Plot overview
Signal overview
The plot gives a quick view of the currently visible associations. Click a point to pin its details, inspect that phecode across scans when both rows exist, or open the matching phecode detail page.
Evaluation cohort: Michigan Genomics Initiative Freeze 3 (MGI).
This page pairs the PheWAS plot with the full sortable table for the all-subject and exclusion scans.
Read the all-subject and exclusion scans separately. The combined view is only a browsing aid, and the selected-phecode panel below is only meaningful when the same phecode exists in both scans.
ExPRS exclusion definition
Exclusion cohort: individuals without Ever smoked.
For this ExPRS, the exclusion sensitivity scan removes individuals with the exposure itself before rerunning the PheWAS. This is an exposure-based sensitivity analysis rather than a diagnosis-based exclusion.
Plot overview
The plot gives a quick view of the currently visible associations. Click a point to pin its details, inspect that phecode across scans when both rows exist, or open the matching phecode detail page.
| Phecode | Description | Category | OR | 95% CI | P value | Cases | Controls | Analysis | Link |
|---|---|---|---|---|---|---|---|---|---|
| 008 | Intestinal infection | Infectious Diseases | 0.988 | 0.951 – 1.03 | 0.548 | 3004 | 29292 | all | phecode |
| 008.5 | Bacterial enteritis | Infectious Diseases | 0.989 | 0.934 – 1.05 | 0.717 | 1322 | 13162 | all | phecode |
| 008.52 | Intestinal infection due to C. difficile | Infectious Diseases | 0.993 | 0.931 – 1.06 | 0.835 | 1046 | 10455 | all | phecode |
| 008.6 | Viral Enteritis | Infectious Diseases | 1.05 | 0.975 – 1.13 | 0.19 | 770 | 7676 | all | phecode |
| 010 | Tuberculosis | Infectious Diseases | 0.977 | 0.853 – 1.12 | 0.741 | 244 | 2425 | all | phecode |
| 031 | Diseases due to other mycobacteria | Infectious Diseases | 1.09 | 0.878 – 1.36 | 0.426 | 86 | 855 | all | phecode |
| 038 | Septicemia | Infectious Diseases | 1.03 | 0.988 – 1.07 | 0.163 | 2582 | 24779 | all | phecode |
| 038.1 | Gram negative septicemia | Infectious Diseases | 1.04 | 0.956 – 1.14 | 0.346 | 568 | 5629 | all | phecode |
| 038.2 | Gram positive septicemia | Infectious Diseases | 1.05 | 0.915 – 1.2 | 0.497 | 235 | 2350 | all | phecode |
| 038.3 | Bacteremia | Infectious Diseases | 1.03 | 0.97 – 1.09 | 0.328 | 1210 | 12079 | all | phecode |
| 041 | Bacterial infection NOS | Infectious Diseases | 1.03 | 0.997 – 1.05 | 0.0859 | 5750 | 38799 | all | phecode |
| 041.1 | Staphylococcus infections | Infectious Diseases | 0.999 | 0.95 – 1.05 | 0.972 | 1707 | 16977 | all | phecode |
| 041.11 | Methicillin sensitive Staphylococcus aureus | Infectious Diseases | 1.01 | 0.942 – 1.08 | 0.813 | 920 | 9192 | all | phecode |
| 041.12 | Methicillin resistant Staphylococcus aureus | Infectious Diseases | 0.987 | 0.917 – 1.06 | 0.727 | 783 | 7812 | all | phecode |
| 041.2 | Streptococcus infection | Infectious Diseases | 1.04 | 0.988 – 1.09 | 0.136 | 1632 | 16287 | all | phecode |
| 041.21 | Rheumatic fever / chorea | Infectious Diseases | 0.976 | 0.858 – 1.11 | 0.712 | 257 | 2554 | all | phecode |
| 041.4 | E. coli | Infectious Diseases | 1.1 | 1.04 – 1.17 | 0.00195 | 1175 | 11680 | all | phecode |
| 041.8 | H. pylori | Infectious Diseases | 1.09 | 0.958 – 1.24 | 0.188 | 257 | 2521 | all | phecode |
| 041.9 | Infection with drug-resistant microorganisms | Infectious Diseases | 1.04 | 0.937 – 1.15 | 0.461 | 387 | 3864 | all | phecode |
| 053 | Herpes zoster | Infectious Diseases | 1.03 | 0.977 – 1.09 | 0.267 | 1560 | 15184 | all | phecode |
| 053.1 | Herpes zoster with nervous system complications | Infectious Diseases | 1.06 | 0.923 – 1.22 | 0.416 | 220 | 2169 | all | phecode |
| 054 | Herpes simplex | Infectious Diseases | 1.03 | 0.98 – 1.09 | 0.226 | 1593 | 15600 | all | phecode |
| 070 | Viral hepatitis | Infectious Diseases | 1.19 | 1.11 – 1.28 | 3.18e-06 | 829 | 8280 | all | phecode |
| 070.1 | Viral hepatitis A | Infectious Diseases | 0.97 | 0.773 – 1.22 | 0.789 | 87 | 860 | all | phecode |
| 070.2 | Viral hepatitis B | Infectious Diseases | 1.04 | 0.9 – 1.2 | 0.611 | 215 | 2138 | all | phecode |
| 070.3 | Viral hepatitis C | Infectious Diseases | 1.29 | 1.18 – 1.42 | 4.82e-08 | 528 | 5280 | all | phecode |
| 070.4 | Chronic hepatitis | Infectious Diseases | 1.07 | 0.923 – 1.24 | 0.364 | 197 | 1964 | all | phecode |
| 070.9 | Hepatitis NOS | Infectious Diseases | 1.09 | 1.03 – 1.16 | 0.00527 | 1145 | 11381 | all | phecode |
| 071 | Human immunodeficiency virus [HIV] disease | Infectious Diseases | 1.08 | 0.906 – 1.28 | 0.398 | 145 | 1450 | all | phecode |
| 071.1 | HIV infection, symptomatic | Infectious Diseases | 1.06 | 0.876 – 1.28 | 0.556 | 117 | 1163 | all | phecode |
| 078 | Viral warts & HPV | Infectious Diseases | 1.01 | 0.978 – 1.05 | 0.469 | 3434 | 29624 | all | phecode |
| 079 | Viral infection | Infectious Diseases | 0.995 | 0.969 – 1.02 | 0.74 | 6664 | 35342 | all | phecode |
| 079.1 | Varicella infection | Infectious Diseases | 0.993 | 0.96 – 1.03 | 0.708 | 3793 | 31251 | all | phecode |
| 079.2 | Infectious mononucleosis | Infectious Diseases | 1.15 | 1.02 – 1.31 | 0.0252 | 283 | 2723 | all | phecode |
| 079.9 | Viremia, NOS | Infectious Diseases | 1.06 | 0.981 – 1.14 | 0.147 | 838 | 8253 | all | phecode |
| 080 | Postoperative infection | Infectious Diseases | 1.06 | 1.02 – 1.11 | 0.00254 | 2619 | 26065 | all | phecode |
| 081 |
Infection/inflammation of internal prostheticInfection/inflammation of internal prosthetic device; implant; and graft
|
Infectious Diseases | 0.991 | 0.941 – 1.04 | 0.733 | 1589 | 15884 | all | phecode |
| 090 |
Sexually transmitted infections (not HIV orSexually transmitted infections (not HIV or hepatitis)
|
Infectious Diseases | 1.05 | 0.983 – 1.13 | 0.142 | 965 | 9630 | all | phecode |
| 110 | Dermatophytosis / Dermatomycosis | Infectious Diseases | 1.02 | 0.987 – 1.06 | 0.205 | 3544 | 30054 | all | phecode |
| 110.1 | Dermatophytosis | Infectious Diseases | 1.02 | 0.981 – 1.06 | 0.347 | 3241 | 27244 | all | phecode |
| 110.11 | Dermatophytosis of nail | Infectious Diseases | 1.03 | 0.984 – 1.08 | 0.195 | 2044 | 16765 | all | phecode |
| 110.12 | Althete's foot | Infectious Diseases | 0.988 | 0.921 – 1.06 | 0.733 | 899 | 8043 | all | phecode |
| 110.13 | Dermatophytosis of the body | Infectious Diseases | 1.01 | 0.936 – 1.09 | 0.836 | 790 | 7827 | all | phecode |
| 110.2 | Dermatomycoses | Infectious Diseases | 1.07 | 0.967 – 1.19 | 0.184 | 398 | 3971 | all | phecode |
| 112 | Candidiasis | Infectious Diseases | 1.01 | 0.977 – 1.05 | 0.523 | 3685 | 30495 | all | phecode |
| 112.3 | Candidiasis of skin and nails | Infectious Diseases | 1.05 | 0.969 – 1.14 | 0.233 | 682 | 6732 | all | phecode |
| 117 | Mycoses | Infectious Diseases | 0.973 | 0.895 – 1.06 | 0.525 | 608 | 6069 | all | phecode |
| 117.1 | Histoplasmosis | Infectious Diseases | 1.12 | 0.896 – 1.4 | 0.322 | 81 | 801 | all | phecode |
| 117.4 | Aspergillosis | Infectious Diseases | 0.948 | 0.795 – 1.13 | 0.553 | 140 | 1387 | all | phecode |
| 130 | Spirochetal infection | Infectious Diseases | 1.08 | 0.916 – 1.27 | 0.364 | 168 | 1677 | all | phecode |
| 130.1 | Lyme disease | Infectious Diseases | 0.985 | 0.815 – 1.19 | 0.879 | 116 | 1160 | all | phecode |
| 131 | Protozoan infection | Infectious Diseases | 0.958 | 0.736 – 1.25 | 0.752 | 61 | 610 | all | phecode |
| 132 | Infestation (lice, mites) | Infectious Diseases | 1.02 | 0.874 – 1.18 | 0.831 | 195 | 1948 | all | phecode |
| 134 | Helminthiases | Infectious Diseases | 1.06 | 0.845 – 1.33 | 0.616 | 83 | 812 | all | phecode |
| 134.1 | Intestinal helminthiases | Infectious Diseases | 1.04 | 0.783 – 1.38 | 0.783 | 53 | 513 | all | phecode |
| 136 | Other infectious and parasitic diseases | Infectious Diseases | 1.03 | 0.994 – 1.07 | 0.0987 | 3279 | 32486 | all | phecode |
| 145 | Cancer of mouth | Neoplasms | 0.974 | 0.923 – 1.03 | 0.33 | 1481 | 14725 | all | phecode |
| 145.1 | Cancer of lip | Neoplasms | 0.983 | 0.774 – 1.25 | 0.889 | 76 | 750 | all | phecode |
| 145.2 | Cancer of tongue | Neoplasms | 0.949 | 0.876 – 1.03 | 0.205 | 645 | 6430 | all | phecode |
| 145.3 | Cancer of major salivary glands | Neoplasms | 0.954 | 0.856 – 1.06 | 0.395 | 361 | 3597 | all | phecode |
| 145.4 | Cancer of the gums | Neoplasms | 0.935 | 0.796 – 1.1 | 0.417 | 166 | 1632 | all | phecode |
| 145.5 | Cancer of the mouth floor | Neoplasms | 1.04 | 0.902 – 1.2 | 0.582 | 206 | 2048 | all | phecode |
| 149 | Cancer of larynx, pharynx, nasal cavities | Neoplasms | 0.979 | 0.924 – 1.04 | 0.466 | 1290 | 12873 | all | phecode |
| 149.1 | Cancer of oropharynx | Neoplasms | 0.96 | 0.859 – 1.07 | 0.465 | 350 | 3499 | all | phecode |
| 149.2 | Cancer of nasopharynx | Neoplasms | 1.08 | 0.88 – 1.32 | 0.469 | 100 | 1000 | all | phecode |
| 149.3 | Cancer of hypopharynx | Neoplasms | 1.16 | 0.926 – 1.45 | 0.197 | 82 | 819 | all | phecode |
| 149.4 | Cancer of larynx | Neoplasms | 0.998 | 0.899 – 1.11 | 0.963 | 386 | 3857 | all | phecode |
| 149.5 |
Hx of malignant neoplasm of oral cavity andHx of malignant neoplasm of oral cavity and pharynx
|
Neoplasms | 0.982 | 0.899 – 1.07 | 0.684 | 552 | 5505 | all | phecode |
| 149.9 | Cancer of of nasal cavities | Neoplasms | 1.03 | 0.905 – 1.18 | 0.63 | 240 | 2398 | all | phecode |
| 150 | Cancer of esophagus | Neoplasms | 1.02 | 0.927 – 1.13 | 0.654 | 433 | 4315 | all | phecode |
| 151 | Cancer of stomach | Neoplasms | 0.97 | 0.884 – 1.06 | 0.515 | 498 | 4962 | all | phecode |
| 153 | Colorectal cancer | Neoplasms | 1 | 0.947 – 1.06 | 0.99 | 1458 | 14383 | all | phecode |
| 153.2 | Colon cancer | Neoplasms | 1.02 | 0.957 – 1.08 | 0.589 | 1160 | 11472 | all | phecode |
| 153.3 |
Malignant neoplasm of rectum, rectosigmoidMalignant neoplasm of rectum, rectosigmoid junction, and anus
|
Neoplasms | 0.984 | 0.915 – 1.06 | 0.675 | 815 | 8093 | all | phecode |
| 155 | Cancer of liver and intrahepatic bile duct | Neoplasms | 1.06 | 0.964 – 1.16 | 0.233 | 511 | 5097 | all | phecode |
| 155.1 | Malignant neoplasm of liver, primary | Neoplasms | 1.09 | 0.975 – 1.22 | 0.126 | 344 | 3433 | all | phecode |
| 157 | Pancreatic cancer | Neoplasms | 0.96 | 0.875 – 1.05 | 0.383 | 503 | 5005 | all | phecode |
| 158 |
Neoplasm of unspecified nature of digestiveNeoplasm of unspecified nature of digestive system
|
Neoplasms | 0.986 | 0.937 – 1.04 | 0.603 | 1623 | 15759 | all | phecode |
| 159 |
Malignant neoplasm of other and ill-definedMalignant neoplasm of other and ill-defined sites within the digestive organs and peritoneum
|
Neoplasms | 0.987 | 0.94 – 1.04 | 0.6 | 1818 | 17869 | all | phecode |
| 159.2 |
Malignant neoplasm of small intestineMalignant neoplasm of small intestine, including duodenum
|
Neoplasms | 0.873 | 0.763 – 0.999 | 0.0486 | 221 | 2206 | all | phecode |
| 159.3 |
Malignant neoplasm of gallbladder andMalignant neoplasm of gallbladder and extrahepatic bile ducts
|
Neoplasms | 0.991 | 0.843 – 1.16 | 0.907 | 158 | 1578 | all | phecode |
| 159.4 |
Malignant neoplasm of retroperitoneum andMalignant neoplasm of retroperitoneum and peritoneum
|
Neoplasms | 1.02 | 0.906 – 1.16 | 0.712 | 293 | 2920 | all | phecode |
| 164 | Cancer of intrathoracic organs | Neoplasms | 1 | 0.837 – 1.19 | 0.998 | 133 | 1324 | all | phecode |
| 165 | Cancer within the respiratory system | Neoplasms | 1.04 | 0.982 – 1.1 | 0.186 | 1336 | 13340 | all | phecode |
| 165.1 | Cancer of bronchus; lung | Neoplasms | 1.05 | 0.986 – 1.12 | 0.125 | 1057 | 10552 | all | phecode |
| 170 | Cancer of bone and connective tissue | Neoplasms | 0.958 | 0.912 – 1.01 | 0.093 | 1792 | 17850 | all | phecode |
| 170.1 | Bone cancer | Neoplasms | 0.96 | 0.89 – 1.04 | 0.287 | 773 | 7690 | all | phecode |
| 170.2 | Cancer of connective tissue | Neoplasms | 0.951 | 0.896 – 1.01 | 0.0944 | 1266 | 12632 | all | phecode |
| 172 | Skin cancer | Neoplasms | 0.981 | 0.957 – 1.01 | 0.142 | 8608 | 33186 | all | phecode |
| 172.1 | Melanomas of skin, dx or hx | Neoplasms | 0.971 | 0.942 – 1 | 0.0572 | 5330 | 30106 | all | phecode |
| 172.11 | Melanomas of skin | Neoplasms | 0.978 | 0.942 – 1.02 | 0.244 | 3100 | 25064 | all | phecode |
| 172.2 | Other non-epithelial cancer of skin | Neoplasms | 0.976 | 0.95 – 1 | 0.0787 | 7095 | 30462 | all | phecode |
| 172.21 | Basal cell carcinoma | Neoplasms | 0.971 | 0.937 – 1.01 | 0.0988 | 3690 | 23868 | all | phecode |
| 172.22 | Squamous cell carcinoma | Neoplasms | 0.987 | 0.945 – 1.03 | 0.539 | 2414 | 17683 | all | phecode |
| 172.3 | Carcinoma in situ of skin | Neoplasms | 0.969 | 0.918 – 1.02 | 0.262 | 1482 | 12326 | all | phecode |
| 173 | Neoplasm of uncertain behavior of skin | Neoplasms | 0.99 | 0.945 – 1.04 | 0.677 | 1997 | 18755 | all | phecode |
| 174 | Breast cancer | Neoplasms | 0.992 | 0.954 – 1.03 | 0.705 | 3186 | 15514 | all | phecode |
| 174.1 | Breast cancer [female] | Neoplasms | 0.993 | 0.953 – 1.03 | 0.716 | 3036 | 14701 | all | phecode |
| 174.11 | Malignant neoplasm of female breast | Neoplasms | 0.991 | 0.952 – 1.03 | 0.674 | 2991 | 14639 | all | phecode |
| 174.3 | Neoplasm of uncertain behavior of breast | Neoplasms | 0.866 | 0.754 – 0.994 | 0.0403 | 233 | 2307 | all | phecode |
| 175 | Acquired absence of breast | Neoplasms | 0.934 | 0.871 – 1 | 0.0565 | 919 | 8920 | all | phecode |
| 180 | Cervical cancer and dysplasia | Neoplasms | 1.01 | 0.959 – 1.07 | 0.637 | 1431 | 12185 | all | phecode |
| 180.1 | Cervical cancer | Neoplasms | 0.965 | 0.879 – 1.06 | 0.457 | 500 | 4982 | all | phecode |
| 180.3 |
Cervical intraepithelial neoplasia [CIN]Cervical intraepithelial neoplasia [CIN] [Cervical dysplasia]
|
Neoplasms | 1.06 | 0.993 – 1.13 | 0.0796 | 1048 | 9323 | all | phecode |
| 182 | Malignant neoplasm of uterus | Neoplasms | 0.924 | 0.857 – 0.996 | 0.0399 | 765 | 7613 | all | phecode |
| 184 | Cancer of other female genital organs | Neoplasms | 0.983 | 0.925 – 1.04 | 0.587 | 1191 | 11592 | all | phecode |
| 184.1 |
Malignant neoplasm of ovary and other uterineMalignant neoplasm of ovary and other uterine adnexa
|
Neoplasms | 0.986 | 0.904 – 1.08 | 0.752 | 573 | 5719 | all | phecode |
| 184.11 | Malignant neoplasm of ovary | Neoplasms | 0.933 | 0.844 – 1.03 | 0.173 | 432 | 4309 | all | phecode |
| 184.2 |
Cancer of other female genital organsCancer of other female genital organs (excluding uterus and ovary)
|
Neoplasms | 1.01 | 0.925 – 1.09 | 0.878 | 608 | 6057 | all | phecode |
| 185 | Cancer of prostate | Neoplasms | 0.988 | 0.946 – 1.03 | 0.584 | 2901 | 10342 | all | phecode |
| 187 | Cancer of other male genital organs | Neoplasms | 1.06 | 0.944 – 1.19 | 0.33 | 339 | 3384 | all | phecode |
| 187.1 |
Malignant neoplasm of unspecified male genitalMalignant neoplasm of unspecified male genital organ
|
Neoplasms | 1.07 | 0.877 – 1.29 | 0.524 | 115 | 1141 | all | phecode |
| 187.2 | Malignant neoplasm of testis | Neoplasms | 1.01 | 0.866 – 1.17 | 0.921 | 183 | 1830 | all | phecode |
| 187.8 |
Neoplasm of uncertain behavior of male genitalNeoplasm of uncertain behavior of male genital organs
|
Neoplasms | 1.04 | 0.786 – 1.38 | 0.785 | 57 | 562 | all | phecode |
| 189 |
Cancer of urinary organs (incl. kidney andCancer of urinary organs (incl. kidney and bladder)
|
Neoplasms | 1.05 | 1.01 – 1.09 | 0.0122 | 2923 | 23541 | all | phecode |
| 189.1 | Cancer of kidney and renal pelvis | Neoplasms | 1.05 | 0.991 – 1.11 | 0.105 | 1450 | 14437 | all | phecode |
| 189.11 | Malignant neoplasm of kidney, except pelvis | Neoplasms | 1.07 | 1.01 – 1.13 | 0.0252 | 1267 | 12655 | all | phecode |
| 189.12 | Malignant neoplasm of renal pelvis | Neoplasms | 0.943 | 0.825 – 1.08 | 0.395 | 237 | 2347 | all | phecode |
| 189.2 | Cancer of bladder | Neoplasms | 1.06 | 1.01 – 1.12 | 0.0139 | 1783 | 15224 | all | phecode |
| 189.21 | Malignant neoplasm of bladder | Neoplasms | 1.07 | 1.02 – 1.13 | 0.00829 | 1657 | 14178 | all | phecode |
| 189.4 | Malignant neoplasm of other urinary organs | Neoplasms | 1.04 | 0.962 – 1.13 | 0.31 | 678 | 6586 | all | phecode |
| 190 | Cancer of eye | Neoplasms | 1.01 | 0.854 – 1.2 | 0.887 | 138 | 1374 | all | phecode |
| 191 |
Manlignant and unknown neoplasms of brain andManlignant and unknown neoplasms of brain and nervous system
|
Neoplasms | 0.984 | 0.923 – 1.05 | 0.616 | 1078 | 10771 | all | phecode |
| 191.1 | Cancer of brain and nervous system | Neoplasms | 0.964 | 0.892 – 1.04 | 0.36 | 706 | 7052 | all | phecode |
| 191.11 | Cancer of brain | Neoplasms | 0.963 | 0.885 – 1.05 | 0.383 | 600 | 5996 | all | phecode |
| 193 | Thyroid cancer | Neoplasms | 0.985 | 0.92 – 1.05 | 0.671 | 945 | 9393 | all | phecode |
| 194 | Cancer of other endocrine glands | Neoplasms | 1.02 | 0.934 – 1.11 | 0.674 | 579 | 5759 | all | phecode |
| 195 | Cancer, suspected or other | Neoplasms | 0.997 | 0.976 – 1.02 | 0.759 | 16962 | 26401 | all | phecode |
| 195.1 | Malignant neoplasm, other | Neoplasms | 0.995 | 0.974 – 1.02 | 0.664 | 16670 | 26384 | all | phecode |
| 195.3 | Malignant neoplasm of head, face, and neck | Neoplasms | 0.993 | 0.932 – 1.06 | 0.816 | 1103 | 9766 | all | phecode |
| 196 | Radiotherapy | Neoplasms | 0.984 | 0.943 – 1.03 | 0.477 | 2427 | 17006 | all | phecode |
| 197 | Chemotherapy | Neoplasms | 0.988 | 0.957 – 1.02 | 0.462 | 4952 | 23797 | all | phecode |
| 198 | Secondary malignant neoplasm | Neoplasms | 1.02 | 0.985 – 1.05 | 0.331 | 5801 | 23481 | all | phecode |
| 198.1 | Secondary malignancy of lymph nodes | Neoplasms | 0.995 | 0.959 – 1.03 | 0.765 | 3677 | 21489 | all | phecode |
| 198.2 | Secondary malignancy of respiratory organs | Neoplasms | 1.04 | 0.98 – 1.11 | 0.179 | 1072 | 10334 | all | phecode |
| 198.3 |
Secondary malignant neoplasm of digestiveSecondary malignant neoplasm of digestive systems
|
Neoplasms | 0.935 | 0.872 – 1 | 0.0617 | 866 | 8538 | all | phecode |
| 198.4 | Secondary malignant neoplasm of liver | Neoplasms | 0.961 | 0.891 – 1.04 | 0.305 | 767 | 7558 | all | phecode |
| 198.5 | Secondary malignancy of brain/spine | Neoplasms | 1.04 | 0.956 – 1.13 | 0.363 | 640 | 6338 | all | phecode |
| 198.6 | Secondary malignancy of bone | Neoplasms | 0.972 | 0.906 – 1.04 | 0.439 | 866 | 8307 | all | phecode |
| 198.7 | Secondary malignant neoplasm of skin | Neoplasms | 0.936 | 0.836 – 1.05 | 0.245 | 336 | 3253 | all | phecode |
| 199 | Neoplasm of uncertain behavior | Neoplasms | 1.01 | 0.983 – 1.04 | 0.405 | 5693 | 25767 | all | phecode |
| 199.4 | Neurofibromatosis | Neoplasms | 1.15 | 0.922 – 1.43 | 0.214 | 88 | 880 | all | phecode |
| 200 | Myeloproliferative disease | Neoplasms | 0.953 | 0.896 – 1.01 | 0.134 | 1113 | 11098 | all | phecode |
| 200.1 | Polycythemia vera | Neoplasms | 0.896 | 0.781 – 1.03 | 0.115 | 231 | 2310 | all | phecode |
| 201 | Hodgkin's disease | Neoplasms | 1.1 | 0.939 – 1.3 | 0.229 | 172 | 1705 | all | phecode |
| 202 | Cancer of other lymphoid, histiocytic tissue | Neoplasms | 0.985 | 0.935 – 1.04 | 0.574 | 1559 | 15571 | all | phecode |
| 202.2 | Non-Hodgkins lymphoma | Neoplasms | 0.987 | 0.933 – 1.05 | 0.663 | 1329 | 13268 | all | phecode |
| 202.21 | Nodular lymphoma | Neoplasms | 0.963 | 0.89 – 1.04 | 0.354 | 693 | 6923 | all | phecode |
| 202.22 | Reticulosarcoma | Neoplasms | 1.12 | 0.957 – 1.31 | 0.156 | 170 | 1693 | all | phecode |
| 202.24 | Large cell lymphoma | Neoplasms | 1.07 | 0.915 – 1.26 | 0.384 | 160 | 1586 | all | phecode |
| 204 | Leukemia | Neoplasms | 0.974 | 0.9 – 1.05 | 0.508 | 689 | 6876 | all | phecode |
| 204.1 | Lymphoid leukemia | Neoplasms | 0.978 | 0.856 – 1.12 | 0.743 | 236 | 2354 | all | phecode |
| 204.11 | Lymphoid leukemia, acute | Neoplasms | 0.992 | 0.792 – 1.24 | 0.947 | 74 | 734 | all | phecode |
| 204.12 | Lymphoid leukemia, chronic | Neoplasms | 1.02 | 0.876 – 1.2 | 0.76 | 173 | 1724 | all | phecode |
| 204.2 | Myeloid leukemia | Neoplasms | 1.09 | 0.964 – 1.24 | 0.17 | 265 | 2633 | all | phecode |
| 204.21 | Myeloid leukemia, acute | Neoplasms | 1.1 | 0.936 – 1.29 | 0.247 | 153 | 1516 | all | phecode |
| 204.22 | Myeloid leukemia, chronic | Neoplasms | 0.959 | 0.746 – 1.23 | 0.746 | 61 | 610 | all | phecode |
| 204.4 | Multiple myeloma | Neoplasms | 0.855 | 0.742 – 0.985 | 0.0303 | 217 | 2162 | all | phecode |
| 208 | Benign neoplasm of colon | Neoplasms | 1 | 0.982 – 1.03 | 0.694 | 10303 | 34953 | all | phecode |
| 209 | Neuroendocrine tumors | Neoplasms | 0.95 | 0.834 – 1.08 | 0.444 | 258 | 2580 | all | phecode |
| 210 | Benign neoplasm of lip, oral cavity, and pharynx | Neoplasms | 0.997 | 0.951 – 1.05 | 0.9 | 1891 | 18839 | all | phecode |
| 211 |
Benign neoplasm of other parts of digestiveBenign neoplasm of other parts of digestive system
|
Neoplasms | 0.981 | 0.957 – 1.01 | 0.152 | 7329 | 36606 | all | phecode |
| 212 |
Benign neoplasm of respiratory andBenign neoplasm of respiratory and intrathoracic organs
|
Neoplasms | 1.02 | 0.975 – 1.07 | 0.341 | 1843 | 18412 | all | phecode |
| 213 | Benign neoplasm of bone and articular cartilage | Neoplasms | 0.985 | 0.936 – 1.04 | 0.571 | 1677 | 15527 | all | phecode |
| 214 | Lipoma | Neoplasms | 1.03 | 0.972 – 1.08 | 0.348 | 1437 | 14132 | all | phecode |
| 214.1 | Lipoma of skin and subcutaneous tissue | Neoplasms | 1.01 | 0.938 – 1.08 | 0.84 | 883 | 8710 | all | phecode |
| 215 |
Other benign neoplasm of connective and otherOther benign neoplasm of connective and other soft tissue
|
Neoplasms | 1.01 | 0.977 – 1.04 | 0.613 | 4528 | 39509 | all | phecode |
| 216 | Benign neoplasm of skin | Neoplasms | 0.986 | 0.965 – 1.01 | 0.213 | 11528 | 34919 | all | phecode |
| 216.1 | Screening for malignant neoplasms of the skin | Neoplasms | 1.04 | 0.889 – 1.21 | 0.654 | 174 | 1701 | all | phecode |
| 217 | Vascular hamartomas and non-neoplastic nevi | Neoplasms | 0.949 | 0.903 – 0.997 | 0.0373 | 1786 | 17184 | all | phecode |
| 217.1 | Nevus, non-neoplastic | Neoplasms | 0.945 | 0.898 – 0.994 | 0.0292 | 1679 | 16116 | all | phecode |
| 218 | Benign neoplasm of uterus | Neoplasms | 0.978 | 0.945 – 1.01 | 0.209 | 4301 | 16661 | all | phecode |
| 218.1 | Uterine leiomyoma | Neoplasms | 1.02 | 0.967 – 1.07 | 0.515 | 1835 | 15733 | all | phecode |
| 218.2 | Other benign neoplasm of uterus | Neoplasms | 0.955 | 0.92 – 0.992 | 0.0172 | 3403 | 16447 | all | phecode |
| 220 | Benign neoplasm of ovary | Neoplasms | 0.947 | 0.883 – 1.02 | 0.127 | 893 | 8783 | all | phecode |
| 221 | Benign neoplasm of other female genital organs | Neoplasms | 1 | 0.954 – 1.05 | 0.995 | 2042 | 14248 | all | phecode |
| 222 | Benign neoplasm of male genital organs | Neoplasms | 0.978 | 0.919 – 1.04 | 0.481 | 1133 | 10663 | all | phecode |
| 223 |
Benign neoplasm of kidney and other urinaryBenign neoplasm of kidney and other urinary organs
|
Neoplasms | 1.02 | 0.969 – 1.07 | 0.471 | 1801 | 12657 | all | phecode |
| 224 | Benign neoplasm of eye | Neoplasms | 0.965 | 0.891 – 1.04 | 0.374 | 691 | 6752 | all | phecode |
| 224.1 | Benign neoplasm of eye, uveal | Neoplasms | 0.946 | 0.868 – 1.03 | 0.199 | 595 | 5773 | all | phecode |
| 225 |
Benign neoplasm of brain and other parts ofBenign neoplasm of brain and other parts of nervous system
|
Neoplasms | 0.965 | 0.909 – 1.03 | 0.251 | 1209 | 12074 | all | phecode |
| 225.1 |
Benign neoplasm of brain, cranial nervesBenign neoplasm of brain, cranial nerves, meninges
|
Neoplasms | 0.979 | 0.915 – 1.05 | 0.538 | 947 | 9454 | all | phecode |
| 225.2 | Benign neoplasm of spinal cord, meninges | Neoplasms | 0.956 | 0.845 – 1.08 | 0.479 | 289 | 2890 | all | phecode |
| 226 | Benign neoplasm of thyroid glands | Neoplasms | 0.971 | 0.917 – 1.03 | 0.316 | 1329 | 13264 | all | phecode |
| 227 |
Benign neoplasm of other endocrine glands andBenign neoplasm of other endocrine glands and related structures
|
Neoplasms | 0.988 | 0.939 – 1.04 | 0.64 | 1690 | 16896 | all | phecode |
| 227.1 | Benign neoplasm of adrenal gland | Neoplasms | 1.04 | 0.946 – 1.14 | 0.413 | 467 | 4644 | all | phecode |
| 227.2 | Benign neoplasm of parathyroid gland | Neoplasms | 0.978 | 0.908 – 1.05 | 0.549 | 795 | 7941 | all | phecode |
| 227.3 |
Benign neoplasm of pituitary gland andBenign neoplasm of pituitary gland and craniopharyngeal duct (pouch)
|
Neoplasms | 0.979 | 0.885 – 1.08 | 0.672 | 435 | 4350 | all | phecode |
| 228 | Hemangioma and lymphangioma, any site | Neoplasms | 0.973 | 0.93 – 1.02 | 0.244 | 2149 | 20946 | all | phecode |
| 228.1 | Hemangioma of skin and subcutaneous tissue | Neoplasms | 0.983 | 0.929 – 1.04 | 0.562 | 1356 | 13336 | all | phecode |
| 229 | Benign neoplasm of unspecified sites | Neoplasms | 0.995 | 0.97 – 1.02 | 0.671 | 7767 | 36615 | all | phecode |
| 229.1 | Benign neoplasm of lymph nodes | Neoplasms | 1.01 | 0.977 – 1.03 | 0.72 | 5743 | 34218 | all | phecode |
| 240 | Simple and unspecified goiter | Endocrine/metabolic | 0.966 | 0.906 – 1.03 | 0.302 | 1031 | 9761 | all | phecode |
| 241 | Nontoxic nodular goiter | Endocrine/metabolic | 0.993 | 0.955 – 1.03 | 0.744 | 2910 | 22227 | all | phecode |
| 241.1 | Nontoxic uninodular goiter | Endocrine/metabolic | 1.02 | 0.977 – 1.07 | 0.346 | 2265 | 19902 | all | phecode |
| 241.2 | Nontoxic multinodular goiter | Endocrine/metabolic | 0.958 | 0.904 – 1.02 | 0.147 | 1304 | 12479 | all | phecode |
| 242 | Thyrotoxicosis with or without goiter | Endocrine/metabolic | 1 | 0.948 – 1.06 | 0.936 | 1400 | 13425 | all | phecode |
| 242.1 | Graves' disease | Endocrine/metabolic | 1.02 | 0.929 – 1.12 | 0.698 | 515 | 5068 | all | phecode |
| 242.2 | Toxic multinodular goiter | Endocrine/metabolic | 0.927 | 0.769 – 1.12 | 0.427 | 124 | 1224 | all | phecode |
| 242.3 | Exophthalmos | Endocrine/metabolic | 0.958 | 0.848 – 1.08 | 0.492 | 292 | 2898 | all | phecode |
| 242.31 | Thyrotoxic exophthalmos | Endocrine/metabolic | 0.943 | 0.789 – 1.13 | 0.519 | 144 | 1432 | all | phecode |
| 244 | Hypothyroidism | Endocrine/metabolic | 0.994 | 0.969 – 1.02 | 0.641 | 8099 | 32717 | all | phecode |
| 244.1 | Secondary hypothyroidism | Endocrine/metabolic | 0.981 | 0.933 – 1.03 | 0.445 | 1762 | 17230 | all | phecode |
| 244.2 | Acquired hypothyroidism | Endocrine/metabolic | 0.981 | 0.925 – 1.04 | 0.518 | 1261 | 11982 | all | phecode |
| 244.4 | Hypothyroidism NOS | Endocrine/metabolic | 0.995 | 0.969 – 1.02 | 0.691 | 7542 | 32208 | all | phecode |
| 245 | Thyroiditis | Endocrine/metabolic | 1.01 | 0.941 – 1.09 | 0.754 | 832 | 7882 | all | phecode |
| 245.2 | Chronic thyroiditis | Endocrine/metabolic | 0.958 | 0.885 – 1.04 | 0.292 | 686 | 6517 | all | phecode |
| 245.21 | Chronic lymphocytic thyroiditis | Endocrine/metabolic | 0.956 | 0.882 – 1.04 | 0.265 | 679 | 6449 | all | phecode |
| 246 | Other disorders of thyroid | Endocrine/metabolic | 0.99 | 0.962 – 1.02 | 0.476 | 6129 | 30240 | all | phecode |
| 246.2 | Thyroid cyst | Endocrine/metabolic | 1.1 | 0.89 – 1.35 | 0.387 | 101 | 960 | all | phecode |
| 246.7 | Abnormal results of function study of thyroid | Endocrine/metabolic | 0.957 | 0.892 – 1.03 | 0.213 | 886 | 8696 | all | phecode |
| 249 | Secondary diabetes mellitus | Endocrine/metabolic | 0.969 | 0.904 – 1.04 | 0.377 | 1150 | 8340 | all | phecode |
| 250 | Diabetes mellitus | Endocrine/metabolic | 0.991 | 0.97 – 1.01 | 0.428 | 13947 | 31815 | all | phecode |
| 250.1 | Type 1 diabetes | Endocrine/metabolic | 0.991 | 0.934 – 1.05 | 0.752 | 2364 | 11758 | all | phecode |
| 250.11 | Type 1 diabetes with ketoacidosis | Endocrine/metabolic | 0.982 | 0.826 – 1.17 | 0.837 | 262 | 960 | all | phecode |
| 250.12 | Type 1 diabetes with renal manifestations | Endocrine/metabolic | 1.03 | 0.92 – 1.16 | 0.598 | 551 | 2686 | all | phecode |
| 250.13 | Type 1 diabetes with ophthalmic manifestations | Endocrine/metabolic | 0.974 | 0.874 – 1.09 | 0.638 | 784 | 3018 | all | phecode |
| 250.14 | Type 1 diabetes with neurological manifestations | Endocrine/metabolic | 1.05 | 0.935 – 1.17 | 0.421 | 638 | 2675 | all | phecode |
| 250.15 |
Diabetes type 1 with peripheral circulatoryDiabetes type 1 with peripheral circulatory disorders
|
Endocrine/metabolic | 0.999 | 0.832 – 1.2 | 0.994 | 155 | 850 | all | phecode |
| 250.2 | Type 2 diabetes | Endocrine/metabolic | 0.997 | 0.972 – 1.02 | 0.803 | 9843 | 29688 | all | phecode |
| 250.21 | Type 2 diabetes with ketoacidosis | Endocrine/metabolic | 1.06 | 0.906 – 1.24 | 0.474 | 282 | 1327 | all | phecode |
| 250.22 | Type 2 diabetes with renal manifestations | Endocrine/metabolic | 0.97 | 0.919 – 1.02 | 0.271 | 1941 | 13510 | all | phecode |
| 250.23 | Type 2 diabetes with ophthalmic manifestations | Endocrine/metabolic | 1.03 | 0.964 – 1.1 | 0.402 | 1643 | 9668 | all | phecode |
| 250.24 | Type 2 diabetes with neurological manifestations | Endocrine/metabolic | 1.01 | 0.963 – 1.06 | 0.647 | 2557 | 16502 | all | phecode |
| 250.25 |
Diabetes type 2 with peripheral circulatoryDiabetes type 2 with peripheral circulatory disorders
|
Endocrine/metabolic | 0.899 | 0.83 – 0.974 | 0.00942 | 860 | 6143 | all | phecode |
| 250.3 | Insulin pump user | Endocrine/metabolic | 1.02 | 0.973 – 1.06 | 0.477 | 3496 | 20809 | all | phecode |
| 250.4 | Abnormal glucose | Endocrine/metabolic | 0.988 | 0.962 – 1.01 | 0.375 | 8385 | 30645 | all | phecode |
| 250.41 | Impaired fasting glucose | Endocrine/metabolic | 0.973 | 0.925 – 1.02 | 0.293 | 1870 | 15861 | all | phecode |
| 250.42 | Other abnormal glucose | Endocrine/metabolic | 0.99 | 0.963 – 1.02 | 0.499 | 7553 | 30071 | all | phecode |
| 250.5 | Glycosuria or Acetonuria | Endocrine/metabolic | 0.984 | 0.823 – 1.18 | 0.861 | 136 | 1067 | all | phecode |
| 250.6 | Polyneuropathy in diabetes | Endocrine/metabolic | 1.04 | 0.986 – 1.1 | 0.14 | 2132 | 13390 | all | phecode |
| 250.7 | Diabetic retinopathy | Endocrine/metabolic | 1.03 | 0.977 – 1.09 | 0.257 | 1691 | 10517 | all | phecode |
| 251 | Other disorders of pancreatic internal secretion | Endocrine/metabolic | 0.989 | 0.926 – 1.06 | 0.756 | 991 | 8469 | all | phecode |
| 251.1 | Hypoglycemia | Endocrine/metabolic | 0.992 | 0.926 – 1.06 | 0.828 | 1207 | 8570 | all | phecode |
| 252 | Disorders of parathyroid gland | Endocrine/metabolic | 0.995 | 0.953 – 1.04 | 0.835 | 2282 | 22119 | all | phecode |
| 252.1 | Hyperparathyroidism | Endocrine/metabolic | 0.991 | 0.947 – 1.04 | 0.707 | 2088 | 20335 | all | phecode |
| 252.2 | Hypoparathyroidism | Endocrine/metabolic | 0.967 | 0.882 – 1.06 | 0.479 | 508 | 5073 | all | phecode |
| 253 |
Disorders of the pituitary gland and itsDisorders of the pituitary gland and its hypothalamic control
|
Endocrine/metabolic | 1.01 | 0.939 – 1.08 | 0.836 | 859 | 8544 | all | phecode |
| 253.1 | Pituitary hyperfunction | Endocrine/metabolic | 0.989 | 0.874 – 1.12 | 0.864 | 263 | 2621 | all | phecode |
| 253.11 | Acromegaly and gigantism | Endocrine/metabolic | 0.974 | 0.775 – 1.22 | 0.818 | 83 | 826 | all | phecode |
| 253.2 | Pituitary hypofunction | Endocrine/metabolic | 1.04 | 0.908 – 1.2 | 0.556 | 226 | 2250 | all | phecode |
| 253.3 | Diabetes insipidus | Endocrine/metabolic | 1.12 | 0.901 – 1.39 | 0.307 | 86 | 860 | all | phecode |
| 253.4 | Anterior pituitary disorders | Endocrine/metabolic | 0.936 | 0.78 – 1.12 | 0.481 | 121 | 1209 | all | phecode |
| 253.7 | Other disorders of neurohypophysis | Endocrine/metabolic | 1.11 | 0.91 – 1.35 | 0.304 | 108 | 1080 | all | phecode |
| 255 | Disorders of adrenal glands | Endocrine/metabolic | 0.989 | 0.937 – 1.04 | 0.674 | 1506 | 14869 | all | phecode |
| 255.1 | Adrenal hyperfunction | Endocrine/metabolic | 1 | 0.899 – 1.11 | 0.999 | 373 | 3730 | all | phecode |
| 255.11 | Cushing's syndrome | Endocrine/metabolic | 0.994 | 0.855 – 1.16 | 0.939 | 183 | 1830 | all | phecode |
| 255.12 | Hyperaldosteronism | Endocrine/metabolic | 0.973 | 0.818 – 1.16 | 0.76 | 135 | 1350 | all | phecode |
| 255.2 | Adrenal hypofunction | Endocrine/metabolic | 0.988 | 0.91 – 1.07 | 0.783 | 626 | 6239 | all | phecode |
| 255.21 | Glucocorticoid deficiency | Endocrine/metabolic | 1.01 | 0.929 – 1.1 | 0.79 | 596 | 5941 | all | phecode |
| 256 | Ovarian dysfunction | Endocrine/metabolic | 0.928 | 0.872 – 0.988 | 0.0194 | 1146 | 10513 | all | phecode |
| 256.4 | Polycystic ovaries | Endocrine/metabolic | 0.911 | 0.844 – 0.985 | 0.0186 | 742 | 7128 | all | phecode |
| 257 | Testicular dysfunction | Endocrine/metabolic | 0.999 | 0.935 – 1.07 | 0.967 | 1015 | 9238 | all | phecode |
| 257.1 | Testicular hypofunction | Endocrine/metabolic | 0.996 | 0.932 – 1.07 | 0.913 | 983 | 8933 | all | phecode |
| 258 | Iatrogenic endocrine disorders | Endocrine/metabolic | 1.08 | 0.871 – 1.33 | 0.492 | 91 | 910 | all | phecode |
| 258.1 | Postablative ovarian failure | Endocrine/metabolic | 0.825 | 0.673 – 1.01 | 0.0667 | 109 | 1090 | all | phecode |
| 259 | Other endocrine disorders | Endocrine/metabolic | 0.996 | 0.934 – 1.06 | 0.904 | 1038 | 10259 | all | phecode |
| 260 | Protein-calorie malnutrition | Endocrine/metabolic | 1 | 0.966 – 1.04 | 0.81 | 2880 | 26812 | all | phecode |
| 260.1 | Cachexia | Endocrine/metabolic | 1.06 | 0.94 – 1.2 | 0.331 | 292 | 2911 | all | phecode |
| 260.2 | severe protein-calorie malnutrition | Endocrine/metabolic | 1.02 | 0.973 – 1.08 | 0.355 | 1691 | 16847 | all | phecode |
| 260.22 | Nutritional marasmus | Endocrine/metabolic | 0.99 | 0.909 – 1.08 | 0.82 | 614 | 6140 | all | phecode |
| 260.3 | Adult failure to thrive | Endocrine/metabolic | 1.07 | 0.987 – 1.17 | 0.0976 | 629 | 6236 | all | phecode |
| 260.6 | Anorexia | Endocrine/metabolic | 1.03 | 0.958 – 1.1 | 0.443 | 868 | 8591 | all | phecode |
| 260.7 | Polyphagia | Endocrine/metabolic | 0.988 | 0.764 – 1.28 | 0.929 | 65 | 643 | all | phecode |
| 261 | Vitamin deficiency | Endocrine/metabolic | 0.99 | 0.965 – 1.02 | 0.455 | 7718 | 35203 | all | phecode |
| 261.1 | Vitamin A deficiency | Endocrine/metabolic | 0.904 | 0.705 – 1.16 | 0.428 | 69 | 690 | all | phecode |
| 261.2 | Vitamin B-complex deficiencies | Endocrine/metabolic | 1.02 | 0.947 – 1.09 | 0.649 | 857 | 8405 | all | phecode |
| 261.4 | Vitamin D deficiency | Endocrine/metabolic | 0.988 | 0.963 – 1.01 | 0.39 | 7255 | 35225 | all | phecode |
| 261.41 | Rickets or osteomalacia | Endocrine/metabolic | 1.02 | 0.78 – 1.33 | 0.898 | 52 | 511 | all | phecode |
| 262 | Mineral deficiency NEC | Endocrine/metabolic | 0.938 | 0.883 – 0.996 | 0.0381 | 1182 | 11676 | all | phecode |
| 263 | Other nutritional deficiency | Endocrine/metabolic | 0.983 | 0.934 – 1.04 | 0.521 | 1651 | 15788 | all | phecode |
| 264 | Lack of normal physiological development | Endocrine/metabolic | 1.05 | 0.918 – 1.2 | 0.474 | 239 | 2301 | all | phecode |
| 264.2 | Failure to thrive (childhood) | Endocrine/metabolic | 1.07 | 0.885 – 1.29 | 0.488 | 122 | 1220 | all | phecode |
| 264.9 |
Lack of normal physiological developmentLack of normal physiological development, unspecified
|
Endocrine/metabolic | 1.08 | 0.851 – 1.36 | 0.537 | 81 | 772 | all | phecode |
| 269 | Proteinuria | Endocrine/metabolic | 0.993 | 0.943 – 1.05 | 0.798 | 1694 | 13981 | all | phecode |
| 270 |
Disorders of protein plasma/amino-acidDisorders of protein plasma/amino-acid transport and metabolism
|
Endocrine/metabolic | 0.958 | 0.895 – 1.02 | 0.21 | 967 | 9575 | all | phecode |
| 270.1 | Disturbances of amino-acid transport | Endocrine/metabolic | 0.955 | 0.81 – 1.13 | 0.586 | 170 | 1697 | all | phecode |
| 270.11 |
Disturbances of sulphur-bearing amino-acidDisturbances of sulphur-bearing amino-acid metabolism
|
Endocrine/metabolic | 0.996 | 0.828 – 1.2 | 0.963 | 134 | 1334 | all | phecode |
| 270.2 | Disorders of amino-acid metabolism | Endocrine/metabolic | 0.939 | 0.764 – 1.15 | 0.545 | 96 | 954 | all | phecode |
| 270.3 | Disorders of plasma protein metabolism | Endocrine/metabolic | 0.953 | 0.882 – 1.03 | 0.216 | 737 | 7303 | all | phecode |
| 270.32 | Paraproteinemia | Endocrine/metabolic | 0.897 | 0.805 – 1 | 0.0505 | 384 | 3781 | all | phecode |
| 270.33 | Amyloidosis | Endocrine/metabolic | 0.933 | 0.726 – 1.2 | 0.585 | 71 | 695 | all | phecode |
| 270.34 | Alpha-1-antitrypsin deficiency | Endocrine/metabolic | 1.19 | 0.94 – 1.51 | 0.147 | 69 | 690 | all | phecode |
| 270.38 |
Other specified disorders of plasma proteinOther specified disorders of plasma protein metabolism
|
Endocrine/metabolic | 0.987 | 0.876 – 1.11 | 0.829 | 299 | 2984 | all | phecode |
| 271 |
Disorders of carbohydrate transport andDisorders of carbohydrate transport and metabolism
|
Endocrine/metabolic | 0.987 | 0.949 – 1.03 | 0.503 | 2907 | 28132 | all | phecode |
| 271.3 |
Intestinal disaccharidase deficiencies andIntestinal disaccharidase deficiencies and disaccharide malabsorption
|
Endocrine/metabolic | 0.985 | 0.946 – 1.02 | 0.443 | 2827 | 27425 | all | phecode |
| 271.9 |
Other disorders of carbohydrate transport andOther disorders of carbohydrate transport and metabolism
|
Endocrine/metabolic | 0.922 | 0.749 – 1.14 | 0.445 | 102 | 1007 | all | phecode |
| 272 | Disorders of lipoid metabolism | Endocrine/metabolic | 1.02 | 0.996 – 1.04 | 0.123 | 18881 | 26670 | all | phecode |
| 272.1 | Hyperlipidemia | Endocrine/metabolic | 1.02 | 0.996 – 1.04 | 0.124 | 18843 | 26654 | all | phecode |
| 272.11 | Hypercholesterolemia | Endocrine/metabolic | 1.01 | 0.979 – 1.04 | 0.551 | 5928 | 21600 | all | phecode |
| 272.12 | Hyperglyceridemia | Endocrine/metabolic | 0.986 | 0.931 – 1.04 | 0.627 | 1360 | 11837 | all | phecode |
| 272.13 | Mixed hyperlipidemia | Endocrine/metabolic | 1.01 | 0.975 – 1.05 | 0.485 | 3538 | 18449 | all | phecode |
| 272.9 | Unspecified disorder of lipoid metabolism | Endocrine/metabolic | 0.86 | 0.767 – 0.965 | 0.0105 | 313 | 3011 | all | phecode |
| 274 | Gout and other crystal arthropathies | Endocrine/metabolic | 1.01 | 0.969 – 1.05 | 0.634 | 2524 | 22729 | all | phecode |
| 274.1 | Gout | Endocrine/metabolic | 1.01 | 0.966 – 1.05 | 0.717 | 2409 | 21991 | all | phecode |
| 274.11 | Gouty arthropathy | Endocrine/metabolic | 0.993 | 0.932 – 1.06 | 0.823 | 1082 | 10576 | all | phecode |
| 274.2 | Crystal arthropathies | Endocrine/metabolic | 1.03 | 0.893 – 1.2 | 0.655 | 195 | 1890 | all | phecode |
| 274.21 | Chondrocalcinosis | Endocrine/metabolic | 1.03 | 0.883 – 1.19 | 0.729 | 183 | 1772 | all | phecode |
| 275 | Disorders of mineral metabolism | Endocrine/metabolic | 0.984 | 0.953 – 1.02 | 0.334 | 4357 | 37091 | all | phecode |
| 275.1 | Disorders of iron metabolism | Hematopoietic | 0.947 | 0.825 – 1.09 | 0.444 | 218 | 2180 | all | phecode |
| 275.11 | Hereditary hemochromatosis | Hematopoietic | 0.991 | 0.804 – 1.22 | 0.933 | 99 | 990 | all | phecode |
| 275.2 | Disorders of copper metabolism | Endocrine/metabolic | 1.01 | 0.784 – 1.31 | 0.919 | 62 | 614 | all | phecode |
| 275.3 | Disorders of magnesium metabolism | Endocrine/metabolic | 1.03 | 0.969 – 1.1 | 0.34 | 1154 | 11504 | all | phecode |
| 275.5 | Disorders of calcium/phosphorus metabolism | Endocrine/metabolic | 0.975 | 0.94 – 1.01 | 0.162 | 3369 | 31544 | all | phecode |
| 275.51 | Hypocalcemia | Endocrine/metabolic | 0.953 | 0.889 – 1.02 | 0.172 | 898 | 8969 | all | phecode |
| 275.53 | Disorders of phosphorus metabolism | Endocrine/metabolic | 0.993 | 0.939 – 1.05 | 0.804 | 1366 | 13634 | all | phecode |
| 275.6 | Hypercalcemia | Endocrine/metabolic | 0.976 | 0.924 – 1.03 | 0.37 | 1468 | 14183 | all | phecode |
| 276 |
Disorders of fluid, electrolyte, and acid-baseDisorders of fluid, electrolyte, and acid-base balance
|
Endocrine/metabolic | 0.998 | 0.975 – 1.02 | 0.852 | 9238 | 37046 | all | phecode |
| 276.1 | Electrolyte imbalance | Endocrine/metabolic | 1.01 | 0.978 – 1.03 | 0.694 | 6352 | 34366 | all | phecode |
| 276.11 | Hyperosmolality and/or hypernatremia | Endocrine/metabolic | 0.951 | 0.871 – 1.04 | 0.263 | 550 | 5434 | all | phecode |
| 276.12 | Hyposmolality and/or hyponatremia | Endocrine/metabolic | 1.03 | 0.986 – 1.07 | 0.201 | 2514 | 23219 | all | phecode |
| 276.13 | Hyperpotassemia | Endocrine/metabolic | 1.02 | 0.979 – 1.06 | 0.39 | 2992 | 25216 | all | phecode |
| 276.14 | Hypopotassemia | Endocrine/metabolic | 0.994 | 0.95 – 1.04 | 0.782 | 2148 | 20909 | all | phecode |
| 276.4 | Acid-base balance disorder | Endocrine/metabolic | 1.03 | 0.982 – 1.08 | 0.235 | 2086 | 20332 | all | phecode |
| 276.41 | Acidosis | Endocrine/metabolic | 1.01 | 0.966 – 1.07 | 0.571 | 1788 | 17572 | all | phecode |
| 276.42 | Alkalosis | Endocrine/metabolic | 1.02 | 0.93 – 1.12 | 0.651 | 476 | 4741 | all | phecode |
| 276.5 | Hypovolemia | Endocrine/metabolic | 0.987 | 0.957 – 1.02 | 0.418 | 4574 | 34527 | all | phecode |
| 276.6 | Fluid overload | Endocrine/metabolic | 1.03 | 0.972 – 1.09 | 0.332 | 1384 | 13211 | all | phecode |
| 276.8 | Polydipsia | Endocrine/metabolic | 0.761 | 0.632 – 0.916 | 0.0039 | 124 | 1240 | all | phecode |
| 277 | Other disorders of metabolism | Endocrine/metabolic | 0.989 | 0.957 – 1.02 | 0.501 | 4112 | 35070 | all | phecode |
| 277.2 |
Other disorders of purine and pyrimidineOther disorders of purine and pyrimidine metabolism
|
Endocrine/metabolic | 1.05 | 0.943 – 1.16 | 0.387 | 403 | 3991 | all | phecode |
| 277.4 | Disorders of bilirubin excretion | Endocrine/metabolic | 1.03 | 0.949 – 1.11 | 0.528 | 720 | 7161 | all | phecode |
| 277.5 | Other disorders of lipoid metabolism | Endocrine/metabolic | 0.981 | 0.916 – 1.05 | 0.577 | 936 | 9270 | all | phecode |
| 277.51 | Lipoprotein disorders | Endocrine/metabolic | 0.99 | 0.919 – 1.07 | 0.8 | 773 | 7668 | all | phecode |
| 277.7 | Dysmetabolic syndrome X | Endocrine/metabolic | 0.979 | 0.914 – 1.05 | 0.556 | 916 | 8359 | all | phecode |
| 278 | Overweight, obesity and other hyperalimentation | Endocrine/metabolic | 1.03 | 1.01 – 1.05 | 0.00442 | 19419 | 27331 | all | phecode |
| 278.1 | Obesity | Endocrine/metabolic | 1.03 | 1.01 – 1.05 | 0.0035 | 17129 | 27321 | all | phecode |
| 278.11 | Morbid obesity | Endocrine/metabolic | 1.03 | 1 – 1.05 | 0.0531 | 8280 | 27172 | all | phecode |
| 278.3 | Localized adiposity | Endocrine/metabolic | 1.09 | 0.974 – 1.23 | 0.129 | 324 | 3228 | all | phecode |
| 278.4 | Abnormal weight gain | Endocrine/metabolic | 1.01 | 0.968 – 1.06 | 0.568 | 2104 | 17411 | all | phecode |
| 279 | Disorders involving the immune mechanism | Endocrine/metabolic | 0.969 | 0.932 – 1.01 | 0.107 | 2934 | 28612 | all | phecode |
| 279.1 | Immunity deficiency | Endocrine/metabolic | 0.956 | 0.9 – 1.02 | 0.153 | 1161 | 11571 | all | phecode |
| 279.11 | Deficiency of humoral immunity | Endocrine/metabolic | 0.898 | 0.802 – 1.01 | 0.0651 | 330 | 3278 | all | phecode |
| 279.2 | Autoimmune disease NEC | Endocrine/metabolic | 0.953 | 0.883 – 1.03 | 0.209 | 754 | 7516 | all | phecode |
| 279.7 | Other immunological findings | Endocrine/metabolic | 0.995 | 0.965 – 1.03 | 0.757 | 4885 | 36552 | all | phecode |
| 279.8 |
Other specified disorders involving the immuneOther specified disorders involving the immune mechanism
|
Endocrine/metabolic | 0.932 | 0.856 – 1.01 | 0.103 | 601 | 5988 | all | phecode |
| 280 | Iron deficiency anemias | Hematopoietic | 0.996 | 0.965 – 1.03 | 0.8 | 4626 | 30873 | all | phecode |
| 280.1 |
Iron deficiency anemias, unspecified or not dueIron deficiency anemias, unspecified or not due to blood loss
|
Hematopoietic | 0.992 | 0.96 – 1.02 | 0.608 | 4484 | 30649 | all | phecode |
| 280.2 |
Iron deficiency anemia secondary to blood lossIron deficiency anemia secondary to blood loss (chronic)
|
Hematopoietic | 0.986 | 0.939 – 1.04 | 0.585 | 1771 | 17196 | all | phecode |
| 281 | Other deficiency anemia | Hematopoietic | 1.03 | 0.94 – 1.12 | 0.546 | 519 | 5120 | all | phecode |
| 281.1 | Megaloblastic anemia | Hematopoietic | 1.05 | 0.925 – 1.19 | 0.448 | 253 | 2497 | all | phecode |
| 281.11 | Pernicious anemia | Hematopoietic | 1.16 | 0.965 – 1.4 | 0.112 | 114 | 1108 | all | phecode |
| 281.12 | Other vitamin B12 deficiency anemia | Hematopoietic | 1.14 | 0.981 – 1.31 | 0.0879 | 187 | 1817 | all | phecode |
| 281.9 | Deficiency anemias | Hematopoietic | 0.986 | 0.873 – 1.11 | 0.826 | 285 | 2830 | all | phecode |
| 282 | Hereditary hemolytic anemias | Hematopoietic | 0.886 | 0.789 – 0.996 | 0.0425 | 323 | 3188 | all | phecode |
| 282.8 | Other hemoglobinopathies | Hematopoietic | 0.781 | 0.674 – 0.904 | 0.000959 | 216 | 2113 | all | phecode |
| 282.9 | Other hereditary hemolytic anemias | Hematopoietic | 0.895 | 0.771 – 1.04 | 0.142 | 192 | 1920 | all | phecode |
| 283 | Acquired hemolytic anemias | Hematopoietic | 0.936 | 0.794 – 1.1 | 0.43 | 155 | 1550 | all | phecode |
| 283.1 | Autoimmune hemolytic anemias | Hematopoietic | 0.976 | 0.749 – 1.27 | 0.858 | 64 | 633 | all | phecode |
| 284 | Aplastic anemia | Hematopoietic | 0.995 | 0.921 – 1.08 | 0.906 | 697 | 6943 | all | phecode |
| 284.1 | Pancytopenia | Hematopoietic | 0.993 | 0.914 – 1.08 | 0.864 | 612 | 6100 | all | phecode |
| 285 | Other anemias | Hematopoietic | 1 | 0.979 – 1.02 | 0.993 | 11794 | 33591 | all | phecode |
| 285.1 | Acute posthemorrhagic anemia | Hematopoietic | 1 | 0.967 – 1.04 | 0.875 | 3325 | 27709 | all | phecode |
| 285.2 | Anemia of chronic disease | Hematopoietic | 0.972 | 0.928 – 1.02 | 0.227 | 2055 | 19939 | all | phecode |
| 285.21 | Anemia in chronic kidney disease | Hematopoietic | 1.01 | 0.939 – 1.08 | 0.883 | 932 | 9106 | all | phecode |
| 285.22 | Anemia in neoplastic disease | Hematopoietic | 0.963 | 0.889 – 1.04 | 0.348 | 690 | 6892 | all | phecode |
| 286 | Coagulation defects | Hematopoietic | 0.965 | 0.933 – 0.998 | 0.0385 | 3844 | 33384 | all | phecode |
| 286.1 | Congenital coagulation defects | Hematopoietic | 1.01 | 0.88 – 1.15 | 0.923 | 250 | 2466 | all | phecode |
| 286.11 | Von willebrand's disease | Hematopoietic | 0.974 | 0.776 – 1.22 | 0.82 | 83 | 822 | all | phecode |
| 286.12 |
Congenital deficiency of other clotting factorsCongenital deficiency of other clotting factors (including factor VII)
|
Hematopoietic | 1.02 | 0.845 – 1.23 | 0.825 | 126 | 1260 | all | phecode |
| 286.2 |
Encounter for long-term (current) use ofEncounter for long-term (current) use of anticoagulants
|
Hematopoietic | 0.984 | 0.949 – 1.02 | 0.402 | 3354 | 25918 | all | phecode |
| 286.3 |
Coagulation defects complicating pregnancy orCoagulation defects complicating pregnancy or postpartum
|
Hematopoietic | 0.939 | 0.763 – 1.16 | 0.556 | 97 | 962 | all | phecode |
| 286.4 | Acquired coagulation factor deficiency | Hematopoietic | 0.963 | 0.846 – 1.1 | 0.568 | 254 | 2529 | all | phecode |
| 286.5 |
Hemorrhagic disorder due to intrinsicHemorrhagic disorder due to intrinsic circulating anticoagulants
|
Hematopoietic | 1.09 | 0.914 – 1.31 | 0.326 | 132 | 1294 | all | phecode |
| 286.6 | Defibrination syndrome | Hematopoietic | 0.971 | 0.932 – 1.01 | 0.156 | 2579 | 25377 | all | phecode |
| 286.7 | Other and unspecified coagulation defects | Hematopoietic | 0.967 | 0.931 – 1 | 0.0831 | 3014 | 29294 | all | phecode |
| 286.8 | Hypercoagulable state | Hematopoietic | 0.97 | 0.904 – 1.04 | 0.404 | 846 | 8437 | all | phecode |
| 286.81 | Primary hypercoagulable state | Hematopoietic | 0.982 | 0.913 – 1.06 | 0.619 | 813 | 8111 | all | phecode |
| 286.9 | Abnormal coagulation profile | Hematopoietic | 0.967 | 0.911 – 1.03 | 0.284 | 1182 | 11487 | all | phecode |
| 287 | Purpura and other hemorrhagic conditions | Hematopoietic | 0.998 | 0.962 – 1.03 | 0.901 | 3288 | 28474 | all | phecode |
| 287.1 | Spontaneous ecchymoses | Hematopoietic | 0.908 | 0.784 – 1.05 | 0.198 | 211 | 2094 | all | phecode |
| 287.3 | Thrombocytopenia | Hematopoietic | 0.999 | 0.961 – 1.04 | 0.957 | 2938 | 26323 | all | phecode |
| 287.31 | Primary thrombocytopenia | Hematopoietic | 0.987 | 0.908 – 1.07 | 0.766 | 601 | 5994 | all | phecode |
| 287.32 | Secondary thrombocytopenia | Hematopoietic | 0.991 | 0.907 – 1.08 | 0.835 | 569 | 5686 | all | phecode |
| 287.4 | Qualitative platelet defects | Hematopoietic | 1.04 | 0.851 – 1.26 | 0.72 | 112 | 1120 | all | phecode |
| 288 | Diseases of white blood cells | Hematopoietic | 0.99 | 0.96 – 1.02 | 0.505 | 4886 | 36527 | all | phecode |
| 288.1 | Decreased white blood cell count | Hematopoietic | 0.948 | 0.9 – 0.999 | 0.0478 | 1599 | 15951 | all | phecode |
| 288.11 | Neutropenia | Hematopoietic | 0.981 | 0.921 – 1.04 | 0.546 | 1106 | 11041 | all | phecode |
| 288.2 | Elevated white blood cell count | Hematopoietic | 0.992 | 0.96 – 1.03 | 0.654 | 4082 | 35079 | all | phecode |
| 288.3 | Eosinophilia | Hematopoietic | 0.885 | 0.758 – 1.03 | 0.124 | 187 | 1866 | all | phecode |
| 289 | Other diseases of blood and blood-forming organs | Hematopoietic | 0.961 | 0.915 – 1.01 | 0.118 | 1757 | 17434 | all | phecode |
| 289.3 |
Personal history of diseases of blood andPersonal history of diseases of blood and blood-forming organs
|
Hematopoietic | 0.992 | 0.926 – 1.06 | 0.81 | 918 | 9087 | all | phecode |
| 289.4 | Lymphadenitis | Hematopoietic | 1.02 | 0.985 – 1.05 | 0.269 | 3888 | 34715 | all | phecode |
| 289.5 | Diseases of spleen | Hematopoietic | 1.05 | 0.947 – 1.17 | 0.338 | 393 | 3913 | all | phecode |
| 289.8 | Polycythemia, secondary | Hematopoietic | 0.902 | 0.791 – 1.03 | 0.123 | 255 | 2550 | all | phecode |
| 289.9 | Abnormality of red blood cells | Hematopoietic | 0.955 | 0.859 – 1.06 | 0.388 | 385 | 3813 | all | phecode |
| 290 |
Delirium dementia and amnestic and otherDelirium dementia and amnestic and other cognitive disorders
|
Mental Disorders | 0.985 | 0.93 – 1.04 | 0.611 | 1318 | 11547 | all | phecode |
| 290.1 | Dementias | Mental Disorders | 0.971 | 0.889 – 1.06 | 0.514 | 541 | 4910 | all | phecode |
| 290.11 | Alzheimer's disease | Mental Disorders | 0.906 | 0.766 – 1.07 | 0.249 | 151 | 1389 | all | phecode |
| 290.12 | Dementia with cerebral degenerations | Mental Disorders | 0.939 | 0.755 – 1.17 | 0.573 | 88 | 846 | all | phecode |
| 290.13 | Senile dementia | Mental Disorders | 1.01 | 0.902 – 1.13 | 0.892 | 340 | 3078 | all | phecode |
| 290.16 | Vascular dementia | Mental Disorders | 0.992 | 0.792 – 1.24 | 0.945 | 81 | 777 | all | phecode |
| 290.2 | Delirium due to conditions classified elsewhere | Mental Disorders | 0.99 | 0.917 – 1.07 | 0.791 | 750 | 7358 | all | phecode |
| 290.3 |
Other persistent mental disorders due toOther persistent mental disorders due to conditions classified elsewhere
|
Mental Disorders | 0.993 | 0.927 – 1.06 | 0.843 | 886 | 8618 | all | phecode |
| 291 |
Other specified nonpsychotic and/or transientOther specified nonpsychotic and/or transient mental disorders
|
Mental Disorders | 1.03 | 0.986 – 1.07 | 0.204 | 2550 | 24810 | all | phecode |
| 291.1 |
Transient mental disorders due to conditionsTransient mental disorders due to conditions classified elsewhere
|
Mental Disorders | 1.17 | 0.998 – 1.37 | 0.0525 | 175 | 1750 | all | phecode |
| 291.4 |
Specific nonpsychotic mental disorders due toSpecific nonpsychotic mental disorders due to brain damage
|
Mental Disorders | 1.02 | 0.927 – 1.12 | 0.698 | 484 | 4807 | all | phecode |
| 291.8 | Alteration of consciousness | Mental Disorders | 1.03 | 0.982 – 1.08 | 0.228 | 2036 | 19974 | all | phecode |
| 292 | Neurological disorders | Mental Disorders | 1.01 | 0.983 – 1.04 | 0.458 | 5733 | 38553 | all | phecode |
| 292.1 | Aphasia/speech disturbance | Mental Disorders | 1.02 | 0.969 – 1.06 | 0.526 | 2013 | 19867 | all | phecode |
| 292.11 | Aphasia | Mental Disorders | 0.989 | 0.913 – 1.07 | 0.793 | 664 | 6581 | all | phecode |
| 292.12 | Symbolic dysfunction | Mental Disorders | 0.854 | 0.737 – 0.99 | 0.0361 | 200 | 1988 | all | phecode |
| 292.2 | Mild cognitive impairment | Mental Disorders | 1 | 0.901 – 1.11 | 0.998 | 389 | 3731 | all | phecode |
| 292.3 | Memory loss | Mental Disorders | 0.97 | 0.925 – 1.02 | 0.207 | 1922 | 18158 | all | phecode |
| 292.4 | Altered mental status | Mental Disorders | 1.03 | 0.987 – 1.07 | 0.179 | 2454 | 22725 | all | phecode |
| 292.5 | Transient alteration of awareness | Mental Disorders | 1.05 | 0.95 – 1.16 | 0.335 | 430 | 4285 | all | phecode |
| 292.6 | Hallucinations | Mental Disorders | 1 | 0.873 – 1.16 | 0.948 | 217 | 2147 | all | phecode |
| 293 | Symptoms involving head and neck | Mental Disorders | 0.931 | 0.841 – 1.03 | 0.17 | 414 | 4127 | all | phecode |
| 293.1 |
Swelling, mass, or lump in head and neckSwelling, mass, or lump in head and neck [Space-occupying lesion, intracranial NOS]
|
Mental Disorders | 1 | 0.97 – 1.03 | 0.92 | 4417 | 38609 | all | phecode |
| 295 | Schizophrenia and other psychotic disorders | Mental Disorders | 1.07 | 0.995 – 1.15 | 0.0673 | 885 | 8229 | all | phecode |
| 295.1 | Schizophrenia | Mental Disorders | 1.1 | 0.919 – 1.31 | 0.309 | 138 | 1339 | all | phecode |
| 295.2 | Paranoid disorders | Mental Disorders | 1.01 | 0.827 – 1.22 | 0.956 | 118 | 1079 | all | phecode |
| 295.3 | Psychosis | Mental Disorders | 1.06 | 0.982 – 1.15 | 0.136 | 716 | 6694 | all | phecode |
| 296 | Mood disorders | Mental Disorders | 1.05 | 1.03 – 1.08 | 2.81e-06 | 15356 | 20858 | all | phecode |
| 296.1 | Bipolar | Mental Disorders | 1.03 | 0.975 – 1.1 | 0.256 | 1301 | 11264 | all | phecode |
| 296.2 | Depression | Mental Disorders | 1.05 | 1.03 – 1.08 | 3.51e-06 | 14833 | 20856 | all | phecode |
| 296.22 | Major depressive disorder | Mental Disorders | 1.06 | 1.03 – 1.08 | 1.12e-06 | 13850 | 20853 | all | phecode |
| 297 | Suicidal ideation or attempt | Mental Disorders | 1.1 | 1.03 – 1.18 | 0.00544 | 985 | 9050 | all | phecode |
| 297.1 | Suicidal ideation | Mental Disorders | 1.12 | 1.04 – 1.21 | 0.00279 | 788 | 7310 | all | phecode |
| 297.2 | Suicide or self-inflicted injury | Mental Disorders | 1.13 | 1 – 1.29 | 0.0499 | 285 | 2654 | all | phecode |
| 300 | Anxiety disorders | Mental Disorders | 1.05 | 1.03 – 1.07 | 1.28e-05 | 15419 | 20850 | all | phecode |
| 300.1 | Anxiety disorder | Mental Disorders | 1.05 | 1.03 – 1.07 | 3.29e-05 | 14517 | 20855 | all | phecode |
| 300.11 | Generalized anxiety disorder | Mental Disorders | 1.03 | 1 – 1.06 | 0.0464 | 5546 | 20512 | all | phecode |
| 300.12 | Agorophobia, social phobia, and panic disorder | Mental Disorders | 1.08 | 1.02 – 1.15 | 0.0102 | 1360 | 11377 | all | phecode |
| 300.13 | Phobia | Mental Disorders | 1.04 | 0.975 – 1.11 | 0.22 | 1051 | 9542 | all | phecode |
| 300.3 | Obsessive-compulsive disorders | Mental Disorders | 0.994 | 0.885 – 1.12 | 0.925 | 328 | 3018 | all | phecode |
| 300.4 | Dysthymic disorder | Mental Disorders | 1.06 | 1.01 – 1.1 | 0.014 | 2420 | 16552 | all | phecode |
| 300.8 | Acute reaction to stress | Mental Disorders | 1.09 | 0.989 – 1.19 | 0.0837 | 504 | 4825 | all | phecode |
| 300.9 | Posttraumatic stress disorder | Mental Disorders | 1.04 | 0.964 – 1.12 | 0.321 | 843 | 7909 | all | phecode |
| 301 | Personality disorders | Mental Disorders | 1.07 | 0.968 – 1.18 | 0.187 | 477 | 4539 | all | phecode |
| 301.2 | Antisocial/borderline personality disorder | Mental Disorders | 0.975 | 0.852 – 1.11 | 0.708 | 254 | 2393 | all | phecode |
| 302 | Sexual and gender identity disorders | Mental Disorders | 0.996 | 0.959 – 1.03 | 0.85 | 3700 | 13808 | all | phecode |
| 302.1 | Decreased libido | Mental Disorders | 0.93 | 0.842 – 1.03 | 0.148 | 447 | 4331 | all | phecode |
| 303 | Psychogenic and somatoform disorders | Mental Disorders | 0.996 | 0.968 – 1.02 | 0.794 | 6808 | 20043 | all | phecode |
| 303.1 | Dissociative disorder | Mental Disorders | 0.928 | 0.79 – 1.09 | 0.364 | 161 | 1573 | all | phecode |
| 303.3 | Psychogenic disorder | Mental Disorders | 0.997 | 0.968 – 1.03 | 0.813 | 6487 | 19888 | all | phecode |
| 303.31 |
Gastrointestinal malfunction arising fromGastrointestinal malfunction arising from mental factors
|
Mental Disorders | 0.93 | 0.844 – 1.03 | 0.146 | 471 | 4623 | all | phecode |
| 303.4 | Somatoform disorder | Mental Disorders | 0.979 | 0.921 – 1.04 | 0.486 | 1177 | 11180 | all | phecode |
| 304 | Adjustment reaction | Mental Disorders | 1.03 | 0.998 – 1.07 | 0.0678 | 3888 | 20475 | all | phecode |
| 305.2 | Eating disorder | Mental Disorders | 1.09 | 1.01 – 1.17 | 0.0193 | 901 | 8329 | all | phecode |
| 306 | Other mental disorder | Mental Disorders | 1.02 | 0.974 – 1.08 | 0.351 | 1815 | 14133 | all | phecode |
| 306.1 | Mental disorders durring/after pregnancy | Mental Disorders | 1.12 | 1.03 – 1.23 | 0.0128 | 587 | 3527 | all | phecode |
| 306.9 | Tension headache | Mental Disorders | 0.995 | 0.922 – 1.07 | 0.907 | 753 | 7277 | all | phecode |
| 312 | Conduct disorders | Mental Disorders | 1.25 | 1.1 – 1.43 | 0.000769 | 254 | 2501 | all | phecode |
| 312.3 | Impulse control disorder | Mental Disorders | 1.19 | 0.938 – 1.52 | 0.151 | 74 | 736 | all | phecode |
| 313 | Pervasive developmental disorders | Mental Disorders | 1.11 | 1.05 – 1.17 | 8.98e-05 | 1571 | 14633 | all | phecode |
| 313.1 | Attention deficit hyperactivity disorder | Mental Disorders | 1.13 | 1.07 – 1.2 | 1.97e-05 | 1392 | 13190 | all | phecode |
| 313.2 | Tics and stuttering | Mental Disorders | 0.981 | 0.773 – 1.25 | 0.874 | 77 | 770 | all | phecode |
| 313.3 | Autism | Mental Disorders | 0.915 | 0.709 – 1.18 | 0.494 | 64 | 621 | all | phecode |
| 315 | Develomental delays and disorders | Mental Disorders | 1.06 | 0.977 – 1.15 | 0.163 | 684 | 6788 | all | phecode |
| 315.1 | Learning disorder | Mental Disorders | 0.905 | 0.726 – 1.13 | 0.374 | 87 | 860 | all | phecode |
| 315.2 | Speech and language disorder | Mental Disorders | 0.996 | 0.876 – 1.13 | 0.952 | 254 | 2539 | all | phecode |
| 316 | Substance addiction and disorders | Mental Disorders | 1.11 | 1.08 – 1.15 | 1.36e-09 | 3682 | 32680 | all | phecode |
| 316.1 | Polyneuropathy due to drugs | Mental Disorders | 0.98 | 0.902 – 1.06 | 0.634 | 634 | 6331 | all | phecode |
| 317 | Alcohol-related disorders | Mental Disorders | 1.15 | 1.1 – 1.2 | 3.7e-11 | 2525 | 22920 | all | phecode |
| 317.1 | Alcoholism | Mental Disorders | 1.17 | 1.12 – 1.23 | 5.1e-11 | 1986 | 19339 | all | phecode |
| 317.11 | Alcoholic liver damage | Mental Disorders | 1.1 | 0.99 – 1.22 | 0.077 | 408 | 4080 | all | phecode |
| 318 | Tobacco use disorder | Mental Disorders | 1.18 | 1.15 – 1.21 | 4.22e-40 | 8622 | 34842 | all | phecode |
| 320 | Meningitis | Neurological | 0.99 | 0.89 – 1.1 | 0.86 | 382 | 3820 | all | phecode |
| 323 | Encephalitis | Neurological | 1.06 | 0.912 – 1.23 | 0.44 | 181 | 1809 | all | phecode |
| 323.8 | Encephalitis, non-infectious | Neurological | 1.03 | 0.869 – 1.21 | 0.757 | 153 | 1527 | all | phecode |
| 324 | Other CNS infection and poliomyelitis | Neurological | 1.15 | 1.01 – 1.3 | 0.0293 | 288 | 2880 | all | phecode |
| 325 |
Phlebitis and thrombophlebitis of intracranialPhlebitis and thrombophlebitis of intracranial venous sinuses
|
Neurological | 1.13 | 0.852 – 1.49 | 0.403 | 53 | 530 | all | phecode |
| 327 | Sleep disorders | Neurological | 1.01 | 0.993 – 1.03 | 0.197 | 14941 | 31602 | all | phecode |
| 327.1 | Hypersomnia | Neurological | 0.975 | 0.932 – 1.02 | 0.29 | 2061 | 19110 | all | phecode |
| 327.3 | Sleep apnea | Neurological | 1 | 0.982 – 1.03 | 0.711 | 10909 | 31304 | all | phecode |
| 327.31 | Central/nonobstroctive sleep apnea | Neurological | 1.03 | 0.936 – 1.13 | 0.575 | 492 | 4784 | all | phecode |
| 327.32 | Obstructive sleep apnea | Neurological | 0.999 | 0.975 – 1.02 | 0.942 | 8744 | 30530 | all | phecode |
| 327.4 | Insomnia | Neurological | 1.03 | 1 – 1.06 | 0.041 | 5524 | 30960 | all | phecode |
| 327.41 | Organic or persistent insomnia | Neurological | 1.01 | 0.949 – 1.07 | 0.834 | 1265 | 12120 | all | phecode |
| 327.5 | Parasomnia | Neurological | 0.966 | 0.889 – 1.05 | 0.42 | 604 | 5913 | all | phecode |
| 327.6 | Circadian rhythm sleep disorder | Neurological | 1.07 | 0.945 – 1.21 | 0.285 | 274 | 2666 | all | phecode |
| 327.7 | Sleep related movement disorders | Neurological | 1.04 | 0.995 – 1.1 | 0.0802 | 1786 | 17323 | all | phecode |
| 327.71 | Restless legs syndrome | Neurological | 1.05 | 0.999 – 1.11 | 0.0538 | 1570 | 15360 | all | phecode |
| 327.72 | Sleep related leg cramps | Neurological | 1.01 | 0.81 – 1.27 | 0.909 | 83 | 822 | all | phecode |
| 331 | Other cerebral degenerations | Neurological | 0.988 | 0.915 – 1.07 | 0.754 | 717 | 7024 | all | phecode |
| 331.1 | Hydrocephalus | Neurological | 0.969 | 0.857 – 1.1 | 0.619 | 284 | 2836 | all | phecode |
| 331.9 | Cerebral degeneration, unspecified | Neurological | 0.996 | 0.902 – 1.1 | 0.931 | 419 | 4026 | all | phecode |
| 332 | Parkinson's disease | Neurological | 0.969 | 0.875 – 1.07 | 0.538 | 415 | 4128 | all | phecode |
| 333 |
Extrapyramidal disease and abnormal movementExtrapyramidal disease and abnormal movement disorders
|
Neurological | 1 | 0.963 – 1.04 | 0.935 | 2868 | 26583 | all | phecode |
| 333.1 | Essential tremor | Neurological | 0.983 | 0.911 – 1.06 | 0.666 | 725 | 7163 | all | phecode |
| 333.2 | Myoclonus | Neurological | 0.948 | 0.804 – 1.12 | 0.526 | 159 | 1590 | all | phecode |
| 333.4 | Torsion dystonia | Neurological | 0.935 | 0.839 – 1.04 | 0.23 | 352 | 3504 | all | phecode |
| 333.8 | Other degenerative diseases of the basal ganglia | Neurological | 1 | 0.807 – 1.25 | 0.972 | 89 | 890 | all | phecode |
| 334 | Degenerative disease of the spinal cord | Neurological | 1.03 | 0.968 – 1.1 | 0.338 | 1058 | 10562 | all | phecode |
| 334.1 | Spinocerebellar disease | Neurological | 0.829 | 0.656 – 1.05 | 0.116 | 79 | 790 | all | phecode |
| 334.2 | Anterior horn cell disease | Neurological | 1 | 0.826 – 1.22 | 0.986 | 110 | 1080 | all | phecode |
| 334.21 | Amyotrophic Lateral Sclerosis | Neurological | 0.924 | 0.733 – 1.16 | 0.502 | 71 | 693 | all | phecode |
| 335 | Multiple sclerosis | Neurological | 1.02 | 0.917 – 1.13 | 0.756 | 396 | 3951 | all | phecode |
| 337 | Disorders of the autonomic nervous system | Neurological | 1.01 | 0.942 – 1.09 | 0.704 | 808 | 7413 | all | phecode |
| 337.1 | Peripheral autonomic neuropathy | Neurological | 1.06 | 0.949 – 1.18 | 0.31 | 370 | 3164 | all | phecode |
| 338 | Pain | Neurological | 1.03 | 1.01 – 1.05 | 0.00566 | 20346 | 26417 | all | phecode |
| 338.1 | Acute pain | Neurological | 1.03 | 1.01 – 1.05 | 0.0129 | 15582 | 26313 | all | phecode |
| 338.2 | Chronic pain | Neurological | 1.03 | 1.01 – 1.06 | 0.00389 | 10994 | 26368 | all | phecode |
| 339 | Other headache syndromes | Neurological | 1.01 | 0.982 – 1.03 | 0.632 | 9242 | 34658 | all | phecode |
| 340 | Migraine | Neurological | 1 | 0.977 – 1.03 | 0.765 | 6708 | 30587 | all | phecode |
| 340.1 | Migrain with aura | Neurological | 1 | 0.966 – 1.04 | 0.96 | 3624 | 23684 | all | phecode |
| 341 |
Other demyelinating diseases of central nervousOther demyelinating diseases of central nervous system
|
Neurological | 1 | 0.842 – 1.19 | 0.984 | 133 | 1330 | all | phecode |
| 342 | Hemiplegia | Neurological | 0.952 | 0.866 – 1.05 | 0.303 | 464 | 4607 | all | phecode |
| 343 | Infantile cerebral palsy | Neurological | 1.14 | 0.911 – 1.43 | 0.247 | 85 | 847 | all | phecode |
| 344 | Other paralytic syndromes | Neurological | 1.11 | 1.02 – 1.2 | 0.0103 | 682 | 6808 | all | phecode |
| 345 | Epilepsy, recurrent seizures, convulsions | Neurological | 0.995 | 0.955 – 1.04 | 0.816 | 2553 | 25307 | all | phecode |
| 345.1 | Epilepsy | Neurological | 1.02 | 0.947 – 1.1 | 0.589 | 747 | 7465 | all | phecode |
| 345.11 | Generalized convulsive epilepsy | Neurological | 1.05 | 0.921 – 1.21 | 0.444 | 233 | 2330 | all | phecode |
| 345.12 | Partial epilepsy | Neurological | 1.04 | 0.952 – 1.14 | 0.381 | 534 | 5335 | all | phecode |
| 345.3 | Convulsions | Neurological | 1 | 0.958 – 1.04 | 1 | 2396 | 23796 | all | phecode |
| 346 |
Abnormal findings on study of brain and/orAbnormal findings on study of brain and/or nervous system
|
Neurological | 0.949 | 0.814 – 1.11 | 0.506 | 183 | 1824 | all | phecode |
| 346.1 |
Nonspecific abnormal findings on radiologicalNonspecific abnormal findings on radiological and other examination of skull and head
|
Neurological | 0.987 | 0.935 – 1.04 | 0.629 | 1472 | 14587 | all | phecode |
| 346.2 |
Nonspecific abnormal results of function studyNonspecific abnormal results of function study of brain and central nervous system
|
Neurological | 0.881 | 0.729 – 1.07 | 0.191 | 120 | 1181 | all | phecode |
| 346.3 |
Nonspecific abnormal findings in cerebrospinalNonspecific abnormal findings in cerebrospinal fluid
|
Neurological | 0.944 | 0.78 – 1.14 | 0.552 | 110 | 1100 | all | phecode |
| 347 | Cataplexy and narcolepsy | Neurological | 0.982 | 0.797 – 1.21 | 0.866 | 101 | 1010 | all | phecode |
| 348 | Other conditions of brain | Neurological | 0.993 | 0.946 – 1.04 | 0.788 | 1793 | 17894 | all | phecode |
| 348.2 | Cerebral edema and compression of brain | Neurological | 0.993 | 0.927 – 1.06 | 0.846 | 905 | 9034 | all | phecode |
| 348.4 | Cerebral cysts | Neurological | 0.848 | 0.738 – 0.974 | 0.0193 | 229 | 2290 | all | phecode |
| 348.7 | Coma | Neurological | 1.04 | 0.901 – 1.19 | 0.614 | 229 | 2275 | all | phecode |
| 348.8 | Encephalopathy, not elsewhere classified | Neurological | 1.01 | 0.943 – 1.08 | 0.75 | 853 | 8479 | all | phecode |
| 348.9 | Other conditions of brain, NOS | Neurological | 1 | 0.961 – 1.05 | 0.884 | 2341 | 23287 | all | phecode |
| 349 |
Other and unspecified disorders of the nervousOther and unspecified disorders of the nervous system
|
Neurological | 0.987 | 0.922 – 1.06 | 0.703 | 941 | 9385 | all | phecode |
| 350 | Abnormal movement | Neurological | 1 | 0.975 – 1.03 | 0.927 | 6706 | 38762 | all | phecode |
| 350.1 | Abnormal involuntary movements | Neurological | 0.995 | 0.959 – 1.03 | 0.799 | 3273 | 30524 | all | phecode |
| 350.2 | Abnormality of gait | Neurological | 1.01 | 0.981 – 1.05 | 0.408 | 3920 | 30520 | all | phecode |
| 350.3 | Lack of coordination | Neurological | 0.976 | 0.916 – 1.04 | 0.45 | 1062 | 10554 | all | phecode |
| 350.5 | Abnormal reflex | Neurological | 1.08 | 0.935 – 1.25 | 0.292 | 200 | 1988 | all | phecode |
| 350.6 | Disturbances of sensation of smell and taste | Neurological | 0.939 | 0.86 – 1.03 | 0.162 | 558 | 5576 | all | phecode |
| 351 | Other peripheral nerve disorders | Neurological | 1.01 | 0.983 – 1.04 | 0.501 | 7401 | 34460 | all | phecode |
| 352 | Disorders of other cranial nerves | Neurological | 0.998 | 0.949 – 1.05 | 0.941 | 1714 | 17106 | all | phecode |
| 352.1 | Trigeminal nerve disorders [CN5] | Neurological | 0.968 | 0.887 – 1.06 | 0.473 | 535 | 5344 | all | phecode |
| 352.2 | Facial nerve disorders [CN7] | Neurological | 1.02 | 0.951 – 1.1 | 0.538 | 783 | 7826 | all | phecode |
| 353 | Nerve root and plexus disorders | Neurological | 1.02 | 0.989 – 1.06 | 0.196 | 4256 | 33369 | all | phecode |
| 353.1 | Nerve plexus lesions | Neurological | 1.04 | 0.934 – 1.15 | 0.483 | 390 | 3900 | all | phecode |
| 353.2 | Nerve root lesions | Neurological | 1.01 | 0.846 – 1.2 | 0.936 | 130 | 1287 | all | phecode |
| 355 | Complex regional/central pain syndrome | Neurological | 1.04 | 0.947 – 1.13 | 0.441 | 531 | 5295 | all | phecode |
| 355.1 | Chronic pain syndrome | Neurological | 1.03 | 0.961 – 1.11 | 0.376 | 843 | 8386 | all | phecode |
| 356 | Hereditary and idiopathic peripheral neuropathy | Neurological | 1.03 | 0.989 – 1.08 | 0.148 | 2335 | 20731 | all | phecode |
| 357 | Inflammatory and toxic neuropathy | Neurological | 0.996 | 0.961 – 1.03 | 0.843 | 3472 | 29956 | all | phecode |
| 358 | Myoneural disorders | Neurological | 1.04 | 0.973 – 1.1 | 0.268 | 1147 | 11391 | all | phecode |
| 358.1 | Myasthenia gravis | Neurological | 1.03 | 0.846 – 1.25 | 0.766 | 109 | 1082 | all | phecode |
| 359 | Muscular dystrophies and other myopathies | Neurological | 1.02 | 0.962 – 1.09 | 0.465 | 1134 | 11274 | all | phecode |
| 359.1 | Muscular dystrophies | Neurological | 1.09 | 0.85 – 1.41 | 0.487 | 64 | 632 | all | phecode |
| 359.2 | Myopathy | Neurological | 1.01 | 0.945 – 1.07 | 0.847 | 1092 | 10843 | all | phecode |
| 360 | Disorders of the globe | Sense Organs | 0.963 | 0.801 – 1.16 | 0.692 | 131 | 1276 | all | phecode |
| 360.2 | Progressive myopia | Sense Organs | 0.985 | 0.754 – 1.29 | 0.91 | 65 | 640 | all | phecode |
| 361 | Retinal detachments and defects | Sense Organs | 0.976 | 0.903 – 1.05 | 0.538 | 733 | 7131 | all | phecode |
| 361.1 | Retinal detachment with retinal defect | Sense Organs | 1.01 | 0.898 – 1.14 | 0.836 | 302 | 2962 | all | phecode |
| 362 | Other retinal disorders | Sense Organs | 0.986 | 0.951 – 1.02 | 0.447 | 3569 | 22997 | all | phecode |
| 362.2 |
Degeneration of macula and posterior pole ofDegeneration of macula and posterior pole of retina
|
Sense Organs | 0.978 | 0.935 – 1.02 | 0.351 | 2172 | 15483 | all | phecode |
| 362.21 | Macular degeneration, dry | Sense Organs | 0.999 | 0.902 – 1.1 | 0.977 | 419 | 3438 | all | phecode |
| 362.22 | Macular degeneration, wet | Sense Organs | 1.21 | 1.02 – 1.44 | 0.031 | 148 | 1184 | all | phecode |
| 362.23 | Cystoid macular degeneration of retina | Sense Organs | 0.976 | 0.881 – 1.08 | 0.647 | 408 | 3839 | all | phecode |
| 362.26 | Macular puckering of retina | Sense Organs | 0.968 | 0.905 – 1.03 | 0.339 | 976 | 8610 | all | phecode |
| 362.27 | Drusen (degenerative) of retina | Sense Organs | 1.04 | 0.946 – 1.14 | 0.428 | 488 | 4558 | all | phecode |
| 362.29 | Macular degeneration (senile) of retina NOS | Sense Organs | 0.972 | 0.926 – 1.02 | 0.262 | 1883 | 13955 | all | phecode |
| 362.3 | Other nondiabetic retinopathy | Sense Organs | 1.02 | 0.954 – 1.09 | 0.56 | 976 | 8527 | all | phecode |
| 362.31 | Separation of retinal layers | Sense Organs | 1.06 | 0.955 – 1.18 | 0.273 | 413 | 4056 | all | phecode |
| 362.4 | Retinal vascular changes and abnomalities | Sense Organs | 1.02 | 0.943 – 1.11 | 0.58 | 662 | 5933 | all | phecode |
| 362.6 | Peripheral retinal degenerations | Sense Organs | 1.02 | 0.918 – 1.13 | 0.713 | 392 | 3787 | all | phecode |
| 362.7 | Hereditary retinal dystrophies | Sense Organs | 0.989 | 0.859 – 1.14 | 0.873 | 215 | 2103 | all | phecode |
| 362.8 | Retinal hemorrhage/ischemia | Sense Organs | 1.04 | 0.915 – 1.19 | 0.52 | 241 | 2368 | all | phecode |
| 362.9 | Retinal edema | Sense Organs | 0.947 | 0.845 – 1.06 | 0.349 | 324 | 2936 | all | phecode |
| 363 |
Chorioretinal inflammations, scars, and otherChorioretinal inflammations, scars, and other disorders of choroid
|
Sense Organs | 1.03 | 0.938 – 1.13 | 0.534 | 492 | 4746 | all | phecode |
| 363.3 | Chorioretinal scars | Sense Organs | 1.1 | 0.984 – 1.24 | 0.0911 | 332 | 3184 | all | phecode |
| 364 | Corneal opacity and other disorders of cornea | Sense Organs | 1.05 | 0.987 – 1.12 | 0.125 | 1132 | 10772 | all | phecode |
| 364.1 | Corneal opacity | Sense Organs | 0.958 | 0.864 – 1.06 | 0.408 | 394 | 3846 | all | phecode |
| 364.2 | Corneal edema | Sense Organs | 0.938 | 0.777 – 1.13 | 0.503 | 123 | 1208 | all | phecode |
| 364.4 | Corneal degenerations | Sense Organs | 1.06 | 0.953 – 1.17 | 0.297 | 402 | 3962 | all | phecode |
| 364.41 | Keratoconus | Sense Organs | 0.838 | 0.654 – 1.07 | 0.161 | 75 | 739 | all | phecode |
| 364.5 | Corneal dystrophy | Sense Organs | 1.04 | 0.948 – 1.14 | 0.393 | 502 | 4682 | all | phecode |
| 364.51 | Fuchs' dystrophy | Sense Organs | 1.04 | 0.911 – 1.18 | 0.581 | 266 | 2521 | all | phecode |
| 364.9 | Cornea replaced by transplant | Sense Organs | 1.03 | 0.835 – 1.26 | 0.799 | 91 | 885 | all | phecode |
| 365 | Glaucoma | Sense Organs | 0.978 | 0.939 – 1.02 | 0.282 | 2672 | 21326 | all | phecode |
| 365.1 | Open-angle glaucoma | Sense Organs | 0.984 | 0.91 – 1.06 | 0.683 | 705 | 6491 | all | phecode |
| 365.11 | Primary open angle glaucoma | Sense Organs | 1.03 | 0.929 – 1.14 | 0.586 | 403 | 3681 | all | phecode |
| 365.2 | Primary angle-closure glaucoma | Sense Organs | 1.05 | 0.924 – 1.2 | 0.432 | 251 | 2370 | all | phecode |
| 366 | Cataract | Sense Organs | 0.994 | 0.968 – 1.02 | 0.65 | 8611 | 28043 | all | phecode |
| 366.1 | Nonsenile Cataract | Sense Organs | 1.01 | 0.877 – 1.17 | 0.869 | 207 | 1979 | all | phecode |
| 366.2 | Senile cataract | Sense Organs | 1.01 | 0.978 – 1.04 | 0.565 | 5480 | 24980 | all | phecode |
| 367 |
Disorders of refraction and accommodationDisorders of refraction and accommodation; blindness and low vision
|
Sense Organs | 1.01 | 0.984 – 1.03 | 0.517 | 8967 | 37779 | all | phecode |
| 367.1 | Myopia | Sense Organs | 0.999 | 0.969 – 1.03 | 0.94 | 5014 | 34677 | all | phecode |
| 367.2 | Astigmatism | Sense Organs | 1.01 | 0.978 – 1.04 | 0.535 | 4161 | 32463 | all | phecode |
| 367.8 | Hypermetropia | Sense Organs | 1.01 | 0.968 – 1.06 | 0.564 | 2039 | 18599 | all | phecode |
| 367.9 | Blindness and low vision | Sense Organs | 1.02 | 0.966 – 1.08 | 0.437 | 1277 | 12356 | all | phecode |
| 368 | Visual disturbances | Sense Organs | 1.01 | 0.983 – 1.04 | 0.443 | 5715 | 39599 | all | phecode |
| 368.1 | Amblyopia | Sense Organs | 1.08 | 0.999 – 1.18 | 0.0541 | 651 | 6479 | all | phecode |
| 368.2 | Diplopia and disorders of binocular vision | Sense Organs | 1 | 0.94 – 1.07 | 0.977 | 1087 | 10786 | all | phecode |
| 368.3 | Anisometropia | Sense Organs | 1.04 | 0.899 – 1.2 | 0.617 | 219 | 2168 | all | phecode |
| 368.4 | Visual field defects | Sense Organs | 0.973 | 0.914 – 1.03 | 0.376 | 1132 | 11173 | all | phecode |
| 368.9 | Subjective visual disturbances | Sense Organs | 0.963 | 0.904 – 1.03 | 0.252 | 1070 | 10620 | all | phecode |
| 368.91 | Psychophysical visual disturbances | Sense Organs | 1.03 | 0.857 – 1.25 | 0.728 | 120 | 1171 | all | phecode |
| 369 | Infection of the eye | Sense Organs | 1 | 0.965 – 1.04 | 0.932 | 3185 | 28240 | all | phecode |
| 369.2 | Eye infection, viral | Sense Organs | 0.996 | 0.908 – 1.09 | 0.928 | 502 | 4954 | all | phecode |
| 369.5 | Conjunctivitis, infectious | Sense Organs | 1 | 0.96 – 1.04 | 0.991 | 2716 | 24970 | all | phecode |
| 370 | Keratitis | Sense Organs | 0.973 | 0.92 – 1.03 | 0.342 | 1365 | 13169 | all | phecode |
| 370.1 | Corneal ulcer | Sense Organs | 1.03 | 0.897 – 1.19 | 0.664 | 223 | 2194 | all | phecode |
| 370.2 | Superficial keratitis | Sense Organs | 1 | 0.916 – 1.09 | 0.991 | 546 | 5393 | all | phecode |
| 370.3 | Keratoconjunctivitis | Sense Organs | 1 | 0.925 – 1.09 | 0.923 | 649 | 6263 | all | phecode |
| 370.31 | Keratoconjunctivitis sicca | Sense Organs | 0.954 | 0.819 – 1.11 | 0.545 | 179 | 1677 | all | phecode |
| 371 | Inflammation of the eye | Sense Organs | 1.01 | 0.979 – 1.04 | 0.487 | 4414 | 32310 | all | phecode |
| 371.1 | Uveitis, noninfectious or NOS | Sense Organs | 1.06 | 0.969 – 1.16 | 0.197 | 541 | 5278 | all | phecode |
| 371.2 | Conjunctivitis, noninfectious | Sense Organs | 1.04 | 0.971 – 1.12 | 0.255 | 906 | 8939 | all | phecode |
| 371.21 | Allergic conjunctivitis | Sense Organs | 1.04 | 0.964 – 1.12 | 0.321 | 756 | 7515 | all | phecode |
| 371.3 | Inflammation of eyelids | Sense Organs | 1.01 | 0.97 – 1.04 | 0.756 | 3398 | 26983 | all | phecode |
| 371.33 | Noninfectious dermatoses of eyelid | Sense Organs | 1.11 | 0.932 – 1.33 | 0.236 | 133 | 1291 | all | phecode |
| 372 | Disorders of conjunctiva | Sense Organs | 0.984 | 0.925 – 1.05 | 0.62 | 1118 | 10728 | all | phecode |
| 374 | Other disorders of eyelids | Sense Organs | 0.989 | 0.951 – 1.03 | 0.583 | 2940 | 24188 | all | phecode |
| 374.1 | Ectropion or entropion | Sense Organs | 1.05 | 0.949 – 1.16 | 0.36 | 431 | 4084 | all | phecode |
| 374.2 | Lagophthalmos | Sense Organs | 0.994 | 0.872 – 1.13 | 0.926 | 235 | 2335 | all | phecode |
| 374.3 | Ptosis of eyelid | Sense Organs | 0.993 | 0.932 – 1.06 | 0.815 | 1102 | 10734 | all | phecode |
| 374.6 | Dermatochalasis | Sense Organs | 1.01 | 0.947 – 1.08 | 0.771 | 1040 | 9720 | all | phecode |
| 375 | Disorders of lacrimal system | Sense Organs | 0.999 | 0.964 – 1.04 | 0.959 | 3694 | 26045 | all | phecode |
| 375.1 | Dry eyes | Sense Organs | 1.02 | 0.982 – 1.05 | 0.349 | 4040 | 26751 | all | phecode |
| 375.2 | Epiphora | Sense Organs | 1.11 | 1.01 – 1.23 | 0.0349 | 442 | 4354 | all | phecode |
| 376 | Disorders of the orbit | Sense Organs | 1.02 | 0.909 – 1.13 | 0.787 | 352 | 3508 | all | phecode |
| 377 | Disorders of optic nerve and visual pathways | Sense Organs | 1.01 | 0.94 – 1.08 | 0.855 | 913 | 9021 | all | phecode |
| 377.1 | Optic atrophy | Sense Organs | 1.06 | 0.937 – 1.2 | 0.354 | 283 | 2793 | all | phecode |
| 377.3 | Optic neuritis/neuropathy | Sense Organs | 1.02 | 0.936 – 1.11 | 0.67 | 585 | 5775 | all | phecode |
| 378 |
Strabismus and other disorders of binocular eyeStrabismus and other disorders of binocular eye movements
|
Sense Organs | 1.05 | 0.988 – 1.11 | 0.118 | 1275 | 12460 | all | phecode |
| 378.1 | Strabismus (not specified as paralytic) | Sense Organs | 1.1 | 1.02 – 1.18 | 0.0118 | 828 | 8130 | all | phecode |
| 378.2 | Nystagmus and other irregular eye movements | Sense Organs | 0.877 | 0.743 – 1.04 | 0.122 | 170 | 1686 | all | phecode |
| 378.5 | Paralytic strabismus | Sense Organs | 1.01 | 0.908 – 1.13 | 0.794 | 349 | 3437 | all | phecode |
| 379 | Other disorders of eye | Sense Organs | 0.99 | 0.96 – 1.02 | 0.53 | 5046 | 29999 | all | phecode |
| 379.1 | Scleritis and episcleritis | Sense Organs | 0.939 | 0.805 – 1.1 | 0.429 | 176 | 1743 | all | phecode |
| 379.2 | Disorders of vitreous body | Sense Organs | 0.981 | 0.947 – 1.02 | 0.307 | 3634 | 23186 | all | phecode |
| 379.3 | Aphakia and other disorders of lens | Sense Organs | 1.02 | 0.856 – 1.22 | 0.81 | 135 | 1258 | all | phecode |
| 379.4 | Anomalies of pupillary function | Sense Organs | 1.01 | 0.894 – 1.14 | 0.87 | 287 | 2833 | all | phecode |
| 379.5 | Disorders of iris and ciliary body | Sense Organs | 0.982 | 0.871 – 1.11 | 0.774 | 304 | 2948 | all | phecode |
| 379.51 | Pigmentary iris degeneration | Sense Organs | 1.16 | 0.914 – 1.47 | 0.222 | 77 | 731 | all | phecode |
| 379.9 | Pain, swelling or discharge of eye | Sense Organs | 0.93 | 0.874 – 0.989 | 0.0212 | 1129 | 11130 | all | phecode |
| 380 | Disorders of external ear | Sense Organs | 0.964 | 0.922 – 1.01 | 0.103 | 2242 | 20393 | all | phecode |
| 380.1 | Otitis externa | Sense Organs | 1.06 | 1 – 1.12 | 0.0449 | 1469 | 14580 | all | phecode |
| 380.4 | Impacted cerumen | Sense Organs | 0.965 | 0.927 – 1.01 | 0.0867 | 2648 | 23557 | all | phecode |
| 381 | Otitis media and Eustachian tube disorders | Sense Organs | 0.993 | 0.961 – 1.03 | 0.669 | 4255 | 36417 | all | phecode |
| 381.1 | Otitis media | Sense Organs | 0.994 | 0.957 – 1.03 | 0.755 | 3079 | 29813 | all | phecode |
| 381.11 | Suppurative and unspecified otitis media | Sense Organs | 0.99 | 0.95 – 1.03 | 0.62 | 2610 | 25602 | all | phecode |
| 381.2 | Eustachian tube disorders | Sense Organs | 0.974 | 0.927 – 1.02 | 0.289 | 1816 | 17827 | all | phecode |
| 381.3 | Mastoiditis & related conditions | Sense Organs | 0.839 | 0.711 – 0.99 | 0.0375 | 153 | 1530 | all | phecode |
| 381.9 | Otorrhea | Sense Organs | 1.07 | 0.961 – 1.19 | 0.217 | 372 | 3713 | all | phecode |
| 382 | Otalgia | Sense Organs | 1.03 | 0.981 – 1.08 | 0.239 | 1884 | 18673 | all | phecode |
| 383 | Otosclerosis | Sense Organs | 0.925 | 0.771 – 1.11 | 0.403 | 124 | 1240 | all | phecode |
| 384 | Other disorders of tympanic membrane | Sense Organs | 1.07 | 0.975 – 1.17 | 0.157 | 516 | 5156 | all | phecode |
| 384.1 | Myringitis | Sense Organs | 1 | 0.748 – 1.34 | 0.984 | 51 | 502 | all | phecode |
| 384.4 | Perforation of tympanic membrane | Sense Organs | 1.09 | 0.987 – 1.21 | 0.0883 | 403 | 4029 | all | phecode |
| 385 | Other disorders of middle ear and mastoid | Sense Organs | 0.996 | 0.901 – 1.1 | 0.931 | 432 | 4320 | all | phecode |
| 385.3 | Cholesteatoma | Sense Organs | 0.934 | 0.825 – 1.06 | 0.286 | 277 | 2770 | all | phecode |
| 385.5 |
Tympanosclerosis and middle ear disease relatedTympanosclerosis and middle ear disease related to otitis media
|
Sense Organs | 0.951 | 0.785 – 1.15 | 0.605 | 118 | 1180 | all | phecode |
| 386 |
Vertiginous syndromes and other disorders ofVertiginous syndromes and other disorders of vestibular system
|
Sense Organs | 1.02 | 0.975 – 1.07 | 0.356 | 1882 | 18186 | all | phecode |
| 386.1 | Meniere's disease | Sense Organs | 1.05 | 0.934 – 1.18 | 0.418 | 319 | 3156 | all | phecode |
| 386.2 | Peripheral or central vertigo | Sense Organs | 1.02 | 0.971 – 1.08 | 0.383 | 1586 | 15423 | all | phecode |
| 386.21 | Central origin vertigo | Sense Organs | 1 | 0.946 – 1.07 | 0.885 | 1208 | 11844 | all | phecode |
| 386.3 | Labyrinthitis | Sense Organs | 1 | 0.948 – 1.06 | 0.958 | 1482 | 14530 | all | phecode |
| 386.9 |
Dizziness and giddiness (Light-headedness andDizziness and giddiness (Light-headedness and vertigo)
|
Sense Organs | 0.99 | 0.964 – 1.02 | 0.431 | 6933 | 38286 | all | phecode |
| 388 | Other disorders of ear | Sense Organs | 0.991 | 0.927 – 1.06 | 0.797 | 960 | 9501 | all | phecode |
| 389 | Hearing loss | Sense Organs | 0.995 | 0.971 – 1.02 | 0.688 | 8182 | 38069 | all | phecode |
| 389.1 | Sensorineural hearing loss | Sense Organs | 0.999 | 0.967 – 1.03 | 0.969 | 4107 | 29258 | all | phecode |
| 389.2 | Conductive hearing loss | Sense Organs | 0.983 | 0.918 – 1.05 | 0.635 | 905 | 9042 | all | phecode |
| 389.3 | Degenerative and vascular disorders of ear | Sense Organs | 1.07 | 0.931 – 1.24 | 0.327 | 192 | 1808 | all | phecode |
| 389.4 | Tinnitus | Sense Organs | 0.973 | 0.932 – 1.02 | 0.222 | 2291 | 22130 | all | phecode |
| 389.5 | Disorders of acoustic nerve | Sense Organs | 1.05 | 0.873 – 1.27 | 0.586 | 124 | 1229 | all | phecode |
| 394 | Rheumatic disease of the heart valves | Circulatory System | 0.955 | 0.905 – 1.01 | 0.1 | 1458 | 13732 | all | phecode |
| 394.1 | Mitral valve stenosis and aortic valve stenosis | Circulatory System | 1 | 0.897 – 1.12 | 0.964 | 350 | 3415 | all | phecode |
| 394.2 | Mitral valve disease | Circulatory System | 0.922 | 0.837 – 1.02 | 0.101 | 462 | 4560 | all | phecode |
| 394.3 | Aortic valve disease | Circulatory System | 0.97 | 0.829 – 1.14 | 0.707 | 176 | 1691 | all | phecode |
| 394.4 | Acute rheumatic heart disease | Circulatory System | 1.2 | 0.923 – 1.57 | 0.173 | 55 | 546 | all | phecode |
| 394.7 | Disease of tricuspid valve | Circulatory System | 0.905 | 0.832 – 0.985 | 0.0211 | 587 | 5739 | all | phecode |
| 395 | Heart valve disorders | Circulatory System | 0.997 | 0.964 – 1.03 | 0.847 | 3976 | 28748 | all | phecode |
| 395.1 | Nonrheumatic mitral valve disorders | Circulatory System | 0.958 | 0.916 – 1 | 0.06 | 2175 | 20441 | all | phecode |
| 395.2 | Nonrheumatic aortic valve disorders | Circulatory System | 1.01 | 0.963 – 1.06 | 0.714 | 2060 | 17194 | all | phecode |
| 395.3 | Nonrheumatic tricuspid valve disorders | Circulatory System | 0.944 | 0.861 – 1.03 | 0.218 | 493 | 4864 | all | phecode |
| 395.4 | Nonrheumatic pulmonary valve disorders | Circulatory System | 0.804 | 0.659 – 0.98 | 0.0305 | 108 | 1080 | all | phecode |
| 395.6 | Heart valve replaced | Circulatory System | 1.01 | 0.953 – 1.08 | 0.695 | 1177 | 10833 | all | phecode |
| 396 | Abnormal heart sounds | Circulatory System | 1 | 0.973 – 1.04 | 0.815 | 4718 | 34395 | all | phecode |
| 401 | Hypertension | Circulatory System | 1.01 | 0.993 – 1.04 | 0.202 | 23317 | 23367 | all | phecode |
| 401.1 | Essential hypertension | Circulatory System | 1.01 | 0.993 – 1.04 | 0.205 | 23158 | 23364 | all | phecode |
| 401.2 | Hypertensive heart and/or renal disease | Circulatory System | 1.02 | 0.979 – 1.06 | 0.365 | 3503 | 14616 | all | phecode |
| 401.21 | Hypertensive heart disease | Circulatory System | 1.03 | 0.961 – 1.11 | 0.386 | 893 | 6607 | all | phecode |
| 401.22 | Hypertensive chronic kidney disease | Circulatory System | 1.01 | 0.97 – 1.06 | 0.52 | 2584 | 13072 | all | phecode |
| 401.3 | Other hypertensive complications | Circulatory System | 0.993 | 0.952 – 1.04 | 0.764 | 2679 | 15833 | all | phecode |
| 411 | Ischemic Heart Disease | Circulatory System | 1.03 | 1.01 – 1.06 | 0.0156 | 8807 | 30299 | all | phecode |
| 411.1 | Unstable angina (intermediate coronary syndrome) | Circulatory System | 1.06 | 0.994 – 1.14 | 0.0732 | 937 | 8574 | all | phecode |
| 411.2 | Myocardial infarction | Circulatory System | 1.04 | 1 – 1.08 | 0.0487 | 3594 | 21716 | all | phecode |
| 411.3 | Angina pectoris | Circulatory System | 1.03 | 0.983 – 1.07 | 0.24 | 2485 | 18304 | all | phecode |
| 411.4 | Coronary atherosclerosis | Circulatory System | 1.03 | 1 – 1.06 | 0.0417 | 7555 | 27492 | all | phecode |
| 411.41 | Aneurysm and dissection of heart | Circulatory System | 0.954 | 0.808 – 1.13 | 0.582 | 156 | 1529 | all | phecode |
| 411.8 |
Other chronic ischemic heart diseaseOther chronic ischemic heart disease, unspecified
|
Circulatory System | 1.02 | 0.986 – 1.05 | 0.295 | 6331 | 25741 | all | phecode |
| 411.9 |
Other acute and subacute forms of ischemicOther acute and subacute forms of ischemic heart disease
|
Circulatory System | 1.03 | 0.933 – 1.14 | 0.562 | 442 | 4211 | all | phecode |
| 414 | Other forms of chronic heart disease | Circulatory System | 0.988 | 0.951 – 1.03 | 0.537 | 3101 | 22616 | all | phecode |
| 414.2 | ASCVD | Circulatory System | 0.966 | 0.894 – 1.04 | 0.387 | 718 | 6816 | all | phecode |
| 415 | Pulmonary heart disease | Circulatory System | 0.984 | 0.949 – 1.02 | 0.386 | 3366 | 30208 | all | phecode |
| 415.1 | Acute pulmonary heart disease | Circulatory System | 1.01 | 0.967 – 1.06 | 0.557 | 1912 | 19014 | all | phecode |
| 415.11 | Pulmonary embolism and infarction, acute | Circulatory System | 1.02 | 0.968 – 1.07 | 0.525 | 1906 | 18953 | all | phecode |
| 415.2 | Chronic pulmonary heart disease | Circulatory System | 0.998 | 0.95 – 1.05 | 0.944 | 1808 | 17605 | all | phecode |
| 415.21 | Primary pulmonary hypertension | Circulatory System | 1.03 | 0.949 – 1.11 | 0.518 | 706 | 7032 | all | phecode |
| 416 | Cardiomegaly | Circulatory System | 1.05 | 0.99 – 1.11 | 0.107 | 1254 | 12372 | all | phecode |
| 418 | Nonspecific chest pain | Circulatory System | 0.996 | 0.975 – 1.02 | 0.696 | 12650 | 33952 | all | phecode |
| 418.1 | Precordial pain | Circulatory System | 1.04 | 0.984 – 1.1 | 0.165 | 1471 | 13782 | all | phecode |
| 420 | Carditis | Circulatory System | 0.973 | 0.924 – 1.03 | 0.306 | 1588 | 15680 | all | phecode |
| 420.1 | Myocarditis | Circulatory System | 1.06 | 0.861 – 1.31 | 0.565 | 97 | 958 | all | phecode |
| 420.2 | Pericarditis | Circulatory System | 0.96 | 0.894 – 1.03 | 0.268 | 842 | 8402 | all | phecode |
| 420.21 | Acute pericarditis | Circulatory System | 0.958 | 0.82 – 1.12 | 0.589 | 177 | 1764 | all | phecode |
| 420.22 | Chronic pericarditis | Circulatory System | 0.965 | 0.8 – 1.17 | 0.714 | 117 | 1153 | all | phecode |
| 420.3 | Endocarditis | Circulatory System | 0.967 | 0.897 – 1.04 | 0.374 | 764 | 7535 | all | phecode |
| 425 | Cardiomyopathy | Circulatory System | 0.997 | 0.952 – 1.04 | 0.894 | 2078 | 19881 | all | phecode |
| 425.1 | Primary/intrinsic cardiomyopathies | Circulatory System | 1 | 0.958 – 1.05 | 0.879 | 1989 | 19025 | all | phecode |
| 425.11 | Hypertrophic obstructive cardiomyopathy | Circulatory System | 1.08 | 0.932 – 1.25 | 0.307 | 208 | 2050 | all | phecode |
| 425.12 | Other hypertrophic cardiomyopathy | Circulatory System | 0.985 | 0.849 – 1.14 | 0.848 | 201 | 1992 | all | phecode |
| 425.2 | Secondary/extrinsic cardiomyopathies | Circulatory System | 0.987 | 0.878 – 1.11 | 0.826 | 317 | 3170 | all | phecode |
| 425.8 | Other cardiomyopathy | Circulatory System | 1.05 | 0.852 – 1.3 | 0.633 | 95 | 931 | all | phecode |
| 426 | Cardiac conduction disorders | Circulatory System | 1.01 | 0.984 – 1.03 | 0.527 | 12327 | 25440 | all | phecode |
| 426.2 | Atrioventricular [AV] block | Circulatory System | 1 | 0.955 – 1.05 | 0.898 | 1903 | 11501 | all | phecode |
| 426.21 | First degree AV block | Circulatory System | 1.01 | 0.956 – 1.08 | 0.642 | 1313 | 8899 | all | phecode |
| 426.22 | Mobitz II AV block | Circulatory System | 1.01 | 0.78 – 1.3 | 0.96 | 64 | 553 | all | phecode |
| 426.23 | Second degree AV block | Circulatory System | 0.99 | 0.862 – 1.14 | 0.89 | 216 | 1925 | all | phecode |
| 426.24 | Atrioventricular block, complete | Circulatory System | 0.994 | 0.902 – 1.1 | 0.904 | 461 | 3823 | all | phecode |
| 426.25 | Other heart block | Circulatory System | 1.05 | 0.907 – 1.21 | 0.53 | 203 | 1803 | all | phecode |
| 426.3 | Bundle branch block | Circulatory System | 0.99 | 0.946 – 1.04 | 0.657 | 2306 | 13999 | all | phecode |
| 426.31 | Right bundle branch block | Circulatory System | 0.978 | 0.925 – 1.03 | 0.442 | 1423 | 10758 | all | phecode |
| 426.32 | Left bundle branch block | Circulatory System | 0.998 | 0.933 – 1.07 | 0.945 | 969 | 8110 | all | phecode |
| 426.4 | Anomalous atrioventricular excitation | Circulatory System | 0.959 | 0.772 – 1.19 | 0.706 | 82 | 820 | all | phecode |
| 426.7 | Abnormal electrocardiogram [ECG] [EKG] | Circulatory System | 1.01 | 0.985 – 1.03 | 0.469 | 10577 | 25186 | all | phecode |
| 426.8 | Other cardiac conduction disorders | Circulatory System | 0.961 | 0.887 – 1.04 | 0.336 | 679 | 6650 | all | phecode |
| 426.9 | Cardiac pacemaker/device in situ | Circulatory System | 1.01 | 0.962 – 1.07 | 0.617 | 1754 | 11536 | all | phecode |
| 426.91 | Cardiac pacemaker in situ | Circulatory System | 1.01 | 0.946 – 1.07 | 0.833 | 1171 | 8184 | all | phecode |
| 426.92 | Cardiac defibrillator in situ | Circulatory System | 1.04 | 0.966 – 1.12 | 0.314 | 846 | 7320 | all | phecode |
| 427 | Cardiac dysrhythmias | Circulatory System | 1.01 | 0.985 – 1.03 | 0.606 | 17397 | 25735 | all | phecode |
| 427.1 | Paroxysmal tachycardia, unspecified | Circulatory System | 1.02 | 0.975 – 1.06 | 0.422 | 2474 | 18178 | all | phecode |
| 427.11 | Paroxysmal supraventricular tachycardia | Circulatory System | 1.02 | 0.971 – 1.08 | 0.385 | 1595 | 14293 | all | phecode |
| 427.12 | Paroxysmal ventricular tachycardia | Circulatory System | 1.02 | 0.961 – 1.09 | 0.499 | 1181 | 9915 | all | phecode |
| 427.2 | Atrial fibrillation and flutter | Circulatory System | 1.02 | 0.989 – 1.06 | 0.187 | 5313 | 18688 | all | phecode |
| 427.21 | Atrial fibrillation | Circulatory System | 1.02 | 0.988 – 1.06 | 0.223 | 5188 | 18409 | all | phecode |
| 427.22 | Atrial flutter | Circulatory System | 1.02 | 0.971 – 1.08 | 0.4 | 1693 | 11042 | all | phecode |
| 427.3 | Other specified cardiac dysrhythmias | Circulatory System | 1 | 0.974 – 1.03 | 0.971 | 8688 | 25552 | all | phecode |
| 427.4 | Cardiac arrest and ventricular fibrillation | Circulatory System | 0.954 | 0.873 – 1.04 | 0.299 | 536 | 5233 | all | phecode |
| 427.41 | Ventricular fibrillation and flutter | Circulatory System | 0.97 | 0.842 – 1.12 | 0.671 | 216 | 2118 | all | phecode |
| 427.42 | Cardiac arrest | Circulatory System | 0.957 | 0.864 – 1.06 | 0.399 | 410 | 4034 | all | phecode |
| 427.5 | Arrhythmia (cardiac) NOS | Circulatory System | 1 | 0.973 – 1.03 | 0.954 | 6905 | 25457 | all | phecode |
| 427.6 | Premature beats | Circulatory System | 1.01 | 0.965 – 1.05 | 0.699 | 2359 | 16248 | all | phecode |
| 427.61 | Supraventricular premature beats | Circulatory System | 1.04 | 0.957 – 1.12 | 0.381 | 670 | 6287 | all | phecode |
| 427.7 | Tachycardia NOS | Circulatory System | 1.01 | 0.981 – 1.04 | 0.477 | 5124 | 25531 | all | phecode |
| 427.8 | Sinoatrial node dysfunction (Bradycardia) | Circulatory System | 0.991 | 0.925 – 1.06 | 0.793 | 912 | 7501 | all | phecode |
| 427.9 | Palpitations | Circulatory System | 1 | 0.972 – 1.04 | 0.785 | 4430 | 24505 | all | phecode |
| 428 | Congestive heart failure; nonhypertensive | Circulatory System | 1.02 | 0.986 – 1.05 | 0.259 | 4300 | 23663 | all | phecode |
| 428.1 | Congestive heart failure (CHF) NOS | Circulatory System | 1.03 | 0.99 – 1.06 | 0.162 | 3756 | 22446 | all | phecode |
| 428.2 | Heart failure NOS | Circulatory System | 1.01 | 0.977 – 1.05 | 0.486 | 3701 | 21722 | all | phecode |
| 428.3 |
Heart failure with reduced EF [Systolic orHeart failure with reduced EF [Systolic or combined heart failure]
|
Circulatory System | 1 | 0.954 – 1.05 | 0.921 | 1765 | 14476 | all | phecode |
| 428.4 |
Heart failure with preserved EF [DiastolicHeart failure with preserved EF [Diastolic heart failure]
|
Circulatory System | 1 | 0.951 – 1.05 | 0.956 | 1648 | 13395 | all | phecode |
| 429 |
Ill-defined descriptions and complications ofIll-defined descriptions and complications of heart disease
|
Circulatory System | 1.02 | 0.996 – 1.04 | 0.102 | 12635 | 32504 | all | phecode |
| 429.1 | Heart transplant/surgery | Circulatory System | 1.05 | 0.987 – 1.11 | 0.127 | 1219 | 11696 | all | phecode |
| 429.2 | Abnormal function study of cardiovascular system | Circulatory System | 1.01 | 0.98 – 1.04 | 0.561 | 6322 | 29232 | all | phecode |
| 429.3 | Symptoms involving cardiovascular system | Circulatory System | 1.02 | 0.992 – 1.04 | 0.186 | 9650 | 32421 | all | phecode |
| 429.9 | Cardiac complications, not elsewhere classified | Circulatory System | 0.974 | 0.902 – 1.05 | 0.5 | 723 | 7072 | all | phecode |
| 430 | Intracranial hemorrhage | Circulatory System | 1.03 | 0.955 – 1.11 | 0.463 | 789 | 7842 | all | phecode |
| 430.1 | Subarachnoid hemorrhage | Circulatory System | 1.08 | 0.956 – 1.23 | 0.212 | 261 | 2610 | all | phecode |
| 430.2 | Intracerebral hemorrhage | Circulatory System | 1.03 | 0.923 – 1.14 | 0.624 | 368 | 3671 | all | phecode |
| 430.3 | Subdural hemorrhage | Circulatory System | 0.937 | 0.827 – 1.06 | 0.309 | 272 | 2680 | all | phecode |
| 433 | Cerebrovascular disease | Circulatory System | 1.02 | 0.989 – 1.05 | 0.227 | 5463 | 32242 | all | phecode |
| 433.1 | Occlusion and stenosis of precerebral arteries | Circulatory System | 1.02 | 0.976 – 1.07 | 0.346 | 1978 | 16212 | all | phecode |
| 433.11 |
Occlusion of cerebral arteries, with cerebralOcclusion of cerebral arteries, with cerebral infarction
|
Circulatory System | 0.957 | 0.842 – 1.09 | 0.496 | 260 | 2517 | all | phecode |
| 433.12 | Cerebral atherosclerosis | Circulatory System | 1.13 | 0.9 – 1.41 | 0.297 | 80 | 789 | all | phecode |
| 433.2 | Occlusion of cerebral arteries | Circulatory System | 1.04 | 0.999 – 1.09 | 0.0539 | 2437 | 21732 | all | phecode |
| 433.21 |
Cerebral artery occlusion, with cerebralCerebral artery occlusion, with cerebral infarction
|
Circulatory System | 1.04 | 0.999 – 1.09 | 0.0565 | 2357 | 21103 | all | phecode |
| 433.3 | Cerebral ischemia | Circulatory System | 1 | 0.962 – 1.04 | 0.934 | 2780 | 22868 | all | phecode |
| 433.31 | Transient cerebral ischemia | Circulatory System | 1 | 0.961 – 1.05 | 0.881 | 2409 | 20762 | all | phecode |
| 433.5 | Cerebral aneurysm | Circulatory System | 1.15 | 1.05 – 1.27 | 0.00394 | 474 | 4724 | all | phecode |
| 433.6 | Acute, but ill-defined cerebrovascular disease | Circulatory System | 1.06 | 0.96 – 1.16 | 0.264 | 464 | 4518 | all | phecode |
| 433.8 | Late effects of cerebrovascular disease | Circulatory System | 1.04 | 0.964 – 1.13 | 0.305 | 695 | 6822 | all | phecode |
| 440 | Atherosclerosis | Circulatory System | 1.06 | 1.02 – 1.11 | 0.00591 | 2477 | 19724 | all | phecode |
| 440.1 | Atherosclerosis of renal artery | Circulatory System | 1.04 | 0.907 – 1.19 | 0.571 | 231 | 2291 | all | phecode |
| 440.2 | Atherosclerosis of the extremities | Circulatory System | 1.07 | 1.02 – 1.13 | 0.00838 | 1516 | 13532 | all | phecode |
| 440.21 |
Atherosclerosis of native arteries of theAtherosclerosis of native arteries of the extremities with ulceration or gangrene
|
Circulatory System | 1.02 | 0.897 – 1.15 | 0.807 | 274 | 2669 | all | phecode |
| 440.22 |
Atherosclerosis of native arteries of theAtherosclerosis of native arteries of the extremities with intermittent claudication
|
Circulatory System | 1.07 | 1.01 – 1.15 | 0.0287 | 1040 | 9647 | all | phecode |
| 440.9 | Atherosclerosis of aorta | Circulatory System | 1.09 | 1.02 – 1.17 | 0.0166 | 846 | 8124 | all | phecode |
| 441 | Vascular insufficiency of intestine | Circulatory System | 1.01 | 0.92 – 1.1 | 0.871 | 515 | 5115 | all | phecode |
| 441.1 | Acute vascular insufficiency of intestine | Circulatory System | 0.899 | 0.785 – 1.03 | 0.124 | 240 | 2387 | all | phecode |
| 441.2 | Chronic vascular insufficiency of intestine | Circulatory System | 0.993 | 0.843 – 1.17 | 0.936 | 154 | 1536 | all | phecode |
| 442 | Other aneurysm | Circulatory System | 1.07 | 1.03 – 1.11 | 0.000881 | 2779 | 21466 | all | phecode |
| 442.1 | Aortic aneurysm | Circulatory System | 1.06 | 1.01 – 1.11 | 0.0228 | 2054 | 16492 | all | phecode |
| 442.11 | Abdominal aortic aneurysm | Circulatory System | 1.08 | 1.02 – 1.15 | 0.0116 | 1189 | 10558 | all | phecode |
| 442.2 | Aneurysm of iliac artery | Circulatory System | 1.19 | 1.02 – 1.38 | 0.0235 | 202 | 2002 | all | phecode |
| 442.3 | Aneurysm of artery of lower extremity | Circulatory System | 0.939 | 0.806 – 1.09 | 0.418 | 179 | 1765 | all | phecode |
| 442.4 | Arterial dissection | Circulatory System | 1.04 | 0.887 – 1.21 | 0.659 | 184 | 1840 | all | phecode |
| 442.8 | Aneurysm of other specified artery | Circulatory System | 1.01 | 0.906 – 1.11 | 0.924 | 399 | 3978 | all | phecode |
| 443 | Peripheral vascular disease | Circulatory System | 1.01 | 0.973 – 1.05 | 0.589 | 3086 | 24814 | all | phecode |
| 443.1 | Raynaud's syndrome | Circulatory System | 0.995 | 0.922 – 1.07 | 0.895 | 742 | 7390 | all | phecode |
| 443.7 |
Peripheral angiopathy in diseases classifiedPeripheral angiopathy in diseases classified elsewhere
|
Circulatory System | 1.04 | 0.902 – 1.19 | 0.603 | 220 | 2087 | all | phecode |
| 443.8 | Other specified peripheral vascular diseases | Circulatory System | 1.01 | 0.971 – 1.06 | 0.562 | 2557 | 21985 | all | phecode |
| 443.9 | Peripheral vascular disease, unspecified | Circulatory System | 1.04 | 0.993 – 1.08 | 0.0995 | 2341 | 18862 | all | phecode |
| 444 | Arterial embolism and thrombosis | Circulatory System | 1.06 | 0.99 – 1.14 | 0.0926 | 848 | 8423 | all | phecode |
| 444.1 |
Arterial embolism and thrombosis of lowerArterial embolism and thrombosis of lower extremity artery
|
Circulatory System | 1.01 | 0.904 – 1.14 | 0.804 | 313 | 3099 | all | phecode |
| 444.2 | Embolism and thrombosis of abdominal aorta | Circulatory System | 1.18 | 1.01 – 1.39 | 0.0425 | 155 | 1548 | all | phecode |
| 446 | Polyarteritis nodosa and allied conditions | Circulatory System | 0.965 | 0.874 – 1.06 | 0.478 | 460 | 4559 | all | phecode |
| 446.4 | Wegener's granulomatosis | Circulatory System | 0.963 | 0.787 – 1.18 | 0.717 | 109 | 1075 | all | phecode |
| 446.5 | Giant cell arteritis | Circulatory System | 0.99 | 0.779 – 1.26 | 0.934 | 79 | 749 | all | phecode |
| 446.9 | Arteritis NOS | Circulatory System | 0.986 | 0.869 – 1.12 | 0.823 | 289 | 2876 | all | phecode |
| 447 | Other disorders of arteries and arterioles | Circulatory System | 0.989 | 0.949 – 1.03 | 0.587 | 2647 | 22765 | all | phecode |
| 447.1 | Stricture of artery | Circulatory System | 1.06 | 0.965 – 1.16 | 0.228 | 523 | 5163 | all | phecode |
| 447.7 | Aortic ectasia | Circulatory System | 0.999 | 0.929 – 1.07 | 0.985 | 804 | 7938 | all | phecode |
| 448 | Disease of capillaries | Circulatory System | 0.95 | 0.896 – 1.01 | 0.0936 | 1237 | 12127 | all | phecode |
| 450 | Noninfectious disorders of lymphatic channels | Circulatory System | 0.985 | 0.941 – 1.03 | 0.507 | 2104 | 20985 | all | phecode |
| 451 | Phlebitis and thrombophlebitis | Circulatory System | 0.996 | 0.923 – 1.07 | 0.914 | 738 | 7355 | all | phecode |
| 451.2 |
Phlebitis and thrombophlebitis of lowerPhlebitis and thrombophlebitis of lower extremities
|
Circulatory System | 0.984 | 0.862 – 1.12 | 0.814 | 244 | 2437 | all | phecode |
| 452 | Other venous embolism and thrombosis | Circulatory System | 0.991 | 0.961 – 1.02 | 0.544 | 4957 | 29867 | all | phecode |
| 452.1 | Iatrogenic pulmonary embolism and infarction | Circulatory System | 1.11 | 0.98 – 1.26 | 0.1 | 276 | 2747 | all | phecode |
| 452.2 | Deep vein thrombosis [DVT] | Circulatory System | 0.968 | 0.933 – 1 | 0.0856 | 3260 | 26940 | all | phecode |
| 452.8 | Postphlebitic syndrome | Circulatory System | 0.94 | 0.796 – 1.11 | 0.463 | 154 | 1529 | all | phecode |
| 453 | Chronic venous hypertension | Circulatory System | 0.97 | 0.846 – 1.11 | 0.663 | 220 | 2168 | all | phecode |
| 454 | Varicose veins | Circulatory System | 0.996 | 0.957 – 1.04 | 0.84 | 2827 | 24555 | all | phecode |
| 454.1 | Varicose veins of lower extremity | Circulatory System | 0.996 | 0.955 – 1.04 | 0.84 | 2469 | 21426 | all | phecode |
| 454.11 | Varicose veins of lower extremity, symptomtic | Circulatory System | 0.981 | 0.931 – 1.03 | 0.464 | 1565 | 15056 | all | phecode |
| 455 | Hemorrhoids | Circulatory System | 0.98 | 0.952 – 1.01 | 0.175 | 5799 | 29818 | all | phecode |
| 456 | Chronic venous insufficiency [CVI] | Circulatory System | 0.991 | 0.954 – 1.03 | 0.644 | 3097 | 24898 | all | phecode |
| 457 |
Encounter for long-term (current) use ofEncounter for long-term (current) use of anticoagulants, antithrombotics, aspirin
|
Circulatory System | 1.02 | 0.973 – 1.07 | 0.411 | 2095 | 15309 | all | phecode |
| 457.2 |
Encounter for long-term (current) use ofEncounter for long-term (current) use of antiplatelets/antithrombotics
|
Circulatory System | 1.02 | 0.911 – 1.14 | 0.72 | 324 | 3221 | all | phecode |
| 457.3 | Encounter for long-term (current) use of aspirin | Circulatory System | 1.03 | 0.978 – 1.08 | 0.292 | 1973 | 14689 | all | phecode |
| 458 | Hypotension | Circulatory System | 1.02 | 0.989 – 1.05 | 0.222 | 5091 | 32185 | all | phecode |
| 458.1 | Orthostatic hypotension | Circulatory System | 1.01 | 0.954 – 1.07 | 0.744 | 1344 | 12938 | all | phecode |
| 458.2 | Iatrogenic hypotension | Circulatory System | 1.09 | 1.03 – 1.16 | 0.00495 | 1109 | 11012 | all | phecode |
| 458.9 | Hypotension NOS | Circulatory System | 1.02 | 0.99 – 1.05 | 0.18 | 4618 | 31186 | all | phecode |
| 459 | Other disorders of circulatory system | Circulatory System | 1 | 0.977 – 1.03 | 0.885 | 7825 | 34792 | all | phecode |
| 459.1 | Hemorrhage NOS | Circulatory System | 0.982 | 0.914 – 1.06 | 0.629 | 834 | 8215 | all | phecode |
| 459.7 | Blood vessel replaced | Circulatory System | 1.03 | 0.967 – 1.09 | 0.401 | 1305 | 13023 | all | phecode |
| 459.9 | Circulatory disease NEC | Circulatory System | 1 | 0.977 – 1.03 | 0.77 | 6706 | 33592 | all | phecode |
| 464 | Acute sinusitis | Respiratory | 0.993 | 0.963 – 1.02 | 0.659 | 4792 | 32137 | all | phecode |
| 465 |
Acute upper respiratory infections of multipleAcute upper respiratory infections of multiple or unspecified sites
|
Respiratory | 0.989 | 0.967 – 1.01 | 0.369 | 9601 | 35915 | all | phecode |
| 465.2 | Acute pharyngitis | Respiratory | 0.985 | 0.956 – 1.01 | 0.322 | 5310 | 32365 | all | phecode |
| 465.4 | Acute laryngitis and tracheitis | Respiratory | 0.982 | 0.889 – 1.08 | 0.713 | 443 | 4428 | all | phecode |
| 470 | Septal Deviations/Turbinate Hypertrophy | Respiratory | 0.967 | 0.92 – 1.02 | 0.191 | 1797 | 17640 | all | phecode |
| 471 | Nasal polyps | Respiratory | 0.963 | 0.885 – 1.05 | 0.385 | 592 | 5881 | all | phecode |
| 472 | Chronic pharyngitis and nasopharyngitis | Respiratory | 0.985 | 0.937 – 1.03 | 0.543 | 1797 | 16986 | all | phecode |
| 473 | Diseases of the larynx and vocal cords | Respiratory | 1.01 | 0.971 – 1.05 | 0.634 | 2983 | 25244 | all | phecode |
| 473.1 | Chronic laryngitis | Respiratory | 1.03 | 0.8 – 1.33 | 0.816 | 68 | 674 | all | phecode |
| 473.3 | Paralysis/spasm of vocal cords or larynx | Respiratory | 0.989 | 0.909 – 1.08 | 0.792 | 628 | 6254 | all | phecode |
| 473.4 | Voice disturbance | Respiratory | 1.02 | 0.98 – 1.07 | 0.285 | 2336 | 21975 | all | phecode |
| 474 | Acute and chronic tonsillitis | Respiratory | 1.05 | 0.977 – 1.13 | 0.184 | 880 | 7892 | all | phecode |
| 474.1 | Acute tonsillitis | Respiratory | 0.99 | 0.882 – 1.11 | 0.862 | 335 | 3181 | all | phecode |
| 474.2 | Chronic tonsillitis and adenoiditis | Respiratory | 1.05 | 0.965 – 1.13 | 0.273 | 700 | 6445 | all | phecode |
| 475 | Chronic sinusitis | Respiratory | 0.979 | 0.947 – 1.01 | 0.191 | 4378 | 27891 | all | phecode |
| 475.9 | Postnasal drip | Respiratory | 0.935 | 0.873 – 1 | 0.057 | 922 | 9017 | all | phecode |
| 476 | Allergic rhinitis | Respiratory | 0.978 | 0.957 – 0.999 | 0.0424 | 12687 | 28117 | all | phecode |
| 477 | Epistaxis or throat hemorrhage | Respiratory | 0.914 | 0.86 – 0.972 | 0.00443 | 1150 | 11318 | all | phecode |
| 478 | Throat pain | Respiratory | 1.05 | 0.947 – 1.16 | 0.354 | 426 | 4195 | all | phecode |
| 479 | Other upper respiratory disease | Respiratory | 0.984 | 0.956 – 1.01 | 0.28 | 5627 | 28048 | all | phecode |
| 480 | Pneumonia | Respiratory | 1.03 | 0.997 – 1.05 | 0.0772 | 5947 | 37034 | all | phecode |
| 480.1 | Bacterial pneumonia | Respiratory | 1 | 0.944 – 1.07 | 0.908 | 1155 | 11495 | all | phecode |
| 480.11 | Pneumococcal pneumonia | Respiratory | 1.03 | 0.944 – 1.12 | 0.506 | 568 | 5644 | all | phecode |
| 480.12 | Pseudomonal pneumonia | Respiratory | 0.896 | 0.762 – 1.05 | 0.185 | 153 | 1523 | all | phecode |
| 480.13 | MRSA pneumonia | Respiratory | 1.31 | 1.08 – 1.58 | 0.00536 | 117 | 1165 | all | phecode |
| 480.2 | Viral pneumonia | Respiratory | 0.973 | 0.841 – 1.13 | 0.709 | 202 | 1992 | all | phecode |
| 480.3 | Pneumonia due to fungus (mycoses) | Respiratory | 1.02 | 0.868 – 1.2 | 0.803 | 159 | 1590 | all | phecode |
| 480.5 | Bronchopneumonia and lung abscess | Respiratory | 1.07 | 0.897 – 1.28 | 0.457 | 135 | 1312 | all | phecode |
| 481 | Influenza | Respiratory | 0.965 | 0.912 – 1.02 | 0.218 | 1355 | 13284 | all | phecode |
| 483 | Acute bronchitis and bronchiolitis | Respiratory | 1.02 | 0.988 – 1.06 | 0.189 | 3412 | 29871 | all | phecode |
| 495 | Asthma | Respiratory | 1.02 | 0.993 – 1.04 | 0.164 | 8671 | 33569 | all | phecode |
| 495.1 | Chronic obstructive asthma | Respiratory | 1.03 | 0.934 – 1.15 | 0.516 | 397 | 3925 | all | phecode |
| 495.11 | Chronic obstructive asthma with exacerbation | Respiratory | 1.19 | 0.952 – 1.48 | 0.127 | 81 | 802 | all | phecode |
| 495.2 | Asthma with exacerbation | Respiratory | 1.01 | 0.96 – 1.07 | 0.654 | 1629 | 16033 | all | phecode |
| 496 | Chronic airway obstruction | Respiratory | 1.07 | 1.04 – 1.11 | 3.84e-06 | 5343 | 28343 | all | phecode |
| 496.1 | Emphysema | Respiratory | 1.12 | 1.07 – 1.18 | 4.46e-07 | 2134 | 19414 | all | phecode |
| 496.2 | Chronic bronchitis | Respiratory | 1.08 | 1.04 – 1.11 | 2.03e-05 | 4128 | 26624 | all | phecode |
| 496.21 | Obstructive chronic bronchitis | Respiratory | 1.08 | 1.05 – 1.12 | 8.07e-06 | 3747 | 25467 | all | phecode |
| 496.3 | Bronchiectasis | Respiratory | 1 | 0.92 – 1.09 | 0.943 | 549 | 5453 | all | phecode |
| 497 | Bronchitis | Respiratory | 1.03 | 0.979 – 1.08 | 0.272 | 1946 | 18824 | all | phecode |
| 498 | Acute bronchospasm | Respiratory | 1.02 | 0.932 – 1.12 | 0.628 | 496 | 4943 | all | phecode |
| 499 | Cystic fibrosis | Respiratory | 0.973 | 0.824 – 1.15 | 0.743 | 151 | 1510 | all | phecode |
| 500 | Lung disease due to external agents | Respiratory | 0.921 | 0.843 – 1.01 | 0.0659 | 557 | 5551 | all | phecode |
| 500.1 | Extrinsic allergic alveolitis | Respiratory | 1.07 | 0.87 – 1.32 | 0.522 | 92 | 920 | all | phecode |
| 500.2 | Pneumoconiosis | Respiratory | 0.85 | 0.661 – 1.09 | 0.203 | 78 | 764 | all | phecode |
| 501 | Pneumonitis due to inhalation of food or vomitus | Respiratory | 0.964 | 0.888 – 1.05 | 0.383 | 634 | 6225 | all | phecode |
| 502 | Postinflammatory pulmonary fibrosis | Respiratory | 1.01 | 0.937 – 1.08 | 0.831 | 815 | 8076 | all | phecode |
| 503 | Pulmonary congestion and hypostasis | Respiratory | 1.01 | 0.94 – 1.08 | 0.795 | 835 | 8243 | all | phecode |
| 504 | Other alveolar and parietoalveolar pneumonopathy | Respiratory | 1.04 | 0.952 – 1.13 | 0.418 | 595 | 5878 | all | phecode |
| 504.1 | Idiopathic fibrosing alveolitis | Respiratory | 1.05 | 0.937 – 1.18 | 0.388 | 311 | 3084 | all | phecode |
| 505 | Other pulmonary inflamation or edema | Respiratory | 1.03 | 0.976 – 1.08 | 0.295 | 1638 | 15749 | all | phecode |
| 506 | Empyema and pneumothorax | Respiratory | 1.05 | 1.01 – 1.09 | 0.0169 | 2894 | 25235 | all | phecode |
| 507 | Pleurisy; pleural effusion | Respiratory | 1.02 | 0.983 – 1.06 | 0.269 | 2916 | 26208 | all | phecode |
| 508 |
Pulmonary collapse; interstitial andPulmonary collapse; interstitial and compensatory emphysema
|
Respiratory | 1 | 0.961 – 1.05 | 0.879 | 2382 | 22588 | all | phecode |
| 509 | Respiratory failure, insufficiency, arrest | Respiratory | 1.01 | 0.976 – 1.04 | 0.591 | 4032 | 29477 | all | phecode |
| 509.1 | Respiratory failure | Respiratory | 0.995 | 0.949 – 1.04 | 0.846 | 1937 | 18949 | all | phecode |
| 509.2 | Respiratory insufficiency | Respiratory | 1 | 0.941 – 1.06 | 0.997 | 1174 | 11679 | all | phecode |
| 509.3 |
Pulmonary insufficiency or respiratory failurePulmonary insufficiency or respiratory failure following trauma and surgery
|
Respiratory | 1.02 | 0.972 – 1.08 | 0.38 | 1689 | 16489 | all | phecode |
| 509.8 |
Dependence on respirator [Ventilator] orDependence on respirator [Ventilator] or supplemental oxygen
|
Respiratory | 1.02 | 0.97 – 1.07 | 0.435 | 1741 | 17249 | all | phecode |
| 510 | Other diseases of lung | Respiratory | 1.01 | 0.977 – 1.04 | 0.674 | 5503 | 35907 | all | phecode |
| 510.2 | Lung transplant | Respiratory | 1.17 | 1.01 – 1.37 | 0.0431 | 176 | 1757 | all | phecode |
| 512 | Other symptoms of respiratory system | Respiratory | 1.01 | 0.99 – 1.03 | 0.356 | 18621 | 28154 | all | phecode |
| 512.1 | Wheezing | Respiratory | 1.03 | 0.971 – 1.08 | 0.363 | 1409 | 13516 | all | phecode |
| 512.2 | Painful respiration | Respiratory | 1.01 | 0.964 – 1.05 | 0.745 | 2309 | 21263 | all | phecode |
| 512.3 | Abnormal chest sounds | Respiratory | 0.96 | 0.852 – 1.08 | 0.506 | 291 | 2845 | all | phecode |
| 512.7 | Shortness of breath | Respiratory | 1.03 | 1.01 – 1.06 | 0.00495 | 10034 | 28081 | all | phecode |
| 512.8 | Cough | Respiratory | 1 | 0.978 – 1.03 | 0.871 | 9501 | 28148 | all | phecode |
| 512.9 | Other dyspnea | Respiratory | 1.02 | 0.992 – 1.04 | 0.194 | 10804 | 28104 | all | phecode |
| 513 | Respiratory abnormalities | Respiratory | 1.03 | 1.01 – 1.05 | 0.0106 | 12932 | 33822 | all | phecode |
| 513.3 | Hypoventilation | Respiratory | 1.05 | 0.979 – 1.12 | 0.176 | 880 | 8646 | all | phecode |
| 513.31 | Apnea | Respiratory | 1.03 | 0.935 – 1.13 | 0.564 | 462 | 4607 | all | phecode |
| 513.32 | Orthopnea | Respiratory | 1.1 | 0.96 – 1.26 | 0.17 | 220 | 2160 | all | phecode |
| 513.4 | Hyperventilation | Respiratory | 1.03 | 0.945 – 1.13 | 0.462 | 515 | 5124 | all | phecode |
| 513.8 | Disorders of diaphragm | Respiratory | 0.972 | 0.855 – 1.1 | 0.659 | 258 | 2557 | all | phecode |
| 514 | Abnormal findings examination of lungs | Respiratory | 1.03 | 1 – 1.06 | 0.0304 | 5365 | 34834 | all | phecode |
| 514.1 |
Abnormal results of function study of pulmonaryAbnormal results of function study of pulmonary system
|
Respiratory | 1 | 0.877 – 1.14 | 0.995 | 258 | 2580 | all | phecode |
| 514.2 | Solitary pulmonary nodule | Respiratory | 1.05 | 1.02 – 1.1 | 0.006 | 3018 | 27338 | all | phecode |
| 516 | Abnormal sputum | Respiratory | 1.06 | 0.985 – 1.15 | 0.118 | 735 | 7332 | all | phecode |
| 516.1 | Hemoptysis | Respiratory | 1.09 | 1.01 – 1.19 | 0.0354 | 611 | 6080 | all | phecode |
| 519 |
Other diseases of respiratory system, notOther diseases of respiratory system, not elsewhere classified
|
Respiratory | 1.02 | 0.99 – 1.04 | 0.23 | 6458 | 39057 | all | phecode |
| 519.1 | Tracheostomy complications | Respiratory | 1.09 | 0.945 – 1.25 | 0.244 | 214 | 2136 | all | phecode |
| 519.2 | Respiratory complications | Respiratory | 1.02 | 0.922 – 1.12 | 0.743 | 445 | 4430 | all | phecode |
| 519.8 | Other diseases of respiratory system, NEC | Respiratory | 1.01 | 0.962 – 1.07 | 0.623 | 1588 | 15787 | all | phecode |
| 519.9 |
Symptoms involving respiratory system and otherSymptoms involving respiratory system and other chest symptoms
|
Respiratory | 1.02 | 0.993 – 1.06 | 0.135 | 4706 | 34489 | all | phecode |
| 520 | Disorders of tooth development | Digestive | 1.03 | 0.926 – 1.15 | 0.572 | 369 | 3690 | all | phecode |
| 520.1 | Hereditary disturbances in tooth structure | Digestive | 1.06 | 0.903 – 1.25 | 0.472 | 165 | 1642 | all | phecode |
| 520.2 | Disturbances in tooth eruption | Digestive | 1.05 | 0.915 – 1.2 | 0.49 | 218 | 2172 | all | phecode |
| 521 | Diseases of hard tissues of teeth | Digestive | 1.02 | 0.955 – 1.1 | 0.504 | 898 | 8954 | all | phecode |
| 521.1 | Dental caries | Digestive | 1.03 | 0.96 – 1.11 | 0.402 | 837 | 8349 | all | phecode |
| 521.2 | Dental abrasion, erosion and attrition | Digestive | 0.905 | 0.693 – 1.18 | 0.463 | 52 | 510 | all | phecode |
| 522 | Diseases of pulp and periapical tissues | Digestive | 1.09 | 0.994 – 1.19 | 0.0692 | 535 | 5340 | all | phecode |
| 522.5 | Periapical abscess | Digestive | 1.09 | 0.987 – 1.2 | 0.0883 | 459 | 4583 | all | phecode |
| 523 | Gingival and periodontal diseases | Digestive | 0.999 | 0.925 – 1.08 | 0.987 | 718 | 7180 | all | phecode |
| 523.1 | Gingivitis | Digestive | 0.872 | 0.734 – 1.04 | 0.12 | 142 | 1418 | all | phecode |
| 523.3 | Periodontitis (acute or chronic) | Digestive | 1.05 | 0.946 – 1.17 | 0.339 | 364 | 3636 | all | phecode |
| 523.31 | Acute periodontitis | Digestive | 1.08 | 0.963 – 1.22 | 0.184 | 311 | 3109 | all | phecode |
| 523.32 | Chronic periodontitis | Digestive | 0.977 | 0.811 – 1.18 | 0.811 | 122 | 1204 | all | phecode |
| 524 | Dentofacial anomalies, including malocclusion | Digestive | 1.06 | 0.947 – 1.18 | 0.32 | 363 | 3630 | all | phecode |
| 524.3 | Anomalies of tooth position/malocclusion | Digestive | 1.06 | 0.926 – 1.22 | 0.376 | 220 | 2200 | all | phecode |
| 525 |
Other diseases of the teeth and supportingOther diseases of the teeth and supporting structures
|
Digestive | 1.08 | 1.02 – 1.16 | 0.014 | 1039 | 10382 | all | phecode |
| 525.1 | Loss of teeth or edentulism | Digestive | 1.07 | 0.96 – 1.19 | 0.229 | 374 | 3731 | all | phecode |
| 526 | Diseases of the jaws | Digestive | 1.04 | 0.995 – 1.08 | 0.0877 | 2680 | 26455 | all | phecode |
| 526.1 | Cysts of the jaws | Digestive | 1.15 | 1 – 1.31 | 0.047 | 247 | 2470 | all | phecode |
| 526.3 | Anomalies of jaw size/symmetry | Digestive | 1.1 | 0.961 – 1.26 | 0.166 | 241 | 2383 | all | phecode |
| 526.4 | Temporomandibular joint disorders | Digestive | 0.987 | 0.935 – 1.04 | 0.647 | 1504 | 15025 | all | phecode |
| 526.41 | Temporomandibular joint disorder, unspecified | Digestive | 1.01 | 0.947 – 1.07 | 0.851 | 1187 | 11858 | all | phecode |
| 526.42 | Arthralgia/ankylosis of temporomandibular joint | Digestive | 0.942 | 0.872 – 1.02 | 0.129 | 741 | 7400 | all | phecode |
| 526.5 | Inflammatory conditions of jaw | Digestive | 1.06 | 0.943 – 1.2 | 0.312 | 287 | 2864 | all | phecode |
| 526.8 | Exostosis of jaw | Digestive | 1.17 | 0.891 – 1.55 | 0.256 | 53 | 521 | all | phecode |
| 526.9 | Jaw disease NOS | Digestive | 1.02 | 0.927 – 1.12 | 0.69 | 487 | 4867 | all | phecode |
| 527 | Diseases of the salivary glands | Digestive | 0.984 | 0.937 – 1.03 | 0.522 | 1781 | 17771 | all | phecode |
| 527.1 | Hypertrophy of salivary gland | Digestive | 0.735 | 0.56 – 0.963 | 0.0257 | 58 | 579 | all | phecode |
| 527.2 | Sialoadenitis | Digestive | 0.965 | 0.869 – 1.07 | 0.508 | 394 | 3936 | all | phecode |
| 527.7 | Disturbance of salivary secretion | Digestive | 0.975 | 0.912 – 1.04 | 0.452 | 952 | 9481 | all | phecode |
| 527.8 | Other specified diseases of the salivary glands | Digestive | 0.969 | 0.853 – 1.1 | 0.633 | 254 | 2540 | all | phecode |
| 528 |
Diseases of the oral soft tissues, excludingDiseases of the oral soft tissues, excluding lesions specific for gingiva and tongue
|
Digestive | 0.989 | 0.949 – 1.03 | 0.583 | 2643 | 26197 | all | phecode |
| 528.1 | Stomatitis and mucositis | Digestive | 0.994 | 0.916 – 1.08 | 0.879 | 668 | 6657 | all | phecode |
| 528.11 | Stomatitis and mucositis (ulcerative) | Digestive | 0.94 | 0.814 – 1.08 | 0.393 | 211 | 2110 | all | phecode |
| 528.12 | Oral aphthae | Digestive | 1.05 | 0.912 – 1.21 | 0.495 | 215 | 2137 | all | phecode |
| 528.3 | Cellulitis and abscess of oral soft tissues | Digestive | 1 | 0.875 – 1.14 | 0.995 | 235 | 2338 | all | phecode |
| 528.4 | Cysts of oral soft tissues | Digestive | 0.956 | 0.795 – 1.15 | 0.631 | 124 | 1229 | all | phecode |
| 528.41 | Cyst of the salivary gland | Digestive | 0.914 | 0.726 – 1.15 | 0.44 | 77 | 760 | all | phecode |
| 528.5 | Diseases of lips | Digestive | 0.954 | 0.866 – 1.05 | 0.34 | 462 | 4602 | all | phecode |
| 528.6 | Leukoplakia of oral mucosa | Digestive | 1 | 0.838 – 1.19 | 1 | 137 | 1370 | all | phecode |
| 528.7 | Sialolithiasis | Digestive | 1.08 | 0.914 – 1.27 | 0.378 | 163 | 1623 | all | phecode |
| 529 | Diseases and other conditions of the tongue | Digestive | 0.945 | 0.874 – 1.02 | 0.154 | 690 | 6878 | all | phecode |
| 529.1 | Glossitis | Digestive | 0.945 | 0.784 – 1.14 | 0.553 | 129 | 1281 | all | phecode |
| 529.6 | Glossodynia | Digestive | 0.88 | 0.755 – 1.03 | 0.101 | 168 | 1652 | all | phecode |
| 530 | Diseases of esophagus | Digestive | 1.02 | 0.998 – 1.04 | 0.0717 | 17081 | 27931 | all | phecode |
| 530.1 | Esophagitis, GERD and related diseases | Digestive | 1.02 | 0.998 – 1.04 | 0.0737 | 16572 | 27931 | all | phecode |
| 530.11 | GERD | Digestive | 1.02 | 0.996 – 1.04 | 0.11 | 16143 | 27929 | all | phecode |
| 530.12 | Ulcer of esophagus | Digestive | 0.943 | 0.849 – 1.05 | 0.272 | 400 | 3983 | all | phecode |
| 530.13 | Barrett's esophagus | Digestive | 1.04 | 0.964 – 1.12 | 0.321 | 762 | 7584 | all | phecode |
| 530.14 | Reflux esophagitis | Digestive | 0.999 | 0.952 – 1.05 | 0.955 | 1900 | 17495 | all | phecode |
| 530.15 | Eosinophilic esophagitis | Digestive | 1.04 | 0.904 – 1.19 | 0.598 | 221 | 2210 | all | phecode |
| 530.2 | Esophageal bleeding (varices/hemorrhage) | Digestive | 1.06 | 0.976 – 1.15 | 0.173 | 651 | 6473 | all | phecode |
| 530.3 | Stricture and stenosis of esophagus | Digestive | 1.02 | 0.95 – 1.09 | 0.627 | 911 | 8971 | all | phecode |
| 530.5 | Disorders of esophageal motility | Digestive | 1.01 | 0.93 – 1.11 | 0.742 | 548 | 5432 | all | phecode |
| 530.6 | Diverticulum of esophagus, acquired | Digestive | 0.948 | 0.79 – 1.14 | 0.567 | 129 | 1265 | all | phecode |
| 530.7 | Gastroesophageal laceration-hemorrhage syndrome | Digestive | 0.815 | 0.647 – 1.03 | 0.0813 | 82 | 812 | all | phecode |
| 530.9 | Heartburn | Digestive | 1.04 | 0.985 – 1.1 | 0.162 | 1519 | 14928 | all | phecode |
| 531 | Peptic ulcer (excl. esophageal) | Digestive | 1 | 0.956 – 1.05 | 0.987 | 2073 | 20617 | all | phecode |
| 531.1 | Hemorrhage from gastrointestinal ulcer | Digestive | 0.97 | 0.875 – 1.08 | 0.569 | 391 | 3883 | all | phecode |
| 531.2 | Gastric ulcer | Digestive | 1.02 | 0.965 – 1.09 | 0.422 | 1201 | 11970 | all | phecode |
| 531.3 | Duodenal ulcer | Digestive | 0.973 | 0.884 – 1.07 | 0.575 | 467 | 4640 | all | phecode |
| 531.4 | Peptic ulcer, site unspecified | Digestive | 0.943 | 0.878 – 1.01 | 0.109 | 804 | 8018 | all | phecode |
| 531.5 | Gastrojejunal ulcer | Digestive | 1 | 0.849 – 1.18 | 0.984 | 150 | 1500 | all | phecode |
| 532 | Dysphagia | Digestive | 1.02 | 0.986 – 1.05 | 0.319 | 5585 | 26852 | all | phecode |
| 535 | Gastritis and duodenitis | Digestive | 1.04 | 0.998 – 1.08 | 0.0641 | 2799 | 27335 | all | phecode |
| 535.1 | Acute gastritis | Digestive | 1 | 0.944 – 1.06 | 0.932 | 1178 | 11750 | all | phecode |
| 535.2 | Atrophic gastritis | Digestive | 0.994 | 0.89 – 1.11 | 0.915 | 344 | 3413 | all | phecode |
| 535.6 | Duodenitis | Digestive | 0.987 | 0.88 – 1.11 | 0.818 | 334 | 3337 | all | phecode |
| 535.8 | Other specified gastritis | Digestive | 1.07 | 0.985 – 1.16 | 0.108 | 638 | 6354 | all | phecode |
| 535.9 | Gastritis and duodenitis, NOS | Digestive | 1.03 | 0.974 – 1.09 | 0.285 | 1255 | 12511 | all | phecode |
| 536 | Disorders of function of stomach | Digestive | 0.984 | 0.947 – 1.02 | 0.418 | 2911 | 27685 | all | phecode |
| 536.3 | Gastroparesis | Digestive | 1 | 0.926 – 1.08 | 0.969 | 706 | 6901 | all | phecode |
| 536.7 |
Complications of gastrostomy, colostomy andComplications of gastrostomy, colostomy and enterostomy
|
Digestive | 1.01 | 0.911 – 1.12 | 0.864 | 407 | 4059 | all | phecode |
| 536.8 |
Dyspepsia and other specified disorders ofDyspepsia and other specified disorders of function of stomach
|
Digestive | 0.992 | 0.948 – 1.04 | 0.726 | 2150 | 21094 | all | phecode |
| 537 | Other disorders of stomach and duodenum | Digestive | 0.99 | 0.953 – 1.03 | 0.579 | 3183 | 30048 | all | phecode |
| 537.1 | Lesions of stomach and duodenum | Digestive | 0.934 | 0.795 – 1.1 | 0.4 | 173 | 1725 | all | phecode |
| 539 | Bariatric surgery | Digestive | 1.01 | 0.96 – 1.07 | 0.634 | 1509 | 15074 | all | phecode |
| 540 | Appendiceal conditions | Digestive | 1.01 | 0.92 – 1.11 | 0.827 | 495 | 4948 | all | phecode |
| 540.1 | Appendicitis | Digestive | 0.982 | 0.887 – 1.09 | 0.725 | 425 | 4239 | all | phecode |
| 540.11 | Acute appendicitis | Digestive | 1.02 | 0.909 – 1.14 | 0.773 | 353 | 3511 | all | phecode |
| 550 | Abdominal hernia | Digestive | 0.996 | 0.97 – 1.02 | 0.751 | 6768 | 37731 | all | phecode |
| 550.1 | Inguinal hernia | Digestive | 0.98 | 0.932 – 1.03 | 0.419 | 1744 | 16488 | all | phecode |
| 550.2 | Diaphragmatic hernia | Digestive | 1.01 | 0.974 – 1.05 | 0.508 | 2817 | 25849 | all | phecode |
| 550.3 | Femoral hernia | Digestive | 1 | 0.831 – 1.21 | 0.972 | 131 | 1291 | all | phecode |
| 550.4 | Umbilical hernia | Digestive | 0.954 | 0.901 – 1.01 | 0.111 | 1313 | 13110 | all | phecode |
| 550.5 | Ventral hernia | Digestive | 1.01 | 0.966 – 1.05 | 0.676 | 2241 | 22163 | all | phecode |
| 550.6 | Incisional hernia | Digestive | 1.05 | 0.989 – 1.11 | 0.114 | 1313 | 13111 | all | phecode |
| 555 |
Inflammatory bowel disease and otherInflammatory bowel disease and other gastroenteritis and colitis
|
Digestive | 0.978 | 0.928 – 1.03 | 0.421 | 1536 | 15153 | all | phecode |
| 555.1 | Regional enteritis | Digestive | 0.964 | 0.9 – 1.03 | 0.298 | 919 | 9095 | all | phecode |
| 555.2 | Ulcerative colitis | Digestive | 0.997 | 0.931 – 1.07 | 0.931 | 937 | 9315 | all | phecode |
| 555.21 | Ulcerative colitis (chronic) | Digestive | 1.02 | 0.933 – 1.12 | 0.662 | 537 | 5315 | all | phecode |
| 556 | Ulceration of the lower GI tract | Digestive | 1.05 | 0.968 – 1.14 | 0.235 | 632 | 6267 | all | phecode |
| 556.1 | Ulceration of intestine | Digestive | 1.06 | 0.97 – 1.16 | 0.198 | 551 | 5451 | all | phecode |
| 556.11 |
Angiodysplasia of intestine (without mention ofAngiodysplasia of intestine (without mention of hemorrhage)
|
Digestive | 1.08 | 0.937 – 1.24 | 0.294 | 214 | 2093 | all | phecode |
| 557 | Intestinal malabsorption (non-celiac) | Digestive | 0.976 | 0.928 – 1.03 | 0.341 | 1716 | 16490 | all | phecode |
| 557.1 | Celiac disease | Digestive | 0.977 | 0.882 – 1.08 | 0.647 | 421 | 4026 | all | phecode |
| 558 | Noninfectious gastroenteritis | Digestive | 1 | 0.965 – 1.04 | 0.982 | 3458 | 26408 | all | phecode |
| 559 | Ileostomy status | Digestive | 0.985 | 0.921 – 1.05 | 0.659 | 957 | 9565 | all | phecode |
| 560 | Intestinal obstruction without mention of hernia | Digestive | 0.977 | 0.94 – 1.02 | 0.238 | 3004 | 24851 | all | phecode |
| 560.1 | Paralytic ileus | Digestive | 0.975 | 0.926 – 1.03 | 0.343 | 1627 | 15714 | all | phecode |
| 560.2 | Impaction of intestine | Digestive | 0.953 | 0.858 – 1.06 | 0.367 | 387 | 3779 | all | phecode |
| 560.3 | Peritoneal or intestinal adhesions | Digestive | 1.02 | 0.894 – 1.15 | 0.815 | 266 | 2647 | all | phecode |
| 560.4 | Other intestinal obstruction | Digestive | 0.988 | 0.939 – 1.04 | 0.647 | 1651 | 16170 | all | phecode |
| 561 | Symptoms involving digestive system | Digestive | 0.985 | 0.945 – 1.03 | 0.476 | 2608 | 21766 | all | phecode |
| 562 | Diverticulosis and diverticulitis | Digestive | 0.994 | 0.966 – 1.02 | 0.707 | 6295 | 23431 | all | phecode |
| 562.1 | Diverticulosis | Digestive | 0.996 | 0.967 – 1.02 | 0.763 | 6246 | 23383 | all | phecode |
| 562.2 | Diverticulitis | Digestive | 0.994 | 0.944 – 1.05 | 0.829 | 1611 | 15162 | all | phecode |
| 564 | Functional digestive disorders | Digestive | 0.986 | 0.964 – 1.01 | 0.225 | 11411 | 28676 | all | phecode |
| 564.1 | Irritable Bowel Syndrome | Digestive | 0.982 | 0.947 – 1.02 | 0.341 | 3457 | 22266 | all | phecode |
| 564.9 | Personal history of diseases of digestive system | Digestive | 0.98 | 0.943 – 1.02 | 0.294 | 3074 | 25861 | all | phecode |
| 565 | Anal and rectal conditions | Digestive | 0.982 | 0.947 – 1.02 | 0.325 | 3355 | 30757 | all | phecode |
| 565.1 | Anal and rectal polyp | Digestive | 0.959 | 0.906 – 1.02 | 0.157 | 1305 | 12649 | all | phecode |
| 567 | Peritonitis and retroperitoneal infections | Digestive | 0.994 | 0.939 – 1.05 | 0.824 | 1364 | 13616 | all | phecode |
| 568 | Other disorders of peritoneum | Digestive | 0.951 | 0.904 – 1 | 0.0514 | 1705 | 17038 | all | phecode |
| 568.1 |
Peritoneal adhesions (postoperative)Peritoneal adhesions (postoperative) (postinfection)
|
Digestive | 0.982 | 0.926 – 1.04 | 0.548 | 1247 | 12468 | all | phecode |
| 569 | Other disorders of intestine | Digestive | 0.993 | 0.969 – 1.02 | 0.578 | 8079 | 35231 | all | phecode |
| 569.1 | Toxic gastroenteritis and colitis | Digestive | 0.978 | 0.87 – 1.1 | 0.712 | 326 | 3260 | all | phecode |
| 569.2 | Gastrointestinal complications | Digestive | 0.992 | 0.938 – 1.05 | 0.79 | 1395 | 13933 | all | phecode |
| 571 | Chronic liver disease and cirrhosis | Digestive | 0.996 | 0.965 – 1.03 | 0.803 | 4610 | 32562 | all | phecode |
| 571.5 | Other chronic nonalcoholic liver disease | Digestive | 0.991 | 0.96 – 1.02 | 0.603 | 4342 | 32234 | all | phecode |
| 571.51 | Cirrhosis of liver without mention of alcohol | Digestive | 1.01 | 0.95 – 1.08 | 0.674 | 1018 | 10095 | all | phecode |
| 571.6 | Primary biliary cirrhosis | Digestive | 0.918 | 0.786 – 1.07 | 0.284 | 179 | 1790 | all | phecode |
| 571.8 |
Liver abscess and sequelae of chronic liverLiver abscess and sequelae of chronic liver disease
|
Digestive | 1.01 | 0.949 – 1.08 | 0.665 | 950 | 9498 | all | phecode |
| 571.81 | Portal hypertension | Digestive | 1.04 | 0.956 – 1.14 | 0.348 | 573 | 5730 | all | phecode |
| 572 | Ascites (non malignant) | Digestive | 0.982 | 0.94 – 1.03 | 0.411 | 2278 | 22675 | all | phecode |
| 573 | Other disorders of liver | Digestive | 1 | 0.972 – 1.03 | 0.965 | 5599 | 33620 | all | phecode |
| 573.1 | Chronic passive congestion of liver | Digestive | 1.01 | 0.842 – 1.2 | 0.942 | 136 | 1359 | all | phecode |
| 573.2 | Liver replaced by transplant | Digestive | 0.964 | 0.855 – 1.09 | 0.547 | 292 | 2920 | all | phecode |
| 573.3 | Hepatomegaly | Digestive | 1.06 | 0.961 – 1.16 | 0.252 | 470 | 4700 | all | phecode |
| 573.4 | Acute and subacute necrosis of liver | Digestive | 1.08 | 0.958 – 1.21 | 0.213 | 316 | 3149 | all | phecode |
| 573.5 | Jaundice (not of newborn) | Digestive | 0.991 | 0.927 – 1.06 | 0.801 | 958 | 9496 | all | phecode |
| 573.6 |
Nonspecific elevation of levels of transaminaseNonspecific elevation of levels of transaminase or lactic acid dehydrogenase [LDH]
|
Digestive | 0.969 | 0.931 – 1.01 | 0.115 | 2756 | 26470 | all | phecode |
| 573.7 | Abnormal results of function study of liver | Digestive | 0.968 | 0.932 – 1.01 | 0.0992 | 3018 | 27774 | all | phecode |
| 573.9 | Abnormal serum enzyme levels | Digestive | 0.977 | 0.947 – 1.01 | 0.15 | 4679 | 33866 | all | phecode |
| 574 | Cholelithiasis and cholecystitis | Digestive | 0.97 | 0.935 – 1.01 | 0.108 | 3177 | 30809 | all | phecode |
| 574.1 | Cholelithiasis | Digestive | 0.973 | 0.936 – 1.01 | 0.158 | 2924 | 28874 | all | phecode |
| 574.11 | Cholelithiasis with acute cholecystitis | Digestive | 0.982 | 0.878 – 1.1 | 0.754 | 342 | 3412 | all | phecode |
| 574.12 | Cholelithiasis with other cholecystitis | Digestive | 0.892 | 0.817 – 0.974 | 0.0109 | 553 | 5501 | all | phecode |
| 574.2 | Calculus of bile duct | Digestive | 0.912 | 0.849 – 0.979 | 0.0109 | 852 | 8503 | all | phecode |
| 574.3 | Cholecystitis without cholelithiasis | Digestive | 0.91 | 0.845 – 0.979 | 0.0112 | 822 | 8181 | all | phecode |
| 575 | Other biliary tract disease | Digestive | 0.96 | 0.919 – 1 | 0.0693 | 2266 | 22555 | all | phecode |
| 575.1 | Cholangitis | Digestive | 0.963 | 0.862 – 1.08 | 0.5 | 354 | 3530 | all | phecode |
| 575.2 | Obstruction of bile duct | Digestive | 0.962 | 0.885 – 1.05 | 0.361 | 621 | 6201 | all | phecode |
| 575.6 | Cholesterolosis of gallbladder | Digestive | 0.836 | 0.727 – 0.96 | 0.0114 | 207 | 2063 | all | phecode |
| 575.7 | Other disorders of gallbladder | Digestive | 0.959 | 0.896 – 1.03 | 0.22 | 939 | 9382 | all | phecode |
| 575.8 | Other disorders of biliary tract | Digestive | 0.962 | 0.905 – 1.02 | 0.212 | 1154 | 11523 | all | phecode |
| 575.9 |
Nonspecific abnormal findings on radiologicalNonspecific abnormal findings on radiological and other examination of biliary tract
|
Digestive | 0.977 | 0.859 – 1.11 | 0.726 | 260 | 2600 | all | phecode |
| 577 | Diseases of pancreas | Digestive | 0.975 | 0.933 – 1.02 | 0.253 | 2225 | 22106 | all | phecode |
| 577.1 | Acute pancreatitis | Digestive | 1 | 0.941 – 1.06 | 0.99 | 1212 | 12110 | all | phecode |
| 577.2 | Chronic pancreatitis | Digestive | 1.04 | 0.944 – 1.14 | 0.455 | 495 | 4950 | all | phecode |
| 577.3 | Cyst and pseudocyst of pancreas | Digestive | 0.987 | 0.904 – 1.08 | 0.772 | 570 | 5601 | all | phecode |
| 578 | Gastrointestinal hemorrhage | Digestive | 1 | 0.972 – 1.04 | 0.844 | 4554 | 37045 | all | phecode |
| 578.1 | Hematemesis | Digestive | 0.981 | 0.893 – 1.08 | 0.682 | 485 | 4842 | all | phecode |
| 578.2 | Blood in stool | Digestive | 1.01 | 0.97 – 1.05 | 0.651 | 2743 | 26554 | all | phecode |
| 578.8 | Hemorrhage of rectum and anus | Digestive | 1.03 | 0.982 – 1.07 | 0.249 | 2210 | 21750 | all | phecode |
| 578.9 | Hemorrhage of gastrointestinal tract | Digestive | 1.02 | 0.968 – 1.08 | 0.45 | 1562 | 15345 | all | phecode |
| 579 | Other symptoms involving abdomen and pelvis | Digestive | 0.99 | 0.959 – 1.02 | 0.53 | 4431 | 34209 | all | phecode |
| 579.2 | Splenomegaly | Digestive | 0.965 | 0.893 – 1.04 | 0.364 | 730 | 7262 | all | phecode |
| 579.8 | Nonspecific abnormal findings in stool contents | Digestive | 0.971 | 0.918 – 1.03 | 0.29 | 1410 | 13877 | all | phecode |
| 580 | Nephritis; nephrosis; renal sclerosis | Genitourinary | 0.993 | 0.945 – 1.04 | 0.779 | 1881 | 15516 | all | phecode |
| 580.1 | Glomerulonephritis | Genitourinary | 1.05 | 0.949 – 1.17 | 0.331 | 401 | 3992 | all | phecode |
| 580.11 | Proliferative glomerulonephritis | Genitourinary | 1.12 | 0.943 – 1.33 | 0.198 | 146 | 1440 | all | phecode |
| 580.12 | Non-proliferative glomerulonephritis | Genitourinary | 1.1 | 0.908 – 1.33 | 0.334 | 114 | 1128 | all | phecode |
| 580.13 | Acute glomerulonephritis, NOS | Genitourinary | 1.09 | 0.841 – 1.42 | 0.508 | 61 | 600 | all | phecode |
| 580.14 | Chronic glomerulonephritis, NOS | Genitourinary | 1.03 | 0.907 – 1.17 | 0.662 | 277 | 2760 | all | phecode |
| 580.2 |
Nephrotic syndrome without mention ofNephrotic syndrome without mention of glomerulonephritis
|
Genitourinary | 1.09 | 0.943 – 1.25 | 0.25 | 221 | 2193 | all | phecode |
| 580.3 |
Nephritis and nephropathy without mention ofNephritis and nephropathy without mention of glomerulonephritis
|
Genitourinary | 0.973 | 0.921 – 1.03 | 0.329 | 1502 | 11930 | all | phecode |
| 580.31 |
Nephritis and nephropathy in diseasesNephritis and nephropathy in diseases classified elsewhere
|
Genitourinary | 0.993 | 0.928 – 1.06 | 0.842 | 992 | 7228 | all | phecode |
| 580.32 |
Nephritis and nephropathy with pathologicalNephritis and nephropathy with pathological lesion
|
Genitourinary | 0.949 | 0.876 – 1.03 | 0.199 | 683 | 6612 | all | phecode |
| 580.4 | Renal sclerosis, NOS | Genitourinary | 0.988 | 0.883 – 1.11 | 0.828 | 340 | 3400 | all | phecode |
| 585 | Renal failure | Genitourinary | 1 | 0.974 – 1.03 | 0.981 | 7470 | 32340 | all | phecode |
| 585.1 | Acute renal failure | Genitourinary | 0.994 | 0.962 – 1.03 | 0.725 | 4265 | 27230 | all | phecode |
| 585.2 | Renal failure NOS | Genitourinary | 1.08 | 1.01 – 1.16 | 0.0309 | 832 | 8162 | all | phecode |
| 585.3 | Chronic renal failure [CKD] | Genitourinary | 1 | 0.971 – 1.03 | 0.97 | 5580 | 29470 | all | phecode |
| 585.31 | Renal dialysis | Genitourinary | 0.989 | 0.917 – 1.07 | 0.771 | 747 | 7423 | all | phecode |
| 585.32 | End stage renal disease | Genitourinary | 0.983 | 0.92 – 1.05 | 0.603 | 1007 | 9783 | all | phecode |
| 585.33 | Chronic Kidney Disease, Stage III | Genitourinary | 0.997 | 0.959 – 1.04 | 0.861 | 3209 | 21312 | all | phecode |
| 585.34 | Chronic Kidney Disease, Stage IV | Genitourinary | 0.978 | 0.915 – 1.05 | 0.511 | 977 | 9190 | all | phecode |
| 585.4 | Chronic kidney disease, Stage I or II | Genitourinary | 1.02 | 0.961 – 1.08 | 0.516 | 1227 | 11191 | all | phecode |
| 586 | Other disorders of the kidney and ureters | Genitourinary | 1 | 0.975 – 1.03 | 0.989 | 7628 | 34189 | all | phecode |
| 586.1 | Anatomical abnormatilies of kidney and ureters | Genitourinary | 0.955 | 0.855 – 1.07 | 0.419 | 349 | 3480 | all | phecode |
| 586.11 | Small kidney | Genitourinary | 0.985 | 0.854 – 1.14 | 0.834 | 210 | 2093 | all | phecode |
| 586.12 | Vesicoureteral reflux | Genitourinary | 0.962 | 0.803 – 1.15 | 0.679 | 136 | 1360 | all | phecode |
| 586.2 | Cyst of kidney, acquired | Genitourinary | 0.961 | 0.908 – 1.02 | 0.163 | 1381 | 12912 | all | phecode |
| 586.3 | Vascular disorders of kidney/hypertrophy | Genitourinary | 1.2 | 1.03 – 1.39 | 0.0216 | 187 | 1862 | all | phecode |
| 586.4 | Stricture/obstruction of ureter | Genitourinary | 0.979 | 0.933 – 1.03 | 0.402 | 1821 | 17115 | all | phecode |
| 587 | Kidney replaced by transpant | Genitourinary | 1.01 | 0.935 – 1.08 | 0.874 | 819 | 8134 | all | phecode |
| 588 | Disorders resulting from impaired renal function | Genitourinary | 1 | 0.939 – 1.07 | 0.895 | 976 | 9389 | all | phecode |
| 588.1 | Renal osteodystrophy | Genitourinary | 1.01 | 0.892 – 1.14 | 0.886 | 290 | 2900 | all | phecode |
| 588.2 | Secondary hyperparathyroidism (of renal origin) | Genitourinary | 0.983 | 0.912 – 1.06 | 0.664 | 755 | 7275 | all | phecode |
| 589 | Abnormal results of function study of kidney | Genitourinary | 1.08 | 1.01 – 1.15 | 0.025 | 1007 | 9834 | all | phecode |
| 590 | Pyelonephritis | Genitourinary | 1 | 0.948 – 1.06 | 0.982 | 1461 | 14350 | all | phecode |
| 591 | Urinary tract infection | Genitourinary | 0.996 | 0.973 – 1.02 | 0.717 | 9873 | 32513 | all | phecode |
| 592 | Cystitis and urethritis | Genitourinary | 0.995 | 0.958 – 1.03 | 0.804 | 3038 | 24207 | all | phecode |
| 592.1 | Cystitis | Genitourinary | 0.99 | 0.952 – 1.03 | 0.626 | 2880 | 23279 | all | phecode |
| 592.11 | Acute cystitis | Genitourinary | 0.987 | 0.939 – 1.04 | 0.604 | 1783 | 16452 | all | phecode |
| 592.12 | Chronic cystitis | Genitourinary | 0.964 | 0.844 – 1.1 | 0.582 | 239 | 2343 | all | phecode |
| 592.13 | Chronic interstitial cystitis | Genitourinary | 1 | 0.906 – 1.11 | 0.968 | 431 | 4310 | all | phecode |
| 592.2 | Urethritis and urethral syndrome | Genitourinary | 1.09 | 0.948 – 1.26 | 0.221 | 210 | 2093 | all | phecode |
| 593 | Hematuria | Genitourinary | 1 | 0.973 – 1.03 | 0.826 | 4859 | 32063 | all | phecode |
| 593.1 | Gross hematuria | Genitourinary | 1 | 0.949 – 1.05 | 0.999 | 1585 | 14824 | all | phecode |
| 593.2 | Microscopic hematuria | Genitourinary | 0.975 | 0.914 – 1.04 | 0.433 | 1049 | 10301 | all | phecode |
| 594 | Urinary calculus | Genitourinary | 1.01 | 0.98 – 1.03 | 0.646 | 6707 | 38209 | all | phecode |
| 594.1 | Calculus of kidney | Genitourinary | 1.01 | 0.98 – 1.03 | 0.638 | 6273 | 38051 | all | phecode |
| 594.2 | Calculus of lower urinary tract | Genitourinary | 0.989 | 0.887 – 1.1 | 0.848 | 366 | 3638 | all | phecode |
| 594.3 | Calculus of ureter | Genitourinary | 0.984 | 0.93 – 1.04 | 0.574 | 1361 | 13561 | all | phecode |
| 594.8 | Renal colic | Genitourinary | 1.02 | 0.914 – 1.14 | 0.718 | 356 | 3560 | all | phecode |
| 595 | Hydronephrosis | Genitourinary | 0.997 | 0.947 – 1.05 | 0.897 | 1670 | 16658 | all | phecode |
| 596 | Other disorders of bladder | Genitourinary | 0.997 | 0.96 – 1.04 | 0.892 | 3074 | 28020 | all | phecode |
| 596.1 | Bladder neck obstruction | Genitourinary | 0.904 | 0.815 – 1 | 0.0572 | 400 | 3942 | all | phecode |
| 596.5 | Functional disorders of bladder | Genitourinary | 1.02 | 0.969 – 1.07 | 0.467 | 1719 | 17049 | all | phecode |
| 597 | Other disorders of urethra and urinary tract | Genitourinary | 1.02 | 0.957 – 1.08 | 0.605 | 1211 | 11998 | all | phecode |
| 597.1 | Urethral stricture (not specified as infectious) | Genitourinary | 1.01 | 0.932 – 1.09 | 0.812 | 661 | 6537 | all | phecode |
| 597.2 | Urinary complications NEC | Genitourinary | 0.986 | 0.925 – 1.05 | 0.662 | 1049 | 10479 | all | phecode |
| 597.8 | Urethral hypermobility/ISD | Genitourinary | 1.1 | 0.951 – 1.28 | 0.198 | 189 | 1873 | all | phecode |
| 598 | Abnormal findings on examination of urine | Genitourinary | 1.05 | 0.88 – 1.26 | 0.566 | 138 | 1356 | all | phecode |
| 598.4 | Other cells and casts in urine | Genitourinary | 1.04 | 0.857 – 1.26 | 0.687 | 122 | 1192 | all | phecode |
| 599 | Other symptoms/disorders or the urinary system | Genitourinary | 1.01 | 0.988 – 1.03 | 0.389 | 14168 | 30681 | all | phecode |
| 599.1 | Urinary obstruction | Genitourinary | 0.906 | 0.839 – 0.979 | 0.0123 | 728 | 6861 | all | phecode |
| 599.2 | Retention of urine | Genitourinary | 0.994 | 0.964 – 1.03 | 0.718 | 5034 | 28305 | all | phecode |
| 599.3 | Dysuria | Genitourinary | 1.01 | 0.976 – 1.04 | 0.616 | 4397 | 27849 | all | phecode |
| 599.4 | Urinary incontinence | Genitourinary | 1.02 | 0.993 – 1.05 | 0.142 | 5599 | 26960 | all | phecode |
| 599.5 | Frequency of urination and polyuria | Genitourinary | 1 | 0.975 – 1.03 | 0.765 | 5498 | 28723 | all | phecode |
| 599.6 | Oliguria and anuria | Genitourinary | 1.01 | 0.927 – 1.1 | 0.827 | 599 | 5902 | all | phecode |
| 599.7 | Urethral discharge | Genitourinary | 1.06 | 0.87 – 1.29 | 0.57 | 118 | 1175 | all | phecode |
| 599.8 | Other symptoms involving urinary system | Genitourinary | 0.994 | 0.964 – 1.02 | 0.678 | 5446 | 27963 | all | phecode |
| 599.9 | Other abnormality of urination | Genitourinary | 0.996 | 0.959 – 1.04 | 0.848 | 3041 | 24877 | all | phecode |
| 600 | Hyperplasia of prostate | Genitourinary | 0.997 | 0.959 – 1.04 | 0.877 | 4063 | 11364 | all | phecode |
| 601 | Inflammatory diseases of prostate | Genitourinary | 0.958 | 0.898 – 1.02 | 0.2 | 1044 | 9665 | all | phecode |
| 601.1 | Prostatitis | Genitourinary | 0.914 | 0.831 – 1.01 | 0.0646 | 477 | 4596 | all | phecode |
| 601.11 | Acute prostatitis | Genitourinary | 0.806 | 0.667 – 0.973 | 0.0249 | 124 | 1200 | all | phecode |
| 601.12 | Chronic prostatitis | Genitourinary | 0.872 | 0.711 – 1.07 | 0.187 | 95 | 943 | all | phecode |
| 601.3 | Orchitis and epididymitis | Genitourinary | 1.05 | 0.948 – 1.17 | 0.334 | 389 | 3822 | all | phecode |
| 601.4 | Balanoposthitis | Genitourinary | 1 | 0.831 – 1.21 | 0.987 | 127 | 1224 | all | phecode |
| 601.8 |
Other inflammatory disorders of male genitalOther inflammatory disorders of male genital organs
|
Genitourinary | 0.925 | 0.785 – 1.09 | 0.356 | 161 | 1591 | all | phecode |
| 602 | Other disorders of prostate | Genitourinary | 0.98 | 0.877 – 1.1 | 0.72 | 361 | 3399 | all | phecode |
| 602.3 | Dysplasia of prostate | Genitourinary | 0.974 | 0.76 – 1.25 | 0.832 | 77 | 730 | all | phecode |
| 603 | Other disorders of testis | Genitourinary | 1.06 | 0.959 – 1.17 | 0.26 | 440 | 4354 | all | phecode |
| 603.1 | Hydrocele | Genitourinary | 1.02 | 0.899 – 1.15 | 0.803 | 293 | 2882 | all | phecode |
| 603.2 | Spermatocele | Genitourinary | 1.07 | 0.902 – 1.26 | 0.457 | 156 | 1539 | all | phecode |
| 604 | Disorders of penis | Genitourinary | 1.02 | 0.947 – 1.11 | 0.546 | 685 | 6748 | all | phecode |
| 604.1 | Redundant prepuce and phimosis/BXO | Genitourinary | 1.3 | 1.1 – 1.54 | 0.00261 | 155 | 1540 | all | phecode |
| 604.3 | Peyronie's disease | Genitourinary | 1.09 | 0.945 – 1.25 | 0.248 | 215 | 2132 | all | phecode |
| 605 | Erectile dysfunction [ED] | Genitourinary | 1.02 | 0.984 – 1.06 | 0.27 | 3776 | 12700 | all | phecode |
| 608 | Other disorders of male genital organs | Genitourinary | 0.996 | 0.946 – 1.05 | 0.887 | 1645 | 13758 | all | phecode |
| 609 | Male infertility and abnormal spermatozoa | Genitourinary | 1.01 | 0.915 – 1.12 | 0.81 | 424 | 4196 | all | phecode |
| 609.1 | Infertility, male | Genitourinary | 1.01 | 0.89 – 1.13 | 0.933 | 302 | 2992 | all | phecode |
| 609.11 | Azoospermia and oligospermia | Genitourinary | 1.04 | 0.833 – 1.29 | 0.751 | 95 | 950 | all | phecode |
| 609.2 | Abnormal spermatozoa | Genitourinary | 1.05 | 0.89 – 1.24 | 0.559 | 154 | 1519 | all | phecode |
| 610 | Benign mammary dysplasias | Genitourinary | 0.963 | 0.929 – 0.999 | 0.0466 | 3683 | 16548 | all | phecode |
| 610.1 | Cystic mastopathy | Genitourinary | 0.938 | 0.89 – 0.989 | 0.0173 | 1633 | 14191 | all | phecode |
| 610.2 | Fibroadenosis of breast | Genitourinary | 0.762 | 0.577 – 1 | 0.0537 | 60 | 600 | all | phecode |
| 610.4 | Benign neoplasm of breast | Genitourinary | 0.964 | 0.926 – 1 | 0.0838 | 2837 | 16430 | all | phecode |
| 610.8 | Other specified benign mammary dysplasias | Genitourinary | 0.924 | 0.871 – 0.98 | 0.00904 | 1269 | 12191 | all | phecode |
| 611 | Abnormal findings on mammogram or breast exam | Genitourinary | 0.99 | 0.961 – 1.02 | 0.523 | 6067 | 18690 | all | phecode |
| 611.1 | Abnormal mammogram | Genitourinary | 0.963 | 0.932 – 0.995 | 0.0236 | 4980 | 16120 | all | phecode |
| 611.11 | Mammographic microcalcification | Genitourinary | 0.982 | 0.922 – 1.05 | 0.572 | 1122 | 10394 | all | phecode |
| 611.3 | Lump or mass in breast | Genitourinary | 1.01 | 0.975 – 1.05 | 0.546 | 3549 | 18572 | all | phecode |
| 612 |
Breast conditions, congenital or relating toBreast conditions, congenital or relating to hormones
|
Genitourinary | 0.981 | 0.92 – 1.05 | 0.572 | 1051 | 10425 | all | phecode |
| 612.1 | Galactorrhea | Genitourinary | 0.928 | 0.777 – 1.11 | 0.413 | 139 | 1390 | all | phecode |
| 612.2 | Hypertrophy of breast (Gynecomastia) | Genitourinary | 0.989 | 0.918 – 1.07 | 0.771 | 800 | 7962 | all | phecode |
| 612.3 | Congenital anomalies of breast | Genitourinary | 0.992 | 0.791 – 1.25 | 0.947 | 83 | 810 | all | phecode |
| 613 | Other nonmalignant breast conditions | Genitourinary | 1 | 0.97 – 1.04 | 0.806 | 3897 | 22072 | all | phecode |
| 613.1 | Inflammatory disease of breast | Genitourinary | 0.991 | 0.908 – 1.08 | 0.83 | 593 | 5874 | all | phecode |
| 613.5 | Mastodynia | Genitourinary | 1 | 0.954 – 1.06 | 0.864 | 1675 | 16203 | all | phecode |
| 613.7 | Other signs and symptoms in breast | Genitourinary | 0.957 | 0.891 – 1.03 | 0.218 | 883 | 8754 | all | phecode |
| 613.8 | Other specified disorders of breast | Genitourinary | 1.03 | 0.957 – 1.1 | 0.473 | 932 | 9248 | all | phecode |
| 613.9 | Breast disorder NOS | Genitourinary | 1 | 0.95 – 1.06 | 0.91 | 1465 | 14174 | all | phecode |
| 614 | Inflammatory diseases of female pelvic organs | Genitourinary | 1.02 | 0.988 – 1.06 | 0.198 | 3715 | 19647 | all | phecode |
| 614.1 |
Pelvic peritoneal adhesions, femalePelvic peritoneal adhesions, female (postoperative) (postinfection)
|
Genitourinary | 1.02 | 0.91 – 1.14 | 0.75 | 337 | 3370 | all | phecode |
| 614.3 | Pelvic inflammatory disease (PID) | Genitourinary | 0.992 | 0.902 – 1.09 | 0.861 | 478 | 4773 | all | phecode |
| 614.31 | Acute inflammatory pelvic disease | Genitourinary | 1.01 | 0.822 – 1.24 | 0.915 | 94 | 933 | all | phecode |
| 614.32 | Chronic inflammatory pelvic disease | Genitourinary | 0.866 | 0.745 – 1.01 | 0.0607 | 186 | 1842 | all | phecode |
| 614.33 | Pelvic inflammatory disease, NOS | Genitourinary | 1.07 | 0.935 – 1.21 | 0.343 | 246 | 2460 | all | phecode |
| 614.4 | Inflammatory diseases of uterus, except cervix | Genitourinary | 0.975 | 0.83 – 1.14 | 0.754 | 165 | 1639 | all | phecode |
| 614.5 |
Inflammatory disease of cervix, vagina, andInflammatory disease of cervix, vagina, and vulva
|
Genitourinary | 1.04 | 1 – 1.08 | 0.0422 | 3180 | 19539 | all | phecode |
| 614.51 | Cervicitis and endocervicitis | Genitourinary | 0.972 | 0.857 – 1.1 | 0.661 | 264 | 2640 | all | phecode |
| 614.52 | Vaginitis and vulvovaginitis | Genitourinary | 1.04 | 1 – 1.09 | 0.0441 | 2732 | 18924 | all | phecode |
| 614.53 | Cyst or abscess of Bartholin's gland | Genitourinary | 1.04 | 0.871 – 1.24 | 0.668 | 132 | 1311 | all | phecode |
| 614.54 | Abscess or ulceration of vulva | Genitourinary | 1.01 | 0.88 – 1.17 | 0.856 | 225 | 2244 | all | phecode |
| 615 | Endometriosis | Genitourinary | 0.973 | 0.923 – 1.03 | 0.305 | 1585 | 14666 | all | phecode |
| 618 | Genital prolapse | Genitourinary | 0.99 | 0.945 – 1.04 | 0.662 | 2079 | 17915 | all | phecode |
| 618.1 | Prolapse of vaginal walls | Genitourinary | 0.983 | 0.93 – 1.04 | 0.546 | 1408 | 13456 | all | phecode |
| 618.2 | Uterine/Uterovaginal prolapse | Genitourinary | 0.959 | 0.877 – 1.05 | 0.359 | 542 | 5390 | all | phecode |
| 618.5 | Prolapse of vaginal vault after hysterectomy | Genitourinary | 0.981 | 0.873 – 1.1 | 0.747 | 317 | 3162 | all | phecode |
| 618.6 | Vaginal enterocele, congenital or acquired | Genitourinary | 0.948 | 0.859 – 1.05 | 0.296 | 441 | 4394 | all | phecode |
| 619 | Noninflammatory female genital disorders | Genitourinary | 0.999 | 0.969 – 1.03 | 0.953 | 5728 | 18687 | all | phecode |
| 619.1 |
Noninflammatory disorders of ovary, fallopianNoninflammatory disorders of ovary, fallopian tube, and broad ligament
|
Genitourinary | 0.971 | 0.915 – 1.03 | 0.339 | 1233 | 12082 | all | phecode |
| 619.2 | Disorders of uterus, NEC | Genitourinary | 0.962 | 0.882 – 1.05 | 0.371 | 591 | 5897 | all | phecode |
| 619.3 | Noninflammatory disorders of cervix | Genitourinary | 1.01 | 0.92 – 1.11 | 0.804 | 483 | 4823 | all | phecode |
| 619.4 | Noninflammatory disorders of vagina | Genitourinary | 0.988 | 0.947 – 1.03 | 0.589 | 2525 | 18404 | all | phecode |
| 619.5 | Noninflammatory disorders of vulva and perineum | Genitourinary | 1.04 | 0.978 – 1.1 | 0.21 | 1189 | 11717 | all | phecode |
| 620 | Dysplasia of female genital organs | Genitourinary | 1.06 | 0.953 – 1.18 | 0.282 | 395 | 3950 | all | phecode |
| 620.1 | Dysplasia of cervix | Genitourinary | 0.953 | 0.813 – 1.12 | 0.548 | 178 | 1780 | all | phecode |
| 621 | Endometrial hyperplasia | Genitourinary | 0.893 | 0.808 – 0.988 | 0.0275 | 437 | 4370 | all | phecode |
| 622 | Polyp of female genital organs | Genitourinary | 0.992 | 0.939 – 1.05 | 0.784 | 1449 | 14264 | all | phecode |
| 622.1 | Polyp of corpus uteri | Genitourinary | 0.976 | 0.918 – 1.04 | 0.454 | 1132 | 11189 | all | phecode |
| 622.2 | Mucous polyp of cervix | Genitourinary | 1 | 0.909 – 1.11 | 0.951 | 445 | 4444 | all | phecode |
| 623 | Hypertrophy of female genital organs | Genitourinary | 1.01 | 0.937 – 1.08 | 0.837 | 824 | 8165 | all | phecode |
| 624 | Symptoms involving female genital tract | Genitourinary | 0.998 | 0.943 – 1.06 | 0.951 | 1348 | 12518 | all | phecode |
| 624.1 | Dystrophy of female genital tract | Genitourinary | 0.904 | 0.785 – 1.04 | 0.157 | 216 | 2155 | all | phecode |
| 624.2 | Atrophy of female genital tract | Genitourinary | 1.26 | 0.98 – 1.62 | 0.072 | 64 | 615 | all | phecode |
| 624.9 | stress incontinence, female | Genitourinary | 1.05 | 0.998 – 1.1 | 0.0627 | 1935 | 15408 | all | phecode |
| 625 |
Pain and other symptoms associated with femalePain and other symptoms associated with female genital organs
|
Genitourinary | 0.984 | 0.955 – 1.02 | 0.314 | 5653 | 17303 | all | phecode |
| 625.1 | Dyspareunia | Genitourinary | 1.01 | 0.953 – 1.07 | 0.719 | 1267 | 12474 | all | phecode |
| 626 |
Disorders of menstruation and other abnormalDisorders of menstruation and other abnormal bleeding from female genital tract
|
Genitourinary | 0.994 | 0.964 – 1.03 | 0.719 | 5940 | 15585 | all | phecode |
| 626.1 | Irregular menstrual cycle/bleeding | Genitourinary | 0.992 | 0.957 – 1.03 | 0.652 | 4315 | 14604 | all | phecode |
| 626.11 | Absent or infrequent menstruation | Genitourinary | 0.937 | 0.878 – 1 | 0.0509 | 1062 | 8531 | all | phecode |
| 626.12 | Excessive or frequent menstruation | Genitourinary | 1.01 | 0.959 – 1.05 | 0.823 | 2097 | 11991 | all | phecode |
| 626.13 | Irregular menstrual cycle | Genitourinary | 1.01 | 0.961 – 1.06 | 0.709 | 1957 | 12265 | all | phecode |
| 626.14 | Irregular menstrual bleeding | Genitourinary | 1 | 0.937 – 1.07 | 0.96 | 970 | 8996 | all | phecode |
| 626.15 | Infertility, female, associated with anovulation | Genitourinary | 0.919 | 0.827 – 1.02 | 0.121 | 394 | 3789 | all | phecode |
| 626.2 | Dysmenorrhea | Genitourinary | 0.986 | 0.931 – 1.05 | 0.64 | 1373 | 9857 | all | phecode |
| 626.4 | Premenstrual tension syndromes | Genitourinary | 1.06 | 0.948 – 1.19 | 0.299 | 336 | 3308 | all | phecode |
| 626.8 | Infertility, female | Genitourinary | 0.908 | 0.842 – 0.978 | 0.0108 | 817 | 6741 | all | phecode |
| 627 | Menopausal and postmenopausal disorders | Genitourinary | 0.976 | 0.943 – 1.01 | 0.156 | 4560 | 14557 | all | phecode |
| 627.1 | Postmenopausal bleeding | Genitourinary | 0.946 | 0.889 – 1.01 | 0.0789 | 1146 | 10338 | all | phecode |
| 627.2 | Symptomatic menopause | Genitourinary | 0.984 | 0.945 – 1.02 | 0.425 | 3017 | 13763 | all | phecode |
| 627.21 | Symptomatic artificial menopause | Genitourinary | 0.971 | 0.822 – 1.15 | 0.729 | 152 | 1514 | all | phecode |
| 627.22 |
Need for Hormone replacement therapyNeed for Hormone replacement therapy (postmenopausal)
|
Genitourinary | 0.946 | 0.847 – 1.06 | 0.324 | 356 | 3513 | all | phecode |
| 627.3 | Postmenopausal atrophic vaginitis | Genitourinary | 0.983 | 0.919 – 1.05 | 0.606 | 997 | 9484 | all | phecode |
| 627.4 | Premenopausal menorrhagia | Genitourinary | 1.03 | 0.919 – 1.14 | 0.657 | 361 | 3580 | all | phecode |
| 627.5 | Premature menopause and other ovarian failure | Genitourinary | 0.97 | 0.862 – 1.09 | 0.618 | 309 | 3082 | all | phecode |
| 628 | Ovarian cyst | Genitourinary | 0.967 | 0.921 – 1.02 | 0.181 | 1945 | 13838 | all | phecode |
| 634 | Miscarriage; stillbirth | Pregnancy Complications | 0.946 | 0.88 – 1.02 | 0.137 | 826 | 8047 | all | phecode |
| 634.1 | Missed abortion/Hydatidiform mole | Pregnancy Complications | 0.871 | 0.769 – 0.987 | 0.0302 | 273 | 2715 | all | phecode |
| 634.3 | Ectopic pregnancy | Pregnancy Complications | 0.889 | 0.733 – 1.08 | 0.232 | 117 | 1170 | all | phecode |
| 635 |
Hemorrhage during pregnancy; childbirth andHemorrhage during pregnancy; childbirth and postpartum
|
Pregnancy Complications | 0.961 | 0.879 – 1.05 | 0.374 | 563 | 5309 | all | phecode |
| 635.2 |
Antepartum hemorrhage, abruptio placentae, andAntepartum hemorrhage, abruptio placentae, and placenta previa
|
Pregnancy Complications | 0.959 | 0.861 – 1.07 | 0.45 | 370 | 3629 | all | phecode |
| 635.3 | Placenta previa and abruptio placenta | Pregnancy Complications | 0.921 | 0.814 – 1.04 | 0.189 | 288 | 2850 | all | phecode |
| 636 |
Early or threatened labor; hemorrhage in earlyEarly or threatened labor; hemorrhage in early pregnancy
|
Pregnancy Complications | 0.993 | 0.93 – 1.06 | 0.843 | 1080 | 7870 | all | phecode |
| 636.1 | Threatened premature labor | Pregnancy Complications | 1.05 | 0.945 – 1.17 | 0.348 | 380 | 3799 | all | phecode |
| 636.2 | Early onset of delivery | Pregnancy Complications | 0.964 | 0.852 – 1.09 | 0.56 | 288 | 2868 | all | phecode |
| 636.3 | Hemorrhage in early pregnancy | Pregnancy Complications | 0.984 | 0.891 – 1.09 | 0.752 | 441 | 4365 | all | phecode |
| 636.8 | Cervical incompetence | Pregnancy Complications | 1.1 | 0.863 – 1.4 | 0.438 | 77 | 770 | all | phecode |
| 637 |
Short gestation; low birth weight; and fetalShort gestation; low birth weight; and fetal growth retardation
|
Pregnancy Complications | 0.96 | 0.773 – 1.19 | 0.71 | 85 | 850 | all | phecode |
| 642 |
Hypertension complicating pregnancyHypertension complicating pregnancy, childbirth, and the puerperium
|
Pregnancy Complications | 0.959 | 0.88 – 1.05 | 0.349 | 585 | 5725 | all | phecode |
| 642.1 | Preeclampsia and eclampsia | Pregnancy Complications | 0.956 | 0.847 – 1.08 | 0.462 | 302 | 3013 | all | phecode |
| 643 | Excessive vomiting in pregnancy | Pregnancy Complications | 0.979 | 0.858 – 1.12 | 0.75 | 252 | 2506 | all | phecode |
| 643.1 | Hyperemesis gravidarum | Pregnancy Complications | 1.06 | 0.879 – 1.29 | 0.524 | 119 | 1190 | all | phecode |
| 644 | Anemia during pregnancy | Pregnancy Complications | 0.979 | 0.85 – 1.13 | 0.77 | 224 | 2224 | all | phecode |
| 646 | Other complications of pregnancy NEC | Pregnancy Complications | 1.05 | 0.975 – 1.13 | 0.202 | 855 | 6531 | all | phecode |
| 647 |
Infectious and parasitic complicationsInfectious and parasitic complications affecting pregnancy
|
Pregnancy Complications | 0.995 | 0.858 – 1.15 | 0.948 | 211 | 2093 | all | phecode |
| 647.1 |
Infections of genitourinary tract duringInfections of genitourinary tract during pregnancy
|
Pregnancy Complications | 1.1 | 0.956 – 1.27 | 0.182 | 222 | 2213 | all | phecode |
| 647.3 | Major puerperal infection | Pregnancy Complications | 0.948 | 0.739 – 1.22 | 0.675 | 65 | 650 | all | phecode |
| 649 |
Other conditions or status of the motherOther conditions or status of the mother complicating pregnancy, childbirth, or the puerperium
|
Pregnancy Complications | 0.989 | 0.93 – 1.05 | 0.715 | 1275 | 8010 | all | phecode |
| 649.1 |
Diabetes or abnormal glucose toleranceDiabetes or abnormal glucose tolerance complicating pregnancy
|
Pregnancy Complications | 1.01 | 0.932 – 1.1 | 0.774 | 649 | 5687 | all | phecode |
| 653 |
Problems associated with amniotic cavity andProblems associated with amniotic cavity and membranes
|
Pregnancy Complications | 0.999 | 0.915 – 1.09 | 0.98 | 587 | 5463 | all | phecode |
| 654.1 |
Abnormality of organs and soft tissues ofAbnormality of organs and soft tissues of pelvis complicating pregnancy, childbirth, or the puerperium
|
Pregnancy Complications | 1.04 | 0.898 – 1.21 | 0.591 | 207 | 2055 | all | phecode |
| 654.2 | Rhesus isoimmunization in pregnancy | Pregnancy Complications | 1.03 | 0.891 – 1.19 | 0.696 | 204 | 2040 | all | phecode |
| 655 |
Known or suspected fetal abnormality affectingKnown or suspected fetal abnormality affecting management of mother
|
Pregnancy Complications | 0.967 | 0.916 – 1.02 | 0.222 | 1624 | 10064 | all | phecode |
| 655.1 | Abnormality in fetal heart rate or rhythm | Pregnancy Complications | 1.01 | 0.927 – 1.1 | 0.821 | 616 | 5533 | all | phecode |
| 656 | Other perinatal conditions of fetus or newborn | Pregnancy Complications | 1.05 | 0.979 – 1.13 | 0.172 | 898 | 7014 | all | phecode |
| 656.2 | Respiratory conditions of fetus and newborn | Pregnancy Complications | 1.14 | 0.883 – 1.46 | 0.322 | 66 | 660 | all | phecode |
| 669 | Complications of labor and delivery NEC | Pregnancy Complications | 0.99 | 0.921 – 1.06 | 0.774 | 887 | 6802 | all | phecode |
| 671 |
Venous/cerebrovascular complications embolismVenous/cerebrovascular complications embolism in pregnancy and the puerperium
|
Pregnancy Complications | 1.08 | 0.935 – 1.24 | 0.307 | 236 | 2351 | all | phecode |
| 674 | Other complications of the puerperium NEC | Pregnancy Complications | 1.02 | 0.86 – 1.21 | 0.836 | 158 | 1580 | all | phecode |
| 676 |
Other disorders of the breast associated withOther disorders of the breast associated with childbirth and disorders of lactation
|
Pregnancy Complications | 0.954 | 0.817 – 1.11 | 0.556 | 184 | 1814 | all | phecode |
| 681 | Superficial cellulitis and abscess | Dermatologic | 1.03 | 0.999 – 1.05 | 0.064 | 6500 | 38394 | all | phecode |
| 681.1 | Cellulitis and abscess of fingers/toes | Dermatologic | 0.999 | 0.941 – 1.06 | 0.973 | 1256 | 11462 | all | phecode |
| 681.2 | Cellulitis and abscess of face/neck | Dermatologic | 1.09 | 1.02 – 1.17 | 0.00818 | 1007 | 9981 | all | phecode |
| 681.3 | Cellulitis and abscess of arm/hand | Dermatologic | 1.03 | 0.982 – 1.07 | 0.248 | 2123 | 19952 | all | phecode |
| 681.5 | Cellulitis and abscess of leg, except foot | Dermatologic | 1.04 | 0.992 – 1.08 | 0.114 | 2252 | 20944 | all | phecode |
| 681.6 | Cellulitis and abscess of foot, toe | Dermatologic | 1.01 | 0.964 – 1.06 | 0.618 | 1820 | 16893 | all | phecode |
| 681.7 | Cellulitis and abscess of trunk | Dermatologic | 1.02 | 0.963 – 1.07 | 0.573 | 1572 | 15588 | all | phecode |
| 686 |
Other local infections of skin and subcutaneousOther local infections of skin and subcutaneous tissue
|
Dermatologic | 1.02 | 0.977 – 1.07 | 0.366 | 2257 | 21750 | all | phecode |
| 686.1 | Carbuncle and furuncle | Dermatologic | 1.06 | 0.974 – 1.16 | 0.173 | 558 | 5504 | all | phecode |
| 686.2 | Impetigo | Dermatologic | 1.03 | 0.927 – 1.14 | 0.614 | 414 | 4117 | all | phecode |
| 686.3 | Pilonidal cyst | Dermatologic | 1.06 | 0.903 – 1.25 | 0.471 | 160 | 1594 | all | phecode |
| 686.4 | Pyogenic granuloma | Dermatologic | 0.978 | 0.829 – 1.15 | 0.793 | 158 | 1570 | all | phecode |
| 686.5 | Pyoderma | Dermatologic | 1.12 | 0.87 – 1.45 | 0.376 | 63 | 630 | all | phecode |
| 687 | Symptoms affecting skin | Dermatologic | 0.994 | 0.945 – 1.05 | 0.832 | 1690 | 16343 | all | phecode |
| 687.1 | Rash and other nonspecific skin eruption | Dermatologic | 1 | 0.975 – 1.03 | 0.923 | 7007 | 34623 | all | phecode |
| 687.3 | Changes in skin texture | Dermatologic | 1.03 | 0.928 – 1.14 | 0.603 | 415 | 4121 | all | phecode |
| 687.4 | Disturbance of skin sensation | Dermatologic | 0.996 | 0.969 – 1.02 | 0.751 | 6375 | 34216 | all | phecode |
| 689 | Disorder of skin and subcutaneous tissue NOS | Dermatologic | 0.969 | 0.946 – 0.991 | 0.00748 | 9311 | 37335 | all | phecode |
| 690 | Erythematosquamous dermatosis | Dermatologic | 0.985 | 0.956 – 1.02 | 0.329 | 5184 | 31581 | all | phecode |
| 690.1 | Seborrheic dermatitis | Dermatologic | 0.985 | 0.955 – 1.01 | 0.314 | 5174 | 31553 | all | phecode |
| 691 | Congenital anomalies of skin | Dermatologic | 0.949 | 0.867 – 1.04 | 0.259 | 541 | 5337 | all | phecode |
| 691.3 | Congenital pigmentary anomalies of skin | Dermatologic | 0.924 | 0.714 – 1.2 | 0.548 | 62 | 613 | all | phecode |
| 694 | Dyschromia and Vitiligo | Dermatologic | 0.965 | 0.92 – 1.01 | 0.153 | 1861 | 17936 | all | phecode |
| 694.1 | Vitiligo | Dermatologic | 1.13 | 0.954 – 1.34 | 0.157 | 137 | 1347 | all | phecode |
| 694.2 | Other dyschromia | Dermatologic | 0.96 | 0.912 – 1.01 | 0.117 | 1674 | 16183 | all | phecode |
| 694.3 | Vascular disorders of skin | Dermatologic | 0.831 | 0.666 – 1.04 | 0.102 | 82 | 819 | all | phecode |
| 695 | Erythematous conditions | Dermatologic | 0.978 | 0.947 – 1.01 | 0.198 | 4120 | 30247 | all | phecode |
| 695.1 | Toxic erythema | Dermatologic | 0.874 | 0.69 – 1.11 | 0.265 | 70 | 688 | all | phecode |
| 695.2 | Bullous dermatoses | Dermatologic | 0.984 | 0.784 – 1.24 | 0.891 | 85 | 805 | all | phecode |
| 695.3 | Rosacea | Dermatologic | 0.965 | 0.919 – 1.01 | 0.158 | 1816 | 17663 | all | phecode |
| 695.4 | Lupus (localized and systemic) | Dermatologic | 1.02 | 0.944 – 1.11 | 0.581 | 672 | 6686 | all | phecode |
| 695.41 | Cutaneous lupus erythematosus | Dermatologic | 1.04 | 0.907 – 1.19 | 0.598 | 247 | 2437 | all | phecode |
| 695.42 | Systemic lupus erythematosus | Dermatologic | 1.02 | 0.937 – 1.1 | 0.681 | 637 | 6337 | all | phecode |
| 695.7 | Prurigo and Lichen | Dermatologic | 1.06 | 0.976 – 1.16 | 0.164 | 605 | 5986 | all | phecode |
| 695.8 | Other specified erythematous conditions | Dermatologic | 0.977 | 0.908 – 1.05 | 0.53 | 812 | 7980 | all | phecode |
| 695.81 | Erythema nodosum | Dermatologic | 0.751 | 0.564 – 1 | 0.0506 | 55 | 550 | all | phecode |
| 695.9 | Unspecified erythematous condition | Dermatologic | 0.98 | 0.904 – 1.06 | 0.625 | 679 | 6756 | all | phecode |
| 696 | Psoriasis and related disorders | Dermatologic | 1.04 | 0.982 – 1.1 | 0.19 | 1401 | 13832 | all | phecode |
| 696.3 | Pityriasis | Dermatologic | 0.955 | 0.764 – 1.19 | 0.684 | 92 | 904 | all | phecode |
| 696.4 | Psoriasis | Dermatologic | 1.05 | 0.992 – 1.11 | 0.0927 | 1311 | 12976 | all | phecode |
| 696.41 | Psoriasis vulgaris | Dermatologic | 1.04 | 0.979 – 1.1 | 0.203 | 1200 | 11867 | all | phecode |
| 696.42 | Psoriatic arthropathy | Dermatologic | 1.13 | 1 – 1.27 | 0.0506 | 282 | 2810 | all | phecode |
| 697 | Sarcoidosis | Dermatologic | 1.1 | 0.981 – 1.24 | 0.0996 | 333 | 3330 | all | phecode |
| 698 | Pruritus and related conditions | Dermatologic | 1.01 | 0.968 – 1.06 | 0.6 | 2254 | 21889 | all | phecode |
| 700 | Corns and callosities | Dermatologic | 1.06 | 0.998 – 1.12 | 0.0601 | 1373 | 10894 | all | phecode |
| 701 |
Other hypertrophic and atrophic conditions ofOther hypertrophic and atrophic conditions of skin
|
Dermatologic | 0.999 | 0.974 – 1.02 | 0.947 | 7651 | 38050 | all | phecode |
| 701.1 | Keratoderma, acquired | Dermatologic | 1.06 | 0.973 – 1.16 | 0.18 | 567 | 5524 | all | phecode |
| 701.2 | Scar conditions and fibrosis of skin | Dermatologic | 1.01 | 0.967 – 1.06 | 0.64 | 2184 | 21550 | all | phecode |
| 701.3 | Circumscribed scleroderma | Dermatologic | 0.989 | 0.905 – 1.08 | 0.797 | 571 | 5660 | all | phecode |
| 701.4 | Keloid scar | Dermatologic | 0.994 | 0.912 – 1.08 | 0.891 | 578 | 5716 | all | phecode |
| 701.5 | Abnormal granulation tissue | Dermatologic | 0.993 | 0.894 – 1.1 | 0.893 | 400 | 3982 | all | phecode |
| 702 |
Degenerative skin conditions and otherDegenerative skin conditions and other dermatoses
|
Dermatologic | 0.983 | 0.956 – 1.01 | 0.209 | 6956 | 29525 | all | phecode |
| 702.1 | Actinic keratosis | Dermatologic | 0.97 | 0.938 – 1 | 0.0747 | 4171 | 26529 | all | phecode |
| 702.2 | Seborrheic keratosis | Dermatologic | 0.986 | 0.957 – 1.02 | 0.349 | 5480 | 31552 | all | phecode |
| 702.4 | Degenerative skin disorders | Dermatologic | 1.2 | 0.961 – 1.49 | 0.109 | 86 | 832 | all | phecode |
| 703 | Diseases of nail, NOS | Dermatologic | 1.09 | 1.03 – 1.15 | 0.00146 | 1650 | 14562 | all | phecode |
| 703.1 | Ingrowing nail | Dermatologic | 1.04 | 0.967 – 1.11 | 0.316 | 920 | 8597 | all | phecode |
| 704 | Diseases of hair and hair follicles | Dermatologic | 0.986 | 0.95 – 1.02 | 0.462 | 3118 | 29542 | all | phecode |
| 704.1 | Alopecia | Dermatologic | 1.01 | 0.953 – 1.07 | 0.788 | 1408 | 13871 | all | phecode |
| 704.11 | Alopecia Areata | Dermatologic | 1.08 | 0.862 – 1.34 | 0.516 | 82 | 811 | all | phecode |
| 704.12 | Telogen effluvium | Dermatologic | 1.07 | 0.823 – 1.39 | 0.616 | 63 | 615 | all | phecode |
| 704.2 | Hirsutism | Dermatologic | 1.07 | 0.95 – 1.21 | 0.265 | 299 | 2946 | all | phecode |
| 704.8 |
Other specified diseases of hair and hairOther specified diseases of hair and hair follicles
|
Dermatologic | 0.973 | 0.925 – 1.02 | 0.276 | 1752 | 17189 | all | phecode |
| 705 | Disorders of sweat glands | Dermatologic | 1.07 | 0.985 – 1.17 | 0.107 | 603 | 6012 | all | phecode |
| 705.1 | Dyshidrosis | Dermatologic | 0.896 | 0.758 – 1.06 | 0.2 | 154 | 1540 | all | phecode |
| 705.3 | Hidradenitis | Dermatologic | 1.23 | 1.08 – 1.4 | 0.00207 | 245 | 2440 | all | phecode |
| 705.8 | Hyperhidrosis | Dermatologic | 1.07 | 1 – 1.14 | 0.0365 | 1112 | 10986 | all | phecode |
| 706 | Diseases of sebaceous glands | Dermatologic | 0.995 | 0.967 – 1.02 | 0.704 | 5995 | 39748 | all | phecode |
| 706.1 | Acne | Dermatologic | 0.983 | 0.942 – 1.02 | 0.407 | 2594 | 22570 | all | phecode |
| 706.2 | Sebaceous cyst | Dermatologic | 1.01 | 0.968 – 1.05 | 0.71 | 2814 | 26819 | all | phecode |
| 706.3 | Seborrhea | Dermatologic | 1.12 | 0.847 – 1.48 | 0.428 | 59 | 582 | all | phecode |
| 706.8 | Other specified diseases of sebaceous glands | Dermatologic | 1.01 | 0.964 – 1.07 | 0.57 | 1684 | 15289 | all | phecode |
| 707 | Chronic ulcer of skin | Dermatologic | 1.02 | 0.983 – 1.06 | 0.277 | 2871 | 26816 | all | phecode |
| 707.1 | Decubitus ulcer | Dermatologic | 1.02 | 0.948 – 1.1 | 0.613 | 825 | 8119 | all | phecode |
| 707.2 | Chronic ulcer of leg or foot | Dermatologic | 1.02 | 0.961 – 1.09 | 0.479 | 1108 | 9992 | all | phecode |
| 707.3 | Chronic ulcer of unspecified site | Dermatologic | 1 | 0.954 – 1.06 | 0.884 | 1641 | 16172 | all | phecode |
| 709 | Diffuse diseases of connective tissue | Dermatologic | 0.979 | 0.928 – 1.03 | 0.449 | 1477 | 14427 | all | phecode |
| 709.2 | Sicca syndrome | Dermatologic | 0.987 | 0.9 – 1.08 | 0.783 | 505 | 4986 | all | phecode |
| 709.3 | Systemic sclerosis | Dermatologic | 1.11 | 0.97 – 1.28 | 0.125 | 224 | 2209 | all | phecode |
| 709.5 | Dermatomyositis | Dermatologic | 0.916 | 0.741 – 1.13 | 0.421 | 92 | 892 | all | phecode |
| 709.6 |
Other specified diffuse diseases of connectiveOther specified diffuse diseases of connective tissue
|
Dermatologic | 0.905 | 0.725 – 1.13 | 0.38 | 90 | 892 | all | phecode |
| 709.7 | Unspecified diffuse connective tissue disease | Dermatologic | 0.966 | 0.902 – 1.04 | 0.331 | 917 | 9089 | all | phecode |
| 710 |
Osteomyelitis, periostitis, and otherOsteomyelitis, periostitis, and other infections involving bone
|
Musculoskeletal | 1.05 | 0.988 – 1.11 | 0.118 | 1254 | 12103 | all | phecode |
| 710.1 | Osteomyelitis | Musculoskeletal | 1.05 | 0.99 – 1.12 | 0.106 | 1203 | 11636 | all | phecode |
| 710.11 | Acute osteomyelitis | Musculoskeletal | 1.1 | 1.01 – 1.2 | 0.0238 | 590 | 5708 | all | phecode |
| 710.12 | Chronic osteomyelitis | Musculoskeletal | 1.07 | 0.98 – 1.17 | 0.131 | 531 | 5163 | all | phecode |
| 710.19 | Unspecified osteomyelitis | Musculoskeletal | 1.05 | 0.989 – 1.12 | 0.11 | 1153 | 11149 | all | phecode |
| 711 | Arthropathy associated with infections | Musculoskeletal | 1.01 | 0.915 – 1.12 | 0.811 | 410 | 4099 | all | phecode |
| 711.1 | Pyogenic arthritis | Musculoskeletal | 1.02 | 0.901 – 1.15 | 0.792 | 290 | 2900 | all | phecode |
| 712 | Infective connective tissue disorders | Musculoskeletal | 1.1 | 0.941 – 1.28 | 0.235 | 178 | 1776 | all | phecode |
| 713 |
Arthropathy associated with other disordersArthropathy associated with other disorders classified elsewhere
|
Musculoskeletal | 1.09 | 0.972 – 1.23 | 0.139 | 314 | 3028 | all | phecode |
| 713.5 |
Arthropathy associated with neurologicalArthropathy associated with neurological disorders
|
Musculoskeletal | 1.18 | 1.02 – 1.36 | 0.0238 | 194 | 1824 | all | phecode |
| 714 |
Rheumatoid arthritis and other inflammatoryRheumatoid arthritis and other inflammatory polyarthropathies
|
Musculoskeletal | 1.02 | 0.973 – 1.07 | 0.423 | 2086 | 18159 | all | phecode |
| 714.1 | Rheumatoid arthritis | Musculoskeletal | 1.01 | 0.958 – 1.06 | 0.761 | 1670 | 15087 | all | phecode |
| 714.2 | Juvenile rheumatoid arthritis | Musculoskeletal | 1.01 | 0.808 – 1.26 | 0.944 | 77 | 767 | all | phecode |
| 715 | Other inflammatory spondylopathies | Musculoskeletal | 1.05 | 0.992 – 1.12 | 0.088 | 1209 | 11967 | all | phecode |
| 715.1 | Sacroiliitis NEC | Musculoskeletal | 0.975 | 0.859 – 1.11 | 0.699 | 262 | 2611 | all | phecode |
| 715.2 | Ankylosing spondylitis | Musculoskeletal | 0.977 | 0.849 – 1.12 | 0.748 | 219 | 2182 | all | phecode |
| 716 | Other arthropathies | Musculoskeletal | 1.02 | 0.997 – 1.04 | 0.0841 | 13482 | 31305 | all | phecode |
| 716.1 | Unspecified polyarthropathy or polyarthritis | Musculoskeletal | 0.992 | 0.853 – 1.15 | 0.921 | 192 | 1920 | all | phecode |
| 716.2 | Unspecified monoarthritis | Musculoskeletal | 0.797 | 0.662 – 0.96 | 0.0167 | 131 | 1293 | all | phecode |
| 716.9 | Arthropathy NOS | Musculoskeletal | 1.02 | 0.997 – 1.04 | 0.0929 | 13410 | 31294 | all | phecode |
| 717 | Polymyalgia Rheumatica | Musculoskeletal | 0.918 | 0.807 – 1.04 | 0.196 | 261 | 2565 | all | phecode |
| 720 | Spinal stenosis | Musculoskeletal | 1.03 | 0.992 – 1.06 | 0.137 | 3958 | 28539 | all | phecode |
| 720.1 | Spinal stenosis of lumbar region | Musculoskeletal | 1.03 | 0.988 – 1.07 | 0.178 | 2872 | 23656 | all | phecode |
| 721 | Spondylosis and allied disorders | Musculoskeletal | 1.02 | 0.993 – 1.05 | 0.13 | 5509 | 32391 | all | phecode |
| 721.1 | Spondylosis without myelopathy | Musculoskeletal | 1.02 | 0.994 – 1.06 | 0.11 | 5153 | 31896 | all | phecode |
| 721.2 | Spondylosis with myelopathy | Musculoskeletal | 1.08 | 1.01 – 1.16 | 0.0282 | 867 | 8629 | all | phecode |
| 721.8 | Other allied disorders of spine | Musculoskeletal | 0.987 | 0.87 – 1.12 | 0.846 | 262 | 2600 | all | phecode |
| 722 | Intervertebral disc disorders | Musculoskeletal | 1.04 | 1.01 – 1.07 | 0.00406 | 6284 | 34317 | all | phecode |
| 722.1 | Displacement of intervertebral disc | Musculoskeletal | 1.03 | 0.997 – 1.07 | 0.0765 | 3591 | 31411 | all | phecode |
| 722.3 | Schmorl's nodes | Musculoskeletal | 0.97 | 0.806 – 1.17 | 0.746 | 126 | 1248 | all | phecode |
| 722.6 | Degeneration of intervertebral disc | Musculoskeletal | 1.03 | 0.999 – 1.07 | 0.0581 | 3957 | 30744 | all | phecode |
| 722.7 | Intervertebral disc disorder with myelopathy | Musculoskeletal | 1.03 | 0.943 – 1.13 | 0.496 | 515 | 5140 | all | phecode |
| 722.8 | Postlaminectomy syndrome | Musculoskeletal | 1.01 | 0.914 – 1.12 | 0.8 | 397 | 3968 | all | phecode |
| 722.9 | Other and unspecified disc disorder | Musculoskeletal | 1.05 | 0.999 – 1.1 | 0.0574 | 1932 | 19288 | all | phecode |
| 723 | Other disorders of cervical region | Musculoskeletal | 0.981 | 0.917 – 1.05 | 0.582 | 952 | 9495 | all | phecode |
| 723.1 | Torticollis | Musculoskeletal | 0.973 | 0.855 – 1.11 | 0.674 | 254 | 2522 | all | phecode |
| 724 | Other and unspecified disorders of back | Musculoskeletal | 1.01 | 0.974 – 1.04 | 0.706 | 4130 | 31954 | all | phecode |
| 724.1 | Disorders of sacrum | Musculoskeletal | 1.02 | 0.974 – 1.06 | 0.437 | 2307 | 21902 | all | phecode |
| 724.2 | Disorders of coccyx | Musculoskeletal | 1.02 | 0.92 – 1.12 | 0.748 | 426 | 4215 | all | phecode |
| 724.8 | Other symptoms referable to back | Musculoskeletal | 0.981 | 0.916 – 1.05 | 0.579 | 931 | 9295 | all | phecode |
| 724.9 | Other unspecified back disorders | Musculoskeletal | 1.05 | 0.993 – 1.11 | 0.0899 | 1412 | 14087 | all | phecode |
| 726 | Peripheral enthesopathies and allied syndromes | Musculoskeletal | 0.995 | 0.972 – 1.02 | 0.671 | 9917 | 30176 | all | phecode |
| 726.1 | Enthesopathy | Musculoskeletal | 0.987 | 0.962 – 1.01 | 0.332 | 7507 | 30106 | all | phecode |
| 726.2 | Synoviopathy | Musculoskeletal | 1.03 | 0.964 – 1.1 | 0.38 | 1015 | 9987 | all | phecode |
| 726.3 | Bursitis | Musculoskeletal | 1.04 | 0.986 – 1.09 | 0.162 | 1829 | 16722 | all | phecode |
| 726.4 | Calcaneal spur; Exostosis NOS | Musculoskeletal | 0.99 | 0.932 – 1.05 | 0.75 | 1193 | 11485 | all | phecode |
| 727 | Other disorders of synovium, tendon, and bursa | Musculoskeletal | 0.999 | 0.973 – 1.03 | 0.943 | 7425 | 30105 | all | phecode |
| 727.1 | Synovitis and tenosynovitis | Musculoskeletal | 1.02 | 0.982 – 1.06 | 0.308 | 3092 | 24998 | all | phecode |
| 727.2 | Bursitis disorders | Musculoskeletal | 0.974 | 0.879 – 1.08 | 0.613 | 419 | 4112 | all | phecode |
| 727.4 | Ganglion and cyst of synovium, tendon, and bursa | Musculoskeletal | 0.988 | 0.935 – 1.05 | 0.682 | 1400 | 13621 | all | phecode |
| 727.5 | Rupture of synovium | Musculoskeletal | 0.933 | 0.848 – 1.03 | 0.153 | 480 | 4672 | all | phecode |
| 727.6 | Rupture of tendon, nontraumatic | Musculoskeletal | 0.996 | 0.954 – 1.04 | 0.844 | 2461 | 21948 | all | phecode |
| 727.7 | Contracture of tendon (sheath) | Musculoskeletal | 0.968 | 0.888 – 1.05 | 0.453 | 591 | 5893 | all | phecode |
| 727.8 | Plica syndrome | Musculoskeletal | 1.1 | 0.914 – 1.32 | 0.319 | 130 | 1264 | all | phecode |
| 728 | Disorders of muscle, ligament, and fascia | Musculoskeletal | 1 | 0.971 – 1.03 | 0.887 | 4546 | 29473 | all | phecode |
| 728.1 | Muscular calcification and ossification | Musculoskeletal | 0.954 | 0.769 – 1.18 | 0.672 | 85 | 843 | all | phecode |
| 728.2 | Laxity of ligament or hypermobility syndrome | Musculoskeletal | 1.03 | 0.916 – 1.17 | 0.598 | 297 | 2949 | all | phecode |
| 728.7 | Fasciitis | Musculoskeletal | 0.976 | 0.938 – 1.02 | 0.243 | 2814 | 23463 | all | phecode |
| 728.71 |
Contracture of palmar fascia [Dupuytren'sContracture of palmar fascia [Dupuytren's disease]
|
Musculoskeletal | 1.05 | 0.948 – 1.16 | 0.351 | 419 | 4138 | all | phecode |
| 729 | Other disorders of soft tissues | Musculoskeletal | 0.981 | 0.947 – 1.02 | 0.287 | 3642 | 27471 | all | phecode |
| 729.1 | Rheumatism, unspecified and fibrositis | Musculoskeletal | 0.864 | 0.68 – 1.1 | 0.23 | 74 | 726 | all | phecode |
| 729.3 | Panniculitis | Musculoskeletal | 0.955 | 0.787 – 1.16 | 0.643 | 119 | 1174 | all | phecode |
| 729.7 | Nontraumatic compartment syndrome | Musculoskeletal | 1.02 | 0.793 – 1.31 | 0.872 | 67 | 664 | all | phecode |
| 731 |
Osteitis deformans and osteopathies associatedOsteitis deformans and osteopathies associated with other disorders classified elsewhere
|
Musculoskeletal | 0.96 | 0.83 – 1.11 | 0.584 | 210 | 2091 | all | phecode |
| 732 | Osteochondropathies | Musculoskeletal | 0.964 | 0.864 – 1.08 | 0.514 | 361 | 3604 | all | phecode |
| 732.1 | Juvenile osteochondrosis | Musculoskeletal | 0.941 | 0.81 – 1.09 | 0.426 | 198 | 1969 | all | phecode |
| 732.7 | Osteochondritis dissecans | Musculoskeletal | 0.874 | 0.704 – 1.09 | 0.223 | 90 | 882 | all | phecode |
| 733 | Other disorders of bone and cartilage | Musculoskeletal | 0.992 | 0.96 – 1.02 | 0.624 | 4543 | 26941 | all | phecode |
| 733.2 | Cyst of bone | Musculoskeletal | 0.961 | 0.825 – 1.12 | 0.605 | 190 | 1900 | all | phecode |
| 733.4 | Aseptic necrosis of bone | Musculoskeletal | 1.01 | 0.923 – 1.11 | 0.791 | 518 | 5160 | all | phecode |
| 733.6 | Costochondritis | Musculoskeletal | 0.994 | 0.893 – 1.11 | 0.905 | 357 | 3562 | all | phecode |
| 733.8 | Malunion and nonunion of fracture | Musculoskeletal | 1.03 | 0.961 – 1.11 | 0.379 | 822 | 8205 | all | phecode |
| 733.9 | Chondromalacia | Musculoskeletal | 0.874 | 0.703 – 1.09 | 0.224 | 96 | 960 | all | phecode |
| 735 | Acquired foot deformities | Musculoskeletal | 1.01 | 0.973 – 1.05 | 0.649 | 3417 | 29622 | all | phecode |
| 735.1 | Flat foot | Musculoskeletal | 0.948 | 0.871 – 1.03 | 0.213 | 620 | 6092 | all | phecode |
| 735.2 | Acquired toe deformities | Musculoskeletal | 1.04 | 0.984 – 1.1 | 0.162 | 1323 | 11983 | all | phecode |
| 735.21 | Hammer toe (acquired) | Musculoskeletal | 1.06 | 0.987 – 1.14 | 0.108 | 825 | 7494 | all | phecode |
| 735.23 | Hallux rigidus | Musculoskeletal | 1 | 0.904 – 1.11 | 0.95 | 405 | 4005 | all | phecode |
| 735.3 | Hallux valgus (Bunion) | Musculoskeletal | 1.02 | 0.962 – 1.07 | 0.586 | 1470 | 14295 | all | phecode |
| 736 | Other acquired deformities of limbs | Musculoskeletal | 0.998 | 0.959 – 1.04 | 0.919 | 2763 | 26555 | all | phecode |
| 736.1 | Acquired deformities of forearm | Musculoskeletal | 1.06 | 0.869 – 1.3 | 0.549 | 104 | 1033 | all | phecode |
| 736.2 | Acquired deformities of finger | Musculoskeletal | 1.04 | 0.898 – 1.2 | 0.623 | 215 | 2142 | all | phecode |
| 736.3 | Acquired deformities of hip | Musculoskeletal | 0.998 | 0.768 – 1.3 | 0.987 | 60 | 590 | all | phecode |
| 736.4 | Genu valgum or varum (acquired) | Musculoskeletal | 0.952 | 0.849 – 1.07 | 0.409 | 325 | 3247 | all | phecode |
| 736.5 | Acquired deformities of knee | Musculoskeletal | 0.937 | 0.821 – 1.07 | 0.335 | 246 | 2460 | all | phecode |
| 736.6 | Unequal leg length (acquired) | Musculoskeletal | 1.07 | 0.957 – 1.2 | 0.233 | 339 | 3365 | all | phecode |
| 737 | Curvature of spine | Musculoskeletal | 1.01 | 0.956 – 1.06 | 0.777 | 1566 | 15543 | all | phecode |
| 737.1 | Kyphosis (acquired) | Musculoskeletal | 0.989 | 0.899 – 1.09 | 0.814 | 479 | 4748 | all | phecode |
| 737.2 | Lordosis (acquired) | Musculoskeletal | 1.09 | 0.857 – 1.39 | 0.479 | 70 | 700 | all | phecode |
| 737.3 | Kyphoscoliosis and scoliosis | Musculoskeletal | 1.02 | 0.959 – 1.08 | 0.565 | 1203 | 11982 | all | phecode |
| 738 | Other acquired musculoskeletal deformity | Musculoskeletal | 1.02 | 0.978 – 1.06 | 0.366 | 2443 | 24187 | all | phecode |
| 738.4 | Acquired spondylolisthesis | Musculoskeletal | 1.05 | 0.987 – 1.12 | 0.118 | 1057 | 10542 | all | phecode |
| 739 | Contracture of joint | Musculoskeletal | 0.915 | 0.842 – 0.994 | 0.0362 | 621 | 6207 | all | phecode |
| 740 | Osteoarthrosis | Musculoskeletal | 1.01 | 0.992 – 1.03 | 0.25 | 16169 | 30268 | all | phecode |
| 740.1 | Osteoarthritis; localized | Musculoskeletal | 1.01 | 0.979 – 1.03 | 0.634 | 7005 | 27422 | all | phecode |
| 740.11 | Osteoarthrosis, localized, primary | Musculoskeletal | 1 | 0.975 – 1.03 | 0.807 | 6176 | 26155 | all | phecode |
| 740.12 | Osteoarthrosis, localized, secondary | Musculoskeletal | 0.994 | 0.92 – 1.07 | 0.872 | 713 | 7116 | all | phecode |
| 740.2 | Osteoarthrosis, generalized | Musculoskeletal | 0.99 | 0.939 – 1.04 | 0.721 | 1609 | 12092 | all | phecode |
| 740.3 |
Osteoarthrosis involving more than one siteOsteoarthrosis involving more than one site, but not specified as generalized
|
Musculoskeletal | 1.04 | 0.937 – 1.16 | 0.451 | 373 | 3586 | all | phecode |
| 740.9 | Osteoarthrosis NOS | Musculoskeletal | 1.01 | 0.989 – 1.03 | 0.341 | 15497 | 30141 | all | phecode |
| 741 | Symptoms and disorders of the joints | Musculoskeletal | 1 | 0.976 – 1.02 | 0.988 | 8555 | 35884 | all | phecode |
| 741.1 | Ankylosis of joint | Musculoskeletal | 0.924 | 0.809 – 1.05 | 0.24 | 245 | 2445 | all | phecode |
| 741.2 | Stiffness of joint | Musculoskeletal | 0.98 | 0.924 – 1.04 | 0.508 | 1268 | 12594 | all | phecode |
| 741.3 | Difficulty in walking | Musculoskeletal | 1.03 | 0.99 – 1.08 | 0.138 | 2558 | 23116 | all | phecode |
| 741.4 | Joint effusions | Musculoskeletal | 0.997 | 0.956 – 1.04 | 0.903 | 2493 | 24199 | all | phecode |
| 741.5 | Hemarthrosis | Musculoskeletal | 0.945 | 0.767 – 1.16 | 0.596 | 94 | 937 | all | phecode |
| 741.6 | Villonodular synovitis | Musculoskeletal | 1.08 | 0.845 – 1.38 | 0.54 | 68 | 666 | all | phecode |
| 742 | Derangement of joint, non-traumatic | Musculoskeletal | 1 | 0.97 – 1.03 | 0.9 | 4404 | 33771 | all | phecode |
| 742.1 | Loose body in joint | Musculoskeletal | 0.979 | 0.829 – 1.16 | 0.8 | 156 | 1554 | all | phecode |
| 742.2 |
Pathological, developmental or recurrentPathological, developmental or recurrent dislocation
|
Musculoskeletal | 1.13 | 0.998 – 1.28 | 0.0542 | 280 | 2792 | all | phecode |
| 742.8 | Articular cartilage disorder | Musculoskeletal | 0.881 | 0.769 – 1.01 | 0.0671 | 245 | 2450 | all | phecode |
| 742.9 | Other derangement of joint | Musculoskeletal | 0.996 | 0.964 – 1.03 | 0.811 | 4107 | 32972 | all | phecode |
| 743 |
Osteoporosis, osteopenia and pathologicalOsteoporosis, osteopenia and pathological fracture
|
Musculoskeletal | 0.982 | 0.959 – 1.01 | 0.147 | 9223 | 36921 | all | phecode |
| 743.1 | Osteoporosis | Musculoskeletal | 0.974 | 0.939 – 1.01 | 0.162 | 3712 | 19477 | all | phecode |
| 743.11 | Osteoporosis NOS | Musculoskeletal | 0.978 | 0.942 – 1.01 | 0.235 | 3657 | 19276 | all | phecode |
| 743.12 | Senile osteoporosis | Musculoskeletal | 0.956 | 0.882 – 1.04 | 0.277 | 703 | 5804 | all | phecode |
| 743.13 | Other specified osteoporosis | Musculoskeletal | 0.897 | 0.798 – 1.01 | 0.072 | 321 | 3141 | all | phecode |
| 743.2 | Pathologic fracture | Musculoskeletal | 0.947 | 0.889 – 1.01 | 0.092 | 1112 | 10563 | all | phecode |
| 743.21 | Pathologic fracture of vertebrae | Musculoskeletal | 0.98 | 0.891 – 1.08 | 0.688 | 475 | 4629 | all | phecode |
| 743.22 | Pathologic fracture of femur | Musculoskeletal | 1.08 | 0.902 – 1.28 | 0.418 | 143 | 1391 | all | phecode |
| 743.4 | Stress fracture | Musculoskeletal | 0.899 | 0.81 – 0.997 | 0.0438 | 407 | 4046 | all | phecode |
| 743.9 |
Osteopenia or other disorder of bone andOsteopenia or other disorder of bone and cartilage
|
Musculoskeletal | 0.986 | 0.959 – 1.01 | 0.29 | 6970 | 35237 | all | phecode |
| 745 | Pain in joint | Musculoskeletal | 0.985 | 0.966 – 1 | 0.106 | 19848 | 26918 | all | phecode |
| 747 | Cardiac and circulatory congenital anomalies | Congenital Anomalies | 0.973 | 0.931 – 1.02 | 0.229 | 2236 | 22256 | all | phecode |
| 747.1 | Cardiac congenital anomalies | Congenital Anomalies | 0.968 | 0.922 – 1.02 | 0.206 | 1767 | 17598 | all | phecode |
| 747.11 | Cardiac shunt/ heart septal defect | Congenital Anomalies | 0.978 | 0.901 – 1.06 | 0.588 | 650 | 6497 | all | phecode |
| 747.12 | Valvular heart disease/ heart chambers | Congenital Anomalies | 1.02 | 0.947 – 1.1 | 0.598 | 751 | 7480 | all | phecode |
| 747.13 | Congenital anomalies of great vessels | Congenital Anomalies | 0.969 | 0.877 – 1.07 | 0.54 | 410 | 4090 | all | phecode |
| 747.2 |
Congenital anomalies of peripheral vascularCongenital anomalies of peripheral vascular system
|
Congenital Anomalies | 0.938 | 0.855 – 1.03 | 0.177 | 501 | 5010 | all | phecode |
| 748 | Anomalies of respiratory system, congenital | Congenital Anomalies | 1.1 | 0.904 – 1.34 | 0.334 | 111 | 1110 | all | phecode |
| 749 | Congenital anomalies of face and neck | Congenital Anomalies | 0.981 | 0.898 – 1.07 | 0.666 | 555 | 5549 | all | phecode |
| 749.1 | Cleft palate | Congenital Anomalies | 1.11 | 0.904 – 1.37 | 0.312 | 97 | 970 | all | phecode |
| 749.2 | Congenital anomalies of skull and face bones | Congenital Anomalies | 0.89 | 0.731 – 1.08 | 0.25 | 105 | 1041 | all | phecode |
| 750 | Digestive congenital anomalies | Congenital Anomalies | 0.957 | 0.893 – 1.03 | 0.221 | 893 | 8919 | all | phecode |
| 750.1 | Upper gastrointestinal congenital anomalies | Congenital Anomalies | 0.978 | 0.879 – 1.09 | 0.691 | 366 | 3655 | all | phecode |
| 750.11 | Esophageal atresia/tracheoesophageal fistula | Congenital Anomalies | 0.939 | 0.779 – 1.13 | 0.51 | 119 | 1185 | all | phecode |
| 750.13 | Congenital anomalies of mouth/tongue | Congenital Anomalies | 0.92 | 0.752 – 1.13 | 0.42 | 99 | 982 | all | phecode |
| 750.14 | Congenital anomalies of esophagus | Congenital Anomalies | 1.02 | 0.853 – 1.21 | 0.851 | 134 | 1332 | all | phecode |
| 750.15 | Congenital anomalies of stomach | Congenital Anomalies | 0.881 | 0.678 – 1.14 | 0.343 | 60 | 593 | all | phecode |
| 750.2 | Lower gastrointestinal congenital anomalies | Congenital Anomalies | 0.944 | 0.862 – 1.03 | 0.214 | 531 | 5300 | all | phecode |
| 750.21 | Congenital anomalies of intestine | Congenital Anomalies | 0.964 | 0.855 – 1.09 | 0.546 | 313 | 3129 | all | phecode |
| 750.22 |
Congenital anomaly of gallbladder, bile ductsCongenital anomaly of gallbladder, bile ducts, liver, pancreas
|
Congenital Anomalies | 0.909 | 0.793 – 1.04 | 0.168 | 222 | 2214 | all | phecode |
| 751 | Genitourinary congenital anomalies | Congenital Anomalies | 0.954 | 0.91 – 1 | 0.0482 | 2008 | 19975 | all | phecode |
| 751.1 | Congenital anomalies of genital organs | Congenital Anomalies | 0.89 | 0.815 – 0.972 | 0.0094 | 574 | 5740 | all | phecode |
| 751.11 | Congenital anomalies of female genital organs | Congenital Anomalies | 0.893 | 0.802 – 0.995 | 0.0396 | 384 | 3840 | all | phecode |
| 751.12 | Congenital anomalies of male genital organs | Congenital Anomalies | 0.945 | 0.798 – 1.12 | 0.516 | 153 | 1527 | all | phecode |
| 751.2 | Congenital anomalies of urinary system | Congenital Anomalies | 0.986 | 0.932 – 1.04 | 0.62 | 1379 | 13704 | all | phecode |
| 751.21 | Cystic kidney disease | Congenital Anomalies | 0.967 | 0.905 – 1.03 | 0.327 | 976 | 9685 | all | phecode |
| 751.22 | Other specified congenital anomalies of kidney | Congenital Anomalies | 1.03 | 0.913 – 1.16 | 0.62 | 294 | 2927 | all | phecode |
| 751.3 | Obstructive genitourinary defect | Congenital Anomalies | 0.987 | 0.846 – 1.15 | 0.867 | 182 | 1809 | all | phecode |
| 752 | Nervous system congenital anomalies | Congenital Anomalies | 1.03 | 0.967 – 1.09 | 0.368 | 1133 | 11313 | all | phecode |
| 752.1 | Neural tube defects | Congenital Anomalies | 1.04 | 0.974 – 1.12 | 0.232 | 923 | 9209 | all | phecode |
| 752.11 | Spina bifida | Congenital Anomalies | 0.983 | 0.84 – 1.15 | 0.833 | 176 | 1760 | all | phecode |
| 752.2 |
Other specified congenital anomalies of nervousOther specified congenital anomalies of nervous system
|
Congenital Anomalies | 0.947 | 0.825 – 1.09 | 0.444 | 232 | 2320 | all | phecode |
| 753 | Congenital anomalies of the eye | Congenital Anomalies | 1.06 | 0.916 – 1.23 | 0.427 | 207 | 2051 | all | phecode |
| 753.1 | Congenital cataract and lens anomalies | Congenital Anomalies | 1.06 | 0.806 – 1.4 | 0.664 | 58 | 580 | all | phecode |
| 753.2 | Congenital anomalies of posterior segment of eye | Congenital Anomalies | 1.09 | 0.822 – 1.44 | 0.559 | 56 | 546 | all | phecode |
| 754 | Congenital musculoskeletal deformities of spine | Congenital Anomalies | 1.02 | 0.96 – 1.08 | 0.553 | 1216 | 12116 | all | phecode |
| 754.1 | Lumbosacral spondylolysis, congenital | Congenital Anomalies | 1.14 | 0.948 – 1.36 | 0.168 | 135 | 1333 | all | phecode |
| 754.2 | Spondylolisthesis, congenital | Congenital Anomalies | 1.02 | 0.937 – 1.11 | 0.621 | 558 | 5570 | all | phecode |
| 755 | Congenital anomalies of limbs | Congenital Anomalies | 1.02 | 0.947 – 1.1 | 0.573 | 747 | 7458 | all | phecode |
| 755.1 | Congenital deformities of feet | Congenital Anomalies | 1 | 0.898 – 1.12 | 0.978 | 368 | 3663 | all | phecode |
| 755.4 |
Congenital anomalies of upper limb, includingCongenital anomalies of upper limb, including shoulder girdle
|
Congenital Anomalies | 0.931 | 0.741 – 1.17 | 0.543 | 74 | 740 | all | phecode |
| 755.6 |
Other congenital anomalies of lower limbOther congenital anomalies of lower limb, including pelvic girdle
|
Congenital Anomalies | 1.07 | 0.95 – 1.2 | 0.273 | 321 | 3205 | all | phecode |
| 755.61 | Congenital hip dysplasia and deformity | Congenital Anomalies | 1.11 | 0.951 – 1.29 | 0.19 | 185 | 1847 | all | phecode |
| 756 | Other congenital musculoskeletal anomalies | Congenital Anomalies | 0.966 | 0.913 – 1.02 | 0.236 | 1358 | 13579 | all | phecode |
| 756.1 | Congenital anomalies of abdominal wall; diaphram | Congenital Anomalies | 0.955 | 0.746 – 1.22 | 0.718 | 68 | 680 | all | phecode |
| 756.2 |
Pectus and other congenital anomalies ofPectus and other congenital anomalies of ribs/sternum
|
Congenital Anomalies | 0.67 | 0.516 – 0.869 | 0.00259 | 71 | 694 | all | phecode |
| 756.3 |
Congenital anomalies of muscle, tendon, fasciaCongenital anomalies of muscle, tendon, fascia, and connective tissue
|
Congenital Anomalies | 0.978 | 0.873 – 1.1 | 0.706 | 335 | 3346 | all | phecode |
| 756.5 | Congenital osteodystrophies | Congenital Anomalies | 0.986 | 0.923 – 1.05 | 0.668 | 1003 | 10014 | all | phecode |
| 757 | Congenital anomalies of the integument | Congenital Anomalies | 0.952 | 0.86 – 1.05 | 0.349 | 401 | 4001 | all | phecode |
| 758 | Chromosomal anomalies and genetic disorders | Congenital Anomalies | 0.791 | 0.679 – 0.923 | 0.00287 | 185 | 1845 | all | phecode |
| 758.1 | Chromosomal anomalies | Congenital Anomalies | 0.884 | 0.743 – 1.05 | 0.168 | 135 | 1349 | all | phecode |
| 759 | Other and unspecified congenital anomalies | Congenital Anomalies | 0.929 | 0.851 – 1.01 | 0.1 | 557 | 5566 | all | phecode |
| 759.1 | Anomalies of endocrine glands, congenital | Congenital Anomalies | 0.88 | 0.691 – 1.12 | 0.301 | 71 | 710 | all | phecode |
| 760 | Back pain | Symptoms | 1.01 | 0.994 – 1.03 | 0.167 | 16037 | 30719 | all | phecode |
| 761 | Cervicalgia | Symptoms | 1.03 | 1 – 1.06 | 0.0284 | 6528 | 39755 | all | phecode |
| 763 |
Thoracic or lumbosacral neuritis orThoracic or lumbosacral neuritis or radiculitis, unspecified
|
Symptoms | 1.04 | 1 – 1.07 | 0.0423 | 3657 | 32599 | all | phecode |
| 764 | Sciatica | Symptoms | 1.03 | 0.991 – 1.06 | 0.152 | 3542 | 32015 | all | phecode |
| 765 | Cervical radiculitis | Symptoms | 1.07 | 1.02 – 1.12 | 0.00833 | 1799 | 17851 | all | phecode |
| 766 | Neuralgia, neuritis, and radiculitis NOS | Symptoms | 1.03 | 0.998 – 1.06 | 0.0664 | 5124 | 37132 | all | phecode |
| 767 | Cervicocranial/Cervicobrachial syndrome | Symptoms | 1.21 | 1 – 1.47 | 0.0484 | 117 | 1168 | all | phecode |
| 769 | Nonallopathic lesions NEC | Symptoms | 0.999 | 0.939 – 1.06 | 0.986 | 1131 | 11220 | all | phecode |
| 770 | Myalgia and myositis unspecified | Symptoms | 1.01 | 0.978 – 1.04 | 0.641 | 5533 | 34303 | all | phecode |
| 771 | Musculoskeletal symptoms referable to limbs | Symptoms | 0.991 | 0.961 – 1.02 | 0.58 | 4799 | 35575 | all | phecode |
| 771.1 | Swelling of limb | Symptoms | 0.993 | 0.965 – 1.02 | 0.647 | 5743 | 35539 | all | phecode |
| 771.2 | Cramp of limb | Symptoms | 1.01 | 0.947 – 1.08 | 0.781 | 1079 | 10568 | all | phecode |
| 772 | Symptoms of the muscles | Symptoms | 0.986 | 0.941 – 1.03 | 0.543 | 2042 | 20221 | all | phecode |
| 772.1 | Muscular wasting and disuse atrophy | Symptoms | 1.04 | 0.938 – 1.15 | 0.465 | 422 | 4199 | all | phecode |
| 772.2 | Spasm of muscle | Symptoms | 0.985 | 0.943 – 1.03 | 0.482 | 2299 | 22726 | all | phecode |
| 772.3 | Muscle weakness | Symptoms | 1 | 0.965 – 1.04 | 0.892 | 2949 | 28064 | all | phecode |
| 772.4 | Rhabdomyolysis | Symptoms | 0.98 | 0.836 – 1.15 | 0.807 | 159 | 1572 | all | phecode |
| 772.6 | Facial weakness | Symptoms | 0.974 | 0.885 – 1.07 | 0.588 | 478 | 4742 | all | phecode |
| 780 | Hypothermia/Chills | Symptoms | 1.02 | 0.925 – 1.12 | 0.694 | 453 | 4514 | all | phecode |
| 781 |
Symptoms involving nervous and musculoskeletalSymptoms involving nervous and musculoskeletal systems
|
Symptoms | 1.01 | 0.969 – 1.05 | 0.712 | 2822 | 26225 | all | phecode |
| 781.1 | Loss of height | Symptoms | 0.869 | 0.724 – 1.04 | 0.131 | 130 | 1269 | all | phecode |
| 781.2 | Abnormal posture | Symptoms | 1 | 0.767 – 1.31 | 0.988 | 57 | 567 | all | phecode |
| 782.3 | Edema | Symptoms | 1.01 | 0.986 – 1.04 | 0.333 | 5874 | 36788 | all | phecode |
| 782.6 | Pallor and flushing | Symptoms | 0.923 | 0.862 – 0.989 | 0.0231 | 927 | 9252 | all | phecode |
| 783 | Fever of unknown origin | Symptoms | 0.998 | 0.971 – 1.03 | 0.91 | 5733 | 40720 | all | phecode |
| 783.1 | Postprocedural fever | Symptoms | 1.03 | 0.913 – 1.16 | 0.628 | 300 | 2992 | all | phecode |
| 785 | Abdominal pain | Symptoms | 1.01 | 0.992 – 1.03 | 0.263 | 16458 | 30297 | all | phecode |
| 788 | Syncope and collapse | Symptoms | 1.02 | 0.984 – 1.05 | 0.304 | 3851 | 35832 | all | phecode |
| 789 | Nausea and vomiting | Symptoms | 0.986 | 0.964 – 1.01 | 0.215 | 10568 | 36098 | all | phecode |
| 789.1 | Persistent vomiting | Symptoms | 1.01 | 0.938 – 1.09 | 0.801 | 798 | 7924 | all | phecode |
| 790 | Nonspecific findings on examination of blood | Symptoms | 1.01 | 0.964 – 1.05 | 0.762 | 2363 | 22690 | all | phecode |
| 790.1 | Elevated sedimentation rate | Symptoms | 0.9 | 0.786 – 1.03 | 0.126 | 236 | 2322 | all | phecode |
| 790.6 | Other abnormal blood chemistry | Symptoms | 0.983 | 0.959 – 1.01 | 0.194 | 7539 | 37788 | all | phecode |
| 790.8 | Elevated C-reactive protein (CRP) | Symptoms | 0.998 | 0.888 – 1.12 | 0.98 | 309 | 3075 | all | phecode |
| 790.9 | Abnormal arterial blood gases | Symptoms | 1.1 | 0.939 – 1.3 | 0.231 | 155 | 1521 | all | phecode |
| 791 | Gangrene | Symptoms | 1.04 | 0.926 – 1.17 | 0.496 | 313 | 3115 | all | phecode |
| 792 |
Abnormal Papanicolaou smear of cervix andAbnormal Papanicolaou smear of cervix and cervical HPV
|
Genitourinary | 1.01 | 0.966 – 1.05 | 0.749 | 2820 | 14872 | all | phecode |
| 792.1 |
Papanicolaou smear of cervix or vagina withPapanicolaou smear of cervix or vagina with atypical squamous cells
|
Genitourinary | 1.03 | 0.965 – 1.1 | 0.385 | 1100 | 9861 | all | phecode |
| 794 |
Abnormal results of other function studiesAbnormal results of other function studies (bladder, pancreas, placenta, spleen, etc)
|
Symptoms | 0.969 | 0.885 – 1.06 | 0.504 | 515 | 5133 | all | phecode |
| 795 |
Other and nonspecific abnormal cytologicalOther and nonspecific abnormal cytological, histological and immunological findings
|
Symptoms | 1.01 | 0.966 – 1.06 | 0.656 | 2182 | 20242 | all | phecode |
| 795.8 | Abnormal tumor markers | Symptoms | 0.984 | 0.936 – 1.03 | 0.525 | 1745 | 15551 | all | phecode |
| 795.81 | Elevated carcinoembryonic antigen [CEA] | Symptoms | 1.03 | 0.794 – 1.33 | 0.845 | 61 | 605 | all | phecode |
| 795.82 | Elevated cancer antigen 125 [CA 125] | Symptoms | 0.95 | 0.822 – 1.1 | 0.49 | 201 | 2000 | all | phecode |
| 796 | Elevated prostate specific antigen [PSA] | Genitourinary | 0.979 | 0.933 – 1.03 | 0.399 | 2125 | 9930 | all | phecode |
| 797 | Shock | Symptoms | 0.945 | 0.868 – 1.03 | 0.194 | 605 | 6050 | all | phecode |
| 797.1 | Cardiogenic shock | Symptoms | 0.959 | 0.838 – 1.1 | 0.546 | 242 | 2420 | all | phecode |
| 798 | Malaise and fatigue | Symptoms | 1.01 | 0.985 – 1.03 | 0.536 | 11539 | 35196 | all | phecode |
| 798.1 | Chronic fatigue syndrome | Symptoms | 0.979 | 0.932 – 1.03 | 0.392 | 1823 | 17795 | all | phecode |
| 800 | Fracture of lower limb | Injuries & Poisonings | 1.04 | 0.992 – 1.08 | 0.114 | 2344 | 22951 | all | phecode |
| 800.1 | Fracture of neck of femur | Injuries & Poisonings | 1.08 | 0.986 – 1.18 | 0.0984 | 512 | 4961 | all | phecode |
| 800.2 | Fracture of unspecified part of femur | Injuries & Poisonings | 1.06 | 0.977 – 1.14 | 0.169 | 670 | 6582 | all | phecode |
| 800.3 | Fracture of tibia and fibula | Injuries & Poisonings | 1.02 | 0.948 – 1.09 | 0.66 | 898 | 8966 | all | phecode |
| 800.4 | Fracture of patella | Injuries & Poisonings | 1.12 | 1.01 – 1.26 | 0.0398 | 346 | 3456 | all | phecode |
| 801 | Fracture of ankle and foot | Injuries & Poisonings | 1.02 | 0.978 – 1.07 | 0.336 | 2358 | 22645 | all | phecode |
| 801.1 | Fracture of foot | Injuries & Poisonings | 1.04 | 0.978 – 1.11 | 0.202 | 1120 | 11178 | all | phecode |
| 802 | Fracture of pelvis | Injuries & Poisonings | 1.07 | 0.958 – 1.19 | 0.239 | 380 | 3765 | all | phecode |
| 803 | Fracture of upper limb | Injuries & Poisonings | 0.998 | 0.953 – 1.04 | 0.924 | 2051 | 20360 | all | phecode |
| 803.1 | Fracture of humerus | Injuries & Poisonings | 1.02 | 0.949 – 1.11 | 0.531 | 734 | 7322 | all | phecode |
| 803.2 | Fracture of radius and ulna | Injuries & Poisonings | 0.982 | 0.923 – 1.05 | 0.581 | 1112 | 11075 | all | phecode |
| 803.21 | Colles' fracture | Injuries & Poisonings | 0.919 | 0.813 – 1.04 | 0.178 | 291 | 2904 | all | phecode |
| 803.3 | Fracture of clavicle or scapula | Injuries & Poisonings | 1.05 | 0.96 – 1.15 | 0.281 | 514 | 5140 | all | phecode |
| 804 | Fracture of hand or wrist | Injuries & Poisonings | 1 | 0.953 – 1.06 | 0.898 | 1628 | 16042 | all | phecode |
| 805 |
Fracture of vertebral column without mention ofFracture of vertebral column without mention of spinal cord injury
|
Injuries & Poisonings | 0.95 | 0.897 – 1.01 | 0.0759 | 1336 | 13242 | all | phecode |
| 807 | Fracture of ribs | Injuries & Poisonings | 0.992 | 0.917 – 1.07 | 0.843 | 683 | 6815 | all | phecode |
| 809 | Fracture of unspecified bones | Injuries & Poisonings | 1.01 | 0.971 – 1.05 | 0.639 | 2941 | 28633 | all | phecode |
| 816 | Cerebral laceration and contusion | Injuries & Poisonings | 0.866 | 0.655 – 1.14 | 0.311 | 54 | 531 | all | phecode |
| 817 | Concussion | Injuries & Poisonings | 0.985 | 0.922 – 1.05 | 0.642 | 1018 | 10149 | all | phecode |
| 818 | Intracranial hemorrhage (injury) | Injuries & Poisonings | 0.975 | 0.869 – 1.09 | 0.672 | 311 | 3104 | all | phecode |
| 818.1 | Subdural hemorrhage (injury) | Injuries & Poisonings | 0.993 | 0.804 – 1.22 | 0.944 | 90 | 895 | all | phecode |
| 818.2 | Subarachnoid hemorrhage (injury) | Injuries & Poisonings | 0.944 | 0.768 – 1.16 | 0.581 | 97 | 970 | all | phecode |
| 819 |
Skull and face fracture and other intercranialSkull and face fracture and other intercranial injury
|
Injuries & Poisonings | 0.985 | 0.943 – 1.03 | 0.49 | 2287 | 22671 | all | phecode |
| 830 | Dislocation | Injuries & Poisonings | 1.02 | 0.983 – 1.05 | 0.341 | 3862 | 34720 | all | phecode |
| 835 | Internal derangement of knee | Injuries & Poisonings | 1 | 0.957 – 1.05 | 0.995 | 2231 | 21628 | all | phecode |
| 836 | Traumatic arthropathy | Injuries & Poisonings | 1.05 | 0.955 – 1.15 | 0.32 | 496 | 4954 | all | phecode |
| 840 | Sprains and strains | Injuries & Poisonings | 0.993 | 0.968 – 1.02 | 0.566 | 7838 | 37998 | all | phecode |
| 840.1 | Muscle/tendon sprain | Injuries & Poisonings | 1.08 | 0.99 – 1.19 | 0.0796 | 537 | 5356 | all | phecode |
| 840.2 | Rotator cuff (capsule) sprain | Injuries & Poisonings | 1.03 | 0.982 – 1.09 | 0.202 | 1640 | 16263 | all | phecode |
| 840.3 | Joint/ligament sprain | Injuries & Poisonings | 0.983 | 0.945 – 1.02 | 0.396 | 2875 | 24879 | all | phecode |
| 841 | Sprains and strains of back and neck | Injuries & Poisonings | 0.98 | 0.93 – 1.03 | 0.442 | 1583 | 15592 | all | phecode |
| 842 | Other sprains and strains | Injuries & Poisonings | 0.982 | 0.929 – 1.04 | 0.531 | 1407 | 13924 | all | phecode |
| 850 | Hemorrhage or hematoma complicating a procedure | Injuries & Poisonings | 0.981 | 0.937 – 1.03 | 0.421 | 2072 | 20649 | all | phecode |
| 851 |
Complications of transplants and reattachedComplications of transplants and reattached limbs
|
Injuries & Poisonings | 0.995 | 0.958 – 1.03 | 0.815 | 2982 | 27545 | all | phecode |
| 853 | Complication of colostomy or enterostomy | Injuries & Poisonings | 0.94 | 0.853 – 1.04 | 0.215 | 460 | 4600 | all | phecode |
| 854 |
Complications of cardiac/vascular deviceComplications of cardiac/vascular device, implant, and graft
|
Injuries & Poisonings | 1 | 0.955 – 1.05 | 0.983 | 1985 | 19675 | all | phecode |
| 855 |
Complication of nervous system device, implantComplication of nervous system device, implant, and graft
|
Injuries & Poisonings | 0.98 | 0.864 – 1.11 | 0.758 | 264 | 2640 | all | phecode |
| 856 |
Vascular complications of surgery and medicalVascular complications of surgery and medical procedures
|
Injuries & Poisonings | 0.929 | 0.822 – 1.05 | 0.242 | 293 | 2929 | all | phecode |
| 857 |
Mechanical complication of unspecifiedMechanical complication of unspecified genitourinary device, implant, and graft
|
Injuries & Poisonings | 1.03 | 0.969 – 1.09 | 0.38 | 1310 | 13087 | all | phecode |
| 858 | Complication of internal orthopedic device | Injuries & Poisonings | 0.981 | 0.939 – 1.03 | 0.409 | 2213 | 21944 | all | phecode |
| 859 |
Complication due to other implant and internalComplication due to other implant and internal device
|
Injuries & Poisonings | 1 | 0.959 – 1.05 | 0.89 | 2110 | 21070 | all | phecode |
| 860 | Bone marrow or stem cell transplant | Neoplasms | 0.879 | 0.75 – 1.03 | 0.113 | 166 | 1660 | all | phecode |
| 870 | Open wounds of head; neck; and trunk | Injuries & Poisonings | 1.02 | 0.989 – 1.06 | 0.196 | 4117 | 36734 | all | phecode |
| 870.1 | Open wound or laceration of eye or eyelid | Injuries & Poisonings | 1.06 | 0.919 – 1.22 | 0.423 | 204 | 2026 | all | phecode |
| 870.2 | Open wound of ear | Injuries & Poisonings | 0.99 | 0.832 – 1.18 | 0.906 | 144 | 1437 | all | phecode |
| 870.3 | Other open wound of head and face | Injuries & Poisonings | 1.05 | 0.992 – 1.11 | 0.0928 | 1346 | 13301 | all | phecode |
| 870.4 | Open wound of nose and sinus | Injuries & Poisonings | 1.02 | 0.887 – 1.17 | 0.793 | 207 | 2057 | all | phecode |
| 870.5 | Open wound of lip and mouth | Injuries & Poisonings | 1.08 | 0.96 – 1.23 | 0.19 | 275 | 2724 | all | phecode |
| 870.6 | Open wound of neck | Injuries & Poisonings | 1.03 | 0.894 – 1.19 | 0.683 | 214 | 2128 | all | phecode |
| 870.8 | Open wound of genital organs | Injuries & Poisonings | 0.942 | 0.796 – 1.11 | 0.488 | 144 | 1440 | all | phecode |
| 871 | Open wounds of extremities | Injuries & Poisonings | 1.04 | 1 – 1.07 | 0.049 | 3530 | 32903 | all | phecode |
| 871.1 | Open wound of hand except finger(s) | Injuries & Poisonings | 1 | 0.921 – 1.1 | 0.92 | 572 | 5701 | all | phecode |
| 871.2 | Open wound of finger(s) | Injuries & Poisonings | 1.01 | 0.947 – 1.08 | 0.728 | 984 | 9772 | all | phecode |
| 871.3 | Open wound of foot except toe(s) alone | Injuries & Poisonings | 1.09 | 0.995 – 1.2 | 0.0642 | 490 | 4843 | all | phecode |
| 871.4 | Open wound of toe(s) | Injuries & Poisonings | 1.06 | 0.942 – 1.2 | 0.318 | 295 | 2921 | all | phecode |
| 872 | Traumatic amputation | Injuries & Poisonings | 1.05 | 0.957 – 1.14 | 0.325 | 551 | 5477 | all | phecode |
| 874 | Complication of amputation stump | Injuries & Poisonings | 0.97 | 0.834 – 1.13 | 0.697 | 170 | 1697 | all | phecode |
| 875 | Non-healing surgical wound | Injuries & Poisonings | 1.03 | 0.945 – 1.12 | 0.503 | 572 | 5720 | all | phecode |
| 876 |
Posttraumatic wound infection not elsewherePosttraumatic wound infection not elsewhere classified
|
Injuries & Poisonings | 1.01 | 0.941 – 1.09 | 0.76 | 802 | 8003 | all | phecode |
| 907 | Injuries to the nervous system | Injuries & Poisonings | 1.06 | 0.991 – 1.13 | 0.0918 | 1010 | 10096 | all | phecode |
| 910 | Superficial injury, infected | Injuries & Poisonings | 0.922 | 0.764 – 1.11 | 0.398 | 119 | 1161 | all | phecode |
| 911 | Blister | Injuries & Poisonings | 1.18 | 1.05 – 1.32 | 0.00649 | 302 | 2996 | all | phecode |
| 912 | Insect bite | Injuries & Poisonings | 0.979 | 0.891 – 1.08 | 0.659 | 492 | 4886 | all | phecode |
| 913 | Toxic effect of venom | Injuries & Poisonings | 0.968 | 0.864 – 1.08 | 0.57 | 337 | 3326 | all | phecode |
| 916 | Contusion | Injuries & Poisonings | 0.995 | 0.964 – 1.03 | 0.779 | 4296 | 38033 | all | phecode |
| 930 | Allergic reaction to food | Injuries & Poisonings | 0.947 | 0.879 – 1.02 | 0.151 | 763 | 7596 | all | phecode |
| 931 |
Contact dermatitis and other eczema due toContact dermatitis and other eczema due to plants [except food]
|
Dermatologic | 0.952 | 0.879 – 1.03 | 0.224 | 714 | 7072 | all | phecode |
| 938 | Dermatitis due to solar radiation | Dermatologic | 0.982 | 0.954 – 1.01 | 0.232 | 5567 | 29098 | all | phecode |
| 938.1 | Acute dermatitis due to solar radiation | Dermatologic | 1.03 | 0.899 – 1.19 | 0.643 | 217 | 2164 | all | phecode |
| 938.2 | Chronic dermatitis due to solar radiation | Dermatologic | 0.98 | 0.951 – 1.01 | 0.185 | 5307 | 28656 | all | phecode |
| 939 |
Atopic/contact dermatitis due to other orAtopic/contact dermatitis due to other or unspecified
|
Dermatologic | 0.991 | 0.965 – 1.02 | 0.525 | 6704 | 32389 | all | phecode |
| 939.1 | Contact and allergic dermatitis of eyelid | Dermatologic | 1.15 | 0.938 – 1.41 | 0.179 | 91 | 870 | all | phecode |
| 941 | Adverse reaction to serum or vaccine | Injuries & Poisonings | 1.09 | 0.939 – 1.27 | 0.256 | 188 | 1880 | all | phecode |
| 942 | Infusion and transfusion reaction | Injuries & Poisonings | 0.973 | 0.859 – 1.1 | 0.665 | 269 | 2688 | all | phecode |
| 946 | Anaphylactic shock NOS | Injuries & Poisonings | 0.904 | 0.824 – 0.991 | 0.0322 | 500 | 4940 | all | phecode |
| 947 | Urticaria | Dermatologic | 1.02 | 0.959 – 1.08 | 0.552 | 1177 | 11454 | all | phecode |
| 949 | Allergies, other | Injuries & Poisonings | 0.973 | 0.948 – 0.999 | 0.043 | 7251 | 32350 | all | phecode |
| 952 |
Spinal cord injury without evidence of spinalSpinal cord injury without evidence of spinal bone injury
|
Injuries & Poisonings | 1.1 | 1.01 – 1.21 | 0.0355 | 494 | 4940 | all | phecode |
| 957 | Injury to other and unspecified nerves | Injuries & Poisonings | 1.17 | 0.979 – 1.4 | 0.0844 | 136 | 1352 | all | phecode |
| 958 |
Certain early complications of trauma orCertain early complications of trauma or procedure
|
Injuries & Poisonings | 1.01 | 0.952 – 1.07 | 0.74 | 1217 | 12158 | all | phecode |
| 958.1 | Postoperative shock | Injuries & Poisonings | 0.988 | 0.843 – 1.16 | 0.885 | 169 | 1688 | all | phecode |
| 958.2 | Traumatic and surgical subcutaneous emphysema | Injuries & Poisonings | 1.21 | 0.998 – 1.47 | 0.052 | 114 | 1140 | all | phecode |
| 960 | Poisoning by antibiotics | Injuries & Poisonings | 1.02 | 0.981 – 1.07 | 0.283 | 2479 | 22087 | all | phecode |
| 960.1 |
Adverse effects of antibacterials (notAdverse effects of antibacterials (not penicillins)
|
Injuries & Poisonings | 0.912 | 0.816 – 1.02 | 0.107 | 342 | 3403 | all | phecode |
| 960.2 | Allergy/adverse effect of penicillin | Injuries & Poisonings | 1.02 | 0.971 – 1.08 | 0.39 | 1636 | 16005 | all | phecode |
| 961 | Poisoning by other anti-infectives | Injuries & Poisonings | 0.942 | 0.861 – 1.03 | 0.194 | 528 | 5234 | all | phecode |
| 961.1 | Poisoning/allergy of sulfonamides | Injuries & Poisonings | 1.02 | 0.96 – 1.09 | 0.479 | 1065 | 10347 | all | phecode |
| 962 | Poisoning by hormones and synthetic substitutes | Injuries & Poisonings | 1.06 | 0.984 – 1.14 | 0.126 | 803 | 7976 | all | phecode |
| 962.1 |
Adrenal cortical steroids causing adverseAdrenal cortical steroids causing adverse effects in therapeutic use
|
Injuries & Poisonings | 0.987 | 0.887 – 1.1 | 0.809 | 379 | 3782 | all | phecode |
| 962.2 |
Insulins and antidiabetic agents causingInsulins and antidiabetic agents causing adverse effects in therapeutic use
|
Injuries & Poisonings | 1.14 | 0.875 – 1.5 | 0.325 | 62 | 612 | all | phecode |
| 962.3 |
Hormones and synthetic substitutes causingHormones and synthetic substitutes causing adverse effects in therapeutic use
|
Injuries & Poisonings | 1.11 | 1.01 – 1.22 | 0.031 | 478 | 4773 | all | phecode |
| 963 | Poisoning by primarily systemic agents | Injuries & Poisonings | 0.975 | 0.935 – 1.02 | 0.228 | 2533 | 24531 | all | phecode |
| 963.1 |
Antineoplastic and immunosuppressive drugsAntineoplastic and immunosuppressive drugs causing adverse effects
|
Injuries & Poisonings | 0.974 | 0.933 – 1.02 | 0.216 | 2469 | 24057 | all | phecode |
| 964 |
Poisoning by agents primarily affecting bloodPoisoning by agents primarily affecting blood constituents
|
Injuries & Poisonings | 0.977 | 0.906 – 1.05 | 0.543 | 743 | 7337 | all | phecode |
| 964.1 | Anticoagulants causing adverse effects | Injuries & Poisonings | 0.98 | 0.907 – 1.06 | 0.601 | 712 | 7027 | all | phecode |
| 965 |
Poisoning by analgesics, antipyretics, andPoisoning by analgesics, antipyretics, and antirheumatics
|
Injuries & Poisonings | 1.03 | 0.959 – 1.1 | 0.427 | 864 | 8601 | all | phecode |
| 965.1 |
Opiates and related narcotics causing adverseOpiates and related narcotics causing adverse effects in therapeutic use
|
Injuries & Poisonings | 1.05 | 0.99 – 1.1 | 0.112 | 1469 | 14402 | all | phecode |
| 965.3 |
Salicylates causing adverse effects inSalicylates causing adverse effects in therapeutic use
|
Injuries & Poisonings | 1.1 | 0.91 – 1.32 | 0.33 | 119 | 1182 | all | phecode |
| 966 |
Poisoning by anticonvulsants andPoisoning by anticonvulsants and anti-Parkinsonism drugs
|
Injuries & Poisonings | 1.08 | 0.877 – 1.34 | 0.455 | 103 | 1006 | all | phecode |
| 967 |
Adverse effects of sedatives or other centralAdverse effects of sedatives or other central nervous system depressants and anesthetics
|
Injuries & Poisonings | 0.983 | 0.927 – 1.04 | 0.557 | 1254 | 12464 | all | phecode |
| 969 | Poisoning by psychotropic agents | Injuries & Poisonings | 1.18 | 1.04 – 1.34 | 0.0103 | 281 | 2797 | all | phecode |
| 971 |
Poisoning by drugs primarily affecting thePoisoning by drugs primarily affecting the autonomic nervous system
|
Injuries & Poisonings | 1.11 | 0.861 – 1.42 | 0.426 | 67 | 643 | all | phecode |
| 972 |
Poisoning by agents primarily affecting thePoisoning by agents primarily affecting the cardiovascular system
|
Injuries & Poisonings | 1.17 | 1.03 – 1.33 | 0.0125 | 288 | 2858 | all | phecode |
| 972.1 |
Cardiac rhythm regulators causing adverseCardiac rhythm regulators causing adverse effects in therapeutic use
|
Injuries & Poisonings | 1.36 | 1.08 – 1.72 | 0.0087 | 80 | 776 | all | phecode |
| 972.6 | Antihypertensive agents causing adverse effects | Injuries & Poisonings | 1.02 | 0.837 – 1.24 | 0.864 | 104 | 1034 | all | phecode |
| 974 |
Poisoning by water, mineral, and uric acidPoisoning by water, mineral, and uric acid metabolism drugs
|
Injuries & Poisonings | 1.06 | 0.879 – 1.29 | 0.529 | 113 | 1130 | all | phecode |
| 975 |
Poisoning by agents primarily acting on thePoisoning by agents primarily acting on the smooth and skeletal muscles and respiratory system
|
Injuries & Poisonings | 1.03 | 0.813 – 1.3 | 0.812 | 81 | 810 | all | phecode |
| 976 |
Poisoning by agents primarily affecting skin &Poisoning by agents primarily affecting skin & mucous membrane, ophthalmological, otorhinolaryngological, & dental drugs
|
Injuries & Poisonings | 1.08 | 0.848 – 1.37 | 0.535 | 71 | 703 | all | phecode |
| 977 | Personal history of allergy to medicinal agents | Injuries & Poisonings | 1.01 | 0.965 – 1.07 | 0.569 | 1763 | 16599 | all | phecode |
| 979 | Adverse drug events and drug allergies | Injuries & Poisonings | 1.01 | 0.973 – 1.05 | 0.633 | 3448 | 30885 | all | phecode |
| 980 |
Encounter for long-term (current) use ofEncounter for long-term (current) use of antibiotics
|
Infectious Diseases | 1.02 | 0.968 – 1.08 | 0.416 | 1391 | 13877 | all | phecode |
| 985 | Toxic effect of other metals | Injuries & Poisonings | 1.15 | 0.88 – 1.5 | 0.307 | 57 | 564 | all | phecode |
| 989 |
Toxic effect of other substances, chieflyToxic effect of other substances, chiefly nonmedicinal as to source
|
Injuries & Poisonings | 1.16 | 0.965 – 1.39 | 0.114 | 129 | 1275 | all | phecode |
| 990 | Effects radiation NOS | Injuries & Poisonings | 1.01 | 0.98 – 1.05 | 0.426 | 3927 | 31223 | all | phecode |
| 994 | Sepsis and SIRS | Injuries & Poisonings | 1.05 | 1 – 1.1 | 0.0299 | 2192 | 21710 | all | phecode |
| 994.1 | Systemic inflammatory response syndrome (SIRS) | Injuries & Poisonings | 1.06 | 0.94 – 1.19 | 0.344 | 291 | 2910 | all | phecode |
| 994.2 | Sepsis | Injuries & Poisonings | 1.05 | 1 – 1.1 | 0.0365 | 2086 | 20666 | all | phecode |
| 994.21 | Septic shock | Injuries & Poisonings | 1.04 | 0.958 – 1.13 | 0.342 | 627 | 6260 | all | phecode |
| 008 | Intestinal infection | Infectious Diseases | 1 | 0.952 – 1.06 | 0.866 | 1500 | 14999 | exclusion | phecode |
| 008.5 | Bacterial enteritis | Infectious Diseases | 1.02 | 0.936 – 1.11 | 0.666 | 605 | 6519 | exclusion | phecode |
| 008.52 | Intestinal infection due to C. difficile | Infectious Diseases | 1.02 | 0.925 – 1.12 | 0.717 | 471 | 5167 | exclusion | phecode |
| 008.6 | Viral Enteritis | Infectious Diseases | 1.05 | 0.946 – 1.17 | 0.344 | 384 | 3932 | exclusion | phecode |
| 010 | Tuberculosis | Infectious Diseases | 1.11 | 0.907 – 1.37 | 0.302 | 106 | 1220 | exclusion | phecode |
| 031 | Diseases due to other mycobacteria | Infectious Diseases | 1.29 | 0.941 – 1.76 | 0.115 | 42 | 450 | exclusion | phecode |
| 038 | Septicemia | Infectious Diseases | 1.04 | 0.973 – 1.1 | 0.272 | 1074 | 11878 | exclusion | phecode |
| 038.1 | Gram negative septicemia | Infectious Diseases | 1.06 | 0.933 – 1.21 | 0.358 | 246 | 2622 | exclusion | phecode |
| 038.2 | Gram positive septicemia | Infectious Diseases | 1.34 | 1.06 – 1.68 | 0.0129 | 79 | 1100 | exclusion | phecode |
| 038.3 | Bacteremia | Infectious Diseases | 1.06 | 0.966 – 1.16 | 0.226 | 505 | 5676 | exclusion | phecode |
| 041 | Bacterial infection NOS | Infectious Diseases | 1.01 | 0.971 – 1.06 | 0.572 | 2595 | 19884 | exclusion | phecode |
| 041.1 | Staphylococcus infections | Infectious Diseases | 0.961 | 0.89 – 1.04 | 0.304 | 739 | 8376 | exclusion | phecode |
| 041.11 | Methicillin sensitive Staphylococcus aureus | Infectious Diseases | 0.977 | 0.881 – 1.08 | 0.665 | 403 | 4495 | exclusion | phecode |
| 041.12 | Methicillin resistant Staphylococcus aureus | Infectious Diseases | 0.97 | 0.867 – 1.09 | 0.599 | 339 | 3937 | exclusion | phecode |
| 041.2 | Streptococcus infection | Infectious Diseases | 1.04 | 0.962 – 1.12 | 0.333 | 729 | 7921 | exclusion | phecode |
| 041.21 | Rheumatic fever / chorea | Infectious Diseases | 1.08 | 0.89 – 1.31 | 0.439 | 111 | 1255 | exclusion | phecode |
| 041.4 | E. coli | Infectious Diseases | 1.07 | 0.983 – 1.17 | 0.115 | 537 | 5867 | exclusion | phecode |
| 041.8 | H. pylori | Infectious Diseases | 1.04 | 0.859 – 1.26 | 0.675 | 113 | 1289 | exclusion | phecode |
| 041.9 | Infection with drug-resistant microorganisms | Infectious Diseases | 0.983 | 0.839 – 1.15 | 0.829 | 165 | 1900 | exclusion | phecode |
| 053 | Herpes zoster | Infectious Diseases | 0.991 | 0.921 – 1.07 | 0.811 | 809 | 7398 | exclusion | phecode |
| 053.1 | Herpes zoster with nervous system complications | Infectious Diseases | 1.03 | 0.843 – 1.26 | 0.773 | 108 | 1045 | exclusion | phecode |
| 054 | Herpes simplex | Infectious Diseases | 1.05 | 0.972 – 1.13 | 0.229 | 821 | 8089 | exclusion | phecode |
| 070 | Viral hepatitis | Infectious Diseases | 1.11 | 0.982 – 1.26 | 0.0941 | 270 | 3958 | exclusion | phecode |
| 070.1 | Viral hepatitis A | Infectious Diseases | 0.961 | 0.709 – 1.3 | 0.797 | 46 | 399 | exclusion | phecode |
| 070.2 | Viral hepatitis B | Infectious Diseases | 1 | 0.804 – 1.25 | 0.986 | 86 | 1022 | exclusion | phecode |
| 070.3 | Viral hepatitis C | Infectious Diseases | 1.23 | 1.02 – 1.48 | 0.0306 | 122 | 2488 | exclusion | phecode |
| 070.4 | Chronic hepatitis | Infectious Diseases | 0.905 | 0.717 – 1.14 | 0.401 | 81 | 943 | exclusion | phecode |
| 070.9 | Hepatitis NOS | Infectious Diseases | 1.05 | 0.955 – 1.16 | 0.302 | 455 | 5322 | exclusion | phecode |
| 071 | Human immunodeficiency virus [HIV] disease | Infectious Diseases | 1.11 | 0.84 – 1.47 | 0.457 | 53 | 747 | exclusion | phecode |
| 071.1 | HIV infection, symptomatic | Infectious Diseases | 1.05 | 0.778 – 1.42 | 0.751 | 43 | 611 | exclusion | phecode |
| 078 | Viral warts & HPV | Infectious Diseases | 1.02 | 0.976 – 1.08 | 0.329 | 1859 | 15326 | exclusion | phecode |
| 079 | Viral infection | Infectious Diseases | 1 | 0.968 – 1.04 | 0.835 | 3647 | 17795 | exclusion | phecode |
| 079.1 | Varicella infection | Infectious Diseases | 1.01 | 0.967 – 1.06 | 0.599 | 2098 | 15567 | exclusion | phecode |
| 079.2 | Infectious mononucleosis | Infectious Diseases | 1.16 | 0.994 – 1.35 | 0.0588 | 185 | 1661 | exclusion | phecode |
| 079.9 | Viremia, NOS | Infectious Diseases | 1.08 | 0.978 – 1.19 | 0.132 | 467 | 4394 | exclusion | phecode |
| 080 | Postoperative infection | Infectious Diseases | 1 | 0.942 – 1.06 | 0.97 | 1146 | 12894 | exclusion | phecode |
| 081 |
Infection/inflammation of internal prostheticInfection/inflammation of internal prosthetic device; implant; and graft
|
Infectious Diseases | 0.958 | 0.885 – 1.04 | 0.284 | 679 | 7690 | exclusion | phecode |
| 090 |
Sexually transmitted infections (not HIV orSexually transmitted infections (not HIV or hepatitis)
|
Infectious Diseases | 1.06 | 0.96 – 1.17 | 0.258 | 457 | 5148 | exclusion | phecode |
| 110 | Dermatophytosis / Dermatomycosis | Infectious Diseases | 1.02 | 0.972 – 1.07 | 0.392 | 1808 | 14833 | exclusion | phecode |
| 110.1 | Dermatophytosis | Infectious Diseases | 1.01 | 0.961 – 1.07 | 0.634 | 1661 | 13348 | exclusion | phecode |
| 110.11 | Dermatophytosis of nail | Infectious Diseases | 1.02 | 0.954 – 1.09 | 0.556 | 999 | 8134 | exclusion | phecode |
| 110.12 | Althete's foot | Infectious Diseases | 0.98 | 0.889 – 1.08 | 0.685 | 467 | 3866 | exclusion | phecode |
| 110.13 | Dermatophytosis of the body | Infectious Diseases | 0.963 | 0.87 – 1.07 | 0.464 | 432 | 3888 | exclusion | phecode |
| 110.2 | Dermatomycoses | Infectious Diseases | 1.09 | 0.941 – 1.25 | 0.26 | 203 | 2062 | exclusion | phecode |
| 112 | Candidiasis | Infectious Diseases | 0.998 | 0.95 – 1.05 | 0.948 | 1817 | 15772 | exclusion | phecode |
| 112.3 | Candidiasis of skin and nails | Infectious Diseases | 1.05 | 0.933 – 1.17 | 0.445 | 337 | 3418 | exclusion | phecode |
| 117 | Mycoses | Infectious Diseases | 0.931 | 0.824 – 1.05 | 0.247 | 288 | 3024 | exclusion | phecode |
| 117.1 | Histoplasmosis | Infectious Diseases | 1.13 | 0.798 – 1.59 | 0.496 | 31 | 405 | exclusion | phecode |
| 117.4 | Aspergillosis | Infectious Diseases | 0.849 | 0.657 – 1.1 | 0.211 | 62 | 709 | exclusion | phecode |
| 130 | Spirochetal infection | Infectious Diseases | 1.14 | 0.921 – 1.41 | 0.229 | 99 | 856 | exclusion | phecode |
| 130.1 | Lyme disease | Infectious Diseases | 1.01 | 0.787 – 1.29 | 0.95 | 69 | 588 | exclusion | phecode |
| 131 | Protozoan infection | Infectious Diseases | 1.06 | 0.737 – 1.54 | 0.739 | 29 | 328 | exclusion | phecode |
| 132 | Infestation (lice, mites) | Infectious Diseases | 1.03 | 0.835 – 1.27 | 0.78 | 92 | 946 | exclusion | phecode |
| 134 | Helminthiases | Infectious Diseases | 1.13 | 0.85 – 1.5 | 0.4 | 54 | 397 | exclusion | phecode |
| 134.1 | Intestinal helminthiases | Infectious Diseases | 1.12 | 0.785 – 1.61 | 0.526 | 34 | 263 | exclusion | phecode |
| 136 | Other infectious and parasitic diseases | Infectious Diseases | 1.03 | 0.976 – 1.09 | 0.28 | 1528 | 16347 | exclusion | phecode |
| 145 | Cancer of mouth | Neoplasms | 0.952 | 0.872 – 1.04 | 0.268 | 536 | 6747 | exclusion | phecode |
| 145.1 | Cancer of lip | Neoplasms | 0.924 | 0.643 – 1.33 | 0.672 | 29 | 331 | exclusion | phecode |
| 145.2 | Cancer of tongue | Neoplasms | 0.958 | 0.835 – 1.1 | 0.543 | 214 | 2989 | exclusion | phecode |
| 145.3 | Cancer of major salivary glands | Neoplasms | 0.993 | 0.847 – 1.16 | 0.931 | 165 | 1628 | exclusion | phecode |
| 145.4 | Cancer of the gums | Neoplasms | 0.863 | 0.683 – 1.09 | 0.215 | 77 | 738 | exclusion | phecode |
| 145.5 | Cancer of the mouth floor | Neoplasms | 0.9 | 0.666 – 1.22 | 0.494 | 41 | 958 | exclusion | phecode |
| 149 | Cancer of larynx, pharynx, nasal cavities | Neoplasms | 0.983 | 0.89 – 1.09 | 0.743 | 416 | 5849 | exclusion | phecode |
| 149.1 | Cancer of oropharynx | Neoplasms | 0.859 | 0.708 – 1.04 | 0.122 | 114 | 1600 | exclusion | phecode |
| 149.2 | Cancer of nasopharynx | Neoplasms | 1.25 | 0.934 – 1.68 | 0.133 | 46 | 483 | exclusion | phecode |
| 149.3 | Cancer of hypopharynx | Neoplasms | 1.6 | 1 – 2.56 | 0.0483 | 16 | 379 | exclusion | phecode |
| 149.4 | Cancer of larynx | Neoplasms | 1.09 | 0.852 – 1.41 | 0.481 | 61 | 1678 | exclusion | phecode |
| 149.5 |
Hx of malignant neoplasm of oral cavity andHx of malignant neoplasm of oral cavity and pharynx
|
Neoplasms | 0.957 | 0.825 – 1.11 | 0.565 | 187 | 2444 | exclusion | phecode |
| 149.9 | Cancer of of nasal cavities | Neoplasms | 0.999 | 0.811 – 1.23 | 0.991 | 96 | 1141 | exclusion | phecode |
| 150 | Cancer of esophagus | Neoplasms | 0.988 | 0.826 – 1.18 | 0.898 | 119 | 1925 | exclusion | phecode |
| 151 | Cancer of stomach | Neoplasms | 0.984 | 0.845 – 1.14 | 0.83 | 177 | 2200 | exclusion | phecode |
| 153 | Colorectal cancer | Neoplasms | 0.991 | 0.912 – 1.08 | 0.823 | 631 | 6757 | exclusion | phecode |
| 153.2 | Colon cancer | Neoplasms | 1.02 | 0.927 – 1.11 | 0.727 | 510 | 5352 | exclusion | phecode |
| 153.3 |
Malignant neoplasm of rectum, rectosigmoidMalignant neoplasm of rectum, rectosigmoid junction, and anus
|
Neoplasms | 0.991 | 0.887 – 1.11 | 0.879 | 352 | 3915 | exclusion | phecode |
| 155 | Cancer of liver and intrahepatic bile duct | Neoplasms | 0.964 | 0.834 – 1.11 | 0.619 | 201 | 2380 | exclusion | phecode |
| 155.1 | Malignant neoplasm of liver, primary | Neoplasms | 0.977 | 0.813 – 1.17 | 0.801 | 124 | 1601 | exclusion | phecode |
| 157 | Pancreatic cancer | Neoplasms | 0.958 | 0.833 – 1.1 | 0.552 | 230 | 2307 | exclusion | phecode |
| 158 |
Neoplasm of unspecified nature of digestiveNeoplasm of unspecified nature of digestive system
|
Neoplasms | 0.958 | 0.887 – 1.03 | 0.274 | 727 | 7485 | exclusion | phecode |
| 159 |
Malignant neoplasm of other and ill-definedMalignant neoplasm of other and ill-defined sites within the digestive organs and peritoneum
|
Neoplasms | 0.976 | 0.907 – 1.05 | 0.526 | 792 | 8406 | exclusion | phecode |
| 159.2 |
Malignant neoplasm of small intestineMalignant neoplasm of small intestine, including duodenum
|
Neoplasms | 0.946 | 0.775 – 1.15 | 0.581 | 99 | 1045 | exclusion | phecode |
| 159.3 |
Malignant neoplasm of gallbladder andMalignant neoplasm of gallbladder and extrahepatic bile ducts
|
Neoplasms | 0.939 | 0.728 – 1.21 | 0.625 | 67 | 719 | exclusion | phecode |
| 159.4 |
Malignant neoplasm of retroperitoneum andMalignant neoplasm of retroperitoneum and peritoneum
|
Neoplasms | 1.09 | 0.918 – 1.29 | 0.332 | 148 | 1461 | exclusion | phecode |
| 164 | Cancer of intrathoracic organs | Neoplasms | 0.96 | 0.751 – 1.23 | 0.742 | 69 | 604 | exclusion | phecode |
| 165 | Cancer within the respiratory system | Neoplasms | 0.954 | 0.854 – 1.07 | 0.399 | 345 | 6037 | exclusion | phecode |
| 165.1 | Cancer of bronchus; lung | Neoplasms | 0.931 | 0.822 – 1.05 | 0.26 | 272 | 4813 | exclusion | phecode |
| 170 | Cancer of bone and connective tissue | Neoplasms | 0.944 | 0.878 – 1.01 | 0.118 | 836 | 8307 | exclusion | phecode |
| 170.1 | Bone cancer | Neoplasms | 0.942 | 0.845 – 1.05 | 0.29 | 359 | 3583 | exclusion | phecode |
| 170.2 | Cancer of connective tissue | Neoplasms | 0.938 | 0.861 – 1.02 | 0.147 | 607 | 5937 | exclusion | phecode |
| 172 | Skin cancer | Neoplasms | 0.994 | 0.958 – 1.03 | 0.733 | 4051 | 16273 | exclusion | phecode |
| 172.1 | Melanomas of skin, dx or hx | Neoplasms | 0.993 | 0.951 – 1.04 | 0.751 | 2628 | 14503 | exclusion | phecode |
| 172.11 | Melanomas of skin | Neoplasms | 0.989 | 0.938 – 1.04 | 0.7 | 1542 | 11840 | exclusion | phecode |
| 172.2 | Other non-epithelial cancer of skin | Neoplasms | 0.994 | 0.956 – 1.03 | 0.783 | 3288 | 14713 | exclusion | phecode |
| 172.21 | Basal cell carcinoma | Neoplasms | 1 | 0.951 – 1.05 | 0.994 | 1827 | 11125 | exclusion | phecode |
| 172.22 | Squamous cell carcinoma | Neoplasms | 0.956 | 0.893 – 1.02 | 0.2 | 950 | 7876 | exclusion | phecode |
| 172.3 | Carcinoma in situ of skin | Neoplasms | 0.962 | 0.89 – 1.04 | 0.323 | 720 | 5506 | exclusion | phecode |
| 173 | Neoplasm of uncertain behavior of skin | Neoplasms | 1.03 | 0.963 – 1.09 | 0.421 | 1056 | 9048 | exclusion | phecode |
| 174 | Breast cancer | Neoplasms | 0.986 | 0.936 – 1.04 | 0.602 | 1817 | 8197 | exclusion | phecode |
| 174.1 | Breast cancer [female] | Neoplasms | 0.99 | 0.938 – 1.05 | 0.722 | 1735 | 7835 | exclusion | phecode |
| 174.11 | Malignant neoplasm of female breast | Neoplasms | 0.99 | 0.938 – 1.04 | 0.714 | 1711 | 7800 | exclusion | phecode |
| 174.3 | Neoplasm of uncertain behavior of breast | Neoplasms | 0.898 | 0.753 – 1.07 | 0.23 | 135 | 1211 | exclusion | phecode |
| 175 | Acquired absence of breast | Neoplasms | 0.89 | 0.81 – 0.979 | 0.0161 | 513 | 4632 | exclusion | phecode |
| 180 | Cervical cancer and dysplasia | Neoplasms | 0.987 | 0.908 – 1.07 | 0.754 | 633 | 6556 | exclusion | phecode |
| 180.1 | Cervical cancer | Neoplasms | 0.931 | 0.801 – 1.08 | 0.348 | 183 | 2600 | exclusion | phecode |
| 180.3 |
Cervical intraepithelial neoplasia [CIN]Cervical intraepithelial neoplasia [CIN] [Cervical dysplasia]
|
Neoplasms | 1.03 | 0.938 – 1.13 | 0.529 | 496 | 5043 | exclusion | phecode |
| 182 | Malignant neoplasm of uterus | Neoplasms | 0.955 | 0.865 – 1.06 | 0.368 | 446 | 3836 | exclusion | phecode |
| 184 | Cancer of other female genital organs | Neoplasms | 0.969 | 0.888 – 1.06 | 0.482 | 576 | 6072 | exclusion | phecode |
| 184.1 |
Malignant neoplasm of ovary and other uterineMalignant neoplasm of ovary and other uterine adnexa
|
Neoplasms | 0.984 | 0.874 – 1.11 | 0.786 | 310 | 2947 | exclusion | phecode |
| 184.11 | Malignant neoplasm of ovary | Neoplasms | 0.959 | 0.839 – 1.1 | 0.541 | 243 | 2201 | exclusion | phecode |
| 184.2 |
Cancer of other female genital organsCancer of other female genital organs (excluding uterus and ovary)
|
Neoplasms | 0.981 | 0.869 – 1.11 | 0.758 | 281 | 3187 | exclusion | phecode |
| 185 | Cancer of prostate | Neoplasms | 0.988 | 0.922 – 1.06 | 0.739 | 1167 | 4283 | exclusion | phecode |
| 187 | Cancer of other male genital organs | Neoplasms | 1.05 | 0.883 – 1.25 | 0.578 | 150 | 1460 | exclusion | phecode |
| 187.1 |
Malignant neoplasm of unspecified male genitalMalignant neoplasm of unspecified male genital organ
|
Neoplasms | 1.07 | 0.786 – 1.47 | 0.655 | 42 | 455 | exclusion | phecode |
| 187.2 | Malignant neoplasm of testis | Neoplasms | 1.05 | 0.845 – 1.3 | 0.661 | 96 | 873 | exclusion | phecode |
| 187.8 |
Neoplasm of uncertain behavior of male genitalNeoplasm of uncertain behavior of male genital organs
|
Neoplasms | 1.09 | 0.683 – 1.73 | 0.727 | 21 | 195 | exclusion | phecode |
| 189 |
Cancer of urinary organs (incl. kidney andCancer of urinary organs (incl. kidney and bladder)
|
Neoplasms | 1.04 | 0.978 – 1.11 | 0.196 | 1039 | 10911 | exclusion | phecode |
| 189.1 | Cancer of kidney and renal pelvis | Neoplasms | 1.05 | 0.968 – 1.15 | 0.228 | 597 | 6507 | exclusion | phecode |
| 189.11 | Malignant neoplasm of kidney, except pelvis | Neoplasms | 1.07 | 0.974 – 1.17 | 0.163 | 521 | 5731 | exclusion | phecode |
| 189.12 | Malignant neoplasm of renal pelvis | Neoplasms | 0.881 | 0.702 – 1.1 | 0.272 | 76 | 959 | exclusion | phecode |
| 189.2 | Cancer of bladder | Neoplasms | 1.03 | 0.94 – 1.12 | 0.546 | 533 | 6672 | exclusion | phecode |
| 189.21 | Malignant neoplasm of bladder | Neoplasms | 1.01 | 0.917 – 1.11 | 0.893 | 485 | 6160 | exclusion | phecode |
| 189.4 | Malignant neoplasm of other urinary organs | Neoplasms | 1 | 0.867 – 1.16 | 0.962 | 193 | 2701 | exclusion | phecode |
| 190 | Cancer of eye | Neoplasms | 1.07 | 0.816 – 1.39 | 0.64 | 53 | 615 | exclusion | phecode |
| 191 |
Manlignant and unknown neoplasms of brain andManlignant and unknown neoplasms of brain and nervous system
|
Neoplasms | 0.968 | 0.884 – 1.06 | 0.485 | 537 | 5251 | exclusion | phecode |
| 191.1 | Cancer of brain and nervous system | Neoplasms | 0.949 | 0.848 – 1.06 | 0.366 | 358 | 3408 | exclusion | phecode |
| 191.11 | Cancer of brain | Neoplasms | 0.944 | 0.838 – 1.06 | 0.345 | 312 | 2950 | exclusion | phecode |
| 193 | Thyroid cancer | Neoplasms | 0.984 | 0.898 – 1.08 | 0.73 | 533 | 4780 | exclusion | phecode |
| 194 | Cancer of other endocrine glands | Neoplasms | 1.03 | 0.917 – 1.16 | 0.612 | 314 | 2765 | exclusion | phecode |
| 195 | Cancer, suspected or other | Neoplasms | 0.978 | 0.949 – 1.01 | 0.153 | 7752 | 14104 | exclusion | phecode |
| 195.1 | Malignant neoplasm, other | Neoplasms | 0.978 | 0.949 – 1.01 | 0.161 | 7639 | 14089 | exclusion | phecode |
| 195.3 | Malignant neoplasm of head, face, and neck | Neoplasms | 0.862 | 0.775 – 0.958 | 0.00575 | 387 | 4549 | exclusion | phecode |
| 196 | Radiotherapy | Neoplasms | 0.964 | 0.905 – 1.03 | 0.259 | 1136 | 8388 | exclusion | phecode |
| 197 | Chemotherapy | Neoplasms | 0.952 | 0.909 – 0.998 | 0.0403 | 2228 | 12289 | exclusion | phecode |
| 198 | Secondary malignant neoplasm | Neoplasms | 0.988 | 0.944 – 1.03 | 0.593 | 2485 | 12060 | exclusion | phecode |
| 198.1 | Secondary malignancy of lymph nodes | Neoplasms | 0.959 | 0.908 – 1.01 | 0.128 | 1579 | 10866 | exclusion | phecode |
| 198.2 | Secondary malignancy of respiratory organs | Neoplasms | 0.951 | 0.861 – 1.05 | 0.32 | 443 | 4896 | exclusion | phecode |
| 198.3 |
Secondary malignant neoplasm of digestiveSecondary malignant neoplasm of digestive systems
|
Neoplasms | 0.924 | 0.834 – 1.02 | 0.132 | 410 | 4114 | exclusion | phecode |
| 198.4 | Secondary malignant neoplasm of liver | Neoplasms | 0.931 | 0.833 – 1.04 | 0.213 | 354 | 3589 | exclusion | phecode |
| 198.5 | Secondary malignancy of brain/spine | Neoplasms | 1.05 | 0.923 – 1.2 | 0.448 | 259 | 3004 | exclusion | phecode |
| 198.6 | Secondary malignancy of bone | Neoplasms | 0.939 | 0.842 – 1.05 | 0.257 | 366 | 3923 | exclusion | phecode |
| 198.7 | Secondary malignant neoplasm of skin | Neoplasms | 0.85 | 0.717 – 1.01 | 0.0619 | 149 | 1500 | exclusion | phecode |
| 199 | Neoplasm of uncertain behavior | Neoplasms | 0.994 | 0.953 – 1.04 | 0.792 | 2757 | 13633 | exclusion | phecode |
| 199.4 | Neurofibromatosis | Neoplasms | 1.03 | 0.764 – 1.4 | 0.833 | 47 | 477 | exclusion | phecode |
| 200 | Myeloproliferative disease | Neoplasms | 0.988 | 0.901 – 1.08 | 0.802 | 502 | 5393 | exclusion | phecode |
| 200.1 | Polycythemia vera | Neoplasms | 0.935 | 0.752 – 1.16 | 0.546 | 88 | 1121 | exclusion | phecode |
| 201 | Hodgkin's disease | Neoplasms | 1.11 | 0.887 – 1.38 | 0.373 | 91 | 840 | exclusion | phecode |
| 202 | Cancer of other lymphoid, histiocytic tissue | Neoplasms | 0.962 | 0.892 – 1.04 | 0.322 | 736 | 7327 | exclusion | phecode |
| 202.2 | Non-Hodgkins lymphoma | Neoplasms | 0.951 | 0.876 – 1.03 | 0.237 | 633 | 6269 | exclusion | phecode |
| 202.21 | Nodular lymphoma | Neoplasms | 0.9 | 0.803 – 1.01 | 0.0704 | 323 | 3316 | exclusion | phecode |
| 202.22 | Reticulosarcoma | Neoplasms | 1.24 | 0.981 – 1.57 | 0.0718 | 74 | 742 | exclusion | phecode |
| 202.24 | Large cell lymphoma | Neoplasms | 1.16 | 0.915 – 1.47 | 0.222 | 73 | 690 | exclusion | phecode |
| 204 | Leukemia | Neoplasms | 0.993 | 0.887 – 1.11 | 0.909 | 333 | 3108 | exclusion | phecode |
| 204.1 | Lymphoid leukemia | Neoplasms | 1.1 | 0.908 – 1.33 | 0.332 | 117 | 1073 | exclusion | phecode |
| 204.11 | Lymphoid leukemia, acute | Neoplasms | 1.04 | 0.784 – 1.39 | 0.765 | 43 | 366 | exclusion | phecode |
| 204.12 | Lymphoid leukemia, chronic | Neoplasms | 1.12 | 0.878 – 1.42 | 0.369 | 82 | 737 | exclusion | phecode |
| 204.2 | Myeloid leukemia | Neoplasms | 1.05 | 0.877 – 1.25 | 0.611 | 132 | 1232 | exclusion | phecode |
| 204.21 | Myeloid leukemia, acute | Neoplasms | 1.09 | 0.869 – 1.36 | 0.471 | 78 | 720 | exclusion | phecode |
| 204.22 | Myeloid leukemia, chronic | Neoplasms | 1.07 | 0.751 – 1.53 | 0.698 | 33 | 280 | exclusion | phecode |
| 204.4 | Multiple myeloma | Neoplasms | 0.812 | 0.658 – 1 | 0.0533 | 100 | 941 | exclusion | phecode |
| 208 | Benign neoplasm of colon | Neoplasms | 0.999 | 0.966 – 1.03 | 0.947 | 4870 | 17922 | exclusion | phecode |
| 209 | Neuroendocrine tumors | Neoplasms | 0.981 | 0.812 – 1.18 | 0.842 | 130 | 1188 | exclusion | phecode |
| 210 | Benign neoplasm of lip, oral cavity, and pharynx | Neoplasms | 0.984 | 0.917 – 1.06 | 0.661 | 839 | 9407 | exclusion | phecode |
| 211 |
Benign neoplasm of other parts of digestiveBenign neoplasm of other parts of digestive system
|
Neoplasms | 0.975 | 0.94 – 1.01 | 0.174 | 3631 | 18790 | exclusion | phecode |
| 212 |
Benign neoplasm of respiratory andBenign neoplasm of respiratory and intrathoracic organs
|
Neoplasms | 1.01 | 0.936 – 1.09 | 0.791 | 749 | 8814 | exclusion | phecode |
| 213 | Benign neoplasm of bone and articular cartilage | Neoplasms | 0.958 | 0.889 – 1.03 | 0.259 | 786 | 7693 | exclusion | phecode |
| 214 | Lipoma | Neoplasms | 1.05 | 0.975 – 1.14 | 0.193 | 754 | 6929 | exclusion | phecode |
| 214.1 | Lipoma of skin and subcutaneous tissue | Neoplasms | 1.06 | 0.961 – 1.17 | 0.245 | 459 | 4274 | exclusion | phecode |
| 215 |
Other benign neoplasm of connective and otherOther benign neoplasm of connective and other soft tissue
|
Neoplasms | 1.03 | 0.987 – 1.08 | 0.175 | 2334 | 19632 | exclusion | phecode |
| 216 | Benign neoplasm of skin | Neoplasms | 1.02 | 0.985 – 1.05 | 0.318 | 6199 | 17349 | exclusion | phecode |
| 216.1 | Screening for malignant neoplasms of the skin | Neoplasms | 1.06 | 0.871 – 1.3 | 0.546 | 105 | 851 | exclusion | phecode |
| 217 | Vascular hamartomas and non-neoplastic nevi | Neoplasms | 1 | 0.938 – 1.07 | 0.93 | 1009 | 8202 | exclusion | phecode |
| 217.1 | Nevus, non-neoplastic | Neoplasms | 1 | 0.937 – 1.07 | 0.925 | 954 | 7619 | exclusion | phecode |
| 218 | Benign neoplasm of uterus | Neoplasms | 0.988 | 0.944 – 1.03 | 0.598 | 2544 | 9227 | exclusion | phecode |
| 218.1 | Uterine leiomyoma | Neoplasms | 1.02 | 0.961 – 1.09 | 0.459 | 1121 | 8515 | exclusion | phecode |
| 218.2 | Other benign neoplasm of uterus | Neoplasms | 0.966 | 0.919 – 1.02 | 0.172 | 2005 | 9074 | exclusion | phecode |
| 220 | Benign neoplasm of ovary | Neoplasms | 0.986 | 0.899 – 1.08 | 0.766 | 510 | 4593 | exclusion | phecode |
| 221 | Benign neoplasm of other female genital organs | Neoplasms | 1.06 | 0.995 – 1.13 | 0.0731 | 1130 | 7803 | exclusion | phecode |
| 222 | Benign neoplasm of male genital organs | Neoplasms | 0.983 | 0.897 – 1.08 | 0.72 | 535 | 4258 | exclusion | phecode |
| 223 |
Benign neoplasm of kidney and other urinaryBenign neoplasm of kidney and other urinary organs
|
Neoplasms | 1.04 | 0.956 – 1.12 | 0.389 | 698 | 5922 | exclusion | phecode |
| 224 | Benign neoplasm of eye | Neoplasms | 1.01 | 0.902 – 1.12 | 0.926 | 366 | 3341 | exclusion | phecode |
| 224.1 | Benign neoplasm of eye, uveal | Neoplasms | 1.02 | 0.907 – 1.15 | 0.736 | 313 | 2793 | exclusion | phecode |
| 225 |
Benign neoplasm of brain and other parts ofBenign neoplasm of brain and other parts of nervous system
|
Neoplasms | 0.947 | 0.869 – 1.03 | 0.208 | 603 | 5903 | exclusion | phecode |
| 225.1 |
Benign neoplasm of brain, cranial nervesBenign neoplasm of brain, cranial nerves, meninges
|
Neoplasms | 0.928 | 0.844 – 1.02 | 0.123 | 481 | 4636 | exclusion | phecode |
| 225.2 | Benign neoplasm of spinal cord, meninges | Neoplasms | 1.01 | 0.844 – 1.21 | 0.906 | 140 | 1421 | exclusion | phecode |
| 226 | Benign neoplasm of thyroid glands | Neoplasms | 0.968 | 0.895 – 1.05 | 0.424 | 709 | 6711 | exclusion | phecode |
| 227 |
Benign neoplasm of other endocrine glands andBenign neoplasm of other endocrine glands and related structures
|
Neoplasms | 1.02 | 0.955 – 1.1 | 0.496 | 871 | 8360 | exclusion | phecode |
| 227.1 | Benign neoplasm of adrenal gland | Neoplasms | 1.11 | 0.954 – 1.28 | 0.183 | 190 | 2230 | exclusion | phecode |
| 227.2 | Benign neoplasm of parathyroid gland | Neoplasms | 1.01 | 0.916 – 1.12 | 0.779 | 432 | 3959 | exclusion | phecode |
| 227.3 |
Benign neoplasm of pituitary gland andBenign neoplasm of pituitary gland and craniopharyngeal duct (pouch)
|
Neoplasms | 1.02 | 0.895 – 1.16 | 0.756 | 253 | 2106 | exclusion | phecode |
| 228 | Hemangioma and lymphangioma, any site | Neoplasms | 1.01 | 0.948 – 1.07 | 0.824 | 1230 | 10112 | exclusion | phecode |
| 228.1 | Hemangioma of skin and subcutaneous tissue | Neoplasms | 1.04 | 0.964 – 1.12 | 0.314 | 779 | 6301 | exclusion | phecode |
| 229 | Benign neoplasm of unspecified sites | Neoplasms | 0.998 | 0.962 – 1.03 | 0.899 | 3692 | 18380 | exclusion | phecode |
| 229.1 | Benign neoplasm of lymph nodes | Neoplasms | 1.01 | 0.965 – 1.05 | 0.751 | 2644 | 16845 | exclusion | phecode |
| 240 | Simple and unspecified goiter | Endocrine/metabolic | 1 | 0.918 – 1.09 | 0.995 | 587 | 5136 | exclusion | phecode |
| 241 | Nontoxic nodular goiter | Endocrine/metabolic | 1 | 0.949 – 1.06 | 0.953 | 1575 | 11193 | exclusion | phecode |
| 241.1 | Nontoxic uninodular goiter | Endocrine/metabolic | 1.03 | 0.97 – 1.09 | 0.329 | 1228 | 9974 | exclusion | phecode |
| 241.2 | Nontoxic multinodular goiter | Endocrine/metabolic | 0.936 | 0.866 – 1.01 | 0.101 | 716 | 6308 | exclusion | phecode |
| 242 | Thyrotoxicosis with or without goiter | Endocrine/metabolic | 0.986 | 0.91 – 1.07 | 0.722 | 686 | 6800 | exclusion | phecode |
| 242.1 | Graves' disease | Endocrine/metabolic | 1.04 | 0.904 – 1.19 | 0.612 | 240 | 2639 | exclusion | phecode |
| 242.2 | Toxic multinodular goiter | Endocrine/metabolic | 0.887 | 0.684 – 1.15 | 0.368 | 64 | 657 | exclusion | phecode |
| 242.3 | Exophthalmos | Endocrine/metabolic | 0.981 | 0.827 – 1.17 | 0.83 | 146 | 1486 | exclusion | phecode |
| 242.31 | Thyrotoxic exophthalmos | Endocrine/metabolic | 0.983 | 0.755 – 1.28 | 0.9 | 66 | 768 | exclusion | phecode |
| 244 | Hypothyroidism | Endocrine/metabolic | 0.997 | 0.962 – 1.03 | 0.879 | 4208 | 16132 | exclusion | phecode |
| 244.1 | Secondary hypothyroidism | Endocrine/metabolic | 0.977 | 0.912 – 1.05 | 0.507 | 935 | 8705 | exclusion | phecode |
| 244.2 | Acquired hypothyroidism | Endocrine/metabolic | 0.987 | 0.911 – 1.07 | 0.739 | 680 | 6090 | exclusion | phecode |
| 244.4 | Hypothyroidism NOS | Endocrine/metabolic | 0.996 | 0.96 – 1.03 | 0.825 | 3917 | 15881 | exclusion | phecode |
| 245 | Thyroiditis | Endocrine/metabolic | 1.02 | 0.923 – 1.12 | 0.753 | 483 | 4217 | exclusion | phecode |
| 245.2 | Chronic thyroiditis | Endocrine/metabolic | 0.974 | 0.878 – 1.08 | 0.615 | 407 | 3526 | exclusion | phecode |
| 245.21 | Chronic lymphocytic thyroiditis | Endocrine/metabolic | 0.965 | 0.871 – 1.07 | 0.503 | 405 | 3479 | exclusion | phecode |
| 246 | Other disorders of thyroid | Endocrine/metabolic | 0.979 | 0.94 – 1.02 | 0.295 | 3205 | 14789 | exclusion | phecode |
| 246.2 | Thyroid cyst | Endocrine/metabolic | 1.17 | 0.886 – 1.53 | 0.272 | 56 | 476 | exclusion | phecode |
| 246.7 | Abnormal results of function study of thyroid | Endocrine/metabolic | 0.961 | 0.873 – 1.06 | 0.416 | 465 | 4397 | exclusion | phecode |
| 249 | Secondary diabetes mellitus | Endocrine/metabolic | 0.972 | 0.877 – 1.08 | 0.591 | 538 | 3926 | exclusion | phecode |
| 250 | Diabetes mellitus | Endocrine/metabolic | 0.987 | 0.956 – 1.02 | 0.421 | 6437 | 16561 | exclusion | phecode |
| 250.1 | Type 1 diabetes | Endocrine/metabolic | 1.01 | 0.932 – 1.1 | 0.742 | 1285 | 5643 | exclusion | phecode |
| 250.11 | Type 1 diabetes with ketoacidosis | Endocrine/metabolic | 1.12 | 0.871 – 1.44 | 0.376 | 144 | 502 | exclusion | phecode |
| 250.12 | Type 1 diabetes with renal manifestations | Endocrine/metabolic | 1.16 | 0.99 – 1.37 | 0.0663 | 299 | 1267 | exclusion | phecode |
| 250.13 | Type 1 diabetes with ophthalmic manifestations | Endocrine/metabolic | 1.05 | 0.9 – 1.22 | 0.542 | 441 | 1471 | exclusion | phecode |
| 250.14 | Type 1 diabetes with neurological manifestations | Endocrine/metabolic | 1.08 | 0.917 – 1.28 | 0.346 | 330 | 1292 | exclusion | phecode |
| 250.15 |
Diabetes type 1 with peripheral circulatoryDiabetes type 1 with peripheral circulatory disorders
|
Endocrine/metabolic | 1.16 | 0.891 – 1.51 | 0.269 | 76 | 403 | exclusion | phecode |
| 250.2 | Type 2 diabetes | Endocrine/metabolic | 0.975 | 0.938 – 1.01 | 0.189 | 4406 | 15034 | exclusion | phecode |
| 250.21 | Type 2 diabetes with ketoacidosis | Endocrine/metabolic | 1.03 | 0.812 – 1.31 | 0.804 | 131 | 635 | exclusion | phecode |
| 250.22 | Type 2 diabetes with renal manifestations | Endocrine/metabolic | 0.962 | 0.885 – 1.05 | 0.357 | 843 | 6273 | exclusion | phecode |
| 250.23 | Type 2 diabetes with ophthalmic manifestations | Endocrine/metabolic | 1.03 | 0.936 – 1.13 | 0.548 | 818 | 4587 | exclusion | phecode |
| 250.24 | Type 2 diabetes with neurological manifestations | Endocrine/metabolic | 0.984 | 0.911 – 1.06 | 0.687 | 1094 | 7763 | exclusion | phecode |
| 250.25 |
Diabetes type 2 with peripheral circulatoryDiabetes type 2 with peripheral circulatory disorders
|
Endocrine/metabolic | 0.796 | 0.694 – 0.913 | 0.00108 | 315 | 2752 | exclusion | phecode |
| 250.3 | Insulin pump user | Endocrine/metabolic | 0.993 | 0.93 – 1.06 | 0.832 | 1680 | 10052 | exclusion | phecode |
| 250.4 | Abnormal glucose | Endocrine/metabolic | 1.01 | 0.97 – 1.05 | 0.677 | 4136 | 15749 | exclusion | phecode |
| 250.41 | Impaired fasting glucose | Endocrine/metabolic | 0.979 | 0.91 – 1.05 | 0.565 | 927 | 7815 | exclusion | phecode |
| 250.42 | Other abnormal glucose | Endocrine/metabolic | 1.01 | 0.968 – 1.05 | 0.694 | 3717 | 15364 | exclusion | phecode |
| 250.5 | Glycosuria or Acetonuria | Endocrine/metabolic | 0.9 | 0.697 – 1.16 | 0.418 | 69 | 567 | exclusion | phecode |
| 250.6 | Polyneuropathy in diabetes | Endocrine/metabolic | 1.02 | 0.938 – 1.12 | 0.606 | 923 | 6221 | exclusion | phecode |
| 250.7 | Diabetic retinopathy | Endocrine/metabolic | 1.07 | 0.993 – 1.16 | 0.0746 | 863 | 4912 | exclusion | phecode |
| 251 | Other disorders of pancreatic internal secretion | Endocrine/metabolic | 0.995 | 0.905 – 1.09 | 0.911 | 488 | 4265 | exclusion | phecode |
| 251.1 | Hypoglycemia | Endocrine/metabolic | 1.04 | 0.937 – 1.15 | 0.495 | 611 | 4269 | exclusion | phecode |
| 252 | Disorders of parathyroid gland | Endocrine/metabolic | 1.04 | 0.978 – 1.1 | 0.215 | 1209 | 11004 | exclusion | phecode |
| 252.1 | Hyperparathyroidism | Endocrine/metabolic | 1.03 | 0.969 – 1.1 | 0.331 | 1118 | 10108 | exclusion | phecode |
| 252.2 | Hypoparathyroidism | Endocrine/metabolic | 1.03 | 0.901 – 1.17 | 0.7 | 263 | 2585 | exclusion | phecode |
| 253 |
Disorders of the pituitary gland and itsDisorders of the pituitary gland and its hypothalamic control
|
Endocrine/metabolic | 1.04 | 0.941 – 1.14 | 0.47 | 464 | 4262 | exclusion | phecode |
| 253.1 | Pituitary hyperfunction | Endocrine/metabolic | 1.06 | 0.899 – 1.25 | 0.482 | 145 | 1379 | exclusion | phecode |
| 253.11 | Acromegaly and gigantism | Endocrine/metabolic | 0.986 | 0.724 – 1.34 | 0.928 | 44 | 438 | exclusion | phecode |
| 253.2 | Pituitary hypofunction | Endocrine/metabolic | 1.04 | 0.867 – 1.26 | 0.648 | 120 | 1087 | exclusion | phecode |
| 253.3 | Diabetes insipidus | Endocrine/metabolic | 1.28 | 0.941 – 1.75 | 0.115 | 40 | 451 | exclusion | phecode |
| 253.4 | Anterior pituitary disorders | Endocrine/metabolic | 1.01 | 0.797 – 1.28 | 0.948 | 73 | 597 | exclusion | phecode |
| 253.7 | Other disorders of neurohypophysis | Endocrine/metabolic | 0.947 | 0.704 – 1.27 | 0.717 | 46 | 493 | exclusion | phecode |
| 255 | Disorders of adrenal glands | Endocrine/metabolic | 1.02 | 0.948 – 1.11 | 0.549 | 721 | 7341 | exclusion | phecode |
| 255.1 | Adrenal hyperfunction | Endocrine/metabolic | 1 | 0.87 – 1.15 | 0.996 | 222 | 1923 | exclusion | phecode |
| 255.11 | Cushing's syndrome | Endocrine/metabolic | 0.921 | 0.756 – 1.12 | 0.415 | 111 | 968 | exclusion | phecode |
| 255.12 | Hyperaldosteronism | Endocrine/metabolic | 1.02 | 0.811 – 1.28 | 0.879 | 78 | 661 | exclusion | phecode |
| 255.2 | Adrenal hypofunction | Endocrine/metabolic | 1.09 | 0.97 – 1.23 | 0.147 | 324 | 3094 | exclusion | phecode |
| 255.21 | Glucocorticoid deficiency | Endocrine/metabolic | 1.13 | 0.999 – 1.27 | 0.0529 | 304 | 2958 | exclusion | phecode |
| 256 | Ovarian dysfunction | Endocrine/metabolic | 0.94 | 0.869 – 1.02 | 0.119 | 744 | 5911 | exclusion | phecode |
| 256.4 | Polycystic ovaries | Endocrine/metabolic | 0.915 | 0.832 – 1.01 | 0.0701 | 490 | 4092 | exclusion | phecode |
| 257 | Testicular dysfunction | Endocrine/metabolic | 1.03 | 0.94 – 1.14 | 0.492 | 494 | 3977 | exclusion | phecode |
| 257.1 | Testicular hypofunction | Endocrine/metabolic | 1.03 | 0.936 – 1.14 | 0.525 | 474 | 3820 | exclusion | phecode |
| 258 | Iatrogenic endocrine disorders | Endocrine/metabolic | 1.24 | 0.908 – 1.7 | 0.174 | 40 | 471 | exclusion | phecode |
| 258.1 | Postablative ovarian failure | Endocrine/metabolic | 0.927 | 0.718 – 1.2 | 0.564 | 72 | 606 | exclusion | phecode |
| 259 | Other endocrine disorders | Endocrine/metabolic | 1.03 | 0.942 – 1.13 | 0.511 | 539 | 5198 | exclusion | phecode |
| 260 | Protein-calorie malnutrition | Endocrine/metabolic | 0.972 | 0.913 – 1.04 | 0.379 | 1087 | 12951 | exclusion | phecode |
| 260.1 | Cachexia | Endocrine/metabolic | 1.09 | 0.885 – 1.35 | 0.41 | 96 | 1375 | exclusion | phecode |
| 260.2 | severe protein-calorie malnutrition | Endocrine/metabolic | 0.998 | 0.916 – 1.09 | 0.956 | 599 | 7962 | exclusion | phecode |
| 260.22 | Nutritional marasmus | Endocrine/metabolic | 0.967 | 0.84 – 1.11 | 0.642 | 216 | 2965 | exclusion | phecode |
| 260.3 | Adult failure to thrive | Endocrine/metabolic | 1.01 | 0.88 – 1.15 | 0.923 | 226 | 2884 | exclusion | phecode |
| 260.6 | Anorexia | Endocrine/metabolic | 0.976 | 0.874 – 1.09 | 0.671 | 353 | 4145 | exclusion | phecode |
| 260.7 | Polyphagia | Endocrine/metabolic | 0.96 | 0.69 – 1.34 | 0.808 | 35 | 363 | exclusion | phecode |
| 261 | Vitamin deficiency | Endocrine/metabolic | 0.979 | 0.945 – 1.01 | 0.239 | 4031 | 17987 | exclusion | phecode |
| 261.1 | Vitamin A deficiency | Endocrine/metabolic | 0.783 | 0.558 – 1.1 | 0.158 | 35 | 385 | exclusion | phecode |
| 261.2 | Vitamin B-complex deficiencies | Endocrine/metabolic | 0.995 | 0.896 – 1.11 | 0.928 | 375 | 4141 | exclusion | phecode |
| 261.4 | Vitamin D deficiency | Endocrine/metabolic | 0.983 | 0.948 – 1.02 | 0.357 | 3842 | 18024 | exclusion | phecode |
| 261.41 | Rickets or osteomalacia | Endocrine/metabolic | 0.931 | 0.651 – 1.33 | 0.697 | 28 | 276 | exclusion | phecode |
| 262 | Mineral deficiency NEC | Endocrine/metabolic | 0.937 | 0.863 – 1.02 | 0.124 | 629 | 6041 | exclusion | phecode |
| 263 | Other nutritional deficiency | Endocrine/metabolic | 0.971 | 0.903 – 1.04 | 0.431 | 830 | 8072 | exclusion | phecode |
| 264 | Lack of normal physiological development | Endocrine/metabolic | 1.03 | 0.862 – 1.22 | 0.765 | 141 | 1346 | exclusion | phecode |
| 264.2 | Failure to thrive (childhood) | Endocrine/metabolic | 0.962 | 0.739 – 1.25 | 0.773 | 61 | 659 | exclusion | phecode |
| 264.9 |
Lack of normal physiological developmentLack of normal physiological development, unspecified
|
Endocrine/metabolic | 1.04 | 0.785 – 1.39 | 0.769 | 59 | 484 | exclusion | phecode |
| 269 | Proteinuria | Endocrine/metabolic | 1.03 | 0.957 – 1.11 | 0.43 | 838 | 6883 | exclusion | phecode |
| 270 |
Disorders of protein plasma/amino-acidDisorders of protein plasma/amino-acid transport and metabolism
|
Endocrine/metabolic | 0.971 | 0.88 – 1.07 | 0.562 | 459 | 4637 | exclusion | phecode |
| 270.1 | Disturbances of amino-acid transport | Endocrine/metabolic | 1.05 | 0.851 – 1.3 | 0.638 | 107 | 898 | exclusion | phecode |
| 270.11 |
Disturbances of sulphur-bearing amino-acidDisturbances of sulphur-bearing amino-acid metabolism
|
Endocrine/metabolic | 1.05 | 0.832 – 1.33 | 0.668 | 88 | 705 | exclusion | phecode |
| 270.2 | Disorders of amino-acid metabolism | Endocrine/metabolic | 0.907 | 0.685 – 1.2 | 0.493 | 51 | 487 | exclusion | phecode |
| 270.3 | Disorders of plasma protein metabolism | Endocrine/metabolic | 0.958 | 0.852 – 1.08 | 0.469 | 321 | 3462 | exclusion | phecode |
| 270.32 | Paraproteinemia | Endocrine/metabolic | 0.958 | 0.811 – 1.13 | 0.612 | 163 | 1708 | exclusion | phecode |
| 270.33 | Amyloidosis | Endocrine/metabolic | 0.697 | 0.473 – 1.03 | 0.0676 | 30 | 316 | exclusion | phecode |
| 270.34 | Alpha-1-antitrypsin deficiency | Endocrine/metabolic | 1.04 | 0.747 – 1.45 | 0.818 | 33 | 346 | exclusion | phecode |
| 270.38 |
Other specified disorders of plasma proteinOther specified disorders of plasma protein metabolism
|
Endocrine/metabolic | 1.01 | 0.852 – 1.21 | 0.869 | 134 | 1481 | exclusion | phecode |
| 271 |
Disorders of carbohydrate transport andDisorders of carbohydrate transport and metabolism
|
Endocrine/metabolic | 1.02 | 0.966 – 1.08 | 0.46 | 1474 | 13779 | exclusion | phecode |
| 271.3 |
Intestinal disaccharidase deficiencies andIntestinal disaccharidase deficiencies and disaccharide malabsorption
|
Endocrine/metabolic | 1.02 | 0.966 – 1.08 | 0.455 | 1430 | 13379 | exclusion | phecode |
| 271.9 |
Other disorders of carbohydrate transport andOther disorders of carbohydrate transport and metabolism
|
Endocrine/metabolic | 0.887 | 0.667 – 1.18 | 0.411 | 55 | 554 | exclusion | phecode |
| 272 | Disorders of lipoid metabolism | Endocrine/metabolic | 1.01 | 0.978 – 1.04 | 0.613 | 8564 | 14209 | exclusion | phecode |
| 272.1 | Hyperlipidemia | Endocrine/metabolic | 1.01 | 0.978 – 1.04 | 0.597 | 8540 | 14195 | exclusion | phecode |
| 272.11 | Hypercholesterolemia | Endocrine/metabolic | 1.01 | 0.967 – 1.06 | 0.606 | 2670 | 11161 | exclusion | phecode |
| 272.12 | Hyperglyceridemia | Endocrine/metabolic | 1 | 0.923 – 1.09 | 0.982 | 675 | 5882 | exclusion | phecode |
| 272.13 | Mixed hyperlipidemia | Endocrine/metabolic | 1 | 0.946 – 1.06 | 0.992 | 1681 | 9400 | exclusion | phecode |
| 272.9 | Unspecified disorder of lipoid metabolism | Endocrine/metabolic | 0.906 | 0.775 – 1.06 | 0.213 | 167 | 1496 | exclusion | phecode |
| 274 | Gout and other crystal arthropathies | Endocrine/metabolic | 1.01 | 0.947 – 1.08 | 0.782 | 1082 | 10404 | exclusion | phecode |
| 274.1 | Gout | Endocrine/metabolic | 1 | 0.94 – 1.07 | 0.917 | 1026 | 9989 | exclusion | phecode |
| 274.11 | Gouty arthropathy | Endocrine/metabolic | 1.04 | 0.947 – 1.15 | 0.402 | 485 | 4860 | exclusion | phecode |
| 274.2 | Crystal arthropathies | Endocrine/metabolic | 1.09 | 0.88 – 1.34 | 0.444 | 89 | 867 | exclusion | phecode |
| 274.21 | Chondrocalcinosis | Endocrine/metabolic | 1.05 | 0.848 – 1.3 | 0.644 | 84 | 796 | exclusion | phecode |
| 275 | Disorders of mineral metabolism | Endocrine/metabolic | 0.992 | 0.947 – 1.04 | 0.734 | 2069 | 18268 | exclusion | phecode |
| 275.1 | Disorders of iron metabolism | Hematopoietic | 0.876 | 0.717 – 1.07 | 0.196 | 107 | 1060 | exclusion | phecode |
| 275.11 | Hereditary hemochromatosis | Hematopoietic | 0.809 | 0.591 – 1.11 | 0.185 | 44 | 469 | exclusion | phecode |
| 275.2 | Disorders of copper metabolism | Endocrine/metabolic | 1.08 | 0.776 – 1.5 | 0.648 | 41 | 330 | exclusion | phecode |
| 275.3 | Disorders of magnesium metabolism | Endocrine/metabolic | 0.991 | 0.903 – 1.09 | 0.849 | 496 | 5448 | exclusion | phecode |
| 275.5 | Disorders of calcium/phosphorus metabolism | Endocrine/metabolic | 0.986 | 0.936 – 1.04 | 0.595 | 1627 | 15580 | exclusion | phecode |
| 275.51 | Hypocalcemia | Endocrine/metabolic | 1.02 | 0.92 – 1.12 | 0.74 | 431 | 4458 | exclusion | phecode |
| 275.53 | Disorders of phosphorus metabolism | Endocrine/metabolic | 1.03 | 0.949 – 1.12 | 0.484 | 619 | 6578 | exclusion | phecode |
| 275.6 | Hypercalcemia | Endocrine/metabolic | 0.969 | 0.898 – 1.05 | 0.419 | 744 | 7233 | exclusion | phecode |
| 276 |
Disorders of fluid, electrolyte, and acid-baseDisorders of fluid, electrolyte, and acid-base balance
|
Endocrine/metabolic | 0.964 | 0.93 – 0.998 | 0.0374 | 4035 | 19358 | exclusion | phecode |
| 276.1 | Electrolyte imbalance | Endocrine/metabolic | 0.973 | 0.934 – 1.01 | 0.205 | 2699 | 17482 | exclusion | phecode |
| 276.11 | Hyperosmolality and/or hypernatremia | Endocrine/metabolic | 0.955 | 0.828 – 1.1 | 0.521 | 209 | 2607 | exclusion | phecode |
| 276.12 | Hyposmolality and/or hyponatremia | Endocrine/metabolic | 0.985 | 0.924 – 1.05 | 0.649 | 1027 | 11282 | exclusion | phecode |
| 276.13 | Hyperpotassemia | Endocrine/metabolic | 0.992 | 0.935 – 1.05 | 0.796 | 1240 | 12307 | exclusion | phecode |
| 276.14 | Hypopotassemia | Endocrine/metabolic | 0.964 | 0.902 – 1.03 | 0.286 | 981 | 10600 | exclusion | phecode |
| 276.4 | Acid-base balance disorder | Endocrine/metabolic | 0.999 | 0.931 – 1.07 | 0.98 | 858 | 9898 | exclusion | phecode |
| 276.41 | Acidosis | Endocrine/metabolic | 0.981 | 0.908 – 1.06 | 0.62 | 734 | 8562 | exclusion | phecode |
| 276.42 | Alkalosis | Endocrine/metabolic | 0.974 | 0.841 – 1.13 | 0.722 | 183 | 2293 | exclusion | phecode |
| 276.5 | Hypovolemia | Endocrine/metabolic | 0.979 | 0.935 – 1.03 | 0.371 | 2073 | 17717 | exclusion | phecode |
| 276.6 | Fluid overload | Endocrine/metabolic | 1.01 | 0.921 – 1.1 | 0.868 | 528 | 6287 | exclusion | phecode |
| 276.8 | Polydipsia | Endocrine/metabolic | 0.786 | 0.622 – 0.992 | 0.0424 | 75 | 687 | exclusion | phecode |
| 277 | Other disorders of metabolism | Endocrine/metabolic | 0.981 | 0.937 – 1.03 | 0.419 | 2106 | 17510 | exclusion | phecode |
| 277.2 |
Other disorders of purine and pyrimidineOther disorders of purine and pyrimidine metabolism
|
Endocrine/metabolic | 1.16 | 0.998 – 1.34 | 0.0534 | 191 | 1939 | exclusion | phecode |
| 277.4 | Disorders of bilirubin excretion | Endocrine/metabolic | 1.12 | 1.01 – 1.24 | 0.0338 | 398 | 3406 | exclusion | phecode |
| 277.5 | Other disorders of lipoid metabolism | Endocrine/metabolic | 1.01 | 0.917 – 1.11 | 0.874 | 498 | 4604 | exclusion | phecode |
| 277.51 | Lipoprotein disorders | Endocrine/metabolic | 1 | 0.902 – 1.11 | 0.988 | 411 | 3796 | exclusion | phecode |
| 277.7 | Dysmetabolic syndrome X | Endocrine/metabolic | 0.995 | 0.906 – 1.09 | 0.917 | 504 | 4257 | exclusion | phecode |
| 278 | Overweight, obesity and other hyperalimentation | Endocrine/metabolic | 1.02 | 0.996 – 1.05 | 0.0886 | 9544 | 14178 | exclusion | phecode |
| 278.1 | Obesity | Endocrine/metabolic | 1.02 | 0.993 – 1.05 | 0.148 | 8304 | 14169 | exclusion | phecode |
| 278.11 | Morbid obesity | Endocrine/metabolic | 1.02 | 0.98 – 1.05 | 0.392 | 4148 | 14064 | exclusion | phecode |
| 278.3 | Localized adiposity | Endocrine/metabolic | 1.15 | 0.988 – 1.34 | 0.0708 | 189 | 1695 | exclusion | phecode |
| 278.4 | Abnormal weight gain | Endocrine/metabolic | 1 | 0.944 – 1.07 | 0.878 | 1156 | 9429 | exclusion | phecode |
| 279 | Disorders involving the immune mechanism | Endocrine/metabolic | 0.967 | 0.916 – 1.02 | 0.226 | 1507 | 14500 | exclusion | phecode |
| 279.1 | Immunity deficiency | Endocrine/metabolic | 1.01 | 0.927 – 1.1 | 0.822 | 593 | 5845 | exclusion | phecode |
| 279.11 | Deficiency of humoral immunity | Endocrine/metabolic | 0.96 | 0.819 – 1.13 | 0.615 | 169 | 1665 | exclusion | phecode |
| 279.2 | Autoimmune disease NEC | Endocrine/metabolic | 0.914 | 0.825 – 1.01 | 0.0833 | 425 | 4007 | exclusion | phecode |
| 279.7 | Other immunological findings | Endocrine/metabolic | 0.996 | 0.954 – 1.04 | 0.837 | 2480 | 18177 | exclusion | phecode |
| 279.8 |
Other specified disorders involving the immuneOther specified disorders involving the immune mechanism
|
Endocrine/metabolic | 0.917 | 0.817 – 1.03 | 0.139 | 340 | 3188 | exclusion | phecode |
| 280 | Iron deficiency anemias | Hematopoietic | 0.987 | 0.943 – 1.03 | 0.555 | 2288 | 15721 | exclusion | phecode |
| 280.1 |
Iron deficiency anemias, unspecified or not dueIron deficiency anemias, unspecified or not due to blood loss
|
Hematopoietic | 0.984 | 0.94 – 1.03 | 0.487 | 2219 | 15629 | exclusion | phecode |
| 280.2 |
Iron deficiency anemia secondary to blood lossIron deficiency anemia secondary to blood loss (chronic)
|
Hematopoietic | 0.954 | 0.889 – 1.02 | 0.197 | 855 | 8522 | exclusion | phecode |
| 281 | Other deficiency anemia | Hematopoietic | 0.965 | 0.848 – 1.1 | 0.594 | 245 | 2528 | exclusion | phecode |
| 281.1 | Megaloblastic anemia | Hematopoietic | 0.988 | 0.832 – 1.17 | 0.886 | 136 | 1267 | exclusion | phecode |
| 281.11 | Pernicious anemia | Hematopoietic | 1 | 0.782 – 1.29 | 0.974 | 65 | 553 | exclusion | phecode |
| 281.12 | Other vitamin B12 deficiency anemia | Hematopoietic | 1.01 | 0.835 – 1.23 | 0.886 | 106 | 915 | exclusion | phecode |
| 281.9 | Deficiency anemias | Hematopoietic | 0.897 | 0.749 – 1.07 | 0.239 | 125 | 1355 | exclusion | phecode |
| 282 | Hereditary hemolytic anemias | Hematopoietic | 0.841 | 0.707 – 1 | 0.0505 | 150 | 1577 | exclusion | phecode |
| 282.8 | Other hemoglobinopathies | Hematopoietic | 0.766 | 0.62 – 0.946 | 0.0132 | 105 | 1048 | exclusion | phecode |
| 282.9 | Other hereditary hemolytic anemias | Hematopoietic | 0.829 | 0.656 – 1.05 | 0.115 | 81 | 926 | exclusion | phecode |
| 283 | Acquired hemolytic anemias | Hematopoietic | 0.983 | 0.769 – 1.26 | 0.89 | 68 | 733 | exclusion | phecode |
| 283.1 | Autoimmune hemolytic anemias | Hematopoietic | 1.2 | 0.784 – 1.85 | 0.397 | 25 | 313 | exclusion | phecode |
| 284 | Aplastic anemia | Hematopoietic | 1.17 | 1.05 – 1.32 | 0.00585 | 317 | 3404 | exclusion | phecode |
| 284.1 | Pancytopenia | Hematopoietic | 1.17 | 1.03 – 1.32 | 0.0138 | 269 | 2970 | exclusion | phecode |
| 285 | Other anemias | Hematopoietic | 0.983 | 0.953 – 1.01 | 0.283 | 5589 | 17381 | exclusion | phecode |
| 285.1 | Acute posthemorrhagic anemia | Hematopoietic | 0.982 | 0.93 – 1.04 | 0.522 | 1443 | 13681 | exclusion | phecode |
| 285.2 | Anemia of chronic disease | Hematopoietic | 1.01 | 0.942 – 1.08 | 0.811 | 950 | 9642 | exclusion | phecode |
| 285.21 | Anemia in chronic kidney disease | Hematopoietic | 1.06 | 0.958 – 1.17 | 0.263 | 430 | 4367 | exclusion | phecode |
| 285.22 | Anemia in neoplastic disease | Hematopoietic | 1.05 | 0.936 – 1.18 | 0.41 | 336 | 3382 | exclusion | phecode |
| 286 | Coagulation defects | Hematopoietic | 0.981 | 0.934 – 1.03 | 0.451 | 1783 | 16625 | exclusion | phecode |
| 286.1 | Congenital coagulation defects | Hematopoietic | 1.1 | 0.922 – 1.31 | 0.296 | 141 | 1339 | exclusion | phecode |
| 286.11 | Von willebrand's disease | Hematopoietic | 1.11 | 0.821 – 1.49 | 0.508 | 46 | 414 | exclusion | phecode |
| 286.12 |
Congenital deficiency of other clotting factorsCongenital deficiency of other clotting factors (including factor VII)
|
Hematopoietic | 1.08 | 0.848 – 1.37 | 0.535 | 74 | 691 | exclusion | phecode |
| 286.2 |
Encounter for long-term (current) use ofEncounter for long-term (current) use of anticoagulants
|
Hematopoietic | 0.963 | 0.91 – 1.02 | 0.185 | 1408 | 12481 | exclusion | phecode |
| 286.3 |
Coagulation defects complicating pregnancy orCoagulation defects complicating pregnancy or postpartum
|
Hematopoietic | 1.15 | 0.888 – 1.48 | 0.294 | 63 | 590 | exclusion | phecode |
| 286.4 | Acquired coagulation factor deficiency | Hematopoietic | 0.934 | 0.76 – 1.15 | 0.52 | 101 | 1238 | exclusion | phecode |
| 286.5 |
Hemorrhagic disorder due to intrinsicHemorrhagic disorder due to intrinsic circulating anticoagulants
|
Hematopoietic | 1.03 | 0.758 – 1.39 | 0.867 | 45 | 609 | exclusion | phecode |
| 286.6 | Defibrination syndrome | Hematopoietic | 0.981 | 0.924 – 1.04 | 0.534 | 1208 | 12434 | exclusion | phecode |
| 286.7 | Other and unspecified coagulation defects | Hematopoietic | 0.983 | 0.93 – 1.04 | 0.535 | 1434 | 14398 | exclusion | phecode |
| 286.8 | Hypercoagulable state | Hematopoietic | 0.968 | 0.877 – 1.07 | 0.513 | 441 | 4275 | exclusion | phecode |
| 286.81 | Primary hypercoagulable state | Hematopoietic | 0.973 | 0.879 – 1.08 | 0.593 | 424 | 4119 | exclusion | phecode |
| 286.9 | Abnormal coagulation profile | Hematopoietic | 0.956 | 0.872 – 1.05 | 0.34 | 500 | 5420 | exclusion | phecode |
| 287 | Purpura and other hemorrhagic conditions | Hematopoietic | 1.01 | 0.961 – 1.07 | 0.596 | 1484 | 14018 | exclusion | phecode |
| 287.1 | Spontaneous ecchymoses | Hematopoietic | 0.967 | 0.785 – 1.19 | 0.75 | 105 | 1097 | exclusion | phecode |
| 287.3 | Thrombocytopenia | Hematopoietic | 1.01 | 0.956 – 1.07 | 0.664 | 1307 | 12834 | exclusion | phecode |
| 287.31 | Primary thrombocytopenia | Hematopoietic | 1.05 | 0.932 – 1.19 | 0.398 | 274 | 2880 | exclusion | phecode |
| 287.32 | Secondary thrombocytopenia | Hematopoietic | 1.02 | 0.894 – 1.16 | 0.789 | 261 | 2715 | exclusion | phecode |
| 287.4 | Qualitative platelet defects | Hematopoietic | 0.98 | 0.742 – 1.29 | 0.884 | 57 | 559 | exclusion | phecode |
| 288 | Diseases of white blood cells | Hematopoietic | 0.947 | 0.905 – 0.991 | 0.0178 | 2182 | 18654 | exclusion | phecode |
| 288.1 | Decreased white blood cell count | Hematopoietic | 0.939 | 0.872 – 1.01 | 0.0919 | 828 | 7999 | exclusion | phecode |
| 288.11 | Neutropenia | Hematopoietic | 1.01 | 0.927 – 1.11 | 0.769 | 549 | 5535 | exclusion | phecode |
| 288.2 | Elevated white blood cell count | Hematopoietic | 0.937 | 0.892 – 0.985 | 0.0105 | 1777 | 17698 | exclusion | phecode |
| 288.3 | Eosinophilia | Hematopoietic | 0.89 | 0.723 – 1.09 | 0.27 | 109 | 969 | exclusion | phecode |
| 289 | Other diseases of blood and blood-forming organs | Hematopoietic | 0.968 | 0.902 – 1.04 | 0.361 | 879 | 8826 | exclusion | phecode |
| 289.3 |
Personal history of diseases of blood andPersonal history of diseases of blood and blood-forming organs
|
Hematopoietic | 0.974 | 0.886 – 1.07 | 0.576 | 499 | 4716 | exclusion | phecode |
| 289.4 | Lymphadenitis | Hematopoietic | 1.04 | 0.992 – 1.09 | 0.102 | 1854 | 17651 | exclusion | phecode |
| 289.5 | Diseases of spleen | Hematopoietic | 1.08 | 0.926 – 1.27 | 0.315 | 171 | 1969 | exclusion | phecode |
| 289.8 | Polycythemia, secondary | Hematopoietic | 1.01 | 0.828 – 1.22 | 0.955 | 112 | 1235 | exclusion | phecode |
| 289.9 | Abnormality of red blood cells | Hematopoietic | 1.02 | 0.873 – 1.19 | 0.802 | 170 | 1888 | exclusion | phecode |
| 290 |
Delirium dementia and amnestic and otherDelirium dementia and amnestic and other cognitive disorders
|
Mental Disorders | 0.932 | 0.85 – 1.02 | 0.133 | 496 | 5248 | exclusion | phecode |
| 290.1 | Dementias | Mental Disorders | 0.889 | 0.775 – 1.02 | 0.0964 | 217 | 2168 | exclusion | phecode |
| 290.11 | Alzheimer's disease | Mental Disorders | 0.717 | 0.542 – 0.947 | 0.0192 | 56 | 639 | exclusion | phecode |
| 290.12 | Dementia with cerebral degenerations | Mental Disorders | 0.931 | 0.667 – 1.3 | 0.676 | 36 | 376 | exclusion | phecode |
| 290.13 | Senile dementia | Mental Disorders | 0.9 | 0.755 – 1.07 | 0.242 | 130 | 1357 | exclusion | phecode |
| 290.16 | Vascular dementia | Mental Disorders | 0.943 | 0.66 – 1.35 | 0.745 | 32 | 338 | exclusion | phecode |
| 290.2 | Delirium due to conditions classified elsewhere | Mental Disorders | 0.904 | 0.796 – 1.03 | 0.122 | 262 | 3400 | exclusion | phecode |
| 290.3 |
Other persistent mental disorders due toOther persistent mental disorders due to conditions classified elsewhere
|
Mental Disorders | 0.956 | 0.864 – 1.06 | 0.375 | 411 | 4191 | exclusion | phecode |
| 291 |
Other specified nonpsychotic and/or transientOther specified nonpsychotic and/or transient mental disorders
|
Mental Disorders | 1.02 | 0.959 – 1.08 | 0.563 | 1190 | 12645 | exclusion | phecode |
| 291.1 |
Transient mental disorders due to conditionsTransient mental disorders due to conditions classified elsewhere
|
Mental Disorders | 1.28 | 1.04 – 1.57 | 0.0187 | 98 | 940 | exclusion | phecode |
| 291.4 |
Specific nonpsychotic mental disorders due toSpecific nonpsychotic mental disorders due to brain damage
|
Mental Disorders | 1.01 | 0.879 – 1.15 | 0.924 | 233 | 2413 | exclusion | phecode |
| 291.8 | Alteration of consciousness | Mental Disorders | 1 | 0.937 – 1.07 | 0.934 | 919 | 10003 | exclusion | phecode |
| 292 | Neurological disorders | Mental Disorders | 0.984 | 0.943 – 1.03 | 0.453 | 2528 | 19678 | exclusion | phecode |
| 292.1 | Aphasia/speech disturbance | Mental Disorders | 1.06 | 0.989 – 1.13 | 0.101 | 911 | 9605 | exclusion | phecode |
| 292.11 | Aphasia | Mental Disorders | 1.02 | 0.911 – 1.15 | 0.709 | 316 | 3147 | exclusion | phecode |
| 292.12 | Symbolic dysfunction | Mental Disorders | 0.981 | 0.794 – 1.21 | 0.86 | 94 | 968 | exclusion | phecode |
| 292.2 | Mild cognitive impairment | Mental Disorders | 1.06 | 0.911 – 1.23 | 0.45 | 170 | 1757 | exclusion | phecode |
| 292.3 | Memory loss | Mental Disorders | 0.94 | 0.877 – 1.01 | 0.0826 | 892 | 8898 | exclusion | phecode |
| 292.4 | Altered mental status | Mental Disorders | 0.966 | 0.904 – 1.03 | 0.311 | 963 | 10882 | exclusion | phecode |
| 292.5 | Transient alteration of awareness | Mental Disorders | 1.04 | 0.893 – 1.2 | 0.636 | 189 | 2201 | exclusion | phecode |
| 292.6 | Hallucinations | Mental Disorders | 0.938 | 0.754 – 1.17 | 0.564 | 86 | 1054 | exclusion | phecode |
| 293 | Symptoms involving head and neck | Mental Disorders | 0.931 | 0.81 – 1.07 | 0.308 | 217 | 2085 | exclusion | phecode |
| 293.1 |
Swelling, mass, or lump in head and neckSwelling, mass, or lump in head and neck [Space-occupying lesion, intracranial NOS]
|
Mental Disorders | 1.04 | 0.99 – 1.08 | 0.129 | 2094 | 19250 | exclusion | phecode |
| 295 | Schizophrenia and other psychotic disorders | Mental Disorders | 0.989 | 0.886 – 1.1 | 0.837 | 356 | 4174 | exclusion | phecode |
| 295.1 | Schizophrenia | Mental Disorders | 1.02 | 0.743 – 1.39 | 0.916 | 42 | 732 | exclusion | phecode |
| 295.2 | Paranoid disorders | Mental Disorders | 0.864 | 0.631 – 1.18 | 0.363 | 47 | 567 | exclusion | phecode |
| 295.3 | Psychosis | Mental Disorders | 0.982 | 0.872 – 1.11 | 0.765 | 305 | 3368 | exclusion | phecode |
| 296 | Mood disorders | Mental Disorders | 1.02 | 0.992 – 1.06 | 0.146 | 6873 | 11367 | exclusion | phecode |
| 296.1 | Bipolar | Mental Disorders | 0.97 | 0.882 – 1.07 | 0.535 | 474 | 6515 | exclusion | phecode |
| 296.2 | Depression | Mental Disorders | 1.03 | 0.993 – 1.06 | 0.124 | 6627 | 11365 | exclusion | phecode |
| 296.22 | Major depressive disorder | Mental Disorders | 1.03 | 0.996 – 1.06 | 0.0817 | 6155 | 11363 | exclusion | phecode |
| 297 | Suicidal ideation or attempt | Mental Disorders | 1.06 | 0.955 – 1.18 | 0.266 | 391 | 5253 | exclusion | phecode |
| 297.1 | Suicidal ideation | Mental Disorders | 1.11 | 0.981 – 1.25 | 0.101 | 309 | 4261 | exclusion | phecode |
| 297.2 | Suicide or self-inflicted injury | Mental Disorders | 1.02 | 0.831 – 1.24 | 0.872 | 101 | 1575 | exclusion | phecode |
| 300 | Anxiety disorders | Mental Disorders | 1.03 | 0.998 – 1.06 | 0.0624 | 7091 | 11360 | exclusion | phecode |
| 300.1 | Anxiety disorder | Mental Disorders | 1.03 | 0.996 – 1.06 | 0.0851 | 6652 | 11364 | exclusion | phecode |
| 300.11 | Generalized anxiety disorder | Mental Disorders | 1 | 0.957 – 1.05 | 0.959 | 2582 | 11100 | exclusion | phecode |
| 300.12 | Agorophobia, social phobia, and panic disorder | Mental Disorders | 1.06 | 0.969 – 1.15 | 0.216 | 645 | 6598 | exclusion | phecode |
| 300.13 | Phobia | Mental Disorders | 1.05 | 0.956 – 1.16 | 0.304 | 507 | 5284 | exclusion | phecode |
| 300.3 | Obsessive-compulsive disorders | Mental Disorders | 0.963 | 0.828 – 1.12 | 0.629 | 201 | 1778 | exclusion | phecode |
| 300.4 | Dysthymic disorder | Mental Disorders | 1.03 | 0.962 – 1.09 | 0.435 | 1121 | 9202 | exclusion | phecode |
| 300.8 | Acute reaction to stress | Mental Disorders | 1.14 | 0.998 – 1.29 | 0.0542 | 258 | 2780 | exclusion | phecode |
| 300.9 | Posttraumatic stress disorder | Mental Disorders | 0.992 | 0.882 – 1.12 | 0.899 | 320 | 4569 | exclusion | phecode |
| 301 | Personality disorders | Mental Disorders | 1.03 | 0.885 – 1.19 | 0.725 | 198 | 2644 | exclusion | phecode |
| 301.2 | Antisocial/borderline personality disorder | Mental Disorders | 0.868 | 0.694 – 1.09 | 0.213 | 84 | 1389 | exclusion | phecode |
| 302 | Sexual and gender identity disorders | Mental Disorders | 1.01 | 0.952 – 1.06 | 0.814 | 1727 | 6930 | exclusion | phecode |
| 302.1 | Decreased libido | Mental Disorders | 0.97 | 0.847 – 1.11 | 0.665 | 235 | 2354 | exclusion | phecode |
| 303 | Psychogenic and somatoform disorders | Mental Disorders | 1 | 0.964 – 1.04 | 0.893 | 3609 | 10708 | exclusion | phecode |
| 303.1 | Dissociative disorder | Mental Disorders | 0.816 | 0.65 – 1.02 | 0.079 | 81 | 902 | exclusion | phecode |
| 303.3 | Psychogenic disorder | Mental Disorders | 1.01 | 0.967 – 1.05 | 0.757 | 3461 | 10598 | exclusion | phecode |
| 303.31 |
Gastrointestinal malfunction arising fromGastrointestinal malfunction arising from mental factors
|
Mental Disorders | 0.928 | 0.813 – 1.06 | 0.272 | 254 | 2564 | exclusion | phecode |
| 303.4 | Somatoform disorder | Mental Disorders | 0.944 | 0.868 – 1.03 | 0.18 | 612 | 6441 | exclusion | phecode |
| 304 | Adjustment reaction | Mental Disorders | 1.02 | 0.97 – 1.07 | 0.469 | 1974 | 11056 | exclusion | phecode |
| 305.2 | Eating disorder | Mental Disorders | 1.13 | 1.03 – 1.24 | 0.0126 | 492 | 4964 | exclusion | phecode |
| 306 | Other mental disorder | Mental Disorders | 1 | 0.935 – 1.08 | 0.923 | 894 | 8060 | exclusion | phecode |
| 306.1 | Mental disorders durring/after pregnancy | Mental Disorders | 1.14 | 1.01 – 1.29 | 0.0305 | 321 | 2277 | exclusion | phecode |
| 306.9 | Tension headache | Mental Disorders | 0.994 | 0.896 – 1.1 | 0.903 | 407 | 4264 | exclusion | phecode |
| 312 | Conduct disorders | Mental Disorders | 1.23 | 1.01 – 1.49 | 0.0355 | 114 | 1328 | exclusion | phecode |
| 312.3 | Impulse control disorder | Mental Disorders | 1.4 | 0.98 – 2 | 0.0648 | 35 | 399 | exclusion | phecode |
| 313 | Pervasive developmental disorders | Mental Disorders | 1.13 | 1.05 – 1.22 | 0.000884 | 787 | 8415 | exclusion | phecode |
| 313.1 | Attention deficit hyperactivity disorder | Mental Disorders | 1.16 | 1.07 – 1.26 | 0.000265 | 685 | 7657 | exclusion | phecode |
| 313.2 | Tics and stuttering | Mental Disorders | 0.994 | 0.712 – 1.39 | 0.973 | 39 | 391 | exclusion | phecode |
| 313.3 | Autism | Mental Disorders | 0.975 | 0.729 – 1.3 | 0.863 | 49 | 384 | exclusion | phecode |
| 315 | Develomental delays and disorders | Mental Disorders | 1.07 | 0.947 – 1.2 | 0.288 | 298 | 3410 | exclusion | phecode |
| 315.1 | Learning disorder | Mental Disorders | 1.11 | 0.831 – 1.48 | 0.481 | 48 | 512 | exclusion | phecode |
| 315.2 | Speech and language disorder | Mental Disorders | 1.03 | 0.864 – 1.22 | 0.76 | 137 | 1281 | exclusion | phecode |
| 316 | Substance addiction and disorders | Mental Disorders | 1.04 | 0.978 – 1.11 | 0.21 | 1103 | 20296 | exclusion | phecode |
| 316.1 | Polyneuropathy due to drugs | Mental Disorders | 0.968 | 0.865 – 1.08 | 0.567 | 341 | 3887 | exclusion | phecode |
| 317 | Alcohol-related disorders | Mental Disorders | 1.03 | 0.947 – 1.11 | 0.518 | 636 | 13775 | exclusion | phecode |
| 317.1 | Alcoholism | Mental Disorders | 1.04 | 0.951 – 1.14 | 0.388 | 527 | 11571 | exclusion | phecode |
| 317.11 | Alcoholic liver damage | Mental Disorders | 1.04 | 0.88 – 1.23 | 0.633 | 141 | 2414 | exclusion | phecode |
| 318 | Tobacco use disorder | Mental Disorders | 0.986 | 0.864 – 1.13 | 0.841 | 224 | 21691 | exclusion | phecode |
| 320 | Meningitis | Neurological | 1.06 | 0.905 – 1.24 | 0.474 | 173 | 1892 | exclusion | phecode |
| 323 | Encephalitis | Neurological | 1.17 | 0.948 – 1.44 | 0.144 | 91 | 887 | exclusion | phecode |
| 323.8 | Encephalitis, non-infectious | Neurological | 1.18 | 0.926 – 1.5 | 0.182 | 73 | 732 | exclusion | phecode |
| 324 | Other CNS infection and poliomyelitis | Neurological | 1.07 | 0.894 – 1.29 | 0.452 | 128 | 1341 | exclusion | phecode |
| 325 |
Phlebitis and thrombophlebitis of intracranialPhlebitis and thrombophlebitis of intracranial venous sinuses
|
Neurological | 1.03 | 0.666 – 1.58 | 0.91 | 21 | 260 | exclusion | phecode |
| 327 | Sleep disorders | Neurological | 1.01 | 0.984 – 1.04 | 0.382 | 7070 | 16536 | exclusion | phecode |
| 327.1 | Hypersomnia | Neurological | 0.978 | 0.918 – 1.04 | 0.486 | 1099 | 9901 | exclusion | phecode |
| 327.3 | Sleep apnea | Neurological | 0.993 | 0.961 – 1.03 | 0.664 | 5123 | 16275 | exclusion | phecode |
| 327.31 | Central/nonobstroctive sleep apnea | Neurological | 0.931 | 0.81 – 1.07 | 0.308 | 215 | 2364 | exclusion | phecode |
| 327.32 | Obstructive sleep apnea | Neurological | 0.987 | 0.953 – 1.02 | 0.472 | 4149 | 15662 | exclusion | phecode |
| 327.4 | Insomnia | Neurological | 1.03 | 0.983 – 1.07 | 0.247 | 2578 | 16053 | exclusion | phecode |
| 327.41 | Organic or persistent insomnia | Neurological | 1 | 0.921 – 1.09 | 0.994 | 641 | 6267 | exclusion | phecode |
| 327.5 | Parasomnia | Neurological | 0.92 | 0.815 – 1.04 | 0.178 | 280 | 2894 | exclusion | phecode |
| 327.6 | Circadian rhythm sleep disorder | Neurological | 1.12 | 0.947 – 1.33 | 0.185 | 151 | 1462 | exclusion | phecode |
| 327.7 | Sleep related movement disorders | Neurological | 1.04 | 0.967 – 1.12 | 0.294 | 825 | 8776 | exclusion | phecode |
| 327.71 | Restless legs syndrome | Neurological | 1.05 | 0.971 – 1.13 | 0.224 | 710 | 7810 | exclusion | phecode |
| 327.72 | Sleep related leg cramps | Neurological | 1.02 | 0.747 – 1.4 | 0.895 | 45 | 415 | exclusion | phecode |
| 331 | Other cerebral degenerations | Neurological | 0.999 | 0.893 – 1.12 | 0.992 | 318 | 3375 | exclusion | phecode |
| 331.1 | Hydrocephalus | Neurological | 0.934 | 0.784 – 1.11 | 0.446 | 137 | 1426 | exclusion | phecode |
| 331.9 | Cerebral degeneration, unspecified | Neurological | 1.05 | 0.903 – 1.22 | 0.525 | 174 | 1871 | exclusion | phecode |
| 332 | Parkinson's disease | Neurological | 0.982 | 0.855 – 1.13 | 0.795 | 229 | 1782 | exclusion | phecode |
| 333 |
Extrapyramidal disease and abnormal movementExtrapyramidal disease and abnormal movement disorders
|
Neurological | 0.993 | 0.938 – 1.05 | 0.812 | 1346 | 13251 | exclusion | phecode |
| 333.1 | Essential tremor | Neurological | 0.97 | 0.869 – 1.08 | 0.586 | 347 | 3351 | exclusion | phecode |
| 333.2 | Myoclonus | Neurological | 0.841 | 0.645 – 1.1 | 0.2 | 58 | 801 | exclusion | phecode |
| 333.4 | Torsion dystonia | Neurological | 0.903 | 0.776 – 1.05 | 0.187 | 189 | 1811 | exclusion | phecode |
| 333.8 | Other degenerative diseases of the basal ganglia | Neurological | 1.15 | 0.831 – 1.58 | 0.407 | 38 | 417 | exclusion | phecode |
| 334 | Degenerative disease of the spinal cord | Neurological | 1.03 | 0.935 – 1.13 | 0.552 | 461 | 5213 | exclusion | phecode |
| 334.1 | Spinocerebellar disease | Neurological | 0.811 | 0.583 – 1.13 | 0.211 | 39 | 390 | exclusion | phecode |
| 334.2 | Anterior horn cell disease | Neurological | 1.22 | 0.932 – 1.6 | 0.147 | 56 | 520 | exclusion | phecode |
| 334.21 | Amyotrophic Lateral Sclerosis | Neurological | 1.14 | 0.819 – 1.58 | 0.438 | 34 | 341 | exclusion | phecode |
| 335 | Multiple sclerosis | Neurological | 0.971 | 0.832 – 1.13 | 0.708 | 163 | 2056 | exclusion | phecode |
| 337 | Disorders of the autonomic nervous system | Neurological | 0.997 | 0.896 – 1.11 | 0.954 | 382 | 3824 | exclusion | phecode |
| 337.1 | Peripheral autonomic neuropathy | Neurological | 1.04 | 0.891 – 1.21 | 0.631 | 176 | 1610 | exclusion | phecode |
| 338 | Pain | Neurological | 1.01 | 0.986 – 1.04 | 0.352 | 9675 | 14055 | exclusion | phecode |
| 338.1 | Acute pain | Neurological | 1.01 | 0.985 – 1.04 | 0.339 | 7370 | 13979 | exclusion | phecode |
| 338.2 | Chronic pain | Neurological | 1.01 | 0.981 – 1.05 | 0.421 | 5006 | 14016 | exclusion | phecode |
| 339 | Other headache syndromes | Neurological | 0.999 | 0.967 – 1.03 | 0.966 | 4792 | 17433 | exclusion | phecode |
| 340 | Migraine | Neurological | 0.986 | 0.949 – 1.02 | 0.463 | 3548 | 15807 | exclusion | phecode |
| 340.1 | Migrain with aura | Neurological | 0.99 | 0.943 – 1.04 | 0.702 | 1929 | 12565 | exclusion | phecode |
| 341 |
Other demyelinating diseases of central nervousOther demyelinating diseases of central nervous system
|
Neurological | 1.03 | 0.785 – 1.34 | 0.856 | 53 | 684 | exclusion | phecode |
| 342 | Hemiplegia | Neurological | 0.919 | 0.802 – 1.05 | 0.223 | 226 | 2332 | exclusion | phecode |
| 343 | Infantile cerebral palsy | Neurological | 1.05 | 0.787 – 1.41 | 0.729 | 51 | 493 | exclusion | phecode |
| 344 | Other paralytic syndromes | Neurological | 1.22 | 1.08 – 1.38 | 0.00113 | 312 | 3416 | exclusion | phecode |
| 345 | Epilepsy, recurrent seizures, convulsions | Neurological | 0.961 | 0.904 – 1.02 | 0.209 | 1132 | 13057 | exclusion | phecode |
| 345.1 | Epilepsy | Neurological | 1.02 | 0.912 – 1.14 | 0.745 | 338 | 3856 | exclusion | phecode |
| 345.11 | Generalized convulsive epilepsy | Neurological | 1.12 | 0.918 – 1.37 | 0.264 | 104 | 1228 | exclusion | phecode |
| 345.12 | Partial epilepsy | Neurological | 1.06 | 0.927 – 1.2 | 0.415 | 243 | 2758 | exclusion | phecode |
| 345.3 | Convulsions | Neurological | 0.974 | 0.914 – 1.04 | 0.413 | 1054 | 12271 | exclusion | phecode |
| 346 |
Abnormal findings on study of brain and/orAbnormal findings on study of brain and/or nervous system
|
Neurological | 1.09 | 0.868 – 1.36 | 0.472 | 84 | 913 | exclusion | phecode |
| 346.1 |
Nonspecific abnormal findings on radiologicalNonspecific abnormal findings on radiological and other examination of skull and head
|
Neurological | 0.953 | 0.879 – 1.03 | 0.238 | 659 | 7168 | exclusion | phecode |
| 346.2 |
Nonspecific abnormal results of function studyNonspecific abnormal results of function study of brain and central nervous system
|
Neurological | 1.02 | 0.77 – 1.36 | 0.877 | 52 | 599 | exclusion | phecode |
| 346.3 |
Nonspecific abnormal findings in cerebrospinalNonspecific abnormal findings in cerebrospinal fluid
|
Neurological | 1.15 | 0.884 – 1.5 | 0.293 | 53 | 570 | exclusion | phecode |
| 347 | Cataplexy and narcolepsy | Neurological | 1.01 | 0.757 – 1.34 | 0.955 | 54 | 554 | exclusion | phecode |
| 348 | Other conditions of brain | Neurological | 0.951 | 0.886 – 1.02 | 0.172 | 834 | 9090 | exclusion | phecode |
| 348.2 | Cerebral edema and compression of brain | Neurological | 0.964 | 0.873 – 1.06 | 0.46 | 443 | 4586 | exclusion | phecode |
| 348.4 | Cerebral cysts | Neurological | 0.846 | 0.7 – 1.02 | 0.0827 | 126 | 1235 | exclusion | phecode |
| 348.7 | Coma | Neurological | 0.99 | 0.809 – 1.21 | 0.918 | 108 | 1162 | exclusion | phecode |
| 348.8 | Encephalopathy, not elsewhere classified | Neurological | 0.977 | 0.878 – 1.09 | 0.667 | 353 | 4164 | exclusion | phecode |
| 348.9 | Other conditions of brain, NOS | Neurological | 0.987 | 0.927 – 1.05 | 0.692 | 1097 | 11578 | exclusion | phecode |
| 349 |
Other and unspecified disorders of the nervousOther and unspecified disorders of the nervous system
|
Neurological | 1 | 0.907 – 1.1 | 1 | 439 | 4765 | exclusion | phecode |
| 350 | Abnormal movement | Neurological | 0.984 | 0.947 – 1.02 | 0.399 | 3187 | 19686 | exclusion | phecode |
| 350.1 | Abnormal involuntary movements | Neurological | 0.989 | 0.938 – 1.04 | 0.677 | 1580 | 14997 | exclusion | phecode |
| 350.2 | Abnormality of gait | Neurological | 0.99 | 0.942 – 1.04 | 0.69 | 1813 | 14754 | exclusion | phecode |
| 350.3 | Lack of coordination | Neurological | 0.936 | 0.855 – 1.02 | 0.154 | 526 | 5248 | exclusion | phecode |
| 350.5 | Abnormal reflex | Neurological | 0.96 | 0.772 – 1.19 | 0.711 | 82 | 986 | exclusion | phecode |
| 350.6 | Disturbances of sensation of smell and taste | Neurological | 0.954 | 0.839 – 1.09 | 0.481 | 252 | 2668 | exclusion | phecode |
| 351 | Other peripheral nerve disorders | Neurological | 0.986 | 0.95 – 1.02 | 0.457 | 3467 | 17687 | exclusion | phecode |
| 352 | Disorders of other cranial nerves | Neurological | 0.971 | 0.905 – 1.04 | 0.421 | 862 | 8527 | exclusion | phecode |
| 352.1 | Trigeminal nerve disorders [CN5] | Neurological | 0.894 | 0.787 – 1.01 | 0.0827 | 252 | 2727 | exclusion | phecode |
| 352.2 | Facial nerve disorders [CN7] | Neurological | 0.966 | 0.871 – 1.07 | 0.511 | 396 | 3903 | exclusion | phecode |
| 353 | Nerve root and plexus disorders | Neurological | 0.977 | 0.932 – 1.03 | 0.347 | 1957 | 16880 | exclusion | phecode |
| 353.1 | Nerve plexus lesions | Neurological | 1.16 | 0.995 – 1.34 | 0.0585 | 193 | 2019 | exclusion | phecode |
| 353.2 | Nerve root lesions | Neurological | 1.04 | 0.787 – 1.38 | 0.78 | 45 | 620 | exclusion | phecode |
| 355 | Complex regional/central pain syndrome | Neurological | 0.962 | 0.838 – 1.1 | 0.578 | 223 | 2753 | exclusion | phecode |
| 355.1 | Chronic pain syndrome | Neurological | 1.03 | 0.915 – 1.15 | 0.649 | 315 | 4325 | exclusion | phecode |
| 356 | Hereditary and idiopathic peripheral neuropathy | Neurological | 1.02 | 0.953 – 1.09 | 0.593 | 1006 | 9846 | exclusion | phecode |
| 357 | Inflammatory and toxic neuropathy | Neurological | 0.965 | 0.914 – 1.02 | 0.198 | 1497 | 14427 | exclusion | phecode |
| 358 | Myoneural disorders | Neurological | 0.986 | 0.896 – 1.08 | 0.766 | 467 | 5766 | exclusion | phecode |
| 358.1 | Myasthenia gravis | Neurological | 0.982 | 0.729 – 1.32 | 0.902 | 47 | 500 | exclusion | phecode |
| 359 | Muscular dystrophies and other myopathies | Neurological | 1.13 | 1.04 – 1.23 | 0.00435 | 617 | 5603 | exclusion | phecode |
| 359.1 | Muscular dystrophies | Neurological | 1.06 | 0.744 – 1.51 | 0.744 | 33 | 338 | exclusion | phecode |
| 359.2 | Myopathy | Neurological | 1.11 | 1.02 – 1.21 | 0.0155 | 599 | 5383 | exclusion | phecode |
| 360 | Disorders of the globe | Sense Organs | 0.86 | 0.668 – 1.11 | 0.24 | 72 | 633 | exclusion | phecode |
| 360.2 | Progressive myopia | Sense Organs | 0.905 | 0.649 – 1.26 | 0.554 | 43 | 314 | exclusion | phecode |
| 361 | Retinal detachments and defects | Sense Organs | 0.991 | 0.888 – 1.11 | 0.869 | 357 | 3316 | exclusion | phecode |
| 361.1 | Retinal detachment with retinal defect | Sense Organs | 1.05 | 0.886 – 1.25 | 0.559 | 138 | 1337 | exclusion | phecode |
| 362 | Other retinal disorders | Sense Organs | 0.985 | 0.935 – 1.04 | 0.585 | 1687 | 10787 | exclusion | phecode |
| 362.2 |
Degeneration of macula and posterior pole ofDegeneration of macula and posterior pole of retina
|
Sense Organs | 0.971 | 0.909 – 1.04 | 0.396 | 999 | 7088 | exclusion | phecode |
| 362.21 | Macular degeneration, dry | Sense Organs | 0.997 | 0.85 – 1.17 | 0.974 | 160 | 1509 | exclusion | phecode |
| 362.22 | Macular degeneration, wet | Sense Organs | 1.26 | 0.967 – 1.64 | 0.0876 | 60 | 504 | exclusion | phecode |
| 362.23 | Cystoid macular degeneration of retina | Sense Organs | 0.982 | 0.85 – 1.13 | 0.803 | 201 | 1776 | exclusion | phecode |
| 362.26 | Macular puckering of retina | Sense Organs | 0.958 | 0.871 – 1.05 | 0.38 | 477 | 3897 | exclusion | phecode |
| 362.27 | Drusen (degenerative) of retina | Sense Organs | 1.07 | 0.93 – 1.22 | 0.357 | 221 | 2160 | exclusion | phecode |
| 362.29 | Macular degeneration (senile) of retina NOS | Sense Organs | 0.964 | 0.897 – 1.04 | 0.313 | 866 | 6377 | exclusion | phecode |
| 362.3 | Other nondiabetic retinopathy | Sense Organs | 1.03 | 0.93 – 1.13 | 0.606 | 447 | 3916 | exclusion | phecode |
| 362.31 | Separation of retinal layers | Sense Organs | 1.13 | 0.974 – 1.32 | 0.106 | 188 | 1856 | exclusion | phecode |
| 362.4 | Retinal vascular changes and abnomalities | Sense Organs | 1.02 | 0.905 – 1.15 | 0.75 | 307 | 2743 | exclusion | phecode |
| 362.6 | Peripheral retinal degenerations | Sense Organs | 1.01 | 0.872 – 1.17 | 0.904 | 209 | 1862 | exclusion | phecode |
| 362.7 | Hereditary retinal dystrophies | Sense Organs | 0.992 | 0.819 – 1.2 | 0.934 | 114 | 991 | exclusion | phecode |
| 362.8 | Retinal hemorrhage/ischemia | Sense Organs | 1.05 | 0.874 – 1.25 | 0.626 | 124 | 1186 | exclusion | phecode |
| 362.9 | Retinal edema | Sense Organs | 0.977 | 0.83 – 1.15 | 0.777 | 159 | 1366 | exclusion | phecode |
| 363 |
Chorioretinal inflammations, scars, and otherChorioretinal inflammations, scars, and other disorders of choroid
|
Sense Organs | 1.05 | 0.911 – 1.2 | 0.521 | 226 | 2192 | exclusion | phecode |
| 363.3 | Chorioretinal scars | Sense Organs | 1.13 | 0.955 – 1.34 | 0.155 | 146 | 1478 | exclusion | phecode |
| 364 | Corneal opacity and other disorders of cornea | Sense Organs | 1.11 | 1.02 – 1.21 | 0.0191 | 595 | 5230 | exclusion | phecode |
| 364.1 | Corneal opacity | Sense Organs | 1.05 | 0.906 – 1.21 | 0.538 | 200 | 1892 | exclusion | phecode |
| 364.2 | Corneal edema | Sense Organs | 0.956 | 0.74 – 1.24 | 0.733 | 65 | 546 | exclusion | phecode |
| 364.4 | Corneal degenerations | Sense Organs | 1.2 | 1.04 – 1.38 | 0.012 | 218 | 2032 | exclusion | phecode |
| 364.41 | Keratoconus | Sense Organs | 0.882 | 0.647 – 1.2 | 0.426 | 50 | 389 | exclusion | phecode |
| 364.5 | Corneal dystrophy | Sense Organs | 1.08 | 0.948 – 1.24 | 0.241 | 255 | 2188 | exclusion | phecode |
| 364.51 | Fuchs' dystrophy | Sense Organs | 1.02 | 0.849 – 1.22 | 0.855 | 138 | 1147 | exclusion | phecode |
| 364.9 | Cornea replaced by transplant | Sense Organs | 1.15 | 0.862 – 1.53 | 0.347 | 46 | 374 | exclusion | phecode |
| 365 | Glaucoma | Sense Organs | 1 | 0.947 – 1.07 | 0.87 | 1271 | 10104 | exclusion | phecode |
| 365.1 | Open-angle glaucoma | Sense Organs | 1 | 0.899 – 1.11 | 0.995 | 365 | 2965 | exclusion | phecode |
| 365.11 | Primary open angle glaucoma | Sense Organs | 1.06 | 0.918 – 1.22 | 0.436 | 198 | 1662 | exclusion | phecode |
| 365.2 | Primary angle-closure glaucoma | Sense Organs | 1.24 | 1.02 – 1.5 | 0.0281 | 118 | 1138 | exclusion | phecode |
| 366 | Cataract | Sense Organs | 0.992 | 0.954 – 1.03 | 0.667 | 4034 | 13632 | exclusion | phecode |
| 366.1 | Nonsenile Cataract | Sense Organs | 1.07 | 0.879 – 1.31 | 0.484 | 105 | 982 | exclusion | phecode |
| 366.2 | Senile cataract | Sense Organs | 1 | 0.96 – 1.05 | 0.865 | 2626 | 11964 | exclusion | phecode |
| 367 |
Disorders of refraction and accommodationDisorders of refraction and accommodation; blindness and low vision
|
Sense Organs | 1.03 | 0.995 – 1.06 | 0.1 | 4805 | 18910 | exclusion | phecode |
| 367.1 | Myopia | Sense Organs | 1.02 | 0.976 – 1.06 | 0.443 | 2918 | 17403 | exclusion | phecode |
| 367.2 | Astigmatism | Sense Organs | 1.01 | 0.969 – 1.06 | 0.573 | 2319 | 15997 | exclusion | phecode |
| 367.8 | Hypermetropia | Sense Organs | 0.995 | 0.931 – 1.06 | 0.883 | 1004 | 9106 | exclusion | phecode |
| 367.9 | Blindness and low vision | Sense Organs | 1.05 | 0.963 – 1.14 | 0.278 | 572 | 5904 | exclusion | phecode |
| 368 | Visual disturbances | Sense Organs | 1 | 0.965 – 1.05 | 0.819 | 2845 | 19967 | exclusion | phecode |
| 368.1 | Amblyopia | Sense Organs | 1.09 | 0.97 – 1.22 | 0.149 | 346 | 3239 | exclusion | phecode |
| 368.2 | Diplopia and disorders of binocular vision | Sense Organs | 1.01 | 0.924 – 1.11 | 0.808 | 518 | 5215 | exclusion | phecode |
| 368.3 | Anisometropia | Sense Organs | 1.12 | 0.929 – 1.34 | 0.237 | 135 | 1083 | exclusion | phecode |
| 368.4 | Visual field defects | Sense Organs | 0.941 | 0.858 – 1.03 | 0.198 | 501 | 5264 | exclusion | phecode |
| 368.9 | Subjective visual disturbances | Sense Organs | 0.924 | 0.844 – 1.01 | 0.0875 | 526 | 5301 | exclusion | phecode |
| 368.91 | Psychophysical visual disturbances | Sense Organs | 0.843 | 0.628 – 1.13 | 0.253 | 49 | 537 | exclusion | phecode |
| 369 | Infection of the eye | Sense Organs | 1.04 | 0.986 – 1.09 | 0.159 | 1875 | 14633 | exclusion | phecode |
| 369.2 | Eye infection, viral | Sense Organs | 1.04 | 0.926 – 1.18 | 0.476 | 296 | 2553 | exclusion | phecode |
| 369.5 | Conjunctivitis, infectious | Sense Organs | 1.03 | 0.977 – 1.09 | 0.275 | 1617 | 12999 | exclusion | phecode |
| 370 | Keratitis | Sense Organs | 1.01 | 0.933 – 1.09 | 0.828 | 707 | 6590 | exclusion | phecode |
| 370.1 | Corneal ulcer | Sense Organs | 1.11 | 0.911 – 1.34 | 0.308 | 121 | 1114 | exclusion | phecode |
| 370.2 | Superficial keratitis | Sense Organs | 1.04 | 0.924 – 1.17 | 0.513 | 305 | 2689 | exclusion | phecode |
| 370.3 | Keratoconjunctivitis | Sense Organs | 1.08 | 0.956 – 1.21 | 0.225 | 311 | 3110 | exclusion | phecode |
| 370.31 | Keratoconjunctivitis sicca | Sense Organs | 0.991 | 0.803 – 1.22 | 0.934 | 92 | 846 | exclusion | phecode |
| 371 | Inflammation of the eye | Sense Organs | 1.05 | 1 – 1.09 | 0.0522 | 2309 | 15787 | exclusion | phecode |
| 371.1 | Uveitis, noninfectious or NOS | Sense Organs | 1.02 | 0.895 – 1.16 | 0.774 | 262 | 2624 | exclusion | phecode |
| 371.2 | Conjunctivitis, noninfectious | Sense Organs | 1.06 | 0.969 – 1.16 | 0.204 | 528 | 4606 | exclusion | phecode |
| 371.21 | Allergic conjunctivitis | Sense Organs | 1.04 | 0.945 – 1.15 | 0.41 | 448 | 3887 | exclusion | phecode |
| 371.3 | Inflammation of eyelids | Sense Organs | 1.06 | 1.01 – 1.11 | 0.0296 | 1744 | 12985 | exclusion | phecode |
| 371.33 | Noninfectious dermatoses of eyelid | Sense Organs | 1.2 | 0.947 – 1.52 | 0.132 | 80 | 700 | exclusion | phecode |
| 372 | Disorders of conjunctiva | Sense Organs | 1.03 | 0.945 – 1.13 | 0.472 | 543 | 5112 | exclusion | phecode |
| 374 | Other disorders of eyelids | Sense Organs | 1.02 | 0.968 – 1.08 | 0.41 | 1418 | 11472 | exclusion | phecode |
| 374.1 | Ectropion or entropion | Sense Organs | 1.02 | 0.882 – 1.17 | 0.809 | 195 | 1844 | exclusion | phecode |
| 374.2 | Lagophthalmos | Sense Organs | 1.15 | 0.943 – 1.41 | 0.167 | 99 | 1128 | exclusion | phecode |
| 374.3 | Ptosis of eyelid | Sense Organs | 1.03 | 0.94 – 1.13 | 0.522 | 518 | 5012 | exclusion | phecode |
| 374.6 | Dermatochalasis | Sense Organs | 0.998 | 0.906 – 1.1 | 0.96 | 464 | 4466 | exclusion | phecode |
| 375 | Disorders of lacrimal system | Sense Organs | 1.03 | 0.979 – 1.08 | 0.258 | 1864 | 12654 | exclusion | phecode |
| 375.1 | Dry eyes | Sense Organs | 1.06 | 1.01 – 1.11 | 0.0232 | 2073 | 12978 | exclusion | phecode |
| 375.2 | Epiphora | Sense Organs | 1.2 | 1.04 – 1.39 | 0.0116 | 204 | 2076 | exclusion | phecode |
| 376 | Disorders of the orbit | Sense Organs | 1.05 | 0.901 – 1.23 | 0.51 | 175 | 1715 | exclusion | phecode |
| 377 | Disorders of optic nerve and visual pathways | Sense Organs | 0.999 | 0.908 – 1.1 | 0.985 | 461 | 4448 | exclusion | phecode |
| 377.1 | Optic atrophy | Sense Organs | 1.06 | 0.901 – 1.26 | 0.464 | 149 | 1384 | exclusion | phecode |
| 377.3 | Optic neuritis/neuropathy | Sense Organs | 1.02 | 0.903 – 1.15 | 0.747 | 281 | 2845 | exclusion | phecode |
| 378 |
Strabismus and other disorders of binocular eyeStrabismus and other disorders of binocular eye movements
|
Sense Organs | 1.05 | 0.968 – 1.14 | 0.241 | 639 | 6127 | exclusion | phecode |
| 378.1 | Strabismus (not specified as paralytic) | Sense Organs | 1.11 | 1 – 1.23 | 0.042 | 420 | 4040 | exclusion | phecode |
| 378.2 | Nystagmus and other irregular eye movements | Sense Organs | 0.881 | 0.689 – 1.13 | 0.311 | 79 | 850 | exclusion | phecode |
| 378.5 | Paralytic strabismus | Sense Organs | 1.03 | 0.88 – 1.21 | 0.7 | 176 | 1668 | exclusion | phecode |
| 379 | Other disorders of eye | Sense Organs | 1.02 | 0.978 – 1.07 | 0.349 | 2587 | 14464 | exclusion | phecode |
| 379.1 | Scleritis and episcleritis | Sense Organs | 0.942 | 0.771 – 1.15 | 0.559 | 100 | 931 | exclusion | phecode |
| 379.2 | Disorders of vitreous body | Sense Organs | 1.01 | 0.956 – 1.06 | 0.839 | 1847 | 10880 | exclusion | phecode |
| 379.3 | Aphakia and other disorders of lens | Sense Organs | 1.14 | 0.893 – 1.46 | 0.287 | 66 | 575 | exclusion | phecode |
| 379.4 | Anomalies of pupillary function | Sense Organs | 1.01 | 0.847 – 1.21 | 0.89 | 131 | 1336 | exclusion | phecode |
| 379.5 | Disorders of iris and ciliary body | Sense Organs | 0.993 | 0.84 – 1.17 | 0.934 | 148 | 1374 | exclusion | phecode |
| 379.51 | Pigmentary iris degeneration | Sense Organs | 1.05 | 0.766 – 1.45 | 0.749 | 43 | 318 | exclusion | phecode |
| 379.9 | Pain, swelling or discharge of eye | Sense Organs | 0.958 | 0.878 – 1.05 | 0.339 | 574 | 5696 | exclusion | phecode |
| 380 | Disorders of external ear | Sense Organs | 0.955 | 0.898 – 1.02 | 0.14 | 1148 | 9818 | exclusion | phecode |
| 380.1 | Otitis externa | Sense Organs | 1.05 | 0.974 – 1.13 | 0.201 | 745 | 7452 | exclusion | phecode |
| 380.4 | Impacted cerumen | Sense Organs | 0.959 | 0.906 – 1.02 | 0.151 | 1365 | 11422 | exclusion | phecode |
| 381 | Otitis media and Eustachian tube disorders | Sense Organs | 0.992 | 0.95 – 1.04 | 0.717 | 2360 | 18807 | exclusion | phecode |
| 381.1 | Otitis media | Sense Organs | 0.996 | 0.946 – 1.05 | 0.886 | 1687 | 15714 | exclusion | phecode |
| 381.11 | Suppurative and unspecified otitis media | Sense Organs | 0.995 | 0.941 – 1.05 | 0.873 | 1424 | 13583 | exclusion | phecode |
| 381.2 | Eustachian tube disorders | Sense Organs | 0.977 | 0.916 – 1.04 | 0.485 | 1043 | 9315 | exclusion | phecode |
| 381.3 | Mastoiditis & related conditions | Sense Organs | 0.867 | 0.681 – 1.1 | 0.248 | 68 | 792 | exclusion | phecode |
| 381.9 | Otorrhea | Sense Organs | 1.07 | 0.909 – 1.25 | 0.428 | 167 | 1879 | exclusion | phecode |
| 382 | Otalgia | Sense Organs | 0.992 | 0.929 – 1.06 | 0.814 | 1000 | 9962 | exclusion | phecode |
| 383 | Otosclerosis | Sense Organs | 0.946 | 0.737 – 1.21 | 0.66 | 67 | 645 | exclusion | phecode |
| 384 | Other disorders of tympanic membrane | Sense Organs | 1.13 | 0.992 – 1.28 | 0.0663 | 271 | 2730 | exclusion | phecode |
| 384.1 | Myringitis | Sense Organs | 1.29 | 0.86 – 1.92 | 0.22 | 27 | 276 | exclusion | phecode |
| 384.4 | Perforation of tympanic membrane | Sense Organs | 1.13 | 0.981 – 1.3 | 0.0908 | 207 | 2113 | exclusion | phecode |
| 385 | Other disorders of middle ear and mastoid | Sense Organs | 0.972 | 0.841 – 1.12 | 0.705 | 196 | 2222 | exclusion | phecode |
| 385.3 | Cholesteatoma | Sense Organs | 0.92 | 0.765 – 1.11 | 0.38 | 125 | 1400 | exclusion | phecode |
| 385.5 |
Tympanosclerosis and middle ear disease relatedTympanosclerosis and middle ear disease related to otitis media
|
Sense Organs | 0.913 | 0.698 – 1.19 | 0.505 | 59 | 624 | exclusion | phecode |
| 386 |
Vertiginous syndromes and other disorders ofVertiginous syndromes and other disorders of vestibular system
|
Sense Organs | 1.02 | 0.953 – 1.09 | 0.6 | 997 | 9029 | exclusion | phecode |
| 386.1 | Meniere's disease | Sense Organs | 1.17 | 1 – 1.36 | 0.0483 | 182 | 1574 | exclusion | phecode |
| 386.2 | Peripheral or central vertigo | Sense Organs | 1.04 | 0.964 – 1.11 | 0.341 | 846 | 7648 | exclusion | phecode |
| 386.21 | Central origin vertigo | Sense Organs | 0.997 | 0.918 – 1.08 | 0.937 | 645 | 5899 | exclusion | phecode |
| 386.3 | Labyrinthitis | Sense Organs | 0.984 | 0.914 – 1.06 | 0.679 | 793 | 7261 | exclusion | phecode |
| 386.9 |
Dizziness and giddiness (Light-headedness andDizziness and giddiness (Light-headedness and vertigo)
|
Sense Organs | 0.986 | 0.95 – 1.02 | 0.448 | 3459 | 19265 | exclusion | phecode |
| 388 | Other disorders of ear | Sense Organs | 1.06 | 0.971 – 1.17 | 0.182 | 516 | 4803 | exclusion | phecode |
| 389 | Hearing loss | Sense Organs | 0.999 | 0.964 – 1.04 | 0.973 | 3914 | 19486 | exclusion | phecode |
| 389.1 | Sensorineural hearing loss | Sense Organs | 1.02 | 0.971 – 1.07 | 0.456 | 2003 | 14175 | exclusion | phecode |
| 389.2 | Conductive hearing loss | Sense Organs | 0.983 | 0.896 – 1.08 | 0.717 | 485 | 4774 | exclusion | phecode |
| 389.3 | Degenerative and vascular disorders of ear | Sense Organs | 0.993 | 0.808 – 1.22 | 0.948 | 90 | 840 | exclusion | phecode |
| 389.4 | Tinnitus | Sense Organs | 1 | 0.946 – 1.07 | 0.894 | 1219 | 10759 | exclusion | phecode |
| 389.5 | Disorders of acoustic nerve | Sense Organs | 0.987 | 0.777 – 1.25 | 0.915 | 75 | 629 | exclusion | phecode |
| 394 | Rheumatic disease of the heart valves | Circulatory System | 0.924 | 0.851 – 1 | 0.0565 | 648 | 6218 | exclusion | phecode |
| 394.1 | Mitral valve stenosis and aortic valve stenosis | Circulatory System | 0.975 | 0.822 – 1.16 | 0.774 | 148 | 1512 | exclusion | phecode |
| 394.2 | Mitral valve disease | Circulatory System | 0.919 | 0.797 – 1.06 | 0.245 | 215 | 2087 | exclusion | phecode |
| 394.3 | Aortic valve disease | Circulatory System | 0.828 | 0.626 – 1.1 | 0.188 | 52 | 732 | exclusion | phecode |
| 394.4 | Acute rheumatic heart disease | Circulatory System | 1.39 | 0.907 – 2.14 | 0.131 | 19 | 250 | exclusion | phecode |
| 394.7 | Disease of tricuspid valve | Circulatory System | 0.857 | 0.756 – 0.971 | 0.0151 | 266 | 2635 | exclusion | phecode |
| 395 | Heart valve disorders | Circulatory System | 1 | 0.951 – 1.05 | 0.986 | 1790 | 13757 | exclusion | phecode |
| 395.1 | Nonrheumatic mitral valve disorders | Circulatory System | 0.971 | 0.911 – 1.04 | 0.377 | 1067 | 9715 | exclusion | phecode |
| 395.2 | Nonrheumatic aortic valve disorders | Circulatory System | 0.977 | 0.909 – 1.05 | 0.531 | 824 | 7730 | exclusion | phecode |
| 395.3 | Nonrheumatic tricuspid valve disorders | Circulatory System | 0.939 | 0.819 – 1.08 | 0.372 | 227 | 2252 | exclusion | phecode |
| 395.4 | Nonrheumatic pulmonary valve disorders | Circulatory System | 0.731 | 0.55 – 0.971 | 0.0308 | 56 | 558 | exclusion | phecode |
| 395.6 | Heart valve replaced | Circulatory System | 0.962 | 0.874 – 1.06 | 0.436 | 461 | 4705 | exclusion | phecode |
| 396 | Abnormal heart sounds | Circulatory System | 1.01 | 0.968 – 1.06 | 0.616 | 2371 | 17086 | exclusion | phecode |
| 401 | Hypertension | Circulatory System | 1.01 | 0.982 – 1.04 | 0.452 | 10452 | 13219 | exclusion | phecode |
| 401.1 | Essential hypertension | Circulatory System | 1.01 | 0.982 – 1.04 | 0.441 | 10373 | 13216 | exclusion | phecode |
| 401.2 | Hypertensive heart and/or renal disease | Circulatory System | 1.02 | 0.958 – 1.08 | 0.574 | 1404 | 7717 | exclusion | phecode |
| 401.21 | Hypertensive heart disease | Circulatory System | 1.03 | 0.924 – 1.15 | 0.6 | 358 | 3332 | exclusion | phecode |
| 401.22 | Hypertensive chronic kidney disease | Circulatory System | 1.02 | 0.949 – 1.09 | 0.657 | 1050 | 6855 | exclusion | phecode |
| 401.3 | Other hypertensive complications | Circulatory System | 0.975 | 0.916 – 1.04 | 0.426 | 1234 | 8468 | exclusion | phecode |
| 411 | Ischemic Heart Disease | Circulatory System | 0.993 | 0.954 – 1.03 | 0.726 | 3243 | 15645 | exclusion | phecode |
| 411.1 | Unstable angina (intermediate coronary syndrome) | Circulatory System | 1.05 | 0.94 – 1.18 | 0.373 | 328 | 4087 | exclusion | phecode |
| 411.2 | Myocardial infarction | Circulatory System | 1.02 | 0.958 – 1.09 | 0.547 | 1151 | 10892 | exclusion | phecode |
| 411.3 | Angina pectoris | Circulatory System | 0.965 | 0.899 – 1.03 | 0.313 | 898 | 9055 | exclusion | phecode |
| 411.4 | Coronary atherosclerosis | Circulatory System | 0.979 | 0.937 – 1.02 | 0.339 | 2732 | 14048 | exclusion | phecode |
| 411.41 | Aneurysm and dissection of heart | Circulatory System | 1.11 | 0.848 – 1.44 | 0.459 | 59 | 714 | exclusion | phecode |
| 411.8 |
Other chronic ischemic heart diseaseOther chronic ischemic heart disease, unspecified
|
Circulatory System | 0.953 | 0.908 – 1 | 0.0493 | 2178 | 13075 | exclusion | phecode |
| 411.9 |
Other acute and subacute forms of ischemicOther acute and subacute forms of ischemic heart disease
|
Circulatory System | 0.919 | 0.785 – 1.08 | 0.295 | 165 | 1961 | exclusion | phecode |
| 414 | Other forms of chronic heart disease | Circulatory System | 0.941 | 0.887 – 0.999 | 0.0455 | 1266 | 11397 | exclusion | phecode |
| 414.2 | ASCVD | Circulatory System | 0.843 | 0.745 – 0.952 | 0.00609 | 288 | 3242 | exclusion | phecode |
| 415 | Pulmonary heart disease | Circulatory System | 0.958 | 0.906 – 1.01 | 0.133 | 1398 | 14479 | exclusion | phecode |
| 415.1 | Acute pulmonary heart disease | Circulatory System | 0.999 | 0.928 – 1.07 | 0.972 | 811 | 8994 | exclusion | phecode |
| 415.11 | Pulmonary embolism and infarction, acute | Circulatory System | 1 | 0.931 – 1.08 | 0.962 | 806 | 8972 | exclusion | phecode |
| 415.2 | Chronic pulmonary heart disease | Circulatory System | 0.957 | 0.887 – 1.03 | 0.268 | 713 | 8282 | exclusion | phecode |
| 415.21 | Primary pulmonary hypertension | Circulatory System | 0.955 | 0.843 – 1.08 | 0.474 | 261 | 3277 | exclusion | phecode |
| 416 | Cardiomegaly | Circulatory System | 1.04 | 0.958 – 1.13 | 0.334 | 604 | 5921 | exclusion | phecode |
| 418 | Nonspecific chest pain | Circulatory System | 0.994 | 0.965 – 1.02 | 0.718 | 6018 | 17622 | exclusion | phecode |
| 418.1 | Precordial pain | Circulatory System | 0.992 | 0.915 – 1.08 | 0.843 | 660 | 6701 | exclusion | phecode |
| 420 | Carditis | Circulatory System | 1.01 | 0.934 – 1.09 | 0.827 | 714 | 7380 | exclusion | phecode |
| 420.1 | Myocarditis | Circulatory System | 1.13 | 0.821 – 1.55 | 0.461 | 41 | 495 | exclusion | phecode |
| 420.2 | Pericarditis | Circulatory System | 1.01 | 0.907 – 1.12 | 0.896 | 390 | 3967 | exclusion | phecode |
| 420.21 | Acute pericarditis | Circulatory System | 1.04 | 0.818 – 1.32 | 0.758 | 77 | 870 | exclusion | phecode |
| 420.22 | Chronic pericarditis | Circulatory System | 0.962 | 0.726 – 1.28 | 0.79 | 48 | 573 | exclusion | phecode |
| 420.3 | Endocarditis | Circulatory System | 0.968 | 0.865 – 1.08 | 0.564 | 331 | 3482 | exclusion | phecode |
| 425 | Cardiomyopathy | Circulatory System | 1.02 | 0.951 – 1.1 | 0.566 | 860 | 9208 | exclusion | phecode |
| 425.1 | Primary/intrinsic cardiomyopathies | Circulatory System | 1.02 | 0.95 – 1.1 | 0.569 | 818 | 8746 | exclusion | phecode |
| 425.11 | Hypertrophic obstructive cardiomyopathy | Circulatory System | 1.34 | 1.07 – 1.67 | 0.00942 | 93 | 987 | exclusion | phecode |
| 425.12 | Other hypertrophic cardiomyopathy | Circulatory System | 1.23 | 0.994 – 1.52 | 0.0573 | 98 | 966 | exclusion | phecode |
| 425.2 | Secondary/extrinsic cardiomyopathies | Circulatory System | 1.01 | 0.853 – 1.2 | 0.896 | 152 | 1533 | exclusion | phecode |
| 425.8 | Other cardiomyopathy | Circulatory System | 1.18 | 0.855 – 1.63 | 0.315 | 42 | 470 | exclusion | phecode |
| 426 | Cardiac conduction disorders | Circulatory System | 1.01 | 0.978 – 1.05 | 0.506 | 5555 | 13595 | exclusion | phecode |
| 426.2 | Atrioventricular [AV] block | Circulatory System | 1 | 0.93 – 1.08 | 0.929 | 794 | 5503 | exclusion | phecode |
| 426.21 | First degree AV block | Circulatory System | 1.01 | 0.918 – 1.1 | 0.879 | 531 | 4097 | exclusion | phecode |
| 426.22 | Mobitz II AV block | Circulatory System | 1.01 | 0.687 – 1.48 | 0.969 | 30 | 248 | exclusion | phecode |
| 426.23 | Second degree AV block | Circulatory System | 0.893 | 0.724 – 1.1 | 0.288 | 94 | 855 | exclusion | phecode |
| 426.24 | Atrioventricular block, complete | Circulatory System | 0.959 | 0.827 – 1.11 | 0.575 | 192 | 1775 | exclusion | phecode |
| 426.25 | Other heart block | Circulatory System | 0.929 | 0.751 – 1.15 | 0.494 | 90 | 818 | exclusion | phecode |
| 426.3 | Bundle branch block | Circulatory System | 0.973 | 0.908 – 1.04 | 0.443 | 929 | 6824 | exclusion | phecode |
| 426.31 | Right bundle branch block | Circulatory System | 0.949 | 0.868 – 1.04 | 0.247 | 549 | 5104 | exclusion | phecode |
| 426.32 | Left bundle branch block | Circulatory System | 0.969 | 0.875 – 1.07 | 0.549 | 407 | 3796 | exclusion | phecode |
| 426.4 | Anomalous atrioventricular excitation | Circulatory System | 0.911 | 0.681 – 1.22 | 0.526 | 48 | 428 | exclusion | phecode |
| 426.7 | Abnormal electrocardiogram [ECG] [EKG] | Circulatory System | 1.01 | 0.977 – 1.05 | 0.507 | 4819 | 13379 | exclusion | phecode |
| 426.8 | Other cardiac conduction disorders | Circulatory System | 0.979 | 0.866 – 1.11 | 0.74 | 284 | 3258 | exclusion | phecode |
| 426.9 | Cardiac pacemaker/device in situ | Circulatory System | 1.02 | 0.945 – 1.11 | 0.558 | 690 | 5461 | exclusion | phecode |
| 426.91 | Cardiac pacemaker in situ | Circulatory System | 0.978 | 0.887 – 1.08 | 0.662 | 465 | 3741 | exclusion | phecode |
| 426.92 | Cardiac defibrillator in situ | Circulatory System | 1.03 | 0.917 – 1.16 | 0.616 | 315 | 3312 | exclusion | phecode |
| 427 | Cardiac dysrhythmias | Circulatory System | 1.01 | 0.977 – 1.04 | 0.687 | 8217 | 13826 | exclusion | phecode |
| 427.1 | Paroxysmal tachycardia, unspecified | Circulatory System | 1.01 | 0.95 – 1.08 | 0.725 | 1137 | 9218 | exclusion | phecode |
| 427.11 | Paroxysmal supraventricular tachycardia | Circulatory System | 1.01 | 0.94 – 1.09 | 0.734 | 786 | 7215 | exclusion | phecode |
| 427.12 | Paroxysmal ventricular tachycardia | Circulatory System | 1.03 | 0.932 – 1.13 | 0.595 | 474 | 4690 | exclusion | phecode |
| 427.2 | Atrial fibrillation and flutter | Circulatory System | 1.01 | 0.966 – 1.07 | 0.566 | 2248 | 9327 | exclusion | phecode |
| 427.21 | Atrial fibrillation | Circulatory System | 1.01 | 0.963 – 1.06 | 0.644 | 2185 | 9171 | exclusion | phecode |
| 427.22 | Atrial flutter | Circulatory System | 1.01 | 0.933 – 1.09 | 0.836 | 743 | 5176 | exclusion | phecode |
| 427.3 | Other specified cardiac dysrhythmias | Circulatory System | 0.984 | 0.948 – 1.02 | 0.4 | 3951 | 13697 | exclusion | phecode |
| 427.4 | Cardiac arrest and ventricular fibrillation | Circulatory System | 0.944 | 0.822 – 1.08 | 0.411 | 222 | 2472 | exclusion | phecode |
| 427.41 | Ventricular fibrillation and flutter | Circulatory System | 1.02 | 0.825 – 1.26 | 0.865 | 96 | 962 | exclusion | phecode |
| 427.42 | Cardiac arrest | Circulatory System | 0.934 | 0.795 – 1.1 | 0.41 | 162 | 1902 | exclusion | phecode |
| 427.5 | Arrhythmia (cardiac) NOS | Circulatory System | 1.01 | 0.97 – 1.05 | 0.653 | 3259 | 13625 | exclusion | phecode |
| 427.6 | Premature beats | Circulatory System | 1.03 | 0.963 – 1.1 | 0.414 | 1102 | 8084 | exclusion | phecode |
| 427.61 | Supraventricular premature beats | Circulatory System | 1.11 | 0.991 – 1.25 | 0.0693 | 309 | 3027 | exclusion | phecode |
| 427.7 | Tachycardia NOS | Circulatory System | 1.01 | 0.963 – 1.05 | 0.763 | 2401 | 13666 | exclusion | phecode |
| 427.8 | Sinoatrial node dysfunction (Bradycardia) | Circulatory System | 0.976 | 0.882 – 1.08 | 0.634 | 415 | 3495 | exclusion | phecode |
| 427.9 | Palpitations | Circulatory System | 1.02 | 0.971 – 1.06 | 0.485 | 2386 | 12991 | exclusion | phecode |
| 428 | Congestive heart failure; nonhypertensive | Circulatory System | 0.986 | 0.935 – 1.04 | 0.589 | 1654 | 11748 | exclusion | phecode |
| 428.1 | Congestive heart failure (CHF) NOS | Circulatory System | 0.983 | 0.929 – 1.04 | 0.554 | 1423 | 11084 | exclusion | phecode |
| 428.2 | Heart failure NOS | Circulatory System | 0.975 | 0.921 – 1.03 | 0.392 | 1397 | 10669 | exclusion | phecode |
| 428.3 |
Heart failure with reduced EF [Systolic orHeart failure with reduced EF [Systolic or combined heart failure]
|
Circulatory System | 0.948 | 0.874 – 1.03 | 0.192 | 661 | 6860 | exclusion | phecode |
| 428.4 |
Heart failure with preserved EF [DiastolicHeart failure with preserved EF [Diastolic heart failure]
|
Circulatory System | 0.949 | 0.873 – 1.03 | 0.213 | 611 | 6343 | exclusion | phecode |
| 429 |
Ill-defined descriptions and complications ofIll-defined descriptions and complications of heart disease
|
Circulatory System | 1.01 | 0.982 – 1.04 | 0.403 | 5894 | 17137 | exclusion | phecode |
| 429.1 | Heart transplant/surgery | Circulatory System | 1.06 | 0.975 – 1.16 | 0.165 | 553 | 5525 | exclusion | phecode |
| 429.2 | Abnormal function study of cardiovascular system | Circulatory System | 1 | 0.961 – 1.04 | 0.923 | 2801 | 14918 | exclusion | phecode |
| 429.3 | Symptoms involving cardiovascular system | Circulatory System | 1.01 | 0.975 – 1.04 | 0.643 | 4535 | 17076 | exclusion | phecode |
| 429.9 | Cardiac complications, not elsewhere classified | Circulatory System | 0.96 | 0.852 – 1.08 | 0.496 | 297 | 3264 | exclusion | phecode |
| 430 | Intracranial hemorrhage | Circulatory System | 1.04 | 0.937 – 1.16 | 0.432 | 348 | 3777 | exclusion | phecode |
| 430.1 | Subarachnoid hemorrhage | Circulatory System | 1.04 | 0.844 – 1.29 | 0.704 | 90 | 1208 | exclusion | phecode |
| 430.2 | Intracerebral hemorrhage | Circulatory System | 1.08 | 0.923 – 1.26 | 0.347 | 171 | 1787 | exclusion | phecode |
| 430.3 | Subdural hemorrhage | Circulatory System | 0.848 | 0.705 – 1.02 | 0.0793 | 116 | 1286 | exclusion | phecode |
| 433 | Cerebrovascular disease | Circulatory System | 0.99 | 0.944 – 1.04 | 0.667 | 2018 | 16077 | exclusion | phecode |
| 433.1 | Occlusion and stenosis of precerebral arteries | Circulatory System | 0.978 | 0.9 – 1.06 | 0.592 | 605 | 7586 | exclusion | phecode |
| 433.11 |
Occlusion of cerebral arteries, with cerebralOcclusion of cerebral arteries, with cerebral infarction
|
Circulatory System | 1 | 0.818 – 1.22 | 0.996 | 101 | 1166 | exclusion | phecode |
| 433.12 | Cerebral atherosclerosis | Circulatory System | 1.68 | 1.11 – 2.53 | 0.0135 | 25 | 360 | exclusion | phecode |
| 433.2 | Occlusion of cerebral arteries | Circulatory System | 1.02 | 0.957 – 1.1 | 0.486 | 942 | 10470 | exclusion | phecode |
| 433.21 |
Cerebral artery occlusion, with cerebralCerebral artery occlusion, with cerebral infarction
|
Circulatory System | 1.03 | 0.961 – 1.1 | 0.411 | 905 | 10166 | exclusion | phecode |
| 433.3 | Cerebral ischemia | Circulatory System | 0.984 | 0.924 – 1.05 | 0.624 | 1086 | 11051 | exclusion | phecode |
| 433.31 | Transient cerebral ischemia | Circulatory System | 0.977 | 0.914 – 1.05 | 0.5 | 944 | 10022 | exclusion | phecode |
| 433.5 | Cerebral aneurysm | Circulatory System | 1.06 | 0.891 – 1.26 | 0.517 | 135 | 2401 | exclusion | phecode |
| 433.6 | Acute, but ill-defined cerebrovascular disease | Circulatory System | 1.09 | 0.941 – 1.27 | 0.249 | 187 | 2173 | exclusion | phecode |
| 433.8 | Late effects of cerebrovascular disease | Circulatory System | 1.1 | 0.977 – 1.25 | 0.112 | 279 | 3343 | exclusion | phecode |
| 440 | Atherosclerosis | Circulatory System | 0.998 | 0.927 – 1.07 | 0.952 | 791 | 9512 | exclusion | phecode |
| 440.1 | Atherosclerosis of renal artery | Circulatory System | 0.988 | 0.782 – 1.25 | 0.919 | 78 | 1095 | exclusion | phecode |
| 440.2 | Atherosclerosis of the extremities | Circulatory System | 0.978 | 0.888 – 1.08 | 0.651 | 445 | 6411 | exclusion | phecode |
| 440.21 |
Atherosclerosis of native arteries of theAtherosclerosis of native arteries of the extremities with ulceration or gangrene
|
Circulatory System | 0.982 | 0.783 – 1.23 | 0.874 | 81 | 1232 | exclusion | phecode |
| 440.22 |
Atherosclerosis of native arteries of theAtherosclerosis of native arteries of the extremities with intermittent claudication
|
Circulatory System | 0.968 | 0.86 – 1.09 | 0.594 | 293 | 4572 | exclusion | phecode |
| 440.9 | Atherosclerosis of aorta | Circulatory System | 1.09 | 0.955 – 1.24 | 0.203 | 241 | 3726 | exclusion | phecode |
| 441 | Vascular insufficiency of intestine | Circulatory System | 0.971 | 0.837 – 1.13 | 0.694 | 191 | 2571 | exclusion | phecode |
| 441.1 | Acute vascular insufficiency of intestine | Circulatory System | 0.925 | 0.745 – 1.15 | 0.481 | 95 | 1201 | exclusion | phecode |
| 441.2 | Chronic vascular insufficiency of intestine | Circulatory System | 0.97 | 0.729 – 1.29 | 0.834 | 42 | 752 | exclusion | phecode |
| 442 | Other aneurysm | Circulatory System | 0.978 | 0.914 – 1.05 | 0.524 | 913 | 10344 | exclusion | phecode |
| 442.1 | Aortic aneurysm | Circulatory System | 0.963 | 0.888 – 1.04 | 0.361 | 655 | 7655 | exclusion | phecode |
| 442.11 | Abdominal aortic aneurysm | Circulatory System | 1.03 | 0.91 – 1.16 | 0.679 | 282 | 4668 | exclusion | phecode |
| 442.2 | Aneurysm of iliac artery | Circulatory System | 1.06 | 0.788 – 1.42 | 0.706 | 49 | 834 | exclusion | phecode |
| 442.3 | Aneurysm of artery of lower extremity | Circulatory System | 0.775 | 0.574 – 1.05 | 0.0973 | 43 | 800 | exclusion | phecode |
| 442.4 | Arterial dissection | Circulatory System | 0.906 | 0.695 – 1.18 | 0.465 | 62 | 877 | exclusion | phecode |
| 442.8 | Aneurysm of other specified artery | Circulatory System | 0.949 | 0.808 – 1.11 | 0.523 | 162 | 1934 | exclusion | phecode |
| 443 | Peripheral vascular disease | Circulatory System | 0.949 | 0.892 – 1.01 | 0.101 | 1097 | 12309 | exclusion | phecode |
| 443.1 | Raynaud's syndrome | Circulatory System | 0.944 | 0.852 – 1.05 | 0.274 | 410 | 3870 | exclusion | phecode |
| 443.7 |
Peripheral angiopathy in diseases classifiedPeripheral angiopathy in diseases classified elsewhere
|
Circulatory System | 1.03 | 0.828 – 1.28 | 0.786 | 86 | 1035 | exclusion | phecode |
| 443.8 | Other specified peripheral vascular diseases | Circulatory System | 0.942 | 0.878 – 1.01 | 0.0954 | 859 | 10818 | exclusion | phecode |
| 443.9 | Peripheral vascular disease, unspecified | Circulatory System | 0.986 | 0.911 – 1.07 | 0.729 | 665 | 9029 | exclusion | phecode |
| 444 | Arterial embolism and thrombosis | Circulatory System | 0.98 | 0.865 – 1.11 | 0.756 | 262 | 4087 | exclusion | phecode |
| 444.1 |
Arterial embolism and thrombosis of lowerArterial embolism and thrombosis of lower extremity artery
|
Circulatory System | 0.828 | 0.66 – 1.04 | 0.102 | 74 | 1467 | exclusion | phecode |
| 444.2 | Embolism and thrombosis of abdominal aorta | Circulatory System | 1.36 | 0.896 – 2.07 | 0.148 | 22 | 705 | exclusion | phecode |
| 446 | Polyarteritis nodosa and allied conditions | Circulatory System | 0.97 | 0.837 – 1.12 | 0.683 | 207 | 2294 | exclusion | phecode |
| 446.4 | Wegener's granulomatosis | Circulatory System | 0.86 | 0.65 – 1.14 | 0.287 | 56 | 581 | exclusion | phecode |
| 446.5 | Giant cell arteritis | Circulatory System | 0.887 | 0.602 – 1.31 | 0.547 | 34 | 360 | exclusion | phecode |
| 446.9 | Arteritis NOS | Circulatory System | 0.931 | 0.768 – 1.13 | 0.465 | 122 | 1493 | exclusion | phecode |
| 447 | Other disorders of arteries and arterioles | Circulatory System | 0.963 | 0.902 – 1.03 | 0.248 | 1025 | 11178 | exclusion | phecode |
| 447.1 | Stricture of artery | Circulatory System | 0.887 | 0.744 – 1.06 | 0.182 | 136 | 2516 | exclusion | phecode |
| 447.7 | Aortic ectasia | Circulatory System | 0.995 | 0.893 – 1.11 | 0.924 | 368 | 3648 | exclusion | phecode |
| 448 | Disease of capillaries | Circulatory System | 0.992 | 0.917 – 1.07 | 0.834 | 711 | 6251 | exclusion | phecode |
| 450 | Noninfectious disorders of lymphatic channels | Circulatory System | 0.991 | 0.93 – 1.06 | 0.771 | 1086 | 10278 | exclusion | phecode |
| 451 | Phlebitis and thrombophlebitis | Circulatory System | 1.05 | 0.944 – 1.18 | 0.352 | 354 | 3528 | exclusion | phecode |
| 451.2 |
Phlebitis and thrombophlebitis of lowerPhlebitis and thrombophlebitis of lower extremities
|
Circulatory System | 0.94 | 0.779 – 1.14 | 0.521 | 124 | 1188 | exclusion | phecode |
| 452 | Other venous embolism and thrombosis | Circulatory System | 0.983 | 0.94 – 1.03 | 0.471 | 2225 | 14941 | exclusion | phecode |
| 452.1 | Iatrogenic pulmonary embolism and infarction | Circulatory System | 1.11 | 0.924 – 1.33 | 0.27 | 132 | 1357 | exclusion | phecode |
| 452.2 | Deep vein thrombosis [DVT] | Circulatory System | 0.964 | 0.913 – 1.02 | 0.18 | 1492 | 13225 | exclusion | phecode |
| 452.8 | Postphlebitic syndrome | Circulatory System | 1.02 | 0.813 – 1.29 | 0.84 | 81 | 793 | exclusion | phecode |
| 453 | Chronic venous hypertension | Circulatory System | 0.982 | 0.815 – 1.18 | 0.846 | 115 | 1092 | exclusion | phecode |
| 454 | Varicose veins | Circulatory System | 1.03 | 0.975 – 1.09 | 0.286 | 1475 | 12138 | exclusion | phecode |
| 454.1 | Varicose veins of lower extremity | Circulatory System | 1.02 | 0.962 – 1.08 | 0.496 | 1262 | 10467 | exclusion | phecode |
| 454.11 | Varicose veins of lower extremity, symptomtic | Circulatory System | 0.991 | 0.923 – 1.07 | 0.812 | 831 | 7397 | exclusion | phecode |
| 455 | Hemorrhoids | Circulatory System | 0.983 | 0.944 – 1.02 | 0.399 | 3020 | 14918 | exclusion | phecode |
| 456 | Chronic venous insufficiency [CVI] | Circulatory System | 1.03 | 0.973 – 1.08 | 0.332 | 1574 | 12178 | exclusion | phecode |
| 457 |
Encounter for long-term (current) use ofEncounter for long-term (current) use of anticoagulants, antithrombotics, aspirin
|
Circulatory System | 0.979 | 0.909 – 1.06 | 0.585 | 782 | 7018 | exclusion | phecode |
| 457.2 |
Encounter for long-term (current) use ofEncounter for long-term (current) use of antiplatelets/antithrombotics
|
Circulatory System | 0.981 | 0.807 – 1.19 | 0.845 | 103 | 1379 | exclusion | phecode |
| 457.3 | Encounter for long-term (current) use of aspirin | Circulatory System | 0.978 | 0.906 – 1.06 | 0.565 | 735 | 6710 | exclusion | phecode |
| 458 | Hypotension | Circulatory System | 0.996 | 0.952 – 1.04 | 0.876 | 2194 | 16368 | exclusion | phecode |
| 458.1 | Orthostatic hypotension | Circulatory System | 0.936 | 0.862 – 1.02 | 0.121 | 627 | 6313 | exclusion | phecode |
| 458.2 | Iatrogenic hypotension | Circulatory System | 1.1 | 0.996 – 1.22 | 0.0589 | 425 | 5110 | exclusion | phecode |
| 458.9 | Hypotension NOS | Circulatory System | 1 | 0.956 – 1.05 | 0.916 | 1966 | 15765 | exclusion | phecode |
| 459 | Other disorders of circulatory system | Circulatory System | 0.975 | 0.939 – 1.01 | 0.186 | 3393 | 18071 | exclusion | phecode |
| 459.1 | Hemorrhage NOS | Circulatory System | 0.988 | 0.894 – 1.09 | 0.819 | 431 | 4126 | exclusion | phecode |
| 459.7 | Blood vessel replaced | Circulatory System | 0.998 | 0.909 – 1.1 | 0.965 | 489 | 6250 | exclusion | phecode |
| 459.9 | Circulatory disease NEC | Circulatory System | 0.975 | 0.936 – 1.02 | 0.23 | 2862 | 17220 | exclusion | phecode |
| 464 | Acute sinusitis | Respiratory | 0.986 | 0.945 – 1.03 | 0.496 | 2679 | 16047 | exclusion | phecode |
| 465 |
Acute upper respiratory infections of multipleAcute upper respiratory infections of multiple or unspecified sites
|
Respiratory | 0.998 | 0.967 – 1.03 | 0.911 | 5330 | 17716 | exclusion | phecode |
| 465.2 | Acute pharyngitis | Respiratory | 0.997 | 0.958 – 1.04 | 0.889 | 3082 | 16396 | exclusion | phecode |
| 465.4 | Acute laryngitis and tracheitis | Respiratory | 1.07 | 0.929 – 1.22 | 0.365 | 235 | 2262 | exclusion | phecode |
| 470 | Septal Deviations/Turbinate Hypertrophy | Respiratory | 0.964 | 0.901 – 1.03 | 0.288 | 987 | 8956 | exclusion | phecode |
| 471 | Nasal polyps | Respiratory | 1 | 0.897 – 1.12 | 0.942 | 340 | 2838 | exclusion | phecode |
| 472 | Chronic pharyngitis and nasopharyngitis | Respiratory | 0.991 | 0.926 – 1.06 | 0.792 | 965 | 8546 | exclusion | phecode |
| 473 | Diseases of the larynx and vocal cords | Respiratory | 1.04 | 0.987 – 1.11 | 0.132 | 1389 | 12181 | exclusion | phecode |
| 473.1 | Chronic laryngitis | Respiratory | 0.719 | 0.472 – 1.09 | 0.124 | 24 | 337 | exclusion | phecode |
| 473.3 | Paralysis/spasm of vocal cords or larynx | Respiratory | 1 | 0.892 – 1.13 | 0.945 | 313 | 3031 | exclusion | phecode |
| 473.4 | Voice disturbance | Respiratory | 1.06 | 0.995 – 1.13 | 0.0686 | 1064 | 10484 | exclusion | phecode |
| 474 | Acute and chronic tonsillitis | Respiratory | 1.05 | 0.959 – 1.15 | 0.287 | 555 | 4528 | exclusion | phecode |
| 474.1 | Acute tonsillitis | Respiratory | 0.977 | 0.85 – 1.12 | 0.743 | 237 | 1958 | exclusion | phecode |
| 474.2 | Chronic tonsillitis and adenoiditis | Respiratory | 1.06 | 0.963 – 1.18 | 0.223 | 448 | 3729 | exclusion | phecode |
| 475 | Chronic sinusitis | Respiratory | 0.995 | 0.952 – 1.04 | 0.825 | 2379 | 13821 | exclusion | phecode |
| 475.9 | Postnasal drip | Respiratory | 1.01 | 0.923 – 1.11 | 0.812 | 528 | 4431 | exclusion | phecode |
| 476 | Allergic rhinitis | Respiratory | 0.996 | 0.967 – 1.03 | 0.766 | 6972 | 13936 | exclusion | phecode |
| 477 | Epistaxis or throat hemorrhage | Respiratory | 0.916 | 0.84 – 1 | 0.049 | 583 | 5527 | exclusion | phecode |
| 478 | Throat pain | Respiratory | 1.14 | 0.977 – 1.32 | 0.0959 | 195 | 2140 | exclusion | phecode |
| 479 | Other upper respiratory disease | Respiratory | 0.974 | 0.935 – 1.02 | 0.22 | 2792 | 13895 | exclusion | phecode |
| 480 | Pneumonia | Respiratory | 1.01 | 0.971 – 1.06 | 0.548 | 2524 | 18949 | exclusion | phecode |
| 480.1 | Bacterial pneumonia | Respiratory | 1 | 0.91 – 1.1 | 0.961 | 460 | 5522 | exclusion | phecode |
| 480.11 | Pneumococcal pneumonia | Respiratory | 1.03 | 0.896 – 1.18 | 0.7 | 236 | 2736 | exclusion | phecode |
| 480.12 | Pseudomonal pneumonia | Respiratory | 0.821 | 0.626 – 1.08 | 0.153 | 56 | 723 | exclusion | phecode |
| 480.13 | MRSA pneumonia | Respiratory | 1.01 | 0.75 – 1.37 | 0.925 | 43 | 592 | exclusion | phecode |
| 480.2 | Viral pneumonia | Respiratory | 0.964 | 0.775 – 1.2 | 0.74 | 94 | 949 | exclusion | phecode |
| 480.3 | Pneumonia due to fungus (mycoses) | Respiratory | 0.801 | 0.609 – 1.05 | 0.113 | 49 | 796 | exclusion | phecode |
| 480.5 | Bronchopneumonia and lung abscess | Respiratory | 1.09 | 0.787 – 1.5 | 0.614 | 41 | 618 | exclusion | phecode |
| 481 | Influenza | Respiratory | 0.996 | 0.922 – 1.08 | 0.921 | 738 | 6978 | exclusion | phecode |
| 483 | Acute bronchitis and bronchiolitis | Respiratory | 1.02 | 0.966 – 1.07 | 0.518 | 1719 | 15381 | exclusion | phecode |
| 495 | Asthma | Respiratory | 1.02 | 0.982 – 1.05 | 0.374 | 4526 | 18142 | exclusion | phecode |
| 495.1 | Chronic obstructive asthma | Respiratory | 1.07 | 0.889 – 1.29 | 0.473 | 114 | 2114 | exclusion | phecode |
| 495.11 | Chronic obstructive asthma with exacerbation | Respiratory | 1.03 | 0.7 – 1.51 | 0.886 | 22 | 420 | exclusion | phecode |
| 495.2 | Asthma with exacerbation | Respiratory | 1.04 | 0.974 – 1.12 | 0.229 | 954 | 9178 | exclusion | phecode |
| 496 | Chronic airway obstruction | Respiratory | 0.941 | 0.881 – 1 | 0.0669 | 975 | 14687 | exclusion | phecode |
| 496.1 | Emphysema | Respiratory | 0.96 | 0.813 – 1.13 | 0.626 | 139 | 9683 | exclusion | phecode |
| 496.2 | Chronic bronchitis | Respiratory | 0.924 | 0.855 – 0.998 | 0.0452 | 686 | 13709 | exclusion | phecode |
| 496.21 | Obstructive chronic bronchitis | Respiratory | 0.897 | 0.822 – 0.979 | 0.0153 | 529 | 13031 | exclusion | phecode |
| 496.3 | Bronchiectasis | Respiratory | 0.891 | 0.782 – 1.01 | 0.0814 | 239 | 2866 | exclusion | phecode |
| 497 | Bronchitis | Respiratory | 1 | 0.938 – 1.07 | 0.927 | 966 | 10270 | exclusion | phecode |
| 498 | Acute bronchospasm | Respiratory | 1.02 | 0.898 – 1.17 | 0.731 | 251 | 2763 | exclusion | phecode |
| 499 | Cystic fibrosis | Respiratory | 0.996 | 0.813 – 1.22 | 0.968 | 102 | 855 | exclusion | phecode |
| 500 | Lung disease due to external agents | Respiratory | 0.863 | 0.75 – 0.992 | 0.0387 | 223 | 2546 | exclusion | phecode |
| 500.1 | Extrinsic allergic alveolitis | Respiratory | 0.845 | 0.62 – 1.15 | 0.286 | 44 | 458 | exclusion | phecode |
| 500.2 | Pneumoconiosis | Respiratory | 1.3 | 0.82 – 2.07 | 0.264 | 23 | 291 | exclusion | phecode |
| 501 | Pneumonitis due to inhalation of food or vomitus | Respiratory | 0.947 | 0.826 – 1.09 | 0.437 | 215 | 2965 | exclusion | phecode |
| 502 | Postinflammatory pulmonary fibrosis | Respiratory | 0.955 | 0.85 – 1.07 | 0.436 | 321 | 3859 | exclusion | phecode |
| 503 | Pulmonary congestion and hypostasis | Respiratory | 1.02 | 0.906 – 1.14 | 0.774 | 313 | 3994 | exclusion | phecode |
| 504 | Other alveolar and parietoalveolar pneumonopathy | Respiratory | 0.959 | 0.836 – 1.1 | 0.555 | 223 | 2815 | exclusion | phecode |
| 504.1 | Idiopathic fibrosing alveolitis | Respiratory | 0.916 | 0.752 – 1.12 | 0.382 | 109 | 1442 | exclusion | phecode |
| 505 | Other pulmonary inflamation or edema | Respiratory | 1.03 | 0.949 – 1.11 | 0.499 | 659 | 7503 | exclusion | phecode |
| 506 | Empyema and pneumothorax | Respiratory | 0.989 | 0.931 – 1.05 | 0.736 | 1155 | 12430 | exclusion | phecode |
| 507 | Pleurisy; pleural effusion | Respiratory | 1.06 | 0.998 – 1.12 | 0.0585 | 1219 | 12972 | exclusion | phecode |
| 508 |
Pulmonary collapse; interstitial andPulmonary collapse; interstitial and compensatory emphysema
|
Respiratory | 1.05 | 0.979 – 1.12 | 0.186 | 1015 | 11028 | exclusion | phecode |
| 509 | Respiratory failure, insufficiency, arrest | Respiratory | 0.984 | 0.933 – 1.04 | 0.562 | 1549 | 14765 | exclusion | phecode |
| 509.1 | Respiratory failure | Respiratory | 0.971 | 0.9 – 1.05 | 0.461 | 724 | 9178 | exclusion | phecode |
| 509.2 | Respiratory insufficiency | Respiratory | 0.946 | 0.857 – 1.04 | 0.271 | 439 | 5633 | exclusion | phecode |
| 509.3 |
Pulmonary insufficiency or respiratory failurePulmonary insufficiency or respiratory failure following trauma and surgery
|
Respiratory | 1.06 | 0.974 – 1.15 | 0.183 | 634 | 7787 | exclusion | phecode |
| 509.8 |
Dependence on respirator [Ventilator] orDependence on respirator [Ventilator] or supplemental oxygen
|
Respiratory | 0.942 | 0.866 – 1.02 | 0.163 | 617 | 8257 | exclusion | phecode |
| 510 | Other diseases of lung | Respiratory | 0.956 | 0.914 – 0.999 | 0.0464 | 2280 | 17962 | exclusion | phecode |
| 510.2 | Lung transplant | Respiratory | 1.11 | 0.873 – 1.4 | 0.407 | 77 | 882 | exclusion | phecode |
| 512 | Other symptoms of respiratory system | Respiratory | 1 | 0.976 – 1.03 | 0.861 | 8881 | 14859 | exclusion | phecode |
| 512.1 | Wheezing | Respiratory | 0.935 | 0.859 – 1.02 | 0.124 | 589 | 6956 | exclusion | phecode |
| 512.2 | Painful respiration | Respiratory | 0.991 | 0.931 – 1.05 | 0.773 | 1121 | 11023 | exclusion | phecode |
| 512.3 | Abnormal chest sounds | Respiratory | 0.83 | 0.684 – 1.01 | 0.0593 | 109 | 1361 | exclusion | phecode |
| 512.7 | Shortness of breath | Respiratory | 1.02 | 0.989 – 1.06 | 0.19 | 4385 | 14804 | exclusion | phecode |
| 512.8 | Cough | Respiratory | 1 | 0.967 – 1.03 | 0.99 | 4794 | 14858 | exclusion | phecode |
| 512.9 | Other dyspnea | Respiratory | 1.01 | 0.98 – 1.05 | 0.429 | 4943 | 14824 | exclusion | phecode |
| 513 | Respiratory abnormalities | Respiratory | 1.02 | 0.99 – 1.05 | 0.192 | 5803 | 17920 | exclusion | phecode |
| 513.3 | Hypoventilation | Respiratory | 1.04 | 0.937 – 1.15 | 0.464 | 375 | 4318 | exclusion | phecode |
| 513.31 | Apnea | Respiratory | 1.04 | 0.899 – 1.19 | 0.631 | 205 | 2331 | exclusion | phecode |
| 513.32 | Orthopnea | Respiratory | 1.08 | 0.864 – 1.34 | 0.511 | 83 | 1017 | exclusion | phecode |
| 513.4 | Hyperventilation | Respiratory | 1 | 0.871 – 1.16 | 0.963 | 199 | 2507 | exclusion | phecode |
| 513.8 | Disorders of diaphragm | Respiratory | 0.967 | 0.804 – 1.16 | 0.721 | 124 | 1201 | exclusion | phecode |
| 514 | Abnormal findings examination of lungs | Respiratory | 0.986 | 0.941 – 1.03 | 0.544 | 2071 | 17395 | exclusion | phecode |
| 514.1 |
Abnormal results of function study of pulmonaryAbnormal results of function study of pulmonary system
|
Respiratory | 0.864 | 0.706 – 1.06 | 0.155 | 110 | 1267 | exclusion | phecode |
| 514.2 | Solitary pulmonary nodule | Respiratory | 1.01 | 0.951 – 1.08 | 0.724 | 1129 | 13297 | exclusion | phecode |
| 516 | Abnormal sputum | Respiratory | 0.993 | 0.88 – 1.12 | 0.914 | 281 | 3548 | exclusion | phecode |
| 516.1 | Hemoptysis | Respiratory | 1.01 | 0.88 – 1.15 | 0.936 | 234 | 2940 | exclusion | phecode |
| 519 |
Other diseases of respiratory system, notOther diseases of respiratory system, not elsewhere classified
|
Respiratory | 0.982 | 0.943 – 1.02 | 0.384 | 2746 | 20144 | exclusion | phecode |
| 519.1 | Tracheostomy complications | Respiratory | 1.01 | 0.787 – 1.29 | 0.964 | 67 | 1067 | exclusion | phecode |
| 519.2 | Respiratory complications | Respiratory | 1.07 | 0.918 – 1.26 | 0.373 | 170 | 2126 | exclusion | phecode |
| 519.8 | Other diseases of respiratory system, NEC | Respiratory | 0.975 | 0.902 – 1.05 | 0.527 | 693 | 7959 | exclusion | phecode |
| 519.9 |
Symptoms involving respiratory system and otherSymptoms involving respiratory system and other chest symptoms
|
Respiratory | 0.987 | 0.941 – 1.04 | 0.591 | 1942 | 17281 | exclusion | phecode |
| 520 | Disorders of tooth development | Digestive | 0.964 | 0.813 – 1.14 | 0.669 | 148 | 2048 | exclusion | phecode |
| 520.1 | Hereditary disturbances in tooth structure | Digestive | 1.11 | 0.833 – 1.49 | 0.465 | 45 | 821 | exclusion | phecode |
| 520.2 | Disturbances in tooth eruption | Digestive | 0.969 | 0.797 – 1.18 | 0.751 | 111 | 1278 | exclusion | phecode |
| 521 | Diseases of hard tissues of teeth | Digestive | 0.977 | 0.865 – 1.1 | 0.7 | 278 | 4521 | exclusion | phecode |
| 521.1 | Dental caries | Digestive | 0.995 | 0.877 – 1.13 | 0.938 | 256 | 4199 | exclusion | phecode |
| 521.2 | Dental abrasion, erosion and attrition | Digestive | 0.951 | 0.609 – 1.49 | 0.827 | 16 | 274 | exclusion | phecode |
| 522 | Diseases of pulp and periapical tissues | Digestive | 1.06 | 0.912 – 1.24 | 0.442 | 181 | 2764 | exclusion | phecode |
| 522.5 | Periapical abscess | Digestive | 1.03 | 0.874 – 1.22 | 0.697 | 147 | 2362 | exclusion | phecode |
| 523 | Gingival and periodontal diseases | Digestive | 0.911 | 0.802 – 1.03 | 0.152 | 261 | 3542 | exclusion | phecode |
| 523.1 | Gingivitis | Digestive | 0.797 | 0.603 – 1.05 | 0.11 | 57 | 733 | exclusion | phecode |
| 523.3 | Periodontitis (acute or chronic) | Digestive | 0.961 | 0.798 – 1.16 | 0.674 | 115 | 1800 | exclusion | phecode |
| 523.31 | Acute periodontitis | Digestive | 0.994 | 0.813 – 1.21 | 0.951 | 96 | 1531 | exclusion | phecode |
| 523.32 | Chronic periodontitis | Digestive | 0.695 | 0.497 – 0.971 | 0.0331 | 35 | 595 | exclusion | phecode |
| 524 | Dentofacial anomalies, including malocclusion | Digestive | 1.06 | 0.919 – 1.22 | 0.431 | 225 | 2129 | exclusion | phecode |
| 524.3 | Anomalies of tooth position/malocclusion | Digestive | 1.04 | 0.878 – 1.23 | 0.668 | 154 | 1364 | exclusion | phecode |
| 525 |
Other diseases of the teeth and supportingOther diseases of the teeth and supporting structures
|
Digestive | 1.09 | 0.983 – 1.22 | 0.101 | 375 | 5293 | exclusion | phecode |
| 525.1 | Loss of teeth or edentulism | Digestive | 1.13 | 0.956 – 1.33 | 0.153 | 151 | 1860 | exclusion | phecode |
| 526 | Diseases of the jaws | Digestive | 1.02 | 0.965 – 1.08 | 0.466 | 1360 | 14082 | exclusion | phecode |
| 526.1 | Cysts of the jaws | Digestive | 1.17 | 0.945 – 1.46 | 0.147 | 93 | 1247 | exclusion | phecode |
| 526.3 | Anomalies of jaw size/symmetry | Digestive | 1.16 | 0.988 – 1.37 | 0.0698 | 168 | 1461 | exclusion | phecode |
| 526.4 | Temporomandibular joint disorders | Digestive | 0.97 | 0.902 – 1.04 | 0.413 | 831 | 8151 | exclusion | phecode |
| 526.41 | Temporomandibular joint disorder, unspecified | Digestive | 0.977 | 0.9 – 1.06 | 0.577 | 656 | 6422 | exclusion | phecode |
| 526.42 | Arthralgia/ankylosis of temporomandibular joint | Digestive | 0.942 | 0.85 – 1.04 | 0.253 | 423 | 4088 | exclusion | phecode |
| 526.5 | Inflammatory conditions of jaw | Digestive | 1.01 | 0.828 – 1.23 | 0.911 | 96 | 1420 | exclusion | phecode |
| 526.8 | Exostosis of jaw | Digestive | 1 | 0.671 – 1.5 | 0.981 | 22 | 258 | exclusion | phecode |
| 526.9 | Jaw disease NOS | Digestive | 1.01 | 0.873 – 1.17 | 0.905 | 207 | 2483 | exclusion | phecode |
| 527 | Diseases of the salivary glands | Digestive | 0.956 | 0.889 – 1.03 | 0.225 | 788 | 8715 | exclusion | phecode |
| 527.1 | Hypertrophy of salivary gland | Digestive | 0.754 | 0.516 – 1.1 | 0.145 | 30 | 285 | exclusion | phecode |
| 527.2 | Sialoadenitis | Digestive | 1.04 | 0.892 – 1.21 | 0.63 | 176 | 1992 | exclusion | phecode |
| 527.7 | Disturbance of salivary secretion | Digestive | 0.926 | 0.838 – 1.02 | 0.127 | 414 | 4571 | exclusion | phecode |
| 527.8 | Other specified diseases of the salivary glands | Digestive | 0.978 | 0.806 – 1.19 | 0.818 | 114 | 1227 | exclusion | phecode |
| 528 |
Diseases of the oral soft tissues, excludingDiseases of the oral soft tissues, excluding lesions specific for gingiva and tongue
|
Digestive | 0.989 | 0.932 – 1.05 | 0.713 | 1251 | 13232 | exclusion | phecode |
| 528.1 | Stomatitis and mucositis | Digestive | 0.997 | 0.89 – 1.12 | 0.952 | 345 | 3450 | exclusion | phecode |
| 528.11 | Stomatitis and mucositis (ulcerative) | Digestive | 0.981 | 0.794 – 1.21 | 0.862 | 99 | 1085 | exclusion | phecode |
| 528.12 | Oral aphthae | Digestive | 1.07 | 0.884 – 1.29 | 0.503 | 127 | 1168 | exclusion | phecode |
| 528.3 | Cellulitis and abscess of oral soft tissues | Digestive | 0.948 | 0.763 – 1.18 | 0.626 | 89 | 1187 | exclusion | phecode |
| 528.4 | Cysts of oral soft tissues | Digestive | 0.982 | 0.755 – 1.28 | 0.891 | 62 | 644 | exclusion | phecode |
| 528.41 | Cyst of the salivary gland | Digestive | 0.964 | 0.706 – 1.32 | 0.818 | 43 | 399 | exclusion | phecode |
| 528.5 | Diseases of lips | Digestive | 0.995 | 0.87 – 1.14 | 0.941 | 242 | 2319 | exclusion | phecode |
| 528.6 | Leukoplakia of oral mucosa | Digestive | 0.953 | 0.712 – 1.28 | 0.746 | 48 | 671 | exclusion | phecode |
| 528.7 | Sialolithiasis | Digestive | 1.09 | 0.854 – 1.38 | 0.502 | 71 | 868 | exclusion | phecode |
| 529 | Diseases and other conditions of the tongue | Digestive | 0.958 | 0.855 – 1.07 | 0.465 | 315 | 3454 | exclusion | phecode |
| 529.1 | Glossitis | Digestive | 0.996 | 0.766 – 1.29 | 0.974 | 63 | 616 | exclusion | phecode |
| 529.6 | Glossodynia | Digestive | 0.94 | 0.754 – 1.17 | 0.582 | 81 | 864 | exclusion | phecode |
| 530 | Diseases of esophagus | Digestive | 1.01 | 0.981 – 1.04 | 0.54 | 7836 | 15178 | exclusion | phecode |
| 530.1 | Esophagitis, GERD and related diseases | Digestive | 1.01 | 0.982 – 1.04 | 0.49 | 7610 | 15178 | exclusion | phecode |
| 530.11 | GERD | Digestive | 1.01 | 0.978 – 1.04 | 0.629 | 7423 | 15177 | exclusion | phecode |
| 530.12 | Ulcer of esophagus | Digestive | 0.952 | 0.819 – 1.11 | 0.524 | 181 | 2039 | exclusion | phecode |
| 530.13 | Barrett's esophagus | Digestive | 0.991 | 0.874 – 1.12 | 0.885 | 254 | 3505 | exclusion | phecode |
| 530.14 | Reflux esophagitis | Digestive | 0.997 | 0.932 – 1.07 | 0.941 | 930 | 9099 | exclusion | phecode |
| 530.15 | Eosinophilic esophagitis | Digestive | 1.04 | 0.883 – 1.23 | 0.628 | 159 | 1253 | exclusion | phecode |
| 530.2 | Esophageal bleeding (varices/hemorrhage) | Digestive | 1.03 | 0.907 – 1.16 | 0.677 | 272 | 3198 | exclusion | phecode |
| 530.3 | Stricture and stenosis of esophagus | Digestive | 0.969 | 0.878 – 1.07 | 0.522 | 438 | 4522 | exclusion | phecode |
| 530.5 | Disorders of esophageal motility | Digestive | 0.973 | 0.858 – 1.1 | 0.669 | 268 | 2799 | exclusion | phecode |
| 530.6 | Diverticulum of esophagus, acquired | Digestive | 0.924 | 0.709 – 1.2 | 0.557 | 62 | 573 | exclusion | phecode |
| 530.7 | Gastroesophageal laceration-hemorrhage syndrome | Digestive | 0.906 | 0.657 – 1.25 | 0.548 | 39 | 417 | exclusion | phecode |
| 530.9 | Heartburn | Digestive | 1.04 | 0.963 – 1.12 | 0.322 | 741 | 7969 | exclusion | phecode |
| 531 | Peptic ulcer (excl. esophageal) | Digestive | 0.972 | 0.908 – 1.04 | 0.424 | 896 | 9984 | exclusion | phecode |
| 531.1 | Hemorrhage from gastrointestinal ulcer | Digestive | 0.898 | 0.763 – 1.06 | 0.191 | 159 | 1742 | exclusion | phecode |
| 531.2 | Gastric ulcer | Digestive | 0.979 | 0.894 – 1.07 | 0.637 | 520 | 5847 | exclusion | phecode |
| 531.3 | Duodenal ulcer | Digestive | 0.93 | 0.802 – 1.08 | 0.341 | 189 | 2105 | exclusion | phecode |
| 531.4 | Peptic ulcer, site unspecified | Digestive | 0.905 | 0.81 – 1.01 | 0.0757 | 336 | 3908 | exclusion | phecode |
| 531.5 | Gastrojejunal ulcer | Digestive | 1.07 | 0.852 – 1.34 | 0.563 | 76 | 723 | exclusion | phecode |
| 532 | Dysphagia | Digestive | 1.01 | 0.965 – 1.05 | 0.704 | 2456 | 14360 | exclusion | phecode |
| 535 | Gastritis and duodenitis | Digestive | 0.993 | 0.937 – 1.05 | 0.803 | 1290 | 13750 | exclusion | phecode |
| 535.1 | Acute gastritis | Digestive | 0.981 | 0.898 – 1.07 | 0.678 | 529 | 5877 | exclusion | phecode |
| 535.2 | Atrophic gastritis | Digestive | 0.991 | 0.85 – 1.16 | 0.912 | 172 | 1711 | exclusion | phecode |
| 535.6 | Duodenitis | Digestive | 0.882 | 0.736 – 1.06 | 0.173 | 134 | 1604 | exclusion | phecode |
| 535.8 | Other specified gastritis | Digestive | 1.08 | 0.961 – 1.21 | 0.202 | 322 | 3189 | exclusion | phecode |
| 535.9 | Gastritis and duodenitis, NOS | Digestive | 1.02 | 0.935 – 1.11 | 0.675 | 583 | 6381 | exclusion | phecode |
| 536 | Disorders of function of stomach | Digestive | 0.957 | 0.905 – 1.01 | 0.121 | 1411 | 14123 | exclusion | phecode |
| 536.3 | Gastroparesis | Digestive | 1.02 | 0.913 – 1.14 | 0.747 | 348 | 3664 | exclusion | phecode |
| 536.7 |
Complications of gastrostomy, colostomy andComplications of gastrostomy, colostomy and enterostomy
|
Digestive | 0.933 | 0.793 – 1.1 | 0.408 | 153 | 2055 | exclusion | phecode |
| 536.8 |
Dyspepsia and other specified disorders ofDyspepsia and other specified disorders of function of stomach
|
Digestive | 0.964 | 0.905 – 1.03 | 0.256 | 1083 | 10853 | exclusion | phecode |
| 537 | Other disorders of stomach and duodenum | Digestive | 0.997 | 0.944 – 1.05 | 0.899 | 1503 | 15023 | exclusion | phecode |
| 537.1 | Lesions of stomach and duodenum | Digestive | 0.802 | 0.631 – 1.02 | 0.0717 | 73 | 823 | exclusion | phecode |
| 539 | Bariatric surgery | Digestive | 0.998 | 0.927 – 1.07 | 0.951 | 830 | 7736 | exclusion | phecode |
| 540 | Appendiceal conditions | Digestive | 1.05 | 0.928 – 1.19 | 0.432 | 277 | 2586 | exclusion | phecode |
| 540.1 | Appendicitis | Digestive | 1.02 | 0.894 – 1.17 | 0.728 | 239 | 2217 | exclusion | phecode |
| 540.11 | Acute appendicitis | Digestive | 1.08 | 0.93 – 1.26 | 0.313 | 200 | 1841 | exclusion | phecode |
| 550 | Abdominal hernia | Digestive | 0.993 | 0.956 – 1.03 | 0.739 | 3144 | 18870 | exclusion | phecode |
| 550.1 | Inguinal hernia | Digestive | 1 | 0.932 – 1.08 | 0.96 | 844 | 7323 | exclusion | phecode |
| 550.2 | Diaphragmatic hernia | Digestive | 0.992 | 0.937 – 1.05 | 0.787 | 1327 | 12524 | exclusion | phecode |
| 550.3 | Femoral hernia | Digestive | 1.15 | 0.869 – 1.52 | 0.33 | 66 | 646 | exclusion | phecode |
| 550.4 | Umbilical hernia | Digestive | 0.955 | 0.879 – 1.04 | 0.272 | 629 | 6206 | exclusion | phecode |
| 550.5 | Ventral hernia | Digestive | 0.978 | 0.914 – 1.05 | 0.509 | 942 | 10551 | exclusion | phecode |
| 550.6 | Incisional hernia | Digestive | 1.02 | 0.936 – 1.11 | 0.635 | 564 | 6249 | exclusion | phecode |
| 555 |
Inflammatory bowel disease and otherInflammatory bowel disease and other gastroenteritis and colitis
|
Digestive | 0.969 | 0.897 – 1.05 | 0.421 | 743 | 7898 | exclusion | phecode |
| 555.1 | Regional enteritis | Digestive | 0.946 | 0.856 – 1.04 | 0.272 | 439 | 4780 | exclusion | phecode |
| 555.2 | Ulcerative colitis | Digestive | 0.975 | 0.884 – 1.07 | 0.605 | 467 | 4862 | exclusion | phecode |
| 555.21 | Ulcerative colitis (chronic) | Digestive | 0.947 | 0.839 – 1.07 | 0.383 | 291 | 2818 | exclusion | phecode |
| 556 | Ulceration of the lower GI tract | Digestive | 1.08 | 0.955 – 1.23 | 0.213 | 264 | 3007 | exclusion | phecode |
| 556.1 | Ulceration of intestine | Digestive | 1.08 | 0.942 – 1.24 | 0.272 | 225 | 2608 | exclusion | phecode |
| 556.11 |
Angiodysplasia of intestine (without mention ofAngiodysplasia of intestine (without mention of hemorrhage)
|
Digestive | 1.08 | 0.847 – 1.36 | 0.552 | 72 | 965 | exclusion | phecode |
| 557 | Intestinal malabsorption (non-celiac) | Digestive | 1 | 0.937 – 1.07 | 0.953 | 972 | 9060 | exclusion | phecode |
| 557.1 | Celiac disease | Digestive | 1.05 | 0.925 – 1.2 | 0.437 | 264 | 2278 | exclusion | phecode |
| 558 | Noninfectious gastroenteritis | Digestive | 0.981 | 0.932 – 1.03 | 0.478 | 1667 | 13829 | exclusion | phecode |
| 559 | Ileostomy status | Digestive | 0.946 | 0.852 – 1.05 | 0.301 | 389 | 4605 | exclusion | phecode |
| 560 | Intestinal obstruction without mention of hernia | Digestive | 1 | 0.944 – 1.06 | 0.996 | 1328 | 12505 | exclusion | phecode |
| 560.1 | Paralytic ileus | Digestive | 1.01 | 0.933 – 1.09 | 0.811 | 675 | 7462 | exclusion | phecode |
| 560.2 | Impaction of intestine | Digestive | 0.971 | 0.837 – 1.12 | 0.692 | 189 | 2026 | exclusion | phecode |
| 560.3 | Peritoneal or intestinal adhesions | Digestive | 1.07 | 0.893 – 1.29 | 0.456 | 130 | 1294 | exclusion | phecode |
| 560.4 | Other intestinal obstruction | Digestive | 1.05 | 0.97 – 1.13 | 0.248 | 757 | 8069 | exclusion | phecode |
| 561 | Symptoms involving digestive system | Digestive | 0.99 | 0.934 – 1.05 | 0.738 | 1309 | 11261 | exclusion | phecode |
| 562 | Diverticulosis and diverticulitis | Digestive | 0.975 | 0.934 – 1.02 | 0.253 | 2822 | 11553 | exclusion | phecode |
| 562.1 | Diverticulosis | Digestive | 0.977 | 0.936 – 1.02 | 0.295 | 2802 | 11534 | exclusion | phecode |
| 562.2 | Diverticulitis | Digestive | 0.98 | 0.906 – 1.06 | 0.619 | 693 | 7361 | exclusion | phecode |
| 564 | Functional digestive disorders | Digestive | 0.994 | 0.963 – 1.03 | 0.706 | 5505 | 15048 | exclusion | phecode |
| 564.1 | Irritable Bowel Syndrome | Digestive | 0.969 | 0.921 – 1.02 | 0.234 | 1774 | 11934 | exclusion | phecode |
| 564.9 | Personal history of diseases of digestive system | Digestive | 1 | 0.947 – 1.06 | 0.989 | 1469 | 13146 | exclusion | phecode |
| 565 | Anal and rectal conditions | Digestive | 0.99 | 0.939 – 1.04 | 0.705 | 1590 | 15488 | exclusion | phecode |
| 565.1 | Anal and rectal polyp | Digestive | 0.946 | 0.866 – 1.03 | 0.217 | 554 | 6079 | exclusion | phecode |
| 567 | Peritonitis and retroperitoneal infections | Digestive | 0.95 | 0.871 – 1.04 | 0.252 | 578 | 6663 | exclusion | phecode |
| 568 | Other disorders of peritoneum | Digestive | 0.956 | 0.886 – 1.03 | 0.245 | 737 | 8318 | exclusion | phecode |
| 568.1 |
Peritoneal adhesions (postoperative)Peritoneal adhesions (postoperative) (postinfection)
|
Digestive | 0.992 | 0.906 – 1.09 | 0.856 | 524 | 6113 | exclusion | phecode |
| 569 | Other disorders of intestine | Digestive | 0.987 | 0.952 – 1.02 | 0.478 | 3701 | 18125 | exclusion | phecode |
| 569.1 | Toxic gastroenteritis and colitis | Digestive | 1.07 | 0.901 – 1.27 | 0.44 | 156 | 1621 | exclusion | phecode |
| 569.2 | Gastrointestinal complications | Digestive | 0.973 | 0.897 – 1.06 | 0.517 | 645 | 6942 | exclusion | phecode |
| 571 | Chronic liver disease and cirrhosis | Digestive | 0.99 | 0.946 – 1.04 | 0.669 | 2188 | 16216 | exclusion | phecode |
| 571.5 | Other chronic nonalcoholic liver disease | Digestive | 0.983 | 0.938 – 1.03 | 0.471 | 2073 | 16022 | exclusion | phecode |
| 571.51 | Cirrhosis of liver without mention of alcohol | Digestive | 0.986 | 0.891 – 1.09 | 0.792 | 417 | 4839 | exclusion | phecode |
| 571.6 | Primary biliary cirrhosis | Digestive | 0.84 | 0.679 – 1.04 | 0.109 | 96 | 868 | exclusion | phecode |
| 571.8 |
Liver abscess and sequelae of chronic liverLiver abscess and sequelae of chronic liver disease
|
Digestive | 1.03 | 0.934 – 1.14 | 0.52 | 405 | 4505 | exclusion | phecode |
| 571.81 | Portal hypertension | Digestive | 1.05 | 0.924 – 1.2 | 0.452 | 253 | 2739 | exclusion | phecode |
| 572 | Ascites (non malignant) | Digestive | 0.973 | 0.912 – 1.04 | 0.409 | 1031 | 11080 | exclusion | phecode |
| 573 | Other disorders of liver | Digestive | 0.982 | 0.942 – 1.02 | 0.393 | 2654 | 16885 | exclusion | phecode |
| 573.1 | Chronic passive congestion of liver | Digestive | 1.12 | 0.831 – 1.52 | 0.451 | 47 | 642 | exclusion | phecode |
| 573.2 | Liver replaced by transplant | Digestive | 0.963 | 0.806 – 1.15 | 0.679 | 130 | 1400 | exclusion | phecode |
| 573.3 | Hepatomegaly | Digestive | 1.07 | 0.933 – 1.22 | 0.337 | 231 | 2352 | exclusion | phecode |
| 573.4 | Acute and subacute necrosis of liver | Digestive | 1.2 | 1.01 – 1.43 | 0.0332 | 145 | 1545 | exclusion | phecode |
| 573.5 | Jaundice (not of newborn) | Digestive | 1.07 | 0.971 – 1.17 | 0.18 | 499 | 4576 | exclusion | phecode |
| 573.6 |
Nonspecific elevation of levels of transaminaseNonspecific elevation of levels of transaminase or lactic acid dehydrogenase [LDH]
|
Digestive | 0.952 | 0.899 – 1.01 | 0.0956 | 1320 | 13137 | exclusion | phecode |
| 573.7 | Abnormal results of function study of liver | Digestive | 0.977 | 0.925 – 1.03 | 0.395 | 1511 | 13846 | exclusion | phecode |
| 573.9 | Abnormal serum enzyme levels | Digestive | 0.98 | 0.937 – 1.03 | 0.383 | 2264 | 17087 | exclusion | phecode |
| 574 | Cholelithiasis and cholecystitis | Digestive | 0.963 | 0.914 – 1.01 | 0.154 | 1590 | 15168 | exclusion | phecode |
| 574.1 | Cholelithiasis | Digestive | 0.963 | 0.912 – 1.02 | 0.175 | 1473 | 14234 | exclusion | phecode |
| 574.11 | Cholelithiasis with acute cholecystitis | Digestive | 1.01 | 0.867 – 1.18 | 0.874 | 180 | 1640 | exclusion | phecode |
| 574.12 | Cholelithiasis with other cholecystitis | Digestive | 0.911 | 0.807 – 1.03 | 0.129 | 300 | 2663 | exclusion | phecode |
| 574.2 | Calculus of bile duct | Digestive | 0.915 | 0.828 – 1.01 | 0.0812 | 443 | 4220 | exclusion | phecode |
| 574.3 | Cholecystitis without cholelithiasis | Digestive | 0.898 | 0.809 – 0.996 | 0.0425 | 402 | 4013 | exclusion | phecode |
| 575 | Other biliary tract disease | Digestive | 0.938 | 0.88 – 0.999 | 0.0468 | 1095 | 11065 | exclusion | phecode |
| 575.1 | Cholangitis | Digestive | 1.01 | 0.863 – 1.17 | 0.939 | 180 | 1678 | exclusion | phecode |
| 575.2 | Obstruction of bile duct | Digestive | 0.906 | 0.803 – 1.02 | 0.104 | 297 | 2887 | exclusion | phecode |
| 575.6 | Cholesterolosis of gallbladder | Digestive | 0.818 | 0.679 – 0.984 | 0.0334 | 114 | 1063 | exclusion | phecode |
| 575.7 | Other disorders of gallbladder | Digestive | 0.956 | 0.869 – 1.05 | 0.357 | 476 | 4651 | exclusion | phecode |
| 575.8 | Other disorders of biliary tract | Digestive | 0.947 | 0.866 – 1.04 | 0.234 | 542 | 5503 | exclusion | phecode |
| 575.9 |
Nonspecific abnormal findings on radiologicalNonspecific abnormal findings on radiological and other examination of biliary tract
|
Digestive | 0.975 | 0.81 – 1.17 | 0.791 | 128 | 1289 | exclusion | phecode |
| 577 | Diseases of pancreas | Digestive | 0.94 | 0.88 – 1 | 0.0667 | 988 | 10687 | exclusion | phecode |
| 577.1 | Acute pancreatitis | Digestive | 0.966 | 0.883 – 1.06 | 0.457 | 519 | 5960 | exclusion | phecode |
| 577.2 | Chronic pancreatitis | Digestive | 0.968 | 0.832 – 1.13 | 0.669 | 178 | 2421 | exclusion | phecode |
| 577.3 | Cyst and pseudocyst of pancreas | Digestive | 0.93 | 0.819 – 1.06 | 0.259 | 265 | 2683 | exclusion | phecode |
| 578 | Gastrointestinal hemorrhage | Digestive | 1 | 0.958 – 1.05 | 0.935 | 2179 | 18773 | exclusion | phecode |
| 578.1 | Hematemesis | Digestive | 0.951 | 0.827 – 1.09 | 0.477 | 213 | 2433 | exclusion | phecode |
| 578.2 | Blood in stool | Digestive | 1.02 | 0.962 – 1.08 | 0.509 | 1272 | 13074 | exclusion | phecode |
| 578.8 | Hemorrhage of rectum and anus | Digestive | 1 | 0.943 – 1.07 | 0.902 | 1124 | 11081 | exclusion | phecode |
| 578.9 | Hemorrhage of gastrointestinal tract | Digestive | 0.967 | 0.894 – 1.05 | 0.401 | 682 | 7363 | exclusion | phecode |
| 579 | Other symptoms involving abdomen and pelvis | Digestive | 0.981 | 0.936 – 1.03 | 0.406 | 2089 | 17253 | exclusion | phecode |
| 579.2 | Splenomegaly | Digestive | 1.04 | 0.928 – 1.16 | 0.535 | 354 | 3585 | exclusion | phecode |
| 579.8 | Nonspecific abnormal findings in stool contents | Digestive | 0.966 | 0.893 – 1.05 | 0.391 | 681 | 6850 | exclusion | phecode |
| 580 | Nephritis; nephrosis; renal sclerosis | Genitourinary | 1.01 | 0.943 – 1.09 | 0.73 | 885 | 7670 | exclusion | phecode |
| 580.1 | Glomerulonephritis | Genitourinary | 1.15 | 0.991 – 1.33 | 0.0664 | 201 | 2032 | exclusion | phecode |
| 580.11 | Proliferative glomerulonephritis | Genitourinary | 1.27 | 1.01 – 1.59 | 0.0386 | 82 | 744 | exclusion | phecode |
| 580.12 | Non-proliferative glomerulonephritis | Genitourinary | 1.27 | 0.966 – 1.67 | 0.0872 | 56 | 564 | exclusion | phecode |
| 580.13 | Acute glomerulonephritis, NOS | Genitourinary | 0.895 | 0.593 – 1.35 | 0.598 | 26 | 313 | exclusion | phecode |
| 580.14 | Chronic glomerulonephritis, NOS | Genitourinary | 1.16 | 0.977 – 1.38 | 0.0886 | 146 | 1383 | exclusion | phecode |
| 580.2 |
Nephrotic syndrome without mention ofNephrotic syndrome without mention of glomerulonephritis
|
Genitourinary | 1.23 | 1.01 – 1.49 | 0.0377 | 115 | 1123 | exclusion | phecode |
| 580.3 |
Nephritis and nephropathy without mention ofNephritis and nephropathy without mention of glomerulonephritis
|
Genitourinary | 0.993 | 0.918 – 1.07 | 0.866 | 727 | 5894 | exclusion | phecode |
| 580.31 |
Nephritis and nephropathy in diseasesNephritis and nephropathy in diseases classified elsewhere
|
Genitourinary | 1.03 | 0.938 – 1.14 | 0.516 | 488 | 3527 | exclusion | phecode |
| 580.32 |
Nephritis and nephropathy with pathologicalNephritis and nephropathy with pathological lesion
|
Genitourinary | 0.967 | 0.863 – 1.08 | 0.565 | 329 | 3375 | exclusion | phecode |
| 580.4 | Renal sclerosis, NOS | Genitourinary | 1.06 | 0.897 – 1.25 | 0.493 | 149 | 1713 | exclusion | phecode |
| 585 | Renal failure | Genitourinary | 1.01 | 0.97 – 1.05 | 0.663 | 3175 | 16577 | exclusion | phecode |
| 585.1 | Acute renal failure | Genitourinary | 0.984 | 0.935 – 1.04 | 0.532 | 1760 | 13569 | exclusion | phecode |
| 585.2 | Renal failure NOS | Genitourinary | 1.15 | 1.04 – 1.29 | 0.00973 | 366 | 3944 | exclusion | phecode |
| 585.3 | Chronic renal failure [CKD] | Genitourinary | 1.02 | 0.974 – 1.07 | 0.412 | 2345 | 14810 | exclusion | phecode |
| 585.31 | Renal dialysis | Genitourinary | 1.04 | 0.93 – 1.17 | 0.476 | 327 | 3632 | exclusion | phecode |
| 585.32 | End stage renal disease | Genitourinary | 1.01 | 0.92 – 1.12 | 0.784 | 463 | 4797 | exclusion | phecode |
| 585.33 | Chronic Kidney Disease, Stage III | Genitourinary | 1 | 0.945 – 1.06 | 0.964 | 1358 | 10263 | exclusion | phecode |
| 585.34 | Chronic Kidney Disease, Stage IV | Genitourinary | 1.04 | 0.942 – 1.15 | 0.433 | 427 | 4383 | exclusion | phecode |
| 585.4 | Chronic kidney disease, Stage I or II | Genitourinary | 1.07 | 0.974 – 1.16 | 0.166 | 545 | 5492 | exclusion | phecode |
| 586 | Other disorders of the kidney and ureters | Genitourinary | 0.99 | 0.954 – 1.03 | 0.618 | 3461 | 17878 | exclusion | phecode |
| 586.1 | Anatomical abnormatilies of kidney and ureters | Genitourinary | 1.04 | 0.885 – 1.22 | 0.65 | 169 | 1817 | exclusion | phecode |
| 586.11 | Small kidney | Genitourinary | 1.06 | 0.86 – 1.32 | 0.565 | 94 | 1117 | exclusion | phecode |
| 586.12 | Vesicoureteral reflux | Genitourinary | 1.06 | 0.822 – 1.37 | 0.652 | 70 | 722 | exclusion | phecode |
| 586.2 | Cyst of kidney, acquired | Genitourinary | 0.913 | 0.839 – 0.993 | 0.0347 | 594 | 5986 | exclusion | phecode |
| 586.3 | Vascular disorders of kidney/hypertrophy | Genitourinary | 1.31 | 1.05 – 1.64 | 0.0177 | 86 | 878 | exclusion | phecode |
| 586.4 | Stricture/obstruction of ureter | Genitourinary | 0.967 | 0.898 – 1.04 | 0.379 | 795 | 8182 | exclusion | phecode |
| 587 | Kidney replaced by transpant | Genitourinary | 1.04 | 0.938 – 1.15 | 0.463 | 418 | 3973 | exclusion | phecode |
| 588 | Disorders resulting from impaired renal function | Genitourinary | 1.05 | 0.959 – 1.16 | 0.276 | 487 | 4598 | exclusion | phecode |
| 588.1 | Renal osteodystrophy | Genitourinary | 1.06 | 0.891 – 1.25 | 0.532 | 152 | 1384 | exclusion | phecode |
| 588.2 | Secondary hyperparathyroidism (of renal origin) | Genitourinary | 1.04 | 0.938 – 1.16 | 0.427 | 385 | 3556 | exclusion | phecode |
| 589 | Abnormal results of function study of kidney | Genitourinary | 1.04 | 0.948 – 1.15 | 0.387 | 469 | 4758 | exclusion | phecode |
| 590 | Pyelonephritis | Genitourinary | 1.01 | 0.932 – 1.09 | 0.847 | 701 | 7425 | exclusion | phecode |
| 591 | Urinary tract infection | Genitourinary | 1 | 0.968 – 1.03 | 0.967 | 4963 | 16435 | exclusion | phecode |
| 592 | Cystitis and urethritis | Genitourinary | 0.968 | 0.917 – 1.02 | 0.231 | 1538 | 12377 | exclusion | phecode |
| 592.1 | Cystitis | Genitourinary | 0.961 | 0.91 – 1.02 | 0.163 | 1467 | 11915 | exclusion | phecode |
| 592.11 | Acute cystitis | Genitourinary | 0.96 | 0.897 – 1.03 | 0.25 | 935 | 8517 | exclusion | phecode |
| 592.12 | Chronic cystitis | Genitourinary | 0.941 | 0.784 – 1.13 | 0.512 | 128 | 1151 | exclusion | phecode |
| 592.13 | Chronic interstitial cystitis | Genitourinary | 1.02 | 0.886 – 1.17 | 0.795 | 228 | 2362 | exclusion | phecode |
| 592.2 | Urethritis and urethral syndrome | Genitourinary | 1.09 | 0.881 – 1.34 | 0.441 | 97 | 1076 | exclusion | phecode |
| 593 | Hematuria | Genitourinary | 1.02 | 0.977 – 1.07 | 0.351 | 2285 | 16155 | exclusion | phecode |
| 593.1 | Gross hematuria | Genitourinary | 1.02 | 0.943 – 1.11 | 0.606 | 693 | 6767 | exclusion | phecode |
| 593.2 | Microscopic hematuria | Genitourinary | 1.01 | 0.92 – 1.11 | 0.841 | 507 | 5080 | exclusion | phecode |
| 594 | Urinary calculus | Genitourinary | 1.01 | 0.977 – 1.05 | 0.467 | 3323 | 19248 | exclusion | phecode |
| 594.1 | Calculus of kidney | Genitourinary | 1.01 | 0.974 – 1.05 | 0.546 | 3126 | 19149 | exclusion | phecode |
| 594.2 | Calculus of lower urinary tract | Genitourinary | 1.13 | 0.962 – 1.33 | 0.137 | 176 | 1509 | exclusion | phecode |
| 594.3 | Calculus of ureter | Genitourinary | 0.992 | 0.916 – 1.07 | 0.845 | 695 | 6525 | exclusion | phecode |
| 594.8 | Renal colic | Genitourinary | 1.09 | 0.931 – 1.26 | 0.295 | 180 | 1804 | exclusion | phecode |
| 595 | Hydronephrosis | Genitourinary | 0.972 | 0.902 – 1.05 | 0.461 | 783 | 7933 | exclusion | phecode |
| 596 | Other disorders of bladder | Genitourinary | 1.01 | 0.95 – 1.06 | 0.835 | 1354 | 13405 | exclusion | phecode |
| 596.1 | Bladder neck obstruction | Genitourinary | 0.972 | 0.826 – 1.14 | 0.732 | 170 | 1536 | exclusion | phecode |
| 596.5 | Functional disorders of bladder | Genitourinary | 1.03 | 0.955 – 1.1 | 0.477 | 815 | 8339 | exclusion | phecode |
| 597 | Other disorders of urethra and urinary tract | Genitourinary | 1.02 | 0.938 – 1.11 | 0.616 | 567 | 5589 | exclusion | phecode |
| 597.1 | Urethral stricture (not specified as infectious) | Genitourinary | 1.04 | 0.924 – 1.18 | 0.494 | 290 | 2835 | exclusion | phecode |
| 597.2 | Urinary complications NEC | Genitourinary | 0.99 | 0.902 – 1.09 | 0.841 | 481 | 4846 | exclusion | phecode |
| 597.8 | Urethral hypermobility/ISD | Genitourinary | 1.11 | 0.901 – 1.37 | 0.326 | 93 | 949 | exclusion | phecode |
| 598 | Abnormal findings on examination of urine | Genitourinary | 1.13 | 0.865 – 1.47 | 0.378 | 64 | 665 | exclusion | phecode |
| 598.4 | Other cells and casts in urine | Genitourinary | 1.09 | 0.821 – 1.44 | 0.553 | 58 | 574 | exclusion | phecode |
| 599 | Other symptoms/disorders or the urinary system | Genitourinary | 1.01 | 0.985 – 1.04 | 0.347 | 6934 | 15919 | exclusion | phecode |
| 599.1 | Urinary obstruction | Genitourinary | 0.911 | 0.811 – 1.02 | 0.117 | 316 | 2840 | exclusion | phecode |
| 599.2 | Retention of urine | Genitourinary | 1.02 | 0.975 – 1.07 | 0.387 | 2307 | 14239 | exclusion | phecode |
| 599.3 | Dysuria | Genitourinary | 0.997 | 0.953 – 1.04 | 0.895 | 2281 | 14231 | exclusion | phecode |
| 599.4 | Urinary incontinence | Genitourinary | 1.03 | 0.991 – 1.08 | 0.126 | 2731 | 13581 | exclusion | phecode |
| 599.5 | Frequency of urination and polyuria | Genitourinary | 1.01 | 0.968 – 1.05 | 0.647 | 2700 | 14674 | exclusion | phecode |
| 599.6 | Oliguria and anuria | Genitourinary | 1.07 | 0.936 – 1.21 | 0.335 | 252 | 2702 | exclusion | phecode |
| 599.7 | Urethral discharge | Genitourinary | 1.17 | 0.9 – 1.53 | 0.239 | 61 | 508 | exclusion | phecode |
| 599.8 | Other symptoms involving urinary system | Genitourinary | 0.993 | 0.95 – 1.04 | 0.75 | 2505 | 14178 | exclusion | phecode |
| 599.9 | Other abnormality of urination | Genitourinary | 1.01 | 0.955 – 1.06 | 0.758 | 1524 | 12363 | exclusion | phecode |
| 600 | Hyperplasia of prostate | Genitourinary | 0.996 | 0.937 – 1.06 | 0.896 | 1660 | 4841 | exclusion | phecode |
| 601 | Inflammatory diseases of prostate | Genitourinary | 0.997 | 0.908 – 1.1 | 0.958 | 504 | 4156 | exclusion | phecode |
| 601.1 | Prostatitis | Genitourinary | 1.06 | 0.924 – 1.22 | 0.406 | 234 | 1880 | exclusion | phecode |
| 601.11 | Acute prostatitis | Genitourinary | 0.851 | 0.64 – 1.13 | 0.268 | 57 | 505 | exclusion | phecode |
| 601.12 | Chronic prostatitis | Genitourinary | 0.949 | 0.717 – 1.26 | 0.715 | 51 | 397 | exclusion | phecode |
| 601.3 | Orchitis and epididymitis | Genitourinary | 1.08 | 0.931 – 1.25 | 0.319 | 201 | 1744 | exclusion | phecode |
| 601.4 | Balanoposthitis | Genitourinary | 1.01 | 0.746 – 1.36 | 0.956 | 52 | 511 | exclusion | phecode |
| 601.8 |
Other inflammatory disorders of male genitalOther inflammatory disorders of male genital organs
|
Genitourinary | 0.804 | 0.627 – 1.03 | 0.086 | 70 | 669 | exclusion | phecode |
| 602 | Other disorders of prostate | Genitourinary | 0.96 | 0.811 – 1.14 | 0.634 | 168 | 1297 | exclusion | phecode |
| 602.3 | Dysplasia of prostate | Genitourinary | 0.994 | 0.674 – 1.47 | 0.976 | 39 | 275 | exclusion | phecode |
| 603 | Other disorders of testis | Genitourinary | 1.1 | 0.954 – 1.28 | 0.186 | 202 | 1912 | exclusion | phecode |
| 603.1 | Hydrocele | Genitourinary | 0.988 | 0.818 – 1.19 | 0.899 | 120 | 1214 | exclusion | phecode |
| 603.2 | Spermatocele | Genitourinary | 1.26 | 0.999 – 1.59 | 0.0507 | 86 | 670 | exclusion | phecode |
| 604 | Disorders of penis | Genitourinary | 1.05 | 0.928 – 1.18 | 0.45 | 293 | 2859 | exclusion | phecode |
| 604.1 | Redundant prepuce and phimosis/BXO | Genitourinary | 1.22 | 0.906 – 1.65 | 0.189 | 51 | 612 | exclusion | phecode |
| 604.3 | Peyronie's disease | Genitourinary | 1.16 | 0.952 – 1.42 | 0.139 | 105 | 902 | exclusion | phecode |
| 605 | Erectile dysfunction [ED] | Genitourinary | 1.03 | 0.976 – 1.09 | 0.261 | 1671 | 5463 | exclusion | phecode |
| 608 | Other disorders of male genital organs | Genitourinary | 0.986 | 0.914 – 1.06 | 0.714 | 792 | 6201 | exclusion | phecode |
| 609 | Male infertility and abnormal spermatozoa | Genitourinary | 1.07 | 0.944 – 1.22 | 0.281 | 276 | 2079 | exclusion | phecode |
| 609.1 | Infertility, male | Genitourinary | 1.04 | 0.899 – 1.21 | 0.578 | 210 | 1558 | exclusion | phecode |
| 609.11 | Azoospermia and oligospermia | Genitourinary | 0.993 | 0.75 – 1.31 | 0.96 | 63 | 503 | exclusion | phecode |
| 609.2 | Abnormal spermatozoa | Genitourinary | 1.13 | 0.918 – 1.39 | 0.247 | 93 | 688 | exclusion | phecode |
| 610 | Benign mammary dysplasias | Genitourinary | 0.972 | 0.926 – 1.02 | 0.256 | 2127 | 9047 | exclusion | phecode |
| 610.1 | Cystic mastopathy | Genitourinary | 0.953 | 0.889 – 1.02 | 0.169 | 960 | 7444 | exclusion | phecode |
| 610.2 | Fibroadenosis of breast | Genitourinary | 0.944 | 0.665 – 1.34 | 0.747 | 36 | 318 | exclusion | phecode |
| 610.4 | Benign neoplasm of breast | Genitourinary | 0.963 | 0.912 – 1.02 | 0.17 | 1637 | 8956 | exclusion | phecode |
| 610.8 | Other specified benign mammary dysplasias | Genitourinary | 0.943 | 0.872 – 1.02 | 0.145 | 743 | 6387 | exclusion | phecode |
| 611 | Abnormal findings on mammogram or breast exam | Genitourinary | 0.993 | 0.954 – 1.03 | 0.728 | 3483 | 9964 | exclusion | phecode |
| 611.1 | Abnormal mammogram | Genitourinary | 0.961 | 0.92 – 1 | 0.0749 | 2879 | 8550 | exclusion | phecode |
| 611.11 | Mammographic microcalcification | Genitourinary | 0.996 | 0.918 – 1.08 | 0.921 | 667 | 5363 | exclusion | phecode |
| 611.3 | Lump or mass in breast | Genitourinary | 1.01 | 0.958 – 1.06 | 0.795 | 2050 | 9922 | exclusion | phecode |
| 612 |
Breast conditions, congenital or relating toBreast conditions, congenital or relating to hormones
|
Genitourinary | 1.02 | 0.934 – 1.11 | 0.678 | 611 | 5463 | exclusion | phecode |
| 612.1 | Galactorrhea | Genitourinary | 1.04 | 0.825 – 1.31 | 0.747 | 84 | 753 | exclusion | phecode |
| 612.2 | Hypertrophy of breast (Gynecomastia) | Genitourinary | 1.03 | 0.928 – 1.13 | 0.622 | 455 | 4120 | exclusion | phecode |
| 612.3 | Congenital anomalies of breast | Genitourinary | 0.956 | 0.718 – 1.27 | 0.761 | 57 | 456 | exclusion | phecode |
| 613 | Other nonmalignant breast conditions | Genitourinary | 0.998 | 0.953 – 1.05 | 0.934 | 2193 | 12050 | exclusion | phecode |
| 613.1 | Inflammatory disease of breast | Genitourinary | 0.928 | 0.824 – 1.04 | 0.216 | 320 | 3193 | exclusion | phecode |
| 613.5 | Mastodynia | Genitourinary | 0.991 | 0.925 – 1.06 | 0.805 | 904 | 8627 | exclusion | phecode |
| 613.7 | Other signs and symptoms in breast | Genitourinary | 0.971 | 0.882 – 1.07 | 0.54 | 480 | 4778 | exclusion | phecode |
| 613.8 | Other specified disorders of breast | Genitourinary | 1.01 | 0.921 – 1.1 | 0.857 | 540 | 4965 | exclusion | phecode |
| 613.9 | Breast disorder NOS | Genitourinary | 0.995 | 0.926 – 1.07 | 0.902 | 852 | 7457 | exclusion | phecode |
| 614 | Inflammatory diseases of female pelvic organs | Genitourinary | 1.05 | 0.996 – 1.1 | 0.0725 | 2025 | 10953 | exclusion | phecode |
| 614.1 |
Pelvic peritoneal adhesions, femalePelvic peritoneal adhesions, female (postoperative) (postinfection)
|
Genitourinary | 1.05 | 0.905 – 1.23 | 0.499 | 176 | 1885 | exclusion | phecode |
| 614.3 | Pelvic inflammatory disease (PID) | Genitourinary | 0.992 | 0.865 – 1.14 | 0.904 | 218 | 2700 | exclusion | phecode |
| 614.31 | Acute inflammatory pelvic disease | Genitourinary | 1.02 | 0.764 – 1.37 | 0.875 | 43 | 573 | exclusion | phecode |
| 614.32 | Chronic inflammatory pelvic disease | Genitourinary | 0.893 | 0.726 – 1.1 | 0.282 | 93 | 993 | exclusion | phecode |
| 614.33 | Pelvic inflammatory disease, NOS | Genitourinary | 0.979 | 0.805 – 1.19 | 0.835 | 103 | 1400 | exclusion | phecode |
| 614.4 | Inflammatory diseases of uterus, except cervix | Genitourinary | 0.901 | 0.734 – 1.11 | 0.317 | 103 | 916 | exclusion | phecode |
| 614.5 |
Inflammatory disease of cervix, vagina, andInflammatory disease of cervix, vagina, and vulva
|
Genitourinary | 1.06 | 1.01 – 1.12 | 0.0191 | 1757 | 10894 | exclusion | phecode |
| 614.51 | Cervicitis and endocervicitis | Genitourinary | 0.939 | 0.791 – 1.11 | 0.472 | 143 | 1439 | exclusion | phecode |
| 614.52 | Vaginitis and vulvovaginitis | Genitourinary | 1.08 | 1.02 – 1.14 | 0.00856 | 1506 | 10561 | exclusion | phecode |
| 614.53 | Cyst or abscess of Bartholin's gland | Genitourinary | 1.12 | 0.881 – 1.43 | 0.354 | 69 | 757 | exclusion | phecode |
| 614.54 | Abscess or ulceration of vulva | Genitourinary | 1.03 | 0.847 – 1.24 | 0.787 | 120 | 1227 | exclusion | phecode |
| 615 | Endometriosis | Genitourinary | 0.979 | 0.912 – 1.05 | 0.556 | 893 | 8015 | exclusion | phecode |
| 618 | Genital prolapse | Genitourinary | 1.01 | 0.954 – 1.08 | 0.648 | 1159 | 9574 | exclusion | phecode |
| 618.1 | Prolapse of vaginal walls | Genitourinary | 1.02 | 0.947 – 1.1 | 0.613 | 803 | 7121 | exclusion | phecode |
| 618.2 | Uterine/Uterovaginal prolapse | Genitourinary | 1.03 | 0.915 – 1.16 | 0.643 | 319 | 2855 | exclusion | phecode |
| 618.5 | Prolapse of vaginal vault after hysterectomy | Genitourinary | 1.03 | 0.884 – 1.2 | 0.703 | 186 | 1627 | exclusion | phecode |
| 618.6 | Vaginal enterocele, congenital or acquired | Genitourinary | 0.907 | 0.789 – 1.04 | 0.168 | 222 | 2294 | exclusion | phecode |
| 619 | Noninflammatory female genital disorders | Genitourinary | 1 | 0.961 – 1.04 | 0.997 | 3331 | 10259 | exclusion | phecode |
| 619.1 |
Noninflammatory disorders of ovary, fallopianNoninflammatory disorders of ovary, fallopian tube, and broad ligament
|
Genitourinary | 0.985 | 0.911 – 1.07 | 0.708 | 728 | 6702 | exclusion | phecode |
| 619.2 | Disorders of uterus, NEC | Genitourinary | 0.959 | 0.858 – 1.07 | 0.457 | 370 | 3205 | exclusion | phecode |
| 619.3 | Noninflammatory disorders of cervix | Genitourinary | 1.01 | 0.885 – 1.14 | 0.927 | 273 | 2565 | exclusion | phecode |
| 619.4 | Noninflammatory disorders of vagina | Genitourinary | 0.997 | 0.943 – 1.05 | 0.913 | 1494 | 10090 | exclusion | phecode |
| 619.5 | Noninflammatory disorders of vulva and perineum | Genitourinary | 1.05 | 0.97 – 1.14 | 0.216 | 662 | 6365 | exclusion | phecode |
| 620 | Dysplasia of female genital organs | Genitourinary | 1.1 | 0.944 – 1.29 | 0.218 | 188 | 2053 | exclusion | phecode |
| 620.1 | Dysplasia of cervix | Genitourinary | 0.971 | 0.783 – 1.2 | 0.788 | 93 | 931 | exclusion | phecode |
| 621 | Endometrial hyperplasia | Genitourinary | 0.91 | 0.804 – 1.03 | 0.137 | 284 | 2315 | exclusion | phecode |
| 622 | Polyp of female genital organs | Genitourinary | 1.04 | 0.967 – 1.11 | 0.311 | 948 | 7548 | exclusion | phecode |
| 622.1 | Polyp of corpus uteri | Genitourinary | 1.02 | 0.945 – 1.11 | 0.58 | 739 | 5902 | exclusion | phecode |
| 622.2 | Mucous polyp of cervix | Genitourinary | 1.05 | 0.93 – 1.19 | 0.424 | 305 | 2373 | exclusion | phecode |
| 623 | Hypertrophy of female genital organs | Genitourinary | 1.02 | 0.926 – 1.12 | 0.704 | 480 | 4399 | exclusion | phecode |
| 624 | Symptoms involving female genital tract | Genitourinary | 0.995 | 0.923 – 1.07 | 0.905 | 765 | 6969 | exclusion | phecode |
| 624.1 | Dystrophy of female genital tract | Genitourinary | 0.935 | 0.774 – 1.13 | 0.486 | 120 | 1130 | exclusion | phecode |
| 624.2 | Atrophy of female genital tract | Genitourinary | 1.2 | 0.851 – 1.7 | 0.296 | 32 | 344 | exclusion | phecode |
| 624.9 | stress incontinence, female | Genitourinary | 1.08 | 1.01 – 1.15 | 0.0248 | 1048 | 8160 | exclusion | phecode |
| 625 |
Pain and other symptoms associated with femalePain and other symptoms associated with female genital organs
|
Genitourinary | 0.98 | 0.941 – 1.02 | 0.336 | 3225 | 9577 | exclusion | phecode |
| 625.1 | Dyspareunia | Genitourinary | 1.02 | 0.946 – 1.11 | 0.558 | 698 | 6805 | exclusion | phecode |
| 626 |
Disorders of menstruation and other abnormalDisorders of menstruation and other abnormal bleeding from female genital tract
|
Genitourinary | 1.01 | 0.969 – 1.05 | 0.657 | 3588 | 8354 | exclusion | phecode |
| 626.1 | Irregular menstrual cycle/bleeding | Genitourinary | 1.01 | 0.962 – 1.05 | 0.749 | 2635 | 7810 | exclusion | phecode |
| 626.11 | Absent or infrequent menstruation | Genitourinary | 0.94 | 0.863 – 1.02 | 0.148 | 647 | 4746 | exclusion | phecode |
| 626.12 | Excessive or frequent menstruation | Genitourinary | 1.01 | 0.952 – 1.08 | 0.708 | 1285 | 6455 | exclusion | phecode |
| 626.13 | Irregular menstrual cycle | Genitourinary | 1.02 | 0.96 – 1.09 | 0.488 | 1193 | 6588 | exclusion | phecode |
| 626.14 | Irregular menstrual bleeding | Genitourinary | 1.03 | 0.946 – 1.12 | 0.487 | 610 | 4829 | exclusion | phecode |
| 626.15 | Infertility, female, associated with anovulation | Genitourinary | 0.934 | 0.821 – 1.06 | 0.296 | 276 | 2059 | exclusion | phecode |
| 626.2 | Dysmenorrhea | Genitourinary | 0.992 | 0.918 – 1.07 | 0.83 | 776 | 5421 | exclusion | phecode |
| 626.4 | Premenstrual tension syndromes | Genitourinary | 1.14 | 0.98 – 1.33 | 0.0893 | 193 | 1736 | exclusion | phecode |
| 626.8 | Infertility, female | Genitourinary | 0.916 | 0.836 – 1 | 0.0624 | 554 | 3687 | exclusion | phecode |
| 627 | Menopausal and postmenopausal disorders | Genitourinary | 0.993 | 0.948 – 1.04 | 0.748 | 2631 | 7569 | exclusion | phecode |
| 627.1 | Postmenopausal bleeding | Genitourinary | 0.969 | 0.893 – 1.05 | 0.444 | 685 | 5252 | exclusion | phecode |
| 627.2 | Symptomatic menopause | Genitourinary | 0.998 | 0.946 – 1.05 | 0.945 | 1722 | 7084 | exclusion | phecode |
| 627.21 | Symptomatic artificial menopause | Genitourinary | 0.984 | 0.793 – 1.22 | 0.885 | 89 | 787 | exclusion | phecode |
| 627.22 |
Need for Hormone replacement therapyNeed for Hormone replacement therapy (postmenopausal)
|
Genitourinary | 1.01 | 0.873 – 1.17 | 0.874 | 201 | 1782 | exclusion | phecode |
| 627.3 | Postmenopausal atrophic vaginitis | Genitourinary | 1 | 0.919 – 1.09 | 0.95 | 585 | 4822 | exclusion | phecode |
| 627.4 | Premenopausal menorrhagia | Genitourinary | 1.14 | 0.982 – 1.31 | 0.086 | 208 | 1847 | exclusion | phecode |
| 627.5 | Premature menopause and other ovarian failure | Genitourinary | 0.955 | 0.82 – 1.11 | 0.557 | 191 | 1626 | exclusion | phecode |
| 628 | Ovarian cyst | Genitourinary | 0.972 | 0.911 – 1.04 | 0.395 | 1115 | 7406 | exclusion | phecode |
| 634 | Miscarriage; stillbirth | Pregnancy Complications | 0.859 | 0.78 – 0.946 | 0.00207 | 460 | 4483 | exclusion | phecode |
| 634.1 | Missed abortion/Hydatidiform mole | Pregnancy Complications | 0.829 | 0.71 – 0.967 | 0.0174 | 181 | 1506 | exclusion | phecode |
| 634.3 | Ectopic pregnancy | Pregnancy Complications | 0.749 | 0.569 – 0.987 | 0.0403 | 57 | 653 | exclusion | phecode |
| 635 |
Hemorrhage during pregnancy; childbirth andHemorrhage during pregnancy; childbirth and postpartum
|
Pregnancy Complications | 0.978 | 0.875 – 1.09 | 0.699 | 357 | 2994 | exclusion | phecode |
| 635.2 |
Antepartum hemorrhage, abruptio placentae, andAntepartum hemorrhage, abruptio placentae, and placenta previa
|
Pregnancy Complications | 0.969 | 0.845 – 1.11 | 0.645 | 234 | 2004 | exclusion | phecode |
| 635.3 | Placenta previa and abruptio placenta | Pregnancy Complications | 0.919 | 0.788 – 1.07 | 0.284 | 187 | 1609 | exclusion | phecode |
| 636 |
Early or threatened labor; hemorrhage in earlyEarly or threatened labor; hemorrhage in early pregnancy
|
Pregnancy Complications | 0.968 | 0.889 – 1.05 | 0.461 | 630 | 4490 | exclusion | phecode |
| 636.1 | Threatened premature labor | Pregnancy Complications | 1.1 | 0.952 – 1.26 | 0.203 | 220 | 2131 | exclusion | phecode |
| 636.2 | Early onset of delivery | Pregnancy Complications | 0.979 | 0.835 – 1.15 | 0.799 | 163 | 1556 | exclusion | phecode |
| 636.3 | Hemorrhage in early pregnancy | Pregnancy Complications | 1.01 | 0.89 – 1.15 | 0.839 | 257 | 2399 | exclusion | phecode |
| 636.8 | Cervical incompetence | Pregnancy Complications | 1.31 | 0.95 – 1.81 | 0.0991 | 43 | 422 | exclusion | phecode |
| 637 |
Short gestation; low birth weight; and fetalShort gestation; low birth weight; and fetal growth retardation
|
Pregnancy Complications | 1.15 | 0.85 – 1.54 | 0.371 | 51 | 460 | exclusion | phecode |
| 642 |
Hypertension complicating pregnancyHypertension complicating pregnancy, childbirth, and the puerperium
|
Pregnancy Complications | 0.917 | 0.819 – 1.03 | 0.132 | 341 | 3222 | exclusion | phecode |
| 642.1 | Preeclampsia and eclampsia | Pregnancy Complications | 0.904 | 0.771 – 1.06 | 0.212 | 175 | 1686 | exclusion | phecode |
| 643 | Excessive vomiting in pregnancy | Pregnancy Complications | 1.06 | 0.899 – 1.25 | 0.485 | 152 | 1439 | exclusion | phecode |
| 643.1 | Hyperemesis gravidarum | Pregnancy Complications | 1.18 | 0.921 – 1.51 | 0.193 | 69 | 663 | exclusion | phecode |
| 644 | Anemia during pregnancy | Pregnancy Complications | 1.05 | 0.875 – 1.25 | 0.618 | 137 | 1273 | exclusion | phecode |
| 646 | Other complications of pregnancy NEC | Pregnancy Complications | 1.04 | 0.945 – 1.14 | 0.421 | 493 | 3755 | exclusion | phecode |
| 647 |
Infectious and parasitic complicationsInfectious and parasitic complications affecting pregnancy
|
Pregnancy Complications | 1.03 | 0.847 – 1.25 | 0.777 | 118 | 1207 | exclusion | phecode |
| 647.1 |
Infections of genitourinary tract duringInfections of genitourinary tract during pregnancy
|
Pregnancy Complications | 1.28 | 1.05 – 1.56 | 0.0131 | 112 | 1259 | exclusion | phecode |
| 647.3 | Major puerperal infection | Pregnancy Complications | 0.956 | 0.698 – 1.31 | 0.776 | 40 | 396 | exclusion | phecode |
| 649 |
Other conditions or status of the motherOther conditions or status of the mother complicating pregnancy, childbirth, or the puerperium
|
Pregnancy Complications | 0.993 | 0.918 – 1.07 | 0.863 | 753 | 4576 | exclusion | phecode |
| 649.1 |
Diabetes or abnormal glucose toleranceDiabetes or abnormal glucose tolerance complicating pregnancy
|
Pregnancy Complications | 1.03 | 0.923 – 1.15 | 0.61 | 377 | 3177 | exclusion | phecode |
| 653 |
Problems associated with amniotic cavity andProblems associated with amniotic cavity and membranes
|
Pregnancy Complications | 1 | 0.898 – 1.12 | 0.944 | 349 | 3034 | exclusion | phecode |
| 654.1 |
Abnormality of organs and soft tissues ofAbnormality of organs and soft tissues of pelvis complicating pregnancy, childbirth, or the puerperium
|
Pregnancy Complications | 1.2 | 1 – 1.44 | 0.0484 | 136 | 1142 | exclusion | phecode |
| 654.2 | Rhesus isoimmunization in pregnancy | Pregnancy Complications | 1.04 | 0.858 – 1.27 | 0.679 | 113 | 1141 | exclusion | phecode |
| 655 |
Known or suspected fetal abnormality affectingKnown or suspected fetal abnormality affecting management of mother
|
Pregnancy Complications | 0.96 | 0.896 – 1.03 | 0.241 | 1014 | 5669 | exclusion | phecode |
| 655.1 | Abnormality in fetal heart rate or rhythm | Pregnancy Complications | 1.05 | 0.941 – 1.17 | 0.379 | 371 | 3088 | exclusion | phecode |
| 656 | Other perinatal conditions of fetus or newborn | Pregnancy Complications | 1.08 | 0.984 – 1.18 | 0.105 | 527 | 3958 | exclusion | phecode |
| 656.2 | Respiratory conditions of fetus and newborn | Pregnancy Complications | 1.29 | 0.925 – 1.79 | 0.135 | 36 | 340 | exclusion | phecode |
| 669 | Complications of labor and delivery NEC | Pregnancy Complications | 0.977 | 0.891 – 1.07 | 0.629 | 534 | 3863 | exclusion | phecode |
| 671 |
Venous/cerebrovascular complications embolismVenous/cerebrovascular complications embolism in pregnancy and the puerperium
|
Pregnancy Complications | 1.05 | 0.872 – 1.25 | 0.63 | 132 | 1316 | exclusion | phecode |
| 674 | Other complications of the puerperium NEC | Pregnancy Complications | 1.11 | 0.889 – 1.38 | 0.365 | 100 | 910 | exclusion | phecode |
| 676 |
Other disorders of the breast associated withOther disorders of the breast associated with childbirth and disorders of lactation
|
Pregnancy Complications | 1 | 0.824 – 1.22 | 0.99 | 122 | 1024 | exclusion | phecode |
| 681 | Superficial cellulitis and abscess | Dermatologic | 1.01 | 0.976 – 1.06 | 0.461 | 3017 | 19696 | exclusion | phecode |
| 681.1 | Cellulitis and abscess of fingers/toes | Dermatologic | 1.01 | 0.93 – 1.1 | 0.8 | 623 | 5888 | exclusion | phecode |
| 681.2 | Cellulitis and abscess of face/neck | Dermatologic | 1.1 | 0.999 – 1.21 | 0.0522 | 448 | 5093 | exclusion | phecode |
| 681.3 | Cellulitis and abscess of arm/hand | Dermatologic | 1.03 | 0.962 – 1.1 | 0.417 | 988 | 9841 | exclusion | phecode |
| 681.5 | Cellulitis and abscess of leg, except foot | Dermatologic | 1 | 0.938 – 1.07 | 0.981 | 1020 | 10279 | exclusion | phecode |
| 681.6 | Cellulitis and abscess of foot, toe | Dermatologic | 0.994 | 0.925 – 1.07 | 0.865 | 847 | 8341 | exclusion | phecode |
| 681.7 | Cellulitis and abscess of trunk | Dermatologic | 1.03 | 0.95 – 1.11 | 0.499 | 690 | 7781 | exclusion | phecode |
| 686 |
Other local infections of skin and subcutaneousOther local infections of skin and subcutaneous tissue
|
Dermatologic | 1.03 | 0.971 – 1.1 | 0.294 | 1082 | 10923 | exclusion | phecode |
| 686.1 | Carbuncle and furuncle | Dermatologic | 1.07 | 0.946 – 1.21 | 0.284 | 279 | 2997 | exclusion | phecode |
| 686.2 | Impetigo | Dermatologic | 1.02 | 0.892 – 1.18 | 0.74 | 222 | 2255 | exclusion | phecode |
| 686.3 | Pilonidal cyst | Dermatologic | 1.26 | 0.994 – 1.6 | 0.0561 | 78 | 896 | exclusion | phecode |
| 686.4 | Pyogenic granuloma | Dermatologic | 0.923 | 0.742 – 1.15 | 0.471 | 95 | 798 | exclusion | phecode |
| 686.5 | Pyoderma | Dermatologic | 1.04 | 0.747 – 1.45 | 0.811 | 33 | 322 | exclusion | phecode |
| 687 | Symptoms affecting skin | Dermatologic | 0.99 | 0.919 – 1.07 | 0.782 | 803 | 8074 | exclusion | phecode |
| 687.1 | Rash and other nonspecific skin eruption | Dermatologic | 1.01 | 0.97 – 1.04 | 0.747 | 3672 | 17603 | exclusion | phecode |
| 687.3 | Changes in skin texture | Dermatologic | 0.947 | 0.812 – 1.11 | 0.494 | 176 | 2071 | exclusion | phecode |
| 687.4 | Disturbance of skin sensation | Dermatologic | 0.989 | 0.951 – 1.03 | 0.57 | 3058 | 17286 | exclusion | phecode |
| 689 | Disorder of skin and subcutaneous tissue NOS | Dermatologic | 0.984 | 0.952 – 1.02 | 0.333 | 4842 | 18793 | exclusion | phecode |
| 690 | Erythematosquamous dermatosis | Dermatologic | 1.03 | 0.989 – 1.08 | 0.147 | 2730 | 15195 | exclusion | phecode |
| 690.1 | Seborrheic dermatitis | Dermatologic | 1.03 | 0.99 – 1.08 | 0.136 | 2727 | 15181 | exclusion | phecode |
| 691 | Congenital anomalies of skin | Dermatologic | 0.948 | 0.84 – 1.07 | 0.387 | 306 | 2766 | exclusion | phecode |
| 691.3 | Congenital pigmentary anomalies of skin | Dermatologic | 1.09 | 0.778 – 1.52 | 0.621 | 37 | 324 | exclusion | phecode |
| 694 | Dyschromia and Vitiligo | Dermatologic | 1 | 0.939 – 1.07 | 0.948 | 1058 | 8915 | exclusion | phecode |
| 694.1 | Vitiligo | Dermatologic | 1.1 | 0.86 – 1.4 | 0.457 | 70 | 681 | exclusion | phecode |
| 694.2 | Other dyschromia | Dermatologic | 1.01 | 0.939 – 1.08 | 0.873 | 964 | 8067 | exclusion | phecode |
| 694.3 | Vascular disorders of skin | Dermatologic | 0.823 | 0.597 – 1.13 | 0.234 | 37 | 386 | exclusion | phecode |
| 695 | Erythematous conditions | Dermatologic | 0.999 | 0.954 – 1.05 | 0.973 | 2131 | 14748 | exclusion | phecode |
| 695.1 | Toxic erythema | Dermatologic | 1 | 0.734 – 1.36 | 0.997 | 38 | 355 | exclusion | phecode |
| 695.2 | Bullous dermatoses | Dermatologic | 1.14 | 0.835 – 1.55 | 0.416 | 42 | 345 | exclusion | phecode |
| 695.3 | Rosacea | Dermatologic | 1.02 | 0.954 – 1.09 | 0.583 | 1028 | 8627 | exclusion | phecode |
| 695.4 | Lupus (localized and systemic) | Dermatologic | 1.02 | 0.912 – 1.15 | 0.697 | 326 | 3517 | exclusion | phecode |
| 695.41 | Cutaneous lupus erythematosus | Dermatologic | 1.1 | 0.905 – 1.33 | 0.345 | 120 | 1306 | exclusion | phecode |
| 695.42 | Systemic lupus erythematosus | Dermatologic | 1.03 | 0.913 – 1.16 | 0.657 | 311 | 3356 | exclusion | phecode |
| 695.7 | Prurigo and Lichen | Dermatologic | 1.13 | 0.998 – 1.28 | 0.0539 | 280 | 2917 | exclusion | phecode |
| 695.8 | Other specified erythematous conditions | Dermatologic | 1.01 | 0.907 – 1.12 | 0.88 | 402 | 3998 | exclusion | phecode |
| 695.81 | Erythema nodosum | Dermatologic | 0.845 | 0.593 – 1.2 | 0.353 | 34 | 277 | exclusion | phecode |
| 695.9 | Unspecified erythematous condition | Dermatologic | 0.911 | 0.81 – 1.02 | 0.118 | 318 | 3282 | exclusion | phecode |
| 696 | Psoriasis and related disorders | Dermatologic | 1.04 | 0.954 – 1.12 | 0.401 | 633 | 6794 | exclusion | phecode |
| 696.3 | Pityriasis | Dermatologic | 1.13 | 0.865 – 1.49 | 0.364 | 59 | 522 | exclusion | phecode |
| 696.4 | Psoriasis | Dermatologic | 1.04 | 0.95 – 1.13 | 0.426 | 572 | 6311 | exclusion | phecode |
| 696.41 | Psoriasis vulgaris | Dermatologic | 1 | 0.915 – 1.1 | 0.958 | 521 | 5786 | exclusion | phecode |
| 696.42 | Psoriatic arthropathy | Dermatologic | 1.24 | 1.04 – 1.49 | 0.018 | 127 | 1362 | exclusion | phecode |
| 697 | Sarcoidosis | Dermatologic | 1.05 | 0.9 – 1.22 | 0.541 | 191 | 1613 | exclusion | phecode |
| 698 | Pruritus and related conditions | Dermatologic | 1.03 | 0.973 – 1.1 | 0.286 | 1230 | 11315 | exclusion | phecode |
| 700 | Corns and callosities | Dermatologic | 1.11 | 1.03 – 1.2 | 0.0103 | 685 | 5395 | exclusion | phecode |
| 701 |
Other hypertrophic and atrophic conditions ofOther hypertrophic and atrophic conditions of skin
|
Dermatologic | 1.01 | 0.972 – 1.04 | 0.721 | 4065 | 19106 | exclusion | phecode |
| 701.1 | Keratoderma, acquired | Dermatologic | 1.09 | 0.962 – 1.23 | 0.176 | 271 | 2702 | exclusion | phecode |
| 701.2 | Scar conditions and fibrosis of skin | Dermatologic | 1.03 | 0.967 – 1.09 | 0.377 | 1177 | 10842 | exclusion | phecode |
| 701.3 | Circumscribed scleroderma | Dermatologic | 0.987 | 0.878 – 1.11 | 0.829 | 319 | 3001 | exclusion | phecode |
| 701.4 | Keloid scar | Dermatologic | 1.04 | 0.935 – 1.16 | 0.448 | 356 | 3074 | exclusion | phecode |
| 701.5 | Abnormal granulation tissue | Dermatologic | 1.01 | 0.869 – 1.17 | 0.903 | 196 | 2015 | exclusion | phecode |
| 702 |
Degenerative skin conditions and otherDegenerative skin conditions and other dermatoses
|
Dermatologic | 1.01 | 0.968 – 1.05 | 0.756 | 3563 | 14120 | exclusion | phecode |
| 702.1 | Actinic keratosis | Dermatologic | 1.01 | 0.964 – 1.06 | 0.664 | 2127 | 12227 | exclusion | phecode |
| 702.2 | Seborrheic keratosis | Dermatologic | 1.02 | 0.976 – 1.06 | 0.42 | 2825 | 15065 | exclusion | phecode |
| 702.4 | Degenerative skin disorders | Dermatologic | 1.07 | 0.77 – 1.49 | 0.685 | 38 | 422 | exclusion | phecode |
| 703 | Diseases of nail, NOS | Dermatologic | 1.11 | 1.04 – 1.2 | 0.00345 | 845 | 7367 | exclusion | phecode |
| 703.1 | Ingrowing nail | Dermatologic | 1.06 | 0.96 – 1.16 | 0.26 | 472 | 4477 | exclusion | phecode |
| 704 | Diseases of hair and hair follicles | Dermatologic | 1.02 | 0.974 – 1.08 | 0.351 | 1752 | 15315 | exclusion | phecode |
| 704.1 | Alopecia | Dermatologic | 1.02 | 0.949 – 1.1 | 0.576 | 813 | 7455 | exclusion | phecode |
| 704.11 | Alopecia Areata | Dermatologic | 0.846 | 0.601 – 1.19 | 0.34 | 34 | 436 | exclusion | phecode |
| 704.12 | Telogen effluvium | Dermatologic | 0.925 | 0.661 – 1.3 | 0.651 | 38 | 319 | exclusion | phecode |
| 704.2 | Hirsutism | Dermatologic | 1.11 | 0.949 – 1.3 | 0.189 | 171 | 1693 | exclusion | phecode |
| 704.8 |
Other specified diseases of hair and hairOther specified diseases of hair and hair follicles
|
Dermatologic | 1.01 | 0.941 – 1.08 | 0.836 | 951 | 8591 | exclusion | phecode |
| 705 | Disorders of sweat glands | Dermatologic | 1.05 | 0.93 – 1.2 | 0.406 | 266 | 3214 | exclusion | phecode |
| 705.1 | Dyshidrosis | Dermatologic | 0.914 | 0.727 – 1.15 | 0.44 | 79 | 800 | exclusion | phecode |
| 705.3 | Hidradenitis | Dermatologic | 1.15 | 0.913 – 1.45 | 0.235 | 77 | 1346 | exclusion | phecode |
| 705.8 | Hyperhidrosis | Dermatologic | 1.04 | 0.955 – 1.14 | 0.341 | 531 | 5612 | exclusion | phecode |
| 706 | Diseases of sebaceous glands | Dermatologic | 1.01 | 0.972 – 1.05 | 0.635 | 3280 | 19982 | exclusion | phecode |
| 706.1 | Acne | Dermatologic | 0.975 | 0.925 – 1.03 | 0.363 | 1583 | 12149 | exclusion | phecode |
| 706.2 | Sebaceous cyst | Dermatologic | 1.04 | 0.984 – 1.1 | 0.17 | 1457 | 13240 | exclusion | phecode |
| 706.3 | Seborrhea | Dermatologic | 1.24 | 0.866 – 1.79 | 0.238 | 34 | 282 | exclusion | phecode |
| 706.8 | Other specified diseases of sebaceous glands | Dermatologic | 1.04 | 0.963 – 1.11 | 0.347 | 817 | 7354 | exclusion | phecode |
| 707 | Chronic ulcer of skin | Dermatologic | 1.02 | 0.959 – 1.08 | 0.553 | 1219 | 12893 | exclusion | phecode |
| 707.1 | Decubitus ulcer | Dermatologic | 1.07 | 0.953 – 1.19 | 0.263 | 347 | 3777 | exclusion | phecode |
| 707.2 | Chronic ulcer of leg or foot | Dermatologic | 1.04 | 0.946 – 1.14 | 0.42 | 475 | 4775 | exclusion | phecode |
| 707.3 | Chronic ulcer of unspecified site | Dermatologic | 0.987 | 0.913 – 1.07 | 0.747 | 698 | 7938 | exclusion | phecode |
| 709 | Diffuse diseases of connective tissue | Dermatologic | 0.992 | 0.921 – 1.07 | 0.831 | 802 | 7427 | exclusion | phecode |
| 709.2 | Sicca syndrome | Dermatologic | 1.09 | 0.957 – 1.23 | 0.203 | 276 | 2553 | exclusion | phecode |
| 709.3 | Systemic sclerosis | Dermatologic | 1.02 | 0.844 – 1.24 | 0.809 | 113 | 1126 | exclusion | phecode |
| 709.5 | Dermatomyositis | Dermatologic | 0.981 | 0.735 – 1.31 | 0.896 | 49 | 453 | exclusion | phecode |
| 709.6 |
Other specified diffuse diseases of connectiveOther specified diffuse diseases of connective tissue
|
Dermatologic | 0.811 | 0.594 – 1.11 | 0.187 | 45 | 465 | exclusion | phecode |
| 709.7 | Unspecified diffuse connective tissue disease | Dermatologic | 0.957 | 0.871 – 1.05 | 0.354 | 512 | 4690 | exclusion | phecode |
| 710 |
Osteomyelitis, periostitis, and otherOsteomyelitis, periostitis, and other infections involving bone
|
Musculoskeletal | 1.06 | 0.97 – 1.16 | 0.191 | 519 | 5950 | exclusion | phecode |
| 710.1 | Osteomyelitis | Musculoskeletal | 1.07 | 0.971 – 1.17 | 0.183 | 490 | 5710 | exclusion | phecode |
| 710.11 | Acute osteomyelitis | Musculoskeletal | 1.18 | 1.03 – 1.35 | 0.0191 | 229 | 2817 | exclusion | phecode |
| 710.12 | Chronic osteomyelitis | Musculoskeletal | 1.12 | 0.979 – 1.29 | 0.0964 | 221 | 2528 | exclusion | phecode |
| 710.19 | Unspecified osteomyelitis | Musculoskeletal | 1.06 | 0.965 – 1.17 | 0.22 | 472 | 5458 | exclusion | phecode |
| 711 | Arthropathy associated with infections | Musculoskeletal | 1 | 0.86 – 1.17 | 0.982 | 183 | 2030 | exclusion | phecode |
| 711.1 | Pyogenic arthritis | Musculoskeletal | 0.913 | 0.762 – 1.09 | 0.326 | 126 | 1408 | exclusion | phecode |
| 712 | Infective connective tissue disorders | Musculoskeletal | 1.06 | 0.837 – 1.35 | 0.612 | 68 | 843 | exclusion | phecode |
| 713 |
Arthropathy associated with other disordersArthropathy associated with other disorders classified elsewhere
|
Musculoskeletal | 1.02 | 0.87 – 1.2 | 0.793 | 158 | 1606 | exclusion | phecode |
| 713.5 |
Arthropathy associated with neurologicalArthropathy associated with neurological disorders
|
Musculoskeletal | 1.07 | 0.873 – 1.3 | 0.53 | 97 | 927 | exclusion | phecode |
| 714 |
Rheumatoid arthritis and other inflammatoryRheumatoid arthritis and other inflammatory polyarthropathies
|
Musculoskeletal | 1.01 | 0.946 – 1.08 | 0.737 | 963 | 9371 | exclusion | phecode |
| 714.1 | Rheumatoid arthritis | Musculoskeletal | 1.01 | 0.936 – 1.09 | 0.822 | 762 | 7774 | exclusion | phecode |
| 714.2 | Juvenile rheumatoid arthritis | Musculoskeletal | 1.02 | 0.765 – 1.36 | 0.899 | 47 | 488 | exclusion | phecode |
| 715 | Other inflammatory spondylopathies | Musculoskeletal | 1.05 | 0.961 – 1.15 | 0.286 | 547 | 5994 | exclusion | phecode |
| 715.1 | Sacroiliitis NEC | Musculoskeletal | 0.894 | 0.747 – 1.07 | 0.22 | 129 | 1342 | exclusion | phecode |
| 715.2 | Ankylosing spondylitis | Musculoskeletal | 1.03 | 0.854 – 1.25 | 0.732 | 111 | 1115 | exclusion | phecode |
| 716 | Other arthropathies | Musculoskeletal | 1.01 | 0.977 – 1.04 | 0.637 | 6166 | 16556 | exclusion | phecode |
| 716.1 | Unspecified polyarthropathy or polyarthritis | Musculoskeletal | 0.938 | 0.758 – 1.16 | 0.552 | 96 | 990 | exclusion | phecode |
| 716.2 | Unspecified monoarthritis | Musculoskeletal | 0.728 | 0.552 – 0.961 | 0.0249 | 62 | 625 | exclusion | phecode |
| 716.9 | Arthropathy NOS | Musculoskeletal | 1.01 | 0.976 – 1.04 | 0.652 | 6130 | 16549 | exclusion | phecode |
| 717 | Polymyalgia Rheumatica | Musculoskeletal | 0.969 | 0.795 – 1.18 | 0.758 | 107 | 1208 | exclusion | phecode |
| 720 | Spinal stenosis | Musculoskeletal | 0.963 | 0.914 – 1.01 | 0.157 | 1648 | 13933 | exclusion | phecode |
| 720.1 | Spinal stenosis of lumbar region | Musculoskeletal | 0.97 | 0.913 – 1.03 | 0.323 | 1191 | 11278 | exclusion | phecode |
| 721 | Spondylosis and allied disorders | Musculoskeletal | 0.982 | 0.94 – 1.03 | 0.426 | 2397 | 16190 | exclusion | phecode |
| 721.1 | Spondylosis without myelopathy | Musculoskeletal | 0.978 | 0.935 – 1.02 | 0.335 | 2241 | 15889 | exclusion | phecode |
| 721.2 | Spondylosis with myelopathy | Musculoskeletal | 1.09 | 0.98 – 1.22 | 0.111 | 364 | 4144 | exclusion | phecode |
| 721.8 | Other allied disorders of spine | Musculoskeletal | 0.962 | 0.805 – 1.15 | 0.668 | 126 | 1302 | exclusion | phecode |
| 722 | Intervertebral disc disorders | Musculoskeletal | 0.981 | 0.941 – 1.02 | 0.346 | 2785 | 17446 | exclusion | phecode |
| 722.1 | Displacement of intervertebral disc | Musculoskeletal | 0.969 | 0.92 – 1.02 | 0.241 | 1619 | 15854 | exclusion | phecode |
| 722.3 | Schmorl's nodes | Musculoskeletal | 0.916 | 0.702 – 1.19 | 0.515 | 59 | 595 | exclusion | phecode |
| 722.6 | Degeneration of intervertebral disc | Musculoskeletal | 0.972 | 0.924 – 1.02 | 0.272 | 1715 | 15213 | exclusion | phecode |
| 722.7 | Intervertebral disc disorder with myelopathy | Musculoskeletal | 0.88 | 0.767 – 1.01 | 0.0684 | 214 | 2548 | exclusion | phecode |
| 722.8 | Postlaminectomy syndrome | Musculoskeletal | 1.01 | 0.859 – 1.18 | 0.919 | 161 | 1963 | exclusion | phecode |
| 722.9 | Other and unspecified disc disorder | Musculoskeletal | 1.02 | 0.946 – 1.09 | 0.659 | 831 | 9665 | exclusion | phecode |
| 723 | Other disorders of cervical region | Musculoskeletal | 1.01 | 0.915 – 1.11 | 0.881 | 465 | 4801 | exclusion | phecode |
| 723.1 | Torticollis | Musculoskeletal | 1.07 | 0.897 – 1.29 | 0.437 | 132 | 1281 | exclusion | phecode |
| 724 | Other and unspecified disorders of back | Musculoskeletal | 0.966 | 0.921 – 1.01 | 0.152 | 1971 | 16362 | exclusion | phecode |
| 724.1 | Disorders of sacrum | Musculoskeletal | 0.963 | 0.904 – 1.02 | 0.234 | 1110 | 11402 | exclusion | phecode |
| 724.2 | Disorders of coccyx | Musculoskeletal | 1.02 | 0.889 – 1.17 | 0.784 | 223 | 2272 | exclusion | phecode |
| 724.8 | Other symptoms referable to back | Musculoskeletal | 0.947 | 0.858 – 1.04 | 0.277 | 439 | 4824 | exclusion | phecode |
| 724.9 | Other unspecified back disorders | Musculoskeletal | 1.02 | 0.942 – 1.11 | 0.589 | 617 | 6988 | exclusion | phecode |
| 726 | Peripheral enthesopathies and allied syndromes | Musculoskeletal | 0.999 | 0.967 – 1.03 | 0.935 | 5347 | 15013 | exclusion | phecode |
| 726.1 | Enthesopathy | Musculoskeletal | 0.999 | 0.964 – 1.03 | 0.946 | 4084 | 14966 | exclusion | phecode |
| 726.2 | Synoviopathy | Musculoskeletal | 1.08 | 0.982 – 1.18 | 0.118 | 533 | 4799 | exclusion | phecode |
| 726.3 | Bursitis | Musculoskeletal | 1.05 | 0.983 – 1.12 | 0.15 | 1033 | 8083 | exclusion | phecode |
| 726.4 | Calcaneal spur; Exostosis NOS | Musculoskeletal | 1.03 | 0.952 – 1.12 | 0.44 | 659 | 5662 | exclusion | phecode |
| 727 | Other disorders of synovium, tendon, and bursa | Musculoskeletal | 1.01 | 0.971 – 1.04 | 0.716 | 3915 | 14966 | exclusion | phecode |
| 727.1 | Synovitis and tenosynovitis | Musculoskeletal | 1.01 | 0.954 – 1.06 | 0.829 | 1660 | 12427 | exclusion | phecode |
| 727.2 | Bursitis disorders | Musculoskeletal | 1.02 | 0.879 – 1.18 | 0.824 | 214 | 1974 | exclusion | phecode |
| 727.4 | Ganglion and cyst of synovium, tendon, and bursa | Musculoskeletal | 1 | 0.928 – 1.08 | 0.958 | 748 | 6792 | exclusion | phecode |
| 727.5 | Rupture of synovium | Musculoskeletal | 0.998 | 0.873 – 1.14 | 0.975 | 246 | 2271 | exclusion | phecode |
| 727.6 | Rupture of tendon, nontraumatic | Musculoskeletal | 1.03 | 0.969 – 1.09 | 0.348 | 1231 | 10160 | exclusion | phecode |
| 727.7 | Contracture of tendon (sheath) | Musculoskeletal | 0.946 | 0.839 – 1.07 | 0.362 | 299 | 2974 | exclusion | phecode |
| 727.8 | Plica syndrome | Musculoskeletal | 1.21 | 0.972 – 1.5 | 0.0895 | 90 | 735 | exclusion | phecode |
| 728 | Disorders of muscle, ligament, and fascia | Musculoskeletal | 0.989 | 0.945 – 1.04 | 0.65 | 2184 | 14499 | exclusion | phecode |
| 728.1 | Muscular calcification and ossification | Musculoskeletal | 1.02 | 0.748 – 1.4 | 0.891 | 42 | 411 | exclusion | phecode |
| 728.2 | Laxity of ligament or hypermobility syndrome | Musculoskeletal | 0.968 | 0.813 – 1.15 | 0.716 | 137 | 1493 | exclusion | phecode |
| 728.7 | Fasciitis | Musculoskeletal | 0.987 | 0.935 – 1.04 | 0.638 | 1553 | 11342 | exclusion | phecode |
| 728.71 |
Contracture of palmar fascia [Dupuytren'sContracture of palmar fascia [Dupuytren's disease]
|
Musculoskeletal | 0.995 | 0.855 – 1.16 | 0.949 | 187 | 1852 | exclusion | phecode |
| 729 | Other disorders of soft tissues | Musculoskeletal | 0.993 | 0.943 – 1.04 | 0.775 | 1703 | 13192 | exclusion | phecode |
| 729.1 | Rheumatism, unspecified and fibrositis | Musculoskeletal | 0.989 | 0.696 – 1.4 | 0.951 | 31 | 369 | exclusion | phecode |
| 729.3 | Panniculitis | Musculoskeletal | 0.831 | 0.637 – 1.08 | 0.172 | 63 | 566 | exclusion | phecode |
| 729.7 | Nontraumatic compartment syndrome | Musculoskeletal | 1.22 | 0.801 – 1.85 | 0.359 | 23 | 300 | exclusion | phecode |
| 731 |
Osteitis deformans and osteopathies associatedOsteitis deformans and osteopathies associated with other disorders classified elsewhere
|
Musculoskeletal | 1.02 | 0.819 – 1.26 | 0.888 | 98 | 980 | exclusion | phecode |
| 732 | Osteochondropathies | Musculoskeletal | 0.891 | 0.772 – 1.03 | 0.117 | 203 | 2035 | exclusion | phecode |
| 732.1 | Juvenile osteochondrosis | Musculoskeletal | 0.873 | 0.712 – 1.07 | 0.193 | 110 | 1077 | exclusion | phecode |
| 732.7 | Osteochondritis dissecans | Musculoskeletal | 0.871 | 0.645 – 1.18 | 0.37 | 47 | 493 | exclusion | phecode |
| 733 | Other disorders of bone and cartilage | Musculoskeletal | 0.992 | 0.949 – 1.04 | 0.724 | 2440 | 13423 | exclusion | phecode |
| 733.2 | Cyst of bone | Musculoskeletal | 0.815 | 0.659 – 1.01 | 0.0585 | 99 | 1010 | exclusion | phecode |
| 733.4 | Aseptic necrosis of bone | Musculoskeletal | 1.04 | 0.902 – 1.21 | 0.565 | 202 | 2482 | exclusion | phecode |
| 733.6 | Costochondritis | Musculoskeletal | 1.04 | 0.902 – 1.2 | 0.571 | 194 | 1875 | exclusion | phecode |
| 733.8 | Malunion and nonunion of fracture | Musculoskeletal | 0.996 | 0.895 – 1.11 | 0.935 | 368 | 4197 | exclusion | phecode |
| 733.9 | Chondromalacia | Musculoskeletal | 0.853 | 0.644 – 1.13 | 0.266 | 59 | 534 | exclusion | phecode |
| 735 | Acquired foot deformities | Musculoskeletal | 1.04 | 0.991 – 1.09 | 0.11 | 1851 | 14704 | exclusion | phecode |
| 735.1 | Flat foot | Musculoskeletal | 0.963 | 0.86 – 1.08 | 0.51 | 358 | 3089 | exclusion | phecode |
| 735.2 | Acquired toe deformities | Musculoskeletal | 1.11 | 1.03 – 1.2 | 0.00945 | 712 | 5978 | exclusion | phecode |
| 735.21 | Hammer toe (acquired) | Musculoskeletal | 1.17 | 1.05 – 1.29 | 0.00272 | 430 | 3742 | exclusion | phecode |
| 735.23 | Hallux rigidus | Musculoskeletal | 1 | 0.865 – 1.16 | 0.998 | 222 | 1991 | exclusion | phecode |
| 735.3 | Hallux valgus (Bunion) | Musculoskeletal | 1.04 | 0.972 – 1.12 | 0.238 | 846 | 7326 | exclusion | phecode |
| 736 | Other acquired deformities of limbs | Musculoskeletal | 1.01 | 0.957 – 1.07 | 0.718 | 1500 | 13266 | exclusion | phecode |
| 736.1 | Acquired deformities of forearm | Musculoskeletal | 1.15 | 0.857 – 1.54 | 0.353 | 53 | 496 | exclusion | phecode |
| 736.2 | Acquired deformities of finger | Musculoskeletal | 1.04 | 0.863 – 1.26 | 0.662 | 123 | 1126 | exclusion | phecode |
| 736.3 | Acquired deformities of hip | Musculoskeletal | 1.2 | 0.845 – 1.7 | 0.308 | 36 | 317 | exclusion | phecode |
| 736.4 | Genu valgum or varum (acquired) | Musculoskeletal | 0.972 | 0.829 – 1.14 | 0.727 | 179 | 1566 | exclusion | phecode |
| 736.5 | Acquired deformities of knee | Musculoskeletal | 0.985 | 0.818 – 1.19 | 0.875 | 127 | 1149 | exclusion | phecode |
| 736.6 | Unequal leg length (acquired) | Musculoskeletal | 1.08 | 0.932 – 1.26 | 0.296 | 186 | 1739 | exclusion | phecode |
| 737 | Curvature of spine | Musculoskeletal | 1.03 | 0.956 – 1.11 | 0.436 | 787 | 8038 | exclusion | phecode |
| 737.1 | Kyphosis (acquired) | Musculoskeletal | 1.05 | 0.914 – 1.21 | 0.487 | 225 | 2415 | exclusion | phecode |
| 737.2 | Lordosis (acquired) | Musculoskeletal | 0.96 | 0.678 – 1.36 | 0.819 | 32 | 362 | exclusion | phecode |
| 737.3 | Kyphoscoliosis and scoliosis | Musculoskeletal | 1.05 | 0.967 – 1.15 | 0.234 | 605 | 6210 | exclusion | phecode |
| 738 | Other acquired musculoskeletal deformity | Musculoskeletal | 0.981 | 0.923 – 1.04 | 0.547 | 1145 | 12094 | exclusion | phecode |
| 738.4 | Acquired spondylolisthesis | Musculoskeletal | 1.02 | 0.924 – 1.12 | 0.745 | 461 | 5042 | exclusion | phecode |
| 739 | Contracture of joint | Musculoskeletal | 0.938 | 0.836 – 1.05 | 0.28 | 328 | 3191 | exclusion | phecode |
| 740 | Osteoarthrosis | Musculoskeletal | 0.992 | 0.963 – 1.02 | 0.582 | 7462 | 16020 | exclusion | phecode |
| 740.1 | Osteoarthritis; localized | Musculoskeletal | 1.01 | 0.97 – 1.05 | 0.683 | 3495 | 13989 | exclusion | phecode |
| 740.11 | Osteoarthrosis, localized, primary | Musculoskeletal | 1.01 | 0.967 – 1.05 | 0.723 | 3090 | 13238 | exclusion | phecode |
| 740.12 | Osteoarthrosis, localized, secondary | Musculoskeletal | 0.96 | 0.865 – 1.07 | 0.449 | 392 | 3525 | exclusion | phecode |
| 740.2 | Osteoarthrosis, generalized | Musculoskeletal | 1.01 | 0.938 – 1.09 | 0.747 | 765 | 5908 | exclusion | phecode |
| 740.3 |
Osteoarthrosis involving more than one siteOsteoarthrosis involving more than one site, but not specified as generalized
|
Musculoskeletal | 1.04 | 0.889 – 1.21 | 0.646 | 172 | 1806 | exclusion | phecode |
| 740.9 | Osteoarthrosis NOS | Musculoskeletal | 0.989 | 0.959 – 1.02 | 0.479 | 7112 | 15917 | exclusion | phecode |
| 741 | Symptoms and disorders of the joints | Musculoskeletal | 1.01 | 0.973 – 1.04 | 0.727 | 4458 | 17992 | exclusion | phecode |
| 741.1 | Ankylosis of joint | Musculoskeletal | 0.956 | 0.803 – 1.14 | 0.61 | 139 | 1239 | exclusion | phecode |
| 741.2 | Stiffness of joint | Musculoskeletal | 1 | 0.925 – 1.09 | 0.958 | 696 | 6260 | exclusion | phecode |
| 741.3 | Difficulty in walking | Musculoskeletal | 1.01 | 0.953 – 1.08 | 0.671 | 1167 | 10908 | exclusion | phecode |
| 741.4 | Joint effusions | Musculoskeletal | 1.02 | 0.968 – 1.08 | 0.414 | 1387 | 12288 | exclusion | phecode |
| 741.5 | Hemarthrosis | Musculoskeletal | 0.991 | 0.735 – 1.34 | 0.955 | 43 | 490 | exclusion | phecode |
| 741.6 | Villonodular synovitis | Musculoskeletal | 1.23 | 0.878 – 1.72 | 0.23 | 36 | 382 | exclusion | phecode |
| 742 | Derangement of joint, non-traumatic | Musculoskeletal | 1.01 | 0.964 – 1.05 | 0.749 | 2405 | 17143 | exclusion | phecode |
| 742.1 | Loose body in joint | Musculoskeletal | 1.08 | 0.868 – 1.35 | 0.484 | 96 | 821 | exclusion | phecode |
| 742.2 |
Pathological, developmental or recurrentPathological, developmental or recurrent dislocation
|
Musculoskeletal | 1.11 | 0.942 – 1.3 | 0.216 | 168 | 1614 | exclusion | phecode |
| 742.8 | Articular cartilage disorder | Musculoskeletal | 0.907 | 0.761 – 1.08 | 0.277 | 149 | 1300 | exclusion | phecode |
| 742.9 | Other derangement of joint | Musculoskeletal | 0.999 | 0.955 – 1.04 | 0.95 | 2237 | 16822 | exclusion | phecode |
| 743 |
Osteoporosis, osteopenia and pathologicalOsteoporosis, osteopenia and pathological fracture
|
Musculoskeletal | 0.969 | 0.936 – 1 | 0.0696 | 4607 | 18691 | exclusion | phecode |
| 743.1 | Osteoporosis | Musculoskeletal | 0.947 | 0.898 – 0.998 | 0.0432 | 1794 | 9509 | exclusion | phecode |
| 743.11 | Osteoporosis NOS | Musculoskeletal | 0.954 | 0.905 – 1.01 | 0.0873 | 1765 | 9431 | exclusion | phecode |
| 743.12 | Senile osteoporosis | Musculoskeletal | 0.923 | 0.827 – 1.03 | 0.153 | 374 | 2975 | exclusion | phecode |
| 743.13 | Other specified osteoporosis | Musculoskeletal | 0.875 | 0.746 – 1.03 | 0.101 | 177 | 1573 | exclusion | phecode |
| 743.2 | Pathologic fracture | Musculoskeletal | 0.895 | 0.817 – 0.981 | 0.0176 | 532 | 5174 | exclusion | phecode |
| 743.21 | Pathologic fracture of vertebrae | Musculoskeletal | 0.916 | 0.79 – 1.06 | 0.245 | 197 | 2212 | exclusion | phecode |
| 743.22 | Pathologic fracture of femur | Musculoskeletal | 0.919 | 0.719 – 1.18 | 0.502 | 75 | 685 | exclusion | phecode |
| 743.4 | Stress fracture | Musculoskeletal | 0.906 | 0.787 – 1.04 | 0.17 | 231 | 2163 | exclusion | phecode |
| 743.9 |
Osteopenia or other disorder of bone andOsteopenia or other disorder of bone and cartilage
|
Musculoskeletal | 0.975 | 0.939 – 1.01 | 0.197 | 3543 | 17656 | exclusion | phecode |
| 745 | Pain in joint | Musculoskeletal | 0.995 | 0.97 – 1.02 | 0.723 | 10551 | 13181 | exclusion | phecode |
| 747 | Cardiac and circulatory congenital anomalies | Congenital Anomalies | 0.94 | 0.881 – 1 | 0.0609 | 1053 | 10955 | exclusion | phecode |
| 747.1 | Cardiac congenital anomalies | Congenital Anomalies | 0.912 | 0.847 – 0.981 | 0.0136 | 824 | 8633 | exclusion | phecode |
| 747.11 | Cardiac shunt/ heart septal defect | Congenital Anomalies | 0.967 | 0.859 – 1.09 | 0.577 | 317 | 3279 | exclusion | phecode |
| 747.12 | Valvular heart disease/ heart chambers | Congenital Anomalies | 0.954 | 0.851 – 1.07 | 0.415 | 328 | 3481 | exclusion | phecode |
| 747.13 | Congenital anomalies of great vessels | Congenital Anomalies | 0.874 | 0.755 – 1.01 | 0.0719 | 195 | 1966 | exclusion | phecode |
| 747.2 |
Congenital anomalies of peripheral vascularCongenital anomalies of peripheral vascular system
|
Congenital Anomalies | 0.969 | 0.849 – 1.1 | 0.635 | 249 | 2547 | exclusion | phecode |
| 748 | Anomalies of respiratory system, congenital | Congenital Anomalies | 1.09 | 0.817 – 1.46 | 0.547 | 50 | 552 | exclusion | phecode |
| 749 | Congenital anomalies of face and neck | Congenital Anomalies | 0.975 | 0.867 – 1.1 | 0.666 | 316 | 3058 | exclusion | phecode |
| 749.1 | Cleft palate | Congenital Anomalies | 1.12 | 0.855 – 1.48 | 0.405 | 57 | 568 | exclusion | phecode |
| 749.2 | Congenital anomalies of skull and face bones | Congenital Anomalies | 0.912 | 0.713 – 1.17 | 0.464 | 68 | 609 | exclusion | phecode |
| 750 | Digestive congenital anomalies | Congenital Anomalies | 0.902 | 0.819 – 0.994 | 0.0379 | 456 | 4575 | exclusion | phecode |
| 750.1 | Upper gastrointestinal congenital anomalies | Congenital Anomalies | 0.869 | 0.748 – 1.01 | 0.0673 | 185 | 1824 | exclusion | phecode |
| 750.11 | Esophageal atresia/tracheoesophageal fistula | Congenital Anomalies | 0.764 | 0.591 – 0.987 | 0.0397 | 60 | 562 | exclusion | phecode |
| 750.13 | Congenital anomalies of mouth/tongue | Congenital Anomalies | 0.9 | 0.69 – 1.17 | 0.434 | 57 | 531 | exclusion | phecode |
| 750.14 | Congenital anomalies of esophagus | Congenital Anomalies | 0.891 | 0.688 – 1.15 | 0.379 | 63 | 633 | exclusion | phecode |
| 750.15 | Congenital anomalies of stomach | Congenital Anomalies | 0.752 | 0.523 – 1.08 | 0.125 | 30 | 297 | exclusion | phecode |
| 750.2 | Lower gastrointestinal congenital anomalies | Congenital Anomalies | 0.906 | 0.799 – 1.03 | 0.119 | 271 | 2747 | exclusion | phecode |
| 750.21 | Congenital anomalies of intestine | Congenital Anomalies | 0.911 | 0.776 – 1.07 | 0.253 | 165 | 1602 | exclusion | phecode |
| 750.22 |
Congenital anomaly of gallbladder, bile ductsCongenital anomaly of gallbladder, bile ducts, liver, pancreas
|
Congenital Anomalies | 0.941 | 0.779 – 1.14 | 0.53 | 109 | 1136 | exclusion | phecode |
| 751 | Genitourinary congenital anomalies | Congenital Anomalies | 0.933 | 0.874 – 0.996 | 0.0388 | 1001 | 9990 | exclusion | phecode |
| 751.1 | Congenital anomalies of genital organs | Congenital Anomalies | 0.812 | 0.722 – 0.914 | 0.000552 | 316 | 3121 | exclusion | phecode |
| 751.11 | Congenital anomalies of female genital organs | Congenital Anomalies | 0.828 | 0.719 – 0.953 | 0.00872 | 220 | 2176 | exclusion | phecode |
| 751.12 | Congenital anomalies of male genital organs | Congenital Anomalies | 0.863 | 0.673 – 1.11 | 0.242 | 74 | 767 | exclusion | phecode |
| 751.2 | Congenital anomalies of urinary system | Congenital Anomalies | 1.01 | 0.934 – 1.1 | 0.762 | 653 | 6607 | exclusion | phecode |
| 751.21 | Cystic kidney disease | Congenital Anomalies | 0.982 | 0.892 – 1.08 | 0.704 | 463 | 4631 | exclusion | phecode |
| 751.22 | Other specified congenital anomalies of kidney | Congenital Anomalies | 1.11 | 0.932 – 1.33 | 0.236 | 131 | 1451 | exclusion | phecode |
| 751.3 | Obstructive genitourinary defect | Congenital Anomalies | 1.03 | 0.836 – 1.26 | 0.802 | 102 | 978 | exclusion | phecode |
| 752 | Nervous system congenital anomalies | Congenital Anomalies | 1.03 | 0.94 – 1.13 | 0.546 | 526 | 5702 | exclusion | phecode |
| 752.1 | Neural tube defects | Congenital Anomalies | 1.03 | 0.935 – 1.14 | 0.515 | 415 | 4580 | exclusion | phecode |
| 752.11 | Spina bifida | Congenital Anomalies | 0.991 | 0.803 – 1.22 | 0.936 | 98 | 953 | exclusion | phecode |
| 752.2 |
Other specified congenital anomalies of nervousOther specified congenital anomalies of nervous system
|
Congenital Anomalies | 0.987 | 0.82 – 1.19 | 0.894 | 128 | 1238 | exclusion | phecode |
| 753 | Congenital anomalies of the eye | Congenital Anomalies | 1.23 | 0.999 – 1.52 | 0.0506 | 107 | 1096 | exclusion | phecode |
| 753.1 | Congenital cataract and lens anomalies | Congenital Anomalies | 1.48 | 1.01 – 2.18 | 0.046 | 34 | 320 | exclusion | phecode |
| 753.2 | Congenital anomalies of posterior segment of eye | Congenital Anomalies | 1.12 | 0.764 – 1.63 | 0.566 | 30 | 309 | exclusion | phecode |
| 754 | Congenital musculoskeletal deformities of spine | Congenital Anomalies | 1.01 | 0.925 – 1.11 | 0.806 | 527 | 5935 | exclusion | phecode |
| 754.1 | Lumbosacral spondylolysis, congenital | Congenital Anomalies | 1.08 | 0.815 – 1.43 | 0.592 | 59 | 673 | exclusion | phecode |
| 754.2 | Spondylolisthesis, congenital | Congenital Anomalies | 1.02 | 0.894 – 1.16 | 0.786 | 241 | 2725 | exclusion | phecode |
| 755 | Congenital anomalies of limbs | Congenital Anomalies | 1.02 | 0.921 – 1.12 | 0.725 | 439 | 4081 | exclusion | phecode |
| 755.1 | Congenital deformities of feet | Congenital Anomalies | 1.04 | 0.903 – 1.21 | 0.562 | 213 | 1918 | exclusion | phecode |
| 755.4 |
Congenital anomalies of upper limb, includingCongenital anomalies of upper limb, including shoulder girdle
|
Congenital Anomalies | 0.847 | 0.627 – 1.14 | 0.277 | 39 | 404 | exclusion | phecode |
| 755.6 |
Other congenital anomalies of lower limbOther congenital anomalies of lower limb, including pelvic girdle
|
Congenital Anomalies | 1.02 | 0.88 – 1.18 | 0.814 | 200 | 1882 | exclusion | phecode |
| 755.61 | Congenital hip dysplasia and deformity | Congenital Anomalies | 1.09 | 0.902 – 1.31 | 0.377 | 116 | 1058 | exclusion | phecode |
| 756 | Other congenital musculoskeletal anomalies | Congenital Anomalies | 0.977 | 0.905 – 1.06 | 0.562 | 723 | 7025 | exclusion | phecode |
| 756.1 | Congenital anomalies of abdominal wall; diaphram | Congenital Anomalies | 0.942 | 0.685 – 1.3 | 0.712 | 37 | 371 | exclusion | phecode |
| 756.2 |
Pectus and other congenital anomalies ofPectus and other congenital anomalies of ribs/sternum
|
Congenital Anomalies | 0.701 | 0.515 – 0.955 | 0.0241 | 52 | 429 | exclusion | phecode |
| 756.3 |
Congenital anomalies of muscle, tendon, fasciaCongenital anomalies of muscle, tendon, fascia, and connective tissue
|
Congenital Anomalies | 1.03 | 0.884 – 1.2 | 0.691 | 182 | 1713 | exclusion | phecode |
| 756.5 | Congenital osteodystrophies | Congenital Anomalies | 0.996 | 0.909 – 1.09 | 0.933 | 512 | 5022 | exclusion | phecode |
| 757 | Congenital anomalies of the integument | Congenital Anomalies | 1 | 0.873 – 1.15 | 0.981 | 226 | 1939 | exclusion | phecode |
| 758 | Chromosomal anomalies and genetic disorders | Congenital Anomalies | 0.86 | 0.71 – 1.04 | 0.123 | 117 | 985 | exclusion | phecode |
| 758.1 | Chromosomal anomalies | Congenital Anomalies | 0.941 | 0.76 – 1.17 | 0.58 | 87 | 737 | exclusion | phecode |
| 759 | Other and unspecified congenital anomalies | Congenital Anomalies | 0.957 | 0.854 – 1.07 | 0.444 | 331 | 2852 | exclusion | phecode |
| 759.1 | Anomalies of endocrine glands, congenital | Congenital Anomalies | 0.901 | 0.667 – 1.22 | 0.501 | 45 | 389 | exclusion | phecode |
| 760 | Back pain | Symptoms | 0.996 | 0.969 – 1.02 | 0.78 | 7680 | 16043 | exclusion | phecode |
| 761 | Cervicalgia | Symptoms | 1.02 | 0.979 – 1.06 | 0.386 | 3152 | 20232 | exclusion | phecode |
| 763 |
Thoracic or lumbosacral neuritis orThoracic or lumbosacral neuritis or radiculitis, unspecified
|
Symptoms | 0.994 | 0.944 – 1.05 | 0.825 | 1651 | 16148 | exclusion | phecode |
| 764 | Sciatica | Symptoms | 0.99 | 0.939 – 1.04 | 0.719 | 1547 | 15988 | exclusion | phecode |
| 765 | Cervical radiculitis | Symptoms | 1.03 | 0.963 – 1.11 | 0.352 | 839 | 8976 | exclusion | phecode |
| 766 | Neuralgia, neuritis, and radiculitis NOS | Symptoms | 0.993 | 0.951 – 1.04 | 0.769 | 2371 | 18781 | exclusion | phecode |
| 767 | Cervicocranial/Cervicobrachial syndrome | Symptoms | 1.1 | 0.838 – 1.44 | 0.495 | 58 | 598 | exclusion | phecode |
| 769 | Nonallopathic lesions NEC | Symptoms | 0.978 | 0.897 – 1.07 | 0.623 | 574 | 5808 | exclusion | phecode |
| 770 | Myalgia and myositis unspecified | Symptoms | 0.993 | 0.953 – 1.04 | 0.757 | 2698 | 17699 | exclusion | phecode |
| 771 | Musculoskeletal symptoms referable to limbs | Symptoms | 0.977 | 0.935 – 1.02 | 0.292 | 2347 | 17917 | exclusion | phecode |
| 771.1 | Swelling of limb | Symptoms | 0.988 | 0.948 – 1.03 | 0.57 | 2687 | 17888 | exclusion | phecode |
| 771.2 | Cramp of limb | Symptoms | 1.05 | 0.957 – 1.15 | 0.314 | 532 | 5185 | exclusion | phecode |
| 772 | Symptoms of the muscles | Symptoms | 1.03 | 0.967 – 1.1 | 0.359 | 1127 | 10193 | exclusion | phecode |
| 772.1 | Muscular wasting and disuse atrophy | Symptoms | 1.03 | 0.896 – 1.19 | 0.665 | 227 | 2202 | exclusion | phecode |
| 772.2 | Spasm of muscle | Symptoms | 0.957 | 0.899 – 1.02 | 0.16 | 1145 | 11746 | exclusion | phecode |
| 772.3 | Muscle weakness | Symptoms | 0.987 | 0.933 – 1.04 | 0.655 | 1363 | 13579 | exclusion | phecode |
| 772.4 | Rhabdomyolysis | Symptoms | 0.951 | 0.743 – 1.22 | 0.688 | 64 | 754 | exclusion | phecode |
| 772.6 | Facial weakness | Symptoms | 1.06 | 0.926 – 1.22 | 0.385 | 233 | 2218 | exclusion | phecode |
| 780 | Hypothermia/Chills | Symptoms | 1.09 | 0.953 – 1.26 | 0.201 | 229 | 2226 | exclusion | phecode |
| 781 |
Symptoms involving nervous and musculoskeletalSymptoms involving nervous and musculoskeletal systems
|
Symptoms | 0.986 | 0.931 – 1.04 | 0.635 | 1319 | 12702 | exclusion | phecode |
| 781.1 | Loss of height | Symptoms | 0.848 | 0.652 – 1.1 | 0.22 | 59 | 591 | exclusion | phecode |
| 781.2 | Abnormal posture | Symptoms | 0.996 | 0.718 – 1.38 | 0.983 | 34 | 270 | exclusion | phecode |
| 782.3 | Edema | Symptoms | 1.03 | 0.985 – 1.07 | 0.208 | 2759 | 18189 | exclusion | phecode |
| 782.6 | Pallor and flushing | Symptoms | 0.969 | 0.883 – 1.06 | 0.51 | 522 | 4766 | exclusion | phecode |
| 783 | Fever of unknown origin | Symptoms | 0.996 | 0.957 – 1.04 | 0.862 | 2783 | 20756 | exclusion | phecode |
| 783.1 | Postprocedural fever | Symptoms | 1.07 | 0.893 – 1.29 | 0.458 | 131 | 1463 | exclusion | phecode |
| 785 | Abdominal pain | Symptoms | 1.01 | 0.979 – 1.03 | 0.677 | 8155 | 15575 | exclusion | phecode |
| 788 | Syncope and collapse | Symptoms | 1.02 | 0.967 – 1.06 | 0.543 | 1898 | 17805 | exclusion | phecode |
| 789 | Nausea and vomiting | Symptoms | 0.974 | 0.944 – 1.01 | 0.105 | 5327 | 18348 | exclusion | phecode |
| 789.1 | Persistent vomiting | Symptoms | 0.984 | 0.882 – 1.1 | 0.772 | 348 | 4085 | exclusion | phecode |
| 790 | Nonspecific findings on examination of blood | Symptoms | 1.01 | 0.951 – 1.08 | 0.722 | 1146 | 10904 | exclusion | phecode |
| 790.1 | Elevated sedimentation rate | Symptoms | 0.923 | 0.759 – 1.12 | 0.421 | 114 | 1195 | exclusion | phecode |
| 790.6 | Other abnormal blood chemistry | Symptoms | 1.01 | 0.97 – 1.04 | 0.744 | 3759 | 19115 | exclusion | phecode |
| 790.8 | Elevated C-reactive protein (CRP) | Symptoms | 1.02 | 0.862 – 1.2 | 0.839 | 151 | 1615 | exclusion | phecode |
| 790.9 | Abnormal arterial blood gases | Symptoms | 1.18 | 0.923 – 1.52 | 0.183 | 66 | 740 | exclusion | phecode |
| 791 | Gangrene | Symptoms | 1.02 | 0.843 – 1.24 | 0.812 | 113 | 1425 | exclusion | phecode |
| 792 |
Abnormal Papanicolaou smear of cervix andAbnormal Papanicolaou smear of cervix and cervical HPV
|
Genitourinary | 1 | 0.949 – 1.06 | 0.869 | 1469 | 8174 | exclusion | phecode |
| 792.1 |
Papanicolaou smear of cervix or vagina withPapanicolaou smear of cervix or vagina with atypical squamous cells
|
Genitourinary | 0.998 | 0.915 – 1.09 | 0.971 | 568 | 5409 | exclusion | phecode |
| 794 |
Abnormal results of other function studiesAbnormal results of other function studies (bladder, pancreas, placenta, spleen, etc)
|
Symptoms | 1.01 | 0.883 – 1.16 | 0.846 | 230 | 2486 | exclusion | phecode |
| 795 |
Other and nonspecific abnormal cytologicalOther and nonspecific abnormal cytological, histological and immunological findings
|
Symptoms | 1.05 | 0.986 – 1.12 | 0.128 | 1101 | 10894 | exclusion | phecode |
| 795.8 | Abnormal tumor markers | Symptoms | 0.993 | 0.923 – 1.07 | 0.84 | 830 | 6518 | exclusion | phecode |
| 795.81 | Elevated carcinoembryonic antigen [CEA] | Symptoms | 0.991 | 0.69 – 1.42 | 0.959 | 29 | 300 | exclusion | phecode |
| 795.82 | Elevated cancer antigen 125 [CA 125] | Symptoms | 0.964 | 0.786 – 1.18 | 0.721 | 98 | 1016 | exclusion | phecode |
| 796 | Elevated prostate specific antigen [PSA] | Genitourinary | 1 | 0.931 – 1.08 | 0.976 | 986 | 4057 | exclusion | phecode |
| 797 | Shock | Symptoms | 0.942 | 0.828 – 1.07 | 0.369 | 257 | 2812 | exclusion | phecode |
| 797.1 | Cardiogenic shock | Symptoms | 1.12 | 0.894 – 1.39 | 0.334 | 85 | 1098 | exclusion | phecode |
| 798 | Malaise and fatigue | Symptoms | 1 | 0.975 – 1.04 | 0.755 | 5736 | 17975 | exclusion | phecode |
| 798.1 | Chronic fatigue syndrome | Symptoms | 0.952 | 0.89 – 1.02 | 0.16 | 951 | 9048 | exclusion | phecode |
| 800 | Fracture of lower limb | Injuries & Poisonings | 0.995 | 0.936 – 1.06 | 0.876 | 1173 | 11724 | exclusion | phecode |
| 800.1 | Fracture of neck of femur | Injuries & Poisonings | 1.02 | 0.894 – 1.16 | 0.777 | 241 | 2428 | exclusion | phecode |
| 800.2 | Fracture of unspecified part of femur | Injuries & Poisonings | 0.939 | 0.837 – 1.05 | 0.287 | 326 | 3238 | exclusion | phecode |
| 800.3 | Fracture of tibia and fibula | Injuries & Poisonings | 0.952 | 0.865 – 1.05 | 0.318 | 466 | 4644 | exclusion | phecode |
| 800.4 | Fracture of patella | Injuries & Poisonings | 1.08 | 0.931 – 1.26 | 0.299 | 179 | 1761 | exclusion | phecode |
| 801 | Fracture of ankle and foot | Injuries & Poisonings | 1.04 | 0.982 – 1.1 | 0.176 | 1264 | 11855 | exclusion | phecode |
| 801.1 | Fracture of foot | Injuries & Poisonings | 1.06 | 0.972 – 1.15 | 0.194 | 602 | 5866 | exclusion | phecode |
| 802 | Fracture of pelvis | Injuries & Poisonings | 1.01 | 0.871 – 1.18 | 0.874 | 188 | 1885 | exclusion | phecode |
| 803 | Fracture of upper limb | Injuries & Poisonings | 0.994 | 0.934 – 1.06 | 0.848 | 1125 | 10655 | exclusion | phecode |
| 803.1 | Fracture of humerus | Injuries & Poisonings | 1.01 | 0.908 – 1.12 | 0.894 | 391 | 3752 | exclusion | phecode |
| 803.2 | Fracture of radius and ulna | Injuries & Poisonings | 0.992 | 0.913 – 1.08 | 0.852 | 631 | 5909 | exclusion | phecode |
| 803.21 | Colles' fracture | Injuries & Poisonings | 0.966 | 0.82 – 1.14 | 0.674 | 165 | 1488 | exclusion | phecode |
| 803.3 | Fracture of clavicle or scapula | Injuries & Poisonings | 1.04 | 0.917 – 1.18 | 0.539 | 263 | 2649 | exclusion | phecode |
| 804 | Fracture of hand or wrist | Injuries & Poisonings | 0.989 | 0.922 – 1.06 | 0.748 | 894 | 8493 | exclusion | phecode |
| 805 |
Fracture of vertebral column without mention ofFracture of vertebral column without mention of spinal cord injury
|
Injuries & Poisonings | 0.888 | 0.815 – 0.967 | 0.00653 | 588 | 6401 | exclusion | phecode |
| 807 | Fracture of ribs | Injuries & Poisonings | 0.95 | 0.843 – 1.07 | 0.395 | 295 | 3255 | exclusion | phecode |
| 809 | Fracture of unspecified bones | Injuries & Poisonings | 0.961 | 0.911 – 1.01 | 0.147 | 1513 | 14561 | exclusion | phecode |
| 816 | Cerebral laceration and contusion | Injuries & Poisonings | 1.18 | 0.774 – 1.79 | 0.444 | 20 | 269 | exclusion | phecode |
| 817 | Concussion | Injuries & Poisonings | 0.966 | 0.885 – 1.05 | 0.431 | 558 | 5550 | exclusion | phecode |
| 818 | Intracranial hemorrhage (injury) | Injuries & Poisonings | 1.04 | 0.872 – 1.23 | 0.687 | 132 | 1453 | exclusion | phecode |
| 818.1 | Subdural hemorrhage (injury) | Injuries & Poisonings | 0.839 | 0.603 – 1.17 | 0.298 | 33 | 407 | exclusion | phecode |
| 818.2 | Subarachnoid hemorrhage (injury) | Injuries & Poisonings | 1.03 | 0.758 – 1.39 | 0.871 | 41 | 484 | exclusion | phecode |
| 819 |
Skull and face fracture and other intercranialSkull and face fracture and other intercranial injury
|
Injuries & Poisonings | 0.972 | 0.913 – 1.03 | 0.367 | 1107 | 11893 | exclusion | phecode |
| 830 | Dislocation | Injuries & Poisonings | 1.02 | 0.974 – 1.06 | 0.429 | 2259 | 17525 | exclusion | phecode |
| 835 | Internal derangement of knee | Injuries & Poisonings | 1.02 | 0.964 – 1.08 | 0.478 | 1337 | 11210 | exclusion | phecode |
| 836 | Traumatic arthropathy | Injuries & Poisonings | 0.933 | 0.815 – 1.07 | 0.319 | 231 | 2311 | exclusion | phecode |
| 840 | Sprains and strains | Injuries & Poisonings | 1.01 | 0.972 – 1.04 | 0.749 | 4495 | 18757 | exclusion | phecode |
| 840.1 | Muscle/tendon sprain | Injuries & Poisonings | 1.06 | 0.927 – 1.2 | 0.412 | 267 | 2483 | exclusion | phecode |
| 840.2 | Rotator cuff (capsule) sprain | Injuries & Poisonings | 1.07 | 0.991 – 1.15 | 0.0843 | 805 | 7549 | exclusion | phecode |
| 840.3 | Joint/ligament sprain | Injuries & Poisonings | 0.986 | 0.937 – 1.04 | 0.593 | 1760 | 12904 | exclusion | phecode |
| 841 | Sprains and strains of back and neck | Injuries & Poisonings | 1.01 | 0.935 – 1.08 | 0.881 | 814 | 7970 | exclusion | phecode |
| 842 | Other sprains and strains | Injuries & Poisonings | 0.996 | 0.925 – 1.07 | 0.921 | 798 | 7221 | exclusion | phecode |
| 850 | Hemorrhage or hematoma complicating a procedure | Injuries & Poisonings | 0.979 | 0.914 – 1.05 | 0.543 | 920 | 10183 | exclusion | phecode |
| 851 |
Complications of transplants and reattachedComplications of transplants and reattached limbs
|
Injuries & Poisonings | 0.979 | 0.924 – 1.04 | 0.477 | 1298 | 13694 | exclusion | phecode |
| 853 | Complication of colostomy or enterostomy | Injuries & Poisonings | 0.867 | 0.745 – 1.01 | 0.0661 | 181 | 2257 | exclusion | phecode |
| 854 |
Complications of cardiac/vascular deviceComplications of cardiac/vascular device, implant, and graft
|
Injuries & Poisonings | 1 | 0.934 – 1.08 | 0.938 | 826 | 9597 | exclusion | phecode |
| 855 |
Complication of nervous system device, implantComplication of nervous system device, implant, and graft
|
Injuries & Poisonings | 0.985 | 0.826 – 1.18 | 0.87 | 138 | 1309 | exclusion | phecode |
| 856 |
Vascular complications of surgery and medicalVascular complications of surgery and medical procedures
|
Injuries & Poisonings | 0.894 | 0.736 – 1.09 | 0.258 | 116 | 1440 | exclusion | phecode |
| 857 |
Mechanical complication of unspecifiedMechanical complication of unspecified genitourinary device, implant, and graft
|
Injuries & Poisonings | 1.06 | 0.974 – 1.15 | 0.176 | 603 | 6517 | exclusion | phecode |
| 858 | Complication of internal orthopedic device | Injuries & Poisonings | 0.951 | 0.893 – 1.01 | 0.124 | 1085 | 11219 | exclusion | phecode |
| 859 |
Complication due to other implant and internalComplication due to other implant and internal device
|
Injuries & Poisonings | 0.983 | 0.918 – 1.05 | 0.621 | 919 | 10584 | exclusion | phecode |
| 860 | Bone marrow or stem cell transplant | Neoplasms | 0.767 | 0.604 – 0.973 | 0.0289 | 72 | 799 | exclusion | phecode |
| 870 | Open wounds of head; neck; and trunk | Injuries & Poisonings | 1 | 0.953 – 1.05 | 0.992 | 1889 | 18552 | exclusion | phecode |
| 870.1 | Open wound or laceration of eye or eyelid | Injuries & Poisonings | 0.981 | 0.797 – 1.21 | 0.855 | 92 | 1031 | exclusion | phecode |
| 870.2 | Open wound of ear | Injuries & Poisonings | 1.05 | 0.819 – 1.34 | 0.706 | 70 | 744 | exclusion | phecode |
| 870.3 | Other open wound of head and face | Injuries & Poisonings | 1.08 | 0.995 – 1.17 | 0.0654 | 655 | 6557 | exclusion | phecode |
| 870.4 | Open wound of nose and sinus | Injuries & Poisonings | 0.967 | 0.804 – 1.16 | 0.72 | 118 | 1000 | exclusion | phecode |
| 870.5 | Open wound of lip and mouth | Injuries & Poisonings | 1.04 | 0.868 – 1.24 | 0.696 | 120 | 1292 | exclusion | phecode |
| 870.6 | Open wound of neck | Injuries & Poisonings | 0.868 | 0.683 – 1.1 | 0.245 | 73 | 932 | exclusion | phecode |
| 870.8 | Open wound of genital organs | Injuries & Poisonings | 0.955 | 0.749 – 1.22 | 0.707 | 63 | 728 | exclusion | phecode |
| 871 | Open wounds of extremities | Injuries & Poisonings | 1.03 | 0.98 – 1.08 | 0.238 | 1683 | 16574 | exclusion | phecode |
| 871.1 | Open wound of hand except finger(s) | Injuries & Poisonings | 1 | 0.884 – 1.13 | 0.988 | 278 | 2873 | exclusion | phecode |
| 871.2 | Open wound of finger(s) | Injuries & Poisonings | 1.07 | 0.974 – 1.17 | 0.161 | 507 | 4972 | exclusion | phecode |
| 871.3 | Open wound of foot except toe(s) alone | Injuries & Poisonings | 1.11 | 0.969 – 1.28 | 0.13 | 228 | 2422 | exclusion | phecode |
| 871.4 | Open wound of toe(s) | Injuries & Poisonings | 1.14 | 0.962 – 1.35 | 0.131 | 147 | 1447 | exclusion | phecode |
| 872 | Traumatic amputation | Injuries & Poisonings | 1.13 | 0.985 – 1.3 | 0.081 | 217 | 2581 | exclusion | phecode |
| 874 | Complication of amputation stump | Injuries & Poisonings | 1.01 | 0.779 – 1.31 | 0.93 | 61 | 777 | exclusion | phecode |
| 875 | Non-healing surgical wound | Injuries & Poisonings | 0.999 | 0.879 – 1.13 | 0.982 | 254 | 2785 | exclusion | phecode |
| 876 |
Posttraumatic wound infection not elsewherePosttraumatic wound infection not elsewhere classified
|
Injuries & Poisonings | 1 | 0.897 – 1.12 | 0.957 | 333 | 3852 | exclusion | phecode |
| 907 | Injuries to the nervous system | Injuries & Poisonings | 1.12 | 1.02 – 1.24 | 0.0231 | 469 | 4961 | exclusion | phecode |
| 910 | Superficial injury, infected | Injuries & Poisonings | 0.922 | 0.707 – 1.2 | 0.548 | 65 | 588 | exclusion | phecode |
| 911 | Blister | Injuries & Poisonings | 1.24 | 1.05 – 1.46 | 0.0122 | 155 | 1476 | exclusion | phecode |
| 912 | Insect bite | Injuries & Poisonings | 0.987 | 0.873 – 1.12 | 0.837 | 290 | 2483 | exclusion | phecode |
| 913 | Toxic effect of venom | Injuries & Poisonings | 0.945 | 0.81 – 1.1 | 0.467 | 183 | 1759 | exclusion | phecode |
| 916 | Contusion | Injuries & Poisonings | 1.01 | 0.964 – 1.06 | 0.705 | 2118 | 19225 | exclusion | phecode |
| 930 | Allergic reaction to food | Injuries & Poisonings | 0.975 | 0.885 – 1.07 | 0.606 | 455 | 4036 | exclusion | phecode |
| 931 |
Contact dermatitis and other eczema due toContact dermatitis and other eczema due to plants [except food]
|
Dermatologic | 0.988 | 0.888 – 1.1 | 0.822 | 410 | 3596 | exclusion | phecode |
| 938 | Dermatitis due to solar radiation | Dermatologic | 1.01 | 0.968 – 1.05 | 0.696 | 2954 | 13777 | exclusion | phecode |
| 938.1 | Acute dermatitis due to solar radiation | Dermatologic | 1.08 | 0.885 – 1.32 | 0.445 | 108 | 1067 | exclusion | phecode |
| 938.2 | Chronic dermatitis due to solar radiation | Dermatologic | 1.01 | 0.967 – 1.05 | 0.704 | 2825 | 13530 | exclusion | phecode |
| 939 |
Atopic/contact dermatitis due to other orAtopic/contact dermatitis due to other or unspecified
|
Dermatologic | 1.01 | 0.973 – 1.05 | 0.594 | 3638 | 16015 | exclusion | phecode |
| 939.1 | Contact and allergic dermatitis of eyelid | Dermatologic | 1.15 | 0.887 – 1.49 | 0.291 | 58 | 460 | exclusion | phecode |
| 941 | Adverse reaction to serum or vaccine | Injuries & Poisonings | 1.12 | 0.918 – 1.36 | 0.268 | 105 | 920 | exclusion | phecode |
| 942 | Infusion and transfusion reaction | Injuries & Poisonings | 1.1 | 0.93 – 1.31 | 0.258 | 144 | 1297 | exclusion | phecode |
| 946 | Anaphylactic shock NOS | Injuries & Poisonings | 0.901 | 0.798 – 1.02 | 0.0936 | 293 | 2473 | exclusion | phecode |
| 947 | Urticaria | Dermatologic | 1.05 | 0.97 – 1.14 | 0.221 | 680 | 6025 | exclusion | phecode |
| 949 | Allergies, other | Injuries & Poisonings | 0.984 | 0.949 – 1.02 | 0.372 | 3912 | 15982 | exclusion | phecode |
| 952 |
Spinal cord injury without evidence of spinalSpinal cord injury without evidence of spinal bone injury
|
Injuries & Poisonings | 1.15 | 0.999 – 1.32 | 0.0514 | 216 | 2450 | exclusion | phecode |
| 957 | Injury to other and unspecified nerves | Injuries & Poisonings | 1.09 | 0.847 – 1.4 | 0.512 | 64 | 691 | exclusion | phecode |
| 958 |
Certain early complications of trauma orCertain early complications of trauma or procedure
|
Injuries & Poisonings | 0.991 | 0.904 – 1.09 | 0.853 | 492 | 5965 | exclusion | phecode |
| 958.1 | Postoperative shock | Injuries & Poisonings | 1.02 | 0.806 – 1.29 | 0.88 | 72 | 798 | exclusion | phecode |
| 958.2 | Traumatic and surgical subcutaneous emphysema | Injuries & Poisonings | 1.18 | 0.853 – 1.64 | 0.316 | 38 | 563 | exclusion | phecode |
| 960 | Poisoning by antibiotics | Injuries & Poisonings | 1.02 | 0.956 – 1.08 | 0.578 | 1118 | 11018 | exclusion | phecode |
| 960.1 |
Adverse effects of antibacterials (notAdverse effects of antibacterials (not penicillins)
|
Injuries & Poisonings | 0.96 | 0.82 – 1.12 | 0.607 | 171 | 1679 | exclusion | phecode |
| 960.2 | Allergy/adverse effect of penicillin | Injuries & Poisonings | 1.01 | 0.938 – 1.09 | 0.739 | 735 | 7980 | exclusion | phecode |
| 961 | Poisoning by other anti-infectives | Injuries & Poisonings | 1 | 0.887 – 1.13 | 0.988 | 279 | 2657 | exclusion | phecode |
| 961.1 | Poisoning/allergy of sulfonamides | Injuries & Poisonings | 0.998 | 0.91 – 1.1 | 0.972 | 496 | 5196 | exclusion | phecode |
| 962 | Poisoning by hormones and synthetic substitutes | Injuries & Poisonings | 0.976 | 0.878 – 1.09 | 0.654 | 389 | 4067 | exclusion | phecode |
| 962.1 |
Adrenal cortical steroids causing adverseAdrenal cortical steroids causing adverse effects in therapeutic use
|
Injuries & Poisonings | 0.902 | 0.773 – 1.05 | 0.192 | 179 | 1906 | exclusion | phecode |
| 962.2 |
Insulins and antidiabetic agents causingInsulins and antidiabetic agents causing adverse effects in therapeutic use
|
Injuries & Poisonings | 0.952 | 0.657 – 1.38 | 0.794 | 31 | 312 | exclusion | phecode |
| 962.3 |
Hormones and synthetic substitutes causingHormones and synthetic substitutes causing adverse effects in therapeutic use
|
Injuries & Poisonings | 1.03 | 0.904 – 1.18 | 0.62 | 234 | 2461 | exclusion | phecode |
| 963 | Poisoning by primarily systemic agents | Injuries & Poisonings | 1.02 | 0.958 – 1.08 | 0.597 | 1269 | 12105 | exclusion | phecode |
| 963.1 |
Antineoplastic and immunosuppressive drugsAntineoplastic and immunosuppressive drugs causing adverse effects
|
Injuries & Poisonings | 1.02 | 0.958 – 1.08 | 0.59 | 1240 | 11866 | exclusion | phecode |
| 964 |
Poisoning by agents primarily affecting bloodPoisoning by agents primarily affecting blood constituents
|
Injuries & Poisonings | 0.878 | 0.781 – 0.988 | 0.0309 | 307 | 3493 | exclusion | phecode |
| 964.1 | Anticoagulants causing adverse effects | Injuries & Poisonings | 0.866 | 0.768 – 0.978 | 0.02 | 292 | 3319 | exclusion | phecode |
| 965 |
Poisoning by analgesics, antipyretics, andPoisoning by analgesics, antipyretics, and antirheumatics
|
Injuries & Poisonings | 1.03 | 0.928 – 1.14 | 0.579 | 394 | 4410 | exclusion | phecode |
| 965.1 |
Opiates and related narcotics causing adverseOpiates and related narcotics causing adverse effects in therapeutic use
|
Injuries & Poisonings | 1.03 | 0.951 – 1.13 | 0.424 | 609 | 7177 | exclusion | phecode |
| 965.3 |
Salicylates causing adverse effects inSalicylates causing adverse effects in therapeutic use
|
Injuries & Poisonings | 1.2 | 0.919 – 1.56 | 0.184 | 63 | 560 | exclusion | phecode |
| 966 |
Poisoning by anticonvulsants andPoisoning by anticonvulsants and anti-Parkinsonism drugs
|
Injuries & Poisonings | 0.862 | 0.623 – 1.19 | 0.371 | 40 | 495 | exclusion | phecode |
| 967 |
Adverse effects of sedatives or other centralAdverse effects of sedatives or other central nervous system depressants and anesthetics
|
Injuries & Poisonings | 0.968 | 0.894 – 1.05 | 0.43 | 652 | 6415 | exclusion | phecode |
| 969 | Poisoning by psychotropic agents | Injuries & Poisonings | 1.14 | 0.928 – 1.39 | 0.216 | 100 | 1463 | exclusion | phecode |
| 971 |
Poisoning by drugs primarily affecting thePoisoning by drugs primarily affecting the autonomic nervous system
|
Injuries & Poisonings | 1.29 | 0.91 – 1.82 | 0.154 | 34 | 296 | exclusion | phecode |
| 972 |
Poisoning by agents primarily affecting thePoisoning by agents primarily affecting the cardiovascular system
|
Injuries & Poisonings | 1.19 | 0.979 – 1.45 | 0.0802 | 120 | 1307 | exclusion | phecode |
| 972.1 |
Cardiac rhythm regulators causing adverseCardiac rhythm regulators causing adverse effects in therapeutic use
|
Injuries & Poisonings | 1.14 | 0.805 – 1.63 | 0.455 | 35 | 360 | exclusion | phecode |
| 972.6 | Antihypertensive agents causing adverse effects | Injuries & Poisonings | 1.09 | 0.802 – 1.48 | 0.58 | 42 | 474 | exclusion | phecode |
| 974 |
Poisoning by water, mineral, and uric acidPoisoning by water, mineral, and uric acid metabolism drugs
|
Injuries & Poisonings | 1.26 | 0.959 – 1.65 | 0.0979 | 53 | 555 | exclusion | phecode |
| 975 |
Poisoning by agents primarily acting on thePoisoning by agents primarily acting on the smooth and skeletal muscles and respiratory system
|
Injuries & Poisonings | 0.951 | 0.688 – 1.32 | 0.761 | 43 | 425 | exclusion | phecode |
| 976 |
Poisoning by agents primarily affecting skin &Poisoning by agents primarily affecting skin & mucous membrane, ophthalmological, otorhinolaryngological, & dental drugs
|
Injuries & Poisonings | 1.09 | 0.772 – 1.53 | 0.633 | 31 | 368 | exclusion | phecode |
| 977 | Personal history of allergy to medicinal agents | Injuries & Poisonings | 0.978 | 0.909 – 1.05 | 0.555 | 792 | 8225 | exclusion | phecode |
| 979 | Adverse drug events and drug allergies | Injuries & Poisonings | 1.01 | 0.964 – 1.07 | 0.58 | 1696 | 15692 | exclusion | phecode |
| 980 |
Encounter for long-term (current) use ofEncounter for long-term (current) use of antibiotics
|
Infectious Diseases | 1.07 | 0.985 – 1.16 | 0.11 | 644 | 6405 | exclusion | phecode |
| 985 | Toxic effect of other metals | Injuries & Poisonings | 1.04 | 0.671 – 1.6 | 0.871 | 21 | 268 | exclusion | phecode |
| 989 |
Toxic effect of other substances, chieflyToxic effect of other substances, chiefly nonmedicinal as to source
|
Injuries & Poisonings | 1.04 | 0.804 – 1.36 | 0.745 | 59 | 642 | exclusion | phecode |
| 990 | Effects radiation NOS | Injuries & Poisonings | 0.987 | 0.937 – 1.04 | 0.63 | 1626 | 15195 | exclusion | phecode |
| 994 | Sepsis and SIRS | Injuries & Poisonings | 1.07 | 1 – 1.15 | 0.0458 | 893 | 10264 | exclusion | phecode |
| 994.1 | Systemic inflammatory response syndrome (SIRS) | Injuries & Poisonings | 1.02 | 0.85 – 1.22 | 0.844 | 126 | 1465 | exclusion | phecode |
| 994.2 | Sepsis | Injuries & Poisonings | 1.07 | 1 – 1.15 | 0.0483 | 853 | 9726 | exclusion | phecode |
| 994.21 | Septic shock | Injuries & Poisonings | 1.12 | 0.979 – 1.29 | 0.0966 | 226 | 2929 | exclusion | phecode |