Plot overview
Signal overview
The plot gives a quick view of the currently visible associations. Click a point to pin its details, inspect that phecode across scans when both rows exist, or open the matching phecode detail page.
Evaluation cohort: Michigan Genomics Initiative Freeze 3 (MGI).
This page pairs the PheWAS plot with the full sortable table for the all-subject and exclusion scans.
Read the all-subject and exclusion scans separately. The combined view is only a browsing aid, and the selected-phecode panel below is only meaningful when the same phecode exists in both scans.
ExPRS exclusion definition
Exclusion cohort: individuals without Current smoker.
For this ExPRS, the exclusion sensitivity scan removes individuals with the exposure itself before rerunning the PheWAS. This is an exposure-based sensitivity analysis rather than a diagnosis-based exclusion.
Plot overview
The plot gives a quick view of the currently visible associations. Click a point to pin its details, inspect that phecode across scans when both rows exist, or open the matching phecode detail page.
| Phecode | Description | Category | OR | 95% CI | P value | Cases | Controls | Analysis | Link |
|---|---|---|---|---|---|---|---|---|---|
| 008 | Intestinal infection | Infectious Diseases | 0.988 | 0.95 – 1.03 | 0.528 | 3004 | 29292 | all | phecode |
| 008.5 | Bacterial enteritis | Infectious Diseases | 1.01 | 0.958 – 1.07 | 0.62 | 1322 | 13162 | all | phecode |
| 008.52 | Intestinal infection due to C. difficile | Infectious Diseases | 1.02 | 0.954 – 1.09 | 0.595 | 1046 | 10455 | all | phecode |
| 008.6 | Viral Enteritis | Infectious Diseases | 1.03 | 0.955 – 1.11 | 0.439 | 770 | 7676 | all | phecode |
| 010 | Tuberculosis | Infectious Diseases | 1.09 | 0.956 – 1.25 | 0.193 | 244 | 2425 | all | phecode |
| 031 | Diseases due to other mycobacteria | Infectious Diseases | 0.981 | 0.784 – 1.23 | 0.866 | 86 | 855 | all | phecode |
| 038 | Septicemia | Infectious Diseases | 1.06 | 1.01 – 1.1 | 0.00991 | 2582 | 24779 | all | phecode |
| 038.1 | Gram negative septicemia | Infectious Diseases | 0.988 | 0.904 – 1.08 | 0.788 | 568 | 5629 | all | phecode |
| 038.2 | Gram positive septicemia | Infectious Diseases | 1.07 | 0.935 – 1.23 | 0.319 | 235 | 2350 | all | phecode |
| 038.3 | Bacteremia | Infectious Diseases | 1.06 | 0.998 – 1.13 | 0.0589 | 1210 | 12079 | all | phecode |
| 041 | Bacterial infection NOS | Infectious Diseases | 1.08 | 1.05 – 1.11 | 3.8e-08 | 5750 | 38799 | all | phecode |
| 041.1 | Staphylococcus infections | Infectious Diseases | 1.1 | 1.05 – 1.16 | 0.000127 | 1707 | 16977 | all | phecode |
| 041.11 | Methicillin sensitive Staphylococcus aureus | Infectious Diseases | 1.08 | 1 – 1.15 | 0.0377 | 920 | 9192 | all | phecode |
| 041.12 | Methicillin resistant Staphylococcus aureus | Infectious Diseases | 1.12 | 1.04 – 1.21 | 0.0023 | 783 | 7812 | all | phecode |
| 041.2 | Streptococcus infection | Infectious Diseases | 1.08 | 1.02 – 1.14 | 0.0046 | 1632 | 16287 | all | phecode |
| 041.21 | Rheumatic fever / chorea | Infectious Diseases | 1.03 | 0.906 – 1.18 | 0.613 | 257 | 2554 | all | phecode |
| 041.4 | E. coli | Infectious Diseases | 1.12 | 1.05 – 1.19 | 0.000441 | 1175 | 11680 | all | phecode |
| 041.8 | H. pylori | Infectious Diseases | 1.05 | 0.919 – 1.19 | 0.483 | 257 | 2521 | all | phecode |
| 041.9 | Infection with drug-resistant microorganisms | Infectious Diseases | 1.1 | 0.985 – 1.22 | 0.0927 | 387 | 3864 | all | phecode |
| 053 | Herpes zoster | Infectious Diseases | 0.982 | 0.93 – 1.04 | 0.514 | 1560 | 15184 | all | phecode |
| 053.1 | Herpes zoster with nervous system complications | Infectious Diseases | 0.905 | 0.786 – 1.04 | 0.164 | 220 | 2169 | all | phecode |
| 054 | Herpes simplex | Infectious Diseases | 0.967 | 0.917 – 1.02 | 0.217 | 1593 | 15600 | all | phecode |
| 070 | Viral hepatitis | Infectious Diseases | 1.18 | 1.1 – 1.27 | 9.7e-06 | 829 | 8280 | all | phecode |
| 070.1 | Viral hepatitis A | Infectious Diseases | 1.01 | 0.804 – 1.27 | 0.936 | 87 | 860 | all | phecode |
| 070.2 | Viral hepatitis B | Infectious Diseases | 1.06 | 0.921 – 1.23 | 0.4 | 215 | 2138 | all | phecode |
| 070.3 | Viral hepatitis C | Infectious Diseases | 1.32 | 1.2 – 1.44 | 6.43e-09 | 528 | 5280 | all | phecode |
| 070.4 | Chronic hepatitis | Infectious Diseases | 0.965 | 0.83 – 1.12 | 0.643 | 197 | 1964 | all | phecode |
| 070.9 | Hepatitis NOS | Infectious Diseases | 1.08 | 1.01 – 1.15 | 0.0162 | 1145 | 11381 | all | phecode |
| 071 | Human immunodeficiency virus [HIV] disease | Infectious Diseases | 1.1 | 0.924 – 1.31 | 0.278 | 145 | 1450 | all | phecode |
| 071.1 | HIV infection, symptomatic | Infectious Diseases | 1.01 | 0.831 – 1.23 | 0.927 | 117 | 1163 | all | phecode |
| 078 | Viral warts & HPV | Infectious Diseases | 0.955 | 0.921 – 0.99 | 0.0123 | 3434 | 29624 | all | phecode |
| 079 | Viral infection | Infectious Diseases | 0.971 | 0.946 – 0.998 | 0.0359 | 6664 | 35342 | all | phecode |
| 079.1 | Varicella infection | Infectious Diseases | 0.926 | 0.894 – 0.959 | 1.5e-05 | 3793 | 31251 | all | phecode |
| 079.2 | Infectious mononucleosis | Infectious Diseases | 1.01 | 0.892 – 1.15 | 0.862 | 283 | 2723 | all | phecode |
| 079.9 | Viremia, NOS | Infectious Diseases | 1.01 | 0.939 – 1.09 | 0.773 | 838 | 8253 | all | phecode |
| 080 | Postoperative infection | Infectious Diseases | 1.08 | 1.04 – 1.13 | 0.000223 | 2619 | 26065 | all | phecode |
| 081 |
Infection/inflammation of internal prostheticInfection/inflammation of internal prosthetic device; implant; and graft
|
Infectious Diseases | 1.03 | 0.979 – 1.09 | 0.238 | 1589 | 15884 | all | phecode |
| 090 |
Sexually transmitted infections (not HIV orSexually transmitted infections (not HIV or hepatitis)
|
Infectious Diseases | 1.03 | 0.96 – 1.1 | 0.428 | 965 | 9630 | all | phecode |
| 110 | Dermatophytosis / Dermatomycosis | Infectious Diseases | 0.99 | 0.954 – 1.03 | 0.583 | 3544 | 30054 | all | phecode |
| 110.1 | Dermatophytosis | Infectious Diseases | 0.984 | 0.947 – 1.02 | 0.407 | 3241 | 27244 | all | phecode |
| 110.11 | Dermatophytosis of nail | Infectious Diseases | 0.998 | 0.952 – 1.05 | 0.947 | 2044 | 16765 | all | phecode |
| 110.12 | Althete's foot | Infectious Diseases | 0.973 | 0.906 – 1.04 | 0.449 | 899 | 8043 | all | phecode |
| 110.13 | Dermatophytosis of the body | Infectious Diseases | 0.96 | 0.891 – 1.04 | 0.29 | 790 | 7827 | all | phecode |
| 110.2 | Dermatomycoses | Infectious Diseases | 1 | 0.902 – 1.12 | 0.944 | 398 | 3971 | all | phecode |
| 112 | Candidiasis | Infectious Diseases | 1.04 | 1 – 1.07 | 0.0468 | 3685 | 30495 | all | phecode |
| 112.3 | Candidiasis of skin and nails | Infectious Diseases | 1.06 | 0.977 – 1.15 | 0.161 | 682 | 6732 | all | phecode |
| 117 | Mycoses | Infectious Diseases | 1.05 | 0.966 – 1.14 | 0.252 | 608 | 6069 | all | phecode |
| 117.1 | Histoplasmosis | Infectious Diseases | 1.21 | 0.965 – 1.51 | 0.0996 | 81 | 801 | all | phecode |
| 117.4 | Aspergillosis | Infectious Diseases | 1.07 | 0.905 – 1.27 | 0.417 | 140 | 1387 | all | phecode |
| 130 | Spirochetal infection | Infectious Diseases | 0.877 | 0.745 – 1.03 | 0.113 | 168 | 1677 | all | phecode |
| 130.1 | Lyme disease | Infectious Diseases | 0.819 | 0.673 – 0.996 | 0.0452 | 116 | 1160 | all | phecode |
| 131 | Protozoan infection | Infectious Diseases | 1.18 | 0.911 – 1.53 | 0.21 | 61 | 610 | all | phecode |
| 132 | Infestation (lice, mites) | Infectious Diseases | 1.13 | 0.977 – 1.31 | 0.0994 | 195 | 1948 | all | phecode |
| 134 | Helminthiases | Infectious Diseases | 1.02 | 0.812 – 1.28 | 0.855 | 83 | 812 | all | phecode |
| 134.1 | Intestinal helminthiases | Infectious Diseases | 0.987 | 0.739 – 1.32 | 0.932 | 53 | 513 | all | phecode |
| 136 | Other infectious and parasitic diseases | Infectious Diseases | 1.03 | 0.996 – 1.07 | 0.0798 | 3279 | 32486 | all | phecode |
| 145 | Cancer of mouth | Neoplasms | 1.04 | 0.98 – 1.09 | 0.211 | 1481 | 14725 | all | phecode |
| 145.1 | Cancer of lip | Neoplasms | 1.21 | 0.957 – 1.54 | 0.11 | 76 | 750 | all | phecode |
| 145.2 | Cancer of tongue | Neoplasms | 1.04 | 0.955 – 1.13 | 0.387 | 645 | 6430 | all | phecode |
| 145.3 | Cancer of major salivary glands | Neoplasms | 0.995 | 0.89 – 1.11 | 0.932 | 361 | 3597 | all | phecode |
| 145.4 | Cancer of the gums | Neoplasms | 0.885 | 0.748 – 1.05 | 0.156 | 166 | 1632 | all | phecode |
| 145.5 | Cancer of the mouth floor | Neoplasms | 1.17 | 1.01 – 1.36 | 0.0327 | 206 | 2048 | all | phecode |
| 149 | Cancer of larynx, pharynx, nasal cavities | Neoplasms | 1.02 | 0.96 – 1.08 | 0.565 | 1290 | 12873 | all | phecode |
| 149.1 | Cancer of oropharynx | Neoplasms | 0.995 | 0.89 – 1.11 | 0.936 | 350 | 3499 | all | phecode |
| 149.2 | Cancer of nasopharynx | Neoplasms | 1.1 | 0.892 – 1.34 | 0.385 | 100 | 1000 | all | phecode |
| 149.3 | Cancer of hypopharynx | Neoplasms | 1.02 | 0.813 – 1.28 | 0.865 | 82 | 819 | all | phecode |
| 149.4 | Cancer of larynx | Neoplasms | 1.06 | 0.95 – 1.18 | 0.304 | 386 | 3857 | all | phecode |
| 149.5 |
Hx of malignant neoplasm of oral cavity andHx of malignant neoplasm of oral cavity and pharynx
|
Neoplasms | 1.06 | 0.967 – 1.16 | 0.219 | 552 | 5505 | all | phecode |
| 149.9 | Cancer of of nasal cavities | Neoplasms | 1 | 0.875 – 1.14 | 0.995 | 240 | 2398 | all | phecode |
| 150 | Cancer of esophagus | Neoplasms | 1.11 | 1.01 – 1.23 | 0.0396 | 433 | 4315 | all | phecode |
| 151 | Cancer of stomach | Neoplasms | 1 | 0.912 – 1.1 | 0.978 | 498 | 4962 | all | phecode |
| 153 | Colorectal cancer | Neoplasms | 0.975 | 0.923 – 1.03 | 0.372 | 1458 | 14383 | all | phecode |
| 153.2 | Colon cancer | Neoplasms | 0.963 | 0.905 – 1.02 | 0.236 | 1160 | 11472 | all | phecode |
| 153.3 |
Malignant neoplasm of rectum, rectosigmoidMalignant neoplasm of rectum, rectosigmoid junction, and anus
|
Neoplasms | 0.979 | 0.909 – 1.05 | 0.575 | 815 | 8093 | all | phecode |
| 155 | Cancer of liver and intrahepatic bile duct | Neoplasms | 1.02 | 0.928 – 1.12 | 0.686 | 511 | 5097 | all | phecode |
| 155.1 | Malignant neoplasm of liver, primary | Neoplasms | 1.08 | 0.966 – 1.21 | 0.17 | 344 | 3433 | all | phecode |
| 157 | Pancreatic cancer | Neoplasms | 1.03 | 0.942 – 1.14 | 0.473 | 503 | 5005 | all | phecode |
| 158 |
Neoplasm of unspecified nature of digestiveNeoplasm of unspecified nature of digestive system
|
Neoplasms | 0.993 | 0.943 – 1.05 | 0.807 | 1623 | 15759 | all | phecode |
| 159 |
Malignant neoplasm of other and ill-definedMalignant neoplasm of other and ill-defined sites within the digestive organs and peritoneum
|
Neoplasms | 1.01 | 0.965 – 1.07 | 0.581 | 1818 | 17869 | all | phecode |
| 159.2 |
Malignant neoplasm of small intestineMalignant neoplasm of small intestine, including duodenum
|
Neoplasms | 0.938 | 0.817 – 1.08 | 0.362 | 221 | 2206 | all | phecode |
| 159.3 |
Malignant neoplasm of gallbladder andMalignant neoplasm of gallbladder and extrahepatic bile ducts
|
Neoplasms | 1.12 | 0.948 – 1.32 | 0.182 | 158 | 1578 | all | phecode |
| 159.4 |
Malignant neoplasm of retroperitoneum andMalignant neoplasm of retroperitoneum and peritoneum
|
Neoplasms | 0.962 | 0.853 – 1.09 | 0.531 | 293 | 2920 | all | phecode |
| 164 | Cancer of intrathoracic organs | Neoplasms | 0.97 | 0.808 – 1.16 | 0.74 | 133 | 1324 | all | phecode |
| 165 | Cancer within the respiratory system | Neoplasms | 1.11 | 1.05 – 1.18 | 0.000241 | 1336 | 13340 | all | phecode |
| 165.1 | Cancer of bronchus; lung | Neoplasms | 1.14 | 1.06 – 1.21 | 0.000111 | 1057 | 10552 | all | phecode |
| 170 | Cancer of bone and connective tissue | Neoplasms | 1 | 0.951 – 1.05 | 0.995 | 1792 | 17850 | all | phecode |
| 170.1 | Bone cancer | Neoplasms | 1 | 0.931 – 1.08 | 0.907 | 773 | 7690 | all | phecode |
| 170.2 | Cancer of connective tissue | Neoplasms | 0.998 | 0.941 – 1.06 | 0.954 | 1266 | 12632 | all | phecode |
| 172 | Skin cancer | Neoplasms | 0.961 | 0.937 – 0.985 | 0.00199 | 8608 | 33186 | all | phecode |
| 172.1 | Melanomas of skin, dx or hx | Neoplasms | 0.948 | 0.919 – 0.977 | 0.000621 | 5330 | 30106 | all | phecode |
| 172.11 | Melanomas of skin | Neoplasms | 0.968 | 0.932 – 1.01 | 0.0986 | 3100 | 25064 | all | phecode |
| 172.2 | Other non-epithelial cancer of skin | Neoplasms | 0.955 | 0.929 – 0.982 | 0.00111 | 7095 | 30462 | all | phecode |
| 172.21 | Basal cell carcinoma | Neoplasms | 0.928 | 0.895 – 0.962 | 5.9e-05 | 3690 | 23868 | all | phecode |
| 172.22 | Squamous cell carcinoma | Neoplasms | 0.976 | 0.934 – 1.02 | 0.29 | 2414 | 17683 | all | phecode |
| 172.3 | Carcinoma in situ of skin | Neoplasms | 0.945 | 0.894 – 0.999 | 0.0472 | 1482 | 12326 | all | phecode |
| 173 | Neoplasm of uncertain behavior of skin | Neoplasms | 0.949 | 0.905 – 0.995 | 0.0308 | 1997 | 18755 | all | phecode |
| 174 | Breast cancer | Neoplasms | 0.967 | 0.929 – 1.01 | 0.0946 | 3186 | 15514 | all | phecode |
| 174.1 | Breast cancer [female] | Neoplasms | 0.956 | 0.918 – 0.996 | 0.0312 | 3036 | 14701 | all | phecode |
| 174.11 | Malignant neoplasm of female breast | Neoplasms | 0.958 | 0.919 – 0.998 | 0.0397 | 2991 | 14639 | all | phecode |
| 174.3 | Neoplasm of uncertain behavior of breast | Neoplasms | 1.02 | 0.889 – 1.18 | 0.748 | 233 | 2307 | all | phecode |
| 175 | Acquired absence of breast | Neoplasms | 0.969 | 0.903 – 1.04 | 0.376 | 919 | 8920 | all | phecode |
| 180 | Cervical cancer and dysplasia | Neoplasms | 1.07 | 1.01 – 1.13 | 0.0257 | 1431 | 12185 | all | phecode |
| 180.1 | Cervical cancer | Neoplasms | 1.15 | 1.04 – 1.26 | 0.00416 | 500 | 4982 | all | phecode |
| 180.3 |
Cervical intraepithelial neoplasia [CIN]Cervical intraepithelial neoplasia [CIN] [Cervical dysplasia]
|
Neoplasms | 1.03 | 0.969 – 1.1 | 0.306 | 1048 | 9323 | all | phecode |
| 182 | Malignant neoplasm of uterus | Neoplasms | 0.953 | 0.882 – 1.03 | 0.217 | 765 | 7613 | all | phecode |
| 184 | Cancer of other female genital organs | Neoplasms | 0.992 | 0.932 – 1.05 | 0.793 | 1191 | 11592 | all | phecode |
| 184.1 |
Malignant neoplasm of ovary and other uterineMalignant neoplasm of ovary and other uterine adnexa
|
Neoplasms | 1 | 0.919 – 1.1 | 0.93 | 573 | 5719 | all | phecode |
| 184.11 | Malignant neoplasm of ovary | Neoplasms | 0.922 | 0.832 – 1.02 | 0.119 | 432 | 4309 | all | phecode |
| 184.2 |
Cancer of other female genital organsCancer of other female genital organs (excluding uterus and ovary)
|
Neoplasms | 1.03 | 0.947 – 1.13 | 0.471 | 608 | 6057 | all | phecode |
| 185 | Cancer of prostate | Neoplasms | 0.944 | 0.903 – 0.986 | 0.00992 | 2901 | 10342 | all | phecode |
| 187 | Cancer of other male genital organs | Neoplasms | 1.05 | 0.938 – 1.18 | 0.401 | 339 | 3384 | all | phecode |
| 187.1 |
Malignant neoplasm of unspecified male genitalMalignant neoplasm of unspecified male genital organ
|
Neoplasms | 1.11 | 0.912 – 1.35 | 0.302 | 115 | 1141 | all | phecode |
| 187.2 | Malignant neoplasm of testis | Neoplasms | 1.07 | 0.911 – 1.24 | 0.428 | 183 | 1830 | all | phecode |
| 187.8 |
Neoplasm of uncertain behavior of male genitalNeoplasm of uncertain behavior of male genital organs
|
Neoplasms | 1 | 0.754 – 1.33 | 0.998 | 57 | 562 | all | phecode |
| 189 |
Cancer of urinary organs (incl. kidney andCancer of urinary organs (incl. kidney and bladder)
|
Neoplasms | 1.08 | 1.03 – 1.12 | 0.000252 | 2923 | 23541 | all | phecode |
| 189.1 | Cancer of kidney and renal pelvis | Neoplasms | 1.1 | 1.04 – 1.16 | 0.000801 | 1450 | 14437 | all | phecode |
| 189.11 | Malignant neoplasm of kidney, except pelvis | Neoplasms | 1.11 | 1.04 – 1.18 | 0.000646 | 1267 | 12655 | all | phecode |
| 189.12 | Malignant neoplasm of renal pelvis | Neoplasms | 1.14 | 0.997 – 1.31 | 0.0554 | 237 | 2347 | all | phecode |
| 189.2 | Cancer of bladder | Neoplasms | 1.1 | 1.04 – 1.16 | 0.000266 | 1783 | 15224 | all | phecode |
| 189.21 | Malignant neoplasm of bladder | Neoplasms | 1.11 | 1.06 – 1.17 | 5.83e-05 | 1657 | 14178 | all | phecode |
| 189.4 | Malignant neoplasm of other urinary organs | Neoplasms | 1.14 | 1.05 – 1.24 | 0.00138 | 678 | 6586 | all | phecode |
| 190 | Cancer of eye | Neoplasms | 1.07 | 0.899 – 1.27 | 0.458 | 138 | 1374 | all | phecode |
| 191 |
Manlignant and unknown neoplasms of brain andManlignant and unknown neoplasms of brain and nervous system
|
Neoplasms | 0.993 | 0.931 – 1.06 | 0.827 | 1078 | 10771 | all | phecode |
| 191.1 | Cancer of brain and nervous system | Neoplasms | 0.937 | 0.866 – 1.01 | 0.109 | 706 | 7052 | all | phecode |
| 191.11 | Cancer of brain | Neoplasms | 0.955 | 0.876 – 1.04 | 0.297 | 600 | 5996 | all | phecode |
| 193 | Thyroid cancer | Neoplasms | 0.994 | 0.928 – 1.06 | 0.861 | 945 | 9393 | all | phecode |
| 194 | Cancer of other endocrine glands | Neoplasms | 1.02 | 0.938 – 1.12 | 0.591 | 579 | 5759 | all | phecode |
| 195 | Cancer, suspected or other | Neoplasms | 0.995 | 0.974 – 1.02 | 0.638 | 16962 | 26401 | all | phecode |
| 195.1 | Malignant neoplasm, other | Neoplasms | 0.995 | 0.974 – 1.02 | 0.635 | 16670 | 26384 | all | phecode |
| 195.3 | Malignant neoplasm of head, face, and neck | Neoplasms | 1.09 | 1.02 – 1.16 | 0.00955 | 1103 | 9766 | all | phecode |
| 196 | Radiotherapy | Neoplasms | 0.991 | 0.948 – 1.04 | 0.682 | 2427 | 17006 | all | phecode |
| 197 | Chemotherapy | Neoplasms | 0.99 | 0.958 – 1.02 | 0.528 | 4952 | 23797 | all | phecode |
| 198 | Secondary malignant neoplasm | Neoplasms | 1.01 | 0.975 – 1.04 | 0.724 | 5801 | 23481 | all | phecode |
| 198.1 | Secondary malignancy of lymph nodes | Neoplasms | 0.996 | 0.961 – 1.03 | 0.842 | 3677 | 21489 | all | phecode |
| 198.2 | Secondary malignancy of respiratory organs | Neoplasms | 0.954 | 0.894 – 1.02 | 0.154 | 1072 | 10334 | all | phecode |
| 198.3 |
Secondary malignant neoplasm of digestiveSecondary malignant neoplasm of digestive systems
|
Neoplasms | 0.937 | 0.872 – 1.01 | 0.0764 | 866 | 8538 | all | phecode |
| 198.4 | Secondary malignant neoplasm of liver | Neoplasms | 0.941 | 0.871 – 1.02 | 0.118 | 767 | 7558 | all | phecode |
| 198.5 | Secondary malignancy of brain/spine | Neoplasms | 0.962 | 0.884 – 1.05 | 0.366 | 640 | 6338 | all | phecode |
| 198.6 | Secondary malignancy of bone | Neoplasms | 0.973 | 0.905 – 1.04 | 0.448 | 866 | 8307 | all | phecode |
| 198.7 | Secondary malignant neoplasm of skin | Neoplasms | 0.967 | 0.861 – 1.09 | 0.573 | 336 | 3253 | all | phecode |
| 199 | Neoplasm of uncertain behavior | Neoplasms | 0.996 | 0.966 – 1.03 | 0.775 | 5693 | 25767 | all | phecode |
| 199.4 | Neurofibromatosis | Neoplasms | 0.959 | 0.776 – 1.19 | 0.703 | 88 | 880 | all | phecode |
| 200 | Myeloproliferative disease | Neoplasms | 0.936 | 0.878 – 0.997 | 0.0399 | 1113 | 11098 | all | phecode |
| 200.1 | Polycythemia vera | Neoplasms | 0.92 | 0.802 – 1.06 | 0.237 | 231 | 2310 | all | phecode |
| 201 | Hodgkin's disease | Neoplasms | 0.956 | 0.812 – 1.12 | 0.587 | 172 | 1705 | all | phecode |
| 202 | Cancer of other lymphoid, histiocytic tissue | Neoplasms | 0.996 | 0.944 – 1.05 | 0.869 | 1559 | 15571 | all | phecode |
| 202.2 | Non-Hodgkins lymphoma | Neoplasms | 0.993 | 0.937 – 1.05 | 0.8 | 1329 | 13268 | all | phecode |
| 202.21 | Nodular lymphoma | Neoplasms | 0.986 | 0.91 – 1.07 | 0.722 | 693 | 6923 | all | phecode |
| 202.22 | Reticulosarcoma | Neoplasms | 0.906 | 0.771 – 1.06 | 0.228 | 170 | 1693 | all | phecode |
| 202.24 | Large cell lymphoma | Neoplasms | 0.923 | 0.783 – 1.09 | 0.345 | 160 | 1586 | all | phecode |
| 204 | Leukemia | Neoplasms | 0.948 | 0.875 – 1.03 | 0.192 | 689 | 6876 | all | phecode |
| 204.1 | Lymphoid leukemia | Neoplasms | 0.969 | 0.846 – 1.11 | 0.653 | 236 | 2354 | all | phecode |
| 204.11 | Lymphoid leukemia, acute | Neoplasms | 0.915 | 0.714 – 1.17 | 0.478 | 74 | 734 | all | phecode |
| 204.12 | Lymphoid leukemia, chronic | Neoplasms | 0.984 | 0.839 – 1.15 | 0.841 | 173 | 1724 | all | phecode |
| 204.2 | Myeloid leukemia | Neoplasms | 0.952 | 0.836 – 1.08 | 0.46 | 265 | 2633 | all | phecode |
| 204.21 | Myeloid leukemia, acute | Neoplasms | 0.921 | 0.777 – 1.09 | 0.341 | 153 | 1516 | all | phecode |
| 204.22 | Myeloid leukemia, chronic | Neoplasms | 0.99 | 0.76 – 1.29 | 0.942 | 61 | 610 | all | phecode |
| 204.4 | Multiple myeloma | Neoplasms | 0.96 | 0.833 – 1.11 | 0.573 | 217 | 2162 | all | phecode |
| 208 | Benign neoplasm of colon | Neoplasms | 0.982 | 0.96 – 1 | 0.121 | 10303 | 34953 | all | phecode |
| 209 | Neuroendocrine tumors | Neoplasms | 0.987 | 0.868 – 1.12 | 0.841 | 258 | 2580 | all | phecode |
| 210 | Benign neoplasm of lip, oral cavity, and pharynx | Neoplasms | 1.02 | 0.973 – 1.07 | 0.404 | 1891 | 18839 | all | phecode |
| 211 |
Benign neoplasm of other parts of digestiveBenign neoplasm of other parts of digestive system
|
Neoplasms | 1.01 | 0.988 – 1.04 | 0.311 | 7329 | 36606 | all | phecode |
| 212 |
Benign neoplasm of respiratory andBenign neoplasm of respiratory and intrathoracic organs
|
Neoplasms | 1.03 | 0.981 – 1.08 | 0.232 | 1843 | 18412 | all | phecode |
| 213 | Benign neoplasm of bone and articular cartilage | Neoplasms | 1.01 | 0.963 – 1.07 | 0.603 | 1677 | 15527 | all | phecode |
| 214 | Lipoma | Neoplasms | 0.958 | 0.906 – 1.01 | 0.133 | 1437 | 14132 | all | phecode |
| 214.1 | Lipoma of skin and subcutaneous tissue | Neoplasms | 0.948 | 0.883 – 1.02 | 0.138 | 883 | 8710 | all | phecode |
| 215 |
Other benign neoplasm of connective and otherOther benign neoplasm of connective and other soft tissue
|
Neoplasms | 0.99 | 0.96 – 1.02 | 0.546 | 4528 | 39509 | all | phecode |
| 216 | Benign neoplasm of skin | Neoplasms | 0.945 | 0.925 – 0.966 | 3.88e-07 | 11528 | 34919 | all | phecode |
| 216.1 | Screening for malignant neoplasms of the skin | Neoplasms | 0.875 | 0.751 – 1.02 | 0.0896 | 174 | 1701 | all | phecode |
| 217 | Vascular hamartomas and non-neoplastic nevi | Neoplasms | 0.893 | 0.85 – 0.939 | 1.02e-05 | 1786 | 17184 | all | phecode |
| 217.1 | Nevus, non-neoplastic | Neoplasms | 0.872 | 0.827 – 0.918 | 2.03e-07 | 1679 | 16116 | all | phecode |
| 218 | Benign neoplasm of uterus | Neoplasms | 0.986 | 0.952 – 1.02 | 0.414 | 4301 | 16661 | all | phecode |
| 218.1 | Uterine leiomyoma | Neoplasms | 0.963 | 0.916 – 1.01 | 0.141 | 1835 | 15733 | all | phecode |
| 218.2 | Other benign neoplasm of uterus | Neoplasms | 0.995 | 0.958 – 1.03 | 0.811 | 3403 | 16447 | all | phecode |
| 220 | Benign neoplasm of ovary | Neoplasms | 0.938 | 0.873 – 1.01 | 0.0751 | 893 | 8783 | all | phecode |
| 221 | Benign neoplasm of other female genital organs | Neoplasms | 1.02 | 0.977 – 1.07 | 0.318 | 2042 | 14248 | all | phecode |
| 222 | Benign neoplasm of male genital organs | Neoplasms | 0.96 | 0.902 – 1.02 | 0.199 | 1133 | 10663 | all | phecode |
| 223 |
Benign neoplasm of kidney and other urinaryBenign neoplasm of kidney and other urinary organs
|
Neoplasms | 1.04 | 0.987 – 1.09 | 0.149 | 1801 | 12657 | all | phecode |
| 224 | Benign neoplasm of eye | Neoplasms | 1.05 | 0.966 – 1.14 | 0.261 | 691 | 6752 | all | phecode |
| 224.1 | Benign neoplasm of eye, uveal | Neoplasms | 1.04 | 0.951 – 1.13 | 0.417 | 595 | 5773 | all | phecode |
| 225 |
Benign neoplasm of brain and other parts ofBenign neoplasm of brain and other parts of nervous system
|
Neoplasms | 0.961 | 0.905 – 1.02 | 0.202 | 1209 | 12074 | all | phecode |
| 225.1 |
Benign neoplasm of brain, cranial nervesBenign neoplasm of brain, cranial nerves, meninges
|
Neoplasms | 0.966 | 0.902 – 1.03 | 0.317 | 947 | 9454 | all | phecode |
| 225.2 | Benign neoplasm of spinal cord, meninges | Neoplasms | 0.927 | 0.819 – 1.05 | 0.225 | 289 | 2890 | all | phecode |
| 226 | Benign neoplasm of thyroid glands | Neoplasms | 0.986 | 0.931 – 1.05 | 0.642 | 1329 | 13264 | all | phecode |
| 227 |
Benign neoplasm of other endocrine glands andBenign neoplasm of other endocrine glands and related structures
|
Neoplasms | 0.981 | 0.931 – 1.03 | 0.454 | 1690 | 16896 | all | phecode |
| 227.1 | Benign neoplasm of adrenal gland | Neoplasms | 1.12 | 1.01 – 1.24 | 0.024 | 467 | 4644 | all | phecode |
| 227.2 | Benign neoplasm of parathyroid gland | Neoplasms | 0.907 | 0.841 – 0.979 | 0.0123 | 795 | 7941 | all | phecode |
| 227.3 |
Benign neoplasm of pituitary gland andBenign neoplasm of pituitary gland and craniopharyngeal duct (pouch)
|
Neoplasms | 0.955 | 0.862 – 1.06 | 0.383 | 435 | 4350 | all | phecode |
| 228 | Hemangioma and lymphangioma, any site | Neoplasms | 0.953 | 0.911 – 0.997 | 0.0386 | 2149 | 20946 | all | phecode |
| 228.1 | Hemangioma of skin and subcutaneous tissue | Neoplasms | 0.969 | 0.915 – 1.03 | 0.289 | 1356 | 13336 | all | phecode |
| 229 | Benign neoplasm of unspecified sites | Neoplasms | 1.01 | 0.985 – 1.04 | 0.451 | 7767 | 36615 | all | phecode |
| 229.1 | Benign neoplasm of lymph nodes | Neoplasms | 1.01 | 0.985 – 1.04 | 0.363 | 5743 | 34218 | all | phecode |
| 240 | Simple and unspecified goiter | Endocrine/metabolic | 0.986 | 0.923 – 1.05 | 0.666 | 1031 | 9761 | all | phecode |
| 241 | Nontoxic nodular goiter | Endocrine/metabolic | 0.986 | 0.947 – 1.03 | 0.478 | 2910 | 22227 | all | phecode |
| 241.1 | Nontoxic uninodular goiter | Endocrine/metabolic | 0.976 | 0.933 – 1.02 | 0.282 | 2265 | 19902 | all | phecode |
| 241.2 | Nontoxic multinodular goiter | Endocrine/metabolic | 0.941 | 0.887 – 0.998 | 0.0444 | 1304 | 12479 | all | phecode |
| 242 | Thyrotoxicosis with or without goiter | Endocrine/metabolic | 1 | 0.945 – 1.06 | 0.999 | 1400 | 13425 | all | phecode |
| 242.1 | Graves' disease | Endocrine/metabolic | 1.08 | 0.984 – 1.19 | 0.107 | 515 | 5068 | all | phecode |
| 242.2 | Toxic multinodular goiter | Endocrine/metabolic | 0.87 | 0.722 – 1.05 | 0.147 | 124 | 1224 | all | phecode |
| 242.3 | Exophthalmos | Endocrine/metabolic | 1.03 | 0.91 – 1.16 | 0.66 | 292 | 2898 | all | phecode |
| 242.31 | Thyrotoxic exophthalmos | Endocrine/metabolic | 1.16 | 0.973 – 1.38 | 0.0989 | 144 | 1432 | all | phecode |
| 244 | Hypothyroidism | Endocrine/metabolic | 1 | 0.977 – 1.03 | 0.866 | 8099 | 32717 | all | phecode |
| 244.1 | Secondary hypothyroidism | Endocrine/metabolic | 0.991 | 0.942 – 1.04 | 0.728 | 1762 | 17230 | all | phecode |
| 244.2 | Acquired hypothyroidism | Endocrine/metabolic | 1.01 | 0.955 – 1.08 | 0.651 | 1261 | 11982 | all | phecode |
| 244.4 | Hypothyroidism NOS | Endocrine/metabolic | 1 | 0.975 – 1.03 | 0.943 | 7542 | 32208 | all | phecode |
| 245 | Thyroiditis | Endocrine/metabolic | 0.988 | 0.918 – 1.06 | 0.756 | 832 | 7882 | all | phecode |
| 245.2 | Chronic thyroiditis | Endocrine/metabolic | 0.955 | 0.881 – 1.03 | 0.261 | 686 | 6517 | all | phecode |
| 245.21 | Chronic lymphocytic thyroiditis | Endocrine/metabolic | 0.956 | 0.882 – 1.04 | 0.275 | 679 | 6449 | all | phecode |
| 246 | Other disorders of thyroid | Endocrine/metabolic | 0.985 | 0.957 – 1.01 | 0.295 | 6129 | 30240 | all | phecode |
| 246.2 | Thyroid cyst | Endocrine/metabolic | 1.07 | 0.867 – 1.31 | 0.546 | 101 | 960 | all | phecode |
| 246.7 | Abnormal results of function study of thyroid | Endocrine/metabolic | 0.971 | 0.905 – 1.04 | 0.407 | 886 | 8696 | all | phecode |
| 249 | Secondary diabetes mellitus | Endocrine/metabolic | 0.993 | 0.925 – 1.07 | 0.838 | 1150 | 8340 | all | phecode |
| 250 | Diabetes mellitus | Endocrine/metabolic | 1.03 | 1.01 – 1.05 | 0.00926 | 13947 | 31815 | all | phecode |
| 250.1 | Type 1 diabetes | Endocrine/metabolic | 1.03 | 0.974 – 1.1 | 0.273 | 2364 | 11758 | all | phecode |
| 250.11 | Type 1 diabetes with ketoacidosis | Endocrine/metabolic | 1.03 | 0.859 – 1.23 | 0.773 | 262 | 960 | all | phecode |
| 250.12 | Type 1 diabetes with renal manifestations | Endocrine/metabolic | 1.05 | 0.932 – 1.18 | 0.436 | 551 | 2686 | all | phecode |
| 250.13 | Type 1 diabetes with ophthalmic manifestations | Endocrine/metabolic | 0.966 | 0.866 – 1.08 | 0.542 | 784 | 3018 | all | phecode |
| 250.14 | Type 1 diabetes with neurological manifestations | Endocrine/metabolic | 1.07 | 0.956 – 1.2 | 0.236 | 638 | 2675 | all | phecode |
| 250.15 |
Diabetes type 1 with peripheral circulatoryDiabetes type 1 with peripheral circulatory disorders
|
Endocrine/metabolic | 1.17 | 0.956 – 1.43 | 0.128 | 155 | 850 | all | phecode |
| 250.2 | Type 2 diabetes | Endocrine/metabolic | 1.04 | 1.02 – 1.07 | 0.000827 | 9843 | 29688 | all | phecode |
| 250.21 | Type 2 diabetes with ketoacidosis | Endocrine/metabolic | 1.09 | 0.929 – 1.27 | 0.299 | 282 | 1327 | all | phecode |
| 250.22 | Type 2 diabetes with renal manifestations | Endocrine/metabolic | 1.04 | 0.984 – 1.1 | 0.161 | 1941 | 13510 | all | phecode |
| 250.23 | Type 2 diabetes with ophthalmic manifestations | Endocrine/metabolic | 1.05 | 0.98 – 1.12 | 0.177 | 1643 | 9668 | all | phecode |
| 250.24 | Type 2 diabetes with neurological manifestations | Endocrine/metabolic | 1.08 | 1.03 – 1.14 | 0.00229 | 2557 | 16502 | all | phecode |
| 250.25 |
Diabetes type 2 with peripheral circulatoryDiabetes type 2 with peripheral circulatory disorders
|
Endocrine/metabolic | 0.999 | 0.92 – 1.08 | 0.974 | 860 | 6143 | all | phecode |
| 250.3 | Insulin pump user | Endocrine/metabolic | 1.07 | 1.02 – 1.11 | 0.00437 | 3496 | 20809 | all | phecode |
| 250.4 | Abnormal glucose | Endocrine/metabolic | 1 | 0.977 – 1.03 | 0.783 | 8385 | 30645 | all | phecode |
| 250.41 | Impaired fasting glucose | Endocrine/metabolic | 0.975 | 0.926 – 1.03 | 0.335 | 1870 | 15861 | all | phecode |
| 250.42 | Other abnormal glucose | Endocrine/metabolic | 1 | 0.976 – 1.03 | 0.796 | 7553 | 30071 | all | phecode |
| 250.5 | Glycosuria or Acetonuria | Endocrine/metabolic | 1.22 | 1 – 1.48 | 0.0495 | 136 | 1067 | all | phecode |
| 250.6 | Polyneuropathy in diabetes | Endocrine/metabolic | 1.07 | 1.01 – 1.13 | 0.0166 | 2132 | 13390 | all | phecode |
| 250.7 | Diabetic retinopathy | Endocrine/metabolic | 1.03 | 0.97 – 1.09 | 0.37 | 1691 | 10517 | all | phecode |
| 251 | Other disorders of pancreatic internal secretion | Endocrine/metabolic | 1.06 | 0.991 – 1.13 | 0.089 | 991 | 8469 | all | phecode |
| 251.1 | Hypoglycemia | Endocrine/metabolic | 1.09 | 1.02 – 1.17 | 0.0124 | 1207 | 8570 | all | phecode |
| 252 | Disorders of parathyroid gland | Endocrine/metabolic | 0.976 | 0.933 – 1.02 | 0.275 | 2282 | 22119 | all | phecode |
| 252.1 | Hyperparathyroidism | Endocrine/metabolic | 0.98 | 0.935 – 1.03 | 0.39 | 2088 | 20335 | all | phecode |
| 252.2 | Hypoparathyroidism | Endocrine/metabolic | 0.986 | 0.899 – 1.08 | 0.773 | 508 | 5073 | all | phecode |
| 253 |
Disorders of the pituitary gland and itsDisorders of the pituitary gland and its hypothalamic control
|
Endocrine/metabolic | 1.03 | 0.957 – 1.1 | 0.453 | 859 | 8544 | all | phecode |
| 253.1 | Pituitary hyperfunction | Endocrine/metabolic | 1.01 | 0.89 – 1.15 | 0.838 | 263 | 2621 | all | phecode |
| 253.11 | Acromegaly and gigantism | Endocrine/metabolic | 0.913 | 0.722 – 1.15 | 0.446 | 83 | 826 | all | phecode |
| 253.2 | Pituitary hypofunction | Endocrine/metabolic | 0.989 | 0.862 – 1.13 | 0.869 | 226 | 2250 | all | phecode |
| 253.3 | Diabetes insipidus | Endocrine/metabolic | 1.13 | 0.909 – 1.41 | 0.266 | 86 | 860 | all | phecode |
| 253.4 | Anterior pituitary disorders | Endocrine/metabolic | 0.942 | 0.781 – 1.14 | 0.528 | 121 | 1209 | all | phecode |
| 253.7 | Other disorders of neurohypophysis | Endocrine/metabolic | 0.974 | 0.797 – 1.19 | 0.796 | 108 | 1080 | all | phecode |
| 255 | Disorders of adrenal glands | Endocrine/metabolic | 1.01 | 0.956 – 1.07 | 0.74 | 1506 | 14869 | all | phecode |
| 255.1 | Adrenal hyperfunction | Endocrine/metabolic | 0.921 | 0.825 – 1.03 | 0.139 | 373 | 3730 | all | phecode |
| 255.11 | Cushing's syndrome | Endocrine/metabolic | 0.91 | 0.779 – 1.06 | 0.235 | 183 | 1830 | all | phecode |
| 255.12 | Hyperaldosteronism | Endocrine/metabolic | 0.873 | 0.727 – 1.05 | 0.144 | 135 | 1350 | all | phecode |
| 255.2 | Adrenal hypofunction | Endocrine/metabolic | 1.02 | 0.934 – 1.11 | 0.707 | 626 | 6239 | all | phecode |
| 255.21 | Glucocorticoid deficiency | Endocrine/metabolic | 1.03 | 0.947 – 1.13 | 0.463 | 596 | 5941 | all | phecode |
| 256 | Ovarian dysfunction | Endocrine/metabolic | 0.979 | 0.92 – 1.04 | 0.511 | 1146 | 10513 | all | phecode |
| 256.4 | Polycystic ovaries | Endocrine/metabolic | 1.03 | 0.958 – 1.12 | 0.398 | 742 | 7128 | all | phecode |
| 257 | Testicular dysfunction | Endocrine/metabolic | 0.994 | 0.93 – 1.06 | 0.857 | 1015 | 9238 | all | phecode |
| 257.1 | Testicular hypofunction | Endocrine/metabolic | 0.985 | 0.921 – 1.05 | 0.665 | 983 | 8933 | all | phecode |
| 258 | Iatrogenic endocrine disorders | Endocrine/metabolic | 1.1 | 0.89 – 1.35 | 0.39 | 91 | 910 | all | phecode |
| 258.1 | Postablative ovarian failure | Endocrine/metabolic | 0.753 | 0.613 – 0.924 | 0.00668 | 109 | 1090 | all | phecode |
| 259 | Other endocrine disorders | Endocrine/metabolic | 0.951 | 0.891 – 1.02 | 0.131 | 1038 | 10259 | all | phecode |
| 260 | Protein-calorie malnutrition | Endocrine/metabolic | 1.07 | 1.03 – 1.11 | 0.000762 | 2880 | 26812 | all | phecode |
| 260.1 | Cachexia | Endocrine/metabolic | 1.05 | 0.926 – 1.19 | 0.46 | 292 | 2911 | all | phecode |
| 260.2 | severe protein-calorie malnutrition | Endocrine/metabolic | 1.1 | 1.05 – 1.16 | 0.000159 | 1691 | 16847 | all | phecode |
| 260.22 | Nutritional marasmus | Endocrine/metabolic | 1.15 | 1.06 – 1.25 | 0.00126 | 614 | 6140 | all | phecode |
| 260.3 | Adult failure to thrive | Endocrine/metabolic | 1.07 | 0.979 – 1.16 | 0.14 | 629 | 6236 | all | phecode |
| 260.6 | Anorexia | Endocrine/metabolic | 1.03 | 0.958 – 1.11 | 0.423 | 868 | 8591 | all | phecode |
| 260.7 | Polyphagia | Endocrine/metabolic | 0.991 | 0.762 – 1.29 | 0.946 | 65 | 643 | all | phecode |
| 261 | Vitamin deficiency | Endocrine/metabolic | 0.99 | 0.965 – 1.02 | 0.445 | 7718 | 35203 | all | phecode |
| 261.1 | Vitamin A deficiency | Endocrine/metabolic | 1.04 | 0.818 – 1.32 | 0.743 | 69 | 690 | all | phecode |
| 261.2 | Vitamin B-complex deficiencies | Endocrine/metabolic | 1.01 | 0.938 – 1.08 | 0.824 | 857 | 8405 | all | phecode |
| 261.4 | Vitamin D deficiency | Endocrine/metabolic | 0.986 | 0.96 – 1.01 | 0.307 | 7255 | 35225 | all | phecode |
| 261.41 | Rickets or osteomalacia | Endocrine/metabolic | 0.87 | 0.661 – 1.15 | 0.324 | 52 | 511 | all | phecode |
| 262 | Mineral deficiency NEC | Endocrine/metabolic | 0.979 | 0.921 – 1.04 | 0.495 | 1182 | 11676 | all | phecode |
| 263 | Other nutritional deficiency | Endocrine/metabolic | 0.996 | 0.946 – 1.05 | 0.888 | 1651 | 15788 | all | phecode |
| 264 | Lack of normal physiological development | Endocrine/metabolic | 1.02 | 0.889 – 1.17 | 0.789 | 239 | 2301 | all | phecode |
| 264.2 | Failure to thrive (childhood) | Endocrine/metabolic | 1.08 | 0.89 – 1.3 | 0.447 | 122 | 1220 | all | phecode |
| 264.9 |
Lack of normal physiological developmentLack of normal physiological development, unspecified
|
Endocrine/metabolic | 0.926 | 0.734 – 1.17 | 0.516 | 81 | 772 | all | phecode |
| 269 | Proteinuria | Endocrine/metabolic | 0.992 | 0.941 – 1.05 | 0.77 | 1694 | 13981 | all | phecode |
| 270 |
Disorders of protein plasma/amino-acidDisorders of protein plasma/amino-acid transport and metabolism
|
Endocrine/metabolic | 1.01 | 0.945 – 1.08 | 0.761 | 967 | 9575 | all | phecode |
| 270.1 | Disturbances of amino-acid transport | Endocrine/metabolic | 0.996 | 0.846 – 1.17 | 0.962 | 170 | 1697 | all | phecode |
| 270.11 |
Disturbances of sulphur-bearing amino-acidDisturbances of sulphur-bearing amino-acid metabolism
|
Endocrine/metabolic | 1.02 | 0.851 – 1.22 | 0.834 | 134 | 1334 | all | phecode |
| 270.2 | Disorders of amino-acid metabolism | Endocrine/metabolic | 0.991 | 0.797 – 1.23 | 0.932 | 96 | 954 | all | phecode |
| 270.3 | Disorders of plasma protein metabolism | Endocrine/metabolic | 1.02 | 0.943 – 1.1 | 0.651 | 737 | 7303 | all | phecode |
| 270.32 | Paraproteinemia | Endocrine/metabolic | 1.03 | 0.925 – 1.14 | 0.599 | 384 | 3781 | all | phecode |
| 270.33 | Amyloidosis | Endocrine/metabolic | 1.18 | 0.926 – 1.49 | 0.185 | 71 | 695 | all | phecode |
| 270.34 | Alpha-1-antitrypsin deficiency | Endocrine/metabolic | 0.917 | 0.713 – 1.18 | 0.5 | 69 | 690 | all | phecode |
| 270.38 |
Other specified disorders of plasma proteinOther specified disorders of plasma protein metabolism
|
Endocrine/metabolic | 1.01 | 0.896 – 1.13 | 0.907 | 299 | 2984 | all | phecode |
| 271 |
Disorders of carbohydrate transport andDisorders of carbohydrate transport and metabolism
|
Endocrine/metabolic | 0.969 | 0.932 – 1.01 | 0.122 | 2907 | 28132 | all | phecode |
| 271.3 |
Intestinal disaccharidase deficiencies andIntestinal disaccharidase deficiencies and disaccharide malabsorption
|
Endocrine/metabolic | 0.971 | 0.933 – 1.01 | 0.152 | 2827 | 27425 | all | phecode |
| 271.9 |
Other disorders of carbohydrate transport andOther disorders of carbohydrate transport and metabolism
|
Endocrine/metabolic | 0.914 | 0.743 – 1.12 | 0.393 | 102 | 1007 | all | phecode |
| 272 | Disorders of lipoid metabolism | Endocrine/metabolic | 1.04 | 1.01 – 1.06 | 0.0012 | 18881 | 26670 | all | phecode |
| 272.1 | Hyperlipidemia | Endocrine/metabolic | 1.04 | 1.01 – 1.06 | 0.00118 | 18843 | 26654 | all | phecode |
| 272.11 | Hypercholesterolemia | Endocrine/metabolic | 1.02 | 0.989 – 1.05 | 0.199 | 5928 | 21600 | all | phecode |
| 272.12 | Hyperglyceridemia | Endocrine/metabolic | 1.02 | 0.96 – 1.08 | 0.551 | 1360 | 11837 | all | phecode |
| 272.13 | Mixed hyperlipidemia | Endocrine/metabolic | 1.03 | 0.992 – 1.07 | 0.121 | 3538 | 18449 | all | phecode |
| 272.9 | Unspecified disorder of lipoid metabolism | Endocrine/metabolic | 0.948 | 0.843 – 1.07 | 0.378 | 313 | 3011 | all | phecode |
| 274 | Gout and other crystal arthropathies | Endocrine/metabolic | 0.989 | 0.948 – 1.03 | 0.596 | 2524 | 22729 | all | phecode |
| 274.1 | Gout | Endocrine/metabolic | 0.987 | 0.946 – 1.03 | 0.56 | 2409 | 21991 | all | phecode |
| 274.11 | Gouty arthropathy | Endocrine/metabolic | 0.987 | 0.925 – 1.05 | 0.68 | 1082 | 10576 | all | phecode |
| 274.2 | Crystal arthropathies | Endocrine/metabolic | 0.913 | 0.783 – 1.06 | 0.241 | 195 | 1890 | all | phecode |
| 274.21 | Chondrocalcinosis | Endocrine/metabolic | 0.917 | 0.782 – 1.07 | 0.283 | 183 | 1772 | all | phecode |
| 275 | Disorders of mineral metabolism | Endocrine/metabolic | 1.02 | 0.985 – 1.05 | 0.307 | 4357 | 37091 | all | phecode |
| 275.1 | Disorders of iron metabolism | Hematopoietic | 1.07 | 0.924 – 1.23 | 0.385 | 218 | 2180 | all | phecode |
| 275.11 | Hereditary hemochromatosis | Hematopoietic | 1.16 | 0.936 – 1.43 | 0.178 | 99 | 990 | all | phecode |
| 275.2 | Disorders of copper metabolism | Endocrine/metabolic | 1.01 | 0.771 – 1.32 | 0.954 | 62 | 614 | all | phecode |
| 275.3 | Disorders of magnesium metabolism | Endocrine/metabolic | 1.03 | 0.972 – 1.1 | 0.282 | 1154 | 11504 | all | phecode |
| 275.5 | Disorders of calcium/phosphorus metabolism | Endocrine/metabolic | 1 | 0.965 – 1.04 | 0.984 | 3369 | 31544 | all | phecode |
| 275.51 | Hypocalcemia | Endocrine/metabolic | 0.987 | 0.92 – 1.06 | 0.702 | 898 | 8969 | all | phecode |
| 275.53 | Disorders of phosphorus metabolism | Endocrine/metabolic | 1.02 | 0.966 – 1.08 | 0.443 | 1366 | 13634 | all | phecode |
| 275.6 | Hypercalcemia | Endocrine/metabolic | 0.96 | 0.909 – 1.01 | 0.15 | 1468 | 14183 | all | phecode |
| 276 |
Disorders of fluid, electrolyte, and acid-baseDisorders of fluid, electrolyte, and acid-base balance
|
Endocrine/metabolic | 1.05 | 1.03 – 1.08 | 6e-05 | 9238 | 37046 | all | phecode |
| 276.1 | Electrolyte imbalance | Endocrine/metabolic | 1.04 | 1.01 – 1.07 | 0.00322 | 6352 | 34366 | all | phecode |
| 276.11 | Hyperosmolality and/or hypernatremia | Endocrine/metabolic | 1.11 | 1.01 – 1.21 | 0.0251 | 550 | 5434 | all | phecode |
| 276.12 | Hyposmolality and/or hyponatremia | Endocrine/metabolic | 1.03 | 0.992 – 1.08 | 0.117 | 2514 | 23219 | all | phecode |
| 276.13 | Hyperpotassemia | Endocrine/metabolic | 1.07 | 1.03 – 1.11 | 0.000718 | 2992 | 25216 | all | phecode |
| 276.14 | Hypopotassemia | Endocrine/metabolic | 1.01 | 0.968 – 1.06 | 0.57 | 2148 | 20909 | all | phecode |
| 276.4 | Acid-base balance disorder | Endocrine/metabolic | 1.09 | 1.04 – 1.14 | 0.000276 | 2086 | 20332 | all | phecode |
| 276.41 | Acidosis | Endocrine/metabolic | 1.08 | 1.03 – 1.14 | 0.00172 | 1788 | 17572 | all | phecode |
| 276.42 | Alkalosis | Endocrine/metabolic | 1.12 | 1.02 – 1.24 | 0.0214 | 476 | 4741 | all | phecode |
| 276.5 | Hypovolemia | Endocrine/metabolic | 1.05 | 1.02 – 1.09 | 0.00125 | 4574 | 34527 | all | phecode |
| 276.6 | Fluid overload | Endocrine/metabolic | 1.08 | 1.02 – 1.14 | 0.00777 | 1384 | 13211 | all | phecode |
| 276.8 | Polydipsia | Endocrine/metabolic | 0.977 | 0.812 – 1.17 | 0.802 | 124 | 1240 | all | phecode |
| 277 | Other disorders of metabolism | Endocrine/metabolic | 0.996 | 0.963 – 1.03 | 0.805 | 4112 | 35070 | all | phecode |
| 277.2 |
Other disorders of purine and pyrimidineOther disorders of purine and pyrimidine metabolism
|
Endocrine/metabolic | 1.03 | 0.931 – 1.15 | 0.533 | 403 | 3991 | all | phecode |
| 277.4 | Disorders of bilirubin excretion | Endocrine/metabolic | 1.03 | 0.949 – 1.11 | 0.515 | 720 | 7161 | all | phecode |
| 277.5 | Other disorders of lipoid metabolism | Endocrine/metabolic | 0.982 | 0.916 – 1.05 | 0.598 | 936 | 9270 | all | phecode |
| 277.51 | Lipoprotein disorders | Endocrine/metabolic | 1.01 | 0.94 – 1.09 | 0.729 | 773 | 7668 | all | phecode |
| 277.7 | Dysmetabolic syndrome X | Endocrine/metabolic | 0.969 | 0.904 – 1.04 | 0.381 | 916 | 8359 | all | phecode |
| 278 | Overweight, obesity and other hyperalimentation | Endocrine/metabolic | 1.06 | 1.04 – 1.08 | 1.76e-08 | 19419 | 27331 | all | phecode |
| 278.1 | Obesity | Endocrine/metabolic | 1.07 | 1.04 – 1.09 | 4.26e-10 | 17129 | 27321 | all | phecode |
| 278.11 | Morbid obesity | Endocrine/metabolic | 1.06 | 1.03 – 1.09 | 4.58e-06 | 8280 | 27172 | all | phecode |
| 278.3 | Localized adiposity | Endocrine/metabolic | 1.08 | 0.958 – 1.21 | 0.22 | 324 | 3228 | all | phecode |
| 278.4 | Abnormal weight gain | Endocrine/metabolic | 1.03 | 0.98 – 1.08 | 0.26 | 2104 | 17411 | all | phecode |
| 279 | Disorders involving the immune mechanism | Endocrine/metabolic | 1.01 | 0.97 – 1.05 | 0.663 | 2934 | 28612 | all | phecode |
| 279.1 | Immunity deficiency | Endocrine/metabolic | 1.01 | 0.95 – 1.08 | 0.734 | 1161 | 11571 | all | phecode |
| 279.11 | Deficiency of humoral immunity | Endocrine/metabolic | 0.974 | 0.868 – 1.09 | 0.651 | 330 | 3278 | all | phecode |
| 279.2 | Autoimmune disease NEC | Endocrine/metabolic | 1.02 | 0.94 – 1.1 | 0.699 | 754 | 7516 | all | phecode |
| 279.7 | Other immunological findings | Endocrine/metabolic | 1 | 0.974 – 1.04 | 0.757 | 4885 | 36552 | all | phecode |
| 279.8 |
Other specified disorders involving the immuneOther specified disorders involving the immune mechanism
|
Endocrine/metabolic | 1 | 0.92 – 1.09 | 0.954 | 601 | 5988 | all | phecode |
| 280 | Iron deficiency anemias | Hematopoietic | 1.01 | 0.977 – 1.04 | 0.605 | 4626 | 30873 | all | phecode |
| 280.1 |
Iron deficiency anemias, unspecified or not dueIron deficiency anemias, unspecified or not due to blood loss
|
Hematopoietic | 1.01 | 0.975 – 1.04 | 0.69 | 4484 | 30649 | all | phecode |
| 280.2 |
Iron deficiency anemia secondary to blood lossIron deficiency anemia secondary to blood loss (chronic)
|
Hematopoietic | 1.02 | 0.966 – 1.07 | 0.545 | 1771 | 17196 | all | phecode |
| 281 | Other deficiency anemia | Hematopoietic | 1.08 | 0.986 – 1.19 | 0.0954 | 519 | 5120 | all | phecode |
| 281.1 | Megaloblastic anemia | Hematopoietic | 1.07 | 0.943 – 1.22 | 0.282 | 253 | 2497 | all | phecode |
| 281.11 | Pernicious anemia | Hematopoietic | 1.1 | 0.911 – 1.34 | 0.313 | 114 | 1108 | all | phecode |
| 281.12 | Other vitamin B12 deficiency anemia | Hematopoietic | 1.15 | 0.987 – 1.33 | 0.0733 | 187 | 1817 | all | phecode |
| 281.9 | Deficiency anemias | Hematopoietic | 1.11 | 0.983 – 1.26 | 0.0895 | 285 | 2830 | all | phecode |
| 282 | Hereditary hemolytic anemias | Hematopoietic | 0.948 | 0.843 – 1.07 | 0.372 | 323 | 3188 | all | phecode |
| 282.8 | Other hemoglobinopathies | Hematopoietic | 0.954 | 0.827 – 1.1 | 0.517 | 216 | 2113 | all | phecode |
| 282.9 | Other hereditary hemolytic anemias | Hematopoietic | 0.969 | 0.832 – 1.13 | 0.685 | 192 | 1920 | all | phecode |
| 283 | Acquired hemolytic anemias | Hematopoietic | 0.918 | 0.776 – 1.09 | 0.321 | 155 | 1550 | all | phecode |
| 283.1 | Autoimmune hemolytic anemias | Hematopoietic | 0.967 | 0.755 – 1.24 | 0.789 | 64 | 633 | all | phecode |
| 284 | Aplastic anemia | Hematopoietic | 1.03 | 0.951 – 1.12 | 0.464 | 697 | 6943 | all | phecode |
| 284.1 | Pancytopenia | Hematopoietic | 1 | 0.922 – 1.09 | 0.923 | 612 | 6100 | all | phecode |
| 285 | Other anemias | Hematopoietic | 1.02 | 0.999 – 1.04 | 0.057 | 11794 | 33591 | all | phecode |
| 285.1 | Acute posthemorrhagic anemia | Hematopoietic | 1.03 | 0.99 – 1.07 | 0.152 | 3325 | 27709 | all | phecode |
| 285.2 | Anemia of chronic disease | Hematopoietic | 1.04 | 0.993 – 1.09 | 0.0931 | 2055 | 19939 | all | phecode |
| 285.21 | Anemia in chronic kidney disease | Hematopoietic | 1.06 | 0.992 – 1.14 | 0.0827 | 932 | 9106 | all | phecode |
| 285.22 | Anemia in neoplastic disease | Hematopoietic | 0.999 | 0.923 – 1.08 | 0.983 | 690 | 6892 | all | phecode |
| 286 | Coagulation defects | Hematopoietic | 0.984 | 0.951 – 1.02 | 0.363 | 3844 | 33384 | all | phecode |
| 286.1 | Congenital coagulation defects | Hematopoietic | 0.905 | 0.793 – 1.03 | 0.143 | 250 | 2466 | all | phecode |
| 286.11 | Von willebrand's disease | Hematopoietic | 0.764 | 0.61 – 0.957 | 0.0192 | 83 | 822 | all | phecode |
| 286.12 |
Congenital deficiency of other clotting factorsCongenital deficiency of other clotting factors (including factor VII)
|
Hematopoietic | 1.01 | 0.841 – 1.22 | 0.884 | 126 | 1260 | all | phecode |
| 286.2 |
Encounter for long-term (current) use ofEncounter for long-term (current) use of anticoagulants
|
Hematopoietic | 1.01 | 0.97 – 1.04 | 0.736 | 3354 | 25918 | all | phecode |
| 286.3 |
Coagulation defects complicating pregnancy orCoagulation defects complicating pregnancy or postpartum
|
Hematopoietic | 0.984 | 0.799 – 1.21 | 0.879 | 97 | 962 | all | phecode |
| 286.4 | Acquired coagulation factor deficiency | Hematopoietic | 1.02 | 0.889 – 1.16 | 0.814 | 254 | 2529 | all | phecode |
| 286.5 |
Hemorrhagic disorder due to intrinsicHemorrhagic disorder due to intrinsic circulating anticoagulants
|
Hematopoietic | 1.01 | 0.844 – 1.22 | 0.876 | 132 | 1294 | all | phecode |
| 286.6 | Defibrination syndrome | Hematopoietic | 0.965 | 0.926 – 1.01 | 0.0962 | 2579 | 25377 | all | phecode |
| 286.7 | Other and unspecified coagulation defects | Hematopoietic | 0.974 | 0.938 – 1.01 | 0.184 | 3014 | 29294 | all | phecode |
| 286.8 | Hypercoagulable state | Hematopoietic | 0.897 | 0.834 – 0.965 | 0.00334 | 846 | 8437 | all | phecode |
| 286.81 | Primary hypercoagulable state | Hematopoietic | 0.905 | 0.84 – 0.975 | 0.00838 | 813 | 8111 | all | phecode |
| 286.9 | Abnormal coagulation profile | Hematopoietic | 1.01 | 0.948 – 1.07 | 0.8 | 1182 | 11487 | all | phecode |
| 287 | Purpura and other hemorrhagic conditions | Hematopoietic | 0.993 | 0.957 – 1.03 | 0.72 | 3288 | 28474 | all | phecode |
| 287.1 | Spontaneous ecchymoses | Hematopoietic | 1.02 | 0.881 – 1.18 | 0.804 | 211 | 2094 | all | phecode |
| 287.3 | Thrombocytopenia | Hematopoietic | 1 | 0.964 – 1.04 | 0.893 | 2938 | 26323 | all | phecode |
| 287.31 | Primary thrombocytopenia | Hematopoietic | 0.979 | 0.899 – 1.07 | 0.624 | 601 | 5994 | all | phecode |
| 287.32 | Secondary thrombocytopenia | Hematopoietic | 0.965 | 0.884 – 1.05 | 0.429 | 569 | 5686 | all | phecode |
| 287.4 | Qualitative platelet defects | Hematopoietic | 0.994 | 0.817 – 1.21 | 0.956 | 112 | 1120 | all | phecode |
| 288 | Diseases of white blood cells | Hematopoietic | 1.05 | 1.02 – 1.08 | 0.00351 | 4886 | 36527 | all | phecode |
| 288.1 | Decreased white blood cell count | Hematopoietic | 0.976 | 0.926 – 1.03 | 0.359 | 1599 | 15951 | all | phecode |
| 288.11 | Neutropenia | Hematopoietic | 0.976 | 0.916 – 1.04 | 0.449 | 1106 | 11041 | all | phecode |
| 288.2 | Elevated white blood cell count | Hematopoietic | 1.06 | 1.03 – 1.1 | 0.000606 | 4082 | 35079 | all | phecode |
| 288.3 | Eosinophilia | Hematopoietic | 0.853 | 0.734 – 0.992 | 0.0386 | 187 | 1866 | all | phecode |
| 289 | Other diseases of blood and blood-forming organs | Hematopoietic | 0.93 | 0.884 – 0.978 | 0.00468 | 1757 | 17434 | all | phecode |
| 289.3 |
Personal history of diseases of blood andPersonal history of diseases of blood and blood-forming organs
|
Hematopoietic | 0.923 | 0.861 – 0.99 | 0.0253 | 918 | 9087 | all | phecode |
| 289.4 | Lymphadenitis | Hematopoietic | 1.02 | 0.985 – 1.05 | 0.283 | 3888 | 34715 | all | phecode |
| 289.5 | Diseases of spleen | Hematopoietic | 0.99 | 0.892 – 1.1 | 0.85 | 393 | 3913 | all | phecode |
| 289.8 | Polycythemia, secondary | Hematopoietic | 0.971 | 0.851 – 1.11 | 0.658 | 255 | 2550 | all | phecode |
| 289.9 | Abnormality of red blood cells | Hematopoietic | 0.949 | 0.852 – 1.06 | 0.336 | 385 | 3813 | all | phecode |
| 290 |
Delirium dementia and amnestic and otherDelirium dementia and amnestic and other cognitive disorders
|
Mental Disorders | 1.05 | 0.989 – 1.11 | 0.111 | 1318 | 11547 | all | phecode |
| 290.1 | Dementias | Mental Disorders | 0.942 | 0.86 – 1.03 | 0.203 | 541 | 4910 | all | phecode |
| 290.11 | Alzheimer's disease | Mental Disorders | 0.806 | 0.678 – 0.958 | 0.0143 | 151 | 1389 | all | phecode |
| 290.12 | Dementia with cerebral degenerations | Mental Disorders | 0.77 | 0.615 – 0.964 | 0.0225 | 88 | 846 | all | phecode |
| 290.13 | Senile dementia | Mental Disorders | 0.919 | 0.819 – 1.03 | 0.155 | 340 | 3078 | all | phecode |
| 290.16 | Vascular dementia | Mental Disorders | 1.12 | 0.878 – 1.42 | 0.366 | 81 | 777 | all | phecode |
| 290.2 | Delirium due to conditions classified elsewhere | Mental Disorders | 1.11 | 1.03 – 1.2 | 0.00863 | 750 | 7358 | all | phecode |
| 290.3 |
Other persistent mental disorders due toOther persistent mental disorders due to conditions classified elsewhere
|
Mental Disorders | 0.949 | 0.883 – 1.02 | 0.148 | 886 | 8618 | all | phecode |
| 291 |
Other specified nonpsychotic and/or transientOther specified nonpsychotic and/or transient mental disorders
|
Mental Disorders | 1.02 | 0.978 – 1.06 | 0.35 | 2550 | 24810 | all | phecode |
| 291.1 |
Transient mental disorders due to conditionsTransient mental disorders due to conditions classified elsewhere
|
Mental Disorders | 1.04 | 0.894 – 1.22 | 0.585 | 175 | 1750 | all | phecode |
| 291.4 |
Specific nonpsychotic mental disorders due toSpecific nonpsychotic mental disorders due to brain damage
|
Mental Disorders | 1.02 | 0.925 – 1.12 | 0.713 | 484 | 4807 | all | phecode |
| 291.8 | Alteration of consciousness | Mental Disorders | 1.03 | 0.979 – 1.08 | 0.276 | 2036 | 19974 | all | phecode |
| 292 | Neurological disorders | Mental Disorders | 0.997 | 0.968 – 1.03 | 0.819 | 5733 | 38553 | all | phecode |
| 292.1 | Aphasia/speech disturbance | Mental Disorders | 0.99 | 0.944 – 1.04 | 0.678 | 2013 | 19867 | all | phecode |
| 292.11 | Aphasia | Mental Disorders | 0.954 | 0.879 – 1.04 | 0.264 | 664 | 6581 | all | phecode |
| 292.12 | Symbolic dysfunction | Mental Disorders | 0.904 | 0.778 – 1.05 | 0.19 | 200 | 1988 | all | phecode |
| 292.2 | Mild cognitive impairment | Mental Disorders | 0.993 | 0.892 – 1.11 | 0.896 | 389 | 3731 | all | phecode |
| 292.3 | Memory loss | Mental Disorders | 0.969 | 0.924 – 1.02 | 0.21 | 1922 | 18158 | all | phecode |
| 292.4 | Altered mental status | Mental Disorders | 1.06 | 1.02 – 1.11 | 0.00782 | 2454 | 22725 | all | phecode |
| 292.5 | Transient alteration of awareness | Mental Disorders | 1.12 | 1.01 – 1.24 | 0.0376 | 430 | 4285 | all | phecode |
| 292.6 | Hallucinations | Mental Disorders | 0.994 | 0.863 – 1.14 | 0.93 | 217 | 2147 | all | phecode |
| 293 | Symptoms involving head and neck | Mental Disorders | 0.969 | 0.874 – 1.07 | 0.55 | 414 | 4127 | all | phecode |
| 293.1 |
Swelling, mass, or lump in head and neckSwelling, mass, or lump in head and neck [Space-occupying lesion, intracranial NOS]
|
Mental Disorders | 1 | 0.972 – 1.04 | 0.812 | 4417 | 38609 | all | phecode |
| 295 | Schizophrenia and other psychotic disorders | Mental Disorders | 1.08 | 1.01 – 1.16 | 0.0344 | 885 | 8229 | all | phecode |
| 295.1 | Schizophrenia | Mental Disorders | 1.04 | 0.865 – 1.24 | 0.693 | 138 | 1339 | all | phecode |
| 295.2 | Paranoid disorders | Mental Disorders | 0.956 | 0.788 – 1.16 | 0.647 | 118 | 1079 | all | phecode |
| 295.3 | Psychosis | Mental Disorders | 1.13 | 1.04 – 1.22 | 0.00318 | 716 | 6694 | all | phecode |
| 296 | Mood disorders | Mental Disorders | 1.08 | 1.06 – 1.11 | 2.92e-12 | 15356 | 20858 | all | phecode |
| 296.1 | Bipolar | Mental Disorders | 1.13 | 1.06 – 1.19 | 0.000104 | 1301 | 11264 | all | phecode |
| 296.2 | Depression | Mental Disorders | 1.08 | 1.06 – 1.1 | 8.04e-12 | 14833 | 20856 | all | phecode |
| 296.22 | Major depressive disorder | Mental Disorders | 1.08 | 1.06 – 1.11 | 6.36e-12 | 13850 | 20853 | all | phecode |
| 297 | Suicidal ideation or attempt | Mental Disorders | 1.17 | 1.1 – 1.26 | 5.41e-06 | 985 | 9050 | all | phecode |
| 297.1 | Suicidal ideation | Mental Disorders | 1.18 | 1.09 – 1.27 | 3.26e-05 | 788 | 7310 | all | phecode |
| 297.2 | Suicide or self-inflicted injury | Mental Disorders | 1.16 | 1.02 – 1.32 | 0.0225 | 285 | 2654 | all | phecode |
| 300 | Anxiety disorders | Mental Disorders | 1.07 | 1.05 – 1.1 | 3.61e-10 | 15419 | 20850 | all | phecode |
| 300.1 | Anxiety disorder | Mental Disorders | 1.07 | 1.05 – 1.1 | 1.23e-09 | 14517 | 20855 | all | phecode |
| 300.11 | Generalized anxiety disorder | Mental Disorders | 1.05 | 1.02 – 1.09 | 0.00126 | 5546 | 20512 | all | phecode |
| 300.12 | Agorophobia, social phobia, and panic disorder | Mental Disorders | 1.12 | 1.05 – 1.19 | 0.000264 | 1360 | 11377 | all | phecode |
| 300.13 | Phobia | Mental Disorders | 1.07 | 1 – 1.15 | 0.0371 | 1051 | 9542 | all | phecode |
| 300.3 | Obsessive-compulsive disorders | Mental Disorders | 0.921 | 0.819 – 1.03 | 0.165 | 328 | 3018 | all | phecode |
| 300.4 | Dysthymic disorder | Mental Disorders | 1.1 | 1.05 – 1.15 | 6.17e-05 | 2420 | 16552 | all | phecode |
| 300.8 | Acute reaction to stress | Mental Disorders | 1.06 | 0.967 – 1.17 | 0.201 | 504 | 4825 | all | phecode |
| 300.9 | Posttraumatic stress disorder | Mental Disorders | 1.26 | 1.17 – 1.36 | 1.61e-09 | 843 | 7909 | all | phecode |
| 301 | Personality disorders | Mental Disorders | 1.22 | 1.11 – 1.35 | 7.16e-05 | 477 | 4539 | all | phecode |
| 301.2 | Antisocial/borderline personality disorder | Mental Disorders | 1.15 | 1.01 – 1.32 | 0.0382 | 254 | 2393 | all | phecode |
| 302 | Sexual and gender identity disorders | Mental Disorders | 0.979 | 0.943 – 1.02 | 0.283 | 3700 | 13808 | all | phecode |
| 302.1 | Decreased libido | Mental Disorders | 1 | 0.908 – 1.11 | 0.926 | 447 | 4331 | all | phecode |
| 303 | Psychogenic and somatoform disorders | Mental Disorders | 0.965 | 0.937 – 0.993 | 0.0139 | 6808 | 20043 | all | phecode |
| 303.1 | Dissociative disorder | Mental Disorders | 1.03 | 0.876 – 1.22 | 0.696 | 161 | 1573 | all | phecode |
| 303.3 | Psychogenic disorder | Mental Disorders | 0.957 | 0.929 – 0.986 | 0.00335 | 6487 | 19888 | all | phecode |
| 303.31 |
Gastrointestinal malfunction arising fromGastrointestinal malfunction arising from mental factors
|
Mental Disorders | 0.98 | 0.889 – 1.08 | 0.677 | 471 | 4623 | all | phecode |
| 303.4 | Somatoform disorder | Mental Disorders | 0.985 | 0.926 – 1.05 | 0.632 | 1177 | 11180 | all | phecode |
| 304 | Adjustment reaction | Mental Disorders | 1.06 | 1.03 – 1.1 | 0.000733 | 3888 | 20475 | all | phecode |
| 305.2 | Eating disorder | Mental Disorders | 1.08 | 1 – 1.15 | 0.0415 | 901 | 8329 | all | phecode |
| 306 | Other mental disorder | Mental Disorders | 1.06 | 1 – 1.11 | 0.0321 | 1815 | 14133 | all | phecode |
| 306.1 | Mental disorders durring/after pregnancy | Mental Disorders | 1.1 | 1 – 1.21 | 0.0397 | 587 | 3527 | all | phecode |
| 306.9 | Tension headache | Mental Disorders | 1.06 | 0.979 – 1.14 | 0.155 | 753 | 7277 | all | phecode |
| 312 | Conduct disorders | Mental Disorders | 1.2 | 1.05 – 1.37 | 0.0063 | 254 | 2501 | all | phecode |
| 312.3 | Impulse control disorder | Mental Disorders | 1.27 | 1 – 1.62 | 0.0467 | 74 | 736 | all | phecode |
| 313 | Pervasive developmental disorders | Mental Disorders | 1.03 | 0.981 – 1.09 | 0.213 | 1571 | 14633 | all | phecode |
| 313.1 | Attention deficit hyperactivity disorder | Mental Disorders | 1.03 | 0.977 – 1.09 | 0.256 | 1392 | 13190 | all | phecode |
| 313.2 | Tics and stuttering | Mental Disorders | 1.22 | 0.96 – 1.56 | 0.103 | 77 | 770 | all | phecode |
| 313.3 | Autism | Mental Disorders | 1.18 | 0.91 – 1.54 | 0.209 | 64 | 621 | all | phecode |
| 315 | Develomental delays and disorders | Mental Disorders | 0.986 | 0.91 – 1.07 | 0.725 | 684 | 6788 | all | phecode |
| 315.1 | Learning disorder | Mental Disorders | 0.823 | 0.656 – 1.03 | 0.0934 | 87 | 860 | all | phecode |
| 315.2 | Speech and language disorder | Mental Disorders | 0.885 | 0.774 – 1.01 | 0.0734 | 254 | 2539 | all | phecode |
| 316 | Substance addiction and disorders | Mental Disorders | 1.23 | 1.18 – 1.27 | 9.23e-30 | 3682 | 32680 | all | phecode |
| 316.1 | Polyneuropathy due to drugs | Mental Disorders | 1 | 0.919 – 1.09 | 0.995 | 634 | 6331 | all | phecode |
| 317 | Alcohol-related disorders | Mental Disorders | 1.23 | 1.18 – 1.28 | 1.78e-21 | 2525 | 22920 | all | phecode |
| 317.1 | Alcoholism | Mental Disorders | 1.21 | 1.16 – 1.27 | 2.75e-15 | 1986 | 19339 | all | phecode |
| 317.11 | Alcoholic liver damage | Mental Disorders | 1.14 | 1.03 – 1.27 | 0.0145 | 408 | 4080 | all | phecode |
| 318 | Tobacco use disorder | Mental Disorders | 1.31 | 1.28 – 1.34 | 3.31e-103 | 8622 | 34842 | all | phecode |
| 320 | Meningitis | Neurological | 1.02 | 0.916 – 1.13 | 0.72 | 382 | 3820 | all | phecode |
| 323 | Encephalitis | Neurological | 1.04 | 0.893 – 1.22 | 0.6 | 181 | 1809 | all | phecode |
| 323.8 | Encephalitis, non-infectious | Neurological | 1.01 | 0.856 – 1.2 | 0.892 | 153 | 1527 | all | phecode |
| 324 | Other CNS infection and poliomyelitis | Neurological | 1.12 | 0.985 – 1.26 | 0.0843 | 288 | 2880 | all | phecode |
| 325 |
Phlebitis and thrombophlebitis of intracranialPhlebitis and thrombophlebitis of intracranial venous sinuses
|
Neurological | 1.17 | 0.874 – 1.56 | 0.295 | 53 | 530 | all | phecode |
| 327 | Sleep disorders | Neurological | 1.03 | 1.01 – 1.05 | 0.00159 | 14941 | 31602 | all | phecode |
| 327.1 | Hypersomnia | Neurological | 0.965 | 0.921 – 1.01 | 0.13 | 2061 | 19110 | all | phecode |
| 327.3 | Sleep apnea | Neurological | 1.04 | 1.01 – 1.06 | 0.00187 | 10909 | 31304 | all | phecode |
| 327.31 | Central/nonobstroctive sleep apnea | Neurological | 0.981 | 0.893 – 1.08 | 0.689 | 492 | 4784 | all | phecode |
| 327.32 | Obstructive sleep apnea | Neurological | 1.02 | 0.999 – 1.05 | 0.0557 | 8744 | 30530 | all | phecode |
| 327.4 | Insomnia | Neurological | 1.04 | 1.01 – 1.07 | 0.0156 | 5524 | 30960 | all | phecode |
| 327.41 | Organic or persistent insomnia | Neurological | 1 | 0.943 – 1.06 | 0.979 | 1265 | 12120 | all | phecode |
| 327.5 | Parasomnia | Neurological | 1.04 | 0.959 – 1.14 | 0.318 | 604 | 5913 | all | phecode |
| 327.6 | Circadian rhythm sleep disorder | Neurological | 1.06 | 0.931 – 1.2 | 0.392 | 274 | 2666 | all | phecode |
| 327.7 | Sleep related movement disorders | Neurological | 1.03 | 0.982 – 1.09 | 0.213 | 1786 | 17323 | all | phecode |
| 327.71 | Restless legs syndrome | Neurological | 1.04 | 0.982 – 1.09 | 0.192 | 1570 | 15360 | all | phecode |
| 327.72 | Sleep related leg cramps | Neurological | 1.04 | 0.831 – 1.31 | 0.714 | 83 | 822 | all | phecode |
| 331 | Other cerebral degenerations | Neurological | 1 | 0.925 – 1.08 | 0.965 | 717 | 7024 | all | phecode |
| 331.1 | Hydrocephalus | Neurological | 0.979 | 0.864 – 1.11 | 0.74 | 284 | 2836 | all | phecode |
| 331.9 | Cerebral degeneration, unspecified | Neurological | 0.991 | 0.893 – 1.1 | 0.859 | 419 | 4026 | all | phecode |
| 332 | Parkinson's disease | Neurological | 0.915 | 0.825 – 1.02 | 0.0935 | 415 | 4128 | all | phecode |
| 333 |
Extrapyramidal disease and abnormal movementExtrapyramidal disease and abnormal movement disorders
|
Neurological | 1.02 | 0.98 – 1.06 | 0.328 | 2868 | 26583 | all | phecode |
| 333.1 | Essential tremor | Neurological | 0.952 | 0.88 – 1.03 | 0.216 | 725 | 7163 | all | phecode |
| 333.2 | Myoclonus | Neurological | 0.995 | 0.84 – 1.18 | 0.951 | 159 | 1590 | all | phecode |
| 333.4 | Torsion dystonia | Neurological | 0.904 | 0.808 – 1.01 | 0.079 | 352 | 3504 | all | phecode |
| 333.8 | Other degenerative diseases of the basal ganglia | Neurological | 0.981 | 0.786 – 1.22 | 0.867 | 89 | 890 | all | phecode |
| 334 | Degenerative disease of the spinal cord | Neurological | 1.05 | 0.981 – 1.12 | 0.165 | 1058 | 10562 | all | phecode |
| 334.1 | Spinocerebellar disease | Neurological | 0.902 | 0.716 – 1.14 | 0.381 | 79 | 790 | all | phecode |
| 334.2 | Anterior horn cell disease | Neurological | 0.855 | 0.698 – 1.05 | 0.127 | 110 | 1080 | all | phecode |
| 334.21 | Amyotrophic Lateral Sclerosis | Neurological | 0.877 | 0.678 – 1.13 | 0.316 | 71 | 693 | all | phecode |
| 335 | Multiple sclerosis | Neurological | 1.09 | 0.982 – 1.21 | 0.105 | 396 | 3951 | all | phecode |
| 337 | Disorders of the autonomic nervous system | Neurological | 0.965 | 0.895 – 1.04 | 0.346 | 808 | 7413 | all | phecode |
| 337.1 | Peripheral autonomic neuropathy | Neurological | 0.919 | 0.823 – 1.03 | 0.133 | 370 | 3164 | all | phecode |
| 338 | Pain | Neurological | 1.06 | 1.04 – 1.08 | 1.52e-08 | 20346 | 26417 | all | phecode |
| 338.1 | Acute pain | Neurological | 1.06 | 1.04 – 1.08 | 9.42e-08 | 15582 | 26313 | all | phecode |
| 338.2 | Chronic pain | Neurological | 1.08 | 1.05 – 1.1 | 4.7e-10 | 10994 | 26368 | all | phecode |
| 339 | Other headache syndromes | Neurological | 1.03 | 1.01 – 1.06 | 0.00821 | 9242 | 34658 | all | phecode |
| 340 | Migraine | Neurological | 1 | 0.977 – 1.03 | 0.766 | 6708 | 30587 | all | phecode |
| 340.1 | Migrain with aura | Neurological | 1.01 | 0.971 – 1.04 | 0.73 | 3624 | 23684 | all | phecode |
| 341 |
Other demyelinating diseases of central nervousOther demyelinating diseases of central nervous system
|
Neurological | 1.01 | 0.835 – 1.21 | 0.945 | 133 | 1330 | all | phecode |
| 342 | Hemiplegia | Neurological | 0.997 | 0.904 – 1.1 | 0.954 | 464 | 4607 | all | phecode |
| 343 | Infantile cerebral palsy | Neurological | 1.1 | 0.876 – 1.37 | 0.421 | 85 | 847 | all | phecode |
| 344 | Other paralytic syndromes | Neurological | 1.01 | 0.928 – 1.09 | 0.86 | 682 | 6808 | all | phecode |
| 345 | Epilepsy, recurrent seizures, convulsions | Neurological | 1.03 | 0.992 – 1.08 | 0.115 | 2553 | 25307 | all | phecode |
| 345.1 | Epilepsy | Neurological | 1.01 | 0.934 – 1.09 | 0.83 | 747 | 7465 | all | phecode |
| 345.11 | Generalized convulsive epilepsy | Neurological | 0.973 | 0.849 – 1.12 | 0.696 | 233 | 2330 | all | phecode |
| 345.12 | Partial epilepsy | Neurological | 1.01 | 0.927 – 1.11 | 0.755 | 534 | 5335 | all | phecode |
| 345.3 | Convulsions | Neurological | 1.03 | 0.99 – 1.08 | 0.129 | 2396 | 23796 | all | phecode |
| 346 |
Abnormal findings on study of brain and/orAbnormal findings on study of brain and/or nervous system
|
Neurological | 1.07 | 0.921 – 1.25 | 0.364 | 183 | 1824 | all | phecode |
| 346.1 |
Nonspecific abnormal findings on radiologicalNonspecific abnormal findings on radiological and other examination of skull and head
|
Neurological | 1.01 | 0.952 – 1.06 | 0.828 | 1472 | 14587 | all | phecode |
| 346.2 |
Nonspecific abnormal results of function studyNonspecific abnormal results of function study of brain and central nervous system
|
Neurological | 1.08 | 0.896 – 1.31 | 0.407 | 120 | 1181 | all | phecode |
| 346.3 |
Nonspecific abnormal findings in cerebrospinalNonspecific abnormal findings in cerebrospinal fluid
|
Neurological | 1.15 | 0.94 – 1.4 | 0.178 | 110 | 1100 | all | phecode |
| 347 | Cataplexy and narcolepsy | Neurological | 1.02 | 0.828 – 1.26 | 0.853 | 101 | 1010 | all | phecode |
| 348 | Other conditions of brain | Neurological | 1.04 | 0.99 – 1.09 | 0.115 | 1793 | 17894 | all | phecode |
| 348.2 | Cerebral edema and compression of brain | Neurological | 1.01 | 0.941 – 1.08 | 0.787 | 905 | 9034 | all | phecode |
| 348.4 | Cerebral cysts | Neurological | 0.937 | 0.816 – 1.08 | 0.359 | 229 | 2290 | all | phecode |
| 348.7 | Coma | Neurological | 0.989 | 0.861 – 1.14 | 0.876 | 229 | 2275 | all | phecode |
| 348.8 | Encephalopathy, not elsewhere classified | Neurological | 1.09 | 1.01 – 1.17 | 0.0191 | 853 | 8479 | all | phecode |
| 348.9 | Other conditions of brain, NOS | Neurological | 1.01 | 0.97 – 1.06 | 0.567 | 2341 | 23287 | all | phecode |
| 349 |
Other and unspecified disorders of the nervousOther and unspecified disorders of the nervous system
|
Neurological | 1.05 | 0.98 – 1.12 | 0.166 | 941 | 9385 | all | phecode |
| 350 | Abnormal movement | Neurological | 0.987 | 0.96 – 1.01 | 0.331 | 6706 | 38762 | all | phecode |
| 350.1 | Abnormal involuntary movements | Neurological | 0.98 | 0.944 – 1.02 | 0.284 | 3273 | 30524 | all | phecode |
| 350.2 | Abnormality of gait | Neurological | 0.995 | 0.961 – 1.03 | 0.777 | 3920 | 30520 | all | phecode |
| 350.3 | Lack of coordination | Neurological | 0.994 | 0.932 – 1.06 | 0.866 | 1062 | 10554 | all | phecode |
| 350.5 | Abnormal reflex | Neurological | 0.977 | 0.845 – 1.13 | 0.752 | 200 | 1988 | all | phecode |
| 350.6 | Disturbances of sensation of smell and taste | Neurological | 0.977 | 0.893 – 1.07 | 0.603 | 558 | 5576 | all | phecode |
| 351 | Other peripheral nerve disorders | Neurological | 1.05 | 1.02 – 1.07 | 0.000825 | 7401 | 34460 | all | phecode |
| 352 | Disorders of other cranial nerves | Neurological | 0.975 | 0.926 – 1.03 | 0.322 | 1714 | 17106 | all | phecode |
| 352.1 | Trigeminal nerve disorders [CN5] | Neurological | 0.991 | 0.906 – 1.08 | 0.848 | 535 | 5344 | all | phecode |
| 352.2 | Facial nerve disorders [CN7] | Neurological | 0.983 | 0.912 – 1.06 | 0.657 | 783 | 7826 | all | phecode |
| 353 | Nerve root and plexus disorders | Neurological | 1.06 | 1.03 – 1.1 | 0.00021 | 4256 | 33369 | all | phecode |
| 353.1 | Nerve plexus lesions | Neurological | 1.06 | 0.951 – 1.17 | 0.305 | 390 | 3900 | all | phecode |
| 353.2 | Nerve root lesions | Neurological | 1.27 | 1.06 – 1.52 | 0.0104 | 130 | 1287 | all | phecode |
| 355 | Complex regional/central pain syndrome | Neurological | 1.08 | 0.988 – 1.19 | 0.0905 | 531 | 5295 | all | phecode |
| 355.1 | Chronic pain syndrome | Neurological | 1.14 | 1.06 – 1.23 | 0.000286 | 843 | 8386 | all | phecode |
| 356 | Hereditary and idiopathic peripheral neuropathy | Neurological | 1 | 0.961 – 1.05 | 0.839 | 2335 | 20731 | all | phecode |
| 357 | Inflammatory and toxic neuropathy | Neurological | 1.01 | 0.976 – 1.05 | 0.501 | 3472 | 29956 | all | phecode |
| 358 | Myoneural disorders | Neurological | 1.06 | 0.997 – 1.13 | 0.0637 | 1147 | 11391 | all | phecode |
| 358.1 | Myasthenia gravis | Neurological | 1.06 | 0.865 – 1.29 | 0.593 | 109 | 1082 | all | phecode |
| 359 | Muscular dystrophies and other myopathies | Neurological | 0.988 | 0.928 – 1.05 | 0.702 | 1134 | 11274 | all | phecode |
| 359.1 | Muscular dystrophies | Neurological | 1.08 | 0.825 – 1.41 | 0.58 | 64 | 632 | all | phecode |
| 359.2 | Myopathy | Neurological | 0.983 | 0.922 – 1.05 | 0.6 | 1092 | 10843 | all | phecode |
| 360 | Disorders of the globe | Sense Organs | 0.974 | 0.809 – 1.17 | 0.777 | 131 | 1276 | all | phecode |
| 360.2 | Progressive myopia | Sense Organs | 0.837 | 0.648 – 1.08 | 0.174 | 65 | 640 | all | phecode |
| 361 | Retinal detachments and defects | Sense Organs | 0.963 | 0.89 – 1.04 | 0.342 | 733 | 7131 | all | phecode |
| 361.1 | Retinal detachment with retinal defect | Sense Organs | 0.918 | 0.813 – 1.04 | 0.17 | 302 | 2962 | all | phecode |
| 362 | Other retinal disorders | Sense Organs | 0.959 | 0.924 – 0.995 | 0.0267 | 3569 | 22997 | all | phecode |
| 362.2 |
Degeneration of macula and posterior pole ofDegeneration of macula and posterior pole of retina
|
Sense Organs | 0.97 | 0.926 – 1.02 | 0.202 | 2172 | 15483 | all | phecode |
| 362.21 | Macular degeneration, dry | Sense Organs | 0.956 | 0.861 – 1.06 | 0.394 | 419 | 3438 | all | phecode |
| 362.22 | Macular degeneration, wet | Sense Organs | 1.03 | 0.862 – 1.24 | 0.73 | 148 | 1184 | all | phecode |
| 362.23 | Cystoid macular degeneration of retina | Sense Organs | 0.964 | 0.867 – 1.07 | 0.495 | 408 | 3839 | all | phecode |
| 362.26 | Macular puckering of retina | Sense Organs | 0.947 | 0.885 – 1.01 | 0.12 | 976 | 8610 | all | phecode |
| 362.27 | Drusen (degenerative) of retina | Sense Organs | 0.915 | 0.831 – 1.01 | 0.0698 | 488 | 4558 | all | phecode |
| 362.29 | Macular degeneration (senile) of retina NOS | Sense Organs | 0.988 | 0.939 – 1.04 | 0.628 | 1883 | 13955 | all | phecode |
| 362.3 | Other nondiabetic retinopathy | Sense Organs | 0.984 | 0.92 – 1.05 | 0.653 | 976 | 8527 | all | phecode |
| 362.31 | Separation of retinal layers | Sense Organs | 0.979 | 0.883 – 1.09 | 0.692 | 413 | 4056 | all | phecode |
| 362.4 | Retinal vascular changes and abnomalities | Sense Organs | 0.983 | 0.904 – 1.07 | 0.681 | 662 | 5933 | all | phecode |
| 362.6 | Peripheral retinal degenerations | Sense Organs | 0.947 | 0.852 – 1.05 | 0.311 | 392 | 3787 | all | phecode |
| 362.7 | Hereditary retinal dystrophies | Sense Organs | 0.979 | 0.848 – 1.13 | 0.766 | 215 | 2103 | all | phecode |
| 362.8 | Retinal hemorrhage/ischemia | Sense Organs | 1.02 | 0.889 – 1.17 | 0.79 | 241 | 2368 | all | phecode |
| 362.9 | Retinal edema | Sense Organs | 0.926 | 0.823 – 1.04 | 0.2 | 324 | 2936 | all | phecode |
| 363 |
Chorioretinal inflammations, scars, and otherChorioretinal inflammations, scars, and other disorders of choroid
|
Sense Organs | 0.976 | 0.887 – 1.07 | 0.623 | 492 | 4746 | all | phecode |
| 363.3 | Chorioretinal scars | Sense Organs | 0.911 | 0.811 – 1.02 | 0.119 | 332 | 3184 | all | phecode |
| 364 | Corneal opacity and other disorders of cornea | Sense Organs | 0.93 | 0.874 – 0.991 | 0.0239 | 1132 | 10772 | all | phecode |
| 364.1 | Corneal opacity | Sense Organs | 1.02 | 0.917 – 1.14 | 0.715 | 394 | 3846 | all | phecode |
| 364.2 | Corneal edema | Sense Organs | 0.947 | 0.784 – 1.14 | 0.568 | 123 | 1208 | all | phecode |
| 364.4 | Corneal degenerations | Sense Organs | 0.916 | 0.826 – 1.02 | 0.0969 | 402 | 3962 | all | phecode |
| 364.41 | Keratoconus | Sense Organs | 0.893 | 0.703 – 1.13 | 0.352 | 75 | 739 | all | phecode |
| 364.5 | Corneal dystrophy | Sense Organs | 0.875 | 0.796 – 0.962 | 0.0058 | 502 | 4682 | all | phecode |
| 364.51 | Fuchs' dystrophy | Sense Organs | 0.835 | 0.733 – 0.95 | 0.00604 | 266 | 2521 | all | phecode |
| 364.9 | Cornea replaced by transplant | Sense Organs | 0.876 | 0.696 – 1.1 | 0.26 | 91 | 885 | all | phecode |
| 365 | Glaucoma | Sense Organs | 0.934 | 0.896 – 0.974 | 0.00146 | 2672 | 21326 | all | phecode |
| 365.1 | Open-angle glaucoma | Sense Organs | 0.913 | 0.844 – 0.988 | 0.0241 | 705 | 6491 | all | phecode |
| 365.11 | Primary open angle glaucoma | Sense Organs | 0.876 | 0.79 – 0.972 | 0.0124 | 403 | 3681 | all | phecode |
| 365.2 | Primary angle-closure glaucoma | Sense Organs | 1.08 | 0.949 – 1.23 | 0.241 | 251 | 2370 | all | phecode |
| 366 | Cataract | Sense Organs | 0.972 | 0.946 – 0.998 | 0.0341 | 8611 | 28043 | all | phecode |
| 366.1 | Nonsenile Cataract | Sense Organs | 0.925 | 0.799 – 1.07 | 0.294 | 207 | 1979 | all | phecode |
| 366.2 | Senile cataract | Sense Organs | 0.966 | 0.935 – 0.997 | 0.0306 | 5480 | 24980 | all | phecode |
| 367 |
Disorders of refraction and accommodationDisorders of refraction and accommodation; blindness and low vision
|
Sense Organs | 0.965 | 0.942 – 0.988 | 0.00369 | 8967 | 37779 | all | phecode |
| 367.1 | Myopia | Sense Organs | 0.936 | 0.907 – 0.965 | 2.88e-05 | 5014 | 34677 | all | phecode |
| 367.2 | Astigmatism | Sense Organs | 0.943 | 0.912 – 0.976 | 0.000663 | 4161 | 32463 | all | phecode |
| 367.8 | Hypermetropia | Sense Organs | 0.965 | 0.921 – 1.01 | 0.146 | 2039 | 18599 | all | phecode |
| 367.9 | Blindness and low vision | Sense Organs | 1.04 | 0.982 – 1.11 | 0.179 | 1277 | 12356 | all | phecode |
| 368 | Visual disturbances | Sense Organs | 1 | 0.974 – 1.03 | 0.886 | 5715 | 39599 | all | phecode |
| 368.1 | Amblyopia | Sense Organs | 0.962 | 0.886 – 1.05 | 0.362 | 651 | 6479 | all | phecode |
| 368.2 | Diplopia and disorders of binocular vision | Sense Organs | 0.98 | 0.919 – 1.05 | 0.541 | 1087 | 10786 | all | phecode |
| 368.3 | Anisometropia | Sense Organs | 0.944 | 0.819 – 1.09 | 0.421 | 219 | 2168 | all | phecode |
| 368.4 | Visual field defects | Sense Organs | 1.03 | 0.97 – 1.1 | 0.315 | 1132 | 11173 | all | phecode |
| 368.9 | Subjective visual disturbances | Sense Organs | 0.984 | 0.922 – 1.05 | 0.636 | 1070 | 10620 | all | phecode |
| 368.91 | Psychophysical visual disturbances | Sense Organs | 0.862 | 0.714 – 1.04 | 0.119 | 120 | 1171 | all | phecode |
| 369 | Infection of the eye | Sense Organs | 0.93 | 0.896 – 0.966 | 0.000177 | 3185 | 28240 | all | phecode |
| 369.2 | Eye infection, viral | Sense Organs | 0.911 | 0.83 – 1 | 0.0507 | 502 | 4954 | all | phecode |
| 369.5 | Conjunctivitis, infectious | Sense Organs | 0.919 | 0.883 – 0.958 | 5.37e-05 | 2716 | 24970 | all | phecode |
| 370 | Keratitis | Sense Organs | 0.943 | 0.891 – 0.998 | 0.0431 | 1365 | 13169 | all | phecode |
| 370.1 | Corneal ulcer | Sense Organs | 0.985 | 0.857 – 1.13 | 0.836 | 223 | 2194 | all | phecode |
| 370.2 | Superficial keratitis | Sense Organs | 0.934 | 0.854 – 1.02 | 0.131 | 546 | 5393 | all | phecode |
| 370.3 | Keratoconjunctivitis | Sense Organs | 0.894 | 0.822 – 0.971 | 0.00792 | 649 | 6263 | all | phecode |
| 370.31 | Keratoconjunctivitis sicca | Sense Organs | 0.779 | 0.667 – 0.91 | 0.00161 | 179 | 1677 | all | phecode |
| 371 | Inflammation of the eye | Sense Organs | 0.957 | 0.926 – 0.989 | 0.0086 | 4414 | 32310 | all | phecode |
| 371.1 | Uveitis, noninfectious or NOS | Sense Organs | 0.987 | 0.902 – 1.08 | 0.775 | 541 | 5278 | all | phecode |
| 371.2 | Conjunctivitis, noninfectious | Sense Organs | 0.971 | 0.905 – 1.04 | 0.4 | 906 | 8939 | all | phecode |
| 371.21 | Allergic conjunctivitis | Sense Organs | 0.967 | 0.896 – 1.04 | 0.393 | 756 | 7515 | all | phecode |
| 371.3 | Inflammation of eyelids | Sense Organs | 0.947 | 0.913 – 0.983 | 0.00389 | 3398 | 26983 | all | phecode |
| 371.33 | Noninfectious dermatoses of eyelid | Sense Organs | 0.93 | 0.773 – 1.12 | 0.443 | 133 | 1291 | all | phecode |
| 372 | Disorders of conjunctiva | Sense Organs | 0.961 | 0.901 – 1.02 | 0.222 | 1118 | 10728 | all | phecode |
| 374 | Other disorders of eyelids | Sense Organs | 0.986 | 0.947 – 1.03 | 0.47 | 2940 | 24188 | all | phecode |
| 374.1 | Ectropion or entropion | Sense Organs | 0.953 | 0.86 – 1.05 | 0.35 | 431 | 4084 | all | phecode |
| 374.2 | Lagophthalmos | Sense Organs | 1.07 | 0.933 – 1.23 | 0.335 | 235 | 2335 | all | phecode |
| 374.3 | Ptosis of eyelid | Sense Organs | 1.02 | 0.953 – 1.08 | 0.643 | 1102 | 10734 | all | phecode |
| 374.6 | Dermatochalasis | Sense Organs | 1.01 | 0.945 – 1.08 | 0.775 | 1040 | 9720 | all | phecode |
| 375 | Disorders of lacrimal system | Sense Organs | 0.951 | 0.918 – 0.986 | 0.00644 | 3694 | 26045 | all | phecode |
| 375.1 | Dry eyes | Sense Organs | 0.939 | 0.907 – 0.972 | 0.000345 | 4040 | 26751 | all | phecode |
| 375.2 | Epiphora | Sense Organs | 1.06 | 0.955 – 1.17 | 0.285 | 442 | 4354 | all | phecode |
| 376 | Disorders of the orbit | Sense Organs | 1.08 | 0.961 – 1.2 | 0.207 | 352 | 3508 | all | phecode |
| 377 | Disorders of optic nerve and visual pathways | Sense Organs | 0.99 | 0.923 – 1.06 | 0.769 | 913 | 9021 | all | phecode |
| 377.1 | Optic atrophy | Sense Organs | 0.971 | 0.855 – 1.1 | 0.652 | 283 | 2793 | all | phecode |
| 377.3 | Optic neuritis/neuropathy | Sense Organs | 1 | 0.918 – 1.09 | 0.994 | 585 | 5775 | all | phecode |
| 378 |
Strabismus and other disorders of binocular eyeStrabismus and other disorders of binocular eye movements
|
Sense Organs | 0.972 | 0.917 – 1.03 | 0.345 | 1275 | 12460 | all | phecode |
| 378.1 | Strabismus (not specified as paralytic) | Sense Organs | 0.948 | 0.881 – 1.02 | 0.153 | 828 | 8130 | all | phecode |
| 378.2 | Nystagmus and other irregular eye movements | Sense Organs | 0.949 | 0.807 – 1.12 | 0.523 | 170 | 1686 | all | phecode |
| 378.5 | Paralytic strabismus | Sense Organs | 0.927 | 0.83 – 1.04 | 0.186 | 349 | 3437 | all | phecode |
| 379 | Other disorders of eye | Sense Organs | 0.932 | 0.903 – 0.962 | 1.14e-05 | 5046 | 29999 | all | phecode |
| 379.1 | Scleritis and episcleritis | Sense Organs | 0.844 | 0.725 – 0.983 | 0.0291 | 176 | 1743 | all | phecode |
| 379.2 | Disorders of vitreous body | Sense Organs | 0.91 | 0.877 – 0.944 | 5.1e-07 | 3634 | 23186 | all | phecode |
| 379.3 | Aphakia and other disorders of lens | Sense Organs | 0.941 | 0.786 – 1.13 | 0.511 | 135 | 1258 | all | phecode |
| 379.4 | Anomalies of pupillary function | Sense Organs | 0.938 | 0.828 – 1.06 | 0.32 | 287 | 2833 | all | phecode |
| 379.5 | Disorders of iris and ciliary body | Sense Organs | 1 | 0.89 – 1.13 | 0.958 | 304 | 2948 | all | phecode |
| 379.51 | Pigmentary iris degeneration | Sense Organs | 0.78 | 0.613 – 0.993 | 0.0439 | 77 | 731 | all | phecode |
| 379.9 | Pain, swelling or discharge of eye | Sense Organs | 0.944 | 0.887 – 1 | 0.0709 | 1129 | 11130 | all | phecode |
| 380 | Disorders of external ear | Sense Organs | 0.945 | 0.903 – 0.988 | 0.0135 | 2242 | 20393 | all | phecode |
| 380.1 | Otitis externa | Sense Organs | 1.03 | 0.972 – 1.09 | 0.339 | 1469 | 14580 | all | phecode |
| 380.4 | Impacted cerumen | Sense Organs | 0.943 | 0.905 – 0.983 | 0.00595 | 2648 | 23557 | all | phecode |
| 381 | Otitis media and Eustachian tube disorders | Sense Organs | 0.985 | 0.953 – 1.02 | 0.351 | 4255 | 36417 | all | phecode |
| 381.1 | Otitis media | Sense Organs | 1 | 0.963 – 1.04 | 0.983 | 3079 | 29813 | all | phecode |
| 381.11 | Suppurative and unspecified otitis media | Sense Organs | 1.01 | 0.967 – 1.05 | 0.733 | 2610 | 25602 | all | phecode |
| 381.2 | Eustachian tube disorders | Sense Organs | 0.95 | 0.904 – 0.998 | 0.0412 | 1816 | 17827 | all | phecode |
| 381.3 | Mastoiditis & related conditions | Sense Organs | 1.02 | 0.857 – 1.21 | 0.85 | 153 | 1530 | all | phecode |
| 381.9 | Otorrhea | Sense Organs | 1.04 | 0.929 – 1.15 | 0.526 | 372 | 3713 | all | phecode |
| 382 | Otalgia | Sense Organs | 1.02 | 0.974 – 1.07 | 0.365 | 1884 | 18673 | all | phecode |
| 383 | Otosclerosis | Sense Organs | 1.02 | 0.842 – 1.23 | 0.87 | 124 | 1240 | all | phecode |
| 384 | Other disorders of tympanic membrane | Sense Organs | 1.05 | 0.955 – 1.15 | 0.325 | 516 | 5156 | all | phecode |
| 384.1 | Myringitis | Sense Organs | 1.27 | 0.945 – 1.71 | 0.112 | 51 | 502 | all | phecode |
| 384.4 | Perforation of tympanic membrane | Sense Organs | 1.06 | 0.949 – 1.17 | 0.318 | 403 | 4029 | all | phecode |
| 385 | Other disorders of middle ear and mastoid | Sense Organs | 0.966 | 0.873 – 1.07 | 0.498 | 432 | 4320 | all | phecode |
| 385.3 | Cholesteatoma | Sense Organs | 0.949 | 0.836 – 1.08 | 0.422 | 277 | 2770 | all | phecode |
| 385.5 |
Tympanosclerosis and middle ear disease relatedTympanosclerosis and middle ear disease related to otitis media
|
Sense Organs | 0.922 | 0.764 – 1.11 | 0.396 | 118 | 1180 | all | phecode |
| 386 |
Vertiginous syndromes and other disorders ofVertiginous syndromes and other disorders of vestibular system
|
Sense Organs | 0.963 | 0.917 – 1.01 | 0.129 | 1882 | 18186 | all | phecode |
| 386.1 | Meniere's disease | Sense Organs | 0.957 | 0.85 – 1.08 | 0.465 | 319 | 3156 | all | phecode |
| 386.2 | Peripheral or central vertigo | Sense Organs | 0.961 | 0.911 – 1.01 | 0.139 | 1586 | 15423 | all | phecode |
| 386.21 | Central origin vertigo | Sense Organs | 0.98 | 0.922 – 1.04 | 0.508 | 1208 | 11844 | all | phecode |
| 386.3 | Labyrinthitis | Sense Organs | 0.971 | 0.919 – 1.03 | 0.301 | 1482 | 14530 | all | phecode |
| 386.9 |
Dizziness and giddiness (Light-headedness andDizziness and giddiness (Light-headedness and vertigo)
|
Sense Organs | 0.988 | 0.962 – 1.01 | 0.364 | 6933 | 38286 | all | phecode |
| 388 | Other disorders of ear | Sense Organs | 0.948 | 0.885 – 1.01 | 0.121 | 960 | 9501 | all | phecode |
| 389 | Hearing loss | Sense Organs | 0.972 | 0.948 – 0.997 | 0.0277 | 8182 | 38069 | all | phecode |
| 389.1 | Sensorineural hearing loss | Sense Organs | 0.937 | 0.906 – 0.969 | 0.000166 | 4107 | 29258 | all | phecode |
| 389.2 | Conductive hearing loss | Sense Organs | 1.01 | 0.941 – 1.08 | 0.795 | 905 | 9042 | all | phecode |
| 389.3 | Degenerative and vascular disorders of ear | Sense Organs | 1.03 | 0.883 – 1.19 | 0.741 | 192 | 1808 | all | phecode |
| 389.4 | Tinnitus | Sense Organs | 0.93 | 0.89 – 0.973 | 0.0014 | 2291 | 22130 | all | phecode |
| 389.5 | Disorders of acoustic nerve | Sense Organs | 0.946 | 0.783 – 1.14 | 0.569 | 124 | 1229 | all | phecode |
| 394 | Rheumatic disease of the heart valves | Circulatory System | 0.977 | 0.924 – 1.03 | 0.421 | 1458 | 13732 | all | phecode |
| 394.1 | Mitral valve stenosis and aortic valve stenosis | Circulatory System | 0.888 | 0.792 – 0.996 | 0.042 | 350 | 3415 | all | phecode |
| 394.2 | Mitral valve disease | Circulatory System | 0.964 | 0.873 – 1.06 | 0.468 | 462 | 4560 | all | phecode |
| 394.3 | Aortic valve disease | Circulatory System | 0.897 | 0.763 – 1.05 | 0.189 | 176 | 1691 | all | phecode |
| 394.4 | Acute rheumatic heart disease | Circulatory System | 0.927 | 0.705 – 1.22 | 0.586 | 55 | 546 | all | phecode |
| 394.7 | Disease of tricuspid valve | Circulatory System | 1.04 | 0.953 – 1.14 | 0.378 | 587 | 5739 | all | phecode |
| 395 | Heart valve disorders | Circulatory System | 1.03 | 0.996 – 1.07 | 0.0808 | 3976 | 28748 | all | phecode |
| 395.1 | Nonrheumatic mitral valve disorders | Circulatory System | 1.03 | 0.987 – 1.08 | 0.164 | 2175 | 20441 | all | phecode |
| 395.2 | Nonrheumatic aortic valve disorders | Circulatory System | 1.04 | 0.989 – 1.09 | 0.132 | 2060 | 17194 | all | phecode |
| 395.3 | Nonrheumatic tricuspid valve disorders | Circulatory System | 1.03 | 0.942 – 1.14 | 0.478 | 493 | 4864 | all | phecode |
| 395.4 | Nonrheumatic pulmonary valve disorders | Circulatory System | 0.945 | 0.774 – 1.15 | 0.578 | 108 | 1080 | all | phecode |
| 395.6 | Heart valve replaced | Circulatory System | 1.03 | 0.969 – 1.1 | 0.338 | 1177 | 10833 | all | phecode |
| 396 | Abnormal heart sounds | Circulatory System | 1.01 | 0.977 – 1.04 | 0.608 | 4718 | 34395 | all | phecode |
| 401 | Hypertension | Circulatory System | 1.07 | 1.04 – 1.09 | 3.53e-09 | 23317 | 23367 | all | phecode |
| 401.1 | Essential hypertension | Circulatory System | 1.07 | 1.04 – 1.09 | 4.51e-09 | 23158 | 23364 | all | phecode |
| 401.2 | Hypertensive heart and/or renal disease | Circulatory System | 1.1 | 1.05 – 1.14 | 5.95e-06 | 3503 | 14616 | all | phecode |
| 401.21 | Hypertensive heart disease | Circulatory System | 1.1 | 1.02 – 1.18 | 0.012 | 893 | 6607 | all | phecode |
| 401.22 | Hypertensive chronic kidney disease | Circulatory System | 1.1 | 1.05 – 1.15 | 2.76e-05 | 2584 | 13072 | all | phecode |
| 401.3 | Other hypertensive complications | Circulatory System | 1.08 | 1.03 – 1.12 | 0.00101 | 2679 | 15833 | all | phecode |
| 411 | Ischemic Heart Disease | Circulatory System | 1.07 | 1.04 – 1.1 | 1.95e-07 | 8807 | 30299 | all | phecode |
| 411.1 | Unstable angina (intermediate coronary syndrome) | Circulatory System | 1.08 | 1.01 – 1.16 | 0.0255 | 937 | 8574 | all | phecode |
| 411.2 | Myocardial infarction | Circulatory System | 1.09 | 1.05 – 1.13 | 8.92e-06 | 3594 | 21716 | all | phecode |
| 411.3 | Angina pectoris | Circulatory System | 1.09 | 1.05 – 1.14 | 4.89e-05 | 2485 | 18304 | all | phecode |
| 411.4 | Coronary atherosclerosis | Circulatory System | 1.07 | 1.04 – 1.1 | 1.2e-06 | 7555 | 27492 | all | phecode |
| 411.41 | Aneurysm and dissection of heart | Circulatory System | 1.09 | 0.916 – 1.29 | 0.344 | 156 | 1529 | all | phecode |
| 411.8 |
Other chronic ischemic heart diseaseOther chronic ischemic heart disease, unspecified
|
Circulatory System | 1.08 | 1.04 – 1.11 | 1.77e-06 | 6331 | 25741 | all | phecode |
| 411.9 |
Other acute and subacute forms of ischemicOther acute and subacute forms of ischemic heart disease
|
Circulatory System | 1.07 | 0.968 – 1.18 | 0.185 | 442 | 4211 | all | phecode |
| 414 | Other forms of chronic heart disease | Circulatory System | 1.04 | 1 – 1.08 | 0.043 | 3101 | 22616 | all | phecode |
| 414.2 | ASCVD | Circulatory System | 1 | 0.928 – 1.09 | 0.912 | 718 | 6816 | all | phecode |
| 415 | Pulmonary heart disease | Circulatory System | 1.05 | 1.01 – 1.09 | 0.0139 | 3366 | 30208 | all | phecode |
| 415.1 | Acute pulmonary heart disease | Circulatory System | 1.03 | 0.983 – 1.08 | 0.204 | 1912 | 19014 | all | phecode |
| 415.11 | Pulmonary embolism and infarction, acute | Circulatory System | 1.03 | 0.984 – 1.08 | 0.193 | 1906 | 18953 | all | phecode |
| 415.2 | Chronic pulmonary heart disease | Circulatory System | 1.08 | 1.03 – 1.14 | 0.00214 | 1808 | 17605 | all | phecode |
| 415.21 | Primary pulmonary hypertension | Circulatory System | 1.14 | 1.06 – 1.24 | 0.000986 | 706 | 7032 | all | phecode |
| 416 | Cardiomegaly | Circulatory System | 1.01 | 0.954 – 1.08 | 0.673 | 1254 | 12372 | all | phecode |
| 418 | Nonspecific chest pain | Circulatory System | 1.02 | 1 – 1.05 | 0.0333 | 12650 | 33952 | all | phecode |
| 418.1 | Precordial pain | Circulatory System | 1.01 | 0.959 – 1.07 | 0.625 | 1471 | 13782 | all | phecode |
| 420 | Carditis | Circulatory System | 1.03 | 0.977 – 1.09 | 0.275 | 1588 | 15680 | all | phecode |
| 420.1 | Myocarditis | Circulatory System | 1.12 | 0.901 – 1.39 | 0.312 | 97 | 958 | all | phecode |
| 420.2 | Pericarditis | Circulatory System | 1.01 | 0.941 – 1.09 | 0.752 | 842 | 8402 | all | phecode |
| 420.21 | Acute pericarditis | Circulatory System | 1.02 | 0.876 – 1.19 | 0.799 | 177 | 1764 | all | phecode |
| 420.22 | Chronic pericarditis | Circulatory System | 0.987 | 0.812 – 1.2 | 0.891 | 117 | 1153 | all | phecode |
| 420.3 | Endocarditis | Circulatory System | 1.04 | 0.968 – 1.13 | 0.268 | 764 | 7535 | all | phecode |
| 425 | Cardiomyopathy | Circulatory System | 1.05 | 1 – 1.1 | 0.05 | 2078 | 19881 | all | phecode |
| 425.1 | Primary/intrinsic cardiomyopathies | Circulatory System | 1.04 | 0.996 – 1.09 | 0.0756 | 1989 | 19025 | all | phecode |
| 425.11 | Hypertrophic obstructive cardiomyopathy | Circulatory System | 1.01 | 0.879 – 1.17 | 0.844 | 208 | 2050 | all | phecode |
| 425.12 | Other hypertrophic cardiomyopathy | Circulatory System | 1.03 | 0.887 – 1.19 | 0.713 | 201 | 1992 | all | phecode |
| 425.2 | Secondary/extrinsic cardiomyopathies | Circulatory System | 0.987 | 0.878 – 1.11 | 0.827 | 317 | 3170 | all | phecode |
| 425.8 | Other cardiomyopathy | Circulatory System | 1.09 | 0.879 – 1.34 | 0.445 | 95 | 931 | all | phecode |
| 426 | Cardiac conduction disorders | Circulatory System | 1.03 | 1.01 – 1.05 | 0.0172 | 12327 | 25440 | all | phecode |
| 426.2 | Atrioventricular [AV] block | Circulatory System | 1.04 | 0.985 – 1.09 | 0.166 | 1903 | 11501 | all | phecode |
| 426.21 | First degree AV block | Circulatory System | 1.05 | 0.987 – 1.11 | 0.125 | 1313 | 8899 | all | phecode |
| 426.22 | Mobitz II AV block | Circulatory System | 1 | 0.759 – 1.32 | 0.991 | 64 | 553 | all | phecode |
| 426.23 | Second degree AV block | Circulatory System | 0.996 | 0.865 – 1.15 | 0.952 | 216 | 1925 | all | phecode |
| 426.24 | Atrioventricular block, complete | Circulatory System | 0.993 | 0.9 – 1.1 | 0.89 | 461 | 3823 | all | phecode |
| 426.25 | Other heart block | Circulatory System | 1.12 | 0.967 – 1.29 | 0.134 | 203 | 1803 | all | phecode |
| 426.3 | Bundle branch block | Circulatory System | 0.978 | 0.934 – 1.02 | 0.348 | 2306 | 13999 | all | phecode |
| 426.31 | Right bundle branch block | Circulatory System | 0.979 | 0.925 – 1.04 | 0.467 | 1423 | 10758 | all | phecode |
| 426.32 | Left bundle branch block | Circulatory System | 0.978 | 0.914 – 1.05 | 0.527 | 969 | 8110 | all | phecode |
| 426.4 | Anomalous atrioventricular excitation | Circulatory System | 0.928 | 0.737 – 1.17 | 0.523 | 82 | 820 | all | phecode |
| 426.7 | Abnormal electrocardiogram [ECG] [EKG] | Circulatory System | 1.03 | 1.01 – 1.06 | 0.00828 | 10577 | 25186 | all | phecode |
| 426.8 | Other cardiac conduction disorders | Circulatory System | 1.07 | 0.984 – 1.16 | 0.118 | 679 | 6650 | all | phecode |
| 426.9 | Cardiac pacemaker/device in situ | Circulatory System | 1.02 | 0.972 – 1.08 | 0.374 | 1754 | 11536 | all | phecode |
| 426.91 | Cardiac pacemaker in situ | Circulatory System | 1.01 | 0.946 – 1.07 | 0.823 | 1171 | 8184 | all | phecode |
| 426.92 | Cardiac defibrillator in situ | Circulatory System | 1.01 | 0.943 – 1.09 | 0.708 | 846 | 7320 | all | phecode |
| 427 | Cardiac dysrhythmias | Circulatory System | 1.02 | 1 – 1.05 | 0.0216 | 17397 | 25735 | all | phecode |
| 427.1 | Paroxysmal tachycardia, unspecified | Circulatory System | 1.01 | 0.963 – 1.05 | 0.813 | 2474 | 18178 | all | phecode |
| 427.11 | Paroxysmal supraventricular tachycardia | Circulatory System | 1 | 0.949 – 1.05 | 0.991 | 1595 | 14293 | all | phecode |
| 427.12 | Paroxysmal ventricular tachycardia | Circulatory System | 1.01 | 0.95 – 1.08 | 0.734 | 1181 | 9915 | all | phecode |
| 427.2 | Atrial fibrillation and flutter | Circulatory System | 1.03 | 0.991 – 1.06 | 0.147 | 5313 | 18688 | all | phecode |
| 427.21 | Atrial fibrillation | Circulatory System | 1.02 | 0.988 – 1.06 | 0.205 | 5188 | 18409 | all | phecode |
| 427.22 | Atrial flutter | Circulatory System | 0.998 | 0.946 – 1.05 | 0.933 | 1693 | 11042 | all | phecode |
| 427.3 | Other specified cardiac dysrhythmias | Circulatory System | 1.02 | 0.998 – 1.05 | 0.0752 | 8688 | 25552 | all | phecode |
| 427.4 | Cardiac arrest and ventricular fibrillation | Circulatory System | 1.09 | 0.992 – 1.19 | 0.0747 | 536 | 5233 | all | phecode |
| 427.41 | Ventricular fibrillation and flutter | Circulatory System | 0.981 | 0.852 – 1.13 | 0.787 | 216 | 2118 | all | phecode |
| 427.42 | Cardiac arrest | Circulatory System | 1.14 | 1.03 – 1.27 | 0.0133 | 410 | 4034 | all | phecode |
| 427.5 | Arrhythmia (cardiac) NOS | Circulatory System | 1.01 | 0.985 – 1.04 | 0.35 | 6905 | 25457 | all | phecode |
| 427.6 | Premature beats | Circulatory System | 0.986 | 0.943 – 1.03 | 0.542 | 2359 | 16248 | all | phecode |
| 427.61 | Supraventricular premature beats | Circulatory System | 0.969 | 0.893 – 1.05 | 0.442 | 670 | 6287 | all | phecode |
| 427.7 | Tachycardia NOS | Circulatory System | 1.04 | 1.01 – 1.08 | 0.00735 | 5124 | 25531 | all | phecode |
| 427.8 | Sinoatrial node dysfunction (Bradycardia) | Circulatory System | 1.01 | 0.94 – 1.08 | 0.808 | 912 | 7501 | all | phecode |
| 427.9 | Palpitations | Circulatory System | 0.979 | 0.947 – 1.01 | 0.218 | 4430 | 24505 | all | phecode |
| 428 | Congestive heart failure; nonhypertensive | Circulatory System | 1.07 | 1.03 – 1.1 | 0.00018 | 4300 | 23663 | all | phecode |
| 428.1 | Congestive heart failure (CHF) NOS | Circulatory System | 1.06 | 1.02 – 1.1 | 0.0018 | 3756 | 22446 | all | phecode |
| 428.2 | Heart failure NOS | Circulatory System | 1.07 | 1.03 – 1.11 | 0.000167 | 3701 | 21722 | all | phecode |
| 428.3 |
Heart failure with reduced EF [Systolic orHeart failure with reduced EF [Systolic or combined heart failure]
|
Circulatory System | 1.1 | 1.05 – 1.16 | 0.000211 | 1765 | 14476 | all | phecode |
| 428.4 |
Heart failure with preserved EF [DiastolicHeart failure with preserved EF [Diastolic heart failure]
|
Circulatory System | 1.07 | 1.02 – 1.13 | 0.00942 | 1648 | 13395 | all | phecode |
| 429 |
Ill-defined descriptions and complications ofIll-defined descriptions and complications of heart disease
|
Circulatory System | 1.02 | 0.998 – 1.04 | 0.0726 | 12635 | 32504 | all | phecode |
| 429.1 | Heart transplant/surgery | Circulatory System | 1.07 | 1.01 – 1.14 | 0.0312 | 1219 | 11696 | all | phecode |
| 429.2 | Abnormal function study of cardiovascular system | Circulatory System | 1.04 | 1.01 – 1.07 | 0.0164 | 6322 | 29232 | all | phecode |
| 429.3 | Symptoms involving cardiovascular system | Circulatory System | 1.01 | 0.989 – 1.04 | 0.304 | 9650 | 32421 | all | phecode |
| 429.9 | Cardiac complications, not elsewhere classified | Circulatory System | 0.993 | 0.917 – 1.07 | 0.856 | 723 | 7072 | all | phecode |
| 430 | Intracranial hemorrhage | Circulatory System | 1.05 | 0.969 – 1.13 | 0.25 | 789 | 7842 | all | phecode |
| 430.1 | Subarachnoid hemorrhage | Circulatory System | 1.22 | 1.06 – 1.39 | 0.00433 | 261 | 2610 | all | phecode |
| 430.2 | Intracerebral hemorrhage | Circulatory System | 1.08 | 0.964 – 1.2 | 0.192 | 368 | 3671 | all | phecode |
| 430.3 | Subdural hemorrhage | Circulatory System | 0.993 | 0.87 – 1.13 | 0.923 | 272 | 2680 | all | phecode |
| 433 | Cerebrovascular disease | Circulatory System | 1.06 | 1.03 – 1.09 | 0.000182 | 5463 | 32242 | all | phecode |
| 433.1 | Occlusion and stenosis of precerebral arteries | Circulatory System | 1.08 | 1.03 – 1.13 | 0.00248 | 1978 | 16212 | all | phecode |
| 433.11 |
Occlusion of cerebral arteries, with cerebralOcclusion of cerebral arteries, with cerebral infarction
|
Circulatory System | 1.06 | 0.933 – 1.21 | 0.352 | 260 | 2517 | all | phecode |
| 433.12 | Cerebral atherosclerosis | Circulatory System | 1.05 | 0.832 – 1.32 | 0.695 | 80 | 789 | all | phecode |
| 433.2 | Occlusion of cerebral arteries | Circulatory System | 1.05 | 1 – 1.09 | 0.043 | 2437 | 21732 | all | phecode |
| 433.21 |
Cerebral artery occlusion, with cerebralCerebral artery occlusion, with cerebral infarction
|
Circulatory System | 1.05 | 1 – 1.1 | 0.0317 | 2357 | 21103 | all | phecode |
| 433.3 | Cerebral ischemia | Circulatory System | 1.03 | 0.992 – 1.08 | 0.11 | 2780 | 22868 | all | phecode |
| 433.31 | Transient cerebral ischemia | Circulatory System | 1.04 | 0.996 – 1.09 | 0.0775 | 2409 | 20762 | all | phecode |
| 433.5 | Cerebral aneurysm | Circulatory System | 1.17 | 1.06 – 1.29 | 0.00251 | 474 | 4724 | all | phecode |
| 433.6 | Acute, but ill-defined cerebrovascular disease | Circulatory System | 1.01 | 0.913 – 1.11 | 0.904 | 464 | 4518 | all | phecode |
| 433.8 | Late effects of cerebrovascular disease | Circulatory System | 1.05 | 0.97 – 1.14 | 0.222 | 695 | 6822 | all | phecode |
| 440 | Atherosclerosis | Circulatory System | 1.13 | 1.08 – 1.18 | 1.74e-08 | 2477 | 19724 | all | phecode |
| 440.1 | Atherosclerosis of renal artery | Circulatory System | 1.09 | 0.943 – 1.26 | 0.244 | 231 | 2291 | all | phecode |
| 440.2 | Atherosclerosis of the extremities | Circulatory System | 1.14 | 1.08 – 1.21 | 1.6e-06 | 1516 | 13532 | all | phecode |
| 440.21 |
Atherosclerosis of native arteries of theAtherosclerosis of native arteries of the extremities with ulceration or gangrene
|
Circulatory System | 1.23 | 1.08 – 1.4 | 0.00156 | 274 | 2669 | all | phecode |
| 440.22 |
Atherosclerosis of native arteries of theAtherosclerosis of native arteries of the extremities with intermittent claudication
|
Circulatory System | 1.16 | 1.09 – 1.24 | 7.66e-06 | 1040 | 9647 | all | phecode |
| 440.9 | Atherosclerosis of aorta | Circulatory System | 1.16 | 1.08 – 1.25 | 5.34e-05 | 846 | 8124 | all | phecode |
| 441 | Vascular insufficiency of intestine | Circulatory System | 1.17 | 1.06 – 1.28 | 0.00119 | 515 | 5115 | all | phecode |
| 441.1 | Acute vascular insufficiency of intestine | Circulatory System | 1.05 | 0.913 – 1.2 | 0.52 | 240 | 2387 | all | phecode |
| 441.2 | Chronic vascular insufficiency of intestine | Circulatory System | 1.24 | 1.05 – 1.47 | 0.0134 | 154 | 1536 | all | phecode |
| 442 | Other aneurysm | Circulatory System | 1.07 | 1.03 – 1.12 | 0.000927 | 2779 | 21466 | all | phecode |
| 442.1 | Aortic aneurysm | Circulatory System | 1.09 | 1.04 – 1.14 | 0.000643 | 2054 | 16492 | all | phecode |
| 442.11 | Abdominal aortic aneurysm | Circulatory System | 1.13 | 1.06 – 1.2 | 8.6e-05 | 1189 | 10558 | all | phecode |
| 442.2 | Aneurysm of iliac artery | Circulatory System | 1.15 | 0.989 – 1.33 | 0.0697 | 202 | 2002 | all | phecode |
| 442.3 | Aneurysm of artery of lower extremity | Circulatory System | 1.06 | 0.911 – 1.24 | 0.436 | 179 | 1765 | all | phecode |
| 442.4 | Arterial dissection | Circulatory System | 1.02 | 0.876 – 1.19 | 0.776 | 184 | 1840 | all | phecode |
| 442.8 | Aneurysm of other specified artery | Circulatory System | 0.957 | 0.862 – 1.06 | 0.419 | 399 | 3978 | all | phecode |
| 443 | Peripheral vascular disease | Circulatory System | 1.05 | 1.01 – 1.09 | 0.0102 | 3086 | 24814 | all | phecode |
| 443.1 | Raynaud's syndrome | Circulatory System | 0.951 | 0.879 – 1.03 | 0.203 | 742 | 7390 | all | phecode |
| 443.7 |
Peripheral angiopathy in diseases classifiedPeripheral angiopathy in diseases classified elsewhere
|
Circulatory System | 1.05 | 0.91 – 1.21 | 0.498 | 220 | 2087 | all | phecode |
| 443.8 | Other specified peripheral vascular diseases | Circulatory System | 1.06 | 1.02 – 1.11 | 0.00431 | 2557 | 21985 | all | phecode |
| 443.9 | Peripheral vascular disease, unspecified | Circulatory System | 1.1 | 1.06 – 1.15 | 1.2e-05 | 2341 | 18862 | all | phecode |
| 444 | Arterial embolism and thrombosis | Circulatory System | 1.16 | 1.08 – 1.24 | 8.16e-05 | 848 | 8423 | all | phecode |
| 444.1 |
Arterial embolism and thrombosis of lowerArterial embolism and thrombosis of lower extremity artery
|
Circulatory System | 1.21 | 1.07 – 1.36 | 0.00226 | 313 | 3099 | all | phecode |
| 444.2 | Embolism and thrombosis of abdominal aorta | Circulatory System | 1.31 | 1.11 – 1.56 | 0.00167 | 155 | 1548 | all | phecode |
| 446 | Polyarteritis nodosa and allied conditions | Circulatory System | 1.05 | 0.95 – 1.15 | 0.36 | 460 | 4559 | all | phecode |
| 446.4 | Wegener's granulomatosis | Circulatory System | 1.04 | 0.862 – 1.26 | 0.662 | 109 | 1075 | all | phecode |
| 446.5 | Giant cell arteritis | Circulatory System | 1.14 | 0.908 – 1.42 | 0.261 | 79 | 749 | all | phecode |
| 446.9 | Arteritis NOS | Circulatory System | 1.04 | 0.918 – 1.17 | 0.552 | 289 | 2876 | all | phecode |
| 447 | Other disorders of arteries and arterioles | Circulatory System | 1.03 | 0.985 – 1.07 | 0.21 | 2647 | 22765 | all | phecode |
| 447.1 | Stricture of artery | Circulatory System | 1.22 | 1.11 – 1.33 | 3.95e-05 | 523 | 5163 | all | phecode |
| 447.7 | Aortic ectasia | Circulatory System | 0.961 | 0.892 – 1.04 | 0.294 | 804 | 7938 | all | phecode |
| 448 | Disease of capillaries | Circulatory System | 0.909 | 0.857 – 0.965 | 0.00182 | 1237 | 12127 | all | phecode |
| 450 | Noninfectious disorders of lymphatic channels | Circulatory System | 1 | 0.957 – 1.05 | 0.926 | 2104 | 20985 | all | phecode |
| 451 | Phlebitis and thrombophlebitis | Circulatory System | 0.963 | 0.892 – 1.04 | 0.343 | 738 | 7355 | all | phecode |
| 451.2 |
Phlebitis and thrombophlebitis of lowerPhlebitis and thrombophlebitis of lower extremities
|
Circulatory System | 0.905 | 0.79 – 1.04 | 0.151 | 244 | 2437 | all | phecode |
| 452 | Other venous embolism and thrombosis | Circulatory System | 1.03 | 0.999 – 1.06 | 0.0614 | 4957 | 29867 | all | phecode |
| 452.1 | Iatrogenic pulmonary embolism and infarction | Circulatory System | 0.899 | 0.791 – 1.02 | 0.101 | 276 | 2747 | all | phecode |
| 452.2 | Deep vein thrombosis [DVT] | Circulatory System | 1.02 | 0.986 – 1.06 | 0.228 | 3260 | 26940 | all | phecode |
| 452.8 | Postphlebitic syndrome | Circulatory System | 0.897 | 0.76 – 1.06 | 0.204 | 154 | 1529 | all | phecode |
| 453 | Chronic venous hypertension | Circulatory System | 0.975 | 0.845 – 1.12 | 0.73 | 220 | 2168 | all | phecode |
| 454 | Varicose veins | Circulatory System | 0.969 | 0.931 – 1.01 | 0.126 | 2827 | 24555 | all | phecode |
| 454.1 | Varicose veins of lower extremity | Circulatory System | 0.968 | 0.927 – 1.01 | 0.139 | 2469 | 21426 | all | phecode |
| 454.11 | Varicose veins of lower extremity, symptomtic | Circulatory System | 0.956 | 0.906 – 1.01 | 0.102 | 1565 | 15056 | all | phecode |
| 455 | Hemorrhoids | Circulatory System | 0.954 | 0.927 – 0.983 | 0.00188 | 5799 | 29818 | all | phecode |
| 456 | Chronic venous insufficiency [CVI] | Circulatory System | 0.992 | 0.955 – 1.03 | 0.695 | 3097 | 24898 | all | phecode |
| 457 |
Encounter for long-term (current) use ofEncounter for long-term (current) use of anticoagulants, antithrombotics, aspirin
|
Circulatory System | 1.01 | 0.964 – 1.06 | 0.678 | 2095 | 15309 | all | phecode |
| 457.2 |
Encounter for long-term (current) use ofEncounter for long-term (current) use of antiplatelets/antithrombotics
|
Circulatory System | 1.04 | 0.929 – 1.17 | 0.474 | 324 | 3221 | all | phecode |
| 457.3 | Encounter for long-term (current) use of aspirin | Circulatory System | 1.02 | 0.974 – 1.07 | 0.381 | 1973 | 14689 | all | phecode |
| 458 | Hypotension | Circulatory System | 1.04 | 1.01 – 1.07 | 0.017 | 5091 | 32185 | all | phecode |
| 458.1 | Orthostatic hypotension | Circulatory System | 1.01 | 0.957 – 1.07 | 0.638 | 1344 | 12938 | all | phecode |
| 458.2 | Iatrogenic hypotension | Circulatory System | 1.09 | 1.02 – 1.16 | 0.00727 | 1109 | 11012 | all | phecode |
| 458.9 | Hypotension NOS | Circulatory System | 1.04 | 1.01 – 1.08 | 0.00731 | 4618 | 31186 | all | phecode |
| 459 | Other disorders of circulatory system | Circulatory System | 1.03 | 1 – 1.05 | 0.0473 | 7825 | 34792 | all | phecode |
| 459.1 | Hemorrhage NOS | Circulatory System | 1.01 | 0.937 – 1.08 | 0.828 | 834 | 8215 | all | phecode |
| 459.7 | Blood vessel replaced | Circulatory System | 1.07 | 1.01 – 1.13 | 0.0243 | 1305 | 13023 | all | phecode |
| 459.9 | Circulatory disease NEC | Circulatory System | 1.03 | 1 – 1.06 | 0.0458 | 6706 | 33592 | all | phecode |
| 464 | Acute sinusitis | Respiratory | 0.975 | 0.945 – 1.01 | 0.11 | 4792 | 32137 | all | phecode |
| 465 |
Acute upper respiratory infections of multipleAcute upper respiratory infections of multiple or unspecified sites
|
Respiratory | 0.968 | 0.946 – 0.991 | 0.0075 | 9601 | 35915 | all | phecode |
| 465.2 | Acute pharyngitis | Respiratory | 0.95 | 0.922 – 0.979 | 0.000923 | 5310 | 32365 | all | phecode |
| 465.4 | Acute laryngitis and tracheitis | Respiratory | 0.981 | 0.887 – 1.08 | 0.707 | 443 | 4428 | all | phecode |
| 470 | Septal Deviations/Turbinate Hypertrophy | Respiratory | 0.977 | 0.929 – 1.03 | 0.357 | 1797 | 17640 | all | phecode |
| 471 | Nasal polyps | Respiratory | 0.989 | 0.907 – 1.08 | 0.808 | 592 | 5881 | all | phecode |
| 472 | Chronic pharyngitis and nasopharyngitis | Respiratory | 0.962 | 0.915 – 1.01 | 0.136 | 1797 | 16986 | all | phecode |
| 473 | Diseases of the larynx and vocal cords | Respiratory | 0.996 | 0.958 – 1.04 | 0.858 | 2983 | 25244 | all | phecode |
| 473.1 | Chronic laryngitis | Respiratory | 0.983 | 0.761 – 1.27 | 0.899 | 68 | 674 | all | phecode |
| 473.3 | Paralysis/spasm of vocal cords or larynx | Respiratory | 0.983 | 0.903 – 1.07 | 0.69 | 628 | 6254 | all | phecode |
| 473.4 | Voice disturbance | Respiratory | 0.993 | 0.95 – 1.04 | 0.744 | 2336 | 21975 | all | phecode |
| 474 | Acute and chronic tonsillitis | Respiratory | 1.01 | 0.942 – 1.09 | 0.759 | 880 | 7892 | all | phecode |
| 474.1 | Acute tonsillitis | Respiratory | 0.995 | 0.887 – 1.12 | 0.926 | 335 | 3181 | all | phecode |
| 474.2 | Chronic tonsillitis and adenoiditis | Respiratory | 1.03 | 0.95 – 1.11 | 0.48 | 700 | 6445 | all | phecode |
| 475 | Chronic sinusitis | Respiratory | 0.984 | 0.952 – 1.02 | 0.332 | 4378 | 27891 | all | phecode |
| 475.9 | Postnasal drip | Respiratory | 0.911 | 0.849 – 0.977 | 0.00884 | 922 | 9017 | all | phecode |
| 476 | Allergic rhinitis | Respiratory | 0.97 | 0.949 – 0.991 | 0.00544 | 12687 | 28117 | all | phecode |
| 477 | Epistaxis or throat hemorrhage | Respiratory | 0.995 | 0.935 – 1.06 | 0.866 | 1150 | 11318 | all | phecode |
| 478 | Throat pain | Respiratory | 0.988 | 0.891 – 1.1 | 0.815 | 426 | 4195 | all | phecode |
| 479 | Other upper respiratory disease | Respiratory | 1 | 0.974 – 1.03 | 0.815 | 5627 | 28048 | all | phecode |
| 480 | Pneumonia | Respiratory | 1.03 | 1 – 1.06 | 0.0458 | 5947 | 37034 | all | phecode |
| 480.1 | Bacterial pneumonia | Respiratory | 1.05 | 0.985 – 1.11 | 0.142 | 1155 | 11495 | all | phecode |
| 480.11 | Pneumococcal pneumonia | Respiratory | 1.03 | 0.944 – 1.12 | 0.505 | 568 | 5644 | all | phecode |
| 480.12 | Pseudomonal pneumonia | Respiratory | 1.03 | 0.871 – 1.22 | 0.734 | 153 | 1523 | all | phecode |
| 480.13 | MRSA pneumonia | Respiratory | 1.2 | 0.988 – 1.45 | 0.0659 | 117 | 1165 | all | phecode |
| 480.2 | Viral pneumonia | Respiratory | 1.14 | 0.985 – 1.32 | 0.079 | 202 | 1992 | all | phecode |
| 480.3 | Pneumonia due to fungus (mycoses) | Respiratory | 1.15 | 0.978 – 1.36 | 0.0902 | 159 | 1590 | all | phecode |
| 480.5 | Bronchopneumonia and lung abscess | Respiratory | 1 | 0.839 – 1.2 | 0.979 | 135 | 1312 | all | phecode |
| 481 | Influenza | Respiratory | 0.996 | 0.94 – 1.05 | 0.878 | 1355 | 13284 | all | phecode |
| 483 | Acute bronchitis and bronchiolitis | Respiratory | 0.956 | 0.922 – 0.992 | 0.0167 | 3412 | 29871 | all | phecode |
| 495 | Asthma | Respiratory | 1.04 | 1.01 – 1.06 | 0.00472 | 8671 | 33569 | all | phecode |
| 495.1 | Chronic obstructive asthma | Respiratory | 1.12 | 1.01 – 1.25 | 0.0308 | 397 | 3925 | all | phecode |
| 495.11 | Chronic obstructive asthma with exacerbation | Respiratory | 0.992 | 0.782 – 1.26 | 0.947 | 81 | 802 | all | phecode |
| 495.2 | Asthma with exacerbation | Respiratory | 0.952 | 0.904 – 1 | 0.0664 | 1629 | 16033 | all | phecode |
| 496 | Chronic airway obstruction | Respiratory | 1.23 | 1.19 – 1.27 | 1.66e-39 | 5343 | 28343 | all | phecode |
| 496.1 | Emphysema | Respiratory | 1.3 | 1.24 – 1.37 | 1.03e-28 | 2134 | 19414 | all | phecode |
| 496.2 | Chronic bronchitis | Respiratory | 1.25 | 1.21 – 1.3 | 1.07e-37 | 4128 | 26624 | all | phecode |
| 496.21 | Obstructive chronic bronchitis | Respiratory | 1.27 | 1.22 – 1.31 | 5.08e-38 | 3747 | 25467 | all | phecode |
| 496.3 | Bronchiectasis | Respiratory | 1.01 | 0.924 – 1.1 | 0.826 | 549 | 5453 | all | phecode |
| 497 | Bronchitis | Respiratory | 1.01 | 0.963 – 1.06 | 0.67 | 1946 | 18824 | all | phecode |
| 498 | Acute bronchospasm | Respiratory | 0.997 | 0.907 – 1.1 | 0.946 | 496 | 4943 | all | phecode |
| 499 | Cystic fibrosis | Respiratory | 1 | 0.844 – 1.18 | 0.997 | 151 | 1510 | all | phecode |
| 500 | Lung disease due to external agents | Respiratory | 1.07 | 0.976 – 1.17 | 0.153 | 557 | 5551 | all | phecode |
| 500.1 | Extrinsic allergic alveolitis | Respiratory | 1.13 | 0.907 – 1.4 | 0.284 | 92 | 920 | all | phecode |
| 500.2 | Pneumoconiosis | Respiratory | 1.3 | 1.03 – 1.63 | 0.0255 | 78 | 764 | all | phecode |
| 501 | Pneumonitis due to inhalation of food or vomitus | Respiratory | 1.13 | 1.04 – 1.23 | 0.00346 | 634 | 6225 | all | phecode |
| 502 | Postinflammatory pulmonary fibrosis | Respiratory | 1.09 | 1.01 – 1.17 | 0.0258 | 815 | 8076 | all | phecode |
| 503 | Pulmonary congestion and hypostasis | Respiratory | 1.1 | 1.03 – 1.19 | 0.00799 | 835 | 8243 | all | phecode |
| 504 | Other alveolar and parietoalveolar pneumonopathy | Respiratory | 1.08 | 0.988 – 1.17 | 0.0919 | 595 | 5878 | all | phecode |
| 504.1 | Idiopathic fibrosing alveolitis | Respiratory | 0.992 | 0.882 – 1.12 | 0.894 | 311 | 3084 | all | phecode |
| 505 | Other pulmonary inflamation or edema | Respiratory | 1.08 | 1.03 – 1.14 | 0.00339 | 1638 | 15749 | all | phecode |
| 506 | Empyema and pneumothorax | Respiratory | 1.08 | 1.04 – 1.12 | 0.000129 | 2894 | 25235 | all | phecode |
| 507 | Pleurisy; pleural effusion | Respiratory | 1.05 | 1.01 – 1.09 | 0.0157 | 2916 | 26208 | all | phecode |
| 508 |
Pulmonary collapse; interstitial andPulmonary collapse; interstitial and compensatory emphysema
|
Respiratory | 1.05 | 1 – 1.09 | 0.0401 | 2382 | 22588 | all | phecode |
| 509 | Respiratory failure, insufficiency, arrest | Respiratory | 1.1 | 1.07 – 1.14 | 1.61e-08 | 4032 | 29477 | all | phecode |
| 509.1 | Respiratory failure | Respiratory | 1.12 | 1.07 – 1.17 | 4.11e-06 | 1937 | 18949 | all | phecode |
| 509.2 | Respiratory insufficiency | Respiratory | 1.1 | 1.03 – 1.17 | 0.0024 | 1174 | 11679 | all | phecode |
| 509.3 |
Pulmonary insufficiency or respiratory failurePulmonary insufficiency or respiratory failure following trauma and surgery
|
Respiratory | 1.11 | 1.05 – 1.17 | 0.000107 | 1689 | 16489 | all | phecode |
| 509.8 |
Dependence on respirator [Ventilator] orDependence on respirator [Ventilator] or supplemental oxygen
|
Respiratory | 1.12 | 1.07 – 1.18 | 8.63e-06 | 1741 | 17249 | all | phecode |
| 510 | Other diseases of lung | Respiratory | 1.03 | 0.998 – 1.06 | 0.0712 | 5503 | 35907 | all | phecode |
| 510.2 | Lung transplant | Respiratory | 1.17 | 0.997 – 1.36 | 0.0548 | 176 | 1757 | all | phecode |
| 512 | Other symptoms of respiratory system | Respiratory | 1.03 | 1.01 – 1.05 | 0.000821 | 18621 | 28154 | all | phecode |
| 512.1 | Wheezing | Respiratory | 1.11 | 1.05 – 1.17 | 0.000305 | 1409 | 13516 | all | phecode |
| 512.2 | Painful respiration | Respiratory | 1.04 | 0.991 – 1.08 | 0.124 | 2309 | 21263 | all | phecode |
| 512.3 | Abnormal chest sounds | Respiratory | 1.04 | 0.919 – 1.17 | 0.541 | 291 | 2845 | all | phecode |
| 512.7 | Shortness of breath | Respiratory | 1.05 | 1.03 – 1.08 | 1.3e-05 | 10034 | 28081 | all | phecode |
| 512.8 | Cough | Respiratory | 1.02 | 0.993 – 1.04 | 0.159 | 9501 | 28148 | all | phecode |
| 512.9 | Other dyspnea | Respiratory | 1.04 | 1.01 – 1.06 | 0.00228 | 10804 | 28104 | all | phecode |
| 513 | Respiratory abnormalities | Respiratory | 1.04 | 1.02 – 1.06 | 0.000255 | 12932 | 33822 | all | phecode |
| 513.3 | Hypoventilation | Respiratory | 1.06 | 0.983 – 1.13 | 0.133 | 880 | 8646 | all | phecode |
| 513.31 | Apnea | Respiratory | 1.06 | 0.96 – 1.17 | 0.253 | 462 | 4607 | all | phecode |
| 513.32 | Orthopnea | Respiratory | 1.07 | 0.928 – 1.23 | 0.35 | 220 | 2160 | all | phecode |
| 513.4 | Hyperventilation | Respiratory | 1.06 | 0.964 – 1.16 | 0.235 | 515 | 5124 | all | phecode |
| 513.8 | Disorders of diaphragm | Respiratory | 0.982 | 0.862 – 1.12 | 0.778 | 258 | 2557 | all | phecode |
| 514 | Abnormal findings examination of lungs | Respiratory | 1.08 | 1.04 – 1.11 | 1.23e-06 | 5365 | 34834 | all | phecode |
| 514.1 |
Abnormal results of function study of pulmonaryAbnormal results of function study of pulmonary system
|
Respiratory | 1.05 | 0.926 – 1.2 | 0.425 | 258 | 2580 | all | phecode |
| 514.2 | Solitary pulmonary nodule | Respiratory | 1.1 | 1.06 – 1.14 | 1.31e-06 | 3018 | 27338 | all | phecode |
| 516 | Abnormal sputum | Respiratory | 1.13 | 1.04 – 1.22 | 0.00218 | 735 | 7332 | all | phecode |
| 516.1 | Hemoptysis | Respiratory | 1.14 | 1.05 – 1.24 | 0.00255 | 611 | 6080 | all | phecode |
| 519 |
Other diseases of respiratory system, notOther diseases of respiratory system, not elsewhere classified
|
Respiratory | 1.04 | 1.01 – 1.07 | 0.00293 | 6458 | 39057 | all | phecode |
| 519.1 | Tracheostomy complications | Respiratory | 1.19 | 1.03 – 1.38 | 0.0209 | 214 | 2136 | all | phecode |
| 519.2 | Respiratory complications | Respiratory | 1.12 | 1.01 – 1.24 | 0.0259 | 445 | 4430 | all | phecode |
| 519.8 | Other diseases of respiratory system, NEC | Respiratory | 1.02 | 0.968 – 1.08 | 0.451 | 1588 | 15787 | all | phecode |
| 519.9 |
Symptoms involving respiratory system and otherSymptoms involving respiratory system and other chest symptoms
|
Respiratory | 1.05 | 1.01 – 1.08 | 0.00517 | 4706 | 34489 | all | phecode |
| 520 | Disorders of tooth development | Digestive | 1.08 | 0.968 – 1.2 | 0.173 | 369 | 3690 | all | phecode |
| 520.1 | Hereditary disturbances in tooth structure | Digestive | 1.24 | 1.05 – 1.46 | 0.0094 | 165 | 1642 | all | phecode |
| 520.2 | Disturbances in tooth eruption | Digestive | 0.938 | 0.816 – 1.08 | 0.371 | 218 | 2172 | all | phecode |
| 521 | Diseases of hard tissues of teeth | Digestive | 1.12 | 1.05 – 1.2 | 0.00139 | 898 | 8954 | all | phecode |
| 521.1 | Dental caries | Digestive | 1.13 | 1.05 – 1.22 | 0.000784 | 837 | 8349 | all | phecode |
| 521.2 | Dental abrasion, erosion and attrition | Digestive | 0.983 | 0.746 – 1.29 | 0.9 | 52 | 510 | all | phecode |
| 522 | Diseases of pulp and periapical tissues | Digestive | 1.11 | 1.02 – 1.22 | 0.0217 | 535 | 5340 | all | phecode |
| 522.5 | Periapical abscess | Digestive | 1.1 | 0.997 – 1.22 | 0.0565 | 459 | 4583 | all | phecode |
| 523 | Gingival and periodontal diseases | Digestive | 1.1 | 1.01 – 1.19 | 0.0242 | 718 | 7180 | all | phecode |
| 523.1 | Gingivitis | Digestive | 1.03 | 0.864 – 1.22 | 0.773 | 142 | 1418 | all | phecode |
| 523.3 | Periodontitis (acute or chronic) | Digestive | 1.14 | 1.02 – 1.27 | 0.0223 | 364 | 3636 | all | phecode |
| 523.31 | Acute periodontitis | Digestive | 1.13 | 1 – 1.28 | 0.0435 | 311 | 3109 | all | phecode |
| 523.32 | Chronic periodontitis | Digestive | 1.16 | 0.955 – 1.4 | 0.136 | 122 | 1204 | all | phecode |
| 524 | Dentofacial anomalies, including malocclusion | Digestive | 0.962 | 0.863 – 1.07 | 0.488 | 363 | 3630 | all | phecode |
| 524.3 | Anomalies of tooth position/malocclusion | Digestive | 0.901 | 0.784 – 1.03 | 0.139 | 220 | 2200 | all | phecode |
| 525 |
Other diseases of the teeth and supportingOther diseases of the teeth and supporting structures
|
Digestive | 1.16 | 1.08 – 1.23 | 1.44e-05 | 1039 | 10382 | all | phecode |
| 525.1 | Loss of teeth or edentulism | Digestive | 1.16 | 1.04 – 1.3 | 0.00748 | 374 | 3731 | all | phecode |
| 526 | Diseases of the jaws | Digestive | 0.995 | 0.955 – 1.04 | 0.801 | 2680 | 26455 | all | phecode |
| 526.1 | Cysts of the jaws | Digestive | 1.13 | 0.991 – 1.29 | 0.0689 | 247 | 2470 | all | phecode |
| 526.3 | Anomalies of jaw size/symmetry | Digestive | 1.02 | 0.89 – 1.16 | 0.811 | 241 | 2383 | all | phecode |
| 526.4 | Temporomandibular joint disorders | Digestive | 0.972 | 0.92 – 1.03 | 0.298 | 1504 | 15025 | all | phecode |
| 526.41 | Temporomandibular joint disorder, unspecified | Digestive | 0.972 | 0.914 – 1.03 | 0.364 | 1187 | 11858 | all | phecode |
| 526.42 | Arthralgia/ankylosis of temporomandibular joint | Digestive | 0.946 | 0.876 – 1.02 | 0.16 | 741 | 7400 | all | phecode |
| 526.5 | Inflammatory conditions of jaw | Digestive | 1.09 | 0.963 – 1.23 | 0.178 | 287 | 2864 | all | phecode |
| 526.8 | Exostosis of jaw | Digestive | 0.941 | 0.711 – 1.25 | 0.672 | 53 | 521 | all | phecode |
| 526.9 | Jaw disease NOS | Digestive | 0.953 | 0.867 – 1.05 | 0.323 | 487 | 4867 | all | phecode |
| 527 | Diseases of the salivary glands | Digestive | 0.995 | 0.946 – 1.05 | 0.831 | 1781 | 17771 | all | phecode |
| 527.1 | Hypertrophy of salivary gland | Digestive | 0.95 | 0.731 – 1.24 | 0.703 | 58 | 579 | all | phecode |
| 527.2 | Sialoadenitis | Digestive | 1.01 | 0.912 – 1.12 | 0.818 | 394 | 3936 | all | phecode |
| 527.7 | Disturbance of salivary secretion | Digestive | 0.937 | 0.875 – 1 | 0.0629 | 952 | 9481 | all | phecode |
| 527.8 | Other specified diseases of the salivary glands | Digestive | 1.05 | 0.927 – 1.2 | 0.418 | 254 | 2540 | all | phecode |
| 528 |
Diseases of the oral soft tissues, excludingDiseases of the oral soft tissues, excluding lesions specific for gingiva and tongue
|
Digestive | 0.99 | 0.95 – 1.03 | 0.634 | 2643 | 26197 | all | phecode |
| 528.1 | Stomatitis and mucositis | Digestive | 0.952 | 0.878 – 1.03 | 0.24 | 668 | 6657 | all | phecode |
| 528.11 | Stomatitis and mucositis (ulcerative) | Digestive | 1.03 | 0.893 – 1.19 | 0.688 | 211 | 2110 | all | phecode |
| 528.12 | Oral aphthae | Digestive | 0.912 | 0.79 – 1.05 | 0.21 | 215 | 2137 | all | phecode |
| 528.3 | Cellulitis and abscess of oral soft tissues | Digestive | 1.11 | 0.971 – 1.28 | 0.122 | 235 | 2338 | all | phecode |
| 528.4 | Cysts of oral soft tissues | Digestive | 0.952 | 0.788 – 1.15 | 0.608 | 124 | 1229 | all | phecode |
| 528.41 | Cyst of the salivary gland | Digestive | 0.963 | 0.763 – 1.22 | 0.752 | 77 | 760 | all | phecode |
| 528.5 | Diseases of lips | Digestive | 0.998 | 0.904 – 1.1 | 0.966 | 462 | 4602 | all | phecode |
| 528.6 | Leukoplakia of oral mucosa | Digestive | 1.12 | 0.936 – 1.33 | 0.219 | 137 | 1370 | all | phecode |
| 528.7 | Sialolithiasis | Digestive | 1.04 | 0.881 – 1.22 | 0.668 | 163 | 1623 | all | phecode |
| 529 | Diseases and other conditions of the tongue | Digestive | 1.03 | 0.951 – 1.12 | 0.467 | 690 | 6878 | all | phecode |
| 529.1 | Glossitis | Digestive | 0.988 | 0.824 – 1.19 | 0.899 | 129 | 1281 | all | phecode |
| 529.6 | Glossodynia | Digestive | 1.09 | 0.925 – 1.28 | 0.311 | 168 | 1652 | all | phecode |
| 530 | Diseases of esophagus | Digestive | 1.04 | 1.02 – 1.06 | 7.88e-05 | 17081 | 27931 | all | phecode |
| 530.1 | Esophagitis, GERD and related diseases | Digestive | 1.04 | 1.02 – 1.06 | 4.08e-05 | 16572 | 27931 | all | phecode |
| 530.11 | GERD | Digestive | 1.04 | 1.02 – 1.07 | 2.68e-05 | 16143 | 27929 | all | phecode |
| 530.12 | Ulcer of esophagus | Digestive | 1.09 | 0.977 – 1.21 | 0.127 | 400 | 3983 | all | phecode |
| 530.13 | Barrett's esophagus | Digestive | 1.1 | 1.02 – 1.19 | 0.0166 | 762 | 7584 | all | phecode |
| 530.14 | Reflux esophagitis | Digestive | 1.04 | 0.987 – 1.09 | 0.157 | 1900 | 17495 | all | phecode |
| 530.15 | Eosinophilic esophagitis | Digestive | 1.03 | 0.898 – 1.19 | 0.647 | 221 | 2210 | all | phecode |
| 530.2 | Esophageal bleeding (varices/hemorrhage) | Digestive | 1.1 | 1.01 – 1.2 | 0.0231 | 651 | 6473 | all | phecode |
| 530.3 | Stricture and stenosis of esophagus | Digestive | 1 | 0.934 – 1.07 | 0.972 | 911 | 8971 | all | phecode |
| 530.5 | Disorders of esophageal motility | Digestive | 1.05 | 0.961 – 1.15 | 0.277 | 548 | 5432 | all | phecode |
| 530.6 | Diverticulum of esophagus, acquired | Digestive | 0.933 | 0.776 – 1.12 | 0.458 | 129 | 1265 | all | phecode |
| 530.7 | Gastroesophageal laceration-hemorrhage syndrome | Digestive | 1.15 | 0.909 – 1.44 | 0.25 | 82 | 812 | all | phecode |
| 530.9 | Heartburn | Digestive | 1.03 | 0.98 – 1.09 | 0.223 | 1519 | 14928 | all | phecode |
| 531 | Peptic ulcer (excl. esophageal) | Digestive | 1.09 | 1.04 – 1.14 | 3e-04 | 2073 | 20617 | all | phecode |
| 531.1 | Hemorrhage from gastrointestinal ulcer | Digestive | 0.994 | 0.894 – 1.1 | 0.908 | 391 | 3883 | all | phecode |
| 531.2 | Gastric ulcer | Digestive | 1.06 | 0.994 – 1.12 | 0.0793 | 1201 | 11970 | all | phecode |
| 531.3 | Duodenal ulcer | Digestive | 1.04 | 0.943 – 1.14 | 0.441 | 467 | 4640 | all | phecode |
| 531.4 | Peptic ulcer, site unspecified | Digestive | 1.1 | 1.03 – 1.19 | 0.00804 | 804 | 8018 | all | phecode |
| 531.5 | Gastrojejunal ulcer | Digestive | 1.26 | 1.06 – 1.5 | 0.00796 | 150 | 1500 | all | phecode |
| 532 | Dysphagia | Digestive | 1.06 | 1.02 – 1.09 | 0.000413 | 5585 | 26852 | all | phecode |
| 535 | Gastritis and duodenitis | Digestive | 1.05 | 1.01 – 1.1 | 0.00856 | 2799 | 27335 | all | phecode |
| 535.1 | Acute gastritis | Digestive | 1.05 | 0.985 – 1.11 | 0.14 | 1178 | 11750 | all | phecode |
| 535.2 | Atrophic gastritis | Digestive | 1.02 | 0.911 – 1.14 | 0.718 | 344 | 3413 | all | phecode |
| 535.6 | Duodenitis | Digestive | 1.06 | 0.945 – 1.19 | 0.328 | 334 | 3337 | all | phecode |
| 535.8 | Other specified gastritis | Digestive | 1.06 | 0.977 – 1.15 | 0.159 | 638 | 6354 | all | phecode |
| 535.9 | Gastritis and duodenitis, NOS | Digestive | 1.07 | 1.01 – 1.13 | 0.0311 | 1255 | 12511 | all | phecode |
| 536 | Disorders of function of stomach | Digestive | 1.03 | 0.994 – 1.08 | 0.0927 | 2911 | 27685 | all | phecode |
| 536.3 | Gastroparesis | Digestive | 1.03 | 0.953 – 1.12 | 0.438 | 706 | 6901 | all | phecode |
| 536.7 |
Complications of gastrostomy, colostomy andComplications of gastrostomy, colostomy and enterostomy
|
Digestive | 1.08 | 0.975 – 1.2 | 0.139 | 407 | 4059 | all | phecode |
| 536.8 |
Dyspepsia and other specified disorders ofDyspepsia and other specified disorders of function of stomach
|
Digestive | 1.05 | 1 – 1.1 | 0.0437 | 2150 | 21094 | all | phecode |
| 537 | Other disorders of stomach and duodenum | Digestive | 1.04 | 1 – 1.08 | 0.029 | 3183 | 30048 | all | phecode |
| 537.1 | Lesions of stomach and duodenum | Digestive | 1.2 | 1.02 – 1.42 | 0.0247 | 173 | 1725 | all | phecode |
| 539 | Bariatric surgery | Digestive | 1.08 | 1.02 – 1.14 | 0.00668 | 1509 | 15074 | all | phecode |
| 540 | Appendiceal conditions | Digestive | 0.993 | 0.904 – 1.09 | 0.891 | 495 | 4948 | all | phecode |
| 540.1 | Appendicitis | Digestive | 0.968 | 0.874 – 1.07 | 0.536 | 425 | 4239 | all | phecode |
| 540.11 | Acute appendicitis | Digestive | 0.95 | 0.848 – 1.06 | 0.369 | 353 | 3511 | all | phecode |
| 550 | Abdominal hernia | Digestive | 1.03 | 0.998 – 1.05 | 0.0706 | 6768 | 37731 | all | phecode |
| 550.1 | Inguinal hernia | Digestive | 0.963 | 0.916 – 1.01 | 0.148 | 1744 | 16488 | all | phecode |
| 550.2 | Diaphragmatic hernia | Digestive | 1.05 | 1.01 – 1.09 | 0.0271 | 2817 | 25849 | all | phecode |
| 550.3 | Femoral hernia | Digestive | 1.09 | 0.909 – 1.31 | 0.344 | 131 | 1291 | all | phecode |
| 550.4 | Umbilical hernia | Digestive | 0.985 | 0.93 – 1.04 | 0.607 | 1313 | 13110 | all | phecode |
| 550.5 | Ventral hernia | Digestive | 1.04 | 0.998 – 1.09 | 0.0621 | 2241 | 22163 | all | phecode |
| 550.6 | Incisional hernia | Digestive | 1.07 | 1.01 – 1.14 | 0.02 | 1313 | 13111 | all | phecode |
| 555 |
Inflammatory bowel disease and otherInflammatory bowel disease and other gastroenteritis and colitis
|
Digestive | 1 | 0.949 – 1.06 | 0.967 | 1536 | 15153 | all | phecode |
| 555.1 | Regional enteritis | Digestive | 0.973 | 0.908 – 1.04 | 0.448 | 919 | 9095 | all | phecode |
| 555.2 | Ulcerative colitis | Digestive | 1 | 0.933 – 1.07 | 0.993 | 937 | 9315 | all | phecode |
| 555.21 | Ulcerative colitis (chronic) | Digestive | 0.965 | 0.881 – 1.06 | 0.442 | 537 | 5315 | all | phecode |
| 556 | Ulceration of the lower GI tract | Digestive | 0.949 | 0.873 – 1.03 | 0.223 | 632 | 6267 | all | phecode |
| 556.1 | Ulceration of intestine | Digestive | 0.964 | 0.882 – 1.06 | 0.43 | 551 | 5451 | all | phecode |
| 556.11 |
Angiodysplasia of intestine (without mention ofAngiodysplasia of intestine (without mention of hemorrhage)
|
Digestive | 0.942 | 0.817 – 1.09 | 0.407 | 214 | 2093 | all | phecode |
| 557 | Intestinal malabsorption (non-celiac) | Digestive | 1.02 | 0.966 – 1.07 | 0.515 | 1716 | 16490 | all | phecode |
| 557.1 | Celiac disease | Digestive | 0.984 | 0.889 – 1.09 | 0.759 | 421 | 4026 | all | phecode |
| 558 | Noninfectious gastroenteritis | Digestive | 1.03 | 0.995 – 1.07 | 0.0898 | 3458 | 26408 | all | phecode |
| 559 | Ileostomy status | Digestive | 1.08 | 1.01 – 1.16 | 0.025 | 957 | 9565 | all | phecode |
| 560 | Intestinal obstruction without mention of hernia | Digestive | 1.01 | 0.97 – 1.05 | 0.662 | 3004 | 24851 | all | phecode |
| 560.1 | Paralytic ileus | Digestive | 1.04 | 0.984 – 1.09 | 0.182 | 1627 | 15714 | all | phecode |
| 560.2 | Impaction of intestine | Digestive | 1.03 | 0.928 – 1.15 | 0.545 | 387 | 3779 | all | phecode |
| 560.3 | Peritoneal or intestinal adhesions | Digestive | 1.09 | 0.957 – 1.24 | 0.195 | 266 | 2647 | all | phecode |
| 560.4 | Other intestinal obstruction | Digestive | 1.01 | 0.957 – 1.06 | 0.752 | 1651 | 16170 | all | phecode |
| 561 | Symptoms involving digestive system | Digestive | 1.02 | 0.983 – 1.07 | 0.252 | 2608 | 21766 | all | phecode |
| 562 | Diverticulosis and diverticulitis | Digestive | 0.983 | 0.955 – 1.01 | 0.269 | 6295 | 23431 | all | phecode |
| 562.1 | Diverticulosis | Digestive | 0.983 | 0.954 – 1.01 | 0.259 | 6246 | 23383 | all | phecode |
| 562.2 | Diverticulitis | Digestive | 1.02 | 0.968 – 1.08 | 0.459 | 1611 | 15162 | all | phecode |
| 564 | Functional digestive disorders | Digestive | 1.01 | 0.991 – 1.04 | 0.229 | 11411 | 28676 | all | phecode |
| 564.1 | Irritable Bowel Syndrome | Digestive | 1.01 | 0.971 – 1.05 | 0.683 | 3457 | 22266 | all | phecode |
| 564.9 | Personal history of diseases of digestive system | Digestive | 1 | 0.965 – 1.04 | 0.893 | 3074 | 25861 | all | phecode |
| 565 | Anal and rectal conditions | Digestive | 1.01 | 0.977 – 1.05 | 0.466 | 3355 | 30757 | all | phecode |
| 565.1 | Anal and rectal polyp | Digestive | 0.998 | 0.941 – 1.06 | 0.941 | 1305 | 12649 | all | phecode |
| 567 | Peritonitis and retroperitoneal infections | Digestive | 1.04 | 0.98 – 1.1 | 0.201 | 1364 | 13616 | all | phecode |
| 568 | Other disorders of peritoneum | Digestive | 1.05 | 1 – 1.11 | 0.0415 | 1705 | 17038 | all | phecode |
| 568.1 |
Peritoneal adhesions (postoperative)Peritoneal adhesions (postoperative) (postinfection)
|
Digestive | 1.07 | 1 – 1.13 | 0.0347 | 1247 | 12468 | all | phecode |
| 569 | Other disorders of intestine | Digestive | 1.01 | 0.987 – 1.04 | 0.358 | 8079 | 35231 | all | phecode |
| 569.1 | Toxic gastroenteritis and colitis | Digestive | 0.992 | 0.885 – 1.11 | 0.894 | 326 | 3260 | all | phecode |
| 569.2 | Gastrointestinal complications | Digestive | 1.04 | 0.987 – 1.1 | 0.136 | 1395 | 13933 | all | phecode |
| 571 | Chronic liver disease and cirrhosis | Digestive | 1.01 | 0.981 – 1.05 | 0.452 | 4610 | 32562 | all | phecode |
| 571.5 | Other chronic nonalcoholic liver disease | Digestive | 1.01 | 0.979 – 1.04 | 0.509 | 4342 | 32234 | all | phecode |
| 571.51 | Cirrhosis of liver without mention of alcohol | Digestive | 1.06 | 0.992 – 1.13 | 0.0842 | 1018 | 10095 | all | phecode |
| 571.6 | Primary biliary cirrhosis | Digestive | 1.03 | 0.879 – 1.21 | 0.718 | 179 | 1790 | all | phecode |
| 571.8 |
Liver abscess and sequelae of chronic liverLiver abscess and sequelae of chronic liver disease
|
Digestive | 1.05 | 0.982 – 1.13 | 0.153 | 950 | 9498 | all | phecode |
| 571.81 | Portal hypertension | Digestive | 1.05 | 0.962 – 1.15 | 0.267 | 573 | 5730 | all | phecode |
| 572 | Ascites (non malignant) | Digestive | 1.04 | 0.996 – 1.09 | 0.0726 | 2278 | 22675 | all | phecode |
| 573 | Other disorders of liver | Digestive | 1.01 | 0.985 – 1.04 | 0.328 | 5599 | 33620 | all | phecode |
| 573.1 | Chronic passive congestion of liver | Digestive | 1.1 | 0.923 – 1.31 | 0.283 | 136 | 1359 | all | phecode |
| 573.2 | Liver replaced by transplant | Digestive | 1.07 | 0.943 – 1.21 | 0.299 | 292 | 2920 | all | phecode |
| 573.3 | Hepatomegaly | Digestive | 1.04 | 0.947 – 1.15 | 0.394 | 470 | 4700 | all | phecode |
| 573.4 | Acute and subacute necrosis of liver | Digestive | 1.01 | 0.897 – 1.13 | 0.905 | 316 | 3149 | all | phecode |
| 573.5 | Jaundice (not of newborn) | Digestive | 0.958 | 0.894 – 1.03 | 0.212 | 958 | 9496 | all | phecode |
| 573.6 |
Nonspecific elevation of levels of transaminaseNonspecific elevation of levels of transaminase or lactic acid dehydrogenase [LDH]
|
Digestive | 0.992 | 0.953 – 1.03 | 0.708 | 2756 | 26470 | all | phecode |
| 573.7 | Abnormal results of function study of liver | Digestive | 1.01 | 0.968 – 1.05 | 0.771 | 3018 | 27774 | all | phecode |
| 573.9 | Abnormal serum enzyme levels | Digestive | 1 | 0.969 – 1.03 | 0.978 | 4679 | 33866 | all | phecode |
| 574 | Cholelithiasis and cholecystitis | Digestive | 0.981 | 0.945 – 1.02 | 0.314 | 3177 | 30809 | all | phecode |
| 574.1 | Cholelithiasis | Digestive | 0.975 | 0.938 – 1.01 | 0.208 | 2924 | 28874 | all | phecode |
| 574.11 | Cholelithiasis with acute cholecystitis | Digestive | 0.982 | 0.877 – 1.1 | 0.749 | 342 | 3412 | all | phecode |
| 574.12 | Cholelithiasis with other cholecystitis | Digestive | 0.985 | 0.901 – 1.08 | 0.746 | 553 | 5501 | all | phecode |
| 574.2 | Calculus of bile duct | Digestive | 0.976 | 0.908 – 1.05 | 0.509 | 852 | 8503 | all | phecode |
| 574.3 | Cholecystitis without cholelithiasis | Digestive | 0.953 | 0.886 – 1.03 | 0.202 | 822 | 8181 | all | phecode |
| 575 | Other biliary tract disease | Digestive | 1 | 0.957 – 1.04 | 0.985 | 2266 | 22555 | all | phecode |
| 575.1 | Cholangitis | Digestive | 1.07 | 0.96 – 1.19 | 0.218 | 354 | 3530 | all | phecode |
| 575.2 | Obstruction of bile duct | Digestive | 1.04 | 0.96 – 1.14 | 0.312 | 621 | 6201 | all | phecode |
| 575.6 | Cholesterolosis of gallbladder | Digestive | 0.93 | 0.803 – 1.08 | 0.329 | 207 | 2063 | all | phecode |
| 575.7 | Other disorders of gallbladder | Digestive | 0.967 | 0.903 – 1.04 | 0.338 | 939 | 9382 | all | phecode |
| 575.8 | Other disorders of biliary tract | Digestive | 1.04 | 0.974 – 1.1 | 0.261 | 1154 | 11523 | all | phecode |
| 575.9 |
Nonspecific abnormal findings on radiologicalNonspecific abnormal findings on radiological and other examination of biliary tract
|
Digestive | 1.17 | 1.03 – 1.33 | 0.0152 | 260 | 2600 | all | phecode |
| 577 | Diseases of pancreas | Digestive | 1.06 | 1.02 – 1.11 | 0.00709 | 2225 | 22106 | all | phecode |
| 577.1 | Acute pancreatitis | Digestive | 1.12 | 1.06 – 1.19 | 0.000147 | 1212 | 12110 | all | phecode |
| 577.2 | Chronic pancreatitis | Digestive | 1.12 | 1.02 – 1.23 | 0.0176 | 495 | 4950 | all | phecode |
| 577.3 | Cyst and pseudocyst of pancreas | Digestive | 1.07 | 0.977 – 1.17 | 0.145 | 570 | 5601 | all | phecode |
| 578 | Gastrointestinal hemorrhage | Digestive | 1.02 | 0.992 – 1.06 | 0.146 | 4554 | 37045 | all | phecode |
| 578.1 | Hematemesis | Digestive | 1.12 | 1.02 – 1.23 | 0.0219 | 485 | 4842 | all | phecode |
| 578.2 | Blood in stool | Digestive | 1.02 | 0.982 – 1.06 | 0.286 | 2743 | 26554 | all | phecode |
| 578.8 | Hemorrhage of rectum and anus | Digestive | 1.04 | 0.998 – 1.09 | 0.0638 | 2210 | 21750 | all | phecode |
| 578.9 | Hemorrhage of gastrointestinal tract | Digestive | 1.06 | 1 – 1.11 | 0.0425 | 1562 | 15345 | all | phecode |
| 579 | Other symptoms involving abdomen and pelvis | Digestive | 1.04 | 1.01 – 1.07 | 0.0147 | 4431 | 34209 | all | phecode |
| 579.2 | Splenomegaly | Digestive | 1.06 | 0.982 – 1.15 | 0.131 | 730 | 7262 | all | phecode |
| 579.8 | Nonspecific abnormal findings in stool contents | Digestive | 0.998 | 0.944 – 1.06 | 0.953 | 1410 | 13877 | all | phecode |
| 580 | Nephritis; nephrosis; renal sclerosis | Genitourinary | 1.07 | 1.02 – 1.12 | 0.00803 | 1881 | 15516 | all | phecode |
| 580.1 | Glomerulonephritis | Genitourinary | 1.03 | 0.929 – 1.14 | 0.573 | 401 | 3992 | all | phecode |
| 580.11 | Proliferative glomerulonephritis | Genitourinary | 1.07 | 0.904 – 1.26 | 0.435 | 146 | 1440 | all | phecode |
| 580.12 | Non-proliferative glomerulonephritis | Genitourinary | 1.06 | 0.875 – 1.29 | 0.545 | 114 | 1128 | all | phecode |
| 580.13 | Acute glomerulonephritis, NOS | Genitourinary | 1.06 | 0.81 – 1.38 | 0.677 | 61 | 600 | all | phecode |
| 580.14 | Chronic glomerulonephritis, NOS | Genitourinary | 1.02 | 0.903 – 1.16 | 0.724 | 277 | 2760 | all | phecode |
| 580.2 |
Nephrotic syndrome without mention ofNephrotic syndrome without mention of glomerulonephritis
|
Genitourinary | 1.05 | 0.914 – 1.21 | 0.48 | 221 | 2193 | all | phecode |
| 580.3 |
Nephritis and nephropathy without mention ofNephritis and nephropathy without mention of glomerulonephritis
|
Genitourinary | 1.06 | 1 – 1.12 | 0.033 | 1502 | 11930 | all | phecode |
| 580.31 |
Nephritis and nephropathy in diseasesNephritis and nephropathy in diseases classified elsewhere
|
Genitourinary | 1.02 | 0.954 – 1.1 | 0.529 | 992 | 7228 | all | phecode |
| 580.32 |
Nephritis and nephropathy with pathologicalNephritis and nephropathy with pathological lesion
|
Genitourinary | 1.07 | 0.992 – 1.16 | 0.0788 | 683 | 6612 | all | phecode |
| 580.4 | Renal sclerosis, NOS | Genitourinary | 1.06 | 0.947 – 1.19 | 0.313 | 340 | 3400 | all | phecode |
| 585 | Renal failure | Genitourinary | 1.06 | 1.03 – 1.09 | 2.28e-05 | 7470 | 32340 | all | phecode |
| 585.1 | Acute renal failure | Genitourinary | 1.07 | 1.04 – 1.11 | 4.26e-05 | 4265 | 27230 | all | phecode |
| 585.2 | Renal failure NOS | Genitourinary | 1.01 | 0.941 – 1.09 | 0.745 | 832 | 8162 | all | phecode |
| 585.3 | Chronic renal failure [CKD] | Genitourinary | 1.05 | 1.02 – 1.09 | 0.000578 | 5580 | 29470 | all | phecode |
| 585.31 | Renal dialysis | Genitourinary | 1.05 | 0.973 – 1.14 | 0.202 | 747 | 7423 | all | phecode |
| 585.32 | End stage renal disease | Genitourinary | 1.04 | 0.972 – 1.11 | 0.259 | 1007 | 9783 | all | phecode |
| 585.33 | Chronic Kidney Disease, Stage III | Genitourinary | 1.06 | 1.02 – 1.1 | 0.0051 | 3209 | 21312 | all | phecode |
| 585.34 | Chronic Kidney Disease, Stage IV | Genitourinary | 1.02 | 0.955 – 1.09 | 0.541 | 977 | 9190 | all | phecode |
| 585.4 | Chronic kidney disease, Stage I or II | Genitourinary | 1.11 | 1.04 – 1.18 | 0.000896 | 1227 | 11191 | all | phecode |
| 586 | Other disorders of the kidney and ureters | Genitourinary | 1.04 | 1.01 – 1.06 | 0.00602 | 7628 | 34189 | all | phecode |
| 586.1 | Anatomical abnormatilies of kidney and ureters | Genitourinary | 1.05 | 0.94 – 1.17 | 0.387 | 349 | 3480 | all | phecode |
| 586.11 | Small kidney | Genitourinary | 1.11 | 0.961 – 1.27 | 0.158 | 210 | 2093 | all | phecode |
| 586.12 | Vesicoureteral reflux | Genitourinary | 0.993 | 0.83 – 1.19 | 0.943 | 136 | 1360 | all | phecode |
| 586.2 | Cyst of kidney, acquired | Genitourinary | 1 | 0.946 – 1.06 | 0.971 | 1381 | 12912 | all | phecode |
| 586.3 | Vascular disorders of kidney/hypertrophy | Genitourinary | 1.16 | 0.998 – 1.35 | 0.0527 | 187 | 1862 | all | phecode |
| 586.4 | Stricture/obstruction of ureter | Genitourinary | 1.05 | 0.999 – 1.1 | 0.0568 | 1821 | 17115 | all | phecode |
| 587 | Kidney replaced by transpant | Genitourinary | 1.05 | 0.979 – 1.13 | 0.166 | 819 | 8134 | all | phecode |
| 588 | Disorders resulting from impaired renal function | Genitourinary | 1.02 | 0.956 – 1.09 | 0.517 | 976 | 9389 | all | phecode |
| 588.1 | Renal osteodystrophy | Genitourinary | 1.09 | 0.961 – 1.23 | 0.186 | 290 | 2900 | all | phecode |
| 588.2 | Secondary hyperparathyroidism (of renal origin) | Genitourinary | 1.01 | 0.935 – 1.09 | 0.814 | 755 | 7275 | all | phecode |
| 589 | Abnormal results of function study of kidney | Genitourinary | 0.995 | 0.931 – 1.06 | 0.893 | 1007 | 9834 | all | phecode |
| 590 | Pyelonephritis | Genitourinary | 1.06 | 1 – 1.12 | 0.0441 | 1461 | 14350 | all | phecode |
| 591 | Urinary tract infection | Genitourinary | 1.01 | 0.984 – 1.03 | 0.531 | 9873 | 32513 | all | phecode |
| 592 | Cystitis and urethritis | Genitourinary | 1.01 | 0.972 – 1.05 | 0.6 | 3038 | 24207 | all | phecode |
| 592.1 | Cystitis | Genitourinary | 1.01 | 0.969 – 1.05 | 0.659 | 2880 | 23279 | all | phecode |
| 592.11 | Acute cystitis | Genitourinary | 0.973 | 0.925 – 1.02 | 0.284 | 1783 | 16452 | all | phecode |
| 592.12 | Chronic cystitis | Genitourinary | 1.01 | 0.882 – 1.15 | 0.925 | 239 | 2343 | all | phecode |
| 592.13 | Chronic interstitial cystitis | Genitourinary | 1.1 | 0.99 – 1.21 | 0.0764 | 431 | 4310 | all | phecode |
| 592.2 | Urethritis and urethral syndrome | Genitourinary | 1.07 | 0.922 – 1.23 | 0.386 | 210 | 2093 | all | phecode |
| 593 | Hematuria | Genitourinary | 1.01 | 0.98 – 1.04 | 0.472 | 4859 | 32063 | all | phecode |
| 593.1 | Gross hematuria | Genitourinary | 1.01 | 0.956 – 1.06 | 0.762 | 1585 | 14824 | all | phecode |
| 593.2 | Microscopic hematuria | Genitourinary | 0.996 | 0.934 – 1.06 | 0.911 | 1049 | 10301 | all | phecode |
| 594 | Urinary calculus | Genitourinary | 1.04 | 1.02 – 1.07 | 0.00158 | 6707 | 38209 | all | phecode |
| 594.1 | Calculus of kidney | Genitourinary | 1.04 | 1.01 – 1.07 | 0.00378 | 6273 | 38051 | all | phecode |
| 594.2 | Calculus of lower urinary tract | Genitourinary | 1.01 | 0.904 – 1.13 | 0.876 | 366 | 3638 | all | phecode |
| 594.3 | Calculus of ureter | Genitourinary | 1.02 | 0.965 – 1.08 | 0.456 | 1361 | 13561 | all | phecode |
| 594.8 | Renal colic | Genitourinary | 1.01 | 0.902 – 1.13 | 0.882 | 356 | 3560 | all | phecode |
| 595 | Hydronephrosis | Genitourinary | 1.05 | 0.996 – 1.1 | 0.0697 | 1670 | 16658 | all | phecode |
| 596 | Other disorders of bladder | Genitourinary | 1.04 | 1 – 1.08 | 0.0295 | 3074 | 28020 | all | phecode |
| 596.1 | Bladder neck obstruction | Genitourinary | 0.98 | 0.884 – 1.09 | 0.708 | 400 | 3942 | all | phecode |
| 596.5 | Functional disorders of bladder | Genitourinary | 1.04 | 0.985 – 1.09 | 0.165 | 1719 | 17049 | all | phecode |
| 597 | Other disorders of urethra and urinary tract | Genitourinary | 1.02 | 0.956 – 1.08 | 0.618 | 1211 | 11998 | all | phecode |
| 597.1 | Urethral stricture (not specified as infectious) | Genitourinary | 0.994 | 0.916 – 1.08 | 0.885 | 661 | 6537 | all | phecode |
| 597.2 | Urinary complications NEC | Genitourinary | 1.04 | 0.972 – 1.11 | 0.267 | 1049 | 10479 | all | phecode |
| 597.8 | Urethral hypermobility/ISD | Genitourinary | 1.05 | 0.903 – 1.23 | 0.504 | 189 | 1873 | all | phecode |
| 598 | Abnormal findings on examination of urine | Genitourinary | 0.966 | 0.806 – 1.16 | 0.708 | 138 | 1356 | all | phecode |
| 598.4 | Other cells and casts in urine | Genitourinary | 0.942 | 0.778 – 1.14 | 0.542 | 122 | 1192 | all | phecode |
| 599 | Other symptoms/disorders or the urinary system | Genitourinary | 0.989 | 0.969 – 1.01 | 0.3 | 14168 | 30681 | all | phecode |
| 599.1 | Urinary obstruction | Genitourinary | 1.01 | 0.933 – 1.09 | 0.826 | 728 | 6861 | all | phecode |
| 599.2 | Retention of urine | Genitourinary | 0.998 | 0.967 – 1.03 | 0.921 | 5034 | 28305 | all | phecode |
| 599.3 | Dysuria | Genitourinary | 0.982 | 0.951 – 1.02 | 0.293 | 4397 | 27849 | all | phecode |
| 599.4 | Urinary incontinence | Genitourinary | 1.02 | 0.988 – 1.05 | 0.234 | 5599 | 26960 | all | phecode |
| 599.5 | Frequency of urination and polyuria | Genitourinary | 0.977 | 0.948 – 1.01 | 0.122 | 5498 | 28723 | all | phecode |
| 599.6 | Oliguria and anuria | Genitourinary | 1.09 | 0.997 – 1.18 | 0.06 | 599 | 5902 | all | phecode |
| 599.7 | Urethral discharge | Genitourinary | 0.832 | 0.681 – 1.02 | 0.0729 | 118 | 1175 | all | phecode |
| 599.8 | Other symptoms involving urinary system | Genitourinary | 0.994 | 0.965 – 1.02 | 0.714 | 5446 | 27963 | all | phecode |
| 599.9 | Other abnormality of urination | Genitourinary | 0.991 | 0.953 – 1.03 | 0.633 | 3041 | 24877 | all | phecode |
| 600 | Hyperplasia of prostate | Genitourinary | 0.962 | 0.924 – 1 | 0.0503 | 4063 | 11364 | all | phecode |
| 601 | Inflammatory diseases of prostate | Genitourinary | 0.875 | 0.82 – 0.934 | 6.29e-05 | 1044 | 9665 | all | phecode |
| 601.1 | Prostatitis | Genitourinary | 0.841 | 0.764 – 0.926 | 0.000394 | 477 | 4596 | all | phecode |
| 601.11 | Acute prostatitis | Genitourinary | 0.959 | 0.792 – 1.16 | 0.668 | 124 | 1200 | all | phecode |
| 601.12 | Chronic prostatitis | Genitourinary | 0.715 | 0.579 – 0.883 | 0.00181 | 95 | 943 | all | phecode |
| 601.3 | Orchitis and epididymitis | Genitourinary | 0.916 | 0.824 – 1.02 | 0.102 | 389 | 3822 | all | phecode |
| 601.4 | Balanoposthitis | Genitourinary | 0.944 | 0.787 – 1.13 | 0.533 | 127 | 1224 | all | phecode |
| 601.8 |
Other inflammatory disorders of male genitalOther inflammatory disorders of male genital organs
|
Genitourinary | 0.959 | 0.814 – 1.13 | 0.613 | 161 | 1591 | all | phecode |
| 602 | Other disorders of prostate | Genitourinary | 0.862 | 0.772 – 0.963 | 0.00839 | 361 | 3399 | all | phecode |
| 602.3 | Dysplasia of prostate | Genitourinary | 0.845 | 0.67 – 1.06 | 0.153 | 77 | 730 | all | phecode |
| 603 | Other disorders of testis | Genitourinary | 1.08 | 0.982 – 1.2 | 0.11 | 440 | 4354 | all | phecode |
| 603.1 | Hydrocele | Genitourinary | 1.05 | 0.934 – 1.19 | 0.394 | 293 | 2882 | all | phecode |
| 603.2 | Spermatocele | Genitourinary | 1.18 | 0.999 – 1.4 | 0.0513 | 156 | 1539 | all | phecode |
| 604 | Disorders of penis | Genitourinary | 0.951 | 0.878 – 1.03 | 0.215 | 685 | 6748 | all | phecode |
| 604.1 | Redundant prepuce and phimosis/BXO | Genitourinary | 1.03 | 0.873 – 1.21 | 0.741 | 155 | 1540 | all | phecode |
| 604.3 | Peyronie's disease | Genitourinary | 1.03 | 0.89 – 1.18 | 0.718 | 215 | 2132 | all | phecode |
| 605 | Erectile dysfunction [ED] | Genitourinary | 0.958 | 0.922 – 0.995 | 0.0283 | 3776 | 12700 | all | phecode |
| 608 | Other disorders of male genital organs | Genitourinary | 0.989 | 0.939 – 1.04 | 0.687 | 1645 | 13758 | all | phecode |
| 609 | Male infertility and abnormal spermatozoa | Genitourinary | 0.859 | 0.776 – 0.952 | 0.00379 | 424 | 4196 | all | phecode |
| 609.1 | Infertility, male | Genitourinary | 0.855 | 0.758 – 0.965 | 0.0113 | 302 | 2992 | all | phecode |
| 609.11 | Azoospermia and oligospermia | Genitourinary | 0.936 | 0.757 – 1.16 | 0.542 | 95 | 950 | all | phecode |
| 609.2 | Abnormal spermatozoa | Genitourinary | 0.803 | 0.678 – 0.95 | 0.0105 | 154 | 1519 | all | phecode |
| 610 | Benign mammary dysplasias | Genitourinary | 0.931 | 0.897 – 0.966 | 0.000144 | 3683 | 16548 | all | phecode |
| 610.1 | Cystic mastopathy | Genitourinary | 0.925 | 0.878 – 0.975 | 0.00381 | 1633 | 14191 | all | phecode |
| 610.2 | Fibroadenosis of breast | Genitourinary | 0.737 | 0.563 – 0.965 | 0.0264 | 60 | 600 | all | phecode |
| 610.4 | Benign neoplasm of breast | Genitourinary | 0.921 | 0.883 – 0.96 | 8.98e-05 | 2837 | 16430 | all | phecode |
| 610.8 | Other specified benign mammary dysplasias | Genitourinary | 0.924 | 0.871 – 0.98 | 0.00897 | 1269 | 12191 | all | phecode |
| 611 | Abnormal findings on mammogram or breast exam | Genitourinary | 0.952 | 0.923 – 0.981 | 0.00141 | 6067 | 18690 | all | phecode |
| 611.1 | Abnormal mammogram | Genitourinary | 0.938 | 0.908 – 0.97 | 0.000165 | 4980 | 16120 | all | phecode |
| 611.11 | Mammographic microcalcification | Genitourinary | 0.893 | 0.838 – 0.952 | 0.000498 | 1122 | 10394 | all | phecode |
| 611.3 | Lump or mass in breast | Genitourinary | 0.964 | 0.929 – 1 | 0.0549 | 3549 | 18572 | all | phecode |
| 612 |
Breast conditions, congenital or relating toBreast conditions, congenital or relating to hormones
|
Genitourinary | 0.962 | 0.901 – 1.03 | 0.25 | 1051 | 10425 | all | phecode |
| 612.1 | Galactorrhea | Genitourinary | 0.915 | 0.768 – 1.09 | 0.315 | 139 | 1390 | all | phecode |
| 612.2 | Hypertrophy of breast (Gynecomastia) | Genitourinary | 0.964 | 0.894 – 1.04 | 0.339 | 800 | 7962 | all | phecode |
| 612.3 | Congenital anomalies of breast | Genitourinary | 0.95 | 0.756 – 1.2 | 0.663 | 83 | 810 | all | phecode |
| 613 | Other nonmalignant breast conditions | Genitourinary | 0.996 | 0.962 – 1.03 | 0.843 | 3897 | 22072 | all | phecode |
| 613.1 | Inflammatory disease of breast | Genitourinary | 1.02 | 0.938 – 1.11 | 0.62 | 593 | 5874 | all | phecode |
| 613.5 | Mastodynia | Genitourinary | 1.02 | 0.972 – 1.08 | 0.375 | 1675 | 16203 | all | phecode |
| 613.7 | Other signs and symptoms in breast | Genitourinary | 0.993 | 0.926 – 1.07 | 0.847 | 883 | 8754 | all | phecode |
| 613.8 | Other specified disorders of breast | Genitourinary | 1.03 | 0.957 – 1.1 | 0.475 | 932 | 9248 | all | phecode |
| 613.9 | Breast disorder NOS | Genitourinary | 0.967 | 0.915 – 1.02 | 0.239 | 1465 | 14174 | all | phecode |
| 614 | Inflammatory diseases of female pelvic organs | Genitourinary | 0.995 | 0.959 – 1.03 | 0.774 | 3715 | 19647 | all | phecode |
| 614.1 |
Pelvic peritoneal adhesions, femalePelvic peritoneal adhesions, female (postoperative) (postinfection)
|
Genitourinary | 0.963 | 0.86 – 1.08 | 0.519 | 337 | 3370 | all | phecode |
| 614.3 | Pelvic inflammatory disease (PID) | Genitourinary | 1.05 | 0.955 – 1.16 | 0.307 | 478 | 4773 | all | phecode |
| 614.31 | Acute inflammatory pelvic disease | Genitourinary | 1.06 | 0.859 – 1.31 | 0.581 | 94 | 933 | all | phecode |
| 614.32 | Chronic inflammatory pelvic disease | Genitourinary | 0.991 | 0.849 – 1.16 | 0.912 | 186 | 1842 | all | phecode |
| 614.33 | Pelvic inflammatory disease, NOS | Genitourinary | 1.11 | 0.968 – 1.26 | 0.14 | 246 | 2460 | all | phecode |
| 614.4 | Inflammatory diseases of uterus, except cervix | Genitourinary | 1.1 | 0.933 – 1.3 | 0.257 | 165 | 1639 | all | phecode |
| 614.5 |
Inflammatory disease of cervix, vagina, andInflammatory disease of cervix, vagina, and vulva
|
Genitourinary | 0.997 | 0.959 – 1.04 | 0.863 | 3180 | 19539 | all | phecode |
| 614.51 | Cervicitis and endocervicitis | Genitourinary | 1.04 | 0.91 – 1.18 | 0.594 | 264 | 2640 | all | phecode |
| 614.52 | Vaginitis and vulvovaginitis | Genitourinary | 0.985 | 0.945 – 1.03 | 0.485 | 2732 | 18924 | all | phecode |
| 614.53 | Cyst or abscess of Bartholin's gland | Genitourinary | 1.08 | 0.902 – 1.3 | 0.397 | 132 | 1311 | all | phecode |
| 614.54 | Abscess or ulceration of vulva | Genitourinary | 0.992 | 0.866 – 1.14 | 0.909 | 225 | 2244 | all | phecode |
| 615 | Endometriosis | Genitourinary | 1.01 | 0.956 – 1.06 | 0.769 | 1585 | 14666 | all | phecode |
| 618 | Genital prolapse | Genitourinary | 0.995 | 0.95 – 1.04 | 0.84 | 2079 | 17915 | all | phecode |
| 618.1 | Prolapse of vaginal walls | Genitourinary | 0.981 | 0.927 – 1.04 | 0.519 | 1408 | 13456 | all | phecode |
| 618.2 | Uterine/Uterovaginal prolapse | Genitourinary | 0.949 | 0.865 – 1.04 | 0.261 | 542 | 5390 | all | phecode |
| 618.5 | Prolapse of vaginal vault after hysterectomy | Genitourinary | 0.973 | 0.865 – 1.1 | 0.655 | 317 | 3162 | all | phecode |
| 618.6 | Vaginal enterocele, congenital or acquired | Genitourinary | 1.04 | 0.938 – 1.15 | 0.473 | 441 | 4394 | all | phecode |
| 619 | Noninflammatory female genital disorders | Genitourinary | 0.987 | 0.957 – 1.02 | 0.393 | 5728 | 18687 | all | phecode |
| 619.1 |
Noninflammatory disorders of ovary, fallopianNoninflammatory disorders of ovary, fallopian tube, and broad ligament
|
Genitourinary | 0.972 | 0.915 – 1.03 | 0.353 | 1233 | 12082 | all | phecode |
| 619.2 | Disorders of uterus, NEC | Genitourinary | 0.976 | 0.895 – 1.06 | 0.575 | 591 | 5897 | all | phecode |
| 619.3 | Noninflammatory disorders of cervix | Genitourinary | 0.969 | 0.881 – 1.07 | 0.519 | 483 | 4823 | all | phecode |
| 619.4 | Noninflammatory disorders of vagina | Genitourinary | 1.02 | 0.976 – 1.06 | 0.387 | 2525 | 18404 | all | phecode |
| 619.5 | Noninflammatory disorders of vulva and perineum | Genitourinary | 0.985 | 0.927 – 1.05 | 0.639 | 1189 | 11717 | all | phecode |
| 620 | Dysplasia of female genital organs | Genitourinary | 1.02 | 0.917 – 1.13 | 0.725 | 395 | 3950 | all | phecode |
| 620.1 | Dysplasia of cervix | Genitourinary | 0.927 | 0.794 – 1.08 | 0.341 | 178 | 1780 | all | phecode |
| 621 | Endometrial hyperplasia | Genitourinary | 0.931 | 0.841 – 1.03 | 0.171 | 437 | 4370 | all | phecode |
| 622 | Polyp of female genital organs | Genitourinary | 0.931 | 0.881 – 0.985 | 0.0122 | 1449 | 14264 | all | phecode |
| 622.1 | Polyp of corpus uteri | Genitourinary | 0.938 | 0.88 – 0.999 | 0.0456 | 1132 | 11189 | all | phecode |
| 622.2 | Mucous polyp of cervix | Genitourinary | 0.868 | 0.785 – 0.959 | 0.00538 | 445 | 4444 | all | phecode |
| 623 | Hypertrophy of female genital organs | Genitourinary | 1.01 | 0.938 – 1.09 | 0.787 | 824 | 8165 | all | phecode |
| 624 | Symptoms involving female genital tract | Genitourinary | 1.05 | 0.988 – 1.11 | 0.12 | 1348 | 12518 | all | phecode |
| 624.1 | Dystrophy of female genital tract | Genitourinary | 0.931 | 0.808 – 1.07 | 0.321 | 216 | 2155 | all | phecode |
| 624.2 | Atrophy of female genital tract | Genitourinary | 0.901 | 0.694 – 1.17 | 0.432 | 64 | 615 | all | phecode |
| 624.9 | stress incontinence, female | Genitourinary | 1.04 | 0.992 – 1.09 | 0.1 | 1935 | 15408 | all | phecode |
| 625 |
Pain and other symptoms associated with femalePain and other symptoms associated with female genital organs
|
Genitourinary | 1 | 0.973 – 1.04 | 0.798 | 5653 | 17303 | all | phecode |
| 625.1 | Dyspareunia | Genitourinary | 1.03 | 0.967 – 1.09 | 0.385 | 1267 | 12474 | all | phecode |
| 626 |
Disorders of menstruation and other abnormalDisorders of menstruation and other abnormal bleeding from female genital tract
|
Genitourinary | 0.97 | 0.939 – 1 | 0.0551 | 5940 | 15585 | all | phecode |
| 626.1 | Irregular menstrual cycle/bleeding | Genitourinary | 0.962 | 0.929 – 0.997 | 0.0351 | 4315 | 14604 | all | phecode |
| 626.11 | Absent or infrequent menstruation | Genitourinary | 0.972 | 0.91 – 1.04 | 0.394 | 1062 | 8531 | all | phecode |
| 626.12 | Excessive or frequent menstruation | Genitourinary | 0.953 | 0.909 – 1 | 0.0497 | 2097 | 11991 | all | phecode |
| 626.13 | Irregular menstrual cycle | Genitourinary | 0.961 | 0.915 – 1.01 | 0.112 | 1957 | 12265 | all | phecode |
| 626.14 | Irregular menstrual bleeding | Genitourinary | 0.953 | 0.891 – 1.02 | 0.168 | 970 | 8996 | all | phecode |
| 626.15 | Infertility, female, associated with anovulation | Genitourinary | 1.01 | 0.907 – 1.12 | 0.908 | 394 | 3789 | all | phecode |
| 626.2 | Dysmenorrhea | Genitourinary | 1 | 0.947 – 1.06 | 0.9 | 1373 | 9857 | all | phecode |
| 626.4 | Premenstrual tension syndromes | Genitourinary | 0.991 | 0.883 – 1.11 | 0.872 | 336 | 3308 | all | phecode |
| 626.8 | Infertility, female | Genitourinary | 0.909 | 0.844 – 0.979 | 0.0115 | 817 | 6741 | all | phecode |
| 627 | Menopausal and postmenopausal disorders | Genitourinary | 0.967 | 0.934 – 1 | 0.0557 | 4560 | 14557 | all | phecode |
| 627.1 | Postmenopausal bleeding | Genitourinary | 0.968 | 0.908 – 1.03 | 0.308 | 1146 | 10338 | all | phecode |
| 627.2 | Symptomatic menopause | Genitourinary | 0.956 | 0.918 – 0.996 | 0.0321 | 3017 | 13763 | all | phecode |
| 627.21 | Symptomatic artificial menopause | Genitourinary | 0.963 | 0.816 – 1.14 | 0.661 | 152 | 1514 | all | phecode |
| 627.22 |
Need for Hormone replacement therapyNeed for Hormone replacement therapy (postmenopausal)
|
Genitourinary | 0.874 | 0.782 – 0.978 | 0.019 | 356 | 3513 | all | phecode |
| 627.3 | Postmenopausal atrophic vaginitis | Genitourinary | 0.893 | 0.834 – 0.955 | 0.00104 | 997 | 9484 | all | phecode |
| 627.4 | Premenopausal menorrhagia | Genitourinary | 0.996 | 0.892 – 1.11 | 0.947 | 361 | 3580 | all | phecode |
| 627.5 | Premature menopause and other ovarian failure | Genitourinary | 0.893 | 0.793 – 1.01 | 0.061 | 309 | 3082 | all | phecode |
| 628 | Ovarian cyst | Genitourinary | 0.959 | 0.914 – 1.01 | 0.0956 | 1945 | 13838 | all | phecode |
| 634 | Miscarriage; stillbirth | Pregnancy Complications | 0.969 | 0.901 – 1.04 | 0.395 | 826 | 8047 | all | phecode |
| 634.1 | Missed abortion/Hydatidiform mole | Pregnancy Complications | 0.903 | 0.797 – 1.02 | 0.113 | 273 | 2715 | all | phecode |
| 634.3 | Ectopic pregnancy | Pregnancy Complications | 1.09 | 0.899 – 1.32 | 0.38 | 117 | 1170 | all | phecode |
| 635 |
Hemorrhage during pregnancy; childbirth andHemorrhage during pregnancy; childbirth and postpartum
|
Pregnancy Complications | 0.989 | 0.906 – 1.08 | 0.796 | 563 | 5309 | all | phecode |
| 635.2 |
Antepartum hemorrhage, abruptio placentae, andAntepartum hemorrhage, abruptio placentae, and placenta previa
|
Pregnancy Complications | 1 | 0.898 – 1.11 | 0.996 | 370 | 3629 | all | phecode |
| 635.3 | Placenta previa and abruptio placenta | Pregnancy Complications | 0.954 | 0.845 – 1.08 | 0.447 | 288 | 2850 | all | phecode |
| 636 |
Early or threatened labor; hemorrhage in earlyEarly or threatened labor; hemorrhage in early pregnancy
|
Pregnancy Complications | 1.01 | 0.946 – 1.08 | 0.771 | 1080 | 7870 | all | phecode |
| 636.1 | Threatened premature labor | Pregnancy Complications | 1.09 | 0.978 – 1.21 | 0.122 | 380 | 3799 | all | phecode |
| 636.2 | Early onset of delivery | Pregnancy Complications | 1.01 | 0.893 – 1.14 | 0.887 | 288 | 2868 | all | phecode |
| 636.3 | Hemorrhage in early pregnancy | Pregnancy Complications | 0.995 | 0.902 – 1.1 | 0.926 | 441 | 4365 | all | phecode |
| 636.8 | Cervical incompetence | Pregnancy Complications | 1.12 | 0.887 – 1.42 | 0.339 | 77 | 770 | all | phecode |
| 637 |
Short gestation; low birth weight; and fetalShort gestation; low birth weight; and fetal growth retardation
|
Pregnancy Complications | 1.2 | 0.964 – 1.5 | 0.103 | 85 | 850 | all | phecode |
| 642 |
Hypertension complicating pregnancyHypertension complicating pregnancy, childbirth, and the puerperium
|
Pregnancy Complications | 0.993 | 0.911 – 1.08 | 0.875 | 585 | 5725 | all | phecode |
| 642.1 | Preeclampsia and eclampsia | Pregnancy Complications | 0.981 | 0.87 – 1.11 | 0.756 | 302 | 3013 | all | phecode |
| 643 | Excessive vomiting in pregnancy | Pregnancy Complications | 0.954 | 0.837 – 1.09 | 0.486 | 252 | 2506 | all | phecode |
| 643.1 | Hyperemesis gravidarum | Pregnancy Complications | 1.02 | 0.84 – 1.23 | 0.862 | 119 | 1190 | all | phecode |
| 644 | Anemia during pregnancy | Pregnancy Complications | 0.955 | 0.833 – 1.09 | 0.508 | 224 | 2224 | all | phecode |
| 646 | Other complications of pregnancy NEC | Pregnancy Complications | 1.02 | 0.949 – 1.1 | 0.584 | 855 | 6531 | all | phecode |
| 647 |
Infectious and parasitic complicationsInfectious and parasitic complications affecting pregnancy
|
Pregnancy Complications | 1.06 | 0.918 – 1.22 | 0.442 | 211 | 2093 | all | phecode |
| 647.1 |
Infections of genitourinary tract duringInfections of genitourinary tract during pregnancy
|
Pregnancy Complications | 1.08 | 0.941 – 1.24 | 0.269 | 222 | 2213 | all | phecode |
| 647.3 | Major puerperal infection | Pregnancy Complications | 1.11 | 0.855 – 1.44 | 0.433 | 65 | 650 | all | phecode |
| 649 |
Other conditions or status of the motherOther conditions or status of the mother complicating pregnancy, childbirth, or the puerperium
|
Pregnancy Complications | 0.956 | 0.9 – 1.02 | 0.142 | 1275 | 8010 | all | phecode |
| 649.1 |
Diabetes or abnormal glucose toleranceDiabetes or abnormal glucose tolerance complicating pregnancy
|
Pregnancy Complications | 0.981 | 0.903 – 1.07 | 0.643 | 649 | 5687 | all | phecode |
| 653 |
Problems associated with amniotic cavity andProblems associated with amniotic cavity and membranes
|
Pregnancy Complications | 0.985 | 0.905 – 1.07 | 0.737 | 587 | 5463 | all | phecode |
| 654.1 |
Abnormality of organs and soft tissues ofAbnormality of organs and soft tissues of pelvis complicating pregnancy, childbirth, or the puerperium
|
Pregnancy Complications | 0.956 | 0.828 – 1.1 | 0.536 | 207 | 2055 | all | phecode |
| 654.2 | Rhesus isoimmunization in pregnancy | Pregnancy Complications | 1.03 | 0.894 – 1.19 | 0.665 | 204 | 2040 | all | phecode |
| 655 |
Known or suspected fetal abnormality affectingKnown or suspected fetal abnormality affecting management of mother
|
Pregnancy Complications | 0.953 | 0.903 – 1.01 | 0.0797 | 1624 | 10064 | all | phecode |
| 655.1 | Abnormality in fetal heart rate or rhythm | Pregnancy Complications | 0.941 | 0.864 – 1.02 | 0.157 | 616 | 5533 | all | phecode |
| 656 | Other perinatal conditions of fetus or newborn | Pregnancy Complications | 1.01 | 0.94 – 1.08 | 0.805 | 898 | 7014 | all | phecode |
| 656.2 | Respiratory conditions of fetus and newborn | Pregnancy Complications | 0.873 | 0.669 – 1.14 | 0.314 | 66 | 660 | all | phecode |
| 669 | Complications of labor and delivery NEC | Pregnancy Complications | 0.933 | 0.869 – 1 | 0.0569 | 887 | 6802 | all | phecode |
| 671 |
Venous/cerebrovascular complications embolismVenous/cerebrovascular complications embolism in pregnancy and the puerperium
|
Pregnancy Complications | 0.97 | 0.845 – 1.11 | 0.664 | 236 | 2351 | all | phecode |
| 674 | Other complications of the puerperium NEC | Pregnancy Complications | 1.03 | 0.87 – 1.21 | 0.744 | 158 | 1580 | all | phecode |
| 676 |
Other disorders of the breast associated withOther disorders of the breast associated with childbirth and disorders of lactation
|
Pregnancy Complications | 0.928 | 0.795 – 1.08 | 0.347 | 184 | 1814 | all | phecode |
| 681 | Superficial cellulitis and abscess | Dermatologic | 1.04 | 1.01 – 1.07 | 0.00418 | 6500 | 38394 | all | phecode |
| 681.1 | Cellulitis and abscess of fingers/toes | Dermatologic | 0.991 | 0.933 – 1.05 | 0.761 | 1256 | 11462 | all | phecode |
| 681.2 | Cellulitis and abscess of face/neck | Dermatologic | 1.08 | 1.01 – 1.15 | 0.0234 | 1007 | 9981 | all | phecode |
| 681.3 | Cellulitis and abscess of arm/hand | Dermatologic | 1.05 | 1 – 1.1 | 0.0371 | 2123 | 19952 | all | phecode |
| 681.5 | Cellulitis and abscess of leg, except foot | Dermatologic | 1.05 | 1.01 – 1.1 | 0.0283 | 2252 | 20944 | all | phecode |
| 681.6 | Cellulitis and abscess of foot, toe | Dermatologic | 1.06 | 1.01 – 1.11 | 0.0262 | 1820 | 16893 | all | phecode |
| 681.7 | Cellulitis and abscess of trunk | Dermatologic | 1.08 | 1.02 – 1.14 | 0.0041 | 1572 | 15588 | all | phecode |
| 686 |
Other local infections of skin and subcutaneousOther local infections of skin and subcutaneous tissue
|
Dermatologic | 1.05 | 1.01 – 1.1 | 0.0217 | 2257 | 21750 | all | phecode |
| 686.1 | Carbuncle and furuncle | Dermatologic | 1.08 | 0.992 – 1.18 | 0.0757 | 558 | 5504 | all | phecode |
| 686.2 | Impetigo | Dermatologic | 1.05 | 0.949 – 1.17 | 0.337 | 414 | 4117 | all | phecode |
| 686.3 | Pilonidal cyst | Dermatologic | 1.06 | 0.898 – 1.25 | 0.502 | 160 | 1594 | all | phecode |
| 686.4 | Pyogenic granuloma | Dermatologic | 0.981 | 0.831 – 1.16 | 0.821 | 158 | 1570 | all | phecode |
| 686.5 | Pyoderma | Dermatologic | 0.922 | 0.709 – 1.2 | 0.547 | 63 | 630 | all | phecode |
| 687 | Symptoms affecting skin | Dermatologic | 1.01 | 0.955 – 1.06 | 0.844 | 1690 | 16343 | all | phecode |
| 687.1 | Rash and other nonspecific skin eruption | Dermatologic | 0.98 | 0.954 – 1.01 | 0.142 | 7007 | 34623 | all | phecode |
| 687.3 | Changes in skin texture | Dermatologic | 1.05 | 0.95 – 1.17 | 0.32 | 415 | 4121 | all | phecode |
| 687.4 | Disturbance of skin sensation | Dermatologic | 1.03 | 1 – 1.06 | 0.0524 | 6375 | 34216 | all | phecode |
| 689 | Disorder of skin and subcutaneous tissue NOS | Dermatologic | 0.954 | 0.932 – 0.977 | 9.79e-05 | 9311 | 37335 | all | phecode |
| 690 | Erythematosquamous dermatosis | Dermatologic | 0.951 | 0.923 – 0.981 | 0.00141 | 5184 | 31581 | all | phecode |
| 690.1 | Seborrheic dermatitis | Dermatologic | 0.951 | 0.922 – 0.981 | 0.00131 | 5174 | 31553 | all | phecode |
| 691 | Congenital anomalies of skin | Dermatologic | 0.967 | 0.884 – 1.06 | 0.471 | 541 | 5337 | all | phecode |
| 691.3 | Congenital pigmentary anomalies of skin | Dermatologic | 0.99 | 0.763 – 1.29 | 0.941 | 62 | 613 | all | phecode |
| 694 | Dyschromia and Vitiligo | Dermatologic | 0.929 | 0.884 – 0.975 | 0.00303 | 1861 | 17936 | all | phecode |
| 694.1 | Vitiligo | Dermatologic | 0.967 | 0.812 – 1.15 | 0.711 | 137 | 1347 | all | phecode |
| 694.2 | Other dyschromia | Dermatologic | 0.923 | 0.877 – 0.972 | 0.00237 | 1674 | 16183 | all | phecode |
| 694.3 | Vascular disorders of skin | Dermatologic | 1.03 | 0.819 – 1.3 | 0.8 | 82 | 819 | all | phecode |
| 695 | Erythematous conditions | Dermatologic | 0.962 | 0.931 – 0.995 | 0.0257 | 4120 | 30247 | all | phecode |
| 695.1 | Toxic erythema | Dermatologic | 0.893 | 0.693 – 1.15 | 0.378 | 70 | 688 | all | phecode |
| 695.2 | Bullous dermatoses | Dermatologic | 1.12 | 0.898 – 1.41 | 0.307 | 85 | 805 | all | phecode |
| 695.3 | Rosacea | Dermatologic | 0.919 | 0.874 – 0.966 | 0.000847 | 1816 | 17663 | all | phecode |
| 695.4 | Lupus (localized and systemic) | Dermatologic | 1 | 0.925 – 1.09 | 0.928 | 672 | 6686 | all | phecode |
| 695.41 | Cutaneous lupus erythematosus | Dermatologic | 1.05 | 0.919 – 1.2 | 0.463 | 247 | 2437 | all | phecode |
| 695.42 | Systemic lupus erythematosus | Dermatologic | 1 | 0.924 – 1.09 | 0.911 | 637 | 6337 | all | phecode |
| 695.7 | Prurigo and Lichen | Dermatologic | 1.05 | 0.959 – 1.14 | 0.314 | 605 | 5986 | all | phecode |
| 695.8 | Other specified erythematous conditions | Dermatologic | 0.931 | 0.864 – 1 | 0.0613 | 812 | 7980 | all | phecode |
| 695.81 | Erythema nodosum | Dermatologic | 0.786 | 0.598 – 1.03 | 0.0849 | 55 | 550 | all | phecode |
| 695.9 | Unspecified erythematous condition | Dermatologic | 0.982 | 0.906 – 1.06 | 0.657 | 679 | 6756 | all | phecode |
| 696 | Psoriasis and related disorders | Dermatologic | 1 | 0.945 – 1.06 | 0.998 | 1401 | 13832 | all | phecode |
| 696.3 | Pityriasis | Dermatologic | 0.955 | 0.768 – 1.19 | 0.681 | 92 | 904 | all | phecode |
| 696.4 | Psoriasis | Dermatologic | 1.01 | 0.956 – 1.07 | 0.65 | 1311 | 12976 | all | phecode |
| 696.41 | Psoriasis vulgaris | Dermatologic | 1.01 | 0.953 – 1.08 | 0.681 | 1200 | 11867 | all | phecode |
| 696.42 | Psoriatic arthropathy | Dermatologic | 1.08 | 0.955 – 1.22 | 0.221 | 282 | 2810 | all | phecode |
| 697 | Sarcoidosis | Dermatologic | 1.06 | 0.948 – 1.19 | 0.296 | 333 | 3330 | all | phecode |
| 698 | Pruritus and related conditions | Dermatologic | 0.98 | 0.937 – 1.02 | 0.371 | 2254 | 21889 | all | phecode |
| 700 | Corns and callosities | Dermatologic | 1.01 | 0.957 – 1.08 | 0.627 | 1373 | 10894 | all | phecode |
| 701 |
Other hypertrophic and atrophic conditions ofOther hypertrophic and atrophic conditions of skin
|
Dermatologic | 1 | 0.975 – 1.03 | 0.992 | 7651 | 38050 | all | phecode |
| 701.1 | Keratoderma, acquired | Dermatologic | 1.07 | 0.975 – 1.17 | 0.163 | 567 | 5524 | all | phecode |
| 701.2 | Scar conditions and fibrosis of skin | Dermatologic | 1.02 | 0.979 – 1.07 | 0.291 | 2184 | 21550 | all | phecode |
| 701.3 | Circumscribed scleroderma | Dermatologic | 0.896 | 0.82 – 0.978 | 0.0142 | 571 | 5660 | all | phecode |
| 701.4 | Keloid scar | Dermatologic | 0.976 | 0.894 – 1.07 | 0.587 | 578 | 5716 | all | phecode |
| 701.5 | Abnormal granulation tissue | Dermatologic | 0.983 | 0.886 – 1.09 | 0.74 | 400 | 3982 | all | phecode |
| 702 |
Degenerative skin conditions and otherDegenerative skin conditions and other dermatoses
|
Dermatologic | 0.943 | 0.917 – 0.969 | 3.02e-05 | 6956 | 29525 | all | phecode |
| 702.1 | Actinic keratosis | Dermatologic | 0.936 | 0.904 – 0.968 | 0.000132 | 4171 | 26529 | all | phecode |
| 702.2 | Seborrheic keratosis | Dermatologic | 0.938 | 0.91 – 0.966 | 2.74e-05 | 5480 | 31552 | all | phecode |
| 702.4 | Degenerative skin disorders | Dermatologic | 0.893 | 0.708 – 1.13 | 0.337 | 86 | 832 | all | phecode |
| 703 | Diseases of nail, NOS | Dermatologic | 0.979 | 0.929 – 1.03 | 0.436 | 1650 | 14562 | all | phecode |
| 703.1 | Ingrowing nail | Dermatologic | 0.996 | 0.929 – 1.07 | 0.914 | 920 | 8597 | all | phecode |
| 704 | Diseases of hair and hair follicles | Dermatologic | 0.952 | 0.916 – 0.989 | 0.0107 | 3118 | 29542 | all | phecode |
| 704.1 | Alopecia | Dermatologic | 0.938 | 0.887 – 0.993 | 0.0271 | 1408 | 13871 | all | phecode |
| 704.11 | Alopecia Areata | Dermatologic | 0.902 | 0.718 – 1.13 | 0.376 | 82 | 811 | all | phecode |
| 704.12 | Telogen effluvium | Dermatologic | 1.03 | 0.783 – 1.35 | 0.846 | 63 | 615 | all | phecode |
| 704.2 | Hirsutism | Dermatologic | 1.2 | 1.07 – 1.36 | 0.00281 | 299 | 2946 | all | phecode |
| 704.8 |
Other specified diseases of hair and hairOther specified diseases of hair and hair follicles
|
Dermatologic | 0.98 | 0.932 – 1.03 | 0.433 | 1752 | 17189 | all | phecode |
| 705 | Disorders of sweat glands | Dermatologic | 1.07 | 0.984 – 1.17 | 0.111 | 603 | 6012 | all | phecode |
| 705.1 | Dyshidrosis | Dermatologic | 1.14 | 0.963 – 1.35 | 0.126 | 154 | 1540 | all | phecode |
| 705.3 | Hidradenitis | Dermatologic | 1.16 | 1.02 – 1.33 | 0.0267 | 245 | 2440 | all | phecode |
| 705.8 | Hyperhidrosis | Dermatologic | 1.01 | 0.944 – 1.07 | 0.865 | 1112 | 10986 | all | phecode |
| 706 | Diseases of sebaceous glands | Dermatologic | 0.967 | 0.94 – 0.995 | 0.0199 | 5995 | 39748 | all | phecode |
| 706.1 | Acne | Dermatologic | 0.939 | 0.9 – 0.979 | 0.00295 | 2594 | 22570 | all | phecode |
| 706.2 | Sebaceous cyst | Dermatologic | 0.968 | 0.93 – 1.01 | 0.11 | 2814 | 26819 | all | phecode |
| 706.3 | Seborrhea | Dermatologic | 1.08 | 0.825 – 1.41 | 0.579 | 59 | 582 | all | phecode |
| 706.8 | Other specified diseases of sebaceous glands | Dermatologic | 0.961 | 0.913 – 1.01 | 0.134 | 1684 | 15289 | all | phecode |
| 707 | Chronic ulcer of skin | Dermatologic | 1.08 | 1.04 – 1.13 | 7.75e-05 | 2871 | 26816 | all | phecode |
| 707.1 | Decubitus ulcer | Dermatologic | 1.09 | 1.02 – 1.18 | 0.0171 | 825 | 8119 | all | phecode |
| 707.2 | Chronic ulcer of leg or foot | Dermatologic | 1.06 | 0.994 – 1.13 | 0.074 | 1108 | 9992 | all | phecode |
| 707.3 | Chronic ulcer of unspecified site | Dermatologic | 1.05 | 0.997 – 1.11 | 0.0646 | 1641 | 16172 | all | phecode |
| 709 | Diffuse diseases of connective tissue | Dermatologic | 1.01 | 0.953 – 1.06 | 0.805 | 1477 | 14427 | all | phecode |
| 709.2 | Sicca syndrome | Dermatologic | 0.991 | 0.901 – 1.09 | 0.859 | 505 | 4986 | all | phecode |
| 709.3 | Systemic sclerosis | Dermatologic | 1.06 | 0.918 – 1.22 | 0.428 | 224 | 2209 | all | phecode |
| 709.5 | Dermatomyositis | Dermatologic | 0.978 | 0.79 – 1.21 | 0.84 | 92 | 892 | all | phecode |
| 709.6 |
Other specified diffuse diseases of connectiveOther specified diffuse diseases of connective tissue
|
Dermatologic | 0.99 | 0.794 – 1.23 | 0.926 | 90 | 892 | all | phecode |
| 709.7 | Unspecified diffuse connective tissue disease | Dermatologic | 1.03 | 0.957 – 1.1 | 0.471 | 917 | 9089 | all | phecode |
| 710 |
Osteomyelitis, periostitis, and otherOsteomyelitis, periostitis, and other infections involving bone
|
Musculoskeletal | 1.07 | 1.01 – 1.14 | 0.0211 | 1254 | 12103 | all | phecode |
| 710.1 | Osteomyelitis | Musculoskeletal | 1.06 | 0.996 – 1.12 | 0.0687 | 1203 | 11636 | all | phecode |
| 710.11 | Acute osteomyelitis | Musculoskeletal | 1.11 | 1.02 – 1.21 | 0.021 | 590 | 5708 | all | phecode |
| 710.12 | Chronic osteomyelitis | Musculoskeletal | 1.06 | 0.964 – 1.16 | 0.238 | 531 | 5163 | all | phecode |
| 710.19 | Unspecified osteomyelitis | Musculoskeletal | 1.06 | 0.999 – 1.13 | 0.0546 | 1153 | 11149 | all | phecode |
| 711 | Arthropathy associated with infections | Musculoskeletal | 1.03 | 0.925 – 1.14 | 0.616 | 410 | 4099 | all | phecode |
| 711.1 | Pyogenic arthritis | Musculoskeletal | 1.02 | 0.906 – 1.16 | 0.707 | 290 | 2900 | all | phecode |
| 712 | Infective connective tissue disorders | Musculoskeletal | 1.08 | 0.93 – 1.26 | 0.302 | 178 | 1776 | all | phecode |
| 713 |
Arthropathy associated with other disordersArthropathy associated with other disorders classified elsewhere
|
Musculoskeletal | 1.03 | 0.912 – 1.15 | 0.677 | 314 | 3028 | all | phecode |
| 713.5 |
Arthropathy associated with neurologicalArthropathy associated with neurological disorders
|
Musculoskeletal | 1.05 | 0.902 – 1.22 | 0.538 | 194 | 1824 | all | phecode |
| 714 |
Rheumatoid arthritis and other inflammatoryRheumatoid arthritis and other inflammatory polyarthropathies
|
Musculoskeletal | 1.07 | 1.02 – 1.12 | 0.00303 | 2086 | 18159 | all | phecode |
| 714.1 | Rheumatoid arthritis | Musculoskeletal | 1.08 | 1.03 – 1.14 | 0.00246 | 1670 | 15087 | all | phecode |
| 714.2 | Juvenile rheumatoid arthritis | Musculoskeletal | 1.26 | 1 – 1.58 | 0.0483 | 77 | 767 | all | phecode |
| 715 | Other inflammatory spondylopathies | Musculoskeletal | 1.04 | 0.974 – 1.1 | 0.262 | 1209 | 11967 | all | phecode |
| 715.1 | Sacroiliitis NEC | Musculoskeletal | 1.07 | 0.937 – 1.21 | 0.332 | 262 | 2611 | all | phecode |
| 715.2 | Ankylosing spondylitis | Musculoskeletal | 0.925 | 0.806 – 1.06 | 0.268 | 219 | 2182 | all | phecode |
| 716 | Other arthropathies | Musculoskeletal | 1.04 | 1.02 – 1.06 | 0.00021 | 13482 | 31305 | all | phecode |
| 716.1 | Unspecified polyarthropathy or polyarthritis | Musculoskeletal | 0.925 | 0.797 – 1.07 | 0.306 | 192 | 1920 | all | phecode |
| 716.2 | Unspecified monoarthritis | Musculoskeletal | 0.842 | 0.701 – 1.01 | 0.0667 | 131 | 1293 | all | phecode |
| 716.9 | Arthropathy NOS | Musculoskeletal | 1.04 | 1.02 – 1.06 | 0.000284 | 13410 | 31294 | all | phecode |
| 717 | Polymyalgia Rheumatica | Musculoskeletal | 0.936 | 0.822 – 1.07 | 0.325 | 261 | 2565 | all | phecode |
| 720 | Spinal stenosis | Musculoskeletal | 1.05 | 1.01 – 1.08 | 0.0117 | 3958 | 28539 | all | phecode |
| 720.1 | Spinal stenosis of lumbar region | Musculoskeletal | 1.02 | 0.981 – 1.06 | 0.304 | 2872 | 23656 | all | phecode |
| 721 | Spondylosis and allied disorders | Musculoskeletal | 1.04 | 1.01 – 1.07 | 0.00539 | 5509 | 32391 | all | phecode |
| 721.1 | Spondylosis without myelopathy | Musculoskeletal | 1.04 | 1.01 – 1.07 | 0.0193 | 5153 | 31896 | all | phecode |
| 721.2 | Spondylosis with myelopathy | Musculoskeletal | 1.07 | 0.991 – 1.14 | 0.0857 | 867 | 8629 | all | phecode |
| 721.8 | Other allied disorders of spine | Musculoskeletal | 1.12 | 0.986 – 1.27 | 0.0821 | 262 | 2600 | all | phecode |
| 722 | Intervertebral disc disorders | Musculoskeletal | 1.06 | 1.03 – 1.09 | 4.16e-05 | 6284 | 34317 | all | phecode |
| 722.1 | Displacement of intervertebral disc | Musculoskeletal | 1.04 | 1 – 1.08 | 0.0333 | 3591 | 31411 | all | phecode |
| 722.3 | Schmorl's nodes | Musculoskeletal | 1.12 | 0.924 – 1.35 | 0.254 | 126 | 1248 | all | phecode |
| 722.6 | Degeneration of intervertebral disc | Musculoskeletal | 1.07 | 1.03 – 1.1 | 0.000292 | 3957 | 30744 | all | phecode |
| 722.7 | Intervertebral disc disorder with myelopathy | Musculoskeletal | 1.09 | 0.995 – 1.2 | 0.0637 | 515 | 5140 | all | phecode |
| 722.8 | Postlaminectomy syndrome | Musculoskeletal | 1.1 | 0.993 – 1.23 | 0.0668 | 397 | 3968 | all | phecode |
| 722.9 | Other and unspecified disc disorder | Musculoskeletal | 1.1 | 1.05 – 1.16 | 6.18e-05 | 1932 | 19288 | all | phecode |
| 723 | Other disorders of cervical region | Musculoskeletal | 1.01 | 0.943 – 1.08 | 0.782 | 952 | 9495 | all | phecode |
| 723.1 | Torticollis | Musculoskeletal | 1.02 | 0.889 – 1.16 | 0.824 | 254 | 2522 | all | phecode |
| 724 | Other and unspecified disorders of back | Musculoskeletal | 1.03 | 0.992 – 1.06 | 0.138 | 4130 | 31954 | all | phecode |
| 724.1 | Disorders of sacrum | Musculoskeletal | 1.04 | 0.994 – 1.09 | 0.0872 | 2307 | 21902 | all | phecode |
| 724.2 | Disorders of coccyx | Musculoskeletal | 0.92 | 0.832 – 1.02 | 0.106 | 426 | 4215 | all | phecode |
| 724.8 | Other symptoms referable to back | Musculoskeletal | 1.06 | 0.991 – 1.14 | 0.0874 | 931 | 9295 | all | phecode |
| 724.9 | Other unspecified back disorders | Musculoskeletal | 1.04 | 0.98 – 1.1 | 0.212 | 1412 | 14087 | all | phecode |
| 726 | Peripheral enthesopathies and allied syndromes | Musculoskeletal | 0.987 | 0.964 – 1.01 | 0.27 | 9917 | 30176 | all | phecode |
| 726.1 | Enthesopathy | Musculoskeletal | 0.983 | 0.958 – 1.01 | 0.207 | 7507 | 30106 | all | phecode |
| 726.2 | Synoviopathy | Musculoskeletal | 0.983 | 0.92 – 1.05 | 0.621 | 1015 | 9987 | all | phecode |
| 726.3 | Bursitis | Musculoskeletal | 0.993 | 0.945 – 1.04 | 0.783 | 1829 | 16722 | all | phecode |
| 726.4 | Calcaneal spur; Exostosis NOS | Musculoskeletal | 0.975 | 0.917 – 1.04 | 0.417 | 1193 | 11485 | all | phecode |
| 727 | Other disorders of synovium, tendon, and bursa | Musculoskeletal | 1 | 0.977 – 1.03 | 0.842 | 7425 | 30105 | all | phecode |
| 727.1 | Synovitis and tenosynovitis | Musculoskeletal | 1 | 0.962 – 1.04 | 0.981 | 3092 | 24998 | all | phecode |
| 727.2 | Bursitis disorders | Musculoskeletal | 1.05 | 0.945 – 1.16 | 0.377 | 419 | 4112 | all | phecode |
| 727.4 | Ganglion and cyst of synovium, tendon, and bursa | Musculoskeletal | 0.942 | 0.891 – 0.997 | 0.0391 | 1400 | 13621 | all | phecode |
| 727.5 | Rupture of synovium | Musculoskeletal | 0.971 | 0.882 – 1.07 | 0.544 | 480 | 4672 | all | phecode |
| 727.6 | Rupture of tendon, nontraumatic | Musculoskeletal | 1.01 | 0.967 – 1.05 | 0.682 | 2461 | 21948 | all | phecode |
| 727.7 | Contracture of tendon (sheath) | Musculoskeletal | 1.08 | 0.995 – 1.18 | 0.0666 | 591 | 5893 | all | phecode |
| 727.8 | Plica syndrome | Musculoskeletal | 1.11 | 0.918 – 1.34 | 0.284 | 130 | 1264 | all | phecode |
| 728 | Disorders of muscle, ligament, and fascia | Musculoskeletal | 1.01 | 0.977 – 1.04 | 0.585 | 4546 | 29473 | all | phecode |
| 728.1 | Muscular calcification and ossification | Musculoskeletal | 1.15 | 0.916 – 1.43 | 0.231 | 85 | 843 | all | phecode |
| 728.2 | Laxity of ligament or hypermobility syndrome | Musculoskeletal | 0.975 | 0.863 – 1.1 | 0.685 | 297 | 2949 | all | phecode |
| 728.7 | Fasciitis | Musculoskeletal | 0.953 | 0.915 – 0.992 | 0.0198 | 2814 | 23463 | all | phecode |
| 728.71 |
Contracture of palmar fascia [Dupuytren'sContracture of palmar fascia [Dupuytren's disease]
|
Musculoskeletal | 0.97 | 0.876 – 1.07 | 0.555 | 419 | 4138 | all | phecode |
| 729 | Other disorders of soft tissues | Musculoskeletal | 1.02 | 0.981 – 1.05 | 0.365 | 3642 | 27471 | all | phecode |
| 729.1 | Rheumatism, unspecified and fibrositis | Musculoskeletal | 1.06 | 0.832 – 1.35 | 0.643 | 74 | 726 | all | phecode |
| 729.3 | Panniculitis | Musculoskeletal | 1.02 | 0.844 – 1.24 | 0.817 | 119 | 1174 | all | phecode |
| 729.7 | Nontraumatic compartment syndrome | Musculoskeletal | 0.955 | 0.739 – 1.23 | 0.723 | 67 | 664 | all | phecode |
| 731 |
Osteitis deformans and osteopathies associatedOsteitis deformans and osteopathies associated with other disorders classified elsewhere
|
Musculoskeletal | 1.1 | 0.951 – 1.28 | 0.196 | 210 | 2091 | all | phecode |
| 732 | Osteochondropathies | Musculoskeletal | 1.01 | 0.903 – 1.13 | 0.883 | 361 | 3604 | all | phecode |
| 732.1 | Juvenile osteochondrosis | Musculoskeletal | 1.06 | 0.916 – 1.22 | 0.44 | 198 | 1969 | all | phecode |
| 732.7 | Osteochondritis dissecans | Musculoskeletal | 0.852 | 0.687 – 1.06 | 0.148 | 90 | 882 | all | phecode |
| 733 | Other disorders of bone and cartilage | Musculoskeletal | 0.951 | 0.92 – 0.982 | 0.00264 | 4543 | 26941 | all | phecode |
| 733.2 | Cyst of bone | Musculoskeletal | 0.902 | 0.774 – 1.05 | 0.188 | 190 | 1900 | all | phecode |
| 733.4 | Aseptic necrosis of bone | Musculoskeletal | 1.05 | 0.955 – 1.15 | 0.323 | 518 | 5160 | all | phecode |
| 733.6 | Costochondritis | Musculoskeletal | 0.972 | 0.869 – 1.09 | 0.619 | 357 | 3562 | all | phecode |
| 733.8 | Malunion and nonunion of fracture | Musculoskeletal | 0.996 | 0.927 – 1.07 | 0.923 | 822 | 8205 | all | phecode |
| 733.9 | Chondromalacia | Musculoskeletal | 1.18 | 0.954 – 1.46 | 0.127 | 96 | 960 | all | phecode |
| 735 | Acquired foot deformities | Musculoskeletal | 1.01 | 0.97 – 1.04 | 0.76 | 3417 | 29622 | all | phecode |
| 735.1 | Flat foot | Musculoskeletal | 0.992 | 0.911 – 1.08 | 0.846 | 620 | 6092 | all | phecode |
| 735.2 | Acquired toe deformities | Musculoskeletal | 1.01 | 0.954 – 1.07 | 0.698 | 1323 | 11983 | all | phecode |
| 735.21 | Hammer toe (acquired) | Musculoskeletal | 1.05 | 0.979 – 1.14 | 0.162 | 825 | 7494 | all | phecode |
| 735.23 | Hallux rigidus | Musculoskeletal | 0.952 | 0.857 – 1.06 | 0.367 | 405 | 4005 | all | phecode |
| 735.3 | Hallux valgus (Bunion) | Musculoskeletal | 0.988 | 0.935 – 1.04 | 0.663 | 1470 | 14295 | all | phecode |
| 736 | Other acquired deformities of limbs | Musculoskeletal | 1.01 | 0.975 – 1.06 | 0.474 | 2763 | 26555 | all | phecode |
| 736.1 | Acquired deformities of forearm | Musculoskeletal | 1.17 | 0.955 – 1.44 | 0.13 | 104 | 1033 | all | phecode |
| 736.2 | Acquired deformities of finger | Musculoskeletal | 0.954 | 0.828 – 1.1 | 0.514 | 215 | 2142 | all | phecode |
| 736.3 | Acquired deformities of hip | Musculoskeletal | 0.975 | 0.746 – 1.27 | 0.854 | 60 | 590 | all | phecode |
| 736.4 | Genu valgum or varum (acquired) | Musculoskeletal | 0.95 | 0.844 – 1.07 | 0.398 | 325 | 3247 | all | phecode |
| 736.5 | Acquired deformities of knee | Musculoskeletal | 0.904 | 0.789 – 1.04 | 0.148 | 246 | 2460 | all | phecode |
| 736.6 | Unequal leg length (acquired) | Musculoskeletal | 1.02 | 0.91 – 1.14 | 0.765 | 339 | 3365 | all | phecode |
| 737 | Curvature of spine | Musculoskeletal | 0.954 | 0.905 – 1.01 | 0.0836 | 1566 | 15543 | all | phecode |
| 737.1 | Kyphosis (acquired) | Musculoskeletal | 0.952 | 0.866 – 1.05 | 0.315 | 479 | 4748 | all | phecode |
| 737.2 | Lordosis (acquired) | Musculoskeletal | 1.23 | 0.956 – 1.57 | 0.109 | 70 | 700 | all | phecode |
| 737.3 | Kyphoscoliosis and scoliosis | Musculoskeletal | 0.968 | 0.912 – 1.03 | 0.299 | 1203 | 11982 | all | phecode |
| 738 | Other acquired musculoskeletal deformity | Musculoskeletal | 1.03 | 0.986 – 1.07 | 0.188 | 2443 | 24187 | all | phecode |
| 738.4 | Acquired spondylolisthesis | Musculoskeletal | 1.05 | 0.981 – 1.12 | 0.164 | 1057 | 10542 | all | phecode |
| 739 | Contracture of joint | Musculoskeletal | 0.933 | 0.857 – 1.01 | 0.104 | 621 | 6207 | all | phecode |
| 740 | Osteoarthrosis | Musculoskeletal | 1.04 | 1.02 – 1.06 | 0.000355 | 16169 | 30268 | all | phecode |
| 740.1 | Osteoarthritis; localized | Musculoskeletal | 1.02 | 0.988 – 1.05 | 0.255 | 7005 | 27422 | all | phecode |
| 740.11 | Osteoarthrosis, localized, primary | Musculoskeletal | 1.01 | 0.982 – 1.04 | 0.443 | 6176 | 26155 | all | phecode |
| 740.12 | Osteoarthrosis, localized, secondary | Musculoskeletal | 1.07 | 0.991 – 1.16 | 0.0833 | 713 | 7116 | all | phecode |
| 740.2 | Osteoarthrosis, generalized | Musculoskeletal | 0.989 | 0.936 – 1.04 | 0.677 | 1609 | 12092 | all | phecode |
| 740.3 |
Osteoarthrosis involving more than one siteOsteoarthrosis involving more than one site, but not specified as generalized
|
Musculoskeletal | 1.04 | 0.933 – 1.16 | 0.464 | 373 | 3586 | all | phecode |
| 740.9 | Osteoarthrosis NOS | Musculoskeletal | 1.04 | 1.02 – 1.06 | 0.000326 | 15497 | 30141 | all | phecode |
| 741 | Symptoms and disorders of the joints | Musculoskeletal | 0.996 | 0.972 – 1.02 | 0.723 | 8555 | 35884 | all | phecode |
| 741.1 | Ankylosis of joint | Musculoskeletal | 1.05 | 0.917 – 1.2 | 0.485 | 245 | 2445 | all | phecode |
| 741.2 | Stiffness of joint | Musculoskeletal | 0.947 | 0.892 – 1 | 0.071 | 1268 | 12594 | all | phecode |
| 741.3 | Difficulty in walking | Musculoskeletal | 1.02 | 0.974 – 1.06 | 0.458 | 2558 | 23116 | all | phecode |
| 741.4 | Joint effusions | Musculoskeletal | 1 | 0.963 – 1.05 | 0.818 | 2493 | 24199 | all | phecode |
| 741.5 | Hemarthrosis | Musculoskeletal | 0.962 | 0.771 – 1.2 | 0.728 | 94 | 937 | all | phecode |
| 741.6 | Villonodular synovitis | Musculoskeletal | 0.923 | 0.718 – 1.19 | 0.532 | 68 | 666 | all | phecode |
| 742 | Derangement of joint, non-traumatic | Musculoskeletal | 1.03 | 1 – 1.07 | 0.0376 | 4404 | 33771 | all | phecode |
| 742.1 | Loose body in joint | Musculoskeletal | 1.09 | 0.926 – 1.29 | 0.298 | 156 | 1554 | all | phecode |
| 742.2 |
Pathological, developmental or recurrentPathological, developmental or recurrent dislocation
|
Musculoskeletal | 0.997 | 0.881 – 1.13 | 0.967 | 280 | 2792 | all | phecode |
| 742.8 | Articular cartilage disorder | Musculoskeletal | 1.01 | 0.881 – 1.15 | 0.907 | 245 | 2450 | all | phecode |
| 742.9 | Other derangement of joint | Musculoskeletal | 1.03 | 1 – 1.07 | 0.0507 | 4107 | 32972 | all | phecode |
| 743 |
Osteoporosis, osteopenia and pathologicalOsteoporosis, osteopenia and pathological fracture
|
Musculoskeletal | 0.977 | 0.953 – 1 | 0.0592 | 9223 | 36921 | all | phecode |
| 743.1 | Osteoporosis | Musculoskeletal | 0.981 | 0.944 – 1.02 | 0.313 | 3712 | 19477 | all | phecode |
| 743.11 | Osteoporosis NOS | Musculoskeletal | 0.983 | 0.946 – 1.02 | 0.372 | 3657 | 19276 | all | phecode |
| 743.12 | Senile osteoporosis | Musculoskeletal | 0.953 | 0.878 – 1.03 | 0.255 | 703 | 5804 | all | phecode |
| 743.13 | Other specified osteoporosis | Musculoskeletal | 0.954 | 0.846 – 1.07 | 0.436 | 321 | 3141 | all | phecode |
| 743.2 | Pathologic fracture | Musculoskeletal | 0.964 | 0.905 – 1.03 | 0.26 | 1112 | 10563 | all | phecode |
| 743.21 | Pathologic fracture of vertebrae | Musculoskeletal | 0.992 | 0.901 – 1.09 | 0.876 | 475 | 4629 | all | phecode |
| 743.22 | Pathologic fracture of femur | Musculoskeletal | 0.935 | 0.783 – 1.12 | 0.456 | 143 | 1391 | all | phecode |
| 743.4 | Stress fracture | Musculoskeletal | 0.929 | 0.836 – 1.03 | 0.167 | 407 | 4046 | all | phecode |
| 743.9 |
Osteopenia or other disorder of bone andOsteopenia or other disorder of bone and cartilage
|
Musculoskeletal | 0.967 | 0.941 – 0.993 | 0.0142 | 6970 | 35237 | all | phecode |
| 745 | Pain in joint | Musculoskeletal | 0.986 | 0.967 – 1 | 0.142 | 19848 | 26918 | all | phecode |
| 747 | Cardiac and circulatory congenital anomalies | Congenital Anomalies | 1.03 | 0.986 – 1.08 | 0.186 | 2236 | 22256 | all | phecode |
| 747.1 | Cardiac congenital anomalies | Congenital Anomalies | 1.02 | 0.972 – 1.07 | 0.399 | 1767 | 17598 | all | phecode |
| 747.11 | Cardiac shunt/ heart septal defect | Congenital Anomalies | 1.02 | 0.937 – 1.11 | 0.669 | 650 | 6497 | all | phecode |
| 747.12 | Valvular heart disease/ heart chambers | Congenital Anomalies | 1.02 | 0.946 – 1.1 | 0.579 | 751 | 7480 | all | phecode |
| 747.13 | Congenital anomalies of great vessels | Congenital Anomalies | 1.02 | 0.917 – 1.13 | 0.763 | 410 | 4090 | all | phecode |
| 747.2 |
Congenital anomalies of peripheral vascularCongenital anomalies of peripheral vascular system
|
Congenital Anomalies | 1.02 | 0.927 – 1.12 | 0.713 | 501 | 5010 | all | phecode |
| 748 | Anomalies of respiratory system, congenital | Congenital Anomalies | 1.13 | 0.927 – 1.38 | 0.223 | 111 | 1110 | all | phecode |
| 749 | Congenital anomalies of face and neck | Congenital Anomalies | 0.974 | 0.891 – 1.06 | 0.561 | 555 | 5549 | all | phecode |
| 749.1 | Cleft palate | Congenital Anomalies | 0.869 | 0.706 – 1.07 | 0.184 | 97 | 970 | all | phecode |
| 749.2 | Congenital anomalies of skull and face bones | Congenital Anomalies | 0.924 | 0.758 – 1.13 | 0.437 | 105 | 1041 | all | phecode |
| 750 | Digestive congenital anomalies | Congenital Anomalies | 1.01 | 0.937 – 1.08 | 0.88 | 893 | 8919 | all | phecode |
| 750.1 | Upper gastrointestinal congenital anomalies | Congenital Anomalies | 1.02 | 0.911 – 1.13 | 0.765 | 366 | 3655 | all | phecode |
| 750.11 | Esophageal atresia/tracheoesophageal fistula | Congenital Anomalies | 0.877 | 0.722 – 1.07 | 0.187 | 119 | 1185 | all | phecode |
| 750.13 | Congenital anomalies of mouth/tongue | Congenital Anomalies | 0.915 | 0.741 – 1.13 | 0.406 | 99 | 982 | all | phecode |
| 750.14 | Congenital anomalies of esophagus | Congenital Anomalies | 0.915 | 0.758 – 1.11 | 0.358 | 134 | 1332 | all | phecode |
| 750.15 | Congenital anomalies of stomach | Congenital Anomalies | 1.21 | 0.924 – 1.57 | 0.168 | 60 | 593 | all | phecode |
| 750.2 | Lower gastrointestinal congenital anomalies | Congenital Anomalies | 1 | 0.916 – 1.1 | 0.919 | 531 | 5300 | all | phecode |
| 750.21 | Congenital anomalies of intestine | Congenital Anomalies | 1.04 | 0.919 – 1.17 | 0.564 | 313 | 3129 | all | phecode |
| 750.22 |
Congenital anomaly of gallbladder, bile ductsCongenital anomaly of gallbladder, bile ducts, liver, pancreas
|
Congenital Anomalies | 0.984 | 0.857 – 1.13 | 0.823 | 222 | 2214 | all | phecode |
| 751 | Genitourinary congenital anomalies | Congenital Anomalies | 1.01 | 0.964 – 1.06 | 0.656 | 2008 | 19975 | all | phecode |
| 751.1 | Congenital anomalies of genital organs | Congenital Anomalies | 1.02 | 0.938 – 1.12 | 0.605 | 574 | 5740 | all | phecode |
| 751.11 | Congenital anomalies of female genital organs | Congenital Anomalies | 1.04 | 0.938 – 1.16 | 0.425 | 384 | 3840 | all | phecode |
| 751.12 | Congenital anomalies of male genital organs | Congenital Anomalies | 0.981 | 0.829 – 1.16 | 0.818 | 153 | 1527 | all | phecode |
| 751.2 | Congenital anomalies of urinary system | Congenital Anomalies | 0.992 | 0.938 – 1.05 | 0.787 | 1379 | 13704 | all | phecode |
| 751.21 | Cystic kidney disease | Congenital Anomalies | 0.958 | 0.896 – 1.03 | 0.215 | 976 | 9685 | all | phecode |
| 751.22 | Other specified congenital anomalies of kidney | Congenital Anomalies | 1.03 | 0.916 – 1.17 | 0.581 | 294 | 2927 | all | phecode |
| 751.3 | Obstructive genitourinary defect | Congenital Anomalies | 1.13 | 0.968 – 1.32 | 0.124 | 182 | 1809 | all | phecode |
| 752 | Nervous system congenital anomalies | Congenital Anomalies | 1.01 | 0.946 – 1.07 | 0.838 | 1133 | 11313 | all | phecode |
| 752.1 | Neural tube defects | Congenital Anomalies | 1 | 0.937 – 1.08 | 0.917 | 923 | 9209 | all | phecode |
| 752.11 | Spina bifida | Congenital Anomalies | 0.926 | 0.788 – 1.09 | 0.351 | 176 | 1760 | all | phecode |
| 752.2 |
Other specified congenital anomalies of nervousOther specified congenital anomalies of nervous system
|
Congenital Anomalies | 0.952 | 0.829 – 1.09 | 0.484 | 232 | 2320 | all | phecode |
| 753 | Congenital anomalies of the eye | Congenital Anomalies | 0.846 | 0.732 – 0.977 | 0.023 | 207 | 2051 | all | phecode |
| 753.1 | Congenital cataract and lens anomalies | Congenital Anomalies | 0.829 | 0.632 – 1.09 | 0.175 | 58 | 580 | all | phecode |
| 753.2 | Congenital anomalies of posterior segment of eye | Congenital Anomalies | 0.914 | 0.702 – 1.19 | 0.505 | 56 | 546 | all | phecode |
| 754 | Congenital musculoskeletal deformities of spine | Congenital Anomalies | 1.05 | 0.986 – 1.11 | 0.134 | 1216 | 12116 | all | phecode |
| 754.1 | Lumbosacral spondylolysis, congenital | Congenital Anomalies | 1.12 | 0.943 – 1.34 | 0.192 | 135 | 1333 | all | phecode |
| 754.2 | Spondylolisthesis, congenital | Congenital Anomalies | 1.02 | 0.937 – 1.12 | 0.601 | 558 | 5570 | all | phecode |
| 755 | Congenital anomalies of limbs | Congenital Anomalies | 0.997 | 0.923 – 1.08 | 0.949 | 747 | 7458 | all | phecode |
| 755.1 | Congenital deformities of feet | Congenital Anomalies | 0.934 | 0.838 – 1.04 | 0.221 | 368 | 3663 | all | phecode |
| 755.4 |
Congenital anomalies of upper limb, includingCongenital anomalies of upper limb, including shoulder girdle
|
Congenital Anomalies | 1.39 | 1.08 – 1.78 | 0.0102 | 74 | 740 | all | phecode |
| 755.6 |
Other congenital anomalies of lower limbOther congenital anomalies of lower limb, including pelvic girdle
|
Congenital Anomalies | 1.05 | 0.933 – 1.18 | 0.422 | 321 | 3205 | all | phecode |
| 755.61 | Congenital hip dysplasia and deformity | Congenital Anomalies | 1 | 0.856 – 1.17 | 0.992 | 185 | 1847 | all | phecode |
| 756 | Other congenital musculoskeletal anomalies | Congenital Anomalies | 1 | 0.948 – 1.06 | 0.893 | 1358 | 13579 | all | phecode |
| 756.1 | Congenital anomalies of abdominal wall; diaphram | Congenital Anomalies | 0.861 | 0.667 – 1.11 | 0.25 | 68 | 680 | all | phecode |
| 756.2 |
Pectus and other congenital anomalies ofPectus and other congenital anomalies of ribs/sternum
|
Congenital Anomalies | 0.771 | 0.6 – 0.993 | 0.0436 | 71 | 694 | all | phecode |
| 756.3 |
Congenital anomalies of muscle, tendon, fasciaCongenital anomalies of muscle, tendon, fascia, and connective tissue
|
Congenital Anomalies | 0.938 | 0.836 – 1.05 | 0.276 | 335 | 3346 | all | phecode |
| 756.5 | Congenital osteodystrophies | Congenital Anomalies | 1.04 | 0.969 – 1.11 | 0.299 | 1003 | 10014 | all | phecode |
| 757 | Congenital anomalies of the integument | Congenital Anomalies | 0.983 | 0.885 – 1.09 | 0.752 | 401 | 4001 | all | phecode |
| 758 | Chromosomal anomalies and genetic disorders | Congenital Anomalies | 0.952 | 0.816 – 1.11 | 0.533 | 185 | 1845 | all | phecode |
| 758.1 | Chromosomal anomalies | Congenital Anomalies | 0.947 | 0.792 – 1.13 | 0.552 | 135 | 1349 | all | phecode |
| 759 | Other and unspecified congenital anomalies | Congenital Anomalies | 1 | 0.919 – 1.09 | 0.95 | 557 | 5566 | all | phecode |
| 759.1 | Anomalies of endocrine glands, congenital | Congenital Anomalies | 0.967 | 0.762 – 1.23 | 0.785 | 71 | 710 | all | phecode |
| 760 | Back pain | Symptoms | 1.04 | 1.02 – 1.07 | 1.66e-05 | 16037 | 30719 | all | phecode |
| 761 | Cervicalgia | Symptoms | 1.05 | 1.02 – 1.08 | 0.000734 | 6528 | 39755 | all | phecode |
| 763 |
Thoracic or lumbosacral neuritis orThoracic or lumbosacral neuritis or radiculitis, unspecified
|
Symptoms | 1.04 | 1 – 1.08 | 0.0275 | 3657 | 32599 | all | phecode |
| 764 | Sciatica | Symptoms | 1.04 | 0.999 – 1.07 | 0.0585 | 3542 | 32015 | all | phecode |
| 765 | Cervical radiculitis | Symptoms | 1.06 | 1.01 – 1.12 | 0.02 | 1799 | 17851 | all | phecode |
| 766 | Neuralgia, neuritis, and radiculitis NOS | Symptoms | 1.05 | 1.02 – 1.08 | 0.00111 | 5124 | 37132 | all | phecode |
| 767 | Cervicocranial/Cervicobrachial syndrome | Symptoms | 1.02 | 0.843 – 1.24 | 0.825 | 117 | 1168 | all | phecode |
| 769 | Nonallopathic lesions NEC | Symptoms | 1 | 0.942 – 1.07 | 0.916 | 1131 | 11220 | all | phecode |
| 770 | Myalgia and myositis unspecified | Symptoms | 1.03 | 1 – 1.06 | 0.0253 | 5533 | 34303 | all | phecode |
| 771 | Musculoskeletal symptoms referable to limbs | Symptoms | 1.01 | 0.981 – 1.04 | 0.469 | 4799 | 35575 | all | phecode |
| 771.1 | Swelling of limb | Symptoms | 1.03 | 1 – 1.06 | 0.0301 | 5743 | 35539 | all | phecode |
| 771.2 | Cramp of limb | Symptoms | 1 | 0.941 – 1.07 | 0.911 | 1079 | 10568 | all | phecode |
| 772 | Symptoms of the muscles | Symptoms | 0.972 | 0.928 – 1.02 | 0.228 | 2042 | 20221 | all | phecode |
| 772.1 | Muscular wasting and disuse atrophy | Symptoms | 1.09 | 0.981 – 1.2 | 0.112 | 422 | 4199 | all | phecode |
| 772.2 | Spasm of muscle | Symptoms | 0.995 | 0.952 – 1.04 | 0.817 | 2299 | 22726 | all | phecode |
| 772.3 | Muscle weakness | Symptoms | 1.04 | 1 – 1.08 | 0.0421 | 2949 | 28064 | all | phecode |
| 772.4 | Rhabdomyolysis | Symptoms | 1.14 | 0.962 – 1.34 | 0.132 | 159 | 1572 | all | phecode |
| 772.6 | Facial weakness | Symptoms | 0.964 | 0.877 – 1.06 | 0.449 | 478 | 4742 | all | phecode |
| 780 | Hypothermia/Chills | Symptoms | 0.99 | 0.897 – 1.09 | 0.843 | 453 | 4514 | all | phecode |
| 781 |
Symptoms involving nervous and musculoskeletalSymptoms involving nervous and musculoskeletal systems
|
Symptoms | 1.02 | 0.983 – 1.06 | 0.259 | 2822 | 26225 | all | phecode |
| 781.1 | Loss of height | Symptoms | 0.87 | 0.722 – 1.05 | 0.146 | 130 | 1269 | all | phecode |
| 781.2 | Abnormal posture | Symptoms | 1.09 | 0.826 – 1.45 | 0.529 | 57 | 567 | all | phecode |
| 782.3 | Edema | Symptoms | 1.04 | 1.01 – 1.07 | 0.0159 | 5874 | 36788 | all | phecode |
| 782.6 | Pallor and flushing | Symptoms | 0.968 | 0.903 – 1.04 | 0.361 | 927 | 9252 | all | phecode |
| 783 | Fever of unknown origin | Symptoms | 1.01 | 0.984 – 1.04 | 0.397 | 5733 | 40720 | all | phecode |
| 783.1 | Postprocedural fever | Symptoms | 1.07 | 0.947 – 1.2 | 0.286 | 300 | 2992 | all | phecode |
| 785 | Abdominal pain | Symptoms | 1.05 | 1.03 – 1.07 | 7.55e-06 | 16458 | 30297 | all | phecode |
| 788 | Syncope and collapse | Symptoms | 0.997 | 0.964 – 1.03 | 0.877 | 3851 | 35832 | all | phecode |
| 789 | Nausea and vomiting | Symptoms | 1.02 | 1 – 1.05 | 0.032 | 10568 | 36098 | all | phecode |
| 789.1 | Persistent vomiting | Symptoms | 1.06 | 0.982 – 1.14 | 0.137 | 798 | 7924 | all | phecode |
| 790 | Nonspecific findings on examination of blood | Symptoms | 0.998 | 0.956 – 1.04 | 0.94 | 2363 | 22690 | all | phecode |
| 790.1 | Elevated sedimentation rate | Symptoms | 1.11 | 0.966 – 1.27 | 0.143 | 236 | 2322 | all | phecode |
| 790.6 | Other abnormal blood chemistry | Symptoms | 1 | 0.976 – 1.03 | 0.921 | 7539 | 37788 | all | phecode |
| 790.8 | Elevated C-reactive protein (CRP) | Symptoms | 1.18 | 1.05 – 1.33 | 0.00648 | 309 | 3075 | all | phecode |
| 790.9 | Abnormal arterial blood gases | Symptoms | 1.12 | 0.947 – 1.32 | 0.185 | 155 | 1521 | all | phecode |
| 791 | Gangrene | Symptoms | 1.16 | 1.03 – 1.3 | 0.0159 | 313 | 3115 | all | phecode |
| 792 |
Abnormal Papanicolaou smear of cervix andAbnormal Papanicolaou smear of cervix and cervical HPV
|
Genitourinary | 1.01 | 0.972 – 1.06 | 0.547 | 2820 | 14872 | all | phecode |
| 792.1 |
Papanicolaou smear of cervix or vagina withPapanicolaou smear of cervix or vagina with atypical squamous cells
|
Genitourinary | 1.03 | 0.965 – 1.1 | 0.381 | 1100 | 9861 | all | phecode |
| 794 |
Abnormal results of other function studiesAbnormal results of other function studies (bladder, pancreas, placenta, spleen, etc)
|
Symptoms | 0.92 | 0.839 – 1.01 | 0.0772 | 515 | 5133 | all | phecode |
| 795 |
Other and nonspecific abnormal cytologicalOther and nonspecific abnormal cytological, histological and immunological findings
|
Symptoms | 0.997 | 0.953 – 1.04 | 0.908 | 2182 | 20242 | all | phecode |
| 795.8 | Abnormal tumor markers | Symptoms | 0.943 | 0.896 – 0.992 | 0.0221 | 1745 | 15551 | all | phecode |
| 795.81 | Elevated carcinoembryonic antigen [CEA] | Symptoms | 0.922 | 0.708 – 1.2 | 0.545 | 61 | 605 | all | phecode |
| 795.82 | Elevated cancer antigen 125 [CA 125] | Symptoms | 0.944 | 0.816 – 1.09 | 0.438 | 201 | 2000 | all | phecode |
| 796 | Elevated prostate specific antigen [PSA] | Genitourinary | 0.919 | 0.875 – 0.965 | 0.000696 | 2125 | 9930 | all | phecode |
| 797 | Shock | Symptoms | 1.07 | 0.987 – 1.17 | 0.099 | 605 | 6050 | all | phecode |
| 797.1 | Cardiogenic shock | Symptoms | 1.05 | 0.917 – 1.2 | 0.483 | 242 | 2420 | all | phecode |
| 798 | Malaise and fatigue | Symptoms | 1 | 0.983 – 1.03 | 0.694 | 11539 | 35196 | all | phecode |
| 798.1 | Chronic fatigue syndrome | Symptoms | 1.03 | 0.983 – 1.08 | 0.201 | 1823 | 17795 | all | phecode |
| 800 | Fracture of lower limb | Injuries & Poisonings | 1.01 | 0.966 – 1.05 | 0.673 | 2344 | 22951 | all | phecode |
| 800.1 | Fracture of neck of femur | Injuries & Poisonings | 1.01 | 0.919 – 1.11 | 0.855 | 512 | 4961 | all | phecode |
| 800.2 | Fracture of unspecified part of femur | Injuries & Poisonings | 1.02 | 0.94 – 1.11 | 0.63 | 670 | 6582 | all | phecode |
| 800.3 | Fracture of tibia and fibula | Injuries & Poisonings | 0.965 | 0.9 – 1.04 | 0.328 | 898 | 8966 | all | phecode |
| 800.4 | Fracture of patella | Injuries & Poisonings | 1.06 | 0.946 – 1.19 | 0.316 | 346 | 3456 | all | phecode |
| 801 | Fracture of ankle and foot | Injuries & Poisonings | 1 | 0.957 – 1.04 | 0.987 | 2358 | 22645 | all | phecode |
| 801.1 | Fracture of foot | Injuries & Poisonings | 0.993 | 0.932 – 1.06 | 0.833 | 1120 | 11178 | all | phecode |
| 802 | Fracture of pelvis | Injuries & Poisonings | 0.937 | 0.841 – 1.04 | 0.232 | 380 | 3765 | all | phecode |
| 803 | Fracture of upper limb | Injuries & Poisonings | 0.968 | 0.924 – 1.01 | 0.164 | 2051 | 20360 | all | phecode |
| 803.1 | Fracture of humerus | Injuries & Poisonings | 0.981 | 0.907 – 1.06 | 0.625 | 734 | 7322 | all | phecode |
| 803.2 | Fracture of radius and ulna | Injuries & Poisonings | 0.949 | 0.891 – 1.01 | 0.103 | 1112 | 11075 | all | phecode |
| 803.21 | Colles' fracture | Injuries & Poisonings | 0.987 | 0.869 – 1.12 | 0.836 | 291 | 2904 | all | phecode |
| 803.3 | Fracture of clavicle or scapula | Injuries & Poisonings | 0.979 | 0.892 – 1.07 | 0.648 | 514 | 5140 | all | phecode |
| 804 | Fracture of hand or wrist | Injuries & Poisonings | 0.968 | 0.919 – 1.02 | 0.227 | 1628 | 16042 | all | phecode |
| 805 |
Fracture of vertebral column without mention ofFracture of vertebral column without mention of spinal cord injury
|
Injuries & Poisonings | 1.03 | 0.972 – 1.09 | 0.31 | 1336 | 13242 | all | phecode |
| 807 | Fracture of ribs | Injuries & Poisonings | 0.935 | 0.863 – 1.01 | 0.1 | 683 | 6815 | all | phecode |
| 809 | Fracture of unspecified bones | Injuries & Poisonings | 0.991 | 0.953 – 1.03 | 0.635 | 2941 | 28633 | all | phecode |
| 816 | Cerebral laceration and contusion | Injuries & Poisonings | 1.21 | 0.904 – 1.62 | 0.199 | 54 | 531 | all | phecode |
| 817 | Concussion | Injuries & Poisonings | 1.03 | 0.966 – 1.1 | 0.358 | 1018 | 10149 | all | phecode |
| 818 | Intracranial hemorrhage (injury) | Injuries & Poisonings | 1.02 | 0.912 – 1.15 | 0.682 | 311 | 3104 | all | phecode |
| 818.1 | Subdural hemorrhage (injury) | Injuries & Poisonings | 1.13 | 0.909 – 1.41 | 0.271 | 90 | 895 | all | phecode |
| 818.2 | Subarachnoid hemorrhage (injury) | Injuries & Poisonings | 1.1 | 0.896 – 1.35 | 0.367 | 97 | 970 | all | phecode |
| 819 |
Skull and face fracture and other intercranialSkull and face fracture and other intercranial injury
|
Injuries & Poisonings | 1.04 | 0.991 – 1.08 | 0.121 | 2287 | 22671 | all | phecode |
| 830 | Dislocation | Injuries & Poisonings | 0.965 | 0.932 – 0.998 | 0.0386 | 3862 | 34720 | all | phecode |
| 835 | Internal derangement of knee | Injuries & Poisonings | 0.974 | 0.932 – 1.02 | 0.256 | 2231 | 21628 | all | phecode |
| 836 | Traumatic arthropathy | Injuries & Poisonings | 0.979 | 0.891 – 1.08 | 0.658 | 496 | 4954 | all | phecode |
| 840 | Sprains and strains | Injuries & Poisonings | 0.988 | 0.963 – 1.01 | 0.343 | 7838 | 37998 | all | phecode |
| 840.1 | Muscle/tendon sprain | Injuries & Poisonings | 0.971 | 0.886 – 1.06 | 0.524 | 537 | 5356 | all | phecode |
| 840.2 | Rotator cuff (capsule) sprain | Injuries & Poisonings | 1.04 | 0.984 – 1.09 | 0.181 | 1640 | 16263 | all | phecode |
| 840.3 | Joint/ligament sprain | Injuries & Poisonings | 0.975 | 0.937 – 1.01 | 0.215 | 2875 | 24879 | all | phecode |
| 841 | Sprains and strains of back and neck | Injuries & Poisonings | 1.03 | 0.978 – 1.09 | 0.253 | 1583 | 15592 | all | phecode |
| 842 | Other sprains and strains | Injuries & Poisonings | 0.992 | 0.938 – 1.05 | 0.773 | 1407 | 13924 | all | phecode |
| 850 | Hemorrhage or hematoma complicating a procedure | Injuries & Poisonings | 1.04 | 0.988 – 1.08 | 0.144 | 2072 | 20649 | all | phecode |
| 851 |
Complications of transplants and reattachedComplications of transplants and reattached limbs
|
Injuries & Poisonings | 1.08 | 1.04 – 1.12 | 9.32e-05 | 2982 | 27545 | all | phecode |
| 853 | Complication of colostomy or enterostomy | Injuries & Poisonings | 1.02 | 0.926 – 1.12 | 0.685 | 460 | 4600 | all | phecode |
| 854 |
Complications of cardiac/vascular deviceComplications of cardiac/vascular device, implant, and graft
|
Injuries & Poisonings | 1.04 | 0.989 – 1.09 | 0.135 | 1985 | 19675 | all | phecode |
| 855 |
Complication of nervous system device, implantComplication of nervous system device, implant, and graft
|
Injuries & Poisonings | 1.02 | 0.9 – 1.16 | 0.732 | 264 | 2640 | all | phecode |
| 856 |
Vascular complications of surgery and medicalVascular complications of surgery and medical procedures
|
Injuries & Poisonings | 0.906 | 0.8 – 1.03 | 0.117 | 293 | 2929 | all | phecode |
| 857 |
Mechanical complication of unspecifiedMechanical complication of unspecified genitourinary device, implant, and graft
|
Injuries & Poisonings | 1.02 | 0.959 – 1.08 | 0.583 | 1310 | 13087 | all | phecode |
| 858 | Complication of internal orthopedic device | Injuries & Poisonings | 1.04 | 0.999 – 1.09 | 0.0568 | 2213 | 21944 | all | phecode |
| 859 |
Complication due to other implant and internalComplication due to other implant and internal device
|
Injuries & Poisonings | 1.06 | 1.02 – 1.11 | 0.0091 | 2110 | 21070 | all | phecode |
| 860 | Bone marrow or stem cell transplant | Neoplasms | 0.876 | 0.745 – 1.03 | 0.112 | 166 | 1660 | all | phecode |
| 870 | Open wounds of head; neck; and trunk | Injuries & Poisonings | 1.04 | 1.01 – 1.08 | 0.0146 | 4117 | 36734 | all | phecode |
| 870.1 | Open wound or laceration of eye or eyelid | Injuries & Poisonings | 0.968 | 0.833 – 1.12 | 0.668 | 204 | 2026 | all | phecode |
| 870.2 | Open wound of ear | Injuries & Poisonings | 1.2 | 1.01 – 1.43 | 0.0408 | 144 | 1437 | all | phecode |
| 870.3 | Other open wound of head and face | Injuries & Poisonings | 1.02 | 0.959 – 1.08 | 0.592 | 1346 | 13301 | all | phecode |
| 870.4 | Open wound of nose and sinus | Injuries & Poisonings | 0.9 | 0.779 – 1.04 | 0.148 | 207 | 2057 | all | phecode |
| 870.5 | Open wound of lip and mouth | Injuries & Poisonings | 1.03 | 0.908 – 1.17 | 0.632 | 275 | 2724 | all | phecode |
| 870.6 | Open wound of neck | Injuries & Poisonings | 1.09 | 0.936 – 1.26 | 0.276 | 214 | 2128 | all | phecode |
| 870.8 | Open wound of genital organs | Injuries & Poisonings | 1.02 | 0.855 – 1.21 | 0.844 | 144 | 1440 | all | phecode |
| 871 | Open wounds of extremities | Injuries & Poisonings | 0.998 | 0.963 – 1.03 | 0.917 | 3530 | 32903 | all | phecode |
| 871.1 | Open wound of hand except finger(s) | Injuries & Poisonings | 0.959 | 0.878 – 1.05 | 0.348 | 572 | 5701 | all | phecode |
| 871.2 | Open wound of finger(s) | Injuries & Poisonings | 0.973 | 0.91 – 1.04 | 0.419 | 984 | 9772 | all | phecode |
| 871.3 | Open wound of foot except toe(s) alone | Injuries & Poisonings | 1.03 | 0.934 – 1.13 | 0.578 | 490 | 4843 | all | phecode |
| 871.4 | Open wound of toe(s) | Injuries & Poisonings | 0.948 | 0.838 – 1.07 | 0.4 | 295 | 2921 | all | phecode |
| 872 | Traumatic amputation | Injuries & Poisonings | 1.14 | 1.04 – 1.24 | 0.0044 | 551 | 5477 | all | phecode |
| 874 | Complication of amputation stump | Injuries & Poisonings | 1.26 | 1.07 – 1.47 | 0.00476 | 170 | 1697 | all | phecode |
| 875 | Non-healing surgical wound | Injuries & Poisonings | 1.14 | 1.04 – 1.24 | 0.00341 | 572 | 5720 | all | phecode |
| 876 |
Posttraumatic wound infection not elsewherePosttraumatic wound infection not elsewhere classified
|
Injuries & Poisonings | 1.05 | 0.98 – 1.13 | 0.154 | 802 | 8003 | all | phecode |
| 907 | Injuries to the nervous system | Injuries & Poisonings | 1.02 | 0.956 – 1.09 | 0.53 | 1010 | 10096 | all | phecode |
| 910 | Superficial injury, infected | Injuries & Poisonings | 0.864 | 0.712 – 1.05 | 0.141 | 119 | 1161 | all | phecode |
| 911 | Blister | Injuries & Poisonings | 1.02 | 0.908 – 1.16 | 0.699 | 302 | 2996 | all | phecode |
| 912 | Insect bite | Injuries & Poisonings | 0.959 | 0.871 – 1.06 | 0.403 | 492 | 4886 | all | phecode |
| 913 | Toxic effect of venom | Injuries & Poisonings | 1.08 | 0.96 – 1.2 | 0.211 | 337 | 3326 | all | phecode |
| 916 | Contusion | Injuries & Poisonings | 1.01 | 0.976 – 1.04 | 0.642 | 4296 | 38033 | all | phecode |
| 930 | Allergic reaction to food | Injuries & Poisonings | 0.951 | 0.882 – 1.03 | 0.198 | 763 | 7596 | all | phecode |
| 931 |
Contact dermatitis and other eczema due toContact dermatitis and other eczema due to plants [except food]
|
Dermatologic | 0.868 | 0.801 – 0.939 | 0.000453 | 714 | 7072 | all | phecode |
| 938 | Dermatitis due to solar radiation | Dermatologic | 0.913 | 0.886 – 0.94 | 2.38e-09 | 5567 | 29098 | all | phecode |
| 938.1 | Acute dermatitis due to solar radiation | Dermatologic | 0.941 | 0.815 – 1.09 | 0.406 | 217 | 2164 | all | phecode |
| 938.2 | Chronic dermatitis due to solar radiation | Dermatologic | 0.909 | 0.882 – 0.937 | 1.17e-09 | 5307 | 28656 | all | phecode |
| 939 |
Atopic/contact dermatitis due to other orAtopic/contact dermatitis due to other or unspecified
|
Dermatologic | 0.948 | 0.922 – 0.974 | 0.000124 | 6704 | 32389 | all | phecode |
| 939.1 | Contact and allergic dermatitis of eyelid | Dermatologic | 0.902 | 0.72 – 1.13 | 0.365 | 91 | 870 | all | phecode |
| 941 | Adverse reaction to serum or vaccine | Injuries & Poisonings | 0.926 | 0.799 – 1.07 | 0.314 | 188 | 1880 | all | phecode |
| 942 | Infusion and transfusion reaction | Injuries & Poisonings | 0.995 | 0.876 – 1.13 | 0.944 | 269 | 2688 | all | phecode |
| 946 | Anaphylactic shock NOS | Injuries & Poisonings | 0.972 | 0.884 – 1.07 | 0.546 | 500 | 4940 | all | phecode |
| 947 | Urticaria | Dermatologic | 0.946 | 0.889 – 1.01 | 0.0779 | 1177 | 11454 | all | phecode |
| 949 | Allergies, other | Injuries & Poisonings | 0.97 | 0.944 – 0.996 | 0.0228 | 7251 | 32350 | all | phecode |
| 952 |
Spinal cord injury without evidence of spinalSpinal cord injury without evidence of spinal bone injury
|
Injuries & Poisonings | 1.09 | 0.991 – 1.2 | 0.0775 | 494 | 4940 | all | phecode |
| 957 | Injury to other and unspecified nerves | Injuries & Poisonings | 1.08 | 0.903 – 1.3 | 0.393 | 136 | 1352 | all | phecode |
| 958 |
Certain early complications of trauma orCertain early complications of trauma or procedure
|
Injuries & Poisonings | 1.06 | 0.995 – 1.12 | 0.0706 | 1217 | 12158 | all | phecode |
| 958.1 | Postoperative shock | Injuries & Poisonings | 0.946 | 0.806 – 1.11 | 0.498 | 169 | 1688 | all | phecode |
| 958.2 | Traumatic and surgical subcutaneous emphysema | Injuries & Poisonings | 1.22 | 1 – 1.49 | 0.0482 | 114 | 1140 | all | phecode |
| 960 | Poisoning by antibiotics | Injuries & Poisonings | 1.05 | 1 – 1.09 | 0.039 | 2479 | 22087 | all | phecode |
| 960.1 |
Adverse effects of antibacterials (notAdverse effects of antibacterials (not penicillins)
|
Injuries & Poisonings | 0.998 | 0.892 – 1.12 | 0.972 | 342 | 3403 | all | phecode |
| 960.2 | Allergy/adverse effect of penicillin | Injuries & Poisonings | 1.03 | 0.981 – 1.09 | 0.216 | 1636 | 16005 | all | phecode |
| 961 | Poisoning by other anti-infectives | Injuries & Poisonings | 0.985 | 0.899 – 1.08 | 0.743 | 528 | 5234 | all | phecode |
| 961.1 | Poisoning/allergy of sulfonamides | Injuries & Poisonings | 1.05 | 0.983 – 1.12 | 0.151 | 1065 | 10347 | all | phecode |
| 962 | Poisoning by hormones and synthetic substitutes | Injuries & Poisonings | 1.02 | 0.947 – 1.1 | 0.59 | 803 | 7976 | all | phecode |
| 962.1 |
Adrenal cortical steroids causing adverseAdrenal cortical steroids causing adverse effects in therapeutic use
|
Injuries & Poisonings | 1.05 | 0.941 – 1.17 | 0.394 | 379 | 3782 | all | phecode |
| 962.2 |
Insulins and antidiabetic agents causingInsulins and antidiabetic agents causing adverse effects in therapeutic use
|
Injuries & Poisonings | 1.14 | 0.873 – 1.49 | 0.336 | 62 | 612 | all | phecode |
| 962.3 |
Hormones and synthetic substitutes causingHormones and synthetic substitutes causing adverse effects in therapeutic use
|
Injuries & Poisonings | 1.02 | 0.923 – 1.12 | 0.74 | 478 | 4773 | all | phecode |
| 963 | Poisoning by primarily systemic agents | Injuries & Poisonings | 1.01 | 0.968 – 1.05 | 0.675 | 2533 | 24531 | all | phecode |
| 963.1 |
Antineoplastic and immunosuppressive drugsAntineoplastic and immunosuppressive drugs causing adverse effects
|
Injuries & Poisonings | 1.01 | 0.965 – 1.05 | 0.762 | 2469 | 24057 | all | phecode |
| 964 |
Poisoning by agents primarily affecting bloodPoisoning by agents primarily affecting blood constituents
|
Injuries & Poisonings | 0.96 | 0.889 – 1.04 | 0.305 | 743 | 7337 | all | phecode |
| 964.1 | Anticoagulants causing adverse effects | Injuries & Poisonings | 0.969 | 0.896 – 1.05 | 0.436 | 712 | 7027 | all | phecode |
| 965 |
Poisoning by analgesics, antipyretics, andPoisoning by analgesics, antipyretics, and antirheumatics
|
Injuries & Poisonings | 1.08 | 1.01 – 1.16 | 0.0306 | 864 | 8601 | all | phecode |
| 965.1 |
Opiates and related narcotics causing adverseOpiates and related narcotics causing adverse effects in therapeutic use
|
Injuries & Poisonings | 1.08 | 1.02 – 1.14 | 0.00479 | 1469 | 14402 | all | phecode |
| 965.3 |
Salicylates causing adverse effects inSalicylates causing adverse effects in therapeutic use
|
Injuries & Poisonings | 1.03 | 0.848 – 1.24 | 0.783 | 119 | 1182 | all | phecode |
| 966 |
Poisoning by anticonvulsants andPoisoning by anticonvulsants and anti-Parkinsonism drugs
|
Injuries & Poisonings | 0.934 | 0.762 – 1.14 | 0.51 | 103 | 1006 | all | phecode |
| 967 |
Adverse effects of sedatives or other centralAdverse effects of sedatives or other central nervous system depressants and anesthetics
|
Injuries & Poisonings | 1 | 0.945 – 1.06 | 0.935 | 1254 | 12464 | all | phecode |
| 969 | Poisoning by psychotropic agents | Injuries & Poisonings | 1.23 | 1.08 – 1.39 | 0.00133 | 281 | 2797 | all | phecode |
| 971 |
Poisoning by drugs primarily affecting thePoisoning by drugs primarily affecting the autonomic nervous system
|
Injuries & Poisonings | 0.82 | 0.635 – 1.06 | 0.128 | 67 | 643 | all | phecode |
| 972 |
Poisoning by agents primarily affecting thePoisoning by agents primarily affecting the cardiovascular system
|
Injuries & Poisonings | 1.04 | 0.92 – 1.17 | 0.541 | 288 | 2858 | all | phecode |
| 972.1 |
Cardiac rhythm regulators causing adverseCardiac rhythm regulators causing adverse effects in therapeutic use
|
Injuries & Poisonings | 1.15 | 0.913 – 1.44 | 0.241 | 80 | 776 | all | phecode |
| 972.6 | Antihypertensive agents causing adverse effects | Injuries & Poisonings | 0.958 | 0.787 – 1.17 | 0.674 | 104 | 1034 | all | phecode |
| 974 |
Poisoning by water, mineral, and uric acidPoisoning by water, mineral, and uric acid metabolism drugs
|
Injuries & Poisonings | 1.07 | 0.884 – 1.31 | 0.469 | 113 | 1130 | all | phecode |
| 975 |
Poisoning by agents primarily acting on thePoisoning by agents primarily acting on the smooth and skeletal muscles and respiratory system
|
Injuries & Poisonings | 1.07 | 0.85 – 1.36 | 0.55 | 81 | 810 | all | phecode |
| 976 |
Poisoning by agents primarily affecting skin &Poisoning by agents primarily affecting skin & mucous membrane, ophthalmological, otorhinolaryngological, & dental drugs
|
Injuries & Poisonings | 1.08 | 0.851 – 1.38 | 0.511 | 71 | 703 | all | phecode |
| 977 | Personal history of allergy to medicinal agents | Injuries & Poisonings | 1.02 | 0.965 – 1.07 | 0.56 | 1763 | 16599 | all | phecode |
| 979 | Adverse drug events and drug allergies | Injuries & Poisonings | 1.02 | 0.987 – 1.06 | 0.206 | 3448 | 30885 | all | phecode |
| 980 |
Encounter for long-term (current) use ofEncounter for long-term (current) use of antibiotics
|
Infectious Diseases | 1.01 | 0.95 – 1.07 | 0.841 | 1391 | 13877 | all | phecode |
| 985 | Toxic effect of other metals | Injuries & Poisonings | 1.03 | 0.788 – 1.34 | 0.843 | 57 | 564 | all | phecode |
| 989 |
Toxic effect of other substances, chieflyToxic effect of other substances, chiefly nonmedicinal as to source
|
Injuries & Poisonings | 1.17 | 0.975 – 1.41 | 0.0913 | 129 | 1275 | all | phecode |
| 990 | Effects radiation NOS | Injuries & Poisonings | 1.02 | 0.986 – 1.06 | 0.248 | 3927 | 31223 | all | phecode |
| 994 | Sepsis and SIRS | Injuries & Poisonings | 1.06 | 1.01 – 1.11 | 0.0108 | 2192 | 21710 | all | phecode |
| 994.1 | Systemic inflammatory response syndrome (SIRS) | Injuries & Poisonings | 1.12 | 0.992 – 1.26 | 0.067 | 291 | 2910 | all | phecode |
| 994.2 | Sepsis | Injuries & Poisonings | 1.05 | 1.01 – 1.1 | 0.0236 | 2086 | 20666 | all | phecode |
| 994.21 | Septic shock | Injuries & Poisonings | 1.06 | 0.977 – 1.16 | 0.154 | 627 | 6260 | all | phecode |
| 008 | Intestinal infection | Infectious Diseases | 1 | 0.957 – 1.05 | 0.889 | 1979 | 19813 | exclusion | phecode |
| 008.5 | Bacterial enteritis | Infectious Diseases | 1.05 | 0.974 – 1.13 | 0.214 | 835 | 8614 | exclusion | phecode |
| 008.52 | Intestinal infection due to C. difficile | Infectious Diseases | 1.06 | 0.973 – 1.15 | 0.189 | 649 | 6801 | exclusion | phecode |
| 008.6 | Viral Enteritis | Infectious Diseases | 1.07 | 0.977 – 1.18 | 0.139 | 517 | 5335 | exclusion | phecode |
| 010 | Tuberculosis | Infectious Diseases | 1.12 | 0.945 – 1.33 | 0.19 | 149 | 1538 | exclusion | phecode |
| 031 | Diseases due to other mycobacteria | Infectious Diseases | 0.978 | 0.734 – 1.3 | 0.879 | 56 | 552 | exclusion | phecode |
| 038 | Septicemia | Infectious Diseases | 1.1 | 1.05 – 1.16 | 0.000341 | 1514 | 15673 | exclusion | phecode |
| 038.1 | Gram negative septicemia | Infectious Diseases | 1.03 | 0.915 – 1.15 | 0.655 | 336 | 3430 | exclusion | phecode |
| 038.2 | Gram positive septicemia | Infectious Diseases | 1.09 | 0.906 – 1.32 | 0.35 | 126 | 1484 | exclusion | phecode |
| 038.3 | Bacteremia | Infectious Diseases | 1.16 | 1.07 – 1.25 | 0.000256 | 712 | 7477 | exclusion | phecode |
| 041 | Bacterial infection NOS | Infectious Diseases | 1.12 | 1.08 – 1.16 | 2.71e-10 | 3692 | 26206 | exclusion | phecode |
| 041.1 | Staphylococcus infections | Infectious Diseases | 1.13 | 1.06 – 1.2 | 0.000262 | 1076 | 11185 | exclusion | phecode |
| 041.11 | Methicillin sensitive Staphylococcus aureus | Infectious Diseases | 1.09 | 0.997 – 1.18 | 0.059 | 582 | 6022 | exclusion | phecode |
| 041.12 | Methicillin resistant Staphylococcus aureus | Infectious Diseases | 1.17 | 1.07 – 1.29 | 0.000938 | 487 | 5208 | exclusion | phecode |
| 041.2 | Streptococcus infection | Infectious Diseases | 1.1 | 1.03 – 1.17 | 0.00636 | 1001 | 10346 | exclusion | phecode |
| 041.21 | Rheumatic fever / chorea | Infectious Diseases | 1.01 | 0.848 – 1.2 | 0.913 | 155 | 1568 | exclusion | phecode |
| 041.4 | E. coli | Infectious Diseases | 1.2 | 1.11 – 1.29 | 7.27e-06 | 733 | 7512 | exclusion | phecode |
| 041.8 | H. pylori | Infectious Diseases | 1.04 | 0.885 – 1.22 | 0.653 | 171 | 1669 | exclusion | phecode |
| 041.9 | Infection with drug-resistant microorganisms | Infectious Diseases | 1.04 | 0.905 – 1.19 | 0.602 | 234 | 2494 | exclusion | phecode |
| 053 | Herpes zoster | Infectious Diseases | 1.02 | 0.95 – 1.09 | 0.63 | 1001 | 9536 | exclusion | phecode |
| 053.1 | Herpes zoster with nervous system complications | Infectious Diseases | 0.976 | 0.819 – 1.16 | 0.784 | 139 | 1339 | exclusion | phecode |
| 054 | Herpes simplex | Infectious Diseases | 0.991 | 0.93 – 1.06 | 0.791 | 1093 | 10750 | exclusion | phecode |
| 070 | Viral hepatitis | Infectious Diseases | 1.26 | 1.15 – 1.38 | 1e-06 | 519 | 5274 | exclusion | phecode |
| 070.1 | Viral hepatitis A | Infectious Diseases | 1.04 | 0.788 – 1.36 | 0.795 | 60 | 513 | exclusion | phecode |
| 070.2 | Viral hepatitis B | Infectious Diseases | 1.15 | 0.965 – 1.38 | 0.116 | 138 | 1331 | exclusion | phecode |
| 070.3 | Viral hepatitis C | Infectious Diseases | 1.37 | 1.22 – 1.54 | 1.51e-07 | 322 | 3365 | exclusion | phecode |
| 070.4 | Chronic hepatitis | Infectious Diseases | 0.96 | 0.791 – 1.16 | 0.677 | 119 | 1257 | exclusion | phecode |
| 070.9 | Hepatitis NOS | Infectious Diseases | 1.12 | 1.03 – 1.21 | 0.00502 | 718 | 7030 | exclusion | phecode |
| 071 | Human immunodeficiency virus [HIV] disease | Infectious Diseases | 1.06 | 0.861 – 1.32 | 0.565 | 102 | 1033 | exclusion | phecode |
| 071.1 | HIV infection, symptomatic | Infectious Diseases | 0.933 | 0.737 – 1.18 | 0.568 | 82 | 830 | exclusion | phecode |
| 078 | Viral warts & HPV | Infectious Diseases | 0.96 | 0.92 – 1 | 0.0583 | 2525 | 20366 | exclusion | phecode |
| 079 | Viral infection | Infectious Diseases | 0.978 | 0.947 – 1.01 | 0.183 | 4582 | 23700 | exclusion | phecode |
| 079.1 | Varicella infection | Infectious Diseases | 0.927 | 0.888 – 0.967 | 0.000443 | 2537 | 20618 | exclusion | phecode |
| 079.2 | Infectious mononucleosis | Infectious Diseases | 1.04 | 0.902 – 1.19 | 0.618 | 234 | 2156 | exclusion | phecode |
| 079.9 | Viremia, NOS | Infectious Diseases | 1.04 | 0.957 – 1.14 | 0.327 | 592 | 5795 | exclusion | phecode |
| 080 | Postoperative infection | Infectious Diseases | 1.09 | 1.03 – 1.15 | 0.00124 | 1666 | 17240 | exclusion | phecode |
| 081 |
Infection/inflammation of internal prostheticInfection/inflammation of internal prosthetic device; implant; and graft
|
Infectious Diseases | 1.06 | 0.99 – 1.13 | 0.0966 | 985 | 10266 | exclusion | phecode |
| 090 |
Sexually transmitted infections (not HIV orSexually transmitted infections (not HIV or hepatitis)
|
Infectious Diseases | 1.04 | 0.954 – 1.12 | 0.403 | 670 | 6927 | exclusion | phecode |
| 110 | Dermatophytosis / Dermatomycosis | Infectious Diseases | 1.01 | 0.966 – 1.06 | 0.668 | 2357 | 19541 | exclusion | phecode |
| 110.1 | Dermatophytosis | Infectious Diseases | 1 | 0.959 – 1.05 | 0.842 | 2147 | 17488 | exclusion | phecode |
| 110.11 | Dermatophytosis of nail | Infectious Diseases | 1.03 | 0.972 – 1.1 | 0.293 | 1309 | 10454 | exclusion | phecode |
| 110.12 | Althete's foot | Infectious Diseases | 0.995 | 0.911 – 1.09 | 0.912 | 595 | 4995 | exclusion | phecode |
| 110.13 | Dermatophytosis of the body | Infectious Diseases | 0.961 | 0.879 – 1.05 | 0.383 | 560 | 5163 | exclusion | phecode |
| 110.2 | Dermatomycoses | Infectious Diseases | 1.03 | 0.904 – 1.17 | 0.671 | 279 | 2783 | exclusion | phecode |
| 112 | Candidiasis | Infectious Diseases | 1.06 | 1.02 – 1.11 | 0.00649 | 2487 | 20662 | exclusion | phecode |
| 112.3 | Candidiasis of skin and nails | Infectious Diseases | 1.07 | 0.965 – 1.18 | 0.2 | 426 | 4417 | exclusion | phecode |
| 117 | Mycoses | Infectious Diseases | 1.07 | 0.958 – 1.19 | 0.241 | 378 | 4031 | exclusion | phecode |
| 117.1 | Histoplasmosis | Infectious Diseases | 1.14 | 0.831 – 1.55 | 0.425 | 40 | 527 | exclusion | phecode |
| 117.4 | Aspergillosis | Infectious Diseases | 1.07 | 0.852 – 1.34 | 0.574 | 79 | 941 | exclusion | phecode |
| 130 | Spirochetal infection | Infectious Diseases | 0.918 | 0.756 – 1.11 | 0.387 | 124 | 1127 | exclusion | phecode |
| 130.1 | Lyme disease | Infectious Diseases | 0.867 | 0.686 – 1.1 | 0.235 | 83 | 774 | exclusion | phecode |
| 131 | Protozoan infection | Infectious Diseases | 1.28 | 0.955 – 1.71 | 0.0994 | 53 | 465 | exclusion | phecode |
| 132 | Infestation (lice, mites) | Infectious Diseases | 1.17 | 0.988 – 1.38 | 0.0686 | 153 | 1315 | exclusion | phecode |
| 134 | Helminthiases | Infectious Diseases | 1.13 | 0.858 – 1.48 | 0.388 | 61 | 515 | exclusion | phecode |
| 134.1 | Intestinal helminthiases | Infectious Diseases | 1.07 | 0.759 – 1.51 | 0.699 | 39 | 331 | exclusion | phecode |
| 136 | Other infectious and parasitic diseases | Infectious Diseases | 1.06 | 1.01 – 1.11 | 0.0129 | 2131 | 21533 | exclusion | phecode |
| 145 | Cancer of mouth | Neoplasms | 1.03 | 0.958 – 1.11 | 0.425 | 853 | 8858 | exclusion | phecode |
| 145.1 | Cancer of lip | Neoplasms | 1.21 | 0.897 – 1.64 | 0.209 | 43 | 443 | exclusion | phecode |
| 145.2 | Cancer of tongue | Neoplasms | 1.04 | 0.931 – 1.16 | 0.505 | 361 | 3988 | exclusion | phecode |
| 145.3 | Cancer of major salivary glands | Neoplasms | 0.971 | 0.842 – 1.12 | 0.687 | 221 | 2105 | exclusion | phecode |
| 145.4 | Cancer of the gums | Neoplasms | 0.896 | 0.719 – 1.12 | 0.327 | 98 | 925 | exclusion | phecode |
| 145.5 | Cancer of the mouth floor | Neoplasms | 1.17 | 0.963 – 1.41 | 0.116 | 117 | 1261 | exclusion | phecode |
| 149 | Cancer of larynx, pharynx, nasal cavities | Neoplasms | 1.06 | 0.979 – 1.14 | 0.156 | 703 | 7736 | exclusion | phecode |
| 149.1 | Cancer of oropharynx | Neoplasms | 1.01 | 0.867 – 1.17 | 0.936 | 197 | 2129 | exclusion | phecode |
| 149.2 | Cancer of nasopharynx | Neoplasms | 1.3 | 1 – 1.69 | 0.0489 | 62 | 620 | exclusion | phecode |
| 149.3 | Cancer of hypopharynx | Neoplasms | 1.09 | 0.799 – 1.47 | 0.601 | 43 | 492 | exclusion | phecode |
| 149.4 | Cancer of larynx | Neoplasms | 1.18 | 1.01 – 1.38 | 0.0406 | 174 | 2255 | exclusion | phecode |
| 149.5 |
Hx of malignant neoplasm of oral cavity andHx of malignant neoplasm of oral cavity and pharynx
|
Neoplasms | 1.08 | 0.955 – 1.22 | 0.223 | 294 | 3236 | exclusion | phecode |
| 149.9 | Cancer of of nasal cavities | Neoplasms | 1 | 0.844 – 1.2 | 0.962 | 143 | 1504 | exclusion | phecode |
| 150 | Cancer of esophagus | Neoplasms | 1.06 | 0.911 – 1.24 | 0.442 | 176 | 2517 | exclusion | phecode |
| 151 | Cancer of stomach | Neoplasms | 0.995 | 0.87 – 1.14 | 0.945 | 235 | 2915 | exclusion | phecode |
| 153 | Colorectal cancer | Neoplasms | 0.994 | 0.925 – 1.07 | 0.87 | 862 | 8888 | exclusion | phecode |
| 153.2 | Colon cancer | Neoplasms | 0.983 | 0.907 – 1.07 | 0.681 | 677 | 6999 | exclusion | phecode |
| 153.3 |
Malignant neoplasm of rectum, rectosigmoidMalignant neoplasm of rectum, rectosigmoid junction, and anus
|
Neoplasms | 0.977 | 0.889 – 1.07 | 0.634 | 494 | 5172 | exclusion | phecode |
| 155 | Cancer of liver and intrahepatic bile duct | Neoplasms | 1.12 | 0.985 – 1.26 | 0.0847 | 296 | 3118 | exclusion | phecode |
| 155.1 | Malignant neoplasm of liver, primary | Neoplasms | 1.22 | 1.05 – 1.42 | 0.00909 | 197 | 2078 | exclusion | phecode |
| 157 | Pancreatic cancer | Neoplasms | 1.08 | 0.957 – 1.22 | 0.214 | 303 | 2953 | exclusion | phecode |
| 158 |
Neoplasm of unspecified nature of digestiveNeoplasm of unspecified nature of digestive system
|
Neoplasms | 1.01 | 0.944 – 1.08 | 0.788 | 965 | 9630 | exclusion | phecode |
| 159 |
Malignant neoplasm of other and ill-definedMalignant neoplasm of other and ill-defined sites within the digestive organs and peritoneum
|
Neoplasms | 1.03 | 0.968 – 1.1 | 0.331 | 1050 | 10945 | exclusion | phecode |
| 159.2 |
Malignant neoplasm of small intestineMalignant neoplasm of small intestine, including duodenum
|
Neoplasms | 1.09 | 0.905 – 1.31 | 0.364 | 127 | 1368 | exclusion | phecode |
| 159.3 |
Malignant neoplasm of gallbladder andMalignant neoplasm of gallbladder and extrahepatic bile ducts
|
Neoplasms | 1.24 | 0.988 – 1.55 | 0.0642 | 92 | 915 | exclusion | phecode |
| 159.4 |
Malignant neoplasm of retroperitoneum andMalignant neoplasm of retroperitoneum and peritoneum
|
Neoplasms | 0.971 | 0.834 – 1.13 | 0.701 | 184 | 1878 | exclusion | phecode |
| 164 | Cancer of intrathoracic organs | Neoplasms | 0.958 | 0.755 – 1.22 | 0.721 | 79 | 793 | exclusion | phecode |
| 165 | Cancer within the respiratory system | Neoplasms | 1.09 | 1.01 – 1.19 | 0.0356 | 643 | 7867 | exclusion | phecode |
| 165.1 | Cancer of bronchus; lung | Neoplasms | 1.11 | 1.01 – 1.22 | 0.027 | 503 | 6242 | exclusion | phecode |
| 170 | Cancer of bone and connective tissue | Neoplasms | 0.998 | 0.936 – 1.06 | 0.941 | 1110 | 11053 | exclusion | phecode |
| 170.1 | Bone cancer | Neoplasms | 1 | 0.911 – 1.11 | 0.947 | 484 | 4749 | exclusion | phecode |
| 170.2 | Cancer of connective tissue | Neoplasms | 0.988 | 0.917 – 1.07 | 0.761 | 787 | 7911 | exclusion | phecode |
| 172 | Skin cancer | Neoplasms | 0.956 | 0.925 – 0.987 | 0.00585 | 5144 | 22144 | exclusion | phecode |
| 172.1 | Melanomas of skin, dx or hx | Neoplasms | 0.95 | 0.914 – 0.987 | 0.0093 | 3255 | 19687 | exclusion | phecode |
| 172.11 | Melanomas of skin | Neoplasms | 0.976 | 0.929 – 1.02 | 0.318 | 1932 | 15986 | exclusion | phecode |
| 172.2 | Other non-epithelial cancer of skin | Neoplasms | 0.95 | 0.916 – 0.984 | 0.00434 | 4147 | 19948 | exclusion | phecode |
| 172.21 | Basal cell carcinoma | Neoplasms | 0.924 | 0.882 – 0.968 | 0.000911 | 2197 | 14852 | exclusion | phecode |
| 172.22 | Squamous cell carcinoma | Neoplasms | 0.966 | 0.91 – 1.02 | 0.249 | 1313 | 10488 | exclusion | phecode |
| 172.3 | Carcinoma in situ of skin | Neoplasms | 0.908 | 0.844 – 0.977 | 0.01 | 855 | 7093 | exclusion | phecode |
| 173 | Neoplasm of uncertain behavior of skin | Neoplasms | 0.948 | 0.893 – 1.01 | 0.0767 | 1269 | 11855 | exclusion | phecode |
| 174 | Breast cancer | Neoplasms | 0.946 | 0.9 – 0.993 | 0.0249 | 2101 | 10762 | exclusion | phecode |
| 174.1 | Breast cancer [female] | Neoplasms | 0.934 | 0.889 – 0.983 | 0.00818 | 1999 | 10276 | exclusion | phecode |
| 174.11 | Malignant neoplasm of female breast | Neoplasms | 0.934 | 0.888 – 0.983 | 0.00837 | 1973 | 10224 | exclusion | phecode |
| 174.3 | Neoplasm of uncertain behavior of breast | Neoplasms | 1.09 | 0.919 – 1.29 | 0.325 | 158 | 1556 | exclusion | phecode |
| 175 | Acquired absence of breast | Neoplasms | 0.939 | 0.861 – 1.02 | 0.154 | 592 | 6177 | exclusion | phecode |
| 180 | Cervical cancer and dysplasia | Neoplasms | 1.09 | 1.02 – 1.16 | 0.0094 | 1066 | 8829 | exclusion | phecode |
| 180.1 | Cervical cancer | Neoplasms | 1.2 | 1.07 – 1.34 | 0.00209 | 349 | 3509 | exclusion | phecode |
| 180.3 |
Cervical intraepithelial neoplasia [CIN]Cervical intraepithelial neoplasia [CIN] [Cervical dysplasia]
|
Neoplasms | 1.04 | 0.966 – 1.12 | 0.293 | 808 | 6943 | exclusion | phecode |
| 182 | Malignant neoplasm of uterus | Neoplasms | 0.964 | 0.879 – 1.06 | 0.439 | 537 | 4960 | exclusion | phecode |
| 184 | Cancer of other female genital organs | Neoplasms | 1.03 | 0.958 – 1.11 | 0.404 | 798 | 7862 | exclusion | phecode |
| 184.1 |
Malignant neoplasm of ovary and other uterineMalignant neoplasm of ovary and other uterine adnexa
|
Neoplasms | 0.988 | 0.886 – 1.1 | 0.823 | 383 | 3797 | exclusion | phecode |
| 184.11 | Malignant neoplasm of ovary | Neoplasms | 0.909 | 0.803 – 1.03 | 0.131 | 290 | 2881 | exclusion | phecode |
| 184.2 |
Cancer of other female genital organsCancer of other female genital organs (excluding uterus and ovary)
|
Neoplasms | 1.08 | 0.976 – 1.21 | 0.13 | 408 | 4115 | exclusion | phecode |
| 185 | Cancer of prostate | Neoplasms | 0.941 | 0.886 – 0.999 | 0.0456 | 1510 | 6145 | exclusion | phecode |
| 187 | Cancer of other male genital organs | Neoplasms | 1.02 | 0.883 – 1.18 | 0.785 | 204 | 2076 | exclusion | phecode |
| 187.1 |
Malignant neoplasm of unspecified male genitalMalignant neoplasm of unspecified male genital organ
|
Neoplasms | 1.05 | 0.808 – 1.36 | 0.718 | 60 | 619 | exclusion | phecode |
| 187.2 | Malignant neoplasm of testis | Neoplasms | 1.02 | 0.842 – 1.23 | 0.845 | 123 | 1234 | exclusion | phecode |
| 187.8 |
Neoplasm of uncertain behavior of male genitalNeoplasm of uncertain behavior of male genital organs
|
Neoplasms | 1.1 | 0.76 – 1.6 | 0.603 | 31 | 304 | exclusion | phecode |
| 189 |
Cancer of urinary organs (incl. kidney andCancer of urinary organs (incl. kidney and bladder)
|
Neoplasms | 1.07 | 1.01 – 1.13 | 0.0123 | 1546 | 14420 | exclusion | phecode |
| 189.1 | Cancer of kidney and renal pelvis | Neoplasms | 1.1 | 1.02 – 1.18 | 0.0136 | 834 | 8576 | exclusion | phecode |
| 189.11 | Malignant neoplasm of kidney, except pelvis | Neoplasms | 1.12 | 1.03 – 1.21 | 0.00552 | 738 | 7524 | exclusion | phecode |
| 189.12 | Malignant neoplasm of renal pelvis | Neoplasms | 1.14 | 0.945 – 1.37 | 0.172 | 121 | 1254 | exclusion | phecode |
| 189.2 | Cancer of bladder | Neoplasms | 1.09 | 1.01 – 1.17 | 0.0242 | 863 | 8716 | exclusion | phecode |
| 189.21 | Malignant neoplasm of bladder | Neoplasms | 1.1 | 1.02 – 1.18 | 0.0128 | 798 | 8033 | exclusion | phecode |
| 189.4 | Malignant neoplasm of other urinary organs | Neoplasms | 1.13 | 1.01 – 1.27 | 0.0382 | 328 | 3532 | exclusion | phecode |
| 190 | Cancer of eye | Neoplasms | 1.14 | 0.904 – 1.43 | 0.27 | 77 | 788 | exclusion | phecode |
| 191 |
Manlignant and unknown neoplasms of brain andManlignant and unknown neoplasms of brain and nervous system
|
Neoplasms | 1.02 | 0.943 – 1.1 | 0.614 | 722 | 7165 | exclusion | phecode |
| 191.1 | Cancer of brain and nervous system | Neoplasms | 0.974 | 0.885 – 1.07 | 0.595 | 483 | 4704 | exclusion | phecode |
| 191.11 | Cancer of brain | Neoplasms | 0.994 | 0.897 – 1.1 | 0.915 | 424 | 4074 | exclusion | phecode |
| 193 | Thyroid cancer | Neoplasms | 0.992 | 0.913 – 1.08 | 0.846 | 657 | 6389 | exclusion | phecode |
| 194 | Cancer of other endocrine glands | Neoplasms | 1.05 | 0.94 – 1.17 | 0.405 | 392 | 3690 | exclusion | phecode |
| 195 | Cancer, suspected or other | Neoplasms | 0.989 | 0.964 – 1.02 | 0.426 | 10230 | 18819 | exclusion | phecode |
| 195.1 | Malignant neoplasm, other | Neoplasms | 0.989 | 0.963 – 1.02 | 0.418 | 10056 | 18801 | exclusion | phecode |
| 195.3 | Malignant neoplasm of head, face, and neck | Neoplasms | 1.07 | 0.981 – 1.16 | 0.132 | 616 | 6031 | exclusion | phecode |
| 196 | Radiotherapy | Neoplasms | 0.989 | 0.934 – 1.05 | 0.705 | 1446 | 11131 | exclusion | phecode |
| 197 | Chemotherapy | Neoplasms | 0.971 | 0.932 – 1.01 | 0.162 | 2999 | 16587 | exclusion | phecode |
| 198 | Secondary malignant neoplasm | Neoplasms | 1.01 | 0.968 – 1.05 | 0.744 | 3415 | 16337 | exclusion | phecode |
| 198.1 | Secondary malignancy of lymph nodes | Neoplasms | 0.985 | 0.941 – 1.03 | 0.54 | 2179 | 14758 | exclusion | phecode |
| 198.2 | Secondary malignancy of respiratory organs | Neoplasms | 0.917 | 0.842 – 0.998 | 0.0446 | 624 | 6595 | exclusion | phecode |
| 198.3 |
Secondary malignant neoplasm of digestiveSecondary malignant neoplasm of digestive systems
|
Neoplasms | 0.933 | 0.851 – 1.02 | 0.136 | 529 | 5406 | exclusion | phecode |
| 198.4 | Secondary malignant neoplasm of liver | Neoplasms | 0.96 | 0.871 – 1.06 | 0.409 | 468 | 4793 | exclusion | phecode |
| 198.5 | Secondary malignancy of brain/spine | Neoplasms | 1.02 | 0.914 – 1.14 | 0.727 | 367 | 4043 | exclusion | phecode |
| 198.6 | Secondary malignancy of bone | Neoplasms | 1 | 0.914 – 1.1 | 0.94 | 507 | 5196 | exclusion | phecode |
| 198.7 | Secondary malignant neoplasm of skin | Neoplasms | 0.944 | 0.812 – 1.1 | 0.456 | 196 | 1980 | exclusion | phecode |
| 199 | Neoplasm of uncertain behavior | Neoplasms | 1 | 0.968 – 1.04 | 0.807 | 3648 | 18257 | exclusion | phecode |
| 199.4 | Neurofibromatosis | Neoplasms | 0.847 | 0.661 – 1.08 | 0.188 | 68 | 654 | exclusion | phecode |
| 200 | Myeloproliferative disease | Neoplasms | 0.936 | 0.864 – 1.02 | 0.11 | 695 | 7095 | exclusion | phecode |
| 200.1 | Polycythemia vera | Neoplasms | 1.01 | 0.844 – 1.2 | 0.953 | 143 | 1470 | exclusion | phecode |
| 201 | Hodgkin's disease | Neoplasms | 1.01 | 0.831 – 1.22 | 0.942 | 124 | 1119 | exclusion | phecode |
| 202 | Cancer of other lymphoid, histiocytic tissue | Neoplasms | 0.991 | 0.925 – 1.06 | 0.786 | 939 | 9639 | exclusion | phecode |
| 202.2 | Non-Hodgkins lymphoma | Neoplasms | 0.997 | 0.926 – 1.07 | 0.941 | 801 | 8183 | exclusion | phecode |
| 202.21 | Nodular lymphoma | Neoplasms | 0.969 | 0.873 – 1.08 | 0.558 | 406 | 4311 | exclusion | phecode |
| 202.22 | Reticulosarcoma | Neoplasms | 0.994 | 0.807 – 1.22 | 0.952 | 99 | 1016 | exclusion | phecode |
| 202.24 | Large cell lymphoma | Neoplasms | 0.964 | 0.784 – 1.19 | 0.733 | 97 | 950 | exclusion | phecode |
| 204 | Leukemia | Neoplasms | 0.957 | 0.863 – 1.06 | 0.414 | 408 | 4052 | exclusion | phecode |
| 204.1 | Lymphoid leukemia | Neoplasms | 0.925 | 0.774 – 1.1 | 0.387 | 140 | 1400 | exclusion | phecode |
| 204.11 | Lymphoid leukemia, acute | Neoplasms | 0.882 | 0.651 – 1.19 | 0.416 | 50 | 491 | exclusion | phecode |
| 204.12 | Lymphoid leukemia, chronic | Neoplasms | 0.953 | 0.768 – 1.18 | 0.666 | 95 | 942 | exclusion | phecode |
| 204.2 | Myeloid leukemia | Neoplasms | 0.885 | 0.747 – 1.05 | 0.16 | 158 | 1588 | exclusion | phecode |
| 204.21 | Myeloid leukemia, acute | Neoplasms | 0.827 | 0.669 – 1.02 | 0.0805 | 95 | 933 | exclusion | phecode |
| 204.22 | Myeloid leukemia, chronic | Neoplasms | 0.847 | 0.594 – 1.21 | 0.356 | 37 | 368 | exclusion | phecode |
| 204.4 | Multiple myeloma | Neoplasms | 1.04 | 0.864 – 1.24 | 0.698 | 129 | 1204 | exclusion | phecode |
| 208 | Benign neoplasm of colon | Neoplasms | 0.981 | 0.953 – 1.01 | 0.192 | 6518 | 23815 | exclusion | phecode |
| 209 | Neuroendocrine tumors | Neoplasms | 1.04 | 0.88 – 1.22 | 0.668 | 161 | 1608 | exclusion | phecode |
| 210 | Benign neoplasm of lip, oral cavity, and pharynx | Neoplasms | 1.03 | 0.968 – 1.09 | 0.374 | 1249 | 12484 | exclusion | phecode |
| 211 |
Benign neoplasm of other parts of digestiveBenign neoplasm of other parts of digestive system
|
Neoplasms | 1.03 | 0.996 – 1.06 | 0.0869 | 4835 | 24891 | exclusion | phecode |
| 212 |
Benign neoplasm of respiratory andBenign neoplasm of respiratory and intrathoracic organs
|
Neoplasms | 1.05 | 0.985 – 1.12 | 0.139 | 1105 | 11806 | exclusion | phecode |
| 213 | Benign neoplasm of bone and articular cartilage | Neoplasms | 1 | 0.943 – 1.07 | 0.889 | 1132 | 10452 | exclusion | phecode |
| 214 | Lipoma | Neoplasms | 0.957 | 0.894 – 1.02 | 0.211 | 965 | 9297 | exclusion | phecode |
| 214.1 | Lipoma of skin and subcutaneous tissue | Neoplasms | 0.936 | 0.857 – 1.02 | 0.136 | 579 | 5794 | exclusion | phecode |
| 215 |
Other benign neoplasm of connective and otherOther benign neoplasm of connective and other soft tissue
|
Neoplasms | 0.999 | 0.962 – 1.04 | 0.978 | 3022 | 26312 | exclusion | phecode |
| 216 | Benign neoplasm of skin | Neoplasms | 0.952 | 0.927 – 0.978 | 0.000298 | 7774 | 23525 | exclusion | phecode |
| 216.1 | Screening for malignant neoplasms of the skin | Neoplasms | 0.827 | 0.689 – 0.991 | 0.0401 | 123 | 1142 | exclusion | phecode |
| 217 | Vascular hamartomas and non-neoplastic nevi | Neoplasms | 0.907 | 0.852 – 0.965 | 0.00204 | 1161 | 10752 | exclusion | phecode |
| 217.1 | Nevus, non-neoplastic | Neoplasms | 0.883 | 0.828 – 0.942 | 0.000168 | 1083 | 9954 | exclusion | phecode |
| 218 | Benign neoplasm of uterus | Neoplasms | 0.992 | 0.953 – 1.03 | 0.697 | 3182 | 11855 | exclusion | phecode |
| 218.1 | Uterine leiomyoma | Neoplasms | 0.958 | 0.903 – 1.02 | 0.149 | 1326 | 11021 | exclusion | phecode |
| 218.2 | Other benign neoplasm of uterus | Neoplasms | 0.993 | 0.949 – 1.04 | 0.74 | 2547 | 11687 | exclusion | phecode |
| 220 | Benign neoplasm of ovary | Neoplasms | 0.895 | 0.823 – 0.974 | 0.00991 | 635 | 6205 | exclusion | phecode |
| 221 | Benign neoplasm of other female genital organs | Neoplasms | 1.06 | 0.999 – 1.12 | 0.0538 | 1492 | 10223 | exclusion | phecode |
| 222 | Benign neoplasm of male genital organs | Neoplasms | 1.01 | 0.933 – 1.1 | 0.783 | 688 | 5965 | exclusion | phecode |
| 223 |
Benign neoplasm of kidney and other urinaryBenign neoplasm of kidney and other urinary organs
|
Neoplasms | 1.02 | 0.955 – 1.09 | 0.534 | 1021 | 8067 | exclusion | phecode |
| 224 | Benign neoplasm of eye | Neoplasms | 1.04 | 0.941 – 1.15 | 0.43 | 429 | 4158 | exclusion | phecode |
| 224.1 | Benign neoplasm of eye, uveal | Neoplasms | 1.04 | 0.93 – 1.16 | 0.503 | 361 | 3467 | exclusion | phecode |
| 225 |
Benign neoplasm of brain and other parts ofBenign neoplasm of brain and other parts of nervous system
|
Neoplasms | 0.979 | 0.909 – 1.05 | 0.571 | 802 | 7881 | exclusion | phecode |
| 225.1 |
Benign neoplasm of brain, cranial nervesBenign neoplasm of brain, cranial nerves, meninges
|
Neoplasms | 0.978 | 0.899 – 1.06 | 0.599 | 636 | 6171 | exclusion | phecode |
| 225.2 | Benign neoplasm of spinal cord, meninges | Neoplasms | 0.945 | 0.813 – 1.1 | 0.464 | 188 | 1915 | exclusion | phecode |
| 226 | Benign neoplasm of thyroid glands | Neoplasms | 0.988 | 0.92 – 1.06 | 0.729 | 897 | 8863 | exclusion | phecode |
| 227 |
Benign neoplasm of other endocrine glands andBenign neoplasm of other endocrine glands and related structures
|
Neoplasms | 0.981 | 0.921 – 1.05 | 0.561 | 1131 | 11113 | exclusion | phecode |
| 227.1 | Benign neoplasm of adrenal gland | Neoplasms | 1.13 | 1 – 1.28 | 0.0453 | 302 | 2955 | exclusion | phecode |
| 227.2 | Benign neoplasm of parathyroid gland | Neoplasms | 0.884 | 0.805 – 0.971 | 0.0101 | 524 | 5224 | exclusion | phecode |
| 227.3 |
Benign neoplasm of pituitary gland andBenign neoplasm of pituitary gland and craniopharyngeal duct (pouch)
|
Neoplasms | 1 | 0.887 – 1.13 | 0.974 | 314 | 2862 | exclusion | phecode |
| 228 | Hemangioma and lymphangioma, any site | Neoplasms | 0.973 | 0.92 – 1.03 | 0.334 | 1426 | 13196 | exclusion | phecode |
| 228.1 | Hemangioma of skin and subcutaneous tissue | Neoplasms | 0.984 | 0.916 – 1.06 | 0.652 | 881 | 8094 | exclusion | phecode |
| 229 | Benign neoplasm of unspecified sites | Neoplasms | 0.999 | 0.968 – 1.03 | 0.928 | 4956 | 24559 | exclusion | phecode |
| 229.1 | Benign neoplasm of lymph nodes | Neoplasms | 1.01 | 0.973 – 1.05 | 0.642 | 3573 | 22661 | exclusion | phecode |
| 240 | Simple and unspecified goiter | Endocrine/metabolic | 1.04 | 0.959 – 1.12 | 0.358 | 728 | 6673 | exclusion | phecode |
| 241 | Nontoxic nodular goiter | Endocrine/metabolic | 0.983 | 0.936 – 1.03 | 0.477 | 1950 | 14982 | exclusion | phecode |
| 241.1 | Nontoxic uninodular goiter | Endocrine/metabolic | 0.961 | 0.91 – 1.01 | 0.153 | 1519 | 13323 | exclusion | phecode |
| 241.2 | Nontoxic multinodular goiter | Endocrine/metabolic | 0.985 | 0.917 – 1.06 | 0.67 | 889 | 8352 | exclusion | phecode |
| 242 | Thyrotoxicosis with or without goiter | Endocrine/metabolic | 0.978 | 0.911 – 1.05 | 0.536 | 894 | 8906 | exclusion | phecode |
| 242.1 | Graves' disease | Endocrine/metabolic | 1.14 | 1.01 – 1.28 | 0.0276 | 344 | 3478 | exclusion | phecode |
| 242.2 | Toxic multinodular goiter | Endocrine/metabolic | 0.759 | 0.598 – 0.963 | 0.0234 | 77 | 842 | exclusion | phecode |
| 242.3 | Exophthalmos | Endocrine/metabolic | 0.963 | 0.832 – 1.11 | 0.614 | 202 | 1954 | exclusion | phecode |
| 242.31 | Thyrotoxic exophthalmos | Endocrine/metabolic | 1.15 | 0.936 – 1.42 | 0.182 | 100 | 1002 | exclusion | phecode |
| 244 | Hypothyroidism | Endocrine/metabolic | 0.999 | 0.968 – 1.03 | 0.965 | 5224 | 21859 | exclusion | phecode |
| 244.1 | Secondary hypothyroidism | Endocrine/metabolic | 0.978 | 0.92 – 1.04 | 0.484 | 1177 | 11638 | exclusion | phecode |
| 244.2 | Acquired hypothyroidism | Endocrine/metabolic | 1 | 0.932 – 1.08 | 0.937 | 839 | 8069 | exclusion | phecode |
| 244.4 | Hypothyroidism NOS | Endocrine/metabolic | 0.998 | 0.966 – 1.03 | 0.926 | 4852 | 21473 | exclusion | phecode |
| 245 | Thyroiditis | Endocrine/metabolic | 1.01 | 0.927 – 1.1 | 0.803 | 588 | 5607 | exclusion | phecode |
| 245.2 | Chronic thyroiditis | Endocrine/metabolic | 0.986 | 0.897 – 1.08 | 0.767 | 488 | 4645 | exclusion | phecode |
| 245.21 | Chronic lymphocytic thyroiditis | Endocrine/metabolic | 0.981 | 0.892 – 1.08 | 0.69 | 485 | 4598 | exclusion | phecode |
| 246 | Other disorders of thyroid | Endocrine/metabolic | 0.979 | 0.944 – 1.01 | 0.239 | 3990 | 19962 | exclusion | phecode |
| 246.2 | Thyroid cyst | Endocrine/metabolic | 1.12 | 0.862 – 1.45 | 0.404 | 67 | 603 | exclusion | phecode |
| 246.7 | Abnormal results of function study of thyroid | Endocrine/metabolic | 0.97 | 0.891 – 1.06 | 0.486 | 600 | 5828 | exclusion | phecode |
| 249 | Secondary diabetes mellitus | Endocrine/metabolic | 0.983 | 0.897 – 1.08 | 0.713 | 697 | 5215 | exclusion | phecode |
| 250 | Diabetes mellitus | Endocrine/metabolic | 1.03 | 1 – 1.06 | 0.0401 | 8502 | 22101 | exclusion | phecode |
| 250.1 | Type 1 diabetes | Endocrine/metabolic | 1.03 | 0.958 – 1.11 | 0.398 | 1602 | 7527 | exclusion | phecode |
| 250.11 | Type 1 diabetes with ketoacidosis | Endocrine/metabolic | 0.937 | 0.762 – 1.15 | 0.538 | 199 | 702 | exclusion | phecode |
| 250.12 | Type 1 diabetes with renal manifestations | Endocrine/metabolic | 1.06 | 0.918 – 1.22 | 0.426 | 373 | 1765 | exclusion | phecode |
| 250.13 | Type 1 diabetes with ophthalmic manifestations | Endocrine/metabolic | 0.938 | 0.819 – 1.07 | 0.353 | 551 | 2019 | exclusion | phecode |
| 250.14 | Type 1 diabetes with neurological manifestations | Endocrine/metabolic | 1.06 | 0.917 – 1.22 | 0.436 | 425 | 1774 | exclusion | phecode |
| 250.15 |
Diabetes type 1 with peripheral circulatoryDiabetes type 1 with peripheral circulatory disorders
|
Endocrine/metabolic | 0.987 | 0.76 – 1.28 | 0.923 | 94 | 544 | exclusion | phecode |
| 250.2 | Type 2 diabetes | Endocrine/metabolic | 1.05 | 1.01 – 1.08 | 0.00807 | 5870 | 20182 | exclusion | phecode |
| 250.21 | Type 2 diabetes with ketoacidosis | Endocrine/metabolic | 1.08 | 0.885 – 1.32 | 0.452 | 188 | 878 | exclusion | phecode |
| 250.22 | Type 2 diabetes with renal manifestations | Endocrine/metabolic | 1.03 | 0.953 – 1.1 | 0.492 | 1113 | 8138 | exclusion | phecode |
| 250.23 | Type 2 diabetes with ophthalmic manifestations | Endocrine/metabolic | 1.05 | 0.965 – 1.15 | 0.248 | 1013 | 5931 | exclusion | phecode |
| 250.24 | Type 2 diabetes with neurological manifestations | Endocrine/metabolic | 1.09 | 1.02 – 1.17 | 0.00828 | 1500 | 10205 | exclusion | phecode |
| 250.25 |
Diabetes type 2 with peripheral circulatoryDiabetes type 2 with peripheral circulatory disorders
|
Endocrine/metabolic | 1.06 | 0.945 – 1.19 | 0.324 | 456 | 3558 | exclusion | phecode |
| 250.3 | Insulin pump user | Endocrine/metabolic | 1.07 | 1.01 – 1.13 | 0.0276 | 2181 | 13381 | exclusion | phecode |
| 250.4 | Abnormal glucose | Endocrine/metabolic | 1.01 | 0.974 – 1.04 | 0.65 | 5343 | 21052 | exclusion | phecode |
| 250.41 | Impaired fasting glucose | Endocrine/metabolic | 0.974 | 0.912 – 1.04 | 0.442 | 1146 | 10099 | exclusion | phecode |
| 250.42 | Other abnormal glucose | Endocrine/metabolic | 1.01 | 0.975 – 1.05 | 0.573 | 4827 | 20557 | exclusion | phecode |
| 250.5 | Glycosuria or Acetonuria | Endocrine/metabolic | 1.23 | 0.973 – 1.56 | 0.0837 | 97 | 758 | exclusion | phecode |
| 250.6 | Polyneuropathy in diabetes | Endocrine/metabolic | 1.07 | 0.991 – 1.15 | 0.0872 | 1263 | 8155 | exclusion | phecode |
| 250.7 | Diabetic retinopathy | Endocrine/metabolic | 1.02 | 0.953 – 1.1 | 0.515 | 1068 | 6432 | exclusion | phecode |
| 251 | Other disorders of pancreatic internal secretion | Endocrine/metabolic | 1.05 | 0.966 – 1.14 | 0.255 | 667 | 5573 | exclusion | phecode |
| 251.1 | Hypoglycemia | Endocrine/metabolic | 1.09 | 1 – 1.18 | 0.0505 | 840 | 5710 | exclusion | phecode |
| 252 | Disorders of parathyroid gland | Endocrine/metabolic | 0.985 | 0.932 – 1.04 | 0.589 | 1475 | 14482 | exclusion | phecode |
| 252.1 | Hyperparathyroidism | Endocrine/metabolic | 0.984 | 0.928 – 1.04 | 0.574 | 1347 | 13280 | exclusion | phecode |
| 252.2 | Hypoparathyroidism | Endocrine/metabolic | 1.01 | 0.901 – 1.13 | 0.853 | 328 | 3415 | exclusion | phecode |
| 253 |
Disorders of the pituitary gland and itsDisorders of the pituitary gland and its hypothalamic control
|
Endocrine/metabolic | 1.1 | 1.01 – 1.19 | 0.0358 | 610 | 5687 | exclusion | phecode |
| 253.1 | Pituitary hyperfunction | Endocrine/metabolic | 1.09 | 0.935 – 1.26 | 0.279 | 197 | 1833 | exclusion | phecode |
| 253.11 | Acromegaly and gigantism | Endocrine/metabolic | 1.04 | 0.785 – 1.37 | 0.798 | 61 | 587 | exclusion | phecode |
| 253.2 | Pituitary hypofunction | Endocrine/metabolic | 1.07 | 0.904 – 1.26 | 0.439 | 153 | 1461 | exclusion | phecode |
| 253.3 | Diabetes insipidus | Endocrine/metabolic | 1.27 | 0.976 – 1.65 | 0.0753 | 61 | 606 | exclusion | phecode |
| 253.4 | Anterior pituitary disorders | Endocrine/metabolic | 0.873 | 0.7 – 1.09 | 0.23 | 88 | 799 | exclusion | phecode |
| 253.7 | Other disorders of neurohypophysis | Endocrine/metabolic | 1.01 | 0.781 – 1.29 | 0.968 | 69 | 650 | exclusion | phecode |
| 255 | Disorders of adrenal glands | Endocrine/metabolic | 1.02 | 0.954 – 1.09 | 0.564 | 1017 | 9782 | exclusion | phecode |
| 255.1 | Adrenal hyperfunction | Endocrine/metabolic | 0.913 | 0.804 – 1.04 | 0.16 | 278 | 2562 | exclusion | phecode |
| 255.11 | Cushing's syndrome | Endocrine/metabolic | 0.885 | 0.738 – 1.06 | 0.187 | 138 | 1285 | exclusion | phecode |
| 255.12 | Hyperaldosteronism | Endocrine/metabolic | 0.847 | 0.68 – 1.05 | 0.138 | 94 | 882 | exclusion | phecode |
| 255.2 | Adrenal hypofunction | Endocrine/metabolic | 1.07 | 0.963 – 1.18 | 0.212 | 426 | 4198 | exclusion | phecode |
| 255.21 | Glucocorticoid deficiency | Endocrine/metabolic | 1.09 | 0.983 – 1.21 | 0.102 | 402 | 4000 | exclusion | phecode |
| 256 | Ovarian dysfunction | Endocrine/metabolic | 0.978 | 0.911 – 1.05 | 0.532 | 907 | 8045 | exclusion | phecode |
| 256.4 | Polycystic ovaries | Endocrine/metabolic | 1.04 | 0.958 – 1.13 | 0.336 | 602 | 5604 | exclusion | phecode |
| 257 | Testicular dysfunction | Endocrine/metabolic | 0.974 | 0.895 – 1.06 | 0.55 | 624 | 5557 | exclusion | phecode |
| 257.1 | Testicular hypofunction | Endocrine/metabolic | 0.973 | 0.893 – 1.06 | 0.538 | 604 | 5332 | exclusion | phecode |
| 258 | Iatrogenic endocrine disorders | Endocrine/metabolic | 1.11 | 0.861 – 1.44 | 0.412 | 58 | 606 | exclusion | phecode |
| 258.1 | Postablative ovarian failure | Endocrine/metabolic | 0.731 | 0.579 – 0.922 | 0.00828 | 87 | 821 | exclusion | phecode |
| 259 | Other endocrine disorders | Endocrine/metabolic | 0.943 | 0.872 – 1.02 | 0.148 | 710 | 6901 | exclusion | phecode |
| 260 | Protein-calorie malnutrition | Endocrine/metabolic | 1.08 | 1.03 – 1.14 | 0.00271 | 1748 | 17168 | exclusion | phecode |
| 260.1 | Cachexia | Endocrine/metabolic | 1.13 | 0.97 – 1.32 | 0.114 | 186 | 1826 | exclusion | phecode |
| 260.2 | severe protein-calorie malnutrition | Endocrine/metabolic | 1.12 | 1.05 – 1.2 | 0.00063 | 1022 | 10626 | exclusion | phecode |
| 260.22 | Nutritional marasmus | Endocrine/metabolic | 1.12 | 1.01 – 1.25 | 0.0338 | 380 | 3914 | exclusion | phecode |
| 260.3 | Adult failure to thrive | Endocrine/metabolic | 1.06 | 0.952 – 1.19 | 0.278 | 363 | 3727 | exclusion | phecode |
| 260.6 | Anorexia | Endocrine/metabolic | 1.05 | 0.963 – 1.15 | 0.253 | 551 | 5356 | exclusion | phecode |
| 260.7 | Polyphagia | Endocrine/metabolic | 1.12 | 0.811 – 1.55 | 0.486 | 43 | 462 | exclusion | phecode |
| 261 | Vitamin deficiency | Endocrine/metabolic | 0.989 | 0.958 – 1.02 | 0.483 | 5208 | 23835 | exclusion | phecode |
| 261.1 | Vitamin A deficiency | Endocrine/metabolic | 1.03 | 0.765 – 1.38 | 0.853 | 47 | 486 | exclusion | phecode |
| 261.2 | Vitamin B-complex deficiencies | Endocrine/metabolic | 1.07 | 0.975 – 1.17 | 0.156 | 540 | 5392 | exclusion | phecode |
| 261.4 | Vitamin D deficiency | Endocrine/metabolic | 0.984 | 0.953 – 1.02 | 0.34 | 4931 | 23875 | exclusion | phecode |
| 261.41 | Rickets or osteomalacia | Endocrine/metabolic | 0.838 | 0.596 – 1.18 | 0.307 | 33 | 348 | exclusion | phecode |
| 262 | Mineral deficiency NEC | Endocrine/metabolic | 0.973 | 0.904 – 1.05 | 0.466 | 815 | 7921 | exclusion | phecode |
| 263 | Other nutritional deficiency | Endocrine/metabolic | 1.01 | 0.95 – 1.08 | 0.7 | 1095 | 10465 | exclusion | phecode |
| 264 | Lack of normal physiological development | Endocrine/metabolic | 0.973 | 0.833 – 1.14 | 0.735 | 191 | 1718 | exclusion | phecode |
| 264.2 | Failure to thrive (childhood) | Endocrine/metabolic | 0.989 | 0.792 – 1.24 | 0.923 | 89 | 830 | exclusion | phecode |
| 264.9 |
Lack of normal physiological developmentLack of normal physiological development, unspecified
|
Endocrine/metabolic | 0.873 | 0.676 – 1.13 | 0.298 | 72 | 635 | exclusion | phecode |
| 269 | Proteinuria | Endocrine/metabolic | 1.01 | 0.947 – 1.08 | 0.736 | 1099 | 9025 | exclusion | phecode |
| 270 |
Disorders of protein plasma/amino-acidDisorders of protein plasma/amino-acid transport and metabolism
|
Endocrine/metabolic | 1.1 | 1.01 – 1.19 | 0.0318 | 609 | 5960 | exclusion | phecode |
| 270.1 | Disturbances of amino-acid transport | Endocrine/metabolic | 1.08 | 0.899 – 1.29 | 0.417 | 134 | 1179 | exclusion | phecode |
| 270.11 |
Disturbances of sulphur-bearing amino-acidDisturbances of sulphur-bearing amino-acid metabolism
|
Endocrine/metabolic | 1.09 | 0.892 – 1.33 | 0.407 | 109 | 929 | exclusion | phecode |
| 270.2 | Disorders of amino-acid metabolism | Endocrine/metabolic | 1.14 | 0.88 – 1.46 | 0.329 | 69 | 630 | exclusion | phecode |
| 270.3 | Disorders of plasma protein metabolism | Endocrine/metabolic | 1.11 | 1 – 1.23 | 0.0415 | 432 | 4417 | exclusion | phecode |
| 270.32 | Paraproteinemia | Endocrine/metabolic | 1.12 | 0.965 – 1.29 | 0.139 | 204 | 2115 | exclusion | phecode |
| 270.33 | Amyloidosis | Endocrine/metabolic | 1.31 | 0.963 – 1.79 | 0.0855 | 40 | 412 | exclusion | phecode |
| 270.34 | Alpha-1-antitrypsin deficiency | Endocrine/metabolic | 1.17 | 0.844 – 1.63 | 0.34 | 43 | 468 | exclusion | phecode |
| 270.38 |
Other specified disorders of plasma proteinOther specified disorders of plasma protein metabolism
|
Endocrine/metabolic | 1.1 | 0.949 – 1.26 | 0.215 | 196 | 1937 | exclusion | phecode |
| 271 |
Disorders of carbohydrate transport andDisorders of carbohydrate transport and metabolism
|
Endocrine/metabolic | 0.973 | 0.927 – 1.02 | 0.271 | 1895 | 18044 | exclusion | phecode |
| 271.3 |
Intestinal disaccharidase deficiencies andIntestinal disaccharidase deficiencies and disaccharide malabsorption
|
Endocrine/metabolic | 0.973 | 0.926 – 1.02 | 0.284 | 1838 | 17537 | exclusion | phecode |
| 271.9 |
Other disorders of carbohydrate transport andOther disorders of carbohydrate transport and metabolism
|
Endocrine/metabolic | 0.99 | 0.776 – 1.26 | 0.939 | 71 | 700 | exclusion | phecode |
| 272 | Disorders of lipoid metabolism | Endocrine/metabolic | 1.03 | 1.01 – 1.06 | 0.0174 | 11296 | 19087 | exclusion | phecode |
| 272.1 | Hyperlipidemia | Endocrine/metabolic | 1.03 | 1.01 – 1.06 | 0.0171 | 11268 | 19069 | exclusion | phecode |
| 272.11 | Hypercholesterolemia | Endocrine/metabolic | 1.01 | 0.966 – 1.05 | 0.786 | 3461 | 14855 | exclusion | phecode |
| 272.12 | Hyperglyceridemia | Endocrine/metabolic | 1.06 | 0.981 – 1.14 | 0.146 | 887 | 7838 | exclusion | phecode |
| 272.13 | Mixed hyperlipidemia | Endocrine/metabolic | 1.03 | 0.984 – 1.09 | 0.18 | 2175 | 12371 | exclusion | phecode |
| 272.9 | Unspecified disorder of lipoid metabolism | Endocrine/metabolic | 0.856 | 0.735 – 0.997 | 0.0455 | 193 | 1920 | exclusion | phecode |
| 274 | Gout and other crystal arthropathies | Endocrine/metabolic | 0.984 | 0.93 – 1.04 | 0.575 | 1380 | 13765 | exclusion | phecode |
| 274.1 | Gout | Endocrine/metabolic | 0.982 | 0.927 – 1.04 | 0.552 | 1308 | 13266 | exclusion | phecode |
| 274.11 | Gouty arthropathy | Endocrine/metabolic | 1 | 0.919 – 1.09 | 0.989 | 620 | 6354 | exclusion | phecode |
| 274.2 | Crystal arthropathies | Endocrine/metabolic | 0.916 | 0.748 – 1.12 | 0.398 | 109 | 1065 | exclusion | phecode |
| 274.21 | Chondrocalcinosis | Endocrine/metabolic | 0.91 | 0.736 – 1.12 | 0.381 | 103 | 977 | exclusion | phecode |
| 275 | Disorders of mineral metabolism | Endocrine/metabolic | 1.02 | 0.98 – 1.06 | 0.331 | 2756 | 24347 | exclusion | phecode |
| 275.1 | Disorders of iron metabolism | Hematopoietic | 1.05 | 0.877 – 1.26 | 0.599 | 137 | 1412 | exclusion | phecode |
| 275.11 | Hereditary hemochromatosis | Hematopoietic | 1.16 | 0.888 – 1.51 | 0.281 | 60 | 633 | exclusion | phecode |
| 275.2 | Disorders of copper metabolism | Endocrine/metabolic | 1.05 | 0.782 – 1.4 | 0.764 | 55 | 436 | exclusion | phecode |
| 275.3 | Disorders of magnesium metabolism | Endocrine/metabolic | 1.04 | 0.959 – 1.12 | 0.361 | 711 | 7279 | exclusion | phecode |
| 275.5 | Disorders of calcium/phosphorus metabolism | Endocrine/metabolic | 1 | 0.956 – 1.05 | 0.972 | 2138 | 20564 | exclusion | phecode |
| 275.51 | Hypocalcemia | Endocrine/metabolic | 0.976 | 0.895 – 1.06 | 0.574 | 584 | 5939 | exclusion | phecode |
| 275.53 | Disorders of phosphorus metabolism | Endocrine/metabolic | 1.06 | 0.988 – 1.14 | 0.105 | 853 | 8811 | exclusion | phecode |
| 275.6 | Hypercalcemia | Endocrine/metabolic | 0.945 | 0.883 – 1.01 | 0.108 | 946 | 9235 | exclusion | phecode |
| 276 |
Disorders of fluid, electrolyte, and acid-baseDisorders of fluid, electrolyte, and acid-base balance
|
Endocrine/metabolic | 1.06 | 1.03 – 1.09 | 0.000147 | 5657 | 25433 | exclusion | phecode |
| 276.1 | Electrolyte imbalance | Endocrine/metabolic | 1.05 | 1.01 – 1.09 | 0.0054 | 3839 | 23084 | exclusion | phecode |
| 276.11 | Hyperosmolality and/or hypernatremia | Endocrine/metabolic | 1.19 | 1.05 – 1.34 | 0.00565 | 300 | 3360 | exclusion | phecode |
| 276.12 | Hyposmolality and/or hyponatremia | Endocrine/metabolic | 1.05 | 0.999 – 1.11 | 0.0527 | 1515 | 14642 | exclusion | phecode |
| 276.13 | Hyperpotassemia | Endocrine/metabolic | 1.08 | 1.03 – 1.14 | 0.00205 | 1742 | 16020 | exclusion | phecode |
| 276.14 | Hypopotassemia | Endocrine/metabolic | 1.04 | 0.981 – 1.1 | 0.198 | 1387 | 13660 | exclusion | phecode |
| 276.4 | Acid-base balance disorder | Endocrine/metabolic | 1.13 | 1.07 – 1.2 | 4.07e-05 | 1253 | 13013 | exclusion | phecode |
| 276.41 | Acidosis | Endocrine/metabolic | 1.14 | 1.07 – 1.22 | 4.4e-05 | 1079 | 11280 | exclusion | phecode |
| 276.42 | Alkalosis | Endocrine/metabolic | 1.14 | 1.01 – 1.29 | 0.0411 | 277 | 3023 | exclusion | phecode |
| 276.5 | Hypovolemia | Endocrine/metabolic | 1.08 | 1.04 – 1.12 | 0.000113 | 2892 | 23348 | exclusion | phecode |
| 276.6 | Fluid overload | Endocrine/metabolic | 1.1 | 1.02 – 1.19 | 0.0104 | 761 | 8091 | exclusion | phecode |
| 276.8 | Polydipsia | Endocrine/metabolic | 1 | 0.815 – 1.24 | 0.974 | 102 | 896 | exclusion | phecode |
| 277 | Other disorders of metabolism | Endocrine/metabolic | 0.995 | 0.955 – 1.04 | 0.828 | 2683 | 23261 | exclusion | phecode |
| 277.2 |
Other disorders of purine and pyrimidineOther disorders of purine and pyrimidine metabolism
|
Endocrine/metabolic | 1.02 | 0.892 – 1.17 | 0.768 | 242 | 2462 | exclusion | phecode |
| 277.4 | Disorders of bilirubin excretion | Endocrine/metabolic | 1.06 | 0.964 – 1.17 | 0.218 | 482 | 4579 | exclusion | phecode |
| 277.5 | Other disorders of lipoid metabolism | Endocrine/metabolic | 0.976 | 0.896 – 1.06 | 0.571 | 620 | 6108 | exclusion | phecode |
| 277.51 | Lipoprotein disorders | Endocrine/metabolic | 1.01 | 0.921 – 1.11 | 0.83 | 511 | 5056 | exclusion | phecode |
| 277.7 | Dysmetabolic syndrome X | Endocrine/metabolic | 0.969 | 0.89 – 1.06 | 0.48 | 605 | 5586 | exclusion | phecode |
| 278 | Overweight, obesity and other hyperalimentation | Endocrine/metabolic | 1.06 | 1.04 – 1.09 | 2.03e-07 | 12519 | 18989 | exclusion | phecode |
| 278.1 | Obesity | Endocrine/metabolic | 1.07 | 1.05 – 1.1 | 1.74e-08 | 10920 | 18981 | exclusion | phecode |
| 278.11 | Morbid obesity | Endocrine/metabolic | 1.07 | 1.04 – 1.11 | 8.05e-06 | 5352 | 18858 | exclusion | phecode |
| 278.3 | Localized adiposity | Endocrine/metabolic | 1.13 | 0.983 – 1.3 | 0.0862 | 227 | 2304 | exclusion | phecode |
| 278.4 | Abnormal weight gain | Endocrine/metabolic | 1.05 | 0.995 – 1.11 | 0.0728 | 1491 | 12475 | exclusion | phecode |
| 279 | Disorders involving the immune mechanism | Endocrine/metabolic | 0.989 | 0.942 – 1.04 | 0.663 | 1911 | 19277 | exclusion | phecode |
| 279.1 | Immunity deficiency | Endocrine/metabolic | 0.972 | 0.9 – 1.05 | 0.473 | 752 | 7787 | exclusion | phecode |
| 279.11 | Deficiency of humoral immunity | Endocrine/metabolic | 0.916 | 0.794 – 1.06 | 0.231 | 206 | 2138 | exclusion | phecode |
| 279.2 | Autoimmune disease NEC | Endocrine/metabolic | 1.01 | 0.919 – 1.11 | 0.865 | 528 | 5188 | exclusion | phecode |
| 279.7 | Other immunological findings | Endocrine/metabolic | 1.01 | 0.974 – 1.05 | 0.561 | 3188 | 24267 | exclusion | phecode |
| 279.8 |
Other specified disorders involving the immuneOther specified disorders involving the immune mechanism
|
Endocrine/metabolic | 0.971 | 0.875 – 1.08 | 0.587 | 424 | 4137 | exclusion | phecode |
| 280 | Iron deficiency anemias | Hematopoietic | 1.01 | 0.972 – 1.05 | 0.588 | 2946 | 20825 | exclusion | phecode |
| 280.1 |
Iron deficiency anemias, unspecified or not dueIron deficiency anemias, unspecified or not due to blood loss
|
Hematopoietic | 1.01 | 0.971 – 1.05 | 0.597 | 2860 | 20681 | exclusion | phecode |
| 280.2 |
Iron deficiency anemia secondary to blood lossIron deficiency anemia secondary to blood loss (chronic)
|
Hematopoietic | 0.974 | 0.914 – 1.04 | 0.409 | 1102 | 11204 | exclusion | phecode |
| 281 | Other deficiency anemia | Hematopoietic | 1.18 | 1.05 – 1.32 | 0.00453 | 346 | 3276 | exclusion | phecode |
| 281.1 | Megaloblastic anemia | Hematopoietic | 1.15 | 0.986 – 1.34 | 0.0754 | 177 | 1651 | exclusion | phecode |
| 281.11 | Pernicious anemia | Hematopoietic | 1.12 | 0.89 – 1.41 | 0.33 | 76 | 709 | exclusion | phecode |
| 281.12 | Other vitamin B12 deficiency anemia | Hematopoietic | 1.2 | 1 – 1.43 | 0.0458 | 133 | 1192 | exclusion | phecode |
| 281.9 | Deficiency anemias | Hematopoietic | 1.23 | 1.05 – 1.43 | 0.009 | 188 | 1755 | exclusion | phecode |
| 282 | Hereditary hemolytic anemias | Hematopoietic | 0.884 | 0.765 – 1.02 | 0.098 | 211 | 2051 | exclusion | phecode |
| 282.8 | Other hemoglobinopathies | Hematopoietic | 0.932 | 0.785 – 1.11 | 0.417 | 149 | 1358 | exclusion | phecode |
| 282.9 | Other hereditary hemolytic anemias | Hematopoietic | 0.876 | 0.722 – 1.06 | 0.178 | 119 | 1208 | exclusion | phecode |
| 283 | Acquired hemolytic anemias | Hematopoietic | 0.989 | 0.789 – 1.24 | 0.927 | 83 | 971 | exclusion | phecode |
| 283.1 | Autoimmune hemolytic anemias | Hematopoietic | 1.11 | 0.801 – 1.55 | 0.52 | 34 | 414 | exclusion | phecode |
| 284 | Aplastic anemia | Hematopoietic | 1.06 | 0.96 – 1.18 | 0.237 | 421 | 4488 | exclusion | phecode |
| 284.1 | Pancytopenia | Hematopoietic | 1.04 | 0.932 – 1.16 | 0.488 | 366 | 3929 | exclusion | phecode |
| 285 | Other anemias | Hematopoietic | 1.02 | 0.995 – 1.05 | 0.111 | 7429 | 23103 | exclusion | phecode |
| 285.1 | Acute posthemorrhagic anemia | Hematopoietic | 1.03 | 0.983 – 1.08 | 0.205 | 2008 | 18261 | exclusion | phecode |
| 285.2 | Anemia of chronic disease | Hematopoietic | 1 | 0.945 – 1.06 | 0.914 | 1239 | 12760 | exclusion | phecode |
| 285.21 | Anemia in chronic kidney disease | Hematopoietic | 1.01 | 0.921 – 1.1 | 0.872 | 548 | 5724 | exclusion | phecode |
| 285.22 | Anemia in neoplastic disease | Hematopoietic | 0.964 | 0.873 – 1.07 | 0.476 | 428 | 4452 | exclusion | phecode |
| 286 | Coagulation defects | Hematopoietic | 1.01 | 0.964 – 1.05 | 0.792 | 2429 | 22128 | exclusion | phecode |
| 286.1 | Congenital coagulation defects | Hematopoietic | 0.941 | 0.803 – 1.1 | 0.453 | 173 | 1756 | exclusion | phecode |
| 286.11 | Von willebrand's disease | Hematopoietic | 0.825 | 0.628 – 1.08 | 0.168 | 54 | 567 | exclusion | phecode |
| 286.12 |
Congenital deficiency of other clotting factorsCongenital deficiency of other clotting factors (including factor VII)
|
Hematopoietic | 1.04 | 0.833 – 1.29 | 0.748 | 90 | 898 | exclusion | phecode |
| 286.2 |
Encounter for long-term (current) use ofEncounter for long-term (current) use of anticoagulants
|
Hematopoietic | 1.02 | 0.969 – 1.07 | 0.479 | 1876 | 16443 | exclusion | phecode |
| 286.3 |
Coagulation defects complicating pregnancy orCoagulation defects complicating pregnancy or postpartum
|
Hematopoietic | 1.02 | 0.81 – 1.28 | 0.887 | 81 | 803 | exclusion | phecode |
| 286.4 | Acquired coagulation factor deficiency | Hematopoietic | 0.994 | 0.831 – 1.19 | 0.945 | 148 | 1614 | exclusion | phecode |
| 286.5 |
Hemorrhagic disorder due to intrinsicHemorrhagic disorder due to intrinsic circulating anticoagulants
|
Hematopoietic | 1.09 | 0.842 – 1.41 | 0.516 | 66 | 795 | exclusion | phecode |
| 286.6 | Defibrination syndrome | Hematopoietic | 0.997 | 0.947 – 1.05 | 0.911 | 1655 | 16484 | exclusion | phecode |
| 286.7 | Other and unspecified coagulation defects | Hematopoietic | 1 | 0.954 – 1.05 | 0.986 | 1950 | 19132 | exclusion | phecode |
| 286.8 | Hypercoagulable state | Hematopoietic | 0.919 | 0.842 – 1 | 0.0591 | 576 | 5735 | exclusion | phecode |
| 286.81 | Primary hypercoagulable state | Hematopoietic | 0.936 | 0.856 – 1.02 | 0.143 | 556 | 5506 | exclusion | phecode |
| 286.9 | Abnormal coagulation profile | Hematopoietic | 1.01 | 0.935 – 1.1 | 0.761 | 689 | 7056 | exclusion | phecode |
| 287 | Purpura and other hemorrhagic conditions | Hematopoietic | 0.994 | 0.949 – 1.04 | 0.817 | 2010 | 18524 | exclusion | phecode |
| 287.1 | Spontaneous ecchymoses | Hematopoietic | 1.01 | 0.842 – 1.21 | 0.922 | 139 | 1382 | exclusion | phecode |
| 287.3 | Thrombocytopenia | Hematopoietic | 1.01 | 0.959 – 1.06 | 0.771 | 1790 | 17005 | exclusion | phecode |
| 287.31 | Primary thrombocytopenia | Hematopoietic | 0.978 | 0.878 – 1.09 | 0.688 | 385 | 3763 | exclusion | phecode |
| 287.32 | Secondary thrombocytopenia | Hematopoietic | 0.993 | 0.89 – 1.11 | 0.899 | 356 | 3641 | exclusion | phecode |
| 287.4 | Qualitative platelet defects | Hematopoietic | 0.977 | 0.769 – 1.24 | 0.85 | 79 | 746 | exclusion | phecode |
| 288 | Diseases of white blood cells | Hematopoietic | 1.06 | 1.02 – 1.1 | 0.00238 | 3147 | 24614 | exclusion | phecode |
| 288.1 | Decreased white blood cell count | Hematopoietic | 0.976 | 0.914 – 1.04 | 0.469 | 1022 | 10464 | exclusion | phecode |
| 288.11 | Neutropenia | Hematopoietic | 0.969 | 0.895 – 1.05 | 0.448 | 682 | 7256 | exclusion | phecode |
| 288.2 | Elevated white blood cell count | Hematopoietic | 1.08 | 1.04 – 1.12 | 0.000284 | 2640 | 23395 | exclusion | phecode |
| 288.3 | Eosinophilia | Hematopoietic | 0.854 | 0.714 – 1.02 | 0.0844 | 137 | 1270 | exclusion | phecode |
| 289 | Other diseases of blood and blood-forming organs | Hematopoietic | 0.935 | 0.878 – 0.995 | 0.0343 | 1148 | 11399 | exclusion | phecode |
| 289.3 |
Personal history of diseases of blood andPersonal history of diseases of blood and blood-forming organs
|
Hematopoietic | 0.91 | 0.836 – 0.991 | 0.0304 | 613 | 6157 | exclusion | phecode |
| 289.4 | Lymphadenitis | Hematopoietic | 1.01 | 0.966 – 1.05 | 0.722 | 2511 | 23286 | exclusion | phecode |
| 289.5 | Diseases of spleen | Hematopoietic | 1.01 | 0.889 – 1.15 | 0.853 | 246 | 2566 | exclusion | phecode |
| 289.8 | Polycythemia, secondary | Hematopoietic | 1.03 | 0.88 – 1.22 | 0.679 | 173 | 1631 | exclusion | phecode |
| 289.9 | Abnormality of red blood cells | Hematopoietic | 0.975 | 0.851 – 1.12 | 0.713 | 248 | 2453 | exclusion | phecode |
| 290 |
Delirium dementia and amnestic and otherDelirium dementia and amnestic and other cognitive disorders
|
Mental Disorders | 1.11 | 1.02 – 1.2 | 0.0118 | 715 | 6578 | exclusion | phecode |
| 290.1 | Dementias | Mental Disorders | 0.981 | 0.862 – 1.12 | 0.771 | 264 | 2631 | exclusion | phecode |
| 290.11 | Alzheimer's disease | Mental Disorders | 0.759 | 0.582 – 0.99 | 0.0418 | 64 | 748 | exclusion | phecode |
| 290.12 | Dementia with cerebral degenerations | Mental Disorders | 0.858 | 0.63 – 1.17 | 0.331 | 44 | 440 | exclusion | phecode |
| 290.13 | Senile dementia | Mental Disorders | 0.936 | 0.792 – 1.11 | 0.434 | 162 | 1595 | exclusion | phecode |
| 290.16 | Vascular dementia | Mental Disorders | 1.29 | 0.895 – 1.85 | 0.173 | 38 | 402 | exclusion | phecode |
| 290.2 | Delirium due to conditions classified elsewhere | Mental Disorders | 1.2 | 1.08 – 1.33 | 0.000588 | 432 | 4303 | exclusion | phecode |
| 290.3 |
Other persistent mental disorders due toOther persistent mental disorders due to conditions classified elsewhere
|
Mental Disorders | 0.985 | 0.9 – 1.08 | 0.739 | 559 | 5347 | exclusion | phecode |
| 291 |
Other specified nonpsychotic and/or transientOther specified nonpsychotic and/or transient mental disorders
|
Mental Disorders | 1.05 | 1 – 1.11 | 0.0456 | 1691 | 16570 | exclusion | phecode |
| 291.1 |
Transient mental disorders due to conditionsTransient mental disorders due to conditions classified elsewhere
|
Mental Disorders | 1.07 | 0.897 – 1.29 | 0.44 | 128 | 1299 | exclusion | phecode |
| 291.4 |
Specific nonpsychotic mental disorders due toSpecific nonpsychotic mental disorders due to brain damage
|
Mental Disorders | 1.07 | 0.953 – 1.2 | 0.255 | 329 | 3176 | exclusion | phecode |
| 291.8 | Alteration of consciousness | Mental Disorders | 1.06 | 0.997 – 1.12 | 0.0616 | 1323 | 13079 | exclusion | phecode |
| 292 | Neurological disorders | Mental Disorders | 1.03 | 0.998 – 1.07 | 0.0676 | 3583 | 26029 | exclusion | phecode |
| 292.1 | Aphasia/speech disturbance | Mental Disorders | 1.02 | 0.963 – 1.08 | 0.483 | 1272 | 12577 | exclusion | phecode |
| 292.11 | Aphasia | Mental Disorders | 1.02 | 0.919 – 1.13 | 0.717 | 427 | 4145 | exclusion | phecode |
| 292.12 | Symbolic dysfunction | Mental Disorders | 0.925 | 0.766 – 1.12 | 0.413 | 125 | 1297 | exclusion | phecode |
| 292.2 | Mild cognitive impairment | Mental Disorders | 1.02 | 0.875 – 1.18 | 0.842 | 206 | 2139 | exclusion | phecode |
| 292.3 | Memory loss | Mental Disorders | 1.01 | 0.947 – 1.07 | 0.819 | 1188 | 11374 | exclusion | phecode |
| 292.4 | Altered mental status | Mental Disorders | 1.13 | 1.07 – 1.2 | 1.61e-05 | 1446 | 14182 | exclusion | phecode |
| 292.5 | Transient alteration of awareness | Mental Disorders | 1.13 | 1 – 1.29 | 0.05 | 284 | 2811 | exclusion | phecode |
| 292.6 | Hallucinations | Mental Disorders | 1.05 | 0.877 – 1.25 | 0.62 | 137 | 1398 | exclusion | phecode |
| 293 | Symptoms involving head and neck | Mental Disorders | 0.996 | 0.877 – 1.13 | 0.948 | 270 | 2751 | exclusion | phecode |
| 293.1 |
Swelling, mass, or lump in head and neckSwelling, mass, or lump in head and neck [Space-occupying lesion, intracranial NOS]
|
Mental Disorders | 1.02 | 0.983 – 1.06 | 0.258 | 2903 | 25597 | exclusion | phecode |
| 295 | Schizophrenia and other psychotic disorders | Mental Disorders | 1.18 | 1.08 – 1.3 | 0.00041 | 553 | 5197 | exclusion | phecode |
| 295.1 | Schizophrenia | Mental Disorders | 1.06 | 0.85 – 1.32 | 0.615 | 98 | 932 | exclusion | phecode |
| 295.2 | Paranoid disorders | Mental Disorders | 1.04 | 0.812 – 1.34 | 0.744 | 74 | 716 | exclusion | phecode |
| 295.3 | Psychosis | Mental Disorders | 1.24 | 1.12 – 1.37 | 4.47e-05 | 447 | 4178 | exclusion | phecode |
| 296 | Mood disorders | Mental Disorders | 1.12 | 1.09 – 1.15 | 3.11e-16 | 10450 | 14205 | exclusion | phecode |
| 296.1 | Bipolar | Mental Disorders | 1.21 | 1.13 – 1.3 | 7.76e-08 | 970 | 8191 | exclusion | phecode |
| 296.2 | Depression | Mental Disorders | 1.12 | 1.09 – 1.15 | 1.38e-15 | 10057 | 14202 | exclusion | phecode |
| 296.22 | Major depressive disorder | Mental Disorders | 1.12 | 1.09 – 1.15 | 2.94e-15 | 9418 | 14199 | exclusion | phecode |
| 297 | Suicidal ideation or attempt | Mental Disorders | 1.23 | 1.14 – 1.33 | 3.25e-07 | 759 | 6603 | exclusion | phecode |
| 297.1 | Suicidal ideation | Mental Disorders | 1.25 | 1.14 – 1.37 | 9.17e-07 | 613 | 5363 | exclusion | phecode |
| 297.2 | Suicide or self-inflicted injury | Mental Disorders | 1.18 | 1.02 – 1.36 | 0.0252 | 230 | 1990 | exclusion | phecode |
| 300 | Anxiety disorders | Mental Disorders | 1.1 | 1.07 – 1.13 | 5.78e-13 | 10500 | 14198 | exclusion | phecode |
| 300.1 | Anxiety disorder | Mental Disorders | 1.1 | 1.07 – 1.13 | 7.76e-13 | 9897 | 14202 | exclusion | phecode |
| 300.11 | Generalized anxiety disorder | Mental Disorders | 1.09 | 1.05 – 1.13 | 1.47e-05 | 3873 | 13907 | exclusion | phecode |
| 300.12 | Agorophobia, social phobia, and panic disorder | Mental Disorders | 1.17 | 1.09 – 1.25 | 1.53e-05 | 1015 | 8198 | exclusion | phecode |
| 300.13 | Phobia | Mental Disorders | 1.13 | 1.04 – 1.22 | 0.0046 | 714 | 6581 | exclusion | phecode |
| 300.3 | Obsessive-compulsive disorders | Mental Disorders | 0.932 | 0.815 – 1.06 | 0.299 | 255 | 2231 | exclusion | phecode |
| 300.4 | Dysthymic disorder | Mental Disorders | 1.14 | 1.08 – 1.2 | 2.32e-06 | 1676 | 11403 | exclusion | phecode |
| 300.8 | Acute reaction to stress | Mental Disorders | 1.04 | 0.93 – 1.17 | 0.482 | 361 | 3434 | exclusion | phecode |
| 300.9 | Posttraumatic stress disorder | Mental Disorders | 1.27 | 1.16 – 1.38 | 9.2e-08 | 620 | 5794 | exclusion | phecode |
| 301 | Personality disorders | Mental Disorders | 1.3 | 1.16 – 1.46 | 6.85e-06 | 365 | 3354 | exclusion | phecode |
| 301.2 | Antisocial/borderline personality disorder | Mental Disorders | 1.18 | 1.01 – 1.38 | 0.0341 | 201 | 1788 | exclusion | phecode |
| 302 | Sexual and gender identity disorders | Mental Disorders | 0.992 | 0.944 – 1.04 | 0.737 | 2271 | 8980 | exclusion | phecode |
| 302.1 | Decreased libido | Mental Disorders | 1.01 | 0.891 – 1.14 | 0.895 | 304 | 2931 | exclusion | phecode |
| 303 | Psychogenic and somatoform disorders | Mental Disorders | 0.986 | 0.952 – 1.02 | 0.433 | 4471 | 13444 | exclusion | phecode |
| 303.1 | Dissociative disorder | Mental Disorders | 1.08 | 0.894 – 1.31 | 0.419 | 123 | 1129 | exclusion | phecode |
| 303.3 | Psychogenic disorder | Mental Disorders | 0.976 | 0.941 – 1.01 | 0.194 | 4222 | 13305 | exclusion | phecode |
| 303.31 |
Gastrointestinal malfunction arising fromGastrointestinal malfunction arising from mental factors
|
Mental Disorders | 1.07 | 0.955 – 1.21 | 0.237 | 326 | 3152 | exclusion | phecode |
| 303.4 | Somatoform disorder | Mental Disorders | 1.04 | 0.969 – 1.12 | 0.267 | 861 | 7992 | exclusion | phecode |
| 304 | Adjustment reaction | Mental Disorders | 1.12 | 1.08 – 1.17 | 1.53e-07 | 2644 | 13849 | exclusion | phecode |
| 305.2 | Eating disorder | Mental Disorders | 1.15 | 1.06 – 1.25 | 0.000767 | 647 | 6118 | exclusion | phecode |
| 306 | Other mental disorder | Mental Disorders | 1.12 | 1.06 – 1.19 | 0.000158 | 1279 | 9950 | exclusion | phecode |
| 306.1 | Mental disorders durring/after pregnancy | Mental Disorders | 1.16 | 1.04 – 1.28 | 0.00534 | 475 | 2847 | exclusion | phecode |
| 306.9 | Tension headache | Mental Disorders | 1.16 | 1.06 – 1.27 | 0.00128 | 554 | 5305 | exclusion | phecode |
| 312 | Conduct disorders | Mental Disorders | 1.17 | 1.01 – 1.37 | 0.0414 | 184 | 1746 | exclusion | phecode |
| 312.3 | Impulse control disorder | Mental Disorders | 1.27 | 0.969 – 1.67 | 0.0834 | 58 | 529 | exclusion | phecode |
| 313 | Pervasive developmental disorders | Mental Disorders | 1.04 | 0.98 – 1.11 | 0.192 | 1202 | 11236 | exclusion | phecode |
| 313.1 | Attention deficit hyperactivity disorder | Mental Disorders | 1.04 | 0.972 – 1.11 | 0.268 | 1073 | 10245 | exclusion | phecode |
| 313.2 | Tics and stuttering | Mental Disorders | 1.43 | 1.07 – 1.89 | 0.014 | 55 | 548 | exclusion | phecode |
| 313.3 | Autism | Mental Disorders | 1.26 | 0.954 – 1.67 | 0.103 | 56 | 505 | exclusion | phecode |
| 315 | Develomental delays and disorders | Mental Disorders | 1 | 0.909 – 1.1 | 0.963 | 461 | 4493 | exclusion | phecode |
| 315.1 | Learning disorder | Mental Disorders | 0.9 | 0.698 – 1.16 | 0.419 | 70 | 685 | exclusion | phecode |
| 315.2 | Speech and language disorder | Mental Disorders | 0.904 | 0.771 – 1.06 | 0.213 | 180 | 1687 | exclusion | phecode |
| 316 | Substance addiction and disorders | Mental Disorders | 1.3 | 1.25 – 1.36 | 1.9e-34 | 2546 | 22655 | exclusion | phecode |
| 316.1 | Polyneuropathy due to drugs | Mental Disorders | 1.08 | 0.971 – 1.19 | 0.161 | 416 | 4278 | exclusion | phecode |
| 317 | Alcohol-related disorders | Mental Disorders | 1.3 | 1.24 – 1.37 | 1.07e-22 | 1645 | 15463 | exclusion | phecode |
| 317.1 | Alcoholism | Mental Disorders | 1.27 | 1.2 – 1.35 | 4.56e-16 | 1338 | 12990 | exclusion | phecode |
| 317.11 | Alcoholic liver damage | Mental Disorders | 1.24 | 1.09 – 1.41 | 0.00131 | 269 | 2677 | exclusion | phecode |
| 318 | Tobacco use disorder | Mental Disorders | 1.48 | 1.44 – 1.53 | 2.73e-130 | 5189 | 24143 | exclusion | phecode |
| 320 | Meningitis | Neurological | 1.04 | 0.913 – 1.18 | 0.562 | 255 | 2598 | exclusion | phecode |
| 323 | Encephalitis | Neurological | 1.12 | 0.939 – 1.35 | 0.203 | 133 | 1225 | exclusion | phecode |
| 323.8 | Encephalitis, non-infectious | Neurological | 1.1 | 0.9 – 1.33 | 0.363 | 111 | 1018 | exclusion | phecode |
| 324 | Other CNS infection and poliomyelitis | Neurological | 1.14 | 0.971 – 1.33 | 0.11 | 182 | 1730 | exclusion | phecode |
| 325 |
Phlebitis and thrombophlebitis of intracranialPhlebitis and thrombophlebitis of intracranial venous sinuses
|
Neurological | 1.22 | 0.851 – 1.76 | 0.275 | 33 | 349 | exclusion | phecode |
| 327 | Sleep disorders | Neurological | 1.05 | 1.02 – 1.07 | 0.000344 | 9509 | 21852 | exclusion | phecode |
| 327.1 | Hypersomnia | Neurological | 0.974 | 0.92 – 1.03 | 0.358 | 1425 | 13154 | exclusion | phecode |
| 327.3 | Sleep apnea | Neurological | 1.05 | 1.02 – 1.08 | 0.000477 | 6767 | 21562 | exclusion | phecode |
| 327.31 | Central/nonobstroctive sleep apnea | Neurological | 1.03 | 0.914 – 1.16 | 0.618 | 299 | 3056 | exclusion | phecode |
| 327.32 | Obstructive sleep apnea | Neurological | 1.04 | 1 – 1.07 | 0.0274 | 5408 | 20839 | exclusion | phecode |
| 327.4 | Insomnia | Neurological | 1.07 | 1.03 – 1.11 | 0.000192 | 3632 | 21261 | exclusion | phecode |
| 327.41 | Organic or persistent insomnia | Neurological | 1.04 | 0.964 – 1.12 | 0.327 | 844 | 8171 | exclusion | phecode |
| 327.5 | Parasomnia | Neurological | 1.03 | 0.926 – 1.15 | 0.576 | 373 | 3846 | exclusion | phecode |
| 327.6 | Circadian rhythm sleep disorder | Neurological | 1.05 | 0.904 – 1.22 | 0.511 | 196 | 1905 | exclusion | phecode |
| 327.7 | Sleep related movement disorders | Neurological | 1.06 | 0.995 – 1.13 | 0.0711 | 1145 | 11408 | exclusion | phecode |
| 327.71 | Restless legs syndrome | Neurological | 1.06 | 0.992 – 1.13 | 0.0852 | 996 | 10139 | exclusion | phecode |
| 327.72 | Sleep related leg cramps | Neurological | 1.04 | 0.783 – 1.39 | 0.771 | 56 | 509 | exclusion | phecode |
| 331 | Other cerebral degenerations | Neurological | 1.1 | 0.991 – 1.22 | 0.075 | 432 | 4236 | exclusion | phecode |
| 331.1 | Hydrocephalus | Neurological | 1.06 | 0.905 – 1.23 | 0.493 | 191 | 1886 | exclusion | phecode |
| 331.9 | Cerebral degeneration, unspecified | Neurological | 1.09 | 0.944 – 1.25 | 0.246 | 233 | 2291 | exclusion | phecode |
| 332 | Parkinson's disease | Neurological | 0.963 | 0.845 – 1.1 | 0.569 | 259 | 2213 | exclusion | phecode |
| 333 |
Extrapyramidal disease and abnormal movementExtrapyramidal disease and abnormal movement disorders
|
Neurological | 1.05 | 0.997 – 1.1 | 0.0657 | 1827 | 17161 | exclusion | phecode |
| 333.1 | Essential tremor | Neurological | 0.97 | 0.877 – 1.07 | 0.552 | 445 | 4217 | exclusion | phecode |
| 333.2 | Myoclonus | Neurological | 1.02 | 0.823 – 1.27 | 0.834 | 88 | 1039 | exclusion | phecode |
| 333.4 | Torsion dystonia | Neurological | 0.996 | 0.869 – 1.14 | 0.96 | 237 | 2316 | exclusion | phecode |
| 333.8 | Other degenerative diseases of the basal ganglia | Neurological | 1.07 | 0.799 – 1.42 | 0.659 | 52 | 536 | exclusion | phecode |
| 334 | Degenerative disease of the spinal cord | Neurological | 1.05 | 0.968 – 1.14 | 0.241 | 674 | 6761 | exclusion | phecode |
| 334.1 | Spinocerebellar disease | Neurological | 0.952 | 0.708 – 1.28 | 0.744 | 53 | 504 | exclusion | phecode |
| 334.2 | Anterior horn cell disease | Neurological | 0.827 | 0.639 – 1.07 | 0.148 | 66 | 687 | exclusion | phecode |
| 334.21 | Amyotrophic Lateral Sclerosis | Neurological | 1.02 | 0.733 – 1.41 | 0.927 | 43 | 437 | exclusion | phecode |
| 335 | Multiple sclerosis | Neurological | 1.06 | 0.925 – 1.2 | 0.422 | 252 | 2694 | exclusion | phecode |
| 337 | Disorders of the autonomic nervous system | Neurological | 0.948 | 0.864 – 1.04 | 0.26 | 531 | 4946 | exclusion | phecode |
| 337.1 | Peripheral autonomic neuropathy | Neurological | 0.875 | 0.761 – 1.01 | 0.0612 | 227 | 1995 | exclusion | phecode |
| 338 | Pain | Neurological | 1.07 | 1.05 – 1.1 | 6.97e-09 | 13666 | 17853 | exclusion | phecode |
| 338.1 | Acute pain | Neurological | 1.08 | 1.05 – 1.1 | 1.33e-08 | 10419 | 17761 | exclusion | phecode |
| 338.2 | Chronic pain | Neurological | 1.1 | 1.07 – 1.13 | 3.93e-11 | 7334 | 17807 | exclusion | phecode |
| 339 | Other headache syndromes | Neurological | 1.07 | 1.04 – 1.1 | 6e-06 | 6604 | 22880 | exclusion | phecode |
| 340 | Migraine | Neurological | 1.03 | 1 – 1.07 | 0.0524 | 4866 | 20786 | exclusion | phecode |
| 340.1 | Migrain with aura | Neurological | 1.03 | 0.988 – 1.08 | 0.164 | 2628 | 16321 | exclusion | phecode |
| 341 |
Other demyelinating diseases of central nervousOther demyelinating diseases of central nervous system
|
Neurological | 1.01 | 0.799 – 1.27 | 0.958 | 84 | 918 | exclusion | phecode |
| 342 | Hemiplegia | Neurological | 1.08 | 0.959 – 1.22 | 0.207 | 317 | 2976 | exclusion | phecode |
| 343 | Infantile cerebral palsy | Neurological | 1.06 | 0.823 – 1.37 | 0.646 | 68 | 658 | exclusion | phecode |
| 344 | Other paralytic syndromes | Neurological | 1.08 | 0.975 – 1.2 | 0.139 | 435 | 4489 | exclusion | phecode |
| 345 | Epilepsy, recurrent seizures, convulsions | Neurological | 1.08 | 1.03 – 1.14 | 0.00237 | 1767 | 17304 | exclusion | phecode |
| 345.1 | Epilepsy | Neurological | 1.05 | 0.955 – 1.15 | 0.324 | 512 | 5188 | exclusion | phecode |
| 345.11 | Generalized convulsive epilepsy | Neurological | 1.06 | 0.9 – 1.25 | 0.486 | 165 | 1700 | exclusion | phecode |
| 345.12 | Partial epilepsy | Neurological | 1.05 | 0.937 – 1.17 | 0.427 | 364 | 3719 | exclusion | phecode |
| 345.3 | Convulsions | Neurological | 1.09 | 1.03 – 1.14 | 0.00165 | 1667 | 16296 | exclusion | phecode |
| 346 |
Abnormal findings on study of brain and/orAbnormal findings on study of brain and/or nervous system
|
Neurological | 1.11 | 0.921 – 1.34 | 0.271 | 118 | 1199 | exclusion | phecode |
| 346.1 |
Nonspecific abnormal findings on radiologicalNonspecific abnormal findings on radiological and other examination of skull and head
|
Neurological | 1.08 | 1 – 1.15 | 0.0406 | 914 | 9277 | exclusion | phecode |
| 346.2 |
Nonspecific abnormal results of function studyNonspecific abnormal results of function study of brain and central nervous system
|
Neurological | 1.16 | 0.914 – 1.47 | 0.223 | 75 | 793 | exclusion | phecode |
| 346.3 |
Nonspecific abnormal findings in cerebrospinalNonspecific abnormal findings in cerebrospinal fluid
|
Neurological | 1.35 | 1.05 – 1.74 | 0.0214 | 72 | 747 | exclusion | phecode |
| 347 | Cataplexy and narcolepsy | Neurological | 0.961 | 0.76 – 1.22 | 0.741 | 78 | 730 | exclusion | phecode |
| 348 | Other conditions of brain | Neurological | 1.1 | 1.03 – 1.17 | 0.00301 | 1219 | 11888 | exclusion | phecode |
| 348.2 | Cerebral edema and compression of brain | Neurological | 1.05 | 0.968 – 1.14 | 0.229 | 642 | 6113 | exclusion | phecode |
| 348.4 | Cerebral cysts | Neurological | 0.895 | 0.759 – 1.05 | 0.184 | 168 | 1620 | exclusion | phecode |
| 348.7 | Coma | Neurological | 1.02 | 0.864 – 1.2 | 0.816 | 163 | 1511 | exclusion | phecode |
| 348.8 | Encephalopathy, not elsewhere classified | Neurological | 1.22 | 1.11 – 1.33 | 2.17e-05 | 546 | 5352 | exclusion | phecode |
| 348.9 | Other conditions of brain, NOS | Neurological | 1.05 | 0.992 – 1.1 | 0.0935 | 1534 | 15257 | exclusion | phecode |
| 349 |
Other and unspecified disorders of the nervousOther and unspecified disorders of the nervous system
|
Neurological | 1.09 | 1 – 1.18 | 0.0487 | 625 | 6279 | exclusion | phecode |
| 350 | Abnormal movement | Neurological | 1.01 | 0.975 – 1.04 | 0.63 | 4286 | 26182 | exclusion | phecode |
| 350.1 | Abnormal involuntary movements | Neurological | 0.994 | 0.95 – 1.04 | 0.804 | 2132 | 19795 | exclusion | phecode |
| 350.2 | Abnormality of gait | Neurological | 1.03 | 0.984 – 1.07 | 0.224 | 2406 | 19507 | exclusion | phecode |
| 350.3 | Lack of coordination | Neurological | 1.06 | 0.979 – 1.15 | 0.151 | 700 | 6867 | exclusion | phecode |
| 350.5 | Abnormal reflex | Neurological | 0.954 | 0.799 – 1.14 | 0.602 | 130 | 1314 | exclusion | phecode |
| 350.6 | Disturbances of sensation of smell and taste | Neurological | 1 | 0.892 – 1.12 | 0.981 | 332 | 3483 | exclusion | phecode |
| 351 | Other peripheral nerve disorders | Neurological | 1.07 | 1.04 – 1.11 | 2.5e-05 | 4863 | 23119 | exclusion | phecode |
| 352 | Disorders of other cranial nerves | Neurological | 0.995 | 0.935 – 1.06 | 0.877 | 1140 | 11078 | exclusion | phecode |
| 352.1 | Trigeminal nerve disorders [CN5] | Neurological | 1.05 | 0.94 – 1.18 | 0.38 | 342 | 3512 | exclusion | phecode |
| 352.2 | Facial nerve disorders [CN7] | Neurological | 0.95 | 0.866 – 1.04 | 0.278 | 511 | 4990 | exclusion | phecode |
| 353 | Nerve root and plexus disorders | Neurological | 1.11 | 1.07 – 1.16 | 3.55e-07 | 2818 | 22142 | exclusion | phecode |
| 353.1 | Nerve plexus lesions | Neurological | 1.05 | 0.926 – 1.19 | 0.448 | 273 | 2645 | exclusion | phecode |
| 353.2 | Nerve root lesions | Neurological | 1.35 | 1.06 – 1.71 | 0.0164 | 68 | 799 | exclusion | phecode |
| 355 | Complex regional/central pain syndrome | Neurological | 1.05 | 0.941 – 1.17 | 0.376 | 362 | 3674 | exclusion | phecode |
| 355.1 | Chronic pain syndrome | Neurological | 1.17 | 1.08 – 1.28 | 0.000281 | 610 | 5708 | exclusion | phecode |
| 356 | Hereditary and idiopathic peripheral neuropathy | Neurological | 1.05 | 0.992 – 1.11 | 0.0893 | 1426 | 12800 | exclusion | phecode |
| 357 | Inflammatory and toxic neuropathy | Neurological | 1.05 | 1 – 1.1 | 0.0342 | 2140 | 18871 | exclusion | phecode |
| 358 | Myoneural disorders | Neurological | 1.09 | 1.01 – 1.18 | 0.0276 | 720 | 7454 | exclusion | phecode |
| 358.1 | Myasthenia gravis | Neurological | 1.1 | 0.846 – 1.43 | 0.481 | 62 | 663 | exclusion | phecode |
| 359 | Muscular dystrophies and other myopathies | Neurological | 1.07 | 0.993 – 1.16 | 0.0742 | 768 | 7285 | exclusion | phecode |
| 359.1 | Muscular dystrophies | Neurological | 1.15 | 0.831 – 1.6 | 0.393 | 42 | 435 | exclusion | phecode |
| 359.2 | Myopathy | Neurological | 1.07 | 0.99 – 1.16 | 0.0878 | 743 | 7004 | exclusion | phecode |
| 360 | Disorders of the globe | Sense Organs | 0.918 | 0.728 – 1.16 | 0.474 | 85 | 816 | exclusion | phecode |
| 360.2 | Progressive myopia | Sense Organs | 0.738 | 0.542 – 1 | 0.053 | 45 | 422 | exclusion | phecode |
| 361 | Retinal detachments and defects | Sense Organs | 0.935 | 0.844 – 1.04 | 0.195 | 436 | 4266 | exclusion | phecode |
| 361.1 | Retinal detachment with retinal defect | Sense Organs | 0.926 | 0.787 – 1.09 | 0.355 | 166 | 1748 | exclusion | phecode |
| 362 | Other retinal disorders | Sense Organs | 0.963 | 0.918 – 1.01 | 0.133 | 2068 | 14026 | exclusion | phecode |
| 362.2 |
Degeneration of macula and posterior pole ofDegeneration of macula and posterior pole of retina
|
Sense Organs | 1 | 0.941 – 1.07 | 0.948 | 1201 | 8925 | exclusion | phecode |
| 362.21 | Macular degeneration, dry | Sense Organs | 0.974 | 0.836 – 1.14 | 0.736 | 187 | 1782 | exclusion | phecode |
| 362.22 | Macular degeneration, wet | Sense Organs | 0.876 | 0.678 – 1.13 | 0.311 | 70 | 606 | exclusion | phecode |
| 362.23 | Cystoid macular degeneration of retina | Sense Organs | 0.978 | 0.851 – 1.13 | 0.759 | 234 | 2219 | exclusion | phecode |
| 362.26 | Macular puckering of retina | Sense Organs | 0.99 | 0.903 – 1.09 | 0.833 | 543 | 4822 | exclusion | phecode |
| 362.27 | Drusen (degenerative) of retina | Sense Organs | 0.982 | 0.864 – 1.12 | 0.785 | 269 | 2632 | exclusion | phecode |
| 362.29 | Macular degeneration (senile) of retina NOS | Sense Organs | 1.03 | 0.963 – 1.1 | 0.393 | 1040 | 7943 | exclusion | phecode |
| 362.3 | Other nondiabetic retinopathy | Sense Organs | 0.946 | 0.866 – 1.03 | 0.225 | 574 | 5062 | exclusion | phecode |
| 362.31 | Separation of retinal layers | Sense Organs | 0.925 | 0.805 – 1.06 | 0.272 | 231 | 2408 | exclusion | phecode |
| 362.4 | Retinal vascular changes and abnomalities | Sense Organs | 0.904 | 0.81 – 1.01 | 0.0723 | 378 | 3462 | exclusion | phecode |
| 362.6 | Peripheral retinal degenerations | Sense Organs | 0.961 | 0.839 – 1.1 | 0.566 | 238 | 2378 | exclusion | phecode |
| 362.7 | Hereditary retinal dystrophies | Sense Organs | 0.932 | 0.778 – 1.12 | 0.443 | 137 | 1298 | exclusion | phecode |
| 362.8 | Retinal hemorrhage/ischemia | Sense Organs | 1.01 | 0.854 – 1.2 | 0.881 | 156 | 1491 | exclusion | phecode |
| 362.9 | Retinal edema | Sense Organs | 0.883 | 0.754 – 1.03 | 0.122 | 190 | 1731 | exclusion | phecode |
| 363 |
Chorioretinal inflammations, scars, and otherChorioretinal inflammations, scars, and other disorders of choroid
|
Sense Organs | 0.922 | 0.813 – 1.05 | 0.21 | 284 | 2822 | exclusion | phecode |
| 363.3 | Chorioretinal scars | Sense Organs | 0.875 | 0.749 – 1.02 | 0.0927 | 186 | 1892 | exclusion | phecode |
| 364 | Corneal opacity and other disorders of cornea | Sense Organs | 0.927 | 0.858 – 1 | 0.0547 | 750 | 6600 | exclusion | phecode |
| 364.1 | Corneal opacity | Sense Organs | 1.02 | 0.895 – 1.16 | 0.76 | 263 | 2477 | exclusion | phecode |
| 364.2 | Corneal edema | Sense Organs | 0.961 | 0.757 – 1.22 | 0.741 | 81 | 724 | exclusion | phecode |
| 364.4 | Corneal degenerations | Sense Organs | 0.914 | 0.804 – 1.04 | 0.166 | 276 | 2549 | exclusion | phecode |
| 364.41 | Keratoconus | Sense Organs | 0.955 | 0.721 – 1.27 | 0.752 | 59 | 503 | exclusion | phecode |
| 364.5 | Corneal dystrophy | Sense Organs | 0.822 | 0.727 – 0.929 | 0.00172 | 304 | 2702 | exclusion | phecode |
| 364.51 | Fuchs' dystrophy | Sense Organs | 0.775 | 0.657 – 0.915 | 0.0026 | 164 | 1405 | exclusion | phecode |
| 364.9 | Cornea replaced by transplant | Sense Organs | 0.815 | 0.612 – 1.09 | 0.161 | 58 | 492 | exclusion | phecode |
| 365 | Glaucoma | Sense Organs | 0.927 | 0.878 – 0.978 | 0.00567 | 1570 | 12968 | exclusion | phecode |
| 365.1 | Open-angle glaucoma | Sense Organs | 0.897 | 0.81 – 0.992 | 0.0353 | 425 | 3686 | exclusion | phecode |
| 365.11 | Primary open angle glaucoma | Sense Organs | 0.825 | 0.72 – 0.946 | 0.00602 | 230 | 2031 | exclusion | phecode |
| 365.2 | Primary angle-closure glaucoma | Sense Organs | 1.03 | 0.874 – 1.21 | 0.723 | 147 | 1413 | exclusion | phecode |
| 366 | Cataract | Sense Organs | 0.985 | 0.952 – 1.02 | 0.396 | 4990 | 18145 | exclusion | phecode |
| 366.1 | Nonsenile Cataract | Sense Organs | 0.977 | 0.81 – 1.18 | 0.808 | 124 | 1192 | exclusion | phecode |
| 366.2 | Senile cataract | Sense Organs | 0.975 | 0.936 – 1.02 | 0.23 | 3220 | 15763 | exclusion | phecode |
| 367 |
Disorders of refraction and accommodationDisorders of refraction and accommodation; blindness and low vision
|
Sense Organs | 0.963 | 0.935 – 0.992 | 0.0121 | 6045 | 25457 | exclusion | phecode |
| 367.1 | Myopia | Sense Organs | 0.933 | 0.899 – 0.968 | 0.000237 | 3563 | 23321 | exclusion | phecode |
| 367.2 | Astigmatism | Sense Organs | 0.935 | 0.898 – 0.974 | 0.0012 | 2846 | 21384 | exclusion | phecode |
| 367.8 | Hypermetropia | Sense Organs | 0.97 | 0.914 – 1.03 | 0.326 | 1268 | 11720 | exclusion | phecode |
| 367.9 | Blindness and low vision | Sense Organs | 1.04 | 0.967 – 1.12 | 0.281 | 807 | 7734 | exclusion | phecode |
| 368 | Visual disturbances | Sense Organs | 1 | 0.968 – 1.04 | 0.895 | 3752 | 26567 | exclusion | phecode |
| 368.1 | Amblyopia | Sense Organs | 0.966 | 0.874 – 1.07 | 0.506 | 442 | 4230 | exclusion | phecode |
| 368.2 | Diplopia and disorders of binocular vision | Sense Organs | 0.98 | 0.905 – 1.06 | 0.631 | 693 | 6786 | exclusion | phecode |
| 368.3 | Anisometropia | Sense Organs | 0.924 | 0.783 – 1.09 | 0.348 | 158 | 1381 | exclusion | phecode |
| 368.4 | Visual field defects | Sense Organs | 1.01 | 0.933 – 1.1 | 0.755 | 667 | 6785 | exclusion | phecode |
| 368.9 | Subjective visual disturbances | Sense Organs | 0.95 | 0.876 – 1.03 | 0.214 | 684 | 6797 | exclusion | phecode |
| 368.91 | Psychophysical visual disturbances | Sense Organs | 0.785 | 0.611 – 1.01 | 0.0574 | 65 | 686 | exclusion | phecode |
| 369 | Infection of the eye | Sense Organs | 0.949 | 0.908 – 0.992 | 0.0218 | 2282 | 19442 | exclusion | phecode |
| 369.2 | Eye infection, viral | Sense Organs | 0.978 | 0.875 – 1.09 | 0.687 | 360 | 3328 | exclusion | phecode |
| 369.5 | Conjunctivitis, infectious | Sense Organs | 0.934 | 0.89 – 0.98 | 0.00562 | 1961 | 17264 | exclusion | phecode |
| 370 | Keratitis | Sense Organs | 0.946 | 0.882 – 1.01 | 0.122 | 902 | 8446 | exclusion | phecode |
| 370.1 | Corneal ulcer | Sense Organs | 1.03 | 0.877 – 1.21 | 0.706 | 167 | 1480 | exclusion | phecode |
| 370.2 | Superficial keratitis | Sense Organs | 0.901 | 0.808 – 1.01 | 0.0634 | 360 | 3424 | exclusion | phecode |
| 370.3 | Keratoconjunctivitis | Sense Organs | 0.854 | 0.768 – 0.95 | 0.00365 | 400 | 3929 | exclusion | phecode |
| 370.31 | Keratoconjunctivitis sicca | Sense Organs | 0.747 | 0.611 – 0.913 | 0.00444 | 104 | 1055 | exclusion | phecode |
| 371 | Inflammation of the eye | Sense Organs | 0.964 | 0.926 – 1 | 0.0771 | 2837 | 21039 | exclusion | phecode |
| 371.1 | Uveitis, noninfectious or NOS | Sense Organs | 0.976 | 0.869 – 1.1 | 0.684 | 328 | 3391 | exclusion | phecode |
| 371.2 | Conjunctivitis, noninfectious | Sense Organs | 0.968 | 0.89 – 1.05 | 0.455 | 616 | 5984 | exclusion | phecode |
| 371.21 | Allergic conjunctivitis | Sense Organs | 0.956 | 0.872 – 1.05 | 0.331 | 524 | 5072 | exclusion | phecode |
| 371.3 | Inflammation of eyelids | Sense Organs | 0.955 | 0.912 – 1 | 0.0534 | 2145 | 17095 | exclusion | phecode |
| 371.33 | Noninfectious dermatoses of eyelid | Sense Organs | 0.908 | 0.724 – 1.14 | 0.399 | 91 | 881 | exclusion | phecode |
| 372 | Disorders of conjunctiva | Sense Organs | 0.955 | 0.881 – 1.04 | 0.266 | 697 | 6568 | exclusion | phecode |
| 374 | Other disorders of eyelids | Sense Organs | 0.993 | 0.944 – 1.05 | 0.798 | 1795 | 14991 | exclusion | phecode |
| 374.1 | Ectropion or entropion | Sense Organs | 0.994 | 0.869 – 1.14 | 0.935 | 244 | 2310 | exclusion | phecode |
| 374.2 | Lagophthalmos | Sense Organs | 1.08 | 0.903 – 1.28 | 0.417 | 141 | 1474 | exclusion | phecode |
| 374.3 | Ptosis of eyelid | Sense Organs | 1.02 | 0.935 – 1.1 | 0.708 | 651 | 6343 | exclusion | phecode |
| 374.6 | Dermatochalasis | Sense Organs | 0.984 | 0.901 – 1.08 | 0.728 | 578 | 5533 | exclusion | phecode |
| 375 | Disorders of lacrimal system | Sense Organs | 0.94 | 0.899 – 0.984 | 0.00749 | 2317 | 16616 | exclusion | phecode |
| 375.1 | Dry eyes | Sense Organs | 0.929 | 0.889 – 0.97 | 0.000911 | 2538 | 17068 | exclusion | phecode |
| 375.2 | Epiphora | Sense Organs | 1.05 | 0.92 – 1.2 | 0.478 | 270 | 2640 | exclusion | phecode |
| 376 | Disorders of the orbit | Sense Organs | 1.02 | 0.889 – 1.16 | 0.802 | 249 | 2293 | exclusion | phecode |
| 377 | Disorders of optic nerve and visual pathways | Sense Organs | 1.01 | 0.924 – 1.09 | 0.893 | 616 | 5798 | exclusion | phecode |
| 377.1 | Optic atrophy | Sense Organs | 0.958 | 0.819 – 1.12 | 0.593 | 189 | 1722 | exclusion | phecode |
| 377.3 | Optic neuritis/neuropathy | Sense Organs | 1.03 | 0.926 – 1.14 | 0.603 | 393 | 3777 | exclusion | phecode |
| 378 |
Strabismus and other disorders of binocular eyeStrabismus and other disorders of binocular eye movements
|
Sense Organs | 0.989 | 0.921 – 1.06 | 0.763 | 850 | 8038 | exclusion | phecode |
| 378.1 | Strabismus (not specified as paralytic) | Sense Organs | 0.951 | 0.87 – 1.04 | 0.27 | 555 | 5247 | exclusion | phecode |
| 378.2 | Nystagmus and other irregular eye movements | Sense Organs | 1.02 | 0.836 – 1.25 | 0.842 | 112 | 1100 | exclusion | phecode |
| 378.5 | Paralytic strabismus | Sense Organs | 0.903 | 0.786 – 1.04 | 0.146 | 229 | 2213 | exclusion | phecode |
| 379 | Other disorders of eye | Sense Organs | 0.933 | 0.897 – 0.972 | 0.000742 | 3125 | 19299 | exclusion | phecode |
| 379.1 | Scleritis and episcleritis | Sense Organs | 0.933 | 0.774 – 1.12 | 0.465 | 118 | 1190 | exclusion | phecode |
| 379.2 | Disorders of vitreous body | Sense Organs | 0.901 | 0.859 – 0.945 | 1.91e-05 | 2156 | 14125 | exclusion | phecode |
| 379.3 | Aphakia and other disorders of lens | Sense Organs | 0.969 | 0.768 – 1.22 | 0.787 | 79 | 751 | exclusion | phecode |
| 379.4 | Anomalies of pupillary function | Sense Organs | 0.938 | 0.799 – 1.1 | 0.43 | 177 | 1792 | exclusion | phecode |
| 379.5 | Disorders of iris and ciliary body | Sense Organs | 1.07 | 0.921 – 1.24 | 0.372 | 196 | 1780 | exclusion | phecode |
| 379.51 | Pigmentary iris degeneration | Sense Organs | 0.823 | 0.615 – 1.1 | 0.189 | 52 | 432 | exclusion | phecode |
| 379.9 | Pain, swelling or discharge of eye | Sense Organs | 0.956 | 0.886 – 1.03 | 0.245 | 767 | 7476 | exclusion | phecode |
| 380 | Disorders of external ear | Sense Organs | 0.919 | 0.868 – 0.973 | 0.00392 | 1415 | 12607 | exclusion | phecode |
| 380.1 | Otitis externa | Sense Organs | 1.01 | 0.947 – 1.08 | 0.703 | 999 | 9732 | exclusion | phecode |
| 380.4 | Impacted cerumen | Sense Organs | 0.929 | 0.881 – 0.979 | 0.00557 | 1676 | 14744 | exclusion | phecode |
| 381 | Otitis media and Eustachian tube disorders | Sense Organs | 0.981 | 0.944 – 1.02 | 0.333 | 3059 | 25019 | exclusion | phecode |
| 381.1 | Otitis media | Sense Organs | 0.996 | 0.953 – 1.04 | 0.865 | 2256 | 20984 | exclusion | phecode |
| 381.11 | Suppurative and unspecified otitis media | Sense Organs | 1.01 | 0.959 – 1.06 | 0.809 | 1922 | 18147 | exclusion | phecode |
| 381.2 | Eustachian tube disorders | Sense Organs | 0.942 | 0.888 – 1 | 0.0498 | 1266 | 12222 | exclusion | phecode |
| 381.3 | Mastoiditis & related conditions | Sense Organs | 0.984 | 0.799 – 1.21 | 0.878 | 103 | 1078 | exclusion | phecode |
| 381.9 | Otorrhea | Sense Organs | 1.05 | 0.923 – 1.2 | 0.437 | 244 | 2496 | exclusion | phecode |
| 382 | Otalgia | Sense Organs | 1.03 | 0.974 – 1.09 | 0.278 | 1334 | 13127 | exclusion | phecode |
| 383 | Otosclerosis | Sense Organs | 1.06 | 0.848 – 1.34 | 0.594 | 82 | 846 | exclusion | phecode |
| 384 | Other disorders of tympanic membrane | Sense Organs | 1.07 | 0.955 – 1.19 | 0.254 | 369 | 3601 | exclusion | phecode |
| 384.1 | Myringitis | Sense Organs | 1.48 | 1.05 – 2.08 | 0.0253 | 39 | 364 | exclusion | phecode |
| 384.4 | Perforation of tympanic membrane | Sense Organs | 1.06 | 0.931 – 1.2 | 0.398 | 285 | 2801 | exclusion | phecode |
| 385 | Other disorders of middle ear and mastoid | Sense Organs | 0.942 | 0.833 – 1.06 | 0.337 | 297 | 3025 | exclusion | phecode |
| 385.3 | Cholesteatoma | Sense Organs | 0.95 | 0.817 – 1.1 | 0.503 | 199 | 1964 | exclusion | phecode |
| 385.5 |
Tympanosclerosis and middle ear disease relatedTympanosclerosis and middle ear disease related to otitis media
|
Sense Organs | 0.955 | 0.761 – 1.2 | 0.688 | 83 | 839 | exclusion | phecode |
| 386 |
Vertiginous syndromes and other disorders ofVertiginous syndromes and other disorders of vestibular system
|
Sense Organs | 0.976 | 0.918 – 1.04 | 0.422 | 1233 | 11752 | exclusion | phecode |
| 386.1 | Meniere's disease | Sense Organs | 0.938 | 0.813 – 1.08 | 0.378 | 220 | 2049 | exclusion | phecode |
| 386.2 | Peripheral or central vertigo | Sense Organs | 0.971 | 0.909 – 1.04 | 0.383 | 1032 | 9843 | exclusion | phecode |
| 386.21 | Central origin vertigo | Sense Organs | 0.975 | 0.905 – 1.05 | 0.505 | 795 | 7583 | exclusion | phecode |
| 386.3 | Labyrinthitis | Sense Organs | 0.978 | 0.914 – 1.05 | 0.515 | 987 | 9409 | exclusion | phecode |
| 386.9 |
Dizziness and giddiness (Light-headedness andDizziness and giddiness (Light-headedness and vertigo)
|
Sense Organs | 1.01 | 0.982 – 1.05 | 0.4 | 4537 | 25697 | exclusion | phecode |
| 388 | Other disorders of ear | Sense Organs | 0.958 | 0.882 – 1.04 | 0.301 | 652 | 6361 | exclusion | phecode |
| 389 | Hearing loss | Sense Organs | 0.97 | 0.94 – 1 | 0.0612 | 5035 | 26051 | exclusion | phecode |
| 389.1 | Sensorineural hearing loss | Sense Organs | 0.935 | 0.895 – 0.976 | 0.00207 | 2497 | 18861 | exclusion | phecode |
| 389.2 | Conductive hearing loss | Sense Organs | 0.98 | 0.901 – 1.07 | 0.63 | 641 | 6413 | exclusion | phecode |
| 389.3 | Degenerative and vascular disorders of ear | Sense Organs | 1.1 | 0.892 – 1.35 | 0.379 | 99 | 1037 | exclusion | phecode |
| 389.4 | Tinnitus | Sense Organs | 0.923 | 0.874 – 0.975 | 0.0042 | 1503 | 14289 | exclusion | phecode |
| 389.5 | Disorders of acoustic nerve | Sense Organs | 0.993 | 0.792 – 1.25 | 0.953 | 92 | 818 | exclusion | phecode |
| 394 | Rheumatic disease of the heart valves | Circulatory System | 0.966 | 0.897 – 1.04 | 0.357 | 803 | 8015 | exclusion | phecode |
| 394.1 | Mitral valve stenosis and aortic valve stenosis | Circulatory System | 0.916 | 0.784 – 1.07 | 0.267 | 181 | 1905 | exclusion | phecode |
| 394.2 | Mitral valve disease | Circulatory System | 0.972 | 0.852 – 1.11 | 0.675 | 258 | 2655 | exclusion | phecode |
| 394.3 | Aortic valve disease | Circulatory System | 0.896 | 0.694 – 1.16 | 0.403 | 69 | 949 | exclusion | phecode |
| 394.4 | Acute rheumatic heart disease | Circulatory System | 0.768 | 0.541 – 1.09 | 0.139 | 30 | 326 | exclusion | phecode |
| 394.7 | Disease of tricuspid valve | Circulatory System | 1.02 | 0.913 – 1.15 | 0.683 | 332 | 3384 | exclusion | phecode |
| 395 | Heart valve disorders | Circulatory System | 1.01 | 0.964 – 1.05 | 0.724 | 2253 | 18259 | exclusion | phecode |
| 395.1 | Nonrheumatic mitral valve disorders | Circulatory System | 1.02 | 0.962 – 1.08 | 0.518 | 1299 | 12570 | exclusion | phecode |
| 395.2 | Nonrheumatic aortic valve disorders | Circulatory System | 1.02 | 0.952 – 1.08 | 0.638 | 1064 | 10037 | exclusion | phecode |
| 395.3 | Nonrheumatic tricuspid valve disorders | Circulatory System | 0.968 | 0.855 – 1.1 | 0.614 | 273 | 2859 | exclusion | phecode |
| 395.4 | Nonrheumatic pulmonary valve disorders | Circulatory System | 0.874 | 0.692 – 1.11 | 0.262 | 75 | 754 | exclusion | phecode |
| 395.6 | Heart valve replaced | Circulatory System | 0.982 | 0.901 – 1.07 | 0.682 | 592 | 6093 | exclusion | phecode |
| 396 | Abnormal heart sounds | Circulatory System | 0.996 | 0.958 – 1.04 | 0.853 | 2979 | 22820 | exclusion | phecode |
| 401 | Hypertension | Circulatory System | 1.09 | 1.06 – 1.12 | 2.31e-11 | 13985 | 17456 | exclusion | phecode |
| 401.1 | Essential hypertension | Circulatory System | 1.09 | 1.06 – 1.12 | 3.57e-11 | 13879 | 17453 | exclusion | phecode |
| 401.2 | Hypertensive heart and/or renal disease | Circulatory System | 1.11 | 1.06 – 1.18 | 5.36e-05 | 1898 | 10221 | exclusion | phecode |
| 401.21 | Hypertensive heart disease | Circulatory System | 1.17 | 1.06 – 1.28 | 0.00187 | 490 | 4244 | exclusion | phecode |
| 401.22 | Hypertensive chronic kidney disease | Circulatory System | 1.1 | 1.04 – 1.17 | 0.00137 | 1414 | 9044 | exclusion | phecode |
| 401.3 | Other hypertensive complications | Circulatory System | 1.1 | 1.04 – 1.16 | 0.000886 | 1631 | 11219 | exclusion | phecode |
| 411 | Ischemic Heart Disease | Circulatory System | 1.07 | 1.04 – 1.11 | 5.42e-05 | 4659 | 20516 | exclusion | phecode |
| 411.1 | Unstable angina (intermediate coronary syndrome) | Circulatory System | 1.1 | 1 – 1.21 | 0.0414 | 502 | 5125 | exclusion | phecode |
| 411.2 | Myocardial infarction | Circulatory System | 1.09 | 1.04 – 1.15 | 0.000717 | 1840 | 14030 | exclusion | phecode |
| 411.3 | Angina pectoris | Circulatory System | 1.14 | 1.07 – 1.21 | 1.74e-05 | 1322 | 11548 | exclusion | phecode |
| 411.4 | Coronary atherosclerosis | Circulatory System | 1.07 | 1.03 – 1.11 | 0.000445 | 3894 | 18307 | exclusion | phecode |
| 411.41 | Aneurysm and dissection of heart | Circulatory System | 1.17 | 0.926 – 1.47 | 0.191 | 86 | 897 | exclusion | phecode |
| 411.8 |
Other chronic ischemic heart diseaseOther chronic ischemic heart disease, unspecified
|
Circulatory System | 1.07 | 1.03 – 1.12 | 0.000462 | 3184 | 16971 | exclusion | phecode |
| 411.9 |
Other acute and subacute forms of ischemicOther acute and subacute forms of ischemic heart disease
|
Circulatory System | 1.05 | 0.914 – 1.2 | 0.517 | 244 | 2456 | exclusion | phecode |
| 414 | Other forms of chronic heart disease | Circulatory System | 1.03 | 0.982 – 1.09 | 0.196 | 1683 | 14712 | exclusion | phecode |
| 414.2 | ASCVD | Circulatory System | 0.975 | 0.876 – 1.09 | 0.649 | 377 | 4093 | exclusion | phecode |
| 415 | Pulmonary heart disease | Circulatory System | 1.04 | 0.988 – 1.09 | 0.145 | 1917 | 19176 | exclusion | phecode |
| 415.1 | Acute pulmonary heart disease | Circulatory System | 1.02 | 0.958 – 1.09 | 0.544 | 1124 | 11974 | exclusion | phecode |
| 415.11 | Pulmonary embolism and infarction, acute | Circulatory System | 1.02 | 0.959 – 1.09 | 0.523 | 1119 | 11935 | exclusion | phecode |
| 415.2 | Chronic pulmonary heart disease | Circulatory System | 1.06 | 0.995 – 1.14 | 0.0703 | 963 | 10702 | exclusion | phecode |
| 415.21 | Primary pulmonary hypertension | Circulatory System | 1.13 | 1.01 – 1.26 | 0.0307 | 360 | 4244 | exclusion | phecode |
| 416 | Cardiomegaly | Circulatory System | 1.03 | 0.959 – 1.11 | 0.387 | 783 | 7607 | exclusion | phecode |
| 418 | Nonspecific chest pain | Circulatory System | 1.04 | 1.01 – 1.07 | 0.0027 | 8146 | 23263 | exclusion | phecode |
| 418.1 | Precordial pain | Circulatory System | 1.04 | 0.97 – 1.12 | 0.264 | 869 | 8585 | exclusion | phecode |
| 420 | Carditis | Circulatory System | 1.04 | 0.974 – 1.12 | 0.235 | 955 | 9596 | exclusion | phecode |
| 420.1 | Myocarditis | Circulatory System | 0.957 | 0.728 – 1.26 | 0.755 | 60 | 648 | exclusion | phecode |
| 420.2 | Pericarditis | Circulatory System | 1 | 0.914 – 1.1 | 0.949 | 507 | 5185 | exclusion | phecode |
| 420.21 | Acute pericarditis | Circulatory System | 1.11 | 0.909 – 1.35 | 0.31 | 102 | 1111 | exclusion | phecode |
| 420.22 | Chronic pericarditis | Circulatory System | 0.98 | 0.754 – 1.27 | 0.879 | 64 | 737 | exclusion | phecode |
| 420.3 | Endocarditis | Circulatory System | 1.07 | 0.965 – 1.18 | 0.21 | 454 | 4492 | exclusion | phecode |
| 425 | Cardiomyopathy | Circulatory System | 1.05 | 0.99 – 1.12 | 0.1 | 1142 | 12055 | exclusion | phecode |
| 425.1 | Primary/intrinsic cardiomyopathies | Circulatory System | 1.05 | 0.982 – 1.12 | 0.159 | 1084 | 11479 | exclusion | phecode |
| 425.11 | Hypertrophic obstructive cardiomyopathy | Circulatory System | 1.06 | 0.881 – 1.28 | 0.536 | 124 | 1291 | exclusion | phecode |
| 425.12 | Other hypertrophic cardiomyopathy | Circulatory System | 1.12 | 0.932 – 1.35 | 0.228 | 128 | 1244 | exclusion | phecode |
| 425.2 | Secondary/extrinsic cardiomyopathies | Circulatory System | 1.01 | 0.865 – 1.17 | 0.923 | 185 | 1997 | exclusion | phecode |
| 425.8 | Other cardiomyopathy | Circulatory System | 1.07 | 0.811 – 1.41 | 0.639 | 58 | 602 | exclusion | phecode |
| 426 | Cardiac conduction disorders | Circulatory System | 1.05 | 1.01 – 1.08 | 0.00324 | 7376 | 18086 | exclusion | phecode |
| 426.2 | Atrioventricular [AV] block | Circulatory System | 1.04 | 0.966 – 1.11 | 0.322 | 996 | 7170 | exclusion | phecode |
| 426.21 | First degree AV block | Circulatory System | 1.06 | 0.975 – 1.15 | 0.174 | 666 | 5316 | exclusion | phecode |
| 426.22 | Mobitz II AV block | Circulatory System | 0.876 | 0.606 – 1.27 | 0.482 | 36 | 311 | exclusion | phecode |
| 426.23 | Second degree AV block | Circulatory System | 0.876 | 0.726 – 1.06 | 0.17 | 118 | 1081 | exclusion | phecode |
| 426.24 | Atrioventricular block, complete | Circulatory System | 0.997 | 0.871 – 1.14 | 0.964 | 241 | 2259 | exclusion | phecode |
| 426.25 | Other heart block | Circulatory System | 1.03 | 0.855 – 1.24 | 0.754 | 114 | 1014 | exclusion | phecode |
| 426.3 | Bundle branch block | Circulatory System | 0.995 | 0.935 – 1.06 | 0.87 | 1230 | 8946 | exclusion | phecode |
| 426.31 | Right bundle branch block | Circulatory System | 0.974 | 0.902 – 1.05 | 0.511 | 745 | 6693 | exclusion | phecode |
| 426.32 | Left bundle branch block | Circulatory System | 1 | 0.914 – 1.1 | 0.967 | 528 | 4825 | exclusion | phecode |
| 426.4 | Anomalous atrioventricular excitation | Circulatory System | 0.87 | 0.661 – 1.14 | 0.319 | 62 | 581 | exclusion | phecode |
| 426.7 | Abnormal electrocardiogram [ECG] [EKG] | Circulatory System | 1.05 | 1.02 – 1.08 | 0.00228 | 6436 | 17847 | exclusion | phecode |
| 426.8 | Other cardiac conduction disorders | Circulatory System | 1.1 | 0.991 – 1.22 | 0.0736 | 412 | 4226 | exclusion | phecode |
| 426.9 | Cardiac pacemaker/device in situ | Circulatory System | 1.05 | 0.975 – 1.12 | 0.211 | 904 | 7213 | exclusion | phecode |
| 426.91 | Cardiac pacemaker in situ | Circulatory System | 1.03 | 0.948 – 1.13 | 0.449 | 586 | 4869 | exclusion | phecode |
| 426.92 | Cardiac defibrillator in situ | Circulatory System | 1.04 | 0.938 – 1.15 | 0.476 | 427 | 4366 | exclusion | phecode |
| 427 | Cardiac dysrhythmias | Circulatory System | 1.03 | 1 – 1.06 | 0.0204 | 10894 | 18361 | exclusion | phecode |
| 427.1 | Paroxysmal tachycardia, unspecified | Circulatory System | 0.998 | 0.944 – 1.06 | 0.954 | 1452 | 12203 | exclusion | phecode |
| 427.11 | Paroxysmal supraventricular tachycardia | Circulatory System | 0.989 | 0.925 – 1.06 | 0.754 | 982 | 9423 | exclusion | phecode |
| 427.12 | Paroxysmal ventricular tachycardia | Circulatory System | 1.03 | 0.944 – 1.12 | 0.546 | 634 | 6170 | exclusion | phecode |
| 427.2 | Atrial fibrillation and flutter | Circulatory System | 1.02 | 0.98 – 1.07 | 0.292 | 2820 | 12459 | exclusion | phecode |
| 427.21 | Atrial fibrillation | Circulatory System | 1.02 | 0.977 – 1.07 | 0.35 | 2744 | 12241 | exclusion | phecode |
| 427.22 | Atrial flutter | Circulatory System | 0.962 | 0.895 – 1.03 | 0.288 | 908 | 6846 | exclusion | phecode |
| 427.3 | Other specified cardiac dysrhythmias | Circulatory System | 1.04 | 1 – 1.07 | 0.0248 | 5338 | 18205 | exclusion | phecode |
| 427.4 | Cardiac arrest and ventricular fibrillation | Circulatory System | 1.11 | 0.979 – 1.25 | 0.104 | 296 | 3251 | exclusion | phecode |
| 427.41 | Ventricular fibrillation and flutter | Circulatory System | 0.95 | 0.788 – 1.14 | 0.585 | 120 | 1286 | exclusion | phecode |
| 427.42 | Cardiac arrest | Circulatory System | 1.21 | 1.05 – 1.39 | 0.00826 | 225 | 2495 | exclusion | phecode |
| 427.5 | Arrhythmia (cardiac) NOS | Circulatory System | 1.02 | 0.982 – 1.05 | 0.33 | 4215 | 18118 | exclusion | phecode |
| 427.6 | Premature beats | Circulatory System | 0.987 | 0.931 – 1.05 | 0.656 | 1373 | 10630 | exclusion | phecode |
| 427.61 | Supraventricular premature beats | Circulatory System | 0.969 | 0.87 – 1.08 | 0.56 | 386 | 3832 | exclusion | phecode |
| 427.7 | Tachycardia NOS | Circulatory System | 1.07 | 1.03 – 1.11 | 0.000859 | 3351 | 18172 | exclusion | phecode |
| 427.8 | Sinoatrial node dysfunction (Bradycardia) | Circulatory System | 0.992 | 0.903 – 1.09 | 0.861 | 519 | 4437 | exclusion | phecode |
| 427.9 | Palpitations | Circulatory System | 0.982 | 0.943 – 1.02 | 0.376 | 2982 | 17272 | exclusion | phecode |
| 428 | Congestive heart failure; nonhypertensive | Circulatory System | 1.08 | 1.03 – 1.13 | 0.000736 | 2272 | 15464 | exclusion | phecode |
| 428.1 | Congestive heart failure (CHF) NOS | Circulatory System | 1.08 | 1.03 – 1.13 | 0.00223 | 1972 | 14543 | exclusion | phecode |
| 428.2 | Heart failure NOS | Circulatory System | 1.07 | 1.02 – 1.13 | 0.00445 | 1936 | 14001 | exclusion | phecode |
| 428.3 |
Heart failure with reduced EF [Systolic orHeart failure with reduced EF [Systolic or combined heart failure]
|
Circulatory System | 1.1 | 1.03 – 1.18 | 0.00651 | 924 | 8905 | exclusion | phecode |
| 428.4 |
Heart failure with preserved EF [DiastolicHeart failure with preserved EF [Diastolic heart failure]
|
Circulatory System | 1.07 | 0.998 – 1.15 | 0.0555 | 842 | 8095 | exclusion | phecode |
| 429 |
Ill-defined descriptions and complications ofIll-defined descriptions and complications of heart disease
|
Circulatory System | 1.04 | 1.01 – 1.06 | 0.0102 | 7888 | 22704 | exclusion | phecode |
| 429.1 | Heart transplant/surgery | Circulatory System | 1.07 | 0.986 – 1.16 | 0.106 | 680 | 7193 | exclusion | phecode |
| 429.2 | Abnormal function study of cardiovascular system | Circulatory System | 1.06 | 1.02 – 1.1 | 0.0023 | 3775 | 19850 | exclusion | phecode |
| 429.3 | Symptoms involving cardiovascular system | Circulatory System | 1.03 | 0.999 – 1.06 | 0.0617 | 6093 | 22629 | exclusion | phecode |
| 429.9 | Cardiac complications, not elsewhere classified | Circulatory System | 1 | 0.899 – 1.11 | 0.998 | 390 | 4183 | exclusion | phecode |
| 430 | Intracranial hemorrhage | Circulatory System | 1.11 | 1.01 – 1.22 | 0.0318 | 501 | 4820 | exclusion | phecode |
| 430.1 | Subarachnoid hemorrhage | Circulatory System | 1.34 | 1.12 – 1.59 | 0.00108 | 161 | 1579 | exclusion | phecode |
| 430.2 | Intracerebral hemorrhage | Circulatory System | 1.17 | 1.02 – 1.34 | 0.0251 | 249 | 2266 | exclusion | phecode |
| 430.3 | Subdural hemorrhage | Circulatory System | 1 | 0.851 – 1.19 | 0.956 | 172 | 1658 | exclusion | phecode |
| 433 | Cerebrovascular disease | Circulatory System | 1.07 | 1.03 – 1.11 | 0.000601 | 3047 | 20970 | exclusion | phecode |
| 433.1 | Occlusion and stenosis of precerebral arteries | Circulatory System | 1.12 | 1.04 – 1.19 | 0.0015 | 976 | 9428 | exclusion | phecode |
| 433.11 |
Occlusion of cerebral arteries, with cerebralOcclusion of cerebral arteries, with cerebral infarction
|
Circulatory System | 1.2 | 1.02 – 1.42 | 0.0305 | 160 | 1482 | exclusion | phecode |
| 433.12 | Cerebral atherosclerosis | Circulatory System | 1.45 | 1.03 – 2.05 | 0.0319 | 37 | 444 | exclusion | phecode |
| 433.2 | Occlusion of cerebral arteries | Circulatory System | 1.06 | 1 – 1.12 | 0.0346 | 1417 | 13368 | exclusion | phecode |
| 433.21 |
Cerebral artery occlusion, with cerebralCerebral artery occlusion, with cerebral infarction
|
Circulatory System | 1.07 | 1.01 – 1.13 | 0.0241 | 1367 | 12946 | exclusion | phecode |
| 433.3 | Cerebral ischemia | Circulatory System | 1.04 | 0.99 – 1.1 | 0.114 | 1557 | 14065 | exclusion | phecode |
| 433.31 | Transient cerebral ischemia | Circulatory System | 1.04 | 0.986 – 1.11 | 0.141 | 1368 | 12674 | exclusion | phecode |
| 433.5 | Cerebral aneurysm | Circulatory System | 1.23 | 1.08 – 1.4 | 0.00183 | 286 | 3092 | exclusion | phecode |
| 433.6 | Acute, but ill-defined cerebrovascular disease | Circulatory System | 1.05 | 0.926 – 1.2 | 0.428 | 267 | 2737 | exclusion | phecode |
| 433.8 | Late effects of cerebrovascular disease | Circulatory System | 1.13 | 1.02 – 1.25 | 0.0196 | 420 | 4216 | exclusion | phecode |
| 440 | Atherosclerosis | Circulatory System | 1.18 | 1.12 – 1.26 | 1.57e-08 | 1335 | 12047 | exclusion | phecode |
| 440.1 | Atherosclerosis of renal artery | Circulatory System | 1.17 | 0.961 – 1.42 | 0.118 | 122 | 1342 | exclusion | phecode |
| 440.2 | Atherosclerosis of the extremities | Circulatory System | 1.2 | 1.11 – 1.29 | 2.06e-06 | 813 | 8023 | exclusion | phecode |
| 440.21 |
Atherosclerosis of native arteries of theAtherosclerosis of native arteries of the extremities with ulceration or gangrene
|
Circulatory System | 1.36 | 1.14 – 1.63 | 0.000781 | 148 | 1572 | exclusion | phecode |
| 440.22 |
Atherosclerosis of native arteries of theAtherosclerosis of native arteries of the extremities with intermittent claudication
|
Circulatory System | 1.22 | 1.11 – 1.33 | 2.25e-05 | 552 | 5599 | exclusion | phecode |
| 440.9 | Atherosclerosis of aorta | Circulatory System | 1.23 | 1.11 – 1.36 | 6.12e-05 | 436 | 4546 | exclusion | phecode |
| 441 | Vascular insufficiency of intestine | Circulatory System | 1.2 | 1.06 – 1.36 | 0.00325 | 304 | 3218 | exclusion | phecode |
| 441.1 | Acute vascular insufficiency of intestine | Circulatory System | 1.14 | 0.955 – 1.36 | 0.146 | 141 | 1498 | exclusion | phecode |
| 441.2 | Chronic vascular insufficiency of intestine | Circulatory System | 1.49 | 1.18 – 1.88 | 0.000782 | 82 | 937 | exclusion | phecode |
| 442 | Other aneurysm | Circulatory System | 1.1 | 1.04 – 1.16 | 0.000862 | 1483 | 13347 | exclusion | phecode |
| 442.1 | Aortic aneurysm | Circulatory System | 1.12 | 1.05 – 1.2 | 0.000467 | 1043 | 9798 | exclusion | phecode |
| 442.11 | Abdominal aortic aneurysm | Circulatory System | 1.22 | 1.12 – 1.33 | 1.06e-05 | 565 | 5835 | exclusion | phecode |
| 442.2 | Aneurysm of iliac artery | Circulatory System | 1.04 | 0.841 – 1.29 | 0.708 | 97 | 1049 | exclusion | phecode |
| 442.3 | Aneurysm of artery of lower extremity | Circulatory System | 1.08 | 0.866 – 1.34 | 0.502 | 92 | 1004 | exclusion | phecode |
| 442.4 | Arterial dissection | Circulatory System | 0.927 | 0.751 – 1.15 | 0.484 | 99 | 1166 | exclusion | phecode |
| 442.8 | Aneurysm of other specified artery | Circulatory System | 1.03 | 0.897 – 1.18 | 0.686 | 233 | 2463 | exclusion | phecode |
| 443 | Peripheral vascular disease | Circulatory System | 1.07 | 1.01 – 1.12 | 0.0139 | 1751 | 15770 | exclusion | phecode |
| 443.1 | Raynaud's syndrome | Circulatory System | 0.953 | 0.868 – 1.05 | 0.311 | 515 | 5014 | exclusion | phecode |
| 443.7 |
Peripheral angiopathy in diseases classifiedPeripheral angiopathy in diseases classified elsewhere
|
Circulatory System | 1.03 | 0.843 – 1.25 | 0.78 | 116 | 1263 | exclusion | phecode |
| 443.8 | Other specified peripheral vascular diseases | Circulatory System | 1.08 | 1.02 – 1.14 | 0.00545 | 1438 | 13772 | exclusion | phecode |
| 443.9 | Peripheral vascular disease, unspecified | Circulatory System | 1.14 | 1.07 – 1.21 | 1.7e-05 | 1227 | 11443 | exclusion | phecode |
| 444 | Arterial embolism and thrombosis | Circulatory System | 1.19 | 1.08 – 1.31 | 0.000356 | 494 | 5257 | exclusion | phecode |
| 444.1 |
Arterial embolism and thrombosis of lowerArterial embolism and thrombosis of lower extremity artery
|
Circulatory System | 1.31 | 1.11 – 1.54 | 0.0011 | 168 | 1872 | exclusion | phecode |
| 444.2 | Embolism and thrombosis of abdominal aorta | Circulatory System | 1.43 | 1.12 – 1.81 | 0.004 | 74 | 888 | exclusion | phecode |
| 446 | Polyarteritis nodosa and allied conditions | Circulatory System | 1.08 | 0.954 – 1.23 | 0.215 | 266 | 2912 | exclusion | phecode |
| 446.4 | Wegener's granulomatosis | Circulatory System | 0.962 | 0.755 – 1.23 | 0.755 | 66 | 737 | exclusion | phecode |
| 446.5 | Giant cell arteritis | Circulatory System | 1.18 | 0.838 – 1.68 | 0.338 | 39 | 409 | exclusion | phecode |
| 446.9 | Arteritis NOS | Circulatory System | 1.05 | 0.887 – 1.23 | 0.598 | 164 | 1904 | exclusion | phecode |
| 447 | Other disorders of arteries and arterioles | Circulatory System | 1.03 | 0.978 – 1.09 | 0.239 | 1496 | 14364 | exclusion | phecode |
| 447.1 | Stricture of artery | Circulatory System | 1.32 | 1.16 – 1.49 | 2.23e-05 | 278 | 3167 | exclusion | phecode |
| 447.7 | Aortic ectasia | Circulatory System | 0.963 | 0.874 – 1.06 | 0.445 | 467 | 4646 | exclusion | phecode |
| 448 | Disease of capillaries | Circulatory System | 0.918 | 0.853 – 0.988 | 0.0233 | 827 | 7718 | exclusion | phecode |
| 450 | Noninfectious disorders of lymphatic channels | Circulatory System | 0.996 | 0.94 – 1.05 | 0.878 | 1391 | 13518 | exclusion | phecode |
| 451 | Phlebitis and thrombophlebitis | Circulatory System | 0.995 | 0.903 – 1.1 | 0.925 | 460 | 4705 | exclusion | phecode |
| 451.2 |
Phlebitis and thrombophlebitis of lowerPhlebitis and thrombophlebitis of lower extremities
|
Circulatory System | 0.863 | 0.726 – 1.03 | 0.0959 | 158 | 1576 | exclusion | phecode |
| 452 | Other venous embolism and thrombosis | Circulatory System | 1.04 | 0.997 – 1.08 | 0.0737 | 3079 | 20134 | exclusion | phecode |
| 452.1 | Iatrogenic pulmonary embolism and infarction | Circulatory System | 0.897 | 0.767 – 1.05 | 0.178 | 184 | 1779 | exclusion | phecode |
| 452.2 | Deep vein thrombosis [DVT] | Circulatory System | 1.02 | 0.971 – 1.07 | 0.463 | 2053 | 17772 | exclusion | phecode |
| 452.8 | Postphlebitic syndrome | Circulatory System | 0.875 | 0.719 – 1.07 | 0.183 | 111 | 1099 | exclusion | phecode |
| 453 | Chronic venous hypertension | Circulatory System | 1.02 | 0.855 – 1.22 | 0.805 | 135 | 1417 | exclusion | phecode |
| 454 | Varicose veins | Circulatory System | 0.966 | 0.92 – 1.01 | 0.168 | 1858 | 16150 | exclusion | phecode |
| 454.1 | Varicose veins of lower extremity | Circulatory System | 0.97 | 0.92 – 1.02 | 0.269 | 1581 | 13809 | exclusion | phecode |
| 454.11 | Varicose veins of lower extremity, symptomtic | Circulatory System | 0.979 | 0.916 – 1.05 | 0.532 | 1010 | 9637 | exclusion | phecode |
| 455 | Hemorrhoids | Circulatory System | 0.968 | 0.934 – 1 | 0.078 | 3811 | 20036 | exclusion | phecode |
| 456 | Chronic venous insufficiency [CVI] | Circulatory System | 1 | 0.954 – 1.05 | 0.954 | 1984 | 16233 | exclusion | phecode |
| 457 |
Encounter for long-term (current) use ofEncounter for long-term (current) use of anticoagulants, antithrombotics, aspirin
|
Circulatory System | 1.03 | 0.968 – 1.1 | 0.339 | 1104 | 9261 | exclusion | phecode |
| 457.2 |
Encounter for long-term (current) use ofEncounter for long-term (current) use of antiplatelets/antithrombotics
|
Circulatory System | 1.11 | 0.951 – 1.3 | 0.183 | 168 | 1772 | exclusion | phecode |
| 457.3 | Encounter for long-term (current) use of aspirin | Circulatory System | 1.04 | 0.972 – 1.11 | 0.256 | 1036 | 8868 | exclusion | phecode |
| 458 | Hypotension | Circulatory System | 1.05 | 1.01 – 1.09 | 0.0145 | 3034 | 21677 | exclusion | phecode |
| 458.1 | Orthostatic hypotension | Circulatory System | 1.07 | 0.996 – 1.15 | 0.0646 | 820 | 8065 | exclusion | phecode |
| 458.2 | Iatrogenic hypotension | Circulatory System | 1.11 | 1.02 – 1.21 | 0.0119 | 615 | 6629 | exclusion | phecode |
| 458.9 | Hypotension NOS | Circulatory System | 1.06 | 1.01 – 1.1 | 0.0101 | 2738 | 20883 | exclusion | phecode |
| 459 | Other disorders of circulatory system | Circulatory System | 1.04 | 1 – 1.07 | 0.0369 | 4709 | 23874 | exclusion | phecode |
| 459.1 | Hemorrhage NOS | Circulatory System | 1.02 | 0.929 – 1.11 | 0.728 | 543 | 5265 | exclusion | phecode |
| 459.7 | Blood vessel replaced | Circulatory System | 1.1 | 1.02 – 1.19 | 0.0131 | 761 | 8223 | exclusion | phecode |
| 459.9 | Circulatory disease NEC | Circulatory System | 1.04 | 1 – 1.08 | 0.0315 | 3991 | 22808 | exclusion | phecode |
| 464 | Acute sinusitis | Respiratory | 0.983 | 0.947 – 1.02 | 0.368 | 3380 | 21626 | exclusion | phecode |
| 465 |
Acute upper respiratory infections of multipleAcute upper respiratory infections of multiple or unspecified sites
|
Respiratory | 0.983 | 0.956 – 1.01 | 0.241 | 6775 | 23866 | exclusion | phecode |
| 465.2 | Acute pharyngitis | Respiratory | 0.961 | 0.928 – 0.996 | 0.029 | 3890 | 22126 | exclusion | phecode |
| 465.4 | Acute laryngitis and tracheitis | Respiratory | 0.977 | 0.862 – 1.11 | 0.716 | 295 | 2996 | exclusion | phecode |
| 470 | Septal Deviations/Turbinate Hypertrophy | Respiratory | 0.989 | 0.932 – 1.05 | 0.722 | 1286 | 12236 | exclusion | phecode |
| 471 | Nasal polyps | Respiratory | 1.01 | 0.91 – 1.12 | 0.838 | 412 | 3925 | exclusion | phecode |
| 472 | Chronic pharyngitis and nasopharyngitis | Respiratory | 0.988 | 0.928 – 1.05 | 0.693 | 1185 | 11357 | exclusion | phecode |
| 473 | Diseases of the larynx and vocal cords | Respiratory | 1.01 | 0.965 – 1.06 | 0.582 | 1887 | 16409 | exclusion | phecode |
| 473.1 | Chronic laryngitis | Respiratory | 1.14 | 0.806 – 1.6 | 0.464 | 38 | 434 | exclusion | phecode |
| 473.3 | Paralysis/spasm of vocal cords or larynx | Respiratory | 0.988 | 0.886 – 1.1 | 0.834 | 383 | 4009 | exclusion | phecode |
| 473.4 | Voice disturbance | Respiratory | 1.02 | 0.966 – 1.08 | 0.466 | 1447 | 14035 | exclusion | phecode |
| 474 | Acute and chronic tonsillitis | Respiratory | 1 | 0.925 – 1.08 | 0.986 | 723 | 6138 | exclusion | phecode |
| 474.1 | Acute tonsillitis | Respiratory | 0.994 | 0.879 – 1.12 | 0.928 | 298 | 2607 | exclusion | phecode |
| 474.2 | Chronic tonsillitis and adenoiditis | Respiratory | 1.02 | 0.935 – 1.12 | 0.641 | 572 | 5048 | exclusion | phecode |
| 475 | Chronic sinusitis | Respiratory | 0.998 | 0.959 – 1.04 | 0.903 | 3024 | 18669 | exclusion | phecode |
| 475.9 | Postnasal drip | Respiratory | 0.932 | 0.855 – 1.02 | 0.106 | 617 | 5766 | exclusion | phecode |
| 476 | Allergic rhinitis | Respiratory | 0.984 | 0.959 – 1.01 | 0.233 | 8812 | 18809 | exclusion | phecode |
| 477 | Epistaxis or throat hemorrhage | Respiratory | 1.04 | 0.961 – 1.12 | 0.343 | 743 | 7335 | exclusion | phecode |
| 478 | Throat pain | Respiratory | 1.08 | 0.953 – 1.22 | 0.237 | 296 | 2847 | exclusion | phecode |
| 479 | Other upper respiratory disease | Respiratory | 1.01 | 0.976 – 1.05 | 0.512 | 3733 | 18758 | exclusion | phecode |
| 480 | Pneumonia | Respiratory | 1.06 | 1.02 – 1.1 | 0.00232 | 3645 | 25024 | exclusion | phecode |
| 480.1 | Bacterial pneumonia | Respiratory | 1.06 | 0.976 – 1.15 | 0.171 | 678 | 7167 | exclusion | phecode |
| 480.11 | Pneumococcal pneumonia | Respiratory | 1.04 | 0.93 – 1.16 | 0.487 | 344 | 3539 | exclusion | phecode |
| 480.12 | Pseudomonal pneumonia | Respiratory | 0.974 | 0.771 – 1.23 | 0.828 | 79 | 951 | exclusion | phecode |
| 480.13 | MRSA pneumonia | Respiratory | 1.26 | 0.976 – 1.62 | 0.0757 | 68 | 773 | exclusion | phecode |
| 480.2 | Viral pneumonia | Respiratory | 1.15 | 0.956 – 1.39 | 0.136 | 119 | 1237 | exclusion | phecode |
| 480.3 | Pneumonia due to fungus (mycoses) | Respiratory | 1.07 | 0.837 – 1.35 | 0.607 | 72 | 1006 | exclusion | phecode |
| 480.5 | Bronchopneumonia and lung abscess | Respiratory | 0.902 | 0.719 – 1.13 | 0.375 | 80 | 823 | exclusion | phecode |
| 481 | Influenza | Respiratory | 1.03 | 0.963 – 1.11 | 0.369 | 944 | 9066 | exclusion | phecode |
| 483 | Acute bronchitis and bronchiolitis | Respiratory | 0.974 | 0.932 – 1.02 | 0.251 | 2281 | 20056 | exclusion | phecode |
| 495 | Asthma | Respiratory | 1.05 | 1.02 – 1.08 | 0.00191 | 6048 | 23040 | exclusion | phecode |
| 495.1 | Chronic obstructive asthma | Respiratory | 1.17 | 1.02 – 1.36 | 0.0281 | 219 | 2563 | exclusion | phecode |
| 495.11 | Chronic obstructive asthma with exacerbation | Respiratory | 0.863 | 0.622 – 1.2 | 0.38 | 42 | 501 | exclusion | phecode |
| 495.2 | Asthma with exacerbation | Respiratory | 0.964 | 0.907 – 1.02 | 0.242 | 1204 | 11589 | exclusion | phecode |
| 496 | Chronic airway obstruction | Respiratory | 1.3 | 1.25 – 1.35 | 2.39e-35 | 2792 | 18591 | exclusion | phecode |
| 496.1 | Emphysema | Respiratory | 1.44 | 1.34 – 1.54 | 2.98e-24 | 935 | 11941 | exclusion | phecode |
| 496.2 | Chronic bronchitis | Respiratory | 1.34 | 1.28 – 1.4 | 1.92e-34 | 2169 | 17230 | exclusion | phecode |
| 496.21 | Obstructive chronic bronchitis | Respiratory | 1.35 | 1.28 – 1.42 | 6.49e-33 | 1922 | 16325 | exclusion | phecode |
| 496.3 | Bronchiectasis | Respiratory | 1.03 | 0.911 – 1.16 | 0.659 | 297 | 3393 | exclusion | phecode |
| 497 | Bronchitis | Respiratory | 1.02 | 0.96 – 1.08 | 0.542 | 1291 | 12708 | exclusion | phecode |
| 498 | Acute bronchospasm | Respiratory | 0.967 | 0.861 – 1.09 | 0.575 | 332 | 3429 | exclusion | phecode |
| 499 | Cystic fibrosis | Respiratory | 1.07 | 0.876 – 1.3 | 0.518 | 112 | 1071 | exclusion | phecode |
| 500 | Lung disease due to external agents | Respiratory | 1.11 | 0.989 – 1.25 | 0.075 | 314 | 3348 | exclusion | phecode |
| 500.1 | Extrinsic allergic alveolitis | Respiratory | 1.08 | 0.825 – 1.42 | 0.569 | 58 | 596 | exclusion | phecode |
| 500.2 | Pneumoconiosis | Respiratory | 1.43 | 1.02 – 2.01 | 0.0394 | 34 | 381 | exclusion | phecode |
| 501 | Pneumonitis due to inhalation of food or vomitus | Respiratory | 1.22 | 1.09 – 1.36 | 0.00053 | 352 | 3839 | exclusion | phecode |
| 502 | Postinflammatory pulmonary fibrosis | Respiratory | 1.11 | 0.999 – 1.22 | 0.0517 | 426 | 4930 | exclusion | phecode |
| 503 | Pulmonary congestion and hypostasis | Respiratory | 1.15 | 1.05 – 1.27 | 0.00408 | 460 | 5115 | exclusion | phecode |
| 504 | Other alveolar and parietoalveolar pneumonopathy | Respiratory | 1.07 | 0.95 – 1.21 | 0.256 | 301 | 3575 | exclusion | phecode |
| 504.1 | Idiopathic fibrosing alveolitis | Respiratory | 1.01 | 0.857 – 1.2 | 0.878 | 148 | 1810 | exclusion | phecode |
| 505 | Other pulmonary inflamation or edema | Respiratory | 1.07 | 0.995 – 1.14 | 0.0675 | 894 | 9723 | exclusion | phecode |
| 506 | Empyema and pneumothorax | Respiratory | 1.07 | 1.02 – 1.13 | 0.00907 | 1601 | 16407 | exclusion | phecode |
| 507 | Pleurisy; pleural effusion | Respiratory | 1.04 | 0.992 – 1.1 | 0.095 | 1679 | 17047 | exclusion | phecode |
| 508 |
Pulmonary collapse; interstitial andPulmonary collapse; interstitial and compensatory emphysema
|
Respiratory | 1.06 | 0.999 – 1.12 | 0.0532 | 1385 | 14488 | exclusion | phecode |
| 509 | Respiratory failure, insufficiency, arrest | Respiratory | 1.11 | 1.06 – 1.16 | 5.72e-06 | 2254 | 19428 | exclusion | phecode |
| 509.1 | Respiratory failure | Respiratory | 1.15 | 1.08 – 1.23 | 8.21e-06 | 1108 | 11988 | exclusion | phecode |
| 509.2 | Respiratory insufficiency | Respiratory | 1.16 | 1.07 – 1.26 | 0.000436 | 640 | 7323 | exclusion | phecode |
| 509.3 |
Pulmonary insufficiency or respiratory failurePulmonary insufficiency or respiratory failure following trauma and surgery
|
Respiratory | 1.14 | 1.06 – 1.22 | 0.000252 | 936 | 10295 | exclusion | phecode |
| 509.8 |
Dependence on respirator [Ventilator] orDependence on respirator [Ventilator] or supplemental oxygen
|
Respiratory | 1.12 | 1.05 – 1.2 | 0.00114 | 929 | 10706 | exclusion | phecode |
| 510 | Other diseases of lung | Respiratory | 1.03 | 0.988 – 1.07 | 0.176 | 3158 | 23815 | exclusion | phecode |
| 510.2 | Lung transplant | Respiratory | 1.01 | 0.807 – 1.25 | 0.958 | 88 | 1172 | exclusion | phecode |
| 512 | Other symptoms of respiratory system | Respiratory | 1.04 | 1.02 – 1.07 | 0.000467 | 11987 | 19542 | exclusion | phecode |
| 512.1 | Wheezing | Respiratory | 1.12 | 1.05 – 1.21 | 0.00121 | 899 | 9011 | exclusion | phecode |
| 512.2 | Painful respiration | Respiratory | 1.05 | 0.993 – 1.11 | 0.091 | 1555 | 14392 | exclusion | phecode |
| 512.3 | Abnormal chest sounds | Respiratory | 1.07 | 0.914 – 1.26 | 0.39 | 170 | 1697 | exclusion | phecode |
| 512.7 | Shortness of breath | Respiratory | 1.07 | 1.04 – 1.11 | 5.45e-06 | 6081 | 19474 | exclusion | phecode |
| 512.8 | Cough | Respiratory | 1.04 | 1.01 – 1.07 | 0.0165 | 6300 | 19538 | exclusion | phecode |
| 512.9 | Other dyspnea | Respiratory | 1.05 | 1.02 – 1.08 | 0.0011 | 6706 | 19497 | exclusion | phecode |
| 513 | Respiratory abnormalities | Respiratory | 1.05 | 1.02 – 1.08 | 0.000567 | 8021 | 23487 | exclusion | phecode |
| 513.3 | Hypoventilation | Respiratory | 1.11 | 1.02 – 1.22 | 0.022 | 541 | 5617 | exclusion | phecode |
| 513.31 | Apnea | Respiratory | 1.1 | 0.969 – 1.24 | 0.143 | 290 | 3048 | exclusion | phecode |
| 513.32 | Orthopnea | Respiratory | 1.07 | 0.887 – 1.3 | 0.46 | 122 | 1293 | exclusion | phecode |
| 513.4 | Hyperventilation | Respiratory | 1.07 | 0.949 – 1.21 | 0.264 | 288 | 3217 | exclusion | phecode |
| 513.8 | Disorders of diaphragm | Respiratory | 0.988 | 0.835 – 1.17 | 0.891 | 151 | 1545 | exclusion | phecode |
| 514 | Abnormal findings examination of lungs | Respiratory | 1.09 | 1.05 – 1.13 | 1.89e-05 | 3103 | 22871 | exclusion | phecode |
| 514.1 |
Abnormal results of function study of pulmonaryAbnormal results of function study of pulmonary system
|
Respiratory | 1.13 | 0.95 – 1.33 | 0.17 | 149 | 1603 | exclusion | phecode |
| 514.2 | Solitary pulmonary nodule | Respiratory | 1.11 | 1.05 – 1.17 | 6.06e-05 | 1739 | 17198 | exclusion | phecode |
| 516 | Abnormal sputum | Respiratory | 1.2 | 1.08 – 1.33 | 0.000461 | 417 | 4668 | exclusion | phecode |
| 516.1 | Hemoptysis | Respiratory | 1.22 | 1.09 – 1.36 | 0.000622 | 346 | 3918 | exclusion | phecode |
| 519 |
Other diseases of respiratory system, notOther diseases of respiratory system, not elsewhere classified
|
Respiratory | 1.04 | 1 – 1.07 | 0.0439 | 3876 | 26581 | exclusion | phecode |
| 519.1 | Tracheostomy complications | Respiratory | 1.13 | 0.925 – 1.39 | 0.229 | 113 | 1398 | exclusion | phecode |
| 519.2 | Respiratory complications | Respiratory | 1.08 | 0.95 – 1.23 | 0.235 | 255 | 2807 | exclusion | phecode |
| 519.8 | Other diseases of respiratory system, NEC | Respiratory | 0.977 | 0.913 – 1.04 | 0.495 | 981 | 10376 | exclusion | phecode |
| 519.9 |
Symptoms involving respiratory system and otherSymptoms involving respiratory system and other chest symptoms
|
Respiratory | 1.05 | 1.01 – 1.1 | 0.0146 | 2761 | 22817 | exclusion | phecode |
| 520 | Disorders of tooth development | Digestive | 1.15 | 1.01 – 1.31 | 0.0354 | 259 | 2685 | exclusion | phecode |
| 520.1 | Hereditary disturbances in tooth structure | Digestive | 1.35 | 1.1 – 1.65 | 0.00393 | 106 | 1071 | exclusion | phecode |
| 520.2 | Disturbances in tooth eruption | Digestive | 1.03 | 0.874 – 1.21 | 0.732 | 166 | 1687 | exclusion | phecode |
| 521 | Diseases of hard tissues of teeth | Digestive | 1.18 | 1.09 – 1.29 | 0.000103 | 611 | 6061 | exclusion | phecode |
| 521.1 | Dental caries | Digestive | 1.2 | 1.1 – 1.31 | 6.37e-05 | 572 | 5643 | exclusion | phecode |
| 521.2 | Dental abrasion, erosion and attrition | Digestive | 1 | 0.699 – 1.44 | 0.981 | 30 | 372 | exclusion | phecode |
| 522 | Diseases of pulp and periapical tissues | Digestive | 1.19 | 1.07 – 1.33 | 0.00152 | 380 | 3702 | exclusion | phecode |
| 522.5 | Periapical abscess | Digestive | 1.18 | 1.05 – 1.33 | 0.00542 | 328 | 3185 | exclusion | phecode |
| 523 | Gingival and periodontal diseases | Digestive | 1.17 | 1.07 – 1.29 | 0.00116 | 489 | 4731 | exclusion | phecode |
| 523.1 | Gingivitis | Digestive | 1.1 | 0.889 – 1.36 | 0.388 | 97 | 952 | exclusion | phecode |
| 523.3 | Periodontitis (acute or chronic) | Digestive | 1.24 | 1.09 – 1.42 | 0.00133 | 256 | 2448 | exclusion | phecode |
| 523.31 | Acute periodontitis | Digestive | 1.29 | 1.11 – 1.49 | 0.000591 | 219 | 2079 | exclusion | phecode |
| 523.32 | Chronic periodontitis | Digestive | 1.11 | 0.881 – 1.41 | 0.367 | 80 | 805 | exclusion | phecode |
| 524 | Dentofacial anomalies, including malocclusion | Digestive | 0.967 | 0.855 – 1.09 | 0.6 | 281 | 2793 | exclusion | phecode |
| 524.3 | Anomalies of tooth position/malocclusion | Digestive | 0.916 | 0.788 – 1.06 | 0.253 | 186 | 1774 | exclusion | phecode |
| 525 |
Other diseases of the teeth and supportingOther diseases of the teeth and supporting structures
|
Digestive | 1.23 | 1.14 – 1.33 | 2.69e-07 | 720 | 7096 | exclusion | phecode |
| 525.1 | Loss of teeth or edentulism | Digestive | 1.22 | 1.06 – 1.39 | 0.00503 | 238 | 2494 | exclusion | phecode |
| 526 | Diseases of the jaws | Digestive | 1.02 | 0.97 – 1.07 | 0.469 | 1904 | 18475 | exclusion | phecode |
| 526.1 | Cysts of the jaws | Digestive | 1.2 | 1.02 – 1.41 | 0.0316 | 159 | 1690 | exclusion | phecode |
| 526.3 | Anomalies of jaw size/symmetry | Digestive | 1.03 | 0.887 – 1.19 | 0.73 | 204 | 1904 | exclusion | phecode |
| 526.4 | Temporomandibular joint disorders | Digestive | 0.994 | 0.932 – 1.06 | 0.855 | 1083 | 10698 | exclusion | phecode |
| 526.41 | Temporomandibular joint disorder, unspecified | Digestive | 0.995 | 0.925 – 1.07 | 0.891 | 850 | 8443 | exclusion | phecode |
| 526.42 | Arthralgia/ankylosis of temporomandibular joint | Digestive | 0.939 | 0.858 – 1.03 | 0.176 | 540 | 5402 | exclusion | phecode |
| 526.5 | Inflammatory conditions of jaw | Digestive | 1.17 | 1.01 – 1.36 | 0.0376 | 194 | 1906 | exclusion | phecode |
| 526.8 | Exostosis of jaw | Digestive | 0.79 | 0.564 – 1.11 | 0.171 | 37 | 331 | exclusion | phecode |
| 526.9 | Jaw disease NOS | Digestive | 0.989 | 0.882 – 1.11 | 0.845 | 344 | 3237 | exclusion | phecode |
| 527 | Diseases of the salivary glands | Digestive | 1 | 0.941 – 1.07 | 0.933 | 1103 | 11373 | exclusion | phecode |
| 527.1 | Hypertrophy of salivary gland | Digestive | 0.924 | 0.669 – 1.28 | 0.633 | 37 | 365 | exclusion | phecode |
| 527.2 | Sialoadenitis | Digestive | 1.07 | 0.937 – 1.22 | 0.314 | 239 | 2615 | exclusion | phecode |
| 527.7 | Disturbance of salivary secretion | Digestive | 0.959 | 0.878 – 1.05 | 0.349 | 570 | 5886 | exclusion | phecode |
| 527.8 | Other specified diseases of the salivary glands | Digestive | 0.989 | 0.841 – 1.16 | 0.896 | 158 | 1554 | exclusion | phecode |
| 528 |
Diseases of the oral soft tissues, excludingDiseases of the oral soft tissues, excluding lesions specific for gingiva and tongue
|
Digestive | 1 | 0.953 – 1.05 | 0.921 | 1753 | 17405 | exclusion | phecode |
| 528.1 | Stomatitis and mucositis | Digestive | 0.957 | 0.866 – 1.06 | 0.39 | 442 | 4484 | exclusion | phecode |
| 528.11 | Stomatitis and mucositis (ulcerative) | Digestive | 1.02 | 0.856 – 1.22 | 0.821 | 137 | 1389 | exclusion | phecode |
| 528.12 | Oral aphthae | Digestive | 0.898 | 0.757 – 1.06 | 0.215 | 153 | 1544 | exclusion | phecode |
| 528.3 | Cellulitis and abscess of oral soft tissues | Digestive | 1.19 | 1 – 1.41 | 0.0437 | 158 | 1598 | exclusion | phecode |
| 528.4 | Cysts of oral soft tissues | Digestive | 0.991 | 0.787 – 1.25 | 0.938 | 83 | 835 | exclusion | phecode |
| 528.41 | Cyst of the salivary gland | Digestive | 1.03 | 0.79 – 1.34 | 0.827 | 56 | 514 | exclusion | phecode |
| 528.5 | Diseases of lips | Digestive | 0.991 | 0.878 – 1.12 | 0.889 | 311 | 2988 | exclusion | phecode |
| 528.6 | Leukoplakia of oral mucosa | Digestive | 1.22 | 0.958 – 1.56 | 0.107 | 71 | 880 | exclusion | phecode |
| 528.7 | Sialolithiasis | Digestive | 1.11 | 0.915 – 1.35 | 0.284 | 104 | 1122 | exclusion | phecode |
| 529 | Diseases and other conditions of the tongue | Digestive | 1.02 | 0.928 – 1.13 | 0.626 | 446 | 4462 | exclusion | phecode |
| 529.1 | Glossitis | Digestive | 0.882 | 0.706 – 1.1 | 0.269 | 87 | 821 | exclusion | phecode |
| 529.6 | Glossodynia | Digestive | 1.2 | 0.987 – 1.46 | 0.0672 | 107 | 1077 | exclusion | phecode |
| 530 | Diseases of esophagus | Digestive | 1.05 | 1.02 – 1.08 | 0.000117 | 10645 | 19761 | exclusion | phecode |
| 530.1 | Esophagitis, GERD and related diseases | Digestive | 1.05 | 1.03 – 1.08 | 6.43e-05 | 10344 | 19761 | exclusion | phecode |
| 530.11 | GERD | Digestive | 1.06 | 1.03 – 1.08 | 2.83e-05 | 10087 | 19760 | exclusion | phecode |
| 530.12 | Ulcer of esophagus | Digestive | 1.04 | 0.909 – 1.19 | 0.564 | 237 | 2625 | exclusion | phecode |
| 530.13 | Barrett's esophagus | Digestive | 1.07 | 0.964 – 1.19 | 0.2 | 384 | 4626 | exclusion | phecode |
| 530.14 | Reflux esophagitis | Digestive | 1.06 | 0.997 – 1.12 | 0.0633 | 1216 | 11663 | exclusion | phecode |
| 530.15 | Eosinophilic esophagitis | Digestive | 0.995 | 0.85 – 1.16 | 0.952 | 175 | 1652 | exclusion | phecode |
| 530.2 | Esophageal bleeding (varices/hemorrhage) | Digestive | 1.2 | 1.08 – 1.33 | 0.00064 | 399 | 4138 | exclusion | phecode |
| 530.3 | Stricture and stenosis of esophagus | Digestive | 1.02 | 0.933 – 1.12 | 0.661 | 546 | 5767 | exclusion | phecode |
| 530.5 | Disorders of esophageal motility | Digestive | 1.03 | 0.919 – 1.15 | 0.624 | 342 | 3541 | exclusion | phecode |
| 530.6 | Diverticulum of esophagus, acquired | Digestive | 0.884 | 0.688 – 1.14 | 0.338 | 74 | 716 | exclusion | phecode |
| 530.7 | Gastroesophageal laceration-hemorrhage syndrome | Digestive | 1.22 | 0.921 – 1.63 | 0.163 | 53 | 541 | exclusion | phecode |
| 530.9 | Heartburn | Digestive | 1.06 | 0.996 – 1.14 | 0.0669 | 993 | 10250 | exclusion | phecode |
| 531 | Peptic ulcer (excl. esophageal) | Digestive | 1.13 | 1.06 – 1.19 | 5.95e-05 | 1305 | 13093 | exclusion | phecode |
| 531.1 | Hemorrhage from gastrointestinal ulcer | Digestive | 0.987 | 0.862 – 1.13 | 0.854 | 240 | 2334 | exclusion | phecode |
| 531.2 | Gastric ulcer | Digestive | 1.1 | 1.02 – 1.19 | 0.0115 | 755 | 7687 | exclusion | phecode |
| 531.3 | Duodenal ulcer | Digestive | 1.03 | 0.911 – 1.17 | 0.621 | 284 | 2804 | exclusion | phecode |
| 531.4 | Peptic ulcer, site unspecified | Digestive | 1.15 | 1.05 – 1.26 | 0.0038 | 500 | 5056 | exclusion | phecode |
| 531.5 | Gastrojejunal ulcer | Digestive | 1.16 | 0.947 – 1.42 | 0.152 | 110 | 989 | exclusion | phecode |
| 532 | Dysphagia | Digestive | 1.08 | 1.04 – 1.12 | 7.72e-05 | 3458 | 18767 | exclusion | phecode |
| 535 | Gastritis and duodenitis | Digestive | 1.08 | 1.03 – 1.13 | 0.00293 | 1806 | 18035 | exclusion | phecode |
| 535.1 | Acute gastritis | Digestive | 1.08 | 1 – 1.17 | 0.0433 | 768 | 7665 | exclusion | phecode |
| 535.2 | Atrophic gastritis | Digestive | 1.01 | 0.876 – 1.16 | 0.898 | 228 | 2253 | exclusion | phecode |
| 535.6 | Duodenitis | Digestive | 1.13 | 0.98 – 1.31 | 0.0916 | 203 | 2139 | exclusion | phecode |
| 535.8 | Other specified gastritis | Digestive | 1.08 | 0.976 – 1.19 | 0.137 | 421 | 4181 | exclusion | phecode |
| 535.9 | Gastritis and duodenitis, NOS | Digestive | 1.09 | 1.02 – 1.18 | 0.0169 | 809 | 8317 | exclusion | phecode |
| 536 | Disorders of function of stomach | Digestive | 1.06 | 1.01 – 1.11 | 0.0148 | 1932 | 18509 | exclusion | phecode |
| 536.3 | Gastroparesis | Digestive | 1.06 | 0.961 – 1.16 | 0.253 | 488 | 4759 | exclusion | phecode |
| 536.7 |
Complications of gastrostomy, colostomy andComplications of gastrostomy, colostomy and enterostomy
|
Digestive | 1.18 | 1.03 – 1.34 | 0.0166 | 247 | 2663 | exclusion | phecode |
| 536.8 |
Dyspepsia and other specified disorders ofDyspepsia and other specified disorders of function of stomach
|
Digestive | 1.08 | 1.02 – 1.14 | 0.0103 | 1439 | 14087 | exclusion | phecode |
| 537 | Other disorders of stomach and duodenum | Digestive | 1.07 | 1.02 – 1.12 | 0.00625 | 2060 | 19708 | exclusion | phecode |
| 537.1 | Lesions of stomach and duodenum | Digestive | 1.23 | 0.985 – 1.53 | 0.0685 | 98 | 1021 | exclusion | phecode |
| 539 | Bariatric surgery | Digestive | 1.1 | 1.03 – 1.17 | 0.00556 | 1035 | 10467 | exclusion | phecode |
| 540 | Appendiceal conditions | Digestive | 1.02 | 0.915 – 1.14 | 0.712 | 374 | 3526 | exclusion | phecode |
| 540.1 | Appendicitis | Digestive | 0.979 | 0.87 – 1.1 | 0.72 | 323 | 3038 | exclusion | phecode |
| 540.11 | Acute appendicitis | Digestive | 0.969 | 0.851 – 1.1 | 0.638 | 269 | 2501 | exclusion | phecode |
| 550 | Abdominal hernia | Digestive | 1.02 | 0.981 – 1.05 | 0.386 | 4170 | 25282 | exclusion | phecode |
| 550.1 | Inguinal hernia | Digestive | 0.958 | 0.899 – 1.02 | 0.182 | 1104 | 10075 | exclusion | phecode |
| 550.2 | Diaphragmatic hernia | Digestive | 1.04 | 0.985 – 1.09 | 0.168 | 1718 | 16384 | exclusion | phecode |
| 550.3 | Femoral hernia | Digestive | 1.07 | 0.849 – 1.35 | 0.559 | 78 | 839 | exclusion | phecode |
| 550.4 | Umbilical hernia | Digestive | 0.968 | 0.9 – 1.04 | 0.374 | 818 | 8437 | exclusion | phecode |
| 550.5 | Ventral hernia | Digestive | 1.05 | 0.996 – 1.12 | 0.0688 | 1316 | 14058 | exclusion | phecode |
| 550.6 | Incisional hernia | Digestive | 1.1 | 1.02 – 1.19 | 0.0112 | 795 | 8355 | exclusion | phecode |
| 555 |
Inflammatory bowel disease and otherInflammatory bowel disease and other gastroenteritis and colitis
|
Digestive | 1.03 | 0.966 – 1.1 | 0.345 | 1004 | 10575 | exclusion | phecode |
| 555.1 | Regional enteritis | Digestive | 0.999 | 0.918 – 1.09 | 0.977 | 623 | 6467 | exclusion | phecode |
| 555.2 | Ulcerative colitis | Digestive | 1.03 | 0.944 – 1.12 | 0.52 | 596 | 6452 | exclusion | phecode |
| 555.21 | Ulcerative colitis (chronic) | Digestive | 0.986 | 0.881 – 1.1 | 0.813 | 347 | 3800 | exclusion | phecode |
| 556 | Ulceration of the lower GI tract | Digestive | 0.972 | 0.868 – 1.09 | 0.619 | 352 | 3935 | exclusion | phecode |
| 556.1 | Ulceration of intestine | Digestive | 0.963 | 0.855 – 1.09 | 0.542 | 308 | 3412 | exclusion | phecode |
| 556.11 |
Angiodysplasia of intestine (without mention ofAngiodysplasia of intestine (without mention of hemorrhage)
|
Digestive | 0.878 | 0.712 – 1.08 | 0.224 | 96 | 1175 | exclusion | phecode |
| 557 | Intestinal malabsorption (non-celiac) | Digestive | 1.03 | 0.972 – 1.1 | 0.297 | 1208 | 11789 | exclusion | phecode |
| 557.1 | Celiac disease | Digestive | 1.02 | 0.907 – 1.15 | 0.743 | 322 | 2941 | exclusion | phecode |
| 558 | Noninfectious gastroenteritis | Digestive | 1.04 | 0.998 – 1.09 | 0.061 | 2335 | 18239 | exclusion | phecode |
| 559 | Ileostomy status | Digestive | 1.1 | 1.01 – 1.2 | 0.0303 | 578 | 6182 | exclusion | phecode |
| 560 | Intestinal obstruction without mention of hernia | Digestive | 1.04 | 0.99 – 1.09 | 0.123 | 1882 | 16638 | exclusion | phecode |
| 560.1 | Paralytic ileus | Digestive | 1.07 | 1 – 1.15 | 0.0353 | 980 | 10002 | exclusion | phecode |
| 560.2 | Impaction of intestine | Digestive | 1.09 | 0.959 – 1.25 | 0.183 | 259 | 2594 | exclusion | phecode |
| 560.3 | Peritoneal or intestinal adhesions | Digestive | 1.13 | 0.966 – 1.32 | 0.126 | 177 | 1688 | exclusion | phecode |
| 560.4 | Other intestinal obstruction | Digestive | 1.03 | 0.97 – 1.1 | 0.3 | 1073 | 10710 | exclusion | phecode |
| 561 | Symptoms involving digestive system | Digestive | 1.05 | 1 – 1.11 | 0.046 | 1733 | 14726 | exclusion | phecode |
| 562 | Diverticulosis and diverticulitis | Digestive | 0.982 | 0.945 – 1.02 | 0.346 | 3706 | 15320 | exclusion | phecode |
| 562.1 | Diverticulosis | Digestive | 0.981 | 0.944 – 1.02 | 0.325 | 3676 | 15284 | exclusion | phecode |
| 562.2 | Diverticulitis | Digestive | 1.01 | 0.948 – 1.09 | 0.681 | 977 | 9500 | exclusion | phecode |
| 564 | Functional digestive disorders | Digestive | 1.03 | 1 – 1.06 | 0.0269 | 7520 | 19846 | exclusion | phecode |
| 564.1 | Irritable Bowel Syndrome | Digestive | 1.03 | 0.983 – 1.07 | 0.231 | 2419 | 15597 | exclusion | phecode |
| 564.9 | Personal history of diseases of digestive system | Digestive | 1.01 | 0.965 – 1.06 | 0.608 | 1978 | 17416 | exclusion | phecode |
| 565 | Anal and rectal conditions | Digestive | 1.03 | 0.98 – 1.07 | 0.268 | 2169 | 20376 | exclusion | phecode |
| 565.1 | Anal and rectal polyp | Digestive | 1.01 | 0.937 – 1.09 | 0.783 | 787 | 7786 | exclusion | phecode |
| 567 | Peritonitis and retroperitoneal infections | Digestive | 1.07 | 1 – 1.15 | 0.0486 | 874 | 8921 | exclusion | phecode |
| 568 | Other disorders of peritoneum | Digestive | 1.06 | 0.998 – 1.13 | 0.059 | 1079 | 11052 | exclusion | phecode |
| 568.1 |
Peritoneal adhesions (postoperative)Peritoneal adhesions (postoperative) (postinfection)
|
Digestive | 1.09 | 1.01 – 1.17 | 0.0321 | 774 | 8102 | exclusion | phecode |
| 569 | Other disorders of intestine | Digestive | 1.02 | 0.987 – 1.05 | 0.264 | 5098 | 23909 | exclusion | phecode |
| 569.1 | Toxic gastroenteritis and colitis | Digestive | 1.14 | 0.985 – 1.31 | 0.0785 | 210 | 2141 | exclusion | phecode |
| 569.2 | Gastrointestinal complications | Digestive | 1.08 | 1.01 – 1.16 | 0.0292 | 904 | 9224 | exclusion | phecode |
| 571 | Chronic liver disease and cirrhosis | Digestive | 1.04 | 0.999 – 1.08 | 0.0563 | 2957 | 21679 | exclusion | phecode |
| 571.5 | Other chronic nonalcoholic liver disease | Digestive | 1.04 | 0.995 – 1.08 | 0.0824 | 2790 | 21435 | exclusion | phecode |
| 571.51 | Cirrhosis of liver without mention of alcohol | Digestive | 1.11 | 1.03 – 1.21 | 0.0102 | 650 | 6439 | exclusion | phecode |
| 571.6 | Primary biliary cirrhosis | Digestive | 1.14 | 0.946 – 1.38 | 0.167 | 128 | 1186 | exclusion | phecode |
| 571.8 |
Liver abscess and sequelae of chronic liverLiver abscess and sequelae of chronic liver disease
|
Digestive | 1.13 | 1.04 – 1.23 | 0.00478 | 595 | 6026 | exclusion | phecode |
| 571.81 | Portal hypertension | Digestive | 1.13 | 1.01 – 1.26 | 0.0342 | 369 | 3681 | exclusion | phecode |
| 572 | Ascites (non malignant) | Digestive | 1.06 | 1.01 – 1.12 | 0.029 | 1458 | 14843 | exclusion | phecode |
| 573 | Other disorders of liver | Digestive | 1.03 | 0.995 – 1.07 | 0.0877 | 3568 | 22527 | exclusion | phecode |
| 573.1 | Chronic passive congestion of liver | Digestive | 1.07 | 0.835 – 1.36 | 0.601 | 67 | 885 | exclusion | phecode |
| 573.2 | Liver replaced by transplant | Digestive | 1.08 | 0.921 – 1.27 | 0.342 | 176 | 1857 | exclusion | phecode |
| 573.3 | Hepatomegaly | Digestive | 1.05 | 0.933 – 1.17 | 0.441 | 331 | 3120 | exclusion | phecode |
| 573.4 | Acute and subacute necrosis of liver | Digestive | 1.14 | 0.985 – 1.32 | 0.0787 | 203 | 2088 | exclusion | phecode |
| 573.5 | Jaundice (not of newborn) | Digestive | 0.995 | 0.915 – 1.08 | 0.914 | 637 | 6049 | exclusion | phecode |
| 573.6 |
Nonspecific elevation of levels of transaminaseNonspecific elevation of levels of transaminase or lactic acid dehydrogenase [LDH]
|
Digestive | 1 | 0.956 – 1.06 | 0.858 | 1769 | 17459 | exclusion | phecode |
| 573.7 | Abnormal results of function study of liver | Digestive | 1.04 | 0.99 – 1.09 | 0.12 | 1969 | 18338 | exclusion | phecode |
| 573.9 | Abnormal serum enzyme levels | Digestive | 1.01 | 0.972 – 1.05 | 0.582 | 3020 | 22785 | exclusion | phecode |
| 574 | Cholelithiasis and cholecystitis | Digestive | 0.98 | 0.936 – 1.03 | 0.393 | 2095 | 20190 | exclusion | phecode |
| 574.1 | Cholelithiasis | Digestive | 0.977 | 0.931 – 1.02 | 0.34 | 1939 | 18968 | exclusion | phecode |
| 574.11 | Cholelithiasis with acute cholecystitis | Digestive | 1.06 | 0.917 – 1.22 | 0.449 | 216 | 2226 | exclusion | phecode |
| 574.12 | Cholelithiasis with other cholecystitis | Digestive | 0.998 | 0.895 – 1.11 | 0.975 | 371 | 3599 | exclusion | phecode |
| 574.2 | Calculus of bile duct | Digestive | 1.01 | 0.921 – 1.1 | 0.882 | 574 | 5603 | exclusion | phecode |
| 574.3 | Cholecystitis without cholelithiasis | Digestive | 0.961 | 0.878 – 1.05 | 0.388 | 544 | 5329 | exclusion | phecode |
| 575 | Other biliary tract disease | Digestive | 1.02 | 0.97 – 1.08 | 0.394 | 1501 | 14707 | exclusion | phecode |
| 575.1 | Cholangitis | Digestive | 1.08 | 0.947 – 1.24 | 0.245 | 234 | 2202 | exclusion | phecode |
| 575.2 | Obstruction of bile duct | Digestive | 1.07 | 0.963 – 1.18 | 0.215 | 410 | 3833 | exclusion | phecode |
| 575.6 | Cholesterolosis of gallbladder | Digestive | 0.895 | 0.751 – 1.07 | 0.211 | 142 | 1457 | exclusion | phecode |
| 575.7 | Other disorders of gallbladder | Digestive | 0.988 | 0.909 – 1.07 | 0.775 | 636 | 6246 | exclusion | phecode |
| 575.8 | Other disorders of biliary tract | Digestive | 1.07 | 0.99 – 1.15 | 0.0899 | 757 | 7302 | exclusion | phecode |
| 575.9 |
Nonspecific abnormal findings on radiologicalNonspecific abnormal findings on radiological and other examination of biliary tract
|
Digestive | 1.24 | 1.06 – 1.45 | 0.00642 | 170 | 1683 | exclusion | phecode |
| 577 | Diseases of pancreas | Digestive | 1.09 | 1.03 – 1.15 | 0.00398 | 1408 | 14027 | exclusion | phecode |
| 577.1 | Acute pancreatitis | Digestive | 1.17 | 1.08 – 1.26 | 6.18e-05 | 791 | 7938 | exclusion | phecode |
| 577.2 | Chronic pancreatitis | Digestive | 1.16 | 1.04 – 1.31 | 0.0105 | 329 | 3218 | exclusion | phecode |
| 577.3 | Cyst and pseudocyst of pancreas | Digestive | 1.04 | 0.932 – 1.17 | 0.468 | 363 | 3392 | exclusion | phecode |
| 578 | Gastrointestinal hemorrhage | Digestive | 1.05 | 1.01 – 1.09 | 0.0215 | 2987 | 24870 | exclusion | phecode |
| 578.1 | Hematemesis | Digestive | 1.16 | 1.03 – 1.31 | 0.0116 | 319 | 3216 | exclusion | phecode |
| 578.2 | Blood in stool | Digestive | 1.06 | 1.01 – 1.11 | 0.0237 | 1763 | 17156 | exclusion | phecode |
| 578.8 | Hemorrhage of rectum and anus | Digestive | 1.05 | 0.995 – 1.11 | 0.0724 | 1474 | 14563 | exclusion | phecode |
| 578.9 | Hemorrhage of gastrointestinal tract | Digestive | 1.06 | 0.994 – 1.14 | 0.0756 | 958 | 9572 | exclusion | phecode |
| 579 | Other symptoms involving abdomen and pelvis | Digestive | 1.06 | 1.02 – 1.1 | 0.00489 | 2867 | 22847 | exclusion | phecode |
| 579.2 | Splenomegaly | Digestive | 1.09 | 0.993 – 1.2 | 0.068 | 483 | 4845 | exclusion | phecode |
| 579.8 | Nonspecific abnormal findings in stool contents | Digestive | 1.02 | 0.954 – 1.1 | 0.519 | 904 | 8763 | exclusion | phecode |
| 580 | Nephritis; nephrosis; renal sclerosis | Genitourinary | 1.06 | 0.997 – 1.13 | 0.064 | 1165 | 10082 | exclusion | phecode |
| 580.1 | Glomerulonephritis | Genitourinary | 1.02 | 0.897 – 1.16 | 0.76 | 261 | 2677 | exclusion | phecode |
| 580.11 | Proliferative glomerulonephritis | Genitourinary | 1.03 | 0.843 – 1.26 | 0.759 | 100 | 1004 | exclusion | phecode |
| 580.12 | Non-proliferative glomerulonephritis | Genitourinary | 1.16 | 0.92 – 1.47 | 0.205 | 75 | 759 | exclusion | phecode |
| 580.13 | Acute glomerulonephritis, NOS | Genitourinary | 0.968 | 0.687 – 1.36 | 0.851 | 38 | 408 | exclusion | phecode |
| 580.14 | Chronic glomerulonephritis, NOS | Genitourinary | 1.02 | 0.875 – 1.19 | 0.806 | 183 | 1825 | exclusion | phecode |
| 580.2 |
Nephrotic syndrome without mention ofNephrotic syndrome without mention of glomerulonephritis
|
Genitourinary | 1.07 | 0.905 – 1.27 | 0.418 | 154 | 1506 | exclusion | phecode |
| 580.3 |
Nephritis and nephropathy without mention ofNephritis and nephropathy without mention of glomerulonephritis
|
Genitourinary | 1.05 | 0.98 – 1.13 | 0.163 | 940 | 7767 | exclusion | phecode |
| 580.31 |
Nephritis and nephropathy in diseasesNephritis and nephropathy in diseases classified elsewhere
|
Genitourinary | 1.04 | 0.952 – 1.14 | 0.39 | 616 | 4583 | exclusion | phecode |
| 580.32 |
Nephritis and nephropathy with pathologicalNephritis and nephropathy with pathological lesion
|
Genitourinary | 1.05 | 0.947 – 1.16 | 0.37 | 426 | 4439 | exclusion | phecode |
| 580.4 | Renal sclerosis, NOS | Genitourinary | 1.06 | 0.914 – 1.22 | 0.456 | 204 | 2219 | exclusion | phecode |
| 585 | Renal failure | Genitourinary | 1.06 | 1.02 – 1.09 | 0.00179 | 4344 | 22058 | exclusion | phecode |
| 585.1 | Acute renal failure | Genitourinary | 1.07 | 1.03 – 1.12 | 0.00208 | 2460 | 18021 | exclusion | phecode |
| 585.2 | Renal failure NOS | Genitourinary | 1 | 0.914 – 1.1 | 0.922 | 492 | 5137 | exclusion | phecode |
| 585.3 | Chronic renal failure [CKD] | Genitourinary | 1.05 | 1.01 – 1.09 | 0.0115 | 3165 | 19711 | exclusion | phecode |
| 585.31 | Renal dialysis | Genitourinary | 1.03 | 0.929 – 1.13 | 0.61 | 434 | 4848 | exclusion | phecode |
| 585.32 | End stage renal disease | Genitourinary | 1.01 | 0.928 – 1.1 | 0.821 | 601 | 6414 | exclusion | phecode |
| 585.33 | Chronic Kidney Disease, Stage III | Genitourinary | 1.04 | 0.992 – 1.1 | 0.0945 | 1758 | 13388 | exclusion | phecode |
| 585.34 | Chronic Kidney Disease, Stage IV | Genitourinary | 1.03 | 0.945 – 1.13 | 0.482 | 555 | 5649 | exclusion | phecode |
| 585.4 | Chronic kidney disease, Stage I or II | Genitourinary | 1.15 | 1.06 – 1.25 | 0.000457 | 697 | 6995 | exclusion | phecode |
| 586 | Other disorders of the kidney and ureters | Genitourinary | 1.04 | 1.01 – 1.08 | 0.015 | 4649 | 23671 | exclusion | phecode |
| 586.1 | Anatomical abnormatilies of kidney and ureters | Genitourinary | 1.07 | 0.936 – 1.23 | 0.309 | 228 | 2384 | exclusion | phecode |
| 586.11 | Small kidney | Genitourinary | 1.18 | 0.988 – 1.42 | 0.0683 | 128 | 1449 | exclusion | phecode |
| 586.12 | Vesicoureteral reflux | Genitourinary | 1.03 | 0.824 – 1.28 | 0.82 | 95 | 962 | exclusion | phecode |
| 586.2 | Cyst of kidney, acquired | Genitourinary | 0.997 | 0.926 – 1.07 | 0.935 | 797 | 7759 | exclusion | phecode |
| 586.3 | Vascular disorders of kidney/hypertrophy | Genitourinary | 1.21 | 0.995 – 1.48 | 0.0561 | 114 | 1168 | exclusion | phecode |
| 586.4 | Stricture/obstruction of ureter | Genitourinary | 1.04 | 0.98 – 1.11 | 0.188 | 1102 | 10935 | exclusion | phecode |
| 587 | Kidney replaced by transpant | Genitourinary | 1 | 0.915 – 1.1 | 0.94 | 506 | 5396 | exclusion | phecode |
| 588 | Disorders resulting from impaired renal function | Genitourinary | 1.02 | 0.935 – 1.11 | 0.663 | 592 | 6037 | exclusion | phecode |
| 588.1 | Renal osteodystrophy | Genitourinary | 1.06 | 0.907 – 1.24 | 0.464 | 178 | 1894 | exclusion | phecode |
| 588.2 | Secondary hyperparathyroidism (of renal origin) | Genitourinary | 0.964 | 0.875 – 1.06 | 0.456 | 464 | 4656 | exclusion | phecode |
| 589 | Abnormal results of function study of kidney | Genitourinary | 0.964 | 0.886 – 1.05 | 0.395 | 621 | 6181 | exclusion | phecode |
| 590 | Pyelonephritis | Genitourinary | 1.09 | 1.02 – 1.17 | 0.0121 | 981 | 9817 | exclusion | phecode |
| 591 | Urinary tract infection | Genitourinary | 1.03 | 0.999 – 1.06 | 0.0617 | 6452 | 21859 | exclusion | phecode |
| 592 | Cystitis and urethritis | Genitourinary | 1.04 | 0.987 – 1.09 | 0.147 | 1968 | 16146 | exclusion | phecode |
| 592.1 | Cystitis | Genitourinary | 1.03 | 0.983 – 1.09 | 0.202 | 1861 | 15504 | exclusion | phecode |
| 592.11 | Acute cystitis | Genitourinary | 0.998 | 0.937 – 1.06 | 0.94 | 1148 | 10847 | exclusion | phecode |
| 592.12 | Chronic cystitis | Genitourinary | 1.07 | 0.903 – 1.26 | 0.449 | 153 | 1487 | exclusion | phecode |
| 592.13 | Chronic interstitial cystitis | Genitourinary | 1.14 | 1.01 – 1.28 | 0.0367 | 304 | 3098 | exclusion | phecode |
| 592.2 | Urethritis and urethral syndrome | Genitourinary | 1.12 | 0.94 – 1.33 | 0.206 | 142 | 1442 | exclusion | phecode |
| 593 | Hematuria | Genitourinary | 1.04 | 0.997 – 1.08 | 0.0743 | 3082 | 21508 | exclusion | phecode |
| 593.1 | Gross hematuria | Genitourinary | 1.04 | 0.971 – 1.11 | 0.264 | 952 | 8934 | exclusion | phecode |
| 593.2 | Microscopic hematuria | Genitourinary | 1.01 | 0.93 – 1.09 | 0.857 | 691 | 6576 | exclusion | phecode |
| 594 | Urinary calculus | Genitourinary | 1.04 | 1.01 – 1.07 | 0.0221 | 4472 | 25596 | exclusion | phecode |
| 594.1 | Calculus of kidney | Genitourinary | 1.04 | 1 – 1.07 | 0.0361 | 4190 | 25480 | exclusion | phecode |
| 594.2 | Calculus of lower urinary tract | Genitourinary | 1.04 | 0.908 – 1.2 | 0.552 | 238 | 2062 | exclusion | phecode |
| 594.3 | Calculus of ureter | Genitourinary | 1.02 | 0.95 – 1.09 | 0.646 | 953 | 8838 | exclusion | phecode |
| 594.8 | Renal colic | Genitourinary | 1.08 | 0.951 – 1.24 | 0.227 | 260 | 2488 | exclusion | phecode |
| 595 | Hydronephrosis | Genitourinary | 1.03 | 0.967 – 1.1 | 0.35 | 1095 | 10603 | exclusion | phecode |
| 596 | Other disorders of bladder | Genitourinary | 1.05 | 1 – 1.11 | 0.0347 | 1868 | 17722 | exclusion | phecode |
| 596.1 | Bladder neck obstruction | Genitourinary | 0.983 | 0.852 – 1.13 | 0.812 | 217 | 2094 | exclusion | phecode |
| 596.5 | Functional disorders of bladder | Genitourinary | 1.05 | 0.984 – 1.12 | 0.145 | 1094 | 10889 | exclusion | phecode |
| 597 | Other disorders of urethra and urinary tract | Genitourinary | 1.01 | 0.936 – 1.09 | 0.792 | 752 | 7444 | exclusion | phecode |
| 597.1 | Urethral stricture (not specified as infectious) | Genitourinary | 0.964 | 0.867 – 1.07 | 0.5 | 397 | 3872 | exclusion | phecode |
| 597.2 | Urinary complications NEC | Genitourinary | 1.01 | 0.931 – 1.1 | 0.788 | 645 | 6427 | exclusion | phecode |
| 597.8 | Urethral hypermobility/ISD | Genitourinary | 1.13 | 0.931 – 1.38 | 0.215 | 118 | 1199 | exclusion | phecode |
| 598 | Abnormal findings on examination of urine | Genitourinary | 0.963 | 0.762 – 1.22 | 0.755 | 82 | 827 | exclusion | phecode |
| 598.4 | Other cells and casts in urine | Genitourinary | 0.97 | 0.758 – 1.24 | 0.809 | 74 | 713 | exclusion | phecode |
| 599 | Other symptoms/disorders or the urinary system | Genitourinary | 1 | 0.978 – 1.03 | 0.796 | 9158 | 21191 | exclusion | phecode |
| 599.1 | Urinary obstruction | Genitourinary | 1.02 | 0.921 – 1.13 | 0.722 | 433 | 3787 | exclusion | phecode |
| 599.2 | Retention of urine | Genitourinary | 1.01 | 0.967 – 1.05 | 0.765 | 3053 | 19116 | exclusion | phecode |
| 599.3 | Dysuria | Genitourinary | 0.997 | 0.958 – 1.04 | 0.888 | 3003 | 18884 | exclusion | phecode |
| 599.4 | Urinary incontinence | Genitourinary | 1.04 | 1 – 1.08 | 0.0264 | 3590 | 18043 | exclusion | phecode |
| 599.5 | Frequency of urination and polyuria | Genitourinary | 0.997 | 0.96 – 1.03 | 0.869 | 3492 | 19505 | exclusion | phecode |
| 599.6 | Oliguria and anuria | Genitourinary | 1.11 | 0.991 – 1.25 | 0.0698 | 353 | 3571 | exclusion | phecode |
| 599.7 | Urethral discharge | Genitourinary | 0.885 | 0.686 – 1.14 | 0.343 | 74 | 711 | exclusion | phecode |
| 599.8 | Other symptoms involving urinary system | Genitourinary | 1.01 | 0.969 – 1.05 | 0.713 | 3364 | 18869 | exclusion | phecode |
| 599.9 | Other abnormality of urination | Genitourinary | 0.994 | 0.948 – 1.04 | 0.818 | 1965 | 16410 | exclusion | phecode |
| 600 | Hyperplasia of prostate | Genitourinary | 0.935 | 0.886 – 0.986 | 0.0136 | 2108 | 6918 | exclusion | phecode |
| 601 | Inflammatory diseases of prostate | Genitourinary | 0.875 | 0.807 – 0.95 | 0.00136 | 675 | 5907 | exclusion | phecode |
| 601.1 | Prostatitis | Genitourinary | 0.83 | 0.735 – 0.938 | 0.00291 | 297 | 2613 | exclusion | phecode |
| 601.11 | Acute prostatitis | Genitourinary | 1.01 | 0.797 – 1.28 | 0.94 | 79 | 697 | exclusion | phecode |
| 601.12 | Chronic prostatitis | Genitourinary | 0.681 | 0.52 – 0.894 | 0.00553 | 62 | 541 | exclusion | phecode |
| 601.3 | Orchitis and epididymitis | Genitourinary | 0.95 | 0.837 – 1.08 | 0.43 | 276 | 2433 | exclusion | phecode |
| 601.4 | Balanoposthitis | Genitourinary | 0.915 | 0.724 – 1.16 | 0.455 | 70 | 716 | exclusion | phecode |
| 601.8 |
Other inflammatory disorders of male genitalOther inflammatory disorders of male genital organs
|
Genitourinary | 0.982 | 0.805 – 1.2 | 0.86 | 106 | 952 | exclusion | phecode |
| 602 | Other disorders of prostate | Genitourinary | 0.782 | 0.673 – 0.908 | 0.00129 | 206 | 1773 | exclusion | phecode |
| 602.3 | Dysplasia of prostate | Genitourinary | 0.697 | 0.499 – 0.973 | 0.0339 | 45 | 359 | exclusion | phecode |
| 603 | Other disorders of testis | Genitourinary | 1.04 | 0.918 – 1.18 | 0.541 | 279 | 2728 | exclusion | phecode |
| 603.1 | Hydrocele | Genitourinary | 1 | 0.856 – 1.18 | 0.953 | 168 | 1746 | exclusion | phecode |
| 603.2 | Spermatocele | Genitourinary | 1.17 | 0.956 – 1.44 | 0.127 | 113 | 968 | exclusion | phecode |
| 604 | Disorders of penis | Genitourinary | 0.977 | 0.883 – 1.08 | 0.648 | 420 | 4077 | exclusion | phecode |
| 604.1 | Redundant prepuce and phimosis/BXO | Genitourinary | 1.09 | 0.873 – 1.37 | 0.434 | 78 | 852 | exclusion | phecode |
| 604.3 | Peyronie's disease | Genitourinary | 1.09 | 0.908 – 1.3 | 0.368 | 136 | 1283 | exclusion | phecode |
| 605 | Erectile dysfunction [ED] | Genitourinary | 0.946 | 0.901 – 0.994 | 0.029 | 2223 | 7925 | exclusion | phecode |
| 608 | Other disorders of male genital organs | Genitourinary | 0.98 | 0.919 – 1.05 | 0.542 | 1083 | 8865 | exclusion | phecode |
| 609 | Male infertility and abnormal spermatozoa | Genitourinary | 0.841 | 0.748 – 0.946 | 0.0038 | 329 | 2986 | exclusion | phecode |
| 609.1 | Infertility, male | Genitourinary | 0.83 | 0.726 – 0.948 | 0.00604 | 250 | 2265 | exclusion | phecode |
| 609.11 | Azoospermia and oligospermia | Genitourinary | 0.952 | 0.752 – 1.21 | 0.686 | 79 | 733 | exclusion | phecode |
| 609.2 | Abnormal spermatozoa | Genitourinary | 0.81 | 0.66 – 0.995 | 0.0443 | 107 | 994 | exclusion | phecode |
| 610 | Benign mammary dysplasias | Genitourinary | 0.915 | 0.875 – 0.957 | 9.79e-05 | 2535 | 11940 | exclusion | phecode |
| 610.1 | Cystic mastopathy | Genitourinary | 0.914 | 0.859 – 0.973 | 0.00475 | 1163 | 9883 | exclusion | phecode |
| 610.2 | Fibroadenosis of breast | Genitourinary | 0.698 | 0.514 – 0.947 | 0.0211 | 46 | 436 | exclusion | phecode |
| 610.4 | Benign neoplasm of breast | Genitourinary | 0.905 | 0.861 – 0.951 | 9.05e-05 | 1939 | 11835 | exclusion | phecode |
| 610.8 | Other specified benign mammary dysplasias | Genitourinary | 0.926 | 0.864 – 0.994 | 0.0328 | 910 | 8480 | exclusion | phecode |
| 611 | Abnormal findings on mammogram or breast exam | Genitourinary | 0.94 | 0.906 – 0.975 | 0.000854 | 4209 | 13221 | exclusion | phecode |
| 611.1 | Abnormal mammogram | Genitourinary | 0.924 | 0.888 – 0.962 | 0.000115 | 3431 | 11370 | exclusion | phecode |
| 611.11 | Mammographic microcalcification | Genitourinary | 0.877 | 0.811 – 0.947 | 0.000858 | 762 | 6945 | exclusion | phecode |
| 611.3 | Lump or mass in breast | Genitourinary | 0.958 | 0.917 – 1 | 0.06 | 2495 | 13175 | exclusion | phecode |
| 612 |
Breast conditions, congenital or relating toBreast conditions, congenital or relating to hormones
|
Genitourinary | 0.967 | 0.894 – 1.05 | 0.394 | 740 | 7503 | exclusion | phecode |
| 612.1 | Galactorrhea | Genitourinary | 0.932 | 0.77 – 1.13 | 0.467 | 112 | 1066 | exclusion | phecode |
| 612.2 | Hypertrophy of breast (Gynecomastia) | Genitourinary | 0.977 | 0.891 – 1.07 | 0.616 | 544 | 5607 | exclusion | phecode |
| 612.3 | Congenital anomalies of breast | Genitourinary | 0.855 | 0.661 – 1.11 | 0.232 | 67 | 608 | exclusion | phecode |
| 613 | Other nonmalignant breast conditions | Genitourinary | 0.985 | 0.944 – 1.03 | 0.48 | 2687 | 15669 | exclusion | phecode |
| 613.1 | Inflammatory disease of breast | Genitourinary | 1.01 | 0.914 – 1.12 | 0.799 | 410 | 4207 | exclusion | phecode |
| 613.5 | Mastodynia | Genitourinary | 1.02 | 0.959 – 1.09 | 0.513 | 1146 | 11341 | exclusion | phecode |
| 613.7 | Other signs and symptoms in breast | Genitourinary | 0.988 | 0.908 – 1.07 | 0.771 | 618 | 6226 | exclusion | phecode |
| 613.8 | Other specified disorders of breast | Genitourinary | 0.991 | 0.912 – 1.08 | 0.84 | 643 | 6546 | exclusion | phecode |
| 613.9 | Breast disorder NOS | Genitourinary | 0.963 | 0.901 – 1.03 | 0.272 | 1003 | 9628 | exclusion | phecode |
| 614 | Inflammatory diseases of female pelvic organs | Genitourinary | 1 | 0.962 – 1.05 | 0.857 | 2756 | 13918 | exclusion | phecode |
| 614.1 |
Pelvic peritoneal adhesions, femalePelvic peritoneal adhesions, female (postoperative) (postinfection)
|
Genitourinary | 0.867 | 0.755 – 0.995 | 0.0418 | 231 | 2452 | exclusion | phecode |
| 614.3 | Pelvic inflammatory disease (PID) | Genitourinary | 1.05 | 0.937 – 1.17 | 0.427 | 357 | 3510 | exclusion | phecode |
| 614.31 | Acute inflammatory pelvic disease | Genitourinary | 0.997 | 0.784 – 1.27 | 0.984 | 74 | 715 | exclusion | phecode |
| 614.32 | Chronic inflammatory pelvic disease | Genitourinary | 0.93 | 0.777 – 1.11 | 0.429 | 135 | 1305 | exclusion | phecode |
| 614.33 | Pelvic inflammatory disease, NOS | Genitourinary | 1.16 | 0.992 – 1.35 | 0.0625 | 186 | 1835 | exclusion | phecode |
| 614.4 | Inflammatory diseases of uterus, except cervix | Genitourinary | 1.11 | 0.924 – 1.34 | 0.261 | 130 | 1257 | exclusion | phecode |
| 614.5 |
Inflammatory disease of cervix, vagina, andInflammatory disease of cervix, vagina, and vulva
|
Genitourinary | 1.01 | 0.968 – 1.06 | 0.586 | 2381 | 13855 | exclusion | phecode |
| 614.51 | Cervicitis and endocervicitis | Genitourinary | 1.03 | 0.891 – 1.2 | 0.659 | 198 | 1951 | exclusion | phecode |
| 614.52 | Vaginitis and vulvovaginitis | Genitourinary | 1.01 | 0.958 – 1.06 | 0.819 | 2047 | 13489 | exclusion | phecode |
| 614.53 | Cyst or abscess of Bartholin's gland | Genitourinary | 1.06 | 0.856 – 1.31 | 0.6 | 99 | 970 | exclusion | phecode |
| 614.54 | Abscess or ulceration of vulva | Genitourinary | 0.974 | 0.833 – 1.14 | 0.737 | 175 | 1590 | exclusion | phecode |
| 615 | Endometriosis | Genitourinary | 0.996 | 0.936 – 1.06 | 0.887 | 1188 | 10561 | exclusion | phecode |
| 618 | Genital prolapse | Genitourinary | 1.03 | 0.972 – 1.09 | 0.326 | 1393 | 12353 | exclusion | phecode |
| 618.1 | Prolapse of vaginal walls | Genitourinary | 1.04 | 0.968 – 1.11 | 0.296 | 936 | 8997 | exclusion | phecode |
| 618.2 | Uterine/Uterovaginal prolapse | Genitourinary | 0.997 | 0.89 – 1.12 | 0.962 | 361 | 3599 | exclusion | phecode |
| 618.5 | Prolapse of vaginal vault after hysterectomy | Genitourinary | 0.985 | 0.853 – 1.14 | 0.832 | 215 | 2017 | exclusion | phecode |
| 618.6 | Vaginal enterocele, congenital or acquired | Genitourinary | 1.05 | 0.93 – 1.19 | 0.417 | 294 | 2921 | exclusion | phecode |
| 619 | Noninflammatory female genital disorders | Genitourinary | 1.01 | 0.971 – 1.04 | 0.718 | 4260 | 13203 | exclusion | phecode |
| 619.1 |
Noninflammatory disorders of ovary, fallopianNoninflammatory disorders of ovary, fallopian tube, and broad ligament
|
Genitourinary | 0.969 | 0.904 – 1.04 | 0.372 | 937 | 8900 | exclusion | phecode |
| 619.2 | Disorders of uterus, NEC | Genitourinary | 1.02 | 0.92 – 1.12 | 0.763 | 452 | 4217 | exclusion | phecode |
| 619.3 | Noninflammatory disorders of cervix | Genitourinary | 1.02 | 0.908 – 1.13 | 0.788 | 362 | 3449 | exclusion | phecode |
| 619.4 | Noninflammatory disorders of vagina | Genitourinary | 1.04 | 0.991 – 1.09 | 0.107 | 1910 | 13024 | exclusion | phecode |
| 619.5 | Noninflammatory disorders of vulva and perineum | Genitourinary | 1.01 | 0.943 – 1.09 | 0.719 | 863 | 8269 | exclusion | phecode |
| 620 | Dysplasia of female genital organs | Genitourinary | 1.05 | 0.928 – 1.18 | 0.444 | 296 | 2803 | exclusion | phecode |
| 620.1 | Dysplasia of cervix | Genitourinary | 0.95 | 0.795 – 1.14 | 0.575 | 139 | 1300 | exclusion | phecode |
| 621 | Endometrial hyperplasia | Genitourinary | 0.934 | 0.829 – 1.05 | 0.256 | 323 | 3085 | exclusion | phecode |
| 622 | Polyp of female genital organs | Genitourinary | 0.946 | 0.887 – 1.01 | 0.0882 | 1095 | 9880 | exclusion | phecode |
| 622.1 | Polyp of corpus uteri | Genitourinary | 0.949 | 0.883 – 1.02 | 0.161 | 861 | 7762 | exclusion | phecode |
| 622.2 | Mucous polyp of cervix | Genitourinary | 0.861 | 0.767 – 0.967 | 0.0113 | 332 | 3060 | exclusion | phecode |
| 623 | Hypertrophy of female genital organs | Genitourinary | 1.02 | 0.933 – 1.11 | 0.696 | 604 | 5734 | exclusion | phecode |
| 624 | Symptoms involving female genital tract | Genitourinary | 1.06 | 0.989 – 1.13 | 0.103 | 1030 | 9127 | exclusion | phecode |
| 624.1 | Dystrophy of female genital tract | Genitourinary | 0.939 | 0.79 – 1.12 | 0.473 | 144 | 1422 | exclusion | phecode |
| 624.2 | Atrophy of female genital tract | Genitourinary | 0.769 | 0.543 – 1.09 | 0.139 | 38 | 432 | exclusion | phecode |
| 624.9 | stress incontinence, female | Genitourinary | 1.07 | 1 – 1.13 | 0.0348 | 1324 | 10579 | exclusion | phecode |
| 625 |
Pain and other symptoms associated with femalePain and other symptoms associated with female genital organs
|
Genitourinary | 1.02 | 0.983 – 1.06 | 0.295 | 4188 | 12277 | exclusion | phecode |
| 625.1 | Dyspareunia | Genitourinary | 1.05 | 0.976 – 1.12 | 0.198 | 922 | 9079 | exclusion | phecode |
| 626 |
Disorders of menstruation and other abnormalDisorders of menstruation and other abnormal bleeding from female genital tract
|
Genitourinary | 0.977 | 0.942 – 1.01 | 0.21 | 4566 | 10921 | exclusion | phecode |
| 626.1 | Irregular menstrual cycle/bleeding | Genitourinary | 0.972 | 0.934 – 1.01 | 0.178 | 3351 | 10337 | exclusion | phecode |
| 626.11 | Absent or infrequent menstruation | Genitourinary | 0.991 | 0.921 – 1.07 | 0.813 | 852 | 6548 | exclusion | phecode |
| 626.12 | Excessive or frequent menstruation | Genitourinary | 0.952 | 0.901 – 1 | 0.0743 | 1639 | 8764 | exclusion | phecode |
| 626.13 | Irregular menstrual cycle | Genitourinary | 0.972 | 0.919 – 1.03 | 0.327 | 1522 | 8915 | exclusion | phecode |
| 626.14 | Irregular menstrual bleeding | Genitourinary | 0.958 | 0.887 – 1.04 | 0.278 | 758 | 6695 | exclusion | phecode |
| 626.15 | Infertility, female, associated with anovulation | Genitourinary | 0.993 | 0.883 – 1.12 | 0.902 | 311 | 2910 | exclusion | phecode |
| 626.2 | Dysmenorrhea | Genitourinary | 0.994 | 0.93 – 1.06 | 0.846 | 1078 | 7408 | exclusion | phecode |
| 626.4 | Premenstrual tension syndromes | Genitourinary | 1.02 | 0.891 – 1.17 | 0.783 | 252 | 2457 | exclusion | phecode |
| 626.8 | Infertility, female | Genitourinary | 0.887 | 0.815 – 0.964 | 0.0048 | 649 | 5153 | exclusion | phecode |
| 627 | Menopausal and postmenopausal disorders | Genitourinary | 0.97 | 0.93 – 1.01 | 0.149 | 3149 | 9976 | exclusion | phecode |
| 627.1 | Postmenopausal bleeding | Genitourinary | 0.98 | 0.906 – 1.06 | 0.602 | 775 | 6692 | exclusion | phecode |
| 627.2 | Symptomatic menopause | Genitourinary | 0.951 | 0.905 – 1 | 0.0481 | 2079 | 9308 | exclusion | phecode |
| 627.21 | Symptomatic artificial menopause | Genitourinary | 0.928 | 0.764 – 1.13 | 0.448 | 112 | 1062 | exclusion | phecode |
| 627.22 |
Need for Hormone replacement therapyNeed for Hormone replacement therapy (postmenopausal)
|
Genitourinary | 0.878 | 0.761 – 1.01 | 0.0749 | 219 | 2218 | exclusion | phecode |
| 627.3 | Postmenopausal atrophic vaginitis | Genitourinary | 0.922 | 0.847 – 1 | 0.0577 | 656 | 6115 | exclusion | phecode |
| 627.4 | Premenopausal menorrhagia | Genitourinary | 0.938 | 0.823 – 1.07 | 0.342 | 261 | 2564 | exclusion | phecode |
| 627.5 | Premature menopause and other ovarian failure | Genitourinary | 0.88 | 0.767 – 1.01 | 0.0689 | 230 | 2276 | exclusion | phecode |
| 628 | Ovarian cyst | Genitourinary | 0.956 | 0.904 – 1.01 | 0.117 | 1474 | 9849 | exclusion | phecode |
| 634 | Miscarriage; stillbirth | Pregnancy Complications | 0.994 | 0.915 – 1.08 | 0.896 | 626 | 6182 | exclusion | phecode |
| 634.1 | Missed abortion/Hydatidiform mole | Pregnancy Complications | 0.891 | 0.774 – 1.03 | 0.108 | 221 | 2130 | exclusion | phecode |
| 634.3 | Ectopic pregnancy | Pregnancy Complications | 1.26 | 1.01 – 1.56 | 0.0398 | 88 | 910 | exclusion | phecode |
| 635 |
Hemorrhage during pregnancy; childbirth andHemorrhage during pregnancy; childbirth and postpartum
|
Pregnancy Complications | 0.984 | 0.892 – 1.09 | 0.745 | 450 | 4234 | exclusion | phecode |
| 635.2 |
Antepartum hemorrhage, abruptio placentae, andAntepartum hemorrhage, abruptio placentae, and placenta previa
|
Pregnancy Complications | 1 | 0.886 – 1.13 | 0.994 | 298 | 2898 | exclusion | phecode |
| 635.3 | Placenta previa and abruptio placenta | Pregnancy Complications | 0.924 | 0.804 – 1.06 | 0.262 | 225 | 2295 | exclusion | phecode |
| 636 |
Early or threatened labor; hemorrhage in earlyEarly or threatened labor; hemorrhage in early pregnancy
|
Pregnancy Complications | 1.02 | 0.95 – 1.1 | 0.567 | 861 | 6238 | exclusion | phecode |
| 636.1 | Threatened premature labor | Pregnancy Complications | 1.07 | 0.95 – 1.2 | 0.27 | 308 | 3041 | exclusion | phecode |
| 636.2 | Early onset of delivery | Pregnancy Complications | 1 | 0.871 – 1.15 | 0.986 | 229 | 2261 | exclusion | phecode |
| 636.3 | Hemorrhage in early pregnancy | Pregnancy Complications | 1.01 | 0.904 – 1.13 | 0.865 | 355 | 3446 | exclusion | phecode |
| 636.8 | Cervical incompetence | Pregnancy Complications | 1.15 | 0.881 – 1.5 | 0.305 | 61 | 623 | exclusion | phecode |
| 637 |
Short gestation; low birth weight; and fetalShort gestation; low birth weight; and fetal growth retardation
|
Pregnancy Complications | 1.17 | 0.92 – 1.5 | 0.197 | 71 | 635 | exclusion | phecode |
| 642 |
Hypertension complicating pregnancyHypertension complicating pregnancy, childbirth, and the puerperium
|
Pregnancy Complications | 0.995 | 0.901 – 1.1 | 0.916 | 444 | 4475 | exclusion | phecode |
| 642.1 | Preeclampsia and eclampsia | Pregnancy Complications | 1.02 | 0.886 – 1.16 | 0.824 | 234 | 2349 | exclusion | phecode |
| 643 | Excessive vomiting in pregnancy | Pregnancy Complications | 0.953 | 0.825 – 1.1 | 0.512 | 213 | 2000 | exclusion | phecode |
| 643.1 | Hyperemesis gravidarum | Pregnancy Complications | 0.97 | 0.787 – 1.2 | 0.777 | 101 | 944 | exclusion | phecode |
| 644 | Anemia during pregnancy | Pregnancy Complications | 0.947 | 0.81 – 1.11 | 0.492 | 176 | 1798 | exclusion | phecode |
| 646 | Other complications of pregnancy NEC | Pregnancy Complications | 1.03 | 0.953 – 1.12 | 0.427 | 676 | 5250 | exclusion | phecode |
| 647 |
Infectious and parasitic complicationsInfectious and parasitic complications affecting pregnancy
|
Pregnancy Complications | 1.06 | 0.907 – 1.25 | 0.451 | 167 | 1668 | exclusion | phecode |
| 647.1 |
Infections of genitourinary tract duringInfections of genitourinary tract during pregnancy
|
Pregnancy Complications | 1.1 | 0.941 – 1.29 | 0.228 | 172 | 1791 | exclusion | phecode |
| 647.3 | Major puerperal infection | Pregnancy Complications | 1.09 | 0.812 – 1.46 | 0.569 | 53 | 527 | exclusion | phecode |
| 649 |
Other conditions or status of the motherOther conditions or status of the mother complicating pregnancy, childbirth, or the puerperium
|
Pregnancy Complications | 0.957 | 0.894 – 1.02 | 0.209 | 993 | 6385 | exclusion | phecode |
| 649.1 |
Diabetes or abnormal glucose toleranceDiabetes or abnormal glucose tolerance complicating pregnancy
|
Pregnancy Complications | 0.988 | 0.897 – 1.09 | 0.802 | 481 | 4349 | exclusion | phecode |
| 653 |
Problems associated with amniotic cavity andProblems associated with amniotic cavity and membranes
|
Pregnancy Complications | 0.991 | 0.9 – 1.09 | 0.859 | 466 | 4336 | exclusion | phecode |
| 654.1 |
Abnormality of organs and soft tissues ofAbnormality of organs and soft tissues of pelvis complicating pregnancy, childbirth, or the puerperium
|
Pregnancy Complications | 1 | 0.855 – 1.18 | 0.961 | 174 | 1634 | exclusion | phecode |
| 654.2 | Rhesus isoimmunization in pregnancy | Pregnancy Complications | 1.07 | 0.911 – 1.27 | 0.394 | 152 | 1644 | exclusion | phecode |
| 655 |
Known or suspected fetal abnormality affectingKnown or suspected fetal abnormality affecting management of mother
|
Pregnancy Complications | 0.944 | 0.888 – 1 | 0.0605 | 1295 | 7888 | exclusion | phecode |
| 655.1 | Abnormality in fetal heart rate or rhythm | Pregnancy Complications | 0.947 | 0.861 – 1.04 | 0.259 | 492 | 4405 | exclusion | phecode |
| 656 | Other perinatal conditions of fetus or newborn | Pregnancy Complications | 1.04 | 0.962 – 1.13 | 0.314 | 691 | 5494 | exclusion | phecode |
| 656.2 | Respiratory conditions of fetus and newborn | Pregnancy Complications | 1.05 | 0.757 – 1.44 | 0.787 | 47 | 448 | exclusion | phecode |
| 669 | Complications of labor and delivery NEC | Pregnancy Complications | 0.936 | 0.864 – 1.01 | 0.106 | 710 | 5413 | exclusion | phecode |
| 671 |
Venous/cerebrovascular complications embolismVenous/cerebrovascular complications embolism in pregnancy and the puerperium
|
Pregnancy Complications | 0.971 | 0.826 – 1.14 | 0.725 | 170 | 1796 | exclusion | phecode |
| 674 | Other complications of the puerperium NEC | Pregnancy Complications | 1.06 | 0.886 – 1.27 | 0.513 | 132 | 1258 | exclusion | phecode |
| 676 |
Other disorders of the breast associated withOther disorders of the breast associated with childbirth and disorders of lactation
|
Pregnancy Complications | 0.966 | 0.807 – 1.16 | 0.705 | 145 | 1451 | exclusion | phecode |
| 681 | Superficial cellulitis and abscess | Dermatologic | 1.06 | 1.03 – 1.1 | 0.000422 | 4270 | 25922 | exclusion | phecode |
| 681.1 | Cellulitis and abscess of fingers/toes | Dermatologic | 1.04 | 0.968 – 1.12 | 0.266 | 844 | 7561 | exclusion | phecode |
| 681.2 | Cellulitis and abscess of face/neck | Dermatologic | 1.09 | 1.01 – 1.19 | 0.0307 | 651 | 6634 | exclusion | phecode |
| 681.3 | Cellulitis and abscess of arm/hand | Dermatologic | 1.07 | 1.01 – 1.13 | 0.0259 | 1371 | 12926 | exclusion | phecode |
| 681.5 | Cellulitis and abscess of leg, except foot | Dermatologic | 1.06 | 1 – 1.12 | 0.0457 | 1446 | 13484 | exclusion | phecode |
| 681.6 | Cellulitis and abscess of foot, toe | Dermatologic | 1.08 | 1.02 – 1.15 | 0.015 | 1160 | 10873 | exclusion | phecode |
| 681.7 | Cellulitis and abscess of trunk | Dermatologic | 1.08 | 1.02 – 1.16 | 0.0145 | 1035 | 10377 | exclusion | phecode |
| 686 |
Other local infections of skin and subcutaneousOther local infections of skin and subcutaneous tissue
|
Dermatologic | 1.08 | 1.03 – 1.14 | 0.00364 | 1526 | 14381 | exclusion | phecode |
| 686.1 | Carbuncle and furuncle | Dermatologic | 1.1 | 0.989 – 1.22 | 0.0797 | 395 | 3884 | exclusion | phecode |
| 686.2 | Impetigo | Dermatologic | 1.05 | 0.923 – 1.19 | 0.471 | 273 | 2844 | exclusion | phecode |
| 686.3 | Pilonidal cyst | Dermatologic | 1.11 | 0.925 – 1.34 | 0.255 | 130 | 1170 | exclusion | phecode |
| 686.4 | Pyogenic granuloma | Dermatologic | 0.983 | 0.804 – 1.2 | 0.864 | 108 | 1039 | exclusion | phecode |
| 686.5 | Pyoderma | Dermatologic | 1 | 0.722 – 1.4 | 0.977 | 40 | 425 | exclusion | phecode |
| 687 | Symptoms affecting skin | Dermatologic | 1.02 | 0.957 – 1.09 | 0.515 | 1057 | 10401 | exclusion | phecode |
| 687.1 | Rash and other nonspecific skin eruption | Dermatologic | 0.99 | 0.958 – 1.02 | 0.529 | 4756 | 23284 | exclusion | phecode |
| 687.3 | Changes in skin texture | Dermatologic | 1.06 | 0.921 – 1.21 | 0.436 | 249 | 2637 | exclusion | phecode |
| 687.4 | Disturbance of skin sensation | Dermatologic | 1.06 | 1.03 – 1.1 | 0.000424 | 4349 | 22902 | exclusion | phecode |
| 689 | Disorder of skin and subcutaneous tissue NOS | Dermatologic | 0.962 | 0.934 – 0.99 | 0.00825 | 6140 | 25262 | exclusion | phecode |
| 690 | Erythematosquamous dermatosis | Dermatologic | 0.95 | 0.914 – 0.987 | 0.00789 | 3312 | 20503 | exclusion | phecode |
| 690.1 | Seborrheic dermatitis | Dermatologic | 0.949 | 0.913 – 0.986 | 0.00684 | 3305 | 20483 | exclusion | phecode |
| 691 | Congenital anomalies of skin | Dermatologic | 1.01 | 0.903 – 1.12 | 0.904 | 374 | 3705 | exclusion | phecode |
| 691.3 | Congenital pigmentary anomalies of skin | Dermatologic | 0.978 | 0.721 – 1.33 | 0.889 | 44 | 452 | exclusion | phecode |
| 694 | Dyschromia and Vitiligo | Dermatologic | 0.967 | 0.911 – 1.03 | 0.264 | 1275 | 11672 | exclusion | phecode |
| 694.1 | Vitiligo | Dermatologic | 0.883 | 0.714 – 1.09 | 0.248 | 91 | 896 | exclusion | phecode |
| 694.2 | Other dyschromia | Dermatologic | 0.972 | 0.913 – 1.03 | 0.375 | 1153 | 10519 | exclusion | phecode |
| 694.3 | Vascular disorders of skin | Dermatologic | 1.15 | 0.857 – 1.55 | 0.347 | 50 | 508 | exclusion | phecode |
| 695 | Erythematous conditions | Dermatologic | 0.965 | 0.926 – 1.01 | 0.0938 | 2688 | 19771 | exclusion | phecode |
| 695.1 | Toxic erythema | Dermatologic | 1 | 0.736 – 1.37 | 0.98 | 48 | 472 | exclusion | phecode |
| 695.2 | Bullous dermatoses | Dermatologic | 1.15 | 0.866 – 1.52 | 0.335 | 53 | 459 | exclusion | phecode |
| 695.3 | Rosacea | Dermatologic | 0.895 | 0.842 – 0.952 | 0.000441 | 1186 | 11298 | exclusion | phecode |
| 695.4 | Lupus (localized and systemic) | Dermatologic | 1.03 | 0.933 – 1.14 | 0.547 | 451 | 4635 | exclusion | phecode |
| 695.41 | Cutaneous lupus erythematosus | Dermatologic | 1.04 | 0.882 – 1.22 | 0.652 | 173 | 1741 | exclusion | phecode |
| 695.42 | Systemic lupus erythematosus | Dermatologic | 1.03 | 0.926 – 1.14 | 0.621 | 430 | 4416 | exclusion | phecode |
| 695.7 | Prurigo and Lichen | Dermatologic | 1.04 | 0.935 – 1.16 | 0.455 | 371 | 3802 | exclusion | phecode |
| 695.8 | Other specified erythematous conditions | Dermatologic | 0.935 | 0.852 – 1.03 | 0.158 | 525 | 5232 | exclusion | phecode |
| 695.81 | Erythema nodosum | Dermatologic | 0.838 | 0.615 – 1.14 | 0.264 | 44 | 389 | exclusion | phecode |
| 695.9 | Unspecified erythematous condition | Dermatologic | 1.02 | 0.925 – 1.13 | 0.645 | 426 | 4268 | exclusion | phecode |
| 696 | Psoriasis and related disorders | Dermatologic | 0.987 | 0.92 – 1.06 | 0.719 | 879 | 9085 | exclusion | phecode |
| 696.3 | Pityriasis | Dermatologic | 0.996 | 0.779 – 1.27 | 0.973 | 72 | 691 | exclusion | phecode |
| 696.4 | Psoriasis | Dermatologic | 1 | 0.929 – 1.08 | 0.981 | 806 | 8466 | exclusion | phecode |
| 696.41 | Psoriasis vulgaris | Dermatologic | 0.992 | 0.918 – 1.07 | 0.848 | 736 | 7749 | exclusion | phecode |
| 696.42 | Psoriatic arthropathy | Dermatologic | 1.06 | 0.911 – 1.24 | 0.44 | 178 | 1837 | exclusion | phecode |
| 697 | Sarcoidosis | Dermatologic | 1.12 | 0.974 – 1.3 | 0.111 | 214 | 2118 | exclusion | phecode |
| 698 | Pruritus and related conditions | Dermatologic | 1.03 | 0.972 – 1.08 | 0.359 | 1539 | 14777 | exclusion | phecode |
| 700 | Corns and callosities | Dermatologic | 1.07 | 0.999 – 1.16 | 0.0527 | 902 | 6840 | exclusion | phecode |
| 701 |
Other hypertrophic and atrophic conditions ofOther hypertrophic and atrophic conditions of skin
|
Dermatologic | 1.01 | 0.976 – 1.04 | 0.664 | 5162 | 25605 | exclusion | phecode |
| 701.1 | Keratoderma, acquired | Dermatologic | 1.1 | 0.981 – 1.23 | 0.102 | 359 | 3444 | exclusion | phecode |
| 701.2 | Scar conditions and fibrosis of skin | Dermatologic | 1.05 | 0.998 – 1.11 | 0.0573 | 1506 | 14268 | exclusion | phecode |
| 701.3 | Circumscribed scleroderma | Dermatologic | 0.891 | 0.799 – 0.993 | 0.0366 | 380 | 3786 | exclusion | phecode |
| 701.4 | Keloid scar | Dermatologic | 0.989 | 0.894 – 1.09 | 0.833 | 428 | 4021 | exclusion | phecode |
| 701.5 | Abnormal granulation tissue | Dermatologic | 0.948 | 0.833 – 1.08 | 0.425 | 253 | 2639 | exclusion | phecode |
| 702 |
Degenerative skin conditions and otherDegenerative skin conditions and other dermatoses
|
Dermatologic | 0.936 | 0.903 – 0.969 | 0.000184 | 4315 | 19109 | exclusion | phecode |
| 702.1 | Actinic keratosis | Dermatologic | 0.927 | 0.888 – 0.969 | 0.000745 | 2514 | 16269 | exclusion | phecode |
| 702.2 | Seborrheic keratosis | Dermatologic | 0.931 | 0.897 – 0.967 | 0.000226 | 3414 | 20195 | exclusion | phecode |
| 702.4 | Degenerative skin disorders | Dermatologic | 0.907 | 0.686 – 1.2 | 0.496 | 57 | 568 | exclusion | phecode |
| 703 | Diseases of nail, NOS | Dermatologic | 0.995 | 0.932 – 1.06 | 0.883 | 1067 | 9412 | exclusion | phecode |
| 703.1 | Ingrowing nail | Dermatologic | 1.01 | 0.926 – 1.1 | 0.85 | 624 | 5776 | exclusion | phecode |
| 704 | Diseases of hair and hair follicles | Dermatologic | 0.972 | 0.929 – 1.02 | 0.214 | 2193 | 20255 | exclusion | phecode |
| 704.1 | Alopecia | Dermatologic | 0.961 | 0.899 – 1.03 | 0.253 | 987 | 9714 | exclusion | phecode |
| 704.11 | Alopecia Areata | Dermatologic | 0.855 | 0.637 – 1.15 | 0.294 | 49 | 573 | exclusion | phecode |
| 704.12 | Telogen effluvium | Dermatologic | 1.05 | 0.77 – 1.43 | 0.76 | 49 | 419 | exclusion | phecode |
| 704.2 | Hirsutism | Dermatologic | 1.21 | 1.05 – 1.39 | 0.00812 | 236 | 2259 | exclusion | phecode |
| 704.8 |
Other specified diseases of hair and hairOther specified diseases of hair and hair follicles
|
Dermatologic | 1 | 0.942 – 1.06 | 0.996 | 1229 | 11561 | exclusion | phecode |
| 705 | Disorders of sweat glands | Dermatologic | 1.11 | 1 – 1.23 | 0.0454 | 430 | 4347 | exclusion | phecode |
| 705.1 | Dyshidrosis | Dermatologic | 1.3 | 1.05 – 1.6 | 0.014 | 107 | 1079 | exclusion | phecode |
| 705.3 | Hidradenitis | Dermatologic | 1.22 | 1.04 – 1.42 | 0.0145 | 176 | 1823 | exclusion | phecode |
| 705.8 | Hyperhidrosis | Dermatologic | 1.08 | 0.998 – 1.16 | 0.0572 | 743 | 7434 | exclusion | phecode |
| 706 | Diseases of sebaceous glands | Dermatologic | 0.987 | 0.954 – 1.02 | 0.43 | 4186 | 26634 | exclusion | phecode |
| 706.1 | Acne | Dermatologic | 0.954 | 0.909 – 1 | 0.0526 | 1980 | 16288 | exclusion | phecode |
| 706.2 | Sebaceous cyst | Dermatologic | 0.995 | 0.948 – 1.04 | 0.836 | 1922 | 17523 | exclusion | phecode |
| 706.3 | Seborrhea | Dermatologic | 1.23 | 0.879 – 1.73 | 0.224 | 39 | 379 | exclusion | phecode |
| 706.8 | Other specified diseases of sebaceous glands | Dermatologic | 0.997 | 0.934 – 1.07 | 0.938 | 1048 | 9384 | exclusion | phecode |
| 707 | Chronic ulcer of skin | Dermatologic | 1.13 | 1.07 – 1.19 | 1.79e-06 | 1772 | 16945 | exclusion | phecode |
| 707.1 | Decubitus ulcer | Dermatologic | 1.2 | 1.09 – 1.33 | 0.000212 | 481 | 4919 | exclusion | phecode |
| 707.2 | Chronic ulcer of leg or foot | Dermatologic | 1.08 | 0.991 – 1.17 | 0.0813 | 676 | 6210 | exclusion | phecode |
| 707.3 | Chronic ulcer of unspecified site | Dermatologic | 1.1 | 1.03 – 1.17 | 0.00426 | 1042 | 10365 | exclusion | phecode |
| 709 | Diffuse diseases of connective tissue | Dermatologic | 1.04 | 0.973 – 1.11 | 0.241 | 1014 | 9662 | exclusion | phecode |
| 709.2 | Sicca syndrome | Dermatologic | 1.01 | 0.898 – 1.13 | 0.895 | 355 | 3279 | exclusion | phecode |
| 709.3 | Systemic sclerosis | Dermatologic | 1.16 | 0.967 – 1.4 | 0.109 | 136 | 1494 | exclusion | phecode |
| 709.5 | Dermatomyositis | Dermatologic | 1 | 0.773 – 1.3 | 0.994 | 63 | 593 | exclusion | phecode |
| 709.6 |
Other specified diffuse diseases of connectiveOther specified diffuse diseases of connective tissue
|
Dermatologic | 1.13 | 0.86 – 1.48 | 0.381 | 61 | 624 | exclusion | phecode |
| 709.7 | Unspecified diffuse connective tissue disease | Dermatologic | 1.04 | 0.954 – 1.13 | 0.385 | 640 | 6177 | exclusion | phecode |
| 710 |
Osteomyelitis, periostitis, and otherOsteomyelitis, periostitis, and other infections involving bone
|
Musculoskeletal | 1.12 | 1.04 – 1.21 | 0.00188 | 803 | 7785 | exclusion | phecode |
| 710.1 | Osteomyelitis | Musculoskeletal | 1.11 | 1.03 – 1.2 | 0.00623 | 767 | 7455 | exclusion | phecode |
| 710.11 | Acute osteomyelitis | Musculoskeletal | 1.15 | 1.03 – 1.28 | 0.01 | 372 | 3689 | exclusion | phecode |
| 710.12 | Chronic osteomyelitis | Musculoskeletal | 1.15 | 1.03 – 1.29 | 0.0123 | 354 | 3352 | exclusion | phecode |
| 710.19 | Unspecified osteomyelitis | Musculoskeletal | 1.12 | 1.04 – 1.21 | 0.00422 | 743 | 7165 | exclusion | phecode |
| 711 | Arthropathy associated with infections | Musculoskeletal | 1.12 | 0.983 – 1.28 | 0.0886 | 258 | 2644 | exclusion | phecode |
| 711.1 | Pyogenic arthritis | Musculoskeletal | 1.08 | 0.924 – 1.26 | 0.344 | 181 | 1846 | exclusion | phecode |
| 712 | Infective connective tissue disorders | Musculoskeletal | 1.07 | 0.879 – 1.3 | 0.51 | 110 | 1107 | exclusion | phecode |
| 713 |
Arthropathy associated with other disordersArthropathy associated with other disorders classified elsewhere
|
Musculoskeletal | 1.07 | 0.928 – 1.24 | 0.335 | 201 | 2047 | exclusion | phecode |
| 713.5 |
Arthropathy associated with neurologicalArthropathy associated with neurological disorders
|
Musculoskeletal | 1.05 | 0.868 – 1.27 | 0.617 | 121 | 1142 | exclusion | phecode |
| 714 |
Rheumatoid arthritis and other inflammatoryRheumatoid arthritis and other inflammatory polyarthropathies
|
Musculoskeletal | 1.1 | 1.03 – 1.16 | 0.00212 | 1317 | 12039 | exclusion | phecode |
| 714.1 | Rheumatoid arthritis | Musculoskeletal | 1.14 | 1.06 – 1.21 | 0.000149 | 1048 | 9941 | exclusion | phecode |
| 714.2 | Juvenile rheumatoid arthritis | Musculoskeletal | 1.25 | 0.962 – 1.63 | 0.0948 | 60 | 605 | exclusion | phecode |
| 715 | Other inflammatory spondylopathies | Musculoskeletal | 1.09 | 1.01 – 1.18 | 0.0201 | 772 | 7646 | exclusion | phecode |
| 715.1 | Sacroiliitis NEC | Musculoskeletal | 1.12 | 0.957 – 1.3 | 0.162 | 185 | 1729 | exclusion | phecode |
| 715.2 | Ankylosing spondylitis | Musculoskeletal | 0.912 | 0.769 – 1.08 | 0.289 | 147 | 1449 | exclusion | phecode |
| 716 | Other arthropathies | Musculoskeletal | 1.06 | 1.04 – 1.09 | 7.21e-06 | 8387 | 21701 | exclusion | phecode |
| 716.1 | Unspecified polyarthropathy or polyarthritis | Musculoskeletal | 0.98 | 0.822 – 1.17 | 0.826 | 131 | 1274 | exclusion | phecode |
| 716.2 | Unspecified monoarthritis | Musculoskeletal | 0.814 | 0.647 – 1.02 | 0.0787 | 82 | 796 | exclusion | phecode |
| 716.9 | Arthropathy NOS | Musculoskeletal | 1.06 | 1.03 – 1.09 | 1.07e-05 | 8337 | 21692 | exclusion | phecode |
| 717 | Polymyalgia Rheumatica | Musculoskeletal | 0.999 | 0.828 – 1.21 | 0.991 | 123 | 1426 | exclusion | phecode |
| 720 | Spinal stenosis | Musculoskeletal | 1.09 | 1.05 – 1.14 | 6.82e-05 | 2394 | 18187 | exclusion | phecode |
| 720.1 | Spinal stenosis of lumbar region | Musculoskeletal | 1.05 | 0.999 – 1.11 | 0.0545 | 1709 | 14516 | exclusion | phecode |
| 721 | Spondylosis and allied disorders | Musculoskeletal | 1.08 | 1.04 – 1.12 | 0.000101 | 3468 | 21242 | exclusion | phecode |
| 721.1 | Spondylosis without myelopathy | Musculoskeletal | 1.07 | 1.03 – 1.11 | 0.000615 | 3226 | 20839 | exclusion | phecode |
| 721.2 | Spondylosis with myelopathy | Musculoskeletal | 1.09 | 0.997 – 1.19 | 0.0596 | 552 | 5358 | exclusion | phecode |
| 721.8 | Other allied disorders of spine | Musculoskeletal | 1.1 | 0.937 – 1.28 | 0.25 | 171 | 1668 | exclusion | phecode |
| 722 | Intervertebral disc disorders | Musculoskeletal | 1.1 | 1.07 – 1.14 | 1.55e-08 | 4091 | 22916 | exclusion | phecode |
| 722.1 | Displacement of intervertebral disc | Musculoskeletal | 1.07 | 1.03 – 1.12 | 0.0014 | 2401 | 20807 | exclusion | phecode |
| 722.3 | Schmorl's nodes | Musculoskeletal | 1.2 | 0.941 – 1.52 | 0.143 | 88 | 800 | exclusion | phecode |
| 722.6 | Degeneration of intervertebral disc | Musculoskeletal | 1.13 | 1.08 – 1.18 | 4.13e-08 | 2528 | 19956 | exclusion | phecode |
| 722.7 | Intervertebral disc disorder with myelopathy | Musculoskeletal | 1.04 | 0.929 – 1.17 | 0.479 | 331 | 3250 | exclusion | phecode |
| 722.8 | Postlaminectomy syndrome | Musculoskeletal | 1.13 | 0.99 – 1.28 | 0.0699 | 272 | 2556 | exclusion | phecode |
| 722.9 | Other and unspecified disc disorder | Musculoskeletal | 1.15 | 1.08 – 1.22 | 6.21e-06 | 1268 | 12605 | exclusion | phecode |
| 723 | Other disorders of cervical region | Musculoskeletal | 1.03 | 0.95 – 1.12 | 0.453 | 644 | 6240 | exclusion | phecode |
| 723.1 | Torticollis | Musculoskeletal | 0.994 | 0.848 – 1.17 | 0.938 | 176 | 1648 | exclusion | phecode |
| 724 | Other and unspecified disorders of back | Musculoskeletal | 1.06 | 1.01 – 1.1 | 0.00864 | 2753 | 21369 | exclusion | phecode |
| 724.1 | Disorders of sacrum | Musculoskeletal | 1.07 | 1.01 – 1.13 | 0.014 | 1528 | 14606 | exclusion | phecode |
| 724.2 | Disorders of coccyx | Musculoskeletal | 0.967 | 0.857 – 1.09 | 0.583 | 297 | 2922 | exclusion | phecode |
| 724.8 | Other symptoms referable to back | Musculoskeletal | 1.12 | 1.03 – 1.22 | 0.00967 | 639 | 6253 | exclusion | phecode |
| 724.9 | Other unspecified back disorders | Musculoskeletal | 1.06 | 0.989 – 1.14 | 0.0967 | 907 | 9016 | exclusion | phecode |
| 726 | Peripheral enthesopathies and allied syndromes | Musculoskeletal | 0.986 | 0.959 – 1.02 | 0.349 | 6742 | 20259 | exclusion | phecode |
| 726.1 | Enthesopathy | Musculoskeletal | 0.984 | 0.953 – 1.02 | 0.319 | 5086 | 20199 | exclusion | phecode |
| 726.2 | Synoviopathy | Musculoskeletal | 0.963 | 0.888 – 1.04 | 0.359 | 678 | 6452 | exclusion | phecode |
| 726.3 | Bursitis | Musculoskeletal | 0.97 | 0.914 – 1.03 | 0.324 | 1257 | 10809 | exclusion | phecode |
| 726.4 | Calcaneal spur; Exostosis NOS | Musculoskeletal | 0.952 | 0.885 – 1.03 | 0.193 | 827 | 7503 | exclusion | phecode |
| 727 | Other disorders of synovium, tendon, and bursa | Musculoskeletal | 1.01 | 0.976 – 1.04 | 0.629 | 5022 | 20198 | exclusion | phecode |
| 727.1 | Synovitis and tenosynovitis | Musculoskeletal | 1.01 | 0.965 – 1.06 | 0.653 | 2123 | 16637 | exclusion | phecode |
| 727.2 | Bursitis disorders | Musculoskeletal | 1.09 | 0.962 – 1.24 | 0.173 | 270 | 2571 | exclusion | phecode |
| 727.4 | Ganglion and cyst of synovium, tendon, and bursa | Musculoskeletal | 0.952 | 0.889 – 1.02 | 0.155 | 952 | 8952 | exclusion | phecode |
| 727.5 | Rupture of synovium | Musculoskeletal | 0.993 | 0.881 – 1.12 | 0.911 | 307 | 2936 | exclusion | phecode |
| 727.6 | Rupture of tendon, nontraumatic | Musculoskeletal | 1.02 | 0.968 – 1.08 | 0.449 | 1575 | 13658 | exclusion | phecode |
| 727.7 | Contracture of tendon (sheath) | Musculoskeletal | 1.09 | 0.984 – 1.21 | 0.101 | 417 | 4097 | exclusion | phecode |
| 727.8 | Plica syndrome | Musculoskeletal | 1.17 | 0.958 – 1.44 | 0.122 | 108 | 967 | exclusion | phecode |
| 728 | Disorders of muscle, ligament, and fascia | Musculoskeletal | 1.04 | 0.997 – 1.08 | 0.0715 | 2948 | 19613 | exclusion | phecode |
| 728.1 | Muscular calcification and ossification | Musculoskeletal | 1.22 | 0.94 – 1.59 | 0.135 | 59 | 544 | exclusion | phecode |
| 728.2 | Laxity of ligament or hypermobility syndrome | Musculoskeletal | 0.999 | 0.856 – 1.16 | 0.985 | 183 | 1939 | exclusion | phecode |
| 728.7 | Fasciitis | Musculoskeletal | 0.949 | 0.904 – 0.997 | 0.0361 | 1908 | 15236 | exclusion | phecode |
| 728.71 |
Contracture of palmar fascia [Dupuytren'sContracture of palmar fascia [Dupuytren's disease]
|
Musculoskeletal | 0.965 | 0.848 – 1.1 | 0.59 | 253 | 2407 | exclusion | phecode |
| 729 | Other disorders of soft tissues | Musculoskeletal | 1.02 | 0.973 – 1.06 | 0.463 | 2318 | 17908 | exclusion | phecode |
| 729.1 | Rheumatism, unspecified and fibrositis | Musculoskeletal | 0.867 | 0.62 – 1.21 | 0.405 | 40 | 481 | exclusion | phecode |
| 729.3 | Panniculitis | Musculoskeletal | 1.11 | 0.874 – 1.4 | 0.4 | 79 | 742 | exclusion | phecode |
| 729.7 | Nontraumatic compartment syndrome | Musculoskeletal | 1.04 | 0.74 – 1.45 | 0.834 | 38 | 434 | exclusion | phecode |
| 731 |
Osteitis deformans and osteopathies associatedOsteitis deformans and osteopathies associated with other disorders classified elsewhere
|
Musculoskeletal | 1.21 | 1.01 – 1.46 | 0.0405 | 133 | 1251 | exclusion | phecode |
| 732 | Osteochondropathies | Musculoskeletal | 0.988 | 0.87 – 1.12 | 0.847 | 286 | 2718 | exclusion | phecode |
| 732.1 | Juvenile osteochondrosis | Musculoskeletal | 1.07 | 0.909 – 1.27 | 0.403 | 153 | 1429 | exclusion | phecode |
| 732.7 | Osteochondritis dissecans | Musculoskeletal | 0.852 | 0.664 – 1.09 | 0.208 | 70 | 668 | exclusion | phecode |
| 733 | Other disorders of bone and cartilage | Musculoskeletal | 0.945 | 0.908 – 0.984 | 0.00661 | 3013 | 17761 | exclusion | phecode |
| 733.2 | Cyst of bone | Musculoskeletal | 0.917 | 0.768 – 1.1 | 0.341 | 138 | 1312 | exclusion | phecode |
| 733.4 | Aseptic necrosis of bone | Musculoskeletal | 1.07 | 0.953 – 1.2 | 0.26 | 338 | 3340 | exclusion | phecode |
| 733.6 | Costochondritis | Musculoskeletal | 1.05 | 0.923 – 1.2 | 0.448 | 259 | 2494 | exclusion | phecode |
| 733.8 | Malunion and nonunion of fracture | Musculoskeletal | 1 | 0.917 – 1.09 | 0.989 | 581 | 5684 | exclusion | phecode |
| 733.9 | Chondromalacia | Musculoskeletal | 1.19 | 0.937 – 1.5 | 0.156 | 80 | 736 | exclusion | phecode |
| 735 | Acquired foot deformities | Musculoskeletal | 1.02 | 0.977 – 1.07 | 0.355 | 2306 | 19283 | exclusion | phecode |
| 735.1 | Flat foot | Musculoskeletal | 1 | 0.907 – 1.11 | 0.945 | 435 | 4023 | exclusion | phecode |
| 735.2 | Acquired toe deformities | Musculoskeletal | 1.04 | 0.965 – 1.12 | 0.312 | 856 | 7523 | exclusion | phecode |
| 735.21 | Hammer toe (acquired) | Musculoskeletal | 1.11 | 1.01 – 1.22 | 0.0236 | 529 | 4656 | exclusion | phecode |
| 735.23 | Hallux rigidus | Musculoskeletal | 0.937 | 0.821 – 1.07 | 0.332 | 259 | 2526 | exclusion | phecode |
| 735.3 | Hallux valgus (Bunion) | Musculoskeletal | 0.99 | 0.926 – 1.06 | 0.77 | 1015 | 9380 | exclusion | phecode |
| 736 | Other acquired deformities of limbs | Musculoskeletal | 1.02 | 0.969 – 1.07 | 0.487 | 1900 | 17398 | exclusion | phecode |
| 736.1 | Acquired deformities of forearm | Musculoskeletal | 1.16 | 0.901 – 1.48 | 0.253 | 69 | 654 | exclusion | phecode |
| 736.2 | Acquired deformities of finger | Musculoskeletal | 0.939 | 0.793 – 1.11 | 0.461 | 160 | 1446 | exclusion | phecode |
| 736.3 | Acquired deformities of hip | Musculoskeletal | 1.03 | 0.756 – 1.39 | 0.869 | 45 | 435 | exclusion | phecode |
| 736.4 | Genu valgum or varum (acquired) | Musculoskeletal | 0.965 | 0.832 – 1.12 | 0.631 | 209 | 1991 | exclusion | phecode |
| 736.5 | Acquired deformities of knee | Musculoskeletal | 0.914 | 0.771 – 1.08 | 0.298 | 159 | 1534 | exclusion | phecode |
| 736.6 | Unequal leg length (acquired) | Musculoskeletal | 1.03 | 0.901 – 1.18 | 0.667 | 234 | 2251 | exclusion | phecode |
| 737 | Curvature of spine | Musculoskeletal | 0.99 | 0.928 – 1.06 | 0.752 | 1069 | 10298 | exclusion | phecode |
| 737.1 | Kyphosis (acquired) | Musculoskeletal | 0.987 | 0.877 – 1.11 | 0.827 | 320 | 3074 | exclusion | phecode |
| 737.2 | Lordosis (acquired) | Musculoskeletal | 1.26 | 0.929 – 1.7 | 0.137 | 49 | 455 | exclusion | phecode |
| 737.3 | Kyphoscoliosis and scoliosis | Musculoskeletal | 1.01 | 0.936 – 1.08 | 0.838 | 825 | 7980 | exclusion | phecode |
| 738 | Other acquired musculoskeletal deformity | Musculoskeletal | 1.05 | 0.992 – 1.1 | 0.096 | 1616 | 15951 | exclusion | phecode |
| 738.4 | Acquired spondylolisthesis | Musculoskeletal | 1.08 | 0.992 – 1.17 | 0.0772 | 645 | 6521 | exclusion | phecode |
| 739 | Contracture of joint | Musculoskeletal | 0.945 | 0.854 – 1.05 | 0.272 | 430 | 4163 | exclusion | phecode |
| 740 | Osteoarthrosis | Musculoskeletal | 1.06 | 1.03 – 1.09 | 1.5e-05 | 10047 | 21168 | exclusion | phecode |
| 740.1 | Osteoarthritis; localized | Musculoskeletal | 1.03 | 0.999 – 1.07 | 0.059 | 4429 | 18620 | exclusion | phecode |
| 740.11 | Osteoarthrosis, localized, primary | Musculoskeletal | 1.03 | 0.992 – 1.07 | 0.123 | 3893 | 17585 | exclusion | phecode |
| 740.12 | Osteoarthrosis, localized, secondary | Musculoskeletal | 1.03 | 0.937 – 1.13 | 0.549 | 513 | 4599 | exclusion | phecode |
| 740.2 | Osteoarthrosis, generalized | Musculoskeletal | 1.02 | 0.951 – 1.09 | 0.579 | 945 | 7466 | exclusion | phecode |
| 740.3 |
Osteoarthrosis involving more than one siteOsteoarthrosis involving more than one site, but not specified as generalized
|
Musculoskeletal | 1.03 | 0.891 – 1.19 | 0.691 | 220 | 2250 | exclusion | phecode |
| 740.9 | Osteoarthrosis NOS | Musculoskeletal | 1.06 | 1.03 – 1.09 | 1.61e-05 | 9594 | 21047 | exclusion | phecode |
| 741 | Symptoms and disorders of the joints | Musculoskeletal | 1.02 | 0.986 – 1.05 | 0.313 | 5754 | 24053 | exclusion | phecode |
| 741.1 | Ankylosis of joint | Musculoskeletal | 1.1 | 0.938 – 1.29 | 0.241 | 175 | 1696 | exclusion | phecode |
| 741.2 | Stiffness of joint | Musculoskeletal | 0.945 | 0.879 – 1.02 | 0.127 | 862 | 8270 | exclusion | phecode |
| 741.3 | Difficulty in walking | Musculoskeletal | 1.06 | 1 – 1.12 | 0.0379 | 1594 | 14373 | exclusion | phecode |
| 741.4 | Joint effusions | Musculoskeletal | 1.04 | 0.988 – 1.09 | 0.132 | 1735 | 16175 | exclusion | phecode |
| 741.5 | Hemarthrosis | Musculoskeletal | 0.916 | 0.692 – 1.21 | 0.539 | 57 | 632 | exclusion | phecode |
| 741.6 | Villonodular synovitis | Musculoskeletal | 1 | 0.744 – 1.35 | 0.998 | 47 | 483 | exclusion | phecode |
| 742 | Derangement of joint, non-traumatic | Musculoskeletal | 1.06 | 1.02 – 1.1 | 0.00202 | 3133 | 22952 | exclusion | phecode |
| 742.1 | Loose body in joint | Musculoskeletal | 1.2 | 0.987 – 1.45 | 0.0676 | 117 | 1120 | exclusion | phecode |
| 742.2 |
Pathological, developmental or recurrentPathological, developmental or recurrent dislocation
|
Musculoskeletal | 1.05 | 0.914 – 1.21 | 0.473 | 218 | 2200 | exclusion | phecode |
| 742.8 | Articular cartilage disorder | Musculoskeletal | 1.04 | 0.892 – 1.22 | 0.594 | 183 | 1776 | exclusion | phecode |
| 742.9 | Other derangement of joint | Musculoskeletal | 1.06 | 1.02 – 1.1 | 0.00368 | 2922 | 22497 | exclusion | phecode |
| 743 |
Osteoporosis, osteopenia and pathologicalOsteoporosis, osteopenia and pathological fracture
|
Musculoskeletal | 0.986 | 0.956 – 1.02 | 0.349 | 5921 | 25033 | exclusion | phecode |
| 743.1 | Osteoporosis | Musculoskeletal | 0.98 | 0.934 – 1.03 | 0.398 | 2287 | 12318 | exclusion | phecode |
| 743.11 | Osteoporosis NOS | Musculoskeletal | 0.984 | 0.938 – 1.03 | 0.505 | 2254 | 12203 | exclusion | phecode |
| 743.12 | Senile osteoporosis | Musculoskeletal | 0.946 | 0.852 – 1.05 | 0.307 | 420 | 3516 | exclusion | phecode |
| 743.13 | Other specified osteoporosis | Musculoskeletal | 0.949 | 0.819 – 1.1 | 0.482 | 220 | 1990 | exclusion | phecode |
| 743.2 | Pathologic fracture | Musculoskeletal | 0.935 | 0.863 – 1.01 | 0.101 | 701 | 6625 | exclusion | phecode |
| 743.21 | Pathologic fracture of vertebrae | Musculoskeletal | 0.942 | 0.832 – 1.07 | 0.35 | 282 | 2821 | exclusion | phecode |
| 743.22 | Pathologic fracture of femur | Musculoskeletal | 0.96 | 0.772 – 1.19 | 0.712 | 98 | 853 | exclusion | phecode |
| 743.4 | Stress fracture | Musculoskeletal | 0.956 | 0.844 – 1.08 | 0.484 | 293 | 2810 | exclusion | phecode |
| 743.9 |
Osteopenia or other disorder of bone andOsteopenia or other disorder of bone and cartilage
|
Musculoskeletal | 0.982 | 0.95 – 1.02 | 0.297 | 4481 | 23657 | exclusion | phecode |
| 745 | Pain in joint | Musculoskeletal | 0.994 | 0.972 – 1.02 | 0.62 | 13731 | 17790 | exclusion | phecode |
| 747 | Cardiac and circulatory congenital anomalies | Congenital Anomalies | 1.03 | 0.972 – 1.09 | 0.337 | 1398 | 14480 | exclusion | phecode |
| 747.1 | Cardiac congenital anomalies | Congenital Anomalies | 1.02 | 0.953 – 1.08 | 0.624 | 1082 | 11354 | exclusion | phecode |
| 747.11 | Cardiac shunt/ heart septal defect | Congenital Anomalies | 1.02 | 0.914 – 1.13 | 0.78 | 405 | 4365 | exclusion | phecode |
| 747.12 | Valvular heart disease/ heart chambers | Congenital Anomalies | 1.02 | 0.923 – 1.13 | 0.684 | 428 | 4577 | exclusion | phecode |
| 747.13 | Congenital anomalies of great vessels | Congenital Anomalies | 0.984 | 0.865 – 1.12 | 0.81 | 253 | 2575 | exclusion | phecode |
| 747.2 |
Congenital anomalies of peripheral vascularCongenital anomalies of peripheral vascular system
|
Congenital Anomalies | 0.992 | 0.885 – 1.11 | 0.896 | 342 | 3381 | exclusion | phecode |
| 748 | Anomalies of respiratory system, congenital | Congenital Anomalies | 1.06 | 0.82 – 1.36 | 0.67 | 70 | 762 | exclusion | phecode |
| 749 | Congenital anomalies of face and neck | Congenital Anomalies | 0.953 | 0.859 – 1.06 | 0.363 | 411 | 4051 | exclusion | phecode |
| 749.1 | Cleft palate | Congenital Anomalies | 0.869 | 0.692 – 1.09 | 0.228 | 82 | 745 | exclusion | phecode |
| 749.2 | Congenital anomalies of skull and face bones | Congenital Anomalies | 0.935 | 0.746 – 1.17 | 0.56 | 82 | 801 | exclusion | phecode |
| 750 | Digestive congenital anomalies | Congenital Anomalies | 1.04 | 0.951 – 1.13 | 0.422 | 605 | 5950 | exclusion | phecode |
| 750.1 | Upper gastrointestinal congenital anomalies | Congenital Anomalies | 1.09 | 0.957 – 1.25 | 0.189 | 246 | 2357 | exclusion | phecode |
| 750.11 | Esophageal atresia/tracheoesophageal fistula | Congenital Anomalies | 0.909 | 0.71 – 1.17 | 0.453 | 73 | 735 | exclusion | phecode |
| 750.13 | Congenital anomalies of mouth/tongue | Congenital Anomalies | 0.983 | 0.778 – 1.24 | 0.883 | 81 | 708 | exclusion | phecode |
| 750.14 | Congenital anomalies of esophagus | Congenital Anomalies | 0.971 | 0.764 – 1.24 | 0.812 | 80 | 838 | exclusion | phecode |
| 750.15 | Congenital anomalies of stomach | Congenital Anomalies | 1.5 | 1.07 – 2.11 | 0.0201 | 37 | 368 | exclusion | phecode |
| 750.2 | Lower gastrointestinal congenital anomalies | Congenital Anomalies | 1.04 | 0.927 – 1.16 | 0.531 | 361 | 3584 | exclusion | phecode |
| 750.21 | Congenital anomalies of intestine | Congenital Anomalies | 1.05 | 0.908 – 1.21 | 0.528 | 215 | 2105 | exclusion | phecode |
| 750.22 |
Congenital anomaly of gallbladder, bile ductsCongenital anomaly of gallbladder, bile ducts, liver, pancreas
|
Congenital Anomalies | 1.05 | 0.891 – 1.24 | 0.546 | 149 | 1500 | exclusion | phecode |
| 751 | Genitourinary congenital anomalies | Congenital Anomalies | 0.978 | 0.923 – 1.04 | 0.448 | 1334 | 13440 | exclusion | phecode |
| 751.1 | Congenital anomalies of genital organs | Congenital Anomalies | 0.982 | 0.886 – 1.09 | 0.735 | 410 | 4196 | exclusion | phecode |
| 751.11 | Congenital anomalies of female genital organs | Congenital Anomalies | 1.01 | 0.892 – 1.14 | 0.872 | 291 | 2875 | exclusion | phecode |
| 751.12 | Congenital anomalies of male genital organs | Congenital Anomalies | 0.94 | 0.756 – 1.17 | 0.577 | 91 | 1067 | exclusion | phecode |
| 751.2 | Congenital anomalies of urinary system | Congenital Anomalies | 0.965 | 0.899 – 1.04 | 0.318 | 881 | 8798 | exclusion | phecode |
| 751.21 | Cystic kidney disease | Congenital Anomalies | 0.933 | 0.858 – 1.02 | 0.109 | 614 | 6130 | exclusion | phecode |
| 751.22 | Other specified congenital anomalies of kidney | Congenital Anomalies | 1.03 | 0.889 – 1.2 | 0.675 | 189 | 1953 | exclusion | phecode |
| 751.3 | Obstructive genitourinary defect | Congenital Anomalies | 1.15 | 0.961 – 1.38 | 0.127 | 138 | 1312 | exclusion | phecode |
| 752 | Nervous system congenital anomalies | Congenital Anomalies | 1.04 | 0.965 – 1.13 | 0.286 | 732 | 7453 | exclusion | phecode |
| 752.1 | Neural tube defects | Congenital Anomalies | 1.02 | 0.936 – 1.11 | 0.637 | 583 | 5983 | exclusion | phecode |
| 752.11 | Spina bifida | Congenital Anomalies | 0.906 | 0.755 – 1.09 | 0.289 | 136 | 1298 | exclusion | phecode |
| 752.2 |
Other specified congenital anomalies of nervousOther specified congenital anomalies of nervous system
|
Congenital Anomalies | 1.04 | 0.888 – 1.23 | 0.607 | 170 | 1656 | exclusion | phecode |
| 753 | Congenital anomalies of the eye | Congenital Anomalies | 0.852 | 0.715 – 1.02 | 0.0741 | 140 | 1380 | exclusion | phecode |
| 753.1 | Congenital cataract and lens anomalies | Congenital Anomalies | 0.874 | 0.635 – 1.2 | 0.411 | 39 | 406 | exclusion | phecode |
| 753.2 | Congenital anomalies of posterior segment of eye | Congenital Anomalies | 0.754 | 0.548 – 1.04 | 0.0835 | 41 | 382 | exclusion | phecode |
| 754 | Congenital musculoskeletal deformities of spine | Congenital Anomalies | 1.09 | 1.01 – 1.18 | 0.0243 | 758 | 7702 | exclusion | phecode |
| 754.1 | Lumbosacral spondylolysis, congenital | Congenital Anomalies | 1.07 | 0.854 – 1.33 | 0.572 | 86 | 876 | exclusion | phecode |
| 754.2 | Spondylolisthesis, congenital | Congenital Anomalies | 1.07 | 0.953 – 1.19 | 0.266 | 343 | 3512 | exclusion | phecode |
| 755 | Congenital anomalies of limbs | Congenital Anomalies | 0.977 | 0.894 – 1.07 | 0.61 | 566 | 5372 | exclusion | phecode |
| 755.1 | Congenital deformities of feet | Congenital Anomalies | 0.894 | 0.785 – 1.02 | 0.0877 | 262 | 2561 | exclusion | phecode |
| 755.4 |
Congenital anomalies of upper limb, includingCongenital anomalies of upper limb, including shoulder girdle
|
Congenital Anomalies | 1.39 | 1.03 – 1.86 | 0.0287 | 55 | 526 | exclusion | phecode |
| 755.6 |
Other congenital anomalies of lower limbOther congenital anomalies of lower limb, including pelvic girdle
|
Congenital Anomalies | 1.01 | 0.888 – 1.15 | 0.868 | 262 | 2458 | exclusion | phecode |
| 755.61 | Congenital hip dysplasia and deformity | Congenital Anomalies | 0.98 | 0.826 – 1.16 | 0.814 | 156 | 1432 | exclusion | phecode |
| 756 | Other congenital musculoskeletal anomalies | Congenital Anomalies | 1.05 | 0.976 – 1.12 | 0.209 | 972 | 9387 | exclusion | phecode |
| 756.1 | Congenital anomalies of abdominal wall; diaphram | Congenital Anomalies | 0.924 | 0.68 – 1.25 | 0.61 | 50 | 495 | exclusion | phecode |
| 756.2 |
Pectus and other congenital anomalies ofPectus and other congenital anomalies of ribs/sternum
|
Congenital Anomalies | 0.757 | 0.569 – 1.01 | 0.0558 | 58 | 560 | exclusion | phecode |
| 756.3 |
Congenital anomalies of muscle, tendon, fasciaCongenital anomalies of muscle, tendon, fascia, and connective tissue
|
Congenital Anomalies | 0.921 | 0.802 – 1.06 | 0.243 | 233 | 2288 | exclusion | phecode |
| 756.5 | Congenital osteodystrophies | Congenital Anomalies | 1.09 | 1 – 1.18 | 0.0394 | 697 | 6684 | exclusion | phecode |
| 757 | Congenital anomalies of the integument | Congenital Anomalies | 0.967 | 0.85 – 1.1 | 0.61 | 271 | 2536 | exclusion | phecode |
| 758 | Chromosomal anomalies and genetic disorders | Congenital Anomalies | 1.01 | 0.844 – 1.21 | 0.894 | 137 | 1336 | exclusion | phecode |
| 758.1 | Chromosomal anomalies | Congenital Anomalies | 0.999 | 0.807 – 1.24 | 0.994 | 98 | 992 | exclusion | phecode |
| 759 | Other and unspecified congenital anomalies | Congenital Anomalies | 1.05 | 0.949 – 1.16 | 0.346 | 424 | 3973 | exclusion | phecode |
| 759.1 | Anomalies of endocrine glands, congenital | Congenital Anomalies | 1.06 | 0.803 – 1.4 | 0.678 | 56 | 513 | exclusion | phecode |
| 760 | Back pain | Symptoms | 1.08 | 1.05 – 1.11 | 3.34e-10 | 10738 | 20772 | exclusion | phecode |
| 761 | Cervicalgia | Symptoms | 1.07 | 1.03 – 1.1 | 0.000101 | 4421 | 26663 | exclusion | phecode |
| 763 |
Thoracic or lumbosacral neuritis orThoracic or lumbosacral neuritis or radiculitis, unspecified
|
Symptoms | 1.08 | 1.04 – 1.13 | 0.000277 | 2374 | 21166 | exclusion | phecode |
| 764 | Sciatica | Symptoms | 1.07 | 1.03 – 1.12 | 0.00198 | 2289 | 20904 | exclusion | phecode |
| 765 | Cervical radiculitis | Symptoms | 1.11 | 1.05 – 1.18 | 0.000495 | 1207 | 11704 | exclusion | phecode |
| 766 | Neuralgia, neuritis, and radiculitis NOS | Symptoms | 1.09 | 1.05 – 1.13 | 4.05e-06 | 3417 | 24701 | exclusion | phecode |
| 767 | Cervicocranial/Cervicobrachial syndrome | Symptoms | 1.02 | 0.805 – 1.3 | 0.855 | 74 | 757 | exclusion | phecode |
| 769 | Nonallopathic lesions NEC | Symptoms | 1 | 0.929 – 1.08 | 0.956 | 765 | 7539 | exclusion | phecode |
| 770 | Myalgia and myositis unspecified | Symptoms | 1.06 | 1.03 – 1.1 | 0.000526 | 3803 | 23094 | exclusion | phecode |
| 771 | Musculoskeletal symptoms referable to limbs | Symptoms | 1.03 | 0.989 – 1.07 | 0.159 | 3156 | 23849 | exclusion | phecode |
| 771.1 | Swelling of limb | Symptoms | 1.04 | 1 – 1.08 | 0.0387 | 3650 | 23809 | exclusion | phecode |
| 771.2 | Cramp of limb | Symptoms | 1.02 | 0.939 – 1.1 | 0.681 | 704 | 6697 | exclusion | phecode |
| 772 | Symptoms of the muscles | Symptoms | 0.995 | 0.941 – 1.05 | 0.856 | 1406 | 13290 | exclusion | phecode |
| 772.1 | Muscular wasting and disuse atrophy | Symptoms | 1.14 | 1.01 – 1.29 | 0.0329 | 293 | 2927 | exclusion | phecode |
| 772.2 | Spasm of muscle | Symptoms | 1.04 | 0.989 – 1.1 | 0.123 | 1579 | 15578 | exclusion | phecode |
| 772.3 | Muscle weakness | Symptoms | 1.07 | 1.02 – 1.13 | 0.00439 | 1854 | 17810 | exclusion | phecode |
| 772.4 | Rhabdomyolysis | Symptoms | 1.25 | 1.02 – 1.53 | 0.0299 | 110 | 1018 | exclusion | phecode |
| 772.6 | Facial weakness | Symptoms | 1.01 | 0.899 – 1.13 | 0.869 | 321 | 2911 | exclusion | phecode |
| 780 | Hypothermia/Chills | Symptoms | 0.972 | 0.862 – 1.1 | 0.648 | 308 | 2928 | exclusion | phecode |
| 781 |
Symptoms involving nervous and musculoskeletalSymptoms involving nervous and musculoskeletal systems
|
Symptoms | 1.07 | 1.01 – 1.12 | 0.0115 | 1770 | 16608 | exclusion | phecode |
| 781.1 | Loss of height | Symptoms | 0.87 | 0.689 – 1.1 | 0.245 | 81 | 715 | exclusion | phecode |
| 781.2 | Abnormal posture | Symptoms | 1.19 | 0.842 – 1.68 | 0.325 | 38 | 361 | exclusion | phecode |
| 782.3 | Edema | Symptoms | 1.06 | 1.02 – 1.1 | 0.00145 | 3727 | 24301 | exclusion | phecode |
| 782.6 | Pallor and flushing | Symptoms | 0.979 | 0.901 – 1.06 | 0.62 | 647 | 6380 | exclusion | phecode |
| 783 | Fever of unknown origin | Symptoms | 1.02 | 0.986 – 1.06 | 0.252 | 3739 | 27528 | exclusion | phecode |
| 783.1 | Postprocedural fever | Symptoms | 1.13 | 0.975 – 1.32 | 0.103 | 181 | 1996 | exclusion | phecode |
| 785 | Abdominal pain | Symptoms | 1.05 | 1.03 – 1.08 | 3.96e-05 | 11179 | 20334 | exclusion | phecode |
| 788 | Syncope and collapse | Symptoms | 1.02 | 0.975 – 1.06 | 0.439 | 2530 | 23532 | exclusion | phecode |
| 789 | Nausea and vomiting | Symptoms | 1.04 | 1.01 – 1.06 | 0.0124 | 7227 | 24228 | exclusion | phecode |
| 789.1 | Persistent vomiting | Symptoms | 1.11 | 1.01 – 1.22 | 0.026 | 557 | 5526 | exclusion | phecode |
| 790 | Nonspecific findings on examination of blood | Symptoms | 0.996 | 0.942 – 1.05 | 0.872 | 1491 | 14289 | exclusion | phecode |
| 790.1 | Elevated sedimentation rate | Symptoms | 1.1 | 0.919 – 1.31 | 0.305 | 146 | 1549 | exclusion | phecode |
| 790.6 | Other abnormal blood chemistry | Symptoms | 1 | 0.971 – 1.04 | 0.863 | 4841 | 25573 | exclusion | phecode |
| 790.8 | Elevated C-reactive protein (CRP) | Symptoms | 1.17 | 1.01 – 1.34 | 0.0363 | 211 | 2147 | exclusion | phecode |
| 790.9 | Abnormal arterial blood gases | Symptoms | 1.06 | 0.856 – 1.32 | 0.587 | 91 | 960 | exclusion | phecode |
| 791 | Gangrene | Symptoms | 1.27 | 1.09 – 1.48 | 0.00241 | 185 | 1886 | exclusion | phecode |
| 792 |
Abnormal Papanicolaou smear of cervix andAbnormal Papanicolaou smear of cervix and cervical HPV
|
Genitourinary | 1.01 | 0.965 – 1.06 | 0.596 | 2070 | 10699 | exclusion | phecode |
| 792.1 |
Papanicolaou smear of cervix or vagina withPapanicolaou smear of cervix or vagina with atypical squamous cells
|
Genitourinary | 1.04 | 0.965 – 1.12 | 0.315 | 861 | 7390 | exclusion | phecode |
| 794 |
Abnormal results of other function studiesAbnormal results of other function studies (bladder, pancreas, placenta, spleen, etc)
|
Symptoms | 0.971 | 0.865 – 1.09 | 0.619 | 328 | 3279 | exclusion | phecode |
| 795 |
Other and nonspecific abnormal cytologicalOther and nonspecific abnormal cytological, histological and immunological findings
|
Symptoms | 1.02 | 0.963 – 1.07 | 0.543 | 1523 | 14275 | exclusion | phecode |
| 795.8 | Abnormal tumor markers | Symptoms | 0.978 | 0.916 – 1.04 | 0.509 | 1035 | 8782 | exclusion | phecode |
| 795.81 | Elevated carcinoembryonic antigen [CEA] | Symptoms | 1.02 | 0.736 – 1.41 | 0.904 | 41 | 378 | exclusion | phecode |
| 795.82 | Elevated cancer antigen 125 [CA 125] | Symptoms | 0.989 | 0.821 – 1.19 | 0.91 | 121 | 1295 | exclusion | phecode |
| 796 | Elevated prostate specific antigen [PSA] | Genitourinary | 0.932 | 0.873 – 0.994 | 0.0319 | 1222 | 5805 | exclusion | phecode |
| 797 | Shock | Symptoms | 1.07 | 0.955 – 1.19 | 0.252 | 357 | 3700 | exclusion | phecode |
| 797.1 | Cardiogenic shock | Symptoms | 1.09 | 0.906 – 1.31 | 0.365 | 128 | 1445 | exclusion | phecode |
| 798 | Malaise and fatigue | Symptoms | 1.03 | 1 – 1.06 | 0.0478 | 7605 | 23888 | exclusion | phecode |
| 798.1 | Chronic fatigue syndrome | Symptoms | 1.03 | 0.97 – 1.09 | 0.34 | 1228 | 11815 | exclusion | phecode |
| 800 | Fracture of lower limb | Injuries & Poisonings | 1.03 | 0.975 – 1.08 | 0.315 | 1612 | 15472 | exclusion | phecode |
| 800.1 | Fracture of neck of femur | Injuries & Poisonings | 1.06 | 0.943 – 1.19 | 0.335 | 331 | 3087 | exclusion | phecode |
| 800.2 | Fracture of unspecified part of femur | Injuries & Poisonings | 1.05 | 0.949 – 1.16 | 0.347 | 447 | 4222 | exclusion | phecode |
| 800.3 | Fracture of tibia and fibula | Injuries & Poisonings | 0.97 | 0.893 – 1.05 | 0.469 | 649 | 6185 | exclusion | phecode |
| 800.4 | Fracture of patella | Injuries & Poisonings | 1.05 | 0.921 – 1.2 | 0.452 | 245 | 2356 | exclusion | phecode |
| 801 | Fracture of ankle and foot | Injuries & Poisonings | 1.01 | 0.959 – 1.06 | 0.703 | 1657 | 15592 | exclusion | phecode |
| 801.1 | Fracture of foot | Injuries & Poisonings | 1.01 | 0.939 – 1.09 | 0.741 | 802 | 7747 | exclusion | phecode |
| 802 | Fracture of pelvis | Injuries & Poisonings | 1 | 0.876 – 1.14 | 0.996 | 256 | 2434 | exclusion | phecode |
| 803 | Fracture of upper limb | Injuries & Poisonings | 0.967 | 0.915 – 1.02 | 0.239 | 1450 | 13944 | exclusion | phecode |
| 803.1 | Fracture of humerus | Injuries & Poisonings | 0.994 | 0.906 – 1.09 | 0.896 | 517 | 4840 | exclusion | phecode |
| 803.2 | Fracture of radius and ulna | Injuries & Poisonings | 0.959 | 0.89 – 1.03 | 0.269 | 786 | 7680 | exclusion | phecode |
| 803.21 | Colles' fracture | Injuries & Poisonings | 1.05 | 0.906 – 1.23 | 0.496 | 203 | 1919 | exclusion | phecode |
| 803.3 | Fracture of clavicle or scapula | Injuries & Poisonings | 0.962 | 0.862 – 1.07 | 0.484 | 371 | 3505 | exclusion | phecode |
| 804 | Fracture of hand or wrist | Injuries & Poisonings | 0.973 | 0.915 – 1.04 | 0.392 | 1185 | 11213 | exclusion | phecode |
| 805 |
Fracture of vertebral column without mention ofFracture of vertebral column without mention of spinal cord injury
|
Injuries & Poisonings | 1.07 | 0.992 – 1.15 | 0.083 | 846 | 8373 | exclusion | phecode |
| 807 | Fracture of ribs | Injuries & Poisonings | 0.933 | 0.845 – 1.03 | 0.171 | 451 | 4280 | exclusion | phecode |
| 809 | Fracture of unspecified bones | Injuries & Poisonings | 0.987 | 0.942 – 1.03 | 0.578 | 2093 | 19345 | exclusion | phecode |
| 816 | Cerebral laceration and contusion | Injuries & Poisonings | 1.59 | 1.11 – 2.28 | 0.0115 | 40 | 375 | exclusion | phecode |
| 817 | Concussion | Injuries & Poisonings | 1.04 | 0.96 – 1.12 | 0.357 | 756 | 7317 | exclusion | phecode |
| 818 | Intracranial hemorrhage (injury) | Injuries & Poisonings | 1.09 | 0.945 – 1.26 | 0.231 | 205 | 1902 | exclusion | phecode |
| 818.1 | Subdural hemorrhage (injury) | Injuries & Poisonings | 1.25 | 0.954 – 1.63 | 0.107 | 56 | 529 | exclusion | phecode |
| 818.2 | Subarachnoid hemorrhage (injury) | Injuries & Poisonings | 1.2 | 0.941 – 1.53 | 0.14 | 67 | 641 | exclusion | phecode |
| 819 |
Skull and face fracture and other intercranialSkull and face fracture and other intercranial injury
|
Injuries & Poisonings | 1.04 | 0.991 – 1.1 | 0.105 | 1636 | 15813 | exclusion | phecode |
| 830 | Dislocation | Injuries & Poisonings | 0.962 | 0.923 – 1 | 0.0572 | 2785 | 23598 | exclusion | phecode |
| 835 | Internal derangement of knee | Injuries & Poisonings | 0.968 | 0.918 – 1.02 | 0.219 | 1618 | 15042 | exclusion | phecode |
| 836 | Traumatic arthropathy | Injuries & Poisonings | 0.911 | 0.81 – 1.02 | 0.119 | 317 | 3109 | exclusion | phecode |
| 840 | Sprains and strains | Injuries & Poisonings | 0.998 | 0.969 – 1.03 | 0.898 | 5631 | 25237 | exclusion | phecode |
| 840.1 | Muscle/tendon sprain | Injuries & Poisonings | 1.01 | 0.9 – 1.14 | 0.856 | 340 | 3303 | exclusion | phecode |
| 840.2 | Rotator cuff (capsule) sprain | Injuries & Poisonings | 1.03 | 0.968 – 1.1 | 0.319 | 1033 | 10071 | exclusion | phecode |
| 840.3 | Joint/ligament sprain | Injuries & Poisonings | 0.987 | 0.943 – 1.03 | 0.578 | 2200 | 17605 | exclusion | phecode |
| 841 | Sprains and strains of back and neck | Injuries & Poisonings | 1.07 | 1 – 1.14 | 0.0384 | 1103 | 10730 | exclusion | phecode |
| 842 | Other sprains and strains | Injuries & Poisonings | 1.01 | 0.949 – 1.08 | 0.683 | 1021 | 9650 | exclusion | phecode |
| 850 | Hemorrhage or hematoma complicating a procedure | Injuries & Poisonings | 1.03 | 0.973 – 1.1 | 0.289 | 1263 | 13359 | exclusion | phecode |
| 851 |
Complications of transplants and reattachedComplications of transplants and reattached limbs
|
Injuries & Poisonings | 1.08 | 1.03 – 1.13 | 0.00212 | 1844 | 18159 | exclusion | phecode |
| 853 | Complication of colostomy or enterostomy | Injuries & Poisonings | 1.1 | 0.975 – 1.25 | 0.12 | 285 | 2977 | exclusion | phecode |
| 854 |
Complications of cardiac/vascular deviceComplications of cardiac/vascular device, implant, and graft
|
Injuries & Poisonings | 1.05 | 0.983 – 1.11 | 0.157 | 1188 | 12591 | exclusion | phecode |
| 855 |
Complication of nervous system device, implantComplication of nervous system device, implant, and graft
|
Injuries & Poisonings | 1.06 | 0.912 – 1.23 | 0.451 | 197 | 1759 | exclusion | phecode |
| 856 |
Vascular complications of surgery and medicalVascular complications of surgery and medical procedures
|
Injuries & Poisonings | 0.991 | 0.84 – 1.17 | 0.913 | 160 | 1828 | exclusion | phecode |
| 857 |
Mechanical complication of unspecifiedMechanical complication of unspecified genitourinary device, implant, and graft
|
Injuries & Poisonings | 1.04 | 0.972 – 1.12 | 0.235 | 841 | 8629 | exclusion | phecode |
| 858 | Complication of internal orthopedic device | Injuries & Poisonings | 1.05 | 0.998 – 1.11 | 0.0576 | 1503 | 14867 | exclusion | phecode |
| 859 |
Complication due to other implant and internalComplication due to other implant and internal device
|
Injuries & Poisonings | 1.09 | 1.03 – 1.15 | 0.00461 | 1330 | 13995 | exclusion | phecode |
| 860 | Bone marrow or stem cell transplant | Neoplasms | 0.881 | 0.714 – 1.09 | 0.236 | 97 | 1078 | exclusion | phecode |
| 870 | Open wounds of head; neck; and trunk | Injuries & Poisonings | 1.06 | 1.02 – 1.1 | 0.00699 | 2661 | 24499 | exclusion | phecode |
| 870.1 | Open wound or laceration of eye or eyelid | Injuries & Poisonings | 0.984 | 0.815 – 1.19 | 0.868 | 133 | 1321 | exclusion | phecode |
| 870.2 | Open wound of ear | Injuries & Poisonings | 1.18 | 0.951 – 1.46 | 0.133 | 98 | 956 | exclusion | phecode |
| 870.3 | Other open wound of head and face | Injuries & Poisonings | 1.05 | 0.983 – 1.13 | 0.141 | 899 | 8465 | exclusion | phecode |
| 870.4 | Open wound of nose and sinus | Injuries & Poisonings | 0.869 | 0.73 – 1.03 | 0.113 | 139 | 1292 | exclusion | phecode |
| 870.5 | Open wound of lip and mouth | Injuries & Poisonings | 1.11 | 0.944 – 1.3 | 0.208 | 186 | 1726 | exclusion | phecode |
| 870.6 | Open wound of neck | Injuries & Poisonings | 1.08 | 0.877 – 1.33 | 0.477 | 111 | 1222 | exclusion | phecode |
| 870.8 | Open wound of genital organs | Injuries & Poisonings | 0.927 | 0.749 – 1.15 | 0.488 | 97 | 985 | exclusion | phecode |
| 871 | Open wounds of extremities | Injuries & Poisonings | 1.03 | 0.987 – 1.08 | 0.166 | 2342 | 21843 | exclusion | phecode |
| 871.1 | Open wound of hand except finger(s) | Injuries & Poisonings | 0.972 | 0.873 – 1.08 | 0.604 | 390 | 3805 | exclusion | phecode |
| 871.2 | Open wound of finger(s) | Injuries & Poisonings | 0.998 | 0.92 – 1.08 | 0.954 | 680 | 6550 | exclusion | phecode |
| 871.3 | Open wound of foot except toe(s) alone | Injuries & Poisonings | 1.13 | 1 – 1.27 | 0.0503 | 328 | 3186 | exclusion | phecode |
| 871.4 | Open wound of toe(s) | Injuries & Poisonings | 1.06 | 0.908 – 1.24 | 0.456 | 195 | 1871 | exclusion | phecode |
| 872 | Traumatic amputation | Injuries & Poisonings | 1.19 | 1.07 – 1.33 | 0.00211 | 348 | 3482 | exclusion | phecode |
| 874 | Complication of amputation stump | Injuries & Poisonings | 1.32 | 1.07 – 1.61 | 0.00794 | 104 | 1074 | exclusion | phecode |
| 875 | Non-healing surgical wound | Injuries & Poisonings | 1.16 | 1.04 – 1.29 | 0.0071 | 378 | 3771 | exclusion | phecode |
| 876 |
Posttraumatic wound infection not elsewherePosttraumatic wound infection not elsewhere classified
|
Injuries & Poisonings | 1.06 | 0.97 – 1.16 | 0.192 | 527 | 5093 | exclusion | phecode |
| 907 | Injuries to the nervous system | Injuries & Poisonings | 1.08 | 0.995 – 1.17 | 0.0664 | 683 | 6801 | exclusion | phecode |
| 910 | Superficial injury, infected | Injuries & Poisonings | 0.838 | 0.664 – 1.06 | 0.138 | 85 | 775 | exclusion | phecode |
| 911 | Blister | Injuries & Poisonings | 1.05 | 0.908 – 1.22 | 0.506 | 210 | 1908 | exclusion | phecode |
| 912 | Insect bite | Injuries & Poisonings | 0.934 | 0.832 – 1.05 | 0.24 | 352 | 3249 | exclusion | phecode |
| 913 | Toxic effect of venom | Injuries & Poisonings | 1.07 | 0.935 – 1.23 | 0.313 | 231 | 2257 | exclusion | phecode |
| 916 | Contusion | Injuries & Poisonings | 1.02 | 0.983 – 1.06 | 0.266 | 2856 | 25447 | exclusion | phecode |
| 930 | Allergic reaction to food | Injuries & Poisonings | 0.951 | 0.87 – 1.04 | 0.272 | 552 | 5377 | exclusion | phecode |
| 931 |
Contact dermatitis and other eczema due toContact dermatitis and other eczema due to plants [except food]
|
Dermatologic | 0.87 | 0.791 – 0.956 | 0.00393 | 498 | 4769 | exclusion | phecode |
| 938 | Dermatitis due to solar radiation | Dermatologic | 0.91 | 0.877 – 0.944 | 6.85e-07 | 3593 | 18876 | exclusion | phecode |
| 938.1 | Acute dermatitis due to solar radiation | Dermatologic | 0.97 | 0.814 – 1.15 | 0.729 | 148 | 1453 | exclusion | phecode |
| 938.2 | Chronic dermatitis due to solar radiation | Dermatologic | 0.905 | 0.871 – 0.94 | 3.18e-07 | 3415 | 18520 | exclusion | phecode |
| 939 |
Atopic/contact dermatitis due to other orAtopic/contact dermatitis due to other or unspecified
|
Dermatologic | 0.964 | 0.932 – 0.997 | 0.0304 | 4557 | 21788 | exclusion | phecode |
| 939.1 | Contact and allergic dermatitis of eyelid | Dermatologic | 0.953 | 0.731 – 1.24 | 0.721 | 66 | 591 | exclusion | phecode |
| 941 | Adverse reaction to serum or vaccine | Injuries & Poisonings | 0.971 | 0.817 – 1.16 | 0.743 | 137 | 1252 | exclusion | phecode |
| 942 | Infusion and transfusion reaction | Injuries & Poisonings | 1.02 | 0.878 – 1.19 | 0.768 | 185 | 1786 | exclusion | phecode |
| 946 | Anaphylactic shock NOS | Injuries & Poisonings | 0.96 | 0.858 – 1.07 | 0.474 | 357 | 3301 | exclusion | phecode |
| 947 | Urticaria | Dermatologic | 0.967 | 0.899 – 1.04 | 0.372 | 837 | 8042 | exclusion | phecode |
| 949 | Allergies, other | Injuries & Poisonings | 0.977 | 0.946 – 1.01 | 0.161 | 4929 | 21756 | exclusion | phecode |
| 952 |
Spinal cord injury without evidence of spinalSpinal cord injury without evidence of spinal bone injury
|
Injuries & Poisonings | 1.15 | 1.02 – 1.29 | 0.0207 | 330 | 3333 | exclusion | phecode |
| 957 | Injury to other and unspecified nerves | Injuries & Poisonings | 1.04 | 0.837 – 1.3 | 0.709 | 93 | 944 | exclusion | phecode |
| 958 |
Certain early complications of trauma orCertain early complications of trauma or procedure
|
Injuries & Poisonings | 1.03 | 0.953 – 1.11 | 0.469 | 753 | 7933 | exclusion | phecode |
| 958.1 | Postoperative shock | Injuries & Poisonings | 1 | 0.807 – 1.25 | 0.972 | 97 | 1056 | exclusion | phecode |
| 958.2 | Traumatic and surgical subcutaneous emphysema | Injuries & Poisonings | 1.13 | 0.876 – 1.47 | 0.341 | 65 | 741 | exclusion | phecode |
| 960 | Poisoning by antibiotics | Injuries & Poisonings | 1.06 | 1 – 1.11 | 0.0479 | 1578 | 14595 | exclusion | phecode |
| 960.1 |
Adverse effects of antibacterials (notAdverse effects of antibacterials (not penicillins)
|
Injuries & Poisonings | 1.06 | 0.93 – 1.21 | 0.376 | 247 | 2211 | exclusion | phecode |
| 960.2 | Allergy/adverse effect of penicillin | Injuries & Poisonings | 1.01 | 0.946 – 1.08 | 0.758 | 1028 | 10583 | exclusion | phecode |
| 961 | Poisoning by other anti-infectives | Injuries & Poisonings | 1 | 0.896 – 1.12 | 0.998 | 370 | 3477 | exclusion | phecode |
| 961.1 | Poisoning/allergy of sulfonamides | Injuries & Poisonings | 1.04 | 0.954 – 1.12 | 0.398 | 655 | 6704 | exclusion | phecode |
| 962 | Poisoning by hormones and synthetic substitutes | Injuries & Poisonings | 0.992 | 0.903 – 1.09 | 0.87 | 497 | 5309 | exclusion | phecode |
| 962.1 |
Adrenal cortical steroids causing adverseAdrenal cortical steroids causing adverse effects in therapeutic use
|
Injuries & Poisonings | 0.987 | 0.858 – 1.14 | 0.857 | 228 | 2496 | exclusion | phecode |
| 962.2 |
Insulins and antidiabetic agents causingInsulins and antidiabetic agents causing adverse effects in therapeutic use
|
Injuries & Poisonings | 1.12 | 0.819 – 1.54 | 0.474 | 42 | 414 | exclusion | phecode |
| 962.3 |
Hormones and synthetic substitutes causingHormones and synthetic substitutes causing adverse effects in therapeutic use
|
Injuries & Poisonings | 0.992 | 0.876 – 1.12 | 0.898 | 291 | 3186 | exclusion | phecode |
| 963 | Poisoning by primarily systemic agents | Injuries & Poisonings | 1.01 | 0.961 – 1.07 | 0.639 | 1626 | 16031 | exclusion | phecode |
| 963.1 |
Antineoplastic and immunosuppressive drugsAntineoplastic and immunosuppressive drugs causing adverse effects
|
Injuries & Poisonings | 1.01 | 0.956 – 1.06 | 0.77 | 1583 | 15733 | exclusion | phecode |
| 964 |
Poisoning by agents primarily affecting bloodPoisoning by agents primarily affecting blood constituents
|
Injuries & Poisonings | 0.954 | 0.863 – 1.06 | 0.365 | 432 | 4512 | exclusion | phecode |
| 964.1 | Anticoagulants causing adverse effects | Injuries & Poisonings | 0.972 | 0.876 – 1.08 | 0.584 | 412 | 4289 | exclusion | phecode |
| 965 |
Poisoning by analgesics, antipyretics, andPoisoning by analgesics, antipyretics, and antirheumatics
|
Injuries & Poisonings | 1.09 | 1 – 1.2 | 0.0476 | 565 | 5810 | exclusion | phecode |
| 965.1 |
Opiates and related narcotics causing adverseOpiates and related narcotics causing adverse effects in therapeutic use
|
Injuries & Poisonings | 1.16 | 1.08 – 1.24 | 4.59e-05 | 927 | 9555 | exclusion | phecode |
| 965.3 |
Salicylates causing adverse effects inSalicylates causing adverse effects in therapeutic use
|
Injuries & Poisonings | 1.02 | 0.806 – 1.29 | 0.881 | 80 | 748 | exclusion | phecode |
| 966 |
Poisoning by anticonvulsants andPoisoning by anticonvulsants and anti-Parkinsonism drugs
|
Injuries & Poisonings | 0.999 | 0.781 – 1.28 | 0.992 | 71 | 646 | exclusion | phecode |
| 967 |
Adverse effects of sedatives or other centralAdverse effects of sedatives or other central nervous system depressants and anesthetics
|
Injuries & Poisonings | 1 | 0.934 – 1.08 | 0.92 | 861 | 8413 | exclusion | phecode |
| 969 | Poisoning by psychotropic agents | Injuries & Poisonings | 1.31 | 1.14 – 1.51 | 0.000187 | 219 | 1950 | exclusion | phecode |
| 971 |
Poisoning by drugs primarily affecting thePoisoning by drugs primarily affecting the autonomic nervous system
|
Injuries & Poisonings | 0.888 | 0.642 – 1.23 | 0.474 | 43 | 394 | exclusion | phecode |
| 972 |
Poisoning by agents primarily affecting thePoisoning by agents primarily affecting the cardiovascular system
|
Injuries & Poisonings | 1.07 | 0.919 – 1.26 | 0.366 | 173 | 1697 | exclusion | phecode |
| 972.1 |
Cardiac rhythm regulators causing adverseCardiac rhythm regulators causing adverse effects in therapeutic use
|
Injuries & Poisonings | 1.11 | 0.828 – 1.5 | 0.474 | 44 | 439 | exclusion | phecode |
| 972.6 | Antihypertensive agents causing adverse effects | Injuries & Poisonings | 1.07 | 0.822 – 1.39 | 0.614 | 60 | 616 | exclusion | phecode |
| 974 |
Poisoning by water, mineral, and uric acidPoisoning by water, mineral, and uric acid metabolism drugs
|
Injuries & Poisonings | 1.36 | 1.05 – 1.77 | 0.0208 | 65 | 708 | exclusion | phecode |
| 975 |
Poisoning by agents primarily acting on thePoisoning by agents primarily acting on the smooth and skeletal muscles and respiratory system
|
Injuries & Poisonings | 1 | 0.76 – 1.32 | 0.998 | 61 | 572 | exclusion | phecode |
| 976 |
Poisoning by agents primarily affecting skin &Poisoning by agents primarily affecting skin & mucous membrane, ophthalmological, otorhinolaryngological, & dental drugs
|
Injuries & Poisonings | 1.03 | 0.761 – 1.39 | 0.849 | 44 | 451 | exclusion | phecode |
| 977 | Personal history of allergy to medicinal agents | Injuries & Poisonings | 1 | 0.943 – 1.07 | 0.879 | 1099 | 10816 | exclusion | phecode |
| 979 | Adverse drug events and drug allergies | Injuries & Poisonings | 1.02 | 0.98 – 1.07 | 0.279 | 2306 | 20595 | exclusion | phecode |
| 980 |
Encounter for long-term (current) use ofEncounter for long-term (current) use of antibiotics
|
Infectious Diseases | 1.03 | 0.955 – 1.1 | 0.478 | 861 | 8547 | exclusion | phecode |
| 985 | Toxic effect of other metals | Injuries & Poisonings | 1.18 | 0.84 – 1.67 | 0.337 | 31 | 349 | exclusion | phecode |
| 989 |
Toxic effect of other substances, chieflyToxic effect of other substances, chiefly nonmedicinal as to source
|
Injuries & Poisonings | 1.17 | 0.937 – 1.46 | 0.167 | 87 | 853 | exclusion | phecode |
| 990 | Effects radiation NOS | Injuries & Poisonings | 1.04 | 0.991 – 1.08 | 0.121 | 2228 | 20109 | exclusion | phecode |
| 994 | Sepsis and SIRS | Injuries & Poisonings | 1.09 | 1.03 – 1.16 | 0.00413 | 1268 | 13628 | exclusion | phecode |
| 994.1 | Systemic inflammatory response syndrome (SIRS) | Injuries & Poisonings | 1.07 | 0.916 – 1.25 | 0.399 | 178 | 1911 | exclusion | phecode |
| 994.2 | Sepsis | Injuries & Poisonings | 1.09 | 1.02 – 1.15 | 0.00759 | 1204 | 12945 | exclusion | phecode |
| 994.21 | Septic shock | Injuries & Poisonings | 1.08 | 0.968 – 1.21 | 0.163 | 342 | 3876 | exclusion | phecode |