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Scores Systolic blood pressure, automated Michigan Genomics Initiative Freeze 3 (MGI) PheWAS analysis

Systolic blood pressure, automated — Michigan Genomics Initiative Freeze 3 (MGI) PRS PheWAS

PRS model
PRS ID exprsweb-systolic-blood-pressure-4080-raw-prscs-mgi-freeze3-20211120Legacy PRSCSPRS-CSUK Biobank GWAS

Evaluation cohort: Michigan Genomics Initiative Freeze 3 (MGI).

This page pairs the PheWAS plot with the full sortable table for the all-subject and exclusion scans.

Read the all-subject and exclusion scans separately. The combined view is only a browsing aid, and the selected-phecode panel below is only meaningful when the same phecode exists in both scans.

ExPRS exclusion definition

Exclusion cohort: normal-range subset (0.01-120).

For this ExPRS, the exclusion sensitivity scan keeps only the study's normal-range subset for Systolic blood pressure, automated (0.01-120) before rerunning the PheWAS. This is an exposure-based sensitivity analysis rather than a diagnosis-based exclusion.

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418 rows visible 17 categories
Phecode Description Category OR 95% CI P value Cases Controls Analysis Link
008 Intestinal infection Infectious Diseases 1.03 0.988 – 1.07 0.176 3004 29292 all phecode
008.5 Bacterial enteritis Infectious Diseases 1.08 1.02 – 1.14 0.012 1322 13162 all phecode
008.52 Intestinal infection due to C. difficile Infectious Diseases 1.09 1.02 – 1.16 0.0132 1046 10455 all phecode
008.6 Viral Enteritis Infectious Diseases 1.02 0.943 – 1.1 0.639 770 7676 all phecode
010 Tuberculosis Infectious Diseases 1.03 0.903 – 1.19 0.625 244 2425 all phecode
031 Diseases due to other mycobacteria Infectious Diseases 1.15 0.918 – 1.44 0.225 86 855 all phecode
038 Septicemia Infectious Diseases 1.02 0.983 – 1.07 0.246 2582 24779 all phecode
038.1 Gram negative septicemia Infectious Diseases 0.995 0.911 – 1.09 0.914 568 5629 all phecode
038.2 Gram positive septicemia Infectious Diseases 1.05 0.916 – 1.2 0.492 235 2350 all phecode
038.3 Bacteremia Infectious Diseases 1.03 0.966 – 1.09 0.404 1210 12079 all phecode
041 Bacterial infection NOS Infectious Diseases 1.03 1 – 1.06 0.0521 5750 38799 all phecode
041.1 Staphylococcus infections Infectious Diseases 1.06 1 – 1.11 0.0338 1707 16977 all phecode
041.11 Methicillin sensitive Staphylococcus aureus Infectious Diseases 1.04 0.97 – 1.11 0.28 920 9192 all phecode
041.12 Methicillin resistant Staphylococcus aureus Infectious Diseases 1.09 1.01 – 1.18 0.0236 783 7812 all phecode
041.2 Streptococcus infection Infectious Diseases 1.05 0.993 – 1.1 0.092 1632 16287 all phecode
041.21 Rheumatic fever / chorea Infectious Diseases 1.04 0.91 – 1.18 0.593 257 2554 all phecode
041.4 E. coli Infectious Diseases 1.04 0.974 – 1.1 0.267 1175 11680 all phecode
041.8 H. pylori Infectious Diseases 0.972 0.852 – 1.11 0.666 257 2521 all phecode
041.9 Infection with drug-resistant microorganisms Infectious Diseases 1.11 0.993 – 1.23 0.0674 387 3864 all phecode
053 Herpes zoster Infectious Diseases 0.946 0.896 – 0.998 0.0418 1560 15184 all phecode
053.1 Herpes zoster with nervous system complications Infectious Diseases 1.1 0.948 – 1.27 0.217 220 2169 all phecode
054 Herpes simplex Infectious Diseases 0.961 0.912 – 1.01 0.144 1593 15600 all phecode
070 Viral hepatitis Infectious Diseases 0.991 0.921 – 1.07 0.798 829 8280 all phecode
070.1 Viral hepatitis A Infectious Diseases 1.07 0.852 – 1.34 0.57 87 860 all phecode
070.2 Viral hepatitis B Infectious Diseases 0.991 0.86 – 1.14 0.902 215 2138 all phecode
070.3 Viral hepatitis C Infectious Diseases 0.975 0.889 – 1.07 0.584 528 5280 all phecode
070.4 Chronic hepatitis Infectious Diseases 1.02 0.874 – 1.19 0.82 197 1964 all phecode
070.9 Hepatitis NOS Infectious Diseases 0.955 0.898 – 1.02 0.145 1145 11381 all phecode
071 Human immunodeficiency virus [HIV] disease Infectious Diseases 1.06 0.887 – 1.27 0.505 145 1450 all phecode
071.1 HIV infection, symptomatic Infectious Diseases 1.02 0.838 – 1.25 0.817 117 1163 all phecode
078 Viral warts & HPV Infectious Diseases 0.919 0.886 – 0.953 5.43e-06 3434 29624 all phecode
079 Viral infection Infectious Diseases 0.99 0.964 – 1.02 0.477 6664 35342 all phecode
079.1 Varicella infection Infectious Diseases 0.972 0.939 – 1.01 0.111 3793 31251 all phecode
079.2 Infectious mononucleosis Infectious Diseases 0.979 0.865 – 1.11 0.74 283 2723 all phecode
079.9 Viremia, NOS Infectious Diseases 1.04 0.968 – 1.12 0.275 838 8253 all phecode
080 Postoperative infection Infectious Diseases 1.03 0.984 – 1.07 0.23 2619 26065 all phecode
081
Infection/inflammation of internal prosthetic
Infection/inflammation of internal prosthetic device; implant; and graft
 Infectious Diseases 1.03 0.979 – 1.09 0.245 1589 15884 all phecode
090
Sexually transmitted infections (not HIV or
Sexually transmitted infections (not HIV or hepatitis)
 Infectious Diseases 1.02 0.953 – 1.09 0.564 965 9630 all phecode
110 Dermatophytosis / Dermatomycosis Infectious Diseases 0.959 0.924 – 0.994 0.0221 3544 30054 all phecode
110.1 Dermatophytosis Infectious Diseases 0.959 0.923 – 0.997 0.0323 3241 27244 all phecode
110.11 Dermatophytosis of nail Infectious Diseases 0.978 0.932 – 1.03 0.372 2044 16765 all phecode
110.12 Althete's foot Infectious Diseases 0.953 0.887 – 1.02 0.191 899 8043 all phecode
110.13 Dermatophytosis of the body Infectious Diseases 0.95 0.881 – 1.02 0.185 790 7827 all phecode
110.2 Dermatomycoses Infectious Diseases 0.937 0.844 – 1.04 0.217 398 3971 all phecode
112 Candidiasis Infectious Diseases 1.03 0.993 – 1.07 0.115 3685 30495 all phecode
112.3 Candidiasis of skin and nails Infectious Diseases 1 0.925 – 1.09 0.949 682 6732 all phecode
117 Mycoses Infectious Diseases 1.03 0.949 – 1.12 0.461 608 6069 all phecode
117.1 Histoplasmosis Infectious Diseases 0.915 0.727 – 1.15 0.45 81 801 all phecode
117.4 Aspergillosis Infectious Diseases 1.06 0.889 – 1.26 0.519 140 1387 all phecode
130 Spirochetal infection Infectious Diseases 0.845 0.719 – 0.993 0.0411 168 1677 all phecode
130.1 Lyme disease Infectious Diseases 0.761 0.625 – 0.927 0.00676 116 1160 all phecode
131 Protozoan infection Infectious Diseases 0.976 0.743 – 1.28 0.862 61 610 all phecode
132 Infestation (lice, mites) Infectious Diseases 0.987 0.845 – 1.15 0.864 195 1948 all phecode
134 Helminthiases Infectious Diseases 1.11 0.889 – 1.4 0.348 83 812 all phecode
134.1 Intestinal helminthiases Infectious Diseases 1.14 0.849 – 1.53 0.385 53 513 all phecode
136 Other infectious and parasitic diseases Infectious Diseases 0.981 0.946 – 1.02 0.308 3279 32486 all phecode
145 Cancer of mouth Neoplasms 1.02 0.967 – 1.08 0.454 1481 14725 all phecode
145.1 Cancer of lip Neoplasms 0.999 0.779 – 1.28 0.996 76 750 all phecode
145.2 Cancer of tongue Neoplasms 1.04 0.954 – 1.13 0.395 645 6430 all phecode
145.3 Cancer of major salivary glands Neoplasms 0.945 0.847 – 1.05 0.314 361 3597 all phecode
145.4 Cancer of the gums Neoplasms 1.11 0.946 – 1.31 0.195 166 1632 all phecode
145.5 Cancer of the mouth floor Neoplasms 1.07 0.928 – 1.24 0.342 206 2048 all phecode
149 Cancer of larynx, pharynx, nasal cavities Neoplasms 1.01 0.956 – 1.07 0.648 1290 12873 all phecode
149.1 Cancer of oropharynx Neoplasms 1.12 1.01 – 1.26 0.0399 350 3499 all phecode
149.2 Cancer of nasopharynx Neoplasms 1.02 0.825 – 1.25 0.882 100 1000 all phecode
149.3 Cancer of hypopharynx Neoplasms 0.858 0.687 – 1.07 0.174 82 819 all phecode
149.4 Cancer of larynx Neoplasms 1.05 0.947 – 1.17 0.35 386 3857 all phecode
149.5
Hx of malignant neoplasm of oral cavity and
Hx of malignant neoplasm of oral cavity and pharynx
 Neoplasms 0.921 0.843 – 1.01 0.0715 552 5505 all phecode
149.9 Cancer of of nasal cavities Neoplasms 1.05 0.922 – 1.21 0.438 240 2398 all phecode
150 Cancer of esophagus Neoplasms 0.986 0.892 – 1.09 0.786 433 4315 all phecode
151 Cancer of stomach Neoplasms 1.02 0.93 – 1.12 0.652 498 4962 all phecode
153 Colorectal cancer Neoplasms 1.02 0.962 – 1.07 0.562 1458 14383 all phecode
153.2 Colon cancer Neoplasms 1.02 0.958 – 1.08 0.553 1160 11472 all phecode
153.3
Malignant neoplasm of rectum, rectosigmoid
Malignant neoplasm of rectum, rectosigmoid junction, and anus
 Neoplasms 0.997 0.926 – 1.07 0.936 815 8093 all phecode
155 Cancer of liver and intrahepatic bile duct Neoplasms 1.03 0.936 – 1.13 0.571 511 5097 all phecode
155.1 Malignant neoplasm of liver, primary Neoplasms 1.06 0.948 – 1.19 0.305 344 3433 all phecode
157 Pancreatic cancer Neoplasms 0.963 0.876 – 1.06 0.43 503 5005 all phecode
158
Neoplasm of unspecified nature of digestive
Neoplasm of unspecified nature of digestive system
 Neoplasms 1.03 0.98 – 1.09 0.229 1623 15759 all phecode
159
Malignant neoplasm of other and ill-defined
Malignant neoplasm of other and ill-defined sites within the digestive organs and peritoneum
 Neoplasms 0.997 0.949 – 1.05 0.896 1818 17869 all phecode
159.2
Malignant neoplasm of small intestine
Malignant neoplasm of small intestine, including duodenum
 Neoplasms 1.03 0.896 – 1.18 0.685 221 2206 all phecode
159.3
Malignant neoplasm of gallbladder and
Malignant neoplasm of gallbladder and extrahepatic bile ducts
 Neoplasms 1.01 0.854 – 1.2 0.9 158 1578 all phecode
159.4
Malignant neoplasm of retroperitoneum and
Malignant neoplasm of retroperitoneum and peritoneum
 Neoplasms 1.03 0.915 – 1.17 0.587 293 2920 all phecode
164 Cancer of intrathoracic organs Neoplasms 1.04 0.864 – 1.25 0.697 133 1324 all phecode
165 Cancer within the respiratory system Neoplasms 1.02 0.959 – 1.08 0.599 1336 13340 all phecode
165.1 Cancer of bronchus; lung Neoplasms 1.03 0.964 – 1.1 0.391 1057 10552 all phecode
170 Cancer of bone and connective tissue Neoplasms 1 0.955 – 1.06 0.877 1792 17850 all phecode
170.1 Bone cancer Neoplasms 1.04 0.96 – 1.12 0.364 773 7690 all phecode
170.2 Cancer of connective tissue Neoplasms 0.992 0.935 – 1.05 0.782 1266 12632 all phecode
172 Skin cancer Neoplasms 1.01 0.986 – 1.04 0.403 8608 33186 all phecode
172.1 Melanomas of skin, dx or hx Neoplasms 1.01 0.975 – 1.04 0.721 5330 30106 all phecode
172.11 Melanomas of skin Neoplasms 1.01 0.974 – 1.05 0.551 3100 25064 all phecode
172.2 Other non-epithelial cancer of skin Neoplasms 1.01 0.978 – 1.03 0.712 7095 30462 all phecode
172.21 Basal cell carcinoma Neoplasms 0.993 0.958 – 1.03 0.709 3690 23868 all phecode
172.22 Squamous cell carcinoma Neoplasms 1.03 0.987 – 1.08 0.17 2414 17683 all phecode
172.3 Carcinoma in situ of skin Neoplasms 1.02 0.969 – 1.08 0.392 1482 12326 all phecode
173 Neoplasm of uncertain behavior of skin Neoplasms 0.991 0.945 – 1.04 0.697 1997 18755 all phecode
174 Breast cancer Neoplasms 0.953 0.916 – 0.991 0.0168 3186 15514 all phecode
174.1 Breast cancer [female] Neoplasms 0.953 0.915 – 0.992 0.0194 3036 14701 all phecode
174.11 Malignant neoplasm of female breast Neoplasms 0.951 0.913 – 0.991 0.0167 2991 14639 all phecode
174.3 Neoplasm of uncertain behavior of breast Neoplasms 0.985 0.858 – 1.13 0.829 233 2307 all phecode
175 Acquired absence of breast Neoplasms 0.966 0.901 – 1.04 0.337 919 8920 all phecode
180 Cervical cancer and dysplasia Neoplasms 0.972 0.919 – 1.03 0.319 1431 12185 all phecode
180.1 Cervical cancer Neoplasms 0.954 0.87 – 1.05 0.325 500 4982 all phecode
180.3
Cervical intraepithelial neoplasia [CIN]
Cervical intraepithelial neoplasia [CIN] [Cervical dysplasia]
 Neoplasms 0.954 0.894 – 1.02 0.154 1048 9323 all phecode
182 Malignant neoplasm of uterus Neoplasms 0.965 0.895 – 1.04 0.355 765 7613 all phecode
184 Cancer of other female genital organs Neoplasms 1 0.945 – 1.07 0.901 1191 11592 all phecode
184.1
Malignant neoplasm of ovary and other uterine
Malignant neoplasm of ovary and other uterine adnexa
 Neoplasms 0.964 0.884 – 1.05 0.41 573 5719 all phecode
184.11 Malignant neoplasm of ovary Neoplasms 0.977 0.884 – 1.08 0.644 432 4309 all phecode
184.2
Cancer of other female genital organs
Cancer of other female genital organs (excluding uterus and ovary)
 Neoplasms 1.11 1.02 – 1.21 0.0212 608 6057 all phecode
185 Cancer of prostate Neoplasms 0.971 0.93 – 1.01 0.192 2901 10342 all phecode
187 Cancer of other male genital organs Neoplasms 1.05 0.938 – 1.18 0.39 339 3384 all phecode
187.1
Malignant neoplasm of unspecified male genital
Malignant neoplasm of unspecified male genital organ
 Neoplasms 0.983 0.811 – 1.19 0.858 115 1141 all phecode
187.2 Malignant neoplasm of testis Neoplasms 1.05 0.896 – 1.23 0.543 183 1830 all phecode
187.8
Neoplasm of uncertain behavior of male genital
Neoplasm of uncertain behavior of male genital organs
 Neoplasms 1.17 0.884 – 1.54 0.279 57 562 all phecode
189
Cancer of urinary organs (incl. kidney and
Cancer of urinary organs (incl. kidney and bladder)
 Neoplasms 1.04 0.999 – 1.08 0.0582 2923 23541 all phecode
189.1 Cancer of kidney and renal pelvis Neoplasms 1.06 1.01 – 1.12 0.0295 1450 14437 all phecode
189.11 Malignant neoplasm of kidney, except pelvis Neoplasms 1.05 0.994 – 1.12 0.0801 1267 12655 all phecode
189.12 Malignant neoplasm of renal pelvis Neoplasms 1.03 0.896 – 1.18 0.711 237 2347 all phecode
189.2 Cancer of bladder Neoplasms 1 0.955 – 1.06 0.865 1783 15224 all phecode
189.21 Malignant neoplasm of bladder Neoplasms 1.01 0.954 – 1.06 0.847 1657 14178 all phecode
189.4 Malignant neoplasm of other urinary organs Neoplasms 1.01 0.93 – 1.09 0.848 678 6586 all phecode
190 Cancer of eye Neoplasms 1.2 1 – 1.43 0.0452 138 1374 all phecode
191
Manlignant and unknown neoplasms of brain and
Manlignant and unknown neoplasms of brain and nervous system
 Neoplasms 0.998 0.936 – 1.07 0.959 1078 10771 all phecode
191.1 Cancer of brain and nervous system Neoplasms 1.02 0.944 – 1.11 0.585 706 7052 all phecode
191.11 Cancer of brain Neoplasms 1.03 0.947 – 1.12 0.475 600 5996 all phecode
193 Thyroid cancer Neoplasms 0.977 0.912 – 1.05 0.509 945 9393 all phecode
194 Cancer of other endocrine glands Neoplasms 1.02 0.935 – 1.11 0.653 579 5759 all phecode
195 Cancer, suspected or other Neoplasms 1.02 1 – 1.04 0.0515 16962 26401 all phecode
195.1 Malignant neoplasm, other Neoplasms 1.02 0.999 – 1.04 0.0565 16670 26384 all phecode
195.3 Malignant neoplasm of head, face, and neck Neoplasms 1.04 0.975 – 1.11 0.232 1103 9766 all phecode
196 Radiotherapy Neoplasms 1 0.958 – 1.05 0.947 2427 17006 all phecode
197 Chemotherapy Neoplasms 1.02 0.986 – 1.05 0.274 4952 23797 all phecode
198 Secondary malignant neoplasm Neoplasms 1.04 1.01 – 1.08 0.00668 5801 23481 all phecode
198.1 Secondary malignancy of lymph nodes Neoplasms 1.03 0.992 – 1.07 0.121 3677 21489 all phecode
198.2 Secondary malignancy of respiratory organs Neoplasms 1.06 0.992 – 1.13 0.0857 1072 10334 all phecode
198.3
Secondary malignant neoplasm of digestive
Secondary malignant neoplasm of digestive systems
 Neoplasms 1.05 0.975 – 1.12 0.208 866 8538 all phecode
198.4 Secondary malignant neoplasm of liver Neoplasms 1.06 0.98 – 1.14 0.147 767 7558 all phecode
198.5 Secondary malignancy of brain/spine Neoplasms 0.984 0.905 – 1.07 0.711 640 6338 all phecode
198.6 Secondary malignancy of bone Neoplasms 1.07 0.991 – 1.14 0.0857 866 8307 all phecode
198.7 Secondary malignant neoplasm of skin Neoplasms 1.05 0.931 – 1.17 0.448 336 3253 all phecode
199 Neoplasm of uncertain behavior Neoplasms 1.02 0.994 – 1.06 0.117 5693 25767 all phecode
199.4 Neurofibromatosis Neoplasms 1.03 0.83 – 1.29 0.765 88 880 all phecode
200 Myeloproliferative disease Neoplasms 1.03 0.967 – 1.1 0.352 1113 11098 all phecode
200.1 Polycythemia vera Neoplasms 0.978 0.854 – 1.12 0.752 231 2310 all phecode
201 Hodgkin's disease Neoplasms 0.972 0.831 – 1.14 0.725 172 1705 all phecode
202 Cancer of other lymphoid, histiocytic tissue Neoplasms 1.04 0.985 – 1.1 0.157 1559 15571 all phecode
202.2 Non-Hodgkins lymphoma Neoplasms 1.03 0.975 – 1.1 0.263 1329 13268 all phecode
202.21 Nodular lymphoma Neoplasms 1.02 0.937 – 1.1 0.712 693 6923 all phecode
202.22 Reticulosarcoma Neoplasms 1.07 0.91 – 1.26 0.413 170 1693 all phecode
202.24 Large cell lymphoma Neoplasms 1 0.843 – 1.19 0.999 160 1586 all phecode
204 Leukemia Neoplasms 1.11 1.02 – 1.2 0.0142 689 6876 all phecode
204.1 Lymphoid leukemia Neoplasms 1.08 0.945 – 1.24 0.256 236 2354 all phecode
204.11 Lymphoid leukemia, acute Neoplasms 1.07 0.839 – 1.37 0.57 74 734 all phecode
204.12 Lymphoid leukemia, chronic Neoplasms 1.11 0.947 – 1.29 0.202 173 1724 all phecode
204.2 Myeloid leukemia Neoplasms 1.08 0.946 – 1.23 0.259 265 2633 all phecode
204.21 Myeloid leukemia, acute Neoplasms 1.13 0.957 – 1.34 0.147 153 1516 all phecode
204.22 Myeloid leukemia, chronic Neoplasms 1.03 0.798 – 1.34 0.802 61 610 all phecode
204.4 Multiple myeloma Neoplasms 1.16 1.01 – 1.35 0.0402 217 2162 all phecode
208 Benign neoplasm of colon Neoplasms 0.952 0.93 – 0.974 2.45e-05 10303 34953 all phecode
209 Neuroendocrine tumors Neoplasms 1.04 0.912 – 1.18 0.579 258 2580 all phecode
210 Benign neoplasm of lip, oral cavity, and pharynx Neoplasms 1.03 0.983 – 1.08 0.202 1891 18839 all phecode
211
Benign neoplasm of other parts of digestive
Benign neoplasm of other parts of digestive system
 Neoplasms 1.01 0.986 – 1.04 0.354 7329 36606 all phecode
212
Benign neoplasm of respiratory and
Benign neoplasm of respiratory and intrathoracic organs
 Neoplasms 1 0.953 – 1.05 0.984 1843 18412 all phecode
213 Benign neoplasm of bone and articular cartilage Neoplasms 0.989 0.94 – 1.04 0.685 1677 15527 all phecode
214 Lipoma Neoplasms 0.955 0.903 – 1.01 0.107 1437 14132 all phecode
214.1 Lipoma of skin and subcutaneous tissue Neoplasms 0.984 0.916 – 1.06 0.648 883 8710 all phecode
215
Other benign neoplasm of connective and other
Other benign neoplasm of connective and other soft tissue
 Neoplasms 1 0.973 – 1.04 0.776 4528 39509 all phecode
216 Benign neoplasm of skin Neoplasms 0.978 0.957 – 1 0.0482 11528 34919 all phecode
216.1 Screening for malignant neoplasms of the skin Neoplasms 0.994 0.849 – 1.16 0.941 174 1701 all phecode
217 Vascular hamartomas and non-neoplastic nevi Neoplasms 0.918 0.873 – 0.965 0.000772 1786 17184 all phecode
217.1 Nevus, non-neoplastic Neoplasms 0.913 0.867 – 0.961 0.00056 1679 16116 all phecode
218 Benign neoplasm of uterus Neoplasms 0.997 0.963 – 1.03 0.857 4301 16661 all phecode
218.1 Uterine leiomyoma Neoplasms 0.984 0.936 – 1.03 0.527 1835 15733 all phecode
218.2 Other benign neoplasm of uterus Neoplasms 0.999 0.962 – 1.04 0.964 3403 16447 all phecode
220 Benign neoplasm of ovary Neoplasms 1.04 0.967 – 1.11 0.31 893 8783 all phecode
221 Benign neoplasm of other female genital organs Neoplasms 1.02 0.975 – 1.07 0.357 2042 14248 all phecode
222 Benign neoplasm of male genital organs Neoplasms 0.92 0.864 – 0.979 0.00912 1133 10663 all phecode
223
Benign neoplasm of kidney and other urinary
Benign neoplasm of kidney and other urinary organs
 Neoplasms 1.01 0.96 – 1.06 0.687 1801 12657 all phecode
224 Benign neoplasm of eye Neoplasms 1.06 0.978 – 1.15 0.16 691 6752 all phecode
224.1 Benign neoplasm of eye, uveal Neoplasms 1.05 0.967 – 1.15 0.229 595 5773 all phecode
225
Benign neoplasm of brain and other parts of
Benign neoplasm of brain and other parts of nervous system
 Neoplasms 1.07 1.01 – 1.14 0.0248 1209 12074 all phecode
225.1
Benign neoplasm of brain, cranial nerves
Benign neoplasm of brain, cranial nerves, meninges
 Neoplasms 1.09 1.01 – 1.16 0.0173 947 9454 all phecode
225.2 Benign neoplasm of spinal cord, meninges Neoplasms 1.05 0.932 – 1.19 0.406 289 2890 all phecode
226 Benign neoplasm of thyroid glands Neoplasms 1.02 0.964 – 1.08 0.472 1329 13264 all phecode
227
Benign neoplasm of other endocrine glands and
Benign neoplasm of other endocrine glands and related structures
 Neoplasms 1.09 1.03 – 1.15 0.00118 1690 16896 all phecode
227.1 Benign neoplasm of adrenal gland Neoplasms 1.12 1.01 – 1.23 0.0285 467 4644 all phecode
227.2 Benign neoplasm of parathyroid gland Neoplasms 1.1 1.02 – 1.19 0.0112 795 7941 all phecode
227.3
Benign neoplasm of pituitary gland and
Benign neoplasm of pituitary gland and craniopharyngeal duct (pouch)
 Neoplasms 1.06 0.956 – 1.17 0.284 435 4350 all phecode
228 Hemangioma and lymphangioma, any site Neoplasms 0.943 0.901 – 0.987 0.0114 2149 20946 all phecode
228.1 Hemangioma of skin and subcutaneous tissue Neoplasms 0.948 0.895 – 1 0.0661 1356 13336 all phecode
229 Benign neoplasm of unspecified sites Neoplasms 1.01 0.981 – 1.03 0.64 7767 36615 all phecode
229.1 Benign neoplasm of lymph nodes Neoplasms 0.998 0.97 – 1.03 0.895 5743 34218 all phecode
240 Simple and unspecified goiter Endocrine/metabolic 1.02 0.953 – 1.09 0.589 1031 9761 all phecode
241 Nontoxic nodular goiter Endocrine/metabolic 1.01 0.97 – 1.05 0.636 2910 22227 all phecode
241.1 Nontoxic uninodular goiter Endocrine/metabolic 1 0.956 – 1.05 0.997 2265 19902 all phecode
241.2 Nontoxic multinodular goiter Endocrine/metabolic 1.06 1 – 1.13 0.0372 1304 12479 all phecode
242 Thyrotoxicosis with or without goiter Endocrine/metabolic 1.04 0.981 – 1.1 0.196 1400 13425 all phecode
242.1 Graves' disease Endocrine/metabolic 1.12 1.02 – 1.23 0.0164 515 5068 all phecode
242.2 Toxic multinodular goiter Endocrine/metabolic 1.1 0.911 – 1.33 0.319 124 1224 all phecode
242.3 Exophthalmos Endocrine/metabolic 1.09 0.964 – 1.23 0.172 292 2898 all phecode
242.31 Thyrotoxic exophthalmos Endocrine/metabolic 1.12 0.946 – 1.33 0.187 144 1432 all phecode
244 Hypothyroidism Endocrine/metabolic 1.03 1 – 1.05 0.046 8099 32717 all phecode
244.1 Secondary hypothyroidism Endocrine/metabolic 1.05 1 – 1.11 0.0416 1762 17230 all phecode
244.2 Acquired hypothyroidism Endocrine/metabolic 1.02 0.959 – 1.08 0.567 1261 11982 all phecode
244.4 Hypothyroidism NOS Endocrine/metabolic 1.02 0.997 – 1.05 0.0851 7542 32208 all phecode
245 Thyroiditis Endocrine/metabolic 0.973 0.904 – 1.05 0.467 832 7882 all phecode
245.2 Chronic thyroiditis Endocrine/metabolic 0.986 0.909 – 1.07 0.735 686 6517 all phecode
245.21 Chronic lymphocytic thyroiditis Endocrine/metabolic 0.993 0.915 – 1.08 0.866 679 6449 all phecode
246 Other disorders of thyroid Endocrine/metabolic 1.04 1.01 – 1.07 0.0145 6129 30240 all phecode
246.2 Thyroid cyst Endocrine/metabolic 1.07 0.868 – 1.32 0.519 101 960 all phecode
246.7 Abnormal results of function study of thyroid Endocrine/metabolic 1 0.934 – 1.08 0.92 886 8696 all phecode
249 Secondary diabetes mellitus Endocrine/metabolic 1.22 1.13 – 1.31 8.13e-08 1150 8340 all phecode
250 Diabetes mellitus Endocrine/metabolic 1.11 1.09 – 1.13 2.84e-20 13947 31815 all phecode
250.1 Type 1 diabetes Endocrine/metabolic 1.16 1.09 – 1.23 9.57e-07 2364 11758 all phecode
250.11 Type 1 diabetes with ketoacidosis Endocrine/metabolic 1.21 1.02 – 1.44 0.0325 262 960 all phecode
250.12 Type 1 diabetes with renal manifestations Endocrine/metabolic 1.2 1.07 – 1.35 0.00259 551 2686 all phecode
250.13 Type 1 diabetes with ophthalmic manifestations Endocrine/metabolic 1.15 1.03 – 1.28 0.0143 784 3018 all phecode
250.14 Type 1 diabetes with neurological manifestations Endocrine/metabolic 1.22 1.09 – 1.37 0.000853 638 2675 all phecode
250.15
Diabetes type 1 with peripheral circulatory
Diabetes type 1 with peripheral circulatory disorders
 Endocrine/metabolic 1.22 0.998 – 1.48 0.0518 155 850 all phecode
250.2 Type 2 diabetes Endocrine/metabolic 1.16 1.13 – 1.19 3.64e-28 9843 29688 all phecode
250.21 Type 2 diabetes with ketoacidosis Endocrine/metabolic 1.27 1.09 – 1.48 0.00232 282 1327 all phecode
250.22 Type 2 diabetes with renal manifestations Endocrine/metabolic 1.27 1.2 – 1.34 2.92e-17 1941 13510 all phecode
250.23 Type 2 diabetes with ophthalmic manifestations Endocrine/metabolic 1.14 1.07 – 1.22 5.39e-05 1643 9668 all phecode
250.24 Type 2 diabetes with neurological manifestations Endocrine/metabolic 1.21 1.15 – 1.27 2e-13 2557 16502 all phecode
250.25
Diabetes type 2 with peripheral circulatory
Diabetes type 2 with peripheral circulatory disorders
 Endocrine/metabolic 1.38 1.27 – 1.5 2.95e-14 860 6143 all phecode
250.3 Insulin pump user Endocrine/metabolic 1.2 1.15 – 1.25 8.97e-16 3496 20809 all phecode
250.4 Abnormal glucose Endocrine/metabolic 1.08 1.05 – 1.11 2.09e-08 8385 30645 all phecode
250.41 Impaired fasting glucose Endocrine/metabolic 1.06 1.01 – 1.12 0.0284 1870 15861 all phecode
250.42 Other abnormal glucose Endocrine/metabolic 1.09 1.05 – 1.12 1.66e-08 7553 30071 all phecode
250.5 Glycosuria or Acetonuria Endocrine/metabolic 0.82 0.677 – 0.993 0.0421 136 1067 all phecode
250.6 Polyneuropathy in diabetes Endocrine/metabolic 1.22 1.15 – 1.29 4.5e-12 2132 13390 all phecode
250.7 Diabetic retinopathy Endocrine/metabolic 1.13 1.06 – 1.19 3.83e-05 1691 10517 all phecode
251 Other disorders of pancreatic internal secretion Endocrine/metabolic 1.09 1.01 – 1.16 0.0171 991 8469 all phecode
251.1 Hypoglycemia Endocrine/metabolic 1.1 1.02 – 1.18 0.00843 1207 8570 all phecode
252 Disorders of parathyroid gland Endocrine/metabolic 1.1 1.05 – 1.15 1.49e-05 2282 22119 all phecode
252.1 Hyperparathyroidism Endocrine/metabolic 1.1 1.05 – 1.15 9.63e-05 2088 20335 all phecode
252.2 Hypoparathyroidism Endocrine/metabolic 1.06 0.966 – 1.16 0.218 508 5073 all phecode
253
Disorders of the pituitary gland and its
Disorders of the pituitary gland and its hypothalamic control
 Endocrine/metabolic 1.07 0.996 – 1.15 0.0651 859 8544 all phecode
253.1 Pituitary hyperfunction Endocrine/metabolic 1.14 1 – 1.3 0.0506 263 2621 all phecode
253.11 Acromegaly and gigantism Endocrine/metabolic 1.18 0.948 – 1.48 0.136 83 826 all phecode
253.2 Pituitary hypofunction Endocrine/metabolic 1.12 0.97 – 1.29 0.125 226 2250 all phecode
253.3 Diabetes insipidus Endocrine/metabolic 1.61 1.28 – 2.02 4.56e-05 86 860 all phecode
253.4 Anterior pituitary disorders Endocrine/metabolic 1.11 0.908 – 1.35 0.318 121 1209 all phecode
253.7 Other disorders of neurohypophysis Endocrine/metabolic 0.909 0.745 – 1.11 0.347 108 1080 all phecode
255 Disorders of adrenal glands Endocrine/metabolic 1.05 0.994 – 1.11 0.0794 1506 14869 all phecode
255.1 Adrenal hyperfunction Endocrine/metabolic 1.09 0.98 – 1.22 0.109 373 3730 all phecode
255.11 Cushing's syndrome Endocrine/metabolic 1 0.859 – 1.17 0.99 183 1830 all phecode
255.12 Hyperaldosteronism Endocrine/metabolic 1.22 1.02 – 1.46 0.0304 135 1350 all phecode
255.2 Adrenal hypofunction Endocrine/metabolic 1.09 1.01 – 1.19 0.0374 626 6239 all phecode
255.21 Glucocorticoid deficiency Endocrine/metabolic 1.1 1 – 1.2 0.0404 596 5941 all phecode
256 Ovarian dysfunction Endocrine/metabolic 1.06 1 – 1.13 0.0493 1146 10513 all phecode
256.4 Polycystic ovaries Endocrine/metabolic 1.06 0.978 – 1.14 0.158 742 7128 all phecode
257 Testicular dysfunction Endocrine/metabolic 0.984 0.92 – 1.05 0.642 1015 9238 all phecode
257.1 Testicular hypofunction Endocrine/metabolic 0.986 0.921 – 1.06 0.694 983 8933 all phecode
258 Iatrogenic endocrine disorders Endocrine/metabolic 1.22 0.97 – 1.54 0.0889 91 910 all phecode
258.1 Postablative ovarian failure Endocrine/metabolic 1 0.828 – 1.22 0.962 109 1090 all phecode
259 Other endocrine disorders Endocrine/metabolic 1.05 0.983 – 1.12 0.149 1038 10259 all phecode
260 Protein-calorie malnutrition Endocrine/metabolic 1.06 1.01 – 1.1 0.00766 2880 26812 all phecode
260.1 Cachexia Endocrine/metabolic 1.04 0.917 – 1.17 0.57 292 2911 all phecode
260.2 severe protein-calorie malnutrition Endocrine/metabolic 1.04 0.988 – 1.09 0.134 1691 16847 all phecode
260.22 Nutritional marasmus Endocrine/metabolic 1.05 0.963 – 1.14 0.276 614 6140 all phecode
260.3 Adult failure to thrive Endocrine/metabolic 1.09 1 – 1.18 0.0513 629 6236 all phecode
260.6 Anorexia Endocrine/metabolic 0.993 0.925 – 1.07 0.846 868 8591 all phecode
260.7 Polyphagia Endocrine/metabolic 0.983 0.758 – 1.28 0.9 65 643 all phecode
261 Vitamin deficiency Endocrine/metabolic 1.03 1 – 1.06 0.0256 7718 35203 all phecode
261.1 Vitamin A deficiency Endocrine/metabolic 0.971 0.754 – 1.25 0.821 69 690 all phecode
261.2 Vitamin B-complex deficiencies Endocrine/metabolic 0.979 0.911 – 1.05 0.565 857 8405 all phecode
261.4 Vitamin D deficiency Endocrine/metabolic 1.03 1 – 1.06 0.0286 7255 35225 all phecode
261.41 Rickets or osteomalacia Endocrine/metabolic 1.13 0.844 – 1.5 0.418 52 511 all phecode
262 Mineral deficiency NEC Endocrine/metabolic 1.03 0.964 – 1.09 0.426 1182 11676 all phecode
263 Other nutritional deficiency Endocrine/metabolic 1.04 0.984 – 1.09 0.176 1651 15788 all phecode
264 Lack of normal physiological development Endocrine/metabolic 1.16 1.01 – 1.33 0.0312 239 2301 all phecode
264.2 Failure to thrive (childhood) Endocrine/metabolic 1.14 0.937 – 1.37 0.194 122 1220 all phecode
264.9
Lack of normal physiological development
Lack of normal physiological development, unspecified
 Endocrine/metabolic 1.05 0.829 – 1.32 0.696 81 772 all phecode
269 Proteinuria Endocrine/metabolic 1.16 1.1 – 1.22 2.34e-08 1694 13981 all phecode
270
Disorders of protein plasma/amino-acid
Disorders of protein plasma/amino-acid transport and metabolism
 Endocrine/metabolic 1.07 0.999 – 1.15 0.0531 967 9575 all phecode
270.1 Disturbances of amino-acid transport Endocrine/metabolic 1.08 0.924 – 1.27 0.328 170 1697 all phecode
270.11
Disturbances of sulphur-bearing amino-acid
Disturbances of sulphur-bearing amino-acid metabolism
 Endocrine/metabolic 1.04 0.869 – 1.24 0.67 134 1334 all phecode
270.2 Disorders of amino-acid metabolism Endocrine/metabolic 1.2 0.963 – 1.49 0.105 96 954 all phecode
270.3 Disorders of plasma protein metabolism Endocrine/metabolic 1.04 0.964 – 1.13 0.299 737 7303 all phecode
270.32 Paraproteinemia Endocrine/metabolic 1.08 0.972 – 1.21 0.15 384 3781 all phecode
270.33 Amyloidosis Endocrine/metabolic 0.879 0.689 – 1.12 0.3 71 695 all phecode
270.34 Alpha-1-antitrypsin deficiency Endocrine/metabolic 0.91 0.702 – 1.18 0.479 69 690 all phecode
270.38
Other specified disorders of plasma protein
Other specified disorders of plasma protein metabolism
 Endocrine/metabolic 1.02 0.902 – 1.16 0.739 299 2984 all phecode
271
Disorders of carbohydrate transport and
Disorders of carbohydrate transport and metabolism
 Endocrine/metabolic 1.01 0.971 – 1.05 0.611 2907 28132 all phecode
271.3
Intestinal disaccharidase deficiencies and
Intestinal disaccharidase deficiencies and disaccharide malabsorption
 Endocrine/metabolic 1.01 0.974 – 1.05 0.514 2827 27425 all phecode
271.9
Other disorders of carbohydrate transport and
Other disorders of carbohydrate transport and metabolism
 Endocrine/metabolic 0.839 0.683 – 1.03 0.0933 102 1007 all phecode
272 Disorders of lipoid metabolism Endocrine/metabolic 1.09 1.07 – 1.11 8.72e-16 18881 26670 all phecode
272.1 Hyperlipidemia Endocrine/metabolic 1.09 1.07 – 1.11 8.04e-16 18843 26654 all phecode
272.11 Hypercholesterolemia Endocrine/metabolic 1.09 1.06 – 1.12 1.23e-07 5928 21600 all phecode
272.12 Hyperglyceridemia Endocrine/metabolic 1.09 1.03 – 1.16 0.00399 1360 11837 all phecode
272.13 Mixed hyperlipidemia Endocrine/metabolic 1.12 1.08 – 1.17 1.03e-08 3538 18449 all phecode
272.9 Unspecified disorder of lipoid metabolism Endocrine/metabolic 1.05 0.927 – 1.18 0.467 313 3011 all phecode
274 Gout and other crystal arthropathies Endocrine/metabolic 1.11 1.07 – 1.16 8.56e-07 2524 22729 all phecode
274.1 Gout Endocrine/metabolic 1.12 1.07 – 1.17 2e-07 2409 21991 all phecode
274.11 Gouty arthropathy Endocrine/metabolic 1.13 1.06 – 1.2 0.000299 1082 10576 all phecode
274.2 Crystal arthropathies Endocrine/metabolic 0.914 0.785 – 1.06 0.248 195 1890 all phecode
274.21 Chondrocalcinosis Endocrine/metabolic 0.907 0.775 – 1.06 0.227 183 1772 all phecode
275 Disorders of mineral metabolism Endocrine/metabolic 1.08 1.05 – 1.12 2.02e-06 4357 37091 all phecode
275.1 Disorders of iron metabolism Hematopoietic 0.899 0.782 – 1.03 0.136 218 2180 all phecode
275.11 Hereditary hemochromatosis Hematopoietic 0.924 0.752 – 1.13 0.448 99 990 all phecode
275.2 Disorders of copper metabolism Endocrine/metabolic 0.805 0.616 – 1.05 0.112 62 614 all phecode
275.3 Disorders of magnesium metabolism Endocrine/metabolic 1.15 1.08 – 1.22 1.8e-05 1154 11504 all phecode
275.5 Disorders of calcium/phosphorus metabolism Endocrine/metabolic 1.09 1.05 – 1.13 2.33e-06 3369 31544 all phecode
275.51 Hypocalcemia Endocrine/metabolic 1.09 1.01 – 1.17 0.0207 898 8969 all phecode
275.53 Disorders of phosphorus metabolism Endocrine/metabolic 1.14 1.08 – 1.21 5.35e-06 1366 13634 all phecode
275.6 Hypercalcemia Endocrine/metabolic 1.09 1.03 – 1.15 0.00299 1468 14183 all phecode
276
Disorders of fluid, electrolyte, and acid-base
Disorders of fluid, electrolyte, and acid-base balance
 Endocrine/metabolic 1.07 1.04 – 1.09 1.29e-07 9238 37046 all phecode
276.1 Electrolyte imbalance Endocrine/metabolic 1.1 1.07 – 1.13 1.16e-11 6352 34366 all phecode
276.11 Hyperosmolality and/or hypernatremia Endocrine/metabolic 1.2 1.1 – 1.32 6.56e-05 550 5434 all phecode
276.12 Hyposmolality and/or hyponatremia Endocrine/metabolic 1.1 1.05 – 1.15 1.03e-05 2514 23219 all phecode
276.13 Hyperpotassemia Endocrine/metabolic 1.1 1.06 – 1.14 2.4e-06 2992 25216 all phecode
276.14 Hypopotassemia Endocrine/metabolic 1.16 1.11 – 1.22 9.04e-11 2148 20909 all phecode
276.4 Acid-base balance disorder Endocrine/metabolic 1.11 1.06 – 1.17 6.67e-06 2086 20332 all phecode
276.41 Acidosis Endocrine/metabolic 1.12 1.06 – 1.18 1.26e-05 1788 17572 all phecode
276.42 Alkalosis Endocrine/metabolic 1.08 0.983 – 1.19 0.108 476 4741 all phecode
276.5 Hypovolemia Endocrine/metabolic 1.04 1.01 – 1.07 0.0172 4574 34527 all phecode
276.6 Fluid overload Endocrine/metabolic 1.18 1.12 – 1.25 5.77e-09 1384 13211 all phecode
276.8 Polydipsia Endocrine/metabolic 1.06 0.879 – 1.29 0.53 124 1240 all phecode
277 Other disorders of metabolism Endocrine/metabolic 1.03 0.998 – 1.07 0.0619 4112 35070 all phecode
277.2
Other disorders of purine and pyrimidine
Other disorders of purine and pyrimidine metabolism
 Endocrine/metabolic 1.09 0.979 – 1.21 0.119 403 3991 all phecode
277.4 Disorders of bilirubin excretion Endocrine/metabolic 0.974 0.899 – 1.05 0.512 720 7161 all phecode
277.5 Other disorders of lipoid metabolism Endocrine/metabolic 1.06 0.992 – 1.14 0.0819 936 9270 all phecode
277.51 Lipoprotein disorders Endocrine/metabolic 1.05 0.97 – 1.13 0.234 773 7668 all phecode
277.7 Dysmetabolic syndrome X Endocrine/metabolic 0.999 0.931 – 1.07 0.988 916 8359 all phecode
278 Overweight, obesity and other hyperalimentation Endocrine/metabolic 1.06 1.04 – 1.08 4.1e-10 19419 27331 all phecode
278.1 Obesity Endocrine/metabolic 1.08 1.05 – 1.1 7.59e-13 17129 27321 all phecode
278.11 Morbid obesity Endocrine/metabolic 1.1 1.07 – 1.13 1.08e-13 8280 27172 all phecode
278.3 Localized adiposity Endocrine/metabolic 0.977 0.868 – 1.1 0.694 324 3228 all phecode
278.4 Abnormal weight gain Endocrine/metabolic 1.04 0.996 – 1.09 0.0761 2104 17411 all phecode
279 Disorders involving the immune mechanism Endocrine/metabolic 1.03 0.987 – 1.07 0.189 2934 28612 all phecode
279.1 Immunity deficiency Endocrine/metabolic 1.02 0.959 – 1.09 0.517 1161 11571 all phecode
279.11 Deficiency of humoral immunity Endocrine/metabolic 1.15 1.02 – 1.29 0.0182 330 3278 all phecode
279.2 Autoimmune disease NEC Endocrine/metabolic 0.974 0.901 – 1.05 0.498 754 7516 all phecode
279.7 Other immunological findings Endocrine/metabolic 0.987 0.957 – 1.02 0.418 4885 36552 all phecode
279.8
Other specified disorders involving the immune
Other specified disorders involving the immune mechanism
 Endocrine/metabolic 0.994 0.912 – 1.08 0.898 601 5988 all phecode
280 Iron deficiency anemias Hematopoietic 1.05 1.02 – 1.08 0.00306 4626 30873 all phecode
280.1
Iron deficiency anemias, unspecified or not due
Iron deficiency anemias, unspecified or not due to blood loss
 Hematopoietic 1.05 1.02 – 1.09 0.00264 4484 30649 all phecode
280.2
Iron deficiency anemia secondary to blood loss
Iron deficiency anemia secondary to blood loss (chronic)
 Hematopoietic 1.06 1.01 – 1.11 0.0256 1771 17196 all phecode
281 Other deficiency anemia Hematopoietic 1.01 0.921 – 1.11 0.821 519 5120 all phecode
281.1 Megaloblastic anemia Hematopoietic 0.973 0.852 – 1.11 0.68 253 2497 all phecode
281.11 Pernicious anemia Hematopoietic 0.89 0.731 – 1.08 0.247 114 1108 all phecode
281.12 Other vitamin B12 deficiency anemia Hematopoietic 0.925 0.792 – 1.08 0.327 187 1817 all phecode
281.9 Deficiency anemias Hematopoietic 1.08 0.953 – 1.22 0.227 285 2830 all phecode
282 Hereditary hemolytic anemias Hematopoietic 1.02 0.905 – 1.15 0.754 323 3188 all phecode
282.8 Other hemoglobinopathies Hematopoietic 1.01 0.872 – 1.17 0.906 216 2113 all phecode
282.9 Other hereditary hemolytic anemias Hematopoietic 1.02 0.873 – 1.18 0.846 192 1920 all phecode
283 Acquired hemolytic anemias Hematopoietic 1.09 0.923 – 1.29 0.303 155 1550 all phecode
283.1 Autoimmune hemolytic anemias Hematopoietic 1.06 0.822 – 1.36 0.66 64 633 all phecode
284 Aplastic anemia Hematopoietic 1.01 0.936 – 1.1 0.736 697 6943 all phecode
284.1 Pancytopenia Hematopoietic 1.02 0.936 – 1.11 0.663 612 6100 all phecode
285 Other anemias Hematopoietic 1.02 1 – 1.05 0.035 11794 33591 all phecode
285.1 Acute posthemorrhagic anemia Hematopoietic 1.02 0.983 – 1.06 0.288 3325 27709 all phecode
285.2 Anemia of chronic disease Hematopoietic 1.09 1.05 – 1.15 0.000134 2055 19939 all phecode
285.21 Anemia in chronic kidney disease Hematopoietic 1.19 1.11 – 1.28 4.58e-07 932 9106 all phecode
285.22 Anemia in neoplastic disease Hematopoietic 0.968 0.893 – 1.05 0.436 690 6892 all phecode
286 Coagulation defects Hematopoietic 1.02 0.99 – 1.06 0.174 3844 33384 all phecode
286.1 Congenital coagulation defects Hematopoietic 1.03 0.903 – 1.18 0.649 250 2466 all phecode
286.11 Von willebrand's disease Hematopoietic 1.16 0.917 – 1.47 0.215 83 822 all phecode
286.12
Congenital deficiency of other clotting factors
Congenital deficiency of other clotting factors (including factor VII)
 Hematopoietic 1.01 0.833 – 1.22 0.943 126 1260 all phecode
286.2
Encounter for long-term (current) use of
Encounter for long-term (current) use of anticoagulants
 Hematopoietic 1.04 1 – 1.08 0.0501 3354 25918 all phecode
286.3
Coagulation defects complicating pregnancy or
Coagulation defects complicating pregnancy or postpartum
 Hematopoietic 1.2 0.969 – 1.48 0.0946 97 962 all phecode
286.4 Acquired coagulation factor deficiency Hematopoietic 1.04 0.912 – 1.19 0.542 254 2529 all phecode
286.5
Hemorrhagic disorder due to intrinsic
Hemorrhagic disorder due to intrinsic circulating anticoagulants
 Hematopoietic 1 0.839 – 1.19 0.999 132 1294 all phecode
286.6 Defibrination syndrome Hematopoietic 1.01 0.974 – 1.06 0.486 2579 25377 all phecode
286.7 Other and unspecified coagulation defects Hematopoietic 1.02 0.977 – 1.06 0.433 3014 29294 all phecode
286.8 Hypercoagulable state Hematopoietic 0.982 0.914 – 1.06 0.634 846 8437 all phecode
286.81 Primary hypercoagulable state Hematopoietic 0.968 0.898 – 1.04 0.385 813 8111 all phecode
286.9 Abnormal coagulation profile Hematopoietic 1.07 1 – 1.13 0.0398 1182 11487 all phecode
287 Purpura and other hemorrhagic conditions Hematopoietic 1.05 1.02 – 1.09 0.00556 3288 28474 all phecode
287.1 Spontaneous ecchymoses Hematopoietic 1.18 1.02 – 1.36 0.0219 211 2094 all phecode
287.3 Thrombocytopenia Hematopoietic 1.04 1 – 1.09 0.0294 2938 26323 all phecode
287.31 Primary thrombocytopenia Hematopoietic 1.12 1.02 – 1.22 0.0122 601 5994 all phecode
287.32 Secondary thrombocytopenia Hematopoietic 1.05 0.957 – 1.14 0.326 569 5686 all phecode
287.4 Qualitative platelet defects Hematopoietic 1.03 0.848 – 1.24 0.789 112 1120 all phecode
288 Diseases of white blood cells Hematopoietic 1.05 1.02 – 1.08 0.00306 4886 36527 all phecode
288.1 Decreased white blood cell count Hematopoietic 0.991 0.94 – 1.04 0.736 1599 15951 all phecode
288.11 Neutropenia Hematopoietic 0.998 0.937 – 1.06 0.959 1106 11041 all phecode
288.2 Elevated white blood cell count Hematopoietic 1.05 1.02 – 1.09 0.00304 4082 35079 all phecode
288.3 Eosinophilia Hematopoietic 1.02 0.873 – 1.19 0.82 187 1866 all phecode
289 Other diseases of blood and blood-forming organs Hematopoietic 1.02 0.965 – 1.07 0.549 1757 17434 all phecode
289.3
Personal history of diseases of blood and
Personal history of diseases of blood and blood-forming organs
 Hematopoietic 0.987 0.92 – 1.06 0.708 918 9087 all phecode
289.4 Lymphadenitis Hematopoietic 0.974 0.941 – 1.01 0.13 3888 34715 all phecode
289.5 Diseases of spleen Hematopoietic 1.01 0.905 – 1.12 0.893 393 3913 all phecode
289.8 Polycythemia, secondary Hematopoietic 1.02 0.897 – 1.17 0.728 255 2550 all phecode
289.9 Abnormality of red blood cells Hematopoietic 1 0.901 – 1.12 0.947 385 3813 all phecode
290
Delirium dementia and amnestic and other
Delirium dementia and amnestic and other cognitive disorders
 Mental Disorders 1.08 1.02 – 1.15 0.00969 1318 11547 all phecode
290.1 Dementias Mental Disorders 0.984 0.899 – 1.08 0.724 541 4910 all phecode
290.11 Alzheimer's disease Mental Disorders 0.922 0.779 – 1.09 0.347 151 1389 all phecode
290.12 Dementia with cerebral degenerations Mental Disorders 0.841 0.674 – 1.05 0.127 88 846 all phecode
290.13 Senile dementia Mental Disorders 1.05 0.933 – 1.17 0.444 340 3078 all phecode
290.16 Vascular dementia Mental Disorders 1.03 0.815 – 1.3 0.8 81 777 all phecode
290.2 Delirium due to conditions classified elsewhere Mental Disorders 1.13 1.05 – 1.22 0.00177 750 7358 all phecode
290.3
Other persistent mental disorders due to
Other persistent mental disorders due to conditions classified elsewhere
 Mental Disorders 0.96 0.895 – 1.03 0.262 886 8618 all phecode
291
Other specified nonpsychotic and/or transient
Other specified nonpsychotic and/or transient mental disorders
 Mental Disorders 1.02 0.979 – 1.06 0.328 2550 24810 all phecode
291.1
Transient mental disorders due to conditions
Transient mental disorders due to conditions classified elsewhere
 Mental Disorders 1.03 0.88 – 1.21 0.712 175 1750 all phecode
291.4
Specific nonpsychotic mental disorders due to
Specific nonpsychotic mental disorders due to brain damage
 Mental Disorders 0.915 0.831 – 1.01 0.0703 484 4807 all phecode
291.8 Alteration of consciousness Mental Disorders 1.03 0.98 – 1.07 0.277 2036 19974 all phecode
292 Neurological disorders Mental Disorders 1.04 1.01 – 1.07 0.0164 5733 38553 all phecode
292.1 Aphasia/speech disturbance Mental Disorders 1.05 0.998 – 1.1 0.0621 2013 19867 all phecode
292.11 Aphasia Mental Disorders 1.06 0.975 – 1.15 0.179 664 6581 all phecode
292.12 Symbolic dysfunction Mental Disorders 1.18 1.02 – 1.37 0.0262 200 1988 all phecode
292.2 Mild cognitive impairment Mental Disorders 0.882 0.792 – 0.981 0.021 389 3731 all phecode
292.3 Memory loss Mental Disorders 0.972 0.927 – 1.02 0.255 1922 18158 all phecode
292.4 Altered mental status Mental Disorders 1.07 1.02 – 1.11 0.00316 2454 22725 all phecode
292.5 Transient alteration of awareness Mental Disorders 1.06 0.958 – 1.17 0.258 430 4285 all phecode
292.6 Hallucinations Mental Disorders 1.07 0.928 – 1.23 0.355 217 2147 all phecode
293 Symptoms involving head and neck Mental Disorders 0.925 0.835 – 1.03 0.141 414 4127 all phecode
293.1
Swelling, mass, or lump in head and neck
Swelling, mass, or lump in head and neck [Space-occupying lesion, intracranial NOS]
 Mental Disorders 1.01 0.977 – 1.04 0.59 4417 38609 all phecode
295 Schizophrenia and other psychotic disorders Mental Disorders 0.976 0.908 – 1.05 0.511 885 8229 all phecode
295.1 Schizophrenia Mental Disorders 0.926 0.775 – 1.11 0.394 138 1339 all phecode
295.2 Paranoid disorders Mental Disorders 0.974 0.801 – 1.18 0.791 118 1079 all phecode
295.3 Psychosis Mental Disorders 0.997 0.92 – 1.08 0.944 716 6694 all phecode
296 Mood disorders Mental Disorders 1.01 0.984 – 1.03 0.634 15356 20858 all phecode
296.1 Bipolar Mental Disorders 1.01 0.948 – 1.07 0.847 1301 11264 all phecode
296.2 Depression Mental Disorders 1.01 0.983 – 1.03 0.639 14833 20856 all phecode
296.22 Major depressive disorder Mental Disorders 1 0.982 – 1.03 0.729 13850 20853 all phecode
297 Suicidal ideation or attempt Mental Disorders 1.08 1.01 – 1.16 0.0264 985 9050 all phecode
297.1 Suicidal ideation Mental Disorders 1.06 0.986 – 1.15 0.112 788 7310 all phecode
297.2 Suicide or self-inflicted injury Mental Disorders 1.08 0.947 – 1.22 0.265 285 2654 all phecode
300 Anxiety disorders Mental Disorders 0.999 0.977 – 1.02 0.923 15419 20850 all phecode
300.1 Anxiety disorder Mental Disorders 0.999 0.977 – 1.02 0.942 14517 20855 all phecode
300.11 Generalized anxiety disorder Mental Disorders 1 0.97 – 1.03 0.942 5546 20512 all phecode
300.12 Agorophobia, social phobia, and panic disorder Mental Disorders 1.02 0.956 – 1.08 0.617 1360 11377 all phecode
300.13 Phobia Mental Disorders 1.01 0.948 – 1.08 0.678 1051 9542 all phecode
300.3 Obsessive-compulsive disorders Mental Disorders 0.916 0.813 – 1.03 0.147 328 3018 all phecode
300.4 Dysthymic disorder Mental Disorders 0.966 0.924 – 1.01 0.127 2420 16552 all phecode
300.8 Acute reaction to stress Mental Disorders 0.991 0.903 – 1.09 0.851 504 4825 all phecode
300.9 Posttraumatic stress disorder Mental Disorders 1.04 0.969 – 1.12 0.257 843 7909 all phecode
301 Personality disorders Mental Disorders 1 0.912 – 1.11 0.92 477 4539 all phecode
301.2 Antisocial/borderline personality disorder Mental Disorders 0.95 0.833 – 1.08 0.449 254 2393 all phecode
302 Sexual and gender identity disorders Mental Disorders 0.987 0.949 – 1.03 0.493 3700 13808 all phecode
302.1 Decreased libido Mental Disorders 0.954 0.862 – 1.06 0.36 447 4331 all phecode
303 Psychogenic and somatoform disorders Mental Disorders 0.978 0.95 – 1.01 0.126 6808 20043 all phecode
303.1 Dissociative disorder Mental Disorders 1 0.854 – 1.18 0.972 161 1573 all phecode
303.3 Psychogenic disorder Mental Disorders 0.97 0.942 – 0.999 0.0399 6487 19888 all phecode
303.31
Gastrointestinal malfunction arising from
Gastrointestinal malfunction arising from mental factors
 Mental Disorders 0.895 0.813 – 0.986 0.0252 471 4623 all phecode
303.4 Somatoform disorder Mental Disorders 1.01 0.948 – 1.07 0.792 1177 11180 all phecode
304 Adjustment reaction Mental Disorders 0.982 0.947 – 1.02 0.304 3888 20475 all phecode
305.2 Eating disorder Mental Disorders 0.975 0.908 – 1.05 0.476 901 8329 all phecode
306 Other mental disorder Mental Disorders 0.95 0.904 – 0.999 0.0476 1815 14133 all phecode
306.1 Mental disorders durring/after pregnancy Mental Disorders 1 0.913 – 1.1 0.997 587 3527 all phecode
306.9 Tension headache Mental Disorders 0.955 0.884 – 1.03 0.236 753 7277 all phecode
312 Conduct disorders Mental Disorders 0.969 0.848 – 1.11 0.638 254 2501 all phecode
312.3 Impulse control disorder Mental Disorders 1.02 0.797 – 1.3 0.882 74 736 all phecode
313 Pervasive developmental disorders Mental Disorders 0.925 0.877 – 0.976 0.00437 1571 14633 all phecode
313.1 Attention deficit hyperactivity disorder Mental Disorders 0.918 0.867 – 0.972 0.00338 1392 13190 all phecode
313.2 Tics and stuttering Mental Disorders 1.03 0.814 – 1.3 0.802 77 770 all phecode
313.3 Autism Mental Disorders 0.983 0.762 – 1.27 0.892 64 621 all phecode
315 Develomental delays and disorders Mental Disorders 0.984 0.908 – 1.07 0.7 684 6788 all phecode
315.1 Learning disorder Mental Disorders 0.972 0.778 – 1.21 0.806 87 860 all phecode
315.2 Speech and language disorder Mental Disorders 0.957 0.838 – 1.09 0.519 254 2539 all phecode
316 Substance addiction and disorders Mental Disorders 1.03 0.999 – 1.07 0.0555 3682 32680 all phecode
316.1 Polyneuropathy due to drugs Mental Disorders 1.01 0.928 – 1.1 0.833 634 6331 all phecode
317 Alcohol-related disorders Mental Disorders 0.998 0.957 – 1.04 0.92 2525 22920 all phecode
317.1 Alcoholism Mental Disorders 0.999 0.953 – 1.05 0.963 1986 19339 all phecode
317.11 Alcoholic liver damage Mental Disorders 0.955 0.862 – 1.06 0.378 408 4080 all phecode
318 Tobacco use disorder Mental Disorders 1.03 1.01 – 1.06 0.0156 8622 34842 all phecode
320 Meningitis Neurological 1.01 0.906 – 1.12 0.915 382 3820 all phecode
323 Encephalitis Neurological 0.865 0.74 – 1.01 0.0686 181 1809 all phecode
323.8 Encephalitis, non-infectious Neurological 0.867 0.732 – 1.03 0.0959 153 1527 all phecode
324 Other CNS infection and poliomyelitis Neurological 0.954 0.843 – 1.08 0.451 288 2880 all phecode
325
Phlebitis and thrombophlebitis of intracranial
Phlebitis and thrombophlebitis of intracranial venous sinuses
 Neurological 1.02 0.759 – 1.36 0.917 53 530 all phecode
327 Sleep disorders Neurological 1.01 0.989 – 1.03 0.388 14941 31602 all phecode
327.1 Hypersomnia Neurological 0.945 0.901 – 0.99 0.0172 2061 19110 all phecode
327.3 Sleep apnea Neurological 1.02 0.996 – 1.04 0.0979 10909 31304 all phecode
327.31 Central/nonobstroctive sleep apnea Neurological 0.989 0.899 – 1.09 0.825 492 4784 all phecode
327.32 Obstructive sleep apnea Neurological 1.02 0.996 – 1.05 0.104 8744 30530 all phecode
327.4 Insomnia Neurological 0.967 0.939 – 0.997 0.0287 5524 30960 all phecode
327.41 Organic or persistent insomnia Neurological 0.944 0.89 – 1 0.0591 1265 12120 all phecode
327.5 Parasomnia Neurological 1.01 0.927 – 1.1 0.835 604 5913 all phecode
327.6 Circadian rhythm sleep disorder Neurological 0.946 0.832 – 1.08 0.396 274 2666 all phecode
327.7 Sleep related movement disorders Neurological 1.03 0.976 – 1.08 0.31 1786 17323 all phecode
327.71 Restless legs syndrome Neurological 1.04 0.987 – 1.1 0.142 1570 15360 all phecode
327.72 Sleep related leg cramps Neurological 0.954 0.757 – 1.2 0.687 83 822 all phecode
331 Other cerebral degenerations Neurological 1.04 0.96 – 1.13 0.341 717 7024 all phecode
331.1 Hydrocephalus Neurological 1.08 0.949 – 1.22 0.253 284 2836 all phecode
331.9 Cerebral degeneration, unspecified Neurological 1.01 0.909 – 1.12 0.874 419 4026 all phecode
332 Parkinson's disease Neurological 1.03 0.927 – 1.14 0.587 415 4128 all phecode
333
Extrapyramidal disease and abnormal movement
Extrapyramidal disease and abnormal movement disorders
 Neurological 1.02 0.984 – 1.06 0.252 2868 26583 all phecode
333.1 Essential tremor Neurological 0.963 0.89 – 1.04 0.35 725 7163 all phecode
333.2 Myoclonus Neurological 1.17 0.994 – 1.39 0.0591 159 1590 all phecode
333.4 Torsion dystonia Neurological 1 0.896 – 1.13 0.936 352 3504 all phecode
333.8 Other degenerative diseases of the basal ganglia Neurological 0.95 0.764 – 1.18 0.647 89 890 all phecode
334 Degenerative disease of the spinal cord Neurological 1.02 0.958 – 1.09 0.498 1058 10562 all phecode
334.1 Spinocerebellar disease Neurological 1.02 0.807 – 1.29 0.866 79 790 all phecode
334.2 Anterior horn cell disease Neurological 1.09 0.891 – 1.34 0.393 110 1080 all phecode
334.21 Amyotrophic Lateral Sclerosis Neurological 1.02 0.788 – 1.32 0.889 71 693 all phecode
335 Multiple sclerosis Neurological 1 0.903 – 1.11 0.955 396 3951 all phecode
337 Disorders of the autonomic nervous system Neurological 1.05 0.974 – 1.13 0.21 808 7413 all phecode
337.1 Peripheral autonomic neuropathy Neurological 1.06 0.947 – 1.19 0.316 370 3164 all phecode
338 Pain Neurological 0.993 0.975 – 1.01 0.488 20346 26417 all phecode
338.1 Acute pain Neurological 0.993 0.973 – 1.01 0.526 15582 26313 all phecode
338.2 Chronic pain Neurological 0.989 0.966 – 1.01 0.34 10994 26368 all phecode
339 Other headache syndromes Neurological 1 0.978 – 1.03 0.903 9242 34658 all phecode
340 Migraine Neurological 0.993 0.965 – 1.02 0.599 6708 30587 all phecode
340.1 Migrain with aura Neurological 0.972 0.938 – 1.01 0.122 3624 23684 all phecode
341
Other demyelinating diseases of central nervous
Other demyelinating diseases of central nervous system
 Neurological 1.07 0.893 – 1.27 0.475 133 1330 all phecode
342 Hemiplegia Neurological 1.1 0.999 – 1.21 0.053 464 4607 all phecode
343 Infantile cerebral palsy Neurological 0.883 0.705 – 1.11 0.276 85 847 all phecode
344 Other paralytic syndromes Neurological 1.03 0.949 – 1.12 0.487 682 6808 all phecode
345 Epilepsy, recurrent seizures, convulsions Neurological 1.02 0.981 – 1.07 0.291 2553 25307 all phecode
345.1 Epilepsy Neurological 1.05 0.972 – 1.13 0.216 747 7465 all phecode
345.11 Generalized convulsive epilepsy Neurological 1.07 0.933 – 1.22 0.347 233 2330 all phecode
345.12 Partial epilepsy Neurological 1.03 0.942 – 1.13 0.504 534 5335 all phecode
345.3 Convulsions Neurological 1.02 0.982 – 1.07 0.263 2396 23796 all phecode
346
Abnormal findings on study of brain and/or
Abnormal findings on study of brain and/or nervous system
 Neurological 0.942 0.809 – 1.1 0.446 183 1824 all phecode
346.1
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of skull and head
 Neurological 1.02 0.965 – 1.08 0.493 1472 14587 all phecode
346.2
Nonspecific abnormal results of function study
Nonspecific abnormal results of function study of brain and central nervous system
 Neurological 1.01 0.838 – 1.22 0.9 120 1181 all phecode
346.3
Nonspecific abnormal findings in cerebrospinal
Nonspecific abnormal findings in cerebrospinal fluid
 Neurological 1.03 0.841 – 1.26 0.787 110 1100 all phecode
347 Cataplexy and narcolepsy Neurological 1.11 0.898 – 1.36 0.344 101 1010 all phecode
348 Other conditions of brain Neurological 1.06 1.01 – 1.11 0.0207 1793 17894 all phecode
348.2 Cerebral edema and compression of brain Neurological 1.03 0.962 – 1.11 0.375 905 9034 all phecode
348.4 Cerebral cysts Neurological 0.978 0.85 – 1.12 0.753 229 2290 all phecode
348.7 Coma Neurological 1.05 0.917 – 1.21 0.458 229 2275 all phecode
348.8 Encephalopathy, not elsewhere classified Neurological 1.11 1.03 – 1.19 0.0051 853 8479 all phecode
348.9 Other conditions of brain, NOS Neurological 1.01 0.97 – 1.06 0.54 2341 23287 all phecode
349
Other and unspecified disorders of the nervous
Other and unspecified disorders of the nervous system
 Neurological 1 0.935 – 1.07 0.968 941 9385 all phecode
350 Abnormal movement Neurological 1.01 0.98 – 1.03 0.625 6706 38762 all phecode
350.1 Abnormal involuntary movements Neurological 1 0.968 – 1.04 0.816 3273 30524 all phecode
350.2 Abnormality of gait Neurological 0.993 0.96 – 1.03 0.701 3920 30520 all phecode
350.3 Lack of coordination Neurological 0.993 0.931 – 1.06 0.829 1062 10554 all phecode
350.5 Abnormal reflex Neurological 1.02 0.879 – 1.18 0.803 200 1988 all phecode
350.6 Disturbances of sensation of smell and taste Neurological 0.989 0.905 – 1.08 0.802 558 5576 all phecode
351 Other peripheral nerve disorders Neurological 0.999 0.973 – 1.03 0.917 7401 34460 all phecode
352 Disorders of other cranial nerves Neurological 1.02 0.966 – 1.07 0.517 1714 17106 all phecode
352.1 Trigeminal nerve disorders [CN5] Neurological 1.02 0.934 – 1.12 0.607 535 5344 all phecode
352.2 Facial nerve disorders [CN7] Neurological 0.962 0.892 – 1.04 0.315 783 7826 all phecode
353 Nerve root and plexus disorders Neurological 0.983 0.952 – 1.02 0.317 4256 33369 all phecode
353.1 Nerve plexus lesions Neurological 1.03 0.924 – 1.14 0.62 390 3900 all phecode
353.2 Nerve root lesions Neurological 1.08 0.895 – 1.3 0.424 130 1287 all phecode
355 Complex regional/central pain syndrome Neurological 1.02 0.927 – 1.11 0.745 531 5295 all phecode
355.1 Chronic pain syndrome Neurological 1.04 0.963 – 1.11 0.346 843 8386 all phecode
356 Hereditary and idiopathic peripheral neuropathy Neurological 1 0.958 – 1.05 0.96 2335 20731 all phecode
357 Inflammatory and toxic neuropathy Neurological 1 0.965 – 1.04 0.984 3472 29956 all phecode
358 Myoneural disorders Neurological 0.997 0.937 – 1.06 0.922 1147 11391 all phecode
358.1 Myasthenia gravis Neurological 1.01 0.824 – 1.24 0.914 109 1082 all phecode
359 Muscular dystrophies and other myopathies Neurological 0.98 0.92 – 1.04 0.534 1134 11274 all phecode
359.1 Muscular dystrophies Neurological 0.921 0.719 – 1.18 0.517 64 632 all phecode
359.2 Myopathy Neurological 0.987 0.926 – 1.05 0.694 1092 10843 all phecode
360 Disorders of the globe Sense Organs 0.953 0.79 – 1.15 0.614 131 1276 all phecode
360.2 Progressive myopia Sense Organs 0.802 0.616 – 1.04 0.101 65 640 all phecode
361 Retinal detachments and defects Sense Organs 0.989 0.914 – 1.07 0.779 733 7131 all phecode
361.1 Retinal detachment with retinal defect Sense Organs 1.03 0.906 – 1.16 0.687 302 2962 all phecode
362 Other retinal disorders Sense Organs 1 0.964 – 1.04 0.966 3569 22997 all phecode
362.2
Degeneration of macula and posterior pole of
Degeneration of macula and posterior pole of retina
 Sense Organs 0.964 0.92 – 1.01 0.128 2172 15483 all phecode
362.21 Macular degeneration, dry Sense Organs 0.95 0.854 – 1.06 0.35 419 3438 all phecode
362.22 Macular degeneration, wet Sense Organs 0.991 0.824 – 1.19 0.921 148 1184 all phecode
362.23 Cystoid macular degeneration of retina Sense Organs 1.07 0.966 – 1.2 0.187 408 3839 all phecode
362.26 Macular puckering of retina Sense Organs 0.986 0.92 – 1.06 0.676 976 8610 all phecode
362.27 Drusen (degenerative) of retina Sense Organs 0.964 0.875 – 1.06 0.461 488 4558 all phecode
362.29 Macular degeneration (senile) of retina NOS Sense Organs 0.961 0.914 – 1.01 0.119 1883 13955 all phecode
362.3 Other nondiabetic retinopathy Sense Organs 1.13 1.05 – 1.21 0.000665 976 8527 all phecode
362.31 Separation of retinal layers Sense Organs 0.976 0.878 – 1.08 0.645 413 4056 all phecode
362.4 Retinal vascular changes and abnomalities Sense Organs 1.04 0.957 – 1.13 0.347 662 5933 all phecode
362.6 Peripheral retinal degenerations Sense Organs 0.978 0.877 – 1.09 0.686 392 3787 all phecode
362.7 Hereditary retinal dystrophies Sense Organs 0.995 0.861 – 1.15 0.943 215 2103 all phecode
362.8 Retinal hemorrhage/ischemia Sense Organs 1.04 0.909 – 1.19 0.556 241 2368 all phecode
362.9 Retinal edema Sense Organs 1.15 1.02 – 1.29 0.0218 324 2936 all phecode
363
Chorioretinal inflammations, scars, and other
Chorioretinal inflammations, scars, and other disorders of choroid
 Sense Organs 1 0.912 – 1.1 0.942 492 4746 all phecode
363.3 Chorioretinal scars Sense Organs 0.998 0.888 – 1.12 0.97 332 3184 all phecode
364 Corneal opacity and other disorders of cornea Sense Organs 0.971 0.912 – 1.03 0.369 1132 10772 all phecode
364.1 Corneal opacity Sense Organs 0.94 0.845 – 1.05 0.258 394 3846 all phecode
364.2 Corneal edema Sense Organs 1.11 0.916 – 1.34 0.29 123 1208 all phecode
364.4 Corneal degenerations Sense Organs 1 0.9 – 1.11 0.999 402 3962 all phecode
364.41 Keratoconus Sense Organs 1.32 1.04 – 1.68 0.0235 75 739 all phecode
364.5 Corneal dystrophy Sense Organs 0.988 0.898 – 1.09 0.808 502 4682 all phecode
364.51 Fuchs' dystrophy Sense Organs 1 0.881 – 1.15 0.945 266 2521 all phecode
364.9 Cornea replaced by transplant Sense Organs 0.945 0.755 – 1.18 0.621 91 885 all phecode
365 Glaucoma Sense Organs 1.02 0.975 – 1.06 0.444 2672 21326 all phecode
365.1 Open-angle glaucoma Sense Organs 0.999 0.922 – 1.08 0.977 705 6491 all phecode
365.11 Primary open angle glaucoma Sense Organs 0.991 0.891 – 1.1 0.875 403 3681 all phecode
365.2 Primary angle-closure glaucoma Sense Organs 0.928 0.812 – 1.06 0.268 251 2370 all phecode
366 Cataract Sense Organs 1 0.974 – 1.03 0.966 8611 28043 all phecode
366.1 Nonsenile Cataract Sense Organs 1.04 0.893 – 1.21 0.63 207 1979 all phecode
366.2 Senile cataract Sense Organs 1 0.974 – 1.04 0.758 5480 24980 all phecode
367
Disorders of refraction and accommodation
Disorders of refraction and accommodation; blindness and low vision
 Sense Organs 0.988 0.964 – 1.01 0.313 8967 37779 all phecode
367.1 Myopia Sense Organs 0.986 0.956 – 1.02 0.384 5014 34677 all phecode
367.2 Astigmatism Sense Organs 0.969 0.937 – 1 0.0631 4161 32463 all phecode
367.8 Hypermetropia Sense Organs 0.971 0.926 – 1.02 0.217 2039 18599 all phecode
367.9 Blindness and low vision Sense Organs 0.966 0.91 – 1.03 0.252 1277 12356 all phecode
368 Visual disturbances Sense Organs 1 0.976 – 1.03 0.764 5715 39599 all phecode
368.1 Amblyopia Sense Organs 1.05 0.966 – 1.14 0.248 651 6479 all phecode
368.2 Diplopia and disorders of binocular vision Sense Organs 0.991 0.93 – 1.06 0.792 1087 10786 all phecode
368.3 Anisometropia Sense Organs 0.951 0.823 – 1.1 0.491 219 2168 all phecode
368.4 Visual field defects Sense Organs 0.987 0.927 – 1.05 0.689 1132 11173 all phecode
368.9 Subjective visual disturbances Sense Organs 0.985 0.924 – 1.05 0.653 1070 10620 all phecode
368.91 Psychophysical visual disturbances Sense Organs 1.1 0.908 – 1.33 0.332 120 1171 all phecode
369 Infection of the eye Sense Organs 0.943 0.908 – 0.979 0.00232 3185 28240 all phecode
369.2 Eye infection, viral Sense Organs 0.909 0.826 – 1 0.0512 502 4954 all phecode
369.5 Conjunctivitis, infectious Sense Organs 0.949 0.911 – 0.989 0.012 2716 24970 all phecode
370 Keratitis Sense Organs 0.952 0.899 – 1.01 0.0919 1365 13169 all phecode
370.1 Corneal ulcer Sense Organs 0.929 0.805 – 1.07 0.313 223 2194 all phecode
370.2 Superficial keratitis Sense Organs 0.873 0.797 – 0.955 0.00325 546 5393 all phecode
370.3 Keratoconjunctivitis Sense Organs 0.988 0.909 – 1.07 0.782 649 6263 all phecode
370.31 Keratoconjunctivitis sicca Sense Organs 0.91 0.778 – 1.07 0.24 179 1677 all phecode
371 Inflammation of the eye Sense Organs 0.961 0.93 – 0.992 0.0158 4414 32310 all phecode
371.1 Uveitis, noninfectious or NOS Sense Organs 0.95 0.867 – 1.04 0.275 541 5278 all phecode
371.2 Conjunctivitis, noninfectious Sense Organs 0.945 0.88 – 1.01 0.116 906 8939 all phecode
371.21 Allergic conjunctivitis Sense Organs 0.959 0.888 – 1.04 0.284 756 7515 all phecode
371.3 Inflammation of eyelids Sense Organs 0.957 0.922 – 0.993 0.0196 3398 26983 all phecode
371.33 Noninfectious dermatoses of eyelid Sense Organs 0.854 0.709 – 1.03 0.0946 133 1291 all phecode
372 Disorders of conjunctiva Sense Organs 1 0.939 – 1.07 0.992 1118 10728 all phecode
374 Other disorders of eyelids Sense Organs 0.982 0.944 – 1.02 0.367 2940 24188 all phecode
374.1 Ectropion or entropion Sense Organs 0.958 0.865 – 1.06 0.412 431 4084 all phecode
374.2 Lagophthalmos Sense Organs 0.981 0.856 – 1.12 0.779 235 2335 all phecode
374.3 Ptosis of eyelid Sense Organs 1 0.942 – 1.07 0.905 1102 10734 all phecode
374.6 Dermatochalasis Sense Organs 0.956 0.895 – 1.02 0.18 1040 9720 all phecode
375 Disorders of lacrimal system Sense Organs 0.975 0.941 – 1.01 0.17 3694 26045 all phecode
375.1 Dry eyes Sense Organs 0.967 0.935 – 1 0.0608 4040 26751 all phecode
375.2 Epiphora Sense Organs 0.97 0.875 – 1.07 0.554 442 4354 all phecode
376 Disorders of the orbit Sense Organs 1.01 0.903 – 1.13 0.884 352 3508 all phecode
377 Disorders of optic nerve and visual pathways Sense Organs 1.06 0.985 – 1.13 0.123 913 9021 all phecode
377.1 Optic atrophy Sense Organs 1.03 0.907 – 1.17 0.654 283 2793 all phecode
377.3 Optic neuritis/neuropathy Sense Organs 1.06 0.971 – 1.16 0.191 585 5775 all phecode
378
Strabismus and other disorders of binocular eye
Strabismus and other disorders of binocular eye movements
 Sense Organs 0.957 0.902 – 1.01 0.141 1275 12460 all phecode
378.1 Strabismus (not specified as paralytic) Sense Organs 0.961 0.893 – 1.03 0.286 828 8130 all phecode
378.2 Nystagmus and other irregular eye movements Sense Organs 1.01 0.863 – 1.19 0.881 170 1686 all phecode
378.5 Paralytic strabismus Sense Organs 0.969 0.865 – 1.09 0.585 349 3437 all phecode
379 Other disorders of eye Sense Organs 0.989 0.958 – 1.02 0.495 5046 29999 all phecode
379.1 Scleritis and episcleritis Sense Organs 1.16 0.99 – 1.36 0.0667 176 1743 all phecode
379.2 Disorders of vitreous body Sense Organs 0.98 0.945 – 1.02 0.289 3634 23186 all phecode
379.3 Aphakia and other disorders of lens Sense Organs 0.921 0.768 – 1.1 0.372 135 1258 all phecode
379.4 Anomalies of pupillary function Sense Organs 1.02 0.9 – 1.15 0.762 287 2833 all phecode
379.5 Disorders of iris and ciliary body Sense Organs 1.07 0.943 – 1.21 0.304 304 2948 all phecode
379.51 Pigmentary iris degeneration Sense Organs 1.08 0.853 – 1.37 0.52 77 731 all phecode
379.9 Pain, swelling or discharge of eye Sense Organs 0.966 0.907 – 1.03 0.286 1129 11130 all phecode
380 Disorders of external ear Sense Organs 0.912 0.872 – 0.953 5.04e-05 2242 20393 all phecode
380.1 Otitis externa Sense Organs 0.967 0.915 – 1.02 0.228 1469 14580 all phecode
380.4 Impacted cerumen Sense Organs 0.923 0.885 – 0.962 0.000141 2648 23557 all phecode
381 Otitis media and Eustachian tube disorders Sense Organs 0.984 0.952 – 1.02 0.327 4255 36417 all phecode
381.1 Otitis media Sense Organs 1 0.963 – 1.04 0.971 3079 29813 all phecode
381.11 Suppurative and unspecified otitis media Sense Organs 1 0.963 – 1.05 0.872 2610 25602 all phecode
381.2 Eustachian tube disorders Sense Organs 0.942 0.897 – 0.99 0.0189 1816 17827 all phecode
381.3 Mastoiditis & related conditions Sense Organs 1.08 0.913 – 1.28 0.369 153 1530 all phecode
381.9 Otorrhea Sense Organs 1.07 0.957 – 1.19 0.241 372 3713 all phecode
382 Otalgia Sense Organs 0.949 0.904 – 0.996 0.0341 1884 18673 all phecode
383 Otosclerosis Sense Organs 0.767 0.634 – 0.928 0.00629 124 1240 all phecode
384 Other disorders of tympanic membrane Sense Organs 0.927 0.845 – 1.02 0.108 516 5156 all phecode
384.1 Myringitis Sense Organs 0.679 0.507 – 0.91 0.00945 51 502 all phecode
384.4 Perforation of tympanic membrane Sense Organs 0.978 0.881 – 1.09 0.676 403 4029 all phecode
385 Other disorders of middle ear and mastoid Sense Organs 0.939 0.849 – 1.04 0.226 432 4320 all phecode
385.3 Cholesteatoma Sense Organs 0.948 0.838 – 1.07 0.4 277 2770 all phecode
385.5
Tympanosclerosis and middle ear disease related
Tympanosclerosis and middle ear disease related to otitis media
 Sense Organs 0.967 0.795 – 1.18 0.737 118 1180 all phecode
386
Vertiginous syndromes and other disorders of
Vertiginous syndromes and other disorders of vestibular system
 Sense Organs 0.974 0.928 – 1.02 0.284 1882 18186 all phecode
386.1 Meniere's disease Sense Organs 0.923 0.82 – 1.04 0.184 319 3156 all phecode
386.2 Peripheral or central vertigo Sense Organs 0.979 0.929 – 1.03 0.429 1586 15423 all phecode
386.21 Central origin vertigo Sense Organs 1 0.941 – 1.06 0.984 1208 11844 all phecode
386.3 Labyrinthitis Sense Organs 0.995 0.941 – 1.05 0.846 1482 14530 all phecode
386.9
Dizziness and giddiness (Light-headedness and
Dizziness and giddiness (Light-headedness and vertigo)
 Sense Organs 0.978 0.952 – 1 0.098 6933 38286 all phecode
388 Other disorders of ear Sense Organs 0.878 0.821 – 0.939 0.000158 960 9501 all phecode
389 Hearing loss Sense Organs 0.965 0.941 – 0.99 0.00543 8182 38069 all phecode
389.1 Sensorineural hearing loss Sense Organs 0.952 0.92 – 0.984 0.00389 4107 29258 all phecode
389.2 Conductive hearing loss Sense Organs 0.967 0.902 – 1.04 0.35 905 9042 all phecode
389.3 Degenerative and vascular disorders of ear Sense Organs 0.952 0.821 – 1.11 0.522 192 1808 all phecode
389.4 Tinnitus Sense Organs 0.931 0.891 – 0.973 0.00147 2291 22130 all phecode
389.5 Disorders of acoustic nerve Sense Organs 0.983 0.816 – 1.18 0.852 124 1229 all phecode
394 Rheumatic disease of the heart valves Circulatory System 1.07 1.01 – 1.13 0.0211 1458 13732 all phecode
394.1 Mitral valve stenosis and aortic valve stenosis Circulatory System 1.06 0.942 – 1.19 0.344 350 3415 all phecode
394.2 Mitral valve disease Circulatory System 1.05 0.949 – 1.16 0.355 462 4560 all phecode
394.3 Aortic valve disease Circulatory System 0.899 0.765 – 1.06 0.193 176 1691 all phecode
394.4 Acute rheumatic heart disease Circulatory System 1.34 1.02 – 1.76 0.0384 55 546 all phecode
394.7 Disease of tricuspid valve Circulatory System 1.1 1.01 – 1.21 0.0272 587 5739 all phecode
395 Heart valve disorders Circulatory System 1.08 1.05 – 1.12 4.39e-06 3976 28748 all phecode
395.1 Nonrheumatic mitral valve disorders Circulatory System 1.07 1.03 – 1.12 0.00241 2175 20441 all phecode
395.2 Nonrheumatic aortic valve disorders Circulatory System 1.09 1.04 – 1.14 0.000336 2060 17194 all phecode
395.3 Nonrheumatic tricuspid valve disorders Circulatory System 1.1 1 – 1.21 0.0472 493 4864 all phecode
395.4 Nonrheumatic pulmonary valve disorders Circulatory System 1.08 0.886 – 1.33 0.434 108 1080 all phecode
395.6 Heart valve replaced Circulatory System 1.04 0.981 – 1.11 0.172 1177 10833 all phecode
396 Abnormal heart sounds Circulatory System 1.07 1.04 – 1.11 7.9e-06 4718 34395 all phecode
401 Hypertension Circulatory System 1.52 1.48 – 1.55 8.15e-297 23317 23367 all phecode
401.1 Essential hypertension Circulatory System 1.52 1.49 – 1.56 3.34e-298 23158 23364 all phecode
401.2 Hypertensive heart and/or renal disease Circulatory System 1.61 1.54 – 1.68 2e-104 3503 14616 all phecode
401.21 Hypertensive heart disease Circulatory System 1.67 1.54 – 1.8 1.11e-38 893 6607 all phecode
401.22 Hypertensive chronic kidney disease Circulatory System 1.61 1.54 – 1.69 3.51e-86 2584 13072 all phecode
401.3 Other hypertensive complications Circulatory System 1.62 1.55 – 1.7 4.97e-98 2679 15833 all phecode
411 Ischemic Heart Disease Circulatory System 1.11 1.09 – 1.14 2.24e-16 8807 30299 all phecode
411.1 Unstable angina (intermediate coronary syndrome) Circulatory System 1.17 1.09 – 1.25 9.62e-06 937 8574 all phecode
411.2 Myocardial infarction Circulatory System 1.17 1.13 – 1.22 2.8e-17 3594 21716 all phecode
411.3 Angina pectoris Circulatory System 1.15 1.1 – 1.2 2.91e-10 2485 18304 all phecode
411.4 Coronary atherosclerosis Circulatory System 1.14 1.1 – 1.17 3.51e-19 7555 27492 all phecode
411.41 Aneurysm and dissection of heart Circulatory System 1.07 0.904 – 1.26 0.445 156 1529 all phecode
411.8
Other chronic ischemic heart disease
Other chronic ischemic heart disease, unspecified
 Circulatory System 1.16 1.13 – 1.2 1.18e-22 6331 25741 all phecode
411.9
Other acute and subacute forms of ischemic
Other acute and subacute forms of ischemic heart disease
 Circulatory System 1.14 1.03 – 1.26 0.0108 442 4211 all phecode
414 Other forms of chronic heart disease Circulatory System 1.08 1.04 – 1.13 5.13e-05 3101 22616 all phecode
414.2 ASCVD Circulatory System 1.14 1.06 – 1.24 0.000842 718 6816 all phecode
415 Pulmonary heart disease Circulatory System 1.04 1.01 – 1.08 0.025 3366 30208 all phecode
415.1 Acute pulmonary heart disease Circulatory System 0.978 0.932 – 1.03 0.376 1912 19014 all phecode
415.11 Pulmonary embolism and infarction, acute Circulatory System 0.979 0.933 – 1.03 0.394 1906 18953 all phecode
415.2 Chronic pulmonary heart disease Circulatory System 1.15 1.1 – 1.21 1.78e-08 1808 17605 all phecode
415.21 Primary pulmonary hypertension Circulatory System 1.17 1.08 – 1.27 7.37e-05 706 7032 all phecode
416 Cardiomegaly Circulatory System 1.09 1.03 – 1.16 0.0038 1254 12372 all phecode
418 Nonspecific chest pain Circulatory System 1.01 0.989 – 1.03 0.359 12650 33952 all phecode
418.1 Precordial pain Circulatory System 1.05 0.993 – 1.11 0.086 1471 13782 all phecode
420 Carditis Circulatory System 1.03 0.974 – 1.08 0.318 1588 15680 all phecode
420.1 Myocarditis Circulatory System 1.03 0.835 – 1.27 0.79 97 958 all phecode
420.2 Pericarditis Circulatory System 1.05 0.973 – 1.13 0.217 842 8402 all phecode
420.21 Acute pericarditis Circulatory System 1.02 0.875 – 1.2 0.77 177 1764 all phecode
420.22 Chronic pericarditis Circulatory System 1.2 0.988 – 1.46 0.0663 117 1153 all phecode
420.3 Endocarditis Circulatory System 1.03 0.952 – 1.11 0.486 764 7535 all phecode
425 Cardiomyopathy Circulatory System 1.09 1.04 – 1.14 0.000308 2078 19881 all phecode
425.1 Primary/intrinsic cardiomyopathies Circulatory System 1.08 1.03 – 1.14 0.000782 1989 19025 all phecode
425.11 Hypertrophic obstructive cardiomyopathy Circulatory System 1.13 0.981 – 1.31 0.0894 208 2050 all phecode
425.12 Other hypertrophic cardiomyopathy Circulatory System 1.07 0.923 – 1.25 0.355 201 1992 all phecode
425.2 Secondary/extrinsic cardiomyopathies Circulatory System 1.1 0.979 – 1.24 0.106 317 3170 all phecode
425.8 Other cardiomyopathy Circulatory System 1.3 1.04 – 1.62 0.0188 95 931 all phecode
426 Cardiac conduction disorders Circulatory System 1.04 1.01 – 1.06 0.00258 12327 25440 all phecode
426.2 Atrioventricular [AV] block Circulatory System 1.02 0.973 – 1.08 0.362 1903 11501 all phecode
426.21 First degree AV block Circulatory System 1.05 0.99 – 1.12 0.101 1313 8899 all phecode
426.22 Mobitz II AV block Circulatory System 1.18 0.913 – 1.53 0.207 64 553 all phecode
426.23 Second degree AV block Circulatory System 1.05 0.91 – 1.21 0.505 216 1925 all phecode
426.24 Atrioventricular block, complete Circulatory System 1.07 0.969 – 1.18 0.179 461 3823 all phecode
426.25 Other heart block Circulatory System 0.897 0.775 – 1.04 0.143 203 1803 all phecode
426.3 Bundle branch block Circulatory System 1.05 1 – 1.1 0.0513 2306 13999 all phecode
426.31 Right bundle branch block Circulatory System 1.02 0.964 – 1.08 0.496 1423 10758 all phecode
426.32 Left bundle branch block Circulatory System 1.07 1 – 1.15 0.0443 969 8110 all phecode
426.4 Anomalous atrioventricular excitation Circulatory System 1.02 0.814 – 1.27 0.875 82 820 all phecode
426.7 Abnormal electrocardiogram [ECG] [EKG] Circulatory System 1.04 1.02 – 1.07 0.000632 10577 25186 all phecode
426.8 Other cardiac conduction disorders Circulatory System 1.14 1.06 – 1.24 0.000964 679 6650 all phecode
426.9 Cardiac pacemaker/device in situ Circulatory System 1.06 1.01 – 1.12 0.0251 1754 11536 all phecode
426.91 Cardiac pacemaker in situ Circulatory System 1.08 1.01 – 1.15 0.0171 1171 8184 all phecode
426.92 Cardiac defibrillator in situ Circulatory System 1.1 1.02 – 1.19 0.00988 846 7320 all phecode
427 Cardiac dysrhythmias Circulatory System 1.02 0.999 – 1.04 0.0594 17397 25735 all phecode
427.1 Paroxysmal tachycardia, unspecified Circulatory System 1.02 0.976 – 1.06 0.402 2474 18178 all phecode
427.11 Paroxysmal supraventricular tachycardia Circulatory System 0.995 0.944 – 1.05 0.856 1595 14293 all phecode
427.12 Paroxysmal ventricular tachycardia Circulatory System 1.06 0.996 – 1.13 0.0691 1181 9915 all phecode
427.2 Atrial fibrillation and flutter Circulatory System 1.03 0.992 – 1.06 0.145 5313 18688 all phecode
427.21 Atrial fibrillation Circulatory System 1.02 0.988 – 1.06 0.208 5188 18409 all phecode
427.22 Atrial flutter Circulatory System 1.03 0.975 – 1.08 0.313 1693 11042 all phecode
427.3 Other specified cardiac dysrhythmias Circulatory System 1.04 1.01 – 1.06 0.00575 8688 25552 all phecode
427.4 Cardiac arrest and ventricular fibrillation Circulatory System 1.12 1.02 – 1.23 0.0151 536 5233 all phecode
427.41 Ventricular fibrillation and flutter Circulatory System 1.01 0.872 – 1.16 0.939 216 2118 all phecode
427.42 Cardiac arrest Circulatory System 1.2 1.08 – 1.33 0.000715 410 4034 all phecode
427.5 Arrhythmia (cardiac) NOS Circulatory System 1.03 1 – 1.06 0.0381 6905 25457 all phecode
427.6 Premature beats Circulatory System 1.02 0.978 – 1.07 0.318 2359 16248 all phecode
427.61 Supraventricular premature beats Circulatory System 1.03 0.952 – 1.12 0.439 670 6287 all phecode
427.7 Tachycardia NOS Circulatory System 1.03 0.997 – 1.06 0.0721 5124 25531 all phecode
427.8 Sinoatrial node dysfunction (Bradycardia) Circulatory System 0.99 0.922 – 1.06 0.787 912 7501 all phecode
427.9 Palpitations Circulatory System 1.01 0.973 – 1.04 0.716 4430 24505 all phecode
428 Congestive heart failure; nonhypertensive Circulatory System 1.12 1.08 – 1.16 4.17e-11 4300 23663 all phecode
428.1 Congestive heart failure (CHF) NOS Circulatory System 1.13 1.09 – 1.17 1.15e-10 3756 22446 all phecode
428.2 Heart failure NOS Circulatory System 1.14 1.1 – 1.18 1.4e-12 3701 21722 all phecode
428.3
Heart failure with reduced EF [Systolic or
Heart failure with reduced EF [Systolic or combined heart failure]
 Circulatory System 1.14 1.09 – 1.2 2.92e-07 1765 14476 all phecode
428.4
Heart failure with preserved EF [Diastolic
Heart failure with preserved EF [Diastolic heart failure]
 Circulatory System 1.19 1.13 – 1.25 2.06e-10 1648 13395 all phecode
429
Ill-defined descriptions and complications of
Ill-defined descriptions and complications of heart disease
 Circulatory System 1.04 1.02 – 1.07 9.46e-05 12635 32504 all phecode
429.1 Heart transplant/surgery Circulatory System 1.07 1.01 – 1.14 0.0236 1219 11696 all phecode
429.2 Abnormal function study of cardiovascular system Circulatory System 1.07 1.04 – 1.1 3.42e-06 6322 29232 all phecode
429.3 Symptoms involving cardiovascular system Circulatory System 1.04 1.02 – 1.06 0.00128 9650 32421 all phecode
429.9 Cardiac complications, not elsewhere classified Circulatory System 1.05 0.971 – 1.14 0.22 723 7072 all phecode
430 Intracranial hemorrhage Circulatory System 1.04 0.961 – 1.12 0.359 789 7842 all phecode
430.1 Subarachnoid hemorrhage Circulatory System 1.15 1.01 – 1.31 0.0337 261 2610 all phecode
430.2 Intracerebral hemorrhage Circulatory System 1.04 0.928 – 1.16 0.523 368 3671 all phecode
430.3 Subdural hemorrhage Circulatory System 0.976 0.857 – 1.11 0.711 272 2680 all phecode
433 Cerebrovascular disease Circulatory System 1.14 1.1 – 1.17 1.15e-16 5463 32242 all phecode
433.1 Occlusion and stenosis of precerebral arteries Circulatory System 1.21 1.15 – 1.27 1.93e-14 1978 16212 all phecode
433.11
Occlusion of cerebral arteries, with cerebral
Occlusion of cerebral arteries, with cerebral infarction
 Circulatory System 1.23 1.08 – 1.4 0.00241 260 2517 all phecode
433.12 Cerebral atherosclerosis Circulatory System 0.992 0.779 – 1.26 0.945 80 789 all phecode
433.2 Occlusion of cerebral arteries Circulatory System 1.13 1.08 – 1.18 5.84e-08 2437 21732 all phecode
433.21
Cerebral artery occlusion, with cerebral
Cerebral artery occlusion, with cerebral infarction
 Circulatory System 1.13 1.08 – 1.18 6.41e-08 2357 21103 all phecode
433.3 Cerebral ischemia Circulatory System 1.1 1.06 – 1.15 1.82e-06 2780 22868 all phecode
433.31 Transient cerebral ischemia Circulatory System 1.1 1.05 – 1.15 1.82e-05 2409 20762 all phecode
433.5 Cerebral aneurysm Circulatory System 1.16 1.06 – 1.28 0.0023 474 4724 all phecode
433.6 Acute, but ill-defined cerebrovascular disease Circulatory System 1.16 1.05 – 1.28 0.00345 464 4518 all phecode
433.8 Late effects of cerebrovascular disease Circulatory System 1.17 1.08 – 1.27 0.000136 695 6822 all phecode
440 Atherosclerosis Circulatory System 1.13 1.09 – 1.18 1.28e-08 2477 19724 all phecode
440.1 Atherosclerosis of renal artery Circulatory System 1.48 1.29 – 1.7 2.11e-08 231 2291 all phecode
440.2 Atherosclerosis of the extremities Circulatory System 1.15 1.09 – 1.22 3.11e-07 1516 13532 all phecode
440.21
Atherosclerosis of native arteries of the
Atherosclerosis of native arteries of the extremities with ulceration or gangrene
 Circulatory System 1.21 1.07 – 1.38 0.00263 274 2669 all phecode
440.22
Atherosclerosis of native arteries of the
Atherosclerosis of native arteries of the extremities with intermittent claudication
 Circulatory System 1.14 1.07 – 1.22 8.3e-05 1040 9647 all phecode
440.9 Atherosclerosis of aorta Circulatory System 1.13 1.05 – 1.22 0.00068 846 8124 all phecode
441 Vascular insufficiency of intestine Circulatory System 1.19 1.08 – 1.3 0.000307 515 5115 all phecode
441.1 Acute vascular insufficiency of intestine Circulatory System 1.21 1.05 – 1.38 0.00716 240 2387 all phecode
441.2 Chronic vascular insufficiency of intestine Circulatory System 1.34 1.13 – 1.58 0.000665 154 1536 all phecode
442 Other aneurysm Circulatory System 1.02 0.976 – 1.06 0.432 2779 21466 all phecode
442.1 Aortic aneurysm Circulatory System 0.971 0.926 – 1.02 0.215 2054 16492 all phecode
442.11 Abdominal aortic aneurysm Circulatory System 0.974 0.916 – 1.04 0.396 1189 10558 all phecode
442.2 Aneurysm of iliac artery Circulatory System 1.06 0.911 – 1.23 0.454 202 2002 all phecode
442.3 Aneurysm of artery of lower extremity Circulatory System 1.14 0.966 – 1.34 0.122 179 1765 all phecode
442.4 Arterial dissection Circulatory System 1.11 0.95 – 1.29 0.195 184 1840 all phecode
442.8 Aneurysm of other specified artery Circulatory System 1.05 0.941 – 1.16 0.408 399 3978 all phecode
443 Peripheral vascular disease Circulatory System 1.12 1.08 – 1.16 8.26e-09 3086 24814 all phecode
443.1 Raynaud's syndrome Circulatory System 0.966 0.894 – 1.04 0.38 742 7390 all phecode
443.7
Peripheral angiopathy in diseases classified
Peripheral angiopathy in diseases classified elsewhere
 Circulatory System 1.18 1.03 – 1.36 0.0178 220 2087 all phecode
443.8 Other specified peripheral vascular diseases Circulatory System 1.14 1.09 – 1.19 8.08e-10 2557 21985 all phecode
443.9 Peripheral vascular disease, unspecified Circulatory System 1.17 1.12 – 1.22 4.74e-12 2341 18862 all phecode
444 Arterial embolism and thrombosis Circulatory System 1.11 1.04 – 1.2 0.00352 848 8423 all phecode
444.1
Arterial embolism and thrombosis of lower
Arterial embolism and thrombosis of lower extremity artery
 Circulatory System 1.14 1.01 – 1.29 0.0277 313 3099 all phecode
444.2 Embolism and thrombosis of abdominal aorta Circulatory System 1.25 1.05 – 1.48 0.0113 155 1548 all phecode
446 Polyarteritis nodosa and allied conditions Circulatory System 1.08 0.981 – 1.19 0.115 460 4559 all phecode
446.4 Wegener's granulomatosis Circulatory System 1.02 0.841 – 1.25 0.814 109 1075 all phecode
446.5 Giant cell arteritis Circulatory System 1.08 0.859 – 1.37 0.496 79 749 all phecode
446.9 Arteritis NOS Circulatory System 1.08 0.959 – 1.22 0.199 289 2876 all phecode
447 Other disorders of arteries and arterioles Circulatory System 1.1 1.05 – 1.14 9.4e-06 2647 22765 all phecode
447.1 Stricture of artery Circulatory System 1.14 1.03 – 1.25 0.0072 523 5163 all phecode
447.7 Aortic ectasia Circulatory System 1.02 0.945 – 1.1 0.641 804 7938 all phecode
448 Disease of capillaries Circulatory System 0.931 0.876 – 0.989 0.0199 1237 12127 all phecode
450 Noninfectious disorders of lymphatic channels Circulatory System 1.02 0.973 – 1.07 0.417 2104 20985 all phecode
451 Phlebitis and thrombophlebitis Circulatory System 0.999 0.925 – 1.08 0.982 738 7355 all phecode
451.2
Phlebitis and thrombophlebitis of lower
Phlebitis and thrombophlebitis of lower extremities
 Circulatory System 1.01 0.885 – 1.16 0.858 244 2437 all phecode
452 Other venous embolism and thrombosis Circulatory System 0.994 0.964 – 1.03 0.726 4957 29867 all phecode
452.1 Iatrogenic pulmonary embolism and infarction Circulatory System 0.903 0.794 – 1.03 0.121 276 2747 all phecode
452.2 Deep vein thrombosis [DVT] Circulatory System 0.996 0.959 – 1.03 0.823 3260 26940 all phecode
452.8 Postphlebitic syndrome Circulatory System 0.902 0.764 – 1.07 0.226 154 1529 all phecode
453 Chronic venous hypertension Circulatory System 0.969 0.839 – 1.12 0.664 220 2168 all phecode
454 Varicose veins Circulatory System 0.98 0.942 – 1.02 0.333 2827 24555 all phecode
454.1 Varicose veins of lower extremity Circulatory System 0.981 0.94 – 1.02 0.375 2469 21426 all phecode
454.11 Varicose veins of lower extremity, symptomtic Circulatory System 0.977 0.927 – 1.03 0.396 1565 15056 all phecode
455 Hemorrhoids Circulatory System 0.951 0.924 – 0.98 0.000844 5799 29818 all phecode
456 Chronic venous insufficiency [CVI] Circulatory System 0.988 0.951 – 1.03 0.544 3097 24898 all phecode
457
Encounter for long-term (current) use of
Encounter for long-term (current) use of anticoagulants, antithrombotics, aspirin
 Circulatory System 1.12 1.07 – 1.18 1.91e-06 2095 15309 all phecode
457.2
Encounter for long-term (current) use of
Encounter for long-term (current) use of antiplatelets/antithrombotics
 Circulatory System 1.24 1.1 – 1.4 0.000371 324 3221 all phecode
457.3 Encounter for long-term (current) use of aspirin Circulatory System 1.13 1.07 – 1.18 1.29e-06 1973 14689 all phecode
458 Hypotension Circulatory System 0.988 0.958 – 1.02 0.44 5091 32185 all phecode
458.1 Orthostatic hypotension Circulatory System 0.971 0.917 – 1.03 0.329 1344 12938 all phecode
458.2 Iatrogenic hypotension Circulatory System 1.02 0.954 – 1.08 0.621 1109 11012 all phecode
458.9 Hypotension NOS Circulatory System 0.985 0.954 – 1.02 0.35 4618 31186 all phecode
459 Other disorders of circulatory system Circulatory System 1.03 1.01 – 1.06 0.00992 7825 34792 all phecode
459.1 Hemorrhage NOS Circulatory System 0.991 0.921 – 1.07 0.801 834 8215 all phecode
459.7 Blood vessel replaced Circulatory System 1.03 0.97 – 1.09 0.358 1305 13023 all phecode
459.9 Circulatory disease NEC Circulatory System 1.04 1.01 – 1.06 0.0139 6706 33592 all phecode
464 Acute sinusitis Respiratory 0.99 0.959 – 1.02 0.522 4792 32137 all phecode
465
Acute upper respiratory infections of multiple
Acute upper respiratory infections of multiple or unspecified sites
 Respiratory 0.965 0.942 – 0.987 0.0026 9601 35915 all phecode
465.2 Acute pharyngitis Respiratory 0.961 0.933 – 0.991 0.0107 5310 32365 all phecode
465.4 Acute laryngitis and tracheitis Respiratory 1.03 0.936 – 1.14 0.519 443 4428 all phecode
470 Septal Deviations/Turbinate Hypertrophy Respiratory 0.928 0.883 – 0.975 0.00328 1797 17640 all phecode
471 Nasal polyps Respiratory 0.938 0.861 – 1.02 0.147 592 5881 all phecode
472 Chronic pharyngitis and nasopharyngitis Respiratory 0.956 0.91 – 1 0.0734 1797 16986 all phecode
473 Diseases of the larynx and vocal cords Respiratory 0.987 0.95 – 1.03 0.516 2983 25244 all phecode
473.1 Chronic laryngitis Respiratory 0.881 0.688 – 1.13 0.318 68 674 all phecode
473.3 Paralysis/spasm of vocal cords or larynx Respiratory 0.934 0.86 – 1.02 0.111 628 6254 all phecode
473.4 Voice disturbance Respiratory 0.992 0.95 – 1.04 0.73 2336 21975 all phecode
474 Acute and chronic tonsillitis Respiratory 0.937 0.872 – 1.01 0.0803 880 7892 all phecode
474.1 Acute tonsillitis Respiratory 0.896 0.796 – 1.01 0.0674 335 3181 all phecode
474.2 Chronic tonsillitis and adenoiditis Respiratory 0.936 0.863 – 1.01 0.108 700 6445 all phecode
475 Chronic sinusitis Respiratory 0.958 0.928 – 0.99 0.0112 4378 27891 all phecode
475.9 Postnasal drip Respiratory 0.892 0.833 – 0.956 0.00116 922 9017 all phecode
476 Allergic rhinitis Respiratory 0.984 0.963 – 1.01 0.158 12687 28117 all phecode
477 Epistaxis or throat hemorrhage Respiratory 1.03 0.966 – 1.09 0.389 1150 11318 all phecode
478 Throat pain Respiratory 0.915 0.824 – 1.02 0.0933 426 4195 all phecode
479 Other upper respiratory disease Respiratory 0.983 0.954 – 1.01 0.24 5627 28048 all phecode
480 Pneumonia Respiratory 1.03 1 – 1.06 0.0303 5947 37034 all phecode
480.1 Bacterial pneumonia Respiratory 1.06 0.992 – 1.12 0.0889 1155 11495 all phecode
480.11 Pneumococcal pneumonia Respiratory 1 0.917 – 1.1 0.945 568 5644 all phecode
480.12 Pseudomonal pneumonia Respiratory 1.03 0.866 – 1.22 0.769 153 1523 all phecode
480.13 MRSA pneumonia Respiratory 1.11 0.915 – 1.35 0.292 117 1165 all phecode
480.2 Viral pneumonia Respiratory 1.01 0.877 – 1.17 0.854 202 1992 all phecode
480.3 Pneumonia due to fungus (mycoses) Respiratory 1.05 0.891 – 1.24 0.562 159 1590 all phecode
480.5 Bronchopneumonia and lung abscess Respiratory 0.874 0.725 – 1.05 0.154 135 1312 all phecode
481 Influenza Respiratory 0.976 0.922 – 1.03 0.415 1355 13284 all phecode
483 Acute bronchitis and bronchiolitis Respiratory 0.993 0.957 – 1.03 0.688 3412 29871 all phecode
495 Asthma Respiratory 1.04 1.01 – 1.06 0.0025 8671 33569 all phecode
495.1 Chronic obstructive asthma Respiratory 1.05 0.943 – 1.16 0.388 397 3925 all phecode
495.11 Chronic obstructive asthma with exacerbation Respiratory 0.932 0.746 – 1.17 0.538 81 802 all phecode
495.2 Asthma with exacerbation Respiratory 1 0.95 – 1.06 0.956 1629 16033 all phecode
496 Chronic airway obstruction Respiratory 1.06 1.02 – 1.09 0.000527 5343 28343 all phecode
496.1 Emphysema Respiratory 1.05 1.01 – 1.1 0.0245 2134 19414 all phecode
496.2 Chronic bronchitis Respiratory 1.07 1.03 – 1.11 0.000119 4128 26624 all phecode
496.21 Obstructive chronic bronchitis Respiratory 1.07 1.03 – 1.11 0.000263 3747 25467 all phecode
496.3 Bronchiectasis Respiratory 0.999 0.912 – 1.09 0.982 549 5453 all phecode
497 Bronchitis Respiratory 0.987 0.941 – 1.04 0.591 1946 18824 all phecode
498 Acute bronchospasm Respiratory 1.05 0.952 – 1.15 0.352 496 4943 all phecode
499 Cystic fibrosis Respiratory 0.913 0.77 – 1.08 0.296 151 1510 all phecode
500 Lung disease due to external agents Respiratory 1.03 0.941 – 1.12 0.537 557 5551 all phecode
500.1 Extrinsic allergic alveolitis Respiratory 0.944 0.762 – 1.17 0.601 92 920 all phecode
500.2 Pneumoconiosis Respiratory 1.29 1.03 – 1.63 0.0292 78 764 all phecode
501 Pneumonitis due to inhalation of food or vomitus Respiratory 1.1 1.01 – 1.2 0.0236 634 6225 all phecode
502 Postinflammatory pulmonary fibrosis Respiratory 0.996 0.925 – 1.07 0.911 815 8076 all phecode
503 Pulmonary congestion and hypostasis Respiratory 1.14 1.06 – 1.23 0.00037 835 8243 all phecode
504 Other alveolar and parietoalveolar pneumonopathy Respiratory 1.03 0.944 – 1.12 0.503 595 5878 all phecode
504.1 Idiopathic fibrosing alveolitis Respiratory 0.946 0.839 – 1.07 0.357 311 3084 all phecode
505 Other pulmonary inflamation or edema Respiratory 1.11 1.05 – 1.16 0.00017 1638 15749 all phecode
506 Empyema and pneumothorax Respiratory 1.06 1.02 – 1.1 0.00282 2894 25235 all phecode
507 Pleurisy; pleural effusion Respiratory 1.04 1 – 1.08 0.0369 2916 26208 all phecode
508
Pulmonary collapse; interstitial and
Pulmonary collapse; interstitial and compensatory emphysema
 Respiratory 1.03 0.982 – 1.07 0.253 2382 22588 all phecode
509 Respiratory failure, insufficiency, arrest Respiratory 1.06 1.02 – 1.1 0.000819 4032 29477 all phecode
509.1 Respiratory failure Respiratory 1.11 1.06 – 1.17 1.56e-05 1937 18949 all phecode
509.2 Respiratory insufficiency Respiratory 1.1 1.04 – 1.17 0.00163 1174 11679 all phecode
509.3
Pulmonary insufficiency or respiratory failure
Pulmonary insufficiency or respiratory failure following trauma and surgery
 Respiratory 1.03 0.982 – 1.09 0.202 1689 16489 all phecode
509.8
Dependence on respirator [Ventilator] or
Dependence on respirator [Ventilator] or supplemental oxygen
 Respiratory 1.08 1.03 – 1.14 0.00281 1741 17249 all phecode
510 Other diseases of lung Respiratory 1 0.974 – 1.03 0.849 5503 35907 all phecode
510.2 Lung transplant Respiratory 1.01 0.863 – 1.18 0.898 176 1757 all phecode
512 Other symptoms of respiratory system Respiratory 0.996 0.977 – 1.02 0.684 18621 28154 all phecode
512.1 Wheezing Respiratory 0.983 0.929 – 1.04 0.541 1409 13516 all phecode
512.2 Painful respiration Respiratory 0.988 0.946 – 1.03 0.6 2309 21263 all phecode
512.3 Abnormal chest sounds Respiratory 0.986 0.873 – 1.11 0.814 291 2845 all phecode
512.7 Shortness of breath Respiratory 1.02 0.993 – 1.04 0.173 10034 28081 all phecode
512.8 Cough Respiratory 0.985 0.961 – 1.01 0.212 9501 28148 all phecode
512.9 Other dyspnea Respiratory 1.01 0.983 – 1.03 0.62 10804 28104 all phecode
513 Respiratory abnormalities Respiratory 1.01 0.988 – 1.03 0.379 12932 33822 all phecode
513.3 Hypoventilation Respiratory 1.07 1 – 1.15 0.0497 880 8646 all phecode
513.31 Apnea Respiratory 1.04 0.942 – 1.15 0.448 462 4607 all phecode
513.32 Orthopnea Respiratory 1.08 0.941 – 1.25 0.265 220 2160 all phecode
513.4 Hyperventilation Respiratory 1.04 0.95 – 1.14 0.378 515 5124 all phecode
513.8 Disorders of diaphragm Respiratory 0.947 0.828 – 1.08 0.425 258 2557 all phecode
514 Abnormal findings examination of lungs Respiratory 1.02 0.993 – 1.05 0.136 5365 34834 all phecode
514.1
Abnormal results of function study of pulmonary
Abnormal results of function study of pulmonary system
 Respiratory 1.1 0.966 – 1.25 0.15 258 2580 all phecode
514.2 Solitary pulmonary nodule Respiratory 1.02 0.978 – 1.06 0.418 3018 27338 all phecode
516 Abnormal sputum Respiratory 0.996 0.922 – 1.08 0.922 735 7332 all phecode
516.1 Hemoptysis Respiratory 0.968 0.889 – 1.05 0.451 611 6080 all phecode
519
Other diseases of respiratory system, not
Other diseases of respiratory system, not elsewhere classified
 Respiratory 1.03 1.01 – 1.06 0.0145 6458 39057 all phecode
519.1 Tracheostomy complications Respiratory 1.06 0.921 – 1.23 0.399 214 2136 all phecode
519.2 Respiratory complications Respiratory 0.993 0.898 – 1.1 0.896 445 4430 all phecode
519.8 Other diseases of respiratory system, NEC Respiratory 0.986 0.936 – 1.04 0.614 1588 15787 all phecode
519.9
Symptoms involving respiratory system and other
Symptoms involving respiratory system and other chest symptoms
 Respiratory 1.05 1.02 – 1.08 0.00322 4706 34489 all phecode
520 Disorders of tooth development Digestive 0.981 0.879 – 1.1 0.739 369 3690 all phecode
520.1 Hereditary disturbances in tooth structure Digestive 0.986 0.836 – 1.16 0.864 165 1642 all phecode
520.2 Disturbances in tooth eruption Digestive 0.967 0.839 – 1.11 0.639 218 2172 all phecode
521 Diseases of hard tissues of teeth Digestive 1.11 1.03 – 1.19 0.00438 898 8954 all phecode
521.1 Dental caries Digestive 1.11 1.03 – 1.19 0.0055 837 8349 all phecode
521.2 Dental abrasion, erosion and attrition Digestive 0.984 0.735 – 1.32 0.911 52 510 all phecode
522 Diseases of pulp and periapical tissues Digestive 0.998 0.911 – 1.09 0.971 535 5340 all phecode
522.5 Periapical abscess Digestive 0.987 0.895 – 1.09 0.796 459 4583 all phecode
523 Gingival and periodontal diseases Digestive 1.01 0.931 – 1.09 0.847 718 7180 all phecode
523.1 Gingivitis Digestive 1.08 0.905 – 1.29 0.4 142 1418 all phecode
523.3 Periodontitis (acute or chronic) Digestive 1.02 0.913 – 1.14 0.716 364 3636 all phecode
523.31 Acute periodontitis Digestive 1.04 0.926 – 1.18 0.482 311 3109 all phecode
523.32 Chronic periodontitis Digestive 1.08 0.899 – 1.31 0.396 122 1204 all phecode
524 Dentofacial anomalies, including malocclusion Digestive 0.897 0.803 – 1 0.0536 363 3630 all phecode
524.3 Anomalies of tooth position/malocclusion Digestive 0.911 0.789 – 1.05 0.208 220 2200 all phecode
525
Other diseases of the teeth and supporting
Other diseases of the teeth and supporting structures
 Digestive 1.02 0.951 – 1.08 0.656 1039 10382 all phecode
525.1 Loss of teeth or edentulism Digestive 0.977 0.876 – 1.09 0.683 374 3731 all phecode
526 Diseases of the jaws Digestive 0.952 0.914 – 0.991 0.0176 2680 26455 all phecode
526.1 Cysts of the jaws Digestive 1.05 0.918 – 1.2 0.493 247 2470 all phecode
526.3 Anomalies of jaw size/symmetry Digestive 0.815 0.709 – 0.938 0.00417 241 2383 all phecode
526.4 Temporomandibular joint disorders Digestive 0.93 0.881 – 0.982 0.00935 1504 15025 all phecode
526.41 Temporomandibular joint disorder, unspecified Digestive 0.956 0.899 – 1.02 0.154 1187 11858 all phecode
526.42 Arthralgia/ankylosis of temporomandibular joint Digestive 0.912 0.844 – 0.985 0.0193 741 7400 all phecode
526.5 Inflammatory conditions of jaw Digestive 1.01 0.891 – 1.14 0.889 287 2864 all phecode
526.8 Exostosis of jaw Digestive 0.918 0.696 – 1.21 0.541 53 521 all phecode
526.9 Jaw disease NOS Digestive 0.99 0.899 – 1.09 0.83 487 4867 all phecode
527 Diseases of the salivary glands Digestive 1.01 0.963 – 1.06 0.633 1781 17771 all phecode
527.1 Hypertrophy of salivary gland Digestive 1.14 0.879 – 1.47 0.33 58 579 all phecode
527.2 Sialoadenitis Digestive 1.01 0.908 – 1.12 0.847 394 3936 all phecode
527.7 Disturbance of salivary secretion Digestive 0.938 0.876 – 1 0.0672 952 9481 all phecode
527.8 Other specified diseases of the salivary glands Digestive 1.16 1.02 – 1.32 0.0274 254 2540 all phecode
528
Diseases of the oral soft tissues, excluding
Diseases of the oral soft tissues, excluding lesions specific for gingiva and tongue
 Digestive 1 0.961 – 1.04 0.95 2643 26197 all phecode
528.1 Stomatitis and mucositis Digestive 0.955 0.881 – 1.04 0.271 668 6657 all phecode
528.11 Stomatitis and mucositis (ulcerative) Digestive 1.05 0.907 – 1.21 0.537 211 2110 all phecode
528.12 Oral aphthae Digestive 0.907 0.785 – 1.05 0.185 215 2137 all phecode
528.3 Cellulitis and abscess of oral soft tissues Digestive 1.05 0.919 – 1.21 0.446 235 2338 all phecode
528.4 Cysts of oral soft tissues Digestive 1.21 0.996 – 1.48 0.055 124 1229 all phecode
528.41 Cyst of the salivary gland Digestive 1.12 0.87 – 1.44 0.379 77 760 all phecode
528.5 Diseases of lips Digestive 1.01 0.913 – 1.11 0.889 462 4602 all phecode
528.6 Leukoplakia of oral mucosa Digestive 1.1 0.925 – 1.31 0.277 137 1370 all phecode
528.7 Sialolithiasis Digestive 1.03 0.872 – 1.21 0.733 163 1623 all phecode
529 Diseases and other conditions of the tongue Digestive 0.959 0.885 – 1.04 0.309 690 6878 all phecode
529.1 Glossitis Digestive 0.854 0.708 – 1.03 0.0969 129 1281 all phecode
529.6 Glossodynia Digestive 0.909 0.774 – 1.07 0.244 168 1652 all phecode
530 Diseases of esophagus Digestive 1 0.981 – 1.02 0.909 17081 27931 all phecode
530.1 Esophagitis, GERD and related diseases Digestive 1 0.983 – 1.02 0.744 16572 27931 all phecode
530.11 GERD Digestive 1 0.984 – 1.02 0.721 16143 27929 all phecode
530.12 Ulcer of esophagus Digestive 1.05 0.944 – 1.16 0.378 400 3983 all phecode
530.13 Barrett's esophagus Digestive 0.951 0.881 – 1.03 0.193 762 7584 all phecode
530.14 Reflux esophagitis Digestive 0.979 0.933 – 1.03 0.4 1900 17495 all phecode
530.15 Eosinophilic esophagitis Digestive 0.845 0.734 – 0.973 0.0192 221 2210 all phecode
530.2 Esophageal bleeding (varices/hemorrhage) Digestive 0.969 0.892 – 1.05 0.453 651 6473 all phecode
530.3 Stricture and stenosis of esophagus Digestive 0.968 0.903 – 1.04 0.355 911 8971 all phecode
530.5 Disorders of esophageal motility Digestive 0.983 0.897 – 1.08 0.71 548 5432 all phecode
530.6 Diverticulum of esophagus, acquired Digestive 0.736 0.611 – 0.886 0.00122 129 1265 all phecode
530.7 Gastroesophageal laceration-hemorrhage syndrome Digestive 1.12 0.885 – 1.41 0.355 82 812 all phecode
530.9 Heartburn Digestive 0.977 0.926 – 1.03 0.402 1519 14928 all phecode
531 Peptic ulcer (excl. esophageal) Digestive 1 0.954 – 1.05 0.991 2073 20617 all phecode
531.1 Hemorrhage from gastrointestinal ulcer Digestive 1.09 0.976 – 1.21 0.132 391 3883 all phecode
531.2 Gastric ulcer Digestive 1 0.941 – 1.06 0.996 1201 11970 all phecode
531.3 Duodenal ulcer Digestive 1.08 0.983 – 1.19 0.108 467 4640 all phecode
531.4 Peptic ulcer, site unspecified Digestive 0.985 0.915 – 1.06 0.687 804 8018 all phecode
531.5 Gastrojejunal ulcer Digestive 1.08 0.916 – 1.28 0.358 150 1500 all phecode
532 Dysphagia Digestive 1.01 0.978 – 1.04 0.596 5585 26852 all phecode
535 Gastritis and duodenitis Digestive 1.01 0.975 – 1.06 0.486 2799 27335 all phecode
535.1 Acute gastritis Digestive 1.06 0.996 – 1.13 0.0649 1178 11750 all phecode
535.2 Atrophic gastritis Digestive 1.03 0.923 – 1.16 0.56 344 3413 all phecode
535.6 Duodenitis Digestive 1.08 0.961 – 1.21 0.204 334 3337 all phecode
535.8 Other specified gastritis Digestive 0.982 0.904 – 1.07 0.664 638 6354 all phecode
535.9 Gastritis and duodenitis, NOS Digestive 0.996 0.939 – 1.06 0.903 1255 12511 all phecode
536 Disorders of function of stomach Digestive 0.982 0.944 – 1.02 0.362 2911 27685 all phecode
536.3 Gastroparesis Digestive 1.02 0.946 – 1.11 0.567 706 6901 all phecode
536.7
Complications of gastrostomy, colostomy and
Complications of gastrostomy, colostomy and enterostomy
 Digestive 0.957 0.863 – 1.06 0.407 407 4059 all phecode
536.8
Dyspepsia and other specified disorders of
Dyspepsia and other specified disorders of function of stomach
 Digestive 0.967 0.925 – 1.01 0.153 2150 21094 all phecode
537 Other disorders of stomach and duodenum Digestive 1.02 0.978 – 1.05 0.422 3183 30048 all phecode
537.1 Lesions of stomach and duodenum Digestive 1.13 0.968 – 1.33 0.12 173 1725 all phecode
539 Bariatric surgery Digestive 1.06 1 – 1.12 0.0326 1509 15074 all phecode
540 Appendiceal conditions Digestive 0.909 0.826 – 1 0.0517 495 4948 all phecode
540.1 Appendicitis Digestive 0.918 0.829 – 1.02 0.104 425 4239 all phecode
540.11 Acute appendicitis Digestive 0.922 0.824 – 1.03 0.16 353 3511 all phecode
550 Abdominal hernia Digestive 0.982 0.956 – 1.01 0.176 6768 37731 all phecode
550.1 Inguinal hernia Digestive 0.92 0.874 – 0.968 0.00136 1744 16488 all phecode
550.2 Diaphragmatic hernia Digestive 0.975 0.937 – 1.01 0.213 2817 25849 all phecode
550.3 Femoral hernia Digestive 0.785 0.659 – 0.935 0.00678 131 1291 all phecode
550.4 Umbilical hernia Digestive 0.973 0.918 – 1.03 0.365 1313 13110 all phecode
550.5 Ventral hernia Digestive 1 0.96 – 1.05 0.858 2241 22163 all phecode
550.6 Incisional hernia Digestive 1 0.943 – 1.06 0.999 1313 13111 all phecode
555
Inflammatory bowel disease and other
Inflammatory bowel disease and other gastroenteritis and colitis
 Digestive 0.949 0.899 – 1 0.0538 1536 15153 all phecode
555.1 Regional enteritis Digestive 0.96 0.897 – 1.03 0.248 919 9095 all phecode
555.2 Ulcerative colitis Digestive 0.926 0.865 – 0.992 0.0275 937 9315 all phecode
555.21 Ulcerative colitis (chronic) Digestive 0.939 0.858 – 1.03 0.175 537 5315 all phecode
556 Ulceration of the lower GI tract Digestive 0.997 0.917 – 1.08 0.943 632 6267 all phecode
556.1 Ulceration of intestine Digestive 1.02 0.931 – 1.11 0.688 551 5451 all phecode
556.11
Angiodysplasia of intestine (without mention of
Angiodysplasia of intestine (without mention of hemorrhage)
 Digestive 1.12 0.969 – 1.29 0.127 214 2093 all phecode
557 Intestinal malabsorption (non-celiac) Digestive 1.02 0.966 – 1.07 0.531 1716 16490 all phecode
557.1 Celiac disease Digestive 0.954 0.862 – 1.06 0.365 421 4026 all phecode
558 Noninfectious gastroenteritis Digestive 1 0.969 – 1.04 0.801 3458 26408 all phecode
559 Ileostomy status Digestive 0.976 0.912 – 1.04 0.48 957 9565 all phecode
560 Intestinal obstruction without mention of hernia Digestive 1.01 0.968 – 1.05 0.767 3004 24851 all phecode
560.1 Paralytic ileus Digestive 1.03 0.981 – 1.09 0.22 1627 15714 all phecode
560.2 Impaction of intestine Digestive 0.972 0.874 – 1.08 0.607 387 3779 all phecode
560.3 Peritoneal or intestinal adhesions Digestive 0.989 0.87 – 1.12 0.864 266 2647 all phecode
560.4 Other intestinal obstruction Digestive 1.02 0.964 – 1.07 0.568 1651 16170 all phecode
561 Symptoms involving digestive system Digestive 0.988 0.948 – 1.03 0.577 2608 21766 all phecode
562 Diverticulosis and diverticulitis Digestive 0.966 0.938 – 0.995 0.0207 6295 23431 all phecode
562.1 Diverticulosis Digestive 0.966 0.938 – 0.995 0.0219 6246 23383 all phecode
562.2 Diverticulitis Digestive 0.987 0.937 – 1.04 0.635 1611 15162 all phecode
564 Functional digestive disorders Digestive 1 0.977 – 1.02 0.966 11411 28676 all phecode
564.1 Irritable Bowel Syndrome Digestive 0.981 0.946 – 1.02 0.32 3457 22266 all phecode
564.9 Personal history of diseases of digestive system Digestive 0.98 0.943 – 1.02 0.298 3074 25861 all phecode
565 Anal and rectal conditions Digestive 0.952 0.918 – 0.988 0.00855 3355 30757 all phecode
565.1 Anal and rectal polyp Digestive 0.949 0.895 – 1.01 0.0829 1305 12649 all phecode
567 Peritonitis and retroperitoneal infections Digestive 1.07 1.01 – 1.13 0.0254 1364 13616 all phecode
568 Other disorders of peritoneum Digestive 1.09 1.04 – 1.15 0.000834 1705 17038 all phecode
568.1
Peritoneal adhesions (postoperative)
Peritoneal adhesions (postoperative) (postinfection)
 Digestive 1.11 1.04 – 1.17 0.000995 1247 12468 all phecode
569 Other disorders of intestine Digestive 0.993 0.968 – 1.02 0.564 8079 35231 all phecode
569.1 Toxic gastroenteritis and colitis Digestive 0.99 0.881 – 1.11 0.871 326 3260 all phecode
569.2 Gastrointestinal complications Digestive 0.981 0.927 – 1.04 0.495 1395 13933 all phecode
571 Chronic liver disease and cirrhosis Digestive 1.05 1.02 – 1.09 0.0012 4610 32562 all phecode
571.5 Other chronic nonalcoholic liver disease Digestive 1.05 1.02 – 1.08 0.00394 4342 32234 all phecode
571.51 Cirrhosis of liver without mention of alcohol Digestive 1.07 1.01 – 1.15 0.0341 1018 10095 all phecode
571.6 Primary biliary cirrhosis Digestive 1.04 0.89 – 1.22 0.617 179 1790 all phecode
571.8
Liver abscess and sequelae of chronic liver
Liver abscess and sequelae of chronic liver disease
 Digestive 1.06 0.991 – 1.14 0.0886 950 9498 all phecode
571.81 Portal hypertension Digestive 1.01 0.927 – 1.11 0.786 573 5730 all phecode
572 Ascites (non malignant) Digestive 1.08 1.04 – 1.13 0.000428 2278 22675 all phecode
573 Other disorders of liver Digestive 1.04 1.01 – 1.07 0.00469 5599 33620 all phecode
573.1 Chronic passive congestion of liver Digestive 1.18 0.992 – 1.4 0.0615 136 1359 all phecode
573.2 Liver replaced by transplant Digestive 1.02 0.899 – 1.15 0.789 292 2920 all phecode
573.3 Hepatomegaly Digestive 1.17 1.06 – 1.29 0.00222 470 4700 all phecode
573.4 Acute and subacute necrosis of liver Digestive 1.2 1.07 – 1.36 0.00243 316 3149 all phecode
573.5 Jaundice (not of newborn) Digestive 0.989 0.924 – 1.06 0.752 958 9496 all phecode
573.6
Nonspecific elevation of levels of transaminase
Nonspecific elevation of levels of transaminase or lactic acid dehydrogenase [LDH]
 Digestive 1.01 0.973 – 1.05 0.539 2756 26470 all phecode
573.7 Abnormal results of function study of liver Digestive 1.02 0.979 – 1.06 0.367 3018 27774 all phecode
573.9 Abnormal serum enzyme levels Digestive 1.03 0.995 – 1.06 0.0996 4679 33866 all phecode
574 Cholelithiasis and cholecystitis Digestive 1.03 0.997 – 1.07 0.0749 3177 30809 all phecode
574.1 Cholelithiasis Digestive 1.03 0.99 – 1.07 0.14 2924 28874 all phecode
574.11 Cholelithiasis with acute cholecystitis Digestive 0.963 0.861 – 1.08 0.509 342 3412 all phecode
574.12 Cholelithiasis with other cholecystitis Digestive 1.03 0.939 – 1.12 0.574 553 5501 all phecode
574.2 Calculus of bile duct Digestive 1.01 0.944 – 1.09 0.704 852 8503 all phecode
574.3 Cholecystitis without cholelithiasis Digestive 0.963 0.895 – 1.04 0.305 822 8181 all phecode
575 Other biliary tract disease Digestive 1.01 0.97 – 1.06 0.53 2266 22555 all phecode
575.1 Cholangitis Digestive 0.952 0.85 – 1.07 0.392 354 3530 all phecode
575.2 Obstruction of bile duct Digestive 0.976 0.897 – 1.06 0.578 621 6201 all phecode
575.6 Cholesterolosis of gallbladder Digestive 0.902 0.781 – 1.04 0.161 207 2063 all phecode
575.7 Other disorders of gallbladder Digestive 1.06 0.986 – 1.13 0.118 939 9382 all phecode
575.8 Other disorders of biliary tract Digestive 0.996 0.936 – 1.06 0.889 1154 11523 all phecode
575.9
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of biliary tract
 Digestive 0.994 0.87 – 1.13 0.925 260 2600 all phecode
577 Diseases of pancreas Digestive 1.04 0.99 – 1.08 0.125 2225 22106 all phecode
577.1 Acute pancreatitis Digestive 1.07 1.01 – 1.14 0.0287 1212 12110 all phecode
577.2 Chronic pancreatitis Digestive 1.08 0.981 – 1.19 0.119 495 4950 all phecode
577.3 Cyst and pseudocyst of pancreas Digestive 1.03 0.946 – 1.13 0.464 570 5601 all phecode
578 Gastrointestinal hemorrhage Digestive 1.02 0.987 – 1.05 0.252 4554 37045 all phecode
578.1 Hematemesis Digestive 1.11 1.01 – 1.22 0.0263 485 4842 all phecode
578.2 Blood in stool Digestive 1.01 0.965 – 1.05 0.808 2743 26554 all phecode
578.8 Hemorrhage of rectum and anus Digestive 0.993 0.95 – 1.04 0.776 2210 21750 all phecode
578.9 Hemorrhage of gastrointestinal tract Digestive 1.09 1.03 – 1.15 0.00143 1562 15345 all phecode
579 Other symptoms involving abdomen and pelvis Digestive 1.03 0.993 – 1.06 0.124 4431 34209 all phecode
579.2 Splenomegaly Digestive 1.08 0.999 – 1.17 0.052 730 7262 all phecode
579.8 Nonspecific abnormal findings in stool contents Digestive 0.993 0.939 – 1.05 0.809 1410 13877 all phecode
580 Nephritis; nephrosis; renal sclerosis Genitourinary 1.14 1.09 – 1.2 1.11e-07 1881 15516 all phecode
580.1 Glomerulonephritis Genitourinary 1.22 1.09 – 1.35 0.000374 401 3992 all phecode
580.11 Proliferative glomerulonephritis Genitourinary 1.1 0.923 – 1.31 0.29 146 1440 all phecode
580.12 Non-proliferative glomerulonephritis Genitourinary 1.26 1.04 – 1.54 0.0209 114 1128 all phecode
580.13 Acute glomerulonephritis, NOS Genitourinary 1.01 0.764 – 1.33 0.951 61 600 all phecode
580.14 Chronic glomerulonephritis, NOS Genitourinary 1.23 1.08 – 1.4 0.00193 277 2760 all phecode
580.2
Nephrotic syndrome without mention of
Nephrotic syndrome without mention of glomerulonephritis
 Genitourinary 1.18 1.02 – 1.36 0.0217 221 2193 all phecode
580.3
Nephritis and nephropathy without mention of
Nephritis and nephropathy without mention of glomerulonephritis
 Genitourinary 1.15 1.09 – 1.22 9e-07 1502 11930 all phecode
580.31
Nephritis and nephropathy in diseases
Nephritis and nephropathy in diseases classified elsewhere
 Genitourinary 1.22 1.13 – 1.3 5.22e-08 992 7228 all phecode
580.32
Nephritis and nephropathy with pathological
Nephritis and nephropathy with pathological lesion
 Genitourinary 1.1 1.02 – 1.2 0.0194 683 6612 all phecode
580.4 Renal sclerosis, NOS Genitourinary 1.19 1.06 – 1.33 0.00231 340 3400 all phecode
585 Renal failure Genitourinary 1.15 1.12 – 1.18 6.63e-25 7470 32340 all phecode
585.1 Acute renal failure Genitourinary 1.17 1.13 – 1.21 2.15e-20 4265 27230 all phecode
585.2 Renal failure NOS Genitourinary 1.15 1.07 – 1.24 0.000151 832 8162 all phecode
585.3 Chronic renal failure [CKD] Genitourinary 1.16 1.12 – 1.19 3.41e-21 5580 29470 all phecode
585.31 Renal dialysis Genitourinary 1.17 1.08 – 1.26 9.39e-05 747 7423 all phecode
585.32 End stage renal disease Genitourinary 1.19 1.11 – 1.27 4.04e-07 1007 9783 all phecode
585.33 Chronic Kidney Disease, Stage III Genitourinary 1.19 1.14 – 1.23 1.09e-17 3209 21312 all phecode
585.34 Chronic Kidney Disease, Stage IV Genitourinary 1.21 1.13 – 1.29 3.99e-08 977 9190 all phecode
585.4 Chronic kidney disease, Stage I or II Genitourinary 1.19 1.12 – 1.27 1.39e-08 1227 11191 all phecode
586 Other disorders of the kidney and ureters Genitourinary 1.08 1.06 – 1.11 1.42e-09 7628 34189 all phecode
586.1 Anatomical abnormatilies of kidney and ureters Genitourinary 1.08 0.972 – 1.21 0.146 349 3480 all phecode
586.11 Small kidney Genitourinary 1.13 0.983 – 1.31 0.0839 210 2093 all phecode
586.12 Vesicoureteral reflux Genitourinary 1.02 0.853 – 1.22 0.841 136 1360 all phecode
586.2 Cyst of kidney, acquired Genitourinary 1.03 0.972 – 1.09 0.33 1381 12912 all phecode
586.3 Vascular disorders of kidney/hypertrophy Genitourinary 0.956 0.821 – 1.11 0.558 187 1862 all phecode
586.4 Stricture/obstruction of ureter Genitourinary 1.03 0.98 – 1.08 0.251 1821 17115 all phecode
587 Kidney replaced by transpant Genitourinary 1.12 1.04 – 1.2 0.00331 819 8134 all phecode
588 Disorders resulting from impaired renal function Genitourinary 1.18 1.1 – 1.26 1.8e-06 976 9389 all phecode
588.1 Renal osteodystrophy Genitourinary 1.14 1.01 – 1.29 0.0318 290 2900 all phecode
588.2 Secondary hyperparathyroidism (of renal origin) Genitourinary 1.16 1.07 – 1.25 0.000208 755 7275 all phecode
589 Abnormal results of function study of kidney Genitourinary 1.13 1.06 – 1.21 0.000226 1007 9834 all phecode
590 Pyelonephritis Genitourinary 1.01 0.955 – 1.07 0.738 1461 14350 all phecode
591 Urinary tract infection Genitourinary 0.998 0.975 – 1.02 0.883 9873 32513 all phecode
592 Cystitis and urethritis Genitourinary 0.984 0.946 – 1.02 0.413 3038 24207 all phecode
592.1 Cystitis Genitourinary 0.984 0.945 – 1.02 0.424 2880 23279 all phecode
592.11 Acute cystitis Genitourinary 0.986 0.938 – 1.04 0.588 1783 16452 all phecode
592.12 Chronic cystitis Genitourinary 0.894 0.78 – 1.02 0.108 239 2343 all phecode
592.13 Chronic interstitial cystitis Genitourinary 0.937 0.847 – 1.04 0.209 431 4310 all phecode
592.2 Urethritis and urethral syndrome Genitourinary 1.08 0.932 – 1.24 0.32 210 2093 all phecode
593 Hematuria Genitourinary 1.02 0.987 – 1.05 0.256 4859 32063 all phecode
593.1 Gross hematuria Genitourinary 1.02 0.965 – 1.07 0.504 1585 14824 all phecode
593.2 Microscopic hematuria Genitourinary 1.04 0.976 – 1.11 0.215 1049 10301 all phecode
594 Urinary calculus Genitourinary 1.03 1.01 – 1.06 0.0199 6707 38209 all phecode
594.1 Calculus of kidney Genitourinary 1.03 1.01 – 1.06 0.0158 6273 38051 all phecode
594.2 Calculus of lower urinary tract Genitourinary 0.829 0.743 – 0.924 0.000724 366 3638 all phecode
594.3 Calculus of ureter Genitourinary 0.991 0.936 – 1.05 0.763 1361 13561 all phecode
594.8 Renal colic Genitourinary 1.05 0.942 – 1.18 0.365 356 3560 all phecode
595 Hydronephrosis Genitourinary 1.03 0.98 – 1.09 0.233 1670 16658 all phecode
596 Other disorders of bladder Genitourinary 0.998 0.961 – 1.04 0.926 3074 28020 all phecode
596.1 Bladder neck obstruction Genitourinary 0.923 0.83 – 1.03 0.139 400 3942 all phecode
596.5 Functional disorders of bladder Genitourinary 1.01 0.964 – 1.07 0.584 1719 17049 all phecode
597 Other disorders of urethra and urinary tract Genitourinary 0.998 0.939 – 1.06 0.96 1211 11998 all phecode
597.1 Urethral stricture (not specified as infectious) Genitourinary 1.01 0.934 – 1.1 0.747 661 6537 all phecode
597.2 Urinary complications NEC Genitourinary 1.05 0.983 – 1.12 0.148 1049 10479 all phecode
597.8 Urethral hypermobility/ISD Genitourinary 0.958 0.819 – 1.12 0.592 189 1873 all phecode
598 Abnormal findings on examination of urine Genitourinary 0.935 0.779 – 1.12 0.473 138 1356 all phecode
598.4 Other cells and casts in urine Genitourinary 0.956 0.786 – 1.16 0.649 122 1192 all phecode
599 Other symptoms/disorders or the urinary system Genitourinary 0.992 0.972 – 1.01 0.457 14168 30681 all phecode
599.1 Urinary obstruction Genitourinary 0.907 0.838 – 0.982 0.0159 728 6861 all phecode
599.2 Retention of urine Genitourinary 0.973 0.943 – 1 0.0873 5034 28305 all phecode
599.3 Dysuria Genitourinary 1 0.968 – 1.03 0.982 4397 27849 all phecode
599.4 Urinary incontinence Genitourinary 0.978 0.949 – 1.01 0.155 5599 26960 all phecode
599.5 Frequency of urination and polyuria Genitourinary 0.981 0.951 – 1.01 0.201 5498 28723 all phecode
599.6 Oliguria and anuria Genitourinary 1.02 0.933 – 1.11 0.694 599 5902 all phecode
599.7 Urethral discharge Genitourinary 0.883 0.732 – 1.07 0.197 118 1175 all phecode
599.8 Other symptoms involving urinary system Genitourinary 0.99 0.961 – 1.02 0.516 5446 27963 all phecode
599.9 Other abnormality of urination Genitourinary 0.98 0.943 – 1.02 0.317 3041 24877 all phecode
600 Hyperplasia of prostate Genitourinary 0.964 0.926 – 1 0.0655 4063 11364 all phecode
601 Inflammatory diseases of prostate Genitourinary 0.948 0.888 – 1.01 0.11 1044 9665 all phecode
601.1 Prostatitis Genitourinary 0.884 0.803 – 0.974 0.0124 477 4596 all phecode
601.11 Acute prostatitis Genitourinary 0.975 0.805 – 1.18 0.795 124 1200 all phecode
601.12 Chronic prostatitis Genitourinary 0.809 0.648 – 1.01 0.0594 95 943 all phecode
601.3 Orchitis and epididymitis Genitourinary 1.01 0.906 – 1.12 0.9 389 3822 all phecode
601.4 Balanoposthitis Genitourinary 0.99 0.819 – 1.2 0.915 127 1224 all phecode
601.8
Other inflammatory disorders of male genital
Other inflammatory disorders of male genital organs
 Genitourinary 1.08 0.912 – 1.27 0.384 161 1591 all phecode
602 Other disorders of prostate Genitourinary 0.97 0.868 – 1.08 0.591 361 3399 all phecode
602.3 Dysplasia of prostate Genitourinary 1.02 0.808 – 1.29 0.855 77 730 all phecode
603 Other disorders of testis Genitourinary 0.936 0.847 – 1.04 0.201 440 4354 all phecode
603.1 Hydrocele Genitourinary 0.943 0.834 – 1.07 0.356 293 2882 all phecode
603.2 Spermatocele Genitourinary 0.816 0.69 – 0.965 0.0177 156 1539 all phecode
604 Disorders of penis Genitourinary 0.945 0.872 – 1.02 0.163 685 6748 all phecode
604.1 Redundant prepuce and phimosis/BXO Genitourinary 1.07 0.898 – 1.26 0.469 155 1540 all phecode
604.3 Peyronie's disease Genitourinary 0.819 0.709 – 0.946 0.00665 215 2132 all phecode
605 Erectile dysfunction [ED] Genitourinary 0.984 0.947 – 1.02 0.4 3776 12700 all phecode
608 Other disorders of male genital organs Genitourinary 1.02 0.965 – 1.07 0.531 1645 13758 all phecode
609 Male infertility and abnormal spermatozoa Genitourinary 0.874 0.788 – 0.969 0.0109 424 4196 all phecode
609.1 Infertility, male Genitourinary 0.876 0.775 – 0.991 0.0355 302 2992 all phecode
609.11 Azoospermia and oligospermia Genitourinary 0.965 0.774 – 1.2 0.754 95 950 all phecode
609.2 Abnormal spermatozoa Genitourinary 0.87 0.736 – 1.03 0.105 154 1519 all phecode
610 Benign mammary dysplasias Genitourinary 0.966 0.931 – 1 0.0702 3683 16548 all phecode
610.1 Cystic mastopathy Genitourinary 0.984 0.933 – 1.04 0.545 1633 14191 all phecode
610.2 Fibroadenosis of breast Genitourinary 1.11 0.857 – 1.43 0.436 60 600 all phecode
610.4 Benign neoplasm of breast Genitourinary 0.969 0.93 – 1.01 0.127 2837 16430 all phecode
610.8 Other specified benign mammary dysplasias Genitourinary 0.976 0.92 – 1.04 0.417 1269 12191 all phecode
611 Abnormal findings on mammogram or breast exam Genitourinary 0.962 0.933 – 0.992 0.0122 6067 18690 all phecode
611.1 Abnormal mammogram Genitourinary 0.968 0.936 – 1 0.0522 4980 16120 all phecode
611.11 Mammographic microcalcification Genitourinary 0.97 0.911 – 1.03 0.344 1122 10394 all phecode
611.3 Lump or mass in breast Genitourinary 0.958 0.923 – 0.995 0.0245 3549 18572 all phecode
612
Breast conditions, congenital or relating to
Breast conditions, congenital or relating to hormones
 Genitourinary 0.94 0.881 – 1 0.0643 1051 10425 all phecode
612.1 Galactorrhea Genitourinary 0.991 0.826 – 1.19 0.922 139 1390 all phecode
612.2 Hypertrophy of breast (Gynecomastia) Genitourinary 0.962 0.893 – 1.04 0.303 800 7962 all phecode
612.3 Congenital anomalies of breast Genitourinary 0.697 0.551 – 0.883 0.00272 83 810 all phecode
613 Other nonmalignant breast conditions Genitourinary 0.973 0.94 – 1.01 0.132 3897 22072 all phecode
613.1 Inflammatory disease of breast Genitourinary 1 0.917 – 1.09 0.998 593 5874 all phecode
613.5 Mastodynia Genitourinary 0.961 0.912 – 1.01 0.127 1675 16203 all phecode
613.7 Other signs and symptoms in breast Genitourinary 0.965 0.899 – 1.04 0.32 883 8754 all phecode
613.8 Other specified disorders of breast Genitourinary 0.944 0.881 – 1.01 0.105 932 9248 all phecode
613.9 Breast disorder NOS Genitourinary 0.994 0.941 – 1.05 0.829 1465 14174 all phecode
614 Inflammatory diseases of female pelvic organs Genitourinary 0.97 0.936 – 1.01 0.1 3715 19647 all phecode
614.1
Pelvic peritoneal adhesions, female
Pelvic peritoneal adhesions, female (postoperative) (postinfection)
 Genitourinary 0.883 0.789 – 0.989 0.0322 337 3370 all phecode
614.3 Pelvic inflammatory disease (PID) Genitourinary 1.05 0.952 – 1.15 0.34 478 4773 all phecode
614.31 Acute inflammatory pelvic disease Genitourinary 1.12 0.898 – 1.39 0.321 94 933 all phecode
614.32 Chronic inflammatory pelvic disease Genitourinary 1.09 0.934 – 1.27 0.279 186 1842 all phecode
614.33 Pelvic inflammatory disease, NOS Genitourinary 1.01 0.885 – 1.16 0.869 246 2460 all phecode
614.4 Inflammatory diseases of uterus, except cervix Genitourinary 1 0.849 – 1.18 0.981 165 1639 all phecode
614.5
Inflammatory disease of cervix, vagina, and
Inflammatory disease of cervix, vagina, and vulva
 Genitourinary 0.969 0.932 – 1.01 0.112 3180 19539 all phecode
614.51 Cervicitis and endocervicitis Genitourinary 1.03 0.905 – 1.17 0.647 264 2640 all phecode
614.52 Vaginitis and vulvovaginitis Genitourinary 0.97 0.931 – 1.01 0.148 2732 18924 all phecode
614.53 Cyst or abscess of Bartholin's gland Genitourinary 0.892 0.741 – 1.07 0.227 132 1311 all phecode
614.54 Abscess or ulceration of vulva Genitourinary 0.981 0.854 – 1.13 0.789 225 2244 all phecode
615 Endometriosis Genitourinary 1 0.948 – 1.05 1 1585 14666 all phecode
618 Genital prolapse Genitourinary 0.965 0.921 – 1.01 0.133 2079 17915 all phecode
618.1 Prolapse of vaginal walls Genitourinary 0.95 0.898 – 1 0.073 1408 13456 all phecode
618.2 Uterine/Uterovaginal prolapse Genitourinary 0.965 0.882 – 1.06 0.434 542 5390 all phecode
618.5 Prolapse of vaginal vault after hysterectomy Genitourinary 0.988 0.878 – 1.11 0.846 317 3162 all phecode
618.6 Vaginal enterocele, congenital or acquired Genitourinary 1.01 0.913 – 1.11 0.868 441 4394 all phecode
619 Noninflammatory female genital disorders Genitourinary 0.978 0.948 – 1.01 0.148 5728 18687 all phecode
619.1
Noninflammatory disorders of ovary, fallopian
Noninflammatory disorders of ovary, fallopian tube, and broad ligament
 Genitourinary 1.04 0.98 – 1.11 0.192 1233 12082 all phecode
619.2 Disorders of uterus, NEC Genitourinary 0.985 0.903 – 1.07 0.735 591 5897 all phecode
619.3 Noninflammatory disorders of cervix Genitourinary 0.962 0.874 – 1.06 0.433 483 4823 all phecode
619.4 Noninflammatory disorders of vagina Genitourinary 0.981 0.94 – 1.02 0.384 2525 18404 all phecode
619.5 Noninflammatory disorders of vulva and perineum Genitourinary 0.971 0.913 – 1.03 0.337 1189 11717 all phecode
620 Dysplasia of female genital organs Genitourinary 1.02 0.917 – 1.13 0.732 395 3950 all phecode
620.1 Dysplasia of cervix Genitourinary 0.929 0.794 – 1.09 0.361 178 1780 all phecode
621 Endometrial hyperplasia Genitourinary 1.14 1.03 – 1.26 0.0108 437 4370 all phecode
622 Polyp of female genital organs Genitourinary 0.955 0.903 – 1.01 0.102 1449 14264 all phecode
622.1 Polyp of corpus uteri Genitourinary 0.964 0.905 – 1.03 0.254 1132 11189 all phecode
622.2 Mucous polyp of cervix Genitourinary 0.995 0.901 – 1.1 0.918 445 4444 all phecode
623 Hypertrophy of female genital organs Genitourinary 0.913 0.849 – 0.982 0.0143 824 8165 all phecode
624 Symptoms involving female genital tract Genitourinary 0.965 0.911 – 1.02 0.23 1348 12518 all phecode
624.1 Dystrophy of female genital tract Genitourinary 0.928 0.802 – 1.07 0.315 216 2155 all phecode
624.2 Atrophy of female genital tract Genitourinary 0.918 0.711 – 1.18 0.509 64 615 all phecode
624.9 stress incontinence, female Genitourinary 0.957 0.912 – 1 0.076 1935 15408 all phecode
625
Pain and other symptoms associated with female
Pain and other symptoms associated with female genital organs
 Genitourinary 0.989 0.959 – 1.02 0.494 5653 17303 all phecode
625.1 Dyspareunia Genitourinary 0.992 0.935 – 1.05 0.803 1267 12474 all phecode
626
Disorders of menstruation and other abnormal
Disorders of menstruation and other abnormal bleeding from female genital tract
 Genitourinary 0.978 0.947 – 1.01 0.163 5940 15585 all phecode
626.1 Irregular menstrual cycle/bleeding Genitourinary 0.988 0.953 – 1.02 0.509 4315 14604 all phecode
626.11 Absent or infrequent menstruation Genitourinary 1.02 0.954 – 1.09 0.566 1062 8531 all phecode
626.12 Excessive or frequent menstruation Genitourinary 0.98 0.934 – 1.03 0.415 2097 11991 all phecode
626.13 Irregular menstrual cycle Genitourinary 1.02 0.969 – 1.07 0.482 1957 12265 all phecode
626.14 Irregular menstrual bleeding Genitourinary 1 0.937 – 1.07 0.928 970 8996 all phecode
626.15 Infertility, female, associated with anovulation Genitourinary 0.98 0.881 – 1.09 0.707 394 3789 all phecode
626.2 Dysmenorrhea Genitourinary 1 0.947 – 1.06 0.888 1373 9857 all phecode
626.4 Premenstrual tension syndromes Genitourinary 0.947 0.844 – 1.06 0.349 336 3308 all phecode
626.8 Infertility, female Genitourinary 0.992 0.921 – 1.07 0.829 817 6741 all phecode
627 Menopausal and postmenopausal disorders Genitourinary 0.957 0.925 – 0.991 0.0131 4560 14557 all phecode
627.1 Postmenopausal bleeding Genitourinary 0.944 0.887 – 1.01 0.0713 1146 10338 all phecode
627.2 Symptomatic menopause Genitourinary 0.939 0.901 – 0.978 0.00223 3017 13763 all phecode
627.21 Symptomatic artificial menopause Genitourinary 0.94 0.794 – 1.11 0.473 152 1514 all phecode
627.22
Need for Hormone replacement therapy
Need for Hormone replacement therapy (postmenopausal)
 Genitourinary 0.896 0.802 – 1 0.0538 356 3513 all phecode
627.3 Postmenopausal atrophic vaginitis Genitourinary 0.961 0.899 – 1.03 0.244 997 9484 all phecode
627.4 Premenopausal menorrhagia Genitourinary 0.958 0.858 – 1.07 0.45 361 3580 all phecode
627.5 Premature menopause and other ovarian failure Genitourinary 1.06 0.938 – 1.19 0.356 309 3082 all phecode
628 Ovarian cyst Genitourinary 1 0.954 – 1.05 0.949 1945 13838 all phecode
634 Miscarriage; stillbirth Pregnancy Complications 0.945 0.878 – 1.02 0.134 826 8047 all phecode
634.1 Missed abortion/Hydatidiform mole Pregnancy Complications 0.923 0.811 – 1.05 0.226 273 2715 all phecode
634.3 Ectopic pregnancy Pregnancy Complications 0.934 0.767 – 1.14 0.496 117 1170 all phecode
635
Hemorrhage during pregnancy; childbirth and
Hemorrhage during pregnancy; childbirth and postpartum
 Pregnancy Complications 0.906 0.828 – 0.991 0.0305 563 5309 all phecode
635.2
Antepartum hemorrhage, abruptio placentae, and
Antepartum hemorrhage, abruptio placentae, and placenta previa
 Pregnancy Complications 0.918 0.823 – 1.02 0.129 370 3629 all phecode
635.3 Placenta previa and abruptio placenta Pregnancy Complications 0.941 0.831 – 1.07 0.337 288 2850 all phecode
636
Early or threatened labor; hemorrhage in early
Early or threatened labor; hemorrhage in early pregnancy
 Pregnancy Complications 0.978 0.915 – 1.05 0.512 1080 7870 all phecode
636.1 Threatened premature labor Pregnancy Complications 1.03 0.927 – 1.15 0.562 380 3799 all phecode
636.2 Early onset of delivery Pregnancy Complications 1.07 0.947 – 1.21 0.274 288 2868 all phecode
636.3 Hemorrhage in early pregnancy Pregnancy Complications 1 0.906 – 1.11 0.969 441 4365 all phecode
636.8 Cervical incompetence Pregnancy Complications 1.06 0.836 – 1.35 0.622 77 770 all phecode
637
Short gestation; low birth weight; and fetal
Short gestation; low birth weight; and fetal growth retardation
 Pregnancy Complications 0.927 0.738 – 1.16 0.513 85 850 all phecode
642
Hypertension complicating pregnancy
Hypertension complicating pregnancy, childbirth, and the puerperium
 Pregnancy Complications 1.2 1.1 – 1.31 4.59e-05 585 5725 all phecode
642.1 Preeclampsia and eclampsia Pregnancy Complications 1.09 0.968 – 1.23 0.153 302 3013 all phecode
643 Excessive vomiting in pregnancy Pregnancy Complications 0.998 0.874 – 1.14 0.981 252 2506 all phecode
643.1 Hyperemesis gravidarum Pregnancy Complications 0.981 0.806 – 1.19 0.852 119 1190 all phecode
644 Anemia during pregnancy Pregnancy Complications 0.962 0.834 – 1.11 0.589 224 2224 all phecode
646 Other complications of pregnancy NEC Pregnancy Complications 1.04 0.962 – 1.11 0.355 855 6531 all phecode
647
Infectious and parasitic complications
Infectious and parasitic complications affecting pregnancy
 Pregnancy Complications 1.09 0.945 – 1.27 0.228 211 2093 all phecode
647.1
Infections of genitourinary tract during
Infections of genitourinary tract during pregnancy
 Pregnancy Complications 1.03 0.889 – 1.18 0.731 222 2213 all phecode
647.3 Major puerperal infection Pregnancy Complications 0.954 0.739 – 1.23 0.717 65 650 all phecode
649
Other conditions or status of the mother
Other conditions or status of the mother complicating pregnancy, childbirth, or the puerperium
 Pregnancy Complications 0.958 0.901 – 1.02 0.175 1275 8010 all phecode
649.1
Diabetes or abnormal glucose tolerance
Diabetes or abnormal glucose tolerance complicating pregnancy
 Pregnancy Complications 1.06 0.976 – 1.15 0.168 649 5687 all phecode
653
Problems associated with amniotic cavity and
Problems associated with amniotic cavity and membranes
 Pregnancy Complications 1 0.92 – 1.1 0.927 587 5463 all phecode
654.1
Abnormality of organs and soft tissues of
Abnormality of organs and soft tissues of pelvis complicating pregnancy, childbirth, or the puerperium
 Pregnancy Complications 1.03 0.889 – 1.2 0.669 207 2055 all phecode
654.2 Rhesus isoimmunization in pregnancy Pregnancy Complications 1.02 0.879 – 1.18 0.815 204 2040 all phecode
655
Known or suspected fetal abnormality affecting
Known or suspected fetal abnormality affecting management of mother
 Pregnancy Complications 0.996 0.943 – 1.05 0.895 1624 10064 all phecode
655.1 Abnormality in fetal heart rate or rhythm Pregnancy Complications 1.01 0.93 – 1.1 0.766 616 5533 all phecode
656 Other perinatal conditions of fetus or newborn Pregnancy Complications 1.02 0.95 – 1.1 0.582 898 7014 all phecode
656.2 Respiratory conditions of fetus and newborn Pregnancy Complications 0.913 0.711 – 1.17 0.477 66 660 all phecode
669 Complications of labor and delivery NEC Pregnancy Complications 1.04 0.964 – 1.11 0.333 887 6802 all phecode
671
Venous/cerebrovascular complications embolism
Venous/cerebrovascular complications embolism in pregnancy and the puerperium
 Pregnancy Complications 0.885 0.769 – 1.02 0.0859 236 2351 all phecode
674 Other complications of the puerperium NEC Pregnancy Complications 1.06 0.894 – 1.25 0.522 158 1580 all phecode
676
Other disorders of the breast associated with
Other disorders of the breast associated with childbirth and disorders of lactation
 Pregnancy Complications 0.924 0.791 – 1.08 0.316 184 1814 all phecode
681 Superficial cellulitis and abscess Dermatologic 1.04 1.01 – 1.07 0.00853 6500 38394 all phecode
681.1 Cellulitis and abscess of fingers/toes Dermatologic 1.01 0.95 – 1.07 0.774 1256 11462 all phecode
681.2 Cellulitis and abscess of face/neck Dermatologic 1.03 0.965 – 1.1 0.368 1007 9981 all phecode
681.3 Cellulitis and abscess of arm/hand Dermatologic 1.07 1.02 – 1.12 0.00438 2123 19952 all phecode
681.5 Cellulitis and abscess of leg, except foot Dermatologic 1.07 1.02 – 1.12 0.00323 2252 20944 all phecode
681.6 Cellulitis and abscess of foot, toe Dermatologic 1.07 1.02 – 1.12 0.00845 1820 16893 all phecode
681.7 Cellulitis and abscess of trunk Dermatologic 1.05 0.993 – 1.11 0.0879 1572 15588 all phecode
686
Other local infections of skin and subcutaneous
Other local infections of skin and subcutaneous tissue
 Dermatologic 1 0.957 – 1.05 0.983 2257 21750 all phecode
686.1 Carbuncle and furuncle Dermatologic 1.01 0.928 – 1.11 0.761 558 5504 all phecode
686.2 Impetigo Dermatologic 1 0.902 – 1.11 0.977 414 4117 all phecode
686.3 Pilonidal cyst Dermatologic 0.953 0.806 – 1.13 0.576 160 1594 all phecode
686.4 Pyogenic granuloma Dermatologic 0.941 0.801 – 1.11 0.46 158 1570 all phecode
686.5 Pyoderma Dermatologic 0.833 0.641 – 1.08 0.171 63 630 all phecode
687 Symptoms affecting skin Dermatologic 0.957 0.909 – 1.01 0.0928 1690 16343 all phecode
687.1 Rash and other nonspecific skin eruption Dermatologic 0.991 0.965 – 1.02 0.522 7007 34623 all phecode
687.3 Changes in skin texture Dermatologic 1.01 0.911 – 1.12 0.842 415 4121 all phecode
687.4 Disturbance of skin sensation Dermatologic 0.99 0.963 – 1.02 0.489 6375 34216 all phecode
689 Disorder of skin and subcutaneous tissue NOS Dermatologic 0.982 0.959 – 1.01 0.125 9311 37335 all phecode
690 Erythematosquamous dermatosis Dermatologic 0.948 0.919 – 0.977 0.000551 5184 31581 all phecode
690.1 Seborrheic dermatitis Dermatologic 0.948 0.919 – 0.977 0.000571 5174 31553 all phecode
691 Congenital anomalies of skin Dermatologic 0.963 0.88 – 1.05 0.419 541 5337 all phecode
691.3 Congenital pigmentary anomalies of skin Dermatologic 0.964 0.745 – 1.25 0.781 62 613 all phecode
694 Dyschromia and Vitiligo Dermatologic 0.959 0.913 – 1.01 0.089 1861 17936 all phecode
694.1 Vitiligo Dermatologic 1.02 0.855 – 1.22 0.805 137 1347 all phecode
694.2 Other dyschromia Dermatologic 0.956 0.908 – 1.01 0.0854 1674 16183 all phecode
694.3 Vascular disorders of skin Dermatologic 1.1 0.88 – 1.38 0.394 82 819 all phecode
695 Erythematous conditions Dermatologic 1 0.968 – 1.03 0.963 4120 30247 all phecode
695.1 Toxic erythema Dermatologic 1.13 0.879 – 1.46 0.332 70 688 all phecode
695.2 Bullous dermatoses Dermatologic 1.11 0.878 – 1.39 0.391 85 805 all phecode
695.3 Rosacea Dermatologic 0.96 0.914 – 1.01 0.112 1816 17663 all phecode
695.4 Lupus (localized and systemic) Dermatologic 1.04 0.954 – 1.13 0.404 672 6686 all phecode
695.41 Cutaneous lupus erythematosus Dermatologic 1.01 0.883 – 1.16 0.863 247 2437 all phecode
695.42 Systemic lupus erythematosus Dermatologic 1.03 0.944 – 1.12 0.523 637 6337 all phecode
695.7 Prurigo and Lichen Dermatologic 0.967 0.886 – 1.05 0.446 605 5986 all phecode
695.8 Other specified erythematous conditions Dermatologic 1.06 0.979 – 1.14 0.16 812 7980 all phecode
695.81 Erythema nodosum Dermatologic 1.11 0.831 – 1.49 0.475 55 550 all phecode
695.9 Unspecified erythematous condition Dermatologic 1.07 0.988 – 1.16 0.0951 679 6756 all phecode
696 Psoriasis and related disorders Dermatologic 1.01 0.955 – 1.07 0.713 1401 13832 all phecode
696.3 Pityriasis Dermatologic 0.929 0.745 – 1.16 0.516 92 904 all phecode
696.4 Psoriasis Dermatologic 1.02 0.959 – 1.08 0.567 1311 12976 all phecode
696.41 Psoriasis vulgaris Dermatologic 1.02 0.955 – 1.08 0.622 1200 11867 all phecode
696.42 Psoriatic arthropathy Dermatologic 1.03 0.912 – 1.17 0.613 282 2810 all phecode
697 Sarcoidosis Dermatologic 0.96 0.855 – 1.08 0.484 333 3330 all phecode
698 Pruritus and related conditions Dermatologic 0.954 0.912 – 0.997 0.0373 2254 21889 all phecode
700 Corns and callosities Dermatologic 0.993 0.936 – 1.05 0.816 1373 10894 all phecode
701
Other hypertrophic and atrophic conditions of
Other hypertrophic and atrophic conditions of skin
 Dermatologic 0.983 0.959 – 1.01 0.197 7651 38050 all phecode
701.1 Keratoderma, acquired Dermatologic 0.992 0.908 – 1.08 0.858 567 5524 all phecode
701.2 Scar conditions and fibrosis of skin Dermatologic 0.991 0.947 – 1.04 0.687 2184 21550 all phecode
701.3 Circumscribed scleroderma Dermatologic 0.963 0.881 – 1.05 0.404 571 5660 all phecode
701.4 Keloid scar Dermatologic 0.96 0.878 – 1.05 0.374 578 5716 all phecode
701.5 Abnormal granulation tissue Dermatologic 0.95 0.856 – 1.05 0.336 400 3982 all phecode
702
Degenerative skin conditions and other
Degenerative skin conditions and other dermatoses
 Dermatologic 0.954 0.928 – 0.98 0.000741 6956 29525 all phecode
702.1 Actinic keratosis Dermatologic 0.958 0.926 – 0.991 0.0128 4171 26529 all phecode
702.2 Seborrheic keratosis Dermatologic 0.937 0.91 – 0.966 2.17e-05 5480 31552 all phecode
702.4 Degenerative skin disorders Dermatologic 0.973 0.778 – 1.22 0.81 86 832 all phecode
703 Diseases of nail, NOS Dermatologic 0.999 0.948 – 1.05 0.97 1650 14562 all phecode
703.1 Ingrowing nail Dermatologic 0.995 0.928 – 1.07 0.892 920 8597 all phecode
704 Diseases of hair and hair follicles Dermatologic 0.959 0.923 – 0.996 0.0291 3118 29542 all phecode
704.1 Alopecia Dermatologic 0.926 0.875 – 0.98 0.0081 1408 13871 all phecode
704.11 Alopecia Areata Dermatologic 0.925 0.734 – 1.17 0.513 82 811 all phecode
704.12 Telogen effluvium Dermatologic 0.763 0.595 – 0.978 0.0327 63 615 all phecode
704.2 Hirsutism Dermatologic 1.03 0.913 – 1.16 0.632 299 2946 all phecode
704.8
Other specified diseases of hair and hair
Other specified diseases of hair and hair follicles
 Dermatologic 0.967 0.919 – 1.02 0.195 1752 17189 all phecode
705 Disorders of sweat glands Dermatologic 1.05 0.962 – 1.14 0.29 603 6012 all phecode
705.1 Dyshidrosis Dermatologic 0.931 0.788 – 1.1 0.405 154 1540 all phecode
705.3 Hidradenitis Dermatologic 1.19 1.04 – 1.36 0.00944 245 2440 all phecode
705.8 Hyperhidrosis Dermatologic 0.948 0.89 – 1.01 0.0978 1112 10986 all phecode
706 Diseases of sebaceous glands Dermatologic 0.953 0.927 – 0.981 0.000883 5995 39748 all phecode
706.1 Acne Dermatologic 0.936 0.897 – 0.976 0.0019 2594 22570 all phecode
706.2 Sebaceous cyst Dermatologic 0.947 0.91 – 0.985 0.00724 2814 26819 all phecode
706.3 Seborrhea Dermatologic 1.25 0.949 – 1.65 0.112 59 582 all phecode
706.8 Other specified diseases of sebaceous glands Dermatologic 0.979 0.93 – 1.03 0.43 1684 15289 all phecode
707 Chronic ulcer of skin Dermatologic 1.02 0.977 – 1.06 0.41 2871 26816 all phecode
707.1 Decubitus ulcer Dermatologic 1.01 0.941 – 1.09 0.741 825 8119 all phecode
707.2 Chronic ulcer of leg or foot Dermatologic 1.08 1.01 – 1.15 0.0165 1108 9992 all phecode
707.3 Chronic ulcer of unspecified site Dermatologic 0.996 0.945 – 1.05 0.876 1641 16172 all phecode
709 Diffuse diseases of connective tissue Dermatologic 0.994 0.94 – 1.05 0.817 1477 14427 all phecode
709.2 Sicca syndrome Dermatologic 0.955 0.869 – 1.05 0.337 505 4986 all phecode
709.3 Systemic sclerosis Dermatologic 0.995 0.863 – 1.15 0.94 224 2209 all phecode
709.5 Dermatomyositis Dermatologic 1.17 0.942 – 1.45 0.156 92 892 all phecode
709.6
Other specified diffuse diseases of connective
Other specified diffuse diseases of connective tissue
 Dermatologic 1.01 0.815 – 1.26 0.9 90 892 all phecode
709.7 Unspecified diffuse connective tissue disease Dermatologic 1.01 0.939 – 1.08 0.853 917 9089 all phecode
710
Osteomyelitis, periostitis, and other
Osteomyelitis, periostitis, and other infections involving bone
 Musculoskeletal 1.05 0.985 – 1.11 0.144 1254 12103 all phecode
710.1 Osteomyelitis Musculoskeletal 1.06 0.997 – 1.13 0.0608 1203 11636 all phecode
710.11 Acute osteomyelitis Musculoskeletal 1.08 0.986 – 1.17 0.0996 590 5708 all phecode
710.12 Chronic osteomyelitis Musculoskeletal 1.09 0.993 – 1.19 0.0705 531 5163 all phecode
710.19 Unspecified osteomyelitis Musculoskeletal 1.06 0.996 – 1.13 0.0651 1153 11149 all phecode
711 Arthropathy associated with infections Musculoskeletal 0.955 0.862 – 1.06 0.375 410 4099 all phecode
711.1 Pyogenic arthritis Musculoskeletal 0.989 0.876 – 1.12 0.852 290 2900 all phecode
712 Infective connective tissue disorders Musculoskeletal 1.09 0.929 – 1.27 0.296 178 1776 all phecode
713
Arthropathy associated with other disorders
Arthropathy associated with other disorders classified elsewhere
 Musculoskeletal 1.02 0.908 – 1.15 0.73 314 3028 all phecode
713.5
Arthropathy associated with neurological
Arthropathy associated with neurological disorders
 Musculoskeletal 0.988 0.848 – 1.15 0.879 194 1824 all phecode
714
Rheumatoid arthritis and other inflammatory
Rheumatoid arthritis and other inflammatory polyarthropathies
 Musculoskeletal 0.981 0.936 – 1.03 0.41 2086 18159 all phecode
714.1 Rheumatoid arthritis Musculoskeletal 0.975 0.925 – 1.03 0.331 1670 15087 all phecode
714.2 Juvenile rheumatoid arthritis Musculoskeletal 0.852 0.667 – 1.09 0.198 77 767 all phecode
715 Other inflammatory spondylopathies Musculoskeletal 0.942 0.887 – 1 0.0533 1209 11967 all phecode
715.1 Sacroiliitis NEC Musculoskeletal 0.965 0.847 – 1.1 0.588 262 2611 all phecode
715.2 Ankylosing spondylitis Musculoskeletal 0.858 0.746 – 0.988 0.0338 219 2182 all phecode
716 Other arthropathies Musculoskeletal 0.997 0.976 – 1.02 0.812 13482 31305 all phecode
716.1 Unspecified polyarthropathy or polyarthritis Musculoskeletal 0.962 0.824 – 1.12 0.619 192 1920 all phecode
716.2 Unspecified monoarthritis Musculoskeletal 0.966 0.808 – 1.15 0.7 131 1293 all phecode
716.9 Arthropathy NOS Musculoskeletal 0.997 0.975 – 1.02 0.764 13410 31294 all phecode
717 Polymyalgia Rheumatica Musculoskeletal 0.946 0.831 – 1.08 0.403 261 2565 all phecode
720 Spinal stenosis Musculoskeletal 0.99 0.957 – 1.02 0.569 3958 28539 all phecode
720.1 Spinal stenosis of lumbar region Musculoskeletal 0.978 0.94 – 1.02 0.282 2872 23656 all phecode
721 Spondylosis and allied disorders Musculoskeletal 0.978 0.949 – 1.01 0.14 5509 32391 all phecode
721.1 Spondylosis without myelopathy Musculoskeletal 0.977 0.948 – 1.01 0.136 5153 31896 all phecode
721.2 Spondylosis with myelopathy Musculoskeletal 0.999 0.929 – 1.07 0.987 867 8629 all phecode
721.8 Other allied disorders of spine Musculoskeletal 0.839 0.735 – 0.956 0.00862 262 2600 all phecode
722 Intervertebral disc disorders Musculoskeletal 1 0.974 – 1.03 0.918 6284 34317 all phecode
722.1 Displacement of intervertebral disc Musculoskeletal 0.979 0.945 – 1.01 0.248 3591 31411 all phecode
722.3 Schmorl's nodes Musculoskeletal 0.988 0.817 – 1.19 0.898 126 1248 all phecode
722.6 Degeneration of intervertebral disc Musculoskeletal 1.01 0.979 – 1.05 0.441 3957 30744 all phecode
722.7 Intervertebral disc disorder with myelopathy Musculoskeletal 1.09 0.992 – 1.2 0.0739 515 5140 all phecode
722.8 Postlaminectomy syndrome Musculoskeletal 1.03 0.928 – 1.15 0.551 397 3968 all phecode
722.9 Other and unspecified disc disorder Musculoskeletal 0.999 0.952 – 1.05 0.968 1932 19288 all phecode
723 Other disorders of cervical region Musculoskeletal 0.93 0.868 – 0.995 0.036 952 9495 all phecode
723.1 Torticollis Musculoskeletal 0.909 0.799 – 1.03 0.15 254 2522 all phecode
724 Other and unspecified disorders of back Musculoskeletal 0.959 0.928 – 0.992 0.0153 4130 31954 all phecode
724.1 Disorders of sacrum Musculoskeletal 0.934 0.894 – 0.976 0.0025 2307 21902 all phecode
724.2 Disorders of coccyx Musculoskeletal 0.943 0.851 – 1.04 0.262 426 4215 all phecode
724.8 Other symptoms referable to back Musculoskeletal 0.977 0.911 – 1.05 0.503 931 9295 all phecode
724.9 Other unspecified back disorders Musculoskeletal 0.961 0.908 – 1.02 0.165 1412 14087 all phecode
726 Peripheral enthesopathies and allied syndromes Musculoskeletal 0.962 0.94 – 0.985 0.0014 9917 30176 all phecode
726.1 Enthesopathy Musculoskeletal 0.963 0.938 – 0.989 0.00481 7507 30106 all phecode
726.2 Synoviopathy Musculoskeletal 0.915 0.857 – 0.978 0.0088 1015 9987 all phecode
726.3 Bursitis Musculoskeletal 0.959 0.913 – 1.01 0.103 1829 16722 all phecode
726.4 Calcaneal spur; Exostosis NOS Musculoskeletal 0.918 0.863 – 0.976 0.00642 1193 11485 all phecode
727 Other disorders of synovium, tendon, and bursa Musculoskeletal 0.967 0.941 – 0.992 0.0114 7425 30105 all phecode
727.1 Synovitis and tenosynovitis Musculoskeletal 0.953 0.917 – 0.99 0.014 3092 24998 all phecode
727.2 Bursitis disorders Musculoskeletal 0.962 0.868 – 1.07 0.456 419 4112 all phecode
727.4 Ganglion and cyst of synovium, tendon, and bursa Musculoskeletal 0.966 0.913 – 1.02 0.227 1400 13621 all phecode
727.5 Rupture of synovium Musculoskeletal 1.03 0.933 – 1.13 0.576 480 4672 all phecode
727.6 Rupture of tendon, nontraumatic Musculoskeletal 0.984 0.943 – 1.03 0.464 2461 21948 all phecode
727.7 Contracture of tendon (sheath) Musculoskeletal 0.969 0.887 – 1.06 0.475 591 5893 all phecode
727.8 Plica syndrome Musculoskeletal 0.902 0.753 – 1.08 0.26 130 1264 all phecode
728 Disorders of muscle, ligament, and fascia Musculoskeletal 0.991 0.959 – 1.02 0.576 4546 29473 all phecode
728.1 Muscular calcification and ossification Musculoskeletal 0.942 0.749 – 1.19 0.611 85 843 all phecode
728.2 Laxity of ligament or hypermobility syndrome Musculoskeletal 0.945 0.834 – 1.07 0.378 297 2949 all phecode
728.7 Fasciitis Musculoskeletal 0.96 0.922 – 1 0.0485 2814 23463 all phecode
728.71
Contracture of palmar fascia [Dupuytren's
Contracture of palmar fascia [Dupuytren's disease]
 Musculoskeletal 0.97 0.873 – 1.08 0.57 419 4138 all phecode
729 Other disorders of soft tissues Musculoskeletal 1.02 0.98 – 1.05 0.398 3642 27471 all phecode
729.1 Rheumatism, unspecified and fibrositis Musculoskeletal 1.06 0.841 – 1.34 0.618 74 726 all phecode
729.3 Panniculitis Musculoskeletal 1.01 0.835 – 1.22 0.929 119 1174 all phecode
729.7 Nontraumatic compartment syndrome Musculoskeletal 1.13 0.87 – 1.46 0.364 67 664 all phecode
731
Osteitis deformans and osteopathies associated
Osteitis deformans and osteopathies associated with other disorders classified elsewhere
 Musculoskeletal 1.13 0.98 – 1.31 0.0906 210 2091 all phecode
732 Osteochondropathies Musculoskeletal 1.02 0.915 – 1.14 0.729 361 3604 all phecode
732.1 Juvenile osteochondrosis Musculoskeletal 0.988 0.851 – 1.15 0.872 198 1969 all phecode
732.7 Osteochondritis dissecans Musculoskeletal 1.09 0.879 – 1.35 0.433 90 882 all phecode
733 Other disorders of bone and cartilage Musculoskeletal 0.956 0.925 – 0.988 0.00711 4543 26941 all phecode
733.2 Cyst of bone Musculoskeletal 0.928 0.795 – 1.08 0.343 190 1900 all phecode
733.4 Aseptic necrosis of bone Musculoskeletal 0.926 0.844 – 1.02 0.105 518 5160 all phecode
733.6 Costochondritis Musculoskeletal 0.946 0.848 – 1.06 0.329 357 3562 all phecode
733.8 Malunion and nonunion of fracture Musculoskeletal 1 0.931 – 1.08 0.963 822 8205 all phecode
733.9 Chondromalacia Musculoskeletal 0.897 0.728 – 1.11 0.309 96 960 all phecode
735 Acquired foot deformities Musculoskeletal 0.97 0.935 – 1.01 0.101 3417 29622 all phecode
735.1 Flat foot Musculoskeletal 0.967 0.889 – 1.05 0.436 620 6092 all phecode
735.2 Acquired toe deformities Musculoskeletal 0.942 0.889 – 0.999 0.0463 1323 11983 all phecode
735.21 Hammer toe (acquired) Musculoskeletal 0.943 0.876 – 1.02 0.12 825 7494 all phecode
735.23 Hallux rigidus Musculoskeletal 0.877 0.791 – 0.973 0.0134 405 4005 all phecode
735.3 Hallux valgus (Bunion) Musculoskeletal 0.959 0.907 – 1.01 0.131 1470 14295 all phecode
736 Other acquired deformities of limbs Musculoskeletal 0.966 0.928 – 1.01 0.0942 2763 26555 all phecode
736.1 Acquired deformities of forearm Musculoskeletal 1.05 0.854 – 1.28 0.664 104 1033 all phecode
736.2 Acquired deformities of finger Musculoskeletal 1.05 0.909 – 1.22 0.496 215 2142 all phecode
736.3 Acquired deformities of hip Musculoskeletal 1.01 0.78 – 1.3 0.961 60 590 all phecode
736.4 Genu valgum or varum (acquired) Musculoskeletal 0.874 0.777 – 0.983 0.0244 325 3247 all phecode
736.5 Acquired deformities of knee Musculoskeletal 0.903 0.791 – 1.03 0.135 246 2460 all phecode
736.6 Unequal leg length (acquired) Musculoskeletal 0.966 0.861 – 1.08 0.553 339 3365 all phecode
737 Curvature of spine Musculoskeletal 0.923 0.875 – 0.974 0.0032 1566 15543 all phecode
737.1 Kyphosis (acquired) Musculoskeletal 0.955 0.867 – 1.05 0.356 479 4748 all phecode
737.2 Lordosis (acquired) Musculoskeletal 0.96 0.749 – 1.23 0.744 70 700 all phecode
737.3 Kyphoscoliosis and scoliosis Musculoskeletal 0.91 0.856 – 0.967 0.00222 1203 11982 all phecode
738 Other acquired musculoskeletal deformity Musculoskeletal 0.974 0.933 – 1.02 0.233 2443 24187 all phecode
738.4 Acquired spondylolisthesis Musculoskeletal 0.993 0.93 – 1.06 0.825 1057 10542 all phecode
739 Contracture of joint Musculoskeletal 1.07 0.98 – 1.16 0.136 621 6207 all phecode
740 Osteoarthrosis Musculoskeletal 0.99 0.97 – 1.01 0.351 16169 30268 all phecode
740.1 Osteoarthritis; localized Musculoskeletal 0.962 0.935 – 0.989 0.00562 7005 27422 all phecode
740.11 Osteoarthrosis, localized, primary Musculoskeletal 0.959 0.931 – 0.987 0.00487 6176 26155 all phecode
740.12 Osteoarthrosis, localized, secondary Musculoskeletal 0.918 0.847 – 0.994 0.0359 713 7116 all phecode
740.2 Osteoarthrosis, generalized Musculoskeletal 0.914 0.866 – 0.965 0.00124 1609 12092 all phecode
740.3
Osteoarthrosis involving more than one site
Osteoarthrosis involving more than one site, but not specified as generalized
 Musculoskeletal 1.02 0.912 – 1.14 0.746 373 3586 all phecode
740.9 Osteoarthrosis NOS Musculoskeletal 0.989 0.969 – 1.01 0.307 15497 30141 all phecode
741 Symptoms and disorders of the joints Musculoskeletal 0.977 0.954 – 1 0.0654 8555 35884 all phecode
741.1 Ankylosis of joint Musculoskeletal 0.922 0.805 – 1.06 0.236 245 2445 all phecode
741.2 Stiffness of joint Musculoskeletal 1 0.942 – 1.06 0.999 1268 12594 all phecode
741.3 Difficulty in walking Musculoskeletal 1.01 0.966 – 1.05 0.718 2558 23116 all phecode
741.4 Joint effusions Musculoskeletal 0.973 0.933 – 1.02 0.208 2493 24199 all phecode
741.5 Hemarthrosis Musculoskeletal 0.852 0.689 – 1.05 0.137 94 937 all phecode
741.6 Villonodular synovitis Musculoskeletal 0.967 0.754 – 1.24 0.792 68 666 all phecode
742 Derangement of joint, non-traumatic Musculoskeletal 0.952 0.922 – 0.983 0.00291 4404 33771 all phecode
742.1 Loose body in joint Musculoskeletal 1 0.847 – 1.19 0.967 156 1554 all phecode
742.2
Pathological, developmental or recurrent
Pathological, developmental or recurrent dislocation
 Musculoskeletal 0.869 0.767 – 0.984 0.027 280 2792 all phecode
742.8 Articular cartilage disorder Musculoskeletal 0.974 0.851 – 1.11 0.697 245 2450 all phecode
742.9 Other derangement of joint Musculoskeletal 0.954 0.922 – 0.986 0.0055 4107 32972 all phecode
743
Osteoporosis, osteopenia and pathological
Osteoporosis, osteopenia and pathological fracture
 Musculoskeletal 0.974 0.951 – 0.998 0.0372 9223 36921 all phecode
743.1 Osteoporosis Musculoskeletal 0.975 0.939 – 1.01 0.181 3712 19477 all phecode
743.11 Osteoporosis NOS Musculoskeletal 0.975 0.939 – 1.01 0.188 3657 19276 all phecode
743.12 Senile osteoporosis Musculoskeletal 0.916 0.844 – 0.993 0.0331 703 5804 all phecode
743.13 Other specified osteoporosis Musculoskeletal 0.963 0.855 – 1.08 0.535 321 3141 all phecode
743.2 Pathologic fracture Musculoskeletal 0.945 0.887 – 1.01 0.0826 1112 10563 all phecode
743.21 Pathologic fracture of vertebrae Musculoskeletal 0.954 0.865 – 1.05 0.348 475 4629 all phecode
743.22 Pathologic fracture of femur Musculoskeletal 1 0.837 – 1.2 0.995 143 1391 all phecode
743.4 Stress fracture Musculoskeletal 1.03 0.926 – 1.14 0.607 407 4046 all phecode
743.9
Osteopenia or other disorder of bone and
Osteopenia or other disorder of bone and cartilage
 Musculoskeletal 0.969 0.943 – 0.996 0.023 6970 35237 all phecode
745 Pain in joint Musculoskeletal 0.963 0.945 – 0.981 9.94e-05 19848 26918 all phecode
747 Cardiac and circulatory congenital anomalies Congenital Anomalies 1.01 0.962 – 1.05 0.79 2236 22256 all phecode
747.1 Cardiac congenital anomalies Congenital Anomalies 1.02 0.973 – 1.08 0.363 1767 17598 all phecode
747.11 Cardiac shunt/ heart septal defect Congenital Anomalies 0.974 0.897 – 1.06 0.536 650 6497 all phecode
747.12 Valvular heart disease/ heart chambers Congenital Anomalies 1.02 0.939 – 1.1 0.702 751 7480 all phecode
747.13 Congenital anomalies of great vessels Congenital Anomalies 1 0.905 – 1.11 0.932 410 4090 all phecode
747.2
Congenital anomalies of peripheral vascular
Congenital anomalies of peripheral vascular system
 Congenital Anomalies 0.971 0.883 – 1.07 0.536 501 5010 all phecode
748 Anomalies of respiratory system, congenital Congenital Anomalies 1.02 0.841 – 1.24 0.826 111 1110 all phecode
749 Congenital anomalies of face and neck Congenital Anomalies 1.07 0.98 – 1.17 0.13 555 5549 all phecode
749.1 Cleft palate Congenital Anomalies 1.15 0.938 – 1.42 0.176 97 970 all phecode
749.2 Congenital anomalies of skull and face bones Congenital Anomalies 1.01 0.832 – 1.24 0.89 105 1041 all phecode
750 Digestive congenital anomalies Congenital Anomalies 1.01 0.942 – 1.09 0.754 893 8919 all phecode
750.1 Upper gastrointestinal congenital anomalies Congenital Anomalies 0.954 0.853 – 1.07 0.407 366 3655 all phecode
750.11 Esophageal atresia/tracheoesophageal fistula Congenital Anomalies 0.856 0.703 – 1.04 0.123 119 1185 all phecode
750.13 Congenital anomalies of mouth/tongue Congenital Anomalies 0.963 0.779 – 1.19 0.729 99 982 all phecode
750.14 Congenital anomalies of esophagus Congenital Anomalies 0.838 0.698 – 1.01 0.0588 134 1332 all phecode
750.15 Congenital anomalies of stomach Congenital Anomalies 1.09 0.83 – 1.43 0.532 60 593 all phecode
750.2 Lower gastrointestinal congenital anomalies Congenital Anomalies 1.05 0.955 – 1.15 0.328 531 5300 all phecode
750.21 Congenital anomalies of intestine Congenital Anomalies 1.07 0.951 – 1.2 0.258 313 3129 all phecode
750.22
Congenital anomaly of gallbladder, bile ducts
Congenital anomaly of gallbladder, bile ducts, liver, pancreas
 Congenital Anomalies 0.993 0.862 – 1.14 0.92 222 2214 all phecode
751 Genitourinary congenital anomalies Congenital Anomalies 1.02 0.971 – 1.07 0.468 2008 19975 all phecode
751.1 Congenital anomalies of genital organs Congenital Anomalies 0.957 0.877 – 1.04 0.322 574 5740 all phecode
751.11 Congenital anomalies of female genital organs Congenital Anomalies 0.911 0.819 – 1.01 0.0853 384 3840 all phecode
751.12 Congenital anomalies of male genital organs Congenital Anomalies 1.05 0.883 – 1.24 0.598 153 1527 all phecode
751.2 Congenital anomalies of urinary system Congenital Anomalies 1.05 0.988 – 1.11 0.122 1379 13704 all phecode
751.21 Cystic kidney disease Congenital Anomalies 1.04 0.974 – 1.12 0.23 976 9685 all phecode
751.22 Other specified congenital anomalies of kidney Congenital Anomalies 1.06 0.935 – 1.2 0.37 294 2927 all phecode
751.3 Obstructive genitourinary defect Congenital Anomalies 0.966 0.827 – 1.13 0.667 182 1809 all phecode
752 Nervous system congenital anomalies Congenital Anomalies 1.04 0.976 – 1.11 0.225 1133 11313 all phecode
752.1 Neural tube defects Congenital Anomalies 1.05 0.983 – 1.13 0.14 923 9209 all phecode
752.11 Spina bifida Congenital Anomalies 1.01 0.868 – 1.18 0.873 176 1760 all phecode
752.2
Other specified congenital anomalies of nervous
Other specified congenital anomalies of nervous system
 Congenital Anomalies 1.02 0.888 – 1.17 0.772 232 2320 all phecode
753 Congenital anomalies of the eye Congenital Anomalies 1.07 0.928 – 1.23 0.361 207 2051 all phecode
753.1 Congenital cataract and lens anomalies Congenital Anomalies 1.05 0.82 – 1.34 0.709 58 580 all phecode
753.2 Congenital anomalies of posterior segment of eye Congenital Anomalies 1.14 0.862 – 1.51 0.354 56 546 all phecode
754 Congenital musculoskeletal deformities of spine Congenital Anomalies 1.01 0.949 – 1.07 0.784 1216 12116 all phecode
754.1 Lumbosacral spondylolysis, congenital Congenital Anomalies 0.998 0.825 – 1.21 0.987 135 1333 all phecode
754.2 Spondylolisthesis, congenital Congenital Anomalies 1.06 0.973 – 1.16 0.178 558 5570 all phecode
755 Congenital anomalies of limbs Congenital Anomalies 0.984 0.911 – 1.06 0.687 747 7458 all phecode
755.1 Congenital deformities of feet Congenital Anomalies 1.05 0.937 – 1.17 0.427 368 3663 all phecode
755.4
Congenital anomalies of upper limb, including
Congenital anomalies of upper limb, including shoulder girdle
 Congenital Anomalies 0.97 0.767 – 1.23 0.8 74 740 all phecode
755.6
Other congenital anomalies of lower limb
Other congenital anomalies of lower limb, including pelvic girdle
 Congenital Anomalies 0.906 0.806 – 1.02 0.0974 321 3205 all phecode
755.61 Congenital hip dysplasia and deformity Congenital Anomalies 0.942 0.807 – 1.1 0.444 185 1847 all phecode
756 Other congenital musculoskeletal anomalies Congenital Anomalies 0.944 0.891 – 0.999 0.0462 1358 13579 all phecode
756.1 Congenital anomalies of abdominal wall; diaphram Congenital Anomalies 0.886 0.693 – 1.13 0.337 68 680 all phecode
756.2
Pectus and other congenital anomalies of
Pectus and other congenital anomalies of ribs/sternum
 Congenital Anomalies 0.965 0.757 – 1.23 0.777 71 694 all phecode
756.3
Congenital anomalies of muscle, tendon, fascia
Congenital anomalies of muscle, tendon, fascia, and connective tissue
 Congenital Anomalies 0.871 0.776 – 0.977 0.0185 335 3346 all phecode
756.5 Congenital osteodystrophies Congenital Anomalies 0.979 0.916 – 1.05 0.522 1003 10014 all phecode
757 Congenital anomalies of the integument Congenital Anomalies 0.995 0.895 – 1.1 0.921 401 4001 all phecode
758 Chromosomal anomalies and genetic disorders Congenital Anomalies 0.866 0.742 – 1.01 0.0664 185 1845 all phecode
758.1 Chromosomal anomalies Congenital Anomalies 0.814 0.675 – 0.983 0.032 135 1349 all phecode
759 Other and unspecified congenital anomalies Congenital Anomalies 0.904 0.826 – 0.99 0.0287 557 5566 all phecode
759.1 Anomalies of endocrine glands, congenital Congenital Anomalies 0.945 0.734 – 1.22 0.659 71 710 all phecode
760 Back pain Symptoms 0.972 0.953 – 0.992 0.00513 16037 30719 all phecode
761 Cervicalgia Symptoms 0.968 0.942 – 0.995 0.0183 6528 39755 all phecode
763
Thoracic or lumbosacral neuritis or
Thoracic or lumbosacral neuritis or radiculitis, unspecified
 Symptoms 0.966 0.932 – 1 0.0521 3657 32599 all phecode
764 Sciatica Symptoms 0.976 0.941 – 1.01 0.174 3542 32015 all phecode
765 Cervical radiculitis Symptoms 0.954 0.908 – 1 0.0654 1799 17851 all phecode
766 Neuralgia, neuritis, and radiculitis NOS Symptoms 0.975 0.946 – 1 0.0946 5124 37132 all phecode
767 Cervicocranial/Cervicobrachial syndrome Symptoms 1.12 0.931 – 1.35 0.229 117 1168 all phecode
769 Nonallopathic lesions NEC Symptoms 1.01 0.95 – 1.08 0.718 1131 11220 all phecode
770 Myalgia and myositis unspecified Symptoms 0.98 0.951 – 1.01 0.173 5533 34303 all phecode
771 Musculoskeletal symptoms referable to limbs Symptoms 1.01 0.982 – 1.04 0.419 4799 35575 all phecode
771.1 Swelling of limb Symptoms 1.03 0.997 – 1.06 0.0809 5743 35539 all phecode
771.2 Cramp of limb Symptoms 1.05 0.98 – 1.12 0.174 1079 10568 all phecode
772 Symptoms of the muscles Symptoms 0.934 0.891 – 0.978 0.00406 2042 20221 all phecode
772.1 Muscular wasting and disuse atrophy Symptoms 1.05 0.947 – 1.17 0.348 422 4199 all phecode
772.2 Spasm of muscle Symptoms 0.995 0.952 – 1.04 0.819 2299 22726 all phecode
772.3 Muscle weakness Symptoms 1 0.965 – 1.04 0.841 2949 28064 all phecode
772.4 Rhabdomyolysis Symptoms 1.04 0.886 – 1.23 0.608 159 1572 all phecode
772.6 Facial weakness Symptoms 1.04 0.943 – 1.14 0.446 478 4742 all phecode
780 Hypothermia/Chills Symptoms 0.993 0.9 – 1.1 0.895 453 4514 all phecode
781
Symptoms involving nervous and musculoskeletal
Symptoms involving nervous and musculoskeletal systems
 Symptoms 0.985 0.946 – 1.02 0.446 2822 26225 all phecode
781.1 Loss of height Symptoms 0.995 0.829 – 1.19 0.957 130 1269 all phecode
781.2 Abnormal posture Symptoms 1.1 0.836 – 1.46 0.485 57 567 all phecode
782.3 Edema Symptoms 1.04 1.01 – 1.07 0.00385 5874 36788 all phecode
782.6 Pallor and flushing Symptoms 1.05 0.976 – 1.12 0.203 927 9252 all phecode
783 Fever of unknown origin Symptoms 1.03 0.998 – 1.06 0.0639 5733 40720 all phecode
783.1 Postprocedural fever Symptoms 1.06 0.941 – 1.2 0.328 300 2992 all phecode
785 Abdominal pain Symptoms 0.992 0.972 – 1.01 0.395 16458 30297 all phecode
788 Syncope and collapse Symptoms 0.982 0.95 – 1.02 0.308 3851 35832 all phecode
789 Nausea and vomiting Symptoms 1.02 0.994 – 1.04 0.159 10568 36098 all phecode
789.1 Persistent vomiting Symptoms 0.977 0.907 – 1.05 0.541 798 7924 all phecode
790 Nonspecific findings on examination of blood Symptoms 1.08 1.03 – 1.12 0.000986 2363 22690 all phecode
790.1 Elevated sedimentation rate Symptoms 1.02 0.889 – 1.17 0.766 236 2322 all phecode
790.6 Other abnormal blood chemistry Symptoms 1.03 1 – 1.06 0.032 7539 37788 all phecode
790.8 Elevated C-reactive protein (CRP) Symptoms 0.974 0.863 – 1.1 0.672 309 3075 all phecode
790.9 Abnormal arterial blood gases Symptoms 1.03 0.87 – 1.23 0.7 155 1521 all phecode
791 Gangrene Symptoms 1.14 1.01 – 1.28 0.0312 313 3115 all phecode
792
Abnormal Papanicolaou smear of cervix and
Abnormal Papanicolaou smear of cervix and cervical HPV
 Genitourinary 0.954 0.915 – 0.994 0.0242 2820 14872 all phecode
792.1
Papanicolaou smear of cervix or vagina with
Papanicolaou smear of cervix or vagina with atypical squamous cells
 Genitourinary 0.971 0.911 – 1.03 0.364 1100 9861 all phecode
794
Abnormal results of other function studies
Abnormal results of other function studies (bladder, pancreas, placenta, spleen, etc)
 Symptoms 1.01 0.921 – 1.11 0.829 515 5133 all phecode
795
Other and nonspecific abnormal cytological
Other and nonspecific abnormal cytological, histological and immunological findings
 Symptoms 1.01 0.965 – 1.06 0.68 2182 20242 all phecode
795.8 Abnormal tumor markers Symptoms 0.999 0.95 – 1.05 0.971 1745 15551 all phecode
795.81 Elevated carcinoembryonic antigen [CEA] Symptoms 0.952 0.727 – 1.25 0.719 61 605 all phecode
795.82 Elevated cancer antigen 125 [CA 125] Symptoms 1.09 0.939 – 1.26 0.264 201 2000 all phecode
796 Elevated prostate specific antigen [PSA] Genitourinary 0.966 0.92 – 1.01 0.168 2125 9930 all phecode
797 Shock Symptoms 1.13 1.04 – 1.24 0.00451 605 6050 all phecode
797.1 Cardiogenic shock Symptoms 1.22 1.07 – 1.4 0.00398 242 2420 all phecode
798 Malaise and fatigue Symptoms 0.983 0.961 – 1 0.114 11539 35196 all phecode
798.1 Chronic fatigue syndrome Symptoms 0.979 0.932 – 1.03 0.412 1823 17795 all phecode
800 Fracture of lower limb Injuries & Poisonings 0.981 0.94 – 1.03 0.399 2344 22951 all phecode
800.1 Fracture of neck of femur Injuries & Poisonings 1.02 0.931 – 1.12 0.656 512 4961 all phecode
800.2 Fracture of unspecified part of femur Injuries & Poisonings 0.99 0.913 – 1.07 0.805 670 6582 all phecode
800.3 Fracture of tibia and fibula Injuries & Poisonings 0.977 0.911 – 1.05 0.514 898 8966 all phecode
800.4 Fracture of patella Injuries & Poisonings 0.952 0.851 – 1.06 0.387 346 3456 all phecode
801 Fracture of ankle and foot Injuries & Poisonings 0.986 0.944 – 1.03 0.524 2358 22645 all phecode
801.1 Fracture of foot Injuries & Poisonings 1.02 0.955 – 1.08 0.609 1120 11178 all phecode
802 Fracture of pelvis Injuries & Poisonings 0.987 0.886 – 1.1 0.805 380 3765 all phecode
803 Fracture of upper limb Injuries & Poisonings 0.925 0.883 – 0.969 0.000954 2051 20360 all phecode
803.1 Fracture of humerus Injuries & Poisonings 0.945 0.875 – 1.02 0.156 734 7322 all phecode
803.2 Fracture of radius and ulna Injuries & Poisonings 0.927 0.87 – 0.987 0.0187 1112 11075 all phecode
803.21 Colles' fracture Injuries & Poisonings 1 0.888 – 1.14 0.942 291 2904 all phecode
803.3 Fracture of clavicle or scapula Injuries & Poisonings 0.892 0.814 – 0.978 0.0146 514 5140 all phecode
804 Fracture of hand or wrist Injuries & Poisonings 0.936 0.888 – 0.987 0.0137 1628 16042 all phecode
805
Fracture of vertebral column without mention of
Fracture of vertebral column without mention of spinal cord injury
 Injuries & Poisonings 0.959 0.905 – 1.02 0.156 1336 13242 all phecode
807 Fracture of ribs Injuries & Poisonings 0.995 0.918 – 1.08 0.908 683 6815 all phecode
809 Fracture of unspecified bones Injuries & Poisonings 0.968 0.931 – 1.01 0.1 2941 28633 all phecode
816 Cerebral laceration and contusion Injuries & Poisonings 1.24 0.933 – 1.64 0.14 54 531 all phecode
817 Concussion Injuries & Poisonings 0.981 0.918 – 1.05 0.57 1018 10149 all phecode
818 Intracranial hemorrhage (injury) Injuries & Poisonings 0.949 0.842 – 1.07 0.394 311 3104 all phecode
818.1 Subdural hemorrhage (injury) Injuries & Poisonings 0.979 0.778 – 1.23 0.854 90 895 all phecode
818.2 Subarachnoid hemorrhage (injury) Injuries & Poisonings 1.12 0.909 – 1.39 0.282 97 970 all phecode
819
Skull and face fracture and other intercranial
Skull and face fracture and other intercranial injury
 Injuries & Poisonings 0.969 0.927 – 1.01 0.158 2287 22671 all phecode
830 Dislocation Injuries & Poisonings 0.973 0.94 – 1.01 0.115 3862 34720 all phecode
835 Internal derangement of knee Injuries & Poisonings 0.982 0.939 – 1.03 0.434 2231 21628 all phecode
836 Traumatic arthropathy Injuries & Poisonings 0.996 0.906 – 1.09 0.932 496 4954 all phecode
840 Sprains and strains Injuries & Poisonings 0.948 0.925 – 0.972 3.29e-05 7838 37998 all phecode
840.1 Muscle/tendon sprain Injuries & Poisonings 0.86 0.785 – 0.943 0.00125 537 5356 all phecode
840.2 Rotator cuff (capsule) sprain Injuries & Poisonings 0.959 0.91 – 1.01 0.115 1640 16263 all phecode
840.3 Joint/ligament sprain Injuries & Poisonings 0.923 0.887 – 0.961 8.37e-05 2875 24879 all phecode
841 Sprains and strains of back and neck Injuries & Poisonings 0.892 0.846 – 0.941 2.42e-05 1583 15592 all phecode
842 Other sprains and strains Injuries & Poisonings 0.948 0.896 – 1 0.059 1407 13924 all phecode
850 Hemorrhage or hematoma complicating a procedure Injuries & Poisonings 1.05 1 – 1.1 0.0444 2072 20649 all phecode
851
Complications of transplants and reattached
Complications of transplants and reattached limbs
 Injuries & Poisonings 1.06 1.02 – 1.11 0.00156 2982 27545 all phecode
853 Complication of colostomy or enterostomy Injuries & Poisonings 1.14 1.03 – 1.25 0.0121 460 4600 all phecode
854
Complications of cardiac/vascular device
Complications of cardiac/vascular device, implant, and graft
 Injuries & Poisonings 1.1 1.05 – 1.15 6.32e-05 1985 19675 all phecode
855
Complication of nervous system device, implant
Complication of nervous system device, implant, and graft
 Injuries & Poisonings 1.07 0.942 – 1.22 0.287 264 2640 all phecode
856
Vascular complications of surgery and medical
Vascular complications of surgery and medical procedures
 Injuries & Poisonings 0.988 0.872 – 1.12 0.847 293 2929 all phecode
857
Mechanical complication of unspecified
Mechanical complication of unspecified genitourinary device, implant, and graft
 Injuries & Poisonings 1.03 0.969 – 1.09 0.36 1310 13087 all phecode
858 Complication of internal orthopedic device Injuries & Poisonings 1 0.956 – 1.05 0.989 2213 21944 all phecode
859
Complication due to other implant and internal
Complication due to other implant and internal device
 Injuries & Poisonings 1.01 0.968 – 1.06 0.575 2110 21070 all phecode
860 Bone marrow or stem cell transplant Neoplasms 1.22 1.04 – 1.44 0.0172 166 1660 all phecode
870 Open wounds of head; neck; and trunk Injuries & Poisonings 1 0.972 – 1.04 0.803 4117 36734 all phecode
870.1 Open wound or laceration of eye or eyelid Injuries & Poisonings 1.02 0.873 – 1.18 0.84 204 2026 all phecode
870.2 Open wound of ear Injuries & Poisonings 0.938 0.787 – 1.12 0.475 144 1437 all phecode
870.3 Other open wound of head and face Injuries & Poisonings 0.952 0.898 – 1.01 0.0969 1346 13301 all phecode
870.4 Open wound of nose and sinus Injuries & Poisonings 1.03 0.892 – 1.2 0.656 207 2057 all phecode
870.5 Open wound of lip and mouth Injuries & Poisonings 1.09 0.964 – 1.24 0.164 275 2724 all phecode
870.6 Open wound of neck Injuries & Poisonings 1.01 0.878 – 1.17 0.871 214 2128 all phecode
870.8 Open wound of genital organs Injuries & Poisonings 1.16 0.971 – 1.39 0.102 144 1440 all phecode
871 Open wounds of extremities Injuries & Poisonings 1.03 0.989 – 1.06 0.173 3530 32903 all phecode
871.1 Open wound of hand except finger(s) Injuries & Poisonings 0.989 0.906 – 1.08 0.802 572 5701 all phecode
871.2 Open wound of finger(s) Injuries & Poisonings 0.979 0.916 – 1.05 0.531 984 9772 all phecode
871.3 Open wound of foot except toe(s) alone Injuries & Poisonings 1.03 0.935 – 1.13 0.573 490 4843 all phecode
871.4 Open wound of toe(s) Injuries & Poisonings 0.985 0.871 – 1.11 0.811 295 2921 all phecode
872 Traumatic amputation Injuries & Poisonings 1.04 0.946 – 1.13 0.448 551 5477 all phecode
874 Complication of amputation stump Injuries & Poisonings 1.21 1.03 – 1.43 0.0202 170 1697 all phecode
875 Non-healing surgical wound Injuries & Poisonings 1.01 0.929 – 1.11 0.761 572 5720 all phecode
876
Posttraumatic wound infection not elsewhere
Posttraumatic wound infection not elsewhere classified
 Injuries & Poisonings 1.11 1.04 – 1.2 0.00411 802 8003 all phecode
907 Injuries to the nervous system Injuries & Poisonings 1.06 0.996 – 1.14 0.0656 1010 10096 all phecode
910 Superficial injury, infected Injuries & Poisonings 1.1 0.907 – 1.33 0.339 119 1161 all phecode
911 Blister Injuries & Poisonings 1.1 0.976 – 1.25 0.116 302 2996 all phecode
912 Insect bite Injuries & Poisonings 0.968 0.88 – 1.06 0.498 492 4886 all phecode
913 Toxic effect of venom Injuries & Poisonings 0.968 0.863 – 1.09 0.582 337 3326 all phecode
916 Contusion Injuries & Poisonings 0.981 0.95 – 1.01 0.25 4296 38033 all phecode
930 Allergic reaction to food Injuries & Poisonings 1.02 0.946 – 1.1 0.593 763 7596 all phecode
931
Contact dermatitis and other eczema due to
Contact dermatitis and other eczema due to plants [except food]
 Dermatologic 0.987 0.913 – 1.07 0.753 714 7072 all phecode
938 Dermatitis due to solar radiation Dermatologic 0.96 0.932 – 0.989 0.00674 5567 29098 all phecode
938.1 Acute dermatitis due to solar radiation Dermatologic 1.02 0.881 – 1.17 0.826 217 2164 all phecode
938.2 Chronic dermatitis due to solar radiation Dermatologic 0.959 0.93 – 0.989 0.00716 5307 28656 all phecode
939
Atopic/contact dermatitis due to other or
Atopic/contact dermatitis due to other or unspecified
 Dermatologic 0.981 0.955 – 1.01 0.172 6704 32389 all phecode
939.1 Contact and allergic dermatitis of eyelid Dermatologic 0.94 0.75 – 1.18 0.592 91 870 all phecode
941 Adverse reaction to serum or vaccine Injuries & Poisonings 1.14 0.977 – 1.32 0.0964 188 1880 all phecode
942 Infusion and transfusion reaction Injuries & Poisonings 1.16 1.02 – 1.31 0.0247 269 2688 all phecode
946 Anaphylactic shock NOS Injuries & Poisonings 0.93 0.847 – 1.02 0.128 500 4940 all phecode
947 Urticaria Dermatologic 0.968 0.91 – 1.03 0.299 1177 11454 all phecode
949 Allergies, other Injuries & Poisonings 1 0.976 – 1.03 0.842 7251 32350 all phecode
952
Spinal cord injury without evidence of spinal
Spinal cord injury without evidence of spinal bone injury
 Injuries & Poisonings 1.08 0.986 – 1.19 0.0976 494 4940 all phecode
957 Injury to other and unspecified nerves Injuries & Poisonings 1.03 0.861 – 1.23 0.751 136 1352 all phecode
958
Certain early complications of trauma or
Certain early complications of trauma or procedure
 Injuries & Poisonings 1.06 0.999 – 1.13 0.0533 1217 12158 all phecode
958.1 Postoperative shock Injuries & Poisonings 1.15 0.974 – 1.35 0.101 169 1688 all phecode
958.2 Traumatic and surgical subcutaneous emphysema Injuries & Poisonings 0.827 0.677 – 1.01 0.0645 114 1140 all phecode
960 Poisoning by antibiotics Injuries & Poisonings 1.09 1.04 – 1.13 0.000154 2479 22087 all phecode
960.1
Adverse effects of antibacterials (not
Adverse effects of antibacterials (not penicillins)
 Injuries & Poisonings 1.07 0.955 – 1.2 0.246 342 3403 all phecode
960.2 Allergy/adverse effect of penicillin Injuries & Poisonings 1.09 1.04 – 1.15 0.00081 1636 16005 all phecode
961 Poisoning by other anti-infectives Injuries & Poisonings 1.07 0.981 – 1.18 0.122 528 5234 all phecode
961.1 Poisoning/allergy of sulfonamides Injuries & Poisonings 1.09 1.02 – 1.17 0.00712 1065 10347 all phecode
962 Poisoning by hormones and synthetic substitutes Injuries & Poisonings 1.08 1 – 1.16 0.0505 803 7976 all phecode
962.1
Adrenal cortical steroids causing adverse
Adrenal cortical steroids causing adverse effects in therapeutic use
 Injuries & Poisonings 1.12 1 – 1.25 0.0413 379 3782 all phecode
962.2
Insulins and antidiabetic agents causing
Insulins and antidiabetic agents causing adverse effects in therapeutic use
 Injuries & Poisonings 1.21 0.933 – 1.57 0.151 62 612 all phecode
962.3
Hormones and synthetic substitutes causing
Hormones and synthetic substitutes causing adverse effects in therapeutic use
 Injuries & Poisonings 1.01 0.915 – 1.11 0.908 478 4773 all phecode
963 Poisoning by primarily systemic agents Injuries & Poisonings 1 0.963 – 1.05 0.842 2533 24531 all phecode
963.1
Antineoplastic and immunosuppressive drugs
Antineoplastic and immunosuppressive drugs causing adverse effects
 Injuries & Poisonings 1 0.962 – 1.05 0.882 2469 24057 all phecode
964
Poisoning by agents primarily affecting blood
Poisoning by agents primarily affecting blood constituents
 Injuries & Poisonings 1.09 1.01 – 1.18 0.0316 743 7337 all phecode
964.1 Anticoagulants causing adverse effects Injuries & Poisonings 1.09 1.01 – 1.18 0.0289 712 7027 all phecode
965
Poisoning by analgesics, antipyretics, and
Poisoning by analgesics, antipyretics, and antirheumatics
 Injuries & Poisonings 1.01 0.942 – 1.09 0.754 864 8601 all phecode
965.1
Opiates and related narcotics causing adverse
Opiates and related narcotics causing adverse effects in therapeutic use
 Injuries & Poisonings 1.03 0.976 – 1.09 0.27 1469 14402 all phecode
965.3
Salicylates causing adverse effects in
Salicylates causing adverse effects in therapeutic use
 Injuries & Poisonings 1.04 0.862 – 1.25 0.695 119 1182 all phecode
966
Poisoning by anticonvulsants and
Poisoning by anticonvulsants and anti-Parkinsonism drugs
 Injuries & Poisonings 1.06 0.867 – 1.31 0.551 103 1006 all phecode
967
Adverse effects of sedatives or other central
Adverse effects of sedatives or other central nervous system depressants and anesthetics
 Injuries & Poisonings 1.01 0.95 – 1.07 0.79 1254 12464 all phecode
969 Poisoning by psychotropic agents Injuries & Poisonings 1.01 0.888 – 1.14 0.911 281 2797 all phecode
971
Poisoning by drugs primarily affecting the
Poisoning by drugs primarily affecting the autonomic nervous system
 Injuries & Poisonings 0.966 0.735 – 1.27 0.805 67 643 all phecode
972
Poisoning by agents primarily affecting the
Poisoning by agents primarily affecting the cardiovascular system
 Injuries & Poisonings 1.18 1.05 – 1.34 0.00711 288 2858 all phecode
972.1
Cardiac rhythm regulators causing adverse
Cardiac rhythm regulators causing adverse effects in therapeutic use
 Injuries & Poisonings 1 0.792 – 1.26 1 80 776 all phecode
972.6 Antihypertensive agents causing adverse effects Injuries & Poisonings 1.26 1.03 – 1.54 0.0248 104 1034 all phecode
974
Poisoning by water, mineral, and uric acid
Poisoning by water, mineral, and uric acid metabolism drugs
 Injuries & Poisonings 1.27 1.05 – 1.54 0.0136 113 1130 all phecode
975
Poisoning by agents primarily acting on the
Poisoning by agents primarily acting on the smooth and skeletal muscles and respiratory system
 Injuries & Poisonings 1.05 0.825 – 1.33 0.703 81 810 all phecode
976
Poisoning by agents primarily affecting skin &
Poisoning by agents primarily affecting skin & mucous membrane, ophthalmological, otorhinolaryngological, & dental drugs
 Injuries & Poisonings 1.13 0.871 – 1.47 0.355 71 703 all phecode
977 Personal history of allergy to medicinal agents Injuries & Poisonings 1.06 1 – 1.11 0.0315 1763 16599 all phecode
979 Adverse drug events and drug allergies Injuries & Poisonings 1.02 0.988 – 1.06 0.183 3448 30885 all phecode
980
Encounter for long-term (current) use of
Encounter for long-term (current) use of antibiotics
 Infectious Diseases 1.01 0.954 – 1.07 0.738 1391 13877 all phecode
985 Toxic effect of other metals Injuries & Poisonings 0.9 0.674 – 1.2 0.476 57 564 all phecode
989
Toxic effect of other substances, chiefly
Toxic effect of other substances, chiefly nonmedicinal as to source
 Injuries & Poisonings 1.01 0.843 – 1.22 0.897 129 1275 all phecode
990 Effects radiation NOS Injuries & Poisonings 1 0.97 – 1.04 0.828 3927 31223 all phecode
994 Sepsis and SIRS Injuries & Poisonings 1.03 0.987 – 1.08 0.162 2192 21710 all phecode
994.1 Systemic inflammatory response syndrome (SIRS) Injuries & Poisonings 1.01 0.893 – 1.14 0.867 291 2910 all phecode
994.2 Sepsis Injuries & Poisonings 1.03 0.986 – 1.08 0.18 2086 20666 all phecode
994.21 Septic shock Injuries & Poisonings 1.1 1.01 – 1.19 0.0295 627 6260 all phecode
008 Intestinal infection Infectious Diseases 1.09 1.02 – 1.17 0.0139 946 8151 exclusion phecode
008.5 Bacterial enteritis Infectious Diseases 1.16 1.05 – 1.29 0.00483 417 3348 exclusion phecode
008.52 Intestinal infection due to C. difficile Infectious Diseases 1.18 1.05 – 1.33 0.00422 333 2590 exclusion phecode
008.6 Viral Enteritis Infectious Diseases 1.04 0.911 – 1.19 0.547 254 2299 exclusion phecode
010 Tuberculosis Infectious Diseases 1.26 0.983 – 1.6 0.0679 72 579 exclusion phecode
031 Diseases due to other mycobacteria Infectious Diseases 1.4 0.953 – 2.06 0.0861 36 211 exclusion phecode
038 Septicemia Infectious Diseases 1.16 1.07 – 1.24 0.000125 859 5489 exclusion phecode
038.1 Gram negative septicemia Infectious Diseases 1.14 0.973 – 1.35 0.103 181 1149 exclusion phecode
038.2 Gram positive septicemia Infectious Diseases 1.29 1.01 – 1.64 0.0407 84 492 exclusion phecode
038.3 Bacteremia Infectious Diseases 1.16 1.04 – 1.3 0.00723 379 2492 exclusion phecode
041 Bacterial infection NOS Infectious Diseases 1.09 1.04 – 1.15 0.000818 1829 10344 exclusion phecode
041.1 Staphylococcus infections Infectious Diseases 1.15 1.05 – 1.26 0.00326 513 4030 exclusion phecode
041.11 Methicillin sensitive Staphylococcus aureus Infectious Diseases 1.19 1.05 – 1.34 0.00663 292 2120 exclusion phecode
041.12 Methicillin resistant Staphylococcus aureus Infectious Diseases 1.22 1.07 – 1.4 0.00349 229 1868 exclusion phecode
041.2 Streptococcus infection Infectious Diseases 1.12 1.02 – 1.23 0.0224 497 3806 exclusion phecode
041.21 Rheumatic fever / chorea Infectious Diseases 0.904 0.673 – 1.21 0.503 49 583 exclusion phecode
041.4 E. coli Infectious Diseases 1.22 1.09 – 1.37 0.000548 361 2752 exclusion phecode
041.8 H. pylori Infectious Diseases 0.974 0.759 – 1.25 0.834 76 686 exclusion phecode
041.9 Infection with drug-resistant microorganisms Infectious Diseases 1.32 1.08 – 1.6 0.00602 118 868 exclusion phecode
053 Herpes zoster Infectious Diseases 0.964 0.865 – 1.07 0.507 389 3645 exclusion phecode
053.1 Herpes zoster with nervous system complications Infectious Diseases 1.1 0.809 – 1.51 0.535 47 490 exclusion phecode
054 Herpes simplex Infectious Diseases 0.94 0.86 – 1.03 0.177 573 4848 exclusion phecode
070 Viral hepatitis Infectious Diseases 1.09 0.946 – 1.26 0.232 216 1915 exclusion phecode
070.1 Viral hepatitis A Infectious Diseases 1.3 0.786 – 2.14 0.308 17 173 exclusion phecode
070.2 Viral hepatitis B Infectious Diseases 0.968 0.742 – 1.26 0.813 66 491 exclusion phecode
070.3 Viral hepatitis C Infectious Diseases 1.11 0.932 – 1.33 0.239 133 1196 exclusion phecode
070.4 Chronic hepatitis Infectious Diseases 1.19 0.903 – 1.57 0.216 56 459 exclusion phecode
070.9 Hepatitis NOS Infectious Diseases 1.05 0.926 – 1.2 0.429 264 2528 exclusion phecode
071 Human immunodeficiency virus [HIV] disease Infectious Diseases 1.24 0.878 – 1.74 0.224 38 368 exclusion phecode
071.1 HIV infection, symptomatic Infectious Diseases 1.29 0.878 – 1.88 0.197 32 269 exclusion phecode
078 Viral warts & HPV Infectious Diseases 0.917 0.859 – 0.978 0.00865 1104 8387 exclusion phecode
079 Viral infection Infectious Diseases 0.984 0.936 – 1.03 0.523 2022 9425 exclusion phecode
079.1 Varicella infection Infectious Diseases 0.963 0.902 – 1.03 0.269 1041 8455 exclusion phecode
079.2 Infectious mononucleosis Infectious Diseases 0.992 0.805 – 1.22 0.943 101 976 exclusion phecode
079.9 Viremia, NOS Infectious Diseases 0.97 0.85 – 1.11 0.645 248 2464 exclusion phecode
080 Postoperative infection Infectious Diseases 1.13 1.05 – 1.22 0.00183 798 6866 exclusion phecode
081
Infection/inflammation of internal prosthetic
Infection/inflammation of internal prosthetic device; implant; and graft
 Infectious Diseases 1.15 1.04 – 1.26 0.00418 503 3937 exclusion phecode
090
Sexually transmitted infections (not HIV or
Sexually transmitted infections (not HIV or hepatitis)
 Infectious Diseases 1.06 0.942 – 1.19 0.345 345 3263 exclusion phecode
110 Dermatophytosis / Dermatomycosis Infectious Diseases 0.932 0.866 – 1 0.0642 831 7508 exclusion phecode
110.1 Dermatophytosis Infectious Diseases 0.951 0.879 – 1.03 0.219 736 6632 exclusion phecode
110.11 Dermatophytosis of nail Infectious Diseases 0.995 0.898 – 1.1 0.923 437 3789 exclusion phecode
110.12 Althete's foot Infectious Diseases 0.874 0.744 – 1.03 0.101 174 1776 exclusion phecode
110.13 Dermatophytosis of the body Infectious Diseases 0.949 0.82 – 1.1 0.481 201 2011 exclusion phecode
110.2 Dermatomycoses Infectious Diseases 0.837 0.691 – 1.01 0.0689 119 1190 exclusion phecode
112 Candidiasis Infectious Diseases 1.06 0.997 – 1.13 0.0628 1270 8911 exclusion phecode
112.3 Candidiasis of skin and nails Infectious Diseases 1.07 0.904 – 1.27 0.434 156 1829 exclusion phecode
117 Mycoses Infectious Diseases 1.16 0.998 – 1.35 0.0531 203 1613 exclusion phecode
117.1 Histoplasmosis Infectious Diseases 0.898 0.537 – 1.5 0.681 21 187 exclusion phecode
117.4 Aspergillosis Infectious Diseases 1.16 0.828 – 1.62 0.393 42 358 exclusion phecode
130 Spirochetal infection Infectious Diseases 1.07 0.822 – 1.4 0.61 63 441 exclusion phecode
130.1 Lyme disease Infectious Diseases 0.904 0.646 – 1.27 0.558 43 323 exclusion phecode
131 Protozoan infection Infectious Diseases 1.21 0.794 – 1.83 0.38 30 260 exclusion phecode
132 Infestation (lice, mites) Infectious Diseases 1.17 0.892 – 1.53 0.259 64 588 exclusion phecode
134 Helminthiases Infectious Diseases 1.16 0.785 – 1.73 0.448 31 216 exclusion phecode
134.1 Intestinal helminthiases Infectious Diseases 1.29 0.793 – 2.08 0.309 21 145 exclusion phecode
136 Other infectious and parasitic diseases Infectious Diseases 1.06 0.987 – 1.13 0.112 1009 8983 exclusion phecode
145 Cancer of mouth Neoplasms 1.01 0.896 – 1.14 0.841 275 3038 exclusion phecode
145.1 Cancer of lip Neoplasms 1.29 0.75 – 2.22 0.358 12 140 exclusion phecode
145.2 Cancer of tongue Neoplasms 1.08 0.894 – 1.31 0.423 124 1319 exclusion phecode
145.3 Cancer of major salivary glands Neoplasms 0.855 0.675 – 1.08 0.191 75 791 exclusion phecode
145.4 Cancer of the gums Neoplasms 0.982 0.667 – 1.44 0.926 25 293 exclusion phecode
145.5 Cancer of the mouth floor Neoplasms 1.04 0.735 – 1.48 0.813 34 416 exclusion phecode
149 Cancer of larynx, pharynx, nasal cavities Neoplasms 1.11 0.984 – 1.26 0.0896 276 2681 exclusion phecode
149.1 Cancer of oropharynx Neoplasms 1.2 0.944 – 1.53 0.135 76 689 exclusion phecode
149.2 Cancer of nasopharynx Neoplasms 1.03 0.702 – 1.51 0.883 28 262 exclusion phecode
149.3 Cancer of hypopharynx Neoplasms 0.675 0.419 – 1.09 0.107 20 158 exclusion phecode
149.4 Cancer of larynx Neoplasms 1.37 1.09 – 1.72 0.00654 81 816 exclusion phecode
149.5
Hx of malignant neoplasm of oral cavity and
Hx of malignant neoplasm of oral cavity and pharynx
 Neoplasms 1.01 0.84 – 1.21 0.929 126 1129 exclusion phecode
149.9 Cancer of of nasal cavities Neoplasms 0.98 0.706 – 1.36 0.902 39 503 exclusion phecode
150 Cancer of esophagus Neoplasms 1.16 0.971 – 1.39 0.101 156 821 exclusion phecode
151 Cancer of stomach Neoplasms 1.04 0.874 – 1.23 0.678 148 969 exclusion phecode
153 Colorectal cancer Neoplasms 1 0.894 – 1.12 0.978 340 3013 exclusion phecode
153.2 Colon cancer Neoplasms 0.997 0.878 – 1.13 0.963 270 2265 exclusion phecode
153.3
Malignant neoplasm of rectum, rectosigmoid
Malignant neoplasm of rectum, rectosigmoid junction, and anus
 Neoplasms 1 0.863 – 1.16 0.995 207 1771 exclusion phecode
155 Cancer of liver and intrahepatic bile duct Neoplasms 1.1 0.92 – 1.32 0.289 129 1113 exclusion phecode
155.1 Malignant neoplasm of liver, primary Neoplasms 1.16 0.926 – 1.45 0.2 89 722 exclusion phecode
157 Pancreatic cancer Neoplasms 1.1 0.915 – 1.31 0.317 134 1038 exclusion phecode
158
Neoplasm of unspecified nature of digestive
Neoplasm of unspecified nature of digestive system
 Neoplasms 1.06 0.95 – 1.18 0.3 372 3386 exclusion phecode
159
Malignant neoplasm of other and ill-defined
Malignant neoplasm of other and ill-defined sites within the digestive organs and peritoneum
 Neoplasms 1.05 0.956 – 1.16 0.29 470 3774 exclusion phecode
159.2
Malignant neoplasm of small intestine
Malignant neoplasm of small intestine, including duodenum
 Neoplasms 0.995 0.736 – 1.35 0.976 49 476 exclusion phecode
159.3
Malignant neoplasm of gallbladder and
Malignant neoplasm of gallbladder and extrahepatic bile ducts
 Neoplasms 1.01 0.735 – 1.39 0.943 49 300 exclusion phecode
159.4
Malignant neoplasm of retroperitoneum and
Malignant neoplasm of retroperitoneum and peritoneum
 Neoplasms 1 0.802 – 1.26 0.977 93 705 exclusion phecode
164 Cancer of intrathoracic organs Neoplasms 0.973 0.711 – 1.33 0.865 48 294 exclusion phecode
165 Cancer within the respiratory system Neoplasms 1.03 0.915 – 1.15 0.663 350 2628 exclusion phecode
165.1 Cancer of bronchus; lung Neoplasms 1.03 0.91 – 1.17 0.632 289 2052 exclusion phecode
170 Cancer of bone and connective tissue Neoplasms 1.02 0.919 – 1.13 0.741 426 3932 exclusion phecode
170.1 Bone cancer Neoplasms 1.12 0.96 – 1.31 0.149 183 1665 exclusion phecode
170.2 Cancer of connective tissue Neoplasms 0.944 0.841 – 1.06 0.331 322 2816 exclusion phecode
172 Skin cancer Neoplasms 0.944 0.893 – 0.998 0.0408 1620 9111 exclusion phecode
172.1 Melanomas of skin, dx or hx Neoplasms 0.927 0.866 – 0.993 0.0307 972 7834 exclusion phecode
172.11 Melanomas of skin Neoplasms 0.975 0.891 – 1.07 0.573 530 6234 exclusion phecode
172.2 Other non-epithelial cancer of skin Neoplasms 0.945 0.889 – 1 0.0654 1316 7859 exclusion phecode
172.21 Basal cell carcinoma Neoplasms 0.922 0.849 – 1 0.055 650 5535 exclusion phecode
172.22 Squamous cell carcinoma Neoplasms 0.995 0.896 – 1.1 0.919 402 3581 exclusion phecode
172.3 Carcinoma in situ of skin Neoplasms 0.845 0.738 – 0.967 0.0143 238 2475 exclusion phecode
173 Neoplasm of uncertain behavior of skin Neoplasms 0.887 0.803 – 0.98 0.0187 449 4788 exclusion phecode
174 Breast cancer Neoplasms 0.931 0.864 – 1 0.0562 918 4932 exclusion phecode
174.1 Breast cancer [female] Neoplasms 0.928 0.861 – 1 0.0546 873 4758 exclusion phecode
174.11 Malignant neoplasm of female breast Neoplasms 0.928 0.86 – 1 0.0549 854 4725 exclusion phecode
174.3 Neoplasm of uncertain behavior of breast Neoplasms 0.862 0.668 – 1.11 0.254 72 622 exclusion phecode
175 Acquired absence of breast Neoplasms 0.929 0.824 – 1.05 0.228 322 2794 exclusion phecode
180 Cervical cancer and dysplasia Neoplasms 0.946 0.866 – 1.03 0.216 611 4514 exclusion phecode
180.1 Cervical cancer Neoplasms 0.977 0.834 – 1.14 0.768 182 1626 exclusion phecode
180.3
Cervical intraepithelial neoplasia [CIN]
Cervical intraepithelial neoplasia [CIN] [Cervical dysplasia]
 Neoplasms 0.916 0.831 – 1.01 0.0779 489 3794 exclusion phecode
182 Malignant neoplasm of uterus Neoplasms 0.985 0.84 – 1.16 0.854 172 1953 exclusion phecode
184 Cancer of other female genital organs Neoplasms 0.995 0.89 – 1.11 0.934 359 3328 exclusion phecode
184.1
Malignant neoplasm of ovary and other uterine
Malignant neoplasm of ovary and other uterine adnexa
 Neoplasms 0.999 0.857 – 1.16 0.986 186 1597 exclusion phecode
184.11 Malignant neoplasm of ovary Neoplasms 1.03 0.864 – 1.22 0.767 147 1267 exclusion phecode
184.2
Cancer of other female genital organs
Cancer of other female genital organs (excluding uterus and ovary)
 Neoplasms 1.1 0.936 – 1.3 0.238 169 1695 exclusion phecode
185 Cancer of prostate Neoplasms 0.912 0.814 – 1.02 0.112 387 1924 exclusion phecode
187 Cancer of other male genital organs Neoplasms 0.918 0.715 – 1.18 0.5 62 683 exclusion phecode
187.1
Malignant neoplasm of unspecified male genital
Malignant neoplasm of unspecified male genital organ
 Neoplasms 0.907 0.576 – 1.43 0.673 22 205 exclusion phecode
187.2 Malignant neoplasm of testis Neoplasms 1.08 0.756 – 1.54 0.674 33 378 exclusion phecode
187.8
Neoplasm of uncertain behavior of male genital
Neoplasm of uncertain behavior of male genital organs
 Neoplasms 0.887 0.46 – 1.71 0.722 10 100 exclusion phecode
189
Cancer of urinary organs (incl. kidney and
Cancer of urinary organs (incl. kidney and bladder)
 Neoplasms 1.12 1.03 – 1.23 0.012 538 4911 exclusion phecode
189.1 Cancer of kidney and renal pelvis Neoplasms 1.17 1.03 – 1.32 0.0171 271 2928 exclusion phecode
189.11 Malignant neoplasm of kidney, except pelvis Neoplasms 1.15 1 – 1.32 0.0463 228 2540 exclusion phecode
189.12 Malignant neoplasm of renal pelvis Neoplasms 0.99 0.701 – 1.4 0.953 38 429 exclusion phecode
189.2 Cancer of bladder Neoplasms 1.05 0.937 – 1.19 0.377 304 2895 exclusion phecode
189.21 Malignant neoplasm of bladder Neoplasms 1.06 0.935 – 1.2 0.367 277 2657 exclusion phecode
189.4 Malignant neoplasm of other urinary organs Neoplasms 0.998 0.827 – 1.21 0.987 119 1128 exclusion phecode
190 Cancer of eye Neoplasms 1.13 0.762 – 1.66 0.551 28 276 exclusion phecode
191
Manlignant and unknown neoplasms of brain and
Manlignant and unknown neoplasms of brain and nervous system
 Neoplasms 1.09 0.96 – 1.24 0.181 282 2847 exclusion phecode
191.1 Cancer of brain and nervous system Neoplasms 1.12 0.967 – 1.3 0.129 198 1864 exclusion phecode
191.11 Cancer of brain Neoplasms 1.13 0.959 – 1.32 0.148 171 1651 exclusion phecode
193 Thyroid cancer Neoplasms 1.05 0.904 – 1.23 0.502 193 2880 exclusion phecode
194 Cancer of other endocrine glands Neoplasms 1.04 0.875 – 1.23 0.665 159 1685 exclusion phecode
195 Cancer, suspected or other Neoplasms 1.01 0.967 – 1.05 0.677 3794 7948 exclusion phecode
195.1 Malignant neoplasm, other Neoplasms 1.01 0.966 – 1.05 0.699 3724 7943 exclusion phecode
195.3 Malignant neoplasm of head, face, and neck Neoplasms 1.08 0.947 – 1.24 0.242 231 2037 exclusion phecode
196 Radiotherapy Neoplasms 1.04 0.951 – 1.13 0.398 585 4280 exclusion phecode
197 Chemotherapy Neoplasms 1.01 0.95 – 1.07 0.794 1436 6896 exclusion phecode
198 Secondary malignant neoplasm Neoplasms 1.04 0.978 – 1.1 0.215 1393 6811 exclusion phecode
198.1 Secondary malignancy of lymph nodes Neoplasms 0.992 0.922 – 1.07 0.825 878 6020 exclusion phecode
198.2 Secondary malignancy of respiratory organs Neoplasms 1.06 0.938 – 1.19 0.36 297 2432 exclusion phecode
198.3
Secondary malignant neoplasm of digestive
Secondary malignant neoplasm of digestive systems
 Neoplasms 0.973 0.849 – 1.11 0.692 247 1985 exclusion phecode
198.4 Secondary malignant neoplasm of liver Neoplasms 1.1 0.954 – 1.27 0.191 221 1762 exclusion phecode
198.5 Secondary malignancy of brain/spine Neoplasms 0.943 0.797 – 1.12 0.493 166 1488 exclusion phecode
198.6 Secondary malignancy of bone Neoplasms 1.09 0.949 – 1.25 0.224 240 1852 exclusion phecode
198.7 Secondary malignant neoplasm of skin Neoplasms 0.953 0.773 – 1.17 0.65 99 713 exclusion phecode
199 Neoplasm of uncertain behavior Neoplasms 1.02 0.96 – 1.08 0.53 1347 7743 exclusion phecode
199.4 Neurofibromatosis Neoplasms 1.11 0.744 – 1.67 0.598 22 297 exclusion phecode
200 Myeloproliferative disease Neoplasms 1.06 0.948 – 1.19 0.303 326 2629 exclusion phecode
200.1 Polycythemia vera Neoplasms 0.923 0.684 – 1.25 0.603 47 440 exclusion phecode
201 Hodgkin's disease Neoplasms 1.21 0.938 – 1.57 0.14 68 458 exclusion phecode
202 Cancer of other lymphoid, histiocytic tissue Neoplasms 1.15 1.03 – 1.27 0.00907 431 3541 exclusion phecode
202.2 Non-Hodgkins lymphoma Neoplasms 1.13 1.01 – 1.26 0.0288 373 2996 exclusion phecode
202.21 Nodular lymphoma Neoplasms 1.1 0.941 – 1.28 0.239 194 1595 exclusion phecode
202.22 Reticulosarcoma Neoplasms 1.21 0.886 – 1.65 0.231 48 346 exclusion phecode
202.24 Large cell lymphoma Neoplasms 1.18 0.847 – 1.64 0.331 48 299 exclusion phecode
204 Leukemia Neoplasms 1.17 1 – 1.35 0.0442 186 1454 exclusion phecode
204.1 Lymphoid leukemia Neoplasms 0.979 0.764 – 1.25 0.863 64 480 exclusion phecode
204.11 Lymphoid leukemia, acute Neoplasms 1.06 0.717 – 1.58 0.756 24 199 exclusion phecode
204.12 Lymphoid leukemia, chronic Neoplasms 0.951 0.71 – 1.27 0.736 44 298 exclusion phecode
204.2 Myeloid leukemia Neoplasms 1.13 0.906 – 1.42 0.272 81 562 exclusion phecode
204.21 Myeloid leukemia, acute Neoplasms 1.17 0.841 – 1.62 0.354 37 315 exclusion phecode
204.22 Myeloid leukemia, chronic Neoplasms 1.25 0.828 – 1.89 0.288 21 130 exclusion phecode
204.4 Multiple myeloma Neoplasms 1.37 1.02 – 1.83 0.0351 52 416 exclusion phecode
208 Benign neoplasm of colon Neoplasms 0.958 0.915 – 1 0.0642 2518 9791 exclusion phecode
209 Neuroendocrine tumors Neoplasms 0.923 0.7 – 1.22 0.57 52 584 exclusion phecode
210 Benign neoplasm of lip, oral cavity, and pharynx Neoplasms 1.01 0.914 – 1.12 0.826 432 4954 exclusion phecode
211
Benign neoplasm of other parts of digestive
Benign neoplasm of other parts of digestive system
 Neoplasms 1.07 1.02 – 1.13 0.00381 2061 10051 exclusion phecode
212
Benign neoplasm of respiratory and
Benign neoplasm of respiratory and intrathoracic organs
 Neoplasms 1.11 1 – 1.22 0.0415 480 4540 exclusion phecode
213 Benign neoplasm of bone and articular cartilage Neoplasms 1.03 0.935 – 1.14 0.539 464 4459 exclusion phecode
214 Lipoma Neoplasms 0.906 0.811 – 1.01 0.0801 364 3749 exclusion phecode
214.1 Lipoma of skin and subcutaneous tissue Neoplasms 1.01 0.878 – 1.17 0.862 223 2368 exclusion phecode
215
Other benign neoplasm of connective and other
Other benign neoplasm of connective and other soft tissue
 Neoplasms 1.03 0.965 – 1.09 0.41 1191 10735 exclusion phecode
216 Benign neoplasm of skin Neoplasms 0.953 0.914 – 0.994 0.0263 3057 9668 exclusion phecode
216.1 Screening for malignant neoplasms of the skin Neoplasms 1.17 0.892 – 1.54 0.252 57 483 exclusion phecode
217 Vascular hamartomas and non-neoplastic nevi Neoplasms 0.862 0.78 – 0.952 0.00342 461 4206 exclusion phecode
217.1 Nevus, non-neoplastic Neoplasms 0.854 0.77 – 0.948 0.003 423 3867 exclusion phecode
218 Benign neoplasm of uterus Neoplasms 0.992 0.936 – 1.05 0.78 1573 5737 exclusion phecode
218.1 Uterine leiomyoma Neoplasms 0.983 0.901 – 1.07 0.71 598 5233 exclusion phecode
218.2 Other benign neoplasm of uterus Neoplasms 1 0.939 – 1.06 0.999 1302 5661 exclusion phecode
220 Benign neoplasm of ovary Neoplasms 1.12 0.993 – 1.26 0.0665 333 3027 exclusion phecode
221 Benign neoplasm of other female genital organs Neoplasms 1.02 0.949 – 1.11 0.531 824 4996 exclusion phecode
222 Benign neoplasm of male genital organs Neoplasms 0.903 0.774 – 1.05 0.191 172 1980 exclusion phecode
223
Benign neoplasm of kidney and other urinary
Benign neoplasm of kidney and other urinary organs
 Neoplasms 1.02 0.917 – 1.13 0.721 385 3388 exclusion phecode
224 Benign neoplasm of eye Neoplasms 0.969 0.806 – 1.17 0.741 138 1443 exclusion phecode
224.1 Benign neoplasm of eye, uveal Neoplasms 1.03 0.84 – 1.27 0.772 113 1157 exclusion phecode
225
Benign neoplasm of brain and other parts of
Benign neoplasm of brain and other parts of nervous system
 Neoplasms 1.06 0.938 – 1.2 0.345 287 3234 exclusion phecode
225.1
Benign neoplasm of brain, cranial nerves
Benign neoplasm of brain, cranial nerves, meninges
 Neoplasms 1.09 0.943 – 1.26 0.24 204 2517 exclusion phecode
225.2 Benign neoplasm of spinal cord, meninges Neoplasms 1.05 0.836 – 1.31 0.695 88 798 exclusion phecode
226 Benign neoplasm of thyroid glands Neoplasms 1.08 0.942 – 1.24 0.27 240 3889 exclusion phecode
227
Benign neoplasm of other endocrine glands and
Benign neoplasm of other endocrine glands and related structures
 Neoplasms 0.997 0.881 – 1.13 0.958 275 4589 exclusion phecode
227.1 Benign neoplasm of adrenal gland Neoplasms 1.05 0.858 – 1.29 0.634 105 1199 exclusion phecode
227.2 Benign neoplasm of parathyroid gland Neoplasms 0.958 0.769 – 1.19 0.701 86 2153 exclusion phecode
227.3
Benign neoplasm of pituitary gland and
Benign neoplasm of pituitary gland and craniopharyngeal duct (pouch)
 Neoplasms 0.923 0.738 – 1.15 0.481 82 1215 exclusion phecode
228 Hemangioma and lymphangioma, any site Neoplasms 0.901 0.823 – 0.988 0.0259 537 5072 exclusion phecode
228.1 Hemangioma of skin and subcutaneous tissue Neoplasms 0.88 0.783 – 0.99 0.0329 317 3060 exclusion phecode
229 Benign neoplasm of unspecified sites Neoplasms 0.942 0.894 – 0.993 0.026 1762 10271 exclusion phecode
229.1 Benign neoplasm of lymph nodes Neoplasms 0.917 0.861 – 0.975 0.00583 1206 9457 exclusion phecode
240 Simple and unspecified goiter Endocrine/metabolic 1.07 0.943 – 1.21 0.294 286 3047 exclusion phecode
241 Nontoxic nodular goiter Endocrine/metabolic 1.04 0.962 – 1.13 0.311 703 6763 exclusion phecode
241.1 Nontoxic uninodular goiter Endocrine/metabolic 1.02 0.934 – 1.12 0.63 540 5890 exclusion phecode
241.2 Nontoxic multinodular goiter Endocrine/metabolic 1.08 0.948 – 1.23 0.245 257 3636 exclusion phecode
242 Thyrotoxicosis with or without goiter Endocrine/metabolic 1.09 0.98 – 1.22 0.111 358 3808 exclusion phecode
242.1 Graves' disease Endocrine/metabolic 1.18 0.998 – 1.41 0.0532 144 1543 exclusion phecode
242.2 Toxic multinodular goiter Endocrine/metabolic 1.1 0.76 – 1.59 0.619 30 346 exclusion phecode
242.3 Exophthalmos Endocrine/metabolic 0.94 0.72 – 1.23 0.651 59 798 exclusion phecode
242.31 Thyrotoxic exophthalmos Endocrine/metabolic 0.887 0.604 – 1.3 0.54 28 432 exclusion phecode
244 Hypothyroidism Endocrine/metabolic 1.09 1.04 – 1.15 0.00061 2135 9210 exclusion phecode
244.1 Secondary hypothyroidism Endocrine/metabolic 1.15 1.04 – 1.28 0.00846 395 4994 exclusion phecode
244.2 Acquired hypothyroidism Endocrine/metabolic 1.11 1 – 1.24 0.0473 399 3512 exclusion phecode
244.4 Hypothyroidism NOS Endocrine/metabolic 1.09 1.04 – 1.15 0.000685 2005 9099 exclusion phecode
245 Thyroiditis Endocrine/metabolic 1.04 0.915 – 1.19 0.525 265 2707 exclusion phecode
245.2 Chronic thyroiditis Endocrine/metabolic 1.09 0.942 – 1.27 0.244 210 2268 exclusion phecode
245.21 Chronic lymphocytic thyroiditis Endocrine/metabolic 1.08 0.935 – 1.26 0.286 208 2257 exclusion phecode
246 Other disorders of thyroid Endocrine/metabolic 1.07 1.01 – 1.13 0.0208 1535 8519 exclusion phecode
246.2 Thyroid cyst Endocrine/metabolic 1.07 0.725 – 1.58 0.736 27 245 exclusion phecode
246.7 Abnormal results of function study of thyroid Endocrine/metabolic 1.06 0.924 – 1.21 0.415 253 2521 exclusion phecode
249 Secondary diabetes mellitus Endocrine/metabolic 1.33 1.14 – 1.57 0.000388 200 2060 exclusion phecode
250 Diabetes mellitus Endocrine/metabolic 1.12 1.07 – 1.18 4.17e-06 2645 9884 exclusion phecode
250.1 Type 1 diabetes Endocrine/metabolic 1.14 0.992 – 1.32 0.0639 485 3068 exclusion phecode
250.11 Type 1 diabetes with ketoacidosis Endocrine/metabolic 1.27 0.903 – 1.8 0.169 90 317 exclusion phecode
250.12 Type 1 diabetes with renal manifestations Endocrine/metabolic 1.35 1 – 1.81 0.0482 80 719 exclusion phecode
250.13 Type 1 diabetes with ophthalmic manifestations Endocrine/metabolic 1.32 1.01 – 1.71 0.0417 133 813 exclusion phecode
250.14 Type 1 diabetes with neurological manifestations Endocrine/metabolic 1.36 1.04 – 1.79 0.0267 108 722 exclusion phecode
250.15
Diabetes type 1 with peripheral circulatory
Diabetes type 1 with peripheral circulatory disorders
 Endocrine/metabolic 2.07 1.16 – 3.68 0.0139 23 213 exclusion phecode
250.2 Type 2 diabetes Endocrine/metabolic 1.21 1.14 – 1.28 4.91e-10 1705 8843 exclusion phecode
250.21 Type 2 diabetes with ketoacidosis Endocrine/metabolic 1.45 1.06 – 1.98 0.0208 77 388 exclusion phecode
250.22 Type 2 diabetes with renal manifestations Endocrine/metabolic 1.54 1.34 – 1.77 1.22e-09 278 2907 exclusion phecode
250.23 Type 2 diabetes with ophthalmic manifestations Endocrine/metabolic 1.3 1.09 – 1.55 0.00408 199 2189 exclusion phecode
250.24 Type 2 diabetes with neurological manifestations Endocrine/metabolic 1.42 1.25 – 1.61 5.71e-08 363 3815 exclusion phecode
250.25
Diabetes type 2 with peripheral circulatory
Diabetes type 2 with peripheral circulatory disorders
 Endocrine/metabolic 1.74 1.44 – 2.11 1.68e-08 154 1220 exclusion phecode
250.3 Insulin pump user Endocrine/metabolic 1.34 1.2 – 1.49 8.46e-08 622 5325 exclusion phecode
250.4 Abnormal glucose Endocrine/metabolic 1.07 1.01 – 1.13 0.0267 1679 9394 exclusion phecode
250.41 Impaired fasting glucose Endocrine/metabolic 0.998 0.89 – 1.12 0.97 366 4225 exclusion phecode
250.42 Other abnormal glucose Endocrine/metabolic 1.07 1.01 – 1.14 0.0251 1486 9087 exclusion phecode
250.5 Glycosuria or Acetonuria Endocrine/metabolic 1.29 0.873 – 1.91 0.201 34 340 exclusion phecode
250.6 Polyneuropathy in diabetes Endocrine/metabolic 1.4 1.21 – 1.61 5.38e-06 301 3020 exclusion phecode
250.7 Diabetic retinopathy Endocrine/metabolic 1.12 0.966 – 1.3 0.133 229 2363 exclusion phecode
251 Other disorders of pancreatic internal secretion Endocrine/metabolic 1.09 0.965 – 1.23 0.165 312 2373 exclusion phecode
251.1 Hypoglycemia Endocrine/metabolic 1.1 0.976 – 1.24 0.115 375 2682 exclusion phecode
252 Disorders of parathyroid gland Endocrine/metabolic 1.1 0.982 – 1.22 0.101 350 5844 exclusion phecode
252.1 Hyperparathyroidism Endocrine/metabolic 1.11 0.983 – 1.24 0.0938 305 5239 exclusion phecode
252.2 Hypoparathyroidism Endocrine/metabolic 0.994 0.786 – 1.26 0.958 79 1372 exclusion phecode
253
Disorders of the pituitary gland and its
Disorders of the pituitary gland and its hypothalamic control
 Endocrine/metabolic 1.14 0.989 – 1.31 0.0704 225 2387 exclusion phecode
253.1 Pituitary hyperfunction Endocrine/metabolic 1.31 1.02 – 1.68 0.0311 74 845 exclusion phecode
253.11 Acromegaly and gigantism Endocrine/metabolic 1.51 0.866 – 2.64 0.146 12 216 exclusion phecode
253.2 Pituitary hypofunction Endocrine/metabolic 1.15 0.855 – 1.54 0.358 50 602 exclusion phecode
253.3 Diabetes insipidus Endocrine/metabolic 1.7 1.05 – 2.77 0.0323 15 247 exclusion phecode
253.4 Anterior pituitary disorders Endocrine/metabolic 1.26 0.847 – 1.88 0.252 28 277 exclusion phecode
253.7 Other disorders of neurohypophysis Endocrine/metabolic 0.942 0.622 – 1.43 0.779 25 246 exclusion phecode
255 Disorders of adrenal glands Endocrine/metabolic 1.04 0.934 – 1.15 0.5 394 4078 exclusion phecode
255.1 Adrenal hyperfunction Endocrine/metabolic 1.09 0.868 – 1.37 0.453 74 1198 exclusion phecode
255.11 Cushing's syndrome Endocrine/metabolic 1.03 0.766 – 1.38 0.86 42 659 exclusion phecode
255.12 Hyperaldosteronism Endocrine/metabolic 1.17 0.743 – 1.84 0.499 16 327 exclusion phecode
255.2 Adrenal hypofunction Endocrine/metabolic 1.14 0.978 – 1.32 0.0942 195 1814 exclusion phecode
255.21 Glucocorticoid deficiency Endocrine/metabolic 1.13 0.97 – 1.32 0.115 184 1744 exclusion phecode
256 Ovarian dysfunction Endocrine/metabolic 1.02 0.921 – 1.13 0.72 445 4842 exclusion phecode
256.4 Polycystic ovaries Endocrine/metabolic 1.02 0.902 – 1.16 0.715 276 3570 exclusion phecode
257 Testicular dysfunction Endocrine/metabolic 0.985 0.842 – 1.15 0.853 186 1704 exclusion phecode
257.1 Testicular hypofunction Endocrine/metabolic 1.01 0.856 – 1.18 0.949 178 1633 exclusion phecode
258 Iatrogenic endocrine disorders Endocrine/metabolic 1.82 1.05 – 3.18 0.0342 17 219 exclusion phecode
258.1 Postablative ovarian failure Endocrine/metabolic 1.12 0.829 – 1.51 0.463 50 463 exclusion phecode
259 Other endocrine disorders Endocrine/metabolic 1.05 0.923 – 1.19 0.463 274 3112 exclusion phecode
260 Protein-calorie malnutrition Endocrine/metabolic 1.2 1.13 – 1.29 6.26e-08 1057 6262 exclusion phecode
260.1 Cachexia Endocrine/metabolic 1.31 1.09 – 1.58 0.00396 148 596 exclusion phecode
260.2 severe protein-calorie malnutrition Endocrine/metabolic 1.14 1.04 – 1.24 0.00312 666 3739 exclusion phecode
260.22 Nutritional marasmus Endocrine/metabolic 1.2 1.04 – 1.37 0.0123 232 1413 exclusion phecode
260.3 Adult failure to thrive Endocrine/metabolic 1.24 1.08 – 1.43 0.00313 223 1252 exclusion phecode
260.6 Anorexia Endocrine/metabolic 0.99 0.877 – 1.12 0.864 299 2003 exclusion phecode
260.7 Polyphagia Endocrine/metabolic 0.781 0.512 – 1.19 0.25 22 252 exclusion phecode
261 Vitamin deficiency Endocrine/metabolic 1.03 0.979 – 1.08 0.264 2033 9510 exclusion phecode
261.1 Vitamin A deficiency Endocrine/metabolic 0.864 0.59 – 1.26 0.452 32 244 exclusion phecode
261.2 Vitamin B-complex deficiencies Endocrine/metabolic 0.992 0.864 – 1.14 0.913 236 2212 exclusion phecode
261.4 Vitamin D deficiency Endocrine/metabolic 1.03 0.975 – 1.08 0.324 1910 9518 exclusion phecode
261.41 Rickets or osteomalacia Endocrine/metabolic 1.44 0.79 – 2.63 0.233 12 139 exclusion phecode
262 Mineral deficiency NEC Endocrine/metabolic 1.01 0.901 – 1.13 0.879 357 3536 exclusion phecode
263 Other nutritional deficiency Endocrine/metabolic 1.08 0.977 – 1.19 0.132 456 4263 exclusion phecode
264 Lack of normal physiological development Endocrine/metabolic 1.2 0.964 – 1.49 0.103 109 768 exclusion phecode
264.2 Failure to thrive (childhood) Endocrine/metabolic 1.28 0.923 – 1.76 0.14 48 334 exclusion phecode
264.9
Lack of normal physiological development
Lack of normal physiological development, unspecified
 Endocrine/metabolic 1.01 0.731 – 1.4 0.952 48 327 exclusion phecode
269 Proteinuria Endocrine/metabolic 1.16 1.03 – 1.32 0.0168 287 3347 exclusion phecode
270
Disorders of protein plasma/amino-acid
Disorders of protein plasma/amino-acid transport and metabolism
 Endocrine/metabolic 1.2 1.05 – 1.36 0.00552 289 2336 exclusion phecode
270.1 Disturbances of amino-acid transport Endocrine/metabolic 1.36 1.02 – 1.81 0.0363 53 577 exclusion phecode
270.11
Disturbances of sulphur-bearing amino-acid
Disturbances of sulphur-bearing amino-acid metabolism
 Endocrine/metabolic 1.42 1.05 – 1.91 0.0222 50 466 exclusion phecode
270.2 Disorders of amino-acid metabolism Endocrine/metabolic 1.57 1.04 – 2.36 0.0308 24 247 exclusion phecode
270.3 Disorders of plasma protein metabolism Endocrine/metabolic 1.13 0.975 – 1.31 0.104 219 1591 exclusion phecode
270.32 Paraproteinemia Endocrine/metabolic 1.12 0.889 – 1.41 0.333 80 712 exclusion phecode
270.33 Amyloidosis Endocrine/metabolic 1.11 0.704 – 1.74 0.662 23 164 exclusion phecode
270.34 Alpha-1-antitrypsin deficiency Endocrine/metabolic 1.08 0.696 – 1.69 0.721 25 185 exclusion phecode
270.38
Other specified disorders of plasma protein
Other specified disorders of plasma protein metabolism
 Endocrine/metabolic 1.2 0.978 – 1.48 0.0798 122 741 exclusion phecode
271
Disorders of carbohydrate transport and
Disorders of carbohydrate transport and metabolism
 Endocrine/metabolic 0.958 0.879 – 1.05 0.338 580 7084 exclusion phecode
271.3
Intestinal disaccharidase deficiencies and
Intestinal disaccharidase deficiencies and disaccharide malabsorption
 Endocrine/metabolic 0.959 0.877 – 1.05 0.348 557 6858 exclusion phecode
271.9
Other disorders of carbohydrate transport and
Other disorders of carbohydrate transport and metabolism
 Endocrine/metabolic 0.748 0.505 – 1.11 0.146 27 299 exclusion phecode
272 Disorders of lipoid metabolism Endocrine/metabolic 1.11 1.06 – 1.16 6.79e-06 3646 8678 exclusion phecode
272.1 Hyperlipidemia Endocrine/metabolic 1.11 1.06 – 1.16 8.46e-06 3635 8673 exclusion phecode
272.11 Hypercholesterolemia Endocrine/metabolic 1.18 1.09 – 1.27 1.14e-05 1031 6216 exclusion phecode
272.12 Hyperglyceridemia Endocrine/metabolic 1.03 0.897 – 1.18 0.678 242 3080 exclusion phecode
272.13 Mixed hyperlipidemia Endocrine/metabolic 1.13 1.03 – 1.24 0.0101 604 4857 exclusion phecode
272.9 Unspecified disorder of lipoid metabolism Endocrine/metabolic 0.917 0.687 – 1.22 0.555 55 692 exclusion phecode
274 Gout and other crystal arthropathies Endocrine/metabolic 1.22 1.11 – 1.34 4.07e-05 489 4546 exclusion phecode
274.1 Gout Endocrine/metabolic 1.25 1.14 – 1.38 6.24e-06 458 4366 exclusion phecode
274.11 Gouty arthropathy Endocrine/metabolic 1.25 1.09 – 1.43 0.00101 237 2104 exclusion phecode
274.2 Crystal arthropathies Endocrine/metabolic 0.901 0.667 – 1.22 0.498 48 322 exclusion phecode
274.21 Chondrocalcinosis Endocrine/metabolic 0.919 0.669 – 1.26 0.604 42 298 exclusion phecode
275 Disorders of mineral metabolism Endocrine/metabolic 1.11 1.04 – 1.18 0.00202 1032 9586 exclusion phecode
275.1 Disorders of iron metabolism Hematopoietic 0.926 0.725 – 1.18 0.54 66 556 exclusion phecode
275.11 Hereditary hemochromatosis Hematopoietic 0.892 0.614 – 1.3 0.55 25 259 exclusion phecode
275.2 Disorders of copper metabolism Endocrine/metabolic 0.755 0.456 – 1.25 0.274 23 185 exclusion phecode
275.3 Disorders of magnesium metabolism Endocrine/metabolic 1.33 1.18 – 1.5 2.84e-06 315 2817 exclusion phecode
275.5 Disorders of calcium/phosphorus metabolism Endocrine/metabolic 1.1 1.02 – 1.19 0.0136 777 7978 exclusion phecode
275.51 Hypocalcemia Endocrine/metabolic 1.13 0.982 – 1.31 0.0865 210 2384 exclusion phecode
275.53 Disorders of phosphorus metabolism Endocrine/metabolic 1.21 1.09 – 1.35 0.000415 381 3255 exclusion phecode
275.6 Hypercalcemia Endocrine/metabolic 1.07 0.937 – 1.21 0.333 264 3280 exclusion phecode
276
Disorders of fluid, electrolyte, and acid-base
Disorders of fluid, electrolyte, and acid-base balance
 Endocrine/metabolic 1.14 1.08 – 1.19 5.14e-08 2588 10057 exclusion phecode
276.1 Electrolyte imbalance Endocrine/metabolic 1.19 1.12 – 1.25 2.05e-09 1601 8864 exclusion phecode
276.11 Hyperosmolality and/or hypernatremia Endocrine/metabolic 1.41 1.19 – 1.67 9.66e-05 170 1046 exclusion phecode
276.12 Hyposmolality and/or hyponatremia Endocrine/metabolic 1.22 1.13 – 1.33 1.18e-06 702 4715 exclusion phecode
276.13 Hyperpotassemia Endocrine/metabolic 1.25 1.15 – 1.35 8.35e-08 709 5346 exclusion phecode
276.14 Hypopotassemia Endocrine/metabolic 1.28 1.18 – 1.4 1.03e-08 633 4977 exclusion phecode
276.4 Acid-base balance disorder Endocrine/metabolic 1.27 1.17 – 1.38 2.1e-08 667 4458 exclusion phecode
276.41 Acidosis Endocrine/metabolic 1.27 1.16 – 1.4 1.91e-07 557 3851 exclusion phecode
276.42 Alkalosis Endocrine/metabolic 1.1 0.937 – 1.3 0.239 190 958 exclusion phecode
276.5 Hypovolemia Endocrine/metabolic 1.12 1.06 – 1.19 0.000135 1419 9169 exclusion phecode
276.6 Fluid overload Endocrine/metabolic 1.44 1.3 – 1.59 5.64e-12 457 2575 exclusion phecode
276.8 Polydipsia Endocrine/metabolic 0.851 0.596 – 1.21 0.371 36 389 exclusion phecode
277 Other disorders of metabolism Endocrine/metabolic 1.06 0.991 – 1.13 0.092 1048 9852 exclusion phecode
277.2
Other disorders of purine and pyrimidine
Other disorders of purine and pyrimidine metabolism
 Endocrine/metabolic 1.32 1.03 – 1.69 0.0293 67 802 exclusion phecode
277.4 Disorders of bilirubin excretion Endocrine/metabolic 1.02 0.889 – 1.18 0.754 235 1678 exclusion phecode
277.5 Other disorders of lipoid metabolism Endocrine/metabolic 1.07 0.93 – 1.22 0.359 247 2484 exclusion phecode
277.51 Lipoprotein disorders Endocrine/metabolic 1.04 0.897 – 1.21 0.597 207 2019 exclusion phecode
277.7 Dysmetabolic syndrome X Endocrine/metabolic 0.879 0.745 – 1.04 0.127 157 2400 exclusion phecode
278 Overweight, obesity and other hyperalimentation Endocrine/metabolic 1.06 1.02 – 1.1 0.0026 4202 8627 exclusion phecode
278.1 Obesity Endocrine/metabolic 1.08 1.04 – 1.13 0.000135 3397 8620 exclusion phecode
278.11 Morbid obesity Endocrine/metabolic 1.13 1.07 – 1.2 2.18e-05 1517 8570 exclusion phecode
278.3 Localized adiposity Endocrine/metabolic 1.06 0.868 – 1.29 0.579 110 1131 exclusion phecode
278.4 Abnormal weight gain Endocrine/metabolic 1.07 0.983 – 1.16 0.124 693 6446 exclusion phecode
279 Disorders involving the immune mechanism Endocrine/metabolic 1.04 0.97 – 1.12 0.261 850 7915 exclusion phecode
279.1 Immunity deficiency Endocrine/metabolic 1.02 0.905 – 1.14 0.788 337 3145 exclusion phecode
279.11 Deficiency of humoral immunity Endocrine/metabolic 1.22 0.978 – 1.52 0.0782 89 854 exclusion phecode
279.2 Autoimmune disease NEC Endocrine/metabolic 0.909 0.792 – 1.04 0.174 240 2180 exclusion phecode
279.7 Other immunological findings Endocrine/metabolic 1.03 0.969 – 1.09 0.364 1329 9941 exclusion phecode
279.8
Other specified disorders involving the immune
Other specified disorders involving the immune mechanism
 Endocrine/metabolic 0.96 0.828 – 1.11 0.592 206 1841 exclusion phecode
280 Iron deficiency anemias Hematopoietic 1.15 1.08 – 1.22 3.5e-06 1442 8110 exclusion phecode
280.1
Iron deficiency anemias, unspecified or not due
Iron deficiency anemias, unspecified or not due to blood loss
 Hematopoietic 1.15 1.08 – 1.22 3.55e-06 1390 8068 exclusion phecode
280.2
Iron deficiency anemia secondary to blood loss
Iron deficiency anemia secondary to blood loss (chronic)
 Hematopoietic 1.19 1.09 – 1.3 0.000122 589 4183 exclusion phecode
281 Other deficiency anemia Hematopoietic 1.24 1.04 – 1.47 0.0141 159 1126 exclusion phecode
281.1 Megaloblastic anemia Hematopoietic 1.13 0.876 – 1.45 0.35 74 573 exclusion phecode
281.11 Pernicious anemia Hematopoietic 1.27 0.841 – 1.93 0.254 25 239 exclusion phecode
281.12 Other vitamin B12 deficiency anemia Hematopoietic 0.896 0.673 – 1.19 0.455 54 420 exclusion phecode
281.9 Deficiency anemias Hematopoietic 1.43 1.14 – 1.79 0.0018 93 584 exclusion phecode
282 Hereditary hemolytic anemias Hematopoietic 1.02 0.816 – 1.27 0.868 100 747 exclusion phecode
282.8 Other hemoglobinopathies Hematopoietic 1.05 0.799 – 1.38 0.72 65 482 exclusion phecode
282.9 Other hereditary hemolytic anemias Hematopoietic 0.998 0.731 – 1.36 0.988 51 407 exclusion phecode
283 Acquired hemolytic anemias Hematopoietic 1.32 0.97 – 1.8 0.0771 57 351 exclusion phecode
283.1 Autoimmune hemolytic anemias Hematopoietic 1.24 0.711 – 2.17 0.445 17 136 exclusion phecode
284 Aplastic anemia Hematopoietic 1.1 0.956 – 1.26 0.187 244 1551 exclusion phecode
284.1 Pancytopenia Hematopoietic 1.1 0.947 – 1.27 0.217 214 1378 exclusion phecode
285 Other anemias Hematopoietic 1.1 1.05 – 1.14 1.06e-05 3669 8751 exclusion phecode
285.1 Acute posthemorrhagic anemia Hematopoietic 1.1 1.03 – 1.17 0.0038 1142 6514 exclusion phecode
285.2 Anemia of chronic disease Hematopoietic 1.14 1.04 – 1.25 0.00373 576 4299 exclusion phecode
285.21 Anemia in chronic kidney disease Hematopoietic 1.48 1.26 – 1.75 2.33e-06 166 1817 exclusion phecode
285.22 Anemia in neoplastic disease Hematopoietic 0.95 0.828 – 1.09 0.466 248 1555 exclusion phecode
286 Coagulation defects Hematopoietic 1.19 1.12 – 1.26 5.67e-08 1231 8384 exclusion phecode
286.1 Congenital coagulation defects Hematopoietic 1.23 0.96 – 1.57 0.102 74 752 exclusion phecode
286.11 Von willebrand's disease Hematopoietic 1.07 0.693 – 1.64 0.772 24 247 exclusion phecode
286.12
Congenital deficiency of other clotting factors
Congenital deficiency of other clotting factors (including factor VII)
 Hematopoietic 1.13 0.801 – 1.59 0.491 40 395 exclusion phecode
286.2
Encounter for long-term (current) use of
Encounter for long-term (current) use of anticoagulants
 Hematopoietic 1.19 1.11 – 1.28 7.31e-07 1049 5399 exclusion phecode
286.3
Coagulation defects complicating pregnancy or
Coagulation defects complicating pregnancy or postpartum
 Hematopoietic 1.41 1.06 – 1.9 0.0201 52 527 exclusion phecode
286.4 Acquired coagulation factor deficiency Hematopoietic 1.16 0.923 – 1.46 0.203 97 500 exclusion phecode
286.5
Hemorrhagic disorder due to intrinsic
Hemorrhagic disorder due to intrinsic circulating anticoagulants
 Hematopoietic 1.14 0.802 – 1.61 0.473 41 248 exclusion phecode
286.6 Defibrination syndrome Hematopoietic 1.14 1.06 – 1.23 7e-04 812 6117 exclusion phecode
286.7 Other and unspecified coagulation defects Hematopoietic 1.15 1.07 – 1.23 6.82e-05 973 7152 exclusion phecode
286.8 Hypercoagulable state Hematopoietic 1.02 0.902 – 1.16 0.721 290 2319 exclusion phecode
286.81 Primary hypercoagulable state Hematopoietic 1 0.884 – 1.14 0.94 277 2255 exclusion phecode
286.9 Abnormal coagulation profile Hematopoietic 1.34 1.2 – 1.5 3.8e-07 380 2335 exclusion phecode
287 Purpura and other hemorrhagic conditions Hematopoietic 1.18 1.11 – 1.27 1.44e-06 1018 6489 exclusion phecode
287.1 Spontaneous ecchymoses Hematopoietic 1.4 1.09 – 1.78 0.00738 69 523 exclusion phecode
287.3 Thrombocytopenia Hematopoietic 1.18 1.1 – 1.26 6.83e-06 941 5846 exclusion phecode
287.31 Primary thrombocytopenia Hematopoietic 1.17 0.994 – 1.38 0.0584 174 1374 exclusion phecode
287.32 Secondary thrombocytopenia Hematopoietic 1.28 1.1 – 1.49 0.00184 195 1284 exclusion phecode
287.4 Qualitative platelet defects Hematopoietic 1.06 0.75 – 1.49 0.745 37 298 exclusion phecode
288 Diseases of white blood cells Hematopoietic 1.1 1.04 – 1.16 0.00147 1487 9729 exclusion phecode
288.1 Decreased white blood cell count Hematopoietic 1.04 0.95 – 1.14 0.392 555 4045 exclusion phecode
288.11 Neutropenia Hematopoietic 1.06 0.949 – 1.18 0.313 386 2768 exclusion phecode
288.2 Elevated white blood cell count Hematopoietic 1.1 1.03 – 1.16 0.00349 1234 9108 exclusion phecode
288.3 Eosinophilia Hematopoietic 0.946 0.731 – 1.23 0.677 69 520 exclusion phecode
289 Other diseases of blood and blood-forming organs Hematopoietic 1.12 1.02 – 1.23 0.0135 560 4595 exclusion phecode
289.3
Personal history of diseases of blood and
Personal history of diseases of blood and blood-forming organs
 Hematopoietic 1.08 0.953 – 1.22 0.232 300 2671 exclusion phecode
289.4 Lymphadenitis Hematopoietic 1.03 0.971 – 1.1 0.29 1163 9256 exclusion phecode
289.5 Diseases of spleen Hematopoietic 0.947 0.782 – 1.15 0.577 129 945 exclusion phecode
289.8 Polycythemia, secondary Hematopoietic 1.16 0.869 – 1.54 0.318 49 517 exclusion phecode
289.9 Abnormality of red blood cells Hematopoietic 1.21 0.991 – 1.48 0.0616 116 909 exclusion phecode
290
Delirium dementia and amnestic and other
Delirium dementia and amnestic and other cognitive disorders
 Mental Disorders 1.21 1.07 – 1.37 0.00227 296 2095 exclusion phecode
290.1 Dementias Mental Disorders 1.11 0.893 – 1.37 0.355 92 785 exclusion phecode
290.11 Alzheimer's disease Mental Disorders 0.801 0.498 – 1.29 0.361 19 209 exclusion phecode
290.12 Dementia with cerebral degenerations Mental Disorders 1.02 0.607 – 1.71 0.94 16 126 exclusion phecode
290.13 Senile dementia Mental Disorders 1.25 0.947 – 1.66 0.114 55 435 exclusion phecode
290.16 Vascular dementia Mental Disorders 2.39 1.11 – 5.17 0.0261 9 110 exclusion phecode
290.2 Delirium due to conditions classified elsewhere Mental Disorders 1.25 1.08 – 1.46 0.00312 201 1391 exclusion phecode
290.3
Other persistent mental disorders due to
Other persistent mental disorders due to conditions classified elsewhere
 Mental Disorders 1.06 0.911 – 1.23 0.447 196 1856 exclusion phecode
291
Other specified nonpsychotic and/or transient
Other specified nonpsychotic and/or transient mental disorders
 Mental Disorders 1.09 1.01 – 1.18 0.0247 746 6631 exclusion phecode
291.1
Transient mental disorders due to conditions
Transient mental disorders due to conditions classified elsewhere
 Mental Disorders 1 0.801 – 1.26 0.976 86 789 exclusion phecode
291.4
Specific nonpsychotic mental disorders due to
Specific nonpsychotic mental disorders due to brain damage
 Mental Disorders 1.06 0.882 – 1.28 0.527 139 1263 exclusion phecode
291.8 Alteration of consciousness Mental Disorders 1.08 0.988 – 1.18 0.0899 563 5008 exclusion phecode
292 Neurological disorders Mental Disorders 1.09 1.03 – 1.16 0.00212 1477 10442 exclusion phecode
292.1 Aphasia/speech disturbance Mental Disorders 1.12 1.01 – 1.23 0.0244 485 4507 exclusion phecode
292.11 Aphasia Mental Disorders 1.27 1.08 – 1.5 0.00451 164 1507 exclusion phecode
292.12 Symbolic dysfunction Mental Disorders 1.49 1.06 – 2.1 0.0224 36 507 exclusion phecode
292.2 Mild cognitive impairment Mental Disorders 1.05 0.832 – 1.32 0.688 84 647 exclusion phecode
292.3 Memory loss Mental Disorders 1.03 0.928 – 1.14 0.609 434 4138 exclusion phecode
292.4 Altered mental status Mental Disorders 1.16 1.06 – 1.26 0.000745 643 4976 exclusion phecode
292.5 Transient alteration of awareness Mental Disorders 1.01 0.837 – 1.23 0.892 120 1030 exclusion phecode
292.6 Hallucinations Mental Disorders 1.5 1.15 – 1.96 0.00305 66 520 exclusion phecode
293 Symptoms involving head and neck Mental Disorders 1.05 0.865 – 1.27 0.629 121 1202 exclusion phecode
293.1
Swelling, mass, or lump in head and neck
Swelling, mass, or lump in head and neck [Space-occupying lesion, intracranial NOS]
 Mental Disorders 1.01 0.948 – 1.08 0.738 1095 10433 exclusion phecode
295 Schizophrenia and other psychotic disorders Mental Disorders 1.01 0.885 – 1.16 0.839 248 1910 exclusion phecode
295.1 Schizophrenia Mental Disorders 0.962 0.703 – 1.32 0.811 42 436 exclusion phecode
295.2 Paranoid disorders Mental Disorders 1.37 0.923 – 2.03 0.118 30 255 exclusion phecode
295.3 Psychosis Mental Disorders 1.04 0.892 – 1.22 0.606 198 1529 exclusion phecode
296 Mood disorders Mental Disorders 1.05 1 – 1.09 0.0285 4648 5553 exclusion phecode
296.1 Bipolar Mental Disorders 1.06 0.956 – 1.17 0.281 451 3697 exclusion phecode
296.2 Depression Mental Disorders 1.05 1 – 1.09 0.0359 4507 5550 exclusion phecode
296.22 Major depressive disorder Mental Disorders 1.04 0.999 – 1.09 0.0544 4189 5551 exclusion phecode
297 Suicidal ideation or attempt Mental Disorders 1.09 0.968 – 1.23 0.154 354 2946 exclusion phecode
297.1 Suicidal ideation Mental Disorders 1.1 0.964 – 1.25 0.156 294 2383 exclusion phecode
297.2 Suicide or self-inflicted injury Mental Disorders 1.16 0.942 – 1.42 0.163 114 967 exclusion phecode
300 Anxiety disorders Mental Disorders 1.02 0.976 – 1.06 0.44 4814 5550 exclusion phecode
300.1 Anxiety disorder Mental Disorders 1.02 0.976 – 1.06 0.428 4556 5552 exclusion phecode
300.11 Generalized anxiety disorder Mental Disorders 1.03 0.975 – 1.09 0.285 1803 5462 exclusion phecode
300.12 Agorophobia, social phobia, and panic disorder Mental Disorders 1.03 0.93 – 1.15 0.543 467 3721 exclusion phecode
300.13 Phobia Mental Disorders 1.03 0.909 – 1.18 0.616 306 2894 exclusion phecode
300.3 Obsessive-compulsive disorders Mental Disorders 0.96 0.784 – 1.18 0.697 112 1087 exclusion phecode
300.4 Dysthymic disorder Mental Disorders 0.961 0.889 – 1.04 0.32 796 4664 exclusion phecode
300.8 Acute reaction to stress Mental Disorders 1 0.845 – 1.19 0.977 158 1471 exclusion phecode
300.9 Posttraumatic stress disorder Mental Disorders 1.02 0.9 – 1.16 0.743 297 2710 exclusion phecode
301 Personality disorders Mental Disorders 1.11 0.95 – 1.3 0.189 184 1671 exclusion phecode
301.2 Antisocial/borderline personality disorder Mental Disorders 0.942 0.762 – 1.16 0.582 104 927 exclusion phecode
302 Sexual and gender identity disorders Mental Disorders 0.963 0.885 – 1.05 0.377 702 3343 exclusion phecode
302.1 Decreased libido Mental Disorders 0.842 0.695 – 1.02 0.0796 130 1124 exclusion phecode
303 Psychogenic and somatoform disorders Mental Disorders 0.952 0.898 – 1.01 0.0991 1651 5340 exclusion phecode
303.1 Dissociative disorder Mental Disorders 0.871 0.656 – 1.16 0.342 53 541 exclusion phecode
303.3 Psychogenic disorder Mental Disorders 0.943 0.888 – 1 0.0542 1545 5309 exclusion phecode
303.31
Gastrointestinal malfunction arising from
Gastrointestinal malfunction arising from mental factors
 Mental Disorders 0.871 0.727 – 1.04 0.132 134 1358 exclusion phecode
303.4 Somatoform disorder Mental Disorders 0.996 0.894 – 1.11 0.936 394 3607 exclusion phecode
304 Adjustment reaction Mental Disorders 0.987 0.924 – 1.05 0.701 1136 5454 exclusion phecode
305.2 Eating disorder Mental Disorders 0.973 0.851 – 1.11 0.685 255 2912 exclusion phecode
306 Other mental disorder Mental Disorders 0.965 0.885 – 1.05 0.413 643 4267 exclusion phecode
306.1 Mental disorders durring/after pregnancy Mental Disorders 0.972 0.862 – 1.1 0.646 344 1818 exclusion phecode
306.9 Tension headache Mental Disorders 0.91 0.8 – 1.03 0.149 267 2524 exclusion phecode
312 Conduct disorders Mental Disorders 0.921 0.728 – 1.17 0.496 82 728 exclusion phecode
312.3 Impulse control disorder Mental Disorders 0.866 0.575 – 1.3 0.492 24 244 exclusion phecode
313 Pervasive developmental disorders Mental Disorders 0.932 0.854 – 1.02 0.115 600 5151 exclusion phecode
313.1 Attention deficit hyperactivity disorder Mental Disorders 0.931 0.849 – 1.02 0.13 545 4684 exclusion phecode
313.2 Tics and stuttering Mental Disorders 0.707 0.423 – 1.18 0.186 20 229 exclusion phecode
313.3 Autism Mental Disorders 1.18 0.83 – 1.67 0.359 29 249 exclusion phecode
315 Develomental delays and disorders Mental Disorders 0.825 0.712 – 0.956 0.0106 210 1783 exclusion phecode
315.1 Learning disorder Mental Disorders 0.926 0.646 – 1.33 0.676 37 314 exclusion phecode
315.2 Speech and language disorder Mental Disorders 0.922 0.727 – 1.17 0.5 75 660 exclusion phecode
316 Substance addiction and disorders Mental Disorders 1.03 0.967 – 1.1 0.346 1105 8841 exclusion phecode
316.1 Polyneuropathy due to drugs Mental Disorders 0.881 0.749 – 1.04 0.123 179 1581 exclusion phecode
317 Alcohol-related disorders Mental Disorders 1.1 1.01 – 1.19 0.0271 672 5471 exclusion phecode
317.1 Alcoholism Mental Disorders 1.12 1.02 – 1.23 0.0139 544 4532 exclusion phecode
317.11 Alcoholic liver damage Mental Disorders 1.28 1.07 – 1.53 0.00757 139 869 exclusion phecode
318 Tobacco use disorder Mental Disorders 1.07 1.02 – 1.12 0.00716 2421 9429 exclusion phecode
320 Meningitis Neurological 1.03 0.848 – 1.24 0.793 113 1048 exclusion phecode
323 Encephalitis Neurological 0.88 0.658 – 1.18 0.387 54 465 exclusion phecode
323.8 Encephalitis, non-infectious Neurological 0.87 0.641 – 1.18 0.371 47 385 exclusion phecode
324 Other CNS infection and poliomyelitis Neurological 1.21 0.927 – 1.59 0.159 60 639 exclusion phecode
325
Phlebitis and thrombophlebitis of intracranial
Phlebitis and thrombophlebitis of intracranial venous sinuses
 Neurological 0.807 0.441 – 1.48 0.486 14 162 exclusion phecode
327 Sleep disorders Neurological 1.05 1 – 1.09 0.0289 3569 9210 exclusion phecode
327.1 Hypersomnia Neurological 0.935 0.853 – 1.03 0.157 522 5532 exclusion phecode
327.3 Sleep apnea Neurological 1.04 0.993 – 1.1 0.0921 2208 9054 exclusion phecode
327.31 Central/nonobstroctive sleep apnea Neurological 1.14 0.936 – 1.38 0.198 124 977 exclusion phecode
327.32 Obstructive sleep apnea Neurological 1.02 0.966 – 1.08 0.484 1763 8671 exclusion phecode
327.4 Insomnia Neurological 1.03 0.974 – 1.09 0.302 1603 9035 exclusion phecode
327.41 Organic or persistent insomnia Neurological 0.938 0.837 – 1.05 0.275 345 3285 exclusion phecode
327.5 Parasomnia Neurological 1.06 0.891 – 1.26 0.518 141 1441 exclusion phecode
327.6 Circadian rhythm sleep disorder Neurological 1.15 0.909 – 1.46 0.242 84 810 exclusion phecode
327.7 Sleep related movement disorders Neurological 1.1 0.997 – 1.22 0.0573 455 4570 exclusion phecode
327.71 Restless legs syndrome Neurological 1.12 1.01 – 1.25 0.0295 402 4065 exclusion phecode
327.72 Sleep related leg cramps Neurological 0.818 0.515 – 1.3 0.396 19 199 exclusion phecode
331 Other cerebral degenerations Neurological 1.11 0.923 – 1.32 0.275 144 1435 exclusion phecode
331.1 Hydrocephalus Neurological 1.07 0.817 – 1.41 0.608 64 721 exclusion phecode
331.9 Cerebral degeneration, unspecified Neurological 1.09 0.865 – 1.38 0.452 77 717 exclusion phecode
332 Parkinson's disease Neurological 1.01 0.793 – 1.3 0.909 78 702 exclusion phecode
333
Extrapyramidal disease and abnormal movement
Extrapyramidal disease and abnormal movement disorders
 Neurological 1.05 0.969 – 1.14 0.24 724 6789 exclusion phecode
333.1 Essential tremor Neurological 0.939 0.787 – 1.12 0.489 148 1417 exclusion phecode
333.2 Myoclonus Neurological 1.28 0.916 – 1.79 0.149 37 394 exclusion phecode
333.4 Torsion dystonia Neurological 1.05 0.847 – 1.3 0.655 100 908 exclusion phecode
333.8 Other degenerative diseases of the basal ganglia Neurological 1.16 0.73 – 1.85 0.525 25 159 exclusion phecode
334 Degenerative disease of the spinal cord Neurological 1.24 1.08 – 1.41 0.00177 251 2507 exclusion phecode
334.1 Spinocerebellar disease Neurological 0.826 0.466 – 1.46 0.512 16 178 exclusion phecode
334.2 Anterior horn cell disease Neurological 1.6 1.11 – 2.3 0.0121 31 238 exclusion phecode
334.21 Amyotrophic Lateral Sclerosis Neurological 1.63 1.02 – 2.61 0.0421 17 135 exclusion phecode
335 Multiple sclerosis Neurological 1.07 0.886 – 1.28 0.499 126 1149 exclusion phecode
337 Disorders of the autonomic nervous system Neurological 1.06 0.92 – 1.22 0.416 212 1898 exclusion phecode
337.1 Peripheral autonomic neuropathy Neurological 1.11 0.865 – 1.43 0.406 72 655 exclusion phecode
338 Pain Neurological 1.01 0.976 – 1.05 0.505 5720 7111 exclusion phecode
338.1 Acute pain Neurological 1.02 0.982 – 1.06 0.29 4412 7071 exclusion phecode
338.2 Chronic pain Neurological 0.998 0.955 – 1.04 0.937 2996 7086 exclusion phecode
339 Other headache syndromes Neurological 0.983 0.941 – 1.03 0.44 2928 8967 exclusion phecode
340 Migraine Neurological 1.02 0.967 – 1.07 0.546 2324 8300 exclusion phecode
340.1 Migrain with aura Neurological 1.01 0.95 – 1.08 0.707 1221 6970 exclusion phecode
341
Other demyelinating diseases of central nervous
Other demyelinating diseases of central nervous system
 Neurological 0.991 0.723 – 1.36 0.953 44 382 exclusion phecode
342 Hemiplegia Neurological 1.19 0.978 – 1.45 0.0827 113 1089 exclusion phecode
343 Infantile cerebral palsy Neurological 1.07 0.746 – 1.54 0.707 32 327 exclusion phecode
344 Other paralytic syndromes Neurological 1.19 1.02 – 1.39 0.03 194 1653 exclusion phecode
345 Epilepsy, recurrent seizures, convulsions Neurological 1.1 1.02 – 1.19 0.00982 800 7274 exclusion phecode
345.1 Epilepsy Neurological 1.1 0.959 – 1.26 0.175 257 2159 exclusion phecode
345.11 Generalized convulsive epilepsy Neurological 1.11 0.872 – 1.41 0.402 83 732 exclusion phecode
345.12 Partial epilepsy Neurological 1.01 0.857 – 1.19 0.903 178 1517 exclusion phecode
345.3 Convulsions Neurological 1.09 1.01 – 1.18 0.0254 741 6885 exclusion phecode
346
Abnormal findings on study of brain and/or
Abnormal findings on study of brain and/or nervous system
 Neurological 0.772 0.564 – 1.06 0.105 48 433 exclusion phecode
346.1
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of skull and head
 Neurological 1.14 1.02 – 1.28 0.0173 373 3468 exclusion phecode
346.2
Nonspecific abnormal results of function study
Nonspecific abnormal results of function study of brain and central nervous system
 Neurological 1.1 0.754 – 1.6 0.624 31 285 exclusion phecode
346.3
Nonspecific abnormal findings in cerebrospinal
Nonspecific abnormal findings in cerebrospinal fluid
 Neurological 1.08 0.764 – 1.54 0.65 32 308 exclusion phecode
347 Cataplexy and narcolepsy Neurological 0.997 0.696 – 1.43 0.989 33 346 exclusion phecode
348 Other conditions of brain Neurological 1.18 1.07 – 1.3 0.00116 478 4727 exclusion phecode
348.2 Cerebral edema and compression of brain Neurological 1.09 0.949 – 1.26 0.218 230 2585 exclusion phecode
348.4 Cerebral cysts Neurological 1.08 0.835 – 1.4 0.547 67 717 exclusion phecode
348.7 Coma Neurological 1.34 1.02 – 1.76 0.036 59 551 exclusion phecode
348.8 Encephalopathy, not elsewhere classified Neurological 1.26 1.09 – 1.46 0.0019 214 1888 exclusion phecode
348.9 Other conditions of brain, NOS Neurological 1.02 0.937 – 1.12 0.598 577 6002 exclusion phecode
349
Other and unspecified disorders of the nervous
Other and unspecified disorders of the nervous system
 Neurological 1.09 0.956 – 1.24 0.194 262 2498 exclusion phecode
350 Abnormal movement Neurological 1.01 0.958 – 1.07 0.692 1662 10736 exclusion phecode
350.1 Abnormal involuntary movements Neurological 0.981 0.914 – 1.05 0.605 879 7829 exclusion phecode
350.2 Abnormality of gait Neurological 1.06 0.989 – 1.14 0.098 853 7330 exclusion phecode
350.3 Lack of coordination Neurological 0.93 0.82 – 1.06 0.261 275 2672 exclusion phecode
350.5 Abnormal reflex Neurological 0.875 0.643 – 1.19 0.397 46 473 exclusion phecode
350.6 Disturbances of sensation of smell and taste Neurological 1.09 0.913 – 1.31 0.33 137 1271 exclusion phecode
351 Other peripheral nerve disorders Neurological 0.977 0.927 – 1.03 0.381 1791 9677 exclusion phecode
352 Disorders of other cranial nerves Neurological 0.996 0.895 – 1.11 0.938 398 4523 exclusion phecode
352.1 Trigeminal nerve disorders [CN5] Neurological 0.922 0.77 – 1.1 0.378 141 1525 exclusion phecode
352.2 Facial nerve disorders [CN7] Neurological 0.969 0.828 – 1.13 0.699 183 2044 exclusion phecode
353 Nerve root and plexus disorders Neurological 0.993 0.929 – 1.06 0.844 1023 9096 exclusion phecode
353.1 Nerve plexus lesions Neurological 0.912 0.752 – 1.11 0.35 118 1196 exclusion phecode
353.2 Nerve root lesions Neurological 1.46 0.994 – 2.13 0.0535 30 301 exclusion phecode
355 Complex regional/central pain syndrome Neurological 0.979 0.828 – 1.16 0.807 155 1632 exclusion phecode
355.1 Chronic pain syndrome Neurological 1.18 1.04 – 1.34 0.0124 259 2519 exclusion phecode
356 Hereditary and idiopathic peripheral neuropathy Neurological 1.04 0.943 – 1.15 0.419 448 4646 exclusion phecode
357 Inflammatory and toxic neuropathy Neurological 1.01 0.931 – 1.09 0.86 738 6991 exclusion phecode
358 Myoneural disorders Neurological 0.988 0.875 – 1.11 0.839 295 2950 exclusion phecode
358.1 Myasthenia gravis Neurological 0.931 0.625 – 1.38 0.723 35 262 exclusion phecode
359 Muscular dystrophies and other myopathies Neurological 1.07 0.95 – 1.2 0.266 332 3005 exclusion phecode
359.1 Muscular dystrophies Neurological 1.14 0.721 – 1.79 0.582 22 158 exclusion phecode
359.2 Myopathy Neurological 1.06 0.938 – 1.19 0.358 316 2906 exclusion phecode
360 Disorders of the globe Sense Organs 1.09 0.733 – 1.63 0.661 27 285 exclusion phecode
360.2 Progressive myopia Sense Organs 0.897 0.515 – 1.56 0.7 16 155 exclusion phecode
361 Retinal detachments and defects Sense Organs 0.963 0.817 – 1.14 0.656 162 1498 exclusion phecode
361.1 Retinal detachment with retinal defect Sense Organs 1.04 0.815 – 1.34 0.731 72 631 exclusion phecode
362 Other retinal disorders Sense Organs 0.99 0.908 – 1.08 0.824 622 5139 exclusion phecode
362.2
Degeneration of macula and posterior pole of
Degeneration of macula and posterior pole of retina
 Sense Organs 0.935 0.831 – 1.05 0.26 329 3062 exclusion phecode
362.21 Macular degeneration, dry Sense Organs 0.906 0.686 – 1.2 0.486 63 542 exclusion phecode
362.22 Macular degeneration, wet Sense Organs 0.888 0.549 – 1.44 0.628 22 166 exclusion phecode
362.23 Cystoid macular degeneration of retina Sense Organs 1.09 0.83 – 1.42 0.55 65 723 exclusion phecode
362.26 Macular puckering of retina Sense Organs 1.06 0.887 – 1.27 0.509 129 1627 exclusion phecode
362.27 Drusen (degenerative) of retina Sense Organs 0.963 0.756 – 1.23 0.76 81 816 exclusion phecode
362.29 Macular degeneration (senile) of retina NOS Sense Organs 0.955 0.841 – 1.08 0.474 283 2684 exclusion phecode
362.3 Other nondiabetic retinopathy Sense Organs 1.07 0.901 – 1.28 0.431 146 1792 exclusion phecode
362.31 Separation of retinal layers Sense Organs 0.83 0.653 – 1.06 0.128 78 866 exclusion phecode
362.4 Retinal vascular changes and abnomalities Sense Organs 0.98 0.811 – 1.18 0.837 127 1152 exclusion phecode
362.6 Peripheral retinal degenerations Sense Organs 0.83 0.66 – 1.04 0.111 91 883 exclusion phecode
362.7 Hereditary retinal dystrophies Sense Organs 1.01 0.742 – 1.38 0.935 46 463 exclusion phecode
362.8 Retinal hemorrhage/ischemia Sense Organs 1.05 0.775 – 1.42 0.756 41 539 exclusion phecode
362.9 Retinal edema Sense Organs 1.43 1.01 – 2.02 0.0422 34 629 exclusion phecode
363
Chorioretinal inflammations, scars, and other
Chorioretinal inflammations, scars, and other disorders of choroid
 Sense Organs 0.95 0.777 – 1.16 0.617 107 1008 exclusion phecode
363.3 Chorioretinal scars Sense Organs 0.935 0.728 – 1.2 0.6 70 664 exclusion phecode
364 Corneal opacity and other disorders of cornea Sense Organs 0.947 0.826 – 1.09 0.435 231 2495 exclusion phecode
364.1 Corneal opacity Sense Organs 0.967 0.771 – 1.21 0.771 85 931 exclusion phecode
364.2 Corneal edema Sense Organs 1 0.691 – 1.46 0.982 27 292 exclusion phecode
364.4 Corneal degenerations Sense Organs 0.946 0.765 – 1.17 0.609 94 990 exclusion phecode
364.41 Keratoconus Sense Organs 1.15 0.767 – 1.72 0.502 20 187 exclusion phecode
364.5 Corneal dystrophy Sense Organs 0.994 0.791 – 1.25 0.956 84 866 exclusion phecode
364.51 Fuchs' dystrophy Sense Organs 0.984 0.738 – 1.31 0.914 54 464 exclusion phecode
364.9 Cornea replaced by transplant Sense Organs 0.791 0.503 – 1.24 0.31 22 164 exclusion phecode
365 Glaucoma Sense Organs 1.01 0.921 – 1.12 0.777 467 4682 exclusion phecode
365.1 Open-angle glaucoma Sense Organs 0.977 0.794 – 1.2 0.827 108 1195 exclusion phecode
365.11 Primary open angle glaucoma Sense Organs 0.882 0.648 – 1.2 0.424 47 631 exclusion phecode
365.2 Primary angle-closure glaucoma Sense Organs 0.894 0.636 – 1.26 0.52 34 467 exclusion phecode
366 Cataract Sense Organs 0.922 0.867 – 0.98 0.00943 1475 6983 exclusion phecode
366.1 Nonsenile Cataract Sense Organs 1.08 0.758 – 1.55 0.656 36 375 exclusion phecode
366.2 Senile cataract Sense Organs 0.923 0.857 – 0.994 0.0351 915 5857 exclusion phecode
367
Disorders of refraction and accommodation
Disorders of refraction and accommodation; blindness and low vision
 Sense Organs 0.967 0.922 – 1.01 0.171 2289 10543 exclusion phecode
367.1 Myopia Sense Organs 0.966 0.911 – 1.02 0.246 1412 9925 exclusion phecode
367.2 Astigmatism Sense Organs 0.986 0.922 – 1.05 0.69 1045 9032 exclusion phecode
367.8 Hypermetropia Sense Organs 0.932 0.846 – 1.03 0.15 481 4557 exclusion phecode
367.9 Blindness and low vision Sense Organs 1.09 0.965 – 1.23 0.168 315 3028 exclusion phecode
368 Visual disturbances Sense Organs 0.997 0.943 – 1.05 0.923 1470 10996 exclusion phecode
368.1 Amblyopia Sense Organs 1.05 0.89 – 1.24 0.553 156 1765 exclusion phecode
368.2 Diplopia and disorders of binocular vision Sense Organs 0.876 0.767 – 0.999 0.0486 265 2545 exclusion phecode
368.3 Anisometropia Sense Organs 0.954 0.719 – 1.26 0.741 60 565 exclusion phecode
368.4 Visual field defects Sense Organs 0.923 0.802 – 1.06 0.269 220 2477 exclusion phecode
368.9 Subjective visual disturbances Sense Organs 1.03 0.912 – 1.17 0.601 280 2728 exclusion phecode
368.91 Psychophysical visual disturbances Sense Organs 1.55 1.01 – 2.37 0.0442 28 236 exclusion phecode
369 Infection of the eye Sense Organs 0.907 0.846 – 0.973 0.00612 937 8460 exclusion phecode
369.2 Eye infection, viral Sense Organs 0.828 0.689 – 0.996 0.0449 141 1373 exclusion phecode
369.5 Conjunctivitis, infectious Sense Organs 0.923 0.856 – 0.994 0.0338 813 7587 exclusion phecode
370 Keratitis Sense Organs 0.944 0.841 – 1.06 0.333 330 3350 exclusion phecode
370.1 Corneal ulcer Sense Organs 0.816 0.617 – 1.08 0.152 61 634 exclusion phecode
370.2 Superficial keratitis Sense Organs 0.922 0.771 – 1.1 0.372 137 1276 exclusion phecode
370.3 Keratoconjunctivitis Sense Organs 0.953 0.8 – 1.14 0.594 140 1508 exclusion phecode
370.31 Keratoconjunctivitis sicca Sense Organs 0.922 0.678 – 1.25 0.605 37 403 exclusion phecode
371 Inflammation of the eye Sense Organs 0.912 0.854 – 0.973 0.00575 1063 8629 exclusion phecode
371.1 Uveitis, noninfectious or NOS Sense Organs 0.921 0.763 – 1.11 0.395 121 1278 exclusion phecode
371.2 Conjunctivitis, noninfectious Sense Organs 0.878 0.766 – 1.01 0.0645 233 2543 exclusion phecode
371.21 Allergic conjunctivitis Sense Organs 0.906 0.781 – 1.05 0.192 197 2168 exclusion phecode
371.3 Inflammation of eyelids Sense Organs 0.902 0.836 – 0.974 0.0082 786 6730 exclusion phecode
371.33 Noninfectious dermatoses of eyelid Sense Organs 0.853 0.612 – 1.19 0.345 40 370 exclusion phecode
372 Disorders of conjunctiva Sense Organs 0.917 0.795 – 1.06 0.234 211 2391 exclusion phecode
374 Other disorders of eyelids Sense Organs 0.916 0.84 – 1 0.0492 589 5790 exclusion phecode
374.1 Ectropion or entropion Sense Organs 0.755 0.589 – 0.967 0.0263 70 797 exclusion phecode
374.2 Lagophthalmos Sense Organs 0.832 0.62 – 1.12 0.22 53 577 exclusion phecode
374.3 Ptosis of eyelid Sense Organs 0.98 0.844 – 1.14 0.79 195 2277 exclusion phecode
374.6 Dermatochalasis Sense Organs 0.914 0.781 – 1.07 0.26 171 1856 exclusion phecode
375 Disorders of lacrimal system Sense Organs 0.95 0.882 – 1.02 0.175 837 6858 exclusion phecode
375.1 Dry eyes Sense Organs 0.951 0.885 – 1.02 0.171 909 7100 exclusion phecode
375.2 Epiphora Sense Organs 0.817 0.66 – 1.01 0.0633 95 1044 exclusion phecode
376 Disorders of the orbit Sense Organs 0.905 0.729 – 1.12 0.368 90 944 exclusion phecode
377 Disorders of optic nerve and visual pathways Sense Organs 1.02 0.887 – 1.17 0.783 221 2417 exclusion phecode
377.1 Optic atrophy Sense Organs 0.947 0.744 – 1.21 0.657 73 677 exclusion phecode
377.3 Optic neuritis/neuropathy Sense Organs 1.1 0.922 – 1.31 0.298 139 1583 exclusion phecode
378
Strabismus and other disorders of binocular eye
Strabismus and other disorders of binocular eye movements
 Sense Organs 0.925 0.821 – 1.04 0.198 321 3260 exclusion phecode
378.1 Strabismus (not specified as paralytic) Sense Organs 0.898 0.777 – 1.04 0.146 212 2148 exclusion phecode
378.2 Nystagmus and other irregular eye movements Sense Organs 1.07 0.782 – 1.47 0.666 48 472 exclusion phecode
378.5 Paralytic strabismus Sense Organs 0.904 0.712 – 1.15 0.407 79 857 exclusion phecode
379 Other disorders of eye Sense Organs 0.936 0.874 – 1 0.0577 997 7637 exclusion phecode
379.1 Scleritis and episcleritis Sense Organs 1.23 0.926 – 1.64 0.151 49 502 exclusion phecode
379.2 Disorders of vitreous body Sense Organs 0.903 0.829 – 0.983 0.0185 649 5308 exclusion phecode
379.3 Aphakia and other disorders of lens Sense Organs 0.796 0.541 – 1.17 0.248 29 238 exclusion phecode
379.4 Anomalies of pupillary function Sense Organs 1.04 0.799 – 1.35 0.781 64 707 exclusion phecode
379.5 Disorders of iris and ciliary body Sense Organs 1.06 0.802 – 1.41 0.674 59 676 exclusion phecode
379.51 Pigmentary iris degeneration Sense Organs 1.2 0.72 – 2.01 0.481 18 190 exclusion phecode
379.9 Pain, swelling or discharge of eye Sense Organs 0.909 0.806 – 1.02 0.118 322 3215 exclusion phecode
380 Disorders of external ear Sense Organs 0.895 0.815 – 0.982 0.0191 528 4615 exclusion phecode
380.1 Otitis externa Sense Organs 1 0.901 – 1.12 0.965 389 4124 exclusion phecode
380.4 Impacted cerumen Sense Organs 0.866 0.796 – 0.943 0.000875 634 5538 exclusion phecode
381 Otitis media and Eustachian tube disorders Sense Organs 0.979 0.922 – 1.04 0.488 1259 10333 exclusion phecode
381.1 Otitis media Sense Organs 1 0.935 – 1.08 0.924 918 9055 exclusion phecode
381.11 Suppurative and unspecified otitis media Sense Organs 1 0.928 – 1.08 0.978 778 7895 exclusion phecode
381.2 Eustachian tube disorders Sense Organs 0.927 0.845 – 1.02 0.103 528 5207 exclusion phecode
381.3 Mastoiditis & related conditions Sense Organs 1 0.714 – 1.41 0.979 41 441 exclusion phecode
381.9 Otorrhea Sense Organs 1.06 0.858 – 1.31 0.583 103 1016 exclusion phecode
382 Otalgia Sense Organs 0.963 0.884 – 1.05 0.386 610 5920 exclusion phecode
383 Otosclerosis Sense Organs 0.647 0.452 – 0.925 0.0169 35 369 exclusion phecode
384 Other disorders of tympanic membrane Sense Organs 0.896 0.756 – 1.06 0.205 151 1483 exclusion phecode
384.1 Myringitis Sense Organs 0.564 0.312 – 1.02 0.058 15 144 exclusion phecode
384.4 Perforation of tympanic membrane Sense Organs 0.934 0.768 – 1.14 0.492 116 1146 exclusion phecode
385 Other disorders of middle ear and mastoid Sense Organs 0.91 0.743 – 1.11 0.363 109 1273 exclusion phecode
385.3 Cholesteatoma Sense Organs 0.874 0.687 – 1.11 0.271 75 848 exclusion phecode
385.5
Tympanosclerosis and middle ear disease related
Tympanosclerosis and middle ear disease related to otitis media
 Sense Organs 1.22 0.813 – 1.82 0.34 29 382 exclusion phecode
386
Vertiginous syndromes and other disorders of
Vertiginous syndromes and other disorders of vestibular system
 Sense Organs 1.01 0.91 – 1.11 0.907 441 4612 exclusion phecode
386.1 Meniere's disease Sense Organs 1.04 0.835 – 1.3 0.708 83 794 exclusion phecode
386.2 Peripheral or central vertigo Sense Organs 0.979 0.877 – 1.09 0.701 362 3816 exclusion phecode
386.21 Central origin vertigo Sense Organs 1.02 0.902 – 1.16 0.721 276 2906 exclusion phecode
386.3 Labyrinthitis Sense Organs 1.06 0.943 – 1.19 0.341 340 3692 exclusion phecode
386.9
Dizziness and giddiness (Light-headedness and
Dizziness and giddiness (Light-headedness and vertigo)
 Sense Organs 0.979 0.931 – 1.03 0.401 1934 10481 exclusion phecode
388 Other disorders of ear Sense Organs 0.851 0.75 – 0.966 0.0124 277 2635 exclusion phecode
389 Hearing loss Sense Organs 0.944 0.896 – 0.994 0.029 1771 10840 exclusion phecode
389.1 Sensorineural hearing loss Sense Organs 0.95 0.883 – 1.02 0.169 832 7198 exclusion phecode
389.2 Conductive hearing loss Sense Organs 0.856 0.75 – 0.978 0.0218 260 2754 exclusion phecode
389.3 Degenerative and vascular disorders of ear Sense Organs 0.865 0.609 – 1.23 0.418 33 365 exclusion phecode
389.4 Tinnitus Sense Organs 0.914 0.835 – 0.999 0.0483 555 5539 exclusion phecode
389.5 Disorders of acoustic nerve Sense Organs 0.906 0.642 – 1.28 0.572 34 333 exclusion phecode
394 Rheumatic disease of the heart valves Circulatory System 1.26 1.14 – 1.39 3.06e-06 548 2534 exclusion phecode
394.1 Mitral valve stenosis and aortic valve stenosis Circulatory System 1.2 0.976 – 1.46 0.0838 132 518 exclusion phecode
394.2 Mitral valve disease Circulatory System 1.23 1.03 – 1.47 0.0245 175 814 exclusion phecode
394.3 Aortic valve disease Circulatory System 0.992 0.743 – 1.33 0.959 64 244 exclusion phecode
394.4 Acute rheumatic heart disease Circulatory System 1.75 0.989 – 3.09 0.0545 21 122 exclusion phecode
394.7 Disease of tricuspid valve Circulatory System 1.46 1.27 – 1.69 2.55e-07 276 1080 exclusion phecode
395 Heart valve disorders Circulatory System 1.2 1.12 – 1.28 3.84e-08 1225 6432 exclusion phecode
395.1 Nonrheumatic mitral valve disorders Circulatory System 1.17 1.08 – 1.27 8.44e-05 776 4373 exclusion phecode
395.2 Nonrheumatic aortic valve disorders Circulatory System 1.2 1.09 – 1.32 0.000128 554 3063 exclusion phecode
395.3 Nonrheumatic tricuspid valve disorders Circulatory System 1.41 1.2 – 1.66 2.28e-05 237 918 exclusion phecode
395.4 Nonrheumatic pulmonary valve disorders Circulatory System 1.16 0.856 – 1.56 0.343 45 289 exclusion phecode
395.6 Heart valve replaced Circulatory System 1.12 1 – 1.25 0.0489 406 1826 exclusion phecode
396 Abnormal heart sounds Circulatory System 1.11 1.04 – 1.18 0.00129 1245 9086 exclusion phecode
401 Hypertension Circulatory System 1.47 1.4 – 1.54 1.74e-55 3333 9450 exclusion phecode
401.1 Essential hypertension Circulatory System 1.48 1.41 – 1.55 1.38e-56 3266 9447 exclusion phecode
401.2 Hypertensive heart and/or renal disease Circulatory System 1.79 1.63 – 1.96 8.31e-36 728 4936 exclusion phecode
401.21 Hypertensive heart disease Circulatory System 1.82 1.57 – 2.1 1.44e-15 261 1891 exclusion phecode
401.22 Hypertensive chronic kidney disease Circulatory System 1.85 1.65 – 2.06 1.59e-27 441 4290 exclusion phecode
401.3 Other hypertensive complications Circulatory System 1.46 1.29 – 1.66 4.88e-09 281 5602 exclusion phecode
411 Ischemic Heart Disease Circulatory System 1.22 1.15 – 1.29 4.18e-12 1982 7317 exclusion phecode
411.1 Unstable angina (intermediate coronary syndrome) Circulatory System 1.35 1.16 – 1.58 0.000135 196 1391 exclusion phecode
411.2 Myocardial infarction Circulatory System 1.36 1.25 – 1.47 1.62e-14 884 4243 exclusion phecode
411.3 Angina pectoris Circulatory System 1.3 1.18 – 1.43 4.6e-08 561 3460 exclusion phecode
411.4 Coronary atherosclerosis Circulatory System 1.27 1.2 – 1.35 1.81e-14 1637 6123 exclusion phecode
411.41 Aneurysm and dissection of heart Circulatory System 1.37 0.998 – 1.88 0.0515 54 281 exclusion phecode
411.8
Other chronic ischemic heart disease
Other chronic ischemic heart disease, unspecified
 Circulatory System 1.32 1.24 – 1.41 1.05e-16 1412 5415 exclusion phecode
411.9
Other acute and subacute forms of ischemic
Other acute and subacute forms of ischemic heart disease
 Circulatory System 1.46 1.2 – 1.78 0.000201 133 692 exclusion phecode
414 Other forms of chronic heart disease Circulatory System 1.24 1.15 – 1.33 1.15e-08 1003 4669 exclusion phecode
414.2 ASCVD Circulatory System 1.24 1.06 – 1.45 0.0073 195 1164 exclusion phecode
415 Pulmonary heart disease Circulatory System 1.22 1.14 – 1.3 6.38e-09 1049 6666 exclusion phecode
415.1 Acute pulmonary heart disease Circulatory System 1.07 0.978 – 1.17 0.14 554 4156 exclusion phecode
415.11 Pulmonary embolism and infarction, acute Circulatory System 1.07 0.974 – 1.17 0.162 551 4134 exclusion phecode
415.2 Chronic pulmonary heart disease Circulatory System 1.4 1.28 – 1.53 1.6e-13 615 3493 exclusion phecode
415.21 Primary pulmonary hypertension Circulatory System 1.46 1.28 – 1.68 3.81e-08 253 1385 exclusion phecode
416 Cardiomegaly Circulatory System 1.29 1.14 – 1.45 2.75e-05 339 2503 exclusion phecode
418 Nonspecific chest pain Circulatory System 1.05 1 – 1.09 0.0296 3531 9246 exclusion phecode
418.1 Precordial pain Circulatory System 1.13 1.01 – 1.27 0.0328 338 2870 exclusion phecode
420 Carditis Circulatory System 1.17 1.06 – 1.28 0.00107 569 3051 exclusion phecode
420.1 Myocarditis Circulatory System 0.845 0.608 – 1.17 0.316 50 221 exclusion phecode
420.2 Pericarditis Circulatory System 1.21 1.07 – 1.37 0.003 312 1686 exclusion phecode
420.21 Acute pericarditis Circulatory System 1.19 0.925 – 1.54 0.174 69 398 exclusion phecode
420.22 Chronic pericarditis Circulatory System 1.53 1.12 – 2.1 0.00834 55 229 exclusion phecode
420.3 Endocarditis Circulatory System 1.13 0.982 – 1.3 0.0882 255 1351 exclusion phecode
425 Cardiomyopathy Circulatory System 1.32 1.22 – 1.43 5.79e-12 825 3671 exclusion phecode
425.1 Primary/intrinsic cardiomyopathies Circulatory System 1.31 1.21 – 1.42 3.15e-11 793 3464 exclusion phecode
425.11 Hypertrophic obstructive cardiomyopathy Circulatory System 1.38 1.09 – 1.75 0.00815 92 376 exclusion phecode
425.12 Other hypertrophic cardiomyopathy Circulatory System 1.23 0.941 – 1.6 0.13 70 419 exclusion phecode
425.2 Secondary/extrinsic cardiomyopathies Circulatory System 1.32 1.12 – 1.56 0.00121 167 648 exclusion phecode
425.8 Other cardiomyopathy Circulatory System 1.62 1.1 – 2.39 0.0145 37 189 exclusion phecode
426 Cardiac conduction disorders Circulatory System 1.11 1.06 – 1.17 2.31e-05 3131 7038 exclusion phecode
426.2 Atrioventricular [AV] block Circulatory System 1.22 1.1 – 1.35 0.000273 539 1970 exclusion phecode
426.21 First degree AV block Circulatory System 1.16 1.02 – 1.32 0.0219 343 1377 exclusion phecode
426.22 Mobitz II AV block Circulatory System 1.1 0.57 – 2.13 0.771 12 76 exclusion phecode
426.23 Second degree AV block Circulatory System 1.18 0.84 – 1.66 0.341 46 252 exclusion phecode
426.24 Atrioventricular block, complete Circulatory System 1.39 1.15 – 1.68 0.000596 173 558 exclusion phecode
426.25 Other heart block Circulatory System 1.07 0.792 – 1.44 0.662 54 261 exclusion phecode
426.3 Bundle branch block Circulatory System 1.31 1.19 – 1.44 2.72e-08 623 2523 exclusion phecode
426.31 Right bundle branch block Circulatory System 1.25 1.11 – 1.4 0.000239 368 1780 exclusion phecode
426.32 Left bundle branch block Circulatory System 1.38 1.19 – 1.59 1.04e-05 289 1232 exclusion phecode
426.4 Anomalous atrioventricular excitation Circulatory System 1.15 0.79 – 1.68 0.461 31 234 exclusion phecode
426.7 Abnormal electrocardiogram [ECG] [EKG] Circulatory System 1.12 1.07 – 1.18 7.31e-06 2706 6959 exclusion phecode
426.8 Other cardiac conduction disorders Circulatory System 1.34 1.14 – 1.57 0.000311 188 1371 exclusion phecode
426.9 Cardiac pacemaker/device in situ Circulatory System 1.39 1.26 – 1.53 5.51e-11 648 1978 exclusion phecode
426.91 Cardiac pacemaker in situ Circulatory System 1.39 1.23 – 1.58 2.09e-07 398 1259 exclusion phecode
426.92 Cardiac defibrillator in situ Circulatory System 1.48 1.31 – 1.68 7.32e-10 417 1107 exclusion phecode
427 Cardiac dysrhythmias Circulatory System 1.08 1.04 – 1.12 0.000136 4923 7159 exclusion phecode
427.1 Paroxysmal tachycardia, unspecified Circulatory System 1.19 1.1 – 1.28 8.87e-06 929 4167 exclusion phecode
427.11 Paroxysmal supraventricular tachycardia Circulatory System 1.14 1.04 – 1.25 0.00678 583 3234 exclusion phecode
427.12 Paroxysmal ventricular tachycardia Circulatory System 1.26 1.13 – 1.4 1.99e-05 487 1705 exclusion phecode
427.2 Atrial fibrillation and flutter Circulatory System 1.19 1.11 – 1.27 7.5e-07 1570 3928 exclusion phecode
427.21 Atrial fibrillation Circulatory System 1.18 1.1 – 1.27 1.66e-06 1530 3832 exclusion phecode
427.22 Atrial flutter Circulatory System 1.21 1.1 – 1.34 0.000135 604 1715 exclusion phecode
427.3 Other specified cardiac dysrhythmias Circulatory System 1.11 1.05 – 1.16 8.97e-05 2463 7091 exclusion phecode
427.4 Cardiac arrest and ventricular fibrillation Circulatory System 1.54 1.3 – 1.81 2.49e-07 216 957 exclusion phecode
427.41 Ventricular fibrillation and flutter Circulatory System 1.51 1.18 – 1.94 0.00127 104 351 exclusion phecode
427.42 Cardiac arrest Circulatory System 1.68 1.39 – 2.03 1.08e-07 154 703 exclusion phecode
427.5 Arrhythmia (cardiac) NOS Circulatory System 1.1 1.04 – 1.16 0.000405 2065 7056 exclusion phecode
427.6 Premature beats Circulatory System 1.22 1.12 – 1.33 8.32e-06 671 3420 exclusion phecode
427.61 Supraventricular premature beats Circulatory System 1.15 0.976 – 1.36 0.0943 167 1065 exclusion phecode
427.7 Tachycardia NOS Circulatory System 1.11 1.05 – 1.18 0.000142 1730 7083 exclusion phecode
427.8 Sinoatrial node dysfunction (Bradycardia) Circulatory System 1.19 1.03 – 1.39 0.0213 232 1218 exclusion phecode
427.9 Palpitations Circulatory System 1.06 0.996 – 1.13 0.0658 1359 6852 exclusion phecode
428 Congestive heart failure; nonhypertensive Circulatory System 1.27 1.19 – 1.36 5.7e-13 1351 5030 exclusion phecode
428.1 Congestive heart failure (CHF) NOS Circulatory System 1.28 1.19 – 1.37 1.87e-12 1228 4623 exclusion phecode
428.2 Heart failure NOS Circulatory System 1.34 1.25 – 1.43 7.36e-16 1174 4365 exclusion phecode
428.3
Heart failure with reduced EF [Systolic or
Heart failure with reduced EF [Systolic or combined heart failure]
 Circulatory System 1.41 1.29 – 1.54 1.31e-14 748 2505 exclusion phecode
428.4
Heart failure with preserved EF [Diastolic
Heart failure with preserved EF [Diastolic heart failure]
 Circulatory System 1.4 1.26 – 1.55 2.02e-10 473 2335 exclusion phecode
429
Ill-defined descriptions and complications of
Ill-defined descriptions and complications of heart disease
 Circulatory System 1.11 1.07 – 1.16 5.95e-07 3412 8936 exclusion phecode
429.1 Heart transplant/surgery Circulatory System 1.21 1.1 – 1.34 0.000183 488 2112 exclusion phecode
429.2 Abnormal function study of cardiovascular system Circulatory System 1.19 1.12 – 1.27 7.48e-09 1562 7509 exclusion phecode
429.3 Symptoms involving cardiovascular system Circulatory System 1.1 1.06 – 1.15 1.74e-05 2782 8916 exclusion phecode
429.9 Cardiac complications, not elsewhere classified Circulatory System 1.31 1.14 – 1.5 0.000162 246 1180 exclusion phecode
430 Intracranial hemorrhage Circulatory System 1.24 1.06 – 1.45 0.00879 175 1675 exclusion phecode
430.1 Subarachnoid hemorrhage Circulatory System 1.46 1.08 – 1.97 0.0129 56 583 exclusion phecode
430.2 Intracerebral hemorrhage Circulatory System 1.05 0.824 – 1.33 0.705 75 793 exclusion phecode
430.3 Subdural hemorrhage Circulatory System 1.4 1.04 – 1.89 0.0259 50 510 exclusion phecode
433 Cerebrovascular disease Circulatory System 1.22 1.14 – 1.3 2.86e-09 1153 7832 exclusion phecode
433.1 Occlusion and stenosis of precerebral arteries Circulatory System 1.24 1.11 – 1.38 0.00021 352 3033 exclusion phecode
433.11
Occlusion of cerebral arteries, with cerebral
Occlusion of cerebral arteries, with cerebral infarction
 Circulatory System 1.36 1.01 – 1.83 0.0453 45 492 exclusion phecode
433.12 Cerebral atherosclerosis Circulatory System 1.12 0.647 – 1.93 0.69 14 139 exclusion phecode
433.2 Occlusion of cerebral arteries Circulatory System 1.29 1.18 – 1.42 8.2e-08 511 4658 exclusion phecode
433.21
Cerebral artery occlusion, with cerebral
Cerebral artery occlusion, with cerebral infarction
 Circulatory System 1.3 1.18 – 1.43 8.47e-08 485 4492 exclusion phecode
433.3 Cerebral ischemia Circulatory System 1.18 1.08 – 1.3 0.000242 553 4840 exclusion phecode
433.31 Transient cerebral ischemia Circulatory System 1.2 1.09 – 1.32 0.000196 486 4350 exclusion phecode
433.5 Cerebral aneurysm Circulatory System 1.27 1.04 – 1.55 0.0208 109 1146 exclusion phecode
433.6 Acute, but ill-defined cerebrovascular disease Circulatory System 1.22 0.995 – 1.51 0.0557 99 872 exclusion phecode
433.8 Late effects of cerebrovascular disease Circulatory System 1.35 1.13 – 1.61 0.000741 140 1436 exclusion phecode
440 Atherosclerosis Circulatory System 1.28 1.17 – 1.41 1.7e-07 511 3883 exclusion phecode
440.1 Atherosclerosis of renal artery Circulatory System 1.6 1.09 – 2.35 0.0154 21 412 exclusion phecode
440.2 Atherosclerosis of the extremities Circulatory System 1.32 1.17 – 1.49 6.59e-06 306 2576 exclusion phecode
440.21
Atherosclerosis of native arteries of the
Atherosclerosis of native arteries of the extremities with ulceration or gangrene
 Circulatory System 1.46 1.11 – 1.92 0.00758 51 456 exclusion phecode
440.22
Atherosclerosis of native arteries of the
Atherosclerosis of native arteries of the extremities with intermittent claudication
 Circulatory System 1.3 1.12 – 1.51 0.000504 208 1774 exclusion phecode
440.9 Atherosclerosis of aorta Circulatory System 1.27 1.08 – 1.48 0.00312 188 1364 exclusion phecode
441 Vascular insufficiency of intestine Circulatory System 1.24 1.05 – 1.47 0.0106 159 1055 exclusion phecode
441.1 Acute vascular insufficiency of intestine Circulatory System 1.41 1.09 – 1.83 0.00867 73 518 exclusion phecode
441.2 Chronic vascular insufficiency of intestine Circulatory System 1.43 1.05 – 1.95 0.0218 45 285 exclusion phecode
442 Other aneurysm Circulatory System 1.08 0.995 – 1.17 0.0668 701 4398 exclusion phecode
442.1 Aortic aneurysm Circulatory System 1.04 0.947 – 1.14 0.415 530 3056 exclusion phecode
442.11 Abdominal aortic aneurysm Circulatory System 1.07 0.938 – 1.21 0.329 283 1743 exclusion phecode
442.2 Aneurysm of iliac artery Circulatory System 1.1 0.77 – 1.58 0.593 38 319 exclusion phecode
442.3 Aneurysm of artery of lower extremity Circulatory System 1.02 0.747 – 1.39 0.904 46 328 exclusion phecode
442.4 Arterial dissection Circulatory System 1.18 0.866 – 1.6 0.296 41 391 exclusion phecode
442.8 Aneurysm of other specified artery Circulatory System 1.14 0.932 – 1.41 0.198 102 829 exclusion phecode
443 Peripheral vascular disease Circulatory System 1.18 1.09 – 1.28 3.28e-05 714 5668 exclusion phecode
443.1 Raynaud's syndrome Circulatory System 0.984 0.865 – 1.12 0.812 268 2117 exclusion phecode
443.7
Peripheral angiopathy in diseases classified
Peripheral angiopathy in diseases classified elsewhere
 Circulatory System 1.38 0.998 – 1.9 0.0514 37 358 exclusion phecode
443.8 Other specified peripheral vascular diseases Circulatory System 1.22 1.12 – 1.33 8.66e-06 582 4865 exclusion phecode
443.9 Peripheral vascular disease, unspecified Circulatory System 1.31 1.19 – 1.45 1.24e-07 454 3648 exclusion phecode
444 Arterial embolism and thrombosis Circulatory System 1.21 1.06 – 1.39 0.00615 233 1764 exclusion phecode
444.1
Arterial embolism and thrombosis of lower
Arterial embolism and thrombosis of lower extremity artery
 Circulatory System 1.25 0.993 – 1.57 0.0571 78 572 exclusion phecode
444.2 Embolism and thrombosis of abdominal aorta Circulatory System 1.15 0.781 – 1.71 0.472 31 267 exclusion phecode
446 Polyarteritis nodosa and allied conditions Circulatory System 1.12 0.911 – 1.38 0.282 99 1051 exclusion phecode
446.4 Wegener's granulomatosis Circulatory System 1.04 0.698 – 1.54 0.86 24 272 exclusion phecode
446.5 Giant cell arteritis Circulatory System 0.82 0.446 – 1.51 0.524 11 131 exclusion phecode
446.9 Arteritis NOS Circulatory System 1.17 0.916 – 1.51 0.205 67 685 exclusion phecode
447 Other disorders of arteries and arterioles Circulatory System 1.12 1.03 – 1.22 0.0114 608 4880 exclusion phecode
447.1 Stricture of artery Circulatory System 1.14 0.946 – 1.37 0.171 122 1034 exclusion phecode
447.7 Aortic ectasia Circulatory System 1 0.859 – 1.17 0.978 197 1469 exclusion phecode
448 Disease of capillaries Circulatory System 0.922 0.817 – 1.04 0.192 310 2768 exclusion phecode
450 Noninfectious disorders of lymphatic channels Circulatory System 1.01 0.923 – 1.1 0.839 550 5316 exclusion phecode
451 Phlebitis and thrombophlebitis Circulatory System 1.07 0.925 – 1.24 0.368 204 1832 exclusion phecode
451.2
Phlebitis and thrombophlebitis of lower
Phlebitis and thrombophlebitis of lower extremities
 Circulatory System 1.04 0.801 – 1.35 0.771 65 603 exclusion phecode
452 Other venous embolism and thrombosis Circulatory System 1.12 1.06 – 1.19 0.000185 1407 7866 exclusion phecode
452.1 Iatrogenic pulmonary embolism and infarction Circulatory System 0.926 0.736 – 1.16 0.511 86 640 exclusion phecode
452.2 Deep vein thrombosis [DVT] Circulatory System 1.14 1.06 – 1.22 0.000366 915 6607 exclusion phecode
452.8 Postphlebitic syndrome Circulatory System 0.914 0.686 – 1.22 0.536 52 435 exclusion phecode
453 Chronic venous hypertension Circulatory System 0.919 0.702 – 1.2 0.535 62 547 exclusion phecode
454 Varicose veins Circulatory System 1.02 0.948 – 1.1 0.549 789 6137 exclusion phecode
454.1 Varicose veins of lower extremity Circulatory System 1.02 0.934 – 1.1 0.713 659 5393 exclusion phecode
454.11 Varicose veins of lower extremity, symptomtic Circulatory System 1 0.906 – 1.11 0.925 427 3647 exclusion phecode
455 Hemorrhoids Circulatory System 0.969 0.915 – 1.03 0.278 1511 8038 exclusion phecode
456 Chronic venous insufficiency [CVI] Circulatory System 1.01 0.939 – 1.09 0.747 811 6416 exclusion phecode
457
Encounter for long-term (current) use of
Encounter for long-term (current) use of anticoagulants, antithrombotics, aspirin
 Circulatory System 1.26 1.14 – 1.39 6.89e-06 495 3022 exclusion phecode
457.2
Encounter for long-term (current) use of
Encounter for long-term (current) use of antiplatelets/antithrombotics
 Circulatory System 1.61 1.27 – 2.05 8.71e-05 88 566 exclusion phecode
457.3 Encounter for long-term (current) use of aspirin Circulatory System 1.23 1.11 – 1.36 7.21e-05 462 2881 exclusion phecode
458 Hypotension Circulatory System 1.12 1.06 – 1.18 1.82e-05 2073 7935 exclusion phecode
458.1 Orthostatic hypotension Circulatory System 1.03 0.931 – 1.14 0.557 457 2715 exclusion phecode
458.2 Iatrogenic hypotension Circulatory System 1.22 1.1 – 1.36 0.00022 485 1984 exclusion phecode
458.9 Hypotension NOS Circulatory System 1.13 1.07 – 1.19 9.56e-06 1898 7492 exclusion phecode
459 Other disorders of circulatory system Circulatory System 1.15 1.09 – 1.21 1.24e-07 2118 8977 exclusion phecode
459.1 Hemorrhage NOS Circulatory System 1.09 0.945 – 1.25 0.244 251 1786 exclusion phecode
459.7 Blood vessel replaced Circulatory System 1.1 0.985 – 1.23 0.0916 383 2616 exclusion phecode
459.9 Circulatory disease NEC Circulatory System 1.16 1.09 – 1.22 2.82e-07 1770 8474 exclusion phecode
464 Acute sinusitis Respiratory 0.972 0.917 – 1.03 0.339 1406 8787 exclusion phecode
465
Acute upper respiratory infections of multiple
Acute upper respiratory infections of multiple or unspecified sites
 Respiratory 0.943 0.904 – 0.985 0.00788 2998 9483 exclusion phecode
465.2 Acute pharyngitis Respiratory 0.951 0.903 – 1 0.0603 1877 8896 exclusion phecode
465.4 Acute laryngitis and tracheitis Respiratory 1.18 0.976 – 1.42 0.0886 121 1252 exclusion phecode
470 Septal Deviations/Turbinate Hypertrophy Respiratory 0.888 0.805 – 0.978 0.0162 484 5009 exclusion phecode
471 Nasal polyps Respiratory 1.08 0.903 – 1.29 0.404 136 1536 exclusion phecode
472 Chronic pharyngitis and nasopharyngitis Respiratory 0.974 0.883 – 1.07 0.59 468 4723 exclusion phecode
473 Diseases of the larynx and vocal cords Respiratory 0.996 0.922 – 1.08 0.926 748 6607 exclusion phecode
473.1 Chronic laryngitis Respiratory 1.2 0.766 – 1.88 0.426 18 199 exclusion phecode
473.3 Paralysis/spasm of vocal cords or larynx Respiratory 1.09 0.924 – 1.28 0.311 170 1603 exclusion phecode
473.4 Voice disturbance Respiratory 1.01 0.922 – 1.1 0.883 578 5528 exclusion phecode
474 Acute and chronic tonsillitis Respiratory 0.936 0.831 – 1.05 0.278 339 2909 exclusion phecode
474.1 Acute tonsillitis Respiratory 0.853 0.712 – 1.02 0.0853 150 1371 exclusion phecode
474.2 Chronic tonsillitis and adenoiditis Respiratory 0.947 0.828 – 1.08 0.42 264 2422 exclusion phecode
475 Chronic sinusitis Respiratory 0.927 0.87 – 0.988 0.0204 1190 7568 exclusion phecode
475.9 Postnasal drip Respiratory 0.927 0.813 – 1.06 0.254 256 2315 exclusion phecode
476 Allergic rhinitis Respiratory 0.972 0.933 – 1.01 0.186 3557 7637 exclusion phecode
477 Epistaxis or throat hemorrhage Respiratory 1.16 1.03 – 1.3 0.0145 325 2916 exclusion phecode
478 Throat pain Respiratory 1.02 0.837 – 1.24 0.857 121 1278 exclusion phecode
479 Other upper respiratory disease Respiratory 1.02 0.966 – 1.08 0.44 1535 7615 exclusion phecode
480 Pneumonia Respiratory 1.09 1.04 – 1.15 0.000946 1708 9924 exclusion phecode
480.1 Bacterial pneumonia Respiratory 1.16 1.04 – 1.3 0.00752 377 2581 exclusion phecode
480.11 Pneumococcal pneumonia Respiratory 1.08 0.912 – 1.27 0.382 177 1286 exclusion phecode
480.12 Pseudomonal pneumonia Respiratory 1.18 0.869 – 1.6 0.289 48 348 exclusion phecode
480.13 MRSA pneumonia Respiratory 1.17 0.856 – 1.59 0.331 41 275 exclusion phecode
480.2 Viral pneumonia Respiratory 1.21 0.933 – 1.57 0.15 63 412 exclusion phecode
480.3 Pneumonia due to fungus (mycoses) Respiratory 1.28 0.954 – 1.72 0.0992 55 359 exclusion phecode
480.5 Bronchopneumonia and lung abscess Respiratory 0.874 0.623 – 1.23 0.438 47 277 exclusion phecode
481 Influenza Respiratory 0.948 0.853 – 1.05 0.321 409 3766 exclusion phecode
483 Acute bronchitis and bronchiolitis Respiratory 1.01 0.939 – 1.08 0.839 919 8093 exclusion phecode
495 Asthma Respiratory 1.04 0.996 – 1.09 0.0736 2513 9177 exclusion phecode
495.1 Chronic obstructive asthma Respiratory 1.35 1.11 – 1.65 0.00286 112 928 exclusion phecode
495.11 Chronic obstructive asthma with exacerbation Respiratory 1.02 0.662 – 1.58 0.919 19 163 exclusion phecode
495.2 Asthma with exacerbation Respiratory 1.02 0.926 – 1.12 0.722 495 5259 exclusion phecode
496 Chronic airway obstruction Respiratory 1.11 1.04 – 1.18 0.000801 1343 6955 exclusion phecode
496.1 Emphysema Respiratory 1.11 1.02 – 1.22 0.0196 547 3897 exclusion phecode
496.2 Chronic bronchitis Respiratory 1.13 1.05 – 1.21 0.000576 1019 6282 exclusion phecode
496.21 Obstructive chronic bronchitis Respiratory 1.14 1.06 – 1.23 0.000389 906 5754 exclusion phecode
496.3 Bronchiectasis Respiratory 1.09 0.918 – 1.3 0.319 150 1140 exclusion phecode
497 Bronchitis Respiratory 0.975 0.887 – 1.07 0.591 498 5079 exclusion phecode
498 Acute bronchospasm Respiratory 1.07 0.896 – 1.29 0.443 128 1386 exclusion phecode
499 Cystic fibrosis Respiratory 1.09 0.819 – 1.45 0.553 54 503 exclusion phecode
500 Lung disease due to external agents Respiratory 1.18 1.01 – 1.4 0.0431 170 1049 exclusion phecode
500.1 Extrinsic allergic alveolitis Respiratory 1.06 0.738 – 1.53 0.743 29 182 exclusion phecode
500.2 Pneumoconiosis Respiratory 0.994 0.549 – 1.8 0.985 20 101 exclusion phecode
501 Pneumonitis due to inhalation of food or vomitus Respiratory 1.27 1.08 – 1.49 0.00408 185 1087 exclusion phecode
502 Postinflammatory pulmonary fibrosis Respiratory 1.18 1.02 – 1.36 0.0253 235 1490 exclusion phecode
503 Pulmonary congestion and hypostasis Respiratory 1.23 1.08 – 1.41 0.00167 284 1534 exclusion phecode
504 Other alveolar and parietoalveolar pneumonopathy Respiratory 1.29 1.1 – 1.51 0.00204 183 1106 exclusion phecode
504.1 Idiopathic fibrosing alveolitis Respiratory 1.07 0.862 – 1.33 0.541 103 541 exclusion phecode
505 Other pulmonary inflamation or edema Respiratory 1.29 1.17 – 1.42 4.24e-07 517 2986 exclusion phecode
506 Empyema and pneumothorax Respiratory 1.18 1.1 – 1.26 2.43e-06 1043 5313 exclusion phecode
507 Pleurisy; pleural effusion Respiratory 1.14 1.07 – 1.23 0.000121 1009 5672 exclusion phecode
508
Pulmonary collapse; interstitial and
Pulmonary collapse; interstitial and compensatory emphysema
 Respiratory 1.15 1.06 – 1.25 0.000516 728 4673 exclusion phecode
509 Respiratory failure, insufficiency, arrest Respiratory 1.18 1.1 – 1.25 4.1e-07 1275 6454 exclusion phecode
509.1 Respiratory failure Respiratory 1.26 1.16 – 1.37 1.74e-07 647 3769 exclusion phecode
509.2 Respiratory insufficiency Respiratory 1.23 1.1 – 1.37 0.000193 394 2230 exclusion phecode
509.3
Pulmonary insufficiency or respiratory failure
Pulmonary insufficiency or respiratory failure following trauma and surgery
 Respiratory 1.23 1.12 – 1.35 1.15e-05 582 3168 exclusion phecode
509.8
Dependence on respirator [Ventilator] or
Dependence on respirator [Ventilator] or supplemental oxygen
 Respiratory 1.23 1.12 – 1.36 1.04e-05 529 3301 exclusion phecode
510 Other diseases of lung Respiratory 1.1 1.04 – 1.16 0.00164 1481 8972 exclusion phecode
510.2 Lung transplant Respiratory 1.05 0.79 – 1.41 0.718 51 412 exclusion phecode
512 Other symptoms of respiratory system Respiratory 1.05 1.01 – 1.09 0.0118 5283 7555 exclusion phecode
512.1 Wheezing Respiratory 1.04 0.926 – 1.16 0.521 338 3309 exclusion phecode
512.2 Painful respiration Respiratory 1.04 0.965 – 1.13 0.283 716 5639 exclusion phecode
512.3 Abnormal chest sounds Respiratory 1.26 0.987 – 1.6 0.0635 72 526 exclusion phecode
512.7 Shortness of breath Respiratory 1.09 1.04 – 1.14 0.000241 2872 7531 exclusion phecode
512.8 Cough Respiratory 1.02 0.977 – 1.07 0.335 2679 7553 exclusion phecode
512.9 Other dyspnea Respiratory 1.08 1.03 – 1.13 0.000977 3042 7537 exclusion phecode
513 Respiratory abnormalities Respiratory 1.06 1.02 – 1.1 0.0059 3635 9194 exclusion phecode
513.3 Hypoventilation Respiratory 0.987 0.855 – 1.14 0.854 220 1892 exclusion phecode
513.31 Apnea Respiratory 0.945 0.771 – 1.16 0.587 108 1025 exclusion phecode
513.32 Orthopnea Respiratory 0.935 0.707 – 1.24 0.638 58 381 exclusion phecode
513.4 Hyperventilation Respiratory 1.08 0.915 – 1.27 0.366 177 1038 exclusion phecode
513.8 Disorders of diaphragm Respiratory 0.851 0.639 – 1.13 0.268 64 464 exclusion phecode
514 Abnormal findings examination of lungs Respiratory 1.08 1.02 – 1.14 0.0137 1376 8545 exclusion phecode
514.1
Abnormal results of function study of pulmonary
Abnormal results of function study of pulmonary system
 Respiratory 1.04 0.814 – 1.32 0.766 80 590 exclusion phecode
514.2 Solitary pulmonary nodule Respiratory 1.08 0.996 – 1.16 0.0616 747 6035 exclusion phecode
516 Abnormal sputum Respiratory 1.14 0.985 – 1.31 0.0799 215 1666 exclusion phecode
516.1 Hemoptysis Respiratory 1.03 0.879 – 1.2 0.725 179 1414 exclusion phecode
519
Other diseases of respiratory system, not
Other diseases of respiratory system, not elsewhere classified
 Respiratory 1.11 1.06 – 1.17 3.35e-05 1939 10380 exclusion phecode
519.1 Tracheostomy complications Respiratory 1.19 0.879 – 1.6 0.266 49 477 exclusion phecode
519.2 Respiratory complications Respiratory 1.26 1.07 – 1.48 0.00573 177 962 exclusion phecode
519.8 Other diseases of respiratory system, NEC Respiratory 1.01 0.913 – 1.12 0.842 431 3924 exclusion phecode
519.9
Symptoms involving respiratory system and other
Symptoms involving respiratory system and other chest symptoms
 Respiratory 1.13 1.06 – 1.19 5.56e-05 1432 8463 exclusion phecode
520 Disorders of tooth development Digestive 0.886 0.731 – 1.08 0.221 117 1100 exclusion phecode
520.1 Hereditary disturbances in tooth structure Digestive 0.915 0.676 – 1.24 0.565 45 421 exclusion phecode
520.2 Disturbances in tooth eruption Digestive 0.889 0.702 – 1.13 0.327 77 723 exclusion phecode
521 Diseases of hard tissues of teeth Digestive 1.2 1.05 – 1.36 0.00603 276 2354 exclusion phecode
521.1 Dental caries Digestive 1.17 1.03 – 1.34 0.0194 262 2192 exclusion phecode
521.2 Dental abrasion, erosion and attrition Digestive 1.61 0.871 – 2.97 0.129 14 134 exclusion phecode
522 Diseases of pulp and periapical tissues Digestive 0.983 0.835 – 1.16 0.834 164 1509 exclusion phecode
522.5 Periapical abscess Digestive 0.93 0.778 – 1.11 0.426 137 1304 exclusion phecode
523 Gingival and periodontal diseases Digestive 0.998 0.861 – 1.16 0.98 201 1915 exclusion phecode
523.1 Gingivitis Digestive 1.08 0.801 – 1.46 0.614 47 414 exclusion phecode
523.3 Periodontitis (acute or chronic) Digestive 0.903 0.73 – 1.12 0.343 102 982 exclusion phecode
523.31 Acute periodontitis Digestive 0.87 0.683 – 1.11 0.257 79 845 exclusion phecode
523.32 Chronic periodontitis Digestive 1.03 0.733 – 1.45 0.861 36 277 exclusion phecode
524 Dentofacial anomalies, including malocclusion Digestive 0.837 0.689 – 1.02 0.0724 119 1276 exclusion phecode
524.3 Anomalies of tooth position/malocclusion Digestive 0.836 0.655 – 1.07 0.151 77 782 exclusion phecode
525
Other diseases of the teeth and supporting
Other diseases of the teeth and supporting structures
 Digestive 1.09 0.966 – 1.23 0.162 309 2989 exclusion phecode
525.1 Loss of teeth or edentulism Digestive 1.03 0.828 – 1.27 0.811 97 1038 exclusion phecode
526 Diseases of the jaws Digestive 0.917 0.852 – 0.986 0.0201 846 8062 exclusion phecode
526.1 Cysts of the jaws Digestive 0.888 0.641 – 1.23 0.474 41 660 exclusion phecode
526.3 Anomalies of jaw size/symmetry Digestive 0.707 0.565 – 0.883 0.00227 98 883 exclusion phecode
526.4 Temporomandibular joint disorders Digestive 0.918 0.837 – 1.01 0.0687 532 4941 exclusion phecode
526.41 Temporomandibular joint disorder, unspecified Digestive 0.952 0.859 – 1.05 0.343 436 3981 exclusion phecode
526.42 Arthralgia/ankylosis of temporomandibular joint Digestive 0.893 0.784 – 1.02 0.0878 269 2609 exclusion phecode
526.5 Inflammatory conditions of jaw Digestive 0.944 0.742 – 1.2 0.637 77 779 exclusion phecode
526.8 Exostosis of jaw Digestive 0.664 0.374 – 1.18 0.163 14 123 exclusion phecode
526.9 Jaw disease NOS Digestive 1.01 0.833 – 1.21 0.957 125 1323 exclusion phecode
527 Diseases of the salivary glands Digestive 0.993 0.893 – 1.1 0.891 401 4358 exclusion phecode
527.1 Hypertrophy of salivary gland Digestive 2.32 1.18 – 4.55 0.0143 10 149 exclusion phecode
527.2 Sialoadenitis Digestive 0.786 0.623 – 0.992 0.0423 83 1053 exclusion phecode
527.7 Disturbance of salivary secretion Digestive 0.956 0.83 – 1.1 0.536 226 2084 exclusion phecode
527.8 Other specified diseases of the salivary glands Digestive 0.994 0.733 – 1.35 0.972 43 581 exclusion phecode
528
Diseases of the oral soft tissues, excluding
Diseases of the oral soft tissues, excluding lesions specific for gingiva and tongue
 Digestive 0.932 0.862 – 1.01 0.0762 726 6956 exclusion phecode
528.1 Stomatitis and mucositis Digestive 0.903 0.789 – 1.03 0.141 243 1859 exclusion phecode
528.11 Stomatitis and mucositis (ulcerative) Digestive 1.01 0.786 – 1.3 0.939 69 586 exclusion phecode
528.12 Oral aphthae Digestive 0.802 0.639 – 1.01 0.0565 86 675 exclusion phecode
528.3 Cellulitis and abscess of oral soft tissues Digestive 0.973 0.741 – 1.28 0.845 57 674 exclusion phecode
528.4 Cysts of oral soft tissues Digestive 1.19 0.788 – 1.81 0.402 26 318 exclusion phecode
528.41 Cyst of the salivary gland Digestive 1.29 0.733 – 2.25 0.381 16 204 exclusion phecode
528.5 Diseases of lips Digestive 0.983 0.816 – 1.18 0.853 127 1221 exclusion phecode
528.6 Leukoplakia of oral mucosa Digestive 0.91 0.609 – 1.36 0.646 21 282 exclusion phecode
528.7 Sialolithiasis Digestive 0.88 0.605 – 1.28 0.502 30 414 exclusion phecode
529 Diseases and other conditions of the tongue Digestive 0.935 0.798 – 1.1 0.405 174 1626 exclusion phecode
529.1 Glossitis Digestive 0.928 0.658 – 1.31 0.67 37 305 exclusion phecode
529.6 Glossodynia Digestive 0.847 0.61 – 1.17 0.32 39 377 exclusion phecode
530 Diseases of esophagus Digestive 1.04 0.998 – 1.08 0.0616 4302 8072 exclusion phecode
530.1 Esophagitis, GERD and related diseases Digestive 1.04 0.999 – 1.08 0.0594 4148 8072 exclusion phecode
530.11 GERD Digestive 1.04 1 – 1.08 0.0476 4020 8071 exclusion phecode
530.12 Ulcer of esophagus Digestive 1.07 0.858 – 1.32 0.565 90 893 exclusion phecode
530.13 Barrett's esophagus Digestive 1.16 0.989 – 1.36 0.0676 165 1549 exclusion phecode
530.14 Reflux esophagitis Digestive 0.995 0.902 – 1.1 0.928 448 4436 exclusion phecode
530.15 Eosinophilic esophagitis Digestive 0.874 0.699 – 1.09 0.236 90 717 exclusion phecode
530.2 Esophageal bleeding (varices/hemorrhage) Digestive 1.21 1.04 – 1.42 0.0139 195 1432 exclusion phecode
530.3 Stricture and stenosis of esophagus Digestive 1.1 0.96 – 1.26 0.169 233 1995 exclusion phecode
530.5 Disorders of esophageal motility Digestive 0.999 0.841 – 1.19 0.994 147 1343 exclusion phecode
530.6 Diverticulum of esophagus, acquired Digestive 0.634 0.405 – 0.993 0.0463 28 222 exclusion phecode
530.7 Gastroesophageal laceration-hemorrhage syndrome Digestive 0.76 0.444 – 1.3 0.318 18 212 exclusion phecode
530.9 Heartburn Digestive 1.09 0.977 – 1.22 0.12 353 4191 exclusion phecode
531 Peptic ulcer (excl. esophageal) Digestive 1.04 0.947 – 1.13 0.445 564 4942 exclusion phecode
531.1 Hemorrhage from gastrointestinal ulcer Digestive 1.28 1.04 – 1.59 0.021 108 765 exclusion phecode
531.2 Gastric ulcer Digestive 1.02 0.913 – 1.15 0.695 333 2922 exclusion phecode
531.3 Duodenal ulcer Digestive 1.13 0.933 – 1.38 0.207 130 909 exclusion phecode
531.4 Peptic ulcer, site unspecified Digestive 1.01 0.869 – 1.17 0.894 201 1905 exclusion phecode
531.5 Gastrojejunal ulcer Digestive 0.92 0.679 – 1.25 0.592 48 429 exclusion phecode
532 Dysphagia Digestive 1.14 1.08 – 1.21 5.62e-06 1476 7680 exclusion phecode
535 Gastritis and duodenitis Digestive 1.05 0.976 – 1.13 0.19 818 7255 exclusion phecode
535.1 Acute gastritis Digestive 1.09 0.969 – 1.22 0.152 332 2902 exclusion phecode
535.2 Atrophic gastritis Digestive 1.08 0.88 – 1.32 0.47 110 896 exclusion phecode
535.6 Duodenitis Digestive 1.1 0.878 – 1.39 0.396 79 775 exclusion phecode
535.8 Other specified gastritis Digestive 0.939 0.806 – 1.09 0.414 189 1654 exclusion phecode
535.9 Gastritis and duodenitis, NOS Digestive 1.06 0.953 – 1.18 0.279 389 3390 exclusion phecode
536 Disorders of function of stomach Digestive 0.997 0.928 – 1.07 0.926 879 7690 exclusion phecode
536.3 Gastroparesis Digestive 0.998 0.863 – 1.16 0.981 216 1990 exclusion phecode
536.7
Complications of gastrostomy, colostomy and
Complications of gastrostomy, colostomy and enterostomy
 Digestive 1.13 0.947 – 1.34 0.179 150 961 exclusion phecode
536.8
Dyspepsia and other specified disorders of
Dyspepsia and other specified disorders of function of stomach
 Digestive 0.977 0.898 – 1.06 0.582 636 5805 exclusion phecode
537 Other disorders of stomach and duodenum Digestive 1.07 1 – 1.15 0.0422 965 7874 exclusion phecode
537.1 Lesions of stomach and duodenum Digestive 1.26 0.949 – 1.66 0.112 58 342 exclusion phecode
539 Bariatric surgery Digestive 1.04 0.936 – 1.16 0.462 385 4794 exclusion phecode
540 Appendiceal conditions Digestive 0.873 0.738 – 1.03 0.114 173 1503 exclusion phecode
540.1 Appendicitis Digestive 0.894 0.751 – 1.06 0.204 160 1324 exclusion phecode
540.11 Acute appendicitis Digestive 0.919 0.762 – 1.11 0.379 135 1104 exclusion phecode
550 Abdominal hernia Digestive 1 0.947 – 1.06 0.998 1593 10074 exclusion phecode
550.1 Inguinal hernia Digestive 0.9 0.807 – 1 0.0547 380 3253 exclusion phecode
550.2 Diaphragmatic hernia Digestive 1.05 0.961 – 1.14 0.301 630 6184 exclusion phecode
550.3 Femoral hernia Digestive 0.692 0.503 – 0.951 0.0233 41 282 exclusion phecode
550.4 Umbilical hernia Digestive 0.984 0.874 – 1.11 0.794 319 3118 exclusion phecode
550.5 Ventral hernia Digestive 0.955 0.875 – 1.04 0.3 576 5278 exclusion phecode
550.6 Incisional hernia Digestive 0.985 0.88 – 1.1 0.795 344 3108 exclusion phecode
555
Inflammatory bowel disease and other
Inflammatory bowel disease and other gastroenteritis and colitis
 Digestive 1.03 0.946 – 1.13 0.455 571 4207 exclusion phecode
555.1 Regional enteritis Digestive 1.02 0.908 – 1.14 0.791 351 2594 exclusion phecode
555.2 Ulcerative colitis Digestive 1.08 0.962 – 1.21 0.195 361 2578 exclusion phecode
555.21 Ulcerative colitis (chronic) Digestive 1.13 0.983 – 1.31 0.0844 234 1560 exclusion phecode
556 Ulceration of the lower GI tract Digestive 1.18 1 – 1.38 0.0435 195 1399 exclusion phecode
556.1 Ulceration of intestine Digestive 1.2 1.02 – 1.42 0.0324 173 1253 exclusion phecode
556.11
Angiodysplasia of intestine (without mention of
Angiodysplasia of intestine (without mention of hemorrhage)
 Digestive 1.47 1.1 – 1.96 0.00945 54 349 exclusion phecode
557 Intestinal malabsorption (non-celiac) Digestive 1.07 0.978 – 1.17 0.141 549 5329 exclusion phecode
557.1 Celiac disease Digestive 0.989 0.843 – 1.16 0.89 161 1354 exclusion phecode
558 Noninfectious gastroenteritis Digestive 1.06 0.988 – 1.13 0.107 1090 7308 exclusion phecode
559 Ileostomy status Digestive 1.04 0.923 – 1.17 0.514 312 2195 exclusion phecode
560 Intestinal obstruction without mention of hernia Digestive 1.07 0.999 – 1.15 0.0532 965 6253 exclusion phecode
560.1 Paralytic ileus Digestive 1.1 1 – 1.21 0.0407 502 3433 exclusion phecode
560.2 Impaction of intestine Digestive 1.01 0.842 – 1.2 0.953 148 1031 exclusion phecode
560.3 Peritoneal or intestinal adhesions Digestive 1.02 0.819 – 1.28 0.843 85 627 exclusion phecode
560.4 Other intestinal obstruction Digestive 1.07 0.972 – 1.17 0.177 533 3964 exclusion phecode
561 Symptoms involving digestive system Digestive 1.04 0.962 – 1.12 0.333 810 6123 exclusion phecode
562 Diverticulosis and diverticulitis Digestive 0.947 0.886 – 1.01 0.107 1181 5530 exclusion phecode
562.1 Diverticulosis Digestive 0.945 0.884 – 1.01 0.0961 1170 5509 exclusion phecode
562.2 Diverticulitis Digestive 0.984 0.874 – 1.11 0.796 309 3151 exclusion phecode
564 Functional digestive disorders Digestive 1.04 0.998 – 1.09 0.0593 3461 7780 exclusion phecode
564.1 Irritable Bowel Syndrome Digestive 1.06 0.993 – 1.13 0.0789 1138 6591 exclusion phecode
564.9 Personal history of diseases of digestive system Digestive 1.04 0.964 – 1.12 0.322 853 6738 exclusion phecode
565 Anal and rectal conditions Digestive 0.985 0.919 – 1.06 0.665 936 7943 exclusion phecode
565.1 Anal and rectal polyp Digestive 0.932 0.823 – 1.06 0.268 274 2640 exclusion phecode
567 Peritonitis and retroperitoneal infections Digestive 1.18 1.06 – 1.3 0.00168 430 3253 exclusion phecode
568 Other disorders of peritoneum Digestive 1.16 1.05 – 1.27 0.0026 515 4125 exclusion phecode
568.1
Peritoneal adhesions (postoperative)
Peritoneal adhesions (postoperative) (postinfection)
 Digestive 1.2 1.07 – 1.34 0.00141 370 3025 exclusion phecode
569 Other disorders of intestine Digestive 1.04 0.988 – 1.09 0.141 2118 9677 exclusion phecode
569.1 Toxic gastroenteritis and colitis Digestive 0.86 0.694 – 1.07 0.168 90 809 exclusion phecode
569.2 Gastrointestinal complications Digestive 1.09 0.99 – 1.21 0.0779 442 3619 exclusion phecode
571 Chronic liver disease and cirrhosis Digestive 1.1 1.04 – 1.18 0.00228 1140 8542 exclusion phecode
571.5 Other chronic nonalcoholic liver disease Digestive 1.09 1.02 – 1.17 0.00879 1045 8411 exclusion phecode
571.51 Cirrhosis of liver without mention of alcohol Digestive 1.35 1.2 – 1.53 1.49e-06 305 2275 exclusion phecode
571.6 Primary biliary cirrhosis Digestive 1.36 1.04 – 1.76 0.0225 64 416 exclusion phecode
571.8
Liver abscess and sequelae of chronic liver
Liver abscess and sequelae of chronic liver disease
 Digestive 1.28 1.14 – 1.44 4.27e-05 341 2097 exclusion phecode
571.81 Portal hypertension Digestive 1.26 1.09 – 1.45 0.00212 211 1230 exclusion phecode
572 Ascites (non malignant) Digestive 1.25 1.16 – 1.35 6.34e-09 800 5577 exclusion phecode
573 Other disorders of liver Digestive 1.1 1.04 – 1.16 0.00171 1459 8998 exclusion phecode
573.1 Chronic passive congestion of liver Digestive 1.42 1.13 – 1.8 0.0028 88 321 exclusion phecode
573.2 Liver replaced by transplant Digestive 1.09 0.845 – 1.4 0.512 67 626 exclusion phecode
573.3 Hepatomegaly Digestive 1.49 1.22 – 1.81 8.15e-05 118 1290 exclusion phecode
573.4 Acute and subacute necrosis of liver Digestive 1.5 1.24 – 1.82 3.63e-05 141 753 exclusion phecode
573.5 Jaundice (not of newborn) Digestive 1.1 0.979 – 1.25 0.106 320 2171 exclusion phecode
573.6
Nonspecific elevation of levels of transaminase
Nonspecific elevation of levels of transaminase or lactic acid dehydrogenase [LDH]
 Digestive 1.09 1.01 – 1.17 0.0333 794 6429 exclusion phecode
573.7 Abnormal results of function study of liver Digestive 1.08 0.997 – 1.16 0.06 794 6778 exclusion phecode
573.9 Abnormal serum enzyme levels Digestive 1.07 1.01 – 1.14 0.0338 1270 8986 exclusion phecode
574 Cholelithiasis and cholecystitis Digestive 1.08 1 – 1.16 0.0428 892 8534 exclusion phecode
574.1 Cholelithiasis Digestive 1.06 0.98 – 1.14 0.153 808 8047 exclusion phecode
574.11 Cholelithiasis with acute cholecystitis Digestive 1.13 0.919 – 1.39 0.244 105 846 exclusion phecode
574.12 Cholelithiasis with other cholecystitis Digestive 1.07 0.901 – 1.28 0.432 142 1555 exclusion phecode
574.2 Calculus of bile duct Digestive 0.934 0.816 – 1.07 0.321 245 2425 exclusion phecode
574.3 Cholecystitis without cholelithiasis Digestive 1.07 0.93 – 1.23 0.349 238 2125 exclusion phecode
575 Other biliary tract disease Digestive 1.02 0.937 – 1.1 0.698 672 5996 exclusion phecode
575.1 Cholangitis Digestive 1.04 0.855 – 1.28 0.67 120 801 exclusion phecode
575.2 Obstruction of bile duct Digestive 1.09 0.934 – 1.26 0.284 203 1444 exclusion phecode
575.6 Cholesterolosis of gallbladder Digestive 1.02 0.8 – 1.3 0.871 71 610 exclusion phecode
575.7 Other disorders of gallbladder Digestive 1.01 0.888 – 1.14 0.916 273 2632 exclusion phecode
575.8 Other disorders of biliary tract Digestive 1.07 0.959 – 1.2 0.22 362 2835 exclusion phecode
575.9
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of biliary tract
 Digestive 0.914 0.711 – 1.17 0.483 72 649 exclusion phecode
577 Diseases of pancreas Digestive 1.1 1.01 – 1.2 0.0275 579 5355 exclusion phecode
577.1 Acute pancreatitis Digestive 1.17 1.04 – 1.32 0.00793 319 3093 exclusion phecode
577.2 Chronic pancreatitis Digestive 1.15 0.966 – 1.38 0.115 136 1186 exclusion phecode
577.3 Cyst and pseudocyst of pancreas Digestive 0.964 0.806 – 1.15 0.691 138 1173 exclusion phecode
578 Gastrointestinal hemorrhage Digestive 1.07 1.01 – 1.13 0.0289 1358 9907 exclusion phecode
578.1 Hematemesis Digestive 1.08 0.917 – 1.28 0.345 157 1218 exclusion phecode
578.2 Blood in stool Digestive 1.03 0.957 – 1.11 0.416 817 6616 exclusion phecode
578.8 Hemorrhage of rectum and anus Digestive 1.02 0.94 – 1.11 0.629 668 5905 exclusion phecode
578.9 Hemorrhage of gastrointestinal tract Digestive 1.23 1.11 – 1.35 3.74e-05 482 3427 exclusion phecode
579 Other symptoms involving abdomen and pelvis Digestive 1.05 0.992 – 1.12 0.0937 1337 9171 exclusion phecode
579.2 Splenomegaly Digestive 1.12 0.97 – 1.29 0.123 220 1824 exclusion phecode
579.8 Nonspecific abnormal findings in stool contents Digestive 0.986 0.887 – 1.1 0.788 398 3194 exclusion phecode
580 Nephritis; nephrosis; renal sclerosis Genitourinary 1.29 1.15 – 1.45 1.14e-05 333 3830 exclusion phecode
580.1 Glomerulonephritis Genitourinary 1.42 1.12 – 1.82 0.00463 71 952 exclusion phecode
580.11 Proliferative glomerulonephritis Genitourinary 1.31 0.876 – 1.97 0.187 24 364 exclusion phecode
580.12 Non-proliferative glomerulonephritis Genitourinary 1.66 1.1 – 2.49 0.0153 22 282 exclusion phecode
580.13 Acute glomerulonephritis, NOS Genitourinary 1.14 0.695 – 1.86 0.61 17 144 exclusion phecode
580.14 Chronic glomerulonephritis, NOS Genitourinary 1.39 1.01 – 1.91 0.0456 44 682 exclusion phecode
580.2
Nephrotic syndrome without mention of
Nephrotic syndrome without mention of glomerulonephritis
 Genitourinary 1.44 1.06 – 1.97 0.0209 41 568 exclusion phecode
580.3
Nephritis and nephropathy without mention of
Nephritis and nephropathy without mention of glomerulonephritis
 Genitourinary 1.3 1.13 – 1.49 0.000253 226 2899 exclusion phecode
580.31
Nephritis and nephropathy in diseases
Nephritis and nephropathy in diseases classified elsewhere
 Genitourinary 1.25 1.02 – 1.53 0.0317 106 1668 exclusion phecode
580.32
Nephritis and nephropathy with pathological
Nephritis and nephropathy with pathological lesion
 Genitourinary 1.35 1.12 – 1.62 0.00133 137 1647 exclusion phecode
580.4 Renal sclerosis, NOS Genitourinary 1.21 0.96 – 1.53 0.106 76 822 exclusion phecode
585 Renal failure Genitourinary 1.3 1.23 – 1.38 3.28e-20 1706 8696 exclusion phecode
585.1 Acute renal failure Genitourinary 1.39 1.3 – 1.48 2.42e-21 1114 6489 exclusion phecode
585.2 Renal failure NOS Genitourinary 1.38 1.19 – 1.59 1.48e-05 206 1793 exclusion phecode
585.3 Chronic renal failure [CKD] Genitourinary 1.34 1.25 – 1.43 6.32e-18 1164 7456 exclusion phecode
585.31 Renal dialysis Genitourinary 1.34 1.12 – 1.59 0.00114 143 1720 exclusion phecode
585.32 End stage renal disease Genitourinary 1.37 1.17 – 1.61 8.41e-05 167 2291 exclusion phecode
585.33 Chronic Kidney Disease, Stage III Genitourinary 1.44 1.31 – 1.57 3.68e-15 613 4520 exclusion phecode
585.34 Chronic Kidney Disease, Stage IV Genitourinary 1.42 1.19 – 1.69 9.9e-05 130 1883 exclusion phecode
585.4 Chronic kidney disease, Stage I or II Genitourinary 1.42 1.24 – 1.62 1.52e-07 269 2333 exclusion phecode
586 Other disorders of the kidney and ureters Genitourinary 1.18 1.12 – 1.24 2.22e-09 1737 9646 exclusion phecode
586.1 Anatomical abnormatilies of kidney and ureters Genitourinary 1.16 0.963 – 1.4 0.118 114 1018 exclusion phecode
586.11 Small kidney Genitourinary 1.19 0.919 – 1.55 0.185 61 566 exclusion phecode
586.12 Vesicoureteral reflux Genitourinary 0.942 0.712 – 1.25 0.675 54 465 exclusion phecode
586.2 Cyst of kidney, acquired Genitourinary 1.28 1.12 – 1.46 0.000191 262 2600 exclusion phecode
586.3 Vascular disorders of kidney/hypertrophy Genitourinary 0.917 0.621 – 1.36 0.665 26 381 exclusion phecode
586.4 Stricture/obstruction of ureter Genitourinary 1.02 0.921 – 1.13 0.717 438 4112 exclusion phecode
587 Kidney replaced by transpant Genitourinary 1.16 0.979 – 1.38 0.0861 140 1929 exclusion phecode
588 Disorders resulting from impaired renal function Genitourinary 1.34 1.14 – 1.58 0.000326 165 2102 exclusion phecode
588.1 Renal osteodystrophy Genitourinary 1.21 0.849 – 1.72 0.293 31 702 exclusion phecode
588.2 Secondary hyperparathyroidism (of renal origin) Genitourinary 1.39 1.15 – 1.69 0.000703 114 1610 exclusion phecode
589 Abnormal results of function study of kidney Genitourinary 1.3 1.14 – 1.49 0.000133 243 2247 exclusion phecode
590 Pyelonephritis Genitourinary 1.06 0.958 – 1.16 0.269 481 4350 exclusion phecode
591 Urinary tract infection Genitourinary 1.06 1.01 – 1.11 0.0104 2952 8796 exclusion phecode
592 Cystitis and urethritis Genitourinary 1.01 0.94 – 1.09 0.766 853 7004 exclusion phecode
592.1 Cystitis Genitourinary 1.01 0.94 – 1.09 0.736 812 6781 exclusion phecode
592.11 Acute cystitis Genitourinary 1.07 0.975 – 1.18 0.151 491 4469 exclusion phecode
592.12 Chronic cystitis Genitourinary 0.833 0.643 – 1.08 0.166 67 634 exclusion phecode
592.13 Chronic interstitial cystitis Genitourinary 0.89 0.755 – 1.05 0.163 164 1534 exclusion phecode
592.2 Urethritis and urethral syndrome Genitourinary 0.981 0.753 – 1.28 0.887 58 590 exclusion phecode
593 Hematuria Genitourinary 1.08 1.01 – 1.15 0.0177 1167 8606 exclusion phecode
593.1 Gross hematuria Genitourinary 1.04 0.928 – 1.17 0.493 327 3154 exclusion phecode
593.2 Microscopic hematuria Genitourinary 1.02 0.895 – 1.17 0.735 259 2530 exclusion phecode
594 Urinary calculus Genitourinary 1.08 1.02 – 1.14 0.0057 1620 10668 exclusion phecode
594.1 Calculus of kidney Genitourinary 1.07 1.02 – 1.13 0.0121 1517 10628 exclusion phecode
594.2 Calculus of lower urinary tract Genitourinary 0.936 0.749 – 1.17 0.559 85 763 exclusion phecode
594.3 Calculus of ureter Genitourinary 1.08 0.959 – 1.21 0.214 333 3587 exclusion phecode
594.8 Renal colic Genitourinary 0.976 0.792 – 1.2 0.816 102 1106 exclusion phecode
595 Hydronephrosis Genitourinary 1.09 0.984 – 1.2 0.102 441 4355 exclusion phecode
596 Other disorders of bladder Genitourinary 1.01 0.936 – 1.09 0.793 760 6786 exclusion phecode
596.1 Bladder neck obstruction Genitourinary 0.927 0.722 – 1.19 0.549 67 739 exclusion phecode
596.5 Functional disorders of bladder Genitourinary 1.08 0.98 – 1.19 0.117 452 4179 exclusion phecode
597 Other disorders of urethra and urinary tract Genitourinary 1.12 0.992 – 1.27 0.0662 299 2694 exclusion phecode
597.1 Urethral stricture (not specified as infectious) Genitourinary 1.22 1.01 – 1.46 0.0352 132 1249 exclusion phecode
597.2 Urinary complications NEC Genitourinary 1.1 0.969 – 1.25 0.141 268 2385 exclusion phecode
597.8 Urethral hypermobility/ISD Genitourinary 1.01 0.743 – 1.36 0.968 53 500 exclusion phecode
598 Abnormal findings on examination of urine Genitourinary 0.905 0.607 – 1.35 0.622 29 317 exclusion phecode
598.4 Other cells and casts in urine Genitourinary 0.847 0.549 – 1.31 0.454 24 281 exclusion phecode
599 Other symptoms/disorders or the urinary system Genitourinary 1.01 0.969 – 1.05 0.676 3751 8550 exclusion phecode
599.1 Urinary obstruction Genitourinary 0.904 0.763 – 1.07 0.243 154 1356 exclusion phecode
599.2 Retention of urine Genitourinary 1.04 0.983 – 1.11 0.157 1316 7592 exclusion phecode
599.3 Dysuria Genitourinary 1.04 0.975 – 1.1 0.255 1335 7875 exclusion phecode
599.4 Urinary incontinence Genitourinary 1.01 0.949 – 1.07 0.805 1375 7498 exclusion phecode
599.5 Frequency of urination and polyuria Genitourinary 1.01 0.95 – 1.07 0.788 1366 8078 exclusion phecode
599.6 Oliguria and anuria Genitourinary 1.15 0.985 – 1.35 0.0766 191 1278 exclusion phecode
599.7 Urethral discharge Genitourinary 0.813 0.495 – 1.34 0.413 14 224 exclusion phecode
599.8 Other symptoms involving urinary system Genitourinary 1.01 0.951 – 1.07 0.754 1317 7774 exclusion phecode
599.9 Other abnormality of urination Genitourinary 0.963 0.891 – 1.04 0.343 741 6682 exclusion phecode
600 Hyperplasia of prostate Genitourinary 0.962 0.878 – 1.05 0.4 699 2150 exclusion phecode
601 Inflammatory diseases of prostate Genitourinary 0.98 0.834 – 1.15 0.806 168 1853 exclusion phecode
601.1 Prostatitis Genitourinary 0.892 0.701 – 1.13 0.35 76 832 exclusion phecode
601.11 Acute prostatitis Genitourinary 0.866 0.566 – 1.32 0.506 26 211 exclusion phecode
601.12 Chronic prostatitis Genitourinary 0.587 0.327 – 1.05 0.0735 15 182 exclusion phecode
601.3 Orchitis and epididymitis Genitourinary 1.14 0.891 – 1.46 0.296 64 754 exclusion phecode
601.4 Balanoposthitis Genitourinary 0.85 0.526 – 1.37 0.508 19 224 exclusion phecode
601.8
Other inflammatory disorders of male genital
Other inflammatory disorders of male genital organs
 Genitourinary 0.996 0.671 – 1.48 0.985 25 298 exclusion phecode
602 Other disorders of prostate Genitourinary 0.813 0.606 – 1.09 0.166 49 567 exclusion phecode
602.3 Dysplasia of prostate Genitourinary 0.655 0.308 – 1.39 0.27 8 117 exclusion phecode
603 Other disorders of testis Genitourinary 0.966 0.761 – 1.23 0.774 72 867 exclusion phecode
603.1 Hydrocele Genitourinary 0.996 0.727 – 1.36 0.978 40 559 exclusion phecode
603.2 Spermatocele Genitourinary 0.838 0.582 – 1.21 0.34 29 325 exclusion phecode
604 Disorders of penis Genitourinary 0.914 0.753 – 1.11 0.358 117 1264 exclusion phecode
604.1 Redundant prepuce and phimosis/BXO Genitourinary 1.28 0.809 – 2.02 0.292 21 263 exclusion phecode
604.3 Peyronie's disease Genitourinary 0.803 0.589 – 1.09 0.164 43 386 exclusion phecode
605 Erectile dysfunction [ED] Genitourinary 0.948 0.865 – 1.04 0.26 607 2448 exclusion phecode
608 Other disorders of male genital organs Genitourinary 1.06 0.941 – 1.19 0.336 315 2734 exclusion phecode
609 Male infertility and abnormal spermatozoa Genitourinary 0.874 0.712 – 1.07 0.198 109 923 exclusion phecode
609.1 Infertility, male Genitourinary 0.919 0.73 – 1.16 0.472 91 688 exclusion phecode
609.11 Azoospermia and oligospermia Genitourinary 0.92 0.623 – 1.36 0.676 32 229 exclusion phecode
609.2 Abnormal spermatozoa Genitourinary 0.845 0.585 – 1.22 0.37 33 331 exclusion phecode
610 Benign mammary dysplasias Genitourinary 0.958 0.899 – 1.02 0.193 1245 5773 exclusion phecode
610.1 Cystic mastopathy Genitourinary 1.04 0.946 – 1.14 0.429 543 4445 exclusion phecode
610.2 Fibroadenosis of breast Genitourinary 1.25 0.841 – 1.86 0.269 27 205 exclusion phecode
610.4 Benign neoplasm of breast Genitourinary 0.941 0.877 – 1.01 0.0905 974 5715 exclusion phecode
610.8 Other specified benign mammary dysplasias Genitourinary 1.04 0.936 – 1.15 0.501 437 3766 exclusion phecode
611 Abnormal findings on mammogram or breast exam Genitourinary 0.954 0.904 – 1.01 0.0845 1978 6161 exclusion phecode
611.1 Abnormal mammogram Genitourinary 0.954 0.899 – 1.01 0.123 1571 5362 exclusion phecode
611.11 Mammographic microcalcification Genitourinary 0.917 0.812 – 1.03 0.159 309 2737 exclusion phecode
611.3 Lump or mass in breast Genitourinary 0.979 0.918 – 1.04 0.507 1224 6154 exclusion phecode
612
Breast conditions, congenital or relating to
Breast conditions, congenital or relating to hormones
 Genitourinary 1.08 0.972 – 1.2 0.152 401 3595 exclusion phecode
612.1 Galactorrhea Genitourinary 1.05 0.815 – 1.36 0.69 73 579 exclusion phecode
612.2 Hypertrophy of breast (Gynecomastia) Genitourinary 1.11 0.98 – 1.26 0.101 264 2536 exclusion phecode
612.3 Congenital anomalies of breast Genitourinary 0.751 0.546 – 1.03 0.0778 44 323 exclusion phecode
613 Other nonmalignant breast conditions Genitourinary 0.988 0.931 – 1.05 0.689 1382 7375 exclusion phecode
613.1 Inflammatory disease of breast Genitourinary 1.08 0.933 – 1.24 0.315 214 2002 exclusion phecode
613.5 Mastodynia Genitourinary 1.01 0.924 – 1.1 0.863 614 5297 exclusion phecode
613.7 Other signs and symptoms in breast Genitourinary 1.01 0.902 – 1.14 0.805 323 2925 exclusion phecode
613.8 Other specified disorders of breast Genitourinary 1.02 0.906 – 1.15 0.762 333 3058 exclusion phecode
613.9 Breast disorder NOS Genitourinary 0.995 0.901 – 1.1 0.924 453 4086 exclusion phecode
614 Inflammatory diseases of female pelvic organs Genitourinary 0.99 0.935 – 1.05 0.738 1576 6583 exclusion phecode
614.1
Pelvic peritoneal adhesions, female
Pelvic peritoneal adhesions, female (postoperative) (postinfection)
 Genitourinary 0.951 0.797 – 1.14 0.577 137 1248 exclusion phecode
614.3 Pelvic inflammatory disease (PID) Genitourinary 1.09 0.944 – 1.27 0.233 204 1821 exclusion phecode
614.31 Acute inflammatory pelvic disease Genitourinary 1.3 0.965 – 1.75 0.0841 51 428 exclusion phecode
614.32 Chronic inflammatory pelvic disease Genitourinary 1.18 0.937 – 1.48 0.16 83 662 exclusion phecode
614.33 Pelvic inflammatory disease, NOS Genitourinary 1.03 0.839 – 1.26 0.778 104 927 exclusion phecode
614.4 Inflammatory diseases of uterus, except cervix Genitourinary 0.983 0.774 – 1.25 0.885 86 739 exclusion phecode
614.5
Inflammatory disease of cervix, vagina, and
Inflammatory disease of cervix, vagina, and vulva
 Genitourinary 0.992 0.934 – 1.05 0.795 1366 6572 exclusion phecode
614.51 Cervicitis and endocervicitis Genitourinary 1.04 0.85 – 1.27 0.699 109 1089 exclusion phecode
614.52 Vaginitis and vulvovaginitis Genitourinary 0.99 0.928 – 1.06 0.75 1187 6481 exclusion phecode
614.53 Cyst or abscess of Bartholin's gland Genitourinary 1.06 0.793 – 1.43 0.684 65 463 exclusion phecode
614.54 Abscess or ulceration of vulva Genitourinary 0.916 0.735 – 1.14 0.433 90 814 exclusion phecode
615 Endometriosis Genitourinary 0.957 0.878 – 1.04 0.315 612 5308 exclusion phecode
618 Genital prolapse Genitourinary 0.963 0.886 – 1.05 0.372 681 5448 exclusion phecode
618.1 Prolapse of vaginal walls Genitourinary 0.906 0.816 – 1.01 0.0638 425 3591 exclusion phecode
618.2 Uterine/Uterovaginal prolapse Genitourinary 0.892 0.753 – 1.06 0.185 160 1360 exclusion phecode
618.5 Prolapse of vaginal vault after hysterectomy Genitourinary 0.974 0.776 – 1.22 0.822 90 720 exclusion phecode
618.6 Vaginal enterocele, congenital or acquired Genitourinary 1.04 0.864 – 1.25 0.693 143 1241 exclusion phecode
619 Noninflammatory female genital disorders Genitourinary 0.967 0.921 – 1.02 0.192 2336 6197 exclusion phecode
619.1
Noninflammatory disorders of ovary, fallopian
Noninflammatory disorders of ovary, fallopian tube, and broad ligament
 Genitourinary 1.08 0.981 – 1.18 0.12 546 4611 exclusion phecode
619.2 Disorders of uterus, NEC Genitourinary 0.982 0.854 – 1.13 0.799 216 2102 exclusion phecode
619.3 Noninflammatory disorders of cervix Genitourinary 1.05 0.906 – 1.23 0.494 193 1743 exclusion phecode
619.4 Noninflammatory disorders of vagina Genitourinary 0.988 0.924 – 1.06 0.733 1079 6147 exclusion phecode
619.5 Noninflammatory disorders of vulva and perineum Genitourinary 1.01 0.914 – 1.12 0.823 435 3921 exclusion phecode
620 Dysplasia of female genital organs Genitourinary 1.06 0.891 – 1.27 0.502 142 1444 exclusion phecode
620.1 Dysplasia of cervix Genitourinary 1.01 0.801 – 1.28 0.923 85 752 exclusion phecode
621 Endometrial hyperplasia Genitourinary 1.2 0.984 – 1.47 0.071 113 1462 exclusion phecode
622 Polyp of female genital organs Genitourinary 0.979 0.885 – 1.08 0.678 446 4693 exclusion phecode
622.1 Polyp of corpus uteri Genitourinary 0.978 0.871 – 1.1 0.71 338 3731 exclusion phecode
622.2 Mucous polyp of cervix Genitourinary 1.04 0.874 – 1.24 0.649 137 1402 exclusion phecode
623 Hypertrophy of female genital organs Genitourinary 0.969 0.857 – 1.1 0.611 302 2885 exclusion phecode
624 Symptoms involving female genital tract Genitourinary 0.979 0.899 – 1.07 0.632 650 4636 exclusion phecode
624.1 Dystrophy of female genital tract Genitourinary 0.959 0.736 – 1.25 0.759 63 547 exclusion phecode
624.2 Atrophy of female genital tract Genitourinary 0.978 0.598 – 1.6 0.929 20 160 exclusion phecode
624.9 stress incontinence, female Genitourinary 0.931 0.855 – 1.01 0.102 642 4629 exclusion phecode
625
Pain and other symptoms associated with female
Pain and other symptoms associated with female genital organs
 Genitourinary 1.01 0.956 – 1.06 0.844 2305 5715 exclusion phecode
625.1 Dyspareunia Genitourinary 0.966 0.883 – 1.06 0.453 583 4558 exclusion phecode
626
Disorders of menstruation and other abnormal
Disorders of menstruation and other abnormal bleeding from female genital tract
 Genitourinary 0.967 0.92 – 1.02 0.193 2536 5187 exclusion phecode
626.1 Irregular menstrual cycle/bleeding Genitourinary 0.984 0.931 – 1.04 0.573 1919 5064 exclusion phecode
626.11 Absent or infrequent menstruation Genitourinary 1.03 0.931 – 1.13 0.608 511 3731 exclusion phecode
626.12 Excessive or frequent menstruation Genitourinary 0.978 0.908 – 1.05 0.552 914 4623 exclusion phecode
626.13 Irregular menstrual cycle Genitourinary 1.01 0.933 – 1.09 0.867 873 4689 exclusion phecode
626.14 Irregular menstrual bleeding Genitourinary 0.999 0.9 – 1.11 0.978 430 3720 exclusion phecode
626.15 Infertility, female, associated with anovulation Genitourinary 0.995 0.853 – 1.16 0.948 196 1776 exclusion phecode
626.2 Dysmenorrhea Genitourinary 1.05 0.966 – 1.14 0.247 689 4162 exclusion phecode
626.4 Premenstrual tension syndromes Genitourinary 0.902 0.762 – 1.07 0.233 157 1389 exclusion phecode
626.8 Infertility, female Genitourinary 1.02 0.914 – 1.13 0.758 412 3103 exclusion phecode
627 Menopausal and postmenopausal disorders Genitourinary 0.938 0.879 – 1 0.0537 1319 4567 exclusion phecode
627.1 Postmenopausal bleeding Genitourinary 0.866 0.757 – 0.992 0.038 246 2497 exclusion phecode
627.2 Symptomatic menopause Genitourinary 0.923 0.855 – 0.997 0.0406 883 4098 exclusion phecode
627.21 Symptomatic artificial menopause Genitourinary 0.889 0.665 – 1.19 0.427 55 512 exclusion phecode
627.22
Need for Hormone replacement therapy
Need for Hormone replacement therapy (postmenopausal)
 Genitourinary 0.911 0.727 – 1.14 0.418 88 795 exclusion phecode
627.3 Postmenopausal atrophic vaginitis Genitourinary 0.93 0.815 – 1.06 0.281 274 2251 exclusion phecode
627.4 Premenopausal menorrhagia Genitourinary 1.04 0.863 – 1.26 0.659 119 1308 exclusion phecode
627.5 Premature menopause and other ovarian failure Genitourinary 0.985 0.814 – 1.19 0.88 122 1235 exclusion phecode
628 Ovarian cyst Genitourinary 1.01 0.937 – 1.09 0.774 852 4887 exclusion phecode
634 Miscarriage; stillbirth Pregnancy Complications 1 0.902 – 1.11 0.956 423 3512 exclusion phecode
634.1 Missed abortion/Hydatidiform mole Pregnancy Complications 0.933 0.781 – 1.11 0.445 147 1252 exclusion phecode
634.3 Ectopic pregnancy Pregnancy Complications 0.932 0.694 – 1.25 0.64 56 514 exclusion phecode
635
Hemorrhage during pregnancy; childbirth and
Hemorrhage during pregnancy; childbirth and postpartum
 Pregnancy Complications 0.925 0.822 – 1.04 0.196 345 2723 exclusion phecode
635.2
Antepartum hemorrhage, abruptio placentae, and
Antepartum hemorrhage, abruptio placentae, and placenta previa
 Pregnancy Complications 0.942 0.816 – 1.09 0.409 228 1842 exclusion phecode
635.3 Placenta previa and abruptio placenta Pregnancy Complications 1.02 0.87 – 1.2 0.795 181 1471 exclusion phecode
636
Early or threatened labor; hemorrhage in early
Early or threatened labor; hemorrhage in early pregnancy
 Pregnancy Complications 1.01 0.926 – 1.1 0.833 679 3785 exclusion phecode
636.1 Threatened premature labor Pregnancy Complications 1.11 0.972 – 1.27 0.121 254 1923 exclusion phecode
636.2 Early onset of delivery Pregnancy Complications 1.09 0.921 – 1.28 0.321 166 1411 exclusion phecode
636.3 Hemorrhage in early pregnancy Pregnancy Complications 1.04 0.913 – 1.19 0.526 259 2192 exclusion phecode
636.8 Cervical incompetence Pregnancy Complications 1.05 0.772 – 1.42 0.772 49 382 exclusion phecode
637
Short gestation; low birth weight; and fetal
Short gestation; low birth weight; and fetal growth retardation
 Pregnancy Complications 0.914 0.593 – 1.41 0.685 23 282 exclusion phecode
642
Hypertension complicating pregnancy
Hypertension complicating pregnancy, childbirth, and the puerperium
 Pregnancy Complications 1.12 0.955 – 1.32 0.16 163 3005 exclusion phecode
642.1 Preeclampsia and eclampsia Pregnancy Complications 0.96 0.772 – 1.19 0.711 89 1563 exclusion phecode
643 Excessive vomiting in pregnancy Pregnancy Complications 1.05 0.881 – 1.25 0.59 156 1333 exclusion phecode
643.1 Hyperemesis gravidarum Pregnancy Complications 1.12 0.861 – 1.45 0.41 72 586 exclusion phecode
644 Anemia during pregnancy Pregnancy Complications 0.976 0.811 – 1.17 0.793 133 1209 exclusion phecode
646 Other complications of pregnancy NEC Pregnancy Complications 1.03 0.935 – 1.14 0.527 493 3411 exclusion phecode
647
Infectious and parasitic complications
Infectious and parasitic complications affecting pregnancy
 Pregnancy Complications 1.1 0.915 – 1.33 0.309 140 1072 exclusion phecode
647.1
Infections of genitourinary tract during
Infections of genitourinary tract during pregnancy
 Pregnancy Complications 1.04 0.871 – 1.25 0.651 146 1181 exclusion phecode
647.3 Major puerperal infection Pregnancy Complications 1.1 0.768 – 1.58 0.601 35 342 exclusion phecode
649
Other conditions or status of the mother
Other conditions or status of the mother complicating pregnancy, childbirth, or the puerperium
 Pregnancy Complications 0.946 0.871 – 1.03 0.188 737 3946 exclusion phecode
649.1
Diabetes or abnormal glucose tolerance
Diabetes or abnormal glucose tolerance complicating pregnancy
 Pregnancy Complications 1.01 0.881 – 1.16 0.89 249 2433 exclusion phecode
653
Problems associated with amniotic cavity and
Problems associated with amniotic cavity and membranes
 Pregnancy Complications 1.03 0.918 – 1.15 0.639 369 2814 exclusion phecode
654.1
Abnormality of organs and soft tissues of
Abnormality of organs and soft tissues of pelvis complicating pregnancy, childbirth, or the puerperium
 Pregnancy Complications 1.2 0.981 – 1.47 0.0755 118 1049 exclusion phecode
654.2 Rhesus isoimmunization in pregnancy Pregnancy Complications 1.12 0.925 – 1.35 0.247 120 1033 exclusion phecode
655
Known or suspected fetal abnormality affecting
Known or suspected fetal abnormality affecting management of mother
 Pregnancy Complications 1.01 0.943 – 1.09 0.694 943 4628 exclusion phecode
655.1 Abnormality in fetal heart rate or rhythm Pregnancy Complications 1.01 0.901 – 1.13 0.867 358 2841 exclusion phecode
656 Other perinatal conditions of fetus or newborn Pregnancy Complications 1.09 0.984 – 1.2 0.103 493 3401 exclusion phecode
656.2 Respiratory conditions of fetus and newborn Pregnancy Complications 0.981 0.564 – 1.71 0.947 14 172 exclusion phecode
669 Complications of labor and delivery NEC Pregnancy Complications 1.03 0.936 – 1.14 0.536 507 3531 exclusion phecode
671
Venous/cerebrovascular complications embolism
Venous/cerebrovascular complications embolism in pregnancy and the puerperium
 Pregnancy Complications 0.951 0.776 – 1.17 0.632 107 986 exclusion phecode
674 Other complications of the puerperium NEC Pregnancy Complications 1.2 0.952 – 1.52 0.122 87 818 exclusion phecode
676
Other disorders of the breast associated with
Other disorders of the breast associated with childbirth and disorders of lactation
 Pregnancy Complications 0.959 0.79 – 1.16 0.669 124 988 exclusion phecode
681 Superficial cellulitis and abscess Dermatologic 1.08 1.02 – 1.14 0.0044 1731 10531 exclusion phecode
681.1 Cellulitis and abscess of fingers/toes Dermatologic 1.09 0.966 – 1.23 0.162 309 2925 exclusion phecode
681.2 Cellulitis and abscess of face/neck Dermatologic 1.03 0.896 – 1.18 0.694 238 2502 exclusion phecode
681.3 Cellulitis and abscess of arm/hand Dermatologic 1.1 1 – 1.21 0.0406 506 4931 exclusion phecode
681.5 Cellulitis and abscess of leg, except foot Dermatologic 1.09 0.997 – 1.2 0.0592 515 5059 exclusion phecode
681.6 Cellulitis and abscess of foot, toe Dermatologic 1.13 1.01 – 1.26 0.0259 410 4016 exclusion phecode
681.7 Cellulitis and abscess of trunk Dermatologic 1.12 1.02 – 1.23 0.0217 500 4202 exclusion phecode
686
Other local infections of skin and subcutaneous
Other local infections of skin and subcutaneous tissue
 Dermatologic 0.992 0.908 – 1.08 0.856 567 5546 exclusion phecode
686.1 Carbuncle and furuncle Dermatologic 1.01 0.855 – 1.2 0.87 146 1698 exclusion phecode
686.2 Impetigo Dermatologic 1.21 1 – 1.45 0.0449 138 1225 exclusion phecode
686.3 Pilonidal cyst Dermatologic 1.01 0.764 – 1.33 0.96 59 491 exclusion phecode
686.4 Pyogenic granuloma Dermatologic 1.03 0.739 – 1.44 0.858 38 431 exclusion phecode
686.5 Pyoderma Dermatologic 1.02 0.643 – 1.61 0.941 17 158 exclusion phecode
687 Symptoms affecting skin Dermatologic 0.983 0.892 – 1.08 0.729 472 4290 exclusion phecode
687.1 Rash and other nonspecific skin eruption Dermatologic 0.999 0.951 – 1.05 0.973 2030 9390 exclusion phecode
687.3 Changes in skin texture Dermatologic 1.15 0.941 – 1.4 0.174 109 1024 exclusion phecode
687.4 Disturbance of skin sensation Dermatologic 0.988 0.937 – 1.04 0.65 1738 9278 exclusion phecode
689 Disorder of skin and subcutaneous tissue NOS Dermatologic 0.98 0.936 – 1.03 0.399 2362 10427 exclusion phecode
690 Erythematosquamous dermatosis Dermatologic 0.892 0.836 – 0.951 0.00049 1136 8142 exclusion phecode
690.1 Seborrheic dermatitis Dermatologic 0.89 0.834 – 0.949 0.000393 1133 8135 exclusion phecode
691 Congenital anomalies of skin Dermatologic 0.958 0.821 – 1.12 0.58 182 1670 exclusion phecode
691.3 Congenital pigmentary anomalies of skin Dermatologic 1.08 0.745 – 1.57 0.686 31 205 exclusion phecode
694 Dyschromia and Vitiligo Dermatologic 0.954 0.867 – 1.05 0.326 496 4715 exclusion phecode
694.1 Vitiligo Dermatologic 1.21 0.849 – 1.72 0.295 38 353 exclusion phecode
694.2 Other dyschromia Dermatologic 0.911 0.823 – 1.01 0.071 439 4252 exclusion phecode
694.3 Vascular disorders of skin Dermatologic 1.54 1.06 – 2.24 0.0251 27 206 exclusion phecode
695 Erythematous conditions Dermatologic 1 0.937 – 1.07 0.991 1078 8444 exclusion phecode
695.1 Toxic erythema Dermatologic 1.19 0.739 – 1.92 0.472 20 215 exclusion phecode
695.2 Bullous dermatoses Dermatologic 1.06 0.684 – 1.64 0.798 23 172 exclusion phecode
695.3 Rosacea Dermatologic 0.871 0.787 – 0.964 0.00758 435 4589 exclusion phecode
695.4 Lupus (localized and systemic) Dermatologic 1.11 0.959 – 1.28 0.162 225 2051 exclusion phecode
695.41 Cutaneous lupus erythematosus Dermatologic 1.15 0.909 – 1.46 0.244 80 804 exclusion phecode
695.42 Systemic lupus erythematosus Dermatologic 1.1 0.952 – 1.28 0.193 219 1932 exclusion phecode
695.7 Prurigo and Lichen Dermatologic 0.975 0.803 – 1.18 0.795 128 1534 exclusion phecode
695.8 Other specified erythematous conditions Dermatologic 1.08 0.931 – 1.25 0.31 213 2079 exclusion phecode
695.81 Erythema nodosum Dermatologic 1.43 0.9 – 2.27 0.129 28 191 exclusion phecode
695.9 Unspecified erythematous condition Dermatologic 1.11 0.942 – 1.3 0.22 172 1727 exclusion phecode
696 Psoriasis and related disorders Dermatologic 1.01 0.9 – 1.13 0.912 359 3730 exclusion phecode
696.3 Pityriasis Dermatologic 1.18 0.811 – 1.71 0.392 33 325 exclusion phecode
696.4 Psoriasis Dermatologic 0.993 0.883 – 1.12 0.909 327 3442 exclusion phecode
696.41 Psoriasis vulgaris Dermatologic 0.996 0.88 – 1.13 0.943 302 3157 exclusion phecode
696.42 Psoriatic arthropathy Dermatologic 0.962 0.753 – 1.23 0.756 67 693 exclusion phecode
697 Sarcoidosis Dermatologic 1.02 0.827 – 1.26 0.84 99 837 exclusion phecode
698 Pruritus and related conditions Dermatologic 0.912 0.842 – 0.987 0.0224 725 6557 exclusion phecode
700 Corns and callosities Dermatologic 1.08 0.949 – 1.23 0.241 283 2579 exclusion phecode
701
Other hypertrophic and atrophic conditions of
Other hypertrophic and atrophic conditions of skin
 Dermatologic 0.976 0.929 – 1.03 0.347 1966 10616 exclusion phecode
701.1 Keratoderma, acquired Dermatologic 1.03 0.868 – 1.23 0.703 139 1305 exclusion phecode
701.2 Scar conditions and fibrosis of skin Dermatologic 0.954 0.873 – 1.04 0.298 563 5942 exclusion phecode
701.3 Circumscribed scleroderma Dermatologic 0.907 0.763 – 1.08 0.266 148 1518 exclusion phecode
701.4 Keloid scar Dermatologic 0.91 0.769 – 1.08 0.272 165 1836 exclusion phecode
701.5 Abnormal granulation tissue Dermatologic 0.997 0.82 – 1.21 0.978 119 1025 exclusion phecode
702
Degenerative skin conditions and other
Degenerative skin conditions and other dermatoses
 Dermatologic 0.895 0.844 – 0.948 0.000183 1491 7717 exclusion phecode
702.1 Actinic keratosis Dermatologic 0.882 0.818 – 0.951 0.00104 829 5922 exclusion phecode
702.2 Seborrheic keratosis Dermatologic 0.855 0.802 – 0.912 1.87e-06 1152 7907 exclusion phecode
702.4 Degenerative skin disorders Dermatologic 1.22 0.838 – 1.78 0.296 29 243 exclusion phecode
703 Diseases of nail, NOS Dermatologic 1.07 0.964 – 1.2 0.196 377 3593 exclusion phecode
703.1 Ingrowing nail Dermatologic 1.04 0.901 – 1.21 0.567 210 2264 exclusion phecode
704 Diseases of hair and hair follicles Dermatologic 0.975 0.909 – 1.04 0.467 942 8778 exclusion phecode
704.1 Alopecia Dermatologic 0.971 0.881 – 1.07 0.549 497 4538 exclusion phecode
704.11 Alopecia Areata Dermatologic 0.917 0.625 – 1.35 0.66 29 227 exclusion phecode
704.12 Telogen effluvium Dermatologic 0.958 0.662 – 1.39 0.819 28 224 exclusion phecode
704.2 Hirsutism Dermatologic 1.01 0.815 – 1.25 0.943 99 1230 exclusion phecode
704.8
Other specified diseases of hair and hair
Other specified diseases of hair and hair follicles
 Dermatologic 0.945 0.858 – 1.04 0.251 477 4837 exclusion phecode
705 Disorders of sweat glands Dermatologic 1.01 0.871 – 1.18 0.852 192 2097 exclusion phecode
705.1 Dyshidrosis Dermatologic 0.851 0.63 – 1.15 0.29 46 454 exclusion phecode
705.3 Hidradenitis Dermatologic 1.13 0.894 – 1.42 0.312 81 925 exclusion phecode
705.8 Hyperhidrosis Dermatologic 1.03 0.915 – 1.16 0.64 322 3188 exclusion phecode
706 Diseases of sebaceous glands Dermatologic 0.956 0.908 – 1.01 0.0929 1798 10718 exclusion phecode
706.1 Acne Dermatologic 0.958 0.895 – 1.03 0.216 1044 7426 exclusion phecode
706.2 Sebaceous cyst Dermatologic 0.954 0.882 – 1.03 0.241 721 6957 exclusion phecode
706.3 Seborrhea Dermatologic 1.18 0.689 – 2.03 0.542 15 164 exclusion phecode
706.8 Other specified diseases of sebaceous glands Dermatologic 0.946 0.845 – 1.06 0.332 356 3460 exclusion phecode
707 Chronic ulcer of skin Dermatologic 1.12 1.04 – 1.21 0.00324 782 6361 exclusion phecode
707.1 Decubitus ulcer Dermatologic 1.16 1.02 – 1.32 0.025 279 1665 exclusion phecode
707.2 Chronic ulcer of leg or foot Dermatologic 1.28 1.11 – 1.46 0.000417 230 2070 exclusion phecode
707.3 Chronic ulcer of unspecified site Dermatologic 1.08 0.98 – 1.19 0.118 459 4000 exclusion phecode
709 Diffuse diseases of connective tissue Dermatologic 0.949 0.859 – 1.05 0.306 449 4110 exclusion phecode
709.2 Sicca syndrome Dermatologic 0.846 0.71 – 1.01 0.0615 149 1324 exclusion phecode
709.3 Systemic sclerosis Dermatologic 1 0.792 – 1.27 0.986 76 643 exclusion phecode
709.5 Dermatomyositis Dermatologic 1.59 0.979 – 2.59 0.0608 20 221 exclusion phecode
709.6
Other specified diffuse diseases of connective
Other specified diffuse diseases of connective tissue
 Dermatologic 1.02 0.719 – 1.45 0.903 33 293 exclusion phecode
709.7 Unspecified diffuse connective tissue disease Dermatologic 0.974 0.862 – 1.1 0.675 292 2650 exclusion phecode
710
Osteomyelitis, periostitis, and other
Osteomyelitis, periostitis, and other infections involving bone
 Musculoskeletal 1.13 1 – 1.27 0.0461 318 2765 exclusion phecode
710.1 Osteomyelitis Musculoskeletal 1.14 1.01 – 1.29 0.033 299 2653 exclusion phecode
710.11 Acute osteomyelitis Musculoskeletal 1.15 0.962 – 1.36 0.127 139 1293 exclusion phecode
710.12 Chronic osteomyelitis Musculoskeletal 1.21 1.01 – 1.44 0.0371 135 1119 exclusion phecode
710.19 Unspecified osteomyelitis Musculoskeletal 1.14 1.01 – 1.29 0.0333 289 2522 exclusion phecode
711 Arthropathy associated with infections Musculoskeletal 1.05 0.865 – 1.28 0.614 114 918 exclusion phecode
711.1 Pyogenic arthritis Musculoskeletal 1.04 0.819 – 1.32 0.757 78 612 exclusion phecode
712 Infective connective tissue disorders Musculoskeletal 1.2 0.913 – 1.58 0.189 57 459 exclusion phecode
713
Arthropathy associated with other disorders
Arthropathy associated with other disorders classified elsewhere
 Musculoskeletal 1.11 0.874 – 1.42 0.386 68 808 exclusion phecode
713.5
Arthropathy associated with neurological
Arthropathy associated with neurological disorders
 Musculoskeletal 1.07 0.713 – 1.6 0.749 20 377 exclusion phecode
714
Rheumatoid arthritis and other inflammatory
Rheumatoid arthritis and other inflammatory polyarthropathies
 Musculoskeletal 0.955 0.872 – 1.05 0.326 547 5040 exclusion phecode
714.1 Rheumatoid arthritis Musculoskeletal 0.934 0.843 – 1.03 0.188 432 4028 exclusion phecode
714.2 Juvenile rheumatoid arthritis Musculoskeletal 0.763 0.532 – 1.1 0.143 37 298 exclusion phecode
715 Other inflammatory spondylopathies Musculoskeletal 0.952 0.837 – 1.08 0.447 267 2902 exclusion phecode
715.1 Sacroiliitis NEC Musculoskeletal 0.882 0.678 – 1.15 0.351 64 758 exclusion phecode
715.2 Ankylosing spondylitis Musculoskeletal 0.841 0.641 – 1.11 0.214 51 609 exclusion phecode
716 Other arthropathies Musculoskeletal 0.998 0.955 – 1.04 0.914 3087 9165 exclusion phecode
716.1 Unspecified polyarthropathy or polyarthritis Musculoskeletal 0.957 0.713 – 1.28 0.768 52 530 exclusion phecode
716.2 Unspecified monoarthritis Musculoskeletal 1.1 0.793 – 1.52 0.57 38 311 exclusion phecode
716.9 Arthropathy NOS Musculoskeletal 0.996 0.954 – 1.04 0.864 3068 9161 exclusion phecode
717 Polymyalgia Rheumatica Musculoskeletal 0.852 0.608 – 1.19 0.354 37 445 exclusion phecode
720 Spinal stenosis Musculoskeletal 0.993 0.92 – 1.07 0.86 770 6812 exclusion phecode
720.1 Spinal stenosis of lumbar region Musculoskeletal 1 0.916 – 1.1 0.969 554 5192 exclusion phecode
721 Spondylosis and allied disorders Musculoskeletal 1.02 0.958 – 1.08 0.547 1214 8480 exclusion phecode
721.1 Spondylosis without myelopathy Musculoskeletal 1.01 0.949 – 1.08 0.723 1130 8273 exclusion phecode
721.2 Spondylosis with myelopathy Musculoskeletal 1.15 0.981 – 1.35 0.0858 179 1899 exclusion phecode
721.8 Other allied disorders of spine Musculoskeletal 0.915 0.714 – 1.17 0.481 71 598 exclusion phecode
722 Intervertebral disc disorders Musculoskeletal 1.01 0.954 – 1.07 0.755 1531 9336 exclusion phecode
722.1 Displacement of intervertebral disc Musculoskeletal 0.983 0.916 – 1.05 0.63 899 8314 exclusion phecode
722.3 Schmorl's nodes Musculoskeletal 0.93 0.628 – 1.38 0.718 33 276 exclusion phecode
722.6 Degeneration of intervertebral disc Musculoskeletal 1.03 0.958 – 1.1 0.439 914 7775 exclusion phecode
722.7 Intervertebral disc disorder with myelopathy Musculoskeletal 1.1 0.901 – 1.34 0.352 115 1155 exclusion phecode
722.8 Postlaminectomy syndrome Musculoskeletal 1.12 0.903 – 1.39 0.299 97 942 exclusion phecode
722.9 Other and unspecified disc disorder Musculoskeletal 0.993 0.9 – 1.1 0.882 463 4907 exclusion phecode
723 Other disorders of cervical region Musculoskeletal 0.97 0.853 – 1.1 0.644 260 2499 exclusion phecode
723.1 Torticollis Musculoskeletal 0.96 0.753 – 1.22 0.741 71 635 exclusion phecode
724 Other and unspecified disorders of back Musculoskeletal 1 0.94 – 1.07 0.976 1190 8948 exclusion phecode
724.1 Disorders of sacrum Musculoskeletal 0.984 0.906 – 1.07 0.696 663 6181 exclusion phecode
724.2 Disorders of coccyx Musculoskeletal 0.996 0.835 – 1.19 0.96 143 1260 exclusion phecode
724.8 Other symptoms referable to back Musculoskeletal 0.947 0.834 – 1.08 0.399 274 2524 exclusion phecode
724.9 Other unspecified back disorders Musculoskeletal 1.02 0.92 – 1.14 0.667 403 3433 exclusion phecode
726 Peripheral enthesopathies and allied syndromes Musculoskeletal 0.955 0.912 – 1 0.0485 2572 8342 exclusion phecode
726.1 Enthesopathy Musculoskeletal 0.973 0.924 – 1.02 0.286 1958 8313 exclusion phecode
726.2 Synoviopathy Musculoskeletal 0.907 0.785 – 1.05 0.185 210 2346 exclusion phecode
726.3 Bursitis Musculoskeletal 0.961 0.869 – 1.06 0.438 442 4255 exclusion phecode
726.4 Calcaneal spur; Exostosis NOS Musculoskeletal 0.895 0.793 – 1.01 0.0727 312 2991 exclusion phecode
727 Other disorders of synovium, tendon, and bursa Musculoskeletal 0.932 0.884 – 0.982 0.00868 1845 8321 exclusion phecode
727.1 Synovitis and tenosynovitis Musculoskeletal 0.892 0.826 – 0.963 0.00355 764 7045 exclusion phecode
727.2 Bursitis disorders Musculoskeletal 0.909 0.738 – 1.12 0.369 104 1008 exclusion phecode
727.4 Ganglion and cyst of synovium, tendon, and bursa Musculoskeletal 0.973 0.872 – 1.09 0.626 371 3702 exclusion phecode
727.5 Rupture of synovium Musculoskeletal 0.857 0.689 – 1.07 0.165 97 1135 exclusion phecode
727.6 Rupture of tendon, nontraumatic Musculoskeletal 0.958 0.87 – 1.05 0.378 470 4928 exclusion phecode
727.7 Contracture of tendon (sheath) Musculoskeletal 0.987 0.846 – 1.15 0.87 192 1803 exclusion phecode
727.8 Plica syndrome Musculoskeletal 0.76 0.568 – 1.02 0.0634 52 443 exclusion phecode
728 Disorders of muscle, ligament, and fascia Musculoskeletal 1.01 0.945 – 1.07 0.845 1213 8090 exclusion phecode
728.1 Muscular calcification and ossification Musculoskeletal 0.719 0.469 – 1.1 0.132 28 197 exclusion phecode
728.2 Laxity of ligament or hypermobility syndrome Musculoskeletal 1.04 0.827 – 1.3 0.754 90 811 exclusion phecode
728.7 Fasciitis Musculoskeletal 0.886 0.814 – 0.963 0.00454 650 6215 exclusion phecode
728.71
Contracture of palmar fascia [Dupuytren's
Contracture of palmar fascia [Dupuytren's disease]
 Musculoskeletal 0.917 0.722 – 1.16 0.477 79 806 exclusion phecode
729 Other disorders of soft tissues Musculoskeletal 1.05 0.981 – 1.13 0.154 923 7263 exclusion phecode
729.1 Rheumatism, unspecified and fibrositis Musculoskeletal 1.05 0.702 – 1.57 0.811 24 201 exclusion phecode
729.3 Panniculitis Musculoskeletal 1.05 0.757 – 1.46 0.767 37 327 exclusion phecode
729.7 Nontraumatic compartment syndrome Musculoskeletal 1.36 0.866 – 2.15 0.18 24 167 exclusion phecode
731
Osteitis deformans and osteopathies associated
Osteitis deformans and osteopathies associated with other disorders classified elsewhere
 Musculoskeletal 1.11 0.798 – 1.54 0.542 36 418 exclusion phecode
732 Osteochondropathies Musculoskeletal 1.01 0.836 – 1.22 0.919 120 1214 exclusion phecode
732.1 Juvenile osteochondrosis Musculoskeletal 0.801 0.61 – 1.05 0.11 60 599 exclusion phecode
732.7 Osteochondritis dissecans Musculoskeletal 1.38 0.939 – 2.02 0.102 30 284 exclusion phecode
733 Other disorders of bone and cartilage Musculoskeletal 0.99 0.928 – 1.06 0.758 1168 7307 exclusion phecode
733.2 Cyst of bone Musculoskeletal 0.804 0.61 – 1.06 0.123 57 555 exclusion phecode
733.4 Aseptic necrosis of bone Musculoskeletal 0.896 0.755 – 1.06 0.211 151 1182 exclusion phecode
733.6 Costochondritis Musculoskeletal 0.909 0.76 – 1.09 0.294 140 1187 exclusion phecode
733.8 Malunion and nonunion of fracture Musculoskeletal 0.963 0.842 – 1.1 0.582 242 2135 exclusion phecode
733.9 Chondromalacia Musculoskeletal 1.26 0.914 – 1.75 0.156 43 318 exclusion phecode
735 Acquired foot deformities Musculoskeletal 0.995 0.925 – 1.07 0.904 844 7687 exclusion phecode
735.1 Flat foot Musculoskeletal 0.944 0.796 – 1.12 0.504 144 1567 exclusion phecode
735.2 Acquired toe deformities Musculoskeletal 0.99 0.871 – 1.13 0.876 271 2689 exclusion phecode
735.21 Hammer toe (acquired) Musculoskeletal 1.01 0.856 – 1.2 0.881 160 1581 exclusion phecode
735.23 Hallux rigidus Musculoskeletal 0.899 0.719 – 1.12 0.348 87 929 exclusion phecode
735.3 Hallux valgus (Bunion) Musculoskeletal 0.969 0.872 – 1.08 0.56 397 3780 exclusion phecode
736 Other acquired deformities of limbs Musculoskeletal 1.01 0.931 – 1.09 0.871 740 6797 exclusion phecode
736.1 Acquired deformities of forearm Musculoskeletal 1.16 0.812 – 1.65 0.417 34 240 exclusion phecode
736.2 Acquired deformities of finger Musculoskeletal 1.06 0.798 – 1.42 0.676 56 575 exclusion phecode
736.3 Acquired deformities of hip Musculoskeletal 1.37 0.944 – 1.98 0.0974 33 250 exclusion phecode
736.4 Genu valgum or varum (acquired) Musculoskeletal 0.686 0.534 – 0.881 0.00316 65 726 exclusion phecode
736.5 Acquired deformities of knee Musculoskeletal 0.785 0.597 – 1.03 0.0813 56 563 exclusion phecode
736.6 Unequal leg length (acquired) Musculoskeletal 0.879 0.714 – 1.08 0.226 103 937 exclusion phecode
737 Curvature of spine Musculoskeletal 0.97 0.88 – 1.07 0.531 494 4199 exclusion phecode
737.1 Kyphosis (acquired) Musculoskeletal 0.987 0.823 – 1.18 0.889 133 1129 exclusion phecode
737.2 Lordosis (acquired) Musculoskeletal 1.46 0.916 – 2.32 0.112 20 157 exclusion phecode
737.3 Kyphoscoliosis and scoliosis Musculoskeletal 0.957 0.859 – 1.07 0.432 399 3290 exclusion phecode
738 Other acquired musculoskeletal deformity Musculoskeletal 0.95 0.873 – 1.03 0.237 622 6129 exclusion phecode
738.4 Acquired spondylolisthesis Musculoskeletal 1.02 0.886 – 1.17 0.808 233 2324 exclusion phecode
739 Contracture of joint Musculoskeletal 1.06 0.902 – 1.25 0.468 170 1610 exclusion phecode
740 Osteoarthrosis Musculoskeletal 0.976 0.936 – 1.02 0.255 3686 9013 exclusion phecode
740.1 Osteoarthritis; localized Musculoskeletal 0.904 0.853 – 0.959 0.000805 1518 7602 exclusion phecode
740.11 Osteoarthrosis, localized, primary Musculoskeletal 0.905 0.85 – 0.964 0.00192 1297 7015 exclusion phecode
740.12 Osteoarthrosis, localized, secondary Musculoskeletal 0.828 0.711 – 0.964 0.015 195 1712 exclusion phecode
740.2 Osteoarthrosis, generalized Musculoskeletal 0.875 0.77 – 0.994 0.0402 287 2726 exclusion phecode
740.3
Osteoarthrosis involving more than one site
Osteoarthrosis involving more than one site, but not specified as generalized
 Musculoskeletal 0.985 0.774 – 1.25 0.9 79 749 exclusion phecode
740.9 Osteoarthrosis NOS Musculoskeletal 0.979 0.938 – 1.02 0.317 3501 8980 exclusion phecode
741 Symptoms and disorders of the joints Musculoskeletal 0.959 0.914 – 1.01 0.0806 2241 9837 exclusion phecode
741.1 Ankylosis of joint Musculoskeletal 0.901 0.697 – 1.16 0.427 68 701 exclusion phecode
741.2 Stiffness of joint Musculoskeletal 1 0.894 – 1.12 0.986 357 3412 exclusion phecode
741.3 Difficulty in walking Musculoskeletal 1.04 0.951 – 1.13 0.412 617 5100 exclusion phecode
741.4 Joint effusions Musculoskeletal 0.95 0.873 – 1.03 0.239 612 6415 exclusion phecode
741.5 Hemarthrosis Musculoskeletal 1.24 0.847 – 1.82 0.267 28 221 exclusion phecode
741.6 Villonodular synovitis Musculoskeletal 0.862 0.536 – 1.39 0.54 18 178 exclusion phecode
742 Derangement of joint, non-traumatic Musculoskeletal 0.945 0.89 – 1 0.0624 1294 9432 exclusion phecode
742.1 Loose body in joint Musculoskeletal 0.844 0.618 – 1.15 0.287 42 417 exclusion phecode
742.2
Pathological, developmental or recurrent
Pathological, developmental or recurrent dislocation
 Musculoskeletal 0.88 0.719 – 1.08 0.215 105 911 exclusion phecode
742.8 Articular cartilage disorder Musculoskeletal 0.826 0.634 – 1.08 0.156 66 742 exclusion phecode
742.9 Other derangement of joint Musculoskeletal 0.965 0.907 – 1.03 0.252 1213 9282 exclusion phecode
743
Osteoporosis, osteopenia and pathological
Osteoporosis, osteopenia and pathological fracture
 Musculoskeletal 0.997 0.951 – 1.05 0.915 2365 10202 exclusion phecode
743.1 Osteoporosis Musculoskeletal 1.01 0.934 – 1.09 0.854 907 4736 exclusion phecode
743.11 Osteoporosis NOS Musculoskeletal 1.01 0.937 – 1.09 0.786 902 4696 exclusion phecode
743.12 Senile osteoporosis Musculoskeletal 0.931 0.786 – 1.1 0.409 158 1078 exclusion phecode
743.13 Other specified osteoporosis Musculoskeletal 0.908 0.719 – 1.15 0.419 84 637 exclusion phecode
743.2 Pathologic fracture Musculoskeletal 1.01 0.896 – 1.14 0.849 298 2230 exclusion phecode
743.21 Pathologic fracture of vertebrae Musculoskeletal 1.18 0.978 – 1.42 0.0842 127 919 exclusion phecode
743.22 Pathologic fracture of femur Musculoskeletal 1.16 0.804 – 1.66 0.434 32 308 exclusion phecode
743.4 Stress fracture Musculoskeletal 0.949 0.788 – 1.14 0.582 125 1151 exclusion phecode
743.9
Osteopenia or other disorder of bone and
Osteopenia or other disorder of bone and cartilage
 Musculoskeletal 0.992 0.941 – 1.05 0.779 1761 9540 exclusion phecode
745 Pain in joint Musculoskeletal 0.953 0.92 – 0.989 0.00969 5453 7378 exclusion phecode
747 Cardiac and circulatory congenital anomalies Congenital Anomalies 1.06 0.983 – 1.14 0.13 833 5493 exclusion phecode
747.1 Cardiac congenital anomalies Congenital Anomalies 1.09 1.01 – 1.19 0.0358 680 4182 exclusion phecode
747.11 Cardiac shunt/ heart septal defect Congenital Anomalies 1.06 0.937 – 1.21 0.34 289 1727 exclusion phecode
747.12 Valvular heart disease/ heart chambers Congenital Anomalies 0.977 0.856 – 1.11 0.727 281 1584 exclusion phecode
747.13 Congenital anomalies of great vessels Congenital Anomalies 1.21 1.02 – 1.44 0.0334 152 899 exclusion phecode
747.2
Congenital anomalies of peripheral vascular
Congenital anomalies of peripheral vascular system
 Congenital Anomalies 1.13 0.962 – 1.34 0.133 173 1411 exclusion phecode
748 Anomalies of respiratory system, congenital Congenital Anomalies 1.47 1.02 – 2.11 0.037 35 312 exclusion phecode
749 Congenital anomalies of face and neck Congenital Anomalies 1.07 0.915 – 1.25 0.399 189 1847 exclusion phecode
749.1 Cleft palate Congenital Anomalies 0.989 0.695 – 1.41 0.953 35 362 exclusion phecode
749.2 Congenital anomalies of skull and face bones Congenital Anomalies 1.09 0.797 – 1.5 0.576 40 378 exclusion phecode
750 Digestive congenital anomalies Congenital Anomalies 1.12 0.99 – 1.28 0.072 279 2376 exclusion phecode
750.1 Upper gastrointestinal congenital anomalies Congenital Anomalies 1.02 0.832 – 1.26 0.829 105 921 exclusion phecode
750.11 Esophageal atresia/tracheoesophageal fistula Congenital Anomalies 1.09 0.775 – 1.55 0.607 36 273 exclusion phecode
750.13 Congenital anomalies of mouth/tongue Congenital Anomalies 1.01 0.717 – 1.43 0.939 31 320 exclusion phecode
750.14 Congenital anomalies of esophagus Congenital Anomalies 0.821 0.564 – 1.2 0.306 38 297 exclusion phecode
750.15 Congenital anomalies of stomach Congenital Anomalies 1.92 1.11 – 3.33 0.0194 15 110 exclusion phecode
750.2 Lower gastrointestinal congenital anomalies Congenital Anomalies 1.1 0.941 – 1.3 0.226 172 1453 exclusion phecode
750.21 Congenital anomalies of intestine Congenital Anomalies 1.17 0.945 – 1.45 0.149 96 817 exclusion phecode
750.22
Congenital anomaly of gallbladder, bile ducts
Congenital anomaly of gallbladder, bile ducts, liver, pancreas
 Congenital Anomalies 1.04 0.822 – 1.32 0.733 79 622 exclusion phecode
751 Genitourinary congenital anomalies Congenital Anomalies 1.09 1 – 1.2 0.044 564 5625 exclusion phecode
751.1 Congenital anomalies of genital organs Congenital Anomalies 1 0.865 – 1.16 0.979 200 1978 exclusion phecode
751.11 Congenital anomalies of female genital organs Congenital Anomalies 0.953 0.81 – 1.12 0.556 165 1571 exclusion phecode
751.12 Congenital anomalies of male genital organs Congenital Anomalies 1.29 0.873 – 1.92 0.199 28 329 exclusion phecode
751.2 Congenital anomalies of urinary system Congenital Anomalies 1.15 1.02 – 1.29 0.0172 339 3498 exclusion phecode
751.21 Cystic kidney disease Congenital Anomalies 1.17 1.01 – 1.35 0.0367 202 2332 exclusion phecode
751.22 Other specified congenital anomalies of kidney Congenital Anomalies 1.05 0.846 – 1.31 0.638 87 795 exclusion phecode
751.3 Obstructive genitourinary defect Congenital Anomalies 0.962 0.756 – 1.22 0.751 73 597 exclusion phecode
752 Nervous system congenital anomalies Congenital Anomalies 1.07 0.946 – 1.2 0.296 312 2934 exclusion phecode
752.1 Neural tube defects Congenital Anomalies 1.06 0.924 – 1.21 0.41 235 2287 exclusion phecode
752.11 Spina bifida Congenital Anomalies 1.03 0.812 – 1.3 0.81 72 625 exclusion phecode
752.2
Other specified congenital anomalies of nervous
Other specified congenital anomalies of nervous system
 Congenital Anomalies 1.07 0.847 – 1.34 0.589 86 754 exclusion phecode
753 Congenital anomalies of the eye Congenital Anomalies 1.18 0.869 – 1.61 0.286 39 530 exclusion phecode
753.1 Congenital cataract and lens anomalies Congenital Anomalies 1.84 1.01 – 3.34 0.0464 11 138 exclusion phecode
753.2 Congenital anomalies of posterior segment of eye Congenital Anomalies 0.839 0.518 – 1.36 0.478 17 154 exclusion phecode
754 Congenital musculoskeletal deformities of spine Congenital Anomalies 1.06 0.938 – 1.2 0.35 302 2806 exclusion phecode
754.1 Lumbosacral spondylolysis, congenital Congenital Anomalies 1.31 0.905 – 1.91 0.152 35 332 exclusion phecode
754.2 Spondylolisthesis, congenital Congenital Anomalies 1.12 0.945 – 1.33 0.19 151 1314 exclusion phecode
755 Congenital anomalies of limbs Congenital Anomalies 0.987 0.869 – 1.12 0.841 273 2436 exclusion phecode
755.1 Congenital deformities of feet Congenital Anomalies 1 0.816 – 1.23 0.976 101 1042 exclusion phecode
755.4
Congenital anomalies of upper limb, including
Congenital anomalies of upper limb, including shoulder girdle
 Congenital Anomalies 1.04 0.734 – 1.47 0.833 28 227 exclusion phecode
755.6
Other congenital anomalies of lower limb
Other congenital anomalies of lower limb, including pelvic girdle
 Congenital Anomalies 1.01 0.854 – 1.2 0.872 156 1229 exclusion phecode
755.61 Congenital hip dysplasia and deformity Congenital Anomalies 1.06 0.856 – 1.31 0.601 108 783 exclusion phecode
756 Other congenital musculoskeletal anomalies Congenital Anomalies 0.942 0.854 – 1.04 0.238 455 4000 exclusion phecode
756.1 Congenital anomalies of abdominal wall; diaphram Congenital Anomalies 0.844 0.595 – 1.2 0.341 32 239 exclusion phecode
756.2
Pectus and other congenital anomalies of
Pectus and other congenital anomalies of ribs/sternum
 Congenital Anomalies 1.08 0.752 – 1.55 0.674 32 210 exclusion phecode
756.3
Congenital anomalies of muscle, tendon, fascia
Congenital anomalies of muscle, tendon, fascia, and connective tissue
 Congenital Anomalies 0.789 0.648 – 0.96 0.0177 116 1020 exclusion phecode
756.5 Congenital osteodystrophies Congenital Anomalies 0.97 0.857 – 1.1 0.635 282 2641 exclusion phecode
757 Congenital anomalies of the integument Congenital Anomalies 0.948 0.767 – 1.17 0.624 101 916 exclusion phecode
758 Chromosomal anomalies and genetic disorders Congenital Anomalies 1.05 0.82 – 1.34 0.699 80 613 exclusion phecode
758.1 Chromosomal anomalies Congenital Anomalies 1.04 0.763 – 1.41 0.809 53 485 exclusion phecode
759 Other and unspecified congenital anomalies Congenital Anomalies 1.02 0.881 – 1.17 0.813 224 1902 exclusion phecode
759.1 Anomalies of endocrine glands, congenital Congenital Anomalies 0.841 0.544 – 1.3 0.438 24 266 exclusion phecode
760 Back pain Symptoms 0.979 0.943 – 1.02 0.274 4435 8391 exclusion phecode
761 Cervicalgia Symptoms 0.969 0.921 – 1.02 0.232 1851 10848 exclusion phecode
763
Thoracic or lumbosacral neuritis or
Thoracic or lumbosacral neuritis or radiculitis, unspecified
 Symptoms 0.98 0.911 – 1.06 0.595 816 8300 exclusion phecode
764 Sciatica Symptoms 0.988 0.919 – 1.06 0.739 847 8472 exclusion phecode
765 Cervical radiculitis Symptoms 0.929 0.837 – 1.03 0.163 419 4583 exclusion phecode
766 Neuralgia, neuritis, and radiculitis NOS Symptoms 0.975 0.918 – 1.03 0.402 1278 10134 exclusion phecode
767 Cervicocranial/Cervicobrachial syndrome Symptoms 1.2 0.874 – 1.65 0.258 36 341 exclusion phecode
769 Nonallopathic lesions NEC Symptoms 1 0.89 – 1.12 0.999 319 3123 exclusion phecode
770 Myalgia and myositis unspecified Symptoms 1.02 0.97 – 1.08 0.386 1671 9730 exclusion phecode
771 Musculoskeletal symptoms referable to limbs Symptoms 1.05 0.986 – 1.11 0.133 1255 9695 exclusion phecode
771.1 Swelling of limb Symptoms 1.08 1.02 – 1.14 0.0101 1526 9620 exclusion phecode
771.2 Cramp of limb Symptoms 1.02 0.898 – 1.17 0.723 262 2490 exclusion phecode
772 Symptoms of the muscles Symptoms 1 0.921 – 1.09 0.927 612 5456 exclusion phecode
772.1 Muscular wasting and disuse atrophy Symptoms 1.09 0.892 – 1.32 0.408 118 1098 exclusion phecode
772.2 Spasm of muscle Symptoms 1 0.927 – 1.09 0.908 695 6782 exclusion phecode
772.3 Muscle weakness Symptoms 1.06 0.977 – 1.14 0.168 744 6651 exclusion phecode
772.4 Rhabdomyolysis Symptoms 1.07 0.786 – 1.46 0.665 46 335 exclusion phecode
772.6 Facial weakness Symptoms 1.09 0.886 – 1.34 0.42 101 1103 exclusion phecode
780 Hypothermia/Chills Symptoms 1.02 0.851 – 1.21 0.868 136 1083 exclusion phecode
781
Symptoms involving nervous and musculoskeletal
Symptoms involving nervous and musculoskeletal systems
 Symptoms 0.977 0.897 – 1.06 0.593 620 6185 exclusion phecode
781.1 Loss of height Symptoms 0.675 0.457 – 0.998 0.0486 30 242 exclusion phecode
781.2 Abnormal posture Symptoms 1.67 0.971 – 2.88 0.064 14 147 exclusion phecode
782.3 Edema Symptoms 1.09 1.03 – 1.15 0.00396 1485 9747 exclusion phecode
782.6 Pallor and flushing Symptoms 1.02 0.904 – 1.16 0.716 294 3064 exclusion phecode
783 Fever of unknown origin Symptoms 1.1 1.04 – 1.15 0.000436 1781 10954 exclusion phecode
783.1 Postprocedural fever Symptoms 1.15 0.914 – 1.44 0.236 91 721 exclusion phecode
785 Abdominal pain Symptoms 1.02 0.983 – 1.06 0.309 5150 7679 exclusion phecode
788 Syncope and collapse Symptoms 1.04 0.981 – 1.11 0.178 1224 9533 exclusion phecode
789 Nausea and vomiting Symptoms 1.05 1.01 – 1.09 0.0159 3405 9397 exclusion phecode
789.1 Persistent vomiting Symptoms 1.09 0.958 – 1.24 0.192 266 2396 exclusion phecode
790 Nonspecific findings on examination of blood Symptoms 1.19 1.09 – 1.3 5.1e-05 628 5347 exclusion phecode
790.1 Elevated sedimentation rate Symptoms 1.18 0.87 – 1.59 0.29 53 598 exclusion phecode
790.6 Other abnormal blood chemistry Symptoms 1.11 1.06 – 1.17 6.09e-05 1816 10594 exclusion phecode
790.8 Elevated C-reactive protein (CRP) Symptoms 1.25 0.995 – 1.58 0.0549 80 939 exclusion phecode
790.9 Abnormal arterial blood gases Symptoms 2.13 1.41 – 3.22 0.000327 32 356 exclusion phecode
791 Gangrene Symptoms 1.38 1.1 – 1.73 0.00546 80 643 exclusion phecode
792
Abnormal Papanicolaou smear of cervix and
Abnormal Papanicolaou smear of cervix and cervical HPV
 Genitourinary 0.935 0.876 – 0.999 0.0455 1190 5293 exclusion phecode
792.1
Papanicolaou smear of cervix or vagina with
Papanicolaou smear of cervix or vagina with atypical squamous cells
 Genitourinary 0.951 0.865 – 1.05 0.306 510 4053 exclusion phecode
794
Abnormal results of other function studies
Abnormal results of other function studies (bladder, pancreas, placenta, spleen, etc)
 Symptoms 0.932 0.765 – 1.13 0.481 110 1276 exclusion phecode
795
Other and nonspecific abnormal cytological
Other and nonspecific abnormal cytological, histological and immunological findings
 Symptoms 0.987 0.917 – 1.06 0.735 861 7051 exclusion phecode
795.8 Abnormal tumor markers Symptoms 1.01 0.891 – 1.14 0.902 281 2988 exclusion phecode
795.81 Elevated carcinoembryonic antigen [CEA] Symptoms 0.93 0.554 – 1.56 0.785 17 124 exclusion phecode
795.82 Elevated cancer antigen 125 [CA 125] Symptoms 1.08 0.834 – 1.41 0.547 65 558 exclusion phecode
796 Elevated prostate specific antigen [PSA] Genitourinary 0.888 0.782 – 1.01 0.0682 285 1833 exclusion phecode
797 Shock Symptoms 1.5 1.31 – 1.72 8.21e-09 292 1256 exclusion phecode
797.1 Cardiogenic shock Symptoms 1.69 1.39 – 2.06 1.49e-07 154 465 exclusion phecode
798 Malaise and fatigue Symptoms 0.995 0.955 – 1.04 0.809 3424 9396 exclusion phecode
798.1 Chronic fatigue syndrome Symptoms 1.03 0.942 – 1.13 0.509 552 4902 exclusion phecode
800 Fracture of lower limb Injuries & Poisonings 1 0.917 – 1.09 0.988 582 5978 exclusion phecode
800.1 Fracture of neck of femur Injuries & Poisonings 1.17 0.976 – 1.39 0.0906 141 1093 exclusion phecode
800.2 Fracture of unspecified part of femur Injuries & Poisonings 1.15 0.979 – 1.34 0.0894 184 1491 exclusion phecode
800.3 Fracture of tibia and fibula Injuries & Poisonings 0.862 0.749 – 0.991 0.0369 221 2393 exclusion phecode
800.4 Fracture of patella Injuries & Poisonings 1.02 0.835 – 1.25 0.838 104 954 exclusion phecode
801 Fracture of ankle and foot Injuries & Poisonings 0.983 0.902 – 1.07 0.695 592 6409 exclusion phecode
801.1 Fracture of foot Injuries & Poisonings 0.949 0.833 – 1.08 0.434 251 3049 exclusion phecode
802 Fracture of pelvis Injuries & Poisonings 1.05 0.861 – 1.29 0.615 113 887 exclusion phecode
803 Fracture of upper limb Injuries & Poisonings 0.95 0.868 – 1.04 0.267 544 5400 exclusion phecode
803.1 Fracture of humerus Injuries & Poisonings 1.01 0.865 – 1.17 0.931 179 1775 exclusion phecode
803.2 Fracture of radius and ulna Injuries & Poisonings 0.894 0.794 – 1.01 0.0631 312 3044 exclusion phecode
803.21 Colles' fracture Injuries & Poisonings 1.06 0.834 – 1.34 0.65 76 746 exclusion phecode
803.3 Fracture of clavicle or scapula Injuries & Poisonings 0.966 0.806 – 1.16 0.712 131 1290 exclusion phecode
804 Fracture of hand or wrist Injuries & Poisonings 0.943 0.854 – 1.04 0.241 457 4343 exclusion phecode
805
Fracture of vertebral column without mention of
Fracture of vertebral column without mention of spinal cord injury
 Injuries & Poisonings 1.02 0.916 – 1.14 0.7 375 2972 exclusion phecode
807 Fracture of ribs Injuries & Poisonings 1.03 0.878 – 1.21 0.72 166 1502 exclusion phecode
809 Fracture of unspecified bones Injuries & Poisonings 1 0.934 – 1.08 0.902 828 7780 exclusion phecode
816 Cerebral laceration and contusion Injuries & Poisonings 1.3 0.674 – 2.51 0.433 9 132 exclusion phecode
817 Concussion Injuries & Poisonings 0.953 0.848 – 1.07 0.414 332 3057 exclusion phecode
818 Intracranial hemorrhage (injury) Injuries & Poisonings 1.32 0.981 – 1.78 0.0668 53 628 exclusion phecode
818.1 Subdural hemorrhage (injury) Injuries & Poisonings 1.75 0.933 – 3.29 0.0809 12 177 exclusion phecode
818.2 Subarachnoid hemorrhage (injury) Injuries & Poisonings 1.2 0.782 – 1.83 0.408 22 219 exclusion phecode
819
Skull and face fracture and other intercranial
Skull and face fracture and other intercranial injury
 Injuries & Poisonings 0.976 0.898 – 1.06 0.562 649 6266 exclusion phecode
830 Dislocation Injuries & Poisonings 0.937 0.876 – 1 0.0579 988 9764 exclusion phecode
835 Internal derangement of knee Injuries & Poisonings 0.966 0.883 – 1.06 0.455 551 6063 exclusion phecode
836 Traumatic arthropathy Injuries & Poisonings 0.987 0.819 – 1.19 0.888 116 1170 exclusion phecode
840 Sprains and strains Injuries & Poisonings 0.91 0.866 – 0.955 0.000152 2059 10465 exclusion phecode
840.1 Muscle/tendon sprain Injuries & Poisonings 0.95 0.78 – 1.16 0.613 108 1152 exclusion phecode
840.2 Rotator cuff (capsule) sprain Injuries & Poisonings 0.879 0.782 – 0.987 0.0294 315 3552 exclusion phecode
840.3 Joint/ligament sprain Injuries & Poisonings 0.875 0.812 – 0.943 0.000489 805 7704 exclusion phecode
841 Sprains and strains of back and neck Injuries & Poisonings 0.877 0.795 – 0.967 0.00864 462 4757 exclusion phecode
842 Other sprains and strains Injuries & Poisonings 0.919 0.827 – 1.02 0.112 390 4038 exclusion phecode
850 Hemorrhage or hematoma complicating a procedure Injuries & Poisonings 1.11 1.02 – 1.21 0.0173 613 4984 exclusion phecode
851
Complications of transplants and reattached
Complications of transplants and reattached limbs
 Injuries & Poisonings 1.16 1.07 – 1.25 0.000121 820 6522 exclusion phecode
853 Complication of colostomy or enterostomy Injuries & Poisonings 1.2 1 – 1.42 0.0457 147 1083 exclusion phecode
854
Complications of cardiac/vascular device
Complications of cardiac/vascular device, implant, and graft
 Injuries & Poisonings 1.21 1.11 – 1.31 7.85e-06 671 4438 exclusion phecode
855
Complication of nervous system device, implant
Complication of nervous system device, implant, and graft
 Injuries & Poisonings 1.2 0.935 – 1.55 0.15 72 754 exclusion phecode
856
Vascular complications of surgery and medical
Vascular complications of surgery and medical procedures
 Injuries & Poisonings 0.96 0.752 – 1.23 0.743 75 655 exclusion phecode
857
Mechanical complication of unspecified
Mechanical complication of unspecified genitourinary device, implant, and graft
 Injuries & Poisonings 1.05 0.952 – 1.17 0.308 437 3747 exclusion phecode
858 Complication of internal orthopedic device Injuries & Poisonings 1.02 0.943 – 1.11 0.564 644 5620 exclusion phecode
859
Complication due to other implant and internal
Complication due to other implant and internal device
 Injuries & Poisonings 1.08 0.992 – 1.17 0.0759 666 5472 exclusion phecode
860 Bone marrow or stem cell transplant Neoplasms 1.38 1.04 – 1.82 0.0233 58 442 exclusion phecode
870 Open wounds of head; neck; and trunk Injuries & Poisonings 1.11 1.04 – 1.18 0.00127 1159 9605 exclusion phecode
870.1 Open wound or laceration of eye or eyelid Injuries & Poisonings 1.19 0.817 – 1.75 0.359 33 488 exclusion phecode
870.2 Open wound of ear Injuries & Poisonings 1.15 0.797 – 1.65 0.461 33 351 exclusion phecode
870.3 Other open wound of head and face Injuries & Poisonings 1.03 0.915 – 1.16 0.628 320 3135 exclusion phecode
870.4 Open wound of nose and sinus Injuries & Poisonings 1.01 0.736 – 1.38 0.965 45 481 exclusion phecode
870.5 Open wound of lip and mouth Injuries & Poisonings 1.11 0.856 – 1.43 0.442 65 652 exclusion phecode
870.6 Open wound of neck Injuries & Poisonings 1.29 0.967 – 1.71 0.0838 53 441 exclusion phecode
870.8 Open wound of genital organs Injuries & Poisonings 1.45 1.12 – 1.89 0.00554 75 462 exclusion phecode
871 Open wounds of extremities Injuries & Poisonings 1.03 0.96 – 1.11 0.4 879 8378 exclusion phecode
871.1 Open wound of hand except finger(s) Injuries & Poisonings 0.896 0.752 – 1.07 0.217 131 1419 exclusion phecode
871.2 Open wound of finger(s) Injuries & Poisonings 1 0.881 – 1.14 0.957 247 2548 exclusion phecode
871.3 Open wound of foot except toe(s) alone Injuries & Poisonings 1.1 0.906 – 1.33 0.34 124 1132 exclusion phecode
871.4 Open wound of toe(s) Injuries & Poisonings 0.906 0.696 – 1.18 0.462 64 599 exclusion phecode
872 Traumatic amputation Injuries & Poisonings 1.35 1.1 – 1.65 0.0037 112 1162 exclusion phecode
874 Complication of amputation stump Injuries & Poisonings 1.51 1.07 – 2.14 0.0204 42 356 exclusion phecode
875 Non-healing surgical wound Injuries & Poisonings 1.1 0.937 – 1.29 0.246 173 1493 exclusion phecode
876
Posttraumatic wound infection not elsewhere
Posttraumatic wound infection not elsewhere classified
 Injuries & Poisonings 1.27 1.1 – 1.46 0.00136 219 1969 exclusion phecode
907 Injuries to the nervous system Injuries & Poisonings 1.05 0.925 – 1.18 0.47 289 2552 exclusion phecode
910 Superficial injury, infected Injuries & Poisonings 1.14 0.786 – 1.66 0.486 32 322 exclusion phecode
911 Blister Injuries & Poisonings 1.11 0.881 – 1.39 0.385 79 658 exclusion phecode
912 Insect bite Injuries & Poisonings 0.896 0.751 – 1.07 0.22 141 1339 exclusion phecode
913 Toxic effect of venom Injuries & Poisonings 0.956 0.769 – 1.19 0.687 98 883 exclusion phecode
916 Contusion Injuries & Poisonings 1.02 0.957 – 1.08 0.563 1142 10465 exclusion phecode
930 Allergic reaction to food Injuries & Poisonings 0.977 0.862 – 1.11 0.716 277 2408 exclusion phecode
931
Contact dermatitis and other eczema due to
Contact dermatitis and other eczema due to plants [except food]
 Dermatologic 0.931 0.801 – 1.08 0.35 192 1868 exclusion phecode
938 Dermatitis due to solar radiation Dermatologic 0.921 0.866 – 0.98 0.00891 1265 7528 exclusion phecode
938.1 Acute dermatitis due to solar radiation Dermatologic 0.972 0.729 – 1.3 0.845 52 611 exclusion phecode
938.2 Chronic dermatitis due to solar radiation Dermatologic 0.913 0.857 – 0.972 0.00471 1183 7353 exclusion phecode
939
Atopic/contact dermatitis due to other or
Atopic/contact dermatitis due to other or unspecified
 Dermatologic 1 0.954 – 1.06 0.879 1938 8765 exclusion phecode
939.1 Contact and allergic dermatitis of eyelid Dermatologic 0.954 0.62 – 1.47 0.83 26 239 exclusion phecode
941 Adverse reaction to serum or vaccine Injuries & Poisonings 1.18 0.873 – 1.59 0.283 47 490 exclusion phecode
942 Infusion and transfusion reaction Injuries & Poisonings 1.1 0.899 – 1.35 0.35 99 766 exclusion phecode
946 Anaphylactic shock NOS Injuries & Poisonings 0.86 0.727 – 1.02 0.0787 148 1457 exclusion phecode
947 Urticaria Dermatologic 0.935 0.84 – 1.04 0.222 384 3647 exclusion phecode
949 Allergies, other Injuries & Poisonings 1.01 0.965 – 1.06 0.594 2132 8750 exclusion phecode
952
Spinal cord injury without evidence of spinal
Spinal cord injury without evidence of spinal bone injury
 Injuries & Poisonings 1.11 0.939 – 1.32 0.22 152 1178 exclusion phecode
957 Injury to other and unspecified nerves Injuries & Poisonings 1.11 0.762 – 1.62 0.581 31 354 exclusion phecode
958
Certain early complications of trauma or
Certain early complications of trauma or procedure
 Injuries & Poisonings 1.13 1.02 – 1.26 0.0218 410 3075 exclusion phecode
958.1 Postoperative shock Injuries & Poisonings 1.46 1.15 – 1.86 0.00191 87 393 exclusion phecode
958.2 Traumatic and surgical subcutaneous emphysema Injuries & Poisonings 0.709 0.499 – 1.01 0.0547 38 264 exclusion phecode
960 Poisoning by antibiotics Injuries & Poisonings 1.15 1.07 – 1.24 0.00022 794 5812 exclusion phecode
960.1
Adverse effects of antibacterials (not
Adverse effects of antibacterials (not penicillins)
 Injuries & Poisonings 1.17 0.954 – 1.45 0.129 103 876 exclusion phecode
960.2 Allergy/adverse effect of penicillin Injuries & Poisonings 1.17 1.07 – 1.29 0.00062 541 4125 exclusion phecode
961 Poisoning by other anti-infectives Injuries & Poisonings 1.16 0.986 – 1.35 0.0747 168 1369 exclusion phecode
961.1 Poisoning/allergy of sulfonamides Injuries & Poisonings 1.19 1.06 – 1.35 0.00445 301 2674 exclusion phecode
962 Poisoning by hormones and synthetic substitutes Injuries & Poisonings 1.21 1.04 – 1.39 0.0114 216 1964 exclusion phecode
962.1
Adrenal cortical steroids causing adverse
Adrenal cortical steroids causing adverse effects in therapeutic use
 Injuries & Poisonings 1.38 1.13 – 1.69 0.00194 115 916 exclusion phecode
962.2
Insulins and antidiabetic agents causing
Insulins and antidiabetic agents causing adverse effects in therapeutic use
 Injuries & Poisonings 1.57 0.831 – 2.96 0.165 9 158 exclusion phecode
962.3
Hormones and synthetic substitutes causing
Hormones and synthetic substitutes causing adverse effects in therapeutic use
 Injuries & Poisonings 1.02 0.84 – 1.23 0.866 125 1161 exclusion phecode
963 Poisoning by primarily systemic agents Injuries & Poisonings 0.989 0.916 – 1.07 0.778 750 6135 exclusion phecode
963.1
Antineoplastic and immunosuppressive drugs
Antineoplastic and immunosuppressive drugs causing adverse effects
 Injuries & Poisonings 0.983 0.91 – 1.06 0.671 735 6014 exclusion phecode
964
Poisoning by agents primarily affecting blood
Poisoning by agents primarily affecting blood constituents
 Injuries & Poisonings 1.2 1.04 – 1.38 0.0106 245 1509 exclusion phecode
964.1 Anticoagulants causing adverse effects Injuries & Poisonings 1.24 1.07 – 1.43 0.00367 235 1444 exclusion phecode
965
Poisoning by analgesics, antipyretics, and
Poisoning by analgesics, antipyretics, and antirheumatics
 Injuries & Poisonings 1.09 0.961 – 1.23 0.183 291 2282 exclusion phecode
965.1
Opiates and related narcotics causing adverse
Opiates and related narcotics causing adverse effects in therapeutic use
 Injuries & Poisonings 1.12 1.01 – 1.23 0.0244 480 3747 exclusion phecode
965.3
Salicylates causing adverse effects in
Salicylates causing adverse effects in therapeutic use
 Injuries & Poisonings 1.13 0.767 – 1.65 0.546 28 295 exclusion phecode
966
Poisoning by anticonvulsants and
Poisoning by anticonvulsants and anti-Parkinsonism drugs
 Injuries & Poisonings 1.17 0.835 – 1.64 0.364 39 269 exclusion phecode
967
Adverse effects of sedatives or other central
Adverse effects of sedatives or other central nervous system depressants and anesthetics
 Injuries & Poisonings 1.02 0.919 – 1.14 0.666 359 3450 exclusion phecode
969 Poisoning by psychotropic agents Injuries & Poisonings 0.969 0.78 – 1.2 0.778 93 852 exclusion phecode
971
Poisoning by drugs primarily affecting the
Poisoning by drugs primarily affecting the autonomic nervous system
 Injuries & Poisonings 1.17 0.694 – 1.97 0.556 19 135 exclusion phecode
972
Poisoning by agents primarily affecting the
Poisoning by agents primarily affecting the cardiovascular system
 Injuries & Poisonings 1.55 1.23 – 1.97 0.000271 97 549 exclusion phecode
972.1
Cardiac rhythm regulators causing adverse
Cardiac rhythm regulators causing adverse effects in therapeutic use
 Injuries & Poisonings 1.41 0.938 – 2.11 0.099 38 118 exclusion phecode
972.6 Antihypertensive agents causing adverse effects Injuries & Poisonings 1.78 1.14 – 2.78 0.0113 29 186 exclusion phecode
974
Poisoning by water, mineral, and uric acid
Poisoning by water, mineral, and uric acid metabolism drugs
 Injuries & Poisonings 2 1.41 – 2.84 9.68e-05 41 217 exclusion phecode
975
Poisoning by agents primarily acting on the
Poisoning by agents primarily acting on the smooth and skeletal muscles and respiratory system
 Injuries & Poisonings 1.11 0.743 – 1.66 0.61 26 224 exclusion phecode
976
Poisoning by agents primarily affecting skin &
Poisoning by agents primarily affecting skin & mucous membrane, ophthalmological, otorhinolaryngological, & dental drugs
 Injuries & Poisonings 1.17 0.714 – 1.92 0.533 19 158 exclusion phecode
977 Personal history of allergy to medicinal agents Injuries & Poisonings 1.12 1.02 – 1.23 0.0151 522 4285 exclusion phecode
979 Adverse drug events and drug allergies Injuries & Poisonings 1.09 1.01 – 1.16 0.0178 1003 8340 exclusion phecode
980
Encounter for long-term (current) use of
Encounter for long-term (current) use of antibiotics
 Infectious Diseases 0.988 0.884 – 1.1 0.837 353 3149 exclusion phecode
985 Toxic effect of other metals Injuries & Poisonings 1.06 0.603 – 1.86 0.841 14 125 exclusion phecode
989
Toxic effect of other substances, chiefly
Toxic effect of other substances, chiefly nonmedicinal as to source
 Injuries & Poisonings 1.26 0.917 – 1.72 0.155 47 368 exclusion phecode
990 Effects radiation NOS Injuries & Poisonings 1.04 0.972 – 1.11 0.255 1060 7180 exclusion phecode
994 Sepsis and SIRS Injuries & Poisonings 1.14 1.05 – 1.23 0.00135 759 4849 exclusion phecode
994.1 Systemic inflammatory response syndrome (SIRS) Injuries & Poisonings 1.11 0.908 – 1.35 0.311 115 720 exclusion phecode
994.2 Sepsis Injuries & Poisonings 1.13 1.04 – 1.23 0.00235 717 4568 exclusion phecode
994.21 Septic shock Injuries & Poisonings 1.36 1.19 – 1.54 3.6e-06 291 1336 exclusion phecode
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