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Scores Smoking initiation UK Biobank (UKB) PheWAS analysis

Smoking initiation — UK Biobank (UKB) PRS PheWAS

PRS model
PRS ID exprsweb-smoker-yes-smokinginitiation-prscs-ukb-20211120Legacy PRSCSPRS-CSLarge GWAS

Evaluation cohort: UK Biobank (UKB).

This page pairs the PheWAS plot with the full sortable table for the all-subject and exclusion scans.

Read the all-subject and exclusion scans separately. The combined view is only a browsing aid, and the selected-phecode panel below is only meaningful when the same phecode exists in both scans.

ExPRS exclusion definition

Exclusion cohort: individuals without Smoking initiation.

For this ExPRS, the exclusion sensitivity scan removes individuals with the exposure itself before rerunning the PheWAS. This is an exposure-based sensitivity analysis rather than a diagnosis-based exclusion.

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Signal overview

The plot gives a quick view of the currently visible associations. Click a point to pin its details, inspect that phecode across scans when both rows exist, or open the matching phecode detail page.

776 rows visible 17 categories
Phecode Description Category OR 95% CI P value Cases Controls Analysis Link
008 Intestinal infection Infectious Diseases 1.12 1.1 – 1.15 1.13e-25 8842 88430 all phecode
008.5 Bacterial enteritis Infectious Diseases 1.19 1.14 – 1.23 2.42e-17 2718 27172 all phecode
008.52 Intestinal infection due to C. difficile Infectious Diseases 1.15 1.06 – 1.25 0.00053 653 6533 all phecode
008.6 Viral Enteritis Infectious Diseases 1.06 0.985 – 1.13 0.121 862 8622 all phecode
008.7 Intestinal infection due to protozoa Infectious Diseases 0.959 0.734 – 1.25 0.759 55 550 all phecode
010 Tuberculosis Infectious Diseases 1.11 0.95 – 1.3 0.184 166 1659 all phecode
038 Septicemia Infectious Diseases 1.06 1.03 – 1.09 0.000345 4175 41776 all phecode
038.1 Gram negative septicemia Infectious Diseases 1.09 1.01 – 1.17 0.0206 850 8501 all phecode
038.2 Gram positive septicemia Infectious Diseases 1.08 0.984 – 1.18 0.106 494 4978 all phecode
041 Bacterial infection NOS Infectious Diseases 1.14 1.12 – 1.16 1.85e-42 12017 120377 all phecode
041.1 Staphylococcus infections Infectious Diseases 1.12 1.08 – 1.16 1.2e-09 3128 31348 all phecode
041.2 Streptococcus infection Infectious Diseases 1.12 1.07 – 1.18 1.14e-05 1641 16433 all phecode
041.4 E. coli Infectious Diseases 1.15 1.11 – 1.2 3.28e-12 2730 27319 all phecode
053 Herpes zoster Infectious Diseases 1.11 1 – 1.23 0.0479 411 4137 all phecode
053.1 Herpes zoster with nervous system complications Infectious Diseases 1.11 0.898 – 1.38 0.328 95 949 all phecode
054 Herpes simplex Infectious Diseases 1.2 1.04 – 1.38 0.013 211 2107 all phecode
070 Viral hepatitis Infectious Diseases 1.28 1.18 – 1.39 1.07e-08 590 5916 all phecode
070.1 Viral hepatitis A Infectious Diseases 0.912 0.713 – 1.17 0.467 69 690 all phecode
070.2 Viral hepatitis B Infectious Diseases 1.27 1.06 – 1.51 0.00817 132 1330 all phecode
070.3 Viral hepatitis C Infectious Diseases 1.56 1.37 – 1.78 4.56e-11 255 2568 all phecode
070.4 Chronic hepatitis Infectious Diseases 1.07 0.942 – 1.21 0.304 276 2767 all phecode
070.9 Hepatitis NOS Infectious Diseases 1.19 1.08 – 1.32 0.000517 428 4287 all phecode
071 Human immunodeficiency virus [HIV] disease Infectious Diseases 1.25 1.06 – 1.48 0.00743 147 1467 all phecode
071.1 HIV infection, symptomatic Infectious Diseases 1.26 1.05 – 1.52 0.0135 117 1168 all phecode
078 Viral warts & HPV Infectious Diseases 1.05 0.984 – 1.12 0.139 1004 10036 all phecode
079 Viral infection Infectious Diseases 1.07 1.03 – 1.11 0.00117 2769 27694 all phecode
079.1 Varicella infection Infectious Diseases 1.01 0.781 – 1.3 0.949 64 640 all phecode
080 Postoperative infection Infectious Diseases 1.14 1.1 – 1.17 5.34e-16 4473 44775 all phecode
081
Infection/inflammation of internal prosthetic
Infection/inflammation of internal prosthetic device; implant; and graft
 Infectious Diseases 1.16 1.12 – 1.21 1.02e-12 2477 24765 all phecode
090
Sexually transmitted infections (not HIV or
Sexually transmitted infections (not HIV or hepatitis)
 Infectious Diseases 1.21 0.954 – 1.53 0.117 71 709 all phecode
1000 Burns Injuries & Poisonings 1.09 1 – 1.19 0.0394 578 5796 all phecode
1001 Foreign body injury Injuries & Poisonings 1.03 0.967 – 1.09 0.393 1199 12007 all phecode
1002
Symptoms concerning nutrition, metabolism, and
Symptoms concerning nutrition, metabolism, and development
 Injuries & Poisonings 1.09 1.06 – 1.12 9.78e-10 5480 54819 all phecode
1004
Other signs and symptoms involving emotional
Other signs and symptoms involving emotional state
 Injuries & Poisonings 1.29 1.15 – 1.45 2.44e-05 300 2997 all phecode
1005 Other symptoms Injuries & Poisonings 1.18 1.11 – 1.24 4.55e-09 1444 14422 all phecode
1006 Crushing injury Injuries & Poisonings 1.16 1.02 – 1.32 0.0259 256 2558 all phecode
1007 Injury to blood vessels Injuries & Poisonings 1.17 1.02 – 1.33 0.0197 256 2559 all phecode
1008 Crushing or internal injury to organs Injuries & Poisonings 1.16 1.09 – 1.23 6.44e-06 1013 10132 all phecode
1009 Injury, NOS Injuries & Poisonings 1.09 1.06 – 1.11 8.34e-14 8482 84911 all phecode
1010 Other tests Injuries & Poisonings 1.08 1.05 – 1.11 1.59e-08 5945 59512 all phecode
1011 Complications of surgical and medical procedures Injuries & Poisonings 1.13 1.1 – 1.15 5.23e-28 9152 91588 all phecode
1012 Late effect Injuries & Poisonings 0.944 0.77 – 1.16 0.582 105 1057 all phecode
1013 Asphyxia and hypoxemia Injuries & Poisonings 1.13 1 – 1.27 0.0428 316 3168 all phecode
1014 Effects of heat, cold and air pressure Injuries & Poisonings 0.967 0.751 – 1.24 0.793 66 659 all phecode
1015 Effects of other external causes Injuries & Poisonings 1.15 1.11 – 1.18 2.04e-17 4226 42294 all phecode
1019
Other ill-defined and unknown causes of
Other ill-defined and unknown causes of morbidity and mortality
 Injuries & Poisonings 1.1 1.08 – 1.11 4.51e-28 15895 159019 all phecode
110 Dermatophytosis / Dermatomycosis Infectious Diseases 1.07 0.945 – 1.21 0.295 279 2810 all phecode
110.1 Dermatophytosis Infectious Diseases 1.05 0.931 – 1.19 0.414 273 2750 all phecode
110.11 Dermatophytosis of nail Infectious Diseases 1.02 0.813 – 1.28 0.855 74 756 all phecode
110.12 Althete's foot Infectious Diseases 1.21 1.02 – 1.44 0.0265 141 1410 all phecode
112 Candidiasis Infectious Diseases 1.18 1.13 – 1.24 1.08e-13 2126 21275 all phecode
117 Mycoses Infectious Diseases 1.11 0.977 – 1.26 0.11 272 2719 all phecode
117.4 Aspergillosis Infectious Diseases 1.06 0.902 – 1.24 0.485 165 1650 all phecode
130 Spirochetal infection Infectious Diseases 0.93 0.738 – 1.17 0.54 80 800 all phecode
133 Arthropod-borne diseases Infectious Diseases 1.16 0.913 – 1.46 0.227 69 689 all phecode
134 Helminthiases Infectious Diseases 1.15 0.96 – 1.38 0.129 127 1267 all phecode
134.1 Intestinal helminthiases Infectious Diseases 1.16 0.954 – 1.41 0.139 106 1058 all phecode
136 Other infectious and parasitic diseases Infectious Diseases 0.935 0.815 – 1.07 0.343 205 2050 all phecode
145 Cancer of mouth Neoplasms 1.13 1.05 – 1.23 0.00236 642 6415 all phecode
145.2 Cancer of tongue Neoplasms 1.18 1.05 – 1.33 0.00459 310 3096 all phecode
145.3 Cancer of major salivary glands Neoplasms 1.04 0.848 – 1.26 0.734 105 1049 all phecode
145.5 Cancer of the mouth floor Neoplasms 1.21 0.922 – 1.6 0.166 54 539 all phecode
149 Cancer of larynx, pharynx, nasal cavities Neoplasms 1.23 1.13 – 1.33 6.87e-07 635 6342 all phecode
149.1 Cancer of oropharynx Neoplasms 1.18 1.03 – 1.34 0.014 252 2517 all phecode
149.4 Cancer of larynx Neoplasms 1.4 1.23 – 1.58 1.24e-07 265 2640 all phecode
149.9 Cancer of of nasal cavities Neoplasms 1.03 0.793 – 1.34 0.816 57 570 all phecode
150 Cancer of esophagus Neoplasms 1.16 1.07 – 1.24 0.000115 762 7630 all phecode
151 Cancer of stomach Neoplasms 1.12 1.03 – 1.22 0.0111 569 5696 all phecode
153 Colorectal cancer Neoplasms 1.03 1 – 1.06 0.0517 4580 45799 all phecode
153.2 Colon cancer Neoplasms 1.02 0.983 – 1.06 0.284 3105 31046 all phecode
153.3
Malignant neoplasm of rectum, rectosigmoid
Malignant neoplasm of rectum, rectosigmoid junction, and anus
 Neoplasms 1.04 0.99 – 1.08 0.125 2164 21640 all phecode
155 Cancer of liver and intrahepatic bile duct Neoplasms 1.17 1.05 – 1.29 0.0031 400 4008 all phecode
155.1 Malignant neoplasm of liver, primary Neoplasms 1.27 1.08 – 1.51 0.00442 158 1580 all phecode
157 Pancreatic cancer Neoplasms 1.1 1.01 – 1.19 0.025 659 6582 all phecode
158
Neoplasm of unspecified nature of digestive
Neoplasm of unspecified nature of digestive system
 Neoplasms 1.03 0.971 – 1.1 0.301 1063 10635 all phecode
159
Malignant neoplasm of other and ill-defined
Malignant neoplasm of other and ill-defined sites within the digestive organs and peritoneum
 Neoplasms 1.07 1.04 – 1.1 3.23e-06 5567 55694 all phecode
159.2
Malignant neoplasm of small intestine
Malignant neoplasm of small intestine, including duodenum
 Neoplasms 1.14 0.981 – 1.33 0.0875 190 1900 all phecode
159.3
Malignant neoplasm of gallbladder and
Malignant neoplasm of gallbladder and extrahepatic bile ducts
 Neoplasms 1.1 0.949 – 1.27 0.208 205 2048 all phecode
159.4
Malignant neoplasm of retroperitoneum and
Malignant neoplasm of retroperitoneum and peritoneum
 Neoplasms 1.02 0.881 – 1.18 0.778 193 1925 all phecode
164 Cancer of intrathoracic organs Neoplasms 0.856 0.653 – 1.12 0.259 60 600 all phecode
165 Cancer within the respiratory system Neoplasms 1.32 1.27 – 1.37 7e-45 2824 28235 all phecode
165.1 Cancer of bronchus; lung Neoplasms 1.36 1.31 – 1.42 1.21e-43 2230 22307 all phecode
170 Cancer of bone and connective tissue Neoplasms 1 0.909 – 1.11 0.95 437 4364 all phecode
170.1 Bone cancer Neoplasms 1.02 0.849 – 1.22 0.837 131 1309 all phecode
170.2 Cancer of connective tissue Neoplasms 1.01 0.9 – 1.13 0.892 331 3303 all phecode
172 Skin cancer Neoplasms 0.994 0.976 – 1.01 0.477 13495 134987 all phecode
172.1 Melanomas of skin, dx or hx Neoplasms 0.97 0.932 – 1.01 0.13 2681 26792 all phecode
172.11 Melanomas of skin Neoplasms 0.97 0.932 – 1.01 0.132 2713 27112 all phecode
172.2 Other non-epithelial cancer of skin Neoplasms 0.997 0.977 – 1.02 0.745 11000 110056 all phecode
172.3 Carcinoma in situ of skin Neoplasms 1.07 0.985 – 1.15 0.113 666 6656 all phecode
173 Neoplasm of uncertain behavior of skin Neoplasms 0.861 0.738 – 1 0.0564 181 1818 all phecode
174 Breast cancer Neoplasms 1.02 0.997 – 1.03 0.0921 12686 126597 all phecode
174.1 Breast cancer [female] Neoplasms 1.02 0.999 – 1.04 0.0694 12476 124506 all phecode
174.11 Malignant neoplasm of female breast Neoplasms 1.02 1 – 1.04 0.0401 11757 117502 all phecode
174.3 Neoplasm of uncertain behavior of breast Neoplasms 1.02 0.842 – 1.25 0.81 115 1148 all phecode
175 Acquired absence of breast Neoplasms 1.06 1.01 – 1.1 0.0123 2400 24010 all phecode
180 Cervical cancer and dysplasia Neoplasms 1.1 1.05 – 1.15 4.44e-05 2174 21747 all phecode
180.1 Cervical cancer Neoplasms 1.04 0.919 – 1.18 0.529 272 2720 all phecode
180.3
Cervical intraepithelial neoplasia [CIN]
Cervical intraepithelial neoplasia [CIN] [Cervical dysplasia]
 Neoplasms 1.1 1.05 – 1.15 3.97e-05 2078 20784 all phecode
182 Malignant neoplasm of uterus Neoplasms 0.96 0.906 – 1.02 0.169 1282 12836 all phecode
184 Cancer of other female genital organs Neoplasms 0.987 0.933 – 1.04 0.641 1378 13772 all phecode
184.1
Malignant neoplasm of ovary and other uterine
Malignant neoplasm of ovary and other uterine adnexa
 Neoplasms 0.948 0.886 – 1.01 0.116 967 9667 all phecode
184.11 Malignant neoplasm of ovary Neoplasms 0.942 0.88 – 1.01 0.0836 939 9387 all phecode
184.2
Cancer of other female genital organs
Cancer of other female genital organs (excluding uterus and ovary)
 Neoplasms 1.09 0.962 – 1.22 0.182 305 3049 all phecode
185 Cancer of prostate Neoplasms 0.995 0.969 – 1.02 0.7 5974 58812 all phecode
187 Cancer of other male genital organs Neoplasms 1.04 0.948 – 1.15 0.394 449 4485 all phecode
187.1
Malignant neoplasm of unspecified male genital
Malignant neoplasm of unspecified male genital organ
 Neoplasms 1.19 0.931 – 1.53 0.163 70 700 all phecode
187.2 Malignant neoplasm of testis Neoplasms 1.06 0.938 – 1.19 0.371 287 2868 all phecode
187.8
Neoplasm of uncertain behavior of male genital
Neoplasm of uncertain behavior of male genital organs
 Neoplasms 0.938 0.777 – 1.13 0.502 110 1098 all phecode
189
Cancer of urinary organs (incl. kidney and
Cancer of urinary organs (incl. kidney and bladder)
 Neoplasms 1.08 1.04 – 1.11 7.17e-06 4160 41604 all phecode
189.1 Cancer of kidney and renal pelvis Neoplasms 1.07 1 – 1.13 0.0479 1073 10723 all phecode
189.11 Malignant neoplasm of kidney, except pelvis Neoplasms 1.07 1.01 – 1.14 0.0301 1033 10324 all phecode
189.12 Malignant neoplasm of renal pelvis Neoplasms 0.977 0.756 – 1.26 0.856 66 660 all phecode
189.2 Cancer of bladder Neoplasms 1.08 1.03 – 1.12 0.000659 2409 24113 all phecode
189.21 Malignant neoplasm of bladder Neoplasms 1.1 1.05 – 1.15 4.81e-05 2142 21447 all phecode
189.4 Malignant neoplasm of other urinary organs Neoplasms 1.02 0.858 – 1.21 0.824 144 1439 all phecode
190 Cancer of eye Neoplasms 0.936 0.799 – 1.09 0.406 176 1758 all phecode
191
Manlignant and unknown neoplasms of brain and
Manlignant and unknown neoplasms of brain and nervous system
 Neoplasms 0.996 0.922 – 1.08 0.928 689 6879 all phecode
191.1 Cancer of brain and nervous system Neoplasms 0.996 0.914 – 1.09 0.932 566 5650 all phecode
191.11 Cancer of brain Neoplasms 1.01 0.925 – 1.1 0.807 525 5240 all phecode
193 Thyroid cancer Neoplasms 0.995 0.891 – 1.11 0.935 346 3466 all phecode
194 Cancer of other endocrine glands Neoplasms 0.976 0.797 – 1.2 0.814 95 949 all phecode
195 Cancer, suspected or other Neoplasms 1.06 1.04 – 1.08 4.22e-13 16967 165463 all phecode
195.1 Malignant neoplasm, other Neoplasms 1.06 1.04 – 1.08 1.09e-12 16267 159497 all phecode
197 Chemotherapy Neoplasms 1.09 1.08 – 1.11 4.63e-36 21433 213213 all phecode
198 Secondary malignant neoplasm Neoplasms 1.07 1.05 – 1.09 4.59e-10 9552 95503 all phecode
198.1 Secondary malignancy of lymph nodes Neoplasms 1.03 1 – 1.06 0.0379 5368 53670 all phecode
198.2 Secondary malignancy of respiratory organs Neoplasms 1.08 1.04 – 1.13 0.000268 2267 22670 all phecode
198.3
Secondary malignant neoplasm of digestive
Secondary malignant neoplasm of digestive systems
 Neoplasms 0.995 0.944 – 1.05 0.844 1549 15496 all phecode
198.4 Secondary malignant neoplasm of liver Neoplasms 1.11 1.06 – 1.15 8.92e-07 2665 26648 all phecode
198.5 Secondary malignancy of brain/spine Neoplasms 1.17 1.09 – 1.25 1.24e-05 848 8473 all phecode
198.6 Secondary malignancy of bone Neoplasms 1.13 1.08 – 1.18 4.12e-08 2161 21600 all phecode
198.7 Secondary malignant neoplasm of skin Neoplasms 1 0.865 – 1.16 0.962 188 1890 all phecode
199 Neoplasm of uncertain behavior Neoplasms 1.14 1.08 – 1.21 1.03e-06 1432 14313 all phecode
199.4 Neurofibromatosis Neoplasms 1.08 0.881 – 1.31 0.473 95 950 all phecode
200 Myeloproliferative disease Neoplasms 1.04 0.974 – 1.11 0.245 991 9911 all phecode
200.1 Polycythemia vera Neoplasms 1.07 0.959 – 1.18 0.237 387 3867 all phecode
201 Hodgkin's disease Neoplasms 0.985 0.868 – 1.12 0.82 259 2598 all phecode
202 Cancer of other lymphoid, histiocytic tissue Neoplasms 1 0.961 – 1.05 0.877 2264 22709 all phecode
202.2 Non-Hodgkins lymphoma Neoplasms 0.986 0.939 – 1.03 0.559 1802 18073 all phecode
202.21 Nodular lymphoma Neoplasms 0.954 0.855 – 1.06 0.391 363 3647 all phecode
202.24 Large cell lymphoma Neoplasms 0.963 0.885 – 1.05 0.389 581 5824 all phecode
204 Leukemia Neoplasms 1.03 0.977 – 1.08 0.295 1660 16630 all phecode
204.1 Lymphoid leukemia Neoplasms 1.03 0.944 – 1.12 0.513 577 5784 all phecode
204.11 Lymphoid leukemia, acute Neoplasms 0.951 0.717 – 1.26 0.729 56 560 all phecode
204.12 Lymphoid leukemia, chronic Neoplasms 1.03 0.935 – 1.13 0.585 507 5084 all phecode
204.2 Myeloid leukemia Neoplasms 0.954 0.867 – 1.05 0.341 462 4617 all phecode
204.21 Myeloid leukemia, acute Neoplasms 0.955 0.852 – 1.07 0.431 329 3287 all phecode
204.22 Myeloid leukemia, chronic Neoplasms 0.938 0.791 – 1.11 0.459 144 1440 all phecode
204.4 Multiple myeloma Neoplasms 1.04 0.95 – 1.13 0.412 555 5560 all phecode
208 Benign neoplasm of colon Neoplasms 1.1 1.09 – 1.12 1.62e-39 19856 191891 all phecode
210 Benign neoplasm of lip, oral cavity, and pharynx Neoplasms 1.08 1.01 – 1.15 0.0245 978 9781 all phecode
211
Benign neoplasm of other parts of digestive
Benign neoplasm of other parts of digestive system
 Neoplasms 1.01 0.984 – 1.04 0.404 5243 52452 all phecode
212
Benign neoplasm of respiratory and
Benign neoplasm of respiratory and intrathoracic organs
 Neoplasms 1.14 1.02 – 1.27 0.0173 347 3466 all phecode
213 Benign neoplasm of bone and articular cartilage Neoplasms 1.06 0.94 – 1.18 0.36 318 3187 all phecode
214 Lipoma Neoplasms 1.1 1.08 – 1.13 1.1e-13 6231 62346 all phecode
214.1 Lipoma of skin and subcutaneous tissue Neoplasms 1.12 1.09 – 1.16 3.98e-14 4585 45872 all phecode
215
Other benign neoplasm of connective and other
Other benign neoplasm of connective and other soft tissue
 Neoplasms 1.04 0.981 – 1.11 0.181 1107 11061 all phecode
216 Benign neoplasm of skin Neoplasms 0.996 0.973 – 1.02 0.756 7664 76660 all phecode
217 Vascular hamartomas and non-neoplastic nevi Neoplasms 1.09 1.01 – 1.19 0.03 632 6313 all phecode
217.1 Nevus, non-neoplastic Neoplasms 1.08 0.987 – 1.17 0.0954 595 5943 all phecode
218 Benign neoplasm of uterus Neoplasms 1.02 1 – 1.04 0.0416 10023 100200 all phecode
218.1 Uterine leiomyoma Neoplasms 1.02 0.998 – 1.04 0.0738 10241 102376 all phecode
218.2 Other benign neoplasm of uterus Neoplasms 1.07 0.962 – 1.19 0.207 355 3548 all phecode
220 Benign neoplasm of ovary Neoplasms 1.03 0.979 – 1.09 0.232 1445 14483 all phecode
221 Benign neoplasm of other female genital organs Neoplasms 1.08 0.94 – 1.23 0.285 220 2196 all phecode
222 Benign neoplasm of male genital organs Neoplasms 1.06 0.9 – 1.24 0.507 160 1600 all phecode
223
Benign neoplasm of kidney and other urinary
Benign neoplasm of kidney and other urinary organs
 Neoplasms 1.11 0.956 – 1.3 0.167 173 1729 all phecode
224 Benign neoplasm of eye Neoplasms 0.995 0.828 – 1.2 0.954 129 1299 all phecode
224.1 Benign neoplasm of eye, uveal Neoplasms 1.01 0.786 – 1.3 0.928 67 680 all phecode
225
Benign neoplasm of brain and other parts of
Benign neoplasm of brain and other parts of nervous system
 Neoplasms 0.95 0.883 – 1.02 0.17 816 8155 all phecode
225.1
Benign neoplasm of brain, cranial nerves
Benign neoplasm of brain, cranial nerves, meninges
 Neoplasms 0.938 0.87 – 1.01 0.0954 775 7756 all phecode
225.2 Benign neoplasm of spinal cord, meninges Neoplasms 1.1 0.845 – 1.42 0.489 59 589 all phecode
226 Benign neoplasm of thyroid glands Neoplasms 1.02 0.899 – 1.15 0.776 266 2664 all phecode
227
Benign neoplasm of other endocrine glands and
Benign neoplasm of other endocrine glands and related structures
 Neoplasms 1.07 0.999 – 1.15 0.0545 861 8635 all phecode
227.1 Benign neoplasm of adrenal gland Neoplasms 1.1 0.946 – 1.28 0.216 186 1857 all phecode
227.2 Benign neoplasm of parathyroid gland Neoplasms 1.06 0.949 – 1.17 0.318 371 3709 all phecode
227.3
Benign neoplasm of pituitary gland and
Benign neoplasm of pituitary gland and craniopharyngeal duct (pouch)
 Neoplasms 1.1 0.978 – 1.24 0.112 309 3114 all phecode
228 Hemangioma and lymphangioma, any site Neoplasms 0.984 0.935 – 1.04 0.548 1596 15966 all phecode
229 Benign neoplasm of unspecified sites Neoplasms 1.03 0.985 – 1.07 0.21 2397 23955 all phecode
240 Simple and unspecified goiter Endocrine/metabolic 1.08 0.993 – 1.17 0.0733 600 6016 all phecode
241 Nontoxic nodular goiter Endocrine/metabolic 1.02 0.959 – 1.08 0.528 1107 11092 all phecode
241.1 Nontoxic uninodular goiter Endocrine/metabolic 0.959 0.874 – 1.05 0.381 471 4706 all phecode
241.2 Nontoxic multinodular goiter Endocrine/metabolic 1.06 0.98 – 1.15 0.143 676 6784 all phecode
242 Thyrotoxicosis with or without goiter Endocrine/metabolic 1.02 0.976 – 1.08 0.325 1854 18531 all phecode
242.1 Graves' disease Endocrine/metabolic 0.997 0.905 – 1.1 0.954 456 4553 all phecode
242.2 Toxic multinodular goiter Endocrine/metabolic 1.16 0.934 – 1.45 0.176 91 910 all phecode
242.3 Exophthalmos Endocrine/metabolic 1.04 0.878 – 1.24 0.624 138 1379 all phecode
244 Hypothyroidism Endocrine/metabolic 1.09 1.07 – 1.11 1.36e-24 14590 145053 all phecode
244.1 Secondary hypothyroidism Endocrine/metabolic 1.07 1.01 – 1.14 0.0285 1108 11079 all phecode
244.2 Acquired hypothyroidism Endocrine/metabolic 1.27 1.03 – 1.56 0.0225 101 1010 all phecode
244.4 Hypothyroidism NOS Endocrine/metabolic 1.09 1.08 – 1.11 3.42e-24 13918 138926 all phecode
245 Thyroiditis Endocrine/metabolic 1.13 0.995 – 1.27 0.0592 288 2877 all phecode
245.2 Chronic thyroiditis Endocrine/metabolic 1.14 0.996 – 1.32 0.0562 218 2177 all phecode
245.21 Chronic lymphocytic thyroiditis Endocrine/metabolic 1.14 0.987 – 1.31 0.0748 210 2097 all phecode
246 Other disorders of thyroid Endocrine/metabolic 1.04 0.936 – 1.15 0.488 397 3975 all phecode
250 Diabetes mellitus Endocrine/metabolic 1.16 1.14 – 1.17 4.08e-83 19787 186006 all phecode
250.1 Type 1 diabetes Endocrine/metabolic 1.1 1.06 – 1.14 1.59e-06 2758 27621 all phecode
250.11 Type 1 diabetes with ketoacidosis Endocrine/metabolic 1.08 0.949 – 1.24 0.234 239 2389 all phecode
250.12 Type 1 diabetes with renal manifestations Endocrine/metabolic 1.02 0.814 – 1.29 0.836 76 770 all phecode
250.13 Type 1 diabetes with ophthalmic manifestations Endocrine/metabolic 1.01 0.915 – 1.11 0.897 473 4744 all phecode
250.14 Type 1 diabetes with neurological manifestations Endocrine/metabolic 1.1 0.933 – 1.29 0.264 160 1610 all phecode
250.2 Type 2 diabetes Endocrine/metabolic 1.17 1.15 – 1.19 1.68e-89 17831 170202 all phecode
250.21 Type 2 diabetes with ketoacidosis Endocrine/metabolic 1.12 0.913 – 1.36 0.286 104 1050 all phecode
250.22 Type 2 diabetes with renal manifestations Endocrine/metabolic 1.09 0.942 – 1.26 0.249 200 2018 all phecode
250.23 Type 2 diabetes with ophthalmic manifestations Endocrine/metabolic 1.18 1.11 – 1.27 4.98e-07 986 9907 all phecode
250.24 Type 2 diabetes with neurological manifestations Endocrine/metabolic 1.2 1.1 – 1.32 9.7e-05 503 5066 all phecode
250.4 Abnormal glucose Endocrine/metabolic 1.12 1.03 – 1.21 0.0049 680 6827 all phecode
250.41 Impaired fasting glucose Endocrine/metabolic 1.13 0.996 – 1.29 0.0582 265 2659 all phecode
250.42 Other abnormal glucose Endocrine/metabolic 1.13 1.02 – 1.25 0.0154 416 4178 all phecode
250.5 Glycosuria or Acetonuria Endocrine/metabolic 1.2 1 – 1.44 0.0485 131 1308 all phecode
250.6 Polyneuropathy in diabetes Endocrine/metabolic 1.21 1.09 – 1.35 0.000625 349 3495 all phecode
250.7 Diabetic retinopathy Endocrine/metabolic 1.1 1.04 – 1.16 0.000992 1329 13335 all phecode
251.1 Hypoglycemia Endocrine/metabolic 1.12 1.04 – 1.19 0.00128 932 9370 all phecode
252 Disorders of parathyroid gland Endocrine/metabolic 0.98 0.915 – 1.05 0.574 873 8719 all phecode
252.1 Hyperparathyroidism Endocrine/metabolic 0.988 0.918 – 1.06 0.742 781 7802 all phecode
252.2 Hypoparathyroidism Endocrine/metabolic 0.865 0.73 – 1.02 0.0907 142 1418 all phecode
253
Disorders of the pituitary gland and its
Disorders of the pituitary gland and its hypothalamic control
 Endocrine/metabolic 1.01 0.934 – 1.09 0.803 681 6821 all phecode
253.1 Pituitary hyperfunction Endocrine/metabolic 1.18 1.01 – 1.38 0.0351 187 1867 all phecode
253.11 Acromegaly and gigantism Endocrine/metabolic 1.05 0.851 – 1.3 0.639 95 949 all phecode
253.2 Pituitary hypofunction Endocrine/metabolic 0.945 0.832 – 1.07 0.386 260 2618 all phecode
253.3 Diabetes insipidus Endocrine/metabolic 0.971 0.782 – 1.21 0.792 92 919 all phecode
253.7 Other disorders of neurohypophysis Endocrine/metabolic 1.01 0.861 – 1.18 0.93 158 1578 all phecode
255 Disorders of adrenal glands Endocrine/metabolic 1.07 0.985 – 1.16 0.11 638 6374 all phecode
255.1 Adrenal hyperfunction Endocrine/metabolic 1.18 1.02 – 1.38 0.0292 180 1797 all phecode
255.11 Cushing's syndrome Endocrine/metabolic 1.2 0.981 – 1.47 0.0762 103 1029 all phecode
255.12 Hyperaldosteronism Endocrine/metabolic 1.02 0.811 – 1.28 0.864 76 759 all phecode
255.2 Adrenal hypofunction Endocrine/metabolic 1.02 0.921 – 1.14 0.656 362 3617 all phecode
255.21 Glucocorticoid deficiency Endocrine/metabolic 1.03 0.922 – 1.14 0.638 361 3607 all phecode
256 Ovarian dysfunction Endocrine/metabolic 1.02 0.891 – 1.17 0.774 240 2397 all phecode
256.4 Polycystic ovaries Endocrine/metabolic 1.01 0.879 – 1.17 0.842 209 2088 all phecode
257 Testicular dysfunction Endocrine/metabolic 0.972 0.826 – 1.14 0.736 160 1619 all phecode
257.1 Testicular hypofunction Endocrine/metabolic 0.98 0.83 – 1.16 0.817 152 1539 all phecode
258 Iatrogenic endocrine disorders Endocrine/metabolic 1.1 0.891 – 1.35 0.383 102 1020 all phecode
259 Other endocrine disorders Endocrine/metabolic 1.17 0.989 – 1.39 0.0666 149 1498 all phecode
260 Protein-calorie malnutrition Endocrine/metabolic 1.03 0.888 – 1.19 0.717 202 2018 all phecode
260.1 Cachexia Endocrine/metabolic 1.26 0.956 – 1.65 0.102 51 510 all phecode
260.6 Anorexia Endocrine/metabolic 1.06 0.991 – 1.14 0.0887 830 8317 all phecode
261 Vitamin deficiency Endocrine/metabolic 1.14 1.08 – 1.21 9.8e-06 1199 11974 all phecode
261.2 Vitamin B-complex deficiencies Endocrine/metabolic 1.19 1.1 – 1.28 7.52e-06 755 7541 all phecode
261.4 Vitamin D deficiency Endocrine/metabolic 1.04 0.941 – 1.15 0.446 447 4462 all phecode
261.41 Rickets or osteomalacia Endocrine/metabolic 1.05 0.836 – 1.33 0.661 77 769 all phecode
262 Mineral deficiency NEC Endocrine/metabolic 1.03 0.902 – 1.17 0.678 241 2407 all phecode
269 Proteinuria Endocrine/metabolic 1.14 1.02 – 1.27 0.0201 338 3378 all phecode
270
Disorders of protein plasma/amino-acid
Disorders of protein plasma/amino-acid transport and metabolism
 Endocrine/metabolic 1.18 1.05 – 1.33 0.00552 303 3028 all phecode
270.3 Disorders of plasma protein metabolism Endocrine/metabolic 1.18 1.04 – 1.34 0.0109 261 2608 all phecode
270.32 Paraproteinemia Endocrine/metabolic 1.2 1.03 – 1.4 0.0164 191 1910 all phecode
270.33 Amyloidosis Endocrine/metabolic 1.12 0.923 – 1.37 0.243 113 1129 all phecode
270.35 Macroglobulinemia Endocrine/metabolic 1.17 0.92 – 1.49 0.201 69 689 all phecode
271
Disorders of carbohydrate transport and
Disorders of carbohydrate transport and metabolism
 Endocrine/metabolic 0.954 0.812 – 1.12 0.569 160 1600 all phecode
271.3
Intestinal disaccharidase deficiencies and
Intestinal disaccharidase deficiencies and disaccharide malabsorption
 Endocrine/metabolic 0.92 0.773 – 1.09 0.348 139 1391 all phecode
272 Disorders of lipoid metabolism Endocrine/metabolic 1.13 1.12 – 1.14 3.87e-96 34835 235433 all phecode
272.1 Hyperlipidemia Endocrine/metabolic 1.13 1.12 – 1.14 2.39e-96 34764 235203 all phecode
272.11 Hypercholesterolemia Endocrine/metabolic 1.13 1.11 – 1.14 4.23e-89 32324 228083 all phecode
272.12 Hyperglyceridemia Endocrine/metabolic 1.17 0.897 – 1.52 0.249 58 580 all phecode
272.13 Mixed hyperlipidemia Endocrine/metabolic 1.07 0.91 – 1.26 0.412 164 1637 all phecode
272.9 Unspecified disorder of lipoid metabolism Endocrine/metabolic 1.04 0.901 – 1.19 0.614 211 2109 all phecode
274 Gout and other crystal arthropathies Endocrine/metabolic 1.16 1.12 – 1.2 2.45e-18 3724 37231 all phecode
274.1 Gout Endocrine/metabolic 1.16 1.12 – 1.21 3.15e-16 3171 31705 all phecode
274.11 Gouty arthropathy Endocrine/metabolic 1.07 0.882 – 1.29 0.505 112 1119 all phecode
274.2 Crystal arthropathies Endocrine/metabolic 1.15 1.06 – 1.25 0.000857 613 6124 all phecode
274.21 Chondrocalcinosis Endocrine/metabolic 1.19 1.09 – 1.3 8.68e-05 558 5576 all phecode
275 Disorders of mineral metabolism Endocrine/metabolic 1.12 1.07 – 1.17 1.13e-06 2107 21070 all phecode
275.1 Disorders of iron metabolism Hematopoietic 1.12 1.04 – 1.22 0.0052 653 6535 all phecode
275.3 Disorders of magnesium metabolism Endocrine/metabolic 1.19 1.07 – 1.33 0.00107 375 3745 all phecode
275.5 Disorders of calcium/phosphorus metabolism Endocrine/metabolic 1.11 1.04 – 1.17 0.000878 1202 12019 all phecode
275.53 Disorders of phosphorus metabolism Endocrine/metabolic 1.09 0.931 – 1.28 0.278 171 1717 all phecode
276
Disorders of fluid, electrolyte, and acid-base
Disorders of fluid, electrolyte, and acid-base balance
 Endocrine/metabolic 1.11 1.09 – 1.14 2.47e-18 7284 72932 all phecode
276.1 Electrolyte imbalance Endocrine/metabolic 1.09 1.06 – 1.13 4.22e-08 4086 40930 all phecode
276.11 Hyperosmolality and/or hypernatremia Endocrine/metabolic 0.983 0.862 – 1.12 0.797 239 2409 all phecode
276.12 Hyposmolality and/or hyponatremia Endocrine/metabolic 1.08 1.03 – 1.13 0.00202 1818 18200 all phecode
276.13 Hyperpotassemia Endocrine/metabolic 1.17 1.09 – 1.25 4.35e-06 969 9728 all phecode
276.14 Hypopotassemia Endocrine/metabolic 1.1 1.04 – 1.16 0.000432 1424 14235 all phecode
276.4 Acid-base balance disorder Endocrine/metabolic 1.19 1.12 – 1.26 1.45e-08 1161 11629 all phecode
276.41 Acidosis Endocrine/metabolic 1.18 1.11 – 1.26 1.77e-07 1056 10577 all phecode
276.42 Alkalosis Endocrine/metabolic 1.16 0.963 – 1.41 0.117 113 1129 all phecode
276.5 Hypovolemia Endocrine/metabolic 1.1 1.06 – 1.15 9.72e-07 2827 28265 all phecode
276.6 Fluid overload Endocrine/metabolic 1.23 1.12 – 1.36 2.14e-05 451 4535 all phecode
276.8 Polydipsia Endocrine/metabolic 1.07 0.894 – 1.28 0.465 128 1278 all phecode
277 Other disorders of metabolism Endocrine/metabolic 1.11 1.04 – 1.19 0.00242 899 8977 all phecode
277.4 Disorders of bilirubin excretion Endocrine/metabolic 1.04 0.934 – 1.16 0.472 362 3613 all phecode
277.5 Other disorders of lipoid metabolism Endocrine/metabolic 1.12 0.975 – 1.28 0.111 230 2298 all phecode
277.51 Lipoprotein disorders Endocrine/metabolic 1.23 0.923 – 1.64 0.157 52 520 all phecode
278 Overweight, obesity and other hyperalimentation Endocrine/metabolic 1.22 1.19 – 1.24 2.38e-84 10804 108289 all phecode
278.1 Obesity Endocrine/metabolic 1.22 1.2 – 1.24 1.75e-84 10642 106670 all phecode
278.3 Localized adiposity Endocrine/metabolic 1.2 0.959 – 1.51 0.11 84 838 all phecode
278.4 Abnormal weight gain Endocrine/metabolic 1.24 0.975 – 1.58 0.0789 66 660 all phecode
279 Disorders involving the immune mechanism Endocrine/metabolic 1.03 0.905 – 1.17 0.665 250 2510 all phecode
279.1 Immunity deficiency Endocrine/metabolic 1.06 0.922 – 1.22 0.412 209 2100 all phecode
279.11 Deficiency of humoral immunity Endocrine/metabolic 1.05 0.886 – 1.24 0.575 138 1390 all phecode
279.7 Other immunological findings Endocrine/metabolic 1.03 0.91 – 1.18 0.607 248 2478 all phecode
280 Iron deficiency anemias Hematopoietic 1.06 1.03 – 1.08 3.06e-06 7610 76168 all phecode
280.1
Iron deficiency anemias, unspecified or not due
Iron deficiency anemias, unspecified or not due to blood loss
 Hematopoietic 1.06 1.04 – 1.09 1.24e-06 7311 73153 all phecode
280.2
Iron deficiency anemia secondary to blood loss
Iron deficiency anemia secondary to blood loss (chronic)
 Hematopoietic 0.998 0.906 – 1.1 0.975 452 4541 all phecode
281 Other deficiency anemia Hematopoietic 1.16 1.09 – 1.24 1.72e-06 1112 11126 all phecode
281.1 Megaloblastic anemia Hematopoietic 1.15 1.08 – 1.22 1.44e-05 1066 10669 all phecode
281.11 Pernicious anemia Hematopoietic 1.22 1.13 – 1.31 2.89e-07 750 7514 all phecode
281.12 Other vitamin B12 deficiency anemia Hematopoietic 1.01 0.866 – 1.17 0.915 177 1769 all phecode
281.13 Folate-deficiency anemia Hematopoietic 1.1 0.945 – 1.28 0.221 183 1836 all phecode
281.9 Deficiency anemias Hematopoietic 1.27 0.962 – 1.67 0.0927 54 538 all phecode
282 Hereditary hemolytic anemias Hematopoietic 1.18 0.996 – 1.4 0.0553 150 1499 all phecode
282.8 Other hemoglobinopathies Hematopoietic 1.13 0.861 – 1.49 0.377 56 560 all phecode
282.9 Other hereditary hemolytic anemias Hematopoietic 1.18 0.947 – 1.47 0.142 85 849 all phecode
283 Acquired hemolytic anemias Hematopoietic 1.06 0.887 – 1.27 0.507 135 1377 all phecode
283.1 Autoimmune hemolytic anemias Hematopoietic 1.13 0.919 – 1.38 0.252 103 1059 all phecode
284 Aplastic anemia Hematopoietic 1.04 0.942 – 1.15 0.447 435 4357 all phecode
285 Other anemias Hematopoietic 1.07 1.05 – 1.09 1.6e-11 12104 121094 all phecode
285.1 Acute posthemorrhagic anemia Hematopoietic 1.05 0.926 – 1.2 0.432 271 2707 all phecode
285.2 Anemia of chronic disease Hematopoietic 1.11 1.03 – 1.2 0.00848 697 6980 all phecode
285.22 Anemia in neoplastic disease Hematopoietic 1.08 0.977 – 1.2 0.13 414 4147 all phecode
286 Coagulation defects Hematopoietic 1.08 1.01 – 1.15 0.0283 921 9218 all phecode
286.1 Congenital coagulation defects Hematopoietic 1.08 0.98 – 1.19 0.121 459 4594 all phecode
286.11 Von willebrand's disease Hematopoietic 0.967 0.78 – 1.2 0.758 96 959 all phecode
286.12
Congenital deficiency of other clotting factors
Congenital deficiency of other clotting factors (including factor VII)
 Hematopoietic 1.16 1.03 – 1.3 0.0147 294 2944 all phecode
286.13 Congenital factor VIII disorder Hematopoietic 1.15 0.887 – 1.48 0.297 63 630 all phecode
286.5
Hemorrhagic disorder due to intrinsic
Hemorrhagic disorder due to intrinsic circulating anticoagulants
 Hematopoietic 1.26 1.02 – 1.57 0.0316 86 860 all phecode
286.7 Other and unspecified coagulation defects Hematopoietic 1.08 0.973 – 1.2 0.147 386 3867 all phecode
287 Purpura and other hemorrhagic conditions Hematopoietic 1.02 0.973 – 1.08 0.365 1652 16532 all phecode
287.1 Spontaneous ecchymoses Hematopoietic 1.05 0.877 – 1.26 0.594 129 1290 all phecode
287.2 Allergic purpura Hematopoietic 0.864 0.644 – 1.16 0.331 51 510 all phecode
287.3 Thrombocytopenia Hematopoietic 1.03 0.976 – 1.08 0.287 1553 15543 all phecode
287.31 Primary thrombocytopenia Hematopoietic 1.06 0.963 – 1.17 0.226 419 4195 all phecode
287.32 Secondary thrombocytopenia Hematopoietic 0.812 0.637 – 1.03 0.092 75 749 all phecode
288 Diseases of white blood cells Hematopoietic 0.996 0.963 – 1.03 0.827 3765 37672 all phecode
288.1 Decreased white blood cell count Hematopoietic 0.986 0.951 – 1.02 0.461 3168 31704 all phecode
288.11 Neutropenia Hematopoietic 0.987 0.951 – 1.02 0.47 3176 31784 all phecode
288.3 Eosinophilia Hematopoietic 0.903 0.708 – 1.15 0.409 71 709 all phecode
289 Other diseases of blood and blood-forming organs Hematopoietic 1.11 1.04 – 1.19 0.00303 862 8625 all phecode
289.3
Personal history of diseases of blood and
Personal history of diseases of blood and blood-forming organs
 Hematopoietic 1.07 0.951 – 1.21 0.255 290 2897 all phecode
289.4 Lymphadenitis Hematopoietic 1.12 1.07 – 1.16 1.54e-07 2602 26061 all phecode
289.5 Diseases of spleen Hematopoietic 1.04 0.945 – 1.13 0.458 516 5153 all phecode
289.8 Polycythemia, secondary Hematopoietic 1.17 1.04 – 1.32 0.00937 292 2917 all phecode
289.9 Abnormality of red blood cells Hematopoietic 1.21 0.969 – 1.5 0.0936 90 900 all phecode
290
Delirium dementia and amnestic and other
Delirium dementia and amnestic and other cognitive disorders
 Mental Disorders 1.09 1.04 – 1.14 0.000243 1929 19281 all phecode
290.1 Dementias Mental Disorders 1.08 1.01 – 1.15 0.022 1004 10032 all phecode
290.11 Alzheimer's disease Mental Disorders 1.07 0.973 – 1.18 0.157 431 4307 all phecode
290.16 Vascular dementia Mental Disorders 1.03 0.894 – 1.19 0.677 201 2008 all phecode
290.2 Delirium due to conditions classified elsewhere Mental Disorders 1.01 0.935 – 1.1 0.741 650 6501 all phecode
290.3
Other persistent mental disorders due to
Other persistent mental disorders due to conditions classified elsewhere
 Mental Disorders 1.68 1.31 – 2.16 4.88e-05 70 709 all phecode
291
Other specified nonpsychotic and/or transient
Other specified nonpsychotic and/or transient mental disorders
 Mental Disorders 1.14 1.07 – 1.23 0.000182 836 8385 all phecode
291.1
Transient mental disorders due to conditions
Transient mental disorders due to conditions classified elsewhere
 Mental Disorders 1.08 0.903 – 1.28 0.413 132 1320 all phecode
291.4
Specific nonpsychotic mental disorders due to
Specific nonpsychotic mental disorders due to brain damage
 Mental Disorders 1.12 0.992 – 1.27 0.068 286 2867 all phecode
291.8 Alteration of consciousness Mental Disorders 1.18 1.07 – 1.3 0.000996 436 4376 all phecode
292 Neurological disorders Mental Disorders 1.06 1.03 – 1.1 5.19e-05 4621 46260 all phecode
292.1 Aphasia/speech disturbance Mental Disorders 1.09 1.03 – 1.15 0.002 1504 15074 all phecode
292.2 Mild cognitive impairment Mental Disorders 0.994 0.854 – 1.16 0.942 190 1907 all phecode
292.3 Memory loss Mental Disorders 1.03 0.949 – 1.11 0.523 696 6978 all phecode
292.4 Altered mental status Mental Disorders 1.06 1.02 – 1.11 0.00805 2181 21827 all phecode
292.6 Hallucinations Mental Disorders 1.05 0.94 – 1.18 0.368 307 3073 all phecode
293 Symptoms involving head and neck Mental Disorders 1.13 1.08 – 1.18 8.79e-08 2078 20779 all phecode
293.1
Swelling, mass, or lump in head and neck
Swelling, mass, or lump in head and neck [Space-occupying lesion, intracranial NOS]
 Mental Disorders 1.13 1.06 – 1.21 0.000464 901 9010 all phecode
295 Schizophrenia and other psychotic disorders Mental Disorders 1.15 1.07 – 1.23 0.000135 841 8446 all phecode
295.1 Schizophrenia Mental Disorders 1.15 1.06 – 1.26 0.00107 574 5766 all phecode
295.2 Paranoid disorders Mental Disorders 1.17 1.01 – 1.36 0.0379 178 1780 all phecode
295.3 Psychosis Mental Disorders 0.943 0.802 – 1.11 0.484 169 1710 all phecode
296 Mood disorders Mental Disorders 1.21 1.19 – 1.23 2.55e-91 12372 123822 all phecode
296.1 Bipolar Mental Disorders 1.17 1.09 – 1.24 1.94e-06 1059 10599 all phecode
296.2 Depression Mental Disorders 1.21 1.19 – 1.24 1.03e-88 11737 117469 all phecode
296.22 Major depressive disorder Mental Disorders 1.09 0.979 – 1.22 0.113 361 3604 all phecode
297.2 Suicide or self-inflicted injury Mental Disorders 1.38 1.23 – 1.55 1.01e-07 311 3070 all phecode
300 Anxiety disorders Mental Disorders 1.13 1.11 – 1.16 4.57e-23 6844 68484 all phecode
300.1 Anxiety disorder Mental Disorders 1.14 1.11 – 1.17 1.1e-21 6324 63282 all phecode
300.11 Generalized anxiety disorder Mental Disorders 0.993 0.838 – 1.18 0.934 149 1499 all phecode
300.12 Agorophobia, social phobia, and panic disorder Mental Disorders 1.13 1.04 – 1.22 0.00239 707 7065 all phecode
300.13 Phobia Mental Disorders 1.17 1.06 – 1.28 0.0012 501 5013 all phecode
300.3 Obsessive-compulsive disorders Mental Disorders 1.03 0.865 – 1.22 0.766 140 1407 all phecode
300.4 Dysthymic disorder Mental Disorders 1.13 0.867 – 1.48 0.362 53 530 all phecode
300.8 Acute reaction to stress Mental Disorders 1.26 1.05 – 1.5 0.0124 124 1238 all phecode
300.9 Posttraumatic stress disorder Mental Disorders 1.18 0.972 – 1.42 0.0959 113 1129 all phecode
301 Personality disorders Mental Disorders 1.31 1.17 – 1.47 2.81e-06 334 3338 all phecode
301.2 Antisocial/borderline personality disorder Mental Disorders 1.29 1.07 – 1.56 0.00811 119 1186 all phecode
302 Sexual and gender identity disorders Mental Disorders 1.2 1.06 – 1.35 0.00419 283 2845 all phecode
303 Psychogenic and somatoform disorders Mental Disorders 1.1 0.998 – 1.21 0.0562 467 4679 all phecode
303.3 Psychogenic disorder Mental Disorders 1.07 0.955 – 1.19 0.256 350 3510 all phecode
303.4 Somatoform disorder Mental Disorders 1.18 0.985 – 1.42 0.0721 123 1229 all phecode
304 Adjustment reaction Mental Disorders 1.29 1.15 – 1.45 2.14e-05 293 2936 all phecode
305.2 Eating disorder Mental Disorders 0.908 0.733 – 1.12 0.374 90 900 all phecode
306 Other mental disorder Mental Disorders 1.41 1.39 – 1.43 5.52e-611 28056 230087 all phecode
306.9 Tension headache Mental Disorders 1.08 0.967 – 1.21 0.167 315 3148 all phecode
313 Pervasive developmental disorders Mental Disorders 1.18 0.938 – 1.48 0.159 76 770 all phecode
313.3 Autism Mental Disorders 1.18 0.903 – 1.54 0.228 53 539 all phecode
315 Develomental delays and disorders Mental Disorders 1.18 1.06 – 1.32 0.00282 351 3517 all phecode
315.1 Learning disorder Mental Disorders 1.15 0.985 – 1.35 0.0767 161 1610 all phecode
315.2 Speech and language disorder Mental Disorders 1.1 0.883 – 1.37 0.399 88 880 all phecode
316 Substance addiction and disorders Mental Disorders 1.36 1.32 – 1.4 3.27e-99 5313 53131 all phecode
316.1 Polyneuropathy due to drugs Mental Disorders 1.07 0.835 – 1.38 0.58 60 599 all phecode
317 Alcohol-related disorders Mental Disorders 1.25 1.23 – 1.27 7.21e-124 12696 126892 all phecode
317.1 Alcoholism Mental Disorders 1.22 1.19 – 1.25 3.85e-71 8890 88923 all phecode
317.11 Alcoholic liver damage Mental Disorders 1.39 1.29 – 1.49 3.74e-19 838 8392 all phecode
318 Tobacco use disorder Mental Disorders 1.58 1.55 – 1.6 1.12e-756 19359 185465 all phecode
320 Meningitis Neurological 1.14 1.03 – 1.25 0.00868 444 4447 all phecode
323 Encephalitis Neurological 1.01 0.905 – 1.13 0.827 342 3422 all phecode
323.2 Acute (transverse) myelitis Neurological 0.998 0.785 – 1.27 0.988 74 739 all phecode
324 Other CNS infection and poliomyelitis Neurological 1.01 0.893 – 1.13 0.927 292 2916 all phecode
327 Sleep disorders Neurological 1.15 1.09 – 1.23 3.19e-06 1164 11659 all phecode
327.3 Sleep apnea Neurological 1.17 1.13 – 1.21 3.09e-23 4428 44318 all phecode
327.4 Insomnia Neurological 1.24 1.06 – 1.46 0.00912 163 1660 all phecode
327.41 Organic or persistent insomnia Neurological 1.23 1.03 – 1.46 0.0248 136 1390 all phecode
331 Other cerebral degenerations Neurological 1.11 1.04 – 1.17 0.0012 1142 11416 all phecode
331.1 Hydrocephalus Neurological 1.15 1.05 – 1.26 0.00329 502 5014 all phecode
331.9 Cerebral degeneration, unspecified Neurological 1.09 0.991 – 1.2 0.0757 430 4298 all phecode
332 Parkinson's disease Neurological 0.952 0.896 – 1.01 0.113 1126 11254 all phecode
333
Extrapyramidal disease and abnormal movement
Extrapyramidal disease and abnormal movement disorders
 Neurological 1.07 0.998 – 1.15 0.0566 894 8954 all phecode
333.1 Essential tremor Neurological 1.02 0.887 – 1.18 0.769 216 2157 all phecode
333.2 Myoclonus Neurological 1.06 0.856 – 1.32 0.587 96 958 all phecode
333.4 Torsion dystonia Neurological 1.03 0.905 – 1.18 0.648 253 2528 all phecode
334 Degenerative disease of the spinal cord Neurological 1.09 1.04 – 1.14 0.000752 1812 18130 all phecode
334.1 Spinocerebellar disease Neurological 0.942 0.78 – 1.14 0.534 117 1169 all phecode
334.2 Anterior horn cell disease Neurological 0.956 0.837 – 1.09 0.504 245 2446 all phecode
335 Multiple sclerosis Neurological 1.02 0.968 – 1.08 0.411 1340 13385 all phecode
337 Disorders of the autonomic nervous system Neurological 1.05 0.929 – 1.2 0.411 266 2668 all phecode
337.1 Peripheral autonomic neuropathy Neurological 1.06 0.837 – 1.35 0.624 72 719 all phecode
338 Pain Neurological 1.22 1.13 – 1.32 1.13e-07 768 7692 all phecode
338.1 Acute pain Neurological 1.24 1.11 – 1.38 6.53e-05 394 3937 all phecode
338.2 Chronic pain Neurological 1.21 1.09 – 1.35 0.000294 380 3817 all phecode
339 Other headache syndromes Neurological 1.11 1.09 – 1.14 3.17e-19 7819 78241 all phecode
340 Migraine Neurological 1.08 1.04 – 1.12 0.00011 2860 28602 all phecode
340.1 Migrain with aura Neurological 1.11 0.967 – 1.28 0.138 212 2117 all phecode
341
Other demyelinating diseases of central nervous
Other demyelinating diseases of central nervous system
 Neurological 1.09 0.952 – 1.24 0.216 252 2535 all phecode
342 Hemiplegia Neurological 1.12 1.06 – 1.18 3.37e-05 1494 14947 all phecode
343 Infantile cerebral palsy Neurological 1 0.846 – 1.19 0.98 145 1450 all phecode
344 Other paralytic syndromes Neurological 1.17 1.08 – 1.26 0.000182 658 6593 all phecode
345 Epilepsy, recurrent seizures, convulsions Neurological 1.09 1.06 – 1.13 9.91e-10 5023 50270 all phecode
345.1 Epilepsy Neurological 1.08 1 – 1.15 0.0407 866 8661 all phecode
345.11 Generalized convulsive epilepsy Neurological 1.04 0.945 – 1.15 0.412 439 4385 all phecode
345.12 Partial epilepsy Neurological 0.985 0.87 – 1.11 0.809 277 2776 all phecode
345.3 Convulsions Neurological 1.05 1.01 – 1.1 0.0167 2235 22339 all phecode
346.1
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of skull and head
 Neurological 1.11 0.938 – 1.31 0.225 144 1438 all phecode
348 Other conditions of brain Neurological 1.12 1.05 – 1.21 0.00164 778 7808 all phecode
348.2 Cerebral edema and compression of brain Neurological 1.22 1.08 – 1.39 0.00163 268 2678 all phecode
348.4 Cerebral cysts Neurological 0.926 0.776 – 1.11 0.398 133 1350 all phecode
348.7 Coma Neurological 1.04 0.932 – 1.15 0.502 358 3596 all phecode
348.8 Encephalopathy, not elsewhere classified Neurological 1.15 1.01 – 1.31 0.0375 249 2504 all phecode
348.9 Other conditions of brain, NOS Neurological 1.05 0.948 – 1.16 0.349 390 3899 all phecode
349
Other and unspecified disorders of the nervous
Other and unspecified disorders of the nervous system
 Neurological 1.18 1.05 – 1.31 0.0039 342 3414 all phecode
350 Abnormal movement Neurological 1.11 1.06 – 1.15 6.64e-07 2671 26722 all phecode
350.1 Abnormal involuntary movements Neurological 1.14 1.06 – 1.22 0.000341 887 8852 all phecode
350.2 Abnormality of gait Neurological 1.09 1.03 – 1.15 0.00108 1596 15969 all phecode
350.3 Lack of coordination Neurological 1.08 0.965 – 1.2 0.185 363 3638 all phecode
350.6 Disturbances of sensation of smell and taste Neurological 0.931 0.706 – 1.23 0.611 54 540 all phecode
351 Other peripheral nerve disorders Neurological 1.14 1.12 – 1.17 3.59e-46 12420 124321 all phecode
352 Disorders of other cranial nerves Neurological 1.12 1.06 – 1.18 7.19e-05 1370 13706 all phecode
352.1 Trigeminal nerve disorders [CN5] Neurological 1.09 0.987 – 1.19 0.0922 463 4638 all phecode
352.2 Facial nerve disorders [CN7] Neurological 1.16 1.08 – 1.24 3.85e-05 880 8795 all phecode
353 Nerve root and plexus disorders Neurological 1.19 1.12 – 1.26 2.62e-08 1131 11319 all phecode
353.1 Nerve plexus lesions Neurological 1.07 0.879 – 1.29 0.519 114 1138 all phecode
353.2 Nerve root lesions Neurological 1.24 0.945 – 1.62 0.12 57 570 all phecode
356 Hereditary and idiopathic peripheral neuropathy Neurological 1.09 0.923 – 1.29 0.303 152 1520 all phecode
357 Inflammatory and toxic neuropathy Neurological 1.08 1.02 – 1.14 0.00785 1361 13648 all phecode
358 Myoneural disorders Neurological 0.96 0.835 – 1.1 0.56 211 2109 all phecode
358.1 Myasthenia gravis Neurological 0.966 0.834 – 1.12 0.645 192 1919 all phecode
359 Muscular dystrophies and other myopathies Neurological 1.04 0.944 – 1.14 0.445 465 4646 all phecode
359.1 Muscular dystrophies Neurological 1.09 0.906 – 1.31 0.362 122 1219 all phecode
359.2 Myopathy Neurological 1.06 0.953 – 1.18 0.285 360 3597 all phecode
360 Disorders of the globe Sense Organs 0.926 0.827 – 1.04 0.18 337 3367 all phecode
360.2 Progressive myopia Sense Organs 0.858 0.753 – 0.977 0.021 251 2508 all phecode
361 Retinal detachments and defects Sense Organs 0.942 0.909 – 0.977 0.00124 3246 32453 all phecode
361.1 Retinal detachment with retinal defect Sense Organs 0.936 0.886 – 0.989 0.0192 1389 13884 all phecode
361.2 Retinoschisis and retinal cysts Sense Organs 0.907 0.706 – 1.17 0.447 68 680 all phecode
362 Other retinal disorders Sense Organs 1.03 1 – 1.07 0.0481 3836 38370 all phecode
362.2
Degeneration of macula and posterior pole of
Degeneration of macula and posterior pole of retina
 Sense Organs 1.05 1 – 1.09 0.0465 2182 21813 all phecode
362.29 Macular degeneration (senile) of retina NOS Sense Organs 1.04 1 – 1.09 0.0524 2179 21783 all phecode
362.3 Other nondiabetic retinopathy Sense Organs 0.946 0.804 – 1.11 0.502 161 1609 all phecode
362.31 Separation of retinal layers Sense Organs 0.818 0.663 – 1.01 0.0623 99 990 all phecode
362.4 Retinal vascular changes and abnomalities Sense Organs 1.02 0.949 – 1.09 0.602 848 8477 all phecode
362.6 Peripheral retinal degenerations Sense Organs 0.97 0.833 – 1.13 0.695 182 1827 all phecode
362.7 Hereditary retinal dystrophies Sense Organs 1.04 0.835 – 1.29 0.741 82 812 all phecode
362.8 Retinal hemorrhage/ischemia Sense Organs 1.12 0.921 – 1.36 0.256 116 1159 all phecode
363
Chorioretinal inflammations, scars, and other
Chorioretinal inflammations, scars, and other disorders of choroid
 Sense Organs 0.893 0.766 – 1.04 0.149 170 1699 all phecode
363.3 Chorioretinal scars Sense Organs 0.797 0.627 – 1.01 0.0624 69 690 all phecode
364 Corneal opacity and other disorders of cornea Sense Organs 0.996 0.919 – 1.08 0.922 647 6485 all phecode
364.1 Corneal opacity Sense Organs 1.1 0.888 – 1.35 0.393 90 910 all phecode
364.2 Corneal edema Sense Organs 1.16 0.921 – 1.46 0.21 79 800 all phecode
364.4 Corneal degenerations Sense Organs 0.877 0.759 – 1.01 0.0752 201 2017 all phecode
364.41 Keratoconus Sense Organs 0.829 0.668 – 1.03 0.0881 86 869 all phecode
364.5 Corneal dystrophy Sense Organs 1.12 0.974 – 1.29 0.111 211 2109 all phecode
364.9 Cornea replaced by transplant Sense Organs 1.2 0.984 – 1.47 0.0708 100 1000 all phecode
365 Glaucoma Sense Organs 1.01 0.976 – 1.04 0.683 4408 44136 all phecode
365.1 Open-angle glaucoma Sense Organs 0.928 0.869 – 0.99 0.0237 1032 10346 all phecode
365.11 Primary open angle glaucoma Sense Organs 0.924 0.866 – 0.987 0.0179 1026 10287 all phecode
365.2 Primary angle-closure glaucoma Sense Organs 1.02 0.948 – 1.11 0.547 698 6996 all phecode
366 Cataract Sense Organs 1.05 1.03 – 1.06 1.48e-09 19926 168711 all phecode
366.1 Nonsenile Cataract Sense Organs 1.15 0.899 – 1.46 0.272 69 700 all phecode
366.2 Senile cataract Sense Organs 1.06 1.03 – 1.08 1.06e-06 8231 81909 all phecode
366.3 Traumatic cataract Sense Organs 0.861 0.703 – 1.06 0.151 102 1019 all phecode
367
Disorders of refraction and accommodation
Disorders of refraction and accommodation; blindness and low vision
 Sense Organs 1.05 1 – 1.09 0.0323 2408 24092 all phecode
367.1 Myopia Sense Organs 0.966 0.911 – 1.02 0.242 1251 12519 all phecode
367.2 Astigmatism Sense Organs 1.2 1.04 – 1.39 0.0141 190 1899 all phecode
367.8 Hypermetropia Sense Organs 1.24 1.09 – 1.41 0.00126 253 2530 all phecode
367.9 Blindness and low vision Sense Organs 1.13 1.05 – 1.22 0.00186 719 7198 all phecode
368 Visual disturbances Sense Organs 1.06 1.02 – 1.1 0.00289 2962 29648 all phecode
368.1 Amblyopia Sense Organs 1.07 0.976 – 1.16 0.158 532 5322 all phecode
368.2 Diplopia and disorders of binocular vision Sense Organs 1.09 1.01 – 1.18 0.0249 727 7288 all phecode
368.3 Anisometropia Sense Organs 0.976 0.827 – 1.15 0.774 154 1548 all phecode
368.4 Visual field defects Sense Organs 1.06 0.945 – 1.19 0.321 333 3327 all phecode
368.9 Subjective visual disturbances Sense Organs 1.09 1 – 1.18 0.0481 612 6115 all phecode
369 Infection of the eye Sense Organs 0.964 0.884 – 1.05 0.409 553 5544 all phecode
369.2 Eye infection, viral Sense Organs 0.899 0.749 – 1.08 0.249 125 1257 all phecode
369.5 Conjunctivitis, infectious Sense Organs 0.912 0.791 – 1.05 0.204 213 2128 all phecode
370 Keratitis Sense Organs 1.11 0.977 – 1.26 0.109 286 2855 all phecode
370.1 Corneal ulcer Sense Organs 1.08 0.902 – 1.29 0.413 141 1408 all phecode
371 Inflammation of the eye Sense Organs 1.01 0.97 – 1.04 0.73 3045 30480 all phecode
371.1 Uveitis, noninfectious or NOS Sense Organs 0.981 0.893 – 1.08 0.682 482 4821 all phecode
371.3 Inflammation of eyelids Sense Organs 0.994 0.953 – 1.04 0.784 2353 23555 all phecode
372 Disorders of conjunctiva Sense Organs 1.1 1.02 – 1.18 0.0136 760 7602 all phecode
374 Other disorders of eyelids Sense Organs 1.06 1.03 – 1.09 1.32e-05 5680 56807 all phecode
374.1 Ectropion or entropion Sense Organs 1.08 1.01 – 1.15 0.02 1063 10645 all phecode
374.3 Ptosis of eyelid Sense Organs 1.06 1.01 – 1.11 0.0165 1825 18232 all phecode
375 Disorders of lacrimal system Sense Organs 1.06 1.02 – 1.11 0.00761 2204 22031 all phecode
375.2 Epiphora Sense Organs 1.04 0.975 – 1.12 0.214 898 8969 all phecode
376 Disorders of the orbit Sense Organs 1.07 0.856 – 1.34 0.548 86 859 all phecode
377 Disorders of optic nerve and visual pathways Sense Organs 1.05 0.941 – 1.17 0.398 361 3618 all phecode
377.1 Optic atrophy Sense Organs 0.991 0.744 – 1.32 0.951 56 570 all phecode
377.3 Optic neuritis/neuropathy Sense Organs 1.04 0.866 – 1.25 0.67 125 1249 all phecode
378
Strabismus and other disorders of binocular eye
Strabismus and other disorders of binocular eye movements
 Sense Organs 1.05 0.993 – 1.11 0.0908 1410 14116 all phecode
378.1 Strabismus (not specified as paralytic) Sense Organs 1.07 0.997 – 1.14 0.0599 909 9082 all phecode
378.2 Nystagmus and other irregular eye movements Sense Organs 1.07 0.929 – 1.23 0.358 213 2138 all phecode
378.5 Paralytic strabismus Sense Organs 1.01 0.894 – 1.14 0.874 275 2755 all phecode
379 Other disorders of eye Sense Organs 1.02 0.984 – 1.05 0.292 3703 37063 all phecode
379.2 Disorders of vitreous body Sense Organs 0.983 0.929 – 1.04 0.547 1367 13665 all phecode
379.3 Aphakia and other disorders of lens Sense Organs 1.05 1 – 1.1 0.0408 1813 18134 all phecode
379.4 Anomalies of pupillary function Sense Organs 0.913 0.727 – 1.15 0.433 71 710 all phecode
379.5 Disorders of iris and ciliary body Sense Organs 1.03 0.935 – 1.14 0.514 400 4028 all phecode
379.9 Pain, swelling or discharge of eye Sense Organs 1.1 0.94 – 1.29 0.232 169 1690 all phecode
380 Disorders of external ear Sense Organs 1.12 1.03 – 1.22 0.00572 642 6413 all phecode
380.1 Otitis externa Sense Organs 1.18 1.08 – 1.3 0.00038 509 5107 all phecode
380.4 Impacted cerumen Sense Organs 1.05 0.938 – 1.17 0.414 362 3614 all phecode
381 Otitis media and Eustachian tube disorders Sense Organs 1.15 1.1 – 1.2 1.1e-09 2150 21493 all phecode
381.1 Otitis media Sense Organs 1.13 1.08 – 1.19 1.31e-06 1767 17668 all phecode
381.11 Suppurative and unspecified otitis media Sense Organs 1.23 1.14 – 1.32 1.5e-08 852 8524 all phecode
381.2 Eustachian tube disorders Sense Organs 1.15 0.99 – 1.34 0.0678 193 1929 all phecode
381.3 Mastoiditis & related conditions Sense Organs 1.11 0.946 – 1.3 0.202 171 1709 all phecode
381.9 Otorrhea Sense Organs 1.31 1.16 – 1.48 2.12e-05 281 2807 all phecode
382 Otalgia Sense Organs 1.05 0.932 – 1.18 0.444 308 3084 all phecode
383 Otosclerosis Sense Organs 0.952 0.848 – 1.07 0.403 309 3090 all phecode
384 Other disorders of tympanic membrane Sense Organs 1.22 1.15 – 1.29 2.36e-11 1299 12991 all phecode
384.4 Perforation of tympanic membrane Sense Organs 1.2 1.12 – 1.28 3.38e-08 1043 10432 all phecode
385 Other disorders of middle ear and mastoid Sense Organs 1.14 1.06 – 1.23 0.000448 783 7837 all phecode
385.3 Cholesteatoma Sense Organs 1.15 1.05 – 1.25 0.00163 607 6078 all phecode
385.5
Tympanosclerosis and middle ear disease related
Tympanosclerosis and middle ear disease related to otitis media
 Sense Organs 1.15 1.01 – 1.31 0.0403 241 2409 all phecode
386
Vertiginous syndromes and other disorders of
Vertiginous syndromes and other disorders of vestibular system
 Sense Organs 1.07 1.02 – 1.12 0.00787 1736 17373 all phecode
386.1 Meniere's disease Sense Organs 1.04 0.957 – 1.14 0.328 576 5768 all phecode
386.2 Peripheral or central vertigo Sense Organs 1.04 0.935 – 1.16 0.471 377 3763 all phecode
386.3 Labyrinthitis Sense Organs 1.09 1.01 – 1.17 0.0278 765 7664 all phecode
386.9
Dizziness and giddiness (Light-headedness and
Dizziness and giddiness (Light-headedness and vertigo)
 Sense Organs 1.08 1.05 – 1.12 1.61e-07 4582 45806 all phecode
388 Other disorders of ear Sense Organs 1.2 1.03 – 1.39 0.0168 202 2017 all phecode
389 Hearing loss Sense Organs 1.09 1.05 – 1.12 1.59e-07 4188 41944 all phecode
389.1 Sensorineural hearing loss Sense Organs 1.05 0.953 – 1.15 0.326 456 4553 all phecode
389.2 Conductive hearing loss Sense Organs 1.07 0.971 – 1.18 0.176 450 4497 all phecode
389.4 Tinnitus Sense Organs 1.1 1 – 1.2 0.0439 513 5134 all phecode
394 Rheumatic disease of the heart valves Circulatory System 1.08 1.05 – 1.11 1.89e-07 4899 48974 all phecode
394.2 Mitral valve disease Circulatory System 1.07 1.03 – 1.11 0.000251 2993 29922 all phecode
394.3 Aortic valve disease Circulatory System 1.06 1 – 1.12 0.0483 1282 12814 all phecode
394.7 Disease of tricuspid valve Circulatory System 1.11 1.04 – 1.18 0.00125 1058 10566 all phecode
395 Heart valve disorders Circulatory System 1.08 1.05 – 1.12 1.23e-06 4223 42219 all phecode
395.1 Nonrheumatic mitral valve disorders Circulatory System 1.07 1.03 – 1.12 0.000268 2891 28900 all phecode
395.2 Nonrheumatic aortic valve disorders Circulatory System 1.13 1 – 1.28 0.0449 276 2766 all phecode
395.3 Nonrheumatic tricuspid valve disorders Circulatory System 1.1 0.897 – 1.34 0.366 105 1039 all phecode
395.4 Nonrheumatic pulmonary valve disorders Circulatory System 1.32 1.08 – 1.62 0.00754 97 970 all phecode
395.6 Heart valve replaced Circulatory System 1.07 1.01 – 1.13 0.0138 1495 14942 all phecode
396 Abnormal heart sounds Circulatory System 1.05 0.988 – 1.12 0.113 1048 10468 all phecode
401 Hypertension Circulatory System 1.11 1.1 – 1.12 4.59e-133 73956 266957 all phecode
401.1 Essential hypertension Circulatory System 1.11 1.1 – 1.12 4.27e-132 73731 266739 all phecode
401.2 Hypertensive heart and/or renal disease Circulatory System 1.17 1.11 – 1.22 1.06e-10 1898 19031 all phecode
401.21 Hypertensive heart disease Circulatory System 1.25 1.12 – 1.39 5.02e-05 370 3699 all phecode
401.22 Hypertensive chronic kidney disease Circulatory System 1.14 1.09 – 1.21 3.16e-07 1543 15483 all phecode
401.3 Other hypertensive complications Circulatory System 1.29 1.09 – 1.52 0.00314 144 1438 all phecode
402
Elevated blood pressure reading without
Elevated blood pressure reading without diagnosis of hypertension
 Circulatory System 1.1 1.05 – 1.16 0.000261 1479 14786 all phecode
411 Ischemic Heart Disease Circulatory System 1.14 1.13 – 1.16 2.12e-106 31245 210714 all phecode
411.1 Unstable angina (intermediate coronary syndrome) Circulatory System 1.2 1.16 – 1.23 3.72e-34 5152 51498 all phecode
411.2 Myocardial infarction Circulatory System 1.17 1.15 – 1.19 5.59e-61 11950 112699 all phecode
411.3 Angina pectoris Circulatory System 1.16 1.14 – 1.18 1.87e-72 15888 143745 all phecode
411.4 Coronary atherosclerosis Circulatory System 1.14 1.12 – 1.15 8.68e-66 20171 154621 all phecode
411.41 Aneurysm and dissection of heart Circulatory System 1.06 0.985 – 1.15 0.116 700 6997 all phecode
411.8
Other chronic ischemic heart disease
Other chronic ischemic heart disease, unspecified
 Circulatory System 1.19 1.17 – 1.21 9.28e-89 15290 131798 all phecode
411.9
Other acute and subacute forms of ischemic
Other acute and subacute forms of ischemic heart disease
 Circulatory System 1.16 1.09 – 1.23 1.33e-06 1218 12166 all phecode
414 Other forms of chronic heart disease Circulatory System 1.17 1.11 – 1.23 2.15e-10 1823 18228 all phecode
414.2 ASCVD Circulatory System 1.3 1.02 – 1.66 0.036 72 719 all phecode
415 Pulmonary heart disease Circulatory System 1.08 1.05 – 1.11 6.81e-07 4476 44810 all phecode
415.11 Pulmonary embolism and infarction, acute Circulatory System 0.936 0.746 – 1.17 0.566 75 750 all phecode
415.2 Chronic pulmonary heart disease Circulatory System 1.12 1.03 – 1.22 0.00839 601 6002 all phecode
415.21 Primary pulmonary hypertension Circulatory System 1.11 1.01 – 1.22 0.0273 448 4475 all phecode
416 Cardiomegaly Circulatory System 1.1 1.05 – 1.14 6.91e-06 2680 26793 all phecode
418 Nonspecific chest pain Circulatory System 1.12 1.11 – 1.14 7.46e-79 28599 270106 all phecode
418.1 Precordial pain Circulatory System 1.13 1.09 – 1.17 1.67e-11 3551 35541 all phecode
420 Carditis Circulatory System 1.07 1.02 – 1.11 0.00611 2106 21053 all phecode
420.1 Myocarditis Circulatory System 1.29 1.08 – 1.54 0.00559 127 1267 all phecode
420.2 Pericarditis Circulatory System 1.04 0.987 – 1.11 0.132 1338 13371 all phecode
420.21 Acute pericarditis Circulatory System 1.04 0.912 – 1.19 0.546 223 2227 all phecode
420.22 Chronic pericarditis Circulatory System 1.06 0.877 – 1.28 0.541 113 1129 all phecode
420.3 Endocarditis Circulatory System 1.08 1 – 1.17 0.042 719 7194 all phecode
425 Cardiomyopathy Circulatory System 1.13 1.06 – 1.19 5.28e-05 1271 12699 all phecode
425.1 Primary/intrinsic cardiomyopathies Circulatory System 1.12 1.06 – 1.19 0.000109 1236 12349 all phecode
425.11 Hypertrophic obstructive cardiomyopathy Circulatory System 1.03 0.86 – 1.22 0.779 133 1329 all phecode
425.12 Other hypertrophic cardiomyopathy Circulatory System 1.23 1.04 – 1.46 0.0144 163 1629 all phecode
425.8 Other cardiomyopathy Circulatory System 1.28 0.977 – 1.66 0.0732 60 600 all phecode
426 Cardiac conduction disorders Circulatory System 1.1 1.07 – 1.13 2.88e-14 6910 69146 all phecode
426.2 Atrioventricular [AV] block Circulatory System 1.08 1.03 – 1.13 0.000781 2114 21162 all phecode
426.21 First degree AV block Circulatory System 1.07 1.01 – 1.15 0.0297 986 9867 all phecode
426.23 Second degree AV block Circulatory System 1.04 0.94 – 1.14 0.473 452 4515 all phecode
426.24 Atrioventricular block, complete Circulatory System 1.1 1.01 – 1.2 0.0241 587 5868 all phecode
426.25 Other heart block Circulatory System 1.08 0.905 – 1.29 0.392 131 1318 all phecode
426.3 Bundle branch block Circulatory System 1.11 1.07 – 1.15 1.33e-08 3336 33359 all phecode
426.31 Right bundle branch block Circulatory System 1.09 1.04 – 1.15 0.000922 1494 14933 all phecode
426.32 Left bundle branch block Circulatory System 1.11 1.06 – 1.17 1.82e-05 1750 17503 all phecode
426.4 Anomalous atrioventricular excitation Circulatory System 1.17 1.03 – 1.34 0.0179 233 2328 all phecode
426.8 Other cardiac conduction disorders Circulatory System 1.12 0.859 – 1.46 0.403 60 600 all phecode
426.9 Cardiac pacemaker/device in situ Circulatory System 1.12 1.08 – 1.17 3.42e-08 2475 24774 all phecode
426.91 Cardiac pacemaker in situ Circulatory System 1.11 1.06 – 1.16 2.21e-06 2274 22762 all phecode
427 Cardiac dysrhythmias Circulatory System 1.08 1.07 – 1.1 1.51e-32 24207 206016 all phecode
427.1 Paroxysmal tachycardia, unspecified Circulatory System 1.09 1.05 – 1.13 1.76e-06 3199 32017 all phecode
427.11 Paroxysmal supraventricular tachycardia Circulatory System 1.11 1.06 – 1.16 2.7e-06 2344 23474 all phecode
427.12 Paroxysmal ventricular tachycardia Circulatory System 1.06 0.987 – 1.13 0.113 936 9365 all phecode
427.2 Atrial fibrillation and flutter Circulatory System 1.09 1.07 – 1.1 7.64e-21 14628 133501 all phecode
427.3 Other specified cardiac dysrhythmias Circulatory System 1.07 1.03 – 1.11 0.000332 3228 32281 all phecode
427.4 Cardiac arrest and ventricular fibrillation Circulatory System 1.16 1.09 – 1.23 8.25e-07 1193 11915 all phecode
427.41 Ventricular fibrillation and flutter Circulatory System 1.1 0.984 – 1.23 0.0932 344 3437 all phecode
427.42 Cardiac arrest Circulatory System 1.16 1.09 – 1.24 4.61e-06 990 9890 all phecode
427.5 Arrhythmia (cardiac) NOS Circulatory System 1.08 1.01 – 1.16 0.0173 952 9541 all phecode
427.6 Premature beats Circulatory System 1.11 1.02 – 1.22 0.0183 535 5358 all phecode
427.61 Supraventricular premature beats Circulatory System 1.08 0.898 – 1.29 0.42 117 1168 all phecode
427.7 Tachycardia NOS Circulatory System 1.12 1.07 – 1.17 1.26e-06 2185 21865 all phecode
427.8 Sinoatrial node dysfunction (Bradycardia) Circulatory System 1.11 1 – 1.23 0.0462 402 4029 all phecode
427.9 Palpitations Circulatory System 1.07 1.04 – 1.11 5.04e-05 3811 38105 all phecode
428 Congestive heart failure; nonhypertensive Circulatory System 1.17 1.13 – 1.2 1.13e-27 5605 56018 all phecode
428.1 Congestive heart failure (CHF) NOS Circulatory System 1.2 1.14 – 1.25 3.73e-15 2111 21108 all phecode
428.2 Heart failure NOS Circulatory System 1.15 1.12 – 1.19 1.14e-19 4455 44524 all phecode
429
Ill-defined descriptions and complications of
Ill-defined descriptions and complications of heart disease
 Circulatory System 1.09 1.01 – 1.17 0.0369 716 7168 all phecode
429.1 Heart transplant/surgery Circulatory System 0.963 0.75 – 1.24 0.77 64 639 all phecode
429.2 Abnormal function study of cardiovascular system Circulatory System 1.12 1.03 – 1.23 0.0113 522 5211 all phecode
429.3 Symptoms involving cardiovascular system Circulatory System 1.02 0.883 – 1.18 0.775 196 1978 all phecode
430 Intracranial hemorrhage Circulatory System 1.14 1.09 – 1.2 7.77e-08 1883 18825 all phecode
430.1 Subarachnoid hemorrhage Circulatory System 1.17 1.09 – 1.25 1.91e-05 836 8353 all phecode
430.2 Intracerebral hemorrhage Circulatory System 1.18 1.09 – 1.27 2.23e-05 765 7656 all phecode
430.3 Subdural hemorrhage Circulatory System 0.919 0.809 – 1.04 0.198 267 2667 all phecode
433 Cerebrovascular disease Circulatory System 1.12 1.09 – 1.14 1.91e-22 8749 87456 all phecode
433.1 Occlusion and stenosis of precerebral arteries Circulatory System 1.26 1.18 – 1.33 1.66e-13 1185 11825 all phecode
433.12 Cerebral atherosclerosis Circulatory System 1.19 1.04 – 1.37 0.0128 227 2267 all phecode
433.2 Occlusion of cerebral arteries Circulatory System 1.11 1.07 – 1.14 2.49e-10 4233 42320 all phecode
433.21
Cerebral artery occlusion, with cerebral
Cerebral artery occlusion, with cerebral infarction
 Circulatory System 1.11 1.06 – 1.17 4.44e-05 1680 16794 all phecode
433.3 Cerebral ischemia Circulatory System 1.12 1.08 – 1.17 2.58e-09 2895 28989 all phecode
433.31 Transient cerebral ischemia Circulatory System 1.11 1.06 – 1.16 6.48e-06 2135 21379 all phecode
433.5 Cerebral aneurysm Circulatory System 1.19 1.07 – 1.32 0.00103 394 3939 all phecode
433.8 Late effects of cerebrovascular disease Circulatory System 1.17 1.11 – 1.24 3.78e-08 1279 12783 all phecode
440 Atherosclerosis Circulatory System 1.32 1.24 – 1.39 1.48e-21 1380 13822 all phecode
440.1 Atherosclerosis of renal artery Circulatory System 1.2 0.981 – 1.48 0.0753 113 1129 all phecode
440.2 Atherosclerosis of the extremities Circulatory System 1.39 1.29 – 1.5 1.42e-18 805 8070 all phecode
440.9 Atherosclerosis of aorta Circulatory System 1.39 1.23 – 1.58 1.56e-07 287 2867 all phecode
441 Vascular insufficiency of intestine Circulatory System 1.19 1.09 – 1.29 4.4e-05 614 6154 all phecode
441.1 Acute vascular insufficiency of intestine Circulatory System 1.13 1 – 1.27 0.049 283 2827 all phecode
442 Other aneurysm Circulatory System 1.16 1.11 – 1.22 2.98e-10 1892 18959 all phecode
442.1 Aortic aneurysm Circulatory System 1.2 1.14 – 1.27 1.45e-11 1458 14625 all phecode
442.11 Abdominal aortic aneurysm Circulatory System 1.33 1.25 – 1.43 7.13e-17 931 9341 all phecode
442.2 Aneurysm of iliac artery Circulatory System 1.18 0.963 – 1.46 0.109 102 1019 all phecode
442.3 Aneurysm of artery of lower extremity Circulatory System 0.995 0.848 – 1.17 0.956 169 1696 all phecode
442.4 Arterial dissection Circulatory System 1.03 0.785 – 1.35 0.826 54 549 all phecode
442.8 Aneurysm of other specified artery Circulatory System 1.02 0.884 – 1.18 0.778 203 2028 all phecode
443 Peripheral vascular disease Circulatory System 1.23 1.19 – 1.28 2.92e-36 3921 39273 all phecode
443.1 Raynaud's syndrome Circulatory System 1.09 1.03 – 1.16 0.00375 1145 11438 all phecode
443.7
Peripheral angiopathy in diseases classified
Peripheral angiopathy in diseases classified elsewhere
 Circulatory System 1.09 0.983 – 1.21 0.0995 384 3878 all phecode
443.8 Other specified peripheral vascular diseases Circulatory System 1.25 1.21 – 1.29 1.56e-38 3686 36906 all phecode
443.9 Peripheral vascular disease, unspecified Circulatory System 1.32 1.27 – 1.38 9.55e-42 2579 25846 all phecode
444 Arterial embolism and thrombosis Circulatory System 1.31 1.23 – 1.4 4.52e-15 922 9251 all phecode
444.1
Arterial embolism and thrombosis of lower
Arterial embolism and thrombosis of lower extremity artery
 Circulatory System 1.31 1.2 – 1.43 6.15e-10 554 5552 all phecode
446 Polyarteritis nodosa and allied conditions Circulatory System 1.06 0.982 – 1.13 0.143 822 8226 all phecode
446.4 Wegener's granulomatosis Circulatory System 1.15 0.991 – 1.33 0.0649 188 1878 all phecode
446.5 Giant cell arteritis Circulatory System 0.948 0.854 – 1.05 0.317 388 3879 all phecode
446.9 Arteritis NOS Circulatory System 1.16 1.01 – 1.33 0.0336 239 2400 all phecode
447 Other disorders of arteries and arterioles Circulatory System 1.32 1.25 – 1.4 9.03e-22 1327 13316 all phecode
447.1 Stricture of artery Circulatory System 1.39 1.29 – 1.49 6.18e-20 868 8712 all phecode
448 Disease of capillaries Circulatory System 1.21 1.02 – 1.44 0.0331 142 1420 all phecode
450 Noninfectious disorders of lymphatic channels Circulatory System 1.07 0.987 – 1.15 0.106 704 7034 all phecode
451 Phlebitis and thrombophlebitis Circulatory System 1.08 1.04 – 1.11 5.67e-06 3955 39683 all phecode
451.2
Phlebitis and thrombophlebitis of lower
Phlebitis and thrombophlebitis of lower extremities
 Circulatory System 1.08 1.05 – 1.12 5.06e-06 3683 36977 all phecode
452 Other venous embolism and thrombosis Circulatory System 1.17 1.07 – 1.27 0.000474 564 5645 all phecode
454 Varicose veins Circulatory System 1.07 1.05 – 1.09 1.43e-12 11180 112047 all phecode
454.1 Varicose veins of lower extremity Circulatory System 1.07 1.05 – 1.09 1.7e-11 11503 115272 all phecode
454.11 Varicose veins of lower extremity, symptomtic Circulatory System 1.08 0.997 – 1.18 0.0597 624 6325 all phecode
455 Hemorrhoids Circulatory System 1.05 1.04 – 1.06 1.02e-12 23452 234585 all phecode
456 Chronic venous insufficiency [CVI] Circulatory System 1.02 0.883 – 1.19 0.755 184 1868 all phecode
457
Encounter for long-term (current) use of
Encounter for long-term (current) use of anticoagulants, antithrombotics, aspirin
 Circulatory System 0.788 0.646 – 0.962 0.019 97 967 all phecode
458 Hypotension Circulatory System 1.08 1.05 – 1.11 1.08e-07 5769 57772 all phecode
458.1 Orthostatic hypotension Circulatory System 1.02 0.963 – 1.08 0.518 1335 13376 all phecode
458.2 Iatrogenic hypotension Circulatory System 1.09 0.957 – 1.25 0.188 235 2348 all phecode
458.9 Hypotension NOS Circulatory System 1.1 1.06 – 1.14 1.87e-07 3494 35005 all phecode
459 Other disorders of circulatory system Circulatory System 1.13 1.11 – 1.14 2.63e-46 16268 160790 all phecode
459.1 Hemorrhage NOS Circulatory System 1.12 0.942 – 1.34 0.197 142 1420 all phecode
459.9 Circulatory disease NEC Circulatory System 1.13 1.11 – 1.14 1.44e-46 16103 159422 all phecode
464 Acute sinusitis Respiratory 1.29 1.12 – 1.5 0.000509 196 1957 all phecode
465
Acute upper respiratory infections of multiple
Acute upper respiratory infections of multiple or unspecified sites
 Respiratory 1.05 1.01 – 1.1 0.0157 2283 22827 all phecode
465.2 Acute pharyngitis Respiratory 1.08 1 – 1.16 0.0419 835 8348 all phecode
465.4 Acute laryngitis and tracheitis Respiratory 1.03 0.878 – 1.22 0.684 165 1649 all phecode
470 Septal Deviations/Turbinate Hypertrophy Respiratory 1.09 1.06 – 1.13 8.5e-09 4654 46553 all phecode
471 Nasal polyps Respiratory 1.05 1.01 – 1.09 0.00631 3297 32973 all phecode
472 Chronic pharyngitis and nasopharyngitis Respiratory 1.02 0.955 – 1.09 0.544 960 9594 all phecode
473 Diseases of the larynx and vocal cords Respiratory 1.2 1.15 – 1.25 7.75e-19 2554 25548 all phecode
473.1 Chronic laryngitis Respiratory 1.34 1.09 – 1.65 0.00519 104 1038 all phecode
473.3 Paralysis/spasm of vocal cords or larynx Respiratory 1.11 0.976 – 1.25 0.113 264 2647 all phecode
473.4 Voice disturbance Respiratory 1.17 1.09 – 1.24 1.65e-06 1080 10789 all phecode
474 Acute and chronic tonsillitis Respiratory 1.09 1.04 – 1.14 0.000833 1772 17710 all phecode
474.1 Acute tonsillitis Respiratory 1.13 1.04 – 1.24 0.00528 549 5486 all phecode
474.2 Chronic tonsillitis and adenoiditis Respiratory 1.11 1.04 – 1.18 0.00146 1122 11199 all phecode
475 Chronic sinusitis Respiratory 1.07 1.03 – 1.12 0.000617 2589 25882 all phecode
476 Allergic rhinitis Respiratory 0.967 0.908 – 1.03 0.29 1055 10563 all phecode
477 Epistaxis or throat hemorrhage Respiratory 1.11 1.07 – 1.16 6.26e-07 2447 24452 all phecode
478 Throat pain Respiratory 1.01 0.906 – 1.12 0.92 377 3789 all phecode
479 Other upper respiratory disease Respiratory 1.11 1.08 – 1.15 1.72e-10 4074 40737 all phecode
480 Pneumonia Respiratory 1.16 1.14 – 1.19 5.34e-48 10336 103397 all phecode
480.1 Bacterial pneumonia Respiratory 1.16 1.13 – 1.19 1.18e-31 6637 66410 all phecode
480.11 Pneumococcal pneumonia Respiratory 1.16 1.13 – 1.2 7.01e-29 5883 58863 all phecode
480.12 Pseudomonal pneumonia Respiratory 1.44 1.15 – 1.8 0.00141 93 929 all phecode
480.2 Viral pneumonia Respiratory 1.1 0.866 – 1.39 0.441 72 720 all phecode
480.3 Pneumonia due to fungus (mycoses) Respiratory 1.31 1.07 – 1.6 0.0087 99 989 all phecode
480.5 Bronchopneumonia and lung abscess Respiratory 1.18 1.1 – 1.27 1.11e-05 794 7951 all phecode
481 Influenza Respiratory 1.21 1.08 – 1.36 0.000915 328 3278 all phecode
483 Acute bronchitis and bronchiolitis Respiratory 1.33 1.15 – 1.55 0.000139 193 1930 all phecode
495 Asthma Respiratory 1.12 1.11 – 1.13 4.06e-66 25689 250406 all phecode
495.2 Asthma with exacerbation Respiratory 1.18 1.04 – 1.34 0.0108 250 2510 all phecode
496 Chronic airway obstruction Respiratory 1.39 1.36 – 1.42 1.1e-218 10424 101546 all phecode
496.1 Emphysema Respiratory 1.47 1.4 – 1.55 1.77e-52 1743 17438 all phecode
496.2 Chronic bronchitis Respiratory 1.49 1.43 – 1.54 1.97e-90 2947 29498 all phecode
496.21 Obstructive chronic bronchitis Respiratory 1.51 1.45 – 1.57 9.15e-89 2706 27081 all phecode
496.3 Bronchiectasis Respiratory 1.13 1.08 – 1.19 3.54e-07 1885 18859 all phecode
497 Bronchitis Respiratory 1.25 1.15 – 1.36 9.66e-08 626 6267 all phecode
500 Lung disease due to external agents Respiratory 1.34 1.21 – 1.49 3.77e-08 412 4099 all phecode
500.1 Extrinsic allergic alveolitis Respiratory 1.21 0.961 – 1.52 0.106 79 784 all phecode
500.2 Pneumoconiosis Respiratory 1.43 1.24 – 1.64 5e-07 243 2409 all phecode
501 Pneumonitis due to inhalation of food or vomitus Respiratory 1.08 1 – 1.17 0.0486 656 6557 all phecode
502 Postinflammatory pulmonary fibrosis Respiratory 1.2 1.12 – 1.28 2.21e-07 917 9193 all phecode
503 Pulmonary congestion and hypostasis Respiratory 1.29 1.17 – 1.41 6.93e-08 508 5079 all phecode
504 Other alveolar and parietoalveolar pneumonopathy Respiratory 1.19 1.06 – 1.33 0.00315 328 3280 all phecode
505 Other pulmonary inflamation or edema Respiratory 0.985 0.765 – 1.27 0.908 61 610 all phecode
506 Empyema and pneumothorax Respiratory 1.14 1.07 – 1.21 3.19e-05 1133 11362 all phecode
507 Pleurisy; pleural effusion Respiratory 1.1 1.07 – 1.13 1.59e-13 6419 64252 all phecode
508
Pulmonary collapse; interstitial and
Pulmonary collapse; interstitial and compensatory emphysema
 Respiratory 1.15 1.1 – 1.2 5.64e-09 1996 19947 all phecode
509 Respiratory failure, insufficiency, arrest Respiratory 1.22 1.17 – 1.27 1.78e-22 2599 26031 all phecode
509.1 Respiratory failure Respiratory 1.26 1.2 – 1.32 2.64e-23 2068 20708 all phecode
509.2 Respiratory insufficiency Respiratory 1.27 1.21 – 1.33 9.09e-22 1806 18106 all phecode
509.5 Respiratory arrest Respiratory 1.06 0.897 – 1.26 0.481 143 1429 all phecode
509.8
Dependence on respirator [Ventilator] or
Dependence on respirator [Ventilator] or supplemental oxygen
 Respiratory 1.15 1.03 – 1.28 0.00964 386 3863 all phecode
510 Other diseases of lung Respiratory 1.19 1.1 – 1.28 8.08e-06 755 7554 all phecode
512 Other symptoms of respiratory system Respiratory 1.13 1.11 – 1.16 8.09e-29 9031 90349 all phecode
512.1 Wheezing Respiratory 1.24 1.08 – 1.42 0.00191 220 2196 all phecode
512.2 Painful respiration Respiratory 1.24 1.07 – 1.43 0.00342 207 2075 all phecode
512.7 Shortness of breath Respiratory 1.15 1.12 – 1.18 8.22e-25 5842 58498 all phecode
512.8 Cough Respiratory 1.1 1.05 – 1.14 3.44e-06 2866 28642 all phecode
512.9 Other dyspnea Respiratory 1.13 1.06 – 1.21 0.000188 914 9124 all phecode
513 Respiratory abnormalities Respiratory 1.05 0.962 – 1.14 0.299 611 6112 all phecode
513.3 Hypoventilation Respiratory 1.15 0.922 – 1.43 0.217 83 830 all phecode
513.4 Hyperventilation Respiratory 1.05 0.929 – 1.19 0.429 278 2778 all phecode
513.8 Disorders of diaphragm Respiratory 0.988 0.836 – 1.17 0.884 153 1538 all phecode
514 Abnormal findings examination of lungs Respiratory 1.22 1.17 – 1.27 2.75e-20 2465 24673 all phecode
516 Abnormal sputum Respiratory 1.22 1.17 – 1.28 8.04e-19 2132 21335 all phecode
516.1 Hemoptysis Respiratory 1.22 1.17 – 1.28 2.43e-18 2073 20745 all phecode
519
Other diseases of respiratory system, not
Other diseases of respiratory system, not elsewhere classified
 Respiratory 1.14 1.12 – 1.16 1.85e-33 9366 93681 all phecode
519.2 Respiratory complications Respiratory 1.16 1.03 – 1.3 0.0123 327 3279 all phecode
519.8 Other diseases of respiratory system, NEC Respiratory 1.15 1.12 – 1.17 2.67e-34 8853 88522 all phecode
519.9
Symptoms involving respiratory system and other
Symptoms involving respiratory system and other chest symptoms
 Respiratory 0.979 0.87 – 1.1 0.717 303 3049 all phecode
520 Disorders of tooth development Digestive 0.995 0.95 – 1.04 0.818 2038 20354 all phecode
520.1 Hereditary disturbances in tooth structure Digestive 0.872 0.657 – 1.16 0.343 53 530 all phecode
520.2 Disturbances in tooth eruption Digestive 0.98 0.939 – 1.02 0.342 2356 23539 all phecode
521 Diseases of hard tissues of teeth Digestive 1.03 0.996 – 1.07 0.0802 3016 30245 all phecode
521.1 Dental caries Digestive 1.04 1 – 1.08 0.0412 3026 30353 all phecode
522 Diseases of pulp and periapical tissues Digestive 1.11 1.06 – 1.17 1.62e-05 1774 17750 all phecode
522.5 Periapical abscess Digestive 1.12 1.05 – 1.19 0.000327 1172 11731 all phecode
523 Gingival and periodontal diseases Digestive 1.07 1.01 – 1.12 0.014 1681 16812 all phecode
523.1 Gingivitis Digestive 1.15 0.952 – 1.38 0.148 113 1127 all phecode
523.3 Periodontitis (acute or chronic) Digestive 1.04 0.979 – 1.1 0.207 1165 11650 all phecode
523.31 Acute periodontitis Digestive 1.07 0.987 – 1.16 0.102 666 6667 all phecode
523.32 Chronic periodontitis Digestive 0.99 0.906 – 1.08 0.825 560 5594 all phecode
524 Dentofacial anomalies, including malocclusion Digestive 0.998 0.891 – 1.12 0.965 331 3307 all phecode
524.3 Anomalies of tooth position/malocclusion Digestive 0.953 0.848 – 1.07 0.425 305 3046 all phecode
525
Other diseases of the teeth and supporting
Other diseases of the teeth and supporting structures
 Digestive 1.08 1.03 – 1.12 0.000269 2668 26728 all phecode
525.2 Atrophy of edentulous alveolar ridge Digestive 1.21 0.946 – 1.55 0.129 72 720 all phecode
526 Diseases of the jaws Digestive 1.07 0.996 – 1.14 0.0651 928 9279 all phecode
526.1 Cysts of the jaws Digestive 0.988 0.882 – 1.11 0.842 329 3289 all phecode
526.3 Anomalies of jaw size/symmetry Digestive 1.14 0.883 – 1.47 0.317 61 610 all phecode
526.4 Temporomandibular joint disorders Digestive 1.2 1.05 – 1.37 0.00648 240 2406 all phecode
526.41 Temporomandibular joint disorder, unspecified Digestive 1.21 1.06 – 1.39 0.00488 233 2336 all phecode
526.5 Inflammatory conditions of jaw Digestive 1.1 0.897 – 1.34 0.364 110 1098 all phecode
526.9 Jaw disease NOS Digestive 1.01 0.882 – 1.16 0.883 233 2329 all phecode
527 Diseases of the salivary glands Digestive 1.1 1.01 – 1.19 0.0201 694 6943 all phecode
527.1 Hypertrophy of salivary gland Digestive 1.23 0.975 – 1.55 0.081 84 838 all phecode
527.2 Sialoadenitis Digestive 1.08 0.966 – 1.2 0.182 365 3656 all phecode
527.7 Disturbance of salivary secretion Digestive 1.08 0.832 – 1.41 0.557 62 619 all phecode
527.8 Other specified diseases of the salivary glands Digestive 1.06 0.878 – 1.28 0.543 120 1200 all phecode
528
Diseases of the oral soft tissues, excluding
Diseases of the oral soft tissues, excluding lesions specific for gingiva and tongue
 Digestive 1.11 1.07 – 1.15 9.31e-10 3873 38741 all phecode
528.1 Stomatitis and mucositis Digestive 1.04 0.95 – 1.15 0.371 468 4675 all phecode
528.11 Stomatitis and mucositis (ulcerative) Digestive 1.07 0.962 – 1.18 0.221 389 3884 all phecode
528.12 Oral aphthae Digestive 0.98 0.779 – 1.23 0.866 84 840 all phecode
528.3 Cellulitis and abscess of oral soft tissues Digestive 1.18 1.01 – 1.37 0.0399 179 1790 all phecode
528.4 Cysts of oral soft tissues Digestive 1.17 0.964 – 1.41 0.114 122 1219 all phecode
528.41 Cyst of the salivary gland Digestive 1.03 0.83 – 1.28 0.777 94 940 all phecode
528.5 Diseases of lips Digestive 1.06 0.981 – 1.15 0.138 681 6813 all phecode
528.6 Leukoplakia of oral mucosa Digestive 1.25 1.11 – 1.4 0.000226 308 3079 all phecode
528.7 Sialolithiasis Digestive 1.16 1.04 – 1.3 0.0104 314 3138 all phecode
529 Diseases and other conditions of the tongue Digestive 1.08 1.02 – 1.15 0.00904 1232 12312 all phecode
529.1 Glossitis Digestive 1.07 0.954 – 1.21 0.236 299 2986 all phecode
530 Diseases of esophagus Digestive 1.12 1.11 – 1.14 1.65e-89 33453 279172 all phecode
530.1 Esophagitis, GERD and related diseases Digestive 1.12 1.11 – 1.14 1.29e-83 31253 272429 all phecode
530.11 GERD Digestive 1.12 1.11 – 1.14 1.19e-62 22633 225879 all phecode
530.12 Ulcer of esophagus Digestive 1.12 1.09 – 1.16 9.59e-16 5203 52068 all phecode
530.14 Reflux esophagitis Digestive 1.13 1.11 – 1.15 2.45e-32 10444 104493 all phecode
530.2 Esophageal bleeding (varices/hemorrhage) Digestive 1.12 1.06 – 1.17 1.95e-05 1681 16808 all phecode
530.3 Stricture and stenosis of esophagus Digestive 1.07 1.02 – 1.12 0.00505 1869 18684 all phecode
530.5 Disorders of esophageal motility Digestive 1.08 0.992 – 1.17 0.0772 635 6365 all phecode
530.6 Diverticulum of esophagus, acquired Digestive 1.04 0.875 – 1.23 0.683 153 1527 all phecode
530.7 Gastroesophageal laceration-hemorrhage syndrome Digestive 1.21 1.08 – 1.35 0.000985 341 3416 all phecode
530.9 Heartburn Digestive 1.1 1.05 – 1.15 2.85e-05 2087 20881 all phecode
531 Peptic ulcer (excl. esophageal) Digestive 1.16 1.13 – 1.19 5.06e-33 7103 71066 all phecode
531.1 Hemorrhage from gastrointestinal ulcer Digestive 1.11 1.03 – 1.21 0.0104 637 6374 all phecode
531.2 Gastric ulcer Digestive 1.15 1.12 – 1.19 3.57e-18 4091 40941 all phecode
531.3 Duodenal ulcer Digestive 1.17 1.13 – 1.22 7.91e-17 2999 30005 all phecode
531.4 Peptic ulcer, site unspecified Digestive 1.25 1.13 – 1.38 1.12e-05 427 4268 all phecode
532 Dysphagia Digestive 1.12 1.09 – 1.15 1.79e-17 6427 64329 all phecode
535 Gastritis and duodenitis Digestive 1.12 1.11 – 1.14 1.58e-73 28078 261548 all phecode
535.1 Acute gastritis Digestive 1.08 1.02 – 1.15 0.0108 1183 11833 all phecode
535.2 Atrophic gastritis Digestive 1.11 0.993 – 1.23 0.0667 370 3687 all phecode
535.6 Duodenitis Digestive 1.15 1.12 – 1.18 2.71e-31 7592 75928 all phecode
535.8 Other specified gastritis Digestive 1.12 1.09 – 1.15 4.6e-22 8071 80763 all phecode
535.9 Gastritis and duodenitis, NOS Digestive 1.23 1.02 – 1.48 0.0319 120 1191 all phecode
536.8
Dyspepsia and other specified disorders of
Dyspepsia and other specified disorders of function of stomach
 Digestive 1.04 0.914 – 1.17 0.584 259 2576 all phecode
537 Other disorders of stomach and duodenum Digestive 1.12 1.08 – 1.16 1.19e-10 3391 33907 all phecode
540 Appendiceal conditions Digestive 1.02 0.986 – 1.06 0.219 3088 30890 all phecode
540.1 Appendicitis Digestive 1.03 0.988 – 1.07 0.173 2895 28963 all phecode
540.11 Acute appendicitis Digestive 1.01 0.969 – 1.05 0.678 2601 26019 all phecode
550 Abdominal hernia Digestive 1.08 1.07 – 1.09 2.6e-52 45429 282640 all phecode
550.1 Inguinal hernia Digestive 1.02 1 – 1.03 0.0357 15794 123247 all phecode
550.2 Diaphragmatic hernia Digestive 1.11 1.09 – 1.12 1.72e-54 26494 238953 all phecode
550.3 Femoral hernia Digestive 1.12 1.03 – 1.21 0.00601 651 6504 all phecode
550.4 Umbilical hernia Digestive 1.11 1.07 – 1.15 3.08e-09 3705 37072 all phecode
550.5 Ventral hernia Digestive 1.17 1.12 – 1.21 2.15e-17 3435 34338 all phecode
555
Inflammatory bowel disease and other
Inflammatory bowel disease and other gastroenteritis and colitis
 Digestive 1.1 1.07 – 1.14 3.31e-10 4444 44442 all phecode
555.1 Regional enteritis Digestive 1.1 1.05 – 1.16 8.34e-05 1734 17340 all phecode
555.2 Ulcerative colitis Digestive 1.09 1.05 – 1.13 1.63e-06 3178 31786 all phecode
555.21 Ulcerative colitis (chronic) Digestive 1.15 1.05 – 1.25 0.00221 538 5382 all phecode
556 Ulceration of the lower GI tract Digestive 1.17 1.09 – 1.24 2.15e-06 1055 10592 all phecode
556.1 Ulceration of intestine Digestive 1.26 1.16 – 1.37 2.33e-08 670 6714 all phecode
557 Intestinal malabsorption (non-celiac) Digestive 0.974 0.865 – 1.1 0.659 299 2987 all phecode
557.1 Celiac disease Digestive 0.865 0.824 – 0.907 3.6e-09 1837 18388 all phecode
558 Noninfectious gastroenteritis Digestive 1.1 1.08 – 1.11 4e-27 15492 155105 all phecode
559 Ileostomy status Digestive 1.06 1.01 – 1.12 0.0176 1656 16541 all phecode
560 Intestinal obstruction without mention of hernia Digestive 1.05 1.02 – 1.09 0.00209 3936 39337 all phecode
560.1 Paralytic ileus Digestive 1.01 0.919 – 1.1 0.892 523 5231 all phecode
560.2 Impaction of intestine Digestive 1.15 1.02 – 1.31 0.0274 268 2671 all phecode
560.3 Peritoneal or intestinal adhesions Digestive 1.06 0.99 – 1.14 0.09 832 8317 all phecode
560.4 Other intestinal obstruction Digestive 1.05 1.01 – 1.09 0.00625 3358 33550 all phecode
561 Symptoms involving digestive system Digestive 1.09 1.08 – 1.11 2.39e-26 15772 157686 all phecode
561.1 Diarrhea Digestive 1.09 0.994 – 1.2 0.0658 466 4653 all phecode
561.2 Flatulence Digestive 1.09 1.03 – 1.14 0.00098 1687 16859 all phecode
562 Diverticulosis and diverticulitis Digestive 1.09 1.08 – 1.11 2.48e-43 26714 211692 all phecode
562.1 Diverticulosis Digestive 1.09 1.08 – 1.11 1.71e-43 26672 211642 all phecode
563 Constipation Digestive 1.11 1.09 – 1.14 1.21e-25 10314 103140 all phecode
564 Functional digestive disorders Digestive 1.11 1.1 – 1.13 6.41e-50 21639 209949 all phecode
564.1 Irritable Bowel Syndrome Digestive 1.11 1.08 – 1.14 5.06e-14 5508 55117 all phecode
564.8
Abnormal findings on exam of gastrointestinal
Abnormal findings on exam of gastrointestinal tract/ abdominal area
 Digestive 1.07 1.02 – 1.12 0.0104 1645 16457 all phecode
564.9 Personal history of diseases of digestive system Digestive 1.12 1.11 – 1.14 3e-43 15186 151648 all phecode
565 Anal and rectal conditions Digestive 1.11 1.09 – 1.13 2.24e-33 14744 147535 all phecode
565.1 Anal and rectal polyp Digestive 1.14 1.11 – 1.16 1.93e-25 7351 73533 all phecode
567 Peritonitis and retroperitoneal infections Digestive 1.12 1.05 – 1.2 0.00116 929 9293 all phecode
568 Other disorders of peritoneum Digestive 1.11 1.07 – 1.15 6.8e-09 3262 32602 all phecode
568.1
Peritoneal adhesions (postoperative)
Peritoneal adhesions (postoperative) (postinfection)
 Digestive 1.11 1.07 – 1.15 4.98e-08 3101 30987 all phecode
569 Other disorders of intestine Digestive 1.1 1.07 – 1.14 4.33e-09 4192 41922 all phecode
569.1 Toxic gastroenteritis and colitis Digestive 1.09 0.919 – 1.29 0.322 148 1479 all phecode
569.2 Gastrointestinal complications Digestive 1.12 1.02 – 1.22 0.0214 486 4868 all phecode
571 Chronic liver disease and cirrhosis Digestive 1.19 1.15 – 1.24 1.59e-19 2957 29628 all phecode
571.5 Other chronic nonalcoholic liver disease Digestive 1.21 1.15 – 1.27 5.67e-14 1689 16917 all phecode
571.51 Cirrhosis of liver without mention of alcohol Digestive 1.2 0.987 – 1.46 0.0667 113 1139 all phecode
571.6 Primary biliary cirrhosis Digestive 1.27 1.12 – 1.45 0.000196 257 2568 all phecode
571.8
Liver abscess and sequelae of chronic liver
Liver abscess and sequelae of chronic liver disease
 Digestive 1.15 1.08 – 1.23 3.17e-05 976 9804 all phecode
571.81 Portal hypertension Digestive 1.18 1.08 – 1.28 0.000349 528 5285 all phecode
572 Ascites (non malignant) Digestive 1.05 0.998 – 1.11 0.0569 1544 15454 all phecode
573 Other disorders of liver Digestive 1.09 1.03 – 1.14 0.00257 1496 14982 all phecode
573.2 Liver replaced by transplant Digestive 1.09 0.886 – 1.33 0.429 96 960 all phecode
573.3 Hepatomegaly Digestive 1.27 1.12 – 1.43 0.000137 297 2968 all phecode
573.5 Jaundice (not of newborn) Digestive 1.08 1.01 – 1.16 0.025 896 8955 all phecode
573.7 Abnormal results of function study of liver Digestive 1.06 1.03 – 1.1 0.000488 3454 34597 all phecode
573.9 Abnormal serum enzyme levels Digestive 1.18 1.02 – 1.37 0.0248 209 2089 all phecode
574 Cholelithiasis and cholecystitis Digestive 1.09 1.08 – 1.11 1.97e-26 15607 156123 all phecode
574.1 Cholelithiasis Digestive 1.09 1.07 – 1.1 1.15e-19 13549 135537 all phecode
574.11 Cholelithiasis with acute cholecystitis Digestive 1.1 1.04 – 1.16 0.000683 1506 15072 all phecode
574.12 Cholelithiasis with other cholecystitis Digestive 1.07 1.04 – 1.1 6.86e-07 5429 54289 all phecode
574.2 Calculus of bile duct Digestive 1.1 1.06 – 1.15 1.26e-06 2620 26191 all phecode
574.3 Cholecystitis without cholelithiasis Digestive 1.13 1.09 – 1.18 5.08e-10 2748 27523 all phecode
575 Other biliary tract disease Digestive 1.1 1.07 – 1.14 1.22e-08 3867 38724 all phecode
575.1 Cholangitis Digestive 1.1 1 – 1.21 0.0429 495 4945 all phecode
575.2 Obstruction of bile duct Digestive 1.13 1.05 – 1.22 0.00126 774 7756 all phecode
575.6 Cholesterolosis of gallbladder Digestive 1.05 0.956 – 1.16 0.288 458 4577 all phecode
575.7 Other disorders of gallbladder Digestive 1.09 1.04 – 1.16 0.0015 1408 14107 all phecode
575.8 Other disorders of biliary tract Digestive 1.14 1.07 – 1.22 3.14e-05 1036 10367 all phecode
575.9
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of biliary tract
 Digestive 1.13 1.01 – 1.26 0.0316 348 3488 all phecode
577 Diseases of pancreas Digestive 1.09 1.05 – 1.14 1.83e-05 2668 26677 all phecode
577.1 Acute pancreatitis Digestive 1.1 1.05 – 1.15 5.04e-05 1996 19962 all phecode
577.2 Chronic pancreatitis Digestive 1.21 1.1 – 1.32 4.05e-05 515 5149 all phecode
577.3 Cyst and pseudocyst of pancreas Digestive 1.13 1.01 – 1.26 0.0329 365 3650 all phecode
578 Gastrointestinal hemorrhage Digestive 1.08 1.06 – 1.09 2.76e-25 20626 206278 all phecode
578.1 Hematemesis Digestive 1.18 1.13 – 1.24 8.89e-13 1958 19564 all phecode
578.2 Blood in stool Digestive 1.08 1.04 – 1.12 0.000247 2626 26283 all phecode
578.8 Hemorrhage of rectum and anus Digestive 1.08 1.06 – 1.1 5.92e-16 13073 130745 all phecode
578.9 Hemorrhage of gastrointestinal tract Digestive 1.08 1.05 – 1.11 3.92e-07 5275 52787 all phecode
579 Other symptoms involving abdomen and pelvis Digestive 1.06 1.01 – 1.12 0.0186 1548 15498 all phecode
579.2 Splenomegaly Digestive 1.11 1.01 – 1.23 0.0346 422 4246 all phecode
579.8 Nonspecific abnormal findings in stool contents Digestive 1.07 1.02 – 1.12 0.0113 1654 16540 all phecode
580 Nephritis; nephrosis; renal sclerosis Genitourinary 1.09 1.03 – 1.15 0.00184 1531 15350 all phecode
580.1 Glomerulonephritis Genitourinary 1.11 1.04 – 1.18 0.000977 1052 10544 all phecode
580.11 Proliferative glomerulonephritis Genitourinary 1.06 0.833 – 1.35 0.639 74 738 all phecode
580.12 Non-proliferative glomerulonephritis Genitourinary 1.02 0.849 – 1.22 0.843 135 1360 all phecode
580.14 Chronic glomerulonephritis, NOS Genitourinary 1.12 1.05 – 1.2 0.00109 876 8769 all phecode
580.2
Nephrotic syndrome without mention of
Nephrotic syndrome without mention of glomerulonephritis
 Genitourinary 1.03 0.933 – 1.13 0.597 468 4697 all phecode
580.3
Nephritis and nephropathy without mention of
Nephritis and nephropathy without mention of glomerulonephritis
 Genitourinary 1.05 0.923 – 1.2 0.454 246 2460 all phecode
580.32
Nephritis and nephropathy with pathological
Nephritis and nephropathy with pathological lesion
 Genitourinary 1.03 0.908 – 1.18 0.616 253 2529 all phecode
585 Renal failure Genitourinary 1.11 1.08 – 1.14 2.72e-16 6967 69751 all phecode
585.1 Acute renal failure Genitourinary 1.11 1.08 – 1.15 5.12e-12 4527 45305 all phecode
585.2 Renal failure NOS Genitourinary 1.13 1.07 – 1.19 1.01e-05 1460 14625 all phecode
585.3 Chronic renal failure [CKD] Genitourinary 1.12 1.07 – 1.16 8.05e-08 2644 26484 all phecode
585.31 Renal dialysis Genitourinary 1.14 1.04 – 1.26 0.00438 496 4955 all phecode
586 Other disorders of the kidney and ureters Genitourinary 1.11 1.07 – 1.15 1.48e-08 3355 33580 all phecode
586.1 Anatomical abnormatilies of kidney and ureters Genitourinary 1.18 1.02 – 1.35 0.0219 208 2089 all phecode
586.11 Small kidney Genitourinary 1.12 0.963 – 1.3 0.142 179 1799 all phecode
586.2 Cyst of kidney, acquired Genitourinary 1.09 1.02 – 1.15 0.00519 1257 12582 all phecode
586.3 Vascular disorders of kidney/hypertrophy Genitourinary 1.11 0.891 – 1.4 0.343 80 799 all phecode
586.4 Stricture/obstruction of ureter Genitourinary 1.14 1.07 – 1.22 0.000153 910 9122 all phecode
587 Kidney replaced by transpant Genitourinary 1.06 0.953 – 1.19 0.275 368 3683 all phecode
588 Disorders resulting from impaired renal function Genitourinary 1.01 0.823 – 1.24 0.915 99 990 all phecode
589 Abnormal results of function study of kidney Genitourinary 1.1 0.907 – 1.33 0.343 116 1158 all phecode
590 Pyelonephritis Genitourinary 1.18 1.12 – 1.25 9.56e-09 1328 13285 all phecode
591 Urinary tract infection Genitourinary 1.1 1.08 – 1.12 7.79e-23 12400 123937 all phecode
592 Cystitis and urethritis Genitourinary 1.04 1 – 1.08 0.0395 2966 29661 all phecode
592.1 Cystitis Genitourinary 1.04 1 – 1.08 0.0313 2904 29035 all phecode
592.11 Acute cystitis Genitourinary 1.12 0.938 – 1.33 0.215 138 1372 all phecode
592.12 Chronic cystitis Genitourinary 1.07 1 – 1.15 0.0438 889 8890 all phecode
592.13 Chronic interstitial cystitis Genitourinary 0.908 0.797 – 1.03 0.146 249 2486 all phecode
592.2 Urethritis and urethral syndrome Genitourinary 0.962 0.823 – 1.12 0.623 165 1662 all phecode
593 Hematuria Genitourinary 1.06 1.04 – 1.08 4.93e-13 16068 160204 all phecode
594 Urinary calculus Genitourinary 1.07 1.04 – 1.1 2.6e-07 6376 63761 all phecode
594.1 Calculus of kidney Genitourinary 1.09 1.05 – 1.13 2.07e-06 3175 31757 all phecode
594.2 Calculus of lower urinary tract Genitourinary 1 0.93 – 1.08 0.991 776 7764 all phecode
594.3 Calculus of ureter Genitourinary 1.09 1.04 – 1.13 9.89e-05 2401 24024 all phecode
594.8 Renal colic Genitourinary 1.08 1.03 – 1.13 0.00109 2050 20500 all phecode
595 Hydronephrosis Genitourinary 1.06 1.02 – 1.12 0.00836 1936 19395 all phecode
596 Other disorders of bladder Genitourinary 1.04 1.01 – 1.06 0.000838 9771 97778 all phecode
596.1 Bladder neck obstruction Genitourinary 1.01 0.968 – 1.06 0.54 1969 19690 all phecode
596.5 Functional disorders of bladder Genitourinary 1.11 1.05 – 1.16 0.000106 1658 16572 all phecode
597 Other disorders of urethra and urinary tract Genitourinary 1.08 1.04 – 1.11 6.59e-06 3913 39135 all phecode
597.1 Urethral stricture (not specified as infectious) Genitourinary 1.09 1.05 – 1.13 3.38e-06 3317 33137 all phecode
597.2 Urinary complications NEC Genitourinary 1.05 0.827 – 1.32 0.71 78 778 all phecode
598 Abnormal findings on examination of urine Genitourinary 1.08 1.05 – 1.12 4.69e-06 3528 35302 all phecode
598.9
Other nonspecific findings on examination of
Other nonspecific findings on examination of urine
 Genitourinary 1.06 0.939 – 1.19 0.36 304 3035 all phecode
599 Other symptoms/disorders or the urinary system Genitourinary 1.09 1.08 – 1.11 1.5e-30 18428 184311 all phecode
599.1 Urinary obstruction Genitourinary 1.12 0.952 – 1.31 0.176 166 1670 all phecode
599.2 Retention of urine Genitourinary 1.04 1.01 – 1.07 0.00242 6718 67168 all phecode
599.3 Dysuria Genitourinary 1.1 1.04 – 1.17 0.00183 1196 11967 all phecode
599.4 Urinary incontinence Genitourinary 1.12 1.1 – 1.15 9.06e-24 8748 87477 all phecode
599.5 Frequency of urination and polyuria Genitourinary 1.07 1.03 – 1.1 7.64e-05 4018 40144 all phecode
599.6 Oliguria and anuria Genitourinary 1.15 0.94 – 1.4 0.177 105 1059 all phecode
599.8 Other symptoms involving urinary system Genitourinary 1.19 0.921 – 1.54 0.182 62 620 all phecode
599.9 Other abnormality of urination Genitourinary 1.1 1.05 – 1.16 5e-05 1913 19151 all phecode
600 Hyperplasia of prostate Genitourinary 1.02 1 – 1.04 0.0271 11093 87892 all phecode
601 Inflammatory diseases of prostate Genitourinary 0.986 0.942 – 1.03 0.533 2081 20818 all phecode
601.1 Prostatitis Genitourinary 0.976 0.927 – 1.03 0.37 1563 15644 all phecode
601.11 Acute prostatitis Genitourinary 0.922 0.806 – 1.05 0.234 234 2358 all phecode
601.12 Chronic prostatitis Genitourinary 1 0.939 – 1.07 0.9 910 9089 all phecode
601.3 Orchitis and epididymitis Genitourinary 1.4 1.07 – 1.82 0.0125 59 588 all phecode
601.4 Balanoposthitis Genitourinary 1.01 0.896 – 1.14 0.852 287 2864 all phecode
601.8
Other inflammatory disorders of male genital
Other inflammatory disorders of male genital organs
 Genitourinary 1.03 0.917 – 1.16 0.598 303 3019 all phecode
602 Other disorders of prostate Genitourinary 1.07 1.01 – 1.13 0.0222 1341 13408 all phecode
603 Other disorders of testis Genitourinary 1.05 1.01 – 1.1 0.019 2150 21512 all phecode
603.1 Hydrocele Genitourinary 1.04 0.988 – 1.11 0.123 1339 13402 all phecode
604 Disorders of penis Genitourinary 1.06 1.03 – 1.1 0.000805 3280 32779 all phecode
604.1 Redundant prepuce and phimosis/BXO Genitourinary 1.08 1.04 – 1.12 0.000132 2719 27172 all phecode
605 Erectile dysfunction [ED] Genitourinary 1.13 0.999 – 1.28 0.0515 278 2800 all phecode
608 Other disorders of male genital organs Genitourinary 1.05 1.01 – 1.09 0.0089 2822 28236 all phecode
609 Male infertility and abnormal spermatozoa Genitourinary 1.2 1.04 – 1.38 0.00991 214 2138 all phecode
609.1 Infertility, male Genitourinary 1.05 0.818 – 1.35 0.699 63 638 all phecode
609.2 Abnormal spermatozoa Genitourinary 1.22 1.05 – 1.43 0.0117 169 1698 all phecode
610 Benign mammary dysplasias Genitourinary 1.06 1.02 – 1.1 0.00605 2482 24809 all phecode
610.1 Cystic mastopathy Genitourinary 1 0.934 – 1.07 1 925 9250 all phecode
610.2 Fibroadenosis of breast Genitourinary 1.08 0.963 – 1.22 0.183 306 3057 all phecode
610.3 Fibrosclerosis of breast Genitourinary 1.07 0.952 – 1.21 0.245 302 3018 all phecode
610.4 Benign neoplasm of breast Genitourinary 1.04 0.986 – 1.1 0.149 1388 13865 all phecode
610.8 Other specified benign mammary dysplasias Genitourinary 1 0.929 – 1.09 0.901 696 6954 all phecode
611 Abnormal findings on mammogram or breast exam Genitourinary 1.03 0.982 – 1.09 0.201 1574 15731 all phecode
611.1 Abnormal mammogram Genitourinary 1.15 0.876 – 1.5 0.319 57 569 all phecode
611.3 Lump or mass in breast Genitourinary 1.03 0.979 – 1.09 0.239 1522 15213 all phecode
612
Breast conditions, congenital or relating to
Breast conditions, congenital or relating to hormones
 Genitourinary 1.17 1.09 – 1.26 7.67e-06 887 8871 all phecode
612.2 Hypertrophy of breast (Gynecomastia) Genitourinary 1.18 1.1 – 1.26 8.77e-06 849 8490 all phecode
612.3 Congenital anomalies of breast Genitourinary 1.13 0.903 – 1.42 0.28 72 719 all phecode
613 Other nonmalignant breast conditions Genitourinary 1.05 1 – 1.11 0.038 1651 16519 all phecode
613.1 Inflammatory disease of breast Genitourinary 1.04 0.966 – 1.13 0.277 720 7210 all phecode
613.5 Mastodynia Genitourinary 1.05 0.836 – 1.32 0.669 77 768 all phecode
613.7 Other signs and symptoms in breast Genitourinary 1.04 0.959 – 1.12 0.373 702 7013 all phecode
613.8 Other specified disorders of breast Genitourinary 1.1 0.978 – 1.23 0.115 327 3278 all phecode
613.9 Breast disorder NOS Genitourinary 0.906 0.786 – 1.04 0.171 207 2069 all phecode
614 Inflammatory diseases of female pelvic organs Genitourinary 1.09 1.06 – 1.12 6.65e-10 5711 57118 all phecode
614.1
Pelvic peritoneal adhesions, female
Pelvic peritoneal adhesions, female (postoperative) (postinfection)
 Genitourinary 1.08 1.04 – 1.12 0.000322 2538 25363 all phecode
614.3 Pelvic inflammatory disease (PID) Genitourinary 1.13 1.05 – 1.21 0.00102 830 8308 all phecode
614.31 Acute inflammatory pelvic disease Genitourinary 0.994 0.76 – 1.3 0.967 61 608 all phecode
614.32 Chronic inflammatory pelvic disease Genitourinary 1.11 1 – 1.22 0.0475 422 4221 all phecode
614.33 Pelvic inflammatory disease, NOS Genitourinary 1.11 0.991 – 1.24 0.0713 351 3510 all phecode
614.4 Inflammatory diseases of uterus, except cervix Genitourinary 1.04 0.917 – 1.18 0.547 277 2775 all phecode
614.5
Inflammatory disease of cervix, vagina, and
Inflammatory disease of cervix, vagina, and vulva
 Genitourinary 1.1 1.06 – 1.15 4.18e-06 2601 26023 all phecode
614.51 Cervicitis and endocervicitis Genitourinary 1.06 0.998 – 1.12 0.0604 1318 13189 all phecode
614.52 Vaginitis and vulvovaginitis Genitourinary 1.14 1.03 – 1.26 0.00983 428 4273 all phecode
614.53 Cyst or abscess of Bartholin's gland Genitourinary 1.12 1.04 – 1.2 0.00418 755 7574 all phecode
614.54 Abscess or ulceration of vulva Genitourinary 1.2 1.06 – 1.36 0.00385 274 2737 all phecode
615 Endometriosis Genitourinary 1.06 1.03 – 1.1 0.000196 4029 40284 all phecode
617
Disorders secondary to childbirth, surgery
Disorders secondary to childbirth, surgery, trauma
 Genitourinary 1.02 0.907 – 1.15 0.718 304 3037 all phecode
618 Genital prolapse Genitourinary 1.04 1.02 – 1.06 6.33e-05 11689 116878 all phecode
618.1 Prolapse of vaginal walls Genitourinary 1.07 1.04 – 1.09 9.83e-08 7392 73940 all phecode
618.2 Uterine/Uterovaginal prolapse Genitourinary 1 0.974 – 1.03 0.877 5393 53918 all phecode
618.5 Prolapse of vaginal vault after hysterectomy Genitourinary 1.14 1.04 – 1.25 0.00366 512 5125 all phecode
618.6 Vaginal enterocele, congenital or acquired Genitourinary 1.11 1.03 – 1.21 0.00902 680 6794 all phecode
619 Noninflammatory female genital disorders Genitourinary 1.04 1.02 – 1.06 0.000626 8726 87297 all phecode
619.1
Noninflammatory disorders of ovary, fallopian
Noninflammatory disorders of ovary, fallopian tube, and broad ligament
 Genitourinary 1.05 0.976 – 1.14 0.178 729 7284 all phecode
619.2 Disorders of uterus, NEC Genitourinary 1 0.967 – 1.04 0.906 3324 33273 all phecode
619.3 Noninflammatory disorders of cervix Genitourinary 1.04 0.996 – 1.08 0.0785 2860 28608 all phecode
619.4 Noninflammatory disorders of vagina Genitourinary 1.06 1.01 – 1.12 0.0139 1768 17669 all phecode
619.5 Noninflammatory disorders of vulva and perineum Genitourinary 1.07 1.01 – 1.13 0.0214 1350 13489 all phecode
620 Dysplasia of female genital organs Genitourinary 1.12 0.881 – 1.43 0.352 72 720 all phecode
621 Endometrial hyperplasia Genitourinary 1.02 0.957 – 1.08 0.582 1129 11294 all phecode
622 Polyp of female genital organs Genitourinary 0.993 0.973 – 1.01 0.522 10480 104803 all phecode
622.1 Polyp of corpus uteri Genitourinary 0.997 0.974 – 1.02 0.804 7857 78601 all phecode
622.2 Mucous polyp of cervix Genitourinary 0.986 0.952 – 1.02 0.441 3442 34387 all phecode
623 Hypertrophy of female genital organs Genitourinary 1.06 1 – 1.12 0.045 1268 12684 all phecode
624 Symptoms involving female genital tract Genitourinary 1.03 0.963 – 1.11 0.353 797 7961 all phecode
624.1 Dystrophy of female genital tract Genitourinary 1.08 0.947 – 1.23 0.256 237 2365 all phecode
624.2 Atrophy of female genital tract Genitourinary 1.02 0.924 – 1.12 0.701 440 4398 all phecode
624.9 stress incontinence, female Genitourinary 1.12 1.09 – 1.15 9.75e-16 5865 58634 all phecode
625
Pain and other symptoms associated with female
Pain and other symptoms associated with female genital organs
 Genitourinary 1.06 1.02 – 1.1 0.00225 2876 28740 all phecode
625.1 Dyspareunia Genitourinary 1.05 0.985 – 1.11 0.142 1188 11891 all phecode
626
Disorders of menstruation and other abnormal
Disorders of menstruation and other abnormal bleeding from female genital tract
 Genitourinary 1.07 1.05 – 1.09 5.44e-15 16168 115018 all phecode
626.1 Irregular menstrual cycle/bleeding Genitourinary 1.07 1.06 – 1.09 2.34e-15 14110 109918 all phecode
626.11 Absent or infrequent menstruation Genitourinary 1.32 1.09 – 1.6 0.0047 109 1099 all phecode
626.12 Excessive or frequent menstruation Genitourinary 1.07 1.05 – 1.1 7.02e-11 9727 91749 all phecode
626.13 Irregular menstrual cycle Genitourinary 1.07 1.02 – 1.12 0.00484 1985 19829 all phecode
626.14 Irregular menstrual bleeding Genitourinary 1.07 1.04 – 1.11 6.99e-05 3804 38021 all phecode
626.2 Dysmenorrhea Genitourinary 1.18 1.13 – 1.24 1.64e-11 1778 17767 all phecode
626.4 Premenstrual tension syndromes Genitourinary 1.28 1.08 – 1.52 0.00365 159 1587 all phecode
626.8 Infertility, female Genitourinary 1.02 0.967 – 1.08 0.434 1362 13613 all phecode
627 Menopausal and postmenopausal disorders Genitourinary 1.02 1 – 1.04 0.0498 10392 103948 all phecode
627.1 Postmenopausal bleeding Genitourinary 1.01 0.989 – 1.03 0.325 9042 90439 all phecode
627.2 Symptomatic menopause Genitourinary 1.2 1.04 – 1.4 0.0151 183 1826 all phecode
627.3 Postmenopausal atrophic vaginitis Genitourinary 0.988 0.929 – 1.05 0.715 1111 11115 all phecode
627.4 Premenopausal menorrhagia Genitourinary 0.984 0.873 – 1.11 0.799 310 3097 all phecode
628 Ovarian cyst Genitourinary 1.11 1.07 – 1.14 3.29e-11 4747 47482 all phecode
634 Miscarriage; stillbirth Pregnancy Complications 1.01 0.977 – 1.04 0.699 5218 36422 all phecode
634.1 Missed abortion/Hydatidiform mole Pregnancy Complications 0.943 0.887 – 1 0.0651 1136 11300 all phecode
634.3 Ectopic pregnancy Pregnancy Complications 1 0.892 – 1.12 0.994 331 3305 all phecode
635
Hemorrhage during pregnancy; childbirth and
Hemorrhage during pregnancy; childbirth and postpartum
 Pregnancy Complications 0.943 0.9 – 0.988 0.0131 1974 17372 all phecode
635.2
Antepartum hemorrhage, abruptio placentae, and
Antepartum hemorrhage, abruptio placentae, and placenta previa
 Pregnancy Complications 0.925 0.862 – 0.993 0.0314 866 8614 all phecode
635.3 Placenta previa and abruptio placenta Pregnancy Complications 0.93 0.877 – 0.985 0.0135 1270 12306 all phecode
636
Early or threatened labor; hemorrhage in early
Early or threatened labor; hemorrhage in early pregnancy
 Pregnancy Complications 1.01 0.964 – 1.05 0.786 2347 19972 all phecode
636.2 Early onset of delivery Pregnancy Complications 0.96 0.883 – 1.04 0.342 617 6144 all phecode
636.3 Hemorrhage in early pregnancy Pregnancy Complications 1.03 0.968 – 1.1 0.351 1082 10766 all phecode
638 Other high-risk pregnancy Pregnancy Complications 0.977 0.761 – 1.26 0.858 70 700 all phecode
642
Hypertension complicating pregnancy
Hypertension complicating pregnancy, childbirth, and the puerperium
 Pregnancy Complications 0.923 0.867 – 0.982 0.0112 1110 11074 all phecode
642.1 Preeclampsia and eclampsia Pregnancy Complications 0.946 0.839 – 1.07 0.359 307 3058 all phecode
643 Excessive vomiting in pregnancy Pregnancy Complications 1 0.866 – 1.16 0.99 215 2149 all phecode
643.1 Hyperemesis gravidarum Pregnancy Complications 0.89 0.752 – 1.05 0.176 153 1525 all phecode
645 Late pregnancy and failed induction Pregnancy Complications 0.967 0.912 – 1.03 0.267 1250 12450 all phecode
646 Other complications of pregnancy NEC Pregnancy Complications 0.974 0.932 – 1.02 0.244 2228 20847 all phecode
647
Infectious and parasitic complications
Infectious and parasitic complications affecting pregnancy
 Pregnancy Complications 0.899 0.703 – 1.15 0.395 68 679 all phecode
647.1
Infections of genitourinary tract during
Infections of genitourinary tract during pregnancy
 Pregnancy Complications 0.997 0.882 – 1.13 0.965 275 2748 all phecode
649
Other conditions or status of the mother
Other conditions or status of the mother complicating pregnancy, childbirth, or the puerperium
 Pregnancy Complications 0.996 0.814 – 1.22 0.967 113 1129 all phecode
649.1
Diabetes or abnormal glucose tolerance
Diabetes or abnormal glucose tolerance complicating pregnancy
 Pregnancy Complications 1.03 0.886 – 1.19 0.711 193 1922 all phecode
650 Normal delivery Pregnancy Complications 0.958 0.914 – 1 0.0709 1922 18973 all phecode
651 Multiple gestation Pregnancy Complications 0.978 0.877 – 1.09 0.696 346 3454 all phecode
652
Malposition and malpresentation of fetus or
Malposition and malpresentation of fetus or obstruction
 Pregnancy Complications 0.953 0.907 – 1 0.0595 1716 16521 all phecode
653
Problems associated with amniotic cavity and
Problems associated with amniotic cavity and membranes
 Pregnancy Complications 0.894 0.846 – 0.945 7.12e-05 1401 13649 all phecode
654
Other and unspecified complications of birth
Other and unspecified complications of birth; puerperium affecting management of mother
 Pregnancy Complications 1.05 0.835 – 1.32 0.679 74 739 all phecode
655
Known or suspected fetal abnormality affecting
Known or suspected fetal abnormality affecting management of mother
 Pregnancy Complications 0.938 0.908 – 0.969 0.000105 4306 29454 all phecode
656 Other perinatal conditions of fetus or newborn Pregnancy Complications 1 0.821 – 1.22 0.996 109 1080 all phecode
661 Fetal distress and abnormal forces of labor Pregnancy Complications 0.913 0.874 – 0.954 4.97e-05 2265 18397 all phecode
663
Umbilical cord complications during labor and
Umbilical cord complications during labor and delivery
 Pregnancy Complications 0.911 0.834 – 0.996 0.0401 532 5316 all phecode
665 Obstetrical/birth trauma Pregnancy Complications 0.929 0.901 – 0.957 1.33e-06 5313 29472 all phecode
669 Complications of labor and delivery NEC Pregnancy Complications 0.903 0.867 – 0.941 1.38e-06 2552 21174 all phecode
671
Venous/cerebrovascular complications embolism
Venous/cerebrovascular complications embolism in pregnancy and the puerperium
 Pregnancy Complications 1.06 0.9 – 1.25 0.493 164 1628 all phecode
674 Other complications of the puerperium NEC Pregnancy Complications 0.883 0.776 – 1.01 0.0598 262 2605 all phecode
676
Other disorders of the breast associated with
Other disorders of the breast associated with childbirth and disorders of lactation
 Pregnancy Complications 1.17 0.918 – 1.49 0.205 63 624 all phecode
679 Complications of in utero procedures Dermatologic 0.896 0.678 – 1.18 0.438 53 530 all phecode
681 Superficial cellulitis and abscess Dermatologic 1.08 1.06 – 1.11 1.25e-10 7200 72225 all phecode
681.1 Cellulitis and abscess of fingers/toes Dermatologic 0.991 0.909 – 1.08 0.839 563 5647 all phecode
681.2 Cellulitis and abscess of face/neck Dermatologic 1.13 1.03 – 1.24 0.00829 520 5208 all phecode
681.3 Cellulitis and abscess of arm/hand Dermatologic 1.09 1.06 – 1.12 1.98e-09 5481 55014 all phecode
681.5 Cellulitis and abscess of leg, except foot Dermatologic 1.09 1.06 – 1.12 1.27e-09 5487 55074 all phecode
681.6 Cellulitis and abscess of foot, toe Dermatologic 1.09 1.06 – 1.12 3.72e-09 5444 54643 all phecode
681.7 Cellulitis and abscess of trunk Dermatologic 1.15 1.06 – 1.26 0.00102 597 5987 all phecode
686
Other local infections of skin and subcutaneous
Other local infections of skin and subcutaneous tissue
 Dermatologic 1.09 1.03 – 1.16 0.00174 1337 13427 all phecode
686.1 Carbuncle and furuncle Dermatologic 1.16 1.11 – 1.21 5.58e-12 2284 22925 all phecode
686.3 Pilonidal cyst Dermatologic 1.29 1.19 – 1.41 3.98e-09 583 5837 all phecode
686.4 Pyogenic granuloma Dermatologic 0.975 0.875 – 1.09 0.643 362 3615 all phecode
687 Symptoms affecting skin Dermatologic 1.04 0.95 – 1.13 0.427 548 5508 all phecode
687.1 Rash and other nonspecific skin eruption Dermatologic 1.06 1.01 – 1.11 0.00984 2146 21470 all phecode
687.2 Localized superficial swelling, mass, or lump Dermatologic 1.05 0.931 – 1.19 0.426 283 2839 all phecode
687.3 Changes in skin texture Dermatologic 1.05 0.865 – 1.28 0.613 106 1070 all phecode
687.4 Disturbance of skin sensation Dermatologic 1.1 1.06 – 1.14 7.99e-07 2884 28859 all phecode
689 Disorder of skin and subcutaneous tissue NOS Dermatologic 1.05 1.02 – 1.08 0.000225 5747 57521 all phecode
690 Erythematosquamous dermatosis Dermatologic 1.03 0.816 – 1.3 0.796 71 710 all phecode
690.1 Seborrheic dermatitis Dermatologic 0.997 0.754 – 1.32 0.984 53 530 all phecode
691 Congenital anomalies of skin Dermatologic 1.09 0.905 – 1.31 0.37 120 1199 all phecode
694 Dyschromia and Vitiligo Dermatologic 1.04 0.975 – 1.11 0.234 986 9854 all phecode
694.1 Vitiligo Dermatologic 1.04 0.799 – 1.35 0.783 60 599 all phecode
694.2 Other dyschromia Dermatologic 1.05 0.975 – 1.13 0.204 782 7821 all phecode
694.3 Vascular disorders of skin Dermatologic 1.01 0.832 – 1.22 0.923 117 1170 all phecode
695 Erythematous conditions Dermatologic 1.06 1.02 – 1.11 0.00473 2379 23813 all phecode
695.1 Toxic erythema Dermatologic 1.2 0.984 – 1.46 0.0726 109 1090 all phecode
695.2 Bullous dermatoses Dermatologic 0.986 0.824 – 1.18 0.875 137 1365 all phecode
695.21 Dermatitis herpetiformis Dermatologic 0.775 0.58 – 1.03 0.0835 57 569 all phecode
695.22 Pemphigus and pemphigoid Dermatologic 1.01 0.792 – 1.29 0.93 73 727 all phecode
695.3 Rosacea Dermatologic 1.13 1.01 – 1.27 0.0351 309 3097 all phecode
695.4 Lupus (localized and systemic) Dermatologic 1.01 0.915 – 1.12 0.825 411 4114 all phecode
695.41 Cutaneous lupus erythematosus Dermatologic 1.02 0.855 – 1.23 0.793 130 1295 all phecode
695.42 Systemic lupus erythematosus Dermatologic 0.985 0.882 – 1.1 0.791 340 3407 all phecode
695.7 Prurigo and Lichen Dermatologic 1.02 0.946 – 1.1 0.628 775 7760 all phecode
695.8 Other specified erythematous conditions Dermatologic 1.18 1.03 – 1.35 0.015 236 2359 all phecode
695.81 Erythema nodosum Dermatologic 1.08 0.849 – 1.37 0.538 76 760 all phecode
695.9 Unspecified erythematous condition Dermatologic 1.06 0.965 – 1.16 0.227 467 4672 all phecode
696 Psoriasis and related disorders Dermatologic 1.14 1.1 – 1.19 9.47e-10 2252 22509 all phecode
696.4 Psoriasis Dermatologic 1.14 1.09 – 1.19 2.25e-09 2198 21969 all phecode
696.41 Psoriasis vulgaris Dermatologic 1.19 1.13 – 1.25 8.43e-12 1680 16796 all phecode
696.42 Psoriatic arthropathy Dermatologic 1.07 0.995 – 1.16 0.0659 706 7052 all phecode
697 Sarcoidosis Dermatologic 0.922 0.844 – 1.01 0.0687 539 5373 all phecode
698 Pruritus and related conditions Dermatologic 1.12 1.04 – 1.2 0.0035 782 7814 all phecode
700 Corns and callosities Dermatologic 1.29 1.14 – 1.45 6.48e-05 291 2904 all phecode
701
Other hypertrophic and atrophic conditions of
Other hypertrophic and atrophic conditions of skin
 Dermatologic 1.08 1.05 – 1.12 1.57e-07 4663 46650 all phecode
701.1 Keratoderma, acquired Dermatologic 1.16 0.932 – 1.44 0.183 87 870 all phecode
701.2 Scar conditions and fibrosis of skin Dermatologic 1.09 1.04 – 1.13 0.000143 2348 23478 all phecode
701.3 Circumscribed scleroderma Dermatologic 1.09 0.842 – 1.41 0.512 61 610 all phecode
701.4 Keloid scar Dermatologic 1.19 1.03 – 1.36 0.0154 216 2159 all phecode
701.5 Abnormal granulation tissue Dermatologic 1.02 0.922 – 1.12 0.762 455 4568 all phecode
701.6 Acquired acanthosis nigricans Dermatologic 1.08 0.884 – 1.33 0.44 102 1019 all phecode
702
Degenerative skin conditions and other
Degenerative skin conditions and other dermatoses
 Dermatologic 1.01 0.987 – 1.04 0.314 5459 54587 all phecode
702.1 Actinic keratosis Dermatologic 1.03 0.987 – 1.07 0.187 2585 25842 all phecode
702.2 Seborrheic keratosis Dermatologic 1.01 0.974 – 1.05 0.584 3078 30772 all phecode
703 Diseases of nail, NOS Dermatologic 1.06 0.953 – 1.18 0.279 354 3539 all phecode
703.1 Ingrowing nail Dermatologic 1.03 0.965 – 1.1 0.373 966 9660 all phecode
704 Diseases of hair and hair follicles Dermatologic 1.08 1.05 – 1.11 4.59e-07 5267 52727 all phecode
704.1 Alopecia Dermatologic 1.01 0.845 – 1.21 0.907 125 1269 all phecode
704.8
Other specified diseases of hair and hair
Other specified diseases of hair and hair follicles
 Dermatologic 1.08 0.853 – 1.37 0.517 76 759 all phecode
705 Disorders of sweat glands Dermatologic 1.49 1.3 – 1.71 1.63e-08 228 2287 all phecode
705.3 Hidradenitis Dermatologic 1.6 1.37 – 1.87 3.63e-09 186 1868 all phecode
705.8 Hyperhidrosis Dermatologic 1.09 1 – 1.18 0.0482 591 5919 all phecode
706 Diseases of sebaceous glands Dermatologic 1.09 1.07 – 1.12 6.05e-15 8317 83195 all phecode
706.1 Acne Dermatologic 1.29 1.02 – 1.62 0.0323 78 779 all phecode
706.2 Sebaceous cyst Dermatologic 1.09 1.06 – 1.11 1.73e-13 8787 87882 all phecode
707 Chronic ulcer of skin Dermatologic 1.11 1.06 – 1.17 1e-05 1953 19654 all phecode
707.1 Decubitus ulcer Dermatologic 1.16 1.09 – 1.25 1.52e-05 909 9097 all phecode
709 Diffuse diseases of connective tissue Dermatologic 1.1 1.06 – 1.14 3.32e-07 3432 34317 all phecode
709.2 Sicca syndrome Dermatologic 1.06 0.966 – 1.16 0.222 508 5073 all phecode
709.3 Systemic sclerosis Dermatologic 1.02 0.87 – 1.19 0.828 176 1753 all phecode
709.6
Other specified diffuse diseases of connective
Other specified diffuse diseases of connective tissue
 Dermatologic 1.03 0.802 – 1.32 0.828 65 649 all phecode
709.7 Unspecified diffuse connective tissue disease Dermatologic 1.11 1.07 – 1.16 2.33e-07 2714 27144 all phecode
710
Osteomyelitis, periostitis, and other
Osteomyelitis, periostitis, and other infections involving bone
 Musculoskeletal 1.14 1.05 – 1.24 0.00231 602 6034 all phecode
710.1 Osteomyelitis Musculoskeletal 1.13 1.03 – 1.23 0.00652 556 5574 all phecode
710.12 Chronic osteomyelitis Musculoskeletal 1.12 0.969 – 1.3 0.123 194 1947 all phecode
710.19 Unspecified osteomyelitis Musculoskeletal 1.17 1.05 – 1.3 0.00342 398 3997 all phecode
711 Arthropathy associated with infections Musculoskeletal 1.07 0.964 – 1.18 0.213 421 4225 all phecode
711.1 Pyogenic arthritis Musculoskeletal 1.11 0.989 – 1.24 0.0777 328 3296 all phecode
712 Infective connective tissue disorders Musculoskeletal 1.31 1.05 – 1.63 0.0173 81 810 all phecode
713
Arthropathy associated with other disorders
Arthropathy associated with other disorders classified elsewhere
 Musculoskeletal 1.19 1.01 – 1.4 0.0373 148 1499 all phecode
713.5
Arthropathy associated with neurological
Arthropathy associated with neurological disorders
 Musculoskeletal 1.26 0.985 – 1.61 0.0655 65 669 all phecode
714
Rheumatoid arthritis and other inflammatory
Rheumatoid arthritis and other inflammatory polyarthropathies
 Musculoskeletal 1.2 1.16 – 1.23 7.2e-32 4832 48320 all phecode
714.1 Rheumatoid arthritis Musculoskeletal 1.2 1.16 – 1.24 4.06e-30 4372 43714 all phecode
715 Other inflammatory spondylopathies Musculoskeletal 1.16 1.1 – 1.22 2.01e-08 1659 16588 all phecode
715.1 Sacroiliitis NEC Musculoskeletal 1.19 0.983 – 1.44 0.0746 113 1129 all phecode
715.2 Ankylosing spondylitis Musculoskeletal 1.12 1.03 – 1.21 0.00973 618 6177 all phecode
716 Other arthropathies Musculoskeletal 1.14 1.13 – 1.15 2.31e-123 37478 265375 all phecode
716.1 Unspecified polyarthropathy or polyarthritis Musculoskeletal 1.19 1.15 – 1.23 8.36e-22 3505 35090 all phecode
716.2 Unspecified monoarthritis Musculoskeletal 1.12 1.11 – 1.14 1.97e-43 15522 155339 all phecode
716.9 Arthropathy NOS Musculoskeletal 1.14 1.13 – 1.15 5.47e-119 35944 262308 all phecode
717 Polymyalgia Rheumatica Musculoskeletal 1.07 1.01 – 1.14 0.0312 1145 11480 all phecode
720 Spinal stenosis Musculoskeletal 1.19 1.15 – 1.23 2.33e-23 3705 37091 all phecode
721 Spondylosis and allied disorders Musculoskeletal 1.18 1.15 – 1.21 4.82e-43 7832 78318 all phecode
721.1 Spondylosis without myelopathy Musculoskeletal 1.18 1.15 – 1.21 1.03e-28 5045 50451 all phecode
721.2 Spondylosis with myelopathy Musculoskeletal 1.24 1.07 – 1.43 0.00407 189 1899 all phecode
721.8 Other allied disorders of spine Musculoskeletal 1.07 0.96 – 1.2 0.217 352 3519 all phecode
722 Intervertebral disc disorders Musculoskeletal 1.18 1.16 – 1.21 1.32e-50 8978 89848 all phecode
722.1 Displacement of intervertebral disc Musculoskeletal 1.25 1.14 – 1.37 2e-06 512 5116 all phecode
722.6 Degeneration of intervertebral disc Musculoskeletal 1.2 1.15 – 1.25 3.21e-20 2831 28328 all phecode
722.8 Postlaminectomy syndrome Musculoskeletal 1.34 1.06 – 1.71 0.0153 67 669 all phecode
722.9 Other and unspecified disc disorder Musculoskeletal 1.16 1.12 – 1.19 3.81e-20 4407 44127 all phecode
723 Other disorders of cervical region Musculoskeletal 1.13 1.03 – 1.24 0.00726 517 5173 all phecode
723.1 Torticollis Musculoskeletal 1.03 0.846 – 1.25 0.782 107 1068 all phecode
724 Other and unspecified disorders of back Musculoskeletal 1.11 1.06 – 1.16 5.38e-06 2052 20514 all phecode
724.1 Disorders of sacrum Musculoskeletal 1.17 1.06 – 1.29 0.00248 403 4024 all phecode
724.2 Disorders of coccyx Musculoskeletal 1.17 1.06 – 1.3 0.00198 406 4054 all phecode
724.8 Other symptoms referable to back Musculoskeletal 1.19 0.925 – 1.52 0.178 63 630 all phecode
724.9 Other unspecified back disorders Musculoskeletal 1.09 1.04 – 1.15 0.000986 1614 16139 all phecode
726 Peripheral enthesopathies and allied syndromes Musculoskeletal 1.12 1.1 – 1.14 1.52e-38 14663 146691 all phecode
726.1 Enthesopathy Musculoskeletal 1.11 1.08 – 1.13 1.7e-20 9589 95900 all phecode
726.2 Synoviopathy Musculoskeletal 1.24 1.1 – 1.39 0.000248 334 3336 all phecode
726.3 Bursitis Musculoskeletal 1.17 1.09 – 1.25 1.41e-05 854 8573 all phecode
727 Other disorders of synovium, tendon, and bursa Musculoskeletal 1.11 1.09 – 1.14 2.14e-18 7331 73332 all phecode
727.1 Synovitis and tenosynovitis Musculoskeletal 1.12 1.08 – 1.17 7.81e-09 2737 27406 all phecode
727.2 Bursitis disorders Musculoskeletal 1.22 0.999 – 1.49 0.051 103 1029 all phecode
727.4 Ganglion and cyst of synovium, tendon, and bursa Musculoskeletal 1.1 1.06 – 1.14 9.16e-07 3109 31085 all phecode
727.5 Rupture of synovium Musculoskeletal 1.13 1.04 – 1.23 0.00574 586 5854 all phecode
727.6 Rupture of tendon, nontraumatic Musculoskeletal 1.09 0.975 – 1.22 0.131 353 3527 all phecode
727.7 Contracture of tendon (sheath) Musculoskeletal 1.07 0.899 – 1.27 0.443 143 1429 all phecode
728 Disorders of muscle, ligament, and fascia Musculoskeletal 1.06 1.03 – 1.1 0.000412 3677 36788 all phecode
728.2 Laxity of ligament or hypermobility syndrome Musculoskeletal 1.06 0.955 – 1.17 0.286 412 4115 all phecode
728.7 Fasciitis Musculoskeletal 1.06 1.02 – 1.09 0.000845 3803 38045 all phecode
728.71
Contracture of palmar fascia [Dupuytren's
Contracture of palmar fascia [Dupuytren's disease]
 Musculoskeletal 1.06 1.02 – 1.1 0.00108 3477 34788 all phecode
729 Other disorders of soft tissues Musculoskeletal 1.12 1.09 – 1.15 1.21e-16 6014 60309 all phecode
729.1 Rheumatism, unspecified and fibrositis Musculoskeletal 1.12 1.05 – 1.19 0.00101 1005 10063 all phecode
729.3 Panniculitis Musculoskeletal 1.15 0.942 – 1.4 0.172 101 1009 all phecode
731
Osteitis deformans and osteopathies associated
Osteitis deformans and osteopathies associated with other disorders classified elsewhere
 Musculoskeletal 1.09 0.962 – 1.23 0.175 276 2758 all phecode
731.1 Osteitis deformans [Paget's disease of bone] Musculoskeletal 1.09 0.963 – 1.24 0.168 261 2609 all phecode
732 Osteochondropathies Musculoskeletal 1.13 1.02 – 1.24 0.0154 467 4679 all phecode
732.1 Juvenile osteochondrosis Musculoskeletal 1.15 0.998 – 1.33 0.0537 207 2068 all phecode
732.7 Osteochondritis dissecans Musculoskeletal 1.11 0.852 – 1.45 0.44 57 570 all phecode
733 Other disorders of bone and cartilage Musculoskeletal 1.1 1.05 – 1.15 0.000173 1777 17814 all phecode
733.2 Cyst of bone Musculoskeletal 1.05 0.93 – 1.18 0.439 311 3115 all phecode
733.4 Aseptic necrosis of bone Musculoskeletal 1.11 1.02 – 1.22 0.0166 540 5393 all phecode
733.6 Costochondritis Musculoskeletal 1.13 0.945 – 1.35 0.181 128 1276 all phecode
733.8 Malunion and nonunion of fracture Musculoskeletal 1.11 1.04 – 1.17 0.00064 1231 12313 all phecode
733.9 Chondromalacia Musculoskeletal 1.22 1.01 – 1.46 0.0346 121 1206 all phecode
735 Acquired foot deformities Musculoskeletal 1.07 1.04 – 1.09 3.07e-09 9603 96090 all phecode
735.1 Flat foot Musculoskeletal 1.1 0.941 – 1.28 0.238 189 1910 all phecode
735.2 Acquired toe deformities Musculoskeletal 1.07 1.04 – 1.1 4.13e-06 5070 50712 all phecode
735.21 Hammer toe (acquired) Musculoskeletal 1.06 1.01 – 1.11 0.0133 1929 19324 all phecode
735.23 Hallux rigidus Musculoskeletal 1.07 1.02 – 1.13 0.00841 1555 15527 all phecode
735.3 Hallux valgus (Bunion) Musculoskeletal 1.06 1.03 – 1.08 3.54e-05 6643 66463 all phecode
736 Other acquired deformities of limbs Musculoskeletal 1.09 1.03 – 1.14 0.00155 1627 16282 all phecode
736.2 Acquired deformities of finger Musculoskeletal 0.993 0.873 – 1.13 0.918 248 2476 all phecode
737 Curvature of spine Musculoskeletal 1.08 1.02 – 1.15 0.0108 1128 11300 all phecode
737.3 Kyphoscoliosis and scoliosis Musculoskeletal 1.09 1.02 – 1.16 0.00874 1061 10632 all phecode
738 Other acquired musculoskeletal deformity Musculoskeletal 1.16 1.11 – 1.22 4.69e-10 1904 19058 all phecode
738.4 Acquired spondylolisthesis Musculoskeletal 1.17 1.11 – 1.23 1.74e-08 1513 15147 all phecode
739 Contracture of joint Musculoskeletal 1.09 0.994 – 1.2 0.0655 488 4884 all phecode
740 Osteoarthrosis Musculoskeletal 1.11 1.1 – 1.13 6.54e-63 27707 231603 all phecode
740.1 Osteoarthritis; localized Musculoskeletal 1.1 1.08 – 1.12 8.66e-32 17412 169419 all phecode
740.11 Osteoarthrosis, localized, primary Musculoskeletal 1.09 1.06 – 1.11 1.78e-13 8974 89750 all phecode
740.12 Osteoarthrosis, localized, secondary Musculoskeletal 1.16 1.04 – 1.3 0.00856 348 3474 all phecode
740.2 Osteoarthrosis, generalized Musculoskeletal 1.14 1.04 – 1.24 0.00304 598 5969 all phecode
740.9 Osteoarthrosis NOS Musculoskeletal 1.15 1.13 – 1.17 1.61e-47 12270 122792 all phecode
741 Symptoms and disorders of the joints Musculoskeletal 1.08 1.04 – 1.12 1.56e-05 3563 35648 all phecode
741.1 Ankylosis of joint Musculoskeletal 0.934 0.762 – 1.15 0.515 102 1019 all phecode
741.2 Stiffness of joint Musculoskeletal 1.08 0.998 – 1.18 0.0544 614 6146 all phecode
741.3 Difficulty in walking Musculoskeletal 1.13 0.955 – 1.33 0.156 154 1540 all phecode
741.4 Joint effusions Musculoskeletal 1.09 1.03 – 1.15 0.00147 1418 14197 all phecode
741.5 Hemarthrosis Musculoskeletal 1.03 0.848 – 1.25 0.768 110 1100 all phecode
741.6 Villonodular synovitis Musculoskeletal 1.01 0.771 – 1.31 0.964 54 535 all phecode
742 Derangement of joint, non-traumatic Musculoskeletal 1.09 1.05 – 1.14 4.62e-06 2843 28441 all phecode
742.1 Loose body in joint Musculoskeletal 1.14 1.02 – 1.27 0.0238 333 3337 all phecode
742.2
Pathological, developmental or recurrent
Pathological, developmental or recurrent dislocation
 Musculoskeletal 1.06 0.865 – 1.3 0.564 95 960 all phecode
742.8 Articular cartilage disorder Musculoskeletal 1.1 1 – 1.2 0.0485 500 4996 all phecode
742.9 Other derangement of joint Musculoskeletal 1.08 1.03 – 1.13 0.000729 1993 19926 all phecode
743
Osteoporosis, osteopenia and pathological
Osteoporosis, osteopenia and pathological fracture
 Musculoskeletal 1.06 1.04 – 1.09 9.46e-07 7563 75729 all phecode
743.1 Osteoporosis Musculoskeletal 1.05 1.02 – 1.07 0.000817 6400 64107 all phecode
743.11 Osteoporosis NOS Musculoskeletal 1.04 1.01 – 1.07 0.00427 5549 55604 all phecode
743.13 Other specified osteoporosis Musculoskeletal 1.15 1.05 – 1.25 0.00245 529 5283 all phecode
743.2 Pathologic fracture Musculoskeletal 1.22 1.11 – 1.33 2.76e-05 516 5179 all phecode
743.9
Osteopenia or other disorder of bone and
Osteopenia or other disorder of bone and cartilage
 Musculoskeletal 1.11 1.03 – 1.19 0.00579 815 8144 all phecode
745 Pain in joint Musculoskeletal 1.16 1.13 – 1.19 1.65e-36 7975 79789 all phecode
747 Cardiac and circulatory congenital anomalies Congenital Anomalies 1.08 1.04 – 1.12 0.000136 2802 28058 all phecode
747.1 Cardiac congenital anomalies Congenital Anomalies 1.08 1.03 – 1.12 0.000282 2628 26323 all phecode
747.11 Cardiac shunt/ heart septal defect Congenital Anomalies 1.01 0.926 – 1.1 0.859 584 5838 all phecode
747.12 Valvular heart disease/ heart chambers Congenital Anomalies 0.928 0.808 – 1.07 0.29 235 2358 all phecode
747.13 Congenital anomalies of great vessels Congenital Anomalies 1.11 1.06 – 1.17 2.31e-05 1816 18200 all phecode
747.2
Congenital anomalies of peripheral vascular
Congenital anomalies of peripheral vascular system
 Congenital Anomalies 1.06 0.909 – 1.25 0.44 167 1680 all phecode
748 Anomalies of respiratory system, congenital Congenital Anomalies 1.12 0.852 – 1.48 0.41 51 510 all phecode
749 Congenital anomalies of face and neck Congenital Anomalies 1.14 1.01 – 1.28 0.028 303 3029 all phecode
750 Digestive congenital anomalies Congenital Anomalies 0.946 0.875 – 1.02 0.166 686 6870 all phecode
750.1 Upper gastrointestinal congenital anomalies Congenital Anomalies 0.915 0.816 – 1.03 0.128 327 3263 all phecode
750.13 Congenital anomalies of mouth/tongue Congenital Anomalies 0.884 0.759 – 1.03 0.111 191 1909 all phecode
750.2 Lower gastrointestinal congenital anomalies Congenital Anomalies 0.964 0.865 – 1.07 0.502 356 3574 all phecode
750.21 Congenital anomalies of intestine Congenital Anomalies 0.892 0.78 – 1.02 0.0942 225 2256 all phecode
750.22
Congenital anomaly of gallbladder, bile ducts
Congenital anomaly of gallbladder, bile ducts, liver, pancreas
 Congenital Anomalies 1.08 0.895 – 1.31 0.414 117 1179 all phecode
751 Genitourinary congenital anomalies Congenital Anomalies 1.06 1 – 1.11 0.0454 1527 15286 all phecode
751.1 Congenital anomalies of genital organs Congenital Anomalies 1.03 0.956 – 1.12 0.397 694 6932 all phecode
751.11 Congenital anomalies of female genital organs Congenital Anomalies 1.03 0.933 – 1.14 0.562 455 4546 all phecode
751.12 Congenital anomalies of male genital organs Congenital Anomalies 0.98 0.851 – 1.13 0.782 222 2217 all phecode
751.2 Congenital anomalies of urinary system Congenital Anomalies 1.08 1 – 1.16 0.0411 836 8385 all phecode
751.21 Cystic kidney disease Congenital Anomalies 1.07 0.971 – 1.19 0.164 424 4246 all phecode
751.22 Other specified congenital anomalies of kidney Congenital Anomalies 1.11 0.987 – 1.24 0.0833 333 3346 all phecode
752 Nervous system congenital anomalies Congenital Anomalies 1.12 1 – 1.26 0.0482 328 3307 all phecode
752.1 Neural tube defects Congenital Anomalies 1.11 0.975 – 1.26 0.114 253 2557 all phecode
752.11 Spina bifida Congenital Anomalies 1.15 0.994 – 1.32 0.0602 208 2108 all phecode
752.2
Other specified congenital anomalies of nervous
Other specified congenital anomalies of nervous system
 Congenital Anomalies 1.12 0.886 – 1.42 0.342 78 780 all phecode
753 Congenital anomalies of the eye Congenital Anomalies 1.16 0.968 – 1.4 0.106 127 1270 all phecode
753.1 Congenital cataract and lens anomalies Congenital Anomalies 1.23 0.963 – 1.57 0.0981 76 760 all phecode
754 Congenital musculoskeletal deformities of spine Congenital Anomalies 1.11 0.914 – 1.36 0.283 109 1099 all phecode
755 Congenital anomalies of limbs Congenital Anomalies 1.09 0.984 – 1.2 0.1 425 4276 all phecode
755.1 Congenital deformities of feet Congenital Anomalies 1.03 0.892 – 1.19 0.696 208 2086 all phecode
755.6
Other congenital anomalies of lower limb
Other congenital anomalies of lower limb, including pelvic girdle
 Congenital Anomalies 1.21 1.03 – 1.42 0.0228 160 1620 all phecode
755.61 Congenital hip dysplasia and deformity Congenital Anomalies 1.24 1.01 – 1.53 0.0426 106 1070 all phecode
756 Other congenital musculoskeletal anomalies Congenital Anomalies 1.1 1.01 – 1.2 0.0262 587 5872 all phecode
756.3
Congenital anomalies of muscle, tendon, fascia
Congenital anomalies of muscle, tendon, fascia, and connective tissue
 Congenital Anomalies 1.28 1.02 – 1.6 0.0367 81 810 all phecode
756.5 Congenital osteodystrophies Congenital Anomalies 1.11 1 – 1.22 0.0438 435 4356 all phecode
758 Chromosomal anomalies and genetic disorders Congenital Anomalies 0.995 0.841 – 1.18 0.95 148 1708 all phecode
758.1 Chromosomal anomalies Congenital Anomalies 1.27 0.98 – 1.64 0.0711 60 830 all phecode
759 Other and unspecified congenital anomalies Congenital Anomalies 1.01 0.878 – 1.16 0.914 216 2159 all phecode
759.1 Anomalies of endocrine glands, congenital Congenital Anomalies 0.99 0.808 – 1.21 0.924 96 959 all phecode
760 Back pain Symptoms 1.16 1.13 – 1.18 1.14e-47 11126 111353 all phecode
761 Cervicalgia Symptoms 1.16 1.11 – 1.22 2.69e-09 1791 17901 all phecode
764 Sciatica Symptoms 1.17 1.12 – 1.22 1.24e-12 2372 23732 all phecode
766 Neuralgia, neuritis, and radiculitis NOS Symptoms 1.11 1.05 – 1.18 0.000451 1172 11738 all phecode
770 Myalgia and myositis unspecified Symptoms 1.04 0.961 – 1.13 0.321 631 6311 all phecode
771 Musculoskeletal symptoms referable to limbs Symptoms 1.12 1.04 – 1.2 0.00188 870 8687 all phecode
771.1 Swelling of limb Symptoms 1.12 1.08 – 1.15 9.59e-13 4617 46330 all phecode
772 Symptoms of the muscles Symptoms 1.07 0.988 – 1.16 0.0934 659 6581 all phecode
773 Pain in limb Symptoms 1.13 1.1 – 1.16 6.28e-20 6209 62203 all phecode
780 Hypothermia/Chills Symptoms 1.12 0.957 – 1.31 0.159 171 1719 all phecode
781
Symptoms involving nervous and musculoskeletal
Symptoms involving nervous and musculoskeletal systems
 Symptoms 1.13 1.08 – 1.19 2.72e-07 1870 18715 all phecode
782.3 Edema Symptoms 1.15 1.09 – 1.21 8.81e-08 1642 16450 all phecode
782.6 Pallor and flushing Symptoms 1.25 1.07 – 1.46 0.00489 175 1748 all phecode
783 Fever of unknown origin Symptoms 1.06 1.02 – 1.09 0.00126 3911 39105 all phecode
785 Abdominal pain Symptoms 1.09 1.08 – 1.1 1.36e-58 40080 301686 all phecode
788 Syncope and collapse Symptoms 1.04 1.02 – 1.06 0.000437 9069 90813 all phecode
789 Nausea and vomiting Symptoms 1.09 1.07 – 1.11 1.26e-18 11577 115807 all phecode
790 Nonspecific findings on examination of blood Symptoms 0.991 0.839 – 1.17 0.912 150 1500 all phecode
790.1 Elevated sedimentation rate Symptoms 1.19 0.947 – 1.49 0.137 84 840 all phecode
790.6 Other abnormal blood chemistry Symptoms 1.04 1.01 – 1.07 0.0034 6357 63635 all phecode
791 Gangrene Symptoms 1.08 0.985 – 1.18 0.102 549 5501 all phecode
792
Abnormal Papanicolaou smear of cervix and
Abnormal Papanicolaou smear of cervix and cervical HPV
 Symptoms 1.13 0.918 – 1.38 0.256 98 966 all phecode
793
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of musculoskeletal system
 Symptoms 1.04 0.872 – 1.23 0.682 134 1340 all phecode
793.2
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of other intrathoracic organs (echocardiogram, etc)
 Symptoms 1.01 0.931 – 1.1 0.759 565 5647 all phecode
794
Abnormal results of other function studies
Abnormal results of other function studies (bladder, pancreas, placenta, spleen, etc)
 Symptoms 0.883 0.732 – 1.06 0.193 120 1198 all phecode
797 Shock Symptoms 1.05 0.891 – 1.23 0.572 156 1559 all phecode
797.1 Cardiogenic shock Symptoms 1.03 0.847 – 1.26 0.741 102 1020 all phecode
798 Malaise and fatigue Symptoms 1.07 1.04 – 1.11 9.88e-05 3408 34103 all phecode
798.1 Chronic fatigue syndrome Symptoms 0.991 0.91 – 1.08 0.827 591 5913 all phecode
800 Fracture of lower limb Injuries & Poisonings 1.06 1.04 – 1.09 5.93e-07 7035 70329 all phecode
800.1 Fracture of neck of femur Injuries & Poisonings 1.04 0.991 – 1.09 0.112 1815 18152 all phecode
800.2 Fracture of unspecified part of femur Injuries & Poisonings 1.05 0.892 – 1.22 0.584 170 1693 all phecode
800.3 Fracture of tibia and fibula Injuries & Poisonings 1.09 1.04 – 1.14 0.000179 2158 21577 all phecode
800.4 Fracture of patella Injuries & Poisonings 1.04 0.966 – 1.12 0.298 766 7661 all phecode
801 Fracture of ankle and foot Injuries & Poisonings 1.11 1.06 – 1.16 2.49e-06 2205 22041 all phecode
801.1 Fracture of foot Injuries & Poisonings 1.1 1.05 – 1.15 8.18e-05 1835 18346 all phecode
802 Fracture of pelvis Injuries & Poisonings 1.03 0.955 – 1.11 0.432 718 7185 all phecode
803 Fracture of upper limb Injuries & Poisonings 1.02 0.993 – 1.04 0.172 8288 82880 all phecode
803.1 Fracture of humerus Injuries & Poisonings 1.03 0.982 – 1.09 0.204 1691 16883 all phecode
803.2 Fracture of radius and ulna Injuries & Poisonings 0.988 0.96 – 1.02 0.4 5215 52171 all phecode
803.3 Fracture of clavicle or scapula Injuries & Poisonings 1.09 1.03 – 1.15 0.0012 1518 15186 all phecode
804 Fracture of hand or wrist Injuries & Poisonings 1.06 1.02 – 1.1 0.00213 3339 33384 all phecode
805
Fracture of vertebral column without mention of
Fracture of vertebral column without mention of spinal cord injury
 Injuries & Poisonings 1.05 0.993 – 1.11 0.0862 1358 13565 all phecode
807 Fracture of ribs Injuries & Poisonings 1.14 1.06 – 1.23 0.000342 776 7752 all phecode
809 Fracture of unspecified bones Injuries & Poisonings 1.05 0.996 – 1.12 0.0676 1300 12998 all phecode
817 Concussion Injuries & Poisonings 0.981 0.858 – 1.12 0.773 243 2428 all phecode
818 Intracranial hemorrhage (injury) Injuries & Poisonings 1.12 1.02 – 1.22 0.0145 522 5213 all phecode
819
Skull and face fracture and other intercranial
Skull and face fracture and other intercranial injury
 Injuries & Poisonings 1.1 1.06 – 1.14 1.41e-06 2957 29596 all phecode
823 Torus fracture Injuries & Poisonings 1.1 1.05 – 1.16 0.000152 1673 16710 all phecode
830 Dislocation Injuries & Poisonings 1.15 1.1 – 1.2 2.07e-09 2088 20872 all phecode
835 Internal derangement of knee Injuries & Poisonings 1.07 1.06 – 1.09 2.71e-17 15221 152247 all phecode
836 Traumatic arthropathy Injuries & Poisonings 1.29 1.18 – 1.41 3.85e-08 526 5267 all phecode
840 Sprains and strains Injuries & Poisonings 1.05 0.955 – 1.15 0.316 470 4697 all phecode
850 Hemorrhage or hematoma complicating a procedure Injuries & Poisonings 1.08 1.05 – 1.11 8.54e-08 5259 52626 all phecode
851
Complications of transplants and reattached
Complications of transplants and reattached limbs
 Injuries & Poisonings 1.1 0.936 – 1.3 0.238 157 1567 all phecode
853 Complication of colostomy or enterostomy Injuries & Poisonings 1.14 1.04 – 1.24 0.00652 501 5010 all phecode
854
Complications of cardiac/vascular device
Complications of cardiac/vascular device, implant, and graft
 Injuries & Poisonings 1.17 1.11 – 1.22 4.23e-10 1826 18238 all phecode
857
Mechanical complication of unspecified
Mechanical complication of unspecified genitourinary device, implant, and graft
 Injuries & Poisonings 1.1 1.03 – 1.16 0.00217 1241 12418 all phecode
858 Complication of internal orthopedic device Injuries & Poisonings 1.16 1.12 – 1.21 1.06e-15 3158 31607 all phecode
859
Complication due to other implant and internal
Complication due to other implant and internal device
 Injuries & Poisonings 1.17 1.13 – 1.22 2.89e-18 3259 32599 all phecode
860 Bone marrow or stem cell transplant Neoplasms 0.835 0.655 – 1.06 0.145 68 680 all phecode
870 Open wounds of head; neck; and trunk Injuries & Poisonings 1.12 1.08 – 1.16 3.47e-10 3502 35062 all phecode
870.1 Open wound or laceration of eye or eyelid Injuries & Poisonings 1.02 0.902 – 1.16 0.734 272 2713 all phecode
870.2 Open wound of ear Injuries & Poisonings 1.1 0.955 – 1.27 0.184 196 1949 all phecode
870.3 Other open wound of head and face Injuries & Poisonings 1.12 1.08 – 1.17 1.74e-09 2904 29085 all phecode
870.4 Open wound of nose and sinus Injuries & Poisonings 1.11 0.963 – 1.28 0.151 220 2199 all phecode
870.6 Open wound of neck Injuries & Poisonings 1.02 0.808 – 1.29 0.866 68 678 all phecode
871 Open wounds of extremities Injuries & Poisonings 1.16 1.12 – 1.19 7.4e-19 4063 40648 all phecode
871.1 Open wound of hand except finger(s) Injuries & Poisonings 1.55 1.17 – 2.06 0.00224 53 530 all phecode
871.2 Open wound of finger(s) Injuries & Poisonings 1.11 0.903 – 1.37 0.314 91 900 all phecode
871.3 Open wound of foot except toe(s) alone Injuries & Poisonings 1.12 0.955 – 1.3 0.168 178 1785 all phecode
872 Traumatic amputation Injuries & Poisonings 1.08 0.98 – 1.19 0.122 475 4742 all phecode
873 Broken tooth Injuries & Poisonings 1.02 0.887 – 1.16 0.821 229 2289 all phecode
874 Complication of amputation stump Injuries & Poisonings 1.32 1.13 – 1.55 0.000557 169 1710 all phecode
905
Late effects of musculoskeletal and connective
Late effects of musculoskeletal and connective tissue injuries
 Injuries & Poisonings 1.17 0.998 – 1.38 0.0536 157 1567 all phecode
907 Injuries to the nervous system Injuries & Poisonings 1.15 1.09 – 1.21 1.57e-06 1314 13140 all phecode
915 Superficial injury without mention of infection Injuries & Poisonings 1.07 1.04 – 1.11 1.01e-05 4260 42663 all phecode
916 Contusion Injuries & Poisonings 1.08 1.03 – 1.14 0.00297 1450 14506 all phecode
930 Allergic reaction to food Injuries & Poisonings 1.03 0.883 – 1.19 0.741 179 1807 all phecode
938 Dermatitis due to solar radiation Injuries & Poisonings 0.997 0.898 – 1.11 0.948 389 3899 all phecode
938.2 Chronic dermatitis due to solar radiation Injuries & Poisonings 0.964 0.849 – 1.1 0.574 252 2530 all phecode
939
Atopic/contact dermatitis due to other or
Atopic/contact dermatitis due to other or unspecified
 Dermatologic 1.03 0.989 – 1.08 0.138 2094 20961 all phecode
941 Adverse reaction to serum or vaccine Injuries & Poisonings 1.05 0.917 – 1.2 0.477 225 2249 all phecode
942 Infusion and transfusion reaction Injuries & Poisonings 1.02 0.831 – 1.26 0.835 104 1038 all phecode
946 Anaphylactic shock NOS Injuries & Poisonings 1.17 1.07 – 1.28 0.000376 550 5509 all phecode
947 Urticaria Injuries & Poisonings 1.07 0.957 – 1.19 0.244 371 3707 all phecode
949 Allergies, other Injuries & Poisonings 1.07 0.96 – 1.18 0.228 397 3989 all phecode
952
Spinal cord injury without evidence of spinal
Spinal cord injury without evidence of spinal bone injury
 Injuries & Poisonings 1.06 0.962 – 1.18 0.228 423 4224 all phecode
957 Injury to other and unspecified nerves Injuries & Poisonings 1.19 1.05 – 1.35 0.00546 269 2698 all phecode
958
Certain early complications of trauma or
Certain early complications of trauma or procedure
 Injuries & Poisonings 1.12 1.03 – 1.23 0.0123 491 4926 all phecode
958.1 Postoperative shock Injuries & Poisonings 1.07 0.82 – 1.4 0.61 55 555 all phecode
958.2 Traumatic and surgical subcutaneous emphysema Injuries & Poisonings 1.03 0.82 – 1.29 0.797 74 740 all phecode
960 Poisoning by antibiotics Injuries & Poisonings 1.07 1.06 – 1.09 2.13e-19 18100 181147 all phecode
960.2 Allergy/adverse effect of penicillin Injuries & Poisonings 1.08 1.06 – 1.1 1.28e-19 15846 158623 all phecode
961 Poisoning by other anti-infectives Injuries & Poisonings 1.16 1.05 – 1.28 0.00436 420 4195 all phecode
961.1 Poisoning/allergy of sulfonamides Injuries & Poisonings 1.02 0.955 – 1.1 0.496 869 8703 all phecode
962 Poisoning by hormones and synthetic substitutes Injuries & Poisonings 1.05 0.939 – 1.17 0.41 371 3707 all phecode
962.3
Hormones and synthetic substitutes causing
Hormones and synthetic substitutes causing adverse effects in therapeutic use
 Injuries & Poisonings 1.09 0.978 – 1.22 0.12 364 3638 all phecode
963 Poisoning by primarily systemic agents Injuries & Poisonings 1.23 1.07 – 1.42 0.00293 223 2228 all phecode
964
Poisoning by agents primarily affecting blood
Poisoning by agents primarily affecting blood constituents
 Injuries & Poisonings 1.13 0.994 – 1.27 0.0623 282 2830 all phecode
964.1 Anticoagulants causing adverse effects Injuries & Poisonings 1.14 1 – 1.29 0.0429 276 2770 all phecode
965
Poisoning by analgesics, antipyretics, and
Poisoning by analgesics, antipyretics, and antirheumatics
 Injuries & Poisonings 1.14 1.11 – 1.17 2.69e-23 6082 60875 all phecode
965.1
Opiates and related narcotics causing adverse
Opiates and related narcotics causing adverse effects in therapeutic use
 Injuries & Poisonings 1.09 1.03 – 1.16 0.00507 1144 11447 all phecode
965.2
Antirheumatics causing adverse effects in
Antirheumatics causing adverse effects in therapeutic use
 Injuries & Poisonings 1.34 1.22 – 1.47 1.59e-09 476 4767 all phecode
965.3
Salicylates causing adverse effects in
Salicylates causing adverse effects in therapeutic use
 Injuries & Poisonings 1.34 1.21 – 1.48 2.83e-08 403 4045 all phecode
966
Poisoning by anticonvulsants and
Poisoning by anticonvulsants and anti-Parkinsonism drugs
 Injuries & Poisonings 1.18 1.08 – 1.29 0.00031 512 5123 all phecode
967
Adverse effects of sedatives or other central
Adverse effects of sedatives or other central nervous system depressants and anesthetics
 Injuries & Poisonings 1.07 0.981 – 1.16 0.128 583 5843 all phecode
969 Poisoning by psychotropic agents Injuries & Poisonings 1.3 1.24 – 1.37 1.27e-28 1950 19519 all phecode
971
Poisoning by drugs primarily affecting the
Poisoning by drugs primarily affecting the autonomic nervous system
 Injuries & Poisonings 1.22 1.05 – 1.41 0.00808 190 1908 all phecode
972
Poisoning by agents primarily affecting the
Poisoning by agents primarily affecting the cardiovascular system
 Injuries & Poisonings 1.35 1.19 – 1.53 2.24e-06 271 2717 all phecode
972.6 Antihypertensive agents causing adverse effects Injuries & Poisonings 1.35 1.07 – 1.69 0.0104 84 849 all phecode
973
Poisoning by agents primarily affecting the
Poisoning by agents primarily affecting the gastrointestinal system
 Injuries & Poisonings 1.44 1.18 – 1.76 0.000364 108 1080 all phecode
974
Poisoning by water, mineral, and uric acid
Poisoning by water, mineral, and uric acid metabolism drugs
 Injuries & Poisonings 1.26 1.02 – 1.55 0.0349 101 1018 all phecode
975
Poisoning by agents primarily acting on the
Poisoning by agents primarily acting on the smooth and skeletal muscles and respiratory system
 Injuries & Poisonings 1.39 1.08 – 1.8 0.0109 64 640 all phecode
976
Poisoning by agents primarily affecting skin &
Poisoning by agents primarily affecting skin & mucous membrane, ophthalmological, otorhinolaryngological, & dental drugs
 Injuries & Poisonings 1.43 1.09 – 1.89 0.0104 58 580 all phecode
977 Personal history of allergy to medicinal agents Injuries & Poisonings 1.19 1.04 – 1.36 0.00957 234 2337 all phecode
979 Adverse drug events and drug allergies Injuries & Poisonings 1.24 1.15 – 1.35 6.23e-08 698 6966 all phecode
981
Toxic effect of (non-ethyl) alcohol and
Toxic effect of (non-ethyl) alcohol and petroleum and other solvents
 Injuries & Poisonings 1.36 1.17 – 1.57 5.1e-05 200 1999 all phecode
986 Toxic effect of carbon monoxide Injuries & Poisonings 1.35 1.04 – 1.74 0.0221 62 620 all phecode
987 Toxic effect of other gases, fumes, or vapors Injuries & Poisonings 1.28 1.05 – 1.57 0.017 105 1049 all phecode
988 Toxic effect of noxious substances eaten as food Injuries & Poisonings 0.97 0.806 – 1.17 0.746 111 1128 all phecode
989
Toxic effect of other substances, chiefly
Toxic effect of other substances, chiefly nonmedicinal as to source
 Injuries & Poisonings 1.02 0.823 – 1.27 0.851 89 890 all phecode
990 Effects radiation NOS Injuries & Poisonings 1.08 1.04 – 1.12 8.49e-05 3113 31140 all phecode
994 Sepsis and SIRS Injuries & Poisonings 1.03 0.991 – 1.07 0.142 3028 30268 all phecode
994.2 Sepsis Injuries & Poisonings 1.03 0.991 – 1.07 0.142 3028 30268 all phecode
008 Intestinal infection Infectious Diseases 1.08 1.05 – 1.12 1.61e-05 3177 34779 exclusion phecode
008.5 Bacterial enteritis Infectious Diseases 1.1 1.03 – 1.18 0.00458 962 10653 exclusion phecode
008.52 Intestinal infection due to C. difficile Infectious Diseases 1.06 0.926 – 1.21 0.399 230 2513 exclusion phecode
008.6 Viral Enteritis Infectious Diseases 1.09 0.967 – 1.22 0.164 316 3341 exclusion phecode
008.7 Intestinal infection due to protozoa Infectious Diseases 0.814 0.525 – 1.26 0.357 23 208 exclusion phecode
010 Tuberculosis Infectious Diseases 0.951 0.714 – 1.27 0.73 44 635 exclusion phecode
038 Septicemia Infectious Diseases 1.01 0.96 – 1.07 0.626 1419 15777 exclusion phecode
038.1 Gram negative septicemia Infectious Diseases 1.05 0.929 – 1.18 0.447 307 3119 exclusion phecode
038.2 Gram positive septicemia Infectious Diseases 1.08 0.913 – 1.27 0.386 158 1883 exclusion phecode
041 Bacterial infection NOS Infectious Diseases 1.1 1.07 – 1.14 3.29e-09 4072 46494 exclusion phecode
041.1 Staphylococcus infections Infectious Diseases 1.06 0.99 – 1.13 0.101 1028 11962 exclusion phecode
041.2 Streptococcus infection Infectious Diseases 1.09 0.998 – 1.19 0.0543 558 6335 exclusion phecode
041.4 E. coli Infectious Diseases 1.12 1.05 – 1.2 0.000922 961 10739 exclusion phecode
053 Herpes zoster Infectious Diseases 1.09 0.911 – 1.29 0.36 139 1617 exclusion phecode
053.1 Herpes zoster with nervous system complications Infectious Diseases 1.1 0.753 – 1.59 0.633 29 359 exclusion phecode
054 Herpes simplex Infectious Diseases 1.23 0.963 – 1.56 0.0983 78 801 exclusion phecode
070 Viral hepatitis Infectious Diseases 1.06 0.898 – 1.25 0.488 144 2278 exclusion phecode
070.1 Viral hepatitis A Infectious Diseases 0.967 0.633 – 1.48 0.878 22 282 exclusion phecode
070.2 Viral hepatitis B Infectious Diseases 1.09 0.784 – 1.51 0.609 39 485 exclusion phecode
070.3 Viral hepatitis C Infectious Diseases 1.21 0.884 – 1.65 0.237 36 1048 exclusion phecode
070.4 Chronic hepatitis Infectious Diseases 1.01 0.83 – 1.22 0.946 113 1132 exclusion phecode
070.9 Hepatitis NOS Infectious Diseases 1.18 0.998 – 1.39 0.0533 147 1607 exclusion phecode
071 Human immunodeficiency virus [HIV] disease Infectious Diseases 1.1 0.804 – 1.52 0.538 39 543 exclusion phecode
071.1 HIV infection, symptomatic Infectious Diseases 1.04 0.735 – 1.48 0.816 33 438 exclusion phecode
078 Viral warts & HPV Infectious Diseases 0.982 0.881 – 1.09 0.737 358 4009 exclusion phecode
079 Viral infection Infectious Diseases 1.06 0.993 – 1.12 0.0827 1100 11167 exclusion phecode
079.1 Varicella infection Infectious Diseases 0.906 0.606 – 1.35 0.629 24 281 exclusion phecode
080 Postoperative infection Infectious Diseases 1.04 0.984 – 1.1 0.172 1460 17445 exclusion phecode
081
Infection/inflammation of internal prosthetic
Infection/inflammation of internal prosthetic device; implant; and graft
 Infectious Diseases 1.09 1.01 – 1.17 0.0197 813 9364 exclusion phecode
090
Sexually transmitted infections (not HIV or
Sexually transmitted infections (not HIV or hepatitis)
 Infectious Diseases 1 0.681 – 1.48 0.991 29 264 exclusion phecode
1000 Burns Injuries & Poisonings 0.981 0.851 – 1.13 0.788 215 2207 exclusion phecode
1001 Foreign body injury Injuries & Poisonings 0.983 0.889 – 1.09 0.741 418 4598 exclusion phecode
1002
Symptoms concerning nutrition, metabolism, and
Symptoms concerning nutrition, metabolism, and development
 Injuries & Poisonings 1.05 1 – 1.1 0.0404 1908 21313 exclusion phecode
1004
Other signs and symptoms involving emotional
Other signs and symptoms involving emotional state
 Injuries & Poisonings 1.27 1.03 – 1.58 0.0285 86 1181 exclusion phecode
1005 Other symptoms Injuries & Poisonings 1.07 0.971 – 1.17 0.179 467 5561 exclusion phecode
1006 Crushing injury Injuries & Poisonings 1.05 0.824 – 1.33 0.71 70 957 exclusion phecode
1007 Injury to blood vessels Injuries & Poisonings 0.992 0.786 – 1.25 0.948 80 964 exclusion phecode
1008 Crushing or internal injury to organs Injuries & Poisonings 1.15 1.02 – 1.29 0.0185 315 3778 exclusion phecode
1009 Injury, NOS Injuries & Poisonings 1.06 1.02 – 1.1 0.00146 3040 32507 exclusion phecode
1010 Other tests Injuries & Poisonings 1.04 0.998 – 1.09 0.0589 2152 23132 exclusion phecode
1011 Complications of surgical and medical procedures Injuries & Poisonings 1.09 1.05 – 1.13 9.41e-06 3153 35115 exclusion phecode
1012 Late effect Injuries & Poisonings 0.932 0.683 – 1.27 0.659 46 427 exclusion phecode
1013 Asphyxia and hypoxemia Injuries & Poisonings 0.983 0.799 – 1.21 0.875 94 1174 exclusion phecode
1014 Effects of heat, cold and air pressure Injuries & Poisonings 0.962 0.656 – 1.41 0.843 27 273 exclusion phecode
1015 Effects of other external causes Injuries & Poisonings 1.11 1.05 – 1.17 0.000343 1374 16745 exclusion phecode
1019
Other ill-defined and unknown causes of
Other ill-defined and unknown causes of morbidity and mortality
 Injuries & Poisonings 1.06 1.03 – 1.09 1e-05 5742 62339 exclusion phecode
110 Dermatophytosis / Dermatomycosis Infectious Diseases 1.1 0.889 – 1.37 0.371 91 1032 exclusion phecode
110.1 Dermatophytosis Infectious Diseases 1.09 0.878 – 1.36 0.433 90 999 exclusion phecode
110.11 Dermatophytosis of nail Infectious Diseases 1.08 0.736 – 1.59 0.688 27 281 exclusion phecode
110.12 Althete's foot Infectious Diseases 1.22 0.885 – 1.67 0.227 40 502 exclusion phecode
112 Candidiasis Infectious Diseases 1.08 0.997 – 1.17 0.0602 673 8316 exclusion phecode
117 Mycoses Infectious Diseases 1.1 0.885 – 1.36 0.401 92 1074 exclusion phecode
117.4 Aspergillosis Infectious Diseases 0.969 0.749 – 1.25 0.811 66 628 exclusion phecode
130 Spirochetal infection Infectious Diseases 1.11 0.745 – 1.64 0.616 29 262 exclusion phecode
133 Arthropod-borne diseases Infectious Diseases 1.27 0.875 – 1.84 0.208 31 254 exclusion phecode
134 Helminthiases Infectious Diseases 1.62 1.2 – 2.19 0.00174 45 539 exclusion phecode
134.1 Intestinal helminthiases Infectious Diseases 1.55 1.12 – 2.14 0.00833 38 436 exclusion phecode
136 Other infectious and parasitic diseases Infectious Diseases 0.983 0.797 – 1.21 0.869 90 790 exclusion phecode
145 Cancer of mouth Neoplasms 1.01 0.864 – 1.19 0.886 167 2371 exclusion phecode
145.2 Cancer of tongue Neoplasms 1.05 0.837 – 1.31 0.69 87 1121 exclusion phecode
145.3 Cancer of major salivary glands Neoplasms 0.962 0.685 – 1.35 0.824 38 404 exclusion phecode
145.5 Cancer of the mouth floor Neoplasms 1.5 0.762 – 2.96 0.24 5 201 exclusion phecode
149 Cancer of larynx, pharynx, nasal cavities Neoplasms 1.04 0.867 – 1.25 0.672 121 2266 exclusion phecode
149.1 Cancer of oropharynx Neoplasms 1.05 0.783 – 1.4 0.759 47 962 exclusion phecode
149.4 Cancer of larynx Neoplasms 1.14 0.822 – 1.59 0.426 36 868 exclusion phecode
149.9 Cancer of of nasal cavities Neoplasms 1.06 0.692 – 1.61 0.797 22 196 exclusion phecode
150 Cancer of esophagus Neoplasms 0.993 0.855 – 1.15 0.922 175 2710 exclusion phecode
151 Cancer of stomach Neoplasms 1.01 0.857 – 1.18 0.949 158 2000 exclusion phecode
153 Colorectal cancer Neoplasms 0.969 0.919 – 1.02 0.244 1522 16806 exclusion phecode
153.2 Colon cancer Neoplasms 1 0.938 – 1.07 0.994 1047 11461 exclusion phecode
153.3
Malignant neoplasm of rectum, rectosigmoid
Malignant neoplasm of rectum, rectosigmoid junction, and anus
 Neoplasms 0.951 0.88 – 1.03 0.203 699 7933 exclusion phecode
155 Cancer of liver and intrahepatic bile duct Neoplasms 1.05 0.873 – 1.27 0.597 120 1459 exclusion phecode
155.1 Malignant neoplasm of liver, primary Neoplasms 0.854 0.626 – 1.17 0.32 48 585 exclusion phecode
157 Pancreatic cancer Neoplasms 1.04 0.907 – 1.19 0.572 223 2531 exclusion phecode
158
Neoplasm of unspecified nature of digestive
Neoplasm of unspecified nature of digestive system
 Neoplasms 0.936 0.837 – 1.05 0.244 343 3933 exclusion phecode
159
Malignant neoplasm of other and ill-defined
Malignant neoplasm of other and ill-defined sites within the digestive organs and peritoneum
 Neoplasms 0.998 0.952 – 1.05 0.95 1833 20591 exclusion phecode
159.2
Malignant neoplasm of small intestine
Malignant neoplasm of small intestine, including duodenum
 Neoplasms 1.01 0.791 – 1.3 0.919 71 687 exclusion phecode
159.3
Malignant neoplasm of gallbladder and
Malignant neoplasm of gallbladder and extrahepatic bile ducts
 Neoplasms 1 0.788 – 1.27 0.988 68 799 exclusion phecode
159.4
Malignant neoplasm of retroperitoneum and
Malignant neoplasm of retroperitoneum and peritoneum
 Neoplasms 1.04 0.828 – 1.3 0.751 84 766 exclusion phecode
164 Cancer of intrathoracic organs Neoplasms 0.843 0.529 – 1.34 0.473 22 225 exclusion phecode
165 Cancer within the respiratory system Neoplasms 1.06 0.961 – 1.18 0.233 394 10584 exclusion phecode
165.1 Cancer of bronchus; lung Neoplasms 1.08 0.955 – 1.23 0.212 245 8453 exclusion phecode
170 Cancer of bone and connective tissue Neoplasms 1 0.856 – 1.18 0.961 161 1671 exclusion phecode
170.1 Bone cancer Neoplasms 1.33 0.958 – 1.85 0.0889 37 494 exclusion phecode
170.2 Cancer of connective tissue Neoplasms 0.957 0.803 – 1.14 0.62 133 1272 exclusion phecode
172 Skin cancer Neoplasms 1.01 0.979 – 1.04 0.609 5307 50279 exclusion phecode
172.1 Melanomas of skin, dx or hx Neoplasms 1.02 0.96 – 1.09 0.517 1159 10294 exclusion phecode
172.11 Melanomas of skin Neoplasms 1.02 0.964 – 1.09 0.436 1173 10450 exclusion phecode
172.2 Other non-epithelial cancer of skin Neoplasms 1 0.968 – 1.03 0.978 4234 40589 exclusion phecode
172.3 Carcinoma in situ of skin Neoplasms 1.05 0.92 – 1.19 0.482 247 2505 exclusion phecode
173 Neoplasm of uncertain behavior of skin Neoplasms 0.957 0.75 – 1.22 0.721 73 773 exclusion phecode
174 Breast cancer Neoplasms 1.01 0.98 – 1.04 0.561 5300 54872 exclusion phecode
174.1 Breast cancer [female] Neoplasms 1.01 0.984 – 1.04 0.382 5232 54081 exclusion phecode
174.11 Malignant neoplasm of female breast Neoplasms 1.01 0.983 – 1.04 0.411 4903 50986 exclusion phecode
174.3 Neoplasm of uncertain behavior of breast Neoplasms 0.863 0.653 – 1.14 0.3 51 490 exclusion phecode
175 Acquired absence of breast Neoplasms 0.99 0.926 – 1.06 0.778 944 10497 exclusion phecode
180 Cervical cancer and dysplasia Neoplasms 1.04 0.972 – 1.12 0.237 846 9684 exclusion phecode
180.1 Cervical cancer Neoplasms 0.998 0.819 – 1.22 0.986 108 1156 exclusion phecode
180.3
Cervical intraepithelial neoplasia [CIN]
Cervical intraepithelial neoplasia [CIN] [Cervical dysplasia]
 Neoplasms 1.04 0.967 – 1.12 0.298 795 9250 exclusion phecode
182 Malignant neoplasm of uterus Neoplasms 1.01 0.931 – 1.1 0.783 621 5471 exclusion phecode
184 Cancer of other female genital organs Neoplasms 0.979 0.898 – 1.07 0.638 589 6068 exclusion phecode
184.1
Malignant neoplasm of ovary and other uterine
Malignant neoplasm of ovary and other uterine adnexa
 Neoplasms 0.974 0.881 – 1.08 0.609 436 4284 exclusion phecode
184.11 Malignant neoplasm of ovary Neoplasms 0.981 0.887 – 1.09 0.712 426 4154 exclusion phecode
184.2
Cancer of other female genital organs
Cancer of other female genital organs (excluding uterus and ovary)
 Neoplasms 0.978 0.801 – 1.19 0.823 110 1305 exclusion phecode
185 Cancer of prostate Neoplasms 1.02 0.973 – 1.07 0.409 1930 17672 exclusion phecode
187 Cancer of other male genital organs Neoplasms 0.964 0.819 – 1.13 0.655 157 1642 exclusion phecode
187.1
Malignant neoplasm of unspecified male genital
Malignant neoplasm of unspecified male genital organ
 Neoplasms 0.983 0.629 – 1.54 0.94 25 230 exclusion phecode
187.2 Malignant neoplasm of testis Neoplasms 0.885 0.726 – 1.08 0.226 108 1089 exclusion phecode
187.8
Neoplasm of uncertain behavior of male genital
Neoplasm of uncertain behavior of male genital organs
 Neoplasms 0.918 0.669 – 1.26 0.598 39 378 exclusion phecode
189
Cancer of urinary organs (incl. kidney and
Cancer of urinary organs (incl. kidney and bladder)
 Neoplasms 1.03 0.969 – 1.1 0.339 1112 14382 exclusion phecode
189.1 Cancer of kidney and renal pelvis Neoplasms 1.03 0.915 – 1.15 0.659 322 3728 exclusion phecode
189.11 Malignant neoplasm of kidney, except pelvis Neoplasms 1.01 0.894 – 1.13 0.925 307 3572 exclusion phecode
189.12 Malignant neoplasm of renal pelvis Neoplasms 1.38 0.901 – 2.11 0.139 22 221 exclusion phecode
189.2 Cancer of bladder Neoplasms 0.97 0.891 – 1.06 0.478 572 8283 exclusion phecode
189.21 Malignant neoplasm of bladder Neoplasms 0.997 0.909 – 1.09 0.956 482 7337 exclusion phecode
189.4 Malignant neoplasm of other urinary organs Neoplasms 0.988 0.728 – 1.34 0.937 47 482 exclusion phecode
190 Cancer of eye Neoplasms 0.985 0.776 – 1.25 0.903 75 652 exclusion phecode
191
Manlignant and unknown neoplasms of brain and
Manlignant and unknown neoplasms of brain and nervous system
 Neoplasms 0.988 0.865 – 1.13 0.855 251 2591 exclusion phecode
191.1 Cancer of brain and nervous system Neoplasms 0.977 0.843 – 1.13 0.753 209 2114 exclusion phecode
191.11 Cancer of brain Neoplasms 1.01 0.862 – 1.18 0.931 186 1939 exclusion phecode
193 Thyroid cancer Neoplasms 0.934 0.786 – 1.11 0.435 136 1451 exclusion phecode
194 Cancer of other endocrine glands Neoplasms 0.727 0.512 – 1.03 0.0757 31 359 exclusion phecode
195 Cancer, suspected or other Neoplasms 1.03 1 – 1.06 0.0254 5912 62463 exclusion phecode
195.1 Malignant neoplasm, other Neoplasms 1.03 1.01 – 1.06 0.0197 5647 59995 exclusion phecode
197 Chemotherapy Neoplasms 1.06 1.03 – 1.08 4.12e-06 7740 84536 exclusion phecode
198 Secondary malignant neoplasm Neoplasms 0.992 0.957 – 1.03 0.685 3219 37209 exclusion phecode
198.1 Secondary malignancy of lymph nodes Neoplasms 0.964 0.92 – 1.01 0.131 1900 21401 exclusion phecode
198.2 Secondary malignancy of respiratory organs Neoplasms 0.997 0.924 – 1.08 0.938 729 8750 exclusion phecode
198.3
Secondary malignant neoplasm of digestive
Secondary malignant neoplasm of digestive systems
 Neoplasms 1 0.922 – 1.09 0.946 601 6098 exclusion phecode
198.4 Secondary malignant neoplasm of liver Neoplasms 1.05 0.978 – 1.12 0.187 904 10195 exclusion phecode
198.5 Secondary malignancy of brain/spine Neoplasms 0.978 0.853 – 1.12 0.755 222 3326 exclusion phecode
198.6 Secondary malignancy of bone Neoplasms 1.04 0.96 – 1.13 0.338 667 8166 exclusion phecode
198.7 Secondary malignant neoplasm of skin Neoplasms 1.09 0.855 – 1.4 0.481 68 735 exclusion phecode
199 Neoplasm of uncertain behavior Neoplasms 1.12 1.02 – 1.22 0.0154 523 5675 exclusion phecode
199.4 Neurofibromatosis Neoplasms 1.05 0.772 – 1.43 0.754 38 415 exclusion phecode
200 Myeloproliferative disease Neoplasms 1.03 0.92 – 1.16 0.594 325 3723 exclusion phecode
200.1 Polycythemia vera Neoplasms 1.16 0.959 – 1.4 0.128 118 1391 exclusion phecode
201 Hodgkin's disease Neoplasms 0.969 0.781 – 1.2 0.779 87 1050 exclusion phecode
202 Cancer of other lymphoid, histiocytic tissue Neoplasms 1.01 0.937 – 1.08 0.871 835 8401 exclusion phecode
202.2 Non-Hodgkins lymphoma Neoplasms 0.974 0.899 – 1.06 0.523 666 6726 exclusion phecode
202.21 Nodular lymphoma Neoplasms 0.886 0.746 – 1.05 0.171 152 1391 exclusion phecode
202.24 Large cell lymphoma Neoplasms 0.974 0.852 – 1.11 0.699 236 2197 exclusion phecode
204 Leukemia Neoplasms 0.967 0.888 – 1.05 0.432 589 6010 exclusion phecode
204.1 Lymphoid leukemia Neoplasms 0.847 0.728 – 0.987 0.0329 186 2061 exclusion phecode
204.11 Lymphoid leukemia, acute Neoplasms 0.869 0.567 – 1.33 0.518 23 186 exclusion phecode
204.12 Lymphoid leukemia, chronic Neoplasms 0.828 0.704 – 0.973 0.0223 165 1806 exclusion phecode
204.2 Myeloid leukemia Neoplasms 0.936 0.8 – 1.1 0.412 166 1705 exclusion phecode
204.21 Myeloid leukemia, acute Neoplasms 0.92 0.757 – 1.12 0.401 113 1190 exclusion phecode
204.22 Myeloid leukemia, chronic Neoplasms 0.942 0.718 – 1.24 0.666 56 554 exclusion phecode
204.4 Multiple myeloma Neoplasms 1.02 0.884 – 1.19 0.746 198 1981 exclusion phecode
208 Benign neoplasm of colon Neoplasms 1.02 0.989 – 1.04 0.262 6119 72426 exclusion phecode
210 Benign neoplasm of lip, oral cavity, and pharynx Neoplasms 1.06 0.948 – 1.19 0.303 324 3798 exclusion phecode
211
Benign neoplasm of other parts of digestive
Benign neoplasm of other parts of digestive system
 Neoplasms 1.05 1 – 1.09 0.0438 2251 20415 exclusion phecode
212
Benign neoplasm of respiratory and
Benign neoplasm of respiratory and intrathoracic organs
 Neoplasms 1.14 0.946 – 1.37 0.17 116 1317 exclusion phecode
213 Benign neoplasm of bone and articular cartilage Neoplasms 1.09 0.908 – 1.31 0.357 119 1267 exclusion phecode
214 Lipoma Neoplasms 1.09 1.05 – 1.14 5.97e-05 2214 23879 exclusion phecode
214.1 Lipoma of skin and subcutaneous tissue Neoplasms 1.1 1.05 – 1.16 0.000206 1650 17881 exclusion phecode
215
Other benign neoplasm of connective and other
Other benign neoplasm of connective and other soft tissue
 Neoplasms 1.04 0.938 – 1.14 0.486 427 4424 exclusion phecode
216 Benign neoplasm of skin Neoplasms 1.02 0.985 – 1.06 0.238 3109 30604 exclusion phecode
217 Vascular hamartomas and non-neoplastic nevi Neoplasms 0.983 0.855 – 1.13 0.813 216 2471 exclusion phecode
217.1 Nevus, non-neoplastic Neoplasms 0.97 0.839 – 1.12 0.685 207 2282 exclusion phecode
218 Benign neoplasm of uterus Neoplasms 1.03 1 – 1.07 0.0365 4555 44195 exclusion phecode
218.1 Uterine leiomyoma Neoplasms 1.03 1 – 1.06 0.0462 4633 45030 exclusion phecode
218.2 Other benign neoplasm of uterus Neoplasms 1.04 0.892 – 1.22 0.591 164 1490 exclusion phecode
220 Benign neoplasm of ovary Neoplasms 0.984 0.906 – 1.07 0.704 612 6346 exclusion phecode
221 Benign neoplasm of other female genital organs Neoplasms 0.88 0.717 – 1.08 0.22 96 997 exclusion phecode
222 Benign neoplasm of male genital organs Neoplasms 1.16 0.874 – 1.55 0.299 58 521 exclusion phecode
223
Benign neoplasm of kidney and other urinary
Benign neoplasm of kidney and other urinary organs
 Neoplasms 0.84 0.642 – 1.1 0.204 47 633 exclusion phecode
224 Benign neoplasm of eye Neoplasms 0.886 0.651 – 1.21 0.442 50 505 exclusion phecode
224.1 Benign neoplasm of eye, uveal Neoplasms 0.866 0.558 – 1.34 0.521 24 249 exclusion phecode
225
Benign neoplasm of brain and other parts of
Benign neoplasm of brain and other parts of nervous system
 Neoplasms 1.02 0.908 – 1.14 0.764 343 3244 exclusion phecode
225.1
Benign neoplasm of brain, cranial nerves
Benign neoplasm of brain, cranial nerves, meninges
 Neoplasms 0.998 0.887 – 1.12 0.978 317 3067 exclusion phecode
225.2 Benign neoplasm of spinal cord, meninges Neoplasms 1.21 0.846 – 1.74 0.293 30 267 exclusion phecode
226 Benign neoplasm of thyroid glands Neoplasms 0.992 0.829 – 1.19 0.929 127 1107 exclusion phecode
227
Benign neoplasm of other endocrine glands and
Benign neoplasm of other endocrine glands and related structures
 Neoplasms 1.06 0.942 – 1.18 0.355 333 3441 exclusion phecode
227.1 Benign neoplasm of adrenal gland Neoplasms 0.898 0.665 – 1.21 0.482 46 733 exclusion phecode
227.2 Benign neoplasm of parathyroid gland Neoplasms 0.974 0.826 – 1.15 0.755 152 1532 exclusion phecode
227.3
Benign neoplasm of pituitary gland and
Benign neoplasm of pituitary gland and craniopharyngeal duct (pouch)
 Neoplasms 1.29 1.07 – 1.56 0.00878 135 1220 exclusion phecode
228 Hemangioma and lymphangioma, any site Neoplasms 0.954 0.877 – 1.04 0.27 609 6262 exclusion phecode
229 Benign neoplasm of unspecified sites Neoplasms 1.04 0.976 – 1.12 0.213 964 9633 exclusion phecode
240 Simple and unspecified goiter Endocrine/metabolic 1.01 0.888 – 1.15 0.895 257 2549 exclusion phecode
241 Nontoxic nodular goiter Endocrine/metabolic 1.04 0.95 – 1.15 0.371 468 4632 exclusion phecode
241.1 Nontoxic uninodular goiter Endocrine/metabolic 0.955 0.823 – 1.11 0.543 191 1943 exclusion phecode
241.2 Nontoxic multinodular goiter Endocrine/metabolic 1.07 0.953 – 1.21 0.243 288 2851 exclusion phecode
242 Thyrotoxicosis with or without goiter Endocrine/metabolic 0.97 0.894 – 1.05 0.457 650 7632 exclusion phecode
242.1 Graves' disease Endocrine/metabolic 0.831 0.698 – 0.99 0.0382 138 1899 exclusion phecode
242.2 Toxic multinodular goiter Endocrine/metabolic 0.961 0.681 – 1.36 0.82 34 367 exclusion phecode
242.3 Exophthalmos Endocrine/metabolic 0.983 0.717 – 1.35 0.914 39 556 exclusion phecode
244 Hypothyroidism Endocrine/metabolic 1.07 1.04 – 1.1 5.43e-07 5674 60173 exclusion phecode
244.1 Secondary hypothyroidism Endocrine/metabolic 0.994 0.902 – 1.1 0.906 435 4614 exclusion phecode
244.2 Acquired hypothyroidism Endocrine/metabolic 1.17 0.843 – 1.63 0.344 39 407 exclusion phecode
244.4 Hypothyroidism NOS Endocrine/metabolic 1.08 1.05 – 1.11 1.86e-07 5412 57706 exclusion phecode
245 Thyroiditis Endocrine/metabolic 1.11 0.923 – 1.33 0.269 132 1215 exclusion phecode
245.2 Chronic thyroiditis Endocrine/metabolic 1.13 0.914 – 1.39 0.265 102 945 exclusion phecode
245.21 Chronic lymphocytic thyroiditis Endocrine/metabolic 1.11 0.896 – 1.38 0.333 97 912 exclusion phecode
246 Other disorders of thyroid Endocrine/metabolic 0.988 0.841 – 1.16 0.882 165 1670 exclusion phecode
250 Diabetes mellitus Endocrine/metabolic 1.1 1.07 – 1.13 2.88e-12 6268 70032 exclusion phecode
250.1 Type 1 diabetes Endocrine/metabolic 1.08 1.01 – 1.16 0.0221 944 10431 exclusion phecode
250.11 Type 1 diabetes with ketoacidosis Endocrine/metabolic 1.16 0.934 – 1.44 0.181 93 973 exclusion phecode
250.12 Type 1 diabetes with renal manifestations Endocrine/metabolic 1.33 0.894 – 1.97 0.161 25 311 exclusion phecode
250.13 Type 1 diabetes with ophthalmic manifestations Endocrine/metabolic 1.12 0.952 – 1.31 0.175 167 1846 exclusion phecode
250.14 Type 1 diabetes with neurological manifestations Endocrine/metabolic 1.06 0.804 – 1.39 0.696 53 630 exclusion phecode
250.2 Type 2 diabetes Endocrine/metabolic 1.11 1.08 – 1.14 2.82e-14 5550 63639 exclusion phecode
250.21 Type 2 diabetes with ketoacidosis Endocrine/metabolic 1.2 0.887 – 1.62 0.237 42 396 exclusion phecode
250.22 Type 2 diabetes with renal manifestations Endocrine/metabolic 1.05 0.819 – 1.34 0.711 63 715 exclusion phecode
250.23 Type 2 diabetes with ophthalmic manifestations Endocrine/metabolic 1.1 0.975 – 1.23 0.124 322 3629 exclusion phecode
250.24 Type 2 diabetes with neurological manifestations Endocrine/metabolic 1.1 0.939 – 1.29 0.238 161 1838 exclusion phecode
250.4 Abnormal glucose Endocrine/metabolic 0.994 0.868 – 1.14 0.933 231 2664 exclusion phecode
250.41 Impaired fasting glucose Endocrine/metabolic 0.966 0.782 – 1.19 0.75 95 1012 exclusion phecode
250.42 Other abnormal glucose Endocrine/metabolic 1.02 0.855 – 1.21 0.834 135 1665 exclusion phecode
250.5 Glycosuria or Acetonuria Endocrine/metabolic 1.28 0.976 – 1.67 0.0748 59 535 exclusion phecode
250.6 Polyneuropathy in diabetes Endocrine/metabolic 1.16 0.964 – 1.4 0.115 113 1278 exclusion phecode
250.7 Diabetic retinopathy Endocrine/metabolic 1.09 0.988 – 1.2 0.0844 455 4880 exclusion phecode
251.1 Hypoglycemia Endocrine/metabolic 1.05 0.939 – 1.18 0.38 320 3507 exclusion phecode
252 Disorders of parathyroid gland Endocrine/metabolic 1 0.897 – 1.11 1 359 3508 exclusion phecode
252.1 Hyperparathyroidism Endocrine/metabolic 1.01 0.899 – 1.13 0.903 320 3129 exclusion phecode
252.2 Hypoparathyroidism Endocrine/metabolic 0.808 0.63 – 1.04 0.0948 62 581 exclusion phecode
253
Disorders of the pituitary gland and its
Disorders of the pituitary gland and its hypothalamic control
 Endocrine/metabolic 1.06 0.935 – 1.21 0.353 262 2561 exclusion phecode
253.1 Pituitary hyperfunction Endocrine/metabolic 1.2 0.942 – 1.53 0.14 75 702 exclusion phecode
253.11 Acromegaly and gigantism Endocrine/metabolic 0.98 0.681 – 1.41 0.914 34 367 exclusion phecode
253.2 Pituitary hypofunction Endocrine/metabolic 0.996 0.809 – 1.23 0.971 103 949 exclusion phecode
253.3 Diabetes insipidus Endocrine/metabolic 1.12 0.799 – 1.56 0.517 40 390 exclusion phecode
253.7 Other disorders of neurohypophysis Endocrine/metabolic 1.1 0.834 – 1.45 0.498 51 598 exclusion phecode
255 Disorders of adrenal glands Endocrine/metabolic 1.01 0.88 – 1.15 0.934 239 2564 exclusion phecode
255.1 Adrenal hyperfunction Endocrine/metabolic 1.23 0.964 – 1.56 0.097 71 767 exclusion phecode
255.11 Cushing's syndrome Endocrine/metabolic 1.25 0.919 – 1.71 0.153 40 466 exclusion phecode
255.12 Hyperaldosteronism Endocrine/metabolic 1.13 0.787 – 1.63 0.505 32 296 exclusion phecode
255.2 Adrenal hypofunction Endocrine/metabolic 1.01 0.852 – 1.2 0.896 147 1442 exclusion phecode
255.21 Glucocorticoid deficiency Endocrine/metabolic 1.01 0.852 – 1.2 0.889 146 1438 exclusion phecode
256 Ovarian dysfunction Endocrine/metabolic 1.06 0.877 – 1.27 0.568 127 1088 exclusion phecode
256.4 Polycystic ovaries Endocrine/metabolic 0.991 0.815 – 1.21 0.929 111 958 exclusion phecode
257 Testicular dysfunction Endocrine/metabolic 1.17 0.895 – 1.53 0.248 58 568 exclusion phecode
257.1 Testicular hypofunction Endocrine/metabolic 1.18 0.889 – 1.56 0.256 54 538 exclusion phecode
258 Iatrogenic endocrine disorders Endocrine/metabolic 1.34 0.97 – 1.86 0.0753 41 379 exclusion phecode
259 Other endocrine disorders Endocrine/metabolic 1.08 0.825 – 1.41 0.578 55 588 exclusion phecode
260 Protein-calorie malnutrition Endocrine/metabolic 0.916 0.704 – 1.19 0.513 58 782 exclusion phecode
260.1 Cachexia Endocrine/metabolic 1.07 0.628 – 1.84 0.794 12 189 exclusion phecode
260.6 Anorexia Endocrine/metabolic 1.08 0.959 – 1.22 0.201 290 3133 exclusion phecode
261 Vitamin deficiency Endocrine/metabolic 1.12 1.02 – 1.24 0.024 425 4688 exclusion phecode
261.2 Vitamin B-complex deficiencies Endocrine/metabolic 1.17 1.02 – 1.34 0.0221 242 2875 exclusion phecode
261.4 Vitamin D deficiency Endocrine/metabolic 0.999 0.858 – 1.16 0.99 189 1804 exclusion phecode
261.41 Rickets or osteomalacia Endocrine/metabolic 1.29 0.931 – 1.8 0.125 37 297 exclusion phecode
262 Mineral deficiency NEC Endocrine/metabolic 1.03 0.837 – 1.27 0.761 100 959 exclusion phecode
269 Proteinuria Endocrine/metabolic 1.16 0.953 – 1.41 0.14 100 1298 exclusion phecode
270
Disorders of protein plasma/amino-acid
Disorders of protein plasma/amino-acid transport and metabolism
 Endocrine/metabolic 1.24 1 – 1.52 0.0484 103 1089 exclusion phecode
270.3 Disorders of plasma protein metabolism Endocrine/metabolic 1.24 0.994 – 1.54 0.0565 91 903 exclusion phecode
270.32 Paraproteinemia Endocrine/metabolic 1.12 0.857 – 1.46 0.408 61 659 exclusion phecode
270.33 Amyloidosis Endocrine/metabolic 1.23 0.891 – 1.7 0.208 44 412 exclusion phecode
270.35 Macroglobulinemia Endocrine/metabolic 1.35 0.914 – 1.99 0.132 34 268 exclusion phecode
271
Disorders of carbohydrate transport and
Disorders of carbohydrate transport and metabolism
 Endocrine/metabolic 0.929 0.717 – 1.2 0.578 65 618 exclusion phecode
271.3
Intestinal disaccharidase deficiencies and
Intestinal disaccharidase deficiencies and disaccharide malabsorption
 Endocrine/metabolic 0.918 0.693 – 1.22 0.555 55 538 exclusion phecode
272 Disorders of lipoid metabolism Endocrine/metabolic 1.07 1.05 – 1.1 5.45e-12 10844 91455 exclusion phecode
272.1 Hyperlipidemia Endocrine/metabolic 1.07 1.05 – 1.1 6.28e-12 10818 91373 exclusion phecode
272.11 Hypercholesterolemia Endocrine/metabolic 1.07 1.05 – 1.09 3.07e-10 10034 88404 exclusion phecode
272.12 Hyperglyceridemia Endocrine/metabolic 1.1 0.703 – 1.72 0.681 18 201 exclusion phecode
272.13 Mixed hyperlipidemia Endocrine/metabolic 1.16 0.865 – 1.57 0.317 47 617 exclusion phecode
272.9 Unspecified disorder of lipoid metabolism Endocrine/metabolic 1.02 0.791 – 1.32 0.876 61 761 exclusion phecode
274 Gout and other crystal arthropathies Endocrine/metabolic 1.2 1.13 – 1.27 1.07e-08 1106 13015 exclusion phecode
274.1 Gout Endocrine/metabolic 1.23 1.15 – 1.32 3.61e-09 903 10878 exclusion phecode
274.11 Gouty arthropathy Endocrine/metabolic 1.38 1.01 – 1.89 0.0449 44 394 exclusion phecode
274.2 Crystal arthropathies Endocrine/metabolic 1.1 0.957 – 1.26 0.184 226 2322 exclusion phecode
274.21 Chondrocalcinosis Endocrine/metabolic 1.09 0.942 – 1.26 0.247 198 2137 exclusion phecode
275 Disorders of mineral metabolism Endocrine/metabolic 1.05 0.971 – 1.13 0.223 701 7960 exclusion phecode
275.1 Disorders of iron metabolism Hematopoietic 1.15 0.999 – 1.32 0.0512 212 2352 exclusion phecode
275.3 Disorders of magnesium metabolism Endocrine/metabolic 0.961 0.799 – 1.16 0.671 120 1408 exclusion phecode
275.5 Disorders of calcium/phosphorus metabolism Endocrine/metabolic 1.03 0.933 – 1.15 0.523 403 4653 exclusion phecode
275.53 Disorders of phosphorus metabolism Endocrine/metabolic 1.13 0.868 – 1.48 0.362 60 669 exclusion phecode
276
Disorders of fluid, electrolyte, and acid-base
Disorders of fluid, electrolyte, and acid-base balance
 Endocrine/metabolic 1.04 1 – 1.09 0.0511 2361 27695 exclusion phecode
276.1 Electrolyte imbalance Endocrine/metabolic 1.02 0.964 – 1.08 0.498 1336 15500 exclusion phecode
276.11 Hyperosmolality and/or hypernatremia Endocrine/metabolic 0.819 0.643 – 1.04 0.105 77 907 exclusion phecode
276.12 Hyposmolality and/or hyponatremia Endocrine/metabolic 1.06 0.974 – 1.15 0.185 606 6930 exclusion phecode
276.13 Hyperpotassemia Endocrine/metabolic 1.09 0.967 – 1.23 0.156 297 3489 exclusion phecode
276.14 Hypopotassemia Endocrine/metabolic 0.953 0.869 – 1.05 0.305 476 5620 exclusion phecode
276.4 Acid-base balance disorder Endocrine/metabolic 1.07 0.96 – 1.2 0.214 326 4421 exclusion phecode
276.41 Acidosis Endocrine/metabolic 1.08 0.959 – 1.22 0.205 294 3993 exclusion phecode
276.42 Alkalosis Endocrine/metabolic 0.952 0.673 – 1.35 0.783 34 426 exclusion phecode
276.5 Hypovolemia Endocrine/metabolic 1.06 0.995 – 1.14 0.0686 939 10721 exclusion phecode
276.6 Fluid overload Endocrine/metabolic 1.06 0.894 – 1.25 0.52 147 1687 exclusion phecode
276.8 Polydipsia Endocrine/metabolic 1.2 0.889 – 1.62 0.234 47 531 exclusion phecode
277 Other disorders of metabolism Endocrine/metabolic 1.02 0.91 – 1.15 0.714 306 3440 exclusion phecode
277.4 Disorders of bilirubin excretion Endocrine/metabolic 1.12 0.953 – 1.32 0.165 163 1314 exclusion phecode
277.5 Other disorders of lipoid metabolism Endocrine/metabolic 1.22 0.97 – 1.55 0.0878 70 840 exclusion phecode
277.51 Lipoprotein disorders Endocrine/metabolic 1.18 0.664 – 2.1 0.573 11 196 exclusion phecode
278 Overweight, obesity and other hyperalimentation Endocrine/metabolic 1.21 1.17 – 1.25 1.6e-27 3679 42786 exclusion phecode
278.1 Obesity Endocrine/metabolic 1.21 1.17 – 1.25 2.42e-27 3617 42120 exclusion phecode
278.3 Localized adiposity Endocrine/metabolic 1.02 0.708 – 1.46 0.933 30 363 exclusion phecode
278.4 Abnormal weight gain Endocrine/metabolic 1.46 1 – 2.13 0.0473 27 286 exclusion phecode
279 Disorders involving the immune mechanism Endocrine/metabolic 0.948 0.77 – 1.17 0.618 92 948 exclusion phecode
279.1 Immunity deficiency Endocrine/metabolic 0.972 0.778 – 1.21 0.804 80 801 exclusion phecode
279.11 Deficiency of humoral immunity Endocrine/metabolic 0.86 0.652 – 1.13 0.283 50 536 exclusion phecode
279.7 Other immunological findings Endocrine/metabolic 1.32 1.06 – 1.64 0.0123 95 825 exclusion phecode
280 Iron deficiency anemias Hematopoietic 1.05 1.01 – 1.09 0.018 3027 30054 exclusion phecode
280.1
Iron deficiency anemias, unspecified or not due
Iron deficiency anemias, unspecified or not due to blood loss
 Hematopoietic 1.05 1.01 – 1.09 0.0116 2917 28847 exclusion phecode
280.2
Iron deficiency anemia secondary to blood loss
Iron deficiency anemia secondary to blood loss (chronic)
 Hematopoietic 1.02 0.875 – 1.18 0.823 184 1859 exclusion phecode
281 Other deficiency anemia Hematopoietic 1.14 1.03 – 1.26 0.015 404 4412 exclusion phecode
281.1 Megaloblastic anemia Hematopoietic 1.13 1.01 – 1.25 0.0262 391 4242 exclusion phecode
281.11 Pernicious anemia Hematopoietic 1.27 1.12 – 1.44 0.000211 280 2994 exclusion phecode
281.12 Other vitamin B12 deficiency anemia Hematopoietic 0.771 0.607 – 0.979 0.033 72 736 exclusion phecode
281.13 Folate-deficiency anemia Hematopoietic 1.12 0.869 – 1.45 0.373 59 656 exclusion phecode
281.9 Deficiency anemias Hematopoietic 0.897 0.569 – 1.41 0.639 19 199 exclusion phecode
282 Hereditary hemolytic anemias Hematopoietic 1.14 0.876 – 1.48 0.328 57 593 exclusion phecode
282.8 Other hemoglobinopathies Hematopoietic 0.898 0.576 – 1.4 0.637 19 214 exclusion phecode
282.9 Other hereditary hemolytic anemias Hematopoietic 1.17 0.835 – 1.63 0.367 34 354 exclusion phecode
283 Acquired hemolytic anemias Hematopoietic 1.18 0.896 – 1.57 0.234 54 525 exclusion phecode
283.1 Autoimmune hemolytic anemias Hematopoietic 1.31 0.967 – 1.78 0.0812 45 416 exclusion phecode
284 Aplastic anemia Hematopoietic 0.899 0.761 – 1.06 0.209 145 1611 exclusion phecode
285 Other anemias Hematopoietic 1.04 1.01 – 1.07 0.0129 4529 47293 exclusion phecode
285.1 Acute posthemorrhagic anemia Hematopoietic 0.988 0.812 – 1.2 0.903 109 1087 exclusion phecode
285.2 Anemia of chronic disease Hematopoietic 1.07 0.937 – 1.22 0.32 248 2696 exclusion phecode
285.22 Anemia in neoplastic disease Hematopoietic 1.05 0.886 – 1.24 0.583 160 1625 exclusion phecode
286 Coagulation defects Hematopoietic 1 0.895 – 1.12 0.971 335 3627 exclusion phecode
286.1 Congenital coagulation defects Hematopoietic 1.14 0.977 – 1.33 0.0953 176 1862 exclusion phecode
286.11 Von willebrand's disease Hematopoietic 1.22 0.862 – 1.72 0.264 39 380 exclusion phecode
286.12
Congenital deficiency of other clotting factors
Congenital deficiency of other clotting factors (including factor VII)
 Hematopoietic 1.16 0.957 – 1.4 0.132 113 1229 exclusion phecode
286.13 Congenital factor VIII disorder Hematopoietic 1.14 0.732 – 1.76 0.57 19 260 exclusion phecode
286.5
Hemorrhagic disorder due to intrinsic
Hemorrhagic disorder due to intrinsic circulating anticoagulants
 Hematopoietic 0.622 0.412 – 0.941 0.0245 25 325 exclusion phecode
286.7 Other and unspecified coagulation defects Hematopoietic 1.01 0.855 – 1.2 0.883 143 1531 exclusion phecode
287 Purpura and other hemorrhagic conditions Hematopoietic 0.976 0.897 – 1.06 0.581 595 6153 exclusion phecode
287.1 Spontaneous ecchymoses Hematopoietic 0.987 0.737 – 1.32 0.928 54 504 exclusion phecode
287.2 Allergic purpura Hematopoietic 0.843 0.532 – 1.34 0.469 20 195 exclusion phecode
287.3 Thrombocytopenia Hematopoietic 0.991 0.908 – 1.08 0.838 562 5764 exclusion phecode
287.31 Primary thrombocytopenia Hematopoietic 0.946 0.802 – 1.12 0.506 157 1605 exclusion phecode
287.32 Secondary thrombocytopenia Hematopoietic 0.574 0.378 – 0.872 0.00925 26 288 exclusion phecode
288 Diseases of white blood cells Hematopoietic 0.958 0.907 – 1.01 0.123 1422 14614 exclusion phecode
288.1 Decreased white blood cell count Hematopoietic 0.944 0.889 – 1 0.0563 1210 12307 exclusion phecode
288.11 Neutropenia Hematopoietic 0.945 0.891 – 1 0.0635 1214 12337 exclusion phecode
288.3 Eosinophilia Hematopoietic 0.832 0.575 – 1.2 0.33 29 270 exclusion phecode
289 Other diseases of blood and blood-forming organs Hematopoietic 1.12 1 – 1.26 0.0503 304 3229 exclusion phecode
289.3
Personal history of diseases of blood and
Personal history of diseases of blood and blood-forming organs
 Hematopoietic 1.03 0.854 – 1.23 0.783 119 1113 exclusion phecode
289.4 Lymphadenitis Hematopoietic 1.07 0.998 – 1.15 0.0564 873 10116 exclusion phecode
289.5 Diseases of spleen Hematopoietic 0.984 0.841 – 1.15 0.838 172 1935 exclusion phecode
289.8 Polycythemia, secondary Hematopoietic 1.3 1.03 – 1.63 0.0272 75 1043 exclusion phecode
289.9 Abnormality of red blood cells Hematopoietic 1.22 0.823 – 1.8 0.325 25 325 exclusion phecode
290
Delirium dementia and amnestic and other
Delirium dementia and amnestic and other cognitive disorders
 Mental Disorders 1.05 0.965 – 1.14 0.254 602 6883 exclusion phecode
290.1 Dementias Mental Disorders 1.09 0.98 – 1.22 0.111 345 3512 exclusion phecode
290.11 Alzheimer's disease Mental Disorders 1.08 0.908 – 1.28 0.395 146 1551 exclusion phecode
290.16 Vascular dementia Mental Disorders 1.2 0.931 – 1.56 0.157 63 659 exclusion phecode
290.2 Delirium due to conditions classified elsewhere Mental Disorders 0.975 0.842 – 1.13 0.732 188 2302 exclusion phecode
290.3
Other persistent mental disorders due to
Other persistent mental disorders due to conditions classified elsewhere
 Mental Disorders 1.44 0.854 – 2.44 0.171 14 277 exclusion phecode
291
Other specified nonpsychotic and/or transient
Other specified nonpsychotic and/or transient mental disorders
 Mental Disorders 1.17 1.03 – 1.32 0.0129 282 3225 exclusion phecode
291.1
Transient mental disorders due to conditions
Transient mental disorders due to conditions classified elsewhere
 Mental Disorders 0.923 0.673 – 1.27 0.617 41 551 exclusion phecode
291.4
Specific nonpsychotic mental disorders due to
Specific nonpsychotic mental disorders due to brain damage
 Mental Disorders 1.1 0.895 – 1.36 0.358 95 1098 exclusion phecode
291.8 Alteration of consciousness Mental Disorders 1.27 1.07 – 1.49 0.00493 153 1638 exclusion phecode
292 Neurological disorders Mental Disorders 1.02 0.97 – 1.08 0.407 1554 17349 exclusion phecode
292.1 Aphasia/speech disturbance Mental Disorders 1 0.915 – 1.1 0.935 502 5692 exclusion phecode
292.2 Mild cognitive impairment Mental Disorders 1.15 0.893 – 1.47 0.286 64 701 exclusion phecode
292.3 Memory loss Mental Disorders 1.05 0.922 – 1.19 0.471 254 2646 exclusion phecode
292.4 Altered mental status Mental Disorders 1.03 0.949 – 1.11 0.514 711 7984 exclusion phecode
292.6 Hallucinations Mental Disorders 0.929 0.769 – 1.12 0.446 115 1169 exclusion phecode
293 Symptoms involving head and neck Mental Disorders 1.15 1.06 – 1.25 0.00068 641 7752 exclusion phecode
293.1
Swelling, mass, or lump in head and neck
Swelling, mass, or lump in head and neck [Space-occupying lesion, intracranial NOS]
 Mental Disorders 0.998 0.89 – 1.12 0.975 324 3545 exclusion phecode
295 Schizophrenia and other psychotic disorders Mental Disorders 1.01 0.883 – 1.15 0.899 237 3517 exclusion phecode
295.1 Schizophrenia Mental Disorders 0.906 0.766 – 1.07 0.253 150 2342 exclusion phecode
295.2 Paranoid disorders Mental Disorders 1.22 0.935 – 1.59 0.144 61 747 exclusion phecode
295.3 Psychosis Mental Disorders 0.97 0.731 – 1.29 0.833 56 734 exclusion phecode
296 Mood disorders Mental Disorders 1.11 1.08 – 1.15 1.68e-10 4031 53381 exclusion phecode
296.1 Bipolar Mental Disorders 1.03 0.918 – 1.15 0.629 318 4506 exclusion phecode
296.2 Depression Mental Disorders 1.12 1.09 – 1.16 5.39e-12 3845 50779 exclusion phecode
296.22 Major depressive disorder Mental Disorders 1.1 0.918 – 1.32 0.302 130 1508 exclusion phecode
297.2 Suicide or self-inflicted injury Mental Disorders 1.11 0.887 – 1.39 0.359 81 1358 exclusion phecode
300 Anxiety disorders Mental Disorders 1.06 1.02 – 1.1 0.00658 2456 29389 exclusion phecode
300.1 Anxiety disorder Mental Disorders 1.07 1.03 – 1.12 0.00147 2291 27155 exclusion phecode
300.11 Generalized anxiety disorder Mental Disorders 1 0.776 – 1.29 0.99 67 648 exclusion phecode
300.12 Agorophobia, social phobia, and panic disorder Mental Disorders 1.1 0.971 – 1.25 0.132 255 3058 exclusion phecode
300.13 Phobia Mental Disorders 1.08 0.922 – 1.25 0.354 180 2181 exclusion phecode
300.3 Obsessive-compulsive disorders Mental Disorders 0.964 0.744 – 1.25 0.782 57 578 exclusion phecode
300.4 Dysthymic disorder Mental Disorders 1.05 0.667 – 1.64 0.842 19 217 exclusion phecode
300.8 Acute reaction to stress Mental Disorders 0.907 0.668 – 1.23 0.532 40 531 exclusion phecode
300.9 Posttraumatic stress disorder Mental Disorders 0.862 0.606 – 1.23 0.409 32 489 exclusion phecode
301 Personality disorders Mental Disorders 1.05 0.854 – 1.3 0.632 95 1468 exclusion phecode
301.2 Antisocial/borderline personality disorder Mental Disorders 0.956 0.677 – 1.35 0.796 35 523 exclusion phecode
302 Sexual and gender identity disorders Mental Disorders 1.1 0.864 – 1.41 0.43 68 1069 exclusion phecode
303 Psychogenic and somatoform disorders Mental Disorders 1.1 0.95 – 1.28 0.196 188 1997 exclusion phecode
303.3 Psychogenic disorder Mental Disorders 1.06 0.887 – 1.27 0.521 134 1503 exclusion phecode
303.4 Somatoform disorder Mental Disorders 1.22 0.932 – 1.6 0.148 54 542 exclusion phecode
304 Adjustment reaction Mental Disorders 1.5 1.22 – 1.83 9.99e-05 104 1310 exclusion phecode
305.2 Eating disorder Mental Disorders 0.941 0.691 – 1.28 0.701 47 403 exclusion phecode
306 Other mental disorder Mental Disorders 1.15 1.09 – 1.22 2.35e-07 1326 94770 exclusion phecode
306.9 Tension headache Mental Disorders 1.06 0.882 – 1.27 0.548 119 1378 exclusion phecode
313 Pervasive developmental disorders Mental Disorders 1.36 0.952 – 1.94 0.0912 31 280 exclusion phecode
313.3 Autism Mental Disorders 1.35 0.894 – 2.04 0.154 22 193 exclusion phecode
315 Develomental delays and disorders Mental Disorders 1.23 1.01 – 1.51 0.0416 108 1311 exclusion phecode
315.1 Learning disorder Mental Disorders 1.34 1.07 – 1.68 0.0102 79 629 exclusion phecode
315.2 Speech and language disorder Mental Disorders 0.79 0.482 – 1.3 0.351 19 302 exclusion phecode
316 Substance addiction and disorders Mental Disorders 1.19 1.11 – 1.26 8.71e-08 1035 21290 exclusion phecode
316.1 Polyneuropathy due to drugs Mental Disorders 0.818 0.528 – 1.27 0.37 20 230 exclusion phecode
317 Alcohol-related disorders Mental Disorders 1.14 1.1 – 1.18 5.41e-12 3092 50473 exclusion phecode
317.1 Alcoholism Mental Disorders 1.12 1.08 – 1.17 7.03e-08 2291 35291 exclusion phecode
317.11 Alcoholic liver damage Mental Disorders 1.17 1.01 – 1.36 0.0397 180 3312 exclusion phecode
318 Tobacco use disorder Mental Disorders 1.11 1.02 – 1.21 0.0166 543 76332 exclusion phecode
320 Meningitis Neurological 1.09 0.928 – 1.28 0.293 178 1778 exclusion phecode
323 Encephalitis Neurological 1.09 0.905 – 1.32 0.359 125 1352 exclusion phecode
323.2 Acute (transverse) myelitis Neurological 1 0.679 – 1.49 0.98 27 303 exclusion phecode
324 Other CNS infection and poliomyelitis Neurological 0.9 0.738 – 1.1 0.299 107 1158 exclusion phecode
327 Sleep disorders Neurological 1.17 1.06 – 1.3 0.00289 377 4381 exclusion phecode
327.3 Sleep apnea Neurological 1.17 1.11 – 1.24 2.26e-08 1390 16291 exclusion phecode
327.4 Insomnia Neurological 1.05 0.795 – 1.39 0.723 52 618 exclusion phecode
327.41 Organic or persistent insomnia Neurological 1.07 0.794 – 1.44 0.657 43 524 exclusion phecode
331 Other cerebral degenerations Neurological 1.14 1.03 – 1.26 0.00939 407 4192 exclusion phecode
331.1 Hydrocephalus Neurological 1.21 1.04 – 1.4 0.0149 179 1902 exclusion phecode
331.9 Cerebral degeneration, unspecified Neurological 1.05 0.889 – 1.24 0.563 147 1548 exclusion phecode
332 Parkinson's disease Neurological 1.04 0.946 – 1.15 0.401 483 3973 exclusion phecode
333
Extrapyramidal disease and abnormal movement
Extrapyramidal disease and abnormal movement disorders
 Neurological 1.02 0.909 – 1.14 0.779 341 3533 exclusion phecode
333.1 Essential tremor Neurological 0.911 0.718 – 1.16 0.443 76 871 exclusion phecode
333.2 Myoclonus Neurological 1.03 0.728 – 1.46 0.869 36 379 exclusion phecode
333.4 Torsion dystonia Neurological 0.939 0.776 – 1.14 0.515 111 1006 exclusion phecode
334 Degenerative disease of the spinal cord Neurological 1.07 0.986 – 1.17 0.103 593 6753 exclusion phecode
334.1 Spinocerebellar disease Neurological 0.968 0.717 – 1.31 0.831 50 423 exclusion phecode
334.2 Anterior horn cell disease Neurological 0.946 0.769 – 1.16 0.597 96 860 exclusion phecode
335 Multiple sclerosis Neurological 0.981 0.891 – 1.08 0.688 473 5596 exclusion phecode
337 Disorders of the autonomic nervous system Neurological 0.933 0.762 – 1.14 0.508 103 1004 exclusion phecode
337.1 Peripheral autonomic neuropathy Neurological 1.06 0.738 – 1.53 0.741 30 269 exclusion phecode
338 Pain Neurological 1.14 1.01 – 1.3 0.0381 260 3028 exclusion phecode
338.1 Acute pain Neurological 1.13 0.953 – 1.35 0.158 143 1507 exclusion phecode
338.2 Chronic pain Neurological 1.13 0.936 – 1.36 0.205 118 1561 exclusion phecode
339 Other headache syndromes Neurological 1.09 1.05 – 1.13 4.77e-06 2976 31811 exclusion phecode
340 Migraine Neurological 1.07 1.01 – 1.13 0.0311 1207 11984 exclusion phecode
340.1 Migrain with aura Neurological 1.16 0.939 – 1.43 0.169 90 905 exclusion phecode
341
Other demyelinating diseases of central nervous
Other demyelinating diseases of central nervous system
 Neurological 1.01 0.793 – 1.28 0.948 74 1089 exclusion phecode
342 Hemiplegia Neurological 1.08 0.987 – 1.19 0.0914 471 5556 exclusion phecode
343 Infantile cerebral palsy Neurological 1.19 0.939 – 1.51 0.149 79 597 exclusion phecode
344 Other paralytic syndromes Neurological 1.06 0.92 – 1.22 0.429 213 2545 exclusion phecode
345 Epilepsy, recurrent seizures, convulsions Neurological 1.08 1.03 – 1.13 0.00164 1870 19539 exclusion phecode
345.1 Epilepsy Neurological 1.12 1 – 1.25 0.0472 340 3384 exclusion phecode
345.11 Generalized convulsive epilepsy Neurological 1.06 0.904 – 1.25 0.464 167 1721 exclusion phecode
345.12 Partial epilepsy Neurological 1.03 0.851 – 1.24 0.767 111 1117 exclusion phecode
345.3 Convulsions Neurological 1.01 0.941 – 1.09 0.741 798 8679 exclusion phecode
346.1
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of skull and head
 Neurological 1.49 1.11 – 1.99 0.00702 48 552 exclusion phecode
348 Other conditions of brain Neurological 1.12 0.995 – 1.27 0.0601 278 3018 exclusion phecode
348.2 Cerebral edema and compression of brain Neurological 1.24 1.01 – 1.53 0.0379 103 1061 exclusion phecode
348.4 Cerebral cysts Neurological 0.971 0.751 – 1.26 0.822 61 511 exclusion phecode
348.7 Coma Neurological 1.08 0.907 – 1.3 0.374 127 1360 exclusion phecode
348.8 Encephalopathy, not elsewhere classified Neurological 1.25 0.996 – 1.57 0.0547 77 964 exclusion phecode
348.9 Other conditions of brain, NOS Neurological 1.11 0.932 – 1.32 0.247 128 1494 exclusion phecode
349
Other and unspecified disorders of the nervous
Other and unspecified disorders of the nervous system
 Neurological 1.3 1.08 – 1.57 0.00528 126 1335 exclusion phecode
350 Abnormal movement Neurological 1.1 1.03 – 1.18 0.00614 951 10155 exclusion phecode
350.1 Abnormal involuntary movements Neurological 1.16 1.03 – 1.3 0.0118 339 3363 exclusion phecode
350.2 Abnormality of gait Neurological 1.05 0.959 – 1.14 0.299 552 5987 exclusion phecode
350.3 Lack of coordination Neurological 1.06 0.878 – 1.27 0.563 126 1349 exclusion phecode
350.6 Disturbances of sensation of smell and taste Neurological 1.02 0.664 – 1.57 0.929 23 204 exclusion phecode
351 Other peripheral nerve disorders Neurological 1.12 1.09 – 1.15 5.67e-13 4529 50460 exclusion phecode
352 Disorders of other cranial nerves Neurological 1.09 0.992 – 1.19 0.0729 515 5425 exclusion phecode
352.1 Trigeminal nerve disorders [CN5] Neurological 1.03 0.88 – 1.2 0.72 165 1900 exclusion phecode
352.2 Facial nerve disorders [CN7] Neurological 1.15 1.03 – 1.29 0.0161 338 3409 exclusion phecode
353 Nerve root and plexus disorders Neurological 1.03 0.932 – 1.15 0.524 374 4298 exclusion phecode
353.1 Nerve plexus lesions Neurological 0.889 0.672 – 1.18 0.412 48 470 exclusion phecode
353.2 Nerve root lesions Neurological 0.83 0.534 – 1.29 0.41 21 212 exclusion phecode
356 Hereditary and idiopathic peripheral neuropathy Neurological 1.02 0.767 – 1.36 0.887 50 552 exclusion phecode
357 Inflammatory and toxic neuropathy Neurological 1.02 0.932 – 1.13 0.621 482 5051 exclusion phecode
358 Myoneural disorders Neurological 0.845 0.665 – 1.07 0.169 77 740 exclusion phecode
358.1 Myasthenia gravis Neurological 0.821 0.643 – 1.05 0.113 73 689 exclusion phecode
359 Muscular dystrophies and other myopathies Neurological 1.05 0.905 – 1.22 0.513 178 1815 exclusion phecode
359.1 Muscular dystrophies Neurological 1.06 0.804 – 1.41 0.663 54 493 exclusion phecode
359.2 Myopathy Neurological 1.06 0.893 – 1.26 0.492 133 1419 exclusion phecode
360 Disorders of the globe Sense Organs 0.995 0.827 – 1.2 0.954 125 1312 exclusion phecode
360.2 Progressive myopia Sense Organs 0.939 0.762 – 1.16 0.552 92 948 exclusion phecode
361 Retinal detachments and defects Sense Organs 0.938 0.884 – 0.995 0.0321 1240 11543 exclusion phecode
361.1 Retinal detachment with retinal defect Sense Organs 0.979 0.895 – 1.07 0.639 520 4919 exclusion phecode
361.2 Retinoschisis and retinal cysts Sense Organs 0.809 0.573 – 1.14 0.231 37 273 exclusion phecode
362 Other retinal disorders Sense Organs 1.05 0.989 – 1.11 0.117 1399 14316 exclusion phecode
362.2
Degeneration of macula and posterior pole of
Degeneration of macula and posterior pole of retina
 Sense Organs 1.07 0.993 – 1.15 0.0773 801 8314 exclusion phecode
362.29 Macular degeneration (senile) of retina NOS Sense Organs 1.07 0.993 – 1.15 0.0773 801 8297 exclusion phecode
362.3 Other nondiabetic retinopathy Sense Organs 1.02 0.783 – 1.34 0.868 55 574 exclusion phecode
362.31 Separation of retinal layers Sense Organs 0.936 0.66 – 1.33 0.708 33 368 exclusion phecode
362.4 Retinal vascular changes and abnomalities Sense Organs 0.981 0.871 – 1.1 0.75 304 3069 exclusion phecode
362.6 Peripheral retinal degenerations Sense Organs 1.12 0.873 – 1.44 0.373 71 655 exclusion phecode
362.7 Hereditary retinal dystrophies Sense Organs 0.938 0.688 – 1.28 0.689 41 323 exclusion phecode
362.8 Retinal hemorrhage/ischemia Sense Organs 1.05 0.756 – 1.47 0.757 38 420 exclusion phecode
363
Chorioretinal inflammations, scars, and other
Chorioretinal inflammations, scars, and other disorders of choroid
 Sense Organs 0.901 0.716 – 1.13 0.371 74 674 exclusion phecode
363.3 Chorioretinal scars Sense Organs 0.846 0.596 – 1.2 0.351 31 266 exclusion phecode
364 Corneal opacity and other disorders of cornea Sense Organs 1.04 0.917 – 1.18 0.538 255 2447 exclusion phecode
364.1 Corneal opacity Sense Organs 0.851 0.595 – 1.22 0.374 32 352 exclusion phecode
364.2 Corneal edema Sense Organs 1.4 0.934 – 2.1 0.103 28 290 exclusion phecode
364.4 Corneal degenerations Sense Organs 0.839 0.678 – 1.04 0.106 89 747 exclusion phecode
364.41 Keratoconus Sense Organs 0.719 0.522 – 0.992 0.0447 45 320 exclusion phecode
364.5 Corneal dystrophy Sense Organs 1.09 0.864 – 1.37 0.468 73 820 exclusion phecode
364.9 Cornea replaced by transplant Sense Organs 1.19 0.848 – 1.68 0.31 35 406 exclusion phecode
365 Glaucoma Sense Organs 1.02 0.972 – 1.08 0.387 1655 16267 exclusion phecode
365.1 Open-angle glaucoma Sense Organs 0.94 0.844 – 1.05 0.259 383 3690 exclusion phecode
365.11 Primary open angle glaucoma Sense Organs 0.93 0.834 – 1.04 0.19 379 3678 exclusion phecode
365.2 Primary angle-closure glaucoma Sense Organs 1.13 1 – 1.28 0.0436 286 2776 exclusion phecode
366 Cataract Sense Organs 1.04 1.01 – 1.06 0.00297 7091 63159 exclusion phecode
366.1 Nonsenile Cataract Sense Organs 1.21 0.841 – 1.75 0.302 30 277 exclusion phecode
366.2 Senile cataract Sense Organs 1.05 1.01 – 1.09 0.00815 2876 31149 exclusion phecode
366.3 Traumatic cataract Sense Organs 0.782 0.559 – 1.1 0.154 34 384 exclusion phecode
367
Disorders of refraction and accommodation
Disorders of refraction and accommodation; blindness and low vision
 Sense Organs 1.05 0.977 – 1.12 0.195 889 9161 exclusion phecode
367.1 Myopia Sense Organs 0.998 0.906 – 1.1 0.972 461 4745 exclusion phecode
367.2 Astigmatism Sense Organs 1.09 0.875 – 1.36 0.446 84 737 exclusion phecode
367.8 Hypermetropia Sense Organs 1.41 1.13 – 1.75 0.00214 91 954 exclusion phecode
367.9 Blindness and low vision Sense Organs 1.04 0.916 – 1.18 0.534 256 2714 exclusion phecode
368 Visual disturbances Sense Organs 1.05 0.991 – 1.12 0.092 1102 11462 exclusion phecode
368.1 Amblyopia Sense Organs 1.08 0.936 – 1.25 0.283 198 1945 exclusion phecode
368.2 Diplopia and disorders of binocular vision Sense Organs 1.04 0.919 – 1.18 0.525 265 2793 exclusion phecode
368.3 Anisometropia Sense Organs 0.915 0.693 – 1.21 0.534 56 554 exclusion phecode
368.4 Visual field defects Sense Organs 1.04 0.848 – 1.27 0.728 107 1266 exclusion phecode
368.9 Subjective visual disturbances Sense Organs 1.2 1.06 – 1.37 0.00521 238 2509 exclusion phecode
369 Infection of the eye Sense Organs 0.966 0.841 – 1.11 0.627 218 2150 exclusion phecode
369.2 Eye infection, viral Sense Organs 0.788 0.585 – 1.06 0.119 47 484 exclusion phecode
369.5 Conjunctivitis, infectious Sense Organs 0.882 0.705 – 1.1 0.27 82 811 exclusion phecode
370 Keratitis Sense Organs 1.11 0.917 – 1.36 0.276 110 1157 exclusion phecode
370.1 Corneal ulcer Sense Organs 1.03 0.786 – 1.34 0.854 54 553 exclusion phecode
371 Inflammation of the eye Sense Organs 1.02 0.961 – 1.08 0.516 1181 11912 exclusion phecode
371.1 Uveitis, noninfectious or NOS Sense Organs 0.918 0.784 – 1.07 0.285 167 1880 exclusion phecode
371.3 Inflammation of eyelids Sense Organs 1.03 0.967 – 1.1 0.337 948 9181 exclusion phecode
372 Disorders of conjunctiva Sense Organs 1.13 0.997 – 1.28 0.0558 280 2921 exclusion phecode
374 Other disorders of eyelids Sense Organs 1.05 1 – 1.1 0.0331 2042 21978 exclusion phecode
374.1 Ectropion or entropion Sense Organs 1.04 0.931 – 1.15 0.51 358 3802 exclusion phecode
374.3 Ptosis of eyelid Sense Organs 1.08 1 – 1.17 0.0506 689 7044 exclusion phecode
375 Disorders of lacrimal system Sense Organs 1.08 1 – 1.15 0.0368 887 8748 exclusion phecode
375.2 Epiphora Sense Organs 1.07 0.961 – 1.2 0.207 354 3495 exclusion phecode
376 Disorders of the orbit Sense Organs 1.17 0.823 – 1.67 0.379 36 334 exclusion phecode
377 Disorders of optic nerve and visual pathways Sense Organs 1.12 0.95 – 1.33 0.174 152 1460 exclusion phecode
377.1 Optic atrophy Sense Organs 1.06 0.701 – 1.59 0.791 25 213 exclusion phecode
377.3 Optic neuritis/neuropathy Sense Organs 0.989 0.743 – 1.32 0.94 55 534 exclusion phecode
378
Strabismus and other disorders of binocular eye
Strabismus and other disorders of binocular eye movements
 Sense Organs 1.02 0.937 – 1.12 0.608 556 5375 exclusion phecode
378.1 Strabismus (not specified as paralytic) Sense Organs 1.03 0.924 – 1.15 0.583 364 3499 exclusion phecode
378.2 Nystagmus and other irregular eye movements Sense Organs 1.17 0.938 – 1.45 0.166 90 809 exclusion phecode
378.5 Paralytic strabismus Sense Organs 0.919 0.75 – 1.12 0.41 101 1042 exclusion phecode
379 Other disorders of eye Sense Organs 1.01 0.958 – 1.07 0.63 1298 14063 exclusion phecode
379.2 Disorders of vitreous body Sense Organs 0.988 0.901 – 1.08 0.801 505 5064 exclusion phecode
379.3 Aphakia and other disorders of lens Sense Organs 1.02 0.94 – 1.11 0.607 600 6877 exclusion phecode
379.4 Anomalies of pupillary function Sense Organs 1.19 0.837 – 1.7 0.332 31 283 exclusion phecode
379.5 Disorders of iris and ciliary body Sense Organs 1.09 0.929 – 1.28 0.288 152 1533 exclusion phecode
379.9 Pain, swelling or discharge of eye Sense Organs 0.933 0.722 – 1.21 0.595 62 686 exclusion phecode
380 Disorders of external ear Sense Organs 1.14 0.988 – 1.32 0.0717 211 2485 exclusion phecode
380.1 Otitis externa Sense Organs 1.16 0.991 – 1.36 0.0639 172 2105 exclusion phecode
380.4 Impacted cerumen Sense Organs 1.05 0.881 – 1.25 0.596 135 1381 exclusion phecode
381 Otitis media and Eustachian tube disorders Sense Organs 1.05 0.978 – 1.14 0.165 759 8237 exclusion phecode
381.1 Otitis media Sense Organs 1.04 0.958 – 1.13 0.353 623 6719 exclusion phecode
381.11 Suppurative and unspecified otitis media Sense Organs 1.02 0.905 – 1.15 0.751 301 3285 exclusion phecode
381.2 Eustachian tube disorders Sense Organs 1.18 0.923 – 1.51 0.186 70 785 exclusion phecode
381.3 Mastoiditis & related conditions Sense Organs 0.938 0.731 – 1.2 0.617 70 672 exclusion phecode
381.9 Otorrhea Sense Organs 1.17 0.937 – 1.46 0.166 83 1088 exclusion phecode
382 Otalgia Sense Organs 1.03 0.856 – 1.24 0.74 122 1199 exclusion phecode
383 Otosclerosis Sense Organs 0.874 0.728 – 1.05 0.15 127 1244 exclusion phecode
384 Other disorders of tympanic membrane Sense Organs 1.16 1.06 – 1.28 0.00196 450 5009 exclusion phecode
384.4 Perforation of tympanic membrane Sense Organs 1.12 1.01 – 1.25 0.0336 367 3990 exclusion phecode
385 Other disorders of middle ear and mastoid Sense Organs 1.01 0.889 – 1.14 0.924 270 2943 exclusion phecode
385.3 Cholesteatoma Sense Organs 0.964 0.837 – 1.11 0.618 207 2223 exclusion phecode
385.5
Tympanosclerosis and middle ear disease related
Tympanosclerosis and middle ear disease related to otitis media
 Sense Organs 1.12 0.907 – 1.39 0.286 92 943 exclusion phecode
386
Vertiginous syndromes and other disorders of
Vertiginous syndromes and other disorders of vestibular system
 Sense Organs 1.1 1.02 – 1.19 0.0126 714 6740 exclusion phecode
386.1 Meniere's disease Sense Organs 1.04 0.905 – 1.19 0.599 239 2248 exclusion phecode
386.2 Peripheral or central vertigo Sense Organs 1.13 0.955 – 1.34 0.155 156 1392 exclusion phecode
386.3 Labyrinthitis Sense Organs 1.15 1.03 – 1.29 0.0167 329 3014 exclusion phecode
386.9
Dizziness and giddiness (Light-headedness and
Dizziness and giddiness (Light-headedness and vertigo)
 Sense Organs 1.08 1.03 – 1.14 0.00169 1754 17576 exclusion phecode
388 Other disorders of ear Sense Organs 1.09 0.865 – 1.37 0.474 78 773 exclusion phecode
389 Hearing loss Sense Organs 1.06 1 – 1.11 0.0481 1483 15685 exclusion phecode
389.1 Sensorineural hearing loss Sense Organs 1.01 0.866 – 1.18 0.907 166 1729 exclusion phecode
389.2 Conductive hearing loss Sense Organs 1.08 0.914 – 1.26 0.382 168 1784 exclusion phecode
389.4 Tinnitus Sense Organs 0.976 0.841 – 1.13 0.75 193 1905 exclusion phecode
394 Rheumatic disease of the heart valves Circulatory System 1.1 1.04 – 1.15 0.000401 1636 17815 exclusion phecode
394.2 Mitral valve disease Circulatory System 1.08 1.01 – 1.15 0.0163 1030 10947 exclusion phecode
394.3 Aortic valve disease Circulatory System 1.08 0.972 – 1.19 0.157 412 4574 exclusion phecode
394.7 Disease of tricuspid valve Circulatory System 1.15 1.03 – 1.28 0.0133 358 3824 exclusion phecode
395 Heart valve disorders Circulatory System 1.08 1.02 – 1.14 0.00461 1406 15276 exclusion phecode
395.1 Nonrheumatic mitral valve disorders Circulatory System 1.08 1.01 – 1.16 0.0165 991 10561 exclusion phecode
395.2 Nonrheumatic aortic valve disorders Circulatory System 1.51 1.21 – 1.89 0.000312 82 972 exclusion phecode
395.3 Nonrheumatic tricuspid valve disorders Circulatory System 1.06 0.767 – 1.46 0.727 41 394 exclusion phecode
395.4 Nonrheumatic pulmonary valve disorders Circulatory System 1.48 1.04 – 2.1 0.0302 32 348 exclusion phecode
395.6 Heart valve replaced Circulatory System 0.994 0.905 – 1.09 0.905 476 5286 exclusion phecode
396 Abnormal heart sounds Circulatory System 1.06 0.962 – 1.18 0.228 440 4312 exclusion phecode
401 Hypertension Circulatory System 1.08 1.07 – 1.1 1.48e-28 25518 107621 exclusion phecode
401.1 Essential hypertension Circulatory System 1.08 1.07 – 1.1 3.22e-28 25453 107522 exclusion phecode
401.2 Hypertensive heart and/or renal disease Circulatory System 1.13 1.04 – 1.23 0.00538 570 7090 exclusion phecode
401.21 Hypertensive heart disease Circulatory System 1.26 1.03 – 1.54 0.0258 96 1359 exclusion phecode
401.22 Hypertensive chronic kidney disease Circulatory System 1.09 0.99 – 1.19 0.0802 477 5802 exclusion phecode
401.3 Other hypertensive complications Circulatory System 1.87 1.31 – 2.68 0.000581 35 553 exclusion phecode
402
Elevated blood pressure reading without
Elevated blood pressure reading without diagnosis of hypertension
 Circulatory System 1.06 0.971 – 1.16 0.196 552 5712 exclusion phecode
411 Ischemic Heart Disease Circulatory System 1.07 1.04 – 1.09 8.4e-09 9188 80944 exclusion phecode
411.1 Unstable angina (intermediate coronary syndrome) Circulatory System 1.11 1.05 – 1.17 0.000214 1439 19093 exclusion phecode
411.2 Myocardial infarction Circulatory System 1.06 1.02 – 1.1 0.00215 3094 40443 exclusion phecode
411.3 Angina pectoris Circulatory System 1.09 1.06 – 1.12 3.44e-08 4586 53391 exclusion phecode
411.4 Coronary atherosclerosis Circulatory System 1.06 1.03 – 1.09 4.43e-05 5639 57091 exclusion phecode
411.41 Aneurysm and dissection of heart Circulatory System 1.06 0.937 – 1.21 0.341 271 2640 exclusion phecode
411.8
Other chronic ischemic heart disease
Other chronic ischemic heart disease, unspecified
 Circulatory System 1.08 1.05 – 1.12 3.03e-06 4088 48138 exclusion phecode
411.9
Other acute and subacute forms of ischemic
Other acute and subacute forms of ischemic heart disease
 Circulatory System 1.03 0.92 – 1.15 0.639 341 4450 exclusion phecode
414 Other forms of chronic heart disease Circulatory System 1.04 0.945 – 1.14 0.446 500 6547 exclusion phecode
414.2 ASCVD Circulatory System 1.62 0.948 – 2.76 0.0775 12 267 exclusion phecode
415 Pulmonary heart disease Circulatory System 1.04 0.988 – 1.09 0.137 1600 16666 exclusion phecode
415.11 Pulmonary embolism and infarction, acute Circulatory System 0.542 0.369 – 0.796 0.00179 29 290 exclusion phecode
415.2 Chronic pulmonary heart disease Circulatory System 0.982 0.844 – 1.14 0.812 177 2189 exclusion phecode
415.21 Primary pulmonary hypertension Circulatory System 1.01 0.85 – 1.2 0.922 139 1655 exclusion phecode
416 Cardiomegaly Circulatory System 1.04 0.971 – 1.12 0.252 870 9548 exclusion phecode
418 Nonspecific chest pain Circulatory System 1.08 1.05 – 1.1 3.97e-12 10113 105402 exclusion phecode
418.1 Precordial pain Circulatory System 1.11 1.05 – 1.17 0.000471 1305 13885 exclusion phecode
420 Carditis Circulatory System 0.968 0.896 – 1.05 0.421 704 7743 exclusion phecode
420.1 Myocarditis Circulatory System 1.18 0.859 – 1.63 0.304 37 461 exclusion phecode
420.2 Pericarditis Circulatory System 0.945 0.854 – 1.05 0.276 421 4832 exclusion phecode
420.21 Acute pericarditis Circulatory System 0.946 0.742 – 1.21 0.651 69 832 exclusion phecode
420.22 Chronic pericarditis Circulatory System 0.903 0.658 – 1.24 0.529 37 427 exclusion phecode
420.3 Endocarditis Circulatory System 0.996 0.878 – 1.13 0.956 266 2703 exclusion phecode
425 Cardiomyopathy Circulatory System 1.1 0.998 – 1.21 0.0549 454 4582 exclusion phecode
425.1 Primary/intrinsic cardiomyopathies Circulatory System 1.12 1.01 – 1.23 0.0297 447 4465 exclusion phecode
425.11 Hypertrophic obstructive cardiomyopathy Circulatory System 1.02 0.782 – 1.34 0.866 56 504 exclusion phecode
425.12 Other hypertrophic cardiomyopathy Circulatory System 1.24 0.936 – 1.65 0.132 59 626 exclusion phecode
425.8 Other cardiomyopathy Circulatory System 0.752 0.44 – 1.28 0.297 15 186 exclusion phecode
426 Cardiac conduction disorders Circulatory System 1.04 0.997 – 1.09 0.0687 2239 24828 exclusion phecode
426.2 Atrioventricular [AV] block Circulatory System 1.09 1 – 1.18 0.0392 664 7420 exclusion phecode
426.21 First degree AV block Circulatory System 1.08 0.96 – 1.21 0.21 320 3427 exclusion phecode
426.23 Second degree AV block Circulatory System 1.03 0.87 – 1.22 0.74 148 1550 exclusion phecode
426.24 Atrioventricular block, complete Circulatory System 1.11 0.945 – 1.29 0.211 170 2039 exclusion phecode
426.25 Other heart block Circulatory System 0.992 0.724 – 1.36 0.96 41 453 exclusion phecode
426.3 Bundle branch block Circulatory System 1.01 0.951 – 1.08 0.684 1083 12204 exclusion phecode
426.31 Right bundle branch block Circulatory System 1.01 0.921 – 1.11 0.802 488 5383 exclusion phecode
426.32 Left bundle branch block Circulatory System 1.01 0.922 – 1.1 0.905 564 6503 exclusion phecode
426.4 Anomalous atrioventricular excitation Circulatory System 1.12 0.889 – 1.4 0.343 80 928 exclusion phecode
426.8 Other cardiac conduction disorders Circulatory System 0.977 0.626 – 1.53 0.919 19 244 exclusion phecode
426.9 Cardiac pacemaker/device in situ Circulatory System 1.06 0.985 – 1.14 0.121 792 8687 exclusion phecode
426.91 Cardiac pacemaker in situ Circulatory System 1.06 0.986 – 1.15 0.112 740 7958 exclusion phecode
427 Cardiac dysrhythmias Circulatory System 1.05 1.02 – 1.07 5.07e-05 8219 78159 exclusion phecode
427.1 Paroxysmal tachycardia, unspecified Circulatory System 1.04 0.977 – 1.11 0.219 1095 12052 exclusion phecode
427.11 Paroxysmal supraventricular tachycardia Circulatory System 1.04 0.973 – 1.12 0.23 832 8998 exclusion phecode
427.12 Paroxysmal ventricular tachycardia Circulatory System 1.02 0.909 – 1.15 0.7 284 3357 exclusion phecode
427.2 Atrial fibrillation and flutter Circulatory System 1.05 1.02 – 1.08 0.00131 4745 48108 exclusion phecode
427.3 Other specified cardiac dysrhythmias Circulatory System 1.07 1 – 1.13 0.0414 1129 11549 exclusion phecode
427.4 Cardiac arrest and ventricular fibrillation Circulatory System 1.01 0.905 – 1.14 0.811 318 4245 exclusion phecode
427.41 Ventricular fibrillation and flutter Circulatory System 0.839 0.686 – 1.03 0.0883 98 1221 exclusion phecode
427.42 Cardiac arrest Circulatory System 1.09 0.958 – 1.23 0.197 260 3530 exclusion phecode
427.5 Arrhythmia (cardiac) NOS Circulatory System 0.972 0.865 – 1.09 0.634 303 3609 exclusion phecode
427.6 Premature beats Circulatory System 1.2 1.03 – 1.39 0.0172 189 2035 exclusion phecode
427.61 Supraventricular premature beats Circulatory System 1.08 0.817 – 1.42 0.605 50 443 exclusion phecode
427.7 Tachycardia NOS Circulatory System 0.992 0.919 – 1.07 0.835 731 8596 exclusion phecode
427.8 Sinoatrial node dysfunction (Bradycardia) Circulatory System 1.11 0.942 – 1.3 0.219 163 1407 exclusion phecode
427.9 Palpitations Circulatory System 1.08 1.03 – 1.14 0.00387 1525 15377 exclusion phecode
428 Congestive heart failure; nonhypertensive Circulatory System 1.06 1 – 1.11 0.041 1543 20061 exclusion phecode
428.1 Congestive heart failure (CHF) NOS Circulatory System 1.05 0.959 – 1.14 0.301 539 7651 exclusion phecode
428.2 Heart failure NOS Circulatory System 1.04 0.983 – 1.1 0.167 1227 15827 exclusion phecode
429
Ill-defined descriptions and complications of
Ill-defined descriptions and complications of heart disease
 Circulatory System 1.04 0.911 – 1.18 0.587 253 2690 exclusion phecode
429.1 Heart transplant/surgery Circulatory System 0.726 0.442 – 1.19 0.206 13 231 exclusion phecode
429.2 Abnormal function study of cardiovascular system Circulatory System 1.09 0.936 – 1.27 0.272 181 1921 exclusion phecode
429.3 Symptoms involving cardiovascular system Circulatory System 0.93 0.73 – 1.19 0.559 72 783 exclusion phecode
430 Intracranial hemorrhage Circulatory System 1.14 1.05 – 1.24 0.00244 609 7151 exclusion phecode
430.1 Subarachnoid hemorrhage Circulatory System 1.11 0.971 – 1.26 0.129 244 3341 exclusion phecode
430.2 Intracerebral hemorrhage Circulatory System 1.22 1.08 – 1.39 0.00171 259 2838 exclusion phecode
430.3 Subdural hemorrhage Circulatory System 0.938 0.766 – 1.15 0.534 103 934 exclusion phecode
433 Cerebrovascular disease Circulatory System 1.07 1.03 – 1.11 0.001 2703 32008 exclusion phecode
433.1 Occlusion and stenosis of precerebral arteries Circulatory System 1.14 1 – 1.3 0.0468 256 4162 exclusion phecode
433.12 Cerebral atherosclerosis Circulatory System 1.16 0.916 – 1.48 0.215 78 813 exclusion phecode
433.2 Occlusion of cerebral arteries Circulatory System 1.05 0.991 – 1.11 0.0968 1303 15396 exclusion phecode
433.21
Cerebral artery occlusion, with cerebral
Cerebral artery occlusion, with cerebral infarction
 Circulatory System 1.08 0.982 – 1.18 0.115 512 6058 exclusion phecode
433.3 Cerebral ischemia Circulatory System 1.07 0.998 – 1.15 0.0578 888 10645 exclusion phecode
433.31 Transient cerebral ischemia Circulatory System 1.04 0.963 – 1.13 0.298 657 7775 exclusion phecode
433.5 Cerebral aneurysm Circulatory System 1.2 0.995 – 1.46 0.0567 108 1628 exclusion phecode
433.8 Late effects of cerebrovascular disease Circulatory System 1.11 1.01 – 1.23 0.0357 396 4796 exclusion phecode
440 Atherosclerosis Circulatory System 1.04 0.9 – 1.21 0.578 193 4936 exclusion phecode
440.1 Atherosclerosis of renal artery Circulatory System 1 0.645 – 1.56 0.987 20 434 exclusion phecode
440.2 Atherosclerosis of the extremities Circulatory System 1.15 0.918 – 1.45 0.219 79 2850 exclusion phecode
440.9 Atherosclerosis of aorta Circulatory System 1.09 0.812 – 1.46 0.567 46 1110 exclusion phecode
441 Vascular insufficiency of intestine Circulatory System 1.04 0.895 – 1.2 0.639 194 2433 exclusion phecode
441.1 Acute vascular insufficiency of intestine Circulatory System 0.938 0.762 – 1.15 0.543 95 1136 exclusion phecode
442 Other aneurysm Circulatory System 0.992 0.896 – 1.1 0.881 396 6566 exclusion phecode
442.1 Aortic aneurysm Circulatory System 0.975 0.861 – 1.1 0.686 256 5020 exclusion phecode
442.11 Abdominal aortic aneurysm Circulatory System 1.16 0.948 – 1.41 0.152 98 3144 exclusion phecode
442.2 Aneurysm of iliac artery Circulatory System 1.14 0.738 – 1.77 0.548 20 318 exclusion phecode
442.3 Aneurysm of artery of lower extremity Circulatory System 0.913 0.66 – 1.26 0.584 41 615 exclusion phecode
442.4 Arterial dissection Circulatory System 0.774 0.5 – 1.2 0.252 22 217 exclusion phecode
442.8 Aneurysm of other specified artery Circulatory System 0.988 0.77 – 1.27 0.922 69 736 exclusion phecode
443 Peripheral vascular disease Circulatory System 1.06 0.985 – 1.13 0.124 842 14759 exclusion phecode
443.1 Raynaud's syndrome Circulatory System 1.03 0.928 – 1.14 0.577 396 4663 exclusion phecode
443.7
Peripheral angiopathy in diseases classified
Peripheral angiopathy in diseases classified elsewhere
 Circulatory System 1.1 0.903 – 1.34 0.347 106 1424 exclusion phecode
443.8 Other specified peripheral vascular diseases Circulatory System 1.05 0.98 – 1.14 0.158 764 13866 exclusion phecode
443.9 Peripheral vascular disease, unspecified Circulatory System 1.08 0.973 – 1.2 0.148 379 9380 exclusion phecode
444 Arterial embolism and thrombosis Circulatory System 1.09 0.919 – 1.3 0.313 136 3394 exclusion phecode
444.1
Arterial embolism and thrombosis of lower
Arterial embolism and thrombosis of lower extremity artery
 Circulatory System 1.16 0.912 – 1.48 0.225 67 1958 exclusion phecode
446 Polyarteritis nodosa and allied conditions Circulatory System 0.986 0.876 – 1.11 0.815 315 3206 exclusion phecode
446.4 Wegener's granulomatosis Circulatory System 1.32 1.04 – 1.68 0.021 76 689 exclusion phecode
446.5 Giant cell arteritis Circulatory System 0.852 0.719 – 1.01 0.0643 150 1582 exclusion phecode
446.9 Arteritis NOS Circulatory System 0.968 0.768 – 1.22 0.779 91 873 exclusion phecode
447 Other disorders of arteries and arterioles Circulatory System 1.08 0.94 – 1.25 0.271 205 4897 exclusion phecode
447.1 Stricture of artery Circulatory System 0.994 0.79 – 1.25 0.956 75 3085 exclusion phecode
448 Disease of capillaries Circulatory System 1.41 1.03 – 1.93 0.0346 40 541 exclusion phecode
450 Noninfectious disorders of lymphatic channels Circulatory System 1.04 0.92 – 1.18 0.509 271 2786 exclusion phecode
451 Phlebitis and thrombophlebitis Circulatory System 1.05 0.997 – 1.11 0.067 1478 14774 exclusion phecode
451.2
Phlebitis and thrombophlebitis of lower
Phlebitis and thrombophlebitis of lower extremities
 Circulatory System 1.06 1 – 1.12 0.0353 1392 13741 exclusion phecode
452 Other venous embolism and thrombosis Circulatory System 1.1 0.947 – 1.27 0.214 193 2206 exclusion phecode
454 Varicose veins Circulatory System 1.07 1.03 – 1.1 7e-05 4319 44774 exclusion phecode
454.1 Varicose veins of lower extremity Circulatory System 1.07 1.04 – 1.1 3.05e-05 4467 46144 exclusion phecode
454.11 Varicose veins of lower extremity, symptomtic Circulatory System 1.05 0.905 – 1.21 0.537 204 2506 exclusion phecode
455 Hemorrhoids Circulatory System 1.04 1.02 – 1.06 0.000796 8636 91147 exclusion phecode
456 Chronic venous insufficiency [CVI] Circulatory System 1.07 0.825 – 1.37 0.628 61 634 exclusion phecode
457
Encounter for long-term (current) use of
Encounter for long-term (current) use of anticoagulants, antithrombotics, aspirin
 Circulatory System 0.743 0.537 – 1.03 0.0722 37 354 exclusion phecode
458 Hypotension Circulatory System 1.05 1 – 1.1 0.0402 2004 21625 exclusion phecode
458.1 Orthostatic hypotension Circulatory System 1 0.914 – 1.1 0.931 470 4828 exclusion phecode
458.2 Iatrogenic hypotension Circulatory System 1.05 0.831 – 1.32 0.697 77 887 exclusion phecode
458.9 Hypotension NOS Circulatory System 1.07 1.01 – 1.13 0.0305 1194 13205 exclusion phecode
459 Other disorders of circulatory system Circulatory System 1.06 1.03 – 1.09 0.000206 5313 60709 exclusion phecode
459.1 Hemorrhage NOS Circulatory System 1.06 0.797 – 1.4 0.702 52 519 exclusion phecode
459.9 Circulatory disease NEC Circulatory System 1.06 1.03 – 1.09 0.000108 5265 60137 exclusion phecode
464 Acute sinusitis Respiratory 1.23 0.959 – 1.58 0.103 66 782 exclusion phecode
465
Acute upper respiratory infections of multiple
Acute upper respiratory infections of multiple or unspecified sites
 Respiratory 1.08 1 – 1.16 0.0364 835 8951 exclusion phecode
465.2 Acute pharyngitis Respiratory 1.12 0.999 – 1.26 0.052 312 3235 exclusion phecode
465.4 Acute laryngitis and tracheitis Respiratory 0.978 0.742 – 1.29 0.874 60 621 exclusion phecode
470 Septal Deviations/Turbinate Hypertrophy Respiratory 1.04 0.993 – 1.1 0.0903 1669 18150 exclusion phecode
471 Nasal polyps Respiratory 1.07 1.01 – 1.14 0.0266 1179 12255 exclusion phecode
472 Chronic pharyngitis and nasopharyngitis Respiratory 1.09 0.982 – 1.21 0.105 393 3663 exclusion phecode
473 Diseases of the larynx and vocal cords Respiratory 1.06 0.983 – 1.14 0.128 718 9891 exclusion phecode
473.1 Chronic laryngitis Respiratory 1.2 0.845 – 1.7 0.311 33 410 exclusion phecode
473.3 Paralysis/spasm of vocal cords or larynx Respiratory 0.97 0.786 – 1.2 0.774 93 991 exclusion phecode
473.4 Voice disturbance Respiratory 1.05 0.934 – 1.18 0.414 305 4151 exclusion phecode
474 Acute and chronic tonsillitis Respiratory 1.1 1.01 – 1.19 0.0256 640 7194 exclusion phecode
474.1 Acute tonsillitis Respiratory 1.14 0.991 – 1.31 0.0663 211 2235 exclusion phecode
474.2 Chronic tonsillitis and adenoiditis Respiratory 1.12 1.02 – 1.24 0.0242 411 4577 exclusion phecode
475 Chronic sinusitis Respiratory 1.05 0.982 – 1.12 0.155 977 10071 exclusion phecode
476 Allergic rhinitis Respiratory 1.01 0.918 – 1.12 0.793 440 4181 exclusion phecode
477 Epistaxis or throat hemorrhage Respiratory 1.03 0.963 – 1.11 0.364 870 9128 exclusion phecode
478 Throat pain Respiratory 0.982 0.825 – 1.17 0.843 130 1520 exclusion phecode
479 Other upper respiratory disease Respiratory 1.07 1.01 – 1.13 0.0167 1468 15956 exclusion phecode
480 Pneumonia Respiratory 1.04 0.998 – 1.08 0.0668 2916 38931 exclusion phecode
480.1 Bacterial pneumonia Respiratory 1.01 0.964 – 1.06 0.648 1880 25119 exclusion phecode
480.11 Pneumococcal pneumonia Respiratory 1.01 0.958 – 1.06 0.769 1639 22276 exclusion phecode
480.12 Pseudomonal pneumonia Respiratory 0.854 0.575 – 1.27 0.433 24 342 exclusion phecode
480.2 Viral pneumonia Respiratory 0.669 0.46 – 0.973 0.0355 27 277 exclusion phecode
480.3 Pneumonia due to fungus (mycoses) Respiratory 0.834 0.571 – 1.22 0.35 26 380 exclusion phecode
480.5 Bronchopneumonia and lung abscess Respiratory 0.985 0.861 – 1.13 0.829 222 2965 exclusion phecode
481 Influenza Respiratory 1.15 0.949 – 1.4 0.155 114 1322 exclusion phecode
483 Acute bronchitis and bronchiolitis Respiratory 1.29 0.983 – 1.68 0.0663 56 754 exclusion phecode
495 Asthma Respiratory 1.09 1.07 – 1.12 3.18e-17 9620 101869 exclusion phecode
495.2 Asthma with exacerbation Respiratory 1.01 0.817 – 1.26 0.904 82 1039 exclusion phecode
496 Chronic airway obstruction Respiratory 1.11 1.06 – 1.17 1.99e-05 1627 39784 exclusion phecode
496.1 Emphysema Respiratory 1.06 0.897 – 1.26 0.474 129 6691 exclusion phecode
496.2 Chronic bronchitis Respiratory 1.11 0.981 – 1.26 0.0967 249 11507 exclusion phecode
496.21 Obstructive chronic bronchitis Respiratory 1.14 0.985 – 1.32 0.0795 183 10607 exclusion phecode
496.3 Bronchiectasis Respiratory 1.06 0.978 – 1.14 0.163 706 7503 exclusion phecode
497 Bronchitis Respiratory 1.08 0.935 – 1.26 0.283 188 2525 exclusion phecode
500 Lung disease due to external agents Respiratory 1.15 0.911 – 1.45 0.241 76 1435 exclusion phecode
500.1 Extrinsic allergic alveolitis Respiratory 1.13 0.798 – 1.61 0.484 33 298 exclusion phecode
500.2 Pneumoconiosis Respiratory 0.983 0.694 – 1.39 0.922 33 767 exclusion phecode
501 Pneumonitis due to inhalation of food or vomitus Respiratory 0.955 0.822 – 1.11 0.551 186 2427 exclusion phecode
502 Postinflammatory pulmonary fibrosis Respiratory 0.999 0.872 – 1.15 0.994 223 3446 exclusion phecode
503 Pulmonary congestion and hypostasis Respiratory 1.16 0.976 – 1.39 0.0903 131 1964 exclusion phecode
504 Other alveolar and parietoalveolar pneumonopathy Respiratory 1.15 0.931 – 1.43 0.192 91 1247 exclusion phecode
505 Other pulmonary inflamation or edema Respiratory 1.14 0.739 – 1.74 0.563 23 220 exclusion phecode
506 Empyema and pneumothorax Respiratory 0.893 0.789 – 1.01 0.0724 274 4212 exclusion phecode
507 Pleurisy; pleural effusion Respiratory 0.986 0.941 – 1.03 0.536 2001 23829 exclusion phecode
508
Pulmonary collapse; interstitial and
Pulmonary collapse; interstitial and compensatory emphysema
 Respiratory 1.1 1.01 – 1.19 0.0267 616 7601 exclusion phecode
509 Respiratory failure, insufficiency, arrest Respiratory 0.977 0.899 – 1.06 0.583 593 9659 exclusion phecode
509.1 Respiratory failure Respiratory 1 0.91 – 1.1 0.984 438 7624 exclusion phecode
509.2 Respiratory insufficiency Respiratory 0.992 0.896 – 1.1 0.882 388 6742 exclusion phecode
509.5 Respiratory arrest Respiratory 1.04 0.785 – 1.39 0.77 51 557 exclusion phecode
509.8
Dependence on respirator [Ventilator] or
Dependence on respirator [Ventilator] or supplemental oxygen
 Respiratory 0.973 0.793 – 1.19 0.791 97 1491 exclusion phecode
510 Other diseases of lung Respiratory 1.12 0.959 – 1.31 0.153 168 2879 exclusion phecode
512 Other symptoms of respiratory system Respiratory 1.05 1.01 – 1.09 0.0108 3109 34933 exclusion phecode
512.1 Wheezing Respiratory 1.07 0.859 – 1.34 0.537 81 839 exclusion phecode
512.2 Painful respiration Respiratory 1.16 0.9 – 1.49 0.255 63 860 exclusion phecode
512.7 Shortness of breath Respiratory 1.05 1.01 – 1.1 0.0283 1953 22539 exclusion phecode
512.8 Cough Respiratory 1.02 0.955 – 1.09 0.574 1018 11121 exclusion phecode
512.9 Other dyspnea Respiratory 1.11 0.994 – 1.24 0.0653 323 3506 exclusion phecode
513 Respiratory abnormalities Respiratory 1.03 0.889 – 1.19 0.717 201 2282 exclusion phecode
513.3 Hypoventilation Respiratory 1.07 0.738 – 1.54 0.729 26 310 exclusion phecode
513.4 Hyperventilation Respiratory 1.1 0.898 – 1.35 0.358 102 1105 exclusion phecode
513.8 Disorders of diaphragm Respiratory 0.955 0.705 – 1.29 0.768 47 511 exclusion phecode
514 Abnormal findings examination of lungs Respiratory 1.03 0.946 – 1.13 0.481 536 9167 exclusion phecode
516 Abnormal sputum Respiratory 1.07 0.977 – 1.17 0.149 511 8004 exclusion phecode
516.1 Hemoptysis Respiratory 1.07 0.976 – 1.17 0.15 503 7778 exclusion phecode
519
Other diseases of respiratory system, not
Other diseases of respiratory system, not elsewhere classified
 Respiratory 1.06 1.02 – 1.1 0.00399 2958 35949 exclusion phecode
519.2 Respiratory complications Respiratory 1.15 0.894 – 1.48 0.276 67 1239 exclusion phecode
519.8 Other diseases of respiratory system, NEC Respiratory 1.06 1.02 – 1.1 0.00239 2797 33997 exclusion phecode
519.9
Symptoms involving respiratory system and other
Symptoms involving respiratory system and other chest symptoms
 Respiratory 0.933 0.777 – 1.12 0.452 130 1240 exclusion phecode
520 Disorders of tooth development Digestive 0.975 0.908 – 1.05 0.483 836 8253 exclusion phecode
520.1 Hereditary disturbances in tooth structure Digestive 0.638 0.376 – 1.08 0.0952 15 218 exclusion phecode
520.2 Disturbances in tooth eruption Digestive 0.972 0.911 – 1.04 0.39 995 9619 exclusion phecode
521 Diseases of hard tissues of teeth Digestive 0.976 0.916 – 1.04 0.46 1079 12026 exclusion phecode
521.1 Dental caries Digestive 0.987 0.926 – 1.05 0.683 1071 12064 exclusion phecode
522 Diseases of pulp and periapical tissues Digestive 1.06 0.978 – 1.16 0.149 615 7109 exclusion phecode
522.5 Periapical abscess Digestive 1.05 0.945 – 1.16 0.381 414 4722 exclusion phecode
523 Gingival and periodontal diseases Digestive 1.1 1.01 – 1.19 0.0256 619 6831 exclusion phecode
523.1 Gingivitis Digestive 1.22 0.912 – 1.64 0.18 42 421 exclusion phecode
523.3 Periodontitis (acute or chronic) Digestive 1.05 0.948 – 1.16 0.365 436 4813 exclusion phecode
523.31 Acute periodontitis Digestive 1.04 0.912 – 1.19 0.544 243 2765 exclusion phecode
523.32 Chronic periodontitis Digestive 1 0.868 – 1.16 0.963 212 2262 exclusion phecode
524 Dentofacial anomalies, including malocclusion Digestive 0.957 0.806 – 1.14 0.616 137 1333 exclusion phecode
524.3 Anomalies of tooth position/malocclusion Digestive 0.993 0.832 – 1.18 0.937 130 1206 exclusion phecode
525
Other diseases of the teeth and supporting
Other diseases of the teeth and supporting structures
 Digestive 1.02 0.953 – 1.09 0.585 981 10567 exclusion phecode
525.2 Atrophy of edentulous alveolar ridge Digestive 1.39 0.921 – 2.1 0.117 27 263 exclusion phecode
526 Diseases of the jaws Digestive 1.03 0.921 – 1.15 0.613 325 3737 exclusion phecode
526.1 Cysts of the jaws Digestive 1.05 0.86 – 1.28 0.627 102 1245 exclusion phecode
526.3 Anomalies of jaw size/symmetry Digestive 1.37 0.951 – 1.97 0.0913 26 243 exclusion phecode
526.4 Temporomandibular joint disorders Digestive 1.17 0.955 – 1.43 0.131 97 1012 exclusion phecode
526.41 Temporomandibular joint disorder, unspecified Digestive 1.17 0.951 – 1.43 0.139 94 994 exclusion phecode
526.5 Inflammatory conditions of jaw Digestive 0.926 0.657 – 1.31 0.662 31 429 exclusion phecode
526.9 Jaw disease NOS Digestive 0.852 0.686 – 1.06 0.148 84 976 exclusion phecode
527 Diseases of the salivary glands Digestive 1.09 0.946 – 1.25 0.243 226 2813 exclusion phecode
527.1 Hypertrophy of salivary gland Digestive 0.994 0.696 – 1.42 0.974 32 352 exclusion phecode
527.2 Sialoadenitis Digestive 1.07 0.872 – 1.31 0.526 108 1472 exclusion phecode
527.7 Disturbance of salivary secretion Digestive 1.29 0.834 – 2 0.252 21 234 exclusion phecode
527.8 Other specified diseases of the salivary glands Digestive 1.15 0.824 – 1.61 0.409 36 467 exclusion phecode
528
Diseases of the oral soft tissues, excluding
Diseases of the oral soft tissues, excluding lesions specific for gingiva and tongue
 Digestive 1.03 0.978 – 1.09 0.241 1334 15394 exclusion phecode
528.1 Stomatitis and mucositis Digestive 0.983 0.846 – 1.14 0.817 191 1809 exclusion phecode
528.11 Stomatitis and mucositis (ulcerative) Digestive 1.01 0.853 – 1.19 0.946 159 1493 exclusion phecode
528.12 Oral aphthae Digestive 0.839 0.589 – 1.2 0.332 33 345 exclusion phecode
528.3 Cellulitis and abscess of oral soft tissues Digestive 0.905 0.69 – 1.19 0.471 50 743 exclusion phecode
528.4 Cysts of oral soft tissues Digestive 0.949 0.682 – 1.32 0.754 42 509 exclusion phecode
528.41 Cyst of the salivary gland Digestive 0.887 0.614 – 1.28 0.524 35 387 exclusion phecode
528.5 Diseases of lips Digestive 0.971 0.852 – 1.11 0.664 248 2706 exclusion phecode
528.6 Leukoplakia of oral mucosa Digestive 1.07 0.862 – 1.32 0.554 91 1196 exclusion phecode
528.7 Sialolithiasis Digestive 0.982 0.799 – 1.21 0.863 95 1263 exclusion phecode
529 Diseases and other conditions of the tongue Digestive 1.02 0.92 – 1.12 0.76 424 4926 exclusion phecode
529.1 Glossitis Digestive 0.935 0.76 – 1.15 0.53 100 1169 exclusion phecode
530 Diseases of esophagus Digestive 1.09 1.07 – 1.11 4.67e-19 11804 109669 exclusion phecode
530.1 Esophagitis, GERD and related diseases Digestive 1.1 1.07 – 1.12 1.26e-19 11040 106772 exclusion phecode
530.11 GERD Digestive 1.1 1.07 – 1.12 2.17e-15 8116 88546 exclusion phecode
530.12 Ulcer of esophagus Digestive 1.07 1.02 – 1.12 0.00719 1750 19410 exclusion phecode
530.14 Reflux esophagitis Digestive 1.12 1.08 – 1.16 8.62e-11 3646 40537 exclusion phecode
530.2 Esophageal bleeding (varices/hemorrhage) Digestive 1.02 0.941 – 1.12 0.57 577 6519 exclusion phecode
530.3 Stricture and stenosis of esophagus Digestive 0.969 0.891 – 1.05 0.451 635 6920 exclusion phecode
530.5 Disorders of esophageal motility Digestive 1.06 0.934 – 1.21 0.36 245 2551 exclusion phecode
530.6 Diverticulum of esophagus, acquired Digestive 0.869 0.648 – 1.16 0.347 52 536 exclusion phecode
530.7 Gastroesophageal laceration-hemorrhage syndrome Digestive 1.13 0.933 – 1.36 0.213 113 1331 exclusion phecode
530.9 Heartburn Digestive 1.11 1.03 – 1.19 0.00671 792 8337 exclusion phecode
531 Peptic ulcer (excl. esophageal) Digestive 1.09 1.04 – 1.14 0.000119 2218 26758 exclusion phecode
531.1 Hemorrhage from gastrointestinal ulcer Digestive 1.11 0.952 – 1.28 0.188 188 2327 exclusion phecode
531.2 Gastric ulcer Digestive 1.1 1.04 – 1.16 0.000891 1324 15663 exclusion phecode
531.3 Duodenal ulcer Digestive 1.05 0.985 – 1.13 0.13 898 11132 exclusion phecode
531.4 Peptic ulcer, site unspecified Digestive 1.26 1.04 – 1.52 0.0195 117 1600 exclusion phecode
532 Dysphagia Digestive 1.1 1.05 – 1.15 9.71e-06 2382 25224 exclusion phecode
535 Gastritis and duodenitis Digestive 1.07 1.05 – 1.09 3.51e-10 9604 102418 exclusion phecode
535.1 Acute gastritis Digestive 1.02 0.921 – 1.13 0.718 404 4703 exclusion phecode
535.2 Atrophic gastritis Digestive 1.11 0.93 – 1.33 0.242 137 1378 exclusion phecode
535.6 Duodenitis Digestive 1.05 1.01 – 1.1 0.0167 2240 28909 exclusion phecode
535.8 Other specified gastritis Digestive 1.09 1.05 – 1.14 3.07e-06 2891 31775 exclusion phecode
535.9 Gastritis and duodenitis, NOS Digestive 1.19 0.844 – 1.68 0.318 37 447 exclusion phecode
536.8
Dyspepsia and other specified disorders of
Dyspepsia and other specified disorders of function of stomach
 Digestive 1.11 0.9 – 1.37 0.328 89 1020 exclusion phecode
537 Other disorders of stomach and duodenum Digestive 1.1 1.03 – 1.16 0.00282 1166 13242 exclusion phecode
540 Appendiceal conditions Digestive 1 0.943 – 1.06 0.957 1176 12316 exclusion phecode
540.1 Appendicitis Digestive 1.02 0.961 – 1.09 0.47 1097 11561 exclusion phecode
540.11 Acute appendicitis Digestive 0.985 0.923 – 1.05 0.643 995 10302 exclusion phecode
550 Abdominal hernia Digestive 1.07 1.05 – 1.09 5.6e-16 16103 111235 exclusion phecode
550.1 Inguinal hernia Digestive 1.02 0.996 – 1.06 0.0941 5284 42552 exclusion phecode
550.2 Diaphragmatic hernia Digestive 1.09 1.06 – 1.11 1.05e-14 9759 93168 exclusion phecode
550.3 Femoral hernia Digestive 1.01 0.882 – 1.15 0.899 221 2669 exclusion phecode
550.4 Umbilical hernia Digestive 1.09 1.03 – 1.16 0.00392 1206 13558 exclusion phecode
550.5 Ventral hernia Digestive 1.15 1.08 – 1.22 9.28e-06 1132 13325 exclusion phecode
555
Inflammatory bowel disease and other
Inflammatory bowel disease and other gastroenteritis and colitis
 Digestive 1.01 0.961 – 1.07 0.602 1457 17554 exclusion phecode
555.1 Regional enteritis Digestive 0.958 0.88 – 1.04 0.325 569 6990 exclusion phecode
555.2 Ulcerative colitis Digestive 1.03 0.965 – 1.1 0.396 1050 12422 exclusion phecode
555.21 Ulcerative colitis (chronic) Digestive 1.01 0.869 – 1.18 0.871 167 2185 exclusion phecode
556 Ulceration of the lower GI tract Digestive 1.13 1.02 – 1.26 0.025 357 4186 exclusion phecode
556.1 Ulceration of intestine Digestive 1.26 1.09 – 1.46 0.00139 218 2624 exclusion phecode
557 Intestinal malabsorption (non-celiac) Digestive 0.939 0.776 – 1.14 0.516 118 1162 exclusion phecode
557.1 Celiac disease Digestive 0.889 0.826 – 0.957 0.00182 794 7497 exclusion phecode
558 Noninfectious gastroenteritis Digestive 1.06 1.03 – 1.09 3.84e-05 5718 62667 exclusion phecode
559 Ileostomy status Digestive 1.04 0.952 – 1.14 0.387 549 6265 exclusion phecode
560 Intestinal obstruction without mention of hernia Digestive 0.98 0.928 – 1.04 0.48 1392 15542 exclusion phecode
560.1 Paralytic ileus Digestive 0.973 0.831 – 1.14 0.729 167 2027 exclusion phecode
560.2 Impaction of intestine Digestive 1.22 0.998 – 1.49 0.0522 104 1071 exclusion phecode
560.3 Peritoneal or intestinal adhesions Digestive 0.995 0.879 – 1.13 0.936 284 3305 exclusion phecode
560.4 Other intestinal obstruction Digestive 0.965 0.909 – 1.02 0.241 1196 13343 exclusion phecode
561 Symptoms involving digestive system Digestive 1.09 1.06 – 1.12 7.41e-10 6148 64179 exclusion phecode
561.1 Diarrhea Digestive 1.08 0.928 – 1.25 0.329 176 1880 exclusion phecode
561.2 Flatulence Digestive 1.04 0.957 – 1.12 0.378 669 6826 exclusion phecode
562 Diverticulosis and diverticulitis Digestive 1.05 1.03 – 1.07 1.53e-05 9034 82424 exclusion phecode
562.1 Diverticulosis Digestive 1.05 1.03 – 1.07 1.69e-05 9023 82402 exclusion phecode
563 Constipation Digestive 1.09 1.05 – 1.13 7.8e-07 3726 41364 exclusion phecode
564 Functional digestive disorders Digestive 1.09 1.06 – 1.11 9.3e-12 7615 82801 exclusion phecode
564.1 Irritable Bowel Syndrome Digestive 1.11 1.06 – 1.16 7.41e-06 2209 23067 exclusion phecode
564.8
Abnormal findings on exam of gastrointestinal
Abnormal findings on exam of gastrointestinal tract/ abdominal area
 Digestive 1.06 0.976 – 1.15 0.168 604 6584 exclusion phecode
564.9 Personal history of diseases of digestive system Digestive 1.09 1.05 – 1.12 3.02e-08 5038 58491 exclusion phecode
565 Anal and rectal conditions Digestive 1.03 1 – 1.07 0.0278 4653 56709 exclusion phecode
565.1 Anal and rectal polyp Digestive 1.01 0.968 – 1.06 0.594 2060 27593 exclusion phecode
567 Peritonitis and retroperitoneal infections Digestive 1.01 0.891 – 1.13 0.933 290 3516 exclusion phecode
568 Other disorders of peritoneum Digestive 1.08 1.02 – 1.15 0.00871 1191 13219 exclusion phecode
568.1
Peritoneal adhesions (postoperative)
Peritoneal adhesions (postoperative) (postinfection)
 Digestive 1.08 1.01 – 1.14 0.0179 1134 12548 exclusion phecode
569 Other disorders of intestine Digestive 1 0.947 – 1.06 0.992 1437 16346 exclusion phecode
569.1 Toxic gastroenteritis and colitis Digestive 1.09 0.84 – 1.41 0.521 64 560 exclusion phecode
569.2 Gastrointestinal complications Digestive 0.95 0.807 – 1.12 0.541 156 1893 exclusion phecode
571 Chronic liver disease and cirrhosis Digestive 1.1 1.03 – 1.17 0.00681 949 11451 exclusion phecode
571.5 Other chronic nonalcoholic liver disease Digestive 1.14 1.05 – 1.24 0.00164 580 6626 exclusion phecode
571.51 Cirrhosis of liver without mention of alcohol Digestive 1.12 0.808 – 1.55 0.497 38 392 exclusion phecode
571.6 Primary biliary cirrhosis Digestive 1.09 0.864 – 1.37 0.474 82 1072 exclusion phecode
571.8
Liver abscess and sequelae of chronic liver
Liver abscess and sequelae of chronic liver disease
 Digestive 1.03 0.912 – 1.16 0.65 288 3604 exclusion phecode
571.81 Portal hypertension Digestive 0.992 0.849 – 1.16 0.922 168 1993 exclusion phecode
572 Ascites (non malignant) Digestive 0.935 0.855 – 1.02 0.141 547 5834 exclusion phecode
573 Other disorders of liver Digestive 1.04 0.948 – 1.14 0.427 521 5754 exclusion phecode
573.2 Liver replaced by transplant Digestive 1.06 0.781 – 1.44 0.703 40 362 exclusion phecode
573.3 Hepatomegaly Digestive 1.26 0.997 – 1.59 0.0533 80 1104 exclusion phecode
573.5 Jaundice (not of newborn) Digestive 1.08 0.962 – 1.21 0.194 332 3310 exclusion phecode
573.7 Abnormal results of function study of liver Digestive 1.05 0.986 – 1.11 0.136 1248 13475 exclusion phecode
573.9 Abnormal serum enzyme levels Digestive 1.22 0.931 – 1.6 0.148 56 822 exclusion phecode
574 Cholelithiasis and cholecystitis Digestive 1.1 1.07 – 1.13 3.63e-13 6192 63120 exclusion phecode
574.1 Cholelithiasis Digestive 1.1 1.07 – 1.13 3.39e-11 5428 54888 exclusion phecode
574.11 Cholelithiasis with acute cholecystitis Digestive 1.12 1.03 – 1.22 0.0116 574 5936 exclusion phecode
574.12 Cholelithiasis with other cholecystitis Digestive 1.09 1.05 – 1.14 8.44e-05 2201 22145 exclusion phecode
574.2 Calculus of bile duct Digestive 1.08 1.01 – 1.15 0.0316 972 10568 exclusion phecode
574.3 Cholecystitis without cholelithiasis Digestive 1.07 1.01 – 1.15 0.0325 1002 10999 exclusion phecode
575 Other biliary tract disease Digestive 1.08 1.02 – 1.14 0.0077 1479 15316 exclusion phecode
575.1 Cholangitis Digestive 1.06 0.906 – 1.23 0.479 183 1802 exclusion phecode
575.2 Obstruction of bile duct Digestive 1.12 0.99 – 1.27 0.073 277 2903 exclusion phecode
575.6 Cholesterolosis of gallbladder Digestive 1.12 0.962 – 1.29 0.147 205 1869 exclusion phecode
575.7 Other disorders of gallbladder Digestive 1.03 0.947 – 1.13 0.456 554 5685 exclusion phecode
575.8 Other disorders of biliary tract Digestive 1.13 1.02 – 1.26 0.0213 373 4188 exclusion phecode
575.9
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of biliary tract
 Digestive 1.18 0.978 – 1.43 0.0828 116 1434 exclusion phecode
577 Diseases of pancreas Digestive 1.04 0.971 – 1.11 0.268 944 10234 exclusion phecode
577.1 Acute pancreatitis Digestive 1.07 0.988 – 1.15 0.0964 732 7711 exclusion phecode
577.2 Chronic pancreatitis Digestive 1.02 0.849 – 1.22 0.849 136 1885 exclusion phecode
577.3 Cyst and pseudocyst of pancreas Digestive 0.99 0.81 – 1.21 0.919 106 1390 exclusion phecode
578 Gastrointestinal hemorrhage Digestive 1.05 1.03 – 1.08 1.4e-05 7495 80360 exclusion phecode
578.1 Hematemesis Digestive 1.15 1.06 – 1.26 0.000972 577 7486 exclusion phecode
578.2 Blood in stool Digestive 1.06 0.985 – 1.13 0.124 857 9960 exclusion phecode
578.8 Hemorrhage of rectum and anus Digestive 1.05 1.02 – 1.08 0.00228 4919 51643 exclusion phecode
578.9 Hemorrhage of gastrointestinal tract Digestive 1.08 1.03 – 1.13 0.002 1900 20334 exclusion phecode
579 Other symptoms involving abdomen and pelvis Digestive 0.979 0.898 – 1.07 0.633 575 6199 exclusion phecode
579.2 Splenomegaly Digestive 1.04 0.88 – 1.23 0.633 147 1592 exclusion phecode
579.8 Nonspecific abnormal findings in stool contents Digestive 1.02 0.934 – 1.1 0.713 613 6451 exclusion phecode
580 Nephritis; nephrosis; renal sclerosis Genitourinary 1.04 0.953 – 1.14 0.351 502 5744 exclusion phecode
580.1 Glomerulonephritis Genitourinary 1.11 0.999 – 1.24 0.0523 348 3934 exclusion phecode
580.11 Proliferative glomerulonephritis Genitourinary 1.3 0.885 – 1.9 0.183 28 245 exclusion phecode
580.12 Non-proliferative glomerulonephritis Genitourinary 0.932 0.697 – 1.24 0.631 52 549 exclusion phecode
580.14 Chronic glomerulonephritis, NOS Genitourinary 1.1 0.974 – 1.24 0.125 281 3254 exclusion phecode
580.2
Nephrotic syndrome without mention of
Nephrotic syndrome without mention of glomerulonephritis
 Genitourinary 1.08 0.918 – 1.27 0.352 155 1728 exclusion phecode
580.3
Nephritis and nephropathy without mention of
Nephritis and nephropathy without mention of glomerulonephritis
 Genitourinary 1.01 0.8 – 1.28 0.933 70 925 exclusion phecode
580.32
Nephritis and nephropathy with pathological
Nephritis and nephropathy with pathological lesion
 Genitourinary 0.976 0.779 – 1.22 0.834 75 941 exclusion phecode
585 Renal failure Genitourinary 1.05 1 – 1.09 0.0388 2195 25450 exclusion phecode
585.1 Acute renal failure Genitourinary 1.01 0.958 – 1.07 0.655 1369 16434 exclusion phecode
585.2 Renal failure NOS Genitourinary 1.08 0.985 – 1.19 0.101 483 5310 exclusion phecode
585.3 Chronic renal failure [CKD] Genitourinary 1.11 1.03 – 1.19 0.00356 868 9686 exclusion phecode
585.31 Renal dialysis Genitourinary 1.1 0.944 – 1.28 0.225 180 1861 exclusion phecode
586 Other disorders of the kidney and ureters Genitourinary 1.05 0.99 – 1.12 0.0994 1120 12492 exclusion phecode
586.1 Anatomical abnormatilies of kidney and ureters Genitourinary 1.08 0.856 – 1.37 0.51 69 789 exclusion phecode
586.11 Small kidney Genitourinary 1.04 0.811 – 1.34 0.739 61 693 exclusion phecode
586.2 Cyst of kidney, acquired Genitourinary 1.04 0.938 – 1.15 0.464 406 4567 exclusion phecode
586.3 Vascular disorders of kidney/hypertrophy Genitourinary 1.07 0.707 – 1.61 0.755 19 304 exclusion phecode
586.4 Stricture/obstruction of ureter Genitourinary 1.09 0.972 – 1.22 0.142 324 3461 exclusion phecode
587 Kidney replaced by transpant Genitourinary 1.04 0.872 – 1.24 0.655 132 1367 exclusion phecode
588 Disorders resulting from impaired renal function Genitourinary 0.808 0.58 – 1.13 0.206 36 411 exclusion phecode
589 Abnormal results of function study of kidney Genitourinary 1.07 0.767 – 1.49 0.694 35 446 exclusion phecode
590 Pyelonephritis Genitourinary 1.11 1.01 – 1.22 0.0268 466 5488 exclusion phecode
591 Urinary tract infection Genitourinary 1.09 1.06 – 1.13 1.4e-08 4557 48269 exclusion phecode
592 Cystitis and urethritis Genitourinary 1.04 0.977 – 1.11 0.217 1082 11731 exclusion phecode
592.1 Cystitis Genitourinary 1.03 0.971 – 1.1 0.298 1067 11511 exclusion phecode
592.11 Acute cystitis Genitourinary 1.08 0.788 – 1.47 0.645 43 512 exclusion phecode
592.12 Chronic cystitis Genitourinary 1.08 0.959 – 1.21 0.209 305 3432 exclusion phecode
592.13 Chronic interstitial cystitis Genitourinary 0.912 0.746 – 1.12 0.373 112 1011 exclusion phecode
592.2 Urethritis and urethral syndrome Genitourinary 0.968 0.745 – 1.26 0.809 57 623 exclusion phecode
593 Hematuria Genitourinary 1.03 1.01 – 1.06 0.016 5708 59932 exclusion phecode
594 Urinary calculus Genitourinary 1.07 1.02 – 1.12 0.00212 2295 23140 exclusion phecode
594.1 Calculus of kidney Genitourinary 1.07 1.01 – 1.14 0.0277 1121 11622 exclusion phecode
594.2 Calculus of lower urinary tract Genitourinary 0.972 0.853 – 1.11 0.673 254 2538 exclusion phecode
594.3 Calculus of ureter Genitourinary 1.13 1.06 – 1.21 0.000465 877 8747 exclusion phecode
594.8 Renal colic Genitourinary 1.07 0.995 – 1.16 0.0686 768 7438 exclusion phecode
595 Hydronephrosis Genitourinary 1.06 0.98 – 1.14 0.146 723 7056 exclusion phecode
596 Other disorders of bladder Genitourinary 1.02 0.979 – 1.05 0.408 3309 34896 exclusion phecode
596.1 Bladder neck obstruction Genitourinary 0.984 0.908 – 1.07 0.702 666 6298 exclusion phecode
596.5 Functional disorders of bladder Genitourinary 1.11 1.02 – 1.21 0.021 567 6365 exclusion phecode
597 Other disorders of urethra and urinary tract Genitourinary 1.07 1.02 – 1.13 0.0101 1480 14618 exclusion phecode
597.1 Urethral stricture (not specified as infectious) Genitourinary 1.09 1.03 – 1.15 0.00462 1256 12184 exclusion phecode
597.2 Urinary complications NEC Genitourinary 1.26 0.859 – 1.84 0.239 28 304 exclusion phecode
598 Abnormal findings on examination of urine Genitourinary 1.03 0.975 – 1.1 0.264 1202 12799 exclusion phecode
598.9
Other nonspecific findings on examination of
Other nonspecific findings on examination of urine
 Genitourinary 1 0.818 – 1.23 0.963 103 1119 exclusion phecode
599 Other symptoms/disorders or the urinary system Genitourinary 1.07 1.04 – 1.1 7.48e-08 6843 71868 exclusion phecode
599.1 Urinary obstruction Genitourinary 1.02 0.784 – 1.33 0.878 60 576 exclusion phecode
599.2 Retention of urine Genitourinary 1.01 0.967 – 1.06 0.648 2226 22837 exclusion phecode
599.3 Dysuria Genitourinary 0.996 0.902 – 1.1 0.932 417 4622 exclusion phecode
599.4 Urinary incontinence Genitourinary 1.08 1.04 – 1.12 1.44e-05 3480 36870 exclusion phecode
599.5 Frequency of urination and polyuria Genitourinary 1.05 0.993 – 1.1 0.0907 1484 15081 exclusion phecode
599.6 Oliguria and anuria Genitourinary 1.15 0.797 – 1.66 0.455 31 369 exclusion phecode
599.8 Other symptoms involving urinary system Genitourinary 1.46 0.992 – 2.14 0.0548 29 238 exclusion phecode
599.9 Other abnormality of urination Genitourinary 1.12 1.03 – 1.21 0.00672 667 6813 exclusion phecode
600 Hyperplasia of prostate Genitourinary 1.02 0.989 – 1.06 0.178 3475 27554 exclusion phecode
601 Inflammatory diseases of prostate Genitourinary 1 0.926 – 1.08 0.993 709 6729 exclusion phecode
601.1 Prostatitis Genitourinary 1 0.916 – 1.09 0.999 551 4940 exclusion phecode
601.11 Acute prostatitis Genitourinary 0.917 0.739 – 1.14 0.434 91 760 exclusion phecode
601.12 Chronic prostatitis Genitourinary 1.03 0.917 – 1.16 0.626 312 2846 exclusion phecode
601.3 Orchitis and epididymitis Genitourinary 1.37 0.852 – 2.21 0.193 17 217 exclusion phecode
601.4 Balanoposthitis Genitourinary 1.08 0.874 – 1.32 0.49 92 956 exclusion phecode
601.8
Other inflammatory disorders of male genital
Other inflammatory disorders of male genital organs
 Genitourinary 0.956 0.767 – 1.19 0.685 88 1018 exclusion phecode
602 Other disorders of prostate Genitourinary 1.07 0.965 – 1.18 0.206 435 4154 exclusion phecode
603 Other disorders of testis Genitourinary 0.977 0.903 – 1.06 0.56 683 7271 exclusion phecode
603.1 Hydrocele Genitourinary 0.96 0.87 – 1.06 0.425 424 4371 exclusion phecode
604 Disorders of penis Genitourinary 1.07 1 – 1.14 0.0357 1108 11237 exclusion phecode
604.1 Redundant prepuce and phimosis/BXO Genitourinary 1.09 1.02 – 1.16 0.0143 939 9318 exclusion phecode
605 Erectile dysfunction [ED] Genitourinary 0.954 0.745 – 1.22 0.708 68 900 exclusion phecode
608 Other disorders of male genital organs Genitourinary 1.04 0.974 – 1.11 0.24 961 9451 exclusion phecode
609 Male infertility and abnormal spermatozoa Genitourinary 1.43 1.14 – 1.78 0.00169 79 684 exclusion phecode
609.1 Infertility, male Genitourinary 1.39 0.955 – 2.02 0.0855 32 261 exclusion phecode
609.2 Abnormal spermatozoa Genitourinary 1.41 1.08 – 1.84 0.0115 55 508 exclusion phecode
610 Benign mammary dysplasias Genitourinary 1.08 1.01 – 1.15 0.0161 1059 10940 exclusion phecode
610.1 Cystic mastopathy Genitourinary 1.04 0.934 – 1.15 0.491 391 4089 exclusion phecode
610.2 Fibroadenosis of breast Genitourinary 1.14 0.962 – 1.36 0.127 134 1331 exclusion phecode
610.3 Fibrosclerosis of breast Genitourinary 1.1 0.907 – 1.33 0.339 112 1337 exclusion phecode
610.4 Benign neoplasm of breast Genitourinary 1.05 0.97 – 1.15 0.212 607 6147 exclusion phecode
610.8 Other specified benign mammary dysplasias Genitourinary 1.03 0.913 – 1.16 0.633 290 3060 exclusion phecode
611 Abnormal findings on mammogram or breast exam Genitourinary 0.945 0.871 – 1.03 0.174 649 6744 exclusion phecode
611.1 Abnormal mammogram Genitourinary 0.859 0.555 – 1.33 0.496 22 231 exclusion phecode
611.3 Lump or mass in breast Genitourinary 0.946 0.871 – 1.03 0.183 630 6564 exclusion phecode
612
Breast conditions, congenital or relating to
Breast conditions, congenital or relating to hormones
 Genitourinary 1.18 1.06 – 1.31 0.00321 362 3760 exclusion phecode
612.2 Hypertrophy of breast (Gynecomastia) Genitourinary 1.17 1.05 – 1.31 0.00515 342 3555 exclusion phecode
612.3 Congenital anomalies of breast Genitourinary – 31 320 exclusion phecode
613 Other nonmalignant breast conditions Genitourinary 1.05 0.972 – 1.14 0.208 647 7231 exclusion phecode
613.1 Inflammatory disease of breast Genitourinary 1.04 0.915 – 1.17 0.577 265 3132 exclusion phecode
613.5 Mastodynia Genitourinary 1.27 0.873 – 1.85 0.21 30 332 exclusion phecode
613.7 Other signs and symptoms in breast Genitourinary – 296 3055 exclusion phecode
613.8 Other specified disorders of breast Genitourinary – 124 1440 exclusion phecode
613.9 Breast disorder NOS Genitourinary – 92 925 exclusion phecode
614 Inflammatory diseases of female pelvic organs Genitourinary 1.06 1.02 – 1.11 0.00368 2369 25426 exclusion phecode
614.1
Pelvic peritoneal adhesions, female
Pelvic peritoneal adhesions, female (postoperative) (postinfection)
 Genitourinary 1.08 1.01 – 1.15 0.0198 1081 11390 exclusion phecode
614.3 Pelvic inflammatory disease (PID) Genitourinary 1.08 0.967 – 1.21 0.166 321 3786 exclusion phecode
614.31 Acute inflammatory pelvic disease Genitourinary 1.14 0.741 – 1.76 0.55 22 262 exclusion phecode
614.32 Chronic inflammatory pelvic disease Genitourinary 1.05 0.889 – 1.25 0.548 145 1891 exclusion phecode
614.33 Pelvic inflammatory disease, NOS Genitourinary 1.01 0.846 – 1.2 0.931 141 1600 exclusion phecode
614.4 Inflammatory diseases of uterus, except cervix Genitourinary 0.908 0.755 – 1.09 0.305 131 1230 exclusion phecode
614.5
Inflammatory disease of cervix, vagina, and
Inflammatory disease of cervix, vagina, and vulva
 Genitourinary 1.07 1 – 1.14 0.042 1046 11387 exclusion phecode
614.51 Cervicitis and endocervicitis Genitourinary 1.03 0.942 – 1.12 0.542 568 5826 exclusion phecode
614.52 Vaginitis and vulvovaginitis Genitourinary 1.09 0.933 – 1.26 0.285 181 1857 exclusion phecode
614.53 Cyst or abscess of Bartholin's gland Genitourinary 1.15 1.03 – 1.29 0.0153 314 3348 exclusion phecode
614.54 Abscess or ulceration of vulva Genitourinary 1.01 0.794 – 1.27 0.962 73 1206 exclusion phecode
615 Endometriosis Genitourinary 1.11 1.06 – 1.17 1.13e-05 1843 18054 exclusion phecode
617
Disorders secondary to childbirth, surgery
Disorders secondary to childbirth, surgery, trauma
 Genitourinary 0.911 0.752 – 1.1 0.344 115 1364 exclusion phecode
618 Genital prolapse Genitourinary 1.05 1.02 – 1.08 0.00145 5160 50543 exclusion phecode
618.1 Prolapse of vaginal walls Genitourinary 1.07 1.03 – 1.11 0.000164 3197 31982 exclusion phecode
618.2 Uterine/Uterovaginal prolapse Genitourinary 1.02 0.979 – 1.06 0.34 2439 23450 exclusion phecode
618.5 Prolapse of vaginal vault after hysterectomy Genitourinary 1.09 0.957 – 1.25 0.189 233 2250 exclusion phecode
618.6 Vaginal enterocele, congenital or acquired Genitourinary 1.07 0.95 – 1.21 0.259 297 2981 exclusion phecode
619 Noninflammatory female genital disorders Genitourinary 1.02 0.984 – 1.05 0.308 3784 38487 exclusion phecode
619.1
Noninflammatory disorders of ovary, fallopian
Noninflammatory disorders of ovary, fallopian tube, and broad ligament
 Genitourinary 1.02 0.911 – 1.15 0.706 324 3180 exclusion phecode
619.2 Disorders of uterus, NEC Genitourinary 0.986 0.935 – 1.04 0.612 1482 14593 exclusion phecode
619.3 Noninflammatory disorders of cervix Genitourinary 1.05 0.991 – 1.11 0.101 1289 12593 exclusion phecode
619.4 Noninflammatory disorders of vagina Genitourinary 0.997 0.924 – 1.08 0.947 748 7865 exclusion phecode
619.5 Noninflammatory disorders of vulva and perineum Genitourinary 1.04 0.955 – 1.14 0.34 535 5927 exclusion phecode
620 Dysplasia of female genital organs Genitourinary 1.14 0.752 – 1.74 0.531 27 299 exclusion phecode
621 Endometrial hyperplasia Genitourinary 1.04 0.95 – 1.14 0.391 501 4957 exclusion phecode
622 Polyp of female genital organs Genitourinary 1.01 0.985 – 1.05 0.336 4790 45430 exclusion phecode
622.1 Polyp of corpus uteri Genitourinary 1.02 0.981 – 1.05 0.386 3532 34125 exclusion phecode
622.2 Mucous polyp of cervix Genitourinary 1.01 0.955 – 1.06 0.844 1675 14857 exclusion phecode
623 Hypertrophy of female genital organs Genitourinary 1.04 0.956 – 1.13 0.354 605 5679 exclusion phecode
624 Symptoms involving female genital tract Genitourinary 1.12 1 – 1.24 0.0431 363 3438 exclusion phecode
624.1 Dystrophy of female genital tract Genitourinary 0.998 0.826 – 1.21 0.986 109 1014 exclusion phecode
624.2 Atrophy of female genital tract Genitourinary 1.13 0.974 – 1.31 0.108 191 1845 exclusion phecode
624.9 stress incontinence, female Genitourinary 1.1 1.05 – 1.14 1.53e-05 2425 25429 exclusion phecode
625
Pain and other symptoms associated with female
Pain and other symptoms associated with female genital organs
 Genitourinary 1.03 0.976 – 1.1 0.254 1238 12843 exclusion phecode
625.1 Dyspareunia Genitourinary 0.993 0.907 – 1.09 0.881 515 5319 exclusion phecode
626
Disorders of menstruation and other abnormal
Disorders of menstruation and other abnormal bleeding from female genital tract
 Genitourinary 1.06 1.04 – 1.09 2.73e-06 7178 50722 exclusion phecode
626.1 Irregular menstrual cycle/bleeding Genitourinary 1.07 1.04 – 1.1 9.7e-07 6269 48584 exclusion phecode
626.11 Absent or infrequent menstruation Genitourinary 1.27 0.938 – 1.72 0.122 48 486 exclusion phecode
626.12 Excessive or frequent menstruation Genitourinary 1.06 1.02 – 1.09 0.000528 4270 40797 exclusion phecode
626.13 Irregular menstrual cycle Genitourinary 1.07 0.994 – 1.14 0.0729 866 8783 exclusion phecode
626.14 Irregular menstrual bleeding Genitourinary 1.07 1.02 – 1.13 0.00582 1722 16950 exclusion phecode
626.2 Dysmenorrhea Genitourinary 1.2 1.11 – 1.3 2.66e-06 715 8005 exclusion phecode
626.4 Premenstrual tension syndromes Genitourinary 1.19 0.896 – 1.57 0.233 57 690 exclusion phecode
626.8 Infertility, female Genitourinary 1.05 0.963 – 1.13 0.29 646 6174 exclusion phecode
627 Menopausal and postmenopausal disorders Genitourinary 1.03 1 – 1.07 0.0335 4535 44804 exclusion phecode
627.1 Postmenopausal bleeding Genitourinary 1.03 0.999 – 1.07 0.0578 3903 38949 exclusion phecode
627.2 Symptomatic menopause Genitourinary 1 0.795 – 1.26 0.997 77 801 exclusion phecode
627.3 Postmenopausal atrophic vaginitis Genitourinary 1.07 0.981 – 1.17 0.125 540 4725 exclusion phecode
627.4 Premenopausal menorrhagia Genitourinary 0.918 0.767 – 1.1 0.353 140 1391 exclusion phecode
628 Ovarian cyst Genitourinary 1.12 1.07 – 1.17 8.75e-07 2054 21028 exclusion phecode
634 Miscarriage; stillbirth Pregnancy Complications 0.981 0.937 – 1.03 0.398 2172 16790 exclusion phecode
634.1 Missed abortion/Hydatidiform mole Pregnancy Complications 0.876 0.798 – 0.961 0.00527 509 5239 exclusion phecode
634.3 Ectopic pregnancy Pregnancy Complications 0.985 0.826 – 1.18 0.869 136 1530 exclusion phecode
635
Hemorrhage during pregnancy; childbirth and
Hemorrhage during pregnancy; childbirth and postpartum
 Pregnancy Complications 0.927 0.863 – 0.994 0.0343 866 7906 exclusion phecode
635.2
Antepartum hemorrhage, abruptio placentae, and
Antepartum hemorrhage, abruptio placentae, and placenta previa
 Pregnancy Complications 0.939 0.842 – 1.05 0.263 366 3873 exclusion phecode
635.3 Placenta previa and abruptio placenta Pregnancy Complications 0.898 0.824 – 0.98 0.0157 568 5611 exclusion phecode
636
Early or threatened labor; hemorrhage in early
Early or threatened labor; hemorrhage in early pregnancy
 Pregnancy Complications 0.999 0.936 – 1.07 0.987 1027 9077 exclusion phecode
636.2 Early onset of delivery Pregnancy Complications 0.865 0.761 – 0.985 0.0284 267 2801 exclusion phecode
636.3 Hemorrhage in early pregnancy Pregnancy Complications 1.03 0.936 – 1.13 0.542 479 4879 exclusion phecode
638 Other high-risk pregnancy Pregnancy Complications 0.853 0.586 – 1.24 0.406 29 323 exclusion phecode
642
Hypertension complicating pregnancy
Hypertension complicating pregnancy, childbirth, and the puerperium
 Pregnancy Complications 0.98 0.893 – 1.08 0.676 496 5008 exclusion phecode
642.1 Preeclampsia and eclampsia Pregnancy Complications 0.973 0.812 – 1.16 0.762 135 1373 exclusion phecode
643 Excessive vomiting in pregnancy Pregnancy Complications 1.14 0.926 – 1.4 0.216 108 946 exclusion phecode
643.1 Hyperemesis gravidarum Pregnancy Complications 0.996 0.793 – 1.25 0.972 82 666 exclusion phecode
645 Late pregnancy and failed induction Pregnancy Complications 1.03 0.938 – 1.12 0.575 524 5576 exclusion phecode
646 Other complications of pregnancy NEC Pregnancy Complications 1.02 0.954 – 1.09 0.548 930 9386 exclusion phecode
647
Infectious and parasitic complications
Infectious and parasitic complications affecting pregnancy
 Pregnancy Complications 0.827 0.591 – 1.16 0.269 34 303 exclusion phecode
647.1
Infections of genitourinary tract during
Infections of genitourinary tract during pregnancy
 Pregnancy Complications 1.1 0.919 – 1.33 0.292 125 1258 exclusion phecode
649
Other conditions or status of the mother
Other conditions or status of the mother complicating pregnancy, childbirth, or the puerperium
 Pregnancy Complications 0.754 0.555 – 1.02 0.0714 45 497 exclusion phecode
649.1
Diabetes or abnormal glucose tolerance
Diabetes or abnormal glucose tolerance complicating pregnancy
 Pregnancy Complications 1.1 0.887 – 1.37 0.382 94 871 exclusion phecode
650 Normal delivery Pregnancy Complications 0.994 0.927 – 1.07 0.871 856 8476 exclusion phecode
651 Multiple gestation Pregnancy Complications 0.92 0.778 – 1.09 0.331 146 1544 exclusion phecode
652
Malposition and malpresentation of fetus or
Malposition and malpresentation of fetus or obstruction
 Pregnancy Complications 0.928 0.86 – 1 0.05 753 7423 exclusion phecode
653
Problems associated with amniotic cavity and
Problems associated with amniotic cavity and membranes
 Pregnancy Complications 0.881 0.81 – 0.959 0.00325 602 6048 exclusion phecode
654
Other and unspecified complications of birth
Other and unspecified complications of birth; puerperium affecting management of mother
 Pregnancy Complications 0.904 0.627 – 1.3 0.587 29 330 exclusion phecode
655
Known or suspected fetal abnormality affecting
Known or suspected fetal abnormality affecting management of mother
 Pregnancy Complications 0.928 0.883 – 0.975 0.00327 1830 13414 exclusion phecode
656 Other perinatal conditions of fetus or newborn Pregnancy Complications 0.918 0.67 – 1.26 0.593 46 463 exclusion phecode
661 Fetal distress and abnormal forces of labor Pregnancy Complications 0.961 0.898 – 1.03 0.247 956 8419 exclusion phecode
663
Umbilical cord complications during labor and
Umbilical cord complications during labor and delivery
 Pregnancy Complications 0.935 0.817 – 1.07 0.328 236 2370 exclusion phecode
665 Obstetrical/birth trauma Pregnancy Complications 0.937 0.896 – 0.98 0.00439 2389 13511 exclusion phecode
669 Complications of labor and delivery NEC Pregnancy Complications 0.883 0.83 – 0.94 9.85e-05 1114 9615 exclusion phecode
671
Venous/cerebrovascular complications embolism
Venous/cerebrovascular complications embolism in pregnancy and the puerperium
 Pregnancy Complications 1.04 0.807 – 1.34 0.772 66 758 exclusion phecode
674 Other complications of the puerperium NEC Pregnancy Complications 0.945 0.777 – 1.15 0.572 118 1163 exclusion phecode
676
Other disorders of the breast associated with
Other disorders of the breast associated with childbirth and disorders of lactation
 Pregnancy Complications 1.22 0.833 – 1.77 0.312 32 288 exclusion phecode
679 Complications of in utero procedures Dermatologic 0.881 0.618 – 1.26 0.484 31 262 exclusion phecode
681 Superficial cellulitis and abscess Dermatologic 1.04 1 – 1.09 0.0384 2545 27582 exclusion phecode
681.1 Cellulitis and abscess of fingers/toes Dermatologic 1.04 0.909 – 1.2 0.552 221 2086 exclusion phecode
681.2 Cellulitis and abscess of face/neck Dermatologic 0.987 0.847 – 1.15 0.871 177 2094 exclusion phecode
681.3 Cellulitis and abscess of arm/hand Dermatologic 1.04 0.992 – 1.09 0.1 1900 20785 exclusion phecode
681.5 Cellulitis and abscess of leg, except foot Dermatologic 1.04 0.995 – 1.09 0.0779 1911 20789 exclusion phecode
681.6 Cellulitis and abscess of foot, toe Dermatologic 1.04 0.991 – 1.09 0.111 1892 20618 exclusion phecode
681.7 Cellulitis and abscess of trunk Dermatologic 1.12 0.976 – 1.29 0.107 224 2405 exclusion phecode
686
Other local infections of skin and subcutaneous
Other local infections of skin and subcutaneous tissue
 Dermatologic 1.13 1.03 – 1.25 0.0112 472 5198 exclusion phecode
686.1 Carbuncle and furuncle Dermatologic 1.05 0.978 – 1.14 0.166 727 8934 exclusion phecode
686.3 Pilonidal cyst Dermatologic 1.12 0.952 – 1.32 0.174 159 2278 exclusion phecode
686.4 Pyogenic granuloma Dermatologic 1.1 0.934 – 1.28 0.264 162 1378 exclusion phecode
687 Symptoms affecting skin Dermatologic 1.02 0.885 – 1.18 0.777 198 2063 exclusion phecode
687.1 Rash and other nonspecific skin eruption Dermatologic 0.984 0.915 – 1.06 0.668 793 8354 exclusion phecode
687.2 Localized superficial swelling, mass, or lump Dermatologic 1.15 0.943 – 1.4 0.167 105 1090 exclusion phecode
687.3 Changes in skin texture Dermatologic 0.969 0.709 – 1.32 0.842 41 409 exclusion phecode
687.4 Disturbance of skin sensation Dermatologic 1.1 1.04 – 1.17 0.00241 1072 11502 exclusion phecode
689 Disorder of skin and subcutaneous tissue NOS Dermatologic 1.04 0.999 – 1.09 0.0533 2158 22321 exclusion phecode
690 Erythematosquamous dermatosis Dermatologic 1.19 0.779 – 1.82 0.423 22 264 exclusion phecode
690.1 Seborrheic dermatitis Dermatologic 1.4 0.855 – 2.31 0.18 17 196 exclusion phecode
691 Congenital anomalies of skin Dermatologic 1.12 0.855 – 1.48 0.4 50 449 exclusion phecode
694 Dyschromia and Vitiligo Dermatologic 1.06 0.956 – 1.18 0.263 405 3830 exclusion phecode
694.1 Vitiligo Dermatologic 1.35 0.889 – 2.05 0.159 27 240 exclusion phecode
694.2 Other dyschromia Dermatologic 1.04 0.921 – 1.16 0.563 317 3098 exclusion phecode
694.3 Vascular disorders of skin Dermatologic 0.928 0.679 – 1.27 0.64 50 418 exclusion phecode
695 Erythematous conditions Dermatologic 1.06 0.99 – 1.14 0.0939 898 9548 exclusion phecode
695.1 Toxic erythema Dermatologic 1.28 0.909 – 1.79 0.159 36 432 exclusion phecode
695.2 Bullous dermatoses Dermatologic 1.39 1 – 1.92 0.0484 43 518 exclusion phecode
695.21 Dermatitis herpetiformis Dermatologic 0.888 0.525 – 1.5 0.657 15 210 exclusion phecode
695.22 Pemphigus and pemphigoid Dermatologic 1.67 1.09 – 2.55 0.0183 27 293 exclusion phecode
695.3 Rosacea Dermatologic 1.25 1.03 – 1.53 0.0236 119 1177 exclusion phecode
695.4 Lupus (localized and systemic) Dermatologic 0.928 0.787 – 1.09 0.373 159 1766 exclusion phecode
695.41 Cutaneous lupus erythematosus Dermatologic 0.831 0.612 – 1.13 0.234 42 566 exclusion phecode
695.42 Systemic lupus erythematosus Dermatologic 0.958 0.801 – 1.15 0.638 138 1480 exclusion phecode
695.7 Prurigo and Lichen Dermatologic 1.02 0.904 – 1.15 0.766 294 3133 exclusion phecode
695.8 Other specified erythematous conditions Dermatologic 1.24 1 – 1.54 0.0502 91 988 exclusion phecode
695.81 Erythema nodosum Dermatologic 1.07 0.743 – 1.53 0.724 31 314 exclusion phecode
695.9 Unspecified erythematous condition Dermatologic 0.998 0.862 – 1.16 0.981 188 1805 exclusion phecode
696 Psoriasis and related disorders Dermatologic 1 0.922 – 1.08 0.991 647 8661 exclusion phecode
696.4 Psoriasis Dermatologic 0.994 0.916 – 1.08 0.885 633 8471 exclusion phecode
696.41 Psoriasis vulgaris Dermatologic 1.01 0.915 – 1.11 0.872 442 6443 exclusion phecode
696.42 Psoriatic arthropathy Dermatologic 1.02 0.896 – 1.17 0.733 242 2783 exclusion phecode
697 Sarcoidosis Dermatologic 1.04 0.911 – 1.18 0.595 259 2129 exclusion phecode
698 Pruritus and related conditions Dermatologic 1.05 0.927 – 1.18 0.46 286 3056 exclusion phecode
700 Corns and callosities Dermatologic 1.24 1.01 – 1.52 0.0418 99 1234 exclusion phecode
701
Other hypertrophic and atrophic conditions of
Other hypertrophic and atrophic conditions of skin
 Dermatologic 1.05 0.995 – 1.1 0.0782 1752 18530 exclusion phecode
701.1 Keratoderma, acquired Dermatologic 0.867 0.613 – 1.23 0.42 33 330 exclusion phecode
701.2 Scar conditions and fibrosis of skin Dermatologic 1.06 0.992 – 1.14 0.0837 886 9336 exclusion phecode
701.3 Circumscribed scleroderma Dermatologic 0.994 0.623 – 1.59 0.979 17 270 exclusion phecode
701.4 Keloid scar Dermatologic 1.14 0.909 – 1.43 0.257 85 928 exclusion phecode
701.5 Abnormal granulation tissue Dermatologic 1.03 0.88 – 1.19 0.75 185 1830 exclusion phecode
701.6 Acquired acanthosis nigricans Dermatologic 1.5 1.06 – 2.12 0.0219 37 376 exclusion phecode
702
Degenerative skin conditions and other
Degenerative skin conditions and other dermatoses
 Dermatologic 0.99 0.946 – 1.04 0.662 2092 20624 exclusion phecode
702.1 Actinic keratosis Dermatologic 0.993 0.929 – 1.06 0.847 993 9713 exclusion phecode
702.2 Seborrheic keratosis Dermatologic 0.991 0.934 – 1.05 0.77 1175 11627 exclusion phecode
703 Diseases of nail, NOS Dermatologic 1.02 0.85 – 1.23 0.819 130 1371 exclusion phecode
703.1 Ingrowing nail Dermatologic 1.04 0.935 – 1.15 0.483 378 3807 exclusion phecode
704 Diseases of hair and hair follicles Dermatologic 1.06 1.01 – 1.11 0.0134 1865 20586 exclusion phecode
704.1 Alopecia Dermatologic 0.948 0.728 – 1.23 0.691 54 524 exclusion phecode
704.8
Other specified diseases of hair and hair
Other specified diseases of hair and hair follicles
 Dermatologic 1.22 0.845 – 1.77 0.288 32 296 exclusion phecode
705 Disorders of sweat glands Dermatologic 1.03 0.746 – 1.42 0.857 38 979 exclusion phecode
705.3 Hidradenitis Dermatologic 0.989 0.678 – 1.44 0.956 26 810 exclusion phecode
705.8 Hyperhidrosis Dermatologic 1.08 0.936 – 1.24 0.295 198 2246 exclusion phecode
706 Diseases of sebaceous glands Dermatologic 1.06 1.02 – 1.1 0.00377 2890 32610 exclusion phecode
706.1 Acne Dermatologic 1.29 0.898 – 1.84 0.169 30 307 exclusion phecode
706.2 Sebaceous cyst Dermatologic 1.05 1.01 – 1.09 0.0076 3065 34439 exclusion phecode
707 Chronic ulcer of skin Dermatologic 1.03 0.95 – 1.12 0.443 606 7266 exclusion phecode
707.1 Decubitus ulcer Dermatologic 1.12 0.989 – 1.28 0.0732 264 3340 exclusion phecode
709 Diffuse diseases of connective tissue Dermatologic 1.11 1.04 – 1.17 0.000726 1302 13710 exclusion phecode
709.2 Sicca syndrome Dermatologic 1.1 0.954 – 1.27 0.189 223 2097 exclusion phecode
709.3 Systemic sclerosis Dermatologic 0.92 0.713 – 1.19 0.523 66 738 exclusion phecode
709.6
Other specified diffuse diseases of connective
Other specified diffuse diseases of connective tissue
 Dermatologic 0.906 0.63 – 1.3 0.595 29 278 exclusion phecode
709.7 Unspecified diffuse connective tissue disease Dermatologic 1.11 1.04 – 1.19 0.00196 1010 10791 exclusion phecode
710
Osteomyelitis, periostitis, and other
Osteomyelitis, periostitis, and other infections involving bone
 Musculoskeletal 1.13 0.969 – 1.31 0.12 186 2243 exclusion phecode
710.1 Osteomyelitis Musculoskeletal 1.13 0.971 – 1.32 0.114 175 2070 exclusion phecode
710.12 Chronic osteomyelitis Musculoskeletal 1.15 0.879 – 1.49 0.315 58 718 exclusion phecode
710.19 Unspecified osteomyelitis Musculoskeletal 1.14 0.954 – 1.37 0.147 131 1469 exclusion phecode
711 Arthropathy associated with infections Musculoskeletal 1.06 0.897 – 1.25 0.503 163 1549 exclusion phecode
711.1 Pyogenic arthritis Musculoskeletal 1.2 0.999 – 1.45 0.0516 122 1217 exclusion phecode
712 Infective connective tissue disorders Musculoskeletal 1.29 0.892 – 1.85 0.177 26 304 exclusion phecode
713
Arthropathy associated with other disorders
Arthropathy associated with other disorders classified elsewhere
 Musculoskeletal 1.05 0.793 – 1.38 0.746 53 560 exclusion phecode
713.5
Arthropathy associated with neurological
Arthropathy associated with neurological disorders
 Musculoskeletal 1.13 0.711 – 1.8 0.602 19 231 exclusion phecode
714
Rheumatoid arthritis and other inflammatory
Rheumatoid arthritis and other inflammatory polyarthropathies
 Musculoskeletal 1.1 1.04 – 1.16 0.000318 1625 19767 exclusion phecode
714.1 Rheumatoid arthritis Musculoskeletal 1.1 1.05 – 1.16 0.000281 1473 17976 exclusion phecode
715 Other inflammatory spondylopathies Musculoskeletal 1.14 1.04 – 1.24 0.00331 545 6510 exclusion phecode
715.1 Sacroiliitis NEC Musculoskeletal 1.14 0.86 – 1.5 0.371 53 472 exclusion phecode
715.2 Ankylosing spondylitis Musculoskeletal 1.01 0.871 – 1.18 0.85 182 2337 exclusion phecode
716 Other arthropathies Musculoskeletal 1.12 1.1 – 1.14 2.72e-32 13471 104203 exclusion phecode
716.1 Unspecified polyarthropathy or polyarthritis Musculoskeletal 1.16 1.09 – 1.23 6.29e-07 1280 13847 exclusion phecode
716.2 Unspecified monoarthritis Musculoskeletal 1.12 1.09 – 1.15 8.33e-17 5767 59651 exclusion phecode
716.9 Arthropathy NOS Musculoskeletal 1.12 1.1 – 1.14 1.85e-32 12913 102877 exclusion phecode
717 Polymyalgia Rheumatica Musculoskeletal 1.04 0.937 – 1.15 0.473 413 4392 exclusion phecode
720 Spinal stenosis Musculoskeletal 1.15 1.08 – 1.22 7.05e-06 1202 14119 exclusion phecode
721 Spondylosis and allied disorders Musculoskeletal 1.14 1.1 – 1.19 3.39e-11 2752 30772 exclusion phecode
721.1 Spondylosis without myelopathy Musculoskeletal 1.13 1.08 – 1.19 7.79e-07 1745 19836 exclusion phecode
721.2 Spondylosis with myelopathy Musculoskeletal 1.23 0.949 – 1.6 0.117 54 736 exclusion phecode
721.8 Other allied disorders of spine Musculoskeletal 0.999 0.834 – 1.2 0.992 132 1342 exclusion phecode
722 Intervertebral disc disorders Musculoskeletal 1.15 1.11 – 1.19 2.28e-13 3159 35831 exclusion phecode
722.1 Displacement of intervertebral disc Musculoskeletal 1.2 1.03 – 1.4 0.0223 173 2021 exclusion phecode
722.6 Degeneration of intervertebral disc Musculoskeletal 1.19 1.12 – 1.27 1.57e-07 1000 11396 exclusion phecode
722.8 Postlaminectomy syndrome Musculoskeletal 1.28 0.812 – 2.03 0.286 17 288 exclusion phecode
722.9 Other and unspecified disc disorder Musculoskeletal 1.1 1.05 – 1.16 0.000245 1553 17536 exclusion phecode
723 Other disorders of cervical region Musculoskeletal 1.02 0.869 – 1.2 0.799 161 2044 exclusion phecode
723.1 Torticollis Musculoskeletal 0.971 0.712 – 1.33 0.855 44 472 exclusion phecode
724 Other and unspecified disorders of back Musculoskeletal 1.06 0.985 – 1.15 0.118 727 7997 exclusion phecode
724.1 Disorders of sacrum Musculoskeletal 1.04 0.874 – 1.23 0.682 145 1713 exclusion phecode
724.2 Disorders of coccyx Musculoskeletal 1.04 0.88 – 1.23 0.634 148 1728 exclusion phecode
724.8 Other symptoms referable to back Musculoskeletal 1.04 0.675 – 1.6 0.867 18 240 exclusion phecode
724.9 Other unspecified back disorders Musculoskeletal 1.07 0.981 – 1.17 0.126 574 6160 exclusion phecode
726 Peripheral enthesopathies and allied syndromes Musculoskeletal 1.08 1.05 – 1.11 4.92e-08 5434 57467 exclusion phecode
726.1 Enthesopathy Musculoskeletal 1.06 1.02 – 1.1 0.00144 3603 37547 exclusion phecode
726.2 Synoviopathy Musculoskeletal 1.22 1.02 – 1.47 0.0325 123 1349 exclusion phecode
726.3 Bursitis Musculoskeletal 1.13 1.01 – 1.28 0.0359 314 3090 exclusion phecode
727 Other disorders of synovium, tendon, and bursa Musculoskeletal 1.1 1.06 – 1.14 2.6e-06 2775 29333 exclusion phecode
727.1 Synovitis and tenosynovitis Musculoskeletal 1.14 1.07 – 1.21 7.64e-05 1031 10956 exclusion phecode
727.2 Bursitis disorders Musculoskeletal 1.04 0.739 – 1.45 0.836 35 390 exclusion phecode
727.4 Ganglion and cyst of synovium, tendon, and bursa Musculoskeletal 1.1 1.04 – 1.17 0.00158 1205 12612 exclusion phecode
727.5 Rupture of synovium Musculoskeletal 0.998 0.866 – 1.15 0.983 205 2262 exclusion phecode
727.6 Rupture of tendon, nontraumatic Musculoskeletal 1.1 0.926 – 1.31 0.272 137 1345 exclusion phecode
727.7 Contracture of tendon (sheath) Musculoskeletal 0.951 0.718 – 1.26 0.723 48 524 exclusion phecode
728 Disorders of muscle, ligament, and fascia Musculoskeletal 1.03 0.967 – 1.09 0.374 1143 12648 exclusion phecode
728.2 Laxity of ligament or hypermobility syndrome Musculoskeletal 0.955 0.813 – 1.12 0.579 159 1690 exclusion phecode
728.7 Fasciitis Musculoskeletal 1.02 0.962 – 1.08 0.504 1208 13193 exclusion phecode
728.71
Contracture of palmar fascia [Dupuytren's
Contracture of palmar fascia [Dupuytren's disease]
 Musculoskeletal 1.01 0.952 – 1.08 0.667 1068 11886 exclusion phecode
729 Other disorders of soft tissues Musculoskeletal 1.07 1.03 – 1.12 0.00208 2239 23837 exclusion phecode
729.1 Rheumatism, unspecified and fibrositis Musculoskeletal 1.07 0.961 – 1.19 0.223 389 4240 exclusion phecode
729.3 Panniculitis Musculoskeletal 1.37 0.994 – 1.89 0.0543 37 423 exclusion phecode
731
Osteitis deformans and osteopathies associated
Osteitis deformans and osteopathies associated with other disorders classified elsewhere
 Musculoskeletal 1.13 0.945 – 1.36 0.175 126 1116 exclusion phecode
731.1 Osteitis deformans [Paget's disease of bone] Musculoskeletal 1.16 0.965 – 1.4 0.114 121 1076 exclusion phecode
732 Osteochondropathies Musculoskeletal 1 0.857 – 1.18 0.961 176 1853 exclusion phecode
732.1 Juvenile osteochondrosis Musculoskeletal 1 0.8 – 1.26 0.973 78 826 exclusion phecode
732.7 Osteochondritis dissecans Musculoskeletal 0.978 0.66 – 1.45 0.912 27 219 exclusion phecode
733 Other disorders of bone and cartilage Musculoskeletal 1.11 1.03 – 1.2 0.0095 669 7299 exclusion phecode
733.2 Cyst of bone Musculoskeletal 1.1 0.911 – 1.33 0.318 118 1300 exclusion phecode
733.4 Aseptic necrosis of bone Musculoskeletal 1.05 0.903 – 1.22 0.538 187 2143 exclusion phecode
733.6 Costochondritis Musculoskeletal 0.989 0.75 – 1.3 0.936 46 517 exclusion phecode
733.8 Malunion and nonunion of fracture Musculoskeletal 1.1 0.997 – 1.22 0.0565 430 4857 exclusion phecode
733.9 Chondromalacia Musculoskeletal 1.21 0.892 – 1.64 0.221 43 498 exclusion phecode
735 Acquired foot deformities Musculoskeletal 1.09 1.05 – 1.12 1.12e-06 3933 39935 exclusion phecode
735.1 Flat foot Musculoskeletal 1.3 0.999 – 1.7 0.0509 61 765 exclusion phecode
735.2 Acquired toe deformities Musculoskeletal 1.08 1.03 – 1.13 0.00178 2042 20855 exclusion phecode
735.21 Hammer toe (acquired) Musculoskeletal 1.03 0.954 – 1.1 0.489 796 8045 exclusion phecode
735.23 Hallux rigidus Musculoskeletal 1.07 0.982 – 1.16 0.126 643 6181 exclusion phecode
735.3 Hallux valgus (Bunion) Musculoskeletal 1.09 1.04 – 1.13 4.55e-05 2803 28016 exclusion phecode
736 Other acquired deformities of limbs Musculoskeletal 1.04 0.952 – 1.13 0.407 569 6306 exclusion phecode
736.2 Acquired deformities of finger Musculoskeletal 0.925 0.753 – 1.14 0.46 88 934 exclusion phecode
737 Curvature of spine Musculoskeletal 1.04 0.94 – 1.15 0.456 417 4618 exclusion phecode
737.3 Kyphoscoliosis and scoliosis Musculoskeletal 1.03 0.933 – 1.15 0.52 388 4350 exclusion phecode
738 Other acquired musculoskeletal deformity Musculoskeletal 1.14 1.05 – 1.24 0.00137 653 7667 exclusion phecode
738.4 Acquired spondylolisthesis Musculoskeletal 1.13 1.03 – 1.24 0.00707 518 6111 exclusion phecode
739 Contracture of joint Musculoskeletal 1.06 0.903 – 1.24 0.479 173 1923 exclusion phecode
740 Osteoarthrosis Musculoskeletal 1.11 1.08 – 1.13 4.57e-21 10043 89432 exclusion phecode
740.1 Osteoarthritis; localized Musculoskeletal 1.08 1.05 – 1.11 1.63e-09 6479 65025 exclusion phecode
740.11 Osteoarthrosis, localized, primary Musculoskeletal 1.07 1.03 – 1.11 0.000153 3380 34356 exclusion phecode
740.12 Osteoarthrosis, localized, secondary Musculoskeletal 1.14 0.956 – 1.37 0.142 129 1337 exclusion phecode
740.2 Osteoarthrosis, generalized Musculoskeletal 1.24 1.08 – 1.43 0.00259 231 2309 exclusion phecode
740.9 Osteoarthrosis NOS Musculoskeletal 1.15 1.11 – 1.19 3.8e-18 4279 48128 exclusion phecode
741 Symptoms and disorders of the joints Musculoskeletal 1.07 1.01 – 1.13 0.0154 1391 13747 exclusion phecode
741.1 Ankylosis of joint Musculoskeletal 1.1 0.758 – 1.59 0.62 35 389 exclusion phecode
741.2 Stiffness of joint Musculoskeletal 1.05 0.927 – 1.2 0.42 253 2466 exclusion phecode
741.3 Difficulty in walking Musculoskeletal 0.889 0.681 – 1.16 0.386 59 562 exclusion phecode
741.4 Joint effusions Musculoskeletal 1.11 1.02 – 1.22 0.0146 560 5307 exclusion phecode
741.5 Hemarthrosis Musculoskeletal 0.97 0.696 – 1.35 0.858 35 417 exclusion phecode
741.6 Villonodular synovitis Musculoskeletal 0.829 0.552 – 1.25 0.367 20 233 exclusion phecode
742 Derangement of joint, non-traumatic Musculoskeletal 1.11 1.05 – 1.18 0.000694 1160 11432 exclusion phecode
742.1 Loose body in joint Musculoskeletal 1.13 0.939 – 1.36 0.197 123 1240 exclusion phecode
742.2
Pathological, developmental or recurrent
Pathological, developmental or recurrent dislocation
 Musculoskeletal 0.962 0.72 – 1.29 0.794 47 391 exclusion phecode
742.8 Articular cartilage disorder Musculoskeletal 1.1 0.953 – 1.27 0.192 208 1981 exclusion phecode
742.9 Other derangement of joint Musculoskeletal 1.11 1.04 – 1.2 0.00364 815 8075 exclusion phecode
743
Osteoporosis, osteopenia and pathological
Osteoporosis, osteopenia and pathological fracture
 Musculoskeletal 1.02 0.984 – 1.06 0.261 2902 30691 exclusion phecode
743.1 Osteoporosis Musculoskeletal 0.997 0.957 – 1.04 0.905 2459 26114 exclusion phecode
743.11 Osteoporosis NOS Musculoskeletal 0.998 0.955 – 1.04 0.924 2180 22971 exclusion phecode
743.13 Other specified osteoporosis Musculoskeletal 0.89 0.758 – 1.04 0.153 167 1943 exclusion phecode
743.2 Pathologic fracture Musculoskeletal 1.06 0.898 – 1.25 0.504 156 1992 exclusion phecode
743.9
Osteopenia or other disorder of bone and
Osteopenia or other disorder of bone and cartilage
 Musculoskeletal 1.15 1.03 – 1.29 0.0131 337 3251 exclusion phecode
745 Pain in joint Musculoskeletal 1.15 1.11 – 1.19 5.45e-13 3060 31484 exclusion phecode
747 Cardiac and circulatory congenital anomalies Congenital Anomalies 1.02 0.95 – 1.09 0.633 908 10328 exclusion phecode
747.1 Cardiac congenital anomalies Congenital Anomalies 1 0.936 – 1.08 0.893 842 9660 exclusion phecode
747.11 Cardiac shunt/ heart septal defect Congenital Anomalies 0.934 0.818 – 1.07 0.307 238 2325 exclusion phecode
747.12 Valvular heart disease/ heart chambers Congenital Anomalies 0.975 0.771 – 1.23 0.836 81 869 exclusion phecode
747.13 Congenital anomalies of great vessels Congenital Anomalies 1.03 0.938 – 1.12 0.574 522 6446 exclusion phecode
747.2
Congenital anomalies of peripheral vascular
Congenital anomalies of peripheral vascular system
 Congenital Anomalies 1.08 0.84 – 1.4 0.533 66 625 exclusion phecode
748 Anomalies of respiratory system, congenital Congenital Anomalies 1.31 0.864 – 1.98 0.204 22 177 exclusion phecode
749 Congenital anomalies of face and neck Congenital Anomalies 1.05 0.869 – 1.27 0.617 110 1216 exclusion phecode
750 Digestive congenital anomalies Congenital Anomalies 0.893 0.784 – 1.02 0.0867 254 2545 exclusion phecode
750.1 Upper gastrointestinal congenital anomalies Congenital Anomalies 0.876 0.724 – 1.06 0.172 114 1179 exclusion phecode
750.13 Congenital anomalies of mouth/tongue Congenital Anomalies 0.81 0.632 – 1.04 0.0972 70 673 exclusion phecode
750.2 Lower gastrointestinal congenital anomalies Congenital Anomalies 0.888 0.745 – 1.06 0.183 139 1384 exclusion phecode
750.21 Congenital anomalies of intestine Congenital Anomalies 0.794 0.635 – 0.991 0.0413 83 871 exclusion phecode
750.22
Congenital anomaly of gallbladder, bile ducts
Congenital anomaly of gallbladder, bile ducts, liver, pancreas
 Congenital Anomalies 1.09 0.812 – 1.47 0.561 54 465 exclusion phecode
751 Genitourinary congenital anomalies Congenital Anomalies 1.05 0.96 – 1.14 0.305 587 6051 exclusion phecode
751.1 Congenital anomalies of genital organs Congenital Anomalies 1.03 0.909 – 1.16 0.684 289 2881 exclusion phecode
751.11 Congenital anomalies of female genital organs Congenital Anomalies 1.07 0.928 – 1.23 0.363 215 2025 exclusion phecode
751.12 Congenital anomalies of male genital organs Congenital Anomalies 0.889 0.679 – 1.16 0.392 62 741 exclusion phecode
751.2 Congenital anomalies of urinary system Congenital Anomalies 1.11 0.984 – 1.25 0.0905 302 3186 exclusion phecode
751.21 Cystic kidney disease Congenital Anomalies 1.1 0.927 – 1.3 0.279 153 1605 exclusion phecode
751.22 Other specified congenital anomalies of kidney Congenital Anomalies 1.17 0.966 – 1.42 0.107 115 1281 exclusion phecode
752 Nervous system congenital anomalies Congenital Anomalies 1.09 0.917 – 1.29 0.331 141 1361 exclusion phecode
752.1 Neural tube defects Congenital Anomalies 1.05 0.872 – 1.27 0.592 110 1063 exclusion phecode
752.11 Spina bifida Congenital Anomalies 1.13 0.908 – 1.4 0.281 86 873 exclusion phecode
752.2
Other specified congenital anomalies of nervous
Other specified congenital anomalies of nervous system
 Congenital Anomalies 1.02 0.71 – 1.48 0.9 33 326 exclusion phecode
753 Congenital anomalies of the eye Congenital Anomalies 1.05 0.784 – 1.42 0.728 54 511 exclusion phecode
753.1 Congenital cataract and lens anomalies Congenital Anomalies 1.08 0.743 – 1.56 0.698 33 309 exclusion phecode
754 Congenital musculoskeletal deformities of spine Congenital Anomalies 1.38 1.01 – 1.87 0.0417 47 459 exclusion phecode
755 Congenital anomalies of limbs Congenital Anomalies 1.07 0.919 – 1.25 0.384 173 1730 exclusion phecode
755.1 Congenital deformities of feet Congenital Anomalies 0.972 0.774 – 1.22 0.808 77 838 exclusion phecode
755.6
Other congenital anomalies of lower limb
Other congenital anomalies of lower limb, including pelvic girdle
 Congenital Anomalies 1.35 1.05 – 1.74 0.0211 69 687 exclusion phecode
755.61 Congenital hip dysplasia and deformity Congenital Anomalies 1.3 0.948 – 1.77 0.104 46 469 exclusion phecode
756 Other congenital musculoskeletal anomalies Congenital Anomalies 1.18 1.02 – 1.35 0.0221 211 2416 exclusion phecode
756.3
Congenital anomalies of muscle, tendon, fascia
Congenital anomalies of muscle, tendon, fascia, and connective tissue
 Congenital Anomalies 1.75 1.23 – 2.49 0.00201 33 339 exclusion phecode
756.5 Congenital osteodystrophies Congenital Anomalies 1.14 0.964 – 1.34 0.126 146 1804 exclusion phecode
758 Chromosomal anomalies and genetic disorders Congenital Anomalies 1.1 0.85 – 1.44 0.456 58 672 exclusion phecode
758.1 Chromosomal anomalies Congenital Anomalies 1.69 1.11 – 2.57 0.0143 23 353 exclusion phecode
759 Other and unspecified congenital anomalies Congenital Anomalies 0.997 0.801 – 1.24 0.982 81 871 exclusion phecode
759.1 Anomalies of endocrine glands, congenital Congenital Anomalies 0.799 0.555 – 1.15 0.228 29 372 exclusion phecode
760 Back pain Symptoms 1.11 1.07 – 1.14 2.57e-09 3906 44171 exclusion phecode
761 Cervicalgia Symptoms 1.13 1.04 – 1.22 0.00455 654 7129 exclusion phecode
764 Sciatica Symptoms 1.11 1.03 – 1.19 0.00628 788 9411 exclusion phecode
766 Neuralgia, neuritis, and radiculitis NOS Symptoms 1.12 1.01 – 1.24 0.0246 413 4651 exclusion phecode
770 Myalgia and myositis unspecified Symptoms 1.04 0.922 – 1.18 0.492 259 2489 exclusion phecode
771 Musculoskeletal symptoms referable to limbs Symptoms 1.06 0.947 – 1.18 0.318 334 3411 exclusion phecode
771.1 Swelling of limb Symptoms 1.08 1.03 – 1.13 0.00331 1697 17920 exclusion phecode
772 Symptoms of the muscles Symptoms 0.949 0.832 – 1.08 0.436 240 2451 exclusion phecode
773 Pain in limb Symptoms 1.12 1.07 – 1.17 2.38e-07 2318 24753 exclusion phecode
780 Hypothermia/Chills Symptoms 1.09 0.831 – 1.43 0.529 57 612 exclusion phecode
781
Symptoms involving nervous and musculoskeletal
Symptoms involving nervous and musculoskeletal systems
 Symptoms 1.15 1.06 – 1.25 0.000506 655 7342 exclusion phecode
782.3 Edema Symptoms 1.05 0.961 – 1.14 0.284 555 6168 exclusion phecode
782.6 Pallor and flushing Symptoms 1.39 1.05 – 1.84 0.0228 49 668 exclusion phecode
783 Fever of unknown origin Symptoms 1.04 0.984 – 1.1 0.164 1474 14920 exclusion phecode
785 Abdominal pain Symptoms 1.07 1.06 – 1.09 1.05e-16 15218 119213 exclusion phecode
788 Syncope and collapse Symptoms 1.04 0.999 – 1.07 0.0562 3392 33887 exclusion phecode
789 Nausea and vomiting Symptoms 1.06 1.03 – 1.09 0.000282 4367 46345 exclusion phecode
790 Nonspecific findings on examination of blood Symptoms 0.727 0.548 – 0.964 0.027 51 560 exclusion phecode
790.1 Elevated sedimentation rate Symptoms 1.08 0.758 – 1.55 0.662 30 297 exclusion phecode
790.6 Other abnormal blood chemistry Symptoms 1.05 1.01 – 1.1 0.0261 2172 21736 exclusion phecode
791 Gangrene Symptoms 0.98 0.841 – 1.14 0.79 182 2012 exclusion phecode
792
Abnormal Papanicolaou smear of cervix and
Abnormal Papanicolaou smear of cervix and cervical HPV
 Symptoms 0.795 0.533 – 1.19 0.26 24 388 exclusion phecode
793
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of musculoskeletal system
 Symptoms 1.03 0.758 – 1.41 0.829 38 505 exclusion phecode
793.2
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of other intrathoracic organs (echocardiogram, etc)
 Symptoms 0.936 0.807 – 1.08 0.377 192 2109 exclusion phecode
794
Abnormal results of other function studies
Abnormal results of other function studies (bladder, pancreas, placenta, spleen, etc)
 Symptoms 0.729 0.547 – 0.97 0.03 50 531 exclusion phecode
797 Shock Symptoms 1.2 0.917 – 1.57 0.183 55 533 exclusion phecode
797.1 Cardiogenic shock Symptoms 1.34 0.985 – 1.83 0.0626 38 346 exclusion phecode
798 Malaise and fatigue Symptoms 1.03 0.97 – 1.09 0.366 1293 13469 exclusion phecode
798.1 Chronic fatigue syndrome Symptoms 0.951 0.834 – 1.08 0.452 247 2477 exclusion phecode
800 Fracture of lower limb Injuries & Poisonings 1.06 1.02 – 1.1 0.00548 2553 28012 exclusion phecode
800.1 Fracture of neck of femur Injuries & Poisonings 1 0.923 – 1.09 0.971 636 7147 exclusion phecode
800.2 Fracture of unspecified part of femur Injuries & Poisonings 1.2 0.917 – 1.57 0.185 58 667 exclusion phecode
800.3 Fracture of tibia and fibula Injuries & Poisonings 1.09 1.01 – 1.17 0.0246 776 8454 exclusion phecode
800.4 Fracture of patella Injuries & Poisonings 0.962 0.849 – 1.09 0.54 271 2943 exclusion phecode
801 Fracture of ankle and foot Injuries & Poisonings 1.1 1.02 – 1.18 0.0139 762 8691 exclusion phecode
801.1 Fracture of foot Injuries & Poisonings 1.1 1.01 – 1.19 0.0257 645 7213 exclusion phecode
802 Fracture of pelvis Injuries & Poisonings 1.15 1.01 – 1.3 0.0372 259 2686 exclusion phecode
803 Fracture of upper limb Injuries & Poisonings 1.03 0.995 – 1.07 0.093 3337 33262 exclusion phecode
803.1 Fracture of humerus Injuries & Poisonings 1.02 0.938 – 1.1 0.687 652 6847 exclusion phecode
803.2 Fracture of radius and ulna Injuries & Poisonings 1.01 0.965 – 1.05 0.701 2200 21366 exclusion phecode
803.3 Fracture of clavicle or scapula Injuries & Poisonings 1.16 1.06 – 1.26 0.00118 534 5628 exclusion phecode
804 Fracture of hand or wrist Injuries & Poisonings 1.06 1 – 1.13 0.0395 1294 13060 exclusion phecode
805
Fracture of vertebral column without mention of
Fracture of vertebral column without mention of spinal cord injury
 Injuries & Poisonings 0.977 0.891 – 1.07 0.628 482 4949 exclusion phecode
807 Fracture of ribs Injuries & Poisonings 1.35 1.18 – 1.54 7.74e-06 252 2909 exclusion phecode
809 Fracture of unspecified bones Injuries & Poisonings 0.996 0.909 – 1.09 0.93 502 4854 exclusion phecode
817 Concussion Injuries & Poisonings 1.06 0.864 – 1.3 0.58 103 910 exclusion phecode
818 Intracranial hemorrhage (injury) Injuries & Poisonings 1.09 0.936 – 1.28 0.259 174 1792 exclusion phecode
819
Skull and face fracture and other intercranial
Skull and face fracture and other intercranial injury
 Injuries & Poisonings 1.1 1.03 – 1.17 0.0043 1071 11468 exclusion phecode
823 Torus fracture Injuries & Poisonings 1.13 1.04 – 1.23 0.0044 589 6511 exclusion phecode
830 Dislocation Injuries & Poisonings 1.15 1.07 – 1.24 0.00024 790 8174 exclusion phecode
835 Internal derangement of knee Injuries & Poisonings 1.08 1.06 – 1.11 5.16e-09 5816 58512 exclusion phecode
836 Traumatic arthropathy Injuries & Poisonings 1.32 1.13 – 1.54 0.000319 185 2059 exclusion phecode
840 Sprains and strains Injuries & Poisonings 1.07 0.917 – 1.24 0.403 188 1820 exclusion phecode
850 Hemorrhage or hematoma complicating a procedure Injuries & Poisonings 1.03 0.979 – 1.08 0.274 1942 20246 exclusion phecode
851
Complications of transplants and reattached
Complications of transplants and reattached limbs
 Injuries & Poisonings 1.17 0.905 – 1.51 0.232 64 596 exclusion phecode
853 Complication of colostomy or enterostomy Injuries & Poisonings 0.978 0.833 – 1.15 0.79 165 1925 exclusion phecode
854
Complications of cardiac/vascular device
Complications of cardiac/vascular device, implant, and graft
 Injuries & Poisonings 1.06 0.965 – 1.16 0.226 491 6457 exclusion phecode
857
Mechanical complication of unspecified
Mechanical complication of unspecified genitourinary device, implant, and graft
 Injuries & Poisonings 1.1 0.993 – 1.21 0.0676 432 4683 exclusion phecode
858 Complication of internal orthopedic device Injuries & Poisonings 1.14 1.07 – 1.21 3.36e-05 1189 12339 exclusion phecode
859
Complication due to other implant and internal
Complication due to other implant and internal device
 Injuries & Poisonings 1.15 1.09 – 1.22 2.75e-06 1209 12868 exclusion phecode
860 Bone marrow or stem cell transplant Neoplasms 0.791 0.549 – 1.14 0.206 31 257 exclusion phecode
870 Open wounds of head; neck; and trunk Injuries & Poisonings 1.18 1.11 – 1.25 8.05e-08 1174 13118 exclusion phecode
870.1 Open wound or laceration of eye or eyelid Injuries & Poisonings 1.01 0.816 – 1.25 0.915 93 1078 exclusion phecode
870.2 Open wound of ear Injuries & Poisonings 1.2 0.947 – 1.53 0.129 74 730 exclusion phecode
870.3 Other open wound of head and face Injuries & Poisonings 1.18 1.11 – 1.26 5.73e-07 986 10830 exclusion phecode
870.4 Open wound of nose and sinus Injuries & Poisonings 1.2 0.939 – 1.52 0.148 74 817 exclusion phecode
870.6 Open wound of neck Injuries & Poisonings 0.915 0.6 – 1.4 0.681 20 252 exclusion phecode
871 Open wounds of extremities Injuries & Poisonings 1.12 1.06 – 1.19 6.39e-05 1327 15540 exclusion phecode
871.1 Open wound of hand except finger(s) Injuries & Poisonings 1.5 0.961 – 2.34 0.0743 17 201 exclusion phecode
871.2 Open wound of finger(s) Injuries & Poisonings 1.28 0.86 – 1.91 0.223 28 303 exclusion phecode
871.3 Open wound of foot except toe(s) alone Injuries & Poisonings 1.27 0.956 – 1.68 0.0993 52 662 exclusion phecode
872 Traumatic amputation Injuries & Poisonings 0.998 0.84 – 1.19 0.981 146 1725 exclusion phecode
873 Broken tooth Injuries & Poisonings 1.01 0.816 – 1.24 0.949 94 909 exclusion phecode
874 Complication of amputation stump Injuries & Poisonings 1.48 1.1 – 2 0.0105 44 629 exclusion phecode
905
Late effects of musculoskeletal and connective
Late effects of musculoskeletal and connective tissue injuries
 Injuries & Poisonings 1.15 0.878 – 1.51 0.308 59 597 exclusion phecode
907 Injuries to the nervous system Injuries & Poisonings 1.13 1.02 – 1.24 0.0175 441 4971 exclusion phecode
915 Superficial injury without mention of infection Injuries & Poisonings 1.1 1.04 – 1.16 0.000493 1515 16443 exclusion phecode
916 Contusion Injuries & Poisonings 1.14 1.04 – 1.24 0.0054 544 5641 exclusion phecode
930 Allergic reaction to food Injuries & Poisonings 0.987 0.752 – 1.3 0.927 56 764 exclusion phecode
938 Dermatitis due to solar radiation Injuries & Poisonings 0.961 0.808 – 1.14 0.653 143 1383 exclusion phecode
938.2 Chronic dermatitis due to solar radiation Injuries & Poisonings 0.922 0.75 – 1.13 0.441 96 889 exclusion phecode
939
Atopic/contact dermatitis due to other or
Atopic/contact dermatitis due to other or unspecified
 Dermatologic 0.928 0.862 – 0.999 0.0466 777 8217 exclusion phecode
941 Adverse reaction to serum or vaccine Injuries & Poisonings 0.879 0.684 – 1.13 0.316 67 889 exclusion phecode
942 Infusion and transfusion reaction Injuries & Poisonings 1.02 0.753 – 1.38 0.901 52 405 exclusion phecode
946 Anaphylactic shock NOS Injuries & Poisonings 1.2 1.02 – 1.41 0.0282 160 2137 exclusion phecode
947 Urticaria Injuries & Poisonings 1 0.841 – 1.19 0.981 141 1445 exclusion phecode
949 Allergies, other Injuries & Poisonings 1.14 0.96 – 1.35 0.137 155 1617 exclusion phecode
952
Spinal cord injury without evidence of spinal
Spinal cord injury without evidence of spinal bone injury
 Injuries & Poisonings 1.06 0.899 – 1.25 0.485 154 1528 exclusion phecode
957 Injury to other and unspecified nerves Injuries & Poisonings 1.09 0.872 – 1.37 0.445 81 988 exclusion phecode
958
Certain early complications of trauma or
Certain early complications of trauma or procedure
 Injuries & Poisonings 1.08 0.926 – 1.25 0.337 176 1899 exclusion phecode
958.1 Postoperative shock Injuries & Poisonings 0.95 0.626 – 1.44 0.809 21 212 exclusion phecode
958.2 Traumatic and surgical subcutaneous emphysema Injuries & Poisonings 1.1 0.75 – 1.63 0.617 25 259 exclusion phecode
960 Poisoning by antibiotics Injuries & Poisonings 1.04 1.01 – 1.06 0.00285 6836 73675 exclusion phecode
960.2 Allergy/adverse effect of penicillin Injuries & Poisonings 1.04 1.02 – 1.07 0.00217 5921 64182 exclusion phecode
961 Poisoning by other anti-infectives Injuries & Poisonings 0.925 0.773 – 1.11 0.395 132 1720 exclusion phecode
961.1 Poisoning/allergy of sulfonamides Injuries & Poisonings 1.02 0.915 – 1.13 0.739 369 3752 exclusion phecode
962 Poisoning by hormones and synthetic substitutes Injuries & Poisonings 0.881 0.731 – 1.06 0.179 124 1441 exclusion phecode
962.3
Hormones and synthetic substitutes causing
Hormones and synthetic substitutes causing adverse effects in therapeutic use
 Injuries & Poisonings 0.912 0.753 – 1.1 0.345 117 1422 exclusion phecode
963 Poisoning by primarily systemic agents Injuries & Poisonings 1.08 0.855 – 1.35 0.533 74 980 exclusion phecode
964
Poisoning by agents primarily affecting blood
Poisoning by agents primarily affecting blood constituents
 Injuries & Poisonings 1.17 0.949 – 1.45 0.141 95 1108 exclusion phecode
964.1 Anticoagulants causing adverse effects Injuries & Poisonings 1.16 0.939 – 1.44 0.166 93 1084 exclusion phecode
965
Poisoning by analgesics, antipyretics, and
Poisoning by analgesics, antipyretics, and antirheumatics
 Injuries & Poisonings 1.07 1.02 – 1.12 0.00311 2102 24800 exclusion phecode
965.1
Opiates and related narcotics causing adverse
Opiates and related narcotics causing adverse effects in therapeutic use
 Injuries & Poisonings 1.05 0.949 – 1.15 0.367 438 4788 exclusion phecode
965.2
Antirheumatics causing adverse effects in
Antirheumatics causing adverse effects in therapeutic use
 Injuries & Poisonings 1.15 0.964 – 1.37 0.122 136 2061 exclusion phecode
965.3
Salicylates causing adverse effects in
Salicylates causing adverse effects in therapeutic use
 Injuries & Poisonings 1.17 0.956 – 1.44 0.127 95 1590 exclusion phecode
966
Poisoning by anticonvulsants and
Poisoning by anticonvulsants and anti-Parkinsonism drugs
 Injuries & Poisonings 1.22 1.04 – 1.42 0.0137 169 2120 exclusion phecode
967
Adverse effects of sedatives or other central
Adverse effects of sedatives or other central nervous system depressants and anesthetics
 Injuries & Poisonings 1.13 0.984 – 1.29 0.0838 224 2363 exclusion phecode
969 Poisoning by psychotropic agents Injuries & Poisonings 1.18 1.08 – 1.29 0.000313 535 8176 exclusion phecode
971
Poisoning by drugs primarily affecting the
Poisoning by drugs primarily affecting the autonomic nervous system
 Injuries & Poisonings 1.36 1.04 – 1.78 0.0263 56 735 exclusion phecode
972
Poisoning by agents primarily affecting the
Poisoning by agents primarily affecting the cardiovascular system
 Injuries & Poisonings 1.59 1.25 – 2.01 0.000129 73 1065 exclusion phecode
972.6 Antihypertensive agents causing adverse effects Injuries & Poisonings 1.95 1.29 – 2.93 0.00143 26 329 exclusion phecode
973
Poisoning by agents primarily affecting the
Poisoning by agents primarily affecting the gastrointestinal system
 Injuries & Poisonings 1.51 1.05 – 2.16 0.0261 33 433 exclusion phecode
974
Poisoning by water, mineral, and uric acid
Poisoning by water, mineral, and uric acid metabolism drugs
 Injuries & Poisonings 1.66 1.09 – 2.54 0.0185 25 372 exclusion phecode
975
Poisoning by agents primarily acting on the
Poisoning by agents primarily acting on the smooth and skeletal muscles and respiratory system
 Injuries & Poisonings 1.25 0.762 – 2.05 0.378 17 251 exclusion phecode
976
Poisoning by agents primarily affecting skin &
Poisoning by agents primarily affecting skin & mucous membrane, ophthalmological, otorhinolaryngological, & dental drugs
 Injuries & Poisonings 1.2 0.755 – 1.89 0.446 19 257 exclusion phecode
977 Personal history of allergy to medicinal agents Injuries & Poisonings 1.05 0.843 – 1.3 0.681 91 978 exclusion phecode
979 Adverse drug events and drug allergies Injuries & Poisonings 1.06 0.917 – 1.22 0.452 214 2937 exclusion phecode
981
Toxic effect of (non-ethyl) alcohol and
Toxic effect of (non-ethyl) alcohol and petroleum and other solvents
 Injuries & Poisonings 1.54 1.17 – 2.04 0.00243 52 839 exclusion phecode
986 Toxic effect of carbon monoxide Injuries & Poisonings 1.67 1.06 – 2.64 0.028 22 252 exclusion phecode
987 Toxic effect of other gases, fumes, or vapors Injuries & Poisonings 0.997 0.644 – 1.54 0.99 22 407 exclusion phecode
988 Toxic effect of noxious substances eaten as food Injuries & Poisonings 1.07 0.767 – 1.49 0.69 38 457 exclusion phecode
989
Toxic effect of other substances, chiefly
Toxic effect of other substances, chiefly nonmedicinal as to source
 Injuries & Poisonings 0.86 0.566 – 1.31 0.479 25 337 exclusion phecode
990 Effects radiation NOS Injuries & Poisonings 0.992 0.929 – 1.06 0.822 974 11919 exclusion phecode
994 Sepsis and SIRS Injuries & Poisonings 0.967 0.907 – 1.03 0.315 1016 11360 exclusion phecode
994.2 Sepsis Injuries & Poisonings 0.967 0.907 – 1.03 0.315 1016 11360 exclusion phecode
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