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Scores Smoking initiation UK Biobank (UKB) PheWAS analysis

Smoking initiation — UK Biobank (UKB) PRS PheWAS

PRS model
PRS ID exprsweb-smoker-yes-smokinginitiation-lassosum-ukb-20211120Legacy LASSOSUMlassosumLarge GWAS

Evaluation cohort: UK Biobank (UKB).

This page pairs the PheWAS plot with the full sortable table for the all-subject and exclusion scans.

Read the all-subject and exclusion scans separately. The combined view is only a browsing aid, and the selected-phecode panel below is only meaningful when the same phecode exists in both scans.

ExPRS exclusion definition

Exclusion cohort: individuals without Smoking initiation.

For this ExPRS, the exclusion sensitivity scan removes individuals with the exposure itself before rerunning the PheWAS. This is an exposure-based sensitivity analysis rather than a diagnosis-based exclusion.

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Signal overview

The plot gives a quick view of the currently visible associations. Click a point to pin its details, inspect that phecode across scans when both rows exist, or open the matching phecode detail page.

810 rows visible 17 categories
Phecode Description Category OR 95% CI P value Cases Controls Analysis Link
008 Intestinal infection Infectious Diseases 1.14 1.12 – 1.17 4.14e-32 8842 88430 all phecode
008.5 Bacterial enteritis Infectious Diseases 1.19 1.14 – 1.23 3.67e-17 2718 27172 all phecode
008.52 Intestinal infection due to C. difficile Infectious Diseases 1.12 1.03 – 1.21 0.0055 653 6533 all phecode
008.6 Viral Enteritis Infectious Diseases 1.1 1.02 – 1.18 0.01 862 8622 all phecode
008.7 Intestinal infection due to protozoa Infectious Diseases 0.898 0.686 – 1.18 0.435 55 550 all phecode
010 Tuberculosis Infectious Diseases 1.13 0.962 – 1.33 0.135 166 1659 all phecode
038 Septicemia Infectious Diseases 1.1 1.06 – 1.13 1.63e-08 4175 41776 all phecode
038.1 Gram negative septicemia Infectious Diseases 1.07 0.995 – 1.15 0.0688 850 8501 all phecode
038.2 Gram positive septicemia Infectious Diseases 1.09 0.996 – 1.2 0.0608 494 4978 all phecode
041 Bacterial infection NOS Infectious Diseases 1.15 1.13 – 1.18 3.11e-50 12017 120377 all phecode
041.1 Staphylococcus infections Infectious Diseases 1.18 1.13 – 1.22 4.77e-18 3128 31348 all phecode
041.2 Streptococcus infection Infectious Diseases 1.19 1.13 – 1.25 3.12e-11 1641 16433 all phecode
041.4 E. coli Infectious Diseases 1.15 1.11 – 1.2 1.2e-12 2730 27319 all phecode
053 Herpes zoster Infectious Diseases 1.17 1.06 – 1.3 0.00202 411 4137 all phecode
053.1 Herpes zoster with nervous system complications Infectious Diseases 1.2 0.976 – 1.48 0.0843 95 949 all phecode
054 Herpes simplex Infectious Diseases 1.14 0.99 – 1.31 0.0684 211 2107 all phecode
070 Viral hepatitis Infectious Diseases 1.39 1.27 – 1.51 9.2e-14 590 5916 all phecode
070.1 Viral hepatitis A Infectious Diseases 1.19 0.92 – 1.53 0.189 69 690 all phecode
070.2 Viral hepatitis B Infectious Diseases 1.42 1.18 – 1.71 0.000202 132 1330 all phecode
070.3 Viral hepatitis C Infectious Diseases 1.74 1.52 – 2 9.3e-16 255 2568 all phecode
070.4 Chronic hepatitis Infectious Diseases 1.07 0.94 – 1.21 0.311 276 2767 all phecode
070.9 Hepatitis NOS Infectious Diseases 1.14 1.04 – 1.26 0.00768 428 4287 all phecode
071 Human immunodeficiency virus [HIV] disease Infectious Diseases 1.21 1.02 – 1.44 0.0258 147 1467 all phecode
071.1 HIV infection, symptomatic Infectious Diseases 1.24 1.03 – 1.5 0.0259 117 1168 all phecode
078 Viral warts & HPV Infectious Diseases 1.06 0.994 – 1.13 0.0738 1004 10036 all phecode
079 Viral infection Infectious Diseases 1.06 1.02 – 1.11 0.00205 2769 27694 all phecode
079.1 Varicella infection Infectious Diseases 1.06 0.818 – 1.38 0.65 64 640 all phecode
080 Postoperative infection Infectious Diseases 1.16 1.12 – 1.19 9.25e-21 4473 44775 all phecode
081
Infection/inflammation of internal prosthetic
Infection/inflammation of internal prosthetic device; implant; and graft
 Infectious Diseases 1.16 1.11 – 1.21 2.56e-12 2477 24765 all phecode
090
Sexually transmitted infections (not HIV or
Sexually transmitted infections (not HIV or hepatitis)
 Infectious Diseases 1.22 0.96 – 1.55 0.104 71 709 all phecode
1000 Burns Injuries & Poisonings 1.07 0.984 – 1.17 0.113 578 5796 all phecode
1001 Foreign body injury Injuries & Poisonings 1.04 0.98 – 1.1 0.194 1199 12007 all phecode
1002
Symptoms concerning nutrition, metabolism, and
Symptoms concerning nutrition, metabolism, and development
 Injuries & Poisonings 1.09 1.06 – 1.13 1.99e-10 5480 54819 all phecode
1004
Other signs and symptoms involving emotional
Other signs and symptoms involving emotional state
 Injuries & Poisonings 1.27 1.13 – 1.42 7.5e-05 300 2997 all phecode
1005 Other symptoms Injuries & Poisonings 1.18 1.12 – 1.25 1.75e-09 1444 14422 all phecode
1006 Crushing injury Injuries & Poisonings 1.12 0.98 – 1.27 0.0983 256 2558 all phecode
1007 Injury to blood vessels Injuries & Poisonings 1.28 1.13 – 1.46 0.000163 256 2559 all phecode
1008 Crushing or internal injury to organs Injuries & Poisonings 1.11 1.05 – 1.19 0.000835 1013 10132 all phecode
1009 Injury, NOS Injuries & Poisonings 1.09 1.07 – 1.12 1.81e-14 8482 84911 all phecode
1010 Other tests Injuries & Poisonings 1.1 1.07 – 1.13 8.27e-13 5945 59512 all phecode
1011 Complications of surgical and medical procedures Injuries & Poisonings 1.13 1.1 – 1.15 2.76e-27 9152 91588 all phecode
1012 Late effect Injuries & Poisonings 0.967 0.788 – 1.19 0.751 105 1057 all phecode
1013 Asphyxia and hypoxemia Injuries & Poisonings 1.2 1.07 – 1.35 0.00226 316 3168 all phecode
1014 Effects of heat, cold and air pressure Injuries & Poisonings 1.01 0.79 – 1.3 0.907 66 659 all phecode
1015 Effects of other external causes Injuries & Poisonings 1.19 1.15 – 1.23 2.58e-27 4226 42294 all phecode
1019
Other ill-defined and unknown causes of
Other ill-defined and unknown causes of morbidity and mortality
 Injuries & Poisonings 1.1 1.08 – 1.12 2.58e-29 15895 159019 all phecode
110 Dermatophytosis / Dermatomycosis Infectious Diseases 1.05 0.931 – 1.19 0.421 279 2810 all phecode
110.1 Dermatophytosis Infectious Diseases 1.03 0.911 – 1.16 0.64 273 2750 all phecode
110.11 Dermatophytosis of nail Infectious Diseases 1.08 0.847 – 1.37 0.553 74 756 all phecode
110.12 Althete's foot Infectious Diseases 1 0.845 – 1.19 0.985 141 1410 all phecode
112 Candidiasis Infectious Diseases 1.22 1.17 – 1.28 4.29e-18 2126 21275 all phecode
117 Mycoses Infectious Diseases 1.13 1 – 1.28 0.0508 272 2719 all phecode
117.4 Aspergillosis Infectious Diseases 1.05 0.894 – 1.23 0.567 165 1650 all phecode
130 Spirochetal infection Infectious Diseases 0.935 0.744 – 1.18 0.565 80 800 all phecode
133 Arthropod-borne diseases Infectious Diseases 1.2 0.93 – 1.55 0.161 69 689 all phecode
134 Helminthiases Infectious Diseases 1.06 0.877 – 1.28 0.541 127 1267 all phecode
134.1 Intestinal helminthiases Infectious Diseases 1 0.817 – 1.23 0.979 106 1058 all phecode
136 Other infectious and parasitic diseases Infectious Diseases 0.985 0.855 – 1.13 0.831 205 2050 all phecode
145 Cancer of mouth Neoplasms 1.16 1.07 – 1.25 0.000436 642 6415 all phecode
145.2 Cancer of tongue Neoplasms 1.17 1.04 – 1.31 0.00992 310 3096 all phecode
145.3 Cancer of major salivary glands Neoplasms 1.07 0.875 – 1.3 0.522 105 1049 all phecode
145.5 Cancer of the mouth floor Neoplasms 1.21 0.927 – 1.59 0.16 54 539 all phecode
149 Cancer of larynx, pharynx, nasal cavities Neoplasms 1.27 1.18 – 1.38 4.26e-09 635 6342 all phecode
149.1 Cancer of oropharynx Neoplasms 1.21 1.06 – 1.38 0.00387 252 2517 all phecode
149.4 Cancer of larynx Neoplasms 1.4 1.24 – 1.59 9.46e-08 265 2640 all phecode
149.9 Cancer of of nasal cavities Neoplasms 1.06 0.819 – 1.37 0.653 57 570 all phecode
150 Cancer of esophagus Neoplasms 1.23 1.14 – 1.32 1.16e-07 762 7630 all phecode
151 Cancer of stomach Neoplasms 1.17 1.07 – 1.27 0.000335 569 5696 all phecode
153 Colorectal cancer Neoplasms 1.05 1.02 – 1.08 0.00144 4580 45799 all phecode
153.2 Colon cancer Neoplasms 1.03 0.996 – 1.07 0.0783 3105 31046 all phecode
153.3
Malignant neoplasm of rectum, rectosigmoid
Malignant neoplasm of rectum, rectosigmoid junction, and anus
 Neoplasms 1.07 1.03 – 1.12 0.00171 2164 21640 all phecode
155 Cancer of liver and intrahepatic bile duct Neoplasms 1.16 1.05 – 1.29 0.00353 400 4008 all phecode
155.1 Malignant neoplasm of liver, primary Neoplasms 1.26 1.07 – 1.48 0.00582 158 1580 all phecode
157 Pancreatic cancer Neoplasms 1.18 1.09 – 1.27 5.93e-05 659 6582 all phecode
158
Neoplasm of unspecified nature of digestive
Neoplasm of unspecified nature of digestive system
 Neoplasms 1.05 0.982 – 1.11 0.164 1063 10635 all phecode
159
Malignant neoplasm of other and ill-defined
Malignant neoplasm of other and ill-defined sites within the digestive organs and peritoneum
 Neoplasms 1.07 1.04 – 1.1 5.03e-07 5567 55694 all phecode
159.2
Malignant neoplasm of small intestine
Malignant neoplasm of small intestine, including duodenum
 Neoplasms 1.01 0.871 – 1.18 0.877 190 1900 all phecode
159.3
Malignant neoplasm of gallbladder and
Malignant neoplasm of gallbladder and extrahepatic bile ducts
 Neoplasms 1.01 0.878 – 1.17 0.852 205 2048 all phecode
159.4
Malignant neoplasm of retroperitoneum and
Malignant neoplasm of retroperitoneum and peritoneum
 Neoplasms 1.1 0.947 – 1.27 0.216 193 1925 all phecode
164 Cancer of intrathoracic organs Neoplasms 0.862 0.657 – 1.13 0.283 60 600 all phecode
165 Cancer within the respiratory system Neoplasms 1.41 1.35 – 1.46 5.21e-64 2824 28235 all phecode
165.1 Cancer of bronchus; lung Neoplasms 1.44 1.38 – 1.51 8.15e-58 2230 22307 all phecode
170 Cancer of bone and connective tissue Neoplasms 1.09 0.991 – 1.2 0.0757 437 4364 all phecode
170.1 Bone cancer Neoplasms 1.13 0.951 – 1.35 0.162 131 1309 all phecode
170.2 Cancer of connective tissue Neoplasms 1.11 0.988 – 1.24 0.0788 331 3303 all phecode
172 Skin cancer Neoplasms 0.977 0.96 – 0.995 0.0106 13495 134987 all phecode
172.1 Melanomas of skin, dx or hx Neoplasms 0.944 0.907 – 0.982 0.00439 2681 26792 all phecode
172.11 Melanomas of skin Neoplasms 0.945 0.908 – 0.983 0.00512 2713 27112 all phecode
172.2 Other non-epithelial cancer of skin Neoplasms 0.985 0.965 – 1 0.122 11000 110056 all phecode
172.3 Carcinoma in situ of skin Neoplasms 1.01 0.937 – 1.1 0.716 666 6656 all phecode
173 Neoplasm of uncertain behavior of skin Neoplasms 0.869 0.747 – 1.01 0.0698 181 1818 all phecode
174 Breast cancer Neoplasms 1.02 1 – 1.04 0.0394 12686 126597 all phecode
174.1 Breast cancer [female] Neoplasms 1.02 1 – 1.04 0.0328 12476 124506 all phecode
174.11 Malignant neoplasm of female breast Neoplasms 1.02 1 – 1.04 0.0245 11757 117502 all phecode
174.3 Neoplasm of uncertain behavior of breast Neoplasms 0.845 0.695 – 1.03 0.0918 115 1148 all phecode
175 Acquired absence of breast Neoplasms 1.09 1.04 – 1.13 0.000135 2400 24010 all phecode
180 Cervical cancer and dysplasia Neoplasms 1.09 1.04 – 1.14 0.000205 2174 21747 all phecode
180.1 Cervical cancer Neoplasms 1.11 0.978 – 1.26 0.107 272 2720 all phecode
180.3
Cervical intraepithelial neoplasia [CIN]
Cervical intraepithelial neoplasia [CIN] [Cervical dysplasia]
 Neoplasms 1.09 1.04 – 1.14 0.000312 2078 20784 all phecode
182 Malignant neoplasm of uterus Neoplasms 0.943 0.889 – 1 0.05 1282 12836 all phecode
184 Cancer of other female genital organs Neoplasms 1.03 0.976 – 1.09 0.268 1378 13772 all phecode
184.1
Malignant neoplasm of ovary and other uterine
Malignant neoplasm of ovary and other uterine adnexa
 Neoplasms 1 0.935 – 1.07 0.997 967 9667 all phecode
184.11 Malignant neoplasm of ovary Neoplasms 1 0.936 – 1.07 0.946 939 9387 all phecode
184.2
Cancer of other female genital organs
Cancer of other female genital organs (excluding uterus and ovary)
 Neoplasms 1.11 0.984 – 1.25 0.0902 305 3049 all phecode
185 Cancer of prostate Neoplasms 0.967 0.942 – 0.993 0.0129 5974 58812 all phecode
187 Cancer of other male genital organs Neoplasms 0.983 0.894 – 1.08 0.728 449 4485 all phecode
187.1
Malignant neoplasm of unspecified male genital
Malignant neoplasm of unspecified male genital organ
 Neoplasms 1.05 0.825 – 1.33 0.703 70 700 all phecode
187.2 Malignant neoplasm of testis Neoplasms 0.98 0.87 – 1.1 0.742 287 2868 all phecode
187.8
Neoplasm of uncertain behavior of male genital
Neoplasm of uncertain behavior of male genital organs
 Neoplasms 0.988 0.817 – 1.19 0.9 110 1098 all phecode
189
Cancer of urinary organs (incl. kidney and
Cancer of urinary organs (incl. kidney and bladder)
 Neoplasms 1.12 1.09 – 1.16 8.16e-13 4160 41604 all phecode
189.1 Cancer of kidney and renal pelvis Neoplasms 1.11 1.04 – 1.18 0.00112 1073 10723 all phecode
189.11 Malignant neoplasm of kidney, except pelvis Neoplasms 1.12 1.05 – 1.19 0.00048 1033 10324 all phecode
189.12 Malignant neoplasm of renal pelvis Neoplasms 0.872 0.676 – 1.13 0.294 66 660 all phecode
189.2 Cancer of bladder Neoplasms 1.14 1.09 – 1.19 1.62e-09 2409 24113 all phecode
189.21 Malignant neoplasm of bladder Neoplasms 1.16 1.11 – 1.21 1.09e-10 2142 21447 all phecode
189.4 Malignant neoplasm of other urinary organs Neoplasms 1.09 0.92 – 1.3 0.316 144 1439 all phecode
190 Cancer of eye Neoplasms 0.915 0.782 – 1.07 0.268 176 1758 all phecode
191
Manlignant and unknown neoplasms of brain and
Manlignant and unknown neoplasms of brain and nervous system
 Neoplasms 1.04 0.966 – 1.13 0.275 689 6879 all phecode
191.1 Cancer of brain and nervous system Neoplasms 1.04 0.953 – 1.13 0.385 566 5650 all phecode
191.11 Cancer of brain Neoplasms 1.07 0.981 – 1.18 0.121 525 5240 all phecode
193 Thyroid cancer Neoplasms 1.02 0.911 – 1.14 0.738 346 3466 all phecode
194 Cancer of other endocrine glands Neoplasms 1.11 0.907 – 1.37 0.304 95 949 all phecode
195 Cancer, suspected or other Neoplasms 1.06 1.04 – 1.07 3.14e-12 16967 165463 all phecode
195.1 Malignant neoplasm, other Neoplasms 1.06 1.04 – 1.08 1.03e-11 16267 159497 all phecode
197 Chemotherapy Neoplasms 1.11 1.09 – 1.12 6.79e-44 21433 213213 all phecode
198 Secondary malignant neoplasm Neoplasms 1.1 1.07 – 1.12 1.34e-17 9552 95503 all phecode
198.1 Secondary malignancy of lymph nodes Neoplasms 1.06 1.03 – 1.09 3.49e-05 5368 53670 all phecode
198.2 Secondary malignancy of respiratory organs Neoplasms 1.11 1.07 – 1.16 1.43e-06 2267 22670 all phecode
198.3
Secondary malignant neoplasm of digestive
Secondary malignant neoplasm of digestive systems
 Neoplasms 1.05 0.992 – 1.1 0.0951 1549 15496 all phecode
198.4 Secondary malignant neoplasm of liver Neoplasms 1.1 1.05 – 1.14 5e-06 2665 26648 all phecode
198.5 Secondary malignancy of brain/spine Neoplasms 1.23 1.15 – 1.32 1.1e-08 848 8473 all phecode
198.6 Secondary malignancy of bone Neoplasms 1.12 1.07 – 1.17 8.7e-07 2161 21600 all phecode
198.7 Secondary malignant neoplasm of skin Neoplasms 1.01 0.868 – 1.17 0.911 188 1890 all phecode
199 Neoplasm of uncertain behavior Neoplasms 1.13 1.07 – 1.2 5.09e-06 1432 14313 all phecode
199.4 Neurofibromatosis Neoplasms 1.04 0.85 – 1.27 0.7 95 950 all phecode
200 Myeloproliferative disease Neoplasms 1.04 0.979 – 1.11 0.19 991 9911 all phecode
200.1 Polycythemia vera Neoplasms 1.08 0.972 – 1.2 0.157 387 3867 all phecode
201 Hodgkin's disease Neoplasms 1.04 0.921 – 1.18 0.501 259 2598 all phecode
202 Cancer of other lymphoid, histiocytic tissue Neoplasms 1.03 0.983 – 1.07 0.244 2264 22709 all phecode
202.2 Non-Hodgkins lymphoma Neoplasms 1.01 0.961 – 1.06 0.731 1802 18073 all phecode
202.21 Nodular lymphoma Neoplasms 1.08 0.969 – 1.2 0.165 363 3647 all phecode
202.24 Large cell lymphoma Neoplasms 0.993 0.911 – 1.08 0.877 581 5824 all phecode
204 Leukemia Neoplasms 1.01 0.96 – 1.06 0.691 1660 16630 all phecode
204.1 Lymphoid leukemia Neoplasms 1.05 0.963 – 1.14 0.266 577 5784 all phecode
204.11 Lymphoid leukemia, acute Neoplasms 0.938 0.708 – 1.24 0.657 56 560 all phecode
204.12 Lymphoid leukemia, chronic Neoplasms 1.05 0.959 – 1.15 0.282 507 5084 all phecode
204.2 Myeloid leukemia Neoplasms 0.985 0.896 – 1.08 0.758 462 4617 all phecode
204.21 Myeloid leukemia, acute Neoplasms 0.991 0.886 – 1.11 0.88 329 3287 all phecode
204.22 Myeloid leukemia, chronic Neoplasms 0.958 0.808 – 1.14 0.626 144 1440 all phecode
204.4 Multiple myeloma Neoplasms 0.967 0.886 – 1.05 0.444 555 5560 all phecode
208 Benign neoplasm of colon Neoplasms 1.12 1.11 – 1.14 8.87e-55 19856 191891 all phecode
210 Benign neoplasm of lip, oral cavity, and pharynx Neoplasms 1.12 1.05 – 1.2 0.000797 978 9781 all phecode
211
Benign neoplasm of other parts of digestive
Benign neoplasm of other parts of digestive system
 Neoplasms 0.994 0.966 – 1.02 0.667 5243 52452 all phecode
212
Benign neoplasm of respiratory and
Benign neoplasm of respiratory and intrathoracic organs
 Neoplasms 1.14 1.02 – 1.27 0.017 347 3466 all phecode
213 Benign neoplasm of bone and articular cartilage Neoplasms 0.991 0.883 – 1.11 0.877 318 3187 all phecode
214 Lipoma Neoplasms 1.1 1.07 – 1.13 8.14e-13 6231 62346 all phecode
214.1 Lipoma of skin and subcutaneous tissue Neoplasms 1.12 1.09 – 1.15 3.64e-13 4585 45872 all phecode
215
Other benign neoplasm of connective and other
Other benign neoplasm of connective and other soft tissue
 Neoplasms 1.09 1.02 – 1.16 0.00689 1107 11061 all phecode
216 Benign neoplasm of skin Neoplasms 0.992 0.969 – 1.02 0.52 7664 76660 all phecode
217 Vascular hamartomas and non-neoplastic nevi Neoplasms 1.11 1.02 – 1.21 0.0126 632 6313 all phecode
217.1 Nevus, non-neoplastic Neoplasms 1.09 1 – 1.19 0.0404 595 5943 all phecode
218 Benign neoplasm of uterus Neoplasms 1.01 0.985 – 1.03 0.567 10023 100200 all phecode
218.1 Uterine leiomyoma Neoplasms 1 0.98 – 1.02 0.972 10241 102376 all phecode
218.2 Other benign neoplasm of uterus Neoplasms 1.05 0.942 – 1.17 0.373 355 3548 all phecode
220 Benign neoplasm of ovary Neoplasms 1.03 0.971 – 1.08 0.357 1445 14483 all phecode
221 Benign neoplasm of other female genital organs Neoplasms 1.14 0.994 – 1.3 0.0609 220 2196 all phecode
222 Benign neoplasm of male genital organs Neoplasms 0.928 0.79 – 1.09 0.359 160 1600 all phecode
223
Benign neoplasm of kidney and other urinary
Benign neoplasm of kidney and other urinary organs
 Neoplasms 1.1 0.94 – 1.28 0.244 173 1729 all phecode
224 Benign neoplasm of eye Neoplasms 1.03 0.86 – 1.23 0.762 129 1299 all phecode
224.1 Benign neoplasm of eye, uveal Neoplasms 1.11 0.868 – 1.43 0.396 67 680 all phecode
225
Benign neoplasm of brain and other parts of
Benign neoplasm of brain and other parts of nervous system
 Neoplasms 0.934 0.869 – 1.01 0.0689 816 8155 all phecode
225.1
Benign neoplasm of brain, cranial nerves
Benign neoplasm of brain, cranial nerves, meninges
 Neoplasms 0.924 0.857 – 0.996 0.0391 775 7756 all phecode
225.2 Benign neoplasm of spinal cord, meninges Neoplasms 1.07 0.819 – 1.41 0.608 59 589 all phecode
226 Benign neoplasm of thyroid glands Neoplasms 0.913 0.805 – 1.04 0.162 266 2664 all phecode
227
Benign neoplasm of other endocrine glands and
Benign neoplasm of other endocrine glands and related structures
 Neoplasms 1.05 0.976 – 1.12 0.203 861 8635 all phecode
227.1 Benign neoplasm of adrenal gland Neoplasms 1.28 1.1 – 1.49 0.00155 186 1857 all phecode
227.2 Benign neoplasm of parathyroid gland Neoplasms 0.982 0.883 – 1.09 0.741 371 3709 all phecode
227.3
Benign neoplasm of pituitary gland and
Benign neoplasm of pituitary gland and craniopharyngeal duct (pouch)
 Neoplasms 1.02 0.904 – 1.15 0.777 309 3114 all phecode
228 Hemangioma and lymphangioma, any site Neoplasms 0.986 0.937 – 1.04 0.597 1596 15966 all phecode
229 Benign neoplasm of unspecified sites Neoplasms 1.01 0.964 – 1.05 0.801 2397 23955 all phecode
240 Simple and unspecified goiter Endocrine/metabolic 1.04 0.958 – 1.13 0.336 600 6016 all phecode
241 Nontoxic nodular goiter Endocrine/metabolic 1.05 0.982 – 1.11 0.165 1107 11092 all phecode
241.1 Nontoxic uninodular goiter Endocrine/metabolic 1.01 0.921 – 1.12 0.777 471 4706 all phecode
241.2 Nontoxic multinodular goiter Endocrine/metabolic 1.07 0.985 – 1.15 0.114 676 6784 all phecode
242 Thyrotoxicosis with or without goiter Endocrine/metabolic 1.07 1.02 – 1.13 0.00355 1854 18531 all phecode
242.1 Graves' disease Endocrine/metabolic 1.15 1.05 – 1.26 0.00381 456 4553 all phecode
242.2 Toxic multinodular goiter Endocrine/metabolic 1.18 0.947 – 1.47 0.141 91 910 all phecode
242.3 Exophthalmos Endocrine/metabolic 1.15 0.967 – 1.36 0.114 138 1379 all phecode
244 Hypothyroidism Endocrine/metabolic 1.1 1.08 – 1.12 3.02e-29 14590 145053 all phecode
244.1 Secondary hypothyroidism Endocrine/metabolic 1.1 1.03 – 1.17 0.00349 1108 11079 all phecode
244.2 Acquired hypothyroidism Endocrine/metabolic 1.09 0.891 – 1.34 0.39 101 1010 all phecode
244.4 Hypothyroidism NOS Endocrine/metabolic 1.11 1.09 – 1.12 1.08e-28 13918 138926 all phecode
245 Thyroiditis Endocrine/metabolic 1.1 0.97 – 1.24 0.138 288 2877 all phecode
245.2 Chronic thyroiditis Endocrine/metabolic 1.11 0.967 – 1.28 0.137 218 2177 all phecode
245.21 Chronic lymphocytic thyroiditis Endocrine/metabolic 1.11 0.959 – 1.28 0.166 210 2097 all phecode
246 Other disorders of thyroid Endocrine/metabolic 1.06 0.953 – 1.17 0.294 397 3975 all phecode
250 Diabetes mellitus Endocrine/metabolic 1.19 1.17 – 1.21 1.09e-116 19787 186006 all phecode
250.1 Type 1 diabetes Endocrine/metabolic 1.13 1.09 – 1.18 9.64e-10 2758 27621 all phecode
250.11 Type 1 diabetes with ketoacidosis Endocrine/metabolic 1.08 0.949 – 1.24 0.236 239 2389 all phecode
250.12 Type 1 diabetes with renal manifestations Endocrine/metabolic 1.13 0.894 – 1.43 0.305 76 770 all phecode
250.13 Type 1 diabetes with ophthalmic manifestations Endocrine/metabolic 1.06 0.96 – 1.16 0.257 473 4744 all phecode
250.14 Type 1 diabetes with neurological manifestations Endocrine/metabolic 1.04 0.881 – 1.22 0.662 160 1610 all phecode
250.2 Type 2 diabetes Endocrine/metabolic 1.2 1.19 – 1.22 1.19e-121 17831 170202 all phecode
250.21 Type 2 diabetes with ketoacidosis Endocrine/metabolic 1.05 0.855 – 1.28 0.652 104 1050 all phecode
250.22 Type 2 diabetes with renal manifestations Endocrine/metabolic 1.12 0.967 – 1.3 0.13 200 2018 all phecode
250.23 Type 2 diabetes with ophthalmic manifestations Endocrine/metabolic 1.23 1.15 – 1.32 6.2e-10 986 9907 all phecode
250.24 Type 2 diabetes with neurological manifestations Endocrine/metabolic 1.26 1.15 – 1.38 1.25e-06 503 5066 all phecode
250.4 Abnormal glucose Endocrine/metabolic 1.16 1.08 – 1.26 0.00014 680 6827 all phecode
250.41 Impaired fasting glucose Endocrine/metabolic 1.17 1.03 – 1.34 0.0154 265 2659 all phecode
250.42 Other abnormal glucose Endocrine/metabolic 1.15 1.04 – 1.27 0.00507 416 4178 all phecode
250.5 Glycosuria or Acetonuria Endocrine/metabolic 1.1 0.919 – 1.32 0.301 131 1308 all phecode
250.6 Polyneuropathy in diabetes Endocrine/metabolic 1.31 1.18 – 1.47 1.39e-06 349 3495 all phecode
250.7 Diabetic retinopathy Endocrine/metabolic 1.15 1.08 – 1.21 2.25e-06 1329 13335 all phecode
251.1 Hypoglycemia Endocrine/metabolic 1.14 1.07 – 1.22 0.000124 932 9370 all phecode
252 Disorders of parathyroid gland Endocrine/metabolic 0.997 0.93 – 1.07 0.93 873 8719 all phecode
252.1 Hyperparathyroidism Endocrine/metabolic 0.993 0.922 – 1.07 0.845 781 7802 all phecode
252.2 Hypoparathyroidism Endocrine/metabolic 1 0.845 – 1.18 1 142 1418 all phecode
253
Disorders of the pituitary gland and its
Disorders of the pituitary gland and its hypothalamic control
 Endocrine/metabolic 1.03 0.953 – 1.11 0.455 681 6821 all phecode
253.1 Pituitary hyperfunction Endocrine/metabolic 1.04 0.893 – 1.21 0.613 187 1867 all phecode
253.11 Acromegaly and gigantism Endocrine/metabolic 1.02 0.824 – 1.25 0.881 95 949 all phecode
253.2 Pituitary hypofunction Endocrine/metabolic 1 0.882 – 1.13 1 260 2618 all phecode
253.3 Diabetes insipidus Endocrine/metabolic 1.01 0.813 – 1.25 0.94 92 919 all phecode
253.7 Other disorders of neurohypophysis Endocrine/metabolic 1.07 0.915 – 1.26 0.386 158 1578 all phecode
255 Disorders of adrenal glands Endocrine/metabolic 1.13 1.04 – 1.23 0.00303 638 6374 all phecode
255.1 Adrenal hyperfunction Endocrine/metabolic 1.11 0.953 – 1.29 0.182 180 1797 all phecode
255.11 Cushing's syndrome Endocrine/metabolic 1.18 0.97 – 1.44 0.0972 103 1029 all phecode
255.12 Hyperaldosteronism Endocrine/metabolic 0.951 0.758 – 1.19 0.669 76 759 all phecode
255.2 Adrenal hypofunction Endocrine/metabolic 1.06 0.952 – 1.18 0.284 362 3617 all phecode
255.21 Glucocorticoid deficiency Endocrine/metabolic 1.07 0.956 – 1.19 0.244 361 3607 all phecode
256 Ovarian dysfunction Endocrine/metabolic 0.915 0.801 – 1.05 0.191 240 2397 all phecode
256.4 Polycystic ovaries Endocrine/metabolic 0.93 0.806 – 1.07 0.319 209 2088 all phecode
257 Testicular dysfunction Endocrine/metabolic 0.938 0.796 – 1.1 0.442 160 1619 all phecode
257.1 Testicular hypofunction Endocrine/metabolic 0.924 0.782 – 1.09 0.356 152 1539 all phecode
258 Iatrogenic endocrine disorders Endocrine/metabolic 1.03 0.843 – 1.26 0.769 102 1020 all phecode
259 Other endocrine disorders Endocrine/metabolic 1.03 0.867 – 1.22 0.752 149 1498 all phecode
260 Protein-calorie malnutrition Endocrine/metabolic 1.13 0.979 – 1.31 0.0949 202 2018 all phecode
260.1 Cachexia Endocrine/metabolic 1.28 0.962 – 1.69 0.0905 51 510 all phecode
260.6 Anorexia Endocrine/metabolic 1.14 1.06 – 1.22 0.000465 830 8317 all phecode
261 Vitamin deficiency Endocrine/metabolic 1.15 1.08 – 1.22 7.93e-06 1199 11974 all phecode
261.2 Vitamin B-complex deficiencies Endocrine/metabolic 1.19 1.1 – 1.28 8.39e-06 755 7541 all phecode
261.4 Vitamin D deficiency Endocrine/metabolic 1.06 0.962 – 1.17 0.236 447 4462 all phecode
261.41 Rickets or osteomalacia Endocrine/metabolic 0.999 0.783 – 1.27 0.991 77 769 all phecode
262 Mineral deficiency NEC Endocrine/metabolic 0.951 0.833 – 1.09 0.464 241 2407 all phecode
269 Proteinuria Endocrine/metabolic 1.12 1 – 1.25 0.0451 338 3378 all phecode
270
Disorders of protein plasma/amino-acid
Disorders of protein plasma/amino-acid transport and metabolism
 Endocrine/metabolic 1.15 1.02 – 1.29 0.0227 303 3028 all phecode
270.3 Disorders of plasma protein metabolism Endocrine/metabolic 1.15 1.01 – 1.31 0.0291 261 2608 all phecode
270.32 Paraproteinemia Endocrine/metabolic 1.22 1.05 – 1.42 0.0107 191 1910 all phecode
270.33 Amyloidosis Endocrine/metabolic 1.16 0.95 – 1.41 0.148 113 1129 all phecode
270.35 Macroglobulinemia Endocrine/metabolic 0.969 0.766 – 1.23 0.794 69 689 all phecode
271
Disorders of carbohydrate transport and
Disorders of carbohydrate transport and metabolism
 Endocrine/metabolic 0.993 0.847 – 1.16 0.929 160 1600 all phecode
271.3
Intestinal disaccharidase deficiencies and
Intestinal disaccharidase deficiencies and disaccharide malabsorption
 Endocrine/metabolic 0.983 0.827 – 1.17 0.841 139 1391 all phecode
272 Disorders of lipoid metabolism Endocrine/metabolic 1.16 1.15 – 1.17 9.58e-142 34835 235433 all phecode
272.1 Hyperlipidemia Endocrine/metabolic 1.16 1.15 – 1.17 4.39e-142 34764 235203 all phecode
272.11 Hypercholesterolemia Endocrine/metabolic 1.16 1.15 – 1.17 1.12e-134 32324 228083 all phecode
272.12 Hyperglyceridemia Endocrine/metabolic 1.12 0.854 – 1.46 0.419 58 580 all phecode
272.13 Mixed hyperlipidemia Endocrine/metabolic 1.19 1.02 – 1.39 0.0316 164 1637 all phecode
272.9 Unspecified disorder of lipoid metabolism Endocrine/metabolic 1.16 1.01 – 1.34 0.0367 211 2109 all phecode
274 Gout and other crystal arthropathies Endocrine/metabolic 1.21 1.17 – 1.25 3.68e-29 3724 37231 all phecode
274.1 Gout Endocrine/metabolic 1.22 1.18 – 1.26 2.2e-26 3171 31705 all phecode
274.11 Gouty arthropathy Endocrine/metabolic 1.02 0.844 – 1.22 0.86 112 1119 all phecode
274.2 Crystal arthropathies Endocrine/metabolic 1.19 1.1 – 1.29 3.88e-05 613 6124 all phecode
274.21 Chondrocalcinosis Endocrine/metabolic 1.2 1.1 – 1.31 2.92e-05 558 5576 all phecode
275 Disorders of mineral metabolism Endocrine/metabolic 1.14 1.09 – 1.19 1.24e-08 2107 21070 all phecode
275.1 Disorders of iron metabolism Hematopoietic 1.14 1.05 – 1.23 0.00182 653 6535 all phecode
275.3 Disorders of magnesium metabolism Endocrine/metabolic 1.21 1.09 – 1.35 0.000349 375 3745 all phecode
275.5 Disorders of calcium/phosphorus metabolism Endocrine/metabolic 1.15 1.08 – 1.22 6.58e-06 1202 12019 all phecode
275.53 Disorders of phosphorus metabolism Endocrine/metabolic 1.2 1.02 – 1.4 0.0248 171 1717 all phecode
276
Disorders of fluid, electrolyte, and acid-base
Disorders of fluid, electrolyte, and acid-base balance
 Endocrine/metabolic 1.14 1.12 – 1.17 5.36e-28 7284 72932 all phecode
276.1 Electrolyte imbalance Endocrine/metabolic 1.14 1.1 – 1.17 8.47e-15 4086 40930 all phecode
276.11 Hyperosmolality and/or hypernatremia Endocrine/metabolic 1.02 0.892 – 1.16 0.813 239 2409 all phecode
276.12 Hyposmolality and/or hyponatremia Endocrine/metabolic 1.11 1.05 – 1.16 4.3e-05 1818 18200 all phecode
276.13 Hyperpotassemia Endocrine/metabolic 1.21 1.13 – 1.29 2.46e-08 969 9728 all phecode
276.14 Hypopotassemia Endocrine/metabolic 1.15 1.09 – 1.22 4.17e-07 1424 14235 all phecode
276.4 Acid-base balance disorder Endocrine/metabolic 1.21 1.14 – 1.28 1.06e-09 1161 11629 all phecode
276.41 Acidosis Endocrine/metabolic 1.19 1.12 – 1.27 3.95e-08 1056 10577 all phecode
276.42 Alkalosis Endocrine/metabolic 1.3 1.07 – 1.58 0.00817 113 1129 all phecode
276.5 Hypovolemia Endocrine/metabolic 1.13 1.09 – 1.17 1.04e-09 2827 28265 all phecode
276.6 Fluid overload Endocrine/metabolic 1.21 1.1 – 1.33 0.000109 451 4535 all phecode
276.8 Polydipsia Endocrine/metabolic 1.19 0.998 – 1.42 0.0524 128 1278 all phecode
277 Other disorders of metabolism Endocrine/metabolic 1.14 1.06 – 1.22 0.000175 899 8977 all phecode
277.4 Disorders of bilirubin excretion Endocrine/metabolic 0.968 0.87 – 1.08 0.553 362 3613 all phecode
277.5 Other disorders of lipoid metabolism Endocrine/metabolic 1.15 1 – 1.32 0.045 230 2298 all phecode
277.51 Lipoprotein disorders Endocrine/metabolic 1.16 0.861 – 1.56 0.331 52 520 all phecode
278 Overweight, obesity and other hyperalimentation Endocrine/metabolic 1.21 1.19 – 1.24 7.94e-82 10804 108289 all phecode
278.1 Obesity Endocrine/metabolic 1.22 1.19 – 1.24 2.3e-83 10642 106670 all phecode
278.3 Localized adiposity Endocrine/metabolic 1.09 0.879 – 1.36 0.422 84 838 all phecode
278.4 Abnormal weight gain Endocrine/metabolic 0.857 0.668 – 1.1 0.225 66 660 all phecode
279 Disorders involving the immune mechanism Endocrine/metabolic 1.16 1.01 – 1.33 0.0323 250 2510 all phecode
279.1 Immunity deficiency Endocrine/metabolic 1.17 1.01 – 1.36 0.0355 209 2100 all phecode
279.11 Deficiency of humoral immunity Endocrine/metabolic 1.16 0.966 – 1.38 0.113 138 1390 all phecode
279.7 Other immunological findings Endocrine/metabolic 0.932 0.821 – 1.06 0.282 248 2478 all phecode
280 Iron deficiency anemias Hematopoietic 1.07 1.04 – 1.09 5.95e-08 7610 76168 all phecode
280.1
Iron deficiency anemias, unspecified or not due
Iron deficiency anemias, unspecified or not due to blood loss
 Hematopoietic 1.07 1.04 – 1.09 7.01e-08 7311 73153 all phecode
280.2
Iron deficiency anemia secondary to blood loss
Iron deficiency anemia secondary to blood loss (chronic)
 Hematopoietic 0.967 0.878 – 1.07 0.498 452 4541 all phecode
281 Other deficiency anemia Hematopoietic 1.14 1.08 – 1.22 2.06e-05 1112 11126 all phecode
281.1 Megaloblastic anemia Hematopoietic 1.13 1.06 – 1.21 0.000116 1066 10669 all phecode
281.11 Pernicious anemia Hematopoietic 1.14 1.06 – 1.23 0.000672 750 7514 all phecode
281.12 Other vitamin B12 deficiency anemia Hematopoietic 1.02 0.882 – 1.19 0.764 177 1769 all phecode
281.13 Folate-deficiency anemia Hematopoietic 1.18 1.01 – 1.37 0.0353 183 1836 all phecode
281.9 Deficiency anemias Hematopoietic 1.38 1.03 – 1.84 0.0299 54 538 all phecode
282 Hereditary hemolytic anemias Hematopoietic 1.17 0.984 – 1.38 0.0752 150 1499 all phecode
282.8 Other hemoglobinopathies Hematopoietic 1.11 0.853 – 1.44 0.444 56 560 all phecode
282.9 Other hereditary hemolytic anemias Hematopoietic 1.2 0.957 – 1.5 0.116 85 849 all phecode
283 Acquired hemolytic anemias Hematopoietic 1.04 0.871 – 1.25 0.647 135 1377 all phecode
283.1 Autoimmune hemolytic anemias Hematopoietic 1.04 0.846 – 1.27 0.726 103 1059 all phecode
284 Aplastic anemia Hematopoietic 1.12 1.02 – 1.24 0.0218 435 4357 all phecode
285 Other anemias Hematopoietic 1.07 1.05 – 1.09 4.46e-11 12104 121094 all phecode
285.1 Acute posthemorrhagic anemia Hematopoietic 1.11 0.979 – 1.26 0.105 271 2707 all phecode
285.2 Anemia of chronic disease Hematopoietic 1.15 1.06 – 1.24 0.000669 697 6980 all phecode
285.22 Anemia in neoplastic disease Hematopoietic 1.09 0.984 – 1.2 0.101 414 4147 all phecode
286 Coagulation defects Hematopoietic 1.09 1.02 – 1.17 0.013 921 9218 all phecode
286.1 Congenital coagulation defects Hematopoietic 1.1 0.995 – 1.21 0.0636 459 4594 all phecode
286.11 Von willebrand's disease Hematopoietic 1.13 0.919 – 1.38 0.251 96 959 all phecode
286.12
Congenital deficiency of other clotting factors
Congenital deficiency of other clotting factors (including factor VII)
 Hematopoietic 1.13 1 – 1.27 0.0485 294 2944 all phecode
286.13 Congenital factor VIII disorder Hematopoietic 1.03 0.796 – 1.33 0.827 63 630 all phecode
286.5
Hemorrhagic disorder due to intrinsic
Hemorrhagic disorder due to intrinsic circulating anticoagulants
 Hematopoietic 1.33 1.06 – 1.65 0.0126 86 860 all phecode
286.7 Other and unspecified coagulation defects Hematopoietic 1.08 0.975 – 1.2 0.134 386 3867 all phecode
287 Purpura and other hemorrhagic conditions Hematopoietic 1.03 0.983 – 1.09 0.194 1652 16532 all phecode
287.1 Spontaneous ecchymoses Hematopoietic 1.04 0.861 – 1.25 0.704 129 1290 all phecode
287.2 Allergic purpura Hematopoietic 0.953 0.723 – 1.26 0.735 51 510 all phecode
287.3 Thrombocytopenia Hematopoietic 1.04 0.983 – 1.09 0.185 1553 15543 all phecode
287.31 Primary thrombocytopenia Hematopoietic 0.964 0.871 – 1.07 0.482 419 4195 all phecode
287.32 Secondary thrombocytopenia Hematopoietic 0.921 0.719 – 1.18 0.516 75 749 all phecode
288 Diseases of white blood cells Hematopoietic 1.01 0.975 – 1.04 0.639 3765 37672 all phecode
288.1 Decreased white blood cell count Hematopoietic 1 0.967 – 1.04 0.887 3168 31704 all phecode
288.11 Neutropenia Hematopoietic 1 0.967 – 1.04 0.874 3176 31784 all phecode
288.3 Eosinophilia Hematopoietic 0.817 0.643 – 1.04 0.0992 71 709 all phecode
289 Other diseases of blood and blood-forming organs Hematopoietic 1.11 1.03 – 1.19 0.00463 862 8625 all phecode
289.3
Personal history of diseases of blood and
Personal history of diseases of blood and blood-forming organs
 Hematopoietic 1.03 0.916 – 1.16 0.611 290 2897 all phecode
289.4 Lymphadenitis Hematopoietic 1.14 1.09 – 1.19 3.66e-10 2602 26061 all phecode
289.5 Diseases of spleen Hematopoietic 1.01 0.918 – 1.1 0.899 516 5153 all phecode
289.8 Polycythemia, secondary Hematopoietic 1.24 1.1 – 1.4 0.000396 292 2917 all phecode
289.9 Abnormality of red blood cells Hematopoietic 1.27 1.02 – 1.59 0.0363 90 900 all phecode
290
Delirium dementia and amnestic and other
Delirium dementia and amnestic and other cognitive disorders
 Mental Disorders 1.09 1.04 – 1.14 0.000453 1929 19281 all phecode
290.1 Dementias Mental Disorders 1.03 0.966 – 1.1 0.36 1004 10032 all phecode
290.11 Alzheimer's disease Mental Disorders 0.992 0.9 – 1.09 0.873 431 4307 all phecode
290.16 Vascular dementia Mental Disorders 1.08 0.937 – 1.24 0.296 201 2008 all phecode
290.2 Delirium due to conditions classified elsewhere Mental Disorders 1.12 1.03 – 1.21 0.00758 650 6501 all phecode
290.3
Other persistent mental disorders due to
Other persistent mental disorders due to conditions classified elsewhere
 Mental Disorders 1.74 1.35 – 2.24 1.91e-05 70 709 all phecode
291
Other specified nonpsychotic and/or transient
Other specified nonpsychotic and/or transient mental disorders
 Mental Disorders 1.15 1.07 – 1.24 0.000108 836 8385 all phecode
291.1
Transient mental disorders due to conditions
Transient mental disorders due to conditions classified elsewhere
 Mental Disorders 1.07 0.897 – 1.28 0.446 132 1320 all phecode
291.4
Specific nonpsychotic mental disorders due to
Specific nonpsychotic mental disorders due to brain damage
 Mental Disorders 1.13 1 – 1.28 0.046 286 2867 all phecode
291.8 Alteration of consciousness Mental Disorders 1.17 1.06 – 1.29 0.00175 436 4376 all phecode
292 Neurological disorders Mental Disorders 1.08 1.05 – 1.12 1.32e-07 4621 46260 all phecode
292.1 Aphasia/speech disturbance Mental Disorders 1.08 1.03 – 1.14 0.00357 1504 15074 all phecode
292.2 Mild cognitive impairment Mental Disorders 1.07 0.924 – 1.25 0.352 190 1907 all phecode
292.3 Memory loss Mental Disorders 1.06 0.98 – 1.15 0.147 696 6978 all phecode
292.4 Altered mental status Mental Disorders 1.09 1.05 – 1.14 6.72e-05 2181 21827 all phecode
292.6 Hallucinations Mental Disorders 1.09 0.969 – 1.22 0.154 307 3073 all phecode
293 Symptoms involving head and neck Mental Disorders 1.13 1.08 – 1.18 9.73e-08 2078 20779 all phecode
293.1
Swelling, mass, or lump in head and neck
Swelling, mass, or lump in head and neck [Space-occupying lesion, intracranial NOS]
 Mental Disorders 1.16 1.08 – 1.24 3.45e-05 901 9010 all phecode
295 Schizophrenia and other psychotic disorders Mental Disorders 1.22 1.14 – 1.31 3.56e-08 841 8446 all phecode
295.1 Schizophrenia Mental Disorders 1.22 1.12 – 1.33 5.17e-06 574 5766 all phecode
295.2 Paranoid disorders Mental Disorders 1.26 1.08 – 1.47 0.00327 178 1780 all phecode
295.3 Psychosis Mental Disorders 1.07 0.909 – 1.26 0.418 169 1710 all phecode
296 Mood disorders Mental Disorders 1.24 1.21 – 1.26 2.41e-109 12372 123822 all phecode
296.1 Bipolar Mental Disorders 1.16 1.09 – 1.24 6.3e-06 1059 10599 all phecode
296.2 Depression Mental Disorders 1.24 1.22 – 1.26 3.38e-108 11737 117469 all phecode
296.22 Major depressive disorder Mental Disorders 1.12 1 – 1.25 0.0405 361 3604 all phecode
297.2 Suicide or self-inflicted injury Mental Disorders 1.41 1.25 – 1.59 1.7e-08 311 3070 all phecode
300 Anxiety disorders Mental Disorders 1.15 1.13 – 1.18 1.79e-29 6844 68484 all phecode
300.1 Anxiety disorder Mental Disorders 1.16 1.13 – 1.19 1.95e-28 6324 63282 all phecode
300.11 Generalized anxiety disorder Mental Disorders 0.975 0.827 – 1.15 0.766 149 1499 all phecode
300.12 Agorophobia, social phobia, and panic disorder Mental Disorders 1.16 1.07 – 1.25 0.000278 707 7065 all phecode
300.13 Phobia Mental Disorders 1.22 1.11 – 1.34 2.2e-05 501 5013 all phecode
300.3 Obsessive-compulsive disorders Mental Disorders 0.979 0.823 – 1.16 0.806 140 1407 all phecode
300.4 Dysthymic disorder Mental Disorders 1.1 0.827 – 1.46 0.52 53 530 all phecode
300.8 Acute reaction to stress Mental Disorders 1.22 1.01 – 1.46 0.037 124 1238 all phecode
300.9 Posttraumatic stress disorder Mental Disorders 1.27 1.05 – 1.53 0.0124 113 1129 all phecode
301 Personality disorders Mental Disorders 1.31 1.17 – 1.47 2.95e-06 334 3338 all phecode
301.2 Antisocial/borderline personality disorder Mental Disorders 1.29 1.07 – 1.57 0.0086 119 1186 all phecode
302 Sexual and gender identity disorders Mental Disorders 1.26 1.11 – 1.42 0.000331 283 2845 all phecode
303 Psychogenic and somatoform disorders Mental Disorders 1.1 1 – 1.21 0.0425 467 4679 all phecode
303.3 Psychogenic disorder Mental Disorders 1.09 0.975 – 1.21 0.131 350 3510 all phecode
303.4 Somatoform disorder Mental Disorders 1.12 0.929 – 1.35 0.234 123 1229 all phecode
304 Adjustment reaction Mental Disorders 1.29 1.14 – 1.45 3.32e-05 293 2936 all phecode
305.2 Eating disorder Mental Disorders 0.898 0.719 – 1.12 0.344 90 900 all phecode
306 Other mental disorder Mental Disorders 1.63 1.61 – 1.65 2.92e-1187 28056 230087 all phecode
306.9 Tension headache Mental Disorders 1.17 1.04 – 1.31 0.0078 315 3148 all phecode
313 Pervasive developmental disorders Mental Disorders 1.01 0.801 – 1.28 0.925 76 770 all phecode
313.3 Autism Mental Disorders 1.07 0.817 – 1.41 0.617 53 539 all phecode
315 Develomental delays and disorders Mental Disorders 1.12 1 – 1.25 0.0439 351 3517 all phecode
315.1 Learning disorder Mental Disorders 1.05 0.898 – 1.23 0.536 161 1610 all phecode
315.2 Speech and language disorder Mental Disorders 1.22 0.978 – 1.52 0.0777 88 880 all phecode
316 Substance addiction and disorders Mental Disorders 1.43 1.39 – 1.47 2.01e-131 5313 53131 all phecode
316.1 Polyneuropathy due to drugs Mental Disorders 1.17 0.903 – 1.51 0.234 60 599 all phecode
317 Alcohol-related disorders Mental Disorders 1.3 1.27 – 1.32 1.59e-167 12696 126892 all phecode
317.1 Alcoholism Mental Disorders 1.26 1.23 – 1.29 5.72e-93 8890 88923 all phecode
317.11 Alcoholic liver damage Mental Disorders 1.45 1.35 – 1.56 1.25e-23 838 8392 all phecode
318 Tobacco use disorder Mental Disorders 1.81 1.78 – 1.84 7.7e-1216 19359 185465 all phecode
320 Meningitis Neurological 1.08 0.978 – 1.19 0.131 444 4447 all phecode
323 Encephalitis Neurological 1.05 0.934 – 1.17 0.44 342 3422 all phecode
323.2 Acute (transverse) myelitis Neurological 0.989 0.781 – 1.25 0.927 74 739 all phecode
324 Other CNS infection and poliomyelitis Neurological 0.928 0.823 – 1.05 0.224 292 2916 all phecode
327 Sleep disorders Neurological 1.12 1.05 – 1.19 0.000227 1164 11659 all phecode
327.3 Sleep apnea Neurological 1.18 1.14 – 1.21 1.08e-24 4428 44318 all phecode
327.4 Insomnia Neurological 1.14 0.97 – 1.33 0.115 163 1660 all phecode
327.41 Organic or persistent insomnia Neurological 1.12 0.946 – 1.33 0.187 136 1390 all phecode
331 Other cerebral degenerations Neurological 1.14 1.08 – 1.22 1.15e-05 1142 11416 all phecode
331.1 Hydrocephalus Neurological 1.14 1.04 – 1.25 0.00449 502 5014 all phecode
331.9 Cerebral degeneration, unspecified Neurological 1.17 1.06 – 1.3 0.00131 430 4298 all phecode
332 Parkinson's disease Neurological 0.911 0.857 – 0.968 0.00277 1126 11254 all phecode
333
Extrapyramidal disease and abnormal movement
Extrapyramidal disease and abnormal movement disorders
 Neurological 1.09 1.02 – 1.17 0.0105 894 8954 all phecode
333.1 Essential tremor Neurological 1.13 0.983 – 1.3 0.0847 216 2157 all phecode
333.2 Myoclonus Neurological 1.17 0.95 – 1.44 0.139 96 958 all phecode
333.4 Torsion dystonia Neurological 1.03 0.9 – 1.17 0.702 253 2528 all phecode
334 Degenerative disease of the spinal cord Neurological 1.11 1.05 – 1.16 3.86e-05 1812 18130 all phecode
334.1 Spinocerebellar disease Neurological 0.938 0.778 – 1.13 0.497 117 1169 all phecode
334.2 Anterior horn cell disease Neurological 0.932 0.818 – 1.06 0.293 245 2446 all phecode
335 Multiple sclerosis Neurological 1.08 1.02 – 1.15 0.00647 1340 13385 all phecode
337 Disorders of the autonomic nervous system Neurological 1.15 1.02 – 1.31 0.0225 266 2668 all phecode
337.1 Peripheral autonomic neuropathy Neurological 1.25 0.994 – 1.58 0.0565 72 719 all phecode
338 Pain Neurological 1.2 1.11 – 1.29 2.61e-06 768 7692 all phecode
338.1 Acute pain Neurological 1.17 1.05 – 1.3 0.00407 394 3937 all phecode
338.2 Chronic pain Neurological 1.25 1.12 – 1.39 3.49e-05 380 3817 all phecode
339 Other headache syndromes Neurological 1.12 1.1 – 1.15 4.68e-22 7819 78241 all phecode
340 Migraine Neurological 1.06 1.02 – 1.11 0.00175 2860 28602 all phecode
340.1 Migrain with aura Neurological 1.11 0.965 – 1.29 0.141 212 2117 all phecode
341
Other demyelinating diseases of central nervous
Other demyelinating diseases of central nervous system
 Neurological 1.2 1.05 – 1.37 0.00783 252 2535 all phecode
342 Hemiplegia Neurological 1.14 1.08 – 1.2 1.6e-06 1494 14947 all phecode
343 Infantile cerebral palsy Neurological 0.843 0.71 – 1 0.0522 145 1450 all phecode
344 Other paralytic syndromes Neurological 1.13 1.04 – 1.23 0.00294 658 6593 all phecode
345 Epilepsy, recurrent seizures, convulsions Neurological 1.11 1.08 – 1.14 3.68e-12 5023 50270 all phecode
345.1 Epilepsy Neurological 1.09 1.01 – 1.17 0.0209 866 8661 all phecode
345.11 Generalized convulsive epilepsy Neurological 1.08 0.982 – 1.2 0.111 439 4385 all phecode
345.12 Partial epilepsy Neurological 1.04 0.922 – 1.18 0.504 277 2776 all phecode
345.3 Convulsions Neurological 1.06 1.01 – 1.1 0.0126 2235 22339 all phecode
346.1
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of skull and head
 Neurological 1.07 0.902 – 1.28 0.426 144 1438 all phecode
348 Other conditions of brain Neurological 1.16 1.07 – 1.24 0.000131 778 7808 all phecode
348.2 Cerebral edema and compression of brain Neurological 1.23 1.08 – 1.39 0.00168 268 2678 all phecode
348.4 Cerebral cysts Neurological 0.915 0.761 – 1.1 0.344 133 1350 all phecode
348.7 Coma Neurological 1.03 0.923 – 1.15 0.612 358 3596 all phecode
348.8 Encephalopathy, not elsewhere classified Neurological 1.14 0.998 – 1.29 0.054 249 2504 all phecode
348.9 Other conditions of brain, NOS Neurological 1.05 0.945 – 1.16 0.385 390 3899 all phecode
349
Other and unspecified disorders of the nervous
Other and unspecified disorders of the nervous system
 Neurological 1.18 1.05 – 1.31 0.00403 342 3414 all phecode
350 Abnormal movement Neurological 1.12 1.08 – 1.17 1.99e-08 2671 26722 all phecode
350.1 Abnormal involuntary movements Neurological 1.15 1.08 – 1.24 5.46e-05 887 8852 all phecode
350.2 Abnormality of gait Neurological 1.11 1.06 – 1.17 6.16e-05 1596 15969 all phecode
350.3 Lack of coordination Neurological 1.04 0.934 – 1.16 0.475 363 3638 all phecode
350.6 Disturbances of sensation of smell and taste Neurological 1.11 0.852 – 1.45 0.433 54 540 all phecode
351 Other peripheral nerve disorders Neurological 1.15 1.13 – 1.17 3.64e-50 12420 124321 all phecode
352 Disorders of other cranial nerves Neurological 1.09 1.03 – 1.15 0.00373 1370 13706 all phecode
352.1 Trigeminal nerve disorders [CN5] Neurological 1.09 0.994 – 1.21 0.0651 463 4638 all phecode
352.2 Facial nerve disorders [CN7] Neurological 1.1 1.02 – 1.18 0.00953 880 8795 all phecode
353 Nerve root and plexus disorders Neurological 1.19 1.12 – 1.27 2.47e-08 1131 11319 all phecode
353.1 Nerve plexus lesions Neurological 1.14 0.948 – 1.38 0.162 114 1138 all phecode
353.2 Nerve root lesions Neurological 1.33 1.01 – 1.74 0.0392 57 570 all phecode
356 Hereditary and idiopathic peripheral neuropathy Neurological 1.26 1.06 – 1.49 0.009 152 1520 all phecode
357 Inflammatory and toxic neuropathy Neurological 1.11 1.05 – 1.18 0.000142 1361 13648 all phecode
358 Myoneural disorders Neurological 1.08 0.943 – 1.25 0.257 211 2109 all phecode
358.1 Myasthenia gravis Neurological 1.07 0.924 – 1.24 0.365 192 1919 all phecode
359 Muscular dystrophies and other myopathies Neurological 1.05 0.958 – 1.16 0.284 465 4646 all phecode
359.1 Muscular dystrophies Neurological 1.07 0.895 – 1.29 0.443 122 1219 all phecode
359.2 Myopathy Neurological 1.06 0.955 – 1.18 0.262 360 3597 all phecode
360 Disorders of the globe Sense Organs 0.952 0.85 – 1.07 0.388 337 3367 all phecode
360.2 Progressive myopia Sense Organs 0.872 0.766 – 0.991 0.0365 251 2508 all phecode
361 Retinal detachments and defects Sense Organs 0.943 0.909 – 0.978 0.00144 3246 32453 all phecode
361.1 Retinal detachment with retinal defect Sense Organs 0.942 0.891 – 0.996 0.0346 1389 13884 all phecode
361.2 Retinoschisis and retinal cysts Sense Organs 0.841 0.658 – 1.07 0.166 68 680 all phecode
362 Other retinal disorders Sense Organs 1.03 0.997 – 1.07 0.078 3836 38370 all phecode
362.2
Degeneration of macula and posterior pole of
Degeneration of macula and posterior pole of retina
 Sense Organs 1.04 0.994 – 1.09 0.0901 2182 21813 all phecode
362.29 Macular degeneration (senile) of retina NOS Sense Organs 1.04 0.993 – 1.08 0.099 2179 21783 all phecode
362.3 Other nondiabetic retinopathy Sense Organs 0.967 0.821 – 1.14 0.685 161 1609 all phecode
362.31 Separation of retinal layers Sense Organs 0.925 0.752 – 1.14 0.464 99 990 all phecode
362.4 Retinal vascular changes and abnomalities Sense Organs 1.06 0.99 – 1.14 0.095 848 8477 all phecode
362.6 Peripheral retinal degenerations Sense Organs 0.93 0.798 – 1.08 0.351 182 1827 all phecode
362.7 Hereditary retinal dystrophies Sense Organs 0.94 0.75 – 1.18 0.589 82 812 all phecode
362.8 Retinal hemorrhage/ischemia Sense Organs 1.26 1.03 – 1.53 0.0219 116 1159 all phecode
363
Chorioretinal inflammations, scars, and other
Chorioretinal inflammations, scars, and other disorders of choroid
 Sense Organs 0.888 0.758 – 1.04 0.144 170 1699 all phecode
363.3 Chorioretinal scars Sense Organs 0.769 0.597 – 0.989 0.0409 69 690 all phecode
364 Corneal opacity and other disorders of cornea Sense Organs 0.93 0.858 – 1.01 0.0786 647 6485 all phecode
364.1 Corneal opacity Sense Organs 1.09 0.879 – 1.34 0.447 90 910 all phecode
364.2 Corneal edema Sense Organs 0.927 0.741 – 1.16 0.51 79 800 all phecode
364.4 Corneal degenerations Sense Organs 0.878 0.758 – 1.02 0.083 201 2017 all phecode
364.41 Keratoconus Sense Organs 0.767 0.611 – 0.961 0.0214 86 869 all phecode
364.5 Corneal dystrophy Sense Organs 1.01 0.875 – 1.16 0.913 211 2109 all phecode
364.9 Cornea replaced by transplant Sense Organs 0.959 0.785 – 1.17 0.683 100 1000 all phecode
365 Glaucoma Sense Organs 0.983 0.953 – 1.01 0.282 4408 44136 all phecode
365.1 Open-angle glaucoma Sense Organs 0.907 0.851 – 0.968 0.00331 1032 10346 all phecode
365.11 Primary open angle glaucoma Sense Organs 0.905 0.848 – 0.966 0.00266 1026 10287 all phecode
365.2 Primary angle-closure glaucoma Sense Organs 1.02 0.942 – 1.1 0.648 698 6996 all phecode
366 Cataract Sense Organs 1.04 1.03 – 1.06 7.03e-09 19926 168711 all phecode
366.1 Nonsenile Cataract Sense Organs 1.09 0.855 – 1.4 0.477 69 700 all phecode
366.2 Senile cataract Sense Organs 1.06 1.04 – 1.09 3.56e-07 8231 81909 all phecode
366.3 Traumatic cataract Sense Organs 0.918 0.755 – 1.12 0.39 102 1019 all phecode
367
Disorders of refraction and accommodation
Disorders of refraction and accommodation; blindness and low vision
 Sense Organs 1.02 0.981 – 1.07 0.282 2408 24092 all phecode
367.1 Myopia Sense Organs 0.959 0.904 – 1.02 0.157 1251 12519 all phecode
367.2 Astigmatism Sense Organs 1.08 0.928 – 1.25 0.329 190 1899 all phecode
367.8 Hypermetropia Sense Organs 1.13 0.989 – 1.28 0.0725 253 2530 all phecode
367.9 Blindness and low vision Sense Organs 1.11 1.02 – 1.2 0.00982 719 7198 all phecode
368 Visual disturbances Sense Organs 1.06 1.02 – 1.1 0.00201 2962 29648 all phecode
368.1 Amblyopia Sense Organs 1.02 0.933 – 1.11 0.672 532 5322 all phecode
368.2 Diplopia and disorders of binocular vision Sense Organs 1.11 1.03 – 1.2 0.00893 727 7288 all phecode
368.3 Anisometropia Sense Organs 0.983 0.832 – 1.16 0.836 154 1548 all phecode
368.4 Visual field defects Sense Organs 1.05 0.938 – 1.17 0.405 333 3327 all phecode
368.9 Subjective visual disturbances Sense Organs 1.08 0.99 – 1.17 0.0847 612 6115 all phecode
369 Infection of the eye Sense Organs 0.98 0.897 – 1.07 0.662 553 5544 all phecode
369.2 Eye infection, viral Sense Organs 0.83 0.689 – 1 0.0514 125 1257 all phecode
369.5 Conjunctivitis, infectious Sense Organs 0.943 0.816 – 1.09 0.431 213 2128 all phecode
370 Keratitis Sense Organs 1.03 0.907 – 1.16 0.683 286 2855 all phecode
370.1 Corneal ulcer Sense Organs 1.03 0.867 – 1.23 0.707 141 1408 all phecode
371 Inflammation of the eye Sense Organs 1 0.966 – 1.04 0.887 3045 30480 all phecode
371.1 Uveitis, noninfectious or NOS Sense Organs 1.03 0.936 – 1.13 0.573 482 4821 all phecode
371.3 Inflammation of eyelids Sense Organs 0.989 0.948 – 1.03 0.61 2353 23555 all phecode
372 Disorders of conjunctiva Sense Organs 1.08 1 – 1.16 0.0411 760 7602 all phecode
374 Other disorders of eyelids Sense Organs 1.06 1.03 – 1.08 0.00012 5680 56807 all phecode
374.1 Ectropion or entropion Sense Organs 1.08 1.01 – 1.15 0.0174 1063 10645 all phecode
374.3 Ptosis of eyelid Sense Organs 1.06 1.01 – 1.12 0.0128 1825 18232 all phecode
375 Disorders of lacrimal system Sense Organs 1.06 1.02 – 1.11 0.00856 2204 22031 all phecode
375.2 Epiphora Sense Organs 1.04 0.97 – 1.11 0.272 898 8969 all phecode
376 Disorders of the orbit Sense Organs 1.09 0.871 – 1.37 0.446 86 859 all phecode
377 Disorders of optic nerve and visual pathways Sense Organs 1.02 0.917 – 1.14 0.687 361 3618 all phecode
377.1 Optic atrophy Sense Organs 0.93 0.702 – 1.23 0.614 56 570 all phecode
377.3 Optic neuritis/neuropathy Sense Organs 1.12 0.929 – 1.36 0.229 125 1249 all phecode
378
Strabismus and other disorders of binocular eye
Strabismus and other disorders of binocular eye movements
 Sense Organs 1.05 0.997 – 1.11 0.0634 1410 14116 all phecode
378.1 Strabismus (not specified as paralytic) Sense Organs 1.07 0.998 – 1.14 0.0556 909 9082 all phecode
378.2 Nystagmus and other irregular eye movements Sense Organs 1.03 0.893 – 1.18 0.708 213 2138 all phecode
378.5 Paralytic strabismus Sense Organs 1.07 0.95 – 1.22 0.254 275 2755 all phecode
379 Other disorders of eye Sense Organs 1.02 0.99 – 1.06 0.161 3703 37063 all phecode
379.2 Disorders of vitreous body Sense Organs 0.952 0.901 – 1.01 0.084 1367 13665 all phecode
379.3 Aphakia and other disorders of lens Sense Organs 1.07 1.02 – 1.12 0.00811 1813 18134 all phecode
379.4 Anomalies of pupillary function Sense Organs 0.975 0.766 – 1.24 0.836 71 710 all phecode
379.5 Disorders of iris and ciliary body Sense Organs 1.1 0.992 – 1.22 0.0707 400 4028 all phecode
379.9 Pain, swelling or discharge of eye Sense Organs 1.13 0.967 – 1.33 0.122 169 1690 all phecode
380 Disorders of external ear Sense Organs 1.2 1.1 – 1.3 1.35e-05 642 6413 all phecode
380.1 Otitis externa Sense Organs 1.16 1.06 – 1.27 0.0013 509 5107 all phecode
380.4 Impacted cerumen Sense Organs 0.987 0.883 – 1.1 0.813 362 3614 all phecode
381 Otitis media and Eustachian tube disorders Sense Organs 1.12 1.07 – 1.17 5.03e-07 2150 21493 all phecode
381.1 Otitis media Sense Organs 1.11 1.06 – 1.17 3.94e-05 1767 17668 all phecode
381.11 Suppurative and unspecified otitis media Sense Organs 1.2 1.11 – 1.29 8.15e-07 852 8524 all phecode
381.2 Eustachian tube disorders Sense Organs 1.15 0.992 – 1.34 0.064 193 1929 all phecode
381.3 Mastoiditis & related conditions Sense Organs 1.06 0.904 – 1.24 0.47 171 1709 all phecode
381.9 Otorrhea Sense Organs 1.21 1.07 – 1.36 0.00279 281 2807 all phecode
382 Otalgia Sense Organs 1.06 0.945 – 1.19 0.317 308 3084 all phecode
383 Otosclerosis Sense Organs 0.976 0.87 – 1.1 0.685 309 3090 all phecode
384 Other disorders of tympanic membrane Sense Organs 1.18 1.11 – 1.25 3.07e-08 1299 12991 all phecode
384.4 Perforation of tympanic membrane Sense Organs 1.18 1.11 – 1.26 4.11e-07 1043 10432 all phecode
385 Other disorders of middle ear and mastoid Sense Organs 1.11 1.03 – 1.19 0.00543 783 7837 all phecode
385.3 Cholesteatoma Sense Organs 1.1 1.01 – 1.2 0.0274 607 6078 all phecode
385.5
Tympanosclerosis and middle ear disease related
Tympanosclerosis and middle ear disease related to otitis media
 Sense Organs 1.12 0.982 – 1.28 0.0908 241 2409 all phecode
386
Vertiginous syndromes and other disorders of
Vertiginous syndromes and other disorders of vestibular system
 Sense Organs 1.05 0.996 – 1.1 0.0705 1736 17373 all phecode
386.1 Meniere's disease Sense Organs 1.04 0.957 – 1.14 0.334 576 5768 all phecode
386.2 Peripheral or central vertigo Sense Organs 1.01 0.909 – 1.12 0.864 377 3763 all phecode
386.3 Labyrinthitis Sense Organs 1.05 0.976 – 1.13 0.185 765 7664 all phecode
386.9
Dizziness and giddiness (Light-headedness and
Dizziness and giddiness (Light-headedness and vertigo)
 Sense Organs 1.08 1.04 – 1.11 1.86e-06 4582 45806 all phecode
388 Other disorders of ear Sense Organs 1.07 0.927 – 1.24 0.349 202 2017 all phecode
389 Hearing loss Sense Organs 1.09 1.06 – 1.13 7.11e-08 4188 41944 all phecode
389.1 Sensorineural hearing loss Sense Organs 1.05 0.952 – 1.15 0.34 456 4553 all phecode
389.2 Conductive hearing loss Sense Organs 1.1 0.999 – 1.21 0.0516 450 4497 all phecode
389.4 Tinnitus Sense Organs 1.07 0.974 – 1.17 0.163 513 5134 all phecode
394 Rheumatic disease of the heart valves Circulatory System 1.1 1.07 – 1.13 1.69e-10 4899 48974 all phecode
394.2 Mitral valve disease Circulatory System 1.08 1.04 – 1.12 5.87e-05 2993 29922 all phecode
394.3 Aortic valve disease Circulatory System 1.08 1.02 – 1.14 0.00936 1282 12814 all phecode
394.7 Disease of tricuspid valve Circulatory System 1.12 1.05 – 1.19 0.000525 1058 10566 all phecode
395 Heart valve disorders Circulatory System 1.09 1.06 – 1.13 2.93e-08 4223 42219 all phecode
395.1 Nonrheumatic mitral valve disorders Circulatory System 1.09 1.04 – 1.13 2.87e-05 2891 28900 all phecode
395.2 Nonrheumatic aortic valve disorders Circulatory System 1.17 1.03 – 1.32 0.0127 276 2766 all phecode
395.3 Nonrheumatic tricuspid valve disorders Circulatory System 1.12 0.909 – 1.37 0.297 105 1039 all phecode
395.4 Nonrheumatic pulmonary valve disorders Circulatory System 1.26 1.03 – 1.55 0.0275 97 970 all phecode
395.6 Heart valve replaced Circulatory System 1.07 1.02 – 1.13 0.0106 1495 14942 all phecode
396 Abnormal heart sounds Circulatory System 1.01 0.948 – 1.08 0.764 1048 10468 all phecode
401 Hypertension Circulatory System 1.13 1.12 – 1.14 1.31e-165 73956 266957 all phecode
401.1 Essential hypertension Circulatory System 1.13 1.12 – 1.14 1.85e-164 73731 266739 all phecode
401.2 Hypertensive heart and/or renal disease Circulatory System 1.17 1.12 – 1.23 6.31e-11 1898 19031 all phecode
401.21 Hypertensive heart disease Circulatory System 1.21 1.09 – 1.35 0.000395 370 3699 all phecode
401.22 Hypertensive chronic kidney disease Circulatory System 1.16 1.1 – 1.22 1.59e-08 1543 15483 all phecode
401.3 Other hypertensive complications Circulatory System 1.41 1.2 – 1.67 5.36e-05 144 1438 all phecode
402
Elevated blood pressure reading without
Elevated blood pressure reading without diagnosis of hypertension
 Circulatory System 1.13 1.07 – 1.19 1.12e-05 1479 14786 all phecode
411 Ischemic Heart Disease Circulatory System 1.18 1.16 – 1.19 1.5e-153 31245 210714 all phecode
411.1 Unstable angina (intermediate coronary syndrome) Circulatory System 1.23 1.2 – 1.27 2.81e-46 5152 51498 all phecode
411.2 Myocardial infarction Circulatory System 1.23 1.21 – 1.25 1.25e-100 11950 112699 all phecode
411.3 Angina pectoris Circulatory System 1.19 1.17 – 1.21 2.71e-96 15888 143745 all phecode
411.4 Coronary atherosclerosis Circulatory System 1.18 1.16 – 1.19 1.05e-102 20171 154621 all phecode
411.41 Aneurysm and dissection of heart Circulatory System 1.06 0.984 – 1.15 0.123 700 6997 all phecode
411.8
Other chronic ischemic heart disease
Other chronic ischemic heart disease, unspecified
 Circulatory System 1.23 1.21 – 1.25 6.19e-128 15290 131798 all phecode
411.9
Other acute and subacute forms of ischemic
Other acute and subacute forms of ischemic heart disease
 Circulatory System 1.19 1.12 – 1.26 8.92e-09 1218 12166 all phecode
414 Other forms of chronic heart disease Circulatory System 1.23 1.18 – 1.29 6.51e-18 1823 18228 all phecode
414.2 ASCVD Circulatory System 1.57 1.23 – 2.01 0.000336 72 719 all phecode
415 Pulmonary heart disease Circulatory System 1.1 1.06 – 1.13 7.76e-09 4476 44810 all phecode
415.11 Pulmonary embolism and infarction, acute Circulatory System 0.905 0.725 – 1.13 0.381 75 750 all phecode
415.2 Chronic pulmonary heart disease Circulatory System 1.15 1.05 – 1.24 0.0014 601 6002 all phecode
415.21 Primary pulmonary hypertension Circulatory System 1.14 1.03 – 1.25 0.00984 448 4475 all phecode
416 Cardiomegaly Circulatory System 1.11 1.07 – 1.16 8.66e-08 2680 26793 all phecode
418 Nonspecific chest pain Circulatory System 1.14 1.12 – 1.15 9.23e-93 28599 270106 all phecode
418.1 Precordial pain Circulatory System 1.13 1.09 – 1.16 2.15e-11 3551 35541 all phecode
420 Carditis Circulatory System 1.06 1.01 – 1.11 0.0154 2106 21053 all phecode
420.1 Myocarditis Circulatory System 1.39 1.15 – 1.67 0.00049 127 1267 all phecode
420.2 Pericarditis Circulatory System 1.05 0.994 – 1.11 0.0824 1338 13371 all phecode
420.21 Acute pericarditis Circulatory System 1.14 0.996 – 1.31 0.0568 223 2227 all phecode
420.22 Chronic pericarditis Circulatory System 1.17 0.969 – 1.42 0.101 113 1129 all phecode
420.3 Endocarditis Circulatory System 1.04 0.963 – 1.12 0.321 719 7194 all phecode
425 Cardiomyopathy Circulatory System 1.1 1.04 – 1.17 0.00112 1271 12699 all phecode
425.1 Primary/intrinsic cardiomyopathies Circulatory System 1.1 1.04 – 1.16 0.00179 1236 12349 all phecode
425.11 Hypertrophic obstructive cardiomyopathy Circulatory System 0.948 0.797 – 1.13 0.546 133 1329 all phecode
425.12 Other hypertrophic cardiomyopathy Circulatory System 1.09 0.926 – 1.29 0.295 163 1629 all phecode
425.8 Other cardiomyopathy Circulatory System 1.11 0.859 – 1.43 0.426 60 600 all phecode
426 Cardiac conduction disorders Circulatory System 1.12 1.09 – 1.14 5.13e-18 6910 69146 all phecode
426.2 Atrioventricular [AV] block Circulatory System 1.1 1.06 – 1.16 1.08e-05 2114 21162 all phecode
426.21 First degree AV block Circulatory System 1.07 1.01 – 1.15 0.0308 986 9867 all phecode
426.23 Second degree AV block Circulatory System 1.09 0.992 – 1.2 0.0725 452 4515 all phecode
426.24 Atrioventricular block, complete Circulatory System 1.09 1.01 – 1.19 0.0365 587 5868 all phecode
426.25 Other heart block Circulatory System 1.28 1.07 – 1.54 0.00714 131 1318 all phecode
426.3 Bundle branch block Circulatory System 1.12 1.08 – 1.16 1.61e-09 3336 33359 all phecode
426.31 Right bundle branch block Circulatory System 1.1 1.04 – 1.16 0.000536 1494 14933 all phecode
426.32 Left bundle branch block Circulatory System 1.13 1.07 – 1.18 1.58e-06 1750 17503 all phecode
426.4 Anomalous atrioventricular excitation Circulatory System 1.25 1.09 – 1.43 0.00115 233 2328 all phecode
426.8 Other cardiac conduction disorders Circulatory System 1.13 0.874 – 1.47 0.345 60 600 all phecode
426.9 Cardiac pacemaker/device in situ Circulatory System 1.14 1.1 – 1.19 1.96e-10 2475 24774 all phecode
426.91 Cardiac pacemaker in situ Circulatory System 1.13 1.09 – 1.18 1.22e-08 2274 22762 all phecode
427 Cardiac dysrhythmias Circulatory System 1.09 1.08 – 1.11 3.23e-40 24207 206016 all phecode
427.1 Paroxysmal tachycardia, unspecified Circulatory System 1.12 1.08 – 1.16 2.95e-09 3199 32017 all phecode
427.11 Paroxysmal supraventricular tachycardia Circulatory System 1.13 1.08 – 1.18 2.24e-08 2344 23474 all phecode
427.12 Paroxysmal ventricular tachycardia Circulatory System 1.08 1.01 – 1.16 0.0187 936 9365 all phecode
427.2 Atrial fibrillation and flutter Circulatory System 1.09 1.08 – 1.11 3.96e-25 14628 133501 all phecode
427.3 Other specified cardiac dysrhythmias Circulatory System 1.05 1.01 – 1.09 0.00762 3228 32281 all phecode
427.4 Cardiac arrest and ventricular fibrillation Circulatory System 1.2 1.13 – 1.27 1.56e-09 1193 11915 all phecode
427.41 Ventricular fibrillation and flutter Circulatory System 1.11 0.991 – 1.24 0.0726 344 3437 all phecode
427.42 Cardiac arrest Circulatory System 1.23 1.15 – 1.31 7.73e-10 990 9890 all phecode
427.5 Arrhythmia (cardiac) NOS Circulatory System 1.14 1.07 – 1.22 8.95e-05 952 9541 all phecode
427.6 Premature beats Circulatory System 1 0.919 – 1.1 0.916 535 5358 all phecode
427.61 Supraventricular premature beats Circulatory System 0.941 0.783 – 1.13 0.52 117 1168 all phecode
427.7 Tachycardia NOS Circulatory System 1.14 1.09 – 1.19 1.09e-08 2185 21865 all phecode
427.8 Sinoatrial node dysfunction (Bradycardia) Circulatory System 1.1 0.992 – 1.22 0.0699 402 4029 all phecode
427.9 Palpitations Circulatory System 1.08 1.05 – 1.12 5.02e-06 3811 38105 all phecode
428 Congestive heart failure; nonhypertensive Circulatory System 1.19 1.16 – 1.23 3.48e-36 5605 56018 all phecode
428.1 Congestive heart failure (CHF) NOS Circulatory System 1.22 1.17 – 1.28 7.82e-19 2111 21108 all phecode
428.2 Heart failure NOS Circulatory System 1.19 1.16 – 1.23 8.3e-30 4455 44524 all phecode
429
Ill-defined descriptions and complications of
Ill-defined descriptions and complications of heart disease
 Circulatory System 1.08 0.996 – 1.16 0.0625 716 7168 all phecode
429.1 Heart transplant/surgery Circulatory System 1.19 0.925 – 1.53 0.176 64 639 all phecode
429.2 Abnormal function study of cardiovascular system Circulatory System 1.07 0.975 – 1.17 0.157 522 5211 all phecode
429.3 Symptoms involving cardiovascular system Circulatory System 1.14 0.981 – 1.32 0.0895 196 1978 all phecode
430 Intracranial hemorrhage Circulatory System 1.15 1.09 – 1.2 1.11e-08 1883 18825 all phecode
430.1 Subarachnoid hemorrhage Circulatory System 1.2 1.12 – 1.29 4.15e-07 836 8353 all phecode
430.2 Intracerebral hemorrhage Circulatory System 1.13 1.05 – 1.22 0.0015 765 7656 all phecode
430.3 Subdural hemorrhage Circulatory System 0.993 0.877 – 1.12 0.913 267 2667 all phecode
433 Cerebrovascular disease Circulatory System 1.15 1.12 – 1.18 3e-35 8749 87456 all phecode
433.1 Occlusion and stenosis of precerebral arteries Circulatory System 1.33 1.25 – 1.41 9.48e-21 1185 11825 all phecode
433.12 Cerebral atherosclerosis Circulatory System 1.14 0.996 – 1.3 0.0576 227 2267 all phecode
433.2 Occlusion of cerebral arteries Circulatory System 1.12 1.08 – 1.15 4.31e-12 4233 42320 all phecode
433.21
Cerebral artery occlusion, with cerebral
Cerebral artery occlusion, with cerebral infarction
 Circulatory System 1.12 1.06 – 1.17 1.68e-05 1680 16794 all phecode
433.3 Cerebral ischemia Circulatory System 1.14 1.09 – 1.18 4.48e-11 2895 28989 all phecode
433.31 Transient cerebral ischemia Circulatory System 1.12 1.07 – 1.17 8.22e-07 2135 21379 all phecode
433.5 Cerebral aneurysm Circulatory System 1.27 1.15 – 1.41 6.27e-06 394 3939 all phecode
433.8 Late effects of cerebrovascular disease Circulatory System 1.19 1.12 – 1.26 4.25e-09 1279 12783 all phecode
440 Atherosclerosis Circulatory System 1.48 1.4 – 1.56 1.18e-41 1380 13822 all phecode
440.1 Atherosclerosis of renal artery Circulatory System 1.27 1.04 – 1.55 0.0174 113 1129 all phecode
440.2 Atherosclerosis of the extremities Circulatory System 1.61 1.49 – 1.73 2.37e-36 805 8070 all phecode
440.9 Atherosclerosis of aorta Circulatory System 1.45 1.28 – 1.64 5.68e-09 287 2867 all phecode
441 Vascular insufficiency of intestine Circulatory System 1.17 1.08 – 1.27 0.000241 614 6154 all phecode
441.1 Acute vascular insufficiency of intestine Circulatory System 1.14 1.01 – 1.29 0.0373 283 2827 all phecode
442 Other aneurysm Circulatory System 1.24 1.18 – 1.3 6.95e-19 1892 18959 all phecode
442.1 Aortic aneurysm Circulatory System 1.26 1.19 – 1.33 3.95e-17 1458 14625 all phecode
442.11 Abdominal aortic aneurysm Circulatory System 1.45 1.36 – 1.56 6.56e-27 931 9341 all phecode
442.2 Aneurysm of iliac artery Circulatory System 1.36 1.11 – 1.67 0.00328 102 1019 all phecode
442.3 Aneurysm of artery of lower extremity Circulatory System 1.24 1.05 – 1.46 0.0109 169 1696 all phecode
442.4 Arterial dissection Circulatory System 1.12 0.849 – 1.47 0.426 54 549 all phecode
442.8 Aneurysm of other specified artery Circulatory System 1.03 0.895 – 1.19 0.653 203 2028 all phecode
443 Peripheral vascular disease Circulatory System 1.32 1.28 – 1.37 2.39e-62 3921 39273 all phecode
443.1 Raynaud's syndrome Circulatory System 1.11 1.05 – 1.18 0.000556 1145 11438 all phecode
443.7
Peripheral angiopathy in diseases classified
Peripheral angiopathy in diseases classified elsewhere
 Circulatory System 1.2 1.08 – 1.33 0.000602 384 3878 all phecode
443.8 Other specified peripheral vascular diseases Circulatory System 1.34 1.3 – 1.39 2.03e-64 3686 36906 all phecode
443.9 Peripheral vascular disease, unspecified Circulatory System 1.46 1.4 – 1.52 1.38e-72 2579 25846 all phecode
444 Arterial embolism and thrombosis Circulatory System 1.49 1.39 – 1.59 3.99e-30 922 9251 all phecode
444.1
Arterial embolism and thrombosis of lower
Arterial embolism and thrombosis of lower extremity artery
 Circulatory System 1.54 1.41 – 1.68 4.74e-22 554 5552 all phecode
446 Polyarteritis nodosa and allied conditions Circulatory System 1.05 0.977 – 1.13 0.186 822 8226 all phecode
446.4 Wegener's granulomatosis Circulatory System 1.12 0.969 – 1.3 0.124 188 1878 all phecode
446.5 Giant cell arteritis Circulatory System 1.01 0.913 – 1.12 0.804 388 3879 all phecode
446.9 Arteritis NOS Circulatory System 1.02 0.895 – 1.17 0.723 239 2400 all phecode
447 Other disorders of arteries and arterioles Circulatory System 1.46 1.38 – 1.54 6.18e-38 1327 13316 all phecode
447.1 Stricture of artery Circulatory System 1.6 1.48 – 1.71 3.29e-37 868 8712 all phecode
448 Disease of capillaries Circulatory System 1.1 0.925 – 1.3 0.287 142 1420 all phecode
450 Noninfectious disorders of lymphatic channels Circulatory System 1.13 1.05 – 1.23 0.00154 704 7034 all phecode
451 Phlebitis and thrombophlebitis Circulatory System 1.08 1.04 – 1.11 9.85e-06 3955 39683 all phecode
451.2
Phlebitis and thrombophlebitis of lower
Phlebitis and thrombophlebitis of lower extremities
 Circulatory System 1.07 1.04 – 1.11 7.9e-05 3683 36977 all phecode
452 Other venous embolism and thrombosis Circulatory System 1.14 1.04 – 1.24 0.00346 564 5645 all phecode
454 Varicose veins Circulatory System 1.08 1.06 – 1.1 1.25e-14 11180 112047 all phecode
454.1 Varicose veins of lower extremity Circulatory System 1.08 1.06 – 1.1 1.97e-14 11503 115272 all phecode
454.11 Varicose veins of lower extremity, symptomtic Circulatory System 1.14 1.05 – 1.24 0.00205 624 6325 all phecode
455 Hemorrhoids Circulatory System 1.07 1.05 – 1.08 2.71e-20 23452 234585 all phecode
456 Chronic venous insufficiency [CVI] Circulatory System 1.1 0.951 – 1.28 0.194 184 1868 all phecode
457
Encounter for long-term (current) use of
Encounter for long-term (current) use of anticoagulants, antithrombotics, aspirin
 Circulatory System 0.862 0.703 – 1.06 0.152 97 967 all phecode
458 Hypotension Circulatory System 1.09 1.06 – 1.12 8.97e-11 5769 57772 all phecode
458.1 Orthostatic hypotension Circulatory System 1.04 0.986 – 1.1 0.143 1335 13376 all phecode
458.2 Iatrogenic hypotension Circulatory System 1.17 1.02 – 1.34 0.0206 235 2348 all phecode
458.9 Hypotension NOS Circulatory System 1.11 1.07 – 1.15 4.56e-09 3494 35005 all phecode
459 Other disorders of circulatory system Circulatory System 1.15 1.13 – 1.17 6.33e-66 16268 160790 all phecode
459.1 Hemorrhage NOS Circulatory System 1.16 0.977 – 1.38 0.0897 142 1420 all phecode
459.9 Circulatory disease NEC Circulatory System 1.15 1.13 – 1.17 7.37e-65 16103 159422 all phecode
464 Acute sinusitis Respiratory 1.31 1.13 – 1.52 0.000292 196 1957 all phecode
465
Acute upper respiratory infections of multiple
Acute upper respiratory infections of multiple or unspecified sites
 Respiratory 1.05 1.01 – 1.1 0.0187 2283 22827 all phecode
465.2 Acute pharyngitis Respiratory 1.03 0.961 – 1.11 0.394 835 8348 all phecode
465.4 Acute laryngitis and tracheitis Respiratory 0.983 0.835 – 1.16 0.838 165 1649 all phecode
470 Septal Deviations/Turbinate Hypertrophy Respiratory 1.1 1.07 – 1.14 1.07e-10 4654 46553 all phecode
471 Nasal polyps Respiratory 1.05 1.01 – 1.09 0.00647 3297 32973 all phecode
472 Chronic pharyngitis and nasopharyngitis Respiratory 1.01 0.941 – 1.07 0.875 960 9594 all phecode
473 Diseases of the larynx and vocal cords Respiratory 1.24 1.19 – 1.29 3.68e-24 2554 25548 all phecode
473.1 Chronic laryngitis Respiratory 1.54 1.24 – 1.9 8.19e-05 104 1038 all phecode
473.3 Paralysis/spasm of vocal cords or larynx Respiratory 1.07 0.942 – 1.21 0.308 264 2647 all phecode
473.4 Voice disturbance Respiratory 1.2 1.12 – 1.27 2.24e-08 1080 10789 all phecode
474 Acute and chronic tonsillitis Respiratory 1.08 1.03 – 1.14 0.00189 1772 17710 all phecode
474.1 Acute tonsillitis Respiratory 1.12 1.02 – 1.22 0.0144 549 5486 all phecode
474.2 Chronic tonsillitis and adenoiditis Respiratory 1.07 1.01 – 1.14 0.0305 1122 11199 all phecode
475 Chronic sinusitis Respiratory 1.09 1.05 – 1.14 2.16e-05 2589 25882 all phecode
476 Allergic rhinitis Respiratory 0.95 0.891 – 1.01 0.116 1055 10563 all phecode
477 Epistaxis or throat hemorrhage Respiratory 1.06 1.01 – 1.1 0.00982 2447 24452 all phecode
478 Throat pain Respiratory 1.12 1 – 1.24 0.0403 377 3789 all phecode
479 Other upper respiratory disease Respiratory 1.13 1.09 – 1.17 1.2e-13 4074 40737 all phecode
480 Pneumonia Respiratory 1.19 1.17 – 1.22 3.11e-65 10336 103397 all phecode
480.1 Bacterial pneumonia Respiratory 1.19 1.16 – 1.22 1.53e-42 6637 66410 all phecode
480.11 Pneumococcal pneumonia Respiratory 1.2 1.17 – 1.23 1.62e-39 5883 58863 all phecode
480.12 Pseudomonal pneumonia Respiratory 1.38 1.11 – 1.7 0.00316 93 929 all phecode
480.2 Viral pneumonia Respiratory 1.03 0.811 – 1.31 0.803 72 720 all phecode
480.3 Pneumonia due to fungus (mycoses) Respiratory 1.29 1.06 – 1.58 0.0128 99 989 all phecode
480.5 Bronchopneumonia and lung abscess Respiratory 1.26 1.17 – 1.36 4.37e-10 794 7951 all phecode
481 Influenza Respiratory 1.2 1.07 – 1.35 0.00145 328 3278 all phecode
483 Acute bronchitis and bronchiolitis Respiratory 1.33 1.15 – 1.54 0.000141 193 1930 all phecode
495 Asthma Respiratory 1.12 1.11 – 1.14 1.39e-69 25689 250406 all phecode
495.2 Asthma with exacerbation Respiratory 1.33 1.17 – 1.52 1.45e-05 250 2510 all phecode
496 Chronic airway obstruction Respiratory 1.5 1.47 – 1.53 9.41e-327 10424 101546 all phecode
496.1 Emphysema Respiratory 1.6 1.52 – 1.69 6.47e-76 1743 17438 all phecode
496.2 Chronic bronchitis Respiratory 1.68 1.61 – 1.75 1.13e-149 2947 29498 all phecode
496.21 Obstructive chronic bronchitis Respiratory 1.71 1.64 – 1.78 3.28e-146 2706 27081 all phecode
496.3 Bronchiectasis Respiratory 1.16 1.11 – 1.22 4.93e-10 1885 18859 all phecode
497 Bronchitis Respiratory 1.24 1.14 – 1.34 4.98e-07 626 6267 all phecode
500 Lung disease due to external agents Respiratory 1.39 1.25 – 1.54 8.01e-10 412 4099 all phecode
500.1 Extrinsic allergic alveolitis Respiratory 1.25 0.997 – 1.57 0.0527 79 784 all phecode
500.2 Pneumoconiosis Respiratory 1.46 1.27 – 1.67 8.57e-08 243 2409 all phecode
501 Pneumonitis due to inhalation of food or vomitus Respiratory 1.14 1.05 – 1.24 0.00139 656 6557 all phecode
502 Postinflammatory pulmonary fibrosis Respiratory 1.24 1.16 – 1.33 5.88e-10 917 9193 all phecode
503 Pulmonary congestion and hypostasis Respiratory 1.35 1.23 – 1.48 1.02e-10 508 5079 all phecode
504 Other alveolar and parietoalveolar pneumonopathy Respiratory 1.25 1.12 – 1.4 9.58e-05 328 3280 all phecode
505 Other pulmonary inflamation or edema Respiratory 1.08 0.832 – 1.41 0.556 61 610 all phecode
506 Empyema and pneumothorax Respiratory 1.23 1.16 – 1.31 1.51e-11 1133 11362 all phecode
507 Pleurisy; pleural effusion Respiratory 1.13 1.1 – 1.16 2.43e-21 6419 64252 all phecode
508
Pulmonary collapse; interstitial and
Pulmonary collapse; interstitial and compensatory emphysema
 Respiratory 1.19 1.13 – 1.24 4.96e-13 1996 19947 all phecode
509 Respiratory failure, insufficiency, arrest Respiratory 1.26 1.21 – 1.32 6.51e-30 2599 26031 all phecode
509.1 Respiratory failure Respiratory 1.3 1.24 – 1.36 2.59e-30 2068 20708 all phecode
509.2 Respiratory insufficiency Respiratory 1.31 1.25 – 1.37 1.2e-27 1806 18106 all phecode
509.5 Respiratory arrest Respiratory 1.08 0.912 – 1.27 0.378 143 1429 all phecode
509.8
Dependence on respirator [Ventilator] or
Dependence on respirator [Ventilator] or supplemental oxygen
 Respiratory 1.17 1.05 – 1.29 0.00397 386 3863 all phecode
510 Other diseases of lung Respiratory 1.26 1.17 – 1.35 2.58e-09 755 7554 all phecode
512 Other symptoms of respiratory system Respiratory 1.16 1.14 – 1.19 6.59e-43 9031 90349 all phecode
512.1 Wheezing Respiratory 1.26 1.09 – 1.45 0.00136 220 2196 all phecode
512.2 Painful respiration Respiratory 1.09 0.949 – 1.26 0.215 207 2075 all phecode
512.7 Shortness of breath Respiratory 1.2 1.17 – 1.24 9.62e-41 5842 58498 all phecode
512.8 Cough Respiratory 1.12 1.08 – 1.16 9.74e-09 2866 28642 all phecode
512.9 Other dyspnea Respiratory 1.14 1.07 – 1.22 0.000115 914 9124 all phecode
513 Respiratory abnormalities Respiratory 1.07 0.985 – 1.16 0.111 611 6112 all phecode
513.3 Hypoventilation Respiratory 1.17 0.936 – 1.46 0.168 83 830 all phecode
513.4 Hyperventilation Respiratory 1.06 0.94 – 1.2 0.33 278 2778 all phecode
513.8 Disorders of diaphragm Respiratory 1.05 0.892 – 1.25 0.538 153 1538 all phecode
514 Abnormal findings examination of lungs Respiratory 1.29 1.24 – 1.35 2.51e-33 2465 24673 all phecode
516 Abnormal sputum Respiratory 1.3 1.25 – 1.36 6.93e-31 2132 21335 all phecode
516.1 Hemoptysis Respiratory 1.3 1.24 – 1.36 2.33e-29 2073 20745 all phecode
519
Other diseases of respiratory system, not
Other diseases of respiratory system, not elsewhere classified
 Respiratory 1.16 1.13 – 1.18 1.65e-41 9366 93681 all phecode
519.2 Respiratory complications Respiratory 1.36 1.21 – 1.52 1.36e-07 327 3279 all phecode
519.8 Other diseases of respiratory system, NEC Respiratory 1.16 1.14 – 1.19 6.88e-42 8853 88522 all phecode
519.9
Symptoms involving respiratory system and other
Symptoms involving respiratory system and other chest symptoms
 Respiratory 0.945 0.84 – 1.06 0.342 303 3049 all phecode
520 Disorders of tooth development Digestive 0.997 0.952 – 1.04 0.886 2038 20354 all phecode
520.1 Hereditary disturbances in tooth structure Digestive 1.03 0.774 – 1.36 0.85 53 530 all phecode
520.2 Disturbances in tooth eruption Digestive 0.972 0.931 – 1.01 0.185 2356 23539 all phecode
521 Diseases of hard tissues of teeth Digestive 1.07 1.03 – 1.11 0.000498 3016 30245 all phecode
521.1 Dental caries Digestive 1.07 1.03 – 1.11 0.000434 3026 30353 all phecode
522 Diseases of pulp and periapical tissues Digestive 1.13 1.07 – 1.18 1.75e-06 1774 17750 all phecode
522.5 Periapical abscess Digestive 1.11 1.04 – 1.18 0.000778 1172 11731 all phecode
523 Gingival and periodontal diseases Digestive 1.1 1.04 – 1.15 0.000435 1681 16812 all phecode
523.1 Gingivitis Digestive 1.13 0.927 – 1.37 0.229 113 1127 all phecode
523.3 Periodontitis (acute or chronic) Digestive 1.06 1 – 1.13 0.0467 1165 11650 all phecode
523.31 Acute periodontitis Digestive 1.09 1 – 1.18 0.0457 666 6667 all phecode
523.32 Chronic periodontitis Digestive 1.02 0.936 – 1.12 0.627 560 5594 all phecode
524 Dentofacial anomalies, including malocclusion Digestive 1 0.894 – 1.12 0.968 331 3307 all phecode
524.3 Anomalies of tooth position/malocclusion Digestive 0.952 0.846 – 1.07 0.411 305 3046 all phecode
525
Other diseases of the teeth and supporting
Other diseases of the teeth and supporting structures
 Digestive 1.12 1.07 – 1.16 6.16e-08 2668 26728 all phecode
525.2 Atrophy of edentulous alveolar ridge Digestive 1.14 0.895 – 1.45 0.291 72 720 all phecode
526 Diseases of the jaws Digestive 1.06 0.986 – 1.13 0.118 928 9279 all phecode
526.1 Cysts of the jaws Digestive 1.01 0.897 – 1.13 0.931 329 3289 all phecode
526.3 Anomalies of jaw size/symmetry Digestive 0.893 0.69 – 1.15 0.387 61 610 all phecode
526.4 Temporomandibular joint disorders Digestive 1.16 1.02 – 1.32 0.0291 240 2406 all phecode
526.41 Temporomandibular joint disorder, unspecified Digestive 1.15 1.01 – 1.32 0.0378 233 2336 all phecode
526.5 Inflammatory conditions of jaw Digestive 1.09 0.887 – 1.33 0.421 110 1098 all phecode
526.9 Jaw disease NOS Digestive 1.05 0.919 – 1.2 0.467 233 2329 all phecode
527 Diseases of the salivary glands Digestive 1.2 1.11 – 1.3 4.1e-06 694 6943 all phecode
527.1 Hypertrophy of salivary gland Digestive 1.17 0.942 – 1.46 0.153 84 838 all phecode
527.2 Sialoadenitis Digestive 1.21 1.09 – 1.35 0.000429 365 3656 all phecode
527.7 Disturbance of salivary secretion Digestive 1.23 0.953 – 1.58 0.113 62 619 all phecode
527.8 Other specified diseases of the salivary glands Digestive 1.25 1.04 – 1.51 0.0187 120 1200 all phecode
528
Diseases of the oral soft tissues, excluding
Diseases of the oral soft tissues, excluding lesions specific for gingiva and tongue
 Digestive 1.14 1.1 – 1.18 1.3e-14 3873 38741 all phecode
528.1 Stomatitis and mucositis Digestive 1.08 0.978 – 1.18 0.132 468 4675 all phecode
528.11 Stomatitis and mucositis (ulcerative) Digestive 1.1 0.993 – 1.22 0.0685 389 3884 all phecode
528.12 Oral aphthae Digestive 0.962 0.773 – 1.2 0.726 84 840 all phecode
528.3 Cellulitis and abscess of oral soft tissues Digestive 1.22 1.04 – 1.42 0.0133 179 1790 all phecode
528.4 Cysts of oral soft tissues Digestive 1.22 1.01 – 1.49 0.0408 122 1219 all phecode
528.41 Cyst of the salivary gland Digestive 1.06 0.853 – 1.32 0.587 94 940 all phecode
528.5 Diseases of lips Digestive 1.1 1.02 – 1.19 0.0182 681 6813 all phecode
528.6 Leukoplakia of oral mucosa Digestive 1.22 1.09 – 1.37 0.000585 308 3079 all phecode
528.7 Sialolithiasis Digestive 1.21 1.07 – 1.36 0.00147 314 3138 all phecode
529 Diseases and other conditions of the tongue Digestive 1.12 1.05 – 1.18 0.000249 1232 12312 all phecode
529.1 Glossitis Digestive 1.13 1 – 1.28 0.0436 299 2986 all phecode
530 Diseases of esophagus Digestive 1.13 1.12 – 1.15 7.11e-102 33453 279172 all phecode
530.1 Esophagitis, GERD and related diseases Digestive 1.13 1.12 – 1.15 4.5e-97 31253 272429 all phecode
530.11 GERD Digestive 1.13 1.12 – 1.15 1.22e-70 22633 225879 all phecode
530.12 Ulcer of esophagus Digestive 1.15 1.11 – 1.18 1.48e-20 5203 52068 all phecode
530.14 Reflux esophagitis Digestive 1.13 1.1 – 1.15 8.48e-31 10444 104493 all phecode
530.2 Esophageal bleeding (varices/hemorrhage) Digestive 1.14 1.09 – 1.2 1.6e-07 1681 16808 all phecode
530.3 Stricture and stenosis of esophagus Digestive 1.09 1.04 – 1.14 0.000293 1869 18684 all phecode
530.5 Disorders of esophageal motility Digestive 1.11 1.03 – 1.21 0.0101 635 6365 all phecode
530.6 Diverticulum of esophagus, acquired Digestive 1.09 0.921 – 1.29 0.316 153 1527 all phecode
530.7 Gastroesophageal laceration-hemorrhage syndrome Digestive 1.16 1.04 – 1.29 0.0094 341 3416 all phecode
530.9 Heartburn Digestive 1.13 1.08 – 1.19 4.42e-08 2087 20881 all phecode
531 Peptic ulcer (excl. esophageal) Digestive 1.19 1.16 – 1.22 3.03e-43 7103 71066 all phecode
531.1 Hemorrhage from gastrointestinal ulcer Digestive 1.1 1.02 – 1.2 0.0171 637 6374 all phecode
531.2 Gastric ulcer Digestive 1.18 1.14 – 1.22 5.68e-24 4091 40941 all phecode
531.3 Duodenal ulcer Digestive 1.21 1.17 – 1.26 9.5e-24 2999 30005 all phecode
531.4 Peptic ulcer, site unspecified Digestive 1.29 1.17 – 1.43 5.94e-07 427 4268 all phecode
532 Dysphagia Digestive 1.13 1.1 – 1.16 6.52e-20 6427 64329 all phecode
535 Gastritis and duodenitis Digestive 1.14 1.12 – 1.15 1.38e-89 28078 261548 all phecode
535.1 Acute gastritis Digestive 1.14 1.08 – 1.21 1.36e-05 1183 11833 all phecode
535.2 Atrophic gastritis Digestive 1.04 0.938 – 1.16 0.425 370 3687 all phecode
535.6 Duodenitis Digestive 1.19 1.16 – 1.22 1.05e-46 7592 75928 all phecode
535.8 Other specified gastritis Digestive 1.13 1.11 – 1.16 7.66e-27 8071 80763 all phecode
535.9 Gastritis and duodenitis, NOS Digestive 1.11 0.925 – 1.34 0.257 120 1191 all phecode
536.8
Dyspepsia and other specified disorders of
Dyspepsia and other specified disorders of function of stomach
 Digestive 1.1 0.974 – 1.25 0.122 259 2576 all phecode
537 Other disorders of stomach and duodenum Digestive 1.15 1.11 – 1.19 8.17e-15 3391 33907 all phecode
540 Appendiceal conditions Digestive 1.03 0.994 – 1.07 0.102 3088 30890 all phecode
540.1 Appendicitis Digestive 1.04 0.997 – 1.08 0.0689 2895 28963 all phecode
540.11 Acute appendicitis Digestive 1.02 0.978 – 1.06 0.383 2601 26019 all phecode
550 Abdominal hernia Digestive 1.08 1.07 – 1.09 2.44e-46 45429 282640 all phecode
550.1 Inguinal hernia Digestive 1.01 0.99 – 1.02 0.461 15794 123247 all phecode
550.2 Diaphragmatic hernia Digestive 1.1 1.09 – 1.11 7.7e-49 26494 238953 all phecode
550.3 Femoral hernia Digestive 1.04 0.959 – 1.13 0.346 651 6504 all phecode
550.4 Umbilical hernia Digestive 1.12 1.09 – 1.16 1.01e-11 3705 37072 all phecode
550.5 Ventral hernia Digestive 1.16 1.12 – 1.2 6.02e-17 3435 34338 all phecode
555
Inflammatory bowel disease and other
Inflammatory bowel disease and other gastroenteritis and colitis
 Digestive 1.14 1.1 – 1.17 5.74e-16 4444 44442 all phecode
555.1 Regional enteritis Digestive 1.17 1.11 – 1.23 7.44e-10 1734 17340 all phecode
555.2 Ulcerative colitis Digestive 1.11 1.07 – 1.15 3.2e-08 3178 31786 all phecode
555.21 Ulcerative colitis (chronic) Digestive 1.13 1.04 – 1.24 0.00532 538 5382 all phecode
556 Ulceration of the lower GI tract Digestive 1.16 1.09 – 1.24 5.22e-06 1055 10592 all phecode
556.1 Ulceration of intestine Digestive 1.23 1.14 – 1.34 3.18e-07 670 6714 all phecode
557 Intestinal malabsorption (non-celiac) Digestive 0.986 0.877 – 1.11 0.811 299 2987 all phecode
557.1 Celiac disease Digestive 0.89 0.848 – 0.934 2.53e-06 1837 18388 all phecode
558 Noninfectious gastroenteritis Digestive 1.1 1.08 – 1.12 1.56e-27 15492 155105 all phecode
559 Ileostomy status Digestive 1.1 1.04 – 1.15 0.000349 1656 16541 all phecode
560 Intestinal obstruction without mention of hernia Digestive 1.07 1.03 – 1.1 1e-04 3936 39337 all phecode
560.1 Paralytic ileus Digestive 1.09 0.999 – 1.2 0.0538 523 5231 all phecode
560.2 Impaction of intestine Digestive 1.05 0.927 – 1.19 0.438 268 2671 all phecode
560.3 Peritoneal or intestinal adhesions Digestive 1.07 0.998 – 1.15 0.0557 832 8317 all phecode
560.4 Other intestinal obstruction Digestive 1.07 1.03 – 1.11 0.000184 3358 33550 all phecode
561 Symptoms involving digestive system Digestive 1.09 1.08 – 1.11 3.8e-26 15772 157686 all phecode
561.1 Diarrhea Digestive 1.14 1.03 – 1.25 0.00816 466 4653 all phecode
561.2 Flatulence Digestive 1.06 1.01 – 1.11 0.0252 1687 16859 all phecode
562 Diverticulosis and diverticulitis Digestive 1.11 1.09 – 1.12 4e-56 26714 211692 all phecode
562.1 Diverticulosis Digestive 1.11 1.09 – 1.12 4.12e-56 26672 211642 all phecode
563 Constipation Digestive 1.12 1.1 – 1.14 6.95e-27 10314 103140 all phecode
564 Functional digestive disorders Digestive 1.12 1.11 – 1.14 4.78e-59 21639 209949 all phecode
564.1 Irritable Bowel Syndrome Digestive 1.12 1.09 – 1.15 3.21e-15 5508 55117 all phecode
564.8
Abnormal findings on exam of gastrointestinal
Abnormal findings on exam of gastrointestinal tract/ abdominal area
 Digestive 1.08 1.02 – 1.13 0.00364 1645 16457 all phecode
564.9 Personal history of diseases of digestive system Digestive 1.13 1.12 – 1.15 2.05e-49 15186 151648 all phecode
565 Anal and rectal conditions Digestive 1.13 1.11 – 1.14 3.61e-42 14744 147535 all phecode
565.1 Anal and rectal polyp Digestive 1.16 1.14 – 1.19 1.28e-35 7351 73533 all phecode
567 Peritonitis and retroperitoneal infections Digestive 1.16 1.09 – 1.25 1.25e-05 929 9293 all phecode
568 Other disorders of peritoneum Digestive 1.12 1.08 – 1.16 1.35e-09 3262 32602 all phecode
568.1
Peritoneal adhesions (postoperative)
Peritoneal adhesions (postoperative) (postinfection)
 Digestive 1.12 1.08 – 1.16 1.94e-09 3101 30987 all phecode
569 Other disorders of intestine Digestive 1.11 1.07 – 1.15 1.78e-10 4192 41922 all phecode
569.1 Toxic gastroenteritis and colitis Digestive 1.06 0.889 – 1.26 0.529 148 1479 all phecode
569.2 Gastrointestinal complications Digestive 1.06 0.966 – 1.16 0.216 486 4868 all phecode
571 Chronic liver disease and cirrhosis Digestive 1.2 1.16 – 1.25 2.46e-21 2957 29628 all phecode
571.5 Other chronic nonalcoholic liver disease Digestive 1.2 1.14 – 1.26 4.32e-13 1689 16917 all phecode
571.51 Cirrhosis of liver without mention of alcohol Digestive 1.09 0.907 – 1.32 0.352 113 1139 all phecode
571.6 Primary biliary cirrhosis Digestive 1.24 1.09 – 1.41 0.00104 257 2568 all phecode
571.8
Liver abscess and sequelae of chronic liver
Liver abscess and sequelae of chronic liver disease
 Digestive 1.19 1.12 – 1.28 1.36e-07 976 9804 all phecode
571.81 Portal hypertension Digestive 1.23 1.12 – 1.35 7.03e-06 528 5285 all phecode
572 Ascites (non malignant) Digestive 1.06 1.01 – 1.12 0.0232 1544 15454 all phecode
573 Other disorders of liver Digestive 1.09 1.04 – 1.15 0.00123 1496 14982 all phecode
573.2 Liver replaced by transplant Digestive 1.04 0.845 – 1.28 0.702 96 960 all phecode
573.3 Hepatomegaly Digestive 1.26 1.12 – 1.42 0.000118 297 2968 all phecode
573.5 Jaundice (not of newborn) Digestive 1.05 0.975 – 1.12 0.209 896 8955 all phecode
573.7 Abnormal results of function study of liver Digestive 1.08 1.04 – 1.12 1.51e-05 3454 34597 all phecode
573.9 Abnormal serum enzyme levels Digestive 1.17 1.02 – 1.35 0.0289 209 2089 all phecode
574 Cholelithiasis and cholecystitis Digestive 1.1 1.08 – 1.12 1.68e-28 15607 156123 all phecode
574.1 Cholelithiasis Digestive 1.09 1.07 – 1.11 5.19e-22 13549 135537 all phecode
574.11 Cholelithiasis with acute cholecystitis Digestive 1.14 1.08 – 1.2 1.76e-06 1506 15072 all phecode
574.12 Cholelithiasis with other cholecystitis Digestive 1.08 1.05 – 1.11 2.14e-08 5429 54289 all phecode
574.2 Calculus of bile duct Digestive 1.14 1.1 – 1.19 1.56e-10 2620 26191 all phecode
574.3 Cholecystitis without cholelithiasis Digestive 1.13 1.09 – 1.18 4.75e-10 2748 27523 all phecode
575 Other biliary tract disease Digestive 1.1 1.07 – 1.14 9.04e-09 3867 38724 all phecode
575.1 Cholangitis Digestive 1.06 0.964 – 1.16 0.232 495 4945 all phecode
575.2 Obstruction of bile duct Digestive 1.13 1.05 – 1.22 0.000841 774 7756 all phecode
575.6 Cholesterolosis of gallbladder Digestive 1.03 0.936 – 1.14 0.526 458 4577 all phecode
575.7 Other disorders of gallbladder Digestive 1.06 1 – 1.12 0.0349 1408 14107 all phecode
575.8 Other disorders of biliary tract Digestive 1.16 1.09 – 1.24 3.92e-06 1036 10367 all phecode
575.9
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of biliary tract
 Digestive 1.22 1.1 – 1.36 0.000279 348 3488 all phecode
577 Diseases of pancreas Digestive 1.13 1.09 – 1.18 8.26e-10 2668 26677 all phecode
577.1 Acute pancreatitis Digestive 1.15 1.1 – 1.2 4.39e-09 1996 19962 all phecode
577.2 Chronic pancreatitis Digestive 1.3 1.19 – 1.42 1.22e-08 515 5149 all phecode
577.3 Cyst and pseudocyst of pancreas Digestive 1.13 1.01 – 1.25 0.0319 365 3650 all phecode
578 Gastrointestinal hemorrhage Digestive 1.09 1.07 – 1.11 5.3e-32 20626 206278 all phecode
578.1 Hematemesis Digestive 1.22 1.16 – 1.27 1.52e-16 1958 19564 all phecode
578.2 Blood in stool Digestive 1.15 1.1 – 1.19 2.61e-11 2626 26283 all phecode
578.8 Hemorrhage of rectum and anus Digestive 1.08 1.06 – 1.1 2.71e-16 13073 130745 all phecode
578.9 Hemorrhage of gastrointestinal tract Digestive 1.09 1.06 – 1.12 9.45e-09 5275 52787 all phecode
579 Other symptoms involving abdomen and pelvis Digestive 1.05 1 – 1.11 0.0461 1548 15498 all phecode
579.2 Splenomegaly Digestive 1.11 1 – 1.23 0.0411 422 4246 all phecode
579.8 Nonspecific abnormal findings in stool contents Digestive 1.02 0.973 – 1.08 0.371 1654 16540 all phecode
580 Nephritis; nephrosis; renal sclerosis Genitourinary 1.12 1.06 – 1.18 2.63e-05 1531 15350 all phecode
580.1 Glomerulonephritis Genitourinary 1.14 1.07 – 1.21 6.65e-05 1052 10544 all phecode
580.11 Proliferative glomerulonephritis Genitourinary 1.06 0.843 – 1.33 0.626 74 738 all phecode
580.12 Non-proliferative glomerulonephritis Genitourinary 1.04 0.872 – 1.24 0.661 135 1360 all phecode
580.14 Chronic glomerulonephritis, NOS Genitourinary 1.15 1.07 – 1.23 0.00011 876 8769 all phecode
580.2
Nephrotic syndrome without mention of
Nephrotic syndrome without mention of glomerulonephritis
 Genitourinary 1.06 0.967 – 1.17 0.207 468 4697 all phecode
580.3
Nephritis and nephropathy without mention of
Nephritis and nephropathy without mention of glomerulonephritis
 Genitourinary 1.19 1.04 – 1.36 0.00893 246 2460 all phecode
580.32
Nephritis and nephropathy with pathological
Nephritis and nephropathy with pathological lesion
 Genitourinary 1.16 1.02 – 1.32 0.0242 253 2529 all phecode
585 Renal failure Genitourinary 1.12 1.1 – 1.15 1.56e-20 6967 69751 all phecode
585.1 Acute renal failure Genitourinary 1.15 1.11 – 1.18 3.35e-18 4527 45305 all phecode
585.2 Renal failure NOS Genitourinary 1.1 1.05 – 1.17 0.00028 1460 14625 all phecode
585.3 Chronic renal failure [CKD] Genitourinary 1.14 1.09 – 1.18 2.62e-10 2644 26484 all phecode
585.31 Renal dialysis Genitourinary 1.16 1.06 – 1.27 0.00188 496 4955 all phecode
586 Other disorders of the kidney and ureters Genitourinary 1.1 1.06 – 1.14 6.3e-08 3355 33580 all phecode
586.1 Anatomical abnormatilies of kidney and ureters Genitourinary 1.22 1.06 – 1.41 0.00607 208 2089 all phecode
586.11 Small kidney Genitourinary 1.23 1.06 – 1.44 0.00755 179 1799 all phecode
586.2 Cyst of kidney, acquired Genitourinary 1.13 1.07 – 1.2 2.88e-05 1257 12582 all phecode
586.3 Vascular disorders of kidney/hypertrophy Genitourinary 1.2 0.952 – 1.51 0.123 80 799 all phecode
586.4 Stricture/obstruction of ureter Genitourinary 1.06 0.994 – 1.14 0.0752 910 9122 all phecode
587 Kidney replaced by transpant Genitourinary 1.03 0.929 – 1.15 0.536 368 3683 all phecode
588 Disorders resulting from impaired renal function Genitourinary 0.972 0.792 – 1.19 0.786 99 990 all phecode
589 Abnormal results of function study of kidney Genitourinary 1.1 0.913 – 1.32 0.321 116 1158 all phecode
590 Pyelonephritis Genitourinary 1.18 1.11 – 1.24 1.57e-08 1328 13285 all phecode
591 Urinary tract infection Genitourinary 1.09 1.07 – 1.11 2.92e-21 12400 123937 all phecode
592 Cystitis and urethritis Genitourinary 1.06 1.03 – 1.11 0.00116 2966 29661 all phecode
592.1 Cystitis Genitourinary 1.07 1.03 – 1.11 0.000431 2904 29035 all phecode
592.11 Acute cystitis Genitourinary 1.09 0.914 – 1.29 0.347 138 1372 all phecode
592.12 Chronic cystitis Genitourinary 1.05 0.984 – 1.13 0.132 889 8890 all phecode
592.13 Chronic interstitial cystitis Genitourinary 0.958 0.839 – 1.09 0.523 249 2486 all phecode
592.2 Urethritis and urethral syndrome Genitourinary 1.01 0.86 – 1.17 0.949 165 1662 all phecode
593 Hematuria Genitourinary 1.07 1.06 – 1.09 5.68e-18 16068 160204 all phecode
594 Urinary calculus Genitourinary 1.05 1.02 – 1.08 0.000247 6376 63761 all phecode
594.1 Calculus of kidney Genitourinary 1.06 1.02 – 1.1 0.00286 3175 31757 all phecode
594.2 Calculus of lower urinary tract Genitourinary 1 0.932 – 1.08 0.931 776 7764 all phecode
594.3 Calculus of ureter Genitourinary 1.07 1.03 – 1.12 0.00125 2401 24024 all phecode
594.8 Renal colic Genitourinary 1.04 0.994 – 1.09 0.0915 2050 20500 all phecode
595 Hydronephrosis Genitourinary 1.05 1 – 1.1 0.0361 1936 19395 all phecode
596 Other disorders of bladder Genitourinary 1.04 1.02 – 1.06 0.000737 9771 97778 all phecode
596.1 Bladder neck obstruction Genitourinary 0.987 0.942 – 1.03 0.579 1969 19690 all phecode
596.5 Functional disorders of bladder Genitourinary 1.08 1.02 – 1.13 0.00366 1658 16572 all phecode
597 Other disorders of urethra and urinary tract Genitourinary 1.04 1.01 – 1.08 0.0163 3913 39135 all phecode
597.1 Urethral stricture (not specified as infectious) Genitourinary 1.04 1.01 – 1.08 0.0201 3317 33137 all phecode
597.2 Urinary complications NEC Genitourinary 1.26 1 – 1.59 0.0495 78 778 all phecode
598 Abnormal findings on examination of urine Genitourinary 1.09 1.05 – 1.13 1.21e-06 3528 35302 all phecode
598.9
Other nonspecific findings on examination of
Other nonspecific findings on examination of urine
 Genitourinary 1.07 0.954 – 1.21 0.237 304 3035 all phecode
599 Other symptoms/disorders or the urinary system Genitourinary 1.07 1.06 – 1.09 2.14e-20 18428 184311 all phecode
599.1 Urinary obstruction Genitourinary 0.98 0.836 – 1.15 0.798 166 1670 all phecode
599.2 Retention of urine Genitourinary 1.05 1.02 – 1.07 0.000257 6718 67168 all phecode
599.3 Dysuria Genitourinary 1.11 1.05 – 1.18 0.000604 1196 11967 all phecode
599.4 Urinary incontinence Genitourinary 1.09 1.07 – 1.12 1.4e-14 8748 87477 all phecode
599.5 Frequency of urination and polyuria Genitourinary 1.05 1.02 – 1.09 0.00143 4018 40144 all phecode
599.6 Oliguria and anuria Genitourinary 1.11 0.91 – 1.36 0.302 105 1059 all phecode
599.8 Other symptoms involving urinary system Genitourinary 1.19 0.918 – 1.53 0.19 62 620 all phecode
599.9 Other abnormality of urination Genitourinary 1.05 1 – 1.1 0.0413 1913 19151 all phecode
600 Hyperplasia of prostate Genitourinary 1.01 0.993 – 1.03 0.21 11093 87892 all phecode
601 Inflammatory diseases of prostate Genitourinary 0.963 0.921 – 1.01 0.104 2081 20818 all phecode
601.1 Prostatitis Genitourinary 0.943 0.895 – 0.993 0.0262 1563 15644 all phecode
601.11 Acute prostatitis Genitourinary 0.897 0.785 – 1.02 0.107 234 2358 all phecode
601.12 Chronic prostatitis Genitourinary 0.948 0.886 – 1.01 0.116 910 9089 all phecode
601.3 Orchitis and epididymitis Genitourinary 1.28 0.982 – 1.66 0.0683 59 588 all phecode
601.4 Balanoposthitis Genitourinary 0.981 0.871 – 1.1 0.75 287 2864 all phecode
601.8
Other inflammatory disorders of male genital
Other inflammatory disorders of male genital organs
 Genitourinary 1.05 0.931 – 1.18 0.444 303 3019 all phecode
602 Other disorders of prostate Genitourinary 1.04 0.985 – 1.1 0.156 1341 13408 all phecode
603 Other disorders of testis Genitourinary 1.07 1.02 – 1.12 0.00366 2150 21512 all phecode
603.1 Hydrocele Genitourinary 1.04 0.988 – 1.1 0.124 1339 13402 all phecode
604 Disorders of penis Genitourinary 1.06 1.03 – 1.1 0.000601 3280 32779 all phecode
604.1 Redundant prepuce and phimosis/BXO Genitourinary 1.08 1.04 – 1.12 0.000174 2719 27172 all phecode
605 Erectile dysfunction [ED] Genitourinary 1.11 0.979 – 1.25 0.104 278 2800 all phecode
608 Other disorders of male genital organs Genitourinary 1.05 1.01 – 1.09 0.00904 2822 28236 all phecode
609 Male infertility and abnormal spermatozoa Genitourinary 1.15 1 – 1.32 0.0462 214 2138 all phecode
609.1 Infertility, male Genitourinary 0.967 0.752 – 1.24 0.793 63 638 all phecode
609.2 Abnormal spermatozoa Genitourinary 1.19 1.02 – 1.38 0.0313 169 1698 all phecode
610 Benign mammary dysplasias Genitourinary 1.07 1.02 – 1.11 0.0024 2482 24809 all phecode
610.1 Cystic mastopathy Genitourinary 0.993 0.928 – 1.06 0.84 925 9250 all phecode
610.2 Fibroadenosis of breast Genitourinary 1.03 0.918 – 1.16 0.595 306 3057 all phecode
610.3 Fibrosclerosis of breast Genitourinary 1.13 1 – 1.28 0.0454 302 3018 all phecode
610.4 Benign neoplasm of breast Genitourinary 1.06 1 – 1.12 0.0381 1388 13865 all phecode
610.8 Other specified benign mammary dysplasias Genitourinary 1.04 0.964 – 1.13 0.291 696 6954 all phecode
611 Abnormal findings on mammogram or breast exam Genitourinary 1.04 0.988 – 1.1 0.126 1574 15731 all phecode
611.1 Abnormal mammogram Genitourinary 1.39 1.06 – 1.82 0.0168 57 569 all phecode
611.3 Lump or mass in breast Genitourinary 1.04 0.984 – 1.1 0.171 1522 15213 all phecode
612
Breast conditions, congenital or relating to
Breast conditions, congenital or relating to hormones
 Genitourinary 1.11 1.03 – 1.19 0.00441 887 8871 all phecode
612.2 Hypertrophy of breast (Gynecomastia) Genitourinary 1.11 1.03 – 1.19 0.00374 849 8490 all phecode
612.3 Congenital anomalies of breast Genitourinary 1.1 0.863 – 1.39 0.449 72 719 all phecode
613 Other nonmalignant breast conditions Genitourinary 1.07 1.02 – 1.13 0.00745 1651 16519 all phecode
613.1 Inflammatory disease of breast Genitourinary 1.09 1.01 – 1.17 0.031 720 7210 all phecode
613.5 Mastodynia Genitourinary 0.991 0.787 – 1.25 0.941 77 768 all phecode
613.7 Other signs and symptoms in breast Genitourinary 1.01 0.931 – 1.09 0.865 702 7013 all phecode
613.8 Other specified disorders of breast Genitourinary 1.14 1.01 – 1.28 0.0277 327 3278 all phecode
613.9 Breast disorder NOS Genitourinary 0.988 0.856 – 1.14 0.865 207 2069 all phecode
614 Inflammatory diseases of female pelvic organs Genitourinary 1.05 1.03 – 1.08 0.000161 5711 57118 all phecode
614.1
Pelvic peritoneal adhesions, female
Pelvic peritoneal adhesions, female (postoperative) (postinfection)
 Genitourinary 1.05 1.01 – 1.1 0.0129 2538 25363 all phecode
614.3 Pelvic inflammatory disease (PID) Genitourinary 1.08 1.01 – 1.16 0.0326 830 8308 all phecode
614.31 Acute inflammatory pelvic disease Genitourinary 0.815 0.626 – 1.06 0.126 61 608 all phecode
614.32 Chronic inflammatory pelvic disease Genitourinary 1.09 0.983 – 1.2 0.105 422 4221 all phecode
614.33 Pelvic inflammatory disease, NOS Genitourinary 1.07 0.959 – 1.19 0.229 351 3510 all phecode
614.4 Inflammatory diseases of uterus, except cervix Genitourinary 1.08 0.957 – 1.23 0.207 277 2775 all phecode
614.5
Inflammatory disease of cervix, vagina, and
Inflammatory disease of cervix, vagina, and vulva
 Genitourinary 1.04 0.997 – 1.08 0.0705 2601 26023 all phecode
614.51 Cervicitis and endocervicitis Genitourinary 0.988 0.933 – 1.05 0.675 1318 13189 all phecode
614.52 Vaginitis and vulvovaginitis Genitourinary 1.07 0.965 – 1.18 0.206 428 4273 all phecode
614.53 Cyst or abscess of Bartholin's gland Genitourinary 1.07 0.99 – 1.15 0.0913 755 7574 all phecode
614.54 Abscess or ulceration of vulva Genitourinary 1.24 1.09 – 1.4 0.00083 274 2737 all phecode
615 Endometriosis Genitourinary 1.04 1 – 1.07 0.0307 4029 40284 all phecode
617
Disorders secondary to childbirth, surgery
Disorders secondary to childbirth, surgery, trauma
 Genitourinary 1.11 0.988 – 1.26 0.0767 304 3037 all phecode
618 Genital prolapse Genitourinary 1.03 1.01 – 1.05 0.00133 11689 116878 all phecode
618.1 Prolapse of vaginal walls Genitourinary 1.05 1.03 – 1.08 6.7e-05 7392 73940 all phecode
618.2 Uterine/Uterovaginal prolapse Genitourinary 1 0.975 – 1.03 0.854 5393 53918 all phecode
618.5 Prolapse of vaginal vault after hysterectomy Genitourinary 1.01 0.922 – 1.11 0.841 512 5125 all phecode
618.6 Vaginal enterocele, congenital or acquired Genitourinary 1.02 0.942 – 1.11 0.623 680 6794 all phecode
619 Noninflammatory female genital disorders Genitourinary 1.04 1.02 – 1.06 0.000429 8726 87297 all phecode
619.1
Noninflammatory disorders of ovary, fallopian
Noninflammatory disorders of ovary, fallopian tube, and broad ligament
 Genitourinary 1.03 0.952 – 1.11 0.475 729 7284 all phecode
619.2 Disorders of uterus, NEC Genitourinary 1.01 0.973 – 1.05 0.652 3324 33273 all phecode
619.3 Noninflammatory disorders of cervix Genitourinary 1.01 0.971 – 1.05 0.657 2860 28608 all phecode
619.4 Noninflammatory disorders of vagina Genitourinary 1.07 1.02 – 1.12 0.0099 1768 17669 all phecode
619.5 Noninflammatory disorders of vulva and perineum Genitourinary 1.09 1.03 – 1.16 0.00202 1350 13489 all phecode
620 Dysplasia of female genital organs Genitourinary 1.02 0.799 – 1.29 0.9 72 720 all phecode
621 Endometrial hyperplasia Genitourinary 0.984 0.925 – 1.05 0.614 1129 11294 all phecode
622 Polyp of female genital organs Genitourinary 0.982 0.962 – 1 0.0821 10480 104803 all phecode
622.1 Polyp of corpus uteri Genitourinary 0.977 0.955 – 1 0.0564 7857 78601 all phecode
622.2 Mucous polyp of cervix Genitourinary 0.985 0.951 – 1.02 0.397 3442 34387 all phecode
623 Hypertrophy of female genital organs Genitourinary 1.02 0.966 – 1.08 0.431 1268 12684 all phecode
624 Symptoms involving female genital tract Genitourinary 0.935 0.87 – 1.01 0.0712 797 7961 all phecode
624.1 Dystrophy of female genital tract Genitourinary 0.957 0.838 – 1.09 0.51 237 2365 all phecode
624.2 Atrophy of female genital tract Genitourinary 0.921 0.837 – 1.01 0.0943 440 4398 all phecode
624.9 stress incontinence, female Genitourinary 1.1 1.07 – 1.13 3.54e-12 5865 58634 all phecode
625
Pain and other symptoms associated with female
Pain and other symptoms associated with female genital organs
 Genitourinary 1.09 1.04 – 1.13 3.32e-05 2876 28740 all phecode
625.1 Dyspareunia Genitourinary 1.08 1.01 – 1.14 0.0168 1188 11891 all phecode
626
Disorders of menstruation and other abnormal
Disorders of menstruation and other abnormal bleeding from female genital tract
 Genitourinary 1.06 1.05 – 1.08 2.04e-13 16168 115018 all phecode
626.1 Irregular menstrual cycle/bleeding Genitourinary 1.07 1.05 – 1.09 1.89e-13 14110 109918 all phecode
626.11 Absent or infrequent menstruation Genitourinary 1.25 1.03 – 1.52 0.0238 109 1099 all phecode
626.12 Excessive or frequent menstruation Genitourinary 1.08 1.05 – 1.1 3.63e-12 9727 91749 all phecode
626.13 Irregular menstrual cycle Genitourinary 1.06 1.01 – 1.11 0.0191 1985 19829 all phecode
626.14 Irregular menstrual bleeding Genitourinary 1.06 1.02 – 1.1 0.000726 3804 38021 all phecode
626.2 Dysmenorrhea Genitourinary 1.17 1.11 – 1.23 4.92e-10 1778 17767 all phecode
626.4 Premenstrual tension syndromes Genitourinary 1.38 1.17 – 1.62 0.00016 159 1587 all phecode
626.8 Infertility, female Genitourinary 0.988 0.934 – 1.04 0.656 1362 13613 all phecode
627 Menopausal and postmenopausal disorders Genitourinary 1.01 0.994 – 1.04 0.158 10392 103948 all phecode
627.1 Postmenopausal bleeding Genitourinary 1.01 0.989 – 1.03 0.347 9042 90439 all phecode
627.2 Symptomatic menopause Genitourinary 1.22 1.04 – 1.42 0.012 183 1826 all phecode
627.3 Postmenopausal atrophic vaginitis Genitourinary 0.976 0.918 – 1.04 0.451 1111 11115 all phecode
627.4 Premenopausal menorrhagia Genitourinary 0.954 0.847 – 1.07 0.437 310 3097 all phecode
628 Ovarian cyst Genitourinary 1.08 1.05 – 1.11 2.91e-07 4747 47482 all phecode
634 Miscarriage; stillbirth Pregnancy Complications 1.01 0.98 – 1.04 0.568 5218 36422 all phecode
634.1 Missed abortion/Hydatidiform mole Pregnancy Complications 0.959 0.902 – 1.02 0.176 1136 11300 all phecode
634.3 Ectopic pregnancy Pregnancy Complications 1.1 0.981 – 1.23 0.104 331 3305 all phecode
635
Hemorrhage during pregnancy; childbirth and
Hemorrhage during pregnancy; childbirth and postpartum
 Pregnancy Complications 0.952 0.909 – 0.997 0.0369 1974 17372 all phecode
635.2
Antepartum hemorrhage, abruptio placentae, and
Antepartum hemorrhage, abruptio placentae, and placenta previa
 Pregnancy Complications 0.967 0.901 – 1.04 0.34 866 8614 all phecode
635.3 Placenta previa and abruptio placenta Pregnancy Complications 0.92 0.868 – 0.974 0.00421 1270 12306 all phecode
636
Early or threatened labor; hemorrhage in early
Early or threatened labor; hemorrhage in early pregnancy
 Pregnancy Complications 1.01 0.972 – 1.06 0.516 2347 19972 all phecode
636.2 Early onset of delivery Pregnancy Complications 0.976 0.899 – 1.06 0.56 617 6144 all phecode
636.3 Hemorrhage in early pregnancy Pregnancy Complications 1.02 0.96 – 1.09 0.5 1082 10766 all phecode
638 Other high-risk pregnancy Pregnancy Complications 0.989 0.776 – 1.26 0.93 70 700 all phecode
642
Hypertension complicating pregnancy
Hypertension complicating pregnancy, childbirth, and the puerperium
 Pregnancy Complications 0.94 0.885 – 0.999 0.0481 1110 11074 all phecode
642.1 Preeclampsia and eclampsia Pregnancy Complications 0.916 0.816 – 1.03 0.139 307 3058 all phecode
643 Excessive vomiting in pregnancy Pregnancy Complications 0.86 0.748 – 0.989 0.0338 215 2149 all phecode
643.1 Hyperemesis gravidarum Pregnancy Complications 0.792 0.671 – 0.936 0.00624 153 1525 all phecode
645 Late pregnancy and failed induction Pregnancy Complications 1.02 0.959 – 1.08 0.599 1250 12450 all phecode
646 Other complications of pregnancy NEC Pregnancy Complications 1.02 0.976 – 1.06 0.39 2228 20847 all phecode
647
Infectious and parasitic complications
Infectious and parasitic complications affecting pregnancy
 Pregnancy Complications 0.953 0.747 – 1.21 0.695 68 679 all phecode
647.1
Infections of genitourinary tract during
Infections of genitourinary tract during pregnancy
 Pregnancy Complications 1.05 0.926 – 1.18 0.472 275 2748 all phecode
649
Other conditions or status of the mother
Other conditions or status of the mother complicating pregnancy, childbirth, or the puerperium
 Pregnancy Complications 1.16 0.945 – 1.41 0.158 113 1129 all phecode
649.1
Diabetes or abnormal glucose tolerance
Diabetes or abnormal glucose tolerance complicating pregnancy
 Pregnancy Complications 1 0.867 – 1.16 0.982 193 1922 all phecode
650 Normal delivery Pregnancy Complications 0.962 0.918 – 1.01 0.102 1922 18973 all phecode
651 Multiple gestation Pregnancy Complications 1.03 0.924 – 1.15 0.588 346 3454 all phecode
652
Malposition and malpresentation of fetus or
Malposition and malpresentation of fetus or obstruction
 Pregnancy Complications 0.964 0.917 – 1.01 0.14 1716 16521 all phecode
653
Problems associated with amniotic cavity and
Problems associated with amniotic cavity and membranes
 Pregnancy Complications 0.904 0.856 – 0.954 0.00027 1401 13649 all phecode
654
Other and unspecified complications of birth
Other and unspecified complications of birth; puerperium affecting management of mother
 Pregnancy Complications 1.03 0.822 – 1.3 0.781 74 739 all phecode
655
Known or suspected fetal abnormality affecting
Known or suspected fetal abnormality affecting management of mother
 Pregnancy Complications 0.961 0.931 – 0.992 0.0145 4306 29454 all phecode
656 Other perinatal conditions of fetus or newborn Pregnancy Complications 0.927 0.764 – 1.13 0.445 109 1080 all phecode
661 Fetal distress and abnormal forces of labor Pregnancy Complications 0.928 0.889 – 0.969 0.000771 2265 18397 all phecode
663
Umbilical cord complications during labor and
Umbilical cord complications during labor and delivery
 Pregnancy Complications 0.963 0.883 – 1.05 0.397 532 5316 all phecode
665 Obstetrical/birth trauma Pregnancy Complications 0.927 0.9 – 0.955 4.46e-07 5313 29472 all phecode
669 Complications of labor and delivery NEC Pregnancy Complications 0.926 0.889 – 0.964 0.000203 2552 21174 all phecode
671
Venous/cerebrovascular complications embolism
Venous/cerebrovascular complications embolism in pregnancy and the puerperium
 Pregnancy Complications 1.01 0.858 – 1.19 0.917 164 1628 all phecode
674 Other complications of the puerperium NEC Pregnancy Complications 0.991 0.873 – 1.13 0.893 262 2605 all phecode
676
Other disorders of the breast associated with
Other disorders of the breast associated with childbirth and disorders of lactation
 Pregnancy Complications 0.979 0.765 – 1.25 0.866 63 624 all phecode
679 Complications of in utero procedures Dermatologic 0.821 0.626 – 1.08 0.153 53 530 all phecode
681 Superficial cellulitis and abscess Dermatologic 1.11 1.09 – 1.14 1.22e-17 7200 72225 all phecode
681.1 Cellulitis and abscess of fingers/toes Dermatologic 1.02 0.938 – 1.11 0.609 563 5647 all phecode
681.2 Cellulitis and abscess of face/neck Dermatologic 1.14 1.04 – 1.25 0.00396 520 5208 all phecode
681.3 Cellulitis and abscess of arm/hand Dermatologic 1.11 1.08 – 1.15 2.99e-14 5481 55014 all phecode
681.5 Cellulitis and abscess of leg, except foot Dermatologic 1.11 1.08 – 1.15 3.76e-14 5487 55074 all phecode
681.6 Cellulitis and abscess of foot, toe Dermatologic 1.11 1.08 – 1.15 4.06e-14 5444 54643 all phecode
681.7 Cellulitis and abscess of trunk Dermatologic 1.2 1.11 – 1.31 2.1e-05 597 5987 all phecode
686
Other local infections of skin and subcutaneous
Other local infections of skin and subcutaneous tissue
 Dermatologic 1.13 1.06 – 1.19 3.83e-05 1337 13427 all phecode
686.1 Carbuncle and furuncle Dermatologic 1.16 1.11 – 1.21 3.04e-11 2284 22925 all phecode
686.3 Pilonidal cyst Dermatologic 1.32 1.21 – 1.44 2.47e-10 583 5837 all phecode
686.4 Pyogenic granuloma Dermatologic 0.91 0.818 – 1.01 0.0827 362 3615 all phecode
687 Symptoms affecting skin Dermatologic 1.06 0.974 – 1.16 0.172 548 5508 all phecode
687.1 Rash and other nonspecific skin eruption Dermatologic 1.08 1.03 – 1.13 0.000629 2146 21470 all phecode
687.2 Localized superficial swelling, mass, or lump Dermatologic 1.02 0.903 – 1.15 0.761 283 2839 all phecode
687.3 Changes in skin texture Dermatologic 1.16 0.951 – 1.41 0.142 106 1070 all phecode
687.4 Disturbance of skin sensation Dermatologic 1.1 1.06 – 1.14 1.96e-06 2884 28859 all phecode
689 Disorder of skin and subcutaneous tissue NOS Dermatologic 1.04 1.01 – 1.07 0.0028 5747 57521 all phecode
690 Erythematosquamous dermatosis Dermatologic 1 0.795 – 1.26 0.994 71 710 all phecode
690.1 Seborrheic dermatitis Dermatologic 0.962 0.729 – 1.27 0.784 53 530 all phecode
691 Congenital anomalies of skin Dermatologic 1.09 0.901 – 1.32 0.373 120 1199 all phecode
694 Dyschromia and Vitiligo Dermatologic 1.01 0.946 – 1.08 0.763 986 9854 all phecode
694.1 Vitiligo Dermatologic 1.16 0.883 – 1.52 0.289 60 599 all phecode
694.2 Other dyschromia Dermatologic 1.02 0.944 – 1.09 0.666 782 7821 all phecode
694.3 Vascular disorders of skin Dermatologic 0.975 0.806 – 1.18 0.793 117 1170 all phecode
695 Erythematous conditions Dermatologic 1.1 1.05 – 1.15 1.75e-05 2379 23813 all phecode
695.1 Toxic erythema Dermatologic 1.24 1.03 – 1.5 0.0249 109 1090 all phecode
695.2 Bullous dermatoses Dermatologic 1.08 0.907 – 1.29 0.38 137 1365 all phecode
695.21 Dermatitis herpetiformis Dermatologic 0.989 0.76 – 1.29 0.933 57 569 all phecode
695.22 Pemphigus and pemphigoid Dermatologic 1.03 0.804 – 1.31 0.832 73 727 all phecode
695.3 Rosacea Dermatologic 1.09 0.974 – 1.22 0.13 309 3097 all phecode
695.4 Lupus (localized and systemic) Dermatologic 1.12 1.01 – 1.24 0.0314 411 4114 all phecode
695.41 Cutaneous lupus erythematosus Dermatologic 1.28 1.07 – 1.54 0.00778 130 1295 all phecode
695.42 Systemic lupus erythematosus Dermatologic 1.08 0.969 – 1.21 0.157 340 3407 all phecode
695.7 Prurigo and Lichen Dermatologic 1.09 1.01 – 1.18 0.0197 775 7760 all phecode
695.8 Other specified erythematous conditions Dermatologic 1.18 1.04 – 1.36 0.0139 236 2359 all phecode
695.81 Erythema nodosum Dermatologic 1.1 0.868 – 1.39 0.441 76 760 all phecode
695.9 Unspecified erythematous condition Dermatologic 1.04 0.94 – 1.14 0.476 467 4672 all phecode
696 Psoriasis and related disorders Dermatologic 1.19 1.14 – 1.24 3.43e-15 2252 22509 all phecode
696.4 Psoriasis Dermatologic 1.19 1.14 – 1.24 1.04e-14 2198 21969 all phecode
696.41 Psoriasis vulgaris Dermatologic 1.22 1.16 – 1.29 5.61e-15 1680 16796 all phecode
696.42 Psoriatic arthropathy Dermatologic 1.13 1.05 – 1.22 0.00167 706 7052 all phecode
697 Sarcoidosis Dermatologic 0.927 0.848 – 1.01 0.0986 539 5373 all phecode
698 Pruritus and related conditions Dermatologic 1.09 1.02 – 1.18 0.016 782 7814 all phecode
700 Corns and callosities Dermatologic 1.32 1.17 – 1.49 9.87e-06 291 2904 all phecode
701
Other hypertrophic and atrophic conditions of
Other hypertrophic and atrophic conditions of skin
 Dermatologic 1.08 1.05 – 1.12 3.03e-07 4663 46650 all phecode
701.1 Keratoderma, acquired Dermatologic 1.16 0.928 – 1.44 0.195 87 870 all phecode
701.2 Scar conditions and fibrosis of skin Dermatologic 1.08 1.03 – 1.12 0.000753 2348 23478 all phecode
701.3 Circumscribed scleroderma Dermatologic 1.02 0.788 – 1.32 0.89 61 610 all phecode
701.4 Keloid scar Dermatologic 1.2 1.05 – 1.38 0.00953 216 2159 all phecode
701.5 Abnormal granulation tissue Dermatologic 0.971 0.88 – 1.07 0.551 455 4568 all phecode
701.6 Acquired acanthosis nigricans Dermatologic 1.13 0.918 – 1.38 0.254 102 1019 all phecode
702
Degenerative skin conditions and other
Degenerative skin conditions and other dermatoses
 Dermatologic 1 0.976 – 1.03 0.81 5459 54587 all phecode
702.1 Actinic keratosis Dermatologic 1.01 0.966 – 1.05 0.76 2585 25842 all phecode
702.2 Seborrheic keratosis Dermatologic 0.999 0.962 – 1.04 0.94 3078 30772 all phecode
703 Diseases of nail, NOS Dermatologic 1.07 0.958 – 1.19 0.229 354 3539 all phecode
703.1 Ingrowing nail Dermatologic 1.05 0.987 – 1.13 0.115 966 9660 all phecode
704 Diseases of hair and hair follicles Dermatologic 1.07 1.04 – 1.11 5.51e-07 5267 52727 all phecode
704.1 Alopecia Dermatologic 1.06 0.885 – 1.27 0.526 125 1269 all phecode
704.8
Other specified diseases of hair and hair
Other specified diseases of hair and hair follicles
 Dermatologic 0.953 0.753 – 1.21 0.691 76 759 all phecode
705 Disorders of sweat glands Dermatologic 1.59 1.38 – 1.82 8.44e-11 228 2287 all phecode
705.3 Hidradenitis Dermatologic 1.7 1.45 – 1.99 3.53e-11 186 1868 all phecode
705.8 Hyperhidrosis Dermatologic 1.1 1.02 – 1.2 0.0205 591 5919 all phecode
706 Diseases of sebaceous glands Dermatologic 1.11 1.09 – 1.14 1.05e-19 8317 83195 all phecode
706.1 Acne Dermatologic 1.27 1.01 – 1.6 0.0439 78 779 all phecode
706.2 Sebaceous cyst Dermatologic 1.11 1.08 – 1.13 4.71e-19 8787 87882 all phecode
707 Chronic ulcer of skin Dermatologic 1.16 1.1 – 1.21 8.75e-10 1953 19654 all phecode
707.1 Decubitus ulcer Dermatologic 1.2 1.12 – 1.29 1.36e-07 909 9097 all phecode
709 Diffuse diseases of connective tissue Dermatologic 1.1 1.06 – 1.14 2.12e-07 3432 34317 all phecode
709.2 Sicca syndrome Dermatologic 1.03 0.942 – 1.14 0.48 508 5073 all phecode
709.3 Systemic sclerosis Dermatologic 1.02 0.868 – 1.19 0.838 176 1753 all phecode
709.6
Other specified diffuse diseases of connective
Other specified diffuse diseases of connective tissue
 Dermatologic 1.17 0.915 – 1.51 0.207 65 649 all phecode
709.7 Unspecified diffuse connective tissue disease Dermatologic 1.12 1.08 – 1.17 1.52e-08 2714 27144 all phecode
710
Osteomyelitis, periostitis, and other
Osteomyelitis, periostitis, and other infections involving bone
 Musculoskeletal 1.21 1.11 – 1.31 1.31e-05 602 6034 all phecode
710.1 Osteomyelitis Musculoskeletal 1.21 1.1 – 1.32 3.57e-05 556 5574 all phecode
710.12 Chronic osteomyelitis Musculoskeletal 1.19 1.03 – 1.39 0.0183 194 1947 all phecode
710.19 Unspecified osteomyelitis Musculoskeletal 1.22 1.09 – 1.35 0.000282 398 3997 all phecode
711 Arthropathy associated with infections Musculoskeletal 1.13 1.02 – 1.25 0.018 421 4225 all phecode
711.1 Pyogenic arthritis Musculoskeletal 1.2 1.07 – 1.34 0.0024 328 3296 all phecode
712 Infective connective tissue disorders Musculoskeletal 1.19 0.944 – 1.49 0.142 81 810 all phecode
713
Arthropathy associated with other disorders
Arthropathy associated with other disorders classified elsewhere
 Musculoskeletal 1.24 1.05 – 1.47 0.0116 148 1499 all phecode
713.5
Arthropathy associated with neurological
Arthropathy associated with neurological disorders
 Musculoskeletal 1.45 1.12 – 1.86 0.00444 65 669 all phecode
714
Rheumatoid arthritis and other inflammatory
Rheumatoid arthritis and other inflammatory polyarthropathies
 Musculoskeletal 1.19 1.15 – 1.22 1.79e-29 4832 48320 all phecode
714.1 Rheumatoid arthritis Musculoskeletal 1.19 1.16 – 1.23 3.61e-28 4372 43714 all phecode
715 Other inflammatory spondylopathies Musculoskeletal 1.16 1.1 – 1.22 2.25e-08 1659 16588 all phecode
715.1 Sacroiliitis NEC Musculoskeletal 1.07 0.886 – 1.3 0.477 113 1129 all phecode
715.2 Ankylosing spondylitis Musculoskeletal 1.09 1 – 1.18 0.0487 618 6177 all phecode
716 Other arthropathies Musculoskeletal 1.14 1.13 – 1.16 7.43e-126 37478 265375 all phecode
716.1 Unspecified polyarthropathy or polyarthritis Musculoskeletal 1.18 1.14 – 1.22 3.54e-20 3505 35090 all phecode
716.2 Unspecified monoarthritis Musculoskeletal 1.13 1.11 – 1.15 9.78e-45 15522 155339 all phecode
716.9 Arthropathy NOS Musculoskeletal 1.14 1.13 – 1.16 1.34e-122 35944 262308 all phecode
717 Polymyalgia Rheumatica Musculoskeletal 1.13 1.06 – 1.2 7.47e-05 1145 11480 all phecode
720 Spinal stenosis Musculoskeletal 1.2 1.16 – 1.24 3.1e-25 3705 37091 all phecode
721 Spondylosis and allied disorders Musculoskeletal 1.18 1.15 – 1.21 6.37e-44 7832 78318 all phecode
721.1 Spondylosis without myelopathy Musculoskeletal 1.18 1.14 – 1.21 3.48e-28 5045 50451 all phecode
721.2 Spondylosis with myelopathy Musculoskeletal 1.13 0.975 – 1.31 0.104 189 1899 all phecode
721.8 Other allied disorders of spine Musculoskeletal 1.18 1.05 – 1.32 0.00444 352 3519 all phecode
722 Intervertebral disc disorders Musculoskeletal 1.18 1.16 – 1.21 6.99e-51 8978 89848 all phecode
722.1 Displacement of intervertebral disc Musculoskeletal 1.27 1.16 – 1.39 1.94e-07 512 5116 all phecode
722.6 Degeneration of intervertebral disc Musculoskeletal 1.2 1.15 – 1.24 2.02e-19 2831 28328 all phecode
722.8 Postlaminectomy syndrome Musculoskeletal 1.32 1.05 – 1.67 0.0194 67 669 all phecode
722.9 Other and unspecified disc disorder Musculoskeletal 1.16 1.13 – 1.2 4.99e-21 4407 44127 all phecode
723 Other disorders of cervical region Musculoskeletal 1.23 1.12 – 1.34 1.19e-05 517 5173 all phecode
723.1 Torticollis Musculoskeletal 1.12 0.912 – 1.36 0.289 107 1068 all phecode
724 Other and unspecified disorders of back Musculoskeletal 1.16 1.11 – 1.22 2.08e-10 2052 20514 all phecode
724.1 Disorders of sacrum Musculoskeletal 1.18 1.07 – 1.31 0.00163 403 4024 all phecode
724.2 Disorders of coccyx Musculoskeletal 1.17 1.06 – 1.3 0.00275 406 4054 all phecode
724.8 Other symptoms referable to back Musculoskeletal 1.39 1.07 – 1.81 0.0135 63 630 all phecode
724.9 Other unspecified back disorders Musculoskeletal 1.15 1.1 – 1.22 4.67e-08 1614 16139 all phecode
726 Peripheral enthesopathies and allied syndromes Musculoskeletal 1.12 1.1 – 1.14 1.92e-37 14663 146691 all phecode
726.1 Enthesopathy Musculoskeletal 1.11 1.08 – 1.13 4.68e-21 9589 95900 all phecode
726.2 Synoviopathy Musculoskeletal 1.17 1.05 – 1.31 0.00478 334 3336 all phecode
726.3 Bursitis Musculoskeletal 1.11 1.03 – 1.19 0.00459 854 8573 all phecode
727 Other disorders of synovium, tendon, and bursa Musculoskeletal 1.11 1.08 – 1.14 2.67e-17 7331 73332 all phecode
727.1 Synovitis and tenosynovitis Musculoskeletal 1.13 1.08 – 1.17 2.62e-09 2737 27406 all phecode
727.2 Bursitis disorders Musculoskeletal 1.13 0.927 – 1.39 0.222 103 1029 all phecode
727.4 Ganglion and cyst of synovium, tendon, and bursa Musculoskeletal 1.09 1.05 – 1.13 1.33e-05 3109 31085 all phecode
727.5 Rupture of synovium Musculoskeletal 1.12 1.03 – 1.22 0.00964 586 5854 all phecode
727.6 Rupture of tendon, nontraumatic Musculoskeletal 1.11 0.993 – 1.24 0.0658 353 3527 all phecode
727.7 Contracture of tendon (sheath) Musculoskeletal 1.11 0.927 – 1.33 0.256 143 1429 all phecode
728 Disorders of muscle, ligament, and fascia Musculoskeletal 1.06 1.02 – 1.1 0.000972 3677 36788 all phecode
728.2 Laxity of ligament or hypermobility syndrome Musculoskeletal 1.07 0.964 – 1.18 0.211 412 4115 all phecode
728.7 Fasciitis Musculoskeletal 1.06 1.02 – 1.09 0.00165 3803 38045 all phecode
728.71
Contracture of palmar fascia [Dupuytren's
Contracture of palmar fascia [Dupuytren's disease]
 Musculoskeletal 1.06 1.02 – 1.09 0.00223 3477 34788 all phecode
729 Other disorders of soft tissues Musculoskeletal 1.15 1.12 – 1.18 4.98e-25 6014 60309 all phecode
729.1 Rheumatism, unspecified and fibrositis Musculoskeletal 1.14 1.07 – 1.22 5.41e-05 1005 10063 all phecode
729.3 Panniculitis Musculoskeletal 1.08 0.881 – 1.32 0.464 101 1009 all phecode
731
Osteitis deformans and osteopathies associated
Osteitis deformans and osteopathies associated with other disorders classified elsewhere
 Musculoskeletal 1.06 0.94 – 1.21 0.324 276 2758 all phecode
731.1 Osteitis deformans [Paget's disease of bone] Musculoskeletal 1.09 0.956 – 1.24 0.202 261 2609 all phecode
732 Osteochondropathies Musculoskeletal 1.06 0.959 – 1.17 0.263 467 4679 all phecode
732.1 Juvenile osteochondrosis Musculoskeletal 1.1 0.954 – 1.28 0.183 207 2068 all phecode
732.7 Osteochondritis dissecans Musculoskeletal 1 0.769 – 1.31 0.975 57 570 all phecode
733 Other disorders of bone and cartilage Musculoskeletal 1.11 1.06 – 1.16 3.64e-05 1777 17814 all phecode
733.2 Cyst of bone Musculoskeletal 1.07 0.954 – 1.21 0.239 311 3115 all phecode
733.4 Aseptic necrosis of bone Musculoskeletal 1.09 1 – 1.2 0.0468 540 5393 all phecode
733.6 Costochondritis Musculoskeletal 1.1 0.911 – 1.32 0.332 128 1276 all phecode
733.8 Malunion and nonunion of fracture Musculoskeletal 1.11 1.04 – 1.18 0.000613 1231 12313 all phecode
733.9 Chondromalacia Musculoskeletal 1.22 1.01 – 1.47 0.036 121 1206 all phecode
735 Acquired foot deformities Musculoskeletal 1.07 1.04 – 1.09 1.91e-09 9603 96090 all phecode
735.1 Flat foot Musculoskeletal 1.03 0.887 – 1.2 0.676 189 1910 all phecode
735.2 Acquired toe deformities Musculoskeletal 1.08 1.05 – 1.11 6.32e-07 5070 50712 all phecode
735.21 Hammer toe (acquired) Musculoskeletal 1.1 1.05 – 1.15 0.000133 1929 19324 all phecode
735.23 Hallux rigidus Musculoskeletal 1.04 0.987 – 1.1 0.138 1555 15527 all phecode
735.3 Hallux valgus (Bunion) Musculoskeletal 1.06 1.04 – 1.09 2.13e-06 6643 66463 all phecode
736 Other acquired deformities of limbs Musculoskeletal 1.09 1.04 – 1.15 0.000767 1627 16282 all phecode
736.2 Acquired deformities of finger Musculoskeletal 1.01 0.888 – 1.15 0.861 248 2476 all phecode
737 Curvature of spine Musculoskeletal 1.09 1.03 – 1.16 0.00449 1128 11300 all phecode
737.3 Kyphoscoliosis and scoliosis Musculoskeletal 1.09 1.02 – 1.16 0.00768 1061 10632 all phecode
738 Other acquired musculoskeletal deformity Musculoskeletal 1.19 1.13 – 1.25 1.46e-12 1904 19058 all phecode
738.4 Acquired spondylolisthesis Musculoskeletal 1.19 1.12 – 1.25 4.15e-10 1513 15147 all phecode
739 Contracture of joint Musculoskeletal 1.08 0.981 – 1.19 0.118 488 4884 all phecode
740 Osteoarthrosis Musculoskeletal 1.12 1.1 – 1.13 6.54e-67 27707 231603 all phecode
740.1 Osteoarthritis; localized Musculoskeletal 1.1 1.09 – 1.12 6.27e-34 17412 169419 all phecode
740.11 Osteoarthrosis, localized, primary Musculoskeletal 1.1 1.07 – 1.12 3.77e-17 8974 89750 all phecode
740.12 Osteoarthrosis, localized, secondary Musculoskeletal 1.13 1.01 – 1.26 0.0307 348 3474 all phecode
740.2 Osteoarthrosis, generalized Musculoskeletal 1.12 1.03 – 1.22 0.00667 598 5969 all phecode
740.9 Osteoarthrosis NOS Musculoskeletal 1.16 1.14 – 1.18 1.46e-52 12270 122792 all phecode
741 Symptoms and disorders of the joints Musculoskeletal 1.07 1.03 – 1.11 0.000112 3563 35648 all phecode
741.1 Ankylosis of joint Musculoskeletal 0.848 0.685 – 1.05 0.132 102 1019 all phecode
741.2 Stiffness of joint Musculoskeletal 1.07 0.983 – 1.16 0.118 614 6146 all phecode
741.3 Difficulty in walking Musculoskeletal 1.2 1.02 – 1.42 0.0296 154 1540 all phecode
741.4 Joint effusions Musculoskeletal 1.08 1.02 – 1.14 0.0089 1418 14197 all phecode
741.5 Hemarthrosis Musculoskeletal 1.05 0.87 – 1.27 0.597 110 1100 all phecode
741.6 Villonodular synovitis Musculoskeletal 1.07 0.826 – 1.4 0.594 54 535 all phecode
742 Derangement of joint, non-traumatic Musculoskeletal 1.09 1.05 – 1.14 4.93e-06 2843 28441 all phecode
742.1 Loose body in joint Musculoskeletal 1.12 1 – 1.25 0.0446 333 3337 all phecode
742.2
Pathological, developmental or recurrent
Pathological, developmental or recurrent dislocation
 Musculoskeletal 1.1 0.891 – 1.35 0.386 95 960 all phecode
742.8 Articular cartilage disorder Musculoskeletal 1.12 1.03 – 1.23 0.0126 500 4996 all phecode
742.9 Other derangement of joint Musculoskeletal 1.07 1.03 – 1.13 0.00214 1993 19926 all phecode
743
Osteoporosis, osteopenia and pathological
Osteoporosis, osteopenia and pathological fracture
 Musculoskeletal 1.05 1.02 – 1.07 0.000117 7563 75729 all phecode
743.1 Osteoporosis Musculoskeletal 1.04 1.02 – 1.07 0.00177 6400 64107 all phecode
743.11 Osteoporosis NOS Musculoskeletal 1.04 1.01 – 1.07 0.00827 5549 55604 all phecode
743.13 Other specified osteoporosis Musculoskeletal 1.14 1.04 – 1.25 0.00343 529 5283 all phecode
743.2 Pathologic fracture Musculoskeletal 1.2 1.09 – 1.31 0.000124 516 5179 all phecode
743.9
Osteopenia or other disorder of bone and
Osteopenia or other disorder of bone and cartilage
 Musculoskeletal 1.06 0.984 – 1.13 0.129 815 8144 all phecode
745 Pain in joint Musculoskeletal 1.15 1.12 – 1.18 2.35e-32 7975 79789 all phecode
747 Cardiac and circulatory congenital anomalies Congenital Anomalies 1.12 1.07 – 1.16 2.55e-08 2802 28058 all phecode
747.1 Cardiac congenital anomalies Congenital Anomalies 1.11 1.07 – 1.16 3.79e-07 2628 26323 all phecode
747.11 Cardiac shunt/ heart septal defect Congenital Anomalies 1.12 1.03 – 1.22 0.00801 584 5838 all phecode
747.12 Valvular heart disease/ heart chambers Congenital Anomalies 0.978 0.854 – 1.12 0.747 235 2358 all phecode
747.13 Congenital anomalies of great vessels Congenital Anomalies 1.12 1.06 – 1.17 9.17e-06 1816 18200 all phecode
747.2
Congenital anomalies of peripheral vascular
Congenital anomalies of peripheral vascular system
 Congenital Anomalies 1.16 0.997 – 1.36 0.0553 167 1680 all phecode
748 Anomalies of respiratory system, congenital Congenital Anomalies 1.07 0.8 – 1.42 0.666 51 510 all phecode
749 Congenital anomalies of face and neck Congenital Anomalies 1.06 0.946 – 1.2 0.3 303 3029 all phecode
750 Digestive congenital anomalies Congenital Anomalies 0.951 0.879 – 1.03 0.208 686 6870 all phecode
750.1 Upper gastrointestinal congenital anomalies Congenital Anomalies 0.936 0.836 – 1.05 0.25 327 3263 all phecode
750.13 Congenital anomalies of mouth/tongue Congenital Anomalies 0.925 0.799 – 1.07 0.295 191 1909 all phecode
750.2 Lower gastrointestinal congenital anomalies Congenital Anomalies 0.956 0.858 – 1.07 0.42 356 3574 all phecode
750.21 Congenital anomalies of intestine Congenital Anomalies 0.93 0.813 – 1.06 0.294 225 2256 all phecode
750.22
Congenital anomaly of gallbladder, bile ducts
Congenital anomaly of gallbladder, bile ducts, liver, pancreas
 Congenital Anomalies 0.979 0.809 – 1.19 0.829 117 1179 all phecode
751 Genitourinary congenital anomalies Congenital Anomalies 1.07 1.01 – 1.13 0.0143 1527 15286 all phecode
751.1 Congenital anomalies of genital organs Congenital Anomalies 1.06 0.976 – 1.14 0.176 694 6932 all phecode
751.11 Congenital anomalies of female genital organs Congenital Anomalies 1.05 0.953 – 1.16 0.329 455 4546 all phecode
751.12 Congenital anomalies of male genital organs Congenital Anomalies 1.03 0.901 – 1.19 0.632 222 2217 all phecode
751.2 Congenital anomalies of urinary system Congenital Anomalies 1.07 0.994 – 1.15 0.075 836 8385 all phecode
751.21 Cystic kidney disease Congenital Anomalies 1.03 0.93 – 1.14 0.581 424 4246 all phecode
751.22 Other specified congenital anomalies of kidney Congenital Anomalies 1.13 1.01 – 1.26 0.0335 333 3346 all phecode
752 Nervous system congenital anomalies Congenital Anomalies 1.06 0.942 – 1.19 0.344 328 3307 all phecode
752.1 Neural tube defects Congenital Anomalies 1.07 0.939 – 1.22 0.304 253 2557 all phecode
752.11 Spina bifida Congenital Anomalies 1.14 0.99 – 1.32 0.069 208 2108 all phecode
752.2
Other specified congenital anomalies of nervous
Other specified congenital anomalies of nervous system
 Congenital Anomalies 0.956 0.76 – 1.2 0.703 78 780 all phecode
753 Congenital anomalies of the eye Congenital Anomalies 1.14 0.952 – 1.37 0.152 127 1270 all phecode
753.1 Congenital cataract and lens anomalies Congenital Anomalies 1.13 0.893 – 1.43 0.307 76 760 all phecode
754 Congenital musculoskeletal deformities of spine Congenital Anomalies 1.05 0.863 – 1.28 0.619 109 1099 all phecode
755 Congenital anomalies of limbs Congenital Anomalies 1.08 0.976 – 1.19 0.136 425 4276 all phecode
755.1 Congenital deformities of feet Congenital Anomalies 1.08 0.94 – 1.25 0.269 208 2086 all phecode
755.6
Other congenital anomalies of lower limb
Other congenital anomalies of lower limb, including pelvic girdle
 Congenital Anomalies 1.11 0.941 – 1.31 0.212 160 1620 all phecode
755.61 Congenital hip dysplasia and deformity Congenital Anomalies 1.11 0.906 – 1.36 0.31 106 1070 all phecode
756 Other congenital musculoskeletal anomalies Congenital Anomalies 1.1 1.01 – 1.2 0.0248 587 5872 all phecode
756.3
Congenital anomalies of muscle, tendon, fascia
Congenital anomalies of muscle, tendon, fascia, and connective tissue
 Congenital Anomalies 1.21 0.962 – 1.53 0.103 81 810 all phecode
756.5 Congenital osteodystrophies Congenital Anomalies 1.14 1.03 – 1.26 0.00989 435 4356 all phecode
758 Chromosomal anomalies and genetic disorders Congenital Anomalies 1.08 0.906 – 1.28 0.403 148 1708 all phecode
758.1 Chromosomal anomalies Congenital Anomalies 1.32 1.01 – 1.73 0.0407 60 830 all phecode
759 Other and unspecified congenital anomalies Congenital Anomalies 1.11 0.965 – 1.27 0.145 216 2159 all phecode
759.1 Anomalies of endocrine glands, congenital Congenital Anomalies 1.16 0.944 – 1.43 0.157 96 959 all phecode
760 Back pain Symptoms 1.16 1.14 – 1.18 6.18e-49 11126 111353 all phecode
761 Cervicalgia Symptoms 1.16 1.1 – 1.21 5.29e-09 1791 17901 all phecode
764 Sciatica Symptoms 1.17 1.12 – 1.22 7.88e-13 2372 23732 all phecode
766 Neuralgia, neuritis, and radiculitis NOS Symptoms 1.17 1.1 – 1.25 2.47e-07 1172 11738 all phecode
770 Myalgia and myositis unspecified Symptoms 1.03 0.953 – 1.12 0.43 631 6311 all phecode
771 Musculoskeletal symptoms referable to limbs Symptoms 1.16 1.08 – 1.25 2.89e-05 870 8687 all phecode
771.1 Swelling of limb Symptoms 1.14 1.11 – 1.18 3.07e-17 4617 46330 all phecode
772 Symptoms of the muscles Symptoms 1.08 0.991 – 1.17 0.0801 659 6581 all phecode
773 Pain in limb Symptoms 1.14 1.11 – 1.17 1.39e-23 6209 62203 all phecode
780 Hypothermia/Chills Symptoms 1.16 0.986 – 1.36 0.0742 171 1719 all phecode
781
Symptoms involving nervous and musculoskeletal
Symptoms involving nervous and musculoskeletal systems
 Symptoms 1.15 1.09 – 1.2 1.39e-08 1870 18715 all phecode
782.3 Edema Symptoms 1.18 1.12 – 1.24 2.36e-10 1642 16450 all phecode
782.6 Pallor and flushing Symptoms 1.21 1.03 – 1.41 0.0189 175 1748 all phecode
783 Fever of unknown origin Symptoms 1.05 1.01 – 1.08 0.00627 3911 39105 all phecode
785 Abdominal pain Symptoms 1.1 1.09 – 1.11 3.41e-69 40080 301686 all phecode
788 Syncope and collapse Symptoms 1.04 1.01 – 1.06 0.00109 9069 90813 all phecode
789 Nausea and vomiting Symptoms 1.1 1.08 – 1.12 4.95e-21 11577 115807 all phecode
790 Nonspecific findings on examination of blood Symptoms 1.11 0.941 – 1.31 0.216 150 1500 all phecode
790.1 Elevated sedimentation rate Symptoms 1.11 0.887 – 1.39 0.356 84 840 all phecode
790.6 Other abnormal blood chemistry Symptoms 1.03 1 – 1.06 0.0306 6357 63635 all phecode
791 Gangrene Symptoms 1.16 1.06 – 1.27 0.00101 549 5501 all phecode
792
Abnormal Papanicolaou smear of cervix and
Abnormal Papanicolaou smear of cervix and cervical HPV
 Symptoms 1.24 1 – 1.54 0.0456 98 966 all phecode
793
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of musculoskeletal system
 Symptoms 1.07 0.899 – 1.27 0.454 134 1340 all phecode
793.2
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of other intrathoracic organs (echocardiogram, etc)
 Symptoms 1.07 0.982 – 1.17 0.123 565 5647 all phecode
794
Abnormal results of other function studies
Abnormal results of other function studies (bladder, pancreas, placenta, spleen, etc)
 Symptoms 0.859 0.715 – 1.03 0.102 120 1198 all phecode
797 Shock Symptoms 1.14 0.968 – 1.34 0.117 156 1559 all phecode
797.1 Cardiogenic shock Symptoms 1.1 0.903 – 1.35 0.338 102 1020 all phecode
798 Malaise and fatigue Symptoms 1.07 1.03 – 1.11 0.000334 3408 34103 all phecode
798.1 Chronic fatigue syndrome Symptoms 0.968 0.889 – 1.06 0.464 591 5913 all phecode
800 Fracture of lower limb Injuries & Poisonings 1.08 1.05 – 1.1 2.98e-09 7035 70329 all phecode
800.1 Fracture of neck of femur Injuries & Poisonings 1.07 1.02 – 1.12 0.00795 1815 18152 all phecode
800.2 Fracture of unspecified part of femur Injuries & Poisonings 1.1 0.936 – 1.28 0.253 170 1693 all phecode
800.3 Fracture of tibia and fibula Injuries & Poisonings 1.1 1.05 – 1.15 2.59e-05 2158 21577 all phecode
800.4 Fracture of patella Injuries & Poisonings 1.07 0.997 – 1.16 0.0614 766 7661 all phecode
801 Fracture of ankle and foot Injuries & Poisonings 1.13 1.08 – 1.18 6.21e-08 2205 22041 all phecode
801.1 Fracture of foot Injuries & Poisonings 1.11 1.06 – 1.16 2.5e-05 1835 18346 all phecode
802 Fracture of pelvis Injuries & Poisonings 1.06 0.979 – 1.14 0.153 718 7185 all phecode
803 Fracture of upper limb Injuries & Poisonings 1.02 0.996 – 1.04 0.113 8288 82880 all phecode
803.1 Fracture of humerus Injuries & Poisonings 1.01 0.963 – 1.06 0.616 1691 16883 all phecode
803.2 Fracture of radius and ulna Injuries & Poisonings 0.997 0.969 – 1.03 0.848 5215 52171 all phecode
803.3 Fracture of clavicle or scapula Injuries & Poisonings 1.09 1.04 – 1.15 0.000877 1518 15186 all phecode
804 Fracture of hand or wrist Injuries & Poisonings 1.09 1.05 – 1.13 4.66e-06 3339 33384 all phecode
805
Fracture of vertebral column without mention of
Fracture of vertebral column without mention of spinal cord injury
 Injuries & Poisonings 1.08 1.02 – 1.14 0.00858 1358 13565 all phecode
807 Fracture of ribs Injuries & Poisonings 1.16 1.08 – 1.25 9.57e-05 776 7752 all phecode
809 Fracture of unspecified bones Injuries & Poisonings 1.05 0.992 – 1.11 0.092 1300 12998 all phecode
817 Concussion Injuries & Poisonings 1.04 0.909 – 1.19 0.582 243 2428 all phecode
818 Intracranial hemorrhage (injury) Injuries & Poisonings 1.01 0.929 – 1.11 0.747 522 5213 all phecode
819
Skull and face fracture and other intercranial
Skull and face fracture and other intercranial injury
 Injuries & Poisonings 1.08 1.04 – 1.12 4.61e-05 2957 29596 all phecode
823 Torus fracture Injuries & Poisonings 1.1 1.05 – 1.16 2e-04 1673 16710 all phecode
830 Dislocation Injuries & Poisonings 1.12 1.07 – 1.17 1.25e-06 2088 20872 all phecode
835 Internal derangement of knee Injuries & Poisonings 1.07 1.06 – 1.09 5.11e-17 15221 152247 all phecode
836 Traumatic arthropathy Injuries & Poisonings 1.27 1.16 – 1.4 1.49e-07 526 5267 all phecode
840 Sprains and strains Injuries & Poisonings 0.992 0.903 – 1.09 0.875 470 4697 all phecode
850 Hemorrhage or hematoma complicating a procedure Injuries & Poisonings 1.07 1.04 – 1.1 9.82e-07 5259 52626 all phecode
851
Complications of transplants and reattached
Complications of transplants and reattached limbs
 Injuries & Poisonings 1.12 0.951 – 1.32 0.174 157 1567 all phecode
853 Complication of colostomy or enterostomy Injuries & Poisonings 1.17 1.06 – 1.28 0.000993 501 5010 all phecode
854
Complications of cardiac/vascular device
Complications of cardiac/vascular device, implant, and graft
 Injuries & Poisonings 1.23 1.17 – 1.29 4.86e-17 1826 18238 all phecode
857
Mechanical complication of unspecified
Mechanical complication of unspecified genitourinary device, implant, and graft
 Injuries & Poisonings 1.11 1.05 – 1.18 0.000453 1241 12418 all phecode
858 Complication of internal orthopedic device Injuries & Poisonings 1.16 1.11 – 1.2 1.4e-14 3158 31607 all phecode
859
Complication due to other implant and internal
Complication due to other implant and internal device
 Injuries & Poisonings 1.17 1.13 – 1.22 1.14e-17 3259 32599 all phecode
860 Bone marrow or stem cell transplant Neoplasms 0.798 0.619 – 1.03 0.0805 68 680 all phecode
870 Open wounds of head; neck; and trunk Injuries & Poisonings 1.12 1.09 – 1.16 4.89e-11 3502 35062 all phecode
870.1 Open wound or laceration of eye or eyelid Injuries & Poisonings 1.13 0.993 – 1.28 0.0653 272 2713 all phecode
870.2 Open wound of ear Injuries & Poisonings 1.05 0.908 – 1.21 0.511 196 1949 all phecode
870.3 Other open wound of head and face Injuries & Poisonings 1.12 1.08 – 1.16 8.73e-09 2904 29085 all phecode
870.4 Open wound of nose and sinus Injuries & Poisonings 1.2 1.04 – 1.38 0.0122 220 2199 all phecode
870.6 Open wound of neck Injuries & Poisonings 1.33 1.04 – 1.71 0.0232 68 678 all phecode
871 Open wounds of extremities Injuries & Poisonings 1.18 1.14 – 1.22 6.9e-24 4063 40648 all phecode
871.1 Open wound of hand except finger(s) Injuries & Poisonings 1.27 0.952 – 1.7 0.104 53 530 all phecode
871.2 Open wound of finger(s) Injuries & Poisonings 1.04 0.844 – 1.28 0.714 91 900 all phecode
871.3 Open wound of foot except toe(s) alone Injuries & Poisonings 1.34 1.15 – 1.56 0.000156 178 1785 all phecode
872 Traumatic amputation Injuries & Poisonings 1.12 1.02 – 1.24 0.0192 475 4742 all phecode
873 Broken tooth Injuries & Poisonings 0.958 0.836 – 1.1 0.541 229 2289 all phecode
874 Complication of amputation stump Injuries & Poisonings 1.24 1.06 – 1.45 0.00603 169 1710 all phecode
905
Late effects of musculoskeletal and connective
Late effects of musculoskeletal and connective tissue injuries
 Injuries & Poisonings 1.19 1.01 – 1.39 0.0391 157 1567 all phecode
907 Injuries to the nervous system Injuries & Poisonings 1.18 1.11 – 1.25 1.94e-08 1314 13140 all phecode
915 Superficial injury without mention of infection Injuries & Poisonings 1.1 1.06 – 1.13 1.41e-08 4260 42663 all phecode
916 Contusion Injuries & Poisonings 1.1 1.04 – 1.16 0.000737 1450 14506 all phecode
930 Allergic reaction to food Injuries & Poisonings 1.12 0.962 – 1.3 0.147 179 1807 all phecode
938 Dermatitis due to solar radiation Injuries & Poisonings 0.953 0.859 – 1.06 0.362 389 3899 all phecode
938.2 Chronic dermatitis due to solar radiation Injuries & Poisonings 0.917 0.807 – 1.04 0.184 252 2530 all phecode
939
Atopic/contact dermatitis due to other or
Atopic/contact dermatitis due to other or unspecified
 Dermatologic 1.05 1 – 1.1 0.0297 2094 20961 all phecode
941 Adverse reaction to serum or vaccine Injuries & Poisonings 1.14 0.994 – 1.31 0.0607 225 2249 all phecode
942 Infusion and transfusion reaction Injuries & Poisonings 0.924 0.754 – 1.13 0.444 104 1038 all phecode
946 Anaphylactic shock NOS Injuries & Poisonings 1.21 1.1 – 1.32 3.14e-05 550 5509 all phecode
947 Urticaria Injuries & Poisonings 1.09 0.981 – 1.22 0.109 371 3707 all phecode
949 Allergies, other Injuries & Poisonings 1.09 0.98 – 1.21 0.112 397 3989 all phecode
952
Spinal cord injury without evidence of spinal
Spinal cord injury without evidence of spinal bone injury
 Injuries & Poisonings 1.11 1.01 – 1.23 0.0338 423 4224 all phecode
957 Injury to other and unspecified nerves Injuries & Poisonings 1.27 1.12 – 1.44 0.000189 269 2698 all phecode
958
Certain early complications of trauma or
Certain early complications of trauma or procedure
 Injuries & Poisonings 1.19 1.08 – 1.3 0.000288 491 4926 all phecode
958.1 Postoperative shock Injuries & Poisonings 1.11 0.838 – 1.46 0.478 55 555 all phecode
958.2 Traumatic and surgical subcutaneous emphysema Injuries & Poisonings 1.05 0.84 – 1.32 0.649 74 740 all phecode
960 Poisoning by antibiotics Injuries & Poisonings 1.09 1.07 – 1.1 2.14e-25 18100 181147 all phecode
960.2 Allergy/adverse effect of penicillin Injuries & Poisonings 1.09 1.07 – 1.11 4.02e-25 15846 158623 all phecode
961 Poisoning by other anti-infectives Injuries & Poisonings 1.09 0.987 – 1.2 0.0901 420 4195 all phecode
961.1 Poisoning/allergy of sulfonamides Injuries & Poisonings 1.03 0.958 – 1.1 0.449 869 8703 all phecode
962 Poisoning by hormones and synthetic substitutes Injuries & Poisonings 1.16 1.04 – 1.29 0.00804 371 3707 all phecode
962.3
Hormones and synthetic substitutes causing
Hormones and synthetic substitutes causing adverse effects in therapeutic use
 Injuries & Poisonings 1.2 1.07 – 1.33 0.00129 364 3638 all phecode
963 Poisoning by primarily systemic agents Injuries & Poisonings 1.34 1.17 – 1.54 3.38e-05 223 2228 all phecode
964
Poisoning by agents primarily affecting blood
Poisoning by agents primarily affecting blood constituents
 Injuries & Poisonings 1.13 1.01 – 1.28 0.0389 282 2830 all phecode
964.1 Anticoagulants causing adverse effects Injuries & Poisonings 1.15 1.02 – 1.3 0.02 276 2770 all phecode
965
Poisoning by analgesics, antipyretics, and
Poisoning by analgesics, antipyretics, and antirheumatics
 Injuries & Poisonings 1.17 1.14 – 1.21 3.96e-32 6082 60875 all phecode
965.1
Opiates and related narcotics causing adverse
Opiates and related narcotics causing adverse effects in therapeutic use
 Injuries & Poisonings 1.12 1.06 – 1.2 0.000179 1144 11447 all phecode
965.2
Antirheumatics causing adverse effects in
Antirheumatics causing adverse effects in therapeutic use
 Injuries & Poisonings 1.42 1.29 – 1.56 7.23e-13 476 4767 all phecode
965.3
Salicylates causing adverse effects in
Salicylates causing adverse effects in therapeutic use
 Injuries & Poisonings 1.46 1.32 – 1.62 4.62e-13 403 4045 all phecode
966
Poisoning by anticonvulsants and
Poisoning by anticonvulsants and anti-Parkinsonism drugs
 Injuries & Poisonings 1.23 1.12 – 1.34 1.3e-05 512 5123 all phecode
967
Adverse effects of sedatives or other central
Adverse effects of sedatives or other central nervous system depressants and anesthetics
 Injuries & Poisonings 1.12 1.03 – 1.22 0.00997 583 5843 all phecode
969 Poisoning by psychotropic agents Injuries & Poisonings 1.32 1.26 – 1.38 3.12e-31 1950 19519 all phecode
971
Poisoning by drugs primarily affecting the
Poisoning by drugs primarily affecting the autonomic nervous system
 Injuries & Poisonings 1.39 1.2 – 1.61 9.11e-06 190 1908 all phecode
972
Poisoning by agents primarily affecting the
Poisoning by agents primarily affecting the cardiovascular system
 Injuries & Poisonings 1.34 1.18 – 1.52 6.08e-06 271 2717 all phecode
972.6 Antihypertensive agents causing adverse effects Injuries & Poisonings 1.37 1.1 – 1.72 0.00598 84 849 all phecode
973
Poisoning by agents primarily affecting the
Poisoning by agents primarily affecting the gastrointestinal system
 Injuries & Poisonings 1.45 1.19 – 1.78 0.000246 108 1080 all phecode
974
Poisoning by water, mineral, and uric acid
Poisoning by water, mineral, and uric acid metabolism drugs
 Injuries & Poisonings 1.24 1.01 – 1.52 0.0357 101 1018 all phecode
975
Poisoning by agents primarily acting on the
Poisoning by agents primarily acting on the smooth and skeletal muscles and respiratory system
 Injuries & Poisonings 1.35 1.05 – 1.74 0.0184 64 640 all phecode
976
Poisoning by agents primarily affecting skin &
Poisoning by agents primarily affecting skin & mucous membrane, ophthalmological, otorhinolaryngological, & dental drugs
 Injuries & Poisonings 1.27 0.967 – 1.67 0.0859 58 580 all phecode
977 Personal history of allergy to medicinal agents Injuries & Poisonings 1.27 1.11 – 1.45 0.000372 234 2337 all phecode
979 Adverse drug events and drug allergies Injuries & Poisonings 1.32 1.22 – 1.42 6.16e-12 698 6966 all phecode
981
Toxic effect of (non-ethyl) alcohol and
Toxic effect of (non-ethyl) alcohol and petroleum and other solvents
 Injuries & Poisonings 1.32 1.15 – 1.52 9.91e-05 200 1999 all phecode
986 Toxic effect of carbon monoxide Injuries & Poisonings 1.39 1.07 – 1.8 0.0129 62 620 all phecode
987 Toxic effect of other gases, fumes, or vapors Injuries & Poisonings 1.34 1.09 – 1.66 0.00609 105 1049 all phecode
988 Toxic effect of noxious substances eaten as food Injuries & Poisonings 0.962 0.797 – 1.16 0.684 111 1128 all phecode
989
Toxic effect of other substances, chiefly
Toxic effect of other substances, chiefly nonmedicinal as to source
 Injuries & Poisonings 1.19 0.96 – 1.47 0.113 89 890 all phecode
990 Effects radiation NOS Injuries & Poisonings 1.09 1.05 – 1.13 5.68e-06 3113 31140 all phecode
994 Sepsis and SIRS Injuries & Poisonings 1.08 1.04 – 1.12 5.59e-05 3028 30268 all phecode
994.2 Sepsis Injuries & Poisonings 1.08 1.04 – 1.12 5.59e-05 3028 30268 all phecode
008 Intestinal infection Infectious Diseases 1.08 1.04 – 1.12 3.67e-05 3177 34779 exclusion phecode
008.5 Bacterial enteritis Infectious Diseases 1.11 1.04 – 1.19 0.0019 962 10653 exclusion phecode
008.52 Intestinal infection due to C. difficile Infectious Diseases 1.08 0.939 – 1.24 0.288 230 2513 exclusion phecode
008.6 Viral Enteritis Infectious Diseases 1.06 0.938 – 1.19 0.359 316 3341 exclusion phecode
008.7 Intestinal infection due to protozoa Infectious Diseases 0.544 0.331 – 0.894 0.0163 23 208 exclusion phecode
010 Tuberculosis Infectious Diseases 1.14 0.835 – 1.56 0.407 44 635 exclusion phecode
038 Septicemia Infectious Diseases 1.05 0.996 – 1.11 0.0697 1419 15777 exclusion phecode
038.1 Gram negative septicemia Infectious Diseases 1.13 1 – 1.28 0.0444 307 3119 exclusion phecode
038.2 Gram positive septicemia Infectious Diseases 1.03 0.873 – 1.21 0.749 158 1883 exclusion phecode
041 Bacterial infection NOS Infectious Diseases 1.11 1.07 – 1.15 6.42e-10 4072 46494 exclusion phecode
041.1 Staphylococcus infections Infectious Diseases 1.14 1.07 – 1.21 9.43e-05 1028 11962 exclusion phecode
041.2 Streptococcus infection Infectious Diseases 1.18 1.08 – 1.29 0.000231 558 6335 exclusion phecode
041.4 E. coli Infectious Diseases 1.08 1.01 – 1.16 0.0206 961 10739 exclusion phecode
053 Herpes zoster Infectious Diseases 1.08 0.908 – 1.28 0.385 139 1617 exclusion phecode
053.1 Herpes zoster with nervous system complications Infectious Diseases 1.25 0.879 – 1.78 0.213 29 359 exclusion phecode
054 Herpes simplex Infectious Diseases 1.15 0.898 – 1.47 0.269 78 801 exclusion phecode
070 Viral hepatitis Infectious Diseases 1.15 0.971 – 1.36 0.105 144 2278 exclusion phecode
070.1 Viral hepatitis A Infectious Diseases 1.24 0.814 – 1.9 0.312 22 282 exclusion phecode
070.2 Viral hepatitis B Infectious Diseases 1.42 1.01 – 1.99 0.0445 39 485 exclusion phecode
070.3 Viral hepatitis C Infectious Diseases 1.21 0.883 – 1.66 0.236 36 1048 exclusion phecode
070.4 Chronic hepatitis Infectious Diseases 1.09 0.897 – 1.33 0.378 113 1132 exclusion phecode
070.9 Hepatitis NOS Infectious Diseases 1.07 0.909 – 1.26 0.413 147 1607 exclusion phecode
071 Human immunodeficiency virus [HIV] disease Infectious Diseases 1.23 0.888 – 1.7 0.214 39 543 exclusion phecode
071.1 HIV infection, symptomatic Infectious Diseases 1.19 0.832 – 1.7 0.34 33 438 exclusion phecode
078 Viral warts & HPV Infectious Diseases 0.999 0.896 – 1.11 0.982 358 4009 exclusion phecode
079 Viral infection Infectious Diseases 1.07 1 – 1.14 0.0351 1100 11167 exclusion phecode
079.1 Varicella infection Infectious Diseases 1.1 0.731 – 1.65 0.65 24 281 exclusion phecode
080 Postoperative infection Infectious Diseases 1.06 1.01 – 1.12 0.0295 1460 17445 exclusion phecode
081
Infection/inflammation of internal prosthetic
Infection/inflammation of internal prosthetic device; implant; and graft
 Infectious Diseases 1.05 0.976 – 1.13 0.19 813 9364 exclusion phecode
090
Sexually transmitted infections (not HIV or
Sexually transmitted infections (not HIV or hepatitis)
 Infectious Diseases 1.03 0.705 – 1.51 0.876 29 264 exclusion phecode
1000 Burns Injuries & Poisonings 1.03 0.895 – 1.19 0.671 215 2207 exclusion phecode
1001 Foreign body injury Injuries & Poisonings 1.1 0.997 – 1.22 0.0561 418 4598 exclusion phecode
1002
Symptoms concerning nutrition, metabolism, and
Symptoms concerning nutrition, metabolism, and development
 Injuries & Poisonings 1.03 0.982 – 1.08 0.216 1908 21313 exclusion phecode
1004
Other signs and symptoms involving emotional
Other signs and symptoms involving emotional state
 Injuries & Poisonings 1.12 0.896 – 1.39 0.326 86 1181 exclusion phecode
1005 Other symptoms Injuries & Poisonings 1.06 0.963 – 1.17 0.231 467 5561 exclusion phecode
1006 Crushing injury Injuries & Poisonings 1.02 0.795 – 1.31 0.881 70 957 exclusion phecode
1007 Injury to blood vessels Injuries & Poisonings 1.28 1.01 – 1.62 0.0385 80 964 exclusion phecode
1008 Crushing or internal injury to organs Injuries & Poisonings 1.14 1.01 – 1.28 0.0305 315 3778 exclusion phecode
1009 Injury, NOS Injuries & Poisonings 1.05 1.01 – 1.09 0.00733 3040 32507 exclusion phecode
1010 Other tests Injuries & Poisonings 1.07 1.02 – 1.12 0.005 2152 23132 exclusion phecode
1011 Complications of surgical and medical procedures Injuries & Poisonings 1.06 1.03 – 1.1 0.00104 3153 35115 exclusion phecode
1012 Late effect Injuries & Poisonings 0.898 0.656 – 1.23 0.502 46 427 exclusion phecode
1013 Asphyxia and hypoxemia Injuries & Poisonings 1.01 0.823 – 1.24 0.918 94 1174 exclusion phecode
1014 Effects of heat, cold and air pressure Injuries & Poisonings 1.1 0.74 – 1.63 0.638 27 273 exclusion phecode
1015 Effects of other external causes Injuries & Poisonings 1.13 1.07 – 1.2 1.44e-05 1374 16745 exclusion phecode
1019
Other ill-defined and unknown causes of
Other ill-defined and unknown causes of morbidity and mortality
 Injuries & Poisonings 1.06 1.04 – 1.09 9.91e-06 5742 62339 exclusion phecode
110 Dermatophytosis / Dermatomycosis Infectious Diseases 1.08 0.875 – 1.33 0.472 91 1032 exclusion phecode
110.1 Dermatophytosis Infectious Diseases 1.08 0.872 – 1.33 0.495 90 999 exclusion phecode
110.11 Dermatophytosis of nail Infectious Diseases 1.25 0.841 – 1.84 0.273 27 281 exclusion phecode
110.12 Althete's foot Infectious Diseases 0.9 0.659 – 1.23 0.506 40 502 exclusion phecode
112 Candidiasis Infectious Diseases 1.15 1.06 – 1.24 0.000572 673 8316 exclusion phecode
117 Mycoses Infectious Diseases 1.14 0.917 – 1.41 0.243 92 1074 exclusion phecode
117.4 Aspergillosis Infectious Diseases 1.01 0.787 – 1.3 0.94 66 628 exclusion phecode
130 Spirochetal infection Infectious Diseases 1.17 0.803 – 1.71 0.41 29 262 exclusion phecode
133 Arthropod-borne diseases Infectious Diseases 1.42 0.938 – 2.14 0.0978 31 254 exclusion phecode
134 Helminthiases Infectious Diseases 1.3 0.957 – 1.77 0.0928 45 539 exclusion phecode
134.1 Intestinal helminthiases Infectious Diseases 1.19 0.853 – 1.65 0.309 38 436 exclusion phecode
136 Other infectious and parasitic diseases Infectious Diseases 1.11 0.897 – 1.38 0.33 90 790 exclusion phecode
145 Cancer of mouth Neoplasms 1.08 0.923 – 1.27 0.332 167 2371 exclusion phecode
145.2 Cancer of tongue Neoplasms 1.13 0.905 – 1.42 0.278 87 1121 exclusion phecode
145.3 Cancer of major salivary glands Neoplasms 0.875 0.626 – 1.22 0.435 38 404 exclusion phecode
145.5 Cancer of the mouth floor Neoplasms 1.21 0.597 – 2.45 0.598 5 201 exclusion phecode
149 Cancer of larynx, pharynx, nasal cavities Neoplasms 1.01 0.843 – 1.21 0.902 121 2266 exclusion phecode
149.1 Cancer of oropharynx Neoplasms 1.01 0.759 – 1.34 0.949 47 962 exclusion phecode
149.4 Cancer of larynx Neoplasms 1.04 0.748 – 1.45 0.817 36 868 exclusion phecode
149.9 Cancer of of nasal cavities Neoplasms 1.11 0.728 – 1.7 0.626 22 196 exclusion phecode
150 Cancer of esophagus Neoplasms 1.07 0.917 – 1.25 0.39 175 2710 exclusion phecode
151 Cancer of stomach Neoplasms 1 0.85 – 1.18 0.991 158 2000 exclusion phecode
153 Colorectal cancer Neoplasms 0.98 0.929 – 1.03 0.453 1522 16806 exclusion phecode
153.2 Colon cancer Neoplasms 0.996 0.934 – 1.06 0.904 1047 11461 exclusion phecode
153.3
Malignant neoplasm of rectum, rectosigmoid
Malignant neoplasm of rectum, rectosigmoid junction, and anus
 Neoplasms 0.976 0.903 – 1.05 0.534 699 7933 exclusion phecode
155 Cancer of liver and intrahepatic bile duct Neoplasms 1.06 0.876 – 1.27 0.566 120 1459 exclusion phecode
155.1 Malignant neoplasm of liver, primary Neoplasms 0.846 0.621 – 1.15 0.289 48 585 exclusion phecode
157 Pancreatic cancer Neoplasms 1.14 0.993 – 1.32 0.0617 223 2531 exclusion phecode
158
Neoplasm of unspecified nature of digestive
Neoplasm of unspecified nature of digestive system
 Neoplasms 0.972 0.867 – 1.09 0.62 343 3933 exclusion phecode
159
Malignant neoplasm of other and ill-defined
Malignant neoplasm of other and ill-defined sites within the digestive organs and peritoneum
 Neoplasms 0.992 0.945 – 1.04 0.755 1833 20591 exclusion phecode
159.2
Malignant neoplasm of small intestine
Malignant neoplasm of small intestine, including duodenum
 Neoplasms 0.849 0.668 – 1.08 0.181 71 687 exclusion phecode
159.3
Malignant neoplasm of gallbladder and
Malignant neoplasm of gallbladder and extrahepatic bile ducts
 Neoplasms 1.01 0.79 – 1.29 0.941 68 799 exclusion phecode
159.4
Malignant neoplasm of retroperitoneum and
Malignant neoplasm of retroperitoneum and peritoneum
 Neoplasms 1.05 0.839 – 1.31 0.688 84 766 exclusion phecode
164 Cancer of intrathoracic organs Neoplasms 0.808 0.51 – 1.28 0.365 22 225 exclusion phecode
165 Cancer within the respiratory system Neoplasms 1.06 0.953 – 1.17 0.295 394 10584 exclusion phecode
165.1 Cancer of bronchus; lung Neoplasms 1 0.883 – 1.14 0.947 245 8453 exclusion phecode
170 Cancer of bone and connective tissue Neoplasms 1.07 0.914 – 1.25 0.402 161 1671 exclusion phecode
170.1 Bone cancer Neoplasms 1.16 0.844 – 1.59 0.363 37 494 exclusion phecode
170.2 Cancer of connective tissue Neoplasms 1.07 0.9 – 1.28 0.435 133 1272 exclusion phecode
172 Skin cancer Neoplasms 0.994 0.965 – 1.02 0.672 5307 50279 exclusion phecode
172.1 Melanomas of skin, dx or hx Neoplasms 1.02 0.955 – 1.08 0.617 1159 10294 exclusion phecode
172.11 Melanomas of skin Neoplasms 1.02 0.961 – 1.09 0.491 1173 10450 exclusion phecode
172.2 Other non-epithelial cancer of skin Neoplasms 0.989 0.958 – 1.02 0.519 4234 40589 exclusion phecode
172.3 Carcinoma in situ of skin Neoplasms 1.01 0.883 – 1.15 0.918 247 2505 exclusion phecode
173 Neoplasm of uncertain behavior of skin Neoplasms 0.888 0.698 – 1.13 0.335 73 773 exclusion phecode
174 Breast cancer Neoplasms 1.02 0.993 – 1.05 0.145 5300 54872 exclusion phecode
174.1 Breast cancer [female] Neoplasms 1.02 0.994 – 1.05 0.119 5232 54081 exclusion phecode
174.11 Malignant neoplasm of female breast Neoplasms 1.02 0.99 – 1.05 0.19 4903 50986 exclusion phecode
174.3 Neoplasm of uncertain behavior of breast Neoplasms 0.891 0.662 – 1.2 0.448 51 490 exclusion phecode
175 Acquired absence of breast Neoplasms 1.02 0.951 – 1.09 0.609 944 10497 exclusion phecode
180 Cervical cancer and dysplasia Neoplasms 1.01 0.944 – 1.09 0.688 846 9684 exclusion phecode
180.1 Cervical cancer Neoplasms 1.02 0.828 – 1.25 0.882 108 1156 exclusion phecode
180.3
Cervical intraepithelial neoplasia [CIN]
Cervical intraepithelial neoplasia [CIN] [Cervical dysplasia]
 Neoplasms 1.01 0.939 – 1.09 0.767 795 9250 exclusion phecode
182 Malignant neoplasm of uterus Neoplasms 1.02 0.937 – 1.11 0.636 621 5471 exclusion phecode
184 Cancer of other female genital organs Neoplasms 1.01 0.926 – 1.1 0.798 589 6068 exclusion phecode
184.1
Malignant neoplasm of ovary and other uterine
Malignant neoplasm of ovary and other uterine adnexa
 Neoplasms 1.03 0.929 – 1.14 0.592 436 4284 exclusion phecode
184.11 Malignant neoplasm of ovary Neoplasms 1.05 0.947 – 1.16 0.352 426 4154 exclusion phecode
184.2
Cancer of other female genital organs
Cancer of other female genital organs (excluding uterus and ovary)
 Neoplasms 0.92 0.75 – 1.13 0.421 110 1305 exclusion phecode
185 Cancer of prostate Neoplasms 1.03 0.979 – 1.08 0.269 1930 17672 exclusion phecode
187 Cancer of other male genital organs Neoplasms 0.938 0.796 – 1.1 0.443 157 1642 exclusion phecode
187.1
Malignant neoplasm of unspecified male genital
Malignant neoplasm of unspecified male genital organ
 Neoplasms 0.945 0.615 – 1.45 0.798 25 230 exclusion phecode
187.2 Malignant neoplasm of testis Neoplasms 0.909 0.747 – 1.11 0.339 108 1089 exclusion phecode
187.8
Neoplasm of uncertain behavior of male genital
Neoplasm of uncertain behavior of male genital organs
 Neoplasms 1.06 0.765 – 1.47 0.722 39 378 exclusion phecode
189
Cancer of urinary organs (incl. kidney and
Cancer of urinary organs (incl. kidney and bladder)
 Neoplasms 1.01 0.946 – 1.07 0.823 1112 14382 exclusion phecode
189.1 Cancer of kidney and renal pelvis Neoplasms 1.05 0.934 – 1.18 0.415 322 3728 exclusion phecode
189.11 Malignant neoplasm of kidney, except pelvis Neoplasms 1.05 0.936 – 1.19 0.387 307 3572 exclusion phecode
189.12 Malignant neoplasm of renal pelvis Neoplasms 0.99 0.643 – 1.52 0.962 22 221 exclusion phecode
189.2 Cancer of bladder Neoplasms 0.924 0.848 – 1.01 0.0735 572 8283 exclusion phecode
189.21 Malignant neoplasm of bladder Neoplasms 0.954 0.869 – 1.05 0.328 482 7337 exclusion phecode
189.4 Malignant neoplasm of other urinary organs Neoplasms 0.92 0.677 – 1.25 0.595 47 482 exclusion phecode
190 Cancer of eye Neoplasms 1.03 0.806 – 1.32 0.798 75 652 exclusion phecode
191
Manlignant and unknown neoplasms of brain and
Manlignant and unknown neoplasms of brain and nervous system
 Neoplasms 1.03 0.902 – 1.18 0.659 251 2591 exclusion phecode
191.1 Cancer of brain and nervous system Neoplasms 0.994 0.859 – 1.15 0.936 209 2114 exclusion phecode
191.11 Cancer of brain Neoplasms 1.04 0.89 – 1.22 0.616 186 1939 exclusion phecode
193 Thyroid cancer Neoplasms 0.957 0.8 – 1.15 0.631 136 1451 exclusion phecode
194 Cancer of other endocrine glands Neoplasms 0.746 0.524 – 1.06 0.105 31 359 exclusion phecode
195 Cancer, suspected or other Neoplasms 1.02 0.995 – 1.05 0.105 5912 62463 exclusion phecode
195.1 Malignant neoplasm, other Neoplasms 1.02 0.993 – 1.05 0.136 5647 59995 exclusion phecode
197 Chemotherapy Neoplasms 1.07 1.04 – 1.09 1.04e-07 7740 84536 exclusion phecode
198 Secondary malignant neoplasm Neoplasms 1.01 0.969 – 1.04 0.781 3219 37209 exclusion phecode
198.1 Secondary malignancy of lymph nodes Neoplasms 0.985 0.939 – 1.03 0.531 1900 21401 exclusion phecode
198.2 Secondary malignancy of respiratory organs Neoplasms 1.01 0.937 – 1.09 0.766 729 8750 exclusion phecode
198.3
Secondary malignant neoplasm of digestive
Secondary malignant neoplasm of digestive systems
 Neoplasms 1.05 0.96 – 1.14 0.303 601 6098 exclusion phecode
198.4 Secondary malignant neoplasm of liver Neoplasms 1.04 0.973 – 1.12 0.232 904 10195 exclusion phecode
198.5 Secondary malignancy of brain/spine Neoplasms 1.11 0.966 – 1.27 0.142 222 3326 exclusion phecode
198.6 Secondary malignancy of bone Neoplasms 1.03 0.954 – 1.12 0.415 667 8166 exclusion phecode
198.7 Secondary malignant neoplasm of skin Neoplasms 1.09 0.851 – 1.4 0.495 68 735 exclusion phecode
199 Neoplasm of uncertain behavior Neoplasms 1.06 0.964 – 1.16 0.237 523 5675 exclusion phecode
199.4 Neurofibromatosis Neoplasms 0.978 0.708 – 1.35 0.894 38 415 exclusion phecode
200 Myeloproliferative disease Neoplasms 1.02 0.912 – 1.15 0.708 325 3723 exclusion phecode
200.1 Polycythemia vera Neoplasms 1.09 0.903 – 1.31 0.376 118 1391 exclusion phecode
201 Hodgkin's disease Neoplasms 1 0.809 – 1.25 0.966 87 1050 exclusion phecode
202 Cancer of other lymphoid, histiocytic tissue Neoplasms 1.02 0.949 – 1.1 0.586 835 8401 exclusion phecode
202.2 Non-Hodgkins lymphoma Neoplasms 0.992 0.915 – 1.08 0.85 666 6726 exclusion phecode
202.21 Nodular lymphoma Neoplasms 1.02 0.859 – 1.21 0.808 152 1391 exclusion phecode
202.24 Large cell lymphoma Neoplasms 0.979 0.854 – 1.12 0.76 236 2197 exclusion phecode
204 Leukemia Neoplasms 1.02 0.932 – 1.11 0.722 589 6010 exclusion phecode
204.1 Lymphoid leukemia Neoplasms 1.03 0.881 – 1.2 0.735 186 2061 exclusion phecode
204.11 Lymphoid leukemia, acute Neoplasms 1 0.672 – 1.49 0.992 23 186 exclusion phecode
204.12 Lymphoid leukemia, chronic Neoplasms 1.02 0.871 – 1.2 0.772 165 1806 exclusion phecode
204.2 Myeloid leukemia Neoplasms 1.01 0.861 – 1.18 0.921 166 1705 exclusion phecode
204.21 Myeloid leukemia, acute Neoplasms 0.96 0.792 – 1.16 0.674 113 1190 exclusion phecode
204.22 Myeloid leukemia, chronic Neoplasms 1.02 0.782 – 1.32 0.906 56 554 exclusion phecode
204.4 Multiple myeloma Neoplasms 0.916 0.792 – 1.06 0.242 198 1981 exclusion phecode
208 Benign neoplasm of colon Neoplasms 1.02 0.989 – 1.04 0.257 6119 72426 exclusion phecode
210 Benign neoplasm of lip, oral cavity, and pharynx Neoplasms 1.06 0.94 – 1.18 0.36 324 3798 exclusion phecode
211
Benign neoplasm of other parts of digestive
Benign neoplasm of other parts of digestive system
 Neoplasms 1.05 1 – 1.1 0.0408 2251 20415 exclusion phecode
212
Benign neoplasm of respiratory and
Benign neoplasm of respiratory and intrathoracic organs
 Neoplasms 1.2 0.989 – 1.45 0.0645 116 1317 exclusion phecode
213 Benign neoplasm of bone and articular cartilage Neoplasms 1.01 0.833 – 1.22 0.944 119 1267 exclusion phecode
214 Lipoma Neoplasms 1.09 1.05 – 1.14 7.46e-05 2214 23879 exclusion phecode
214.1 Lipoma of skin and subcutaneous tissue Neoplasms 1.11 1.06 – 1.17 3.68e-05 1650 17881 exclusion phecode
215
Other benign neoplasm of connective and other
Other benign neoplasm of connective and other soft tissue
 Neoplasms 1.14 1.03 – 1.26 0.0088 427 4424 exclusion phecode
216 Benign neoplasm of skin Neoplasms 1.02 0.986 – 1.06 0.212 3109 30604 exclusion phecode
217 Vascular hamartomas and non-neoplastic nevi Neoplasms 1.03 0.899 – 1.19 0.636 216 2471 exclusion phecode
217.1 Nevus, non-neoplastic Neoplasms 1.04 0.896 – 1.2 0.63 207 2282 exclusion phecode
218 Benign neoplasm of uterus Neoplasms 1.04 1.01 – 1.08 0.00985 4555 44195 exclusion phecode
218.1 Uterine leiomyoma Neoplasms 1.03 1 – 1.07 0.0375 4633 45030 exclusion phecode
218.2 Other benign neoplasm of uterus Neoplasms 1.06 0.896 – 1.25 0.503 164 1490 exclusion phecode
220 Benign neoplasm of ovary Neoplasms 1.02 0.935 – 1.11 0.682 612 6346 exclusion phecode
221 Benign neoplasm of other female genital organs Neoplasms 1 0.812 – 1.24 0.984 96 997 exclusion phecode
222 Benign neoplasm of male genital organs Neoplasms 0.851 0.647 – 1.12 0.247 58 521 exclusion phecode
223
Benign neoplasm of kidney and other urinary
Benign neoplasm of kidney and other urinary organs
 Neoplasms 0.833 0.623 – 1.11 0.218 47 633 exclusion phecode
224 Benign neoplasm of eye Neoplasms 0.972 0.725 – 1.3 0.847 50 505 exclusion phecode
224.1 Benign neoplasm of eye, uveal Neoplasms 1.29 0.854 – 1.94 0.227 24 249 exclusion phecode
225
Benign neoplasm of brain and other parts of
Benign neoplasm of brain and other parts of nervous system
 Neoplasms 0.999 0.89 – 1.12 0.986 343 3244 exclusion phecode
225.1
Benign neoplasm of brain, cranial nerves
Benign neoplasm of brain, cranial nerves, meninges
 Neoplasms 0.988 0.877 – 1.11 0.849 317 3067 exclusion phecode
225.2 Benign neoplasm of spinal cord, meninges Neoplasms 1.08 0.73 – 1.6 0.699 30 267 exclusion phecode
226 Benign neoplasm of thyroid glands Neoplasms 0.938 0.778 – 1.13 0.505 127 1107 exclusion phecode
227
Benign neoplasm of other endocrine glands and
Benign neoplasm of other endocrine glands and related structures
 Neoplasms 1.02 0.911 – 1.15 0.713 333 3441 exclusion phecode
227.1 Benign neoplasm of adrenal gland Neoplasms 0.926 0.69 – 1.24 0.609 46 733 exclusion phecode
227.2 Benign neoplasm of parathyroid gland Neoplasms 0.897 0.758 – 1.06 0.208 152 1532 exclusion phecode
227.3
Benign neoplasm of pituitary gland and
Benign neoplasm of pituitary gland and craniopharyngeal duct (pouch)
 Neoplasms 1.26 1.05 – 1.51 0.0151 135 1220 exclusion phecode
228 Hemangioma and lymphangioma, any site Neoplasms 0.962 0.883 – 1.05 0.374 609 6262 exclusion phecode
229 Benign neoplasm of unspecified sites Neoplasms 1.05 0.983 – 1.13 0.145 964 9633 exclusion phecode
240 Simple and unspecified goiter Endocrine/metabolic 1.02 0.895 – 1.16 0.795 257 2549 exclusion phecode
241 Nontoxic nodular goiter Endocrine/metabolic 1.02 0.923 – 1.12 0.745 468 4632 exclusion phecode
241.1 Nontoxic uninodular goiter Endocrine/metabolic 0.951 0.818 – 1.11 0.519 191 1943 exclusion phecode
241.2 Nontoxic multinodular goiter Endocrine/metabolic 1.04 0.918 – 1.17 0.558 288 2851 exclusion phecode
242 Thyrotoxicosis with or without goiter Endocrine/metabolic 1 0.924 – 1.09 0.929 650 7632 exclusion phecode
242.1 Graves' disease Endocrine/metabolic 1.01 0.85 – 1.21 0.887 138 1899 exclusion phecode
242.2 Toxic multinodular goiter Endocrine/metabolic 0.937 0.666 – 1.32 0.709 34 367 exclusion phecode
242.3 Exophthalmos Endocrine/metabolic 1.1 0.803 – 1.52 0.541 39 556 exclusion phecode
244 Hypothyroidism Endocrine/metabolic 1.09 1.06 – 1.13 2.32e-10 5674 60173 exclusion phecode
244.1 Secondary hypothyroidism Endocrine/metabolic 1.07 0.965 – 1.18 0.208 435 4614 exclusion phecode
244.2 Acquired hypothyroidism Endocrine/metabolic 1.01 0.724 – 1.42 0.936 39 407 exclusion phecode
244.4 Hypothyroidism NOS Endocrine/metabolic 1.1 1.07 – 1.13 1.25e-10 5412 57706 exclusion phecode
245 Thyroiditis Endocrine/metabolic 1.03 0.857 – 1.24 0.737 132 1215 exclusion phecode
245.2 Chronic thyroiditis Endocrine/metabolic 1.09 0.883 – 1.35 0.419 102 945 exclusion phecode
245.21 Chronic lymphocytic thyroiditis Endocrine/metabolic 1.08 0.866 – 1.35 0.492 97 912 exclusion phecode
246 Other disorders of thyroid Endocrine/metabolic 1.17 0.99 – 1.38 0.0656 165 1670 exclusion phecode
250 Diabetes mellitus Endocrine/metabolic 1.11 1.08 – 1.14 3.07e-15 6268 70032 exclusion phecode
250.1 Type 1 diabetes Endocrine/metabolic 1.1 1.02 – 1.17 0.00883 944 10431 exclusion phecode
250.11 Type 1 diabetes with ketoacidosis Endocrine/metabolic 1.1 0.889 – 1.35 0.388 93 973 exclusion phecode
250.12 Type 1 diabetes with renal manifestations Endocrine/metabolic 0.918 0.617 – 1.37 0.673 25 311 exclusion phecode
250.13 Type 1 diabetes with ophthalmic manifestations Endocrine/metabolic 1.13 0.965 – 1.33 0.127 167 1846 exclusion phecode
250.14 Type 1 diabetes with neurological manifestations Endocrine/metabolic 1.02 0.771 – 1.35 0.896 53 630 exclusion phecode
250.2 Type 2 diabetes Endocrine/metabolic 1.12 1.09 – 1.15 1e-15 5550 63639 exclusion phecode
250.21 Type 2 diabetes with ketoacidosis Endocrine/metabolic 0.925 0.675 – 1.27 0.628 42 396 exclusion phecode
250.22 Type 2 diabetes with renal manifestations Endocrine/metabolic 1.18 0.913 – 1.52 0.207 63 715 exclusion phecode
250.23 Type 2 diabetes with ophthalmic manifestations Endocrine/metabolic 1.19 1.06 – 1.33 0.00412 322 3629 exclusion phecode
250.24 Type 2 diabetes with neurological manifestations Endocrine/metabolic 1.14 0.967 – 1.34 0.12 161 1838 exclusion phecode
250.4 Abnormal glucose Endocrine/metabolic 0.995 0.868 – 1.14 0.945 231 2664 exclusion phecode
250.41 Impaired fasting glucose Endocrine/metabolic 0.962 0.774 – 1.19 0.724 95 1012 exclusion phecode
250.42 Other abnormal glucose Endocrine/metabolic 0.983 0.825 – 1.17 0.85 135 1665 exclusion phecode
250.5 Glycosuria or Acetonuria Endocrine/metabolic 1.14 0.883 – 1.48 0.306 59 535 exclusion phecode
250.6 Polyneuropathy in diabetes Endocrine/metabolic 1.19 0.981 – 1.44 0.0787 113 1278 exclusion phecode
250.7 Diabetic retinopathy Endocrine/metabolic 1.14 1.04 – 1.26 0.00803 455 4880 exclusion phecode
251.1 Hypoglycemia Endocrine/metabolic 1.13 1 – 1.26 0.044 320 3507 exclusion phecode
252 Disorders of parathyroid gland Endocrine/metabolic 1.02 0.911 – 1.13 0.772 359 3508 exclusion phecode
252.1 Hyperparathyroidism Endocrine/metabolic 1 0.891 – 1.13 0.977 320 3129 exclusion phecode
252.2 Hypoparathyroidism Endocrine/metabolic 0.998 0.779 – 1.28 0.989 62 581 exclusion phecode
253
Disorders of the pituitary gland and its
Disorders of the pituitary gland and its hypothalamic control
 Endocrine/metabolic 1.09 0.962 – 1.24 0.172 262 2561 exclusion phecode
253.1 Pituitary hyperfunction Endocrine/metabolic 1.05 0.827 – 1.33 0.703 75 702 exclusion phecode
253.11 Acromegaly and gigantism Endocrine/metabolic 0.803 0.56 – 1.15 0.233 34 367 exclusion phecode
253.2 Pituitary hypofunction Endocrine/metabolic 1.13 0.916 – 1.38 0.26 103 949 exclusion phecode
253.3 Diabetes insipidus Endocrine/metabolic 1.15 0.829 – 1.58 0.411 40 390 exclusion phecode
253.7 Other disorders of neurohypophysis Endocrine/metabolic 1.01 0.762 – 1.34 0.937 51 598 exclusion phecode
255 Disorders of adrenal glands Endocrine/metabolic 1.08 0.946 – 1.24 0.244 239 2564 exclusion phecode
255.1 Adrenal hyperfunction Endocrine/metabolic 1.15 0.908 – 1.46 0.245 71 767 exclusion phecode
255.11 Cushing's syndrome Endocrine/metabolic 1.26 0.933 – 1.71 0.131 40 466 exclusion phecode
255.12 Hyperaldosteronism Endocrine/metabolic 0.881 0.612 – 1.27 0.494 32 296 exclusion phecode
255.2 Adrenal hypofunction Endocrine/metabolic 1.08 0.906 – 1.3 0.377 147 1442 exclusion phecode
255.21 Glucocorticoid deficiency Endocrine/metabolic 1.09 0.91 – 1.31 0.35 146 1438 exclusion phecode
256 Ovarian dysfunction Endocrine/metabolic 0.953 0.795 – 1.14 0.608 127 1088 exclusion phecode
256.4 Polycystic ovaries Endocrine/metabolic 0.929 0.764 – 1.13 0.459 111 958 exclusion phecode
257 Testicular dysfunction Endocrine/metabolic 1.18 0.91 – 1.54 0.208 58 568 exclusion phecode
257.1 Testicular hypofunction Endocrine/metabolic 1.13 0.868 – 1.48 0.354 54 538 exclusion phecode
258 Iatrogenic endocrine disorders Endocrine/metabolic 1.32 0.955 – 1.82 0.0932 41 379 exclusion phecode
259 Other endocrine disorders Endocrine/metabolic 1.09 0.819 – 1.44 0.563 55 588 exclusion phecode
260 Protein-calorie malnutrition Endocrine/metabolic 0.983 0.756 – 1.28 0.897 58 782 exclusion phecode
260.1 Cachexia Endocrine/metabolic 0.964 0.56 – 1.66 0.895 12 189 exclusion phecode
260.6 Anorexia Endocrine/metabolic 1.18 1.04 – 1.33 0.0102 290 3133 exclusion phecode
261 Vitamin deficiency Endocrine/metabolic 1.08 0.976 – 1.2 0.137 425 4688 exclusion phecode
261.2 Vitamin B-complex deficiencies Endocrine/metabolic 1.11 0.97 – 1.27 0.13 242 2875 exclusion phecode
261.4 Vitamin D deficiency Endocrine/metabolic 1.02 0.872 – 1.19 0.821 189 1804 exclusion phecode
261.41 Rickets or osteomalacia Endocrine/metabolic 1.2 0.85 – 1.69 0.301 37 297 exclusion phecode
262 Mineral deficiency NEC Endocrine/metabolic 0.87 0.699 – 1.08 0.211 100 959 exclusion phecode
269 Proteinuria Endocrine/metabolic 1.08 0.883 – 1.32 0.449 100 1298 exclusion phecode
270
Disorders of protein plasma/amino-acid
Disorders of protein plasma/amino-acid transport and metabolism
 Endocrine/metabolic 1.38 1.11 – 1.71 0.0035 103 1089 exclusion phecode
270.3 Disorders of plasma protein metabolism Endocrine/metabolic 1.3 1.04 – 1.63 0.0238 91 903 exclusion phecode
270.32 Paraproteinemia Endocrine/metabolic 1.36 1.02 – 1.81 0.0333 61 659 exclusion phecode
270.33 Amyloidosis Endocrine/metabolic 1.21 0.884 – 1.65 0.238 44 412 exclusion phecode
270.35 Macroglobulinemia Endocrine/metabolic 1.12 0.764 – 1.65 0.554 34 268 exclusion phecode
271
Disorders of carbohydrate transport and
Disorders of carbohydrate transport and metabolism
 Endocrine/metabolic 1.05 0.811 – 1.35 0.733 65 618 exclusion phecode
271.3
Intestinal disaccharidase deficiencies and
Intestinal disaccharidase deficiencies and disaccharide malabsorption
 Endocrine/metabolic 1.03 0.778 – 1.36 0.846 55 538 exclusion phecode
272 Disorders of lipoid metabolism Endocrine/metabolic 1.09 1.07 – 1.11 1.24e-16 10844 91455 exclusion phecode
272.1 Hyperlipidemia Endocrine/metabolic 1.09 1.07 – 1.11 2.06e-16 10818 91373 exclusion phecode
272.11 Hypercholesterolemia Endocrine/metabolic 1.09 1.06 – 1.11 1.18e-14 10034 88404 exclusion phecode
272.12 Hyperglyceridemia Endocrine/metabolic 1.03 0.656 – 1.61 0.902 18 201 exclusion phecode
272.13 Mixed hyperlipidemia Endocrine/metabolic 1.05 0.789 – 1.41 0.727 47 617 exclusion phecode
272.9 Unspecified disorder of lipoid metabolism Endocrine/metabolic 1.11 0.864 – 1.43 0.408 61 761 exclusion phecode
274 Gout and other crystal arthropathies Endocrine/metabolic 1.25 1.18 – 1.33 2.25e-12 1106 13015 exclusion phecode
274.1 Gout Endocrine/metabolic 1.27 1.18 – 1.36 1.42e-11 903 10878 exclusion phecode
274.11 Gouty arthropathy Endocrine/metabolic 1.26 0.943 – 1.69 0.118 44 394 exclusion phecode
274.2 Crystal arthropathies Endocrine/metabolic 1.19 1.04 – 1.37 0.011 226 2322 exclusion phecode
274.21 Chondrocalcinosis Endocrine/metabolic 1.18 1.02 – 1.37 0.0258 198 2137 exclusion phecode
275 Disorders of mineral metabolism Endocrine/metabolic 1.08 0.997 – 1.16 0.0602 701 7960 exclusion phecode
275.1 Disorders of iron metabolism Hematopoietic 1.13 0.978 – 1.3 0.0975 212 2352 exclusion phecode
275.3 Disorders of magnesium metabolism Endocrine/metabolic 1.08 0.895 – 1.31 0.414 120 1408 exclusion phecode
275.5 Disorders of calcium/phosphorus metabolism Endocrine/metabolic 1.08 0.973 – 1.19 0.154 403 4653 exclusion phecode
275.53 Disorders of phosphorus metabolism Endocrine/metabolic 1.29 0.998 – 1.66 0.0522 60 669 exclusion phecode
276
Disorders of fluid, electrolyte, and acid-base
Disorders of fluid, electrolyte, and acid-base balance
 Endocrine/metabolic 1.04 0.999 – 1.09 0.0577 2361 27695 exclusion phecode
276.1 Electrolyte imbalance Endocrine/metabolic 1.01 0.955 – 1.07 0.704 1336 15500 exclusion phecode
276.11 Hyperosmolality and/or hypernatremia Endocrine/metabolic 0.854 0.676 – 1.08 0.188 77 907 exclusion phecode
276.12 Hyposmolality and/or hyponatremia Endocrine/metabolic 1.02 0.941 – 1.11 0.586 606 6930 exclusion phecode
276.13 Hyperpotassemia Endocrine/metabolic 1.11 0.982 – 1.25 0.0959 297 3489 exclusion phecode
276.14 Hypopotassemia Endocrine/metabolic 0.964 0.878 – 1.06 0.447 476 5620 exclusion phecode
276.4 Acid-base balance disorder Endocrine/metabolic 1.1 0.98 – 1.23 0.105 326 4421 exclusion phecode
276.41 Acidosis Endocrine/metabolic 1.09 0.971 – 1.23 0.14 294 3993 exclusion phecode
276.42 Alkalosis Endocrine/metabolic 1.02 0.712 – 1.46 0.912 34 426 exclusion phecode
276.5 Hypovolemia Endocrine/metabolic 1.06 0.991 – 1.14 0.0904 939 10721 exclusion phecode
276.6 Fluid overload Endocrine/metabolic 1.07 0.903 – 1.26 0.443 147 1687 exclusion phecode
276.8 Polydipsia Endocrine/metabolic 1.18 0.89 – 1.56 0.251 47 531 exclusion phecode
277 Other disorders of metabolism Endocrine/metabolic 1.07 0.949 – 1.2 0.27 306 3440 exclusion phecode
277.4 Disorders of bilirubin excretion Endocrine/metabolic 1.06 0.899 – 1.26 0.475 163 1314 exclusion phecode
277.5 Other disorders of lipoid metabolism Endocrine/metabolic 1.1 0.858 – 1.4 0.463 70 840 exclusion phecode
277.51 Lipoprotein disorders Endocrine/metabolic 0.872 0.484 – 1.57 0.649 11 196 exclusion phecode
278 Overweight, obesity and other hyperalimentation Endocrine/metabolic 1.19 1.15 – 1.23 2.87e-23 3679 42786 exclusion phecode
278.1 Obesity Endocrine/metabolic 1.19 1.15 – 1.24 1.3e-23 3617 42120 exclusion phecode
278.3 Localized adiposity Endocrine/metabolic 0.994 0.714 – 1.38 0.974 30 363 exclusion phecode
278.4 Abnormal weight gain Endocrine/metabolic 0.868 0.594 – 1.27 0.463 27 286 exclusion phecode
279 Disorders involving the immune mechanism Endocrine/metabolic 1.03 0.826 – 1.27 0.819 92 948 exclusion phecode
279.1 Immunity deficiency Endocrine/metabolic 1.03 0.813 – 1.29 0.834 80 801 exclusion phecode
279.11 Deficiency of humoral immunity Endocrine/metabolic 0.88 0.661 – 1.17 0.379 50 536 exclusion phecode
279.7 Other immunological findings Endocrine/metabolic 1.17 0.941 – 1.45 0.16 95 825 exclusion phecode
280 Iron deficiency anemias Hematopoietic 1.06 1.03 – 1.11 0.00124 3027 30054 exclusion phecode
280.1
Iron deficiency anemias, unspecified or not due
Iron deficiency anemias, unspecified or not due to blood loss
 Hematopoietic 1.07 1.03 – 1.11 0.00102 2917 28847 exclusion phecode
280.2
Iron deficiency anemia secondary to blood loss
Iron deficiency anemia secondary to blood loss (chronic)
 Hematopoietic 0.991 0.848 – 1.16 0.913 184 1859 exclusion phecode
281 Other deficiency anemia Hematopoietic 1.11 0.997 – 1.23 0.0566 404 4412 exclusion phecode
281.1 Megaloblastic anemia Hematopoietic 1.1 0.991 – 1.22 0.0726 391 4242 exclusion phecode
281.11 Pernicious anemia Hematopoietic 1.14 1.01 – 1.29 0.0358 280 2994 exclusion phecode
281.12 Other vitamin B12 deficiency anemia Hematopoietic 0.934 0.73 – 1.2 0.588 72 736 exclusion phecode
281.13 Folate-deficiency anemia Hematopoietic 1.21 0.922 – 1.6 0.167 59 656 exclusion phecode
281.9 Deficiency anemias Hematopoietic 1.1 0.688 – 1.76 0.692 19 199 exclusion phecode
282 Hereditary hemolytic anemias Hematopoietic 1.18 0.894 – 1.55 0.245 57 593 exclusion phecode
282.8 Other hemoglobinopathies Hematopoietic 1 0.644 – 1.55 0.999 19 214 exclusion phecode
282.9 Other hereditary hemolytic anemias Hematopoietic 1.25 0.891 – 1.76 0.195 34 354 exclusion phecode
283 Acquired hemolytic anemias Hematopoietic 1.12 0.844 – 1.48 0.439 54 525 exclusion phecode
283.1 Autoimmune hemolytic anemias Hematopoietic 1.25 0.918 – 1.7 0.158 45 416 exclusion phecode
284 Aplastic anemia Hematopoietic 1.19 1 – 1.41 0.0462 145 1611 exclusion phecode
285 Other anemias Hematopoietic 1.05 1.01 – 1.08 0.00497 4529 47293 exclusion phecode
285.1 Acute posthemorrhagic anemia Hematopoietic 1.13 0.93 – 1.38 0.214 109 1087 exclusion phecode
285.2 Anemia of chronic disease Hematopoietic 1.14 0.994 – 1.3 0.061 248 2696 exclusion phecode
285.22 Anemia in neoplastic disease Hematopoietic 1.13 0.952 – 1.33 0.165 160 1625 exclusion phecode
286 Coagulation defects Hematopoietic 1.06 0.949 – 1.19 0.287 335 3627 exclusion phecode
286.1 Congenital coagulation defects Hematopoietic 1.17 1 – 1.37 0.045 176 1862 exclusion phecode
286.11 Von willebrand's disease Hematopoietic 1.18 0.855 – 1.62 0.317 39 380 exclusion phecode
286.12
Congenital deficiency of other clotting factors
Congenital deficiency of other clotting factors (including factor VII)
 Hematopoietic 1.22 1 – 1.5 0.0466 113 1229 exclusion phecode
286.13 Congenital factor VIII disorder Hematopoietic 1.09 0.694 – 1.72 0.702 19 260 exclusion phecode
286.5
Hemorrhagic disorder due to intrinsic
Hemorrhagic disorder due to intrinsic circulating anticoagulants
 Hematopoietic 1.1 0.747 – 1.62 0.631 25 325 exclusion phecode
286.7 Other and unspecified coagulation defects Hematopoietic 1.03 0.865 – 1.23 0.737 143 1531 exclusion phecode
287 Purpura and other hemorrhagic conditions Hematopoietic 1.03 0.95 – 1.13 0.433 595 6153 exclusion phecode
287.1 Spontaneous ecchymoses Hematopoietic 0.989 0.734 – 1.33 0.944 54 504 exclusion phecode
287.2 Allergic purpura Hematopoietic 1 0.643 – 1.56 1 20 195 exclusion phecode
287.3 Thrombocytopenia Hematopoietic 1.05 0.964 – 1.15 0.251 562 5764 exclusion phecode
287.31 Primary thrombocytopenia Hematopoietic 0.983 0.831 – 1.16 0.845 157 1605 exclusion phecode
287.32 Secondary thrombocytopenia Hematopoietic 0.723 0.481 – 1.09 0.119 26 288 exclusion phecode
288 Diseases of white blood cells Hematopoietic 0.97 0.917 – 1.03 0.278 1422 14614 exclusion phecode
288.1 Decreased white blood cell count Hematopoietic 0.976 0.919 – 1.04 0.436 1210 12307 exclusion phecode
288.11 Neutropenia Hematopoietic 0.977 0.92 – 1.04 0.454 1214 12337 exclusion phecode
288.3 Eosinophilia Hematopoietic 0.633 0.42 – 0.954 0.0289 29 270 exclusion phecode
289 Other diseases of blood and blood-forming organs Hematopoietic 1.09 0.966 – 1.22 0.167 304 3229 exclusion phecode
289.3
Personal history of diseases of blood and
Personal history of diseases of blood and blood-forming organs
 Hematopoietic 0.953 0.792 – 1.14 0.605 119 1113 exclusion phecode
289.4 Lymphadenitis Hematopoietic 1.11 1.03 – 1.19 0.0051 873 10116 exclusion phecode
289.5 Diseases of spleen Hematopoietic 0.927 0.795 – 1.08 0.332 172 1935 exclusion phecode
289.8 Polycythemia, secondary Hematopoietic 1.26 1 – 1.6 0.0485 75 1043 exclusion phecode
289.9 Abnormality of red blood cells Hematopoietic 1.5 0.989 – 2.27 0.0564 25 325 exclusion phecode
290
Delirium dementia and amnestic and other
Delirium dementia and amnestic and other cognitive disorders
 Mental Disorders 1.08 0.991 – 1.17 0.0819 602 6883 exclusion phecode
290.1 Dementias Mental Disorders 1.06 0.952 – 1.19 0.276 345 3512 exclusion phecode
290.11 Alzheimer's disease Mental Disorders 0.993 0.839 – 1.17 0.933 146 1551 exclusion phecode
290.16 Vascular dementia Mental Disorders 1.16 0.906 – 1.49 0.236 63 659 exclusion phecode
290.2 Delirium due to conditions classified elsewhere Mental Disorders 1.14 0.979 – 1.33 0.092 188 2302 exclusion phecode
290.3
Other persistent mental disorders due to
Other persistent mental disorders due to conditions classified elsewhere
 Mental Disorders 1.51 0.842 – 2.72 0.166 14 277 exclusion phecode
291
Other specified nonpsychotic and/or transient
Other specified nonpsychotic and/or transient mental disorders
 Mental Disorders 1.15 1.02 – 1.3 0.0281 282 3225 exclusion phecode
291.1
Transient mental disorders due to conditions
Transient mental disorders due to conditions classified elsewhere
 Mental Disorders 0.845 0.607 – 1.18 0.321 41 551 exclusion phecode
291.4
Specific nonpsychotic mental disorders due to
Specific nonpsychotic mental disorders due to brain damage
 Mental Disorders 1.05 0.848 – 1.31 0.631 95 1098 exclusion phecode
291.8 Alteration of consciousness Mental Disorders 1.25 1.06 – 1.47 0.0078 153 1638 exclusion phecode
292 Neurological disorders Mental Disorders 1.04 0.984 – 1.09 0.177 1554 17349 exclusion phecode
292.1 Aphasia/speech disturbance Mental Disorders 0.996 0.908 – 1.09 0.927 502 5692 exclusion phecode
292.2 Mild cognitive impairment Mental Disorders 1.05 0.817 – 1.36 0.686 64 701 exclusion phecode
292.3 Memory loss Mental Disorders 1.08 0.945 – 1.23 0.265 254 2646 exclusion phecode
292.4 Altered mental status Mental Disorders 1.07 0.992 – 1.16 0.0783 711 7984 exclusion phecode
292.6 Hallucinations Mental Disorders 0.969 0.796 – 1.18 0.755 115 1169 exclusion phecode
293 Symptoms involving head and neck Mental Disorders 1.11 1.03 – 1.21 0.00952 641 7752 exclusion phecode
293.1
Swelling, mass, or lump in head and neck
Swelling, mass, or lump in head and neck [Space-occupying lesion, intracranial NOS]
 Mental Disorders 1.08 0.963 – 1.21 0.186 324 3545 exclusion phecode
295 Schizophrenia and other psychotic disorders Mental Disorders 1.01 0.884 – 1.16 0.844 237 3517 exclusion phecode
295.1 Schizophrenia Mental Disorders 0.898 0.758 – 1.06 0.216 150 2342 exclusion phecode
295.2 Paranoid disorders Mental Disorders 1.15 0.874 – 1.51 0.318 61 747 exclusion phecode
295.3 Psychosis Mental Disorders 1.13 0.855 – 1.5 0.385 56 734 exclusion phecode
296 Mood disorders Mental Disorders 1.1 1.07 – 1.14 6.03e-09 4031 53381 exclusion phecode
296.1 Bipolar Mental Disorders 1.05 0.928 – 1.18 0.465 318 4506 exclusion phecode
296.2 Depression Mental Disorders 1.12 1.08 – 1.15 1.55e-10 3845 50779 exclusion phecode
296.22 Major depressive disorder Mental Disorders 1.07 0.895 – 1.29 0.444 130 1508 exclusion phecode
297.2 Suicide or self-inflicted injury Mental Disorders 1.05 0.832 – 1.32 0.684 81 1358 exclusion phecode
300 Anxiety disorders Mental Disorders 1.07 1.03 – 1.12 0.00103 2456 29389 exclusion phecode
300.1 Anxiety disorder Mental Disorders 1.08 1.03 – 1.13 0.000631 2291 27155 exclusion phecode
300.11 Generalized anxiety disorder Mental Disorders 0.981 0.759 – 1.27 0.884 67 648 exclusion phecode
300.12 Agorophobia, social phobia, and panic disorder Mental Disorders 1.09 0.959 – 1.24 0.182 255 3058 exclusion phecode
300.13 Phobia Mental Disorders 1.07 0.921 – 1.25 0.358 180 2181 exclusion phecode
300.3 Obsessive-compulsive disorders Mental Disorders 0.923 0.71 – 1.2 0.55 57 578 exclusion phecode
300.4 Dysthymic disorder Mental Disorders 1.48 0.872 – 2.5 0.147 19 217 exclusion phecode
300.8 Acute reaction to stress Mental Disorders 0.936 0.683 – 1.28 0.68 40 531 exclusion phecode
300.9 Posttraumatic stress disorder Mental Disorders 0.971 0.694 – 1.36 0.864 32 489 exclusion phecode
301 Personality disorders Mental Disorders 1.16 0.941 – 1.43 0.163 95 1468 exclusion phecode
301.2 Antisocial/borderline personality disorder Mental Disorders 1.03 0.728 – 1.46 0.862 35 523 exclusion phecode
302 Sexual and gender identity disorders Mental Disorders 1.15 0.905 – 1.47 0.246 68 1069 exclusion phecode
303 Psychogenic and somatoform disorders Mental Disorders 1.06 0.91 – 1.22 0.474 188 1997 exclusion phecode
303.3 Psychogenic disorder Mental Disorders 1.02 0.856 – 1.22 0.81 134 1503 exclusion phecode
303.4 Somatoform disorder Mental Disorders 1.07 0.81 – 1.42 0.631 54 542 exclusion phecode
304 Adjustment reaction Mental Disorders 1.32 1.06 – 1.63 0.0114 104 1310 exclusion phecode
305.2 Eating disorder Mental Disorders 0.886 0.646 – 1.22 0.452 47 403 exclusion phecode
306 Other mental disorder Mental Disorders 1.17 1.11 – 1.23 2.97e-08 1326 94770 exclusion phecode
306.9 Tension headache Mental Disorders 1.03 0.855 – 1.23 0.776 119 1378 exclusion phecode
313 Pervasive developmental disorders Mental Disorders 0.937 0.658 – 1.34 0.719 31 280 exclusion phecode
313.3 Autism Mental Disorders 0.938 0.614 – 1.43 0.766 22 193 exclusion phecode
315 Develomental delays and disorders Mental Disorders 1.04 0.853 – 1.28 0.677 108 1311 exclusion phecode
315.1 Learning disorder Mental Disorders 1.34 1.06 – 1.7 0.0142 79 629 exclusion phecode
315.2 Speech and language disorder Mental Disorders 1.2 0.751 – 1.93 0.442 19 302 exclusion phecode
316 Substance addiction and disorders Mental Disorders 1.14 1.07 – 1.22 4.26e-05 1035 21290 exclusion phecode
316.1 Polyneuropathy due to drugs Mental Disorders 0.951 0.628 – 1.44 0.812 20 230 exclusion phecode
317 Alcohol-related disorders Mental Disorders 1.1 1.06 – 1.14 1.39e-06 3092 50473 exclusion phecode
317.1 Alcoholism Mental Disorders 1.07 1.03 – 1.12 0.00102 2291 35291 exclusion phecode
317.11 Alcoholic liver damage Mental Disorders 1.13 0.969 – 1.32 0.12 180 3312 exclusion phecode
318 Tobacco use disorder Mental Disorders 1.08 0.988 – 1.17 0.0926 543 76332 exclusion phecode
320 Meningitis Neurological 1.02 0.876 – 1.2 0.765 178 1778 exclusion phecode
323 Encephalitis Neurological 1.02 0.849 – 1.24 0.798 125 1352 exclusion phecode
323.2 Acute (transverse) myelitis Neurological 0.654 0.444 – 0.965 0.0323 27 303 exclusion phecode
324 Other CNS infection and poliomyelitis Neurological 0.91 0.744 – 1.11 0.36 107 1158 exclusion phecode
327 Sleep disorders Neurological 1.09 0.984 – 1.22 0.0984 377 4381 exclusion phecode
327.3 Sleep apnea Neurological 1.12 1.06 – 1.18 6.29e-05 1390 16291 exclusion phecode
327.4 Insomnia Neurological 1.12 0.844 – 1.48 0.437 52 618 exclusion phecode
327.41 Organic or persistent insomnia Neurological 1.14 0.849 – 1.53 0.383 43 524 exclusion phecode
331 Other cerebral degenerations Neurological 1.13 1.02 – 1.26 0.0165 407 4192 exclusion phecode
331.1 Hydrocephalus Neurological 1.11 0.956 – 1.29 0.166 179 1902 exclusion phecode
331.9 Cerebral degeneration, unspecified Neurological 1.15 0.971 – 1.36 0.105 147 1548 exclusion phecode
332 Parkinson's disease Neurological 1.01 0.919 – 1.12 0.798 483 3973 exclusion phecode
333
Extrapyramidal disease and abnormal movement
Extrapyramidal disease and abnormal movement disorders
 Neurological 1.07 0.958 – 1.2 0.225 341 3533 exclusion phecode
333.1 Essential tremor Neurological 1.1 0.867 – 1.39 0.44 76 871 exclusion phecode
333.2 Myoclonus Neurological 1.25 0.895 – 1.73 0.193 36 379 exclusion phecode
333.4 Torsion dystonia Neurological 1.04 0.854 – 1.26 0.71 111 1006 exclusion phecode
334 Degenerative disease of the spinal cord Neurological 1.1 1.01 – 1.2 0.0255 593 6753 exclusion phecode
334.1 Spinocerebellar disease Neurological 1.06 0.799 – 1.39 0.705 50 423 exclusion phecode
334.2 Anterior horn cell disease Neurological 0.977 0.792 – 1.2 0.825 96 860 exclusion phecode
335 Multiple sclerosis Neurological 0.944 0.857 – 1.04 0.241 473 5596 exclusion phecode
337 Disorders of the autonomic nervous system Neurological 1.03 0.845 – 1.26 0.758 103 1004 exclusion phecode
337.1 Peripheral autonomic neuropathy Neurological 1.1 0.772 – 1.58 0.592 30 269 exclusion phecode
338 Pain Neurological 1.19 1.04 – 1.35 0.0107 260 3028 exclusion phecode
338.1 Acute pain Neurological 1.11 0.933 – 1.33 0.234 143 1507 exclusion phecode
338.2 Chronic pain Neurological 1.24 1.03 – 1.51 0.025 118 1561 exclusion phecode
339 Other headache syndromes Neurological 1.1 1.06 – 1.14 7.77e-07 2976 31811 exclusion phecode
340 Migraine Neurological 1.02 0.96 – 1.08 0.522 1207 11984 exclusion phecode
340.1 Migrain with aura Neurological 1.15 0.916 – 1.46 0.223 90 905 exclusion phecode
341
Other demyelinating diseases of central nervous
Other demyelinating diseases of central nervous system
 Neurological 0.974 0.765 – 1.24 0.828 74 1089 exclusion phecode
342 Hemiplegia Neurological 1.04 0.944 – 1.14 0.442 471 5556 exclusion phecode
343 Infantile cerebral palsy Neurological 1.1 0.868 – 1.4 0.418 79 597 exclusion phecode
344 Other paralytic syndromes Neurological 1.09 0.946 – 1.26 0.231 213 2545 exclusion phecode
345 Epilepsy, recurrent seizures, convulsions Neurological 1.11 1.06 – 1.16 2.83e-05 1870 19539 exclusion phecode
345.1 Epilepsy Neurological 1.08 0.96 – 1.2 0.207 340 3384 exclusion phecode
345.11 Generalized convulsive epilepsy Neurological 1.07 0.913 – 1.26 0.388 167 1721 exclusion phecode
345.12 Partial epilepsy Neurological 1.06 0.87 – 1.29 0.561 111 1117 exclusion phecode
345.3 Convulsions Neurological 1.02 0.95 – 1.1 0.543 798 8679 exclusion phecode
346.1
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of skull and head
 Neurological 1.28 0.954 – 1.71 0.1 48 552 exclusion phecode
348 Other conditions of brain Neurological 1.14 1.01 – 1.29 0.0408 278 3018 exclusion phecode
348.2 Cerebral edema and compression of brain Neurological 1.16 0.942 – 1.43 0.163 103 1061 exclusion phecode
348.4 Cerebral cysts Neurological 1.01 0.76 – 1.33 0.97 61 511 exclusion phecode
348.7 Coma Neurological 1.03 0.86 – 1.25 0.718 127 1360 exclusion phecode
348.8 Encephalopathy, not elsewhere classified Neurological 1.23 0.977 – 1.56 0.0783 77 964 exclusion phecode
348.9 Other conditions of brain, NOS Neurological 1.01 0.846 – 1.2 0.941 128 1494 exclusion phecode
349
Other and unspecified disorders of the nervous
Other and unspecified disorders of the nervous system
 Neurological 1.2 0.99 – 1.45 0.0638 126 1335 exclusion phecode
350 Abnormal movement Neurological 1.11 1.04 – 1.19 0.00263 951 10155 exclusion phecode
350.1 Abnormal involuntary movements Neurological 1.17 1.05 – 1.31 0.00621 339 3363 exclusion phecode
350.2 Abnormality of gait Neurological 1.08 0.984 – 1.17 0.107 552 5987 exclusion phecode
350.3 Lack of coordination Neurological 1.08 0.899 – 1.31 0.398 126 1349 exclusion phecode
350.6 Disturbances of sensation of smell and taste Neurological 1.24 0.825 – 1.87 0.301 23 204 exclusion phecode
351 Other peripheral nerve disorders Neurological 1.11 1.08 – 1.15 1.8e-11 4529 50460 exclusion phecode
352 Disorders of other cranial nerves Neurological 1.08 0.982 – 1.18 0.116 515 5425 exclusion phecode
352.1 Trigeminal nerve disorders [CN5] Neurological 1.08 0.917 – 1.27 0.358 165 1900 exclusion phecode
352.2 Facial nerve disorders [CN7] Neurological 1.1 0.98 – 1.23 0.107 338 3409 exclusion phecode
353 Nerve root and plexus disorders Neurological 0.996 0.894 – 1.11 0.946 374 4298 exclusion phecode
353.1 Nerve plexus lesions Neurological 1.06 0.794 – 1.43 0.677 48 470 exclusion phecode
353.2 Nerve root lesions Neurological 0.968 0.601 – 1.56 0.895 21 212 exclusion phecode
356 Hereditary and idiopathic peripheral neuropathy Neurological 1.24 0.918 – 1.66 0.163 50 552 exclusion phecode
357 Inflammatory and toxic neuropathy Neurological 1.06 0.964 – 1.17 0.226 482 5051 exclusion phecode
358 Myoneural disorders Neurological 1.01 0.789 – 1.28 0.957 77 740 exclusion phecode
358.1 Myasthenia gravis Neurological 0.973 0.762 – 1.24 0.827 73 689 exclusion phecode
359 Muscular dystrophies and other myopathies Neurological 1.03 0.883 – 1.2 0.697 178 1815 exclusion phecode
359.1 Muscular dystrophies Neurological 1.13 0.849 – 1.5 0.402 54 493 exclusion phecode
359.2 Myopathy Neurological 1.03 0.863 – 1.24 0.723 133 1419 exclusion phecode
360 Disorders of the globe Sense Organs 1 0.833 – 1.21 0.971 125 1312 exclusion phecode
360.2 Progressive myopia Sense Organs 0.912 0.74 – 1.12 0.389 92 948 exclusion phecode
361 Retinal detachments and defects Sense Organs 0.958 0.903 – 1.02 0.16 1240 11543 exclusion phecode
361.1 Retinal detachment with retinal defect Sense Organs 0.98 0.894 – 1.07 0.675 520 4919 exclusion phecode
361.2 Retinoschisis and retinal cysts Sense Organs 0.876 0.626 – 1.23 0.441 37 273 exclusion phecode
362 Other retinal disorders Sense Organs 1.02 0.962 – 1.08 0.558 1399 14316 exclusion phecode
362.2
Degeneration of macula and posterior pole of
Degeneration of macula and posterior pole of retina
 Sense Organs 1.05 0.971 – 1.13 0.241 801 8314 exclusion phecode
362.29 Macular degeneration (senile) of retina NOS Sense Organs 1.05 0.97 – 1.13 0.242 801 8297 exclusion phecode
362.3 Other nondiabetic retinopathy Sense Organs 0.957 0.735 – 1.24 0.741 55 574 exclusion phecode
362.31 Separation of retinal layers Sense Organs 1.09 0.778 – 1.53 0.617 33 368 exclusion phecode
362.4 Retinal vascular changes and abnomalities Sense Organs 0.992 0.881 – 1.12 0.899 304 3069 exclusion phecode
362.6 Peripheral retinal degenerations Sense Organs 1.04 0.802 – 1.35 0.765 71 655 exclusion phecode
362.7 Hereditary retinal dystrophies Sense Organs 1.06 0.77 – 1.46 0.726 41 323 exclusion phecode
362.8 Retinal hemorrhage/ischemia Sense Organs 1.45 1.03 – 2.06 0.0338 38 420 exclusion phecode
363
Chorioretinal inflammations, scars, and other
Chorioretinal inflammations, scars, and other disorders of choroid
 Sense Organs 0.909 0.711 – 1.16 0.448 74 674 exclusion phecode
363.3 Chorioretinal scars Sense Organs 0.79 0.537 – 1.16 0.231 31 266 exclusion phecode
364 Corneal opacity and other disorders of cornea Sense Organs 0.896 0.787 – 1.02 0.1 255 2447 exclusion phecode
364.1 Corneal opacity Sense Organs 1 0.705 – 1.42 0.991 32 352 exclusion phecode
364.2 Corneal edema Sense Organs 0.815 0.549 – 1.21 0.311 28 290 exclusion phecode
364.4 Corneal degenerations Sense Organs 0.791 0.633 – 0.988 0.0388 89 747 exclusion phecode
364.41 Keratoconus Sense Organs 0.657 0.476 – 0.906 0.0105 45 320 exclusion phecode
364.5 Corneal dystrophy Sense Organs 1.08 0.85 – 1.38 0.519 73 820 exclusion phecode
364.9 Cornea replaced by transplant Sense Organs 0.947 0.679 – 1.32 0.748 35 406 exclusion phecode
365 Glaucoma Sense Organs 1.01 0.958 – 1.06 0.739 1655 16267 exclusion phecode
365.1 Open-angle glaucoma Sense Organs 0.919 0.825 – 1.02 0.123 383 3690 exclusion phecode
365.11 Primary open angle glaucoma Sense Organs 0.914 0.821 – 1.02 0.104 379 3678 exclusion phecode
365.2 Primary angle-closure glaucoma Sense Organs 1.16 1.02 – 1.31 0.0199 286 2776 exclusion phecode
366 Cataract Sense Organs 1.03 1 – 1.05 0.0353 7091 63159 exclusion phecode
366.1 Nonsenile Cataract Sense Organs 1.33 0.925 – 1.91 0.124 30 277 exclusion phecode
366.2 Senile cataract Sense Organs 1.05 1.01 – 1.09 0.0205 2876 31149 exclusion phecode
366.3 Traumatic cataract Sense Organs 0.959 0.692 – 1.33 0.799 34 384 exclusion phecode
367
Disorders of refraction and accommodation
Disorders of refraction and accommodation; blindness and low vision
 Sense Organs 1.01 0.94 – 1.08 0.802 889 9161 exclusion phecode
367.1 Myopia Sense Organs 0.941 0.853 – 1.04 0.222 461 4745 exclusion phecode
367.2 Astigmatism Sense Organs 0.962 0.764 – 1.21 0.746 84 737 exclusion phecode
367.8 Hypermetropia Sense Organs 1.39 1.12 – 1.73 0.00275 91 954 exclusion phecode
367.9 Blindness and low vision Sense Organs 1.06 0.925 – 1.21 0.422 256 2714 exclusion phecode
368 Visual disturbances Sense Organs 1.1 1.03 – 1.17 0.00393 1102 11462 exclusion phecode
368.1 Amblyopia Sense Organs 0.945 0.815 – 1.09 0.448 198 1945 exclusion phecode
368.2 Diplopia and disorders of binocular vision Sense Organs 1.14 0.998 – 1.29 0.054 265 2793 exclusion phecode
368.3 Anisometropia Sense Organs 0.93 0.706 – 1.22 0.603 56 554 exclusion phecode
368.4 Visual field defects Sense Organs 1.05 0.854 – 1.29 0.651 107 1266 exclusion phecode
368.9 Subjective visual disturbances Sense Organs 1.2 1.05 – 1.37 0.00899 238 2509 exclusion phecode
369 Infection of the eye Sense Organs 0.968 0.836 – 1.12 0.659 218 2150 exclusion phecode
369.2 Eye infection, viral Sense Organs 0.738 0.53 – 1.03 0.0709 47 484 exclusion phecode
369.5 Conjunctivitis, infectious Sense Organs 0.884 0.699 – 1.12 0.304 82 811 exclusion phecode
370 Keratitis Sense Organs 1.06 0.87 – 1.28 0.58 110 1157 exclusion phecode
370.1 Corneal ulcer Sense Organs 1.11 0.844 – 1.47 0.445 54 553 exclusion phecode
371 Inflammation of the eye Sense Organs 1.04 0.976 – 1.1 0.238 1181 11912 exclusion phecode
371.1 Uveitis, noninfectious or NOS Sense Organs 0.991 0.847 – 1.16 0.913 167 1880 exclusion phecode
371.3 Inflammation of eyelids Sense Organs 1.06 0.99 – 1.14 0.094 948 9181 exclusion phecode
372 Disorders of conjunctiva Sense Organs 1.13 1 – 1.29 0.0497 280 2921 exclusion phecode
374 Other disorders of eyelids Sense Organs 1.03 0.981 – 1.08 0.244 2042 21978 exclusion phecode
374.1 Ectropion or entropion Sense Organs 1.04 0.935 – 1.17 0.443 358 3802 exclusion phecode
374.3 Ptosis of eyelid Sense Organs 1.05 0.968 – 1.14 0.246 689 7044 exclusion phecode
375 Disorders of lacrimal system Sense Organs 1.07 0.999 – 1.15 0.0532 887 8748 exclusion phecode
375.2 Epiphora Sense Organs 1.09 0.978 – 1.22 0.117 354 3495 exclusion phecode
376 Disorders of the orbit Sense Organs 1.12 0.778 – 1.6 0.552 36 334 exclusion phecode
377 Disorders of optic nerve and visual pathways Sense Organs 0.948 0.8 – 1.12 0.538 152 1460 exclusion phecode
377.1 Optic atrophy Sense Organs 0.985 0.654 – 1.48 0.941 25 213 exclusion phecode
377.3 Optic neuritis/neuropathy Sense Organs 0.8 0.602 – 1.06 0.125 55 534 exclusion phecode
378
Strabismus and other disorders of binocular eye
Strabismus and other disorders of binocular eye movements
 Sense Organs 1.08 0.984 – 1.18 0.106 556 5375 exclusion phecode
378.1 Strabismus (not specified as paralytic) Sense Organs 1.08 0.972 – 1.21 0.149 364 3499 exclusion phecode
378.2 Nystagmus and other irregular eye movements Sense Organs 1.18 0.941 – 1.47 0.153 90 809 exclusion phecode
378.5 Paralytic strabismus Sense Organs 0.983 0.798 – 1.21 0.876 101 1042 exclusion phecode
379 Other disorders of eye Sense Organs 1.02 0.967 – 1.09 0.418 1298 14063 exclusion phecode
379.2 Disorders of vitreous body Sense Organs 1 0.911 – 1.1 0.998 505 5064 exclusion phecode
379.3 Aphakia and other disorders of lens Sense Organs 1.03 0.947 – 1.12 0.481 600 6877 exclusion phecode
379.4 Anomalies of pupillary function Sense Organs 1.39 0.95 – 2.04 0.0901 31 283 exclusion phecode
379.5 Disorders of iris and ciliary body Sense Organs 1.15 0.971 – 1.36 0.106 152 1533 exclusion phecode
379.9 Pain, swelling or discharge of eye Sense Organs 0.996 0.772 – 1.29 0.975 62 686 exclusion phecode
380 Disorders of external ear Sense Organs 1.12 0.972 – 1.29 0.116 211 2485 exclusion phecode
380.1 Otitis externa Sense Organs 1.07 0.912 – 1.25 0.411 172 2105 exclusion phecode
380.4 Impacted cerumen Sense Organs 0.908 0.755 – 1.09 0.304 135 1381 exclusion phecode
381 Otitis media and Eustachian tube disorders Sense Organs 1.02 0.943 – 1.1 0.673 759 8237 exclusion phecode
381.1 Otitis media Sense Organs 1.02 0.938 – 1.11 0.649 623 6719 exclusion phecode
381.11 Suppurative and unspecified otitis media Sense Organs 1.02 0.901 – 1.15 0.794 301 3285 exclusion phecode
381.2 Eustachian tube disorders Sense Organs 1.24 0.962 – 1.59 0.0971 70 785 exclusion phecode
381.3 Mastoiditis & related conditions Sense Organs 0.839 0.653 – 1.08 0.169 70 672 exclusion phecode
381.9 Otorrhea Sense Organs 1.01 0.81 – 1.26 0.925 83 1088 exclusion phecode
382 Otalgia Sense Organs 0.943 0.779 – 1.14 0.547 122 1199 exclusion phecode
383 Otosclerosis Sense Organs 0.943 0.782 – 1.14 0.535 127 1244 exclusion phecode
384 Other disorders of tympanic membrane Sense Organs 1.16 1.05 – 1.28 0.003 450 5009 exclusion phecode
384.4 Perforation of tympanic membrane Sense Organs 1.16 1.04 – 1.29 0.00679 367 3990 exclusion phecode
385 Other disorders of middle ear and mastoid Sense Organs 0.95 0.839 – 1.08 0.417 270 2943 exclusion phecode
385.3 Cholesteatoma Sense Organs 0.901 0.781 – 1.04 0.148 207 2223 exclusion phecode
385.5
Tympanosclerosis and middle ear disease related
Tympanosclerosis and middle ear disease related to otitis media
 Sense Organs 1.15 0.929 – 1.43 0.196 92 943 exclusion phecode
386
Vertiginous syndromes and other disorders of
Vertiginous syndromes and other disorders of vestibular system
 Sense Organs 1.09 1.01 – 1.18 0.0328 714 6740 exclusion phecode
386.1 Meniere's disease Sense Organs 1.06 0.926 – 1.22 0.383 239 2248 exclusion phecode
386.2 Peripheral or central vertigo Sense Organs 1.16 0.979 – 1.37 0.0869 156 1392 exclusion phecode
386.3 Labyrinthitis Sense Organs 1.12 0.994 – 1.25 0.0624 329 3014 exclusion phecode
386.9
Dizziness and giddiness (Light-headedness and
Dizziness and giddiness (Light-headedness and vertigo)
 Sense Organs 1.1 1.04 – 1.15 0.000244 1754 17576 exclusion phecode
388 Other disorders of ear Sense Organs 0.966 0.765 – 1.22 0.774 78 773 exclusion phecode
389 Hearing loss Sense Organs 1.05 0.999 – 1.11 0.0562 1483 15685 exclusion phecode
389.1 Sensorineural hearing loss Sense Organs 1.14 0.971 – 1.33 0.111 166 1729 exclusion phecode
389.2 Conductive hearing loss Sense Organs 1.13 0.964 – 1.33 0.13 168 1784 exclusion phecode
389.4 Tinnitus Sense Organs 1.02 0.879 – 1.19 0.774 193 1905 exclusion phecode
394 Rheumatic disease of the heart valves Circulatory System 1.11 1.06 – 1.17 3.25e-05 1636 17815 exclusion phecode
394.2 Mitral valve disease Circulatory System 1.12 1.05 – 1.19 0.000817 1030 10947 exclusion phecode
394.3 Aortic valve disease Circulatory System 1.05 0.949 – 1.16 0.339 412 4574 exclusion phecode
394.7 Disease of tricuspid valve Circulatory System 1.17 1.05 – 1.31 0.00511 358 3824 exclusion phecode
395 Heart valve disorders Circulatory System 1.11 1.05 – 1.18 0.000127 1406 15276 exclusion phecode
395.1 Nonrheumatic mitral valve disorders Circulatory System 1.12 1.05 – 1.19 0.00104 991 10561 exclusion phecode
395.2 Nonrheumatic aortic valve disorders Circulatory System 1.3 1.04 – 1.63 0.0204 82 972 exclusion phecode
395.3 Nonrheumatic tricuspid valve disorders Circulatory System 1.11 0.811 – 1.52 0.518 41 394 exclusion phecode
395.4 Nonrheumatic pulmonary valve disorders Circulatory System 1.57 1.09 – 2.27 0.016 32 348 exclusion phecode
395.6 Heart valve replaced Circulatory System 1.03 0.941 – 1.14 0.492 476 5286 exclusion phecode
396 Abnormal heart sounds Circulatory System 1.11 1.01 – 1.23 0.0335 440 4312 exclusion phecode
401 Hypertension Circulatory System 1.09 1.07 – 1.1 8e-31 25518 107621 exclusion phecode
401.1 Essential hypertension Circulatory System 1.09 1.07 – 1.1 1.33e-30 25453 107522 exclusion phecode
401.2 Hypertensive heart and/or renal disease Circulatory System 1.11 1.02 – 1.21 0.013 570 7090 exclusion phecode
401.21 Hypertensive heart disease Circulatory System 1.21 0.986 – 1.47 0.0681 96 1359 exclusion phecode
401.22 Hypertensive chronic kidney disease Circulatory System 1.09 0.994 – 1.2 0.0679 477 5802 exclusion phecode
401.3 Other hypertensive complications Circulatory System 1.39 0.984 – 1.96 0.0615 35 553 exclusion phecode
402
Elevated blood pressure reading without
Elevated blood pressure reading without diagnosis of hypertension
 Circulatory System 1.09 0.996 – 1.19 0.0604 552 5712 exclusion phecode
411 Ischemic Heart Disease Circulatory System 1.08 1.06 – 1.1 7.23e-12 9188 80944 exclusion phecode
411.1 Unstable angina (intermediate coronary syndrome) Circulatory System 1.12 1.06 – 1.18 8.83e-05 1439 19093 exclusion phecode
411.2 Myocardial infarction Circulatory System 1.11 1.07 – 1.15 1.28e-07 3094 40443 exclusion phecode
411.3 Angina pectoris Circulatory System 1.1 1.07 – 1.14 3.92e-10 4586 53391 exclusion phecode
411.4 Coronary atherosclerosis Circulatory System 1.07 1.04 – 1.1 9.91e-06 5639 57091 exclusion phecode
411.41 Aneurysm and dissection of heart Circulatory System 1.1 0.972 – 1.25 0.13 271 2640 exclusion phecode
411.8
Other chronic ischemic heart disease
Other chronic ischemic heart disease, unspecified
 Circulatory System 1.09 1.06 – 1.13 5.42e-08 4088 48138 exclusion phecode
411.9
Other acute and subacute forms of ischemic
Other acute and subacute forms of ischemic heart disease
 Circulatory System 1.03 0.925 – 1.15 0.564 341 4450 exclusion phecode
414 Other forms of chronic heart disease Circulatory System 1.09 0.996 – 1.2 0.0606 500 6547 exclusion phecode
414.2 ASCVD Circulatory System 1.6 0.931 – 2.75 0.089 12 267 exclusion phecode
415 Pulmonary heart disease Circulatory System 1.09 1.03 – 1.14 0.00181 1600 16666 exclusion phecode
415.11 Pulmonary embolism and infarction, acute Circulatory System 0.606 0.414 – 0.887 0.00994 29 290 exclusion phecode
415.2 Chronic pulmonary heart disease Circulatory System 0.964 0.826 – 1.13 0.646 177 2189 exclusion phecode
415.21 Primary pulmonary hypertension Circulatory System 1.03 0.869 – 1.23 0.713 139 1655 exclusion phecode
416 Cardiomegaly Circulatory System 1.07 0.994 – 1.14 0.073 870 9548 exclusion phecode
418 Nonspecific chest pain Circulatory System 1.09 1.07 – 1.11 1.32e-16 10113 105402 exclusion phecode
418.1 Precordial pain Circulatory System 1.11 1.05 – 1.18 0.000345 1305 13885 exclusion phecode
420 Carditis Circulatory System 0.975 0.901 – 1.05 0.521 704 7743 exclusion phecode
420.1 Myocarditis Circulatory System 1.26 0.896 – 1.78 0.183 37 461 exclusion phecode
420.2 Pericarditis Circulatory System 0.964 0.871 – 1.07 0.484 421 4832 exclusion phecode
420.21 Acute pericarditis Circulatory System 0.992 0.779 – 1.26 0.951 69 832 exclusion phecode
420.22 Chronic pericarditis Circulatory System 1.21 0.865 – 1.68 0.269 37 427 exclusion phecode
420.3 Endocarditis Circulatory System 0.983 0.866 – 1.12 0.797 266 2703 exclusion phecode
425 Cardiomyopathy Circulatory System 1.09 0.985 – 1.2 0.0965 454 4582 exclusion phecode
425.1 Primary/intrinsic cardiomyopathies Circulatory System 1.1 0.999 – 1.22 0.0518 447 4465 exclusion phecode
425.11 Hypertrophic obstructive cardiomyopathy Circulatory System 1.02 0.769 – 1.35 0.902 56 504 exclusion phecode
425.12 Other hypertrophic cardiomyopathy Circulatory System 1.05 0.792 – 1.38 0.749 59 626 exclusion phecode
425.8 Other cardiomyopathy Circulatory System 0.763 0.436 – 1.34 0.344 15 186 exclusion phecode
426 Cardiac conduction disorders Circulatory System 1.07 1.02 – 1.12 0.0024 2239 24828 exclusion phecode
426.2 Atrioventricular [AV] block Circulatory System 1.11 1.02 – 1.2 0.0154 664 7420 exclusion phecode
426.21 First degree AV block Circulatory System 1.14 1.01 – 1.28 0.0328 320 3427 exclusion phecode
426.23 Second degree AV block Circulatory System 1.02 0.861 – 1.21 0.806 148 1550 exclusion phecode
426.24 Atrioventricular block, complete Circulatory System 1.05 0.901 – 1.24 0.507 170 2039 exclusion phecode
426.25 Other heart block Circulatory System 1.21 0.87 – 1.69 0.256 41 453 exclusion phecode
426.3 Bundle branch block Circulatory System 1.03 0.965 – 1.09 0.392 1083 12204 exclusion phecode
426.31 Right bundle branch block Circulatory System 1.02 0.933 – 1.12 0.613 488 5383 exclusion phecode
426.32 Left bundle branch block Circulatory System 1.05 0.964 – 1.15 0.26 564 6503 exclusion phecode
426.4 Anomalous atrioventricular excitation Circulatory System 1.2 0.947 – 1.52 0.131 80 928 exclusion phecode
426.8 Other cardiac conduction disorders Circulatory System 1.38 0.857 – 2.23 0.185 19 244 exclusion phecode
426.9 Cardiac pacemaker/device in situ Circulatory System 1.11 1.03 – 1.19 0.00776 792 8687 exclusion phecode
426.91 Cardiac pacemaker in situ Circulatory System 1.11 1.03 – 1.2 0.00928 740 7958 exclusion phecode
427 Cardiac dysrhythmias Circulatory System 1.06 1.04 – 1.09 3.96e-07 8219 78159 exclusion phecode
427.1 Paroxysmal tachycardia, unspecified Circulatory System 1.07 1 – 1.14 0.0349 1095 12052 exclusion phecode
427.11 Paroxysmal supraventricular tachycardia Circulatory System 1.05 0.975 – 1.13 0.203 832 8998 exclusion phecode
427.12 Paroxysmal ventricular tachycardia Circulatory System 1.06 0.943 – 1.2 0.315 284 3357 exclusion phecode
427.2 Atrial fibrillation and flutter Circulatory System 1.06 1.03 – 1.09 0.00014 4745 48108 exclusion phecode
427.3 Other specified cardiac dysrhythmias Circulatory System 1.07 1 – 1.13 0.0403 1129 11549 exclusion phecode
427.4 Cardiac arrest and ventricular fibrillation Circulatory System 1.01 0.903 – 1.14 0.831 318 4245 exclusion phecode
427.41 Ventricular fibrillation and flutter Circulatory System 0.799 0.652 – 0.979 0.0307 98 1221 exclusion phecode
427.42 Cardiac arrest Circulatory System 1.08 0.955 – 1.23 0.21 260 3530 exclusion phecode
427.5 Arrhythmia (cardiac) NOS Circulatory System 1.06 0.94 – 1.2 0.343 303 3609 exclusion phecode
427.6 Premature beats Circulatory System 1.03 0.888 – 1.2 0.682 189 2035 exclusion phecode
427.61 Supraventricular premature beats Circulatory System 1.04 0.779 – 1.39 0.797 50 443 exclusion phecode
427.7 Tachycardia NOS Circulatory System 1.06 0.981 – 1.14 0.144 731 8596 exclusion phecode
427.8 Sinoatrial node dysfunction (Bradycardia) Circulatory System 1.09 0.929 – 1.28 0.285 163 1407 exclusion phecode
427.9 Palpitations Circulatory System 1.09 1.03 – 1.15 0.00242 1525 15377 exclusion phecode
428 Congestive heart failure; nonhypertensive Circulatory System 1.07 1.02 – 1.13 0.00967 1543 20061 exclusion phecode
428.1 Congestive heart failure (CHF) NOS Circulatory System 1.06 0.966 – 1.15 0.232 539 7651 exclusion phecode
428.2 Heart failure NOS Circulatory System 1.08 1.02 – 1.14 0.0122 1227 15827 exclusion phecode
429
Ill-defined descriptions and complications of
Ill-defined descriptions and complications of heart disease
 Circulatory System 1.02 0.897 – 1.16 0.742 253 2690 exclusion phecode
429.1 Heart transplant/surgery Circulatory System 1.04 0.622 – 1.73 0.887 13 231 exclusion phecode
429.2 Abnormal function study of cardiovascular system Circulatory System 0.998 0.856 – 1.16 0.982 181 1921 exclusion phecode
429.3 Symptoms involving cardiovascular system Circulatory System 1.1 0.864 – 1.4 0.445 72 783 exclusion phecode
430 Intracranial hemorrhage Circulatory System 1.03 0.946 – 1.12 0.508 609 7151 exclusion phecode
430.1 Subarachnoid hemorrhage Circulatory System 0.947 0.829 – 1.08 0.426 244 3341 exclusion phecode
430.2 Intracerebral hemorrhage Circulatory System 1.11 0.977 – 1.26 0.11 259 2838 exclusion phecode
430.3 Subdural hemorrhage Circulatory System 0.912 0.738 – 1.13 0.394 103 934 exclusion phecode
433 Cerebrovascular disease Circulatory System 1.09 1.04 – 1.13 4.94e-05 2703 32008 exclusion phecode
433.1 Occlusion and stenosis of precerebral arteries Circulatory System 1.2 1.06 – 1.36 0.00528 256 4162 exclusion phecode
433.12 Cerebral atherosclerosis Circulatory System 1.16 0.912 – 1.48 0.226 78 813 exclusion phecode
433.2 Occlusion of cerebral arteries Circulatory System 1.05 0.991 – 1.11 0.0971 1303 15396 exclusion phecode
433.21
Cerebral artery occlusion, with cerebral
Cerebral artery occlusion, with cerebral infarction
 Circulatory System 1.02 0.929 – 1.11 0.704 512 6058 exclusion phecode
433.3 Cerebral ischemia Circulatory System 1.06 0.992 – 1.14 0.082 888 10645 exclusion phecode
433.31 Transient cerebral ischemia Circulatory System 1.07 0.991 – 1.16 0.0828 657 7775 exclusion phecode
433.5 Cerebral aneurysm Circulatory System 1.04 0.854 – 1.26 0.722 108 1628 exclusion phecode
433.8 Late effects of cerebrovascular disease Circulatory System 1.1 0.99 – 1.22 0.0767 396 4796 exclusion phecode
440 Atherosclerosis Circulatory System 1.04 0.895 – 1.2 0.642 193 4936 exclusion phecode
440.1 Atherosclerosis of renal artery Circulatory System 0.833 0.528 – 1.31 0.43 20 434 exclusion phecode
440.2 Atherosclerosis of the extremities Circulatory System 1.16 0.929 – 1.45 0.187 79 2850 exclusion phecode
440.9 Atherosclerosis of aorta Circulatory System 1.04 0.769 – 1.4 0.813 46 1110 exclusion phecode
441 Vascular insufficiency of intestine Circulatory System 1.08 0.935 – 1.26 0.284 194 2433 exclusion phecode
441.1 Acute vascular insufficiency of intestine Circulatory System 0.987 0.798 – 1.22 0.902 95 1136 exclusion phecode
442 Other aneurysm Circulatory System 1.01 0.915 – 1.12 0.802 396 6566 exclusion phecode
442.1 Aortic aneurysm Circulatory System 0.964 0.852 – 1.09 0.567 256 5020 exclusion phecode
442.11 Abdominal aortic aneurysm Circulatory System 1.12 0.917 – 1.36 0.273 98 3144 exclusion phecode
442.2 Aneurysm of iliac artery Circulatory System 1.12 0.712 – 1.76 0.629 20 318 exclusion phecode
442.3 Aneurysm of artery of lower extremity Circulatory System 1.21 0.876 – 1.67 0.247 41 615 exclusion phecode
442.4 Arterial dissection Circulatory System 1.1 0.722 – 1.69 0.649 22 217 exclusion phecode
442.8 Aneurysm of other specified artery Circulatory System 0.927 0.725 – 1.19 0.545 69 736 exclusion phecode
443 Peripheral vascular disease Circulatory System 1.09 1.01 – 1.17 0.02 842 14759 exclusion phecode
443.1 Raynaud's syndrome Circulatory System 1.09 0.984 – 1.21 0.0978 396 4663 exclusion phecode
443.7
Peripheral angiopathy in diseases classified
Peripheral angiopathy in diseases classified elsewhere
 Circulatory System 1.09 0.897 – 1.33 0.377 106 1424 exclusion phecode
443.8 Other specified peripheral vascular diseases Circulatory System 1.1 1.02 – 1.18 0.0138 764 13866 exclusion phecode
443.9 Peripheral vascular disease, unspecified Circulatory System 1.11 0.998 – 1.23 0.0543 379 9380 exclusion phecode
444 Arterial embolism and thrombosis Circulatory System 1.1 0.927 – 1.31 0.269 136 3394 exclusion phecode
444.1
Arterial embolism and thrombosis of lower
Arterial embolism and thrombosis of lower extremity artery
 Circulatory System 1.11 0.872 – 1.42 0.392 67 1958 exclusion phecode
446 Polyarteritis nodosa and allied conditions Circulatory System 1 0.89 – 1.13 0.978 315 3206 exclusion phecode
446.4 Wegener's granulomatosis Circulatory System 1.12 0.885 – 1.43 0.338 76 689 exclusion phecode
446.5 Giant cell arteritis Circulatory System 0.95 0.801 – 1.13 0.555 150 1582 exclusion phecode
446.9 Arteritis NOS Circulatory System 0.839 0.671 – 1.05 0.123 91 873 exclusion phecode
447 Other disorders of arteries and arterioles Circulatory System 1.1 0.951 – 1.27 0.201 205 4897 exclusion phecode
447.1 Stricture of artery Circulatory System 1.03 0.815 – 1.29 0.819 75 3085 exclusion phecode
448 Disease of capillaries Circulatory System 1.23 0.891 – 1.7 0.208 40 541 exclusion phecode
450 Noninfectious disorders of lymphatic channels Circulatory System 1.1 0.966 – 1.25 0.148 271 2786 exclusion phecode
451 Phlebitis and thrombophlebitis Circulatory System 1.07 1.02 – 1.13 0.0119 1478 14774 exclusion phecode
451.2
Phlebitis and thrombophlebitis of lower
Phlebitis and thrombophlebitis of lower extremities
 Circulatory System 1.07 1.01 – 1.13 0.017 1392 13741 exclusion phecode
452 Other venous embolism and thrombosis Circulatory System 1.04 0.9 – 1.21 0.571 193 2206 exclusion phecode
454 Varicose veins Circulatory System 1.07 1.03 – 1.1 5.79e-05 4319 44774 exclusion phecode
454.1 Varicose veins of lower extremity Circulatory System 1.07 1.04 – 1.11 1.65e-05 4467 46144 exclusion phecode
454.11 Varicose veins of lower extremity, symptomtic Circulatory System 1.05 0.906 – 1.21 0.529 204 2506 exclusion phecode
455 Hemorrhoids Circulatory System 1.04 1.02 – 1.07 0.000156 8636 91147 exclusion phecode
456 Chronic venous insufficiency [CVI] Circulatory System 1.02 0.786 – 1.33 0.862 61 634 exclusion phecode
457
Encounter for long-term (current) use of
Encounter for long-term (current) use of anticoagulants, antithrombotics, aspirin
 Circulatory System 0.919 0.67 – 1.26 0.599 37 354 exclusion phecode
458 Hypotension Circulatory System 1.07 1.02 – 1.12 0.00765 2004 21625 exclusion phecode
458.1 Orthostatic hypotension Circulatory System 1.03 0.935 – 1.14 0.549 470 4828 exclusion phecode
458.2 Iatrogenic hypotension Circulatory System 1.17 0.924 – 1.49 0.189 77 887 exclusion phecode
458.9 Hypotension NOS Circulatory System 1.08 1.01 – 1.14 0.016 1194 13205 exclusion phecode
459 Other disorders of circulatory system Circulatory System 1.08 1.05 – 1.12 2.51e-08 5313 60709 exclusion phecode
459.1 Hemorrhage NOS Circulatory System 1.06 0.792 – 1.43 0.677 52 519 exclusion phecode
459.9 Circulatory disease NEC Circulatory System 1.09 1.06 – 1.12 1.1e-08 5265 60137 exclusion phecode
464 Acute sinusitis Respiratory 1.37 1.06 – 1.77 0.0158 66 782 exclusion phecode
465
Acute upper respiratory infections of multiple
Acute upper respiratory infections of multiple or unspecified sites
 Respiratory 1.04 0.968 – 1.12 0.278 835 8951 exclusion phecode
465.2 Acute pharyngitis Respiratory 1.04 0.922 – 1.17 0.546 312 3235 exclusion phecode
465.4 Acute laryngitis and tracheitis Respiratory 0.815 0.625 – 1.06 0.132 60 621 exclusion phecode
470 Septal Deviations/Turbinate Hypertrophy Respiratory 1.07 1.02 – 1.13 0.00662 1669 18150 exclusion phecode
471 Nasal polyps Respiratory 1.08 1.02 – 1.15 0.0136 1179 12255 exclusion phecode
472 Chronic pharyngitis and nasopharyngitis Respiratory 1.09 0.983 – 1.21 0.102 393 3663 exclusion phecode
473 Diseases of the larynx and vocal cords Respiratory 1.13 1.04 – 1.22 0.00224 718 9891 exclusion phecode
473.1 Chronic laryngitis Respiratory 1.35 0.939 – 1.95 0.105 33 410 exclusion phecode
473.3 Paralysis/spasm of vocal cords or larynx Respiratory 0.933 0.754 – 1.15 0.521 93 991 exclusion phecode
473.4 Voice disturbance Respiratory 1.12 0.994 – 1.26 0.062 305 4151 exclusion phecode
474 Acute and chronic tonsillitis Respiratory 1.05 0.964 – 1.14 0.273 640 7194 exclusion phecode
474.1 Acute tonsillitis Respiratory 1.1 0.947 – 1.27 0.221 211 2235 exclusion phecode
474.2 Chronic tonsillitis and adenoiditis Respiratory 1.02 0.921 – 1.13 0.699 411 4577 exclusion phecode
475 Chronic sinusitis Respiratory 1.1 1.03 – 1.18 0.00508 977 10071 exclusion phecode
476 Allergic rhinitis Respiratory 1.03 0.931 – 1.14 0.583 440 4181 exclusion phecode
477 Epistaxis or throat hemorrhage Respiratory 0.972 0.906 – 1.04 0.427 870 9128 exclusion phecode
478 Throat pain Respiratory 1.03 0.861 – 1.23 0.763 130 1520 exclusion phecode
479 Other upper respiratory disease Respiratory 1.1 1.04 – 1.16 0.000461 1468 15956 exclusion phecode
480 Pneumonia Respiratory 1.03 0.995 – 1.07 0.0849 2916 38931 exclusion phecode
480.1 Bacterial pneumonia Respiratory 1.01 0.965 – 1.06 0.638 1880 25119 exclusion phecode
480.11 Pneumococcal pneumonia Respiratory 1.01 0.956 – 1.06 0.805 1639 22276 exclusion phecode
480.12 Pseudomonal pneumonia Respiratory 0.908 0.584 – 1.41 0.67 24 342 exclusion phecode
480.2 Viral pneumonia Respiratory 0.827 0.56 – 1.22 0.339 27 277 exclusion phecode
480.3 Pneumonia due to fungus (mycoses) Respiratory 0.918 0.618 – 1.36 0.672 26 380 exclusion phecode
480.5 Bronchopneumonia and lung abscess Respiratory 1.01 0.883 – 1.16 0.853 222 2965 exclusion phecode
481 Influenza Respiratory 1.05 0.865 – 1.27 0.627 114 1322 exclusion phecode
483 Acute bronchitis and bronchiolitis Respiratory 1.17 0.905 – 1.52 0.231 56 754 exclusion phecode
495 Asthma Respiratory 1.1 1.07 – 1.12 1.72e-17 9620 101869 exclusion phecode
495.2 Asthma with exacerbation Respiratory 1.2 0.963 – 1.5 0.104 82 1039 exclusion phecode
496 Chronic airway obstruction Respiratory 1.12 1.06 – 1.18 1.15e-05 1627 39784 exclusion phecode
496.1 Emphysema Respiratory 1.02 0.856 – 1.21 0.835 129 6691 exclusion phecode
496.2 Chronic bronchitis Respiratory 1.1 0.967 – 1.25 0.147 249 11507 exclusion phecode
496.21 Obstructive chronic bronchitis Respiratory 1.07 0.927 – 1.24 0.34 183 10607 exclusion phecode
496.3 Bronchiectasis Respiratory 1.14 1.05 – 1.23 0.00148 706 7503 exclusion phecode
497 Bronchitis Respiratory 1.06 0.914 – 1.23 0.441 188 2525 exclusion phecode
500 Lung disease due to external agents Respiratory 1.44 1.13 – 1.83 0.00301 76 1435 exclusion phecode
500.1 Extrinsic allergic alveolitis Respiratory 1.51 1.04 – 2.19 0.0288 33 298 exclusion phecode
500.2 Pneumoconiosis Respiratory 1.18 0.817 – 1.7 0.383 33 767 exclusion phecode
501 Pneumonitis due to inhalation of food or vomitus Respiratory 1 0.864 – 1.17 0.954 186 2427 exclusion phecode
502 Postinflammatory pulmonary fibrosis Respiratory 1.06 0.926 – 1.22 0.393 223 3446 exclusion phecode
503 Pulmonary congestion and hypostasis Respiratory 1.22 1.02 – 1.46 0.0272 131 1964 exclusion phecode
504 Other alveolar and parietoalveolar pneumonopathy Respiratory 1.21 0.977 – 1.51 0.0798 91 1247 exclusion phecode
505 Other pulmonary inflamation or edema Respiratory 1.44 0.891 – 2.34 0.136 23 220 exclusion phecode
506 Empyema and pneumothorax Respiratory 0.978 0.864 – 1.11 0.726 274 4212 exclusion phecode
507 Pleurisy; pleural effusion Respiratory 1.02 0.977 – 1.07 0.319 2001 23829 exclusion phecode
508
Pulmonary collapse; interstitial and
Pulmonary collapse; interstitial and compensatory emphysema
 Respiratory 1.13 1.04 – 1.23 0.00362 616 7601 exclusion phecode
509 Respiratory failure, insufficiency, arrest Respiratory 0.979 0.9 – 1.06 0.614 593 9659 exclusion phecode
509.1 Respiratory failure Respiratory 1 0.907 – 1.1 0.999 438 7624 exclusion phecode
509.2 Respiratory insufficiency Respiratory 0.984 0.887 – 1.09 0.761 388 6742 exclusion phecode
509.5 Respiratory arrest Respiratory 0.959 0.734 – 1.25 0.762 51 557 exclusion phecode
509.8
Dependence on respirator [Ventilator] or
Dependence on respirator [Ventilator] or supplemental oxygen
 Respiratory 0.948 0.772 – 1.16 0.611 97 1491 exclusion phecode
510 Other diseases of lung Respiratory 1.05 0.897 – 1.23 0.55 168 2879 exclusion phecode
512 Other symptoms of respiratory system Respiratory 1.08 1.04 – 1.13 2.33e-05 3109 34933 exclusion phecode
512.1 Wheezing Respiratory 1.11 0.875 – 1.41 0.391 81 839 exclusion phecode
512.2 Painful respiration Respiratory 0.906 0.703 – 1.17 0.447 63 860 exclusion phecode
512.7 Shortness of breath Respiratory 1.11 1.05 – 1.16 3.23e-05 1953 22539 exclusion phecode
512.8 Cough Respiratory 1.04 0.977 – 1.11 0.21 1018 11121 exclusion phecode
512.9 Other dyspnea Respiratory 1.13 1.01 – 1.27 0.0298 323 3506 exclusion phecode
513 Respiratory abnormalities Respiratory 1.09 0.943 – 1.26 0.242 201 2282 exclusion phecode
513.3 Hypoventilation Respiratory 1.07 0.735 – 1.57 0.712 26 310 exclusion phecode
513.4 Hyperventilation Respiratory 1.1 0.895 – 1.35 0.365 102 1105 exclusion phecode
513.8 Disorders of diaphragm Respiratory 1.12 0.835 – 1.51 0.447 47 511 exclusion phecode
514 Abnormal findings examination of lungs Respiratory 1.09 0.998 – 1.19 0.0542 536 9167 exclusion phecode
516 Abnormal sputum Respiratory 1.11 1.02 – 1.22 0.0201 511 8004 exclusion phecode
516.1 Hemoptysis Respiratory 1.13 1.03 – 1.24 0.0104 503 7778 exclusion phecode
519
Other diseases of respiratory system, not
Other diseases of respiratory system, not elsewhere classified
 Respiratory 1.07 1.03 – 1.11 0.000916 2958 35949 exclusion phecode
519.2 Respiratory complications Respiratory 1.12 0.87 – 1.44 0.38 67 1239 exclusion phecode
519.8 Other diseases of respiratory system, NEC Respiratory 1.07 1.03 – 1.11 0.000499 2797 33997 exclusion phecode
519.9
Symptoms involving respiratory system and other
Symptoms involving respiratory system and other chest symptoms
 Respiratory 0.888 0.742 – 1.06 0.198 130 1240 exclusion phecode
520 Disorders of tooth development Digestive 1.01 0.936 – 1.08 0.853 836 8253 exclusion phecode
520.1 Hereditary disturbances in tooth structure Digestive 0.834 0.509 – 1.37 0.47 15 218 exclusion phecode
520.2 Disturbances in tooth eruption Digestive 0.987 0.923 – 1.06 0.7 995 9619 exclusion phecode
521 Diseases of hard tissues of teeth Digestive 1.03 0.966 – 1.1 0.372 1079 12026 exclusion phecode
521.1 Dental caries Digestive 1.03 0.969 – 1.1 0.321 1071 12064 exclusion phecode
522 Diseases of pulp and periapical tissues Digestive 1.06 0.974 – 1.15 0.173 615 7109 exclusion phecode
522.5 Periapical abscess Digestive 1.05 0.947 – 1.16 0.351 414 4722 exclusion phecode
523 Gingival and periodontal diseases Digestive 1.07 0.98 – 1.16 0.135 619 6831 exclusion phecode
523.1 Gingivitis Digestive 1.1 0.794 – 1.53 0.556 42 421 exclusion phecode
523.3 Periodontitis (acute or chronic) Digestive 1.02 0.925 – 1.13 0.667 436 4813 exclusion phecode
523.31 Acute periodontitis Digestive 1.07 0.938 – 1.22 0.31 243 2765 exclusion phecode
523.32 Chronic periodontitis Digestive 0.903 0.781 – 1.05 0.172 212 2262 exclusion phecode
524 Dentofacial anomalies, including malocclusion Digestive 0.972 0.811 – 1.16 0.753 137 1333 exclusion phecode
524.3 Anomalies of tooth position/malocclusion Digestive 1 0.832 – 1.21 0.969 130 1206 exclusion phecode
525
Other diseases of the teeth and supporting
Other diseases of the teeth and supporting structures
 Digestive 1.07 1 – 1.15 0.0413 981 10567 exclusion phecode
525.2 Atrophy of edentulous alveolar ridge Digestive 1.25 0.849 – 1.83 0.261 27 263 exclusion phecode
526 Diseases of the jaws Digestive 1.01 0.904 – 1.13 0.83 325 3737 exclusion phecode
526.1 Cysts of the jaws Digestive 1.09 0.887 – 1.33 0.421 102 1245 exclusion phecode
526.3 Anomalies of jaw size/symmetry Digestive 1.02 0.688 – 1.51 0.921 26 243 exclusion phecode
526.4 Temporomandibular joint disorders Digestive 1.14 0.931 – 1.4 0.204 97 1012 exclusion phecode
526.41 Temporomandibular joint disorder, unspecified Digestive 1.14 0.925 – 1.4 0.222 94 994 exclusion phecode
526.5 Inflammatory conditions of jaw Digestive 0.951 0.664 – 1.36 0.786 31 429 exclusion phecode
526.9 Jaw disease NOS Digestive 0.873 0.695 – 1.1 0.241 84 976 exclusion phecode
527 Diseases of the salivary glands Digestive 1.24 1.08 – 1.43 0.00278 226 2813 exclusion phecode
527.1 Hypertrophy of salivary gland Digestive 1.22 0.852 – 1.74 0.28 32 352 exclusion phecode
527.2 Sialoadenitis Digestive 1.21 0.991 – 1.48 0.0608 108 1472 exclusion phecode
527.7 Disturbance of salivary secretion Digestive 1.69 1.06 – 2.67 0.0259 21 234 exclusion phecode
527.8 Other specified diseases of the salivary glands Digestive 1.34 0.942 – 1.9 0.104 36 467 exclusion phecode
528
Diseases of the oral soft tissues, excluding
Diseases of the oral soft tissues, excluding lesions specific for gingiva and tongue
 Digestive 1.06 1 – 1.12 0.0389 1334 15394 exclusion phecode
528.1 Stomatitis and mucositis Digestive 0.976 0.841 – 1.13 0.748 191 1809 exclusion phecode
528.11 Stomatitis and mucositis (ulcerative) Digestive 1.02 0.86 – 1.2 0.86 159 1493 exclusion phecode
528.12 Oral aphthae Digestive 0.815 0.58 – 1.14 0.238 33 345 exclusion phecode
528.3 Cellulitis and abscess of oral soft tissues Digestive 1.21 0.915 – 1.61 0.178 50 743 exclusion phecode
528.4 Cysts of oral soft tissues Digestive 1.21 0.869 – 1.68 0.261 42 509 exclusion phecode
528.41 Cyst of the salivary gland Digestive 1.17 0.818 – 1.66 0.394 35 387 exclusion phecode
528.5 Diseases of lips Digestive 0.98 0.86 – 1.12 0.763 248 2706 exclusion phecode
528.6 Leukoplakia of oral mucosa Digestive 1.02 0.826 – 1.26 0.855 91 1196 exclusion phecode
528.7 Sialolithiasis Digestive 1.04 0.847 – 1.29 0.682 95 1263 exclusion phecode
529 Diseases and other conditions of the tongue Digestive 1.03 0.928 – 1.14 0.618 424 4926 exclusion phecode
529.1 Glossitis Digestive 0.974 0.79 – 1.2 0.802 100 1169 exclusion phecode
530 Diseases of esophagus Digestive 1.09 1.07 – 1.11 2.93e-18 11804 109669 exclusion phecode
530.1 Esophagitis, GERD and related diseases Digestive 1.09 1.07 – 1.11 5.43e-17 11040 106772 exclusion phecode
530.11 GERD Digestive 1.09 1.06 – 1.11 1.47e-12 8116 88546 exclusion phecode
530.12 Ulcer of esophagus Digestive 1.06 1.01 – 1.11 0.0243 1750 19410 exclusion phecode
530.14 Reflux esophagitis Digestive 1.1 1.06 – 1.14 4.01e-08 3646 40537 exclusion phecode
530.2 Esophageal bleeding (varices/hemorrhage) Digestive 1.07 0.985 – 1.17 0.106 577 6519 exclusion phecode
530.3 Stricture and stenosis of esophagus Digestive 1.06 0.979 – 1.15 0.146 635 6920 exclusion phecode
530.5 Disorders of esophageal motility Digestive 1.15 1.01 – 1.31 0.0386 245 2551 exclusion phecode
530.6 Diverticulum of esophagus, acquired Digestive 1.06 0.793 – 1.41 0.708 52 536 exclusion phecode
530.7 Gastroesophageal laceration-hemorrhage syndrome Digestive 1.1 0.91 – 1.34 0.316 113 1331 exclusion phecode
530.9 Heartburn Digestive 1.14 1.06 – 1.23 0.000416 792 8337 exclusion phecode
531 Peptic ulcer (excl. esophageal) Digestive 1.12 1.07 – 1.17 9.97e-07 2218 26758 exclusion phecode
531.1 Hemorrhage from gastrointestinal ulcer Digestive 1.19 1.02 – 1.38 0.0291 188 2327 exclusion phecode
531.2 Gastric ulcer Digestive 1.13 1.06 – 1.19 4.86e-05 1324 15663 exclusion phecode
531.3 Duodenal ulcer Digestive 1.1 1.02 – 1.17 0.00987 898 11132 exclusion phecode
531.4 Peptic ulcer, site unspecified Digestive 1.25 1.03 – 1.51 0.0271 117 1600 exclusion phecode
532 Dysphagia Digestive 1.12 1.08 – 1.17 8.39e-08 2382 25224 exclusion phecode
535 Gastritis and duodenitis Digestive 1.07 1.04 – 1.09 5.44e-09 9604 102418 exclusion phecode
535.1 Acute gastritis Digestive 0.999 0.901 – 1.11 0.985 404 4703 exclusion phecode
535.2 Atrophic gastritis Digestive 0.948 0.792 – 1.13 0.561 137 1378 exclusion phecode
535.6 Duodenitis Digestive 1.08 1.03 – 1.13 0.00061 2240 28909 exclusion phecode
535.8 Other specified gastritis Digestive 1.08 1.04 – 1.12 0.000157 2891 31775 exclusion phecode
535.9 Gastritis and duodenitis, NOS Digestive 1.27 0.908 – 1.78 0.162 37 447 exclusion phecode
536.8
Dyspepsia and other specified disorders of
Dyspepsia and other specified disorders of function of stomach
 Digestive 1.12 0.9 – 1.39 0.311 89 1020 exclusion phecode
537 Other disorders of stomach and duodenum Digestive 1.12 1.05 – 1.19 0.000319 1166 13242 exclusion phecode
540 Appendiceal conditions Digestive 1.02 0.96 – 1.08 0.514 1176 12316 exclusion phecode
540.1 Appendicitis Digestive 1.05 0.982 – 1.11 0.16 1097 11561 exclusion phecode
540.11 Acute appendicitis Digestive 1.01 0.947 – 1.08 0.747 995 10302 exclusion phecode
550 Abdominal hernia Digestive 1.06 1.04 – 1.08 4.92e-12 16103 111235 exclusion phecode
550.1 Inguinal hernia Digestive 1.04 1.01 – 1.07 0.0199 5284 42552 exclusion phecode
550.2 Diaphragmatic hernia Digestive 1.07 1.05 – 1.09 5.41e-10 9759 93168 exclusion phecode
550.3 Femoral hernia Digestive 0.902 0.782 – 1.04 0.154 221 2669 exclusion phecode
550.4 Umbilical hernia Digestive 1.09 1.02 – 1.15 0.00754 1206 13558 exclusion phecode
550.5 Ventral hernia Digestive 1.11 1.05 – 1.18 0.000771 1132 13325 exclusion phecode
555
Inflammatory bowel disease and other
Inflammatory bowel disease and other gastroenteritis and colitis
 Digestive 1.02 0.963 – 1.07 0.558 1457 17554 exclusion phecode
555.1 Regional enteritis Digestive 1 0.919 – 1.09 0.944 569 6990 exclusion phecode
555.2 Ulcerative colitis Digestive 1.01 0.95 – 1.08 0.699 1050 12422 exclusion phecode
555.21 Ulcerative colitis (chronic) Digestive 1.03 0.877 – 1.2 0.741 167 2185 exclusion phecode
556 Ulceration of the lower GI tract Digestive 1.13 1.02 – 1.27 0.026 357 4186 exclusion phecode
556.1 Ulceration of intestine Digestive 1.26 1.09 – 1.46 0.00197 218 2624 exclusion phecode
557 Intestinal malabsorption (non-celiac) Digestive 0.978 0.81 – 1.18 0.814 118 1162 exclusion phecode
557.1 Celiac disease Digestive 0.89 0.826 – 0.959 0.0022 794 7497 exclusion phecode
558 Noninfectious gastroenteritis Digestive 1.05 1.02 – 1.08 0.00159 5718 62667 exclusion phecode
559 Ileostomy status Digestive 1.05 0.963 – 1.15 0.262 549 6265 exclusion phecode
560 Intestinal obstruction without mention of hernia Digestive 0.991 0.937 – 1.05 0.741 1392 15542 exclusion phecode
560.1 Paralytic ileus Digestive 1.05 0.898 – 1.23 0.537 167 2027 exclusion phecode
560.2 Impaction of intestine Digestive 1.1 0.896 – 1.34 0.372 104 1071 exclusion phecode
560.3 Peritoneal or intestinal adhesions Digestive 0.974 0.86 – 1.1 0.681 284 3305 exclusion phecode
560.4 Other intestinal obstruction Digestive 0.985 0.928 – 1.05 0.63 1196 13343 exclusion phecode
561 Symptoms involving digestive system Digestive 1.1 1.07 – 1.13 6.78e-13 6148 64179 exclusion phecode
561.1 Diarrhea Digestive 1.17 1.01 – 1.37 0.0406 176 1880 exclusion phecode
561.2 Flatulence Digestive 1.03 0.951 – 1.12 0.461 669 6826 exclusion phecode
562 Diverticulosis and diverticulitis Digestive 1.06 1.04 – 1.08 3.88e-07 9034 82424 exclusion phecode
562.1 Diverticulosis Digestive 1.06 1.04 – 1.08 4.46e-07 9023 82402 exclusion phecode
563 Constipation Digestive 1.07 1.03 – 1.1 0.000179 3726 41364 exclusion phecode
564 Functional digestive disorders Digestive 1.08 1.06 – 1.11 1.22e-10 7615 82801 exclusion phecode
564.1 Irritable Bowel Syndrome Digestive 1.1 1.05 – 1.15 2.21e-05 2209 23067 exclusion phecode
564.8
Abnormal findings on exam of gastrointestinal
Abnormal findings on exam of gastrointestinal tract/ abdominal area
 Digestive 1.09 1.01 – 1.19 0.0371 604 6584 exclusion phecode
564.9 Personal history of diseases of digestive system Digestive 1.08 1.05 – 1.11 4.47e-07 5038 58491 exclusion phecode
565 Anal and rectal conditions Digestive 1.05 1.02 – 1.08 0.00232 4653 56709 exclusion phecode
565.1 Anal and rectal polyp Digestive 1.03 0.988 – 1.08 0.155 2060 27593 exclusion phecode
567 Peritonitis and retroperitoneal infections Digestive 1.04 0.921 – 1.18 0.525 290 3516 exclusion phecode
568 Other disorders of peritoneum Digestive 1.07 1.01 – 1.14 0.0278 1191 13219 exclusion phecode
568.1
Peritoneal adhesions (postoperative)
Peritoneal adhesions (postoperative) (postinfection)
 Digestive 1.07 1.01 – 1.14 0.0306 1134 12548 exclusion phecode
569 Other disorders of intestine Digestive 1.02 0.966 – 1.08 0.466 1437 16346 exclusion phecode
569.1 Toxic gastroenteritis and colitis Digestive 1.29 0.995 – 1.67 0.0547 64 560 exclusion phecode
569.2 Gastrointestinal complications Digestive 0.936 0.795 – 1.1 0.433 156 1893 exclusion phecode
571 Chronic liver disease and cirrhosis Digestive 1.07 0.998 – 1.14 0.0554 949 11451 exclusion phecode
571.5 Other chronic nonalcoholic liver disease Digestive 1.09 0.998 – 1.18 0.0552 580 6626 exclusion phecode
571.51 Cirrhosis of liver without mention of alcohol Digestive 0.969 0.702 – 1.34 0.849 38 392 exclusion phecode
571.6 Primary biliary cirrhosis Digestive 1.13 0.902 – 1.42 0.29 82 1072 exclusion phecode
571.8
Liver abscess and sequelae of chronic liver
Liver abscess and sequelae of chronic liver disease
 Digestive 1.03 0.915 – 1.17 0.591 288 3604 exclusion phecode
571.81 Portal hypertension Digestive 1.02 0.865 – 1.19 0.845 168 1993 exclusion phecode
572 Ascites (non malignant) Digestive 0.94 0.86 – 1.03 0.172 547 5834 exclusion phecode
573 Other disorders of liver Digestive 1.02 0.932 – 1.12 0.656 521 5754 exclusion phecode
573.2 Liver replaced by transplant Digestive 0.915 0.666 – 1.26 0.585 40 362 exclusion phecode
573.3 Hepatomegaly Digestive 1.16 0.932 – 1.45 0.181 80 1104 exclusion phecode
573.5 Jaundice (not of newborn) Digestive 1.06 0.941 – 1.19 0.353 332 3310 exclusion phecode
573.7 Abnormal results of function study of liver Digestive 1.09 1.02 – 1.15 0.00642 1248 13475 exclusion phecode
573.9 Abnormal serum enzyme levels Digestive 1.08 0.817 – 1.42 0.599 56 822 exclusion phecode
574 Cholelithiasis and cholecystitis Digestive 1.1 1.07 – 1.13 2.91e-12 6192 63120 exclusion phecode
574.1 Cholelithiasis Digestive 1.1 1.06 – 1.13 4.2e-10 5428 54888 exclusion phecode
574.11 Cholelithiasis with acute cholecystitis Digestive 1.12 1.03 – 1.23 0.00842 574 5936 exclusion phecode
574.12 Cholelithiasis with other cholecystitis Digestive 1.08 1.03 – 1.13 0.000633 2201 22145 exclusion phecode
574.2 Calculus of bile duct Digestive 1.13 1.06 – 1.21 0.00032 972 10568 exclusion phecode
574.3 Cholecystitis without cholelithiasis Digestive 1.1 1.03 – 1.17 0.00519 1002 10999 exclusion phecode
575 Other biliary tract disease Digestive 1.07 1.02 – 1.13 0.0117 1479 15316 exclusion phecode
575.1 Cholangitis Digestive 0.988 0.847 – 1.15 0.873 183 1802 exclusion phecode
575.2 Obstruction of bile duct Digestive 1.08 0.952 – 1.22 0.236 277 2903 exclusion phecode
575.6 Cholesterolosis of gallbladder Digestive 1.07 0.92 – 1.24 0.387 205 1869 exclusion phecode
575.7 Other disorders of gallbladder Digestive 1.05 0.957 – 1.14 0.323 554 5685 exclusion phecode
575.8 Other disorders of biliary tract Digestive 1.11 0.993 – 1.23 0.0666 373 4188 exclusion phecode
575.9
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of biliary tract
 Digestive 1.17 0.972 – 1.41 0.0978 116 1434 exclusion phecode
577 Diseases of pancreas Digestive 1.05 0.986 – 1.13 0.121 944 10234 exclusion phecode
577.1 Acute pancreatitis Digestive 1.11 1.02 – 1.19 0.0102 732 7711 exclusion phecode
577.2 Chronic pancreatitis Digestive 1.13 0.948 – 1.34 0.173 136 1885 exclusion phecode
577.3 Cyst and pseudocyst of pancreas Digestive 1.01 0.826 – 1.24 0.92 106 1390 exclusion phecode
578 Gastrointestinal hemorrhage Digestive 1.06 1.03 – 1.09 2.32e-06 7495 80360 exclusion phecode
578.1 Hematemesis Digestive 1.1 1.01 – 1.2 0.0309 577 7486 exclusion phecode
578.2 Blood in stool Digestive 1.09 1.01 – 1.17 0.0181 857 9960 exclusion phecode
578.8 Hemorrhage of rectum and anus Digestive 1.05 1.02 – 1.08 0.000987 4919 51643 exclusion phecode
578.9 Hemorrhage of gastrointestinal tract Digestive 1.08 1.03 – 1.13 0.00189 1900 20334 exclusion phecode
579 Other symptoms involving abdomen and pelvis Digestive 0.981 0.9 – 1.07 0.672 575 6199 exclusion phecode
579.2 Splenomegaly Digestive 1.07 0.904 – 1.27 0.426 147 1592 exclusion phecode
579.8 Nonspecific abnormal findings in stool contents Digestive 1.01 0.93 – 1.1 0.795 613 6451 exclusion phecode
580 Nephritis; nephrosis; renal sclerosis Genitourinary 1.1 0.999 – 1.2 0.0513 502 5744 exclusion phecode
580.1 Glomerulonephritis Genitourinary 1.16 1.04 – 1.3 0.00787 348 3934 exclusion phecode
580.11 Proliferative glomerulonephritis Genitourinary 1.26 0.858 – 1.84 0.241 28 245 exclusion phecode
580.12 Non-proliferative glomerulonephritis Genitourinary 1.11 0.83 – 1.48 0.487 52 549 exclusion phecode
580.14 Chronic glomerulonephritis, NOS Genitourinary 1.15 1.01 – 1.3 0.0303 281 3254 exclusion phecode
580.2
Nephrotic syndrome without mention of
Nephrotic syndrome without mention of glomerulonephritis
 Genitourinary 1.14 0.968 – 1.34 0.117 155 1728 exclusion phecode
580.3
Nephritis and nephropathy without mention of
Nephritis and nephropathy without mention of glomerulonephritis
 Genitourinary 1.08 0.846 – 1.38 0.537 70 925 exclusion phecode
580.32
Nephritis and nephropathy with pathological
Nephritis and nephropathy with pathological lesion
 Genitourinary 1.04 0.819 – 1.31 0.762 75 941 exclusion phecode
585 Renal failure Genitourinary 1.06 1.02 – 1.11 0.00827 2195 25450 exclusion phecode
585.1 Acute renal failure Genitourinary 1.06 1 – 1.12 0.0441 1369 16434 exclusion phecode
585.2 Renal failure NOS Genitourinary 1.02 0.926 – 1.12 0.708 483 5310 exclusion phecode
585.3 Chronic renal failure [CKD] Genitourinary 1.11 1.03 – 1.19 0.00404 868 9686 exclusion phecode
585.31 Renal dialysis Genitourinary 1.27 1.09 – 1.48 0.00237 180 1861 exclusion phecode
586 Other disorders of the kidney and ureters Genitourinary 1.04 0.982 – 1.11 0.166 1120 12492 exclusion phecode
586.1 Anatomical abnormatilies of kidney and ureters Genitourinary 1.21 0.949 – 1.54 0.124 69 789 exclusion phecode
586.11 Small kidney Genitourinary 1.19 0.928 – 1.53 0.169 61 693 exclusion phecode
586.2 Cyst of kidney, acquired Genitourinary 1.11 1 – 1.23 0.0438 406 4567 exclusion phecode
586.3 Vascular disorders of kidney/hypertrophy Genitourinary 1.2 0.76 – 1.88 0.439 19 304 exclusion phecode
586.4 Stricture/obstruction of ureter Genitourinary 1.02 0.908 – 1.14 0.75 324 3461 exclusion phecode
587 Kidney replaced by transpant Genitourinary 1.03 0.856 – 1.23 0.78 132 1367 exclusion phecode
588 Disorders resulting from impaired renal function Genitourinary 0.813 0.583 – 1.13 0.221 36 411 exclusion phecode
589 Abnormal results of function study of kidney Genitourinary 1.18 0.833 – 1.67 0.352 35 446 exclusion phecode
590 Pyelonephritis Genitourinary 1.13 1.03 – 1.24 0.0132 466 5488 exclusion phecode
591 Urinary tract infection Genitourinary 1.08 1.05 – 1.11 1.72e-06 4557 48269 exclusion phecode
592 Cystitis and urethritis Genitourinary 1.05 0.989 – 1.12 0.107 1082 11731 exclusion phecode
592.1 Cystitis Genitourinary 1.05 0.989 – 1.12 0.103 1067 11511 exclusion phecode
592.11 Acute cystitis Genitourinary 1.11 0.825 – 1.51 0.481 43 512 exclusion phecode
592.12 Chronic cystitis Genitourinary 1.08 0.959 – 1.21 0.207 305 3432 exclusion phecode
592.13 Chronic interstitial cystitis Genitourinary 1 0.818 – 1.23 0.971 112 1011 exclusion phecode
592.2 Urethritis and urethral syndrome Genitourinary 1.05 0.806 – 1.37 0.716 57 623 exclusion phecode
593 Hematuria Genitourinary 1.04 1.02 – 1.07 0.002 5708 59932 exclusion phecode
594 Urinary calculus Genitourinary 1.05 1.01 – 1.1 0.0182 2295 23140 exclusion phecode
594.1 Calculus of kidney Genitourinary 1.02 0.955 – 1.08 0.603 1121 11622 exclusion phecode
594.2 Calculus of lower urinary tract Genitourinary 1.02 0.899 – 1.17 0.713 254 2538 exclusion phecode
594.3 Calculus of ureter Genitourinary 1.1 1.02 – 1.18 0.0084 877 8747 exclusion phecode
594.8 Renal colic Genitourinary 1.07 0.997 – 1.16 0.0612 768 7438 exclusion phecode
595 Hydronephrosis Genitourinary 1.04 0.962 – 1.13 0.315 723 7056 exclusion phecode
596 Other disorders of bladder Genitourinary 1.01 0.974 – 1.05 0.574 3309 34896 exclusion phecode
596.1 Bladder neck obstruction Genitourinary 1.02 0.941 – 1.11 0.624 666 6298 exclusion phecode
596.5 Functional disorders of bladder Genitourinary 1.08 0.99 – 1.18 0.0838 567 6365 exclusion phecode
597 Other disorders of urethra and urinary tract Genitourinary 1.08 1.02 – 1.14 0.00482 1480 14618 exclusion phecode
597.1 Urethral stricture (not specified as infectious) Genitourinary 1.08 1.02 – 1.15 0.0116 1256 12184 exclusion phecode
597.2 Urinary complications NEC Genitourinary 1.1 0.753 – 1.62 0.614 28 304 exclusion phecode
598 Abnormal findings on examination of urine Genitourinary 1.07 1 – 1.13 0.0358 1202 12799 exclusion phecode
598.9
Other nonspecific findings on examination of
Other nonspecific findings on examination of urine
 Genitourinary 0.959 0.775 – 1.19 0.696 103 1119 exclusion phecode
599 Other symptoms/disorders or the urinary system Genitourinary 1.06 1.03 – 1.08 2.58e-05 6843 71868 exclusion phecode
599.1 Urinary obstruction Genitourinary 0.936 0.721 – 1.21 0.619 60 576 exclusion phecode
599.2 Retention of urine Genitourinary 1.03 0.985 – 1.08 0.19 2226 22837 exclusion phecode
599.3 Dysuria Genitourinary 0.981 0.887 – 1.08 0.71 417 4622 exclusion phecode
599.4 Urinary incontinence Genitourinary 1.05 1.02 – 1.09 0.00423 3480 36870 exclusion phecode
599.5 Frequency of urination and polyuria Genitourinary 1.06 1 – 1.12 0.0394 1484 15081 exclusion phecode
599.6 Oliguria and anuria Genitourinary 1.56 1.05 – 2.32 0.0279 31 369 exclusion phecode
599.8 Other symptoms involving urinary system Genitourinary 1.19 0.822 – 1.73 0.353 29 238 exclusion phecode
599.9 Other abnormality of urination Genitourinary 1.09 1 – 1.18 0.0446 667 6813 exclusion phecode
600 Hyperplasia of prostate Genitourinary 1.02 0.985 – 1.06 0.25 3475 27554 exclusion phecode
601 Inflammatory diseases of prostate Genitourinary 0.949 0.877 – 1.03 0.196 709 6729 exclusion phecode
601.1 Prostatitis Genitourinary 0.924 0.845 – 1.01 0.0856 551 4940 exclusion phecode
601.11 Acute prostatitis Genitourinary 0.934 0.751 – 1.16 0.54 91 760 exclusion phecode
601.12 Chronic prostatitis Genitourinary 0.941 0.837 – 1.06 0.309 312 2846 exclusion phecode
601.3 Orchitis and epididymitis Genitourinary 1.39 0.851 – 2.25 0.189 17 217 exclusion phecode
601.4 Balanoposthitis Genitourinary 1.02 0.825 – 1.26 0.862 92 956 exclusion phecode
601.8
Other inflammatory disorders of male genital
Other inflammatory disorders of male genital organs
 Genitourinary 1.02 0.817 – 1.26 0.892 88 1018 exclusion phecode
602 Other disorders of prostate Genitourinary 1.04 0.945 – 1.15 0.4 435 4154 exclusion phecode
603 Other disorders of testis Genitourinary 1.03 0.952 – 1.12 0.462 683 7271 exclusion phecode
603.1 Hydrocele Genitourinary 0.984 0.891 – 1.09 0.749 424 4371 exclusion phecode
604 Disorders of penis Genitourinary 1.05 0.987 – 1.12 0.121 1108 11237 exclusion phecode
604.1 Redundant prepuce and phimosis/BXO Genitourinary 1.06 0.992 – 1.14 0.0852 939 9318 exclusion phecode
605 Erectile dysfunction [ED] Genitourinary 0.953 0.735 – 1.24 0.718 68 900 exclusion phecode
608 Other disorders of male genital organs Genitourinary 1.04 0.968 – 1.11 0.313 961 9451 exclusion phecode
609 Male infertility and abnormal spermatozoa Genitourinary 1.47 1.17 – 1.86 0.00099 79 684 exclusion phecode
609.1 Infertility, male Genitourinary 1.21 0.847 – 1.74 0.291 32 261 exclusion phecode
609.2 Abnormal spermatozoa Genitourinary 1.5 1.14 – 1.98 0.00384 55 508 exclusion phecode
610 Benign mammary dysplasias Genitourinary 1.08 1.01 – 1.15 0.0185 1059 10940 exclusion phecode
610.1 Cystic mastopathy Genitourinary 1.02 0.921 – 1.14 0.67 391 4089 exclusion phecode
610.2 Fibroadenosis of breast Genitourinary 1.07 0.899 – 1.28 0.439 134 1331 exclusion phecode
610.3 Fibrosclerosis of breast Genitourinary 1.22 0.997 – 1.48 0.053 112 1337 exclusion phecode
610.4 Benign neoplasm of breast Genitourinary 1.07 0.983 – 1.16 0.118 607 6147 exclusion phecode
610.8 Other specified benign mammary dysplasias Genitourinary 1.05 0.93 – 1.19 0.423 290 3060 exclusion phecode
611 Abnormal findings on mammogram or breast exam Genitourinary 0.979 0.901 – 1.06 0.606 649 6744 exclusion phecode
611.1 Abnormal mammogram Genitourinary 1.2 0.78 – 1.85 0.405 22 231 exclusion phecode
611.3 Lump or mass in breast Genitourinary 0.978 0.899 – 1.06 0.593 630 6564 exclusion phecode
612
Breast conditions, congenital or relating to
Breast conditions, congenital or relating to hormones
 Genitourinary 1.18 1.05 – 1.31 0.00352 362 3760 exclusion phecode
612.2 Hypertrophy of breast (Gynecomastia) Genitourinary 1.18 1.05 – 1.32 0.0042 342 3555 exclusion phecode
612.3 Congenital anomalies of breast Genitourinary – 31 320 exclusion phecode
613 Other nonmalignant breast conditions Genitourinary 1.06 0.978 – 1.15 0.153 647 7231 exclusion phecode
613.1 Inflammatory disease of breast Genitourinary 1.05 0.924 – 1.19 0.456 265 3132 exclusion phecode
613.5 Mastodynia Genitourinary 1.13 0.763 – 1.68 0.538 30 332 exclusion phecode
613.7 Other signs and symptoms in breast Genitourinary – 296 3055 exclusion phecode
613.8 Other specified disorders of breast Genitourinary – 124 1440 exclusion phecode
613.9 Breast disorder NOS Genitourinary – 92 925 exclusion phecode
614 Inflammatory diseases of female pelvic organs Genitourinary 1.03 0.987 – 1.08 0.175 2369 25426 exclusion phecode
614.1
Pelvic peritoneal adhesions, female
Pelvic peritoneal adhesions, female (postoperative) (postinfection)
 Genitourinary 1.04 0.978 – 1.11 0.207 1081 11390 exclusion phecode
614.3 Pelvic inflammatory disease (PID) Genitourinary 1.03 0.913 – 1.16 0.661 321 3786 exclusion phecode
614.31 Acute inflammatory pelvic disease Genitourinary 0.817 0.531 – 1.26 0.359 22 262 exclusion phecode
614.32 Chronic inflammatory pelvic disease Genitourinary 1.05 0.879 – 1.25 0.609 145 1891 exclusion phecode
614.33 Pelvic inflammatory disease, NOS Genitourinary 0.856 0.718 – 1.02 0.0845 141 1600 exclusion phecode
614.4 Inflammatory diseases of uterus, except cervix Genitourinary 1 0.831 – 1.2 0.996 131 1230 exclusion phecode
614.5
Inflammatory disease of cervix, vagina, and
Inflammatory disease of cervix, vagina, and vulva
 Genitourinary 1.01 0.944 – 1.07 0.83 1046 11387 exclusion phecode
614.51 Cervicitis and endocervicitis Genitourinary 0.966 0.884 – 1.06 0.443 568 5826 exclusion phecode
614.52 Vaginitis and vulvovaginitis Genitourinary 1.02 0.872 – 1.18 0.841 181 1857 exclusion phecode
614.53 Cyst or abscess of Bartholin's gland Genitourinary 1.08 0.966 – 1.22 0.171 314 3348 exclusion phecode
614.54 Abscess or ulceration of vulva Genitourinary 1.09 0.864 – 1.38 0.461 73 1206 exclusion phecode
615 Endometriosis Genitourinary 1.11 1.06 – 1.17 3.18e-05 1843 18054 exclusion phecode
617
Disorders secondary to childbirth, surgery
Disorders secondary to childbirth, surgery, trauma
 Genitourinary 1.04 0.855 – 1.27 0.695 115 1364 exclusion phecode
618 Genital prolapse Genitourinary 1.04 1.01 – 1.07 0.00429 5160 50543 exclusion phecode
618.1 Prolapse of vaginal walls Genitourinary 1.06 1.02 – 1.1 0.00238 3197 31982 exclusion phecode
618.2 Uterine/Uterovaginal prolapse Genitourinary 1.01 0.973 – 1.06 0.5 2439 23450 exclusion phecode
618.5 Prolapse of vaginal vault after hysterectomy Genitourinary 1.03 0.897 – 1.18 0.687 233 2250 exclusion phecode
618.6 Vaginal enterocele, congenital or acquired Genitourinary 1.06 0.937 – 1.2 0.36 297 2981 exclusion phecode
619 Noninflammatory female genital disorders Genitourinary 1.03 0.997 – 1.07 0.0727 3784 38487 exclusion phecode
619.1
Noninflammatory disorders of ovary, fallopian
Noninflammatory disorders of ovary, fallopian tube, and broad ligament
 Genitourinary 1.01 0.9 – 1.14 0.836 324 3180 exclusion phecode
619.2 Disorders of uterus, NEC Genitourinary 1.02 0.962 – 1.07 0.582 1482 14593 exclusion phecode
619.3 Noninflammatory disorders of cervix Genitourinary 1.03 0.972 – 1.09 0.304 1289 12593 exclusion phecode
619.4 Noninflammatory disorders of vagina Genitourinary 1.03 0.953 – 1.11 0.472 748 7865 exclusion phecode
619.5 Noninflammatory disorders of vulva and perineum Genitourinary 1.03 0.944 – 1.13 0.482 535 5927 exclusion phecode
620 Dysplasia of female genital organs Genitourinary 0.96 0.652 – 1.41 0.835 27 299 exclusion phecode
621 Endometrial hyperplasia Genitourinary 1.02 0.925 – 1.12 0.726 501 4957 exclusion phecode
622 Polyp of female genital organs Genitourinary 0.999 0.969 – 1.03 0.96 4790 45430 exclusion phecode
622.1 Polyp of corpus uteri Genitourinary 0.989 0.955 – 1.03 0.552 3532 34125 exclusion phecode
622.2 Mucous polyp of cervix Genitourinary 1.03 0.979 – 1.09 0.252 1675 14857 exclusion phecode
623 Hypertrophy of female genital organs Genitourinary 1.06 0.973 – 1.16 0.181 605 5679 exclusion phecode
624 Symptoms involving female genital tract Genitourinary 0.985 0.884 – 1.1 0.786 363 3438 exclusion phecode
624.1 Dystrophy of female genital tract Genitourinary 0.924 0.758 – 1.13 0.436 109 1014 exclusion phecode
624.2 Atrophy of female genital tract Genitourinary 0.998 0.862 – 1.16 0.976 191 1845 exclusion phecode
624.9 stress incontinence, female Genitourinary 1.08 1.03 – 1.13 0.000421 2425 25429 exclusion phecode
625
Pain and other symptoms associated with female
Pain and other symptoms associated with female genital organs
 Genitourinary 1.08 1.02 – 1.15 0.00819 1238 12843 exclusion phecode
625.1 Dyspareunia Genitourinary 1.06 0.971 – 1.17 0.183 515 5319 exclusion phecode
626
Disorders of menstruation and other abnormal
Disorders of menstruation and other abnormal bleeding from female genital tract
 Genitourinary 1.06 1.04 – 1.09 2.07e-06 7178 50722 exclusion phecode
626.1 Irregular menstrual cycle/bleeding Genitourinary 1.07 1.04 – 1.1 1.39e-06 6269 48584 exclusion phecode
626.11 Absent or infrequent menstruation Genitourinary 1.37 1.01 – 1.85 0.0416 48 486 exclusion phecode
626.12 Excessive or frequent menstruation Genitourinary 1.06 1.03 – 1.1 0.000196 4270 40797 exclusion phecode
626.13 Irregular menstrual cycle Genitourinary 1.07 0.993 – 1.15 0.0795 866 8783 exclusion phecode
626.14 Irregular menstrual bleeding Genitourinary 1.05 1 – 1.11 0.0495 1722 16950 exclusion phecode
626.2 Dysmenorrhea Genitourinary 1.15 1.06 – 1.24 0.000527 715 8005 exclusion phecode
626.4 Premenstrual tension syndromes Genitourinary 1.13 0.856 – 1.48 0.395 57 690 exclusion phecode
626.8 Infertility, female Genitourinary 1.02 0.943 – 1.11 0.574 646 6174 exclusion phecode
627 Menopausal and postmenopausal disorders Genitourinary 1.03 0.999 – 1.06 0.0557 4535 44804 exclusion phecode
627.1 Postmenopausal bleeding Genitourinary 1.02 0.991 – 1.06 0.153 3903 38949 exclusion phecode
627.2 Symptomatic menopause Genitourinary 1.01 0.802 – 1.28 0.922 77 801 exclusion phecode
627.3 Postmenopausal atrophic vaginitis Genitourinary 1.03 0.937 – 1.12 0.579 540 4725 exclusion phecode
627.4 Premenopausal menorrhagia Genitourinary 1.06 0.886 – 1.27 0.514 140 1391 exclusion phecode
628 Ovarian cyst Genitourinary 1.12 1.07 – 1.18 7.87e-07 2054 21028 exclusion phecode
634 Miscarriage; stillbirth Pregnancy Complications 0.976 0.933 – 1.02 0.307 2172 16790 exclusion phecode
634.1 Missed abortion/Hydatidiform mole Pregnancy Complications 0.959 0.874 – 1.05 0.379 509 5239 exclusion phecode
634.3 Ectopic pregnancy Pregnancy Complications 1.12 0.934 – 1.34 0.224 136 1530 exclusion phecode
635
Hemorrhage during pregnancy; childbirth and
Hemorrhage during pregnancy; childbirth and postpartum
 Pregnancy Complications 0.968 0.901 – 1.04 0.37 866 7906 exclusion phecode
635.2
Antepartum hemorrhage, abruptio placentae, and
Antepartum hemorrhage, abruptio placentae, and placenta previa
 Pregnancy Complications 0.987 0.883 – 1.1 0.819 366 3873 exclusion phecode
635.3 Placenta previa and abruptio placenta Pregnancy Complications 0.941 0.862 – 1.03 0.174 568 5611 exclusion phecode
636
Early or threatened labor; hemorrhage in early
Early or threatened labor; hemorrhage in early pregnancy
 Pregnancy Complications 1.05 0.985 – 1.12 0.128 1027 9077 exclusion phecode
636.2 Early onset of delivery Pregnancy Complications 0.954 0.839 – 1.08 0.469 267 2801 exclusion phecode
636.3 Hemorrhage in early pregnancy Pregnancy Complications 1.06 0.958 – 1.16 0.277 479 4879 exclusion phecode
638 Other high-risk pregnancy Pregnancy Complications 0.77 0.527 – 1.13 0.178 29 323 exclusion phecode
642
Hypertension complicating pregnancy
Hypertension complicating pregnancy, childbirth, and the puerperium
 Pregnancy Complications 1.08 0.984 – 1.19 0.104 496 5008 exclusion phecode
642.1 Preeclampsia and eclampsia Pregnancy Complications 1.04 0.872 – 1.24 0.661 135 1373 exclusion phecode
643 Excessive vomiting in pregnancy Pregnancy Complications 1.05 0.861 – 1.28 0.637 108 946 exclusion phecode
643.1 Hyperemesis gravidarum Pregnancy Complications 1.04 0.83 – 1.3 0.739 82 666 exclusion phecode
645 Late pregnancy and failed induction Pregnancy Complications 1.06 0.964 – 1.15 0.245 524 5576 exclusion phecode
646 Other complications of pregnancy NEC Pregnancy Complications 1.05 0.983 – 1.13 0.141 930 9386 exclusion phecode
647
Infectious and parasitic complications
Infectious and parasitic complications affecting pregnancy
 Pregnancy Complications 0.769 0.539 – 1.1 0.148 34 303 exclusion phecode
647.1
Infections of genitourinary tract during
Infections of genitourinary tract during pregnancy
 Pregnancy Complications 1.1 0.915 – 1.32 0.315 125 1258 exclusion phecode
649
Other conditions or status of the mother
Other conditions or status of the mother complicating pregnancy, childbirth, or the puerperium
 Pregnancy Complications 1.08 0.808 – 1.45 0.595 45 497 exclusion phecode
649.1
Diabetes or abnormal glucose tolerance
Diabetes or abnormal glucose tolerance complicating pregnancy
 Pregnancy Complications 1.13 0.92 – 1.39 0.242 94 871 exclusion phecode
650 Normal delivery Pregnancy Complications 0.99 0.922 – 1.06 0.79 856 8476 exclusion phecode
651 Multiple gestation Pregnancy Complications 1.09 0.915 – 1.29 0.342 146 1544 exclusion phecode
652
Malposition and malpresentation of fetus or
Malposition and malpresentation of fetus or obstruction
 Pregnancy Complications 0.969 0.898 – 1.05 0.416 753 7423 exclusion phecode
653
Problems associated with amniotic cavity and
Problems associated with amniotic cavity and membranes
 Pregnancy Complications 0.869 0.798 – 0.946 0.00125 602 6048 exclusion phecode
654
Other and unspecified complications of birth
Other and unspecified complications of birth; puerperium affecting management of mother
 Pregnancy Complications 0.849 0.592 – 1.22 0.375 29 330 exclusion phecode
655
Known or suspected fetal abnormality affecting
Known or suspected fetal abnormality affecting management of mother
 Pregnancy Complications 0.948 0.902 – 0.997 0.0369 1830 13414 exclusion phecode
656 Other perinatal conditions of fetus or newborn Pregnancy Complications 0.861 0.632 – 1.17 0.344 46 463 exclusion phecode
661 Fetal distress and abnormal forces of labor Pregnancy Complications 0.932 0.871 – 0.998 0.0451 956 8419 exclusion phecode
663
Umbilical cord complications during labor and
Umbilical cord complications during labor and delivery
 Pregnancy Complications 0.976 0.852 – 1.12 0.721 236 2370 exclusion phecode
665 Obstetrical/birth trauma Pregnancy Complications 0.931 0.89 – 0.974 0.00181 2389 13511 exclusion phecode
669 Complications of labor and delivery NEC Pregnancy Complications 0.9 0.845 – 0.959 0.00108 1114 9615 exclusion phecode
671
Venous/cerebrovascular complications embolism
Venous/cerebrovascular complications embolism in pregnancy and the puerperium
 Pregnancy Complications 1.17 0.901 – 1.52 0.24 66 758 exclusion phecode
674 Other complications of the puerperium NEC Pregnancy Complications 1.14 0.938 – 1.39 0.187 118 1163 exclusion phecode
676
Other disorders of the breast associated with
Other disorders of the breast associated with childbirth and disorders of lactation
 Pregnancy Complications 1.07 0.728 – 1.56 0.742 32 288 exclusion phecode
679 Complications of in utero procedures Dermatologic 0.784 0.554 – 1.11 0.169 31 262 exclusion phecode
681 Superficial cellulitis and abscess Dermatologic 1.1 1.05 – 1.14 1.42e-05 2545 27582 exclusion phecode
681.1 Cellulitis and abscess of fingers/toes Dermatologic 1.17 1.01 – 1.34 0.0321 221 2086 exclusion phecode
681.2 Cellulitis and abscess of face/neck Dermatologic 1.04 0.89 – 1.21 0.631 177 2094 exclusion phecode
681.3 Cellulitis and abscess of arm/hand Dermatologic 1.09 1.04 – 1.15 0.000285 1900 20785 exclusion phecode
681.5 Cellulitis and abscess of leg, except foot Dermatologic 1.09 1.04 – 1.14 0.000406 1911 20789 exclusion phecode
681.6 Cellulitis and abscess of foot, toe Dermatologic 1.09 1.04 – 1.15 0.000356 1892 20618 exclusion phecode
681.7 Cellulitis and abscess of trunk Dermatologic 1.11 0.966 – 1.28 0.141 224 2405 exclusion phecode
686
Other local infections of skin and subcutaneous
Other local infections of skin and subcutaneous tissue
 Dermatologic 1.1 0.998 – 1.21 0.0545 472 5198 exclusion phecode
686.1 Carbuncle and furuncle Dermatologic 1.05 0.973 – 1.13 0.211 727 8934 exclusion phecode
686.3 Pilonidal cyst Dermatologic 1.22 1.04 – 1.43 0.0172 159 2278 exclusion phecode
686.4 Pyogenic granuloma Dermatologic 0.99 0.844 – 1.16 0.897 162 1378 exclusion phecode
687 Symptoms affecting skin Dermatologic 1.04 0.896 – 1.2 0.61 198 2063 exclusion phecode
687.1 Rash and other nonspecific skin eruption Dermatologic 1.04 0.963 – 1.12 0.337 793 8354 exclusion phecode
687.2 Localized superficial swelling, mass, or lump Dermatologic 1.03 0.842 – 1.26 0.766 105 1090 exclusion phecode
687.3 Changes in skin texture Dermatologic 1.13 0.816 – 1.57 0.46 41 409 exclusion phecode
687.4 Disturbance of skin sensation Dermatologic 1.08 1.02 – 1.15 0.0127 1072 11502 exclusion phecode
689 Disorder of skin and subcutaneous tissue NOS Dermatologic 1.03 0.988 – 1.08 0.152 2158 22321 exclusion phecode
690 Erythematosquamous dermatosis Dermatologic 1.16 0.782 – 1.73 0.455 22 264 exclusion phecode
690.1 Seborrheic dermatitis Dermatologic 1.21 0.756 – 1.92 0.432 17 196 exclusion phecode
691 Congenital anomalies of skin Dermatologic 1.24 0.933 – 1.64 0.139 50 449 exclusion phecode
694 Dyschromia and Vitiligo Dermatologic 1.03 0.923 – 1.14 0.64 405 3830 exclusion phecode
694.1 Vitiligo Dermatologic 1.17 0.77 – 1.79 0.456 27 240 exclusion phecode
694.2 Other dyschromia Dermatologic 1.02 0.909 – 1.15 0.697 317 3098 exclusion phecode
694.3 Vascular disorders of skin Dermatologic 0.901 0.667 – 1.22 0.497 50 418 exclusion phecode
695 Erythematous conditions Dermatologic 1.09 1.01 – 1.17 0.0194 898 9548 exclusion phecode
695.1 Toxic erythema Dermatologic 1.28 0.911 – 1.81 0.154 36 432 exclusion phecode
695.2 Bullous dermatoses Dermatologic 1.35 0.995 – 1.83 0.0535 43 518 exclusion phecode
695.21 Dermatitis herpetiformis Dermatologic 0.989 0.604 – 1.62 0.966 15 210 exclusion phecode
695.22 Pemphigus and pemphigoid Dermatologic 1.44 0.971 – 2.13 0.0698 27 293 exclusion phecode
695.3 Rosacea Dermatologic 1.23 1.02 – 1.49 0.0312 119 1177 exclusion phecode
695.4 Lupus (localized and systemic) Dermatologic 1.08 0.911 – 1.27 0.385 159 1766 exclusion phecode
695.41 Cutaneous lupus erythematosus Dermatologic 1.04 0.755 – 1.44 0.796 42 566 exclusion phecode
695.42 Systemic lupus erythematosus Dermatologic 1.09 0.913 – 1.31 0.335 138 1480 exclusion phecode
695.7 Prurigo and Lichen Dermatologic 1.16 1.02 – 1.3 0.0185 294 3133 exclusion phecode
695.8 Other specified erythematous conditions Dermatologic 1.05 0.846 – 1.31 0.646 91 988 exclusion phecode
695.81 Erythema nodosum Dermatologic 0.959 0.67 – 1.37 0.821 31 314 exclusion phecode
695.9 Unspecified erythematous condition Dermatologic 0.921 0.791 – 1.07 0.289 188 1805 exclusion phecode
696 Psoriasis and related disorders Dermatologic 1.02 0.937 – 1.1 0.7 647 8661 exclusion phecode
696.4 Psoriasis Dermatologic 1.01 0.929 – 1.09 0.847 633 8471 exclusion phecode
696.41 Psoriasis vulgaris Dermatologic 0.974 0.884 – 1.07 0.596 442 6443 exclusion phecode
696.42 Psoriatic arthropathy Dermatologic 1.07 0.939 – 1.23 0.302 242 2783 exclusion phecode
697 Sarcoidosis Dermatologic 1.08 0.95 – 1.23 0.238 259 2129 exclusion phecode
698 Pruritus and related conditions Dermatologic 1.03 0.906 – 1.16 0.693 286 3056 exclusion phecode
700 Corns and callosities Dermatologic 1.28 1.04 – 1.59 0.0202 99 1234 exclusion phecode
701
Other hypertrophic and atrophic conditions of
Other hypertrophic and atrophic conditions of skin
 Dermatologic 1.06 1.01 – 1.11 0.0309 1752 18530 exclusion phecode
701.1 Keratoderma, acquired Dermatologic 0.949 0.667 – 1.35 0.771 33 330 exclusion phecode
701.2 Scar conditions and fibrosis of skin Dermatologic 1.05 0.982 – 1.13 0.144 886 9336 exclusion phecode
701.3 Circumscribed scleroderma Dermatologic 0.906 0.575 – 1.43 0.671 17 270 exclusion phecode
701.4 Keloid scar Dermatologic 1.24 0.982 – 1.56 0.0711 85 928 exclusion phecode
701.5 Abnormal granulation tissue Dermatologic 0.955 0.818 – 1.12 0.56 185 1830 exclusion phecode
701.6 Acquired acanthosis nigricans Dermatologic 1.19 0.85 – 1.67 0.31 37 376 exclusion phecode
702
Degenerative skin conditions and other
Degenerative skin conditions and other dermatoses
 Dermatologic 1.01 0.969 – 1.06 0.538 2092 20624 exclusion phecode
702.1 Actinic keratosis Dermatologic 1.03 0.96 – 1.1 0.448 993 9713 exclusion phecode
702.2 Seborrheic keratosis Dermatologic 1.01 0.947 – 1.07 0.825 1175 11627 exclusion phecode
703 Diseases of nail, NOS Dermatologic 0.967 0.802 – 1.16 0.722 130 1371 exclusion phecode
703.1 Ingrowing nail Dermatologic 1.08 0.967 – 1.2 0.174 378 3807 exclusion phecode
704 Diseases of hair and hair follicles Dermatologic 1.07 1.02 – 1.12 0.00929 1865 20586 exclusion phecode
704.1 Alopecia Dermatologic 0.942 0.711 – 1.25 0.674 54 524 exclusion phecode
704.8
Other specified diseases of hair and hair
Other specified diseases of hair and hair follicles
 Dermatologic 1.31 0.896 – 1.92 0.163 32 296 exclusion phecode
705 Disorders of sweat glands Dermatologic 1.1 0.801 – 1.52 0.548 38 979 exclusion phecode
705.3 Hidradenitis Dermatologic 1.1 0.746 – 1.62 0.629 26 810 exclusion phecode
705.8 Hyperhidrosis Dermatologic 1.11 0.961 – 1.28 0.156 198 2246 exclusion phecode
706 Diseases of sebaceous glands Dermatologic 1.07 1.03 – 1.11 0.000403 2890 32610 exclusion phecode
706.1 Acne Dermatologic 1.25 0.859 – 1.81 0.247 30 307 exclusion phecode
706.2 Sebaceous cyst Dermatologic 1.06 1.02 – 1.1 0.00124 3065 34439 exclusion phecode
707 Chronic ulcer of skin Dermatologic 1.09 1 – 1.18 0.05 606 7266 exclusion phecode
707.1 Decubitus ulcer Dermatologic 1.22 1.08 – 1.39 0.00218 264 3340 exclusion phecode
709 Diffuse diseases of connective tissue Dermatologic 1.11 1.04 – 1.18 0.00062 1302 13710 exclusion phecode
709.2 Sicca syndrome Dermatologic 1.11 0.96 – 1.28 0.16 223 2097 exclusion phecode
709.3 Systemic sclerosis Dermatologic 1.07 0.822 – 1.4 0.604 66 738 exclusion phecode
709.6
Other specified diffuse diseases of connective
Other specified diffuse diseases of connective tissue
 Dermatologic 1.34 0.93 – 1.93 0.117 29 278 exclusion phecode
709.7 Unspecified diffuse connective tissue disease Dermatologic 1.11 1.04 – 1.18 0.003 1010 10791 exclusion phecode
710
Osteomyelitis, periostitis, and other
Osteomyelitis, periostitis, and other infections involving bone
 Musculoskeletal 1.16 0.998 – 1.36 0.0534 186 2243 exclusion phecode
710.1 Osteomyelitis Musculoskeletal 1.15 0.981 – 1.35 0.0849 175 2070 exclusion phecode
710.12 Chronic osteomyelitis Musculoskeletal 1.25 0.963 – 1.63 0.0934 58 718 exclusion phecode
710.19 Unspecified osteomyelitis Musculoskeletal 1.14 0.946 – 1.38 0.166 131 1469 exclusion phecode
711 Arthropathy associated with infections Musculoskeletal 1.19 1 – 1.41 0.0496 163 1549 exclusion phecode
711.1 Pyogenic arthritis Musculoskeletal 1.3 1.07 – 1.58 0.0088 122 1217 exclusion phecode
712 Infective connective tissue disorders Musculoskeletal 1.17 0.787 – 1.73 0.439 26 304 exclusion phecode
713
Arthropathy associated with other disorders
Arthropathy associated with other disorders classified elsewhere
 Musculoskeletal 1 0.754 – 1.33 0.997 53 560 exclusion phecode
713.5
Arthropathy associated with neurological
Arthropathy associated with neurological disorders
 Musculoskeletal 1.05 0.649 – 1.71 0.836 19 231 exclusion phecode
714
Rheumatoid arthritis and other inflammatory
Rheumatoid arthritis and other inflammatory polyarthropathies
 Musculoskeletal 1.1 1.05 – 1.16 0.000241 1625 19767 exclusion phecode
714.1 Rheumatoid arthritis Musculoskeletal 1.11 1.05 – 1.18 0.000102 1473 17976 exclusion phecode
715 Other inflammatory spondylopathies Musculoskeletal 1.06 0.973 – 1.16 0.175 545 6510 exclusion phecode
715.1 Sacroiliitis NEC Musculoskeletal 0.962 0.725 – 1.28 0.79 53 472 exclusion phecode
715.2 Ankylosing spondylitis Musculoskeletal 0.94 0.809 – 1.09 0.417 182 2337 exclusion phecode
716 Other arthropathies Musculoskeletal 1.12 1.1 – 1.14 3.56e-33 13471 104203 exclusion phecode
716.1 Unspecified polyarthropathy or polyarthritis Musculoskeletal 1.2 1.13 – 1.27 1.22e-09 1280 13847 exclusion phecode
716.2 Unspecified monoarthritis Musculoskeletal 1.13 1.1 – 1.17 2.89e-19 5767 59651 exclusion phecode
716.9 Arthropathy NOS Musculoskeletal 1.12 1.1 – 1.14 8.22e-33 12913 102877 exclusion phecode
717 Polymyalgia Rheumatica Musculoskeletal 1.1 0.988 – 1.21 0.0821 413 4392 exclusion phecode
720 Spinal stenosis Musculoskeletal 1.12 1.05 – 1.19 0.000272 1202 14119 exclusion phecode
721 Spondylosis and allied disorders Musculoskeletal 1.13 1.08 – 1.17 5.74e-09 2752 30772 exclusion phecode
721.1 Spondylosis without myelopathy Musculoskeletal 1.12 1.06 – 1.18 1.26e-05 1745 19836 exclusion phecode
721.2 Spondylosis with myelopathy Musculoskeletal 0.985 0.76 – 1.28 0.909 54 736 exclusion phecode
721.8 Other allied disorders of spine Musculoskeletal 1.18 0.975 – 1.42 0.0907 132 1342 exclusion phecode
722 Intervertebral disc disorders Musculoskeletal 1.13 1.09 – 1.17 8.87e-11 3159 35831 exclusion phecode
722.1 Displacement of intervertebral disc Musculoskeletal 1.24 1.06 – 1.44 0.00816 173 2021 exclusion phecode
722.6 Degeneration of intervertebral disc Musculoskeletal 1.19 1.11 – 1.27 3.19e-07 1000 11396 exclusion phecode
722.8 Postlaminectomy syndrome Musculoskeletal 1.22 0.796 – 1.88 0.358 17 288 exclusion phecode
722.9 Other and unspecified disc disorder Musculoskeletal 1.09 1.03 – 1.15 0.00123 1553 17536 exclusion phecode
723 Other disorders of cervical region Musculoskeletal 1 0.852 – 1.18 0.97 161 2044 exclusion phecode
723.1 Torticollis Musculoskeletal 0.936 0.686 – 1.28 0.676 44 472 exclusion phecode
724 Other and unspecified disorders of back Musculoskeletal 1.14 1.05 – 1.23 0.00119 727 7997 exclusion phecode
724.1 Disorders of sacrum Musculoskeletal 1.08 0.915 – 1.29 0.349 145 1713 exclusion phecode
724.2 Disorders of coccyx Musculoskeletal 1.06 0.897 – 1.26 0.486 148 1728 exclusion phecode
724.8 Other symptoms referable to back Musculoskeletal 1.68 0.998 – 2.81 0.051 18 240 exclusion phecode
724.9 Other unspecified back disorders Musculoskeletal 1.15 1.05 – 1.26 0.0019 574 6160 exclusion phecode
726 Peripheral enthesopathies and allied syndromes Musculoskeletal 1.1 1.06 – 1.13 3.21e-10 5434 57467 exclusion phecode
726.1 Enthesopathy Musculoskeletal 1.08 1.04 – 1.12 1.94e-05 3603 37547 exclusion phecode
726.2 Synoviopathy Musculoskeletal 1.09 0.91 – 1.31 0.344 123 1349 exclusion phecode
726.3 Bursitis Musculoskeletal 1.07 0.947 – 1.2 0.286 314 3090 exclusion phecode
727 Other disorders of synovium, tendon, and bursa Musculoskeletal 1.09 1.05 – 1.14 1.66e-05 2775 29333 exclusion phecode
727.1 Synovitis and tenosynovitis Musculoskeletal 1.11 1.04 – 1.18 0.00227 1031 10956 exclusion phecode
727.2 Bursitis disorders Musculoskeletal 0.874 0.62 – 1.23 0.443 35 390 exclusion phecode
727.4 Ganglion and cyst of synovium, tendon, and bursa Musculoskeletal 1.1 1.03 – 1.16 0.00301 1205 12612 exclusion phecode
727.5 Rupture of synovium Musculoskeletal 1.07 0.928 – 1.24 0.35 205 2262 exclusion phecode
727.6 Rupture of tendon, nontraumatic Musculoskeletal 1.2 1.01 – 1.43 0.0433 137 1345 exclusion phecode
727.7 Contracture of tendon (sheath) Musculoskeletal 0.83 0.617 – 1.12 0.219 48 524 exclusion phecode
728 Disorders of muscle, ligament, and fascia Musculoskeletal 1.01 0.949 – 1.07 0.775 1143 12648 exclusion phecode
728.2 Laxity of ligament or hypermobility syndrome Musculoskeletal 0.935 0.796 – 1.1 0.418 159 1690 exclusion phecode
728.7 Fasciitis Musculoskeletal 1.02 0.96 – 1.08 0.521 1208 13193 exclusion phecode
728.71
Contracture of palmar fascia [Dupuytren's
Contracture of palmar fascia [Dupuytren's disease]
 Musculoskeletal 1.01 0.945 – 1.07 0.829 1068 11886 exclusion phecode
729 Other disorders of soft tissues Musculoskeletal 1.12 1.07 – 1.17 2.92e-07 2239 23837 exclusion phecode
729.1 Rheumatism, unspecified and fibrositis Musculoskeletal 1.07 0.96 – 1.19 0.231 389 4240 exclusion phecode
729.3 Panniculitis Musculoskeletal 1.1 0.79 – 1.53 0.57 37 423 exclusion phecode
731
Osteitis deformans and osteopathies associated
Osteitis deformans and osteopathies associated with other disorders classified elsewhere
 Musculoskeletal 1.18 0.971 – 1.43 0.0968 126 1116 exclusion phecode
731.1 Osteitis deformans [Paget's disease of bone] Musculoskeletal 1.22 1 – 1.48 0.0496 121 1076 exclusion phecode
732 Osteochondropathies Musculoskeletal 1.01 0.858 – 1.18 0.938 176 1853 exclusion phecode
732.1 Juvenile osteochondrosis Musculoskeletal 1.02 0.796 – 1.3 0.891 78 826 exclusion phecode
732.7 Osteochondritis dissecans Musculoskeletal 1.03 0.705 – 1.52 0.864 27 219 exclusion phecode
733 Other disorders of bone and cartilage Musculoskeletal 1.15 1.06 – 1.24 0.000845 669 7299 exclusion phecode
733.2 Cyst of bone Musculoskeletal 1.09 0.895 – 1.32 0.402 118 1300 exclusion phecode
733.4 Aseptic necrosis of bone Musculoskeletal 1.03 0.885 – 1.2 0.694 187 2143 exclusion phecode
733.6 Costochondritis Musculoskeletal 0.97 0.722 – 1.3 0.839 46 517 exclusion phecode
733.8 Malunion and nonunion of fracture Musculoskeletal 1.12 1.02 – 1.24 0.0231 430 4857 exclusion phecode
733.9 Chondromalacia Musculoskeletal 0.992 0.738 – 1.33 0.958 43 498 exclusion phecode
735 Acquired foot deformities Musculoskeletal 1.1 1.07 – 1.14 9.65e-09 3933 39935 exclusion phecode
735.1 Flat foot Musculoskeletal 1.22 0.933 – 1.59 0.147 61 765 exclusion phecode
735.2 Acquired toe deformities Musculoskeletal 1.09 1.04 – 1.14 0.000488 2042 20855 exclusion phecode
735.21 Hammer toe (acquired) Musculoskeletal 1.1 1.02 – 1.19 0.0117 796 8045 exclusion phecode
735.23 Hallux rigidus Musculoskeletal 1.04 0.959 – 1.13 0.327 643 6181 exclusion phecode
735.3 Hallux valgus (Bunion) Musculoskeletal 1.11 1.07 – 1.16 9.22e-08 2803 28016 exclusion phecode
736 Other acquired deformities of limbs Musculoskeletal 1.03 0.947 – 1.13 0.459 569 6306 exclusion phecode
736.2 Acquired deformities of finger Musculoskeletal 0.978 0.79 – 1.21 0.838 88 934 exclusion phecode
737 Curvature of spine Musculoskeletal 1.1 0.99 – 1.22 0.0784 417 4618 exclusion phecode
737.3 Kyphoscoliosis and scoliosis Musculoskeletal 1.07 0.963 – 1.19 0.202 388 4350 exclusion phecode
738 Other acquired musculoskeletal deformity Musculoskeletal 1.16 1.07 – 1.26 0.000308 653 7667 exclusion phecode
738.4 Acquired spondylolisthesis Musculoskeletal 1.14 1.04 – 1.25 0.0047 518 6111 exclusion phecode
739 Contracture of joint Musculoskeletal 1.12 0.953 – 1.31 0.169 173 1923 exclusion phecode
740 Osteoarthrosis Musculoskeletal 1.1 1.08 – 1.13 4.01e-20 10043 89432 exclusion phecode
740.1 Osteoarthritis; localized Musculoskeletal 1.09 1.06 – 1.12 1.16e-10 6479 65025 exclusion phecode
740.11 Osteoarthrosis, localized, primary Musculoskeletal 1.1 1.06 – 1.14 9.14e-08 3380 34356 exclusion phecode
740.12 Osteoarthrosis, localized, secondary Musculoskeletal 1.01 0.84 – 1.21 0.939 129 1337 exclusion phecode
740.2 Osteoarthrosis, generalized Musculoskeletal 1.23 1.07 – 1.41 0.00296 231 2309 exclusion phecode
740.9 Osteoarthrosis NOS Musculoskeletal 1.15 1.11 – 1.19 2.27e-17 4279 48128 exclusion phecode
741 Symptoms and disorders of the joints Musculoskeletal 1.11 1.05 – 1.17 0.000279 1391 13747 exclusion phecode
741.1 Ankylosis of joint Musculoskeletal 0.837 0.576 – 1.22 0.349 35 389 exclusion phecode
741.2 Stiffness of joint Musculoskeletal 1.09 0.959 – 1.25 0.182 253 2466 exclusion phecode
741.3 Difficulty in walking Musculoskeletal 1.04 0.79 – 1.37 0.78 59 562 exclusion phecode
741.4 Joint effusions Musculoskeletal 1.13 1.03 – 1.24 0.00753 560 5307 exclusion phecode
741.5 Hemarthrosis Musculoskeletal 0.974 0.688 – 1.38 0.884 35 417 exclusion phecode
741.6 Villonodular synovitis Musculoskeletal 0.933 0.593 – 1.47 0.765 20 233 exclusion phecode
742 Derangement of joint, non-traumatic Musculoskeletal 1.16 1.09 – 1.23 2.72e-06 1160 11432 exclusion phecode
742.1 Loose body in joint Musculoskeletal 1.18 0.978 – 1.42 0.0843 123 1240 exclusion phecode
742.2
Pathological, developmental or recurrent
Pathological, developmental or recurrent dislocation
 Musculoskeletal 1.24 0.915 – 1.69 0.164 47 391 exclusion phecode
742.8 Articular cartilage disorder Musculoskeletal 1.23 1.06 – 1.42 0.00606 208 1981 exclusion phecode
742.9 Other derangement of joint Musculoskeletal 1.14 1.06 – 1.23 0.000435 815 8075 exclusion phecode
743
Osteoporosis, osteopenia and pathological
Osteoporosis, osteopenia and pathological fracture
 Musculoskeletal 1.02 0.978 – 1.06 0.404 2902 30691 exclusion phecode
743.1 Osteoporosis Musculoskeletal 1 0.964 – 1.05 0.818 2459 26114 exclusion phecode
743.11 Osteoporosis NOS Musculoskeletal 1.01 0.964 – 1.05 0.721 2180 22971 exclusion phecode
743.13 Other specified osteoporosis Musculoskeletal 0.948 0.808 – 1.11 0.508 167 1943 exclusion phecode
743.2 Pathologic fracture Musculoskeletal 1.11 0.939 – 1.31 0.224 156 1992 exclusion phecode
743.9
Osteopenia or other disorder of bone and
Osteopenia or other disorder of bone and cartilage
 Musculoskeletal 1.09 0.969 – 1.22 0.156 337 3251 exclusion phecode
745 Pain in joint Musculoskeletal 1.15 1.11 – 1.19 6.07e-13 3060 31484 exclusion phecode
747 Cardiac and circulatory congenital anomalies Congenital Anomalies 1.05 0.976 – 1.12 0.199 908 10328 exclusion phecode
747.1 Cardiac congenital anomalies Congenital Anomalies 1.03 0.962 – 1.11 0.372 842 9660 exclusion phecode
747.11 Cardiac shunt/ heart septal defect Congenital Anomalies 1.1 0.958 – 1.26 0.181 238 2325 exclusion phecode
747.12 Valvular heart disease/ heart chambers Congenital Anomalies 0.949 0.757 – 1.19 0.652 81 869 exclusion phecode
747.13 Congenital anomalies of great vessels Congenital Anomalies 0.968 0.884 – 1.06 0.488 522 6446 exclusion phecode
747.2
Congenital anomalies of peripheral vascular
Congenital anomalies of peripheral vascular system
 Congenital Anomalies 1.09 0.85 – 1.4 0.496 66 625 exclusion phecode
748 Anomalies of respiratory system, congenital Congenital Anomalies 1.21 0.764 – 1.92 0.414 22 177 exclusion phecode
749 Congenital anomalies of face and neck Congenital Anomalies 0.943 0.774 – 1.15 0.561 110 1216 exclusion phecode
750 Digestive congenital anomalies Congenital Anomalies 0.9 0.788 – 1.03 0.12 254 2545 exclusion phecode
750.1 Upper gastrointestinal congenital anomalies Congenital Anomalies 0.94 0.773 – 1.14 0.535 114 1179 exclusion phecode
750.13 Congenital anomalies of mouth/tongue Congenital Anomalies 0.928 0.727 – 1.18 0.55 70 673 exclusion phecode
750.2 Lower gastrointestinal congenital anomalies Congenital Anomalies 0.853 0.714 – 1.02 0.0808 139 1384 exclusion phecode
750.21 Congenital anomalies of intestine Congenital Anomalies 0.882 0.703 – 1.11 0.275 83 871 exclusion phecode
750.22
Congenital anomaly of gallbladder, bile ducts
Congenital anomaly of gallbladder, bile ducts, liver, pancreas
 Congenital Anomalies 0.815 0.606 – 1.1 0.175 54 465 exclusion phecode
751 Genitourinary congenital anomalies Congenital Anomalies 1.05 0.961 – 1.14 0.288 587 6051 exclusion phecode
751.1 Congenital anomalies of genital organs Congenital Anomalies 1.11 0.981 – 1.25 0.0996 289 2881 exclusion phecode
751.11 Congenital anomalies of female genital organs Congenital Anomalies 1.14 0.992 – 1.32 0.0638 215 2025 exclusion phecode
751.12 Congenital anomalies of male genital organs Congenital Anomalies 1.02 0.782 – 1.33 0.885 62 741 exclusion phecode
751.2 Congenital anomalies of urinary system Congenital Anomalies 0.986 0.873 – 1.11 0.822 302 3186 exclusion phecode
751.21 Cystic kidney disease Congenital Anomalies 1.01 0.85 – 1.19 0.935 153 1605 exclusion phecode
751.22 Other specified congenital anomalies of kidney Congenital Anomalies 0.971 0.799 – 1.18 0.767 115 1281 exclusion phecode
752 Nervous system congenital anomalies Congenital Anomalies 1.14 0.954 – 1.36 0.151 141 1361 exclusion phecode
752.1 Neural tube defects Congenital Anomalies 1.1 0.9 – 1.34 0.354 110 1063 exclusion phecode
752.11 Spina bifida Congenital Anomalies 1.23 0.987 – 1.54 0.0646 86 873 exclusion phecode
752.2
Other specified congenital anomalies of nervous
Other specified congenital anomalies of nervous system
 Congenital Anomalies 1.02 0.701 – 1.47 0.933 33 326 exclusion phecode
753 Congenital anomalies of the eye Congenital Anomalies 1.14 0.852 – 1.53 0.374 54 511 exclusion phecode
753.1 Congenital cataract and lens anomalies Congenital Anomalies 1.07 0.717 – 1.58 0.754 33 309 exclusion phecode
754 Congenital musculoskeletal deformities of spine Congenital Anomalies 1.24 0.901 – 1.71 0.186 47 459 exclusion phecode
755 Congenital anomalies of limbs Congenital Anomalies 1.04 0.886 – 1.21 0.66 173 1730 exclusion phecode
755.1 Congenital deformities of feet Congenital Anomalies 0.985 0.78 – 1.24 0.9 77 838 exclusion phecode
755.6
Other congenital anomalies of lower limb
Other congenital anomalies of lower limb, including pelvic girdle
 Congenital Anomalies 1.11 0.858 – 1.43 0.429 69 687 exclusion phecode
755.61 Congenital hip dysplasia and deformity Congenital Anomalies 1.03 0.759 – 1.4 0.84 46 469 exclusion phecode
756 Other congenital musculoskeletal anomalies Congenital Anomalies 1.17 1.01 – 1.35 0.0325 211 2416 exclusion phecode
756.3
Congenital anomalies of muscle, tendon, fascia
Congenital anomalies of muscle, tendon, fascia, and connective tissue
 Congenital Anomalies 1.24 0.879 – 1.76 0.217 33 339 exclusion phecode
756.5 Congenital osteodystrophies Congenital Anomalies 1.22 1.02 – 1.44 0.0253 146 1804 exclusion phecode
758 Chromosomal anomalies and genetic disorders Congenital Anomalies 1.23 0.948 – 1.61 0.117 58 672 exclusion phecode
758.1 Chromosomal anomalies Congenital Anomalies 1.95 1.31 – 2.92 0.0011 23 353 exclusion phecode
759 Other and unspecified congenital anomalies Congenital Anomalies 0.992 0.788 – 1.25 0.945 81 871 exclusion phecode
759.1 Anomalies of endocrine glands, congenital Congenital Anomalies 0.939 0.64 – 1.38 0.748 29 372 exclusion phecode
760 Back pain Symptoms 1.11 1.07 – 1.14 1.73e-09 3906 44171 exclusion phecode
761 Cervicalgia Symptoms 1.13 1.04 – 1.23 0.00276 654 7129 exclusion phecode
764 Sciatica Symptoms 1.11 1.03 – 1.2 0.00586 788 9411 exclusion phecode
766 Neuralgia, neuritis, and radiculitis NOS Symptoms 1.13 1.02 – 1.25 0.02 413 4651 exclusion phecode
770 Myalgia and myositis unspecified Symptoms 0.966 0.848 – 1.1 0.599 259 2489 exclusion phecode
771 Musculoskeletal symptoms referable to limbs Symptoms 1.1 0.987 – 1.24 0.084 334 3411 exclusion phecode
771.1 Swelling of limb Symptoms 1.13 1.08 – 1.19 1.46e-06 1697 17920 exclusion phecode
772 Symptoms of the muscles Symptoms 0.998 0.874 – 1.14 0.981 240 2451 exclusion phecode
773 Pain in limb Symptoms 1.15 1.1 – 1.2 2.6e-10 2318 24753 exclusion phecode
780 Hypothermia/Chills Symptoms 1.06 0.802 – 1.4 0.691 57 612 exclusion phecode
781
Symptoms involving nervous and musculoskeletal
Symptoms involving nervous and musculoskeletal systems
 Symptoms 1.14 1.05 – 1.24 0.0015 655 7342 exclusion phecode
782.3 Edema Symptoms 1.1 1.01 – 1.2 0.031 555 6168 exclusion phecode
782.6 Pallor and flushing Symptoms 1.04 0.773 – 1.39 0.804 49 668 exclusion phecode
783 Fever of unknown origin Symptoms 1.01 0.958 – 1.07 0.65 1474 14920 exclusion phecode
785 Abdominal pain Symptoms 1.08 1.06 – 1.1 1.37e-18 15218 119213 exclusion phecode
788 Syncope and collapse Symptoms 1.04 1 – 1.08 0.043 3392 33887 exclusion phecode
789 Nausea and vomiting Symptoms 1.06 1.03 – 1.09 0.000423 4367 46345 exclusion phecode
790 Nonspecific findings on examination of blood Symptoms 0.749 0.567 – 0.991 0.0432 51 560 exclusion phecode
790.1 Elevated sedimentation rate Symptoms 1.12 0.78 – 1.62 0.533 30 297 exclusion phecode
790.6 Other abnormal blood chemistry Symptoms 1.07 1.02 – 1.12 0.00239 2172 21736 exclusion phecode
791 Gangrene Symptoms 0.975 0.837 – 1.14 0.746 182 2012 exclusion phecode
792
Abnormal Papanicolaou smear of cervix and
Abnormal Papanicolaou smear of cervix and cervical HPV
 Symptoms 1.1 0.74 – 1.64 0.634 24 388 exclusion phecode
793
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of musculoskeletal system
 Symptoms 1.26 0.913 – 1.74 0.16 38 505 exclusion phecode
793.2
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of other intrathoracic organs (echocardiogram, etc)
 Symptoms 1.07 0.924 – 1.24 0.361 192 2109 exclusion phecode
794
Abnormal results of other function studies
Abnormal results of other function studies (bladder, pancreas, placenta, spleen, etc)
 Symptoms 0.728 0.548 – 0.967 0.0282 50 531 exclusion phecode
797 Shock Symptoms 1.04 0.796 – 1.37 0.754 55 533 exclusion phecode
797.1 Cardiogenic shock Symptoms 1.08 0.783 – 1.49 0.643 38 346 exclusion phecode
798 Malaise and fatigue Symptoms 1.02 0.958 – 1.08 0.592 1293 13469 exclusion phecode
798.1 Chronic fatigue syndrome Symptoms 0.976 0.853 – 1.12 0.722 247 2477 exclusion phecode
800 Fracture of lower limb Injuries & Poisonings 1.08 1.04 – 1.13 0.000226 2553 28012 exclusion phecode
800.1 Fracture of neck of femur Injuries & Poisonings 1.02 0.94 – 1.11 0.629 636 7147 exclusion phecode
800.2 Fracture of unspecified part of femur Injuries & Poisonings 1.04 0.786 – 1.36 0.804 58 667 exclusion phecode
800.3 Fracture of tibia and fibula Injuries & Poisonings 1.11 1.03 – 1.2 0.00697 776 8454 exclusion phecode
800.4 Fracture of patella Injuries & Poisonings 1.03 0.908 – 1.16 0.671 271 2943 exclusion phecode
801 Fracture of ankle and foot Injuries & Poisonings 1.1 1.02 – 1.19 0.012 762 8691 exclusion phecode
801.1 Fracture of foot Injuries & Poisonings 1.07 0.988 – 1.16 0.0936 645 7213 exclusion phecode
802 Fracture of pelvis Injuries & Poisonings 1.26 1.1 – 1.43 0.000501 259 2686 exclusion phecode
803 Fracture of upper limb Injuries & Poisonings 1.03 0.998 – 1.07 0.0649 3337 33262 exclusion phecode
803.1 Fracture of humerus Injuries & Poisonings 1.01 0.931 – 1.1 0.815 652 6847 exclusion phecode
803.2 Fracture of radius and ulna Injuries & Poisonings 1.01 0.964 – 1.05 0.729 2200 21366 exclusion phecode
803.3 Fracture of clavicle or scapula Injuries & Poisonings 1.17 1.07 – 1.28 0.000785 534 5628 exclusion phecode
804 Fracture of hand or wrist Injuries & Poisonings 1.11 1.05 – 1.17 0.000551 1294 13060 exclusion phecode
805
Fracture of vertebral column without mention of
Fracture of vertebral column without mention of spinal cord injury
 Injuries & Poisonings 1.07 0.977 – 1.18 0.14 482 4949 exclusion phecode
807 Fracture of ribs Injuries & Poisonings 1.25 1.1 – 1.43 0.000744 252 2909 exclusion phecode
809 Fracture of unspecified bones Injuries & Poisonings 1.03 0.939 – 1.13 0.53 502 4854 exclusion phecode
817 Concussion Injuries & Poisonings 1.3 1.06 – 1.59 0.0118 103 910 exclusion phecode
818 Intracranial hemorrhage (injury) Injuries & Poisonings 0.966 0.828 – 1.13 0.653 174 1792 exclusion phecode
819
Skull and face fracture and other intercranial
Skull and face fracture and other intercranial injury
 Injuries & Poisonings 1.07 1.01 – 1.14 0.0285 1071 11468 exclusion phecode
823 Torus fracture Injuries & Poisonings 1.12 1.03 – 1.22 0.00926 589 6511 exclusion phecode
830 Dislocation Injuries & Poisonings 1.13 1.05 – 1.22 0.00151 790 8174 exclusion phecode
835 Internal derangement of knee Injuries & Poisonings 1.08 1.05 – 1.11 1.72e-08 5816 58512 exclusion phecode
836 Traumatic arthropathy Injuries & Poisonings 1.21 1.04 – 1.41 0.0159 185 2059 exclusion phecode
840 Sprains and strains Injuries & Poisonings 1.02 0.881 – 1.19 0.757 188 1820 exclusion phecode
850 Hemorrhage or hematoma complicating a procedure Injuries & Poisonings 1.01 0.965 – 1.06 0.616 1942 20246 exclusion phecode
851
Complications of transplants and reattached
Complications of transplants and reattached limbs
 Injuries & Poisonings 1.19 0.916 – 1.54 0.195 64 596 exclusion phecode
853 Complication of colostomy or enterostomy Injuries & Poisonings 1.03 0.881 – 1.21 0.684 165 1925 exclusion phecode
854
Complications of cardiac/vascular device
Complications of cardiac/vascular device, implant, and graft
 Injuries & Poisonings 1.13 1.03 – 1.24 0.0114 491 6457 exclusion phecode
857
Mechanical complication of unspecified
Mechanical complication of unspecified genitourinary device, implant, and graft
 Injuries & Poisonings 1.11 1.01 – 1.23 0.0352 432 4683 exclusion phecode
858 Complication of internal orthopedic device Injuries & Poisonings 1.12 1.05 – 1.19 0.000228 1189 12339 exclusion phecode
859
Complication due to other implant and internal
Complication due to other implant and internal device
 Injuries & Poisonings 1.14 1.07 – 1.21 3.1e-05 1209 12868 exclusion phecode
860 Bone marrow or stem cell transplant Neoplasms 0.834 0.571 – 1.22 0.347 31 257 exclusion phecode
870 Open wounds of head; neck; and trunk Injuries & Poisonings 1.14 1.07 – 1.21 4.77e-05 1174 13118 exclusion phecode
870.1 Open wound or laceration of eye or eyelid Injuries & Poisonings 1.09 0.878 – 1.34 0.448 93 1078 exclusion phecode
870.2 Open wound of ear Injuries & Poisonings 1.23 0.963 – 1.56 0.0975 74 730 exclusion phecode
870.3 Other open wound of head and face Injuries & Poisonings 1.14 1.06 – 1.21 0.00018 986 10830 exclusion phecode
870.4 Open wound of nose and sinus Injuries & Poisonings 1.01 0.79 – 1.3 0.924 74 817 exclusion phecode
870.6 Open wound of neck Injuries & Poisonings 1.31 0.843 – 2.04 0.23 20 252 exclusion phecode
871 Open wounds of extremities Injuries & Poisonings 1.13 1.07 – 1.2 1.94e-05 1327 15540 exclusion phecode
871.1 Open wound of hand except finger(s) Injuries & Poisonings 1.09 0.682 – 1.74 0.721 17 201 exclusion phecode
871.2 Open wound of finger(s) Injuries & Poisonings 1.01 0.675 – 1.51 0.969 28 303 exclusion phecode
871.3 Open wound of foot except toe(s) alone Injuries & Poisonings 1.37 1.04 – 1.82 0.0279 52 662 exclusion phecode
872 Traumatic amputation Injuries & Poisonings 1.07 0.898 – 1.28 0.446 146 1725 exclusion phecode
873 Broken tooth Injuries & Poisonings 1.03 0.834 – 1.27 0.783 94 909 exclusion phecode
874 Complication of amputation stump Injuries & Poisonings 1.64 1.19 – 2.25 0.00226 44 629 exclusion phecode
905
Late effects of musculoskeletal and connective
Late effects of musculoskeletal and connective tissue injuries
 Injuries & Poisonings 1.37 1.04 – 1.82 0.027 59 597 exclusion phecode
907 Injuries to the nervous system Injuries & Poisonings 1.14 1.03 – 1.26 0.0105 441 4971 exclusion phecode
915 Superficial injury without mention of infection Injuries & Poisonings 1.1 1.05 – 1.16 0.000338 1515 16443 exclusion phecode
916 Contusion Injuries & Poisonings 1.11 1.02 – 1.21 0.0181 544 5641 exclusion phecode
930 Allergic reaction to food Injuries & Poisonings 0.851 0.649 – 1.12 0.245 56 764 exclusion phecode
938 Dermatitis due to solar radiation Injuries & Poisonings 0.903 0.758 – 1.08 0.253 143 1383 exclusion phecode
938.2 Chronic dermatitis due to solar radiation Injuries & Poisonings 0.817 0.661 – 1.01 0.0636 96 889 exclusion phecode
939
Atopic/contact dermatitis due to other or
Atopic/contact dermatitis due to other or unspecified
 Dermatologic 0.965 0.896 – 1.04 0.351 777 8217 exclusion phecode
941 Adverse reaction to serum or vaccine Injuries & Poisonings 0.865 0.671 – 1.12 0.266 67 889 exclusion phecode
942 Infusion and transfusion reaction Injuries & Poisonings 0.885 0.66 – 1.19 0.411 52 405 exclusion phecode
946 Anaphylactic shock NOS Injuries & Poisonings 1.04 0.883 – 1.23 0.621 160 2137 exclusion phecode
947 Urticaria Injuries & Poisonings 1.06 0.888 – 1.26 0.531 141 1445 exclusion phecode
949 Allergies, other Injuries & Poisonings 1.17 0.986 – 1.38 0.073 155 1617 exclusion phecode
952
Spinal cord injury without evidence of spinal
Spinal cord injury without evidence of spinal bone injury
 Injuries & Poisonings 1.21 1.02 – 1.43 0.0293 154 1528 exclusion phecode
957 Injury to other and unspecified nerves Injuries & Poisonings 1.06 0.84 – 1.34 0.626 81 988 exclusion phecode
958
Certain early complications of trauma or
Certain early complications of trauma or procedure
 Injuries & Poisonings 1.16 0.995 – 1.36 0.0582 176 1899 exclusion phecode
958.1 Postoperative shock Injuries & Poisonings 1.14 0.732 – 1.77 0.563 21 212 exclusion phecode
958.2 Traumatic and surgical subcutaneous emphysema Injuries & Poisonings 1 0.674 – 1.48 0.999 25 259 exclusion phecode
960 Poisoning by antibiotics Injuries & Poisonings 1.07 1.04 – 1.09 7.51e-07 6836 73675 exclusion phecode
960.2 Allergy/adverse effect of penicillin Injuries & Poisonings 1.07 1.04 – 1.1 3.14e-06 5921 64182 exclusion phecode
961 Poisoning by other anti-infectives Injuries & Poisonings 0.97 0.81 – 1.16 0.743 132 1720 exclusion phecode
961.1 Poisoning/allergy of sulfonamides Injuries & Poisonings 0.983 0.881 – 1.1 0.76 369 3752 exclusion phecode
962 Poisoning by hormones and synthetic substitutes Injuries & Poisonings 1.14 0.947 – 1.38 0.164 124 1441 exclusion phecode
962.3
Hormones and synthetic substitutes causing
Hormones and synthetic substitutes causing adverse effects in therapeutic use
 Injuries & Poisonings 1.18 0.972 – 1.43 0.094 117 1422 exclusion phecode
963 Poisoning by primarily systemic agents Injuries & Poisonings 1.17 0.924 – 1.49 0.19 74 980 exclusion phecode
964
Poisoning by agents primarily affecting blood
Poisoning by agents primarily affecting blood constituents
 Injuries & Poisonings 1.12 0.905 – 1.38 0.299 95 1108 exclusion phecode
964.1 Anticoagulants causing adverse effects Injuries & Poisonings 1.12 0.906 – 1.39 0.292 93 1084 exclusion phecode
965
Poisoning by analgesics, antipyretics, and
Poisoning by analgesics, antipyretics, and antirheumatics
 Injuries & Poisonings 1.11 1.06 – 1.16 1.59e-05 2102 24800 exclusion phecode
965.1
Opiates and related narcotics causing adverse
Opiates and related narcotics causing adverse effects in therapeutic use
 Injuries & Poisonings 1.07 0.969 – 1.18 0.181 438 4788 exclusion phecode
965.2
Antirheumatics causing adverse effects in
Antirheumatics causing adverse effects in therapeutic use
 Injuries & Poisonings 1.25 1.05 – 1.49 0.0138 136 2061 exclusion phecode
965.3
Salicylates causing adverse effects in
Salicylates causing adverse effects in therapeutic use
 Injuries & Poisonings 1.37 1.12 – 1.69 0.0028 95 1590 exclusion phecode
966
Poisoning by anticonvulsants and
Poisoning by anticonvulsants and anti-Parkinsonism drugs
 Injuries & Poisonings 1.17 0.999 – 1.38 0.0509 169 2120 exclusion phecode
967
Adverse effects of sedatives or other central
Adverse effects of sedatives or other central nervous system depressants and anesthetics
 Injuries & Poisonings 1.17 1.02 – 1.35 0.0248 224 2363 exclusion phecode
969 Poisoning by psychotropic agents Injuries & Poisonings 1.19 1.09 – 1.3 0.000161 535 8176 exclusion phecode
971
Poisoning by drugs primarily affecting the
Poisoning by drugs primarily affecting the autonomic nervous system
 Injuries & Poisonings 1.42 1.07 – 1.89 0.0163 56 735 exclusion phecode
972
Poisoning by agents primarily affecting the
Poisoning by agents primarily affecting the cardiovascular system
 Injuries & Poisonings 1.51 1.18 – 1.94 0.00107 73 1065 exclusion phecode
972.6 Antihypertensive agents causing adverse effects Injuries & Poisonings 2.03 1.3 – 3.18 0.00196 26 329 exclusion phecode
973
Poisoning by agents primarily affecting the
Poisoning by agents primarily affecting the gastrointestinal system
 Injuries & Poisonings 1.74 1.17 – 2.58 0.00639 33 433 exclusion phecode
974
Poisoning by water, mineral, and uric acid
Poisoning by water, mineral, and uric acid metabolism drugs
 Injuries & Poisonings 1.26 0.862 – 1.84 0.234 25 372 exclusion phecode
975
Poisoning by agents primarily acting on the
Poisoning by agents primarily acting on the smooth and skeletal muscles and respiratory system
 Injuries & Poisonings 1.21 0.766 – 1.92 0.409 17 251 exclusion phecode
976
Poisoning by agents primarily affecting skin &
Poisoning by agents primarily affecting skin & mucous membrane, ophthalmological, otorhinolaryngological, & dental drugs
 Injuries & Poisonings 0.992 0.617 – 1.59 0.974 19 257 exclusion phecode
977 Personal history of allergy to medicinal agents Injuries & Poisonings 1.2 0.961 – 1.49 0.109 91 978 exclusion phecode
979 Adverse drug events and drug allergies Injuries & Poisonings 1.15 1 – 1.33 0.0461 214 2937 exclusion phecode
981
Toxic effect of (non-ethyl) alcohol and
Toxic effect of (non-ethyl) alcohol and petroleum and other solvents
 Injuries & Poisonings 1.31 0.984 – 1.74 0.0646 52 839 exclusion phecode
986 Toxic effect of carbon monoxide Injuries & Poisonings 1.8 1.09 – 2.96 0.0219 22 252 exclusion phecode
987 Toxic effect of other gases, fumes, or vapors Injuries & Poisonings 1.07 0.686 – 1.67 0.765 22 407 exclusion phecode
988 Toxic effect of noxious substances eaten as food Injuries & Poisonings 0.844 0.606 – 1.18 0.318 38 457 exclusion phecode
989
Toxic effect of other substances, chiefly
Toxic effect of other substances, chiefly nonmedicinal as to source
 Injuries & Poisonings 1.03 0.688 – 1.53 0.899 25 337 exclusion phecode
990 Effects radiation NOS Injuries & Poisonings 1.07 0.999 – 1.14 0.0526 974 11919 exclusion phecode
994 Sepsis and SIRS Injuries & Poisonings 1 0.941 – 1.07 0.9 1016 11360 exclusion phecode
994.2 Sepsis Injuries & Poisonings 1 0.941 – 1.07 0.9 1016 11360 exclusion phecode
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