Departments of Anesthesiology and Biostatistics | University of Michigan

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Scores Direct LDL cholesterol (mmol/L) Michigan Genomics Initiative Freeze 3 (MGI) PheWAS analysis

Direct LDL cholesterol (mmol/L) — Michigan Genomics Initiative Freeze 3 (MGI) PRS PheWAS

PRS model
PRS ID exprsweb-ldl-30780-raw-lassosum-mgi-freeze3-20211120Legacy LASSOSUMlassosumUK Biobank GWAS

Evaluation cohort: Michigan Genomics Initiative Freeze 3 (MGI).

This page pairs the PheWAS plot with the full sortable table for the all-subject and exclusion scans.

Read the all-subject and exclusion scans separately. The combined view is only a browsing aid, and the selected-phecode panel below is only meaningful when the same phecode exists in both scans.

ExPRS exclusion definition

Exclusion cohort: normal-range subset (0.01-100).

For this ExPRS, the exclusion sensitivity scan keeps only the study's normal-range subset for Direct LDL cholesterol (mmol/L) (0.01-100) before rerunning the PheWAS. This is an exposure-based sensitivity analysis rather than a diagnosis-based exclusion.

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Signal overview

The plot gives a quick view of the currently visible associations. Click a point to pin its details, inspect that phecode across scans when both rows exist, or open the matching phecode detail page.

131 rows visible 16 categories
Phecode Description Category OR 95% CI P value Cases Controls Analysis Link
008 Intestinal infection Infectious Diseases 0.98 0.944 – 1.02 0.304 3004 29292 all phecode
008.5 Bacterial enteritis Infectious Diseases 0.98 0.925 – 1.04 0.485 1322 13162 all phecode
008.52 Intestinal infection due to C. difficile Infectious Diseases 0.998 0.936 – 1.06 0.962 1046 10455 all phecode
008.6 Viral Enteritis Infectious Diseases 1 0.931 – 1.08 0.939 770 7676 all phecode
010 Tuberculosis Infectious Diseases 0.958 0.84 – 1.09 0.524 244 2425 all phecode
031 Diseases due to other mycobacteria Infectious Diseases 0.854 0.682 – 1.07 0.166 86 855 all phecode
038 Septicemia Infectious Diseases 1 0.964 – 1.05 0.856 2582 24779 all phecode
038.1 Gram negative septicemia Infectious Diseases 0.967 0.887 – 1.05 0.451 568 5629 all phecode
038.2 Gram positive septicemia Infectious Diseases 0.994 0.87 – 1.14 0.934 235 2350 all phecode
038.3 Bacteremia Infectious Diseases 1 0.944 – 1.06 0.941 1210 12079 all phecode
041 Bacterial infection NOS Infectious Diseases 1.01 0.979 – 1.03 0.659 5750 38799 all phecode
041.1 Staphylococcus infections Infectious Diseases 0.989 0.941 – 1.04 0.675 1707 16977 all phecode
041.11 Methicillin sensitive Staphylococcus aureus Infectious Diseases 0.966 0.902 – 1.03 0.316 920 9192 all phecode
041.12 Methicillin resistant Staphylococcus aureus Infectious Diseases 1.01 0.935 – 1.08 0.854 783 7812 all phecode
041.2 Streptococcus infection Infectious Diseases 0.964 0.916 – 1.02 0.166 1632 16287 all phecode
041.21 Rheumatic fever / chorea Infectious Diseases 1.01 0.886 – 1.15 0.901 257 2554 all phecode
041.4 E. coli Infectious Diseases 1.02 0.956 – 1.08 0.613 1175 11680 all phecode
041.8 H. pylori Infectious Diseases 1.02 0.895 – 1.16 0.786 257 2521 all phecode
041.9 Infection with drug-resistant microorganisms Infectious Diseases 1.02 0.913 – 1.13 0.778 387 3864 all phecode
053 Herpes zoster Infectious Diseases 1 0.952 – 1.06 0.912 1560 15184 all phecode
053.1 Herpes zoster with nervous system complications Infectious Diseases 0.903 0.785 – 1.04 0.15 220 2169 all phecode
054 Herpes simplex Infectious Diseases 1 0.951 – 1.05 0.961 1593 15600 all phecode
070 Viral hepatitis Infectious Diseases 0.989 0.92 – 1.06 0.755 829 8280 all phecode
070.1 Viral hepatitis A Infectious Diseases 0.931 0.74 – 1.17 0.542 87 860 all phecode
070.2 Viral hepatitis B Infectious Diseases 0.979 0.85 – 1.13 0.763 215 2138 all phecode
070.3 Viral hepatitis C Infectious Diseases 0.97 0.887 – 1.06 0.506 528 5280 all phecode
070.4 Chronic hepatitis Infectious Diseases 0.941 0.813 – 1.09 0.419 197 1964 all phecode
070.9 Hepatitis NOS Infectious Diseases 0.978 0.92 – 1.04 0.483 1145 11381 all phecode
071 Human immunodeficiency virus [HIV] disease Infectious Diseases 1.1 0.926 – 1.3 0.286 145 1450 all phecode
071.1 HIV infection, symptomatic Infectious Diseases 1.17 0.963 – 1.42 0.116 117 1163 all phecode
078 Viral warts & HPV Infectious Diseases 0.997 0.962 – 1.03 0.88 3434 29624 all phecode
079 Viral infection Infectious Diseases 1.02 0.994 – 1.05 0.131 6664 35342 all phecode
079.1 Varicella infection Infectious Diseases 1.02 0.985 – 1.05 0.269 3793 31251 all phecode
079.2 Infectious mononucleosis Infectious Diseases 1.04 0.92 – 1.18 0.522 283 2723 all phecode
079.9 Viremia, NOS Infectious Diseases 1.02 0.949 – 1.09 0.604 838 8253 all phecode
080 Postoperative infection Infectious Diseases 0.989 0.949 – 1.03 0.579 2619 26065 all phecode
081
Infection/inflammation of internal prosthetic
Infection/inflammation of internal prosthetic device; implant; and graft
 Infectious Diseases 0.953 0.904 – 1 0.068 1589 15884 all phecode
090
Sexually transmitted infections (not HIV or
Sexually transmitted infections (not HIV or hepatitis)
 Infectious Diseases 1.05 0.982 – 1.12 0.158 965 9630 all phecode
110 Dermatophytosis / Dermatomycosis Infectious Diseases 0.992 0.957 – 1.03 0.649 3544 30054 all phecode
110.1 Dermatophytosis Infectious Diseases 0.995 0.959 – 1.03 0.795 3241 27244 all phecode
110.11 Dermatophytosis of nail Infectious Diseases 1.01 0.961 – 1.06 0.773 2044 16765 all phecode
110.12 Althete's foot Infectious Diseases 1.01 0.941 – 1.08 0.803 899 8043 all phecode
110.13 Dermatophytosis of the body Infectious Diseases 1.02 0.946 – 1.1 0.633 790 7827 all phecode
110.2 Dermatomycoses Infectious Diseases 0.958 0.864 – 1.06 0.407 398 3971 all phecode
112 Candidiasis Infectious Diseases 0.994 0.96 – 1.03 0.721 3685 30495 all phecode
112.3 Candidiasis of skin and nails Infectious Diseases 0.981 0.906 – 1.06 0.63 682 6732 all phecode
117 Mycoses Infectious Diseases 1.01 0.929 – 1.1 0.802 608 6069 all phecode
117.1 Histoplasmosis Infectious Diseases 1.04 0.829 – 1.31 0.726 81 801 all phecode
117.4 Aspergillosis Infectious Diseases 1.1 0.922 – 1.31 0.287 140 1387 all phecode
130 Spirochetal infection Infectious Diseases 0.95 0.809 – 1.11 0.528 168 1677 all phecode
130.1 Lyme disease Infectious Diseases 1.01 0.838 – 1.23 0.883 116 1160 all phecode
131 Protozoan infection Infectious Diseases 0.95 0.729 – 1.24 0.703 61 610 all phecode
132 Infestation (lice, mites) Infectious Diseases 0.901 0.777 – 1.04 0.166 195 1948 all phecode
134 Helminthiases Infectious Diseases 0.904 0.727 – 1.12 0.362 83 812 all phecode
134.1 Intestinal helminthiases Infectious Diseases 0.934 0.712 – 1.23 0.621 53 513 all phecode
136 Other infectious and parasitic diseases Infectious Diseases 0.993 0.958 – 1.03 0.697 3279 32486 all phecode
145 Cancer of mouth Neoplasms 0.972 0.922 – 1.03 0.303 1481 14725 all phecode
145.1 Cancer of lip Neoplasms 0.909 0.724 – 1.14 0.415 76 750 all phecode
145.2 Cancer of tongue Neoplasms 0.944 0.871 – 1.02 0.159 645 6430 all phecode
145.3 Cancer of major salivary glands Neoplasms 1.03 0.919 – 1.15 0.648 361 3597 all phecode
145.4 Cancer of the gums Neoplasms 0.897 0.765 – 1.05 0.176 166 1632 all phecode
145.5 Cancer of the mouth floor Neoplasms 0.9 0.783 – 1.04 0.141 206 2048 all phecode
149 Cancer of larynx, pharynx, nasal cavities Neoplasms 0.961 0.908 – 1.02 0.177 1290 12873 all phecode
149.1 Cancer of oropharynx Neoplasms 1.05 0.941 – 1.17 0.384 350 3499 all phecode
149.2 Cancer of nasopharynx Neoplasms 0.89 0.725 – 1.09 0.265 100 1000 all phecode
149.3 Cancer of hypopharynx Neoplasms 1.12 0.896 – 1.4 0.322 82 819 all phecode
149.4 Cancer of larynx Neoplasms 0.961 0.866 – 1.07 0.448 386 3857 all phecode
149.5
Hx of malignant neoplasm of oral cavity and
Hx of malignant neoplasm of oral cavity and pharynx
 Neoplasms 0.917 0.841 – 1 0.0525 552 5505 all phecode
149.9 Cancer of of nasal cavities Neoplasms 0.964 0.844 – 1.1 0.589 240 2398 all phecode
150 Cancer of esophagus Neoplasms 0.991 0.898 – 1.09 0.862 433 4315 all phecode
151 Cancer of stomach Neoplasms 0.993 0.906 – 1.09 0.884 498 4962 all phecode
153 Colorectal cancer Neoplasms 1.05 0.997 – 1.11 0.0644 1458 14383 all phecode
153.2 Colon cancer Neoplasms 1.07 1.01 – 1.14 0.0323 1160 11472 all phecode
153.3
Malignant neoplasm of rectum, rectosigmoid
Malignant neoplasm of rectum, rectosigmoid junction, and anus
 Neoplasms 1.03 0.961 – 1.11 0.367 815 8093 all phecode
155 Cancer of liver and intrahepatic bile duct Neoplasms 1.02 0.932 – 1.12 0.648 511 5097 all phecode
155.1 Malignant neoplasm of liver, primary Neoplasms 1.01 0.899 – 1.13 0.896 344 3433 all phecode
157 Pancreatic cancer Neoplasms 0.972 0.887 – 1.07 0.542 503 5005 all phecode
158
Neoplasm of unspecified nature of digestive
Neoplasm of unspecified nature of digestive system
 Neoplasms 0.954 0.906 – 1 0.0723 1623 15759 all phecode
159
Malignant neoplasm of other and ill-defined
Malignant neoplasm of other and ill-defined sites within the digestive organs and peritoneum
 Neoplasms 1.03 0.977 – 1.08 0.307 1818 17869 all phecode
159.2
Malignant neoplasm of small intestine
Malignant neoplasm of small intestine, including duodenum
 Neoplasms 1.24 1.08 – 1.42 0.0024 221 2206 all phecode
159.3
Malignant neoplasm of gallbladder and
Malignant neoplasm of gallbladder and extrahepatic bile ducts
 Neoplasms 0.915 0.776 – 1.08 0.295 158 1578 all phecode
159.4
Malignant neoplasm of retroperitoneum and
Malignant neoplasm of retroperitoneum and peritoneum
 Neoplasms 1.03 0.917 – 1.16 0.589 293 2920 all phecode
164 Cancer of intrathoracic organs Neoplasms 1.04 0.871 – 1.23 0.693 133 1324 all phecode
165 Cancer within the respiratory system Neoplasms 0.99 0.935 – 1.05 0.714 1336 13340 all phecode
165.1 Cancer of bronchus; lung Neoplasms 0.982 0.922 – 1.05 0.581 1057 10552 all phecode
170 Cancer of bone and connective tissue Neoplasms 0.997 0.95 – 1.05 0.908 1792 17850 all phecode
170.1 Bone cancer Neoplasms 0.929 0.862 – 1 0.0489 773 7690 all phecode
170.2 Cancer of connective tissue Neoplasms 1.01 0.955 – 1.07 0.669 1266 12632 all phecode
172 Skin cancer Neoplasms 0.984 0.96 – 1.01 0.201 8608 33186 all phecode
172.1 Melanomas of skin, dx or hx Neoplasms 0.986 0.957 – 1.02 0.369 5330 30106 all phecode
172.11 Melanomas of skin Neoplasms 0.977 0.941 – 1.01 0.229 3100 25064 all phecode
172.2 Other non-epithelial cancer of skin Neoplasms 0.98 0.954 – 1.01 0.145 7095 30462 all phecode
172.21 Basal cell carcinoma Neoplasms 1.01 0.977 – 1.05 0.517 3690 23868 all phecode
172.22 Squamous cell carcinoma Neoplasms 1 0.958 – 1.04 0.994 2414 17683 all phecode
172.3 Carcinoma in situ of skin Neoplasms 1.05 0.991 – 1.1 0.105 1482 12326 all phecode
173 Neoplasm of uncertain behavior of skin Neoplasms 1.01 0.96 – 1.05 0.812 1997 18755 all phecode
174 Breast cancer Neoplasms 1.01 0.974 – 1.05 0.531 3186 15514 all phecode
174.1 Breast cancer [female] Neoplasms 1.02 0.98 – 1.06 0.337 3036 14701 all phecode
174.11 Malignant neoplasm of female breast Neoplasms 1.02 0.985 – 1.07 0.229 2991 14639 all phecode
174.3 Neoplasm of uncertain behavior of breast Neoplasms 1.14 0.995 – 1.3 0.0597 233 2307 all phecode
175 Acquired absence of breast Neoplasms 1.04 0.972 – 1.12 0.252 919 8920 all phecode
180 Cervical cancer and dysplasia Neoplasms 0.994 0.94 – 1.05 0.827 1431 12185 all phecode
180.1 Cervical cancer Neoplasms 0.972 0.886 – 1.07 0.542 500 4982 all phecode
180.3
Cervical intraepithelial neoplasia [CIN]
Cervical intraepithelial neoplasia [CIN] [Cervical dysplasia]
 Neoplasms 0.989 0.927 – 1.05 0.727 1048 9323 all phecode
182 Malignant neoplasm of uterus Neoplasms 0.946 0.877 – 1.02 0.146 765 7613 all phecode
184 Cancer of other female genital organs Neoplasms 0.969 0.913 – 1.03 0.308 1191 11592 all phecode
184.1
Malignant neoplasm of ovary and other uterine
Malignant neoplasm of ovary and other uterine adnexa
 Neoplasms 0.968 0.887 – 1.06 0.458 573 5719 all phecode
184.11 Malignant neoplasm of ovary Neoplasms 0.998 0.903 – 1.1 0.973 432 4309 all phecode
184.2
Cancer of other female genital organs
Cancer of other female genital organs (excluding uterus and ovary)
 Neoplasms 0.921 0.847 – 1 0.0543 608 6057 all phecode
185 Cancer of prostate Neoplasms 1.01 0.969 – 1.06 0.592 2901 10342 all phecode
187 Cancer of other male genital organs Neoplasms 0.99 0.886 – 1.11 0.855 339 3384 all phecode
187.1
Malignant neoplasm of unspecified male genital
Malignant neoplasm of unspecified male genital organ
 Neoplasms 1.08 0.893 – 1.32 0.413 115 1141 all phecode
187.2 Malignant neoplasm of testis Neoplasms 0.92 0.789 – 1.07 0.286 183 1830 all phecode
187.8
Neoplasm of uncertain behavior of male genital
Neoplasm of uncertain behavior of male genital organs
 Neoplasms 0.961 0.734 – 1.26 0.773 57 562 all phecode
189
Cancer of urinary organs (incl. kidney and
Cancer of urinary organs (incl. kidney and bladder)
 Neoplasms 0.998 0.96 – 1.04 0.909 2923 23541 all phecode
189.1 Cancer of kidney and renal pelvis Neoplasms 1.01 0.96 – 1.07 0.642 1450 14437 all phecode
189.11 Malignant neoplasm of kidney, except pelvis Neoplasms 1.02 0.965 – 1.08 0.445 1267 12655 all phecode
189.12 Malignant neoplasm of renal pelvis Neoplasms 0.989 0.865 – 1.13 0.873 237 2347 all phecode
189.2 Cancer of bladder Neoplasms 0.993 0.945 – 1.04 0.787 1783 15224 all phecode
189.21 Malignant neoplasm of bladder Neoplasms 0.981 0.932 – 1.03 0.456 1657 14178 all phecode
189.4 Malignant neoplasm of other urinary organs Neoplasms 1.01 0.932 – 1.09 0.832 678 6586 all phecode
190 Cancer of eye Neoplasms 1 0.835 – 1.2 0.989 138 1374 all phecode
191
Manlignant and unknown neoplasms of brain and
Manlignant and unknown neoplasms of brain and nervous system
 Neoplasms 0.978 0.918 – 1.04 0.498 1078 10771 all phecode
191.1 Cancer of brain and nervous system Neoplasms 0.98 0.907 – 1.06 0.609 706 7052 all phecode
191.11 Cancer of brain Neoplasms 1 0.922 – 1.09 0.953 600 5996 all phecode
193 Thyroid cancer Neoplasms 0.97 0.907 – 1.04 0.377 945 9393 all phecode
194 Cancer of other endocrine glands Neoplasms 0.967 0.887 – 1.05 0.445 579 5759 all phecode
195 Cancer, suspected or other Neoplasms 1 0.984 – 1.03 0.659 16962 26401 all phecode
195.1 Malignant neoplasm, other Neoplasms 1.01 0.985 – 1.03 0.566 16670 26384 all phecode
195.3 Malignant neoplasm of head, face, and neck Neoplasms 0.992 0.932 – 1.06 0.807 1103 9766 all phecode
196 Radiotherapy Neoplasms 1.01 0.969 – 1.06 0.582 2427 17006 all phecode
197 Chemotherapy Neoplasms 1.03 0.994 – 1.06 0.109 4952 23797 all phecode
198 Secondary malignant neoplasm Neoplasms 1.01 0.985 – 1.05 0.342 5801 23481 all phecode
198.1 Secondary malignancy of lymph nodes Neoplasms 1 0.967 – 1.04 0.884 3677 21489 all phecode
198.2 Secondary malignancy of respiratory organs Neoplasms 0.978 0.918 – 1.04 0.495 1072 10334 all phecode
198.3
Secondary malignant neoplasm of digestive
Secondary malignant neoplasm of digestive systems
 Neoplasms 1 0.934 – 1.08 0.931 866 8538 all phecode
198.4 Secondary malignant neoplasm of liver Neoplasms 1.07 0.991 – 1.15 0.0857 767 7558 all phecode
198.5 Secondary malignancy of brain/spine Neoplasms 0.97 0.894 – 1.05 0.473 640 6338 all phecode
198.6 Secondary malignancy of bone Neoplasms 1.05 0.977 – 1.13 0.184 866 8307 all phecode
198.7 Secondary malignant neoplasm of skin Neoplasms 1 0.896 – 1.12 0.963 336 3253 all phecode
199 Neoplasm of uncertain behavior Neoplasms 0.997 0.968 – 1.03 0.831 5693 25767 all phecode
199.4 Neurofibromatosis Neoplasms 1.05 0.846 – 1.31 0.646 88 880 all phecode
200 Myeloproliferative disease Neoplasms 1.01 0.95 – 1.08 0.736 1113 11098 all phecode
200.1 Polycythemia vera Neoplasms 1.02 0.892 – 1.16 0.802 231 2310 all phecode
201 Hodgkin's disease Neoplasms 0.912 0.781 – 1.07 0.245 172 1705 all phecode
202 Cancer of other lymphoid, histiocytic tissue Neoplasms 0.989 0.939 – 1.04 0.688 1559 15571 all phecode
202.2 Non-Hodgkins lymphoma Neoplasms 0.974 0.92 – 1.03 0.365 1329 13268 all phecode
202.21 Nodular lymphoma Neoplasms 0.931 0.861 – 1.01 0.0752 693 6923 all phecode
202.22 Reticulosarcoma Neoplasms 1 0.859 – 1.17 0.965 170 1693 all phecode
202.24 Large cell lymphoma Neoplasms 1.02 0.869 – 1.2 0.802 160 1586 all phecode
204 Leukemia Neoplasms 1 0.927 – 1.09 0.94 689 6876 all phecode
204.1 Lymphoid leukemia Neoplasms 0.933 0.816 – 1.07 0.306 236 2354 all phecode
204.11 Lymphoid leukemia, acute Neoplasms 0.983 0.771 – 1.25 0.887 74 734 all phecode
204.12 Lymphoid leukemia, chronic Neoplasms 0.916 0.785 – 1.07 0.266 173 1724 all phecode
204.2 Myeloid leukemia Neoplasms 1.02 0.898 – 1.16 0.774 265 2633 all phecode
204.21 Myeloid leukemia, acute Neoplasms 0.951 0.802 – 1.13 0.559 153 1516 all phecode
204.22 Myeloid leukemia, chronic Neoplasms 1.06 0.822 – 1.36 0.66 61 610 all phecode
204.4 Multiple myeloma Neoplasms 1.02 0.889 – 1.18 0.76 217 2162 all phecode
208 Benign neoplasm of colon Neoplasms 1.02 0.996 – 1.04 0.114 10303 34953 all phecode
209 Neuroendocrine tumors Neoplasms 1 0.884 – 1.14 0.94 258 2580 all phecode
210 Benign neoplasm of lip, oral cavity, and pharynx Neoplasms 0.986 0.94 – 1.03 0.573 1891 18839 all phecode
211
Benign neoplasm of other parts of digestive
Benign neoplasm of other parts of digestive system
 Neoplasms 0.986 0.961 – 1.01 0.269 7329 36606 all phecode
212
Benign neoplasm of respiratory and
Benign neoplasm of respiratory and intrathoracic organs
 Neoplasms 1.01 0.959 – 1.06 0.787 1843 18412 all phecode
213 Benign neoplasm of bone and articular cartilage Neoplasms 0.938 0.891 – 0.987 0.0133 1677 15527 all phecode
214 Lipoma Neoplasms 1.04 0.982 – 1.1 0.191 1437 14132 all phecode
214.1 Lipoma of skin and subcutaneous tissue Neoplasms 1.06 0.989 – 1.14 0.1 883 8710 all phecode
215
Other benign neoplasm of connective and other
Other benign neoplasm of connective and other soft tissue
 Neoplasms 0.972 0.942 – 1 0.0685 4528 39509 all phecode
216 Benign neoplasm of skin Neoplasms 0.996 0.975 – 1.02 0.697 11528 34919 all phecode
216.1 Screening for malignant neoplasms of the skin Neoplasms 1.02 0.869 – 1.2 0.809 174 1701 all phecode
217 Vascular hamartomas and non-neoplastic nevi Neoplasms 1.02 0.974 – 1.08 0.356 1786 17184 all phecode
217.1 Nevus, non-neoplastic Neoplasms 1.04 0.986 – 1.09 0.162 1679 16116 all phecode
218 Benign neoplasm of uterus Neoplasms 0.966 0.934 – 0.999 0.0451 4301 16661 all phecode
218.1 Uterine leiomyoma Neoplasms 0.948 0.903 – 0.996 0.0333 1835 15733 all phecode
218.2 Other benign neoplasm of uterus Neoplasms 0.963 0.927 – 0.999 0.0451 3403 16447 all phecode
220 Benign neoplasm of ovary Neoplasms 0.979 0.913 – 1.05 0.557 893 8783 all phecode
221 Benign neoplasm of other female genital organs Neoplasms 0.983 0.939 – 1.03 0.484 2042 14248 all phecode
222 Benign neoplasm of male genital organs Neoplasms 0.967 0.909 – 1.03 0.276 1133 10663 all phecode
223
Benign neoplasm of kidney and other urinary
Benign neoplasm of kidney and other urinary organs
 Neoplasms 1.02 0.972 – 1.08 0.389 1801 12657 all phecode
224 Benign neoplasm of eye Neoplasms 0.945 0.873 – 1.02 0.165 691 6752 all phecode
224.1 Benign neoplasm of eye, uveal Neoplasms 0.974 0.894 – 1.06 0.551 595 5773 all phecode
225
Benign neoplasm of brain and other parts of
Benign neoplasm of brain and other parts of nervous system
 Neoplasms 0.973 0.917 – 1.03 0.364 1209 12074 all phecode
225.1
Benign neoplasm of brain, cranial nerves
Benign neoplasm of brain, cranial nerves, meninges
 Neoplasms 0.968 0.905 – 1.03 0.339 947 9454 all phecode
225.2 Benign neoplasm of spinal cord, meninges Neoplasms 1.03 0.916 – 1.17 0.589 289 2890 all phecode
226 Benign neoplasm of thyroid glands Neoplasms 0.99 0.936 – 1.05 0.736 1329 13264 all phecode
227
Benign neoplasm of other endocrine glands and
Benign neoplasm of other endocrine glands and related structures
 Neoplasms 0.972 0.924 – 1.02 0.264 1690 16896 all phecode
227.1 Benign neoplasm of adrenal gland Neoplasms 1.1 0.999 – 1.21 0.0522 467 4644 all phecode
227.2 Benign neoplasm of parathyroid gland Neoplasms 0.952 0.884 – 1.02 0.189 795 7941 all phecode
227.3
Benign neoplasm of pituitary gland and
Benign neoplasm of pituitary gland and craniopharyngeal duct (pouch)
 Neoplasms 0.941 0.853 – 1.04 0.229 435 4350 all phecode
228 Hemangioma and lymphangioma, any site Neoplasms 1.05 1.01 – 1.1 0.0246 2149 20946 all phecode
228.1 Hemangioma of skin and subcutaneous tissue Neoplasms 1.05 0.992 – 1.11 0.0939 1356 13336 all phecode
229 Benign neoplasm of unspecified sites Neoplasms 0.988 0.964 – 1.01 0.351 7767 36615 all phecode
229.1 Benign neoplasm of lymph nodes Neoplasms 0.994 0.966 – 1.02 0.686 5743 34218 all phecode
240 Simple and unspecified goiter Endocrine/metabolic 1 0.94 – 1.07 0.913 1031 9761 all phecode
241 Nontoxic nodular goiter Endocrine/metabolic 0.98 0.943 – 1.02 0.321 2910 22227 all phecode
241.1 Nontoxic uninodular goiter Endocrine/metabolic 0.99 0.947 – 1.03 0.651 2265 19902 all phecode
241.2 Nontoxic multinodular goiter Endocrine/metabolic 0.986 0.931 – 1.04 0.643 1304 12479 all phecode
242 Thyrotoxicosis with or without goiter Endocrine/metabolic 0.968 0.915 – 1.02 0.244 1400 13425 all phecode
242.1 Graves' disease Endocrine/metabolic 0.953 0.87 – 1.04 0.306 515 5068 all phecode
242.2 Toxic multinodular goiter Endocrine/metabolic 1.03 0.851 – 1.25 0.747 124 1224 all phecode
242.3 Exophthalmos Endocrine/metabolic 1.07 0.944 – 1.2 0.305 292 2898 all phecode
242.31 Thyrotoxic exophthalmos Endocrine/metabolic 0.903 0.758 – 1.08 0.251 144 1432 all phecode
244 Hypothyroidism Endocrine/metabolic 0.982 0.958 – 1.01 0.171 8099 32717 all phecode
244.1 Secondary hypothyroidism Endocrine/metabolic 0.964 0.917 – 1.01 0.148 1762 17230 all phecode
244.2 Acquired hypothyroidism Endocrine/metabolic 1.04 0.979 – 1.1 0.209 1261 11982 all phecode
244.4 Hypothyroidism NOS Endocrine/metabolic 0.985 0.96 – 1.01 0.258 7542 32208 all phecode
245 Thyroiditis Endocrine/metabolic 0.989 0.92 – 1.06 0.77 832 7882 all phecode
245.2 Chronic thyroiditis Endocrine/metabolic 0.976 0.901 – 1.06 0.557 686 6517 all phecode
245.21 Chronic lymphocytic thyroiditis Endocrine/metabolic 0.973 0.898 – 1.05 0.503 679 6449 all phecode
246 Other disorders of thyroid Endocrine/metabolic 0.954 0.927 – 0.981 0.00106 6129 30240 all phecode
246.2 Thyroid cyst Endocrine/metabolic 0.912 0.744 – 1.12 0.375 101 960 all phecode
246.7 Abnormal results of function study of thyroid Endocrine/metabolic 0.984 0.918 – 1.05 0.637 886 8696 all phecode
249 Secondary diabetes mellitus Endocrine/metabolic 0.96 0.896 – 1.03 0.248 1150 8340 all phecode
250 Diabetes mellitus Endocrine/metabolic 0.993 0.971 – 1.01 0.505 13947 31815 all phecode
250.1 Type 1 diabetes Endocrine/metabolic 0.953 0.898 – 1.01 0.106 2364 11758 all phecode
250.11 Type 1 diabetes with ketoacidosis Endocrine/metabolic 0.919 0.774 – 1.09 0.33 262 960 all phecode
250.12 Type 1 diabetes with renal manifestations Endocrine/metabolic 0.94 0.835 – 1.06 0.3 551 2686 all phecode
250.13 Type 1 diabetes with ophthalmic manifestations Endocrine/metabolic 0.973 0.873 – 1.08 0.621 784 3018 all phecode
250.14 Type 1 diabetes with neurological manifestations Endocrine/metabolic 1.01 0.903 – 1.13 0.837 638 2675 all phecode
250.15
Diabetes type 1 with peripheral circulatory
Diabetes type 1 with peripheral circulatory disorders
 Endocrine/metabolic 0.902 0.74 – 1.1 0.308 155 850 all phecode
250.2 Type 2 diabetes Endocrine/metabolic 0.979 0.954 – 1 0.0937 9843 29688 all phecode
250.21 Type 2 diabetes with ketoacidosis Endocrine/metabolic 0.907 0.777 – 1.06 0.216 282 1327 all phecode
250.22 Type 2 diabetes with renal manifestations Endocrine/metabolic 0.974 0.923 – 1.03 0.341 1941 13510 all phecode
250.23 Type 2 diabetes with ophthalmic manifestations Endocrine/metabolic 0.983 0.921 – 1.05 0.602 1643 9668 all phecode
250.24 Type 2 diabetes with neurological manifestations Endocrine/metabolic 0.986 0.939 – 1.04 0.564 2557 16502 all phecode
250.25
Diabetes type 2 with peripheral circulatory
Diabetes type 2 with peripheral circulatory disorders
 Endocrine/metabolic 1.04 0.959 – 1.13 0.346 860 6143 all phecode
250.3 Insulin pump user Endocrine/metabolic 0.976 0.935 – 1.02 0.272 3496 20809 all phecode
250.4 Abnormal glucose Endocrine/metabolic 1.02 0.994 – 1.05 0.123 8385 30645 all phecode
250.41 Impaired fasting glucose Endocrine/metabolic 1.02 0.973 – 1.08 0.358 1870 15861 all phecode
250.42 Other abnormal glucose Endocrine/metabolic 1.02 0.997 – 1.05 0.0843 7553 30071 all phecode
250.5 Glycosuria or Acetonuria Endocrine/metabolic 0.899 0.744 – 1.09 0.27 136 1067 all phecode
250.6 Polyneuropathy in diabetes Endocrine/metabolic 0.968 0.916 – 1.02 0.242 2132 13390 all phecode
250.7 Diabetic retinopathy Endocrine/metabolic 0.977 0.925 – 1.03 0.418 1691 10517 all phecode
251 Other disorders of pancreatic internal secretion Endocrine/metabolic 1.02 0.951 – 1.09 0.631 991 8469 all phecode
251.1 Hypoglycemia Endocrine/metabolic 1.04 0.966 – 1.11 0.324 1207 8570 all phecode
252 Disorders of parathyroid gland Endocrine/metabolic 1.01 0.964 – 1.05 0.769 2282 22119 all phecode
252.1 Hyperparathyroidism Endocrine/metabolic 1 0.959 – 1.05 0.889 2088 20335 all phecode
252.2 Hypoparathyroidism Endocrine/metabolic 1.03 0.939 – 1.13 0.532 508 5073 all phecode
253
Disorders of the pituitary gland and its
Disorders of the pituitary gland and its hypothalamic control
 Endocrine/metabolic 1.01 0.943 – 1.08 0.751 859 8544 all phecode
253.1 Pituitary hyperfunction Endocrine/metabolic 0.939 0.826 – 1.07 0.337 263 2621 all phecode
253.11 Acromegaly and gigantism Endocrine/metabolic 0.996 0.797 – 1.24 0.971 83 826 all phecode
253.2 Pituitary hypofunction Endocrine/metabolic 0.99 0.863 – 1.13 0.882 226 2250 all phecode
253.3 Diabetes insipidus Endocrine/metabolic 0.871 0.695 – 1.09 0.231 86 860 all phecode
253.4 Anterior pituitary disorders Endocrine/metabolic 0.96 0.795 – 1.16 0.667 121 1209 all phecode
253.7 Other disorders of neurohypophysis Endocrine/metabolic 1.24 1.03 – 1.49 0.0261 108 1080 all phecode
255 Disorders of adrenal glands Endocrine/metabolic 0.96 0.91 – 1.01 0.137 1506 14869 all phecode
255.1 Adrenal hyperfunction Endocrine/metabolic 0.967 0.868 – 1.08 0.544 373 3730 all phecode
255.11 Cushing's syndrome Endocrine/metabolic 0.987 0.847 – 1.15 0.871 183 1830 all phecode
255.12 Hyperaldosteronism Endocrine/metabolic 1.1 0.925 – 1.32 0.274 135 1350 all phecode
255.2 Adrenal hypofunction Endocrine/metabolic 0.955 0.88 – 1.04 0.271 626 6239 all phecode
255.21 Glucocorticoid deficiency Endocrine/metabolic 0.946 0.869 – 1.03 0.197 596 5941 all phecode
256 Ovarian dysfunction Endocrine/metabolic 0.972 0.914 – 1.03 0.373 1146 10513 all phecode
256.4 Polycystic ovaries Endocrine/metabolic 0.985 0.912 – 1.06 0.697 742 7128 all phecode
257 Testicular dysfunction Endocrine/metabolic 1.01 0.947 – 1.08 0.742 1015 9238 all phecode
257.1 Testicular hypofunction Endocrine/metabolic 1.02 0.955 – 1.09 0.541 983 8933 all phecode
258 Iatrogenic endocrine disorders Endocrine/metabolic 0.971 0.779 – 1.21 0.791 91 910 all phecode
258.1 Postablative ovarian failure Endocrine/metabolic 0.891 0.733 – 1.08 0.249 109 1090 all phecode
259 Other endocrine disorders Endocrine/metabolic 0.989 0.927 – 1.06 0.737 1038 10259 all phecode
260 Protein-calorie malnutrition Endocrine/metabolic 1.02 0.983 – 1.06 0.283 2880 26812 all phecode
260.1 Cachexia Endocrine/metabolic 1.08 0.957 – 1.21 0.219 292 2911 all phecode
260.2 severe protein-calorie malnutrition Endocrine/metabolic 1.03 0.977 – 1.08 0.284 1691 16847 all phecode
260.22 Nutritional marasmus Endocrine/metabolic 1.03 0.95 – 1.12 0.447 614 6140 all phecode
260.3 Adult failure to thrive Endocrine/metabolic 1.04 0.96 – 1.13 0.325 629 6236 all phecode
260.6 Anorexia Endocrine/metabolic 1.07 0.995 – 1.15 0.068 868 8591 all phecode
260.7 Polyphagia Endocrine/metabolic 1.13 0.866 – 1.46 0.378 65 643 all phecode
261 Vitamin deficiency Endocrine/metabolic 1.01 0.986 – 1.04 0.396 7718 35203 all phecode
261.1 Vitamin A deficiency Endocrine/metabolic 0.994 0.777 – 1.27 0.963 69 690 all phecode
261.2 Vitamin B-complex deficiencies Endocrine/metabolic 1 0.933 – 1.07 0.978 857 8405 all phecode
261.4 Vitamin D deficiency Endocrine/metabolic 1.01 0.988 – 1.04 0.295 7255 35225 all phecode
261.41 Rickets or osteomalacia Endocrine/metabolic 1.03 0.772 – 1.36 0.862 52 511 all phecode
262 Mineral deficiency NEC Endocrine/metabolic 1.01 0.954 – 1.08 0.658 1182 11676 all phecode
263 Other nutritional deficiency Endocrine/metabolic 1 0.95 – 1.05 0.985 1651 15788 all phecode
264 Lack of normal physiological development Endocrine/metabolic 1.02 0.894 – 1.17 0.724 239 2301 all phecode
264.2 Failure to thrive (childhood) Endocrine/metabolic 1.05 0.866 – 1.26 0.642 122 1220 all phecode
264.9
Lack of normal physiological development
Lack of normal physiological development, unspecified
 Endocrine/metabolic 1.01 0.799 – 1.26 0.962 81 772 all phecode
269 Proteinuria Endocrine/metabolic 1.04 0.988 – 1.09 0.137 1694 13981 all phecode
270
Disorders of protein plasma/amino-acid
Disorders of protein plasma/amino-acid transport and metabolism
 Endocrine/metabolic 1.01 0.942 – 1.08 0.841 967 9575 all phecode
270.1 Disturbances of amino-acid transport Endocrine/metabolic 0.892 0.761 – 1.05 0.161 170 1697 all phecode
270.11
Disturbances of sulphur-bearing amino-acid
Disturbances of sulphur-bearing amino-acid metabolism
 Endocrine/metabolic 0.838 0.698 – 1.01 0.0585 134 1334 all phecode
270.2 Disorders of amino-acid metabolism Endocrine/metabolic 0.823 0.666 – 1.02 0.0705 96 954 all phecode
270.3 Disorders of plasma protein metabolism Endocrine/metabolic 1.06 0.981 – 1.14 0.146 737 7303 all phecode
270.32 Paraproteinemia Endocrine/metabolic 1.03 0.93 – 1.15 0.537 384 3781 all phecode
270.33 Amyloidosis Endocrine/metabolic 1.09 0.859 – 1.37 0.49 71 695 all phecode
270.34 Alpha-1-antitrypsin deficiency Endocrine/metabolic 1.07 0.842 – 1.35 0.598 69 690 all phecode
270.38
Other specified disorders of plasma protein
Other specified disorders of plasma protein metabolism
 Endocrine/metabolic 1.07 0.95 – 1.21 0.257 299 2984 all phecode
271
Disorders of carbohydrate transport and
Disorders of carbohydrate transport and metabolism
 Endocrine/metabolic 1.03 0.986 – 1.07 0.208 2907 28132 all phecode
271.3
Intestinal disaccharidase deficiencies and
Intestinal disaccharidase deficiencies and disaccharide malabsorption
 Endocrine/metabolic 1.03 0.989 – 1.07 0.162 2827 27425 all phecode
271.9
Other disorders of carbohydrate transport and
Other disorders of carbohydrate transport and metabolism
 Endocrine/metabolic 0.902 0.743 – 1.1 0.299 102 1007 all phecode
272 Disorders of lipoid metabolism Endocrine/metabolic 1.34 1.32 – 1.37 8.33e-163 18881 26670 all phecode
272.1 Hyperlipidemia Endocrine/metabolic 1.35 1.32 – 1.37 7.2e-164 18843 26654 all phecode
272.11 Hypercholesterolemia Endocrine/metabolic 1.47 1.43 – 1.52 1.68e-123 5928 21600 all phecode
272.12 Hyperglyceridemia Endocrine/metabolic 1.2 1.14 – 1.28 2.83e-10 1360 11837 all phecode
272.13 Mixed hyperlipidemia Endocrine/metabolic 1.39 1.34 – 1.45 5.7e-60 3538 18449 all phecode
272.9 Unspecified disorder of lipoid metabolism Endocrine/metabolic 1.19 1.06 – 1.34 0.00392 313 3011 all phecode
274 Gout and other crystal arthropathies Endocrine/metabolic 1 0.961 – 1.04 0.929 2524 22729 all phecode
274.1 Gout Endocrine/metabolic 1.01 0.967 – 1.05 0.689 2409 21991 all phecode
274.11 Gouty arthropathy Endocrine/metabolic 1.01 0.95 – 1.08 0.709 1082 10576 all phecode
274.2 Crystal arthropathies Endocrine/metabolic 1.02 0.88 – 1.19 0.768 195 1890 all phecode
274.21 Chondrocalcinosis Endocrine/metabolic 1.02 0.872 – 1.19 0.818 183 1772 all phecode
275 Disorders of mineral metabolism Endocrine/metabolic 0.987 0.956 – 1.02 0.417 4357 37091 all phecode
275.1 Disorders of iron metabolism Hematopoietic 0.836 0.728 – 0.961 0.0118 218 2180 all phecode
275.11 Hereditary hemochromatosis Hematopoietic 0.767 0.63 – 0.934 0.00823 99 990 all phecode
275.2 Disorders of copper metabolism Endocrine/metabolic 0.99 0.764 – 1.28 0.937 62 614 all phecode
275.3 Disorders of magnesium metabolism Endocrine/metabolic 1.02 0.955 – 1.08 0.631 1154 11504 all phecode
275.5 Disorders of calcium/phosphorus metabolism Endocrine/metabolic 0.978 0.943 – 1.01 0.222 3369 31544 all phecode
275.51 Hypocalcemia Endocrine/metabolic 0.95 0.886 – 1.02 0.142 898 8969 all phecode
275.53 Disorders of phosphorus metabolism Endocrine/metabolic 0.964 0.912 – 1.02 0.191 1366 13634 all phecode
275.6 Hypercalcemia Endocrine/metabolic 1.01 0.958 – 1.07 0.666 1468 14183 all phecode
276
Disorders of fluid, electrolyte, and acid-base
Disorders of fluid, electrolyte, and acid-base balance
 Endocrine/metabolic 1.02 0.992 – 1.04 0.207 9238 37046 all phecode
276.1 Electrolyte imbalance Endocrine/metabolic 1.01 0.985 – 1.04 0.366 6352 34366 all phecode
276.11 Hyperosmolality and/or hypernatremia Endocrine/metabolic 0.979 0.897 – 1.07 0.629 550 5434 all phecode
276.12 Hyposmolality and/or hyponatremia Endocrine/metabolic 1.01 0.97 – 1.05 0.591 2514 23219 all phecode
276.13 Hyperpotassemia Endocrine/metabolic 0.997 0.96 – 1.04 0.897 2992 25216 all phecode
276.14 Hypopotassemia Endocrine/metabolic 1.02 0.972 – 1.06 0.463 2148 20909 all phecode
276.4 Acid-base balance disorder Endocrine/metabolic 1.01 0.966 – 1.06 0.631 2086 20332 all phecode
276.41 Acidosis Endocrine/metabolic 1 0.956 – 1.05 0.881 1788 17572 all phecode
276.42 Alkalosis Endocrine/metabolic 1.09 0.99 – 1.2 0.0802 476 4741 all phecode
276.5 Hypovolemia Endocrine/metabolic 1.02 0.99 – 1.05 0.19 4574 34527 all phecode
276.6 Fluid overload Endocrine/metabolic 0.97 0.917 – 1.03 0.284 1384 13211 all phecode
276.8 Polydipsia Endocrine/metabolic 1.2 0.993 – 1.45 0.0593 124 1240 all phecode
277 Other disorders of metabolism Endocrine/metabolic 0.999 0.967 – 1.03 0.975 4112 35070 all phecode
277.2
Other disorders of purine and pyrimidine
Other disorders of purine and pyrimidine metabolism
 Endocrine/metabolic 1.03 0.927 – 1.15 0.575 403 3991 all phecode
277.4 Disorders of bilirubin excretion Endocrine/metabolic 0.995 0.922 – 1.07 0.905 720 7161 all phecode
277.5 Other disorders of lipoid metabolism Endocrine/metabolic 0.939 0.878 – 1.01 0.0705 936 9270 all phecode
277.51 Lipoprotein disorders Endocrine/metabolic 0.932 0.865 – 1 0.0662 773 7668 all phecode
277.7 Dysmetabolic syndrome X Endocrine/metabolic 1.03 0.962 – 1.1 0.394 916 8359 all phecode
278 Overweight, obesity and other hyperalimentation Endocrine/metabolic 0.981 0.963 – 0.999 0.0435 19419 27331 all phecode
278.1 Obesity Endocrine/metabolic 0.975 0.956 – 0.994 0.011 17129 27321 all phecode
278.11 Morbid obesity Endocrine/metabolic 0.966 0.942 – 0.99 0.00629 8280 27172 all phecode
278.3 Localized adiposity Endocrine/metabolic 0.876 0.781 – 0.981 0.0224 324 3228 all phecode
278.4 Abnormal weight gain Endocrine/metabolic 0.978 0.934 – 1.02 0.35 2104 17411 all phecode
279 Disorders involving the immune mechanism Endocrine/metabolic 0.96 0.924 – 0.998 0.0377 2934 28612 all phecode
279.1 Immunity deficiency Endocrine/metabolic 0.957 0.9 – 1.02 0.163 1161 11571 all phecode
279.11 Deficiency of humoral immunity Endocrine/metabolic 1 0.894 – 1.12 0.974 330 3278 all phecode
279.2 Autoimmune disease NEC Endocrine/metabolic 0.931 0.864 – 1 0.0626 754 7516 all phecode
279.7 Other immunological findings Endocrine/metabolic 1.01 0.976 – 1.04 0.678 4885 36552 all phecode
279.8
Other specified disorders involving the immune
Other specified disorders involving the immune mechanism
 Endocrine/metabolic 0.934 0.86 – 1.02 0.11 601 5988 all phecode
280 Iron deficiency anemias Hematopoietic 1.03 0.999 – 1.06 0.057 4626 30873 all phecode
280.1
Iron deficiency anemias, unspecified or not due
Iron deficiency anemias, unspecified or not due to blood loss
 Hematopoietic 1.03 0.994 – 1.06 0.118 4484 30649 all phecode
280.2
Iron deficiency anemia secondary to blood loss
Iron deficiency anemia secondary to blood loss (chronic)
 Hematopoietic 1.01 0.961 – 1.06 0.69 1771 17196 all phecode
281 Other deficiency anemia Hematopoietic 0.998 0.911 – 1.09 0.961 519 5120 all phecode
281.1 Megaloblastic anemia Hematopoietic 0.96 0.844 – 1.09 0.528 253 2497 all phecode
281.11 Pernicious anemia Hematopoietic 0.915 0.755 – 1.11 0.369 114 1108 all phecode
281.12 Other vitamin B12 deficiency anemia Hematopoietic 0.959 0.827 – 1.11 0.584 187 1817 all phecode
281.9 Deficiency anemias Hematopoietic 1.06 0.931 – 1.2 0.397 285 2830 all phecode
282 Hereditary hemolytic anemias Hematopoietic 0.962 0.857 – 1.08 0.516 323 3188 all phecode
282.8 Other hemoglobinopathies Hematopoietic 0.879 0.762 – 1.01 0.0757 216 2113 all phecode
282.9 Other hereditary hemolytic anemias Hematopoietic 1.04 0.896 – 1.21 0.612 192 1920 all phecode
283 Acquired hemolytic anemias Hematopoietic 1.06 0.894 – 1.26 0.499 155 1550 all phecode
283.1 Autoimmune hemolytic anemias Hematopoietic 1.22 0.935 – 1.58 0.143 64 633 all phecode
284 Aplastic anemia Hematopoietic 1.04 0.964 – 1.13 0.291 697 6943 all phecode
284.1 Pancytopenia Hematopoietic 1.05 0.962 – 1.14 0.288 612 6100 all phecode
285 Other anemias Hematopoietic 1.01 0.992 – 1.04 0.218 11794 33591 all phecode
285.1 Acute posthemorrhagic anemia Hematopoietic 1.03 0.99 – 1.07 0.152 3325 27709 all phecode
285.2 Anemia of chronic disease Hematopoietic 1.01 0.969 – 1.06 0.528 2055 19939 all phecode
285.21 Anemia in chronic kidney disease Hematopoietic 0.976 0.911 – 1.04 0.479 932 9106 all phecode
285.22 Anemia in neoplastic disease Hematopoietic 1.03 0.947 – 1.11 0.53 690 6892 all phecode
286 Coagulation defects Hematopoietic 1.01 0.972 – 1.04 0.759 3844 33384 all phecode
286.1 Congenital coagulation defects Hematopoietic 0.926 0.812 – 1.06 0.251 250 2466 all phecode
286.11 Von willebrand's disease Hematopoietic 1.03 0.819 – 1.29 0.806 83 822 all phecode
286.12
Congenital deficiency of other clotting factors
Congenital deficiency of other clotting factors (including factor VII)
 Hematopoietic 0.892 0.744 – 1.07 0.221 126 1260 all phecode
286.2
Encounter for long-term (current) use of
Encounter for long-term (current) use of anticoagulants
 Hematopoietic 1.02 0.983 – 1.06 0.296 3354 25918 all phecode
286.3
Coagulation defects complicating pregnancy or
Coagulation defects complicating pregnancy or postpartum
 Hematopoietic 0.739 0.602 – 0.907 0.0038 97 962 all phecode
286.4 Acquired coagulation factor deficiency Hematopoietic 1 0.882 – 1.14 0.954 254 2529 all phecode
286.5
Hemorrhagic disorder due to intrinsic
Hemorrhagic disorder due to intrinsic circulating anticoagulants
 Hematopoietic 1.05 0.881 – 1.25 0.582 132 1294 all phecode
286.6 Defibrination syndrome Hematopoietic 1.02 0.981 – 1.06 0.311 2579 25377 all phecode
286.7 Other and unspecified coagulation defects Hematopoietic 1.01 0.969 – 1.04 0.752 3014 29294 all phecode
286.8 Hypercoagulable state Hematopoietic 1.01 0.94 – 1.08 0.822 846 8437 all phecode
286.81 Primary hypercoagulable state Hematopoietic 1 0.933 – 1.08 0.941 813 8111 all phecode
286.9 Abnormal coagulation profile Hematopoietic 1.02 0.956 – 1.08 0.614 1182 11487 all phecode
287 Purpura and other hemorrhagic conditions Hematopoietic 1.04 1 – 1.08 0.032 3288 28474 all phecode
287.1 Spontaneous ecchymoses Hematopoietic 0.963 0.836 – 1.11 0.6 211 2094 all phecode
287.3 Thrombocytopenia Hematopoietic 1.04 1 – 1.08 0.031 2938 26323 all phecode
287.31 Primary thrombocytopenia Hematopoietic 1.02 0.935 – 1.11 0.692 601 5994 all phecode
287.32 Secondary thrombocytopenia Hematopoietic 1.04 0.956 – 1.14 0.343 569 5686 all phecode
287.4 Qualitative platelet defects Hematopoietic 1.14 0.943 – 1.37 0.179 112 1120 all phecode
288 Diseases of white blood cells Hematopoietic 0.988 0.959 – 1.02 0.435 4886 36527 all phecode
288.1 Decreased white blood cell count Hematopoietic 1.01 0.955 – 1.06 0.816 1599 15951 all phecode
288.11 Neutropenia Hematopoietic 0.985 0.925 – 1.05 0.643 1106 11041 all phecode
288.2 Elevated white blood cell count Hematopoietic 0.978 0.947 – 1.01 0.181 4082 35079 all phecode
288.3 Eosinophilia Hematopoietic 0.908 0.784 – 1.05 0.193 187 1866 all phecode
289 Other diseases of blood and blood-forming organs Hematopoietic 0.965 0.919 – 1.01 0.161 1757 17434 all phecode
289.3
Personal history of diseases of blood and
Personal history of diseases of blood and blood-forming organs
 Hematopoietic 1.01 0.944 – 1.08 0.757 918 9087 all phecode
289.4 Lymphadenitis Hematopoietic 0.981 0.949 – 1.01 0.273 3888 34715 all phecode
289.5 Diseases of spleen Hematopoietic 1.01 0.912 – 1.13 0.804 393 3913 all phecode
289.8 Polycythemia, secondary Hematopoietic 0.909 0.801 – 1.03 0.14 255 2550 all phecode
289.9 Abnormality of red blood cells Hematopoietic 0.95 0.857 – 1.05 0.334 385 3813 all phecode
290
Delirium dementia and amnestic and other
Delirium dementia and amnestic and other cognitive disorders
 Mental Disorders 1.05 0.987 – 1.11 0.129 1318 11547 all phecode
290.1 Dementias Mental Disorders 1.09 1 – 1.2 0.0449 541 4910 all phecode
290.11 Alzheimer's disease Mental Disorders 1.04 0.882 – 1.24 0.615 151 1389 all phecode
290.12 Dementia with cerebral degenerations Mental Disorders 0.891 0.717 – 1.11 0.296 88 846 all phecode
290.13 Senile dementia Mental Disorders 1.08 0.967 – 1.21 0.171 340 3078 all phecode
290.16 Vascular dementia Mental Disorders 1.05 0.829 – 1.32 0.708 81 777 all phecode
290.2 Delirium due to conditions classified elsewhere Mental Disorders 1.01 0.936 – 1.09 0.815 750 7358 all phecode
290.3
Other persistent mental disorders due to
Other persistent mental disorders due to conditions classified elsewhere
 Mental Disorders 1.06 0.991 – 1.14 0.0876 886 8618 all phecode
291
Other specified nonpsychotic and/or transient
Other specified nonpsychotic and/or transient mental disorders
 Mental Disorders 0.998 0.957 – 1.04 0.91 2550 24810 all phecode
291.1
Transient mental disorders due to conditions
Transient mental disorders due to conditions classified elsewhere
 Mental Disorders 0.994 0.857 – 1.15 0.941 175 1750 all phecode
291.4
Specific nonpsychotic mental disorders due to
Specific nonpsychotic mental disorders due to brain damage
 Mental Disorders 1.02 0.926 – 1.12 0.733 484 4807 all phecode
291.8 Alteration of consciousness Mental Disorders 1 0.956 – 1.05 0.957 2036 19974 all phecode
292 Neurological disorders Mental Disorders 0.992 0.965 – 1.02 0.581 5733 38553 all phecode
292.1 Aphasia/speech disturbance Mental Disorders 0.974 0.93 – 1.02 0.274 2013 19867 all phecode
292.11 Aphasia Mental Disorders 0.984 0.908 – 1.07 0.704 664 6581 all phecode
292.12 Symbolic dysfunction Mental Disorders 0.918 0.793 – 1.06 0.251 200 1988 all phecode
292.2 Mild cognitive impairment Mental Disorders 1.07 0.963 – 1.19 0.206 389 3731 all phecode
292.3 Memory loss Mental Disorders 1.05 1 – 1.1 0.048 1922 18158 all phecode
292.4 Altered mental status Mental Disorders 0.988 0.947 – 1.03 0.567 2454 22725 all phecode
292.5 Transient alteration of awareness Mental Disorders 0.966 0.875 – 1.07 0.503 430 4285 all phecode
292.6 Hallucinations Mental Disorders 0.87 0.76 – 0.997 0.0449 217 2147 all phecode
293 Symptoms involving head and neck Mental Disorders 0.991 0.895 – 1.1 0.862 414 4127 all phecode
293.1
Swelling, mass, or lump in head and neck
Swelling, mass, or lump in head and neck [Space-occupying lesion, intracranial NOS]
 Mental Disorders 1 0.973 – 1.04 0.784 4417 38609 all phecode
295 Schizophrenia and other psychotic disorders Mental Disorders 0.962 0.896 – 1.03 0.277 885 8229 all phecode
295.1 Schizophrenia Mental Disorders 0.934 0.779 – 1.12 0.462 138 1339 all phecode
295.2 Paranoid disorders Mental Disorders 0.799 0.658 – 0.97 0.0235 118 1079 all phecode
295.3 Psychosis Mental Disorders 0.977 0.903 – 1.06 0.562 716 6694 all phecode
296 Mood disorders Mental Disorders 1.01 0.988 – 1.03 0.4 15356 20858 all phecode
296.1 Bipolar Mental Disorders 0.996 0.939 – 1.06 0.888 1301 11264 all phecode
296.2 Depression Mental Disorders 1.01 0.988 – 1.03 0.368 14833 20856 all phecode
296.22 Major depressive disorder Mental Disorders 1.01 0.987 – 1.03 0.432 13850 20853 all phecode
297 Suicidal ideation or attempt Mental Disorders 0.985 0.92 – 1.05 0.666 985 9050 all phecode
297.1 Suicidal ideation Mental Disorders 0.991 0.918 – 1.07 0.811 788 7310 all phecode
297.2 Suicide or self-inflicted injury Mental Disorders 1.04 0.919 – 1.18 0.528 285 2654 all phecode
300 Anxiety disorders Mental Disorders 1.01 0.991 – 1.03 0.245 15419 20850 all phecode
300.1 Anxiety disorder Mental Disorders 1.01 0.99 – 1.03 0.301 14517 20855 all phecode
300.11 Generalized anxiety disorder Mental Disorders 0.996 0.965 – 1.03 0.792 5546 20512 all phecode
300.12 Agorophobia, social phobia, and panic disorder Mental Disorders 0.996 0.939 – 1.06 0.902 1360 11377 all phecode
300.13 Phobia Mental Disorders 0.989 0.925 – 1.06 0.736 1051 9542 all phecode
300.3 Obsessive-compulsive disorders Mental Disorders 0.938 0.834 – 1.06 0.291 328 3018 all phecode
300.4 Dysthymic disorder Mental Disorders 1.01 0.966 – 1.05 0.669 2420 16552 all phecode
300.8 Acute reaction to stress Mental Disorders 0.971 0.884 – 1.07 0.545 504 4825 all phecode
300.9 Posttraumatic stress disorder Mental Disorders 0.999 0.928 – 1.07 0.974 843 7909 all phecode
301 Personality disorders Mental Disorders 1.01 0.921 – 1.12 0.766 477 4539 all phecode
301.2 Antisocial/borderline personality disorder Mental Disorders 1.08 0.939 – 1.23 0.292 254 2393 all phecode
302 Sexual and gender identity disorders Mental Disorders 0.987 0.951 – 1.03 0.507 3700 13808 all phecode
302.1 Decreased libido Mental Disorders 0.927 0.838 – 1.02 0.137 447 4331 all phecode
303 Psychogenic and somatoform disorders Mental Disorders 1.02 0.994 – 1.05 0.118 6808 20043 all phecode
303.1 Dissociative disorder Mental Disorders 0.913 0.776 – 1.07 0.272 161 1573 all phecode
303.3 Psychogenic disorder Mental Disorders 1.02 0.99 – 1.05 0.198 6487 19888 all phecode
303.31
Gastrointestinal malfunction arising from
Gastrointestinal malfunction arising from mental factors
 Mental Disorders 0.94 0.853 – 1.04 0.21 471 4623 all phecode
303.4 Somatoform disorder Mental Disorders 1.02 0.964 – 1.09 0.447 1177 11180 all phecode
304 Adjustment reaction Mental Disorders 1 0.97 – 1.04 0.814 3888 20475 all phecode
305.2 Eating disorder Mental Disorders 0.934 0.87 – 1 0.0571 901 8329 all phecode
306 Other mental disorder Mental Disorders 0.975 0.927 – 1.03 0.324 1815 14133 all phecode
306.1 Mental disorders durring/after pregnancy Mental Disorders 1.06 0.971 – 1.16 0.187 587 3527 all phecode
306.9 Tension headache Mental Disorders 0.952 0.882 – 1.03 0.201 753 7277 all phecode
312 Conduct disorders Mental Disorders 0.972 0.856 – 1.1 0.663 254 2501 all phecode
312.3 Impulse control disorder Mental Disorders 0.879 0.696 – 1.11 0.279 74 736 all phecode
313 Pervasive developmental disorders Mental Disorders 1.01 0.955 – 1.06 0.808 1571 14633 all phecode
313.1 Attention deficit hyperactivity disorder Mental Disorders 0.993 0.938 – 1.05 0.797 1392 13190 all phecode
313.2 Tics and stuttering Mental Disorders 1.17 0.927 – 1.47 0.187 77 770 all phecode
313.3 Autism Mental Disorders 1.09 0.84 – 1.41 0.518 64 621 all phecode
315 Develomental delays and disorders Mental Disorders 1.04 0.958 – 1.12 0.375 684 6788 all phecode
315.1 Learning disorder Mental Disorders 1.04 0.837 – 1.3 0.71 87 860 all phecode
315.2 Speech and language disorder Mental Disorders 1.1 0.961 – 1.25 0.171 254 2539 all phecode
316 Substance addiction and disorders Mental Disorders 1 0.967 – 1.04 0.972 3682 32680 all phecode
316.1 Polyneuropathy due to drugs Mental Disorders 1.01 0.927 – 1.09 0.881 634 6331 all phecode
317 Alcohol-related disorders Mental Disorders 1.03 0.984 – 1.07 0.239 2525 22920 all phecode
317.1 Alcoholism Mental Disorders 1.02 0.971 – 1.07 0.474 1986 19339 all phecode
317.11 Alcoholic liver damage Mental Disorders 0.991 0.895 – 1.1 0.86 408 4080 all phecode
318 Tobacco use disorder Mental Disorders 1.02 0.996 – 1.04 0.112 8622 34842 all phecode
320 Meningitis Neurological 1.04 0.936 – 1.15 0.475 382 3820 all phecode
323 Encephalitis Neurological 1.01 0.872 – 1.17 0.882 181 1809 all phecode
323.8 Encephalitis, non-infectious Neurological 0.983 0.838 – 1.15 0.834 153 1527 all phecode
324 Other CNS infection and poliomyelitis Neurological 0.995 0.881 – 1.12 0.931 288 2880 all phecode
325
Phlebitis and thrombophlebitis of intracranial
Phlebitis and thrombophlebitis of intracranial venous sinuses
 Neurological 0.877 0.66 – 1.16 0.365 53 530 all phecode
327 Sleep disorders Neurological 0.998 0.978 – 1.02 0.808 14941 31602 all phecode
327.1 Hypersomnia Neurological 1.01 0.963 – 1.06 0.729 2061 19110 all phecode
327.3 Sleep apnea Neurological 1 0.981 – 1.03 0.802 10909 31304 all phecode
327.31 Central/nonobstroctive sleep apnea Neurological 0.978 0.892 – 1.07 0.636 492 4784 all phecode
327.32 Obstructive sleep apnea Neurological 1 0.977 – 1.03 0.94 8744 30530 all phecode
327.4 Insomnia Neurological 0.99 0.961 – 1.02 0.478 5524 30960 all phecode
327.41 Organic or persistent insomnia Neurological 0.987 0.931 – 1.05 0.662 1265 12120 all phecode
327.5 Parasomnia Neurological 0.939 0.863 – 1.02 0.149 604 5913 all phecode
327.6 Circadian rhythm sleep disorder Neurological 0.849 0.746 – 0.965 0.0125 274 2666 all phecode
327.7 Sleep related movement disorders Neurological 0.943 0.898 – 0.99 0.0178 1786 17323 all phecode
327.71 Restless legs syndrome Neurological 0.926 0.879 – 0.976 0.00393 1570 15360 all phecode
327.72 Sleep related leg cramps Neurological 0.992 0.797 – 1.24 0.944 83 822 all phecode
331 Other cerebral degenerations Neurological 1.02 0.947 – 1.1 0.574 717 7024 all phecode
331.1 Hydrocephalus Neurological 0.987 0.873 – 1.12 0.831 284 2836 all phecode
331.9 Cerebral degeneration, unspecified Neurological 1.01 0.913 – 1.12 0.854 419 4026 all phecode
332 Parkinson's disease Neurological 0.91 0.822 – 1.01 0.0689 415 4128 all phecode
333
Extrapyramidal disease and abnormal movement
Extrapyramidal disease and abnormal movement disorders
 Neurological 0.965 0.929 – 1 0.0742 2868 26583 all phecode
333.1 Essential tremor Neurological 0.983 0.911 – 1.06 0.661 725 7163 all phecode
333.2 Myoclonus Neurological 1.16 0.984 – 1.37 0.0758 159 1590 all phecode
333.4 Torsion dystonia Neurological 1.03 0.92 – 1.15 0.622 352 3504 all phecode
333.8 Other degenerative diseases of the basal ganglia Neurological 1 0.802 – 1.26 0.974 89 890 all phecode
334 Degenerative disease of the spinal cord Neurological 0.957 0.898 – 1.02 0.178 1058 10562 all phecode
334.1 Spinocerebellar disease Neurological 0.706 0.551 – 0.904 0.00587 79 790 all phecode
334.2 Anterior horn cell disease Neurological 0.803 0.66 – 0.978 0.0291 110 1080 all phecode
334.21 Amyotrophic Lateral Sclerosis Neurological 0.697 0.548 – 0.886 0.00323 71 693 all phecode
335 Multiple sclerosis Neurological 1.01 0.913 – 1.12 0.811 396 3951 all phecode
337 Disorders of the autonomic nervous system Neurological 0.954 0.887 – 1.03 0.208 808 7413 all phecode
337.1 Peripheral autonomic neuropathy Neurological 0.964 0.863 – 1.08 0.515 370 3164 all phecode
338 Pain Neurological 1.01 0.995 – 1.03 0.144 20346 26417 all phecode
338.1 Acute pain Neurological 1.01 0.991 – 1.03 0.283 15582 26313 all phecode
338.2 Chronic pain Neurological 1.02 0.993 – 1.04 0.172 10994 26368 all phecode
339 Other headache syndromes Neurological 1 0.977 – 1.02 0.96 9242 34658 all phecode
340 Migraine Neurological 0.991 0.964 – 1.02 0.523 6708 30587 all phecode
340.1 Migrain with aura Neurological 1.01 0.978 – 1.05 0.451 3624 23684 all phecode
341
Other demyelinating diseases of central nervous
Other demyelinating diseases of central nervous system
 Neurological 0.945 0.789 – 1.13 0.54 133 1330 all phecode
342 Hemiplegia Neurological 0.969 0.881 – 1.07 0.514 464 4607 all phecode
343 Infantile cerebral palsy Neurological 1.11 0.892 – 1.39 0.343 85 847 all phecode
344 Other paralytic syndromes Neurological 1.02 0.945 – 1.11 0.573 682 6808 all phecode
345 Epilepsy, recurrent seizures, convulsions Neurological 0.953 0.914 – 0.993 0.0212 2553 25307 all phecode
345.1 Epilepsy Neurological 0.898 0.833 – 0.968 0.00495 747 7465 all phecode
345.11 Generalized convulsive epilepsy Neurological 0.916 0.8 – 1.05 0.198 233 2330 all phecode
345.12 Partial epilepsy Neurological 0.91 0.833 – 0.995 0.0383 534 5335 all phecode
345.3 Convulsions Neurological 0.949 0.909 – 0.99 0.0152 2396 23796 all phecode
346
Abnormal findings on study of brain and/or
Abnormal findings on study of brain and/or nervous system
 Neurological 0.941 0.808 – 1.1 0.437 183 1824 all phecode
346.1
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of skull and head
 Neurological 0.966 0.915 – 1.02 0.214 1472 14587 all phecode
346.2
Nonspecific abnormal results of function study
Nonspecific abnormal results of function study of brain and central nervous system
 Neurological 0.907 0.747 – 1.1 0.319 120 1181 all phecode
346.3
Nonspecific abnormal findings in cerebrospinal
Nonspecific abnormal findings in cerebrospinal fluid
 Neurological 0.8 0.66 – 0.971 0.0237 110 1100 all phecode
347 Cataplexy and narcolepsy Neurological 0.896 0.732 – 1.1 0.288 101 1010 all phecode
348 Other conditions of brain Neurological 1 0.953 – 1.05 0.964 1793 17894 all phecode
348.2 Cerebral edema and compression of brain Neurological 0.979 0.914 – 1.05 0.542 905 9034 all phecode
348.4 Cerebral cysts Neurological 1.02 0.892 – 1.17 0.75 229 2290 all phecode
348.7 Coma Neurological 1.09 0.948 – 1.25 0.233 229 2275 all phecode
348.8 Encephalopathy, not elsewhere classified Neurological 1.04 0.968 – 1.11 0.295 853 8479 all phecode
348.9 Other conditions of brain, NOS Neurological 0.998 0.956 – 1.04 0.914 2341 23287 all phecode
349
Other and unspecified disorders of the nervous
Other and unspecified disorders of the nervous system
 Neurological 0.993 0.928 – 1.06 0.84 941 9385 all phecode
350 Abnormal movement Neurological 0.989 0.964 – 1.02 0.424 6706 38762 all phecode
350.1 Abnormal involuntary movements Neurological 0.994 0.959 – 1.03 0.76 3273 30524 all phecode
350.2 Abnormality of gait Neurological 0.966 0.934 – 0.999 0.0463 3920 30520 all phecode
350.3 Lack of coordination Neurological 0.993 0.931 – 1.06 0.825 1062 10554 all phecode
350.5 Abnormal reflex Neurological 0.937 0.811 – 1.08 0.382 200 1988 all phecode
350.6 Disturbances of sensation of smell and taste Neurological 1.05 0.963 – 1.14 0.271 558 5576 all phecode
351 Other peripheral nerve disorders Neurological 0.992 0.967 – 1.02 0.54 7401 34460 all phecode
352 Disorders of other cranial nerves Neurological 0.971 0.924 – 1.02 0.253 1714 17106 all phecode
352.1 Trigeminal nerve disorders [CN5] Neurological 0.892 0.815 – 0.976 0.0128 535 5344 all phecode
352.2 Facial nerve disorders [CN7] Neurological 0.986 0.916 – 1.06 0.713 783 7826 all phecode
353 Nerve root and plexus disorders Neurological 1.01 0.975 – 1.04 0.657 4256 33369 all phecode
353.1 Nerve plexus lesions Neurological 0.987 0.889 – 1.1 0.802 390 3900 all phecode
353.2 Nerve root lesions Neurological 0.942 0.79 – 1.12 0.509 130 1287 all phecode
355 Complex regional/central pain syndrome Neurological 0.912 0.833 – 0.998 0.0458 531 5295 all phecode
355.1 Chronic pain syndrome Neurological 0.996 0.927 – 1.07 0.924 843 8386 all phecode
356 Hereditary and idiopathic peripheral neuropathy Neurological 0.978 0.937 – 1.02 0.317 2335 20731 all phecode
357 Inflammatory and toxic neuropathy Neurological 0.993 0.958 – 1.03 0.691 3472 29956 all phecode
358 Myoneural disorders Neurological 1.02 0.956 – 1.08 0.601 1147 11391 all phecode
358.1 Myasthenia gravis Neurological 1.03 0.833 – 1.27 0.793 109 1082 all phecode
359 Muscular dystrophies and other myopathies Neurological 0.96 0.903 – 1.02 0.184 1134 11274 all phecode
359.1 Muscular dystrophies Neurological 0.863 0.67 – 1.11 0.256 64 632 all phecode
359.2 Myopathy Neurological 0.957 0.899 – 1.02 0.165 1092 10843 all phecode
360 Disorders of the globe Sense Organs 0.99 0.83 – 1.18 0.912 131 1276 all phecode
360.2 Progressive myopia Sense Organs 1.03 0.799 – 1.32 0.83 65 640 all phecode
361 Retinal detachments and defects Sense Organs 0.934 0.865 – 1.01 0.077 733 7131 all phecode
361.1 Retinal detachment with retinal defect Sense Organs 0.958 0.853 – 1.08 0.467 302 2962 all phecode
362 Other retinal disorders Sense Organs 1.03 0.989 – 1.06 0.171 3569 22997 all phecode
362.2
Degeneration of macula and posterior pole of
Degeneration of macula and posterior pole of retina
 Sense Organs 1.05 1.01 – 1.1 0.0221 2172 15483 all phecode
362.21 Macular degeneration, dry Sense Organs 1.01 0.918 – 1.12 0.772 419 3438 all phecode
362.22 Macular degeneration, wet Sense Organs 0.952 0.802 – 1.13 0.572 148 1184 all phecode
362.23 Cystoid macular degeneration of retina Sense Organs 1.06 0.955 – 1.17 0.278 408 3839 all phecode
362.26 Macular puckering of retina Sense Organs 1.06 0.99 – 1.13 0.0951 976 8610 all phecode
362.27 Drusen (degenerative) of retina Sense Organs 1.06 0.964 – 1.16 0.237 488 4558 all phecode
362.29 Macular degeneration (senile) of retina NOS Sense Organs 1.04 0.994 – 1.1 0.086 1883 13955 all phecode
362.3 Other nondiabetic retinopathy Sense Organs 0.971 0.909 – 1.04 0.387 976 8527 all phecode
362.31 Separation of retinal layers Sense Organs 0.993 0.899 – 1.1 0.89 413 4056 all phecode
362.4 Retinal vascular changes and abnomalities Sense Organs 0.98 0.905 – 1.06 0.626 662 5933 all phecode
362.6 Peripheral retinal degenerations Sense Organs 1.03 0.93 – 1.14 0.567 392 3787 all phecode
362.7 Hereditary retinal dystrophies Sense Organs 1 0.871 – 1.16 0.951 215 2103 all phecode
362.8 Retinal hemorrhage/ischemia Sense Organs 0.885 0.776 – 1.01 0.0673 241 2368 all phecode
362.9 Retinal edema Sense Organs 0.905 0.806 – 1.02 0.094 324 2936 all phecode
363
Chorioretinal inflammations, scars, and other
Chorioretinal inflammations, scars, and other disorders of choroid
 Sense Organs 1.02 0.926 – 1.12 0.733 492 4746 all phecode
363.3 Chorioretinal scars Sense Organs 1.02 0.911 – 1.14 0.738 332 3184 all phecode
364 Corneal opacity and other disorders of cornea Sense Organs 1.02 0.962 – 1.09 0.456 1132 10772 all phecode
364.1 Corneal opacity Sense Organs 0.906 0.815 – 1.01 0.0651 394 3846 all phecode
364.2 Corneal edema Sense Organs 0.92 0.759 – 1.12 0.396 123 1208 all phecode
364.4 Corneal degenerations Sense Organs 0.946 0.853 – 1.05 0.296 402 3962 all phecode
364.41 Keratoconus Sense Organs 1.03 0.808 – 1.31 0.822 75 739 all phecode
364.5 Corneal dystrophy Sense Organs 1.14 1.04 – 1.25 0.00718 502 4682 all phecode
364.51 Fuchs' dystrophy Sense Organs 1.08 0.946 – 1.22 0.265 266 2521 all phecode
364.9 Cornea replaced by transplant Sense Organs 1.1 0.886 – 1.37 0.385 91 885 all phecode
365 Glaucoma Sense Organs 0.993 0.953 – 1.03 0.719 2672 21326 all phecode
365.1 Open-angle glaucoma Sense Organs 0.984 0.911 – 1.06 0.693 705 6491 all phecode
365.11 Primary open angle glaucoma Sense Organs 1.02 0.917 – 1.13 0.763 403 3681 all phecode
365.2 Primary angle-closure glaucoma Sense Organs 1.02 0.896 – 1.17 0.747 251 2370 all phecode
366 Cataract Sense Organs 1.02 0.991 – 1.04 0.205 8611 28043 all phecode
366.1 Nonsenile Cataract Sense Organs 1.02 0.88 – 1.17 0.834 207 1979 all phecode
366.2 Senile cataract Sense Organs 1.03 1 – 1.07 0.0384 5480 24980 all phecode
367
Disorders of refraction and accommodation
Disorders of refraction and accommodation; blindness and low vision
 Sense Organs 1.01 0.985 – 1.03 0.469 8967 37779 all phecode
367.1 Myopia Sense Organs 1.01 0.977 – 1.04 0.633 5014 34677 all phecode
367.2 Astigmatism Sense Organs 1.03 0.994 – 1.06 0.111 4161 32463 all phecode
367.8 Hypermetropia Sense Organs 1.04 0.996 – 1.09 0.0728 2039 18599 all phecode
367.9 Blindness and low vision Sense Organs 0.953 0.899 – 1.01 0.109 1277 12356 all phecode
368 Visual disturbances Sense Organs 1.03 0.997 – 1.05 0.0839 5715 39599 all phecode
368.1 Amblyopia Sense Organs 1.07 0.987 – 1.16 0.101 651 6479 all phecode
368.2 Diplopia and disorders of binocular vision Sense Organs 0.967 0.908 – 1.03 0.296 1087 10786 all phecode
368.3 Anisometropia Sense Organs 0.921 0.804 – 1.06 0.235 219 2168 all phecode
368.4 Visual field defects Sense Organs 0.982 0.924 – 1.04 0.568 1132 11173 all phecode
368.9 Subjective visual disturbances Sense Organs 1 0.94 – 1.07 0.958 1070 10620 all phecode
368.91 Psychophysical visual disturbances Sense Organs 0.848 0.703 – 1.02 0.0841 120 1171 all phecode
369 Infection of the eye Sense Organs 0.992 0.956 – 1.03 0.671 3185 28240 all phecode
369.2 Eye infection, viral Sense Organs 0.998 0.909 – 1.1 0.968 502 4954 all phecode
369.5 Conjunctivitis, infectious Sense Organs 0.99 0.951 – 1.03 0.623 2716 24970 all phecode
370 Keratitis Sense Organs 0.974 0.921 – 1.03 0.357 1365 13169 all phecode
370.1 Corneal ulcer Sense Organs 1.07 0.936 – 1.23 0.308 223 2194 all phecode
370.2 Superficial keratitis Sense Organs 0.949 0.868 – 1.04 0.248 546 5393 all phecode
370.3 Keratoconjunctivitis Sense Organs 0.945 0.871 – 1.03 0.181 649 6263 all phecode
370.31 Keratoconjunctivitis sicca Sense Organs 0.969 0.833 – 1.13 0.687 179 1677 all phecode
371 Inflammation of the eye Sense Organs 1.02 0.984 – 1.05 0.34 4414 32310 all phecode
371.1 Uveitis, noninfectious or NOS Sense Organs 0.999 0.914 – 1.09 0.976 541 5278 all phecode
371.2 Conjunctivitis, noninfectious Sense Organs 1.01 0.944 – 1.08 0.739 906 8939 all phecode
371.21 Allergic conjunctivitis Sense Organs 1.01 0.937 – 1.09 0.791 756 7515 all phecode
371.3 Inflammation of eyelids Sense Organs 1.01 0.979 – 1.05 0.426 3398 26983 all phecode
371.33 Noninfectious dermatoses of eyelid Sense Organs 1.01 0.851 – 1.21 0.877 133 1291 all phecode
372 Disorders of conjunctiva Sense Organs 1.08 1.02 – 1.15 0.0123 1118 10728 all phecode
374 Other disorders of eyelids Sense Organs 1 0.964 – 1.04 0.929 2940 24188 all phecode
374.1 Ectropion or entropion Sense Organs 0.95 0.86 – 1.05 0.314 431 4084 all phecode
374.2 Lagophthalmos Sense Organs 0.949 0.825 – 1.09 0.456 235 2335 all phecode
374.3 Ptosis of eyelid Sense Organs 0.967 0.908 – 1.03 0.286 1102 10734 all phecode
374.6 Dermatochalasis Sense Organs 1 0.942 – 1.07 0.889 1040 9720 all phecode
375 Disorders of lacrimal system Sense Organs 0.974 0.94 – 1.01 0.136 3694 26045 all phecode
375.1 Dry eyes Sense Organs 0.995 0.962 – 1.03 0.77 4040 26751 all phecode
375.2 Epiphora Sense Organs 0.891 0.806 – 0.985 0.0242 442 4354 all phecode
376 Disorders of the orbit Sense Organs 0.995 0.891 – 1.11 0.928 352 3508 all phecode
377 Disorders of optic nerve and visual pathways Sense Organs 1.03 0.96 – 1.1 0.423 913 9021 all phecode
377.1 Optic atrophy Sense Organs 0.982 0.871 – 1.11 0.769 283 2793 all phecode
377.3 Optic neuritis/neuropathy Sense Organs 1.04 0.953 – 1.13 0.389 585 5775 all phecode
378
Strabismus and other disorders of binocular eye
Strabismus and other disorders of binocular eye movements
 Sense Organs 0.997 0.94 – 1.06 0.91 1275 12460 all phecode
378.1 Strabismus (not specified as paralytic) Sense Organs 0.985 0.916 – 1.06 0.676 828 8130 all phecode
378.2 Nystagmus and other irregular eye movements Sense Organs 0.982 0.84 – 1.15 0.825 170 1686 all phecode
378.5 Paralytic strabismus Sense Organs 0.979 0.875 – 1.09 0.706 349 3437 all phecode
379 Other disorders of eye Sense Organs 1.03 0.999 – 1.06 0.0567 5046 29999 all phecode
379.1 Scleritis and episcleritis Sense Organs 0.882 0.753 – 1.03 0.119 176 1743 all phecode
379.2 Disorders of vitreous body Sense Organs 1.05 1.01 – 1.09 0.0119 3634 23186 all phecode
379.3 Aphakia and other disorders of lens Sense Organs 0.851 0.71 – 1.02 0.0786 135 1258 all phecode
379.4 Anomalies of pupillary function Sense Organs 1.04 0.917 – 1.17 0.573 287 2833 all phecode
379.5 Disorders of iris and ciliary body Sense Organs 0.981 0.868 – 1.11 0.754 304 2948 all phecode
379.51 Pigmentary iris degeneration Sense Organs 1.04 0.817 – 1.32 0.758 77 731 all phecode
379.9 Pain, swelling or discharge of eye Sense Organs 0.963 0.906 – 1.02 0.231 1129 11130 all phecode
380 Disorders of external ear Sense Organs 1.04 0.99 – 1.08 0.125 2242 20393 all phecode
380.1 Otitis externa Sense Organs 1.02 0.965 – 1.08 0.508 1469 14580 all phecode
380.4 Impacted cerumen Sense Organs 1.05 1.01 – 1.09 0.0172 2648 23557 all phecode
381 Otitis media and Eustachian tube disorders Sense Organs 0.979 0.948 – 1.01 0.196 4255 36417 all phecode
381.1 Otitis media Sense Organs 0.978 0.942 – 1.02 0.238 3079 29813 all phecode
381.11 Suppurative and unspecified otitis media Sense Organs 0.974 0.935 – 1.01 0.206 2610 25602 all phecode
381.2 Eustachian tube disorders Sense Organs 0.975 0.929 – 1.02 0.309 1816 17827 all phecode
381.3 Mastoiditis & related conditions Sense Organs 1.03 0.874 – 1.22 0.703 153 1530 all phecode
381.9 Otorrhea Sense Organs 0.965 0.866 – 1.08 0.524 372 3713 all phecode
382 Otalgia Sense Organs 0.991 0.945 – 1.04 0.697 1884 18673 all phecode
383 Otosclerosis Sense Organs 1.02 0.848 – 1.22 0.842 124 1240 all phecode
384 Other disorders of tympanic membrane Sense Organs 0.969 0.885 – 1.06 0.498 516 5156 all phecode
384.1 Myringitis Sense Organs 0.814 0.615 – 1.08 0.151 51 502 all phecode
384.4 Perforation of tympanic membrane Sense Organs 0.966 0.871 – 1.07 0.505 403 4029 all phecode
385 Other disorders of middle ear and mastoid Sense Organs 0.972 0.88 – 1.07 0.572 432 4320 all phecode
385.3 Cholesteatoma Sense Organs 0.957 0.846 – 1.08 0.49 277 2770 all phecode
385.5
Tympanosclerosis and middle ear disease related
Tympanosclerosis and middle ear disease related to otitis media
 Sense Organs 0.883 0.732 – 1.06 0.192 118 1180 all phecode
386
Vertiginous syndromes and other disorders of
Vertiginous syndromes and other disorders of vestibular system
 Sense Organs 1.04 0.99 – 1.09 0.118 1882 18186 all phecode
386.1 Meniere's disease Sense Organs 1.04 0.928 – 1.17 0.485 319 3156 all phecode
386.2 Peripheral or central vertigo Sense Organs 1.04 0.992 – 1.1 0.101 1586 15423 all phecode
386.21 Central origin vertigo Sense Organs 1.05 0.992 – 1.12 0.0901 1208 11844 all phecode
386.3 Labyrinthitis Sense Organs 1.05 0.991 – 1.1 0.102 1482 14530 all phecode
386.9
Dizziness and giddiness (Light-headedness and
Dizziness and giddiness (Light-headedness and vertigo)
 Sense Organs 1.02 0.996 – 1.05 0.0929 6933 38286 all phecode
388 Other disorders of ear Sense Organs 1.06 0.988 – 1.13 0.107 960 9501 all phecode
389 Hearing loss Sense Organs 1.01 0.987 – 1.04 0.378 8182 38069 all phecode
389.1 Sensorineural hearing loss Sense Organs 1.01 0.98 – 1.05 0.436 4107 29258 all phecode
389.2 Conductive hearing loss Sense Organs 0.93 0.869 – 0.996 0.0384 905 9042 all phecode
389.3 Degenerative and vascular disorders of ear Sense Organs 0.993 0.852 – 1.16 0.927 192 1808 all phecode
389.4 Tinnitus Sense Organs 1.04 0.992 – 1.08 0.114 2291 22130 all phecode
389.5 Disorders of acoustic nerve Sense Organs 1.02 0.851 – 1.23 0.804 124 1229 all phecode
394 Rheumatic disease of the heart valves Circulatory System 1.03 0.975 – 1.09 0.303 1458 13732 all phecode
394.1 Mitral valve stenosis and aortic valve stenosis Circulatory System 1.07 0.953 – 1.19 0.265 350 3415 all phecode
394.2 Mitral valve disease Circulatory System 1.03 0.932 – 1.13 0.596 462 4560 all phecode
394.3 Aortic valve disease Circulatory System 1.04 0.891 – 1.22 0.615 176 1691 all phecode
394.4 Acute rheumatic heart disease Circulatory System 0.828 0.63 – 1.09 0.177 55 546 all phecode
394.7 Disease of tricuspid valve Circulatory System 1.02 0.933 – 1.11 0.698 587 5739 all phecode
395 Heart valve disorders Circulatory System 1.05 1.01 – 1.08 0.00658 3976 28748 all phecode
395.1 Nonrheumatic mitral valve disorders Circulatory System 1.04 0.994 – 1.09 0.0934 2175 20441 all phecode
395.2 Nonrheumatic aortic valve disorders Circulatory System 1.07 1.02 – 1.12 0.00488 2060 17194 all phecode
395.3 Nonrheumatic tricuspid valve disorders Circulatory System 1.04 0.949 – 1.14 0.392 493 4864 all phecode
395.4 Nonrheumatic pulmonary valve disorders Circulatory System 0.942 0.77 – 1.15 0.558 108 1080 all phecode
395.6 Heart valve replaced Circulatory System 1.04 0.982 – 1.11 0.173 1177 10833 all phecode
396 Abnormal heart sounds Circulatory System 1.03 0.997 – 1.06 0.0782 4718 34395 all phecode
401 Hypertension Circulatory System 0.991 0.971 – 1.01 0.404 23317 23367 all phecode
401.1 Essential hypertension Circulatory System 0.99 0.97 – 1.01 0.366 23158 23364 all phecode
401.2 Hypertensive heart and/or renal disease Circulatory System 1 0.965 – 1.04 0.857 3503 14616 all phecode
401.21 Hypertensive heart disease Circulatory System 1.08 1.01 – 1.16 0.0271 893 6607 all phecode
401.22 Hypertensive chronic kidney disease Circulatory System 0.982 0.939 – 1.03 0.428 2584 13072 all phecode
401.3 Other hypertensive complications Circulatory System 1.03 0.992 – 1.08 0.113 2679 15833 all phecode
411 Ischemic Heart Disease Circulatory System 1.07 1.05 – 1.1 4.54e-08 8807 30299 all phecode
411.1 Unstable angina (intermediate coronary syndrome) Circulatory System 1.15 1.07 – 1.23 8.32e-05 937 8574 all phecode
411.2 Myocardial infarction Circulatory System 1.09 1.05 – 1.13 6.57e-06 3594 21716 all phecode
411.3 Angina pectoris Circulatory System 1.08 1.04 – 1.13 0.000247 2485 18304 all phecode
411.4 Coronary atherosclerosis Circulatory System 1.09 1.06 – 1.12 1.35e-09 7555 27492 all phecode
411.41 Aneurysm and dissection of heart Circulatory System 1.13 0.951 – 1.33 0.17 156 1529 all phecode
411.8
Other chronic ischemic heart disease
Other chronic ischemic heart disease, unspecified
 Circulatory System 1.1 1.07 – 1.13 5.09e-10 6331 25741 all phecode
411.9
Other acute and subacute forms of ischemic
Other acute and subacute forms of ischemic heart disease
 Circulatory System 1.07 0.967 – 1.18 0.195 442 4211 all phecode
414 Other forms of chronic heart disease Circulatory System 1.12 1.07 – 1.16 1.92e-08 3101 22616 all phecode
414.2 ASCVD Circulatory System 1.14 1.05 – 1.23 0.00117 718 6816 all phecode
415 Pulmonary heart disease Circulatory System 1.02 0.982 – 1.05 0.346 3366 30208 all phecode
415.1 Acute pulmonary heart disease Circulatory System 1.03 0.981 – 1.08 0.239 1912 19014 all phecode
415.11 Pulmonary embolism and infarction, acute Circulatory System 1.03 0.98 – 1.08 0.267 1906 18953 all phecode
415.2 Chronic pulmonary heart disease Circulatory System 1.02 0.975 – 1.08 0.343 1808 17605 all phecode
415.21 Primary pulmonary hypertension Circulatory System 1.01 0.93 – 1.09 0.892 706 7032 all phecode
416 Cardiomegaly Circulatory System 0.945 0.892 – 1 0.0578 1254 12372 all phecode
418 Nonspecific chest pain Circulatory System 1.03 1.01 – 1.05 0.0144 12650 33952 all phecode
418.1 Precordial pain Circulatory System 1.07 1.01 – 1.13 0.0175 1471 13782 all phecode
420 Carditis Circulatory System 1.02 0.971 – 1.08 0.401 1588 15680 all phecode
420.1 Myocarditis Circulatory System 0.932 0.758 – 1.15 0.502 97 958 all phecode
420.2 Pericarditis Circulatory System 1.01 0.942 – 1.09 0.746 842 8402 all phecode
420.21 Acute pericarditis Circulatory System 0.987 0.848 – 1.15 0.871 177 1764 all phecode
420.22 Chronic pericarditis Circulatory System 1.03 0.848 – 1.24 0.787 117 1153 all phecode
420.3 Endocarditis Circulatory System 1.01 0.937 – 1.09 0.806 764 7535 all phecode
425 Cardiomyopathy Circulatory System 1.04 0.998 – 1.09 0.062 2078 19881 all phecode
425.1 Primary/intrinsic cardiomyopathies Circulatory System 1.03 0.987 – 1.08 0.164 1989 19025 all phecode
425.11 Hypertrophic obstructive cardiomyopathy Circulatory System 0.984 0.855 – 1.13 0.826 208 2050 all phecode
425.12 Other hypertrophic cardiomyopathy Circulatory System 1.02 0.882 – 1.18 0.793 201 1992 all phecode
425.2 Secondary/extrinsic cardiomyopathies Circulatory System 1 0.894 – 1.12 0.976 317 3170 all phecode
425.8 Other cardiomyopathy Circulatory System 1.04 0.839 – 1.28 0.738 95 931 all phecode
426 Cardiac conduction disorders Circulatory System 1.02 0.998 – 1.04 0.0786 12327 25440 all phecode
426.2 Atrioventricular [AV] block Circulatory System 1.04 0.991 – 1.1 0.105 1903 11501 all phecode
426.21 First degree AV block Circulatory System 1.03 0.969 – 1.09 0.354 1313 8899 all phecode
426.22 Mobitz II AV block Circulatory System 1.19 0.931 – 1.51 0.168 64 553 all phecode
426.23 Second degree AV block Circulatory System 1.04 0.908 – 1.2 0.558 216 1925 all phecode
426.24 Atrioventricular block, complete Circulatory System 1.1 1 – 1.21 0.0477 461 3823 all phecode
426.25 Other heart block Circulatory System 1.12 0.966 – 1.3 0.132 203 1803 all phecode
426.3 Bundle branch block Circulatory System 1.06 1.01 – 1.11 0.0102 2306 13999 all phecode
426.31 Right bundle branch block Circulatory System 1.05 0.993 – 1.11 0.0855 1423 10758 all phecode
426.32 Left bundle branch block Circulatory System 1.06 0.994 – 1.14 0.0759 969 8110 all phecode
426.4 Anomalous atrioventricular excitation Circulatory System 0.971 0.771 – 1.22 0.805 82 820 all phecode
426.7 Abnormal electrocardiogram [ECG] [EKG] Circulatory System 1.02 0.994 – 1.04 0.152 10577 25186 all phecode
426.8 Other cardiac conduction disorders Circulatory System 1.02 0.939 – 1.1 0.676 679 6650 all phecode
426.9 Cardiac pacemaker/device in situ Circulatory System 1.04 0.985 – 1.09 0.165 1754 11536 all phecode
426.91 Cardiac pacemaker in situ Circulatory System 1.02 0.959 – 1.08 0.534 1171 8184 all phecode
426.92 Cardiac defibrillator in situ Circulatory System 1.08 1.01 – 1.16 0.0326 846 7320 all phecode
427 Cardiac dysrhythmias Circulatory System 1.01 0.987 – 1.03 0.498 17397 25735 all phecode
427.1 Paroxysmal tachycardia, unspecified Circulatory System 1.03 0.984 – 1.07 0.214 2474 18178 all phecode
427.11 Paroxysmal supraventricular tachycardia Circulatory System 1.01 0.962 – 1.07 0.615 1595 14293 all phecode
427.12 Paroxysmal ventricular tachycardia Circulatory System 1.06 0.998 – 1.13 0.0589 1181 9915 all phecode
427.2 Atrial fibrillation and flutter Circulatory System 1.01 0.974 – 1.04 0.688 5313 18688 all phecode
427.21 Atrial fibrillation Circulatory System 1.01 0.973 – 1.04 0.737 5188 18409 all phecode
427.22 Atrial flutter Circulatory System 1.02 0.969 – 1.08 0.437 1693 11042 all phecode
427.3 Other specified cardiac dysrhythmias Circulatory System 1.02 0.99 – 1.04 0.234 8688 25552 all phecode
427.4 Cardiac arrest and ventricular fibrillation Circulatory System 0.994 0.91 – 1.09 0.897 536 5233 all phecode
427.41 Ventricular fibrillation and flutter Circulatory System 1.09 0.946 – 1.25 0.237 216 2118 all phecode
427.42 Cardiac arrest Circulatory System 0.995 0.898 – 1.1 0.921 410 4034 all phecode
427.5 Arrhythmia (cardiac) NOS Circulatory System 1 0.975 – 1.03 0.864 6905 25457 all phecode
427.6 Premature beats Circulatory System 1.07 1.02 – 1.11 0.00479 2359 16248 all phecode
427.61 Supraventricular premature beats Circulatory System 1.03 0.954 – 1.12 0.417 670 6287 all phecode
427.7 Tachycardia NOS Circulatory System 1.02 0.987 – 1.05 0.273 5124 25531 all phecode
427.8 Sinoatrial node dysfunction (Bradycardia) Circulatory System 1.01 0.943 – 1.08 0.765 912 7501 all phecode
427.9 Palpitations Circulatory System 1.01 0.982 – 1.05 0.395 4430 24505 all phecode
428 Congestive heart failure; nonhypertensive Circulatory System 1.03 0.999 – 1.07 0.0574 4300 23663 all phecode
428.1 Congestive heart failure (CHF) NOS Circulatory System 1.03 0.998 – 1.07 0.0626 3756 22446 all phecode
428.2 Heart failure NOS Circulatory System 1.02 0.986 – 1.06 0.226 3701 21722 all phecode
428.3
Heart failure with reduced EF [Systolic or
Heart failure with reduced EF [Systolic or combined heart failure]
 Circulatory System 1.04 0.991 – 1.09 0.106 1765 14476 all phecode
428.4
Heart failure with preserved EF [Diastolic
Heart failure with preserved EF [Diastolic heart failure]
 Circulatory System 1 0.953 – 1.06 0.903 1648 13395 all phecode
429
Ill-defined descriptions and complications of
Ill-defined descriptions and complications of heart disease
 Circulatory System 1.03 1.01 – 1.05 0.0151 12635 32504 all phecode
429.1 Heart transplant/surgery Circulatory System 1.04 0.98 – 1.1 0.2 1219 11696 all phecode
429.2 Abnormal function study of cardiovascular system Circulatory System 1.04 1.01 – 1.07 0.0106 6322 29232 all phecode
429.3 Symptoms involving cardiovascular system Circulatory System 1.02 1 – 1.05 0.0427 9650 32421 all phecode
429.9 Cardiac complications, not elsewhere classified Circulatory System 1.05 0.973 – 1.13 0.21 723 7072 all phecode
430 Intracranial hemorrhage Circulatory System 0.984 0.915 – 1.06 0.671 789 7842 all phecode
430.1 Subarachnoid hemorrhage Circulatory System 0.974 0.858 – 1.11 0.686 261 2610 all phecode
430.2 Intracerebral hemorrhage Circulatory System 0.95 0.854 – 1.06 0.343 368 3671 all phecode
430.3 Subdural hemorrhage Circulatory System 0.987 0.874 – 1.12 0.84 272 2680 all phecode
433 Cerebrovascular disease Circulatory System 1.04 1.01 – 1.07 0.0215 5463 32242 all phecode
433.1 Occlusion and stenosis of precerebral arteries Circulatory System 1.09 1.04 – 1.14 0.000409 1978 16212 all phecode
433.11
Occlusion of cerebral arteries, with cerebral
Occlusion of cerebral arteries, with cerebral infarction
 Circulatory System 1.15 1.02 – 1.31 0.0251 260 2517 all phecode
433.12 Cerebral atherosclerosis Circulatory System 1.22 0.973 – 1.54 0.0849 80 789 all phecode
433.2 Occlusion of cerebral arteries Circulatory System 1.01 0.971 – 1.06 0.549 2437 21732 all phecode
433.21
Cerebral artery occlusion, with cerebral
Cerebral artery occlusion, with cerebral infarction
 Circulatory System 1.01 0.969 – 1.06 0.603 2357 21103 all phecode
433.3 Cerebral ischemia Circulatory System 1.03 0.995 – 1.08 0.0889 2780 22868 all phecode
433.31 Transient cerebral ischemia Circulatory System 1.03 0.989 – 1.08 0.145 2409 20762 all phecode
433.5 Cerebral aneurysm Circulatory System 0.973 0.886 – 1.07 0.567 474 4724 all phecode
433.6 Acute, but ill-defined cerebrovascular disease Circulatory System 1.05 0.958 – 1.16 0.286 464 4518 all phecode
433.8 Late effects of cerebrovascular disease Circulatory System 0.994 0.92 – 1.08 0.89 695 6822 all phecode
440 Atherosclerosis Circulatory System 1.07 1.02 – 1.11 0.00272 2477 19724 all phecode
440.1 Atherosclerosis of renal artery Circulatory System 1.05 0.923 – 1.21 0.436 231 2291 all phecode
440.2 Atherosclerosis of the extremities Circulatory System 1.05 0.997 – 1.11 0.0641 1516 13532 all phecode
440.21
Atherosclerosis of native arteries of the
Atherosclerosis of native arteries of the extremities with ulceration or gangrene
 Circulatory System 1.03 0.91 – 1.17 0.627 274 2669 all phecode
440.22
Atherosclerosis of native arteries of the
Atherosclerosis of native arteries of the extremities with intermittent claudication
 Circulatory System 1.07 1 – 1.14 0.0398 1040 9647 all phecode
440.9 Atherosclerosis of aorta Circulatory System 1.13 1.05 – 1.21 0.00106 846 8124 all phecode
441 Vascular insufficiency of intestine Circulatory System 0.99 0.903 – 1.08 0.826 515 5115 all phecode
441.1 Acute vascular insufficiency of intestine Circulatory System 0.995 0.87 – 1.14 0.942 240 2387 all phecode
441.2 Chronic vascular insufficiency of intestine Circulatory System 1.03 0.874 – 1.22 0.714 154 1536 all phecode
442 Other aneurysm Circulatory System 1.02 0.983 – 1.06 0.259 2779 21466 all phecode
442.1 Aortic aneurysm Circulatory System 1.04 0.993 – 1.09 0.0979 2054 16492 all phecode
442.11 Abdominal aortic aneurysm Circulatory System 1.07 1.01 – 1.14 0.0215 1189 10558 all phecode
442.2 Aneurysm of iliac artery Circulatory System 1.05 0.913 – 1.22 0.473 202 2002 all phecode
442.3 Aneurysm of artery of lower extremity Circulatory System 0.987 0.848 – 1.15 0.869 179 1765 all phecode
442.4 Arterial dissection Circulatory System 0.884 0.762 – 1.03 0.105 184 1840 all phecode
442.8 Aneurysm of other specified artery Circulatory System 1.01 0.907 – 1.11 0.92 399 3978 all phecode
443 Peripheral vascular disease Circulatory System 1.04 1 – 1.08 0.034 3086 24814 all phecode
443.1 Raynaud's syndrome Circulatory System 1.01 0.94 – 1.1 0.71 742 7390 all phecode
443.7
Peripheral angiopathy in diseases classified
Peripheral angiopathy in diseases classified elsewhere
 Circulatory System 1.07 0.927 – 1.22 0.371 220 2087 all phecode
443.8 Other specified peripheral vascular diseases Circulatory System 1.04 0.996 – 1.08 0.0759 2557 21985 all phecode
443.9 Peripheral vascular disease, unspecified Circulatory System 1.05 1 – 1.1 0.0323 2341 18862 all phecode
444 Arterial embolism and thrombosis Circulatory System 1.03 0.955 – 1.1 0.481 848 8423 all phecode
444.1
Arterial embolism and thrombosis of lower
Arterial embolism and thrombosis of lower extremity artery
 Circulatory System 0.991 0.881 – 1.12 0.886 313 3099 all phecode
444.2 Embolism and thrombosis of abdominal aorta Circulatory System 1.14 0.965 – 1.35 0.124 155 1548 all phecode
446 Polyarteritis nodosa and allied conditions Circulatory System 1.03 0.932 – 1.13 0.602 460 4559 all phecode
446.4 Wegener's granulomatosis Circulatory System 1.02 0.845 – 1.24 0.811 109 1075 all phecode
446.5 Giant cell arteritis Circulatory System 1.06 0.848 – 1.34 0.593 79 749 all phecode
446.9 Arteritis NOS Circulatory System 0.968 0.858 – 1.09 0.593 289 2876 all phecode
447 Other disorders of arteries and arterioles Circulatory System 1.03 0.993 – 1.08 0.107 2647 22765 all phecode
447.1 Stricture of artery Circulatory System 1.07 0.982 – 1.18 0.116 523 5163 all phecode
447.7 Aortic ectasia Circulatory System 0.988 0.918 – 1.06 0.736 804 7938 all phecode
448 Disease of capillaries Circulatory System 0.999 0.942 – 1.06 0.981 1237 12127 all phecode
450 Noninfectious disorders of lymphatic channels Circulatory System 0.972 0.929 – 1.02 0.209 2104 20985 all phecode
451 Phlebitis and thrombophlebitis Circulatory System 0.967 0.896 – 1.04 0.385 738 7355 all phecode
451.2
Phlebitis and thrombophlebitis of lower
Phlebitis and thrombophlebitis of lower extremities
 Circulatory System 0.95 0.833 – 1.08 0.437 244 2437 all phecode
452 Other venous embolism and thrombosis Circulatory System 0.997 0.967 – 1.03 0.85 4957 29867 all phecode
452.1 Iatrogenic pulmonary embolism and infarction Circulatory System 1.01 0.888 – 1.14 0.914 276 2747 all phecode
452.2 Deep vein thrombosis [DVT] Circulatory System 0.987 0.952 – 1.02 0.496 3260 26940 all phecode
452.8 Postphlebitic syndrome Circulatory System 1.14 0.962 – 1.35 0.129 154 1529 all phecode
453 Chronic venous hypertension Circulatory System 0.993 0.865 – 1.14 0.92 220 2168 all phecode
454 Varicose veins Circulatory System 0.965 0.928 – 1 0.0753 2827 24555 all phecode
454.1 Varicose veins of lower extremity Circulatory System 0.969 0.929 – 1.01 0.148 2469 21426 all phecode
454.11 Varicose veins of lower extremity, symptomtic Circulatory System 0.961 0.912 – 1.01 0.137 1565 15056 all phecode
455 Hemorrhoids Circulatory System 1.05 1.02 – 1.08 0.00112 5799 29818 all phecode
456 Chronic venous insufficiency [CVI] Circulatory System 0.972 0.936 – 1.01 0.147 3097 24898 all phecode
457
Encounter for long-term (current) use of
Encounter for long-term (current) use of anticoagulants, antithrombotics, aspirin
 Circulatory System 1.09 1.04 – 1.14 0.000473 2095 15309 all phecode
457.2
Encounter for long-term (current) use of
Encounter for long-term (current) use of antiplatelets/antithrombotics
 Circulatory System 1.13 1 – 1.26 0.0447 324 3221 all phecode
457.3 Encounter for long-term (current) use of aspirin Circulatory System 1.09 1.04 – 1.14 0.000713 1973 14689 all phecode
458 Hypotension Circulatory System 1.01 0.981 – 1.04 0.489 5091 32185 all phecode
458.1 Orthostatic hypotension Circulatory System 0.971 0.917 – 1.03 0.3 1344 12938 all phecode
458.2 Iatrogenic hypotension Circulatory System 1.02 0.96 – 1.09 0.499 1109 11012 all phecode
458.9 Hypotension NOS Circulatory System 1.01 0.98 – 1.04 0.484 4618 31186 all phecode
459 Other disorders of circulatory system Circulatory System 1.01 0.989 – 1.04 0.273 7825 34792 all phecode
459.1 Hemorrhage NOS Circulatory System 1.02 0.945 – 1.09 0.663 834 8215 all phecode
459.7 Blood vessel replaced Circulatory System 1.01 0.952 – 1.07 0.787 1305 13023 all phecode
459.9 Circulatory disease NEC Circulatory System 1.02 0.992 – 1.05 0.173 6706 33592 all phecode
464 Acute sinusitis Respiratory 1 0.97 – 1.03 0.997 4792 32137 all phecode
465
Acute upper respiratory infections of multiple
Acute upper respiratory infections of multiple or unspecified sites
 Respiratory 1.01 0.986 – 1.03 0.433 9601 35915 all phecode
465.2 Acute pharyngitis Respiratory 1.01 0.979 – 1.04 0.581 5310 32365 all phecode
465.4 Acute laryngitis and tracheitis Respiratory 1.02 0.926 – 1.13 0.68 443 4428 all phecode
470 Septal Deviations/Turbinate Hypertrophy Respiratory 0.975 0.928 – 1.02 0.311 1797 17640 all phecode
471 Nasal polyps Respiratory 0.958 0.881 – 1.04 0.314 592 5881 all phecode
472 Chronic pharyngitis and nasopharyngitis Respiratory 0.968 0.921 – 1.02 0.191 1797 16986 all phecode
473 Diseases of the larynx and vocal cords Respiratory 0.991 0.954 – 1.03 0.641 2983 25244 all phecode
473.1 Chronic laryngitis Respiratory 0.991 0.782 – 1.26 0.941 68 674 all phecode
473.3 Paralysis/spasm of vocal cords or larynx Respiratory 1.11 1.02 – 1.2 0.0161 628 6254 all phecode
473.4 Voice disturbance Respiratory 1 0.958 – 1.04 0.981 2336 21975 all phecode
474 Acute and chronic tonsillitis Respiratory 1 0.936 – 1.08 0.914 880 7892 all phecode
474.1 Acute tonsillitis Respiratory 1.03 0.922 – 1.15 0.591 335 3181 all phecode
474.2 Chronic tonsillitis and adenoiditis Respiratory 1.01 0.934 – 1.09 0.808 700 6445 all phecode
475 Chronic sinusitis Respiratory 0.991 0.96 – 1.02 0.593 4378 27891 all phecode
475.9 Postnasal drip Respiratory 1.02 0.956 – 1.1 0.508 922 9017 all phecode
476 Allergic rhinitis Respiratory 0.991 0.97 – 1.01 0.396 12687 28117 all phecode
477 Epistaxis or throat hemorrhage Respiratory 1.08 1.01 – 1.14 0.0178 1150 11318 all phecode
478 Throat pain Respiratory 1.09 0.985 – 1.2 0.0942 426 4195 all phecode
479 Other upper respiratory disease Respiratory 1 0.973 – 1.03 0.896 5627 28048 all phecode
480 Pneumonia Respiratory 1.03 1.01 – 1.06 0.0178 5947 37034 all phecode
480.1 Bacterial pneumonia Respiratory 1.06 0.997 – 1.13 0.0618 1155 11495 all phecode
480.11 Pneumococcal pneumonia Respiratory 1.09 1 – 1.19 0.0439 568 5644 all phecode
480.12 Pseudomonal pneumonia Respiratory 1 0.852 – 1.18 0.996 153 1523 all phecode
480.13 MRSA pneumonia Respiratory 0.883 0.726 – 1.07 0.213 117 1165 all phecode
480.2 Viral pneumonia Respiratory 1.08 0.943 – 1.25 0.255 202 1992 all phecode
480.3 Pneumonia due to fungus (mycoses) Respiratory 1.04 0.891 – 1.22 0.594 159 1590 all phecode
480.5 Bronchopneumonia and lung abscess Respiratory 1.01 0.849 – 1.21 0.881 135 1312 all phecode
481 Influenza Respiratory 1.04 0.981 – 1.1 0.201 1355 13284 all phecode
483 Acute bronchitis and bronchiolitis Respiratory 1.01 0.972 – 1.04 0.691 3412 29871 all phecode
495 Asthma Respiratory 0.978 0.955 – 1 0.0728 8671 33569 all phecode
495.1 Chronic obstructive asthma Respiratory 1.02 0.922 – 1.13 0.675 397 3925 all phecode
495.11 Chronic obstructive asthma with exacerbation Respiratory 1.2 0.942 – 1.52 0.141 81 802 all phecode
495.2 Asthma with exacerbation Respiratory 0.998 0.948 – 1.05 0.935 1629 16033 all phecode
496 Chronic airway obstruction Respiratory 0.992 0.963 – 1.02 0.581 5343 28343 all phecode
496.1 Emphysema Respiratory 1.01 0.964 – 1.05 0.725 2134 19414 all phecode
496.2 Chronic bronchitis Respiratory 0.988 0.956 – 1.02 0.472 4128 26624 all phecode
496.21 Obstructive chronic bronchitis Respiratory 0.993 0.959 – 1.03 0.693 3747 25467 all phecode
496.3 Bronchiectasis Respiratory 1.01 0.928 – 1.11 0.752 549 5453 all phecode
497 Bronchitis Respiratory 1.01 0.96 – 1.05 0.8 1946 18824 all phecode
498 Acute bronchospasm Respiratory 0.945 0.862 – 1.04 0.231 496 4943 all phecode
499 Cystic fibrosis Respiratory 0.993 0.841 – 1.17 0.937 151 1510 all phecode
500 Lung disease due to external agents Respiratory 0.911 0.835 – 0.993 0.0341 557 5551 all phecode
500.1 Extrinsic allergic alveolitis Respiratory 0.861 0.696 – 1.06 0.167 92 920 all phecode
500.2 Pneumoconiosis Respiratory 0.963 0.772 – 1.2 0.742 78 764 all phecode
501 Pneumonitis due to inhalation of food or vomitus Respiratory 1.06 0.975 – 1.15 0.172 634 6225 all phecode
502 Postinflammatory pulmonary fibrosis Respiratory 0.99 0.92 – 1.07 0.787 815 8076 all phecode
503 Pulmonary congestion and hypostasis Respiratory 1.02 0.952 – 1.1 0.539 835 8243 all phecode
504 Other alveolar and parietoalveolar pneumonopathy Respiratory 0.992 0.911 – 1.08 0.857 595 5878 all phecode
504.1 Idiopathic fibrosing alveolitis Respiratory 1.07 0.955 – 1.21 0.236 311 3084 all phecode
505 Other pulmonary inflamation or edema Respiratory 1.02 0.974 – 1.08 0.345 1638 15749 all phecode
506 Empyema and pneumothorax Respiratory 1.03 0.995 – 1.08 0.0858 2894 25235 all phecode
507 Pleurisy; pleural effusion Respiratory 0.991 0.953 – 1.03 0.631 2916 26208 all phecode
508
Pulmonary collapse; interstitial and
Pulmonary collapse; interstitial and compensatory emphysema
 Respiratory 1.01 0.972 – 1.06 0.509 2382 22588 all phecode
509 Respiratory failure, insufficiency, arrest Respiratory 1.03 0.998 – 1.07 0.0626 4032 29477 all phecode
509.1 Respiratory failure Respiratory 1.02 0.973 – 1.07 0.4 1937 18949 all phecode
509.2 Respiratory insufficiency Respiratory 1.02 0.955 – 1.08 0.625 1174 11679 all phecode
509.3
Pulmonary insufficiency or respiratory failure
Pulmonary insufficiency or respiratory failure following trauma and surgery
 Respiratory 1.01 0.956 – 1.06 0.815 1689 16489 all phecode
509.8
Dependence on respirator [Ventilator] or
Dependence on respirator [Ventilator] or supplemental oxygen
 Respiratory 1.02 0.973 – 1.07 0.373 1741 17249 all phecode
510 Other diseases of lung Respiratory 1.02 0.99 – 1.05 0.204 5503 35907 all phecode
510.2 Lung transplant Respiratory 1.06 0.913 – 1.23 0.437 176 1757 all phecode
512 Other symptoms of respiratory system Respiratory 1.01 0.99 – 1.03 0.356 18621 28154 all phecode
512.1 Wheezing Respiratory 0.963 0.91 – 1.02 0.185 1409 13516 all phecode
512.2 Painful respiration Respiratory 1.01 0.967 – 1.06 0.65 2309 21263 all phecode
512.3 Abnormal chest sounds Respiratory 0.965 0.854 – 1.09 0.564 291 2845 all phecode
512.7 Shortness of breath Respiratory 1.02 0.998 – 1.05 0.0737 10034 28081 all phecode
512.8 Cough Respiratory 0.996 0.973 – 1.02 0.745 9501 28148 all phecode
512.9 Other dyspnea Respiratory 1.02 0.997 – 1.04 0.0878 10804 28104 all phecode
513 Respiratory abnormalities Respiratory 1.01 0.986 – 1.03 0.53 12932 33822 all phecode
513.3 Hypoventilation Respiratory 1 0.934 – 1.07 0.981 880 8646 all phecode
513.31 Apnea Respiratory 1.04 0.943 – 1.14 0.447 462 4607 all phecode
513.32 Orthopnea Respiratory 0.983 0.86 – 1.12 0.802 220 2160 all phecode
513.4 Hyperventilation Respiratory 1.05 0.963 – 1.16 0.25 515 5124 all phecode
513.8 Disorders of diaphragm Respiratory 0.995 0.874 – 1.13 0.938 258 2557 all phecode
514 Abnormal findings examination of lungs Respiratory 0.992 0.963 – 1.02 0.569 5365 34834 all phecode
514.1
Abnormal results of function study of pulmonary
Abnormal results of function study of pulmonary system
 Respiratory 1.02 0.895 – 1.15 0.809 258 2580 all phecode
514.2 Solitary pulmonary nodule Respiratory 0.981 0.945 – 1.02 0.334 3018 27338 all phecode
516 Abnormal sputum Respiratory 1.02 0.941 – 1.1 0.685 735 7332 all phecode
516.1 Hemoptysis Respiratory 1.02 0.938 – 1.11 0.627 611 6080 all phecode
519
Other diseases of respiratory system, not
Other diseases of respiratory system, not elsewhere classified
 Respiratory 1.01 0.983 – 1.04 0.478 6458 39057 all phecode
519.1 Tracheostomy complications Respiratory 0.997 0.864 – 1.15 0.967 214 2136 all phecode
519.2 Respiratory complications Respiratory 0.999 0.906 – 1.1 0.984 445 4430 all phecode
519.8 Other diseases of respiratory system, NEC Respiratory 0.969 0.92 – 1.02 0.24 1588 15787 all phecode
519.9
Symptoms involving respiratory system and other
Symptoms involving respiratory system and other chest symptoms
 Respiratory 1.02 0.99 – 1.05 0.194 4706 34489 all phecode
520 Disorders of tooth development Digestive 0.986 0.886 – 1.1 0.799 369 3690 all phecode
520.1 Hereditary disturbances in tooth structure Digestive 0.947 0.807 – 1.11 0.508 165 1642 all phecode
520.2 Disturbances in tooth eruption Digestive 1.02 0.89 – 1.18 0.745 218 2172 all phecode
521 Diseases of hard tissues of teeth Digestive 0.95 0.886 – 1.02 0.146 898 8954 all phecode
521.1 Dental caries Digestive 0.943 0.878 – 1.01 0.111 837 8349 all phecode
521.2 Dental abrasion, erosion and attrition Digestive 0.993 0.749 – 1.32 0.961 52 510 all phecode
522 Diseases of pulp and periapical tissues Digestive 1.03 0.942 – 1.13 0.511 535 5340 all phecode
522.5 Periapical abscess Digestive 1 0.908 – 1.1 0.982 459 4583 all phecode
523 Gingival and periodontal diseases Digestive 0.979 0.907 – 1.06 0.599 718 7180 all phecode
523.1 Gingivitis Digestive 0.842 0.708 – 1 0.0516 142 1418 all phecode
523.3 Periodontitis (acute or chronic) Digestive 1 0.902 – 1.12 0.941 364 3636 all phecode
523.31 Acute periodontitis Digestive 0.96 0.855 – 1.08 0.495 311 3109 all phecode
523.32 Chronic periodontitis Digestive 1.19 0.986 – 1.44 0.0697 122 1204 all phecode
524 Dentofacial anomalies, including malocclusion Digestive 0.998 0.895 – 1.11 0.975 363 3630 all phecode
524.3 Anomalies of tooth position/malocclusion Digestive 1.07 0.928 – 1.22 0.369 220 2200 all phecode
525
Other diseases of the teeth and supporting
Other diseases of the teeth and supporting structures
 Digestive 0.995 0.933 – 1.06 0.879 1039 10382 all phecode
525.1 Loss of teeth or edentulism Digestive 0.966 0.866 – 1.08 0.529 374 3731 all phecode
526 Diseases of the jaws Digestive 0.976 0.938 – 1.02 0.234 2680 26455 all phecode
526.1 Cysts of the jaws Digestive 0.979 0.858 – 1.12 0.756 247 2470 all phecode
526.3 Anomalies of jaw size/symmetry Digestive 0.93 0.815 – 1.06 0.278 241 2383 all phecode
526.4 Temporomandibular joint disorders Digestive 0.999 0.947 – 1.05 0.979 1504 15025 all phecode
526.41 Temporomandibular joint disorder, unspecified Digestive 0.996 0.938 – 1.06 0.903 1187 11858 all phecode
526.42 Arthralgia/ankylosis of temporomandibular joint Digestive 1 0.93 – 1.08 0.926 741 7400 all phecode
526.5 Inflammatory conditions of jaw Digestive 0.961 0.85 – 1.09 0.519 287 2864 all phecode
526.8 Exostosis of jaw Digestive 0.985 0.742 – 1.31 0.918 53 521 all phecode
526.9 Jaw disease NOS Digestive 0.963 0.877 – 1.06 0.428 487 4867 all phecode
527 Diseases of the salivary glands Digestive 0.982 0.934 – 1.03 0.457 1781 17771 all phecode
527.1 Hypertrophy of salivary gland Digestive 0.971 0.749 – 1.26 0.822 58 579 all phecode
527.2 Sialoadenitis Digestive 0.999 0.9 – 1.11 0.989 394 3936 all phecode
527.7 Disturbance of salivary secretion Digestive 1 0.936 – 1.07 0.975 952 9481 all phecode
527.8 Other specified diseases of the salivary glands Digestive 1.03 0.907 – 1.17 0.642 254 2540 all phecode
528
Diseases of the oral soft tissues, excluding
Diseases of the oral soft tissues, excluding lesions specific for gingiva and tongue
 Digestive 0.973 0.935 – 1.01 0.191 2643 26197 all phecode
528.1 Stomatitis and mucositis Digestive 0.927 0.856 – 1 0.061 668 6657 all phecode
528.11 Stomatitis and mucositis (ulcerative) Digestive 0.863 0.75 – 0.993 0.0392 211 2110 all phecode
528.12 Oral aphthae Digestive 0.953 0.83 – 1.09 0.495 215 2137 all phecode
528.3 Cellulitis and abscess of oral soft tissues Digestive 0.931 0.816 – 1.06 0.292 235 2338 all phecode
528.4 Cysts of oral soft tissues Digestive 1.09 0.907 – 1.3 0.365 124 1229 all phecode
528.41 Cyst of the salivary gland Digestive 0.953 0.759 – 1.2 0.681 77 760 all phecode
528.5 Diseases of lips Digestive 0.98 0.889 – 1.08 0.677 462 4602 all phecode
528.6 Leukoplakia of oral mucosa Digestive 0.945 0.793 – 1.13 0.524 137 1370 all phecode
528.7 Sialolithiasis Digestive 1.06 0.903 – 1.25 0.471 163 1623 all phecode
529 Diseases and other conditions of the tongue Digestive 1.03 0.949 – 1.11 0.516 690 6878 all phecode
529.1 Glossitis Digestive 1.05 0.883 – 1.25 0.571 129 1281 all phecode
529.6 Glossodynia Digestive 0.923 0.787 – 1.08 0.327 168 1652 all phecode
530 Diseases of esophagus Digestive 0.992 0.973 – 1.01 0.413 17081 27931 all phecode
530.1 Esophagitis, GERD and related diseases Digestive 0.993 0.973 – 1.01 0.478 16572 27931 all phecode
530.11 GERD Digestive 0.992 0.972 – 1.01 0.413 16143 27929 all phecode
530.12 Ulcer of esophagus Digestive 1.04 0.94 – 1.16 0.421 400 3983 all phecode
530.13 Barrett's esophagus Digestive 0.988 0.916 – 1.07 0.755 762 7584 all phecode
530.14 Reflux esophagitis Digestive 0.981 0.935 – 1.03 0.432 1900 17495 all phecode
530.15 Eosinophilic esophagitis Digestive 0.809 0.703 – 0.931 0.00313 221 2210 all phecode
530.2 Esophageal bleeding (varices/hemorrhage) Digestive 0.918 0.847 – 0.996 0.0394 651 6473 all phecode
530.3 Stricture and stenosis of esophagus Digestive 0.987 0.922 – 1.06 0.705 911 8971 all phecode
530.5 Disorders of esophageal motility Digestive 1.03 0.946 – 1.13 0.469 548 5432 all phecode
530.6 Diverticulum of esophagus, acquired Digestive 1.05 0.873 – 1.25 0.632 129 1265 all phecode
530.7 Gastroesophageal laceration-hemorrhage syndrome Digestive 0.703 0.556 – 0.889 0.00323 82 812 all phecode
530.9 Heartburn Digestive 0.973 0.923 – 1.03 0.317 1519 14928 all phecode
531 Peptic ulcer (excl. esophageal) Digestive 0.984 0.94 – 1.03 0.483 2073 20617 all phecode
531.1 Hemorrhage from gastrointestinal ulcer Digestive 1.01 0.907 – 1.11 0.917 391 3883 all phecode
531.2 Gastric ulcer Digestive 0.979 0.922 – 1.04 0.492 1201 11970 all phecode
531.3 Duodenal ulcer Digestive 0.957 0.871 – 1.05 0.367 467 4640 all phecode
531.4 Peptic ulcer, site unspecified Digestive 0.918 0.854 – 0.987 0.0214 804 8018 all phecode
531.5 Gastrojejunal ulcer Digestive 1.05 0.886 – 1.24 0.592 150 1500 all phecode
532 Dysphagia Digestive 0.984 0.956 – 1.01 0.287 5585 26852 all phecode
535 Gastritis and duodenitis Digestive 0.994 0.955 – 1.03 0.751 2799 27335 all phecode
535.1 Acute gastritis Digestive 0.994 0.935 – 1.06 0.846 1178 11750 all phecode
535.2 Atrophic gastritis Digestive 0.962 0.861 – 1.08 0.498 344 3413 all phecode
535.6 Duodenitis Digestive 0.943 0.844 – 1.05 0.304 334 3337 all phecode
535.8 Other specified gastritis Digestive 0.95 0.874 – 1.03 0.222 638 6354 all phecode
535.9 Gastritis and duodenitis, NOS Digestive 0.979 0.923 – 1.04 0.472 1255 12511 all phecode
536 Disorders of function of stomach Digestive 1.01 0.968 – 1.05 0.772 2911 27685 all phecode
536.3 Gastroparesis Digestive 1.04 0.963 – 1.13 0.309 706 6901 all phecode
536.7
Complications of gastrostomy, colostomy and
Complications of gastrostomy, colostomy and enterostomy
 Digestive 1.03 0.93 – 1.14 0.584 407 4059 all phecode
536.8
Dyspepsia and other specified disorders of
Dyspepsia and other specified disorders of function of stomach
 Digestive 0.988 0.944 – 1.03 0.596 2150 21094 all phecode
537 Other disorders of stomach and duodenum Digestive 0.991 0.955 – 1.03 0.634 3183 30048 all phecode
537.1 Lesions of stomach and duodenum Digestive 1.05 0.9 – 1.22 0.551 173 1725 all phecode
539 Bariatric surgery Digestive 0.937 0.889 – 0.988 0.017 1509 15074 all phecode
540 Appendiceal conditions Digestive 1 0.911 – 1.1 0.991 495 4948 all phecode
540.1 Appendicitis Digestive 0.987 0.894 – 1.09 0.793 425 4239 all phecode
540.11 Acute appendicitis Digestive 1.02 0.911 – 1.13 0.779 353 3511 all phecode
550 Abdominal hernia Digestive 0.993 0.968 – 1.02 0.622 6768 37731 all phecode
550.1 Inguinal hernia Digestive 0.973 0.926 – 1.02 0.277 1744 16488 all phecode
550.2 Diaphragmatic hernia Digestive 1.01 0.968 – 1.05 0.753 2817 25849 all phecode
550.3 Femoral hernia Digestive 0.974 0.815 – 1.16 0.77 131 1291 all phecode
550.4 Umbilical hernia Digestive 0.962 0.908 – 1.02 0.182 1313 13110 all phecode
550.5 Ventral hernia Digestive 0.98 0.938 – 1.02 0.369 2241 22163 all phecode
550.6 Incisional hernia Digestive 0.956 0.903 – 1.01 0.119 1313 13111 all phecode
555
Inflammatory bowel disease and other
Inflammatory bowel disease and other gastroenteritis and colitis
 Digestive 1.01 0.961 – 1.07 0.607 1536 15153 all phecode
555.1 Regional enteritis Digestive 1.01 0.942 – 1.08 0.799 919 9095 all phecode
555.2 Ulcerative colitis Digestive 1.01 0.944 – 1.08 0.755 937 9315 all phecode
555.21 Ulcerative colitis (chronic) Digestive 1.04 0.95 – 1.14 0.401 537 5315 all phecode
556 Ulceration of the lower GI tract Digestive 0.989 0.91 – 1.07 0.789 632 6267 all phecode
556.1 Ulceration of intestine Digestive 0.985 0.901 – 1.08 0.744 551 5451 all phecode
556.11
Angiodysplasia of intestine (without mention of
Angiodysplasia of intestine (without mention of hemorrhage)
 Digestive 0.973 0.844 – 1.12 0.705 214 2093 all phecode
557 Intestinal malabsorption (non-celiac) Digestive 0.972 0.924 – 1.02 0.276 1716 16490 all phecode
557.1 Celiac disease Digestive 0.95 0.859 – 1.05 0.315 421 4026 all phecode
558 Noninfectious gastroenteritis Digestive 1.01 0.97 – 1.04 0.76 3458 26408 all phecode
559 Ileostomy status Digestive 0.991 0.926 – 1.06 0.787 957 9565 all phecode
560 Intestinal obstruction without mention of hernia Digestive 0.994 0.956 – 1.03 0.744 3004 24851 all phecode
560.1 Paralytic ileus Digestive 1.02 0.969 – 1.07 0.449 1627 15714 all phecode
560.2 Impaction of intestine Digestive 0.901 0.81 – 1 0.0562 387 3779 all phecode
560.3 Peritoneal or intestinal adhesions Digestive 0.957 0.844 – 1.08 0.49 266 2647 all phecode
560.4 Other intestinal obstruction Digestive 0.98 0.931 – 1.03 0.442 1651 16170 all phecode
561 Symptoms involving digestive system Digestive 0.957 0.918 – 0.997 0.0369 2608 21766 all phecode
562 Diverticulosis and diverticulitis Digestive 0.992 0.964 – 1.02 0.589 6295 23431 all phecode
562.1 Diverticulosis Digestive 0.992 0.964 – 1.02 0.607 6246 23383 all phecode
562.2 Diverticulitis Digestive 0.965 0.917 – 1.02 0.183 1611 15162 all phecode
564 Functional digestive disorders Digestive 1 0.98 – 1.02 0.844 11411 28676 all phecode
564.1 Irritable Bowel Syndrome Digestive 1 0.965 – 1.04 0.963 3457 22266 all phecode
564.9 Personal history of diseases of digestive system Digestive 0.987 0.95 – 1.03 0.506 3074 25861 all phecode
565 Anal and rectal conditions Digestive 1.02 0.986 – 1.06 0.235 3355 30757 all phecode
565.1 Anal and rectal polyp Digestive 1.02 0.96 – 1.08 0.57 1305 12649 all phecode
567 Peritonitis and retroperitoneal infections Digestive 0.997 0.943 – 1.05 0.927 1364 13616 all phecode
568 Other disorders of peritoneum Digestive 0.971 0.924 – 1.02 0.244 1705 17038 all phecode
568.1
Peritoneal adhesions (postoperative)
Peritoneal adhesions (postoperative) (postinfection)
 Digestive 0.946 0.892 – 1 0.0636 1247 12468 all phecode
569 Other disorders of intestine Digestive 1.01 0.985 – 1.04 0.435 8079 35231 all phecode
569.1 Toxic gastroenteritis and colitis Digestive 1.1 0.98 – 1.24 0.104 326 3260 all phecode
569.2 Gastrointestinal complications Digestive 0.962 0.911 – 1.02 0.173 1395 13933 all phecode
571 Chronic liver disease and cirrhosis Digestive 1.02 0.987 – 1.05 0.251 4610 32562 all phecode
571.5 Other chronic nonalcoholic liver disease Digestive 1.01 0.981 – 1.05 0.413 4342 32234 all phecode
571.51 Cirrhosis of liver without mention of alcohol Digestive 0.994 0.932 – 1.06 0.865 1018 10095 all phecode
571.6 Primary biliary cirrhosis Digestive 0.989 0.849 – 1.15 0.892 179 1790 all phecode
571.8
Liver abscess and sequelae of chronic liver
Liver abscess and sequelae of chronic liver disease
 Digestive 1.03 0.965 – 1.1 0.368 950 9498 all phecode
571.81 Portal hypertension Digestive 0.99 0.909 – 1.08 0.814 573 5730 all phecode
572 Ascites (non malignant) Digestive 0.972 0.931 – 1.01 0.196 2278 22675 all phecode
573 Other disorders of liver Digestive 1.02 0.99 – 1.05 0.196 5599 33620 all phecode
573.1 Chronic passive congestion of liver Digestive 0.885 0.735 – 1.07 0.198 136 1359 all phecode
573.2 Liver replaced by transplant Digestive 0.998 0.884 – 1.13 0.975 292 2920 all phecode
573.3 Hepatomegaly Digestive 0.976 0.887 – 1.07 0.621 470 4700 all phecode
573.4 Acute and subacute necrosis of liver Digestive 1.07 0.951 – 1.2 0.268 316 3149 all phecode
573.5 Jaundice (not of newborn) Digestive 1.01 0.944 – 1.08 0.799 958 9496 all phecode
573.6
Nonspecific elevation of levels of transaminase
Nonspecific elevation of levels of transaminase or lactic acid dehydrogenase [LDH]
 Digestive 1.02 0.976 – 1.06 0.453 2756 26470 all phecode
573.7 Abnormal results of function study of liver Digestive 1.01 0.971 – 1.05 0.667 3018 27774 all phecode
573.9 Abnormal serum enzyme levels Digestive 1.03 0.998 – 1.06 0.0644 4679 33866 all phecode
574 Cholelithiasis and cholecystitis Digestive 0.985 0.949 – 1.02 0.409 3177 30809 all phecode
574.1 Cholelithiasis Digestive 0.979 0.942 – 1.02 0.276 2924 28874 all phecode
574.11 Cholelithiasis with acute cholecystitis Digestive 0.93 0.831 – 1.04 0.199 342 3412 all phecode
574.12 Cholelithiasis with other cholecystitis Digestive 0.998 0.915 – 1.09 0.968 553 5501 all phecode
574.2 Calculus of bile duct Digestive 0.964 0.898 – 1.03 0.311 852 8503 all phecode
574.3 Cholecystitis without cholelithiasis Digestive 0.973 0.905 – 1.05 0.457 822 8181 all phecode
575 Other biliary tract disease Digestive 0.968 0.927 – 1.01 0.149 2266 22555 all phecode
575.1 Cholangitis Digestive 1.01 0.908 – 1.13 0.823 354 3530 all phecode
575.2 Obstruction of bile duct Digestive 0.979 0.9 – 1.06 0.622 621 6201 all phecode
575.6 Cholesterolosis of gallbladder Digestive 1.02 0.886 – 1.18 0.764 207 2063 all phecode
575.7 Other disorders of gallbladder Digestive 0.936 0.875 – 1 0.0541 939 9382 all phecode
575.8 Other disorders of biliary tract Digestive 0.959 0.903 – 1.02 0.179 1154 11523 all phecode
575.9
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of biliary tract
 Digestive 0.921 0.81 – 1.05 0.211 260 2600 all phecode
577 Diseases of pancreas Digestive 0.973 0.931 – 1.02 0.218 2225 22106 all phecode
577.1 Acute pancreatitis Digestive 0.953 0.898 – 1.01 0.109 1212 12110 all phecode
577.2 Chronic pancreatitis Digestive 0.912 0.832 – 1 0.0508 495 4950 all phecode
577.3 Cyst and pseudocyst of pancreas Digestive 0.952 0.872 – 1.04 0.267 570 5601 all phecode
578 Gastrointestinal hemorrhage Digestive 1.01 0.975 – 1.04 0.733 4554 37045 all phecode
578.1 Hematemesis Digestive 0.998 0.907 – 1.1 0.973 485 4842 all phecode
578.2 Blood in stool Digestive 0.986 0.948 – 1.03 0.497 2743 26554 all phecode
578.8 Hemorrhage of rectum and anus Digestive 1.02 0.976 – 1.07 0.379 2210 21750 all phecode
578.9 Hemorrhage of gastrointestinal tract Digestive 0.982 0.932 – 1.03 0.499 1562 15345 all phecode
579 Other symptoms involving abdomen and pelvis Digestive 0.983 0.953 – 1.01 0.299 4431 34209 all phecode
579.2 Splenomegaly Digestive 1 0.927 – 1.08 0.972 730 7262 all phecode
579.8 Nonspecific abnormal findings in stool contents Digestive 0.993 0.94 – 1.05 0.815 1410 13877 all phecode
580 Nephritis; nephrosis; renal sclerosis Genitourinary 0.998 0.95 – 1.05 0.927 1881 15516 all phecode
580.1 Glomerulonephritis Genitourinary 0.986 0.887 – 1.1 0.792 401 3992 all phecode
580.11 Proliferative glomerulonephritis Genitourinary 0.965 0.813 – 1.15 0.682 146 1440 all phecode
580.12 Non-proliferative glomerulonephritis Genitourinary 0.961 0.784 – 1.18 0.697 114 1128 all phecode
580.13 Acute glomerulonephritis, NOS Genitourinary 1.03 0.786 – 1.34 0.842 61 600 all phecode
580.14 Chronic glomerulonephritis, NOS Genitourinary 0.991 0.872 – 1.13 0.888 277 2760 all phecode
580.2
Nephrotic syndrome without mention of
Nephrotic syndrome without mention of glomerulonephritis
 Genitourinary 1.03 0.891 – 1.18 0.715 221 2193 all phecode
580.3
Nephritis and nephropathy without mention of
Nephritis and nephropathy without mention of glomerulonephritis
 Genitourinary 1.01 0.954 – 1.06 0.78 1502 11930 all phecode
580.31
Nephritis and nephropathy in diseases
Nephritis and nephropathy in diseases classified elsewhere
 Genitourinary 0.992 0.927 – 1.06 0.811 992 7228 all phecode
580.32
Nephritis and nephropathy with pathological
Nephritis and nephropathy with pathological lesion
 Genitourinary 1.03 0.954 – 1.12 0.422 683 6612 all phecode
580.4 Renal sclerosis, NOS Genitourinary 0.981 0.877 – 1.1 0.733 340 3400 all phecode
585 Renal failure Genitourinary 0.993 0.967 – 1.02 0.591 7470 32340 all phecode
585.1 Acute renal failure Genitourinary 0.999 0.966 – 1.03 0.937 4265 27230 all phecode
585.2 Renal failure NOS Genitourinary 0.954 0.887 – 1.03 0.199 832 8162 all phecode
585.3 Chronic renal failure [CKD] Genitourinary 0.997 0.968 – 1.03 0.844 5580 29470 all phecode
585.31 Renal dialysis Genitourinary 0.912 0.845 – 0.984 0.0175 747 7423 all phecode
585.32 End stage renal disease Genitourinary 0.959 0.898 – 1.02 0.207 1007 9783 all phecode
585.33 Chronic Kidney Disease, Stage III Genitourinary 1.01 0.971 – 1.05 0.662 3209 21312 all phecode
585.34 Chronic Kidney Disease, Stage IV Genitourinary 0.979 0.916 – 1.05 0.534 977 9190 all phecode
585.4 Chronic kidney disease, Stage I or II Genitourinary 1.01 0.948 – 1.07 0.857 1227 11191 all phecode
586 Other disorders of the kidney and ureters Genitourinary 1.01 0.984 – 1.04 0.481 7628 34189 all phecode
586.1 Anatomical abnormatilies of kidney and ureters Genitourinary 0.975 0.874 – 1.09 0.643 349 3480 all phecode
586.11 Small kidney Genitourinary 1.01 0.873 – 1.16 0.925 210 2093 all phecode
586.12 Vesicoureteral reflux Genitourinary 0.901 0.758 – 1.07 0.235 136 1360 all phecode
586.2 Cyst of kidney, acquired Genitourinary 0.987 0.934 – 1.04 0.65 1381 12912 all phecode
586.3 Vascular disorders of kidney/hypertrophy Genitourinary 1.04 0.899 – 1.21 0.58 187 1862 all phecode
586.4 Stricture/obstruction of ureter Genitourinary 0.959 0.913 – 1.01 0.0857 1821 17115 all phecode
587 Kidney replaced by transpant Genitourinary 0.931 0.865 – 1 0.0525 819 8134 all phecode
588 Disorders resulting from impaired renal function Genitourinary 0.973 0.911 – 1.04 0.43 976 9389 all phecode
588.1 Renal osteodystrophy Genitourinary 1.03 0.916 – 1.16 0.608 290 2900 all phecode
588.2 Secondary hyperparathyroidism (of renal origin) Genitourinary 0.983 0.911 – 1.06 0.658 755 7275 all phecode
589 Abnormal results of function study of kidney Genitourinary 0.987 0.925 – 1.05 0.695 1007 9834 all phecode
590 Pyelonephritis Genitourinary 0.987 0.935 – 1.04 0.636 1461 14350 all phecode
591 Urinary tract infection Genitourinary 0.996 0.973 – 1.02 0.717 9873 32513 all phecode
592 Cystitis and urethritis Genitourinary 1 0.966 – 1.04 0.852 3038 24207 all phecode
592.1 Cystitis Genitourinary 1.01 0.968 – 1.05 0.735 2880 23279 all phecode
592.11 Acute cystitis Genitourinary 1 0.954 – 1.05 0.929 1783 16452 all phecode
592.12 Chronic cystitis Genitourinary 0.982 0.861 – 1.12 0.783 239 2343 all phecode
592.13 Chronic interstitial cystitis Genitourinary 1.01 0.917 – 1.12 0.799 431 4310 all phecode
592.2 Urethritis and urethral syndrome Genitourinary 1.02 0.885 – 1.18 0.768 210 2093 all phecode
593 Hematuria Genitourinary 1.02 0.986 – 1.05 0.297 4859 32063 all phecode
593.1 Gross hematuria Genitourinary 0.979 0.929 – 1.03 0.413 1585 14824 all phecode
593.2 Microscopic hematuria Genitourinary 1.07 1 – 1.14 0.0457 1049 10301 all phecode
594 Urinary calculus Genitourinary 1 0.976 – 1.03 0.857 6707 38209 all phecode
594.1 Calculus of kidney Genitourinary 1.01 0.979 – 1.03 0.686 6273 38051 all phecode
594.2 Calculus of lower urinary tract Genitourinary 1.09 0.979 – 1.21 0.118 366 3638 all phecode
594.3 Calculus of ureter Genitourinary 1.01 0.954 – 1.07 0.755 1361 13561 all phecode
594.8 Renal colic Genitourinary 1.08 0.966 – 1.2 0.182 356 3560 all phecode
595 Hydronephrosis Genitourinary 0.964 0.916 – 1.01 0.15 1670 16658 all phecode
596 Other disorders of bladder Genitourinary 0.999 0.962 – 1.04 0.942 3074 28020 all phecode
596.1 Bladder neck obstruction Genitourinary 0.928 0.835 – 1.03 0.167 400 3942 all phecode
596.5 Functional disorders of bladder Genitourinary 0.984 0.937 – 1.03 0.534 1719 17049 all phecode
597 Other disorders of urethra and urinary tract Genitourinary 1.01 0.948 – 1.07 0.831 1211 11998 all phecode
597.1 Urethral stricture (not specified as infectious) Genitourinary 0.973 0.897 – 1.06 0.514 661 6537 all phecode
597.2 Urinary complications NEC Genitourinary 0.965 0.905 – 1.03 0.28 1049 10479 all phecode
597.8 Urethral hypermobility/ISD Genitourinary 0.939 0.809 – 1.09 0.403 189 1873 all phecode
598 Abnormal findings on examination of urine Genitourinary 1.03 0.867 – 1.22 0.749 138 1356 all phecode
598.4 Other cells and casts in urine Genitourinary 1.07 0.89 – 1.28 0.486 122 1192 all phecode
599 Other symptoms/disorders or the urinary system Genitourinary 1.01 0.986 – 1.03 0.516 14168 30681 all phecode
599.1 Urinary obstruction Genitourinary 0.877 0.812 – 0.947 0.000798 728 6861 all phecode
599.2 Retention of urine Genitourinary 1 0.973 – 1.03 0.838 5034 28305 all phecode
599.3 Dysuria Genitourinary 1.01 0.974 – 1.04 0.717 4397 27849 all phecode
599.4 Urinary incontinence Genitourinary 1.02 0.987 – 1.05 0.29 5599 26960 all phecode
599.5 Frequency of urination and polyuria Genitourinary 1.01 0.982 – 1.04 0.452 5498 28723 all phecode
599.6 Oliguria and anuria Genitourinary 0.963 0.885 – 1.05 0.379 599 5902 all phecode
599.7 Urethral discharge Genitourinary 1.05 0.87 – 1.26 0.629 118 1175 all phecode
599.8 Other symptoms involving urinary system Genitourinary 1.01 0.977 – 1.04 0.656 5446 27963 all phecode
599.9 Other abnormality of urination Genitourinary 0.996 0.959 – 1.03 0.828 3041 24877 all phecode
600 Hyperplasia of prostate Genitourinary 0.996 0.959 – 1.04 0.853 4063 11364 all phecode
601 Inflammatory diseases of prostate Genitourinary 0.954 0.894 – 1.02 0.145 1044 9665 all phecode
601.1 Prostatitis Genitourinary 0.964 0.877 – 1.06 0.453 477 4596 all phecode
601.11 Acute prostatitis Genitourinary 1.13 0.93 – 1.37 0.22 124 1200 all phecode
601.12 Chronic prostatitis Genitourinary 0.91 0.738 – 1.12 0.38 95 943 all phecode
601.3 Orchitis and epididymitis Genitourinary 0.982 0.883 – 1.09 0.73 389 3822 all phecode
601.4 Balanoposthitis Genitourinary 0.896 0.749 – 1.07 0.227 127 1224 all phecode
601.8
Other inflammatory disorders of male genital
Other inflammatory disorders of male genital organs
 Genitourinary 0.931 0.789 – 1.1 0.394 161 1591 all phecode
602 Other disorders of prostate Genitourinary 0.968 0.869 – 1.08 0.555 361 3399 all phecode
602.3 Dysplasia of prostate Genitourinary 0.892 0.705 – 1.13 0.341 77 730 all phecode
603 Other disorders of testis Genitourinary 0.921 0.835 – 1.02 0.0994 440 4354 all phecode
603.1 Hydrocele Genitourinary 0.846 0.75 – 0.955 0.00693 293 2882 all phecode
603.2 Spermatocele Genitourinary 1.01 0.859 – 1.19 0.901 156 1539 all phecode
604 Disorders of penis Genitourinary 0.936 0.866 – 1.01 0.1 685 6748 all phecode
604.1 Redundant prepuce and phimosis/BXO Genitourinary 0.951 0.808 – 1.12 0.549 155 1540 all phecode
604.3 Peyronie's disease Genitourinary 0.967 0.838 – 1.12 0.642 215 2132 all phecode
605 Erectile dysfunction [ED] Genitourinary 0.998 0.961 – 1.04 0.901 3776 12700 all phecode
608 Other disorders of male genital organs Genitourinary 1 0.95 – 1.05 0.983 1645 13758 all phecode
609 Male infertility and abnormal spermatozoa Genitourinary 0.918 0.83 – 1.02 0.099 424 4196 all phecode
609.1 Infertility, male Genitourinary 0.9 0.798 – 1.02 0.0887 302 2992 all phecode
609.11 Azoospermia and oligospermia Genitourinary 0.792 0.64 – 0.981 0.0323 95 950 all phecode
609.2 Abnormal spermatozoa Genitourinary 0.987 0.842 – 1.16 0.87 154 1519 all phecode
610 Benign mammary dysplasias Genitourinary 1 0.965 – 1.04 0.985 3683 16548 all phecode
610.1 Cystic mastopathy Genitourinary 0.987 0.937 – 1.04 0.617 1633 14191 all phecode
610.2 Fibroadenosis of breast Genitourinary 0.858 0.663 – 1.11 0.245 60 600 all phecode
610.4 Benign neoplasm of breast Genitourinary 1.01 0.968 – 1.05 0.705 2837 16430 all phecode
610.8 Other specified benign mammary dysplasias Genitourinary 0.999 0.942 – 1.06 0.967 1269 12191 all phecode
611 Abnormal findings on mammogram or breast exam Genitourinary 1.02 0.987 – 1.05 0.274 6067 18690 all phecode
611.1 Abnormal mammogram Genitourinary 1.01 0.976 – 1.04 0.627 4980 16120 all phecode
611.11 Mammographic microcalcification Genitourinary 1.04 0.974 – 1.1 0.264 1122 10394 all phecode
611.3 Lump or mass in breast Genitourinary 1.01 0.975 – 1.05 0.558 3549 18572 all phecode
612
Breast conditions, congenital or relating to
Breast conditions, congenital or relating to hormones
 Genitourinary 1.01 0.947 – 1.08 0.756 1051 10425 all phecode
612.1 Galactorrhea Genitourinary 1.11 0.931 – 1.32 0.248 139 1390 all phecode
612.2 Hypertrophy of breast (Gynecomastia) Genitourinary 1.01 0.941 – 1.09 0.732 800 7962 all phecode
612.3 Congenital anomalies of breast Genitourinary 0.806 0.643 – 1.01 0.0617 83 810 all phecode
613 Other nonmalignant breast conditions Genitourinary 1.01 0.976 – 1.05 0.546 3897 22072 all phecode
613.1 Inflammatory disease of breast Genitourinary 0.972 0.892 – 1.06 0.524 593 5874 all phecode
613.5 Mastodynia Genitourinary 1 0.954 – 1.06 0.883 1675 16203 all phecode
613.7 Other signs and symptoms in breast Genitourinary 0.989 0.922 – 1.06 0.767 883 8754 all phecode
613.8 Other specified disorders of breast Genitourinary 1.04 0.968 – 1.11 0.309 932 9248 all phecode
613.9 Breast disorder NOS Genitourinary 0.996 0.943 – 1.05 0.889 1465 14174 all phecode
614 Inflammatory diseases of female pelvic organs Genitourinary 0.999 0.964 – 1.03 0.94 3715 19647 all phecode
614.1
Pelvic peritoneal adhesions, female
Pelvic peritoneal adhesions, female (postoperative) (postinfection)
 Genitourinary 1.01 0.904 – 1.13 0.841 337 3370 all phecode
614.3 Pelvic inflammatory disease (PID) Genitourinary 1.04 0.947 – 1.15 0.391 478 4773 all phecode
614.31 Acute inflammatory pelvic disease Genitourinary 1.03 0.823 – 1.28 0.815 94 933 all phecode
614.32 Chronic inflammatory pelvic disease Genitourinary 1.06 0.906 – 1.23 0.481 186 1842 all phecode
614.33 Pelvic inflammatory disease, NOS Genitourinary 1.08 0.944 – 1.24 0.264 246 2460 all phecode
614.4 Inflammatory diseases of uterus, except cervix Genitourinary 1.01 0.864 – 1.18 0.884 165 1639 all phecode
614.5
Inflammatory disease of cervix, vagina, and
Inflammatory disease of cervix, vagina, and vulva
 Genitourinary 0.994 0.957 – 1.03 0.765 3180 19539 all phecode
614.51 Cervicitis and endocervicitis Genitourinary 1.02 0.899 – 1.16 0.771 264 2640 all phecode
614.52 Vaginitis and vulvovaginitis Genitourinary 0.988 0.949 – 1.03 0.562 2732 18924 all phecode
614.53 Cyst or abscess of Bartholin's gland Genitourinary 1.05 0.874 – 1.25 0.619 132 1311 all phecode
614.54 Abscess or ulceration of vulva Genitourinary 0.924 0.806 – 1.06 0.256 225 2244 all phecode
615 Endometriosis Genitourinary 0.99 0.939 – 1.04 0.695 1585 14666 all phecode
618 Genital prolapse Genitourinary 1.01 0.967 – 1.06 0.611 2079 17915 all phecode
618.1 Prolapse of vaginal walls Genitourinary 1.01 0.957 – 1.07 0.687 1408 13456 all phecode
618.2 Uterine/Uterovaginal prolapse Genitourinary 0.979 0.897 – 1.07 0.643 542 5390 all phecode
618.5 Prolapse of vaginal vault after hysterectomy Genitourinary 1.11 0.985 – 1.24 0.0868 317 3162 all phecode
618.6 Vaginal enterocele, congenital or acquired Genitourinary 0.968 0.877 – 1.07 0.525 441 4394 all phecode
619 Noninflammatory female genital disorders Genitourinary 0.983 0.953 – 1.01 0.25 5728 18687 all phecode
619.1
Noninflammatory disorders of ovary, fallopian
Noninflammatory disorders of ovary, fallopian tube, and broad ligament
 Genitourinary 0.945 0.89 – 1 0.0606 1233 12082 all phecode
619.2 Disorders of uterus, NEC Genitourinary 1.03 0.948 – 1.12 0.47 591 5897 all phecode
619.3 Noninflammatory disorders of cervix Genitourinary 0.953 0.867 – 1.05 0.32 483 4823 all phecode
619.4 Noninflammatory disorders of vagina Genitourinary 0.976 0.935 – 1.02 0.253 2525 18404 all phecode
619.5 Noninflammatory disorders of vulva and perineum Genitourinary 1.01 0.955 – 1.08 0.649 1189 11717 all phecode
620 Dysplasia of female genital organs Genitourinary 0.913 0.823 – 1.01 0.083 395 3950 all phecode
620.1 Dysplasia of cervix Genitourinary 0.895 0.768 – 1.04 0.156 178 1780 all phecode
621 Endometrial hyperplasia Genitourinary 0.898 0.813 – 0.992 0.0342 437 4370 all phecode
622 Polyp of female genital organs Genitourinary 0.969 0.917 – 1.02 0.257 1449 14264 all phecode
622.1 Polyp of corpus uteri Genitourinary 0.967 0.909 – 1.03 0.282 1132 11189 all phecode
622.2 Mucous polyp of cervix Genitourinary 0.952 0.862 – 1.05 0.329 445 4444 all phecode
623 Hypertrophy of female genital organs Genitourinary 0.973 0.905 – 1.05 0.452 824 8165 all phecode
624 Symptoms involving female genital tract Genitourinary 0.972 0.918 – 1.03 0.327 1348 12518 all phecode
624.1 Dystrophy of female genital tract Genitourinary 1 0.87 – 1.15 0.973 216 2155 all phecode
624.2 Atrophy of female genital tract Genitourinary 0.841 0.652 – 1.08 0.181 64 615 all phecode
624.9 stress incontinence, female Genitourinary 0.989 0.943 – 1.04 0.653 1935 15408 all phecode
625
Pain and other symptoms associated with female
Pain and other symptoms associated with female genital organs
 Genitourinary 0.984 0.955 – 1.01 0.304 5653 17303 all phecode
625.1 Dyspareunia Genitourinary 0.995 0.939 – 1.06 0.87 1267 12474 all phecode
626
Disorders of menstruation and other abnormal
Disorders of menstruation and other abnormal bleeding from female genital tract
 Genitourinary 0.973 0.943 – 1 0.0848 5940 15585 all phecode
626.1 Irregular menstrual cycle/bleeding Genitourinary 0.97 0.936 – 1 0.0869 4315 14604 all phecode
626.11 Absent or infrequent menstruation Genitourinary 0.995 0.933 – 1.06 0.878 1062 8531 all phecode
626.12 Excessive or frequent menstruation Genitourinary 0.953 0.909 – 0.999 0.0449 2097 11991 all phecode
626.13 Irregular menstrual cycle Genitourinary 0.971 0.925 – 1.02 0.243 1957 12265 all phecode
626.14 Irregular menstrual bleeding Genitourinary 0.947 0.886 – 1.01 0.107 970 8996 all phecode
626.15 Infertility, female, associated with anovulation Genitourinary 0.95 0.855 – 1.06 0.342 394 3789 all phecode
626.2 Dysmenorrhea Genitourinary 0.975 0.921 – 1.03 0.391 1373 9857 all phecode
626.4 Premenstrual tension syndromes Genitourinary 0.968 0.864 – 1.08 0.572 336 3308 all phecode
626.8 Infertility, female Genitourinary 1.01 0.934 – 1.08 0.894 817 6741 all phecode
627 Menopausal and postmenopausal disorders Genitourinary 0.972 0.94 – 1.01 0.101 4560 14557 all phecode
627.1 Postmenopausal bleeding Genitourinary 0.965 0.907 – 1.03 0.267 1146 10338 all phecode
627.2 Symptomatic menopause Genitourinary 0.976 0.938 – 1.02 0.238 3017 13763 all phecode
627.21 Symptomatic artificial menopause Genitourinary 1.11 0.934 – 1.31 0.244 152 1514 all phecode
627.22
Need for Hormone replacement therapy
Need for Hormone replacement therapy (postmenopausal)
 Genitourinary 0.964 0.864 – 1.08 0.514 356 3513 all phecode
627.3 Postmenopausal atrophic vaginitis Genitourinary 0.957 0.896 – 1.02 0.192 997 9484 all phecode
627.4 Premenopausal menorrhagia Genitourinary 0.937 0.84 – 1.04 0.242 361 3580 all phecode
627.5 Premature menopause and other ovarian failure Genitourinary 0.871 0.774 – 0.982 0.0237 309 3082 all phecode
628 Ovarian cyst Genitourinary 0.975 0.929 – 1.02 0.311 1945 13838 all phecode
634 Miscarriage; stillbirth Pregnancy Complications 1.01 0.943 – 1.09 0.719 826 8047 all phecode
634.1 Missed abortion/Hydatidiform mole Pregnancy Complications 0.985 0.869 – 1.12 0.821 273 2715 all phecode
634.3 Ectopic pregnancy Pregnancy Complications 1.04 0.86 – 1.25 0.716 117 1170 all phecode
635
Hemorrhage during pregnancy; childbirth and
Hemorrhage during pregnancy; childbirth and postpartum
 Pregnancy Complications 1.02 0.939 – 1.12 0.582 563 5309 all phecode
635.2
Antepartum hemorrhage, abruptio placentae, and
Antepartum hemorrhage, abruptio placentae, and placenta previa
 Pregnancy Complications 1.02 0.914 – 1.13 0.752 370 3629 all phecode
635.3 Placenta previa and abruptio placenta Pregnancy Complications 0.985 0.873 – 1.11 0.807 288 2850 all phecode
636
Early or threatened labor; hemorrhage in early
Early or threatened labor; hemorrhage in early pregnancy
 Pregnancy Complications 1.02 0.955 – 1.09 0.588 1080 7870 all phecode
636.1 Threatened premature labor Pregnancy Complications 0.941 0.847 – 1.05 0.256 380 3799 all phecode
636.2 Early onset of delivery Pregnancy Complications 0.917 0.814 – 1.03 0.157 288 2868 all phecode
636.3 Hemorrhage in early pregnancy Pregnancy Complications 1.07 0.972 – 1.18 0.165 441 4365 all phecode
636.8 Cervical incompetence Pregnancy Complications 0.843 0.669 – 1.06 0.145 77 770 all phecode
637
Short gestation; low birth weight; and fetal
Short gestation; low birth weight; and fetal growth retardation
 Pregnancy Complications 1.02 0.82 – 1.28 0.836 85 850 all phecode
642
Hypertension complicating pregnancy
Hypertension complicating pregnancy, childbirth, and the puerperium
 Pregnancy Complications 1.03 0.941 – 1.12 0.569 585 5725 all phecode
642.1 Preeclampsia and eclampsia Pregnancy Complications 1.02 0.908 – 1.15 0.71 302 3013 all phecode
643 Excessive vomiting in pregnancy Pregnancy Complications 1.02 0.897 – 1.16 0.758 252 2506 all phecode
643.1 Hyperemesis gravidarum Pregnancy Complications 0.993 0.823 – 1.2 0.946 119 1190 all phecode
644 Anemia during pregnancy Pregnancy Complications 0.972 0.848 – 1.11 0.68 224 2224 all phecode
646 Other complications of pregnancy NEC Pregnancy Complications 1.01 0.939 – 1.08 0.804 855 6531 all phecode
647
Infectious and parasitic complications
Infectious and parasitic complications affecting pregnancy
 Pregnancy Complications 0.978 0.849 – 1.13 0.753 211 2093 all phecode
647.1
Infections of genitourinary tract during
Infections of genitourinary tract during pregnancy
 Pregnancy Complications 0.916 0.797 – 1.05 0.219 222 2213 all phecode
647.3 Major puerperal infection Pregnancy Complications 1.01 0.787 – 1.28 0.967 65 650 all phecode
649
Other conditions or status of the mother
Other conditions or status of the mother complicating pregnancy, childbirth, or the puerperium
 Pregnancy Complications 1.04 0.978 – 1.1 0.217 1275 8010 all phecode
649.1
Diabetes or abnormal glucose tolerance
Diabetes or abnormal glucose tolerance complicating pregnancy
 Pregnancy Complications 1.08 0.997 – 1.18 0.0592 649 5687 all phecode
653
Problems associated with amniotic cavity and
Problems associated with amniotic cavity and membranes
 Pregnancy Complications 1.05 0.966 – 1.15 0.245 587 5463 all phecode
654.1
Abnormality of organs and soft tissues of
Abnormality of organs and soft tissues of pelvis complicating pregnancy, childbirth, or the puerperium
 Pregnancy Complications 1.13 0.984 – 1.31 0.0815 207 2055 all phecode
654.2 Rhesus isoimmunization in pregnancy Pregnancy Complications 1.13 0.975 – 1.3 0.107 204 2040 all phecode
655
Known or suspected fetal abnormality affecting
Known or suspected fetal abnormality affecting management of mother
 Pregnancy Complications 1.07 1.01 – 1.12 0.0195 1624 10064 all phecode
655.1 Abnormality in fetal heart rate or rhythm Pregnancy Complications 1.07 0.983 – 1.16 0.12 616 5533 all phecode
656 Other perinatal conditions of fetus or newborn Pregnancy Complications 1.01 0.94 – 1.08 0.83 898 7014 all phecode
656.2 Respiratory conditions of fetus and newborn Pregnancy Complications 0.821 0.631 – 1.07 0.14 66 660 all phecode
669 Complications of labor and delivery NEC Pregnancy Complications 1.03 0.961 – 1.11 0.395 887 6802 all phecode
671
Venous/cerebrovascular complications embolism
Venous/cerebrovascular complications embolism in pregnancy and the puerperium
 Pregnancy Complications 1.01 0.88 – 1.15 0.929 236 2351 all phecode
674 Other complications of the puerperium NEC Pregnancy Complications 0.995 0.841 – 1.18 0.95 158 1580 all phecode
676
Other disorders of the breast associated with
Other disorders of the breast associated with childbirth and disorders of lactation
 Pregnancy Complications 0.99 0.849 – 1.15 0.897 184 1814 all phecode
681 Superficial cellulitis and abscess Dermatologic 1 0.978 – 1.03 0.762 6500 38394 all phecode
681.1 Cellulitis and abscess of fingers/toes Dermatologic 1.01 0.956 – 1.08 0.63 1256 11462 all phecode
681.2 Cellulitis and abscess of face/neck Dermatologic 0.996 0.933 – 1.06 0.898 1007 9981 all phecode
681.3 Cellulitis and abscess of arm/hand Dermatologic 0.974 0.931 – 1.02 0.258 2123 19952 all phecode
681.5 Cellulitis and abscess of leg, except foot Dermatologic 0.98 0.937 – 1.02 0.358 2252 20944 all phecode
681.6 Cellulitis and abscess of foot, toe Dermatologic 0.994 0.947 – 1.04 0.815 1820 16893 all phecode
681.7 Cellulitis and abscess of trunk Dermatologic 1 0.95 – 1.06 0.956 1572 15588 all phecode
686
Other local infections of skin and subcutaneous
Other local infections of skin and subcutaneous tissue
 Dermatologic 1 0.958 – 1.05 0.944 2257 21750 all phecode
686.1 Carbuncle and furuncle Dermatologic 1.02 0.933 – 1.11 0.672 558 5504 all phecode
686.2 Impetigo Dermatologic 0.985 0.889 – 1.09 0.777 414 4117 all phecode
686.3 Pilonidal cyst Dermatologic 0.98 0.831 – 1.15 0.806 160 1594 all phecode
686.4 Pyogenic granuloma Dermatologic 0.857 0.727 – 1.01 0.0664 158 1570 all phecode
686.5 Pyoderma Dermatologic 1 0.777 – 1.29 0.982 63 630 all phecode
687 Symptoms affecting skin Dermatologic 0.984 0.936 – 1.03 0.532 1690 16343 all phecode
687.1 Rash and other nonspecific skin eruption Dermatologic 0.997 0.971 – 1.02 0.819 7007 34623 all phecode
687.3 Changes in skin texture Dermatologic 0.973 0.879 – 1.08 0.593 415 4121 all phecode
687.4 Disturbance of skin sensation Dermatologic 1.01 0.98 – 1.03 0.629 6375 34216 all phecode
689 Disorder of skin and subcutaneous tissue NOS Dermatologic 1.01 0.99 – 1.04 0.254 9311 37335 all phecode
690 Erythematosquamous dermatosis Dermatologic 1.02 0.991 – 1.05 0.165 5184 31581 all phecode
690.1 Seborrheic dermatitis Dermatologic 1.02 0.991 – 1.05 0.173 5174 31553 all phecode
691 Congenital anomalies of skin Dermatologic 0.901 0.825 – 0.985 0.0212 541 5337 all phecode
691.3 Congenital pigmentary anomalies of skin Dermatologic 0.962 0.745 – 1.24 0.768 62 613 all phecode
694 Dyschromia and Vitiligo Dermatologic 0.992 0.946 – 1.04 0.755 1861 17936 all phecode
694.1 Vitiligo Dermatologic 0.964 0.81 – 1.15 0.678 137 1347 all phecode
694.2 Other dyschromia Dermatologic 0.985 0.937 – 1.04 0.568 1674 16183 all phecode
694.3 Vascular disorders of skin Dermatologic 1.17 0.928 – 1.47 0.187 82 819 all phecode
695 Erythematous conditions Dermatologic 0.952 0.921 – 0.984 0.00351 4120 30247 all phecode
695.1 Toxic erythema Dermatologic 0.822 0.645 – 1.05 0.113 70 688 all phecode
695.2 Bullous dermatoses Dermatologic 0.953 0.758 – 1.2 0.684 85 805 all phecode
695.3 Rosacea Dermatologic 0.956 0.91 – 1 0.0712 1816 17663 all phecode
695.4 Lupus (localized and systemic) Dermatologic 0.935 0.863 – 1.01 0.105 672 6686 all phecode
695.41 Cutaneous lupus erythematosus Dermatologic 0.979 0.857 – 1.12 0.757 247 2437 all phecode
695.42 Systemic lupus erythematosus Dermatologic 0.934 0.86 – 1.02 0.109 637 6337 all phecode
695.7 Prurigo and Lichen Dermatologic 0.92 0.846 – 1 0.0538 605 5986 all phecode
695.8 Other specified erythematous conditions Dermatologic 0.884 0.822 – 0.95 0.000871 812 7980 all phecode
695.81 Erythema nodosum Dermatologic 0.944 0.724 – 1.23 0.672 55 550 all phecode
695.9 Unspecified erythematous condition Dermatologic 1.01 0.934 – 1.1 0.78 679 6756 all phecode
696 Psoriasis and related disorders Dermatologic 1.02 0.963 – 1.08 0.531 1401 13832 all phecode
696.3 Pityriasis Dermatologic 1.1 0.893 – 1.34 0.382 92 904 all phecode
696.4 Psoriasis Dermatologic 1.01 0.958 – 1.07 0.617 1311 12976 all phecode
696.41 Psoriasis vulgaris Dermatologic 1 0.942 – 1.06 0.997 1200 11867 all phecode
696.42 Psoriatic arthropathy Dermatologic 1.04 0.923 – 1.18 0.495 282 2810 all phecode
697 Sarcoidosis Dermatologic 0.965 0.862 – 1.08 0.536 333 3330 all phecode
698 Pruritus and related conditions Dermatologic 0.991 0.948 – 1.03 0.672 2254 21889 all phecode
700 Corns and callosities Dermatologic 0.968 0.913 – 1.03 0.27 1373 10894 all phecode
701
Other hypertrophic and atrophic conditions of
Other hypertrophic and atrophic conditions of skin
 Dermatologic 0.999 0.974 – 1.02 0.92 7651 38050 all phecode
701.1 Keratoderma, acquired Dermatologic 1.04 0.954 – 1.14 0.362 567 5524 all phecode
701.2 Scar conditions and fibrosis of skin Dermatologic 0.953 0.912 – 0.996 0.0332 2184 21550 all phecode
701.3 Circumscribed scleroderma Dermatologic 0.996 0.913 – 1.09 0.919 571 5660 all phecode
701.4 Keloid scar Dermatologic 0.946 0.867 – 1.03 0.213 578 5716 all phecode
701.5 Abnormal granulation tissue Dermatologic 0.954 0.861 – 1.06 0.374 400 3982 all phecode
702
Degenerative skin conditions and other
Degenerative skin conditions and other dermatoses
 Dermatologic 1.03 0.998 – 1.05 0.067 6956 29525 all phecode
702.1 Actinic keratosis Dermatologic 1.01 0.978 – 1.05 0.509 4171 26529 all phecode
702.2 Seborrheic keratosis Dermatologic 1.03 0.998 – 1.06 0.0719 5480 31552 all phecode
702.4 Degenerative skin disorders Dermatologic 1.08 0.871 – 1.34 0.481 86 832 all phecode
703 Diseases of nail, NOS Dermatologic 1 0.95 – 1.05 0.996 1650 14562 all phecode
703.1 Ingrowing nail Dermatologic 0.963 0.899 – 1.03 0.276 920 8597 all phecode
704 Diseases of hair and hair follicles Dermatologic 1 0.968 – 1.04 0.795 3118 29542 all phecode
704.1 Alopecia Dermatologic 1.03 0.974 – 1.09 0.31 1408 13871 all phecode
704.11 Alopecia Areata Dermatologic 1.11 0.884 – 1.39 0.373 82 811 all phecode
704.12 Telogen effluvium Dermatologic 1 0.774 – 1.29 0.998 63 615 all phecode
704.2 Hirsutism Dermatologic 1.04 0.926 – 1.18 0.483 299 2946 all phecode
704.8
Other specified diseases of hair and hair
Other specified diseases of hair and hair follicles
 Dermatologic 1 0.953 – 1.05 0.965 1752 17189 all phecode
705 Disorders of sweat glands Dermatologic 0.929 0.852 – 1.01 0.091 603 6012 all phecode
705.1 Dyshidrosis Dermatologic 0.855 0.725 – 1.01 0.0635 154 1540 all phecode
705.3 Hidradenitis Dermatologic 0.982 0.858 – 1.12 0.794 245 2440 all phecode
705.8 Hyperhidrosis Dermatologic 1.03 0.972 – 1.1 0.285 1112 10986 all phecode
706 Diseases of sebaceous glands Dermatologic 1.02 0.991 – 1.05 0.195 5995 39748 all phecode
706.1 Acne Dermatologic 1.02 0.979 – 1.06 0.341 2594 22570 all phecode
706.2 Sebaceous cyst Dermatologic 1.01 0.971 – 1.05 0.613 2814 26819 all phecode
706.3 Seborrhea Dermatologic 1.18 0.908 – 1.54 0.213 59 582 all phecode
706.8 Other specified diseases of sebaceous glands Dermatologic 1.02 0.965 – 1.07 0.547 1684 15289 all phecode
707 Chronic ulcer of skin Dermatologic 0.974 0.937 – 1.01 0.191 2871 26816 all phecode
707.1 Decubitus ulcer Dermatologic 1.02 0.952 – 1.1 0.536 825 8119 all phecode
707.2 Chronic ulcer of leg or foot Dermatologic 0.999 0.939 – 1.06 0.976 1108 9992 all phecode
707.3 Chronic ulcer of unspecified site Dermatologic 0.963 0.915 – 1.01 0.144 1641 16172 all phecode
709 Diffuse diseases of connective tissue Dermatologic 0.955 0.905 – 1.01 0.0973 1477 14427 all phecode
709.2 Sicca syndrome Dermatologic 0.984 0.898 – 1.08 0.739 505 4986 all phecode
709.3 Systemic sclerosis Dermatologic 0.883 0.766 – 1.02 0.0845 224 2209 all phecode
709.5 Dermatomyositis Dermatologic 0.917 0.736 – 1.14 0.442 92 892 all phecode
709.6
Other specified diffuse diseases of connective
Other specified diffuse diseases of connective tissue
 Dermatologic 0.889 0.716 – 1.1 0.285 90 892 all phecode
709.7 Unspecified diffuse connective tissue disease Dermatologic 0.923 0.862 – 0.988 0.0205 917 9089 all phecode
710
Osteomyelitis, periostitis, and other
Osteomyelitis, periostitis, and other infections involving bone
 Musculoskeletal 0.974 0.918 – 1.03 0.368 1254 12103 all phecode
710.1 Osteomyelitis Musculoskeletal 0.98 0.923 – 1.04 0.5 1203 11636 all phecode
710.11 Acute osteomyelitis Musculoskeletal 0.991 0.91 – 1.08 0.834 590 5708 all phecode
710.12 Chronic osteomyelitis Musculoskeletal 0.926 0.847 – 1.01 0.0925 531 5163 all phecode
710.19 Unspecified osteomyelitis Musculoskeletal 0.978 0.92 – 1.04 0.466 1153 11149 all phecode
711 Arthropathy associated with infections Musculoskeletal 0.877 0.793 – 0.97 0.0107 410 4099 all phecode
711.1 Pyogenic arthritis Musculoskeletal 0.933 0.827 – 1.05 0.262 290 2900 all phecode
712 Infective connective tissue disorders Musculoskeletal 0.901 0.773 – 1.05 0.183 178 1776 all phecode
713
Arthropathy associated with other disorders
Arthropathy associated with other disorders classified elsewhere
 Musculoskeletal 0.982 0.873 – 1.1 0.764 314 3028 all phecode
713.5
Arthropathy associated with neurological
Arthropathy associated with neurological disorders
 Musculoskeletal 1.03 0.885 – 1.19 0.728 194 1824 all phecode
714
Rheumatoid arthritis and other inflammatory
Rheumatoid arthritis and other inflammatory polyarthropathies
 Musculoskeletal 1 0.957 – 1.05 0.927 2086 18159 all phecode
714.1 Rheumatoid arthritis Musculoskeletal 0.985 0.936 – 1.04 0.57 1670 15087 all phecode
714.2 Juvenile rheumatoid arthritis Musculoskeletal 1.21 0.961 – 1.52 0.106 77 767 all phecode
715 Other inflammatory spondylopathies Musculoskeletal 0.98 0.923 – 1.04 0.507 1209 11967 all phecode
715.1 Sacroiliitis NEC Musculoskeletal 1.03 0.909 – 1.17 0.619 262 2611 all phecode
715.2 Ankylosing spondylitis Musculoskeletal 1.01 0.875 – 1.16 0.932 219 2182 all phecode
716 Other arthropathies Musculoskeletal 0.988 0.967 – 1.01 0.263 13482 31305 all phecode
716.1 Unspecified polyarthropathy or polyarthritis Musculoskeletal 0.993 0.856 – 1.15 0.928 192 1920 all phecode
716.2 Unspecified monoarthritis Musculoskeletal 1.04 0.871 – 1.24 0.677 131 1293 all phecode
716.9 Arthropathy NOS Musculoskeletal 0.988 0.967 – 1.01 0.251 13410 31294 all phecode
717 Polymyalgia Rheumatica Musculoskeletal 1.08 0.95 – 1.23 0.237 261 2565 all phecode
720 Spinal stenosis Musculoskeletal 1.01 0.976 – 1.04 0.591 3958 28539 all phecode
720.1 Spinal stenosis of lumbar region Musculoskeletal 1 0.966 – 1.04 0.839 2872 23656 all phecode
721 Spondylosis and allied disorders Musculoskeletal 0.989 0.961 – 1.02 0.465 5509 32391 all phecode
721.1 Spondylosis without myelopathy Musculoskeletal 0.99 0.961 – 1.02 0.514 5153 31896 all phecode
721.2 Spondylosis with myelopathy Musculoskeletal 0.991 0.924 – 1.06 0.81 867 8629 all phecode
721.8 Other allied disorders of spine Musculoskeletal 0.879 0.773 – 1 0.0499 262 2600 all phecode
722 Intervertebral disc disorders Musculoskeletal 1 0.977 – 1.03 0.765 6284 34317 all phecode
722.1 Displacement of intervertebral disc Musculoskeletal 1 0.969 – 1.04 0.848 3591 31411 all phecode
722.3 Schmorl's nodes Musculoskeletal 0.969 0.809 – 1.16 0.732 126 1248 all phecode
722.6 Degeneration of intervertebral disc Musculoskeletal 1 0.969 – 1.04 0.909 3957 30744 all phecode
722.7 Intervertebral disc disorder with myelopathy Musculoskeletal 1 0.917 – 1.1 0.921 515 5140 all phecode
722.8 Postlaminectomy syndrome Musculoskeletal 1.14 1.03 – 1.26 0.0145 397 3968 all phecode
722.9 Other and unspecified disc disorder Musculoskeletal 1.02 0.971 – 1.07 0.467 1932 19288 all phecode
723 Other disorders of cervical region Musculoskeletal 1.01 0.948 – 1.08 0.686 952 9495 all phecode
723.1 Torticollis Musculoskeletal 1.11 0.972 – 1.26 0.126 254 2522 all phecode
724 Other and unspecified disorders of back Musculoskeletal 1.01 0.982 – 1.05 0.377 4130 31954 all phecode
724.1 Disorders of sacrum Musculoskeletal 1.04 0.993 – 1.08 0.104 2307 21902 all phecode
724.2 Disorders of coccyx Musculoskeletal 1.03 0.932 – 1.14 0.565 426 4215 all phecode
724.8 Other symptoms referable to back Musculoskeletal 0.969 0.906 – 1.04 0.366 931 9295 all phecode
724.9 Other unspecified back disorders Musculoskeletal 1 0.951 – 1.06 0.863 1412 14087 all phecode
726 Peripheral enthesopathies and allied syndromes Musculoskeletal 0.988 0.965 – 1.01 0.29 9917 30176 all phecode
726.1 Enthesopathy Musculoskeletal 1 0.974 – 1.03 0.999 7507 30106 all phecode
726.2 Synoviopathy Musculoskeletal 0.944 0.885 – 1.01 0.0853 1015 9987 all phecode
726.3 Bursitis Musculoskeletal 0.98 0.933 – 1.03 0.427 1829 16722 all phecode
726.4 Calcaneal spur; Exostosis NOS Musculoskeletal 0.957 0.901 – 1.02 0.152 1193 11485 all phecode
727 Other disorders of synovium, tendon, and bursa Musculoskeletal 0.972 0.947 – 0.998 0.0329 7425 30105 all phecode
727.1 Synovitis and tenosynovitis Musculoskeletal 0.976 0.94 – 1.01 0.219 3092 24998 all phecode
727.2 Bursitis disorders Musculoskeletal 0.925 0.835 – 1.02 0.134 419 4112 all phecode
727.4 Ganglion and cyst of synovium, tendon, and bursa Musculoskeletal 0.993 0.939 – 1.05 0.797 1400 13621 all phecode
727.5 Rupture of synovium Musculoskeletal 1.02 0.93 – 1.13 0.633 480 4672 all phecode
727.6 Rupture of tendon, nontraumatic Musculoskeletal 0.975 0.934 – 1.02 0.234 2461 21948 all phecode
727.7 Contracture of tendon (sheath) Musculoskeletal 0.996 0.916 – 1.08 0.933 591 5893 all phecode
727.8 Plica syndrome Musculoskeletal 0.928 0.771 – 1.12 0.428 130 1264 all phecode
728 Disorders of muscle, ligament, and fascia Musculoskeletal 0.996 0.965 – 1.03 0.796 4546 29473 all phecode
728.1 Muscular calcification and ossification Musculoskeletal 1.15 0.919 – 1.44 0.221 85 843 all phecode
728.2 Laxity of ligament or hypermobility syndrome Musculoskeletal 0.997 0.885 – 1.12 0.957 297 2949 all phecode
728.7 Fasciitis Musculoskeletal 0.974 0.936 – 1.01 0.188 2814 23463 all phecode
728.71
Contracture of palmar fascia [Dupuytren's
Contracture of palmar fascia [Dupuytren's disease]
 Musculoskeletal 0.952 0.861 – 1.05 0.346 419 4138 all phecode
729 Other disorders of soft tissues Musculoskeletal 0.991 0.957 – 1.03 0.599 3642 27471 all phecode
729.1 Rheumatism, unspecified and fibrositis Musculoskeletal 0.941 0.744 – 1.19 0.611 74 726 all phecode
729.3 Panniculitis Musculoskeletal 0.947 0.781 – 1.15 0.582 119 1174 all phecode
729.7 Nontraumatic compartment syndrome Musculoskeletal 0.835 0.649 – 1.07 0.16 67 664 all phecode
731
Osteitis deformans and osteopathies associated
Osteitis deformans and osteopathies associated with other disorders classified elsewhere
 Musculoskeletal 0.863 0.744 – 1 0.0507 210 2091 all phecode
732 Osteochondropathies Musculoskeletal 0.969 0.871 – 1.08 0.557 361 3604 all phecode
732.1 Juvenile osteochondrosis Musculoskeletal 0.96 0.831 – 1.11 0.577 198 1969 all phecode
732.7 Osteochondritis dissecans Musculoskeletal 1.04 0.838 – 1.29 0.714 90 882 all phecode
733 Other disorders of bone and cartilage Musculoskeletal 1.01 0.981 – 1.05 0.416 4543 26941 all phecode
733.2 Cyst of bone Musculoskeletal 1.05 0.898 – 1.22 0.56 190 1900 all phecode
733.4 Aseptic necrosis of bone Musculoskeletal 0.992 0.907 – 1.09 0.869 518 5160 all phecode
733.6 Costochondritis Musculoskeletal 1 0.894 – 1.12 0.994 357 3562 all phecode
733.8 Malunion and nonunion of fracture Musculoskeletal 0.975 0.908 – 1.05 0.5 822 8205 all phecode
733.9 Chondromalacia Musculoskeletal 1.16 0.938 – 1.42 0.173 96 960 all phecode
735 Acquired foot deformities Musculoskeletal 0.984 0.949 – 1.02 0.381 3417 29622 all phecode
735.1 Flat foot Musculoskeletal 1.03 0.946 – 1.12 0.513 620 6092 all phecode
735.2 Acquired toe deformities Musculoskeletal 0.995 0.939 – 1.05 0.867 1323 11983 all phecode
735.21 Hammer toe (acquired) Musculoskeletal 0.969 0.901 – 1.04 0.4 825 7494 all phecode
735.23 Hallux rigidus Musculoskeletal 1.01 0.91 – 1.12 0.874 405 4005 all phecode
735.3 Hallux valgus (Bunion) Musculoskeletal 0.94 0.89 – 0.992 0.0242 1470 14295 all phecode
736 Other acquired deformities of limbs Musculoskeletal 0.972 0.934 – 1.01 0.161 2763 26555 all phecode
736.1 Acquired deformities of forearm Musculoskeletal 0.833 0.682 – 1.02 0.073 104 1033 all phecode
736.2 Acquired deformities of finger Musculoskeletal 1.08 0.937 – 1.24 0.297 215 2142 all phecode
736.3 Acquired deformities of hip Musculoskeletal 0.93 0.715 – 1.21 0.588 60 590 all phecode
736.4 Genu valgum or varum (acquired) Musculoskeletal 0.959 0.856 – 1.08 0.479 325 3247 all phecode
736.5 Acquired deformities of knee Musculoskeletal 0.995 0.871 – 1.14 0.942 246 2460 all phecode
736.6 Unequal leg length (acquired) Musculoskeletal 0.917 0.82 – 1.03 0.13 339 3365 all phecode
737 Curvature of spine Musculoskeletal 0.97 0.921 – 1.02 0.262 1566 15543 all phecode
737.1 Kyphosis (acquired) Musculoskeletal 1.03 0.936 – 1.13 0.574 479 4748 all phecode
737.2 Lordosis (acquired) Musculoskeletal 0.977 0.767 – 1.25 0.853 70 700 all phecode
737.3 Kyphoscoliosis and scoliosis Musculoskeletal 0.969 0.913 – 1.03 0.308 1203 11982 all phecode
738 Other acquired musculoskeletal deformity Musculoskeletal 0.971 0.931 – 1.01 0.168 2443 24187 all phecode
738.4 Acquired spondylolisthesis Musculoskeletal 0.96 0.901 – 1.02 0.211 1057 10542 all phecode
739 Contracture of joint Musculoskeletal 0.886 0.814 – 0.963 0.00466 621 6207 all phecode
740 Osteoarthrosis Musculoskeletal 0.992 0.972 – 1.01 0.423 16169 30268 all phecode
740.1 Osteoarthritis; localized Musculoskeletal 1 0.973 – 1.03 0.974 7005 27422 all phecode
740.11 Osteoarthrosis, localized, primary Musculoskeletal 0.997 0.969 – 1.03 0.847 6176 26155 all phecode
740.12 Osteoarthrosis, localized, secondary Musculoskeletal 0.979 0.905 – 1.06 0.59 713 7116 all phecode
740.2 Osteoarthrosis, generalized Musculoskeletal 1 0.952 – 1.06 0.9 1609 12092 all phecode
740.3
Osteoarthrosis involving more than one site
Osteoarthrosis involving more than one site, but not specified as generalized
 Musculoskeletal 0.942 0.846 – 1.05 0.273 373 3586 all phecode
740.9 Osteoarthrosis NOS Musculoskeletal 0.99 0.97 – 1.01 0.363 15497 30141 all phecode
741 Symptoms and disorders of the joints Musculoskeletal 0.996 0.972 – 1.02 0.732 8555 35884 all phecode
741.1 Ankylosis of joint Musculoskeletal 1.06 0.922 – 1.21 0.43 245 2445 all phecode
741.2 Stiffness of joint Musculoskeletal 1.02 0.961 – 1.08 0.537 1268 12594 all phecode
741.3 Difficulty in walking Musculoskeletal 1.02 0.977 – 1.06 0.383 2558 23116 all phecode
741.4 Joint effusions Musculoskeletal 1.01 0.968 – 1.05 0.677 2493 24199 all phecode
741.5 Hemarthrosis Musculoskeletal 1.17 0.951 – 1.44 0.138 94 937 all phecode
741.6 Villonodular synovitis Musculoskeletal 1.16 0.902 – 1.49 0.249 68 666 all phecode
742 Derangement of joint, non-traumatic Musculoskeletal 1.01 0.976 – 1.04 0.667 4404 33771 all phecode
742.1 Loose body in joint Musculoskeletal 1.2 1.02 – 1.42 0.0324 156 1554 all phecode
742.2
Pathological, developmental or recurrent
Pathological, developmental or recurrent dislocation
 Musculoskeletal 0.912 0.808 – 1.03 0.136 280 2792 all phecode
742.8 Articular cartilage disorder Musculoskeletal 1.05 0.924 – 1.2 0.444 245 2450 all phecode
742.9 Other derangement of joint Musculoskeletal 1.01 0.974 – 1.04 0.688 4107 32972 all phecode
743
Osteoporosis, osteopenia and pathological
Osteoporosis, osteopenia and pathological fracture
 Musculoskeletal 1 0.981 – 1.03 0.721 9223 36921 all phecode
743.1 Osteoporosis Musculoskeletal 0.998 0.962 – 1.04 0.931 3712 19477 all phecode
743.11 Osteoporosis NOS Musculoskeletal 0.997 0.96 – 1.03 0.854 3657 19276 all phecode
743.12 Senile osteoporosis Musculoskeletal 1.02 0.942 – 1.1 0.619 703 5804 all phecode
743.13 Other specified osteoporosis Musculoskeletal 1.03 0.916 – 1.15 0.638 321 3141 all phecode
743.2 Pathologic fracture Musculoskeletal 1.03 0.964 – 1.09 0.417 1112 10563 all phecode
743.21 Pathologic fracture of vertebrae Musculoskeletal 1.06 0.964 – 1.16 0.236 475 4629 all phecode
743.22 Pathologic fracture of femur Musculoskeletal 0.931 0.781 – 1.11 0.423 143 1391 all phecode
743.4 Stress fracture Musculoskeletal 1.05 0.948 – 1.16 0.35 407 4046 all phecode
743.9
Osteopenia or other disorder of bone and
Osteopenia or other disorder of bone and cartilage
 Musculoskeletal 1.01 0.98 – 1.03 0.622 6970 35237 all phecode
745 Pain in joint Musculoskeletal 0.992 0.974 – 1.01 0.386 19848 26918 all phecode
747 Cardiac and circulatory congenital anomalies Congenital Anomalies 0.985 0.942 – 1.03 0.492 2236 22256 all phecode
747.1 Cardiac congenital anomalies Congenital Anomalies 0.982 0.935 – 1.03 0.461 1767 17598 all phecode
747.11 Cardiac shunt/ heart septal defect Congenital Anomalies 0.926 0.854 – 1 0.0624 650 6497 all phecode
747.12 Valvular heart disease/ heart chambers Congenital Anomalies 1.01 0.936 – 1.09 0.812 751 7480 all phecode
747.13 Congenital anomalies of great vessels Congenital Anomalies 1.06 0.953 – 1.17 0.299 410 4090 all phecode
747.2
Congenital anomalies of peripheral vascular
Congenital anomalies of peripheral vascular system
 Congenital Anomalies 1.02 0.929 – 1.11 0.717 501 5010 all phecode
748 Anomalies of respiratory system, congenital Congenital Anomalies 0.914 0.746 – 1.12 0.39 111 1110 all phecode
749 Congenital anomalies of face and neck Congenital Anomalies 0.945 0.866 – 1.03 0.207 555 5549 all phecode
749.1 Cleft palate Congenital Anomalies 1.06 0.856 – 1.32 0.589 97 970 all phecode
749.2 Congenital anomalies of skull and face bones Congenital Anomalies 0.995 0.812 – 1.22 0.962 105 1041 all phecode
750 Digestive congenital anomalies Congenital Anomalies 1.02 0.949 – 1.09 0.629 893 8919 all phecode
750.1 Upper gastrointestinal congenital anomalies Congenital Anomalies 1.04 0.932 – 1.16 0.491 366 3655 all phecode
750.11 Esophageal atresia/tracheoesophageal fistula Congenital Anomalies 1.09 0.903 – 1.31 0.382 119 1185 all phecode
750.13 Congenital anomalies of mouth/tongue Congenital Anomalies 0.975 0.791 – 1.2 0.813 99 982 all phecode
750.14 Congenital anomalies of esophagus Congenital Anomalies 1.15 0.962 – 1.37 0.126 134 1332 all phecode
750.15 Congenital anomalies of stomach Congenital Anomalies 1.02 0.787 – 1.33 0.873 60 593 all phecode
750.2 Lower gastrointestinal congenital anomalies Congenital Anomalies 0.995 0.91 – 1.09 0.906 531 5300 all phecode
750.21 Congenital anomalies of intestine Congenital Anomalies 1.01 0.895 – 1.13 0.931 313 3129 all phecode
750.22
Congenital anomaly of gallbladder, bile ducts
Congenital anomaly of gallbladder, bile ducts, liver, pancreas
 Congenital Anomalies 0.977 0.851 – 1.12 0.744 222 2214 all phecode
751 Genitourinary congenital anomalies Congenital Anomalies 0.971 0.927 – 1.02 0.216 2008 19975 all phecode
751.1 Congenital anomalies of genital organs Congenital Anomalies 1.06 0.976 – 1.16 0.157 574 5740 all phecode
751.11 Congenital anomalies of female genital organs Congenital Anomalies 1.05 0.946 – 1.17 0.357 384 3840 all phecode
751.12 Congenital anomalies of male genital organs Congenital Anomalies 1.16 0.978 – 1.37 0.0889 153 1527 all phecode
751.2 Congenital anomalies of urinary system Congenital Anomalies 0.947 0.895 – 1 0.0544 1379 13704 all phecode
751.21 Cystic kidney disease Congenital Anomalies 0.927 0.868 – 0.991 0.0261 976 9685 all phecode
751.22 Other specified congenital anomalies of kidney Congenital Anomalies 0.975 0.865 – 1.1 0.676 294 2927 all phecode
751.3 Obstructive genitourinary defect Congenital Anomalies 0.997 0.855 – 1.16 0.965 182 1809 all phecode
752 Nervous system congenital anomalies Congenital Anomalies 0.975 0.917 – 1.04 0.428 1133 11313 all phecode
752.1 Neural tube defects Congenital Anomalies 0.97 0.906 – 1.04 0.391 923 9209 all phecode
752.11 Spina bifida Congenital Anomalies 1.16 0.989 – 1.35 0.0689 176 1760 all phecode
752.2
Other specified congenital anomalies of nervous
Other specified congenital anomalies of nervous system
 Congenital Anomalies 0.988 0.863 – 1.13 0.859 232 2320 all phecode
753 Congenital anomalies of the eye Congenital Anomalies 0.972 0.843 – 1.12 0.696 207 2051 all phecode
753.1 Congenital cataract and lens anomalies Congenital Anomalies 1.05 0.805 – 1.36 0.727 58 580 all phecode
753.2 Congenital anomalies of posterior segment of eye Congenital Anomalies 1.14 0.861 – 1.51 0.361 56 546 all phecode
754 Congenital musculoskeletal deformities of spine Congenital Anomalies 0.937 0.883 – 0.995 0.0339 1216 12116 all phecode
754.1 Lumbosacral spondylolysis, congenital Congenital Anomalies 1.1 0.915 – 1.32 0.314 135 1333 all phecode
754.2 Spondylolisthesis, congenital Congenital Anomalies 0.917 0.84 – 1 0.0549 558 5570 all phecode
755 Congenital anomalies of limbs Congenital Anomalies 0.986 0.914 – 1.06 0.724 747 7458 all phecode
755.1 Congenital deformities of feet Congenital Anomalies 0.983 0.883 – 1.09 0.76 368 3663 all phecode
755.4
Congenital anomalies of upper limb, including
Congenital anomalies of upper limb, including shoulder girdle
 Congenital Anomalies 1.05 0.822 – 1.34 0.694 74 740 all phecode
755.6
Other congenital anomalies of lower limb
Other congenital anomalies of lower limb, including pelvic girdle
 Congenital Anomalies 0.953 0.849 – 1.07 0.412 321 3205 all phecode
755.61 Congenital hip dysplasia and deformity Congenital Anomalies 1.01 0.871 – 1.18 0.878 185 1847 all phecode
756 Other congenital musculoskeletal anomalies Congenital Anomalies 0.968 0.915 – 1.02 0.258 1358 13579 all phecode
756.1 Congenital anomalies of abdominal wall; diaphram Congenital Anomalies 1.06 0.83 – 1.36 0.625 68 680 all phecode
756.2
Pectus and other congenital anomalies of
Pectus and other congenital anomalies of ribs/sternum
 Congenital Anomalies 1.05 0.821 – 1.34 0.71 71 694 all phecode
756.3
Congenital anomalies of muscle, tendon, fascia
Congenital anomalies of muscle, tendon, fascia, and connective tissue
 Congenital Anomalies 1.01 0.905 – 1.13 0.837 335 3346 all phecode
756.5 Congenital osteodystrophies Congenital Anomalies 0.99 0.927 – 1.06 0.754 1003 10014 all phecode
757 Congenital anomalies of the integument Congenital Anomalies 0.975 0.88 – 1.08 0.632 401 4001 all phecode
758 Chromosomal anomalies and genetic disorders Congenital Anomalies 0.956 0.823 – 1.11 0.562 185 1845 all phecode
758.1 Chromosomal anomalies Congenital Anomalies 0.967 0.81 – 1.15 0.711 135 1349 all phecode
759 Other and unspecified congenital anomalies Congenital Anomalies 0.944 0.865 – 1.03 0.195 557 5566 all phecode
759.1 Anomalies of endocrine glands, congenital Congenital Anomalies 0.826 0.646 – 1.06 0.126 71 710 all phecode
760 Back pain Symptoms 1 0.985 – 1.02 0.646 16037 30719 all phecode
761 Cervicalgia Symptoms 1 0.976 – 1.03 0.874 6528 39755 all phecode
763
Thoracic or lumbosacral neuritis or
Thoracic or lumbosacral neuritis or radiculitis, unspecified
 Symptoms 1 0.969 – 1.04 0.856 3657 32599 all phecode
764 Sciatica Symptoms 1.02 0.982 – 1.05 0.34 3542 32015 all phecode
765 Cervical radiculitis Symptoms 1.03 0.982 – 1.08 0.224 1799 17851 all phecode
766 Neuralgia, neuritis, and radiculitis NOS Symptoms 1.01 0.976 – 1.04 0.706 5124 37132 all phecode
767 Cervicocranial/Cervicobrachial syndrome Symptoms 1.02 0.845 – 1.24 0.812 117 1168 all phecode
769 Nonallopathic lesions NEC Symptoms 1.03 0.972 – 1.1 0.284 1131 11220 all phecode
770 Myalgia and myositis unspecified Symptoms 1.02 0.989 – 1.05 0.238 5533 34303 all phecode
771 Musculoskeletal symptoms referable to limbs Symptoms 0.969 0.94 – 0.999 0.046 4799 35575 all phecode
771.1 Swelling of limb Symptoms 0.969 0.942 – 0.997 0.0313 5743 35539 all phecode
771.2 Cramp of limb Symptoms 1.02 0.955 – 1.08 0.583 1079 10568 all phecode
772 Symptoms of the muscles Symptoms 0.976 0.932 – 1.02 0.304 2042 20221 all phecode
772.1 Muscular wasting and disuse atrophy Symptoms 0.96 0.869 – 1.06 0.428 422 4199 all phecode
772.2 Spasm of muscle Symptoms 0.987 0.945 – 1.03 0.556 2299 22726 all phecode
772.3 Muscle weakness Symptoms 1.01 0.97 – 1.05 0.688 2949 28064 all phecode
772.4 Rhabdomyolysis Symptoms 1.13 0.956 – 1.34 0.152 159 1572 all phecode
772.6 Facial weakness Symptoms 0.973 0.884 – 1.07 0.583 478 4742 all phecode
780 Hypothermia/Chills Symptoms 0.983 0.892 – 1.08 0.734 453 4514 all phecode
781
Symptoms involving nervous and musculoskeletal
Symptoms involving nervous and musculoskeletal systems
 Symptoms 0.973 0.936 – 1.01 0.169 2822 26225 all phecode
781.1 Loss of height Symptoms 0.968 0.812 – 1.16 0.72 130 1269 all phecode
781.2 Abnormal posture Symptoms 0.804 0.619 – 1.04 0.102 57 567 all phecode
782.3 Edema Symptoms 0.976 0.949 – 1 0.094 5874 36788 all phecode
782.6 Pallor and flushing Symptoms 1.04 0.975 – 1.12 0.223 927 9252 all phecode
783 Fever of unknown origin Symptoms 1.01 0.978 – 1.03 0.714 5733 40720 all phecode
783.1 Postprocedural fever Symptoms 0.895 0.795 – 1.01 0.069 300 2992 all phecode
785 Abdominal pain Symptoms 1 0.983 – 1.02 0.828 16458 30297 all phecode
788 Syncope and collapse Symptoms 1.01 0.975 – 1.04 0.626 3851 35832 all phecode
789 Nausea and vomiting Symptoms 1.02 0.997 – 1.04 0.0987 10568 36098 all phecode
789.1 Persistent vomiting Symptoms 0.985 0.916 – 1.06 0.688 798 7924 all phecode
790 Nonspecific findings on examination of blood Symptoms 0.998 0.956 – 1.04 0.922 2363 22690 all phecode
790.1 Elevated sedimentation rate Symptoms 1.11 0.973 – 1.27 0.12 236 2322 all phecode
790.6 Other abnormal blood chemistry Symptoms 1.02 0.998 – 1.05 0.0738 7539 37788 all phecode
790.8 Elevated C-reactive protein (CRP) Symptoms 1.04 0.93 – 1.17 0.465 309 3075 all phecode
790.9 Abnormal arterial blood gases Symptoms 0.908 0.767 – 1.07 0.262 155 1521 all phecode
791 Gangrene Symptoms 0.974 0.865 – 1.1 0.665 313 3115 all phecode
792
Abnormal Papanicolaou smear of cervix and
Abnormal Papanicolaou smear of cervix and cervical HPV
 Genitourinary 0.987 0.947 – 1.03 0.523 2820 14872 all phecode
792.1
Papanicolaou smear of cervix or vagina with
Papanicolaou smear of cervix or vagina with atypical squamous cells
 Genitourinary 0.999 0.938 – 1.06 0.972 1100 9861 all phecode
794
Abnormal results of other function studies
Abnormal results of other function studies (bladder, pancreas, placenta, spleen, etc)
 Symptoms 1.03 0.938 – 1.13 0.545 515 5133 all phecode
795
Other and nonspecific abnormal cytological
Other and nonspecific abnormal cytological, histological and immunological findings
 Symptoms 0.984 0.941 – 1.03 0.48 2182 20242 all phecode
795.8 Abnormal tumor markers Symptoms 0.991 0.942 – 1.04 0.712 1745 15551 all phecode
795.81 Elevated carcinoembryonic antigen [CEA] Symptoms 0.98 0.756 – 1.27 0.877 61 605 all phecode
795.82 Elevated cancer antigen 125 [CA 125] Symptoms 0.985 0.851 – 1.14 0.845 201 2000 all phecode
796 Elevated prostate specific antigen [PSA] Genitourinary 1.01 0.963 – 1.06 0.689 2125 9930 all phecode
797 Shock Symptoms 1.04 0.952 – 1.13 0.417 605 6050 all phecode
797.1 Cardiogenic shock Symptoms 1.05 0.918 – 1.21 0.457 242 2420 all phecode
798 Malaise and fatigue Symptoms 1.03 1.01 – 1.05 0.0128 11539 35196 all phecode
798.1 Chronic fatigue syndrome Symptoms 1.03 0.978 – 1.08 0.283 1823 17795 all phecode
800 Fracture of lower limb Injuries & Poisonings 0.998 0.956 – 1.04 0.923 2344 22951 all phecode
800.1 Fracture of neck of femur Injuries & Poisonings 0.983 0.896 – 1.08 0.709 512 4961 all phecode
800.2 Fracture of unspecified part of femur Injuries & Poisonings 0.998 0.922 – 1.08 0.965 670 6582 all phecode
800.3 Fracture of tibia and fibula Injuries & Poisonings 1 0.934 – 1.07 0.968 898 8966 all phecode
800.4 Fracture of patella Injuries & Poisonings 0.965 0.864 – 1.08 0.523 346 3456 all phecode
801 Fracture of ankle and foot Injuries & Poisonings 0.998 0.956 – 1.04 0.925 2358 22645 all phecode
801.1 Fracture of foot Injuries & Poisonings 1.03 0.964 – 1.09 0.423 1120 11178 all phecode
802 Fracture of pelvis Injuries & Poisonings 1.13 1.01 – 1.26 0.028 380 3765 all phecode
803 Fracture of upper limb Injuries & Poisonings 0.983 0.939 – 1.03 0.476 2051 20360 all phecode
803.1 Fracture of humerus Injuries & Poisonings 1 0.928 – 1.08 0.952 734 7322 all phecode
803.2 Fracture of radius and ulna Injuries & Poisonings 0.964 0.906 – 1.03 0.251 1112 11075 all phecode
803.21 Colles' fracture Injuries & Poisonings 0.969 0.859 – 1.09 0.611 291 2904 all phecode
803.3 Fracture of clavicle or scapula Injuries & Poisonings 0.975 0.89 – 1.07 0.583 514 5140 all phecode
804 Fracture of hand or wrist Injuries & Poisonings 0.974 0.925 – 1.03 0.323 1628 16042 all phecode
805
Fracture of vertebral column without mention of
Fracture of vertebral column without mention of spinal cord injury
 Injuries & Poisonings 1.03 0.973 – 1.09 0.318 1336 13242 all phecode
807 Fracture of ribs Injuries & Poisonings 1 0.925 – 1.08 0.971 683 6815 all phecode
809 Fracture of unspecified bones Injuries & Poisonings 1 0.963 – 1.04 0.952 2941 28633 all phecode
816 Cerebral laceration and contusion Injuries & Poisonings 0.749 0.567 – 0.991 0.0428 54 531 all phecode
817 Concussion Injuries & Poisonings 1.01 0.946 – 1.08 0.771 1018 10149 all phecode
818 Intracranial hemorrhage (injury) Injuries & Poisonings 0.936 0.832 – 1.05 0.269 311 3104 all phecode
818.1 Subdural hemorrhage (injury) Injuries & Poisonings 0.937 0.761 – 1.15 0.544 90 895 all phecode
818.2 Subarachnoid hemorrhage (injury) Injuries & Poisonings 1.05 0.853 – 1.29 0.644 97 970 all phecode
819
Skull and face fracture and other intercranial
Skull and face fracture and other intercranial injury
 Injuries & Poisonings 0.998 0.956 – 1.04 0.945 2287 22671 all phecode
830 Dislocation Injuries & Poisonings 1.02 0.984 – 1.05 0.304 3862 34720 all phecode
835 Internal derangement of knee Injuries & Poisonings 1.01 0.966 – 1.06 0.661 2231 21628 all phecode
836 Traumatic arthropathy Injuries & Poisonings 0.954 0.869 – 1.05 0.324 496 4954 all phecode
840 Sprains and strains Injuries & Poisonings 0.989 0.965 – 1.01 0.37 7838 37998 all phecode
840.1 Muscle/tendon sprain Injuries & Poisonings 0.964 0.882 – 1.05 0.419 537 5356 all phecode
840.2 Rotator cuff (capsule) sprain Injuries & Poisonings 0.985 0.936 – 1.04 0.559 1640 16263 all phecode
840.3 Joint/ligament sprain Injuries & Poisonings 0.976 0.939 – 1.02 0.231 2875 24879 all phecode
841 Sprains and strains of back and neck Injuries & Poisonings 0.943 0.895 – 0.993 0.0262 1583 15592 all phecode
842 Other sprains and strains Injuries & Poisonings 1 0.95 – 1.06 0.877 1407 13924 all phecode
850 Hemorrhage or hematoma complicating a procedure Injuries & Poisonings 0.959 0.917 – 1 0.0745 2072 20649 all phecode
851
Complications of transplants and reattached
Complications of transplants and reattached limbs
 Injuries & Poisonings 0.977 0.94 – 1.01 0.223 2982 27545 all phecode
853 Complication of colostomy or enterostomy Injuries & Poisonings 1.05 0.954 – 1.16 0.305 460 4600 all phecode
854
Complications of cardiac/vascular device
Complications of cardiac/vascular device, implant, and graft
 Injuries & Poisonings 1.03 0.983 – 1.08 0.214 1985 19675 all phecode
855
Complication of nervous system device, implant
Complication of nervous system device, implant, and graft
 Injuries & Poisonings 1.03 0.903 – 1.17 0.696 264 2640 all phecode
856
Vascular complications of surgery and medical
Vascular complications of surgery and medical procedures
 Injuries & Poisonings 1.04 0.921 – 1.17 0.526 293 2929 all phecode
857
Mechanical complication of unspecified
Mechanical complication of unspecified genitourinary device, implant, and graft
 Injuries & Poisonings 0.944 0.891 – 0.999 0.0469 1310 13087 all phecode
858 Complication of internal orthopedic device Injuries & Poisonings 0.996 0.953 – 1.04 0.859 2213 21944 all phecode
859
Complication due to other implant and internal
Complication due to other implant and internal device
 Injuries & Poisonings 0.985 0.942 – 1.03 0.517 2110 21070 all phecode
860 Bone marrow or stem cell transplant Neoplasms 0.995 0.848 – 1.17 0.947 166 1660 all phecode
870 Open wounds of head; neck; and trunk Injuries & Poisonings 0.993 0.961 – 1.03 0.676 4117 36734 all phecode
870.1 Open wound or laceration of eye or eyelid Injuries & Poisonings 1.03 0.89 – 1.18 0.721 204 2026 all phecode
870.2 Open wound of ear Injuries & Poisonings 0.96 0.807 – 1.14 0.642 144 1437 all phecode
870.3 Other open wound of head and face Injuries & Poisonings 0.943 0.891 – 0.999 0.0443 1346 13301 all phecode
870.4 Open wound of nose and sinus Injuries & Poisonings 0.956 0.827 – 1.1 0.537 207 2057 all phecode
870.5 Open wound of lip and mouth Injuries & Poisonings 1.02 0.896 – 1.15 0.802 275 2724 all phecode
870.6 Open wound of neck Injuries & Poisonings 0.985 0.856 – 1.13 0.83 214 2128 all phecode
870.8 Open wound of genital organs Injuries & Poisonings 1.18 0.998 – 1.4 0.0529 144 1440 all phecode
871 Open wounds of extremities Injuries & Poisonings 0.99 0.956 – 1.03 0.576 3530 32903 all phecode
871.1 Open wound of hand except finger(s) Injuries & Poisonings 0.971 0.89 – 1.06 0.52 572 5701 all phecode
871.2 Open wound of finger(s) Injuries & Poisonings 1.03 0.964 – 1.1 0.385 984 9772 all phecode
871.3 Open wound of foot except toe(s) alone Injuries & Poisonings 0.988 0.9 – 1.09 0.808 490 4843 all phecode
871.4 Open wound of toe(s) Injuries & Poisonings 1 0.89 – 1.13 0.962 295 2921 all phecode
872 Traumatic amputation Injuries & Poisonings 1 0.916 – 1.09 0.98 551 5477 all phecode
874 Complication of amputation stump Injuries & Poisonings 0.895 0.761 – 1.05 0.181 170 1697 all phecode
875 Non-healing surgical wound Injuries & Poisonings 0.955 0.874 – 1.04 0.304 572 5720 all phecode
876
Posttraumatic wound infection not elsewhere
Posttraumatic wound infection not elsewhere classified
 Injuries & Poisonings 1.03 0.956 – 1.11 0.437 802 8003 all phecode
907 Injuries to the nervous system Injuries & Poisonings 1.08 1.01 – 1.15 0.0246 1010 10096 all phecode
910 Superficial injury, infected Injuries & Poisonings 1 0.828 – 1.21 0.993 119 1161 all phecode
911 Blister Injuries & Poisonings 0.906 0.802 – 1.02 0.113 302 2996 all phecode
912 Insect bite Injuries & Poisonings 0.958 0.873 – 1.05 0.373 492 4886 all phecode
913 Toxic effect of venom Injuries & Poisonings 0.993 0.888 – 1.11 0.908 337 3326 all phecode
916 Contusion Injuries & Poisonings 0.997 0.965 – 1.03 0.836 4296 38033 all phecode
930 Allergic reaction to food Injuries & Poisonings 0.922 0.856 – 0.994 0.0335 763 7596 all phecode
931
Contact dermatitis and other eczema due to
Contact dermatitis and other eczema due to plants [except food]
 Dermatologic 0.969 0.897 – 1.05 0.421 714 7072 all phecode
938 Dermatitis due to solar radiation Dermatologic 1.02 0.993 – 1.05 0.135 5567 29098 all phecode
938.1 Acute dermatitis due to solar radiation Dermatologic 0.995 0.868 – 1.14 0.945 217 2164 all phecode
938.2 Chronic dermatitis due to solar radiation Dermatologic 1.02 0.991 – 1.05 0.163 5307 28656 all phecode
939
Atopic/contact dermatitis due to other or
Atopic/contact dermatitis due to other or unspecified
 Dermatologic 1 0.977 – 1.03 0.776 6704 32389 all phecode
939.1 Contact and allergic dermatitis of eyelid Dermatologic 0.975 0.787 – 1.21 0.815 91 870 all phecode
941 Adverse reaction to serum or vaccine Injuries & Poisonings 1.1 0.946 – 1.29 0.211 188 1880 all phecode
942 Infusion and transfusion reaction Injuries & Poisonings 1.01 0.891 – 1.15 0.863 269 2688 all phecode
946 Anaphylactic shock NOS Injuries & Poisonings 0.993 0.904 – 1.09 0.88 500 4940 all phecode
947 Urticaria Dermatologic 0.979 0.921 – 1.04 0.487 1177 11454 all phecode
949 Allergies, other Injuries & Poisonings 1.01 0.983 – 1.04 0.502 7251 32350 all phecode
952
Spinal cord injury without evidence of spinal
Spinal cord injury without evidence of spinal bone injury
 Injuries & Poisonings 1.06 0.968 – 1.17 0.199 494 4940 all phecode
957 Injury to other and unspecified nerves Injuries & Poisonings 0.99 0.83 – 1.18 0.907 136 1352 all phecode
958
Certain early complications of trauma or
Certain early complications of trauma or procedure
 Injuries & Poisonings 0.979 0.922 – 1.04 0.483 1217 12158 all phecode
958.1 Postoperative shock Injuries & Poisonings 1.12 0.952 – 1.31 0.172 169 1688 all phecode
958.2 Traumatic and surgical subcutaneous emphysema Injuries & Poisonings 1.08 0.897 – 1.31 0.402 114 1140 all phecode
960 Poisoning by antibiotics Injuries & Poisonings 0.962 0.922 – 1 0.0689 2479 22087 all phecode
960.1
Adverse effects of antibacterials (not
Adverse effects of antibacterials (not penicillins)
 Injuries & Poisonings 0.992 0.888 – 1.11 0.887 342 3403 all phecode
960.2 Allergy/adverse effect of penicillin Injuries & Poisonings 0.972 0.923 – 1.02 0.282 1636 16005 all phecode
961 Poisoning by other anti-infectives Injuries & Poisonings 1.05 0.96 – 1.15 0.274 528 5234 all phecode
961.1 Poisoning/allergy of sulfonamides Injuries & Poisonings 0.972 0.912 – 1.04 0.387 1065 10347 all phecode
962 Poisoning by hormones and synthetic substitutes Injuries & Poisonings 0.984 0.914 – 1.06 0.673 803 7976 all phecode
962.1
Adrenal cortical steroids causing adverse
Adrenal cortical steroids causing adverse effects in therapeutic use
 Injuries & Poisonings 0.945 0.849 – 1.05 0.306 379 3782 all phecode
962.2
Insulins and antidiabetic agents causing
Insulins and antidiabetic agents causing adverse effects in therapeutic use
 Injuries & Poisonings 0.836 0.644 – 1.08 0.176 62 612 all phecode
962.3
Hormones and synthetic substitutes causing
Hormones and synthetic substitutes causing adverse effects in therapeutic use
 Injuries & Poisonings 1.05 0.956 – 1.16 0.302 478 4773 all phecode
963 Poisoning by primarily systemic agents Injuries & Poisonings 1.01 0.971 – 1.06 0.556 2533 24531 all phecode
963.1
Antineoplastic and immunosuppressive drugs
Antineoplastic and immunosuppressive drugs causing adverse effects
 Injuries & Poisonings 1.02 0.979 – 1.06 0.336 2469 24057 all phecode
964
Poisoning by agents primarily affecting blood
Poisoning by agents primarily affecting blood constituents
 Injuries & Poisonings 1.03 0.955 – 1.11 0.439 743 7337 all phecode
964.1 Anticoagulants causing adverse effects Injuries & Poisonings 1.03 0.949 – 1.11 0.518 712 7027 all phecode
965
Poisoning by analgesics, antipyretics, and
Poisoning by analgesics, antipyretics, and antirheumatics
 Injuries & Poisonings 1.05 0.978 – 1.13 0.175 864 8601 all phecode
965.1
Opiates and related narcotics causing adverse
Opiates and related narcotics causing adverse effects in therapeutic use
 Injuries & Poisonings 1.04 0.985 – 1.1 0.161 1469 14402 all phecode
965.3
Salicylates causing adverse effects in
Salicylates causing adverse effects in therapeutic use
 Injuries & Poisonings 1.05 0.87 – 1.26 0.634 119 1182 all phecode
966
Poisoning by anticonvulsants and
Poisoning by anticonvulsants and anti-Parkinsonism drugs
 Injuries & Poisonings 1.01 0.822 – 1.23 0.952 103 1006 all phecode
967
Adverse effects of sedatives or other central
Adverse effects of sedatives or other central nervous system depressants and anesthetics
 Injuries & Poisonings 0.976 0.921 – 1.04 0.421 1254 12464 all phecode
969 Poisoning by psychotropic agents Injuries & Poisonings 1.08 0.955 – 1.22 0.224 281 2797 all phecode
971
Poisoning by drugs primarily affecting the
Poisoning by drugs primarily affecting the autonomic nervous system
 Injuries & Poisonings 0.858 0.667 – 1.1 0.234 67 643 all phecode
972
Poisoning by agents primarily affecting the
Poisoning by agents primarily affecting the cardiovascular system
 Injuries & Poisonings 1.02 0.901 – 1.14 0.806 288 2858 all phecode
972.1
Cardiac rhythm regulators causing adverse
Cardiac rhythm regulators causing adverse effects in therapeutic use
 Injuries & Poisonings 1.06 0.84 – 1.34 0.616 80 776 all phecode
972.6 Antihypertensive agents causing adverse effects Injuries & Poisonings 0.868 0.712 – 1.06 0.161 104 1034 all phecode
974
Poisoning by water, mineral, and uric acid
Poisoning by water, mineral, and uric acid metabolism drugs
 Injuries & Poisonings 1.07 0.883 – 1.31 0.474 113 1130 all phecode
975
Poisoning by agents primarily acting on the
Poisoning by agents primarily acting on the smooth and skeletal muscles and respiratory system
 Injuries & Poisonings 0.9 0.718 – 1.13 0.362 81 810 all phecode
976
Poisoning by agents primarily affecting skin &
Poisoning by agents primarily affecting skin & mucous membrane, ophthalmological, otorhinolaryngological, & dental drugs
 Injuries & Poisonings 1.27 0.991 – 1.62 0.0585 71 703 all phecode
977 Personal history of allergy to medicinal agents Injuries & Poisonings 0.978 0.93 – 1.03 0.373 1763 16599 all phecode
979 Adverse drug events and drug allergies Injuries & Poisonings 1.03 0.998 – 1.07 0.0626 3448 30885 all phecode
980
Encounter for long-term (current) use of
Encounter for long-term (current) use of antibiotics
 Infectious Diseases 0.95 0.899 – 1 0.0671 1391 13877 all phecode
985 Toxic effect of other metals Injuries & Poisonings 1.39 1.05 – 1.86 0.0224 57 564 all phecode
989
Toxic effect of other substances, chiefly
Toxic effect of other substances, chiefly nonmedicinal as to source
 Injuries & Poisonings 0.93 0.774 – 1.12 0.444 129 1275 all phecode
990 Effects radiation NOS Injuries & Poisonings 1.01 0.974 – 1.04 0.667 3927 31223 all phecode
994 Sepsis and SIRS Injuries & Poisonings 0.988 0.945 – 1.03 0.581 2192 21710 all phecode
994.1 Systemic inflammatory response syndrome (SIRS) Injuries & Poisonings 0.998 0.883 – 1.13 0.975 291 2910 all phecode
994.2 Sepsis Injuries & Poisonings 0.986 0.942 – 1.03 0.538 2086 20666 all phecode
994.21 Septic shock Injuries & Poisonings 0.975 0.899 – 1.06 0.552 627 6260 all phecode
008 Intestinal infection Infectious Diseases 1 0.942 – 1.07 0.919 1214 5969 exclusion phecode
008.5 Bacterial enteritis Infectious Diseases 1.07 0.968 – 1.17 0.191 510 2623 exclusion phecode
008.52 Intestinal infection due to C. difficile Infectious Diseases 1.09 0.979 – 1.22 0.114 397 2047 exclusion phecode
008.6 Viral Enteritis Infectious Diseases 1 0.887 – 1.13 1 359 1633 exclusion phecode
010 Tuberculosis Infectious Diseases 0.992 0.783 – 1.26 0.948 80 466 exclusion phecode
031 Diseases due to other mycobacteria Infectious Diseases 0.925 0.662 – 1.29 0.649 40 184 exclusion phecode
038 Septicemia Infectious Diseases 1.09 1.02 – 1.16 0.0164 1053 4659 exclusion phecode
038.1 Gram negative septicemia Infectious Diseases 1.04 0.909 – 1.18 0.585 276 1157 exclusion phecode
038.2 Gram positive septicemia Infectious Diseases 0.978 0.776 – 1.23 0.852 106 482 exclusion phecode
038.3 Bacteremia Infectious Diseases 1.09 0.993 – 1.19 0.0696 573 2429 exclusion phecode
041 Bacterial infection NOS Infectious Diseases 1.04 0.988 – 1.09 0.134 2016 7043 exclusion phecode
041.1 Staphylococcus infections Infectious Diseases 1.05 0.963 – 1.15 0.26 588 3190 exclusion phecode
041.11 Methicillin sensitive Staphylococcus aureus Infectious Diseases 1.05 0.935 – 1.18 0.409 362 1830 exclusion phecode
041.12 Methicillin resistant Staphylococcus aureus Infectious Diseases 1.02 0.891 – 1.17 0.767 256 1459 exclusion phecode
041.2 Streptococcus infection Infectious Diseases 1 0.923 – 1.09 0.913 660 3108 exclusion phecode
041.21 Rheumatic fever / chorea Infectious Diseases 1.07 0.845 – 1.36 0.561 77 495 exclusion phecode
041.4 E. coli Infectious Diseases 1.05 0.953 – 1.17 0.309 481 2254 exclusion phecode
041.8 H. pylori Infectious Diseases 0.937 0.736 – 1.19 0.598 84 501 exclusion phecode
041.9 Infection with drug-resistant microorganisms Infectious Diseases 1.09 0.912 – 1.29 0.355 167 713 exclusion phecode
053 Herpes zoster Infectious Diseases 0.973 0.892 – 1.06 0.543 635 2754 exclusion phecode
053.1 Herpes zoster with nervous system complications Infectious Diseases 0.843 0.659 – 1.08 0.173 89 383 exclusion phecode
054 Herpes simplex Infectious Diseases 1.01 0.914 – 1.1 0.916 542 2601 exclusion phecode
070 Viral hepatitis Infectious Diseases 0.936 0.819 – 1.07 0.328 269 1416 exclusion phecode
070.1 Viral hepatitis A Infectious Diseases 0.745 0.481 – 1.16 0.189 22 157 exclusion phecode
070.2 Viral hepatitis B Infectious Diseases 0.992 0.763 – 1.29 0.952 69 338 exclusion phecode
070.3 Viral hepatitis C Infectious Diseases 0.92 0.782 – 1.08 0.311 179 886 exclusion phecode
070.4 Chronic hepatitis Infectious Diseases 1.01 0.796 – 1.29 0.916 87 339 exclusion phecode
070.9 Hepatitis NOS Infectious Diseases 0.93 0.829 – 1.04 0.211 355 1924 exclusion phecode
071 Human immunodeficiency virus [HIV] disease Infectious Diseases 1.05 0.801 – 1.37 0.735 58 266 exclusion phecode
071.1 HIV infection, symptomatic Infectious Diseases 1.23 0.891 – 1.69 0.211 48 209 exclusion phecode
078 Viral warts & HPV Infectious Diseases 0.996 0.936 – 1.06 0.9 1270 4660 exclusion phecode
079 Viral infection Infectious Diseases 1 0.957 – 1.05 0.882 2623 5564 exclusion phecode
079.1 Varicella infection Infectious Diseases 0.987 0.93 – 1.05 0.665 1417 5081 exclusion phecode
079.2 Infectious mononucleosis Infectious Diseases 1.04 0.814 – 1.33 0.742 83 420 exclusion phecode
079.9 Viremia, NOS Infectious Diseases 1.12 0.999 – 1.25 0.0528 402 1449 exclusion phecode
080 Postoperative infection Infectious Diseases 1.03 0.949 – 1.11 0.521 735 4968 exclusion phecode
081
Infection/inflammation of internal prosthetic
Infection/inflammation of internal prosthetic device; implant; and graft
 Infectious Diseases 1.07 0.974 – 1.18 0.159 508 3016 exclusion phecode
090
Sexually transmitted infections (not HIV or
Sexually transmitted infections (not HIV or hepatitis)
 Infectious Diseases 1.06 0.952 – 1.19 0.278 364 2162 exclusion phecode
110 Dermatophytosis / Dermatomycosis Infectious Diseases 0.998 0.945 – 1.06 0.953 1708 5487 exclusion phecode
110.1 Dermatophytosis Infectious Diseases 0.991 0.936 – 1.05 0.752 1602 5067 exclusion phecode
110.11 Dermatophytosis of nail Infectious Diseases 1.03 0.964 – 1.1 0.37 1103 3455 exclusion phecode
110.12 Althete's foot Infectious Diseases 1.02 0.926 – 1.13 0.637 468 1839 exclusion phecode
110.13 Dermatophytosis of the body Infectious Diseases 0.958 0.848 – 1.08 0.486 340 1572 exclusion phecode
110.2 Dermatomycoses Infectious Diseases 1.03 0.865 – 1.22 0.767 153 785 exclusion phecode
112 Candidiasis Infectious Diseases 1.06 0.998 – 1.13 0.0586 1296 5197 exclusion phecode
112.3 Candidiasis of skin and nails Infectious Diseases 0.946 0.828 – 1.08 0.417 269 1195 exclusion phecode
117 Mycoses Infectious Diseases 1.03 0.889 – 1.2 0.668 212 1115 exclusion phecode
117.1 Histoplasmosis Infectious Diseases 0.918 0.573 – 1.47 0.722 20 160 exclusion phecode
117.4 Aspergillosis Infectious Diseases 1.32 0.971 – 1.8 0.0759 55 271 exclusion phecode
130 Spirochetal infection Infectious Diseases 0.885 0.663 – 1.18 0.411 60 301 exclusion phecode
130.1 Lyme disease Infectious Diseases 1.03 0.716 – 1.49 0.862 38 203 exclusion phecode
131 Protozoan infection Infectious Diseases 0.634 0.362 – 1.11 0.111 17 109 exclusion phecode
132 Infestation (lice, mites) Infectious Diseases 0.816 0.636 – 1.05 0.108 73 401 exclusion phecode
134 Helminthiases Infectious Diseases 0.842 0.579 – 1.22 0.367 31 156 exclusion phecode
134.1 Intestinal helminthiases Infectious Diseases 0.906 0.529 – 1.55 0.718 18 114 exclusion phecode
136 Other infectious and parasitic diseases Infectious Diseases 1.01 0.948 – 1.08 0.746 1123 6410 exclusion phecode
145 Cancer of mouth Neoplasms 0.959 0.825 – 1.11 0.588 176 2974 exclusion phecode
145.1 Cancer of lip Neoplasms 0.726 0.386 – 1.36 0.32 9 130 exclusion phecode
145.2 Cancer of tongue Neoplasms 0.911 0.713 – 1.16 0.455 65 1291 exclusion phecode
145.3 Cancer of major salivary glands Neoplasms 1.02 0.775 – 1.35 0.874 54 741 exclusion phecode
145.4 Cancer of the gums Neoplasms 0.454 0.248 – 0.832 0.0107 12 321 exclusion phecode
145.5 Cancer of the mouth floor Neoplasms 1.16 0.773 – 1.73 0.479 18 383 exclusion phecode
149 Cancer of larynx, pharynx, nasal cavities Neoplasms 0.926 0.787 – 1.09 0.354 152 2619 exclusion phecode
149.1 Cancer of oropharynx Neoplasms 0.939 0.712 – 1.24 0.652 53 746 exclusion phecode
149.2 Cancer of nasopharynx Neoplasms 1.18 0.695 – 2 0.541 13 204 exclusion phecode
149.3 Cancer of hypopharynx Neoplasms 1.08 0.597 – 1.94 0.804 8 177 exclusion phecode
149.4 Cancer of larynx Neoplasms 0.816 0.597 – 1.12 0.204 42 796 exclusion phecode
149.5
Hx of malignant neoplasm of oral cavity and
Hx of malignant neoplasm of oral cavity and pharynx
 Neoplasms 0.863 0.698 – 1.07 0.173 85 1120 exclusion phecode
149.9 Cancer of of nasal cavities Neoplasms 1.15 0.748 – 1.77 0.523 23 467 exclusion phecode
150 Cancer of esophagus Neoplasms 0.933 0.733 – 1.19 0.572 69 805 exclusion phecode
151 Cancer of stomach Neoplasms 1 0.816 – 1.23 0.976 93 960 exclusion phecode
153 Colorectal cancer Neoplasms 1.05 0.937 – 1.18 0.396 344 2154 exclusion phecode
153.2 Colon cancer Neoplasms 1.1 0.964 – 1.24 0.163 278 1712 exclusion phecode
153.3
Malignant neoplasm of rectum, rectosigmoid
Malignant neoplasm of rectum, rectosigmoid junction, and anus
 Neoplasms 1.01 0.865 – 1.18 0.911 186 1173 exclusion phecode
155 Cancer of liver and intrahepatic bile duct Neoplasms 1.18 0.966 – 1.44 0.105 119 908 exclusion phecode
155.1 Malignant neoplasm of liver, primary Neoplasms 1.03 0.819 – 1.3 0.802 89 643 exclusion phecode
157 Pancreatic cancer Neoplasms 1.14 0.934 – 1.4 0.192 105 933 exclusion phecode
158
Neoplasm of unspecified nature of digestive
Neoplasm of unspecified nature of digestive system
 Neoplasms 0.983 0.894 – 1.08 0.717 505 3056 exclusion phecode
159
Malignant neoplasm of other and ill-defined
Malignant neoplasm of other and ill-defined sites within the digestive organs and peritoneum
 Neoplasms 1.06 0.958 – 1.17 0.259 440 3215 exclusion phecode
159.2
Malignant neoplasm of small intestine
Malignant neoplasm of small intestine, including duodenum
 Neoplasms 1.09 0.809 – 1.46 0.579 45 409 exclusion phecode
159.3
Malignant neoplasm of gallbladder and
Malignant neoplasm of gallbladder and extrahepatic bile ducts
 Neoplasms 1.02 0.656 – 1.6 0.914 22 330 exclusion phecode
159.4
Malignant neoplasm of retroperitoneum and
Malignant neoplasm of retroperitoneum and peritoneum
 Neoplasms 0.987 0.765 – 1.27 0.918 61 497 exclusion phecode
164 Cancer of intrathoracic organs Neoplasms 1 0.714 – 1.4 0.999 32 266 exclusion phecode
165 Cancer within the respiratory system Neoplasms 1 0.883 – 1.14 0.97 267 2696 exclusion phecode
165.1 Cancer of bronchus; lung Neoplasms 0.974 0.851 – 1.11 0.698 238 2162 exclusion phecode
170 Cancer of bone and connective tissue Neoplasms 0.983 0.859 – 1.12 0.806 224 3471 exclusion phecode
170.1 Bone cancer Neoplasms 0.899 0.734 – 1.1 0.301 99 1447 exclusion phecode
170.2 Cancer of connective tissue Neoplasms 1 0.854 – 1.18 0.965 157 2411 exclusion phecode
172 Skin cancer Neoplasms 0.957 0.906 – 1.01 0.115 1821 6592 exclusion phecode
172.1 Melanomas of skin, dx or hx Neoplasms 0.946 0.887 – 1.01 0.0903 1220 5962 exclusion phecode
172.11 Melanomas of skin Neoplasms 0.883 0.798 – 0.976 0.0149 415 4893 exclusion phecode
172.2 Other non-epithelial cancer of skin Neoplasms 0.951 0.898 – 1.01 0.0845 1641 6121 exclusion phecode
172.21 Basal cell carcinoma Neoplasms 0.984 0.918 – 1.05 0.648 1011 4915 exclusion phecode
172.22 Squamous cell carcinoma Neoplasms 1.01 0.926 – 1.1 0.818 603 3747 exclusion phecode
172.3 Carcinoma in situ of skin Neoplasms 1.05 0.947 – 1.16 0.352 426 2789 exclusion phecode
173 Neoplasm of uncertain behavior of skin Neoplasms 0.999 0.918 – 1.09 0.978 645 4064 exclusion phecode
174 Breast cancer Neoplasms 0.969 0.887 – 1.06 0.485 644 2590 exclusion phecode
174.1 Breast cancer [female] Neoplasms 0.972 0.887 – 1.07 0.548 605 2403 exclusion phecode
174.11 Malignant neoplasm of female breast Neoplasms 0.98 0.893 – 1.08 0.666 592 2376 exclusion phecode
174.3 Neoplasm of uncertain behavior of breast Neoplasms 1.12 0.858 – 1.47 0.398 54 391 exclusion phecode
175 Acquired absence of breast Neoplasms 1.07 0.916 – 1.26 0.382 182 1160 exclusion phecode
180 Cervical cancer and dysplasia Neoplasms 1.03 0.918 – 1.17 0.579 357 1919 exclusion phecode
180.1 Cervical cancer Neoplasms 1.11 0.876 – 1.41 0.382 74 719 exclusion phecode
180.3
Cervical intraepithelial neoplasia [CIN]
Cervical intraepithelial neoplasia [CIN] [Cervical dysplasia]
 Neoplasms 0.991 0.87 – 1.13 0.887 307 1441 exclusion phecode
182 Malignant neoplasm of uterus Neoplasms 1.02 0.852 – 1.22 0.819 133 1214 exclusion phecode
184 Cancer of other female genital organs Neoplasms 1.06 0.924 – 1.21 0.429 243 2012 exclusion phecode
184.1
Malignant neoplasm of ovary and other uterine
Malignant neoplasm of ovary and other uterine adnexa
 Neoplasms 1.05 0.856 – 1.28 0.651 102 982 exclusion phecode
184.11 Malignant neoplasm of ovary Neoplasms 1.09 0.857 – 1.38 0.496 74 734 exclusion phecode
184.2
Cancer of other female genital organs
Cancer of other female genital organs (excluding uterus and ovary)
 Neoplasms 0.969 0.815 – 1.15 0.72 145 1084 exclusion phecode
185 Cancer of prostate Neoplasms 0.962 0.868 – 1.07 0.456 542 2021 exclusion phecode
187 Cancer of other male genital organs Neoplasms 1.04 0.826 – 1.3 0.755 75 724 exclusion phecode
187.1
Malignant neoplasm of unspecified male genital
Malignant neoplasm of unspecified male genital organ
 Neoplasms 1.27 0.812 – 1.97 0.298 21 249 exclusion phecode
187.2 Malignant neoplasm of testis Neoplasms 1.15 0.816 – 1.63 0.418 36 355 exclusion phecode
187.8
Neoplasm of uncertain behavior of male genital
Neoplasm of uncertain behavior of male genital organs
 Neoplasms 0.762 0.483 – 1.2 0.241 24 138 exclusion phecode
189
Cancer of urinary organs (incl. kidney and
Cancer of urinary organs (incl. kidney and bladder)
 Neoplasms 1.02 0.93 – 1.11 0.731 564 4858 exclusion phecode
189.1 Cancer of kidney and renal pelvis Neoplasms 0.979 0.865 – 1.11 0.737 272 3046 exclusion phecode
189.11 Malignant neoplasm of kidney, except pelvis Neoplasms 1 0.875 – 1.15 0.985 229 2649 exclusion phecode
189.12 Malignant neoplasm of renal pelvis Neoplasms 0.914 0.685 – 1.22 0.543 45 541 exclusion phecode
189.2 Cancer of bladder Neoplasms 1.04 0.93 – 1.16 0.497 354 3303 exclusion phecode
189.21 Malignant neoplasm of bladder Neoplasms 1.03 0.919 – 1.16 0.583 313 3088 exclusion phecode
189.4 Malignant neoplasm of other urinary organs Neoplasms 1.16 0.973 – 1.39 0.0968 132 1446 exclusion phecode
190 Cancer of eye Neoplasms 0.827 0.531 – 1.29 0.401 25 269 exclusion phecode
191
Manlignant and unknown neoplasms of brain and
Manlignant and unknown neoplasms of brain and nervous system
 Neoplasms 1.05 0.887 – 1.24 0.579 156 1935 exclusion phecode
191.1 Cancer of brain and nervous system Neoplasms 1.03 0.831 – 1.27 0.81 92 1242 exclusion phecode
191.11 Cancer of brain Neoplasms 1.06 0.837 – 1.34 0.638 73 1025 exclusion phecode
193 Thyroid cancer Neoplasms 1.03 0.877 – 1.21 0.719 162 1804 exclusion phecode
194 Cancer of other endocrine glands Neoplasms 1.14 0.946 – 1.37 0.17 121 1191 exclusion phecode
195 Cancer, suspected or other Neoplasms 1.03 0.981 – 1.08 0.241 3427 5196 exclusion phecode
195.1 Malignant neoplasm, other Neoplasms 1.03 0.981 – 1.08 0.252 3391 5188 exclusion phecode
195.3 Malignant neoplasm of head, face, and neck Neoplasms 0.95 0.811 – 1.11 0.52 168 1912 exclusion phecode
196 Radiotherapy Neoplasms 1.01 0.922 – 1.11 0.812 550 3273 exclusion phecode
197 Chemotherapy Neoplasms 1.06 0.99 – 1.14 0.0926 1033 4586 exclusion phecode
198 Secondary malignant neoplasm Neoplasms 1.08 0.998 – 1.16 0.0551 866 4413 exclusion phecode
198.1 Secondary malignancy of lymph nodes Neoplasms 1.09 0.988 – 1.2 0.087 482 3986 exclusion phecode
198.2 Secondary malignancy of respiratory organs Neoplasms 1.05 0.906 – 1.23 0.494 187 1946 exclusion phecode
198.3
Secondary malignant neoplasm of digestive
Secondary malignant neoplasm of digestive systems
 Neoplasms 1.03 0.875 – 1.22 0.704 151 1569 exclusion phecode
198.4 Secondary malignant neoplasm of liver Neoplasms 1.04 0.873 – 1.24 0.655 134 1459 exclusion phecode
198.5 Secondary malignancy of brain/spine Neoplasms 1.08 0.871 – 1.33 0.501 89 1150 exclusion phecode
198.6 Secondary malignancy of bone Neoplasms 1.16 0.986 – 1.37 0.0726 161 1559 exclusion phecode
198.7 Secondary malignant neoplasm of skin Neoplasms 1.03 0.79 – 1.35 0.823 52 691 exclusion phecode
199 Neoplasm of uncertain behavior Neoplasms 1.05 0.984 – 1.11 0.147 1372 5086 exclusion phecode
199.4 Neurofibromatosis Neoplasms 1.52 0.848 – 2.74 0.159 11 156 exclusion phecode
200 Myeloproliferative disease Neoplasms 1.08 0.977 – 1.2 0.131 441 2412 exclusion phecode
200.1 Polycythemia vera Neoplasms 1.13 0.926 – 1.37 0.231 117 527 exclusion phecode
201 Hodgkin's disease Neoplasms 1.04 0.79 – 1.36 0.788 57 345 exclusion phecode
202 Cancer of other lymphoid, histiocytic tissue Neoplasms 0.99 0.889 – 1.1 0.862 378 3215 exclusion phecode
202.2 Non-Hodgkins lymphoma Neoplasms 0.973 0.865 – 1.09 0.649 314 2764 exclusion phecode
202.21 Nodular lymphoma Neoplasms 0.943 0.802 – 1.11 0.476 158 1411 exclusion phecode
202.22 Reticulosarcoma Neoplasms 1.13 0.829 – 1.53 0.446 43 375 exclusion phecode
202.24 Large cell lymphoma Neoplasms 1.41 1.01 – 1.97 0.0417 36 342 exclusion phecode
204 Leukemia Neoplasms 1.04 0.909 – 1.2 0.537 240 1578 exclusion phecode
204.1 Lymphoid leukemia Neoplasms 0.985 0.758 – 1.28 0.908 63 517 exclusion phecode
204.11 Lymphoid leukemia, acute Neoplasms 1.03 0.688 – 1.53 0.901 27 158 exclusion phecode
204.12 Lymphoid leukemia, chronic Neoplasms 0.998 0.738 – 1.35 0.992 46 386 exclusion phecode
204.2 Myeloid leukemia Neoplasms 1.15 0.934 – 1.4 0.191 121 663 exclusion phecode
204.21 Myeloid leukemia, acute Neoplasms 1.06 0.806 – 1.38 0.696 72 389 exclusion phecode
204.22 Myeloid leukemia, chronic Neoplasms 1.14 0.742 – 1.75 0.55 23 135 exclusion phecode
204.4 Multiple myeloma Neoplasms 0.922 0.722 – 1.18 0.516 77 503 exclusion phecode
208 Benign neoplasm of colon Neoplasms 0.994 0.951 – 1.04 0.769 3725 5595 exclusion phecode
209 Neuroendocrine tumors Neoplasms 1.11 0.86 – 1.43 0.428 63 546 exclusion phecode
210 Benign neoplasm of lip, oral cavity, and pharynx Neoplasms 0.934 0.828 – 1.05 0.264 295 3630 exclusion phecode
211
Benign neoplasm of other parts of digestive
Benign neoplasm of other parts of digestive system
 Neoplasms 1.01 0.96 – 1.05 0.801 2509 6533 exclusion phecode
212
Benign neoplasm of respiratory and
Benign neoplasm of respiratory and intrathoracic organs
 Neoplasms 1.07 0.966 – 1.19 0.188 391 3505 exclusion phecode
213 Benign neoplasm of bone and articular cartilage Neoplasms 0.945 0.839 – 1.06 0.351 332 2266 exclusion phecode
214 Lipoma Neoplasms 1.08 0.975 – 1.19 0.143 459 2915 exclusion phecode
214.1 Lipoma of skin and subcutaneous tissue Neoplasms 1.08 0.949 – 1.22 0.25 280 1774 exclusion phecode
215
Other benign neoplasm of connective and other
Other benign neoplasm of connective and other soft tissue
 Neoplasms 0.98 0.918 – 1.05 0.549 1054 7625 exclusion phecode
216 Benign neoplasm of skin Neoplasms 0.965 0.925 – 1.01 0.0997 3606 5974 exclusion phecode
216.1 Screening for malignant neoplasms of the skin Neoplasms 0.791 0.602 – 1.04 0.0917 68 309 exclusion phecode
217 Vascular hamartomas and non-neoplastic nevi Neoplasms 0.918 0.841 – 1 0.0516 645 3218 exclusion phecode
217.1 Nevus, non-neoplastic Neoplasms 0.913 0.836 – 0.996 0.0413 623 3080 exclusion phecode
218 Benign neoplasm of uterus Neoplasms 0.913 0.851 – 0.979 0.0107 1199 2769 exclusion phecode
218.1 Uterine leiomyoma Neoplasms 0.862 0.781 – 0.951 0.00312 494 2563 exclusion phecode
218.2 Other benign neoplasm of uterus Neoplasms 0.9 0.834 – 0.971 0.0066 967 2696 exclusion phecode
220 Benign neoplasm of ovary Neoplasms 0.921 0.794 – 1.07 0.273 206 1249 exclusion phecode
221 Benign neoplasm of other female genital organs Neoplasms 0.891 0.803 – 0.988 0.0285 445 2224 exclusion phecode
222 Benign neoplasm of male genital organs Neoplasms 0.967 0.856 – 1.09 0.583 297 2486 exclusion phecode
223
Benign neoplasm of kidney and other urinary
Benign neoplasm of kidney and other urinary organs
 Neoplasms 1.07 0.952 – 1.2 0.265 370 1867 exclusion phecode
224 Benign neoplasm of eye Neoplasms 0.963 0.847 – 1.09 0.562 283 1709 exclusion phecode
224.1 Benign neoplasm of eye, uveal Neoplasms 0.987 0.863 – 1.13 0.851 257 1504 exclusion phecode
225
Benign neoplasm of brain and other parts of
Benign neoplasm of brain and other parts of nervous system
 Neoplasms 0.972 0.842 – 1.12 0.692 204 2269 exclusion phecode
225.1
Benign neoplasm of brain, cranial nerves
Benign neoplasm of brain, cranial nerves, meninges
 Neoplasms 1.04 0.875 – 1.23 0.68 145 1751 exclusion phecode
225.2 Benign neoplasm of spinal cord, meninges Neoplasms 0.838 0.639 – 1.1 0.202 58 537 exclusion phecode
226 Benign neoplasm of thyroid glands Neoplasms 1.03 0.919 – 1.16 0.582 312 2658 exclusion phecode
227
Benign neoplasm of other endocrine glands and
Benign neoplasm of other endocrine glands and related structures
 Neoplasms 1.07 0.957 – 1.2 0.227 327 3275 exclusion phecode
227.1 Benign neoplasm of adrenal gland Neoplasms 1.26 1.05 – 1.51 0.0128 137 1018 exclusion phecode
227.2 Benign neoplasm of parathyroid gland Neoplasms 1.06 0.885 – 1.28 0.513 133 1391 exclusion phecode
227.3
Benign neoplasm of pituitary gland and
Benign neoplasm of pituitary gland and craniopharyngeal duct (pouch)
 Neoplasms 0.993 0.775 – 1.27 0.959 63 870 exclusion phecode
228 Hemangioma and lymphangioma, any site Neoplasms 0.991 0.915 – 1.07 0.825 709 4626 exclusion phecode
228.1 Hemangioma of skin and subcutaneous tissue Neoplasms 0.922 0.836 – 1.02 0.0998 494 3047 exclusion phecode
229 Benign neoplasm of unspecified sites Neoplasms 1.03 0.968 – 1.09 0.368 1244 7465 exclusion phecode
229.1 Benign neoplasm of lymph nodes Neoplasms 1.05 0.974 – 1.14 0.2 724 6719 exclusion phecode
240 Simple and unspecified goiter Endocrine/metabolic 1 0.894 – 1.13 0.936 337 2007 exclusion phecode
241 Nontoxic nodular goiter Endocrine/metabolic 0.98 0.909 – 1.06 0.591 828 4383 exclusion phecode
241.1 Nontoxic uninodular goiter Endocrine/metabolic 0.985 0.906 – 1.07 0.724 663 3845 exclusion phecode
241.2 Nontoxic multinodular goiter Endocrine/metabolic 1.01 0.905 – 1.12 0.897 383 2424 exclusion phecode
242 Thyrotoxicosis with or without goiter Endocrine/metabolic 0.989 0.897 – 1.09 0.826 466 2750 exclusion phecode
242.1 Graves' disease Endocrine/metabolic 0.984 0.826 – 1.17 0.857 137 1024 exclusion phecode
242.2 Toxic multinodular goiter Endocrine/metabolic 1.36 0.949 – 1.95 0.094 36 262 exclusion phecode
242.3 Exophthalmos Endocrine/metabolic 1.12 0.886 – 1.4 0.353 79 577 exclusion phecode
242.31 Thyrotoxic exophthalmos Endocrine/metabolic 0.749 0.518 – 1.08 0.124 33 262 exclusion phecode
244 Hypothyroidism Endocrine/metabolic 0.994 0.944 – 1.05 0.829 2072 6377 exclusion phecode
244.1 Secondary hypothyroidism Endocrine/metabolic 0.987 0.89 – 1.09 0.801 402 3305 exclusion phecode
244.2 Acquired hypothyroidism Endocrine/metabolic 1.09 0.988 – 1.21 0.0861 441 2531 exclusion phecode
244.4 Hypothyroidism NOS Endocrine/metabolic 0.989 0.938 – 1.04 0.668 1995 6295 exclusion phecode
245 Thyroiditis Endocrine/metabolic 1.02 0.893 – 1.16 0.806 260 1745 exclusion phecode
245.2 Chronic thyroiditis Endocrine/metabolic 1.03 0.893 – 1.19 0.674 217 1448 exclusion phecode
245.21 Chronic lymphocytic thyroiditis Endocrine/metabolic 1.02 0.883 – 1.18 0.798 216 1447 exclusion phecode
246 Other disorders of thyroid Endocrine/metabolic 0.972 0.917 – 1.03 0.348 1482 5893 exclusion phecode
246.2 Thyroid cyst Endocrine/metabolic 0.811 0.543 – 1.21 0.304 31 197 exclusion phecode
246.7 Abnormal results of function study of thyroid Endocrine/metabolic 1.03 0.922 – 1.15 0.608 354 1926 exclusion phecode
249 Secondary diabetes mellitus Endocrine/metabolic 1.07 0.959 – 1.18 0.234 691 1087 exclusion phecode
250 Diabetes mellitus Endocrine/metabolic 1.05 1.01 – 1.1 0.024 5139 4378 exclusion phecode
250.1 Type 1 diabetes Endocrine/metabolic 1.04 0.953 – 1.14 0.373 1559 1539 exclusion phecode
250.11 Type 1 diabetes with ketoacidosis Endocrine/metabolic 0.953 0.752 – 1.21 0.693 175 146 exclusion phecode
250.12 Type 1 diabetes with renal manifestations Endocrine/metabolic 0.923 0.778 – 1.09 0.352 391 391 exclusion phecode
250.13 Type 1 diabetes with ophthalmic manifestations Endocrine/metabolic 1.05 0.894 – 1.23 0.571 566 411 exclusion phecode
250.14 Type 1 diabetes with neurological manifestations Endocrine/metabolic 1.03 0.874 – 1.22 0.708 462 364 exclusion phecode
250.15
Diabetes type 1 with peripheral circulatory
Diabetes type 1 with peripheral circulatory disorders
 Endocrine/metabolic 0.876 0.654 – 1.17 0.373 123 117 exclusion phecode
250.2 Type 2 diabetes Endocrine/metabolic 1.07 1.02 – 1.13 0.00891 3804 4047 exclusion phecode
250.21 Type 2 diabetes with ketoacidosis Endocrine/metabolic 1.03 0.815 – 1.3 0.803 181 181 exclusion phecode
250.22 Type 2 diabetes with renal manifestations Endocrine/metabolic 1.11 1.02 – 1.2 0.0158 1254 1797 exclusion phecode
250.23 Type 2 diabetes with ophthalmic manifestations Endocrine/metabolic 0.983 0.894 – 1.08 0.716 1123 1301 exclusion phecode
250.24 Type 2 diabetes with neurological manifestations Endocrine/metabolic 1.09 1.01 – 1.18 0.0225 1590 2173 exclusion phecode
250.25
Diabetes type 2 with peripheral circulatory
Diabetes type 2 with peripheral circulatory disorders
 Endocrine/metabolic 1.1 0.979 – 1.23 0.109 593 876 exclusion phecode
250.3 Insulin pump user Endocrine/metabolic 1.1 1.02 – 1.17 0.00991 2021 2716 exclusion phecode
250.4 Abnormal glucose Endocrine/metabolic 1.05 0.999 – 1.1 0.0561 3800 4234 exclusion phecode
250.41 Impaired fasting glucose Endocrine/metabolic 1 0.922 – 1.09 0.911 833 2258 exclusion phecode
250.42 Other abnormal glucose Endocrine/metabolic 1.06 1.01 – 1.12 0.0314 3471 4153 exclusion phecode
250.5 Glycosuria or Acetonuria Endocrine/metabolic 0.895 0.65 – 1.23 0.498 63 166 exclusion phecode
250.6 Polyneuropathy in diabetes Endocrine/metabolic 1.05 0.97 – 1.15 0.211 1388 1776 exclusion phecode
250.7 Diabetic retinopathy Endocrine/metabolic 0.996 0.925 – 1.07 0.916 1153 2114 exclusion phecode
251 Other disorders of pancreatic internal secretion Endocrine/metabolic 1.03 0.937 – 1.14 0.504 510 1961 exclusion phecode
251.1 Hypoglycemia Endocrine/metabolic 1.11 0.992 – 1.25 0.0681 653 1107 exclusion phecode
252 Disorders of parathyroid gland Endocrine/metabolic 1.07 0.988 – 1.16 0.0951 752 3989 exclusion phecode
252.1 Hyperparathyroidism Endocrine/metabolic 1.09 1 – 1.18 0.0455 702 3700 exclusion phecode
252.2 Hypoparathyroidism Endocrine/metabolic 1.08 0.905 – 1.3 0.384 136 871 exclusion phecode
253
Disorders of the pituitary gland and its
Disorders of the pituitary gland and its hypothalamic control
 Endocrine/metabolic 1.04 0.911 – 1.19 0.548 242 1739 exclusion phecode
253.1 Pituitary hyperfunction Endocrine/metabolic 1.05 0.821 – 1.35 0.678 69 537 exclusion phecode
253.11 Acromegaly and gigantism Endocrine/metabolic 1.27 0.756 – 2.15 0.363 12 144 exclusion phecode
253.2 Pituitary hypofunction Endocrine/metabolic 1.15 0.85 – 1.56 0.361 45 419 exclusion phecode
253.3 Diabetes insipidus Endocrine/metabolic 1.04 0.699 – 1.55 0.841 33 191 exclusion phecode
253.4 Anterior pituitary disorders Endocrine/metabolic 0.868 0.633 – 1.19 0.38 48 309 exclusion phecode
253.7 Other disorders of neurohypophysis Endocrine/metabolic 1.15 0.847 – 1.56 0.373 40 201 exclusion phecode
255 Disorders of adrenal glands Endocrine/metabolic 1.01 0.917 – 1.12 0.789 459 2954 exclusion phecode
255.1 Adrenal hyperfunction Endocrine/metabolic 1.01 0.831 – 1.22 0.94 118 715 exclusion phecode
255.11 Cushing's syndrome Endocrine/metabolic 1.03 0.764 – 1.39 0.84 48 361 exclusion phecode
255.12 Hyperaldosteronism Endocrine/metabolic 1.14 0.826 – 1.56 0.433 42 270 exclusion phecode
255.2 Adrenal hypofunction Endocrine/metabolic 1.12 0.965 – 1.31 0.134 194 1232 exclusion phecode
255.21 Glucocorticoid deficiency Endocrine/metabolic 1.09 0.935 – 1.28 0.263 185 1168 exclusion phecode
256 Ovarian dysfunction Endocrine/metabolic 0.921 0.823 – 1.03 0.151 387 1873 exclusion phecode
256.4 Polycystic ovaries Endocrine/metabolic 0.942 0.822 – 1.08 0.385 264 1315 exclusion phecode
257 Testicular dysfunction Endocrine/metabolic 0.98 0.884 – 1.09 0.708 460 1943 exclusion phecode
257.1 Testicular hypofunction Endocrine/metabolic 0.989 0.89 – 1.1 0.829 447 1876 exclusion phecode
258 Iatrogenic endocrine disorders Endocrine/metabolic 1.11 0.768 – 1.62 0.571 34 227 exclusion phecode
258.1 Postablative ovarian failure Endocrine/metabolic 0.984 0.69 – 1.4 0.928 38 180 exclusion phecode
259 Other endocrine disorders Endocrine/metabolic 1.05 0.937 – 1.17 0.428 388 2138 exclusion phecode
260 Protein-calorie malnutrition Endocrine/metabolic 1.12 1.05 – 1.21 0.00168 888 4113 exclusion phecode
260.1 Cachexia Endocrine/metabolic 1.26 0.999 – 1.58 0.0515 85 434 exclusion phecode
260.2 severe protein-calorie malnutrition Endocrine/metabolic 1.12 1.02 – 1.23 0.0215 504 2601 exclusion phecode
260.22 Nutritional marasmus Endocrine/metabolic 1.1 0.94 – 1.28 0.243 197 956 exclusion phecode
260.3 Adult failure to thrive Endocrine/metabolic 1.11 0.953 – 1.28 0.186 215 1006 exclusion phecode
260.6 Anorexia Endocrine/metabolic 1.04 0.914 – 1.18 0.576 299 1455 exclusion phecode
260.7 Polyphagia Endocrine/metabolic 1.19 0.758 – 1.88 0.443 28 186 exclusion phecode
261 Vitamin deficiency Endocrine/metabolic 1.01 0.963 – 1.05 0.737 3082 5515 exclusion phecode
261.1 Vitamin A deficiency Endocrine/metabolic 1.1 0.755 – 1.59 0.626 33 147 exclusion phecode
261.2 Vitamin B-complex deficiencies Endocrine/metabolic 1.05 0.936 – 1.19 0.387 345 1474 exclusion phecode
261.4 Vitamin D deficiency Endocrine/metabolic 1.01 0.964 – 1.06 0.686 2923 5517 exclusion phecode
261.41 Rickets or osteomalacia Endocrine/metabolic 1.02 0.58 – 1.81 0.934 18 76 exclusion phecode
262 Mineral deficiency NEC Endocrine/metabolic 1.05 0.959 – 1.16 0.277 583 2068 exclusion phecode
263 Other nutritional deficiency Endocrine/metabolic 1.02 0.93 – 1.11 0.736 629 2700 exclusion phecode
264 Lack of normal physiological development Endocrine/metabolic 1.17 0.91 – 1.5 0.224 87 362 exclusion phecode
264.2 Failure to thrive (childhood) Endocrine/metabolic 1 0.729 – 1.38 0.985 40 188 exclusion phecode
264.9
Lack of normal physiological development
Lack of normal physiological development, unspecified
 Endocrine/metabolic 1.95 1.16 – 3.3 0.012 31 117 exclusion phecode
269 Proteinuria Endocrine/metabolic 1.11 1.03 – 1.19 0.00504 1040 3071 exclusion phecode
270
Disorders of protein plasma/amino-acid
Disorders of protein plasma/amino-acid transport and metabolism
 Endocrine/metabolic 1.02 0.91 – 1.14 0.774 393 1961 exclusion phecode
270.1 Disturbances of amino-acid transport Endocrine/metabolic 0.832 0.603 – 1.15 0.264 42 308 exclusion phecode
270.11
Disturbances of sulphur-bearing amino-acid
Disturbances of sulphur-bearing amino-acid metabolism
 Endocrine/metabolic 0.827 0.567 – 1.21 0.324 31 259 exclusion phecode
270.2 Disorders of amino-acid metabolism Endocrine/metabolic 0.866 0.624 – 1.2 0.389 47 207 exclusion phecode
270.3 Disorders of plasma protein metabolism Endocrine/metabolic 1.07 0.94 – 1.21 0.322 321 1539 exclusion phecode
270.32 Paraproteinemia Endocrine/metabolic 1.07 0.9 – 1.27 0.439 173 844 exclusion phecode
270.33 Amyloidosis Endocrine/metabolic 1.81 1.12 – 2.91 0.0154 23 142 exclusion phecode
270.34 Alpha-1-antitrypsin deficiency Endocrine/metabolic 1.03 0.7 – 1.53 0.864 28 154 exclusion phecode
270.38
Other specified disorders of plasma protein
Other specified disorders of plasma protein metabolism
 Endocrine/metabolic 1.07 0.882 – 1.31 0.482 132 574 exclusion phecode
271
Disorders of carbohydrate transport and
Disorders of carbohydrate transport and metabolism
 Endocrine/metabolic 0.93 0.87 – 0.994 0.0337 1033 5694 exclusion phecode
271.3
Intestinal disaccharidase deficiencies and
Intestinal disaccharidase deficiencies and disaccharide malabsorption
 Endocrine/metabolic 0.933 0.871 – 0.998 0.0451 1004 5551 exclusion phecode
271.9
Other disorders of carbohydrate transport and
Other disorders of carbohydrate transport and metabolism
 Endocrine/metabolic 0.835 0.614 – 1.13 0.248 39 229 exclusion phecode
272 Disorders of lipoid metabolism Endocrine/metabolic 1.36 1.29 – 1.43 1.08e-31 5679 3855 exclusion phecode
272.1 Hyperlipidemia Endocrine/metabolic 1.37 1.3 – 1.44 3.21e-32 5668 3853 exclusion phecode
272.11 Hypercholesterolemia Endocrine/metabolic 1.58 1.47 – 1.7 3.71e-34 2064 3096 exclusion phecode
272.12 Hyperglyceridemia Endocrine/metabolic 1.38 1.25 – 1.51 6.97e-11 712 1661 exclusion phecode
272.13 Mixed hyperlipidemia Endocrine/metabolic 1.54 1.43 – 1.66 5.57e-29 1744 2534 exclusion phecode
272.9 Unspecified disorder of lipoid metabolism Endocrine/metabolic 1.37 1.1 – 1.72 0.00585 125 427 exclusion phecode
274 Gout and other crystal arthropathies Endocrine/metabolic 1.06 0.992 – 1.14 0.0855 1021 4780 exclusion phecode
274.1 Gout Endocrine/metabolic 1.07 0.996 – 1.14 0.0629 977 4652 exclusion phecode
274.11 Gouty arthropathy Endocrine/metabolic 1.06 0.964 – 1.16 0.236 565 2505 exclusion phecode
274.2 Crystal arthropathies Endocrine/metabolic 1.08 0.852 – 1.38 0.518 82 410 exclusion phecode
274.21 Chondrocalcinosis Endocrine/metabolic 1.05 0.823 – 1.34 0.7 76 380 exclusion phecode
275 Disorders of mineral metabolism Endocrine/metabolic 1.03 0.977 – 1.09 0.257 1628 7003 exclusion phecode
275.1 Disorders of iron metabolism Hematopoietic 0.778 0.609 – 0.995 0.0459 84 443 exclusion phecode
275.11 Hereditary hemochromatosis Hematopoietic 0.612 0.414 – 0.904 0.0137 34 222 exclusion phecode
275.2 Disorders of copper metabolism Endocrine/metabolic 0.983 0.661 – 1.46 0.931 30 137 exclusion phecode
275.3 Disorders of magnesium metabolism Endocrine/metabolic 1.07 0.969 – 1.18 0.178 487 2346 exclusion phecode
275.5 Disorders of calcium/phosphorus metabolism Endocrine/metabolic 1.03 0.968 – 1.09 0.355 1242 5996 exclusion phecode
275.51 Hypocalcemia Endocrine/metabolic 1 0.888 – 1.13 0.969 305 1668 exclusion phecode
275.53 Disorders of phosphorus metabolism Endocrine/metabolic 1.03 0.943 – 1.13 0.495 580 2623 exclusion phecode
275.6 Hypercalcemia Endocrine/metabolic 1.04 0.952 – 1.14 0.368 585 3003 exclusion phecode
276
Disorders of fluid, electrolyte, and acid-base
Disorders of fluid, electrolyte, and acid-base balance
 Endocrine/metabolic 1.06 1.01 – 1.11 0.00919 3458 6053 exclusion phecode
276.1 Electrolyte imbalance Endocrine/metabolic 1.06 1.01 – 1.11 0.0253 2564 5636 exclusion phecode
276.11 Hyperosmolality and/or hypernatremia Endocrine/metabolic 1.02 0.885 – 1.17 0.82 262 1017 exclusion phecode
276.12 Hyposmolality and/or hyponatremia Endocrine/metabolic 1.05 0.982 – 1.13 0.146 1050 3848 exclusion phecode
276.13 Hyperpotassemia Endocrine/metabolic 1.07 1.01 – 1.14 0.0198 1407 4299 exclusion phecode
276.14 Hypopotassemia Endocrine/metabolic 1.01 0.939 – 1.09 0.753 865 3516 exclusion phecode
276.4 Acid-base balance disorder Endocrine/metabolic 1.1 1.02 – 1.18 0.0106 999 3475 exclusion phecode
276.41 Acidosis Endocrine/metabolic 1.1 1.01 – 1.18 0.0194 871 3067 exclusion phecode
276.42 Alkalosis Endocrine/metabolic 1.1 0.948 – 1.27 0.211 222 885 exclusion phecode
276.5 Hypovolemia Endocrine/metabolic 1.1 1.04 – 1.17 0.000439 1733 5592 exclusion phecode
276.6 Fluid overload Endocrine/metabolic 1.01 0.927 – 1.09 0.88 777 2360 exclusion phecode
276.8 Polydipsia Endocrine/metabolic 1.11 0.797 – 1.53 0.549 48 243 exclusion phecode
277 Other disorders of metabolism Endocrine/metabolic 1.04 0.987 – 1.1 0.137 1698 6591 exclusion phecode
277.2
Other disorders of purine and pyrimidine
Other disorders of purine and pyrimidine metabolism
 Endocrine/metabolic 1.08 0.922 – 1.27 0.339 206 1102 exclusion phecode
277.4 Disorders of bilirubin excretion Endocrine/metabolic 1.01 0.886 – 1.15 0.908 301 1459 exclusion phecode
277.5 Other disorders of lipoid metabolism Endocrine/metabolic 0.992 0.894 – 1.1 0.881 434 2099 exclusion phecode
277.51 Lipoprotein disorders Endocrine/metabolic 0.995 0.887 – 1.12 0.925 364 1753 exclusion phecode
277.7 Dysmetabolic syndrome X Endocrine/metabolic 1.05 0.953 – 1.17 0.304 478 2058 exclusion phecode
278 Overweight, obesity and other hyperalimentation Endocrine/metabolic 0.973 0.934 – 1.01 0.199 5231 4434 exclusion phecode
278.1 Obesity Endocrine/metabolic 0.965 0.925 – 1.01 0.103 4572 4431 exclusion phecode
278.11 Morbid obesity Endocrine/metabolic 0.967 0.919 – 1.02 0.191 2451 4374 exclusion phecode
278.3 Localized adiposity Endocrine/metabolic 0.892 0.731 – 1.09 0.263 130 546 exclusion phecode
278.4 Abnormal weight gain Endocrine/metabolic 0.971 0.897 – 1.05 0.477 844 2845 exclusion phecode
279 Disorders involving the immune mechanism Endocrine/metabolic 1 0.943 – 1.07 0.898 1247 5013 exclusion phecode
279.1 Immunity deficiency Endocrine/metabolic 1.06 0.96 – 1.17 0.249 527 2081 exclusion phecode
279.11 Deficiency of humoral immunity Endocrine/metabolic 1.09 0.888 – 1.33 0.424 128 636 exclusion phecode
279.2 Autoimmune disease NEC Endocrine/metabolic 0.983 0.863 – 1.12 0.79 270 1441 exclusion phecode
279.7 Other immunological findings Endocrine/metabolic 1.03 0.982 – 1.09 0.204 2058 6405 exclusion phecode
279.8
Other specified disorders involving the immune
Other specified disorders involving the immune mechanism
 Endocrine/metabolic 1.01 0.874 – 1.16 0.93 231 1146 exclusion phecode
280 Iron deficiency anemias Hematopoietic 1.13 1.07 – 1.19 7.96e-06 1997 4825 exclusion phecode
280.1
Iron deficiency anemias, unspecified or not due
Iron deficiency anemias, unspecified or not due to blood loss
 Hematopoietic 1.12 1.06 – 1.19 3.08e-05 1938 4789 exclusion phecode
280.2
Iron deficiency anemia secondary to blood loss
Iron deficiency anemia secondary to blood loss (chronic)
 Hematopoietic 1.1 1.01 – 1.19 0.0293 781 2762 exclusion phecode
281 Other deficiency anemia Hematopoietic 1.13 0.979 – 1.31 0.0923 240 834 exclusion phecode
281.1 Megaloblastic anemia Hematopoietic 1.18 0.959 – 1.46 0.116 108 422 exclusion phecode
281.11 Pernicious anemia Hematopoietic 1.3 0.938 – 1.79 0.116 51 199 exclusion phecode
281.12 Other vitamin B12 deficiency anemia Hematopoietic 1.23 0.955 – 1.58 0.109 73 310 exclusion phecode
281.9 Deficiency anemias Hematopoietic 1.14 0.94 – 1.38 0.183 149 451 exclusion phecode
282 Hereditary hemolytic anemias Hematopoietic 1.02 0.838 – 1.25 0.817 134 557 exclusion phecode
282.8 Other hemoglobinopathies Hematopoietic 1.03 0.815 – 1.31 0.789 91 414 exclusion phecode
282.9 Other hereditary hemolytic anemias Hematopoietic 1.13 0.883 – 1.44 0.336 86 342 exclusion phecode
283 Acquired hemolytic anemias Hematopoietic 1.01 0.757 – 1.34 0.955 77 286 exclusion phecode
283.1 Autoimmune hemolytic anemias Hematopoietic 0.801 0.523 – 1.23 0.306 30 122 exclusion phecode
284 Aplastic anemia Hematopoietic 1.17 1.03 – 1.33 0.0173 314 1151 exclusion phecode
284.1 Pancytopenia Hematopoietic 1.16 1.01 – 1.34 0.0353 272 1006 exclusion phecode
285 Other anemias Hematopoietic 1.09 1.04 – 1.14 0.000106 4012 5235 exclusion phecode
285.1 Acute posthemorrhagic anemia Hematopoietic 1.15 1.07 – 1.22 5.61e-05 1210 4141 exclusion phecode
285.2 Anemia of chronic disease Hematopoietic 1.1 1.02 – 1.19 0.00985 957 3176 exclusion phecode
285.21 Anemia in chronic kidney disease Hematopoietic 1.06 0.963 – 1.17 0.23 589 1688 exclusion phecode
285.22 Anemia in neoplastic disease Hematopoietic 1.11 0.944 – 1.31 0.203 179 955 exclusion phecode
286 Coagulation defects Hematopoietic 1.08 1.02 – 1.15 0.0111 1401 5809 exclusion phecode
286.1 Congenital coagulation defects Hematopoietic 0.929 0.716 – 1.21 0.579 71 465 exclusion phecode
286.11 Von willebrand's disease Hematopoietic 1.04 0.642 – 1.69 0.867 19 157 exclusion phecode
286.12
Congenital deficiency of other clotting factors
Congenital deficiency of other clotting factors (including factor VII)
 Hematopoietic 0.913 0.64 – 1.3 0.616 36 250 exclusion phecode
286.2
Encounter for long-term (current) use of
Encounter for long-term (current) use of anticoagulants
 Hematopoietic 1.1 1.03 – 1.17 0.00282 1406 4555 exclusion phecode
286.3
Coagulation defects complicating pregnancy or
Coagulation defects complicating pregnancy or postpartum
 Hematopoietic 0.701 0.478 – 1.03 0.0694 33 216 exclusion phecode
286.4 Acquired coagulation factor deficiency Hematopoietic 0.94 0.763 – 1.16 0.556 118 492 exclusion phecode
286.5
Hemorrhagic disorder due to intrinsic
Hemorrhagic disorder due to intrinsic circulating anticoagulants
 Hematopoietic 1.12 0.848 – 1.49 0.415 61 269 exclusion phecode
286.6 Defibrination syndrome Hematopoietic 1.1 1.03 – 1.19 0.00762 892 4540 exclusion phecode
286.7 Other and unspecified coagulation defects Hematopoietic 1.09 1.02 – 1.16 0.012 1077 5172 exclusion phecode
286.8 Hypercoagulable state Hematopoietic 1.04 0.906 – 1.19 0.589 244 1533 exclusion phecode
286.81 Primary hypercoagulable state Hematopoietic 1.02 0.891 – 1.18 0.74 234 1475 exclusion phecode
286.9 Abnormal coagulation profile Hematopoietic 1.06 0.965 – 1.17 0.225 557 2114 exclusion phecode
287 Purpura and other hemorrhagic conditions Hematopoietic 1.14 1.07 – 1.22 2.64e-05 1326 5057 exclusion phecode
287.1 Spontaneous ecchymoses Hematopoietic 1.07 0.847 – 1.36 0.565 82 401 exclusion phecode
287.3 Thrombocytopenia Hematopoietic 1.15 1.08 – 1.23 1.61e-05 1203 4696 exclusion phecode
287.31 Primary thrombocytopenia Hematopoietic 1.17 1 – 1.38 0.0504 189 1070 exclusion phecode
287.32 Secondary thrombocytopenia Hematopoietic 1.14 0.985 – 1.32 0.0794 208 1015 exclusion phecode
287.4 Qualitative platelet defects Hematopoietic 1.3 0.906 – 1.85 0.156 39 205 exclusion phecode
288 Diseases of white blood cells Hematopoietic 1.04 0.988 – 1.1 0.134 1829 6382 exclusion phecode
288.1 Decreased white blood cell count Hematopoietic 1.07 0.972 – 1.17 0.176 572 2808 exclusion phecode
288.11 Neutropenia Hematopoietic 1.07 0.956 – 1.2 0.238 378 1937 exclusion phecode
288.2 Elevated white blood cell count Hematopoietic 1.03 0.978 – 1.09 0.234 1606 6166 exclusion phecode
288.3 Eosinophilia Hematopoietic 1.11 0.836 – 1.48 0.464 48 359 exclusion phecode
289 Other diseases of blood and blood-forming organs Hematopoietic 1.03 0.952 – 1.12 0.43 713 3255 exclusion phecode
289.3
Personal history of diseases of blood and
Personal history of diseases of blood and blood-forming organs
 Hematopoietic 1.09 0.967 – 1.23 0.157 358 1665 exclusion phecode
289.4 Lymphadenitis Hematopoietic 1.04 0.975 – 1.11 0.228 1100 6068 exclusion phecode
289.5 Diseases of spleen Hematopoietic 1.12 0.938 – 1.33 0.214 168 754 exclusion phecode
289.8 Polycythemia, secondary Hematopoietic 1.08 0.89 – 1.31 0.436 126 546 exclusion phecode
289.9 Abnormality of red blood cells Hematopoietic 0.996 0.85 – 1.17 0.961 181 808 exclusion phecode
290
Delirium dementia and amnestic and other
Delirium dementia and amnestic and other cognitive disorders
 Mental Disorders 1.08 0.984 – 1.19 0.106 554 2261 exclusion phecode
290.1 Dementias Mental Disorders 1.05 0.903 – 1.21 0.545 222 1011 exclusion phecode
290.11 Alzheimer's disease Mental Disorders 1.12 0.857 – 1.46 0.406 63 297 exclusion phecode
290.12 Dementia with cerebral degenerations Mental Disorders 1.11 0.807 – 1.54 0.509 46 162 exclusion phecode
290.13 Senile dementia Mental Disorders 0.961 0.801 – 1.15 0.669 145 620 exclusion phecode
290.16 Vascular dementia Mental Disorders 0.862 0.591 – 1.26 0.438 42 157 exclusion phecode
290.2 Delirium due to conditions classified elsewhere Mental Disorders 1.09 0.97 – 1.23 0.146 338 1417 exclusion phecode
290.3
Other persistent mental disorders due to
Other persistent mental disorders due to conditions classified elsewhere
 Mental Disorders 1.05 0.932 – 1.18 0.424 340 1787 exclusion phecode
291
Other specified nonpsychotic and/or transient
Other specified nonpsychotic and/or transient mental disorders
 Mental Disorders 1.01 0.946 – 1.09 0.683 991 4769 exclusion phecode
291.1
Transient mental disorders due to conditions
Transient mental disorders due to conditions classified elsewhere
 Mental Disorders 1.16 0.892 – 1.52 0.262 64 389 exclusion phecode
291.4
Specific nonpsychotic mental disorders due to
Specific nonpsychotic mental disorders due to brain damage
 Mental Disorders 0.986 0.837 – 1.16 0.862 173 924 exclusion phecode
291.8 Alteration of consciousness Mental Disorders 1.02 0.945 – 1.1 0.603 808 3871 exclusion phecode
292 Neurological disorders Mental Disorders 1.03 0.979 – 1.08 0.259 2012 6897 exclusion phecode
292.1 Aphasia/speech disturbance Mental Disorders 0.994 0.912 – 1.08 0.898 596 3623 exclusion phecode
292.11 Aphasia Mental Disorders 1.02 0.883 – 1.19 0.75 215 1193 exclusion phecode
292.12 Symbolic dysfunction Mental Disorders 0.965 0.717 – 1.3 0.814 50 354 exclusion phecode
292.2 Mild cognitive impairment Mental Disorders 1.07 0.906 – 1.26 0.428 188 757 exclusion phecode
292.3 Memory loss Mental Disorders 1.03 0.954 – 1.12 0.414 719 3457 exclusion phecode
292.4 Altered mental status Mental Disorders 1.04 0.967 – 1.11 0.315 1049 4350 exclusion phecode
292.5 Transient alteration of awareness Mental Disorders 1.05 0.896 – 1.23 0.536 184 887 exclusion phecode
292.6 Hallucinations Mental Disorders 0.826 0.661 – 1.03 0.0934 93 401 exclusion phecode
293 Symptoms involving head and neck Mental Disorders 0.951 0.791 – 1.14 0.595 135 861 exclusion phecode
293.1
Swelling, mass, or lump in head and neck
Swelling, mass, or lump in head and neck [Space-occupying lesion, intracranial NOS]
 Mental Disorders 1.03 0.965 – 1.1 0.387 1093 7651 exclusion phecode
295 Schizophrenia and other psychotic disorders Mental Disorders 1.02 0.905 – 1.15 0.721 371 1210 exclusion phecode
295.1 Schizophrenia Mental Disorders 1.15 0.779 – 1.7 0.482 38 211 exclusion phecode
295.2 Paranoid disorders Mental Disorders 0.946 0.658 – 1.36 0.763 46 155 exclusion phecode
295.3 Psychosis Mental Disorders 1.03 0.9 – 1.17 0.691 320 1037 exclusion phecode
296 Mood disorders Mental Disorders 1.03 0.976 – 1.08 0.317 4100 2877 exclusion phecode
296.1 Bipolar Mental Disorders 1.05 0.93 – 1.18 0.454 384 1539 exclusion phecode
296.2 Depression Mental Disorders 1.03 0.979 – 1.08 0.255 3956 2877 exclusion phecode
296.22 Major depressive disorder Mental Disorders 1.02 0.97 – 1.08 0.42 3663 2874 exclusion phecode
297 Suicidal ideation or attempt Mental Disorders 1.06 0.934 – 1.2 0.372 361 1257 exclusion phecode
297.1 Suicidal ideation Mental Disorders 1.07 0.933 – 1.24 0.32 289 1042 exclusion phecode
297.2 Suicide or self-inflicted injury Mental Disorders 1.19 0.942 – 1.51 0.143 104 364 exclusion phecode
300 Anxiety disorders Mental Disorders 1.03 0.98 – 1.08 0.238 4064 2877 exclusion phecode
300.1 Anxiety disorder Mental Disorders 1.03 0.976 – 1.08 0.3 3817 2880 exclusion phecode
300.11 Generalized anxiety disorder Mental Disorders 0.978 0.918 – 1.04 0.499 1751 2820 exclusion phecode
300.12 Agorophobia, social phobia, and panic disorder Mental Disorders 1.02 0.912 – 1.14 0.742 457 1569 exclusion phecode
300.13 Phobia Mental Disorders 0.949 0.836 – 1.08 0.416 344 1373 exclusion phecode
300.3 Obsessive-compulsive disorders Mental Disorders 0.917 0.743 – 1.13 0.422 110 509 exclusion phecode
300.4 Dysthymic disorder Mental Disorders 0.961 0.886 – 1.04 0.334 849 2320 exclusion phecode
300.8 Acute reaction to stress Mental Disorders 1.03 0.869 – 1.21 0.76 198 767 exclusion phecode
300.9 Posttraumatic stress disorder Mental Disorders 0.974 0.836 – 1.14 0.738 224 1086 exclusion phecode
301 Personality disorders Mental Disorders 1.1 0.908 – 1.33 0.33 153 656 exclusion phecode
301.2 Antisocial/borderline personality disorder Mental Disorders 1.16 0.879 – 1.52 0.299 77 352 exclusion phecode
302 Sexual and gender identity disorders Mental Disorders 1.02 0.95 – 1.1 0.571 1300 2056 exclusion phecode
302.1 Decreased libido Mental Disorders 0.858 0.724 – 1.02 0.077 183 781 exclusion phecode
303 Psychogenic and somatoform disorders Mental Disorders 1 0.945 – 1.06 0.973 2417 2780 exclusion phecode
303.1 Dissociative disorder Mental Disorders 0.842 0.595 – 1.19 0.333 42 246 exclusion phecode
303.3 Psychogenic disorder Mental Disorders 0.997 0.941 – 1.06 0.917 2332 2753 exclusion phecode
303.31
Gastrointestinal malfunction arising from
Gastrointestinal malfunction arising from mental factors
 Mental Disorders 0.901 0.752 – 1.08 0.259 152 713 exclusion phecode
303.4 Somatoform disorder Mental Disorders 0.992 0.874 – 1.13 0.905 308 1497 exclusion phecode
304 Adjustment reaction Mental Disorders 0.987 0.922 – 1.06 0.705 1351 2839 exclusion phecode
305.2 Eating disorder Mental Disorders 0.916 0.81 – 1.04 0.16 354 1266 exclusion phecode
306 Other mental disorder Mental Disorders 0.989 0.9 – 1.09 0.81 632 1995 exclusion phecode
306.1 Mental disorders durring/after pregnancy Mental Disorders 1.14 0.945 – 1.37 0.172 186 521 exclusion phecode
306.9 Tension headache Mental Disorders 0.924 0.801 – 1.07 0.279 254 1119 exclusion phecode
312 Conduct disorders Mental Disorders 0.898 0.719 – 1.12 0.342 98 469 exclusion phecode
312.3 Impulse control disorder Mental Disorders 0.66 0.429 – 1.02 0.0598 26 172 exclusion phecode
313 Pervasive developmental disorders Mental Disorders 0.925 0.834 – 1.03 0.141 437 2805 exclusion phecode
313.1 Attention deficit hyperactivity disorder Mental Disorders 0.918 0.822 – 1.03 0.13 378 2488 exclusion phecode
313.2 Tics and stuttering Mental Disorders 0.772 0.49 – 1.22 0.265 26 122 exclusion phecode
313.3 Autism Mental Disorders 0.859 0.532 – 1.39 0.535 23 106 exclusion phecode
315 Develomental delays and disorders Mental Disorders 1.07 0.941 – 1.22 0.293 269 1348 exclusion phecode
315.1 Learning disorder Mental Disorders 0.875 0.598 – 1.28 0.492 37 171 exclusion phecode
315.2 Speech and language disorder Mental Disorders 1.1 0.871 – 1.38 0.43 82 448 exclusion phecode
316 Substance addiction and disorders Mental Disorders 1.06 0.987 – 1.13 0.111 1043 5713 exclusion phecode
316.1 Polyneuropathy due to drugs Mental Disorders 1.11 0.932 – 1.32 0.24 141 1014 exclusion phecode
317 Alcohol-related disorders Mental Disorders 1.04 0.963 – 1.12 0.314 767 4157 exclusion phecode
317.1 Alcoholism Mental Disorders 1.03 0.944 – 1.12 0.538 638 3533 exclusion phecode
317.11 Alcoholic liver damage Mental Disorders 0.991 0.836 – 1.18 0.922 172 772 exclusion phecode
318 Tobacco use disorder Mental Disorders 1.04 0.995 – 1.1 0.0757 2393 6376 exclusion phecode
320 Meningitis Neurological 1.09 0.885 – 1.34 0.423 103 723 exclusion phecode
323 Encephalitis Neurological 0.859 0.653 – 1.13 0.278 57 377 exclusion phecode
323.8 Encephalitis, non-infectious Neurological 0.893 0.676 – 1.18 0.427 51 307 exclusion phecode
324 Other CNS infection and poliomyelitis Neurological 0.995 0.776 – 1.28 0.969 73 594 exclusion phecode
325
Phlebitis and thrombophlebitis of intracranial
Phlebitis and thrombophlebitis of intracranial venous sinuses
 Neurological 0.766 0.469 – 1.25 0.287 16 120 exclusion phecode
327 Sleep disorders Neurological 0.999 0.959 – 1.04 0.968 4707 4911 exclusion phecode
327.1 Hypersomnia Neurological 1 0.928 – 1.08 0.954 836 3183 exclusion phecode
327.3 Sleep apnea Neurological 1.01 0.968 – 1.06 0.592 3462 4848 exclusion phecode
327.31 Central/nonobstroctive sleep apnea Neurological 1.02 0.883 – 1.18 0.767 222 927 exclusion phecode
327.32 Obstructive sleep apnea Neurological 1 0.958 – 1.05 0.874 3078 4752 exclusion phecode
327.4 Insomnia Neurological 0.972 0.923 – 1.02 0.297 2090 4805 exclusion phecode
327.41 Organic or persistent insomnia Neurological 0.894 0.81 – 0.986 0.0253 529 2041 exclusion phecode
327.5 Parasomnia Neurological 1.01 0.879 – 1.15 0.921 265 1049 exclusion phecode
327.6 Circadian rhythm sleep disorder Neurological 0.894 0.732 – 1.09 0.276 127 547 exclusion phecode
327.7 Sleep related movement disorders Neurological 0.922 0.846 – 1 0.0646 644 2781 exclusion phecode
327.71 Restless legs syndrome Neurological 0.906 0.825 – 0.994 0.0378 550 2452 exclusion phecode
327.72 Sleep related leg cramps Neurological 1.18 0.78 – 1.77 0.439 38 143 exclusion phecode
331 Other cerebral degenerations Neurological 1.05 0.917 – 1.21 0.46 244 1390 exclusion phecode
331.1 Hydrocephalus Neurological 1.15 0.849 – 1.56 0.367 45 465 exclusion phecode
331.9 Cerebral degeneration, unspecified Neurological 0.971 0.825 – 1.14 0.725 196 855 exclusion phecode
332 Parkinson's disease Neurological 0.848 0.702 – 1.02 0.0856 137 829 exclusion phecode
333
Extrapyramidal disease and abnormal movement
Extrapyramidal disease and abnormal movement disorders
 Neurological 0.937 0.874 – 1 0.0638 989 5040 exclusion phecode
333.1 Essential tremor Neurological 0.921 0.811 – 1.05 0.203 276 1451 exclusion phecode
333.2 Myoclonus Neurological 1.21 0.926 – 1.59 0.162 69 299 exclusion phecode
333.4 Torsion dystonia Neurological 1.06 0.851 – 1.32 0.597 96 615 exclusion phecode
333.8 Other degenerative diseases of the basal ganglia Neurological 1.19 0.824 – 1.72 0.352 44 201 exclusion phecode
334 Degenerative disease of the spinal cord Neurological 0.934 0.82 – 1.06 0.304 260 1858 exclusion phecode
334.1 Spinocerebellar disease Neurological 0.766 0.526 – 1.12 0.164 34 161 exclusion phecode
334.2 Anterior horn cell disease Neurological 0.668 0.445 – 1 0.0505 26 223 exclusion phecode
334.21 Amyotrophic Lateral Sclerosis Neurological 0.698 0.433 – 1.12 0.139 20 135 exclusion phecode
335 Multiple sclerosis Neurological 0.907 0.735 – 1.12 0.359 98 674 exclusion phecode
337 Disorders of the autonomic nervous system Neurological 1.02 0.909 – 1.14 0.755 358 1845 exclusion phecode
337.1 Peripheral autonomic neuropathy Neurological 1.01 0.874 – 1.16 0.94 248 1126 exclusion phecode
338 Pain Neurological 0.995 0.955 – 1.04 0.83 5169 4494 exclusion phecode
338.1 Acute pain Neurological 1 0.96 – 1.05 0.855 3716 4460 exclusion phecode
338.2 Chronic pain Neurological 0.994 0.949 – 1.04 0.794 3366 4466 exclusion phecode
339 Other headache syndromes Neurological 0.98 0.935 – 1.03 0.411 2691 6364 exclusion phecode
340 Migraine Neurological 0.935 0.885 – 0.989 0.0187 1799 5505 exclusion phecode
340.1 Migrain with aura Neurological 0.973 0.906 – 1.04 0.441 1019 4148 exclusion phecode
341
Other demyelinating diseases of central nervous
Other demyelinating diseases of central nervous system
 Neurological 0.972 0.703 – 1.34 0.862 45 254 exclusion phecode
342 Hemiplegia Neurological 0.97 0.827 – 1.14 0.711 177 875 exclusion phecode
343 Infantile cerebral palsy Neurological 1.23 0.75 – 2.03 0.407 19 136 exclusion phecode
344 Other paralytic syndromes Neurological 1.01 0.869 – 1.18 0.887 200 1132 exclusion phecode
345 Epilepsy, recurrent seizures, convulsions Neurological 0.997 0.92 – 1.08 0.951 669 4596 exclusion phecode
345.1 Epilepsy Neurological 1.03 0.893 – 1.19 0.687 209 1332 exclusion phecode
345.11 Generalized convulsive epilepsy Neurological 0.954 0.739 – 1.23 0.721 60 399 exclusion phecode
345.12 Partial epilepsy Neurological 0.962 0.812 – 1.14 0.657 145 946 exclusion phecode
345.3 Convulsions Neurological 0.986 0.907 – 1.07 0.74 637 4339 exclusion phecode
346
Abnormal findings on study of brain and/or
Abnormal findings on study of brain and/or nervous system
 Neurological 0.751 0.556 – 1.01 0.0612 54 332 exclusion phecode
346.1
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of skull and head
 Neurological 0.985 0.893 – 1.09 0.757 467 2767 exclusion phecode
346.2
Nonspecific abnormal results of function study
Nonspecific abnormal results of function study of brain and central nervous system
 Neurological 0.734 0.503 – 1.07 0.109 38 210 exclusion phecode
346.3
Nonspecific abnormal findings in cerebrospinal
Nonspecific abnormal findings in cerebrospinal fluid
 Neurological 0.696 0.47 – 1.03 0.0696 29 186 exclusion phecode
347 Cataplexy and narcolepsy Neurological 1.1 0.739 – 1.64 0.636 25 213 exclusion phecode
348 Other conditions of brain Neurological 0.977 0.891 – 1.07 0.618 530 3263 exclusion phecode
348.2 Cerebral edema and compression of brain Neurological 0.998 0.852 – 1.17 0.976 169 1532 exclusion phecode
348.4 Cerebral cysts Neurological 0.799 0.593 – 1.07 0.138 49 416 exclusion phecode
348.7 Coma Neurological 1.2 0.936 – 1.53 0.151 79 449 exclusion phecode
348.8 Encephalopathy, not elsewhere classified Neurological 1.03 0.915 – 1.15 0.644 349 1621 exclusion phecode
348.9 Other conditions of brain, NOS Neurological 1.07 0.982 – 1.16 0.121 610 4145 exclusion phecode
349
Other and unspecified disorders of the nervous
Other and unspecified disorders of the nervous system
 Neurological 0.968 0.85 – 1.1 0.618 275 1634 exclusion phecode
350 Abnormal movement Neurological 1.01 0.962 – 1.06 0.68 2326 6954 exclusion phecode
350.1 Abnormal involuntary movements Neurological 0.988 0.927 – 1.05 0.705 1167 5629 exclusion phecode
350.2 Abnormality of gait Neurological 0.99 0.933 – 1.05 0.736 1460 5510 exclusion phecode
350.3 Lack of coordination Neurological 1.06 0.947 – 1.19 0.3 373 1959 exclusion phecode
350.5 Abnormal reflex Neurological 1.11 0.85 – 1.45 0.441 66 360 exclusion phecode
350.6 Disturbances of sensation of smell and taste Neurological 1.03 0.864 – 1.23 0.745 134 1038 exclusion phecode
351 Other peripheral nerve disorders Neurological 0.912 0.869 – 0.957 0.000161 2515 6009 exclusion phecode
352 Disorders of other cranial nerves Neurological 0.933 0.833 – 1.04 0.229 346 2885 exclusion phecode
352.1 Trigeminal nerve disorders [CN5] Neurological 0.822 0.68 – 0.993 0.0426 131 850 exclusion phecode
352.2 Facial nerve disorders [CN7] Neurological 0.934 0.8 – 1.09 0.388 181 1334 exclusion phecode
353 Nerve root and plexus disorders Neurological 0.942 0.887 – 1 0.0524 1337 5759 exclusion phecode
353.1 Nerve plexus lesions Neurological 0.947 0.75 – 1.2 0.648 89 686 exclusion phecode
353.2 Nerve root lesions Neurological 0.965 0.685 – 1.36 0.838 37 250 exclusion phecode
355 Complex regional/central pain syndrome Neurological 0.969 0.809 – 1.16 0.735 139 904 exclusion phecode
355.1 Chronic pain syndrome Neurological 0.964 0.847 – 1.1 0.583 291 1467 exclusion phecode
356 Hereditary and idiopathic peripheral neuropathy Neurological 0.981 0.915 – 1.05 0.579 1010 4136 exclusion phecode
357 Inflammatory and toxic neuropathy Neurological 0.994 0.936 – 1.06 0.856 1360 5669 exclusion phecode
358 Myoneural disorders Neurological 1.02 0.914 – 1.13 0.74 387 2283 exclusion phecode
358.1 Myasthenia gravis Neurological 0.932 0.563 – 1.54 0.782 23 197 exclusion phecode
359 Muscular dystrophies and other myopathies Neurological 0.975 0.876 – 1.08 0.64 378 2177 exclusion phecode
359.1 Muscular dystrophies Neurological 0.567 0.319 – 1.01 0.0533 13 122 exclusion phecode
359.2 Myopathy Neurological 0.974 0.875 – 1.08 0.633 370 2102 exclusion phecode
360 Disorders of the globe Sense Organs 0.844 0.644 – 1.11 0.217 62 306 exclusion phecode
360.2 Progressive myopia Sense Organs 0.956 0.659 – 1.39 0.811 32 141 exclusion phecode
361 Retinal detachments and defects Sense Organs 0.831 0.732 – 0.944 0.00444 295 1588 exclusion phecode
361.1 Retinal detachment with retinal defect Sense Organs 0.842 0.694 – 1.02 0.0824 120 662 exclusion phecode
362 Other retinal disorders Sense Organs 0.961 0.906 – 1.02 0.189 1607 4119 exclusion phecode
362.2
Degeneration of macula and posterior pole of
Degeneration of macula and posterior pole of retina
 Sense Organs 0.983 0.911 – 1.06 0.649 941 2928 exclusion phecode
362.21 Macular degeneration, dry Sense Organs 0.896 0.761 – 1.05 0.186 193 676 exclusion phecode
362.22 Macular degeneration, wet Sense Organs 0.867 0.659 – 1.14 0.309 63 275 exclusion phecode
362.23 Cystoid macular degeneration of retina Sense Organs 1.03 0.876 – 1.22 0.688 180 807 exclusion phecode
362.26 Macular puckering of retina Sense Organs 1 0.906 – 1.11 0.956 453 1856 exclusion phecode
362.27 Drusen (degenerative) of retina Sense Organs 0.887 0.765 – 1.03 0.112 217 972 exclusion phecode
362.29 Macular degeneration (senile) of retina NOS Sense Organs 0.969 0.895 – 1.05 0.448 814 2690 exclusion phecode
362.3 Other nondiabetic retinopathy Sense Organs 0.913 0.829 – 1.01 0.0639 508 1857 exclusion phecode
362.31 Separation of retinal layers Sense Organs 0.86 0.724 – 1.02 0.084 157 925 exclusion phecode
362.4 Retinal vascular changes and abnomalities Sense Organs 0.905 0.803 – 1.02 0.0991 320 1339 exclusion phecode
362.6 Peripheral retinal degenerations Sense Organs 0.98 0.833 – 1.15 0.811 170 843 exclusion phecode
362.7 Hereditary retinal dystrophies Sense Organs 1.05 0.825 – 1.32 0.713 88 453 exclusion phecode
362.8 Retinal hemorrhage/ischemia Sense Organs 0.896 0.729 – 1.1 0.301 103 640 exclusion phecode
362.9 Retinal edema Sense Organs 0.956 0.81 – 1.13 0.588 177 780 exclusion phecode
363
Chorioretinal inflammations, scars, and other
Chorioretinal inflammations, scars, and other disorders of choroid
 Sense Organs 0.863 0.738 – 1.01 0.0655 190 1001 exclusion phecode
363.3 Chorioretinal scars Sense Organs 0.826 0.69 – 0.989 0.0371 138 698 exclusion phecode
364 Corneal opacity and other disorders of cornea Sense Organs 0.939 0.845 – 1.04 0.245 419 2214 exclusion phecode
364.1 Corneal opacity Sense Organs 0.837 0.703 – 0.995 0.044 151 858 exclusion phecode
364.2 Corneal edema Sense Organs 0.839 0.613 – 1.15 0.274 55 284 exclusion phecode
364.4 Corneal degenerations Sense Organs 0.83 0.695 – 0.993 0.0415 148 903 exclusion phecode
364.41 Keratoconus Sense Organs 0.875 0.593 – 1.29 0.499 29 178 exclusion phecode
364.5 Corneal dystrophy Sense Organs 1.05 0.894 – 1.23 0.567 188 967 exclusion phecode
364.51 Fuchs' dystrophy Sense Organs 0.967 0.772 – 1.21 0.772 92 560 exclusion phecode
364.9 Cornea replaced by transplant Sense Organs 0.986 0.66 – 1.47 0.947 33 198 exclusion phecode
365 Glaucoma Sense Organs 0.938 0.875 – 1.01 0.0736 1000 4103 exclusion phecode
365.1 Open-angle glaucoma Sense Organs 0.933 0.825 – 1.05 0.267 313 1412 exclusion phecode
365.11 Primary open angle glaucoma Sense Organs 0.967 0.823 – 1.14 0.687 177 848 exclusion phecode
365.2 Primary angle-closure glaucoma Sense Organs 0.976 0.793 – 1.2 0.819 107 546 exclusion phecode
366 Cataract Sense Organs 1.03 0.979 – 1.08 0.267 3355 4691 exclusion phecode
366.1 Nonsenile Cataract Sense Organs 1.06 0.846 – 1.34 0.603 88 388 exclusion phecode
366.2 Senile cataract Sense Organs 1.02 0.967 – 1.08 0.467 2468 4156 exclusion phecode
367
Disorders of refraction and accommodation
Disorders of refraction and accommodation; blindness and low vision
 Sense Organs 0.969 0.929 – 1.01 0.146 3640 6032 exclusion phecode
367.1 Myopia Sense Organs 0.966 0.918 – 1.02 0.197 2059 5613 exclusion phecode
367.2 Astigmatism Sense Organs 0.977 0.925 – 1.03 0.421 1691 5352 exclusion phecode
367.8 Hypermetropia Sense Organs 0.939 0.868 – 1.02 0.118 784 3254 exclusion phecode
367.9 Blindness and low vision Sense Organs 0.954 0.863 – 1.05 0.357 495 2209 exclusion phecode
368 Visual disturbances Sense Organs 1.04 0.987 – 1.09 0.144 2006 7405 exclusion phecode
368.1 Amblyopia Sense Organs 1.15 0.99 – 1.34 0.0681 217 1410 exclusion phecode
368.2 Diplopia and disorders of binocular vision Sense Organs 1.01 0.908 – 1.13 0.797 386 2220 exclusion phecode
368.3 Anisometropia Sense Organs 0.931 0.745 – 1.16 0.534 87 471 exclusion phecode
368.4 Visual field defects Sense Organs 0.976 0.88 – 1.08 0.639 432 2219 exclusion phecode
368.9 Subjective visual disturbances Sense Organs 0.916 0.82 – 1.02 0.117 403 2198 exclusion phecode
368.91 Psychophysical visual disturbances Sense Organs 0.767 0.551 – 1.07 0.117 51 228 exclusion phecode
369 Infection of the eye Sense Organs 0.945 0.887 – 1.01 0.0805 1240 4946 exclusion phecode
369.2 Eye infection, viral Sense Organs 1.03 0.876 – 1.22 0.702 178 990 exclusion phecode
369.5 Conjunctivitis, infectious Sense Organs 0.947 0.885 – 1.01 0.11 1082 4509 exclusion phecode
370 Keratitis Sense Organs 0.998 0.908 – 1.1 0.961 517 2507 exclusion phecode
370.1 Corneal ulcer Sense Organs 1.04 0.825 – 1.32 0.726 84 500 exclusion phecode
370.2 Superficial keratitis Sense Organs 0.916 0.789 – 1.06 0.251 213 1020 exclusion phecode
370.3 Keratoconjunctivitis Sense Organs 0.966 0.84 – 1.11 0.628 241 1169 exclusion phecode
370.31 Keratoconjunctivitis sicca Sense Organs 1.03 0.799 – 1.32 0.834 79 304 exclusion phecode
371 Inflammation of the eye Sense Organs 0.97 0.919 – 1.02 0.28 1779 5798 exclusion phecode
371.1 Uveitis, noninfectious or NOS Sense Organs 0.905 0.779 – 1.05 0.187 210 1129 exclusion phecode
371.2 Conjunctivitis, noninfectious Sense Organs 0.944 0.842 – 1.06 0.323 355 1858 exclusion phecode
371.21 Allergic conjunctivitis Sense Organs 0.93 0.821 – 1.05 0.252 302 1566 exclusion phecode
371.3 Inflammation of eyelids Sense Organs 0.968 0.911 – 1.03 0.295 1399 4897 exclusion phecode
371.33 Noninfectious dermatoses of eyelid Sense Organs 0.964 0.716 – 1.3 0.809 47 247 exclusion phecode
372 Disorders of conjunctiva Sense Organs 1.08 0.973 – 1.21 0.146 420 2128 exclusion phecode
374 Other disorders of eyelids Sense Organs 1.01 0.942 – 1.08 0.837 1102 4337 exclusion phecode
374.1 Ectropion or entropion Sense Organs 0.961 0.81 – 1.14 0.644 142 758 exclusion phecode
374.2 Lagophthalmos Sense Organs 0.942 0.693 – 1.28 0.701 46 369 exclusion phecode
374.3 Ptosis of eyelid Sense Organs 0.987 0.888 – 1.1 0.812 404 1973 exclusion phecode
374.6 Dermatochalasis Sense Organs 1 0.901 – 1.11 0.984 430 1859 exclusion phecode
375 Disorders of lacrimal system Sense Organs 0.934 0.88 – 0.992 0.0268 1517 4633 exclusion phecode
375.1 Dry eyes Sense Organs 0.947 0.894 – 1 0.0672 1672 4750 exclusion phecode
375.2 Epiphora Sense Organs 0.911 0.768 – 1.08 0.29 167 816 exclusion phecode
376 Disorders of the orbit Sense Organs 0.96 0.751 – 1.23 0.744 77 591 exclusion phecode
377 Disorders of optic nerve and visual pathways Sense Organs 1.02 0.898 – 1.15 0.777 296 1648 exclusion phecode
377.1 Optic atrophy Sense Organs 0.896 0.739 – 1.08 0.26 123 616 exclusion phecode
377.3 Optic neuritis/neuropathy Sense Organs 1.08 0.916 – 1.26 0.375 174 1003 exclusion phecode
378
Strabismus and other disorders of binocular eye
Strabismus and other disorders of binocular eye movements
 Sense Organs 1.08 0.971 – 1.19 0.162 423 2264 exclusion phecode
378.1 Strabismus (not specified as paralytic) Sense Organs 1.03 0.911 – 1.17 0.623 289 1521 exclusion phecode
378.2 Nystagmus and other irregular eye movements Sense Organs 1.06 0.797 – 1.42 0.681 54 303 exclusion phecode
378.5 Paralytic strabismus Sense Organs 1.13 0.91 – 1.41 0.267 96 594 exclusion phecode
379 Other disorders of eye Sense Organs 0.975 0.925 – 1.03 0.345 2101 5291 exclusion phecode
379.1 Scleritis and episcleritis Sense Organs 1.03 0.776 – 1.38 0.821 66 348 exclusion phecode
379.2 Disorders of vitreous body Sense Organs 0.974 0.918 – 1.03 0.391 1562 4216 exclusion phecode
379.3 Aphakia and other disorders of lens Sense Organs 0.81 0.617 – 1.07 0.132 65 299 exclusion phecode
379.4 Anomalies of pupillary function Sense Organs 0.939 0.754 – 1.17 0.575 106 595 exclusion phecode
379.5 Disorders of iris and ciliary body Sense Organs 0.904 0.731 – 1.12 0.349 115 651 exclusion phecode
379.51 Pigmentary iris degeneration Sense Organs 0.834 0.49 – 1.42 0.503 22 111 exclusion phecode
379.9 Pain, swelling or discharge of eye Sense Organs 0.893 0.801 – 0.995 0.041 404 1996 exclusion phecode
380 Disorders of external ear Sense Organs 1.01 0.943 – 1.09 0.739 981 4293 exclusion phecode
380.1 Otitis externa Sense Organs 0.985 0.9 – 1.08 0.749 578 3124 exclusion phecode
380.4 Impacted cerumen Sense Organs 1.04 0.972 – 1.11 0.269 1172 4895 exclusion phecode
381 Otitis media and Eustachian tube disorders Sense Organs 0.955 0.901 – 1.01 0.122 1408 6837 exclusion phecode
381.1 Otitis media Sense Organs 0.97 0.906 – 1.04 0.378 995 5630 exclusion phecode
381.11 Suppurative and unspecified otitis media Sense Organs 0.976 0.906 – 1.05 0.532 840 4876 exclusion phecode
381.2 Eustachian tube disorders Sense Organs 0.935 0.86 – 1.02 0.12 665 3656 exclusion phecode
381.3 Mastoiditis & related conditions Sense Organs 0.888 0.636 – 1.24 0.483 36 299 exclusion phecode
381.9 Otorrhea Sense Organs 0.949 0.756 – 1.19 0.65 92 686 exclusion phecode
382 Otalgia Sense Organs 0.993 0.913 – 1.08 0.875 668 3697 exclusion phecode
383 Otosclerosis Sense Organs 1.06 0.664 – 1.69 0.809 19 221 exclusion phecode
384 Other disorders of tympanic membrane Sense Organs 1.01 0.842 – 1.21 0.91 133 932 exclusion phecode
384.1 Myringitis Sense Organs 0.805 0.469 – 1.38 0.431 14 102 exclusion phecode
384.4 Perforation of tympanic membrane Sense Organs 1.05 0.852 – 1.3 0.636 99 727 exclusion phecode
385 Other disorders of middle ear and mastoid Sense Organs 1.16 0.931 – 1.45 0.185 87 749 exclusion phecode
385.3 Cholesteatoma Sense Organs 1.12 0.824 – 1.53 0.463 41 449 exclusion phecode
385.5
Tympanosclerosis and middle ear disease related
Tympanosclerosis and middle ear disease related to otitis media
 Sense Organs 0.775 0.51 – 1.18 0.234 25 208 exclusion phecode
386
Vertiginous syndromes and other disorders of
Vertiginous syndromes and other disorders of vestibular system
 Sense Organs 1.02 0.939 – 1.11 0.645 695 3334 exclusion phecode
386.1 Meniere's disease Sense Organs 1.19 0.958 – 1.49 0.115 93 608 exclusion phecode
386.2 Peripheral or central vertigo Sense Organs 1.05 0.958 – 1.14 0.306 603 2850 exclusion phecode
386.21 Central origin vertigo Sense Organs 1.07 0.961 – 1.18 0.23 453 2198 exclusion phecode
386.3 Labyrinthitis Sense Organs 1.05 0.955 – 1.15 0.317 540 2695 exclusion phecode
386.9
Dizziness and giddiness (Light-headedness and
Dizziness and giddiness (Light-headedness and vertigo)
 Sense Organs 1.03 0.987 – 1.08 0.161 2621 6767 exclusion phecode
388 Other disorders of ear Sense Organs 0.995 0.882 – 1.12 0.932 317 1867 exclusion phecode
389 Hearing loss Sense Organs 1.04 0.987 – 1.09 0.152 2596 6848 exclusion phecode
389.1 Sensorineural hearing loss Sense Organs 1 0.944 – 1.06 0.936 1458 5314 exclusion phecode
389.2 Conductive hearing loss Sense Organs 0.983 0.855 – 1.13 0.806 238 1661 exclusion phecode
389.3 Degenerative and vascular disorders of ear Sense Organs 0.799 0.621 – 1.03 0.0812 87 385 exclusion phecode
389.4 Tinnitus Sense Organs 1.01 0.934 – 1.09 0.805 755 4233 exclusion phecode
389.5 Disorders of acoustic nerve Sense Organs 1.11 0.78 – 1.58 0.562 38 203 exclusion phecode
394 Rheumatic disease of the heart valves Circulatory System 1.04 0.959 – 1.13 0.344 818 2497 exclusion phecode
394.1 Mitral valve stenosis and aortic valve stenosis Circulatory System 1.09 0.934 – 1.27 0.273 223 686 exclusion phecode
394.2 Mitral valve disease Circulatory System 1.01 0.877 – 1.16 0.906 253 833 exclusion phecode
394.3 Aortic valve disease Circulatory System 1.06 0.862 – 1.3 0.579 118 313 exclusion phecode
394.4 Acute rheumatic heart disease Circulatory System 0.539 0.331 – 0.877 0.0129 28 84 exclusion phecode
394.7 Disease of tricuspid valve Circulatory System 1.02 0.901 – 1.16 0.716 342 992 exclusion phecode
395 Heart valve disorders Circulatory System 1.1 1.04 – 1.16 0.000684 1781 5007 exclusion phecode
395.1 Nonrheumatic mitral valve disorders Circulatory System 1.08 1.01 – 1.16 0.0341 944 3695 exclusion phecode
395.2 Nonrheumatic aortic valve disorders Circulatory System 1.13 1.05 – 1.21 0.00083 1106 3153 exclusion phecode
395.3 Nonrheumatic tricuspid valve disorders Circulatory System 1.09 0.954 – 1.26 0.196 271 916 exclusion phecode
395.4 Nonrheumatic pulmonary valve disorders Circulatory System 0.976 0.697 – 1.37 0.886 49 220 exclusion phecode
395.6 Heart valve replaced Circulatory System 1.06 0.971 – 1.16 0.188 632 1913 exclusion phecode
396 Abnormal heart sounds Circulatory System 1.07 1.01 – 1.13 0.0162 1701 6102 exclusion phecode
401 Hypertension Circulatory System 1.06 1.01 – 1.11 0.0284 6218 3441 exclusion phecode
401.1 Essential hypertension Circulatory System 1.06 1 – 1.11 0.0336 6184 3441 exclusion phecode
401.2 Hypertensive heart and/or renal disease Circulatory System 1.18 1.1 – 1.27 6.83e-06 1824 1963 exclusion phecode
401.21 Hypertensive heart disease Circulatory System 1.2 1.08 – 1.35 0.00127 503 865 exclusion phecode
401.22 Hypertensive chronic kidney disease Circulatory System 1.14 1.06 – 1.24 0.000837 1331 1724 exclusion phecode
401.3 Other hypertensive complications Circulatory System 1.14 1.06 – 1.23 0.000392 1319 2190 exclusion phecode
411 Ischemic Heart Disease Circulatory System 1.18 1.12 – 1.24 6.35e-11 3542 4571 exclusion phecode
411.1 Unstable angina (intermediate coronary syndrome) Circulatory System 1.18 1.07 – 1.3 0.00111 623 1458 exclusion phecode
411.2 Myocardial infarction Circulatory System 1.19 1.11 – 1.27 3.61e-07 1481 3181 exclusion phecode
411.3 Angina pectoris Circulatory System 1.17 1.1 – 1.26 3.27e-06 1377 2730 exclusion phecode
411.4 Coronary atherosclerosis Circulatory System 1.18 1.12 – 1.25 1.38e-10 3191 4127 exclusion phecode
411.41 Aneurysm and dissection of heart Circulatory System 1.38 1.07 – 1.79 0.0148 103 261 exclusion phecode
411.8
Other chronic ischemic heart disease
Other chronic ischemic heart disease, unspecified
 Circulatory System 1.2 1.14 – 1.27 1.93e-11 2730 3819 exclusion phecode
411.9
Other acute and subacute forms of ischemic
Other acute and subacute forms of ischemic heart disease
 Circulatory System 1.21 1.04 – 1.39 0.0119 270 766 exclusion phecode
414 Other forms of chronic heart disease Circulatory System 1.22 1.15 – 1.3 2.44e-10 1601 3367 exclusion phecode
414.2 ASCVD Circulatory System 1.15 1.02 – 1.29 0.0199 428 1190 exclusion phecode
415 Pulmonary heart disease Circulatory System 1.08 1.02 – 1.15 0.0135 1283 5664 exclusion phecode
415.1 Acute pulmonary heart disease Circulatory System 1.07 0.985 – 1.17 0.104 598 3595 exclusion phecode
415.11 Pulmonary embolism and infarction, acute Circulatory System 1.08 0.988 – 1.17 0.0937 594 3582 exclusion phecode
415.2 Chronic pulmonary heart disease Circulatory System 1.11 1.03 – 1.2 0.00531 884 3616 exclusion phecode
415.21 Primary pulmonary hypertension Circulatory System 1.07 0.953 – 1.21 0.242 370 1449 exclusion phecode
416 Cardiomegaly Circulatory System 0.962 0.881 – 1.05 0.385 635 2573 exclusion phecode
418 Nonspecific chest pain Circulatory System 1.05 1 – 1.09 0.0314 4841 4792 exclusion phecode
418.1 Precordial pain Circulatory System 1.07 0.981 – 1.17 0.126 699 2093 exclusion phecode
420 Carditis Circulatory System 1.03 0.954 – 1.12 0.408 742 3111 exclusion phecode
420.1 Myocarditis Circulatory System 0.979 0.724 – 1.32 0.89 49 193 exclusion phecode
420.2 Pericarditis Circulatory System 1.02 0.909 – 1.14 0.778 376 1611 exclusion phecode
420.21 Acute pericarditis Circulatory System 1.08 0.842 – 1.39 0.534 86 315 exclusion phecode
420.22 Chronic pericarditis Circulatory System 1.03 0.748 – 1.42 0.847 61 205 exclusion phecode
420.3 Endocarditis Circulatory System 1.02 0.911 – 1.14 0.75 388 1542 exclusion phecode
425 Cardiomyopathy Circulatory System 1.13 1.06 – 1.21 0.000444 1064 3986 exclusion phecode
425.1 Primary/intrinsic cardiomyopathies Circulatory System 1.11 1.04 – 1.19 0.00232 1032 3842 exclusion phecode
425.11 Hypertrophic obstructive cardiomyopathy Circulatory System 1.04 0.841 – 1.29 0.708 103 429 exclusion phecode
425.12 Other hypertrophic cardiomyopathy Circulatory System 1.28 0.997 – 1.64 0.0529 81 364 exclusion phecode
425.2 Secondary/extrinsic cardiomyopathies Circulatory System 1.04 0.884 – 1.23 0.622 166 675 exclusion phecode
425.8 Other cardiomyopathy Circulatory System 0.917 0.646 – 1.3 0.626 46 159 exclusion phecode
426 Cardiac conduction disorders Circulatory System 1.09 1.03 – 1.15 0.00129 4609 3177 exclusion phecode
426.2 Atrioventricular [AV] block Circulatory System 1.06 0.965 – 1.16 0.237 947 1279 exclusion phecode
426.21 First degree AV block Circulatory System 1.05 0.944 – 1.16 0.376 655 984 exclusion phecode
426.22 Mobitz II AV block Circulatory System 0.97 0.645 – 1.46 0.885 38 75 exclusion phecode
426.23 Second degree AV block Circulatory System 1.14 0.908 – 1.42 0.264 122 254 exclusion phecode
426.24 Atrioventricular block, complete Circulatory System 1.11 0.944 – 1.3 0.207 265 449 exclusion phecode
426.25 Other heart block Circulatory System 1.07 0.816 – 1.4 0.629 108 214 exclusion phecode
426.3 Bundle branch block Circulatory System 1.09 1.01 – 1.19 0.0355 1025 1573 exclusion phecode
426.31 Right bundle branch block Circulatory System 1.09 0.983 – 1.2 0.106 615 1207 exclusion phecode
426.32 Left bundle branch block Circulatory System 1.06 0.948 – 1.19 0.3 483 945 exclusion phecode
426.4 Anomalous atrioventricular excitation Circulatory System 0.817 0.455 – 1.46 0.497 20 80 exclusion phecode
426.7 Abnormal electrocardiogram [ECG] [EKG] Circulatory System 1.09 1.04 – 1.15 0.000929 4182 3155 exclusion phecode
426.8 Other cardiac conduction disorders Circulatory System 1.13 0.989 – 1.28 0.0727 334 857 exclusion phecode
426.9 Cardiac pacemaker/device in situ Circulatory System 1.12 1.02 – 1.23 0.0139 799 1301 exclusion phecode
426.91 Cardiac pacemaker in situ Circulatory System 1.1 0.979 – 1.23 0.111 527 914 exclusion phecode
426.92 Cardiac defibrillator in situ Circulatory System 1.17 1.04 – 1.31 0.0105 468 847 exclusion phecode
427 Cardiac dysrhythmias Circulatory System 1.09 1.04 – 1.14 0.000734 5493 3254 exclusion phecode
427.1 Paroxysmal tachycardia, unspecified Circulatory System 1.11 1.03 – 1.21 0.00887 1058 2099 exclusion phecode
427.11 Paroxysmal supraventricular tachycardia Circulatory System 1.1 0.998 – 1.22 0.0545 601 1627 exclusion phecode
427.12 Paroxysmal ventricular tachycardia Circulatory System 1.14 1.03 – 1.27 0.0126 624 1182 exclusion phecode
427.2 Atrial fibrillation and flutter Circulatory System 1.11 1.03 – 1.19 0.00371 2013 2138 exclusion phecode
427.21 Atrial fibrillation Circulatory System 1.11 1.03 – 1.19 0.00573 1972 2090 exclusion phecode
427.22 Atrial flutter Circulatory System 1.08 0.976 – 1.19 0.139 764 1206 exclusion phecode
427.3 Other specified cardiac dysrhythmias Circulatory System 1.11 1.04 – 1.17 0.000501 3224 3171 exclusion phecode
427.4 Cardiac arrest and ventricular fibrillation Circulatory System 1.09 0.944 – 1.27 0.236 270 627 exclusion phecode
427.41 Ventricular fibrillation and flutter Circulatory System 1.24 0.974 – 1.59 0.0808 125 292 exclusion phecode
427.42 Cardiac arrest Circulatory System 1.1 0.936 – 1.3 0.245 204 501 exclusion phecode
427.5 Arrhythmia (cardiac) NOS Circulatory System 1.07 1.01 – 1.14 0.0223 2442 3146 exclusion phecode
427.6 Premature beats Circulatory System 1.09 1.01 – 1.18 0.0371 1033 1948 exclusion phecode
427.61 Supraventricular premature beats Circulatory System 1.08 0.939 – 1.24 0.281 309 774 exclusion phecode
427.7 Tachycardia NOS Circulatory System 1.11 1.05 – 1.18 0.000752 1836 3185 exclusion phecode
427.8 Sinoatrial node dysfunction (Bradycardia) Circulatory System 1.06 0.941 – 1.2 0.331 440 822 exclusion phecode
427.9 Palpitations Circulatory System 1.08 1.01 – 1.15 0.024 1748 3146 exclusion phecode
428 Congestive heart failure; nonhypertensive Circulatory System 1.15 1.08 – 1.22 3.99e-06 2080 3117 exclusion phecode
428.1 Congestive heart failure (CHF) NOS Circulatory System 1.16 1.09 – 1.24 2.78e-06 1808 2929 exclusion phecode
428.2 Heart failure NOS Circulatory System 1.13 1.07 – 1.21 7.55e-05 1810 2822 exclusion phecode
428.3
Heart failure with reduced EF [Systolic or
Heart failure with reduced EF [Systolic or combined heart failure]
 Circulatory System 1.2 1.11 – 1.3 4.59e-06 1027 1937 exclusion phecode
428.4
Heart failure with preserved EF [Diastolic
Heart failure with preserved EF [Diastolic heart failure]
 Circulatory System 1.07 0.989 – 1.16 0.0886 932 1778 exclusion phecode
429
Ill-defined descriptions and complications of
Ill-defined descriptions and complications of heart disease
 Circulatory System 1.11 1.06 – 1.16 3.46e-06 4681 4529 exclusion phecode
429.1 Heart transplant/surgery Circulatory System 1.11 1.01 – 1.22 0.0249 669 1550 exclusion phecode
429.2 Abnormal function study of cardiovascular system Circulatory System 1.11 1.06 – 1.18 6.5e-05 2766 4064 exclusion phecode
429.3 Symptoms involving cardiovascular system Circulatory System 1.11 1.06 – 1.16 1.29e-05 3645 4527 exclusion phecode
429.9 Cardiac complications, not elsewhere classified Circulatory System 1.17 1.04 – 1.32 0.0113 348 884 exclusion phecode
430 Intracranial hemorrhage Circulatory System 1.06 0.929 – 1.21 0.381 262 1573 exclusion phecode
430.1 Subarachnoid hemorrhage Circulatory System 1.06 0.839 – 1.34 0.619 89 477 exclusion phecode
430.2 Intracerebral hemorrhage Circulatory System 1.09 0.891 – 1.32 0.416 116 661 exclusion phecode
430.3 Subdural hemorrhage Circulatory System 1.1 0.893 – 1.35 0.37 102 568 exclusion phecode
433 Cerebrovascular disease Circulatory System 1.09 1.03 – 1.15 0.00165 1974 5967 exclusion phecode
433.1 Occlusion and stenosis of precerebral arteries Circulatory System 1.08 1 – 1.17 0.0383 907 3195 exclusion phecode
433.11
Occlusion of cerebral arteries, with cerebral
Occlusion of cerebral arteries, with cerebral infarction
 Circulatory System 1.18 0.987 – 1.42 0.0691 132 551 exclusion phecode
433.12 Cerebral atherosclerosis Circulatory System 1.44 0.972 – 2.13 0.0693 49 181 exclusion phecode
433.2 Occlusion of cerebral arteries Circulatory System 1.1 1.03 – 1.19 0.00765 895 4145 exclusion phecode
433.21
Cerebral artery occlusion, with cerebral
Cerebral artery occlusion, with cerebral infarction
 Circulatory System 1.1 1.02 – 1.18 0.0113 868 4020 exclusion phecode
433.3 Cerebral ischemia Circulatory System 1.08 1.01 – 1.16 0.019 1077 4352 exclusion phecode
433.31 Transient cerebral ischemia Circulatory System 1.08 1 – 1.16 0.045 944 3957 exclusion phecode
433.5 Cerebral aneurysm Circulatory System 1.05 0.855 – 1.28 0.655 110 788 exclusion phecode
433.6 Acute, but ill-defined cerebrovascular disease Circulatory System 1.07 0.939 – 1.23 0.296 283 1004 exclusion phecode
433.8 Late effects of cerebrovascular disease Circulatory System 1.08 0.956 – 1.22 0.217 321 1355 exclusion phecode
440 Atherosclerosis Circulatory System 1.08 1.02 – 1.16 0.0146 1322 3265 exclusion phecode
440.1 Atherosclerosis of renal artery Circulatory System 1.08 0.865 – 1.34 0.511 118 343 exclusion phecode
440.2 Atherosclerosis of the extremities Circulatory System 1.07 0.987 – 1.16 0.102 866 2432 exclusion phecode
440.21
Atherosclerosis of native arteries of the
Atherosclerosis of native arteries of the extremities with ulceration or gangrene
 Circulatory System 1.09 0.926 – 1.29 0.291 184 651 exclusion phecode
440.22
Atherosclerosis of native arteries of the
Atherosclerosis of native arteries of the extremities with intermittent claudication
 Circulatory System 1.07 0.97 – 1.17 0.186 627 1828 exclusion phecode
440.9 Atherosclerosis of aorta Circulatory System 1.17 1.05 – 1.3 0.00494 475 1362 exclusion phecode
441 Vascular insufficiency of intestine Circulatory System 0.95 0.816 – 1.1 0.503 231 883 exclusion phecode
441.1 Acute vascular insufficiency of intestine Circulatory System 0.851 0.687 – 1.06 0.143 112 418 exclusion phecode
441.2 Chronic vascular insufficiency of intestine Circulatory System 1.05 0.794 – 1.39 0.736 64 277 exclusion phecode
442 Other aneurysm Circulatory System 1.04 0.973 – 1.12 0.237 1158 3401 exclusion phecode
442.1 Aortic aneurysm Circulatory System 1.05 0.97 – 1.13 0.244 940 2672 exclusion phecode
442.11 Abdominal aortic aneurysm Circulatory System 1.08 0.975 – 1.19 0.146 509 1708 exclusion phecode
442.2 Aneurysm of iliac artery Circulatory System 1.09 0.867 – 1.38 0.454 90 304 exclusion phecode
442.3 Aneurysm of artery of lower extremity Circulatory System 1.12 0.866 – 1.44 0.395 83 266 exclusion phecode
442.4 Arterial dissection Circulatory System 0.87 0.689 – 1.1 0.24 85 271 exclusion phecode
442.8 Aneurysm of other specified artery Circulatory System 1.1 0.92 – 1.33 0.287 148 621 exclusion phecode
443 Peripheral vascular disease Circulatory System 1.12 1.05 – 1.19 0.000445 1382 4093 exclusion phecode
443.1 Raynaud's syndrome Circulatory System 1.1 0.953 – 1.26 0.201 240 1213 exclusion phecode
443.7
Peripheral angiopathy in diseases classified
Peripheral angiopathy in diseases classified elsewhere
 Circulatory System 1.04 0.877 – 1.24 0.635 170 626 exclusion phecode
443.8 Other specified peripheral vascular diseases Circulatory System 1.12 1.05 – 1.2 0.00101 1118 3679 exclusion phecode
443.9 Peripheral vascular disease, unspecified Circulatory System 1.12 1.05 – 1.2 0.00112 1136 3199 exclusion phecode
444 Arterial embolism and thrombosis Circulatory System 1.08 0.963 – 1.21 0.185 390 1423 exclusion phecode
444.1
Arterial embolism and thrombosis of lower
Arterial embolism and thrombosis of lower extremity artery
 Circulatory System 1.09 0.912 – 1.3 0.349 162 568 exclusion phecode
444.2 Embolism and thrombosis of abdominal aorta Circulatory System 1.07 0.816 – 1.4 0.622 76 244 exclusion phecode
446 Polyarteritis nodosa and allied conditions Circulatory System 1.08 0.918 – 1.26 0.367 185 819 exclusion phecode
446.4 Wegener's granulomatosis Circulatory System 1.37 0.967 – 1.94 0.0769 39 193 exclusion phecode
446.5 Giant cell arteritis Circulatory System 1.04 0.702 – 1.53 0.855 33 117 exclusion phecode
446.9 Arteritis NOS Circulatory System 1.03 0.838 – 1.26 0.795 119 542 exclusion phecode
447 Other disorders of arteries and arterioles Circulatory System 1.04 0.976 – 1.11 0.218 1220 3675 exclusion phecode
447.1 Stricture of artery Circulatory System 1.11 0.96 – 1.28 0.16 255 828 exclusion phecode
447.7 Aortic ectasia Circulatory System 0.952 0.854 – 1.06 0.37 432 1374 exclusion phecode
448 Disease of capillaries Circulatory System 0.927 0.834 – 1.03 0.161 423 2114 exclusion phecode
450 Noninfectious disorders of lymphatic channels Circulatory System 0.985 0.9 – 1.08 0.734 544 4198 exclusion phecode
451 Phlebitis and thrombophlebitis Circulatory System 1.01 0.885 – 1.15 0.873 271 1178 exclusion phecode
451.2
Phlebitis and thrombophlebitis of lower
Phlebitis and thrombophlebitis of lower extremities
 Circulatory System 0.992 0.791 – 1.24 0.941 88 407 exclusion phecode
452 Other venous embolism and thrombosis Circulatory System 1.02 0.964 – 1.09 0.44 1474 4441 exclusion phecode
452.1 Iatrogenic pulmonary embolism and infarction Circulatory System 1 0.793 – 1.27 0.969 100 433 exclusion phecode
452.2 Deep vein thrombosis [DVT] Circulatory System 1.04 0.966 – 1.12 0.306 937 3985 exclusion phecode
452.8 Postphlebitic syndrome Circulatory System 0.912 0.645 – 1.29 0.603 32 224 exclusion phecode
453 Chronic venous hypertension Circulatory System 0.982 0.787 – 1.23 0.872 97 374 exclusion phecode
454 Varicose veins Circulatory System 0.943 0.878 – 1.01 0.111 973 3757 exclusion phecode
454.1 Varicose veins of lower extremity Circulatory System 0.946 0.877 – 1.02 0.154 876 3296 exclusion phecode
454.11 Varicose veins of lower extremity, symptomtic Circulatory System 0.931 0.85 – 1.02 0.123 615 2370 exclusion phecode
455 Hemorrhoids Circulatory System 1.07 1.01 – 1.13 0.0159 2201 4612 exclusion phecode
456 Chronic venous insufficiency [CVI] Circulatory System 0.949 0.89 – 1.01 0.113 1277 3892 exclusion phecode
457
Encounter for long-term (current) use of
Encounter for long-term (current) use of anticoagulants, antithrombotics, aspirin
 Circulatory System 1.13 1.05 – 1.23 0.00218 852 2324 exclusion phecode
457.2
Encounter for long-term (current) use of
Encounter for long-term (current) use of antiplatelets/antithrombotics
 Circulatory System 1.14 0.948 – 1.37 0.164 150 506 exclusion phecode
457.3 Encounter for long-term (current) use of aspirin Circulatory System 1.13 1.04 – 1.23 0.00346 802 2236 exclusion phecode
458 Hypotension Circulatory System 1.11 1.05 – 1.17 0.000167 2116 5153 exclusion phecode
458.1 Orthostatic hypotension Circulatory System 1.06 0.963 – 1.16 0.247 625 2289 exclusion phecode
458.2 Iatrogenic hypotension Circulatory System 1.07 0.964 – 1.18 0.207 494 1817 exclusion phecode
458.9 Hypotension NOS Circulatory System 1.1 1.05 – 1.17 0.000406 1940 4994 exclusion phecode
459 Other disorders of circulatory system Circulatory System 1.08 1.03 – 1.13 0.00178 2737 5607 exclusion phecode
459.1 Hemorrhage NOS Circulatory System 1.02 0.9 – 1.15 0.789 347 1451 exclusion phecode
459.7 Blood vessel replaced Circulatory System 1.14 1.03 – 1.26 0.0121 509 1952 exclusion phecode
459.9 Circulatory disease NEC Circulatory System 1.09 1.03 – 1.15 0.00116 2368 5371 exclusion phecode
464 Acute sinusitis Respiratory 0.946 0.896 – 0.998 0.0415 1924 4830 exclusion phecode
465
Acute upper respiratory infections of multiple
Acute upper respiratory infections of multiple or unspecified sites
 Respiratory 0.938 0.899 – 0.979 0.00351 3814 5406 exclusion phecode
465.2 Acute pharyngitis Respiratory 0.933 0.884 – 0.985 0.0116 2053 4764 exclusion phecode
465.4 Acute laryngitis and tracheitis Respiratory 0.901 0.75 – 1.08 0.269 147 702 exclusion phecode
470 Septal Deviations/Turbinate Hypertrophy Respiratory 0.965 0.875 – 1.06 0.474 484 2635 exclusion phecode
471 Nasal polyps Respiratory 0.974 0.826 – 1.15 0.75 151 981 exclusion phecode
472 Chronic pharyngitis and nasopharyngitis Respiratory 0.919 0.844 – 1 0.05 689 2867 exclusion phecode
473 Diseases of the larynx and vocal cords Respiratory 0.93 0.861 – 1 0.0667 805 3933 exclusion phecode
473.1 Chronic laryngitis Respiratory 0.762 0.505 – 1.15 0.193 27 120 exclusion phecode
473.3 Paralysis/spasm of vocal cords or larynx Respiratory 1.07 0.899 – 1.27 0.452 157 952 exclusion phecode
473.4 Voice disturbance Respiratory 0.964 0.884 – 1.05 0.403 627 3351 exclusion phecode
474 Acute and chronic tonsillitis Respiratory 0.891 0.779 – 1.02 0.093 283 1201 exclusion phecode
474.1 Acute tonsillitis Respiratory 0.951 0.762 – 1.19 0.657 104 451 exclusion phecode
474.2 Chronic tonsillitis and adenoiditis Respiratory 0.851 0.729 – 0.994 0.0424 214 939 exclusion phecode
475 Chronic sinusitis Respiratory 0.939 0.884 – 0.998 0.0414 1476 4360 exclusion phecode
475.9 Postnasal drip Respiratory 0.925 0.823 – 1.04 0.186 379 1632 exclusion phecode
476 Allergic rhinitis Respiratory 0.921 0.88 – 0.963 0.000346 3676 4423 exclusion phecode
477 Epistaxis or throat hemorrhage Respiratory 1.1 0.991 – 1.21 0.0737 490 1877 exclusion phecode
478 Throat pain Respiratory 0.997 0.817 – 1.22 0.975 127 646 exclusion phecode
479 Other upper respiratory disease Respiratory 0.958 0.906 – 1.01 0.125 1850 4404 exclusion phecode
480 Pneumonia Respiratory 1.05 1 – 1.11 0.042 2144 6201 exclusion phecode
480.1 Bacterial pneumonia Respiratory 1.16 1.05 – 1.27 0.00397 515 2103 exclusion phecode
480.11 Pneumococcal pneumonia Respiratory 1.19 1.04 – 1.37 0.0145 254 1037 exclusion phecode
480.12 Pseudomonal pneumonia Respiratory 1.11 0.849 – 1.45 0.441 76 254 exclusion phecode
480.13 MRSA pneumonia Respiratory 1.08 0.79 – 1.47 0.633 53 240 exclusion phecode
480.2 Viral pneumonia Respiratory 1.05 0.851 – 1.29 0.672 110 448 exclusion phecode
480.3 Pneumonia due to fungus (mycoses) Respiratory 1.25 0.957 – 1.62 0.102 71 309 exclusion phecode
480.5 Bronchopneumonia and lung abscess Respiratory 0.955 0.712 – 1.28 0.758 55 239 exclusion phecode
481 Influenza Respiratory 1.03 0.942 – 1.13 0.512 591 2674 exclusion phecode
483 Acute bronchitis and bronchiolitis Respiratory 0.993 0.937 – 1.05 0.827 1461 5219 exclusion phecode
495 Asthma Respiratory 0.986 0.938 – 1.04 0.567 2235 6145 exclusion phecode
495.1 Chronic obstructive asthma Respiratory 1 0.842 – 1.2 0.967 153 787 exclusion phecode
495.11 Chronic obstructive asthma with exacerbation Respiratory 1.29 0.913 – 1.83 0.148 48 206 exclusion phecode
495.2 Asthma with exacerbation Respiratory 1.01 0.924 – 1.11 0.805 573 3051 exclusion phecode
496 Chronic airway obstruction Respiratory 1.05 0.987 – 1.11 0.128 1459 5192 exclusion phecode
496.1 Emphysema Respiratory 1.04 0.952 – 1.13 0.412 612 3619 exclusion phecode
496.2 Chronic bronchitis Respiratory 1.05 0.988 – 1.12 0.113 1144 4873 exclusion phecode
496.21 Obstructive chronic bronchitis Respiratory 1.06 0.994 – 1.14 0.0734 1045 4667 exclusion phecode
496.3 Bronchiectasis Respiratory 1.17 1.01 – 1.36 0.0389 208 1154 exclusion phecode
497 Bronchitis Respiratory 1.01 0.939 – 1.1 0.714 792 3795 exclusion phecode
498 Acute bronchospasm Respiratory 0.948 0.816 – 1.1 0.489 220 953 exclusion phecode
499 Cystic fibrosis Respiratory 1.1 0.845 – 1.42 0.488 67 376 exclusion phecode
500 Lung disease due to external agents Respiratory 0.91 0.783 – 1.06 0.222 197 955 exclusion phecode
500.1 Extrinsic allergic alveolitis Respiratory 0.732 0.508 – 1.06 0.0948 35 150 exclusion phecode
500.2 Pneumoconiosis Respiratory 1.05 0.734 – 1.5 0.786 35 153 exclusion phecode
501 Pneumonitis due to inhalation of food or vomitus Respiratory 1.09 0.946 – 1.26 0.225 235 1136 exclusion phecode
502 Postinflammatory pulmonary fibrosis Respiratory 0.981 0.865 – 1.11 0.761 308 1442 exclusion phecode
503 Pulmonary congestion and hypostasis Respiratory 1.12 1 – 1.24 0.0426 448 1624 exclusion phecode
504 Other alveolar and parietoalveolar pneumonopathy Respiratory 1.02 0.885 – 1.18 0.765 228 1095 exclusion phecode
504.1 Idiopathic fibrosing alveolitis Respiratory 1.08 0.89 – 1.32 0.425 122 579 exclusion phecode
505 Other pulmonary inflamation or edema Respiratory 1.09 1.01 – 1.18 0.0341 834 2901 exclusion phecode
506 Empyema and pneumothorax Respiratory 1.11 1.04 – 1.19 0.00292 1066 4202 exclusion phecode
507 Pleurisy; pleural effusion Respiratory 1.08 1.01 – 1.15 0.0251 1152 4433 exclusion phecode
508
Pulmonary collapse; interstitial and
Pulmonary collapse; interstitial and compensatory emphysema
 Respiratory 1.1 1.03 – 1.19 0.00876 870 3907 exclusion phecode
509 Respiratory failure, insufficiency, arrest Respiratory 1.15 1.09 – 1.22 9.03e-07 1677 4953 exclusion phecode
509.1 Respiratory failure Respiratory 1.13 1.04 – 1.22 0.00246 802 3328 exclusion phecode
509.2 Respiratory insufficiency Respiratory 1.11 1 – 1.22 0.0481 513 2058 exclusion phecode
509.3
Pulmonary insufficiency or respiratory failure
Pulmonary insufficiency or respiratory failure following trauma and surgery
 Respiratory 1.11 1.02 – 1.2 0.0158 789 2829 exclusion phecode
509.8
Dependence on respirator [Ventilator] or
Dependence on respirator [Ventilator] or supplemental oxygen
 Respiratory 1.13 1.04 – 1.22 0.00402 717 2991 exclusion phecode
510 Other diseases of lung Respiratory 1.02 0.967 – 1.07 0.501 2036 6644 exclusion phecode
510.2 Lung transplant Respiratory 1.12 0.887 – 1.41 0.346 104 352 exclusion phecode
512 Other symptoms of respiratory system Respiratory 1.01 0.964 – 1.05 0.733 6300 3373 exclusion phecode
512.1 Wheezing Respiratory 0.958 0.87 – 1.06 0.385 613 1758 exclusion phecode
512.2 Painful respiration Respiratory 1.01 0.931 – 1.09 0.893 942 2631 exclusion phecode
512.3 Abnormal chest sounds Respiratory 0.958 0.789 – 1.16 0.666 153 363 exclusion phecode
512.7 Shortness of breath Respiratory 1.06 1.01 – 1.11 0.0269 3896 3353 exclusion phecode
512.8 Cough Respiratory 0.976 0.93 – 1.02 0.329 3808 3372 exclusion phecode
512.9 Other dyspnea Respiratory 1.03 0.983 – 1.08 0.201 3994 3364 exclusion phecode
513 Respiratory abnormalities Respiratory 1.05 1 – 1.09 0.0359 4577 5094 exclusion phecode
513.3 Hypoventilation Respiratory 0.981 0.876 – 1.1 0.742 398 1491 exclusion phecode
513.31 Apnea Respiratory 1.07 0.913 – 1.26 0.386 189 786 exclusion phecode
513.32 Orthopnea Respiratory 0.973 0.789 – 1.2 0.797 123 364 exclusion phecode
513.4 Hyperventilation Respiratory 1.17 1 – 1.35 0.0431 239 743 exclusion phecode
513.8 Disorders of diaphragm Respiratory 1.14 0.908 – 1.43 0.257 95 411 exclusion phecode
514 Abnormal findings examination of lungs Respiratory 1.01 0.951 – 1.06 0.843 1588 6667 exclusion phecode
514.1
Abnormal results of function study of pulmonary
Abnormal results of function study of pulmonary system
 Respiratory 1.09 0.89 – 1.32 0.417 120 582 exclusion phecode
514.2 Solitary pulmonary nodule Respiratory 0.995 0.925 – 1.07 0.882 865 5271 exclusion phecode
516 Abnormal sputum Respiratory 1.16 1.01 – 1.32 0.0295 281 1611 exclusion phecode
516.1 Hemoptysis Respiratory 1.25 1.08 – 1.44 0.00232 232 1327 exclusion phecode
519
Other diseases of respiratory system, not
Other diseases of respiratory system, not elsewhere classified
 Respiratory 1.03 0.978 – 1.08 0.293 2249 7145 exclusion phecode
519.1 Tracheostomy complications Respiratory 1.18 0.884 – 1.57 0.262 48 355 exclusion phecode
519.2 Respiratory complications Respiratory 1.06 0.9 – 1.25 0.485 169 773 exclusion phecode
519.8 Other diseases of respiratory system, NEC Respiratory 0.959 0.873 – 1.05 0.388 512 3067 exclusion phecode
519.9
Symptoms involving respiratory system and other
Symptoms involving respiratory system and other chest symptoms
 Respiratory 1.05 0.991 – 1.11 0.1 1721 6322 exclusion phecode
520 Disorders of tooth development Digestive 0.904 0.692 – 1.18 0.455 56 672 exclusion phecode
520.1 Hereditary disturbances in tooth structure Digestive 0.869 0.602 – 1.26 0.455 29 331 exclusion phecode
520.2 Disturbances in tooth eruption Digestive 0.943 0.622 – 1.43 0.784 24 356 exclusion phecode
521 Diseases of hard tissues of teeth Digestive 1.03 0.895 – 1.18 0.688 223 1741 exclusion phecode
521.1 Dental caries Digestive 1.03 0.888 – 1.19 0.722 202 1618 exclusion phecode
521.2 Dental abrasion, erosion and attrition Digestive 1.26 0.719 – 2.2 0.422 17 83 exclusion phecode
522 Diseases of pulp and periapical tissues Digestive 1.06 0.903 – 1.24 0.477 179 1104 exclusion phecode
522.5 Periapical abscess Digestive 1.03 0.868 – 1.21 0.757 166 935 exclusion phecode
523 Gingival and periodontal diseases Digestive 0.958 0.829 – 1.11 0.567 207 1410 exclusion phecode
523.1 Gingivitis Digestive 0.762 0.559 – 1.04 0.0846 49 272 exclusion phecode
523.3 Periodontitis (acute or chronic) Digestive 0.944 0.775 – 1.15 0.564 109 710 exclusion phecode
523.31 Acute periodontitis Digestive 0.942 0.751 – 1.18 0.602 88 595 exclusion phecode
523.32 Chronic periodontitis Digestive 0.895 0.622 – 1.29 0.552 32 233 exclusion phecode
524 Dentofacial anomalies, including malocclusion Digestive 0.685 0.482 – 0.973 0.0344 40 566 exclusion phecode
524.3 Anomalies of tooth position/malocclusion Digestive 0.656 0.416 – 1.03 0.07 21 325 exclusion phecode
525
Other diseases of the teeth and supporting
Other diseases of the teeth and supporting structures
 Digestive 1.02 0.893 – 1.16 0.796 265 1970 exclusion phecode
525.1 Loss of teeth or edentulism Digestive 1.06 0.828 – 1.36 0.64 72 683 exclusion phecode
526 Diseases of the jaws Digestive 0.958 0.881 – 1.04 0.32 627 4938 exclusion phecode
526.1 Cysts of the jaws Digestive 0.956 0.66 – 1.39 0.813 33 418 exclusion phecode
526.3 Anomalies of jaw size/symmetry Digestive 0.77 0.519 – 1.14 0.195 27 341 exclusion phecode
526.4 Temporomandibular joint disorders Digestive 0.997 0.894 – 1.11 0.951 385 2778 exclusion phecode
526.41 Temporomandibular joint disorder, unspecified Digestive 0.948 0.837 – 1.07 0.404 291 2172 exclusion phecode
526.42 Arthralgia/ankylosis of temporomandibular joint Digestive 0.966 0.817 – 1.14 0.691 157 1339 exclusion phecode
526.5 Inflammatory conditions of jaw Digestive 0.87 0.637 – 1.19 0.381 39 539 exclusion phecode
526.8 Exostosis of jaw Digestive 0.66 0.346 – 1.26 0.208 10 102 exclusion phecode
526.9 Jaw disease NOS Digestive 0.833 0.665 – 1.04 0.113 82 944 exclusion phecode
527 Diseases of the salivary glands Digestive 1.03 0.934 – 1.13 0.568 472 3605 exclusion phecode
527.1 Hypertrophy of salivary gland Digestive 1.02 0.631 – 1.64 0.948 17 128 exclusion phecode
527.2 Sialoadenitis Digestive 0.931 0.765 – 1.13 0.472 114 782 exclusion phecode
527.7 Disturbance of salivary secretion Digestive 1.06 0.929 – 1.21 0.392 268 1945 exclusion phecode
527.8 Other specified diseases of the salivary glands Digestive 1.17 0.901 – 1.53 0.235 59 494 exclusion phecode
528
Diseases of the oral soft tissues, excluding
Diseases of the oral soft tissues, excluding lesions specific for gingiva and tongue
 Digestive 0.955 0.882 – 1.03 0.262 698 5234 exclusion phecode
528.1 Stomatitis and mucositis Digestive 0.876 0.758 – 1.01 0.0708 215 1333 exclusion phecode
528.11 Stomatitis and mucositis (ulcerative) Digestive 0.808 0.627 – 1.04 0.102 67 401 exclusion phecode
528.12 Oral aphthae Digestive 0.843 0.669 – 1.06 0.147 89 479 exclusion phecode
528.3 Cellulitis and abscess of oral soft tissues Digestive 0.923 0.695 – 1.23 0.582 47 425 exclusion phecode
528.4 Cysts of oral soft tissues Digestive 1.22 0.803 – 1.87 0.346 22 225 exclusion phecode
528.41 Cyst of the salivary gland Digestive 1.04 0.638 – 1.69 0.88 16 139 exclusion phecode
528.5 Diseases of lips Digestive 0.941 0.785 – 1.13 0.513 148 966 exclusion phecode
528.6 Leukoplakia of oral mucosa Digestive 1.02 0.704 – 1.49 0.903 24 277 exclusion phecode
528.7 Sialolithiasis Digestive 1.47 1.07 – 2.02 0.0185 47 301 exclusion phecode
529 Diseases and other conditions of the tongue Digestive 1.1 0.939 – 1.28 0.245 182 1436 exclusion phecode
529.1 Glossitis Digestive 1.13 0.822 – 1.55 0.453 42 245 exclusion phecode
529.6 Glossodynia Digestive 1.08 0.782 – 1.5 0.628 43 360 exclusion phecode
530 Diseases of esophagus Digestive 0.99 0.949 – 1.03 0.644 4685 4629 exclusion phecode
530.1 Esophagitis, GERD and related diseases Digestive 0.993 0.951 – 1.04 0.729 4584 4629 exclusion phecode
530.11 GERD Digestive 0.99 0.949 – 1.03 0.652 4466 4628 exclusion phecode
530.12 Ulcer of esophagus Digestive 0.967 0.809 – 1.16 0.715 155 702 exclusion phecode
530.13 Barrett's esophagus Digestive 0.941 0.816 – 1.09 0.406 214 1320 exclusion phecode
530.14 Reflux esophagitis Digestive 0.94 0.867 – 1.02 0.13 747 3050 exclusion phecode
530.15 Eosinophilic esophagitis Digestive 0.779 0.585 – 1.04 0.0869 66 369 exclusion phecode
530.2 Esophageal bleeding (varices/hemorrhage) Digestive 0.975 0.848 – 1.12 0.718 247 1130 exclusion phecode
530.3 Stricture and stenosis of esophagus Digestive 0.933 0.818 – 1.07 0.307 257 1468 exclusion phecode
530.5 Disorders of esophageal motility Digestive 1.1 0.926 – 1.31 0.278 161 916 exclusion phecode
530.6 Diverticulum of esophagus, acquired Digestive 1.44 0.83 – 2.48 0.195 16 208 exclusion phecode
530.7 Gastroesophageal laceration-hemorrhage syndrome Digestive 0.683 0.477 – 0.978 0.0372 39 157 exclusion phecode
530.9 Heartburn Digestive 0.901 0.819 – 0.991 0.0312 520 2574 exclusion phecode
531 Peptic ulcer (excl. esophageal) Digestive 0.989 0.914 – 1.07 0.774 756 4293 exclusion phecode
531.1 Hemorrhage from gastrointestinal ulcer Digestive 0.978 0.835 – 1.15 0.786 172 806 exclusion phecode
531.2 Gastric ulcer Digestive 0.992 0.893 – 1.1 0.877 439 2531 exclusion phecode
531.3 Duodenal ulcer Digestive 0.991 0.849 – 1.16 0.906 191 978 exclusion phecode
531.4 Peptic ulcer, site unspecified Digestive 0.881 0.779 – 0.997 0.0442 316 1750 exclusion phecode
531.5 Gastrojejunal ulcer Digestive 1.15 0.869 – 1.53 0.323 59 279 exclusion phecode
532 Dysphagia Digestive 0.974 0.918 – 1.03 0.371 1608 4368 exclusion phecode
535 Gastritis and duodenitis Digestive 1.01 0.941 – 1.08 0.841 1061 5159 exclusion phecode
535.1 Acute gastritis Digestive 1.02 0.914 – 1.13 0.76 420 2326 exclusion phecode
535.2 Atrophic gastritis Digestive 0.923 0.756 – 1.13 0.428 118 616 exclusion phecode
535.6 Duodenitis Digestive 1.04 0.862 – 1.24 0.707 138 663 exclusion phecode
535.8 Other specified gastritis Digestive 0.945 0.825 – 1.08 0.415 261 1292 exclusion phecode
535.9 Gastritis and duodenitis, NOS Digestive 0.978 0.888 – 1.08 0.652 500 2461 exclusion phecode
536 Disorders of function of stomach Digestive 1.01 0.949 – 1.08 0.671 1084 5166 exclusion phecode
536.3 Gastroparesis Digestive 1.12 0.991 – 1.27 0.0702 303 1647 exclusion phecode
536.7
Complications of gastrostomy, colostomy and
Complications of gastrostomy, colostomy and enterostomy
 Digestive 1.13 0.92 – 1.38 0.249 108 637 exclusion phecode
536.8
Dyspepsia and other specified disorders of
Dyspepsia and other specified disorders of function of stomach
 Digestive 0.977 0.905 – 1.05 0.552 823 4075 exclusion phecode
537 Other disorders of stomach and duodenum Digestive 1.06 0.995 – 1.12 0.0727 1292 5626 exclusion phecode
537.1 Lesions of stomach and duodenum Digestive 0.94 0.749 – 1.18 0.594 94 379 exclusion phecode
539 Bariatric surgery Digestive 0.925 0.844 – 1.01 0.0932 574 2926 exclusion phecode
540 Appendiceal conditions Digestive 0.992 0.843 – 1.17 0.922 176 1004 exclusion phecode
540.1 Appendicitis Digestive 1.03 0.864 – 1.22 0.765 153 853 exclusion phecode
540.11 Acute appendicitis Digestive 1.04 0.858 – 1.25 0.712 126 718 exclusion phecode
550 Abdominal hernia Digestive 0.989 0.941 – 1.04 0.663 2113 7060 exclusion phecode
550.1 Inguinal hernia Digestive 0.902 0.825 – 0.985 0.0224 600 3158 exclusion phecode
550.2 Diaphragmatic hernia Digestive 0.983 0.913 – 1.06 0.649 844 4953 exclusion phecode
550.3 Femoral hernia Digestive 0.92 0.667 – 1.27 0.612 43 246 exclusion phecode
550.4 Umbilical hernia Digestive 0.991 0.896 – 1.1 0.853 473 2487 exclusion phecode
550.5 Ventral hernia Digestive 1.05 0.965 – 1.13 0.276 737 4045 exclusion phecode
550.6 Incisional hernia Digestive 1.01 0.913 – 1.13 0.804 414 2424 exclusion phecode
555
Inflammatory bowel disease and other
Inflammatory bowel disease and other gastroenteritis and colitis
 Digestive 1.04 0.934 – 1.16 0.469 411 2189 exclusion phecode
555.1 Regional enteritis Digestive 1.04 0.906 – 1.2 0.549 245 1242 exclusion phecode
555.2 Ulcerative colitis Digestive 1.09 0.947 – 1.25 0.232 264 1362 exclusion phecode
555.21 Ulcerative colitis (chronic) Digestive 1.08 0.911 – 1.29 0.362 171 765 exclusion phecode
556 Ulceration of the lower GI tract Digestive 0.93 0.809 – 1.07 0.308 274 1013 exclusion phecode
556.1 Ulceration of intestine Digestive 0.908 0.782 – 1.05 0.206 238 856 exclusion phecode
556.11
Angiodysplasia of intestine (without mention of
Angiodysplasia of intestine (without mention of hemorrhage)
 Digestive 0.816 0.652 – 1.02 0.0746 109 397 exclusion phecode
557 Intestinal malabsorption (non-celiac) Digestive 0.877 0.804 – 0.955 0.00261 704 2540 exclusion phecode
557.1 Celiac disease Digestive 0.961 0.794 – 1.16 0.684 143 697 exclusion phecode
558 Noninfectious gastroenteritis Digestive 0.999 0.934 – 1.07 0.974 1195 3873 exclusion phecode
559 Ileostomy status Digestive 1.11 0.961 – 1.28 0.157 233 1200 exclusion phecode
560 Intestinal obstruction without mention of hernia Digestive 0.986 0.917 – 1.06 0.716 952 3476 exclusion phecode
560.1 Paralytic ileus Digestive 1.04 0.942 – 1.15 0.425 492 2136 exclusion phecode
560.2 Impaction of intestine Digestive 0.808 0.668 – 0.978 0.0288 147 612 exclusion phecode
560.3 Peritoneal or intestinal adhesions Digestive 0.949 0.755 – 1.19 0.653 97 365 exclusion phecode
560.4 Other intestinal obstruction Digestive 0.964 0.877 – 1.06 0.44 559 2229 exclusion phecode
561 Symptoms involving digestive system Digestive 0.922 0.852 – 0.996 0.04 876 3234 exclusion phecode
562 Diverticulosis and diverticulitis Digestive 0.935 0.884 – 0.99 0.0201 2298 3398 exclusion phecode
562.1 Diverticulosis Digestive 0.936 0.885 – 0.991 0.0232 2280 3388 exclusion phecode
562.2 Diverticulitis Digestive 0.843 0.764 – 0.931 0.000754 517 2200 exclusion phecode
564 Functional digestive disorders Digestive 0.991 0.946 – 1.04 0.704 3517 4203 exclusion phecode
564.1 Irritable Bowel Syndrome Digestive 0.95 0.883 – 1.02 0.165 990 3327 exclusion phecode
564.9 Personal history of diseases of digestive system Digestive 0.974 0.907 – 1.05 0.473 1030 3645 exclusion phecode
565 Anal and rectal conditions Digestive 1.03 0.968 – 1.1 0.346 1212 5239 exclusion phecode
565.1 Anal and rectal polyp Digestive 1.04 0.95 – 1.15 0.376 522 2405 exclusion phecode
567 Peritonitis and retroperitoneal infections Digestive 1.03 0.93 – 1.14 0.551 456 2047 exclusion phecode
568 Other disorders of peritoneum Digestive 1.06 0.957 – 1.17 0.277 471 2685 exclusion phecode
568.1
Peritoneal adhesions (postoperative)
Peritoneal adhesions (postoperative) (postinfection)
 Digestive 1.05 0.928 – 1.19 0.441 316 1918 exclusion phecode
569 Other disorders of intestine Digestive 1.01 0.969 – 1.06 0.542 2786 5893 exclusion phecode
569.1 Toxic gastroenteritis and colitis Digestive 1.06 0.866 – 1.3 0.562 114 537 exclusion phecode
569.2 Gastrointestinal complications Digestive 1.06 0.955 – 1.17 0.276 456 2294 exclusion phecode
571 Chronic liver disease and cirrhosis Digestive 1.03 0.973 – 1.09 0.317 1600 5284 exclusion phecode
571.5 Other chronic nonalcoholic liver disease Digestive 1.01 0.956 – 1.07 0.652 1506 5231 exclusion phecode
571.51 Cirrhosis of liver without mention of alcohol Digestive 1.05 0.946 – 1.18 0.336 406 1816 exclusion phecode
571.6 Primary biliary cirrhosis Digestive 1.05 0.813 – 1.37 0.693 77 325 exclusion phecode
571.8
Liver abscess and sequelae of chronic liver
Liver abscess and sequelae of chronic liver disease
 Digestive 1.14 1.02 – 1.28 0.0196 377 1678 exclusion phecode
571.81 Portal hypertension Digestive 1.09 0.946 – 1.25 0.24 252 1014 exclusion phecode
572 Ascites (non malignant) Digestive 1.09 1 – 1.17 0.0417 770 3606 exclusion phecode
573 Other disorders of liver Digestive 1.01 0.958 – 1.07 0.687 1837 5497 exclusion phecode
573.1 Chronic passive congestion of liver Digestive 1.06 0.82 – 1.36 0.677 92 227 exclusion phecode
573.2 Liver replaced by transplant Digestive 1.09 0.905 – 1.31 0.368 162 494 exclusion phecode
573.3 Hepatomegaly Digestive 0.986 0.819 – 1.19 0.88 137 880 exclusion phecode
573.4 Acute and subacute necrosis of liver Digestive 1.17 0.971 – 1.42 0.0978 144 547 exclusion phecode
573.5 Jaundice (not of newborn) Digestive 1.06 0.947 – 1.19 0.307 375 1678 exclusion phecode
573.6
Nonspecific elevation of levels of transaminase
Nonspecific elevation of levels of transaminase or lactic acid dehydrogenase [LDH]
 Digestive 1.04 0.979 – 1.11 0.183 1180 4499 exclusion phecode
573.7 Abnormal results of function study of liver Digestive 1.03 0.966 – 1.09 0.383 1287 4674 exclusion phecode
573.9 Abnormal serum enzyme levels Digestive 1.06 1 – 1.11 0.0372 1962 5555 exclusion phecode
574 Cholelithiasis and cholecystitis Digestive 1.01 0.942 – 1.07 0.877 1106 6052 exclusion phecode
574.1 Cholelithiasis Digestive 0.98 0.917 – 1.05 0.553 1022 5683 exclusion phecode
574.11 Cholelithiasis with acute cholecystitis Digestive 0.929 0.774 – 1.11 0.429 139 701 exclusion phecode
574.12 Cholelithiasis with other cholecystitis Digestive 1.02 0.87 – 1.19 0.824 180 1091 exclusion phecode
574.2 Calculus of bile duct Digestive 1.02 0.907 – 1.16 0.7 319 1705 exclusion phecode
574.3 Cholecystitis without cholelithiasis Digestive 1.01 0.9 – 1.14 0.835 325 1705 exclusion phecode
575 Other biliary tract disease Digestive 1.01 0.935 – 1.09 0.798 780 4392 exclusion phecode
575.1 Cholangitis Digestive 1.14 0.942 – 1.37 0.182 133 706 exclusion phecode
575.2 Obstruction of bile duct Digestive 1.08 0.921 – 1.26 0.35 192 1199 exclusion phecode
575.6 Cholesterolosis of gallbladder Digestive 0.925 0.711 – 1.2 0.56 62 381 exclusion phecode
575.7 Other disorders of gallbladder Digestive 0.968 0.864 – 1.08 0.572 352 1862 exclusion phecode
575.8 Other disorders of biliary tract Digestive 1.03 0.927 – 1.15 0.558 390 2254 exclusion phecode
575.9
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of biliary tract
 Digestive 0.934 0.751 – 1.16 0.544 106 523 exclusion phecode
577 Diseases of pancreas Digestive 1.06 0.981 – 1.15 0.139 768 4855 exclusion phecode
577.1 Acute pancreatitis Digestive 1.04 0.935 – 1.15 0.504 433 2674 exclusion phecode
577.2 Chronic pancreatitis Digestive 0.965 0.83 – 1.12 0.643 196 1081 exclusion phecode
577.3 Cyst and pseudocyst of pancreas Digestive 1.06 0.911 – 1.23 0.45 206 1299 exclusion phecode
578 Gastrointestinal hemorrhage Digestive 1.01 0.954 – 1.06 0.843 1857 6346 exclusion phecode
578.1 Hematemesis Digestive 0.958 0.826 – 1.11 0.569 220 913 exclusion phecode
578.2 Blood in stool Digestive 0.992 0.93 – 1.06 0.814 1165 4716 exclusion phecode
578.8 Hemorrhage of rectum and anus Digestive 1.04 0.965 – 1.12 0.317 899 3838 exclusion phecode
578.9 Hemorrhage of gastrointestinal tract Digestive 1.03 0.95 – 1.12 0.464 727 2824 exclusion phecode
579 Other symptoms involving abdomen and pelvis Digestive 1.01 0.955 – 1.07 0.682 1494 5792 exclusion phecode
579.2 Splenomegaly Digestive 1.06 0.942 – 1.2 0.315 335 1347 exclusion phecode
579.8 Nonspecific abnormal findings in stool contents Digestive 0.99 0.907 – 1.08 0.814 639 2641 exclusion phecode
580 Nephritis; nephrosis; renal sclerosis Genitourinary 1.09 1.02 – 1.17 0.017 1099 2676 exclusion phecode
580.1 Glomerulonephritis Genitourinary 1.15 0.986 – 1.34 0.0746 236 728 exclusion phecode
580.11 Proliferative glomerulonephritis Genitourinary 1.1 0.849 – 1.43 0.464 79 262 exclusion phecode
580.12 Non-proliferative glomerulonephritis Genitourinary 1.27 0.927 – 1.73 0.138 64 208 exclusion phecode
580.13 Acute glomerulonephritis, NOS Genitourinary 1.21 0.836 – 1.76 0.31 38 117 exclusion phecode
580.14 Chronic glomerulonephritis, NOS Genitourinary 1.06 0.879 – 1.28 0.534 177 493 exclusion phecode
580.2
Nephrotic syndrome without mention of
Nephrotic syndrome without mention of glomerulonephritis
 Genitourinary 1.2 0.96 – 1.5 0.109 108 414 exclusion phecode
580.3
Nephritis and nephropathy without mention of
Nephritis and nephropathy without mention of glomerulonephritis
 Genitourinary 1.08 1 – 1.16 0.0484 953 2183 exclusion phecode
580.31
Nephritis and nephropathy in diseases
Nephritis and nephropathy in diseases classified elsewhere
 Genitourinary 1.07 0.978 – 1.17 0.145 723 1552 exclusion phecode
580.32
Nephritis and nephropathy with pathological
Nephritis and nephropathy with pathological lesion
 Genitourinary 1.12 0.991 – 1.26 0.0711 359 1276 exclusion phecode
580.4 Renal sclerosis, NOS Genitourinary 1.03 0.858 – 1.23 0.769 155 575 exclusion phecode
585 Renal failure Genitourinary 1.09 1.04 – 1.15 0.00025 2990 5042 exclusion phecode
585.1 Acute renal failure Genitourinary 1.12 1.06 – 1.18 9.85e-05 1961 4223 exclusion phecode
585.2 Renal failure NOS Genitourinary 1.05 0.944 – 1.17 0.368 459 1423 exclusion phecode
585.3 Chronic renal failure [CKD] Genitourinary 1.09 1.03 – 1.15 0.0015 2350 4621 exclusion phecode
585.31 Renal dialysis Genitourinary 1.06 0.947 – 1.18 0.321 442 1294 exclusion phecode
585.32 End stage renal disease Genitourinary 1.08 0.979 – 1.19 0.126 603 1693 exclusion phecode
585.33 Chronic Kidney Disease, Stage III Genitourinary 1.12 1.05 – 1.19 0.000287 1584 3459 exclusion phecode
585.34 Chronic Kidney Disease, Stage IV Genitourinary 1.12 1.01 – 1.23 0.0291 549 1599 exclusion phecode
585.4 Chronic kidney disease, Stage I or II Genitourinary 1.11 1.02 – 1.21 0.0178 694 2009 exclusion phecode
586 Other disorders of the kidney and ureters Genitourinary 1.09 1.04 – 1.14 0.000559 2675 5308 exclusion phecode
586.1 Anatomical abnormatilies of kidney and ureters Genitourinary 1.05 0.868 – 1.28 0.601 120 566 exclusion phecode
586.11 Small kidney Genitourinary 1.11 0.867 – 1.41 0.418 75 385 exclusion phecode
586.12 Vesicoureteral reflux Genitourinary 0.887 0.617 – 1.28 0.517 42 196 exclusion phecode
586.2 Cyst of kidney, acquired Genitourinary 1.06 0.958 – 1.16 0.275 508 2087 exclusion phecode
586.3 Vascular disorders of kidney/hypertrophy Genitourinary 1.09 0.873 – 1.35 0.46 104 329 exclusion phecode
586.4 Stricture/obstruction of ureter Genitourinary 1.03 0.93 – 1.13 0.618 477 2567 exclusion phecode
587 Kidney replaced by transpant Genitourinary 1.07 0.964 – 1.19 0.2 510 1394 exclusion phecode
588 Disorders resulting from impaired renal function Genitourinary 1.07 0.975 – 1.18 0.148 606 1691 exclusion phecode
588.1 Renal osteodystrophy Genitourinary 1.08 0.922 – 1.27 0.335 206 479 exclusion phecode
588.2 Secondary hyperparathyroidism (of renal origin) Genitourinary 1.1 0.985 – 1.23 0.0905 465 1396 exclusion phecode
589 Abnormal results of function study of kidney Genitourinary 1.13 1.03 – 1.25 0.0122 529 1706 exclusion phecode
590 Pyelonephritis Genitourinary 0.987 0.899 – 1.08 0.785 567 2369 exclusion phecode
591 Urinary tract infection Genitourinary 1.01 0.966 – 1.06 0.616 3173 5400 exclusion phecode
592 Cystitis and urethritis Genitourinary 1.02 0.951 – 1.09 0.592 1076 3953 exclusion phecode
592.1 Cystitis Genitourinary 1.02 0.955 – 1.1 0.498 1031 3789 exclusion phecode
592.11 Acute cystitis Genitourinary 1.03 0.949 – 1.12 0.462 718 2693 exclusion phecode
592.12 Chronic cystitis Genitourinary 0.876 0.681 – 1.13 0.302 78 397 exclusion phecode
592.13 Chronic interstitial cystitis Genitourinary 0.96 0.77 – 1.2 0.719 88 623 exclusion phecode
592.2 Urethritis and urethral syndrome Genitourinary 0.957 0.736 – 1.24 0.742 69 384 exclusion phecode
593 Hematuria Genitourinary 1.03 0.972 – 1.09 0.342 1752 5321 exclusion phecode
593.1 Gross hematuria Genitourinary 0.966 0.883 – 1.06 0.451 582 2752 exclusion phecode
593.2 Microscopic hematuria Genitourinary 1.07 0.965 – 1.2 0.191 410 1779 exclusion phecode
594 Urinary calculus Genitourinary 0.965 0.915 – 1.02 0.181 1735 7443 exclusion phecode
594.1 Calculus of kidney Genitourinary 0.966 0.915 – 1.02 0.215 1643 7407 exclusion phecode
594.2 Calculus of lower urinary tract Genitourinary 1.06 0.869 – 1.3 0.548 107 810 exclusion phecode
594.3 Calculus of ureter Genitourinary 0.995 0.9 – 1.1 0.922 444 2740 exclusion phecode
594.8 Renal colic Genitourinary 1.06 0.853 – 1.31 0.612 109 694 exclusion phecode
595 Hydronephrosis Genitourinary 0.951 0.861 – 1.05 0.315 463 3189 exclusion phecode
596 Other disorders of bladder Genitourinary 0.991 0.923 – 1.06 0.801 889 5593 exclusion phecode
596.1 Bladder neck obstruction Genitourinary 0.882 0.71 – 1.1 0.257 102 867 exclusion phecode
596.5 Functional disorders of bladder Genitourinary 0.979 0.895 – 1.07 0.65 551 3469 exclusion phecode
597 Other disorders of urethra and urinary tract Genitourinary 1.06 0.932 – 1.2 0.378 271 2411 exclusion phecode
597.1 Urethral stricture (not specified as infectious) Genitourinary 1.07 0.894 – 1.27 0.478 140 1307 exclusion phecode
597.2 Urinary complications NEC Genitourinary 1.08 0.952 – 1.23 0.223 257 2127 exclusion phecode
597.8 Urethral hypermobility/ISD Genitourinary 0.919 0.643 – 1.32 0.645 34 365 exclusion phecode
598 Abnormal findings on examination of urine Genitourinary 1.06 0.783 – 1.44 0.697 51 315 exclusion phecode
598.4 Other cells and casts in urine Genitourinary 1.08 0.776 – 1.49 0.66 44 285 exclusion phecode
599 Other symptoms/disorders or the urinary system Genitourinary 1.01 0.965 – 1.05 0.726 4132 5084 exclusion phecode
599.1 Urinary obstruction Genitourinary 0.947 0.829 – 1.08 0.422 256 1263 exclusion phecode
599.2 Retention of urine Genitourinary 0.989 0.929 – 1.05 0.726 1445 4497 exclusion phecode
599.3 Dysuria Genitourinary 0.983 0.926 – 1.04 0.569 1547 4655 exclusion phecode
599.4 Urinary incontinence Genitourinary 0.976 0.919 – 1.04 0.439 1516 4465 exclusion phecode
599.5 Frequency of urination and polyuria Genitourinary 0.994 0.94 – 1.05 0.827 1816 4848 exclusion phecode
599.6 Oliguria and anuria Genitourinary 1 0.879 – 1.14 0.965 289 942 exclusion phecode
599.7 Urethral discharge Genitourinary 0.865 0.626 – 1.2 0.379 41 285 exclusion phecode
599.8 Other symptoms involving urinary system Genitourinary 1.03 0.971 – 1.09 0.33 1574 4642 exclusion phecode
599.9 Other abnormality of urination Genitourinary 0.954 0.889 – 1.02 0.193 983 4214 exclusion phecode
600 Hyperplasia of prostate Genitourinary 0.978 0.91 – 1.05 0.553 1479 2300 exclusion phecode
601 Inflammatory diseases of prostate Genitourinary 0.967 0.869 – 1.08 0.537 403 2012 exclusion phecode
601.1 Prostatitis Genitourinary 0.931 0.796 – 1.09 0.375 184 1034 exclusion phecode
601.11 Acute prostatitis Genitourinary 1.05 0.762 – 1.43 0.784 45 270 exclusion phecode
601.12 Chronic prostatitis Genitourinary 1.14 0.774 – 1.68 0.507 33 217 exclusion phecode
601.3 Orchitis and epididymitis Genitourinary 1.06 0.882 – 1.28 0.527 150 773 exclusion phecode
601.4 Balanoposthitis Genitourinary 0.952 0.69 – 1.31 0.767 47 238 exclusion phecode
601.8
Other inflammatory disorders of male genital
Other inflammatory disorders of male genital organs
 Genitourinary 1.01 0.784 – 1.3 0.946 69 311 exclusion phecode
602 Other disorders of prostate Genitourinary 0.942 0.775 – 1.14 0.547 115 734 exclusion phecode
602.3 Dysplasia of prostate Genitourinary 0.727 0.474 – 1.12 0.144 22 174 exclusion phecode
603 Other disorders of testis Genitourinary 0.913 0.764 – 1.09 0.313 157 784 exclusion phecode
603.1 Hydrocele Genitourinary 0.899 0.724 – 1.12 0.336 115 552 exclusion phecode
603.2 Spermatocele Genitourinary 0.833 0.627 – 1.11 0.21 59 270 exclusion phecode
604 Disorders of penis Genitourinary 0.92 0.798 – 1.06 0.251 221 1181 exclusion phecode
604.1 Redundant prepuce and phimosis/BXO Genitourinary 1.12 0.847 – 1.49 0.424 52 279 exclusion phecode
604.3 Peyronie's disease Genitourinary 0.828 0.614 – 1.12 0.215 47 361 exclusion phecode
605 Erectile dysfunction [ED] Genitourinary 0.998 0.928 – 1.07 0.948 1325 2135 exclusion phecode
608 Other disorders of male genital organs Genitourinary 1.02 0.927 – 1.12 0.72 595 2271 exclusion phecode
609 Male infertility and abnormal spermatozoa Genitourinary 0.858 0.709 – 1.04 0.112 133 796 exclusion phecode
609.1 Infertility, male Genitourinary 0.811 0.636 – 1.03 0.0909 92 539 exclusion phecode
609.11 Azoospermia and oligospermia Genitourinary 0.723 0.458 – 1.14 0.163 26 168 exclusion phecode
609.2 Abnormal spermatozoa Genitourinary 0.991 0.744 – 1.32 0.953 48 302 exclusion phecode
610 Benign mammary dysplasias Genitourinary 0.894 0.829 – 0.964 0.00359 1011 2371 exclusion phecode
610.1 Cystic mastopathy Genitourinary 0.88 0.793 – 0.976 0.0157 438 1978 exclusion phecode
610.2 Fibroadenosis of breast Genitourinary 0.715 0.44 – 1.16 0.177 25 90 exclusion phecode
610.4 Benign neoplasm of breast Genitourinary 0.909 0.837 – 0.989 0.0257 778 2335 exclusion phecode
610.8 Other specified benign mammary dysplasias Genitourinary 0.856 0.758 – 0.966 0.012 310 1661 exclusion phecode
611 Abnormal findings on mammogram or breast exam Genitourinary 0.921 0.867 – 0.979 0.00815 1907 2962 exclusion phecode
611.1 Abnormal mammogram Genitourinary 0.919 0.86 – 0.983 0.0134 1526 2367 exclusion phecode
611.11 Mammographic microcalcification Genitourinary 0.888 0.793 – 0.996 0.042 381 1477 exclusion phecode
611.3 Lump or mass in breast Genitourinary 0.904 0.842 – 0.971 0.00551 1145 2935 exclusion phecode
612
Breast conditions, congenital or relating to
Breast conditions, congenital or relating to hormones
 Genitourinary 0.879 0.775 – 0.997 0.0443 307 1665 exclusion phecode
612.1 Galactorrhea Genitourinary 1.08 0.772 – 1.52 0.64 45 233 exclusion phecode
612.2 Hypertrophy of breast (Gynecomastia) Genitourinary 0.852 0.737 – 0.985 0.03 226 1259 exclusion phecode
612.3 Congenital anomalies of breast Genitourinary 0.377 0.225 – 0.63 0.000195 30 124 exclusion phecode
613 Other nonmalignant breast conditions Genitourinary 0.966 0.903 – 1.03 0.31 1150 3967 exclusion phecode
613.1 Inflammatory disease of breast Genitourinary 1.02 0.857 – 1.21 0.839 163 1014 exclusion phecode
613.5 Mastodynia Genitourinary 0.913 0.831 – 1 0.0571 553 2939 exclusion phecode
613.7 Other signs and symptoms in breast Genitourinary 0.962 0.844 – 1.1 0.558 283 1583 exclusion phecode
613.8 Other specified disorders of breast Genitourinary 1.06 0.929 – 1.22 0.366 245 1580 exclusion phecode
613.9 Breast disorder NOS Genitourinary 0.918 0.825 – 1.02 0.119 394 2400 exclusion phecode
614 Inflammatory diseases of female pelvic organs Genitourinary 0.928 0.867 – 0.993 0.0316 1206 3285 exclusion phecode
614.1
Pelvic peritoneal adhesions, female
Pelvic peritoneal adhesions, female (postoperative) (postinfection)
 Genitourinary 0.936 0.739 – 1.19 0.588 81 534 exclusion phecode
614.3 Pelvic inflammatory disease (PID) Genitourinary 1.15 0.951 – 1.39 0.15 145 768 exclusion phecode
614.31 Acute inflammatory pelvic disease Genitourinary 1 0.605 – 1.66 0.997 24 139 exclusion phecode
614.32 Chronic inflammatory pelvic disease Genitourinary 1.14 0.817 – 1.58 0.446 54 257 exclusion phecode
614.33 Pelvic inflammatory disease, NOS Genitourinary 1.36 1.06 – 1.76 0.0169 82 406 exclusion phecode
614.4 Inflammatory diseases of uterus, except cervix Genitourinary 0.934 0.696 – 1.26 0.652 56 291 exclusion phecode
614.5
Inflammatory disease of cervix, vagina, and
Inflammatory disease of cervix, vagina, and vulva
 Genitourinary 0.913 0.85 – 0.98 0.0118 1072 3257 exclusion phecode
614.51 Cervicitis and endocervicitis Genitourinary 0.838 0.663 – 1.06 0.139 83 476 exclusion phecode
614.52 Vaginitis and vulvovaginitis Genitourinary 0.908 0.842 – 0.978 0.0112 935 3148 exclusion phecode
614.53 Cyst or abscess of Bartholin's gland Genitourinary 1.04 0.741 – 1.46 0.823 45 266 exclusion phecode
614.54 Abscess or ulceration of vulva Genitourinary 0.842 0.657 – 1.08 0.172 73 423 exclusion phecode
615 Endometriosis Genitourinary 0.971 0.867 – 1.09 0.615 368 2372 exclusion phecode
618 Genital prolapse Genitourinary 0.959 0.869 – 1.06 0.402 459 3293 exclusion phecode
618.1 Prolapse of vaginal walls Genitourinary 0.899 0.793 – 1.02 0.0942 275 2454 exclusion phecode
618.2 Uterine/Uterovaginal prolapse Genitourinary 0.89 0.735 – 1.08 0.232 122 970 exclusion phecode
618.5 Prolapse of vaginal vault after hysterectomy Genitourinary 0.878 0.638 – 1.21 0.423 38 538 exclusion phecode
618.6 Vaginal enterocele, congenital or acquired Genitourinary 1.06 0.861 – 1.3 0.598 108 769 exclusion phecode
619 Noninflammatory female genital disorders Genitourinary 0.922 0.866 – 0.981 0.00976 1639 3064 exclusion phecode
619.1
Noninflammatory disorders of ovary, fallopian
Noninflammatory disorders of ovary, fallopian tube, and broad ligament
 Genitourinary 0.836 0.741 – 0.944 0.00392 340 1890 exclusion phecode
619.2 Disorders of uterus, NEC Genitourinary 0.939 0.798 – 1.1 0.444 178 1004 exclusion phecode
619.3 Noninflammatory disorders of cervix Genitourinary 0.876 0.732 – 1.05 0.145 149 742 exclusion phecode
619.4 Noninflammatory disorders of vagina Genitourinary 0.927 0.855 – 1 0.0652 811 2993 exclusion phecode
619.5 Noninflammatory disorders of vulva and perineum Genitourinary 0.973 0.873 – 1.09 0.63 384 2038 exclusion phecode
620 Dysplasia of female genital organs Genitourinary 0.908 0.741 – 1.11 0.354 115 694 exclusion phecode
620.1 Dysplasia of cervix Genitourinary 0.936 0.703 – 1.25 0.648 62 303 exclusion phecode
621 Endometrial hyperplasia Genitourinary 0.762 0.63 – 0.922 0.0053 131 671 exclusion phecode
622 Polyp of female genital organs Genitourinary 0.901 0.816 – 0.996 0.0425 466 2518 exclusion phecode
622.1 Polyp of corpus uteri Genitourinary 0.918 0.819 – 1.03 0.137 360 1947 exclusion phecode
622.2 Mucous polyp of cervix Genitourinary 0.796 0.664 – 0.953 0.0133 150 783 exclusion phecode
623 Hypertrophy of female genital organs Genitourinary 0.971 0.856 – 1.1 0.646 292 1503 exclusion phecode
624 Symptoms involving female genital tract Genitourinary 0.963 0.865 – 1.07 0.483 450 1952 exclusion phecode
624.1 Dystrophy of female genital tract Genitourinary 0.997 0.768 – 1.29 0.984 66 378 exclusion phecode
624.2 Atrophy of female genital tract Genitourinary 1.08 0.701 – 1.65 0.74 18 133 exclusion phecode
624.9 stress incontinence, female Genitourinary 0.962 0.871 – 1.06 0.442 491 2341 exclusion phecode
625
Pain and other symptoms associated with female
Pain and other symptoms associated with female genital organs
 Genitourinary 0.921 0.865 – 0.981 0.0105 1662 2683 exclusion phecode
625.1 Dyspareunia Genitourinary 0.942 0.834 – 1.06 0.34 322 1786 exclusion phecode
626
Disorders of menstruation and other abnormal
Disorders of menstruation and other abnormal bleeding from female genital tract
 Genitourinary 0.93 0.87 – 0.994 0.0331 1836 2105 exclusion phecode
626.1 Irregular menstrual cycle/bleeding Genitourinary 0.922 0.858 – 0.992 0.0286 1477 1944 exclusion phecode
626.11 Absent or infrequent menstruation Genitourinary 0.963 0.854 – 1.09 0.539 378 1137 exclusion phecode
626.12 Excessive or frequent menstruation Genitourinary 0.877 0.799 – 0.962 0.00539 745 1543 exclusion phecode
626.13 Irregular menstrual cycle Genitourinary 0.897 0.817 – 0.985 0.0234 697 1626 exclusion phecode
626.14 Irregular menstrual bleeding Genitourinary 0.928 0.82 – 1.05 0.233 364 1148 exclusion phecode
626.15 Infertility, female, associated with anovulation Genitourinary 1 0.835 – 1.21 0.975 156 591 exclusion phecode
626.2 Dysmenorrhea Genitourinary 0.965 0.86 – 1.08 0.542 437 1253 exclusion phecode
626.4 Premenstrual tension syndromes Genitourinary 0.887 0.717 – 1.1 0.272 121 469 exclusion phecode
626.8 Infertility, female Genitourinary 1.04 0.907 – 1.2 0.562 285 885 exclusion phecode
627 Menopausal and postmenopausal disorders Genitourinary 0.854 0.796 – 0.917 1.4e-05 1348 1938 exclusion phecode
627.1 Postmenopausal bleeding Genitourinary 0.863 0.765 – 0.973 0.0158 334 1413 exclusion phecode
627.2 Symptomatic menopause Genitourinary 0.862 0.794 – 0.936 0.000397 896 1823 exclusion phecode
627.21 Symptomatic artificial menopause Genitourinary 0.845 0.626 – 1.14 0.27 54 199 exclusion phecode
627.22
Need for Hormone replacement therapy
Need for Hormone replacement therapy (postmenopausal)
 Genitourinary 0.937 0.762 – 1.15 0.538 98 564 exclusion phecode
627.3 Postmenopausal atrophic vaginitis Genitourinary 0.88 0.777 – 0.998 0.0463 303 1325 exclusion phecode
627.4 Premenopausal menorrhagia Genitourinary 0.948 0.78 – 1.15 0.588 131 505 exclusion phecode
627.5 Premature menopause and other ovarian failure Genitourinary 0.747 0.594 – 0.94 0.013 96 428 exclusion phecode
628 Ovarian cyst Genitourinary 0.885 0.804 – 0.975 0.0131 606 1825 exclusion phecode
634 Miscarriage; stillbirth Pregnancy Complications 0.982 0.861 – 1.12 0.786 280 1469 exclusion phecode
634.1 Missed abortion/Hydatidiform mole Pregnancy Complications 0.827 0.658 – 1.04 0.103 99 550 exclusion phecode
634.3 Ectopic pregnancy Pregnancy Complications 0.969 0.678 – 1.38 0.861 36 215 exclusion phecode
635
Hemorrhage during pregnancy; childbirth and
Hemorrhage during pregnancy; childbirth and postpartum
 Pregnancy Complications 1.01 0.866 – 1.18 0.888 199 1002 exclusion phecode
635.2
Antepartum hemorrhage, abruptio placentae, and
Antepartum hemorrhage, abruptio placentae, and placenta previa
 Pregnancy Complications 1.11 0.916 – 1.33 0.296 141 691 exclusion phecode
635.3 Placenta previa and abruptio placenta Pregnancy Complications 0.915 0.736 – 1.14 0.425 94 550 exclusion phecode
636
Early or threatened labor; hemorrhage in early
Early or threatened labor; hemorrhage in early pregnancy
 Pregnancy Complications 1.02 0.905 – 1.15 0.744 378 1470 exclusion phecode
636.1 Threatened premature labor Pregnancy Complications 1.01 0.838 – 1.23 0.882 139 682 exclusion phecode
636.2 Early onset of delivery Pregnancy Complications 0.981 0.8 – 1.2 0.851 119 552 exclusion phecode
636.3 Hemorrhage in early pregnancy Pregnancy Complications 1.16 0.968 – 1.38 0.11 165 825 exclusion phecode
636.8 Cervical incompetence Pregnancy Complications 0.847 0.524 – 1.37 0.499 24 154 exclusion phecode
637
Short gestation; low birth weight; and fetal
Short gestation; low birth weight; and fetal growth retardation
 Pregnancy Complications 1.11 0.76 – 1.62 0.595 33 159 exclusion phecode
642
Hypertension complicating pregnancy
Hypertension complicating pregnancy, childbirth, and the puerperium
 Pregnancy Complications 1.09 0.931 – 1.28 0.277 193 1228 exclusion phecode
642.1 Preeclampsia and eclampsia Pregnancy Complications 1.14 0.916 – 1.42 0.24 109 682 exclusion phecode
643 Excessive vomiting in pregnancy Pregnancy Complications 1.14 0.906 – 1.44 0.262 91 560 exclusion phecode
643.1 Hyperemesis gravidarum Pregnancy Complications 0.991 0.703 – 1.4 0.96 43 257 exclusion phecode
644 Anemia during pregnancy Pregnancy Complications 0.851 0.668 – 1.08 0.191 80 512 exclusion phecode
646 Other complications of pregnancy NEC Pregnancy Complications 1.02 0.892 – 1.18 0.737 269 1266 exclusion phecode
647
Infectious and parasitic complications
Infectious and parasitic complications affecting pregnancy
 Pregnancy Complications 1.09 0.83 – 1.42 0.541 72 488 exclusion phecode
647.1
Infections of genitourinary tract during
Infections of genitourinary tract during pregnancy
 Pregnancy Complications 0.979 0.761 – 1.26 0.867 78 464 exclusion phecode
647.3 Major puerperal infection Pregnancy Complications 0.839 0.519 – 1.36 0.473 18 151 exclusion phecode
649
Other conditions or status of the mother
Other conditions or status of the mother complicating pregnancy, childbirth, or the puerperium
 Pregnancy Complications 1.06 0.948 – 1.19 0.3 424 1499 exclusion phecode
649.1
Diabetes or abnormal glucose tolerance
Diabetes or abnormal glucose tolerance complicating pregnancy
 Pregnancy Complications 0.964 0.842 – 1.1 0.596 263 1303 exclusion phecode
653
Problems associated with amniotic cavity and
Problems associated with amniotic cavity and membranes
 Pregnancy Complications 1.01 0.866 – 1.19 0.862 199 1105 exclusion phecode
654.1
Abnormality of organs and soft tissues of
Abnormality of organs and soft tissues of pelvis complicating pregnancy, childbirth, or the puerperium
 Pregnancy Complications 1.19 0.908 – 1.55 0.212 70 402 exclusion phecode
654.2 Rhesus isoimmunization in pregnancy Pregnancy Complications 1.06 0.818 – 1.38 0.651 76 410 exclusion phecode
655
Known or suspected fetal abnormality affecting
Known or suspected fetal abnormality affecting management of mother
 Pregnancy Complications 1.06 0.955 – 1.17 0.293 547 1875 exclusion phecode
655.1 Abnormality in fetal heart rate or rhythm Pregnancy Complications 1.03 0.889 – 1.2 0.668 225 1051 exclusion phecode
656 Other perinatal conditions of fetus or newborn Pregnancy Complications 1.03 0.904 – 1.17 0.668 300 1362 exclusion phecode
656.2 Respiratory conditions of fetus and newborn Pregnancy Complications 0.867 0.534 – 1.41 0.566 24 143 exclusion phecode
669 Complications of labor and delivery NEC Pregnancy Complications 1.05 0.92 – 1.19 0.483 304 1347 exclusion phecode
671
Venous/cerebrovascular complications embolism
Venous/cerebrovascular complications embolism in pregnancy and the puerperium
 Pregnancy Complications 1.04 0.802 – 1.34 0.789 72 445 exclusion phecode
674 Other complications of the puerperium NEC Pregnancy Complications 0.998 0.727 – 1.37 0.991 49 343 exclusion phecode
676
Other disorders of the breast associated with
Other disorders of the breast associated with childbirth and disorders of lactation
 Pregnancy Complications 1.07 0.83 – 1.37 0.609 83 404 exclusion phecode
681 Superficial cellulitis and abscess Dermatologic 1.01 0.962 – 1.06 0.711 2423 6666 exclusion phecode
681.1 Cellulitis and abscess of fingers/toes Dermatologic 1.03 0.941 – 1.12 0.542 637 2566 exclusion phecode
681.2 Cellulitis and abscess of face/neck Dermatologic 1.05 0.935 – 1.18 0.403 343 1895 exclusion phecode
681.3 Cellulitis and abscess of arm/hand Dermatologic 1.01 0.936 – 1.08 0.886 969 3791 exclusion phecode
681.5 Cellulitis and abscess of leg, except foot Dermatologic 1.03 0.96 – 1.1 0.436 1048 3951 exclusion phecode
681.6 Cellulitis and abscess of foot, toe Dermatologic 1.04 0.969 – 1.13 0.252 867 3321 exclusion phecode
681.7 Cellulitis and abscess of trunk Dermatologic 1.01 0.923 – 1.1 0.857 584 2935 exclusion phecode
686
Other local infections of skin and subcutaneous
Other local infections of skin and subcutaneous tissue
 Dermatologic 1.06 0.984 – 1.14 0.125 872 4006 exclusion phecode
686.1 Carbuncle and furuncle Dermatologic 1.07 0.926 – 1.24 0.347 226 1160 exclusion phecode
686.2 Impetigo Dermatologic 0.959 0.808 – 1.14 0.634 165 827 exclusion phecode
686.3 Pilonidal cyst Dermatologic 1.09 0.816 – 1.46 0.555 55 366 exclusion phecode
686.4 Pyogenic granuloma Dermatologic 0.856 0.621 – 1.18 0.341 49 270 exclusion phecode
686.5 Pyoderma Dermatologic 0.976 0.633 – 1.51 0.914 25 132 exclusion phecode
687 Symptoms affecting skin Dermatologic 0.914 0.841 – 0.994 0.0363 683 2902 exclusion phecode
687.1 Rash and other nonspecific skin eruption Dermatologic 0.956 0.912 – 1 0.0649 2662 5505 exclusion phecode
687.3 Changes in skin texture Dermatologic 1.05 0.897 – 1.22 0.557 194 947 exclusion phecode
687.4 Disturbance of skin sensation Dermatologic 0.944 0.897 – 0.993 0.025 2143 5453 exclusion phecode
689 Disorder of skin and subcutaneous tissue NOS Dermatologic 0.999 0.957 – 1.04 0.981 3310 6350 exclusion phecode
690 Erythematosquamous dermatosis Dermatologic 0.946 0.898 – 0.996 0.0355 2038 5496 exclusion phecode
690.1 Seborrheic dermatitis Dermatologic 0.946 0.899 – 0.997 0.0367 2037 5491 exclusion phecode
691 Congenital anomalies of skin Dermatologic 0.887 0.763 – 1.03 0.121 204 972 exclusion phecode
691.3 Congenital pigmentary anomalies of skin Dermatologic 0.95 0.545 – 1.65 0.855 14 99 exclusion phecode
694 Dyschromia and Vitiligo Dermatologic 0.932 0.857 – 1.01 0.102 661 3213 exclusion phecode
694.1 Vitiligo Dermatologic 1.01 0.762 – 1.33 0.96 54 313 exclusion phecode
694.2 Other dyschromia Dermatologic 0.915 0.836 – 1 0.0532 579 2868 exclusion phecode
694.3 Vascular disorders of skin Dermatologic 1.17 0.812 – 1.69 0.397 40 136 exclusion phecode
695 Erythematous conditions Dermatologic 0.911 0.859 – 0.966 0.00184 1480 5252 exclusion phecode
695.1 Toxic erythema Dermatologic 0.697 0.464 – 1.05 0.0818 25 144 exclusion phecode
695.2 Bullous dermatoses Dermatologic 0.963 0.637 – 1.46 0.859 32 141 exclusion phecode
695.3 Rosacea Dermatologic 0.891 0.819 – 0.97 0.008 643 3142 exclusion phecode
695.4 Lupus (localized and systemic) Dermatologic 1 0.858 – 1.17 0.992 210 1010 exclusion phecode
695.41 Cutaneous lupus erythematosus Dermatologic 0.961 0.761 – 1.21 0.737 89 362 exclusion phecode
695.42 Systemic lupus erythematosus Dermatologic 1 0.853 – 1.18 0.977 195 960 exclusion phecode
695.7 Prurigo and Lichen Dermatologic 0.918 0.789 – 1.07 0.265 210 1113 exclusion phecode
695.8 Other specified erythematous conditions Dermatologic 0.905 0.807 – 1.02 0.0889 358 1531 exclusion phecode
695.81 Erythema nodosum Dermatologic 0.822 0.504 – 1.34 0.431 23 82 exclusion phecode
695.9 Unspecified erythematous condition Dermatologic 0.915 0.802 – 1.04 0.187 266 1310 exclusion phecode
696 Psoriasis and related disorders Dermatologic 0.929 0.839 – 1.03 0.155 432 2464 exclusion phecode
696.3 Pityriasis Dermatologic 0.971 0.665 – 1.42 0.878 28 151 exclusion phecode
696.4 Psoriasis Dermatologic 0.92 0.828 – 1.02 0.125 404 2354 exclusion phecode
696.41 Psoriasis vulgaris Dermatologic 0.914 0.819 – 1.02 0.104 383 2180 exclusion phecode
696.42 Psoriatic arthropathy Dermatologic 0.986 0.789 – 1.23 0.903 90 499 exclusion phecode
697 Sarcoidosis Dermatologic 1.04 0.836 – 1.28 0.743 95 618 exclusion phecode
698 Pruritus and related conditions Dermatologic 0.977 0.907 – 1.05 0.535 859 4437 exclusion phecode
700 Corns and callosities Dermatologic 0.999 0.921 – 1.08 0.982 798 2369 exclusion phecode
701
Other hypertrophic and atrophic conditions of
Other hypertrophic and atrophic conditions of skin
 Dermatologic 0.967 0.923 – 1.01 0.162 2543 6601 exclusion phecode
701.1 Keratoderma, acquired Dermatologic 0.99 0.857 – 1.14 0.891 246 1144 exclusion phecode
701.2 Scar conditions and fibrosis of skin Dermatologic 0.896 0.816 – 0.984 0.0213 522 3590 exclusion phecode
701.3 Circumscribed scleroderma Dermatologic 0.993 0.841 – 1.17 0.931 168 970 exclusion phecode
701.4 Keloid scar Dermatologic 1.03 0.865 – 1.22 0.771 166 1007 exclusion phecode
701.5 Abnormal granulation tissue Dermatologic 0.944 0.773 – 1.15 0.571 120 729 exclusion phecode
702
Degenerative skin conditions and other
Degenerative skin conditions and other dermatoses
 Dermatologic 0.964 0.917 – 1.01 0.158 2633 4726 exclusion phecode
702.1 Actinic keratosis Dermatologic 0.963 0.909 – 1.02 0.204 1653 4703 exclusion phecode
702.2 Seborrheic keratosis Dermatologic 0.951 0.904 – 1 0.0587 2123 5690 exclusion phecode
702.4 Degenerative skin disorders Dermatologic 1.19 0.827 – 1.7 0.354 32 188 exclusion phecode
703 Diseases of nail, NOS Dermatologic 1.04 0.959 – 1.12 0.371 823 3258 exclusion phecode
703.1 Ingrowing nail Dermatologic 0.96 0.868 – 1.06 0.429 459 2072 exclusion phecode
704 Diseases of hair and hair follicles Dermatologic 0.974 0.913 – 1.04 0.415 1140 5585 exclusion phecode
704.1 Alopecia Dermatologic 1.01 0.912 – 1.11 0.894 466 2499 exclusion phecode
704.11 Alopecia Areata Dermatologic 1.23 0.841 – 1.81 0.284 31 165 exclusion phecode
704.12 Telogen effluvium Dermatologic 0.763 0.479 – 1.22 0.255 24 89 exclusion phecode
704.2 Hirsutism Dermatologic 1 0.809 – 1.25 0.965 102 570 exclusion phecode
704.8
Other specified diseases of hair and hair
Other specified diseases of hair and hair follicles
 Dermatologic 0.971 0.895 – 1.05 0.477 699 3629 exclusion phecode
705 Disorders of sweat glands Dermatologic 0.979 0.843 – 1.14 0.783 218 1118 exclusion phecode
705.1 Dyshidrosis Dermatologic 0.901 0.69 – 1.18 0.446 65 290 exclusion phecode
705.3 Hidradenitis Dermatologic 1 0.782 – 1.28 0.987 79 423 exclusion phecode
705.8 Hyperhidrosis Dermatologic 1.05 0.947 – 1.17 0.345 450 2123 exclusion phecode
706 Diseases of sebaceous glands Dermatologic 0.98 0.935 – 1.03 0.404 2355 6941 exclusion phecode
706.1 Acne Dermatologic 0.974 0.905 – 1.05 0.485 956 4030 exclusion phecode
706.2 Sebaceous cyst Dermatologic 0.957 0.896 – 1.02 0.193 1086 4960 exclusion phecode
706.3 Seborrhea Dermatologic 1.09 0.743 – 1.61 0.654 28 121 exclusion phecode
706.8 Other specified diseases of sebaceous glands Dermatologic 0.969 0.896 – 1.05 0.427 783 3173 exclusion phecode
707 Chronic ulcer of skin Dermatologic 1.04 0.975 – 1.11 0.236 1181 5443 exclusion phecode
707.1 Decubitus ulcer Dermatologic 1.12 0.998 – 1.26 0.0543 362 1773 exclusion phecode
707.2 Chronic ulcer of leg or foot Dermatologic 1.06 0.967 – 1.15 0.226 624 2446 exclusion phecode
707.3 Chronic ulcer of unspecified site Dermatologic 1 0.919 – 1.09 0.961 605 3452 exclusion phecode
709 Diffuse diseases of connective tissue Dermatologic 0.951 0.863 – 1.05 0.31 499 2493 exclusion phecode
709.2 Sicca syndrome Dermatologic 0.925 0.781 – 1.1 0.368 164 801 exclusion phecode
709.3 Systemic sclerosis Dermatologic 1.05 0.818 – 1.35 0.695 81 360 exclusion phecode
709.5 Dermatomyositis Dermatologic 0.976 0.659 – 1.44 0.902 34 173 exclusion phecode
709.6
Other specified diffuse diseases of connective
Other specified diffuse diseases of connective tissue
 Dermatologic 0.777 0.54 – 1.12 0.175 34 111 exclusion phecode
709.7 Unspecified diffuse connective tissue disease Dermatologic 0.958 0.85 – 1.08 0.485 321 1627 exclusion phecode
710
Osteomyelitis, periostitis, and other
Osteomyelitis, periostitis, and other infections involving bone
 Musculoskeletal 1.02 0.925 – 1.13 0.665 464 2238 exclusion phecode
710.1 Osteomyelitis Musculoskeletal 1.04 0.94 – 1.15 0.452 453 2162 exclusion phecode
710.11 Acute osteomyelitis Musculoskeletal 0.99 0.866 – 1.13 0.883 274 1196 exclusion phecode
710.12 Chronic osteomyelitis Musculoskeletal 0.979 0.846 – 1.13 0.777 218 1083 exclusion phecode
710.19 Unspecified osteomyelitis Musculoskeletal 1.05 0.945 – 1.16 0.38 430 2084 exclusion phecode
711 Arthropathy associated with infections Musculoskeletal 0.878 0.737 – 1.05 0.145 153 707 exclusion phecode
711.1 Pyogenic arthritis Musculoskeletal 0.97 0.789 – 1.19 0.772 113 515 exclusion phecode
712 Infective connective tissue disorders Musculoskeletal 0.902 0.71 – 1.15 0.397 79 309 exclusion phecode
713
Arthropathy associated with other disorders
Arthropathy associated with other disorders classified elsewhere
 Musculoskeletal 1.15 0.97 – 1.36 0.108 175 827 exclusion phecode
713.5
Arthropathy associated with neurological
Arthropathy associated with neurological disorders
 Musculoskeletal 1.12 0.923 – 1.37 0.246 133 621 exclusion phecode
714
Rheumatoid arthritis and other inflammatory
Rheumatoid arthritis and other inflammatory polyarthropathies
 Musculoskeletal 1 0.917 – 1.09 0.993 652 3231 exclusion phecode
714.1 Rheumatoid arthritis Musculoskeletal 0.965 0.876 – 1.06 0.48 492 2594 exclusion phecode
714.2 Juvenile rheumatoid arthritis Musculoskeletal 1.22 0.814 – 1.84 0.333 23 166 exclusion phecode
715 Other inflammatory spondylopathies Musculoskeletal 0.941 0.845 – 1.05 0.265 423 2084 exclusion phecode
715.1 Sacroiliitis NEC Musculoskeletal 1.06 0.845 – 1.32 0.632 94 448 exclusion phecode
715.2 Ankylosing spondylitis Musculoskeletal 0.829 0.624 – 1.1 0.195 51 378 exclusion phecode
716 Other arthropathies Musculoskeletal 0.972 0.93 – 1.02 0.223 3704 5406 exclusion phecode
716.1 Unspecified polyarthropathy or polyarthritis Musculoskeletal 0.865 0.671 – 1.12 0.264 76 348 exclusion phecode
716.2 Unspecified monoarthritis Musculoskeletal 0.806 0.579 – 1.12 0.201 44 207 exclusion phecode
716.9 Arthropathy NOS Musculoskeletal 0.971 0.928 – 1.02 0.202 3674 5405 exclusion phecode
717 Polymyalgia Rheumatica Musculoskeletal 1.06 0.854 – 1.33 0.579 90 653 exclusion phecode
720 Spinal stenosis Musculoskeletal 0.937 0.88 – 0.999 0.0469 1244 4947 exclusion phecode
720.1 Spinal stenosis of lumbar region Musculoskeletal 0.916 0.853 – 0.985 0.017 965 4132 exclusion phecode
721 Spondylosis and allied disorders Musculoskeletal 0.944 0.894 – 0.996 0.0336 1895 5752 exclusion phecode
721.1 Spondylosis without myelopathy Musculoskeletal 0.942 0.892 – 0.994 0.0308 1801 5681 exclusion phecode
721.2 Spondylosis with myelopathy Musculoskeletal 0.902 0.788 – 1.03 0.132 248 1513 exclusion phecode
721.8 Other allied disorders of spine Musculoskeletal 0.836 0.669 – 1.04 0.114 100 534 exclusion phecode
722 Intervertebral disc disorders Musculoskeletal 0.933 0.885 – 0.984 0.0107 1910 6009 exclusion phecode
722.1 Displacement of intervertebral disc Musculoskeletal 0.931 0.871 – 0.995 0.0347 1084 5472 exclusion phecode
722.3 Schmorl's nodes Musculoskeletal 0.679 0.474 – 0.973 0.035 48 184 exclusion phecode
722.6 Degeneration of intervertebral disc Musculoskeletal 0.937 0.881 – 0.997 0.0391 1309 5423 exclusion phecode
722.7 Intervertebral disc disorder with myelopathy Musculoskeletal 1 0.838 – 1.2 0.962 133 829 exclusion phecode
722.8 Postlaminectomy syndrome Musculoskeletal 1.12 0.917 – 1.37 0.263 112 731 exclusion phecode
722.9 Other and unspecified disc disorder Musculoskeletal 0.925 0.845 – 1.01 0.0859 561 3499 exclusion phecode
723 Other disorders of cervical region Musculoskeletal 0.912 0.806 – 1.03 0.145 309 1688 exclusion phecode
723.1 Torticollis Musculoskeletal 0.867 0.684 – 1.1 0.239 80 450 exclusion phecode
724 Other and unspecified disorders of back Musculoskeletal 0.942 0.887 – 1 0.0516 1373 5691 exclusion phecode
724.1 Disorders of sacrum Musculoskeletal 0.926 0.858 – 0.999 0.0469 820 3945 exclusion phecode
724.2 Disorders of coccyx Musculoskeletal 0.868 0.729 – 1.03 0.109 173 792 exclusion phecode
724.8 Other symptoms referable to back Musculoskeletal 0.883 0.784 – 0.994 0.0395 334 1677 exclusion phecode
724.9 Other unspecified back disorders Musculoskeletal 0.967 0.869 – 1.08 0.538 397 2387 exclusion phecode
726 Peripheral enthesopathies and allied syndromes Musculoskeletal 0.909 0.868 – 0.953 6.61e-05 3469 4264 exclusion phecode
726.1 Enthesopathy Musculoskeletal 0.913 0.868 – 0.961 5e-04 2574 4247 exclusion phecode
726.2 Synoviopathy Musculoskeletal 0.898 0.799 – 1.01 0.0676 361 1468 exclusion phecode
726.3 Bursitis Musculoskeletal 0.906 0.834 – 0.984 0.0195 753 2501 exclusion phecode
726.4 Calcaneal spur; Exostosis NOS Musculoskeletal 0.913 0.818 – 1.02 0.105 421 1729 exclusion phecode
727 Other disorders of synovium, tendon, and bursa Musculoskeletal 0.898 0.853 – 0.945 3.87e-05 2554 4242 exclusion phecode
727.1 Synovitis and tenosynovitis Musculoskeletal 0.894 0.835 – 0.958 0.0014 1146 3539 exclusion phecode
727.2 Bursitis disorders Musculoskeletal 0.885 0.736 – 1.06 0.195 157 632 exclusion phecode
727.4 Ganglion and cyst of synovium, tendon, and bursa Musculoskeletal 0.933 0.846 – 1.03 0.17 498 2040 exclusion phecode
727.5 Rupture of synovium Musculoskeletal 0.895 0.748 – 1.07 0.224 153 652 exclusion phecode
727.6 Rupture of tendon, nontraumatic Musculoskeletal 0.875 0.811 – 0.945 0.000651 872 3042 exclusion phecode
727.7 Contracture of tendon (sheath) Musculoskeletal 0.897 0.754 – 1.07 0.223 156 846 exclusion phecode
727.8 Plica syndrome Musculoskeletal 0.996 0.664 – 1.49 0.986 35 147 exclusion phecode
728 Disorders of muscle, ligament, and fascia Musculoskeletal 0.965 0.909 – 1.03 0.25 1559 4115 exclusion phecode
728.1 Muscular calcification and ossification Musculoskeletal 1.02 0.662 – 1.58 0.916 27 132 exclusion phecode
728.2 Laxity of ligament or hypermobility syndrome Musculoskeletal 0.911 0.727 – 1.14 0.414 100 409 exclusion phecode
728.7 Fasciitis Musculoskeletal 0.931 0.869 – 0.997 0.0409 1095 3372 exclusion phecode
728.71
Contracture of palmar fascia [Dupuytren's
Contracture of palmar fascia [Dupuytren's disease]
 Musculoskeletal 0.884 0.748 – 1.04 0.145 171 765 exclusion phecode
729 Other disorders of soft tissues Musculoskeletal 0.977 0.918 – 1.04 0.468 1390 3823 exclusion phecode
729.1 Rheumatism, unspecified and fibrositis Musculoskeletal 0.799 0.532 – 1.2 0.279 30 116 exclusion phecode
729.3 Panniculitis Musculoskeletal 1.16 0.811 – 1.65 0.419 43 170 exclusion phecode
729.7 Nontraumatic compartment syndrome Musculoskeletal 0.669 0.416 – 1.08 0.0972 19 100 exclusion phecode
731
Osteitis deformans and osteopathies associated
Osteitis deformans and osteopathies associated with other disorders classified elsewhere
 Musculoskeletal 0.995 0.802 – 1.23 0.962 118 540 exclusion phecode
732 Osteochondropathies Musculoskeletal 0.953 0.763 – 1.19 0.671 93 587 exclusion phecode
732.1 Juvenile osteochondrosis Musculoskeletal 0.966 0.734 – 1.27 0.807 58 359 exclusion phecode
732.7 Osteochondritis dissecans Musculoskeletal 0.961 0.601 – 1.54 0.868 28 131 exclusion phecode
733 Other disorders of bone and cartilage Musculoskeletal 0.982 0.924 – 1.04 0.547 1511 4778 exclusion phecode
733.2 Cyst of bone Musculoskeletal 1.19 0.862 – 1.64 0.292 46 321 exclusion phecode
733.4 Aseptic necrosis of bone Musculoskeletal 0.855 0.708 – 1.03 0.105 124 847 exclusion phecode
733.6 Costochondritis Musculoskeletal 1 0.821 – 1.23 0.962 118 625 exclusion phecode
733.8 Malunion and nonunion of fracture Musculoskeletal 1.05 0.896 – 1.24 0.529 163 1288 exclusion phecode
733.9 Chondromalacia Musculoskeletal 1.48 0.873 – 2.51 0.145 16 133 exclusion phecode
735 Acquired foot deformities Musculoskeletal 0.985 0.928 – 1.05 0.613 1362 5729 exclusion phecode
735.1 Flat foot Musculoskeletal 1.09 0.949 – 1.25 0.225 257 1319 exclusion phecode
735.2 Acquired toe deformities Musculoskeletal 0.993 0.909 – 1.08 0.875 617 2701 exclusion phecode
735.21 Hammer toe (acquired) Musculoskeletal 0.991 0.892 – 1.1 0.864 433 1891 exclusion phecode
735.23 Hallux rigidus Musculoskeletal 0.931 0.776 – 1.12 0.446 134 818 exclusion phecode
735.3 Hallux valgus (Bunion) Musculoskeletal 0.877 0.8 – 0.962 0.00532 556 2948 exclusion phecode
736 Other acquired deformities of limbs Musculoskeletal 0.965 0.9 – 1.03 0.318 941 5091 exclusion phecode
736.1 Acquired deformities of forearm Musculoskeletal 0.627 0.406 – 0.968 0.035 31 163 exclusion phecode
736.2 Acquired deformities of finger Musculoskeletal 1.01 0.782 – 1.3 0.951 71 415 exclusion phecode
736.3 Acquired deformities of hip Musculoskeletal 1.32 0.773 – 2.26 0.308 15 89 exclusion phecode
736.4 Genu valgum or varum (acquired) Musculoskeletal 0.898 0.719 – 1.12 0.342 93 559 exclusion phecode
736.5 Acquired deformities of knee Musculoskeletal 0.839 0.652 – 1.08 0.17 70 446 exclusion phecode
736.6 Unequal leg length (acquired) Musculoskeletal 0.916 0.743 – 1.13 0.409 110 592 exclusion phecode
737 Curvature of spine Musculoskeletal 0.963 0.869 – 1.07 0.464 439 2706 exclusion phecode
737.1 Kyphosis (acquired) Musculoskeletal 1.06 0.874 – 1.27 0.577 128 819 exclusion phecode
737.2 Lordosis (acquired) Musculoskeletal 1.05 0.615 – 1.8 0.851 17 120 exclusion phecode
737.3 Kyphoscoliosis and scoliosis Musculoskeletal 0.949 0.845 – 1.06 0.372 339 2030 exclusion phecode
738 Other acquired musculoskeletal deformity Musculoskeletal 0.983 0.901 – 1.07 0.709 574 4223 exclusion phecode
738.4 Acquired spondylolisthesis Musculoskeletal 0.93 0.821 – 1.05 0.255 291 1879 exclusion phecode
739 Contracture of joint Musculoskeletal 0.757 0.644 – 0.89 0.00076 185 1187 exclusion phecode
740 Osteoarthrosis Musculoskeletal 0.947 0.906 – 0.99 0.0156 4442 5120 exclusion phecode
740.1 Osteoarthritis; localized Musculoskeletal 0.934 0.886 – 0.986 0.013 2371 4554 exclusion phecode
740.11 Osteoarthrosis, localized, primary Musculoskeletal 0.923 0.873 – 0.976 0.00459 2111 4391 exclusion phecode
740.12 Osteoarthrosis, localized, secondary Musculoskeletal 0.965 0.828 – 1.12 0.644 217 1170 exclusion phecode
740.2 Osteoarthrosis, generalized Musculoskeletal 0.942 0.858 – 1.03 0.203 659 2000 exclusion phecode
740.3
Osteoarthrosis involving more than one site
Osteoarthrosis involving more than one site, but not specified as generalized
 Musculoskeletal 0.916 0.761 – 1.1 0.353 150 524 exclusion phecode
740.9 Osteoarthrosis NOS Musculoskeletal 0.95 0.909 – 0.994 0.0258 4266 5093 exclusion phecode
741 Symptoms and disorders of the joints Musculoskeletal 0.962 0.919 – 1.01 0.0956 2781 6258 exclusion phecode
741.1 Ankylosis of joint Musculoskeletal 0.929 0.685 – 1.26 0.638 49 373 exclusion phecode
741.2 Stiffness of joint Musculoskeletal 0.967 0.864 – 1.08 0.554 362 2225 exclusion phecode
741.3 Difficulty in walking Musculoskeletal 0.972 0.905 – 1.04 0.43 964 4068 exclusion phecode
741.4 Joint effusions Musculoskeletal 0.983 0.914 – 1.06 0.634 983 4207 exclusion phecode
741.5 Hemarthrosis Musculoskeletal 0.991 0.709 – 1.39 0.96 46 189 exclusion phecode
741.6 Villonodular synovitis Musculoskeletal 0.977 0.595 – 1.61 0.927 22 113 exclusion phecode
742 Derangement of joint, non-traumatic Musculoskeletal 0.92 0.866 – 0.978 0.00747 1349 5821 exclusion phecode
742.1 Loose body in joint Musculoskeletal 0.997 0.695 – 1.43 0.986 35 227 exclusion phecode
742.2
Pathological, developmental or recurrent
Pathological, developmental or recurrent dislocation
 Musculoskeletal 0.933 0.712 – 1.22 0.616 60 393 exclusion phecode
742.8 Articular cartilage disorder Musculoskeletal 0.864 0.658 – 1.13 0.293 61 379 exclusion phecode
742.9 Other derangement of joint Musculoskeletal 0.917 0.862 – 0.977 0.0069 1273 5663 exclusion phecode
743
Osteoporosis, osteopenia and pathological
Osteoporosis, osteopenia and pathological fracture
 Musculoskeletal 0.999 0.953 – 1.05 0.972 2821 6655 exclusion phecode
743.1 Osteoporosis Musculoskeletal 1.02 0.954 – 1.1 0.508 1122 3538 exclusion phecode
743.11 Osteoporosis NOS Musculoskeletal 1.01 0.944 – 1.09 0.707 1103 3501 exclusion phecode
743.12 Senile osteoporosis Musculoskeletal 0.907 0.785 – 1.05 0.186 252 850 exclusion phecode
743.13 Other specified osteoporosis Musculoskeletal 0.966 0.793 – 1.18 0.729 120 521 exclusion phecode
743.2 Pathologic fracture Musculoskeletal 0.935 0.835 – 1.05 0.252 360 1770 exclusion phecode
743.21 Pathologic fracture of vertebrae Musculoskeletal 0.979 0.825 – 1.16 0.803 156 782 exclusion phecode
743.22 Pathologic fracture of femur Musculoskeletal 0.959 0.678 – 1.36 0.812 41 220 exclusion phecode
743.4 Stress fracture Musculoskeletal 0.929 0.79 – 1.09 0.376 170 847 exclusion phecode
743.9
Osteopenia or other disorder of bone and
Osteopenia or other disorder of bone and cartilage
 Musculoskeletal 0.992 0.943 – 1.04 0.757 2300 6345 exclusion phecode
745 Pain in joint Musculoskeletal 0.923 0.884 – 0.963 0.000212 6063 3607 exclusion phecode
747 Cardiac and circulatory congenital anomalies Congenital Anomalies 1.01 0.936 – 1.08 0.861 914 4487 exclusion phecode
747.1 Cardiac congenital anomalies Congenital Anomalies 1.01 0.938 – 1.1 0.723 776 3607 exclusion phecode
747.11 Cardiac shunt/ heart septal defect Congenital Anomalies 0.93 0.813 – 1.06 0.288 282 1284 exclusion phecode
747.12 Valvular heart disease/ heart chambers Congenital Anomalies 1.07 0.952 – 1.19 0.266 391 1587 exclusion phecode
747.13 Congenital anomalies of great vessels Congenital Anomalies 1.24 1.05 – 1.47 0.00969 175 850 exclusion phecode
747.2
Congenital anomalies of peripheral vascular
Congenital anomalies of peripheral vascular system
 Congenital Anomalies 1.06 0.894 – 1.26 0.505 155 956 exclusion phecode
748 Anomalies of respiratory system, congenital Congenital Anomalies 1.08 0.711 – 1.64 0.719 29 224 exclusion phecode
749 Congenital anomalies of face and neck Congenital Anomalies 0.993 0.817 – 1.21 0.945 114 972 exclusion phecode
749.1 Cleft palate Congenital Anomalies 1.22 0.564 – 2.66 0.609 6 122 exclusion phecode
749.2 Congenital anomalies of skull and face bones Congenital Anomalies 0.926 0.572 – 1.5 0.753 20 176 exclusion phecode
750 Digestive congenital anomalies Congenital Anomalies 0.981 0.865 – 1.11 0.762 275 1783 exclusion phecode
750.1 Upper gastrointestinal congenital anomalies Congenital Anomalies 1.01 0.798 – 1.28 0.935 70 682 exclusion phecode
750.11 Esophageal atresia/tracheoesophageal fistula Congenital Anomalies 0.797 0.556 – 1.14 0.215 30 231 exclusion phecode
750.13 Congenital anomalies of mouth/tongue Congenital Anomalies 0.873 0.504 – 1.51 0.628 15 147 exclusion phecode
750.14 Congenital anomalies of esophagus Congenital Anomalies 1.07 0.759 – 1.52 0.685 29 249 exclusion phecode
750.15 Congenital anomalies of stomach Congenital Anomalies 1.43 0.81 – 2.51 0.219 12 110 exclusion phecode
750.2 Lower gastrointestinal congenital anomalies Congenital Anomalies 0.997 0.861 – 1.16 0.971 204 1147 exclusion phecode
750.21 Congenital anomalies of intestine Congenital Anomalies 0.84 0.69 – 1.02 0.0843 110 655 exclusion phecode
750.22
Congenital anomaly of gallbladder, bile ducts
Congenital anomaly of gallbladder, bile ducts, liver, pancreas
 Congenital Anomalies 1.08 0.868 – 1.34 0.5 97 468 exclusion phecode
751 Genitourinary congenital anomalies Congenital Anomalies 0.932 0.856 – 1.01 0.101 646 3888 exclusion phecode
751.1 Congenital anomalies of genital organs Congenital Anomalies 0.965 0.819 – 1.14 0.674 163 1092 exclusion phecode
751.11 Congenital anomalies of female genital organs Congenital Anomalies 0.868 0.709 – 1.06 0.17 110 726 exclusion phecode
751.12 Congenital anomalies of male genital organs Congenital Anomalies 1.05 0.744 – 1.49 0.77 37 312 exclusion phecode
751.2 Congenital anomalies of urinary system Congenital Anomalies 0.931 0.843 – 1.03 0.161 486 2743 exclusion phecode
751.21 Cystic kidney disease Congenital Anomalies 0.917 0.818 – 1.03 0.135 377 1975 exclusion phecode
751.22 Other specified congenital anomalies of kidney Congenital Anomalies 0.85 0.674 – 1.07 0.169 84 584 exclusion phecode
751.3 Obstructive genitourinary defect Congenital Anomalies 1.02 0.729 – 1.44 0.894 35 335 exclusion phecode
752 Nervous system congenital anomalies Congenital Anomalies 0.927 0.817 – 1.05 0.243 275 2152 exclusion phecode
752.1 Neural tube defects Congenital Anomalies 0.907 0.788 – 1.04 0.173 222 1732 exclusion phecode
752.11 Spina bifida Congenital Anomalies 1.05 0.746 – 1.48 0.772 34 316 exclusion phecode
752.2
Other specified congenital anomalies of nervous
Other specified congenital anomalies of nervous system
 Congenital Anomalies 0.979 0.741 – 1.29 0.88 56 435 exclusion phecode
753 Congenital anomalies of the eye Congenital Anomalies 1 0.789 – 1.27 0.999 79 517 exclusion phecode
753.1 Congenital cataract and lens anomalies Congenital Anomalies 0.984 0.621 – 1.56 0.945 23 152 exclusion phecode
753.2 Congenital anomalies of posterior segment of eye Congenital Anomalies 1.15 0.749 – 1.76 0.526 22 142 exclusion phecode
754 Congenital musculoskeletal deformities of spine Congenital Anomalies 0.874 0.779 – 0.982 0.023 339 2345 exclusion phecode
754.1 Lumbosacral spondylolysis, congenital Congenital Anomalies 1.05 0.764 – 1.45 0.757 52 280 exclusion phecode
754.2 Spondylolisthesis, congenital Congenital Anomalies 0.881 0.739 – 1.05 0.159 148 1069 exclusion phecode
755 Congenital anomalies of limbs Congenital Anomalies 0.931 0.809 – 1.07 0.324 218 1518 exclusion phecode
755.1 Congenital deformities of feet Congenital Anomalies 0.924 0.757 – 1.13 0.442 113 775 exclusion phecode
755.4
Congenital anomalies of upper limb, including
Congenital anomalies of upper limb, including shoulder girdle
 Congenital Anomalies 0.985 0.569 – 1.7 0.956 18 140 exclusion phecode
755.6
Other congenital anomalies of lower limb
Other congenital anomalies of lower limb, including pelvic girdle
 Congenital Anomalies 0.91 0.732 – 1.13 0.395 88 579 exclusion phecode
755.61 Congenital hip dysplasia and deformity Congenital Anomalies 1.02 0.757 – 1.36 0.914 47 350 exclusion phecode
756 Other congenital musculoskeletal anomalies Congenital Anomalies 0.907 0.814 – 1.01 0.0779 371 2554 exclusion phecode
756.1 Congenital anomalies of abdominal wall; diaphram Congenital Anomalies 0.836 0.476 – 1.47 0.532 16 116 exclusion phecode
756.2
Pectus and other congenital anomalies of
Pectus and other congenital anomalies of ribs/sternum
 Congenital Anomalies 0.857 0.511 – 1.44 0.56 19 103 exclusion phecode
756.3
Congenital anomalies of muscle, tendon, fascia
Congenital anomalies of muscle, tendon, fascia, and connective tissue
 Congenital Anomalies 0.914 0.74 – 1.13 0.401 94 578 exclusion phecode
756.5 Congenital osteodystrophies Congenital Anomalies 0.954 0.843 – 1.08 0.46 274 1977 exclusion phecode
757 Congenital anomalies of the integument Congenital Anomalies 1.04 0.853 – 1.28 0.679 106 848 exclusion phecode
758 Chromosomal anomalies and genetic disorders Congenital Anomalies 0.96 0.738 – 1.25 0.762 69 396 exclusion phecode
758.1 Chromosomal anomalies Congenital Anomalies 0.987 0.717 – 1.36 0.937 48 298 exclusion phecode
759 Other and unspecified congenital anomalies Congenital Anomalies 1.04 0.875 – 1.22 0.688 158 1067 exclusion phecode
759.1 Anomalies of endocrine glands, congenital Congenital Anomalies 1.11 0.688 – 1.79 0.669 17 150 exclusion phecode
760 Back pain Symptoms 0.948 0.909 – 0.987 0.0103 5007 4666 exclusion phecode
761 Cervicalgia Symptoms 0.954 0.909 – 1 0.0551 2209 7376 exclusion phecode
763
Thoracic or lumbosacral neuritis or
Thoracic or lumbosacral neuritis or radiculitis, unspecified
 Symptoms 0.955 0.897 – 1.02 0.143 1244 5925 exclusion phecode
764 Sciatica Symptoms 0.969 0.911 – 1.03 0.313 1268 5947 exclusion phecode
765 Cervical radiculitis Symptoms 0.973 0.89 – 1.06 0.543 588 3387 exclusion phecode
766 Neuralgia, neuritis, and radiculitis NOS Symptoms 0.957 0.905 – 1.01 0.114 1611 6710 exclusion phecode
767 Cervicocranial/Cervicobrachial syndrome Symptoms 1.12 0.804 – 1.56 0.5 47 255 exclusion phecode
769 Nonallopathic lesions NEC Symptoms 0.949 0.851 – 1.06 0.352 395 2398 exclusion phecode
770 Myalgia and myositis unspecified Symptoms 0.978 0.926 – 1.03 0.416 1692 6734 exclusion phecode
771 Musculoskeletal symptoms referable to limbs Symptoms 0.965 0.913 – 1.02 0.219 1606 5965 exclusion phecode
771.1 Swelling of limb Symptoms 0.977 0.93 – 1.03 0.371 2219 6003 exclusion phecode
771.2 Cramp of limb Symptoms 0.905 0.814 – 1.01 0.0643 430 2058 exclusion phecode
772 Symptoms of the muscles Symptoms 0.967 0.892 – 1.05 0.423 718 3865 exclusion phecode
772.1 Muscular wasting and disuse atrophy Symptoms 1.03 0.847 – 1.25 0.782 126 756 exclusion phecode
772.2 Spasm of muscle Symptoms 0.957 0.885 – 1.04 0.278 740 4223 exclusion phecode
772.3 Muscle weakness Symptoms 1.02 0.95 – 1.09 0.651 1081 5232 exclusion phecode
772.4 Rhabdomyolysis Symptoms 1.09 0.833 – 1.43 0.532 66 314 exclusion phecode
772.6 Facial weakness Symptoms 0.891 0.761 – 1.04 0.151 196 939 exclusion phecode
780 Hypothermia/Chills Symptoms 1.04 0.896 – 1.22 0.578 200 1050 exclusion phecode
781
Symptoms involving nervous and musculoskeletal
Symptoms involving nervous and musculoskeletal systems
 Symptoms 0.974 0.913 – 1.04 0.428 1127 5294 exclusion phecode
781.1 Loss of height Symptoms 0.857 0.656 – 1.12 0.259 61 298 exclusion phecode
781.2 Abnormal posture Symptoms 0.85 0.531 – 1.36 0.5 24 121 exclusion phecode
782.3 Edema Symptoms 1.02 0.971 – 1.07 0.436 2356 6474 exclusion phecode
782.6 Pallor and flushing Symptoms 0.946 0.828 – 1.08 0.409 265 1624 exclusion phecode
783 Fever of unknown origin Symptoms 1.04 0.995 – 1.1 0.0796 2137 7433 exclusion phecode
783.1 Postprocedural fever Symptoms 1.01 0.808 – 1.27 0.899 85 523 exclusion phecode
785 Abdominal pain Symptoms 0.992 0.952 – 1.03 0.696 5240 4431 exclusion phecode
788 Syncope and collapse Symptoms 1.04 0.982 – 1.1 0.182 1525 6931 exclusion phecode
789 Nausea and vomiting Symptoms 1.05 1.01 – 1.1 0.0266 3148 6487 exclusion phecode
789.1 Persistent vomiting Symptoms 1.05 0.923 – 1.2 0.443 271 1389 exclusion phecode
790 Nonspecific findings on examination of blood Symptoms 1.03 0.961 – 1.1 0.413 1067 3880 exclusion phecode
790.1 Elevated sedimentation rate Symptoms 1.01 0.807 – 1.27 0.921 94 413 exclusion phecode
790.6 Other abnormal blood chemistry Symptoms 1.03 0.988 – 1.08 0.153 3143 6106 exclusion phecode
790.8 Elevated C-reactive protein (CRP) Symptoms 0.971 0.789 – 1.19 0.779 112 499 exclusion phecode
790.9 Abnormal arterial blood gases Symptoms 1.05 0.798 – 1.39 0.713 62 263 exclusion phecode
791 Gangrene Symptoms 1.07 0.894 – 1.28 0.452 153 748 exclusion phecode
792
Abnormal Papanicolaou smear of cervix and
Abnormal Papanicolaou smear of cervix and cervical HPV
 Genitourinary 0.94 0.866 – 1.02 0.144 815 2438 exclusion phecode
792.1
Papanicolaou smear of cervix or vagina with
Papanicolaou smear of cervix or vagina with atypical squamous cells
 Genitourinary 1 0.885 – 1.13 0.985 344 1547 exclusion phecode
794
Abnormal results of other function studies
Abnormal results of other function studies (bladder, pancreas, placenta, spleen, etc)
 Symptoms 1 0.816 – 1.23 0.972 106 1006 exclusion phecode
795
Other and nonspecific abnormal cytological
Other and nonspecific abnormal cytological, histological and immunological findings
 Symptoms 1.06 0.969 – 1.15 0.211 606 3797 exclusion phecode
795.8 Abnormal tumor markers Symptoms 0.964 0.873 – 1.06 0.462 458 3468 exclusion phecode
795.81 Elevated carcinoembryonic antigen [CEA] Symptoms 1.1 0.669 – 1.79 0.717 15 131 exclusion phecode
795.82 Elevated cancer antigen 125 [CA 125] Symptoms 0.878 0.621 – 1.24 0.459 37 339 exclusion phecode
796 Elevated prostate specific antigen [PSA] Genitourinary 0.935 0.85 – 1.03 0.163 616 2005 exclusion phecode
797 Shock Symptoms 1.05 0.93 – 1.2 0.407 301 1358 exclusion phecode
797.1 Cardiogenic shock Symptoms 1.06 0.879 – 1.27 0.561 156 599 exclusion phecode
798 Malaise and fatigue Symptoms 1.03 0.991 – 1.08 0.13 4173 5496 exclusion phecode
798.1 Chronic fatigue syndrome Symptoms 1.03 0.947 – 1.12 0.485 700 2949 exclusion phecode
800 Fracture of lower limb Injuries & Poisonings 0.947 0.873 – 1.03 0.19 694 4223 exclusion phecode
800.1 Fracture of neck of femur Injuries & Poisonings 0.918 0.782 – 1.08 0.299 178 962 exclusion phecode
800.2 Fracture of unspecified part of femur Injuries & Poisonings 0.969 0.831 – 1.13 0.692 196 1206 exclusion phecode
800.3 Fracture of tibia and fibula Injuries & Poisonings 1.01 0.887 – 1.16 0.844 252 1568 exclusion phecode
800.4 Fracture of patella Injuries & Poisonings 0.927 0.76 – 1.13 0.456 113 622 exclusion phecode
801 Fracture of ankle and foot Injuries & Poisonings 0.955 0.887 – 1.03 0.222 861 4449 exclusion phecode
801.1 Fracture of foot Injuries & Poisonings 0.977 0.871 – 1.09 0.686 339 2087 exclusion phecode
802 Fracture of pelvis Injuries & Poisonings 1.05 0.849 – 1.29 0.672 102 648 exclusion phecode
803 Fracture of upper limb Injuries & Poisonings 0.886 0.813 – 0.967 0.00633 594 3705 exclusion phecode
803.1 Fracture of humerus Injuries & Poisonings 0.959 0.828 – 1.11 0.581 213 1283 exclusion phecode
803.2 Fracture of radius and ulna Injuries & Poisonings 0.874 0.778 – 0.98 0.0216 334 2042 exclusion phecode
803.21 Colles' fracture Injuries & Poisonings 0.729 0.581 – 0.914 0.00619 87 520 exclusion phecode
803.3 Fracture of clavicle or scapula Injuries & Poisonings 0.87 0.724 – 1.05 0.138 134 903 exclusion phecode
804 Fracture of hand or wrist Injuries & Poisonings 0.915 0.831 – 1.01 0.0665 516 3008 exclusion phecode
805
Fracture of vertebral column without mention of
Fracture of vertebral column without mention of spinal cord injury
 Injuries & Poisonings 1.04 0.932 – 1.15 0.503 398 2379 exclusion phecode
807 Fracture of ribs Injuries & Poisonings 1.03 0.9 – 1.17 0.696 262 1352 exclusion phecode
809 Fracture of unspecified bones Injuries & Poisonings 0.934 0.867 – 1.01 0.0698 839 5265 exclusion phecode
816 Cerebral laceration and contusion Injuries & Poisonings 0.885 0.536 – 1.46 0.632 17 109 exclusion phecode
817 Concussion Injuries & Poisonings 1.01 0.896 – 1.13 0.916 353 2066 exclusion phecode
818 Intracranial hemorrhage (injury) Injuries & Poisonings 0.867 0.716 – 1.05 0.144 119 728 exclusion phecode
818.1 Subdural hemorrhage (injury) Injuries & Poisonings 0.698 0.485 – 1 0.0522 32 199 exclusion phecode
818.2 Subarachnoid hemorrhage (injury) Injuries & Poisonings 1.09 0.745 – 1.6 0.65 32 244 exclusion phecode
819
Skull and face fracture and other intercranial
Skull and face fracture and other intercranial injury
 Injuries & Poisonings 1.02 0.937 – 1.11 0.679 671 4482 exclusion phecode
830 Dislocation Injuries & Poisonings 0.98 0.919 – 1.04 0.536 1115 6642 exclusion phecode
835 Internal derangement of knee Injuries & Poisonings 0.941 0.868 – 1.02 0.142 711 4300 exclusion phecode
836 Traumatic arthropathy Injuries & Poisonings 0.899 0.749 – 1.08 0.253 148 908 exclusion phecode
840 Sprains and strains Injuries & Poisonings 0.929 0.887 – 0.973 0.00189 2569 6735 exclusion phecode
840.1 Muscle/tendon sprain Injuries & Poisonings 0.884 0.755 – 1.03 0.124 199 985 exclusion phecode
840.2 Rotator cuff (capsule) sprain Injuries & Poisonings 0.892 0.816 – 0.976 0.0131 574 3052 exclusion phecode
840.3 Joint/ligament sprain Injuries & Poisonings 0.873 0.81 – 0.941 0.000386 858 4465 exclusion phecode
841 Sprains and strains of back and neck Injuries & Poisonings 0.824 0.754 – 0.899 1.4e-05 647 3056 exclusion phecode
842 Other sprains and strains Injuries & Poisonings 0.931 0.845 – 1.03 0.148 499 2574 exclusion phecode
850 Hemorrhage or hematoma complicating a procedure Injuries & Poisonings 1.05 0.969 – 1.15 0.22 648 3586 exclusion phecode
851
Complications of transplants and reattached
Complications of transplants and reattached limbs
 Injuries & Poisonings 1.06 0.995 – 1.14 0.0692 1087 4834 exclusion phecode
853 Complication of colostomy or enterostomy Injuries & Poisonings 1.14 0.938 – 1.38 0.193 132 681 exclusion phecode
854
Complications of cardiac/vascular device
Complications of cardiac/vascular device, implant, and graft
 Injuries & Poisonings 1.15 1.06 – 1.23 0.000341 895 3683 exclusion phecode
855
Complication of nervous system device, implant
Complication of nervous system device, implant, and graft
 Injuries & Poisonings 1.51 1.09 – 2.1 0.0135 47 417 exclusion phecode
856
Vascular complications of surgery and medical
Vascular complications of surgery and medical procedures
 Injuries & Poisonings 1.21 0.984 – 1.5 0.0699 121 513 exclusion phecode
857
Mechanical complication of unspecified
Mechanical complication of unspecified genitourinary device, implant, and graft
 Injuries & Poisonings 1.03 0.919 – 1.15 0.613 359 2342 exclusion phecode
858 Complication of internal orthopedic device Injuries & Poisonings 1.04 0.943 – 1.15 0.41 442 3458 exclusion phecode
859
Complication due to other implant and internal
Complication due to other implant and internal device
 Injuries & Poisonings 1.09 0.995 – 1.2 0.0624 532 3638 exclusion phecode
860 Bone marrow or stem cell transplant Neoplasms 0.958 0.739 – 1.24 0.745 68 403 exclusion phecode
870 Open wounds of head; neck; and trunk Injuries & Poisonings 1.04 0.978 – 1.1 0.218 1258 6694 exclusion phecode
870.1 Open wound or laceration of eye or eyelid Injuries & Poisonings 1.2 0.922 – 1.55 0.178 64 432 exclusion phecode
870.2 Open wound of ear Injuries & Poisonings 0.999 0.726 – 1.37 0.994 45 251 exclusion phecode
870.3 Other open wound of head and face Injuries & Poisonings 0.909 0.815 – 1.01 0.0858 385 2549 exclusion phecode
870.4 Open wound of nose and sinus Injuries & Poisonings 0.783 0.572 – 1.07 0.128 41 368 exclusion phecode
870.5 Open wound of lip and mouth Injuries & Poisonings 0.994 0.751 – 1.32 0.965 58 482 exclusion phecode
870.6 Open wound of neck Injuries & Poisonings 0.712 0.487 – 1.04 0.078 33 362 exclusion phecode
870.8 Open wound of genital organs Injuries & Poisonings 1.44 0.975 – 2.14 0.0666 28 267 exclusion phecode
871 Open wounds of extremities Injuries & Poisonings 0.986 0.928 – 1.05 0.641 1288 6257 exclusion phecode
871.1 Open wound of hand except finger(s) Injuries & Poisonings 1.03 0.876 – 1.21 0.734 190 1106 exclusion phecode
871.2 Open wound of finger(s) Injuries & Poisonings 0.991 0.886 – 1.11 0.882 369 2169 exclusion phecode
871.3 Open wound of foot except toe(s) alone Injuries & Poisonings 1.02 0.891 – 1.18 0.742 253 1255 exclusion phecode
871.4 Open wound of toe(s) Injuries & Poisonings 1.02 0.861 – 1.21 0.822 171 860 exclusion phecode
872 Traumatic amputation Injuries & Poisonings 0.994 0.86 – 1.15 0.931 230 1228 exclusion phecode
874 Complication of amputation stump Injuries & Poisonings 0.874 0.681 – 1.12 0.287 83 384 exclusion phecode
875 Non-healing surgical wound Injuries & Poisonings 0.945 0.792 – 1.13 0.532 164 1017 exclusion phecode
876
Posttraumatic wound infection not elsewhere
Posttraumatic wound infection not elsewhere classified
 Injuries & Poisonings 1.07 0.943 – 1.21 0.296 287 1574 exclusion phecode
907 Injuries to the nervous system Injuries & Poisonings 0.946 0.821 – 1.09 0.442 219 1928 exclusion phecode
910 Superficial injury, infected Injuries & Poisonings 1.18 0.891 – 1.58 0.244 61 271 exclusion phecode
911 Blister Injuries & Poisonings 0.914 0.775 – 1.08 0.289 170 927 exclusion phecode
912 Insect bite Injuries & Poisonings 0.81 0.696 – 0.943 0.0064 205 1157 exclusion phecode
913 Toxic effect of venom Injuries & Poisonings 0.833 0.692 – 1 0.0549 144 743 exclusion phecode
916 Contusion Injuries & Poisonings 0.966 0.916 – 1.02 0.207 1729 7132 exclusion phecode
930 Allergic reaction to food Injuries & Poisonings 0.878 0.769 – 1 0.0532 279 1161 exclusion phecode
931
Contact dermatitis and other eczema due to
Contact dermatitis and other eczema due to plants [except food]
 Dermatologic 0.827 0.719 – 0.951 0.00759 239 1217 exclusion phecode
938 Dermatitis due to solar radiation Dermatologic 0.954 0.904 – 1.01 0.0875 2085 4391 exclusion phecode
938.1 Acute dermatitis due to solar radiation Dermatologic 0.811 0.631 – 1.04 0.1 80 329 exclusion phecode
938.2 Chronic dermatitis due to solar radiation Dermatologic 0.954 0.904 – 1.01 0.0936 2009 4330 exclusion phecode
939
Atopic/contact dermatitis due to other or
Atopic/contact dermatitis due to other or unspecified
 Dermatologic 0.971 0.924 – 1.02 0.246 2549 4785 exclusion phecode
939.1 Contact and allergic dermatitis of eyelid Dermatologic 1.05 0.724 – 1.51 0.814 35 159 exclusion phecode
941 Adverse reaction to serum or vaccine Injuries & Poisonings 1.24 0.952 – 1.62 0.11 75 324 exclusion phecode
942 Infusion and transfusion reaction Injuries & Poisonings 1.11 0.893 – 1.38 0.35 114 425 exclusion phecode
946 Anaphylactic shock NOS Injuries & Poisonings 0.835 0.711 – 0.98 0.0274 195 874 exclusion phecode
947 Urticaria Dermatologic 0.941 0.843 – 1.05 0.281 401 1826 exclusion phecode
949 Allergies, other Injuries & Poisonings 0.974 0.926 – 1.02 0.303 2455 4784 exclusion phecode
952
Spinal cord injury without evidence of spinal
Spinal cord injury without evidence of spinal bone injury
 Injuries & Poisonings 0.992 0.811 – 1.21 0.94 114 973 exclusion phecode
957 Injury to other and unspecified nerves Injuries & Poisonings 0.619 0.401 – 0.956 0.0304 25 242 exclusion phecode
958
Certain early complications of trauma or
Certain early complications of trauma or procedure
 Injuries & Poisonings 1.05 0.937 – 1.17 0.427 369 2396 exclusion phecode
958.1 Postoperative shock Injuries & Poisonings 1.16 0.89 – 1.51 0.273 74 339 exclusion phecode
958.2 Traumatic and surgical subcutaneous emphysema Injuries & Poisonings 1.15 0.775 – 1.72 0.481 28 239 exclusion phecode
960 Poisoning by antibiotics Injuries & Poisonings 0.999 0.924 – 1.08 0.982 776 3940 exclusion phecode
960.1
Adverse effects of antibacterials (not
Adverse effects of antibacterials (not penicillins)
 Injuries & Poisonings 1.01 0.847 – 1.21 0.89 143 692 exclusion phecode
960.2 Allergy/adverse effect of penicillin Injuries & Poisonings 1.02 0.928 – 1.13 0.643 490 2760 exclusion phecode
961 Poisoning by other anti-infectives Injuries & Poisonings 1.03 0.879 – 1.21 0.703 196 913 exclusion phecode
961.1 Poisoning/allergy of sulfonamides Injuries & Poisonings 0.975 0.865 – 1.1 0.674 320 1810 exclusion phecode
962 Poisoning by hormones and synthetic substitutes Injuries & Poisonings 1.02 0.904 – 1.14 0.798 358 1711 exclusion phecode
962.1
Adrenal cortical steroids causing adverse
Adrenal cortical steroids causing adverse effects in therapeutic use
 Injuries & Poisonings 0.974 0.822 – 1.15 0.763 178 770 exclusion phecode
962.2
Insulins and antidiabetic agents causing
Insulins and antidiabetic agents causing adverse effects in therapeutic use
 Injuries & Poisonings 0.987 0.705 – 1.38 0.938 41 226 exclusion phecode
962.3
Hormones and synthetic substitutes causing
Hormones and synthetic substitutes causing adverse effects in therapeutic use
 Injuries & Poisonings 1.15 0.985 – 1.35 0.0774 194 1032 exclusion phecode
963 Poisoning by primarily systemic agents Injuries & Poisonings 1.03 0.947 – 1.11 0.529 728 4057 exclusion phecode
963.1
Antineoplastic and immunosuppressive drugs
Antineoplastic and immunosuppressive drugs causing adverse effects
 Injuries & Poisonings 1.05 0.965 – 1.14 0.271 702 3964 exclusion phecode
964
Poisoning by agents primarily affecting blood
Poisoning by agents primarily affecting blood constituents
 Injuries & Poisonings 1.02 0.912 – 1.14 0.712 379 1547 exclusion phecode
964.1 Anticoagulants causing adverse effects Injuries & Poisonings 0.998 0.89 – 1.12 0.976 362 1482 exclusion phecode
965
Poisoning by analgesics, antipyretics, and
Poisoning by analgesics, antipyretics, and antirheumatics
 Injuries & Poisonings 1.11 0.975 – 1.26 0.117 297 1465 exclusion phecode
965.1
Opiates and related narcotics causing adverse
Opiates and related narcotics causing adverse effects in therapeutic use
 Injuries & Poisonings 1.06 0.953 – 1.17 0.295 454 2386 exclusion phecode
965.3
Salicylates causing adverse effects in
Salicylates causing adverse effects in therapeutic use
 Injuries & Poisonings 0.921 0.654 – 1.3 0.638 33 207 exclusion phecode
966
Poisoning by anticonvulsants and
Poisoning by anticonvulsants and anti-Parkinsonism drugs
 Injuries & Poisonings 0.749 0.519 – 1.08 0.125 29 187 exclusion phecode
967
Adverse effects of sedatives or other central
Adverse effects of sedatives or other central nervous system depressants and anesthetics
 Injuries & Poisonings 0.977 0.869 – 1.1 0.698 328 2129 exclusion phecode
969 Poisoning by psychotropic agents Injuries & Poisonings 1.11 0.889 – 1.4 0.346 110 471 exclusion phecode
971
Poisoning by drugs primarily affecting the
Poisoning by drugs primarily affecting the autonomic nervous system
 Injuries & Poisonings 0.727 0.475 – 1.11 0.143 37 162 exclusion phecode
972
Poisoning by agents primarily affecting the
Poisoning by agents primarily affecting the cardiovascular system
 Injuries & Poisonings 0.958 0.801 – 1.15 0.637 157 615 exclusion phecode
972.1
Cardiac rhythm regulators causing adverse
Cardiac rhythm regulators causing adverse effects in therapeutic use
 Injuries & Poisonings 0.919 0.649 – 1.3 0.631 46 166 exclusion phecode
972.6 Antihypertensive agents causing adverse effects Injuries & Poisonings 1.04 0.782 – 1.38 0.795 67 219 exclusion phecode
974
Poisoning by water, mineral, and uric acid
Poisoning by water, mineral, and uric acid metabolism drugs
 Injuries & Poisonings 0.975 0.732 – 1.3 0.864 68 275 exclusion phecode
975
Poisoning by agents primarily acting on the
Poisoning by agents primarily acting on the smooth and skeletal muscles and respiratory system
 Injuries & Poisonings 0.807 0.542 – 1.2 0.294 32 135 exclusion phecode
976
Poisoning by agents primarily affecting skin &
Poisoning by agents primarily affecting skin & mucous membrane, ophthalmological, otorhinolaryngological, & dental drugs
 Injuries & Poisonings 1.07 0.747 – 1.54 0.704 30 138 exclusion phecode
977 Personal history of allergy to medicinal agents Injuries & Poisonings 0.999 0.914 – 1.09 0.989 615 2916 exclusion phecode
979 Adverse drug events and drug allergies Injuries & Poisonings 1.02 0.958 – 1.09 0.545 1234 5603 exclusion phecode
980
Encounter for long-term (current) use of
Encounter for long-term (current) use of antibiotics
 Infectious Diseases 1.01 0.915 – 1.12 0.813 422 3000 exclusion phecode
985 Toxic effect of other metals Injuries & Poisonings 1.22 0.733 – 2.04 0.441 19 129 exclusion phecode
989
Toxic effect of other substances, chiefly
Toxic effect of other substances, chiefly nonmedicinal as to source
 Injuries & Poisonings 0.888 0.657 – 1.2 0.44 48 333 exclusion phecode
990 Effects radiation NOS Injuries & Poisonings 1.03 0.958 – 1.12 0.384 755 5841 exclusion phecode
994 Sepsis and SIRS Injuries & Poisonings 1.06 0.985 – 1.14 0.121 883 4532 exclusion phecode
994.1 Systemic inflammatory response syndrome (SIRS) Injuries & Poisonings 1.11 0.912 – 1.35 0.303 120 633 exclusion phecode
994.2 Sepsis Injuries & Poisonings 1.05 0.975 – 1.13 0.195 849 4334 exclusion phecode
994.21 Septic shock Injuries & Poisonings 1.1 0.971 – 1.25 0.136 295 1278 exclusion phecode
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