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Scores Smoking initiation UK Biobank (UKB) PheWAS analysis

Smoking initiation — UK Biobank (UKB) PRS PheWAS

PRS model
PRS ID exprsweb-smoker-yes-smokinginitiation-plink-ukb-20211120Legacy PLINKC+T (GT)Large GWAS

Evaluation cohort: UK Biobank (UKB).

This page pairs the PheWAS plot with the full sortable table for the all-subject and exclusion scans.

Read the all-subject and exclusion scans separately. The combined view is only a browsing aid, and the selected-phecode panel below is only meaningful when the same phecode exists in both scans.

ExPRS exclusion definition

Exclusion cohort: individuals without Smoking initiation.

For this ExPRS, the exclusion sensitivity scan removes individuals with the exposure itself before rerunning the PheWAS. This is an exposure-based sensitivity analysis rather than a diagnosis-based exclusion.

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Signal overview

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797 rows visible 17 categories
Phecode Description Category OR 95% CI P value Cases Controls Analysis Link
008 Intestinal infection Infectious Diseases 1.12 1.1 – 1.15 7.7e-25 8842 88430 all phecode
008.5 Bacterial enteritis Infectious Diseases 1.14 1.1 – 1.19 6.91e-11 2718 27172 all phecode
008.52 Intestinal infection due to C. difficile Infectious Diseases 1.09 1.01 – 1.18 0.0359 653 6533 all phecode
008.6 Viral Enteritis Infectious Diseases 1.16 1.08 – 1.25 3.84e-05 862 8622 all phecode
008.7 Intestinal infection due to protozoa Infectious Diseases 0.964 0.737 – 1.26 0.786 55 550 all phecode
010 Tuberculosis Infectious Diseases 1.14 0.977 – 1.34 0.0953 166 1659 all phecode
038 Septicemia Infectious Diseases 1.12 1.08 – 1.15 1.71e-11 4175 41776 all phecode
038.1 Gram negative septicemia Infectious Diseases 1.08 1 – 1.16 0.0393 850 8501 all phecode
038.2 Gram positive septicemia Infectious Diseases 1.17 1.07 – 1.29 0.000952 494 4978 all phecode
041 Bacterial infection NOS Infectious Diseases 1.14 1.12 – 1.17 1.13e-43 12017 120377 all phecode
041.1 Staphylococcus infections Infectious Diseases 1.17 1.12 – 1.21 3.19e-16 3128 31348 all phecode
041.2 Streptococcus infection Infectious Diseases 1.15 1.09 – 1.21 1.95e-07 1641 16433 all phecode
041.4 E. coli Infectious Diseases 1.15 1.11 – 1.2 1.86e-12 2730 27319 all phecode
053 Herpes zoster Infectious Diseases 1.14 1.02 – 1.26 0.0152 411 4137 all phecode
053.1 Herpes zoster with nervous system complications Infectious Diseases 1.19 0.96 – 1.47 0.113 95 949 all phecode
054 Herpes simplex Infectious Diseases 1.04 0.9 – 1.2 0.594 211 2107 all phecode
070 Viral hepatitis Infectious Diseases 1.39 1.28 – 1.52 4.86e-14 590 5916 all phecode
070.1 Viral hepatitis A Infectious Diseases 1.35 1.05 – 1.74 0.0212 69 690 all phecode
070.2 Viral hepatitis B Infectious Diseases 1.46 1.21 – 1.76 7.55e-05 132 1330 all phecode
070.3 Viral hepatitis C Infectious Diseases 1.72 1.5 – 1.96 4.22e-15 255 2568 all phecode
070.4 Chronic hepatitis Infectious Diseases 1.1 0.962 – 1.25 0.168 276 2767 all phecode
070.9 Hepatitis NOS Infectious Diseases 1.15 1.04 – 1.27 0.00849 428 4287 all phecode
071 Human immunodeficiency virus [HIV] disease Infectious Diseases 1.12 0.941 – 1.33 0.205 147 1467 all phecode
071.1 HIV infection, symptomatic Infectious Diseases 1.11 0.918 – 1.35 0.273 117 1168 all phecode
078 Viral warts & HPV Infectious Diseases 1.04 0.972 – 1.11 0.274 1004 10036 all phecode
079 Viral infection Infectious Diseases 1.07 1.03 – 1.11 0.00075 2769 27694 all phecode
079.1 Varicella infection Infectious Diseases 1.06 0.818 – 1.38 0.648 64 640 all phecode
080 Postoperative infection Infectious Diseases 1.17 1.14 – 1.21 2.83e-23 4473 44775 all phecode
081
Infection/inflammation of internal prosthetic
Infection/inflammation of internal prosthetic device; implant; and graft
 Infectious Diseases 1.18 1.13 – 1.23 1.75e-14 2477 24765 all phecode
090
Sexually transmitted infections (not HIV or
Sexually transmitted infections (not HIV or hepatitis)
 Infectious Diseases 1.11 0.869 – 1.41 0.416 71 709 all phecode
1000 Burns Injuries & Poisonings 1.07 0.977 – 1.16 0.15 578 5796 all phecode
1001 Foreign body injury Injuries & Poisonings 1.09 1.03 – 1.16 0.00425 1199 12007 all phecode
1002
Symptoms concerning nutrition, metabolism, and
Symptoms concerning nutrition, metabolism, and development
 Injuries & Poisonings 1.09 1.06 – 1.12 7.65e-09 5480 54819 all phecode
1004
Other signs and symptoms involving emotional
Other signs and symptoms involving emotional state
 Injuries & Poisonings 1.24 1.1 – 1.4 0.000396 300 2997 all phecode
1005 Other symptoms Injuries & Poisonings 1.16 1.1 – 1.23 9.07e-08 1444 14422 all phecode
1006 Crushing injury Injuries & Poisonings 1.15 1.01 – 1.31 0.0369 256 2558 all phecode
1007 Injury to blood vessels Injuries & Poisonings 1.23 1.08 – 1.4 0.00223 256 2559 all phecode
1008 Crushing or internal injury to organs Injuries & Poisonings 1.14 1.07 – 1.22 7.69e-05 1013 10132 all phecode
1009 Injury, NOS Injuries & Poisonings 1.09 1.06 – 1.11 1.45e-13 8482 84911 all phecode
1010 Other tests Injuries & Poisonings 1.1 1.07 – 1.13 1.03e-12 5945 59512 all phecode
1011 Complications of surgical and medical procedures Injuries & Poisonings 1.13 1.11 – 1.15 6.04e-28 9152 91588 all phecode
1012 Late effect Injuries & Poisonings 0.999 0.814 – 1.23 0.991 105 1057 all phecode
1013 Asphyxia and hypoxemia Injuries & Poisonings 1.17 1.04 – 1.31 0.00936 316 3168 all phecode
1014 Effects of heat, cold and air pressure Injuries & Poisonings 0.947 0.744 – 1.21 0.658 66 659 all phecode
1015 Effects of other external causes Injuries & Poisonings 1.19 1.16 – 1.23 2.34e-27 4226 42294 all phecode
1019
Other ill-defined and unknown causes of
Other ill-defined and unknown causes of morbidity and mortality
 Injuries & Poisonings 1.09 1.07 – 1.11 2.92e-24 15895 159019 all phecode
110 Dermatophytosis / Dermatomycosis Infectious Diseases 1.04 0.916 – 1.17 0.574 279 2810 all phecode
110.1 Dermatophytosis Infectious Diseases 1 0.883 – 1.13 0.993 273 2750 all phecode
110.11 Dermatophytosis of nail Infectious Diseases 0.919 0.725 – 1.17 0.489 74 756 all phecode
110.12 Althete's foot Infectious Diseases 1.05 0.886 – 1.25 0.561 141 1410 all phecode
112 Candidiasis Infectious Diseases 1.2 1.15 – 1.25 5.23e-15 2126 21275 all phecode
117 Mycoses Infectious Diseases 1.1 0.97 – 1.24 0.137 272 2719 all phecode
117.4 Aspergillosis Infectious Diseases 1.04 0.888 – 1.22 0.62 165 1650 all phecode
130 Spirochetal infection Infectious Diseases 0.942 0.75 – 1.18 0.607 80 800 all phecode
133 Arthropod-borne diseases Infectious Diseases 0.979 0.764 – 1.26 0.868 69 689 all phecode
134 Helminthiases Infectious Diseases 1.12 0.925 – 1.37 0.239 127 1267 all phecode
134.1 Intestinal helminthiases Infectious Diseases 1.09 0.884 – 1.34 0.419 106 1058 all phecode
136 Other infectious and parasitic diseases Infectious Diseases 0.919 0.796 – 1.06 0.251 205 2050 all phecode
145 Cancer of mouth Neoplasms 1.18 1.09 – 1.29 6.42e-05 642 6415 all phecode
145.2 Cancer of tongue Neoplasms 1.21 1.07 – 1.36 0.00224 310 3096 all phecode
145.3 Cancer of major salivary glands Neoplasms 0.957 0.788 – 1.16 0.659 105 1049 all phecode
145.5 Cancer of the mouth floor Neoplasms 1.5 1.13 – 1.99 0.00548 54 539 all phecode
149 Cancer of larynx, pharynx, nasal cavities Neoplasms 1.33 1.23 – 1.45 1.19e-11 635 6342 all phecode
149.1 Cancer of oropharynx Neoplasms 1.22 1.07 – 1.39 0.00297 252 2517 all phecode
149.4 Cancer of larynx Neoplasms 1.59 1.39 – 1.81 4.89e-12 265 2640 all phecode
149.9 Cancer of of nasal cavities Neoplasms 0.93 0.714 – 1.21 0.589 57 570 all phecode
150 Cancer of esophagus Neoplasms 1.31 1.22 – 1.42 2.64e-12 762 7630 all phecode
151 Cancer of stomach Neoplasms 1.23 1.13 – 1.34 2.93e-06 569 5696 all phecode
153 Colorectal cancer Neoplasms 1.07 1.03 – 1.1 3.73e-05 4580 45799 all phecode
153.2 Colon cancer Neoplasms 1.06 1.02 – 1.1 0.00289 3105 31046 all phecode
153.3
Malignant neoplasm of rectum, rectosigmoid
Malignant neoplasm of rectum, rectosigmoid junction, and anus
 Neoplasms 1.09 1.05 – 1.14 6.12e-05 2164 21640 all phecode
155 Cancer of liver and intrahepatic bile duct Neoplasms 1.16 1.05 – 1.29 0.00402 400 4008 all phecode
155.1 Malignant neoplasm of liver, primary Neoplasms 1.21 1.03 – 1.42 0.0239 158 1580 all phecode
157 Pancreatic cancer Neoplasms 1.17 1.08 – 1.26 0.000143 659 6582 all phecode
158
Neoplasm of unspecified nature of digestive
Neoplasm of unspecified nature of digestive system
 Neoplasms 1.06 0.996 – 1.13 0.0656 1063 10635 all phecode
159
Malignant neoplasm of other and ill-defined
Malignant neoplasm of other and ill-defined sites within the digestive organs and peritoneum
 Neoplasms 1.09 1.06 – 1.12 5.27e-10 5567 55694 all phecode
159.2
Malignant neoplasm of small intestine
Malignant neoplasm of small intestine, including duodenum
 Neoplasms 1.02 0.88 – 1.19 0.761 190 1900 all phecode
159.3
Malignant neoplasm of gallbladder and
Malignant neoplasm of gallbladder and extrahepatic bile ducts
 Neoplasms 1.14 0.988 – 1.32 0.072 205 2048 all phecode
159.4
Malignant neoplasm of retroperitoneum and
Malignant neoplasm of retroperitoneum and peritoneum
 Neoplasms 1.09 0.934 – 1.26 0.284 193 1925 all phecode
164 Cancer of intrathoracic organs Neoplasms 0.929 0.712 – 1.21 0.587 60 600 all phecode
165 Cancer within the respiratory system Neoplasms 1.52 1.46 – 1.58 1.3e-92 2824 28235 all phecode
165.1 Cancer of bronchus; lung Neoplasms 1.57 1.5 – 1.64 7.72e-83 2230 22307 all phecode
170 Cancer of bone and connective tissue Neoplasms 1.08 0.975 – 1.19 0.146 437 4364 all phecode
170.1 Bone cancer Neoplasms 1.11 0.924 – 1.33 0.266 131 1309 all phecode
170.2 Cancer of connective tissue Neoplasms 1.11 0.991 – 1.25 0.0718 331 3303 all phecode
172 Skin cancer Neoplasms 0.967 0.95 – 0.984 0.000194 13495 134987 all phecode
172.1 Melanomas of skin, dx or hx Neoplasms 0.938 0.901 – 0.977 0.00185 2681 26792 all phecode
172.11 Melanomas of skin Neoplasms 0.94 0.903 – 0.978 0.00236 2713 27112 all phecode
172.2 Other non-epithelial cancer of skin Neoplasms 0.971 0.952 – 0.991 0.0037 11000 110056 all phecode
172.3 Carcinoma in situ of skin Neoplasms 0.989 0.912 – 1.07 0.79 666 6656 all phecode
173 Neoplasm of uncertain behavior of skin Neoplasms 0.921 0.793 – 1.07 0.28 181 1818 all phecode
174 Breast cancer Neoplasms 1.02 0.998 – 1.04 0.0736 12686 126597 all phecode
174.1 Breast cancer [female] Neoplasms 1.02 0.999 – 1.04 0.0627 12476 124506 all phecode
174.11 Malignant neoplasm of female breast Neoplasms 1.02 1 – 1.04 0.0444 11757 117502 all phecode
174.3 Neoplasm of uncertain behavior of breast Neoplasms 0.825 0.678 – 1.01 0.0563 115 1148 all phecode
175 Acquired absence of breast Neoplasms 1.07 1.02 – 1.11 0.00444 2400 24010 all phecode
180 Cervical cancer and dysplasia Neoplasms 1.14 1.09 – 1.19 9.08e-09 2174 21747 all phecode
180.1 Cervical cancer Neoplasms 1.15 1.01 – 1.31 0.0284 272 2720 all phecode
180.3
Cervical intraepithelial neoplasia [CIN]
Cervical intraepithelial neoplasia [CIN] [Cervical dysplasia]
 Neoplasms 1.14 1.09 – 1.2 1.01e-08 2078 20784 all phecode
182 Malignant neoplasm of uterus Neoplasms 0.956 0.9 – 1.02 0.149 1282 12836 all phecode
184 Cancer of other female genital organs Neoplasms 1.05 0.987 – 1.11 0.132 1378 13772 all phecode
184.1
Malignant neoplasm of ovary and other uterine
Malignant neoplasm of ovary and other uterine adnexa
 Neoplasms 1.01 0.942 – 1.08 0.782 967 9667 all phecode
184.11 Malignant neoplasm of ovary Neoplasms 1 0.935 – 1.08 0.93 939 9387 all phecode
184.2
Cancer of other female genital organs
Cancer of other female genital organs (excluding uterus and ovary)
 Neoplasms 1.13 1 – 1.28 0.043 305 3049 all phecode
185 Cancer of prostate Neoplasms 0.96 0.935 – 0.985 0.00177 5974 58812 all phecode
187 Cancer of other male genital organs Neoplasms 1.02 0.923 – 1.12 0.736 449 4485 all phecode
187.1
Malignant neoplasm of unspecified male genital
Malignant neoplasm of unspecified male genital organ
 Neoplasms 1.01 0.796 – 1.28 0.927 70 700 all phecode
187.2 Malignant neoplasm of testis Neoplasms 1.03 0.915 – 1.17 0.589 287 2868 all phecode
187.8
Neoplasm of uncertain behavior of male genital
Neoplasm of uncertain behavior of male genital organs
 Neoplasms 0.991 0.819 – 1.2 0.925 110 1098 all phecode
189
Cancer of urinary organs (incl. kidney and
Cancer of urinary organs (incl. kidney and bladder)
 Neoplasms 1.14 1.1 – 1.18 7.16e-16 4160 41604 all phecode
189.1 Cancer of kidney and renal pelvis Neoplasms 1.1 1.03 – 1.17 0.00359 1073 10723 all phecode
189.11 Malignant neoplasm of kidney, except pelvis Neoplasms 1.1 1.03 – 1.17 0.0032 1033 10324 all phecode
189.12 Malignant neoplasm of renal pelvis Neoplasms 0.999 0.779 – 1.28 0.993 66 660 all phecode
189.2 Cancer of bladder Neoplasms 1.2 1.15 – 1.25 4.1e-17 2409 24113 all phecode
189.21 Malignant neoplasm of bladder Neoplasms 1.23 1.17 – 1.28 2.2e-19 2142 21447 all phecode
189.4 Malignant neoplasm of other urinary organs Neoplasms 1.06 0.891 – 1.26 0.52 144 1439 all phecode
190 Cancer of eye Neoplasms 0.915 0.783 – 1.07 0.265 176 1758 all phecode
191
Manlignant and unknown neoplasms of brain and
Manlignant and unknown neoplasms of brain and nervous system
 Neoplasms 1.03 0.956 – 1.12 0.398 689 6879 all phecode
191.1 Cancer of brain and nervous system Neoplasms 1.04 0.953 – 1.13 0.392 566 5650 all phecode
191.11 Cancer of brain Neoplasms 1.06 0.974 – 1.16 0.169 525 5240 all phecode
193 Thyroid cancer Neoplasms 1.03 0.919 – 1.15 0.628 346 3466 all phecode
194 Cancer of other endocrine glands Neoplasms 1.23 1 – 1.52 0.0484 95 949 all phecode
195 Cancer, suspected or other Neoplasms 1.07 1.05 – 1.09 3.05e-17 16967 165463 all phecode
195.1 Malignant neoplasm, other Neoplasms 1.07 1.06 – 1.09 1.15e-17 16267 159497 all phecode
197 Chemotherapy Neoplasms 1.11 1.09 – 1.12 1.02e-45 21433 213213 all phecode
198 Secondary malignant neoplasm Neoplasms 1.13 1.1 – 1.15 7.57e-28 9552 95503 all phecode
198.1 Secondary malignancy of lymph nodes Neoplasms 1.09 1.06 – 1.12 2.58e-09 5368 53670 all phecode
198.2 Secondary malignancy of respiratory organs Neoplasms 1.15 1.1 – 1.21 1.32e-10 2267 22670 all phecode
198.3
Secondary malignant neoplasm of digestive
Secondary malignant neoplasm of digestive systems
 Neoplasms 1.06 1 – 1.12 0.0382 1549 15496 all phecode
198.4 Secondary malignant neoplasm of liver Neoplasms 1.13 1.09 – 1.18 2.35e-09 2665 26648 all phecode
198.5 Secondary malignancy of brain/spine Neoplasms 1.22 1.13 – 1.31 8.63e-08 848 8473 all phecode
198.6 Secondary malignancy of bone Neoplasms 1.17 1.12 – 1.23 2.94e-12 2161 21600 all phecode
198.7 Secondary malignant neoplasm of skin Neoplasms 0.97 0.834 – 1.13 0.698 188 1890 all phecode
199 Neoplasm of uncertain behavior Neoplasms 1.13 1.07 – 1.2 8.76e-06 1432 14313 all phecode
199.4 Neurofibromatosis Neoplasms 0.929 0.759 – 1.14 0.478 95 950 all phecode
200 Myeloproliferative disease Neoplasms 1.07 1 – 1.14 0.0511 991 9911 all phecode
200.1 Polycythemia vera Neoplasms 1.12 1.01 – 1.24 0.0351 387 3867 all phecode
201 Hodgkin's disease Neoplasms 0.966 0.851 – 1.1 0.592 259 2598 all phecode
202 Cancer of other lymphoid, histiocytic tissue Neoplasms 1.01 0.964 – 1.05 0.768 2264 22709 all phecode
202.2 Non-Hodgkins lymphoma Neoplasms 0.999 0.951 – 1.05 0.96 1802 18073 all phecode
202.21 Nodular lymphoma Neoplasms 1.01 0.908 – 1.13 0.833 363 3647 all phecode
202.24 Large cell lymphoma Neoplasms 0.957 0.878 – 1.04 0.313 581 5824 all phecode
204 Leukemia Neoplasms 1.03 0.983 – 1.09 0.2 1660 16630 all phecode
204.1 Lymphoid leukemia Neoplasms 1.1 1.01 – 1.2 0.0305 577 5784 all phecode
204.11 Lymphoid leukemia, acute Neoplasms 1.17 0.881 – 1.55 0.281 56 560 all phecode
204.12 Lymphoid leukemia, chronic Neoplasms 1.07 0.98 – 1.18 0.129 507 5084 all phecode
204.2 Myeloid leukemia Neoplasms 0.988 0.898 – 1.09 0.809 462 4617 all phecode
204.21 Myeloid leukemia, acute Neoplasms 1.02 0.907 – 1.14 0.786 329 3287 all phecode
204.22 Myeloid leukemia, chronic Neoplasms 0.96 0.809 – 1.14 0.639 144 1440 all phecode
204.4 Multiple myeloma Neoplasms 1.03 0.943 – 1.12 0.523 555 5560 all phecode
208 Benign neoplasm of colon Neoplasms 1.14 1.12 – 1.16 9.14e-68 19856 191891 all phecode
210 Benign neoplasm of lip, oral cavity, and pharynx Neoplasms 1.07 1 – 1.14 0.0517 978 9781 all phecode
211
Benign neoplasm of other parts of digestive
Benign neoplasm of other parts of digestive system
 Neoplasms 0.964 0.937 – 0.993 0.0136 5243 52452 all phecode
212
Benign neoplasm of respiratory and
Benign neoplasm of respiratory and intrathoracic organs
 Neoplasms 1.19 1.06 – 1.33 0.00229 347 3466 all phecode
213 Benign neoplasm of bone and articular cartilage Neoplasms 1.02 0.913 – 1.15 0.677 318 3187 all phecode
214 Lipoma Neoplasms 1.1 1.07 – 1.12 1.19e-11 6231 62346 all phecode
214.1 Lipoma of skin and subcutaneous tissue Neoplasms 1.11 1.07 – 1.14 1.4e-10 4585 45872 all phecode
215
Other benign neoplasm of connective and other
Other benign neoplasm of connective and other soft tissue
 Neoplasms 1.07 1.01 – 1.14 0.0326 1107 11061 all phecode
216 Benign neoplasm of skin Neoplasms 1 0.981 – 1.03 0.684 7664 76660 all phecode
217 Vascular hamartomas and non-neoplastic nevi Neoplasms 1.11 1.03 – 1.21 0.00982 632 6313 all phecode
217.1 Nevus, non-neoplastic Neoplasms 1.09 1.01 – 1.19 0.038 595 5943 all phecode
218 Benign neoplasm of uterus Neoplasms 0.986 0.965 – 1.01 0.188 10023 100200 all phecode
218.1 Uterine leiomyoma Neoplasms 0.981 0.961 – 1 0.0779 10241 102376 all phecode
218.2 Other benign neoplasm of uterus Neoplasms 1.04 0.928 – 1.16 0.506 355 3548 all phecode
220 Benign neoplasm of ovary Neoplasms 1.05 0.991 – 1.11 0.1 1445 14483 all phecode
221 Benign neoplasm of other female genital organs Neoplasms 1.1 0.961 – 1.27 0.161 220 2196 all phecode
222 Benign neoplasm of male genital organs Neoplasms 0.897 0.759 – 1.06 0.203 160 1600 all phecode
223
Benign neoplasm of kidney and other urinary
Benign neoplasm of kidney and other urinary organs
 Neoplasms 1.21 1.04 – 1.42 0.0132 173 1729 all phecode
224 Benign neoplasm of eye Neoplasms 1.1 0.916 – 1.33 0.299 129 1299 all phecode
224.1 Benign neoplasm of eye, uveal Neoplasms 1.1 0.843 – 1.43 0.492 67 680 all phecode
225
Benign neoplasm of brain and other parts of
Benign neoplasm of brain and other parts of nervous system
 Neoplasms 0.992 0.922 – 1.07 0.822 816 8155 all phecode
225.1
Benign neoplasm of brain, cranial nerves
Benign neoplasm of brain, cranial nerves, meninges
 Neoplasms 0.975 0.904 – 1.05 0.505 775 7756 all phecode
225.2 Benign neoplasm of spinal cord, meninges Neoplasms 1.28 0.97 – 1.68 0.0817 59 589 all phecode
226 Benign neoplasm of thyroid glands Neoplasms 0.911 0.802 – 1.04 0.155 266 2664 all phecode
227
Benign neoplasm of other endocrine glands and
Benign neoplasm of other endocrine glands and related structures
 Neoplasms 1.08 1.01 – 1.16 0.0324 861 8635 all phecode
227.1 Benign neoplasm of adrenal gland Neoplasms 1.32 1.13 – 1.54 0.000393 186 1857 all phecode
227.2 Benign neoplasm of parathyroid gland Neoplasms 1.06 0.951 – 1.18 0.291 371 3709 all phecode
227.3
Benign neoplasm of pituitary gland and
Benign neoplasm of pituitary gland and craniopharyngeal duct (pouch)
 Neoplasms 1.01 0.894 – 1.13 0.925 309 3114 all phecode
228 Hemangioma and lymphangioma, any site Neoplasms 1.01 0.959 – 1.06 0.696 1596 15966 all phecode
229 Benign neoplasm of unspecified sites Neoplasms 0.984 0.942 – 1.03 0.451 2397 23955 all phecode
240 Simple and unspecified goiter Endocrine/metabolic 1.06 0.97 – 1.15 0.203 600 6016 all phecode
241 Nontoxic nodular goiter Endocrine/metabolic 1.02 0.955 – 1.08 0.607 1107 11092 all phecode
241.1 Nontoxic uninodular goiter Endocrine/metabolic 1.01 0.919 – 1.11 0.819 471 4706 all phecode
241.2 Nontoxic multinodular goiter Endocrine/metabolic 1.02 0.94 – 1.11 0.639 676 6784 all phecode
242 Thyrotoxicosis with or without goiter Endocrine/metabolic 1.09 1.04 – 1.14 0.000609 1854 18531 all phecode
242.1 Graves' disease Endocrine/metabolic 1.15 1.04 – 1.26 0.00641 456 4553 all phecode
242.2 Toxic multinodular goiter Endocrine/metabolic 1.07 0.855 – 1.33 0.572 91 910 all phecode
242.3 Exophthalmos Endocrine/metabolic 1.18 0.994 – 1.41 0.0591 138 1379 all phecode
244 Hypothyroidism Endocrine/metabolic 1.1 1.08 – 1.12 1.33e-27 14590 145053 all phecode
244.1 Secondary hypothyroidism Endocrine/metabolic 1.13 1.06 – 1.21 0.000105 1108 11079 all phecode
244.2 Acquired hypothyroidism Endocrine/metabolic 1.01 0.825 – 1.25 0.891 101 1010 all phecode
244.4 Hypothyroidism NOS Endocrine/metabolic 1.1 1.08 – 1.12 1.4e-26 13918 138926 all phecode
245 Thyroiditis Endocrine/metabolic 1.03 0.908 – 1.16 0.658 288 2877 all phecode
245.2 Chronic thyroiditis Endocrine/metabolic 1.03 0.893 – 1.18 0.702 218 2177 all phecode
245.21 Chronic lymphocytic thyroiditis Endocrine/metabolic 0.999 0.863 – 1.16 0.986 210 2097 all phecode
246 Other disorders of thyroid Endocrine/metabolic 0.983 0.885 – 1.09 0.748 397 3975 all phecode
250 Diabetes mellitus Endocrine/metabolic 1.2 1.18 – 1.22 3.42e-126 19787 186006 all phecode
250.1 Type 1 diabetes Endocrine/metabolic 1.13 1.09 – 1.18 5.74e-10 2758 27621 all phecode
250.11 Type 1 diabetes with ketoacidosis Endocrine/metabolic 1.07 0.936 – 1.23 0.316 239 2389 all phecode
250.12 Type 1 diabetes with renal manifestations Endocrine/metabolic 1.2 0.942 – 1.53 0.14 76 770 all phecode
250.13 Type 1 diabetes with ophthalmic manifestations Endocrine/metabolic 1.09 0.988 – 1.2 0.0867 473 4744 all phecode
250.14 Type 1 diabetes with neurological manifestations Endocrine/metabolic 1.11 0.943 – 1.3 0.216 160 1610 all phecode
250.2 Type 2 diabetes Endocrine/metabolic 1.21 1.19 – 1.23 2.17e-128 17831 170202 all phecode
250.21 Type 2 diabetes with ketoacidosis Endocrine/metabolic 1.11 0.911 – 1.36 0.294 104 1050 all phecode
250.22 Type 2 diabetes with renal manifestations Endocrine/metabolic 1.17 1.01 – 1.36 0.0344 200 2018 all phecode
250.23 Type 2 diabetes with ophthalmic manifestations Endocrine/metabolic 1.21 1.13 – 1.29 1.73e-08 986 9907 all phecode
250.24 Type 2 diabetes with neurological manifestations Endocrine/metabolic 1.18 1.07 – 1.29 0.000576 503 5066 all phecode
250.4 Abnormal glucose Endocrine/metabolic 1.16 1.07 – 1.25 0.000336 680 6827 all phecode
250.41 Impaired fasting glucose Endocrine/metabolic 1.18 1.04 – 1.35 0.00974 265 2659 all phecode
250.42 Other abnormal glucose Endocrine/metabolic 1.14 1.03 – 1.26 0.0133 416 4178 all phecode
250.5 Glycosuria or Acetonuria Endocrine/metabolic 1.1 0.922 – 1.31 0.294 131 1308 all phecode
250.6 Polyneuropathy in diabetes Endocrine/metabolic 1.21 1.08 – 1.36 0.000871 349 3495 all phecode
250.7 Diabetic retinopathy Endocrine/metabolic 1.13 1.06 – 1.19 4.65e-05 1329 13335 all phecode
251.1 Hypoglycemia Endocrine/metabolic 1.14 1.07 – 1.22 0.000134 932 9370 all phecode
252 Disorders of parathyroid gland Endocrine/metabolic 1.04 0.97 – 1.12 0.265 873 8719 all phecode
252.1 Hyperparathyroidism Endocrine/metabolic 1.05 0.976 – 1.14 0.185 781 7802 all phecode
252.2 Hypoparathyroidism Endocrine/metabolic 1.03 0.87 – 1.22 0.716 142 1418 all phecode
253
Disorders of the pituitary gland and its
Disorders of the pituitary gland and its hypothalamic control
 Endocrine/metabolic 1.08 0.993 – 1.16 0.0725 681 6821 all phecode
253.1 Pituitary hyperfunction Endocrine/metabolic 1.07 0.92 – 1.24 0.386 187 1867 all phecode
253.11 Acromegaly and gigantism Endocrine/metabolic 1.01 0.822 – 1.25 0.904 95 949 all phecode
253.2 Pituitary hypofunction Endocrine/metabolic 1.02 0.899 – 1.16 0.752 260 2618 all phecode
253.3 Diabetes insipidus Endocrine/metabolic 1.05 0.84 – 1.31 0.666 92 919 all phecode
253.7 Other disorders of neurohypophysis Endocrine/metabolic 1.18 1.01 – 1.38 0.0376 158 1578 all phecode
255 Disorders of adrenal glands Endocrine/metabolic 1.09 1 – 1.18 0.0397 638 6374 all phecode
255.1 Adrenal hyperfunction Endocrine/metabolic 1.05 0.899 – 1.22 0.549 180 1797 all phecode
255.11 Cushing's syndrome Endocrine/metabolic 1.14 0.929 – 1.4 0.212 103 1029 all phecode
255.12 Hyperaldosteronism Endocrine/metabolic 0.912 0.72 – 1.15 0.444 76 759 all phecode
255.2 Adrenal hypofunction Endocrine/metabolic 1.02 0.916 – 1.14 0.708 362 3617 all phecode
255.21 Glucocorticoid deficiency Endocrine/metabolic 1.03 0.921 – 1.14 0.632 361 3607 all phecode
256 Ovarian dysfunction Endocrine/metabolic 0.903 0.79 – 1.03 0.134 240 2397 all phecode
256.4 Polycystic ovaries Endocrine/metabolic 0.909 0.788 – 1.05 0.191 209 2088 all phecode
257 Testicular dysfunction Endocrine/metabolic 0.993 0.844 – 1.17 0.934 160 1619 all phecode
257.1 Testicular hypofunction Endocrine/metabolic 0.972 0.823 – 1.15 0.742 152 1539 all phecode
258 Iatrogenic endocrine disorders Endocrine/metabolic 1.06 0.863 – 1.29 0.593 102 1020 all phecode
259 Other endocrine disorders Endocrine/metabolic 0.927 0.781 – 1.1 0.387 149 1498 all phecode
260 Protein-calorie malnutrition Endocrine/metabolic 1.17 1.02 – 1.36 0.0296 202 2018 all phecode
260.1 Cachexia Endocrine/metabolic 1.46 1.11 – 1.92 0.00698 51 510 all phecode
260.6 Anorexia Endocrine/metabolic 1.1 1.03 – 1.19 0.00693 830 8317 all phecode
261 Vitamin deficiency Endocrine/metabolic 1.14 1.08 – 1.21 1.37e-05 1199 11974 all phecode
261.2 Vitamin B-complex deficiencies Endocrine/metabolic 1.2 1.11 – 1.3 2.53e-06 755 7541 all phecode
261.4 Vitamin D deficiency Endocrine/metabolic 1.03 0.936 – 1.14 0.512 447 4462 all phecode
261.41 Rickets or osteomalacia Endocrine/metabolic 0.944 0.742 – 1.2 0.642 77 769 all phecode
262 Mineral deficiency NEC Endocrine/metabolic 0.937 0.82 – 1.07 0.338 241 2407 all phecode
269 Proteinuria Endocrine/metabolic 1.15 1.03 – 1.28 0.0149 338 3378 all phecode
270
Disorders of protein plasma/amino-acid
Disorders of protein plasma/amino-acid transport and metabolism
 Endocrine/metabolic 1.16 1.03 – 1.3 0.017 303 3028 all phecode
270.3 Disorders of plasma protein metabolism Endocrine/metabolic 1.15 1.01 – 1.31 0.0308 261 2608 all phecode
270.32 Paraproteinemia Endocrine/metabolic 1.25 1.07 – 1.46 0.00394 191 1910 all phecode
270.33 Amyloidosis Endocrine/metabolic 0.971 0.802 – 1.18 0.763 113 1129 all phecode
270.35 Macroglobulinemia Endocrine/metabolic 0.869 0.689 – 1.1 0.237 69 689 all phecode
271
Disorders of carbohydrate transport and
Disorders of carbohydrate transport and metabolism
 Endocrine/metabolic 0.967 0.822 – 1.14 0.684 160 1600 all phecode
271.3
Intestinal disaccharidase deficiencies and
Intestinal disaccharidase deficiencies and disaccharide malabsorption
 Endocrine/metabolic 0.976 0.819 – 1.16 0.789 139 1391 all phecode
272 Disorders of lipoid metabolism Endocrine/metabolic 1.17 1.15 – 1.18 1.86e-154 34835 235433 all phecode
272.1 Hyperlipidemia Endocrine/metabolic 1.17 1.16 – 1.18 1.69e-154 34764 235203 all phecode
272.11 Hypercholesterolemia Endocrine/metabolic 1.17 1.16 – 1.18 1.43e-148 32324 228083 all phecode
272.12 Hyperglyceridemia Endocrine/metabolic 1.05 0.805 – 1.36 0.726 58 580 all phecode
272.13 Mixed hyperlipidemia Endocrine/metabolic 1.25 1.06 – 1.47 0.00642 164 1637 all phecode
272.9 Unspecified disorder of lipoid metabolism Endocrine/metabolic 1.08 0.935 – 1.24 0.304 211 2109 all phecode
274 Gout and other crystal arthropathies Endocrine/metabolic 1.23 1.19 – 1.27 6.85e-33 3724 37231 all phecode
274.1 Gout Endocrine/metabolic 1.25 1.2 – 1.3 2.12e-32 3171 31705 all phecode
274.11 Gouty arthropathy Endocrine/metabolic 1.19 0.985 – 1.43 0.0723 112 1119 all phecode
274.2 Crystal arthropathies Endocrine/metabolic 1.13 1.04 – 1.23 0.00348 613 6124 all phecode
274.21 Chondrocalcinosis Endocrine/metabolic 1.16 1.06 – 1.26 0.00111 558 5576 all phecode
275 Disorders of mineral metabolism Endocrine/metabolic 1.14 1.09 – 1.19 7.91e-09 2107 21070 all phecode
275.1 Disorders of iron metabolism Hematopoietic 1.06 0.978 – 1.15 0.157 653 6535 all phecode
275.3 Disorders of magnesium metabolism Endocrine/metabolic 1.24 1.12 – 1.38 6.99e-05 375 3745 all phecode
275.5 Disorders of calcium/phosphorus metabolism Endocrine/metabolic 1.17 1.1 – 1.24 3.74e-07 1202 12019 all phecode
275.53 Disorders of phosphorus metabolism Endocrine/metabolic 1.21 1.03 – 1.41 0.0181 171 1717 all phecode
276
Disorders of fluid, electrolyte, and acid-base
Disorders of fluid, electrolyte, and acid-base balance
 Endocrine/metabolic 1.15 1.12 – 1.18 1.78e-29 7284 72932 all phecode
276.1 Electrolyte imbalance Endocrine/metabolic 1.13 1.09 – 1.17 2.28e-13 4086 40930 all phecode
276.11 Hyperosmolality and/or hypernatremia Endocrine/metabolic 1 0.88 – 1.14 0.975 239 2409 all phecode
276.12 Hyposmolality and/or hyponatremia Endocrine/metabolic 1.14 1.08 – 1.19 3.17e-07 1818 18200 all phecode
276.13 Hyperpotassemia Endocrine/metabolic 1.14 1.07 – 1.21 0.000113 969 9728 all phecode
276.14 Hypopotassemia Endocrine/metabolic 1.15 1.09 – 1.22 7.55e-07 1424 14235 all phecode
276.4 Acid-base balance disorder Endocrine/metabolic 1.25 1.17 – 1.33 1.13e-12 1161 11629 all phecode
276.41 Acidosis Endocrine/metabolic 1.24 1.17 – 1.33 2.41e-11 1056 10577 all phecode
276.42 Alkalosis Endocrine/metabolic 1.3 1.06 – 1.58 0.0104 113 1129 all phecode
276.5 Hypovolemia Endocrine/metabolic 1.13 1.08 – 1.17 1.57e-09 2827 28265 all phecode
276.6 Fluid overload Endocrine/metabolic 1.23 1.12 – 1.35 3.16e-05 451 4535 all phecode
276.8 Polydipsia Endocrine/metabolic 1.23 1.02 – 1.47 0.0266 128 1278 all phecode
277 Other disorders of metabolism Endocrine/metabolic 1.14 1.06 – 1.22 0.000204 899 8977 all phecode
277.4 Disorders of bilirubin excretion Endocrine/metabolic 0.914 0.821 – 1.02 0.0992 362 3613 all phecode
277.5 Other disorders of lipoid metabolism Endocrine/metabolic 1.16 1.01 – 1.33 0.0309 230 2298 all phecode
277.51 Lipoprotein disorders Endocrine/metabolic 1.27 0.947 – 1.71 0.11 52 520 all phecode
278 Overweight, obesity and other hyperalimentation Endocrine/metabolic 1.21 1.18 – 1.23 1.25e-75 10804 108289 all phecode
278.1 Obesity Endocrine/metabolic 1.21 1.19 – 1.24 8.83e-77 10642 106670 all phecode
278.3 Localized adiposity Endocrine/metabolic 1.03 0.834 – 1.28 0.759 84 838 all phecode
278.4 Abnormal weight gain Endocrine/metabolic 0.903 0.703 – 1.16 0.422 66 660 all phecode
279 Disorders involving the immune mechanism Endocrine/metabolic 1.08 0.943 – 1.23 0.278 250 2510 all phecode
279.1 Immunity deficiency Endocrine/metabolic 1.09 0.947 – 1.26 0.225 209 2100 all phecode
279.11 Deficiency of humoral immunity Endocrine/metabolic 1.07 0.897 – 1.28 0.453 138 1390 all phecode
279.7 Other immunological findings Endocrine/metabolic 0.914 0.807 – 1.04 0.161 248 2478 all phecode
280 Iron deficiency anemias Hematopoietic 1.05 1.02 – 1.07 7.43e-05 7610 76168 all phecode
280.1
Iron deficiency anemias, unspecified or not due
Iron deficiency anemias, unspecified or not due to blood loss
 Hematopoietic 1.05 1.02 – 1.07 0.000114 7311 73153 all phecode
280.2
Iron deficiency anemia secondary to blood loss
Iron deficiency anemia secondary to blood loss (chronic)
 Hematopoietic 0.978 0.887 – 1.08 0.655 452 4541 all phecode
281 Other deficiency anemia Hematopoietic 1.15 1.08 – 1.23 1.02e-05 1112 11126 all phecode
281.1 Megaloblastic anemia Hematopoietic 1.14 1.07 – 1.22 4.59e-05 1066 10669 all phecode
281.11 Pernicious anemia Hematopoietic 1.16 1.07 – 1.25 0.000165 750 7514 all phecode
281.12 Other vitamin B12 deficiency anemia Hematopoietic 1.06 0.907 – 1.23 0.483 177 1769 all phecode
281.13 Folate-deficiency anemia Hematopoietic 1.11 0.95 – 1.29 0.192 183 1836 all phecode
281.9 Deficiency anemias Hematopoietic 1.38 1.02 – 1.87 0.0392 54 538 all phecode
282 Hereditary hemolytic anemias Hematopoietic 1.15 0.971 – 1.37 0.105 150 1499 all phecode
282.8 Other hemoglobinopathies Hematopoietic 1.19 0.908 – 1.55 0.212 56 560 all phecode
282.9 Other hereditary hemolytic anemias Hematopoietic 1.14 0.916 – 1.43 0.235 85 849 all phecode
283 Acquired hemolytic anemias Hematopoietic 1.06 0.878 – 1.27 0.566 135 1377 all phecode
283.1 Autoimmune hemolytic anemias Hematopoietic 1.1 0.89 – 1.35 0.389 103 1059 all phecode
284 Aplastic anemia Hematopoietic 1.17 1.06 – 1.29 0.00206 435 4357 all phecode
285 Other anemias Hematopoietic 1.07 1.05 – 1.09 5.46e-11 12104 121094 all phecode
285.1 Acute posthemorrhagic anemia Hematopoietic 1.1 0.965 – 1.24 0.157 271 2707 all phecode
285.2 Anemia of chronic disease Hematopoietic 1.11 1.03 – 1.2 0.00947 697 6980 all phecode
285.22 Anemia in neoplastic disease Hematopoietic 1.03 0.932 – 1.14 0.541 414 4147 all phecode
286 Coagulation defects Hematopoietic 1.11 1.03 – 1.18 0.00408 921 9218 all phecode
286.1 Congenital coagulation defects Hematopoietic 1.09 0.987 – 1.2 0.0894 459 4594 all phecode
286.11 Von willebrand's disease Hematopoietic 1.09 0.885 – 1.35 0.408 96 959 all phecode
286.12
Congenital deficiency of other clotting factors
Congenital deficiency of other clotting factors (including factor VII)
 Hematopoietic 1.13 1 – 1.28 0.0473 294 2944 all phecode
286.13 Congenital factor VIII disorder Hematopoietic 1.2 0.925 – 1.55 0.171 63 630 all phecode
286.5
Hemorrhagic disorder due to intrinsic
Hemorrhagic disorder due to intrinsic circulating anticoagulants
 Hematopoietic 1.14 0.912 – 1.42 0.253 86 860 all phecode
286.7 Other and unspecified coagulation defects Hematopoietic 1.14 1.03 – 1.27 0.0134 386 3867 all phecode
287 Purpura and other hemorrhagic conditions Hematopoietic 1.03 0.976 – 1.08 0.311 1652 16532 all phecode
287.1 Spontaneous ecchymoses Hematopoietic 1.06 0.882 – 1.28 0.522 129 1290 all phecode
287.2 Allergic purpura Hematopoietic 1.07 0.798 – 1.44 0.639 51 510 all phecode
287.3 Thrombocytopenia Hematopoietic 1.03 0.975 – 1.08 0.309 1553 15543 all phecode
287.31 Primary thrombocytopenia Hematopoietic 1 0.903 – 1.11 0.997 419 4195 all phecode
287.32 Secondary thrombocytopenia Hematopoietic 1.07 0.844 – 1.36 0.573 75 749 all phecode
288 Diseases of white blood cells Hematopoietic 1.01 0.979 – 1.05 0.452 3765 37672 all phecode
288.1 Decreased white blood cell count Hematopoietic 1.01 0.976 – 1.05 0.507 3168 31704 all phecode
288.11 Neutropenia Hematopoietic 1.01 0.976 – 1.05 0.516 3176 31784 all phecode
288.3 Eosinophilia Hematopoietic 0.882 0.694 – 1.12 0.309 71 709 all phecode
289 Other diseases of blood and blood-forming organs Hematopoietic 1.1 1.02 – 1.18 0.0105 862 8625 all phecode
289.3
Personal history of diseases of blood and
Personal history of diseases of blood and blood-forming organs
 Hematopoietic 1.06 0.937 – 1.2 0.353 290 2897 all phecode
289.4 Lymphadenitis Hematopoietic 1.14 1.09 – 1.19 3.73e-10 2602 26061 all phecode
289.5 Diseases of spleen Hematopoietic 1.07 0.978 – 1.18 0.137 516 5153 all phecode
289.8 Polycythemia, secondary Hematopoietic 1.33 1.18 – 1.5 4.26e-06 292 2917 all phecode
289.9 Abnormality of red blood cells Hematopoietic 1.19 0.961 – 1.48 0.11 90 900 all phecode
290
Delirium dementia and amnestic and other
Delirium dementia and amnestic and other cognitive disorders
 Mental Disorders 1.12 1.07 – 1.17 3.56e-06 1929 19281 all phecode
290.1 Dementias Mental Disorders 1.02 0.959 – 1.09 0.487 1004 10032 all phecode
290.11 Alzheimer's disease Mental Disorders 0.966 0.874 – 1.07 0.491 431 4307 all phecode
290.16 Vascular dementia Mental Disorders 1.12 0.975 – 1.3 0.108 201 2008 all phecode
290.2 Delirium due to conditions classified elsewhere Mental Disorders 1.18 1.09 – 1.28 6.34e-05 650 6501 all phecode
290.3
Other persistent mental disorders due to
Other persistent mental disorders due to conditions classified elsewhere
 Mental Disorders 1.74 1.36 – 2.23 1.25e-05 70 709 all phecode
291
Other specified nonpsychotic and/or transient
Other specified nonpsychotic and/or transient mental disorders
 Mental Disorders 1.17 1.09 – 1.25 2.66e-05 836 8385 all phecode
291.1
Transient mental disorders due to conditions
Transient mental disorders due to conditions classified elsewhere
 Mental Disorders 1.07 0.889 – 1.28 0.48 132 1320 all phecode
291.4
Specific nonpsychotic mental disorders due to
Specific nonpsychotic mental disorders due to brain damage
 Mental Disorders 1.16 1.02 – 1.31 0.02 286 2867 all phecode
291.8 Alteration of consciousness Mental Disorders 1.2 1.09 – 1.32 0.000307 436 4376 all phecode
292 Neurological disorders Mental Disorders 1.1 1.06 – 1.13 2.34e-09 4621 46260 all phecode
292.1 Aphasia/speech disturbance Mental Disorders 1.12 1.07 – 1.19 1.51e-05 1504 15074 all phecode
292.2 Mild cognitive impairment Mental Disorders 1.14 0.977 – 1.33 0.0965 190 1907 all phecode
292.3 Memory loss Mental Disorders 1.03 0.953 – 1.12 0.44 696 6978 all phecode
292.4 Altered mental status Mental Disorders 1.1 1.06 – 1.15 1.36e-05 2181 21827 all phecode
292.6 Hallucinations Mental Disorders 1.11 0.986 – 1.25 0.0855 307 3073 all phecode
293 Symptoms involving head and neck Mental Disorders 1.14 1.09 – 1.19 3.7e-08 2078 20779 all phecode
293.1
Swelling, mass, or lump in head and neck
Swelling, mass, or lump in head and neck [Space-occupying lesion, intracranial NOS]
 Mental Disorders 1.13 1.05 – 1.21 0.000529 901 9010 all phecode
295 Schizophrenia and other psychotic disorders Mental Disorders 1.32 1.23 – 1.42 3.52e-14 841 8446 all phecode
295.1 Schizophrenia Mental Disorders 1.31 1.2 – 1.43 7.62e-10 574 5766 all phecode
295.2 Paranoid disorders Mental Disorders 1.31 1.12 – 1.53 0.000577 178 1780 all phecode
295.3 Psychosis Mental Disorders 1.25 1.06 – 1.48 0.00709 169 1710 all phecode
296 Mood disorders Mental Disorders 1.26 1.23 – 1.28 1.06e-125 12372 123822 all phecode
296.1 Bipolar Mental Disorders 1.19 1.12 – 1.27 9.06e-08 1059 10599 all phecode
296.2 Depression Mental Disorders 1.26 1.24 – 1.29 1.64e-122 11737 117469 all phecode
296.22 Major depressive disorder Mental Disorders 1.19 1.06 – 1.33 0.00231 361 3604 all phecode
297.2 Suicide or self-inflicted injury Mental Disorders 1.46 1.29 – 1.65 1.03e-09 311 3070 all phecode
300 Anxiety disorders Mental Disorders 1.15 1.13 – 1.18 7.77e-29 6844 68484 all phecode
300.1 Anxiety disorder Mental Disorders 1.15 1.12 – 1.19 1.28e-26 6324 63282 all phecode
300.11 Generalized anxiety disorder Mental Disorders 1 0.845 – 1.18 0.995 149 1499 all phecode
300.12 Agorophobia, social phobia, and panic disorder Mental Disorders 1.16 1.08 – 1.26 0.000148 707 7065 all phecode
300.13 Phobia Mental Disorders 1.18 1.07 – 1.29 0.000776 501 5013 all phecode
300.3 Obsessive-compulsive disorders Mental Disorders 1.05 0.881 – 1.26 0.574 140 1407 all phecode
300.4 Dysthymic disorder Mental Disorders 1.32 0.995 – 1.75 0.0539 53 530 all phecode
300.8 Acute reaction to stress Mental Disorders 1.24 1.03 – 1.49 0.0212 124 1238 all phecode
300.9 Posttraumatic stress disorder Mental Disorders 1.33 1.09 – 1.61 0.0043 113 1129 all phecode
301 Personality disorders Mental Disorders 1.34 1.19 – 1.51 8.84e-07 334 3338 all phecode
301.2 Antisocial/borderline personality disorder Mental Disorders 1.39 1.14 – 1.68 0.000851 119 1186 all phecode
302 Sexual and gender identity disorders Mental Disorders 1.27 1.13 – 1.43 0.000106 283 2845 all phecode
303 Psychogenic and somatoform disorders Mental Disorders 1.15 1.04 – 1.27 0.00446 467 4679 all phecode
303.3 Psychogenic disorder Mental Disorders 1.17 1.04 – 1.31 0.0067 350 3510 all phecode
303.4 Somatoform disorder Mental Disorders 1.11 0.915 – 1.34 0.298 123 1229 all phecode
304 Adjustment reaction Mental Disorders 1.18 1.05 – 1.34 0.00598 293 2936 all phecode
305.2 Eating disorder Mental Disorders 0.935 0.753 – 1.16 0.541 90 900 all phecode
306 Other mental disorder Mental Disorders 1.84 1.82 – 1.87 7.83e-1731 28056 230087 all phecode
306.9 Tension headache Mental Disorders 1.21 1.08 – 1.37 0.00138 315 3148 all phecode
313 Pervasive developmental disorders Mental Disorders 0.917 0.723 – 1.16 0.473 76 770 all phecode
313.3 Autism Mental Disorders 0.95 0.719 – 1.25 0.716 53 539 all phecode
315 Develomental delays and disorders Mental Disorders 1.14 1.02 – 1.28 0.0184 351 3517 all phecode
315.1 Learning disorder Mental Disorders 0.981 0.837 – 1.15 0.815 161 1610 all phecode
315.2 Speech and language disorder Mental Disorders 1.37 1.1 – 1.71 0.00572 88 880 all phecode
316 Substance addiction and disorders Mental Disorders 1.47 1.43 – 1.52 5.4e-151 5313 53131 all phecode
316.1 Polyneuropathy due to drugs Mental Disorders 1.16 0.897 – 1.49 0.263 60 599 all phecode
317 Alcohol-related disorders Mental Disorders 1.32 1.29 – 1.34 1.51e-184 12696 126892 all phecode
317.1 Alcoholism Mental Disorders 1.27 1.24 – 1.3 4.71e-101 8890 88923 all phecode
317.11 Alcoholic liver damage Mental Disorders 1.49 1.38 – 1.6 4.17e-26 838 8392 all phecode
318 Tobacco use disorder Mental Disorders 2.07 2.03 – 2.1 2.5e-1665 19359 185465 all phecode
320 Meningitis Neurological 1.08 0.981 – 1.19 0.114 444 4447 all phecode
323 Encephalitis Neurological 1.06 0.947 – 1.19 0.312 342 3422 all phecode
323.2 Acute (transverse) myelitis Neurological 1.04 0.816 – 1.32 0.758 74 739 all phecode
324 Other CNS infection and poliomyelitis Neurological 0.966 0.856 – 1.09 0.569 292 2916 all phecode
327 Sleep disorders Neurological 1.18 1.11 – 1.25 9.26e-08 1164 11659 all phecode
327.3 Sleep apnea Neurological 1.19 1.15 – 1.22 1.56e-26 4428 44318 all phecode
327.4 Insomnia Neurological 1.23 1.05 – 1.44 0.0108 163 1660 all phecode
327.41 Organic or persistent insomnia Neurological 1.18 0.995 – 1.39 0.0574 136 1390 all phecode
331 Other cerebral degenerations Neurological 1.1 1.04 – 1.17 0.00127 1142 11416 all phecode
331.1 Hydrocephalus Neurological 1.1 1.01 – 1.21 0.0356 502 5014 all phecode
331.9 Cerebral degeneration, unspecified Neurological 1.11 1 – 1.22 0.0439 430 4298 all phecode
332 Parkinson's disease Neurological 0.916 0.862 – 0.974 0.00486 1126 11254 all phecode
333
Extrapyramidal disease and abnormal movement
Extrapyramidal disease and abnormal movement disorders
 Neurological 1.09 1.02 – 1.17 0.0165 894 8954 all phecode
333.1 Essential tremor Neurological 1.18 1.02 – 1.36 0.023 216 2157 all phecode
333.2 Myoclonus Neurological 1.13 0.913 – 1.39 0.264 96 958 all phecode
333.4 Torsion dystonia Neurological 0.992 0.87 – 1.13 0.908 253 2528 all phecode
334 Degenerative disease of the spinal cord Neurological 1.11 1.06 – 1.17 3.2e-05 1812 18130 all phecode
334.1 Spinocerebellar disease Neurological 1.01 0.838 – 1.21 0.93 117 1169 all phecode
334.2 Anterior horn cell disease Neurological 0.951 0.832 – 1.09 0.457 245 2446 all phecode
335 Multiple sclerosis Neurological 1.12 1.06 – 1.19 5.28e-05 1340 13385 all phecode
337 Disorders of the autonomic nervous system Neurological 1.1 0.968 – 1.24 0.148 266 2668 all phecode
337.1 Peripheral autonomic neuropathy Neurological 1.2 0.944 – 1.52 0.138 72 719 all phecode
338 Pain Neurological 1.18 1.1 – 1.28 1.28e-05 768 7692 all phecode
338.1 Acute pain Neurological 1.13 1.01 – 1.25 0.0282 394 3937 all phecode
338.2 Chronic pain Neurological 1.25 1.12 – 1.4 4.28e-05 380 3817 all phecode
339 Other headache syndromes Neurological 1.12 1.09 – 1.14 1.85e-20 7819 78241 all phecode
340 Migraine Neurological 1.05 1.01 – 1.09 0.0144 2860 28602 all phecode
340.1 Migrain with aura Neurological 1.09 0.948 – 1.26 0.22 212 2117 all phecode
341
Other demyelinating diseases of central nervous
Other demyelinating diseases of central nervous system
 Neurological 1.22 1.07 – 1.39 0.00353 252 2535 all phecode
342 Hemiplegia Neurological 1.16 1.1 – 1.23 5.31e-08 1494 14947 all phecode
343 Infantile cerebral palsy Neurological 0.861 0.724 – 1.02 0.0875 145 1450 all phecode
344 Other paralytic syndromes Neurological 1.18 1.08 – 1.27 9.92e-05 658 6593 all phecode
345 Epilepsy, recurrent seizures, convulsions Neurological 1.1 1.07 – 1.13 1.27e-10 5023 50270 all phecode
345.1 Epilepsy Neurological 1.08 1 – 1.16 0.0363 866 8661 all phecode
345.11 Generalized convulsive epilepsy Neurological 1.1 0.993 – 1.21 0.069 439 4385 all phecode
345.12 Partial epilepsy Neurological 1.05 0.924 – 1.18 0.474 277 2776 all phecode
345.3 Convulsions Neurological 1.07 1.03 – 1.12 0.00163 2235 22339 all phecode
346.1
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of skull and head
 Neurological 1.12 0.944 – 1.33 0.191 144 1438 all phecode
348 Other conditions of brain Neurological 1.15 1.07 – 1.24 0.000176 778 7808 all phecode
348.2 Cerebral edema and compression of brain Neurological 1.18 1.04 – 1.33 0.0118 268 2678 all phecode
348.4 Cerebral cysts Neurological 0.938 0.786 – 1.12 0.473 133 1350 all phecode
348.7 Coma Neurological 1.03 0.927 – 1.15 0.558 358 3596 all phecode
348.8 Encephalopathy, not elsewhere classified Neurological 1.15 1.01 – 1.31 0.0341 249 2504 all phecode
348.9 Other conditions of brain, NOS Neurological 1.09 0.98 – 1.21 0.113 390 3899 all phecode
349
Other and unspecified disorders of the nervous
Other and unspecified disorders of the nervous system
 Neurological 1.1 0.987 – 1.23 0.0853 342 3414 all phecode
350 Abnormal movement Neurological 1.11 1.07 – 1.15 4.46e-07 2671 26722 all phecode
350.1 Abnormal involuntary movements Neurological 1.12 1.05 – 1.21 0.0012 887 8852 all phecode
350.2 Abnormality of gait Neurological 1.13 1.07 – 1.19 7.35e-06 1596 15969 all phecode
350.3 Lack of coordination Neurological 0.994 0.892 – 1.11 0.908 363 3638 all phecode
350.6 Disturbances of sensation of smell and taste Neurological 1.03 0.779 – 1.35 0.858 54 540 all phecode
351 Other peripheral nerve disorders Neurological 1.15 1.13 – 1.18 7.47e-50 12420 124321 all phecode
352 Disorders of other cranial nerves Neurological 1.1 1.04 – 1.16 0.00144 1370 13706 all phecode
352.1 Trigeminal nerve disorders [CN5] Neurological 1.16 1.05 – 1.28 0.00283 463 4638 all phecode
352.2 Facial nerve disorders [CN7] Neurological 1.08 1.01 – 1.16 0.0242 880 8795 all phecode
353 Nerve root and plexus disorders Neurological 1.19 1.12 – 1.26 4.68e-08 1131 11319 all phecode
353.1 Nerve plexus lesions Neurological 1.05 0.865 – 1.27 0.627 114 1138 all phecode
353.2 Nerve root lesions Neurological 1.02 0.763 – 1.35 0.917 57 570 all phecode
356 Hereditary and idiopathic peripheral neuropathy Neurological 1.2 1.01 – 1.42 0.0378 152 1520 all phecode
357 Inflammatory and toxic neuropathy Neurological 1.08 1.03 – 1.15 0.00464 1361 13648 all phecode
358 Myoneural disorders Neurological 1.1 0.955 – 1.27 0.183 211 2109 all phecode
358.1 Myasthenia gravis Neurological 1.08 0.931 – 1.26 0.305 192 1919 all phecode
359 Muscular dystrophies and other myopathies Neurological 1.04 0.948 – 1.15 0.385 465 4646 all phecode
359.1 Muscular dystrophies Neurological 1.08 0.9 – 1.3 0.397 122 1219 all phecode
359.2 Myopathy Neurological 1.03 0.926 – 1.15 0.557 360 3597 all phecode
360 Disorders of the globe Sense Organs 0.964 0.861 – 1.08 0.525 337 3367 all phecode
360.2 Progressive myopia Sense Organs 0.901 0.79 – 1.03 0.118 251 2508 all phecode
361 Retinal detachments and defects Sense Organs 0.927 0.894 – 0.961 4.05e-05 3246 32453 all phecode
361.1 Retinal detachment with retinal defect Sense Organs 0.933 0.883 – 0.986 0.0145 1389 13884 all phecode
361.2 Retinoschisis and retinal cysts Sense Organs 0.848 0.662 – 1.09 0.192 68 680 all phecode
362 Other retinal disorders Sense Organs 1.03 0.998 – 1.07 0.0651 3836 38370 all phecode
362.2
Degeneration of macula and posterior pole of
Degeneration of macula and posterior pole of retina
 Sense Organs 1.04 0.999 – 1.09 0.0556 2182 21813 all phecode
362.29 Macular degeneration (senile) of retina NOS Sense Organs 1.04 0.997 – 1.09 0.0654 2179 21783 all phecode
362.3 Other nondiabetic retinopathy Sense Organs 0.872 0.741 – 1.03 0.0967 161 1609 all phecode
362.31 Separation of retinal layers Sense Organs 0.83 0.674 – 1.02 0.0794 99 990 all phecode
362.4 Retinal vascular changes and abnomalities Sense Organs 1.06 0.99 – 1.14 0.0935 848 8477 all phecode
362.6 Peripheral retinal degenerations Sense Organs 0.971 0.833 – 1.13 0.702 182 1827 all phecode
362.7 Hereditary retinal dystrophies Sense Organs 0.857 0.684 – 1.07 0.177 82 812 all phecode
362.8 Retinal hemorrhage/ischemia Sense Organs 1.06 0.867 – 1.28 0.589 116 1159 all phecode
363
Chorioretinal inflammations, scars, and other
Chorioretinal inflammations, scars, and other disorders of choroid
 Sense Organs 0.937 0.8 – 1.1 0.424 170 1699 all phecode
363.3 Chorioretinal scars Sense Organs 0.791 0.613 – 1.02 0.0734 69 690 all phecode
364 Corneal opacity and other disorders of cornea Sense Organs 0.944 0.869 – 1.02 0.168 647 6485 all phecode
364.1 Corneal opacity Sense Organs 1.02 0.822 – 1.26 0.862 90 910 all phecode
364.2 Corneal edema Sense Organs 0.915 0.732 – 1.14 0.438 79 800 all phecode
364.4 Corneal degenerations Sense Organs 0.875 0.755 – 1.01 0.0774 201 2017 all phecode
364.41 Keratoconus Sense Organs 0.769 0.617 – 0.959 0.0199 86 869 all phecode
364.5 Corneal dystrophy Sense Organs 1.08 0.939 – 1.25 0.272 211 2109 all phecode
364.9 Cornea replaced by transplant Sense Organs 0.955 0.776 – 1.17 0.662 100 1000 all phecode
365 Glaucoma Sense Organs 0.98 0.95 – 1.01 0.212 4408 44136 all phecode
365.1 Open-angle glaucoma Sense Organs 0.937 0.879 – 0.999 0.0463 1032 10346 all phecode
365.11 Primary open angle glaucoma Sense Organs 0.937 0.879 – 0.999 0.0462 1026 10287 all phecode
365.2 Primary angle-closure glaucoma Sense Organs 0.992 0.917 – 1.07 0.852 698 6996 all phecode
366 Cataract Sense Organs 1.04 1.03 – 1.06 1.71e-07 19926 168711 all phecode
366.1 Nonsenile Cataract Sense Organs 1.02 0.802 – 1.31 0.848 69 700 all phecode
366.2 Senile cataract Sense Organs 1.06 1.04 – 1.09 1.42e-07 8231 81909 all phecode
366.3 Traumatic cataract Sense Organs 0.967 0.794 – 1.18 0.742 102 1019 all phecode
367
Disorders of refraction and accommodation
Disorders of refraction and accommodation; blindness and low vision
 Sense Organs 1.03 0.986 – 1.07 0.191 2408 24092 all phecode
367.1 Myopia Sense Organs 0.974 0.918 – 1.03 0.389 1251 12519 all phecode
367.2 Astigmatism Sense Organs 1.02 0.88 – 1.19 0.752 190 1899 all phecode
367.8 Hypermetropia Sense Organs 1.1 0.96 – 1.25 0.176 253 2530 all phecode
367.9 Blindness and low vision Sense Organs 1.1 1.02 – 1.19 0.018 719 7198 all phecode
368 Visual disturbances Sense Organs 1.06 1.02 – 1.1 0.00172 2962 29648 all phecode
368.1 Amblyopia Sense Organs 1 0.914 – 1.09 0.997 532 5322 all phecode
368.2 Diplopia and disorders of binocular vision Sense Organs 1.1 1.02 – 1.19 0.0148 727 7288 all phecode
368.3 Anisometropia Sense Organs 0.968 0.819 – 1.14 0.704 154 1548 all phecode
368.4 Visual field defects Sense Organs 1.12 1 – 1.25 0.0508 333 3327 all phecode
368.9 Subjective visual disturbances Sense Organs 1.1 1.01 – 1.2 0.0227 612 6115 all phecode
369 Infection of the eye Sense Organs 0.966 0.885 – 1.05 0.441 553 5544 all phecode
369.2 Eye infection, viral Sense Organs 0.936 0.778 – 1.13 0.486 125 1257 all phecode
369.5 Conjunctivitis, infectious Sense Organs 0.886 0.768 – 1.02 0.0975 213 2128 all phecode
370 Keratitis Sense Organs 1.03 0.906 – 1.16 0.678 286 2855 all phecode
370.1 Corneal ulcer Sense Organs 0.957 0.803 – 1.14 0.625 141 1408 all phecode
371 Inflammation of the eye Sense Organs 0.984 0.948 – 1.02 0.413 3045 30480 all phecode
371.1 Uveitis, noninfectious or NOS Sense Organs 1.01 0.916 – 1.11 0.896 482 4821 all phecode
371.3 Inflammation of eyelids Sense Organs 0.968 0.927 – 1.01 0.134 2353 23555 all phecode
372 Disorders of conjunctiva Sense Organs 1.06 0.987 – 1.15 0.104 760 7602 all phecode
374 Other disorders of eyelids Sense Organs 1.06 1.03 – 1.09 0.000126 5680 56807 all phecode
374.1 Ectropion or entropion Sense Organs 1.06 0.997 – 1.13 0.0636 1063 10645 all phecode
374.3 Ptosis of eyelid Sense Organs 1.03 0.983 – 1.08 0.199 1825 18232 all phecode
375 Disorders of lacrimal system Sense Organs 1.04 0.999 – 1.09 0.0558 2204 22031 all phecode
375.2 Epiphora Sense Organs 1.02 0.954 – 1.1 0.519 898 8969 all phecode
376 Disorders of the orbit Sense Organs 1.01 0.807 – 1.27 0.925 86 859 all phecode
377 Disorders of optic nerve and visual pathways Sense Organs 1.02 0.915 – 1.14 0.698 361 3618 all phecode
377.1 Optic atrophy Sense Organs 0.969 0.728 – 1.29 0.831 56 570 all phecode
377.3 Optic neuritis/neuropathy Sense Organs 1.07 0.881 – 1.29 0.505 125 1249 all phecode
378
Strabismus and other disorders of binocular eye
Strabismus and other disorders of binocular eye movements
 Sense Organs 1.01 0.954 – 1.06 0.794 1410 14116 all phecode
378.1 Strabismus (not specified as paralytic) Sense Organs 0.994 0.928 – 1.06 0.863 909 9082 all phecode
378.2 Nystagmus and other irregular eye movements Sense Organs 0.961 0.836 – 1.11 0.581 213 2138 all phecode
378.5 Paralytic strabismus Sense Organs 1.07 0.942 – 1.21 0.308 275 2755 all phecode
379 Other disorders of eye Sense Organs 1.04 1 – 1.07 0.0447 3703 37063 all phecode
379.2 Disorders of vitreous body Sense Organs 0.96 0.908 – 1.02 0.156 1367 13665 all phecode
379.3 Aphakia and other disorders of lens Sense Organs 1.11 1.06 – 1.17 3.94e-05 1813 18134 all phecode
379.4 Anomalies of pupillary function Sense Organs 0.806 0.63 – 1.03 0.0845 71 710 all phecode
379.5 Disorders of iris and ciliary body Sense Organs 1.01 0.907 – 1.11 0.922 400 4028 all phecode
379.9 Pain, swelling or discharge of eye Sense Organs 1.14 0.978 – 1.33 0.0939 169 1690 all phecode
380 Disorders of external ear Sense Organs 1.2 1.1 – 1.3 1.34e-05 642 6413 all phecode
380.1 Otitis externa Sense Organs 1.19 1.09 – 1.3 0.000175 509 5107 all phecode
380.4 Impacted cerumen Sense Organs 0.968 0.868 – 1.08 0.564 362 3614 all phecode
381 Otitis media and Eustachian tube disorders Sense Organs 1.12 1.07 – 1.17 1.72e-06 2150 21493 all phecode
381.1 Otitis media Sense Organs 1.1 1.05 – 1.16 0.000166 1767 17668 all phecode
381.11 Suppurative and unspecified otitis media Sense Organs 1.19 1.1 – 1.27 3.13e-06 852 8524 all phecode
381.2 Eustachian tube disorders Sense Organs 1.04 0.901 – 1.21 0.564 193 1929 all phecode
381.3 Mastoiditis & related conditions Sense Organs 1.16 0.983 – 1.36 0.0792 171 1709 all phecode
381.9 Otorrhea Sense Organs 1.26 1.11 – 1.43 0.000336 281 2807 all phecode
382 Otalgia Sense Organs 1.05 0.935 – 1.19 0.39 308 3084 all phecode
383 Otosclerosis Sense Organs 1.04 0.929 – 1.17 0.468 309 3090 all phecode
384 Other disorders of tympanic membrane Sense Organs 1.17 1.1 – 1.24 2.2e-07 1299 12991 all phecode
384.4 Perforation of tympanic membrane Sense Organs 1.17 1.09 – 1.24 4.19e-06 1043 10432 all phecode
385 Other disorders of middle ear and mastoid Sense Organs 1.12 1.04 – 1.2 0.00382 783 7837 all phecode
385.3 Cholesteatoma Sense Organs 1.1 1.01 – 1.19 0.0345 607 6078 all phecode
385.5
Tympanosclerosis and middle ear disease related
Tympanosclerosis and middle ear disease related to otitis media
 Sense Organs 1.1 0.963 – 1.26 0.161 241 2409 all phecode
386
Vertiginous syndromes and other disorders of
Vertiginous syndromes and other disorders of vestibular system
 Sense Organs 1.03 0.977 – 1.08 0.298 1736 17373 all phecode
386.1 Meniere's disease Sense Organs 0.983 0.902 – 1.07 0.704 576 5768 all phecode
386.2 Peripheral or central vertigo Sense Organs 1.02 0.919 – 1.14 0.683 377 3763 all phecode
386.3 Labyrinthitis Sense Organs 1.04 0.962 – 1.12 0.345 765 7664 all phecode
386.9
Dizziness and giddiness (Light-headedness and
Dizziness and giddiness (Light-headedness and vertigo)
 Sense Organs 1.05 1.02 – 1.08 0.00352 4582 45806 all phecode
388 Other disorders of ear Sense Organs 1.04 0.9 – 1.21 0.569 202 2017 all phecode
389 Hearing loss Sense Organs 1.08 1.04 – 1.11 6.5e-06 4188 41944 all phecode
389.1 Sensorineural hearing loss Sense Organs 1.04 0.943 – 1.14 0.439 456 4553 all phecode
389.2 Conductive hearing loss Sense Organs 1.13 1.02 – 1.24 0.0165 450 4497 all phecode
389.4 Tinnitus Sense Organs 1.04 0.946 – 1.14 0.42 513 5134 all phecode
394 Rheumatic disease of the heart valves Circulatory System 1.07 1.04 – 1.1 7.23e-06 4899 48974 all phecode
394.2 Mitral valve disease Circulatory System 1.04 1 – 1.08 0.0325 2993 29922 all phecode
394.3 Aortic valve disease Circulatory System 1.08 1.02 – 1.14 0.011 1282 12814 all phecode
394.7 Disease of tricuspid valve Circulatory System 1.07 1.01 – 1.14 0.0345 1058 10566 all phecode
395 Heart valve disorders Circulatory System 1.06 1.03 – 1.09 0.000284 4223 42219 all phecode
395.1 Nonrheumatic mitral valve disorders Circulatory System 1.04 1.01 – 1.09 0.0264 2891 28900 all phecode
395.2 Nonrheumatic aortic valve disorders Circulatory System 1.09 0.963 – 1.23 0.175 276 2766 all phecode
395.3 Nonrheumatic tricuspid valve disorders Circulatory System 1.11 0.907 – 1.36 0.306 105 1039 all phecode
395.4 Nonrheumatic pulmonary valve disorders Circulatory System 1.1 0.901 – 1.35 0.344 97 970 all phecode
395.6 Heart valve replaced Circulatory System 1.06 1.01 – 1.12 0.0205 1495 14942 all phecode
396 Abnormal heart sounds Circulatory System 1 0.938 – 1.07 0.981 1048 10468 all phecode
401 Hypertension Circulatory System 1.13 1.12 – 1.14 2.41e-165 73956 266957 all phecode
401.1 Essential hypertension Circulatory System 1.13 1.12 – 1.14 2.69e-165 73731 266739 all phecode
401.2 Hypertensive heart and/or renal disease Circulatory System 1.17 1.11 – 1.23 1.4e-10 1898 19031 all phecode
401.21 Hypertensive heart disease Circulatory System 1.24 1.11 – 1.39 9.46e-05 370 3699 all phecode
401.22 Hypertensive chronic kidney disease Circulatory System 1.15 1.09 – 1.22 1.01e-07 1543 15483 all phecode
401.3 Other hypertensive complications Circulatory System 1.42 1.19 – 1.68 6.54e-05 144 1438 all phecode
402
Elevated blood pressure reading without
Elevated blood pressure reading without diagnosis of hypertension
 Circulatory System 1.13 1.07 – 1.19 9.8e-06 1479 14786 all phecode
411 Ischemic Heart Disease Circulatory System 1.19 1.18 – 1.21 8.88e-180 31245 210714 all phecode
411.1 Unstable angina (intermediate coronary syndrome) Circulatory System 1.25 1.22 – 1.29 1.59e-51 5152 51498 all phecode
411.2 Myocardial infarction Circulatory System 1.25 1.22 – 1.27 4.5e-114 11950 112699 all phecode
411.3 Angina pectoris Circulatory System 1.21 1.19 – 1.23 1.66e-113 15888 143745 all phecode
411.4 Coronary atherosclerosis Circulatory System 1.2 1.18 – 1.21 1.23e-122 20171 154621 all phecode
411.41 Aneurysm and dissection of heart Circulatory System 1.03 0.949 – 1.11 0.511 700 6997 all phecode
411.8
Other chronic ischemic heart disease
Other chronic ischemic heart disease, unspecified
 Circulatory System 1.26 1.24 – 1.28 8.04e-154 15290 131798 all phecode
411.9
Other acute and subacute forms of ischemic
Other acute and subacute forms of ischemic heart disease
 Circulatory System 1.22 1.15 – 1.29 1.19e-10 1218 12166 all phecode
414 Other forms of chronic heart disease Circulatory System 1.21 1.15 – 1.27 1.52e-14 1823 18228 all phecode
414.2 ASCVD Circulatory System 1.54 1.2 – 1.97 0.000564 72 719 all phecode
415 Pulmonary heart disease Circulatory System 1.09 1.06 – 1.13 2.23e-08 4476 44810 all phecode
415.11 Pulmonary embolism and infarction, acute Circulatory System 0.968 0.772 – 1.22 0.781 75 750 all phecode
415.2 Chronic pulmonary heart disease Circulatory System 1.15 1.06 – 1.25 0.00118 601 6002 all phecode
415.21 Primary pulmonary hypertension Circulatory System 1.09 0.988 – 1.2 0.0855 448 4475 all phecode
416 Cardiomegaly Circulatory System 1.11 1.07 – 1.16 1.3e-07 2680 26793 all phecode
418 Nonspecific chest pain Circulatory System 1.13 1.11 – 1.14 1.56e-79 28599 270106 all phecode
418.1 Precordial pain Circulatory System 1.11 1.07 – 1.15 1.05e-08 3551 35541 all phecode
420 Carditis Circulatory System 1.08 1.03 – 1.13 0.000993 2106 21053 all phecode
420.1 Myocarditis Circulatory System 1.41 1.17 – 1.7 0.000338 127 1267 all phecode
420.2 Pericarditis Circulatory System 1.07 1.01 – 1.14 0.0159 1338 13371 all phecode
420.21 Acute pericarditis Circulatory System 1.2 1.04 – 1.37 0.0103 223 2227 all phecode
420.22 Chronic pericarditis Circulatory System 1.25 1.03 – 1.51 0.0239 113 1129 all phecode
420.3 Endocarditis Circulatory System 1.05 0.975 – 1.14 0.188 719 7194 all phecode
425 Cardiomyopathy Circulatory System 1.09 1.02 – 1.15 0.00571 1271 12699 all phecode
425.1 Primary/intrinsic cardiomyopathies Circulatory System 1.08 1.02 – 1.15 0.00738 1236 12349 all phecode
425.11 Hypertrophic obstructive cardiomyopathy Circulatory System 0.928 0.779 – 1.1 0.401 133 1329 all phecode
425.12 Other hypertrophic cardiomyopathy Circulatory System 1.03 0.871 – 1.21 0.748 163 1629 all phecode
425.8 Other cardiomyopathy Circulatory System 1.27 0.971 – 1.66 0.0809 60 600 all phecode
426 Cardiac conduction disorders Circulatory System 1.11 1.08 – 1.13 2.02e-15 6910 69146 all phecode
426.2 Atrioventricular [AV] block Circulatory System 1.07 1.03 – 1.12 0.00187 2114 21162 all phecode
426.21 First degree AV block Circulatory System 1.03 0.963 – 1.1 0.417 986 9867 all phecode
426.23 Second degree AV block Circulatory System 1.07 0.972 – 1.18 0.168 452 4515 all phecode
426.24 Atrioventricular block, complete Circulatory System 1.06 0.979 – 1.16 0.145 587 5868 all phecode
426.25 Other heart block Circulatory System 1.28 1.07 – 1.53 0.00778 131 1318 all phecode
426.3 Bundle branch block Circulatory System 1.11 1.07 – 1.15 1.36e-08 3336 33359 all phecode
426.31 Right bundle branch block Circulatory System 1.11 1.05 – 1.17 0.000102 1494 14933 all phecode
426.32 Left bundle branch block Circulatory System 1.12 1.06 – 1.17 9.7e-06 1750 17503 all phecode
426.4 Anomalous atrioventricular excitation Circulatory System 1.21 1.06 – 1.38 0.00575 233 2328 all phecode
426.8 Other cardiac conduction disorders Circulatory System 1.14 0.87 – 1.5 0.342 60 600 all phecode
426.9 Cardiac pacemaker/device in situ Circulatory System 1.14 1.1 – 1.19 2.91e-10 2475 24774 all phecode
426.91 Cardiac pacemaker in situ Circulatory System 1.13 1.08 – 1.18 5.1e-08 2274 22762 all phecode
427 Cardiac dysrhythmias Circulatory System 1.1 1.08 – 1.11 6.21e-40 24207 206016 all phecode
427.1 Paroxysmal tachycardia, unspecified Circulatory System 1.11 1.07 – 1.15 1.19e-08 3199 32017 all phecode
427.11 Paroxysmal supraventricular tachycardia Circulatory System 1.12 1.07 – 1.17 3.61e-07 2344 23474 all phecode
427.12 Paroxysmal ventricular tachycardia Circulatory System 1.11 1.04 – 1.19 0.00171 936 9365 all phecode
427.2 Atrial fibrillation and flutter Circulatory System 1.09 1.07 – 1.11 3.35e-24 14628 133501 all phecode
427.3 Other specified cardiac dysrhythmias Circulatory System 1.06 1.02 – 1.1 0.00213 3228 32281 all phecode
427.4 Cardiac arrest and ventricular fibrillation Circulatory System 1.21 1.14 – 1.29 3.58e-10 1193 11915 all phecode
427.41 Ventricular fibrillation and flutter Circulatory System 1.19 1.06 – 1.33 0.00266 344 3437 all phecode
427.42 Cardiac arrest Circulatory System 1.23 1.15 – 1.31 9.69e-10 990 9890 all phecode
427.5 Arrhythmia (cardiac) NOS Circulatory System 1.16 1.08 – 1.24 1.53e-05 952 9541 all phecode
427.6 Premature beats Circulatory System 1.03 0.946 – 1.13 0.457 535 5358 all phecode
427.61 Supraventricular premature beats Circulatory System 1.04 0.866 – 1.25 0.677 117 1168 all phecode
427.7 Tachycardia NOS Circulatory System 1.16 1.11 – 1.21 4.73e-11 2185 21865 all phecode
427.8 Sinoatrial node dysfunction (Bradycardia) Circulatory System 1.11 1 – 1.23 0.0418 402 4029 all phecode
427.9 Palpitations Circulatory System 1.07 1.04 – 1.11 5.04e-05 3811 38105 all phecode
428 Congestive heart failure; nonhypertensive Circulatory System 1.22 1.18 – 1.25 6.9e-44 5605 56018 all phecode
428.1 Congestive heart failure (CHF) NOS Circulatory System 1.26 1.2 – 1.32 1.07e-23 2111 21108 all phecode
428.2 Heart failure NOS Circulatory System 1.21 1.18 – 1.25 1.57e-34 4455 44524 all phecode
429
Ill-defined descriptions and complications of
Ill-defined descriptions and complications of heart disease
 Circulatory System 1.08 1 – 1.17 0.0457 716 7168 all phecode
429.1 Heart transplant/surgery Circulatory System 1.45 1.12 – 1.88 0.00501 64 639 all phecode
429.2 Abnormal function study of cardiovascular system Circulatory System 1.06 0.967 – 1.16 0.217 522 5211 all phecode
429.3 Symptoms involving cardiovascular system Circulatory System 1.17 1.01 – 1.35 0.0377 196 1978 all phecode
430 Intracranial hemorrhage Circulatory System 1.16 1.11 – 1.22 8.63e-10 1883 18825 all phecode
430.1 Subarachnoid hemorrhage Circulatory System 1.24 1.15 – 1.33 7.89e-09 836 8353 all phecode
430.2 Intracerebral hemorrhage Circulatory System 1.13 1.05 – 1.22 0.00152 765 7656 all phecode
430.3 Subdural hemorrhage Circulatory System 1.02 0.902 – 1.16 0.729 267 2667 all phecode
433 Cerebrovascular disease Circulatory System 1.16 1.13 – 1.18 5.16e-38 8749 87456 all phecode
433.1 Occlusion and stenosis of precerebral arteries Circulatory System 1.37 1.29 – 1.45 9.85e-24 1185 11825 all phecode
433.12 Cerebral atherosclerosis Circulatory System 1.14 0.995 – 1.31 0.0585 227 2267 all phecode
433.2 Occlusion of cerebral arteries Circulatory System 1.14 1.1 – 1.17 3.59e-15 4233 42320 all phecode
433.21
Cerebral artery occlusion, with cerebral
Cerebral artery occlusion, with cerebral infarction
 Circulatory System 1.13 1.08 – 1.19 8.69e-07 1680 16794 all phecode
433.3 Cerebral ischemia Circulatory System 1.14 1.09 – 1.18 4.89e-11 2895 28989 all phecode
433.31 Transient cerebral ischemia Circulatory System 1.12 1.07 – 1.17 1.47e-06 2135 21379 all phecode
433.5 Cerebral aneurysm Circulatory System 1.31 1.18 – 1.46 4.89e-07 394 3939 all phecode
433.8 Late effects of cerebrovascular disease Circulatory System 1.19 1.13 – 1.27 2.09e-09 1279 12783 all phecode
440 Atherosclerosis Circulatory System 1.6 1.51 – 1.69 7.75e-57 1380 13822 all phecode
440.1 Atherosclerosis of renal artery Circulatory System 1.53 1.25 – 1.88 4.13e-05 113 1129 all phecode
440.2 Atherosclerosis of the extremities Circulatory System 1.78 1.65 – 1.92 5.1e-48 805 8070 all phecode
440.9 Atherosclerosis of aorta Circulatory System 1.68 1.48 – 1.91 1.12e-15 287 2867 all phecode
441 Vascular insufficiency of intestine Circulatory System 1.2 1.1 – 1.3 3.63e-05 614 6154 all phecode
441.1 Acute vascular insufficiency of intestine Circulatory System 1.15 1.02 – 1.3 0.0268 283 2827 all phecode
442 Other aneurysm Circulatory System 1.27 1.21 – 1.33 1.87e-22 1892 18959 all phecode
442.1 Aortic aneurysm Circulatory System 1.31 1.24 – 1.39 1.58e-22 1458 14625 all phecode
442.11 Abdominal aortic aneurysm Circulatory System 1.53 1.43 – 1.64 6.58e-33 931 9341 all phecode
442.2 Aneurysm of iliac artery Circulatory System 1.45 1.18 – 1.78 0.000452 102 1019 all phecode
442.3 Aneurysm of artery of lower extremity Circulatory System 1.27 1.08 – 1.5 0.00388 169 1696 all phecode
442.4 Arterial dissection Circulatory System 1.05 0.786 – 1.39 0.756 54 549 all phecode
442.8 Aneurysm of other specified artery Circulatory System 0.988 0.851 – 1.15 0.872 203 2028 all phecode
443 Peripheral vascular disease Circulatory System 1.4 1.35 – 1.45 3.7e-86 3921 39273 all phecode
443.1 Raynaud's syndrome Circulatory System 1.18 1.11 – 1.26 1.2e-07 1145 11438 all phecode
443.7
Peripheral angiopathy in diseases classified
Peripheral angiopathy in diseases classified elsewhere
 Circulatory System 1.2 1.08 – 1.33 0.000574 384 3878 all phecode
443.8 Other specified peripheral vascular diseases Circulatory System 1.43 1.38 – 1.48 8.88e-91 3686 36906 all phecode
443.9 Peripheral vascular disease, unspecified Circulatory System 1.56 1.49 – 1.62 7.73e-95 2579 25846 all phecode
444 Arterial embolism and thrombosis Circulatory System 1.56 1.46 – 1.68 4.02e-36 922 9251 all phecode
444.1
Arterial embolism and thrombosis of lower
Arterial embolism and thrombosis of lower extremity artery
 Circulatory System 1.66 1.52 – 1.82 2.83e-28 554 5552 all phecode
446 Polyarteritis nodosa and allied conditions Circulatory System 1.08 1 – 1.16 0.044 822 8226 all phecode
446.4 Wegener's granulomatosis Circulatory System 1.1 0.947 – 1.27 0.215 188 1878 all phecode
446.5 Giant cell arteritis Circulatory System 1.11 0.996 – 1.23 0.0596 388 3879 all phecode
446.9 Arteritis NOS Circulatory System 1.01 0.881 – 1.16 0.888 239 2400 all phecode
447 Other disorders of arteries and arterioles Circulatory System 1.51 1.43 – 1.6 7.14e-44 1327 13316 all phecode
447.1 Stricture of artery Circulatory System 1.67 1.55 – 1.8 6.25e-43 868 8712 all phecode
448 Disease of capillaries Circulatory System 1.2 1.01 – 1.43 0.038 142 1420 all phecode
450 Noninfectious disorders of lymphatic channels Circulatory System 1.14 1.06 – 1.24 0.000854 704 7034 all phecode
451 Phlebitis and thrombophlebitis Circulatory System 1.05 1.02 – 1.09 0.00148 3955 39683 all phecode
451.2
Phlebitis and thrombophlebitis of lower
Phlebitis and thrombophlebitis of lower extremities
 Circulatory System 1.05 1.01 – 1.09 0.00537 3683 36977 all phecode
452 Other venous embolism and thrombosis Circulatory System 1.07 0.977 – 1.16 0.151 564 5645 all phecode
454 Varicose veins Circulatory System 1.06 1.04 – 1.08 2.58e-09 11180 112047 all phecode
454.1 Varicose veins of lower extremity Circulatory System 1.06 1.04 – 1.09 3.81e-10 11503 115272 all phecode
454.11 Varicose veins of lower extremity, symptomtic Circulatory System 1.11 1.02 – 1.21 0.0132 624 6325 all phecode
455 Hemorrhoids Circulatory System 1.07 1.05 – 1.08 3.96e-20 23452 234585 all phecode
456 Chronic venous insufficiency [CVI] Circulatory System 1.08 0.933 – 1.26 0.291 184 1868 all phecode
457
Encounter for long-term (current) use of
Encounter for long-term (current) use of anticoagulants, antithrombotics, aspirin
 Circulatory System 0.824 0.673 – 1.01 0.0604 97 967 all phecode
458 Hypotension Circulatory System 1.11 1.08 – 1.14 5.78e-13 5769 57772 all phecode
458.1 Orthostatic hypotension Circulatory System 1.05 0.995 – 1.11 0.0729 1335 13376 all phecode
458.2 Iatrogenic hypotension Circulatory System 1.12 0.981 – 1.28 0.0926 235 2348 all phecode
458.9 Hypotension NOS Circulatory System 1.13 1.09 – 1.17 2.69e-11 3494 35005 all phecode
459 Other disorders of circulatory system Circulatory System 1.13 1.12 – 1.15 2.37e-52 16268 160790 all phecode
459.1 Hemorrhage NOS Circulatory System 1.15 0.964 – 1.36 0.123 142 1420 all phecode
459.9 Circulatory disease NEC Circulatory System 1.13 1.12 – 1.15 2.83e-51 16103 159422 all phecode
464 Acute sinusitis Respiratory 1.23 1.06 – 1.43 0.00732 196 1957 all phecode
465
Acute upper respiratory infections of multiple
Acute upper respiratory infections of multiple or unspecified sites
 Respiratory 1.07 1.02 – 1.11 0.00433 2283 22827 all phecode
465.2 Acute pharyngitis Respiratory 1.05 0.981 – 1.13 0.15 835 8348 all phecode
465.4 Acute laryngitis and tracheitis Respiratory 1.07 0.903 – 1.26 0.443 165 1649 all phecode
470 Septal Deviations/Turbinate Hypertrophy Respiratory 1.08 1.05 – 1.11 5.29e-07 4654 46553 all phecode
471 Nasal polyps Respiratory 1.05 1.01 – 1.09 0.0062 3297 32973 all phecode
472 Chronic pharyngitis and nasopharyngitis Respiratory 0.995 0.93 – 1.06 0.88 960 9594 all phecode
473 Diseases of the larynx and vocal cords Respiratory 1.25 1.2 – 1.31 6.29e-27 2554 25548 all phecode
473.1 Chronic laryngitis Respiratory 1.41 1.14 – 1.74 0.00141 104 1038 all phecode
473.3 Paralysis/spasm of vocal cords or larynx Respiratory 1.02 0.897 – 1.16 0.774 264 2647 all phecode
473.4 Voice disturbance Respiratory 1.2 1.12 – 1.28 2.18e-08 1080 10789 all phecode
474 Acute and chronic tonsillitis Respiratory 1.1 1.05 – 1.16 9.49e-05 1772 17710 all phecode
474.1 Acute tonsillitis Respiratory 1.09 0.998 – 1.19 0.0542 549 5486 all phecode
474.2 Chronic tonsillitis and adenoiditis Respiratory 1.08 1.01 – 1.15 0.0218 1122 11199 all phecode
475 Chronic sinusitis Respiratory 1.11 1.06 – 1.15 1.28e-06 2589 25882 all phecode
476 Allergic rhinitis Respiratory 0.897 0.842 – 0.957 0.000926 1055 10563 all phecode
477 Epistaxis or throat hemorrhage Respiratory 1.08 1.04 – 1.13 0.00016 2447 24452 all phecode
478 Throat pain Respiratory 1.09 0.986 – 1.21 0.0894 377 3789 all phecode
479 Other upper respiratory disease Respiratory 1.11 1.08 – 1.15 1.07e-10 4074 40737 all phecode
480 Pneumonia Respiratory 1.22 1.2 – 1.25 4.17e-81 10336 103397 all phecode
480.1 Bacterial pneumonia Respiratory 1.22 1.19 – 1.25 2.92e-54 6637 66410 all phecode
480.11 Pneumococcal pneumonia Respiratory 1.24 1.2 – 1.27 6.13e-53 5883 58863 all phecode
480.12 Pseudomonal pneumonia Respiratory 1.59 1.27 – 2 4.62e-05 93 929 all phecode
480.2 Viral pneumonia Respiratory 1.04 0.814 – 1.33 0.758 72 720 all phecode
480.3 Pneumonia due to fungus (mycoses) Respiratory 1.2 0.98 – 1.47 0.0774 99 989 all phecode
480.5 Bronchopneumonia and lung abscess Respiratory 1.27 1.18 – 1.36 2.7e-10 794 7951 all phecode
481 Influenza Respiratory 1.22 1.09 – 1.37 0.000655 328 3278 all phecode
483 Acute bronchitis and bronchiolitis Respiratory 1.32 1.13 – 1.53 0.000387 193 1930 all phecode
495 Asthma Respiratory 1.11 1.1 – 1.13 3.5e-58 25689 250406 all phecode
495.2 Asthma with exacerbation Respiratory 1.26 1.11 – 1.43 0.000416 250 2510 all phecode
496 Chronic airway obstruction Respiratory 1.6 1.56 – 1.63 4.59e-413 10424 101546 all phecode
496.1 Emphysema Respiratory 1.78 1.69 – 1.87 1.18e-102 1743 17438 all phecode
496.2 Chronic bronchitis Respiratory 1.82 1.75 – 1.9 1.34e-184 2947 29498 all phecode
496.21 Obstructive chronic bronchitis Respiratory 1.86 1.78 – 1.94 6.29e-180 2706 27081 all phecode
496.3 Bronchiectasis Respiratory 1.17 1.11 – 1.23 1.95e-10 1885 18859 all phecode
497 Bronchitis Respiratory 1.21 1.12 – 1.32 4.71e-06 626 6267 all phecode
500 Lung disease due to external agents Respiratory 1.46 1.32 – 1.62 1.01e-12 412 4099 all phecode
500.1 Extrinsic allergic alveolitis Respiratory 1.22 0.968 – 1.53 0.0924 79 784 all phecode
500.2 Pneumoconiosis Respiratory 1.61 1.4 – 1.85 1.98e-11 243 2409 all phecode
501 Pneumonitis due to inhalation of food or vomitus Respiratory 1.18 1.09 – 1.28 6.58e-05 656 6557 all phecode
502 Postinflammatory pulmonary fibrosis Respiratory 1.27 1.19 – 1.36 5.49e-12 917 9193 all phecode
503 Pulmonary congestion and hypostasis Respiratory 1.35 1.23 – 1.48 2.54e-10 508 5079 all phecode
504 Other alveolar and parietoalveolar pneumonopathy Respiratory 1.32 1.18 – 1.48 1.6e-06 328 3280 all phecode
505 Other pulmonary inflamation or edema Respiratory 0.963 0.737 – 1.26 0.781 61 610 all phecode
506 Empyema and pneumothorax Respiratory 1.29 1.22 – 1.37 2.27e-16 1133 11362 all phecode
507 Pleurisy; pleural effusion Respiratory 1.17 1.14 – 1.2 3.81e-32 6419 64252 all phecode
508
Pulmonary collapse; interstitial and
Pulmonary collapse; interstitial and compensatory emphysema
 Respiratory 1.18 1.12 – 1.23 7.47e-12 1996 19947 all phecode
509 Respiratory failure, insufficiency, arrest Respiratory 1.31 1.26 – 1.37 1.06e-38 2599 26031 all phecode
509.1 Respiratory failure Respiratory 1.35 1.29 – 1.41 6.23e-37 2068 20708 all phecode
509.2 Respiratory insufficiency Respiratory 1.36 1.3 – 1.43 2.02e-34 1806 18106 all phecode
509.5 Respiratory arrest Respiratory 1.09 0.917 – 1.29 0.338 143 1429 all phecode
509.8
Dependence on respirator [Ventilator] or
Dependence on respirator [Ventilator] or supplemental oxygen
 Respiratory 1.28 1.16 – 1.43 3.1e-06 386 3863 all phecode
510 Other diseases of lung Respiratory 1.27 1.18 – 1.37 3.55e-10 755 7554 all phecode
512 Other symptoms of respiratory system Respiratory 1.17 1.14 – 1.19 1.62e-43 9031 90349 all phecode
512.1 Wheezing Respiratory 1.18 1.02 – 1.35 0.0214 220 2196 all phecode
512.2 Painful respiration Respiratory 1.22 1.06 – 1.41 0.00706 207 2075 all phecode
512.7 Shortness of breath Respiratory 1.2 1.17 – 1.24 1.25e-40 5842 58498 all phecode
512.8 Cough Respiratory 1.13 1.09 – 1.18 5.67e-10 2866 28642 all phecode
512.9 Other dyspnea Respiratory 1.13 1.05 – 1.21 0.000523 914 9124 all phecode
513 Respiratory abnormalities Respiratory 1.09 1 – 1.19 0.0394 611 6112 all phecode
513.3 Hypoventilation Respiratory 1.19 0.953 – 1.5 0.123 83 830 all phecode
513.4 Hyperventilation Respiratory 1.04 0.916 – 1.18 0.561 278 2778 all phecode
513.8 Disorders of diaphragm Respiratory 1.12 0.954 – 1.33 0.163 153 1538 all phecode
514 Abnormal findings examination of lungs Respiratory 1.34 1.28 – 1.4 1.68e-42 2465 24673 all phecode
516 Abnormal sputum Respiratory 1.35 1.29 – 1.41 3.29e-38 2132 21335 all phecode
516.1 Hemoptysis Respiratory 1.35 1.29 – 1.42 1.62e-37 2073 20745 all phecode
519
Other diseases of respiratory system, not
Other diseases of respiratory system, not elsewhere classified
 Respiratory 1.16 1.14 – 1.19 2.86e-43 9366 93681 all phecode
519.2 Respiratory complications Respiratory 1.33 1.19 – 1.5 1.08e-06 327 3279 all phecode
519.8 Other diseases of respiratory system, NEC Respiratory 1.17 1.14 – 1.19 5.44e-43 8853 88522 all phecode
519.9
Symptoms involving respiratory system and other
Symptoms involving respiratory system and other chest symptoms
 Respiratory 1.01 0.892 – 1.13 0.925 303 3049 all phecode
520 Disorders of tooth development Digestive 1.02 0.978 – 1.07 0.318 2038 20354 all phecode
520.1 Hereditary disturbances in tooth structure Digestive 1.2 0.897 – 1.6 0.223 53 530 all phecode
520.2 Disturbances in tooth eruption Digestive 0.989 0.947 – 1.03 0.596 2356 23539 all phecode
521 Diseases of hard tissues of teeth Digestive 1.1 1.06 – 1.14 1.62e-06 3016 30245 all phecode
521.1 Dental caries Digestive 1.1 1.06 – 1.14 7.68e-07 3026 30353 all phecode
522 Diseases of pulp and periapical tissues Digestive 1.12 1.07 – 1.18 7.5e-06 1774 17750 all phecode
522.5 Periapical abscess Digestive 1.12 1.06 – 1.19 0.000175 1172 11731 all phecode
523 Gingival and periodontal diseases Digestive 1.1 1.04 – 1.15 0.00044 1681 16812 all phecode
523.1 Gingivitis Digestive 0.982 0.807 – 1.19 0.857 113 1127 all phecode
523.3 Periodontitis (acute or chronic) Digestive 1.09 1.02 – 1.16 0.00706 1165 11650 all phecode
523.31 Acute periodontitis Digestive 1.1 1.01 – 1.19 0.0231 666 6667 all phecode
523.32 Chronic periodontitis Digestive 1.04 0.948 – 1.13 0.428 560 5594 all phecode
524 Dentofacial anomalies, including malocclusion Digestive 1.04 0.93 – 1.17 0.482 331 3307 all phecode
524.3 Anomalies of tooth position/malocclusion Digestive 0.984 0.874 – 1.11 0.794 305 3046 all phecode
525
Other diseases of the teeth and supporting
Other diseases of the teeth and supporting structures
 Digestive 1.09 1.05 – 1.13 3.03e-05 2668 26728 all phecode
525.2 Atrophy of edentulous alveolar ridge Digestive 1.15 0.901 – 1.46 0.266 72 720 all phecode
526 Diseases of the jaws Digestive 1.08 1.01 – 1.16 0.0199 928 9279 all phecode
526.1 Cysts of the jaws Digestive 1.09 0.975 – 1.23 0.125 329 3289 all phecode
526.3 Anomalies of jaw size/symmetry Digestive 0.9 0.7 – 1.16 0.412 61 610 all phecode
526.4 Temporomandibular joint disorders Digestive 1.13 0.982 – 1.29 0.0887 240 2406 all phecode
526.41 Temporomandibular joint disorder, unspecified Digestive 1.14 0.989 – 1.31 0.0719 233 2336 all phecode
526.5 Inflammatory conditions of jaw Digestive 1.12 0.926 – 1.36 0.238 110 1098 all phecode
526.9 Jaw disease NOS Digestive 1.06 0.929 – 1.21 0.378 233 2329 all phecode
527 Diseases of the salivary glands Digestive 1.18 1.09 – 1.28 3.26e-05 694 6943 all phecode
527.1 Hypertrophy of salivary gland Digestive 1.13 0.899 – 1.42 0.298 84 838 all phecode
527.2 Sialoadenitis Digestive 1.16 1.04 – 1.29 0.00866 365 3656 all phecode
527.7 Disturbance of salivary secretion Digestive 1.1 0.852 – 1.43 0.452 62 619 all phecode
527.8 Other specified diseases of the salivary glands Digestive 1.39 1.16 – 1.68 0.000503 120 1200 all phecode
528
Diseases of the oral soft tissues, excluding
Diseases of the oral soft tissues, excluding lesions specific for gingiva and tongue
 Digestive 1.13 1.1 – 1.17 2.46e-13 3873 38741 all phecode
528.1 Stomatitis and mucositis Digestive 1.05 0.958 – 1.16 0.283 468 4675 all phecode
528.11 Stomatitis and mucositis (ulcerative) Digestive 1.08 0.971 – 1.19 0.161 389 3884 all phecode
528.12 Oral aphthae Digestive 0.926 0.74 – 1.16 0.504 84 840 all phecode
528.3 Cellulitis and abscess of oral soft tissues Digestive 1.21 1.04 – 1.42 0.015 179 1790 all phecode
528.4 Cysts of oral soft tissues Digestive 1.25 1.03 – 1.52 0.0267 122 1219 all phecode
528.41 Cyst of the salivary gland Digestive 1.12 0.899 – 1.39 0.319 94 940 all phecode
528.5 Diseases of lips Digestive 1.11 1.02 – 1.2 0.011 681 6813 all phecode
528.6 Leukoplakia of oral mucosa Digestive 1.22 1.09 – 1.38 0.000591 308 3079 all phecode
528.7 Sialolithiasis Digestive 1.28 1.13 – 1.44 4.81e-05 314 3138 all phecode
529 Diseases and other conditions of the tongue Digestive 1.09 1.03 – 1.16 0.00429 1232 12312 all phecode
529.1 Glossitis Digestive 1.1 0.979 – 1.24 0.106 299 2986 all phecode
530 Diseases of esophagus Digestive 1.12 1.11 – 1.14 9.03e-86 33453 279172 all phecode
530.1 Esophagitis, GERD and related diseases Digestive 1.12 1.11 – 1.13 2.69e-79 31253 272429 all phecode
530.11 GERD Digestive 1.12 1.1 – 1.13 5.93e-56 22633 225879 all phecode
530.12 Ulcer of esophagus Digestive 1.12 1.09 – 1.16 2.02e-15 5203 52068 all phecode
530.14 Reflux esophagitis Digestive 1.11 1.09 – 1.14 4.52e-25 10444 104493 all phecode
530.2 Esophageal bleeding (varices/hemorrhage) Digestive 1.15 1.09 – 1.21 6.01e-08 1681 16808 all phecode
530.3 Stricture and stenosis of esophagus Digestive 1.12 1.07 – 1.18 1.71e-06 1869 18684 all phecode
530.5 Disorders of esophageal motility Digestive 1.09 1 – 1.18 0.0467 635 6365 all phecode
530.6 Diverticulum of esophagus, acquired Digestive 1.18 1 – 1.4 0.0497 153 1527 all phecode
530.7 Gastroesophageal laceration-hemorrhage syndrome Digestive 1.17 1.04 – 1.31 0.00702 341 3416 all phecode
530.9 Heartburn Digestive 1.09 1.04 – 1.14 0.000164 2087 20881 all phecode
531 Peptic ulcer (excl. esophageal) Digestive 1.19 1.16 – 1.22 8.51e-42 7103 71066 all phecode
531.1 Hemorrhage from gastrointestinal ulcer Digestive 1.12 1.03 – 1.21 0.00752 637 6374 all phecode
531.2 Gastric ulcer Digestive 1.18 1.15 – 1.22 1.9e-24 4091 40941 all phecode
531.3 Duodenal ulcer Digestive 1.21 1.16 – 1.25 4.11e-22 2999 30005 all phecode
531.4 Peptic ulcer, site unspecified Digestive 1.24 1.12 – 1.38 2.58e-05 427 4268 all phecode
532 Dysphagia Digestive 1.1 1.07 – 1.13 7.46e-13 6427 64329 all phecode
535 Gastritis and duodenitis Digestive 1.14 1.12 – 1.15 2.56e-88 28078 261548 all phecode
535.1 Acute gastritis Digestive 1.13 1.07 – 1.2 5.63e-05 1183 11833 all phecode
535.2 Atrophic gastritis Digestive 1.04 0.936 – 1.16 0.447 370 3687 all phecode
535.6 Duodenitis Digestive 1.2 1.18 – 1.23 3.99e-52 7592 75928 all phecode
535.8 Other specified gastritis Digestive 1.12 1.09 – 1.14 2.29e-20 8071 80763 all phecode
535.9 Gastritis and duodenitis, NOS Digestive 1.13 0.937 – 1.36 0.202 120 1191 all phecode
536.8
Dyspepsia and other specified disorders of
Dyspepsia and other specified disorders of function of stomach
 Digestive 1.08 0.958 – 1.23 0.199 259 2576 all phecode
537 Other disorders of stomach and duodenum Digestive 1.15 1.11 – 1.19 1.81e-14 3391 33907 all phecode
540 Appendiceal conditions Digestive 1.05 1.01 – 1.09 0.0152 3088 30890 all phecode
540.1 Appendicitis Digestive 1.05 1.01 – 1.09 0.0153 2895 28963 all phecode
540.11 Acute appendicitis Digestive 1.04 1 – 1.08 0.0503 2601 26019 all phecode
550 Abdominal hernia Digestive 1.07 1.06 – 1.08 1.57e-37 45429 282640 all phecode
550.1 Inguinal hernia Digestive 1 0.986 – 1.02 0.777 15794 123247 all phecode
550.2 Diaphragmatic hernia Digestive 1.09 1.07 – 1.1 6.15e-37 26494 238953 all phecode
550.3 Femoral hernia Digestive 1.08 0.996 – 1.18 0.0634 651 6504 all phecode
550.4 Umbilical hernia Digestive 1.13 1.09 – 1.17 1.32e-12 3705 37072 all phecode
550.5 Ventral hernia Digestive 1.19 1.15 – 1.23 1.6e-21 3435 34338 all phecode
555
Inflammatory bowel disease and other
Inflammatory bowel disease and other gastroenteritis and colitis
 Digestive 1.16 1.13 – 1.2 5.47e-21 4444 44442 all phecode
555.1 Regional enteritis Digestive 1.2 1.14 – 1.26 6.21e-13 1734 17340 all phecode
555.2 Ulcerative colitis Digestive 1.13 1.09 – 1.17 1.69e-10 3178 31786 all phecode
555.21 Ulcerative colitis (chronic) Digestive 1.2 1.09 – 1.31 1e-04 538 5382 all phecode
556 Ulceration of the lower GI tract Digestive 1.18 1.11 – 1.26 2.34e-07 1055 10592 all phecode
556.1 Ulceration of intestine Digestive 1.22 1.13 – 1.33 9.12e-07 670 6714 all phecode
557 Intestinal malabsorption (non-celiac) Digestive 1 0.892 – 1.13 0.953 299 2987 all phecode
557.1 Celiac disease Digestive 0.932 0.887 – 0.979 0.00474 1837 18388 all phecode
558 Noninfectious gastroenteritis Digestive 1.1 1.08 – 1.12 5.02e-29 15492 155105 all phecode
559 Ileostomy status Digestive 1.13 1.08 – 1.19 2.23e-06 1656 16541 all phecode
560 Intestinal obstruction without mention of hernia Digestive 1.07 1.04 – 1.11 5.64e-05 3936 39337 all phecode
560.1 Paralytic ileus Digestive 1.15 1.05 – 1.26 0.00186 523 5231 all phecode
560.2 Impaction of intestine Digestive 1.01 0.894 – 1.15 0.83 268 2671 all phecode
560.3 Peritoneal or intestinal adhesions Digestive 1.1 1.03 – 1.19 0.00722 832 8317 all phecode
560.4 Other intestinal obstruction Digestive 1.07 1.03 – 1.11 0.000152 3358 33550 all phecode
561 Symptoms involving digestive system Digestive 1.09 1.07 – 1.1 8.32e-22 15772 157686 all phecode
561.1 Diarrhea Digestive 1.14 1.03 – 1.25 0.0105 466 4653 all phecode
561.2 Flatulence Digestive 1.05 1 – 1.11 0.0497 1687 16859 all phecode
562 Diverticulosis and diverticulitis Digestive 1.12 1.1 – 1.13 1.43e-64 26714 211692 all phecode
562.1 Diverticulosis Digestive 1.12 1.1 – 1.13 1.72e-64 26672 211642 all phecode
563 Constipation Digestive 1.11 1.09 – 1.13 2.17e-23 10314 103140 all phecode
564 Functional digestive disorders Digestive 1.11 1.1 – 1.13 1.67e-48 21639 209949 all phecode
564.1 Irritable Bowel Syndrome Digestive 1.09 1.06 – 1.12 5.74e-09 5508 55117 all phecode
564.8
Abnormal findings on exam of gastrointestinal
Abnormal findings on exam of gastrointestinal tract/ abdominal area
 Digestive 1.1 1.05 – 1.16 0.000224 1645 16457 all phecode
564.9 Personal history of diseases of digestive system Digestive 1.13 1.11 – 1.15 5.02e-45 15186 151648 all phecode
565 Anal and rectal conditions Digestive 1.15 1.13 – 1.17 1.52e-54 14744 147535 all phecode
565.1 Anal and rectal polyp Digestive 1.21 1.18 – 1.24 2.24e-51 7351 73533 all phecode
567 Peritonitis and retroperitoneal infections Digestive 1.17 1.09 – 1.25 7.42e-06 929 9293 all phecode
568 Other disorders of peritoneum Digestive 1.12 1.08 – 1.16 3.95e-09 3262 32602 all phecode
568.1
Peritoneal adhesions (postoperative)
Peritoneal adhesions (postoperative) (postinfection)
 Digestive 1.11 1.07 – 1.16 1.73e-08 3101 30987 all phecode
569 Other disorders of intestine Digestive 1.1 1.07 – 1.14 1.3e-09 4192 41922 all phecode
569.1 Toxic gastroenteritis and colitis Digestive 1.01 0.848 – 1.19 0.945 148 1479 all phecode
569.2 Gastrointestinal complications Digestive 1.1 1.01 – 1.21 0.0363 486 4868 all phecode
571 Chronic liver disease and cirrhosis Digestive 1.23 1.18 – 1.28 1.66e-25 2957 29628 all phecode
571.5 Other chronic nonalcoholic liver disease Digestive 1.22 1.16 – 1.28 4.28e-14 1689 16917 all phecode
571.51 Cirrhosis of liver without mention of alcohol Digestive 1.02 0.842 – 1.23 0.869 113 1139 all phecode
571.6 Primary biliary cirrhosis Digestive 1.25 1.1 – 1.43 0.000845 257 2568 all phecode
571.8
Liver abscess and sequelae of chronic liver
Liver abscess and sequelae of chronic liver disease
 Digestive 1.22 1.14 – 1.31 3.11e-09 976 9804 all phecode
571.81 Portal hypertension Digestive 1.29 1.17 – 1.41 6.59e-08 528 5285 all phecode
572 Ascites (non malignant) Digestive 1.1 1.04 – 1.16 0.000498 1544 15454 all phecode
573 Other disorders of liver Digestive 1.06 1 – 1.11 0.0449 1496 14982 all phecode
573.2 Liver replaced by transplant Digestive 1.06 0.87 – 1.3 0.543 96 960 all phecode
573.3 Hepatomegaly Digestive 1.26 1.12 – 1.42 0.000169 297 2968 all phecode
573.5 Jaundice (not of newborn) Digestive 1.06 0.993 – 1.14 0.0782 896 8955 all phecode
573.7 Abnormal results of function study of liver Digestive 1.1 1.06 – 1.14 7.05e-08 3454 34597 all phecode
573.9 Abnormal serum enzyme levels Digestive 1.2 1.04 – 1.38 0.0134 209 2089 all phecode
574 Cholelithiasis and cholecystitis Digestive 1.09 1.07 – 1.11 1e-23 15607 156123 all phecode
574.1 Cholelithiasis Digestive 1.09 1.07 – 1.11 1.1e-19 13549 135537 all phecode
574.11 Cholelithiasis with acute cholecystitis Digestive 1.14 1.08 – 1.2 3.63e-06 1506 15072 all phecode
574.12 Cholelithiasis with other cholecystitis Digestive 1.08 1.05 – 1.11 4.43e-08 5429 54289 all phecode
574.2 Calculus of bile duct Digestive 1.13 1.08 – 1.17 1.19e-08 2620 26191 all phecode
574.3 Cholecystitis without cholelithiasis Digestive 1.12 1.08 – 1.17 7.47e-09 2748 27523 all phecode
575 Other biliary tract disease Digestive 1.09 1.06 – 1.13 1.84e-07 3867 38724 all phecode
575.1 Cholangitis Digestive 1.09 0.995 – 1.2 0.0635 495 4945 all phecode
575.2 Obstruction of bile duct Digestive 1.14 1.05 – 1.22 0.000769 774 7756 all phecode
575.6 Cholesterolosis of gallbladder Digestive 0.966 0.874 – 1.07 0.495 458 4577 all phecode
575.7 Other disorders of gallbladder Digestive 1.06 1.01 – 1.13 0.0301 1408 14107 all phecode
575.8 Other disorders of biliary tract Digestive 1.15 1.08 – 1.23 1.83e-05 1036 10367 all phecode
575.9
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of biliary tract
 Digestive 1.23 1.1 – 1.37 0.000254 348 3488 all phecode
577 Diseases of pancreas Digestive 1.13 1.08 – 1.17 6.69e-09 2668 26677 all phecode
577.1 Acute pancreatitis Digestive 1.13 1.08 – 1.19 1.28e-07 1996 19962 all phecode
577.2 Chronic pancreatitis Digestive 1.23 1.13 – 1.35 6.24e-06 515 5149 all phecode
577.3 Cyst and pseudocyst of pancreas Digestive 1.13 1.02 – 1.26 0.0217 365 3650 all phecode
578 Gastrointestinal hemorrhage Digestive 1.09 1.07 – 1.1 3.17e-29 20626 206278 all phecode
578.1 Hematemesis Digestive 1.24 1.18 – 1.3 1.87e-19 1958 19564 all phecode
578.2 Blood in stool Digestive 1.13 1.08 – 1.17 8.09e-09 2626 26283 all phecode
578.8 Hemorrhage of rectum and anus Digestive 1.07 1.06 – 1.09 8.47e-15 13073 130745 all phecode
578.9 Hemorrhage of gastrointestinal tract Digestive 1.09 1.06 – 1.12 7.91e-09 5275 52787 all phecode
579 Other symptoms involving abdomen and pelvis Digestive 1.08 1.02 – 1.13 0.00725 1548 15498 all phecode
579.2 Splenomegaly Digestive 1.1 0.997 – 1.22 0.0568 422 4246 all phecode
579.8 Nonspecific abnormal findings in stool contents Digestive 1.03 0.978 – 1.08 0.279 1654 16540 all phecode
580 Nephritis; nephrosis; renal sclerosis Genitourinary 1.11 1.05 – 1.17 0.000101 1531 15350 all phecode
580.1 Glomerulonephritis Genitourinary 1.11 1.04 – 1.18 0.00186 1052 10544 all phecode
580.11 Proliferative glomerulonephritis Genitourinary 1.05 0.833 – 1.32 0.68 74 738 all phecode
580.12 Non-proliferative glomerulonephritis Genitourinary 1.02 0.851 – 1.22 0.85 135 1360 all phecode
580.14 Chronic glomerulonephritis, NOS Genitourinary 1.12 1.05 – 1.21 0.00123 876 8769 all phecode
580.2
Nephrotic syndrome without mention of
Nephrotic syndrome without mention of glomerulonephritis
 Genitourinary 1.1 1 – 1.21 0.0433 468 4697 all phecode
580.3
Nephritis and nephropathy without mention of
Nephritis and nephropathy without mention of glomerulonephritis
 Genitourinary 1.19 1.04 – 1.36 0.0101 246 2460 all phecode
580.32
Nephritis and nephropathy with pathological
Nephritis and nephropathy with pathological lesion
 Genitourinary 1.16 1.01 – 1.32 0.0294 253 2529 all phecode
585 Renal failure Genitourinary 1.12 1.1 – 1.15 2.03e-20 6967 69751 all phecode
585.1 Acute renal failure Genitourinary 1.14 1.11 – 1.18 8.77e-18 4527 45305 all phecode
585.2 Renal failure NOS Genitourinary 1.09 1.04 – 1.15 0.00118 1460 14625 all phecode
585.3 Chronic renal failure [CKD] Genitourinary 1.14 1.1 – 1.19 1.82e-10 2644 26484 all phecode
585.31 Renal dialysis Genitourinary 1.14 1.04 – 1.26 0.00416 496 4955 all phecode
586 Other disorders of the kidney and ureters Genitourinary 1.1 1.06 – 1.13 4.87e-07 3355 33580 all phecode
586.1 Anatomical abnormatilies of kidney and ureters Genitourinary 1.11 0.961 – 1.27 0.158 208 2089 all phecode
586.11 Small kidney Genitourinary 1.13 0.973 – 1.32 0.107 179 1799 all phecode
586.2 Cyst of kidney, acquired Genitourinary 1.09 1.03 – 1.15 0.00491 1257 12582 all phecode
586.3 Vascular disorders of kidney/hypertrophy Genitourinary 1.1 0.878 – 1.39 0.397 80 799 all phecode
586.4 Stricture/obstruction of ureter Genitourinary 1.13 1.05 – 1.21 0.000698 910 9122 all phecode
587 Kidney replaced by transpant Genitourinary 1.04 0.93 – 1.16 0.516 368 3683 all phecode
588 Disorders resulting from impaired renal function Genitourinary 1.08 0.875 – 1.33 0.475 99 990 all phecode
589 Abnormal results of function study of kidney Genitourinary 1.17 0.97 – 1.4 0.103 116 1158 all phecode
590 Pyelonephritis Genitourinary 1.18 1.12 – 1.25 8.16e-09 1328 13285 all phecode
591 Urinary tract infection Genitourinary 1.08 1.06 – 1.1 5.24e-17 12400 123937 all phecode
592 Cystitis and urethritis Genitourinary 1.05 1.01 – 1.09 0.00728 2966 29661 all phecode
592.1 Cystitis Genitourinary 1.06 1.02 – 1.1 0.0064 2904 29035 all phecode
592.11 Acute cystitis Genitourinary 1.09 0.921 – 1.3 0.305 138 1372 all phecode
592.12 Chronic cystitis Genitourinary 1.07 0.997 – 1.15 0.0608 889 8890 all phecode
592.13 Chronic interstitial cystitis Genitourinary 0.83 0.726 – 0.949 0.00631 249 2486 all phecode
592.2 Urethritis and urethral syndrome Genitourinary 0.979 0.837 – 1.15 0.796 165 1662 all phecode
593 Hematuria Genitourinary 1.07 1.05 – 1.09 3.4e-16 16068 160204 all phecode
594 Urinary calculus Genitourinary 1.05 1.02 – 1.07 0.000499 6376 63761 all phecode
594.1 Calculus of kidney Genitourinary 1.06 1.02 – 1.1 0.00371 3175 31757 all phecode
594.2 Calculus of lower urinary tract Genitourinary 1 0.929 – 1.08 0.998 776 7764 all phecode
594.3 Calculus of ureter Genitourinary 1.06 1.02 – 1.11 0.00559 2401 24024 all phecode
594.8 Renal colic Genitourinary 1.04 0.994 – 1.09 0.0851 2050 20500 all phecode
595 Hydronephrosis Genitourinary 1.05 1.01 – 1.1 0.0287 1936 19395 all phecode
596 Other disorders of bladder Genitourinary 1.03 1.01 – 1.05 0.00425 9771 97778 all phecode
596.1 Bladder neck obstruction Genitourinary 0.942 0.9 – 0.986 0.0102 1969 19690 all phecode
596.5 Functional disorders of bladder Genitourinary 1.09 1.04 – 1.15 0.000919 1658 16572 all phecode
597 Other disorders of urethra and urinary tract Genitourinary 1.02 0.984 – 1.05 0.325 3913 39135 all phecode
597.1 Urethral stricture (not specified as infectious) Genitourinary 1.02 0.982 – 1.06 0.322 3317 33137 all phecode
597.2 Urinary complications NEC Genitourinary 1.21 0.955 – 1.53 0.114 78 778 all phecode
598 Abnormal findings on examination of urine Genitourinary 1.06 1.02 – 1.09 0.00174 3528 35302 all phecode
598.9
Other nonspecific findings on examination of
Other nonspecific findings on examination of urine
 Genitourinary 1.04 0.922 – 1.17 0.521 304 3035 all phecode
599 Other symptoms/disorders or the urinary system Genitourinary 1.07 1.05 – 1.09 1.69e-17 18428 184311 all phecode
599.1 Urinary obstruction Genitourinary 0.981 0.841 – 1.14 0.809 166 1670 all phecode
599.2 Retention of urine Genitourinary 1.04 1.01 – 1.06 0.00323 6718 67168 all phecode
599.3 Dysuria Genitourinary 1.11 1.04 – 1.18 0.000784 1196 11967 all phecode
599.4 Urinary incontinence Genitourinary 1.09 1.07 – 1.12 4.14e-14 8748 87477 all phecode
599.5 Frequency of urination and polyuria Genitourinary 1.06 1.02 – 1.09 0.000799 4018 40144 all phecode
599.6 Oliguria and anuria Genitourinary 1.02 0.841 – 1.24 0.821 105 1059 all phecode
599.8 Other symptoms involving urinary system Genitourinary 1.16 0.899 – 1.51 0.25 62 620 all phecode
599.9 Other abnormality of urination Genitourinary 1.03 0.982 – 1.08 0.237 1913 19151 all phecode
600 Hyperplasia of prostate Genitourinary 0.997 0.978 – 1.02 0.77 11093 87892 all phecode
601 Inflammatory diseases of prostate Genitourinary 0.962 0.92 – 1.01 0.0904 2081 20818 all phecode
601.1 Prostatitis Genitourinary 0.934 0.887 – 0.983 0.00864 1563 15644 all phecode
601.11 Acute prostatitis Genitourinary 0.876 0.767 – 1 0.0508 234 2358 all phecode
601.12 Chronic prostatitis Genitourinary 0.904 0.846 – 0.966 0.00274 910 9089 all phecode
601.3 Orchitis and epididymitis Genitourinary 1.3 1 – 1.69 0.0473 59 588 all phecode
601.4 Balanoposthitis Genitourinary 1.02 0.907 – 1.15 0.739 287 2864 all phecode
601.8
Other inflammatory disorders of male genital
Other inflammatory disorders of male genital organs
 Genitourinary 1.07 0.946 – 1.2 0.291 303 3019 all phecode
602 Other disorders of prostate Genitourinary 0.997 0.944 – 1.05 0.901 1341 13408 all phecode
603 Other disorders of testis Genitourinary 1.05 1.01 – 1.1 0.0217 2150 21512 all phecode
603.1 Hydrocele Genitourinary 1.04 0.982 – 1.1 0.192 1339 13402 all phecode
604 Disorders of penis Genitourinary 1.02 0.985 – 1.06 0.255 3280 32779 all phecode
604.1 Redundant prepuce and phimosis/BXO Genitourinary 1.03 0.99 – 1.07 0.147 2719 27172 all phecode
605 Erectile dysfunction [ED] Genitourinary 1.13 1 – 1.28 0.0467 278 2800 all phecode
608 Other disorders of male genital organs Genitourinary 1.04 1 – 1.08 0.0342 2822 28236 all phecode
609 Male infertility and abnormal spermatozoa Genitourinary 1.11 0.97 – 1.28 0.126 214 2138 all phecode
609.1 Infertility, male Genitourinary 1.1 0.842 – 1.44 0.477 63 638 all phecode
609.2 Abnormal spermatozoa Genitourinary 1.12 0.96 – 1.31 0.15 169 1698 all phecode
610 Benign mammary dysplasias Genitourinary 1.03 0.99 – 1.08 0.131 2482 24809 all phecode
610.1 Cystic mastopathy Genitourinary 0.999 0.932 – 1.07 0.986 925 9250 all phecode
610.2 Fibroadenosis of breast Genitourinary 1.02 0.904 – 1.16 0.727 306 3057 all phecode
610.3 Fibrosclerosis of breast Genitourinary 1.09 0.964 – 1.23 0.17 302 3018 all phecode
610.4 Benign neoplasm of breast Genitourinary 1.03 0.972 – 1.09 0.33 1388 13865 all phecode
610.8 Other specified benign mammary dysplasias Genitourinary 1.07 0.983 – 1.16 0.12 696 6954 all phecode
611 Abnormal findings on mammogram or breast exam Genitourinary 1.05 0.995 – 1.11 0.0777 1574 15731 all phecode
611.1 Abnormal mammogram Genitourinary 1.17 0.891 – 1.52 0.265 57 569 all phecode
611.3 Lump or mass in breast Genitourinary 1.05 0.993 – 1.11 0.091 1522 15213 all phecode
612
Breast conditions, congenital or relating to
Breast conditions, congenital or relating to hormones
 Genitourinary 1.04 0.974 – 1.12 0.221 887 8871 all phecode
612.2 Hypertrophy of breast (Gynecomastia) Genitourinary 1.05 0.975 – 1.13 0.201 849 8490 all phecode
612.3 Congenital anomalies of breast Genitourinary 1.07 0.834 – 1.37 0.599 72 719 all phecode
613 Other nonmalignant breast conditions Genitourinary 1.07 1.01 – 1.12 0.0173 1651 16519 all phecode
613.1 Inflammatory disease of breast Genitourinary 1.1 1.02 – 1.19 0.0167 720 7210 all phecode
613.5 Mastodynia Genitourinary 0.997 0.791 – 1.26 0.979 77 768 all phecode
613.7 Other signs and symptoms in breast Genitourinary 0.975 0.9 – 1.06 0.533 702 7013 all phecode
613.8 Other specified disorders of breast Genitourinary 1.09 0.972 – 1.23 0.136 327 3278 all phecode
613.9 Breast disorder NOS Genitourinary 0.91 0.782 – 1.06 0.226 207 2069 all phecode
614 Inflammatory diseases of female pelvic organs Genitourinary 1.05 1.02 – 1.08 0.00137 5711 57118 all phecode
614.1
Pelvic peritoneal adhesions, female
Pelvic peritoneal adhesions, female (postoperative) (postinfection)
 Genitourinary 1.04 1 – 1.09 0.0506 2538 25363 all phecode
614.3 Pelvic inflammatory disease (PID) Genitourinary 1.07 0.991 – 1.15 0.0859 830 8308 all phecode
614.31 Acute inflammatory pelvic disease Genitourinary 0.971 0.747 – 1.26 0.827 61 608 all phecode
614.32 Chronic inflammatory pelvic disease Genitourinary 1.13 1.02 – 1.24 0.0226 422 4221 all phecode
614.33 Pelvic inflammatory disease, NOS Genitourinary 1.05 0.935 – 1.17 0.436 351 3510 all phecode
614.4 Inflammatory diseases of uterus, except cervix Genitourinary 1.08 0.95 – 1.23 0.243 277 2775 all phecode
614.5
Inflammatory disease of cervix, vagina, and
Inflammatory disease of cervix, vagina, and vulva
 Genitourinary 1.05 1.01 – 1.1 0.0137 2601 26023 all phecode
614.51 Cervicitis and endocervicitis Genitourinary 0.995 0.939 – 1.05 0.862 1318 13189 all phecode
614.52 Vaginitis and vulvovaginitis Genitourinary 1.06 0.953 – 1.17 0.299 428 4273 all phecode
614.53 Cyst or abscess of Bartholin's gland Genitourinary 1.07 0.994 – 1.16 0.073 755 7574 all phecode
614.54 Abscess or ulceration of vulva Genitourinary 1.26 1.11 – 1.42 0.000306 274 2737 all phecode
615 Endometriosis Genitourinary 1.02 0.983 – 1.05 0.34 4029 40284 all phecode
617
Disorders secondary to childbirth, surgery
Disorders secondary to childbirth, surgery, trauma
 Genitourinary 1.1 0.977 – 1.24 0.114 304 3037 all phecode
618 Genital prolapse Genitourinary 1.02 1 – 1.04 0.0443 11689 116878 all phecode
618.1 Prolapse of vaginal walls Genitourinary 1.04 1.01 – 1.07 0.00234 7392 73940 all phecode
618.2 Uterine/Uterovaginal prolapse Genitourinary 0.995 0.966 – 1.02 0.725 5393 53918 all phecode
618.5 Prolapse of vaginal vault after hysterectomy Genitourinary 0.981 0.893 – 1.08 0.688 512 5125 all phecode
618.6 Vaginal enterocele, congenital or acquired Genitourinary 0.979 0.901 – 1.06 0.613 680 6794 all phecode
619 Noninflammatory female genital disorders Genitourinary 1.02 0.999 – 1.05 0.0582 8726 87297 all phecode
619.1
Noninflammatory disorders of ovary, fallopian
Noninflammatory disorders of ovary, fallopian tube, and broad ligament
 Genitourinary 1.01 0.939 – 1.1 0.709 729 7284 all phecode
619.2 Disorders of uterus, NEC Genitourinary 0.977 0.941 – 1.01 0.216 3324 33273 all phecode
619.3 Noninflammatory disorders of cervix Genitourinary 1 0.965 – 1.04 0.865 2860 28608 all phecode
619.4 Noninflammatory disorders of vagina Genitourinary 1.05 1 – 1.11 0.0424 1768 17669 all phecode
619.5 Noninflammatory disorders of vulva and perineum Genitourinary 1.08 1.02 – 1.14 0.0116 1350 13489 all phecode
620 Dysplasia of female genital organs Genitourinary 1.08 0.844 – 1.38 0.545 72 720 all phecode
621 Endometrial hyperplasia Genitourinary 1.01 0.944 – 1.07 0.868 1129 11294 all phecode
622 Polyp of female genital organs Genitourinary 0.972 0.952 – 0.992 0.00688 10480 104803 all phecode
622.1 Polyp of corpus uteri Genitourinary 0.974 0.951 – 0.998 0.0319 7857 78601 all phecode
622.2 Mucous polyp of cervix Genitourinary 0.965 0.93 – 1 0.0539 3442 34387 all phecode
623 Hypertrophy of female genital organs Genitourinary 0.985 0.929 – 1.05 0.629 1268 12684 all phecode
624 Symptoms involving female genital tract Genitourinary 0.921 0.855 – 0.993 0.0312 797 7961 all phecode
624.1 Dystrophy of female genital tract Genitourinary 0.952 0.831 – 1.09 0.479 237 2365 all phecode
624.2 Atrophy of female genital tract Genitourinary 0.877 0.794 – 0.969 0.00967 440 4398 all phecode
624.9 stress incontinence, female Genitourinary 1.1 1.07 – 1.13 9.28e-11 5865 58634 all phecode
625
Pain and other symptoms associated with female
Pain and other symptoms associated with female genital organs
 Genitourinary 1.06 1.02 – 1.1 0.00624 2876 28740 all phecode
625.1 Dyspareunia Genitourinary 1.06 0.993 – 1.12 0.0804 1188 11891 all phecode
626
Disorders of menstruation and other abnormal
Disorders of menstruation and other abnormal bleeding from female genital tract
 Genitourinary 1.05 1.03 – 1.07 4.55e-08 16168 115018 all phecode
626.1 Irregular menstrual cycle/bleeding Genitourinary 1.05 1.03 – 1.07 6.24e-08 14110 109918 all phecode
626.11 Absent or infrequent menstruation Genitourinary 1.08 0.895 – 1.31 0.415 109 1099 all phecode
626.12 Excessive or frequent menstruation Genitourinary 1.06 1.04 – 1.09 1.12e-08 9727 91749 all phecode
626.13 Irregular menstrual cycle Genitourinary 1.04 0.989 – 1.09 0.136 1985 19829 all phecode
626.14 Irregular menstrual bleeding Genitourinary 1.04 1 – 1.07 0.0348 3804 38021 all phecode
626.2 Dysmenorrhea Genitourinary 1.11 1.06 – 1.16 3.94e-05 1778 17767 all phecode
626.4 Premenstrual tension syndromes Genitourinary 1.36 1.15 – 1.6 0.000249 159 1587 all phecode
626.8 Infertility, female Genitourinary 0.999 0.945 – 1.06 0.981 1362 13613 all phecode
627 Menopausal and postmenopausal disorders Genitourinary 1 0.982 – 1.02 0.777 10392 103948 all phecode
627.1 Postmenopausal bleeding Genitourinary 1 0.98 – 1.03 0.846 9042 90439 all phecode
627.2 Symptomatic menopause Genitourinary 1.15 0.984 – 1.35 0.0793 183 1826 all phecode
627.3 Postmenopausal atrophic vaginitis Genitourinary 0.956 0.897 – 1.02 0.17 1111 11115 all phecode
627.4 Premenopausal menorrhagia Genitourinary 0.951 0.844 – 1.07 0.416 310 3097 all phecode
628 Ovarian cyst Genitourinary 1.06 1.03 – 1.1 5.37e-05 4747 47482 all phecode
634 Miscarriage; stillbirth Pregnancy Complications 1.04 1.01 – 1.07 0.0088 5218 36422 all phecode
634.1 Missed abortion/Hydatidiform mole Pregnancy Complications 1.03 0.969 – 1.09 0.346 1136 11300 all phecode
634.3 Ectopic pregnancy Pregnancy Complications 1.1 0.98 – 1.22 0.108 331 3305 all phecode
635
Hemorrhage during pregnancy; childbirth and
Hemorrhage during pregnancy; childbirth and postpartum
 Pregnancy Complications 0.957 0.914 – 1 0.0637 1974 17372 all phecode
635.2
Antepartum hemorrhage, abruptio placentae, and
Antepartum hemorrhage, abruptio placentae, and placenta previa
 Pregnancy Complications 0.961 0.897 – 1.03 0.256 866 8614 all phecode
635.3 Placenta previa and abruptio placenta Pregnancy Complications 0.933 0.881 – 0.987 0.0168 1270 12306 all phecode
636
Early or threatened labor; hemorrhage in early
Early or threatened labor; hemorrhage in early pregnancy
 Pregnancy Complications 1.03 0.985 – 1.07 0.208 2347 19972 all phecode
636.2 Early onset of delivery Pregnancy Complications 0.981 0.904 – 1.06 0.641 617 6144 all phecode
636.3 Hemorrhage in early pregnancy Pregnancy Complications 1.03 0.968 – 1.1 0.347 1082 10766 all phecode
638 Other high-risk pregnancy Pregnancy Complications 0.936 0.738 – 1.19 0.586 70 700 all phecode
642
Hypertension complicating pregnancy
Hypertension complicating pregnancy, childbirth, and the puerperium
 Pregnancy Complications 0.916 0.862 – 0.974 0.00495 1110 11074 all phecode
642.1 Preeclampsia and eclampsia Pregnancy Complications 0.904 0.805 – 1.02 0.0885 307 3058 all phecode
643 Excessive vomiting in pregnancy Pregnancy Complications 0.798 0.694 – 0.917 0.0015 215 2149 all phecode
643.1 Hyperemesis gravidarum Pregnancy Complications 0.753 0.637 – 0.89 0.00089 153 1525 all phecode
645 Late pregnancy and failed induction Pregnancy Complications 1.02 0.962 – 1.08 0.54 1250 12450 all phecode
646 Other complications of pregnancy NEC Pregnancy Complications 1.02 0.975 – 1.06 0.423 2228 20847 all phecode
647
Infectious and parasitic complications
Infectious and parasitic complications affecting pregnancy
 Pregnancy Complications 0.828 0.641 – 1.07 0.146 68 679 all phecode
647.1
Infections of genitourinary tract during
Infections of genitourinary tract during pregnancy
 Pregnancy Complications 0.992 0.882 – 1.12 0.897 275 2748 all phecode
649
Other conditions or status of the mother
Other conditions or status of the mother complicating pregnancy, childbirth, or the puerperium
 Pregnancy Complications 1.09 0.902 – 1.32 0.37 113 1129 all phecode
649.1
Diabetes or abnormal glucose tolerance
Diabetes or abnormal glucose tolerance complicating pregnancy
 Pregnancy Complications 0.953 0.824 – 1.1 0.512 193 1922 all phecode
650 Normal delivery Pregnancy Complications 0.959 0.916 – 1 0.0738 1922 18973 all phecode
651 Multiple gestation Pregnancy Complications 1.06 0.955 – 1.18 0.264 346 3454 all phecode
652
Malposition and malpresentation of fetus or
Malposition and malpresentation of fetus or obstruction
 Pregnancy Complications 0.985 0.938 – 1.03 0.537 1716 16521 all phecode
653
Problems associated with amniotic cavity and
Problems associated with amniotic cavity and membranes
 Pregnancy Complications 0.958 0.908 – 1.01 0.122 1401 13649 all phecode
654
Other and unspecified complications of birth
Other and unspecified complications of birth; puerperium affecting management of mother
 Pregnancy Complications 0.953 0.751 – 1.21 0.692 74 739 all phecode
655
Known or suspected fetal abnormality affecting
Known or suspected fetal abnormality affecting management of mother
 Pregnancy Complications 0.979 0.949 – 1.01 0.198 4306 29454 all phecode
656 Other perinatal conditions of fetus or newborn Pregnancy Complications 1.02 0.842 – 1.23 0.848 109 1080 all phecode
661 Fetal distress and abnormal forces of labor Pregnancy Complications 0.962 0.921 – 1 0.0756 2265 18397 all phecode
663
Umbilical cord complications during labor and
Umbilical cord complications during labor and delivery
 Pregnancy Complications 0.991 0.909 – 1.08 0.839 532 5316 all phecode
665 Obstetrical/birth trauma Pregnancy Complications 0.944 0.917 – 0.972 0.000112 5313 29472 all phecode
669 Complications of labor and delivery NEC Pregnancy Complications 0.957 0.919 – 0.996 0.0327 2552 21174 all phecode
671
Venous/cerebrovascular complications embolism
Venous/cerebrovascular complications embolism in pregnancy and the puerperium
 Pregnancy Complications 1.04 0.892 – 1.22 0.596 164 1628 all phecode
674 Other complications of the puerperium NEC Pregnancy Complications 0.957 0.843 – 1.09 0.493 262 2605 all phecode
676
Other disorders of the breast associated with
Other disorders of the breast associated with childbirth and disorders of lactation
 Pregnancy Complications 1 0.787 – 1.27 0.997 63 624 all phecode
679 Complications of in utero procedures Dermatologic 1.03 0.785 – 1.36 0.82 53 530 all phecode
681 Superficial cellulitis and abscess Dermatologic 1.1 1.07 – 1.13 6.73e-14 7200 72225 all phecode
681.1 Cellulitis and abscess of fingers/toes Dermatologic 0.956 0.876 – 1.04 0.306 563 5647 all phecode
681.2 Cellulitis and abscess of face/neck Dermatologic 1.16 1.06 – 1.28 0.00106 520 5208 all phecode
681.3 Cellulitis and abscess of arm/hand Dermatologic 1.1 1.07 – 1.14 3.8e-12 5481 55014 all phecode
681.5 Cellulitis and abscess of leg, except foot Dermatologic 1.1 1.07 – 1.14 5.24e-12 5487 55074 all phecode
681.6 Cellulitis and abscess of foot, toe Dermatologic 1.1 1.07 – 1.14 5.23e-12 5444 54643 all phecode
681.7 Cellulitis and abscess of trunk Dermatologic 1.19 1.09 – 1.3 5.96e-05 597 5987 all phecode
686
Other local infections of skin and subcutaneous
Other local infections of skin and subcutaneous tissue
 Dermatologic 1.15 1.08 – 1.22 2.29e-06 1337 13427 all phecode
686.1 Carbuncle and furuncle Dermatologic 1.18 1.13 – 1.23 1.38e-13 2284 22925 all phecode
686.3 Pilonidal cyst Dermatologic 1.31 1.2 – 1.43 1.17e-09 583 5837 all phecode
686.4 Pyogenic granuloma Dermatologic 0.943 0.846 – 1.05 0.29 362 3615 all phecode
687 Symptoms affecting skin Dermatologic 1.03 0.94 – 1.12 0.562 548 5508 all phecode
687.1 Rash and other nonspecific skin eruption Dermatologic 1.08 1.03 – 1.13 0.000706 2146 21470 all phecode
687.2 Localized superficial swelling, mass, or lump Dermatologic 1 0.888 – 1.13 0.977 283 2839 all phecode
687.3 Changes in skin texture Dermatologic 0.952 0.778 – 1.17 0.633 106 1070 all phecode
687.4 Disturbance of skin sensation Dermatologic 1.08 1.04 – 1.13 5.76e-05 2884 28859 all phecode
689 Disorder of skin and subcutaneous tissue NOS Dermatologic 1.03 1 – 1.06 0.0251 5747 57521 all phecode
690 Erythematosquamous dermatosis Dermatologic 1.13 0.882 – 1.45 0.337 71 710 all phecode
690.1 Seborrheic dermatitis Dermatologic 1.06 0.791 – 1.43 0.688 53 530 all phecode
691 Congenital anomalies of skin Dermatologic 1.04 0.855 – 1.26 0.707 120 1199 all phecode
694 Dyschromia and Vitiligo Dermatologic 0.984 0.921 – 1.05 0.624 986 9854 all phecode
694.1 Vitiligo Dermatologic 0.924 0.706 – 1.21 0.561 60 599 all phecode
694.2 Other dyschromia Dermatologic 0.993 0.923 – 1.07 0.86 782 7821 all phecode
694.3 Vascular disorders of skin Dermatologic 0.959 0.794 – 1.16 0.668 117 1170 all phecode
695 Erythematous conditions Dermatologic 1.09 1.05 – 1.14 3.47e-05 2379 23813 all phecode
695.1 Toxic erythema Dermatologic 1.15 0.948 – 1.39 0.156 109 1090 all phecode
695.2 Bullous dermatoses Dermatologic 1.02 0.852 – 1.22 0.827 137 1365 all phecode
695.21 Dermatitis herpetiformis Dermatologic 0.907 0.693 – 1.19 0.474 57 569 all phecode
695.22 Pemphigus and pemphigoid Dermatologic 0.968 0.755 – 1.24 0.797 73 727 all phecode
695.3 Rosacea Dermatologic 1.04 0.928 – 1.17 0.49 309 3097 all phecode
695.4 Lupus (localized and systemic) Dermatologic 1.14 1.03 – 1.26 0.0113 411 4114 all phecode
695.41 Cutaneous lupus erythematosus Dermatologic 1.37 1.14 – 1.65 0.000925 130 1295 all phecode
695.42 Systemic lupus erythematosus Dermatologic 1.09 0.978 – 1.23 0.117 340 3407 all phecode
695.7 Prurigo and Lichen Dermatologic 1.09 1.01 – 1.17 0.0336 775 7760 all phecode
695.8 Other specified erythematous conditions Dermatologic 1.19 1.03 – 1.36 0.0153 236 2359 all phecode
695.81 Erythema nodosum Dermatologic 0.995 0.782 – 1.27 0.967 76 760 all phecode
695.9 Unspecified erythematous condition Dermatologic 1.08 0.984 – 1.19 0.103 467 4672 all phecode
696 Psoriasis and related disorders Dermatologic 1.24 1.19 – 1.3 3.33e-22 2252 22509 all phecode
696.4 Psoriasis Dermatologic 1.24 1.19 – 1.29 2.84e-21 2198 21969 all phecode
696.41 Psoriasis vulgaris Dermatologic 1.29 1.23 – 1.36 2.45e-23 1680 16796 all phecode
696.42 Psoriatic arthropathy Dermatologic 1.14 1.06 – 1.24 0.000888 706 7052 all phecode
697 Sarcoidosis Dermatologic 0.906 0.827 – 0.993 0.0352 539 5373 all phecode
698 Pruritus and related conditions Dermatologic 1.07 0.99 – 1.15 0.0876 782 7814 all phecode
700 Corns and callosities Dermatologic 1.37 1.21 – 1.55 6.52e-07 291 2904 all phecode
701
Other hypertrophic and atrophic conditions of
Other hypertrophic and atrophic conditions of skin
 Dermatologic 1.08 1.05 – 1.11 1.15e-06 4663 46650 all phecode
701.1 Keratoderma, acquired Dermatologic 1.23 0.984 – 1.52 0.0689 87 870 all phecode
701.2 Scar conditions and fibrosis of skin Dermatologic 1.09 1.04 – 1.13 0.000167 2348 23478 all phecode
701.3 Circumscribed scleroderma Dermatologic 1.06 0.809 – 1.4 0.663 61 610 all phecode
701.4 Keloid scar Dermatologic 1.11 0.962 – 1.28 0.153 216 2159 all phecode
701.5 Abnormal granulation tissue Dermatologic 1 0.906 – 1.1 0.994 455 4568 all phecode
701.6 Acquired acanthosis nigricans Dermatologic 1.06 0.86 – 1.31 0.586 102 1019 all phecode
702
Degenerative skin conditions and other
Degenerative skin conditions and other dermatoses
 Dermatologic 0.998 0.97 – 1.03 0.904 5459 54587 all phecode
702.1 Actinic keratosis Dermatologic 1 0.962 – 1.04 0.904 2585 25842 all phecode
702.2 Seborrheic keratosis Dermatologic 0.995 0.958 – 1.03 0.795 3078 30772 all phecode
703 Diseases of nail, NOS Dermatologic 1.09 0.981 – 1.22 0.104 354 3539 all phecode
703.1 Ingrowing nail Dermatologic 1.03 0.967 – 1.11 0.323 966 9660 all phecode
704 Diseases of hair and hair follicles Dermatologic 1.07 1.04 – 1.1 8.76e-06 5267 52727 all phecode
704.1 Alopecia Dermatologic 1.04 0.867 – 1.25 0.655 125 1269 all phecode
704.8
Other specified diseases of hair and hair
Other specified diseases of hair and hair follicles
 Dermatologic 1.06 0.833 – 1.35 0.642 76 759 all phecode
705 Disorders of sweat glands Dermatologic 1.65 1.44 – 1.9 7.37e-13 228 2287 all phecode
705.3 Hidradenitis Dermatologic 1.87 1.6 – 2.2 6.73e-15 186 1868 all phecode
705.8 Hyperhidrosis Dermatologic 1.11 1.02 – 1.21 0.0145 591 5919 all phecode
706 Diseases of sebaceous glands Dermatologic 1.09 1.07 – 1.12 2.57e-14 8317 83195 all phecode
706.1 Acne Dermatologic 1.23 0.966 – 1.58 0.0921 78 779 all phecode
706.2 Sebaceous cyst Dermatologic 1.09 1.07 – 1.12 2.46e-15 8787 87882 all phecode
707 Chronic ulcer of skin Dermatologic 1.16 1.11 – 1.21 6.16e-10 1953 19654 all phecode
707.1 Decubitus ulcer Dermatologic 1.23 1.15 – 1.31 6.21e-09 909 9097 all phecode
709 Diffuse diseases of connective tissue Dermatologic 1.1 1.06 – 1.14 1.01e-07 3432 34317 all phecode
709.2 Sicca syndrome Dermatologic 1.08 0.986 – 1.19 0.0947 508 5073 all phecode
709.3 Systemic sclerosis Dermatologic 0.988 0.845 – 1.15 0.875 176 1753 all phecode
709.6
Other specified diffuse diseases of connective
Other specified diffuse diseases of connective tissue
 Dermatologic 1.01 0.785 – 1.3 0.938 65 649 all phecode
709.7 Unspecified diffuse connective tissue disease Dermatologic 1.11 1.07 – 1.16 3.04e-07 2714 27144 all phecode
710
Osteomyelitis, periostitis, and other
Osteomyelitis, periostitis, and other infections involving bone
 Musculoskeletal 1.18 1.09 – 1.29 0.000101 602 6034 all phecode
710.1 Osteomyelitis Musculoskeletal 1.16 1.06 – 1.27 0.000997 556 5574 all phecode
710.12 Chronic osteomyelitis Musculoskeletal 1.09 0.94 – 1.27 0.254 194 1947 all phecode
710.19 Unspecified osteomyelitis Musculoskeletal 1.17 1.06 – 1.3 0.00258 398 3997 all phecode
711 Arthropathy associated with infections Musculoskeletal 1.09 0.986 – 1.21 0.0913 421 4225 all phecode
711.1 Pyogenic arthritis Musculoskeletal 1.17 1.05 – 1.32 0.00644 328 3296 all phecode
712 Infective connective tissue disorders Musculoskeletal 1.1 0.877 – 1.38 0.41 81 810 all phecode
713
Arthropathy associated with other disorders
Arthropathy associated with other disorders classified elsewhere
 Musculoskeletal 1.16 0.984 – 1.38 0.0759 148 1499 all phecode
713.5
Arthropathy associated with neurological
Arthropathy associated with neurological disorders
 Musculoskeletal 1.21 0.945 – 1.56 0.129 65 669 all phecode
714
Rheumatoid arthritis and other inflammatory
Rheumatoid arthritis and other inflammatory polyarthropathies
 Musculoskeletal 1.21 1.17 – 1.25 1.18e-34 4832 48320 all phecode
714.1 Rheumatoid arthritis Musculoskeletal 1.21 1.17 – 1.25 4.16e-32 4372 43714 all phecode
715 Other inflammatory spondylopathies Musculoskeletal 1.13 1.08 – 1.19 1.34e-06 1659 16588 all phecode
715.1 Sacroiliitis NEC Musculoskeletal 1.12 0.925 – 1.36 0.241 113 1129 all phecode
715.2 Ankylosing spondylitis Musculoskeletal 1.13 1.04 – 1.23 0.00359 618 6177 all phecode
716 Other arthropathies Musculoskeletal 1.13 1.11 – 1.14 3.65e-99 37478 265375 all phecode
716.1 Unspecified polyarthropathy or polyarthritis Musculoskeletal 1.15 1.11 – 1.19 4.55e-14 3505 35090 all phecode
716.2 Unspecified monoarthritis Musculoskeletal 1.11 1.09 – 1.13 8.94e-33 15522 155339 all phecode
716.9 Arthropathy NOS Musculoskeletal 1.13 1.12 – 1.14 2.3e-97 35944 262308 all phecode
717 Polymyalgia Rheumatica Musculoskeletal 1.14 1.07 – 1.21 3.1e-05 1145 11480 all phecode
720 Spinal stenosis Musculoskeletal 1.18 1.14 – 1.22 1.76e-20 3705 37091 all phecode
721 Spondylosis and allied disorders Musculoskeletal 1.17 1.14 – 1.2 2.83e-39 7832 78318 all phecode
721.1 Spondylosis without myelopathy Musculoskeletal 1.17 1.13 – 1.2 4.68e-25 5045 50451 all phecode
721.2 Spondylosis with myelopathy Musculoskeletal 1.23 1.06 – 1.43 0.00609 189 1899 all phecode
721.8 Other allied disorders of spine Musculoskeletal 1.15 1.03 – 1.29 0.0122 352 3519 all phecode
722 Intervertebral disc disorders Musculoskeletal 1.18 1.16 – 1.21 1.61e-50 8978 89848 all phecode
722.1 Displacement of intervertebral disc Musculoskeletal 1.28 1.17 – 1.41 9.97e-08 512 5116 all phecode
722.6 Degeneration of intervertebral disc Musculoskeletal 1.22 1.18 – 1.27 2.39e-23 2831 28328 all phecode
722.8 Postlaminectomy syndrome Musculoskeletal 1.23 0.962 – 1.58 0.0983 67 669 all phecode
722.9 Other and unspecified disc disorder Musculoskeletal 1.17 1.13 – 1.2 5.14e-22 4407 44127 all phecode
723 Other disorders of cervical region Musculoskeletal 1.26 1.15 – 1.38 1.24e-06 517 5173 all phecode
723.1 Torticollis Musculoskeletal 1.26 1.03 – 1.53 0.0244 107 1068 all phecode
724 Other and unspecified disorders of back Musculoskeletal 1.15 1.09 – 1.2 7.54e-09 2052 20514 all phecode
724.1 Disorders of sacrum Musculoskeletal 1.18 1.07 – 1.32 0.00157 403 4024 all phecode
724.2 Disorders of coccyx Musculoskeletal 1.18 1.07 – 1.31 0.0016 406 4054 all phecode
724.8 Other symptoms referable to back Musculoskeletal 1.28 0.995 – 1.66 0.0549 63 630 all phecode
724.9 Other unspecified back disorders Musculoskeletal 1.13 1.08 – 1.19 2.16e-06 1614 16139 all phecode
726 Peripheral enthesopathies and allied syndromes Musculoskeletal 1.1 1.08 – 1.12 3.63e-28 14663 146691 all phecode
726.1 Enthesopathy Musculoskeletal 1.09 1.07 – 1.12 7.24e-16 9589 95900 all phecode
726.2 Synoviopathy Musculoskeletal 1.19 1.06 – 1.34 0.00272 334 3336 all phecode
726.3 Bursitis Musculoskeletal 1.1 1.02 – 1.18 0.0101 854 8573 all phecode
727 Other disorders of synovium, tendon, and bursa Musculoskeletal 1.11 1.08 – 1.13 3.31e-16 7331 73332 all phecode
727.1 Synovitis and tenosynovitis Musculoskeletal 1.11 1.07 – 1.16 3.57e-07 2737 27406 all phecode
727.2 Bursitis disorders Musculoskeletal 1.31 1.07 – 1.61 0.00925 103 1029 all phecode
727.4 Ganglion and cyst of synovium, tendon, and bursa Musculoskeletal 1.11 1.07 – 1.15 5.73e-08 3109 31085 all phecode
727.5 Rupture of synovium Musculoskeletal 1.1 1.01 – 1.2 0.0232 586 5854 all phecode
727.6 Rupture of tendon, nontraumatic Musculoskeletal 1.05 0.94 – 1.18 0.383 353 3527 all phecode
727.7 Contracture of tendon (sheath) Musculoskeletal 1.13 0.946 – 1.35 0.179 143 1429 all phecode
728 Disorders of muscle, ligament, and fascia Musculoskeletal 1.07 1.03 – 1.1 0.000163 3677 36788 all phecode
728.2 Laxity of ligament or hypermobility syndrome Musculoskeletal 1.04 0.94 – 1.15 0.437 412 4115 all phecode
728.7 Fasciitis Musculoskeletal 1.07 1.03 – 1.11 7.78e-05 3803 38045 all phecode
728.71
Contracture of palmar fascia [Dupuytren's
Contracture of palmar fascia [Dupuytren's disease]
 Musculoskeletal 1.07 1.03 – 1.11 0.000168 3477 34788 all phecode
729 Other disorders of soft tissues Musculoskeletal 1.13 1.1 – 1.16 4.84e-19 6014 60309 all phecode
729.1 Rheumatism, unspecified and fibrositis Musculoskeletal 1.14 1.07 – 1.22 7.55e-05 1005 10063 all phecode
729.3 Panniculitis Musculoskeletal 1.07 0.873 – 1.32 0.501 101 1009 all phecode
731
Osteitis deformans and osteopathies associated
Osteitis deformans and osteopathies associated with other disorders classified elsewhere
 Musculoskeletal 1.07 0.942 – 1.22 0.296 276 2758 all phecode
731.1 Osteitis deformans [Paget's disease of bone] Musculoskeletal 1.09 0.959 – 1.24 0.184 261 2609 all phecode
732 Osteochondropathies Musculoskeletal 1.04 0.941 – 1.14 0.458 467 4679 all phecode
732.1 Juvenile osteochondrosis Musculoskeletal 1.08 0.93 – 1.24 0.323 207 2068 all phecode
732.7 Osteochondritis dissecans Musculoskeletal 0.904 0.689 – 1.19 0.467 57 570 all phecode
733 Other disorders of bone and cartilage Musculoskeletal 1.09 1.04 – 1.15 0.000396 1777 17814 all phecode
733.2 Cyst of bone Musculoskeletal 1.05 0.932 – 1.18 0.423 311 3115 all phecode
733.4 Aseptic necrosis of bone Musculoskeletal 1.2 1.09 – 1.31 0.000107 540 5393 all phecode
733.6 Costochondritis Musculoskeletal 1.09 0.907 – 1.32 0.353 128 1276 all phecode
733.8 Malunion and nonunion of fracture Musculoskeletal 1.09 1.03 – 1.16 0.00414 1231 12313 all phecode
733.9 Chondromalacia Musculoskeletal 1.33 1.1 – 1.61 0.00381 121 1206 all phecode
735 Acquired foot deformities Musculoskeletal 1.06 1.03 – 1.08 7.61e-07 9603 96090 all phecode
735.1 Flat foot Musculoskeletal 1.12 0.958 – 1.3 0.16 189 1910 all phecode
735.2 Acquired toe deformities Musculoskeletal 1.06 1.03 – 1.09 0.000204 5070 50712 all phecode
735.21 Hammer toe (acquired) Musculoskeletal 1.08 1.03 – 1.14 0.00143 1929 19324 all phecode
735.23 Hallux rigidus Musculoskeletal 1.03 0.973 – 1.08 0.332 1555 15527 all phecode
735.3 Hallux valgus (Bunion) Musculoskeletal 1.05 1.02 – 1.08 0.000147 6643 66463 all phecode
736 Other acquired deformities of limbs Musculoskeletal 1.08 1.03 – 1.14 0.00224 1627 16282 all phecode
736.2 Acquired deformities of finger Musculoskeletal 0.995 0.874 – 1.13 0.943 248 2476 all phecode
737 Curvature of spine Musculoskeletal 1.08 1.01 – 1.15 0.0175 1128 11300 all phecode
737.3 Kyphoscoliosis and scoliosis Musculoskeletal 1.07 1 – 1.14 0.0347 1061 10632 all phecode
738 Other acquired musculoskeletal deformity Musculoskeletal 1.16 1.11 – 1.22 1.66e-09 1904 19058 all phecode
738.4 Acquired spondylolisthesis Musculoskeletal 1.18 1.11 – 1.24 4.13e-09 1513 15147 all phecode
739 Contracture of joint Musculoskeletal 1.04 0.948 – 1.15 0.392 488 4884 all phecode
740 Osteoarthrosis Musculoskeletal 1.11 1.09 – 1.12 2.43e-56 27707 231603 all phecode
740.1 Osteoarthritis; localized Musculoskeletal 1.09 1.08 – 1.11 2.19e-28 17412 169419 all phecode
740.11 Osteoarthrosis, localized, primary Musculoskeletal 1.09 1.07 – 1.12 2.56e-15 8974 89750 all phecode
740.12 Osteoarthrosis, localized, secondary Musculoskeletal 1.14 1.01 – 1.27 0.0269 348 3474 all phecode
740.2 Osteoarthrosis, generalized Musculoskeletal 1.1 1.01 – 1.2 0.0281 598 5969 all phecode
740.9 Osteoarthrosis NOS Musculoskeletal 1.14 1.12 – 1.17 8.35e-44 12270 122792 all phecode
741 Symptoms and disorders of the joints Musculoskeletal 1.06 1.03 – 1.1 0.00042 3563 35648 all phecode
741.1 Ankylosis of joint Musculoskeletal 0.884 0.719 – 1.09 0.242 102 1019 all phecode
741.2 Stiffness of joint Musculoskeletal 1.07 0.984 – 1.16 0.113 614 6146 all phecode
741.3 Difficulty in walking Musculoskeletal 1.1 0.93 – 1.3 0.264 154 1540 all phecode
741.4 Joint effusions Musculoskeletal 1.05 0.995 – 1.11 0.0762 1418 14197 all phecode
741.5 Hemarthrosis Musculoskeletal 1.07 0.877 – 1.3 0.52 110 1100 all phecode
741.6 Villonodular synovitis Musculoskeletal 1.02 0.785 – 1.33 0.872 54 535 all phecode
742 Derangement of joint, non-traumatic Musculoskeletal 1.08 1.04 – 1.12 0.000204 2843 28441 all phecode
742.1 Loose body in joint Musculoskeletal 1.09 0.976 – 1.22 0.122 333 3337 all phecode
742.2
Pathological, developmental or recurrent
Pathological, developmental or recurrent dislocation
 Musculoskeletal 0.99 0.804 – 1.22 0.924 95 960 all phecode
742.8 Articular cartilage disorder Musculoskeletal 1.09 0.998 – 1.2 0.0557 500 4996 all phecode
742.9 Other derangement of joint Musculoskeletal 1.07 1.02 – 1.12 0.00782 1993 19926 all phecode
743
Osteoporosis, osteopenia and pathological
Osteoporosis, osteopenia and pathological fracture
 Musculoskeletal 1.06 1.03 – 1.08 7.36e-06 7563 75729 all phecode
743.1 Osteoporosis Musculoskeletal 1.05 1.02 – 1.08 0.00039 6400 64107 all phecode
743.11 Osteoporosis NOS Musculoskeletal 1.04 1.01 – 1.07 0.00507 5549 55604 all phecode
743.13 Other specified osteoporosis Musculoskeletal 1.15 1.05 – 1.26 0.00176 529 5283 all phecode
743.2 Pathologic fracture Musculoskeletal 1.24 1.13 – 1.36 5.57e-06 516 5179 all phecode
743.9
Osteopenia or other disorder of bone and
Osteopenia or other disorder of bone and cartilage
 Musculoskeletal 1.06 0.988 – 1.14 0.103 815 8144 all phecode
745 Pain in joint Musculoskeletal 1.13 1.1 – 1.16 8.17e-25 7975 79789 all phecode
747 Cardiac and circulatory congenital anomalies Congenital Anomalies 1.14 1.09 – 1.18 2.3e-10 2802 28058 all phecode
747.1 Cardiac congenital anomalies Congenital Anomalies 1.13 1.09 – 1.18 1.18e-09 2628 26323 all phecode
747.11 Cardiac shunt/ heart septal defect Congenital Anomalies 1.08 0.994 – 1.18 0.0682 584 5838 all phecode
747.12 Valvular heart disease/ heart chambers Congenital Anomalies 0.997 0.872 – 1.14 0.96 235 2358 all phecode
747.13 Congenital anomalies of great vessels Congenital Anomalies 1.17 1.11 – 1.22 5.55e-10 1816 18200 all phecode
747.2
Congenital anomalies of peripheral vascular
Congenital anomalies of peripheral vascular system
 Congenital Anomalies 1.11 0.946 – 1.31 0.198 167 1680 all phecode
748 Anomalies of respiratory system, congenital Congenital Anomalies 1.32 0.993 – 1.75 0.0557 51 510 all phecode
749 Congenital anomalies of face and neck Congenital Anomalies 1.06 0.944 – 1.2 0.317 303 3029 all phecode
750 Digestive congenital anomalies Congenital Anomalies 1.03 0.952 – 1.12 0.455 686 6870 all phecode
750.1 Upper gastrointestinal congenital anomalies Congenital Anomalies 1.07 0.958 – 1.2 0.225 327 3263 all phecode
750.13 Congenital anomalies of mouth/tongue Congenital Anomalies 1.02 0.881 – 1.18 0.791 191 1909 all phecode
750.2 Lower gastrointestinal congenital anomalies Congenital Anomalies 0.973 0.871 – 1.09 0.625 356 3574 all phecode
750.21 Congenital anomalies of intestine Congenital Anomalies 0.99 0.861 – 1.14 0.888 225 2256 all phecode
750.22
Congenital anomaly of gallbladder, bile ducts
Congenital anomaly of gallbladder, bile ducts, liver, pancreas
 Congenital Anomalies 0.888 0.731 – 1.08 0.229 117 1179 all phecode
751 Genitourinary congenital anomalies Congenital Anomalies 1.04 0.988 – 1.1 0.133 1527 15286 all phecode
751.1 Congenital anomalies of genital organs Congenital Anomalies 1.02 0.939 – 1.1 0.697 694 6932 all phecode
751.11 Congenital anomalies of female genital organs Congenital Anomalies 1.01 0.92 – 1.12 0.779 455 4546 all phecode
751.12 Congenital anomalies of male genital organs Congenital Anomalies 1.01 0.88 – 1.16 0.908 222 2217 all phecode
751.2 Congenital anomalies of urinary system Congenital Anomalies 1.05 0.978 – 1.13 0.173 836 8385 all phecode
751.21 Cystic kidney disease Congenital Anomalies 1.06 0.958 – 1.17 0.257 424 4246 all phecode
751.22 Other specified congenital anomalies of kidney Congenital Anomalies 1.09 0.976 – 1.23 0.124 333 3346 all phecode
752 Nervous system congenital anomalies Congenital Anomalies 1.1 0.984 – 1.24 0.0921 328 3307 all phecode
752.1 Neural tube defects Congenital Anomalies 1.12 0.983 – 1.28 0.0878 253 2557 all phecode
752.11 Spina bifida Congenital Anomalies 1.17 1.01 – 1.35 0.0384 208 2108 all phecode
752.2
Other specified congenital anomalies of nervous
Other specified congenital anomalies of nervous system
 Congenital Anomalies 1.03 0.819 – 1.29 0.804 78 780 all phecode
753 Congenital anomalies of the eye Congenital Anomalies 1.06 0.879 – 1.27 0.552 127 1270 all phecode
753.1 Congenital cataract and lens anomalies Congenital Anomalies 1.01 0.793 – 1.28 0.949 76 760 all phecode
754 Congenital musculoskeletal deformities of spine Congenital Anomalies 1.03 0.843 – 1.25 0.796 109 1099 all phecode
755 Congenital anomalies of limbs Congenital Anomalies 1.08 0.975 – 1.19 0.143 425 4276 all phecode
755.1 Congenital deformities of feet Congenital Anomalies 1.09 0.947 – 1.26 0.224 208 2086 all phecode
755.6
Other congenital anomalies of lower limb
Other congenital anomalies of lower limb, including pelvic girdle
 Congenital Anomalies 1 0.848 – 1.18 0.983 160 1620 all phecode
755.61 Congenital hip dysplasia and deformity Congenital Anomalies 1.04 0.843 – 1.28 0.73 106 1070 all phecode
756 Other congenital musculoskeletal anomalies Congenital Anomalies 1.12 1.03 – 1.23 0.00768 587 5872 all phecode
756.3
Congenital anomalies of muscle, tendon, fascia
Congenital anomalies of muscle, tendon, fascia, and connective tissue
 Congenital Anomalies 1.23 0.97 – 1.55 0.0881 81 810 all phecode
756.5 Congenital osteodystrophies Congenital Anomalies 1.17 1.05 – 1.29 0.00268 435 4356 all phecode
758 Chromosomal anomalies and genetic disorders Congenital Anomalies 1.01 0.848 – 1.19 0.939 148 1708 all phecode
758.1 Chromosomal anomalies Congenital Anomalies 1.3 0.99 – 1.7 0.0594 60 830 all phecode
759 Other and unspecified congenital anomalies Congenital Anomalies 1.07 0.928 – 1.22 0.367 216 2159 all phecode
759.1 Anomalies of endocrine glands, congenital Congenital Anomalies 1.2 0.98 – 1.48 0.0772 96 959 all phecode
760 Back pain Symptoms 1.17 1.15 – 1.19 3.53e-53 11126 111353 all phecode
761 Cervicalgia Symptoms 1.16 1.11 – 1.22 2.21e-09 1791 17901 all phecode
764 Sciatica Symptoms 1.19 1.14 – 1.24 2.25e-15 2372 23732 all phecode
766 Neuralgia, neuritis, and radiculitis NOS Symptoms 1.13 1.07 – 1.2 6.51e-05 1172 11738 all phecode
770 Myalgia and myositis unspecified Symptoms 1.04 0.96 – 1.13 0.33 631 6311 all phecode
771 Musculoskeletal symptoms referable to limbs Symptoms 1.13 1.06 – 1.22 0.00046 870 8687 all phecode
771.1 Swelling of limb Symptoms 1.12 1.09 – 1.15 7.23e-13 4617 46330 all phecode
772 Symptoms of the muscles Symptoms 1.07 0.988 – 1.16 0.0959 659 6581 all phecode
773 Pain in limb Symptoms 1.13 1.1 – 1.16 2.6e-18 6209 62203 all phecode
780 Hypothermia/Chills Symptoms 1.13 0.963 – 1.33 0.133 171 1719 all phecode
781
Symptoms involving nervous and musculoskeletal
Symptoms involving nervous and musculoskeletal systems
 Symptoms 1.13 1.07 – 1.18 1.11e-06 1870 18715 all phecode
782.3 Edema Symptoms 1.16 1.1 – 1.22 7.81e-09 1642 16450 all phecode
782.6 Pallor and flushing Symptoms 1.22 1.04 – 1.43 0.0151 175 1748 all phecode
783 Fever of unknown origin Symptoms 1.04 1 – 1.07 0.0335 3911 39105 all phecode
785 Abdominal pain Symptoms 1.09 1.08 – 1.1 3.75e-60 40080 301686 all phecode
788 Syncope and collapse Symptoms 1.03 1.01 – 1.05 0.00795 9069 90813 all phecode
789 Nausea and vomiting Symptoms 1.09 1.07 – 1.11 4.67e-19 11577 115807 all phecode
790 Nonspecific findings on examination of blood Symptoms 1.04 0.876 – 1.24 0.65 150 1500 all phecode
790.1 Elevated sedimentation rate Symptoms 1.14 0.912 – 1.42 0.254 84 840 all phecode
790.6 Other abnormal blood chemistry Symptoms 1.02 0.992 – 1.04 0.175 6357 63635 all phecode
791 Gangrene Symptoms 1.12 1.03 – 1.23 0.0107 549 5501 all phecode
792
Abnormal Papanicolaou smear of cervix and
Abnormal Papanicolaou smear of cervix and cervical HPV
 Symptoms 1.33 1.08 – 1.64 0.00811 98 966 all phecode
793
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of musculoskeletal system
 Symptoms 1.17 0.974 – 1.4 0.0932 134 1340 all phecode
793.2
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of other intrathoracic organs (echocardiogram, etc)
 Symptoms 1.06 0.974 – 1.16 0.171 565 5647 all phecode
794
Abnormal results of other function studies
Abnormal results of other function studies (bladder, pancreas, placenta, spleen, etc)
 Symptoms 0.958 0.799 – 1.15 0.637 120 1198 all phecode
797 Shock Symptoms 1.03 0.877 – 1.21 0.723 156 1559 all phecode
797.1 Cardiogenic shock Symptoms 1.03 0.847 – 1.26 0.758 102 1020 all phecode
798 Malaise and fatigue Symptoms 1.05 1.01 – 1.09 0.00851 3408 34103 all phecode
798.1 Chronic fatigue syndrome Symptoms 0.943 0.864 – 1.03 0.184 591 5913 all phecode
800 Fracture of lower limb Injuries & Poisonings 1.07 1.05 – 1.1 1.99e-08 7035 70329 all phecode
800.1 Fracture of neck of femur Injuries & Poisonings 1.08 1.03 – 1.13 0.0022 1815 18152 all phecode
800.2 Fracture of unspecified part of femur Injuries & Poisonings 1.12 0.956 – 1.32 0.159 170 1693 all phecode
800.3 Fracture of tibia and fibula Injuries & Poisonings 1.08 1.03 – 1.13 0.000881 2158 21577 all phecode
800.4 Fracture of patella Injuries & Poisonings 1.08 1 – 1.16 0.048 766 7661 all phecode
801 Fracture of ankle and foot Injuries & Poisonings 1.12 1.07 – 1.17 4.12e-07 2205 22041 all phecode
801.1 Fracture of foot Injuries & Poisonings 1.1 1.05 – 1.15 0.000189 1835 18346 all phecode
802 Fracture of pelvis Injuries & Poisonings 1.03 0.955 – 1.12 0.423 718 7185 all phecode
803 Fracture of upper limb Injuries & Poisonings 1.01 0.985 – 1.03 0.511 8288 82880 all phecode
803.1 Fracture of humerus Injuries & Poisonings 1.02 0.965 – 1.07 0.552 1691 16883 all phecode
803.2 Fracture of radius and ulna Injuries & Poisonings 0.982 0.953 – 1.01 0.216 5215 52171 all phecode
803.3 Fracture of clavicle or scapula Injuries & Poisonings 1.09 1.03 – 1.15 0.00215 1518 15186 all phecode
804 Fracture of hand or wrist Injuries & Poisonings 1.06 1.02 – 1.1 0.00143 3339 33384 all phecode
805
Fracture of vertebral column without mention of
Fracture of vertebral column without mention of spinal cord injury
 Injuries & Poisonings 1.07 1.02 – 1.14 0.0131 1358 13565 all phecode
807 Fracture of ribs Injuries & Poisonings 1.16 1.08 – 1.25 9.13e-05 776 7752 all phecode
809 Fracture of unspecified bones Injuries & Poisonings 1.04 0.978 – 1.1 0.226 1300 12998 all phecode
817 Concussion Injuries & Poisonings 1.05 0.914 – 1.2 0.518 243 2428 all phecode
818 Intracranial hemorrhage (injury) Injuries & Poisonings 1.04 0.95 – 1.14 0.392 522 5213 all phecode
819
Skull and face fracture and other intercranial
Skull and face fracture and other intercranial injury
 Injuries & Poisonings 1.08 1.04 – 1.13 3.17e-05 2957 29596 all phecode
823 Torus fracture Injuries & Poisonings 1.09 1.04 – 1.15 0.000955 1673 16710 all phecode
830 Dislocation Injuries & Poisonings 1.07 1.02 – 1.12 0.00525 2088 20872 all phecode
835 Internal derangement of knee Injuries & Poisonings 1.06 1.04 – 1.08 2.3e-11 15221 152247 all phecode
836 Traumatic arthropathy Injuries & Poisonings 1.2 1.09 – 1.31 0.000138 526 5267 all phecode
840 Sprains and strains Injuries & Poisonings 0.963 0.875 – 1.06 0.444 470 4697 all phecode
850 Hemorrhage or hematoma complicating a procedure Injuries & Poisonings 1.09 1.06 – 1.12 5.32e-09 5259 52626 all phecode
851
Complications of transplants and reattached
Complications of transplants and reattached limbs
 Injuries & Poisonings 1.07 0.908 – 1.26 0.425 157 1567 all phecode
853 Complication of colostomy or enterostomy Injuries & Poisonings 1.19 1.08 – 1.3 0.000299 501 5010 all phecode
854
Complications of cardiac/vascular device
Complications of cardiac/vascular device, implant, and graft
 Injuries & Poisonings 1.26 1.2 – 1.33 4.1e-21 1826 18238 all phecode
857
Mechanical complication of unspecified
Mechanical complication of unspecified genitourinary device, implant, and graft
 Injuries & Poisonings 1.09 1.03 – 1.15 0.00424 1241 12418 all phecode
858 Complication of internal orthopedic device Injuries & Poisonings 1.14 1.09 – 1.18 1.77e-11 3158 31607 all phecode
859
Complication due to other implant and internal
Complication due to other implant and internal device
 Injuries & Poisonings 1.17 1.13 – 1.21 8.94e-17 3259 32599 all phecode
860 Bone marrow or stem cell transplant Neoplasms 0.792 0.616 – 1.02 0.07 68 680 all phecode
870 Open wounds of head; neck; and trunk Injuries & Poisonings 1.11 1.08 – 1.15 1.67e-09 3502 35062 all phecode
870.1 Open wound or laceration of eye or eyelid Injuries & Poisonings 1.14 1.01 – 1.3 0.0407 272 2713 all phecode
870.2 Open wound of ear Injuries & Poisonings 1.07 0.928 – 1.24 0.344 196 1949 all phecode
870.3 Other open wound of head and face Injuries & Poisonings 1.12 1.07 – 1.16 2.53e-08 2904 29085 all phecode
870.4 Open wound of nose and sinus Injuries & Poisonings 1.13 0.983 – 1.3 0.085 220 2199 all phecode
870.6 Open wound of neck Injuries & Poisonings 1.24 0.974 – 1.58 0.0811 68 678 all phecode
871 Open wounds of extremities Injuries & Poisonings 1.17 1.13 – 1.2 3.88e-20 4063 40648 all phecode
871.1 Open wound of hand except finger(s) Injuries & Poisonings 1.31 0.98 – 1.76 0.0684 53 530 all phecode
871.2 Open wound of finger(s) Injuries & Poisonings 0.966 0.782 – 1.19 0.745 91 900 all phecode
871.3 Open wound of foot except toe(s) alone Injuries & Poisonings 1.29 1.1 – 1.5 0.00143 178 1785 all phecode
872 Traumatic amputation Injuries & Poisonings 1.15 1.04 – 1.27 0.00468 475 4742 all phecode
873 Broken tooth Injuries & Poisonings 0.979 0.855 – 1.12 0.756 229 2289 all phecode
874 Complication of amputation stump Injuries & Poisonings 1.3 1.11 – 1.53 0.00101 169 1710 all phecode
905
Late effects of musculoskeletal and connective
Late effects of musculoskeletal and connective tissue injuries
 Injuries & Poisonings 1.16 0.985 – 1.36 0.076 157 1567 all phecode
907 Injuries to the nervous system Injuries & Poisonings 1.15 1.09 – 1.22 1.63e-06 1314 13140 all phecode
915 Superficial injury without mention of infection Injuries & Poisonings 1.07 1.04 – 1.11 1.03e-05 4260 42663 all phecode
916 Contusion Injuries & Poisonings 1.11 1.05 – 1.17 0.000123 1450 14506 all phecode
930 Allergic reaction to food Injuries & Poisonings 1.19 1.02 – 1.38 0.0282 179 1807 all phecode
938 Dermatitis due to solar radiation Injuries & Poisonings 0.94 0.848 – 1.04 0.236 389 3899 all phecode
938.2 Chronic dermatitis due to solar radiation Injuries & Poisonings 0.906 0.796 – 1.03 0.132 252 2530 all phecode
939
Atopic/contact dermatitis due to other or
Atopic/contact dermatitis due to other or unspecified
 Dermatologic 1.07 1.02 – 1.12 0.00596 2094 20961 all phecode
941 Adverse reaction to serum or vaccine Injuries & Poisonings 1.15 0.999 – 1.32 0.0515 225 2249 all phecode
942 Infusion and transfusion reaction Injuries & Poisonings 0.981 0.799 – 1.2 0.857 104 1038 all phecode
946 Anaphylactic shock NOS Injuries & Poisonings 1.23 1.13 – 1.35 3.27e-06 550 5509 all phecode
947 Urticaria Injuries & Poisonings 1.08 0.965 – 1.2 0.186 371 3707 all phecode
949 Allergies, other Injuries & Poisonings 1.01 0.911 – 1.12 0.822 397 3989 all phecode
952
Spinal cord injury without evidence of spinal
Spinal cord injury without evidence of spinal bone injury
 Injuries & Poisonings 1.13 1.02 – 1.25 0.0185 423 4224 all phecode
957 Injury to other and unspecified nerves Injuries & Poisonings 1.23 1.09 – 1.4 0.0011 269 2698 all phecode
958
Certain early complications of trauma or
Certain early complications of trauma or procedure
 Injuries & Poisonings 1.12 1.02 – 1.23 0.0227 491 4926 all phecode
958.1 Postoperative shock Injuries & Poisonings 1.07 0.801 – 1.43 0.645 55 555 all phecode
958.2 Traumatic and surgical subcutaneous emphysema Injuries & Poisonings 1.08 0.862 – 1.35 0.513 74 740 all phecode
960 Poisoning by antibiotics Injuries & Poisonings 1.07 1.06 – 1.09 2.6e-19 18100 181147 all phecode
960.2 Allergy/adverse effect of penicillin Injuries & Poisonings 1.08 1.06 – 1.1 4.18e-19 15846 158623 all phecode
961 Poisoning by other anti-infectives Injuries & Poisonings 1.1 0.993 – 1.22 0.0678 420 4195 all phecode
961.1 Poisoning/allergy of sulfonamides Injuries & Poisonings 1 0.933 – 1.08 0.935 869 8703 all phecode
962 Poisoning by hormones and synthetic substitutes Injuries & Poisonings 1.14 1.02 – 1.27 0.0176 371 3707 all phecode
962.3
Hormones and synthetic substitutes causing
Hormones and synthetic substitutes causing adverse effects in therapeutic use
 Injuries & Poisonings 1.17 1.05 – 1.31 0.00425 364 3638 all phecode
963 Poisoning by primarily systemic agents Injuries & Poisonings 1.36 1.19 – 1.57 1.23e-05 223 2228 all phecode
964
Poisoning by agents primarily affecting blood
Poisoning by agents primarily affecting blood constituents
 Injuries & Poisonings 1.19 1.06 – 1.35 0.00461 282 2830 all phecode
964.1 Anticoagulants causing adverse effects Injuries & Poisonings 1.22 1.08 – 1.38 0.0018 276 2770 all phecode
965
Poisoning by analgesics, antipyretics, and
Poisoning by analgesics, antipyretics, and antirheumatics
 Injuries & Poisonings 1.17 1.14 – 1.2 5.54e-30 6082 60875 all phecode
965.1
Opiates and related narcotics causing adverse
Opiates and related narcotics causing adverse effects in therapeutic use
 Injuries & Poisonings 1.09 1.02 – 1.16 0.00769 1144 11447 all phecode
965.2
Antirheumatics causing adverse effects in
Antirheumatics causing adverse effects in therapeutic use
 Injuries & Poisonings 1.39 1.27 – 1.53 1.04e-11 476 4767 all phecode
965.3
Salicylates causing adverse effects in
Salicylates causing adverse effects in therapeutic use
 Injuries & Poisonings 1.45 1.3 – 1.6 4.85e-12 403 4045 all phecode
966
Poisoning by anticonvulsants and
Poisoning by anticonvulsants and anti-Parkinsonism drugs
 Injuries & Poisonings 1.21 1.1 – 1.32 6.23e-05 512 5123 all phecode
967
Adverse effects of sedatives or other central
Adverse effects of sedatives or other central nervous system depressants and anesthetics
 Injuries & Poisonings 1.11 1.01 – 1.21 0.0236 583 5843 all phecode
969 Poisoning by psychotropic agents Injuries & Poisonings 1.34 1.28 – 1.41 2.25e-34 1950 19519 all phecode
971
Poisoning by drugs primarily affecting the
Poisoning by drugs primarily affecting the autonomic nervous system
 Injuries & Poisonings 1.48 1.27 – 1.71 3.41e-07 190 1908 all phecode
972
Poisoning by agents primarily affecting the
Poisoning by agents primarily affecting the cardiovascular system
 Injuries & Poisonings 1.45 1.27 – 1.65 3.15e-08 271 2717 all phecode
972.6 Antihypertensive agents causing adverse effects Injuries & Poisonings 1.37 1.09 – 1.72 0.00761 84 849 all phecode
973
Poisoning by agents primarily affecting the
Poisoning by agents primarily affecting the gastrointestinal system
 Injuries & Poisonings 1.44 1.18 – 1.76 0.000367 108 1080 all phecode
974
Poisoning by water, mineral, and uric acid
Poisoning by water, mineral, and uric acid metabolism drugs
 Injuries & Poisonings 1.36 1.1 – 1.67 0.00446 101 1018 all phecode
975
Poisoning by agents primarily acting on the
Poisoning by agents primarily acting on the smooth and skeletal muscles and respiratory system
 Injuries & Poisonings 1.38 1.06 – 1.78 0.0147 64 640 all phecode
976
Poisoning by agents primarily affecting skin &
Poisoning by agents primarily affecting skin & mucous membrane, ophthalmological, otorhinolaryngological, & dental drugs
 Injuries & Poisonings 1.29 0.987 – 1.69 0.0625 58 580 all phecode
977 Personal history of allergy to medicinal agents Injuries & Poisonings 1.17 1.02 – 1.35 0.0208 234 2337 all phecode
979 Adverse drug events and drug allergies Injuries & Poisonings 1.29 1.19 – 1.39 3.15e-10 698 6966 all phecode
981
Toxic effect of (non-ethyl) alcohol and
Toxic effect of (non-ethyl) alcohol and petroleum and other solvents
 Injuries & Poisonings 1.38 1.19 – 1.6 1.64e-05 200 1999 all phecode
986 Toxic effect of carbon monoxide Injuries & Poisonings 1.29 1.01 – 1.65 0.0383 62 620 all phecode
987 Toxic effect of other gases, fumes, or vapors Injuries & Poisonings 1.49 1.21 – 1.83 0.000146 105 1049 all phecode
988 Toxic effect of noxious substances eaten as food Injuries & Poisonings 1.08 0.897 – 1.3 0.41 111 1128 all phecode
989
Toxic effect of other substances, chiefly
Toxic effect of other substances, chiefly nonmedicinal as to source
 Injuries & Poisonings 1.21 0.974 – 1.5 0.0853 89 890 all phecode
990 Effects radiation NOS Injuries & Poisonings 1.1 1.06 – 1.14 9.13e-07 3113 31140 all phecode
994 Sepsis and SIRS Injuries & Poisonings 1.1 1.06 – 1.15 2.33e-07 3028 30268 all phecode
994.2 Sepsis Injuries & Poisonings 1.1 1.06 – 1.15 2.33e-07 3028 30268 all phecode
008 Intestinal infection Infectious Diseases 1.07 1.03 – 1.11 0.000433 3177 34779 exclusion phecode
008.5 Bacterial enteritis Infectious Diseases 1.09 1.02 – 1.17 0.0104 962 10653 exclusion phecode
008.52 Intestinal infection due to C. difficile Infectious Diseases 0.999 0.866 – 1.15 0.984 230 2513 exclusion phecode
008.6 Viral Enteritis Infectious Diseases 1.17 1.03 – 1.32 0.0152 316 3341 exclusion phecode
008.7 Intestinal infection due to protozoa Infectious Diseases 0.798 0.5 – 1.28 0.346 23 208 exclusion phecode
010 Tuberculosis Infectious Diseases 1.04 0.751 – 1.43 0.832 44 635 exclusion phecode
038 Septicemia Infectious Diseases 1.03 0.971 – 1.09 0.337 1419 15777 exclusion phecode
038.1 Gram negative septicemia Infectious Diseases 1.09 0.96 – 1.23 0.191 307 3119 exclusion phecode
038.2 Gram positive septicemia Infectious Diseases 0.984 0.832 – 1.16 0.855 158 1883 exclusion phecode
041 Bacterial infection NOS Infectious Diseases 1.06 1.02 – 1.1 0.00085 4072 46494 exclusion phecode
041.1 Staphylococcus infections Infectious Diseases 1.06 0.992 – 1.13 0.0826 1028 11962 exclusion phecode
041.2 Streptococcus infection Infectious Diseases 1.06 0.969 – 1.16 0.2 558 6335 exclusion phecode
041.4 E. coli Infectious Diseases 1.05 0.978 – 1.13 0.183 961 10739 exclusion phecode
053 Herpes zoster Infectious Diseases 1.13 0.945 – 1.35 0.181 139 1617 exclusion phecode
053.1 Herpes zoster with nervous system complications Infectious Diseases 1.3 0.889 – 1.89 0.178 29 359 exclusion phecode
054 Herpes simplex Infectious Diseases 1.11 0.852 – 1.44 0.446 78 801 exclusion phecode
070 Viral hepatitis Infectious Diseases 1.15 0.958 – 1.37 0.135 144 2278 exclusion phecode
070.1 Viral hepatitis A Infectious Diseases 1.48 0.918 – 2.38 0.107 22 282 exclusion phecode
070.2 Viral hepatitis B Infectious Diseases 1.5 1.07 – 2.11 0.0201 39 485 exclusion phecode
070.3 Viral hepatitis C Infectious Diseases 1.35 0.973 – 1.89 0.0726 36 1048 exclusion phecode
070.4 Chronic hepatitis Infectious Diseases 1.2 0.973 – 1.47 0.0883 113 1132 exclusion phecode
070.9 Hepatitis NOS Infectious Diseases 1.12 0.941 – 1.34 0.197 147 1607 exclusion phecode
071 Human immunodeficiency virus [HIV] disease Infectious Diseases 1.05 0.749 – 1.48 0.771 39 543 exclusion phecode
071.1 HIV infection, symptomatic Infectious Diseases 0.953 0.65 – 1.4 0.807 33 438 exclusion phecode
078 Viral warts & HPV Infectious Diseases 0.993 0.887 – 1.11 0.899 358 4009 exclusion phecode
079 Viral infection Infectious Diseases 1.08 1.01 – 1.15 0.0235 1100 11167 exclusion phecode
079.1 Varicella infection Infectious Diseases 0.86 0.571 – 1.29 0.469 24 281 exclusion phecode
080 Postoperative infection Infectious Diseases 1.05 0.995 – 1.11 0.0742 1460 17445 exclusion phecode
081
Infection/inflammation of internal prosthetic
Infection/inflammation of internal prosthetic device; implant; and graft
 Infectious Diseases 1.06 0.981 – 1.14 0.146 813 9364 exclusion phecode
090
Sexually transmitted infections (not HIV or
Sexually transmitted infections (not HIV or hepatitis)
 Infectious Diseases 1.02 0.666 – 1.55 0.941 29 264 exclusion phecode
1000 Burns Injuries & Poisonings 1 0.866 – 1.16 0.972 215 2207 exclusion phecode
1001 Foreign body injury Injuries & Poisonings 1.18 1.06 – 1.31 0.00191 418 4598 exclusion phecode
1002
Symptoms concerning nutrition, metabolism, and
Symptoms concerning nutrition, metabolism, and development
 Injuries & Poisonings 1.03 0.978 – 1.08 0.275 1908 21313 exclusion phecode
1004
Other signs and symptoms involving emotional
Other signs and symptoms involving emotional state
 Injuries & Poisonings 1.09 0.867 – 1.37 0.458 86 1181 exclusion phecode
1005 Other symptoms Injuries & Poisonings 0.986 0.892 – 1.09 0.789 467 5561 exclusion phecode
1006 Crushing injury Injuries & Poisonings 1.11 0.859 – 1.44 0.419 70 957 exclusion phecode
1007 Injury to blood vessels Injuries & Poisonings 1.15 0.905 – 1.47 0.249 80 964 exclusion phecode
1008 Crushing or internal injury to organs Injuries & Poisonings 1.05 0.935 – 1.19 0.388 315 3778 exclusion phecode
1009 Injury, NOS Injuries & Poisonings 1.04 0.999 – 1.08 0.0538 3040 32507 exclusion phecode
1010 Other tests Injuries & Poisonings 1.04 0.99 – 1.09 0.126 2152 23132 exclusion phecode
1011 Complications of surgical and medical procedures Injuries & Poisonings 1.08 1.04 – 1.13 4.44e-05 3153 35115 exclusion phecode
1012 Late effect Injuries & Poisonings 0.894 0.655 – 1.22 0.48 46 427 exclusion phecode
1013 Asphyxia and hypoxemia Injuries & Poisonings 1.04 0.842 – 1.29 0.714 94 1174 exclusion phecode
1014 Effects of heat, cold and air pressure Injuries & Poisonings 0.948 0.649 – 1.38 0.781 27 273 exclusion phecode
1015 Effects of other external causes Injuries & Poisonings 1.14 1.07 – 1.21 1.29e-05 1374 16745 exclusion phecode
1019
Other ill-defined and unknown causes of
Other ill-defined and unknown causes of morbidity and mortality
 Injuries & Poisonings 1.04 1.01 – 1.07 0.0145 5742 62339 exclusion phecode
110 Dermatophytosis / Dermatomycosis Infectious Diseases 1.05 0.84 – 1.31 0.665 91 1032 exclusion phecode
110.1 Dermatophytosis Infectious Diseases 1.02 0.812 – 1.27 0.893 90 999 exclusion phecode
110.11 Dermatophytosis of nail Infectious Diseases 1.18 0.788 – 1.76 0.427 27 281 exclusion phecode
110.12 Althete's foot Infectious Diseases 0.903 0.653 – 1.25 0.535 40 502 exclusion phecode
112 Candidiasis Infectious Diseases 1.08 0.989 – 1.17 0.0875 673 8316 exclusion phecode
117 Mycoses Infectious Diseases 1.09 0.877 – 1.36 0.435 92 1074 exclusion phecode
117.4 Aspergillosis Infectious Diseases 1.07 0.83 – 1.38 0.597 66 628 exclusion phecode
130 Spirochetal infection Infectious Diseases 1.2 0.795 – 1.8 0.389 29 262 exclusion phecode
133 Arthropod-borne diseases Infectious Diseases 0.951 0.637 – 1.42 0.807 31 254 exclusion phecode
134 Helminthiases Infectious Diseases 1.3 0.943 – 1.79 0.109 45 539 exclusion phecode
134.1 Intestinal helminthiases Infectious Diseases 1.21 0.844 – 1.74 0.298 38 436 exclusion phecode
136 Other infectious and parasitic diseases Infectious Diseases 1.05 0.843 – 1.32 0.648 90 790 exclusion phecode
145 Cancer of mouth Neoplasms 0.967 0.818 – 1.14 0.688 167 2371 exclusion phecode
145.2 Cancer of tongue Neoplasms 1.08 0.854 – 1.36 0.532 87 1121 exclusion phecode
145.3 Cancer of major salivary glands Neoplasms 0.669 0.477 – 0.938 0.0199 38 404 exclusion phecode
145.5 Cancer of the mouth floor Neoplasms 1.1 0.536 – 2.28 0.787 5 201 exclusion phecode
149 Cancer of larynx, pharynx, nasal cavities Neoplasms 0.956 0.793 – 1.15 0.642 121 2266 exclusion phecode
149.1 Cancer of oropharynx Neoplasms 0.852 0.629 – 1.15 0.302 47 962 exclusion phecode
149.4 Cancer of larynx Neoplasms 1.26 0.892 – 1.77 0.191 36 868 exclusion phecode
149.9 Cancer of of nasal cavities Neoplasms 0.867 0.557 – 1.35 0.526 22 196 exclusion phecode
150 Cancer of esophagus Neoplasms 1.15 0.981 – 1.34 0.085 175 2710 exclusion phecode
151 Cancer of stomach Neoplasms 1.06 0.898 – 1.25 0.489 158 2000 exclusion phecode
153 Colorectal cancer Neoplasms 0.976 0.924 – 1.03 0.377 1522 16806 exclusion phecode
153.2 Colon cancer Neoplasms 0.995 0.931 – 1.06 0.877 1047 11461 exclusion phecode
153.3
Malignant neoplasm of rectum, rectosigmoid
Malignant neoplasm of rectum, rectosigmoid junction, and anus
 Neoplasms 0.988 0.912 – 1.07 0.757 699 7933 exclusion phecode
155 Cancer of liver and intrahepatic bile duct Neoplasms 1.09 0.903 – 1.32 0.358 120 1459 exclusion phecode
155.1 Malignant neoplasm of liver, primary Neoplasms 0.862 0.636 – 1.17 0.336 48 585 exclusion phecode
157 Pancreatic cancer Neoplasms 1.19 1.03 – 1.37 0.0185 223 2531 exclusion phecode
158
Neoplasm of unspecified nature of digestive
Neoplasm of unspecified nature of digestive system
 Neoplasms 0.949 0.844 – 1.07 0.38 343 3933 exclusion phecode
159
Malignant neoplasm of other and ill-defined
Malignant neoplasm of other and ill-defined sites within the digestive organs and peritoneum
 Neoplasms 0.987 0.939 – 1.04 0.618 1833 20591 exclusion phecode
159.2
Malignant neoplasm of small intestine
Malignant neoplasm of small intestine, including duodenum
 Neoplasms 0.779 0.603 – 1.01 0.0556 71 687 exclusion phecode
159.3
Malignant neoplasm of gallbladder and
Malignant neoplasm of gallbladder and extrahepatic bile ducts
 Neoplasms 1.23 0.942 – 1.61 0.129 68 799 exclusion phecode
159.4
Malignant neoplasm of retroperitoneum and
Malignant neoplasm of retroperitoneum and peritoneum
 Neoplasms 0.908 0.715 – 1.15 0.426 84 766 exclusion phecode
164 Cancer of intrathoracic organs Neoplasms 0.732 0.467 – 1.15 0.175 22 225 exclusion phecode
165 Cancer within the respiratory system Neoplasms 1.04 0.937 – 1.15 0.462 394 10584 exclusion phecode
165.1 Cancer of bronchus; lung Neoplasms 0.99 0.867 – 1.13 0.886 245 8453 exclusion phecode
170 Cancer of bone and connective tissue Neoplasms 0.978 0.827 – 1.16 0.791 161 1671 exclusion phecode
170.1 Bone cancer Neoplasms 0.952 0.679 – 1.33 0.773 37 494 exclusion phecode
170.2 Cancer of connective tissue Neoplasms 1.04 0.862 – 1.25 0.704 133 1272 exclusion phecode
172 Skin cancer Neoplasms 0.983 0.955 – 1.01 0.271 5307 50279 exclusion phecode
172.1 Melanomas of skin, dx or hx Neoplasms 1.02 0.958 – 1.09 0.531 1159 10294 exclusion phecode
172.11 Melanomas of skin Neoplasms 1.02 0.962 – 1.09 0.451 1173 10450 exclusion phecode
172.2 Other non-epithelial cancer of skin Neoplasms 0.971 0.94 – 1 0.0839 4234 40589 exclusion phecode
172.3 Carcinoma in situ of skin Neoplasms 0.996 0.869 – 1.14 0.949 247 2505 exclusion phecode
173 Neoplasm of uncertain behavior of skin Neoplasms 0.926 0.721 – 1.19 0.55 73 773 exclusion phecode
174 Breast cancer Neoplasms 1.02 0.986 – 1.05 0.293 5300 54872 exclusion phecode
174.1 Breast cancer [female] Neoplasms 1.02 0.988 – 1.05 0.225 5232 54081 exclusion phecode
174.11 Malignant neoplasm of female breast Neoplasms 1.02 0.984 – 1.05 0.33 4903 50986 exclusion phecode
174.3 Neoplasm of uncertain behavior of breast Neoplasms 0.719 0.528 – 0.979 0.0364 51 490 exclusion phecode
175 Acquired absence of breast Neoplasms 0.979 0.911 – 1.05 0.556 944 10497 exclusion phecode
180 Cervical cancer and dysplasia Neoplasms 1.05 0.97 – 1.13 0.248 846 9684 exclusion phecode
180.1 Cervical cancer Neoplasms 1.15 0.933 – 1.41 0.192 108 1156 exclusion phecode
180.3
Cervical intraepithelial neoplasia [CIN]
Cervical intraepithelial neoplasia [CIN] [Cervical dysplasia]
 Neoplasms 1.03 0.952 – 1.11 0.474 795 9250 exclusion phecode
182 Malignant neoplasm of uterus Neoplasms 1.07 0.978 – 1.17 0.137 621 5471 exclusion phecode
184 Cancer of other female genital organs Neoplasms 1.01 0.921 – 1.11 0.825 589 6068 exclusion phecode
184.1
Malignant neoplasm of ovary and other uterine
Malignant neoplasm of ovary and other uterine adnexa
 Neoplasms 1.04 0.93 – 1.15 0.523 436 4284 exclusion phecode
184.11 Malignant neoplasm of ovary Neoplasms 1.04 0.937 – 1.16 0.428 426 4154 exclusion phecode
184.2
Cancer of other female genital organs
Cancer of other female genital organs (excluding uterus and ovary)
 Neoplasms 0.859 0.696 – 1.06 0.156 110 1305 exclusion phecode
185 Cancer of prostate Neoplasms 1.02 0.973 – 1.07 0.401 1930 17672 exclusion phecode
187 Cancer of other male genital organs Neoplasms 0.895 0.755 – 1.06 0.2 157 1642 exclusion phecode
187.1
Malignant neoplasm of unspecified male genital
Malignant neoplasm of unspecified male genital organ
 Neoplasms 0.727 0.468 – 1.13 0.158 25 230 exclusion phecode
187.2 Malignant neoplasm of testis Neoplasms 0.935 0.763 – 1.15 0.518 108 1089 exclusion phecode
187.8
Neoplasm of uncertain behavior of male genital
Neoplasm of uncertain behavior of male genital organs
 Neoplasms 0.864 0.62 – 1.21 0.39 39 378 exclusion phecode
189
Cancer of urinary organs (incl. kidney and
Cancer of urinary organs (incl. kidney and bladder)
 Neoplasms 0.983 0.923 – 1.05 0.607 1112 14382 exclusion phecode
189.1 Cancer of kidney and renal pelvis Neoplasms 1.06 0.945 – 1.2 0.306 322 3728 exclusion phecode
189.11 Malignant neoplasm of kidney, except pelvis Neoplasms 1.07 0.946 – 1.21 0.288 307 3572 exclusion phecode
189.12 Malignant neoplasm of renal pelvis Neoplasms 1.04 0.655 – 1.66 0.858 22 221 exclusion phecode
189.2 Cancer of bladder Neoplasms 0.936 0.858 – 1.02 0.139 572 8283 exclusion phecode
189.21 Malignant neoplasm of bladder Neoplasms 0.964 0.876 – 1.06 0.455 482 7337 exclusion phecode
189.4 Malignant neoplasm of other urinary organs Neoplasms 0.833 0.608 – 1.14 0.256 47 482 exclusion phecode
190 Cancer of eye Neoplasms 0.924 0.718 – 1.19 0.541 75 652 exclusion phecode
191
Manlignant and unknown neoplasms of brain and
Manlignant and unknown neoplasms of brain and nervous system
 Neoplasms 1.04 0.914 – 1.19 0.524 251 2591 exclusion phecode
191.1 Cancer of brain and nervous system Neoplasms 1.06 0.917 – 1.22 0.433 209 2114 exclusion phecode
191.11 Cancer of brain Neoplasms 1.1 0.939 – 1.28 0.247 186 1939 exclusion phecode
193 Thyroid cancer Neoplasms 1.1 0.914 – 1.32 0.316 136 1451 exclusion phecode
194 Cancer of other endocrine glands Neoplasms 0.855 0.58 – 1.26 0.427 31 359 exclusion phecode
195 Cancer, suspected or other Neoplasms 1.01 0.982 – 1.04 0.499 5912 62463 exclusion phecode
195.1 Malignant neoplasm, other Neoplasms 1.01 0.984 – 1.04 0.389 5647 59995 exclusion phecode
197 Chemotherapy Neoplasms 1.06 1.04 – 1.09 1.49e-06 7740 84536 exclusion phecode
198 Secondary malignant neoplasm Neoplasms 1.02 0.987 – 1.06 0.205 3219 37209 exclusion phecode
198.1 Secondary malignancy of lymph nodes Neoplasms 1.01 0.96 – 1.06 0.71 1900 21401 exclusion phecode
198.2 Secondary malignancy of respiratory organs Neoplasms 1.02 0.944 – 1.11 0.602 729 8750 exclusion phecode
198.3
Secondary malignant neoplasm of digestive
Secondary malignant neoplasm of digestive systems
 Neoplasms 1.02 0.931 – 1.11 0.692 601 6098 exclusion phecode
198.4 Secondary malignant neoplasm of liver Neoplasms 1.07 1 – 1.15 0.0473 904 10195 exclusion phecode
198.5 Secondary malignancy of brain/spine Neoplasms 0.989 0.857 – 1.14 0.884 222 3326 exclusion phecode
198.6 Secondary malignancy of bone Neoplasms 1.09 1 – 1.18 0.0481 667 8166 exclusion phecode
198.7 Secondary malignant neoplasm of skin Neoplasms 0.963 0.747 – 1.24 0.771 68 735 exclusion phecode
199 Neoplasm of uncertain behavior Neoplasms 1.07 0.97 – 1.17 0.18 523 5675 exclusion phecode
199.4 Neurofibromatosis Neoplasms 0.998 0.723 – 1.38 0.99 38 415 exclusion phecode
200 Myeloproliferative disease Neoplasms 0.994 0.881 – 1.12 0.918 325 3723 exclusion phecode
200.1 Polycythemia vera Neoplasms 1.18 0.968 – 1.43 0.102 118 1391 exclusion phecode
201 Hodgkin's disease Neoplasms 0.834 0.67 – 1.04 0.103 87 1050 exclusion phecode
202 Cancer of other lymphoid, histiocytic tissue Neoplasms 1.03 0.956 – 1.11 0.439 835 8401 exclusion phecode
202.2 Non-Hodgkins lymphoma Neoplasms 1 0.92 – 1.09 0.998 666 6726 exclusion phecode
202.21 Nodular lymphoma Neoplasms 1.14 0.953 – 1.36 0.156 152 1391 exclusion phecode
202.24 Large cell lymphoma Neoplasms 0.884 0.768 – 1.02 0.0875 236 2197 exclusion phecode
204 Leukemia Neoplasms 1.02 0.933 – 1.11 0.681 589 6010 exclusion phecode
204.1 Lymphoid leukemia Neoplasms 1.08 0.922 – 1.26 0.347 186 2061 exclusion phecode
204.11 Lymphoid leukemia, acute Neoplasms 1.37 0.909 – 2.07 0.133 23 186 exclusion phecode
204.12 Lymphoid leukemia, chronic Neoplasms 1.01 0.858 – 1.2 0.866 165 1806 exclusion phecode
204.2 Myeloid leukemia Neoplasms 0.96 0.815 – 1.13 0.622 166 1705 exclusion phecode
204.21 Myeloid leukemia, acute Neoplasms 0.925 0.756 – 1.13 0.453 113 1190 exclusion phecode
204.22 Myeloid leukemia, chronic Neoplasms 1.07 0.814 – 1.4 0.64 56 554 exclusion phecode
204.4 Multiple myeloma Neoplasms 0.989 0.851 – 1.15 0.884 198 1981 exclusion phecode
208 Benign neoplasm of colon Neoplasms 1.01 0.98 – 1.04 0.609 6119 72426 exclusion phecode
210 Benign neoplasm of lip, oral cavity, and pharynx Neoplasms 0.956 0.848 – 1.08 0.462 324 3798 exclusion phecode
211
Benign neoplasm of other parts of digestive
Benign neoplasm of other parts of digestive system
 Neoplasms 1.01 0.963 – 1.06 0.713 2251 20415 exclusion phecode
212
Benign neoplasm of respiratory and
Benign neoplasm of respiratory and intrathoracic organs
 Neoplasms 1.13 0.929 – 1.39 0.217 116 1317 exclusion phecode
213 Benign neoplasm of bone and articular cartilage Neoplasms 1.03 0.841 – 1.26 0.793 119 1267 exclusion phecode
214 Lipoma Neoplasms 1.1 1.05 – 1.15 5.89e-05 2214 23879 exclusion phecode
214.1 Lipoma of skin and subcutaneous tissue Neoplasms 1.1 1.04 – 1.16 0.000533 1650 17881 exclusion phecode
215
Other benign neoplasm of connective and other
Other benign neoplasm of connective and other soft tissue
 Neoplasms 1.14 1.02 – 1.26 0.0154 427 4424 exclusion phecode
216 Benign neoplasm of skin Neoplasms 1.06 1.02 – 1.1 0.00333 3109 30604 exclusion phecode
217 Vascular hamartomas and non-neoplastic nevi Neoplasms 1.01 0.875 – 1.17 0.886 216 2471 exclusion phecode
217.1 Nevus, non-neoplastic Neoplasms 1.01 0.868 – 1.17 0.912 207 2282 exclusion phecode
218 Benign neoplasm of uterus Neoplasms 1.02 0.99 – 1.06 0.163 4555 44195 exclusion phecode
218.1 Uterine leiomyoma Neoplasms 1.02 0.983 – 1.05 0.335 4633 45030 exclusion phecode
218.2 Other benign neoplasm of uterus Neoplasms 1.07 0.899 – 1.27 0.453 164 1490 exclusion phecode
220 Benign neoplasm of ovary Neoplasms 1.02 0.93 – 1.11 0.702 612 6346 exclusion phecode
221 Benign neoplasm of other female genital organs Neoplasms 0.96 0.772 – 1.19 0.714 96 997 exclusion phecode
222 Benign neoplasm of male genital organs Neoplasms 0.91 0.676 – 1.23 0.535 58 521 exclusion phecode
223
Benign neoplasm of kidney and other urinary
Benign neoplasm of kidney and other urinary organs
 Neoplasms 0.95 0.71 – 1.27 0.732 47 633 exclusion phecode
224 Benign neoplasm of eye Neoplasms 0.992 0.726 – 1.35 0.958 50 505 exclusion phecode
224.1 Benign neoplasm of eye, uveal Neoplasms 1.38 0.889 – 2.16 0.15 24 249 exclusion phecode
225
Benign neoplasm of brain and other parts of
Benign neoplasm of brain and other parts of nervous system
 Neoplasms 1.14 1.02 – 1.29 0.0272 343 3244 exclusion phecode
225.1
Benign neoplasm of brain, cranial nerves
Benign neoplasm of brain, cranial nerves, meninges
 Neoplasms 1.11 0.986 – 1.26 0.084 317 3067 exclusion phecode
225.2 Benign neoplasm of spinal cord, meninges Neoplasms 1.39 0.911 – 2.11 0.128 30 267 exclusion phecode
226 Benign neoplasm of thyroid glands Neoplasms 0.858 0.705 – 1.04 0.124 127 1107 exclusion phecode
227
Benign neoplasm of other endocrine glands and
Benign neoplasm of other endocrine glands and related structures
 Neoplasms 1.1 0.975 – 1.24 0.123 333 3441 exclusion phecode
227.1 Benign neoplasm of adrenal gland Neoplasms 1.08 0.79 – 1.47 0.638 46 733 exclusion phecode
227.2 Benign neoplasm of parathyroid gland Neoplasms 1.01 0.848 – 1.21 0.888 152 1532 exclusion phecode
227.3
Benign neoplasm of pituitary gland and
Benign neoplasm of pituitary gland and craniopharyngeal duct (pouch)
 Neoplasms 1.26 1.04 – 1.52 0.0196 135 1220 exclusion phecode
228 Hemangioma and lymphangioma, any site Neoplasms 0.963 0.881 – 1.05 0.408 609 6262 exclusion phecode
229 Benign neoplasm of unspecified sites Neoplasms 1.03 0.958 – 1.1 0.44 964 9633 exclusion phecode
240 Simple and unspecified goiter Endocrine/metabolic 1.02 0.89 – 1.17 0.76 257 2549 exclusion phecode
241 Nontoxic nodular goiter Endocrine/metabolic 0.95 0.859 – 1.05 0.323 468 4632 exclusion phecode
241.1 Nontoxic uninodular goiter Endocrine/metabolic 0.875 0.748 – 1.02 0.0963 191 1943 exclusion phecode
241.2 Nontoxic multinodular goiter Endocrine/metabolic 0.997 0.876 – 1.14 0.964 288 2851 exclusion phecode
242 Thyrotoxicosis with or without goiter Endocrine/metabolic 0.991 0.91 – 1.08 0.835 650 7632 exclusion phecode
242.1 Graves' disease Endocrine/metabolic 1 0.832 – 1.21 0.987 138 1899 exclusion phecode
242.2 Toxic multinodular goiter Endocrine/metabolic 0.844 0.601 – 1.19 0.33 34 367 exclusion phecode
242.3 Exophthalmos Endocrine/metabolic 1.13 0.805 – 1.59 0.481 39 556 exclusion phecode
244 Hypothyroidism Endocrine/metabolic 1.07 1.04 – 1.11 1.37e-06 5674 60173 exclusion phecode
244.1 Secondary hypothyroidism Endocrine/metabolic 1.1 0.995 – 1.23 0.063 435 4614 exclusion phecode
244.2 Acquired hypothyroidism Endocrine/metabolic 0.955 0.684 – 1.33 0.789 39 407 exclusion phecode
244.4 Hypothyroidism NOS Endocrine/metabolic 1.08 1.04 – 1.11 1.74e-06 5412 57706 exclusion phecode
245 Thyroiditis Endocrine/metabolic 1.02 0.846 – 1.24 0.802 132 1215 exclusion phecode
245.2 Chronic thyroiditis Endocrine/metabolic 1.06 0.853 – 1.32 0.589 102 945 exclusion phecode
245.21 Chronic lymphocytic thyroiditis Endocrine/metabolic 1.01 0.803 – 1.27 0.926 97 912 exclusion phecode
246 Other disorders of thyroid Endocrine/metabolic 0.996 0.838 – 1.18 0.962 165 1670 exclusion phecode
250 Diabetes mellitus Endocrine/metabolic 1.1 1.07 – 1.13 4.04e-11 6268 70032 exclusion phecode
250.1 Type 1 diabetes Endocrine/metabolic 1.07 1 – 1.15 0.0512 944 10431 exclusion phecode
250.11 Type 1 diabetes with ketoacidosis Endocrine/metabolic 1 0.802 – 1.26 0.968 93 973 exclusion phecode
250.12 Type 1 diabetes with renal manifestations Endocrine/metabolic 1.01 0.67 – 1.54 0.945 25 311 exclusion phecode
250.13 Type 1 diabetes with ophthalmic manifestations Endocrine/metabolic 1.1 0.935 – 1.3 0.245 167 1846 exclusion phecode
250.14 Type 1 diabetes with neurological manifestations Endocrine/metabolic 1.18 0.894 – 1.57 0.239 53 630 exclusion phecode
250.2 Type 2 diabetes Endocrine/metabolic 1.11 1.08 – 1.14 2.72e-12 5550 63639 exclusion phecode
250.21 Type 2 diabetes with ketoacidosis Endocrine/metabolic 1.07 0.771 – 1.5 0.672 42 396 exclusion phecode
250.22 Type 2 diabetes with renal manifestations Endocrine/metabolic 1.17 0.914 – 1.5 0.21 63 715 exclusion phecode
250.23 Type 2 diabetes with ophthalmic manifestations Endocrine/metabolic 1.15 1.02 – 1.29 0.0223 322 3629 exclusion phecode
250.24 Type 2 diabetes with neurological manifestations Endocrine/metabolic 1.15 0.975 – 1.36 0.0977 161 1838 exclusion phecode
250.4 Abnormal glucose Endocrine/metabolic 0.995 0.864 – 1.15 0.943 231 2664 exclusion phecode
250.41 Impaired fasting glucose Endocrine/metabolic 1.03 0.825 – 1.28 0.799 95 1012 exclusion phecode
250.42 Other abnormal glucose Endocrine/metabolic 0.973 0.811 – 1.17 0.767 135 1665 exclusion phecode
250.5 Glycosuria or Acetonuria Endocrine/metabolic 1.09 0.831 – 1.44 0.522 59 535 exclusion phecode
250.6 Polyneuropathy in diabetes Endocrine/metabolic 1.25 1.03 – 1.53 0.0259 113 1278 exclusion phecode
250.7 Diabetic retinopathy Endocrine/metabolic 1.09 0.99 – 1.21 0.0792 455 4880 exclusion phecode
251.1 Hypoglycemia Endocrine/metabolic 1.11 0.985 – 1.25 0.0861 320 3507 exclusion phecode
252 Disorders of parathyroid gland Endocrine/metabolic 1.06 0.947 – 1.19 0.3 359 3508 exclusion phecode
252.1 Hyperparathyroidism Endocrine/metabolic 1.06 0.934 – 1.2 0.377 320 3129 exclusion phecode
252.2 Hypoparathyroidism Endocrine/metabolic 1 0.776 – 1.3 0.971 62 581 exclusion phecode
253
Disorders of the pituitary gland and its
Disorders of the pituitary gland and its hypothalamic control
 Endocrine/metabolic 1.16 1.02 – 1.32 0.0254 262 2561 exclusion phecode
253.1 Pituitary hyperfunction Endocrine/metabolic 1.18 0.922 – 1.5 0.193 75 702 exclusion phecode
253.11 Acromegaly and gigantism Endocrine/metabolic 0.882 0.623 – 1.25 0.478 34 367 exclusion phecode
253.2 Pituitary hypofunction Endocrine/metabolic 1.23 0.985 – 1.52 0.0681 103 949 exclusion phecode
253.3 Diabetes insipidus Endocrine/metabolic 1.23 0.872 – 1.74 0.237 40 390 exclusion phecode
253.7 Other disorders of neurohypophysis Endocrine/metabolic 1.18 0.88 – 1.59 0.267 51 598 exclusion phecode
255 Disorders of adrenal glands Endocrine/metabolic 1.09 0.946 – 1.25 0.24 239 2564 exclusion phecode
255.1 Adrenal hyperfunction Endocrine/metabolic 1.16 0.9 – 1.5 0.252 71 767 exclusion phecode
255.11 Cushing's syndrome Endocrine/metabolic 1.33 0.956 – 1.85 0.0901 40 466 exclusion phecode
255.12 Hyperaldosteronism Endocrine/metabolic 0.938 0.639 – 1.38 0.742 32 296 exclusion phecode
255.2 Adrenal hypofunction Endocrine/metabolic 1.07 0.893 – 1.28 0.472 147 1442 exclusion phecode
255.21 Glucocorticoid deficiency Endocrine/metabolic 1.07 0.893 – 1.28 0.468 146 1438 exclusion phecode
256 Ovarian dysfunction Endocrine/metabolic 0.975 0.802 – 1.19 0.8 127 1088 exclusion phecode
256.4 Polycystic ovaries Endocrine/metabolic 0.947 0.771 – 1.16 0.605 111 958 exclusion phecode
257 Testicular dysfunction Endocrine/metabolic 1.17 0.892 – 1.53 0.257 58 568 exclusion phecode
257.1 Testicular hypofunction Endocrine/metabolic 1.1 0.836 – 1.46 0.483 54 538 exclusion phecode
258 Iatrogenic endocrine disorders Endocrine/metabolic 1.33 0.952 – 1.85 0.0945 41 379 exclusion phecode
259 Other endocrine disorders Endocrine/metabolic 0.922 0.694 – 1.22 0.574 55 588 exclusion phecode
260 Protein-calorie malnutrition Endocrine/metabolic 0.957 0.737 – 1.24 0.743 58 782 exclusion phecode
260.1 Cachexia Endocrine/metabolic 1.14 0.64 – 2.05 0.65 12 189 exclusion phecode
260.6 Anorexia Endocrine/metabolic 1.08 0.946 – 1.23 0.261 290 3133 exclusion phecode
261 Vitamin deficiency Endocrine/metabolic 1.05 0.946 – 1.17 0.353 425 4688 exclusion phecode
261.2 Vitamin B-complex deficiencies Endocrine/metabolic 1.08 0.944 – 1.24 0.253 242 2875 exclusion phecode
261.4 Vitamin D deficiency Endocrine/metabolic 0.986 0.843 – 1.15 0.858 189 1804 exclusion phecode
261.41 Rickets or osteomalacia Endocrine/metabolic 1.22 0.863 – 1.72 0.261 37 297 exclusion phecode
262 Mineral deficiency NEC Endocrine/metabolic 0.888 0.712 – 1.11 0.292 100 959 exclusion phecode
269 Proteinuria Endocrine/metabolic 1.16 0.942 – 1.43 0.16 100 1298 exclusion phecode
270
Disorders of protein plasma/amino-acid
Disorders of protein plasma/amino-acid transport and metabolism
 Endocrine/metabolic 1.23 0.996 – 1.52 0.0542 103 1089 exclusion phecode
270.3 Disorders of plasma protein metabolism Endocrine/metabolic 1.18 0.95 – 1.48 0.133 91 903 exclusion phecode
270.32 Paraproteinemia Endocrine/metabolic 1.23 0.931 – 1.62 0.147 61 659 exclusion phecode
270.33 Amyloidosis Endocrine/metabolic 0.959 0.697 – 1.32 0.795 44 412 exclusion phecode
270.35 Macroglobulinemia Endocrine/metabolic 1.01 0.703 – 1.46 0.944 34 268 exclusion phecode
271
Disorders of carbohydrate transport and
Disorders of carbohydrate transport and metabolism
 Endocrine/metabolic 0.899 0.683 – 1.18 0.444 65 618 exclusion phecode
271.3
Intestinal disaccharidase deficiencies and
Intestinal disaccharidase deficiencies and disaccharide malabsorption
 Endocrine/metabolic 0.927 0.684 – 1.26 0.626 55 538 exclusion phecode
272 Disorders of lipoid metabolism Endocrine/metabolic 1.07 1.05 – 1.09 1.03e-09 10844 91455 exclusion phecode
272.1 Hyperlipidemia Endocrine/metabolic 1.07 1.04 – 1.09 1.38e-09 10818 91373 exclusion phecode
272.11 Hypercholesterolemia Endocrine/metabolic 1.06 1.04 – 1.09 3.48e-08 10034 88404 exclusion phecode
272.12 Hyperglyceridemia Endocrine/metabolic 0.863 0.53 – 1.4 0.553 18 201 exclusion phecode
272.13 Mixed hyperlipidemia Endocrine/metabolic 1.08 0.79 – 1.48 0.62 47 617 exclusion phecode
272.9 Unspecified disorder of lipoid metabolism Endocrine/metabolic 1.08 0.836 – 1.4 0.551 61 761 exclusion phecode
274 Gout and other crystal arthropathies Endocrine/metabolic 1.22 1.14 – 1.3 1.14e-09 1106 13015 exclusion phecode
274.1 Gout Endocrine/metabolic 1.24 1.16 – 1.33 1.44e-09 903 10878 exclusion phecode
274.11 Gouty arthropathy Endocrine/metabolic 1.48 1.1 – 1.98 0.00856 44 394 exclusion phecode
274.2 Crystal arthropathies Endocrine/metabolic 1.13 0.984 – 1.31 0.0811 226 2322 exclusion phecode
274.21 Chondrocalcinosis Endocrine/metabolic 1.15 0.985 – 1.34 0.0765 198 2137 exclusion phecode
275 Disorders of mineral metabolism Endocrine/metabolic 1.05 0.972 – 1.14 0.201 701 7960 exclusion phecode
275.1 Disorders of iron metabolism Hematopoietic 1.03 0.884 – 1.19 0.744 212 2352 exclusion phecode
275.3 Disorders of magnesium metabolism Endocrine/metabolic 1.1 0.905 – 1.33 0.342 120 1408 exclusion phecode
275.5 Disorders of calcium/phosphorus metabolism Endocrine/metabolic 1.05 0.943 – 1.17 0.377 403 4653 exclusion phecode
275.53 Disorders of phosphorus metabolism Endocrine/metabolic 1.14 0.876 – 1.5 0.321 60 669 exclusion phecode
276
Disorders of fluid, electrolyte, and acid-base
Disorders of fluid, electrolyte, and acid-base balance
 Endocrine/metabolic 1.03 0.985 – 1.08 0.201 2361 27695 exclusion phecode
276.1 Electrolyte imbalance Endocrine/metabolic 0.994 0.937 – 1.05 0.833 1336 15500 exclusion phecode
276.11 Hyperosmolality and/or hypernatremia Endocrine/metabolic 0.879 0.684 – 1.13 0.31 77 907 exclusion phecode
276.12 Hyposmolality and/or hyponatremia Endocrine/metabolic 1.02 0.937 – 1.12 0.621 606 6930 exclusion phecode
276.13 Hyperpotassemia Endocrine/metabolic 1.08 0.955 – 1.22 0.221 297 3489 exclusion phecode
276.14 Hypopotassemia Endocrine/metabolic 0.944 0.856 – 1.04 0.246 476 5620 exclusion phecode
276.4 Acid-base balance disorder Endocrine/metabolic 1.05 0.929 – 1.18 0.463 326 4421 exclusion phecode
276.41 Acidosis Endocrine/metabolic 1.03 0.913 – 1.17 0.6 294 3993 exclusion phecode
276.42 Alkalosis Endocrine/metabolic 1.11 0.778 – 1.59 0.559 34 426 exclusion phecode
276.5 Hypovolemia Endocrine/metabolic 1.07 0.994 – 1.14 0.0739 939 10721 exclusion phecode
276.6 Fluid overload Endocrine/metabolic 1.04 0.868 – 1.24 0.698 147 1687 exclusion phecode
276.8 Polydipsia Endocrine/metabolic 1.08 0.798 – 1.47 0.608 47 531 exclusion phecode
277 Other disorders of metabolism Endocrine/metabolic 1.05 0.929 – 1.19 0.42 306 3440 exclusion phecode
277.4 Disorders of bilirubin excretion Endocrine/metabolic 1.08 0.907 – 1.28 0.39 163 1314 exclusion phecode
277.5 Other disorders of lipoid metabolism Endocrine/metabolic 1.03 0.808 – 1.32 0.792 70 840 exclusion phecode
277.51 Lipoprotein disorders Endocrine/metabolic 1.04 0.538 – 2.01 0.908 11 196 exclusion phecode
278 Overweight, obesity and other hyperalimentation Endocrine/metabolic 1.17 1.12 – 1.21 4.33e-17 3679 42786 exclusion phecode
278.1 Obesity Endocrine/metabolic 1.17 1.13 – 1.21 3.66e-17 3617 42120 exclusion phecode
278.3 Localized adiposity Endocrine/metabolic 0.886 0.616 – 1.27 0.514 30 363 exclusion phecode
278.4 Abnormal weight gain Endocrine/metabolic 1.05 0.72 – 1.55 0.784 27 286 exclusion phecode
279 Disorders involving the immune mechanism Endocrine/metabolic 0.951 0.765 – 1.18 0.651 92 948 exclusion phecode
279.1 Immunity deficiency Endocrine/metabolic 0.934 0.74 – 1.18 0.566 80 801 exclusion phecode
279.11 Deficiency of humoral immunity Endocrine/metabolic 0.814 0.61 – 1.08 0.16 50 536 exclusion phecode
279.7 Other immunological findings Endocrine/metabolic 1.22 0.982 – 1.51 0.0735 95 825 exclusion phecode
280 Iron deficiency anemias Hematopoietic 1.05 1.01 – 1.1 0.0114 3027 30054 exclusion phecode
280.1
Iron deficiency anemias, unspecified or not due
Iron deficiency anemias, unspecified or not due to blood loss
 Hematopoietic 1.05 1.01 – 1.09 0.0151 2917 28847 exclusion phecode
280.2
Iron deficiency anemia secondary to blood loss
Iron deficiency anemia secondary to blood loss (chronic)
 Hematopoietic 1 0.857 – 1.18 0.954 184 1859 exclusion phecode
281 Other deficiency anemia Hematopoietic 1.06 0.953 – 1.18 0.273 404 4412 exclusion phecode
281.1 Megaloblastic anemia Hematopoietic 1.06 0.947 – 1.18 0.32 391 4242 exclusion phecode
281.11 Pernicious anemia Hematopoietic 1.1 0.962 – 1.25 0.17 280 2994 exclusion phecode
281.12 Other vitamin B12 deficiency anemia Hematopoietic 0.947 0.737 – 1.22 0.671 72 736 exclusion phecode
281.13 Folate-deficiency anemia Hematopoietic 0.952 0.716 – 1.27 0.738 59 656 exclusion phecode
281.9 Deficiency anemias Hematopoietic 1.3 0.796 – 2.11 0.296 19 199 exclusion phecode
282 Hereditary hemolytic anemias Hematopoietic 1.47 1.09 – 1.98 0.0111 57 593 exclusion phecode
282.8 Other hemoglobinopathies Hematopoietic 1.15 0.699 – 1.9 0.581 19 214 exclusion phecode
282.9 Other hereditary hemolytic anemias Hematopoietic 1.47 1.03 – 2.09 0.0329 34 354 exclusion phecode
283 Acquired hemolytic anemias Hematopoietic 1.41 1.04 – 1.92 0.0269 54 525 exclusion phecode
283.1 Autoimmune hemolytic anemias Hematopoietic 1.59 1.14 – 2.23 0.00652 45 416 exclusion phecode
284 Aplastic anemia Hematopoietic 1.23 1.03 – 1.47 0.0196 145 1611 exclusion phecode
285 Other anemias Hematopoietic 1.05 1.02 – 1.09 0.00126 4529 47293 exclusion phecode
285.1 Acute posthemorrhagic anemia Hematopoietic 1.15 0.937 – 1.42 0.177 109 1087 exclusion phecode
285.2 Anemia of chronic disease Hematopoietic 1.15 1 – 1.32 0.0462 248 2696 exclusion phecode
285.22 Anemia in neoplastic disease Hematopoietic 1.07 0.901 – 1.27 0.444 160 1625 exclusion phecode
286 Coagulation defects Hematopoietic 1.06 0.94 – 1.19 0.345 335 3627 exclusion phecode
286.1 Congenital coagulation defects Hematopoietic 1.11 0.942 – 1.3 0.215 176 1862 exclusion phecode
286.11 Von willebrand's disease Hematopoietic 1.26 0.904 – 1.77 0.171 39 380 exclusion phecode
286.12
Congenital deficiency of other clotting factors
Congenital deficiency of other clotting factors (including factor VII)
 Hematopoietic 1.14 0.932 – 1.4 0.199 113 1229 exclusion phecode
286.13 Congenital factor VIII disorder Hematopoietic 1.11 0.695 – 1.76 0.671 19 260 exclusion phecode
286.5
Hemorrhagic disorder due to intrinsic
Hemorrhagic disorder due to intrinsic circulating anticoagulants
 Hematopoietic 0.813 0.535 – 1.24 0.332 25 325 exclusion phecode
286.7 Other and unspecified coagulation defects Hematopoietic 1.1 0.918 – 1.33 0.295 143 1531 exclusion phecode
287 Purpura and other hemorrhagic conditions Hematopoietic 1.03 0.94 – 1.12 0.556 595 6153 exclusion phecode
287.1 Spontaneous ecchymoses Hematopoietic 0.987 0.734 – 1.33 0.93 54 504 exclusion phecode
287.2 Allergic purpura Hematopoietic 0.927 0.568 – 1.51 0.761 20 195 exclusion phecode
287.3 Thrombocytopenia Hematopoietic 1.04 0.948 – 1.14 0.42 562 5764 exclusion phecode
287.31 Primary thrombocytopenia Hematopoietic 1.03 0.86 – 1.22 0.781 157 1605 exclusion phecode
287.32 Secondary thrombocytopenia Hematopoietic 0.968 0.649 – 1.44 0.874 26 288 exclusion phecode
288 Diseases of white blood cells Hematopoietic 0.956 0.902 – 1.01 0.126 1422 14614 exclusion phecode
288.1 Decreased white blood cell count Hematopoietic 0.967 0.908 – 1.03 0.286 1210 12307 exclusion phecode
288.11 Neutropenia Hematopoietic 0.966 0.907 – 1.03 0.273 1214 12337 exclusion phecode
288.3 Eosinophilia Hematopoietic 0.649 0.429 – 0.984 0.0418 29 270 exclusion phecode
289 Other diseases of blood and blood-forming organs Hematopoietic 1.06 0.934 – 1.2 0.383 304 3229 exclusion phecode
289.3
Personal history of diseases of blood and
Personal history of diseases of blood and blood-forming organs
 Hematopoietic 1.04 0.844 – 1.27 0.73 119 1113 exclusion phecode
289.4 Lymphadenitis Hematopoietic 1.1 1.02 – 1.19 0.00896 873 10116 exclusion phecode
289.5 Diseases of spleen Hematopoietic 0.987 0.839 – 1.16 0.878 172 1935 exclusion phecode
289.8 Polycythemia, secondary Hematopoietic 1.28 1 – 1.63 0.0472 75 1043 exclusion phecode
289.9 Abnormality of red blood cells Hematopoietic 1.09 0.72 – 1.64 0.696 25 325 exclusion phecode
290
Delirium dementia and amnestic and other
Delirium dementia and amnestic and other cognitive disorders
 Mental Disorders 1.11 1.01 – 1.21 0.0227 602 6883 exclusion phecode
290.1 Dementias Mental Disorders 1.1 0.984 – 1.24 0.0931 345 3512 exclusion phecode
290.11 Alzheimer's disease Mental Disorders 1.06 0.884 – 1.26 0.55 146 1551 exclusion phecode
290.16 Vascular dementia Mental Disorders 1.27 0.978 – 1.65 0.0726 63 659 exclusion phecode
290.2 Delirium due to conditions classified elsewhere Mental Disorders 1.15 0.982 – 1.34 0.0831 188 2302 exclusion phecode
290.3
Other persistent mental disorders due to
Other persistent mental disorders due to conditions classified elsewhere
 Mental Disorders 1.36 0.792 – 2.34 0.265 14 277 exclusion phecode
291
Other specified nonpsychotic and/or transient
Other specified nonpsychotic and/or transient mental disorders
 Mental Disorders 1.15 1.01 – 1.31 0.0325 282 3225 exclusion phecode
291.1
Transient mental disorders due to conditions
Transient mental disorders due to conditions classified elsewhere
 Mental Disorders 0.909 0.656 – 1.26 0.564 41 551 exclusion phecode
291.4
Specific nonpsychotic mental disorders due to
Specific nonpsychotic mental disorders due to brain damage
 Mental Disorders 1.16 0.928 – 1.45 0.191 95 1098 exclusion phecode
291.8 Alteration of consciousness Mental Disorders 1.2 1.02 – 1.43 0.0329 153 1638 exclusion phecode
292 Neurological disorders Mental Disorders 1.05 0.995 – 1.11 0.078 1554 17349 exclusion phecode
292.1 Aphasia/speech disturbance Mental Disorders 1.04 0.943 – 1.14 0.455 502 5692 exclusion phecode
292.2 Mild cognitive impairment Mental Disorders 1.28 0.976 – 1.68 0.074 64 701 exclusion phecode
292.3 Memory loss Mental Disorders 1.06 0.923 – 1.21 0.423 254 2646 exclusion phecode
292.4 Altered mental status Mental Disorders 1.05 0.966 – 1.13 0.268 711 7984 exclusion phecode
292.6 Hallucinations Mental Disorders 0.969 0.798 – 1.18 0.747 115 1169 exclusion phecode
293 Symptoms involving head and neck Mental Disorders 1.07 0.987 – 1.17 0.0978 641 7752 exclusion phecode
293.1
Swelling, mass, or lump in head and neck
Swelling, mass, or lump in head and neck [Space-occupying lesion, intracranial NOS]
 Mental Disorders 1.04 0.921 – 1.17 0.547 324 3545 exclusion phecode
295 Schizophrenia and other psychotic disorders Mental Disorders 1.03 0.897 – 1.19 0.654 237 3517 exclusion phecode
295.1 Schizophrenia Mental Disorders 0.915 0.769 – 1.09 0.318 150 2342 exclusion phecode
295.2 Paranoid disorders Mental Disorders 1.04 0.787 – 1.37 0.793 61 747 exclusion phecode
295.3 Psychosis Mental Disorders 1.34 1 – 1.8 0.0474 56 734 exclusion phecode
296 Mood disorders Mental Disorders 1.1 1.06 – 1.14 3.66e-08 4031 53381 exclusion phecode
296.1 Bipolar Mental Disorders 1.03 0.909 – 1.16 0.672 318 4506 exclusion phecode
296.2 Depression Mental Disorders 1.11 1.07 – 1.15 1.71e-09 3845 50779 exclusion phecode
296.22 Major depressive disorder Mental Disorders 1.18 0.975 – 1.43 0.0901 130 1508 exclusion phecode
297.2 Suicide or self-inflicted injury Mental Disorders 1.07 0.846 – 1.36 0.555 81 1358 exclusion phecode
300 Anxiety disorders Mental Disorders 1.04 1 – 1.09 0.0488 2456 29389 exclusion phecode
300.1 Anxiety disorder Mental Disorders 1.05 1 – 1.09 0.0498 2291 27155 exclusion phecode
300.11 Generalized anxiety disorder Mental Disorders 1.08 0.824 – 1.41 0.579 67 648 exclusion phecode
300.12 Agorophobia, social phobia, and panic disorder Mental Disorders 1.09 0.955 – 1.24 0.206 255 3058 exclusion phecode
300.13 Phobia Mental Disorders 0.935 0.792 – 1.1 0.426 180 2181 exclusion phecode
300.3 Obsessive-compulsive disorders Mental Disorders 1.04 0.776 – 1.4 0.789 57 578 exclusion phecode
300.4 Dysthymic disorder Mental Disorders 1.41 0.858 – 2.32 0.175 19 217 exclusion phecode
300.8 Acute reaction to stress Mental Disorders 0.849 0.613 – 1.18 0.323 40 531 exclusion phecode
300.9 Posttraumatic stress disorder Mental Disorders 1.1 0.776 – 1.57 0.584 32 489 exclusion phecode
301 Personality disorders Mental Disorders 1.14 0.91 – 1.42 0.26 95 1468 exclusion phecode
301.2 Antisocial/borderline personality disorder Mental Disorders 1.14 0.807 – 1.61 0.458 35 523 exclusion phecode
302 Sexual and gender identity disorders Mental Disorders 0.99 0.778 – 1.26 0.937 68 1069 exclusion phecode
303 Psychogenic and somatoform disorders Mental Disorders 1.06 0.908 – 1.24 0.449 188 1997 exclusion phecode
303.3 Psychogenic disorder Mental Disorders 1.04 0.864 – 1.26 0.671 134 1503 exclusion phecode
303.4 Somatoform disorder Mental Disorders 1.08 0.797 – 1.46 0.629 54 542 exclusion phecode
304 Adjustment reaction Mental Disorders 1.06 0.856 – 1.32 0.578 104 1310 exclusion phecode
305.2 Eating disorder Mental Disorders 1.06 0.777 – 1.46 0.696 47 403 exclusion phecode
306 Other mental disorder Mental Disorders 1.08 1.02 – 1.14 0.00793 1326 94770 exclusion phecode
306.9 Tension headache Mental Disorders 1.13 0.928 – 1.38 0.224 119 1378 exclusion phecode
313 Pervasive developmental disorders Mental Disorders 0.799 0.541 – 1.18 0.258 31 280 exclusion phecode
313.3 Autism Mental Disorders 0.785 0.481 – 1.28 0.332 22 193 exclusion phecode
315 Develomental delays and disorders Mental Disorders 1.18 0.96 – 1.45 0.115 108 1311 exclusion phecode
315.1 Learning disorder Mental Disorders 1.48 1.15 – 1.9 0.00248 79 629 exclusion phecode
315.2 Speech and language disorder Mental Disorders 1.28 0.789 – 2.06 0.321 19 302 exclusion phecode
316 Substance addiction and disorders Mental Disorders 1.1 1.03 – 1.17 0.00551 1035 21290 exclusion phecode
316.1 Polyneuropathy due to drugs Mental Disorders 0.956 0.618 – 1.48 0.84 20 230 exclusion phecode
317 Alcohol-related disorders Mental Disorders 1.05 1.01 – 1.09 0.00787 3092 50473 exclusion phecode
317.1 Alcoholism Mental Disorders 1.04 0.998 – 1.09 0.0625 2291 35291 exclusion phecode
317.11 Alcoholic liver damage Mental Disorders 1.2 1.02 – 1.4 0.0245 180 3312 exclusion phecode
318 Tobacco use disorder Mental Disorders 1.03 0.947 – 1.13 0.455 543 76332 exclusion phecode
320 Meningitis Neurological 1.15 0.975 – 1.35 0.0982 178 1778 exclusion phecode
323 Encephalitis Neurological 1.08 0.893 – 1.3 0.43 125 1352 exclusion phecode
323.2 Acute (transverse) myelitis Neurological 0.79 0.527 – 1.19 0.257 27 303 exclusion phecode
324 Other CNS infection and poliomyelitis Neurological 1.02 0.824 – 1.25 0.886 107 1158 exclusion phecode
327 Sleep disorders Neurological 1.12 1 – 1.25 0.0426 377 4381 exclusion phecode
327.3 Sleep apnea Neurological 1.11 1.05 – 1.18 0.000353 1390 16291 exclusion phecode
327.4 Insomnia Neurological 1.27 0.939 – 1.72 0.122 52 618 exclusion phecode
327.41 Organic or persistent insomnia Neurological 1.19 0.869 – 1.63 0.277 43 524 exclusion phecode
331 Other cerebral degenerations Neurological 1.1 0.985 – 1.22 0.0917 407 4192 exclusion phecode
331.1 Hydrocephalus Neurological 1.08 0.926 – 1.27 0.315 179 1902 exclusion phecode
331.9 Cerebral degeneration, unspecified Neurological 1.08 0.909 – 1.29 0.372 147 1548 exclusion phecode
332 Parkinson's disease Neurological 0.991 0.897 – 1.09 0.858 483 3973 exclusion phecode
333
Extrapyramidal disease and abnormal movement
Extrapyramidal disease and abnormal movement disorders
 Neurological 1.05 0.933 – 1.18 0.416 341 3533 exclusion phecode
333.1 Essential tremor Neurological 1.3 1.02 – 1.66 0.0358 76 871 exclusion phecode
333.2 Myoclonus Neurological 1 0.718 – 1.4 0.997 36 379 exclusion phecode
333.4 Torsion dystonia Neurological 0.943 0.761 – 1.17 0.588 111 1006 exclusion phecode
334 Degenerative disease of the spinal cord Neurological 1.1 1.01 – 1.2 0.0351 593 6753 exclusion phecode
334.1 Spinocerebellar disease Neurological 1.4 1.05 – 1.88 0.0216 50 423 exclusion phecode
334.2 Anterior horn cell disease Neurological 0.972 0.783 – 1.21 0.801 96 860 exclusion phecode
335 Multiple sclerosis Neurological 0.946 0.855 – 1.05 0.278 473 5596 exclusion phecode
337 Disorders of the autonomic nervous system Neurological 0.882 0.714 – 1.09 0.241 103 1004 exclusion phecode
337.1 Peripheral autonomic neuropathy Neurological 0.927 0.625 – 1.37 0.706 30 269 exclusion phecode
338 Pain Neurological 1.16 1.01 – 1.32 0.0372 260 3028 exclusion phecode
338.1 Acute pain Neurological 1.03 0.858 – 1.24 0.737 143 1507 exclusion phecode
338.2 Chronic pain Neurological 1.26 1.03 – 1.54 0.0217 118 1561 exclusion phecode
339 Other headache syndromes Neurological 1.1 1.06 – 1.15 1.33e-06 2976 31811 exclusion phecode
340 Migraine Neurological 1.03 0.969 – 1.1 0.328 1207 11984 exclusion phecode
340.1 Migrain with aura Neurological 1.26 0.986 – 1.61 0.0644 90 905 exclusion phecode
341
Other demyelinating diseases of central nervous
Other demyelinating diseases of central nervous system
 Neurological 0.964 0.75 – 1.24 0.771 74 1089 exclusion phecode
342 Hemiplegia Neurological 1.02 0.923 – 1.12 0.733 471 5556 exclusion phecode
343 Infantile cerebral palsy Neurological 1.14 0.9 – 1.45 0.273 79 597 exclusion phecode
344 Other paralytic syndromes Neurological 1.05 0.911 – 1.22 0.485 213 2545 exclusion phecode
345 Epilepsy, recurrent seizures, convulsions Neurological 1.08 1.03 – 1.14 0.00214 1870 19539 exclusion phecode
345.1 Epilepsy Neurological 1.09 0.97 – 1.22 0.148 340 3384 exclusion phecode
345.11 Generalized convulsive epilepsy Neurological 1.07 0.91 – 1.26 0.402 167 1721 exclusion phecode
345.12 Partial epilepsy Neurological 1.19 0.969 – 1.45 0.0981 111 1117 exclusion phecode
345.3 Convulsions Neurological 0.978 0.906 – 1.05 0.558 798 8679 exclusion phecode
346.1
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of skull and head
 Neurological 1.34 0.997 – 1.8 0.0528 48 552 exclusion phecode
348 Other conditions of brain Neurological 1.08 0.951 – 1.23 0.233 278 3018 exclusion phecode
348.2 Cerebral edema and compression of brain Neurological 1.16 0.932 – 1.43 0.187 103 1061 exclusion phecode
348.4 Cerebral cysts Neurological 0.97 0.739 – 1.27 0.823 61 511 exclusion phecode
348.7 Coma Neurological 0.994 0.82 – 1.2 0.952 127 1360 exclusion phecode
348.8 Encephalopathy, not elsewhere classified Neurological 1.15 0.905 – 1.46 0.252 77 964 exclusion phecode
348.9 Other conditions of brain, NOS Neurological 1.13 0.938 – 1.35 0.203 128 1494 exclusion phecode
349
Other and unspecified disorders of the nervous
Other and unspecified disorders of the nervous system
 Neurological 1.01 0.831 – 1.22 0.948 126 1335 exclusion phecode
350 Abnormal movement Neurological 1.08 1.01 – 1.16 0.0356 951 10155 exclusion phecode
350.1 Abnormal involuntary movements Neurological 1.22 1.08 – 1.37 0.00108 339 3363 exclusion phecode
350.2 Abnormality of gait Neurological 1.05 0.954 – 1.15 0.334 552 5987 exclusion phecode
350.3 Lack of coordination Neurological 0.963 0.798 – 1.16 0.691 126 1349 exclusion phecode
350.6 Disturbances of sensation of smell and taste Neurological 1.23 0.763 – 1.98 0.398 23 204 exclusion phecode
351 Other peripheral nerve disorders Neurological 1.09 1.06 – 1.13 4.65e-08 4529 50460 exclusion phecode
352 Disorders of other cranial nerves Neurological 1.07 0.97 – 1.18 0.181 515 5425 exclusion phecode
352.1 Trigeminal nerve disorders [CN5] Neurological 1.1 0.918 – 1.31 0.313 165 1900 exclusion phecode
352.2 Facial nerve disorders [CN7] Neurological 1.09 0.968 – 1.22 0.155 338 3409 exclusion phecode
353 Nerve root and plexus disorders Neurological 1 0.897 – 1.12 0.98 374 4298 exclusion phecode
353.1 Nerve plexus lesions Neurological 0.893 0.665 – 1.2 0.451 48 470 exclusion phecode
353.2 Nerve root lesions Neurological 0.9 0.542 – 1.5 0.685 21 212 exclusion phecode
356 Hereditary and idiopathic peripheral neuropathy Neurological 1.3 0.962 – 1.75 0.0878 50 552 exclusion phecode
357 Inflammatory and toxic neuropathy Neurological 1.04 0.942 – 1.15 0.435 482 5051 exclusion phecode
358 Myoneural disorders Neurological 0.976 0.761 – 1.25 0.846 77 740 exclusion phecode
358.1 Myasthenia gravis Neurological 0.921 0.716 – 1.18 0.518 73 689 exclusion phecode
359 Muscular dystrophies and other myopathies Neurological 0.951 0.812 – 1.12 0.538 178 1815 exclusion phecode
359.1 Muscular dystrophies Neurological 1.06 0.783 – 1.43 0.705 54 493 exclusion phecode
359.2 Myopathy Neurological 0.934 0.779 – 1.12 0.462 133 1419 exclusion phecode
360 Disorders of the globe Sense Organs 1.06 0.878 – 1.28 0.547 125 1312 exclusion phecode
360.2 Progressive myopia Sense Organs 0.973 0.782 – 1.21 0.807 92 948 exclusion phecode
361 Retinal detachments and defects Sense Organs 0.954 0.898 – 1.01 0.131 1240 11543 exclusion phecode
361.1 Retinal detachment with retinal defect Sense Organs 0.964 0.878 – 1.06 0.44 520 4919 exclusion phecode
361.2 Retinoschisis and retinal cysts Sense Organs 0.79 0.548 – 1.14 0.206 37 273 exclusion phecode
362 Other retinal disorders Sense Organs 1.02 0.962 – 1.08 0.517 1399 14316 exclusion phecode
362.2
Degeneration of macula and posterior pole of
Degeneration of macula and posterior pole of retina
 Sense Organs 1.08 1 – 1.17 0.0492 801 8314 exclusion phecode
362.29 Macular degeneration (senile) of retina NOS Sense Organs 1.08 1 – 1.17 0.0492 801 8297 exclusion phecode
362.3 Other nondiabetic retinopathy Sense Organs 0.86 0.655 – 1.13 0.278 55 574 exclusion phecode
362.31 Separation of retinal layers Sense Organs 0.951 0.671 – 1.35 0.78 33 368 exclusion phecode
362.4 Retinal vascular changes and abnomalities Sense Organs 0.983 0.87 – 1.11 0.79 304 3069 exclusion phecode
362.6 Peripheral retinal degenerations Sense Organs 1.04 0.803 – 1.34 0.774 71 655 exclusion phecode
362.7 Hereditary retinal dystrophies Sense Organs 0.974 0.704 – 1.35 0.872 41 323 exclusion phecode
362.8 Retinal hemorrhage/ischemia Sense Organs 0.999 0.705 – 1.42 0.996 38 420 exclusion phecode
363
Chorioretinal inflammations, scars, and other
Chorioretinal inflammations, scars, and other disorders of choroid
 Sense Organs 0.858 0.671 – 1.1 0.223 74 674 exclusion phecode
363.3 Chorioretinal scars Sense Organs 0.723 0.488 – 1.07 0.107 31 266 exclusion phecode
364 Corneal opacity and other disorders of cornea Sense Organs 0.949 0.831 – 1.09 0.445 255 2447 exclusion phecode
364.1 Corneal opacity Sense Organs 0.963 0.674 – 1.38 0.836 32 352 exclusion phecode
364.2 Corneal edema Sense Organs 0.94 0.651 – 1.36 0.741 28 290 exclusion phecode
364.4 Corneal degenerations Sense Organs 0.836 0.671 – 1.04 0.111 89 747 exclusion phecode
364.41 Keratoconus Sense Organs 0.722 0.533 – 0.979 0.0358 45 320 exclusion phecode
364.5 Corneal dystrophy Sense Organs 1.16 0.904 – 1.49 0.242 73 820 exclusion phecode
364.9 Cornea replaced by transplant Sense Organs 0.912 0.642 – 1.3 0.608 35 406 exclusion phecode
365 Glaucoma Sense Organs 1.03 0.98 – 1.09 0.222 1655 16267 exclusion phecode
365.1 Open-angle glaucoma Sense Organs 0.913 0.817 – 1.02 0.107 383 3690 exclusion phecode
365.11 Primary open angle glaucoma Sense Organs 0.913 0.817 – 1.02 0.109 379 3678 exclusion phecode
365.2 Primary angle-closure glaucoma Sense Organs 1.19 1.05 – 1.36 0.00734 286 2776 exclusion phecode
366 Cataract Sense Organs 1.02 0.995 – 1.05 0.119 7091 63159 exclusion phecode
366.1 Nonsenile Cataract Sense Organs 1.14 0.76 – 1.7 0.529 30 277 exclusion phecode
366.2 Senile cataract Sense Organs 1.05 1.01 – 1.09 0.0263 2876 31149 exclusion phecode
366.3 Traumatic cataract Sense Organs 1.03 0.742 – 1.44 0.846 34 384 exclusion phecode
367
Disorders of refraction and accommodation
Disorders of refraction and accommodation; blindness and low vision
 Sense Organs 1.03 0.955 – 1.1 0.477 889 9161 exclusion phecode
367.1 Myopia Sense Organs 1.01 0.914 – 1.12 0.823 461 4745 exclusion phecode
367.2 Astigmatism Sense Organs 0.944 0.747 – 1.19 0.63 84 737 exclusion phecode
367.8 Hypermetropia Sense Organs 1.42 1.12 – 1.79 0.00358 91 954 exclusion phecode
367.9 Blindness and low vision Sense Organs 1.02 0.891 – 1.16 0.79 256 2714 exclusion phecode
368 Visual disturbances Sense Organs 1.07 1 – 1.14 0.0447 1102 11462 exclusion phecode
368.1 Amblyopia Sense Organs 0.86 0.742 – 0.997 0.0452 198 1945 exclusion phecode
368.2 Diplopia and disorders of binocular vision Sense Organs 1.09 0.957 – 1.25 0.19 265 2793 exclusion phecode
368.3 Anisometropia Sense Organs 0.988 0.742 – 1.32 0.937 56 554 exclusion phecode
368.4 Visual field defects Sense Organs 1.1 0.898 – 1.35 0.35 107 1266 exclusion phecode
368.9 Subjective visual disturbances Sense Organs 1.2 1.04 – 1.38 0.0101 238 2509 exclusion phecode
369 Infection of the eye Sense Organs 0.896 0.771 – 1.04 0.15 218 2150 exclusion phecode
369.2 Eye infection, viral Sense Organs 0.728 0.524 – 1.01 0.0595 47 484 exclusion phecode
369.5 Conjunctivitis, infectious Sense Organs 0.852 0.667 – 1.09 0.197 82 811 exclusion phecode
370 Keratitis Sense Organs 1.09 0.887 – 1.34 0.416 110 1157 exclusion phecode
370.1 Corneal ulcer Sense Organs 1.11 0.835 – 1.48 0.467 54 553 exclusion phecode
371 Inflammation of the eye Sense Organs 1.03 0.963 – 1.09 0.423 1181 11912 exclusion phecode
371.1 Uveitis, noninfectious or NOS Sense Organs 0.911 0.772 – 1.08 0.274 167 1880 exclusion phecode
371.3 Inflammation of eyelids Sense Organs 1.05 0.978 – 1.13 0.175 948 9181 exclusion phecode
372 Disorders of conjunctiva Sense Organs 1.13 0.995 – 1.29 0.0604 280 2921 exclusion phecode
374 Other disorders of eyelids Sense Organs 1.03 0.983 – 1.08 0.214 2042 21978 exclusion phecode
374.1 Ectropion or entropion Sense Organs 1.03 0.916 – 1.15 0.647 358 3802 exclusion phecode
374.3 Ptosis of eyelid Sense Organs 1.05 0.968 – 1.14 0.232 689 7044 exclusion phecode
375 Disorders of lacrimal system Sense Organs 1.07 0.997 – 1.16 0.0599 887 8748 exclusion phecode
375.2 Epiphora Sense Organs 1.07 0.951 – 1.2 0.269 354 3495 exclusion phecode
376 Disorders of the orbit Sense Organs 1.01 0.704 – 1.44 0.967 36 334 exclusion phecode
377 Disorders of optic nerve and visual pathways Sense Organs 1.05 0.877 – 1.25 0.607 152 1460 exclusion phecode
377.1 Optic atrophy Sense Organs 1.13 0.732 – 1.74 0.586 25 213 exclusion phecode
377.3 Optic neuritis/neuropathy Sense Organs 0.872 0.655 – 1.16 0.348 55 534 exclusion phecode
378
Strabismus and other disorders of binocular eye
Strabismus and other disorders of binocular eye movements
 Sense Organs 1.01 0.918 – 1.1 0.89 556 5375 exclusion phecode
378.1 Strabismus (not specified as paralytic) Sense Organs 0.987 0.881 – 1.11 0.827 364 3499 exclusion phecode
378.2 Nystagmus and other irregular eye movements Sense Organs 1.12 0.892 – 1.41 0.328 90 809 exclusion phecode
378.5 Paralytic strabismus Sense Organs 0.844 0.676 – 1.05 0.136 101 1042 exclusion phecode
379 Other disorders of eye Sense Organs 1.05 0.99 – 1.12 0.102 1298 14063 exclusion phecode
379.2 Disorders of vitreous body Sense Organs 1.01 0.916 – 1.11 0.858 505 5064 exclusion phecode
379.3 Aphakia and other disorders of lens Sense Organs 1.14 1.04 – 1.24 0.00493 600 6877 exclusion phecode
379.4 Anomalies of pupillary function Sense Organs 1.28 0.885 – 1.84 0.191 31 283 exclusion phecode
379.5 Disorders of iris and ciliary body Sense Organs 1.06 0.888 – 1.26 0.541 152 1533 exclusion phecode
379.9 Pain, swelling or discharge of eye Sense Organs 0.973 0.749 – 1.26 0.837 62 686 exclusion phecode
380 Disorders of external ear Sense Organs 1.03 0.894 – 1.2 0.65 211 2485 exclusion phecode
380.1 Otitis externa Sense Organs 0.994 0.846 – 1.17 0.941 172 2105 exclusion phecode
380.4 Impacted cerumen Sense Organs 0.93 0.774 – 1.12 0.436 135 1381 exclusion phecode
381 Otitis media and Eustachian tube disorders Sense Organs 1.08 0.995 – 1.16 0.0654 759 8237 exclusion phecode
381.1 Otitis media Sense Organs 1.06 0.976 – 1.16 0.161 623 6719 exclusion phecode
381.11 Suppurative and unspecified otitis media Sense Organs 0.999 0.883 – 1.13 0.984 301 3285 exclusion phecode
381.2 Eustachian tube disorders Sense Organs 1.13 0.878 – 1.44 0.349 70 785 exclusion phecode
381.3 Mastoiditis & related conditions Sense Organs 1.08 0.84 – 1.4 0.536 70 672 exclusion phecode
381.9 Otorrhea Sense Organs 1.04 0.83 – 1.31 0.711 83 1088 exclusion phecode
382 Otalgia Sense Organs 1.02 0.835 – 1.26 0.814 122 1199 exclusion phecode
383 Otosclerosis Sense Organs 1.03 0.853 – 1.25 0.753 127 1244 exclusion phecode
384 Other disorders of tympanic membrane Sense Organs 1.18 1.07 – 1.31 0.00131 450 5009 exclusion phecode
384.4 Perforation of tympanic membrane Sense Organs 1.22 1.09 – 1.37 0.000543 367 3990 exclusion phecode
385 Other disorders of middle ear and mastoid Sense Organs 1.01 0.883 – 1.15 0.925 270 2943 exclusion phecode
385.3 Cholesteatoma Sense Organs 0.945 0.813 – 1.1 0.461 207 2223 exclusion phecode
385.5
Tympanosclerosis and middle ear disease related
Tympanosclerosis and middle ear disease related to otitis media
 Sense Organs 1.21 0.966 – 1.51 0.0979 92 943 exclusion phecode
386
Vertiginous syndromes and other disorders of
Vertiginous syndromes and other disorders of vestibular system
 Sense Organs 1.07 0.981 – 1.16 0.133 714 6740 exclusion phecode
386.1 Meniere's disease Sense Organs 1.01 0.878 – 1.17 0.862 239 2248 exclusion phecode
386.2 Peripheral or central vertigo Sense Organs 1.12 0.939 – 1.34 0.204 156 1392 exclusion phecode
386.3 Labyrinthitis Sense Organs 1.12 0.988 – 1.26 0.0772 329 3014 exclusion phecode
386.9
Dizziness and giddiness (Light-headedness and
Dizziness and giddiness (Light-headedness and vertigo)
 Sense Organs 1.08 1.02 – 1.14 0.00409 1754 17576 exclusion phecode
388 Other disorders of ear Sense Organs 0.894 0.706 – 1.13 0.352 78 773 exclusion phecode
389 Hearing loss Sense Organs 1.04 0.979 – 1.1 0.218 1483 15685 exclusion phecode
389.1 Sensorineural hearing loss Sense Organs 1.14 0.964 – 1.34 0.126 166 1729 exclusion phecode
389.2 Conductive hearing loss Sense Organs 1.24 1.04 – 1.46 0.0137 168 1784 exclusion phecode
389.4 Tinnitus Sense Organs 0.997 0.851 – 1.17 0.968 193 1905 exclusion phecode
394 Rheumatic disease of the heart valves Circulatory System 1.06 1.01 – 1.12 0.025 1636 17815 exclusion phecode
394.2 Mitral valve disease Circulatory System 1.01 0.948 – 1.08 0.69 1030 10947 exclusion phecode
394.3 Aortic valve disease Circulatory System 1.05 0.943 – 1.17 0.38 412 4574 exclusion phecode
394.7 Disease of tricuspid valve Circulatory System 1.04 0.934 – 1.17 0.442 358 3824 exclusion phecode
395 Heart valve disorders Circulatory System 1.03 0.97 – 1.09 0.37 1406 15276 exclusion phecode
395.1 Nonrheumatic mitral valve disorders Circulatory System 1.01 0.941 – 1.08 0.831 991 10561 exclusion phecode
395.2 Nonrheumatic aortic valve disorders Circulatory System 1.16 0.91 – 1.48 0.233 82 972 exclusion phecode
395.3 Nonrheumatic tricuspid valve disorders Circulatory System 1.04 0.761 – 1.43 0.798 41 394 exclusion phecode
395.4 Nonrheumatic pulmonary valve disorders Circulatory System 1.19 0.842 – 1.67 0.326 32 348 exclusion phecode
395.6 Heart valve replaced Circulatory System 1.04 0.941 – 1.14 0.462 476 5286 exclusion phecode
396 Abnormal heart sounds Circulatory System 1.03 0.929 – 1.14 0.57 440 4312 exclusion phecode
401 Hypertension Circulatory System 1.07 1.06 – 1.09 2.66e-21 25518 107621 exclusion phecode
401.1 Essential hypertension Circulatory System 1.07 1.06 – 1.09 2.44e-21 25453 107522 exclusion phecode
401.2 Hypertensive heart and/or renal disease Circulatory System 1.15 1.05 – 1.25 0.0027 570 7090 exclusion phecode
401.21 Hypertensive heart disease Circulatory System 1.43 1.16 – 1.77 0.00102 96 1359 exclusion phecode
401.22 Hypertensive chronic kidney disease Circulatory System 1.09 0.991 – 1.2 0.0769 477 5802 exclusion phecode
401.3 Other hypertensive complications Circulatory System 1.51 1.07 – 2.14 0.02 35 553 exclusion phecode
402
Elevated blood pressure reading without
Elevated blood pressure reading without diagnosis of hypertension
 Circulatory System 1.1 1.01 – 1.21 0.0334 552 5712 exclusion phecode
411 Ischemic Heart Disease Circulatory System 1.07 1.04 – 1.09 1.26e-08 9188 80944 exclusion phecode
411.1 Unstable angina (intermediate coronary syndrome) Circulatory System 1.1 1.04 – 1.17 0.000478 1439 19093 exclusion phecode
411.2 Myocardial infarction Circulatory System 1.08 1.04 – 1.12 0.000143 3094 40443 exclusion phecode
411.3 Angina pectoris Circulatory System 1.09 1.05 – 1.12 3.79e-07 4586 53391 exclusion phecode
411.4 Coronary atherosclerosis Circulatory System 1.05 1.02 – 1.08 0.000411 5639 57091 exclusion phecode
411.41 Aneurysm and dissection of heart Circulatory System 1.04 0.916 – 1.19 0.522 271 2640 exclusion phecode
411.8
Other chronic ischemic heart disease
Other chronic ischemic heart disease, unspecified
 Circulatory System 1.09 1.06 – 1.13 1.55e-07 4088 48138 exclusion phecode
411.9
Other acute and subacute forms of ischemic
Other acute and subacute forms of ischemic heart disease
 Circulatory System 1.1 0.98 – 1.23 0.106 341 4450 exclusion phecode
414 Other forms of chronic heart disease Circulatory System 1.01 0.917 – 1.11 0.884 500 6547 exclusion phecode
414.2 ASCVD Circulatory System 1.08 0.657 – 1.77 0.768 12 267 exclusion phecode
415 Pulmonary heart disease Circulatory System 1.07 1.01 – 1.12 0.022 1600 16666 exclusion phecode
415.11 Pulmonary embolism and infarction, acute Circulatory System 0.736 0.494 – 1.1 0.134 29 290 exclusion phecode
415.2 Chronic pulmonary heart disease Circulatory System 1 0.853 – 1.17 0.999 177 2189 exclusion phecode
415.21 Primary pulmonary hypertension Circulatory System 1.01 0.843 – 1.21 0.915 139 1655 exclusion phecode
416 Cardiomegaly Circulatory System 1.09 1.01 – 1.17 0.0211 870 9548 exclusion phecode
418 Nonspecific chest pain Circulatory System 1.07 1.05 – 1.09 5.69e-10 10113 105402 exclusion phecode
418.1 Precordial pain Circulatory System 1.09 1.03 – 1.16 0.00472 1305 13885 exclusion phecode
420 Carditis Circulatory System 1.04 0.956 – 1.12 0.381 704 7743 exclusion phecode
420.1 Myocarditis Circulatory System 1.36 0.956 – 1.93 0.0873 37 461 exclusion phecode
420.2 Pericarditis Circulatory System 1.03 0.926 – 1.14 0.61 421 4832 exclusion phecode
420.21 Acute pericarditis Circulatory System 1.15 0.895 – 1.48 0.272 69 832 exclusion phecode
420.22 Chronic pericarditis Circulatory System 1.23 0.887 – 1.71 0.214 37 427 exclusion phecode
420.3 Endocarditis Circulatory System 1.04 0.913 – 1.19 0.555 266 2703 exclusion phecode
425 Cardiomyopathy Circulatory System 1.13 1.02 – 1.25 0.0204 454 4582 exclusion phecode
425.1 Primary/intrinsic cardiomyopathies Circulatory System 1.15 1.04 – 1.28 0.00627 447 4465 exclusion phecode
425.11 Hypertrophic obstructive cardiomyopathy Circulatory System 1.14 0.852 – 1.54 0.372 56 504 exclusion phecode
425.12 Other hypertrophic cardiomyopathy Circulatory System 1.2 0.895 – 1.61 0.221 59 626 exclusion phecode
425.8 Other cardiomyopathy Circulatory System 1.24 0.703 – 2.2 0.453 15 186 exclusion phecode
426 Cardiac conduction disorders Circulatory System 1.07 1.02 – 1.12 0.00486 2239 24828 exclusion phecode
426.2 Atrioventricular [AV] block Circulatory System 1.07 0.985 – 1.16 0.107 664 7420 exclusion phecode
426.21 First degree AV block Circulatory System 1.1 0.98 – 1.25 0.104 320 3427 exclusion phecode
426.23 Second degree AV block Circulatory System 0.946 0.795 – 1.13 0.529 148 1550 exclusion phecode
426.24 Atrioventricular block, complete Circulatory System 0.983 0.841 – 1.15 0.835 170 2039 exclusion phecode
426.25 Other heart block Circulatory System 1.44 1.03 – 2.02 0.0324 41 453 exclusion phecode
426.3 Bundle branch block Circulatory System 1.03 0.963 – 1.1 0.406 1083 12204 exclusion phecode
426.31 Right bundle branch block Circulatory System 1.04 0.941 – 1.14 0.463 488 5383 exclusion phecode
426.32 Left bundle branch block Circulatory System 1.06 0.964 – 1.15 0.245 564 6503 exclusion phecode
426.4 Anomalous atrioventricular excitation Circulatory System 1.24 0.976 – 1.57 0.0789 80 928 exclusion phecode
426.8 Other cardiac conduction disorders Circulatory System 1.01 0.661 – 1.55 0.954 19 244 exclusion phecode
426.9 Cardiac pacemaker/device in situ Circulatory System 1.14 1.06 – 1.23 0.000502 792 8687 exclusion phecode
426.91 Cardiac pacemaker in situ Circulatory System 1.14 1.05 – 1.23 0.00134 740 7958 exclusion phecode
427 Cardiac dysrhythmias Circulatory System 1.04 1.02 – 1.06 0.00142 8219 78159 exclusion phecode
427.1 Paroxysmal tachycardia, unspecified Circulatory System 1.05 0.984 – 1.12 0.139 1095 12052 exclusion phecode
427.11 Paroxysmal supraventricular tachycardia Circulatory System 1.03 0.959 – 1.11 0.381 832 8998 exclusion phecode
427.12 Paroxysmal ventricular tachycardia Circulatory System 1.05 0.929 – 1.19 0.43 284 3357 exclusion phecode
427.2 Atrial fibrillation and flutter Circulatory System 1.04 1.01 – 1.07 0.0153 4745 48108 exclusion phecode
427.3 Other specified cardiac dysrhythmias Circulatory System 1.06 0.998 – 1.13 0.0597 1129 11549 exclusion phecode
427.4 Cardiac arrest and ventricular fibrillation Circulatory System 0.893 0.795 – 1 0.0575 318 4245 exclusion phecode
427.41 Ventricular fibrillation and flutter Circulatory System 0.843 0.687 – 1.03 0.102 98 1221 exclusion phecode
427.42 Cardiac arrest Circulatory System 0.936 0.823 – 1.06 0.314 260 3530 exclusion phecode
427.5 Arrhythmia (cardiac) NOS Circulatory System 1.01 0.892 – 1.14 0.906 303 3609 exclusion phecode
427.6 Premature beats Circulatory System 1.12 0.96 – 1.3 0.152 189 2035 exclusion phecode
427.61 Supraventricular premature beats Circulatory System 1.1 0.821 – 1.48 0.518 50 443 exclusion phecode
427.7 Tachycardia NOS Circulatory System 1.08 1 – 1.17 0.0492 731 8596 exclusion phecode
427.8 Sinoatrial node dysfunction (Bradycardia) Circulatory System 1.24 1.04 – 1.48 0.0151 163 1407 exclusion phecode
427.9 Palpitations Circulatory System 1.06 1.01 – 1.13 0.0295 1525 15377 exclusion phecode
428 Congestive heart failure; nonhypertensive Circulatory System 1.09 1.04 – 1.15 0.00119 1543 20061 exclusion phecode
428.1 Congestive heart failure (CHF) NOS Circulatory System 1.09 0.991 – 1.19 0.0775 539 7651 exclusion phecode
428.2 Heart failure NOS Circulatory System 1.1 1.04 – 1.17 0.00147 1227 15827 exclusion phecode
429
Ill-defined descriptions and complications of
Ill-defined descriptions and complications of heart disease
 Circulatory System 0.946 0.828 – 1.08 0.416 253 2690 exclusion phecode
429.1 Heart transplant/surgery Circulatory System 1.3 0.773 – 2.19 0.323 13 231 exclusion phecode
429.2 Abnormal function study of cardiovascular system Circulatory System 0.885 0.757 – 1.04 0.13 181 1921 exclusion phecode
429.3 Symptoms involving cardiovascular system Circulatory System 1.12 0.876 – 1.43 0.364 72 783 exclusion phecode
430 Intracranial hemorrhage Circulatory System 1.06 0.975 – 1.16 0.162 609 7151 exclusion phecode
430.1 Subarachnoid hemorrhage Circulatory System 1.01 0.876 – 1.16 0.919 244 3341 exclusion phecode
430.2 Intracerebral hemorrhage Circulatory System 1.09 0.952 – 1.24 0.222 259 2838 exclusion phecode
430.3 Subdural hemorrhage Circulatory System 1.03 0.84 – 1.26 0.779 103 934 exclusion phecode
433 Cerebrovascular disease Circulatory System 1.06 1.01 – 1.1 0.00758 2703 32008 exclusion phecode
433.1 Occlusion and stenosis of precerebral arteries Circulatory System 1.19 1.04 – 1.36 0.00891 256 4162 exclusion phecode
433.12 Cerebral atherosclerosis Circulatory System 1.13 0.885 – 1.44 0.331 78 813 exclusion phecode
433.2 Occlusion of cerebral arteries Circulatory System 1.03 0.974 – 1.1 0.273 1303 15396 exclusion phecode
433.21
Cerebral artery occlusion, with cerebral
Cerebral artery occlusion, with cerebral infarction
 Circulatory System 0.997 0.907 – 1.1 0.956 512 6058 exclusion phecode
433.3 Cerebral ischemia Circulatory System 1.02 0.952 – 1.1 0.545 888 10645 exclusion phecode
433.31 Transient cerebral ischemia Circulatory System 1.04 0.952 – 1.13 0.412 657 7775 exclusion phecode
433.5 Cerebral aneurysm Circulatory System 0.984 0.8 – 1.21 0.879 108 1628 exclusion phecode
433.8 Late effects of cerebrovascular disease Circulatory System 1.03 0.929 – 1.15 0.563 396 4796 exclusion phecode
440 Atherosclerosis Circulatory System 1.07 0.919 – 1.24 0.397 193 4936 exclusion phecode
440.1 Atherosclerosis of renal artery Circulatory System 0.727 0.45 – 1.17 0.193 20 434 exclusion phecode
440.2 Atherosclerosis of the extremities Circulatory System 1.21 0.963 – 1.52 0.101 79 2850 exclusion phecode
440.9 Atherosclerosis of aorta Circulatory System 1.24 0.911 – 1.7 0.17 46 1110 exclusion phecode
441 Vascular insufficiency of intestine Circulatory System 1.01 0.868 – 1.18 0.862 194 2433 exclusion phecode
441.1 Acute vascular insufficiency of intestine Circulatory System 0.932 0.75 – 1.16 0.525 95 1136 exclusion phecode
442 Other aneurysm Circulatory System 0.999 0.9 – 1.11 0.992 396 6566 exclusion phecode
442.1 Aortic aneurysm Circulatory System 0.972 0.856 – 1.1 0.666 256 5020 exclusion phecode
442.11 Abdominal aortic aneurysm Circulatory System 0.977 0.797 – 1.2 0.827 98 3144 exclusion phecode
442.2 Aneurysm of iliac artery Circulatory System 1.05 0.685 – 1.61 0.822 20 318 exclusion phecode
442.3 Aneurysm of artery of lower extremity Circulatory System 1.31 0.949 – 1.82 0.0994 41 615 exclusion phecode
442.4 Arterial dissection Circulatory System 0.994 0.622 – 1.59 0.98 22 217 exclusion phecode
442.8 Aneurysm of other specified artery Circulatory System 0.788 0.606 – 1.03 0.0768 69 736 exclusion phecode
443 Peripheral vascular disease Circulatory System 1.18 1.1 – 1.27 7.31e-06 842 14759 exclusion phecode
443.1 Raynaud's syndrome Circulatory System 1.21 1.08 – 1.35 0.000855 396 4663 exclusion phecode
443.7
Peripheral angiopathy in diseases classified
Peripheral angiopathy in diseases classified elsewhere
 Circulatory System 1.09 0.887 – 1.33 0.428 106 1424 exclusion phecode
443.8 Other specified peripheral vascular diseases Circulatory System 1.2 1.11 – 1.29 5.15e-06 764 13866 exclusion phecode
443.9 Peripheral vascular disease, unspecified Circulatory System 1.2 1.08 – 1.34 0.00062 379 9380 exclusion phecode
444 Arterial embolism and thrombosis Circulatory System 1.12 0.941 – 1.34 0.201 136 3394 exclusion phecode
444.1
Arterial embolism and thrombosis of lower
Arterial embolism and thrombosis of lower extremity artery
 Circulatory System 1.17 0.913 – 1.5 0.215 67 1958 exclusion phecode
446 Polyarteritis nodosa and allied conditions Circulatory System 0.983 0.869 – 1.11 0.78 315 3206 exclusion phecode
446.4 Wegener's granulomatosis Circulatory System 1.17 0.908 – 1.5 0.229 76 689 exclusion phecode
446.5 Giant cell arteritis Circulatory System 0.984 0.826 – 1.17 0.854 150 1582 exclusion phecode
446.9 Arteritis NOS Circulatory System 0.842 0.665 – 1.07 0.155 91 873 exclusion phecode
447 Other disorders of arteries and arterioles Circulatory System 1.02 0.883 – 1.18 0.774 205 4897 exclusion phecode
447.1 Stricture of artery Circulatory System 0.926 0.735 – 1.17 0.517 75 3085 exclusion phecode
448 Disease of capillaries Circulatory System 1.28 0.902 – 1.81 0.168 40 541 exclusion phecode
450 Noninfectious disorders of lymphatic channels Circulatory System 1.11 0.972 – 1.27 0.123 271 2786 exclusion phecode
451 Phlebitis and thrombophlebitis Circulatory System 1.07 1.01 – 1.13 0.0232 1478 14774 exclusion phecode
451.2
Phlebitis and thrombophlebitis of lower
Phlebitis and thrombophlebitis of lower extremities
 Circulatory System 1.07 1.01 – 1.13 0.0226 1392 13741 exclusion phecode
452 Other venous embolism and thrombosis Circulatory System 0.945 0.811 – 1.1 0.466 193 2206 exclusion phecode
454 Varicose veins Circulatory System 1.05 1.02 – 1.09 0.00252 4319 44774 exclusion phecode
454.1 Varicose veins of lower extremity Circulatory System 1.06 1.02 – 1.09 0.000638 4467 46144 exclusion phecode
454.11 Varicose veins of lower extremity, symptomtic Circulatory System 0.984 0.849 – 1.14 0.832 204 2506 exclusion phecode
455 Hemorrhoids Circulatory System 1.04 1.02 – 1.07 0.000472 8636 91147 exclusion phecode
456 Chronic venous insufficiency [CVI] Circulatory System 1.09 0.839 – 1.42 0.513 61 634 exclusion phecode
457
Encounter for long-term (current) use of
Encounter for long-term (current) use of anticoagulants, antithrombotics, aspirin
 Circulatory System 0.798 0.569 – 1.12 0.189 37 354 exclusion phecode
458 Hypotension Circulatory System 1.1 1.05 – 1.15 0.000161 2004 21625 exclusion phecode
458.1 Orthostatic hypotension Circulatory System 1.07 0.971 – 1.19 0.166 470 4828 exclusion phecode
458.2 Iatrogenic hypotension Circulatory System 1.23 0.96 – 1.57 0.103 77 887 exclusion phecode
458.9 Hypotension NOS Circulatory System 1.11 1.04 – 1.18 0.000886 1194 13205 exclusion phecode
459 Other disorders of circulatory system Circulatory System 1.03 0.998 – 1.06 0.0674 5313 60709 exclusion phecode
459.1 Hemorrhage NOS Circulatory System 0.992 0.743 – 1.32 0.954 52 519 exclusion phecode
459.9 Circulatory disease NEC Circulatory System 1.03 1 – 1.06 0.0535 5265 60137 exclusion phecode
464 Acute sinusitis Respiratory 1.29 0.987 – 1.69 0.0619 66 782 exclusion phecode
465
Acute upper respiratory infections of multiple
Acute upper respiratory infections of multiple or unspecified sites
 Respiratory 1.07 0.993 – 1.15 0.0757 835 8951 exclusion phecode
465.2 Acute pharyngitis Respiratory 1.1 0.976 – 1.25 0.118 312 3235 exclusion phecode
465.4 Acute laryngitis and tracheitis Respiratory 0.926 0.697 – 1.23 0.595 60 621 exclusion phecode
470 Septal Deviations/Turbinate Hypertrophy Respiratory 1.06 1 – 1.11 0.0336 1669 18150 exclusion phecode
471 Nasal polyps Respiratory 1.07 1.01 – 1.14 0.0249 1179 12255 exclusion phecode
472 Chronic pharyngitis and nasopharyngitis Respiratory 1.12 1 – 1.24 0.0456 393 3663 exclusion phecode
473 Diseases of the larynx and vocal cords Respiratory 1.12 1.04 – 1.22 0.00461 718 9891 exclusion phecode
473.1 Chronic laryngitis Respiratory 1.47 1.01 – 2.14 0.0446 33 410 exclusion phecode
473.3 Paralysis/spasm of vocal cords or larynx Respiratory 0.919 0.742 – 1.14 0.442 93 991 exclusion phecode
473.4 Voice disturbance Respiratory 1.1 0.973 – 1.24 0.128 305 4151 exclusion phecode
474 Acute and chronic tonsillitis Respiratory 1.02 0.937 – 1.11 0.634 640 7194 exclusion phecode
474.1 Acute tonsillitis Respiratory 1.01 0.872 – 1.17 0.876 211 2235 exclusion phecode
474.2 Chronic tonsillitis and adenoiditis Respiratory 0.996 0.894 – 1.11 0.935 411 4577 exclusion phecode
475 Chronic sinusitis Respiratory 1.14 1.06 – 1.22 0.000238 977 10071 exclusion phecode
476 Allergic rhinitis Respiratory 0.949 0.857 – 1.05 0.32 440 4181 exclusion phecode
477 Epistaxis or throat hemorrhage Respiratory 1.05 0.974 – 1.12 0.218 870 9128 exclusion phecode
478 Throat pain Respiratory 1.03 0.855 – 1.23 0.785 130 1520 exclusion phecode
479 Other upper respiratory disease Respiratory 1.07 1.01 – 1.13 0.0176 1468 15956 exclusion phecode
480 Pneumonia Respiratory 1.03 0.994 – 1.08 0.101 2916 38931 exclusion phecode
480.1 Bacterial pneumonia Respiratory 1.01 0.965 – 1.06 0.583 1880 25119 exclusion phecode
480.11 Pneumococcal pneumonia Respiratory 1.02 0.964 – 1.07 0.564 1639 22276 exclusion phecode
480.12 Pseudomonal pneumonia Respiratory 1.28 0.829 – 1.98 0.263 24 342 exclusion phecode
480.2 Viral pneumonia Respiratory 0.924 0.633 – 1.35 0.68 27 277 exclusion phecode
480.3 Pneumonia due to fungus (mycoses) Respiratory 0.983 0.666 – 1.45 0.932 26 380 exclusion phecode
480.5 Bronchopneumonia and lung abscess Respiratory 0.933 0.811 – 1.08 0.339 222 2965 exclusion phecode
481 Influenza Respiratory 1.21 0.989 – 1.47 0.0644 114 1322 exclusion phecode
483 Acute bronchitis and bronchiolitis Respiratory 1.12 0.858 – 1.47 0.4 56 754 exclusion phecode
495 Asthma Respiratory 1.08 1.06 – 1.11 2.09e-12 9620 101869 exclusion phecode
495.2 Asthma with exacerbation Respiratory 1.11 0.886 – 1.39 0.365 82 1039 exclusion phecode
496 Chronic airway obstruction Respiratory 1.1 1.05 – 1.16 0.000183 1627 39784 exclusion phecode
496.1 Emphysema Respiratory 1.01 0.844 – 1.2 0.93 129 6691 exclusion phecode
496.2 Chronic bronchitis Respiratory 1.05 0.923 – 1.2 0.45 249 11507 exclusion phecode
496.21 Obstructive chronic bronchitis Respiratory 1.03 0.885 – 1.2 0.71 183 10607 exclusion phecode
496.3 Bronchiectasis Respiratory 1.13 1.04 – 1.22 0.00327 706 7503 exclusion phecode
497 Bronchitis Respiratory 0.986 0.846 – 1.15 0.854 188 2525 exclusion phecode
500 Lung disease due to external agents Respiratory 1.23 0.963 – 1.56 0.0976 76 1435 exclusion phecode
500.1 Extrinsic allergic alveolitis Respiratory 1.34 0.915 – 1.96 0.134 33 298 exclusion phecode
500.2 Pneumoconiosis Respiratory 1.22 0.838 – 1.77 0.302 33 767 exclusion phecode
501 Pneumonitis due to inhalation of food or vomitus Respiratory 0.966 0.829 – 1.13 0.66 186 2427 exclusion phecode
502 Postinflammatory pulmonary fibrosis Respiratory 1 0.871 – 1.15 0.975 223 3446 exclusion phecode
503 Pulmonary congestion and hypostasis Respiratory 1.2 0.995 – 1.44 0.0566 131 1964 exclusion phecode
504 Other alveolar and parietoalveolar pneumonopathy Respiratory 1.24 0.981 – 1.57 0.0713 91 1247 exclusion phecode
505 Other pulmonary inflamation or edema Respiratory 1.42 0.865 – 2.34 0.166 23 220 exclusion phecode
506 Empyema and pneumothorax Respiratory 0.992 0.874 – 1.13 0.897 274 4212 exclusion phecode
507 Pleurisy; pleural effusion Respiratory 1.06 1.01 – 1.11 0.0149 2001 23829 exclusion phecode
508
Pulmonary collapse; interstitial and
Pulmonary collapse; interstitial and compensatory emphysema
 Respiratory 1.09 1 – 1.19 0.0418 616 7601 exclusion phecode
509 Respiratory failure, insufficiency, arrest Respiratory 0.964 0.885 – 1.05 0.409 593 9659 exclusion phecode
509.1 Respiratory failure Respiratory 0.99 0.895 – 1.09 0.842 438 7624 exclusion phecode
509.2 Respiratory insufficiency Respiratory 1.01 0.907 – 1.12 0.867 388 6742 exclusion phecode
509.5 Respiratory arrest Respiratory 0.94 0.709 – 1.25 0.669 51 557 exclusion phecode
509.8
Dependence on respirator [Ventilator] or
Dependence on respirator [Ventilator] or supplemental oxygen
 Respiratory 0.844 0.682 – 1.04 0.119 97 1491 exclusion phecode
510 Other diseases of lung Respiratory 1.05 0.889 – 1.23 0.592 168 2879 exclusion phecode
512 Other symptoms of respiratory system Respiratory 1.08 1.04 – 1.12 0.000162 3109 34933 exclusion phecode
512.1 Wheezing Respiratory 1.05 0.837 – 1.32 0.673 81 839 exclusion phecode
512.2 Painful respiration Respiratory 0.998 0.763 – 1.31 0.989 63 860 exclusion phecode
512.7 Shortness of breath Respiratory 1.11 1.05 – 1.16 4.32e-05 1953 22539 exclusion phecode
512.8 Cough Respiratory 1.03 0.962 – 1.1 0.411 1018 11121 exclusion phecode
512.9 Other dyspnea Respiratory 1.08 0.957 – 1.21 0.221 323 3506 exclusion phecode
513 Respiratory abnormalities Respiratory 1.12 0.961 – 1.31 0.147 201 2282 exclusion phecode
513.3 Hypoventilation Respiratory 1.03 0.675 – 1.56 0.9 26 310 exclusion phecode
513.4 Hyperventilation Respiratory 1.09 0.871 – 1.35 0.466 102 1105 exclusion phecode
513.8 Disorders of diaphragm Respiratory 1.28 0.934 – 1.76 0.123 47 511 exclusion phecode
514 Abnormal findings examination of lungs Respiratory 1.06 0.969 – 1.16 0.202 536 9167 exclusion phecode
516 Abnormal sputum Respiratory 1.08 0.987 – 1.19 0.0932 511 8004 exclusion phecode
516.1 Hemoptysis Respiratory 1.1 1 – 1.21 0.046 503 7778 exclusion phecode
519
Other diseases of respiratory system, not
Other diseases of respiratory system, not elsewhere classified
 Respiratory 1.05 1.01 – 1.09 0.0258 2958 35949 exclusion phecode
519.2 Respiratory complications Respiratory 1.14 0.884 – 1.48 0.305 67 1239 exclusion phecode
519.8 Other diseases of respiratory system, NEC Respiratory 1.05 1.01 – 1.1 0.0145 2797 33997 exclusion phecode
519.9
Symptoms involving respiratory system and other
Symptoms involving respiratory system and other chest symptoms
 Respiratory 0.918 0.76 – 1.11 0.379 130 1240 exclusion phecode
520 Disorders of tooth development Digestive 1.06 0.983 – 1.14 0.128 836 8253 exclusion phecode
520.1 Hereditary disturbances in tooth structure Digestive 0.951 0.554 – 1.63 0.856 15 218 exclusion phecode
520.2 Disturbances in tooth eruption Digestive 1.02 0.955 – 1.1 0.51 995 9619 exclusion phecode
521 Diseases of hard tissues of teeth Digestive 1.03 0.961 – 1.1 0.435 1079 12026 exclusion phecode
521.1 Dental caries Digestive 1.03 0.961 – 1.1 0.439 1071 12064 exclusion phecode
522 Diseases of pulp and periapical tissues Digestive 0.988 0.905 – 1.08 0.794 615 7109 exclusion phecode
522.5 Periapical abscess Digestive 1.02 0.917 – 1.14 0.712 414 4722 exclusion phecode
523 Gingival and periodontal diseases Digestive 1.08 0.992 – 1.18 0.0744 619 6831 exclusion phecode
523.1 Gingivitis Digestive 1.08 0.743 – 1.56 0.699 42 421 exclusion phecode
523.3 Periodontitis (acute or chronic) Digestive 1.05 0.94 – 1.16 0.412 436 4813 exclusion phecode
523.31 Acute periodontitis Digestive 1.1 0.956 – 1.26 0.185 243 2765 exclusion phecode
523.32 Chronic periodontitis Digestive 0.921 0.79 – 1.07 0.29 212 2262 exclusion phecode
524 Dentofacial anomalies, including malocclusion Digestive 1.1 0.912 – 1.33 0.315 137 1333 exclusion phecode
524.3 Anomalies of tooth position/malocclusion Digestive 1.11 0.919 – 1.35 0.272 130 1206 exclusion phecode
525
Other diseases of the teeth and supporting
Other diseases of the teeth and supporting structures
 Digestive 1.06 0.988 – 1.14 0.105 981 10567 exclusion phecode
525.2 Atrophy of edentulous alveolar ridge Digestive 1.28 0.868 – 1.89 0.212 27 263 exclusion phecode
526 Diseases of the jaws Digestive 1.03 0.913 – 1.16 0.631 325 3737 exclusion phecode
526.1 Cysts of the jaws Digestive 1.09 0.877 – 1.35 0.447 102 1245 exclusion phecode
526.3 Anomalies of jaw size/symmetry Digestive 1.23 0.808 – 1.86 0.337 26 243 exclusion phecode
526.4 Temporomandibular joint disorders Digestive 1.23 0.996 – 1.53 0.0547 97 1012 exclusion phecode
526.41 Temporomandibular joint disorder, unspecified Digestive 1.24 0.998 – 1.55 0.0522 94 994 exclusion phecode
526.5 Inflammatory conditions of jaw Digestive 0.847 0.594 – 1.21 0.36 31 429 exclusion phecode
526.9 Jaw disease NOS Digestive 0.877 0.693 – 1.11 0.274 84 976 exclusion phecode
527 Diseases of the salivary glands Digestive 1.13 0.983 – 1.31 0.084 226 2813 exclusion phecode
527.1 Hypertrophy of salivary gland Digestive 1.12 0.772 – 1.63 0.551 32 352 exclusion phecode
527.2 Sialoadenitis Digestive 1.08 0.88 – 1.32 0.462 108 1472 exclusion phecode
527.7 Disturbance of salivary secretion Digestive 1.29 0.837 – 2 0.247 21 234 exclusion phecode
527.8 Other specified diseases of the salivary glands Digestive 1.18 0.834 – 1.66 0.355 36 467 exclusion phecode
528
Diseases of the oral soft tissues, excluding
Diseases of the oral soft tissues, excluding lesions specific for gingiva and tongue
 Digestive 1.02 0.964 – 1.09 0.448 1334 15394 exclusion phecode
528.1 Stomatitis and mucositis Digestive 0.948 0.811 – 1.11 0.502 191 1809 exclusion phecode
528.11 Stomatitis and mucositis (ulcerative) Digestive 1 0.842 – 1.19 0.997 159 1493 exclusion phecode
528.12 Oral aphthae Digestive 0.793 0.547 – 1.15 0.221 33 345 exclusion phecode
528.3 Cellulitis and abscess of oral soft tissues Digestive 1.18 0.87 – 1.59 0.291 50 743 exclusion phecode
528.4 Cysts of oral soft tissues Digestive 1.25 0.887 – 1.75 0.204 42 509 exclusion phecode
528.41 Cyst of the salivary gland Digestive 1.23 0.848 – 1.77 0.278 35 387 exclusion phecode
528.5 Diseases of lips Digestive 0.993 0.866 – 1.14 0.924 248 2706 exclusion phecode
528.6 Leukoplakia of oral mucosa Digestive 1.01 0.801 – 1.28 0.916 91 1196 exclusion phecode
528.7 Sialolithiasis Digestive 0.962 0.771 – 1.2 0.736 95 1263 exclusion phecode
529 Diseases and other conditions of the tongue Digestive 1.09 0.982 – 1.22 0.103 424 4926 exclusion phecode
529.1 Glossitis Digestive 0.986 0.79 – 1.23 0.902 100 1169 exclusion phecode
530 Diseases of esophagus Digestive 1.07 1.05 – 1.09 1.26e-11 11804 109669 exclusion phecode
530.1 Esophagitis, GERD and related diseases Digestive 1.07 1.05 – 1.09 2.54e-10 11040 106772 exclusion phecode
530.11 GERD Digestive 1.07 1.05 – 1.1 6.1e-09 8116 88546 exclusion phecode
530.12 Ulcer of esophagus Digestive 1.02 0.969 – 1.07 0.433 1750 19410 exclusion phecode
530.14 Reflux esophagitis Digestive 1.11 1.07 – 1.15 1.03e-08 3646 40537 exclusion phecode
530.2 Esophageal bleeding (varices/hemorrhage) Digestive 1.06 0.966 – 1.15 0.23 577 6519 exclusion phecode
530.3 Stricture and stenosis of esophagus Digestive 1.09 1 – 1.19 0.0397 635 6920 exclusion phecode
530.5 Disorders of esophageal motility Digestive 1.07 0.938 – 1.23 0.299 245 2551 exclusion phecode
530.6 Diverticulum of esophagus, acquired Digestive 1.33 0.988 – 1.79 0.0602 52 536 exclusion phecode
530.7 Gastroesophageal laceration-hemorrhage syndrome Digestive 1.09 0.892 – 1.34 0.391 113 1331 exclusion phecode
530.9 Heartburn Digestive 1.17 1.08 – 1.26 7.17e-05 792 8337 exclusion phecode
531 Peptic ulcer (excl. esophageal) Digestive 1.1 1.05 – 1.15 2.06e-05 2218 26758 exclusion phecode
531.1 Hemorrhage from gastrointestinal ulcer Digestive 1.26 1.07 – 1.47 0.00438 188 2327 exclusion phecode
531.2 Gastric ulcer Digestive 1.1 1.04 – 1.17 0.000963 1324 15663 exclusion phecode
531.3 Duodenal ulcer Digestive 1.09 1.01 – 1.17 0.0178 898 11132 exclusion phecode
531.4 Peptic ulcer, site unspecified Digestive 1.03 0.842 – 1.25 0.785 117 1600 exclusion phecode
532 Dysphagia Digestive 1.08 1.03 – 1.13 0.000912 2382 25224 exclusion phecode
535 Gastritis and duodenitis Digestive 1.06 1.04 – 1.08 1.83e-07 9604 102418 exclusion phecode
535.1 Acute gastritis Digestive 1.01 0.904 – 1.12 0.924 404 4703 exclusion phecode
535.2 Atrophic gastritis Digestive 1.05 0.872 – 1.25 0.629 137 1378 exclusion phecode
535.6 Duodenitis Digestive 1.09 1.04 – 1.14 0.000109 2240 28909 exclusion phecode
535.8 Other specified gastritis Digestive 1.08 1.04 – 1.12 0.000163 2891 31775 exclusion phecode
535.9 Gastritis and duodenitis, NOS Digestive 1.39 0.989 – 1.96 0.0576 37 447 exclusion phecode
536.8
Dyspepsia and other specified disorders of
Dyspepsia and other specified disorders of function of stomach
 Digestive 1.07 0.855 – 1.33 0.573 89 1020 exclusion phecode
537 Other disorders of stomach and duodenum Digestive 1.09 1.02 – 1.16 0.0115 1166 13242 exclusion phecode
540 Appendiceal conditions Digestive 1.01 0.95 – 1.08 0.709 1176 12316 exclusion phecode
540.1 Appendicitis Digestive 1.03 0.964 – 1.1 0.378 1097 11561 exclusion phecode
540.11 Acute appendicitis Digestive 1.02 0.949 – 1.09 0.638 995 10302 exclusion phecode
550 Abdominal hernia Digestive 1.05 1.03 – 1.07 1.58e-07 16103 111235 exclusion phecode
550.1 Inguinal hernia Digestive 1.03 0.997 – 1.06 0.0734 5284 42552 exclusion phecode
550.2 Diaphragmatic hernia Digestive 1.06 1.04 – 1.09 4.47e-08 9759 93168 exclusion phecode
550.3 Femoral hernia Digestive 0.904 0.78 – 1.05 0.179 221 2669 exclusion phecode
550.4 Umbilical hernia Digestive 1.06 1 – 1.13 0.0472 1206 13558 exclusion phecode
550.5 Ventral hernia Digestive 1.07 1.01 – 1.15 0.0282 1132 13325 exclusion phecode
555
Inflammatory bowel disease and other
Inflammatory bowel disease and other gastroenteritis and colitis
 Digestive 1.04 0.978 – 1.1 0.23 1457 17554 exclusion phecode
555.1 Regional enteritis Digestive 1.08 0.984 – 1.18 0.106 569 6990 exclusion phecode
555.2 Ulcerative colitis Digestive 1.01 0.94 – 1.07 0.878 1050 12422 exclusion phecode
555.21 Ulcerative colitis (chronic) Digestive 1.01 0.854 – 1.18 0.948 167 2185 exclusion phecode
556 Ulceration of the lower GI tract Digestive 1.2 1.06 – 1.34 0.00266 357 4186 exclusion phecode
556.1 Ulceration of intestine Digestive 1.21 1.04 – 1.4 0.0123 218 2624 exclusion phecode
557 Intestinal malabsorption (non-celiac) Digestive 0.881 0.722 – 1.08 0.214 118 1162 exclusion phecode
557.1 Celiac disease Digestive 0.961 0.889 – 1.04 0.311 794 7497 exclusion phecode
558 Noninfectious gastroenteritis Digestive 1.03 1.01 – 1.07 0.0199 5718 62667 exclusion phecode
559 Ileostomy status Digestive 1.03 0.936 – 1.12 0.585 549 6265 exclusion phecode
560 Intestinal obstruction without mention of hernia Digestive 0.998 0.943 – 1.06 0.958 1392 15542 exclusion phecode
560.1 Paralytic ileus Digestive 1.1 0.941 – 1.3 0.223 167 2027 exclusion phecode
560.2 Impaction of intestine Digestive 1.14 0.93 – 1.39 0.211 104 1071 exclusion phecode
560.3 Peritoneal or intestinal adhesions Digestive 0.975 0.857 – 1.11 0.698 284 3305 exclusion phecode
560.4 Other intestinal obstruction Digestive 0.988 0.928 – 1.05 0.7 1196 13343 exclusion phecode
561 Symptoms involving digestive system Digestive 1.1 1.07 – 1.13 1.12e-11 6148 64179 exclusion phecode
561.1 Diarrhea Digestive 1.15 0.978 – 1.34 0.0923 176 1880 exclusion phecode
561.2 Flatulence Digestive 1.01 0.926 – 1.09 0.875 669 6826 exclusion phecode
562 Diverticulosis and diverticulitis Digestive 1.07 1.05 – 1.1 1.95e-09 9034 82424 exclusion phecode
562.1 Diverticulosis Digestive 1.07 1.05 – 1.1 2.78e-09 9023 82402 exclusion phecode
563 Constipation Digestive 1.07 1.03 – 1.11 0.000246 3726 41364 exclusion phecode
564 Functional digestive disorders Digestive 1.04 1.02 – 1.07 0.000768 7615 82801 exclusion phecode
564.1 Irritable Bowel Syndrome Digestive 1.05 1 – 1.1 0.0308 2209 23067 exclusion phecode
564.8
Abnormal findings on exam of gastrointestinal
Abnormal findings on exam of gastrointestinal tract/ abdominal area
 Digestive 1.11 1.02 – 1.21 0.0185 604 6584 exclusion phecode
564.9 Personal history of diseases of digestive system Digestive 1.04 1.01 – 1.07 0.0195 5038 58491 exclusion phecode
565 Anal and rectal conditions Digestive 1.04 1.01 – 1.07 0.0147 4653 56709 exclusion phecode
565.1 Anal and rectal polyp Digestive 1.03 0.986 – 1.08 0.175 2060 27593 exclusion phecode
567 Peritonitis and retroperitoneal infections Digestive 1.02 0.901 – 1.16 0.731 290 3516 exclusion phecode
568 Other disorders of peritoneum Digestive 1.06 0.997 – 1.13 0.0607 1191 13219 exclusion phecode
568.1
Peritoneal adhesions (postoperative)
Peritoneal adhesions (postoperative) (postinfection)
 Digestive 1.06 0.998 – 1.13 0.0589 1134 12548 exclusion phecode
569 Other disorders of intestine Digestive 1 0.947 – 1.06 0.93 1437 16346 exclusion phecode
569.1 Toxic gastroenteritis and colitis Digestive 1.18 0.91 – 1.53 0.21 64 560 exclusion phecode
569.2 Gastrointestinal complications Digestive 0.983 0.832 – 1.16 0.845 156 1893 exclusion phecode
571 Chronic liver disease and cirrhosis Digestive 1.09 1.02 – 1.17 0.0108 949 11451 exclusion phecode
571.5 Other chronic nonalcoholic liver disease Digestive 1.09 0.998 – 1.19 0.0547 580 6626 exclusion phecode
571.51 Cirrhosis of liver without mention of alcohol Digestive 0.879 0.641 – 1.2 0.423 38 392 exclusion phecode
571.6 Primary biliary cirrhosis Digestive 1.03 0.812 – 1.32 0.789 82 1072 exclusion phecode
571.8
Liver abscess and sequelae of chronic liver
Liver abscess and sequelae of chronic liver disease
 Digestive 1.13 0.995 – 1.28 0.059 288 3604 exclusion phecode
571.81 Portal hypertension Digestive 1.14 0.973 – 1.35 0.104 168 1993 exclusion phecode
572 Ascites (non malignant) Digestive 1.02 0.929 – 1.12 0.7 547 5834 exclusion phecode
573 Other disorders of liver Digestive 0.942 0.856 – 1.04 0.217 521 5754 exclusion phecode
573.2 Liver replaced by transplant Digestive 1.01 0.725 – 1.4 0.962 40 362 exclusion phecode
573.3 Hepatomegaly Digestive 1.25 0.989 – 1.58 0.0616 80 1104 exclusion phecode
573.5 Jaundice (not of newborn) Digestive 1.05 0.935 – 1.19 0.394 332 3310 exclusion phecode
573.7 Abnormal results of function study of liver Digestive 1.07 1.01 – 1.14 0.0219 1248 13475 exclusion phecode
573.9 Abnormal serum enzyme levels Digestive 0.832 0.631 – 1.1 0.196 56 822 exclusion phecode
574 Cholelithiasis and cholecystitis Digestive 1.09 1.06 – 1.12 9.97e-10 6192 63120 exclusion phecode
574.1 Cholelithiasis Digestive 1.09 1.05 – 1.12 4.89e-08 5428 54888 exclusion phecode
574.11 Cholelithiasis with acute cholecystitis Digestive 1.11 1.02 – 1.22 0.0228 574 5936 exclusion phecode
574.12 Cholelithiasis with other cholecystitis Digestive 1.09 1.04 – 1.14 0.000392 2201 22145 exclusion phecode
574.2 Calculus of bile duct Digestive 1.11 1.04 – 1.19 0.00275 972 10568 exclusion phecode
574.3 Cholecystitis without cholelithiasis Digestive 1.09 1.02 – 1.17 0.0137 1002 10999 exclusion phecode
575 Other biliary tract disease Digestive 1.07 1.01 – 1.13 0.0181 1479 15316 exclusion phecode
575.1 Cholangitis Digestive 1.02 0.868 – 1.19 0.843 183 1802 exclusion phecode
575.2 Obstruction of bile duct Digestive 1.16 1.02 – 1.32 0.0243 277 2903 exclusion phecode
575.6 Cholesterolosis of gallbladder Digestive 1.07 0.911 – 1.25 0.424 205 1869 exclusion phecode
575.7 Other disorders of gallbladder Digestive 1.06 0.965 – 1.16 0.229 554 5685 exclusion phecode
575.8 Other disorders of biliary tract Digestive 1.03 0.92 – 1.15 0.638 373 4188 exclusion phecode
575.9
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of biliary tract
 Digestive 1.15 0.948 – 1.39 0.158 116 1434 exclusion phecode
577 Diseases of pancreas Digestive 1.05 0.981 – 1.13 0.156 944 10234 exclusion phecode
577.1 Acute pancreatitis Digestive 1.09 1 – 1.18 0.0425 732 7711 exclusion phecode
577.2 Chronic pancreatitis Digestive 1.02 0.85 – 1.22 0.852 136 1885 exclusion phecode
577.3 Cyst and pseudocyst of pancreas Digestive 1.07 0.873 – 1.31 0.523 106 1390 exclusion phecode
578 Gastrointestinal hemorrhage Digestive 1.05 1.02 – 1.07 0.000325 7495 80360 exclusion phecode
578.1 Hematemesis Digestive 1.1 1.01 – 1.2 0.0358 577 7486 exclusion phecode
578.2 Blood in stool Digestive 1.06 0.982 – 1.14 0.139 857 9960 exclusion phecode
578.8 Hemorrhage of rectum and anus Digestive 1.05 1.01 – 1.08 0.00515 4919 51643 exclusion phecode
578.9 Hemorrhage of gastrointestinal tract Digestive 1.05 1 – 1.11 0.0454 1900 20334 exclusion phecode
579 Other symptoms involving abdomen and pelvis Digestive 1.03 0.943 – 1.13 0.494 575 6199 exclusion phecode
579.2 Splenomegaly Digestive 1.13 0.952 – 1.34 0.164 147 1592 exclusion phecode
579.8 Nonspecific abnormal findings in stool contents Digestive 0.999 0.916 – 1.09 0.975 613 6451 exclusion phecode
580 Nephritis; nephrosis; renal sclerosis Genitourinary 1.07 0.977 – 1.18 0.138 502 5744 exclusion phecode
580.1 Glomerulonephritis Genitourinary 1.16 1.04 – 1.3 0.0104 348 3934 exclusion phecode
580.11 Proliferative glomerulonephritis Genitourinary 1.37 0.912 – 2.05 0.13 28 245 exclusion phecode
580.12 Non-proliferative glomerulonephritis Genitourinary 1.03 0.769 – 1.37 0.861 52 549 exclusion phecode
580.14 Chronic glomerulonephritis, NOS Genitourinary 1.16 1.02 – 1.31 0.0279 281 3254 exclusion phecode
580.2
Nephrotic syndrome without mention of
Nephrotic syndrome without mention of glomerulonephritis
 Genitourinary 1.02 0.868 – 1.21 0.786 155 1728 exclusion phecode
580.3
Nephritis and nephropathy without mention of
Nephritis and nephropathy without mention of glomerulonephritis
 Genitourinary 1.04 0.813 – 1.34 0.74 70 925 exclusion phecode
580.32
Nephritis and nephropathy with pathological
Nephritis and nephropathy with pathological lesion
 Genitourinary 1 0.783 – 1.28 0.998 75 941 exclusion phecode
585 Renal failure Genitourinary 1.06 1.01 – 1.11 0.0164 2195 25450 exclusion phecode
585.1 Acute renal failure Genitourinary 1.04 0.985 – 1.11 0.144 1369 16434 exclusion phecode
585.2 Renal failure NOS Genitourinary 1.04 0.948 – 1.15 0.381 483 5310 exclusion phecode
585.3 Chronic renal failure [CKD] Genitourinary 1.12 1.04 – 1.21 0.00198 868 9686 exclusion phecode
585.31 Renal dialysis Genitourinary 1.21 1.03 – 1.41 0.0186 180 1861 exclusion phecode
586 Other disorders of the kidney and ureters Genitourinary 1 0.942 – 1.07 0.916 1120 12492 exclusion phecode
586.1 Anatomical abnormatilies of kidney and ureters Genitourinary 0.896 0.695 – 1.16 0.398 69 789 exclusion phecode
586.11 Small kidney Genitourinary 0.97 0.743 – 1.27 0.823 61 693 exclusion phecode
586.2 Cyst of kidney, acquired Genitourinary 1.05 0.941 – 1.16 0.405 406 4567 exclusion phecode
586.3 Vascular disorders of kidney/hypertrophy Genitourinary 0.835 0.532 – 1.31 0.432 19 304 exclusion phecode
586.4 Stricture/obstruction of ureter Genitourinary 1.03 0.916 – 1.16 0.606 324 3461 exclusion phecode
587 Kidney replaced by transpant Genitourinary 1.04 0.866 – 1.26 0.647 132 1367 exclusion phecode
588 Disorders resulting from impaired renal function Genitourinary 0.808 0.573 – 1.14 0.223 36 411 exclusion phecode
589 Abnormal results of function study of kidney Genitourinary 0.9 0.639 – 1.27 0.546 35 446 exclusion phecode
590 Pyelonephritis Genitourinary 1.14 1.03 – 1.26 0.00964 466 5488 exclusion phecode
591 Urinary tract infection Genitourinary 1.06 1.02 – 1.09 0.00079 4557 48269 exclusion phecode
592 Cystitis and urethritis Genitourinary 1.02 0.953 – 1.09 0.597 1082 11731 exclusion phecode
592.1 Cystitis Genitourinary 1 0.937 – 1.07 0.966 1067 11511 exclusion phecode
592.11 Acute cystitis Genitourinary 1.2 0.879 – 1.63 0.251 43 512 exclusion phecode
592.12 Chronic cystitis Genitourinary 0.973 0.86 – 1.1 0.656 305 3432 exclusion phecode
592.13 Chronic interstitial cystitis Genitourinary 0.878 0.71 – 1.09 0.231 112 1011 exclusion phecode
592.2 Urethritis and urethral syndrome Genitourinary 1.04 0.791 – 1.37 0.776 57 623 exclusion phecode
593 Hematuria Genitourinary 1.03 1 – 1.06 0.0442 5708 59932 exclusion phecode
594 Urinary calculus Genitourinary 1.06 1.02 – 1.11 0.00786 2295 23140 exclusion phecode
594.1 Calculus of kidney Genitourinary 1.04 0.98 – 1.11 0.184 1121 11622 exclusion phecode
594.2 Calculus of lower urinary tract Genitourinary 1.03 0.905 – 1.18 0.617 254 2538 exclusion phecode
594.3 Calculus of ureter Genitourinary 1.08 1.01 – 1.16 0.0273 877 8747 exclusion phecode
594.8 Renal colic Genitourinary 1.08 0.998 – 1.16 0.0574 768 7438 exclusion phecode
595 Hydronephrosis Genitourinary 1.05 0.968 – 1.14 0.247 723 7056 exclusion phecode
596 Other disorders of bladder Genitourinary 0.994 0.958 – 1.03 0.755 3309 34896 exclusion phecode
596.1 Bladder neck obstruction Genitourinary 0.996 0.917 – 1.08 0.925 666 6298 exclusion phecode
596.5 Functional disorders of bladder Genitourinary 1.08 0.988 – 1.18 0.091 567 6365 exclusion phecode
597 Other disorders of urethra and urinary tract Genitourinary 1.06 1 – 1.12 0.0512 1480 14618 exclusion phecode
597.1 Urethral stricture (not specified as infectious) Genitourinary 1.05 0.99 – 1.12 0.105 1256 12184 exclusion phecode
597.2 Urinary complications NEC Genitourinary 1.06 0.712 – 1.58 0.769 28 304 exclusion phecode
598 Abnormal findings on examination of urine Genitourinary 1.03 0.972 – 1.1 0.288 1202 12799 exclusion phecode
598.9
Other nonspecific findings on examination of
Other nonspecific findings on examination of urine
 Genitourinary 0.874 0.71 – 1.08 0.206 103 1119 exclusion phecode
599 Other symptoms/disorders or the urinary system Genitourinary 1.06 1.03 – 1.09 1.46e-05 6843 71868 exclusion phecode
599.1 Urinary obstruction Genitourinary 0.823 0.63 – 1.08 0.154 60 576 exclusion phecode
599.2 Retention of urine Genitourinary 0.994 0.95 – 1.04 0.79 2226 22837 exclusion phecode
599.3 Dysuria Genitourinary 1.02 0.923 – 1.14 0.646 417 4622 exclusion phecode
599.4 Urinary incontinence Genitourinary 1.07 1.03 – 1.11 0.000208 3480 36870 exclusion phecode
599.5 Frequency of urination and polyuria Genitourinary 1.07 1.01 – 1.13 0.0184 1484 15081 exclusion phecode
599.6 Oliguria and anuria Genitourinary 1.13 0.77 – 1.66 0.533 31 369 exclusion phecode
599.8 Other symptoms involving urinary system Genitourinary 1.03 0.7 – 1.51 0.888 29 238 exclusion phecode
599.9 Other abnormality of urination Genitourinary 1.06 0.973 – 1.15 0.192 667 6813 exclusion phecode
600 Hyperplasia of prostate Genitourinary 1.01 0.979 – 1.05 0.429 3475 27554 exclusion phecode
601 Inflammatory diseases of prostate Genitourinary 0.956 0.883 – 1.03 0.261 709 6729 exclusion phecode
601.1 Prostatitis Genitourinary 0.949 0.867 – 1.04 0.253 551 4940 exclusion phecode
601.11 Acute prostatitis Genitourinary 0.906 0.722 – 1.14 0.395 91 760 exclusion phecode
601.12 Chronic prostatitis Genitourinary 0.95 0.843 – 1.07 0.395 312 2846 exclusion phecode
601.3 Orchitis and epididymitis Genitourinary 1.52 0.961 – 2.4 0.0735 17 217 exclusion phecode
601.4 Balanoposthitis Genitourinary 1.05 0.844 – 1.3 0.682 92 956 exclusion phecode
601.8
Other inflammatory disorders of male genital
Other inflammatory disorders of male genital organs
 Genitourinary 0.943 0.751 – 1.18 0.61 88 1018 exclusion phecode
602 Other disorders of prostate Genitourinary 0.973 0.88 – 1.08 0.597 435 4154 exclusion phecode
603 Other disorders of testis Genitourinary 1.02 0.941 – 1.11 0.625 683 7271 exclusion phecode
603.1 Hydrocele Genitourinary 0.967 0.873 – 1.07 0.512 424 4371 exclusion phecode
604 Disorders of penis Genitourinary 1.02 0.957 – 1.09 0.546 1108 11237 exclusion phecode
604.1 Redundant prepuce and phimosis/BXO Genitourinary 1.02 0.956 – 1.1 0.489 939 9318 exclusion phecode
605 Erectile dysfunction [ED] Genitourinary 0.968 0.751 – 1.25 0.8 68 900 exclusion phecode
608 Other disorders of male genital organs Genitourinary 1.03 0.958 – 1.1 0.469 961 9451 exclusion phecode
609 Male infertility and abnormal spermatozoa Genitourinary 1.52 1.2 – 1.91 0.000466 79 684 exclusion phecode
609.1 Infertility, male Genitourinary 1.61 1.09 – 2.39 0.0165 32 261 exclusion phecode
609.2 Abnormal spermatozoa Genitourinary 1.45 1.11 – 1.9 0.00712 55 508 exclusion phecode
610 Benign mammary dysplasias Genitourinary 1.05 0.977 – 1.12 0.199 1059 10940 exclusion phecode
610.1 Cystic mastopathy Genitourinary 1.05 0.935 – 1.17 0.432 391 4089 exclusion phecode
610.2 Fibroadenosis of breast Genitourinary 1.13 0.935 – 1.38 0.201 134 1331 exclusion phecode
610.3 Fibrosclerosis of breast Genitourinary 1.14 0.92 – 1.41 0.235 112 1337 exclusion phecode
610.4 Benign neoplasm of breast Genitourinary 1.02 0.935 – 1.12 0.62 607 6147 exclusion phecode
610.8 Other specified benign mammary dysplasias Genitourinary 1.13 0.993 – 1.3 0.0633 290 3060 exclusion phecode
611 Abnormal findings on mammogram or breast exam Genitourinary 0.974 0.893 – 1.06 0.55 649 6744 exclusion phecode
611.1 Abnormal mammogram Genitourinary 1.09 0.705 – 1.68 0.702 22 231 exclusion phecode
611.3 Lump or mass in breast Genitourinary 0.969 0.887 – 1.06 0.488 630 6564 exclusion phecode
612
Breast conditions, congenital or relating to
Breast conditions, congenital or relating to hormones
 Genitourinary 1.04 0.928 – 1.17 0.501 362 3760 exclusion phecode
612.2 Hypertrophy of breast (Gynecomastia) Genitourinary 1.03 0.912 – 1.15 0.678 342 3555 exclusion phecode
612.3 Congenital anomalies of breast Genitourinary – 31 320 exclusion phecode
613 Other nonmalignant breast conditions Genitourinary 1.07 0.978 – 1.16 0.147 647 7231 exclusion phecode
613.1 Inflammatory disease of breast Genitourinary 1.1 0.961 – 1.26 0.165 265 3132 exclusion phecode
613.5 Mastodynia Genitourinary 1.31 0.875 – 1.97 0.188 30 332 exclusion phecode
613.7 Other signs and symptoms in breast Genitourinary – 296 3055 exclusion phecode
613.8 Other specified disorders of breast Genitourinary – 124 1440 exclusion phecode
613.9 Breast disorder NOS Genitourinary – 92 925 exclusion phecode
614 Inflammatory diseases of female pelvic organs Genitourinary 1.02 0.974 – 1.07 0.4 2369 25426 exclusion phecode
614.1
Pelvic peritoneal adhesions, female
Pelvic peritoneal adhesions, female (postoperative) (postinfection)
 Genitourinary 1.02 0.957 – 1.09 0.504 1081 11390 exclusion phecode
614.3 Pelvic inflammatory disease (PID) Genitourinary 0.986 0.871 – 1.12 0.82 321 3786 exclusion phecode
614.31 Acute inflammatory pelvic disease Genitourinary 1.02 0.64 – 1.63 0.931 22 262 exclusion phecode
614.32 Chronic inflammatory pelvic disease Genitourinary 1.06 0.881 – 1.28 0.53 145 1891 exclusion phecode
614.33 Pelvic inflammatory disease, NOS Genitourinary 0.873 0.725 – 1.05 0.153 141 1600 exclusion phecode
614.4 Inflammatory diseases of uterus, except cervix Genitourinary 0.974 0.801 – 1.18 0.787 131 1230 exclusion phecode
614.5
Inflammatory disease of cervix, vagina, and
Inflammatory disease of cervix, vagina, and vulva
 Genitourinary 1.03 0.965 – 1.11 0.34 1046 11387 exclusion phecode
614.51 Cervicitis and endocervicitis Genitourinary 0.962 0.876 – 1.06 0.413 568 5826 exclusion phecode
614.52 Vaginitis and vulvovaginitis Genitourinary 1.04 0.881 – 1.22 0.675 181 1857 exclusion phecode
614.53 Cyst or abscess of Bartholin's gland Genitourinary 1.09 0.963 – 1.24 0.171 314 3348 exclusion phecode
614.54 Abscess or ulceration of vulva Genitourinary 1.18 0.916 – 1.51 0.203 73 1206 exclusion phecode
615 Endometriosis Genitourinary 1.12 1.06 – 1.18 2.93e-05 1843 18054 exclusion phecode
617
Disorders secondary to childbirth, surgery
Disorders secondary to childbirth, surgery, trauma
 Genitourinary 0.946 0.771 – 1.16 0.599 115 1364 exclusion phecode
618 Genital prolapse Genitourinary 1.04 1.01 – 1.08 0.0074 5160 50543 exclusion phecode
618.1 Prolapse of vaginal walls Genitourinary 1.06 1.02 – 1.1 0.00368 3197 31982 exclusion phecode
618.2 Uterine/Uterovaginal prolapse Genitourinary 0.999 0.955 – 1.04 0.953 2439 23450 exclusion phecode
618.5 Prolapse of vaginal vault after hysterectomy Genitourinary 0.971 0.839 – 1.12 0.69 233 2250 exclusion phecode
618.6 Vaginal enterocele, congenital or acquired Genitourinary 1 0.881 – 1.14 0.969 297 2981 exclusion phecode
619 Noninflammatory female genital disorders Genitourinary 1.02 0.983 – 1.06 0.292 3784 38487 exclusion phecode
619.1
Noninflammatory disorders of ovary, fallopian
Noninflammatory disorders of ovary, fallopian tube, and broad ligament
 Genitourinary 0.98 0.867 – 1.11 0.751 324 3180 exclusion phecode
619.2 Disorders of uterus, NEC Genitourinary 0.965 0.91 – 1.02 0.227 1482 14593 exclusion phecode
619.3 Noninflammatory disorders of cervix Genitourinary 1.07 1 – 1.13 0.0448 1289 12593 exclusion phecode
619.4 Noninflammatory disorders of vagina Genitourinary 1.04 0.962 – 1.13 0.312 748 7865 exclusion phecode
619.5 Noninflammatory disorders of vulva and perineum Genitourinary 1.01 0.915 – 1.11 0.899 535 5927 exclusion phecode
620 Dysplasia of female genital organs Genitourinary 1.03 0.695 – 1.54 0.867 27 299 exclusion phecode
621 Endometrial hyperplasia Genitourinary 1.11 1 – 1.22 0.0496 501 4957 exclusion phecode
622 Polyp of female genital organs Genitourinary 1 0.97 – 1.03 0.913 4790 45430 exclusion phecode
622.1 Polyp of corpus uteri Genitourinary 0.995 0.958 – 1.03 0.787 3532 34125 exclusion phecode
622.2 Mucous polyp of cervix Genitourinary 1.04 0.987 – 1.1 0.137 1675 14857 exclusion phecode
623 Hypertrophy of female genital organs Genitourinary 1.03 0.94 – 1.13 0.53 605 5679 exclusion phecode
624 Symptoms involving female genital tract Genitourinary 0.946 0.843 – 1.06 0.345 363 3438 exclusion phecode
624.1 Dystrophy of female genital tract Genitourinary 0.886 0.716 – 1.1 0.264 109 1014 exclusion phecode
624.2 Atrophy of female genital tract Genitourinary 0.886 0.757 – 1.04 0.128 191 1845 exclusion phecode
624.9 stress incontinence, female Genitourinary 1.08 1.03 – 1.13 0.000588 2425 25429 exclusion phecode
625
Pain and other symptoms associated with female
Pain and other symptoms associated with female genital organs
 Genitourinary 1.08 1.01 – 1.15 0.0173 1238 12843 exclusion phecode
625.1 Dyspareunia Genitourinary 1.05 0.954 – 1.16 0.308 515 5319 exclusion phecode
626
Disorders of menstruation and other abnormal
Disorders of menstruation and other abnormal bleeding from female genital tract
 Genitourinary 1.07 1.04 – 1.1 3.4e-06 7178 50722 exclusion phecode
626.1 Irregular menstrual cycle/bleeding Genitourinary 1.07 1.04 – 1.1 3.15e-06 6269 48584 exclusion phecode
626.11 Absent or infrequent menstruation Genitourinary 1.32 0.96 – 1.8 0.0875 48 486 exclusion phecode
626.12 Excessive or frequent menstruation Genitourinary 1.07 1.04 – 1.11 4.24e-05 4270 40797 exclusion phecode
626.13 Irregular menstrual cycle Genitourinary 1.06 0.986 – 1.15 0.11 866 8783 exclusion phecode
626.14 Irregular menstrual bleeding Genitourinary 1.06 1 – 1.12 0.0387 1722 16950 exclusion phecode
626.2 Dysmenorrhea Genitourinary 1.11 1.02 – 1.21 0.014 715 8005 exclusion phecode
626.4 Premenstrual tension syndromes Genitourinary 1.21 0.903 – 1.63 0.199 57 690 exclusion phecode
626.8 Infertility, female Genitourinary 1.06 0.972 – 1.16 0.184 646 6174 exclusion phecode
627 Menopausal and postmenopausal disorders Genitourinary 1.03 0.993 – 1.06 0.127 4535 44804 exclusion phecode
627.1 Postmenopausal bleeding Genitourinary 1.03 0.989 – 1.06 0.169 3903 38949 exclusion phecode
627.2 Symptomatic menopause Genitourinary 0.91 0.698 – 1.19 0.483 77 801 exclusion phecode
627.3 Postmenopausal atrophic vaginitis Genitourinary 1.03 0.934 – 1.13 0.563 540 4725 exclusion phecode
627.4 Premenopausal menorrhagia Genitourinary 0.987 0.819 – 1.19 0.89 140 1391 exclusion phecode
628 Ovarian cyst Genitourinary 1.09 1.04 – 1.15 0.000301 2054 21028 exclusion phecode
634 Miscarriage; stillbirth Pregnancy Complications 0.979 0.933 – 1.03 0.391 2172 16790 exclusion phecode
634.1 Missed abortion/Hydatidiform mole Pregnancy Complications 0.962 0.872 – 1.06 0.439 509 5239 exclusion phecode
634.3 Ectopic pregnancy Pregnancy Complications 1.04 0.863 – 1.26 0.676 136 1530 exclusion phecode
635
Hemorrhage during pregnancy; childbirth and
Hemorrhage during pregnancy; childbirth and postpartum
 Pregnancy Complications 0.949 0.879 – 1.02 0.174 866 7906 exclusion phecode
635.2
Antepartum hemorrhage, abruptio placentae, and
Antepartum hemorrhage, abruptio placentae, and placenta previa
 Pregnancy Complications 0.934 0.832 – 1.05 0.248 366 3873 exclusion phecode
635.3 Placenta previa and abruptio placenta Pregnancy Complications 0.946 0.862 – 1.04 0.242 568 5611 exclusion phecode
636
Early or threatened labor; hemorrhage in early
Early or threatened labor; hemorrhage in early pregnancy
 Pregnancy Complications 1.03 0.957 – 1.1 0.468 1027 9077 exclusion phecode
636.2 Early onset of delivery Pregnancy Complications 0.934 0.816 – 1.07 0.319 267 2801 exclusion phecode
636.3 Hemorrhage in early pregnancy Pregnancy Complications 1.04 0.941 – 1.15 0.426 479 4879 exclusion phecode
638 Other high-risk pregnancy Pregnancy Complications 0.583 0.388 – 0.877 0.00965 29 323 exclusion phecode
642
Hypertension complicating pregnancy
Hypertension complicating pregnancy, childbirth, and the puerperium
 Pregnancy Complications 1.06 0.958 – 1.17 0.257 496 5008 exclusion phecode
642.1 Preeclampsia and eclampsia Pregnancy Complications 1.14 0.948 – 1.38 0.16 135 1373 exclusion phecode
643 Excessive vomiting in pregnancy Pregnancy Complications 0.927 0.748 – 1.15 0.492 108 946 exclusion phecode
643.1 Hyperemesis gravidarum Pregnancy Complications 1.04 0.812 – 1.33 0.76 82 666 exclusion phecode
645 Late pregnancy and failed induction Pregnancy Complications 1.02 0.925 – 1.12 0.708 524 5576 exclusion phecode
646 Other complications of pregnancy NEC Pregnancy Complications 1 0.934 – 1.08 0.918 930 9386 exclusion phecode
647
Infectious and parasitic complications
Infectious and parasitic complications affecting pregnancy
 Pregnancy Complications 0.697 0.468 – 1.04 0.0773 34 303 exclusion phecode
647.1
Infections of genitourinary tract during
Infections of genitourinary tract during pregnancy
 Pregnancy Complications 1.04 0.861 – 1.26 0.677 125 1258 exclusion phecode
649
Other conditions or status of the mother
Other conditions or status of the mother complicating pregnancy, childbirth, or the puerperium
 Pregnancy Complications 1.01 0.733 – 1.39 0.948 45 497 exclusion phecode
649.1
Diabetes or abnormal glucose tolerance
Diabetes or abnormal glucose tolerance complicating pregnancy
 Pregnancy Complications 1.16 0.916 – 1.46 0.222 94 871 exclusion phecode
650 Normal delivery Pregnancy Complications 0.997 0.924 – 1.08 0.941 856 8476 exclusion phecode
651 Multiple gestation Pregnancy Complications 1.04 0.867 – 1.25 0.658 146 1544 exclusion phecode
652
Malposition and malpresentation of fetus or
Malposition and malpresentation of fetus or obstruction
 Pregnancy Complications 0.95 0.876 – 1.03 0.217 753 7423 exclusion phecode
653
Problems associated with amniotic cavity and
Problems associated with amniotic cavity and membranes
 Pregnancy Complications 0.854 0.78 – 0.935 0.000646 602 6048 exclusion phecode
654
Other and unspecified complications of birth
Other and unspecified complications of birth; puerperium affecting management of mother
 Pregnancy Complications 0.722 0.469 – 1.11 0.138 29 330 exclusion phecode
655
Known or suspected fetal abnormality affecting
Known or suspected fetal abnormality affecting management of mother
 Pregnancy Complications 0.935 0.887 – 0.986 0.0135 1830 13414 exclusion phecode
656 Other perinatal conditions of fetus or newborn Pregnancy Complications 1.02 0.747 – 1.39 0.904 46 463 exclusion phecode
661 Fetal distress and abnormal forces of labor Pregnancy Complications 0.948 0.882 – 1.02 0.15 956 8419 exclusion phecode
663
Umbilical cord complications during labor and
Umbilical cord complications during labor and delivery
 Pregnancy Complications 1.02 0.884 – 1.18 0.771 236 2370 exclusion phecode
665 Obstetrical/birth trauma Pregnancy Complications 0.924 0.881 – 0.969 0.00115 2389 13511 exclusion phecode
669 Complications of labor and delivery NEC Pregnancy Complications 0.902 0.844 – 0.964 0.00252 1114 9615 exclusion phecode
671
Venous/cerebrovascular complications embolism
Venous/cerebrovascular complications embolism in pregnancy and the puerperium
 Pregnancy Complications 0.911 0.692 – 1.2 0.51 66 758 exclusion phecode
674 Other complications of the puerperium NEC Pregnancy Complications 1.06 0.861 – 1.3 0.583 118 1163 exclusion phecode
676
Other disorders of the breast associated with
Other disorders of the breast associated with childbirth and disorders of lactation
 Pregnancy Complications 1.05 0.702 – 1.56 0.82 32 288 exclusion phecode
679 Complications of in utero procedures Dermatologic 0.954 0.654 – 1.39 0.809 31 262 exclusion phecode
681 Superficial cellulitis and abscess Dermatologic 1.08 1.03 – 1.13 0.00051 2545 27582 exclusion phecode
681.1 Cellulitis and abscess of fingers/toes Dermatologic 1 0.869 – 1.15 0.996 221 2086 exclusion phecode
681.2 Cellulitis and abscess of face/neck Dermatologic 1.01 0.859 – 1.18 0.924 177 2094 exclusion phecode
681.3 Cellulitis and abscess of arm/hand Dermatologic 1.1 1.04 – 1.15 0.000299 1900 20785 exclusion phecode
681.5 Cellulitis and abscess of leg, except foot Dermatologic 1.1 1.04 – 1.15 0.000224 1911 20789 exclusion phecode
681.6 Cellulitis and abscess of foot, toe Dermatologic 1.1 1.04 – 1.15 0.00029 1892 20618 exclusion phecode
681.7 Cellulitis and abscess of trunk Dermatologic 1.05 0.906 – 1.21 0.536 224 2405 exclusion phecode
686
Other local infections of skin and subcutaneous
Other local infections of skin and subcutaneous tissue
 Dermatologic 1.09 0.988 – 1.21 0.0845 472 5198 exclusion phecode
686.1 Carbuncle and furuncle Dermatologic 0.991 0.916 – 1.07 0.814 727 8934 exclusion phecode
686.3 Pilonidal cyst Dermatologic 1.15 0.971 – 1.36 0.106 159 2278 exclusion phecode
686.4 Pyogenic granuloma Dermatologic 1.04 0.878 – 1.24 0.641 162 1378 exclusion phecode
687 Symptoms affecting skin Dermatologic 0.982 0.842 – 1.15 0.815 198 2063 exclusion phecode
687.1 Rash and other nonspecific skin eruption Dermatologic 1.04 0.963 – 1.12 0.313 793 8354 exclusion phecode
687.2 Localized superficial swelling, mass, or lump Dermatologic 1.07 0.864 – 1.32 0.542 105 1090 exclusion phecode
687.3 Changes in skin texture Dermatologic 0.876 0.619 – 1.24 0.456 41 409 exclusion phecode
687.4 Disturbance of skin sensation Dermatologic 1.05 0.983 – 1.12 0.145 1072 11502 exclusion phecode
689 Disorder of skin and subcutaneous tissue NOS Dermatologic 1.02 0.974 – 1.07 0.383 2158 22321 exclusion phecode
690 Erythematosquamous dermatosis Dermatologic 1.12 0.732 – 1.72 0.598 22 264 exclusion phecode
690.1 Seborrheic dermatitis Dermatologic 1.12 0.689 – 1.84 0.638 17 196 exclusion phecode
691 Congenital anomalies of skin Dermatologic 1.15 0.846 – 1.57 0.37 50 449 exclusion phecode
694 Dyschromia and Vitiligo Dermatologic 1.04 0.932 – 1.16 0.487 405 3830 exclusion phecode
694.1 Vitiligo Dermatologic 0.948 0.6 – 1.5 0.818 27 240 exclusion phecode
694.2 Other dyschromia Dermatologic 1.03 0.912 – 1.17 0.62 317 3098 exclusion phecode
694.3 Vascular disorders of skin Dermatologic 0.931 0.687 – 1.26 0.643 50 418 exclusion phecode
695 Erythematous conditions Dermatologic 1.04 0.968 – 1.12 0.281 898 9548 exclusion phecode
695.1 Toxic erythema Dermatologic 1.01 0.713 – 1.43 0.952 36 432 exclusion phecode
695.2 Bullous dermatoses Dermatologic 1.01 0.739 – 1.37 0.967 43 518 exclusion phecode
695.21 Dermatitis herpetiformis Dermatologic 0.67 0.403 – 1.12 0.124 15 210 exclusion phecode
695.22 Pemphigus and pemphigoid Dermatologic 1.08 0.73 – 1.59 0.708 27 293 exclusion phecode
695.3 Rosacea Dermatologic 1.17 0.959 – 1.42 0.123 119 1177 exclusion phecode
695.4 Lupus (localized and systemic) Dermatologic 1.07 0.892 – 1.27 0.483 159 1766 exclusion phecode
695.41 Cutaneous lupus erythematosus Dermatologic 1.03 0.728 – 1.47 0.851 42 566 exclusion phecode
695.42 Systemic lupus erythematosus Dermatologic 1.08 0.891 – 1.3 0.443 138 1480 exclusion phecode
695.7 Prurigo and Lichen Dermatologic 1.06 0.938 – 1.2 0.342 294 3133 exclusion phecode
695.8 Other specified erythematous conditions Dermatologic 1.04 0.828 – 1.31 0.732 91 988 exclusion phecode
695.81 Erythema nodosum Dermatologic 0.864 0.594 – 1.26 0.443 31 314 exclusion phecode
695.9 Unspecified erythematous condition Dermatologic 1 0.856 – 1.17 0.988 188 1805 exclusion phecode
696 Psoriasis and related disorders Dermatologic 1.04 0.958 – 1.13 0.342 647 8661 exclusion phecode
696.4 Psoriasis Dermatologic 1.04 0.952 – 1.13 0.415 633 8471 exclusion phecode
696.41 Psoriasis vulgaris Dermatologic 1.03 0.93 – 1.14 0.592 442 6443 exclusion phecode
696.42 Psoriatic arthropathy Dermatologic 1.07 0.927 – 1.22 0.374 242 2783 exclusion phecode
697 Sarcoidosis Dermatologic 1.06 0.928 – 1.22 0.373 259 2129 exclusion phecode
698 Pruritus and related conditions Dermatologic 0.984 0.865 – 1.12 0.807 286 3056 exclusion phecode
700 Corns and callosities Dermatologic 1.41 1.13 – 1.77 0.00252 99 1234 exclusion phecode
701
Other hypertrophic and atrophic conditions of
Other hypertrophic and atrophic conditions of skin
 Dermatologic 1.05 0.995 – 1.1 0.074 1752 18530 exclusion phecode
701.1 Keratoderma, acquired Dermatologic 0.94 0.651 – 1.36 0.74 33 330 exclusion phecode
701.2 Scar conditions and fibrosis of skin Dermatologic 1.1 1.02 – 1.18 0.0125 886 9336 exclusion phecode
701.3 Circumscribed scleroderma Dermatologic 0.722 0.44 – 1.19 0.198 17 270 exclusion phecode
701.4 Keloid scar Dermatologic 1.05 0.825 – 1.34 0.695 85 928 exclusion phecode
701.5 Abnormal granulation tissue Dermatologic 0.987 0.84 – 1.16 0.876 185 1830 exclusion phecode
701.6 Acquired acanthosis nigricans Dermatologic 1.17 0.819 – 1.67 0.387 37 376 exclusion phecode
702
Degenerative skin conditions and other
Degenerative skin conditions and other dermatoses
 Dermatologic 1.03 0.978 – 1.08 0.297 2092 20624 exclusion phecode
702.1 Actinic keratosis Dermatologic 1.01 0.946 – 1.09 0.692 993 9713 exclusion phecode
702.2 Seborrheic keratosis Dermatologic 1.03 0.964 – 1.09 0.414 1175 11627 exclusion phecode
703 Diseases of nail, NOS Dermatologic 1.15 0.95 – 1.38 0.155 130 1371 exclusion phecode
703.1 Ingrowing nail Dermatologic 1.05 0.937 – 1.17 0.403 378 3807 exclusion phecode
704 Diseases of hair and hair follicles Dermatologic 1.06 1.01 – 1.11 0.0228 1865 20586 exclusion phecode
704.1 Alopecia Dermatologic 0.867 0.64 – 1.17 0.357 54 524 exclusion phecode
704.8
Other specified diseases of hair and hair
Other specified diseases of hair and hair follicles
 Dermatologic 1.22 0.819 – 1.8 0.333 32 296 exclusion phecode
705 Disorders of sweat glands Dermatologic 0.88 0.642 – 1.2 0.423 38 979 exclusion phecode
705.3 Hidradenitis Dermatologic 0.931 0.634 – 1.37 0.718 26 810 exclusion phecode
705.8 Hyperhidrosis Dermatologic 1.09 0.938 – 1.27 0.262 198 2246 exclusion phecode
706 Diseases of sebaceous glands Dermatologic 1.05 1.01 – 1.09 0.0213 2890 32610 exclusion phecode
706.1 Acne Dermatologic 1.12 0.762 – 1.66 0.556 30 307 exclusion phecode
706.2 Sebaceous cyst Dermatologic 1.04 1 – 1.09 0.0272 3065 34439 exclusion phecode
707 Chronic ulcer of skin Dermatologic 1.03 0.949 – 1.13 0.44 606 7266 exclusion phecode
707.1 Decubitus ulcer Dermatologic 1.15 1.01 – 1.31 0.0293 264 3340 exclusion phecode
709 Diffuse diseases of connective tissue Dermatologic 1.1 1.03 – 1.17 0.00235 1302 13710 exclusion phecode
709.2 Sicca syndrome Dermatologic 1.13 0.976 – 1.32 0.0995 223 2097 exclusion phecode
709.3 Systemic sclerosis Dermatologic 1.04 0.793 – 1.36 0.775 66 738 exclusion phecode
709.6
Other specified diffuse diseases of connective
Other specified diffuse diseases of connective tissue
 Dermatologic 0.975 0.668 – 1.42 0.896 29 278 exclusion phecode
709.7 Unspecified diffuse connective tissue disease Dermatologic 1.08 1.01 – 1.16 0.023 1010 10791 exclusion phecode
710
Osteomyelitis, periostitis, and other
Osteomyelitis, periostitis, and other infections involving bone
 Musculoskeletal 1.01 0.862 – 1.18 0.919 186 2243 exclusion phecode
710.1 Osteomyelitis Musculoskeletal 0.985 0.838 – 1.16 0.85 175 2070 exclusion phecode
710.12 Chronic osteomyelitis Musculoskeletal 1.15 0.883 – 1.5 0.301 58 718 exclusion phecode
710.19 Unspecified osteomyelitis Musculoskeletal 0.994 0.824 – 1.2 0.952 131 1469 exclusion phecode
711 Arthropathy associated with infections Musculoskeletal 1.13 0.948 – 1.34 0.176 163 1549 exclusion phecode
711.1 Pyogenic arthritis Musculoskeletal 1.33 1.09 – 1.63 0.00528 122 1217 exclusion phecode
712 Infective connective tissue disorders Musculoskeletal 1.02 0.703 – 1.48 0.916 26 304 exclusion phecode
713
Arthropathy associated with other disorders
Arthropathy associated with other disorders classified elsewhere
 Musculoskeletal 0.969 0.726 – 1.29 0.832 53 560 exclusion phecode
713.5
Arthropathy associated with neurological
Arthropathy associated with neurological disorders
 Musculoskeletal 0.987 0.616 – 1.58 0.958 19 231 exclusion phecode
714
Rheumatoid arthritis and other inflammatory
Rheumatoid arthritis and other inflammatory polyarthropathies
 Musculoskeletal 1.09 1.03 – 1.15 0.00258 1625 19767 exclusion phecode
714.1 Rheumatoid arthritis Musculoskeletal 1.1 1.04 – 1.16 0.00154 1473 17976 exclusion phecode
715 Other inflammatory spondylopathies Musculoskeletal 0.997 0.91 – 1.09 0.952 545 6510 exclusion phecode
715.1 Sacroiliitis NEC Musculoskeletal 1.05 0.787 – 1.39 0.759 53 472 exclusion phecode
715.2 Ankylosing spondylitis Musculoskeletal 0.958 0.817 – 1.12 0.598 182 2337 exclusion phecode
716 Other arthropathies Musculoskeletal 1.09 1.07 – 1.11 2.83e-19 13471 104203 exclusion phecode
716.1 Unspecified polyarthropathy or polyarthritis Musculoskeletal 1.15 1.08 – 1.22 8.07e-06 1280 13847 exclusion phecode
716.2 Unspecified monoarthritis Musculoskeletal 1.11 1.07 – 1.14 5.59e-12 5767 59651 exclusion phecode
716.9 Arthropathy NOS Musculoskeletal 1.09 1.07 – 1.12 1.09e-19 12913 102877 exclusion phecode
717 Polymyalgia Rheumatica Musculoskeletal 1.09 0.982 – 1.21 0.107 413 4392 exclusion phecode
720 Spinal stenosis Musculoskeletal 1.09 1.02 – 1.16 0.00698 1202 14119 exclusion phecode
721 Spondylosis and allied disorders Musculoskeletal 1.1 1.06 – 1.15 2.78e-06 2752 30772 exclusion phecode
721.1 Spondylosis without myelopathy Musculoskeletal 1.1 1.04 – 1.15 0.000532 1745 19836 exclusion phecode
721.2 Spondylosis with myelopathy Musculoskeletal 0.999 0.757 – 1.32 0.994 54 736 exclusion phecode
721.8 Other allied disorders of spine Musculoskeletal 1.16 0.958 – 1.4 0.129 132 1342 exclusion phecode
722 Intervertebral disc disorders Musculoskeletal 1.12 1.07 – 1.16 2.77e-08 3159 35831 exclusion phecode
722.1 Displacement of intervertebral disc Musculoskeletal 1.24 1.06 – 1.46 0.00838 173 2021 exclusion phecode
722.6 Degeneration of intervertebral disc Musculoskeletal 1.2 1.12 – 1.29 1.95e-07 1000 11396 exclusion phecode
722.8 Postlaminectomy syndrome Musculoskeletal 1.04 0.644 – 1.68 0.872 17 288 exclusion phecode
722.9 Other and unspecified disc disorder Musculoskeletal 1.08 1.02 – 1.14 0.00482 1553 17536 exclusion phecode
723 Other disorders of cervical region Musculoskeletal 0.957 0.81 – 1.13 0.607 161 2044 exclusion phecode
723.1 Torticollis Musculoskeletal 0.894 0.652 – 1.23 0.488 44 472 exclusion phecode
724 Other and unspecified disorders of back Musculoskeletal 1.07 0.988 – 1.16 0.0941 727 7997 exclusion phecode
724.1 Disorders of sacrum Musculoskeletal 1.06 0.882 – 1.26 0.553 145 1713 exclusion phecode
724.2 Disorders of coccyx Musculoskeletal 1.04 0.866 – 1.24 0.702 148 1728 exclusion phecode
724.8 Other symptoms referable to back Musculoskeletal 1.8 1.07 – 3.02 0.0274 18 240 exclusion phecode
724.9 Other unspecified back disorders Musculoskeletal 1.06 0.97 – 1.16 0.197 574 6160 exclusion phecode
726 Peripheral enthesopathies and allied syndromes Musculoskeletal 1.07 1.04 – 1.11 1.52e-06 5434 57467 exclusion phecode
726.1 Enthesopathy Musculoskeletal 1.06 1.02 – 1.1 0.00146 3603 37547 exclusion phecode
726.2 Synoviopathy Musculoskeletal 1.12 0.921 – 1.37 0.252 123 1349 exclusion phecode
726.3 Bursitis Musculoskeletal 1.09 0.962 – 1.22 0.185 314 3090 exclusion phecode
727 Other disorders of synovium, tendon, and bursa Musculoskeletal 1.1 1.06 – 1.15 4.72e-06 2775 29333 exclusion phecode
727.1 Synovitis and tenosynovitis Musculoskeletal 1.09 1.02 – 1.17 0.00991 1031 10956 exclusion phecode
727.2 Bursitis disorders Musculoskeletal 1.12 0.781 – 1.61 0.535 35 390 exclusion phecode
727.4 Ganglion and cyst of synovium, tendon, and bursa Musculoskeletal 1.16 1.09 – 1.24 4.01e-06 1205 12612 exclusion phecode
727.5 Rupture of synovium Musculoskeletal 0.999 0.86 – 1.16 0.986 205 2262 exclusion phecode
727.6 Rupture of tendon, nontraumatic Musculoskeletal 1.08 0.9 – 1.31 0.393 137 1345 exclusion phecode
727.7 Contracture of tendon (sheath) Musculoskeletal 0.726 0.535 – 0.985 0.0394 48 524 exclusion phecode
728 Disorders of muscle, ligament, and fascia Musculoskeletal 0.972 0.913 – 1.04 0.379 1143 12648 exclusion phecode
728.2 Laxity of ligament or hypermobility syndrome Musculoskeletal 0.899 0.758 – 1.06 0.216 159 1690 exclusion phecode
728.7 Fasciitis Musculoskeletal 0.986 0.927 – 1.05 0.651 1208 13193 exclusion phecode
728.71
Contracture of palmar fascia [Dupuytren's
Contracture of palmar fascia [Dupuytren's disease]
 Musculoskeletal 0.969 0.908 – 1.03 0.336 1068 11886 exclusion phecode
729 Other disorders of soft tissues Musculoskeletal 1.09 1.05 – 1.15 0.000108 2239 23837 exclusion phecode
729.1 Rheumatism, unspecified and fibrositis Musculoskeletal 1.08 0.967 – 1.21 0.169 389 4240 exclusion phecode
729.3 Panniculitis Musculoskeletal 0.941 0.67 – 1.32 0.727 37 423 exclusion phecode
731
Osteitis deformans and osteopathies associated
Osteitis deformans and osteopathies associated with other disorders classified elsewhere
 Musculoskeletal 1.16 0.954 – 1.41 0.135 126 1116 exclusion phecode
731.1 Osteitis deformans [Paget's disease of bone] Musculoskeletal 1.2 0.98 – 1.46 0.0786 121 1076 exclusion phecode
732 Osteochondropathies Musculoskeletal 0.945 0.8 – 1.12 0.511 176 1853 exclusion phecode
732.1 Juvenile osteochondrosis Musculoskeletal 1.03 0.805 – 1.32 0.81 78 826 exclusion phecode
732.7 Osteochondritis dissecans Musculoskeletal 0.853 0.551 – 1.32 0.477 27 219 exclusion phecode
733 Other disorders of bone and cartilage Musculoskeletal 1.1 1.01 – 1.2 0.0255 669 7299 exclusion phecode
733.2 Cyst of bone Musculoskeletal 1.02 0.835 – 1.25 0.831 118 1300 exclusion phecode
733.4 Aseptic necrosis of bone Musculoskeletal 1.17 0.994 – 1.37 0.0594 187 2143 exclusion phecode
733.6 Costochondritis Musculoskeletal 0.966 0.714 – 1.31 0.824 46 517 exclusion phecode
733.8 Malunion and nonunion of fracture Musculoskeletal 1.12 1.01 – 1.24 0.034 430 4857 exclusion phecode
733.9 Chondromalacia Musculoskeletal 1.07 0.769 – 1.48 0.702 43 498 exclusion phecode
735 Acquired foot deformities Musculoskeletal 1.08 1.04 – 1.12 3.61e-05 3933 39935 exclusion phecode
735.1 Flat foot Musculoskeletal 1.22 0.921 – 1.62 0.164 61 765 exclusion phecode
735.2 Acquired toe deformities Musculoskeletal 1.07 1.02 – 1.12 0.00931 2042 20855 exclusion phecode
735.21 Hammer toe (acquired) Musculoskeletal 1.07 0.993 – 1.16 0.0747 796 8045 exclusion phecode
735.23 Hallux rigidus Musculoskeletal 1.06 0.972 – 1.16 0.182 643 6181 exclusion phecode
735.3 Hallux valgus (Bunion) Musculoskeletal 1.1 1.05 – 1.14 2.05e-05 2803 28016 exclusion phecode
736 Other acquired deformities of limbs Musculoskeletal 1.03 0.937 – 1.12 0.585 569 6306 exclusion phecode
736.2 Acquired deformities of finger Musculoskeletal 0.954 0.768 – 1.18 0.671 88 934 exclusion phecode
737 Curvature of spine Musculoskeletal 1.03 0.928 – 1.15 0.563 417 4618 exclusion phecode
737.3 Kyphoscoliosis and scoliosis Musculoskeletal 0.994 0.889 – 1.11 0.91 388 4350 exclusion phecode
738 Other acquired musculoskeletal deformity Musculoskeletal 1.14 1.05 – 1.24 0.00258 653 7667 exclusion phecode
738.4 Acquired spondylolisthesis Musculoskeletal 1.17 1.06 – 1.29 0.00139 518 6111 exclusion phecode
739 Contracture of joint Musculoskeletal 1.01 0.857 – 1.2 0.876 173 1923 exclusion phecode
740 Osteoarthrosis Musculoskeletal 1.08 1.06 – 1.11 1.76e-12 10043 89432 exclusion phecode
740.1 Osteoarthritis; localized Musculoskeletal 1.07 1.04 – 1.1 6.79e-07 6479 65025 exclusion phecode
740.11 Osteoarthrosis, localized, primary Musculoskeletal 1.09 1.05 – 1.13 5.7e-06 3380 34356 exclusion phecode
740.12 Osteoarthrosis, localized, secondary Musculoskeletal 1.03 0.849 – 1.24 0.795 129 1337 exclusion phecode
740.2 Osteoarthrosis, generalized Musculoskeletal 1.11 0.957 – 1.28 0.169 231 2309 exclusion phecode
740.9 Osteoarthrosis NOS Musculoskeletal 1.11 1.07 – 1.15 1.08e-09 4279 48128 exclusion phecode
741 Symptoms and disorders of the joints Musculoskeletal 1.1 1.04 – 1.17 0.000818 1391 13747 exclusion phecode
741.1 Ankylosis of joint Musculoskeletal 0.949 0.66 – 1.37 0.779 35 389 exclusion phecode
741.2 Stiffness of joint Musculoskeletal 1.12 0.976 – 1.28 0.109 253 2466 exclusion phecode
741.3 Difficulty in walking Musculoskeletal 0.955 0.727 – 1.25 0.738 59 562 exclusion phecode
741.4 Joint effusions Musculoskeletal 1.06 0.968 – 1.16 0.202 560 5307 exclusion phecode
741.5 Hemarthrosis Musculoskeletal 0.907 0.634 – 1.3 0.591 35 417 exclusion phecode
741.6 Villonodular synovitis Musculoskeletal 0.971 0.607 – 1.55 0.901 20 233 exclusion phecode
742 Derangement of joint, non-traumatic Musculoskeletal 1.12 1.05 – 1.2 0.000485 1160 11432 exclusion phecode
742.1 Loose body in joint Musculoskeletal 1.15 0.945 – 1.41 0.162 123 1240 exclusion phecode
742.2
Pathological, developmental or recurrent
Pathological, developmental or recurrent dislocation
 Musculoskeletal 1.07 0.791 – 1.46 0.644 47 391 exclusion phecode
742.8 Articular cartilage disorder Musculoskeletal 1.2 1.03 – 1.39 0.0189 208 1981 exclusion phecode
742.9 Other derangement of joint Musculoskeletal 1.1 1.02 – 1.19 0.0133 815 8075 exclusion phecode
743
Osteoporosis, osteopenia and pathological
Osteoporosis, osteopenia and pathological fracture
 Musculoskeletal 1 0.963 – 1.04 0.879 2902 30691 exclusion phecode
743.1 Osteoporosis Musculoskeletal 0.996 0.953 – 1.04 0.854 2459 26114 exclusion phecode
743.11 Osteoporosis NOS Musculoskeletal 0.994 0.948 – 1.04 0.813 2180 22971 exclusion phecode
743.13 Other specified osteoporosis Musculoskeletal 1.01 0.855 – 1.19 0.922 167 1943 exclusion phecode
743.2 Pathologic fracture Musculoskeletal 1.12 0.941 – 1.33 0.204 156 1992 exclusion phecode
743.9
Osteopenia or other disorder of bone and
Osteopenia or other disorder of bone and cartilage
 Musculoskeletal 1.05 0.93 – 1.18 0.43 337 3251 exclusion phecode
745 Pain in joint Musculoskeletal 1.12 1.08 – 1.16 2.67e-08 3060 31484 exclusion phecode
747 Cardiac and circulatory congenital anomalies Congenital Anomalies 1.06 0.987 – 1.14 0.111 908 10328 exclusion phecode
747.1 Cardiac congenital anomalies Congenital Anomalies 1.05 0.973 – 1.13 0.217 842 9660 exclusion phecode
747.11 Cardiac shunt/ heart septal defect Congenital Anomalies 1.04 0.898 – 1.2 0.621 238 2325 exclusion phecode
747.12 Valvular heart disease/ heart chambers Congenital Anomalies 1 0.795 – 1.27 0.968 81 869 exclusion phecode
747.13 Congenital anomalies of great vessels Congenital Anomalies 1.03 0.939 – 1.13 0.52 522 6446 exclusion phecode
747.2
Congenital anomalies of peripheral vascular
Congenital anomalies of peripheral vascular system
 Congenital Anomalies 1.1 0.83 – 1.46 0.509 66 625 exclusion phecode
748 Anomalies of respiratory system, congenital Congenital Anomalies 1.3 0.815 – 2.06 0.273 22 177 exclusion phecode
749 Congenital anomalies of face and neck Congenital Anomalies 0.944 0.773 – 1.15 0.573 110 1216 exclusion phecode
750 Digestive congenital anomalies Congenital Anomalies 1 0.875 – 1.15 0.95 254 2545 exclusion phecode
750.1 Upper gastrointestinal congenital anomalies Congenital Anomalies 1.02 0.83 – 1.25 0.867 114 1179 exclusion phecode
750.13 Congenital anomalies of mouth/tongue Congenital Anomalies 1.07 0.831 – 1.38 0.589 70 673 exclusion phecode
750.2 Lower gastrointestinal congenital anomalies Congenital Anomalies 0.978 0.815 – 1.17 0.809 139 1384 exclusion phecode
750.21 Congenital anomalies of intestine Congenital Anomalies 0.993 0.786 – 1.26 0.953 83 871 exclusion phecode
750.22
Congenital anomaly of gallbladder, bile ducts
Congenital anomaly of gallbladder, bile ducts, liver, pancreas
 Congenital Anomalies 0.966 0.712 – 1.31 0.825 54 465 exclusion phecode
751 Genitourinary congenital anomalies Congenital Anomalies 1.06 0.971 – 1.16 0.187 587 6051 exclusion phecode
751.1 Congenital anomalies of genital organs Congenital Anomalies 1.06 0.936 – 1.2 0.352 289 2881 exclusion phecode
751.11 Congenital anomalies of female genital organs Congenital Anomalies 1.08 0.928 – 1.25 0.325 215 2025 exclusion phecode
751.12 Congenital anomalies of male genital organs Congenital Anomalies 1.06 0.815 – 1.37 0.682 62 741 exclusion phecode
751.2 Congenital anomalies of urinary system Congenital Anomalies 1.06 0.933 – 1.2 0.373 302 3186 exclusion phecode
751.21 Cystic kidney disease Congenital Anomalies 1.12 0.94 – 1.34 0.2 153 1605 exclusion phecode
751.22 Other specified congenital anomalies of kidney Congenital Anomalies 1.03 0.835 – 1.27 0.79 115 1281 exclusion phecode
752 Nervous system congenital anomalies Congenital Anomalies 1.07 0.892 – 1.28 0.464 141 1361 exclusion phecode
752.1 Neural tube defects Congenital Anomalies 1.07 0.871 – 1.32 0.512 110 1063 exclusion phecode
752.11 Spina bifida Congenital Anomalies 1.21 0.957 – 1.52 0.111 86 873 exclusion phecode
752.2
Other specified congenital anomalies of nervous
Other specified congenital anomalies of nervous system
 Congenital Anomalies 0.903 0.618 – 1.32 0.596 33 326 exclusion phecode
753 Congenital anomalies of the eye Congenital Anomalies 1.17 0.87 – 1.57 0.302 54 511 exclusion phecode
753.1 Congenital cataract and lens anomalies Congenital Anomalies 1.17 0.803 – 1.69 0.42 33 309 exclusion phecode
754 Congenital musculoskeletal deformities of spine Congenital Anomalies 1.16 0.853 – 1.59 0.339 47 459 exclusion phecode
755 Congenital anomalies of limbs Congenital Anomalies 1.03 0.87 – 1.21 0.759 173 1730 exclusion phecode
755.1 Congenital deformities of feet Congenital Anomalies 0.948 0.741 – 1.21 0.668 77 838 exclusion phecode
755.6
Other congenital anomalies of lower limb
Other congenital anomalies of lower limb, including pelvic girdle
 Congenital Anomalies 0.991 0.756 – 1.3 0.949 69 687 exclusion phecode
755.61 Congenital hip dysplasia and deformity Congenital Anomalies 1 0.717 – 1.4 0.994 46 469 exclusion phecode
756 Other congenital musculoskeletal anomalies Congenital Anomalies 1.2 1.03 – 1.4 0.0166 211 2416 exclusion phecode
756.3
Congenital anomalies of muscle, tendon, fascia
Congenital anomalies of muscle, tendon, fascia, and connective tissue
 Congenital Anomalies 1.29 0.894 – 1.87 0.172 33 339 exclusion phecode
756.5 Congenital osteodystrophies Congenital Anomalies 1.34 1.12 – 1.62 0.00172 146 1804 exclusion phecode
758 Chromosomal anomalies and genetic disorders Congenital Anomalies 1.17 0.888 – 1.55 0.259 58 672 exclusion phecode
758.1 Chromosomal anomalies Congenital Anomalies 1.7 1.09 – 2.64 0.0194 23 353 exclusion phecode
759 Other and unspecified congenital anomalies Congenital Anomalies 0.864 0.677 – 1.1 0.238 81 871 exclusion phecode
759.1 Anomalies of endocrine glands, congenital Congenital Anomalies 0.86 0.572 – 1.29 0.468 29 372 exclusion phecode
760 Back pain Symptoms 1.11 1.07 – 1.15 6.07e-09 3906 44171 exclusion phecode
761 Cervicalgia Symptoms 1.11 1.02 – 1.21 0.0188 654 7129 exclusion phecode
764 Sciatica Symptoms 1.14 1.05 – 1.23 0.00122 788 9411 exclusion phecode
766 Neuralgia, neuritis, and radiculitis NOS Symptoms 1.08 0.974 – 1.21 0.139 413 4651 exclusion phecode
770 Myalgia and myositis unspecified Symptoms 1.05 0.924 – 1.2 0.433 259 2489 exclusion phecode
771 Musculoskeletal symptoms referable to limbs Symptoms 1.18 1.05 – 1.33 0.00575 334 3411 exclusion phecode
771.1 Swelling of limb Symptoms 1.09 1.04 – 1.15 0.000776 1697 17920 exclusion phecode
772 Symptoms of the muscles Symptoms 1.02 0.889 – 1.18 0.757 240 2451 exclusion phecode
773 Pain in limb Symptoms 1.11 1.06 – 1.16 1.26e-05 2318 24753 exclusion phecode
780 Hypothermia/Chills Symptoms 0.95 0.713 – 1.26 0.723 57 612 exclusion phecode
781
Symptoms involving nervous and musculoskeletal
Symptoms involving nervous and musculoskeletal systems
 Symptoms 1.09 1.01 – 1.19 0.0378 655 7342 exclusion phecode
782.3 Edema Symptoms 1.09 0.992 – 1.19 0.073 555 6168 exclusion phecode
782.6 Pallor and flushing Symptoms 1.14 0.83 – 1.57 0.414 49 668 exclusion phecode
783 Fever of unknown origin Symptoms 0.961 0.908 – 1.02 0.169 1474 14920 exclusion phecode
785 Abdominal pain Symptoms 1.06 1.04 – 1.08 1.93e-11 15218 119213 exclusion phecode
788 Syncope and collapse Symptoms 1.06 1.02 – 1.1 0.00272 3392 33887 exclusion phecode
789 Nausea and vomiting Symptoms 1.05 1.01 – 1.08 0.00478 4367 46345 exclusion phecode
790 Nonspecific findings on examination of blood Symptoms 0.612 0.456 – 0.823 0.00113 51 560 exclusion phecode
790.1 Elevated sedimentation rate Symptoms 0.941 0.648 – 1.37 0.748 30 297 exclusion phecode
790.6 Other abnormal blood chemistry Symptoms 1.05 1 – 1.1 0.0375 2172 21736 exclusion phecode
791 Gangrene Symptoms 0.932 0.792 – 1.1 0.392 182 2012 exclusion phecode
792
Abnormal Papanicolaou smear of cervix and
Abnormal Papanicolaou smear of cervix and cervical HPV
 Symptoms 0.999 0.668 – 1.49 0.996 24 388 exclusion phecode
793
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of musculoskeletal system
 Symptoms 1.24 0.894 – 1.72 0.197 38 505 exclusion phecode
793.2
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of other intrathoracic organs (echocardiogram, etc)
 Symptoms 1.1 0.939 – 1.29 0.237 192 2109 exclusion phecode
794
Abnormal results of other function studies
Abnormal results of other function studies (bladder, pancreas, placenta, spleen, etc)
 Symptoms 0.86 0.64 – 1.16 0.319 50 531 exclusion phecode
797 Shock Symptoms 1.04 0.78 – 1.37 0.81 55 533 exclusion phecode
797.1 Cardiogenic shock Symptoms 1.14 0.814 – 1.58 0.456 38 346 exclusion phecode
798 Malaise and fatigue Symptoms 1 0.943 – 1.06 0.94 1293 13469 exclusion phecode
798.1 Chronic fatigue syndrome Symptoms 0.937 0.814 – 1.08 0.366 247 2477 exclusion phecode
800 Fracture of lower limb Injuries & Poisonings 1.04 0.992 – 1.08 0.116 2553 28012 exclusion phecode
800.1 Fracture of neck of femur Injuries & Poisonings 1.04 0.95 – 1.13 0.429 636 7147 exclusion phecode
800.2 Fracture of unspecified part of femur Injuries & Poisonings 1.03 0.777 – 1.36 0.851 58 667 exclusion phecode
800.3 Fracture of tibia and fibula Injuries & Poisonings 1.06 0.977 – 1.14 0.169 776 8454 exclusion phecode
800.4 Fracture of patella Injuries & Poisonings 0.964 0.848 – 1.1 0.58 271 2943 exclusion phecode
801 Fracture of ankle and foot Injuries & Poisonings 1.08 0.999 – 1.17 0.0524 762 8691 exclusion phecode
801.1 Fracture of foot Injuries & Poisonings 1.01 0.927 – 1.1 0.829 645 7213 exclusion phecode
802 Fracture of pelvis Injuries & Poisonings 1.11 0.974 – 1.27 0.116 259 2686 exclusion phecode
803 Fracture of upper limb Injuries & Poisonings 1.01 0.97 – 1.05 0.697 3337 33262 exclusion phecode
803.1 Fracture of humerus Injuries & Poisonings 0.996 0.915 – 1.08 0.925 652 6847 exclusion phecode
803.2 Fracture of radius and ulna Injuries & Poisonings 0.997 0.951 – 1.04 0.892 2200 21366 exclusion phecode
803.3 Fracture of clavicle or scapula Injuries & Poisonings 1.09 0.992 – 1.19 0.0739 534 5628 exclusion phecode
804 Fracture of hand or wrist Injuries & Poisonings 1.08 1.02 – 1.15 0.00883 1294 13060 exclusion phecode
805
Fracture of vertebral column without mention of
Fracture of vertebral column without mention of spinal cord injury
 Injuries & Poisonings 1.05 0.951 – 1.15 0.349 482 4949 exclusion phecode
807 Fracture of ribs Injuries & Poisonings 1.28 1.12 – 1.46 0.000341 252 2909 exclusion phecode
809 Fracture of unspecified bones Injuries & Poisonings 0.999 0.907 – 1.1 0.976 502 4854 exclusion phecode
817 Concussion Injuries & Poisonings 1.26 1.01 – 1.56 0.0363 103 910 exclusion phecode
818 Intracranial hemorrhage (injury) Injuries & Poisonings 1.02 0.863 – 1.2 0.846 174 1792 exclusion phecode
819
Skull and face fracture and other intercranial
Skull and face fracture and other intercranial injury
 Injuries & Poisonings 1.05 0.984 – 1.12 0.136 1071 11468 exclusion phecode
823 Torus fracture Injuries & Poisonings 1.06 0.966 – 1.16 0.227 589 6511 exclusion phecode
830 Dislocation Injuries & Poisonings 1.11 1.03 – 1.2 0.00807 790 8174 exclusion phecode
835 Internal derangement of knee Injuries & Poisonings 1.05 1.02 – 1.08 0.00051 5816 58512 exclusion phecode
836 Traumatic arthropathy Injuries & Poisonings 1.08 0.93 – 1.26 0.3 185 2059 exclusion phecode
840 Sprains and strains Injuries & Poisonings 0.977 0.833 – 1.15 0.774 188 1820 exclusion phecode
850 Hemorrhage or hematoma complicating a procedure Injuries & Poisonings 1.03 0.979 – 1.08 0.262 1942 20246 exclusion phecode
851
Complications of transplants and reattached
Complications of transplants and reattached limbs
 Injuries & Poisonings 1.2 0.927 – 1.56 0.164 64 596 exclusion phecode
853 Complication of colostomy or enterostomy Injuries & Poisonings 1.07 0.907 – 1.26 0.418 165 1925 exclusion phecode
854
Complications of cardiac/vascular device
Complications of cardiac/vascular device, implant, and graft
 Injuries & Poisonings 1.17 1.06 – 1.28 0.00153 491 6457 exclusion phecode
857
Mechanical complication of unspecified
Mechanical complication of unspecified genitourinary device, implant, and graft
 Injuries & Poisonings 1.08 0.978 – 1.2 0.124 432 4683 exclusion phecode
858 Complication of internal orthopedic device Injuries & Poisonings 1.12 1.05 – 1.19 0.000439 1189 12339 exclusion phecode
859
Complication due to other implant and internal
Complication due to other implant and internal device
 Injuries & Poisonings 1.13 1.07 – 1.21 7.5e-05 1209 12868 exclusion phecode
860 Bone marrow or stem cell transplant Neoplasms 0.743 0.499 – 1.11 0.144 31 257 exclusion phecode
870 Open wounds of head; neck; and trunk Injuries & Poisonings 1.1 1.03 – 1.17 0.00293 1174 13118 exclusion phecode
870.1 Open wound or laceration of eye or eyelid Injuries & Poisonings 1.14 0.917 – 1.41 0.241 93 1078 exclusion phecode
870.2 Open wound of ear Injuries & Poisonings 1.13 0.886 – 1.44 0.324 74 730 exclusion phecode
870.3 Other open wound of head and face Injuries & Poisonings 1.11 1.04 – 1.19 0.00244 986 10830 exclusion phecode
870.4 Open wound of nose and sinus Injuries & Poisonings 1.02 0.798 – 1.31 0.854 74 817 exclusion phecode
870.6 Open wound of neck Injuries & Poisonings 1.27 0.814 – 1.98 0.293 20 252 exclusion phecode
871 Open wounds of extremities Injuries & Poisonings 1.08 1.02 – 1.14 0.0134 1327 15540 exclusion phecode
871.1 Open wound of hand except finger(s) Injuries & Poisonings 1.18 0.749 – 1.87 0.468 17 201 exclusion phecode
871.2 Open wound of finger(s) Injuries & Poisonings 1.09 0.721 – 1.63 0.693 28 303 exclusion phecode
871.3 Open wound of foot except toe(s) alone Injuries & Poisonings 1.19 0.887 – 1.6 0.245 52 662 exclusion phecode
872 Traumatic amputation Injuries & Poisonings 1.22 1.02 – 1.45 0.0304 146 1725 exclusion phecode
873 Broken tooth Injuries & Poisonings 1.01 0.816 – 1.24 0.955 94 909 exclusion phecode
874 Complication of amputation stump Injuries & Poisonings 1.6 1.17 – 2.19 0.00323 44 629 exclusion phecode
905
Late effects of musculoskeletal and connective
Late effects of musculoskeletal and connective tissue injuries
 Injuries & Poisonings 1.18 0.901 – 1.54 0.232 59 597 exclusion phecode
907 Injuries to the nervous system Injuries & Poisonings 1.09 0.986 – 1.21 0.0919 441 4971 exclusion phecode
915 Superficial injury without mention of infection Injuries & Poisonings 1.03 0.971 – 1.08 0.354 1515 16443 exclusion phecode
916 Contusion Injuries & Poisonings 1.11 1.02 – 1.22 0.021 544 5641 exclusion phecode
930 Allergic reaction to food Injuries & Poisonings 0.815 0.612 – 1.09 0.163 56 764 exclusion phecode
938 Dermatitis due to solar radiation Injuries & Poisonings 0.972 0.814 – 1.16 0.755 143 1383 exclusion phecode
938.2 Chronic dermatitis due to solar radiation Injuries & Poisonings 0.913 0.734 – 1.14 0.417 96 889 exclusion phecode
939
Atopic/contact dermatitis due to other or
Atopic/contact dermatitis due to other or unspecified
 Dermatologic 0.98 0.907 – 1.06 0.61 777 8217 exclusion phecode
941 Adverse reaction to serum or vaccine Injuries & Poisonings 0.806 0.619 – 1.05 0.111 67 889 exclusion phecode
942 Infusion and transfusion reaction Injuries & Poisonings 0.96 0.713 – 1.29 0.785 52 405 exclusion phecode
946 Anaphylactic shock NOS Injuries & Poisonings 1.05 0.883 – 1.24 0.608 160 2137 exclusion phecode
947 Urticaria Injuries & Poisonings 0.999 0.83 – 1.2 0.99 141 1445 exclusion phecode
949 Allergies, other Injuries & Poisonings 1.1 0.922 – 1.31 0.296 155 1617 exclusion phecode
952
Spinal cord injury without evidence of spinal
Spinal cord injury without evidence of spinal bone injury
 Injuries & Poisonings 1.12 0.94 – 1.33 0.207 154 1528 exclusion phecode
957 Injury to other and unspecified nerves Injuries & Poisonings 1.17 0.916 – 1.5 0.208 81 988 exclusion phecode
958
Certain early complications of trauma or
Certain early complications of trauma or procedure
 Injuries & Poisonings 1.03 0.883 – 1.21 0.677 176 1899 exclusion phecode
958.1 Postoperative shock Injuries & Poisonings 1.11 0.702 – 1.74 0.665 21 212 exclusion phecode
958.2 Traumatic and surgical subcutaneous emphysema Injuries & Poisonings 1.03 0.696 – 1.53 0.872 25 259 exclusion phecode
960 Poisoning by antibiotics Injuries & Poisonings 1.04 1.01 – 1.06 0.00783 6836 73675 exclusion phecode
960.2 Allergy/adverse effect of penicillin Injuries & Poisonings 1.04 1.01 – 1.07 0.0148 5921 64182 exclusion phecode
961 Poisoning by other anti-infectives Injuries & Poisonings 0.899 0.742 – 1.09 0.273 132 1720 exclusion phecode
961.1 Poisoning/allergy of sulfonamides Injuries & Poisonings 1 0.895 – 1.13 0.936 369 3752 exclusion phecode
962 Poisoning by hormones and synthetic substitutes Injuries & Poisonings 1.12 0.922 – 1.36 0.253 124 1441 exclusion phecode
962.3
Hormones and synthetic substitutes causing
Hormones and synthetic substitutes causing adverse effects in therapeutic use
 Injuries & Poisonings 1.17 0.959 – 1.43 0.12 117 1422 exclusion phecode
963 Poisoning by primarily systemic agents Injuries & Poisonings 1.13 0.872 – 1.45 0.364 74 980 exclusion phecode
964
Poisoning by agents primarily affecting blood
Poisoning by agents primarily affecting blood constituents
 Injuries & Poisonings 1.14 0.922 – 1.42 0.22 95 1108 exclusion phecode
964.1 Anticoagulants causing adverse effects Injuries & Poisonings 1.15 0.925 – 1.43 0.208 93 1084 exclusion phecode
965
Poisoning by analgesics, antipyretics, and
Poisoning by analgesics, antipyretics, and antirheumatics
 Injuries & Poisonings 1.07 1.02 – 1.12 0.005 2102 24800 exclusion phecode
965.1
Opiates and related narcotics causing adverse
Opiates and related narcotics causing adverse effects in therapeutic use
 Injuries & Poisonings 1.05 0.948 – 1.17 0.342 438 4788 exclusion phecode
965.2
Antirheumatics causing adverse effects in
Antirheumatics causing adverse effects in therapeutic use
 Injuries & Poisonings 0.974 0.811 – 1.17 0.78 136 2061 exclusion phecode
965.3
Salicylates causing adverse effects in
Salicylates causing adverse effects in therapeutic use
 Injuries & Poisonings 1.25 1.02 – 1.55 0.0355 95 1590 exclusion phecode
966
Poisoning by anticonvulsants and
Poisoning by anticonvulsants and anti-Parkinsonism drugs
 Injuries & Poisonings 1.15 0.976 – 1.36 0.0938 169 2120 exclusion phecode
967
Adverse effects of sedatives or other central
Adverse effects of sedatives or other central nervous system depressants and anesthetics
 Injuries & Poisonings 1.17 1.01 – 1.35 0.0388 224 2363 exclusion phecode
969 Poisoning by psychotropic agents Injuries & Poisonings 1.18 1.07 – 1.29 0.000516 535 8176 exclusion phecode
971
Poisoning by drugs primarily affecting the
Poisoning by drugs primarily affecting the autonomic nervous system
 Injuries & Poisonings 1.51 1.13 – 2.02 0.00506 56 735 exclusion phecode
972
Poisoning by agents primarily affecting the
Poisoning by agents primarily affecting the cardiovascular system
 Injuries & Poisonings 1.51 1.17 – 1.94 0.00128 73 1065 exclusion phecode
972.6 Antihypertensive agents causing adverse effects Injuries & Poisonings 1.7 1.09 – 2.66 0.0199 26 329 exclusion phecode
973
Poisoning by agents primarily affecting the
Poisoning by agents primarily affecting the gastrointestinal system
 Injuries & Poisonings 1.65 1.12 – 2.44 0.012 33 433 exclusion phecode
974
Poisoning by water, mineral, and uric acid
Poisoning by water, mineral, and uric acid metabolism drugs
 Injuries & Poisonings 1.33 0.873 – 2.04 0.183 25 372 exclusion phecode
975
Poisoning by agents primarily acting on the
Poisoning by agents primarily acting on the smooth and skeletal muscles and respiratory system
 Injuries & Poisonings 0.89 0.53 – 1.49 0.659 17 251 exclusion phecode
976
Poisoning by agents primarily affecting skin &
Poisoning by agents primarily affecting skin & mucous membrane, ophthalmological, otorhinolaryngological, & dental drugs
 Injuries & Poisonings 1.02 0.639 – 1.63 0.93 19 257 exclusion phecode
977 Personal history of allergy to medicinal agents Injuries & Poisonings 1.13 0.897 – 1.41 0.306 91 978 exclusion phecode
979 Adverse drug events and drug allergies Injuries & Poisonings 1.16 1 – 1.34 0.0464 214 2937 exclusion phecode
981
Toxic effect of (non-ethyl) alcohol and
Toxic effect of (non-ethyl) alcohol and petroleum and other solvents
 Injuries & Poisonings 1.26 0.93 – 1.71 0.136 52 839 exclusion phecode
986 Toxic effect of carbon monoxide Injuries & Poisonings 1.5 0.959 – 2.34 0.0757 22 252 exclusion phecode
987 Toxic effect of other gases, fumes, or vapors Injuries & Poisonings 1.22 0.788 – 1.88 0.377 22 407 exclusion phecode
988 Toxic effect of noxious substances eaten as food Injuries & Poisonings 0.79 0.554 – 1.13 0.195 38 457 exclusion phecode
989
Toxic effect of other substances, chiefly
Toxic effect of other substances, chiefly nonmedicinal as to source
 Injuries & Poisonings 1.1 0.735 – 1.66 0.633 25 337 exclusion phecode
990 Effects radiation NOS Injuries & Poisonings 0.982 0.916 – 1.05 0.601 974 11919 exclusion phecode
994 Sepsis and SIRS Injuries & Poisonings 1 0.938 – 1.07 0.931 1016 11360 exclusion phecode
994.2 Sepsis Injuries & Poisonings 1 0.938 – 1.07 0.931 1016 11360 exclusion phecode
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