501 2911 27685 all phecode
536.3 Gastroparesis Digestive 1.07 0.987 – 1.15 0.103 706 6901 all phecode
536.7
Complications of gastrostomy, colostomy and
Complications of gastrostomy, colostomy and enterostomy
 Digestive 0.977 0.884 – 1.08 0.642 407 4059 all phecode
536.8
Dyspepsia and other specified disorders of
Dyspepsia and other specified disorders of function of stomach
 Digestive 0.966 0.924 – 1.01 0.133 2150 21094 all phecode
537 Other disorders of stomach and duodenum Digestive 1.01 0.973 – 1.05 0.604 3183 30048 all phecode
537.1 Lesions of stomach and duodenum Digestive 1.05 0.901 – 1.21 0.56 173 1725 all phecode
539 Bariatric surgery Digestive 0.926 0.878 – 0.976 0.00437 1509 15074 all phecode
540 Appendiceal conditions Digestive 1.04 0.948 – 1.14 0.399 495 4948 all phecode
540.1 Appendicitis Digestive 1.03 0.932 – 1.14 0.562 425 4239 all phecode
540.11 Acute appendicitis Digestive 1.04 0.934 – 1.16 0.464 353 3511 all phecode
550 Abdominal hernia Digestive 0.995 0.97 – 1.02 0.719 6768 37731 all phecode
550.1 Inguinal hernia Digestive 0.986 0.938 – 1.04 0.581 1744 16488 all phecode
550.2 Diaphragmatic hernia Digestive 1.01 0.968 – 1.05 0.731 2817 25849 all phecode
550.3 Femoral hernia Digestive 0.905 0.758 – 1.08 0.267 131 1291 all phecode
550.4 Umbilical hernia Digestive 0.974 0.919 – 1.03 0.36 1313 13110 all phecode
550.5 Ventral hernia Digestive 0.984 0.942 – 1.03 0.474 2241 22163 all phecode
550.6 Incisional hernia Digestive 0.995 0.94 – 1.05 0.869 1313 13111 all phecode
555
Inflammatory bowel disease and other
Inflammatory bowel disease and other gastroenteritis and colitis
 Digestive 1.01 0.96 – 1.07 0.642 1536 15153 all phecode
555.1 Regional enteritis Digestive 1.02 0.949 – 1.09 0.641 919 9095 all phecode
555.2 Ulcerative colitis Digestive 1 0.937 – 1.08 0.907 937 9315 all phecode
555.21 Ulcerative colitis (chronic) Digestive 1.03 0.945 – 1.13 0.467 537 5315 all phecode
556 Ulceration of the lower GI tract Digestive 1.01 0.928 – 1.1 0.84 632 6267 all phecode
556.1 Ulceration of intestine Digestive 1.03 0.943 – 1.13 0.505 551 5451 all phecode
556.11
Angiodysplasia of intestine (without mention of
Angiodysplasia of intestine (without mention of hemorrhage)
 Digestive 1.02 0.887 – 1.18 0.745 214 2093 all phecode
557 Intestinal malabsorption (non-celiac) Digestive 0.977 0.929 – 1.03 0.363 1716 16490 all phecode
557.1 Celiac disease Digestive 0.973 0.88 – 1.08 0.593 421 4026 all phecode
558 Noninfectious gastroenteritis Digestive 1.01 0.975 – 1.05 0.549 3458 26408 all phecode
559 Ileostomy status Digestive 1.02 0.956 – 1.09 0.519 957 9565 all phecode
560 Intestinal obstruction without mention of hernia Digestive 0.997 0.959 – 1.04 0.87 3004 24851 all phecode
560.1 Paralytic ileus Digestive 1.03 0.974 – 1.08 0.336 1627 15714 all phecode
560.2 Impaction of intestine Digestive 0.915 0.823 – 1.02 0.1 387 3779 all phecode
560.3 Peritoneal or intestinal adhesions Digestive 0.927 0.818 – 1.05 0.239 266 2647 all phecode
560.4 Other intestinal obstruction Digestive 0.982 0.933 – 1.03 0.491 1651 16170 all phecode
561 Symptoms involving digestive system Digestive 0.957 0.918 – 0.997 0.0347 2608 21766 all phecode
562 Diverticulosis and diverticulitis Digestive 0.983 0.955 – 1.01 0.236 6295 23431 all phecode
562.1 Diverticulosis Digestive 0.986 0.958 – 1.01 0.323 6246 23383 all phecode
562.2 Diverticulitis Digestive 0.959 0.911 – 1.01 0.117 1611 15162 all phecode
564 Functional digestive disorders Digestive 0.995 0.973 – 1.02 0.635 11411 28676 all phecode
564.1 Irritable Bowel Syndrome Digestive 0.993 0.958 – 1.03 0.719 3457 22266 all phecode
564.9 Personal history of diseases of digestive system Digestive 0.985 0.948 – 1.02 0.434 3074 25861 all phecode
565 Anal and rectal conditions Digestive 1.02 0.98 – 1.05 0.395 3355 30757 all phecode
565.1 Anal and rectal polyp Digestive 1 0.945 – 1.06 0.97 1305 12649 all phecode
567 Peritonitis and retroperitoneal infections Digestive 0.997 0.943 – 1.05 0.923 1364 13616 all phecode
568 Other disorders of peritoneum Digestive 0.965 0.918 – 1.01 0.156 1705 17038 all phecode
568.1
Peritoneal adhesions (postoperative)
Peritoneal adhesions (postoperative) (postinfection)
 Digestive 0.94 0.887 – 0.997 0.0395 1247 12468 all phecode
569 Other disorders of intestine Digestive 1 0.978 – 1.03 0.853 8079 35231 all phecode
569.1 Toxic gastroenteritis and colitis Digestive 1.13 1 – 1.27 0.0484 326 3260 all phecode
569.2 Gastrointestinal complications Digestive 0.966 0.914 – 1.02 0.218 1395 13933 all phecode
571 Chronic liver disease and cirrhosis Digestive 1.01 0.977 – 1.04 0.614 4610 32562 all phecode
571.5 Other chronic nonalcoholic liver disease Digestive 1.01 0.974 – 1.04 0.742 4342 32234 all phecode
571.51 Cirrhosis of liver without mention of alcohol Digestive 0.998 0.935 – 1.06 0.941 1018 10095 all phecode
571.6 Primary biliary cirrhosis Digestive 0.936 0.804 – 1.09 0.398 179 1790 all phecode
571.8
Liver abscess and sequelae of chronic liver
Liver abscess and sequelae of chronic liver disease
 Digestive 1.01 0.946 – 1.08 0.752 950 9498 all phecode
571.81 Portal hypertension Digestive 0.957 0.879 – 1.04 0.312 573 5730 all phecode
572 Ascites (non malignant) Digestive 0.98 0.938 – 1.02 0.353 2278 22675 all phecode
573 Other disorders of liver Digestive 1.01 0.979 – 1.04 0.632 5599 33620 all phecode
573.1 Chronic passive congestion of liver Digestive 0.901 0.749 – 1.08 0.266 136 1359 all phecode
573.2 Liver replaced by transplant Digestive 1.08 0.959 – 1.22 0.202 292 2920 all phecode
573.3 Hepatomegaly Digestive 0.945 0.859 – 1.04 0.242 470 4700 all phecode
573.4 Acute and subacute necrosis of liver Digestive 1.07 0.952 – 1.2 0.258 316 3149 all phecode
573.5 Jaundice (not of newborn) Digestive 0.986 0.922 – 1.05 0.67 958 9496 all phecode
573.6
Nonspecific elevation of levels of transaminase
Nonspecific elevation of levels of transaminase or lactic acid dehydrogenase [LDH]
 Digestive 1.01 0.972 – 1.05 0.59 2756 26470 all phecode
573.7 Abnormal results of function study of liver Digestive 0.997 0.96 – 1.04 0.889 3018 27774 all phecode
573.9 Abnormal serum enzyme levels Digestive 1.02 0.987 – 1.05 0.25 4679 33866 all phecode
574 Cholelithiasis and cholecystitis Digestive 0.959 0.925 – 0.995 0.0245 3177 30809 all phecode
574.1 Cholelithiasis Digestive 0.958 0.922 – 0.995 0.0256 2924 28874 all phecode
574.11 Cholelithiasis with acute cholecystitis Digestive 0.897 0.803 – 1 0.0521 342 3412 all phecode
574.12 Cholelithiasis with other cholecystitis Digestive 0.973 0.891 – 1.06 0.537 553 5501 all phecode
574.2 Calculus of bile duct Digestive 0.957 0.891 – 1.03 0.223 852 8503 all phecode
574.3 Cholecystitis without cholelithiasis Digestive 0.954 0.888 – 1.02 0.191 822 8181 all phecode
575 Other biliary tract disease Digestive 0.962 0.922 – 1.01 0.0837 2266 22555 all phecode
575.1 Cholangitis Digestive 1.04 0.934 – 1.16 0.465 354 3530 all phecode
575.2 Obstruction of bile duct Digestive 0.973 0.895 – 1.06 0.518 621 6201 all phecode
575.6 Cholesterolosis of gallbladder Digestive 1.02 0.88 – 1.17 0.821 207 2063 all phecode
575.7 Other disorders of gallbladder Digestive 0.935 0.874 – 0.999 0.0471 939 9382 all phecode
575.8 Other disorders of biliary tract Digestive 0.961 0.904 – 1.02 0.199 1154 11523 all phecode
575.9
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of biliary tract
 Digestive 0.972 0.856 – 1.1 0.665 260 2600 all phecode
577 Diseases of pancreas Digestive 0.955 0.914 – 0.997 0.037 2225 22106 all phecode
577.1 Acute pancreatitis Digestive 0.93 0.876 – 0.986 0.0152 1212 12110 all phecode
577.2 Chronic pancreatitis Digestive 0.944 0.861 – 1.03 0.219 495 4950 all phecode
577.3 Cyst and pseudocyst of pancreas Digestive 0.973 0.891 – 1.06 0.536 570 5601 all phecode
578 Gastrointestinal hemorrhage Digestive 1 0.969 – 1.03 0.997 4554 37045 all phecode
578.1 Hematemesis Digestive 1.02 0.929 – 1.12 0.662 485 4842 all phecode
578.2 Blood in stool Digestive 0.986 0.947 – 1.03 0.475 2743 26554 all phecode
578.8 Hemorrhage of rectum and anus Digestive 1.02 0.974 – 1.06 0.414 2210 21750 all phecode
578.9 Hemorrhage of gastrointestinal tract Digestive 0.997 0.945 – 1.05 0.896 1562 15345 all phecode
579 Other symptoms involving abdomen and pelvis Digestive 0.988 0.958 – 1.02 0.461 4431 34209 all phecode
579.2 Splenomegaly Digestive 1.05 0.976 – 1.14 0.18 730 7262 all phecode
579.8 Nonspecific abnormal findings in stool contents Digestive 0.986 0.933 – 1.04 0.605 1410 13877 all phecode
580 Nephritis; nephrosis; renal sclerosis Genitourinary 1.01 0.966 – 1.07 0.556 1881 15516 all phecode
580.1 Glomerulonephritis Genitourinary 1.02 0.915 – 1.13 0.774 401 3992 all phecode
580.11 Proliferative glomerulonephritis Genitourinary 1.06 0.897 – 1.26 0.473 146 1440 all phecode
580.12 Non-proliferative glomerulonephritis Genitourinary 0.979 0.804 – 1.19 0.831 114 1128 all phecode
580.13 Acute glomerulonephritis, NOS Genitourinary 0.962 0.743 – 1.24 0.766 61 600 all phecode
580.14 Chronic glomerulonephritis, NOS Genitourinary 1.04 0.92 – 1.18 0.511 277 2760 all phecode
580.2
Nephrotic syndrome without mention of
Nephrotic syndrome without mention of glomerulonephritis
 Genitourinary 0.969 0.841 – 1.12 0.664 221 2193 all phecode
580.3
Nephritis and nephropathy without mention of
Nephritis and nephropathy without mention of glomerulonephritis
 Genitourinary 1.02 0.965 – 1.08 0.494 1502 11930 all phecode
580.31
Nephritis and nephropathy in diseases
Nephritis and nephropathy in diseases classified elsewhere
 Genitourinary 0.985 0.921 – 1.05 0.668 992 7228 all phecode
580.32
Nephritis and nephropathy with pathological
Nephritis and nephropathy with pathological lesion
 Genitourinary 1.07 0.984 – 1.16 0.115 683 6612 all phecode
580.4 Renal sclerosis, NOS Genitourinary 1.02 0.917 – 1.15 0.667 340 3400 all phecode
585 Renal failure Genitourinary 0.986 0.961 – 1.01 0.305 7470 32340 all phecode
585.1 Acute renal failure Genitourinary 0.991 0.96 – 1.02 0.608 4265 27230 all phecode
585.2 Renal failure NOS Genitourinary 0.976 0.908 – 1.05 0.5 832 8162 all phecode
585.3 Chronic renal failure [CKD] Genitourinary 0.991 0.962 – 1.02 0.536 5580 29470 all phecode
585.31 Renal dialysis Genitourinary 0.948 0.879 – 1.02 0.16 747 7423 all phecode
585.32 End stage renal disease Genitourinary 0.976 0.915 – 1.04 0.462 1007 9783 all phecode
585.33 Chronic Kidney Disease, Stage III Genitourinary 0.997 0.96 – 1.04 0.861 3209 21312 all phecode
585.34 Chronic Kidney Disease, Stage IV Genitourinary 0.971 0.909 – 1.04 0.378 977 9190 all phecode
585.4 Chronic kidney disease, Stage I or II Genitourinary 0.996 0.939 – 1.06 0.891 1227 11191 all phecode
586 Other disorders of the kidney and ureters Genitourinary 1 0.976 – 1.03 0.899 7628 34189 all phecode
586.1 Anatomical abnormatilies of kidney and ureters Genitourinary 1.07 0.96 – 1.19 0.222 349 3480 all phecode
586.11 Small kidney Genitourinary 1.07 0.927 – 1.24 0.35 210 2093 all phecode
586.12 Vesicoureteral reflux Genitourinary 1.03 0.868 – 1.23 0.709 136 1360 all phecode
586.2 Cyst of kidney, acquired Genitourinary 0.996 0.942 – 1.05 0.901 1381 12912 all phecode
586.3 Vascular disorders of kidney/hypertrophy Genitourinary 1.09 0.938 – 1.26 0.262 187 1862 all phecode
586.4 Stricture/obstruction of ureter Genitourinary 0.968 0.923 – 1.02 0.191 1821 17115 all phecode
587 Kidney replaced by transpant Genitourinary 0.958 0.892 – 1.03 0.245 819 8134 all phecode
588 Disorders resulting from impaired renal function Genitourinary 0.965 0.903 – 1.03 0.294 976 9389 all phecode
588.1 Renal osteodystrophy Genitourinary 1.05 0.934 – 1.19 0.394 290 2900 all phecode
588.2 Secondary hyperparathyroidism (of renal origin) Genitourinary 0.966 0.896 – 1.04 0.364 755 7275 all phecode
589 Abnormal results of function study of kidney Genitourinary 1 0.938 – 1.07 0.984 1007 9834 all phecode
590 Pyelonephritis Genitourinary 1.02 0.968 – 1.08 0.436 1461 14350 all phecode
591 Urinary tract infection Genitourinary 1.01 0.986 – 1.03 0.466 9873 32513 all phecode
592 Cystitis and urethritis Genitourinary 1.03 0.99 – 1.07 0.148 3038 24207 all phecode
592.1 Cystitis Genitourinary 1.03 0.989 – 1.07 0.155 2880 23279 all phecode
592.11 Acute cystitis Genitourinary 1.04 0.987 – 1.09 0.152 1783 16452 all phecode
592.12 Chronic cystitis Genitourinary 0.985 0.865 – 1.12 0.824 239 2343 all phecode
592.13 Chronic interstitial cystitis Genitourinary 1.01 0.914 – 1.11 0.86 431 4310 all phecode
592.2 Urethritis and urethral syndrome Genitourinary 1.12 0.963 – 1.3 0.143 210 2093 all phecode
593 Hematuria Genitourinary 1.02 0.993 – 1.06 0.128 4859 32063 all phecode
593.1 Gross hematuria Genitourinary 0.983 0.933 – 1.03 0.507 1585 14824 all phecode
593.2 Microscopic hematuria Genitourinary 1.06 0.998 – 1.13 0.0584 1049 10301 all phecode
594 Urinary calculus Genitourinary 1.01 0.981 – 1.03 0.607 6707 38209 all phecode
594.1 Calculus of kidney Genitourinary 1.01 0.983 – 1.04 0.477 6273 38051 all phecode
594.2 Calculus of lower urinary tract Genitourinary 1.08 0.969 – 1.2 0.168 366 3638 all phecode
594.3 Calculus of ureter Genitourinary 1.01 0.953 – 1.06 0.801 1361 13561 all phecode
594.8 Renal colic Genitourinary 1.05 0.943 – 1.18 0.361 356 3560 all phecode
595 Hydronephrosis Genitourinary 0.969 0.921 – 1.02 0.22 1670 16658 all phecode
596 Other disorders of bladder Genitourinary 1.01 0.976 – 1.05 0.499 3074 28020 all phecode
596.1 Bladder neck obstruction Genitourinary 0.943 0.85 – 1.05 0.276 400 3942 all phecode
596.5 Functional disorders of bladder Genitourinary 1.01 0.965 – 1.07 0.589 1719 17049 all phecode
597 Other disorders of urethra and urinary tract Genitourinary 0.997 0.939 – 1.06 0.91 1211 11998 all phecode
597.1 Urethral stricture (not specified as infectious) Genitourinary 0.947 0.873 – 1.03 0.182 661 6537 all phecode
597.2 Urinary complications NEC Genitourinary 0.987 0.926 – 1.05 0.687 1049 10479 all phecode
597.8 Urethral hypermobility/ISD Genitourinary 0.944 0.814 – 1.09 0.441 189 1873 all phecode
598 Abnormal findings on examination of urine Genitourinary 1.04 0.872 – 1.24 0.655 138 1356 all phecode
598.4 Other cells and casts in urine Genitourinary 1.07 0.882 – 1.29 0.506 122 1192 all phecode
599 Other symptoms/disorders or the urinary system Genitourinary 1 0.982 – 1.02 0.811 14168 30681 all phecode
599.1 Urinary obstruction Genitourinary 0.899 0.834 – 0.97 0.00581 728 6861 all phecode
599.2 Retention of urine Genitourinary 1.01 0.979 – 1.04 0.561 5034 28305 all phecode
599.3 Dysuria Genitourinary 1.01 0.978 – 1.04 0.558 4397 27849 all phecode
599.4 Urinary incontinence Genitourinary 1.01 0.981 – 1.04 0.493 5599 26960 all phecode
599.5 Frequency of urination and polyuria Genitourinary 1 0.972 – 1.03 0.934 5498 28723 all phecode
599.6 Oliguria and anuria Genitourinary 0.969 0.892 – 1.05 0.457 599 5902 all phecode
599.7 Urethral discharge Genitourinary 0.999 0.829 – 1.2 0.993 118 1175 all phecode
599.8 Other symptoms involving urinary system Genitourinary 1.02 0.986 – 1.05 0.314 5446 27963 all phecode
599.9 Other abnormality of urination Genitourinary 0.989 0.952 – 1.03 0.569 3041 24877 all phecode
600 Hyperplasia of prostate Genitourinary 0.962 0.925 – 0.999 0.0443 4063 11364 all phecode
601 Inflammatory diseases of prostate Genitourinary 0.934 0.877 – 0.995 0.0357 1044 9665 all phecode
601.1 Prostatitis Genitourinary 0.966 0.878 – 1.06 0.475 477 4596 all phecode
601.11 Acute prostatitis Genitourinary 1.06 0.874 – 1.29 0.554 124 1200 all phecode
601.12 Chronic prostatitis Genitourinary 0.953 0.773 – 1.18 0.654 95 943 all phecode
601.3 Orchitis and epididymitis Genitourinary 0.918 0.827 – 1.02 0.107 389 3822 all phecode
601.4 Balanoposthitis Genitourinary 0.84 0.702 – 1 0.0562 127 1224 all phecode
601.8
Other inflammatory disorders of male genital
Other inflammatory disorders of male genital organs
 Genitourinary 0.964 0.816 – 1.14 0.669 161 1591 all phecode
602 Other disorders of prostate Genitourinary 0.975 0.875 – 1.09 0.651 361 3399 all phecode
602.3 Dysplasia of prostate Genitourinary 0.937 0.738 – 1.19 0.59 77 730 all phecode
603 Other disorders of testis Genitourinary 0.922 0.836 – 1.02 0.105 440 4354 all phecode
603.1 Hydrocele Genitourinary 0.848 0.751 – 0.957 0.00762 293 2882 all phecode
603.2 Spermatocele Genitourinary 1.01 0.858 – 1.19 0.9 156 1539 all phecode
604 Disorders of penis Genitourinary 0.96 0.888 – 1.04 0.311 685 6748 all phecode
604.1 Redundant prepuce and phimosis/BXO Genitourinary 1.05 0.89 – 1.24 0.55 155 1540 all phecode
604.3 Peyronie's disease Genitourinary 0.899 0.78 – 1.04 0.145 215 2132 all phecode
605 Erectile dysfunction [ED] Genitourinary 0.977 0.941 – 1.01 0.219 3776 12700 all phecode
608 Other disorders of male genital organs Genitourinary 0.96 0.911 – 1.01 0.115 1645 13758 all phecode
609 Male infertility and abnormal spermatozoa Genitourinary 0.906 0.819 – 1 0.0552 424 4196 all phecode
609.1 Infertility, male Genitourinary 0.905 0.803 – 1.02 0.0984 302 2992 all phecode
609.11 Azoospermia and oligospermia Genitourinary 0.817 0.663 – 1.01 0.058 95 950 all phecode
609.2 Abnormal spermatozoa Genitourinary 1 0.849 – 1.18 0.981 154 1519 all phecode
610 Benign mammary dysplasias Genitourinary 1.01 0.977 – 1.05 0.499 3683 16548 all phecode
610.1 Cystic mastopathy Genitourinary 0.98 0.931 – 1.03 0.44 1633 14191 all phecode
610.2 Fibroadenosis of breast Genitourinary 0.902 0.695 – 1.17 0.441 60 600 all phecode
610.4 Benign neoplasm of breast Genitourinary 1.03 0.989 – 1.07 0.16 2837 16430 all phecode
610.8 Other specified benign mammary dysplasias Genitourinary 0.989 0.933 – 1.05 0.708 1269 12191 all phecode
611 Abnormal findings on mammogram or breast exam Genitourinary 1.03 0.996 – 1.06 0.0839 6067 18690 all phecode
611.1 Abnormal mammogram Genitourinary 1.02 0.989 – 1.06 0.202 4980 16120 all phecode
611.11 Mammographic microcalcification Genitourinary 1.02 0.962 – 1.09 0.463 1122 10394 all phecode
611.3 Lump or mass in breast Genitourinary 1.02 0.984 – 1.06 0.263 3549 18572 all phecode
612
Breast conditions, congenital or relating to
Breast conditions, congenital or relating to hormones
 Genitourinary 0.992 0.931 – 1.06 0.804 1051 10425 all phecode
612.1 Galactorrhea Genitourinary 1.15 0.959 – 1.37 0.132 139 1390 all phecode
612.2 Hypertrophy of breast (Gynecomastia) Genitourinary 0.979 0.91 – 1.05 0.568 800 7962 all phecode
612.3 Congenital anomalies of breast Genitourinary 0.8 0.636 – 1 0.0546 83 810 all phecode
613 Other nonmalignant breast conditions Genitourinary 1.02 0.983 – 1.05 0.314 3897 22072 all phecode
613.1 Inflammatory disease of breast Genitourinary 0.965 0.886 – 1.05 0.419 593 5874 all phecode
613.5 Mastodynia Genitourinary 1 0.951 – 1.05 0.992 1675 16203 all phecode
613.7 Other signs and symptoms in breast Genitourinary 1.01 0.941 – 1.08 0.788 883 8754 all phecode
613.8 Other specified disorders of breast Genitourinary 1.04 0.967 – 1.11 0.318 932 9248 all phecode
613.9 Breast disorder NOS Genitourinary 1.01 0.957 – 1.07 0.704 1465 14174 all phecode
614 Inflammatory diseases of female pelvic organs Genitourinary 1.01 0.975 – 1.05 0.555 3715 19647 all phecode
614.1
Pelvic peritoneal adhesions, female
Pelvic peritoneal adhesions, female (postoperative) (postinfection)
 Genitourinary 1.04 0.928 – 1.17 0.502 337 3370 all phecode
614.3 Pelvic inflammatory disease (PID) Genitourinary 1.06 0.96 – 1.16 0.261 478 4773 all phecode
614.31 Acute inflammatory pelvic disease Genitourinary 1.08 0.86 – 1.34 0.525 94 933 all phecode
614.32 Chronic inflammatory pelvic disease Genitourinary 1.08 0.929 – 1.26 0.308 186 1842 all phecode
614.33 Pelvic inflammatory disease, NOS Genitourinary 1.07 0.935 – 1.23 0.319 246 2460 all phecode
614.4 Inflammatory diseases of uterus, except cervix Genitourinary 1.08 0.921 – 1.26 0.35 165 1639 all phecode
614.5
Inflammatory disease of cervix, vagina, and
Inflammatory disease of cervix, vagina, and vulva
 Genitourinary 1 0.967 – 1.04 0.804 3180 19539 all phecode
614.51 Cervicitis and endocervicitis Genitourinary 1.05 0.928 – 1.19 0.43 264 2640 all phecode
614.52 Vaginitis and vulvovaginitis Genitourinary 1.01 0.965 – 1.05 0.807 2732 18924 all phecode
614.53 Cyst or abscess of Bartholin's gland Genitourinary 0.958 0.797 – 1.15 0.651 132 1311 all phecode
614.54 Abscess or ulceration of vulva Genitourinary 0.959 0.837 – 1.1 0.547 225 2244 all phecode
615 Endometriosis Genitourinary 0.969 0.92 – 1.02 0.239 1585 14666 all phecode
618 Genital prolapse Genitourinary 1.01 0.964 – 1.06 0.691 2079 17915 all phecode
618.1 Prolapse of vaginal walls Genitourinary 1.02 0.961 – 1.07 0.586 1408 13456 all phecode
618.2 Uterine/Uterovaginal prolapse Genitourinary 1 0.919 – 1.09 0.969 542 5390 all phecode
618.5 Prolapse of vaginal vault after hysterectomy Genitourinary 1.15 1.02 – 1.29 0.0217 317 3162 all phecode
618.6 Vaginal enterocele, congenital or acquired Genitourinary 1.01 0.919 – 1.12 0.801 441 4394 all phecode
619 Noninflammatory female genital disorders Genitourinary 0.987 0.958 – 1.02 0.401 5728 18687 all phecode
619.1
Noninflammatory disorders of ovary, fallopian
Noninflammatory disorders of ovary, fallopian tube, and broad ligament
 Genitourinary 0.96 0.905 – 1.02 0.181 1233 12082 all phecode
619.2 Disorders of uterus, NEC Genitourinary 1.04 0.95 – 1.13 0.428 591 5897 all phecode
619.3 Noninflammatory disorders of cervix Genitourinary 0.948 0.863 – 1.04 0.265 483 4823 all phecode
619.4 Noninflammatory disorders of vagina Genitourinary 0.976 0.935 – 1.02 0.254 2525 18404 all phecode
619.5 Noninflammatory disorders of vulva and perineum Genitourinary 1.01 0.949 – 1.07 0.82 1189 11717 all phecode
620 Dysplasia of female genital organs Genitourinary 0.957 0.863 – 1.06 0.406 395 3950 all phecode
620.1 Dysplasia of cervix Genitourinary 0.992 0.851 – 1.16 0.923 178 1780 all phecode
621 Endometrial hyperplasia Genitourinary 0.913 0.828 – 1.01 0.0715 437 4370 all phecode
622 Polyp of female genital organs Genitourinary 0.946 0.896 – 0.999 0.0457 1449 14264 all phecode
622.1 Polyp of corpus uteri Genitourinary 0.946 0.89 – 1.01 0.0733 1132 11189 all phecode
622.2 Mucous polyp of cervix Genitourinary 0.91 0.825 – 1 0.0607 445 4444 all phecode
623 Hypertrophy of female genital organs Genitourinary 0.946 0.881 – 1.02 0.122 824 8165 all phecode
624 Symptoms involving female genital tract Genitourinary 0.951 0.898 – 1.01 0.0786 1348 12518 all phecode
624.1 Dystrophy of female genital tract Genitourinary 1.03 0.895 – 1.19 0.673 216 2155 all phecode
624.2 Atrophy of female genital tract Genitourinary 0.872 0.68 – 1.12 0.28 64 615 all phecode
624.9 stress incontinence, female Genitourinary 0.997 0.95 – 1.05 0.895 1935 15408 all phecode
625
Pain and other symptoms associated with female
Pain and other symptoms associated with female genital organs
 Genitourinary 0.992 0.962 – 1.02 0.597 5653 17303 all phecode
625.1 Dyspareunia Genitourinary 1.02 0.965 – 1.08 0.451 1267 12474 all phecode
626
Disorders of menstruation and other abnormal
Disorders of menstruation and other abnormal bleeding from female genital tract
 Genitourinary 0.979 0.949 – 1.01 0.181 5940 15585 all phecode
626.1 Irregular menstrual cycle/bleeding Genitourinary 0.972 0.939 – 1.01 0.114 4315 14604 all phecode
626.11 Absent or infrequent menstruation Genitourinary 0.974 0.914 – 1.04 0.426 1062 8531 all phecode
626.12 Excessive or frequent menstruation Genitourinary 0.966 0.922 – 1.01 0.151 2097 11991 all phecode
626.13 Irregular menstrual cycle Genitourinary 0.981 0.934 – 1.03 0.432 1957 12265 all phecode
626.14 Irregular menstrual bleeding Genitourinary 0.933 0.873 – 0.997 0.0409 970 8996 all phecode
626.15 Infertility, female, associated with anovulation Genitourinary 0.967 0.87 – 1.07 0.532 394 3789 all phecode
626.2 Dysmenorrhea Genitourinary 0.982 0.928 – 1.04 0.54 1373 9857 all phecode
626.4 Premenstrual tension syndromes Genitourinary 0.952 0.851 – 1.07 0.392 336 3308 all phecode
626.8 Infertility, female Genitourinary 1.01 0.934 – 1.08 0.877 817 6741 all phecode
627 Menopausal and postmenopausal disorders Genitourinary 0.978 0.946 – 1.01 0.199 4560 14557 all phecode
627.1 Postmenopausal bleeding Genitourinary 0.959 0.902 – 1.02 0.186 1146 10338 all phecode
627.2 Symptomatic menopause Genitourinary 0.983 0.944 – 1.02 0.403 3017 13763 all phecode
627.21 Symptomatic artificial menopause Genitourinary 1.04 0.881 – 1.22 0.653 152 1514 all phecode
627.22
Need for Hormone replacement therapy
Need for Hormone replacement therapy (postmenopausal)
 Genitourinary 1.01 0.9 – 1.12 0.925 356 3513 all phecode
627.3 Postmenopausal atrophic vaginitis Genitourinary 0.965 0.904 – 1.03 0.29 997 9484 all phecode
627.4 Premenopausal menorrhagia Genitourinary 0.948 0.852 – 1.06 0.329 361 3580 all phecode
627.5 Premature menopause and other ovarian failure Genitourinary 0.886 0.787 – 0.998 0.0461 309 3082 all phecode
628 Ovarian cyst Genitourinary 0.978 0.933 – 1.03 0.373 1945 13838 all phecode
634 Miscarriage; stillbirth Pregnancy Complications 1.02 0.946 – 1.09 0.652 826 8047 all phecode
634.1 Missed abortion/Hydatidiform mole Pregnancy Complications 1.06 0.929 – 1.2 0.402 273 2715 all phecode
634.3 Ectopic pregnancy Pregnancy Complications 0.983 0.817 – 1.18 0.857 117 1170 all phecode
635
Hemorrhage during pregnancy; childbirth and
Hemorrhage during pregnancy; childbirth and postpartum
 Pregnancy Complications 1.07 0.977 – 1.17 0.15 563 5309 all phecode
635.2
Antepartum hemorrhage, abruptio placentae, and
Antepartum hemorrhage, abruptio placentae, and placenta previa
 Pregnancy Complications 1.05 0.938 – 1.17 0.416 370 3629 all phecode
635.3 Placenta previa and abruptio placenta Pregnancy Complications 1.03 0.91 – 1.16 0.655 288 2850 all phecode
636
Early or threatened labor; hemorrhage in early
Early or threatened labor; hemorrhage in early pregnancy
 Pregnancy Complications 0.994 0.932 – 1.06 0.864 1080 7870 all phecode
636.1 Threatened premature labor Pregnancy Complications 0.905 0.815 – 1 0.0619 380 3799 all phecode
636.2 Early onset of delivery Pregnancy Complications 0.874 0.775 – 0.987 0.03 288 2868 all phecode
636.3 Hemorrhage in early pregnancy Pregnancy Complications 1.08 0.974 – 1.19 0.15 441 4365 all phecode
636.8 Cervical incompetence Pregnancy Complications 0.932 0.734 – 1.18 0.567 77 770 all phecode
637
Short gestation; low birth weight; and fetal
Short gestation; low birth weight; and fetal growth retardation
 Pregnancy Complications 1.01 0.805 – 1.27 0.933 85 850 all phecode
642
Hypertension complicating pregnancy
Hypertension complicating pregnancy, childbirth, and the puerperium
 Pregnancy Complications 1.05 0.959 – 1.14 0.312 585 5725 all phecode
642.1 Preeclampsia and eclampsia Pregnancy Complications 1.08 0.958 – 1.21 0.215 302 3013 all phecode
643 Excessive vomiting in pregnancy Pregnancy Complications 0.967 0.85 – 1.1 0.615 252 2506 all phecode
643.1 Hyperemesis gravidarum Pregnancy Complications 1.04 0.856 – 1.26 0.705 119 1190 all phecode
644 Anemia during pregnancy Pregnancy Complications 0.928 0.809 – 1.07 0.289 224 2224 all phecode
646 Other complications of pregnancy NEC Pregnancy Complications 1 0.931 – 1.08 0.973 855 6531 all phecode
647
Infectious and parasitic complications
Infectious and parasitic complications affecting pregnancy
 Pregnancy Complications 0.936 0.811 – 1.08 0.366 211 2093 all phecode
647.1
Infections of genitourinary tract during
Infections of genitourinary tract during pregnancy
 Pregnancy Complications 0.949 0.826 – 1.09 0.464 222 2213 all phecode
647.3 Major puerperal infection Pregnancy Complications 0.944 0.739 – 1.21 0.643 65 650 all phecode
649
Other conditions or status of the mother
Other conditions or status of the mother complicating pregnancy, childbirth, or the puerperium
 Pregnancy Complications 1.03 0.966 – 1.09 0.405 1275 8010 all phecode
649.1
Diabetes or abnormal glucose tolerance
Diabetes or abnormal glucose tolerance complicating pregnancy
 Pregnancy Complications 1.04 0.956 – 1.13 0.37 649 5687 all phecode
653
Problems associated with amniotic cavity and
Problems associated with amniotic cavity and membranes
 Pregnancy Complications 1.03 0.946 – 1.12 0.483 587 5463 all phecode
654.1
Abnormality of organs and soft tissues of
Abnormality of organs and soft tissues of pelvis complicating pregnancy, childbirth, or the puerperium
 Pregnancy Complications 1.14 0.985 – 1.32 0.0791 207 2055 all phecode
654.2 Rhesus isoimmunization in pregnancy Pregnancy Complications 1.1 0.95 – 1.28 0.2 204 2040 all phecode
655
Known or suspected fetal abnormality affecting
Known or suspected fetal abnormality affecting management of mother
 Pregnancy Complications 1.05 0.994 – 1.11 0.0843 1624 10064 all phecode
655.1 Abnormality in fetal heart rate or rhythm Pregnancy Complications 1.07 0.979 – 1.16 0.14 616 5533 all phecode
656 Other perinatal conditions of fetus or newborn Pregnancy Complications 0.99 0.923 – 1.06 0.779 898 7014 all phecode
656.2 Respiratory conditions of fetus and newborn Pregnancy Complications 0.841 0.657 – 1.08 0.17 66 660 all phecode
669 Complications of labor and delivery NEC Pregnancy Complications 1.02 0.948 – 1.09 0.621 887 6802 all phecode
671
Venous/cerebrovascular complications embolism
Venous/cerebrovascular complications embolism in pregnancy and the puerperium
 Pregnancy Complications 0.952 0.833 – 1.09 0.473 236 2351 all phecode
674 Other complications of the puerperium NEC Pregnancy Complications 0.884 0.748 – 1.04 0.148 158 1580 all phecode
676
Other disorders of the breast associated with
Other disorders of the breast associated with childbirth and disorders of lactation
 Pregnancy Complications 0.946 0.81 – 1.1 0.478 184 1814 all phecode
681 Superficial cellulitis and abscess Dermatologic 0.99 0.964 – 1.02 0.468 6500 38394 all phecode
681.1 Cellulitis and abscess of fingers/toes Dermatologic 0.996 0.939 – 1.06 0.895 1256 11462 all phecode
681.2 Cellulitis and abscess of face/neck Dermatologic 0.99 0.928 – 1.06 0.773 1007 9981 all phecode
681.3 Cellulitis and abscess of arm/hand Dermatologic 0.976 0.933 – 1.02 0.286 2123 19952 all phecode
681.5 Cellulitis and abscess of leg, except foot Dermatologic 0.977 0.935 – 1.02 0.292 2252 20944 all phecode
681.6 Cellulitis and abscess of foot, toe Dermatologic 0.997 0.95 – 1.05 0.904 1820 16893 all phecode
681.7 Cellulitis and abscess of trunk Dermatologic 0.972 0.923 – 1.02 0.287 1572 15588 all phecode
686
Other local infections of skin and subcutaneous
Other local infections of skin and subcutaneous tissue
 Dermatologic 0.983 0.941 – 1.03 0.451 2257 21750 all phecode
686.1 Carbuncle and furuncle Dermatologic 1 0.916 – 1.09 0.996 558 5504 all phecode
686.2 Impetigo Dermatologic 0.993 0.897 – 1.1 0.893 414 4117 all phecode
686.3 Pilonidal cyst Dermatologic 0.929 0.79 – 1.09 0.375 160 1594 all phecode
686.4 Pyogenic granuloma Dermatologic 0.86 0.731 – 1.01 0.0692 158 1570 all phecode
686.5 Pyoderma Dermatologic 0.983 0.764 – 1.27 0.896 63 630 all phecode
687 Symptoms affecting skin Dermatologic 1.01 0.964 – 1.07 0.593 1690 16343 all phecode
687.1 Rash and other nonspecific skin eruption Dermatologic 1 0.974 – 1.03 0.977 7007 34623 all phecode
687.3 Changes in skin texture Dermatologic 0.948 0.858 – 1.05 0.296 415 4121 all phecode
687.4 Disturbance of skin sensation Dermatologic 1.01 0.978 – 1.03 0.712 6375 34216 all phecode
689 Disorder of skin and subcutaneous tissue NOS Dermatologic 1.01 0.985 – 1.03 0.482 9311 37335 all phecode
690 Erythematosquamous dermatosis Dermatologic 1 0.972 – 1.03 0.914 5184 31581 all phecode
690.1 Seborrheic dermatitis Dermatologic 1 0.972 – 1.03 0.912 5174 31553 all phecode
691 Congenital anomalies of skin Dermatologic 0.915 0.838 – 0.999 0.047 541 5337 all phecode
691.3 Congenital pigmentary anomalies of skin Dermatologic 0.987 0.762 – 1.28 0.922 62 613 all phecode
694 Dyschromia and Vitiligo Dermatologic 0.986 0.94 – 1.03 0.556 1861 17936 all phecode
694.1 Vitiligo Dermatologic 0.936 0.791 – 1.11 0.439 137 1347 all phecode
694.2 Other dyschromia Dermatologic 0.98 0.932 – 1.03 0.433 1674 16183 all phecode
694.3 Vascular disorders of skin Dermatologic 1.18 0.931 – 1.5 0.172 82 819 all phecode
695 Erythematous conditions Dermatologic 0.946 0.916 – 0.978 0.000967 4120 30247 all phecode
695.1 Toxic erythema Dermatologic 0.862 0.685 – 1.08 0.204 70 688 all phecode
695.2 Bullous dermatoses Dermatologic 0.974 0.777 – 1.22 0.823 85 805 all phecode
695.3 Rosacea Dermatologic 0.937 0.892 – 0.983 0.00832 1816 17663 all phecode
695.4 Lupus (localized and systemic) Dermatologic 0.959 0.885 – 1.04 0.301 672 6686 all phecode
695.41 Cutaneous lupus erythematosus Dermatologic 1.02 0.89 – 1.16 0.806 247 2437 all phecode
695.42 Systemic lupus erythematosus Dermatologic 0.95 0.875 – 1.03 0.229 637 6337 all phecode
695.7 Prurigo and Lichen Dermatologic 0.918 0.845 – 0.998 0.0436 605 5986 all phecode
695.8 Other specified erythematous conditions Dermatologic 0.909 0.846 – 0.976 0.00877 812 7980 all phecode
695.81 Erythema nodosum Dermatologic 0.904 0.691 – 1.18 0.458 55 550 all phecode
695.9 Unspecified erythematous condition Dermatologic 0.994 0.919 – 1.08 0.885 679 6756 all phecode
696 Psoriasis and related disorders Dermatologic 0.971 0.919 – 1.03 0.293 1401 13832 all phecode
696.3 Pityriasis Dermatologic 0.994 0.807 – 1.22 0.953 92 904 all phecode
696.4 Psoriasis Dermatologic 0.97 0.917 – 1.03 0.303 1311 12976 all phecode
696.41 Psoriasis vulgaris Dermatologic 0.965 0.91 – 1.02 0.245 1200 11867 all phecode
696.42 Psoriatic arthropathy Dermatologic 1.02 0.906 – 1.16 0.704 282 2810 all phecode
697 Sarcoidosis Dermatologic 0.962 0.861 – 1.08 0.5 333 3330 all phecode
698 Pruritus and related conditions Dermatologic 1.01 0.971 – 1.06 0.524 2254 21889 all phecode
700 Corns and callosities Dermatologic 0.967 0.913 – 1.02 0.249 1373 10894 all phecode
701
Other hypertrophic and atrophic conditions of
Other hypertrophic and atrophic conditions of skin
 Dermatologic 1 0.979 – 1.03 0.777 7651 38050 all phecode
701.1 Keratoderma, acquired Dermatologic 1.01 0.927 – 1.11 0.792 567 5524 all phecode
701.2 Scar conditions and fibrosis of skin Dermatologic 0.966 0.925 – 1.01 0.127 2184 21550 all phecode
701.3 Circumscribed scleroderma Dermatologic 1.01 0.93 – 1.1 0.76 571 5660 all phecode
701.4 Keloid scar Dermatologic 0.959 0.88 – 1.05 0.347 578 5716 all phecode
701.5 Abnormal granulation tissue Dermatologic 0.988 0.892 – 1.09 0.818 400 3982 all phecode
702
Degenerative skin conditions and other
Degenerative skin conditions and other dermatoses
 Dermatologic 1.01 0.987 – 1.04 0.304 6956 29525 all phecode
702.1 Actinic keratosis Dermatologic 0.997 0.964 – 1.03 0.848 4171 26529 all phecode
702.2 Seborrheic keratosis Dermatologic 1.03 0.996 – 1.06 0.0956 5480 31552 all phecode
702.4 Degenerative skin disorders Dermatologic 1.21 0.971 – 1.5 0.0893 86 832 all phecode
703 Diseases of nail, NOS Dermatologic 0.979 0.93 – 1.03 0.407 1650 14562 all phecode
703.1 Ingrowing nail Dermatologic 0.96 0.896 – 1.03 0.244 920 8597 all phecode
704 Diseases of hair and hair follicles Dermatologic 0.977 0.942 – 1.01 0.224 3118 29542 all phecode
704.1 Alopecia Dermatologic 0.989 0.936 – 1.04 0.692 1408 13871 all phecode
704.11 Alopecia Areata Dermatologic 1.09 0.87 – 1.37 0.445 82 811 all phecode
704.12 Telogen effluvium Dermatologic 0.906 0.7 – 1.17 0.453 63 615 all phecode
704.2 Hirsutism Dermatologic 0.994 0.883 – 1.12 0.918 299 2946 all phecode
704.8
Other specified diseases of hair and hair
Other specified diseases of hair and hair follicles
 Dermatologic 0.99 0.942 – 1.04 0.681 1752 17189 all phecode
705 Disorders of sweat glands Dermatologic 0.927 0.851 – 1.01 0.0821 603 6012 all phecode
705.1 Dyshidrosis Dermatologic 0.914 0.775 – 1.08 0.288 154 1540 all phecode
705.3 Hidradenitis Dermatologic 0.948 0.829 – 1.09 0.44 245 2440 all phecode
705.8 Hyperhidrosis Dermatologic 1 0.943 – 1.07 0.901 1112 10986 all phecode
706 Diseases of sebaceous glands Dermatologic 0.984 0.958 – 1.01 0.263 5995 39748 all phecode
706.1 Acne Dermatologic 0.996 0.955 – 1.04 0.832 2594 22570 all phecode
706.2 Sebaceous cyst Dermatologic 0.988 0.95 – 1.03 0.551 2814 26819 all phecode
706.3 Seborrhea Dermatologic 1.2 0.909 – 1.57 0.202 59 582 all phecode
706.8 Other specified diseases of sebaceous glands Dermatologic 0.98 0.932 – 1.03 0.435 1684 15289 all phecode
707 Chronic ulcer of skin Dermatologic 0.981 0.944 – 1.02 0.329 2871 26816 all phecode
707.1 Decubitus ulcer Dermatologic 1.05 0.975 – 1.13 0.206 825 8119 all phecode
707.2 Chronic ulcer of leg or foot Dermatologic 0.998 0.938 – 1.06 0.952 1108 9992 all phecode
707.3 Chronic ulcer of unspecified site Dermatologic 0.97 0.922 – 1.02 0.231 1641 16172 all phecode
709 Diffuse diseases of connective tissue Dermatologic 1 0.948 – 1.06 0.985 1477 14427 all phecode
709.2 Sicca syndrome Dermatologic 1.04 0.952 – 1.14 0.364 505 4986 all phecode
709.3 Systemic sclerosis Dermatologic 0.854 0.745 – 0.979 0.0231 224 2209 all phecode
709.5 Dermatomyositis Dermatologic 0.993 0.801 – 1.23 0.949 92 892 all phecode
709.6
Other specified diffuse diseases of connective
Other specified diffuse diseases of connective tissue
 Dermatologic 0.878 0.712 – 1.08 0.221 90 892 all phecode
709.7 Unspecified diffuse connective tissue disease Dermatologic 0.976 0.912 – 1.04 0.482 917 9089 all phecode
710
Osteomyelitis, periostitis, and other
Osteomyelitis, periostitis, and other infections involving bone
 Musculoskeletal 0.986 0.931 – 1.05 0.642 1254 12103 all phecode
710.1 Osteomyelitis Musculoskeletal 0.991 0.934 – 1.05 0.775 1203 11636 all phecode
710.11 Acute osteomyelitis Musculoskeletal 1.03 0.945 – 1.12 0.518 590 5708 all phecode
710.12 Chronic osteomyelitis Musculoskeletal 0.961 0.881 – 1.05 0.368 531 5163 all phecode
710.19 Unspecified osteomyelitis Musculoskeletal 0.982 0.925 – 1.04 0.56 1153 11149 all phecode
711 Arthropathy associated with infections Musculoskeletal 0.932 0.843 – 1.03 0.165 410 4099 all phecode
711.1 Pyogenic arthritis Musculoskeletal 0.972 0.863 – 1.09 0.634 290 2900 all phecode
712 Infective connective tissue disorders Musculoskeletal 0.956 0.823 – 1.11 0.558 178 1776 all phecode
713
Arthropathy associated with other disorders
Arthropathy associated with other disorders classified elsewhere
 Musculoskeletal 0.966 0.861 – 1.08 0.549 314 3028 all phecode
713.5
Arthropathy associated with neurological
Arthropathy associated with neurological disorders
 Musculoskeletal 1.01 0.872 – 1.16 0.92 194 1824 all phecode
714
Rheumatoid arthritis and other inflammatory
Rheumatoid arthritis and other inflammatory polyarthropathies
 Musculoskeletal 0.978 0.935 – 1.02 0.339 2086 18159 all phecode
714.1 Rheumatoid arthritis Musculoskeletal 0.97 0.922 – 1.02 0.24 1670 15087 all phecode
714.2 Juvenile rheumatoid arthritis Musculoskeletal 1.03 0.812 – 1.31 0.806 77 767 all phecode
715 Other inflammatory spondylopathies Musculoskeletal 0.966 0.91 – 1.03 0.256 1209 11967 all phecode
715.1 Sacroiliitis NEC Musculoskeletal 0.99 0.874 – 1.12 0.875 262 2611 all phecode
715.2 Ankylosing spondylitis Musculoskeletal 0.907 0.79 – 1.04 0.166 219 2182 all phecode
716 Other arthropathies Musculoskeletal 0.98 0.96 – 1 0.062 13482 31305 all phecode
716.1 Unspecified polyarthropathy or polyarthritis Musculoskeletal 0.992 0.858 – 1.15 0.913 192 1920 all phecode
716.2 Unspecified monoarthritis Musculoskeletal 0.93 0.783 – 1.1 0.409 131 1293 all phecode
716.9 Arthropathy NOS Musculoskeletal 0.981 0.96 – 1 0.069 13410 31294 all phecode
717 Polymyalgia Rheumatica Musculoskeletal 1.1 0.961 – 1.25 0.17 261 2565 all phecode
720 Spinal stenosis Musculoskeletal 0.993 0.96 – 1.03 0.664 3958 28539 all phecode
720.1 Spinal stenosis of lumbar region Musculoskeletal 0.991 0.953 – 1.03 0.663 2872 23656 all phecode
721 Spondylosis and allied disorders Musculoskeletal 0.99 0.962 – 1.02 0.498 5509 32391 all phecode
721.1 Spondylosis without myelopathy Musculoskeletal 0.989 0.96 – 1.02 0.449 5153 31896 all phecode
721.2 Spondylosis with myelopathy Musculoskeletal 0.995 0.928 – 1.07 0.899 867 8629 all phecode
721.8 Other allied disorders of spine Musculoskeletal 0.882 0.777 – 1 0.0532 262 2600 all phecode
722 Intervertebral disc disorders Musculoskeletal 0.991 0.965 – 1.02 0.519 6284 34317 all phecode
722.1 Displacement of intervertebral disc Musculoskeletal 1.01 0.974 – 1.04 0.641 3591 31411 all phecode
722.3 Schmorl's nodes Musculoskeletal 0.964 0.806 – 1.15 0.685 126 1248 all phecode
722.6 Degeneration of intervertebral disc Musculoskeletal 0.986 0.954 – 1.02 0.424 3957 30744 all phecode
722.7 Intervertebral disc disorder with myelopathy Musculoskeletal 0.986 0.9 – 1.08 0.762 515 5140 all phecode
722.8 Postlaminectomy syndrome Musculoskeletal 1.1 0.993 – 1.23 0.0669 397 3968 all phecode
722.9 Other and unspecified disc disorder Musculoskeletal 0.994 0.948 – 1.04 0.789 1932 19288 all phecode
723 Other disorders of cervical region Musculoskeletal 1.01 0.946 – 1.08 0.731 952 9495 all phecode
723.1 Torticollis Musculoskeletal 1.12 0.985 – 1.28 0.0825 254 2522 all phecode
724 Other and unspecified disorders of back Musculoskeletal 0.999 0.967 – 1.03 0.961 4130 31954 all phecode
724.1 Disorders of sacrum Musculoskeletal 1.02 0.981 – 1.07 0.276 2307 21902 all phecode
724.2 Disorders of coccyx Musculoskeletal 1.02 0.927 – 1.13 0.638 426 4215 all phecode
724.8 Other symptoms referable to back Musculoskeletal 0.954 0.892 – 1.02 0.174 931 9295 all phecode
724.9 Other unspecified back disorders Musculoskeletal 0.998 0.945 – 1.05 0.934 1412 14087 all phecode
726 Peripheral enthesopathies and allied syndromes Musculoskeletal 0.999 0.977 – 1.02 0.966 9917 30176 all phecode
726.1 Enthesopathy Musculoskeletal 1.01 0.98 – 1.03 0.67 7507 30106 all phecode
726.2 Synoviopathy Musculoskeletal 0.946 0.887 – 1.01 0.0925 1015 9987 all phecode
726.3 Bursitis Musculoskeletal 0.974 0.928 – 1.02 0.289 1829 16722 all phecode
726.4 Calcaneal spur; Exostosis NOS Musculoskeletal 0.969 0.913 – 1.03 0.299 1193 11485 all phecode
727 Other disorders of synovium, tendon, and bursa Musculoskeletal 0.988 0.963 – 1.01 0.366 7425 30105 all phecode
727.1 Synovitis and tenosynovitis Musculoskeletal 0.999 0.962 – 1.04 0.976 3092 24998 all phecode
727.2 Bursitis disorders Musculoskeletal 0.946 0.855 – 1.05 0.278 419 4112 all phecode
727.4 Ganglion and cyst of synovium, tendon, and bursa Musculoskeletal 0.983 0.93 – 1.04 0.54 1400 13621 all phecode
727.5 Rupture of synovium Musculoskeletal 0.963 0.875 – 1.06 0.434 480 4672 all phecode
727.6 Rupture of tendon, nontraumatic Musculoskeletal 0.993 0.952 – 1.04 0.737 2461 21948 all phecode
727.7 Contracture of tendon (sheath) Musculoskeletal 1.01 0.929 – 1.1 0.809 591 5893 all phecode
727.8 Plica syndrome Musculoskeletal 1.03 0.859 – 1.24 0.739 130 1264 all phecode
728 Disorders of muscle, ligament, and fascia Musculoskeletal 0.987 0.956 – 1.02 0.411 4546 29473 all phecode
728.1 Muscular calcification and ossification Musculoskeletal 1.04 0.838 – 1.3 0.697 85 843 all phecode
728.2 Laxity of ligament or hypermobility syndrome Musculoskeletal 1.05 0.926 – 1.18 0.471 297 2949 all phecode
728.7 Fasciitis Musculoskeletal 0.983 0.945 – 1.02 0.388 2814 23463 all phecode
728.71
Contracture of palmar fascia [Dupuytren's
Contracture of palmar fascia [Dupuytren's disease]
 Musculoskeletal 0.968 0.877 – 1.07 0.52 419 4138 all phecode
729 Other disorders of soft tissues Musculoskeletal 0.993 0.959 – 1.03 0.694 3642 27471 all phecode
729.1 Rheumatism, unspecified and fibrositis Musculoskeletal 0.938 0.742 – 1.19 0.592 74 726 all phecode
729.3 Panniculitis Musculoskeletal 1.04 0.85 – 1.26 0.725 119 1174 all phecode
729.7 Nontraumatic compartment syndrome Musculoskeletal 0.906 0.712 – 1.15 0.418 67 664 all phecode
731
Osteitis deformans and osteopathies associated
Osteitis deformans and osteopathies associated with other disorders classified elsewhere
 Musculoskeletal 0.907 0.787 – 1.05 0.18 210 2091 all phecode
732 Osteochondropathies Musculoskeletal 1.03 0.928 – 1.15 0.543 361 3604 all phecode
732.1 Juvenile osteochondrosis Musculoskeletal 0.962 0.831 – 1.11 0.603 198 1969 all phecode
732.7 Osteochondritis dissecans Musculoskeletal 1.11 0.89 – 1.37 0.363 90 882 all phecode
733 Other disorders of bone and cartilage Musculoskeletal 1 0.971 – 1.04 0.886 4543 26941 all phecode
733.2 Cyst of bone Musculoskeletal 1.06 0.911 – 1.24 0.438 190 1900 all phecode
733.4 Aseptic necrosis of bone Musculoskeletal 0.98 0.896 – 1.07 0.664 518 5160 all phecode
733.6 Costochondritis Musculoskeletal 1.02 0.912 – 1.14 0.756 357 3562 all phecode
733.8 Malunion and nonunion of fracture Musculoskeletal 0.938 0.874 – 1.01 0.0789 822 8205 all phecode
733.9 Chondromalacia Musculoskeletal 1.12 0.911 – 1.38 0.278 96 960 all phecode
735 Acquired foot deformities Musculoskeletal 0.98 0.945 – 1.02 0.26 3417 29622 all phecode
735.1 Flat foot Musculoskeletal 1.03 0.943 – 1.12 0.552 620 6092 all phecode
735.2 Acquired toe deformities Musculoskeletal 1.03 0.972 – 1.09 0.327 1323 11983 all phecode
735.21 Hammer toe (acquired) Musculoskeletal 0.973 0.906 – 1.05 0.457 825 7494 all phecode
735.23 Hallux rigidus Musculoskeletal 1.12 1.01 – 1.24 0.0368 405 4005 all phecode
735.3 Hallux valgus (Bunion) Musculoskeletal 0.949 0.899 – 1 0.0555 1470 14295 all phecode
736 Other acquired deformities of limbs Musculoskeletal 0.971 0.934 – 1.01 0.149 2763 26555 all phecode
736.1 Acquired deformities of forearm Musculoskeletal 0.898 0.736 – 1.1 0.292 104 1033 all phecode
736.2 Acquired deformities of finger Musculoskeletal 1.1 0.951 – 1.26 0.206 215 2142 all phecode
736.3 Acquired deformities of hip Musculoskeletal 1.03 0.789 – 1.35 0.825 60 590 all phecode
736.4 Genu valgum or varum (acquired) Musculoskeletal 0.95 0.849 – 1.06 0.371 325 3247 all phecode
736.5 Acquired deformities of knee Musculoskeletal 0.963 0.845 – 1.1 0.573 246 2460 all phecode
736.6 Unequal leg length (acquired) Musculoskeletal 0.951 0.852 – 1.06 0.366 339 3365 all phecode
737 Curvature of spine Musculoskeletal 0.954 0.905 – 1 0.0754 1566 15543 all phecode
737.1 Kyphosis (acquired) Musculoskeletal 0.985 0.898 – 1.08 0.755 479 4748 all phecode
737.2 Lordosis (acquired) Musculoskeletal 1.02 0.809 – 1.3 0.841 70 700 all phecode
737.3 Kyphoscoliosis and scoliosis Musculoskeletal 0.95 0.895 – 1.01 0.0875 1203 11982 all phecode
738 Other acquired musculoskeletal deformity Musculoskeletal 0.979 0.939 – 1.02 0.327 2443 24187 all phecode
738.4 Acquired spondylolisthesis Musculoskeletal 0.991 0.93 – 1.06 0.783 1057 10542 all phecode
739 Contracture of joint Musculoskeletal 0.918 0.845 – 0.998 0.0447 621 6207 all phecode
740 Osteoarthrosis Musculoskeletal 0.992 0.972 – 1.01 0.446 16169 30268 all phecode
740.1 Osteoarthritis; localized Musculoskeletal 0.996 0.969 – 1.02 0.772 7005 27422 all phecode
740.11 Osteoarthrosis, localized, primary Musculoskeletal 0.995 0.967 – 1.02 0.742 6176 26155 all phecode
740.12 Osteoarthrosis, localized, secondary Musculoskeletal 0.951 0.88 – 1.03 0.202 713 7116 all phecode
740.2 Osteoarthrosis, generalized Musculoskeletal 1.02 0.966 – 1.07 0.5 1609 12092 all phecode
740.3
Osteoarthrosis involving more than one site
Osteoarthrosis involving more than one site, but not specified as generalized
 Musculoskeletal 0.98 0.881 – 1.09 0.707 373 3586 all phecode
740.9 Osteoarthrosis NOS Musculoskeletal 0.99 0.97 – 1.01 0.344 15497 30141 all phecode
741 Symptoms and disorders of the joints Musculoskeletal 1 0.978 – 1.03 0.888 8555 35884 all phecode
741.1 Ankylosis of joint Musculoskeletal 1.06 0.925 – 1.21 0.411 245 2445 all phecode
741.2 Stiffness of joint Musculoskeletal 1.03 0.969 – 1.09 0.366 1268 12594 all phecode
741.3 Difficulty in walking Musculoskeletal 0.994 0.954 – 1.04 0.783 2558 23116 all phecode
741.4 Joint effusions Musculoskeletal 1.03 0.991 – 1.08 0.124 2493 24199 all phecode
741.5 Hemarthrosis Musculoskeletal 1.16 0.936 – 1.43 0.178 94 937 all phecode
741.6 Villonodular synovitis Musculoskeletal 1.05 0.818 – 1.34 0.722 68 666 all phecode
742 Derangement of joint, non-traumatic Musculoskeletal 1.01 0.976 – 1.04 0.658 4404 33771 all phecode
742.1 Loose body in joint Musculoskeletal 1.2 1.01 – 1.42 0.0407 156 1554 all phecode
742.2
Pathological, developmental or recurrent
Pathological, developmental or recurrent dislocation
 Musculoskeletal 0.957 0.849 – 1.08 0.465 280 2792 all phecode
742.8 Articular cartilage disorder Musculoskeletal 1.06 0.931 – 1.21 0.374 245 2450 all phecode
742.9 Other derangement of joint Musculoskeletal 1 0.972 – 1.04 0.805 4107 32972 all phecode
743
Osteoporosis, osteopenia and pathological
Osteoporosis, osteopenia and pathological fracture
 Musculoskeletal 1 0.977 – 1.03 0.947 9223 36921 all phecode
743.1 Osteoporosis Musculoskeletal 0.987 0.951 – 1.02 0.474 3712 19477 all phecode
743.11 Osteoporosis NOS Musculoskeletal 0.987 0.951 – 1.02 0.485 3657 19276 all phecode
743.12 Senile osteoporosis Musculoskeletal 1.05 0.969 – 1.14 0.232 703 5804 all phecode
743.13 Other specified osteoporosis Musculoskeletal 1.05 0.938 – 1.18 0.377 321 3141 all phecode
743.2 Pathologic fracture Musculoskeletal 1.05 0.983 – 1.11 0.157 1112 10563 all phecode
743.21 Pathologic fracture of vertebrae Musculoskeletal 1.08 0.981 – 1.18 0.118 475 4629 all phecode
743.22 Pathologic fracture of femur Musculoskeletal 1.04 0.877 – 1.24 0.625 143 1391 all phecode
743.4 Stress fracture Musculoskeletal 1.08 0.972 – 1.2 0.156 407 4046 all phecode
743.9
Osteopenia or other disorder of bone and
Osteopenia or other disorder of bone and cartilage
 Musculoskeletal 1 0.979 – 1.03 0.714 6970 35237 all phecode
745 Pain in joint Musculoskeletal 0.997 0.979 – 1.02 0.781 19848 26918 all phecode
747 Cardiac and circulatory congenital anomalies Congenital Anomalies 1 0.959 – 1.05 0.935 2236 22256 all phecode
747.1 Cardiac congenital anomalies Congenital Anomalies 1 0.955 – 1.05 0.884 1767 17598 all phecode
747.11 Cardiac shunt/ heart septal defect Congenital Anomalies 0.964 0.889 – 1.05 0.378 650 6497 all phecode
747.12 Valvular heart disease/ heart chambers Congenital Anomalies 1.02 0.943 – 1.1 0.663 751 7480 all phecode
747.13 Congenital anomalies of great vessels Congenital Anomalies 1.04 0.943 – 1.16 0.405 410 4090 all phecode
747.2
Congenital anomalies of peripheral vascular
Congenital anomalies of peripheral vascular system
 Congenital Anomalies 0.987 0.901 – 1.08 0.782 501 5010 all phecode
748 Anomalies of respiratory system, congenital Congenital Anomalies 0.902 0.741 – 1.1 0.307 111 1110 all phecode
749 Congenital anomalies of face and neck Congenital Anomalies 0.943 0.864 – 1.03 0.189 555 5549 all phecode
749.1 Cleft palate Congenital Anomalies 1.09 0.878 – 1.36 0.427 97 970 all phecode
749.2 Congenital anomalies of skull and face bones Congenital Anomalies 1.05 0.857 – 1.28 0.659 105 1041 all phecode
750 Digestive congenital anomalies Congenital Anomalies 0.975 0.911 – 1.04 0.47 893 8919 all phecode
750.1 Upper gastrointestinal congenital anomalies Congenital Anomalies 1.03 0.924 – 1.14 0.613 366 3655 all phecode
750.11 Esophageal atresia/tracheoesophageal fistula Congenital Anomalies 1.1 0.911 – 1.33 0.32 119 1185 all phecode
750.13 Congenital anomalies of mouth/tongue Congenital Anomalies 0.889 0.729 – 1.08 0.245 99 982 all phecode
750.14 Congenital anomalies of esophagus Congenital Anomalies 1.17 0.975 – 1.4 0.0912 134 1332 all phecode
750.15 Congenital anomalies of stomach Congenital Anomalies 0.992 0.759 – 1.3 0.951 60 593 all phecode
750.2 Lower gastrointestinal congenital anomalies Congenital Anomalies 0.938 0.858 – 1.02 0.154 531 5300 all phecode
750.21 Congenital anomalies of intestine Congenital Anomalies 1 0.894 – 1.13 0.957 313 3129 all phecode
750.22
Congenital anomaly of gallbladder, bile ducts
Congenital anomaly of gallbladder, bile ducts, liver, pancreas
 Congenital Anomalies 0.843 0.735 – 0.966 0.0141 222 2214 all phecode
751 Genitourinary congenital anomalies Congenital Anomalies 0.987 0.942 – 1.03 0.577 2008 19975 all phecode
751.1 Congenital anomalies of genital organs Congenital Anomalies 1.07 0.981 – 1.17 0.125 574 5740 all phecode
751.11 Congenital anomalies of female genital organs Congenital Anomalies 1.08 0.974 – 1.2 0.141 384 3840 all phecode
751.12 Congenital anomalies of male genital organs Congenital Anomalies 1.06 0.893 – 1.25 0.52 153 1527 all phecode
751.2 Congenital anomalies of urinary system Congenital Anomalies 0.96 0.908 – 1.01 0.15 1379 13704 all phecode
751.21 Cystic kidney disease Congenital Anomalies 0.95 0.89 – 1.02 0.132 976 9685 all phecode
751.22 Other specified congenital anomalies of kidney Congenital Anomalies 1.01 0.898 – 1.14 0.848 294 2927 all phecode
751.3 Obstructive genitourinary defect Congenital Anomalies 1.05 0.903 – 1.23 0.515 182 1809 all phecode
752 Nervous system congenital anomalies Congenital Anomalies 0.985 0.926 – 1.05 0.63 1133 11313 all phecode
752.1 Neural tube defects Congenital Anomalies 0.976 0.911 – 1.05 0.487 923 9209 all phecode
752.11 Spina bifida Congenital Anomalies 1.05 0.899 – 1.22 0.551 176 1760 all phecode
752.2
Other specified congenital anomalies of nervous
Other specified congenital anomalies of nervous system
 Congenital Anomalies 1.03 0.9 – 1.17 0.684 232 2320 all phecode
753 Congenital anomalies of the eye Congenital Anomalies 1.07 0.931 – 1.24 0.333 207 2051 all phecode
753.1 Congenital cataract and lens anomalies Congenital Anomalies 1.22 0.933 – 1.59 0.148 58 580 all phecode
753.2 Congenital anomalies of posterior segment of eye Congenital Anomalies 1.1 0.831 – 1.46 0.508 56 546 all phecode
754 Congenital musculoskeletal deformities of spine Congenital Anomalies 0.955 0.9 – 1.01 0.134 1216 12116 all phecode
754.1 Lumbosacral spondylolysis, congenital Congenital Anomalies 0.959 0.799 – 1.15 0.648 135 1333 all phecode
754.2 Spondylolisthesis, congenital Congenital Anomalies 0.949 0.869 – 1.04 0.248 558 5570 all phecode
755 Congenital anomalies of limbs Congenital Anomalies 0.969 0.898 – 1.05 0.412 747 7458 all phecode
755.1 Congenital deformities of feet Congenital Anomalies 0.976 0.876 – 1.09 0.654 368 3663 all phecode
755.4
Congenital anomalies of upper limb, including
Congenital anomalies of upper limb, including shoulder girdle
 Congenital Anomalies 0.901 0.704 – 1.15 0.41 74 740 all phecode
755.6
Other congenital anomalies of lower limb
Other congenital anomalies of lower limb, including pelvic girdle
 Congenital Anomalies 0.967 0.861 – 1.09 0.568 321 3205 all phecode
755.61 Congenital hip dysplasia and deformity Congenital Anomalies 1.04 0.892 – 1.21 0.623 185 1847 all phecode
756 Other congenital musculoskeletal anomalies Congenital Anomalies 0.993 0.938 – 1.05 0.799 1358 13579 all phecode
756.1 Congenital anomalies of abdominal wall; diaphram Congenital Anomalies 0.936 0.725 – 1.21 0.613 68 680 all phecode
756.2
Pectus and other congenital anomalies of
Pectus and other congenital anomalies of ribs/sternum
 Congenital Anomalies 1.06 0.834 – 1.36 0.614 71 694 all phecode
756.3
Congenital anomalies of muscle, tendon, fascia
Congenital anomalies of muscle, tendon, fascia, and connective tissue
 Congenital Anomalies 1.02 0.91 – 1.13 0.773 335 3346 all phecode
756.5 Congenital osteodystrophies Congenital Anomalies 1.01 0.948 – 1.08 0.703 1003 10014 all phecode
757 Congenital anomalies of the integument Congenital Anomalies 1.03 0.931 – 1.14 0.548 401 4001 all phecode
758 Chromosomal anomalies and genetic disorders Congenital Anomalies 0.945 0.814 – 1.1 0.464 185 1845 all phecode
758.1 Chromosomal anomalies Congenital Anomalies 0.965 0.811 – 1.15 0.685 135 1349 all phecode
759 Other and unspecified congenital anomalies Congenital Anomalies 0.969 0.888 – 1.06 0.482 557 5566 all phecode
759.1 Anomalies of endocrine glands, congenital Congenital Anomalies 0.904 0.711 – 1.15 0.414 71 710 all phecode
760 Back pain Symptoms 1 0.984 – 1.02 0.722 16037 30719 all phecode
761 Cervicalgia Symptoms 0.997 0.971 – 1.02 0.823 6528 39755 all phecode
763
Thoracic or lumbosacral neuritis or
Thoracic or lumbosacral neuritis or radiculitis, unspecified
 Symptoms 0.987 0.953 – 1.02 0.45 3657 32599 all phecode
764 Sciatica Symptoms 0.999 0.964 – 1.03 0.941 3542 32015 all phecode
765 Cervical radiculitis Symptoms 0.991 0.944 – 1.04 0.708 1799 17851 all phecode
766 Neuralgia, neuritis, and radiculitis NOS Symptoms 0.975 0.947 – 1 0.0897 5124 37132 all phecode
767 Cervicocranial/Cervicobrachial syndrome Symptoms 1.04 0.858 – 1.25 0.719 117 1168 all phecode
769 Nonallopathic lesions NEC Symptoms 1.02 0.956 – 1.08 0.593 1131 11220 all phecode
770 Myalgia and myositis unspecified Symptoms 1.01 0.979 – 1.04 0.591 5533 34303 all phecode
771 Musculoskeletal symptoms referable to limbs Symptoms 0.971 0.942 – 1 0.0535 4799 35575 all phecode
771.1 Swelling of limb Symptoms 0.961 0.934 – 0.988 0.00535 5743 35539 all phecode
771.2 Cramp of limb Symptoms 1.02 0.957 – 1.09 0.555 1079 10568 all phecode
772 Symptoms of the muscles Symptoms 0.97 0.927 – 1.02 0.197 2042 20221 all phecode
772.1 Muscular wasting and disuse atrophy Symptoms 0.997 0.902 – 1.1 0.953 422 4199 all phecode
772.2 Spasm of muscle Symptoms 0.979 0.938 – 1.02 0.331 2299 22726 all phecode
772.3 Muscle weakness Symptoms 1 0.967 – 1.04 0.828 2949 28064 all phecode
772.4 Rhabdomyolysis Symptoms 1.09 0.923 – 1.29 0.313 159 1572 all phecode
772.6 Facial weakness Symptoms 0.999 0.908 – 1.1 0.98 478 4742 all phecode
780 Hypothermia/Chills Symptoms 1.03 0.934 – 1.14 0.546 453 4514 all phecode
781
Symptoms involving nervous and musculoskeletal
Symptoms involving nervous and musculoskeletal systems
 Symptoms 0.976 0.939 – 1.01 0.218 2822 26225 all phecode
781.1 Loss of height Symptoms 1.03 0.862 – 1.23 0.74 130 1269 all phecode
781.2 Abnormal posture Symptoms 0.902 0.696 – 1.17 0.436 57 567 all phecode
782.3 Edema Symptoms 0.984 0.957 – 1.01 0.263 5874 36788 all phecode
782.6 Pallor and flushing Symptoms 1.05 0.978 – 1.12 0.187 927 9252 all phecode
783 Fever of unknown origin Symptoms 1.02 0.989 – 1.05 0.239 5733 40720 all phecode
783.1 Postprocedural fever Symptoms 0.924 0.821 – 1.04 0.191 300 2992 all phecode
785 Abdominal pain Symptoms 0.987 0.968 – 1.01 0.172 16458 30297 all phecode
788 Syncope and collapse Symptoms 1.02 0.989 – 1.06 0.198 3851 35832 all phecode
789 Nausea and vomiting Symptoms 1.01 0.988 – 1.03 0.399 10568 36098 all phecode
789.1 Persistent vomiting Symptoms 0.981 0.912 – 1.05 0.599 798 7924 all phecode
790 Nonspecific findings on examination of blood Symptoms 1 0.961 – 1.05 0.906 2363 22690 all phecode
790.1 Elevated sedimentation rate Symptoms 1.1 0.961 – 1.26 0.165 236 2322 all phecode
790.6 Other abnormal blood chemistry Symptoms 1.02 0.991 – 1.04 0.196 7539 37788 all phecode
790.8 Elevated C-reactive protein (CRP) Symptoms 1.06 0.948 – 1.2 0.287 309 3075 all phecode
790.9 Abnormal arterial blood gases Symptoms 0.91 0.773 – 1.07 0.256 155 1521 all phecode
791 Gangrene Symptoms 0.981 0.872 – 1.1 0.748 313 3115 all phecode
792
Abnormal Papanicolaou smear of cervix and
Abnormal Papanicolaou smear of cervix and cervical HPV
 Genitourinary 0.979 0.94 – 1.02 0.313 2820 14872 all phecode
792.1
Papanicolaou smear of cervix or vagina with
Papanicolaou smear of cervix or vagina with atypical squamous cells
 Genitourinary 0.983 0.923 – 1.05 0.587 1100 9861 all phecode
794
Abnormal results of other function studies
Abnormal results of other function studies (bladder, pancreas, placenta, spleen, etc)
 Symptoms 1.05 0.959 – 1.15 0.282 515 5133 all phecode
795
Other and nonspecific abnormal cytological
Other and nonspecific abnormal cytological, histological and immunological findings
 Symptoms 0.978 0.936 – 1.02 0.331 2182 20242 all phecode
795.8 Abnormal tumor markers Symptoms 0.987 0.939 – 1.04 0.6 1745 15551 all phecode
795.81 Elevated carcinoembryonic antigen [CEA] Symptoms 1.03 0.792 – 1.34 0.821 61 605 all phecode
795.82 Elevated cancer antigen 125 [CA 125] Symptoms 1.02 0.876 – 1.18 0.83 201 2000 all phecode
796 Elevated prostate specific antigen [PSA] Genitourinary 0.975 0.93 – 1.02 0.297 2125 9930 all phecode
797 Shock Symptoms 1.03 0.945 – 1.12 0.535 605 6050 all phecode
797.1 Cardiogenic shock Symptoms 1.02 0.89 – 1.16 0.796 242 2420 all phecode
798 Malaise and fatigue Symptoms 1.02 0.994 – 1.04 0.157 11539 35196 all phecode
798.1 Chronic fatigue syndrome Symptoms 1 0.956 – 1.05 0.872 1823 17795 all phecode
800 Fracture of lower limb Injuries & Poisonings 0.996 0.954 – 1.04 0.853 2344 22951 all phecode
800.1 Fracture of neck of femur Injuries & Poisonings 0.976 0.893 – 1.07 0.599 512 4961 all phecode
800.2 Fracture of unspecified part of femur Injuries & Poisonings 0.988 0.914 – 1.07 0.767 670 6582 all phecode
800.3 Fracture of tibia and fibula Injuries & Poisonings 0.99 0.924 – 1.06 0.78 898 8966 all phecode
800.4 Fracture of patella Injuries & Poisonings 1.01 0.909 – 1.13 0.819 346 3456 all phecode
801 Fracture of ankle and foot Injuries & Poisonings 1 0.959 – 1.04 0.954 2358 22645 all phecode
801.1 Fracture of foot Injuries & Poisonings 1.01 0.953 – 1.08 0.685 1120 11178 all phecode
802 Fracture of pelvis Injuries & Poisonings 1.07 0.959 – 1.19 0.239 380 3765 all phecode
803 Fracture of upper limb Injuries & Poisonings 0.995 0.95 – 1.04 0.816 2051 20360 all phecode
803.1 Fracture of humerus Injuries & Poisonings 1.02 0.943 – 1.1 0.631 734 7322 all phecode
803.2 Fracture of radius and ulna Injuries & Poisonings 0.988 0.928 – 1.05 0.708 1112 11075 all phecode
803.21 Colles' fracture Injuries & Poisonings 1.02 0.901 – 1.15 0.794 291 2904 all phecode
803.3 Fracture of clavicle or scapula Injuries & Poisonings 0.977 0.892 – 1.07 0.61 514 5140 all phecode
804 Fracture of hand or wrist Injuries & Poisonings 1.02 0.966 – 1.07 0.521 1628 16042 all phecode
805
Fracture of vertebral column without mention of
Fracture of vertebral column without mention of spinal cord injury
 Injuries & Poisonings 1.02 0.965 – 1.08 0.46 1336 13242 all phecode
807 Fracture of ribs Injuries & Poisonings 1.03 0.949 – 1.11 0.518 683 6815 all phecode
809 Fracture of unspecified bones Injuries & Poisonings 0.999 0.961 – 1.04 0.947 2941 28633 all phecode
816 Cerebral laceration and contusion Injuries & Poisonings 0.731 0.555 – 0.963 0.0259 54 531 all phecode
817 Concussion Injuries & Poisonings 1.03 0.965 – 1.1 0.379 1018 10149 all phecode
818 Intracranial hemorrhage (injury) Injuries & Poisonings 0.95 0.847 – 1.07 0.383 311 3104 all phecode
818.1 Subdural hemorrhage (injury) Injuries & Poisonings 0.938 0.76 – 1.16 0.55 90 895 all phecode
818.2 Subarachnoid hemorrhage (injury) Injuries & Poisonings 1.06 0.869 – 1.3 0.545 97 970 all phecode
819
Skull and face fracture and other intercranial
Skull and face fracture and other intercranial injury
 Injuries & Poisonings 0.984 0.943 – 1.03 0.477 2287 22671 all phecode
830 Dislocation Injuries & Poisonings 1.02 0.983 – 1.05 0.349 3862 34720 all phecode
835 Internal derangement of knee Injuries & Poisonings 1.01 0.968 – 1.06 0.614 2231 21628 all phecode
836 Traumatic arthropathy Injuries & Poisonings 0.973 0.887 – 1.07 0.557 496 4954 all phecode
840 Sprains and strains Injuries & Poisonings 0.997 0.973 – 1.02 0.8 7838 37998 all phecode
840.1 Muscle/tendon sprain Injuries & Poisonings 1.01 0.926 – 1.11 0.787 537 5356 all phecode
840.2 Rotator cuff (capsule) sprain Injuries & Poisonings 0.981 0.932 – 1.03 0.458 1640 16263 all phecode
840.3 Joint/ligament sprain Injuries & Poisonings 0.991 0.953 – 1.03 0.644 2875 24879 all phecode
841 Sprains and strains of back and neck Injuries & Poisonings 0.977 0.928 – 1.03 0.381 1583 15592 all phecode
842 Other sprains and strains Injuries & Poisonings 1.02 0.961 – 1.07 0.566 1407 13924 all phecode
850 Hemorrhage or hematoma complicating a procedure Injuries & Poisonings 0.969 0.926 – 1.01 0.166 2072 20649 all phecode
851
Complications of transplants and reattached
Complications of transplants and reattached limbs
 Injuries & Poisonings 0.978 0.942 – 1.02 0.251 2982 27545 all phecode
853 Complication of colostomy or enterostomy Injuries & Poisonings 1.03 0.932 – 1.13 0.576 460 4600 all phecode
854
Complications of cardiac/vascular device
Complications of cardiac/vascular device, implant, and graft
 Injuries & Poisonings 1.03 0.986 – 1.08 0.175 1985 19675 all phecode
855
Complication of nervous system device, implant
Complication of nervous system device, implant, and graft
 Injuries & Poisonings 1.04 0.913 – 1.18 0.563 264 2640 all phecode
856
Vascular complications of surgery and medical
Vascular complications of surgery and medical procedures
 Injuries & Poisonings 0.983 0.872 – 1.11 0.776 293 2929 all phecode
857
Mechanical complication of unspecified
Mechanical complication of unspecified genitourinary device, implant, and graft
 Injuries & Poisonings 0.984 0.93 – 1.04 0.586 1310 13087 all phecode
858 Complication of internal orthopedic device Injuries & Poisonings 0.981 0.939 – 1.03 0.392 2213 21944 all phecode
859
Complication due to other implant and internal
Complication due to other implant and internal device
 Injuries & Poisonings 0.982 0.939 – 1.03 0.419 2110 21070 all phecode
860 Bone marrow or stem cell transplant Neoplasms 0.988 0.841 – 1.16 0.885 166 1660 all phecode
870 Open wounds of head; neck; and trunk Injuries & Poisonings 0.981 0.949 – 1.01 0.235 4117 36734 all phecode
870.1 Open wound or laceration of eye or eyelid Injuries & Poisonings 1.01 0.874 – 1.17 0.896 204 2026 all phecode
870.2 Open wound of ear Injuries & Poisonings 1.03 0.871 – 1.23 0.705 144 1437 all phecode
870.3 Other open wound of head and face Injuries & Poisonings 0.951 0.9 – 1.01 0.0829 1346 13301 all phecode
870.4 Open wound of nose and sinus Injuries & Poisonings 1.01 0.873 – 1.16 0.92 207 2057 all phecode
870.5 Open wound of lip and mouth Injuries & Poisonings 1 0.886 – 1.14 0.955 275 2724 all phecode
870.6 Open wound of neck Injuries & Poisonings 0.953 0.829 – 1.09 0.494 214 2128 all phecode
870.8 Open wound of genital organs Injuries & Poisonings 1.06 0.895 – 1.26 0.496 144 1440 all phecode
871 Open wounds of extremities Injuries & Poisonings 0.999 0.964 – 1.03 0.949 3530 32903 all phecode
871.1 Open wound of hand except finger(s) Injuries & Poisonings 0.993 0.91 – 1.08 0.866 572 5701 all phecode
871.2 Open wound of finger(s) Injuries & Poisonings 1.01 0.945 – 1.08 0.779 984 9772 all phecode
871.3 Open wound of foot except toe(s) alone Injuries & Poisonings 0.985 0.897 – 1.08 0.745 490 4843 all phecode
871.4 Open wound of toe(s) Injuries & Poisonings 1.04 0.925 – 1.17 0.504 295 2921 all phecode
872 Traumatic amputation Injuries & Poisonings 1.01 0.929 – 1.11 0.767 551 5477 all phecode
874 Complication of amputation stump Injuries & Poisonings 0.936 0.801 – 1.09 0.41 170 1697 all phecode
875 Non-healing surgical wound Injuries & Poisonings 0.959 0.879 – 1.05 0.35 572 5720 all phecode
876
Posttraumatic wound infection not elsewhere
Posttraumatic wound infection not elsewhere classified
 Injuries & Poisonings 0.995 0.926 – 1.07 0.899 802 8003 all phecode
907 Injuries to the nervous system Injuries & Poisonings 1.08 1.01 – 1.16 0.0162 1010 10096 all phecode
910 Superficial injury, infected Injuries & Poisonings 0.942 0.776 – 1.14 0.547 119 1161 all phecode
911 Blister Injuries & Poisonings 0.931 0.827 – 1.05 0.239 302 2996 all phecode
912 Insect bite Injuries & Poisonings 0.964 0.879 – 1.06 0.439 492 4886 all phecode
913 Toxic effect of venom Injuries & Poisonings 0.947 0.846 – 1.06 0.341 337 3326 all phecode
916 Contusion Injuries & Poisonings 1 0.969 – 1.03 0.995 4296 38033 all phecode
930 Allergic reaction to food Injuries & Poisonings 0.971 0.901 – 1.05 0.431 763 7596 all phecode
931
Contact dermatitis and other eczema due to
Contact dermatitis and other eczema due to plants [except food]
 Dermatologic 1 0.929 – 1.09 0.918 714 7072 all phecode
938 Dermatitis due to solar radiation Dermatologic 1.01 0.984 – 1.04 0.367 5567 29098 all phecode
938.1 Acute dermatitis due to solar radiation Dermatologic 0.991 0.862 – 1.14 0.9 217 2164 all phecode
938.2 Chronic dermatitis due to solar radiation Dermatologic 1.01 0.983 – 1.04 0.396 5307 28656 all phecode
939
Atopic/contact dermatitis due to other or
Atopic/contact dermatitis due to other or unspecified
 Dermatologic 1 0.975 – 1.03 0.896 6704 32389 all phecode
939.1 Contact and allergic dermatitis of eyelid Dermatologic 0.81 0.657 – 0.998 0.0481 91 870 all phecode
941 Adverse reaction to serum or vaccine Injuries & Poisonings 1.04 0.894 – 1.21 0.61 188 1880 all phecode
942 Infusion and transfusion reaction Injuries & Poisonings 1.01 0.889 – 1.15 0.884 269 2688 all phecode
946 Anaphylactic shock NOS Injuries & Poisonings 0.977 0.89 – 1.07 0.629 500 4940 all phecode
947 Urticaria Dermatologic 1.02 0.958 – 1.08 0.556 1177 11454 all phecode
949 Allergies, other Injuries & Poisonings 1 0.975 – 1.03 0.957 7251 32350 all phecode
952
Spinal cord injury without evidence of spinal
Spinal cord injury without evidence of spinal bone injury
 Injuries & Poisonings 1.1 1 – 1.21 0.0479 494 4940 all phecode
957 Injury to other and unspecified nerves Injuries & Poisonings 0.975 0.817 – 1.16 0.779 136 1352 all phecode
958
Certain early complications of trauma or
Certain early complications of trauma or procedure
 Injuries & Poisonings 0.993 0.935 – 1.05 0.81 1217 12158 all phecode
958.1 Postoperative shock Injuries & Poisonings 1.18 0.999 – 1.39 0.0514 169 1688 all phecode
958.2 Traumatic and surgical subcutaneous emphysema Injuries & Poisonings 1.12 0.925 – 1.35 0.25 114 1140 all phecode
960 Poisoning by antibiotics Injuries & Poisonings 0.969 0.929 – 1.01 0.138 2479 22087 all phecode
960.1
Adverse effects of antibacterials (not
Adverse effects of antibacterials (not penicillins)
 Injuries & Poisonings 1.01 0.904 – 1.13 0.87 342 3403 all phecode
960.2 Allergy/adverse effect of penicillin Injuries & Poisonings 0.975 0.927 – 1.03 0.338 1636 16005 all phecode
961 Poisoning by other anti-infectives Injuries & Poisonings 1.01 0.92 – 1.1 0.866 528 5234 all phecode
961.1 Poisoning/allergy of sulfonamides Injuries & Poisonings 0.956 0.898 – 1.02 0.164 1065 10347 all phecode
962 Poisoning by hormones and synthetic substitutes Injuries & Poisonings 0.999 0.928 – 1.07 0.971 803 7976 all phecode
962.1
Adrenal cortical steroids causing adverse
Adrenal cortical steroids causing adverse effects in therapeutic use
 Injuries & Poisonings 0.988 0.888 – 1.1 0.822 379 3782 all phecode
962.2
Insulins and antidiabetic agents causing
Insulins and antidiabetic agents causing adverse effects in therapeutic use
 Injuries & Poisonings 0.837 0.646 – 1.08 0.178 62 612 all phecode
962.3
Hormones and synthetic substitutes causing
Hormones and synthetic substitutes causing adverse effects in therapeutic use
 Injuries & Poisonings 1.01 0.92 – 1.11 0.819 478 4773 all phecode
963 Poisoning by primarily systemic agents Injuries & Poisonings 1.02 0.978 – 1.06 0.368 2533 24531 all phecode
963.1
Antineoplastic and immunosuppressive drugs
Antineoplastic and immunosuppressive drugs causing adverse effects
 Injuries & Poisonings 1.03 0.986 – 1.07 0.197 2469 24057 all phecode
964
Poisoning by agents primarily affecting blood
Poisoning by agents primarily affecting blood constituents
 Injuries & Poisonings 0.994 0.922 – 1.07 0.878 743 7337 all phecode
964.1 Anticoagulants causing adverse effects Injuries & Poisonings 0.985 0.912 – 1.06 0.69 712 7027 all phecode
965
Poisoning by analgesics, antipyretics, and
Poisoning by analgesics, antipyretics, and antirheumatics
 Injuries & Poisonings 1.04 0.971 – 1.12 0.247 864 8601 all phecode
965.1
Opiates and related narcotics causing adverse
Opiates and related narcotics causing adverse effects in therapeutic use
 Injuries & Poisonings 1.01 0.957 – 1.07 0.734 1469 14402 all phecode
965.3
Salicylates causing adverse effects in
Salicylates causing adverse effects in therapeutic use
 Injuries & Poisonings 1.1 0.91 – 1.32 0.331 119 1182 all phecode
966
Poisoning by anticonvulsants and
Poisoning by anticonvulsants and anti-Parkinsonism drugs
 Injuries & Poisonings 1.05 0.861 – 1.29 0.619 103 1006 all phecode
967
Adverse effects of sedatives or other central
Adverse effects of sedatives or other central nervous system depressants and anesthetics
 Injuries & Poisonings 0.975 0.92 – 1.03 0.401 1254 12464 all phecode
969 Poisoning by psychotropic agents Injuries & Poisonings 1.03 0.909 – 1.16 0.651 281 2797 all phecode
971
Poisoning by drugs primarily affecting the
Poisoning by drugs primarily affecting the autonomic nervous system
 Injuries & Poisonings 1 0.778 – 1.29 0.994 67 643 all phecode
972
Poisoning by agents primarily affecting the
Poisoning by agents primarily affecting the cardiovascular system
 Injuries & Poisonings 1 0.886 – 1.13 0.997 288 2858 all phecode
972.1
Cardiac rhythm regulators causing adverse
Cardiac rhythm regulators causing adverse effects in therapeutic use
 Injuries & Poisonings 1.14 0.896 – 1.44 0.29 80 776 all phecode
972.6 Antihypertensive agents causing adverse effects Injuries & Poisonings 0.828 0.679 – 1.01 0.0619 104 1034 all phecode
974
Poisoning by water, mineral, and uric acid
Poisoning by water, mineral, and uric acid metabolism drugs
 Injuries & Poisonings 1.07 0.88 – 1.29 0.511 113 1130 all phecode
975
Poisoning by agents primarily acting on the
Poisoning by agents primarily acting on the smooth and skeletal muscles and respiratory system
 Injuries & Poisonings 0.859 0.687 – 1.07 0.182 81 810 all phecode
976
Poisoning by agents primarily affecting skin &
Poisoning by agents primarily affecting skin & mucous membrane, ophthalmological, otorhinolaryngological, & dental drugs
 Injuries & Poisonings 1.27 0.985 – 1.64 0.0649 71 703 all phecode
977 Personal history of allergy to medicinal agents Injuries & Poisonings 0.969 0.922 – 1.02 0.204 1763 16599 all phecode
979 Adverse drug events and drug allergies Injuries & Poisonings 1.02 0.981 – 1.05 0.38 3448 30885 all phecode
980
Encounter for long-term (current) use of
Encounter for long-term (current) use of antibiotics
 Infectious Diseases 0.979 0.926 – 1.03 0.452 1391 13877 all phecode
985 Toxic effect of other metals Injuries & Poisonings 1.42 1.07 – 1.9 0.0164 57 564 all phecode
989
Toxic effect of other substances, chiefly
Toxic effect of other substances, chiefly nonmedicinal as to source
 Injuries & Poisonings 0.96 0.803 – 1.15 0.655 129 1275 all phecode
990 Effects radiation NOS Injuries & Poisonings 1.01 0.98 – 1.05 0.422 3927 31223 all phecode
994 Sepsis and SIRS Injuries & Poisonings 1.01 0.963 – 1.05 0.801 2192 21710 all phecode
994.1 Systemic inflammatory response syndrome (SIRS) Injuries & Poisonings 0.937 0.831 – 1.06 0.286 291 2910 all phecode
994.2 Sepsis Injuries & Poisonings 1.01 0.964 – 1.05 0.725 2086 20666 all phecode
994.21 Septic shock Injuries & Poisonings 0.97 0.894 – 1.05 0.462 627 6260 all phecode
008 Intestinal infection Infectious Diseases 0.993 0.933 – 1.06 0.819 1214 5969 exclusion phecode
008.5 Bacterial enteritis Infectious Diseases 1.05 0.951 – 1.15 0.35 510 2623 exclusion phecode
008.52 Intestinal infection due to C. difficile Infectious Diseases 1.07 0.962 – 1.2 0.201 397 2047 exclusion phecode
008.6 Viral Enteritis Infectious Diseases 0.972 0.864 – 1.09 0.632 359 1633 exclusion phecode
010 Tuberculosis Infectious Diseases 1.19 0.934 – 1.51 0.16 80 466 exclusion phecode
031 Diseases due to other mycobacteria Infectious Diseases 0.807 0.572 – 1.14 0.221 40 184 exclusion phecode
038 Septicemia Infectious Diseases 1.07 1 – 1.15 0.0356 1053 4659 exclusion phecode
038.1 Gram negative septicemia Infectious Diseases 1.05 0.922 – 1.2 0.45 276 1157 exclusion phecode
038.2 Gram positive septicemia Infectious Diseases 0.924 0.733 – 1.16 0.501 106 482 exclusion phecode
038.3 Bacteremia Infectious Diseases 1.06 0.965 – 1.16 0.227 573 2429 exclusion phecode
041 Bacterial infection NOS Infectious Diseases 1.04 0.991 – 1.1 0.111 2016 7043 exclusion phecode
041.1 Staphylococcus infections Infectious Diseases 1.04 0.951 – 1.14 0.393 588 3190 exclusion phecode
041.11 Methicillin sensitive Staphylococcus aureus Infectious Diseases 1.05 0.936 – 1.18 0.4 362 1830 exclusion phecode
041.12 Methicillin resistant Staphylococcus aureus Infectious Diseases 1.04 0.908 – 1.19 0.559 256 1459 exclusion phecode
041.2 Streptococcus infection Infectious Diseases 1 0.921 – 1.09 0.948 660 3108 exclusion phecode
041.21 Rheumatic fever / chorea Infectious Diseases 1.08 0.851 – 1.37 0.529 77 495 exclusion phecode
041.4 E. coli Infectious Diseases 1.07 0.973 – 1.19 0.153 481 2254 exclusion phecode
041.8 H. pylori Infectious Diseases 0.806 0.634 – 1.03 0.0791 84 501 exclusion phecode
041.9 Infection with drug-resistant microorganisms Infectious Diseases 1.09 0.916 – 1.29 0.341 167 713 exclusion phecode
053 Herpes zoster Infectious Diseases 0.95 0.871 – 1.04 0.249 635 2754 exclusion phecode
053.1 Herpes zoster with nervous system complications Infectious Diseases 0.866 0.683 – 1.1 0.232 89 383 exclusion phecode
054 Herpes simplex Infectious Diseases 0.985 0.898 – 1.08 0.741 542 2601 exclusion phecode
070 Viral hepatitis Infectious Diseases 0.934 0.819 – 1.06 0.301 269 1416 exclusion phecode
070.1 Viral hepatitis A Infectious Diseases 0.689 0.435 – 1.09 0.113 22 157 exclusion phecode
070.2 Viral hepatitis B Infectious Diseases 0.893 0.687 – 1.16 0.4 69 338 exclusion phecode
070.3 Viral hepatitis C Infectious Diseases 0.928 0.792 – 1.09 0.353 179 886 exclusion phecode
070.4 Chronic hepatitis Infectious Diseases 1.11 0.874 – 1.41 0.389 87 339 exclusion phecode
070.9 Hepatitis NOS Infectious Diseases 0.97 0.867 – 1.09 0.593 355 1924 exclusion phecode
071 Human immunodeficiency virus [HIV] disease Infectious Diseases 1.22 0.906 – 1.65 0.189 58 266 exclusion phecode
071.1 HIV infection, symptomatic Infectious Diseases 1.37 0.965 – 1.94 0.0784 48 209 exclusion phecode
078 Viral warts & HPV Infectious Diseases 0.99 0.931 – 1.05 0.748 1270 4660 exclusion phecode
079 Viral infection Infectious Diseases 1.01 0.968 – 1.06 0.545 2623 5564 exclusion phecode
079.1 Varicella infection Infectious Diseases 0.982 0.926 – 1.04 0.546 1417 5081 exclusion phecode
079.2 Infectious mononucleosis Infectious Diseases 1.11 0.867 – 1.42 0.411 83 420 exclusion phecode
079.9 Viremia, NOS Infectious Diseases 1.11 0.984 – 1.24 0.0903 402 1449 exclusion phecode
080 Postoperative infection Infectious Diseases 1 0.927 – 1.08 0.955 735 4968 exclusion phecode
081
Infection/inflammation of internal prosthetic
Infection/inflammation of internal prosthetic device; implant; and graft
 Infectious Diseases 1.05 0.958 – 1.16 0.279 508 3016 exclusion phecode
090
Sexually transmitted infections (not HIV or
Sexually transmitted infections (not HIV or hepatitis)
 Infectious Diseases 1.18 1.05 – 1.31 0.00473 364 2162 exclusion phecode
110 Dermatophytosis / Dermatomycosis Infectious Diseases 0.99 0.937 – 1.05 0.716 1708 5487 exclusion phecode
110.1 Dermatophytosis Infectious Diseases 0.979 0.925 – 1.04 0.469 1602 5067 exclusion phecode
110.11 Dermatophytosis of nail Infectious Diseases 1 0.937 – 1.07 0.923 1103 3455 exclusion phecode
110.12 Althete's foot Infectious Diseases 1.06 0.953 – 1.17 0.293 468 1839 exclusion phecode
110.13 Dermatophytosis of the body Infectious Diseases 0.98 0.869 – 1.1 0.737 340 1572 exclusion phecode
110.2 Dermatomycoses Infectious Diseases 1.03 0.864 – 1.22 0.761 153 785 exclusion phecode
112 Candidiasis Infectious Diseases 1.08 1.01 – 1.15 0.0158 1296 5197 exclusion phecode
112.3 Candidiasis of skin and nails Infectious Diseases 0.947 0.833 – 1.08 0.41 269 1195 exclusion phecode
117 Mycoses Infectious Diseases 1.03 0.882 – 1.19 0.746 212 1115 exclusion phecode
117.1 Histoplasmosis Infectious Diseases 0.937 0.599 – 1.47 0.775 20 160 exclusion phecode
117.4 Aspergillosis Infectious Diseases 1.08 0.794 – 1.47 0.627 55 271 exclusion phecode
130 Spirochetal infection Infectious Diseases 0.969 0.738 – 1.27 0.82 60 301 exclusion phecode
130.1 Lyme disease Infectious Diseases 1.07 0.757 – 1.5 0.718 38 203 exclusion phecode
131 Protozoan infection Infectious Diseases 0.611 0.358 – 1.04 0.0714 17 109 exclusion phecode
132 Infestation (lice, mites) Infectious Diseases 0.775 0.617 – 0.974 0.0289 73 401 exclusion phecode
134 Helminthiases Infectious Diseases 0.904 0.622 – 1.31 0.599 31 156 exclusion phecode
134.1 Intestinal helminthiases Infectious Diseases 0.829 0.494 – 1.39 0.477 18 114 exclusion phecode
136 Other infectious and parasitic diseases Infectious Diseases 1 0.939 – 1.07 0.972 1123 6410 exclusion phecode
145 Cancer of mouth Neoplasms 0.852 0.733 – 0.99 0.0359 176 2974 exclusion phecode
145.1 Cancer of lip Neoplasms 0.835 0.407 – 1.71 0.624 9 130 exclusion phecode
145.2 Cancer of tongue Neoplasms 0.713 0.557 – 0.912 0.00719 65 1291 exclusion phecode
145.3 Cancer of major salivary glands Neoplasms 0.925 0.703 – 1.22 0.581 54 741 exclusion phecode
145.4 Cancer of the gums Neoplasms 0.477 0.264 – 0.863 0.0144 12 321 exclusion phecode
145.5 Cancer of the mouth floor Neoplasms 1 0.659 – 1.53 0.987 18 383 exclusion phecode
149 Cancer of larynx, pharynx, nasal cavities Neoplasms 0.864 0.737 – 1.01 0.0715 152 2619 exclusion phecode
149.1 Cancer of oropharynx Neoplasms 0.904 0.688 – 1.19 0.469 53 746 exclusion phecode
149.2 Cancer of nasopharynx Neoplasms 1.18 0.681 – 2.03 0.559 13 204 exclusion phecode
149.3 Cancer of hypopharynx Neoplasms 1.15 0.621 – 2.15 0.65 8 177 exclusion phecode
149.4 Cancer of larynx Neoplasms 0.686 0.506 – 0.931 0.0155 42 796 exclusion phecode
149.5
Hx of malignant neoplasm of oral cavity and
Hx of malignant neoplasm of oral cavity and pharynx
 Neoplasms 0.828 0.67 – 1.02 0.0822 85 1120 exclusion phecode
149.9 Cancer of of nasal cavities Neoplasms 1.16 0.778 – 1.73 0.466 23 467 exclusion phecode
150 Cancer of esophagus Neoplasms 1.01 0.789 – 1.29 0.955 69 805 exclusion phecode
151 Cancer of stomach Neoplasms 1.09 0.881 – 1.35 0.431 93 960 exclusion phecode
153 Colorectal cancer Neoplasms 1.03 0.918 – 1.16 0.609 344 2154 exclusion phecode
153.2 Colon cancer Neoplasms 1.06 0.928 – 1.2 0.411 278 1712 exclusion phecode
153.3
Malignant neoplasm of rectum, rectosigmoid
Malignant neoplasm of rectum, rectosigmoid junction, and anus
 Neoplasms 1.02 0.87 – 1.19 0.849 186 1173 exclusion phecode
155 Cancer of liver and intrahepatic bile duct Neoplasms 1.18 0.973 – 1.44 0.0919 119 908 exclusion phecode
155.1 Malignant neoplasm of liver, primary Neoplasms 1.12 0.891 – 1.42 0.327 89 643 exclusion phecode
157 Pancreatic cancer Neoplasms 1.03 0.841 – 1.26 0.772 105 933 exclusion phecode
158
Neoplasm of unspecified nature of digestive
Neoplasm of unspecified nature of digestive system
 Neoplasms 0.952 0.866 – 1.05 0.312 505 3056 exclusion phecode
159
Malignant neoplasm of other and ill-defined
Malignant neoplasm of other and ill-defined sites within the digestive organs and peritoneum
 Neoplasms 1.04 0.942 – 1.15 0.427 440 3215 exclusion phecode
159.2
Malignant neoplasm of small intestine
Malignant neoplasm of small intestine, including duodenum
 Neoplasms 1.05 0.777 – 1.43 0.743 45 409 exclusion phecode
159.3
Malignant neoplasm of gallbladder and
Malignant neoplasm of gallbladder and extrahepatic bile ducts
 Neoplasms 0.981 0.649 – 1.48 0.929 22 330 exclusion phecode
159.4
Malignant neoplasm of retroperitoneum and
Malignant neoplasm of retroperitoneum and peritoneum
 Neoplasms 0.945 0.735 – 1.22 0.659 61 497 exclusion phecode
164 Cancer of intrathoracic organs Neoplasms 0.966 0.697 – 1.34 0.836 32 266 exclusion phecode
165 Cancer within the respiratory system Neoplasms 0.963 0.848 – 1.09 0.562 267 2696 exclusion phecode
165.1 Cancer of bronchus; lung Neoplasms 0.957 0.836 – 1.09 0.52 238 2162 exclusion phecode
170 Cancer of bone and connective tissue Neoplasms 0.906 0.793 – 1.04 0.148 224 3471 exclusion phecode
170.1 Bone cancer Neoplasms 0.865 0.706 – 1.06 0.159 99 1447 exclusion phecode
170.2 Cancer of connective tissue Neoplasms 0.909 0.777 – 1.06 0.238 157 2411 exclusion phecode
172 Skin cancer Neoplasms 0.966 0.915 – 1.02 0.211 1821 6592 exclusion phecode
172.1 Melanomas of skin, dx or hx Neoplasms 0.954 0.896 – 1.02 0.15 1220 5962 exclusion phecode
172.11 Melanomas of skin Neoplasms 0.886 0.802 – 0.979 0.0173 415 4893 exclusion phecode
172.2 Other non-epithelial cancer of skin Neoplasms 0.957 0.904 – 1.01 0.135 1641 6121 exclusion phecode
172.21 Basal cell carcinoma Neoplasms 0.984 0.918 – 1.05 0.647 1011 4915 exclusion phecode
172.22 Squamous cell carcinoma Neoplasms 0.996 0.912 – 1.09 0.924 603 3747 exclusion phecode
172.3 Carcinoma in situ of skin Neoplasms 1.01 0.908 – 1.11 0.912 426 2789 exclusion phecode
173 Neoplasm of uncertain behavior of skin Neoplasms 0.984 0.905 – 1.07 0.707 645 4064 exclusion phecode
174 Breast cancer Neoplasms 0.986 0.904 – 1.08 0.753 644 2590 exclusion phecode
174.1 Breast cancer [female] Neoplasms 0.991 0.906 – 1.09 0.853 605 2403 exclusion phecode
174.11 Malignant neoplasm of female breast Neoplasms 1 0.912 – 1.1 0.995 592 2376 exclusion phecode
174.3 Neoplasm of uncertain behavior of breast Neoplasms 1.14 0.881 – 1.48 0.316 54 391 exclusion phecode
175 Acquired absence of breast Neoplasms 1.09 0.93 – 1.28 0.288 182 1160 exclusion phecode
180 Cervical cancer and dysplasia Neoplasms 0.993 0.886 – 1.11 0.909 357 1919 exclusion phecode
180.1 Cervical cancer Neoplasms 0.963 0.768 – 1.21 0.744 74 719 exclusion phecode
180.3
Cervical intraepithelial neoplasia [CIN]
Cervical intraepithelial neoplasia [CIN] [Cervical dysplasia]
 Neoplasms 0.988 0.871 – 1.12 0.85 307 1441 exclusion phecode
182 Malignant neoplasm of uterus Neoplasms 0.922 0.775 – 1.1 0.364 133 1214 exclusion phecode
184 Cancer of other female genital organs Neoplasms 0.997 0.876 – 1.13 0.965 243 2012 exclusion phecode
184.1
Malignant neoplasm of ovary and other uterine
Malignant neoplasm of ovary and other uterine adnexa
 Neoplasms 0.966 0.796 – 1.17 0.726 102 982 exclusion phecode
184.11 Malignant neoplasm of ovary Neoplasms 0.933 0.745 – 1.17 0.541 74 734 exclusion phecode
184.2
Cancer of other female genital organs
Cancer of other female genital organs (excluding uterus and ovary)
 Neoplasms 1 0.846 – 1.18 0.997 145 1084 exclusion phecode
185 Cancer of prostate Neoplasms 0.949 0.857 – 1.05 0.321 542 2021 exclusion phecode
187 Cancer of other male genital organs Neoplasms 1.13 0.888 – 1.43 0.329 75 724 exclusion phecode
187.1
Malignant neoplasm of unspecified male genital
Malignant neoplasm of unspecified male genital organ
 Neoplasms 1.08 0.69 – 1.69 0.739 21 249 exclusion phecode
187.2 Malignant neoplasm of testis Neoplasms 1.29 0.918 – 1.81 0.142 36 355 exclusion phecode
187.8
Neoplasm of uncertain behavior of male genital
Neoplasm of uncertain behavior of male genital organs
 Neoplasms 1 0.661 – 1.53 0.985 24 138 exclusion phecode
189
Cancer of urinary organs (incl. kidney and
Cancer of urinary organs (incl. kidney and bladder)
 Neoplasms 1.06 0.971 – 1.16 0.187 564 4858 exclusion phecode
189.1 Cancer of kidney and renal pelvis Neoplasms 0.973 0.861 – 1.1 0.656 272 3046 exclusion phecode
189.11 Malignant neoplasm of kidney, except pelvis Neoplasms 0.98 0.857 – 1.12 0.772 229 2649 exclusion phecode
189.12 Malignant neoplasm of renal pelvis Neoplasms 0.895 0.67 – 1.2 0.451 45 541 exclusion phecode
189.2 Cancer of bladder Neoplasms 1.13 1.01 – 1.26 0.0395 354 3303 exclusion phecode
189.21 Malignant neoplasm of bladder Neoplasms 1.12 0.992 – 1.26 0.0675 313 3088 exclusion phecode
189.4 Malignant neoplasm of other urinary organs Neoplasms 1.18 0.988 – 1.42 0.0677 132 1446 exclusion phecode
190 Cancer of eye Neoplasms 0.831 0.56 – 1.23 0.358 25 269 exclusion phecode
191
Manlignant and unknown neoplasms of brain and
Manlignant and unknown neoplasms of brain and nervous system
 Neoplasms 0.978 0.833 – 1.15 0.791 156 1935 exclusion phecode
191.1 Cancer of brain and nervous system Neoplasms 0.967 0.792 – 1.18 0.743 92 1242 exclusion phecode
191.11 Cancer of brain Neoplasms 0.962 0.767 – 1.21 0.739 73 1025 exclusion phecode
193 Thyroid cancer Neoplasms 1.04 0.883 – 1.22 0.658 162 1804 exclusion phecode
194 Cancer of other endocrine glands Neoplasms 1.1 0.91 – 1.33 0.322 121 1191 exclusion phecode
195 Cancer, suspected or other Neoplasms 1.02 0.97 – 1.06 0.497 3427 5196 exclusion phecode
195.1 Malignant neoplasm, other Neoplasms 1.01 0.968 – 1.06 0.551 3391 5188 exclusion phecode
195.3 Malignant neoplasm of head, face, and neck Neoplasms 0.888 0.761 – 1.04 0.129 168 1912 exclusion phecode
196 Radiotherapy Neoplasms 0.978 0.893 – 1.07 0.638 550 3273 exclusion phecode
197 Chemotherapy Neoplasms 1.05 0.977 – 1.12 0.19 1033 4586 exclusion phecode
198 Secondary malignant neoplasm Neoplasms 1.03 0.956 – 1.11 0.432 866 4413 exclusion phecode
198.1 Secondary malignancy of lymph nodes Neoplasms 1.05 0.959 – 1.16 0.273 482 3986 exclusion phecode
198.2 Secondary malignancy of respiratory organs Neoplasms 0.967 0.832 – 1.12 0.664 187 1946 exclusion phecode
198.3
Secondary malignant neoplasm of digestive
Secondary malignant neoplasm of digestive systems
 Neoplasms 0.986 0.836 – 1.16 0.862 151 1569 exclusion phecode
198.4 Secondary malignant neoplasm of liver Neoplasms 1.05 0.882 – 1.25 0.585 134 1459 exclusion phecode
198.5 Secondary malignancy of brain/spine Neoplasms 0.957 0.774 – 1.18 0.682 89 1150 exclusion phecode
198.6 Secondary malignancy of bone Neoplasms 1.1 0.932 – 1.29 0.265 161 1559 exclusion phecode
198.7 Secondary malignant neoplasm of skin Neoplasms 0.784 0.602 – 1.02 0.0703 52 691 exclusion phecode
199 Neoplasm of uncertain behavior Neoplasms 1.02 0.957 – 1.08 0.571 1372 5086 exclusion phecode
199.4 Neurofibromatosis Neoplasms 1.04 0.595 – 1.81 0.896 11 156 exclusion phecode
200 Myeloproliferative disease Neoplasms 1.02 0.919 – 1.13 0.72 441 2412 exclusion phecode
200.1 Polycythemia vera Neoplasms 1.02 0.832 – 1.24 0.867 117 527 exclusion phecode
201 Hodgkin's disease Neoplasms 0.939 0.715 – 1.23 0.649 57 345 exclusion phecode
202 Cancer of other lymphoid, histiocytic tissue Neoplasms 0.965 0.866 – 1.08 0.524 378 3215 exclusion phecode
202.2 Non-Hodgkins lymphoma Neoplasms 0.945 0.84 – 1.06 0.353 314 2764 exclusion phecode
202.21 Nodular lymphoma Neoplasms 0.871 0.742 – 1.02 0.0919 158 1411 exclusion phecode
202.22 Reticulosarcoma Neoplasms 1.09 0.785 – 1.51 0.607 43 375 exclusion phecode
202.24 Large cell lymphoma Neoplasms 1.3 0.917 – 1.85 0.141 36 342 exclusion phecode
204 Leukemia Neoplasms 1.05 0.916 – 1.21 0.47 240 1578 exclusion phecode
204.1 Lymphoid leukemia Neoplasms 0.991 0.761 – 1.29 0.944 63 517 exclusion phecode
204.11 Lymphoid leukemia, acute Neoplasms 0.885 0.569 – 1.38 0.586 27 158 exclusion phecode
204.12 Lymphoid leukemia, chronic Neoplasms 1.04 0.773 – 1.41 0.782 46 386 exclusion phecode
204.2 Myeloid leukemia Neoplasms 1.1 0.895 – 1.36 0.357 121 663 exclusion phecode
204.21 Myeloid leukemia, acute Neoplasms 1.07 0.814 – 1.41 0.619 72 389 exclusion phecode
204.22 Myeloid leukemia, chronic Neoplasms 1.3 0.791 – 2.14 0.299 23 135 exclusion phecode
204.4 Multiple myeloma Neoplasms 0.923 0.727 – 1.17 0.512 77 503 exclusion phecode
208 Benign neoplasm of colon Neoplasms 0.979 0.938 – 1.02 0.339 3725 5595 exclusion phecode
209 Neuroendocrine tumors Neoplasms 1.08 0.834 – 1.39 0.565 63 546 exclusion phecode
210 Benign neoplasm of lip, oral cavity, and pharynx Neoplasms 0.918 0.816 – 1.03 0.158 295 3630 exclusion phecode
211
Benign neoplasm of other parts of digestive
Benign neoplasm of other parts of digestive system
 Neoplasms 0.991 0.946 – 1.04 0.691 2509 6533 exclusion phecode
212
Benign neoplasm of respiratory and
Benign neoplasm of respiratory and intrathoracic organs
 Neoplasms 1.04 0.937 – 1.16 0.457 391 3505 exclusion phecode
213 Benign neoplasm of bone and articular cartilage Neoplasms 0.907 0.806 – 1.02 0.107 332 2266 exclusion phecode
214 Lipoma Neoplasms 1.06 0.958 – 1.17 0.255 459 2915 exclusion phecode
214.1 Lipoma of skin and subcutaneous tissue Neoplasms 1.04 0.91 – 1.18 0.594 280 1774 exclusion phecode
215
Other benign neoplasm of connective and other
Other benign neoplasm of connective and other soft tissue
 Neoplasms 0.977 0.916 – 1.04 0.482 1054 7625 exclusion phecode
216 Benign neoplasm of skin Neoplasms 0.967 0.927 – 1.01 0.113 3606 5974 exclusion phecode
216.1 Screening for malignant neoplasms of the skin Neoplasms 0.683 0.522 – 0.895 0.00569 68 309 exclusion phecode
217 Vascular hamartomas and non-neoplastic nevi Neoplasms 0.926 0.85 – 1.01 0.0802 645 3218 exclusion phecode
217.1 Nevus, non-neoplastic Neoplasms 0.923 0.847 – 1.01 0.0712 623 3080 exclusion phecode
218 Benign neoplasm of uterus Neoplasms 0.895 0.836 – 0.958 0.00145 1199 2769 exclusion phecode
218.1 Uterine leiomyoma Neoplasms 0.812 0.738 – 0.894 2.22e-05 494 2563 exclusion phecode
218.2 Other benign neoplasm of uterus Neoplasms 0.885 0.822 – 0.954 0.00132 967 2696 exclusion phecode
220 Benign neoplasm of ovary Neoplasms 0.941 0.814 – 1.09 0.411 206 1249 exclusion phecode
221 Benign neoplasm of other female genital organs Neoplasms 0.908 0.82 – 1 0.0614 445 2224 exclusion phecode
222 Benign neoplasm of male genital organs Neoplasms 0.953 0.844 – 1.08 0.443 297 2486 exclusion phecode
223
Benign neoplasm of kidney and other urinary
Benign neoplasm of kidney and other urinary organs
 Neoplasms 1.03 0.921 – 1.16 0.564 370 1867 exclusion phecode
224 Benign neoplasm of eye Neoplasms 0.947 0.835 – 1.08 0.403 283 1709 exclusion phecode
224.1 Benign neoplasm of eye, uveal Neoplasms 0.97 0.849 – 1.11 0.655 257 1504 exclusion phecode
225
Benign neoplasm of brain and other parts of
Benign neoplasm of brain and other parts of nervous system
 Neoplasms 0.949 0.823 – 1.1 0.474 204 2269 exclusion phecode
225.1
Benign neoplasm of brain, cranial nerves
Benign neoplasm of brain, cranial nerves, meninges
 Neoplasms 1.03 0.869 – 1.22 0.729 145 1751 exclusion phecode
225.2 Benign neoplasm of spinal cord, meninges Neoplasms 0.811 0.622 – 1.06 0.125 58 537 exclusion phecode
226 Benign neoplasm of thyroid glands Neoplasms 1.02 0.907 – 1.14 0.769 312 2658 exclusion phecode
227
Benign neoplasm of other endocrine glands and
Benign neoplasm of other endocrine glands and related structures
 Neoplasms 1.03 0.921 – 1.16 0.582 327 3275 exclusion phecode
227.1 Benign neoplasm of adrenal gland Neoplasms 1.19 0.987 – 1.42 0.0686 137 1018 exclusion phecode
227.2 Benign neoplasm of parathyroid gland Neoplasms 1.06 0.887 – 1.27 0.517 133 1391 exclusion phecode
227.3
Benign neoplasm of pituitary gland and
Benign neoplasm of pituitary gland and craniopharyngeal duct (pouch)
 Neoplasms 0.925 0.719 – 1.19 0.542 63 870 exclusion phecode
228 Hemangioma and lymphangioma, any site Neoplasms 0.938 0.867 – 1.02 0.113 709 4626 exclusion phecode
228.1 Hemangioma of skin and subcutaneous tissue Neoplasms 0.906 0.825 – 0.996 0.0419 494 3047 exclusion phecode
229 Benign neoplasm of unspecified sites Neoplasms 1 0.945 – 1.07 0.89 1244 7465 exclusion phecode
229.1 Benign neoplasm of lymph nodes Neoplasms 1.02 0.947 – 1.11 0.563 724 6719 exclusion phecode
240 Simple and unspecified goiter Endocrine/metabolic 1.07 0.958 – 1.21 0.22 337 2007 exclusion phecode
241 Nontoxic nodular goiter Endocrine/metabolic 1.03 0.953 – 1.11 0.485 828 4383 exclusion phecode
241.1 Nontoxic uninodular goiter Endocrine/metabolic 1.01 0.934 – 1.1 0.736 663 3845 exclusion phecode
241.2 Nontoxic multinodular goiter Endocrine/metabolic 1.07 0.957 – 1.19 0.246 383 2424 exclusion phecode
242 Thyrotoxicosis with or without goiter Endocrine/metabolic 1.01 0.92 – 1.12 0.771 466 2750 exclusion phecode
242.1 Graves' disease Endocrine/metabolic 0.974 0.815 – 1.16 0.774 137 1024 exclusion phecode
242.2 Toxic multinodular goiter Endocrine/metabolic 1.36 0.947 – 1.96 0.0955 36 262 exclusion phecode
242.3 Exophthalmos Endocrine/metabolic 1.22 0.952 – 1.56 0.118 79 577 exclusion phecode
242.31 Thyrotoxic exophthalmos Endocrine/metabolic 0.834 0.57 – 1.22 0.351 33 262 exclusion phecode
244 Hypothyroidism Endocrine/metabolic 1.01 0.96 – 1.06 0.683 2072 6377 exclusion phecode
244.1 Secondary hypothyroidism Endocrine/metabolic 1.02 0.922 – 1.13 0.665 402 3305 exclusion phecode
244.2 Acquired hypothyroidism Endocrine/metabolic 1.16 1.05 – 1.28 0.00421 441 2531 exclusion phecode
244.4 Hypothyroidism NOS Endocrine/metabolic 1.01 0.957 – 1.06 0.768 1995 6295 exclusion phecode
245 Thyroiditis Endocrine/metabolic 1.07 0.94 – 1.22 0.306 260 1745 exclusion phecode
245.2 Chronic thyroiditis Endocrine/metabolic 1.06 0.923 – 1.23 0.394 217 1448 exclusion phecode
245.21 Chronic lymphocytic thyroiditis Endocrine/metabolic 1.05 0.91 – 1.21 0.501 216 1447 exclusion phecode
246 Other disorders of thyroid Endocrine/metabolic 0.975 0.92 – 1.03 0.402 1482 5893 exclusion phecode
246.2 Thyroid cyst Endocrine/metabolic 0.824 0.559 – 1.21 0.329 31 197 exclusion phecode
246.7 Abnormal results of function study of thyroid Endocrine/metabolic 1.06 0.95 – 1.19 0.289 354 1926 exclusion phecode
249 Secondary diabetes mellitus Endocrine/metabolic 1.01 0.908 – 1.12 0.846 691 1087 exclusion phecode
250 Diabetes mellitus Endocrine/metabolic 1.04 0.994 – 1.09 0.0914 5139 4378 exclusion phecode
250.1 Type 1 diabetes Endocrine/metabolic 1.06 0.966 – 1.16 0.233 1559 1539 exclusion phecode
250.11 Type 1 diabetes with ketoacidosis Endocrine/metabolic 0.984 0.768 – 1.26 0.9 175 146 exclusion phecode
250.12 Type 1 diabetes with renal manifestations Endocrine/metabolic 0.971 0.821 – 1.15 0.735 391 391 exclusion phecode
250.13 Type 1 diabetes with ophthalmic manifestations Endocrine/metabolic 1.09 0.935 – 1.28 0.261 566 411 exclusion phecode
250.14 Type 1 diabetes with neurological manifestations Endocrine/metabolic 1.11 0.944 – 1.31 0.203 462 364 exclusion phecode
250.15
Diabetes type 1 with peripheral circulatory
Diabetes type 1 with peripheral circulatory disorders
 Endocrine/metabolic 0.938 0.697 – 1.26 0.675 123 117 exclusion phecode
250.2 Type 2 diabetes Endocrine/metabolic 1.07 1.01 – 1.12 0.0175 3804 4047 exclusion phecode
250.21 Type 2 diabetes with ketoacidosis Endocrine/metabolic 1.05 0.835 – 1.33 0.656 181 181 exclusion phecode
250.22 Type 2 diabetes with renal manifestations Endocrine/metabolic 1.11 1.02 – 1.21 0.0138 1254 1797 exclusion phecode
250.23 Type 2 diabetes with ophthalmic manifestations Endocrine/metabolic 0.999 0.909 – 1.1 0.975 1123 1301 exclusion phecode
250.24 Type 2 diabetes with neurological manifestations Endocrine/metabolic 1.06 0.984 – 1.15 0.124 1590 2173 exclusion phecode
250.25
Diabetes type 2 with peripheral circulatory
Diabetes type 2 with peripheral circulatory disorders
 Endocrine/metabolic 1.06 0.94 – 1.19 0.357 593 876 exclusion phecode
250.3 Insulin pump user Endocrine/metabolic 1.1 1.03 – 1.18 0.00557 2021 2716 exclusion phecode
250.4 Abnormal glucose Endocrine/metabolic 1.02 0.975 – 1.08 0.347 3800 4234 exclusion phecode
250.41 Impaired fasting glucose Endocrine/metabolic 0.997 0.917 – 1.08 0.947 833 2258 exclusion phecode
250.42 Other abnormal glucose Endocrine/metabolic 1.03 0.977 – 1.08 0.287 3471 4153 exclusion phecode
250.5 Glycosuria or Acetonuria Endocrine/metabolic 1.15 0.804 – 1.66 0.438 63 166 exclusion phecode
250.6 Polyneuropathy in diabetes Endocrine/metabolic 1.05 0.964 – 1.14 0.272 1388 1776 exclusion phecode
250.7 Diabetic retinopathy Endocrine/metabolic 1.01 0.934 – 1.08 0.867 1153 2114 exclusion phecode
251 Other disorders of pancreatic internal secretion Endocrine/metabolic 1.03 0.933 – 1.14 0.57 510 1961 exclusion phecode
251.1 Hypoglycemia Endocrine/metabolic 1.09 0.978 – 1.23 0.114 653 1107 exclusion phecode
252 Disorders of parathyroid gland Endocrine/metabolic 1.06 0.979 – 1.14 0.157 752 3989 exclusion phecode
252.1 Hyperparathyroidism Endocrine/metabolic 1.07 0.991 – 1.17 0.0817 702 3700 exclusion phecode
252.2 Hypoparathyroidism Endocrine/metabolic 1.1 0.915 – 1.31 0.318 136 871 exclusion phecode
253
Disorders of the pituitary gland and its
Disorders of the pituitary gland and its hypothalamic control
 Endocrine/metabolic 0.999 0.874 – 1.14 0.986 242 1739 exclusion phecode
253.1 Pituitary hyperfunction Endocrine/metabolic 1.03 0.805 – 1.33 0.796 69 537 exclusion phecode
253.11 Acromegaly and gigantism Endocrine/metabolic 1.39 0.79 – 2.44 0.254 12 144 exclusion phecode
253.2 Pituitary hypofunction Endocrine/metabolic 1.09 0.813 – 1.46 0.563 45 419 exclusion phecode
253.3 Diabetes insipidus Endocrine/metabolic 0.949 0.65 – 1.39 0.788 33 191 exclusion phecode
253.4 Anterior pituitary disorders Endocrine/metabolic 0.751 0.541 – 1.04 0.0864 48 309 exclusion phecode
253.7 Other disorders of neurohypophysis Endocrine/metabolic 1.05 0.782 – 1.4 0.756 40 201 exclusion phecode
255 Disorders of adrenal glands Endocrine/metabolic 1.03 0.934 – 1.14 0.545 459 2954 exclusion phecode
255.1 Adrenal hyperfunction Endocrine/metabolic 1.01 0.839 – 1.21 0.919 118 715 exclusion phecode
255.11 Cushing's syndrome Endocrine/metabolic 1.06 0.798 – 1.41 0.69 48 361 exclusion phecode
255.12 Hyperaldosteronism Endocrine/metabolic 1.01 0.732 – 1.39 0.955 42 270 exclusion phecode
255.2 Adrenal hypofunction Endocrine/metabolic 1.15 0.981 – 1.34 0.0859 194 1232 exclusion phecode
255.21 Glucocorticoid deficiency Endocrine/metabolic 1.13 0.967 – 1.33 0.12 185 1168 exclusion phecode
256 Ovarian dysfunction Endocrine/metabolic 0.909 0.814 – 1.01 0.0857 387 1873 exclusion phecode
256.4 Polycystic ovaries Endocrine/metabolic 0.944 0.828 – 1.08 0.388 264 1315 exclusion phecode
257 Testicular dysfunction Endocrine/metabolic 0.963 0.867 – 1.07 0.478 460 1943 exclusion phecode
257.1 Testicular hypofunction Endocrine/metabolic 0.973 0.875 – 1.08 0.613 447 1876 exclusion phecode
258 Iatrogenic endocrine disorders Endocrine/metabolic 1.12 0.772 – 1.64 0.544 34 227 exclusion phecode
258.1 Postablative ovarian failure Endocrine/metabolic 1.1 0.772 – 1.57 0.599 38 180 exclusion phecode
259 Other endocrine disorders Endocrine/metabolic 1.09 0.972 – 1.21 0.144 388 2138 exclusion phecode
260 Protein-calorie malnutrition Endocrine/metabolic 1.07 0.999 – 1.16 0.053 888 4113 exclusion phecode
260.1 Cachexia Endocrine/metabolic 1.19 0.942 – 1.5 0.144 85 434 exclusion phecode
260.2 severe protein-calorie malnutrition Endocrine/metabolic 1.05 0.956 – 1.16 0.298 504 2601 exclusion phecode
260.22 Nutritional marasmus Endocrine/metabolic 1.04 0.89 – 1.21 0.633 197 956 exclusion phecode
260.3 Adult failure to thrive Endocrine/metabolic 1.07 0.926 – 1.25 0.343 215 1006 exclusion phecode
260.6 Anorexia Endocrine/metabolic 0.946 0.834 – 1.07 0.385 299 1455 exclusion phecode
260.7 Polyphagia Endocrine/metabolic 1.08 0.704 – 1.64 0.737 28 186 exclusion phecode
261 Vitamin deficiency Endocrine/metabolic 1 0.955 – 1.05 0.988 3082 5515 exclusion phecode
261.1 Vitamin A deficiency Endocrine/metabolic 1.26 0.849 – 1.87 0.252 33 147 exclusion phecode
261.2 Vitamin B-complex deficiencies Endocrine/metabolic 1.08 0.956 – 1.21 0.224 345 1474 exclusion phecode
261.4 Vitamin D deficiency Endocrine/metabolic 1 0.955 – 1.05 0.989 2923 5517 exclusion phecode
261.41 Rickets or osteomalacia Endocrine/metabolic 0.86 0.477 – 1.55 0.617 18 76 exclusion phecode
262 Mineral deficiency NEC Endocrine/metabolic 1.05 0.96 – 1.16 0.264 583 2068 exclusion phecode
263 Other nutritional deficiency Endocrine/metabolic 1.05 0.959 – 1.14 0.317 629 2700 exclusion phecode
264 Lack of normal physiological development Endocrine/metabolic 1.14 0.89 – 1.47 0.297 87 362 exclusion phecode
264.2 Failure to thrive (childhood) Endocrine/metabolic 1.04 0.761 – 1.42 0.806 40 188 exclusion phecode
264.9
Lack of normal physiological development
Lack of normal physiological development, unspecified
 Endocrine/metabolic 1.21 0.762 – 1.92 0.422 31 117 exclusion phecode
269 Proteinuria Endocrine/metabolic 1.1 1.03 – 1.18 0.00751 1040 3071 exclusion phecode
270
Disorders of protein plasma/amino-acid
Disorders of protein plasma/amino-acid transport and metabolism
 Endocrine/metabolic 0.957 0.858 – 1.07 0.435 393 1961 exclusion phecode
270.1 Disturbances of amino-acid transport Endocrine/metabolic 0.888 0.637 – 1.24 0.485 42 308 exclusion phecode
270.11
Disturbances of sulphur-bearing amino-acid
Disturbances of sulphur-bearing amino-acid metabolism
 Endocrine/metabolic 0.862 0.591 – 1.26 0.439 31 259 exclusion phecode
270.2 Disorders of amino-acid metabolism Endocrine/metabolic 0.761 0.552 – 1.05 0.0956 47 207 exclusion phecode
270.3 Disorders of plasma protein metabolism Endocrine/metabolic 0.994 0.879 – 1.12 0.922 321 1539 exclusion phecode
270.32 Paraproteinemia Endocrine/metabolic 1.01 0.854 – 1.2 0.897 173 844 exclusion phecode
270.33 Amyloidosis Endocrine/metabolic 1.7 1.08 – 2.68 0.0207 23 142 exclusion phecode
270.34 Alpha-1-antitrypsin deficiency Endocrine/metabolic 0.833 0.56 – 1.24 0.365 28 154 exclusion phecode
270.38
Other specified disorders of plasma protein
Other specified disorders of plasma protein metabolism
 Endocrine/metabolic 1.01 0.836 – 1.21 0.941 132 574 exclusion phecode
271
Disorders of carbohydrate transport and
Disorders of carbohydrate transport and metabolism
 Endocrine/metabolic 0.904 0.846 – 0.966 0.00274 1033 5694 exclusion phecode
271.3
Intestinal disaccharidase deficiencies and
Intestinal disaccharidase deficiencies and disaccharide malabsorption
 Endocrine/metabolic 0.91 0.851 – 0.973 0.0058 1004 5551 exclusion phecode
271.9
Other disorders of carbohydrate transport and
Other disorders of carbohydrate transport and metabolism
 Endocrine/metabolic 0.773 0.567 – 1.05 0.102 39 229 exclusion phecode
272 Disorders of lipoid metabolism Endocrine/metabolic 1.38 1.31 – 1.45 6.28e-35 5679 3855 exclusion phecode
272.1 Hyperlipidemia Endocrine/metabolic 1.38 1.31 – 1.45 3.97e-35 5668 3853 exclusion phecode
272.11 Hypercholesterolemia Endocrine/metabolic 1.59 1.48 – 1.71 4.69e-35 2064 3096 exclusion phecode
272.12 Hyperglyceridemia Endocrine/metabolic 1.31 1.19 – 1.44 2.63e-08 712 1661 exclusion phecode
272.13 Mixed hyperlipidemia Endocrine/metabolic 1.54 1.42 – 1.66 5.96e-29 1744 2534 exclusion phecode
272.9 Unspecified disorder of lipoid metabolism Endocrine/metabolic 1.38 1.12 – 1.71 0.00305 125 427 exclusion phecode
274 Gout and other crystal arthropathies Endocrine/metabolic 1.03 0.959 – 1.1 0.459 1021 4780 exclusion phecode
274.1 Gout Endocrine/metabolic 1.03 0.961 – 1.1 0.408 977 4652 exclusion phecode
274.11 Gouty arthropathy Endocrine/metabolic 0.987 0.898 – 1.08 0.78 565 2505 exclusion phecode
274.2 Crystal arthropathies Endocrine/metabolic 0.974 0.762 – 1.25 0.835 82 410 exclusion phecode
274.21 Chondrocalcinosis Endocrine/metabolic 0.923 0.719 – 1.18 0.529 76 380 exclusion phecode
275 Disorders of mineral metabolism Endocrine/metabolic 1.04 0.984 – 1.1 0.168 1628 7003 exclusion phecode
275.1 Disorders of iron metabolism Hematopoietic 0.907 0.707 – 1.16 0.445 84 443 exclusion phecode
275.11 Hereditary hemochromatosis Hematopoietic 0.845 0.585 – 1.22 0.37 34 222 exclusion phecode
275.2 Disorders of copper metabolism Endocrine/metabolic 0.93 0.616 – 1.4 0.73 30 137 exclusion phecode
275.3 Disorders of magnesium metabolism Endocrine/metabolic 1.12 1.01 – 1.24 0.0301 487 2346 exclusion phecode
275.5 Disorders of calcium/phosphorus metabolism Endocrine/metabolic 1.02 0.962 – 1.09 0.472 1242 5996 exclusion phecode
275.51 Hypocalcemia Endocrine/metabolic 1.02 0.9 – 1.15 0.779 305 1668 exclusion phecode
275.53 Disorders of phosphorus metabolism Endocrine/metabolic 1.03 0.942 – 1.13 0.507 580 2623 exclusion phecode
275.6 Hypercalcemia Endocrine/metabolic 1.01 0.922 – 1.1 0.869 585 3003 exclusion phecode
276
Disorders of fluid, electrolyte, and acid-base
Disorders of fluid, electrolyte, and acid-base balance
 Endocrine/metabolic 1.04 0.994 – 1.08 0.0933 3458 6053 exclusion phecode
276.1 Electrolyte imbalance Endocrine/metabolic 1.04 0.996 – 1.1 0.0721 2564 5636 exclusion phecode
276.11 Hyperosmolality and/or hypernatremia Endocrine/metabolic 0.988 0.864 – 1.13 0.863 262 1017 exclusion phecode
276.12 Hyposmolality and/or hyponatremia Endocrine/metabolic 1.05 0.984 – 1.13 0.137 1050 3848 exclusion phecode
276.13 Hyperpotassemia Endocrine/metabolic 1.07 1 – 1.13 0.0385 1407 4299 exclusion phecode
276.14 Hypopotassemia Endocrine/metabolic 1.02 0.948 – 1.1 0.573 865 3516 exclusion phecode
276.4 Acid-base balance disorder Endocrine/metabolic 1.09 1.01 – 1.17 0.0178 999 3475 exclusion phecode
276.41 Acidosis Endocrine/metabolic 1.07 0.994 – 1.16 0.0726 871 3067 exclusion phecode
276.42 Alkalosis Endocrine/metabolic 1.17 1.01 – 1.35 0.0399 222 885 exclusion phecode
276.5 Hypovolemia Endocrine/metabolic 1.06 1.01 – 1.12 0.0271 1733 5592 exclusion phecode
276.6 Fluid overload Endocrine/metabolic 1.01 0.928 – 1.09 0.883 777 2360 exclusion phecode
276.8 Polydipsia Endocrine/metabolic 1.07 0.78 – 1.47 0.672 48 243 exclusion phecode
277 Other disorders of metabolism Endocrine/metabolic 1.03 0.973 – 1.08 0.331 1698 6591 exclusion phecode
277.2
Other disorders of purine and pyrimidine
Other disorders of purine and pyrimidine metabolism
 Endocrine/metabolic 1.02 0.875 – 1.2 0.761 206 1102 exclusion phecode
277.4 Disorders of bilirubin excretion Endocrine/metabolic 0.954 0.839 – 1.08 0.468 301 1459 exclusion phecode
277.5 Other disorders of lipoid metabolism Endocrine/metabolic 0.961 0.866 – 1.07 0.458 434 2099 exclusion phecode
277.51 Lipoprotein disorders Endocrine/metabolic 0.962 0.858 – 1.08 0.512 364 1753 exclusion phecode
277.7 Dysmetabolic syndrome X Endocrine/metabolic 1.05 0.946 – 1.16 0.379 478 2058 exclusion phecode
278 Overweight, obesity and other hyperalimentation Endocrine/metabolic 0.982 0.943 – 1.02 0.396 5231 4434 exclusion phecode
278.1 Obesity Endocrine/metabolic 0.973 0.933 – 1.02 0.207 4572 4431 exclusion phecode
278.11 Morbid obesity Endocrine/metabolic 0.971 0.923 – 1.02 0.256 2451 4374 exclusion phecode
278.3 Localized adiposity Endocrine/metabolic 0.948 0.782 – 1.15 0.587 130 546 exclusion phecode
278.4 Abnormal weight gain Endocrine/metabolic 0.996 0.921 – 1.08 0.917 844 2845 exclusion phecode
279 Disorders involving the immune mechanism Endocrine/metabolic 1.04 0.981 – 1.11 0.173 1247 5013 exclusion phecode
279.1 Immunity deficiency Endocrine/metabolic 1.11 1 – 1.22 0.0459 527 2081 exclusion phecode
279.11 Deficiency of humoral immunity Endocrine/metabolic 1.08 0.884 – 1.31 0.465 128 636 exclusion phecode
279.2 Autoimmune disease NEC Endocrine/metabolic 1.09 0.959 – 1.25 0.181 270 1441 exclusion phecode
279.7 Other immunological findings Endocrine/metabolic 1.02 0.971 – 1.07 0.413 2058 6405 exclusion phecode
279.8
Other specified disorders involving the immune
Other specified disorders involving the immune mechanism
 Endocrine/metabolic 1.1 0.954 – 1.27 0.186 231 1146 exclusion phecode
280 Iron deficiency anemias Hematopoietic 1.09 1.04 – 1.16 0.000972 1997 4825 exclusion phecode
280.1
Iron deficiency anemias, unspecified or not due
Iron deficiency anemias, unspecified or not due to blood loss
 Hematopoietic 1.09 1.03 – 1.15 0.00177 1938 4789 exclusion phecode
280.2
Iron deficiency anemia secondary to blood loss
Iron deficiency anemia secondary to blood loss (chronic)
 Hematopoietic 1.06 0.974 – 1.15 0.184 781 2762 exclusion phecode
281 Other deficiency anemia Hematopoietic 1.09 0.947 – 1.26 0.224 240 834 exclusion phecode
281.1 Megaloblastic anemia Hematopoietic 1.11 0.9 – 1.37 0.325 108 422 exclusion phecode
281.11 Pernicious anemia Hematopoietic 1.06 0.76 – 1.48 0.734 51 199 exclusion phecode
281.12 Other vitamin B12 deficiency anemia Hematopoietic 1.16 0.9 – 1.49 0.251 73 310 exclusion phecode
281.9 Deficiency anemias Hematopoietic 1.11 0.919 – 1.34 0.275 149 451 exclusion phecode
282 Hereditary hemolytic anemias Hematopoietic 0.944 0.775 – 1.15 0.571 134 557 exclusion phecode
282.8 Other hemoglobinopathies Hematopoietic 1.01 0.798 – 1.29 0.905 91 414 exclusion phecode
282.9 Other hereditary hemolytic anemias Hematopoietic 1.09 0.856 – 1.39 0.484 86 342 exclusion phecode
283 Acquired hemolytic anemias Hematopoietic 0.839 0.634 – 1.11 0.22 77 286 exclusion phecode
283.1 Autoimmune hemolytic anemias Hematopoietic 0.628 0.411 – 0.96 0.0318 30 122 exclusion phecode
284 Aplastic anemia Hematopoietic 1.16 1.02 – 1.33 0.0286 314 1151 exclusion phecode
284.1 Pancytopenia Hematopoietic 1.18 1.02 – 1.37 0.022 272 1006 exclusion phecode
285 Other anemias Hematopoietic 1.08 1.03 – 1.12 0.000671 4012 5235 exclusion phecode
285.1 Acute posthemorrhagic anemia Hematopoietic 1.13 1.06 – 1.21 0.00034 1210 4141 exclusion phecode
285.2 Anemia of chronic disease Hematopoietic 1.1 1.02 – 1.19 0.012 957 3176 exclusion phecode
285.21 Anemia in chronic kidney disease Hematopoietic 1.06 0.961 – 1.17 0.241 589 1688 exclusion phecode
285.22 Anemia in neoplastic disease Hematopoietic 1.05 0.886 – 1.24 0.594 179 955 exclusion phecode
286 Coagulation defects Hematopoietic 1.08 1.02 – 1.14 0.0132 1401 5809 exclusion phecode
286.1 Congenital coagulation defects Hematopoietic 0.884 0.685 – 1.14 0.345 71 465 exclusion phecode
286.11 Von willebrand's disease Hematopoietic 0.79 0.496 – 1.26 0.32 19 157 exclusion phecode
286.12
Congenital deficiency of other clotting factors
Congenital deficiency of other clotting factors (including factor VII)
 Hematopoietic 0.908 0.646 – 1.28 0.58 36 250 exclusion phecode
286.2
Encounter for long-term (current) use of
Encounter for long-term (current) use of anticoagulants
 Hematopoietic 1.1 1.03 – 1.17 0.00333 1406 4555 exclusion phecode
286.3
Coagulation defects complicating pregnancy or
Coagulation defects complicating pregnancy or postpartum
 Hematopoietic 0.749 0.514 – 1.09 0.132 33 216 exclusion phecode
286.4 Acquired coagulation factor deficiency Hematopoietic 0.945 0.769 – 1.16 0.593 118 492 exclusion phecode
286.5
Hemorrhagic disorder due to intrinsic
Hemorrhagic disorder due to intrinsic circulating anticoagulants
 Hematopoietic 1.17 0.882 – 1.55 0.277 61 269 exclusion phecode
286.6 Defibrination syndrome Hematopoietic 1.07 0.995 – 1.15 0.0692 892 4540 exclusion phecode
286.7 Other and unspecified coagulation defects Hematopoietic 1.07 1 – 1.15 0.0404 1077 5172 exclusion phecode
286.8 Hypercoagulable state Hematopoietic 0.998 0.871 – 1.14 0.975 244 1533 exclusion phecode
286.81 Primary hypercoagulable state Hematopoietic 0.977 0.851 – 1.12 0.738 234 1475 exclusion phecode
286.9 Abnormal coagulation profile Hematopoietic 1.08 0.979 – 1.19 0.125 557 2114 exclusion phecode
287 Purpura and other hemorrhagic conditions Hematopoietic 1.13 1.06 – 1.2 0.000145 1326 5057 exclusion phecode
287.1 Spontaneous ecchymoses Hematopoietic 1.22 0.954 – 1.56 0.114 82 401 exclusion phecode
287.3 Thrombocytopenia Hematopoietic 1.14 1.07 – 1.22 7.72e-05 1203 4696 exclusion phecode
287.31 Primary thrombocytopenia Hematopoietic 1.21 1.03 – 1.42 0.022 189 1070 exclusion phecode
287.32 Secondary thrombocytopenia Hematopoietic 1.14 0.983 – 1.33 0.0821 208 1015 exclusion phecode
287.4 Qualitative platelet defects Hematopoietic 1.18 0.815 – 1.7 0.386 39 205 exclusion phecode
288 Diseases of white blood cells Hematopoietic 1.01 0.962 – 1.07 0.6 1829 6382 exclusion phecode
288.1 Decreased white blood cell count Hematopoietic 1.05 0.954 – 1.15 0.336 572 2808 exclusion phecode
288.11 Neutropenia Hematopoietic 1.03 0.921 – 1.16 0.58 378 1937 exclusion phecode
288.2 Elevated white blood cell count Hematopoietic 1.01 0.956 – 1.07 0.701 1606 6166 exclusion phecode
288.3 Eosinophilia Hematopoietic 1.21 0.91 – 1.6 0.191 48 359 exclusion phecode
289 Other diseases of blood and blood-forming organs Hematopoietic 1.02 0.938 – 1.11 0.663 713 3255 exclusion phecode
289.3
Personal history of diseases of blood and
Personal history of diseases of blood and blood-forming organs
 Hematopoietic 1.08 0.959 – 1.22 0.2 358 1665 exclusion phecode
289.4 Lymphadenitis Hematopoietic 1.02 0.954 – 1.09 0.58 1100 6068 exclusion phecode
289.5 Diseases of spleen Hematopoietic 1.02 0.863 – 1.22 0.779 168 754 exclusion phecode
289.8 Polycythemia, secondary Hematopoietic 0.983 0.811 – 1.19 0.864 126 546 exclusion phecode
289.9 Abnormality of red blood cells Hematopoietic 0.968 0.825 – 1.14 0.688 181 808 exclusion phecode
290
Delirium dementia and amnestic and other
Delirium dementia and amnestic and other cognitive disorders
 Mental Disorders 1.04 0.943 – 1.14 0.461 554 2261 exclusion phecode
290.1 Dementias Mental Disorders 0.998 0.862 – 1.15 0.976 222 1011 exclusion phecode
290.11 Alzheimer's disease Mental Disorders 1.24 0.947 – 1.63 0.117 63 297 exclusion phecode
290.12 Dementia with cerebral degenerations Mental Disorders 1.03 0.736 – 1.43 0.879 46 162 exclusion phecode
290.13 Senile dementia Mental Disorders 0.886 0.738 – 1.06 0.193 145 620 exclusion phecode
290.16 Vascular dementia Mental Disorders 1.08 0.747 – 1.57 0.678 42 157 exclusion phecode
290.2 Delirium due to conditions classified elsewhere Mental Disorders 1.04 0.927 – 1.18 0.48 338 1417 exclusion phecode
290.3
Other persistent mental disorders due to
Other persistent mental disorders due to conditions classified elsewhere
 Mental Disorders 1.03 0.915 – 1.16 0.619 340 1787 exclusion phecode
291
Other specified nonpsychotic and/or transient
Other specified nonpsychotic and/or transient mental disorders
 Mental Disorders 1.02 0.948 – 1.09 0.658 991 4769 exclusion phecode
291.1
Transient mental disorders due to conditions
Transient mental disorders due to conditions classified elsewhere
 Mental Disorders 1.01 0.769 – 1.32 0.958 64 389 exclusion phecode
291.4
Specific nonpsychotic mental disorders due to
Specific nonpsychotic mental disorders due to brain damage
 Mental Disorders 1.04 0.885 – 1.23 0.607 173 924 exclusion phecode
291.8 Alteration of consciousness Mental Disorders 1.02 0.941 – 1.1 0.68 808 3871 exclusion phecode
292 Neurological disorders Mental Disorders 0.994 0.945 – 1.05 0.831 2012 6897 exclusion phecode
292.1 Aphasia/speech disturbance Mental Disorders 0.971 0.891 – 1.06 0.508 596 3623 exclusion phecode
292.11 Aphasia Mental Disorders 0.964 0.833 – 1.12 0.626 215 1193 exclusion phecode
292.12 Symbolic dysfunction Mental Disorders 0.942 0.712 – 1.25 0.673 50 354 exclusion phecode
292.2 Mild cognitive impairment Mental Disorders 0.996 0.848 – 1.17 0.966 188 757 exclusion phecode
292.3 Memory loss Mental Disorders 0.995 0.918 – 1.08 0.908 719 3457 exclusion phecode
292.4 Altered mental status Mental Disorders 0.997 0.932 – 1.07 0.942 1049 4350 exclusion phecode
292.5 Transient alteration of awareness Mental Disorders 0.999 0.851 – 1.17 0.992 184 887 exclusion phecode
292.6 Hallucinations Mental Disorders 0.84 0.676 – 1.04 0.114 93 401 exclusion phecode
293 Symptoms involving head and neck Mental Disorders 0.93 0.776 – 1.11 0.43 135 861 exclusion phecode
293.1
Swelling, mass, or lump in head and neck
Swelling, mass, or lump in head and neck [Space-occupying lesion, intracranial NOS]
 Mental Disorders 1.01 0.944 – 1.07 0.845 1093 7651 exclusion phecode
295 Schizophrenia and other psychotic disorders Mental Disorders 0.95 0.843 – 1.07 0.398 371 1210 exclusion phecode
295.1 Schizophrenia Mental Disorders 1.13 0.791 – 1.62 0.499 38 211 exclusion phecode
295.2 Paranoid disorders Mental Disorders 0.932 0.655 – 1.33 0.696 46 155 exclusion phecode
295.3 Psychosis Mental Disorders 0.959 0.841 – 1.09 0.527 320 1037 exclusion phecode
296 Mood disorders Mental Disorders 0.981 0.933 – 1.03 0.437 4100 2877 exclusion phecode
296.1 Bipolar Mental Disorders 1.03 0.921 – 1.16 0.589 384 1539 exclusion phecode
296.2 Depression Mental Disorders 0.983 0.935 – 1.03 0.494 3956 2877 exclusion phecode
296.22 Major depressive disorder Mental Disorders 0.976 0.927 – 1.03 0.345 3663 2874 exclusion phecode
297 Suicidal ideation or attempt Mental Disorders 0.962 0.852 – 1.09 0.526 361 1257 exclusion phecode
297.1 Suicidal ideation Mental Disorders 1.01 0.879 – 1.15 0.921 289 1042 exclusion phecode
297.2 Suicide or self-inflicted injury Mental Disorders 0.998 0.801 – 1.24 0.985 104 364 exclusion phecode
300 Anxiety disorders Mental Disorders 0.976 0.929 – 1.03 0.348 4064 2877 exclusion phecode
300.1 Anxiety disorder Mental Disorders 0.978 0.93 – 1.03 0.39 3817 2880 exclusion phecode
300.11 Generalized anxiety disorder Mental Disorders 0.948 0.89 – 1.01 0.0947 1751 2820 exclusion phecode
300.12 Agorophobia, social phobia, and panic disorder Mental Disorders 0.997 0.896 – 1.11 0.962 457 1569 exclusion phecode
300.13 Phobia Mental Disorders 0.907 0.8 – 1.03 0.124 344 1373 exclusion phecode
300.3 Obsessive-compulsive disorders Mental Disorders 0.852 0.695 – 1.05 0.125 110 509 exclusion phecode
300.4 Dysthymic disorder Mental Disorders 0.935 0.862 – 1.01 0.1 849 2320 exclusion phecode
300.8 Acute reaction to stress Mental Disorders 0.929 0.795 – 1.08 0.35 198 767 exclusion phecode
300.9 Posttraumatic stress disorder Mental Disorders 0.985 0.848 – 1.15 0.847 224 1086 exclusion phecode
301 Personality disorders Mental Disorders 1 0.836 – 1.2 0.999 153 656 exclusion phecode
301.2 Antisocial/borderline personality disorder Mental Disorders 1.03 0.8 – 1.31 0.84 77 352 exclusion phecode
302 Sexual and gender identity disorders Mental Disorders 0.957 0.89 – 1.03 0.235 1300 2056 exclusion phecode
302.1 Decreased libido Mental Disorders 0.82 0.695 – 0.967 0.0184 183 781 exclusion phecode
303 Psychogenic and somatoform disorders Mental Disorders 0.956 0.903 – 1.01 0.116 2417 2780 exclusion phecode
303.1 Dissociative disorder Mental Disorders 0.944 0.685 – 1.3 0.725 42 246 exclusion phecode
303.3 Psychogenic disorder Mental Disorders 0.951 0.898 – 1.01 0.0878 2332 2753 exclusion phecode
303.31
Gastrointestinal malfunction arising from
Gastrointestinal malfunction arising from mental factors
 Mental Disorders 0.875 0.734 – 1.04 0.135 152 713 exclusion phecode
303.4 Somatoform disorder Mental Disorders 1.01 0.89 – 1.14 0.917 308 1497 exclusion phecode
304 Adjustment reaction Mental Disorders 0.932 0.87 – 0.997 0.0403 1351 2839 exclusion phecode
305.2 Eating disorder Mental Disorders 0.92 0.818 – 1.04 0.168 354 1266 exclusion phecode
306 Other mental disorder Mental Disorders 0.961 0.876 – 1.05 0.397 632 1995 exclusion phecode
306.1 Mental disorders durring/after pregnancy Mental Disorders 1.14 0.957 – 1.37 0.139 186 521 exclusion phecode
306.9 Tension headache Mental Disorders 0.908 0.787 – 1.05 0.189 254 1119 exclusion phecode
312 Conduct disorders Mental Disorders 0.906 0.722 – 1.14 0.391 98 469 exclusion phecode
312.3 Impulse control disorder Mental Disorders 0.806 0.541 – 1.2 0.288 26 172 exclusion phecode
313 Pervasive developmental disorders Mental Disorders 0.959 0.863 – 1.06 0.431 437 2805 exclusion phecode
313.1 Attention deficit hyperactivity disorder Mental Disorders 0.958 0.856 – 1.07 0.452 378 2488 exclusion phecode
313.2 Tics and stuttering Mental Disorders 0.668 0.423 – 1.05 0.0836 26 122 exclusion phecode
313.3 Autism Mental Disorders 1.11 0.683 – 1.8 0.68 23 106 exclusion phecode
315 Develomental delays and disorders Mental Disorders 1.08 0.943 – 1.23 0.276 269 1348 exclusion phecode
315.1 Learning disorder Mental Disorders 0.869 0.603 – 1.25 0.454 37 171 exclusion phecode
315.2 Speech and language disorder Mental Disorders 1.06 0.832 – 1.34 0.649 82 448 exclusion phecode
316 Substance addiction and disorders Mental Disorders 1.04 0.974 – 1.11 0.232 1043 5713 exclusion phecode
316.1 Polyneuropathy due to drugs Mental Disorders 1.09 0.906 – 1.3 0.372 141 1014 exclusion phecode
317 Alcohol-related disorders Mental Disorders 1.06 0.978 – 1.14 0.164 767 4157 exclusion phecode
317.1 Alcoholism Mental Disorders 1.04 0.959 – 1.14 0.328 638 3533 exclusion phecode
317.11 Alcoholic liver damage Mental Disorders 1.03 0.87 – 1.22 0.738 172 772 exclusion phecode
318 Tobacco use disorder Mental Disorders 1.04 0.992 – 1.09 0.0999 2393 6376 exclusion phecode
320 Meningitis Neurological 1.13 0.921 – 1.38 0.245 103 723 exclusion phecode
323 Encephalitis Neurological 0.774 0.588 – 1.02 0.0678 57 377 exclusion phecode
323.8 Encephalitis, non-infectious Neurological 0.791 0.597 – 1.05 0.105 51 307 exclusion phecode
324 Other CNS infection and poliomyelitis Neurological 1.02 0.81 – 1.3 0.842 73 594 exclusion phecode
325
Phlebitis and thrombophlebitis of intracranial
Phlebitis and thrombophlebitis of intracranial venous sinuses
 Neurological 0.858 0.527 – 1.4 0.539 16 120 exclusion phecode
327 Sleep disorders Neurological 0.983 0.943 – 1.02 0.402 4707 4911 exclusion phecode
327.1 Hypersomnia Neurological 0.965 0.894 – 1.04 0.359 836 3183 exclusion phecode
327.3 Sleep apnea Neurological 0.988 0.945 – 1.03 0.615 3462 4848 exclusion phecode
327.31 Central/nonobstroctive sleep apnea Neurological 1.04 0.901 – 1.21 0.567 222 927 exclusion phecode
327.32 Obstructive sleep apnea Neurological 0.973 0.929 – 1.02 0.253 3078 4752 exclusion phecode
327.4 Insomnia Neurological 0.956 0.908 – 1.01 0.0959 2090 4805 exclusion phecode
327.41 Organic or persistent insomnia Neurological 0.915 0.829 – 1.01 0.0732 529 2041 exclusion phecode
327.5 Parasomnia Neurological 0.968 0.844 – 1.11 0.643 265 1049 exclusion phecode
327.6 Circadian rhythm sleep disorder Neurological 0.93 0.757 – 1.14 0.485 127 547 exclusion phecode
327.7 Sleep related movement disorders Neurological 0.901 0.827 – 0.982 0.0181 644 2781 exclusion phecode
327.71 Restless legs syndrome Neurological 0.904 0.825 – 0.992 0.0329 550 2452 exclusion phecode
327.72 Sleep related leg cramps Neurological 1.06 0.719 – 1.56 0.767 38 143 exclusion phecode
331 Other cerebral degenerations Neurological 1.06 0.921 – 1.23 0.407 244 1390 exclusion phecode
331.1 Hydrocephalus Neurological 1.07 0.795 – 1.43 0.672 45 465 exclusion phecode
331.9 Cerebral degeneration, unspecified Neurological 0.999 0.847 – 1.18 0.994 196 855 exclusion phecode
332 Parkinson's disease Neurological 0.831 0.692 – 0.998 0.0473 137 829 exclusion phecode
333
Extrapyramidal disease and abnormal movement
Extrapyramidal disease and abnormal movement disorders
 Neurological 0.909 0.849 – 0.973 0.00574 989 5040 exclusion phecode
333.1 Essential tremor Neurological 0.919 0.811 – 1.04 0.188 276 1451 exclusion phecode
333.2 Myoclonus Neurological 1.11 0.852 – 1.45 0.436 69 299 exclusion phecode
333.4 Torsion dystonia Neurological 0.919 0.735 – 1.15 0.455 96 615 exclusion phecode
333.8 Other degenerative diseases of the basal ganglia Neurological 1.09 0.77 – 1.55 0.618 44 201 exclusion phecode
334 Degenerative disease of the spinal cord Neurological 0.863 0.759 – 0.98 0.0235 260 1858 exclusion phecode
334.1 Spinocerebellar disease Neurological 0.833 0.555 – 1.25 0.377 34 161 exclusion phecode
334.2 Anterior horn cell disease Neurological 0.641 0.435 – 0.943 0.0239 26 223 exclusion phecode
334.21 Amyotrophic Lateral Sclerosis Neurological 0.763 0.493 – 1.18 0.223 20 135 exclusion phecode
335 Multiple sclerosis Neurological 0.954 0.774 – 1.17 0.657 98 674 exclusion phecode
337 Disorders of the autonomic nervous system Neurological 1.03 0.918 – 1.15 0.643 358 1845 exclusion phecode
337.1 Peripheral autonomic neuropathy Neurological 1.01 0.873 – 1.16 0.942 248 1126 exclusion phecode
338 Pain Neurological 0.966 0.927 – 1.01 0.105 5169 4494 exclusion phecode
338.1 Acute pain Neurological 0.972 0.929 – 1.02 0.219 3716 4460 exclusion phecode
338.2 Chronic pain Neurological 0.96 0.917 – 1.01 0.0867 3366 4466 exclusion phecode
339 Other headache syndromes Neurological 0.974 0.929 – 1.02 0.27 2691 6364 exclusion phecode
340 Migraine Neurological 0.946 0.895 – 0.999 0.046 1799 5505 exclusion phecode
340.1 Migrain with aura Neurological 0.965 0.9 – 1.03 0.311 1019 4148 exclusion phecode
341
Other demyelinating diseases of central nervous
Other demyelinating diseases of central nervous system
 Neurological 1.04 0.744 – 1.45 0.827 45 254 exclusion phecode
342 Hemiplegia Neurological 0.951 0.808 – 1.12 0.545 177 875 exclusion phecode
343 Infantile cerebral palsy Neurological 1.15 0.688 – 1.93 0.589 19 136 exclusion phecode
344 Other paralytic syndromes Neurological 1.03 0.888 – 1.2 0.684 200 1132 exclusion phecode
345 Epilepsy, recurrent seizures, convulsions Neurological 0.975 0.899 – 1.06 0.535 669 4596 exclusion phecode
345.1 Epilepsy Neurological 0.963 0.834 – 1.11 0.613 209 1332 exclusion phecode
345.11 Generalized convulsive epilepsy Neurological 1.03 0.793 – 1.35 0.808 60 399 exclusion phecode
345.12 Partial epilepsy Neurological 0.946 0.796 – 1.12 0.528 145 946 exclusion phecode
345.3 Convulsions Neurological 0.971 0.893 – 1.05 0.482 637 4339 exclusion phecode
346
Abnormal findings on study of brain and/or
Abnormal findings on study of brain and/or nervous system
 Neurological 0.787 0.594 – 1.04 0.0952 54 332 exclusion phecode
346.1
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of skull and head
 Neurological 0.991 0.9 – 1.09 0.857 467 2767 exclusion phecode
346.2
Nonspecific abnormal results of function study
Nonspecific abnormal results of function study of brain and central nervous system
 Neurological 0.818 0.57 – 1.17 0.275 38 210 exclusion phecode
346.3
Nonspecific abnormal findings in cerebrospinal
Nonspecific abnormal findings in cerebrospinal fluid
 Neurological 0.818 0.552 – 1.21 0.317 29 186 exclusion phecode
347 Cataplexy and narcolepsy Neurological 1.17 0.779 – 1.76 0.446 25 213 exclusion phecode
348 Other conditions of brain Neurological 0.961 0.876 – 1.05 0.392 530 3263 exclusion phecode
348.2 Cerebral edema and compression of brain Neurological 0.932 0.8 – 1.09 0.367 169 1532 exclusion phecode
348.4 Cerebral cysts Neurological 0.746 0.559 – 0.995 0.0463 49 416 exclusion phecode
348.7 Coma Neurological 1.24 0.96 – 1.61 0.0997 79 449 exclusion phecode
348.8 Encephalopathy, not elsewhere classified Neurological 1.02 0.91 – 1.15 0.704 349 1621 exclusion phecode
348.9 Other conditions of brain, NOS Neurological 0.982 0.902 – 1.07 0.666 610 4145 exclusion phecode
349
Other and unspecified disorders of the nervous
Other and unspecified disorders of the nervous system
 Neurological 0.935 0.821 – 1.06 0.305 275 1634 exclusion phecode
350 Abnormal movement Neurological 0.982 0.936 – 1.03 0.465 2326 6954 exclusion phecode
350.1 Abnormal involuntary movements Neurological 0.977 0.917 – 1.04 0.473 1167 5629 exclusion phecode
350.2 Abnormality of gait Neurological 0.958 0.904 – 1.02 0.152 1460 5510 exclusion phecode
350.3 Lack of coordination Neurological 1.03 0.922 – 1.16 0.583 373 1959 exclusion phecode
350.5 Abnormal reflex Neurological 0.928 0.707 – 1.22 0.591 66 360 exclusion phecode
350.6 Disturbances of sensation of smell and taste Neurological 0.995 0.837 – 1.18 0.958 134 1038 exclusion phecode
351 Other peripheral nerve disorders Neurological 0.922 0.879 – 0.966 0.000757 2515 6009 exclusion phecode
352 Disorders of other cranial nerves Neurological 0.937 0.837 – 1.05 0.261 346 2885 exclusion phecode
352.1 Trigeminal nerve disorders [CN5] Neurological 0.865 0.717 – 1.04 0.132 131 850 exclusion phecode
352.2 Facial nerve disorders [CN7] Neurological 0.939 0.803 – 1.1 0.435 181 1334 exclusion phecode
353 Nerve root and plexus disorders Neurological 0.946 0.89 – 1 0.0686 1337 5759 exclusion phecode
353.1 Nerve plexus lesions Neurological 0.895 0.712 – 1.13 0.344 89 686 exclusion phecode
353.2 Nerve root lesions Neurological 0.82 0.589 – 1.14 0.24 37 250 exclusion phecode
355 Complex regional/central pain syndrome Neurological 0.995 0.836 – 1.18 0.955 139 904 exclusion phecode
355.1 Chronic pain syndrome Neurological 0.914 0.805 – 1.04 0.163 291 1467 exclusion phecode
356 Hereditary and idiopathic peripheral neuropathy Neurological 0.983 0.917 – 1.05 0.625 1010 4136 exclusion phecode
357 Inflammatory and toxic neuropathy Neurological 0.998 0.94 – 1.06 0.95 1360 5669 exclusion phecode
358 Myoneural disorders Neurological 0.964 0.867 – 1.07 0.505 387 2283 exclusion phecode
358.1 Myasthenia gravis Neurological 0.836 0.518 – 1.35 0.462 23 197 exclusion phecode
359 Muscular dystrophies and other myopathies Neurological 0.978 0.879 – 1.09 0.675 378 2177 exclusion phecode
359.1 Muscular dystrophies Neurological 0.707 0.392 – 1.27 0.248 13 122 exclusion phecode
359.2 Myopathy Neurological 0.973 0.874 – 1.08 0.61 370 2102 exclusion phecode
360 Disorders of the globe Sense Organs 0.902 0.689 – 1.18 0.453 62 306 exclusion phecode
360.2 Progressive myopia Sense Organs 1.07 0.738 – 1.54 0.732 32 141 exclusion phecode
361 Retinal detachments and defects Sense Organs 0.877 0.775 – 0.993 0.0389 295 1588 exclusion phecode
361.1 Retinal detachment with retinal defect Sense Organs 0.915 0.758 – 1.1 0.354 120 662 exclusion phecode
362 Other retinal disorders Sense Organs 0.96 0.905 – 1.02 0.176 1607 4119 exclusion phecode
362.2
Degeneration of macula and posterior pole of
Degeneration of macula and posterior pole of retina
 Sense Organs 0.969 0.899 – 1.04 0.411 941 2928 exclusion phecode
362.21 Macular degeneration, dry Sense Organs 0.906 0.772 – 1.06 0.229 193 676 exclusion phecode
362.22 Macular degeneration, wet Sense Organs 0.887 0.686 – 1.15 0.358 63 275 exclusion phecode
362.23 Cystoid macular degeneration of retina Sense Organs 1.03 0.878 – 1.21 0.723 180 807 exclusion phecode
362.26 Macular puckering of retina Sense Organs 1.01 0.908 – 1.12 0.89 453 1856 exclusion phecode
362.27 Drusen (degenerative) of retina Sense Organs 0.869 0.754 – 1 0.05 217 972 exclusion phecode
362.29 Macular degeneration (senile) of retina NOS Sense Organs 0.95 0.877 – 1.03 0.204 814 2690 exclusion phecode
362.3 Other nondiabetic retinopathy Sense Organs 0.911 0.827 – 1 0.06 508 1857 exclusion phecode
362.31 Separation of retinal layers Sense Organs 0.874 0.737 – 1.04 0.119 157 925 exclusion phecode
362.4 Retinal vascular changes and abnomalities Sense Organs 0.913 0.812 – 1.03 0.128 320 1339 exclusion phecode
362.6 Peripheral retinal degenerations Sense Organs 0.968 0.829 – 1.13 0.684 170 843 exclusion phecode
362.7 Hereditary retinal dystrophies Sense Organs 1.04 0.832 – 1.31 0.707 88 453 exclusion phecode
362.8 Retinal hemorrhage/ischemia Sense Organs 0.842 0.688 – 1.03 0.0965 103 640 exclusion phecode
362.9 Retinal edema Sense Organs 1.01 0.855 – 1.19 0.928 177 780 exclusion phecode
363
Chorioretinal inflammations, scars, and other
Chorioretinal inflammations, scars, and other disorders of choroid
 Sense Organs 0.861 0.74 – 1 0.0553 190 1001 exclusion phecode
363.3 Chorioretinal scars Sense Organs 0.848 0.711 – 1.01 0.0663 138 698 exclusion phecode
364 Corneal opacity and other disorders of cornea Sense Organs 0.947 0.852 – 1.05 0.308 419 2214 exclusion phecode
364.1 Corneal opacity Sense Organs 0.807 0.68 – 0.959 0.0147 151 858 exclusion phecode
364.2 Corneal edema Sense Organs 0.741 0.543 – 1.01 0.0585 55 284 exclusion phecode
364.4 Corneal degenerations Sense Organs 0.891 0.746 – 1.06 0.201 148 903 exclusion phecode
364.41 Keratoconus Sense Organs 0.859 0.574 – 1.29 0.459 29 178 exclusion phecode
364.5 Corneal dystrophy Sense Organs 1.04 0.888 – 1.21 0.65 188 967 exclusion phecode
364.51 Fuchs' dystrophy Sense Organs 0.964 0.779 – 1.19 0.733 92 560 exclusion phecode
364.9 Cornea replaced by transplant Sense Organs 0.921 0.637 – 1.33 0.664 33 198 exclusion phecode
365 Glaucoma Sense Organs 0.969 0.905 – 1.04 0.38 1000 4103 exclusion phecode
365.1 Open-angle glaucoma Sense Organs 0.988 0.877 – 1.11 0.844 313 1412 exclusion phecode
365.11 Primary open angle glaucoma Sense Organs 1.06 0.908 – 1.25 0.438 177 848 exclusion phecode
365.2 Primary angle-closure glaucoma Sense Organs 1.05 0.858 – 1.29 0.618 107 546 exclusion phecode
366 Cataract Sense Organs 1.02 0.968 – 1.07 0.494 3355 4691 exclusion phecode
366.1 Nonsenile Cataract Sense Organs 1.05 0.836 – 1.32 0.672 88 388 exclusion phecode
366.2 Senile cataract Sense Organs 1 0.948 – 1.06 0.965 2468 4156 exclusion phecode
367
Disorders of refraction and accommodation
Disorders of refraction and accommodation; blindness and low vision
 Sense Organs 0.954 0.915 – 0.996 0.0303 3640 6032 exclusion phecode
367.1 Myopia Sense Organs 0.968 0.919 – 1.02 0.22 2059 5613 exclusion phecode
367.2 Astigmatism Sense Organs 0.946 0.896 – 1 0.0512 1691 5352 exclusion phecode
367.8 Hypermetropia Sense Organs 0.893 0.826 – 0.966 0.00493 784 3254 exclusion phecode
367.9 Blindness and low vision Sense Organs 0.925 0.836 – 1.02 0.129 495 2209 exclusion phecode
368 Visual disturbances Sense Organs 1.01 0.961 – 1.06 0.68 2006 7405 exclusion phecode
368.1 Amblyopia Sense Organs 1.1 0.945 – 1.28 0.221 217 1410 exclusion phecode
368.2 Diplopia and disorders of binocular vision Sense Organs 0.957 0.859 – 1.07 0.426 386 2220 exclusion phecode
368.3 Anisometropia Sense Organs 0.84 0.669 – 1.06 0.135 87 471 exclusion phecode
368.4 Visual field defects Sense Organs 0.962 0.869 – 1.07 0.461 432 2219 exclusion phecode
368.9 Subjective visual disturbances Sense Organs 0.947 0.852 – 1.05 0.316 403 2198 exclusion phecode
368.91 Psychophysical visual disturbances Sense Organs 0.853 0.62 – 1.17 0.33 51 228 exclusion phecode
369 Infection of the eye Sense Organs 0.962 0.903 – 1.02 0.222 1240 4946 exclusion phecode
369.2 Eye infection, viral Sense Organs 1.09 0.922 – 1.29 0.306 178 990 exclusion phecode
369.5 Conjunctivitis, infectious Sense Organs 0.949 0.888 – 1.01 0.127 1082 4509 exclusion phecode
370 Keratitis Sense Organs 0.972 0.884 – 1.07 0.559 517 2507 exclusion phecode
370.1 Corneal ulcer Sense Organs 0.999 0.784 – 1.27 0.995 84 500 exclusion phecode
370.2 Superficial keratitis Sense Organs 0.946 0.815 – 1.1 0.465 213 1020 exclusion phecode
370.3 Keratoconjunctivitis Sense Organs 0.945 0.824 – 1.08 0.423 241 1169 exclusion phecode
370.31 Keratoconjunctivitis sicca Sense Organs 0.99 0.774 – 1.27 0.936 79 304 exclusion phecode
371 Inflammation of the eye Sense Organs 0.944 0.895 – 0.996 0.0362 1779 5798 exclusion phecode
371.1 Uveitis, noninfectious or NOS Sense Organs 0.899 0.777 – 1.04 0.15 210 1129 exclusion phecode
371.2 Conjunctivitis, noninfectious Sense Organs 0.897 0.802 – 1 0.0572 355 1858 exclusion phecode
371.21 Allergic conjunctivitis Sense Organs 0.912 0.809 – 1.03 0.138 302 1566 exclusion phecode
371.3 Inflammation of eyelids Sense Organs 0.937 0.883 – 0.995 0.0334 1399 4897 exclusion phecode
371.33 Noninfectious dermatoses of eyelid Sense Organs 0.889 0.661 – 1.2 0.435 47 247 exclusion phecode
372 Disorders of conjunctiva Sense Organs 1.05 0.944 – 1.18 0.355 420 2128 exclusion phecode
374 Other disorders of eyelids Sense Organs 0.989 0.925 – 1.06 0.737 1102 4337 exclusion phecode
374.1 Ectropion or entropion Sense Organs 0.874 0.736 – 1.04 0.124 142 758 exclusion phecode
374.2 Lagophthalmos Sense Organs 0.955 0.702 – 1.3 0.767 46 369 exclusion phecode
374.3 Ptosis of eyelid Sense Organs 0.999 0.899 – 1.11 0.979 404 1973 exclusion phecode
374.6 Dermatochalasis Sense Organs 0.951 0.859 – 1.05 0.342 430 1859 exclusion phecode
375 Disorders of lacrimal system Sense Organs 0.953 0.898 – 1.01 0.109 1517 4633 exclusion phecode
375.1 Dry eyes Sense Organs 0.973 0.919 – 1.03 0.358 1672 4750 exclusion phecode
375.2 Epiphora Sense Organs 0.919 0.776 – 1.09 0.329 167 816 exclusion phecode
376 Disorders of the orbit Sense Organs 1.05 0.82 – 1.33 0.716 77 591 exclusion phecode
377 Disorders of optic nerve and visual pathways Sense Organs 1.04 0.916 – 1.18 0.558 296 1648 exclusion phecode
377.1 Optic atrophy Sense Organs 0.967 0.792 – 1.18 0.741 123 616 exclusion phecode
377.3 Optic neuritis/neuropathy Sense Organs 1.06 0.906 – 1.24 0.462 174 1003 exclusion phecode
378
Strabismus and other disorders of binocular eye
Strabismus and other disorders of binocular eye movements
 Sense Organs 1.03 0.928 – 1.14 0.58 423 2264 exclusion phecode
378.1 Strabismus (not specified as paralytic) Sense Organs 0.981 0.867 – 1.11 0.76 289 1521 exclusion phecode
378.2 Nystagmus and other irregular eye movements Sense Organs 1.11 0.822 – 1.49 0.505 54 303 exclusion phecode
378.5 Paralytic strabismus Sense Organs 0.915 0.739 – 1.13 0.414 96 594 exclusion phecode
379 Other disorders of eye Sense Organs 0.981 0.931 – 1.03 0.474 2101 5291 exclusion phecode
379.1 Scleritis and episcleritis Sense Organs 0.982 0.75 – 1.29 0.897 66 348 exclusion phecode
379.2 Disorders of vitreous body Sense Organs 0.966 0.91 – 1.03 0.26 1562 4216 exclusion phecode
379.3 Aphakia and other disorders of lens Sense Organs 0.831 0.64 – 1.08 0.163 65 299 exclusion phecode
379.4 Anomalies of pupillary function Sense Organs 0.855 0.7 – 1.04 0.126 106 595 exclusion phecode
379.5 Disorders of iris and ciliary body Sense Organs 0.907 0.739 – 1.11 0.348 115 651 exclusion phecode
379.51 Pigmentary iris degeneration Sense Organs 1.09 0.647 – 1.82 0.756 22 111 exclusion phecode
379.9 Pain, swelling or discharge of eye Sense Organs 0.882 0.792 – 0.982 0.0225 404 1996 exclusion phecode
380 Disorders of external ear Sense Organs 0.994 0.927 – 1.07 0.869 981 4293 exclusion phecode
380.1 Otitis externa Sense Organs 0.964 0.881 – 1.05 0.42 578 3124 exclusion phecode
380.4 Impacted cerumen Sense Organs 1.01 0.943 – 1.07 0.858 1172 4895 exclusion phecode
381 Otitis media and Eustachian tube disorders Sense Organs 0.992 0.936 – 1.05 0.776 1408 6837 exclusion phecode
381.1 Otitis media Sense Organs 1.02 0.954 – 1.09 0.535 995 5630 exclusion phecode
381.11 Suppurative and unspecified otitis media Sense Organs 1.02 0.948 – 1.1 0.571 840 4876 exclusion phecode
381.2 Eustachian tube disorders Sense Organs 0.951 0.875 – 1.03 0.243 665 3656 exclusion phecode
381.3 Mastoiditis & related conditions Sense Organs 1.07 0.763 – 1.5 0.691 36 299 exclusion phecode
381.9 Otorrhea Sense Organs 0.976 0.783 – 1.22 0.832 92 686 exclusion phecode
382 Otalgia Sense Organs 1.01 0.926 – 1.09 0.875 668 3697 exclusion phecode
383 Otosclerosis Sense Organs 0.969 0.641 – 1.47 0.883 19 221 exclusion phecode
384 Other disorders of tympanic membrane Sense Organs 1.01 0.845 – 1.22 0.881 133 932 exclusion phecode
384.1 Myringitis Sense Organs 0.861 0.517 – 1.43 0.565 14 102 exclusion phecode
384.4 Perforation of tympanic membrane Sense Organs 1.01 0.816 – 1.25 0.942 99 727 exclusion phecode
385 Other disorders of middle ear and mastoid Sense Organs 1.21 0.959 – 1.51 0.109 87 749 exclusion phecode
385.3 Cholesteatoma Sense Organs 1.34 0.968 – 1.87 0.0771 41 449 exclusion phecode
385.5
Tympanosclerosis and middle ear disease related
Tympanosclerosis and middle ear disease related to otitis media
 Sense Organs 0.793 0.524 – 1.2 0.274 25 208 exclusion phecode
386
Vertiginous syndromes and other disorders of
Vertiginous syndromes and other disorders of vestibular system
 Sense Organs 1.01 0.931 – 1.1 0.78 695 3334 exclusion phecode
386.1 Meniere's disease Sense Organs 1.14 0.916 – 1.43 0.236 93 608 exclusion phecode
386.2 Peripheral or central vertigo Sense Organs 1.04 0.948 – 1.13 0.438 603 2850 exclusion phecode
386.21 Central origin vertigo Sense Organs 1.09 0.982 – 1.21 0.108 453 2198 exclusion phecode
386.3 Labyrinthitis Sense Organs 1.06 0.966 – 1.16 0.216 540 2695 exclusion phecode
386.9
Dizziness and giddiness (Light-headedness and
Dizziness and giddiness (Light-headedness and vertigo)
 Sense Organs 1.02 0.977 – 1.07 0.339 2621 6767 exclusion phecode
388 Other disorders of ear Sense Organs 1.02 0.909 – 1.16 0.688 317 1867 exclusion phecode
389 Hearing loss Sense Organs 1.03 0.985 – 1.08 0.183 2596 6848 exclusion phecode
389.1 Sensorineural hearing loss Sense Organs 0.976 0.919 – 1.04 0.423 1458 5314 exclusion phecode
389.2 Conductive hearing loss Sense Organs 1.03 0.897 – 1.18 0.681 238 1661 exclusion phecode
389.3 Degenerative and vascular disorders of ear Sense Organs 0.764 0.606 – 0.964 0.0231 87 385 exclusion phecode
389.4 Tinnitus Sense Organs 0.987 0.913 – 1.07 0.742 755 4233 exclusion phecode
389.5 Disorders of acoustic nerve Sense Organs 1.19 0.841 – 1.68 0.327 38 203 exclusion phecode
394 Rheumatic disease of the heart valves Circulatory System 1.05 0.967 – 1.14 0.251 818 2497 exclusion phecode
394.1 Mitral valve stenosis and aortic valve stenosis Circulatory System 1.04 0.888 – 1.21 0.66 223 686 exclusion phecode
394.2 Mitral valve disease Circulatory System 1.01 0.874 – 1.16 0.921 253 833 exclusion phecode
394.3 Aortic valve disease Circulatory System 1.11 0.891 – 1.38 0.357 118 313 exclusion phecode
394.4 Acute rheumatic heart disease Circulatory System 0.684 0.44 – 1.06 0.0922 28 84 exclusion phecode
394.7 Disease of tricuspid valve Circulatory System 1.08 0.953 – 1.23 0.225 342 992 exclusion phecode
395 Heart valve disorders Circulatory System 1.12 1.06 – 1.18 7.14e-05 1781 5007 exclusion phecode
395.1 Nonrheumatic mitral valve disorders Circulatory System 1.09 1.02 – 1.18 0.0157 944 3695 exclusion phecode
395.2 Nonrheumatic aortic valve disorders Circulatory System 1.15 1.07 – 1.23 0.000152 1106 3153 exclusion phecode
395.3 Nonrheumatic tricuspid valve disorders Circulatory System 1.11 0.967 – 1.27 0.14 271 916 exclusion phecode
395.4 Nonrheumatic pulmonary valve disorders Circulatory System 1.05 0.739 – 1.48 0.798 49 220 exclusion phecode
395.6 Heart valve replaced Circulatory System 1.11 1.01 – 1.22 0.0253 632 1913 exclusion phecode
396 Abnormal heart sounds Circulatory System 1.1 1.04 – 1.16 0.000732 1701 6102 exclusion phecode
401 Hypertension Circulatory System 1.09 1.03 – 1.14 0.0012 6218 3441 exclusion phecode
401.1 Essential hypertension Circulatory System 1.09 1.03 – 1.14 0.0014 6184 3441 exclusion phecode
401.2 Hypertensive heart and/or renal disease Circulatory System 1.18 1.1 – 1.27 5.49e-06 1824 1963 exclusion phecode
401.21 Hypertensive heart disease Circulatory System 1.19 1.07 – 1.34 0.00184 503 865 exclusion phecode
401.22 Hypertensive chronic kidney disease Circulatory System 1.17 1.08 – 1.26 0.000108 1331 1724 exclusion phecode
401.3 Other hypertensive complications Circulatory System 1.18 1.09 – 1.27 1.4e-05 1319 2190 exclusion phecode
411 Ischemic Heart Disease Circulatory System 1.22 1.16 – 1.28 4.13e-15 3542 4571 exclusion phecode
411.1 Unstable angina (intermediate coronary syndrome) Circulatory System 1.28 1.16 – 1.41 1.75e-06 623 1458 exclusion phecode
411.2 Myocardial infarction Circulatory System 1.23 1.15 – 1.31 8.9e-10 1481 3181 exclusion phecode
411.3 Angina pectoris Circulatory System 1.25 1.17 – 1.34 1.91e-10 1377 2730 exclusion phecode
411.4 Coronary atherosclerosis Circulatory System 1.22 1.16 – 1.28 5.1e-14 3191 4127 exclusion phecode
411.41 Aneurysm and dissection of heart Circulatory System 1.47 1.12 – 1.92 0.00529 103 261 exclusion phecode
411.8
Other chronic ischemic heart disease
Other chronic ischemic heart disease, unspecified
 Circulatory System 1.23 1.17 – 1.3 3e-14 2730 3819 exclusion phecode
411.9
Other acute and subacute forms of ischemic
Other acute and subacute forms of ischemic heart disease
 Circulatory System 1.24 1.07 – 1.44 0.00438 270 766 exclusion phecode
414 Other forms of chronic heart disease Circulatory System 1.24 1.17 – 1.32 1.14e-11 1601 3367 exclusion phecode
414.2 ASCVD Circulatory System 1.11 0.986 – 1.25 0.0835 428 1190 exclusion phecode
415 Pulmonary heart disease Circulatory System 1.08 1.01 – 1.14 0.0182 1283 5664 exclusion phecode
415.1 Acute pulmonary heart disease Circulatory System 1.07 0.98 – 1.17 0.132 598 3595 exclusion phecode
415.11 Pulmonary embolism and infarction, acute Circulatory System 1.07 0.98 – 1.17 0.132 594 3582 exclusion phecode
415.2 Chronic pulmonary heart disease Circulatory System 1.1 1.02 – 1.19 0.0125 884 3616 exclusion phecode
415.21 Primary pulmonary hypertension Circulatory System 1.09 0.966 – 1.23 0.162 370 1449 exclusion phecode
416 Cardiomegaly Circulatory System 0.962 0.881 – 1.05 0.385 635 2573 exclusion phecode
418 Nonspecific chest pain Circulatory System 1.03 0.984 – 1.07 0.224 4841 4792 exclusion phecode
418.1 Precordial pain Circulatory System 1.06 0.973 – 1.16 0.178 699 2093 exclusion phecode
420 Carditis Circulatory System 1.06 0.977 – 1.15 0.159 742 3111 exclusion phecode
420.1 Myocarditis Circulatory System 1.14 0.834 – 1.57 0.402 49 193 exclusion phecode
420.2 Pericarditis Circulatory System 0.982 0.878 – 1.1 0.746 376 1611 exclusion phecode
420.21 Acute pericarditis Circulatory System 0.992 0.773 – 1.27 0.949 86 315 exclusion phecode
420.22 Chronic pericarditis Circulatory System 0.99 0.723 – 1.36 0.95 61 205 exclusion phecode
420.3 Endocarditis Circulatory System 1.04 0.93 – 1.17 0.477 388 1542 exclusion phecode
425 Cardiomyopathy Circulatory System 1.13 1.05 – 1.21 0.000721 1064 3986 exclusion phecode
425.1 Primary/intrinsic cardiomyopathies Circulatory System 1.11 1.04 – 1.19 0.00285 1032 3842 exclusion phecode
425.11 Hypertrophic obstructive cardiomyopathy Circulatory System 0.954 0.762 – 1.19 0.679 103 429 exclusion phecode
425.12 Other hypertrophic cardiomyopathy Circulatory System 1.23 0.959 – 1.57 0.103 81 364 exclusion phecode
425.2 Secondary/extrinsic cardiomyopathies Circulatory System 1.03 0.866 – 1.21 0.772 166 675 exclusion phecode
425.8 Other cardiomyopathy Circulatory System 0.887 0.639 – 1.23 0.476 46 159 exclusion phecode
426 Cardiac conduction disorders Circulatory System 1.09 1.03 – 1.15 0.00138 4609 3177 exclusion phecode
426.2 Atrioventricular [AV] block Circulatory System 1.1 1 – 1.21 0.04 947 1279 exclusion phecode
426.21 First degree AV block Circulatory System 1.11 1 – 1.24 0.0501 655 984 exclusion phecode
426.22 Mobitz II AV block Circulatory System 0.886 0.61 – 1.29 0.524 38 75 exclusion phecode
426.23 Second degree AV block Circulatory System 1.16 0.936 – 1.45 0.172 122 254 exclusion phecode
426.24 Atrioventricular block, complete Circulatory System 1.17 0.989 – 1.37 0.0677 265 449 exclusion phecode
426.25 Other heart block Circulatory System 0.964 0.731 – 1.27 0.797 108 214 exclusion phecode
426.3 Bundle branch block Circulatory System 1.11 1.02 – 1.21 0.0129 1025 1573 exclusion phecode
426.31 Right bundle branch block Circulatory System 1.09 0.989 – 1.21 0.0812 615 1207 exclusion phecode
426.32 Left bundle branch block Circulatory System 1.06 0.943 – 1.18 0.348 483 945 exclusion phecode
426.4 Anomalous atrioventricular excitation Circulatory System 0.949 0.554 – 1.62 0.848 20 80 exclusion phecode
426.7 Abnormal electrocardiogram [ECG] [EKG] Circulatory System 1.09 1.03 – 1.15 0.00135 4182 3155 exclusion phecode
426.8 Other cardiac conduction disorders Circulatory System 1.08 0.948 – 1.23 0.252 334 857 exclusion phecode
426.9 Cardiac pacemaker/device in situ Circulatory System 1.15 1.04 – 1.26 0.00444 799 1301 exclusion phecode
426.91 Cardiac pacemaker in situ Circulatory System 1.12 0.998 – 1.25 0.0549 527 914 exclusion phecode
426.92 Cardiac defibrillator in situ Circulatory System 1.17 1.04 – 1.32 0.00843 468 847 exclusion phecode
427 Cardiac dysrhythmias Circulatory System 1.07 1.02 – 1.13 0.00354 5493 3254 exclusion phecode
427.1 Paroxysmal tachycardia, unspecified Circulatory System 1.15 1.06 – 1.24 0.000776 1058 2099 exclusion phecode
427.11 Paroxysmal supraventricular tachycardia Circulatory System 1.13 1.03 – 1.25 0.013 601 1627 exclusion phecode
427.12 Paroxysmal ventricular tachycardia Circulatory System 1.19 1.07 – 1.32 0.00106 624 1182 exclusion phecode
427.2 Atrial fibrillation and flutter Circulatory System 1.13 1.05 – 1.21 0.00105 2013 2138 exclusion phecode
427.21 Atrial fibrillation Circulatory System 1.12 1.05 – 1.21 0.00133 1972 2090 exclusion phecode
427.22 Atrial flutter Circulatory System 1.1 0.994 – 1.21 0.0643 764 1206 exclusion phecode
427.3 Other specified cardiac dysrhythmias Circulatory System 1.1 1.04 – 1.16 0.00144 3224 3171 exclusion phecode
427.4 Cardiac arrest and ventricular fibrillation Circulatory System 1.14 0.981 – 1.31 0.089 270 627 exclusion phecode
427.41 Ventricular fibrillation and flutter Circulatory System 1.36 1.07 – 1.74 0.0133 125 292 exclusion phecode
427.42 Cardiac arrest Circulatory System 1.08 0.919 – 1.27 0.351 204 501 exclusion phecode
427.5 Arrhythmia (cardiac) NOS Circulatory System 1.09 1.02 – 1.15 0.00645 2442 3146 exclusion phecode
427.6 Premature beats Circulatory System 1.11 1.02 – 1.21 0.0111 1033 1948 exclusion phecode
427.61 Supraventricular premature beats Circulatory System 1.09 0.949 – 1.26 0.218 309 774 exclusion phecode
427.7 Tachycardia NOS Circulatory System 1.09 1.03 – 1.16 0.00431 1836 3185 exclusion phecode
427.8 Sinoatrial node dysfunction (Bradycardia) Circulatory System 1.1 0.969 – 1.24 0.146 440 822 exclusion phecode
427.9 Palpitations Circulatory System 1.06 0.997 – 1.13 0.0622 1748 3146 exclusion phecode
428 Congestive heart failure; nonhypertensive Circulatory System 1.16 1.09 – 1.23 1.46e-06 2080 3117 exclusion phecode
428.1 Congestive heart failure (CHF) NOS Circulatory System 1.17 1.1 – 1.25 7.86e-07 1808 2929 exclusion phecode
428.2 Heart failure NOS Circulatory System 1.15 1.08 – 1.22 1.79e-05 1810 2822 exclusion phecode
428.3
Heart failure with reduced EF [Systolic or
Heart failure with reduced EF [Systolic or combined heart failure]
 Circulatory System 1.22 1.13 – 1.33 5.65e-07 1027 1937 exclusion phecode
428.4
Heart failure with preserved EF [Diastolic
Heart failure with preserved EF [Diastolic heart failure]
 Circulatory System 1.09 1 – 1.18 0.0407 932 1778 exclusion phecode
429
Ill-defined descriptions and complications of
Ill-defined descriptions and complications of heart disease
 Circulatory System 1.1 1.05 – 1.15 2.24e-05 4681 4529 exclusion phecode
429.1 Heart transplant/surgery Circulatory System 1.15 1.05 – 1.27 0.00264 669 1550 exclusion phecode
429.2 Abnormal function study of cardiovascular system Circulatory System 1.11 1.05 – 1.17 0.000101 2766 4064 exclusion phecode
429.3 Symptoms involving cardiovascular system Circulatory System 1.1 1.05 – 1.16 3.18e-05 3645 4527 exclusion phecode
429.9 Cardiac complications, not elsewhere classified Circulatory System 1.15 1.02 – 1.3 0.0278 348 884 exclusion phecode
430 Intracranial hemorrhage Circulatory System 1.09 0.955 – 1.25 0.2 262 1573 exclusion phecode
430.1 Subarachnoid hemorrhage Circulatory System 1.14 0.898 – 1.44 0.284 89 477 exclusion phecode
430.2 Intracerebral hemorrhage Circulatory System 1.12 0.915 – 1.37 0.271 116 661 exclusion phecode
430.3 Subdural hemorrhage Circulatory System 1.05 0.849 – 1.3 0.649 102 568 exclusion phecode
433 Cerebrovascular disease Circulatory System 1.09 1.04 – 1.15 0.00121 1974 5967 exclusion phecode
433.1 Occlusion and stenosis of precerebral arteries Circulatory System 1.08 1 – 1.16 0.0483 907 3195 exclusion phecode
433.11
Occlusion of cerebral arteries, with cerebral
Occlusion of cerebral arteries, with cerebral infarction
 Circulatory System 1.15 0.948 – 1.39 0.157 132 551 exclusion phecode
433.12 Cerebral atherosclerosis Circulatory System 1.15 0.798 – 1.65 0.459 49 181 exclusion phecode
433.2 Occlusion of cerebral arteries Circulatory System 1.1 1.02 – 1.18 0.0104 895 4145 exclusion phecode
433.21
Cerebral artery occlusion, with cerebral
Cerebral artery occlusion, with cerebral infarction
 Circulatory System 1.1 1.02 – 1.19 0.0114 868 4020 exclusion phecode
433.3 Cerebral ischemia Circulatory System 1.07 0.997 – 1.14 0.0597 1077 4352 exclusion phecode
433.31 Transient cerebral ischemia Circulatory System 1.05 0.98 – 1.13 0.161 944 3957 exclusion phecode
433.5 Cerebral aneurysm Circulatory System 1.07 0.877 – 1.31 0.492 110 788 exclusion phecode
433.6 Acute, but ill-defined cerebrovascular disease Circulatory System 0.988 0.86 – 1.14 0.866 283 1004 exclusion phecode
433.8 Late effects of cerebrovascular disease Circulatory System 1.1 0.967 – 1.24 0.151 321 1355 exclusion phecode
440 Atherosclerosis Circulatory System 1.09 1.02 – 1.17 0.00752 1322 3265 exclusion phecode
440.1 Atherosclerosis of renal artery Circulatory System 1.2 0.971 – 1.49 0.0909 118 343 exclusion phecode
440.2 Atherosclerosis of the extremities Circulatory System 1.07 0.988 – 1.16 0.0984 866 2432 exclusion phecode
440.21
Atherosclerosis of native arteries of the
Atherosclerosis of native arteries of the extremities with ulceration or gangrene
 Circulatory System 1.19 1 – 1.41 0.045 184 651 exclusion phecode
440.22
Atherosclerosis of native arteries of the
Atherosclerosis of native arteries of the extremities with intermittent claudication
 Circulatory System 1.06 0.963 – 1.16 0.251 627 1828 exclusion phecode
440.9 Atherosclerosis of aorta Circulatory System 1.15 1.03 – 1.28 0.00983 475 1362 exclusion phecode
441 Vascular insufficiency of intestine Circulatory System 0.916 0.789 – 1.06 0.248 231 883 exclusion phecode
441.1 Acute vascular insufficiency of intestine Circulatory System 0.919 0.745 – 1.13 0.432 112 418 exclusion phecode
441.2 Chronic vascular insufficiency of intestine Circulatory System 0.952 0.726 – 1.25 0.722 64 277 exclusion phecode
442 Other aneurysm Circulatory System 1.08 1.01 – 1.16 0.0266 1158 3401 exclusion phecode
442.1 Aortic aneurysm Circulatory System 1.08 0.999 – 1.16 0.053 940 2672 exclusion phecode
442.11 Abdominal aortic aneurysm Circulatory System 1.16 1.04 – 1.28 0.00499 509 1708 exclusion phecode
442.2 Aneurysm of iliac artery Circulatory System 1.2 0.943 – 1.52 0.14 90 304 exclusion phecode
442.3 Aneurysm of artery of lower extremity Circulatory System 1.29 0.994 – 1.67 0.0555 83 266 exclusion phecode
442.4 Arterial dissection Circulatory System 0.971 0.766 – 1.23 0.807 85 271 exclusion phecode
442.8 Aneurysm of other specified artery Circulatory System 1.19 0.989 – 1.43 0.0657 148 621 exclusion phecode
443 Peripheral vascular disease Circulatory System 1.12 1.06 – 1.2 0.000258 1382 4093 exclusion phecode
443.1 Raynaud's syndrome Circulatory System 1.04 0.911 – 1.2 0.53 240 1213 exclusion phecode
443.7
Peripheral angiopathy in diseases classified
Peripheral angiopathy in diseases classified elsewhere
 Circulatory System 1.11 0.93 – 1.32 0.253 170 626 exclusion phecode
443.8 Other specified peripheral vascular diseases Circulatory System 1.12 1.05 – 1.2 0.00112 1118 3679 exclusion phecode
443.9 Peripheral vascular disease, unspecified Circulatory System 1.13 1.06 – 1.22 0.000435 1136 3199 exclusion phecode
444 Arterial embolism and thrombosis Circulatory System 1.1 0.983 – 1.23 0.0951 390 1423 exclusion phecode
444.1
Arterial embolism and thrombosis of lower
Arterial embolism and thrombosis of lower extremity artery
 Circulatory System 1.1 0.927 – 1.32 0.268 162 568 exclusion phecode
444.2 Embolism and thrombosis of abdominal aorta Circulatory System 1.24 0.937 – 1.64 0.132 76 244 exclusion phecode
446 Polyarteritis nodosa and allied conditions Circulatory System 1.07 0.917 – 1.26 0.374 185 819 exclusion phecode
446.4 Wegener's granulomatosis Circulatory System 1.51 1.06 – 2.17 0.0241 39 193 exclusion phecode
446.5 Giant cell arteritis Circulatory System 1.05 0.715 – 1.55 0.796 33 117 exclusion phecode
446.9 Arteritis NOS Circulatory System 1.01 0.831 – 1.24 0.887 119 542 exclusion phecode
447 Other disorders of arteries and arterioles Circulatory System 1.07 0.998 – 1.14 0.0592 1220 3675 exclusion phecode
447.1 Stricture of artery Circulatory System 1.11 0.96 – 1.28 0.163 255 828 exclusion phecode
447.7 Aortic ectasia Circulatory System 0.989 0.888 – 1.1 0.84 432 1374 exclusion phecode
448 Disease of capillaries Circulatory System 0.963 0.867 – 1.07 0.484 423 2114 exclusion phecode
450 Noninfectious disorders of lymphatic channels Circulatory System 0.958 0.876 – 1.05 0.34 544 4198 exclusion phecode
451 Phlebitis and thrombophlebitis Circulatory System 1.01 0.886 – 1.16 0.854 271 1178 exclusion phecode
451.2
Phlebitis and thrombophlebitis of lower
Phlebitis and thrombophlebitis of lower extremities
 Circulatory System 0.944 0.753 – 1.18 0.618 88 407 exclusion phecode
452 Other venous embolism and thrombosis Circulatory System 1.01 0.947 – 1.07 0.864 1474 4441 exclusion phecode
452.1 Iatrogenic pulmonary embolism and infarction Circulatory System 0.953 0.748 – 1.21 0.696 100 433 exclusion phecode
452.2 Deep vein thrombosis [DVT] Circulatory System 1.01 0.936 – 1.08 0.879 937 3985 exclusion phecode
452.8 Postphlebitic syndrome Circulatory System 0.728 0.53 – 0.999 0.0489 32 224 exclusion phecode
453 Chronic venous hypertension Circulatory System 0.943 0.765 – 1.16 0.583 97 374 exclusion phecode
454 Varicose veins Circulatory System 0.92 0.857 – 0.989 0.0232 973 3757 exclusion phecode
454.1 Varicose veins of lower extremity Circulatory System 0.926 0.859 – 0.998 0.044 876 3296 exclusion phecode
454.11 Varicose veins of lower extremity, symptomtic Circulatory System 0.905 0.827 – 0.989 0.0282 615 2370 exclusion phecode
455 Hemorrhoids Circulatory System 1.04 0.991 – 1.1 0.105 2201 4612 exclusion phecode
456 Chronic venous insufficiency [CVI] Circulatory System 0.928 0.87 – 0.99 0.0228 1277 3892 exclusion phecode
457
Encounter for long-term (current) use of
Encounter for long-term (current) use of anticoagulants, antithrombotics, aspirin
 Circulatory System 1.12 1.03 – 1.22 0.00636 852 2324 exclusion phecode
457.2
Encounter for long-term (current) use of
Encounter for long-term (current) use of antiplatelets/antithrombotics
 Circulatory System 1.13 0.932 – 1.36 0.22 150 506 exclusion phecode
457.3 Encounter for long-term (current) use of aspirin Circulatory System 1.12 1.03 – 1.22 0.00992 802 2236 exclusion phecode
458 Hypotension Circulatory System 1.1 1.04 – 1.16 0.000492 2116 5153 exclusion phecode
458.1 Orthostatic hypotension Circulatory System 1.03 0.942 – 1.13 0.489 625 2289 exclusion phecode
458.2 Iatrogenic hypotension Circulatory System 1.07 0.961 – 1.18 0.228 494 1817 exclusion phecode
458.9 Hypotension NOS Circulatory System 1.1 1.04 – 1.16 0.00045 1940 4994 exclusion phecode
459 Other disorders of circulatory system Circulatory System 1.07 1.02 – 1.13 0.00485 2737 5607 exclusion phecode
459.1 Hemorrhage NOS Circulatory System 1.04 0.917 – 1.17 0.57 347 1451 exclusion phecode
459.7 Blood vessel replaced Circulatory System 1.11 1.01 – 1.23 0.0371 509 1952 exclusion phecode
459.9 Circulatory disease NEC Circulatory System 1.08 1.02 – 1.14 0.00389 2368 5371 exclusion phecode
464 Acute sinusitis Respiratory 0.936 0.887 – 0.987 0.0149 1924 4830 exclusion phecode
465
Acute upper respiratory infections of multiple
Acute upper respiratory infections of multiple or unspecified sites
 Respiratory 0.932 0.893 – 0.972 0.00111 3814 5406 exclusion phecode
465.2 Acute pharyngitis Respiratory 0.947 0.897 – 0.998 0.043 2053 4764 exclusion phecode
465.4 Acute laryngitis and tracheitis Respiratory 0.927 0.774 – 1.11 0.407 147 702 exclusion phecode
470 Septal Deviations/Turbinate Hypertrophy Respiratory 0.946 0.859 – 1.04 0.267 484 2635 exclusion phecode
471 Nasal polyps Respiratory 1.04 0.881 – 1.24 0.624 151 981 exclusion phecode
472 Chronic pharyngitis and nasopharyngitis Respiratory 0.929 0.854 – 1.01 0.0884 689 2867 exclusion phecode
473 Diseases of the larynx and vocal cords Respiratory 0.914 0.846 – 0.986 0.0208 805 3933 exclusion phecode
473.1 Chronic laryngitis Respiratory 0.688 0.465 – 1.02 0.0616 27 120 exclusion phecode
473.3 Paralysis/spasm of vocal cords or larynx Respiratory 1 0.848 – 1.19 0.97 157 952 exclusion phecode
473.4 Voice disturbance Respiratory 0.962 0.883 – 1.05 0.38 627 3351 exclusion phecode
474 Acute and chronic tonsillitis Respiratory 0.916 0.803 – 1.04 0.192 283 1201 exclusion phecode
474.1 Acute tonsillitis Respiratory 0.978 0.784 – 1.22 0.845 104 451 exclusion phecode
474.2 Chronic tonsillitis and adenoiditis Respiratory 0.902 0.775 – 1.05 0.18 214 939 exclusion phecode
475 Chronic sinusitis Respiratory 0.937 0.883 – 0.995 0.0346 1476 4360 exclusion phecode
475.9 Postnasal drip Respiratory 0.918 0.817 – 1.03 0.15 379 1632 exclusion phecode
476 Allergic rhinitis Respiratory 0.923 0.883 – 0.965 0.000453 3676 4423 exclusion phecode
477 Epistaxis or throat hemorrhage Respiratory 1.09 0.982 – 1.21 0.108 490 1877 exclusion phecode
478 Throat pain Respiratory 1 0.82 – 1.22 0.982 127 646 exclusion phecode
479 Other upper respiratory disease Respiratory 0.955 0.904 – 1.01 0.106 1850 4404 exclusion phecode
480 Pneumonia Respiratory 1.04 0.985 – 1.09 0.171 2144 6201 exclusion phecode
480.1 Bacterial pneumonia Respiratory 1.08 0.978 – 1.19 0.125 515 2103 exclusion phecode
480.11 Pneumococcal pneumonia Respiratory 1.1 0.952 – 1.27 0.198 254 1037 exclusion phecode
480.12 Pseudomonal pneumonia Respiratory 1.14 0.857 – 1.52 0.365 76 254 exclusion phecode
480.13 MRSA pneumonia Respiratory 0.94 0.691 – 1.28 0.692 53 240 exclusion phecode
480.2 Viral pneumonia Respiratory 0.986 0.803 – 1.21 0.894 110 448 exclusion phecode
480.3 Pneumonia due to fungus (mycoses) Respiratory 1.24 0.936 – 1.64 0.135 71 309 exclusion phecode
480.5 Bronchopneumonia and lung abscess Respiratory 0.878 0.646 – 1.19 0.408 55 239 exclusion phecode
481 Influenza Respiratory 0.991 0.906 – 1.08 0.836 591 2674 exclusion phecode
483 Acute bronchitis and bronchiolitis Respiratory 0.962 0.908 – 1.02 0.191 1461 5219 exclusion phecode
495 Asthma Respiratory 0.995 0.948 – 1.04 0.841 2235 6145 exclusion phecode
495.1 Chronic obstructive asthma Respiratory 1.02 0.858 – 1.22 0.801 153 787 exclusion phecode
495.11 Chronic obstructive asthma with exacerbation Respiratory 1.24 0.864 – 1.78 0.243 48 206 exclusion phecode
495.2 Asthma with exacerbation Respiratory 0.983 0.898 – 1.08 0.705 573 3051 exclusion phecode
496 Chronic airway obstruction Respiratory 1.03 0.968 – 1.09 0.386 1459 5192 exclusion phecode
496.1 Emphysema Respiratory 1.02 0.94 – 1.12 0.582 612 3619 exclusion phecode
496.2 Chronic bronchitis Respiratory 1.04 0.973 – 1.11 0.256 1144 4873 exclusion phecode
496.21 Obstructive chronic bronchitis Respiratory 1.06 0.987 – 1.13 0.116 1045 4667 exclusion phecode
496.3 Bronchiectasis Respiratory 1.13 0.974 – 1.32 0.105 208 1154 exclusion phecode
497 Bronchitis Respiratory 1.02 0.944 – 1.1 0.599 792 3795 exclusion phecode
498 Acute bronchospasm Respiratory 0.981 0.845 – 1.14 0.802 220 953 exclusion phecode
499 Cystic fibrosis Respiratory 1 0.749 – 1.34 0.989 67 376 exclusion phecode
500 Lung disease due to external agents Respiratory 0.9 0.774 – 1.05 0.173 197 955 exclusion phecode
500.1 Extrinsic allergic alveolitis Respiratory 0.921 0.648 – 1.31 0.645 35 150 exclusion phecode
500.2 Pneumoconiosis Respiratory 0.962 0.693 – 1.33 0.815 35 153 exclusion phecode
501 Pneumonitis due to inhalation of food or vomitus Respiratory 1.07 0.924 – 1.24 0.37 235 1136 exclusion phecode
502 Postinflammatory pulmonary fibrosis Respiratory 0.945 0.835 – 1.07 0.367 308 1442 exclusion phecode
503 Pulmonary congestion and hypostasis Respiratory 1.11 0.995 – 1.24 0.0624 448 1624 exclusion phecode
504 Other alveolar and parietoalveolar pneumonopathy Respiratory 0.969 0.84 – 1.12 0.663 228 1095 exclusion phecode
504.1 Idiopathic fibrosing alveolitis Respiratory 0.999 0.825 – 1.21 0.993 122 579 exclusion phecode
505 Other pulmonary inflamation or edema Respiratory 1.1 1.02 – 1.2 0.0128 834 2901 exclusion phecode
506 Empyema and pneumothorax Respiratory 1.12 1.04 – 1.2 0.00135 1066 4202 exclusion phecode
507 Pleurisy; pleural effusion Respiratory 1.08 1.01 – 1.15 0.0262 1152 4433 exclusion phecode
508
Pulmonary collapse; interstitial and
Pulmonary collapse; interstitial and compensatory emphysema
 Respiratory 1.09 1.01 – 1.17 0.0308 870 3907 exclusion phecode
509 Respiratory failure, insufficiency, arrest Respiratory 1.16 1.09 – 1.23 7.86e-07 1677 4953 exclusion phecode
509.1 Respiratory failure Respiratory 1.1 1.02 – 1.19 0.0154 802 3328 exclusion phecode
509.2 Respiratory insufficiency Respiratory 1.18 1.06 – 1.3 0.00157 513 2058 exclusion phecode
509.3
Pulmonary insufficiency or respiratory failure
Pulmonary insufficiency or respiratory failure following trauma and surgery
 Respiratory 1.12 1.03 – 1.22 0.00551 789 2829 exclusion phecode
509.8
Dependence on respirator [Ventilator] or
Dependence on respirator [Ventilator] or supplemental oxygen
 Respiratory 1.17 1.08 – 1.27 0.000239 717 2991 exclusion phecode
510 Other diseases of lung Respiratory 0.987 0.939 – 1.04 0.617 2036 6644 exclusion phecode
510.2 Lung transplant Respiratory 1.09 0.867 – 1.37 0.464 104 352 exclusion phecode
512 Other symptoms of respiratory system Respiratory 1.01 0.967 – 1.05 0.665 6300 3373 exclusion phecode
512.1 Wheezing Respiratory 0.974 0.884 – 1.07 0.59 613 1758 exclusion phecode
512.2 Painful respiration Respiratory 1.02 0.948 – 1.11 0.536 942 2631 exclusion phecode
512.3 Abnormal chest sounds Respiratory 0.938 0.761 – 1.16 0.551 153 363 exclusion phecode
512.7 Shortness of breath Respiratory 1.04 0.99 – 1.09 0.116 3896 3353 exclusion phecode
512.8 Cough Respiratory 0.979 0.932 – 1.03 0.386 3808 3372 exclusion phecode
512.9 Other dyspnea Respiratory 1.02 0.974 – 1.07 0.355 3994 3364 exclusion phecode
513 Respiratory abnormalities Respiratory 1.04 0.993 – 1.08 0.102 4577 5094 exclusion phecode
513.3 Hypoventilation Respiratory 0.944 0.842 – 1.06 0.326 398 1491 exclusion phecode
513.31 Apnea Respiratory 1.06 0.899 – 1.25 0.489 189 786 exclusion phecode
513.32 Orthopnea Respiratory 0.868 0.694 – 1.08 0.212 123 364 exclusion phecode
513.4 Hyperventilation Respiratory 1.16 0.995 – 1.35 0.0581 239 743 exclusion phecode
513.8 Disorders of diaphragm Respiratory 1.16 0.918 – 1.46 0.216 95 411 exclusion phecode
514 Abnormal findings examination of lungs Respiratory 0.981 0.928 – 1.04 0.5 1588 6667 exclusion phecode
514.1
Abnormal results of function study of pulmonary
Abnormal results of function study of pulmonary system
 Respiratory 0.964 0.79 – 1.18 0.72 120 582 exclusion phecode
514.2 Solitary pulmonary nodule Respiratory 0.993 0.923 – 1.07 0.839 865 5271 exclusion phecode
516 Abnormal sputum Respiratory 1.03 0.91 – 1.18 0.607 281 1611 exclusion phecode
516.1 Hemoptysis Respiratory 1.1 0.958 – 1.27 0.176 232 1327 exclusion phecode
519
Other diseases of respiratory system, not
Other diseases of respiratory system, not elsewhere classified
 Respiratory 1.06 1.01 – 1.11 0.0187 2249 7145 exclusion phecode
519.1 Tracheostomy complications Respiratory 1.21 0.909 – 1.62 0.191 48 355 exclusion phecode
519.2 Respiratory complications Respiratory 1.07 0.907 – 1.27 0.416 169 773 exclusion phecode
519.8 Other diseases of respiratory system, NEC Respiratory 1.02 0.925 – 1.12 0.742 512 3067 exclusion phecode
519.9
Symptoms involving respiratory system and other
Symptoms involving respiratory system and other chest symptoms
 Respiratory 1.08 1.02 – 1.14 0.00654 1721 6322 exclusion phecode
520 Disorders of tooth development Digestive 0.828 0.638 – 1.07 0.156 56 672 exclusion phecode
520.1 Hereditary disturbances in tooth structure Digestive 0.823 0.578 – 1.17 0.279 29 331 exclusion phecode
520.2 Disturbances in tooth eruption Digestive 0.821 0.54 – 1.25 0.358 24 356 exclusion phecode
521 Diseases of hard tissues of teeth Digestive 1.02 0.893 – 1.18 0.729 223 1741 exclusion phecode
521.1 Dental caries Digestive 0.999 0.864 – 1.15 0.984 202 1618 exclusion phecode
521.2 Dental abrasion, erosion and attrition Digestive 1.33 0.762 – 2.34 0.313 17 83 exclusion phecode
522 Diseases of pulp and periapical tissues Digestive 1.06 0.902 – 1.25 0.478 179 1104 exclusion phecode
522.5 Periapical abscess Digestive 1.03 0.872 – 1.22 0.721 166 935 exclusion phecode
523 Gingival and periodontal diseases Digestive 0.943 0.818 – 1.09 0.42 207 1410 exclusion phecode
523.1 Gingivitis Digestive 0.754 0.554 – 1.03 0.072 49 272 exclusion phecode
523.3 Periodontitis (acute or chronic) Digestive 0.962 0.797 – 1.16 0.682 109 710 exclusion phecode
523.31 Acute periodontitis Digestive 0.907 0.733 – 1.12 0.367 88 595 exclusion phecode
523.32 Chronic periodontitis Digestive 1.1 0.769 – 1.56 0.609 32 233 exclusion phecode
524 Dentofacial anomalies, including malocclusion Digestive 0.76 0.538 – 1.07 0.119 40 566 exclusion phecode
524.3 Anomalies of tooth position/malocclusion Digestive 0.778 0.487 – 1.24 0.293 21 325 exclusion phecode
525
Other diseases of the teeth and supporting
Other diseases of the teeth and supporting structures
 Digestive 1.03 0.9 – 1.17 0.7 265 1970 exclusion phecode
525.1 Loss of teeth or edentulism Digestive 1.04 0.819 – 1.33 0.724 72 683 exclusion phecode
526 Diseases of the jaws Digestive 0.94 0.865 – 1.02 0.147 627 4938 exclusion phecode
526.1 Cysts of the jaws Digestive 0.718 0.491 – 1.05 0.0879 33 418 exclusion phecode
526.3 Anomalies of jaw size/symmetry Digestive 0.953 0.652 – 1.39 0.802 27 341 exclusion phecode
526.4 Temporomandibular joint disorders Digestive 0.963 0.865 – 1.07 0.488 385 2778 exclusion phecode
526.41 Temporomandibular joint disorder, unspecified Digestive 0.943 0.835 – 1.07 0.35 291 2172 exclusion phecode
526.42 Arthralgia/ankylosis of temporomandibular joint Digestive 0.917 0.778 – 1.08 0.305 157 1339 exclusion phecode
526.5 Inflammatory conditions of jaw Digestive 0.824 0.6 – 1.13 0.233 39 539 exclusion phecode
526.8 Exostosis of jaw Digestive 0.882 0.452 – 1.72 0.713 10 102 exclusion phecode
526.9 Jaw disease NOS Digestive 0.823 0.661 – 1.03 0.082 82 944 exclusion phecode
527 Diseases of the salivary glands Digestive 1.03 0.934 – 1.13 0.581 472 3605 exclusion phecode
527.1 Hypertrophy of salivary gland Digestive 0.929 0.553 – 1.56 0.78 17 128 exclusion phecode
527.2 Sialoadenitis Digestive 1.07 0.884 – 1.31 0.47 114 782 exclusion phecode
527.7 Disturbance of salivary secretion Digestive 1.03 0.906 – 1.17 0.656 268 1945 exclusion phecode
527.8 Other specified diseases of the salivary glands Digestive 1.06 0.807 – 1.38 0.687 59 494 exclusion phecode
528
Diseases of the oral soft tissues, excluding
Diseases of the oral soft tissues, excluding lesions specific for gingiva and tongue
 Digestive 0.967 0.893 – 1.05 0.398 698 5234 exclusion phecode
528.1 Stomatitis and mucositis Digestive 0.849 0.737 – 0.977 0.0226 215 1333 exclusion phecode
528.11 Stomatitis and mucositis (ulcerative) Digestive 0.779 0.611 – 0.994 0.0446 67 401 exclusion phecode
528.12 Oral aphthae Digestive 0.812 0.644 – 1.02 0.0793 89 479 exclusion phecode
528.3 Cellulitis and abscess of oral soft tissues Digestive 0.935 0.7 – 1.25 0.65 47 425 exclusion phecode
528.4 Cysts of oral soft tissues Digestive 1.17 0.756 – 1.8 0.485 22 225 exclusion phecode
528.41 Cyst of the salivary gland Digestive 0.859 0.516 – 1.43 0.557 16 139 exclusion phecode
528.5 Diseases of lips Digestive 0.913 0.763 – 1.09 0.319 148 966 exclusion phecode
528.6 Leukoplakia of oral mucosa Digestive 0.927 0.634 – 1.35 0.694 24 277 exclusion phecode
528.7 Sialolithiasis Digestive 1.6 1.17 – 2.19 0.00336 47 301 exclusion phecode
529 Diseases and other conditions of the tongue Digestive 1.02 0.873 – 1.18 0.837 182 1436 exclusion phecode
529.1 Glossitis Digestive 1.03 0.755 – 1.41 0.846 42 245 exclusion phecode
529.6 Glossodynia Digestive 0.938 0.674 – 1.31 0.705 43 360 exclusion phecode
530 Diseases of esophagus Digestive 0.977 0.937 – 1.02 0.29 4685 4629 exclusion phecode
530.1 Esophagitis, GERD and related diseases Digestive 0.978 0.937 – 1.02 0.304 4584 4629 exclusion phecode
530.11 GERD Digestive 0.974 0.934 – 1.02 0.233 4466 4628 exclusion phecode
530.12 Ulcer of esophagus Digestive 0.914 0.759 – 1.1 0.341 155 702 exclusion phecode
530.13 Barrett's esophagus Digestive 0.931 0.805 – 1.08 0.331 214 1320 exclusion phecode
530.14 Reflux esophagitis Digestive 0.915 0.844 – 0.992 0.031 747 3050 exclusion phecode
530.15 Eosinophilic esophagitis Digestive 0.72 0.547 – 0.947 0.0187 66 369 exclusion phecode
530.2 Esophageal bleeding (varices/hemorrhage) Digestive 0.981 0.855 – 1.13 0.786 247 1130 exclusion phecode
530.3 Stricture and stenosis of esophagus Digestive 0.924 0.808 – 1.06 0.253 257 1468 exclusion phecode
530.5 Disorders of esophageal motility Digestive 1.05 0.886 – 1.25 0.558 161 916 exclusion phecode
530.6 Diverticulum of esophagus, acquired Digestive 1.56 0.89 – 2.74 0.12 16 208 exclusion phecode
530.7 Gastroesophageal laceration-hemorrhage syndrome Digestive 0.709 0.508 – 0.99 0.0436 39 157 exclusion phecode
530.9 Heartburn Digestive 0.938 0.853 – 1.03 0.192 520 2574 exclusion phecode
531 Peptic ulcer (excl. esophageal) Digestive 1 0.927 – 1.08 0.952 756 4293 exclusion phecode
531.1 Hemorrhage from gastrointestinal ulcer Digestive 0.975 0.834 – 1.14 0.746 172 806 exclusion phecode
531.2 Gastric ulcer Digestive 1 0.903 – 1.11 0.983 439 2531 exclusion phecode
531.3 Duodenal ulcer Digestive 1.01 0.866 – 1.18 0.891 191 978 exclusion phecode
531.4 Peptic ulcer, site unspecified Digestive 0.935 0.83 – 1.05 0.267 316 1750 exclusion phecode
531.5 Gastrojejunal ulcer Digestive 1.19 0.9 – 1.57 0.224 59 279 exclusion phecode
532 Dysphagia Digestive 0.97 0.915 – 1.03 0.312 1608 4368 exclusion phecode
535 Gastritis and duodenitis Digestive 0.988 0.924 – 1.06 0.721 1061 5159 exclusion phecode
535.1 Acute gastritis Digestive 0.998 0.898 – 1.11 0.974 420 2326 exclusion phecode
535.2 Atrophic gastritis Digestive 0.965 0.789 – 1.18 0.724 118 616 exclusion phecode
535.6 Duodenitis Digestive 1.03 0.853 – 1.24 0.765 138 663 exclusion phecode
535.8 Other specified gastritis Digestive 0.879 0.767 – 1.01 0.0626 261 1292 exclusion phecode
535.9 Gastritis and duodenitis, NOS Digestive 0.947 0.86 – 1.04 0.269 500 2461 exclusion phecode
536 Disorders of function of stomach Digestive 0.997 0.933 – 1.07 0.926 1084 5166 exclusion phecode
536.3 Gastroparesis Digestive 1.22 1.07 – 1.38 0.00268 303 1647 exclusion phecode
536.7
Complications of gastrostomy, colostomy and
Complications of gastrostomy, colostomy and enterostomy
 Digestive 1.11 0.901 – 1.36 0.336 108 637 exclusion phecode
536.8
Dyspepsia and other specified disorders of
Dyspepsia and other specified disorders of function of stomach
 Digestive 0.941 0.872 – 1.02 0.116 823 4075 exclusion phecode
537 Other disorders of stomach and duodenum Digestive 1.08 1.01 – 1.14 0.018 1292 5626 exclusion phecode
537.1 Lesions of stomach and duodenum Digestive 0.947 0.753 – 1.19 0.643 94 379 exclusion phecode
539 Bariatric surgery Digestive 0.926 0.846 – 1.01 0.0895 574 2926 exclusion phecode
540 Appendiceal conditions Digestive 0.993 0.839 – 1.17 0.932 176 1004 exclusion phecode
540.1 Appendicitis Digestive 1 0.839 – 1.2 0.965 153 853 exclusion phecode
540.11 Acute appendicitis Digestive 0.988 0.811 – 1.2 0.905 126 718 exclusion phecode
550 Abdominal hernia Digestive 0.973 0.926 – 1.02 0.285 2113 7060 exclusion phecode
550.1 Inguinal hernia Digestive 0.913 0.836 – 0.998 0.0449 600 3158 exclusion phecode
550.2 Diaphragmatic hernia Digestive 0.963 0.895 – 1.04 0.308 844 4953 exclusion phecode
550.3 Femoral hernia Digestive 0.828 0.6 – 1.14 0.253 43 246 exclusion phecode
550.4 Umbilical hernia Digestive 0.959 0.866 – 1.06 0.416 473 2487 exclusion phecode
550.5 Ventral hernia Digestive 1.04 0.959 – 1.12 0.361 737 4045 exclusion phecode
550.6 Incisional hernia Digestive 1.06 0.955 – 1.17 0.276 414 2424 exclusion phecode
555
Inflammatory bowel disease and other
Inflammatory bowel disease and other gastroenteritis and colitis
 Digestive 1.05 0.944 – 1.17 0.359 411 2189 exclusion phecode
555.1 Regional enteritis Digestive 1.06 0.918 – 1.22 0.432 245 1242 exclusion phecode
555.2 Ulcerative colitis Digestive 1.05 0.919 – 1.21 0.448 264 1362 exclusion phecode
555.21 Ulcerative colitis (chronic) Digestive 1.02 0.855 – 1.21 0.863 171 765 exclusion phecode
556 Ulceration of the lower GI tract Digestive 0.931 0.809 – 1.07 0.323 274 1013 exclusion phecode
556.1 Ulceration of intestine Digestive 0.948 0.814 – 1.1 0.487 238 856 exclusion phecode
556.11
Angiodysplasia of intestine (without mention of
Angiodysplasia of intestine (without mention of hemorrhage)
 Digestive 0.886 0.707 – 1.11 0.292 109 397 exclusion phecode
557 Intestinal malabsorption (non-celiac) Digestive 0.892 0.819 – 0.971 0.00826 704 2540 exclusion phecode
557.1 Celiac disease Digestive 0.917 0.756 – 1.11 0.374 143 697 exclusion phecode
558 Noninfectious gastroenteritis Digestive 0.991 0.927 – 1.06 0.791 1195 3873 exclusion phecode
559 Ileostomy status Digestive 1.13 0.981 – 1.31 0.0888 233 1200 exclusion phecode
560 Intestinal obstruction without mention of hernia Digestive 0.965 0.897 – 1.04 0.344 952 3476 exclusion phecode
560.1 Paralytic ileus Digestive 1.02 0.919 – 1.12 0.753 492 2136 exclusion phecode
560.2 Impaction of intestine Digestive 0.773 0.638 – 0.936 0.00848 147 612 exclusion phecode
560.3 Peritoneal or intestinal adhesions Digestive 0.95 0.757 – 1.19 0.656 97 365 exclusion phecode
560.4 Other intestinal obstruction Digestive 0.949 0.865 – 1.04 0.276 559 2229 exclusion phecode
561 Symptoms involving digestive system Digestive 0.919 0.851 – 0.992 0.0295 876 3234 exclusion phecode
562 Diverticulosis and diverticulitis Digestive 0.909 0.859 – 0.961 0.000865 2298 3398 exclusion phecode
562.1 Diverticulosis Digestive 0.912 0.862 – 0.964 0.00129 2280 3388 exclusion phecode
562.2 Diverticulitis Digestive 0.864 0.783 – 0.954 0.00374 517 2200 exclusion phecode
564 Functional digestive disorders Digestive 0.977 0.933 – 1.02 0.319 3517 4203 exclusion phecode
564.1 Irritable Bowel Syndrome Digestive 0.963 0.896 – 1.03 0.297 990 3327 exclusion phecode
564.9 Personal history of diseases of digestive system Digestive 0.962 0.895 – 1.03 0.282 1030 3645 exclusion phecode
565 Anal and rectal conditions Digestive 1.02 0.954 – 1.08 0.606 1212 5239 exclusion phecode
565.1 Anal and rectal polyp Digestive 1.01 0.919 – 1.11 0.822 522 2405 exclusion phecode
567 Peritonitis and retroperitoneal infections Digestive 1.01 0.916 – 1.12 0.78 456 2047 exclusion phecode
568 Other disorders of peritoneum Digestive 1.01 0.915 – 1.11 0.85 471 2685 exclusion phecode
568.1
Peritoneal adhesions (postoperative)
Peritoneal adhesions (postoperative) (postinfection)
 Digestive 0.971 0.86 – 1.1 0.635 316 1918 exclusion phecode
569 Other disorders of intestine Digestive 1 0.958 – 1.05 0.89 2786 5893 exclusion phecode
569.1 Toxic gastroenteritis and colitis Digestive 1.13 0.917 – 1.39 0.25 114 537 exclusion phecode
569.2 Gastrointestinal complications Digestive 1.03 0.929 – 1.14 0.581 456 2294 exclusion phecode
571 Chronic liver disease and cirrhosis Digestive 1.01 0.953 – 1.07 0.782 1600 5284 exclusion phecode
571.5 Other chronic nonalcoholic liver disease Digestive 1 0.946 – 1.06 0.946 1506 5231 exclusion phecode
571.51 Cirrhosis of liver without mention of alcohol Digestive 1.07 0.96 – 1.19 0.228 406 1816 exclusion phecode
571.6 Primary biliary cirrhosis Digestive 0.919 0.718 – 1.18 0.505 77 325 exclusion phecode
571.8
Liver abscess and sequelae of chronic liver
Liver abscess and sequelae of chronic liver disease
 Digestive 1.1 0.984 – 1.23 0.095 377 1678 exclusion phecode
571.81 Portal hypertension Digestive 1.03 0.901 – 1.18 0.654 252 1014 exclusion phecode
572 Ascites (non malignant) Digestive 1.05 0.967 – 1.13 0.264 770 3606 exclusion phecode
573 Other disorders of liver Digestive 0.983 0.932 – 1.04 0.525 1837 5497 exclusion phecode
573.1 Chronic passive congestion of liver Digestive 1.05 0.796 – 1.37 0.746 92 227 exclusion phecode
573.2 Liver replaced by transplant Digestive 1.1 0.916 – 1.33 0.304 162 494 exclusion phecode
573.3 Hepatomegaly Digestive 0.879 0.736 – 1.05 0.157 137 880 exclusion phecode
573.4 Acute and subacute necrosis of liver Digestive 1.11 0.921 – 1.35 0.265 144 547 exclusion phecode
573.5 Jaundice (not of newborn) Digestive 1.02 0.909 – 1.14 0.757 375 1678 exclusion phecode
573.6
Nonspecific elevation of levels of transaminase
Nonspecific elevation of levels of transaminase or lactic acid dehydrogenase [LDH]
 Digestive 1.05 0.98 – 1.12 0.177 1180 4499 exclusion phecode
573.7 Abnormal results of function study of liver Digestive 1 0.941 – 1.07 0.965 1287 4674 exclusion phecode
573.9 Abnormal serum enzyme levels Digestive 1.06 1 – 1.11 0.0395 1962 5555 exclusion phecode
574 Cholelithiasis and cholecystitis Digestive 0.963 0.903 – 1.03 0.241 1106 6052 exclusion phecode
574.1 Cholelithiasis Digestive 0.951 0.89 – 1.02 0.137 1022 5683 exclusion phecode
574.11 Cholelithiasis with acute cholecystitis Digestive 0.864 0.721 – 1.03 0.111 139 701 exclusion phecode
574.12 Cholelithiasis with other cholecystitis Digestive 0.99 0.845 – 1.16 0.899 180 1091 exclusion phecode
574.2 Calculus of bile duct Digestive 0.996 0.882 – 1.12 0.947 319 1705 exclusion phecode
574.3 Cholecystitis without cholelithiasis Digestive 0.972 0.865 – 1.09 0.627 325 1705 exclusion phecode
575 Other biliary tract disease Digestive 1 0.926 – 1.08 0.998 780 4392 exclusion phecode
575.1 Cholangitis Digestive 1.19 0.981 – 1.44 0.0779 133 706 exclusion phecode
575.2 Obstruction of bile duct Digestive 1.03 0.883 – 1.21 0.685 192 1199 exclusion phecode
575.6 Cholesterolosis of gallbladder Digestive 0.965 0.744 – 1.25 0.789 62 381 exclusion phecode
575.7 Other disorders of gallbladder Digestive 0.943 0.844 – 1.05 0.306 352 1862 exclusion phecode
575.8 Other disorders of biliary tract Digestive 1.01 0.909 – 1.13 0.812 390 2254 exclusion phecode
575.9
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of biliary tract
 Digestive 0.994 0.8 – 1.24 0.958 106 523 exclusion phecode
577 Diseases of pancreas Digestive 1.01 0.932 – 1.09 0.87 768 4855 exclusion phecode
577.1 Acute pancreatitis Digestive 0.967 0.875 – 1.07 0.52 433 2674 exclusion phecode
577.2 Chronic pancreatitis Digestive 0.921 0.79 – 1.07 0.29 196 1081 exclusion phecode
577.3 Cyst and pseudocyst of pancreas Digestive 1.06 0.91 – 1.24 0.451 206 1299 exclusion phecode
578 Gastrointestinal hemorrhage Digestive 0.989 0.939 – 1.04 0.687 1857 6346 exclusion phecode
578.1 Hematemesis Digestive 1.02 0.879 – 1.18 0.808 220 913 exclusion phecode
578.2 Blood in stool Digestive 1 0.937 – 1.07 0.989 1165 4716 exclusion phecode
578.8 Hemorrhage of rectum and anus Digestive 0.996 0.925 – 1.07 0.911 899 3838 exclusion phecode
578.9 Hemorrhage of gastrointestinal tract Digestive 1.04 0.958 – 1.13 0.338 727 2824 exclusion phecode
579 Other symptoms involving abdomen and pelvis Digestive 1.01 0.956 – 1.07 0.666 1494 5792 exclusion phecode
579.2 Splenomegaly Digestive 1.05 0.929 – 1.19 0.428 335 1347 exclusion phecode
579.8 Nonspecific abnormal findings in stool contents Digestive 0.96 0.879 – 1.05 0.357 639 2641 exclusion phecode
580 Nephritis; nephrosis; renal sclerosis Genitourinary 1.09 1.01 – 1.17 0.0198 1099 2676 exclusion phecode
580.1 Glomerulonephritis Genitourinary 1.13 0.972 – 1.32 0.111 236 728 exclusion phecode
580.11 Proliferative glomerulonephritis Genitourinary 1.2 0.928 – 1.55 0.166 79 262 exclusion phecode
580.12 Non-proliferative glomerulonephritis Genitourinary 1.3 0.962 – 1.77 0.087 64 208 exclusion phecode
580.13 Acute glomerulonephritis, NOS Genitourinary 1 0.691 – 1.46 0.983 38 117 exclusion phecode
580.14 Chronic glomerulonephritis, NOS Genitourinary 1.14 0.948 – 1.37 0.163 177 493 exclusion phecode
580.2
Nephrotic syndrome without mention of
Nephrotic syndrome without mention of glomerulonephritis
 Genitourinary 1.12 0.897 – 1.41 0.312 108 414 exclusion phecode
580.3
Nephritis and nephropathy without mention of
Nephritis and nephropathy without mention of glomerulonephritis
 Genitourinary 1.09 1.01 – 1.18 0.0261 953 2183 exclusion phecode
580.31
Nephritis and nephropathy in diseases
Nephritis and nephropathy in diseases classified elsewhere
 Genitourinary 1.07 0.983 – 1.18 0.114 723 1552 exclusion phecode
580.32
Nephritis and nephropathy with pathological
Nephritis and nephropathy with pathological lesion
 Genitourinary 1.14 1.02 – 1.29 0.0261 359 1276 exclusion phecode
580.4 Renal sclerosis, NOS Genitourinary 1.04 0.867 – 1.24 0.7 155 575 exclusion phecode
585 Renal failure Genitourinary 1.08 1.03 – 1.13 0.00191 2990 5042 exclusion phecode
585.1 Acute renal failure Genitourinary 1.09 1.03 – 1.15 0.00192 1961 4223 exclusion phecode
585.2 Renal failure NOS Genitourinary 1.07 0.963 – 1.19 0.206 459 1423 exclusion phecode
585.3 Chronic renal failure [CKD] Genitourinary 1.09 1.03 – 1.15 0.00207 2350 4621 exclusion phecode
585.31 Renal dialysis Genitourinary 1.11 0.992 – 1.24 0.0698 442 1294 exclusion phecode
585.32 End stage renal disease Genitourinary 1.1 1 – 1.21 0.0494 603 1693 exclusion phecode
585.33 Chronic Kidney Disease, Stage III Genitourinary 1.11 1.05 – 1.18 0.000653 1584 3459 exclusion phecode
585.34 Chronic Kidney Disease, Stage IV Genitourinary 1.09 0.983 – 1.2 0.106 549 1599 exclusion phecode
585.4 Chronic kidney disease, Stage I or II Genitourinary 1.1 1.01 – 1.21 0.0274 694 2009 exclusion phecode
586 Other disorders of the kidney and ureters Genitourinary 1.06 1.01 – 1.11 0.0181 2675 5308 exclusion phecode
586.1 Anatomical abnormatilies of kidney and ureters Genitourinary 1.07 0.876 – 1.3 0.523 120 566 exclusion phecode
586.11 Small kidney Genitourinary 1.12 0.871 – 1.44 0.378 75 385 exclusion phecode
586.12 Vesicoureteral reflux Genitourinary 0.756 0.532 – 1.07 0.118 42 196 exclusion phecode
586.2 Cyst of kidney, acquired Genitourinary 1.04 0.94 – 1.14 0.469 508 2087 exclusion phecode
586.3 Vascular disorders of kidney/hypertrophy Genitourinary 1.23 0.976 – 1.54 0.0801 104 329 exclusion phecode
586.4 Stricture/obstruction of ureter Genitourinary 1.03 0.936 – 1.14 0.523 477 2567 exclusion phecode
587 Kidney replaced by transpant Genitourinary 1.09 0.982 – 1.21 0.106 510 1394 exclusion phecode
588 Disorders resulting from impaired renal function Genitourinary 1.03 0.937 – 1.14 0.512 606 1691 exclusion phecode
588.1 Renal osteodystrophy Genitourinary 1.14 0.963 – 1.34 0.129 206 479 exclusion phecode
588.2 Secondary hyperparathyroidism (of renal origin) Genitourinary 1.04 0.932 – 1.16 0.495 465 1396 exclusion phecode
589 Abnormal results of function study of kidney Genitourinary 1.14 1.03 – 1.26 0.0127 529 1706 exclusion phecode
590 Pyelonephritis Genitourinary 1.03 0.936 – 1.13 0.572 567 2369 exclusion phecode
591 Urinary tract infection Genitourinary 1.02 0.971 – 1.06 0.472 3173 5400 exclusion phecode
592 Cystitis and urethritis Genitourinary 1.05 0.979 – 1.12 0.178 1076 3953 exclusion phecode
592.1 Cystitis Genitourinary 1.05 0.982 – 1.13 0.151 1031 3789 exclusion phecode
592.11 Acute cystitis Genitourinary 1.07 0.985 – 1.16 0.107 718 2693 exclusion phecode
592.12 Chronic cystitis Genitourinary 0.857 0.674 – 1.09 0.208 78 397 exclusion phecode
592.13 Chronic interstitial cystitis Genitourinary 1.08 0.866 – 1.34 0.506 88 623 exclusion phecode
592.2 Urethritis and urethral syndrome Genitourinary 1.06 0.805 – 1.39 0.681 69 384 exclusion phecode
593 Hematuria Genitourinary 1.04 0.98 – 1.09 0.219 1752 5321 exclusion phecode
593.1 Gross hematuria Genitourinary 0.975 0.89 – 1.07 0.584 582 2752 exclusion phecode
593.2 Microscopic hematuria Genitourinary 1.05 0.944 – 1.17 0.369 410 1779 exclusion phecode
594 Urinary calculus Genitourinary 0.998 0.947 – 1.05 0.936 1735 7443 exclusion phecode
594.1 Calculus of kidney Genitourinary 0.996 0.944 – 1.05 0.888 1643 7407 exclusion phecode
594.2 Calculus of lower urinary tract Genitourinary 1.16 0.955 – 1.42 0.132 107 810 exclusion phecode
594.3 Calculus of ureter Genitourinary 0.988 0.894 – 1.09 0.816 444 2740 exclusion phecode
594.8 Renal colic Genitourinary 1.14 0.922 – 1.41 0.225 109 694 exclusion phecode
595 Hydronephrosis Genitourinary 0.953 0.863 – 1.05 0.336 463 3189 exclusion phecode
596 Other disorders of bladder Genitourinary 1.02 0.954 – 1.1 0.502 889 5593 exclusion phecode
596.1 Bladder neck obstruction Genitourinary 0.905 0.733 – 1.12 0.351 102 867 exclusion phecode
596.5 Functional disorders of bladder Genitourinary 1.03 0.941 – 1.13 0.518 551 3469 exclusion phecode
597 Other disorders of urethra and urinary tract Genitourinary 1.1 0.97 – 1.25 0.136 271 2411 exclusion phecode
597.1 Urethral stricture (not specified as infectious) Genitourinary 1.07 0.898 – 1.27 0.457 140 1307 exclusion phecode
597.2 Urinary complications NEC Genitourinary 1.07 0.935 – 1.21 0.339 257 2127 exclusion phecode
597.8 Urethral hypermobility/ISD Genitourinary 0.931 0.653 – 1.33 0.693 34 365 exclusion phecode
598 Abnormal findings on examination of urine Genitourinary 1.07 0.789 – 1.46 0.653 51 315 exclusion phecode
598.4 Other cells and casts in urine Genitourinary 1.06 0.762 – 1.49 0.716 44 285 exclusion phecode
599 Other symptoms/disorders or the urinary system Genitourinary 1.01 0.965 – 1.05 0.739 4132 5084 exclusion phecode
599.1 Urinary obstruction Genitourinary 0.964 0.843 – 1.1 0.599 256 1263 exclusion phecode
599.2 Retention of urine Genitourinary 1 0.943 – 1.07 0.925 1445 4497 exclusion phecode
599.3 Dysuria Genitourinary 1 0.945 – 1.06 0.939 1547 4655 exclusion phecode
599.4 Urinary incontinence Genitourinary 0.976 0.92 – 1.04 0.433 1516 4465 exclusion phecode
599.5 Frequency of urination and polyuria Genitourinary 1.01 0.958 – 1.07 0.658 1816 4848 exclusion phecode
599.6 Oliguria and anuria Genitourinary 1.03 0.908 – 1.18 0.611 289 942 exclusion phecode
599.7 Urethral discharge Genitourinary 0.807 0.58 – 1.12 0.203 41 285 exclusion phecode
599.8 Other symptoms involving urinary system Genitourinary 1.05 0.988 – 1.11 0.116 1574 4642 exclusion phecode
599.9 Other abnormality of urination Genitourinary 0.972 0.906 – 1.04 0.418 983 4214 exclusion phecode
600 Hyperplasia of prostate Genitourinary 0.931 0.865 – 1 0.0525 1479 2300 exclusion phecode
601 Inflammatory diseases of prostate Genitourinary 0.936 0.84 – 1.04 0.226 403 2012 exclusion phecode
601.1 Prostatitis Genitourinary 0.933 0.796 – 1.09 0.39 184 1034 exclusion phecode
601.11 Acute prostatitis Genitourinary 1.02 0.74 – 1.41 0.896 45 270 exclusion phecode
601.12 Chronic prostatitis Genitourinary 1.12 0.76 – 1.66 0.559 33 217 exclusion phecode
601.3 Orchitis and epididymitis Genitourinary 0.943 0.786 – 1.13 0.532 150 773 exclusion phecode
601.4 Balanoposthitis Genitourinary 0.856 0.611 – 1.2 0.364 47 238 exclusion phecode
601.8
Other inflammatory disorders of male genital
Other inflammatory disorders of male genital organs
 Genitourinary 1.04 0.8 – 1.35 0.766 69 311 exclusion phecode
602 Other disorders of prostate Genitourinary 0.915 0.751 – 1.11 0.376 115 734 exclusion phecode
602.3 Dysplasia of prostate Genitourinary 0.869 0.566 – 1.34 0.522 22 174 exclusion phecode
603 Other disorders of testis Genitourinary 0.846 0.707 – 1.01 0.0673 157 784 exclusion phecode
603.1 Hydrocele Genitourinary 0.815 0.656 – 1.01 0.0656 115 552 exclusion phecode
603.2 Spermatocele Genitourinary 0.834 0.622 – 1.12 0.224 59 270 exclusion phecode
604 Disorders of penis Genitourinary 0.957 0.825 – 1.11 0.557 221 1181 exclusion phecode
604.1 Redundant prepuce and phimosis/BXO Genitourinary 1.26 0.924 – 1.73 0.142 52 279 exclusion phecode
604.3 Peyronie's disease Genitourinary 0.683 0.5 – 0.935 0.0173 47 361 exclusion phecode
605 Erectile dysfunction [ED] Genitourinary 0.95 0.884 – 1.02 0.161 1325 2135 exclusion phecode
608 Other disorders of male genital organs Genitourinary 0.911 0.83 – 0.999 0.0476 595 2271 exclusion phecode
609 Male infertility and abnormal spermatozoa Genitourinary 0.808 0.667 – 0.979 0.0294 133 796 exclusion phecode
609.1 Infertility, male Genitourinary 0.785 0.617 – 0.999 0.0493 92 539 exclusion phecode
609.11 Azoospermia and oligospermia Genitourinary 0.765 0.503 – 1.16 0.21 26 168 exclusion phecode
609.2 Abnormal spermatozoa Genitourinary 0.847 0.628 – 1.14 0.276 48 302 exclusion phecode
610 Benign mammary dysplasias Genitourinary 0.928 0.861 – 1 0.0485 1011 2371 exclusion phecode
610.1 Cystic mastopathy Genitourinary 0.895 0.809 – 0.99 0.0305 438 1978 exclusion phecode
610.2 Fibroadenosis of breast Genitourinary 0.862 0.534 – 1.39 0.543 25 90 exclusion phecode
610.4 Benign neoplasm of breast Genitourinary 0.949 0.875 – 1.03 0.213 778 2335 exclusion phecode
610.8 Other specified benign mammary dysplasias Genitourinary 0.9 0.8 – 1.01 0.0824 310 1661 exclusion phecode
611 Abnormal findings on mammogram or breast exam Genitourinary 0.928 0.874 – 0.985 0.0148 1907 2962 exclusion phecode
611.1 Abnormal mammogram Genitourinary 0.928 0.869 – 0.991 0.0266 1526 2367 exclusion phecode
611.11 Mammographic microcalcification Genitourinary 0.903 0.808 – 1.01 0.0719 381 1477 exclusion phecode
611.3 Lump or mass in breast Genitourinary 0.927 0.865 – 0.994 0.0331 1145 2935 exclusion phecode
612
Breast conditions, congenital or relating to
Breast conditions, congenital or relating to hormones
 Genitourinary 0.899 0.796 – 1.02 0.0868 307 1665 exclusion phecode
612.1 Galactorrhea Genitourinary 1.02 0.713 – 1.47 0.901 45 233 exclusion phecode
612.2 Hypertrophy of breast (Gynecomastia) Genitourinary 0.887 0.772 – 1.02 0.0892 226 1259 exclusion phecode
612.3 Congenital anomalies of breast Genitourinary 0.528 0.332 – 0.839 0.0069 30 124 exclusion phecode
613 Other nonmalignant breast conditions Genitourinary 0.956 0.895 – 1.02 0.184 1150 3967 exclusion phecode
613.1 Inflammatory disease of breast Genitourinary 0.973 0.823 – 1.15 0.753 163 1014 exclusion phecode
613.5 Mastodynia Genitourinary 0.922 0.842 – 1.01 0.0821 553 2939 exclusion phecode
613.7 Other signs and symptoms in breast Genitourinary 0.986 0.87 – 1.12 0.823 283 1583 exclusion phecode
613.8 Other specified disorders of breast Genitourinary 1.11 0.963 – 1.27 0.153 245 1580 exclusion phecode
613.9 Breast disorder NOS Genitourinary 0.932 0.838 – 1.04 0.188 394 2400 exclusion phecode
614 Inflammatory diseases of female pelvic organs Genitourinary 0.94 0.88 – 1.01 0.0707 1206 3285 exclusion phecode
614.1
Pelvic peritoneal adhesions, female
Pelvic peritoneal adhesions, female (postoperative) (postinfection)
 Genitourinary 0.946 0.738 – 1.21 0.663 81 534 exclusion phecode
614.3 Pelvic inflammatory disease (PID) Genitourinary 1.18 0.978 – 1.42 0.0832 145 768 exclusion phecode
614.31 Acute inflammatory pelvic disease Genitourinary 1.39 0.835 – 2.32 0.205 24 139 exclusion phecode
614.32 Chronic inflammatory pelvic disease Genitourinary 1.18 0.861 – 1.61 0.307 54 257 exclusion phecode
614.33 Pelvic inflammatory disease, NOS Genitourinary 1.33 1.03 – 1.73 0.0288 82 406 exclusion phecode
614.4 Inflammatory diseases of uterus, except cervix Genitourinary 1.12 0.834 – 1.5 0.452 56 291 exclusion phecode
614.5
Inflammatory disease of cervix, vagina, and
Inflammatory disease of cervix, vagina, and vulva
 Genitourinary 0.922 0.86 – 0.989 0.0229 1072 3257 exclusion phecode
614.51 Cervicitis and endocervicitis Genitourinary 0.869 0.694 – 1.09 0.222 83 476 exclusion phecode
614.52 Vaginitis and vulvovaginitis Genitourinary 0.92 0.855 – 0.991 0.0274 935 3148 exclusion phecode
614.53 Cyst or abscess of Bartholin's gland Genitourinary 1.08 0.767 – 1.53 0.654 45 266 exclusion phecode
614.54 Abscess or ulceration of vulva Genitourinary 1.04 0.82 – 1.33 0.724 73 423 exclusion phecode
615 Endometriosis Genitourinary 0.931 0.834 – 1.04 0.203 368 2372 exclusion phecode
618 Genital prolapse Genitourinary 0.971 0.882 – 1.07 0.548 459 3293 exclusion phecode
618.1 Prolapse of vaginal walls Genitourinary 0.93 0.823 – 1.05 0.244 275 2454 exclusion phecode
618.2 Uterine/Uterovaginal prolapse Genitourinary 0.967 0.803 – 1.16 0.72 122 970 exclusion phecode
618.5 Prolapse of vaginal vault after hysterectomy Genitourinary 1 0.728 – 1.38 0.991 38 538 exclusion phecode
618.6 Vaginal enterocele, congenital or acquired Genitourinary 1.06 0.87 – 1.29 0.566 108 769 exclusion phecode
619 Noninflammatory female genital disorders Genitourinary 0.95 0.894 – 1.01 0.0982 1639 3064 exclusion phecode
619.1
Noninflammatory disorders of ovary, fallopian
Noninflammatory disorders of ovary, fallopian tube, and broad ligament
 Genitourinary 0.866 0.77 – 0.974 0.0161 340 1890 exclusion phecode
619.2 Disorders of uterus, NEC Genitourinary 0.93 0.793 – 1.09 0.376 178 1004 exclusion phecode
619.3 Noninflammatory disorders of cervix Genitourinary 0.904 0.76 – 1.07 0.252 149 742 exclusion phecode
619.4 Noninflammatory disorders of vagina Genitourinary 0.969 0.895 – 1.05 0.43 811 2993 exclusion phecode
619.5 Noninflammatory disorders of vulva and perineum Genitourinary 1.02 0.916 – 1.13 0.725 384 2038 exclusion phecode
620 Dysplasia of female genital organs Genitourinary 0.996 0.814 – 1.22 0.965 115 694 exclusion phecode
620.1 Dysplasia of cervix Genitourinary 1.07 0.802 – 1.42 0.651 62 303 exclusion phecode
621 Endometrial hyperplasia Genitourinary 0.819 0.677 – 0.991 0.0396 131 671 exclusion phecode
622 Polyp of female genital organs Genitourinary 0.873 0.792 – 0.963 0.00684 466 2518 exclusion phecode
622.1 Polyp of corpus uteri Genitourinary 0.892 0.798 – 0.997 0.0446 360 1947 exclusion phecode
622.2 Mucous polyp of cervix Genitourinary 0.762 0.638 – 0.909 0.00256 150 783 exclusion phecode
623 Hypertrophy of female genital organs Genitourinary 0.965 0.856 – 1.09 0.566 292 1503 exclusion phecode
624 Symptoms involving female genital tract Genitourinary 0.951 0.858 – 1.05 0.34 450 1952 exclusion phecode
624.1 Dystrophy of female genital tract Genitourinary 0.916 0.704 – 1.19 0.51 66 378 exclusion phecode
624.2 Atrophy of female genital tract Genitourinary 1.2 0.763 – 1.9 0.424 18 133 exclusion phecode
624.9 stress incontinence, female Genitourinary 0.969 0.88 – 1.07 0.52 491 2341 exclusion phecode
625
Pain and other symptoms associated with female
Pain and other symptoms associated with female genital organs
 Genitourinary 0.918 0.863 – 0.977 0.00689 1662 2683 exclusion phecode
625.1 Dyspareunia Genitourinary 1.01 0.896 – 1.14 0.88 322 1786 exclusion phecode
626
Disorders of menstruation and other abnormal
Disorders of menstruation and other abnormal bleeding from female genital tract
 Genitourinary 0.915 0.857 – 0.977 0.00776 1836 2105 exclusion phecode
626.1 Irregular menstrual cycle/bleeding Genitourinary 0.913 0.851 – 0.98 0.0116 1477 1944 exclusion phecode
626.11 Absent or infrequent menstruation Genitourinary 0.945 0.841 – 1.06 0.342 378 1137 exclusion phecode
626.12 Excessive or frequent menstruation Genitourinary 0.876 0.801 – 0.958 0.00372 745 1543 exclusion phecode
626.13 Irregular menstrual cycle Genitourinary 0.917 0.838 – 1 0.061 697 1626 exclusion phecode
626.14 Irregular menstrual bleeding Genitourinary 0.908 0.807 – 1.02 0.109 364 1148 exclusion phecode
626.15 Infertility, female, associated with anovulation Genitourinary 1.08 0.902 – 1.29 0.408 156 591 exclusion phecode
626.2 Dysmenorrhea Genitourinary 0.972 0.869 – 1.09 0.615 437 1253 exclusion phecode
626.4 Premenstrual tension syndromes Genitourinary 0.906 0.742 – 1.11 0.336 121 469 exclusion phecode
626.8 Infertility, female Genitourinary 1.07 0.933 – 1.22 0.346 285 885 exclusion phecode
627 Menopausal and postmenopausal disorders Genitourinary 0.838 0.782 – 0.898 6.61e-07 1348 1938 exclusion phecode
627.1 Postmenopausal bleeding Genitourinary 0.829 0.739 – 0.931 0.00152 334 1413 exclusion phecode
627.2 Symptomatic menopause Genitourinary 0.854 0.789 – 0.926 0.000115 896 1823 exclusion phecode
627.21 Symptomatic artificial menopause Genitourinary 0.815 0.614 – 1.08 0.155 54 199 exclusion phecode
627.22
Need for Hormone replacement therapy
Need for Hormone replacement therapy (postmenopausal)
 Genitourinary 0.957 0.779 – 1.18 0.674 98 564 exclusion phecode
627.3 Postmenopausal atrophic vaginitis Genitourinary 0.869 0.768 – 0.982 0.0245 303 1325 exclusion phecode
627.4 Premenopausal menorrhagia Genitourinary 0.949 0.79 – 1.14 0.571 131 505 exclusion phecode
627.5 Premature menopause and other ovarian failure Genitourinary 0.787 0.636 – 0.973 0.0268 96 428 exclusion phecode
628 Ovarian cyst Genitourinary 0.896 0.817 – 0.984 0.0211 606 1825 exclusion phecode
634 Miscarriage; stillbirth Pregnancy Complications 1.09 0.96 – 1.25 0.176 280 1469 exclusion phecode
634.1 Missed abortion/Hydatidiform mole Pregnancy Complications 1.03 0.821 – 1.28 0.825 99 550 exclusion phecode
634.3 Ectopic pregnancy Pregnancy Complications 1.08 0.759 – 1.55 0.655 36 215 exclusion phecode
635
Hemorrhage during pregnancy; childbirth and
Hemorrhage during pregnancy; childbirth and postpartum
 Pregnancy Complications 1.17 1 – 1.36 0.0491 199 1002 exclusion phecode
635.2
Antepartum hemorrhage, abruptio placentae, and
Antepartum hemorrhage, abruptio placentae, and placenta previa
 Pregnancy Complications 1.2 0.991 – 1.44 0.0621 141 691 exclusion phecode
635.3 Placenta previa and abruptio placenta Pregnancy Complications 1.09 0.875 – 1.36 0.444 94 550 exclusion phecode
636
Early or threatened labor; hemorrhage in early
Early or threatened labor; hemorrhage in early pregnancy
 Pregnancy Complications 1.05 0.936 – 1.18 0.391 378 1470 exclusion phecode
636.1 Threatened premature labor Pregnancy Complications 1.05 0.869 – 1.27 0.603 139 682 exclusion phecode
636.2 Early onset of delivery Pregnancy Complications 0.955 0.777 – 1.17 0.664 119 552 exclusion phecode
636.3 Hemorrhage in early pregnancy Pregnancy Complications 1.19 1 – 1.42 0.0489 165 825 exclusion phecode
636.8 Cervical incompetence Pregnancy Complications 1.01 0.608 – 1.66 0.984 24 154 exclusion phecode
637
Short gestation; low birth weight; and fetal
Short gestation; low birth weight; and fetal growth retardation
 Pregnancy Complications 1.2 0.812 – 1.78 0.357 33 159 exclusion phecode
642
Hypertension complicating pregnancy
Hypertension complicating pregnancy, childbirth, and the puerperium
 Pregnancy Complications 1.15 0.974 – 1.35 0.101 193 1228 exclusion phecode
642.1 Preeclampsia and eclampsia Pregnancy Complications 1.14 0.918 – 1.42 0.233 109 682 exclusion phecode
643 Excessive vomiting in pregnancy Pregnancy Complications 1 0.802 – 1.25 0.997 91 560 exclusion phecode
643.1 Hyperemesis gravidarum Pregnancy Complications 1.06 0.743 – 1.5 0.761 43 257 exclusion phecode
644 Anemia during pregnancy Pregnancy Complications 0.921 0.727 – 1.17 0.492 80 512 exclusion phecode
646 Other complications of pregnancy NEC Pregnancy Complications 1.05 0.919 – 1.21 0.453 269 1266 exclusion phecode
647
Infectious and parasitic complications
Infectious and parasitic complications affecting pregnancy
 Pregnancy Complications 1.01 0.784 – 1.31 0.921 72 488 exclusion phecode
647.1
Infections of genitourinary tract during
Infections of genitourinary tract during pregnancy
 Pregnancy Complications 0.981 0.762 – 1.26 0.881 78 464 exclusion phecode
647.3 Major puerperal infection Pregnancy Complications 0.927 0.57 – 1.51 0.761 18 151 exclusion phecode
649
Other conditions or status of the mother
Other conditions or status of the mother complicating pregnancy, childbirth, or the puerperium
 Pregnancy Complications 1.06 0.948 – 1.19 0.302 424 1499 exclusion phecode
649.1
Diabetes or abnormal glucose tolerance
Diabetes or abnormal glucose tolerance complicating pregnancy
 Pregnancy Complications 1.03 0.901 – 1.18 0.662 263 1303 exclusion phecode
653
Problems associated with amniotic cavity and
Problems associated with amniotic cavity and membranes
 Pregnancy Complications 1.02 0.871 – 1.18 0.841 199 1105 exclusion phecode
654.1
Abnormality of organs and soft tissues of
Abnormality of organs and soft tissues of pelvis complicating pregnancy, childbirth, or the puerperium
 Pregnancy Complications 1.14 0.87 – 1.48 0.349 70 402 exclusion phecode
654.2 Rhesus isoimmunization in pregnancy Pregnancy Complications 1.13 0.864 – 1.47 0.373 76 410 exclusion phecode
655
Known or suspected fetal abnormality affecting
Known or suspected fetal abnormality affecting management of mother
 Pregnancy Complications 1.05 0.955 – 1.16 0.298 547 1875 exclusion phecode
655.1 Abnormality in fetal heart rate or rhythm Pregnancy Complications 1.08 0.932 – 1.26 0.299 225 1051 exclusion phecode
656 Other perinatal conditions of fetus or newborn Pregnancy Complications 1.09 0.96 – 1.24 0.178 300 1362 exclusion phecode
656.2 Respiratory conditions of fetus and newborn Pregnancy Complications 0.998 0.632 – 1.58 0.993 24 143 exclusion phecode
669 Complications of labor and delivery NEC Pregnancy Complications 1.08 0.948 – 1.23 0.249 304 1347 exclusion phecode
671
Venous/cerebrovascular complications embolism
Venous/cerebrovascular complications embolism in pregnancy and the puerperium
 Pregnancy Complications 0.998 0.769 – 1.3 0.988 72 445 exclusion phecode
674 Other complications of the puerperium NEC Pregnancy Complications 0.993 0.737 – 1.34 0.962 49 343 exclusion phecode
676
Other disorders of the breast associated with
Other disorders of the breast associated with childbirth and disorders of lactation
 Pregnancy Complications 0.986 0.76 – 1.28 0.913 83 404 exclusion phecode
681 Superficial cellulitis and abscess Dermatologic 0.98 0.935 – 1.03 0.403 2423 6666 exclusion phecode
681.1 Cellulitis and abscess of fingers/toes Dermatologic 1 0.918 – 1.09 0.982 637 2566 exclusion phecode
681.2 Cellulitis and abscess of face/neck Dermatologic 1.05 0.932 – 1.18 0.432 343 1895 exclusion phecode
681.3 Cellulitis and abscess of arm/hand Dermatologic 0.994 0.926 – 1.07 0.873 969 3791 exclusion phecode
681.5 Cellulitis and abscess of leg, except foot Dermatologic 1.01 0.94 – 1.08 0.869 1048 3951 exclusion phecode
681.6 Cellulitis and abscess of foot, toe Dermatologic 1.03 0.953 – 1.11 0.477 867 3321 exclusion phecode
681.7 Cellulitis and abscess of trunk Dermatologic 0.952 0.872 – 1.04 0.272 584 2935 exclusion phecode
686
Other local infections of skin and subcutaneous
Other local infections of skin and subcutaneous tissue
 Dermatologic 1.02 0.946 – 1.1 0.622 872 4006 exclusion phecode
686.1 Carbuncle and furuncle Dermatologic 1.01 0.872 – 1.17 0.908 226 1160 exclusion phecode
686.2 Impetigo Dermatologic 0.97 0.816 – 1.15 0.727 165 827 exclusion phecode
686.3 Pilonidal cyst Dermatologic 1 0.751 – 1.34 0.975 55 366 exclusion phecode
686.4 Pyogenic granuloma Dermatologic 0.854 0.622 – 1.17 0.33 49 270 exclusion phecode
686.5 Pyoderma Dermatologic 1.11 0.738 – 1.67 0.617 25 132 exclusion phecode
687 Symptoms affecting skin Dermatologic 0.93 0.856 – 1.01 0.0879 683 2902 exclusion phecode
687.1 Rash and other nonspecific skin eruption Dermatologic 0.94 0.897 – 0.985 0.0093 2662 5505 exclusion phecode
687.3 Changes in skin texture Dermatologic 0.939 0.806 – 1.09 0.422 194 947 exclusion phecode
687.4 Disturbance of skin sensation Dermatologic 0.927 0.881 – 0.975 0.00318 2143 5453 exclusion phecode
689 Disorder of skin and subcutaneous tissue NOS Dermatologic 0.978 0.936 – 1.02 0.301 3310 6350 exclusion phecode
690 Erythematosquamous dermatosis Dermatologic 0.926 0.879 – 0.974 0.00313 2038 5496 exclusion phecode
690.1 Seborrheic dermatitis Dermatologic 0.926 0.88 – 0.975 0.00325 2037 5491 exclusion phecode
691 Congenital anomalies of skin Dermatologic 0.887 0.764 – 1.03 0.114 204 972 exclusion phecode
691.3 Congenital pigmentary anomalies of skin Dermatologic 1.04 0.609 – 1.78 0.88 14 99 exclusion phecode
694 Dyschromia and Vitiligo Dermatologic 0.907 0.835 – 0.986 0.0216 661 3213 exclusion phecode
694.1 Vitiligo Dermatologic 1.02 0.783 – 1.34 0.865 54 313 exclusion phecode
694.2 Other dyschromia Dermatologic 0.879 0.804 – 0.961 0.00452 579 2868 exclusion phecode
694.3 Vascular disorders of skin Dermatologic 1.31 0.897 – 1.9 0.164 40 136 exclusion phecode
695 Erythematous conditions Dermatologic 0.908 0.857 – 0.963 0.00119 1480 5252 exclusion phecode
695.1 Toxic erythema Dermatologic 0.763 0.518 – 1.12 0.17 25 144 exclusion phecode
695.2 Bullous dermatoses Dermatologic 1.03 0.667 – 1.6 0.882 32 141 exclusion phecode
695.3 Rosacea Dermatologic 0.892 0.82 – 0.97 0.00744 643 3142 exclusion phecode
695.4 Lupus (localized and systemic) Dermatologic 1 0.86 – 1.16 0.998 210 1010 exclusion phecode
695.41 Cutaneous lupus erythematosus Dermatologic 1.01 0.802 – 1.28 0.913 89 362 exclusion phecode
695.42 Systemic lupus erythematosus Dermatologic 0.981 0.839 – 1.15 0.81 195 960 exclusion phecode
695.7 Prurigo and Lichen Dermatologic 0.872 0.754 – 1.01 0.0672 210 1113 exclusion phecode
695.8 Other specified erythematous conditions Dermatologic 0.937 0.837 – 1.05 0.264 358 1531 exclusion phecode
695.81 Erythema nodosum Dermatologic 0.643 0.386 – 1.07 0.0901 23 82 exclusion phecode
695.9 Unspecified erythematous condition Dermatologic 0.947 0.83 – 1.08 0.415 266 1310 exclusion phecode
696 Psoriasis and related disorders Dermatologic 0.921 0.832 – 1.02 0.114 432 2464 exclusion phecode
696.3 Pityriasis Dermatologic 0.939 0.644 – 1.37 0.742 28 151 exclusion phecode
696.4 Psoriasis Dermatologic 0.92 0.828 – 1.02 0.121 404 2354 exclusion phecode
696.41 Psoriasis vulgaris Dermatologic 0.919 0.824 – 1.02 0.129 383 2180 exclusion phecode
696.42 Psoriatic arthropathy Dermatologic 1.07 0.858 – 1.32 0.566 90 499 exclusion phecode
697 Sarcoidosis Dermatologic 0.919 0.745 – 1.13 0.432 95 618 exclusion phecode
698 Pruritus and related conditions Dermatologic 1.03 0.957 – 1.11 0.43 859 4437 exclusion phecode
700 Corns and callosities Dermatologic 1.01 0.929 – 1.09 0.849 798 2369 exclusion phecode
701
Other hypertrophic and atrophic conditions of
Other hypertrophic and atrophic conditions of skin
 Dermatologic 0.982 0.938 – 1.03 0.453 2543 6601 exclusion phecode
701.1 Keratoderma, acquired Dermatologic 0.981 0.851 – 1.13 0.786 246 1144 exclusion phecode
701.2 Scar conditions and fibrosis of skin Dermatologic 0.94 0.859 – 1.03 0.177 522 3590 exclusion phecode
701.3 Circumscribed scleroderma Dermatologic 0.982 0.836 – 1.15 0.82 168 970 exclusion phecode
701.4 Keloid scar Dermatologic 1.08 0.915 – 1.27 0.364 166 1007 exclusion phecode
701.5 Abnormal granulation tissue Dermatologic 0.897 0.736 – 1.09 0.281 120 729 exclusion phecode
702
Degenerative skin conditions and other
Degenerative skin conditions and other dermatoses
 Dermatologic 0.959 0.913 – 1.01 0.101 2633 4726 exclusion phecode
702.1 Actinic keratosis Dermatologic 0.953 0.9 – 1.01 0.105 1653 4703 exclusion phecode
702.2 Seborrheic keratosis Dermatologic 0.952 0.905 – 1 0.0615 2123 5690 exclusion phecode
702.4 Degenerative skin disorders Dermatologic 1.25 0.889 – 1.75 0.2 32 188 exclusion phecode
703 Diseases of nail, NOS Dermatologic 1.02 0.946 – 1.1 0.599 823 3258 exclusion phecode
703.1 Ingrowing nail Dermatologic 0.96 0.868 – 1.06 0.423 459 2072 exclusion phecode
704 Diseases of hair and hair follicles Dermatologic 0.965 0.905 – 1.03 0.267 1140 5585 exclusion phecode
704.1 Alopecia Dermatologic 0.954 0.864 – 1.05 0.356 466 2499 exclusion phecode
704.11 Alopecia Areata Dermatologic 1.03 0.709 – 1.51 0.859 31 165 exclusion phecode
704.12 Telogen effluvium Dermatologic 0.634 0.381 – 1.06 0.0807 24 89 exclusion phecode
704.2 Hirsutism Dermatologic 0.967 0.78 – 1.2 0.758 102 570 exclusion phecode
704.8
Other specified diseases of hair and hair
Other specified diseases of hair and hair follicles
 Dermatologic 0.996 0.918 – 1.08 0.925 699 3629 exclusion phecode
705 Disorders of sweat glands Dermatologic 1 0.859 – 1.17 0.988 218 1118 exclusion phecode
705.1 Dyshidrosis Dermatologic 0.939 0.718 – 1.23 0.646 65 290 exclusion phecode
705.3 Hidradenitis Dermatologic 1.04 0.808 – 1.34 0.754 79 423 exclusion phecode
705.8 Hyperhidrosis Dermatologic 1.01 0.907 – 1.12 0.89 450 2123 exclusion phecode
706 Diseases of sebaceous glands Dermatologic 0.953 0.909 – 0.999 0.0464 2355 6941 exclusion phecode
706.1 Acne Dermatologic 0.963 0.895 – 1.04 0.308 956 4030 exclusion phecode
706.2 Sebaceous cyst Dermatologic 0.955 0.895 – 1.02 0.174 1086 4960 exclusion phecode
706.3 Seborrhea Dermatologic 1.26 0.805 – 1.98 0.309 28 121 exclusion phecode
706.8 Other specified diseases of sebaceous glands Dermatologic 0.926 0.858 – 1 0.0507 783 3173 exclusion phecode
707 Chronic ulcer of skin Dermatologic 1.02 0.961 – 1.09 0.476 1181 5443 exclusion phecode
707.1 Decubitus ulcer Dermatologic 1.03 0.917 – 1.16 0.622 362 1773 exclusion phecode
707.2 Chronic ulcer of leg or foot Dermatologic 1.02 0.937 – 1.12 0.595 624 2446 exclusion phecode
707.3 Chronic ulcer of unspecified site Dermatologic 1.02 0.933 – 1.11 0.712 605 3452 exclusion phecode
709 Diffuse diseases of connective tissue Dermatologic 1.03 0.936 – 1.14 0.53 499 2493 exclusion phecode
709.2 Sicca syndrome Dermatologic 1.03 0.876 – 1.22 0.698 164 801 exclusion phecode
709.3 Systemic sclerosis Dermatologic 0.965 0.766 – 1.22 0.766 81 360 exclusion phecode
709.5 Dermatomyositis Dermatologic 1.12 0.772 – 1.64 0.541 34 173 exclusion phecode
709.6
Other specified diffuse diseases of connective
Other specified diffuse diseases of connective tissue
 Dermatologic 0.747 0.51 – 1.09 0.134 34 111 exclusion phecode
709.7 Unspecified diffuse connective tissue disease Dermatologic 1.06 0.939 – 1.2 0.349 321 1627 exclusion phecode
710
Osteomyelitis, periostitis, and other
Osteomyelitis, periostitis, and other infections involving bone
 Musculoskeletal 0.997 0.902 – 1.1 0.952 464 2238 exclusion phecode
710.1 Osteomyelitis Musculoskeletal 1.01 0.912 – 1.12 0.85 453 2162 exclusion phecode
710.11 Acute osteomyelitis Musculoskeletal 1.02 0.894 – 1.17 0.752 274 1196 exclusion phecode
710.12 Chronic osteomyelitis Musculoskeletal 0.978 0.849 – 1.13 0.754 218 1083 exclusion phecode
710.19 Unspecified osteomyelitis Musculoskeletal 1.01 0.906 – 1.12 0.917 430 2084 exclusion phecode
711 Arthropathy associated with infections Musculoskeletal 0.859 0.719 – 1.03 0.0943 153 707 exclusion phecode
711.1 Pyogenic arthritis Musculoskeletal 0.907 0.739 – 1.11 0.352 113 515 exclusion phecode
712 Infective connective tissue disorders Musculoskeletal 1.04 0.822 – 1.31 0.749 79 309 exclusion phecode
713
Arthropathy associated with other disorders
Arthropathy associated with other disorders classified elsewhere
 Musculoskeletal 1.06 0.893 – 1.25 0.522 175 827 exclusion phecode
713.5
Arthropathy associated with neurological
Arthropathy associated with neurological disorders
 Musculoskeletal 1.07 0.881 – 1.29 0.515 133 621 exclusion phecode
714
Rheumatoid arthritis and other inflammatory
Rheumatoid arthritis and other inflammatory polyarthropathies
 Musculoskeletal 0.999 0.917 – 1.09 0.975 652 3231 exclusion phecode
714.1 Rheumatoid arthritis Musculoskeletal 1 0.908 – 1.1 0.988 492 2594 exclusion phecode
714.2 Juvenile rheumatoid arthritis Musculoskeletal 1.15 0.732 – 1.8 0.55 23 166 exclusion phecode
715 Other inflammatory spondylopathies Musculoskeletal 0.931 0.838 – 1.04 0.188 423 2084 exclusion phecode
715.1 Sacroiliitis NEC Musculoskeletal 1.02 0.82 – 1.27 0.859 94 448 exclusion phecode
715.2 Ankylosing spondylitis Musculoskeletal 0.813 0.616 – 1.07 0.146 51 378 exclusion phecode
716 Other arthropathies Musculoskeletal 0.953 0.911 – 0.996 0.0336 3704 5406 exclusion phecode
716.1 Unspecified polyarthropathy or polyarthritis Musculoskeletal 0.847 0.661 – 1.08 0.188 76 348 exclusion phecode
716.2 Unspecified monoarthritis Musculoskeletal 0.78 0.581 – 1.05 0.0989 44 207 exclusion phecode
716.9 Arthropathy NOS Musculoskeletal 0.952 0.91 – 0.996 0.0336 3674 5405 exclusion phecode
717 Polymyalgia Rheumatica Musculoskeletal 1.1 0.878 – 1.37 0.415 90 653 exclusion phecode
720 Spinal stenosis Musculoskeletal 0.936 0.878 – 0.998 0.0416 1244 4947 exclusion phecode
720.1 Spinal stenosis of lumbar region Musculoskeletal 0.915 0.852 – 0.983 0.0152 965 4132 exclusion phecode
721 Spondylosis and allied disorders Musculoskeletal 0.948 0.899 – 1 0.0497 1895 5752 exclusion phecode
721.1 Spondylosis without myelopathy Musculoskeletal 0.942 0.892 – 0.994 0.0297 1801 5681 exclusion phecode
721.2 Spondylosis with myelopathy Musculoskeletal 0.936 0.818 – 1.07 0.332 248 1513 exclusion phecode
721.8 Other allied disorders of spine Musculoskeletal 0.833 0.669 – 1.04 0.102 100 534 exclusion phecode
722 Intervertebral disc disorders Musculoskeletal 0.936 0.887 – 0.986 0.0133 1910 6009 exclusion phecode
722.1 Displacement of intervertebral disc Musculoskeletal 0.948 0.888 – 1.01 0.115 1084 5472 exclusion phecode
722.3 Schmorl's nodes Musculoskeletal 0.755 0.526 – 1.08 0.129 48 184 exclusion phecode
722.6 Degeneration of intervertebral disc Musculoskeletal 0.928 0.873 – 0.987 0.0172 1309 5423 exclusion phecode
722.7 Intervertebral disc disorder with myelopathy Musculoskeletal 0.99 0.823 – 1.19 0.914 133 829 exclusion phecode
722.8 Postlaminectomy syndrome Musculoskeletal 1.24 1.02 – 1.52 0.0337 112 731 exclusion phecode
722.9 Other and unspecified disc disorder Musculoskeletal 0.926 0.847 – 1.01 0.0876 561 3499 exclusion phecode
723 Other disorders of cervical region Musculoskeletal 0.959 0.848 – 1.09 0.508 309 1688 exclusion phecode
723.1 Torticollis Musculoskeletal 0.978 0.772 – 1.24 0.855 80 450 exclusion phecode
724 Other and unspecified disorders of back Musculoskeletal 0.932 0.878 – 0.989 0.021 1373 5691 exclusion phecode
724.1 Disorders of sacrum Musculoskeletal 0.928 0.861 – 1 0.0504 820 3945 exclusion phecode
724.2 Disorders of coccyx Musculoskeletal 0.843 0.713 – 0.996 0.0452 173 792 exclusion phecode
724.8 Other symptoms referable to back Musculoskeletal 0.881 0.783 – 0.992 0.036 334 1677 exclusion phecode
724.9 Other unspecified back disorders Musculoskeletal 0.988 0.89 – 1.1 0.814 397 2387 exclusion phecode
726 Peripheral enthesopathies and allied syndromes Musculoskeletal 0.922 0.881 – 0.966 0.000568 3469 4264 exclusion phecode
726.1 Enthesopathy Musculoskeletal 0.916 0.871 – 0.963 0.000588 2574 4247 exclusion phecode
726.2 Synoviopathy Musculoskeletal 0.873 0.779 – 0.979 0.0201 361 1468 exclusion phecode
726.3 Bursitis Musculoskeletal 0.912 0.841 – 0.988 0.0245 753 2501 exclusion phecode
726.4 Calcaneal spur; Exostosis NOS Musculoskeletal 0.926 0.832 – 1.03 0.155 421 1729 exclusion phecode
727 Other disorders of synovium, tendon, and bursa Musculoskeletal 0.917 0.872 – 0.964 0.000743 2554 4242 exclusion phecode
727.1 Synovitis and tenosynovitis Musculoskeletal 0.927 0.867 – 0.992 0.0281 1146 3539 exclusion phecode
727.2 Bursitis disorders Musculoskeletal 0.917 0.765 – 1.1 0.351 157 632 exclusion phecode
727.4 Ganglion and cyst of synovium, tendon, and bursa Musculoskeletal 0.914 0.83 – 1.01 0.0674 498 2040 exclusion phecode
727.5 Rupture of synovium Musculoskeletal 0.819 0.688 – 0.976 0.0253 153 652 exclusion phecode
727.6 Rupture of tendon, nontraumatic Musculoskeletal 0.885 0.82 – 0.954 0.0015 872 3042 exclusion phecode
727.7 Contracture of tendon (sheath) Musculoskeletal 0.898 0.757 – 1.07 0.221 156 846 exclusion phecode
727.8 Plica syndrome Musculoskeletal 1.16 0.767 – 1.75 0.484 35 147 exclusion phecode
728 Disorders of muscle, ligament, and fascia Musculoskeletal 0.949 0.894 – 1.01 0.081 1559 4115 exclusion phecode
728.1 Muscular calcification and ossification Musculoskeletal 1 0.644 – 1.55 1 27 132 exclusion phecode
728.2 Laxity of ligament or hypermobility syndrome Musculoskeletal 0.928 0.742 – 1.16 0.509 100 409 exclusion phecode
728.7 Fasciitis Musculoskeletal 0.941 0.88 – 1.01 0.0748 1095 3372 exclusion phecode
728.71
Contracture of palmar fascia [Dupuytren's
Contracture of palmar fascia [Dupuytren's disease]
 Musculoskeletal 0.96 0.82 – 1.12 0.616 171 765 exclusion phecode
729 Other disorders of soft tissues Musculoskeletal 0.983 0.922 – 1.05 0.584 1390 3823 exclusion phecode
729.1 Rheumatism, unspecified and fibrositis Musculoskeletal 0.883 0.599 – 1.3 0.529 30 116 exclusion phecode
729.3 Panniculitis Musculoskeletal 1.36 0.932 – 1.98 0.111 43 170 exclusion phecode
729.7 Nontraumatic compartment syndrome Musculoskeletal 0.622 0.391 – 0.991 0.0457 19 100 exclusion phecode
731
Osteitis deformans and osteopathies associated
Osteitis deformans and osteopathies associated with other disorders classified elsewhere
 Musculoskeletal 0.967 0.78 – 1.2 0.761 118 540 exclusion phecode
732 Osteochondropathies Musculoskeletal 1.02 0.816 – 1.27 0.881 93 587 exclusion phecode
732.1 Juvenile osteochondrosis Musculoskeletal 1.01 0.763 – 1.34 0.936 58 359 exclusion phecode
732.7 Osteochondritis dissecans Musculoskeletal 1.04 0.68 – 1.58 0.864 28 131 exclusion phecode
733 Other disorders of bone and cartilage Musculoskeletal 0.978 0.921 – 1.04 0.457 1511 4778 exclusion phecode
733.2 Cyst of bone Musculoskeletal 1.16 0.841 – 1.6 0.369 46 321 exclusion phecode
733.4 Aseptic necrosis of bone Musculoskeletal 0.911 0.755 – 1.1 0.33 124 847 exclusion phecode
733.6 Costochondritis Musculoskeletal 1.06 0.862 – 1.3 0.596 118 625 exclusion phecode
733.8 Malunion and nonunion of fracture Musculoskeletal 0.942 0.805 – 1.1 0.455 163 1288 exclusion phecode
733.9 Chondromalacia Musculoskeletal 1.15 0.717 – 1.84 0.563 16 133 exclusion phecode
735 Acquired foot deformities Musculoskeletal 0.991 0.934 – 1.05 0.778 1362 5729 exclusion phecode
735.1 Flat foot Musculoskeletal 1.14 0.995 – 1.31 0.0596 257 1319 exclusion phecode
735.2 Acquired toe deformities Musculoskeletal 0.99 0.907 – 1.08 0.823 617 2701 exclusion phecode
735.21 Hammer toe (acquired) Musculoskeletal 0.963 0.867 – 1.07 0.481 433 1891 exclusion phecode
735.23 Hallux rigidus Musculoskeletal 0.952 0.796 – 1.14 0.594 134 818 exclusion phecode
735.3 Hallux valgus (Bunion) Musculoskeletal 0.898 0.82 – 0.983 0.0198 556 2948 exclusion phecode
736 Other acquired deformities of limbs Musculoskeletal 0.985 0.918 – 1.06 0.667 941 5091 exclusion phecode
736.1 Acquired deformities of forearm Musculoskeletal 0.674 0.433 – 1.05 0.0809 31 163 exclusion phecode
736.2 Acquired deformities of finger Musculoskeletal 1.03 0.794 – 1.33 0.833 71 415 exclusion phecode
736.3 Acquired deformities of hip Musculoskeletal 1.34 0.74 – 2.42 0.335 15 89 exclusion phecode
736.4 Genu valgum or varum (acquired) Musculoskeletal 0.886 0.712 – 1.1 0.277 93 559 exclusion phecode
736.5 Acquired deformities of knee Musculoskeletal 0.843 0.66 – 1.08 0.169 70 446 exclusion phecode
736.6 Unequal leg length (acquired) Musculoskeletal 0.978 0.799 – 1.2 0.826 110 592 exclusion phecode
737 Curvature of spine Musculoskeletal 0.927 0.838 – 1.03 0.141 439 2706 exclusion phecode
737.1 Kyphosis (acquired) Musculoskeletal 0.933 0.772 – 1.13 0.473 128 819 exclusion phecode
737.2 Lordosis (acquired) Musculoskeletal 0.954 0.583 – 1.56 0.85 17 120 exclusion phecode
737.3 Kyphoscoliosis and scoliosis Musculoskeletal 0.916 0.818 – 1.03 0.133 339 2030 exclusion phecode
738 Other acquired musculoskeletal deformity Musculoskeletal 0.988 0.905 – 1.08 0.78 574 4223 exclusion phecode
738.4 Acquired spondylolisthesis Musculoskeletal 0.991 0.875 – 1.12 0.89 291 1879 exclusion phecode
739 Contracture of joint Musculoskeletal 0.805 0.689 – 0.941 0.00635 185 1187 exclusion phecode
740 Osteoarthrosis Musculoskeletal 0.949 0.908 – 0.992 0.0198 4442 5120 exclusion phecode
740.1 Osteoarthritis; localized Musculoskeletal 0.932 0.883 – 0.983 0.00943 2371 4554 exclusion phecode
740.11 Osteoarthrosis, localized, primary Musculoskeletal 0.923 0.873 – 0.975 0.00426 2111 4391 exclusion phecode
740.12 Osteoarthrosis, localized, secondary Musculoskeletal 0.936 0.809 – 1.08 0.376 217 1170 exclusion phecode
740.2 Osteoarthrosis, generalized Musculoskeletal 0.94 0.857 – 1.03 0.187 659 2000 exclusion phecode
740.3
Osteoarthrosis involving more than one site
Osteoarthrosis involving more than one site, but not specified as generalized
 Musculoskeletal 0.892 0.741 – 1.07 0.227 150 524 exclusion phecode
740.9 Osteoarthrosis NOS Musculoskeletal 0.952 0.911 – 0.995 0.0309 4266 5093 exclusion phecode
741 Symptoms and disorders of the joints Musculoskeletal 0.979 0.936 – 1.03 0.373 2781 6258 exclusion phecode
741.1 Ankylosis of joint Musculoskeletal 0.987 0.735 – 1.32 0.93 49 373 exclusion phecode
741.2 Stiffness of joint Musculoskeletal 1.02 0.915 – 1.15 0.683 362 2225 exclusion phecode
741.3 Difficulty in walking Musculoskeletal 0.963 0.897 – 1.03 0.291 964 4068 exclusion phecode
741.4 Joint effusions Musculoskeletal 1.02 0.954 – 1.1 0.518 983 4207 exclusion phecode
741.5 Hemarthrosis Musculoskeletal 1.08 0.769 – 1.51 0.665 46 189 exclusion phecode
741.6 Villonodular synovitis Musculoskeletal 0.873 0.512 – 1.49 0.616 22 113 exclusion phecode
742 Derangement of joint, non-traumatic Musculoskeletal 0.936 0.882 – 0.994 0.0321 1349 5821 exclusion phecode
742.1 Loose body in joint Musculoskeletal 1.04 0.722 – 1.49 0.839 35 227 exclusion phecode
742.2
Pathological, developmental or recurrent
Pathological, developmental or recurrent dislocation
 Musculoskeletal 1 0.757 – 1.32 0.998 60 393 exclusion phecode
742.8 Articular cartilage disorder Musculoskeletal 0.918 0.712 – 1.18 0.509 61 379 exclusion phecode
742.9 Other derangement of joint Musculoskeletal 0.937 0.881 – 0.996 0.0375 1273 5663 exclusion phecode
743
Osteoporosis, osteopenia and pathological
Osteoporosis, osteopenia and pathological fracture
 Musculoskeletal 0.99 0.945 – 1.04 0.675 2821 6655 exclusion phecode
743.1 Osteoporosis Musculoskeletal 1.01 0.941 – 1.08 0.781 1122 3538 exclusion phecode
743.11 Osteoporosis NOS Musculoskeletal 1 0.935 – 1.08 0.909 1103 3501 exclusion phecode
743.12 Senile osteoporosis Musculoskeletal 0.914 0.793 – 1.05 0.211 252 850 exclusion phecode
743.13 Other specified osteoporosis Musculoskeletal 0.999 0.816 – 1.22 0.996 120 521 exclusion phecode
743.2 Pathologic fracture Musculoskeletal 1.01 0.901 – 1.13 0.873 360 1770 exclusion phecode
743.21 Pathologic fracture of vertebrae Musculoskeletal 1.05 0.881 – 1.25 0.595 156 782 exclusion phecode
743.22 Pathologic fracture of femur Musculoskeletal 1.31 0.914 – 1.88 0.141 41 220 exclusion phecode
743.4 Stress fracture Musculoskeletal 0.951 0.807 – 1.12 0.551 170 847 exclusion phecode
743.9
Osteopenia or other disorder of bone and
Osteopenia or other disorder of bone and cartilage
 Musculoskeletal 0.987 0.938 – 1.04 0.602 2300 6345 exclusion phecode
745 Pain in joint Musculoskeletal 0.93 0.892 – 0.971 0.000849 6063 3607 exclusion phecode
747 Cardiac and circulatory congenital anomalies Congenital Anomalies 1.05 0.975 – 1.13 0.196 914 4487 exclusion phecode
747.1 Cardiac congenital anomalies Congenital Anomalies 1.06 0.983 – 1.15 0.125 776 3607 exclusion phecode
747.11 Cardiac shunt/ heart septal defect Congenital Anomalies 0.988 0.864 – 1.13 0.865 282 1284 exclusion phecode
747.12 Valvular heart disease/ heart chambers Congenital Anomalies 1.09 0.972 – 1.22 0.14 391 1587 exclusion phecode
747.13 Congenital anomalies of great vessels Congenital Anomalies 1.21 1.02 – 1.43 0.0318 175 850 exclusion phecode
747.2
Congenital anomalies of peripheral vascular
Congenital anomalies of peripheral vascular system
 Congenital Anomalies 0.996 0.838 – 1.18 0.966 155 956 exclusion phecode
748 Anomalies of respiratory system, congenital Congenital Anomalies 0.933 0.643 – 1.35 0.714 29 224 exclusion phecode
749 Congenital anomalies of face and neck Congenital Anomalies 1.08 0.88 – 1.32 0.476 114 972 exclusion phecode
749.1 Cleft palate Congenital Anomalies 0.93 0.393 – 2.2 0.868 6 122 exclusion phecode
749.2 Congenital anomalies of skull and face bones Congenital Anomalies 1.14 0.701 – 1.87 0.59 20 176 exclusion phecode
750 Digestive congenital anomalies Congenital Anomalies 0.903 0.797 – 1.02 0.108 275 1783 exclusion phecode
750.1 Upper gastrointestinal congenital anomalies Congenital Anomalies 0.944 0.747 – 1.19 0.627 70 682 exclusion phecode
750.11 Esophageal atresia/tracheoesophageal fistula Congenital Anomalies 0.725 0.5 – 1.05 0.0898 30 231 exclusion phecode
750.13 Congenital anomalies of mouth/tongue Congenital Anomalies 0.779 0.483 – 1.26 0.306 15 147 exclusion phecode
750.14 Congenital anomalies of esophagus Congenital Anomalies 0.984 0.691 – 1.4 0.929 29 249 exclusion phecode
750.15 Congenital anomalies of stomach Congenital Anomalies 1.46 0.814 – 2.6 0.206 12 110 exclusion phecode
750.2 Lower gastrointestinal congenital anomalies Congenital Anomalies 0.928 0.8 – 1.08 0.324 204 1147 exclusion phecode
750.21 Congenital anomalies of intestine Congenital Anomalies 0.878 0.719 – 1.07 0.199 110 655 exclusion phecode
750.22
Congenital anomaly of gallbladder, bile ducts
Congenital anomaly of gallbladder, bile ducts, liver, pancreas
 Congenital Anomalies 0.88 0.702 – 1.1 0.264 97 468 exclusion phecode
751 Genitourinary congenital anomalies Congenital Anomalies 0.952 0.875 – 1.04 0.253 646 3888 exclusion phecode
751.1 Congenital anomalies of genital organs Congenital Anomalies 0.99 0.841 – 1.16 0.9 163 1092 exclusion phecode
751.11 Congenital anomalies of female genital organs Congenital Anomalies 0.873 0.719 – 1.06 0.169 110 726 exclusion phecode
751.12 Congenital anomalies of male genital organs Congenital Anomalies 1.18 0.824 – 1.69 0.367 37 312 exclusion phecode
751.2 Congenital anomalies of urinary system Congenital Anomalies 0.935 0.848 – 1.03 0.177 486 2743 exclusion phecode
751.21 Cystic kidney disease Congenital Anomalies 0.908 0.812 – 1.02 0.0938 377 1975 exclusion phecode
751.22 Other specified congenital anomalies of kidney Congenital Anomalies 0.962 0.772 – 1.2 0.734 84 584 exclusion phecode
751.3 Obstructive genitourinary defect Congenital Anomalies 1.17 0.826 – 1.64 0.384 35 335 exclusion phecode
752 Nervous system congenital anomalies Congenital Anomalies 0.933 0.824 – 1.06 0.271 275 2152 exclusion phecode
752.1 Neural tube defects Congenital Anomalies 0.927 0.808 – 1.06 0.283 222 1732 exclusion phecode
752.11 Spina bifida Congenital Anomalies 0.967 0.69 – 1.35 0.844 34 316 exclusion phecode
752.2
Other specified congenital anomalies of nervous
Other specified congenital anomalies of nervous system
 Congenital Anomalies 0.928 0.709 – 1.21 0.587 56 435 exclusion phecode
753 Congenital anomalies of the eye Congenital Anomalies 1 0.787 – 1.27 0.999 79 517 exclusion phecode
753.1 Congenital cataract and lens anomalies Congenital Anomalies 1.03 0.646 – 1.65 0.894 23 152 exclusion phecode
753.2 Congenital anomalies of posterior segment of eye Congenital Anomalies 1.05 0.648 – 1.7 0.844 22 142 exclusion phecode
754 Congenital musculoskeletal deformities of spine Congenital Anomalies 0.92 0.82 – 1.03 0.151 339 2345 exclusion phecode
754.1 Lumbosacral spondylolysis, congenital Congenital Anomalies 0.863 0.63 – 1.18 0.357 52 280 exclusion phecode
754.2 Spondylolisthesis, congenital Congenital Anomalies 0.963 0.811 – 1.14 0.671 148 1069 exclusion phecode
755 Congenital anomalies of limbs Congenital Anomalies 0.961 0.834 – 1.11 0.576 218 1518 exclusion phecode
755.1 Congenital deformities of feet Congenital Anomalies 0.998 0.818 – 1.22 0.988 113 775 exclusion phecode
755.4
Congenital anomalies of upper limb, including
Congenital anomalies of upper limb, including shoulder girdle
 Congenital Anomalies 0.733 0.435 – 1.23 0.242 18 140 exclusion phecode
755.6
Other congenital anomalies of lower limb
Other congenital anomalies of lower limb, including pelvic girdle
 Congenital Anomalies 0.932 0.753 – 1.15 0.521 88 579 exclusion phecode
755.61 Congenital hip dysplasia and deformity Congenital Anomalies 1.02 0.765 – 1.37 0.874 47 350 exclusion phecode
756 Other congenital musculoskeletal anomalies Congenital Anomalies 0.937 0.841 – 1.04 0.237 371 2554 exclusion phecode
756.1 Congenital anomalies of abdominal wall; diaphram Congenital Anomalies 0.857 0.471 – 1.56 0.614 16 116 exclusion phecode
756.2
Pectus and other congenital anomalies of
Pectus and other congenital anomalies of ribs/sternum
 Congenital Anomalies 1.12 0.692 – 1.83 0.637 19 103 exclusion phecode
756.3
Congenital anomalies of muscle, tendon, fascia
Congenital anomalies of muscle, tendon, fascia, and connective tissue
 Congenital Anomalies 0.914 0.743 – 1.13 0.398 94 578 exclusion phecode
756.5 Congenital osteodystrophies Congenital Anomalies 0.957 0.846 – 1.08 0.485 274 1977 exclusion phecode
757 Congenital anomalies of the integument Congenital Anomalies 1.13 0.927 – 1.37 0.227 106 848 exclusion phecode
758 Chromosomal anomalies and genetic disorders Congenital Anomalies 0.919 0.702 – 1.2 0.535 69 396 exclusion phecode
758.1 Chromosomal anomalies Congenital Anomalies 0.868 0.629 – 1.2 0.388 48 298 exclusion phecode
759 Other and unspecified congenital anomalies Congenital Anomalies 1.06 0.897 – 1.26 0.481 158 1067 exclusion phecode
759.1 Anomalies of endocrine glands, congenital Congenital Anomalies 1.13 0.691 – 1.85 0.625 17 150 exclusion phecode
760 Back pain Symptoms 0.957 0.918 – 0.996 0.0333 5007 4666 exclusion phecode
761 Cervicalgia Symptoms 0.957 0.912 – 1 0.0738 2209 7376 exclusion phecode
763
Thoracic or lumbosacral neuritis or
Thoracic or lumbosacral neuritis or radiculitis, unspecified
 Symptoms 0.955 0.898 – 1.02 0.14 1244 5925 exclusion phecode
764 Sciatica Symptoms 0.982 0.924 – 1.04 0.562 1268 5947 exclusion phecode
765 Cervical radiculitis Symptoms 0.934 0.856 – 1.02 0.131 588 3387 exclusion phecode
766 Neuralgia, neuritis, and radiculitis NOS Symptoms 0.937 0.887 – 0.99 0.0197 1611 6710 exclusion phecode
767 Cervicocranial/Cervicobrachial syndrome Symptoms 1.09 0.806 – 1.47 0.581 47 255 exclusion phecode
769 Nonallopathic lesions NEC Symptoms 0.973 0.873 – 1.08 0.62 395 2398 exclusion phecode
770 Myalgia and myositis unspecified Symptoms 0.969 0.918 – 1.02 0.248 1692 6734 exclusion phecode
771 Musculoskeletal symptoms referable to limbs Symptoms 0.946 0.895 – 1 0.0519 1606 5965 exclusion phecode
771.1 Swelling of limb Symptoms 0.962 0.915 – 1.01 0.122 2219 6003 exclusion phecode
771.2 Cramp of limb Symptoms 0.921 0.83 – 1.02 0.123 430 2058 exclusion phecode
772 Symptoms of the muscles Symptoms 0.952 0.878 – 1.03 0.231 718 3865 exclusion phecode
772.1 Muscular wasting and disuse atrophy Symptoms 1.13 0.926 – 1.38 0.227 126 756 exclusion phecode
772.2 Spasm of muscle Symptoms 0.944 0.872 – 1.02 0.148 740 4223 exclusion phecode
772.3 Muscle weakness Symptoms 0.996 0.932 – 1.06 0.902 1081 5232 exclusion phecode
772.4 Rhabdomyolysis Symptoms 1.08 0.828 – 1.4 0.58 66 314 exclusion phecode
772.6 Facial weakness Symptoms 0.931 0.797 – 1.09 0.371 196 939 exclusion phecode
780 Hypothermia/Chills Symptoms 1.1 0.941 – 1.29 0.23 200 1050 exclusion phecode
781
Symptoms involving nervous and musculoskeletal
Symptoms involving nervous and musculoskeletal systems
 Symptoms 0.98 0.918 – 1.05 0.537 1127 5294 exclusion phecode
781.1 Loss of height Symptoms 0.936 0.704 – 1.24 0.65 61 298 exclusion phecode
781.2 Abnormal posture Symptoms 0.857 0.537 – 1.37 0.516 24 121 exclusion phecode
782.3 Edema Symptoms 0.995 0.948 – 1.04 0.847 2356 6474 exclusion phecode
782.6 Pallor and flushing Symptoms 0.981 0.862 – 1.12 0.765 265 1624 exclusion phecode
783 Fever of unknown origin Symptoms 1.05 1 – 1.11 0.0367 2137 7433 exclusion phecode
783.1 Postprocedural fever Symptoms 0.95 0.749 – 1.21 0.675 85 523 exclusion phecode
785 Abdominal pain Symptoms 0.957 0.918 – 0.997 0.035 5240 4431 exclusion phecode
788 Syncope and collapse Symptoms 1.05 0.989 – 1.11 0.114 1525 6931 exclusion phecode
789 Nausea and vomiting Symptoms 1.03 0.988 – 1.08 0.156 3148 6487 exclusion phecode
789.1 Persistent vomiting Symptoms 1.02 0.891 – 1.16 0.819 271 1389 exclusion phecode
790 Nonspecific findings on examination of blood Symptoms 1.06 0.986 – 1.13 0.122 1067 3880 exclusion phecode
790.1 Elevated sedimentation rate Symptoms 1.07 0.853 – 1.34 0.567 94 413 exclusion phecode
790.6 Other abnormal blood chemistry Symptoms 1.03 0.986 – 1.08 0.183 3143 6106 exclusion phecode
790.8 Elevated C-reactive protein (CRP) Symptoms 0.945 0.774 – 1.15 0.58 112 499 exclusion phecode
790.9 Abnormal arterial blood gases Symptoms 0.981 0.753 – 1.28 0.89 62 263 exclusion phecode
791 Gangrene Symptoms 1.08 0.895 – 1.29 0.437 153 748 exclusion phecode
792
Abnormal Papanicolaou smear of cervix and
Abnormal Papanicolaou smear of cervix and cervical HPV
 Genitourinary 0.942 0.869 – 1.02 0.149 815 2438 exclusion phecode
792.1
Papanicolaou smear of cervix or vagina with
Papanicolaou smear of cervix or vagina with atypical squamous cells
 Genitourinary 1.01 0.899 – 1.15 0.814 344 1547 exclusion phecode
794
Abnormal results of other function studies
Abnormal results of other function studies (bladder, pancreas, placenta, spleen, etc)
 Symptoms 0.934 0.762 – 1.14 0.509 106 1006 exclusion phecode
795
Other and nonspecific abnormal cytological
Other and nonspecific abnormal cytological, histological and immunological findings
 Symptoms 1.03 0.949 – 1.13 0.447 606 3797 exclusion phecode
795.8 Abnormal tumor markers Symptoms 0.932 0.844 – 1.03 0.162 458 3468 exclusion phecode
795.81 Elevated carcinoembryonic antigen [CEA] Symptoms 1.27 0.749 – 2.17 0.372 15 131 exclusion phecode
795.82 Elevated cancer antigen 125 [CA 125] Symptoms 0.711 0.498 – 1.01 0.06 37 339 exclusion phecode
796 Elevated prostate specific antigen [PSA] Genitourinary 0.899 0.818 – 0.988 0.0276 616 2005 exclusion phecode
797 Shock Symptoms 1.05 0.929 – 1.19 0.421 301 1358 exclusion phecode
797.1 Cardiogenic shock Symptoms 1.02 0.849 – 1.23 0.816 156 599 exclusion phecode
798 Malaise and fatigue Symptoms 0.994 0.954 – 1.04 0.783 4173 5496 exclusion phecode
798.1 Chronic fatigue syndrome Symptoms 0.969 0.892 – 1.05 0.457 700 2949 exclusion phecode
800 Fracture of lower limb Injuries & Poisonings 0.953 0.88 – 1.03 0.238 694 4223 exclusion phecode
800.1 Fracture of neck of femur Injuries & Poisonings 0.952 0.817 – 1.11 0.532 178 962 exclusion phecode
800.2 Fracture of unspecified part of femur Injuries & Poisonings 0.98 0.843 – 1.14 0.789 196 1206 exclusion phecode
800.3 Fracture of tibia and fibula Injuries & Poisonings 0.948 0.83 – 1.08 0.436 252 1568 exclusion phecode
800.4 Fracture of patella Injuries & Poisonings 0.942 0.773 – 1.15 0.548 113 622 exclusion phecode
801 Fracture of ankle and foot Injuries & Poisonings 0.951 0.884 – 1.02 0.173 861 4449 exclusion phecode
801.1 Fracture of foot Injuries & Poisonings 0.922 0.825 – 1.03 0.153 339 2087 exclusion phecode
802 Fracture of pelvis Injuries & Poisonings 0.975 0.793 – 1.2 0.808 102 648 exclusion phecode
803 Fracture of upper limb Injuries & Poisonings 0.894 0.82 – 0.974 0.0101 594 3705 exclusion phecode
803.1 Fracture of humerus Injuries & Poisonings 0.919 0.794 – 1.06 0.254 213 1283 exclusion phecode
803.2 Fracture of radius and ulna Injuries & Poisonings 0.888 0.791 – 0.996 0.0433 334 2042 exclusion phecode
803.21 Colles' fracture Injuries & Poisonings 0.748 0.6 – 0.933 0.0101 87 520 exclusion phecode
803.3 Fracture of clavicle or scapula Injuries & Poisonings 0.874 0.726 – 1.05 0.154 134 903 exclusion phecode
804 Fracture of hand or wrist Injuries & Poisonings 0.98 0.892 – 1.08 0.681 516 3008 exclusion phecode
805
Fracture of vertebral column without mention of
Fracture of vertebral column without mention of spinal cord injury
 Injuries & Poisonings 1.05 0.941 – 1.17 0.396 398 2379 exclusion phecode
807 Fracture of ribs Injuries & Poisonings 1.06 0.93 – 1.21 0.386 262 1352 exclusion phecode
809 Fracture of unspecified bones Injuries & Poisonings 0.963 0.895 – 1.04 0.312 839 5265 exclusion phecode
816 Cerebral laceration and contusion Injuries & Poisonings 0.887 0.536 – 1.47 0.642 17 109 exclusion phecode
817 Concussion Injuries & Poisonings 1.07 0.95 – 1.2 0.268 353 2066 exclusion phecode
818 Intracranial hemorrhage (injury) Injuries & Poisonings 0.931 0.769 – 1.13 0.461 119 728 exclusion phecode
818.1 Subdural hemorrhage (injury) Injuries & Poisonings 0.827 0.568 – 1.2 0.322 32 199 exclusion phecode
818.2 Subarachnoid hemorrhage (injury) Injuries & Poisonings 1.27 0.865 – 1.86 0.223 32 244 exclusion phecode
819
Skull and face fracture and other intercranial
Skull and face fracture and other intercranial injury
 Injuries & Poisonings 1.03 0.952 – 1.12 0.429 671 4482 exclusion phecode
830 Dislocation Injuries & Poisonings 0.952 0.894 – 1.02 0.135 1115 6642 exclusion phecode
835 Internal derangement of knee Injuries & Poisonings 0.969 0.894 – 1.05 0.433 711 4300 exclusion phecode
836 Traumatic arthropathy Injuries & Poisonings 0.946 0.789 – 1.13 0.55 148 908 exclusion phecode
840 Sprains and strains Injuries & Poisonings 0.943 0.901 – 0.987 0.0125 2569 6735 exclusion phecode
840.1 Muscle/tendon sprain Injuries & Poisonings 0.908 0.779 – 1.06 0.214 199 985 exclusion phecode
840.2 Rotator cuff (capsule) sprain Injuries & Poisonings 0.865 0.792 – 0.946 0.00148 574 3052 exclusion phecode
840.3 Joint/ligament sprain Injuries & Poisonings 0.912 0.847 – 0.982 0.0149 858 4465 exclusion phecode
841 Sprains and strains of back and neck Injuries & Poisonings 0.868 0.796 – 0.945 0.00117 647 3056 exclusion phecode
842 Other sprains and strains Injuries & Poisonings 0.971 0.88 – 1.07 0.548 499 2574 exclusion phecode
850 Hemorrhage or hematoma complicating a procedure Injuries & Poisonings 1.03 0.95 – 1.12 0.442 648 3586 exclusion phecode
851
Complications of transplants and reattached
Complications of transplants and reattached limbs
 Injuries & Poisonings 1.05 0.983 – 1.12 0.141 1087 4834 exclusion phecode
853 Complication of colostomy or enterostomy Injuries & Poisonings 1.16 0.964 – 1.41 0.115 132 681 exclusion phecode
854
Complications of cardiac/vascular device
Complications of cardiac/vascular device, implant, and graft
 Injuries & Poisonings 1.11 1.03 – 1.2 0.00488 895 3683 exclusion phecode
855
Complication of nervous system device, implant
Complication of nervous system device, implant, and graft
 Injuries & Poisonings 1.52 1.09 – 2.14 0.0148 47 417 exclusion phecode
856
Vascular complications of surgery and medical
Vascular complications of surgery and medical procedures
 Injuries & Poisonings 1.04 0.847 – 1.28 0.707 121 513 exclusion phecode
857
Mechanical complication of unspecified
Mechanical complication of unspecified genitourinary device, implant, and graft
 Injuries & Poisonings 1.06 0.949 – 1.19 0.29 359 2342 exclusion phecode
858 Complication of internal orthopedic device Injuries & Poisonings 0.98 0.887 – 1.08 0.682 442 3458 exclusion phecode
859
Complication due to other implant and internal
Complication due to other implant and internal device
 Injuries & Poisonings 1.09 0.999 – 1.2 0.0536 532 3638 exclusion phecode
860 Bone marrow or stem cell transplant Neoplasms 0.921 0.699 – 1.21 0.56 68 403 exclusion phecode
870 Open wounds of head; neck; and trunk Injuries & Poisonings 0.993 0.935 – 1.05 0.812 1258 6694 exclusion phecode
870.1 Open wound or laceration of eye or eyelid Injuries & Poisonings 1.17 0.897 – 1.52 0.252 64 432 exclusion phecode
870.2 Open wound of ear Injuries & Poisonings 1.15 0.828 – 1.61 0.398 45 251 exclusion phecode
870.3 Other open wound of head and face Injuries & Poisonings 0.898 0.807 – 1 0.0499 385 2549 exclusion phecode
870.4 Open wound of nose and sinus Injuries & Poisonings 0.893 0.643 – 1.24 0.5 41 368 exclusion phecode
870.5 Open wound of lip and mouth Injuries & Poisonings 0.922 0.704 – 1.21 0.555 58 482 exclusion phecode
870.6 Open wound of neck Injuries & Poisonings 0.769 0.536 – 1.1 0.156 33 362 exclusion phecode
870.8 Open wound of genital organs Injuries & Poisonings 1.08 0.747 – 1.56 0.687 28 267 exclusion phecode
871 Open wounds of extremities Injuries & Poisonings 0.97 0.913 – 1.03 0.33 1288 6257 exclusion phecode
871.1 Open wound of hand except finger(s) Injuries & Poisonings 0.979 0.839 – 1.14 0.79 190 1106 exclusion phecode
871.2 Open wound of finger(s) Injuries & Poisonings 0.918 0.821 – 1.03 0.133 369 2169 exclusion phecode
871.3 Open wound of foot except toe(s) alone Injuries & Poisonings 1.02 0.886 – 1.18 0.775 253 1255 exclusion phecode
871.4 Open wound of toe(s) Injuries & Poisonings 1.07 0.899 – 1.27 0.447 171 860 exclusion phecode
872 Traumatic amputation Injuries & Poisonings 1.02 0.883 – 1.18 0.787 230 1228 exclusion phecode
874 Complication of amputation stump Injuries & Poisonings 0.926 0.73 – 1.18 0.53 83 384 exclusion phecode
875 Non-healing surgical wound Injuries & Poisonings 1 0.843 – 1.19 0.972 164 1017 exclusion phecode
876
Posttraumatic wound infection not elsewhere
Posttraumatic wound infection not elsewhere classified
 Injuries & Poisonings 1.08 0.959 – 1.23 0.196 287 1574 exclusion phecode
907 Injuries to the nervous system Injuries & Poisonings 0.99 0.861 – 1.14 0.893 219 1928 exclusion phecode
910 Superficial injury, infected Injuries & Poisonings 1.2 0.9 – 1.61 0.21 61 271 exclusion phecode
911 Blister Injuries & Poisonings 0.952 0.808 – 1.12 0.555 170 927 exclusion phecode
912 Insect bite Injuries & Poisonings 0.847 0.733 – 0.979 0.0246 205 1157 exclusion phecode
913 Toxic effect of venom Injuries & Poisonings 0.817 0.681 – 0.981 0.0303 144 743 exclusion phecode
916 Contusion Injuries & Poisonings 0.971 0.921 – 1.02 0.276 1729 7132 exclusion phecode
930 Allergic reaction to food Injuries & Poisonings 0.889 0.779 – 1.01 0.081 279 1161 exclusion phecode
931
Contact dermatitis and other eczema due to
Contact dermatitis and other eczema due to plants [except food]
 Dermatologic 0.799 0.694 – 0.921 0.00194 239 1217 exclusion phecode
938 Dermatitis due to solar radiation Dermatologic 0.937 0.889 – 0.988 0.0162 2085 4391 exclusion phecode
938.1 Acute dermatitis due to solar radiation Dermatologic 0.856 0.667 – 1.1 0.223 80 329 exclusion phecode
938.2 Chronic dermatitis due to solar radiation Dermatologic 0.939 0.89 – 0.991 0.0214 2009 4330 exclusion phecode
939
Atopic/contact dermatitis due to other or
Atopic/contact dermatitis due to other or unspecified
 Dermatologic 0.965 0.919 – 1.01 0.15 2549 4785 exclusion phecode
939.1 Contact and allergic dermatitis of eyelid Dermatologic 0.896 0.623 – 1.29 0.556 35 159 exclusion phecode
941 Adverse reaction to serum or vaccine Injuries & Poisonings 1.09 0.845 – 1.41 0.497 75 324 exclusion phecode
942 Infusion and transfusion reaction Injuries & Poisonings 1.11 0.893 – 1.38 0.347 114 425 exclusion phecode
946 Anaphylactic shock NOS Injuries & Poisonings 0.852 0.727 – 1 0.0494 195 874 exclusion phecode
947 Urticaria Dermatologic 1.02 0.914 – 1.14 0.716 401 1826 exclusion phecode
949 Allergies, other Injuries & Poisonings 0.967 0.92 – 1.02 0.188 2455 4784 exclusion phecode
952
Spinal cord injury without evidence of spinal
Spinal cord injury without evidence of spinal bone injury
 Injuries & Poisonings 1.08 0.882 – 1.32 0.46 114 973 exclusion phecode
957 Injury to other and unspecified nerves Injuries & Poisonings 0.72 0.476 – 1.09 0.118 25 242 exclusion phecode
958
Certain early complications of trauma or
Certain early complications of trauma or procedure
 Injuries & Poisonings 1.1 0.979 – 1.23 0.113 369 2396 exclusion phecode
958.1 Postoperative shock Injuries & Poisonings 1.25 0.957 – 1.63 0.101 74 339 exclusion phecode
958.2 Traumatic and surgical subcutaneous emphysema Injuries & Poisonings 1.21 0.813 – 1.81 0.344 28 239 exclusion phecode
960 Poisoning by antibiotics Injuries & Poisonings 0.973 0.901 – 1.05 0.487 776 3940 exclusion phecode
960.1
Adverse effects of antibacterials (not
Adverse effects of antibacterials (not penicillins)
 Injuries & Poisonings 0.99 0.828 – 1.18 0.91 143 692 exclusion phecode
960.2 Allergy/adverse effect of penicillin Injuries & Poisonings 0.998 0.908 – 1.1 0.972 490 2760 exclusion phecode
961 Poisoning by other anti-infectives Injuries & Poisonings 1.02 0.871 – 1.19 0.808 196 913 exclusion phecode
961.1 Poisoning/allergy of sulfonamides Injuries & Poisonings 0.979 0.872 – 1.1 0.718 320 1810 exclusion phecode
962 Poisoning by hormones and synthetic substitutes Injuries & Poisonings 1.06 0.948 – 1.19 0.297 358 1711 exclusion phecode
962.1
Adrenal cortical steroids causing adverse
Adrenal cortical steroids causing adverse effects in therapeutic use
 Injuries & Poisonings 1.04 0.881 – 1.23 0.642 178 770 exclusion phecode
962.2
Insulins and antidiabetic agents causing
Insulins and antidiabetic agents causing adverse effects in therapeutic use
 Injuries & Poisonings 1.02 0.725 – 1.44 0.896 41 226 exclusion phecode
962.3
Hormones and synthetic substitutes causing
Hormones and synthetic substitutes causing adverse effects in therapeutic use
 Injuries & Poisonings 1.08 0.928 – 1.25 0.323 194 1032 exclusion phecode
963 Poisoning by primarily systemic agents Injuries & Poisonings 1.05 0.968 – 1.14 0.245 728 4057 exclusion phecode
963.1
Antineoplastic and immunosuppressive drugs
Antineoplastic and immunosuppressive drugs causing adverse effects
 Injuries & Poisonings 1.07 0.991 – 1.17 0.0836 702 3964 exclusion phecode
964
Poisoning by agents primarily affecting blood
Poisoning by agents primarily affecting blood constituents
 Injuries & Poisonings 0.988 0.883 – 1.11 0.835 379 1547 exclusion phecode
964.1 Anticoagulants causing adverse effects Injuries & Poisonings 0.963 0.859 – 1.08 0.517 362 1482 exclusion phecode
965
Poisoning by analgesics, antipyretics, and
Poisoning by analgesics, antipyretics, and antirheumatics
 Injuries & Poisonings 1.1 0.966 – 1.24 0.156 297 1465 exclusion phecode
965.1
Opiates and related narcotics causing adverse
Opiates and related narcotics causing adverse effects in therapeutic use
 Injuries & Poisonings 0.988 0.895 – 1.09 0.82 454 2386 exclusion phecode
965.3
Salicylates causing adverse effects in
Salicylates causing adverse effects in therapeutic use
 Injuries & Poisonings 0.974 0.685 – 1.39 0.886 33 207 exclusion phecode
966
Poisoning by anticonvulsants and
Poisoning by anticonvulsants and anti-Parkinsonism drugs
 Injuries & Poisonings 0.8 0.558 – 1.15 0.223 29 187 exclusion phecode
967
Adverse effects of sedatives or other central
Adverse effects of sedatives or other central nervous system depressants and anesthetics
 Injuries & Poisonings 0.981 0.875 – 1.1 0.741 328 2129 exclusion phecode
969 Poisoning by psychotropic agents Injuries & Poisonings 1 0.802 – 1.25 0.999 110 471 exclusion phecode
971
Poisoning by drugs primarily affecting the
Poisoning by drugs primarily affecting the autonomic nervous system
 Injuries & Poisonings 0.821 0.519 – 1.3 0.399 37 162 exclusion phecode
972
Poisoning by agents primarily affecting the
Poisoning by agents primarily affecting the cardiovascular system
 Injuries & Poisonings 0.947 0.798 – 1.13 0.538 157 615 exclusion phecode
972.1
Cardiac rhythm regulators causing adverse
Cardiac rhythm regulators causing adverse effects in therapeutic use
 Injuries & Poisonings 0.946 0.682 – 1.31 0.741 46 166 exclusion phecode
972.6 Antihypertensive agents causing adverse effects Injuries & Poisonings 0.889 0.678 – 1.16 0.393 67 219 exclusion phecode
974
Poisoning by water, mineral, and uric acid
Poisoning by water, mineral, and uric acid metabolism drugs
 Injuries & Poisonings 1 0.755 – 1.33 0.991 68 275 exclusion phecode
975
Poisoning by agents primarily acting on the
Poisoning by agents primarily acting on the smooth and skeletal muscles and respiratory system
 Injuries & Poisonings 0.721 0.484 – 1.07 0.106 32 135 exclusion phecode
976
Poisoning by agents primarily affecting skin &
Poisoning by agents primarily affecting skin & mucous membrane, ophthalmological, otorhinolaryngological, & dental drugs
 Injuries & Poisonings 1.29 0.867 – 1.91 0.212 30 138 exclusion phecode
977 Personal history of allergy to medicinal agents Injuries & Poisonings 1.03 0.947 – 1.13 0.451 615 2916 exclusion phecode
979 Adverse drug events and drug allergies Injuries & Poisonings 0.994 0.934 – 1.06 0.836 1234 5603 exclusion phecode
980
Encounter for long-term (current) use of
Encounter for long-term (current) use of antibiotics
 Infectious Diseases 1.01 0.908 – 1.11 0.916 422 3000 exclusion phecode
985 Toxic effect of other metals Injuries & Poisonings 1.56 0.918 – 2.65 0.1 19 129 exclusion phecode
989
Toxic effect of other substances, chiefly
Toxic effect of other substances, chiefly nonmedicinal as to source
 Injuries & Poisonings 0.87 0.647 – 1.17 0.36 48 333 exclusion phecode
990 Effects radiation NOS Injuries & Poisonings 1.01 0.939 – 1.09 0.725 755 5841 exclusion phecode
994 Sepsis and SIRS Injuries & Poisonings 1.05 0.98 – 1.13 0.155 883 4532 exclusion phecode
994.1 Systemic inflammatory response syndrome (SIRS) Injuries & Poisonings 0.992 0.813 – 1.21 0.933 120 633 exclusion phecode
994.2 Sepsis Injuries & Poisonings 1.05 0.976 – 1.13 0.192 849 4334 exclusion phecode
994.21 Septic shock Injuries & Poisonings 1.03 0.905 – 1.16 0.693 295 1278 exclusion phecode
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