Departments of Anesthesiology and Biostatistics | University of Michigan

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Scores Type 2 diabetes UK Biobank (UKB) PheWAS analysis

Type 2 diabetes — UK Biobank (UKB) PRS PheWAS

PRS model
PRS ID exprsweb-t2d-29358691-gcst005413-prscs-ukb-20211120Legacy PRSCSPRS-CSLarge GWAS

Evaluation cohort: UK Biobank (UKB).

This page pairs the PheWAS plot with the full sortable table for the all-subject and exclusion scans.

Read the all-subject and exclusion scans separately. The combined view is only a browsing aid, and the selected-phecode panel below is only meaningful when the same phecode exists in both scans.

ExPRS exclusion definition

Exclusion cohort: individuals without Type 2 diabetes.

For this ExPRS, the exclusion sensitivity scan removes individuals with the exposure itself before rerunning the PheWAS. This is an exposure-based sensitivity analysis rather than a diagnosis-based exclusion.

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Signal overview

The plot gives a quick view of the currently visible associations. Click a point to pin its details, inspect that phecode across scans when both rows exist, or open the matching phecode detail page.

398 rows visible 17 categories
Phecode Description Category OR 95% CI P value Cases Controls Analysis Link
008 Intestinal infection Infectious Diseases 1.03 1.01 – 1.05 0.00771 8842 88430 all phecode
008.5 Bacterial enteritis Infectious Diseases 1.02 0.977 – 1.06 0.407 2718 27172 all phecode
008.52 Intestinal infection due to C. difficile Infectious Diseases 0.96 0.886 – 1.04 0.31 653 6533 all phecode
008.6 Viral Enteritis Infectious Diseases 1.03 0.96 – 1.1 0.418 862 8622 all phecode
008.7 Intestinal infection due to protozoa Infectious Diseases 1.01 0.767 – 1.33 0.95 55 550 all phecode
010 Tuberculosis Infectious Diseases 0.866 0.74 – 1.01 0.075 166 1659 all phecode
038 Septicemia Infectious Diseases 1.04 1.01 – 1.07 0.0155 4175 41776 all phecode
038.1 Gram negative septicemia Infectious Diseases 1.02 0.948 – 1.09 0.65 850 8501 all phecode
038.2 Gram positive septicemia Infectious Diseases 1 0.912 – 1.1 0.986 494 4978 all phecode
041 Bacterial infection NOS Infectious Diseases 1.04 1.02 – 1.06 6.55e-06 12017 120377 all phecode
041.1 Staphylococcus infections Infectious Diseases 1.06 1.03 – 1.1 0.000836 3128 31348 all phecode
041.2 Streptococcus infection Infectious Diseases 1.03 0.978 – 1.08 0.275 1641 16433 all phecode
041.4 E. coli Infectious Diseases 1.03 0.995 – 1.08 0.0911 2730 27319 all phecode
053 Herpes zoster Infectious Diseases 1.09 0.988 – 1.21 0.0857 411 4137 all phecode
053.1 Herpes zoster with nervous system complications Infectious Diseases 1.17 0.945 – 1.45 0.151 95 949 all phecode
054 Herpes simplex Infectious Diseases 0.981 0.854 – 1.13 0.792 211 2107 all phecode
070 Viral hepatitis Infectious Diseases 1.03 0.947 – 1.12 0.498 590 5916 all phecode
070.1 Viral hepatitis A Infectious Diseases 0.991 0.778 – 1.26 0.94 69 690 all phecode
070.2 Viral hepatitis B Infectious Diseases 1.11 0.925 – 1.32 0.269 132 1330 all phecode
070.3 Viral hepatitis C Infectious Diseases 1.02 0.903 – 1.16 0.72 255 2568 all phecode
070.4 Chronic hepatitis Infectious Diseases 1.07 0.948 – 1.21 0.274 276 2767 all phecode
070.9 Hepatitis NOS Infectious Diseases 1.11 1 – 1.22 0.0426 428 4287 all phecode
071 Human immunodeficiency virus [HIV] disease Infectious Diseases 0.888 0.75 – 1.05 0.166 147 1467 all phecode
071.1 HIV infection, symptomatic Infectious Diseases 0.85 0.702 – 1.03 0.0939 117 1168 all phecode
078 Viral warts & HPV Infectious Diseases 1.1 1.03 – 1.17 0.00396 1004 10036 all phecode
079 Viral infection Infectious Diseases 1.02 0.98 – 1.06 0.355 2769 27694 all phecode
079.1 Varicella infection Infectious Diseases 1.02 0.802 – 1.3 0.86 64 640 all phecode
080 Postoperative infection Infectious Diseases 1.02 0.992 – 1.05 0.147 4473 44775 all phecode
081
Infection/inflammation of internal prosthetic
Infection/inflammation of internal prosthetic device; implant; and graft
 Infectious Diseases 1.04 0.997 – 1.08 0.0692 2477 24765 all phecode
090
Sexually transmitted infections (not HIV or
Sexually transmitted infections (not HIV or hepatitis)
 Infectious Diseases 1.08 0.846 – 1.38 0.536 71 709 all phecode
1000 Burns Injuries & Poisonings 1.03 0.942 – 1.12 0.559 578 5796 all phecode
1001 Foreign body injury Injuries & Poisonings 0.994 0.937 – 1.05 0.839 1199 12007 all phecode
1002
Symptoms concerning nutrition, metabolism, and
Symptoms concerning nutrition, metabolism, and development
 Injuries & Poisonings 1.01 0.983 – 1.04 0.441 5480 54819 all phecode
1004
Other signs and symptoms involving emotional
Other signs and symptoms involving emotional state
 Injuries & Poisonings 0.94 0.835 – 1.06 0.31 300 2997 all phecode
1005 Other symptoms Injuries & Poisonings 0.983 0.931 – 1.04 0.546 1444 14422 all phecode
1006 Crushing injury Injuries & Poisonings 0.946 0.834 – 1.07 0.387 256 2558 all phecode
1007 Injury to blood vessels Injuries & Poisonings 1.04 0.917 – 1.18 0.541 256 2559 all phecode
1008 Crushing or internal injury to organs Injuries & Poisonings 1.02 0.961 – 1.09 0.459 1013 10132 all phecode
1009 Injury, NOS Injuries & Poisonings 1 0.982 – 1.03 0.708 8482 84911 all phecode
1010 Other tests Injuries & Poisonings 1.05 1.02 – 1.08 0.000215 5945 59512 all phecode
1011 Complications of surgical and medical procedures Injuries & Poisonings 1.02 1 – 1.04 0.041 9152 91588 all phecode
1012 Late effect Injuries & Poisonings 1.06 0.874 – 1.3 0.534 105 1057 all phecode
1013 Asphyxia and hypoxemia Injuries & Poisonings 0.994 0.887 – 1.11 0.923 316 3168 all phecode
1014 Effects of heat, cold and air pressure Injuries & Poisonings 0.93 0.73 – 1.19 0.559 66 659 all phecode
1015 Effects of other external causes Injuries & Poisonings 1.04 1 – 1.07 0.0278 4226 42294 all phecode
1019
Other ill-defined and unknown causes of
Other ill-defined and unknown causes of morbidity and mortality
 Injuries & Poisonings 1.03 1.02 – 1.05 0.000127 15895 159019 all phecode
110 Dermatophytosis / Dermatomycosis Infectious Diseases 1.09 0.96 – 1.23 0.191 279 2810 all phecode
110.1 Dermatophytosis Infectious Diseases 1.08 0.95 – 1.22 0.246 273 2750 all phecode
110.11 Dermatophytosis of nail Infectious Diseases 1.12 0.885 – 1.41 0.356 74 756 all phecode
110.12 Althete's foot Infectious Diseases 0.986 0.829 – 1.17 0.874 141 1410 all phecode
112 Candidiasis Infectious Diseases 1.03 0.987 – 1.08 0.167 2126 21275 all phecode
117 Mycoses Infectious Diseases 1.02 0.905 – 1.16 0.711 272 2719 all phecode
117.4 Aspergillosis Infectious Diseases 0.952 0.813 – 1.12 0.544 165 1650 all phecode
130 Spirochetal infection Infectious Diseases 0.905 0.718 – 1.14 0.397 80 800 all phecode
133 Arthropod-borne diseases Infectious Diseases 1.17 0.903 – 1.53 0.23 69 689 all phecode
134 Helminthiases Infectious Diseases 0.975 0.815 – 1.17 0.785 127 1267 all phecode
134.1 Intestinal helminthiases Infectious Diseases 1.02 0.837 – 1.23 0.868 106 1058 all phecode
136 Other infectious and parasitic diseases Infectious Diseases 1.13 0.984 – 1.3 0.0832 205 2050 all phecode
145 Cancer of mouth Neoplasms 1.07 0.989 – 1.16 0.0888 642 6415 all phecode
145.2 Cancer of tongue Neoplasms 1.09 0.973 – 1.22 0.135 310 3096 all phecode
145.3 Cancer of major salivary glands Neoplasms 0.975 0.799 – 1.19 0.805 105 1049 all phecode
145.5 Cancer of the mouth floor Neoplasms 0.94 0.711 – 1.24 0.662 54 539 all phecode
149 Cancer of larynx, pharynx, nasal cavities Neoplasms 1.05 0.972 – 1.14 0.2 635 6342 all phecode
149.1 Cancer of oropharynx Neoplasms 1 0.884 – 1.14 0.949 252 2517 all phecode
149.4 Cancer of larynx Neoplasms 1.11 0.979 – 1.26 0.103 265 2640 all phecode
149.9 Cancer of of nasal cavities Neoplasms 1.02 0.788 – 1.33 0.86 57 570 all phecode
150 Cancer of esophagus Neoplasms 0.937 0.87 – 1.01 0.0847 762 7630 all phecode
151 Cancer of stomach Neoplasms 0.987 0.907 – 1.08 0.77 569 5696 all phecode
153 Colorectal cancer Neoplasms 1.01 0.979 – 1.04 0.555 4580 45799 all phecode
153.2 Colon cancer Neoplasms 0.995 0.959 – 1.03 0.778 3105 31046 all phecode
153.3
Malignant neoplasm of rectum, rectosigmoid
Malignant neoplasm of rectum, rectosigmoid junction, and anus
 Neoplasms 1.02 0.979 – 1.07 0.305 2164 21640 all phecode
155 Cancer of liver and intrahepatic bile duct Neoplasms 1.07 0.963 – 1.18 0.211 400 4008 all phecode
155.1 Malignant neoplasm of liver, primary Neoplasms 1.2 1.02 – 1.42 0.0283 158 1580 all phecode
157 Pancreatic cancer Neoplasms 1.09 1.01 – 1.18 0.0245 659 6582 all phecode
158
Neoplasm of unspecified nature of digestive
Neoplasm of unspecified nature of digestive system
 Neoplasms 0.971 0.912 – 1.03 0.367 1063 10635 all phecode
159
Malignant neoplasm of other and ill-defined
Malignant neoplasm of other and ill-defined sites within the digestive organs and peritoneum
 Neoplasms 1.02 0.988 – 1.04 0.275 5567 55694 all phecode
159.2
Malignant neoplasm of small intestine
Malignant neoplasm of small intestine, including duodenum
 Neoplasms 1.05 0.9 – 1.21 0.563 190 1900 all phecode
159.3
Malignant neoplasm of gallbladder and
Malignant neoplasm of gallbladder and extrahepatic bile ducts
 Neoplasms 1.05 0.905 – 1.21 0.535 205 2048 all phecode
159.4
Malignant neoplasm of retroperitoneum and
Malignant neoplasm of retroperitoneum and peritoneum
 Neoplasms 1.1 0.95 – 1.28 0.198 193 1925 all phecode
164 Cancer of intrathoracic organs Neoplasms 1.31 1 – 1.7 0.0485 60 600 all phecode
165 Cancer within the respiratory system Neoplasms 1.04 0.999 – 1.08 0.056 2824 28235 all phecode
165.1 Cancer of bronchus; lung Neoplasms 1.02 0.981 – 1.07 0.278 2230 22307 all phecode
170 Cancer of bone and connective tissue Neoplasms 1.07 0.97 – 1.18 0.178 437 4364 all phecode
170.1 Bone cancer Neoplasms 1.13 0.947 – 1.34 0.177 131 1309 all phecode
170.2 Cancer of connective tissue Neoplasms 1.06 0.95 – 1.19 0.281 331 3303 all phecode
172 Skin cancer Neoplasms 0.984 0.967 – 1 0.0753 13495 134987 all phecode
172.1 Melanomas of skin, dx or hx Neoplasms 0.968 0.93 – 1.01 0.107 2681 26792 all phecode
172.11 Melanomas of skin Neoplasms 0.97 0.933 – 1.01 0.135 2713 27112 all phecode
172.2 Other non-epithelial cancer of skin Neoplasms 0.982 0.963 – 1 0.077 11000 110056 all phecode
172.3 Carcinoma in situ of skin Neoplasms 0.996 0.921 – 1.08 0.931 666 6656 all phecode
173 Neoplasm of uncertain behavior of skin Neoplasms 0.935 0.804 – 1.09 0.388 181 1818 all phecode
174 Breast cancer Neoplasms 1.01 0.994 – 1.03 0.188 12686 126597 all phecode
174.1 Breast cancer [female] Neoplasms 1.01 0.994 – 1.03 0.185 12476 124506 all phecode
174.11 Malignant neoplasm of female breast Neoplasms 1.02 0.997 – 1.04 0.105 11757 117502 all phecode
174.3 Neoplasm of uncertain behavior of breast Neoplasms 1.15 0.943 – 1.39 0.171 115 1148 all phecode
175 Acquired absence of breast Neoplasms 0.991 0.95 – 1.03 0.679 2400 24010 all phecode
180 Cervical cancer and dysplasia Neoplasms 0.975 0.933 – 1.02 0.267 2174 21747 all phecode
180.1 Cervical cancer Neoplasms 0.969 0.856 – 1.1 0.619 272 2720 all phecode
180.3
Cervical intraepithelial neoplasia [CIN]
Cervical intraepithelial neoplasia [CIN] [Cervical dysplasia]
 Neoplasms 0.98 0.937 – 1.02 0.372 2078 20784 all phecode
182 Malignant neoplasm of uterus Neoplasms 0.993 0.938 – 1.05 0.823 1282 12836 all phecode
184 Cancer of other female genital organs Neoplasms 1.05 0.997 – 1.11 0.064 1378 13772 all phecode
184.1
Malignant neoplasm of ovary and other uterine
Malignant neoplasm of ovary and other uterine adnexa
 Neoplasms 1.05 0.984 – 1.12 0.139 967 9667 all phecode
184.11 Malignant neoplasm of ovary Neoplasms 1.07 0.999 – 1.14 0.0534 939 9387 all phecode
184.2
Cancer of other female genital organs
Cancer of other female genital organs (excluding uterus and ovary)
 Neoplasms 1.01 0.9 – 1.14 0.821 305 3049 all phecode
185 Cancer of prostate Neoplasms 1.01 0.987 – 1.04 0.321 5974 58812 all phecode
187 Cancer of other male genital organs Neoplasms 0.995 0.902 – 1.1 0.914 449 4485 all phecode
187.1
Malignant neoplasm of unspecified male genital
Malignant neoplasm of unspecified male genital organ
 Neoplasms 0.922 0.723 – 1.18 0.512 70 700 all phecode
187.2 Malignant neoplasm of testis Neoplasms 0.985 0.871 – 1.11 0.814 287 2868 all phecode
187.8
Neoplasm of uncertain behavior of male genital
Neoplasm of uncertain behavior of male genital organs
 Neoplasms 1.07 0.881 – 1.31 0.484 110 1098 all phecode
189
Cancer of urinary organs (incl. kidney and
Cancer of urinary organs (incl. kidney and bladder)
 Neoplasms 1.04 1.01 – 1.07 0.0157 4160 41604 all phecode
189.1 Cancer of kidney and renal pelvis Neoplasms 1.03 0.968 – 1.1 0.34 1073 10723 all phecode
189.11 Malignant neoplasm of kidney, except pelvis Neoplasms 1.04 0.976 – 1.11 0.228 1033 10324 all phecode
189.12 Malignant neoplasm of renal pelvis Neoplasms 0.865 0.668 – 1.12 0.272 66 660 all phecode
189.2 Cancer of bladder Neoplasms 1.07 1.02 – 1.11 0.00257 2409 24113 all phecode
189.21 Malignant neoplasm of bladder Neoplasms 1.07 1.02 – 1.11 0.00415 2142 21447 all phecode
189.4 Malignant neoplasm of other urinary organs Neoplasms 0.811 0.679 – 0.969 0.0209 144 1439 all phecode
190 Cancer of eye Neoplasms 0.935 0.801 – 1.09 0.393 176 1758 all phecode
191
Manlignant and unknown neoplasms of brain and
Manlignant and unknown neoplasms of brain and nervous system
 Neoplasms 0.987 0.914 – 1.07 0.749 689 6879 all phecode
191.1 Cancer of brain and nervous system Neoplasms 0.996 0.914 – 1.09 0.932 566 5650 all phecode
191.11 Cancer of brain Neoplasms 1 0.915 – 1.09 0.985 525 5240 all phecode
193 Thyroid cancer Neoplasms 1.07 0.961 – 1.2 0.214 346 3466 all phecode
194 Cancer of other endocrine glands Neoplasms 0.883 0.716 – 1.09 0.247 95 949 all phecode
195 Cancer, suspected or other Neoplasms 1.02 1.01 – 1.04 0.0028 16967 165463 all phecode
195.1 Malignant neoplasm, other Neoplasms 1.02 1.01 – 1.04 0.00761 16267 159497 all phecode
197 Chemotherapy Neoplasms 1.03 1.02 – 1.05 1.85e-05 21433 213213 all phecode
198 Secondary malignant neoplasm Neoplasms 1.02 1 – 1.05 0.024 9552 95503 all phecode
198.1 Secondary malignancy of lymph nodes Neoplasms 1.01 0.984 – 1.04 0.391 5368 53670 all phecode
198.2 Secondary malignancy of respiratory organs Neoplasms 1 0.962 – 1.05 0.853 2267 22670 all phecode
198.3
Secondary malignant neoplasm of digestive
Secondary malignant neoplasm of digestive systems
 Neoplasms 0.981 0.931 – 1.03 0.472 1549 15496 all phecode
198.4 Secondary malignant neoplasm of liver Neoplasms 1.01 0.974 – 1.05 0.524 2665 26648 all phecode
198.5 Secondary malignancy of brain/spine Neoplasms 1.02 0.951 – 1.1 0.569 848 8473 all phecode
198.6 Secondary malignancy of bone Neoplasms 1.06 1.01 – 1.11 0.00935 2161 21600 all phecode
198.7 Secondary malignant neoplasm of skin Neoplasms 0.952 0.82 – 1.1 0.515 188 1890 all phecode
199 Neoplasm of uncertain behavior Neoplasms 1.01 0.952 – 1.06 0.85 1432 14313 all phecode
199.4 Neurofibromatosis Neoplasms 0.937 0.761 – 1.15 0.54 95 950 all phecode
200 Myeloproliferative disease Neoplasms 1.05 0.987 – 1.12 0.114 991 9911 all phecode
200.1 Polycythemia vera Neoplasms 1.03 0.926 – 1.14 0.608 387 3867 all phecode
201 Hodgkin's disease Neoplasms 0.872 0.765 – 0.994 0.04 259 2598 all phecode
202 Cancer of other lymphoid, histiocytic tissue Neoplasms 0.985 0.944 – 1.03 0.502 2264 22709 all phecode
202.2 Non-Hodgkins lymphoma Neoplasms 0.978 0.933 – 1.03 0.375 1802 18073 all phecode
202.21 Nodular lymphoma Neoplasms 0.95 0.853 – 1.06 0.346 363 3647 all phecode
202.24 Large cell lymphoma Neoplasms 1.02 0.941 – 1.11 0.586 581 5824 all phecode
204 Leukemia Neoplasms 1.03 0.981 – 1.08 0.221 1660 16630 all phecode
204.1 Lymphoid leukemia Neoplasms 1 0.924 – 1.09 0.912 577 5784 all phecode
204.11 Lymphoid leukemia, acute Neoplasms 1.09 0.825 – 1.44 0.541 56 560 all phecode
204.12 Lymphoid leukemia, chronic Neoplasms 1 0.916 – 1.09 0.987 507 5084 all phecode
204.2 Myeloid leukemia Neoplasms 1.01 0.918 – 1.11 0.811 462 4617 all phecode
204.21 Myeloid leukemia, acute Neoplasms 0.993 0.887 – 1.11 0.9 329 3287 all phecode
204.22 Myeloid leukemia, chronic Neoplasms 1.04 0.873 – 1.24 0.663 144 1440 all phecode
204.4 Multiple myeloma Neoplasms 1.02 0.935 – 1.11 0.679 555 5560 all phecode
208 Benign neoplasm of colon Neoplasms 1.03 1.01 – 1.04 0.000543 19856 191891 all phecode
210 Benign neoplasm of lip, oral cavity, and pharynx Neoplasms 1.01 0.945 – 1.08 0.793 978 9781 all phecode
211
Benign neoplasm of other parts of digestive
Benign neoplasm of other parts of digestive system
 Neoplasms 1.06 1.03 – 1.09 3.3e-05 5243 52452 all phecode
212
Benign neoplasm of respiratory and
Benign neoplasm of respiratory and intrathoracic organs
 Neoplasms 1.02 0.912 – 1.13 0.769 347 3466 all phecode
213 Benign neoplasm of bone and articular cartilage Neoplasms 0.938 0.836 – 1.05 0.277 318 3187 all phecode
214 Lipoma Neoplasms 1.03 1 – 1.06 0.0333 6231 62346 all phecode
214.1 Lipoma of skin and subcutaneous tissue Neoplasms 1.04 1.01 – 1.07 0.00753 4585 45872 all phecode
215
Other benign neoplasm of connective and other
Other benign neoplasm of connective and other soft tissue
 Neoplasms 0.993 0.934 – 1.06 0.816 1107 11061 all phecode
216 Benign neoplasm of skin Neoplasms 0.988 0.965 – 1.01 0.308 7664 76660 all phecode
217 Vascular hamartomas and non-neoplastic nevi Neoplasms 1.03 0.946 – 1.12 0.516 632 6313 all phecode
217.1 Nevus, non-neoplastic Neoplasms 1.02 0.933 – 1.1 0.728 595 5943 all phecode
218 Benign neoplasm of uterus Neoplasms 1.03 1.01 – 1.05 0.00824 10023 100200 all phecode
218.1 Uterine leiomyoma Neoplasms 1.03 1.01 – 1.05 0.00981 10241 102376 all phecode
218.2 Other benign neoplasm of uterus Neoplasms 1.02 0.911 – 1.13 0.766 355 3548 all phecode
220 Benign neoplasm of ovary Neoplasms 1.04 0.981 – 1.09 0.209 1445 14483 all phecode
221 Benign neoplasm of other female genital organs Neoplasms 1.02 0.89 – 1.18 0.739 220 2196 all phecode
222 Benign neoplasm of male genital organs Neoplasms 0.966 0.82 – 1.14 0.674 160 1600 all phecode
223
Benign neoplasm of kidney and other urinary
Benign neoplasm of kidney and other urinary organs
 Neoplasms 1.04 0.888 – 1.21 0.657 173 1729 all phecode
224 Benign neoplasm of eye Neoplasms 0.999 0.833 – 1.2 0.993 129 1299 all phecode
224.1 Benign neoplasm of eye, uveal Neoplasms 1.08 0.839 – 1.39 0.553 67 680 all phecode
225
Benign neoplasm of brain and other parts of
Benign neoplasm of brain and other parts of nervous system
 Neoplasms 1.03 0.955 – 1.11 0.464 816 8155 all phecode
225.1
Benign neoplasm of brain, cranial nerves
Benign neoplasm of brain, cranial nerves, meninges
 Neoplasms 1.02 0.944 – 1.1 0.644 775 7756 all phecode
225.2 Benign neoplasm of spinal cord, meninges Neoplasms 0.987 0.759 – 1.28 0.92 59 589 all phecode
226 Benign neoplasm of thyroid glands Neoplasms 0.998 0.88 – 1.13 0.973 266 2664 all phecode
227
Benign neoplasm of other endocrine glands and
Benign neoplasm of other endocrine glands and related structures
 Neoplasms 1.05 0.976 – 1.12 0.203 861 8635 all phecode
227.1 Benign neoplasm of adrenal gland Neoplasms 1.12 0.961 – 1.3 0.15 186 1857 all phecode
227.2 Benign neoplasm of parathyroid gland Neoplasms 0.986 0.885 – 1.1 0.805 371 3709 all phecode
227.3
Benign neoplasm of pituitary gland and
Benign neoplasm of pituitary gland and craniopharyngeal duct (pouch)
 Neoplasms 1.09 0.973 – 1.23 0.134 309 3114 all phecode
228 Hemangioma and lymphangioma, any site Neoplasms 0.99 0.941 – 1.04 0.701 1596 15966 all phecode
229 Benign neoplasm of unspecified sites Neoplasms 1.02 0.974 – 1.06 0.465 2397 23955 all phecode
240 Simple and unspecified goiter Endocrine/metabolic 1.03 0.948 – 1.12 0.473 600 6016 all phecode
241 Nontoxic nodular goiter Endocrine/metabolic 1.01 0.95 – 1.08 0.735 1107 11092 all phecode
241.1 Nontoxic uninodular goiter Endocrine/metabolic 1.04 0.948 – 1.14 0.398 471 4706 all phecode
241.2 Nontoxic multinodular goiter Endocrine/metabolic 0.978 0.904 – 1.06 0.59 676 6784 all phecode
242 Thyrotoxicosis with or without goiter Endocrine/metabolic 1.1 1.05 – 1.15 0.000125 1854 18531 all phecode
242.1 Graves' disease Endocrine/metabolic 1.08 0.983 – 1.19 0.11 456 4553 all phecode
242.2 Toxic multinodular goiter Endocrine/metabolic 1.12 0.909 – 1.39 0.28 91 910 all phecode
242.3 Exophthalmos Endocrine/metabolic 0.927 0.779 – 1.1 0.389 138 1379 all phecode
244 Hypothyroidism Endocrine/metabolic 1.05 1.03 – 1.07 1.09e-08 14590 145053 all phecode
244.1 Secondary hypothyroidism Endocrine/metabolic 1.06 0.995 – 1.13 0.0697 1108 11079 all phecode
244.2 Acquired hypothyroidism Endocrine/metabolic 0.939 0.765 – 1.15 0.544 101 1010 all phecode
244.4 Hypothyroidism NOS Endocrine/metabolic 1.05 1.03 – 1.07 1.53e-08 13918 138926 all phecode
245 Thyroiditis Endocrine/metabolic 0.932 0.825 – 1.05 0.256 288 2877 all phecode
245.2 Chronic thyroiditis Endocrine/metabolic 0.974 0.848 – 1.12 0.714 218 2177 all phecode
245.21 Chronic lymphocytic thyroiditis Endocrine/metabolic 0.967 0.839 – 1.11 0.644 210 2097 all phecode
246 Other disorders of thyroid Endocrine/metabolic 1.05 0.949 – 1.17 0.33 397 3975 all phecode
250 Diabetes mellitus Endocrine/metabolic 1.47 1.45 – 1.49 9.5e-552 19787 186006 all phecode
250.1 Type 1 diabetes Endocrine/metabolic 1.43 1.38 – 1.49 5.25e-71 2758 27621 all phecode
250.11 Type 1 diabetes with ketoacidosis Endocrine/metabolic 1.35 1.17 – 1.55 2.84e-05 239 2389 all phecode
250.12 Type 1 diabetes with renal manifestations Endocrine/metabolic 1.32 1.05 – 1.66 0.0174 76 770 all phecode
250.13 Type 1 diabetes with ophthalmic manifestations Endocrine/metabolic 1.48 1.35 – 1.63 1.13e-15 473 4744 all phecode
250.14 Type 1 diabetes with neurological manifestations Endocrine/metabolic 1.38 1.17 – 1.63 0.000118 160 1610 all phecode
250.2 Type 2 diabetes Endocrine/metabolic 1.49 1.47 – 1.52 4.51e-543 17831 170202 all phecode
250.21 Type 2 diabetes with ketoacidosis Endocrine/metabolic 1.38 1.13 – 1.68 0.00156 104 1050 all phecode
250.22 Type 2 diabetes with renal manifestations Endocrine/metabolic 1.42 1.23 – 1.64 2.22e-06 200 2018 all phecode
250.23 Type 2 diabetes with ophthalmic manifestations Endocrine/metabolic 1.66 1.56 – 1.78 6.23e-50 986 9907 all phecode
250.24 Type 2 diabetes with neurological manifestations Endocrine/metabolic 1.67 1.52 – 1.83 2.56e-26 503 5066 all phecode
250.4 Abnormal glucose Endocrine/metabolic 1.31 1.21 – 1.42 2.17e-11 680 6827 all phecode
250.41 Impaired fasting glucose Endocrine/metabolic 1.33 1.17 – 1.51 8.64e-06 265 2659 all phecode
250.42 Other abnormal glucose Endocrine/metabolic 1.3 1.18 – 1.44 2.35e-07 416 4178 all phecode
250.5 Glycosuria or Acetonuria Endocrine/metabolic 1.33 1.11 – 1.59 0.00214 131 1308 all phecode
250.6 Polyneuropathy in diabetes Endocrine/metabolic 1.57 1.4 – 1.76 4.77e-15 349 3495 all phecode
250.7 Diabetic retinopathy Endocrine/metabolic 1.52 1.44 – 1.61 6.74e-47 1329 13335 all phecode
251.1 Hypoglycemia Endocrine/metabolic 1.43 1.34 – 1.54 6.53e-25 932 9370 all phecode
252 Disorders of parathyroid gland Endocrine/metabolic 1.03 0.958 – 1.1 0.44 873 8719 all phecode
252.1 Hyperparathyroidism Endocrine/metabolic 0.999 0.927 – 1.08 0.974 781 7802 all phecode
252.2 Hypoparathyroidism Endocrine/metabolic 1.2 1.01 – 1.42 0.0369 142 1418 all phecode
253
Disorders of the pituitary gland and its
Disorders of the pituitary gland and its hypothalamic control
 Endocrine/metabolic 1.08 0.995 – 1.17 0.0668 681 6821 all phecode
253.1 Pituitary hyperfunction Endocrine/metabolic 1.07 0.923 – 1.25 0.353 187 1867 all phecode
253.11 Acromegaly and gigantism Endocrine/metabolic 1.03 0.839 – 1.26 0.786 95 949 all phecode
253.2 Pituitary hypofunction Endocrine/metabolic 1.07 0.941 – 1.21 0.312 260 2618 all phecode
253.3 Diabetes insipidus Endocrine/metabolic 0.959 0.778 – 1.18 0.697 92 919 all phecode
253.7 Other disorders of neurohypophysis Endocrine/metabolic 1.02 0.861 – 1.2 0.846 158 1578 all phecode
255 Disorders of adrenal glands Endocrine/metabolic 1.05 0.971 – 1.14 0.21 638 6374 all phecode
255.1 Adrenal hyperfunction Endocrine/metabolic 1.1 0.946 – 1.28 0.212 180 1797 all phecode
255.11 Cushing's syndrome Endocrine/metabolic 1 0.822 – 1.23 0.968 103 1029 all phecode
255.12 Hyperaldosteronism Endocrine/metabolic 1.27 1 – 1.61 0.0461 76 759 all phecode
255.2 Adrenal hypofunction Endocrine/metabolic 1.01 0.903 – 1.12 0.923 362 3617 all phecode
255.21 Glucocorticoid deficiency Endocrine/metabolic 1.01 0.904 – 1.12 0.906 361 3607 all phecode
256 Ovarian dysfunction Endocrine/metabolic 1.11 0.971 – 1.27 0.128 240 2397 all phecode
256.4 Polycystic ovaries Endocrine/metabolic 1.1 0.951 – 1.27 0.201 209 2088 all phecode
257 Testicular dysfunction Endocrine/metabolic 1.09 0.925 – 1.29 0.297 160 1619 all phecode
257.1 Testicular hypofunction Endocrine/metabolic 1.13 0.948 – 1.34 0.177 152 1539 all phecode
258 Iatrogenic endocrine disorders Endocrine/metabolic 1.07 0.875 – 1.3 0.524 102 1020 all phecode
259 Other endocrine disorders Endocrine/metabolic 1.04 0.873 – 1.23 0.688 149 1498 all phecode
260 Protein-calorie malnutrition Endocrine/metabolic 1.1 0.959 – 1.27 0.168 202 2018 all phecode
260.1 Cachexia Endocrine/metabolic 1.07 0.811 – 1.42 0.625 51 510 all phecode
260.6 Anorexia Endocrine/metabolic 1.01 0.939 – 1.08 0.818 830 8317 all phecode
261 Vitamin deficiency Endocrine/metabolic 1.07 1.01 – 1.13 0.0299 1199 11974 all phecode
261.2 Vitamin B-complex deficiencies Endocrine/metabolic 1.03 0.956 – 1.11 0.432 755 7541 all phecode
261.4 Vitamin D deficiency Endocrine/metabolic 1.13 1.03 – 1.25 0.0115 447 4462 all phecode
261.41 Rickets or osteomalacia Endocrine/metabolic 1.14 0.91 – 1.43 0.254 77 769 all phecode
262 Mineral deficiency NEC Endocrine/metabolic 0.919 0.806 – 1.05 0.212 241 2407 all phecode
269 Proteinuria Endocrine/metabolic 1.13 1.01 – 1.26 0.0352 338 3378 all phecode
270
Disorders of protein plasma/amino-acid
Disorders of protein plasma/amino-acid transport and metabolism
 Endocrine/metabolic 0.916 0.814 – 1.03 0.15 303 3028 all phecode
270.3 Disorders of plasma protein metabolism Endocrine/metabolic 0.913 0.803 – 1.04 0.166 261 2608 all phecode
270.32 Paraproteinemia Endocrine/metabolic 0.929 0.8 – 1.08 0.338 191 1910 all phecode
270.33 Amyloidosis Endocrine/metabolic 1.1 0.906 – 1.33 0.345 113 1129 all phecode
270.35 Macroglobulinemia Endocrine/metabolic 0.836 0.651 – 1.07 0.163 69 689 all phecode
271
Disorders of carbohydrate transport and
Disorders of carbohydrate transport and metabolism
 Endocrine/metabolic 1.28 1.08 – 1.51 0.00381 160 1600 all phecode
271.3
Intestinal disaccharidase deficiencies and
Intestinal disaccharidase deficiencies and disaccharide malabsorption
 Endocrine/metabolic 1.28 1.07 – 1.52 0.00726 139 1391 all phecode
272 Disorders of lipoid metabolism Endocrine/metabolic 1.11 1.09 – 1.12 3.54e-69 34835 235433 all phecode
272.1 Hyperlipidemia Endocrine/metabolic 1.11 1.1 – 1.12 8.71e-70 34764 235203 all phecode
272.11 Hypercholesterolemia Endocrine/metabolic 1.11 1.09 – 1.12 2.45e-64 32324 228083 all phecode
272.12 Hyperglyceridemia Endocrine/metabolic 1.3 1.01 – 1.67 0.0453 58 580 all phecode
272.13 Mixed hyperlipidemia Endocrine/metabolic 1.15 0.982 – 1.34 0.084 164 1637 all phecode
272.9 Unspecified disorder of lipoid metabolism Endocrine/metabolic 1.07 0.927 – 1.23 0.359 211 2109 all phecode
274 Gout and other crystal arthropathies Endocrine/metabolic 1.08 1.04 – 1.11 1.77e-05 3724 37231 all phecode
274.1 Gout Endocrine/metabolic 1.07 1.03 – 1.11 0.000148 3171 31705 all phecode
274.11 Gouty arthropathy Endocrine/metabolic 0.91 0.754 – 1.1 0.329 112 1119 all phecode
274.2 Crystal arthropathies Endocrine/metabolic 1.08 0.997 – 1.18 0.0574 613 6124 all phecode
274.21 Chondrocalcinosis Endocrine/metabolic 1.09 0.994 – 1.19 0.0664 558 5576 all phecode
275 Disorders of mineral metabolism Endocrine/metabolic 1.02 0.974 – 1.07 0.413 2107 21070 all phecode
275.1 Disorders of iron metabolism Hematopoietic 0.957 0.884 – 1.04 0.275 653 6535 all phecode
275.3 Disorders of magnesium metabolism Endocrine/metabolic 1.11 0.995 – 1.23 0.0624 375 3745 all phecode
275.5 Disorders of calcium/phosphorus metabolism Endocrine/metabolic 1.04 0.98 – 1.1 0.193 1202 12019 all phecode
275.53 Disorders of phosphorus metabolism Endocrine/metabolic 1.25 1.07 – 1.47 0.00467 171 1717 all phecode
276
Disorders of fluid, electrolyte, and acid-base
Disorders of fluid, electrolyte, and acid-base balance
 Endocrine/metabolic 1.06 1.04 – 1.09 1.16e-06 7284 72932 all phecode
276.1 Electrolyte imbalance Endocrine/metabolic 1.06 1.03 – 1.09 0.000418 4086 40930 all phecode
276.11 Hyperosmolality and/or hypernatremia Endocrine/metabolic 1.19 1.04 – 1.36 0.0116 239 2409 all phecode
276.12 Hyposmolality and/or hyponatremia Endocrine/metabolic 1.03 0.983 – 1.08 0.199 1818 18200 all phecode
276.13 Hyperpotassemia Endocrine/metabolic 1.13 1.06 – 1.21 0.000179 969 9728 all phecode
276.14 Hypopotassemia Endocrine/metabolic 1.01 0.952 – 1.06 0.833 1424 14235 all phecode
276.4 Acid-base balance disorder Endocrine/metabolic 1.1 1.04 – 1.17 0.00157 1161 11629 all phecode
276.41 Acidosis Endocrine/metabolic 1.09 1.03 – 1.17 0.00633 1056 10577 all phecode
276.42 Alkalosis Endocrine/metabolic 1.06 0.873 – 1.29 0.549 113 1129 all phecode
276.5 Hypovolemia Endocrine/metabolic 1.06 1.02 – 1.1 0.00309 2827 28265 all phecode
276.6 Fluid overload Endocrine/metabolic 1.03 0.939 – 1.14 0.502 451 4535 all phecode
276.8 Polydipsia Endocrine/metabolic 1.03 0.863 – 1.24 0.717 128 1278 all phecode
277 Other disorders of metabolism Endocrine/metabolic 1.02 0.948 – 1.09 0.663 899 8977 all phecode
277.4 Disorders of bilirubin excretion Endocrine/metabolic 0.965 0.866 – 1.07 0.509 362 3613 all phecode
277.5 Other disorders of lipoid metabolism Endocrine/metabolic 1.09 0.947 – 1.24 0.237 230 2298 all phecode
277.51 Lipoprotein disorders Endocrine/metabolic 0.865 0.661 – 1.13 0.292 52 520 all phecode
278 Overweight, obesity and other hyperalimentation Endocrine/metabolic 1.07 1.05 – 1.1 2.11e-12 10804 108289 all phecode
278.1 Obesity Endocrine/metabolic 1.07 1.05 – 1.09 4.87e-12 10642 106670 all phecode
278.3 Localized adiposity Endocrine/metabolic 1.12 0.9 – 1.4 0.304 84 838 all phecode
278.4 Abnormal weight gain Endocrine/metabolic 1.13 0.89 – 1.44 0.317 66 660 all phecode
279 Disorders involving the immune mechanism Endocrine/metabolic 1.02 0.902 – 1.16 0.709 250 2510 all phecode
279.1 Immunity deficiency Endocrine/metabolic 1 0.873 – 1.16 0.947 209 2100 all phecode
279.11 Deficiency of humoral immunity Endocrine/metabolic 0.86 0.724 – 1.02 0.0862 138 1390 all phecode
279.7 Other immunological findings Endocrine/metabolic 0.937 0.824 – 1.07 0.322 248 2478 all phecode
280 Iron deficiency anemias Hematopoietic 1.07 1.04 – 1.09 5.15e-08 7610 76168 all phecode
280.1
Iron deficiency anemias, unspecified or not due
Iron deficiency anemias, unspecified or not due to blood loss
 Hematopoietic 1.07 1.04 – 1.09 1.14e-07 7311 73153 all phecode
280.2
Iron deficiency anemia secondary to blood loss
Iron deficiency anemia secondary to blood loss (chronic)
 Hematopoietic 1.11 1 – 1.22 0.0413 452 4541 all phecode
281 Other deficiency anemia Hematopoietic 1.05 0.992 – 1.12 0.0872 1112 11126 all phecode
281.1 Megaloblastic anemia Hematopoietic 1.06 0.999 – 1.13 0.0542 1066 10669 all phecode
281.11 Pernicious anemia Hematopoietic 1.09 1.01 – 1.17 0.0257 750 7514 all phecode
281.12 Other vitamin B12 deficiency anemia Hematopoietic 1.27 1.09 – 1.48 0.00229 177 1769 all phecode
281.13 Folate-deficiency anemia Hematopoietic 0.836 0.717 – 0.975 0.0224 183 1836 all phecode
281.9 Deficiency anemias Hematopoietic 0.894 0.671 – 1.19 0.443 54 538 all phecode
282 Hereditary hemolytic anemias Hematopoietic 1.05 0.892 – 1.24 0.552 150 1499 all phecode
282.8 Other hemoglobinopathies Hematopoietic 1.13 0.86 – 1.48 0.384 56 560 all phecode
282.9 Other hereditary hemolytic anemias Hematopoietic 1.07 0.857 – 1.33 0.556 85 849 all phecode
283 Acquired hemolytic anemias Hematopoietic 1.03 0.862 – 1.22 0.77 135 1377 all phecode
283.1 Autoimmune hemolytic anemias Hematopoietic 0.964 0.791 – 1.17 0.717 103 1059 all phecode
284 Aplastic anemia Hematopoietic 0.998 0.905 – 1.1 0.975 435 4357 all phecode
285 Other anemias Hematopoietic 1.04 1.02 – 1.06 0.000212 12104 121094 all phecode
285.1 Acute posthemorrhagic anemia Hematopoietic 1.01 0.889 – 1.14 0.934 271 2707 all phecode
285.2 Anemia of chronic disease Hematopoietic 1.05 0.973 – 1.14 0.203 697 6980 all phecode
285.22 Anemia in neoplastic disease Hematopoietic 1.02 0.919 – 1.13 0.732 414 4147 all phecode
286 Coagulation defects Hematopoietic 1.02 0.952 – 1.09 0.599 921 9218 all phecode
286.1 Congenital coagulation defects Hematopoietic 1.01 0.914 – 1.11 0.9 459 4594 all phecode
286.11 Von willebrand's disease Hematopoietic 0.995 0.807 – 1.23 0.966 96 959 all phecode
286.12
Congenital deficiency of other clotting factors
Congenital deficiency of other clotting factors (including factor VII)
 Hematopoietic 1.01 0.896 – 1.14 0.85 294 2944 all phecode
286.13 Congenital factor VIII disorder Hematopoietic 1.22 0.945 – 1.56 0.128 63 630 all phecode
286.5
Hemorrhagic disorder due to intrinsic
Hemorrhagic disorder due to intrinsic circulating anticoagulants
 Hematopoietic 1.02 0.818 – 1.27 0.875 86 860 all phecode
286.7 Other and unspecified coagulation defects Hematopoietic 1.05 0.951 – 1.17 0.315 386 3867 all phecode
287 Purpura and other hemorrhagic conditions Hematopoietic 1.03 0.975 – 1.08 0.325 1652 16532 all phecode
287.1 Spontaneous ecchymoses Hematopoietic 0.964 0.807 – 1.15 0.685 129 1290 all phecode
287.2 Allergic purpura Hematopoietic 1.14 0.846 – 1.54 0.383 51 510 all phecode
287.3 Thrombocytopenia Hematopoietic 1.01 0.959 – 1.07 0.67 1553 15543 all phecode
287.31 Primary thrombocytopenia Hematopoietic 1.02 0.922 – 1.13 0.689 419 4195 all phecode
287.32 Secondary thrombocytopenia Hematopoietic 0.965 0.761 – 1.22 0.771 75 749 all phecode
288 Diseases of white blood cells Hematopoietic 1.02 0.984 – 1.05 0.317 3765 37672 all phecode
288.1 Decreased white blood cell count Hematopoietic 1.02 0.982 – 1.06 0.323 3168 31704 all phecode
288.11 Neutropenia Hematopoietic 1.02 0.982 – 1.06 0.328 3176 31784 all phecode
288.3 Eosinophilia Hematopoietic 0.957 0.758 – 1.21 0.71 71 709 all phecode
289 Other diseases of blood and blood-forming organs Hematopoietic 1 0.933 – 1.07 0.985 862 8625 all phecode
289.3
Personal history of diseases of blood and
Personal history of diseases of blood and blood-forming organs
 Hematopoietic 1.04 0.921 – 1.17 0.545 290 2897 all phecode
289.4 Lymphadenitis Hematopoietic 0.989 0.95 – 1.03 0.604 2602 26061 all phecode
289.5 Diseases of spleen Hematopoietic 1.05 0.964 – 1.15 0.247 516 5153 all phecode
289.8 Polycythemia, secondary Hematopoietic 1.01 0.895 – 1.14 0.891 292 2917 all phecode
289.9 Abnormality of red blood cells Hematopoietic 0.952 0.77 – 1.18 0.647 90 900 all phecode
290
Delirium dementia and amnestic and other
Delirium dementia and amnestic and other cognitive disorders
 Mental Disorders 1.01 0.96 – 1.05 0.804 1929 19281 all phecode
290.1 Dementias Mental Disorders 0.98 0.919 – 1.05 0.534 1004 10032 all phecode
290.11 Alzheimer's disease Mental Disorders 1.01 0.914 – 1.11 0.868 431 4307 all phecode
290.16 Vascular dementia Mental Disorders 0.997 0.862 – 1.15 0.968 201 2008 all phecode
290.2 Delirium due to conditions classified elsewhere Mental Disorders 1.05 0.969 – 1.14 0.236 650 6501 all phecode
290.3
Other persistent mental disorders due to
Other persistent mental disorders due to conditions classified elsewhere
 Mental Disorders 0.995 0.783 – 1.26 0.967 70 709 all phecode
291
Other specified nonpsychotic and/or transient
Other specified nonpsychotic and/or transient mental disorders
 Mental Disorders 1.02 0.952 – 1.1 0.535 836 8385 all phecode
291.1
Transient mental disorders due to conditions
Transient mental disorders due to conditions classified elsewhere
 Mental Disorders 1.06 0.892 – 1.27 0.49 132 1320 all phecode
291.4
Specific nonpsychotic mental disorders due to
Specific nonpsychotic mental disorders due to brain damage
 Mental Disorders 0.957 0.846 – 1.08 0.477 286 2867 all phecode
291.8 Alteration of consciousness Mental Disorders 1.07 0.972 – 1.18 0.167 436 4376 all phecode
292 Neurological disorders Mental Disorders 1.04 1.01 – 1.08 0.00467 4621 46260 all phecode
292.1 Aphasia/speech disturbance Mental Disorders 1.06 1 – 1.12 0.0371 1504 15074 all phecode
292.2 Mild cognitive impairment Mental Disorders 0.99 0.854 – 1.15 0.893 190 1907 all phecode
292.3 Memory loss Mental Disorders 1.08 1 – 1.17 0.0414 696 6978 all phecode
292.4 Altered mental status Mental Disorders 1.06 1.01 – 1.1 0.015 2181 21827 all phecode
292.6 Hallucinations Mental Disorders 0.977 0.868 – 1.1 0.703 307 3073 all phecode
293 Symptoms involving head and neck Mental Disorders 0.971 0.929 – 1.02 0.207 2078 20779 all phecode
293.1
Swelling, mass, or lump in head and neck
Swelling, mass, or lump in head and neck [Space-occupying lesion, intracranial NOS]
 Mental Disorders 1.02 0.952 – 1.09 0.595 901 9010 all phecode
295 Schizophrenia and other psychotic disorders Mental Disorders 0.954 0.888 – 1.02 0.192 841 8446 all phecode
295.1 Schizophrenia Mental Disorders 0.935 0.857 – 1.02 0.129 574 5766 all phecode
295.2 Paranoid disorders Mental Disorders 0.998 0.854 – 1.17 0.981 178 1780 all phecode
295.3 Psychosis Mental Disorders 0.886 0.76 – 1.03 0.119 169 1710 all phecode
296 Mood disorders Mental Disorders 1.03 1.01 – 1.05 0.00113 12372 123822 all phecode
296.1 Bipolar Mental Disorders 0.974 0.915 – 1.04 0.413 1059 10599 all phecode
296.2 Depression Mental Disorders 1.03 1.02 – 1.05 0.000454 11737 117469 all phecode
296.22 Major depressive disorder Mental Disorders 0.971 0.874 – 1.08 0.591 361 3604 all phecode
297.2 Suicide or self-inflicted injury Mental Disorders 1.09 0.976 – 1.23 0.122 311 3070 all phecode
300 Anxiety disorders Mental Disorders 1.02 0.996 – 1.05 0.101 6844 68484 all phecode
300.1 Anxiety disorder Mental Disorders 1.02 0.994 – 1.05 0.126 6324 63282 all phecode
300.11 Generalized anxiety disorder Mental Disorders 0.958 0.81 – 1.13 0.614 149 1499 all phecode
300.12 Agorophobia, social phobia, and panic disorder Mental Disorders 1.02 0.941 – 1.1 0.671 707 7065 all phecode
300.13 Phobia Mental Disorders 1.02 0.927 – 1.11 0.731 501 5013 all phecode
300.3 Obsessive-compulsive disorders Mental Disorders 1.13 0.954 – 1.34 0.157 140 1407 all phecode
300.4 Dysthymic disorder Mental Disorders 1.13 0.858 – 1.5 0.376 53 530 all phecode
300.8 Acute reaction to stress Mental Disorders 1.1 0.918 – 1.32 0.303 124 1238 all phecode
300.9 Posttraumatic stress disorder Mental Disorders 0.894 0.738 – 1.08 0.252 113 1129 all phecode
301 Personality disorders Mental Disorders 1.08 0.968 – 1.21 0.169 334 3338 all phecode
301.2 Antisocial/borderline personality disorder Mental Disorders 1.05 0.88 – 1.26 0.569 119 1186 all phecode
302 Sexual and gender identity disorders Mental Disorders 1.14 1.01 – 1.29 0.0395 283 2845 all phecode
303 Psychogenic and somatoform disorders Mental Disorders 1.03 0.938 – 1.13 0.524 467 4679 all phecode
303.3 Psychogenic disorder Mental Disorders 1.03 0.919 – 1.14 0.657 350 3510 all phecode
303.4 Somatoform disorder Mental Disorders 1.11 0.922 – 1.33 0.279 123 1229 all phecode
304 Adjustment reaction Mental Disorders 1.01 0.899 – 1.14 0.82 293 2936 all phecode
305.2 Eating disorder Mental Disorders 1.02 0.826 – 1.26 0.847 90 900 all phecode
306 Other mental disorder Mental Disorders 1.06 1.04 – 1.07 1.46e-18 28056 230087 all phecode
306.9 Tension headache Mental Disorders 1.02 0.909 – 1.14 0.734 315 3148 all phecode
313 Pervasive developmental disorders Mental Disorders 0.857 0.685 – 1.07 0.177 76 770 all phecode
313.3 Autism Mental Disorders 0.851 0.655 – 1.11 0.229 53 539 all phecode
315 Develomental delays and disorders Mental Disorders 1.13 1.01 – 1.26 0.0317 351 3517 all phecode
315.1 Learning disorder Mental Disorders 1.09 0.929 – 1.28 0.287 161 1610 all phecode
315.2 Speech and language disorder Mental Disorders 1.18 0.943 – 1.49 0.146 88 880 all phecode
316 Substance addiction and disorders Mental Disorders 1.03 1 – 1.06 0.0244 5313 53131 all phecode
316.1 Polyneuropathy due to drugs Mental Disorders 1.23 0.963 – 1.58 0.0975 60 599 all phecode
317 Alcohol-related disorders Mental Disorders 1.03 1.01 – 1.05 0.00346 12696 126892 all phecode
317.1 Alcoholism Mental Disorders 1.03 1.01 – 1.06 0.00242 8890 88923 all phecode
317.11 Alcoholic liver damage Mental Disorders 1.1 1.03 – 1.18 0.00722 838 8392 all phecode
318 Tobacco use disorder Mental Disorders 1.05 1.04 – 1.07 2.53e-12 19359 185465 all phecode
320 Meningitis Neurological 1.03 0.932 – 1.13 0.591 444 4447 all phecode
323 Encephalitis Neurological 0.967 0.867 – 1.08 0.551 342 3422 all phecode
323.2 Acute (transverse) myelitis Neurological 0.921 0.725 – 1.17 0.5 74 739 all phecode
324 Other CNS infection and poliomyelitis Neurological 1.04 0.92 – 1.18 0.526 292 2916 all phecode
327 Sleep disorders Neurological 1.03 0.974 – 1.1 0.274 1164 11659 all phecode
327.3 Sleep apnea Neurological 1.09 1.06 – 1.12 5.38e-08 4428 44318 all phecode
327.4 Insomnia Neurological 1.02 0.872 – 1.2 0.773 163 1660 all phecode
327.41 Organic or persistent insomnia Neurological 0.992 0.831 – 1.18 0.93 136 1390 all phecode
331 Other cerebral degenerations Neurological 1.01 0.953 – 1.08 0.687 1142 11416 all phecode
331.1 Hydrocephalus Neurological 0.998 0.913 – 1.09 0.959 502 5014 all phecode
331.9 Cerebral degeneration, unspecified Neurological 1.07 0.97 – 1.18 0.175 430 4298 all phecode
332 Parkinson's disease Neurological 0.951 0.895 – 1.01 0.11 1126 11254 all phecode
333
Extrapyramidal disease and abnormal movement
Extrapyramidal disease and abnormal movement disorders
 Neurological 0.99 0.924 – 1.06 0.768 894 8954 all phecode
333.1 Essential tremor Neurological 0.95 0.827 – 1.09 0.474 216 2157 all phecode
333.2 Myoclonus Neurological 1.27 1.03 – 1.57 0.0252 96 958 all phecode
333.4 Torsion dystonia Neurological 0.978 0.864 – 1.11 0.728 253 2528 all phecode
334 Degenerative disease of the spinal cord Neurological 1.07 1.02 – 1.12 0.00623 1812 18130 all phecode
334.1 Spinocerebellar disease Neurological 1.09 0.899 – 1.32 0.38 117 1169 all phecode
334.2 Anterior horn cell disease Neurological 1.06 0.934 – 1.21 0.351 245 2446 all phecode
335 Multiple sclerosis Neurological 0.919 0.868 – 0.972 0.0032 1340 13385 all phecode
337 Disorders of the autonomic nervous system Neurological 1.04 0.921 – 1.18 0.497 266 2668 all phecode
337.1 Peripheral autonomic neuropathy Neurological 0.926 0.727 – 1.18 0.53 72 719 all phecode
338 Pain Neurological 1.07 0.998 – 1.16 0.0563 768 7692 all phecode
338.1 Acute pain Neurological 1.09 0.979 – 1.2 0.118 394 3937 all phecode
338.2 Chronic pain Neurological 1.08 0.977 – 1.2 0.126 380 3817 all phecode
339 Other headache syndromes Neurological 1.06 1.03 – 1.08 3.48e-06 7819 78241 all phecode
340 Migraine Neurological 0.986 0.949 – 1.02 0.478 2860 28602 all phecode
340.1 Migrain with aura Neurological 0.879 0.766 – 1.01 0.0673 212 2117 all phecode
341
Other demyelinating diseases of central nervous
Other demyelinating diseases of central nervous system
 Neurological 1.16 1.02 – 1.33 0.0243 252 2535 all phecode
342 Hemiplegia Neurological 1.05 0.996 – 1.11 0.0691 1494 14947 all phecode
343 Infantile cerebral palsy Neurological 1.11 0.942 – 1.3 0.216 145 1450 all phecode
344 Other paralytic syndromes Neurological 1.09 1.01 – 1.18 0.0331 658 6593 all phecode
345 Epilepsy, recurrent seizures, convulsions Neurological 1.03 1 – 1.06 0.0234 5023 50270 all phecode
345.1 Epilepsy Neurological 1.03 0.959 – 1.1 0.446 866 8661 all phecode
345.11 Generalized convulsive epilepsy Neurological 1.06 0.963 – 1.17 0.231 439 4385 all phecode
345.12 Partial epilepsy Neurological 1.01 0.893 – 1.14 0.888 277 2776 all phecode
345.3 Convulsions Neurological 1 0.96 – 1.05 0.92 2235 22339 all phecode
346.1
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of skull and head
 Neurological 1.04 0.88 – 1.23 0.645 144 1438 all phecode
348 Other conditions of brain Neurological 1.06 0.982 – 1.14 0.142 778 7808 all phecode
348.2 Cerebral edema and compression of brain Neurological 1.07 0.946 – 1.21 0.281 268 2678 all phecode
348.4 Cerebral cysts Neurological 0.866 0.724 – 1.04 0.115 133 1350 all phecode
348.7 Coma Neurological 1.11 1 – 1.24 0.0477 358 3596 all phecode
348.8 Encephalopathy, not elsewhere classified Neurological 1.19 1.05 – 1.36 0.00868 249 2504 all phecode
348.9 Other conditions of brain, NOS Neurological 0.926 0.836 – 1.03 0.144 390 3899 all phecode
349
Other and unspecified disorders of the nervous
Other and unspecified disorders of the nervous system
 Neurological 1.02 0.913 – 1.14 0.742 342 3414 all phecode
350 Abnormal movement Neurological 1.05 1.01 – 1.09 0.0201 2671 26722 all phecode
350.1 Abnormal involuntary movements Neurological 1.1 1.03 – 1.18 0.00754 887 8852 all phecode
350.2 Abnormality of gait Neurological 1.01 0.963 – 1.07 0.612 1596 15969 all phecode
350.3 Lack of coordination Neurological 1.1 0.986 – 1.22 0.088 363 3638 all phecode
350.6 Disturbances of sensation of smell and taste Neurological 1.23 0.927 – 1.62 0.154 54 540 all phecode
351 Other peripheral nerve disorders Neurological 1.04 1.02 – 1.06 4.16e-05 12420 124321 all phecode
352 Disorders of other cranial nerves Neurological 1.01 0.954 – 1.07 0.753 1370 13706 all phecode
352.1 Trigeminal nerve disorders [CN5] Neurological 0.963 0.875 – 1.06 0.438 463 4638 all phecode
352.2 Facial nerve disorders [CN7] Neurological 1.02 0.955 – 1.1 0.508 880 8795 all phecode
353 Nerve root and plexus disorders Neurological 1.06 0.995 – 1.12 0.0728 1131 11319 all phecode
353.1 Nerve plexus lesions Neurological 0.979 0.809 – 1.18 0.826 114 1138 all phecode
353.2 Nerve root lesions Neurological 1.17 0.885 – 1.55 0.27 57 570 all phecode
356 Hereditary and idiopathic peripheral neuropathy Neurological 0.801 0.676 – 0.948 0.0101 152 1520 all phecode
357 Inflammatory and toxic neuropathy Neurological 1.12 1.06 – 1.19 6.28e-05 1361 13648 all phecode
358 Myoneural disorders Neurological 0.937 0.813 – 1.08 0.365 211 2109 all phecode
358.1 Myasthenia gravis Neurological 0.934 0.805 – 1.08 0.373 192 1919 all phecode
359 Muscular dystrophies and other myopathies Neurological 1.13 1.02 – 1.24 0.014 465 4646 all phecode
359.1 Muscular dystrophies Neurological 1.19 0.988 – 1.44 0.0661 122 1219 all phecode
359.2 Myopathy Neurological 1.1 0.99 – 1.23 0.0759 360 3597 all phecode
360 Disorders of the globe Sense Organs 1.07 0.957 – 1.2 0.228 337 3367 all phecode
360.2 Progressive myopia Sense Organs 1.08 0.946 – 1.23 0.259 251 2508 all phecode
361 Retinal detachments and defects Sense Organs 0.992 0.957 – 1.03 0.675 3246 32453 all phecode
361.1 Retinal detachment with retinal defect Sense Organs 0.999 0.945 – 1.06 0.966 1389 13884 all phecode
361.2 Retinoschisis and retinal cysts Sense Organs 0.961 0.752 – 1.23 0.749 68 680 all phecode
362 Other retinal disorders Sense Organs 1.04 1 – 1.07 0.028 3836 38370 all phecode
362.2
Degeneration of macula and posterior pole of
Degeneration of macula and posterior pole of retina
 Sense Organs 1.01 0.965 – 1.05 0.703 2182 21813 all phecode
362.29 Macular degeneration (senile) of retina NOS Sense Organs 1.01 0.965 – 1.05 0.716 2179 21783 all phecode
362.3 Other nondiabetic retinopathy Sense Organs 1.17 0.985 – 1.38 0.0741 161 1609 all phecode
362.31 Separation of retinal layers Sense Organs 1.09 0.885 – 1.35 0.407 99 990 all phecode
362.4 Retinal vascular changes and abnomalities Sense Organs 1.09 1.01 – 1.16 0.0212 848 8477 all phecode
362.6 Peripheral retinal degenerations Sense Organs 0.976 0.839 – 1.14 0.758 182 1827 all phecode
362.7 Hereditary retinal dystrophies Sense Organs 1.1 0.889 – 1.37 0.368 82 812 all phecode
362.8 Retinal hemorrhage/ischemia Sense Organs 0.939 0.775 – 1.14 0.52 116 1159 all phecode
363
Chorioretinal inflammations, scars, and other
Chorioretinal inflammations, scars, and other disorders of choroid
 Sense Organs 0.854 0.731 – 0.997 0.0456 170 1699 all phecode
363.3 Chorioretinal scars Sense Organs 0.831 0.649 – 1.06 0.14 69 690 all phecode
364 Corneal opacity and other disorders of cornea Sense Organs 1 0.926 – 1.09 0.941 647 6485 all phecode
364.1 Corneal opacity Sense Organs 0.962 0.78 – 1.19 0.716 90 910 all phecode
364.2 Corneal edema Sense Organs 1.05 0.835 – 1.32 0.683 79 800 all phecode
364.4 Corneal degenerations Sense Organs 1.05 0.904 – 1.21 0.545 201 2017 all phecode
364.41 Keratoconus Sense Organs 0.871 0.702 – 1.08 0.212 86 869 all phecode
364.5 Corneal dystrophy Sense Organs 0.932 0.81 – 1.07 0.324 211 2109 all phecode
364.9 Cornea replaced by transplant Sense Organs 1.05 0.859 – 1.29 0.622 100 1000 all phecode
365 Glaucoma Sense Organs 1.04 1.01 – 1.07 0.0176 4408 44136 all phecode
365.1 Open-angle glaucoma Sense Organs 1.09 1.02 – 1.16 0.00973 1032 10346 all phecode
365.11 Primary open angle glaucoma Sense Organs 1.08 1.01 – 1.15 0.0159 1026 10287 all phecode
365.2 Primary angle-closure glaucoma Sense Organs 0.977 0.904 – 1.06 0.548 698 6996 all phecode
366 Cataract Sense Organs 1.03 1.01 – 1.04 0.000144 19926 168711 all phecode
366.1 Nonsenile Cataract Sense Organs 1.18 0.934 – 1.49 0.165 69 700 all phecode
366.2 Senile cataract Sense Organs 1.04 1.01 – 1.06 0.00131 8231 81909 all phecode
366.3 Traumatic cataract Sense Organs 1.12 0.905 – 1.38 0.304 102 1019 all phecode
367
Disorders of refraction and accommodation
Disorders of refraction and accommodation; blindness and low vision
 Sense Organs 1.03 0.988 – 1.07 0.162 2408 24092 all phecode
367.1 Myopia Sense Organs 1.03 0.972 – 1.09 0.305 1251 12519 all phecode
367.2 Astigmatism Sense Organs 0.983 0.847 – 1.14 0.824 190 1899 all phecode
367.8 Hypermetropia Sense Organs 0.943 0.829 – 1.07 0.377 253 2530 all phecode
367.9 Blindness and low vision Sense Organs 1.08 1 – 1.17 0.0423 719 7198 all phecode
368 Visual disturbances Sense Organs 1.03 0.989 – 1.07 0.158 2962 29648 all phecode
368.1 Amblyopia Sense Organs 0.925 0.845 – 1.01 0.0904 532 5322 all phecode
368.2 Diplopia and disorders of binocular vision Sense Organs 1.03 0.951 – 1.11 0.499 727 7288 all phecode
368.3 Anisometropia Sense Organs 1.2 1.02 – 1.41 0.0299 154 1548 all phecode
368.4 Visual field defects Sense Organs 0.976 0.872 – 1.09 0.672 333 3327 all phecode
368.9 Subjective visual disturbances Sense Organs 1.07 0.981 – 1.16 0.132 612 6115 all phecode
369 Infection of the eye Sense Organs 1.03 0.948 – 1.13 0.448 553 5544 all phecode
369.2 Eye infection, viral Sense Organs 0.953 0.795 – 1.14 0.606 125 1257 all phecode
369.5 Conjunctivitis, infectious Sense Organs 1.05 0.909 – 1.21 0.525 213 2128 all phecode
370 Keratitis Sense Organs 1 0.891 – 1.13 0.94 286 2855 all phecode
370.1 Corneal ulcer Sense Organs 0.986 0.834 – 1.17 0.872 141 1408 all phecode
371 Inflammation of the eye Sense Organs 0.98 0.944 – 1.02 0.292 3045 30480 all phecode
371.1 Uveitis, noninfectious or NOS Sense Organs 0.958 0.871 – 1.05 0.371 482 4821 all phecode
371.3 Inflammation of eyelids Sense Organs 0.989 0.948 – 1.03 0.607 2353 23555 all phecode
372 Disorders of conjunctiva Sense Organs 0.939 0.871 – 1.01 0.1 760 7602 all phecode
374 Other disorders of eyelids Sense Organs 1.02 0.992 – 1.05 0.169 5680 56807 all phecode
374.1 Ectropion or entropion Sense Organs 1.01 0.949 – 1.08 0.742 1063 10645 all phecode
374.3 Ptosis of eyelid Sense Organs 1.07 1.02 – 1.12 0.00902 1825 18232 all phecode
375 Disorders of lacrimal system Sense Organs 1.04 0.994 – 1.08 0.0897 2204 22031 all phecode
375.2 Epiphora Sense Organs 0.999 0.932 – 1.07 0.966 898 8969 all phecode
376 Disorders of the orbit Sense Organs 0.935 0.75 – 1.17 0.549 86 859 all phecode
377 Disorders of optic nerve and visual pathways Sense Organs 1.09 0.978 – 1.22 0.119 361 3618 all phecode
377.1 Optic atrophy Sense Organs 0.937 0.708 – 1.24 0.647 56 570 all phecode
377.3 Optic neuritis/neuropathy Sense Organs 1.17 0.973 – 1.4 0.0958 125 1249 all phecode
378
Strabismus and other disorders of binocular eye
Strabismus and other disorders of binocular eye movements
 Sense Organs 1.01 0.958 – 1.07 0.672 1410 14116 all phecode
378.1 Strabismus (not specified as paralytic) Sense Organs 0.982 0.918 – 1.05 0.605 909 9082 all phecode
378.2 Nystagmus and other irregular eye movements Sense Organs 1.16 1.01 – 1.34 0.0365 213 2138 all phecode
378.5 Paralytic strabismus Sense Organs 1.02 0.902 – 1.16 0.732 275 2755 all phecode
379 Other disorders of eye Sense Organs 1.03 0.996 – 1.07 0.0834 3703 37063 all phecode
379.2 Disorders of vitreous body Sense Organs 1.04 0.986 – 1.1 0.146 1367 13665 all phecode
379.3 Aphakia and other disorders of lens Sense Organs 1.04 0.99 – 1.09 0.124 1813 18134 all phecode
379.4 Anomalies of pupillary function Sense Organs 1.4 1.1 – 1.8 0.00739 71 710 all phecode
379.5 Disorders of iris and ciliary body Sense Organs 1.01 0.915 – 1.12 0.804 400 4028 all phecode
379.9 Pain, swelling or discharge of eye Sense Organs 1.09 0.936 – 1.28 0.258 169 1690 all phecode
380 Disorders of external ear Sense Organs 1 0.923 – 1.08 0.999 642 6413 all phecode
380.1 Otitis externa Sense Organs 1.06 0.967 – 1.16 0.224 509 5107 all phecode
380.4 Impacted cerumen Sense Organs 1.14 1.03 – 1.27 0.0134 362 3614 all phecode
381 Otitis media and Eustachian tube disorders Sense Organs 1.05 1.01 – 1.1 0.0266 2150 21493 all phecode
381.1 Otitis media Sense Organs 1.07 1.02 – 1.12 0.0104 1767 17668 all phecode
381.11 Suppurative and unspecified otitis media Sense Organs 1.07 1 – 1.15 0.0407 852 8524 all phecode
381.2 Eustachian tube disorders Sense Organs 0.962 0.831 – 1.11 0.599 193 1929 all phecode
381.3 Mastoiditis & related conditions Sense Organs 1.2 1.02 – 1.41 0.025 171 1709 all phecode
381.9 Otorrhea Sense Organs 1.03 0.914 – 1.16 0.611 281 2807 all phecode
382 Otalgia Sense Organs 0.982 0.874 – 1.1 0.753 308 3084 all phecode
383 Otosclerosis Sense Organs 0.907 0.808 – 1.02 0.0999 309 3090 all phecode
384 Other disorders of tympanic membrane Sense Organs 1.1 1.04 – 1.17 0.000897 1299 12991 all phecode
384.4 Perforation of tympanic membrane Sense Organs 1.14 1.07 – 1.22 5.23e-05 1043 10432 all phecode
385 Other disorders of middle ear and mastoid Sense Organs 1.08 1.01 – 1.17 0.0297 783 7837 all phecode
385.3 Cholesteatoma Sense Organs 1.06 0.981 – 1.16 0.135 607 6078 all phecode
385.5
Tympanosclerosis and middle ear disease related
Tympanosclerosis and middle ear disease related to otitis media
 Sense Organs 1.08 0.946 – 1.23 0.257 241 2409 all phecode
386
Vertiginous syndromes and other disorders of
Vertiginous syndromes and other disorders of vestibular system
 Sense Organs 1.02 0.972 – 1.07 0.416 1736 17373 all phecode
386.1 Meniere's disease Sense Organs 0.979 0.898 – 1.07 0.625 576 5768 all phecode
386.2 Peripheral or central vertigo Sense Organs 0.98 0.881 – 1.09 0.704 377 3763 all phecode
386.3 Labyrinthitis Sense Organs 1.06 0.986 – 1.14 0.115 765 7664 all phecode
386.9
Dizziness and giddiness (Light-headedness and
Dizziness and giddiness (Light-headedness and vertigo)
 Sense Organs 1.05 1.02 – 1.08 0.0033 4582 45806 all phecode
388 Other disorders of ear Sense Organs 1.07 0.927 – 1.23 0.365 202 2017 all phecode
389 Hearing loss Sense Organs 1.05 1.01 – 1.08 0.00437 4188 41944 all phecode
389.1 Sensorineural hearing loss Sense Organs 0.986 0.896 – 1.09 0.781 456 4553 all phecode
389.2 Conductive hearing loss Sense Organs 1.08 0.978 – 1.19 0.131 450 4497 all phecode
389.4 Tinnitus Sense Organs 1.07 0.973 – 1.17 0.17 513 5134 all phecode
394 Rheumatic disease of the heart valves Circulatory System 1.02 0.992 – 1.05 0.159 4899 48974 all phecode
394.2 Mitral valve disease Circulatory System 1.02 0.984 – 1.06 0.268 2993 29922 all phecode
394.3 Aortic valve disease Circulatory System 0.996 0.94 – 1.05 0.883 1282 12814 all phecode
394.7 Disease of tricuspid valve Circulatory System 1.04 0.981 – 1.11 0.174 1058 10566 all phecode
395 Heart valve disorders Circulatory System 1.02 0.988 – 1.05 0.216 4223 42219 all phecode
395.1 Nonrheumatic mitral valve disorders Circulatory System 1.02 0.98 – 1.06 0.349 2891 28900 all phecode
395.2 Nonrheumatic aortic valve disorders Circulatory System 1.02 0.902 – 1.15 0.753 276 2766 all phecode
395.3 Nonrheumatic tricuspid valve disorders Circulatory System 0.878 0.718 – 1.07 0.203 105 1039 all phecode
395.4 Nonrheumatic pulmonary valve disorders Circulatory System 0.944 0.769 – 1.16 0.581 97 970 all phecode
395.6 Heart valve replaced Circulatory System 1.02 0.971 – 1.08 0.397 1495 14942 all phecode
396 Abnormal heart sounds Circulatory System 1.04 0.976 – 1.11 0.23 1048 10468 all phecode
401 Hypertension Circulatory System 1.11 1.1 – 1.12 1.74e-127 73956 266957 all phecode
401.1 Essential hypertension Circulatory System 1.11 1.1 – 1.12 2.22e-126 73731 266739 all phecode
401.2 Hypertensive heart and/or renal disease Circulatory System 1.17 1.12 – 1.23 5.73e-11 1898 19031 all phecode
401.21 Hypertensive heart disease Circulatory System 1.13 1.02 – 1.26 0.0254 370 3699 all phecode
401.22 Hypertensive chronic kidney disease Circulatory System 1.17 1.11 – 1.24 2.97e-09 1543 15483 all phecode
401.3 Other hypertensive complications Circulatory System 1.22 1.03 – 1.45 0.0215 144 1438 all phecode
402
Elevated blood pressure reading without
Elevated blood pressure reading without diagnosis of hypertension
 Circulatory System 1.12 1.06 – 1.18 2.11e-05 1479 14786 all phecode
411 Ischemic Heart Disease Circulatory System 1.09 1.08 – 1.1 9.7e-46 31245 210714 all phecode
411.1 Unstable angina (intermediate coronary syndrome) Circulatory System 1.11 1.07 – 1.14 6.76e-12 5152 51498 all phecode
411.2 Myocardial infarction Circulatory System 1.1 1.08 – 1.12 7.94e-24 11950 112699 all phecode
411.3 Angina pectoris Circulatory System 1.1 1.08 – 1.12 1.12e-30 15888 143745 all phecode
411.4 Coronary atherosclerosis Circulatory System 1.1 1.08 – 1.12 7.25e-36 20171 154621 all phecode
411.41 Aneurysm and dissection of heart Circulatory System 1.06 0.982 – 1.15 0.135 700 6997 all phecode
411.8
Other chronic ischemic heart disease
Other chronic ischemic heart disease, unspecified
 Circulatory System 1.1 1.09 – 1.12 7.98e-31 15290 131798 all phecode
411.9
Other acute and subacute forms of ischemic
Other acute and subacute forms of ischemic heart disease
 Circulatory System 1.07 1.01 – 1.13 0.0256 1218 12166 all phecode
414 Other forms of chronic heart disease Circulatory System 1.11 1.06 – 1.17 1.68e-05 1823 18228 all phecode
414.2 ASCVD Circulatory System 1 0.786 – 1.28 0.976 72 719 all phecode
415 Pulmonary heart disease Circulatory System 0.993 0.963 – 1.02 0.648 4476 44810 all phecode
415.11 Pulmonary embolism and infarction, acute Circulatory System 0.952 0.759 – 1.19 0.671 75 750 all phecode
415.2 Chronic pulmonary heart disease Circulatory System 1.02 0.938 – 1.11 0.643 601 6002 all phecode
415.21 Primary pulmonary hypertension Circulatory System 1.02 0.927 – 1.12 0.679 448 4475 all phecode
416 Cardiomegaly Circulatory System 1.05 1.01 – 1.1 0.00976 2680 26793 all phecode
418 Nonspecific chest pain Circulatory System 1.06 1.05 – 1.07 2.42e-21 28599 270106 all phecode
418.1 Precordial pain Circulatory System 1.05 1.01 – 1.08 0.00817 3551 35541 all phecode
420 Carditis Circulatory System 0.994 0.95 – 1.04 0.786 2106 21053 all phecode
420.1 Myocarditis Circulatory System 1.07 0.89 – 1.29 0.471 127 1267 all phecode
420.2 Pericarditis Circulatory System 0.981 0.927 – 1.04 0.511 1338 13371 all phecode
420.21 Acute pericarditis Circulatory System 0.973 0.849 – 1.12 0.699 223 2227 all phecode
420.22 Chronic pericarditis Circulatory System 1.16 0.954 – 1.4 0.138 113 1129 all phecode
420.3 Endocarditis Circulatory System 1.01 0.94 – 1.09 0.722 719 7194 all phecode
425 Cardiomyopathy Circulatory System 1.07 1.01 – 1.13 0.0299 1271 12699 all phecode
425.1 Primary/intrinsic cardiomyopathies Circulatory System 1.07 1.01 – 1.14 0.0171 1236 12349 all phecode
425.11 Hypertrophic obstructive cardiomyopathy Circulatory System 0.944 0.788 – 1.13 0.526 133 1329 all phecode
425.12 Other hypertrophic cardiomyopathy Circulatory System 0.915 0.777 – 1.08 0.289 163 1629 all phecode
425.8 Other cardiomyopathy Circulatory System 0.836 0.641 – 1.09 0.188 60 600 all phecode
426 Cardiac conduction disorders Circulatory System 1.06 1.04 – 1.09 1.72e-06 6910 69146 all phecode
426.2 Atrioventricular [AV] block Circulatory System 1.09 1.05 – 1.14 7.95e-05 2114 21162 all phecode
426.21 First degree AV block Circulatory System 1.13 1.06 – 1.2 0.000307 986 9867 all phecode
426.23 Second degree AV block Circulatory System 1.11 1 – 1.22 0.0426 452 4515 all phecode
426.24 Atrioventricular block, complete Circulatory System 1.12 1.03 – 1.22 0.00693 587 5868 all phecode
426.25 Other heart block Circulatory System 0.934 0.782 – 1.12 0.452 131 1318 all phecode
426.3 Bundle branch block Circulatory System 1.06 1.03 – 1.1 0.000561 3336 33359 all phecode
426.31 Right bundle branch block Circulatory System 1.03 0.975 – 1.08 0.302 1494 14933 all phecode
426.32 Left bundle branch block Circulatory System 1.1 1.05 – 1.16 0.000151 1750 17503 all phecode
426.4 Anomalous atrioventricular excitation Circulatory System 1.06 0.929 – 1.22 0.374 233 2328 all phecode
426.8 Other cardiac conduction disorders Circulatory System 1.03 0.79 – 1.35 0.818 60 600 all phecode
426.9 Cardiac pacemaker/device in situ Circulatory System 1.06 1.01 – 1.1 0.0107 2475 24774 all phecode
426.91 Cardiac pacemaker in situ Circulatory System 1.06 1.01 – 1.1 0.0137 2274 22762 all phecode
427 Cardiac dysrhythmias Circulatory System 1.03 1.01 – 1.04 0.000134 24207 206016 all phecode
427.1 Paroxysmal tachycardia, unspecified Circulatory System 1.04 1 – 1.08 0.0532 3199 32017 all phecode
427.11 Paroxysmal supraventricular tachycardia Circulatory System 1.03 0.99 – 1.08 0.134 2344 23474 all phecode
427.12 Paroxysmal ventricular tachycardia Circulatory System 1.07 1 – 1.15 0.0423 936 9365 all phecode
427.2 Atrial fibrillation and flutter Circulatory System 1.03 1.01 – 1.05 0.00167 14628 133501 all phecode
427.3 Other specified cardiac dysrhythmias Circulatory System 1.05 1.01 – 1.09 0.00892 3228 32281 all phecode
427.4 Cardiac arrest and ventricular fibrillation Circulatory System 1.04 0.981 – 1.11 0.182 1193 11915 all phecode
427.41 Ventricular fibrillation and flutter Circulatory System 1.05 0.936 – 1.17 0.419 344 3437 all phecode
427.42 Cardiac arrest Circulatory System 1.03 0.968 – 1.1 0.328 990 9890 all phecode
427.5 Arrhythmia (cardiac) NOS Circulatory System 1 0.934 – 1.07 0.991 952 9541 all phecode
427.6 Premature beats Circulatory System 1.01 0.926 – 1.11 0.796 535 5358 all phecode
427.61 Supraventricular premature beats Circulatory System 1.09 0.9 – 1.31 0.387 117 1168 all phecode
427.7 Tachycardia NOS Circulatory System 1 0.961 – 1.05 0.859 2185 21865 all phecode
427.8 Sinoatrial node dysfunction (Bradycardia) Circulatory System 1.01 0.909 – 1.12 0.87 402 4029 all phecode
427.9 Palpitations Circulatory System 1 0.97 – 1.04 0.89 3811 38105 all phecode
428 Congestive heart failure; nonhypertensive Circulatory System 1.09 1.06 – 1.12 1e-09 5605 56018 all phecode
428.1 Congestive heart failure (CHF) NOS Circulatory System 1.09 1.04 – 1.14 0.00014 2111 21108 all phecode
428.2 Heart failure NOS Circulatory System 1.09 1.05 – 1.12 9.08e-08 4455 44524 all phecode
429
Ill-defined descriptions and complications of
Ill-defined descriptions and complications of heart disease
 Circulatory System 1.07 0.994 – 1.16 0.0719 716 7168 all phecode
429.1 Heart transplant/surgery Circulatory System 1.08 0.849 – 1.38 0.526 64 639 all phecode
429.2 Abnormal function study of cardiovascular system Circulatory System 1.03 0.941 – 1.13 0.526 522 5211 all phecode
429.3 Symptoms involving cardiovascular system Circulatory System 1.21 1.04 – 1.4 0.0112 196 1978 all phecode
430 Intracranial hemorrhage Circulatory System 1.03 0.988 – 1.08 0.151 1883 18825 all phecode
430.1 Subarachnoid hemorrhage Circulatory System 1.05 0.982 – 1.13 0.149 836 8353 all phecode
430.2 Intracerebral hemorrhage Circulatory System 0.99 0.92 – 1.07 0.799 765 7656 all phecode
430.3 Subdural hemorrhage Circulatory System 1.03 0.908 – 1.17 0.649 267 2667 all phecode
433 Cerebrovascular disease Circulatory System 1.06 1.03 – 1.08 9.47e-07 8749 87456 all phecode
433.1 Occlusion and stenosis of precerebral arteries Circulatory System 1.1 1.04 – 1.17 0.00163 1185 11825 all phecode
433.12 Cerebral atherosclerosis Circulatory System 1.16 1.01 – 1.33 0.0318 227 2267 all phecode
433.2 Occlusion of cerebral arteries Circulatory System 1.07 1.04 – 1.1 3.76e-05 4233 42320 all phecode
433.21
Cerebral artery occlusion, with cerebral
Cerebral artery occlusion, with cerebral infarction
 Circulatory System 1.13 1.08 – 1.19 1.57e-06 1680 16794 all phecode
433.3 Cerebral ischemia Circulatory System 1.03 0.996 – 1.08 0.079 2895 28989 all phecode
433.31 Transient cerebral ischemia Circulatory System 1.04 0.997 – 1.09 0.0645 2135 21379 all phecode
433.5 Cerebral aneurysm Circulatory System 1.06 0.955 – 1.17 0.276 394 3939 all phecode
433.8 Late effects of cerebrovascular disease Circulatory System 1.05 0.991 – 1.11 0.101 1279 12783 all phecode
440 Atherosclerosis Circulatory System 1.2 1.14 – 1.27 6.57e-11 1380 13822 all phecode
440.1 Atherosclerosis of renal artery Circulatory System 1.23 1.02 – 1.48 0.0283 113 1129 all phecode
440.2 Atherosclerosis of the extremities Circulatory System 1.21 1.13 – 1.3 1.88e-07 805 8070 all phecode
440.9 Atherosclerosis of aorta Circulatory System 1.16 1.03 – 1.32 0.0141 287 2867 all phecode
441 Vascular insufficiency of intestine Circulatory System 1.09 1 – 1.18 0.0502 614 6154 all phecode
441.1 Acute vascular insufficiency of intestine Circulatory System 1.05 0.932 – 1.19 0.398 283 2827 all phecode
442 Other aneurysm Circulatory System 0.992 0.945 – 1.04 0.731 1892 18959 all phecode
442.1 Aortic aneurysm Circulatory System 0.985 0.933 – 1.04 0.578 1458 14625 all phecode
442.11 Abdominal aortic aneurysm Circulatory System 1 0.935 – 1.07 0.982 931 9341 all phecode
442.2 Aneurysm of iliac artery Circulatory System 0.908 0.743 – 1.11 0.345 102 1019 all phecode
442.3 Aneurysm of artery of lower extremity Circulatory System 1.1 0.942 – 1.29 0.226 169 1696 all phecode
442.4 Arterial dissection Circulatory System 0.984 0.742 – 1.3 0.909 54 549 all phecode
442.8 Aneurysm of other specified artery Circulatory System 0.936 0.809 – 1.08 0.377 203 2028 all phecode
443 Peripheral vascular disease Circulatory System 1.11 1.07 – 1.15 4.62e-10 3921 39273 all phecode
443.1 Raynaud's syndrome Circulatory System 0.998 0.939 – 1.06 0.941 1145 11438 all phecode
443.7
Peripheral angiopathy in diseases classified
Peripheral angiopathy in diseases classified elsewhere
 Circulatory System 1.51 1.36 – 1.68 3.15e-14 384 3878 all phecode
443.8 Other specified peripheral vascular diseases Circulatory System 1.09 1.05 – 1.13 4.49e-07 3686 36906 all phecode
443.9 Peripheral vascular disease, unspecified Circulatory System 1.15 1.1 – 1.2 1.29e-11 2579 25846 all phecode
444 Arterial embolism and thrombosis Circulatory System 1.09 1.02 – 1.16 0.0123 922 9251 all phecode
444.1
Arterial embolism and thrombosis of lower
Arterial embolism and thrombosis of lower extremity artery
 Circulatory System 1.2 1.1 – 1.31 4.01e-05 554 5552 all phecode
446 Polyarteritis nodosa and allied conditions Circulatory System 1.07 0.998 – 1.15 0.0582 822 8226 all phecode
446.4 Wegener's granulomatosis Circulatory System 1.01 0.87 – 1.18 0.865 188 1878 all phecode
446.5 Giant cell arteritis Circulatory System 1.08 0.973 – 1.2 0.147 388 3879 all phecode
446.9 Arteritis NOS Circulatory System 1.06 0.929 – 1.21 0.388 239 2400 all phecode
447 Other disorders of arteries and arterioles Circulatory System 1.12 1.06 – 1.19 3.72e-05 1327 13316 all phecode
447.1 Stricture of artery Circulatory System 1.2 1.12 – 1.29 2.49e-07 868 8712 all phecode
448 Disease of capillaries Circulatory System 0.93 0.787 – 1.1 0.393 142 1420 all phecode
450 Noninfectious disorders of lymphatic channels Circulatory System 0.993 0.919 – 1.07 0.856 704 7034 all phecode
451 Phlebitis and thrombophlebitis Circulatory System 1.01 0.977 – 1.04 0.574 3955 39683 all phecode
451.2
Phlebitis and thrombophlebitis of lower
Phlebitis and thrombophlebitis of lower extremities
 Circulatory System 1.01 0.976 – 1.04 0.574 3683 36977 all phecode
452 Other venous embolism and thrombosis Circulatory System 1.05 0.964 – 1.14 0.262 564 5645 all phecode
454 Varicose veins Circulatory System 0.986 0.967 – 1 0.141 11180 112047 all phecode
454.1 Varicose veins of lower extremity Circulatory System 0.98 0.961 – 0.999 0.0347 11503 115272 all phecode
454.11 Varicose veins of lower extremity, symptomtic Circulatory System 0.957 0.88 – 1.04 0.305 624 6325 all phecode
455 Hemorrhoids Circulatory System 1 0.99 – 1.02 0.641 23452 234585 all phecode
456 Chronic venous insufficiency [CVI] Circulatory System 0.832 0.714 – 0.969 0.018 184 1868 all phecode
457
Encounter for long-term (current) use of
Encounter for long-term (current) use of anticoagulants, antithrombotics, aspirin
 Circulatory System 0.935 0.761 – 1.15 0.519 97 967 all phecode
458 Hypotension Circulatory System 1.02 0.99 – 1.04 0.231 5769 57772 all phecode
458.1 Orthostatic hypotension Circulatory System 1.07 1.02 – 1.13 0.0124 1335 13376 all phecode
458.2 Iatrogenic hypotension Circulatory System 1.04 0.911 – 1.19 0.552 235 2348 all phecode
458.9 Hypotension NOS Circulatory System 1.01 0.972 – 1.04 0.702 3494 35005 all phecode
459 Other disorders of circulatory system Circulatory System 1.03 1.02 – 1.05 4.47e-05 16268 160790 all phecode
459.1 Hemorrhage NOS Circulatory System 1.08 0.909 – 1.28 0.385 142 1420 all phecode
459.9 Circulatory disease NEC Circulatory System 1.04 1.02 – 1.05 2.6e-05 16103 159422 all phecode
464 Acute sinusitis Respiratory 1.21 1.05 – 1.4 0.0102 196 1957 all phecode
465
Acute upper respiratory infections of multiple
Acute upper respiratory infections of multiple or unspecified sites
 Respiratory 1.02 0.98 – 1.07 0.303 2283 22827 all phecode
465.2 Acute pharyngitis Respiratory 1.01 0.937 – 1.08 0.856 835 8348 all phecode
465.4 Acute laryngitis and tracheitis Respiratory 0.956 0.818 – 1.12 0.577 165 1649 all phecode
470 Septal Deviations/Turbinate Hypertrophy Respiratory 1.02 0.993 – 1.05 0.142 4654 46553 all phecode
471 Nasal polyps Respiratory 1.05 1.01 – 1.09 0.00791 3297 32973 all phecode
472 Chronic pharyngitis and nasopharyngitis Respiratory 1.01 0.944 – 1.08 0.799 960 9594 all phecode
473 Diseases of the larynx and vocal cords Respiratory 0.993 0.954 – 1.03 0.75 2554 25548 all phecode
473.1 Chronic laryngitis Respiratory 0.932 0.772 – 1.13 0.467 104 1038 all phecode
473.3 Paralysis/spasm of vocal cords or larynx Respiratory 1.02 0.9 – 1.16 0.733 264 2647 all phecode
473.4 Voice disturbance Respiratory 0.968 0.909 – 1.03 0.314 1080 10789 all phecode
474 Acute and chronic tonsillitis Respiratory 1.04 0.991 – 1.09 0.112 1772 17710 all phecode
474.1 Acute tonsillitis Respiratory 1.1 1.01 – 1.2 0.0367 549 5486 all phecode
474.2 Chronic tonsillitis and adenoiditis Respiratory 1.04 0.977 – 1.1 0.229 1122 11199 all phecode
475 Chronic sinusitis Respiratory 1.04 1 – 1.08 0.0454 2589 25882 all phecode
476 Allergic rhinitis Respiratory 1.01 0.948 – 1.08 0.749 1055 10563 all phecode
477 Epistaxis or throat hemorrhage Respiratory 1.03 0.989 – 1.07 0.151 2447 24452 all phecode
478 Throat pain Respiratory 0.995 0.896 – 1.11 0.93 377 3789 all phecode
479 Other upper respiratory disease Respiratory 1.03 0.993 – 1.06 0.124 4074 40737 all phecode
480 Pneumonia Respiratory 1.02 0.995 – 1.04 0.143 10336 103397 all phecode
480.1 Bacterial pneumonia Respiratory 1 0.976 – 1.03 0.964 6637 66410 all phecode
480.11 Pneumococcal pneumonia Respiratory 0.993 0.967 – 1.02 0.624 5883 58863 all phecode
480.12 Pseudomonal pneumonia Respiratory 1.23 0.993 – 1.51 0.0582 93 929 all phecode
480.2 Viral pneumonia Respiratory 1.06 0.835 – 1.35 0.63 72 720 all phecode
480.3 Pneumonia due to fungus (mycoses) Respiratory 0.918 0.748 – 1.13 0.415 99 989 all phecode
480.5 Bronchopneumonia and lung abscess Respiratory 1.06 0.985 – 1.14 0.122 794 7951 all phecode
481 Influenza Respiratory 1.1 0.985 – 1.23 0.0901 328 3278 all phecode
483 Acute bronchitis and bronchiolitis Respiratory 1.18 1.02 – 1.37 0.0234 193 1930 all phecode
495 Asthma Respiratory 1.06 1.04 – 1.07 9.31e-17 25689 250406 all phecode
495.2 Asthma with exacerbation Respiratory 1.11 0.976 – 1.27 0.11 250 2510 all phecode
496 Chronic airway obstruction Respiratory 1.06 1.04 – 1.09 2.09e-09 10424 101546 all phecode
496.1 Emphysema Respiratory 1.09 1.04 – 1.14 0.000757 1743 17438 all phecode
496.2 Chronic bronchitis Respiratory 1.08 1.04 – 1.12 0.000186 2947 29498 all phecode
496.21 Obstructive chronic bronchitis Respiratory 1.08 1.04 – 1.12 0.000173 2706 27081 all phecode
496.3 Bronchiectasis Respiratory 1 0.955 – 1.05 0.955 1885 18859 all phecode
497 Bronchitis Respiratory 0.923 0.851 – 1 0.0551 626 6267 all phecode
500 Lung disease due to external agents Respiratory 1.03 0.935 – 1.14 0.518 412 4099 all phecode
500.1 Extrinsic allergic alveolitis Respiratory 1.01 0.806 – 1.26 0.954 79 784 all phecode
500.2 Pneumoconiosis Respiratory 1.08 0.952 – 1.23 0.223 243 2409 all phecode
501 Pneumonitis due to inhalation of food or vomitus Respiratory 1.05 0.971 – 1.14 0.21 656 6557 all phecode
502 Postinflammatory pulmonary fibrosis Respiratory 1.04 0.971 – 1.11 0.271 917 9193 all phecode
503 Pulmonary congestion and hypostasis Respiratory 1.17 1.06 – 1.28 0.000955 508 5079 all phecode
504 Other alveolar and parietoalveolar pneumonopathy Respiratory 1.06 0.942 – 1.18 0.351 328 3280 all phecode
505 Other pulmonary inflamation or edema Respiratory 1.13 0.877 – 1.46 0.34 61 610 all phecode
506 Empyema and pneumothorax Respiratory 1.03 0.968 – 1.09 0.361 1133 11362 all phecode
507 Pleurisy; pleural effusion Respiratory 1.02 0.994 – 1.05 0.137 6419 64252 all phecode
508
Pulmonary collapse; interstitial and
Pulmonary collapse; interstitial and compensatory emphysema
 Respiratory 1.01 0.969 – 1.06 0.551 1996 19947 all phecode
509 Respiratory failure, insufficiency, arrest Respiratory 1.07 1.02 – 1.11 0.00198 2599 26031 all phecode
509.1 Respiratory failure Respiratory 1.07 1.02 – 1.12 0.00396 2068 20708 all phecode
509.2 Respiratory insufficiency Respiratory 1.06 1.01 – 1.12 0.0153 1806 18106 all phecode
509.5 Respiratory arrest Respiratory 1.04 0.881 – 1.24 0.622 143 1429 all phecode
509.8
Dependence on respirator [Ventilator] or
Dependence on respirator [Ventilator] or supplemental oxygen
 Respiratory 1.13 1.01 – 1.25 0.0253 386 3863 all phecode
510 Other diseases of lung Respiratory 1.04 0.968 – 1.13 0.267 755 7554 all phecode
512 Other symptoms of respiratory system Respiratory 1.03 1.01 – 1.06 0.00352 9031 90349 all phecode
512.1 Wheezing Respiratory 1 0.873 – 1.16 0.952 220 2196 all phecode
512.2 Painful respiration Respiratory 1.06 0.917 – 1.22 0.443 207 2075 all phecode
512.7 Shortness of breath Respiratory 1.04 1.01 – 1.07 0.00746 5842 58498 all phecode
512.8 Cough Respiratory 1.02 0.977 – 1.05 0.447 2866 28642 all phecode
512.9 Other dyspnea Respiratory 1.04 0.967 – 1.11 0.314 914 9124 all phecode
513 Respiratory abnormalities Respiratory 1.04 0.96 – 1.13 0.319 611 6112 all phecode
513.3 Hypoventilation Respiratory 0.964 0.775 – 1.2 0.74 83 830 all phecode
513.4 Hyperventilation Respiratory 1.1 0.975 – 1.24 0.124 278 2778 all phecode
513.8 Disorders of diaphragm Respiratory 1.05 0.888 – 1.24 0.584 153 1538 all phecode
514 Abnormal findings examination of lungs Respiratory 1.02 0.975 – 1.06 0.455 2465 24673 all phecode
516 Abnormal sputum Respiratory 1.03 0.985 – 1.08 0.199 2132 21335 all phecode
516.1 Hemoptysis Respiratory 1.03 0.98 – 1.07 0.271 2073 20745 all phecode
519
Other diseases of respiratory system, not
Other diseases of respiratory system, not elsewhere classified
 Respiratory 1.05 1.02 – 1.07 3.1e-05 9366 93681 all phecode
519.2 Respiratory complications Respiratory 1.06 0.947 – 1.19 0.314 327 3279 all phecode
519.8 Other diseases of respiratory system, NEC Respiratory 1.05 1.02 – 1.07 7.62e-05 8853 88522 all phecode
519.9
Symptoms involving respiratory system and other
Symptoms involving respiratory system and other chest symptoms
 Respiratory 0.977 0.869 – 1.1 0.696 303 3049 all phecode
520 Disorders of tooth development Digestive 0.991 0.946 – 1.04 0.686 2038 20354 all phecode
520.1 Hereditary disturbances in tooth structure Digestive 0.942 0.716 – 1.24 0.667 53 530 all phecode
520.2 Disturbances in tooth eruption Digestive 0.999 0.957 – 1.04 0.958 2356 23539 all phecode
521 Diseases of hard tissues of teeth Digestive 1.03 0.994 – 1.07 0.097 3016 30245 all phecode
521.1 Dental caries Digestive 1.04 0.998 – 1.08 0.0643 3026 30353 all phecode
522 Diseases of pulp and periapical tissues Digestive 0.989 0.941 – 1.04 0.651 1774 17750 all phecode
522.5 Periapical abscess Digestive 1.01 0.947 – 1.07 0.839 1172 11731 all phecode
523 Gingival and periodontal diseases Digestive 1.03 0.982 – 1.09 0.206 1681 16812 all phecode
523.1 Gingivitis Digestive 1.06 0.875 – 1.27 0.572 113 1127 all phecode
523.3 Periodontitis (acute or chronic) Digestive 1.03 0.972 – 1.1 0.305 1165 11650 all phecode
523.31 Acute periodontitis Digestive 1.05 0.968 – 1.14 0.242 666 6667 all phecode
523.32 Chronic periodontitis Digestive 1.02 0.931 – 1.11 0.721 560 5594 all phecode
524 Dentofacial anomalies, including malocclusion Digestive 0.995 0.889 – 1.11 0.934 331 3307 all phecode
524.3 Anomalies of tooth position/malocclusion Digestive 1.02 0.911 – 1.15 0.693 305 3046 all phecode
525
Other diseases of the teeth and supporting
Other diseases of the teeth and supporting structures
 Digestive 1 0.963 – 1.04 0.943 2668 26728 all phecode
525.2 Atrophy of edentulous alveolar ridge Digestive 0.917 0.735 – 1.14 0.442 72 720 all phecode
526 Diseases of the jaws Digestive 1.02 0.952 – 1.09 0.589 928 9279 all phecode
526.1 Cysts of the jaws Digestive 1.01 0.899 – 1.13 0.899 329 3289 all phecode
526.3 Anomalies of jaw size/symmetry Digestive 1.11 0.86 – 1.44 0.414 61 610 all phecode
526.4 Temporomandibular joint disorders Digestive 1.02 0.894 – 1.16 0.793 240 2406 all phecode
526.41 Temporomandibular joint disorder, unspecified Digestive 1.03 0.903 – 1.18 0.646 233 2336 all phecode
526.5 Inflammatory conditions of jaw Digestive 0.955 0.788 – 1.16 0.642 110 1098 all phecode
526.9 Jaw disease NOS Digestive 0.987 0.862 – 1.13 0.852 233 2329 all phecode
527 Diseases of the salivary glands Digestive 1.04 0.964 – 1.13 0.297 694 6943 all phecode
527.1 Hypertrophy of salivary gland Digestive 1.14 0.91 – 1.44 0.252 84 838 all phecode
527.2 Sialoadenitis Digestive 1.05 0.941 – 1.17 0.383 365 3656 all phecode
527.7 Disturbance of salivary secretion Digestive 0.811 0.631 – 1.04 0.101 62 619 all phecode
527.8 Other specified diseases of the salivary glands Digestive 1.01 0.839 – 1.22 0.899 120 1200 all phecode
528
Diseases of the oral soft tissues, excluding
Diseases of the oral soft tissues, excluding lesions specific for gingiva and tongue
 Digestive 1.03 0.997 – 1.07 0.0711 3873 38741 all phecode
528.1 Stomatitis and mucositis Digestive 1.05 0.956 – 1.16 0.301 468 4675 all phecode
528.11 Stomatitis and mucositis (ulcerative) Digestive 1.08 0.977 – 1.2 0.131 389 3884 all phecode
528.12 Oral aphthae Digestive 0.974 0.779 – 1.22 0.82 84 840 all phecode
528.3 Cellulitis and abscess of oral soft tissues Digestive 0.984 0.847 – 1.14 0.828 179 1790 all phecode
528.4 Cysts of oral soft tissues Digestive 1.11 0.928 – 1.34 0.247 122 1219 all phecode
528.41 Cyst of the salivary gland Digestive 1.12 0.908 – 1.38 0.292 94 940 all phecode
528.5 Diseases of lips Digestive 1.02 0.946 – 1.11 0.575 681 6813 all phecode
528.6 Leukoplakia of oral mucosa Digestive 1.03 0.92 – 1.16 0.593 308 3079 all phecode
528.7 Sialolithiasis Digestive 1 0.89 – 1.13 0.983 314 3138 all phecode
529 Diseases and other conditions of the tongue Digestive 1.04 0.978 – 1.1 0.231 1232 12312 all phecode
529.1 Glossitis Digestive 1.14 1.01 – 1.28 0.031 299 2986 all phecode
530 Diseases of esophagus Digestive 1.04 1.03 – 1.05 9.51e-11 33453 279172 all phecode
530.1 Esophagitis, GERD and related diseases Digestive 1.04 1.03 – 1.06 1.66e-12 31253 272429 all phecode
530.11 GERD Digestive 1.04 1.03 – 1.06 2.17e-09 22633 225879 all phecode
530.12 Ulcer of esophagus Digestive 1.05 1.02 – 1.08 0.000309 5203 52068 all phecode
530.14 Reflux esophagitis Digestive 1.05 1.03 – 1.07 7.74e-06 10444 104493 all phecode
530.2 Esophageal bleeding (varices/hemorrhage) Digestive 0.998 0.949 – 1.05 0.929 1681 16808 all phecode
530.3 Stricture and stenosis of esophagus Digestive 1 0.955 – 1.05 0.931 1869 18684 all phecode
530.5 Disorders of esophageal motility Digestive 0.989 0.912 – 1.07 0.79 635 6365 all phecode
530.6 Diverticulum of esophagus, acquired Digestive 1.01 0.856 – 1.19 0.923 153 1527 all phecode
530.7 Gastroesophageal laceration-hemorrhage syndrome Digestive 1.02 0.91 – 1.14 0.756 341 3416 all phecode
530.9 Heartburn Digestive 1.01 0.967 – 1.06 0.634 2087 20881 all phecode
531 Peptic ulcer (excl. esophageal) Digestive 1.05 1.03 – 1.08 3.53e-05 7103 71066 all phecode
531.1 Hemorrhage from gastrointestinal ulcer Digestive 1.05 0.97 – 1.14 0.221 637 6374 all phecode
531.2 Gastric ulcer Digestive 1.03 1 – 1.07 0.0415 4091 40941 all phecode
531.3 Duodenal ulcer Digestive 1.09 1.05 – 1.13 1.44e-05 2999 30005 all phecode
531.4 Peptic ulcer, site unspecified Digestive 1.04 0.943 – 1.15 0.415 427 4268 all phecode
532 Dysphagia Digestive 1.02 0.991 – 1.04 0.202 6427 64329 all phecode
535 Gastritis and duodenitis Digestive 1.03 1.02 – 1.05 1.36e-07 28078 261548 all phecode
535.1 Acute gastritis Digestive 1.1 1.04 – 1.17 0.0018 1183 11833 all phecode
535.2 Atrophic gastritis Digestive 1.01 0.906 – 1.12 0.893 370 3687 all phecode
535.6 Duodenitis Digestive 1.04 1.02 – 1.07 0.000252 7592 75928 all phecode
535.8 Other specified gastritis Digestive 1.04 1.02 – 1.07 0.000494 8071 80763 all phecode
535.9 Gastritis and duodenitis, NOS Digestive 1.28 1.06 – 1.55 0.0117 120 1191 all phecode
536.8
Dyspepsia and other specified disorders of
Dyspepsia and other specified disorders of function of stomach
 Digestive 1.09 0.961 – 1.24 0.179 259 2576 all phecode
537 Other disorders of stomach and duodenum Digestive 1.03 0.996 – 1.07 0.0787 3391 33907 all phecode
540 Appendiceal conditions Digestive 1.02 0.982 – 1.06 0.316 3088 30890 all phecode
540.1 Appendicitis Digestive 1.01 0.976 – 1.05 0.48 2895 28963 all phecode
540.11 Acute appendicitis Digestive 1 0.961 – 1.04 0.96 2601 26019 all phecode
550 Abdominal hernia Digestive 1.02 1.01 – 1.03 0.000214 45429 282640 all phecode
550.1 Inguinal hernia Digestive 0.983 0.967 – 1 0.0492 15794 123247 all phecode
550.2 Diaphragmatic hernia Digestive 1.03 1.02 – 1.05 1.99e-07 26494 238953 all phecode
550.3 Femoral hernia Digestive 0.966 0.892 – 1.05 0.406 651 6504 all phecode
550.4 Umbilical hernia Digestive 1.02 0.984 – 1.05 0.3 3705 37072 all phecode
550.5 Ventral hernia Digestive 1.04 1 – 1.07 0.0472 3435 34338 all phecode
555
Inflammatory bowel disease and other
Inflammatory bowel disease and other gastroenteritis and colitis
 Digestive 1.03 1 – 1.06 0.0465 4444 44442 all phecode
555.1 Regional enteritis Digestive 1.08 1.03 – 1.14 0.00136 1734 17340 all phecode
555.2 Ulcerative colitis Digestive 1.01 0.972 – 1.05 0.674 3178 31786 all phecode
555.21 Ulcerative colitis (chronic) Digestive 1.01 0.921 – 1.1 0.91 538 5382 all phecode
556 Ulceration of the lower GI tract Digestive 1.05 0.986 – 1.12 0.128 1055 10592 all phecode
556.1 Ulceration of intestine Digestive 1.05 0.968 – 1.13 0.25 670 6714 all phecode
557 Intestinal malabsorption (non-celiac) Digestive 1.02 0.906 – 1.15 0.741 299 2987 all phecode
557.1 Celiac disease Digestive 1.07 1.02 – 1.12 0.00783 1837 18388 all phecode
558 Noninfectious gastroenteritis Digestive 1.05 1.03 – 1.06 9.62e-08 15492 155105 all phecode
559 Ileostomy status Digestive 1.04 0.988 – 1.09 0.138 1656 16541 all phecode
560 Intestinal obstruction without mention of hernia Digestive 1.02 0.984 – 1.05 0.312 3936 39337 all phecode
560.1 Paralytic ileus Digestive 1.03 0.941 – 1.12 0.53 523 5231 all phecode
560.2 Impaction of intestine Digestive 0.96 0.848 – 1.09 0.528 268 2671 all phecode
560.3 Peritoneal or intestinal adhesions Digestive 1.03 0.956 – 1.1 0.468 832 8317 all phecode
560.4 Other intestinal obstruction Digestive 1.02 0.981 – 1.05 0.359 3358 33550 all phecode
561 Symptoms involving digestive system Digestive 1.02 1 – 1.04 0.011 15772 157686 all phecode
561.1 Diarrhea Digestive 0.943 0.857 – 1.04 0.229 466 4653 all phecode
561.2 Flatulence Digestive 1.01 0.958 – 1.06 0.781 1687 16859 all phecode
562 Diverticulosis and diverticulitis Digestive 1.04 1.02 – 1.05 2.43e-08 26714 211692 all phecode
562.1 Diverticulosis Digestive 1.04 1.02 – 1.05 2.41e-08 26672 211642 all phecode
563 Constipation Digestive 1.02 1 – 1.04 0.0274 10314 103140 all phecode
564 Functional digestive disorders Digestive 1.04 1.03 – 1.06 3.35e-08 21639 209949 all phecode
564.1 Irritable Bowel Syndrome Digestive 1.05 1.02 – 1.08 0.00127 5508 55117 all phecode
564.8
Abnormal findings on exam of gastrointestinal
Abnormal findings on exam of gastrointestinal tract/ abdominal area
 Digestive 1.04 0.993 – 1.1 0.0952 1645 16457 all phecode
564.9 Personal history of diseases of digestive system Digestive 1.04 1.03 – 1.06 3.4e-07 15186 151648 all phecode
565 Anal and rectal conditions Digestive 1.03 1.01 – 1.05 0.00151 14744 147535 all phecode
565.1 Anal and rectal polyp Digestive 1.03 1 – 1.05 0.0194 7351 73533 all phecode
567 Peritonitis and retroperitoneal infections Digestive 1.03 0.966 – 1.1 0.35 929 9293 all phecode
568 Other disorders of peritoneum Digestive 1.03 0.996 – 1.07 0.0827 3262 32602 all phecode
568.1
Peritoneal adhesions (postoperative)
Peritoneal adhesions (postoperative) (postinfection)
 Digestive 1.04 1 – 1.08 0.0522 3101 30987 all phecode
569 Other disorders of intestine Digestive 1.05 1.02 – 1.08 0.00209 4192 41922 all phecode
569.1 Toxic gastroenteritis and colitis Digestive 1.1 0.934 – 1.31 0.247 148 1479 all phecode
569.2 Gastrointestinal complications Digestive 1.01 0.917 – 1.1 0.906 486 4868 all phecode
571 Chronic liver disease and cirrhosis Digestive 1.12 1.08 – 1.16 4.23e-09 2957 29628 all phecode
571.5 Other chronic nonalcoholic liver disease Digestive 1.18 1.12 – 1.24 8.72e-11 1689 16917 all phecode
571.51 Cirrhosis of liver without mention of alcohol Digestive 1.29 1.06 – 1.56 0.00946 113 1139 all phecode
571.6 Primary biliary cirrhosis Digestive 0.988 0.871 – 1.12 0.855 257 2568 all phecode
571.8
Liver abscess and sequelae of chronic liver
Liver abscess and sequelae of chronic liver disease
 Digestive 1.05 0.98 – 1.12 0.171 976 9804 all phecode
571.81 Portal hypertension Digestive 1.08 0.987 – 1.18 0.0932 528 5285 all phecode
572 Ascites (non malignant) Digestive 1.08 1.03 – 1.14 0.0039 1544 15454 all phecode
573 Other disorders of liver Digestive 0.97 0.92 – 1.02 0.266 1496 14982 all phecode
573.2 Liver replaced by transplant Digestive 1.12 0.913 – 1.36 0.286 96 960 all phecode
573.3 Hepatomegaly Digestive 1.09 0.967 – 1.22 0.16 297 2968 all phecode
573.5 Jaundice (not of newborn) Digestive 1.05 0.983 – 1.13 0.143 896 8955 all phecode
573.7 Abnormal results of function study of liver Digestive 1.08 1.04 – 1.12 2.74e-05 3454 34597 all phecode
573.9 Abnormal serum enzyme levels Digestive 1.01 0.875 – 1.17 0.896 209 2089 all phecode
574 Cholelithiasis and cholecystitis Digestive 1.08 1.06 – 1.09 3.71e-18 15607 156123 all phecode
574.1 Cholelithiasis Digestive 1.07 1.05 – 1.09 3.24e-15 13549 135537 all phecode
574.11 Cholelithiasis with acute cholecystitis Digestive 1.12 1.06 – 1.18 3.68e-05 1506 15072 all phecode
574.12 Cholelithiasis with other cholecystitis Digestive 1.06 1.03 – 1.09 2.52e-05 5429 54289 all phecode
574.2 Calculus of bile duct Digestive 1.05 1.01 – 1.09 0.0138 2620 26191 all phecode
574.3 Cholecystitis without cholelithiasis Digestive 1.12 1.08 – 1.16 2.34e-08 2748 27523 all phecode
575 Other biliary tract disease Digestive 1.05 1.01 – 1.08 0.00675 3867 38724 all phecode
575.1 Cholangitis Digestive 1.07 0.975 – 1.17 0.152 495 4945 all phecode
575.2 Obstruction of bile duct Digestive 0.978 0.908 – 1.05 0.548 774 7756 all phecode
575.6 Cholesterolosis of gallbladder Digestive 1.15 1.04 – 1.26 0.0046 458 4577 all phecode
575.7 Other disorders of gallbladder Digestive 1.05 0.998 – 1.11 0.0579 1408 14107 all phecode
575.8 Other disorders of biliary tract Digestive 1.02 0.961 – 1.09 0.453 1036 10367 all phecode
575.9
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of biliary tract
 Digestive 0.987 0.886 – 1.1 0.819 348 3488 all phecode
577 Diseases of pancreas Digestive 1.1 1.06 – 1.15 2.2e-06 2668 26677 all phecode
577.1 Acute pancreatitis Digestive 1.12 1.07 – 1.18 8.61e-07 1996 19962 all phecode
577.2 Chronic pancreatitis Digestive 1.11 1.02 – 1.22 0.0203 515 5149 all phecode
577.3 Cyst and pseudocyst of pancreas Digestive 1.16 1.04 – 1.29 0.00845 365 3650 all phecode
578 Gastrointestinal hemorrhage Digestive 1.02 1 – 1.03 0.0326 20626 206278 all phecode
578.1 Hematemesis Digestive 1.05 1 – 1.1 0.0456 1958 19564 all phecode
578.2 Blood in stool Digestive 1.03 0.994 – 1.08 0.0991 2626 26283 all phecode
578.8 Hemorrhage of rectum and anus Digestive 1.01 0.996 – 1.03 0.117 13073 130745 all phecode
578.9 Hemorrhage of gastrointestinal tract Digestive 0.998 0.97 – 1.03 0.874 5275 52787 all phecode
579 Other symptoms involving abdomen and pelvis Digestive 0.995 0.944 – 1.05 0.856 1548 15498 all phecode
579.2 Splenomegaly Digestive 1.02 0.924 – 1.13 0.683 422 4246 all phecode
579.8 Nonspecific abnormal findings in stool contents Digestive 1 0.954 – 1.06 0.9 1654 16540 all phecode
580 Nephritis; nephrosis; renal sclerosis Genitourinary 1.1 1.05 – 1.16 0.000236 1531 15350 all phecode
580.1 Glomerulonephritis Genitourinary 1.09 1.03 – 1.17 0.0053 1052 10544 all phecode
580.11 Proliferative glomerulonephritis Genitourinary 0.939 0.742 – 1.19 0.6 74 738 all phecode
580.12 Non-proliferative glomerulonephritis Genitourinary 1.02 0.851 – 1.22 0.848 135 1360 all phecode
580.14 Chronic glomerulonephritis, NOS Genitourinary 1.1 1.03 – 1.18 0.0071 876 8769 all phecode
580.2
Nephrotic syndrome without mention of
Nephrotic syndrome without mention of glomerulonephritis
 Genitourinary 1.11 1.01 – 1.22 0.0269 468 4697 all phecode
580.3
Nephritis and nephropathy without mention of
Nephritis and nephropathy without mention of glomerulonephritis
 Genitourinary 1.09 0.961 – 1.24 0.18 246 2460 all phecode
580.32
Nephritis and nephropathy with pathological
Nephritis and nephropathy with pathological lesion
 Genitourinary 1.08 0.957 – 1.23 0.204 253 2529 all phecode
585 Renal failure Genitourinary 1.08 1.05 – 1.1 3.09e-09 6967 69751 all phecode
585.1 Acute renal failure Genitourinary 1.08 1.05 – 1.11 1.08e-06 4527 45305 all phecode
585.2 Renal failure NOS Genitourinary 1.03 0.972 – 1.08 0.361 1460 14625 all phecode
585.3 Chronic renal failure [CKD] Genitourinary 1.11 1.06 – 1.15 6.31e-07 2644 26484 all phecode
585.31 Renal dialysis Genitourinary 1.07 0.976 – 1.17 0.154 496 4955 all phecode
586 Other disorders of the kidney and ureters Genitourinary 1.03 0.993 – 1.07 0.114 3355 33580 all phecode
586.1 Anatomical abnormatilies of kidney and ureters Genitourinary 0.99 0.859 – 1.14 0.885 208 2089 all phecode
586.11 Small kidney Genitourinary 0.998 0.857 – 1.16 0.977 179 1799 all phecode
586.2 Cyst of kidney, acquired Genitourinary 0.983 0.928 – 1.04 0.572 1257 12582 all phecode
586.3 Vascular disorders of kidney/hypertrophy Genitourinary 1.02 0.814 – 1.28 0.852 80 799 all phecode
586.4 Stricture/obstruction of ureter Genitourinary 1.09 1.02 – 1.17 0.00858 910 9122 all phecode
587 Kidney replaced by transpant Genitourinary 1.02 0.917 – 1.13 0.716 368 3683 all phecode
588 Disorders resulting from impaired renal function Genitourinary 1.03 0.841 – 1.25 0.794 99 990 all phecode
589 Abnormal results of function study of kidney Genitourinary 0.901 0.749 – 1.08 0.267 116 1158 all phecode
590 Pyelonephritis Genitourinary 1.09 1.03 – 1.15 0.00342 1328 13285 all phecode
591 Urinary tract infection Genitourinary 1.04 1.02 – 1.06 5.01e-05 12400 123937 all phecode
592 Cystitis and urethritis Genitourinary 1.03 0.994 – 1.07 0.0988 2966 29661 all phecode
592.1 Cystitis Genitourinary 1.03 0.995 – 1.07 0.0915 2904 29035 all phecode
592.11 Acute cystitis Genitourinary 0.848 0.711 – 1.01 0.0671 138 1372 all phecode
592.12 Chronic cystitis Genitourinary 1.08 1.01 – 1.16 0.0229 889 8890 all phecode
592.13 Chronic interstitial cystitis Genitourinary 0.934 0.822 – 1.06 0.299 249 2486 all phecode
592.2 Urethritis and urethral syndrome Genitourinary 1.11 0.955 – 1.3 0.168 165 1662 all phecode
593 Hematuria Genitourinary 1.03 1.01 – 1.04 0.00233 16068 160204 all phecode
594 Urinary calculus Genitourinary 1.08 1.05 – 1.11 3.4e-09 6376 63761 all phecode
594.1 Calculus of kidney Genitourinary 1.07 1.03 – 1.11 0.000194 3175 31757 all phecode
594.2 Calculus of lower urinary tract Genitourinary 1.05 0.98 – 1.14 0.157 776 7764 all phecode
594.3 Calculus of ureter Genitourinary 1.08 1.04 – 1.13 0.000338 2401 24024 all phecode
594.8 Renal colic Genitourinary 1.11 1.06 – 1.16 1.35e-05 2050 20500 all phecode
595 Hydronephrosis Genitourinary 1.03 0.987 – 1.08 0.157 1936 19395 all phecode
596 Other disorders of bladder Genitourinary 1.02 0.997 – 1.04 0.09 9771 97778 all phecode
596.1 Bladder neck obstruction Genitourinary 1.04 0.998 – 1.09 0.0627 1969 19690 all phecode
596.5 Functional disorders of bladder Genitourinary 1.02 0.973 – 1.07 0.382 1658 16572 all phecode
597 Other disorders of urethra and urinary tract Genitourinary 1.03 0.995 – 1.06 0.0995 3913 39135 all phecode
597.1 Urethral stricture (not specified as infectious) Genitourinary 1.03 0.996 – 1.07 0.0842 3317 33137 all phecode
597.2 Urinary complications NEC Genitourinary 1.04 0.831 – 1.3 0.74 78 778 all phecode
598 Abnormal findings on examination of urine Genitourinary 0.985 0.952 – 1.02 0.402 3528 35302 all phecode
598.9
Other nonspecific findings on examination of
Other nonspecific findings on examination of urine
 Genitourinary 0.952 0.847 – 1.07 0.418 304 3035 all phecode
599 Other symptoms/disorders or the urinary system Genitourinary 1.02 1.01 – 1.04 0.00283 18428 184311 all phecode
599.1 Urinary obstruction Genitourinary 0.911 0.776 – 1.07 0.25 166 1670 all phecode
599.2 Retention of urine Genitourinary 1.02 0.998 – 1.05 0.0664 6718 67168 all phecode
599.3 Dysuria Genitourinary 1.01 0.952 – 1.07 0.751 1196 11967 all phecode
599.4 Urinary incontinence Genitourinary 1.02 0.995 – 1.04 0.126 8748 87477 all phecode
599.5 Frequency of urination and polyuria Genitourinary 1.01 0.975 – 1.04 0.678 4018 40144 all phecode
599.6 Oliguria and anuria Genitourinary 1.09 0.899 – 1.33 0.371 105 1059 all phecode
599.8 Other symptoms involving urinary system Genitourinary 1.09 0.846 – 1.42 0.491 62 620 all phecode
599.9 Other abnormality of urination Genitourinary 0.987 0.942 – 1.03 0.592 1913 19151 all phecode
600 Hyperplasia of prostate Genitourinary 1.01 0.987 – 1.03 0.516 11093 87892 all phecode
601 Inflammatory diseases of prostate Genitourinary 1.01 0.969 – 1.06 0.54 2081 20818 all phecode
601.1 Prostatitis Genitourinary 1.01 0.957 – 1.06 0.755 1563 15644 all phecode
601.11 Acute prostatitis Genitourinary 0.968 0.846 – 1.11 0.636 234 2358 all phecode
601.12 Chronic prostatitis Genitourinary 0.961 0.897 – 1.03 0.254 910 9089 all phecode
601.3 Orchitis and epididymitis Genitourinary 1.1 0.849 – 1.43 0.46 59 588 all phecode
601.4 Balanoposthitis Genitourinary 1.08 0.961 – 1.22 0.195 287 2864 all phecode
601.8
Other inflammatory disorders of male genital
Other inflammatory disorders of male genital organs
 Genitourinary 0.997 0.886 – 1.12 0.961 303 3019 all phecode
602 Other disorders of prostate Genitourinary 1.01 0.956 – 1.07 0.677 1341 13408 all phecode
603 Other disorders of testis Genitourinary 1.07 1.02 – 1.12 0.00425 2150 21512 all phecode
603.1 Hydrocele Genitourinary 1.05 0.991 – 1.11 0.103 1339 13402 all phecode
604 Disorders of penis Genitourinary 1.04 1.01 – 1.08 0.0254 3280 32779 all phecode
604.1 Redundant prepuce and phimosis/BXO Genitourinary 1.03 0.988 – 1.07 0.177 2719 27172 all phecode
605 Erectile dysfunction [ED] Genitourinary 1.22 1.08 – 1.38 0.0014 278 2800 all phecode
608 Other disorders of male genital organs Genitourinary 0.991 0.953 – 1.03 0.639 2822 28236 all phecode
609 Male infertility and abnormal spermatozoa Genitourinary 1.05 0.911 – 1.2 0.523 214 2138 all phecode
609.1 Infertility, male Genitourinary 0.959 0.746 – 1.23 0.745 63 638 all phecode
609.2 Abnormal spermatozoa Genitourinary 1.11 0.952 – 1.3 0.183 169 1698 all phecode
610 Benign mammary dysplasias Genitourinary 0.983 0.944 – 1.02 0.418 2482 24809 all phecode
610.1 Cystic mastopathy Genitourinary 0.968 0.905 – 1.04 0.343 925 9250 all phecode
610.2 Fibroadenosis of breast Genitourinary 1.13 1.01 – 1.27 0.035 306 3057 all phecode
610.3 Fibrosclerosis of breast Genitourinary 1.03 0.915 – 1.16 0.619 302 3018 all phecode
610.4 Benign neoplasm of breast Genitourinary 0.961 0.91 – 1.01 0.152 1388 13865 all phecode
610.8 Other specified benign mammary dysplasias Genitourinary 1.04 0.957 – 1.12 0.381 696 6954 all phecode
611 Abnormal findings on mammogram or breast exam Genitourinary 1.02 0.972 – 1.08 0.378 1574 15731 all phecode
611.1 Abnormal mammogram Genitourinary 1.4 1.06 – 1.84 0.0175 57 569 all phecode
611.3 Lump or mass in breast Genitourinary 1.02 0.966 – 1.07 0.499 1522 15213 all phecode
612
Breast conditions, congenital or relating to
Breast conditions, congenital or relating to hormones
 Genitourinary 1.04 0.967 – 1.11 0.32 887 8871 all phecode
612.2 Hypertrophy of breast (Gynecomastia) Genitourinary 1.03 0.961 – 1.11 0.39 849 8490 all phecode
612.3 Congenital anomalies of breast Genitourinary 1.08 0.849 – 1.36 0.547 72 719 all phecode
613 Other nonmalignant breast conditions Genitourinary 1 0.951 – 1.05 0.995 1651 16519 all phecode
613.1 Inflammatory disease of breast Genitourinary 1.06 0.986 – 1.15 0.112 720 7210 all phecode
613.5 Mastodynia Genitourinary 0.945 0.748 – 1.19 0.633 77 768 all phecode
613.7 Other signs and symptoms in breast Genitourinary 0.968 0.897 – 1.05 0.415 702 7013 all phecode
613.8 Other specified disorders of breast Genitourinary 1.01 0.898 – 1.13 0.925 327 3278 all phecode
613.9 Breast disorder NOS Genitourinary 0.914 0.793 – 1.05 0.214 207 2069 all phecode
614 Inflammatory diseases of female pelvic organs Genitourinary 1.04 1.01 – 1.07 0.00365 5711 57118 all phecode
614.1
Pelvic peritoneal adhesions, female
Pelvic peritoneal adhesions, female (postoperative) (postinfection)
 Genitourinary 1.05 1.01 – 1.1 0.0136 2538 25363 all phecode
614.3 Pelvic inflammatory disease (PID) Genitourinary 1.03 0.961 – 1.11 0.378 830 8308 all phecode
614.31 Acute inflammatory pelvic disease Genitourinary 1.19 0.927 – 1.53 0.17 61 608 all phecode
614.32 Chronic inflammatory pelvic disease Genitourinary 1.04 0.944 – 1.15 0.406 422 4221 all phecode
614.33 Pelvic inflammatory disease, NOS Genitourinary 1.05 0.944 – 1.18 0.346 351 3510 all phecode
614.4 Inflammatory diseases of uterus, except cervix Genitourinary 1.15 1.02 – 1.3 0.0253 277 2775 all phecode
614.5
Inflammatory disease of cervix, vagina, and
Inflammatory disease of cervix, vagina, and vulva
 Genitourinary 1.04 0.998 – 1.08 0.0656 2601 26023 all phecode
614.51 Cervicitis and endocervicitis Genitourinary 1.01 0.953 – 1.07 0.757 1318 13189 all phecode
614.52 Vaginitis and vulvovaginitis Genitourinary 1.02 0.923 – 1.13 0.681 428 4273 all phecode
614.53 Cyst or abscess of Bartholin's gland Genitourinary 1.04 0.962 – 1.12 0.343 755 7574 all phecode
614.54 Abscess or ulceration of vulva Genitourinary 1.2 1.06 – 1.36 0.00326 274 2737 all phecode
615 Endometriosis Genitourinary 1.05 1.01 – 1.08 0.0058 4029 40284 all phecode
617
Disorders secondary to childbirth, surgery
Disorders secondary to childbirth, surgery, trauma
 Genitourinary 1.17 1.04 – 1.32 0.011 304 3037 all phecode
618 Genital prolapse Genitourinary 1.05 1.03 – 1.07 4.49e-06 11689 116878 all phecode
618.1 Prolapse of vaginal walls Genitourinary 1.04 1.01 – 1.06 0.00188 7392 73940 all phecode
618.2 Uterine/Uterovaginal prolapse Genitourinary 1.06 1.03 – 1.09 0.000114 5393 53918 all phecode
618.5 Prolapse of vaginal vault after hysterectomy Genitourinary 1.08 0.99 – 1.19 0.0819 512 5125 all phecode
618.6 Vaginal enterocele, congenital or acquired Genitourinary 1.02 0.947 – 1.11 0.548 680 6794 all phecode
619 Noninflammatory female genital disorders Genitourinary 1.03 1.01 – 1.06 0.00429 8726 87297 all phecode
619.1
Noninflammatory disorders of ovary, fallopian
Noninflammatory disorders of ovary, fallopian tube, and broad ligament
 Genitourinary 1.02 0.946 – 1.1 0.603 729 7284 all phecode
619.2 Disorders of uterus, NEC Genitourinary 1.05 1.01 – 1.08 0.0133 3324 33273 all phecode
619.3 Noninflammatory disorders of cervix Genitourinary 1.02 0.982 – 1.06 0.309 2860 28608 all phecode
619.4 Noninflammatory disorders of vagina Genitourinary 0.992 0.945 – 1.04 0.762 1768 17669 all phecode
619.5 Noninflammatory disorders of vulva and perineum Genitourinary 1.05 0.993 – 1.11 0.0869 1350 13489 all phecode
620 Dysplasia of female genital organs Genitourinary 1.15 0.912 – 1.44 0.241 72 720 all phecode
621 Endometrial hyperplasia Genitourinary 1.05 0.989 – 1.12 0.11 1129 11294 all phecode
622 Polyp of female genital organs Genitourinary 1.03 1.01 – 1.05 0.0134 10480 104803 all phecode
622.1 Polyp of corpus uteri Genitourinary 1.03 1 – 1.05 0.0182 7857 78601 all phecode
622.2 Mucous polyp of cervix Genitourinary 1 0.968 – 1.04 0.886 3442 34387 all phecode
623 Hypertrophy of female genital organs Genitourinary 1.03 0.967 – 1.09 0.402 1268 12684 all phecode
624 Symptoms involving female genital tract Genitourinary 1.05 0.972 – 1.12 0.236 797 7961 all phecode
624.1 Dystrophy of female genital tract Genitourinary 1.14 1 – 1.31 0.0493 237 2365 all phecode
624.2 Atrophy of female genital tract Genitourinary 0.986 0.893 – 1.09 0.786 440 4398 all phecode
624.9 stress incontinence, female Genitourinary 1.05 1.02 – 1.08 5e-04 5865 58634 all phecode
625
Pain and other symptoms associated with female
Pain and other symptoms associated with female genital organs
 Genitourinary 1.02 0.983 – 1.06 0.285 2876 28740 all phecode
625.1 Dyspareunia Genitourinary 1.03 0.969 – 1.09 0.351 1188 11891 all phecode
626
Disorders of menstruation and other abnormal
Disorders of menstruation and other abnormal bleeding from female genital tract
 Genitourinary 1.03 1.01 – 1.04 0.0015 16168 115018 all phecode
626.1 Irregular menstrual cycle/bleeding Genitourinary 1.03 1.01 – 1.05 0.000848 14110 109918 all phecode
626.11 Absent or infrequent menstruation Genitourinary 0.919 0.757 – 1.12 0.391 109 1099 all phecode
626.12 Excessive or frequent menstruation Genitourinary 1.04 1.02 – 1.06 0.000154 9727 91749 all phecode
626.13 Irregular menstrual cycle Genitourinary 0.99 0.945 – 1.04 0.659 1985 19829 all phecode
626.14 Irregular menstrual bleeding Genitourinary 1.04 1.01 – 1.08 0.0143 3804 38021 all phecode
626.2 Dysmenorrhea Genitourinary 1.05 0.999 – 1.1 0.0569 1778 17767 all phecode
626.4 Premenstrual tension syndromes Genitourinary 0.994 0.842 – 1.17 0.945 159 1587 all phecode
626.8 Infertility, female Genitourinary 1.01 0.96 – 1.07 0.609 1362 13613 all phecode
627 Menopausal and postmenopausal disorders Genitourinary 1.04 1.02 – 1.06 0.000639 10392 103948 all phecode
627.1 Postmenopausal bleeding Genitourinary 1.04 1.01 – 1.06 0.000967 9042 90439 all phecode
627.2 Symptomatic menopause Genitourinary 1.1 0.946 – 1.28 0.219 183 1826 all phecode
627.3 Postmenopausal atrophic vaginitis Genitourinary 1.02 0.956 – 1.08 0.599 1111 11115 all phecode
627.4 Premenopausal menorrhagia Genitourinary 1.06 0.943 – 1.19 0.327 310 3097 all phecode
628 Ovarian cyst Genitourinary 1.03 0.997 – 1.06 0.0824 4747 47482 all phecode
634 Miscarriage; stillbirth Pregnancy Complications 0.973 0.945 – 1 0.0635 5218 36422 all phecode
634.1 Missed abortion/Hydatidiform mole Pregnancy Complications 0.984 0.926 – 1.04 0.594 1136 11300 all phecode
634.3 Ectopic pregnancy Pregnancy Complications 1.02 0.913 – 1.14 0.728 331 3305 all phecode
635
Hemorrhage during pregnancy; childbirth and
Hemorrhage during pregnancy; childbirth and postpartum
 Pregnancy Complications 0.965 0.921 – 1.01 0.132 1974 17372 all phecode
635.2
Antepartum hemorrhage, abruptio placentae, and
Antepartum hemorrhage, abruptio placentae, and placenta previa
 Pregnancy Complications 0.96 0.895 – 1.03 0.256 866 8614 all phecode
635.3 Placenta previa and abruptio placenta Pregnancy Complications 0.958 0.905 – 1.02 0.149 1270 12306 all phecode
636
Early or threatened labor; hemorrhage in early
Early or threatened labor; hemorrhage in early pregnancy
 Pregnancy Complications 1.02 0.978 – 1.07 0.354 2347 19972 all phecode
636.2 Early onset of delivery Pregnancy Complications 1.03 0.946 – 1.12 0.518 617 6144 all phecode
636.3 Hemorrhage in early pregnancy Pregnancy Complications 1.04 0.982 – 1.11 0.169 1082 10766 all phecode
638 Other high-risk pregnancy Pregnancy Complications 1.01 0.792 – 1.29 0.94 70 700 all phecode
642
Hypertension complicating pregnancy
Hypertension complicating pregnancy, childbirth, and the puerperium
 Pregnancy Complications 1.02 0.957 – 1.08 0.579 1110 11074 all phecode
642.1 Preeclampsia and eclampsia Pregnancy Complications 1.04 0.928 – 1.17 0.483 307 3058 all phecode
643 Excessive vomiting in pregnancy Pregnancy Complications 0.982 0.849 – 1.14 0.812 215 2149 all phecode
643.1 Hyperemesis gravidarum Pregnancy Complications 0.963 0.812 – 1.14 0.668 153 1525 all phecode
645 Late pregnancy and failed induction Pregnancy Complications 0.96 0.905 – 1.02 0.167 1250 12450 all phecode
646 Other complications of pregnancy NEC Pregnancy Complications 0.989 0.947 – 1.03 0.628 2228 20847 all phecode
647
Infectious and parasitic complications
Infectious and parasitic complications affecting pregnancy
 Pregnancy Complications 1.41 1.08 – 1.84 0.0104 68 679 all phecode
647.1
Infections of genitourinary tract during
Infections of genitourinary tract during pregnancy
 Pregnancy Complications 0.963 0.852 – 1.09 0.545 275 2748 all phecode
649
Other conditions or status of the mother
Other conditions or status of the mother complicating pregnancy, childbirth, or the puerperium
 Pregnancy Complications 0.954 0.784 – 1.16 0.639 113 1129 all phecode
649.1
Diabetes or abnormal glucose tolerance
Diabetes or abnormal glucose tolerance complicating pregnancy
 Pregnancy Complications 1.24 1.07 – 1.44 0.00434 193 1922 all phecode
650 Normal delivery Pregnancy Complications 0.948 0.904 – 0.993 0.0245 1922 18973 all phecode
651 Multiple gestation Pregnancy Complications 0.978 0.875 – 1.09 0.692 346 3454 all phecode
652
Malposition and malpresentation of fetus or
Malposition and malpresentation of fetus or obstruction
 Pregnancy Complications 0.969 0.922 – 1.02 0.223 1716 16521 all phecode
653
Problems associated with amniotic cavity and
Problems associated with amniotic cavity and membranes
 Pregnancy Complications 0.975 0.923 – 1.03 0.357 1401 13649 all phecode
654
Other and unspecified complications of birth
Other and unspecified complications of birth; puerperium affecting management of mother
 Pregnancy Complications 1.02 0.813 – 1.29 0.847 74 739 all phecode
655
Known or suspected fetal abnormality affecting
Known or suspected fetal abnormality affecting management of mother
 Pregnancy Complications 0.964 0.934 – 0.996 0.028 4306 29454 all phecode
656 Other perinatal conditions of fetus or newborn Pregnancy Complications 1.05 0.862 – 1.27 0.654 109 1080 all phecode
661 Fetal distress and abnormal forces of labor Pregnancy Complications 0.982 0.94 – 1.03 0.409 2265 18397 all phecode
663
Umbilical cord complications during labor and
Umbilical cord complications during labor and delivery
 Pregnancy Complications 1.03 0.947 – 1.13 0.452 532 5316 all phecode
665 Obstetrical/birth trauma Pregnancy Complications 0.956 0.928 – 0.985 0.00338 5313 29472 all phecode
669 Complications of labor and delivery NEC Pregnancy Complications 0.961 0.922 – 1 0.0564 2552 21174 all phecode
671
Venous/cerebrovascular complications embolism
Venous/cerebrovascular complications embolism in pregnancy and the puerperium
 Pregnancy Complications 0.99 0.846 – 1.16 0.902 164 1628 all phecode
674 Other complications of the puerperium NEC Pregnancy Complications 1.17 1.03 – 1.33 0.0177 262 2605 all phecode
676
Other disorders of the breast associated with
Other disorders of the breast associated with childbirth and disorders of lactation
 Pregnancy Complications 0.91 0.7 – 1.18 0.48 63 624 all phecode
679 Complications of in utero procedures Dermatologic 0.865 0.659 – 1.14 0.298 53 530 all phecode
681 Superficial cellulitis and abscess Dermatologic 1.02 0.993 – 1.04 0.162 7200 72225 all phecode
681.1 Cellulitis and abscess of fingers/toes Dermatologic 1.03 0.943 – 1.12 0.528 563 5647 all phecode
681.2 Cellulitis and abscess of face/neck Dermatologic 1.05 0.957 – 1.15 0.312 520 5208 all phecode
681.3 Cellulitis and abscess of arm/hand Dermatologic 1.01 0.979 – 1.03 0.659 5481 55014 all phecode
681.5 Cellulitis and abscess of leg, except foot Dermatologic 1.01 0.98 – 1.04 0.585 5487 55074 all phecode
681.6 Cellulitis and abscess of foot, toe Dermatologic 1.01 0.979 – 1.04 0.623 5444 54643 all phecode
681.7 Cellulitis and abscess of trunk Dermatologic 1.05 0.963 – 1.14 0.274 597 5987 all phecode
686
Other local infections of skin and subcutaneous
Other local infections of skin and subcutaneous tissue
 Dermatologic 1.08 1.02 – 1.15 0.00548 1337 13427 all phecode
686.1 Carbuncle and furuncle Dermatologic 1.03 0.984 – 1.07 0.223 2284 22925 all phecode
686.3 Pilonidal cyst Dermatologic 1.06 0.973 – 1.15 0.18 583 5837 all phecode
686.4 Pyogenic granuloma Dermatologic 1.07 0.958 – 1.2 0.232 362 3615 all phecode
687 Symptoms affecting skin Dermatologic 0.976 0.893 – 1.07 0.586 548 5508 all phecode
687.1 Rash and other nonspecific skin eruption Dermatologic 0.95 0.909 – 0.993 0.0242 2146 21470 all phecode
687.2 Localized superficial swelling, mass, or lump Dermatologic 1.03 0.909 – 1.16 0.678 283 2839 all phecode
687.3 Changes in skin texture Dermatologic 0.816 0.671 – 0.992 0.0409 106 1070 all phecode
687.4 Disturbance of skin sensation Dermatologic 1.03 0.992 – 1.07 0.116 2884 28859 all phecode
689 Disorder of skin and subcutaneous tissue NOS Dermatologic 1.02 0.994 – 1.05 0.124 5747 57521 all phecode
690 Erythematosquamous dermatosis Dermatologic 0.849 0.665 – 1.09 0.191 71 710 all phecode
690.1 Seborrheic dermatitis Dermatologic 0.718 0.537 – 0.96 0.0252 53 530 all phecode
691 Congenital anomalies of skin Dermatologic 0.988 0.824 – 1.18 0.895 120 1199 all phecode
694 Dyschromia and Vitiligo Dermatologic 1.01 0.948 – 1.08 0.719 986 9854 all phecode
694.1 Vitiligo Dermatologic 1.02 0.78 – 1.32 0.906 60 599 all phecode
694.2 Other dyschromia Dermatologic 1.02 0.952 – 1.1 0.512 782 7821 all phecode
694.3 Vascular disorders of skin Dermatologic 0.958 0.793 – 1.16 0.651 117 1170 all phecode
695 Erythematous conditions Dermatologic 1.05 1.01 – 1.1 0.0198 2379 23813 all phecode
695.1 Toxic erythema Dermatologic 0.995 0.824 – 1.2 0.959 109 1090 all phecode
695.2 Bullous dermatoses Dermatologic 1.01 0.845 – 1.21 0.901 137 1365 all phecode
695.21 Dermatitis herpetiformis Dermatologic 0.93 0.706 – 1.23 0.608 57 569 all phecode
695.22 Pemphigus and pemphigoid Dermatologic 0.943 0.739 – 1.2 0.638 73 727 all phecode
695.3 Rosacea Dermatologic 1.22 1.08 – 1.38 0.00109 309 3097 all phecode
695.4 Lupus (localized and systemic) Dermatologic 0.958 0.866 – 1.06 0.402 411 4114 all phecode
695.41 Cutaneous lupus erythematosus Dermatologic 0.843 0.705 – 1.01 0.061 130 1295 all phecode
695.42 Systemic lupus erythematosus Dermatologic 0.995 0.891 – 1.11 0.929 340 3407 all phecode
695.7 Prurigo and Lichen Dermatologic 1.05 0.975 – 1.13 0.204 775 7760 all phecode
695.8 Other specified erythematous conditions Dermatologic 1.2 1.05 – 1.37 0.00783 236 2359 all phecode
695.81 Erythema nodosum Dermatologic 1.27 1 – 1.61 0.0491 76 760 all phecode
695.9 Unspecified erythematous condition Dermatologic 1 0.913 – 1.1 0.942 467 4672 all phecode
696 Psoriasis and related disorders Dermatologic 1.06 1.01 – 1.11 0.00897 2252 22509 all phecode
696.4 Psoriasis Dermatologic 1.06 1.02 – 1.11 0.00608 2198 21969 all phecode
696.41 Psoriasis vulgaris Dermatologic 1.06 1.01 – 1.12 0.0201 1680 16796 all phecode
696.42 Psoriatic arthropathy Dermatologic 1.05 0.973 – 1.13 0.211 706 7052 all phecode
697 Sarcoidosis Dermatologic 1.08 0.985 – 1.18 0.104 539 5373 all phecode
698 Pruritus and related conditions Dermatologic 1.03 0.956 – 1.11 0.443 782 7814 all phecode
700 Corns and callosities Dermatologic 0.979 0.87 – 1.1 0.731 291 2904 all phecode
701
Other hypertrophic and atrophic conditions of
Other hypertrophic and atrophic conditions of skin
 Dermatologic 1.01 0.978 – 1.04 0.595 4663 46650 all phecode
701.1 Keratoderma, acquired Dermatologic 1.03 0.827 – 1.28 0.79 87 870 all phecode
701.2 Scar conditions and fibrosis of skin Dermatologic 0.998 0.956 – 1.04 0.919 2348 23478 all phecode
701.3 Circumscribed scleroderma Dermatologic 1.09 0.839 – 1.42 0.514 61 610 all phecode
701.4 Keloid scar Dermatologic 1.04 0.909 – 1.2 0.538 216 2159 all phecode
701.5 Abnormal granulation tissue Dermatologic 0.965 0.878 – 1.06 0.466 455 4568 all phecode
701.6 Acquired acanthosis nigricans Dermatologic 1.17 0.961 – 1.43 0.116 102 1019 all phecode
702
Degenerative skin conditions and other
Degenerative skin conditions and other dermatoses
 Dermatologic 1.02 0.989 – 1.05 0.227 5459 54587 all phecode
702.1 Actinic keratosis Dermatologic 1.01 0.967 – 1.05 0.743 2585 25842 all phecode
702.2 Seborrheic keratosis Dermatologic 1.03 0.991 – 1.07 0.139 3078 30772 all phecode
703 Diseases of nail, NOS Dermatologic 1.02 0.917 – 1.14 0.679 354 3539 all phecode
703.1 Ingrowing nail Dermatologic 1.02 0.959 – 1.09 0.478 966 9660 all phecode
704 Diseases of hair and hair follicles Dermatologic 1.04 1.01 – 1.07 0.0172 5267 52727 all phecode
704.1 Alopecia Dermatologic 1.16 0.965 – 1.4 0.112 125 1269 all phecode
704.8
Other specified diseases of hair and hair
Other specified diseases of hair and hair follicles
 Dermatologic 1.06 0.847 – 1.34 0.594 76 759 all phecode
705 Disorders of sweat glands Dermatologic 1.05 0.918 – 1.2 0.474 228 2287 all phecode
705.3 Hidradenitis Dermatologic 1.02 0.876 – 1.19 0.805 186 1868 all phecode
705.8 Hyperhidrosis Dermatologic 1.07 0.982 – 1.16 0.122 591 5919 all phecode
706 Diseases of sebaceous glands Dermatologic 1.03 1.01 – 1.06 0.00436 8317 83195 all phecode
706.1 Acne Dermatologic 1.17 0.93 – 1.48 0.178 78 779 all phecode
706.2 Sebaceous cyst Dermatologic 1.03 1.01 – 1.06 0.00436 8787 87882 all phecode
707 Chronic ulcer of skin Dermatologic 1.08 1.03 – 1.13 0.00139 1953 19654 all phecode
707.1 Decubitus ulcer Dermatologic 0.994 0.928 – 1.07 0.871 909 9097 all phecode
709 Diffuse diseases of connective tissue Dermatologic 1.05 1.01 – 1.08 0.0101 3432 34317 all phecode
709.2 Sicca syndrome Dermatologic 0.998 0.91 – 1.09 0.961 508 5073 all phecode
709.3 Systemic sclerosis Dermatologic 0.955 0.818 – 1.12 0.563 176 1753 all phecode
709.6
Other specified diffuse diseases of connective
Other specified diffuse diseases of connective tissue
 Dermatologic 1.03 0.795 – 1.32 0.844 65 649 all phecode
709.7 Unspecified diffuse connective tissue disease Dermatologic 1.06 1.02 – 1.1 0.00698 2714 27144 all phecode
710
Osteomyelitis, periostitis, and other
Osteomyelitis, periostitis, and other infections involving bone
 Musculoskeletal 1.14 1.05 – 1.24 0.00194 602 6034 all phecode
710.1 Osteomyelitis Musculoskeletal 1.17 1.07 – 1.28 0.00051 556 5574 all phecode
710.12 Chronic osteomyelitis Musculoskeletal 1.13 0.972 – 1.31 0.113 194 1947 all phecode
710.19 Unspecified osteomyelitis Musculoskeletal 1.19 1.08 – 1.32 0.000828 398 3997 all phecode
711 Arthropathy associated with infections Musculoskeletal 1.03 0.928 – 1.14 0.609 421 4225 all phecode
711.1 Pyogenic arthritis Musculoskeletal 1.09 0.967 – 1.22 0.164 328 3296 all phecode
712 Infective connective tissue disorders Musculoskeletal 1.1 0.883 – 1.38 0.385 81 810 all phecode
713
Arthropathy associated with other disorders
Arthropathy associated with other disorders classified elsewhere
 Musculoskeletal 1.06 0.899 – 1.26 0.471 148 1499 all phecode
713.5
Arthropathy associated with neurological
Arthropathy associated with neurological disorders
 Musculoskeletal 1.71 1.31 – 2.23 8.29e-05 65 669 all phecode
714
Rheumatoid arthritis and other inflammatory
Rheumatoid arthritis and other inflammatory polyarthropathies
 Musculoskeletal 1.09 1.06 – 1.12 1.93e-08 4832 48320 all phecode
714.1 Rheumatoid arthritis Musculoskeletal 1.1 1.07 – 1.14 4.04e-10 4372 43714 all phecode
715 Other inflammatory spondylopathies Musculoskeletal 1 0.955 – 1.06 0.858 1659 16588 all phecode
715.1 Sacroiliitis NEC Musculoskeletal 1.06 0.874 – 1.28 0.557 113 1129 all phecode
715.2 Ankylosing spondylitis Musculoskeletal 0.996 0.916 – 1.08 0.916 618 6177 all phecode
716 Other arthropathies Musculoskeletal 1.03 1.02 – 1.04 1.69e-08 37478 265375 all phecode
716.1 Unspecified polyarthropathy or polyarthritis Musculoskeletal 1.05 1.02 – 1.09 0.00351 3505 35090 all phecode
716.2 Unspecified monoarthritis Musculoskeletal 1.03 1.01 – 1.05 0.000341 15522 155339 all phecode
716.9 Arthropathy NOS Musculoskeletal 1.03 1.02 – 1.04 2.4e-08 35944 262308 all phecode
717 Polymyalgia Rheumatica Musculoskeletal 1.08 1.01 – 1.14 0.0184 1145 11480 all phecode
720 Spinal stenosis Musculoskeletal 1.04 1 – 1.07 0.0431 3705 37091 all phecode
721 Spondylosis and allied disorders Musculoskeletal 1.04 1.01 – 1.06 0.00299 7832 78318 all phecode
721.1 Spondylosis without myelopathy Musculoskeletal 1.04 1.01 – 1.07 0.00488 5045 50451 all phecode
721.2 Spondylosis with myelopathy Musculoskeletal 1.18 1.01 – 1.37 0.0346 189 1899 all phecode
721.8 Other allied disorders of spine Musculoskeletal 1.04 0.934 – 1.16 0.458 352 3519 all phecode
722 Intervertebral disc disorders Musculoskeletal 1.05 1.02 – 1.07 3e-05 8978 89848 all phecode
722.1 Displacement of intervertebral disc Musculoskeletal 1.07 0.977 – 1.17 0.149 512 5116 all phecode
722.6 Degeneration of intervertebral disc Musculoskeletal 1.05 1.01 – 1.09 0.017 2831 28328 all phecode
722.8 Postlaminectomy syndrome Musculoskeletal 1.09 0.857 – 1.39 0.481 67 669 all phecode
722.9 Other and unspecified disc disorder Musculoskeletal 1.04 1.01 – 1.07 0.019 4407 44127 all phecode
723 Other disorders of cervical region Musculoskeletal 1.15 1.05 – 1.26 0.00215 517 5173 all phecode
723.1 Torticollis Musculoskeletal 1.25 1.03 – 1.52 0.0255 107 1068 all phecode
724 Other and unspecified disorders of back Musculoskeletal 1.02 0.977 – 1.07 0.345 2052 20514 all phecode
724.1 Disorders of sacrum Musculoskeletal 1.05 0.947 – 1.16 0.357 403 4024 all phecode
724.2 Disorders of coccyx Musculoskeletal 1.05 0.951 – 1.17 0.312 406 4054 all phecode
724.8 Other symptoms referable to back Musculoskeletal 1.4 1.08 – 1.82 0.0124 63 630 all phecode
724.9 Other unspecified back disorders Musculoskeletal 1 0.953 – 1.05 0.926 1614 16139 all phecode
726 Peripheral enthesopathies and allied syndromes Musculoskeletal 1.04 1.03 – 1.06 8.08e-07 14663 146691 all phecode
726.1 Enthesopathy Musculoskeletal 1.04 1.02 – 1.06 0.000152 9589 95900 all phecode
726.2 Synoviopathy Musculoskeletal 1.09 0.977 – 1.22 0.123 334 3336 all phecode
726.3 Bursitis Musculoskeletal 1.11 1.03 – 1.19 0.00408 854 8573 all phecode
727 Other disorders of synovium, tendon, and bursa Musculoskeletal 1.04 1.01 – 1.06 0.00169 7331 73332 all phecode
727.1 Synovitis and tenosynovitis Musculoskeletal 1.06 1.02 – 1.1 0.00537 2737 27406 all phecode
727.2 Bursitis disorders Musculoskeletal 0.987 0.81 – 1.2 0.895 103 1029 all phecode
727.4 Ganglion and cyst of synovium, tendon, and bursa Musculoskeletal 1.04 0.998 – 1.08 0.0611 3109 31085 all phecode
727.5 Rupture of synovium Musculoskeletal 0.983 0.903 – 1.07 0.685 586 5854 all phecode
727.6 Rupture of tendon, nontraumatic Musculoskeletal 1.01 0.909 – 1.13 0.805 353 3527 all phecode
727.7 Contracture of tendon (sheath) Musculoskeletal 1.02 0.863 – 1.21 0.792 143 1429 all phecode
728 Disorders of muscle, ligament, and fascia Musculoskeletal 1.07 1.04 – 1.11 5.53e-05 3677 36788 all phecode
728.2 Laxity of ligament or hypermobility syndrome Musculoskeletal 0.989 0.895 – 1.09 0.835 412 4115 all phecode
728.7 Fasciitis Musculoskeletal 1.08 1.05 – 1.12 5.25e-06 3803 38045 all phecode
728.71
Contracture of palmar fascia [Dupuytren's
Contracture of palmar fascia [Dupuytren's disease]
 Musculoskeletal 1.08 1.04 – 1.12 2.61e-05 3477 34788 all phecode
729 Other disorders of soft tissues Musculoskeletal 1.04 1.01 – 1.07 0.00473 6014 60309 all phecode
729.1 Rheumatism, unspecified and fibrositis Musculoskeletal 1.05 0.988 – 1.12 0.111 1005 10063 all phecode
729.3 Panniculitis Musculoskeletal 1.02 0.83 – 1.26 0.843 101 1009 all phecode
731
Osteitis deformans and osteopathies associated
Osteitis deformans and osteopathies associated with other disorders classified elsewhere
 Musculoskeletal 1.13 1 – 1.28 0.0488 276 2758 all phecode
731.1 Osteitis deformans [Paget's disease of bone] Musculoskeletal 1.12 0.991 – 1.28 0.0699 261 2609 all phecode
732 Osteochondropathies Musculoskeletal 1.02 0.926 – 1.12 0.692 467 4679 all phecode
732.1 Juvenile osteochondrosis Musculoskeletal 1.08 0.937 – 1.24 0.29 207 2068 all phecode
732.7 Osteochondritis dissecans Musculoskeletal 0.83 0.632 – 1.09 0.182 57 570 all phecode
733 Other disorders of bone and cartilage Musculoskeletal 1.01 0.961 – 1.06 0.709 1777 17814 all phecode
733.2 Cyst of bone Musculoskeletal 0.969 0.862 – 1.09 0.596 311 3115 all phecode
733.4 Aseptic necrosis of bone Musculoskeletal 0.99 0.907 – 1.08 0.823 540 5393 all phecode
733.6 Costochondritis Musculoskeletal 1.1 0.916 – 1.32 0.313 128 1276 all phecode
733.8 Malunion and nonunion of fracture Musculoskeletal 1.03 0.97 – 1.09 0.347 1231 12313 all phecode
733.9 Chondromalacia Musculoskeletal 1.16 0.957 – 1.41 0.13 121 1206 all phecode
735 Acquired foot deformities Musculoskeletal 1.01 0.986 – 1.03 0.542 9603 96090 all phecode
735.1 Flat foot Musculoskeletal 1.1 0.945 – 1.27 0.225 189 1910 all phecode
735.2 Acquired toe deformities Musculoskeletal 0.989 0.96 – 1.02 0.434 5070 50712 all phecode
735.21 Hammer toe (acquired) Musculoskeletal 0.973 0.928 – 1.02 0.254 1929 19324 all phecode
735.23 Hallux rigidus Musculoskeletal 1 0.954 – 1.06 0.861 1555 15527 all phecode
735.3 Hallux valgus (Bunion) Musculoskeletal 1 0.979 – 1.03 0.76 6643 66463 all phecode
736 Other acquired deformities of limbs Musculoskeletal 1.04 0.989 – 1.1 0.121 1627 16282 all phecode
736.2 Acquired deformities of finger Musculoskeletal 0.964 0.846 – 1.1 0.587 248 2476 all phecode
737 Curvature of spine Musculoskeletal 0.968 0.91 – 1.03 0.309 1128 11300 all phecode
737.3 Kyphoscoliosis and scoliosis Musculoskeletal 0.956 0.897 – 1.02 0.169 1061 10632 all phecode
738 Other acquired musculoskeletal deformity Musculoskeletal 0.995 0.949 – 1.04 0.829 1904 19058 all phecode
738.4 Acquired spondylolisthesis Musculoskeletal 0.99 0.939 – 1.04 0.718 1513 15147 all phecode
739 Contracture of joint Musculoskeletal 1.1 1 – 1.21 0.0467 488 4884 all phecode
740 Osteoarthrosis Musculoskeletal 1.01 0.997 – 1.02 0.118 27707 231603 all phecode
740.1 Osteoarthritis; localized Musculoskeletal 1 0.989 – 1.02 0.595 17412 169419 all phecode
740.11 Osteoarthrosis, localized, primary Musculoskeletal 1.01 0.986 – 1.03 0.502 8974 89750 all phecode
740.12 Osteoarthrosis, localized, secondary Musculoskeletal 1 0.901 – 1.12 0.933 348 3474 all phecode
740.2 Osteoarthrosis, generalized Musculoskeletal 1 0.921 – 1.09 0.977 598 5969 all phecode
740.9 Osteoarthrosis NOS Musculoskeletal 1.02 1 – 1.04 0.0446 12270 122792 all phecode
741 Symptoms and disorders of the joints Musculoskeletal 1.05 1.02 – 1.09 0.0024 3563 35648 all phecode
741.1 Ankylosis of joint Musculoskeletal 1.14 0.935 – 1.39 0.193 102 1019 all phecode
741.2 Stiffness of joint Musculoskeletal 1.12 1.03 – 1.22 0.00635 614 6146 all phecode
741.3 Difficulty in walking Musculoskeletal 1.01 0.855 – 1.19 0.926 154 1540 all phecode
741.4 Joint effusions Musculoskeletal 1.04 0.989 – 1.1 0.118 1418 14197 all phecode
741.5 Hemarthrosis Musculoskeletal 1.1 0.912 – 1.34 0.309 110 1100 all phecode
741.6 Villonodular synovitis Musculoskeletal 1.19 0.901 – 1.56 0.223 54 535 all phecode
742 Derangement of joint, non-traumatic Musculoskeletal 1.02 0.986 – 1.07 0.211 2843 28441 all phecode
742.1 Loose body in joint Musculoskeletal 0.963 0.862 – 1.08 0.513 333 3337 all phecode
742.2
Pathological, developmental or recurrent
Pathological, developmental or recurrent dislocation
 Musculoskeletal 1.2 0.972 – 1.47 0.0913 95 960 all phecode
742.8 Articular cartilage disorder Musculoskeletal 1.05 0.956 – 1.15 0.318 500 4996 all phecode
742.9 Other derangement of joint Musculoskeletal 1.02 0.975 – 1.07 0.375 1993 19926 all phecode
743
Osteoporosis, osteopenia and pathological
Osteoporosis, osteopenia and pathological fracture
 Musculoskeletal 0.997 0.974 – 1.02 0.822 7563 75729 all phecode
743.1 Osteoporosis Musculoskeletal 0.992 0.967 – 1.02 0.528 6400 64107 all phecode
743.11 Osteoporosis NOS Musculoskeletal 0.989 0.962 – 1.02 0.419 5549 55604 all phecode
743.13 Other specified osteoporosis Musculoskeletal 1.04 0.952 – 1.14 0.375 529 5283 all phecode
743.2 Pathologic fracture Musculoskeletal 0.986 0.901 – 1.08 0.765 516 5179 all phecode
743.9
Osteopenia or other disorder of bone and
Osteopenia or other disorder of bone and cartilage
 Musculoskeletal 1.02 0.944 – 1.09 0.684 815 8144 all phecode
745 Pain in joint Musculoskeletal 1.03 1 – 1.05 0.0181 7975 79789 all phecode
747 Cardiac and circulatory congenital anomalies Congenital Anomalies 1.02 0.983 – 1.06 0.269 2802 28058 all phecode
747.1 Cardiac congenital anomalies Congenital Anomalies 1.03 0.988 – 1.07 0.177 2628 26323 all phecode
747.11 Cardiac shunt/ heart septal defect Congenital Anomalies 0.96 0.882 – 1.05 0.348 584 5838 all phecode
747.12 Valvular heart disease/ heart chambers Congenital Anomalies 0.895 0.786 – 1.02 0.0973 235 2358 all phecode
747.13 Congenital anomalies of great vessels Congenital Anomalies 1.07 1.02 – 1.12 0.00581 1816 18200 all phecode
747.2
Congenital anomalies of peripheral vascular
Congenital anomalies of peripheral vascular system
 Congenital Anomalies 0.899 0.767 – 1.05 0.191 167 1680 all phecode
748 Anomalies of respiratory system, congenital Congenital Anomalies 0.934 0.716 – 1.22 0.613 51 510 all phecode
749 Congenital anomalies of face and neck Congenital Anomalies 0.933 0.829 – 1.05 0.25 303 3029 all phecode
750 Digestive congenital anomalies Congenital Anomalies 0.922 0.851 – 0.998 0.0442 686 6870 all phecode
750.1 Upper gastrointestinal congenital anomalies Congenital Anomalies 0.954 0.85 – 1.07 0.43 327 3263 all phecode
750.13 Congenital anomalies of mouth/tongue Congenital Anomalies 1.03 0.886 – 1.2 0.685 191 1909 all phecode
750.2 Lower gastrointestinal congenital anomalies Congenital Anomalies 0.895 0.801 – 1 0.0494 356 3574 all phecode
750.21 Congenital anomalies of intestine Congenital Anomalies 0.884 0.771 – 1.01 0.0791 225 2256 all phecode
750.22
Congenital anomaly of gallbladder, bile ducts
Congenital anomaly of gallbladder, bile ducts, liver, pancreas
 Congenital Anomalies 0.92 0.758 – 1.12 0.395 117 1179 all phecode
751 Genitourinary congenital anomalies Congenital Anomalies 0.972 0.922 – 1.02 0.287 1527 15286 all phecode
751.1 Congenital anomalies of genital organs Congenital Anomalies 0.995 0.92 – 1.08 0.911 694 6932 all phecode
751.11 Congenital anomalies of female genital organs Congenital Anomalies 0.996 0.904 – 1.1 0.942 455 4546 all phecode
751.12 Congenital anomalies of male genital organs Congenital Anomalies 0.968 0.84 – 1.12 0.658 222 2217 all phecode
751.2 Congenital anomalies of urinary system Congenital Anomalies 0.959 0.893 – 1.03 0.25 836 8385 all phecode
751.21 Cystic kidney disease Congenital Anomalies 0.979 0.885 – 1.08 0.685 424 4246 all phecode
751.22 Other specified congenital anomalies of kidney Congenital Anomalies 0.983 0.88 – 1.1 0.759 333 3346 all phecode
752 Nervous system congenital anomalies Congenital Anomalies 1.03 0.916 – 1.15 0.644 328 3307 all phecode
752.1 Neural tube defects Congenital Anomalies 1.01 0.888 – 1.15 0.875 253 2557 all phecode
752.11 Spina bifida Congenital Anomalies 0.979 0.85 – 1.13 0.77 208 2108 all phecode
752.2
Other specified congenital anomalies of nervous
Other specified congenital anomalies of nervous system
 Congenital Anomalies 0.95 0.752 – 1.2 0.666 78 780 all phecode
753 Congenital anomalies of the eye Congenital Anomalies 1.19 0.991 – 1.43 0.0619 127 1270 all phecode
753.1 Congenital cataract and lens anomalies Congenital Anomalies 1.23 0.974 – 1.56 0.081 76 760 all phecode
754 Congenital musculoskeletal deformities of spine Congenital Anomalies 1.11 0.916 – 1.34 0.289 109 1099 all phecode
755 Congenital anomalies of limbs Congenital Anomalies 1.01 0.917 – 1.12 0.795 425 4276 all phecode
755.1 Congenital deformities of feet Congenital Anomalies 1.03 0.9 – 1.18 0.647 208 2086 all phecode
755.6
Other congenital anomalies of lower limb
Other congenital anomalies of lower limb, including pelvic girdle
 Congenital Anomalies 0.924 0.782 – 1.09 0.348 160 1620 all phecode
755.61 Congenital hip dysplasia and deformity Congenital Anomalies 0.956 0.777 – 1.18 0.672 106 1070 all phecode
756 Other congenital musculoskeletal anomalies Congenital Anomalies 1.01 0.933 – 1.1 0.729 587 5872 all phecode
756.3
Congenital anomalies of muscle, tendon, fascia
Congenital anomalies of muscle, tendon, fascia, and connective tissue
 Congenital Anomalies 0.999 0.799 – 1.25 0.992 81 810 all phecode
756.5 Congenital osteodystrophies Congenital Anomalies 1.04 0.943 – 1.15 0.428 435 4356 all phecode
758 Chromosomal anomalies and genetic disorders Congenital Anomalies 0.971 0.825 – 1.14 0.722 148 1708 all phecode
758.1 Chromosomal anomalies Congenital Anomalies 0.938 0.728 – 1.21 0.619 60 830 all phecode
759 Other and unspecified congenital anomalies Congenital Anomalies 1 0.871 – 1.15 0.995 216 2159 all phecode
759.1 Anomalies of endocrine glands, congenital Congenital Anomalies 0.905 0.736 – 1.11 0.348 96 959 all phecode
760 Back pain Symptoms 1.04 1.02 – 1.06 0.00036 11126 111353 all phecode
761 Cervicalgia Symptoms 1.04 0.995 – 1.1 0.0772 1791 17901 all phecode
764 Sciatica Symptoms 1.04 1 – 1.09 0.0483 2372 23732 all phecode
766 Neuralgia, neuritis, and radiculitis NOS Symptoms 1.01 0.952 – 1.07 0.705 1172 11738 all phecode
770 Myalgia and myositis unspecified Symptoms 1.03 0.948 – 1.11 0.51 631 6311 all phecode
771 Musculoskeletal symptoms referable to limbs Symptoms 1.08 1 – 1.15 0.038 870 8687 all phecode
771.1 Swelling of limb Symptoms 1.03 1 – 1.06 0.0523 4617 46330 all phecode
772 Symptoms of the muscles Symptoms 1.03 0.946 – 1.11 0.546 659 6581 all phecode
773 Pain in limb Symptoms 1.03 0.999 – 1.05 0.0627 6209 62203 all phecode
780 Hypothermia/Chills Symptoms 0.989 0.844 – 1.16 0.891 171 1719 all phecode
781
Symptoms involving nervous and musculoskeletal
Symptoms involving nervous and musculoskeletal systems
 Symptoms 1.01 0.962 – 1.06 0.705 1870 18715 all phecode
782.3 Edema Symptoms 1.06 1.01 – 1.12 0.0217 1642 16450 all phecode
782.6 Pallor and flushing Symptoms 1.16 0.991 – 1.35 0.0652 175 1748 all phecode
783 Fever of unknown origin Symptoms 1.04 1 – 1.07 0.0291 3911 39105 all phecode
785 Abdominal pain Symptoms 1.03 1.02 – 1.04 5.77e-09 40080 301686 all phecode
788 Syncope and collapse Symptoms 1.03 1.01 – 1.05 0.0109 9069 90813 all phecode
789 Nausea and vomiting Symptoms 1.05 1.03 – 1.07 1.27e-06 11577 115807 all phecode
790 Nonspecific findings on examination of blood Symptoms 0.992 0.836 – 1.18 0.93 150 1500 all phecode
790.1 Elevated sedimentation rate Symptoms 0.964 0.775 – 1.2 0.745 84 840 all phecode
790.6 Other abnormal blood chemistry Symptoms 1 0.979 – 1.03 0.71 6357 63635 all phecode
791 Gangrene Symptoms 1.15 1.05 – 1.26 0.00161 549 5501 all phecode
792
Abnormal Papanicolaou smear of cervix and
Abnormal Papanicolaou smear of cervix and cervical HPV
 Symptoms 0.896 0.724 – 1.11 0.317 98 966 all phecode
793
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of musculoskeletal system
 Symptoms 1.04 0.873 – 1.24 0.667 134 1340 all phecode
793.2
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of other intrathoracic organs (echocardiogram, etc)
 Symptoms 1.03 0.943 – 1.12 0.539 565 5647 all phecode
794
Abnormal results of other function studies
Abnormal results of other function studies (bladder, pancreas, placenta, spleen, etc)
 Symptoms 0.976 0.807 – 1.18 0.801 120 1198 all phecode
797 Shock Symptoms 1.01 0.858 – 1.19 0.898 156 1559 all phecode
797.1 Cardiogenic shock Symptoms 1 0.815 – 1.23 0.997 102 1020 all phecode
798 Malaise and fatigue Symptoms 1.03 0.999 – 1.07 0.0591 3408 34103 all phecode
798.1 Chronic fatigue syndrome Symptoms 1.02 0.938 – 1.11 0.635 591 5913 all phecode
800 Fracture of lower limb Injuries & Poisonings 1.02 0.991 – 1.04 0.222 7035 70329 all phecode
800.1 Fracture of neck of femur Injuries & Poisonings 0.966 0.921 – 1.01 0.16 1815 18152 all phecode
800.2 Fracture of unspecified part of femur Injuries & Poisonings 1.04 0.887 – 1.21 0.647 170 1693 all phecode
800.3 Fracture of tibia and fibula Injuries & Poisonings 1.02 0.977 – 1.07 0.36 2158 21577 all phecode
800.4 Fracture of patella Injuries & Poisonings 1.09 1.01 – 1.17 0.022 766 7661 all phecode
801 Fracture of ankle and foot Injuries & Poisonings 1.04 0.992 – 1.08 0.11 2205 22041 all phecode
801.1 Fracture of foot Injuries & Poisonings 1.05 0.997 – 1.1 0.0673 1835 18346 all phecode
802 Fracture of pelvis Injuries & Poisonings 1.01 0.93 – 1.09 0.896 718 7185 all phecode
803 Fracture of upper limb Injuries & Poisonings 0.97 0.948 – 0.992 0.00706 8288 82880 all phecode
803.1 Fracture of humerus Injuries & Poisonings 0.996 0.948 – 1.05 0.887 1691 16883 all phecode
803.2 Fracture of radius and ulna Injuries & Poisonings 0.957 0.93 – 0.985 0.00243 5215 52171 all phecode
803.3 Fracture of clavicle or scapula Injuries & Poisonings 0.978 0.928 – 1.03 0.411 1518 15186 all phecode
804 Fracture of hand or wrist Injuries & Poisonings 1 0.966 – 1.04 0.975 3339 33384 all phecode
805
Fracture of vertebral column without mention of
Fracture of vertebral column without mention of spinal cord injury
 Injuries & Poisonings 0.983 0.93 – 1.04 0.554 1358 13565 all phecode
807 Fracture of ribs Injuries & Poisonings 1.04 0.964 – 1.12 0.325 776 7752 all phecode
809 Fracture of unspecified bones Injuries & Poisonings 0.96 0.907 – 1.02 0.154 1300 12998 all phecode
817 Concussion Injuries & Poisonings 0.935 0.821 – 1.07 0.315 243 2428 all phecode
818 Intracranial hemorrhage (injury) Injuries & Poisonings 1.12 1.03 – 1.23 0.0104 522 5213 all phecode
819
Skull and face fracture and other intercranial
Skull and face fracture and other intercranial injury
 Injuries & Poisonings 1.02 0.982 – 1.06 0.323 2957 29596 all phecode
823 Torus fracture Injuries & Poisonings 0.999 0.951 – 1.05 0.984 1673 16710 all phecode
830 Dislocation Injuries & Poisonings 1.03 0.983 – 1.08 0.224 2088 20872 all phecode
835 Internal derangement of knee Injuries & Poisonings 1.02 1.01 – 1.04 0.00411 15221 152247 all phecode
836 Traumatic arthropathy Injuries & Poisonings 1.05 0.957 – 1.14 0.324 526 5267 all phecode
840 Sprains and strains Injuries & Poisonings 0.941 0.856 – 1.03 0.209 470 4697 all phecode
850 Hemorrhage or hematoma complicating a procedure Injuries & Poisonings 1.05 1.02 – 1.08 0.000651 5259 52626 all phecode
851
Complications of transplants and reattached
Complications of transplants and reattached limbs
 Injuries & Poisonings 1.19 1.02 – 1.4 0.0319 157 1567 all phecode
853 Complication of colostomy or enterostomy Injuries & Poisonings 1.1 1 – 1.2 0.0423 501 5010 all phecode
854
Complications of cardiac/vascular device
Complications of cardiac/vascular device, implant, and graft
 Injuries & Poisonings 1.07 1.02 – 1.12 0.00621 1826 18238 all phecode
857
Mechanical complication of unspecified
Mechanical complication of unspecified genitourinary device, implant, and graft
 Injuries & Poisonings 1.04 0.978 – 1.1 0.233 1241 12418 all phecode
858 Complication of internal orthopedic device Injuries & Poisonings 1.02 0.987 – 1.06 0.201 3158 31607 all phecode
859
Complication due to other implant and internal
Complication due to other implant and internal device
 Injuries & Poisonings 1.01 0.975 – 1.05 0.56 3259 32599 all phecode
860 Bone marrow or stem cell transplant Neoplasms 1.22 0.955 – 1.55 0.112 68 680 all phecode
870 Open wounds of head; neck; and trunk Injuries & Poisonings 1.01 0.98 – 1.05 0.415 3502 35062 all phecode
870.1 Open wound or laceration of eye or eyelid Injuries & Poisonings 1.01 0.887 – 1.14 0.915 272 2713 all phecode
870.2 Open wound of ear Injuries & Poisonings 1.1 0.946 – 1.27 0.223 196 1949 all phecode
870.3 Other open wound of head and face Injuries & Poisonings 1 0.964 – 1.04 0.954 2904 29085 all phecode
870.4 Open wound of nose and sinus Injuries & Poisonings 0.973 0.845 – 1.12 0.708 220 2199 all phecode
870.6 Open wound of neck Injuries & Poisonings 1 0.791 – 1.28 0.969 68 678 all phecode
871 Open wounds of extremities Injuries & Poisonings 0.999 0.967 – 1.03 0.946 4063 40648 all phecode
871.1 Open wound of hand except finger(s) Injuries & Poisonings 1.18 0.877 – 1.58 0.28 53 530 all phecode
871.2 Open wound of finger(s) Injuries & Poisonings 0.959 0.773 – 1.19 0.7 91 900 all phecode
871.3 Open wound of foot except toe(s) alone Injuries & Poisonings 0.973 0.836 – 1.13 0.717 178 1785 all phecode
872 Traumatic amputation Injuries & Poisonings 0.924 0.84 – 1.02 0.101 475 4742 all phecode
873 Broken tooth Injuries & Poisonings 0.908 0.795 – 1.04 0.158 229 2289 all phecode
874 Complication of amputation stump Injuries & Poisonings 1.18 1 – 1.38 0.0439 169 1710 all phecode
905
Late effects of musculoskeletal and connective
Late effects of musculoskeletal and connective tissue injuries
 Injuries & Poisonings 0.901 0.764 – 1.06 0.214 157 1567 all phecode
907 Injuries to the nervous system Injuries & Poisonings 1.03 0.974 – 1.09 0.304 1314 13140 all phecode
915 Superficial injury without mention of infection Injuries & Poisonings 1.03 0.995 – 1.06 0.105 4260 42663 all phecode
916 Contusion Injuries & Poisonings 1.04 0.982 – 1.09 0.188 1450 14506 all phecode
930 Allergic reaction to food Injuries & Poisonings 0.961 0.825 – 1.12 0.612 179 1807 all phecode
938 Dermatitis due to solar radiation Injuries & Poisonings 0.984 0.886 – 1.09 0.756 389 3899 all phecode
938.2 Chronic dermatitis due to solar radiation Injuries & Poisonings 0.951 0.835 – 1.08 0.456 252 2530 all phecode
939
Atopic/contact dermatitis due to other or
Atopic/contact dermatitis due to other or unspecified
 Dermatologic 0.976 0.933 – 1.02 0.289 2094 20961 all phecode
941 Adverse reaction to serum or vaccine Injuries & Poisonings 0.904 0.789 – 1.04 0.148 225 2249 all phecode
942 Infusion and transfusion reaction Injuries & Poisonings 1.26 1.04 – 1.54 0.021 104 1038 all phecode
946 Anaphylactic shock NOS Injuries & Poisonings 1.01 0.929 – 1.11 0.755 550 5509 all phecode
947 Urticaria Injuries & Poisonings 1.01 0.905 – 1.12 0.912 371 3707 all phecode
949 Allergies, other Injuries & Poisonings 1.12 1.01 – 1.24 0.0308 397 3989 all phecode
952
Spinal cord injury without evidence of spinal
Spinal cord injury without evidence of spinal bone injury
 Injuries & Poisonings 0.948 0.858 – 1.05 0.288 423 4224 all phecode
957 Injury to other and unspecified nerves Injuries & Poisonings 1.24 1.1 – 1.41 0.000567 269 2698 all phecode
958
Certain early complications of trauma or
Certain early complications of trauma or procedure
 Injuries & Poisonings 0.993 0.906 – 1.09 0.886 491 4926 all phecode
958.1 Postoperative shock Injuries & Poisonings 1.41 1.06 – 1.87 0.0171 55 555 all phecode
958.2 Traumatic and surgical subcutaneous emphysema Injuries & Poisonings 0.88 0.697 – 1.11 0.279 74 740 all phecode
960 Poisoning by antibiotics Injuries & Poisonings 1.04 1.03 – 1.06 8.82e-08 18100 181147 all phecode
960.2 Allergy/adverse effect of penicillin Injuries & Poisonings 1.03 1.02 – 1.05 4.52e-05 15846 158623 all phecode
961 Poisoning by other anti-infectives Injuries & Poisonings 1.13 1.02 – 1.25 0.016 420 4195 all phecode
961.1 Poisoning/allergy of sulfonamides Injuries & Poisonings 0.997 0.93 – 1.07 0.941 869 8703 all phecode
962 Poisoning by hormones and synthetic substitutes Injuries & Poisonings 1.02 0.915 – 1.13 0.745 371 3707 all phecode
962.3
Hormones and synthetic substitutes causing
Hormones and synthetic substitutes causing adverse effects in therapeutic use
 Injuries & Poisonings 1.02 0.919 – 1.14 0.673 364 3638 all phecode
963 Poisoning by primarily systemic agents Injuries & Poisonings 1.02 0.892 – 1.17 0.755 223 2228 all phecode
964
Poisoning by agents primarily affecting blood
Poisoning by agents primarily affecting blood constituents
 Injuries & Poisonings 0.977 0.866 – 1.1 0.702 282 2830 all phecode
964.1 Anticoagulants causing adverse effects Injuries & Poisonings 0.971 0.858 – 1.1 0.641 276 2770 all phecode
965
Poisoning by analgesics, antipyretics, and
Poisoning by analgesics, antipyretics, and antirheumatics
 Injuries & Poisonings 1.06 1.03 – 1.09 7.32e-06 6082 60875 all phecode
965.1
Opiates and related narcotics causing adverse
Opiates and related narcotics causing adverse effects in therapeutic use
 Injuries & Poisonings 1.07 1.01 – 1.14 0.0235 1144 11447 all phecode
965.2
Antirheumatics causing adverse effects in
Antirheumatics causing adverse effects in therapeutic use
 Injuries & Poisonings 1.1 1 – 1.2 0.0502 476 4767 all phecode
965.3
Salicylates causing adverse effects in
Salicylates causing adverse effects in therapeutic use
 Injuries & Poisonings 1.08 0.978 – 1.2 0.123 403 4045 all phecode
966
Poisoning by anticonvulsants and
Poisoning by anticonvulsants and anti-Parkinsonism drugs
 Injuries & Poisonings 1.04 0.951 – 1.14 0.384 512 5123 all phecode
967
Adverse effects of sedatives or other central
Adverse effects of sedatives or other central nervous system depressants and anesthetics
 Injuries & Poisonings 1.06 0.973 – 1.15 0.187 583 5843 all phecode
969 Poisoning by psychotropic agents Injuries & Poisonings 1.05 0.999 – 1.1 0.0541 1950 19519 all phecode
971
Poisoning by drugs primarily affecting the
Poisoning by drugs primarily affecting the autonomic nervous system
 Injuries & Poisonings 0.891 0.767 – 1.04 0.132 190 1908 all phecode
972
Poisoning by agents primarily affecting the
Poisoning by agents primarily affecting the cardiovascular system
 Injuries & Poisonings 1.07 0.947 – 1.22 0.269 271 2717 all phecode
972.6 Antihypertensive agents causing adverse effects Injuries & Poisonings 0.922 0.744 – 1.14 0.461 84 849 all phecode
973
Poisoning by agents primarily affecting the
Poisoning by agents primarily affecting the gastrointestinal system
 Injuries & Poisonings 0.941 0.772 – 1.15 0.55 108 1080 all phecode
974
Poisoning by water, mineral, and uric acid
Poisoning by water, mineral, and uric acid metabolism drugs
 Injuries & Poisonings 0.995 0.816 – 1.21 0.958 101 1018 all phecode
975
Poisoning by agents primarily acting on the
Poisoning by agents primarily acting on the smooth and skeletal muscles and respiratory system
 Injuries & Poisonings 1.06 0.824 – 1.36 0.647 64 640 all phecode
976
Poisoning by agents primarily affecting skin &
Poisoning by agents primarily affecting skin & mucous membrane, ophthalmological, otorhinolaryngological, & dental drugs
 Injuries & Poisonings 0.873 0.67 – 1.14 0.311 58 580 all phecode
977 Personal history of allergy to medicinal agents Injuries & Poisonings 1.04 0.906 – 1.19 0.598 234 2337 all phecode
979 Adverse drug events and drug allergies Injuries & Poisonings 1.06 0.98 – 1.14 0.145 698 6966 all phecode
981
Toxic effect of (non-ethyl) alcohol and
Toxic effect of (non-ethyl) alcohol and petroleum and other solvents
 Injuries & Poisonings 1.02 0.884 – 1.18 0.775 200 1999 all phecode
986 Toxic effect of carbon monoxide Injuries & Poisonings 1.07 0.837 – 1.37 0.581 62 620 all phecode
987 Toxic effect of other gases, fumes, or vapors Injuries & Poisonings 1.11 0.91 – 1.36 0.301 105 1049 all phecode
988 Toxic effect of noxious substances eaten as food Injuries & Poisonings 0.928 0.765 – 1.12 0.445 111 1128 all phecode
989
Toxic effect of other substances, chiefly
Toxic effect of other substances, chiefly nonmedicinal as to source
 Injuries & Poisonings 0.988 0.798 – 1.22 0.91 89 890 all phecode
990 Effects radiation NOS Injuries & Poisonings 1.05 1.02 – 1.09 0.00491 3113 31140 all phecode
994 Sepsis and SIRS Injuries & Poisonings 1.05 1.01 – 1.09 0.0147 3028 30268 all phecode
994.2 Sepsis Injuries & Poisonings 1.05 1.01 – 1.09 0.0147 3028 30268 all phecode
008 Intestinal infection Infectious Diseases 1.01 0.982 – 1.03 0.664 7801 83500 exclusion phecode
008.5 Bacterial enteritis Infectious Diseases 1.01 0.964 – 1.05 0.81 2432 25627 exclusion phecode
008.52 Intestinal infection due to C. difficile Infectious Diseases 0.964 0.886 – 1.05 0.396 575 6126 exclusion phecode
008.6 Viral Enteritis Infectious Diseases 0.999 0.926 – 1.08 0.97 743 8128 exclusion phecode
008.7 Intestinal infection due to protozoa Infectious Diseases 1.03 0.781 – 1.36 0.829 53 526 exclusion phecode
010 Tuberculosis Infectious Diseases 0.872 0.741 – 1.03 0.102 154 1538 exclusion phecode
038 Septicemia Infectious Diseases 1.02 0.982 – 1.05 0.358 3616 39127 exclusion phecode
038.1 Gram negative septicemia Infectious Diseases 0.99 0.919 – 1.07 0.8 733 7938 exclusion phecode
038.2 Gram positive septicemia Infectious Diseases 0.945 0.854 – 1.05 0.275 413 4672 exclusion phecode
041 Bacterial infection NOS Infectious Diseases 1.02 0.997 – 1.04 0.0914 10505 113294 exclusion phecode
041.1 Staphylococcus infections Infectious Diseases 1.03 0.989 – 1.07 0.163 2641 29478 exclusion phecode
041.2 Streptococcus infection Infectious Diseases 1 0.949 – 1.06 0.951 1436 15459 exclusion phecode
041.4 E. coli Infectious Diseases 1 0.963 – 1.05 0.83 2350 25798 exclusion phecode
053 Herpes zoster Infectious Diseases 1.06 0.951 – 1.18 0.301 370 3849 exclusion phecode
053.1 Herpes zoster with nervous system complications Infectious Diseases 1.16 0.929 – 1.45 0.189 87 886 exclusion phecode
054 Herpes simplex Infectious Diseases 0.983 0.852 – 1.13 0.815 200 1993 exclusion phecode
070 Viral hepatitis Infectious Diseases 1.03 0.94 – 1.12 0.562 527 5587 exclusion phecode
070.1 Viral hepatitis A Infectious Diseases 0.918 0.712 – 1.18 0.511 63 653 exclusion phecode
070.2 Viral hepatitis B Infectious Diseases 1.1 0.912 – 1.32 0.321 118 1254 exclusion phecode
070.3 Viral hepatitis C Infectious Diseases 1.03 0.904 – 1.17 0.657 234 2444 exclusion phecode
070.4 Chronic hepatitis Infectious Diseases 1.03 0.905 – 1.17 0.662 243 2621 exclusion phecode
070.9 Hepatitis NOS Infectious Diseases 1.05 0.933 – 1.17 0.447 317 4032 exclusion phecode
071 Human immunodeficiency virus [HIV] disease Infectious Diseases 0.879 0.738 – 1.05 0.147 137 1384 exclusion phecode
071.1 HIV infection, symptomatic Infectious Diseases 0.826 0.676 – 1.01 0.0593 107 1090 exclusion phecode
078 Viral warts & HPV Infectious Diseases 1.09 1.02 – 1.17 0.00819 927 9515 exclusion phecode
079 Viral infection Infectious Diseases 1.01 0.968 – 1.05 0.704 2526 26371 exclusion phecode
079.1 Varicella infection Infectious Diseases 1.06 0.825 – 1.36 0.652 61 613 exclusion phecode
080 Postoperative infection Infectious Diseases 1.01 0.973 – 1.04 0.764 3928 42268 exclusion phecode
081
Infection/inflammation of internal prosthetic
Infection/inflammation of internal prosthetic device; implant; and graft
 Infectious Diseases 1.03 0.985 – 1.08 0.192 2215 23313 exclusion phecode
090
Sexually transmitted infections (not HIV or
Sexually transmitted infections (not HIV or hepatitis)
 Infectious Diseases 0.992 0.76 – 1.3 0.955 60 662 exclusion phecode
1000 Burns Injuries & Poisonings 1.04 0.953 – 1.14 0.369 527 5463 exclusion phecode
1001 Foreign body injury Injuries & Poisonings 0.993 0.934 – 1.06 0.816 1110 11318 exclusion phecode
1002
Symptoms concerning nutrition, metabolism, and
Symptoms concerning nutrition, metabolism, and development
 Injuries & Poisonings 1 0.972 – 1.03 0.954 4996 51572 exclusion phecode
1004
Other signs and symptoms involving emotional
Other signs and symptoms involving emotional state
 Injuries & Poisonings 0.872 0.769 – 0.989 0.0325 265 2835 exclusion phecode
1005 Other symptoms Injuries & Poisonings 0.97 0.916 – 1.03 0.303 1294 13556 exclusion phecode
1006 Crushing injury Injuries & Poisonings 0.928 0.815 – 1.06 0.26 237 2403 exclusion phecode
1007 Injury to blood vessels Injuries & Poisonings 1.02 0.896 – 1.17 0.744 236 2392 exclusion phecode
1008 Crushing or internal injury to organs Injuries & Poisonings 1.03 0.962 – 1.1 0.412 944 9490 exclusion phecode
1009 Injury, NOS Injuries & Poisonings 1 0.977 – 1.02 0.986 7818 80029 exclusion phecode
1010 Other tests Injuries & Poisonings 1.02 0.993 – 1.05 0.149 5217 55996 exclusion phecode
1011 Complications of surgical and medical procedures Injuries & Poisonings 1.02 0.995 – 1.04 0.131 8339 85978 exclusion phecode
1012 Late effect Injuries & Poisonings 1.12 0.914 – 1.38 0.269 95 998 exclusion phecode
1013 Asphyxia and hypoxemia Injuries & Poisonings 1.01 0.892 – 1.14 0.902 283 2995 exclusion phecode
1014 Effects of heat, cold and air pressure Injuries & Poisonings 0.924 0.719 – 1.19 0.535 62 622 exclusion phecode
1015 Effects of other external causes Injuries & Poisonings 1.01 0.976 – 1.04 0.607 3770 40032 exclusion phecode
1019
Other ill-defined and unknown causes of
Other ill-defined and unknown causes of morbidity and mortality
 Injuries & Poisonings 1.02 1 – 1.04 0.0114 14592 150541 exclusion phecode
110 Dermatophytosis / Dermatomycosis Infectious Diseases 1.08 0.946 – 1.23 0.262 252 2617 exclusion phecode
110.1 Dermatophytosis Infectious Diseases 1.08 0.943 – 1.23 0.277 247 2562 exclusion phecode
110.11 Dermatophytosis of nail Infectious Diseases 1.13 0.895 – 1.43 0.3 72 708 exclusion phecode
110.12 Althete's foot Infectious Diseases 0.972 0.808 – 1.17 0.758 126 1320 exclusion phecode
112 Candidiasis Infectious Diseases 1.01 0.965 – 1.06 0.624 1898 19991 exclusion phecode
117 Mycoses Infectious Diseases 1.03 0.902 – 1.17 0.697 248 2530 exclusion phecode
117.4 Aspergillosis Infectious Diseases 0.968 0.821 – 1.14 0.703 151 1525 exclusion phecode
130 Spirochetal infection Infectious Diseases 0.913 0.724 – 1.15 0.44 79 764 exclusion phecode
133 Arthropod-borne diseases Infectious Diseases 1.18 0.905 – 1.55 0.217 64 644 exclusion phecode
134 Helminthiases Infectious Diseases 0.985 0.818 – 1.19 0.877 119 1222 exclusion phecode
134.1 Intestinal helminthiases Infectious Diseases 1.02 0.835 – 1.25 0.842 99 1022 exclusion phecode
136 Other infectious and parasitic diseases Infectious Diseases 1.11 0.957 – 1.28 0.169 189 1924 exclusion phecode
145 Cancer of mouth Neoplasms 1.09 1.01 – 1.19 0.0361 608 5992 exclusion phecode
145.2 Cancer of tongue Neoplasms 1.11 0.986 – 1.25 0.0838 292 2888 exclusion phecode
145.3 Cancer of major salivary glands Neoplasms 1 0.819 – 1.22 0.996 104 996 exclusion phecode
145.5 Cancer of the mouth floor Neoplasms 0.911 0.68 – 1.22 0.529 49 502 exclusion phecode
149 Cancer of larynx, pharynx, nasal cavities Neoplasms 1.07 0.982 – 1.16 0.126 572 5872 exclusion phecode
149.1 Cancer of oropharynx Neoplasms 1.04 0.908 – 1.19 0.584 229 2341 exclusion phecode
149.4 Cancer of larynx Neoplasms 1.09 0.951 – 1.25 0.215 231 2424 exclusion phecode
149.9 Cancer of of nasal cavities Neoplasms 1.02 0.776 – 1.33 0.902 55 543 exclusion phecode
150 Cancer of esophagus Neoplasms 0.936 0.865 – 1.01 0.0969 676 7038 exclusion phecode
151 Cancer of stomach Neoplasms 0.986 0.9 – 1.08 0.756 504 5252 exclusion phecode
153 Colorectal cancer Neoplasms 1 0.971 – 1.03 0.881 4216 42788 exclusion phecode
153.2 Colon cancer Neoplasms 0.991 0.954 – 1.03 0.653 2858 28989 exclusion phecode
153.3
Malignant neoplasm of rectum, rectosigmoid
Malignant neoplasm of rectum, rectosigmoid junction, and anus
 Neoplasms 1.01 0.966 – 1.06 0.614 1984 20217 exclusion phecode
155 Cancer of liver and intrahepatic bile duct Neoplasms 1.01 0.905 – 1.14 0.81 327 3715 exclusion phecode
155.1 Malignant neoplasm of liver, primary Neoplasms 1.07 0.888 – 1.3 0.459 114 1454 exclusion phecode
157 Pancreatic cancer Neoplasms 1.09 1 – 1.18 0.0466 576 6096 exclusion phecode
158
Neoplasm of unspecified nature of digestive
Neoplasm of unspecified nature of digestive system
 Neoplasms 0.967 0.905 – 1.03 0.314 967 9951 exclusion phecode
159
Malignant neoplasm of other and ill-defined
Malignant neoplasm of other and ill-defined sites within the digestive organs and peritoneum
 Neoplasms 1 0.972 – 1.03 0.95 5079 51987 exclusion phecode
159.2
Malignant neoplasm of small intestine
Malignant neoplasm of small intestine, including duodenum
 Neoplasms 1.03 0.885 – 1.21 0.67 172 1773 exclusion phecode
159.3
Malignant neoplasm of gallbladder and
Malignant neoplasm of gallbladder and extrahepatic bile ducts
 Neoplasms 1.02 0.877 – 1.19 0.77 183 1911 exclusion phecode
159.4
Malignant neoplasm of retroperitoneum and
Malignant neoplasm of retroperitoneum and peritoneum
 Neoplasms 1.05 0.898 – 1.23 0.54 177 1800 exclusion phecode
164 Cancer of intrathoracic organs Neoplasms 1.33 1.01 – 1.75 0.0401 56 562 exclusion phecode
165 Cancer within the respiratory system Neoplasms 1.03 0.988 – 1.07 0.168 2559 26211 exclusion phecode
165.1 Cancer of bronchus; lung Neoplasms 1.01 0.966 – 1.06 0.649 2019 20736 exclusion phecode
170 Cancer of bone and connective tissue Neoplasms 1.07 0.967 – 1.18 0.19 407 4098 exclusion phecode
170.1 Bone cancer Neoplasms 1.16 0.971 – 1.39 0.101 123 1237 exclusion phecode
170.2 Cancer of connective tissue Neoplasms 1.06 0.938 – 1.19 0.369 308 3112 exclusion phecode
172 Skin cancer Neoplasms 0.985 0.967 – 1 0.112 12674 126217 exclusion phecode
172.1 Melanomas of skin, dx or hx Neoplasms 0.968 0.929 – 1.01 0.113 2538 25249 exclusion phecode
172.11 Melanomas of skin Neoplasms 0.97 0.931 – 1.01 0.136 2568 25565 exclusion phecode
172.2 Other non-epithelial cancer of skin Neoplasms 0.985 0.965 – 1.01 0.145 10324 102723 exclusion phecode
172.3 Carcinoma in situ of skin Neoplasms 1.01 0.926 – 1.09 0.898 617 6227 exclusion phecode
173 Neoplasm of uncertain behavior of skin Neoplasms 0.911 0.779 – 1.06 0.241 169 1726 exclusion phecode
174 Breast cancer Neoplasms 1.01 0.99 – 1.03 0.366 12089 121554 exclusion phecode
174.1 Breast cancer [female] Neoplasms 1.01 0.99 – 1.03 0.346 11895 119587 exclusion phecode
174.11 Malignant neoplasm of female breast Neoplasms 1.01 0.992 – 1.03 0.238 11201 112851 exclusion phecode
174.3 Neoplasm of uncertain behavior of breast Neoplasms 1.09 0.892 – 1.33 0.405 109 1103 exclusion phecode
175 Acquired absence of breast Neoplasms 0.983 0.941 – 1.03 0.44 2267 23059 exclusion phecode
180 Cervical cancer and dysplasia Neoplasms 0.975 0.933 – 1.02 0.273 2101 21052 exclusion phecode
180.1 Cervical cancer Neoplasms 0.968 0.854 – 1.1 0.607 263 2628 exclusion phecode
180.3
Cervical intraepithelial neoplasia [CIN]
Cervical intraepithelial neoplasia [CIN] [Cervical dysplasia]
 Neoplasms 0.98 0.936 – 1.03 0.385 2006 20110 exclusion phecode
182 Malignant neoplasm of uterus Neoplasms 0.984 0.927 – 1.04 0.593 1172 12252 exclusion phecode
184 Cancer of other female genital organs Neoplasms 1.05 0.992 – 1.11 0.0936 1317 13206 exclusion phecode
184.1
Malignant neoplasm of ovary and other uterine
Malignant neoplasm of ovary and other uterine adnexa
 Neoplasms 1.04 0.975 – 1.12 0.224 926 9253 exclusion phecode
184.11 Malignant neoplasm of ovary Neoplasms 1.06 0.989 – 1.13 0.102 899 8989 exclusion phecode
184.2
Cancer of other female genital organs
Cancer of other female genital organs (excluding uterus and ovary)
 Neoplasms 1.02 0.903 – 1.15 0.761 292 2931 exclusion phecode
185 Cancer of prostate Neoplasms 1.02 0.989 – 1.05 0.23 5561 53416 exclusion phecode
187 Cancer of other male genital organs Neoplasms 0.97 0.876 – 1.08 0.565 409 4176 exclusion phecode
187.1
Malignant neoplasm of unspecified male genital
Malignant neoplasm of unspecified male genital organ
 Neoplasms 0.879 0.677 – 1.14 0.334 61 652 exclusion phecode
187.2 Malignant neoplasm of testis Neoplasms 0.975 0.858 – 1.11 0.705 262 2693 exclusion phecode
187.8
Neoplasm of uncertain behavior of male genital
Neoplasm of uncertain behavior of male genital organs
 Neoplasms 1.03 0.834 – 1.26 0.807 101 1018 exclusion phecode
189
Cancer of urinary organs (incl. kidney and
Cancer of urinary organs (incl. kidney and bladder)
 Neoplasms 1.03 0.996 – 1.07 0.0849 3716 38439 exclusion phecode
189.1 Cancer of kidney and renal pelvis Neoplasms 1.04 0.974 – 1.11 0.235 964 10024 exclusion phecode
189.11 Malignant neoplasm of kidney, except pelvis Neoplasms 1.05 0.985 – 1.13 0.13 924 9659 exclusion phecode
189.12 Malignant neoplasm of renal pelvis Neoplasms 0.879 0.675 – 1.14 0.336 62 608 exclusion phecode
189.2 Cancer of bladder Neoplasms 1.04 0.998 – 1.09 0.0624 2133 22199 exclusion phecode
189.21 Malignant neoplasm of bladder Neoplasms 1.05 0.999 – 1.1 0.0577 1895 19748 exclusion phecode
189.4 Malignant neoplasm of other urinary organs Neoplasms 0.799 0.664 – 0.963 0.0183 134 1315 exclusion phecode
190 Cancer of eye Neoplasms 0.961 0.818 – 1.13 0.632 161 1637 exclusion phecode
191
Manlignant and unknown neoplasms of brain and
Manlignant and unknown neoplasms of brain and nervous system
 Neoplasms 0.99 0.914 – 1.07 0.803 649 6455 exclusion phecode
191.1 Cancer of brain and nervous system Neoplasms 1 0.917 – 1.09 0.971 536 5303 exclusion phecode
191.11 Cancer of brain Neoplasms 1 0.914 – 1.1 0.964 498 4914 exclusion phecode
193 Thyroid cancer Neoplasms 1.04 0.93 – 1.17 0.473 320 3328 exclusion phecode
194 Cancer of other endocrine glands Neoplasms 0.888 0.709 – 1.11 0.301 81 896 exclusion phecode
195 Cancer, suspected or other Neoplasms 1.02 1 – 1.04 0.0132 15717 155208 exclusion phecode
195.1 Malignant neoplasm, other Neoplasms 1.02 1 – 1.04 0.0318 15068 149539 exclusion phecode
197 Chemotherapy Neoplasms 1.02 1.01 – 1.04 0.00166 19777 201681 exclusion phecode
198 Secondary malignant neoplasm Neoplasms 1.02 0.995 – 1.04 0.139 8818 89754 exclusion phecode
198.1 Secondary malignancy of lymph nodes Neoplasms 1 0.976 – 1.03 0.753 4996 50682 exclusion phecode
198.2 Secondary malignancy of respiratory organs Neoplasms 0.998 0.954 – 1.04 0.937 2085 21259 exclusion phecode
198.3
Secondary malignant neoplasm of digestive
Secondary malignant neoplasm of digestive systems
 Neoplasms 0.967 0.916 – 1.02 0.221 1433 14603 exclusion phecode
198.4 Secondary malignant neoplasm of liver Neoplasms 1.01 0.971 – 1.05 0.582 2439 24960 exclusion phecode
198.5 Secondary malignancy of brain/spine Neoplasms 1.02 0.947 – 1.1 0.608 798 7968 exclusion phecode
198.6 Secondary malignancy of bone Neoplasms 1.07 1.02 – 1.12 0.0065 1979 20192 exclusion phecode
198.7 Secondary malignant neoplasm of skin Neoplasms 0.953 0.817 – 1.11 0.545 174 1775 exclusion phecode
199 Neoplasm of uncertain behavior Neoplasms 1.01 0.953 – 1.07 0.752 1319 13484 exclusion phecode
199.4 Neurofibromatosis Neoplasms 0.906 0.732 – 1.12 0.366 91 905 exclusion phecode
200 Myeloproliferative disease Neoplasms 1.04 0.975 – 1.12 0.214 889 9257 exclusion phecode
200.1 Polycythemia vera Neoplasms 1 0.897 – 1.12 0.954 331 3575 exclusion phecode
201 Hodgkin's disease Neoplasms 0.877 0.765 – 1 0.0584 240 2447 exclusion phecode
202 Cancer of other lymphoid, histiocytic tissue Neoplasms 0.982 0.939 – 1.03 0.422 2095 21255 exclusion phecode
202.2 Non-Hodgkins lymphoma Neoplasms 0.978 0.931 – 1.03 0.392 1669 16881 exclusion phecode
202.21 Nodular lymphoma Neoplasms 0.942 0.843 – 1.05 0.287 340 3414 exclusion phecode
202.24 Large cell lymphoma Neoplasms 1.02 0.937 – 1.12 0.598 538 5448 exclusion phecode
204 Leukemia Neoplasms 1.02 0.973 – 1.08 0.358 1528 15471 exclusion phecode
204.1 Lymphoid leukemia Neoplasms 1.01 0.925 – 1.1 0.814 521 5374 exclusion phecode
204.11 Lymphoid leukemia, acute Neoplasms 1.12 0.831 – 1.5 0.467 52 529 exclusion phecode
204.12 Lymphoid leukemia, chronic Neoplasms 1.01 0.918 – 1.11 0.858 453 4700 exclusion phecode
204.2 Myeloid leukemia Neoplasms 1.02 0.919 – 1.12 0.764 436 4302 exclusion phecode
204.21 Myeloid leukemia, acute Neoplasms 0.989 0.88 – 1.11 0.851 311 3041 exclusion phecode
204.22 Myeloid leukemia, chronic Neoplasms 1.05 0.873 – 1.25 0.63 137 1359 exclusion phecode
204.4 Multiple myeloma Neoplasms 0.998 0.913 – 1.09 0.967 517 5179 exclusion phecode
208 Benign neoplasm of colon Neoplasms 1.02 1 – 1.04 0.0149 18008 180018 exclusion phecode
210 Benign neoplasm of lip, oral cavity, and pharynx Neoplasms 1.01 0.945 – 1.08 0.737 901 9212 exclusion phecode
211
Benign neoplasm of other parts of digestive
Benign neoplasm of other parts of digestive system
 Neoplasms 1.05 1.02 – 1.08 0.00238 4765 49410 exclusion phecode
212
Benign neoplasm of respiratory and
Benign neoplasm of respiratory and intrathoracic organs
 Neoplasms 1.02 0.909 – 1.14 0.768 319 3256 exclusion phecode
213 Benign neoplasm of bone and articular cartilage Neoplasms 0.924 0.82 – 1.04 0.192 304 3023 exclusion phecode
214 Lipoma Neoplasms 1.02 0.996 – 1.05 0.0895 5824 58607 exclusion phecode
214.1 Lipoma of skin and subcutaneous tissue Neoplasms 1.04 1.01 – 1.07 0.014 4307 43303 exclusion phecode
215
Other benign neoplasm of connective and other
Other benign neoplasm of connective and other soft tissue
 Neoplasms 0.986 0.926 – 1.05 0.649 1055 10460 exclusion phecode
216 Benign neoplasm of skin Neoplasms 0.986 0.963 – 1.01 0.253 7257 72741 exclusion phecode
217 Vascular hamartomas and non-neoplastic nevi Neoplasms 1.02 0.937 – 1.11 0.634 587 5954 exclusion phecode
217.1 Nevus, non-neoplastic Neoplasms 1.01 0.927 – 1.1 0.793 551 5598 exclusion phecode
218 Benign neoplasm of uterus Neoplasms 1.02 1 – 1.04 0.0464 9606 96769 exclusion phecode
218.1 Uterine leiomyoma Neoplasms 1.02 1 – 1.04 0.0463 9813 98814 exclusion phecode
218.2 Other benign neoplasm of uterus Neoplasms 1 0.896 – 1.12 0.965 336 3427 exclusion phecode
220 Benign neoplasm of ovary Neoplasms 1.03 0.977 – 1.09 0.25 1358 13942 exclusion phecode
221 Benign neoplasm of other female genital organs Neoplasms 1.03 0.891 – 1.2 0.668 200 2113 exclusion phecode
222 Benign neoplasm of male genital organs Neoplasms 0.936 0.788 – 1.11 0.449 148 1462 exclusion phecode
223
Benign neoplasm of kidney and other urinary
Benign neoplasm of kidney and other urinary organs
 Neoplasms 1.04 0.882 – 1.22 0.666 156 1600 exclusion phecode
224 Benign neoplasm of eye Neoplasms 1.02 0.837 – 1.23 0.878 114 1213 exclusion phecode
224.1 Benign neoplasm of eye, uveal Neoplasms 1.09 0.83 – 1.43 0.543 56 632 exclusion phecode
225
Benign neoplasm of brain and other parts of
Benign neoplasm of brain and other parts of nervous system
 Neoplasms 1.02 0.951 – 1.1 0.52 765 7697 exclusion phecode
225.1
Benign neoplasm of brain, cranial nerves
Benign neoplasm of brain, cranial nerves, meninges
 Neoplasms 1.02 0.94 – 1.1 0.693 726 7322 exclusion phecode
225.2 Benign neoplasm of spinal cord, meninges Neoplasms 0.99 0.755 – 1.3 0.942 55 565 exclusion phecode
226 Benign neoplasm of thyroid glands Neoplasms 1.02 0.899 – 1.17 0.723 251 2537 exclusion phecode
227
Benign neoplasm of other endocrine glands and
Benign neoplasm of other endocrine glands and related structures
 Neoplasms 1.02 0.95 – 1.1 0.533 757 8145 exclusion phecode
227.1 Benign neoplasm of adrenal gland Neoplasms 1.12 0.946 – 1.32 0.195 153 1741 exclusion phecode
227.2 Benign neoplasm of parathyroid gland Neoplasms 0.972 0.868 – 1.09 0.629 338 3497 exclusion phecode
227.3
Benign neoplasm of pituitary gland and
Benign neoplasm of pituitary gland and craniopharyngeal duct (pouch)
 Neoplasms 1.06 0.934 – 1.19 0.386 272 2944 exclusion phecode
228 Hemangioma and lymphangioma, any site Neoplasms 0.985 0.935 – 1.04 0.579 1494 15077 exclusion phecode
229 Benign neoplasm of unspecified sites Neoplasms 1.02 0.973 – 1.06 0.463 2281 22844 exclusion phecode
240 Simple and unspecified goiter Endocrine/metabolic 1.01 0.928 – 1.11 0.768 554 5744 exclusion phecode
241 Nontoxic nodular goiter Endocrine/metabolic 1.02 0.957 – 1.09 0.551 1055 10605 exclusion phecode
241.1 Nontoxic uninodular goiter Endocrine/metabolic 1.06 0.964 – 1.17 0.223 453 4518 exclusion phecode
241.2 Nontoxic multinodular goiter Endocrine/metabolic 0.984 0.907 – 1.07 0.691 641 6466 exclusion phecode
242 Thyrotoxicosis with or without goiter Endocrine/metabolic 1.07 1.02 – 1.13 0.00544 1673 17648 exclusion phecode
242.1 Graves' disease Endocrine/metabolic 1.05 0.948 – 1.16 0.363 418 4347 exclusion phecode
242.2 Toxic multinodular goiter Endocrine/metabolic 1.08 0.866 – 1.34 0.504 86 869 exclusion phecode
242.3 Exophthalmos Endocrine/metabolic 0.883 0.737 – 1.06 0.18 126 1301 exclusion phecode
244 Hypothyroidism Endocrine/metabolic 1.04 1.02 – 1.05 9.19e-05 13227 138345 exclusion phecode
244.1 Secondary hypothyroidism Endocrine/metabolic 1.03 0.968 – 1.1 0.325 1001 10545 exclusion phecode
244.2 Acquired hypothyroidism Endocrine/metabolic 0.945 0.759 – 1.18 0.61 87 957 exclusion phecode
244.4 Hypothyroidism NOS Endocrine/metabolic 1.04 1.02 – 1.06 8.76e-05 12609 132481 exclusion phecode
245 Thyroiditis Endocrine/metabolic 0.934 0.825 – 1.06 0.286 272 2761 exclusion phecode
245.2 Chronic thyroiditis Endocrine/metabolic 0.977 0.847 – 1.13 0.746 206 2085 exclusion phecode
245.21 Chronic lymphocytic thyroiditis Endocrine/metabolic 0.965 0.834 – 1.12 0.627 201 2015 exclusion phecode
246 Other disorders of thyroid Endocrine/metabolic 1.06 0.95 – 1.18 0.304 371 3790 exclusion phecode
250 Diabetes mellitus Endocrine/metabolic 1.32 1.29 – 1.36 6.35e-95 5756 181935 exclusion phecode
250.1 Type 1 diabetes Endocrine/metabolic 1.24 1.07 – 1.44 0.00394 172 27032 exclusion phecode
250.11 Type 1 diabetes with ketoacidosis Endocrine/metabolic 1.4 0.837 – 2.34 0.2 12 2342 exclusion phecode
250.12 Type 1 diabetes with renal manifestations Endocrine/metabolic 0.935 0.376 – 2.33 0.885 1 750 exclusion phecode
250.13 Type 1 diabetes with ophthalmic manifestations Endocrine/metabolic 1.37 0.732 – 2.58 0.324 6 4637 exclusion phecode
250.14 Type 1 diabetes with neurological manifestations Endocrine/metabolic 2.36 1.07 – 5.21 0.0338 3 1587 exclusion phecode
250.2 Type 2 diabetes Endocrine/metabolic 1.35 1.32 – 1.39 5.11e-96 4878 166402 exclusion phecode
250.21 Type 2 diabetes with ketoacidosis Endocrine/metabolic 0.913 0.552 – 1.51 0.721 12 1018 exclusion phecode
250.22 Type 2 diabetes with renal manifestations Endocrine/metabolic 0.655 0.39 – 1.1 0.111 10 1969 exclusion phecode
250.23 Type 2 diabetes with ophthalmic manifestations Endocrine/metabolic 1.64 1.24 – 2.16 0.00045 46 9635 exclusion phecode
250.24 Type 2 diabetes with neurological manifestations Endocrine/metabolic 1.63 1.1 – 2.42 0.0147 21 4949 exclusion phecode
250.4 Abnormal glucose Endocrine/metabolic 1.24 1.12 – 1.37 1.91e-05 423 6683 exclusion phecode
250.41 Impaired fasting glucose Endocrine/metabolic 1.29 1.11 – 1.5 0.000724 186 2598 exclusion phecode
250.42 Other abnormal glucose Endocrine/metabolic 1.22 1.07 – 1.39 0.0026 240 4099 exclusion phecode
250.5 Glycosuria or Acetonuria Endocrine/metabolic 1.31 1.06 – 1.61 0.0119 93 1287 exclusion phecode
250.6 Polyneuropathy in diabetes Endocrine/metabolic 1.43 0.897 – 2.27 0.134 14 3419 exclusion phecode
250.7 Diabetic retinopathy Endocrine/metabolic 1.17 0.941 – 1.47 0.156 76 12416 exclusion phecode
251.1 Hypoglycemia Endocrine/metabolic 1.12 0.991 – 1.26 0.0691 272 9153 exclusion phecode
252 Disorders of parathyroid gland Endocrine/metabolic 0.998 0.926 – 1.08 0.956 768 8265 exclusion phecode
252.1 Hyperparathyroidism Endocrine/metabolic 0.968 0.894 – 1.05 0.423 685 7393 exclusion phecode
252.2 Hypoparathyroidism Endocrine/metabolic 1.16 0.966 – 1.39 0.112 124 1345 exclusion phecode
253
Disorders of the pituitary gland and its
Disorders of the pituitary gland and its hypothalamic control
 Endocrine/metabolic 1.07 0.986 – 1.17 0.102 585 6425 exclusion phecode
253.1 Pituitary hyperfunction Endocrine/metabolic 1.05 0.895 – 1.24 0.539 162 1772 exclusion phecode
253.11 Acromegaly and gigantism Endocrine/metabolic 0.994 0.798 – 1.24 0.955 82 901 exclusion phecode
253.2 Pituitary hypofunction Endocrine/metabolic 1.06 0.92 – 1.21 0.441 216 2443 exclusion phecode
253.3 Diabetes insipidus Endocrine/metabolic 1.02 0.807 – 1.29 0.863 70 868 exclusion phecode
253.7 Other disorders of neurohypophysis Endocrine/metabolic 1 0.839 – 1.19 0.992 137 1477 exclusion phecode
255 Disorders of adrenal glands Endocrine/metabolic 1.04 0.957 – 1.14 0.337 539 6034 exclusion phecode
255.1 Adrenal hyperfunction Endocrine/metabolic 1.07 0.899 – 1.27 0.458 142 1704 exclusion phecode
255.11 Cushing's syndrome Endocrine/metabolic 0.961 0.767 – 1.2 0.727 79 984 exclusion phecode
255.12 Hyperaldosteronism Endocrine/metabolic 1.27 0.972 – 1.65 0.08 62 724 exclusion phecode
255.2 Adrenal hypofunction Endocrine/metabolic 1.01 0.902 – 1.13 0.846 310 3436 exclusion phecode
255.21 Glucocorticoid deficiency Endocrine/metabolic 1.01 0.904 – 1.14 0.821 309 3426 exclusion phecode
256 Ovarian dysfunction Endocrine/metabolic 1.08 0.942 – 1.24 0.264 223 2355 exclusion phecode
256.4 Polycystic ovaries Endocrine/metabolic 1.06 0.914 – 1.23 0.434 192 2054 exclusion phecode
257 Testicular dysfunction Endocrine/metabolic 1.15 0.958 – 1.37 0.136 134 1510 exclusion phecode
257.1 Testicular hypofunction Endocrine/metabolic 1.18 0.983 – 1.43 0.0758 125 1437 exclusion phecode
258 Iatrogenic endocrine disorders Endocrine/metabolic 1.01 0.81 – 1.26 0.918 80 958 exclusion phecode
259 Other endocrine disorders Endocrine/metabolic 0.984 0.823 – 1.18 0.864 133 1439 exclusion phecode
260 Protein-calorie malnutrition Endocrine/metabolic 1.1 0.947 – 1.27 0.221 185 1908 exclusion phecode
260.1 Cachexia Endocrine/metabolic 1.08 0.81 – 1.45 0.595 46 478 exclusion phecode
260.6 Anorexia Endocrine/metabolic 1 0.931 – 1.08 0.94 754 7811 exclusion phecode
261 Vitamin deficiency Endocrine/metabolic 1.03 0.967 – 1.1 0.35 1030 11349 exclusion phecode
261.2 Vitamin B-complex deficiencies Endocrine/metabolic 1 0.927 – 1.09 0.906 646 7125 exclusion phecode
261.4 Vitamin D deficiency Endocrine/metabolic 1.08 0.97 – 1.2 0.164 387 4256 exclusion phecode
261.41 Rickets or osteomalacia Endocrine/metabolic 1.13 0.89 – 1.42 0.323 71 738 exclusion phecode
262 Mineral deficiency NEC Endocrine/metabolic 0.904 0.786 – 1.04 0.155 216 2262 exclusion phecode
269 Proteinuria Endocrine/metabolic 1.11 0.983 – 1.25 0.0936 278 3150 exclusion phecode
270
Disorders of protein plasma/amino-acid
Disorders of protein plasma/amino-acid transport and metabolism
 Endocrine/metabolic 0.924 0.814 – 1.05 0.224 265 2832 exclusion phecode
270.3 Disorders of plasma protein metabolism Endocrine/metabolic 0.917 0.8 – 1.05 0.215 232 2426 exclusion phecode
270.32 Paraproteinemia Endocrine/metabolic 0.936 0.796 – 1.1 0.426 164 1769 exclusion phecode
270.33 Amyloidosis Endocrine/metabolic 1.07 0.882 – 1.31 0.477 104 1061 exclusion phecode
270.35 Macroglobulinemia Endocrine/metabolic 0.84 0.651 – 1.08 0.181 67 646 exclusion phecode
271
Disorders of carbohydrate transport and
Disorders of carbohydrate transport and metabolism
 Endocrine/metabolic 1.23 1.03 – 1.48 0.0226 130 1523 exclusion phecode
271.3
Intestinal disaccharidase deficiencies and
Intestinal disaccharidase deficiencies and disaccharide malabsorption
 Endocrine/metabolic 1.18 0.977 – 1.43 0.0863 116 1326 exclusion phecode
272 Disorders of lipoid metabolism Endocrine/metabolic 1.06 1.05 – 1.08 3.85e-22 28950 224168 exclusion phecode
272.1 Hyperlipidemia Endocrine/metabolic 1.06 1.05 – 1.08 2.05e-22 28885 223940 exclusion phecode
272.11 Hypercholesterolemia Endocrine/metabolic 1.06 1.05 – 1.08 9.21e-21 26890 217030 exclusion phecode
272.12 Hyperglyceridemia Endocrine/metabolic 1.27 0.954 – 1.68 0.102 47 554 exclusion phecode
272.13 Mixed hyperlipidemia Endocrine/metabolic 1.04 0.864 – 1.24 0.705 120 1555 exclusion phecode
272.9 Unspecified disorder of lipoid metabolism Endocrine/metabolic 0.981 0.836 – 1.15 0.82 161 1985 exclusion phecode
274 Gout and other crystal arthropathies Endocrine/metabolic 1.07 1.03 – 1.11 0.00039 3155 34506 exclusion phecode
274.1 Gout Endocrine/metabolic 1.06 1.02 – 1.11 0.00205 2649 29328 exclusion phecode
274.11 Gouty arthropathy Endocrine/metabolic 0.872 0.709 – 1.07 0.194 94 1039 exclusion phecode
274.2 Crystal arthropathies Endocrine/metabolic 1.08 0.987 – 1.18 0.0939 556 5758 exclusion phecode
274.21 Chondrocalcinosis Endocrine/metabolic 1.08 0.989 – 1.19 0.0853 513 5241 exclusion phecode
275 Disorders of mineral metabolism Endocrine/metabolic 0.994 0.947 – 1.04 0.79 1840 19677 exclusion phecode
275.1 Disorders of iron metabolism Hematopoietic 0.938 0.862 – 1.02 0.14 577 6082 exclusion phecode
275.3 Disorders of magnesium metabolism Endocrine/metabolic 1.08 0.967 – 1.22 0.167 308 3509 exclusion phecode
275.5 Disorders of calcium/phosphorus metabolism Endocrine/metabolic 1.01 0.946 – 1.07 0.828 1055 11243 exclusion phecode
275.53 Disorders of phosphorus metabolism Endocrine/metabolic 1.21 1.03 – 1.44 0.0241 151 1592 exclusion phecode
276
Disorders of fluid, electrolyte, and acid-base
Disorders of fluid, electrolyte, and acid-base balance
 Endocrine/metabolic 1.03 1 – 1.05 0.049 6025 68192 exclusion phecode
276.1 Electrolyte imbalance Endocrine/metabolic 1.02 0.985 – 1.06 0.253 3363 38240 exclusion phecode
276.11 Hyperosmolality and/or hypernatremia Endocrine/metabolic 1.06 0.911 – 1.23 0.45 186 2236 exclusion phecode
276.12 Hyposmolality and/or hyponatremia Endocrine/metabolic 1 0.951 – 1.05 0.953 1580 17053 exclusion phecode
276.13 Hyperpotassemia Endocrine/metabolic 1.04 0.959 – 1.13 0.352 644 9010 exclusion phecode
276.14 Hypopotassemia Endocrine/metabolic 1.01 0.951 – 1.07 0.791 1250 13379 exclusion phecode
276.4 Acid-base balance disorder Endocrine/metabolic 1.05 0.977 – 1.12 0.195 906 10866 exclusion phecode
276.41 Acidosis Endocrine/metabolic 1.04 0.967 – 1.12 0.292 813 9862 exclusion phecode
276.42 Alkalosis Endocrine/metabolic 1 0.818 – 1.23 0.973 101 1053 exclusion phecode
276.5 Hypovolemia Endocrine/metabolic 1.03 0.989 – 1.08 0.146 2355 26504 exclusion phecode
276.6 Fluid overload Endocrine/metabolic 0.984 0.881 – 1.1 0.773 338 4228 exclusion phecode
276.8 Polydipsia Endocrine/metabolic 1 0.818 – 1.22 0.994 100 1224 exclusion phecode
277 Other disorders of metabolism Endocrine/metabolic 0.997 0.927 – 1.07 0.931 800 8467 exclusion phecode
277.4 Disorders of bilirubin excretion Endocrine/metabolic 0.963 0.861 – 1.08 0.513 331 3378 exclusion phecode
277.5 Other disorders of lipoid metabolism Endocrine/metabolic 0.995 0.852 – 1.16 0.95 176 2132 exclusion phecode
277.51 Lipoprotein disorders Endocrine/metabolic 0.7 0.511 – 0.959 0.0266 38 483 exclusion phecode
278 Overweight, obesity and other hyperalimentation Endocrine/metabolic 1.02 1 – 1.04 0.0539 8569 102682 exclusion phecode
278.1 Obesity Endocrine/metabolic 1.02 1 – 1.05 0.052 8433 101134 exclusion phecode
278.3 Localized adiposity Endocrine/metabolic 1.05 0.828 – 1.33 0.685 75 802 exclusion phecode
278.4 Abnormal weight gain Endocrine/metabolic 1.04 0.799 – 1.37 0.75 52 627 exclusion phecode
279 Disorders involving the immune mechanism Endocrine/metabolic 1.02 0.893 – 1.16 0.769 233 2364 exclusion phecode
279.1 Immunity deficiency Endocrine/metabolic 1.01 0.872 – 1.17 0.9 194 1984 exclusion phecode
279.11 Deficiency of humoral immunity Endocrine/metabolic 0.887 0.742 – 1.06 0.186 131 1313 exclusion phecode
279.7 Other immunological findings Endocrine/metabolic 0.928 0.81 – 1.06 0.277 227 2290 exclusion phecode
280 Iron deficiency anemias Hematopoietic 1.02 0.993 – 1.04 0.157 6465 72172 exclusion phecode
280.1
Iron deficiency anemias, unspecified or not due
Iron deficiency anemias, unspecified or not due to blood loss
 Hematopoietic 1.02 0.99 – 1.04 0.231 6180 69311 exclusion phecode
280.2
Iron deficiency anemia secondary to blood loss
Iron deficiency anemia secondary to blood loss (chronic)
 Hematopoietic 1.09 0.989 – 1.21 0.0824 422 4338 exclusion phecode
281 Other deficiency anemia Hematopoietic 1.03 0.962 – 1.1 0.405 932 10541 exclusion phecode
281.1 Megaloblastic anemia Hematopoietic 1.04 0.967 – 1.11 0.318 893 10104 exclusion phecode
281.11 Pernicious anemia Hematopoietic 1.07 0.985 – 1.16 0.112 618 7120 exclusion phecode
281.12 Other vitamin B12 deficiency anemia Hematopoietic 1.19 1.01 – 1.41 0.0362 149 1678 exclusion phecode
281.13 Folate-deficiency anemia Hematopoietic 0.84 0.714 – 0.989 0.0363 161 1725 exclusion phecode
281.9 Deficiency anemias Hematopoietic 0.897 0.659 – 1.22 0.489 46 514 exclusion phecode
282 Hereditary hemolytic anemias Hematopoietic 1.02 0.86 – 1.22 0.802 133 1422 exclusion phecode
282.8 Other hemoglobinopathies Hematopoietic 1.11 0.841 – 1.47 0.457 51 531 exclusion phecode
282.9 Other hereditary hemolytic anemias Hematopoietic 1.01 0.795 – 1.28 0.934 72 809 exclusion phecode
283 Acquired hemolytic anemias Hematopoietic 1.02 0.842 – 1.22 0.875 117 1290 exclusion phecode
283.1 Autoimmune hemolytic anemias Hematopoietic 0.951 0.77 – 1.17 0.638 89 996 exclusion phecode
284 Aplastic anemia Hematopoietic 0.985 0.886 – 1.09 0.775 379 4117 exclusion phecode
285 Other anemias Hematopoietic 1 0.98 – 1.02 0.972 10456 114585 exclusion phecode
285.1 Acute posthemorrhagic anemia Hematopoietic 0.981 0.864 – 1.11 0.77 253 2590 exclusion phecode
285.2 Anemia of chronic disease Hematopoietic 1.01 0.925 – 1.1 0.848 573 6568 exclusion phecode
285.22 Anemia in neoplastic disease Hematopoietic 1.02 0.914 – 1.13 0.757 381 3904 exclusion phecode
286 Coagulation defects Hematopoietic 0.991 0.923 – 1.06 0.808 825 8736 exclusion phecode
286.1 Congenital coagulation defects Hematopoietic 0.997 0.902 – 1.1 0.956 416 4369 exclusion phecode
286.11 Von willebrand's disease Hematopoietic 1.04 0.836 – 1.28 0.747 91 918 exclusion phecode
286.12
Congenital deficiency of other clotting factors
Congenital deficiency of other clotting factors (including factor VII)
 Hematopoietic 0.986 0.867 – 1.12 0.832 261 2795 exclusion phecode
286.13 Congenital factor VIII disorder Hematopoietic 1.19 0.909 – 1.55 0.208 55 597 exclusion phecode
286.5
Hemorrhagic disorder due to intrinsic
Hemorrhagic disorder due to intrinsic circulating anticoagulants
 Hematopoietic 0.96 0.758 – 1.22 0.736 72 797 exclusion phecode
286.7 Other and unspecified coagulation defects Hematopoietic 1.01 0.911 – 1.13 0.792 346 3660 exclusion phecode
287 Purpura and other hemorrhagic conditions Hematopoietic 1.02 0.964 – 1.07 0.519 1469 15512 exclusion phecode
287.1 Spontaneous ecchymoses Hematopoietic 0.916 0.756 – 1.11 0.372 111 1211 exclusion phecode
287.2 Allergic purpura Hematopoietic 1.07 0.781 – 1.47 0.671 45 486 exclusion phecode
287.3 Thrombocytopenia Hematopoietic 1 0.946 – 1.06 0.977 1383 14596 exclusion phecode
287.31 Primary thrombocytopenia Hematopoietic 1.03 0.923 – 1.15 0.618 374 3961 exclusion phecode
287.32 Secondary thrombocytopenia Hematopoietic 0.949 0.736 – 1.23 0.69 65 710 exclusion phecode
288 Diseases of white blood cells Hematopoietic 1.01 0.979 – 1.05 0.434 3503 35525 exclusion phecode
288.1 Decreased white blood cell count Hematopoietic 1.02 0.98 – 1.06 0.363 2964 29932 exclusion phecode
288.11 Neutropenia Hematopoietic 1.02 0.98 – 1.06 0.363 2971 30014 exclusion phecode
288.3 Eosinophilia Hematopoietic 0.983 0.765 – 1.26 0.892 62 663 exclusion phecode
289 Other diseases of blood and blood-forming organs Hematopoietic 0.964 0.895 – 1.04 0.325 774 8112 exclusion phecode
289.3
Personal history of diseases of blood and
Personal history of diseases of blood and blood-forming organs
 Hematopoietic 0.982 0.866 – 1.11 0.78 259 2760 exclusion phecode
289.4 Lymphadenitis Hematopoietic 0.984 0.943 – 1.03 0.456 2355 24586 exclusion phecode
289.5 Diseases of spleen Hematopoietic 1.05 0.956 – 1.16 0.293 434 4831 exclusion phecode
289.8 Polycythemia, secondary Hematopoietic 1.01 0.888 – 1.15 0.872 254 2705 exclusion phecode
289.9 Abnormality of red blood cells Hematopoietic 0.861 0.685 – 1.08 0.197 76 842 exclusion phecode
290
Delirium dementia and amnestic and other
Delirium dementia and amnestic and other cognitive disorders
 Mental Disorders 0.977 0.929 – 1.03 0.359 1641 17903 exclusion phecode
290.1 Dementias Mental Disorders 0.948 0.884 – 1.02 0.132 857 9276 exclusion phecode
290.11 Alzheimer's disease Mental Disorders 0.984 0.887 – 1.09 0.764 386 3981 exclusion phecode
290.16 Vascular dementia Mental Disorders 0.955 0.81 – 1.13 0.588 152 1848 exclusion phecode
290.2 Delirium due to conditions classified elsewhere Mental Disorders 1.02 0.933 – 1.11 0.678 539 6035 exclusion phecode
290.3
Other persistent mental disorders due to
Other persistent mental disorders due to conditions classified elsewhere
 Mental Disorders 0.976 0.765 – 1.25 0.848 66 689 exclusion phecode
291
Other specified nonpsychotic and/or transient
Other specified nonpsychotic and/or transient mental disorders
 Mental Disorders 0.998 0.925 – 1.08 0.969 722 7929 exclusion phecode
291.1
Transient mental disorders due to conditions
Transient mental disorders due to conditions classified elsewhere
 Mental Disorders 0.965 0.799 – 1.17 0.714 113 1266 exclusion phecode
291.4
Specific nonpsychotic mental disorders due to
Specific nonpsychotic mental disorders due to brain damage
 Mental Disorders 0.964 0.847 – 1.1 0.576 252 2680 exclusion phecode
291.8 Alteration of consciousness Mental Disorders 1.05 0.949 – 1.17 0.324 373 4141 exclusion phecode
292 Neurological disorders Mental Disorders 1.01 0.976 – 1.04 0.624 3987 43204 exclusion phecode
292.1 Aphasia/speech disturbance Mental Disorders 1 0.946 – 1.06 0.951 1287 14150 exclusion phecode
292.2 Mild cognitive impairment Mental Disorders 1.01 0.865 – 1.19 0.861 159 1770 exclusion phecode
292.3 Memory loss Mental Disorders 1.07 0.988 – 1.16 0.096 644 6520 exclusion phecode
292.4 Altered mental status Mental Disorders 1.01 0.959 – 1.06 0.806 1820 20305 exclusion phecode
292.6 Hallucinations Mental Disorders 0.956 0.843 – 1.08 0.485 269 2892 exclusion phecode
293 Symptoms involving head and neck Mental Disorders 0.957 0.913 – 1 0.0718 1873 19540 exclusion phecode
293.1
Swelling, mass, or lump in head and neck
Swelling, mass, or lump in head and neck [Space-occupying lesion, intracranial NOS]
 Mental Disorders 1.02 0.952 – 1.1 0.545 831 8486 exclusion phecode
295 Schizophrenia and other psychotic disorders Mental Disorders 0.91 0.842 – 0.982 0.0154 730 8042 exclusion phecode
295.1 Schizophrenia Mental Disorders 0.891 0.812 – 0.979 0.0159 495 5507 exclusion phecode
295.2 Paranoid disorders Mental Disorders 0.967 0.816 – 1.15 0.702 152 1690 exclusion phecode
295.3 Psychosis Mental Disorders 0.867 0.74 – 1.02 0.08 155 1622 exclusion phecode
296 Mood disorders Mental Disorders 1.01 0.99 – 1.03 0.345 11154 118283 exclusion phecode
296.1 Bipolar Mental Disorders 0.955 0.894 – 1.02 0.172 949 10113 exclusion phecode
296.2 Depression Mental Disorders 1.01 0.992 – 1.03 0.225 10575 112246 exclusion phecode
296.22 Major depressive disorder Mental Disorders 0.898 0.802 – 1.01 0.0618 317 3450 exclusion phecode
297.2 Suicide or self-inflicted injury Mental Disorders 1.07 0.951 – 1.21 0.25 276 2948 exclusion phecode
300 Anxiety disorders Mental Disorders 1.01 0.984 – 1.04 0.436 6285 65322 exclusion phecode
300.1 Anxiety disorder Mental Disorders 1.01 0.984 – 1.04 0.42 5813 60361 exclusion phecode
300.11 Generalized anxiety disorder Mental Disorders 0.995 0.836 – 1.18 0.952 137 1422 exclusion phecode
300.12 Agorophobia, social phobia, and panic disorder Mental Disorders 1.04 0.957 – 1.12 0.375 650 6752 exclusion phecode
300.13 Phobia Mental Disorders 1.01 0.921 – 1.12 0.766 453 4783 exclusion phecode
300.3 Obsessive-compulsive disorders Mental Disorders 1.1 0.92 – 1.31 0.301 131 1352 exclusion phecode
300.4 Dysthymic disorder Mental Disorders 1.05 0.785 – 1.41 0.729 47 498 exclusion phecode
300.8 Acute reaction to stress Mental Disorders 1.11 0.921 – 1.35 0.266 112 1186 exclusion phecode
300.9 Posttraumatic stress disorder Mental Disorders 0.875 0.716 – 1.07 0.194 102 1082 exclusion phecode
301 Personality disorders Mental Disorders 1.01 0.894 – 1.14 0.887 276 3211 exclusion phecode
301.2 Antisocial/borderline personality disorder Mental Disorders 0.995 0.818 – 1.21 0.956 100 1151 exclusion phecode
302 Sexual and gender identity disorders Mental Disorders 1.1 0.961 – 1.26 0.163 231 2630 exclusion phecode
303 Psychogenic and somatoform disorders Mental Disorders 1.03 0.934 – 1.13 0.562 437 4460 exclusion phecode
303.3 Psychogenic disorder Mental Disorders 1.02 0.915 – 1.14 0.685 333 3341 exclusion phecode
303.4 Somatoform disorder Mental Disorders 1.1 0.912 – 1.34 0.309 110 1186 exclusion phecode
304 Adjustment reaction Mental Disorders 0.941 0.829 – 1.07 0.344 263 2829 exclusion phecode
305.2 Eating disorder Mental Disorders 1.06 0.845 – 1.32 0.631 80 868 exclusion phecode
306 Other mental disorder Mental Disorders 1.03 1.02 – 1.05 1.73e-06 24886 217816 exclusion phecode
306.9 Tension headache Mental Disorders 0.985 0.874 – 1.11 0.799 289 3047 exclusion phecode
313 Pervasive developmental disorders Mental Disorders 0.819 0.642 – 1.04 0.107 63 732 exclusion phecode
313.3 Autism Mental Disorders 0.774 0.579 – 1.03 0.084 42 511 exclusion phecode
315 Develomental delays and disorders Mental Disorders 1.12 0.997 – 1.26 0.0569 302 3293 exclusion phecode
315.1 Learning disorder Mental Disorders 1.06 0.883 – 1.27 0.534 125 1539 exclusion phecode
315.2 Speech and language disorder Mental Disorders 1.19 0.93 – 1.52 0.167 76 806 exclusion phecode
316 Substance addiction and disorders Mental Disorders 1.02 0.991 – 1.05 0.183 4802 50004 exclusion phecode
316.1 Polyneuropathy due to drugs Mental Disorders 1.31 1.01 – 1.7 0.0414 55 568 exclusion phecode
317 Alcohol-related disorders Mental Disorders 1.02 1 – 1.04 0.0313 11642 119575 exclusion phecode
317.1 Alcoholism Mental Disorders 1.03 1.01 – 1.05 0.0157 8145 83748 exclusion phecode
317.11 Alcoholic liver damage Mental Disorders 1.05 0.971 – 1.14 0.223 674 7891 exclusion phecode
318 Tobacco use disorder Mental Disorders 1.04 1.03 – 1.06 1.8e-07 17504 175090 exclusion phecode
320 Meningitis Neurological 1.02 0.92 – 1.12 0.747 413 4228 exclusion phecode
323 Encephalitis Neurological 0.967 0.863 – 1.08 0.558 320 3246 exclusion phecode
323.2 Acute (transverse) myelitis Neurological 0.886 0.692 – 1.13 0.337 69 704 exclusion phecode
324 Other CNS infection and poliomyelitis Neurological 0.999 0.878 – 1.14 0.993 265 2741 exclusion phecode
327 Sleep disorders Neurological 0.998 0.935 – 1.06 0.947 991 10938 exclusion phecode
327.3 Sleep apnea Neurological 1.05 1.02 – 1.09 0.00268 3577 41582 exclusion phecode
327.4 Insomnia Neurological 0.969 0.819 – 1.15 0.719 147 1575 exclusion phecode
327.41 Organic or persistent insomnia Neurological 0.972 0.808 – 1.17 0.763 125 1325 exclusion phecode
331 Other cerebral degenerations Neurological 0.984 0.923 – 1.05 0.625 1005 10696 exclusion phecode
331.1 Hydrocephalus Neurological 0.989 0.901 – 1.08 0.81 464 4760 exclusion phecode
331.9 Cerebral degeneration, unspecified Neurological 1.01 0.91 – 1.13 0.8 356 4011 exclusion phecode
332 Parkinson's disease Neurological 0.945 0.887 – 1.01 0.083 1036 10429 exclusion phecode
333
Extrapyramidal disease and abnormal movement
Extrapyramidal disease and abnormal movement disorders
 Neurological 0.956 0.889 – 1.03 0.228 802 8440 exclusion phecode
333.1 Essential tremor Neurological 0.897 0.773 – 1.04 0.154 187 2008 exclusion phecode
333.2 Myoclonus Neurological 1.2 0.964 – 1.5 0.102 86 910 exclusion phecode
333.4 Torsion dystonia Neurological 0.941 0.826 – 1.07 0.366 233 2398 exclusion phecode
334 Degenerative disease of the spinal cord Neurological 1.06 1.01 – 1.12 0.0165 1634 17019 exclusion phecode
334.1 Spinocerebellar disease Neurological 1.02 0.829 – 1.24 0.882 107 1105 exclusion phecode
334.2 Anterior horn cell disease Neurological 1.06 0.926 – 1.22 0.393 221 2292 exclusion phecode
335 Multiple sclerosis Neurological 0.91 0.859 – 0.964 0.00147 1260 12798 exclusion phecode
337 Disorders of the autonomic nervous system Neurological 1.04 0.906 – 1.18 0.609 228 2499 exclusion phecode
337.1 Peripheral autonomic neuropathy Neurological 0.866 0.666 – 1.13 0.282 59 669 exclusion phecode
338 Pain Neurological 1.08 0.997 – 1.16 0.0606 699 7279 exclusion phecode
338.1 Acute pain Neurological 1.12 1 – 1.25 0.0435 356 3713 exclusion phecode
338.2 Chronic pain Neurological 1.06 0.952 – 1.18 0.286 349 3627 exclusion phecode
339 Other headache syndromes Neurological 1.05 1.02 – 1.07 0.000105 7225 74386 exclusion phecode
340 Migraine Neurological 0.973 0.936 – 1.01 0.183 2697 27382 exclusion phecode
340.1 Migrain with aura Neurological 0.864 0.749 – 0.995 0.0424 200 2024 exclusion phecode
341
Other demyelinating diseases of central nervous
Other demyelinating diseases of central nervous system
 Neurological 1.12 0.974 – 1.28 0.113 234 2434 exclusion phecode
342 Hemiplegia Neurological 1.02 0.967 – 1.08 0.421 1275 14011 exclusion phecode
343 Infantile cerebral palsy Neurological 1.13 0.957 – 1.34 0.147 132 1366 exclusion phecode
344 Other paralytic syndromes Neurological 1.07 0.983 – 1.16 0.119 590 6208 exclusion phecode
345 Epilepsy, recurrent seizures, convulsions Neurological 1.02 0.994 – 1.06 0.113 4610 47531 exclusion phecode
345.1 Epilepsy Neurological 1 0.933 – 1.08 0.954 791 8226 exclusion phecode
345.11 Generalized convulsive epilepsy Neurological 1.03 0.929 – 1.14 0.582 395 4182 exclusion phecode
345.12 Partial epilepsy Neurological 1 0.885 – 1.14 0.955 259 2640 exclusion phecode
345.3 Convulsions Neurological 0.993 0.95 – 1.04 0.77 2042 21119 exclusion phecode
346.1
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of skull and head
 Neurological 1.05 0.879 – 1.26 0.587 127 1338 exclusion phecode
348 Other conditions of brain Neurological 1.02 0.941 – 1.1 0.659 678 7378 exclusion phecode
348.2 Cerebral edema and compression of brain Neurological 1.03 0.904 – 1.18 0.647 238 2553 exclusion phecode
348.4 Cerebral cysts Neurological 0.82 0.679 – 0.99 0.0386 120 1284 exclusion phecode
348.7 Coma Neurological 1.1 0.981 – 1.22 0.105 330 3373 exclusion phecode
348.8 Encephalopathy, not elsewhere classified Neurological 1.15 0.994 – 1.32 0.0611 208 2345 exclusion phecode
348.9 Other conditions of brain, NOS Neurological 0.903 0.81 – 1.01 0.0652 346 3702 exclusion phecode
349
Other and unspecified disorders of the nervous
Other and unspecified disorders of the nervous system
 Neurological 1.01 0.899 – 1.13 0.875 302 3234 exclusion phecode
350 Abnormal movement Neurological 1.04 0.997 – 1.09 0.0688 2322 25008 exclusion phecode
350.1 Abnormal involuntary movements Neurological 1.1 1.02 – 1.18 0.0127 799 8332 exclusion phecode
350.2 Abnormality of gait Neurological 1.01 0.954 – 1.07 0.762 1358 14903 exclusion phecode
350.3 Lack of coordination Neurological 1.06 0.943 – 1.19 0.338 316 3416 exclusion phecode
350.6 Disturbances of sensation of smell and taste Neurological 1.22 0.908 – 1.63 0.188 50 508 exclusion phecode
351 Other peripheral nerve disorders Neurological 1.03 1.01 – 1.05 0.0106 11191 118192 exclusion phecode
352 Disorders of other cranial nerves Neurological 1 0.947 – 1.06 0.89 1234 12993 exclusion phecode
352.1 Trigeminal nerve disorders [CN5] Neurological 0.965 0.875 – 1.06 0.472 435 4427 exclusion phecode
352.2 Facial nerve disorders [CN7] Neurological 1.02 0.944 – 1.09 0.672 776 8326 exclusion phecode
353 Nerve root and plexus disorders Neurological 1.06 0.99 – 1.12 0.0994 1036 10700 exclusion phecode
353.1 Nerve plexus lesions Neurological 0.976 0.804 – 1.19 0.808 109 1084 exclusion phecode
353.2 Nerve root lesions Neurological 1.12 0.837 – 1.51 0.439 52 533 exclusion phecode
356 Hereditary and idiopathic peripheral neuropathy Neurological 0.757 0.633 – 0.906 0.00235 137 1416 exclusion phecode
357 Inflammatory and toxic neuropathy Neurological 1.06 0.999 – 1.13 0.0527 1068 12730 exclusion phecode
358 Myoneural disorders Neurological 0.922 0.794 – 1.07 0.29 190 1980 exclusion phecode
358.1 Myasthenia gravis Neurological 0.917 0.783 – 1.07 0.28 172 1804 exclusion phecode
359 Muscular dystrophies and other myopathies Neurological 1.1 0.994 – 1.22 0.0658 400 4400 exclusion phecode
359.1 Muscular dystrophies Neurological 1.21 1 – 1.47 0.0505 116 1151 exclusion phecode
359.2 Myopathy Neurological 1.07 0.954 – 1.21 0.242 299 3404 exclusion phecode
360 Disorders of the globe Sense Organs 1.06 0.938 – 1.19 0.366 312 3184 exclusion phecode
360.2 Progressive myopia Sense Organs 1.08 0.946 – 1.24 0.251 235 2374 exclusion phecode
361 Retinal detachments and defects Sense Organs 0.982 0.946 – 1.02 0.339 3031 30390 exclusion phecode
361.1 Retinal detachment with retinal defect Sense Organs 0.989 0.934 – 1.05 0.711 1306 13014 exclusion phecode
361.2 Retinoschisis and retinal cysts Sense Organs 0.873 0.671 – 1.14 0.314 60 639 exclusion phecode
362 Other retinal disorders Sense Organs 0.999 0.964 – 1.04 0.965 3251 35990 exclusion phecode
362.2
Degeneration of macula and posterior pole of
Degeneration of macula and posterior pole of retina
 Sense Organs 0.988 0.943 – 1.04 0.621 1902 20471 exclusion phecode
362.29 Macular degeneration (senile) of retina NOS Sense Organs 0.988 0.943 – 1.04 0.621 1900 20441 exclusion phecode
362.3 Other nondiabetic retinopathy Sense Organs 1.14 0.943 – 1.38 0.176 127 1516 exclusion phecode
362.31 Separation of retinal layers Sense Organs 1.12 0.9 – 1.39 0.31 92 926 exclusion phecode
362.4 Retinal vascular changes and abnomalities Sense Organs 1.03 0.953 – 1.11 0.468 700 7915 exclusion phecode
362.6 Peripheral retinal degenerations Sense Organs 0.982 0.838 – 1.15 0.821 166 1712 exclusion phecode
362.7 Hereditary retinal dystrophies Sense Organs 1.14 0.912 – 1.42 0.253 79 773 exclusion phecode
362.8 Retinal hemorrhage/ischemia Sense Organs 0.954 0.778 – 1.17 0.653 102 1090 exclusion phecode
363
Chorioretinal inflammations, scars, and other
Chorioretinal inflammations, scars, and other disorders of choroid
 Sense Organs 0.82 0.697 – 0.965 0.0172 150 1614 exclusion phecode
363.3 Chorioretinal scars Sense Organs 0.7 0.529 – 0.926 0.0125 53 661 exclusion phecode
364 Corneal opacity and other disorders of cornea Sense Organs 0.967 0.889 – 1.05 0.434 587 6070 exclusion phecode
364.1 Corneal opacity Sense Organs 1.01 0.806 – 1.26 0.943 81 847 exclusion phecode
364.2 Corneal edema Sense Organs 1.05 0.828 – 1.34 0.677 71 741 exclusion phecode
364.4 Corneal degenerations Sense Organs 1.01 0.861 – 1.18 0.938 173 1891 exclusion phecode
364.41 Keratoconus Sense Organs 0.893 0.716 – 1.11 0.317 81 824 exclusion phecode
364.5 Corneal dystrophy Sense Organs 0.902 0.78 – 1.04 0.163 198 1990 exclusion phecode
364.9 Cornea replaced by transplant Sense Organs 1.03 0.832 – 1.27 0.798 93 939 exclusion phecode
365 Glaucoma Sense Organs 1.03 0.997 – 1.06 0.0763 3986 41133 exclusion phecode
365.1 Open-angle glaucoma Sense Organs 1.07 0.998 – 1.14 0.0589 938 9624 exclusion phecode
365.11 Primary open angle glaucoma Sense Organs 1.06 0.991 – 1.13 0.0889 932 9574 exclusion phecode
365.2 Primary angle-closure glaucoma Sense Organs 0.965 0.89 – 1.05 0.38 649 6579 exclusion phecode
366 Cataract Sense Organs 1.01 0.993 – 1.02 0.302 17642 158330 exclusion phecode
366.1 Nonsenile Cataract Sense Organs 1.15 0.904 – 1.46 0.254 65 669 exclusion phecode
366.2 Senile cataract Sense Organs 1.02 0.993 – 1.04 0.166 7293 76693 exclusion phecode
366.3 Traumatic cataract Sense Organs 1.07 0.861 – 1.33 0.541 94 928 exclusion phecode
367
Disorders of refraction and accommodation
Disorders of refraction and accommodation; blindness and low vision
 Sense Organs 1.02 0.977 – 1.07 0.362 2194 22670 exclusion phecode
367.1 Myopia Sense Organs 1.02 0.962 – 1.09 0.477 1159 11766 exclusion phecode
367.2 Astigmatism Sense Organs 0.99 0.849 – 1.15 0.895 178 1793 exclusion phecode
367.8 Hypermetropia Sense Organs 0.937 0.821 – 1.07 0.338 241 2395 exclusion phecode
367.9 Blindness and low vision Sense Organs 1.07 0.981 – 1.16 0.13 616 6764 exclusion phecode
368 Visual disturbances Sense Organs 1.02 0.976 – 1.06 0.436 2668 27947 exclusion phecode
368.1 Amblyopia Sense Organs 0.877 0.796 – 0.966 0.0078 465 4962 exclusion phecode
368.2 Diplopia and disorders of binocular vision Sense Organs 1.03 0.947 – 1.11 0.525 658 6893 exclusion phecode
368.3 Anisometropia Sense Organs 1.21 1.02 – 1.43 0.0304 145 1440 exclusion phecode
368.4 Visual field defects Sense Organs 0.975 0.865 – 1.1 0.684 288 3118 exclusion phecode
368.9 Subjective visual disturbances Sense Organs 1.06 0.969 – 1.15 0.213 559 5794 exclusion phecode
369 Infection of the eye Sense Organs 1.04 0.945 – 1.13 0.458 508 5221 exclusion phecode
369.2 Eye infection, viral Sense Organs 0.924 0.764 – 1.12 0.411 117 1175 exclusion phecode
369.5 Conjunctivitis, infectious Sense Organs 1.06 0.914 – 1.23 0.437 194 2013 exclusion phecode
370 Keratitis Sense Organs 0.978 0.861 – 1.11 0.73 255 2702 exclusion phecode
370.1 Corneal ulcer Sense Organs 0.97 0.814 – 1.16 0.732 127 1334 exclusion phecode
371 Inflammation of the eye Sense Organs 0.976 0.939 – 1.01 0.216 2863 28793 exclusion phecode
371.1 Uveitis, noninfectious or NOS Sense Organs 0.943 0.854 – 1.04 0.248 436 4569 exclusion phecode
371.3 Inflammation of eyelids Sense Organs 0.989 0.947 – 1.03 0.608 2236 22240 exclusion phecode
372 Disorders of conjunctiva Sense Organs 0.922 0.853 – 0.996 0.0401 707 7142 exclusion phecode
374 Other disorders of eyelids Sense Organs 1.02 0.989 – 1.05 0.24 5212 53459 exclusion phecode
374.1 Ectropion or entropion Sense Organs 1.02 0.951 – 1.09 0.635 951 9879 exclusion phecode
374.3 Ptosis of eyelid Sense Organs 1.07 1.01 – 1.12 0.0113 1675 17171 exclusion phecode
375 Disorders of lacrimal system Sense Organs 1.03 0.987 – 1.08 0.166 2031 20754 exclusion phecode
375.2 Epiphora Sense Organs 0.994 0.926 – 1.07 0.878 826 8400 exclusion phecode
376 Disorders of the orbit Sense Organs 0.977 0.777 – 1.23 0.84 78 807 exclusion phecode
377 Disorders of optic nerve and visual pathways Sense Organs 1.06 0.945 – 1.19 0.316 327 3423 exclusion phecode
377.1 Optic atrophy Sense Organs 0.959 0.715 – 1.29 0.783 50 535 exclusion phecode
377.3 Optic neuritis/neuropathy Sense Organs 1.1 0.907 – 1.33 0.336 115 1197 exclusion phecode
378
Strabismus and other disorders of binocular eye
Strabismus and other disorders of binocular eye movements
 Sense Organs 1 0.948 – 1.06 0.91 1294 13387 exclusion phecode
378.1 Strabismus (not specified as paralytic) Sense Organs 0.974 0.908 – 1.04 0.455 854 8629 exclusion phecode
378.2 Nystagmus and other irregular eye movements Sense Organs 1.13 0.971 – 1.31 0.117 188 2006 exclusion phecode
378.5 Paralytic strabismus Sense Organs 1.02 0.893 – 1.16 0.778 243 2625 exclusion phecode
379 Other disorders of eye Sense Organs 1.01 0.971 – 1.04 0.71 3229 34624 exclusion phecode
379.2 Disorders of vitreous body Sense Organs 0.995 0.936 – 1.06 0.869 1155 12781 exclusion phecode
379.3 Aphakia and other disorders of lens Sense Organs 1.02 0.967 – 1.07 0.496 1597 16868 exclusion phecode
379.4 Anomalies of pupillary function Sense Organs 1.46 1.13 – 1.88 0.00328 69 668 exclusion phecode
379.5 Disorders of iris and ciliary body Sense Organs 1.02 0.919 – 1.14 0.68 357 3776 exclusion phecode
379.9 Pain, swelling or discharge of eye Sense Organs 1.05 0.887 – 1.23 0.598 150 1609 exclusion phecode
380 Disorders of external ear Sense Organs 0.989 0.909 – 1.08 0.795 581 6004 exclusion phecode
380.1 Otitis externa Sense Organs 1.03 0.939 – 1.14 0.502 439 4850 exclusion phecode
380.4 Impacted cerumen Sense Organs 1.15 1.03 – 1.29 0.0156 332 3387 exclusion phecode
381 Otitis media and Eustachian tube disorders Sense Organs 1.04 0.994 – 1.09 0.086 1970 20237 exclusion phecode
381.1 Otitis media Sense Organs 1.06 1.01 – 1.11 0.0281 1609 16620 exclusion phecode
381.11 Suppurative and unspecified otitis media Sense Organs 1.08 1 – 1.16 0.0507 781 8014 exclusion phecode
381.2 Eustachian tube disorders Sense Organs 0.929 0.8 – 1.08 0.334 185 1831 exclusion phecode
381.3 Mastoiditis & related conditions Sense Organs 1.19 1 – 1.41 0.0446 152 1613 exclusion phecode
381.9 Otorrhea Sense Organs 1.01 0.892 – 1.15 0.834 254 2647 exclusion phecode
382 Otalgia Sense Organs 0.985 0.874 – 1.11 0.81 286 2916 exclusion phecode
383 Otosclerosis Sense Organs 0.912 0.81 – 1.03 0.123 299 2952 exclusion phecode
384 Other disorders of tympanic membrane Sense Organs 1.11 1.04 – 1.18 0.000646 1212 12284 exclusion phecode
384.4 Perforation of tympanic membrane Sense Organs 1.14 1.07 – 1.22 8.91e-05 975 9877 exclusion phecode
385 Other disorders of middle ear and mastoid Sense Organs 1.08 1 – 1.17 0.0415 727 7369 exclusion phecode
385.3 Cholesteatoma Sense Organs 1.06 0.972 – 1.15 0.192 562 5687 exclusion phecode
385.5
Tympanosclerosis and middle ear disease related
Tympanosclerosis and middle ear disease related to otitis media
 Sense Organs 1.08 0.941 – 1.24 0.28 225 2279 exclusion phecode
386
Vertiginous syndromes and other disorders of
Vertiginous syndromes and other disorders of vestibular system
 Sense Organs 1.02 0.966 – 1.07 0.533 1614 16424 exclusion phecode
386.1 Meniere's disease Sense Organs 0.972 0.889 – 1.06 0.529 544 5454 exclusion phecode
386.2 Peripheral or central vertigo Sense Organs 0.963 0.862 – 1.08 0.509 344 3533 exclusion phecode
386.3 Labyrinthitis Sense Organs 1.06 0.985 – 1.15 0.118 708 7253 exclusion phecode
386.9
Dizziness and giddiness (Light-headedness and
Dizziness and giddiness (Light-headedness and vertigo)
 Sense Organs 1.04 1 – 1.07 0.0299 4162 43123 exclusion phecode
388 Other disorders of ear Sense Organs 1.08 0.934 – 1.25 0.292 186 1909 exclusion phecode
389 Hearing loss Sense Organs 1.04 1 – 1.07 0.0383 3771 39261 exclusion phecode
389.1 Sensorineural hearing loss Sense Organs 0.987 0.892 – 1.09 0.804 408 4262 exclusion phecode
389.2 Conductive hearing loss Sense Organs 1.07 0.965 – 1.18 0.207 416 4232 exclusion phecode
389.4 Tinnitus Sense Organs 1.07 0.977 – 1.18 0.139 479 4815 exclusion phecode
394 Rheumatic disease of the heart valves Circulatory System 1.01 0.976 – 1.04 0.689 4358 45542 exclusion phecode
394.2 Mitral valve disease Circulatory System 1.01 0.972 – 1.05 0.595 2682 27877 exclusion phecode
394.3 Aortic valve disease Circulatory System 0.992 0.933 – 1.05 0.793 1134 11851 exclusion phecode
394.7 Disease of tricuspid valve Circulatory System 1.02 0.952 – 1.09 0.59 929 9798 exclusion phecode
395 Heart valve disorders Circulatory System 1.01 0.978 – 1.05 0.495 3742 39314 exclusion phecode
395.1 Nonrheumatic mitral valve disorders Circulatory System 1.01 0.966 – 1.05 0.79 2588 26939 exclusion phecode
395.2 Nonrheumatic aortic valve disorders Circulatory System 0.999 0.872 – 1.14 0.992 229 2553 exclusion phecode
395.3 Nonrheumatic tricuspid valve disorders Circulatory System 0.928 0.746 – 1.15 0.499 89 963 exclusion phecode
395.4 Nonrheumatic pulmonary valve disorders Circulatory System 0.902 0.721 – 1.13 0.362 85 899 exclusion phecode
395.6 Heart valve replaced Circulatory System 1.03 0.97 – 1.09 0.372 1308 13910 exclusion phecode
396 Abnormal heart sounds Circulatory System 1.05 0.982 – 1.12 0.15 955 9935 exclusion phecode
401 Hypertension Circulatory System 1.07 1.06 – 1.08 1.05e-49 63455 258352 exclusion phecode
401.1 Essential hypertension Circulatory System 1.07 1.06 – 1.08 4.62e-49 63258 258135 exclusion phecode
401.2 Hypertensive heart and/or renal disease Circulatory System 1.11 1.05 – 1.17 4e-04 1356 18130 exclusion phecode
401.21 Hypertensive heart disease Circulatory System 1.09 0.963 – 1.22 0.181 287 3498 exclusion phecode
401.22 Hypertensive chronic kidney disease Circulatory System 1.1 1.03 – 1.17 0.00277 1072 14761 exclusion phecode
401.3 Other hypertensive complications Circulatory System 1.22 1.02 – 1.48 0.0338 121 1384 exclusion phecode
402
Elevated blood pressure reading without
Elevated blood pressure reading without diagnosis of hypertension
 Circulatory System 1.08 1.03 – 1.15 0.00475 1324 14232 exclusion phecode
411 Ischemic Heart Disease Circulatory System 1.05 1.04 – 1.07 8.55e-16 26474 199521 exclusion phecode
411.1 Unstable angina (intermediate coronary syndrome) Circulatory System 1.05 1.02 – 1.08 0.00375 4203 48355 exclusion phecode
411.2 Myocardial infarction Circulatory System 1.07 1.04 – 1.09 1.25e-09 10031 105611 exclusion phecode
411.3 Angina pectoris Circulatory System 1.06 1.04 – 1.07 4.22e-09 13082 135305 exclusion phecode
411.4 Coronary atherosclerosis Circulatory System 1.06 1.05 – 1.08 1.29e-13 17076 145560 exclusion phecode
411.41 Aneurysm and dissection of heart Circulatory System 1.05 0.973 – 1.14 0.197 654 6607 exclusion phecode
411.8
Other chronic ischemic heart disease
Other chronic ischemic heart disease, unspecified
 Circulatory System 1.05 1.04 – 1.07 2.38e-08 12341 123757 exclusion phecode
411.9
Other acute and subacute forms of ischemic
Other acute and subacute forms of ischemic heart disease
 Circulatory System 1.05 0.984 – 1.12 0.14 1039 11418 exclusion phecode
414 Other forms of chronic heart disease Circulatory System 1.03 0.976 – 1.09 0.289 1503 17064 exclusion phecode
414.2 ASCVD Circulatory System 0.992 0.751 – 1.31 0.957 56 673 exclusion phecode
415 Pulmonary heart disease Circulatory System 0.975 0.944 – 1.01 0.124 4049 41907 exclusion phecode
415.11 Pulmonary embolism and infarction, acute Circulatory System 0.969 0.767 – 1.22 0.79 70 698 exclusion phecode
415.2 Chronic pulmonary heart disease Circulatory System 0.973 0.888 – 1.07 0.555 502 5580 exclusion phecode
415.21 Primary pulmonary hypertension Circulatory System 0.962 0.866 – 1.07 0.474 372 4175 exclusion phecode
416 Cardiomegaly Circulatory System 1.01 0.971 – 1.06 0.519 2238 24840 exclusion phecode
418 Nonspecific chest pain Circulatory System 1.04 1.03 – 1.06 9.46e-11 25725 255784 exclusion phecode
418.1 Precordial pain Circulatory System 1.02 0.987 – 1.06 0.207 3162 33658 exclusion phecode
420 Carditis Circulatory System 0.979 0.934 – 1.03 0.394 1865 19658 exclusion phecode
420.1 Myocarditis Circulatory System 1.04 0.861 – 1.26 0.678 121 1184 exclusion phecode
420.2 Pericarditis Circulatory System 0.966 0.91 – 1.03 0.255 1199 12513 exclusion phecode
420.21 Acute pericarditis Circulatory System 0.982 0.85 – 1.13 0.804 200 2095 exclusion phecode
420.22 Chronic pericarditis Circulatory System 1.14 0.929 – 1.4 0.21 102 1038 exclusion phecode
420.3 Endocarditis Circulatory System 1.01 0.93 – 1.09 0.837 621 6684 exclusion phecode
425 Cardiomyopathy Circulatory System 1.05 0.984 – 1.12 0.147 1106 11797 exclusion phecode
425.1 Primary/intrinsic cardiomyopathies Circulatory System 1.06 0.994 – 1.13 0.0759 1076 11476 exclusion phecode
425.11 Hypertrophic obstructive cardiomyopathy Circulatory System 0.941 0.781 – 1.13 0.525 123 1239 exclusion phecode
425.12 Other hypertrophic cardiomyopathy Circulatory System 0.932 0.787 – 1.1 0.415 153 1515 exclusion phecode
425.8 Other cardiomyopathy Circulatory System 0.782 0.587 – 1.04 0.0927 53 557 exclusion phecode
426 Cardiac conduction disorders Circulatory System 1.04 1.02 – 1.07 0.00131 5951 64423 exclusion phecode
426.2 Atrioventricular [AV] block Circulatory System 1.07 1.02 – 1.12 0.0095 1783 19598 exclusion phecode
426.21 First degree AV block Circulatory System 1.09 1.01 – 1.17 0.0181 824 9130 exclusion phecode
426.23 Second degree AV block Circulatory System 1.08 0.976 – 1.2 0.133 387 4169 exclusion phecode
426.24 Atrioventricular block, complete Circulatory System 1.1 1.01 – 1.21 0.034 491 5429 exclusion phecode
426.25 Other heart block Circulatory System 0.981 0.815 – 1.18 0.841 121 1215 exclusion phecode
426.3 Bundle branch block Circulatory System 1.06 1.02 – 1.1 0.00248 2874 31064 exclusion phecode
426.31 Right bundle branch block Circulatory System 1.03 0.969 – 1.08 0.387 1303 13843 exclusion phecode
426.32 Left bundle branch block Circulatory System 1.1 1.04 – 1.16 0.000609 1487 16322 exclusion phecode
426.4 Anomalous atrioventricular excitation Circulatory System 1.05 0.918 – 1.21 0.459 224 2201 exclusion phecode
426.8 Other cardiac conduction disorders Circulatory System 0.973 0.737 – 1.28 0.847 55 564 exclusion phecode
426.9 Cardiac pacemaker/device in situ Circulatory System 1.03 0.985 – 1.08 0.186 2065 23036 exclusion phecode
426.91 Cardiac pacemaker in situ Circulatory System 1.03 0.987 – 1.08 0.153 1901 21148 exclusion phecode
427 Cardiac dysrhythmias Circulatory System 1.01 0.998 – 1.03 0.0822 21632 193998 exclusion phecode
427.1 Paroxysmal tachycardia, unspecified Circulatory System 1.03 0.988 – 1.07 0.175 2884 30138 exclusion phecode
427.11 Paroxysmal supraventricular tachycardia Circulatory System 1.02 0.974 – 1.07 0.408 2122 22187 exclusion phecode
427.12 Paroxysmal ventricular tachycardia Circulatory System 1.07 0.998 – 1.15 0.0569 828 8689 exclusion phecode
427.2 Atrial fibrillation and flutter Circulatory System 1.01 0.993 – 1.03 0.236 12898 124582 exclusion phecode
427.3 Other specified cardiac dysrhythmias Circulatory System 1.04 1.01 – 1.08 0.0261 2910 30189 exclusion phecode
427.4 Cardiac arrest and ventricular fibrillation Circulatory System 1.03 0.968 – 1.1 0.333 1038 11070 exclusion phecode
427.41 Ventricular fibrillation and flutter Circulatory System 1.05 0.928 – 1.18 0.466 306 3215 exclusion phecode
427.42 Cardiac arrest Circulatory System 1.02 0.952 – 1.1 0.556 859 9182 exclusion phecode
427.5 Arrhythmia (cardiac) NOS Circulatory System 0.981 0.913 – 1.05 0.605 847 8931 exclusion phecode
427.6 Premature beats Circulatory System 0.994 0.907 – 1.09 0.901 495 5046 exclusion phecode
427.61 Supraventricular premature beats Circulatory System 1.06 0.871 – 1.28 0.574 110 1092 exclusion phecode
427.7 Tachycardia NOS Circulatory System 0.983 0.938 – 1.03 0.467 1922 20648 exclusion phecode
427.8 Sinoatrial node dysfunction (Bradycardia) Circulatory System 1.01 0.909 – 1.13 0.821 372 3768 exclusion phecode
427.9 Palpitations Circulatory System 1 0.967 – 1.04 0.981 3540 36229 exclusion phecode
428 Congestive heart failure; nonhypertensive Circulatory System 1.05 1.01 – 1.08 0.00402 4440 51854 exclusion phecode
428.1 Congestive heart failure (CHF) NOS Circulatory System 1.04 0.991 – 1.1 0.104 1530 19540 exclusion phecode
428.2 Heart failure NOS Circulatory System 1.04 1.01 – 1.08 0.0135 3573 41209 exclusion phecode
429
Ill-defined descriptions and complications of
Ill-defined descriptions and complications of heart disease
 Circulatory System 1.07 0.984 – 1.16 0.117 644 6769 exclusion phecode
429.1 Heart transplant/surgery Circulatory System 1.08 0.824 – 1.41 0.578 50 593 exclusion phecode
429.2 Abnormal function study of cardiovascular system Circulatory System 1.02 0.929 – 1.12 0.655 467 4932 exclusion phecode
429.3 Symptoms involving cardiovascular system Circulatory System 1.2 1.03 – 1.39 0.0194 178 1875 exclusion phecode
430 Intracranial hemorrhage Circulatory System 1.03 0.977 – 1.08 0.301 1728 17643 exclusion phecode
430.1 Subarachnoid hemorrhage Circulatory System 1.07 0.992 – 1.15 0.0826 792 7897 exclusion phecode
430.2 Intracerebral hemorrhage Circulatory System 0.983 0.909 – 1.06 0.657 682 7126 exclusion phecode
430.3 Subdural hemorrhage Circulatory System 1.04 0.909 – 1.18 0.588 245 2472 exclusion phecode
433 Cerebrovascular disease Circulatory System 1.03 1.01 – 1.06 0.00463 7542 81511 exclusion phecode
433.1 Occlusion and stenosis of precerebral arteries Circulatory System 1.08 1.02 – 1.16 0.0133 1002 10895 exclusion phecode
433.12 Cerebral atherosclerosis Circulatory System 1.16 0.999 – 1.34 0.0522 198 2083 exclusion phecode
433.2 Occlusion of cerebral arteries Circulatory System 1.04 1.01 – 1.08 0.0146 3595 39337 exclusion phecode
433.21
Cerebral artery occlusion, with cerebral
Cerebral artery occlusion, with cerebral infarction
 Circulatory System 1.1 1.04 – 1.17 0.000477 1398 15620 exclusion phecode
433.3 Cerebral ischemia Circulatory System 1.01 0.972 – 1.06 0.552 2491 26988 exclusion phecode
433.31 Transient cerebral ischemia Circulatory System 1.02 0.969 – 1.07 0.508 1841 19872 exclusion phecode
433.5 Cerebral aneurysm Circulatory System 1.06 0.95 – 1.17 0.312 375 3726 exclusion phecode
433.8 Late effects of cerebrovascular disease Circulatory System 1.02 0.963 – 1.09 0.45 1067 11931 exclusion phecode
440 Atherosclerosis Circulatory System 1.16 1.09 – 1.23 5.11e-06 1071 12769 exclusion phecode
440.1 Atherosclerosis of renal artery Circulatory System 1.26 1.02 – 1.55 0.0298 93 1050 exclusion phecode
440.2 Atherosclerosis of the extremities Circulatory System 1.12 1.03 – 1.22 0.00682 585 7417 exclusion phecode
440.9 Atherosclerosis of aorta Circulatory System 1.15 1.01 – 1.31 0.0398 240 2683 exclusion phecode
441 Vascular insufficiency of intestine Circulatory System 1.08 0.993 – 1.18 0.0721 547 5781 exclusion phecode
441.1 Acute vascular insufficiency of intestine Circulatory System 1.06 0.928 – 1.21 0.405 251 2662 exclusion phecode
442 Other aneurysm Circulatory System 0.993 0.944 – 1.04 0.778 1708 17490 exclusion phecode
442.1 Aortic aneurysm Circulatory System 0.996 0.941 – 1.05 0.893 1319 13408 exclusion phecode
442.11 Abdominal aortic aneurysm Circulatory System 1.01 0.942 – 1.09 0.736 820 8506 exclusion phecode
442.2 Aneurysm of iliac artery Circulatory System 0.927 0.75 – 1.15 0.486 94 917 exclusion phecode
442.3 Aneurysm of artery of lower extremity Circulatory System 1.09 0.92 – 1.29 0.322 146 1570 exclusion phecode
442.4 Arterial dissection Circulatory System 0.984 0.735 – 1.32 0.915 51 514 exclusion phecode
442.8 Aneurysm of other specified artery Circulatory System 0.922 0.79 – 1.08 0.3 185 1913 exclusion phecode
443 Peripheral vascular disease Circulatory System 1.04 1 – 1.08 0.0454 3006 36571 exclusion phecode
443.1 Raynaud's syndrome Circulatory System 0.999 0.939 – 1.06 0.985 1086 10870 exclusion phecode
443.7
Peripheral angiopathy in diseases classified
Peripheral angiopathy in diseases classified elsewhere
 Circulatory System 1.27 0.946 – 1.71 0.111 41 3589 exclusion phecode
443.8 Other specified peripheral vascular diseases Circulatory System 1.04 0.998 – 1.08 0.0653 2974 34365 exclusion phecode
443.9 Peripheral vascular disease, unspecified Circulatory System 1.07 1.02 – 1.12 0.00301 1922 23831 exclusion phecode
444 Arterial embolism and thrombosis Circulatory System 1.02 0.943 – 1.1 0.671 718 8610 exclusion phecode
444.1
Arterial embolism and thrombosis of lower
Arterial embolism and thrombosis of lower extremity artery
 Circulatory System 1.09 0.982 – 1.2 0.106 406 5146 exclusion phecode
446 Polyarteritis nodosa and allied conditions Circulatory System 1.08 0.999 – 1.16 0.0535 741 7678 exclusion phecode
446.4 Wegener's granulomatosis Circulatory System 1.05 0.897 – 1.24 0.529 172 1723 exclusion phecode
446.5 Giant cell arteritis Circulatory System 1.09 0.98 – 1.22 0.111 357 3634 exclusion phecode
446.9 Arteritis NOS Circulatory System 1.05 0.911 – 1.21 0.507 210 2248 exclusion phecode
447 Other disorders of arteries and arterioles Circulatory System 1.06 0.999 – 1.13 0.0537 1057 12339 exclusion phecode
447.1 Stricture of artery Circulatory System 1.13 1.04 – 1.22 0.00305 662 8034 exclusion phecode
448 Disease of capillaries Circulatory System 0.929 0.778 – 1.11 0.41 126 1350 exclusion phecode
450 Noninfectious disorders of lymphatic channels Circulatory System 0.981 0.903 – 1.07 0.643 622 6653 exclusion phecode
451 Phlebitis and thrombophlebitis Circulatory System 1 0.968 – 1.04 0.927 3583 37235 exclusion phecode
451.2
Phlebitis and thrombophlebitis of lower
Phlebitis and thrombophlebitis of lower extremities
 Circulatory System 1 0.966 – 1.04 0.952 3333 34673 exclusion phecode
452 Other venous embolism and thrombosis Circulatory System 1.03 0.938 – 1.12 0.572 504 5325 exclusion phecode
454 Varicose veins Circulatory System 0.988 0.969 – 1.01 0.244 10645 106214 exclusion phecode
454.1 Varicose veins of lower extremity Circulatory System 0.984 0.964 – 1 0.0979 10991 109279 exclusion phecode
454.11 Varicose veins of lower extremity, symptomtic Circulatory System 0.931 0.852 – 1.02 0.111 559 5934 exclusion phecode
455 Hemorrhoids Circulatory System 1 0.991 – 1.02 0.507 21963 221341 exclusion phecode
456 Chronic venous insufficiency [CVI] Circulatory System 0.809 0.687 – 0.953 0.0113 157 1731 exclusion phecode
457
Encounter for long-term (current) use of
Encounter for long-term (current) use of anticoagulants, antithrombotics, aspirin
 Circulatory System 0.943 0.765 – 1.16 0.585 93 886 exclusion phecode
458 Hypotension Circulatory System 0.996 0.968 – 1.02 0.782 5060 54226 exclusion phecode
458.1 Orthostatic hypotension Circulatory System 1.04 0.982 – 1.11 0.171 1127 12541 exclusion phecode
458.2 Iatrogenic hypotension Circulatory System 0.995 0.863 – 1.15 0.941 203 2184 exclusion phecode
458.9 Hypotension NOS Circulatory System 0.992 0.956 – 1.03 0.677 3061 32860 exclusion phecode
459 Other disorders of circulatory system Circulatory System 1.01 0.997 – 1.03 0.103 14299 150891 exclusion phecode
459.1 Hemorrhage NOS Circulatory System 1.1 0.913 – 1.32 0.317 127 1317 exclusion phecode
459.9 Circulatory disease NEC Circulatory System 1.02 0.999 – 1.03 0.0712 14148 149588 exclusion phecode
464 Acute sinusitis Respiratory 1.23 1.06 – 1.43 0.00668 179 1865 exclusion phecode
465
Acute upper respiratory infections of multiple
Acute upper respiratory infections of multiple or unspecified sites
 Respiratory 1.01 0.962 – 1.05 0.777 2081 21652 exclusion phecode
465.2 Acute pharyngitis Respiratory 0.992 0.921 – 1.07 0.828 767 7913 exclusion phecode
465.4 Acute laryngitis and tracheitis Respiratory 0.91 0.774 – 1.07 0.253 155 1573 exclusion phecode
470 Septal Deviations/Turbinate Hypertrophy Respiratory 1.02 0.989 – 1.05 0.217 4369 44045 exclusion phecode
471 Nasal polyps Respiratory 1.06 1.02 – 1.1 0.00204 3095 30910 exclusion phecode
472 Chronic pharyngitis and nasopharyngitis Respiratory 1.02 0.948 – 1.09 0.661 904 9064 exclusion phecode
473 Diseases of the larynx and vocal cords Respiratory 0.985 0.944 – 1.03 0.478 2338 23998 exclusion phecode
473.1 Chronic laryngitis Respiratory 0.896 0.731 – 1.1 0.289 92 976 exclusion phecode
473.3 Paralysis/spasm of vocal cords or larynx Respiratory 1.01 0.881 – 1.15 0.915 239 2490 exclusion phecode
473.4 Voice disturbance Respiratory 0.956 0.895 – 1.02 0.186 975 10113 exclusion phecode
474 Acute and chronic tonsillitis Respiratory 1.04 0.986 – 1.09 0.153 1679 16979 exclusion phecode
474.1 Acute tonsillitis Respiratory 1.09 0.992 – 1.19 0.0746 513 5287 exclusion phecode
474.2 Chronic tonsillitis and adenoiditis Respiratory 1.04 0.973 – 1.1 0.271 1070 10754 exclusion phecode
475 Chronic sinusitis Respiratory 1.04 0.997 – 1.08 0.0723 2423 24482 exclusion phecode
476 Allergic rhinitis Respiratory 0.997 0.934 – 1.06 0.926 994 10060 exclusion phecode
477 Epistaxis or throat hemorrhage Respiratory 1.02 0.98 – 1.07 0.286 2190 22832 exclusion phecode
478 Throat pain Respiratory 1 0.898 – 1.12 0.972 351 3573 exclusion phecode
479 Other upper respiratory disease Respiratory 1.02 0.987 – 1.06 0.23 3780 38512 exclusion phecode
480 Pneumonia Respiratory 0.993 0.971 – 1.01 0.494 9060 96649 exclusion phecode
480.1 Bacterial pneumonia Respiratory 0.975 0.949 – 1 0.0613 5822 62035 exclusion phecode
480.11 Pneumococcal pneumonia Respiratory 0.969 0.941 – 0.997 0.0279 5175 54956 exclusion phecode
480.12 Pseudomonal pneumonia Respiratory 1.26 1.01 – 1.57 0.0403 84 854 exclusion phecode
480.2 Viral pneumonia Respiratory 1.01 0.793 – 1.29 0.926 67 677 exclusion phecode
480.3 Pneumonia due to fungus (mycoses) Respiratory 0.927 0.748 – 1.15 0.487 91 921 exclusion phecode
480.5 Bronchopneumonia and lung abscess Respiratory 1.04 0.958 – 1.12 0.373 686 7400 exclusion phecode
481 Influenza Respiratory 1.09 0.967 – 1.22 0.166 310 3102 exclusion phecode
483 Acute bronchitis and bronchiolitis Respiratory 1.19 1.02 – 1.39 0.0279 170 1806 exclusion phecode
495 Asthma Respiratory 1.04 1.03 – 1.06 3.82e-10 23495 237944 exclusion phecode
495.2 Asthma with exacerbation Respiratory 1.1 0.954 – 1.26 0.197 218 2384 exclusion phecode
496 Chronic airway obstruction Respiratory 1.05 1.03 – 1.07 1.67e-05 9132 94825 exclusion phecode
496.1 Emphysema Respiratory 1.09 1.04 – 1.15 0.000989 1565 16169 exclusion phecode
496.2 Chronic bronchitis Respiratory 1.06 1.01 – 1.1 0.00828 2544 27371 exclusion phecode
496.21 Obstructive chronic bronchitis Respiratory 1.06 1.02 – 1.11 0.0037 2340 25095 exclusion phecode
496.3 Bronchiectasis Respiratory 0.997 0.949 – 1.05 0.907 1737 17711 exclusion phecode
497 Bronchitis Respiratory 0.928 0.852 – 1.01 0.0897 566 5926 exclusion phecode
500 Lung disease due to external agents Respiratory 1.04 0.93 – 1.15 0.527 360 3774 exclusion phecode
500.1 Extrinsic allergic alveolitis Respiratory 1.01 0.805 – 1.28 0.908 72 730 exclusion phecode
500.2 Pneumoconiosis Respiratory 1.1 0.953 – 1.26 0.198 210 2186 exclusion phecode
501 Pneumonitis due to inhalation of food or vomitus Respiratory 1.06 0.972 – 1.16 0.189 570 6095 exclusion phecode
502 Postinflammatory pulmonary fibrosis Respiratory 1.02 0.95 – 1.1 0.576 803 8485 exclusion phecode
503 Pulmonary congestion and hypostasis Respiratory 1.08 0.976 – 1.2 0.135 387 4746 exclusion phecode
504 Other alveolar and parietoalveolar pneumonopathy Respiratory 1.04 0.926 – 1.18 0.484 287 3065 exclusion phecode
505 Other pulmonary inflamation or edema Respiratory 1.14 0.87 – 1.49 0.34 57 567 exclusion phecode
506 Empyema and pneumothorax Respiratory 1.02 0.957 – 1.09 0.55 1040 10616 exclusion phecode
507 Pleurisy; pleural effusion Respiratory 1 0.973 – 1.03 0.982 5653 60009 exclusion phecode
508
Pulmonary collapse; interstitial and
Pulmonary collapse; interstitial and compensatory emphysema
 Respiratory 0.99 0.944 – 1.04 0.697 1778 18719 exclusion phecode
509 Respiratory failure, insufficiency, arrest Respiratory 1.04 0.996 – 1.09 0.0776 2189 24263 exclusion phecode
509.1 Respiratory failure Respiratory 1.04 0.989 – 1.09 0.126 1740 19285 exclusion phecode
509.2 Respiratory insufficiency Respiratory 1.04 0.984 – 1.09 0.179 1529 16876 exclusion phecode
509.5 Respiratory arrest Respiratory 1.02 0.853 – 1.22 0.829 127 1341 exclusion phecode
509.8
Dependence on respirator [Ventilator] or
Dependence on respirator [Ventilator] or supplemental oxygen
 Respiratory 1.12 0.994 – 1.25 0.0634 316 3606 exclusion phecode
510 Other diseases of lung Respiratory 1.04 0.961 – 1.13 0.325 678 7063 exclusion phecode
512 Other symptoms of respiratory system Respiratory 1.01 0.989 – 1.04 0.298 7972 85020 exclusion phecode
512.1 Wheezing Respiratory 1.01 0.867 – 1.17 0.931 191 2053 exclusion phecode
512.2 Painful respiration Respiratory 1.05 0.906 – 1.21 0.533 199 1962 exclusion phecode
512.7 Shortness of breath Respiratory 1.01 0.982 – 1.04 0.468 5100 55012 exclusion phecode
512.8 Cough Respiratory 1 0.961 – 1.04 0.994 2587 26966 exclusion phecode
512.9 Other dyspnea Respiratory 1.02 0.946 – 1.09 0.637 787 8567 exclusion phecode
513 Respiratory abnormalities Respiratory 1.02 0.932 – 1.11 0.673 522 5717 exclusion phecode
513.3 Hypoventilation Respiratory 0.873 0.677 – 1.12 0.293 57 776 exclusion phecode
513.4 Hyperventilation Respiratory 1.12 0.985 – 1.27 0.0847 252 2633 exclusion phecode
513.8 Disorders of diaphragm Respiratory 0.998 0.838 – 1.19 0.983 134 1427 exclusion phecode
514 Abnormal findings examination of lungs Respiratory 1.02 0.98 – 1.07 0.296 2225 22934 exclusion phecode
516 Abnormal sputum Respiratory 1.02 0.97 – 1.07 0.482 1893 19892 exclusion phecode
516.1 Hemoptysis Respiratory 1.01 0.962 – 1.06 0.701 1838 19364 exclusion phecode
519
Other diseases of respiratory system, not
Other diseases of respiratory system, not elsewhere classified
 Respiratory 1.03 1 – 1.05 0.0225 8205 87976 exclusion phecode
519.2 Respiratory complications Respiratory 1.05 0.935 – 1.19 0.385 287 3066 exclusion phecode
519.8 Other diseases of respiratory system, NEC Respiratory 1.02 1 – 1.05 0.042 7743 83171 exclusion phecode
519.9
Symptoms involving respiratory system and other
Symptoms involving respiratory system and other chest symptoms
 Respiratory 0.988 0.875 – 1.12 0.844 285 2872 exclusion phecode
520 Disorders of tooth development Digestive 0.986 0.941 – 1.03 0.552 1937 19484 exclusion phecode
520.1 Hereditary disturbances in tooth structure Digestive 0.953 0.721 – 1.26 0.737 50 512 exclusion phecode
520.2 Disturbances in tooth eruption Digestive 0.997 0.955 – 1.04 0.885 2249 22566 exclusion phecode
521 Diseases of hard tissues of teeth Digestive 1.02 0.978 – 1.06 0.405 2715 28722 exclusion phecode
521.1 Dental caries Digestive 1.02 0.979 – 1.06 0.356 2724 28828 exclusion phecode
522 Diseases of pulp and periapical tissues Digestive 0.986 0.938 – 1.04 0.594 1665 16910 exclusion phecode
522.5 Periapical abscess Digestive 0.997 0.937 – 1.06 0.933 1089 11171 exclusion phecode
523 Gingival and periodontal diseases Digestive 1.02 0.973 – 1.08 0.354 1574 16027 exclusion phecode
523.1 Gingivitis Digestive 1.06 0.876 – 1.28 0.554 109 1073 exclusion phecode
523.3 Periodontitis (acute or chronic) Digestive 1.04 0.977 – 1.11 0.221 1110 11138 exclusion phecode
523.31 Acute periodontitis Digestive 1.06 0.982 – 1.15 0.131 636 6402 exclusion phecode
523.32 Chronic periodontitis Digestive 1.01 0.925 – 1.11 0.81 534 5310 exclusion phecode
524 Dentofacial anomalies, including malocclusion Digestive 1 0.893 – 1.12 0.98 319 3167 exclusion phecode
524.3 Anomalies of tooth position/malocclusion Digestive 1.03 0.917 – 1.16 0.588 294 2909 exclusion phecode
525
Other diseases of the teeth and supporting
Other diseases of the teeth and supporting structures
 Digestive 0.993 0.953 – 1.04 0.752 2453 25252 exclusion phecode
525.2 Atrophy of edentulous alveolar ridge Digestive 0.918 0.73 – 1.15 0.464 68 675 exclusion phecode
526 Diseases of the jaws Digestive 1.03 0.965 – 1.11 0.341 877 8840 exclusion phecode
526.1 Cysts of the jaws Digestive 1.02 0.909 – 1.15 0.718 306 3125 exclusion phecode
526.3 Anomalies of jaw size/symmetry Digestive 1.11 0.852 – 1.44 0.441 59 588 exclusion phecode
526.4 Temporomandibular joint disorders Digestive 1.04 0.911 – 1.18 0.574 232 2317 exclusion phecode
526.41 Temporomandibular joint disorder, unspecified Digestive 1.06 0.924 – 1.21 0.42 225 2252 exclusion phecode
526.5 Inflammatory conditions of jaw Digestive 0.953 0.78 – 1.16 0.638 101 1048 exclusion phecode
526.9 Jaw disease NOS Digestive 0.996 0.867 – 1.14 0.958 221 2187 exclusion phecode
527 Diseases of the salivary glands Digestive 1.04 0.959 – 1.13 0.338 631 6570 exclusion phecode
527.1 Hypertrophy of salivary gland Digestive 1.22 0.961 – 1.54 0.104 77 790 exclusion phecode
527.2 Sialoadenitis Digestive 1.04 0.933 – 1.17 0.449 331 3475 exclusion phecode
527.7 Disturbance of salivary secretion Digestive 0.833 0.644 – 1.08 0.165 58 585 exclusion phecode
527.8 Other specified diseases of the salivary glands Digestive 1.01 0.829 – 1.22 0.959 114 1130 exclusion phecode
528
Diseases of the oral soft tissues, excluding
Diseases of the oral soft tissues, excluding lesions specific for gingiva and tongue
 Digestive 1.03 0.99 – 1.06 0.158 3592 36647 exclusion phecode
528.1 Stomatitis and mucositis Digestive 1.06 0.957 – 1.17 0.273 426 4417 exclusion phecode
528.11 Stomatitis and mucositis (ulcerative) Digestive 1.1 0.984 – 1.22 0.0971 354 3675 exclusion phecode
528.12 Oral aphthae Digestive 0.927 0.733 – 1.17 0.527 76 795 exclusion phecode
528.3 Cellulitis and abscess of oral soft tissues Digestive 0.959 0.819 – 1.12 0.6 161 1693 exclusion phecode
528.4 Cysts of oral soft tissues Digestive 1.13 0.939 – 1.36 0.195 119 1152 exclusion phecode
528.41 Cyst of the salivary gland Digestive 1.15 0.927 – 1.42 0.207 92 889 exclusion phecode
528.5 Diseases of lips Digestive 1.03 0.948 – 1.11 0.507 648 6442 exclusion phecode
528.6 Leukoplakia of oral mucosa Digestive 1.04 0.92 – 1.17 0.556 282 2915 exclusion phecode
528.7 Sialolithiasis Digestive 0.975 0.863 – 1.1 0.689 288 2949 exclusion phecode
529 Diseases and other conditions of the tongue Digestive 1.02 0.961 – 1.08 0.507 1127 11615 exclusion phecode
529.1 Glossitis Digestive 1.13 1 – 1.28 0.0471 269 2816 exclusion phecode
530 Diseases of esophagus Digestive 1.03 1.02 – 1.04 1.05e-06 30729 264360 exclusion phecode
530.1 Esophagitis, GERD and related diseases Digestive 1.03 1.02 – 1.05 6.16e-08 28746 257848 exclusion phecode
530.11 GERD Digestive 1.03 1.02 – 1.05 2.21e-06 20933 213547 exclusion phecode
530.12 Ulcer of esophagus Digestive 1.05 1.02 – 1.08 0.00146 4732 48651 exclusion phecode
530.14 Reflux esophagitis Digestive 1.04 1.02 – 1.06 0.000118 9652 98531 exclusion phecode
530.2 Esophageal bleeding (varices/hemorrhage) Digestive 0.977 0.926 – 1.03 0.397 1449 15782 exclusion phecode
530.3 Stricture and stenosis of esophagus Digestive 0.991 0.942 – 1.04 0.729 1716 17450 exclusion phecode
530.5 Disorders of esophageal motility Digestive 0.981 0.902 – 1.07 0.655 591 6027 exclusion phecode
530.6 Diverticulum of esophagus, acquired Digestive 0.994 0.84 – 1.18 0.945 141 1432 exclusion phecode
530.7 Gastroesophageal laceration-hemorrhage syndrome Digestive 1.03 0.913 – 1.15 0.663 307 3240 exclusion phecode
530.9 Heartburn Digestive 1.01 0.963 – 1.06 0.717 1963 19749 exclusion phecode
531 Peptic ulcer (excl. esophageal) Digestive 1.04 1.02 – 1.07 0.0014 6334 66470 exclusion phecode
531.1 Hemorrhage from gastrointestinal ulcer Digestive 1.07 0.98 – 1.16 0.135 576 5886 exclusion phecode
531.2 Gastric ulcer Digestive 1.02 0.983 – 1.05 0.322 3616 38404 exclusion phecode
531.3 Duodenal ulcer Digestive 1.08 1.04 – 1.13 6.25e-05 2710 27967 exclusion phecode
531.4 Peptic ulcer, site unspecified Digestive 1.04 0.934 – 1.15 0.495 378 3960 exclusion phecode
532 Dysphagia Digestive 1.02 0.989 – 1.04 0.255 5929 60706 exclusion phecode
535 Gastritis and duodenitis Digestive 1.02 1.01 – 1.04 0.000552 25512 247401 exclusion phecode
535.1 Acute gastritis Digestive 1.11 1.04 – 1.18 0.00158 1043 11095 exclusion phecode
535.2 Atrophic gastritis Digestive 1.02 0.912 – 1.14 0.742 332 3460 exclusion phecode
535.6 Duodenitis Digestive 1.03 1 – 1.05 0.0255 6866 71419 exclusion phecode
535.8 Other specified gastritis Digestive 1.03 1 – 1.05 0.0334 7303 76187 exclusion phecode
535.9 Gastritis and duodenitis, NOS Digestive 1.28 1.05 – 1.57 0.0143 111 1112 exclusion phecode
536.8
Dyspepsia and other specified disorders of
Dyspepsia and other specified disorders of function of stomach
 Digestive 1.07 0.939 – 1.23 0.298 237 2437 exclusion phecode
537 Other disorders of stomach and duodenum Digestive 1.02 0.982 – 1.06 0.323 3017 31937 exclusion phecode
540 Appendiceal conditions Digestive 1.02 0.982 – 1.06 0.313 2946 29333 exclusion phecode
540.1 Appendicitis Digestive 1.02 0.978 – 1.06 0.389 2768 27499 exclusion phecode
540.11 Acute appendicitis Digestive 1.01 0.967 – 1.05 0.706 2486 24685 exclusion phecode
550 Abdominal hernia Digestive 1.01 1 – 1.02 0.00767 42036 267890 exclusion phecode
550.1 Inguinal hernia Digestive 0.993 0.977 – 1.01 0.446 15043 114143 exclusion phecode
550.2 Diaphragmatic hernia Digestive 1.03 1.01 – 1.04 0.000205 24303 225693 exclusion phecode
550.3 Femoral hernia Digestive 0.981 0.904 – 1.06 0.636 643 6178 exclusion phecode
550.4 Umbilical hernia Digestive 0.992 0.957 – 1.03 0.656 3231 34608 exclusion phecode
550.5 Ventral hernia Digestive 1.02 0.982 – 1.06 0.329 3094 32276 exclusion phecode
555
Inflammatory bowel disease and other
Inflammatory bowel disease and other gastroenteritis and colitis
 Digestive 1.03 0.994 – 1.06 0.113 4110 42198 exclusion phecode
555.1 Regional enteritis Digestive 1.08 1.03 – 1.14 0.00312 1615 16508 exclusion phecode
555.2 Ulcerative colitis Digestive 1 0.965 – 1.04 0.886 2925 30119 exclusion phecode
555.21 Ulcerative colitis (chronic) Digestive 0.997 0.91 – 1.09 0.941 500 5102 exclusion phecode
556 Ulceration of the lower GI tract Digestive 1.03 0.97 – 1.1 0.301 980 10066 exclusion phecode
556.1 Ulceration of intestine Digestive 1.03 0.95 – 1.12 0.474 624 6385 exclusion phecode
557 Intestinal malabsorption (non-celiac) Digestive 1.04 0.917 – 1.18 0.555 269 2867 exclusion phecode
557.1 Celiac disease Digestive 1.08 1.03 – 1.13 0.00223 1728 17479 exclusion phecode
558 Noninfectious gastroenteritis Digestive 1.03 1.01 – 1.05 0.00268 13933 147608 exclusion phecode
559 Ileostomy status Digestive 1.01 0.955 – 1.06 0.798 1505 15646 exclusion phecode
560 Intestinal obstruction without mention of hernia Digestive 1.01 0.971 – 1.04 0.772 3625 37175 exclusion phecode
560.1 Paralytic ileus Digestive 1.04 0.948 – 1.14 0.405 475 4886 exclusion phecode
560.2 Impaction of intestine Digestive 0.923 0.81 – 1.05 0.229 245 2535 exclusion phecode
560.3 Peritoneal or intestinal adhesions Digestive 1.02 0.949 – 1.1 0.555 773 7898 exclusion phecode
560.4 Other intestinal obstruction Digestive 1 0.968 – 1.04 0.815 3106 31745 exclusion phecode
561 Symptoms involving digestive system Digestive 1.01 0.996 – 1.03 0.126 14628 150168 exclusion phecode
561.1 Diarrhea Digestive 0.946 0.857 – 1.04 0.268 442 4407 exclusion phecode
561.2 Flatulence Digestive 1 0.951 – 1.05 0.956 1577 16031 exclusion phecode
562 Diverticulosis and diverticulitis Digestive 1.03 1.02 – 1.04 2.92e-05 24336 200327 exclusion phecode
562.1 Diverticulosis Digestive 1.03 1.02 – 1.04 2.94e-05 24304 200278 exclusion phecode
563 Constipation Digestive 1 0.984 – 1.03 0.665 9388 97782 exclusion phecode
564 Functional digestive disorders Digestive 1.03 1.02 – 1.05 1.37e-05 19892 199204 exclusion phecode
564.1 Irritable Bowel Syndrome Digestive 1.04 1.02 – 1.08 0.00282 5125 52788 exclusion phecode
564.8
Abnormal findings on exam of gastrointestinal
Abnormal findings on exam of gastrointestinal tract/ abdominal area
 Digestive 1.04 0.987 – 1.1 0.145 1506 15594 exclusion phecode
564.9 Personal history of diseases of digestive system Digestive 1.03 1.02 – 1.05 0.000226 13876 143160 exclusion phecode
565 Anal and rectal conditions Digestive 1.02 1 – 1.04 0.0168 13575 138890 exclusion phecode
565.1 Anal and rectal polyp Digestive 1.02 0.997 – 1.05 0.0846 6731 68946 exclusion phecode
567 Peritonitis and retroperitoneal infections Digestive 1 0.935 – 1.08 0.907 807 8736 exclusion phecode
568 Other disorders of peritoneum Digestive 1.02 0.981 – 1.06 0.33 3010 30910 exclusion phecode
568.1
Peritoneal adhesions (postoperative)
Peritoneal adhesions (postoperative) (postinfection)
 Digestive 1.02 0.985 – 1.06 0.235 2863 29370 exclusion phecode
569 Other disorders of intestine Digestive 1.03 0.995 – 1.06 0.101 3781 39469 exclusion phecode
569.1 Toxic gastroenteritis and colitis Digestive 1.08 0.902 – 1.28 0.413 130 1387 exclusion phecode
569.2 Gastrointestinal complications Digestive 1.01 0.922 – 1.12 0.768 452 4552 exclusion phecode
571 Chronic liver disease and cirrhosis Digestive 1.07 1.03 – 1.12 0.00184 2298 27875 exclusion phecode
571.5 Other chronic nonalcoholic liver disease Digestive 1.15 1.08 – 1.21 2.66e-06 1276 15957 exclusion phecode
571.51 Cirrhosis of liver without mention of alcohol Digestive 1.28 1.03 – 1.59 0.026 85 1064 exclusion phecode
571.6 Primary biliary cirrhosis Digestive 0.953 0.836 – 1.09 0.478 235 2450 exclusion phecode
571.8
Liver abscess and sequelae of chronic liver
Liver abscess and sequelae of chronic liver disease
 Digestive 0.968 0.899 – 1.04 0.394 752 9194 exclusion phecode
571.81 Portal hypertension Digestive 0.958 0.864 – 1.06 0.419 380 4962 exclusion phecode
572 Ascites (non malignant) Digestive 1.05 0.994 – 1.11 0.08 1327 14521 exclusion phecode
573 Other disorders of liver Digestive 0.954 0.902 – 1.01 0.0948 1341 14109 exclusion phecode
573.2 Liver replaced by transplant Digestive 1.08 0.864 – 1.36 0.489 72 901 exclusion phecode
573.3 Hepatomegaly Digestive 1.04 0.916 – 1.19 0.528 244 2785 exclusion phecode
573.5 Jaundice (not of newborn) Digestive 1.03 0.959 – 1.11 0.399 798 8392 exclusion phecode
573.7 Abnormal results of function study of liver Digestive 1.06 1.02 – 1.1 0.00119 3027 32618 exclusion phecode
573.9 Abnormal serum enzyme levels Digestive 0.959 0.822 – 1.12 0.589 182 1938 exclusion phecode
574 Cholelithiasis and cholecystitis Digestive 1.07 1.05 – 1.08 3.43e-13 14237 148220 exclusion phecode
574.1 Cholelithiasis Digestive 1.06 1.04 – 1.08 4.15e-11 12362 128746 exclusion phecode
574.11 Cholelithiasis with acute cholecystitis Digestive 1.1 1.04 – 1.17 0.000513 1362 14233 exclusion phecode
574.12 Cholelithiasis with other cholecystitis Digestive 1.05 1.02 – 1.08 0.000591 4994 51608 exclusion phecode
574.2 Calculus of bile duct Digestive 1.04 0.997 – 1.08 0.0698 2397 24744 exclusion phecode
574.3 Cholecystitis without cholelithiasis Digestive 1.11 1.06 – 1.15 2.2e-06 2453 26038 exclusion phecode
575 Other biliary tract disease Digestive 1.04 1 – 1.07 0.0385 3517 36487 exclusion phecode
575.1 Cholangitis Digestive 1.05 0.954 – 1.16 0.31 439 4584 exclusion phecode
575.2 Obstruction of bile duct Digestive 0.952 0.88 – 1.03 0.222 687 7223 exclusion phecode
575.6 Cholesterolosis of gallbladder Digestive 1.16 1.05 – 1.28 0.0036 429 4368 exclusion phecode
575.7 Other disorders of gallbladder Digestive 1.04 0.979 – 1.1 0.212 1296 13362 exclusion phecode
575.8 Other disorders of biliary tract Digestive 1.01 0.942 – 1.08 0.82 937 9770 exclusion phecode
575.9
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of biliary tract
 Digestive 0.997 0.89 – 1.12 0.954 311 3264 exclusion phecode
577 Diseases of pancreas Digestive 1.08 1.04 – 1.13 0.000196 2318 25039 exclusion phecode
577.1 Acute pancreatitis Digestive 1.1 1.05 – 1.15 0.000135 1749 18760 exclusion phecode
577.2 Chronic pancreatitis Digestive 1.08 0.972 – 1.19 0.156 402 4821 exclusion phecode
577.3 Cyst and pseudocyst of pancreas Digestive 1.14 1.01 – 1.28 0.0297 306 3419 exclusion phecode
578 Gastrointestinal hemorrhage Digestive 1.01 0.994 – 1.02 0.25 19004 194935 exclusion phecode
578.1 Hematemesis Digestive 1.03 0.983 – 1.09 0.199 1710 18403 exclusion phecode
578.2 Blood in stool Digestive 1.03 0.984 – 1.07 0.222 2348 24635 exclusion phecode
578.8 Hemorrhage of rectum and anus Digestive 1.01 0.991 – 1.03 0.292 12141 123882 exclusion phecode
578.9 Hemorrhage of gastrointestinal tract Digestive 0.99 0.961 – 1.02 0.51 4852 49810 exclusion phecode
579 Other symptoms involving abdomen and pelvis Digestive 0.991 0.937 – 1.05 0.759 1360 14667 exclusion phecode
579.2 Splenomegaly Digestive 0.963 0.86 – 1.08 0.509 332 3963 exclusion phecode
579.8 Nonspecific abnormal findings in stool contents Digestive 0.996 0.944 – 1.05 0.87 1505 15642 exclusion phecode
580 Nephritis; nephrosis; renal sclerosis Genitourinary 1.02 0.96 – 1.09 0.494 1062 14380 exclusion phecode
580.1 Glomerulonephritis Genitourinary 1.06 0.987 – 1.14 0.109 790 9865 exclusion phecode
580.11 Proliferative glomerulonephritis Genitourinary 0.974 0.759 – 1.25 0.837 65 695 exclusion phecode
580.12 Non-proliferative glomerulonephritis Genitourinary 0.978 0.809 – 1.18 0.816 120 1288 exclusion phecode
580.14 Chronic glomerulonephritis, NOS Genitourinary 1.06 0.982 – 1.15 0.129 634 8183 exclusion phecode
580.2
Nephrotic syndrome without mention of
Nephrotic syndrome without mention of glomerulonephritis
 Genitourinary 0.899 0.787 – 1.03 0.114 227 4397 exclusion phecode
580.3
Nephritis and nephropathy without mention of
Nephritis and nephropathy without mention of glomerulonephritis
 Genitourinary 1.05 0.917 – 1.21 0.469 204 2328 exclusion phecode
580.32
Nephritis and nephropathy with pathological
Nephritis and nephropathy with pathological lesion
 Genitourinary 1.04 0.905 – 1.19 0.601 207 2397 exclusion phecode
585 Renal failure Genitourinary 1.02 0.995 – 1.05 0.111 5425 64995 exclusion phecode
585.1 Acute renal failure Genitourinary 1.01 0.979 – 1.05 0.433 3464 42142 exclusion phecode
585.2 Renal failure NOS Genitourinary 0.979 0.922 – 1.04 0.48 1172 13634 exclusion phecode
585.3 Chronic renal failure [CKD] Genitourinary 1.06 1.01 – 1.11 0.0206 1923 24661 exclusion phecode
585.31 Renal dialysis Genitourinary 0.993 0.896 – 1.1 0.894 380 4640 exclusion phecode
586 Other disorders of the kidney and ureters Genitourinary 1.01 0.972 – 1.05 0.638 2972 31547 exclusion phecode
586.1 Anatomical abnormatilies of kidney and ureters Genitourinary 0.973 0.836 – 1.13 0.719 185 1974 exclusion phecode
586.11 Small kidney Genitourinary 0.985 0.836 – 1.16 0.855 157 1701 exclusion phecode
586.2 Cyst of kidney, acquired Genitourinary 0.966 0.909 – 1.03 0.26 1135 11756 exclusion phecode
586.3 Vascular disorders of kidney/hypertrophy Genitourinary 0.991 0.777 – 1.26 0.942 70 747 exclusion phecode
586.4 Stricture/obstruction of ureter Genitourinary 1.09 1.01 – 1.17 0.0241 818 8584 exclusion phecode
587 Kidney replaced by transpant Genitourinary 1 0.892 – 1.12 0.982 307 3498 exclusion phecode
588 Disorders resulting from impaired renal function Genitourinary 1.03 0.821 – 1.29 0.809 78 923 exclusion phecode
589 Abnormal results of function study of kidney Genitourinary 0.853 0.697 – 1.05 0.126 94 1096 exclusion phecode
590 Pyelonephritis Genitourinary 1.08 1.01 – 1.14 0.0177 1180 12664 exclusion phecode
591 Urinary tract infection Genitourinary 1.01 0.995 – 1.04 0.14 10956 116943 exclusion phecode
592 Cystitis and urethritis Genitourinary 1.02 0.978 – 1.06 0.403 2703 28064 exclusion phecode
592.1 Cystitis Genitourinary 1.02 0.978 – 1.06 0.382 2647 27483 exclusion phecode
592.11 Acute cystitis Genitourinary 0.869 0.722 – 1.04 0.135 127 1288 exclusion phecode
592.12 Chronic cystitis Genitourinary 1.08 1.01 – 1.16 0.0302 809 8385 exclusion phecode
592.13 Chronic interstitial cystitis Genitourinary 0.938 0.822 – 1.07 0.346 234 2359 exclusion phecode
592.2 Urethritis and urethral syndrome Genitourinary 1.08 0.92 – 1.27 0.344 152 1577 exclusion phecode
593 Hematuria Genitourinary 1.02 1 – 1.04 0.0407 14660 150490 exclusion phecode
594 Urinary calculus Genitourinary 1.06 1.04 – 1.09 8.8e-06 5637 59787 exclusion phecode
594.1 Calculus of kidney Genitourinary 1.05 1.01 – 1.09 0.0154 2770 29764 exclusion phecode
594.2 Calculus of lower urinary tract Genitourinary 1.04 0.965 – 1.13 0.285 676 7198 exclusion phecode
594.3 Calculus of ureter Genitourinary 1.06 1.01 – 1.11 0.00943 2104 22472 exclusion phecode
594.8 Renal colic Genitourinary 1.08 1.03 – 1.13 0.00229 1830 19298 exclusion phecode
595 Hydronephrosis Genitourinary 1.01 0.965 – 1.07 0.59 1708 18144 exclusion phecode
596 Other disorders of bladder Genitourinary 1.01 0.99 – 1.03 0.282 8894 91056 exclusion phecode
596.1 Bladder neck obstruction Genitourinary 1.04 0.986 – 1.09 0.163 1785 18071 exclusion phecode
596.5 Functional disorders of bladder Genitourinary 1.02 0.966 – 1.07 0.51 1505 15631 exclusion phecode
597 Other disorders of urethra and urinary tract Genitourinary 1.02 0.984 – 1.05 0.31 3558 36701 exclusion phecode
597.1 Urethral stricture (not specified as infectious) Genitourinary 1.02 0.98 – 1.06 0.37 3002 31026 exclusion phecode
597.2 Urinary complications NEC Genitourinary 0.998 0.785 – 1.27 0.989 67 728 exclusion phecode
598 Abnormal findings on examination of urine Genitourinary 0.977 0.942 – 1.01 0.21 3201 32890 exclusion phecode
598.9
Other nonspecific findings on examination of
Other nonspecific findings on examination of urine
 Genitourinary 0.904 0.798 – 1.02 0.113 270 2848 exclusion phecode
599 Other symptoms/disorders or the urinary system Genitourinary 1.01 0.998 – 1.03 0.0909 16879 174093 exclusion phecode
599.1 Urinary obstruction Genitourinary 0.907 0.763 – 1.08 0.268 141 1543 exclusion phecode
599.2 Retention of urine Genitourinary 1.01 0.988 – 1.04 0.273 6033 62088 exclusion phecode
599.3 Dysuria Genitourinary 0.992 0.933 – 1.06 0.81 1082 11281 exclusion phecode
599.4 Urinary incontinence Genitourinary 1.01 0.982 – 1.03 0.666 8118 83676 exclusion phecode
599.5 Frequency of urination and polyuria Genitourinary 0.991 0.958 – 1.02 0.588 3641 37653 exclusion phecode
599.6 Oliguria and anuria Genitourinary 1.09 0.88 – 1.35 0.428 84 989 exclusion phecode
599.8 Other symptoms involving urinary system Genitourinary 1.16 0.887 – 1.51 0.28 60 577 exclusion phecode
599.9 Other abnormality of urination Genitourinary 0.983 0.936 – 1.03 0.494 1726 17873 exclusion phecode
600 Hyperplasia of prostate Genitourinary 1 0.983 – 1.03 0.702 9996 80373 exclusion phecode
601 Inflammatory diseases of prostate Genitourinary 1 0.956 – 1.05 0.905 1876 19115 exclusion phecode
601.1 Prostatitis Genitourinary 1.01 0.958 – 1.07 0.677 1456 14346 exclusion phecode
601.11 Acute prostatitis Genitourinary 0.947 0.823 – 1.09 0.447 214 2159 exclusion phecode
601.12 Chronic prostatitis Genitourinary 0.954 0.888 – 1.03 0.203 838 8250 exclusion phecode
601.3 Orchitis and epididymitis Genitourinary 1.11 0.851 – 1.45 0.439 55 543 exclusion phecode
601.4 Balanoposthitis Genitourinary 0.978 0.858 – 1.12 0.743 227 2628 exclusion phecode
601.8
Other inflammatory disorders of male genital
Other inflammatory disorders of male genital organs
 Genitourinary 0.998 0.878 – 1.13 0.977 259 2786 exclusion phecode
602 Other disorders of prostate Genitourinary 1.02 0.959 – 1.08 0.559 1216 12179 exclusion phecode
603 Other disorders of testis Genitourinary 1.06 1.01 – 1.11 0.0107 1921 19960 exclusion phecode
603.1 Hydrocele Genitourinary 1.04 0.978 – 1.1 0.22 1197 12347 exclusion phecode
604 Disorders of penis Genitourinary 1.01 0.973 – 1.05 0.567 2786 30489 exclusion phecode
604.1 Redundant prepuce and phimosis/BXO Genitourinary 0.994 0.952 – 1.04 0.769 2287 25254 exclusion phecode
605 Erectile dysfunction [ED] Genitourinary 1.17 1.02 – 1.34 0.0238 222 2516 exclusion phecode
608 Other disorders of male genital organs Genitourinary 1 0.964 – 1.04 0.872 2616 26196 exclusion phecode
609 Male infertility and abnormal spermatozoa Genitourinary 1.01 0.875 – 1.18 0.849 190 1955 exclusion phecode
609.1 Infertility, male Genitourinary 0.987 0.758 – 1.29 0.922 57 604 exclusion phecode
609.2 Abnormal spermatozoa Genitourinary 1.05 0.891 – 1.24 0.559 149 1527 exclusion phecode
610 Benign mammary dysplasias Genitourinary 0.981 0.941 – 1.02 0.378 2382 23939 exclusion phecode
610.1 Cystic mastopathy Genitourinary 0.965 0.901 – 1.03 0.301 886 8911 exclusion phecode
610.2 Fibroadenosis of breast Genitourinary 1.11 0.987 – 1.25 0.0813 293 2939 exclusion phecode
610.3 Fibrosclerosis of breast Genitourinary 1.04 0.922 – 1.18 0.517 292 2908 exclusion phecode
610.4 Benign neoplasm of breast Genitourinary 0.961 0.91 – 1.02 0.166 1341 13391 exclusion phecode
610.8 Other specified benign mammary dysplasias Genitourinary 1 0.924 – 1.09 0.951 648 6695 exclusion phecode
611 Abnormal findings on mammogram or breast exam Genitourinary 1.02 0.97 – 1.08 0.418 1509 15151 exclusion phecode
611.1 Abnormal mammogram Genitourinary 1.41 1.07 – 1.87 0.0152 56 543 exclusion phecode
611.3 Lump or mass in breast Genitourinary 1.02 0.964 – 1.07 0.542 1458 14671 exclusion phecode
612
Breast conditions, congenital or relating to
Breast conditions, congenital or relating to hormones
 Genitourinary 1.03 0.964 – 1.11 0.345 834 8530 exclusion phecode
612.2 Hypertrophy of breast (Gynecomastia) Genitourinary 1.03 0.955 – 1.1 0.477 792 8135 exclusion phecode
612.3 Congenital anomalies of breast Genitourinary 1.08 0.85 – 1.36 0.541 72 702 exclusion phecode
613 Other nonmalignant breast conditions Genitourinary 1 0.953 – 1.06 0.876 1562 15868 exclusion phecode
613.1 Inflammatory disease of breast Genitourinary 1.08 0.997 – 1.17 0.0583 681 6902 exclusion phecode
613.5 Mastodynia Genitourinary 0.909 0.714 – 1.16 0.435 71 740 exclusion phecode
613.7 Other signs and symptoms in breast Genitourinary 0.976 0.902 – 1.06 0.54 674 6734 exclusion phecode
613.8 Other specified disorders of breast Genitourinary 1 0.894 – 1.13 0.937 308 3153 exclusion phecode
613.9 Breast disorder NOS Genitourinary 0.928 0.802 – 1.07 0.316 195 1993 exclusion phecode
614 Inflammatory diseases of female pelvic organs Genitourinary 1.03 1.01 – 1.06 0.0176 5440 55217 exclusion phecode
614.1
Pelvic peritoneal adhesions, female
Pelvic peritoneal adhesions, female (postoperative) (postinfection)
 Genitourinary 1.05 1.01 – 1.1 0.0222 2415 24562 exclusion phecode
614.3 Pelvic inflammatory disease (PID) Genitourinary 1.02 0.944 – 1.09 0.67 786 8054 exclusion phecode
614.31 Acute inflammatory pelvic disease Genitourinary 1.16 0.898 – 1.5 0.256 58 589 exclusion phecode
614.32 Chronic inflammatory pelvic disease Genitourinary 1.03 0.928 – 1.14 0.592 401 4085 exclusion phecode
614.33 Pelvic inflammatory disease, NOS Genitourinary 1.03 0.917 – 1.15 0.638 331 3406 exclusion phecode
614.4 Inflammatory diseases of uterus, except cervix Genitourinary 1.17 1.03 – 1.33 0.0152 260 2681 exclusion phecode
614.5
Inflammatory disease of cervix, vagina, and
Inflammatory disease of cervix, vagina, and vulva
 Genitourinary 1.03 0.987 – 1.07 0.178 2489 25106 exclusion phecode
614.51 Cervicitis and endocervicitis Genitourinary 1 0.948 – 1.06 0.868 1273 12705 exclusion phecode
614.52 Vaginitis and vulvovaginitis Genitourinary 0.992 0.894 – 1.1 0.879 400 4104 exclusion phecode
614.53 Cyst or abscess of Bartholin's gland Genitourinary 1.04 0.964 – 1.12 0.314 738 7335 exclusion phecode
614.54 Abscess or ulceration of vulva Genitourinary 1.17 1.03 – 1.34 0.0165 239 2637 exclusion phecode
615 Endometriosis Genitourinary 1.04 1.01 – 1.08 0.0183 3889 39090 exclusion phecode
617
Disorders secondary to childbirth, surgery
Disorders secondary to childbirth, surgery, trauma
 Genitourinary 1.14 1.01 – 1.29 0.0382 282 2913 exclusion phecode
618 Genital prolapse Genitourinary 1.05 1.02 – 1.07 9.4e-06 11118 112036 exclusion phecode
618.1 Prolapse of vaginal walls Genitourinary 1.04 1.01 – 1.06 0.00424 7003 70837 exclusion phecode
618.2 Uterine/Uterovaginal prolapse Genitourinary 1.06 1.03 – 1.09 6.23e-05 5155 51655 exclusion phecode
618.5 Prolapse of vaginal vault after hysterectomy Genitourinary 1.09 0.991 – 1.2 0.075 486 4904 exclusion phecode
618.6 Vaginal enterocele, congenital or acquired Genitourinary 1.02 0.945 – 1.11 0.567 644 6499 exclusion phecode
619 Noninflammatory female genital disorders Genitourinary 1.03 1.01 – 1.05 0.0105 8363 84184 exclusion phecode
619.1
Noninflammatory disorders of ovary, fallopian
Noninflammatory disorders of ovary, fallopian tube, and broad ligament
 Genitourinary 1.02 0.946 – 1.1 0.584 693 7033 exclusion phecode
619.2 Disorders of uterus, NEC Genitourinary 1.04 1.01 – 1.08 0.0207 3193 32009 exclusion phecode
619.3 Noninflammatory disorders of cervix Genitourinary 1.02 0.983 – 1.06 0.259 2749 27642 exclusion phecode
619.4 Noninflammatory disorders of vagina Genitourinary 0.984 0.936 – 1.03 0.536 1677 17029 exclusion phecode
619.5 Noninflammatory disorders of vulva and perineum Genitourinary 1.05 0.988 – 1.11 0.123 1300 13027 exclusion phecode
620 Dysplasia of female genital organs Genitourinary 1.18 0.935 – 1.49 0.162 69 696 exclusion phecode
621 Endometrial hyperplasia Genitourinary 1.04 0.976 – 1.11 0.228 1039 10848 exclusion phecode
622 Polyp of female genital organs Genitourinary 1.02 0.999 – 1.04 0.0608 9968 100916 exclusion phecode
622.1 Polyp of corpus uteri Genitourinary 1.02 0.999 – 1.05 0.0623 7440 75629 exclusion phecode
622.2 Mucous polyp of cervix Genitourinary 1 0.964 – 1.04 0.98 3310 33101 exclusion phecode
623 Hypertrophy of female genital organs Genitourinary 1.01 0.956 – 1.08 0.651 1206 12258 exclusion phecode
624 Symptoms involving female genital tract Genitourinary 1.04 0.964 – 1.12 0.323 763 7635 exclusion phecode
624.1 Dystrophy of female genital tract Genitourinary 1.11 0.967 – 1.28 0.137 223 2263 exclusion phecode
624.2 Atrophy of female genital tract Genitourinary 0.993 0.897 – 1.1 0.891 424 4232 exclusion phecode
624.9 stress incontinence, female Genitourinary 1.04 1.01 – 1.07 0.00552 5523 56453 exclusion phecode
625
Pain and other symptoms associated with female
Pain and other symptoms associated with female genital organs
 Genitourinary 1.02 0.981 – 1.06 0.329 2785 27865 exclusion phecode
625.1 Dyspareunia Genitourinary 1.02 0.958 – 1.08 0.556 1145 11517 exclusion phecode
626
Disorders of menstruation and other abnormal
Disorders of menstruation and other abnormal bleeding from female genital tract
 Genitourinary 1.02 1.01 – 1.04 0.00589 15528 111487 exclusion phecode
626.1 Irregular menstrual cycle/bleeding Genitourinary 1.03 1.01 – 1.05 0.0035 13545 106593 exclusion phecode
626.11 Absent or infrequent menstruation Genitourinary 0.886 0.727 – 1.08 0.226 104 1065 exclusion phecode
626.12 Excessive or frequent menstruation Genitourinary 1.04 1.01 – 1.06 0.00138 9300 88996 exclusion phecode
626.13 Irregular menstrual cycle Genitourinary 0.984 0.939 – 1.03 0.492 1893 19168 exclusion phecode
626.14 Irregular menstrual bleeding Genitourinary 1.04 1.01 – 1.08 0.0216 3672 36941 exclusion phecode
626.2 Dysmenorrhea Genitourinary 1.04 0.988 – 1.09 0.137 1699 17257 exclusion phecode
626.4 Premenstrual tension syndromes Genitourinary 1 0.847 – 1.19 0.981 156 1546 exclusion phecode
626.8 Infertility, female Genitourinary 1.02 0.964 – 1.08 0.493 1330 13255 exclusion phecode
627 Menopausal and postmenopausal disorders Genitourinary 1.03 1.01 – 1.05 0.00622 9793 99738 exclusion phecode
627.1 Postmenopausal bleeding Genitourinary 1.03 1.01 – 1.05 0.007 8516 86721 exclusion phecode
627.2 Symptomatic menopause Genitourinary 1.09 0.933 – 1.27 0.282 176 1772 exclusion phecode
627.3 Postmenopausal atrophic vaginitis Genitourinary 1.02 0.958 – 1.09 0.534 1065 10660 exclusion phecode
627.4 Premenopausal menorrhagia Genitourinary 1.01 0.897 – 1.14 0.859 289 2989 exclusion phecode
628 Ovarian cyst Genitourinary 1.02 0.993 – 1.06 0.125 4542 45955 exclusion phecode
634 Miscarriage; stillbirth Pregnancy Complications 0.971 0.943 – 1 0.0495 5105 35607 exclusion phecode
634.1 Missed abortion/Hydatidiform mole Pregnancy Complications 0.983 0.925 – 1.05 0.589 1111 11073 exclusion phecode
634.3 Ectopic pregnancy Pregnancy Complications 1.03 0.917 – 1.15 0.664 324 3241 exclusion phecode
635
Hemorrhage during pregnancy; childbirth and
Hemorrhage during pregnancy; childbirth and postpartum
 Pregnancy Complications 0.967 0.923 – 1.01 0.162 1922 17014 exclusion phecode
635.2
Antepartum hemorrhage, abruptio placentae, and
Antepartum hemorrhage, abruptio placentae, and placenta previa
 Pregnancy Complications 0.959 0.893 – 1.03 0.24 848 8440 exclusion phecode
635.3 Placenta previa and abruptio placenta Pregnancy Complications 0.962 0.907 – 1.02 0.193 1234 12059 exclusion phecode
636
Early or threatened labor; hemorrhage in early
Early or threatened labor; hemorrhage in early pregnancy
 Pregnancy Complications 1.02 0.973 – 1.06 0.467 2286 19568 exclusion phecode
636.2 Early onset of delivery Pregnancy Complications 1.02 0.936 – 1.11 0.674 593 6017 exclusion phecode
636.3 Hemorrhage in early pregnancy Pregnancy Complications 1.03 0.968 – 1.1 0.35 1049 10542 exclusion phecode
638 Other high-risk pregnancy Pregnancy Complications 1.06 0.83 – 1.36 0.625 67 686 exclusion phecode
642
Hypertension complicating pregnancy
Hypertension complicating pregnancy, childbirth, and the puerperium
 Pregnancy Complications 1.01 0.947 – 1.07 0.791 1053 10847 exclusion phecode
642.1 Preeclampsia and eclampsia Pregnancy Complications 1.02 0.907 – 1.15 0.727 289 2990 exclusion phecode
643 Excessive vomiting in pregnancy Pregnancy Complications 0.983 0.847 – 1.14 0.827 203 2106 exclusion phecode
643.1 Hyperemesis gravidarum Pregnancy Complications 0.96 0.806 – 1.14 0.651 145 1496 exclusion phecode
645 Late pregnancy and failed induction Pregnancy Complications 0.96 0.905 – 1.02 0.178 1221 12220 exclusion phecode
646 Other complications of pregnancy NEC Pregnancy Complications 0.988 0.945 – 1.03 0.599 2148 20439 exclusion phecode
647
Infectious and parasitic complications
Infectious and parasitic complications affecting pregnancy
 Pregnancy Complications 1.43 1.1 – 1.87 0.00765 68 663 exclusion phecode
647.1
Infections of genitourinary tract during
Infections of genitourinary tract during pregnancy
 Pregnancy Complications 0.94 0.83 – 1.06 0.332 268 2698 exclusion phecode
649
Other conditions or status of the mother
Other conditions or status of the mother complicating pregnancy, childbirth, or the puerperium
 Pregnancy Complications 0.939 0.768 – 1.15 0.538 107 1112 exclusion phecode
649.1
Diabetes or abnormal glucose tolerance
Diabetes or abnormal glucose tolerance complicating pregnancy
 Pregnancy Complications 0.977 0.741 – 1.29 0.867 50 1891 exclusion phecode
650 Normal delivery Pregnancy Complications 0.948 0.904 – 0.994 0.026 1892 18558 exclusion phecode
651 Multiple gestation Pregnancy Complications 0.973 0.87 – 1.09 0.632 338 3390 exclusion phecode
652
Malposition and malpresentation of fetus or
Malposition and malpresentation of fetus or obstruction
 Pregnancy Complications 0.966 0.918 – 1.02 0.173 1675 16191 exclusion phecode
653
Problems associated with amniotic cavity and
Problems associated with amniotic cavity and membranes
 Pregnancy Complications 0.976 0.923 – 1.03 0.391 1371 13371 exclusion phecode
654
Other and unspecified complications of birth
Other and unspecified complications of birth; puerperium affecting management of mother
 Pregnancy Complications 1.03 0.816 – 1.3 0.803 72 727 exclusion phecode
655
Known or suspected fetal abnormality affecting
Known or suspected fetal abnormality affecting management of mother
 Pregnancy Complications 0.968 0.937 – 1 0.0492 4192 28851 exclusion phecode
656 Other perinatal conditions of fetus or newborn Pregnancy Complications 1.03 0.847 – 1.25 0.764 105 1051 exclusion phecode
661 Fetal distress and abnormal forces of labor Pregnancy Complications 0.984 0.941 – 1.03 0.477 2210 18007 exclusion phecode
663
Umbilical cord complications during labor and
Umbilical cord complications during labor and delivery
 Pregnancy Complications 1.04 0.949 – 1.13 0.415 517 5194 exclusion phecode
665 Obstetrical/birth trauma Pregnancy Complications 0.962 0.934 – 0.991 0.0114 5235 28815 exclusion phecode
669 Complications of labor and delivery NEC Pregnancy Complications 0.961 0.922 – 1 0.0617 2502 20734 exclusion phecode
671
Venous/cerebrovascular complications embolism
Venous/cerebrovascular complications embolism in pregnancy and the puerperium
 Pregnancy Complications 1 0.857 – 1.18 0.957 158 1586 exclusion phecode
674 Other complications of the puerperium NEC Pregnancy Complications 1.16 1.02 – 1.32 0.0254 251 2547 exclusion phecode
676
Other disorders of the breast associated with
Other disorders of the breast associated with childbirth and disorders of lactation
 Pregnancy Complications 0.914 0.702 – 1.19 0.504 63 609 exclusion phecode
679 Complications of in utero procedures Dermatologic 0.878 0.664 – 1.16 0.361 51 514 exclusion phecode
681 Superficial cellulitis and abscess Dermatologic 0.98 0.954 – 1.01 0.126 6104 67994 exclusion phecode
681.1 Cellulitis and abscess of fingers/toes Dermatologic 0.992 0.903 – 1.09 0.875 473 5322 exclusion phecode
681.2 Cellulitis and abscess of face/neck Dermatologic 1.04 0.943 – 1.14 0.457 474 4941 exclusion phecode
681.3 Cellulitis and abscess of arm/hand Dermatologic 0.962 0.934 – 0.992 0.0132 4576 51689 exclusion phecode
681.5 Cellulitis and abscess of leg, except foot Dermatologic 0.964 0.936 – 0.994 0.0194 4581 51745 exclusion phecode
681.6 Cellulitis and abscess of foot, toe Dermatologic 0.963 0.934 – 0.993 0.016 4541 51336 exclusion phecode
681.7 Cellulitis and abscess of trunk Dermatologic 1.01 0.924 – 1.11 0.819 524 5692 exclusion phecode
686
Other local infections of skin and subcutaneous
Other local infections of skin and subcutaneous tissue
 Dermatologic 1.03 0.967 – 1.09 0.376 1124 12646 exclusion phecode
686.1 Carbuncle and furuncle Dermatologic 0.978 0.934 – 1.02 0.345 1948 21676 exclusion phecode
686.3 Pilonidal cyst Dermatologic 1.02 0.937 – 1.12 0.595 524 5552 exclusion phecode
686.4 Pyogenic granuloma Dermatologic 1.06 0.94 – 1.19 0.356 328 3429 exclusion phecode
687 Symptoms affecting skin Dermatologic 0.964 0.879 – 1.06 0.431 498 5216 exclusion phecode
687.1 Rash and other nonspecific skin eruption Dermatologic 0.941 0.898 – 0.986 0.0103 1945 20296 exclusion phecode
687.2 Localized superficial swelling, mass, or lump Dermatologic 1.01 0.893 – 1.15 0.858 264 2692 exclusion phecode
687.3 Changes in skin texture Dermatologic 0.827 0.679 – 1.01 0.0594 103 1007 exclusion phecode
687.4 Disturbance of skin sensation Dermatologic 1.02 0.976 – 1.06 0.429 2637 27337 exclusion phecode
689 Disorder of skin and subcutaneous tissue NOS Dermatologic 1.02 0.989 – 1.05 0.243 5340 54233 exclusion phecode
690 Erythematosquamous dermatosis Dermatologic 0.828 0.641 – 1.07 0.15 63 652 exclusion phecode
690.1 Seborrheic dermatitis Dermatologic 0.705 0.519 – 0.958 0.0255 46 494 exclusion phecode
691 Congenital anomalies of skin Dermatologic 1 0.833 – 1.21 0.968 112 1120 exclusion phecode
694 Dyschromia and Vitiligo Dermatologic 1.01 0.946 – 1.08 0.729 924 9323 exclusion phecode
694.1 Vitiligo Dermatologic 1.02 0.77 – 1.35 0.894 52 567 exclusion phecode
694.2 Other dyschromia Dermatologic 1.04 0.96 – 1.12 0.368 748 7415 exclusion phecode
694.3 Vascular disorders of skin Dermatologic 0.89 0.728 – 1.09 0.257 99 1104 exclusion phecode
695 Erythematous conditions Dermatologic 1.06 1.01 – 1.11 0.011 2170 22502 exclusion phecode
695.1 Toxic erythema Dermatologic 0.971 0.799 – 1.18 0.77 102 1042 exclusion phecode
695.2 Bullous dermatoses Dermatologic 1.05 0.866 – 1.27 0.633 121 1271 exclusion phecode
695.21 Dermatitis herpetiformis Dermatologic 0.995 0.746 – 1.33 0.973 51 526 exclusion phecode
695.22 Pemphigus and pemphigoid Dermatologic 0.956 0.739 – 1.24 0.731 64 682 exclusion phecode
695.3 Rosacea Dermatologic 1.19 1.05 – 1.35 0.00542 283 2885 exclusion phecode
695.4 Lupus (localized and systemic) Dermatologic 0.974 0.878 – 1.08 0.624 391 3938 exclusion phecode
695.41 Cutaneous lupus erythematosus Dermatologic 0.838 0.699 – 1.01 0.058 124 1232 exclusion phecode
695.42 Systemic lupus erythematosus Dermatologic 1.02 0.908 – 1.14 0.761 323 3265 exclusion phecode
695.7 Prurigo and Lichen Dermatologic 1.07 0.99 – 1.15 0.0896 706 7357 exclusion phecode
695.8 Other specified erythematous conditions Dermatologic 1.21 1.05 – 1.4 0.00755 210 2244 exclusion phecode
695.81 Erythema nodosum Dermatologic 1.23 0.965 – 1.57 0.0953 71 730 exclusion phecode
695.9 Unspecified erythematous condition Dermatologic 1 0.907 – 1.11 0.961 417 4368 exclusion phecode
696 Psoriasis and related disorders Dermatologic 1.04 0.994 – 1.09 0.0899 1999 21181 exclusion phecode
696.4 Psoriasis Dermatologic 1.04 0.997 – 1.09 0.0649 1949 20688 exclusion phecode
696.41 Psoriasis vulgaris Dermatologic 1.05 0.991 – 1.1 0.1 1482 15771 exclusion phecode
696.42 Psoriatic arthropathy Dermatologic 1.01 0.933 – 1.1 0.782 627 6658 exclusion phecode
697 Sarcoidosis Dermatologic 1.09 0.993 – 1.2 0.071 487 5093 exclusion phecode
698 Pruritus and related conditions Dermatologic 1.02 0.941 – 1.1 0.673 713 7402 exclusion phecode
700 Corns and callosities Dermatologic 0.989 0.874 – 1.12 0.865 268 2749 exclusion phecode
701
Other hypertrophic and atrophic conditions of
Other hypertrophic and atrophic conditions of skin
 Dermatologic 1 0.973 – 1.04 0.807 4339 44148 exclusion phecode
701.1 Keratoderma, acquired Dermatologic 1.11 0.885 – 1.4 0.361 81 797 exclusion phecode
701.2 Scar conditions and fibrosis of skin Dermatologic 0.998 0.956 – 1.04 0.942 2223 22237 exclusion phecode
701.3 Circumscribed scleroderma Dermatologic 1.1 0.831 – 1.45 0.515 54 587 exclusion phecode
701.4 Keloid scar Dermatologic 1.02 0.887 – 1.18 0.745 202 2074 exclusion phecode
701.5 Abnormal granulation tissue Dermatologic 0.962 0.872 – 1.06 0.441 422 4348 exclusion phecode
701.6 Acquired acanthosis nigricans Dermatologic 1.13 0.914 – 1.39 0.264 92 974 exclusion phecode
702
Degenerative skin conditions and other
Degenerative skin conditions and other dermatoses
 Dermatologic 1.01 0.984 – 1.04 0.376 5152 51237 exclusion phecode
702.1 Actinic keratosis Dermatologic 0.999 0.958 – 1.04 0.977 2428 24225 exclusion phecode
702.2 Seborrheic keratosis Dermatologic 1.03 0.989 – 1.07 0.17 2921 28890 exclusion phecode
703 Diseases of nail, NOS Dermatologic 1.01 0.895 – 1.13 0.929 320 3332 exclusion phecode
703.1 Ingrowing nail Dermatologic 1.02 0.95 – 1.09 0.606 838 9124 exclusion phecode
704 Diseases of hair and hair follicles Dermatologic 1.04 1.01 – 1.07 0.0135 4979 49801 exclusion phecode
704.1 Alopecia Dermatologic 1.15 0.947 – 1.39 0.161 117 1225 exclusion phecode
704.8
Other specified diseases of hair and hair
Other specified diseases of hair and hair follicles
 Dermatologic 1.06 0.843 – 1.34 0.607 74 717 exclusion phecode
705 Disorders of sweat glands Dermatologic 1.06 0.915 – 1.22 0.447 201 2187 exclusion phecode
705.3 Hidradenitis Dermatologic 1.03 0.878 – 1.21 0.707 164 1796 exclusion phecode
705.8 Hyperhidrosis Dermatologic 1.07 0.975 – 1.17 0.16 540 5540 exclusion phecode
706 Diseases of sebaceous glands Dermatologic 1.03 1.01 – 1.06 0.00442 7841 78625 exclusion phecode
706.1 Acne Dermatologic 1.18 0.924 – 1.5 0.188 73 733 exclusion phecode
706.2 Sebaceous cyst Dermatologic 1.03 1.01 – 1.06 0.00397 8282 83006 exclusion phecode
707 Chronic ulcer of skin Dermatologic 1 0.946 – 1.06 0.992 1374 18299 exclusion phecode
707.1 Decubitus ulcer Dermatologic 0.96 0.889 – 1.04 0.291 727 8446 exclusion phecode
709 Diffuse diseases of connective tissue Dermatologic 1.02 0.978 – 1.05 0.415 3018 32437 exclusion phecode
709.2 Sicca syndrome Dermatologic 1.01 0.921 – 1.11 0.807 479 4856 exclusion phecode
709.3 Systemic sclerosis Dermatologic 0.985 0.839 – 1.16 0.857 163 1671 exclusion phecode
709.6
Other specified diffuse diseases of connective
Other specified diffuse diseases of connective tissue
 Dermatologic 0.978 0.749 – 1.28 0.868 61 614 exclusion phecode
709.7 Unspecified diffuse connective tissue disease Dermatologic 1.02 0.973 – 1.06 0.473 2346 25597 exclusion phecode
710
Osteomyelitis, periostitis, and other
Osteomyelitis, periostitis, and other infections involving bone
 Musculoskeletal 1.01 0.917 – 1.12 0.803 427 5631 exclusion phecode
710.1 Osteomyelitis Musculoskeletal 1.03 0.93 – 1.15 0.552 387 5206 exclusion phecode
710.12 Chronic osteomyelitis Musculoskeletal 1.07 0.904 – 1.26 0.447 154 1841 exclusion phecode
710.19 Unspecified osteomyelitis Musculoskeletal 1 0.881 – 1.14 0.982 253 3710 exclusion phecode
711 Arthropathy associated with infections Musculoskeletal 1.01 0.91 – 1.13 0.811 368 3990 exclusion phecode
711.1 Pyogenic arthritis Musculoskeletal 1.06 0.934 – 1.2 0.375 282 3105 exclusion phecode
712 Infective connective tissue disorders Musculoskeletal 1.13 0.896 – 1.43 0.3 73 758 exclusion phecode
713
Arthropathy associated with other disorders
Arthropathy associated with other disorders classified elsewhere
 Musculoskeletal 0.768 0.613 – 0.963 0.0219 81 1415 exclusion phecode
713.5
Arthropathy associated with neurological
Arthropathy associated with neurological disorders
 Musculoskeletal 1.22 0.639 – 2.32 0.55 6 620 exclusion phecode
714
Rheumatoid arthritis and other inflammatory
Rheumatoid arthritis and other inflammatory polyarthropathies
 Musculoskeletal 1.08 1.04 – 1.11 4.14e-06 4357 45792 exclusion phecode
714.1 Rheumatoid arthritis Musculoskeletal 1.09 1.06 – 1.13 1.59e-07 3953 41437 exclusion phecode
715 Other inflammatory spondylopathies Musculoskeletal 1.01 0.959 – 1.06 0.702 1511 15657 exclusion phecode
715.1 Sacroiliitis NEC Musculoskeletal 1 0.822 – 1.22 0.973 106 1087 exclusion phecode
715.2 Ankylosing spondylitis Musculoskeletal 1.01 0.923 – 1.1 0.883 567 5804 exclusion phecode
716 Other arthropathies Musculoskeletal 1.02 1.01 – 1.03 0.00113 34189 251534 exclusion phecode
716.1 Unspecified polyarthropathy or polyarthritis Musculoskeletal 1.04 0.999 – 1.07 0.0594 3136 33100 exclusion phecode
716.2 Unspecified monoarthritis Musculoskeletal 1.02 1 – 1.04 0.0143 14255 146413 exclusion phecode
716.9 Arthropathy NOS Musculoskeletal 1.02 1.01 – 1.03 0.00134 32782 248570 exclusion phecode
717 Polymyalgia Rheumatica Musculoskeletal 1.07 1.01 – 1.14 0.0255 1056 10755 exclusion phecode
720 Spinal stenosis Musculoskeletal 1.03 0.993 – 1.07 0.115 3327 34811 exclusion phecode
721 Spondylosis and allied disorders Musculoskeletal 1.02 0.996 – 1.05 0.108 7082 73821 exclusion phecode
721.1 Spondylosis without myelopathy Musculoskeletal 1.03 0.997 – 1.06 0.0805 4568 47580 exclusion phecode
721.2 Spondylosis with myelopathy Musculoskeletal 1.14 0.97 – 1.35 0.11 162 1779 exclusion phecode
721.8 Other allied disorders of spine Musculoskeletal 1.03 0.917 – 1.15 0.634 322 3334 exclusion phecode
722 Intervertebral disc disorders Musculoskeletal 1.03 1.01 – 1.06 0.00569 8258 85149 exclusion phecode
722.1 Displacement of intervertebral disc Musculoskeletal 1.03 0.939 – 1.13 0.521 469 4833 exclusion phecode
722.6 Degeneration of intervertebral disc Musculoskeletal 1.03 0.994 – 1.08 0.0983 2598 26876 exclusion phecode
722.8 Postlaminectomy syndrome Musculoskeletal 1.07 0.836 – 1.37 0.596 65 636 exclusion phecode
722.9 Other and unspecified disc disorder Musculoskeletal 1.03 0.993 – 1.06 0.129 4073 41781 exclusion phecode
723 Other disorders of cervical region Musculoskeletal 1.16 1.06 – 1.28 0.00157 475 4864 exclusion phecode
723.1 Torticollis Musculoskeletal 1.35 1.1 – 1.66 0.00403 100 1017 exclusion phecode
724 Other and unspecified disorders of back Musculoskeletal 1 0.959 – 1.05 0.841 1902 19394 exclusion phecode
724.1 Disorders of sacrum Musculoskeletal 1.05 0.946 – 1.17 0.353 383 3847 exclusion phecode
724.2 Disorders of coccyx Musculoskeletal 1.06 0.95 – 1.17 0.314 386 3872 exclusion phecode
724.8 Other symptoms referable to back Musculoskeletal 1.35 1.02 – 1.79 0.0335 57 606 exclusion phecode
724.9 Other unspecified back disorders Musculoskeletal 0.983 0.932 – 1.04 0.522 1490 15196 exclusion phecode
726 Peripheral enthesopathies and allied syndromes Musculoskeletal 1.03 1.01 – 1.05 0.00161 13398 138816 exclusion phecode
726.1 Enthesopathy Musculoskeletal 1.03 1.01 – 1.05 0.0109 8757 90645 exclusion phecode
726.2 Synoviopathy Musculoskeletal 1.09 0.97 – 1.22 0.149 308 3177 exclusion phecode
726.3 Bursitis Musculoskeletal 1.09 1.01 – 1.17 0.0245 765 8075 exclusion phecode
727 Other disorders of synovium, tendon, and bursa Musculoskeletal 1.03 1.01 – 1.06 0.00836 6854 69603 exclusion phecode
727.1 Synovitis and tenosynovitis Musculoskeletal 1.05 1.01 – 1.09 0.0238 2522 26036 exclusion phecode
727.2 Bursitis disorders Musculoskeletal 0.989 0.803 – 1.22 0.918 92 978 exclusion phecode
727.4 Ganglion and cyst of synovium, tendon, and bursa Musculoskeletal 1.03 0.993 – 1.07 0.11 2939 29661 exclusion phecode
727.5 Rupture of synovium Musculoskeletal 0.972 0.89 – 1.06 0.534 542 5507 exclusion phecode
727.6 Rupture of tendon, nontraumatic Musculoskeletal 1.02 0.91 – 1.14 0.757 330 3313 exclusion phecode
727.7 Contracture of tendon (sheath) Musculoskeletal 1.02 0.856 – 1.21 0.833 136 1360 exclusion phecode
728 Disorders of muscle, ligament, and fascia Musculoskeletal 1.07 1.03 – 1.1 0.000458 3324 34058 exclusion phecode
728.2 Laxity of ligament or hypermobility syndrome Musculoskeletal 0.985 0.889 – 1.09 0.778 395 3962 exclusion phecode
728.7 Fasciitis Musculoskeletal 1.08 1.04 – 1.11 4.71e-05 3444 35266 exclusion phecode
728.71
Contracture of palmar fascia [Dupuytren's
Contracture of palmar fascia [Dupuytren's disease]
 Musculoskeletal 1.07 1.03 – 1.11 0.000237 3141 32186 exclusion phecode
729 Other disorders of soft tissues Musculoskeletal 1.03 0.997 – 1.05 0.0785 5430 57052 exclusion phecode
729.1 Rheumatism, unspecified and fibrositis Musculoskeletal 1.02 0.957 – 1.1 0.497 906 9645 exclusion phecode
729.3 Panniculitis Musculoskeletal 0.976 0.787 – 1.21 0.823 93 966 exclusion phecode
731
Osteitis deformans and osteopathies associated
Osteitis deformans and osteopathies associated with other disorders classified elsewhere
 Musculoskeletal 1.09 0.959 – 1.24 0.186 257 2633 exclusion phecode
731.1 Osteitis deformans [Paget's disease of bone] Musculoskeletal 1.09 0.954 – 1.24 0.212 243 2487 exclusion phecode
732 Osteochondropathies Musculoskeletal 1.03 0.935 – 1.14 0.545 447 4441 exclusion phecode
732.1 Juvenile osteochondrosis Musculoskeletal 1.1 0.955 – 1.28 0.18 195 1952 exclusion phecode
732.7 Osteochondritis dissecans Musculoskeletal 0.848 0.645 – 1.12 0.239 57 541 exclusion phecode
733 Other disorders of bone and cartilage Musculoskeletal 1.01 0.962 – 1.06 0.639 1668 16864 exclusion phecode
733.2 Cyst of bone Musculoskeletal 0.947 0.841 – 1.07 0.366 299 2943 exclusion phecode
733.4 Aseptic necrosis of bone Musculoskeletal 0.991 0.904 – 1.09 0.842 499 5091 exclusion phecode
733.6 Costochondritis Musculoskeletal 1.09 0.903 – 1.31 0.373 122 1218 exclusion phecode
733.8 Malunion and nonunion of fracture Musculoskeletal 1.03 0.97 – 1.09 0.335 1154 11673 exclusion phecode
733.9 Chondromalacia Musculoskeletal 1.14 0.934 – 1.38 0.2 114 1150 exclusion phecode
735 Acquired foot deformities Musculoskeletal 1.01 0.99 – 1.03 0.295 9254 91386 exclusion phecode
735.1 Flat foot Musculoskeletal 1.11 0.955 – 1.3 0.173 185 1810 exclusion phecode
735.2 Acquired toe deformities Musculoskeletal 0.992 0.963 – 1.02 0.573 4866 48115 exclusion phecode
735.21 Hammer toe (acquired) Musculoskeletal 0.979 0.933 – 1.03 0.381 1850 18337 exclusion phecode
735.23 Hallux rigidus Musculoskeletal 1.01 0.958 – 1.07 0.704 1498 14710 exclusion phecode
735.3 Hallux valgus (Bunion) Musculoskeletal 1.01 0.984 – 1.04 0.467 6437 63406 exclusion phecode
736 Other acquired deformities of limbs Musculoskeletal 1.05 1 – 1.11 0.0484 1512 15264 exclusion phecode
736.2 Acquired deformities of finger Musculoskeletal 0.983 0.86 – 1.12 0.803 239 2337 exclusion phecode
737 Curvature of spine Musculoskeletal 0.953 0.894 – 1.02 0.139 1067 10715 exclusion phecode
737.3 Kyphoscoliosis and scoliosis Musculoskeletal 0.94 0.88 – 1 0.0626 1008 10064 exclusion phecode
738 Other acquired musculoskeletal deformity Musculoskeletal 0.982 0.935 – 1.03 0.475 1753 18065 exclusion phecode
738.4 Acquired spondylolisthesis Musculoskeletal 0.981 0.929 – 1.04 0.5 1392 14362 exclusion phecode
739 Contracture of joint Musculoskeletal 1.13 1.02 – 1.24 0.0161 454 4621 exclusion phecode
740 Osteoarthrosis Musculoskeletal 1 0.989 – 1.02 0.765 25395 218276 exclusion phecode
740.1 Osteoarthritis; localized Musculoskeletal 1 0.986 – 1.02 0.762 16122 159216 exclusion phecode
740.11 Osteoarthrosis, localized, primary Musculoskeletal 1 0.982 – 1.03 0.671 8251 84140 exclusion phecode
740.12 Osteoarthrosis, localized, secondary Musculoskeletal 1.01 0.902 – 1.13 0.878 327 3292 exclusion phecode
740.2 Osteoarthrosis, generalized Musculoskeletal 0.991 0.908 – 1.08 0.845 551 5605 exclusion phecode
740.9 Osteoarthrosis NOS Musculoskeletal 1 0.985 – 1.02 0.674 11062 115758 exclusion phecode
741 Symptoms and disorders of the joints Musculoskeletal 1.05 1.02 – 1.09 0.00547 3265 33551 exclusion phecode
741.1 Ankylosis of joint Musculoskeletal 1.13 0.923 – 1.39 0.234 96 953 exclusion phecode
741.2 Stiffness of joint Musculoskeletal 1.13 1.04 – 1.23 0.00507 569 5806 exclusion phecode
741.3 Difficulty in walking Musculoskeletal 0.962 0.805 – 1.15 0.668 126 1431 exclusion phecode
741.4 Joint effusions Musculoskeletal 1.05 0.993 – 1.11 0.0831 1283 13289 exclusion phecode
741.5 Hemarthrosis Musculoskeletal 1.12 0.92 – 1.37 0.254 101 1036 exclusion phecode
741.6 Villonodular synovitis Musculoskeletal 1.21 0.913 – 1.6 0.187 51 514 exclusion phecode
742 Derangement of joint, non-traumatic Musculoskeletal 1.03 0.986 – 1.07 0.216 2680 27102 exclusion phecode
742.1 Loose body in joint Musculoskeletal 0.957 0.853 – 1.07 0.456 315 3159 exclusion phecode
742.2
Pathological, developmental or recurrent
Pathological, developmental or recurrent dislocation
 Musculoskeletal 1.17 0.942 – 1.45 0.157 87 934 exclusion phecode
742.8 Articular cartilage disorder Musculoskeletal 1.05 0.95 – 1.15 0.361 459 4762 exclusion phecode
742.9 Other derangement of joint Musculoskeletal 1.02 0.976 – 1.07 0.335 1898 19016 exclusion phecode
743
Osteoporosis, osteopenia and pathological
Osteoporosis, osteopenia and pathological fracture
 Musculoskeletal 0.988 0.964 – 1.01 0.334 7063 71598 exclusion phecode
743.1 Osteoporosis Musculoskeletal 0.982 0.957 – 1.01 0.19 5975 60607 exclusion phecode
743.11 Osteoporosis NOS Musculoskeletal 0.983 0.956 – 1.01 0.253 5187 52642 exclusion phecode
743.13 Other specified osteoporosis Musculoskeletal 0.999 0.911 – 1.1 0.987 487 4960 exclusion phecode
743.2 Pathologic fracture Musculoskeletal 0.967 0.88 – 1.06 0.491 470 4849 exclusion phecode
743.9
Osteopenia or other disorder of bone and
Osteopenia or other disorder of bone and cartilage
 Musculoskeletal 1.02 0.942 – 1.09 0.689 771 7736 exclusion phecode
745 Pain in joint Musculoskeletal 1.02 1 – 1.05 0.0541 7314 75549 exclusion phecode
747 Cardiac and circulatory congenital anomalies Congenital Anomalies 1.01 0.973 – 1.06 0.49 2444 26246 exclusion phecode
747.1 Cardiac congenital anomalies Congenital Anomalies 1.02 0.977 – 1.06 0.362 2282 24611 exclusion phecode
747.11 Cardiac shunt/ heart septal defect Congenital Anomalies 0.957 0.877 – 1.04 0.327 552 5570 exclusion phecode
747.12 Valvular heart disease/ heart chambers Congenital Anomalies 0.928 0.811 – 1.06 0.278 222 2232 exclusion phecode
747.13 Congenital anomalies of great vessels Congenital Anomalies 1.07 1.01 – 1.12 0.0174 1517 16840 exclusion phecode
747.2
Congenital anomalies of peripheral vascular
Congenital anomalies of peripheral vascular system
 Congenital Anomalies 0.908 0.768 – 1.07 0.258 154 1589 exclusion phecode
748 Anomalies of respiratory system, congenital Congenital Anomalies 0.97 0.741 – 1.27 0.823 49 479 exclusion phecode
749 Congenital anomalies of face and neck Congenital Anomalies 0.892 0.79 – 1.01 0.067 282 2892 exclusion phecode
750 Digestive congenital anomalies Congenital Anomalies 0.92 0.848 – 0.999 0.0461 646 6422 exclusion phecode
750.1 Upper gastrointestinal congenital anomalies Congenital Anomalies 0.947 0.84 – 1.07 0.375 304 3046 exclusion phecode
750.13 Congenital anomalies of mouth/tongue Congenital Anomalies 1.02 0.873 – 1.19 0.801 182 1772 exclusion phecode
750.2 Lower gastrointestinal congenital anomalies Congenital Anomalies 0.892 0.797 – 0.999 0.0485 338 3363 exclusion phecode
750.21 Congenital anomalies of intestine Congenital Anomalies 0.89 0.774 – 1.02 0.1 217 2115 exclusion phecode
750.22
Congenital anomaly of gallbladder, bile ducts
Congenital anomaly of gallbladder, bile ducts, liver, pancreas
 Congenital Anomalies 0.918 0.752 – 1.12 0.398 110 1119 exclusion phecode
751 Genitourinary congenital anomalies Congenital Anomalies 0.961 0.91 – 1.01 0.153 1418 14452 exclusion phecode
751.1 Congenital anomalies of genital organs Congenital Anomalies 1.01 0.929 – 1.09 0.872 661 6602 exclusion phecode
751.11 Congenital anomalies of female genital organs Congenital Anomalies 1 0.908 – 1.1 0.977 442 4394 exclusion phecode
751.12 Congenital anomalies of male genital organs Congenital Anomalies 1 0.862 – 1.16 0.989 202 2042 exclusion phecode
751.2 Congenital anomalies of urinary system Congenital Anomalies 0.931 0.863 – 1 0.0598 759 7863 exclusion phecode
751.21 Cystic kidney disease Congenital Anomalies 0.964 0.866 – 1.07 0.494 380 3981 exclusion phecode
751.22 Other specified congenital anomalies of kidney Congenital Anomalies 0.937 0.833 – 1.05 0.275 301 3141 exclusion phecode
752 Nervous system congenital anomalies Congenital Anomalies 0.997 0.886 – 1.12 0.961 310 3151 exclusion phecode
752.1 Neural tube defects Congenital Anomalies 0.991 0.868 – 1.13 0.899 242 2440 exclusion phecode
752.11 Spina bifida Congenital Anomalies 0.97 0.84 – 1.12 0.675 201 2013 exclusion phecode
752.2
Other specified congenital anomalies of nervous
Other specified congenital anomalies of nervous system
 Congenital Anomalies 0.88 0.689 – 1.12 0.306 71 739 exclusion phecode
753 Congenital anomalies of the eye Congenital Anomalies 1.21 0.999 – 1.46 0.0518 120 1197 exclusion phecode
753.1 Congenital cataract and lens anomalies Congenital Anomalies 1.24 0.974 – 1.58 0.0813 72 716 exclusion phecode
754 Congenital musculoskeletal deformities of spine Congenital Anomalies 1.08 0.89 – 1.32 0.427 103 1041 exclusion phecode
755 Congenital anomalies of limbs Congenital Anomalies 1.02 0.922 – 1.13 0.698 408 4087 exclusion phecode
755.1 Congenital deformities of feet Congenital Anomalies 1.03 0.896 – 1.19 0.656 193 1984 exclusion phecode
755.6
Other congenital anomalies of lower limb
Other congenital anomalies of lower limb, including pelvic girdle
 Congenital Anomalies 0.942 0.798 – 1.11 0.482 159 1556 exclusion phecode
755.61 Congenital hip dysplasia and deformity Congenital Anomalies 0.962 0.782 – 1.18 0.718 106 1033 exclusion phecode
756 Other congenital musculoskeletal anomalies Congenital Anomalies 1.03 0.948 – 1.13 0.457 553 5548 exclusion phecode
756.3
Congenital anomalies of muscle, tendon, fascia
Congenital anomalies of muscle, tendon, fascia, and connective tissue
 Congenital Anomalies 1.01 0.806 – 1.28 0.905 78 768 exclusion phecode
756.5 Congenital osteodystrophies Congenital Anomalies 1.07 0.965 – 1.18 0.204 408 4121 exclusion phecode
758 Chromosomal anomalies and genetic disorders Congenital Anomalies 0.998 0.845 – 1.18 0.985 142 1619 exclusion phecode
758.1 Chromosomal anomalies Congenital Anomalies 0.924 0.711 – 1.2 0.556 57 793 exclusion phecode
759 Other and unspecified congenital anomalies Congenital Anomalies 0.993 0.862 – 1.14 0.923 204 2055 exclusion phecode
759.1 Anomalies of endocrine glands, congenital Congenital Anomalies 0.901 0.729 – 1.11 0.331 91 912 exclusion phecode
760 Back pain Symptoms 1.03 1.01 – 1.05 0.0112 10118 105492 exclusion phecode
761 Cervicalgia Symptoms 1.03 0.982 – 1.09 0.202 1629 16951 exclusion phecode
764 Sciatica Symptoms 1.03 0.981 – 1.07 0.265 2185 22486 exclusion phecode
766 Neuralgia, neuritis, and radiculitis NOS Symptoms 1.02 0.96 – 1.09 0.483 1070 11115 exclusion phecode
770 Myalgia and myositis unspecified Symptoms 1.01 0.929 – 1.1 0.786 569 5994 exclusion phecode
771 Musculoskeletal symptoms referable to limbs Symptoms 1.06 0.988 – 1.14 0.101 778 8187 exclusion phecode
771.1 Swelling of limb Symptoms 1.02 0.988 – 1.05 0.222 4161 43631 exclusion phecode
772 Symptoms of the muscles Symptoms 0.992 0.911 – 1.08 0.861 584 6195 exclusion phecode
773 Pain in limb Symptoms 1.01 0.986 – 1.04 0.344 5628 58848 exclusion phecode
780 Hypothermia/Chills Symptoms 0.924 0.778 – 1.1 0.368 140 1635 exclusion phecode
781
Symptoms involving nervous and musculoskeletal
Symptoms involving nervous and musculoskeletal systems
 Symptoms 0.997 0.949 – 1.05 0.919 1659 17686 exclusion phecode
782.3 Edema Symptoms 1.01 0.96 – 1.07 0.603 1365 15365 exclusion phecode
782.6 Pallor and flushing Symptoms 1.1 0.934 – 1.29 0.254 153 1650 exclusion phecode
783 Fever of unknown origin Symptoms 1.02 0.987 – 1.06 0.229 3539 36765 exclusion phecode
785 Abdominal pain Symptoms 1.02 1.01 – 1.04 9.3e-06 37406 286103 exclusion phecode
788 Syncope and collapse Symptoms 1.02 0.996 – 1.04 0.113 8117 85154 exclusion phecode
789 Nausea and vomiting Symptoms 1.03 1.01 – 1.05 0.00403 10410 109905 exclusion phecode
790 Nonspecific findings on examination of blood Symptoms 0.962 0.805 – 1.15 0.668 141 1405 exclusion phecode
790.1 Elevated sedimentation rate Symptoms 0.957 0.761 – 1.2 0.71 76 782 exclusion phecode
790.6 Other abnormal blood chemistry Symptoms 0.997 0.971 – 1.02 0.855 5705 58767 exclusion phecode
791 Gangrene Symptoms 1.04 0.939 – 1.15 0.447 382 5152 exclusion phecode
792
Abnormal Papanicolaou smear of cervix and
Abnormal Papanicolaou smear of cervix and cervical HPV
 Symptoms 0.889 0.715 – 1.1 0.289 95 925 exclusion phecode
793
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of musculoskeletal system
 Symptoms 1.02 0.846 – 1.23 0.843 116 1249 exclusion phecode
793.2
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of other intrathoracic organs (echocardiogram, etc)
 Symptoms 1.02 0.936 – 1.12 0.615 520 5317 exclusion phecode
794
Abnormal results of other function studies
Abnormal results of other function studies (bladder, pancreas, placenta, spleen, etc)
 Symptoms 0.955 0.785 – 1.16 0.645 113 1158 exclusion phecode
797 Shock Symptoms 0.902 0.753 – 1.08 0.266 126 1455 exclusion phecode
797.1 Cardiogenic shock Symptoms 0.827 0.651 – 1.05 0.121 75 944 exclusion phecode
798 Malaise and fatigue Symptoms 1.02 0.985 – 1.06 0.239 3074 32254 exclusion phecode
798.1 Chronic fatigue syndrome Symptoms 1 0.921 – 1.1 0.928 548 5681 exclusion phecode
800 Fracture of lower limb Injuries & Poisonings 1.01 0.986 – 1.04 0.389 6478 66496 exclusion phecode
800.1 Fracture of neck of femur Injuries & Poisonings 0.961 0.914 – 1.01 0.119 1668 17025 exclusion phecode
800.2 Fracture of unspecified part of femur Injuries & Poisonings 0.998 0.846 – 1.18 0.981 151 1587 exclusion phecode
800.3 Fracture of tibia and fibula Injuries & Poisonings 1.02 0.972 – 1.06 0.47 2001 20477 exclusion phecode
800.4 Fracture of patella Injuries & Poisonings 1.1 1.01 – 1.18 0.0196 709 7196 exclusion phecode
801 Fracture of ankle and foot Injuries & Poisonings 1.04 0.99 – 1.08 0.131 2048 20884 exclusion phecode
801.1 Fracture of foot Injuries & Poisonings 1.04 0.991 – 1.09 0.106 1708 17374 exclusion phecode
802 Fracture of pelvis Injuries & Poisonings 0.997 0.921 – 1.08 0.948 675 6757 exclusion phecode
803 Fracture of upper limb Injuries & Poisonings 0.977 0.955 – 1 0.0524 7835 78638 exclusion phecode
803.1 Fracture of humerus Injuries & Poisonings 0.99 0.939 – 1.04 0.691 1532 15970 exclusion phecode
803.2 Fracture of radius and ulna Injuries & Poisonings 0.965 0.938 – 0.994 0.0169 5004 49646 exclusion phecode
803.3 Fracture of clavicle or scapula Injuries & Poisonings 0.998 0.946 – 1.05 0.953 1422 14317 exclusion phecode
804 Fracture of hand or wrist Injuries & Poisonings 1.01 0.971 – 1.04 0.711 3172 31635 exclusion phecode
805
Fracture of vertebral column without mention of
Fracture of vertebral column without mention of spinal cord injury
 Injuries & Poisonings 0.966 0.912 – 1.02 0.236 1253 12743 exclusion phecode
807 Fracture of ribs Injuries & Poisonings 1.03 0.957 – 1.11 0.413 723 7285 exclusion phecode
809 Fracture of unspecified bones Injuries & Poisonings 0.932 0.879 – 0.989 0.02 1195 12215 exclusion phecode
817 Concussion Injuries & Poisonings 0.936 0.818 – 1.07 0.338 228 2295 exclusion phecode
818 Intracranial hemorrhage (injury) Injuries & Poisonings 1.09 0.994 – 1.2 0.067 469 4844 exclusion phecode
819
Skull and face fracture and other intercranial
Skull and face fracture and other intercranial injury
 Injuries & Poisonings 1.02 0.979 – 1.06 0.366 2780 27999 exclusion phecode
823 Torus fracture Injuries & Poisonings 0.999 0.948 – 1.05 0.959 1553 15891 exclusion phecode
830 Dislocation Injuries & Poisonings 1.03 0.98 – 1.07 0.264 1981 19750 exclusion phecode
835 Internal derangement of knee Injuries & Poisonings 1.03 1.01 – 1.04 0.00368 14368 143917 exclusion phecode
836 Traumatic arthropathy Injuries & Poisonings 1.03 0.941 – 1.13 0.504 489 4961 exclusion phecode
840 Sprains and strains Injuries & Poisonings 0.932 0.847 – 1.03 0.149 455 4463 exclusion phecode
850 Hemorrhage or hematoma complicating a procedure Injuries & Poisonings 1.04 1.01 – 1.07 0.0141 4831 49685 exclusion phecode
851
Complications of transplants and reattached
Complications of transplants and reattached limbs
 Injuries & Poisonings 1.21 1.02 – 1.43 0.0272 142 1484 exclusion phecode
853 Complication of colostomy or enterostomy Injuries & Poisonings 1.06 0.965 – 1.17 0.214 445 4715 exclusion phecode
854
Complications of cardiac/vascular device
Complications of cardiac/vascular device, implant, and graft
 Injuries & Poisonings 1.03 0.979 – 1.09 0.238 1490 16959 exclusion phecode
857
Mechanical complication of unspecified
Mechanical complication of unspecified genitourinary device, implant, and graft
 Injuries & Poisonings 1.01 0.951 – 1.07 0.733 1115 11686 exclusion phecode
858 Complication of internal orthopedic device Injuries & Poisonings 1.02 0.98 – 1.06 0.362 2928 29749 exclusion phecode
859
Complication due to other implant and internal
Complication due to other implant and internal device
 Injuries & Poisonings 1.01 0.97 – 1.05 0.712 2992 30725 exclusion phecode
860 Bone marrow or stem cell transplant Neoplasms 1.2 0.93 – 1.55 0.161 63 644 exclusion phecode
870 Open wounds of head; neck; and trunk Injuries & Poisonings 1.02 0.984 – 1.06 0.268 3232 32981 exclusion phecode
870.1 Open wound or laceration of eye or eyelid Injuries & Poisonings 1 0.88 – 1.14 0.974 253 2529 exclusion phecode
870.2 Open wound of ear Injuries & Poisonings 1.13 0.966 – 1.31 0.13 179 1833 exclusion phecode
870.3 Other open wound of head and face Injuries & Poisonings 1 0.966 – 1.05 0.808 2688 27359 exclusion phecode
870.4 Open wound of nose and sinus Injuries & Poisonings 0.98 0.846 – 1.13 0.782 205 2060 exclusion phecode
870.6 Open wound of neck Injuries & Poisonings 1.07 0.835 – 1.38 0.585 62 648 exclusion phecode
871 Open wounds of extremities Injuries & Poisonings 1.01 0.974 – 1.04 0.694 3818 38378 exclusion phecode
871.1 Open wound of hand except finger(s) Injuries & Poisonings 1.15 0.841 – 1.57 0.381 48 492 exclusion phecode
871.2 Open wound of finger(s) Injuries & Poisonings 0.988 0.79 – 1.24 0.916 85 831 exclusion phecode
871.3 Open wound of foot except toe(s) alone Injuries & Poisonings 0.94 0.799 – 1.11 0.453 152 1697 exclusion phecode
872 Traumatic amputation Injuries & Poisonings 0.925 0.839 – 1.02 0.119 445 4452 exclusion phecode
873 Broken tooth Injuries & Poisonings 0.91 0.791 – 1.05 0.185 206 2153 exclusion phecode
874 Complication of amputation stump Injuries & Poisonings 1.12 0.93 – 1.34 0.237 118 1601 exclusion phecode
905
Late effects of musculoskeletal and connective
Late effects of musculoskeletal and connective tissue injuries
 Injuries & Poisonings 0.889 0.75 – 1.05 0.172 147 1473 exclusion phecode
907 Injuries to the nervous system Injuries & Poisonings 1.02 0.964 – 1.08 0.473 1248 12415 exclusion phecode
915 Superficial injury without mention of infection Injuries & Poisonings 1.01 0.978 – 1.04 0.527 3823 40191 exclusion phecode
916 Contusion Injuries & Poisonings 1.02 0.965 – 1.08 0.483 1326 13662 exclusion phecode
930 Allergic reaction to food Injuries & Poisonings 0.945 0.807 – 1.11 0.483 166 1721 exclusion phecode
938 Dermatitis due to solar radiation Injuries & Poisonings 0.992 0.89 – 1.1 0.878 363 3639 exclusion phecode
938.2 Chronic dermatitis due to solar radiation Injuries & Poisonings 0.955 0.834 – 1.09 0.508 236 2354 exclusion phecode
939
Atopic/contact dermatitis due to other or
Atopic/contact dermatitis due to other or unspecified
 Dermatologic 0.97 0.926 – 1.02 0.208 1938 19711 exclusion phecode
941 Adverse reaction to serum or vaccine Injuries & Poisonings 0.885 0.767 – 1.02 0.0948 204 2116 exclusion phecode
942 Infusion and transfusion reaction Injuries & Poisonings 1.25 1.02 – 1.54 0.0298 98 986 exclusion phecode
946 Anaphylactic shock NOS Injuries & Poisonings 0.992 0.904 – 1.09 0.874 487 5239 exclusion phecode
947 Urticaria Injuries & Poisonings 1.01 0.903 – 1.12 0.917 348 3538 exclusion phecode
949 Allergies, other Injuries & Poisonings 1.13 1.02 – 1.26 0.0221 367 3816 exclusion phecode
952
Spinal cord injury without evidence of spinal
Spinal cord injury without evidence of spinal bone injury
 Injuries & Poisonings 0.922 0.831 – 1.02 0.129 386 3967 exclusion phecode
957 Injury to other and unspecified nerves Injuries & Poisonings 1.26 1.11 – 1.43 0.000405 248 2544 exclusion phecode
958
Certain early complications of trauma or
Certain early complications of trauma or procedure
 Injuries & Poisonings 0.977 0.887 – 1.08 0.63 447 4626 exclusion phecode
958.1 Postoperative shock Injuries & Poisonings 1.35 0.984 – 1.86 0.0628 43 509 exclusion phecode
958.2 Traumatic and surgical subcutaneous emphysema Injuries & Poisonings 0.894 0.704 – 1.13 0.356 70 685 exclusion phecode
960 Poisoning by antibiotics Injuries & Poisonings 1.03 1.01 – 1.05 0.000373 16634 172453 exclusion phecode
960.2 Allergy/adverse effect of penicillin Injuries & Poisonings 1.02 1 – 1.04 0.0118 14535 150937 exclusion phecode
961 Poisoning by other anti-infectives Injuries & Poisonings 1.1 0.994 – 1.23 0.064 380 3984 exclusion phecode
961.1 Poisoning/allergy of sulfonamides Injuries & Poisonings 0.99 0.921 – 1.06 0.778 806 8332 exclusion phecode
962 Poisoning by hormones and synthetic substitutes Injuries & Poisonings 1.01 0.897 – 1.13 0.923 315 3517 exclusion phecode
962.3
Hormones and synthetic substitutes causing
Hormones and synthetic substitutes causing adverse effects in therapeutic use
 Injuries & Poisonings 1.01 0.902 – 1.14 0.823 307 3449 exclusion phecode
963 Poisoning by primarily systemic agents Injuries & Poisonings 1.03 0.898 – 1.19 0.654 210 2118 exclusion phecode
964
Poisoning by agents primarily affecting blood
Poisoning by agents primarily affecting blood constituents
 Injuries & Poisonings 0.967 0.849 – 1.1 0.614 240 2617 exclusion phecode
964.1 Anticoagulants causing adverse effects Injuries & Poisonings 0.958 0.838 – 1.1 0.532 234 2561 exclusion phecode
965
Poisoning by analgesics, antipyretics, and
Poisoning by analgesics, antipyretics, and antirheumatics
 Injuries & Poisonings 1.05 1.02 – 1.08 0.000223 5530 57958 exclusion phecode
965.1
Opiates and related narcotics causing adverse
Opiates and related narcotics causing adverse effects in therapeutic use
 Injuries & Poisonings 1.05 0.985 – 1.12 0.131 1038 10963 exclusion phecode
965.2
Antirheumatics causing adverse effects in
Antirheumatics causing adverse effects in therapeutic use
 Injuries & Poisonings 1.09 0.992 – 1.2 0.0737 433 4576 exclusion phecode
965.3
Salicylates causing adverse effects in
Salicylates causing adverse effects in therapeutic use
 Injuries & Poisonings 1.07 0.96 – 1.19 0.223 357 3825 exclusion phecode
966
Poisoning by anticonvulsants and
Poisoning by anticonvulsants and anti-Parkinsonism drugs
 Injuries & Poisonings 1.02 0.929 – 1.12 0.667 467 4894 exclusion phecode
967
Adverse effects of sedatives or other central
Adverse effects of sedatives or other central nervous system depressants and anesthetics
 Injuries & Poisonings 1.05 0.96 – 1.14 0.291 542 5559 exclusion phecode
969 Poisoning by psychotropic agents Injuries & Poisonings 1.02 0.971 – 1.07 0.436 1767 18683 exclusion phecode
971
Poisoning by drugs primarily affecting the
Poisoning by drugs primarily affecting the autonomic nervous system
 Injuries & Poisonings 0.896 0.765 – 1.05 0.176 168 1828 exclusion phecode
972
Poisoning by agents primarily affecting the
Poisoning by agents primarily affecting the cardiovascular system
 Injuries & Poisonings 1 0.872 – 1.15 0.994 227 2590 exclusion phecode
972.6 Antihypertensive agents causing adverse effects Injuries & Poisonings 0.925 0.731 – 1.17 0.515 70 809 exclusion phecode
973
Poisoning by agents primarily affecting the
Poisoning by agents primarily affecting the gastrointestinal system
 Injuries & Poisonings 0.922 0.748 – 1.14 0.443 96 1021 exclusion phecode
974
Poisoning by water, mineral, and uric acid
Poisoning by water, mineral, and uric acid metabolism drugs
 Injuries & Poisonings 1 0.807 – 1.25 0.978 83 947 exclusion phecode
975
Poisoning by agents primarily acting on the
Poisoning by agents primarily acting on the smooth and skeletal muscles and respiratory system
 Injuries & Poisonings 1.02 0.781 – 1.33 0.896 58 611 exclusion phecode
976
Poisoning by agents primarily affecting skin &
Poisoning by agents primarily affecting skin & mucous membrane, ophthalmological, otorhinolaryngological, & dental drugs
 Injuries & Poisonings 0.856 0.649 – 1.13 0.271 52 555 exclusion phecode
977 Personal history of allergy to medicinal agents Injuries & Poisonings 1.04 0.903 – 1.2 0.586 215 2208 exclusion phecode
979 Adverse drug events and drug allergies Injuries & Poisonings 1.06 0.974 – 1.14 0.187 636 6637 exclusion phecode
981
Toxic effect of (non-ethyl) alcohol and
Toxic effect of (non-ethyl) alcohol and petroleum and other solvents
 Injuries & Poisonings 1.02 0.876 – 1.18 0.811 182 1903 exclusion phecode
986 Toxic effect of carbon monoxide Injuries & Poisonings 1.13 0.874 – 1.46 0.351 58 584 exclusion phecode
987 Toxic effect of other gases, fumes, or vapors Injuries & Poisonings 1.19 0.956 – 1.47 0.12 93 988 exclusion phecode
988 Toxic effect of noxious substances eaten as food Injuries & Poisonings 0.889 0.727 – 1.09 0.247 102 1060 exclusion phecode
989
Toxic effect of other substances, chiefly
Toxic effect of other substances, chiefly nonmedicinal as to source
 Injuries & Poisonings 0.994 0.8 – 1.23 0.955 86 840 exclusion phecode
990 Effects radiation NOS Injuries & Poisonings 1.04 1.01 – 1.09 0.0254 2856 29168 exclusion phecode
994 Sepsis and SIRS Injuries & Poisonings 1.03 0.986 – 1.07 0.208 2636 28313 exclusion phecode
994.2 Sepsis Injuries & Poisonings 1.03 0.986 – 1.07 0.208 2636 28313 exclusion phecode
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