Departments of Anesthesiology and Biostatistics | University of Michigan

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Scores Type 2 diabetes UK Biobank (UKB) PheWAS analysis

Type 2 diabetes — UK Biobank (UKB) PRS PheWAS

PRS model
PRS ID exprsweb-t2d-29358691-gcst005413-pt-ukb-20211120Legacy PTC+T (DS)Large GWAS

Evaluation cohort: UK Biobank (UKB).

This page pairs the PheWAS plot with the full sortable table for the all-subject and exclusion scans.

Read the all-subject and exclusion scans separately. The combined view is only a browsing aid, and the selected-phecode panel below is only meaningful when the same phecode exists in both scans.

ExPRS exclusion definition

Exclusion cohort: individuals without Type 2 diabetes.

For this ExPRS, the exclusion sensitivity scan removes individuals with the exposure itself before rerunning the PheWAS. This is an exposure-based sensitivity analysis rather than a diagnosis-based exclusion.

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Signal overview

The plot gives a quick view of the currently visible associations. Click a point to pin its details, inspect that phecode across scans when both rows exist, or open the matching phecode detail page.

176 rows visible 16 categories
Phecode Description Category OR 95% CI P value Cases Controls Analysis Link
008 Intestinal infection Infectious Diseases 1.02 1 – 1.05 0.0273 8842 88430 all phecode
008.5 Bacterial enteritis Infectious Diseases 1.05 1 – 1.09 0.0273 2718 27172 all phecode
008.52 Intestinal infection due to C. difficile Infectious Diseases 0.988 0.911 – 1.07 0.759 653 6533 all phecode
008.6 Viral Enteritis Infectious Diseases 1.07 0.995 – 1.15 0.0674 862 8622 all phecode
008.7 Intestinal infection due to protozoa Infectious Diseases 1.22 0.919 – 1.61 0.172 55 550 all phecode
010 Tuberculosis Infectious Diseases 1.1 0.938 – 1.29 0.239 166 1659 all phecode
038 Septicemia Infectious Diseases 0.987 0.955 – 1.02 0.41 4175 41776 all phecode
038.1 Gram negative septicemia Infectious Diseases 1.01 0.944 – 1.09 0.691 850 8501 all phecode
038.2 Gram positive septicemia Infectious Diseases 0.96 0.876 – 1.05 0.387 494 4978 all phecode
041 Bacterial infection NOS Infectious Diseases 0.998 0.98 – 1.02 0.846 12017 120377 all phecode
041.1 Staphylococcus infections Infectious Diseases 1.01 0.971 – 1.05 0.684 3128 31348 all phecode
041.2 Streptococcus infection Infectious Diseases 0.984 0.935 – 1.04 0.537 1641 16433 all phecode
041.4 E. coli Infectious Diseases 0.984 0.946 – 1.02 0.431 2730 27319 all phecode
053 Herpes zoster Infectious Diseases 1.06 0.955 – 1.17 0.285 411 4137 all phecode
053.1 Herpes zoster with nervous system complications Infectious Diseases 0.986 0.804 – 1.21 0.893 95 949 all phecode
054 Herpes simplex Infectious Diseases 0.89 0.77 – 1.03 0.117 211 2107 all phecode
070 Viral hepatitis Infectious Diseases 0.959 0.884 – 1.04 0.325 590 5916 all phecode
070.1 Viral hepatitis A Infectious Diseases 1.14 0.889 – 1.46 0.301 69 690 all phecode
070.2 Viral hepatitis B Infectious Diseases 1.02 0.86 – 1.21 0.808 132 1330 all phecode
070.3 Viral hepatitis C Infectious Diseases 0.874 0.77 – 0.992 0.0373 255 2568 all phecode
070.4 Chronic hepatitis Infectious Diseases 0.992 0.876 – 1.12 0.897 276 2767 all phecode
070.9 Hepatitis NOS Infectious Diseases 1.08 0.974 – 1.19 0.149 428 4287 all phecode
071 Human immunodeficiency virus [HIV] disease Infectious Diseases 1.03 0.874 – 1.21 0.729 147 1467 all phecode
071.1 HIV infection, symptomatic Infectious Diseases 1.08 0.897 – 1.3 0.417 117 1168 all phecode
078 Viral warts & HPV Infectious Diseases 1.06 0.994 – 1.13 0.0737 1004 10036 all phecode
079 Viral infection Infectious Diseases 0.986 0.948 – 1.03 0.475 2769 27694 all phecode
079.1 Varicella infection Infectious Diseases 1.11 0.869 – 1.42 0.402 64 640 all phecode
080 Postoperative infection Infectious Diseases 0.994 0.964 – 1.03 0.705 4473 44775 all phecode
081
Infection/inflammation of internal prosthetic
Infection/inflammation of internal prosthetic device; implant; and graft
 Infectious Diseases 0.992 0.952 – 1.03 0.699 2477 24765 all phecode
090
Sexually transmitted infections (not HIV or
Sexually transmitted infections (not HIV or hepatitis)
 Infectious Diseases 1.15 0.904 – 1.45 0.262 71 709 all phecode
1000 Burns Injuries & Poisonings 0.935 0.859 – 1.02 0.125 578 5796 all phecode
1001 Foreign body injury Injuries & Poisonings 1.01 0.948 – 1.07 0.84 1199 12007 all phecode
1002
Symptoms concerning nutrition, metabolism, and
Symptoms concerning nutrition, metabolism, and development
 Injuries & Poisonings 1.01 0.98 – 1.04 0.57 5480 54819 all phecode
1004
Other signs and symptoms involving emotional
Other signs and symptoms involving emotional state
 Injuries & Poisonings 0.93 0.826 – 1.05 0.234 300 2997 all phecode
1005 Other symptoms Injuries & Poisonings 1 0.949 – 1.06 0.955 1444 14422 all phecode
1006 Crushing injury Injuries & Poisonings 0.925 0.813 – 1.05 0.232 256 2558 all phecode
1007 Injury to blood vessels Injuries & Poisonings 1.12 0.987 – 1.27 0.0784 256 2559 all phecode
1008 Crushing or internal injury to organs Injuries & Poisonings 0.977 0.916 – 1.04 0.475 1013 10132 all phecode
1009 Injury, NOS Injuries & Poisonings 0.985 0.963 – 1.01 0.183 8482 84911 all phecode
1010 Other tests Injuries & Poisonings 1.01 0.981 – 1.03 0.573 5945 59512 all phecode
1011 Complications of surgical and medical procedures Injuries & Poisonings 1 0.981 – 1.02 0.814 9152 91588 all phecode
1012 Late effect Injuries & Poisonings 1.19 0.983 – 1.44 0.0747 105 1057 all phecode
1013 Asphyxia and hypoxemia Injuries & Poisonings 0.984 0.876 – 1.1 0.784 316 3168 all phecode
1014 Effects of heat, cold and air pressure Injuries & Poisonings 1.09 0.85 – 1.4 0.49 66 659 all phecode
1015 Effects of other external causes Injuries & Poisonings 1.02 0.986 – 1.05 0.291 4226 42294 all phecode
1019
Other ill-defined and unknown causes of
Other ill-defined and unknown causes of morbidity and mortality
 Injuries & Poisonings 1.01 0.995 – 1.03 0.19 15895 159019 all phecode
110 Dermatophytosis / Dermatomycosis Infectious Diseases 0.989 0.875 – 1.12 0.855 279 2810 all phecode
110.1 Dermatophytosis Infectious Diseases 0.99 0.873 – 1.12 0.869 273 2750 all phecode
110.11 Dermatophytosis of nail Infectious Diseases 0.904 0.71 – 1.15 0.416 74 756 all phecode
110.12 Althete's foot Infectious Diseases 1.03 0.864 – 1.22 0.77 141 1410 all phecode
112 Candidiasis Infectious Diseases 0.985 0.942 – 1.03 0.508 2126 21275 all phecode
117 Mycoses Infectious Diseases 0.969 0.857 – 1.09 0.612 272 2719 all phecode
117.4 Aspergillosis Infectious Diseases 0.97 0.828 – 1.14 0.704 165 1650 all phecode
130 Spirochetal infection Infectious Diseases 0.822 0.65 – 1.04 0.102 80 800 all phecode
133 Arthropod-borne diseases Infectious Diseases 1.04 0.809 – 1.33 0.767 69 689 all phecode
134 Helminthiases Infectious Diseases 1.1 0.923 – 1.31 0.285 127 1267 all phecode
134.1 Intestinal helminthiases Infectious Diseases 1.09 0.906 – 1.32 0.355 106 1058 all phecode
136 Other infectious and parasitic diseases Infectious Diseases 1.16 1.01 – 1.33 0.0402 205 2050 all phecode
145 Cancer of mouth Neoplasms 1.02 0.939 – 1.11 0.641 642 6415 all phecode
145.2 Cancer of tongue Neoplasms 1.04 0.922 – 1.16 0.553 310 3096 all phecode
145.3 Cancer of major salivary glands Neoplasms 1.04 0.855 – 1.27 0.681 105 1049 all phecode
145.5 Cancer of the mouth floor Neoplasms 0.981 0.749 – 1.29 0.891 54 539 all phecode
149 Cancer of larynx, pharynx, nasal cavities Neoplasms 1 0.925 – 1.09 0.931 635 6342 all phecode
149.1 Cancer of oropharynx Neoplasms 0.978 0.855 – 1.12 0.751 252 2517 all phecode
149.4 Cancer of larynx Neoplasms 1.06 0.937 – 1.2 0.35 265 2640 all phecode
149.9 Cancer of of nasal cavities Neoplasms 1.03 0.788 – 1.34 0.849 57 570 all phecode
150 Cancer of esophagus Neoplasms 0.907 0.841 – 0.977 0.0105 762 7630 all phecode
151 Cancer of stomach Neoplasms 0.979 0.898 – 1.07 0.632 569 5696 all phecode
153 Colorectal cancer Neoplasms 1.02 0.989 – 1.05 0.213 4580 45799 all phecode
153.2 Colon cancer Neoplasms 1.01 0.97 – 1.04 0.737 3105 31046 all phecode
153.3
Malignant neoplasm of rectum, rectosigmoid
Malignant neoplasm of rectum, rectosigmoid junction, and anus
 Neoplasms 1.03 0.981 – 1.07 0.262 2164 21640 all phecode
155 Cancer of liver and intrahepatic bile duct Neoplasms 0.908 0.819 – 1.01 0.0698 400 4008 all phecode
155.1 Malignant neoplasm of liver, primary Neoplasms 0.914 0.778 – 1.07 0.274 158 1580 all phecode
157 Pancreatic cancer Neoplasms 1.08 0.995 – 1.17 0.0667 659 6582 all phecode
158
Neoplasm of unspecified nature of digestive
Neoplasm of unspecified nature of digestive system
 Neoplasms 0.995 0.933 – 1.06 0.884 1063 10635 all phecode
159
Malignant neoplasm of other and ill-defined
Malignant neoplasm of other and ill-defined sites within the digestive organs and peritoneum
 Neoplasms 1.01 0.987 – 1.04 0.296 5567 55694 all phecode
159.2
Malignant neoplasm of small intestine
Malignant neoplasm of small intestine, including duodenum
 Neoplasms 0.969 0.835 – 1.12 0.674 190 1900 all phecode
159.3
Malignant neoplasm of gallbladder and
Malignant neoplasm of gallbladder and extrahepatic bile ducts
 Neoplasms 1.03 0.886 – 1.19 0.735 205 2048 all phecode
159.4
Malignant neoplasm of retroperitoneum and
Malignant neoplasm of retroperitoneum and peritoneum
 Neoplasms 0.839 0.723 – 0.974 0.0211 193 1925 all phecode
164 Cancer of intrathoracic organs Neoplasms 1.04 0.817 – 1.33 0.746 60 600 all phecode
165 Cancer within the respiratory system Neoplasms 0.994 0.957 – 1.03 0.775 2824 28235 all phecode
165.1 Cancer of bronchus; lung Neoplasms 0.984 0.942 – 1.03 0.457 2230 22307 all phecode
170 Cancer of bone and connective tissue Neoplasms 0.96 0.868 – 1.06 0.43 437 4364 all phecode
170.1 Bone cancer Neoplasms 0.998 0.833 – 1.2 0.983 131 1309 all phecode
170.2 Cancer of connective tissue Neoplasms 0.937 0.833 – 1.05 0.271 331 3303 all phecode
172 Skin cancer Neoplasms 0.988 0.971 – 1.01 0.184 13495 134987 all phecode
172.1 Melanomas of skin, dx or hx Neoplasms 0.964 0.926 – 1 0.0685 2681 26792 all phecode
172.11 Melanomas of skin Neoplasms 0.963 0.925 – 1 0.0592 2713 27112 all phecode
172.2 Other non-epithelial cancer of skin Neoplasms 0.99 0.971 – 1.01 0.318 11000 110056 all phecode
172.3 Carcinoma in situ of skin Neoplasms 0.941 0.867 – 1.02 0.14 666 6656 all phecode
173 Neoplasm of uncertain behavior of skin Neoplasms 0.99 0.851 – 1.15 0.893 181 1818 all phecode
174 Breast cancer Neoplasms 1.01 0.991 – 1.03 0.317 12686 126597 all phecode
174.1 Breast cancer [female] Neoplasms 1.01 0.991 – 1.03 0.323 12476 124506 all phecode
174.11 Malignant neoplasm of female breast Neoplasms 1.01 0.989 – 1.03 0.396 11757 117502 all phecode
174.3 Neoplasm of uncertain behavior of breast Neoplasms 1.09 0.888 – 1.33 0.413 115 1148 all phecode
175 Acquired absence of breast Neoplasms 1 0.964 – 1.05 0.82 2400 24010 all phecode
180 Cervical cancer and dysplasia Neoplasms 0.986 0.943 – 1.03 0.529 2174 21747 all phecode
180.1 Cervical cancer Neoplasms 0.98 0.864 – 1.11 0.75 272 2720 all phecode
180.3
Cervical intraepithelial neoplasia [CIN]
Cervical intraepithelial neoplasia [CIN] [Cervical dysplasia]
 Neoplasms 0.988 0.945 – 1.03 0.603 2078 20784 all phecode
182 Malignant neoplasm of uterus Neoplasms 0.953 0.9 – 1.01 0.106 1282 12836 all phecode
184 Cancer of other female genital organs Neoplasms 1.01 0.956 – 1.07 0.692 1378 13772 all phecode
184.1
Malignant neoplasm of ovary and other uterine
Malignant neoplasm of ovary and other uterine adnexa
 Neoplasms 0.991 0.927 – 1.06 0.78 967 9667 all phecode
184.11 Malignant neoplasm of ovary Neoplasms 1 0.935 – 1.07 0.994 939 9387 all phecode
184.2
Cancer of other female genital organs
Cancer of other female genital organs (excluding uterus and ovary)
 Neoplasms 0.978 0.868 – 1.1 0.709 305 3049 all phecode
185 Cancer of prostate Neoplasms 1.04 1.01 – 1.07 0.00516 5974 58812 all phecode
187 Cancer of other male genital organs Neoplasms 1.06 0.963 – 1.17 0.229 449 4485 all phecode
187.1
Malignant neoplasm of unspecified male genital
Malignant neoplasm of unspecified male genital organ
 Neoplasms 0.846 0.662 – 1.08 0.181 70 700 all phecode
187.2 Malignant neoplasm of testis Neoplasms 1.04 0.924 – 1.18 0.493 287 2868 all phecode
187.8
Neoplasm of uncertain behavior of male genital
Neoplasm of uncertain behavior of male genital organs
 Neoplasms 1.23 1.01 – 1.5 0.0365 110 1098 all phecode
189
Cancer of urinary organs (incl. kidney and
Cancer of urinary organs (incl. kidney and bladder)
 Neoplasms 1.04 1.01 – 1.07 0.0207 4160 41604 all phecode
189.1 Cancer of kidney and renal pelvis Neoplasms 1.02 0.956 – 1.08 0.6 1073 10723 all phecode
189.11 Malignant neoplasm of kidney, except pelvis Neoplasms 1.02 0.96 – 1.09 0.493 1033 10324 all phecode
189.12 Malignant neoplasm of renal pelvis Neoplasms 0.89 0.687 – 1.15 0.378 66 660 all phecode
189.2 Cancer of bladder Neoplasms 1.06 1.02 – 1.1 0.00707 2409 24113 all phecode
189.21 Malignant neoplasm of bladder Neoplasms 1.05 1 – 1.1 0.0316 2142 21447 all phecode
189.4 Malignant neoplasm of other urinary organs Neoplasms 1.02 0.864 – 1.22 0.781 144 1439 all phecode
190 Cancer of eye Neoplasms 1.07 0.922 – 1.25 0.369 176 1758 all phecode
191
Manlignant and unknown neoplasms of brain and
Manlignant and unknown neoplasms of brain and nervous system
 Neoplasms 1.04 0.957 – 1.12 0.386 689 6879 all phecode
191.1 Cancer of brain and nervous system Neoplasms 1.06 0.976 – 1.16 0.158 566 5650 all phecode
191.11 Cancer of brain Neoplasms 1.08 0.99 – 1.18 0.081 525 5240 all phecode
193 Thyroid cancer Neoplasms 0.978 0.876 – 1.09 0.69 346 3466 all phecode
194 Cancer of other endocrine glands Neoplasms 0.891 0.717 – 1.11 0.298 95 949 all phecode
195 Cancer, suspected or other Neoplasms 1.01 0.993 – 1.03 0.267 16967 165463 all phecode
195.1 Malignant neoplasm, other Neoplasms 1.01 0.992 – 1.02 0.344 16267 159497 all phecode
197 Chemotherapy Neoplasms 1.01 0.994 – 1.02 0.236 21433 213213 all phecode
198 Secondary malignant neoplasm Neoplasms 1 0.98 – 1.02 0.913 9552 95503 all phecode
198.1 Secondary malignancy of lymph nodes Neoplasms 0.988 0.961 – 1.02 0.402 5368 53670 all phecode
198.2 Secondary malignancy of respiratory organs Neoplasms 0.962 0.921 – 1 0.0773 2267 22670 all phecode
198.3
Secondary malignant neoplasm of digestive
Secondary malignant neoplasm of digestive systems
 Neoplasms 0.972 0.922 – 1.02 0.29 1549 15496 all phecode
198.4 Secondary malignant neoplasm of liver Neoplasms 0.987 0.948 – 1.03 0.518 2665 26648 all phecode
198.5 Secondary malignancy of brain/spine Neoplasms 1.03 0.963 – 1.11 0.355 848 8473 all phecode
198.6 Secondary malignancy of bone Neoplasms 1.02 0.979 – 1.07 0.312 2161 21600 all phecode
198.7 Secondary malignant neoplasm of skin Neoplasms 0.985 0.846 – 1.15 0.85 188 1890 all phecode
199 Neoplasm of uncertain behavior Neoplasms 1.01 0.958 – 1.07 0.674 1432 14313 all phecode
199.4 Neurofibromatosis Neoplasms 0.985 0.798 – 1.22 0.885 95 950 all phecode
200 Myeloproliferative disease Neoplasms 1.08 1.01 – 1.15 0.0233 991 9911 all phecode
200.1 Polycythemia vera Neoplasms 1.1 0.991 – 1.22 0.0726 387 3867 all phecode
201 Hodgkin's disease Neoplasms 0.825 0.724 – 0.941 0.00402 259 2598 all phecode
202 Cancer of other lymphoid, histiocytic tissue Neoplasms 0.999 0.957 – 1.04 0.98 2264 22709 all phecode
202.2 Non-Hodgkins lymphoma Neoplasms 0.993 0.947 – 1.04 0.778 1802 18073 all phecode
202.21 Nodular lymphoma Neoplasms 1.04 0.938 – 1.16 0.438 363 3647 all phecode
202.24 Large cell lymphoma Neoplasms 1.03 0.943 – 1.12 0.539 581 5824 all phecode
204 Leukemia Neoplasms 1.04 0.987 – 1.09 0.149 1660 16630 all phecode
204.1 Lymphoid leukemia Neoplasms 1.13 1.04 – 1.23 0.00503 577 5784 all phecode
204.11 Lymphoid leukemia, acute Neoplasms 1.07 0.822 – 1.39 0.616 56 560 all phecode
204.12 Lymphoid leukemia, chronic Neoplasms 1.11 1.02 – 1.22 0.0209 507 5084 all phecode
204.2 Myeloid leukemia Neoplasms 1.01 0.918 – 1.11 0.832 462 4617 all phecode
204.21 Myeloid leukemia, acute Neoplasms 1 0.897 – 1.12 0.947 329 3287 all phecode
204.22 Myeloid leukemia, chronic Neoplasms 1.06 0.888 – 1.25 0.54 144 1440 all phecode
204.4 Multiple myeloma Neoplasms 0.956 0.877 – 1.04 0.311 555 5560 all phecode
208 Benign neoplasm of colon Neoplasms 1 0.99 – 1.02 0.581 19856 191891 all phecode
210 Benign neoplasm of lip, oral cavity, and pharynx Neoplasms 1.05 0.98 – 1.12 0.174 978 9781 all phecode
211
Benign neoplasm of other parts of digestive
Benign neoplasm of other parts of digestive system
 Neoplasms 1.02 0.989 – 1.05 0.238 5243 52452 all phecode
212
Benign neoplasm of respiratory and
Benign neoplasm of respiratory and intrathoracic organs
 Neoplasms 0.905 0.811 – 1.01 0.0757 347 3466 all phecode
213 Benign neoplasm of bone and articular cartilage Neoplasms 1.01 0.904 – 1.14 0.823 318 3187 all phecode
214 Lipoma Neoplasms 1.02 0.991 – 1.04 0.189 6231 62346 all phecode
214.1 Lipoma of skin and subcutaneous tissue Neoplasms 1.01 0.982 – 1.04 0.42 4585 45872 all phecode
215
Other benign neoplasm of connective and other
Other benign neoplasm of connective and other soft tissue
 Neoplasms 0.988 0.929 – 1.05 0.71 1107 11061 all phecode
216 Benign neoplasm of skin Neoplasms 1.01 0.984 – 1.03 0.561 7664 76660 all phecode
217 Vascular hamartomas and non-neoplastic nevi Neoplasms 1 0.924 – 1.09 0.928 632 6313 all phecode
217.1 Nevus, non-neoplastic Neoplasms 1.03 0.945 – 1.12 0.516 595 5943 all phecode
218 Benign neoplasm of uterus Neoplasms 1.01 0.987 – 1.03 0.494 10023 100200 all phecode
218.1 Uterine leiomyoma Neoplasms 1.01 0.991 – 1.03 0.273 10241 102376 all phecode
218.2 Other benign neoplasm of uterus Neoplasms 0.964 0.864 – 1.08 0.515 355 3548 all phecode
220 Benign neoplasm of ovary Neoplasms 1 0.948 – 1.06 0.98 1445 14483 all phecode
221 Benign neoplasm of other female genital organs Neoplasms 1.04 0.908 – 1.2 0.551 220 2196 all phecode
222 Benign neoplasm of male genital organs Neoplasms 0.982 0.839 – 1.15 0.821 160 1600 all phecode
223
Benign neoplasm of kidney and other urinary
Benign neoplasm of kidney and other urinary organs
 Neoplasms 0.973 0.83 – 1.14 0.733 173 1729 all phecode
224 Benign neoplasm of eye Neoplasms 1 0.841 – 1.2 0.959 129 1299 all phecode
224.1 Benign neoplasm of eye, uveal Neoplasms 1.15 0.896 – 1.48 0.272 67 680 all phecode
225
Benign neoplasm of brain and other parts of
Benign neoplasm of brain and other parts of nervous system
 Neoplasms 0.966 0.898 – 1.04 0.355 816 8155 all phecode
225.1
Benign neoplasm of brain, cranial nerves
Benign neoplasm of brain, cranial nerves, meninges
 Neoplasms 0.956 0.887 – 1.03 0.242 775 7756 all phecode
225.2 Benign neoplasm of spinal cord, meninges Neoplasms 1.04 0.806 – 1.34 0.763 59 589 all phecode
226 Benign neoplasm of thyroid glands Neoplasms 0.967 0.852 – 1.1 0.602 266 2664 all phecode
227
Benign neoplasm of other endocrine glands and
Benign neoplasm of other endocrine glands and related structures
 Neoplasms 0.976 0.91 – 1.05 0.497 861 8635 all phecode
227.1 Benign neoplasm of adrenal gland Neoplasms 1.07 0.922 – 1.24 0.377 186 1857 all phecode
227.2 Benign neoplasm of parathyroid gland Neoplasms 1.01 0.911 – 1.12 0.824 371 3709 all phecode
227.3
Benign neoplasm of pituitary gland and
Benign neoplasm of pituitary gland and craniopharyngeal duct (pouch)
 Neoplasms 0.916 0.814 – 1.03 0.148 309 3114 all phecode
228 Hemangioma and lymphangioma, any site Neoplasms 0.988 0.939 – 1.04 0.649 1596 15966 all phecode
229 Benign neoplasm of unspecified sites Neoplasms 0.968 0.928 – 1.01 0.131 2397 23955 all phecode
240 Simple and unspecified goiter Endocrine/metabolic 0.988 0.909 – 1.07 0.78 600 6016 all phecode
241 Nontoxic nodular goiter Endocrine/metabolic 0.973 0.915 – 1.04 0.388 1107 11092 all phecode
241.1 Nontoxic uninodular goiter Endocrine/metabolic 1.01 0.919 – 1.11 0.831 471 4706 all phecode
241.2 Nontoxic multinodular goiter Endocrine/metabolic 0.953 0.881 – 1.03 0.233 676 6784 all phecode
242 Thyrotoxicosis with or without goiter Endocrine/metabolic 1.03 0.984 – 1.08 0.19 1854 18531 all phecode
242.1 Graves' disease Endocrine/metabolic 0.998 0.907 – 1.1 0.972 456 4553 all phecode
242.2 Toxic multinodular goiter Endocrine/metabolic 0.96 0.775 – 1.19 0.708 91 910 all phecode
242.3 Exophthalmos Endocrine/metabolic 0.969 0.811 – 1.16 0.73 138 1379 all phecode
244 Hypothyroidism Endocrine/metabolic 1.02 1 – 1.04 0.0319 14590 145053 all phecode
244.1 Secondary hypothyroidism Endocrine/metabolic 0.986 0.928 – 1.05 0.661 1108 11079 all phecode
244.2 Acquired hypothyroidism Endocrine/metabolic 0.923 0.752 – 1.13 0.446 101 1010 all phecode
244.4 Hypothyroidism NOS Endocrine/metabolic 1.02 1 – 1.04 0.0306 13918 138926 all phecode
245 Thyroiditis Endocrine/metabolic 0.998 0.883 – 1.13 0.97 288 2877 all phecode
245.2 Chronic thyroiditis Endocrine/metabolic 1.02 0.887 – 1.17 0.776 218 2177 all phecode
245.21 Chronic lymphocytic thyroiditis Endocrine/metabolic 0.998 0.865 – 1.15 0.974 210 2097 all phecode
246 Other disorders of thyroid Endocrine/metabolic 1.01 0.91 – 1.12 0.851 397 3975 all phecode
250 Diabetes mellitus Endocrine/metabolic 1.35 1.33 – 1.37 3.02e-355 19787 186006 all phecode
250.1 Type 1 diabetes Endocrine/metabolic 1.46 1.4 – 1.52 3.83e-82 2758 27621 all phecode
250.11 Type 1 diabetes with ketoacidosis Endocrine/metabolic 1.45 1.27 – 1.65 2.99e-08 239 2389 all phecode
250.12 Type 1 diabetes with renal manifestations Endocrine/metabolic 1.43 1.15 – 1.79 0.00163 76 770 all phecode
250.13 Type 1 diabetes with ophthalmic manifestations Endocrine/metabolic 1.66 1.51 – 1.83 6e-25 473 4744 all phecode
250.14 Type 1 diabetes with neurological manifestations Endocrine/metabolic 1.37 1.17 – 1.61 9.78e-05 160 1610 all phecode
250.2 Type 2 diabetes Endocrine/metabolic 1.36 1.34 – 1.38 2.51e-333 17831 170202 all phecode
250.21 Type 2 diabetes with ketoacidosis Endocrine/metabolic 1.33 1.1 – 1.62 0.00339 104 1050 all phecode
250.22 Type 2 diabetes with renal manifestations Endocrine/metabolic 1.36 1.18 – 1.56 1.75e-05 200 2018 all phecode
250.23 Type 2 diabetes with ophthalmic manifestations Endocrine/metabolic 1.52 1.42 – 1.62 1.64e-36 986 9907 all phecode
250.24 Type 2 diabetes with neurological manifestations Endocrine/metabolic 1.39 1.27 – 1.52 5.43e-13 503 5066 all phecode
250.4 Abnormal glucose Endocrine/metabolic 1.24 1.14 – 1.34 1.27e-07 680 6827 all phecode
250.41 Impaired fasting glucose Endocrine/metabolic 1.2 1.06 – 1.35 0.00425 265 2659 all phecode
250.42 Other abnormal glucose Endocrine/metabolic 1.26 1.14 – 1.39 8.11e-06 416 4178 all phecode
250.5 Glycosuria or Acetonuria Endocrine/metabolic 1.13 0.953 – 1.35 0.156 131 1308 all phecode
250.6 Polyneuropathy in diabetes Endocrine/metabolic 1.42 1.28 – 1.59 9.78e-11 349 3495 all phecode
250.7 Diabetic retinopathy Endocrine/metabolic 1.5 1.42 – 1.59 5.69e-46 1329 13335 all phecode
251.1 Hypoglycemia Endocrine/metabolic 1.34 1.26 – 1.44 3.09e-18 932 9370 all phecode
252 Disorders of parathyroid gland Endocrine/metabolic 0.973 0.908 – 1.04 0.43 873 8719 all phecode
252.1 Hyperparathyroidism Endocrine/metabolic 0.954 0.887 – 1.03 0.203 781 7802 all phecode
252.2 Hypoparathyroidism Endocrine/metabolic 1.12 0.942 – 1.32 0.203 142 1418 all phecode
253
Disorders of the pituitary gland and its
Disorders of the pituitary gland and its hypothalamic control
 Endocrine/metabolic 0.99 0.914 – 1.07 0.801 681 6821 all phecode
253.1 Pituitary hyperfunction Endocrine/metabolic 0.951 0.817 – 1.11 0.517 187 1867 all phecode
253.11 Acromegaly and gigantism Endocrine/metabolic 0.93 0.753 – 1.15 0.503 95 949 all phecode
253.2 Pituitary hypofunction Endocrine/metabolic 1.04 0.917 – 1.18 0.529 260 2618 all phecode
253.3 Diabetes insipidus Endocrine/metabolic 0.852 0.685 – 1.06 0.152 92 919 all phecode
253.7 Other disorders of neurohypophysis Endocrine/metabolic 1.01 0.852 – 1.19 0.941 158 1578 all phecode
255 Disorders of adrenal glands Endocrine/metabolic 1.04 0.956 – 1.13 0.372 638 6374 all phecode
255.1 Adrenal hyperfunction Endocrine/metabolic 1.12 0.964 – 1.3 0.138 180 1797 all phecode
255.11 Cushing's syndrome Endocrine/metabolic 1.03 0.843 – 1.26 0.777 103 1029 all phecode
255.12 Hyperaldosteronism Endocrine/metabolic 1.31 1.04 – 1.64 0.0217 76 759 all phecode
255.2 Adrenal hypofunction Endocrine/metabolic 0.95 0.851 – 1.06 0.359 362 3617 all phecode
255.21 Glucocorticoid deficiency Endocrine/metabolic 0.953 0.854 – 1.06 0.396 361 3607 all phecode
256 Ovarian dysfunction Endocrine/metabolic 0.897 0.788 – 1.02 0.101 240 2397 all phecode
256.4 Polycystic ovaries Endocrine/metabolic 0.924 0.804 – 1.06 0.266 209 2088 all phecode
257 Testicular dysfunction Endocrine/metabolic 1.01 0.861 – 1.19 0.881 160 1619 all phecode
257.1 Testicular hypofunction Endocrine/metabolic 1.05 0.887 – 1.23 0.599 152 1539 all phecode
258 Iatrogenic endocrine disorders Endocrine/metabolic 1.1 0.898 – 1.36 0.348 102 1020 all phecode
259 Other endocrine disorders Endocrine/metabolic 1.01 0.854 – 1.2 0.901 149 1498 all phecode
260 Protein-calorie malnutrition Endocrine/metabolic 1.04 0.902 – 1.2 0.602 202 2018 all phecode
260.1 Cachexia Endocrine/metabolic 1.14 0.852 – 1.51 0.385 51 510 all phecode
260.6 Anorexia Endocrine/metabolic 0.964 0.897 – 1.04 0.315 830 8317 all phecode
261 Vitamin deficiency Endocrine/metabolic 1.06 0.997 – 1.12 0.063 1199 11974 all phecode
261.2 Vitamin B-complex deficiencies Endocrine/metabolic 1.06 0.985 – 1.15 0.116 755 7541 all phecode
261.4 Vitamin D deficiency Endocrine/metabolic 0.997 0.905 – 1.1 0.95 447 4462 all phecode
261.41 Rickets or osteomalacia Endocrine/metabolic 1.11 0.88 – 1.39 0.383 77 769 all phecode
262 Mineral deficiency NEC Endocrine/metabolic 0.977 0.858 – 1.11 0.727 241 2407 all phecode
269 Proteinuria Endocrine/metabolic 1.07 0.957 – 1.2 0.231 338 3378 all phecode
270
Disorders of protein plasma/amino-acid
Disorders of protein plasma/amino-acid transport and metabolism
 Endocrine/metabolic 1.01 0.895 – 1.13 0.923 303 3028 all phecode
270.3 Disorders of plasma protein metabolism Endocrine/metabolic 0.968 0.855 – 1.1 0.615 261 2608 all phecode
270.32 Paraproteinemia Endocrine/metabolic 0.986 0.852 – 1.14 0.855 191 1910 all phecode
270.33 Amyloidosis Endocrine/metabolic 1.05 0.871 – 1.27 0.603 113 1129 all phecode
270.35 Macroglobulinemia Endocrine/metabolic 0.917 0.718 – 1.17 0.489 69 689 all phecode
271
Disorders of carbohydrate transport and
Disorders of carbohydrate transport and metabolism
 Endocrine/metabolic 1.11 0.947 – 1.31 0.193 160 1600 all phecode
271.3
Intestinal disaccharidase deficiencies and
Intestinal disaccharidase deficiencies and disaccharide malabsorption
 Endocrine/metabolic 1.1 0.922 – 1.3 0.295 139 1391 all phecode
272 Disorders of lipoid metabolism Endocrine/metabolic 1.06 1.05 – 1.07 2.07e-23 34835 235433 all phecode
272.1 Hyperlipidemia Endocrine/metabolic 1.06 1.05 – 1.07 1.43e-23 34764 235203 all phecode
272.11 Hypercholesterolemia Endocrine/metabolic 1.06 1.05 – 1.07 5.06e-21 32324 228083 all phecode
272.12 Hyperglyceridemia Endocrine/metabolic 1.02 0.781 – 1.34 0.86 58 580 all phecode
272.13 Mixed hyperlipidemia Endocrine/metabolic 1.05 0.899 – 1.23 0.53 164 1637 all phecode
272.9 Unspecified disorder of lipoid metabolism Endocrine/metabolic 1.08 0.934 – 1.24 0.315 211 2109 all phecode
274 Gout and other crystal arthropathies Endocrine/metabolic 1 0.971 – 1.04 0.809 3724 37231 all phecode
274.1 Gout Endocrine/metabolic 0.999 0.964 – 1.04 0.971 3171 31705 all phecode
274.11 Gouty arthropathy Endocrine/metabolic 0.948 0.777 – 1.16 0.598 112 1119 all phecode
274.2 Crystal arthropathies Endocrine/metabolic 1.03 0.954 – 1.12 0.411 613 6124 all phecode
274.21 Chondrocalcinosis Endocrine/metabolic 1.03 0.946 – 1.13 0.476 558 5576 all phecode
275 Disorders of mineral metabolism Endocrine/metabolic 0.987 0.944 – 1.03 0.556 2107 21070 all phecode
275.1 Disorders of iron metabolism Hematopoietic 0.957 0.884 – 1.04 0.282 653 6535 all phecode
275.3 Disorders of magnesium metabolism Endocrine/metabolic 1.03 0.93 – 1.15 0.539 375 3745 all phecode
275.5 Disorders of calcium/phosphorus metabolism Endocrine/metabolic 0.996 0.939 – 1.06 0.89 1202 12019 all phecode
275.53 Disorders of phosphorus metabolism Endocrine/metabolic 1.04 0.889 – 1.21 0.636 171 1717 all phecode
276
Disorders of fluid, electrolyte, and acid-base
Disorders of fluid, electrolyte, and acid-base balance
 Endocrine/metabolic 1.02 0.997 – 1.05 0.0892 7284 72932 all phecode
276.1 Electrolyte imbalance Endocrine/metabolic 1.03 0.996 – 1.06 0.0811 4086 40930 all phecode
276.11 Hyperosmolality and/or hypernatremia Endocrine/metabolic 0.99 0.867 – 1.13 0.878 239 2409 all phecode
276.12 Hyposmolality and/or hyponatremia Endocrine/metabolic 1.03 0.98 – 1.08 0.247 1818 18200 all phecode
276.13 Hyperpotassemia Endocrine/metabolic 1.06 0.995 – 1.14 0.0683 969 9728 all phecode
276.14 Hypopotassemia Endocrine/metabolic 1.03 0.974 – 1.09 0.312 1424 14235 all phecode
276.4 Acid-base balance disorder Endocrine/metabolic 1.1 1.03 – 1.16 0.00338 1161 11629 all phecode
276.41 Acidosis Endocrine/metabolic 1.07 1.01 – 1.14 0.0319 1056 10577 all phecode
276.42 Alkalosis Endocrine/metabolic 1.2 0.984 – 1.46 0.0716 113 1129 all phecode
276.5 Hypovolemia Endocrine/metabolic 0.99 0.952 – 1.03 0.595 2827 28265 all phecode
276.6 Fluid overload Endocrine/metabolic 1.04 0.949 – 1.15 0.371 451 4535 all phecode
276.8 Polydipsia Endocrine/metabolic 1.01 0.847 – 1.21 0.897 128 1278 all phecode
277 Other disorders of metabolism Endocrine/metabolic 0.964 0.9 – 1.03 0.292 899 8977 all phecode
277.4 Disorders of bilirubin excretion Endocrine/metabolic 1.04 0.932 – 1.16 0.493 362 3613 all phecode
277.5 Other disorders of lipoid metabolism Endocrine/metabolic 1.18 1.03 – 1.35 0.0183 230 2298 all phecode
277.51 Lipoprotein disorders Endocrine/metabolic 1.28 0.949 – 1.72 0.107 52 520 all phecode
278 Overweight, obesity and other hyperalimentation Endocrine/metabolic 0.987 0.968 – 1.01 0.2 10804 108289 all phecode
278.1 Obesity Endocrine/metabolic 0.986 0.967 – 1.01 0.175 10642 106670 all phecode
278.3 Localized adiposity Endocrine/metabolic 1.08 0.862 – 1.34 0.517 84 838 all phecode
278.4 Abnormal weight gain Endocrine/metabolic 1 0.782 – 1.29 0.976 66 660 all phecode
279 Disorders involving the immune mechanism Endocrine/metabolic 1.01 0.891 – 1.15 0.849 250 2510 all phecode
279.1 Immunity deficiency Endocrine/metabolic 1.03 0.9 – 1.19 0.632 209 2100 all phecode
279.11 Deficiency of humoral immunity Endocrine/metabolic 0.943 0.795 – 1.12 0.502 138 1390 all phecode
279.7 Other immunological findings Endocrine/metabolic 0.913 0.802 – 1.04 0.164 248 2478 all phecode
280 Iron deficiency anemias Hematopoietic 1.04 1.01 – 1.06 0.00161 7610 76168 all phecode
280.1
Iron deficiency anemias, unspecified or not due
Iron deficiency anemias, unspecified or not due to blood loss
 Hematopoietic 1.04 1.02 – 1.07 0.000827 7311 73153 all phecode
280.2
Iron deficiency anemia secondary to blood loss
Iron deficiency anemia secondary to blood loss (chronic)
 Hematopoietic 1.01 0.921 – 1.12 0.766 452 4541 all phecode
281 Other deficiency anemia Hematopoietic 1 0.94 – 1.06 0.996 1112 11126 all phecode
281.1 Megaloblastic anemia Hematopoietic 1.01 0.945 – 1.07 0.845 1066 10669 all phecode
281.11 Pernicious anemia Hematopoietic 1.01 0.941 – 1.09 0.7 750 7514 all phecode
281.12 Other vitamin B12 deficiency anemia Hematopoietic 1.22 1.05 – 1.42 0.00957 177 1769 all phecode
281.13 Folate-deficiency anemia Hematopoietic 0.758 0.648 – 0.887 0.000526 183 1836 all phecode
281.9 Deficiency anemias Hematopoietic 1.04 0.783 – 1.38 0.797 54 538 all phecode
282 Hereditary hemolytic anemias Hematopoietic 1.03 0.881 – 1.22 0.679 150 1499 all phecode
282.8 Other hemoglobinopathies Hematopoietic 1.16 0.899 – 1.5 0.252 56 560 all phecode
282.9 Other hereditary hemolytic anemias Hematopoietic 1.01 0.819 – 1.24 0.93 85 849 all phecode
283 Acquired hemolytic anemias Hematopoietic 0.953 0.802 – 1.13 0.588 135 1377 all phecode
283.1 Autoimmune hemolytic anemias Hematopoietic 0.959 0.783 – 1.17 0.682 103 1059 all phecode
284 Aplastic anemia Hematopoietic 0.992 0.899 – 1.09 0.873 435 4357 all phecode
285 Other anemias Hematopoietic 1.02 1 – 1.04 0.0423 12104 121094 all phecode
285.1 Acute posthemorrhagic anemia Hematopoietic 0.988 0.875 – 1.12 0.841 271 2707 all phecode
285.2 Anemia of chronic disease Hematopoietic 1.03 0.953 – 1.11 0.461 697 6980 all phecode
285.22 Anemia in neoplastic disease Hematopoietic 0.994 0.899 – 1.1 0.914 414 4147 all phecode
286 Coagulation defects Hematopoietic 1 0.937 – 1.07 0.942 921 9218 all phecode
286.1 Congenital coagulation defects Hematopoietic 1.01 0.918 – 1.11 0.857 459 4594 all phecode
286.11 Von willebrand's disease Hematopoietic 1.03 0.841 – 1.26 0.79 96 959 all phecode
286.12
Congenital deficiency of other clotting factors
Congenital deficiency of other clotting factors (including factor VII)
 Hematopoietic 0.994 0.883 – 1.12 0.92 294 2944 all phecode
286.13 Congenital factor VIII disorder Hematopoietic 1.31 0.999 – 1.71 0.0512 63 630 all phecode
286.5
Hemorrhagic disorder due to intrinsic
Hemorrhagic disorder due to intrinsic circulating anticoagulants
 Hematopoietic 1 0.796 – 1.26 0.992 86 860 all phecode
286.7 Other and unspecified coagulation defects Hematopoietic 0.979 0.882 – 1.09 0.688 386 3867 all phecode
287 Purpura and other hemorrhagic conditions Hematopoietic 0.998 0.949 – 1.05 0.944 1652 16532 all phecode
287.1 Spontaneous ecchymoses Hematopoietic 0.834 0.695 – 1 0.05 129 1290 all phecode
287.2 Allergic purpura Hematopoietic 0.888 0.666 – 1.18 0.416 51 510 all phecode
287.3 Thrombocytopenia Hematopoietic 0.987 0.936 – 1.04 0.61 1553 15543 all phecode
287.31 Primary thrombocytopenia Hematopoietic 1.02 0.919 – 1.12 0.748 419 4195 all phecode
287.32 Secondary thrombocytopenia Hematopoietic 0.884 0.705 – 1.11 0.284 75 749 all phecode
288 Diseases of white blood cells Hematopoietic 0.991 0.958 – 1.02 0.583 3765 37672 all phecode
288.1 Decreased white blood cell count Hematopoietic 0.992 0.956 – 1.03 0.652 3168 31704 all phecode
288.11 Neutropenia Hematopoietic 0.993 0.958 – 1.03 0.701 3176 31784 all phecode
288.3 Eosinophilia Hematopoietic 0.925 0.726 – 1.18 0.53 71 709 all phecode
289 Other diseases of blood and blood-forming organs Hematopoietic 0.978 0.912 – 1.05 0.542 862 8625 all phecode
289.3
Personal history of diseases of blood and
Personal history of diseases of blood and blood-forming organs
 Hematopoietic 0.927 0.822 – 1.04 0.212 290 2897 all phecode
289.4 Lymphadenitis Hematopoietic 1 0.963 – 1.04 0.895 2602 26061 all phecode
289.5 Diseases of spleen Hematopoietic 1.03 0.941 – 1.13 0.516 516 5153 all phecode
289.8 Polycythemia, secondary Hematopoietic 1.02 0.907 – 1.15 0.725 292 2917 all phecode
289.9 Abnormality of red blood cells Hematopoietic 0.95 0.769 – 1.17 0.636 90 900 all phecode
290
Delirium dementia and amnestic and other
Delirium dementia and amnestic and other cognitive disorders
 Mental Disorders 0.954 0.91 – 0.999 0.0469 1929 19281 all phecode
290.1 Dementias Mental Disorders 0.956 0.896 – 1.02 0.169 1004 10032 all phecode
290.11 Alzheimer's disease Mental Disorders 0.89 0.806 – 0.984 0.0224 431 4307 all phecode
290.16 Vascular dementia Mental Disorders 0.902 0.782 – 1.04 0.16 201 2008 all phecode
290.2 Delirium due to conditions classified elsewhere Mental Disorders 0.964 0.889 – 1.05 0.377 650 6501 all phecode
290.3
Other persistent mental disorders due to
Other persistent mental disorders due to conditions classified elsewhere
 Mental Disorders 1.01 0.793 – 1.29 0.939 70 709 all phecode
291
Other specified nonpsychotic and/or transient
Other specified nonpsychotic and/or transient mental disorders
 Mental Disorders 0.924 0.86 – 0.993 0.0303 836 8385 all phecode
291.1
Transient mental disorders due to conditions
Transient mental disorders due to conditions classified elsewhere
 Mental Disorders 0.894 0.749 – 1.07 0.213 132 1320 all phecode
291.4
Specific nonpsychotic mental disorders due to
Specific nonpsychotic mental disorders due to brain damage
 Mental Disorders 0.941 0.834 – 1.06 0.323 286 2867 all phecode
291.8 Alteration of consciousness Mental Disorders 0.938 0.849 – 1.04 0.211 436 4376 all phecode
292 Neurological disorders Mental Disorders 0.988 0.959 – 1.02 0.437 4621 46260 all phecode
292.1 Aphasia/speech disturbance Mental Disorders 1.05 0.993 – 1.1 0.0907 1504 15074 all phecode
292.2 Mild cognitive impairment Mental Disorders 0.922 0.796 – 1.07 0.28 190 1907 all phecode
292.3 Memory loss Mental Disorders 0.978 0.905 – 1.06 0.565 696 6978 all phecode
292.4 Altered mental status Mental Disorders 0.985 0.942 – 1.03 0.494 2181 21827 all phecode
292.6 Hallucinations Mental Disorders 0.978 0.869 – 1.1 0.712 307 3073 all phecode
293 Symptoms involving head and neck Mental Disorders 0.95 0.908 – 0.993 0.0237 2078 20779 all phecode
293.1
Swelling, mass, or lump in head and neck
Swelling, mass, or lump in head and neck [Space-occupying lesion, intracranial NOS]
 Mental Disorders 1.05 0.983 – 1.13 0.141 901 9010 all phecode
295 Schizophrenia and other psychotic disorders Mental Disorders 0.971 0.904 – 1.04 0.423 841 8446 all phecode
295.1 Schizophrenia Mental Disorders 0.963 0.884 – 1.05 0.393 574 5766 all phecode
295.2 Paranoid disorders Mental Disorders 1.06 0.913 – 1.23 0.436 178 1780 all phecode
295.3 Psychosis Mental Disorders 0.947 0.806 – 1.11 0.503 169 1710 all phecode
296 Mood disorders Mental Disorders 0.99 0.972 – 1.01 0.282 12372 123822 all phecode
296.1 Bipolar Mental Disorders 0.959 0.899 – 1.02 0.196 1059 10599 all phecode
296.2 Depression Mental Disorders 0.992 0.973 – 1.01 0.399 11737 117469 all phecode
296.22 Major depressive disorder Mental Disorders 1.04 0.934 – 1.16 0.471 361 3604 all phecode
297.2 Suicide or self-inflicted injury Mental Disorders 0.978 0.873 – 1.1 0.696 311 3070 all phecode
300 Anxiety disorders Mental Disorders 0.993 0.969 – 1.02 0.573 6844 68484 all phecode
300.1 Anxiety disorder Mental Disorders 0.99 0.965 – 1.02 0.442 6324 63282 all phecode
300.11 Generalized anxiety disorder Mental Disorders 1.05 0.896 – 1.24 0.524 149 1499 all phecode
300.12 Agorophobia, social phobia, and panic disorder Mental Disorders 0.994 0.92 – 1.07 0.887 707 7065 all phecode
300.13 Phobia Mental Disorders 0.981 0.894 – 1.08 0.675 501 5013 all phecode
300.3 Obsessive-compulsive disorders Mental Disorders 0.943 0.793 – 1.12 0.509 140 1407 all phecode
300.4 Dysthymic disorder Mental Disorders 1.22 0.948 – 1.58 0.121 53 530 all phecode
300.8 Acute reaction to stress Mental Disorders 1.1 0.918 – 1.32 0.302 124 1238 all phecode
300.9 Posttraumatic stress disorder Mental Disorders 0.921 0.761 – 1.11 0.395 113 1129 all phecode
301 Personality disorders Mental Disorders 1.13 1.01 – 1.27 0.0277 334 3338 all phecode
301.2 Antisocial/borderline personality disorder Mental Disorders 1.25 1.04 – 1.51 0.0166 119 1186 all phecode
302 Sexual and gender identity disorders Mental Disorders 1.03 0.911 – 1.16 0.651 283 2845 all phecode
303 Psychogenic and somatoform disorders Mental Disorders 0.967 0.878 – 1.06 0.487 467 4679 all phecode
303.3 Psychogenic disorder Mental Disorders 0.937 0.839 – 1.05 0.249 350 3510 all phecode
303.4 Somatoform disorder Mental Disorders 1.07 0.884 – 1.29 0.501 123 1229 all phecode
304 Adjustment reaction Mental Disorders 1.03 0.914 – 1.15 0.651 293 2936 all phecode
305.2 Eating disorder Mental Disorders 1.08 0.87 – 1.34 0.488 90 900 all phecode
306 Other mental disorder Mental Disorders 1.01 0.993 – 1.02 0.369 28056 230087 all phecode
306.9 Tension headache Mental Disorders 1.01 0.904 – 1.14 0.811 315 3148 all phecode
313 Pervasive developmental disorders Mental Disorders 0.908 0.725 – 1.14 0.403 76 770 all phecode
313.3 Autism Mental Disorders 0.951 0.733 – 1.23 0.707 53 539 all phecode
315 Develomental delays and disorders Mental Disorders 1.04 0.93 – 1.16 0.505 351 3517 all phecode
315.1 Learning disorder Mental Disorders 0.998 0.85 – 1.17 0.984 161 1610 all phecode
315.2 Speech and language disorder Mental Disorders 1.06 0.855 – 1.32 0.591 88 880 all phecode
316 Substance addiction and disorders Mental Disorders 1.02 0.995 – 1.05 0.101 5313 53131 all phecode
316.1 Polyneuropathy due to drugs Mental Disorders 1.02 0.792 – 1.33 0.853 60 599 all phecode
317 Alcohol-related disorders Mental Disorders 1.02 1 – 1.04 0.0487 12696 126892 all phecode
317.1 Alcoholism Mental Disorders 1.01 0.988 – 1.03 0.393 8890 88923 all phecode
317.11 Alcoholic liver damage Mental Disorders 1.01 0.944 – 1.09 0.726 838 8392 all phecode
318 Tobacco use disorder Mental Disorders 1.02 1 – 1.03 0.0176 19359 185465 all phecode
320 Meningitis Neurological 0.969 0.879 – 1.07 0.533 444 4447 all phecode
323 Encephalitis Neurological 0.974 0.873 – 1.09 0.637 342 3422 all phecode
323.2 Acute (transverse) myelitis Neurological 1.09 0.857 – 1.39 0.481 74 739 all phecode
324 Other CNS infection and poliomyelitis Neurological 0.979 0.867 – 1.11 0.739 292 2916 all phecode
327 Sleep disorders Neurological 0.993 0.935 – 1.05 0.809 1164 11659 all phecode
327.3 Sleep apnea Neurological 0.989 0.959 – 1.02 0.48 4428 44318 all phecode
327.4 Insomnia Neurological 1.12 0.954 – 1.31 0.169 163 1660 all phecode
327.41 Organic or persistent insomnia Neurological 1.16 0.977 – 1.38 0.0898 136 1390 all phecode
331 Other cerebral degenerations Neurological 0.98 0.922 – 1.04 0.52 1142 11416 all phecode
331.1 Hydrocephalus Neurological 0.954 0.87 – 1.05 0.32 502 5014 all phecode
331.9 Cerebral degeneration, unspecified Neurological 1.02 0.928 – 1.13 0.646 430 4298 all phecode
332 Parkinson's disease Neurological 0.946 0.89 – 1.01 0.0792 1126 11254 all phecode
333
Extrapyramidal disease and abnormal movement
Extrapyramidal disease and abnormal movement disorders
 Neurological 0.955 0.89 – 1.02 0.193 894 8954 all phecode
333.1 Essential tremor Neurological 0.98 0.85 – 1.13 0.776 216 2157 all phecode
333.2 Myoclonus Neurological 1.09 0.895 – 1.34 0.379 96 958 all phecode
333.4 Torsion dystonia Neurological 1.01 0.882 – 1.15 0.927 253 2528 all phecode
334 Degenerative disease of the spinal cord Neurological 0.998 0.951 – 1.05 0.93 1812 18130 all phecode
334.1 Spinocerebellar disease Neurological 1.05 0.872 – 1.26 0.614 117 1169 all phecode
334.2 Anterior horn cell disease Neurological 0.988 0.866 – 1.13 0.863 245 2446 all phecode
335 Multiple sclerosis Neurological 0.836 0.79 – 0.885 7.08e-10 1340 13385 all phecode
337 Disorders of the autonomic nervous system Neurological 1.02 0.897 – 1.15 0.788 266 2668 all phecode
337.1 Peripheral autonomic neuropathy Neurological 0.909 0.716 – 1.15 0.431 72 719 all phecode
338 Pain Neurological 1.04 0.969 – 1.12 0.262 768 7692 all phecode
338.1 Acute pain Neurological 1.03 0.931 – 1.15 0.543 394 3937 all phecode
338.2 Chronic pain Neurological 1.06 0.956 – 1.18 0.259 380 3817 all phecode
339 Other headache syndromes Neurological 1.02 0.996 – 1.04 0.105 7819 78241 all phecode
340 Migraine Neurological 0.977 0.94 – 1.02 0.235 2860 28602 all phecode
340.1 Migrain with aura Neurological 0.955 0.83 – 1.1 0.526 212 2117 all phecode
341
Other demyelinating diseases of central nervous
Other demyelinating diseases of central nervous system
 Neurological 0.972 0.852 – 1.11 0.678 252 2535 all phecode
342 Hemiplegia Neurological 1 0.949 – 1.06 0.975 1494 14947 all phecode
343 Infantile cerebral palsy Neurological 1.16 0.981 – 1.38 0.0814 145 1450 all phecode
344 Other paralytic syndromes Neurological 1.03 0.955 – 1.12 0.415 658 6593 all phecode
345 Epilepsy, recurrent seizures, convulsions Neurological 1.01 0.977 – 1.04 0.689 5023 50270 all phecode
345.1 Epilepsy Neurological 1.01 0.945 – 1.09 0.722 866 8661 all phecode
345.11 Generalized convulsive epilepsy Neurological 1.11 1.01 – 1.22 0.0383 439 4385 all phecode
345.12 Partial epilepsy Neurological 0.912 0.807 – 1.03 0.143 277 2776 all phecode
345.3 Convulsions Neurological 1.01 0.963 – 1.05 0.812 2235 22339 all phecode
346.1
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of skull and head
 Neurological 1.16 0.981 – 1.37 0.0829 144 1438 all phecode
348 Other conditions of brain Neurological 1.02 0.951 – 1.1 0.546 778 7808 all phecode
348.2 Cerebral edema and compression of brain Neurological 1.06 0.937 – 1.2 0.351 268 2678 all phecode
348.4 Cerebral cysts Neurological 0.905 0.761 – 1.08 0.262 133 1350 all phecode
348.7 Coma Neurological 1.06 0.952 – 1.18 0.287 358 3596 all phecode
348.8 Encephalopathy, not elsewhere classified Neurological 1.06 0.93 – 1.21 0.381 249 2504 all phecode
348.9 Other conditions of brain, NOS Neurological 0.986 0.888 – 1.1 0.795 390 3899 all phecode
349
Other and unspecified disorders of the nervous
Other and unspecified disorders of the nervous system
 Neurological 0.879 0.786 – 0.983 0.0243 342 3414 all phecode
350 Abnormal movement Neurological 0.974 0.936 – 1.01 0.19 2671 26722 all phecode
350.1 Abnormal involuntary movements Neurological 0.995 0.929 – 1.07 0.879 887 8852 all phecode
350.2 Abnormality of gait Neurological 0.966 0.917 – 1.02 0.186 1596 15969 all phecode
350.3 Lack of coordination Neurological 0.956 0.859 – 1.06 0.415 363 3638 all phecode
350.6 Disturbances of sensation of smell and taste Neurological 0.766 0.576 – 1.02 0.0666 54 540 all phecode
351 Other peripheral nerve disorders Neurological 1.02 1.01 – 1.04 0.0117 12420 124321 all phecode
352 Disorders of other cranial nerves Neurological 1 0.946 – 1.06 0.981 1370 13706 all phecode
352.1 Trigeminal nerve disorders [CN5] Neurological 0.936 0.85 – 1.03 0.174 463 4638 all phecode
352.2 Facial nerve disorders [CN7] Neurological 1.02 0.954 – 1.1 0.525 880 8795 all phecode
353 Nerve root and plexus disorders Neurological 1.02 0.962 – 1.09 0.477 1131 11319 all phecode
353.1 Nerve plexus lesions Neurological 1.13 0.942 – 1.36 0.183 114 1138 all phecode
353.2 Nerve root lesions Neurological 1.05 0.799 – 1.37 0.735 57 570 all phecode
356 Hereditary and idiopathic peripheral neuropathy Neurological 0.938 0.792 – 1.11 0.461 152 1520 all phecode
357 Inflammatory and toxic neuropathy Neurological 1.04 0.98 – 1.1 0.209 1361 13648 all phecode
358 Myoneural disorders Neurological 0.95 0.823 – 1.1 0.484 211 2109 all phecode
358.1 Myasthenia gravis Neurological 0.951 0.82 – 1.1 0.505 192 1919 all phecode
359 Muscular dystrophies and other myopathies Neurological 0.972 0.884 – 1.07 0.566 465 4646 all phecode
359.1 Muscular dystrophies Neurological 0.989 0.819 – 1.2 0.911 122 1219 all phecode
359.2 Myopathy Neurological 0.981 0.881 – 1.09 0.725 360 3597 all phecode
360 Disorders of the globe Sense Organs 1.07 0.953 – 1.19 0.259 337 3367 all phecode
360.2 Progressive myopia Sense Organs 1.08 0.949 – 1.23 0.243 251 2508 all phecode
361 Retinal detachments and defects Sense Organs 1.04 1 – 1.08 0.0261 3246 32453 all phecode
361.1 Retinal detachment with retinal defect Sense Organs 1.07 1.02 – 1.14 0.0101 1389 13884 all phecode
361.2 Retinoschisis and retinal cysts Sense Organs 1.06 0.829 – 1.35 0.654 68 680 all phecode
362 Other retinal disorders Sense Organs 1.02 0.988 – 1.06 0.206 3836 38370 all phecode
362.2
Degeneration of macula and posterior pole of
Degeneration of macula and posterior pole of retina
 Sense Organs 0.991 0.948 – 1.04 0.694 2182 21813 all phecode
362.29 Macular degeneration (senile) of retina NOS Sense Organs 0.991 0.948 – 1.04 0.698 2179 21783 all phecode
362.3 Other nondiabetic retinopathy Sense Organs 1.14 0.974 – 1.33 0.102 161 1609 all phecode
362.31 Separation of retinal layers Sense Organs 1.01 0.823 – 1.24 0.933 99 990 all phecode
362.4 Retinal vascular changes and abnomalities Sense Organs 1.02 0.952 – 1.1 0.553 848 8477 all phecode
362.6 Peripheral retinal degenerations Sense Organs 0.966 0.829 – 1.13 0.66 182 1827 all phecode
362.7 Hereditary retinal dystrophies Sense Organs 0.982 0.781 – 1.24 0.88 82 812 all phecode
362.8 Retinal hemorrhage/ischemia Sense Organs 1.07 0.886 – 1.28 0.501 116 1159 all phecode
363
Chorioretinal inflammations, scars, and other
Chorioretinal inflammations, scars, and other disorders of choroid
 Sense Organs 1.02 0.869 – 1.19 0.814 170 1699 all phecode
363.3 Chorioretinal scars Sense Organs 1.13 0.889 – 1.44 0.313 69 690 all phecode
364 Corneal opacity and other disorders of cornea Sense Organs 0.958 0.884 – 1.04 0.299 647 6485 all phecode
364.1 Corneal opacity Sense Organs 1.01 0.817 – 1.24 0.948 90 910 all phecode
364.2 Corneal edema Sense Organs 1.15 0.906 – 1.45 0.254 79 800 all phecode
364.4 Corneal degenerations Sense Organs 1.12 0.964 – 1.29 0.142 201 2017 all phecode
364.41 Keratoconus Sense Organs 0.909 0.728 – 1.14 0.401 86 869 all phecode
364.5 Corneal dystrophy Sense Organs 0.864 0.748 – 0.998 0.0462 211 2109 all phecode
364.9 Cornea replaced by transplant Sense Organs 0.842 0.681 – 1.04 0.112 100 1000 all phecode
365 Glaucoma Sense Organs 1.01 0.977 – 1.04 0.642 4408 44136 all phecode
365.1 Open-angle glaucoma Sense Organs 1.06 0.999 – 1.13 0.0527 1032 10346 all phecode
365.11 Primary open angle glaucoma Sense Organs 1.06 0.995 – 1.13 0.0721 1026 10287 all phecode
365.2 Primary angle-closure glaucoma Sense Organs 0.933 0.863 – 1.01 0.083 698 6996 all phecode
366 Cataract Sense Organs 1.02 1 – 1.03 0.0198 19926 168711 all phecode
366.1 Nonsenile Cataract Sense Organs 1.04 0.814 – 1.34 0.732 69 700 all phecode
366.2 Senile cataract Sense Organs 1.02 0.998 – 1.04 0.0797 8231 81909 all phecode
366.3 Traumatic cataract Sense Organs 1.13 0.924 – 1.37 0.241 102 1019 all phecode
367
Disorders of refraction and accommodation
Disorders of refraction and accommodation; blindness and low vision
 Sense Organs 1.01 0.972 – 1.06 0.53 2408 24092 all phecode
367.1 Myopia Sense Organs 1.05 0.993 – 1.12 0.0852 1251 12519 all phecode
367.2 Astigmatism Sense Organs 0.906 0.776 – 1.06 0.208 190 1899 all phecode
367.8 Hypermetropia Sense Organs 0.87 0.761 – 0.993 0.0393 253 2530 all phecode
367.9 Blindness and low vision Sense Organs 1.01 0.932 – 1.08 0.889 719 7198 all phecode
368 Visual disturbances Sense Organs 1.02 0.982 – 1.06 0.297 2962 29648 all phecode
368.1 Amblyopia Sense Organs 1.01 0.927 – 1.11 0.776 532 5322 all phecode
368.2 Diplopia and disorders of binocular vision Sense Organs 1.02 0.949 – 1.1 0.548 727 7288 all phecode
368.3 Anisometropia Sense Organs 1.04 0.882 – 1.24 0.614 154 1548 all phecode
368.4 Visual field defects Sense Organs 0.999 0.891 – 1.12 0.988 333 3327 all phecode
368.9 Subjective visual disturbances Sense Organs 1.05 0.963 – 1.14 0.28 612 6115 all phecode
369 Infection of the eye Sense Organs 0.922 0.845 – 1.01 0.0697 553 5544 all phecode
369.2 Eye infection, viral Sense Organs 0.88 0.729 – 1.06 0.184 125 1257 all phecode
369.5 Conjunctivitis, infectious Sense Organs 0.909 0.791 – 1.04 0.178 213 2128 all phecode
370 Keratitis Sense Organs 1.04 0.922 – 1.18 0.501 286 2855 all phecode
370.1 Corneal ulcer Sense Organs 1.11 0.937 – 1.32 0.225 141 1408 all phecode
371 Inflammation of the eye Sense Organs 1.02 0.981 – 1.06 0.346 3045 30480 all phecode
371.1 Uveitis, noninfectious or NOS Sense Organs 0.979 0.892 – 1.07 0.651 482 4821 all phecode
371.3 Inflammation of eyelids Sense Organs 1.02 0.974 – 1.06 0.456 2353 23555 all phecode
372 Disorders of conjunctiva Sense Organs 1.01 0.937 – 1.09 0.81 760 7602 all phecode
374 Other disorders of eyelids Sense Organs 1.01 0.987 – 1.04 0.322 5680 56807 all phecode
374.1 Ectropion or entropion Sense Organs 0.992 0.932 – 1.06 0.805 1063 10645 all phecode
374.3 Ptosis of eyelid Sense Organs 1.04 0.989 – 1.09 0.132 1825 18232 all phecode
375 Disorders of lacrimal system Sense Organs 0.991 0.948 – 1.04 0.68 2204 22031 all phecode
375.2 Epiphora Sense Organs 1.01 0.942 – 1.08 0.782 898 8969 all phecode
376 Disorders of the orbit Sense Organs 0.974 0.788 – 1.2 0.804 86 859 all phecode
377 Disorders of optic nerve and visual pathways Sense Organs 1 0.9 – 1.12 0.95 361 3618 all phecode
377.1 Optic atrophy Sense Organs 1.34 1.01 – 1.77 0.0459 56 570 all phecode
377.3 Optic neuritis/neuropathy Sense Organs 0.978 0.811 – 1.18 0.816 125 1249 all phecode
378
Strabismus and other disorders of binocular eye
Strabismus and other disorders of binocular eye movements
 Sense Organs 0.978 0.926 – 1.03 0.425 1410 14116 all phecode
378.1 Strabismus (not specified as paralytic) Sense Organs 0.988 0.923 – 1.06 0.727 909 9082 all phecode
378.2 Nystagmus and other irregular eye movements Sense Organs 0.927 0.807 – 1.06 0.279 213 2138 all phecode
378.5 Paralytic strabismus Sense Organs 0.979 0.864 – 1.11 0.733 275 2755 all phecode
379 Other disorders of eye Sense Organs 1.03 0.992 – 1.06 0.141 3703 37063 all phecode
379.2 Disorders of vitreous body Sense Organs 1.07 1.02 – 1.14 0.0106 1367 13665 all phecode
379.3 Aphakia and other disorders of lens Sense Organs 1.04 0.991 – 1.09 0.106 1813 18134 all phecode
379.4 Anomalies of pupillary function Sense Organs 1.22 0.956 – 1.56 0.109 71 710 all phecode
379.5 Disorders of iris and ciliary body Sense Organs 0.969 0.875 – 1.07 0.535 400 4028 all phecode
379.9 Pain, swelling or discharge of eye Sense Organs 1.04 0.891 – 1.22 0.608 169 1690 all phecode
380 Disorders of external ear Sense Organs 1.01 0.928 – 1.09 0.866 642 6413 all phecode
380.1 Otitis externa Sense Organs 1.03 0.946 – 1.13 0.456 509 5107 all phecode
380.4 Impacted cerumen Sense Organs 1.03 0.927 – 1.15 0.569 362 3614 all phecode
381 Otitis media and Eustachian tube disorders Sense Organs 1.04 0.995 – 1.09 0.0787 2150 21493 all phecode
381.1 Otitis media Sense Organs 1.06 1.01 – 1.12 0.0122 1767 17668 all phecode
381.11 Suppurative and unspecified otitis media Sense Organs 1.1 1.03 – 1.18 0.00596 852 8524 all phecode
381.2 Eustachian tube disorders Sense Organs 0.981 0.848 – 1.13 0.796 193 1929 all phecode
381.3 Mastoiditis & related conditions Sense Organs 1.08 0.919 – 1.26 0.36 171 1709 all phecode
381.9 Otorrhea Sense Organs 0.999 0.883 – 1.13 0.984 281 2807 all phecode
382 Otalgia Sense Organs 0.989 0.882 – 1.11 0.856 308 3084 all phecode
383 Otosclerosis Sense Organs 0.942 0.838 – 1.06 0.311 309 3090 all phecode
384 Other disorders of tympanic membrane Sense Organs 1.03 0.974 – 1.09 0.289 1299 12991 all phecode
384.4 Perforation of tympanic membrane Sense Organs 1.05 0.987 – 1.12 0.116 1043 10432 all phecode
385 Other disorders of middle ear and mastoid Sense Organs 1.02 0.95 – 1.1 0.558 783 7837 all phecode
385.3 Cholesteatoma Sense Organs 1.03 0.95 – 1.12 0.453 607 6078 all phecode
385.5
Tympanosclerosis and middle ear disease related
Tympanosclerosis and middle ear disease related to otitis media
 Sense Organs 0.951 0.831 – 1.09 0.464 241 2409 all phecode
386
Vertiginous syndromes and other disorders of
Vertiginous syndromes and other disorders of vestibular system
 Sense Organs 0.993 0.945 – 1.04 0.773 1736 17373 all phecode
386.1 Meniere's disease Sense Organs 0.996 0.915 – 1.08 0.931 576 5768 all phecode
386.2 Peripheral or central vertigo Sense Organs 0.922 0.83 – 1.02 0.131 377 3763 all phecode
386.3 Labyrinthitis Sense Organs 1.06 0.98 – 1.14 0.154 765 7664 all phecode
386.9
Dizziness and giddiness (Light-headedness and
Dizziness and giddiness (Light-headedness and vertigo)
 Sense Organs 1 0.97 – 1.03 0.991 4582 45806 all phecode
388 Other disorders of ear Sense Organs 0.979 0.849 – 1.13 0.774 202 2017 all phecode
389 Hearing loss Sense Organs 1.02 0.991 – 1.06 0.153 4188 41944 all phecode
389.1 Sensorineural hearing loss Sense Organs 1.03 0.932 – 1.13 0.597 456 4553 all phecode
389.2 Conductive hearing loss Sense Organs 0.987 0.896 – 1.09 0.783 450 4497 all phecode
389.4 Tinnitus Sense Organs 1.05 0.955 – 1.15 0.332 513 5134 all phecode
394 Rheumatic disease of the heart valves Circulatory System 0.996 0.967 – 1.03 0.805 4899 48974 all phecode
394.2 Mitral valve disease Circulatory System 1 0.964 – 1.04 0.986 2993 29922 all phecode
394.3 Aortic valve disease Circulatory System 1.01 0.949 – 1.06 0.856 1282 12814 all phecode
394.7 Disease of tricuspid valve Circulatory System 1.01 0.947 – 1.07 0.795 1058 10566 all phecode
395 Heart valve disorders Circulatory System 1.01 0.977 – 1.04 0.607 4223 42219 all phecode
395.1 Nonrheumatic mitral valve disorders Circulatory System 0.997 0.96 – 1.04 0.878 2891 28900 all phecode
395.2 Nonrheumatic aortic valve disorders Circulatory System 1.06 0.934 – 1.19 0.387 276 2766 all phecode
395.3 Nonrheumatic tricuspid valve disorders Circulatory System 1.01 0.828 – 1.23 0.925 105 1039 all phecode
395.4 Nonrheumatic pulmonary valve disorders Circulatory System 1.06 0.867 – 1.3 0.572 97 970 all phecode
395.6 Heart valve replaced Circulatory System 1.01 0.959 – 1.07 0.684 1495 14942 all phecode
396 Abnormal heart sounds Circulatory System 1.01 0.948 – 1.08 0.755 1048 10468 all phecode
401 Hypertension Circulatory System 1.04 1.04 – 1.05 2.04e-23 73956 266957 all phecode
401.1 Essential hypertension Circulatory System 1.04 1.04 – 1.05 1.5e-23 73731 266739 all phecode
401.2 Hypertensive heart and/or renal disease Circulatory System 1.06 1.01 – 1.11 0.0129 1898 19031 all phecode
401.21 Hypertensive heart disease Circulatory System 0.962 0.866 – 1.07 0.477 370 3699 all phecode
401.22 Hypertensive chronic kidney disease Circulatory System 1.08 1.03 – 1.14 0.00351 1543 15483 all phecode
401.3 Other hypertensive complications Circulatory System 0.981 0.825 – 1.17 0.825 144 1438 all phecode
402
Elevated blood pressure reading without
Elevated blood pressure reading without diagnosis of hypertension
 Circulatory System 1.06 1 – 1.11 0.0414 1479 14786 all phecode
411 Ischemic Heart Disease Circulatory System 1.04 1.03 – 1.05 1.28e-09 31245 210714 all phecode
411.1 Unstable angina (intermediate coronary syndrome) Circulatory System 1.05 1.02 – 1.08 0.00157 5152 51498 all phecode
411.2 Myocardial infarction Circulatory System 1.04 1.02 – 1.06 2.6e-05 11950 112699 all phecode
411.3 Angina pectoris Circulatory System 1.04 1.02 – 1.06 9.28e-07 15888 143745 all phecode
411.4 Coronary atherosclerosis Circulatory System 1.04 1.03 – 1.06 1.43e-07 20171 154621 all phecode
411.41 Aneurysm and dissection of heart Circulatory System 0.976 0.903 – 1.05 0.54 700 6997 all phecode
411.8
Other chronic ischemic heart disease
Other chronic ischemic heart disease, unspecified
 Circulatory System 1.04 1.02 – 1.06 2.54e-06 15290 131798 all phecode
411.9
Other acute and subacute forms of ischemic
Other acute and subacute forms of ischemic heart disease
 Circulatory System 0.997 0.94 – 1.06 0.926 1218 12166 all phecode
414 Other forms of chronic heart disease Circulatory System 1.09 1.04 – 1.14 0.000441 1823 18228 all phecode
414.2 ASCVD Circulatory System 0.944 0.738 – 1.21 0.645 72 719 all phecode
415 Pulmonary heart disease Circulatory System 0.997 0.967 – 1.03 0.872 4476 44810 all phecode
415.11 Pulmonary embolism and infarction, acute Circulatory System 0.841 0.663 – 1.07 0.155 75 750 all phecode
415.2 Chronic pulmonary heart disease Circulatory System 1.05 0.962 – 1.14 0.289 601 6002 all phecode
415.21 Primary pulmonary hypertension Circulatory System 1.05 0.957 – 1.16 0.288 448 4475 all phecode
416 Cardiomegaly Circulatory System 1.01 0.97 – 1.05 0.673 2680 26793 all phecode
418 Nonspecific chest pain Circulatory System 1.01 1 – 1.02 0.0548 28599 270106 all phecode
418.1 Precordial pain Circulatory System 1.04 1 – 1.07 0.0318 3551 35541 all phecode
420 Carditis Circulatory System 0.94 0.899 – 0.983 0.00637 2106 21053 all phecode
420.1 Myocarditis Circulatory System 0.966 0.8 – 1.17 0.715 127 1267 all phecode
420.2 Pericarditis Circulatory System 0.926 0.876 – 0.979 0.00711 1338 13371 all phecode
420.21 Acute pericarditis Circulatory System 0.92 0.801 – 1.06 0.236 223 2227 all phecode
420.22 Chronic pericarditis Circulatory System 0.963 0.795 – 1.17 0.704 113 1129 all phecode
420.3 Endocarditis Circulatory System 0.988 0.915 – 1.07 0.758 719 7194 all phecode
425 Cardiomyopathy Circulatory System 1.03 0.973 – 1.09 0.303 1271 12699 all phecode
425.1 Primary/intrinsic cardiomyopathies Circulatory System 1.05 0.988 – 1.11 0.122 1236 12349 all phecode
425.11 Hypertrophic obstructive cardiomyopathy Circulatory System 0.963 0.801 – 1.16 0.688 133 1329 all phecode
425.12 Other hypertrophic cardiomyopathy Circulatory System 0.871 0.741 – 1.02 0.0948 163 1629 all phecode
425.8 Other cardiomyopathy Circulatory System 0.791 0.6 – 1.04 0.0958 60 600 all phecode
426 Cardiac conduction disorders Circulatory System 1 0.98 – 1.03 0.729 6910 69146 all phecode
426.2 Atrioventricular [AV] block Circulatory System 0.981 0.938 – 1.03 0.413 2114 21162 all phecode
426.21 First degree AV block Circulatory System 1 0.939 – 1.07 0.935 986 9867 all phecode
426.23 Second degree AV block Circulatory System 0.996 0.906 – 1.1 0.94 452 4515 all phecode
426.24 Atrioventricular block, complete Circulatory System 0.991 0.91 – 1.08 0.83 587 5868 all phecode
426.25 Other heart block Circulatory System 0.813 0.677 – 0.976 0.0267 131 1318 all phecode
426.3 Bundle branch block Circulatory System 1.01 0.979 – 1.05 0.433 3336 33359 all phecode
426.31 Right bundle branch block Circulatory System 0.987 0.936 – 1.04 0.628 1494 14933 all phecode
426.32 Left bundle branch block Circulatory System 1.03 0.985 – 1.09 0.18 1750 17503 all phecode
426.4 Anomalous atrioventricular excitation Circulatory System 0.926 0.809 – 1.06 0.262 233 2328 all phecode
426.8 Other cardiac conduction disorders Circulatory System 1.02 0.793 – 1.32 0.859 60 600 all phecode
426.9 Cardiac pacemaker/device in situ Circulatory System 1.01 0.966 – 1.05 0.748 2475 24774 all phecode
426.91 Cardiac pacemaker in situ Circulatory System 1.01 0.963 – 1.05 0.787 2274 22762 all phecode
427 Cardiac dysrhythmias Circulatory System 0.993 0.979 – 1.01 0.275 24207 206016 all phecode
427.1 Paroxysmal tachycardia, unspecified Circulatory System 1.03 0.992 – 1.07 0.13 3199 32017 all phecode
427.11 Paroxysmal supraventricular tachycardia Circulatory System 1.02 0.978 – 1.06 0.344 2344 23474 all phecode
427.12 Paroxysmal ventricular tachycardia Circulatory System 1.08 1.01 – 1.16 0.0231 936 9365 all phecode
427.2 Atrial fibrillation and flutter Circulatory System 0.994 0.977 – 1.01 0.481 14628 133501 all phecode
427.3 Other specified cardiac dysrhythmias Circulatory System 1 0.967 – 1.04 0.892 3228 32281 all phecode
427.4 Cardiac arrest and ventricular fibrillation Circulatory System 0.98 0.924 – 1.04 0.515 1193 11915 all phecode
427.41 Ventricular fibrillation and flutter Circulatory System 0.973 0.871 – 1.09 0.626 344 3437 all phecode
427.42 Cardiac arrest Circulatory System 0.982 0.92 – 1.05 0.583 990 9890 all phecode
427.5 Arrhythmia (cardiac) NOS Circulatory System 0.969 0.908 – 1.04 0.355 952 9541 all phecode
427.6 Premature beats Circulatory System 0.994 0.909 – 1.09 0.891 535 5358 all phecode
427.61 Supraventricular premature beats Circulatory System 0.98 0.812 – 1.18 0.831 117 1168 all phecode
427.7 Tachycardia NOS Circulatory System 0.993 0.95 – 1.04 0.739 2185 21865 all phecode
427.8 Sinoatrial node dysfunction (Bradycardia) Circulatory System 0.987 0.89 – 1.09 0.811 402 4029 all phecode
427.9 Palpitations Circulatory System 0.986 0.954 – 1.02 0.413 3811 38105 all phecode
428 Congestive heart failure; nonhypertensive Circulatory System 1.01 0.986 – 1.04 0.331 5605 56018 all phecode
428.1 Congestive heart failure (CHF) NOS Circulatory System 1.04 0.992 – 1.08 0.111 2111 21108 all phecode
428.2 Heart failure NOS Circulatory System 1.01 0.982 – 1.04 0.431 4455 44524 all phecode
429
Ill-defined descriptions and complications of
Ill-defined descriptions and complications of heart disease
 Circulatory System 1.04 0.961 – 1.12 0.357 716 7168 all phecode
429.1 Heart transplant/surgery Circulatory System 1.18 0.912 – 1.52 0.21 64 639 all phecode
429.2 Abnormal function study of cardiovascular system Circulatory System 1.02 0.933 – 1.11 0.665 522 5211 all phecode
429.3 Symptoms involving cardiovascular system Circulatory System 1.09 0.941 – 1.26 0.258 196 1978 all phecode
430 Intracranial hemorrhage Circulatory System 1.01 0.963 – 1.06 0.693 1883 18825 all phecode
430.1 Subarachnoid hemorrhage Circulatory System 0.959 0.894 – 1.03 0.246 836 8353 all phecode
430.2 Intracerebral hemorrhage Circulatory System 1.04 0.963 – 1.12 0.332 765 7656 all phecode
430.3 Subdural hemorrhage Circulatory System 1.01 0.892 – 1.15 0.86 267 2667 all phecode
433 Cerebrovascular disease Circulatory System 1.03 1.01 – 1.06 0.00357 8749 87456 all phecode
433.1 Occlusion and stenosis of precerebral arteries Circulatory System 1.03 0.967 – 1.09 0.401 1185 11825 all phecode
433.12 Cerebral atherosclerosis Circulatory System 1.03 0.9 – 1.17 0.688 227 2267 all phecode
433.2 Occlusion of cerebral arteries Circulatory System 1.02 0.992 – 1.06 0.151 4233 42320 all phecode
433.21
Cerebral artery occlusion, with cerebral
Cerebral artery occlusion, with cerebral infarction
 Circulatory System 1.06 1 – 1.11 0.0319 1680 16794 all phecode
433.3 Cerebral ischemia Circulatory System 1.02 0.982 – 1.06 0.309 2895 28989 all phecode
433.31 Transient cerebral ischemia Circulatory System 1.02 0.977 – 1.07 0.356 2135 21379 all phecode
433.5 Cerebral aneurysm Circulatory System 1.09 0.984 – 1.21 0.0984 394 3939 all phecode
433.8 Late effects of cerebrovascular disease Circulatory System 1.03 0.968 – 1.09 0.388 1279 12783 all phecode
440 Atherosclerosis Circulatory System 1.11 1.05 – 1.18 0.000112 1380 13822 all phecode
440.1 Atherosclerosis of renal artery Circulatory System 1.14 0.943 – 1.38 0.174 113 1129 all phecode
440.2 Atherosclerosis of the extremities Circulatory System 1.11 1.04 – 1.2 0.00338 805 8070 all phecode
440.9 Atherosclerosis of aorta Circulatory System 1.06 0.938 – 1.19 0.364 287 2867 all phecode
441 Vascular insufficiency of intestine Circulatory System 1 0.923 – 1.09 0.957 614 6154 all phecode
441.1 Acute vascular insufficiency of intestine Circulatory System 0.941 0.832 – 1.06 0.335 283 2827 all phecode
442 Other aneurysm Circulatory System 0.989 0.943 – 1.04 0.64 1892 18959 all phecode
442.1 Aortic aneurysm Circulatory System 0.987 0.935 – 1.04 0.637 1458 14625 all phecode
442.11 Abdominal aortic aneurysm Circulatory System 1 0.937 – 1.07 0.93 931 9341 all phecode
442.2 Aneurysm of iliac artery Circulatory System 0.904 0.744 – 1.1 0.314 102 1019 all phecode
442.3 Aneurysm of artery of lower extremity Circulatory System 1.07 0.916 – 1.25 0.398 169 1696 all phecode
442.4 Arterial dissection Circulatory System 0.962 0.726 – 1.27 0.787 54 549 all phecode
442.8 Aneurysm of other specified artery Circulatory System 0.953 0.825 – 1.1 0.514 203 2028 all phecode
443 Peripheral vascular disease Circulatory System 1.06 1.03 – 1.1 0.000279 3921 39273 all phecode
443.1 Raynaud's syndrome Circulatory System 0.97 0.912 – 1.03 0.321 1145 11438 all phecode
443.7
Peripheral angiopathy in diseases classified
Peripheral angiopathy in diseases classified elsewhere
 Circulatory System 1.36 1.23 – 1.51 2.89e-09 384 3878 all phecode
443.8 Other specified peripheral vascular diseases Circulatory System 1.05 1.02 – 1.09 0.00357 3686 36906 all phecode
443.9 Peripheral vascular disease, unspecified Circulatory System 1.09 1.05 – 1.14 2.08e-05 2579 25846 all phecode
444 Arterial embolism and thrombosis Circulatory System 1.07 1.01 – 1.15 0.0348 922 9251 all phecode
444.1
Arterial embolism and thrombosis of lower
Arterial embolism and thrombosis of lower extremity artery
 Circulatory System 1.18 1.08 – 1.29 0.000188 554 5552 all phecode
446 Polyarteritis nodosa and allied conditions Circulatory System 1.05 0.974 – 1.12 0.214 822 8226 all phecode
446.4 Wegener's granulomatosis Circulatory System 1.13 0.975 – 1.31 0.104 188 1878 all phecode
446.5 Giant cell arteritis Circulatory System 1 0.902 – 1.11 0.997 388 3879 all phecode
446.9 Arteritis NOS Circulatory System 1.03 0.899 – 1.17 0.705 239 2400 all phecode
447 Other disorders of arteries and arterioles Circulatory System 1.08 1.02 – 1.14 0.00936 1327 13316 all phecode
447.1 Stricture of artery Circulatory System 1.16 1.08 – 1.25 2.46e-05 868 8712 all phecode
448 Disease of capillaries Circulatory System 1.04 0.879 – 1.23 0.638 142 1420 all phecode
450 Noninfectious disorders of lymphatic channels Circulatory System 0.984 0.91 – 1.06 0.697 704 7034 all phecode
451 Phlebitis and thrombophlebitis Circulatory System 1.01 0.98 – 1.05 0.445 3955 39683 all phecode
451.2
Phlebitis and thrombophlebitis of lower
Phlebitis and thrombophlebitis of lower extremities
 Circulatory System 1.01 0.977 – 1.05 0.539 3683 36977 all phecode
452 Other venous embolism and thrombosis Circulatory System 0.953 0.875 – 1.04 0.271 564 5645 all phecode
454 Varicose veins Circulatory System 0.974 0.956 – 0.993 0.00871 11180 112047 all phecode
454.1 Varicose veins of lower extremity Circulatory System 0.969 0.95 – 0.987 0.00107 11503 115272 all phecode
454.11 Varicose veins of lower extremity, symptomtic Circulatory System 0.914 0.841 – 0.992 0.0321 624 6325 all phecode
455 Hemorrhoids Circulatory System 0.998 0.985 – 1.01 0.822 23452 234585 all phecode
456 Chronic venous insufficiency [CVI] Circulatory System 0.901 0.774 – 1.05 0.18 184 1868 all phecode
457
Encounter for long-term (current) use of
Encounter for long-term (current) use of anticoagulants, antithrombotics, aspirin
 Circulatory System 0.989 0.797 – 1.23 0.918 97 967 all phecode
458 Hypotension Circulatory System 1.01 0.985 – 1.04 0.376 5769 57772 all phecode
458.1 Orthostatic hypotension Circulatory System 1.03 0.975 – 1.09 0.285 1335 13376 all phecode
458.2 Iatrogenic hypotension Circulatory System 1.03 0.899 – 1.17 0.711 235 2348 all phecode
458.9 Hypotension NOS Circulatory System 1.02 0.982 – 1.05 0.345 3494 35005 all phecode
459 Other disorders of circulatory system Circulatory System 1 0.987 – 1.02 0.686 16268 160790 all phecode
459.1 Hemorrhage NOS Circulatory System 0.941 0.789 – 1.12 0.5 142 1420 all phecode
459.9 Circulatory disease NEC Circulatory System 1 0.989 – 1.02 0.567 16103 159422 all phecode
464 Acute sinusitis Respiratory 1.19 1.03 – 1.38 0.0175 196 1957 all phecode
465
Acute upper respiratory infections of multiple
Acute upper respiratory infections of multiple or unspecified sites
 Respiratory 1.05 1 – 1.09 0.0434 2283 22827 all phecode
465.2 Acute pharyngitis Respiratory 1.03 0.959 – 1.11 0.418 835 8348 all phecode
465.4 Acute laryngitis and tracheitis Respiratory 0.983 0.835 – 1.16 0.836 165 1649 all phecode
470 Septal Deviations/Turbinate Hypertrophy Respiratory 0.999 0.97 – 1.03 0.972 4654 46553 all phecode
471 Nasal polyps Respiratory 1.06 1.02 – 1.1 0.00195 3297 32973 all phecode
472 Chronic pharyngitis and nasopharyngitis Respiratory 1.01 0.94 – 1.07 0.88 960 9594 all phecode
473 Diseases of the larynx and vocal cords Respiratory 1.01 0.969 – 1.05 0.672 2554 25548 all phecode
473.1 Chronic laryngitis Respiratory 0.89 0.728 – 1.09 0.254 104 1038 all phecode
473.3 Paralysis/spasm of vocal cords or larynx Respiratory 0.972 0.854 – 1.11 0.663 264 2647 all phecode
473.4 Voice disturbance Respiratory 0.983 0.923 – 1.05 0.604 1080 10789 all phecode
474 Acute and chronic tonsillitis Respiratory 1.01 0.959 – 1.06 0.789 1772 17710 all phecode
474.1 Acute tonsillitis Respiratory 1.03 0.949 – 1.13 0.438 549 5486 all phecode
474.2 Chronic tonsillitis and adenoiditis Respiratory 1.03 0.969 – 1.09 0.347 1122 11199 all phecode
475 Chronic sinusitis Respiratory 1.03 0.986 – 1.07 0.198 2589 25882 all phecode
476 Allergic rhinitis Respiratory 0.969 0.91 – 1.03 0.336 1055 10563 all phecode
477 Epistaxis or throat hemorrhage Respiratory 0.987 0.947 – 1.03 0.524 2447 24452 all phecode
478 Throat pain Respiratory 0.939 0.845 – 1.04 0.246 377 3789 all phecode
479 Other upper respiratory disease Respiratory 1.01 0.974 – 1.04 0.714 4074 40737 all phecode
480 Pneumonia Respiratory 0.981 0.962 – 1 0.0689 10336 103397 all phecode
480.1 Bacterial pneumonia Respiratory 0.972 0.948 – 0.997 0.0263 6637 66410 all phecode
480.11 Pneumococcal pneumonia Respiratory 0.969 0.943 – 0.995 0.0197 5883 58863 all phecode
480.12 Pseudomonal pneumonia Respiratory 1.08 0.876 – 1.34 0.456 93 929 all phecode
480.2 Viral pneumonia Respiratory 1.15 0.904 – 1.47 0.251 72 720 all phecode
480.3 Pneumonia due to fungus (mycoses) Respiratory 1.04 0.857 – 1.27 0.668 99 989 all phecode
480.5 Bronchopneumonia and lung abscess Respiratory 1.01 0.94 – 1.09 0.766 794 7951 all phecode
481 Influenza Respiratory 1.08 0.962 – 1.2 0.203 328 3278 all phecode
483 Acute bronchitis and bronchiolitis Respiratory 1.19 1.03 – 1.38 0.0183 193 1930 all phecode
495 Asthma Respiratory 1.03 1.02 – 1.04 3.24e-06 25689 250406 all phecode
495.2 Asthma with exacerbation Respiratory 1.01 0.892 – 1.15 0.833 250 2510 all phecode
496 Chronic airway obstruction Respiratory 1.02 0.998 – 1.04 0.0809 10424 101546 all phecode
496.1 Emphysema Respiratory 1.01 0.958 – 1.06 0.786 1743 17438 all phecode
496.2 Chronic bronchitis Respiratory 1.01 0.968 – 1.04 0.774 2947 29498 all phecode
496.21 Obstructive chronic bronchitis Respiratory 1.01 0.97 – 1.05 0.662 2706 27081 all phecode
496.3 Bronchiectasis Respiratory 0.984 0.939 – 1.03 0.517 1885 18859 all phecode
497 Bronchitis Respiratory 0.928 0.854 – 1.01 0.0742 626 6267 all phecode
500 Lung disease due to external agents Respiratory 0.886 0.8 – 0.982 0.0209 412 4099 all phecode
500.1 Extrinsic allergic alveolitis Respiratory 0.915 0.727 – 1.15 0.451 79 784 all phecode
500.2 Pneumoconiosis Respiratory 0.863 0.755 – 0.988 0.0322 243 2409 all phecode
501 Pneumonitis due to inhalation of food or vomitus Respiratory 0.988 0.911 – 1.07 0.762 656 6557 all phecode
502 Postinflammatory pulmonary fibrosis Respiratory 1.01 0.946 – 1.08 0.737 917 9193 all phecode
503 Pulmonary congestion and hypostasis Respiratory 1.01 0.924 – 1.11 0.779 508 5079 all phecode
504 Other alveolar and parietoalveolar pneumonopathy Respiratory 1.01 0.898 – 1.13 0.909 328 3280 all phecode
505 Other pulmonary inflamation or edema Respiratory 1.01 0.782 – 1.31 0.916 61 610 all phecode
506 Empyema and pneumothorax Respiratory 1.01 0.948 – 1.07 0.81 1133 11362 all phecode
507 Pleurisy; pleural effusion Respiratory 0.978 0.953 – 1 0.0867 6419 64252 all phecode
508
Pulmonary collapse; interstitial and
Pulmonary collapse; interstitial and compensatory emphysema
 Respiratory 0.973 0.929 – 1.02 0.234 1996 19947 all phecode
509 Respiratory failure, insufficiency, arrest Respiratory 1.03 0.987 – 1.07 0.188 2599 26031 all phecode
509.1 Respiratory failure Respiratory 1.03 0.983 – 1.08 0.222 2068 20708 all phecode
509.2 Respiratory insufficiency Respiratory 1.02 0.973 – 1.07 0.384 1806 18106 all phecode
509.5 Respiratory arrest Respiratory 0.971 0.821 – 1.15 0.731 143 1429 all phecode
509.8
Dependence on respirator [Ventilator] or
Dependence on respirator [Ventilator] or supplemental oxygen
 Respiratory 1.05 0.95 – 1.17 0.329 386 3863 all phecode
510 Other diseases of lung Respiratory 1.02 0.947 – 1.1 0.595 755 7554 all phecode
512 Other symptoms of respiratory system Respiratory 1.01 0.984 – 1.03 0.59 9031 90349 all phecode
512.1 Wheezing Respiratory 0.949 0.824 – 1.09 0.467 220 2196 all phecode
512.2 Painful respiration Respiratory 1.08 0.935 – 1.24 0.307 207 2075 all phecode
512.7 Shortness of breath Respiratory 1.01 0.982 – 1.04 0.54 5842 58498 all phecode
512.8 Cough Respiratory 0.991 0.954 – 1.03 0.651 2866 28642 all phecode
512.9 Other dyspnea Respiratory 0.999 0.933 – 1.07 0.97 914 9124 all phecode
513 Respiratory abnormalities Respiratory 1.08 0.994 – 1.17 0.0697 611 6112 all phecode
513.3 Hypoventilation Respiratory 0.911 0.725 – 1.14 0.424 83 830 all phecode
513.4 Hyperventilation Respiratory 1.14 1.01 – 1.28 0.0384 278 2778 all phecode
513.8 Disorders of diaphragm Respiratory 1.17 0.992 – 1.38 0.0621 153 1538 all phecode
514 Abnormal findings examination of lungs Respiratory 1.01 0.964 – 1.05 0.804 2465 24673 all phecode
516 Abnormal sputum Respiratory 0.987 0.944 – 1.03 0.562 2132 21335 all phecode
516.1 Hemoptysis Respiratory 0.99 0.947 – 1.04 0.678 2073 20745 all phecode
519
Other diseases of respiratory system, not
Other diseases of respiratory system, not elsewhere classified
 Respiratory 1.01 0.987 – 1.03 0.43 9366 93681 all phecode
519.2 Respiratory complications Respiratory 1.02 0.908 – 1.14 0.783 327 3279 all phecode
519.8 Other diseases of respiratory system, NEC Respiratory 1.01 0.988 – 1.03 0.357 8853 88522 all phecode
519.9
Symptoms involving respiratory system and other
Symptoms involving respiratory system and other chest symptoms
 Respiratory 0.959 0.85 – 1.08 0.493 303 3049 all phecode
520 Disorders of tooth development Digestive 0.975 0.932 – 1.02 0.283 2038 20354 all phecode
520.1 Hereditary disturbances in tooth structure Digestive 1.02 0.764 – 1.36 0.9 53 530 all phecode
520.2 Disturbances in tooth eruption Digestive 0.973 0.933 – 1.02 0.209 2356 23539 all phecode
521 Diseases of hard tissues of teeth Digestive 1.03 0.997 – 1.07 0.0738 3016 30245 all phecode
521.1 Dental caries Digestive 1.04 1 – 1.08 0.0419 3026 30353 all phecode
522 Diseases of pulp and periapical tissues Digestive 1.01 0.96 – 1.06 0.765 1774 17750 all phecode
522.5 Periapical abscess Digestive 1.02 0.964 – 1.09 0.448 1172 11731 all phecode
523 Gingival and periodontal diseases Digestive 0.993 0.945 – 1.04 0.796 1681 16812 all phecode
523.1 Gingivitis Digestive 1.16 0.948 – 1.41 0.151 113 1127 all phecode
523.3 Periodontitis (acute or chronic) Digestive 1 0.943 – 1.06 0.968 1165 11650 all phecode
523.31 Acute periodontitis Digestive 0.989 0.913 – 1.07 0.791 666 6667 all phecode
523.32 Chronic periodontitis Digestive 1 0.921 – 1.09 0.924 560 5594 all phecode
524 Dentofacial anomalies, including malocclusion Digestive 0.941 0.839 – 1.06 0.298 331 3307 all phecode
524.3 Anomalies of tooth position/malocclusion Digestive 0.97 0.861 – 1.09 0.614 305 3046 all phecode
525
Other diseases of the teeth and supporting
Other diseases of the teeth and supporting structures
 Digestive 1 0.963 – 1.04 0.935 2668 26728 all phecode
525.2 Atrophy of edentulous alveolar ridge Digestive 0.893 0.7 – 1.14 0.364 72 720 all phecode
526 Diseases of the jaws Digestive 1.01 0.94 – 1.08 0.859 928 9279 all phecode
526.1 Cysts of the jaws Digestive 0.979 0.873 – 1.1 0.719 329 3289 all phecode
526.3 Anomalies of jaw size/symmetry Digestive 0.934 0.721 – 1.21 0.604 61 610 all phecode
526.4 Temporomandibular joint disorders Digestive 1.09 0.956 – 1.25 0.192 240 2406 all phecode
526.41 Temporomandibular joint disorder, unspecified Digestive 1.09 0.954 – 1.25 0.202 233 2336 all phecode
526.5 Inflammatory conditions of jaw Digestive 1.03 0.849 – 1.25 0.754 110 1098 all phecode
526.9 Jaw disease NOS Digestive 0.929 0.812 – 1.06 0.288 233 2329 all phecode
527 Diseases of the salivary glands Digestive 1.02 0.941 – 1.1 0.663 694 6943 all phecode
527.1 Hypertrophy of salivary gland Digestive 1.24 0.997 – 1.55 0.0529 84 838 all phecode
527.2 Sialoadenitis Digestive 1.02 0.913 – 1.13 0.775 365 3656 all phecode
527.7 Disturbance of salivary secretion Digestive 0.915 0.701 – 1.2 0.516 62 619 all phecode
527.8 Other specified diseases of the salivary glands Digestive 0.916 0.76 – 1.1 0.357 120 1200 all phecode
528
Diseases of the oral soft tissues, excluding
Diseases of the oral soft tissues, excluding lesions specific for gingiva and tongue
 Digestive 1.03 0.992 – 1.06 0.14 3873 38741 all phecode
528.1 Stomatitis and mucositis Digestive 0.981 0.892 – 1.08 0.691 468 4675 all phecode
528.11 Stomatitis and mucositis (ulcerative) Digestive 0.971 0.875 – 1.08 0.582 389 3884 all phecode
528.12 Oral aphthae Digestive 1.03 0.827 – 1.29 0.786 84 840 all phecode
528.3 Cellulitis and abscess of oral soft tissues Digestive 0.977 0.84 – 1.14 0.766 179 1790 all phecode
528.4 Cysts of oral soft tissues Digestive 0.952 0.782 – 1.16 0.621 122 1219 all phecode
528.41 Cyst of the salivary gland Digestive 1.06 0.846 – 1.32 0.626 94 940 all phecode
528.5 Diseases of lips Digestive 1.02 0.941 – 1.1 0.677 681 6813 all phecode
528.6 Leukoplakia of oral mucosa Digestive 1.06 0.943 – 1.19 0.328 308 3079 all phecode
528.7 Sialolithiasis Digestive 1.06 0.946 – 1.19 0.315 314 3138 all phecode
529 Diseases and other conditions of the tongue Digestive 0.986 0.93 – 1.05 0.647 1232 12312 all phecode
529.1 Glossitis Digestive 1.03 0.916 – 1.16 0.598 299 2986 all phecode
530 Diseases of esophagus Digestive 1 0.991 – 1.01 0.723 33453 279172 all phecode
530.1 Esophagitis, GERD and related diseases Digestive 1 0.992 – 1.02 0.517 31253 272429 all phecode
530.11 GERD Digestive 1.01 0.993 – 1.02 0.35 22633 225879 all phecode
530.12 Ulcer of esophagus Digestive 1 0.972 – 1.03 0.989 5203 52068 all phecode
530.14 Reflux esophagitis Digestive 0.997 0.977 – 1.02 0.762 10444 104493 all phecode
530.2 Esophageal bleeding (varices/hemorrhage) Digestive 1.01 0.964 – 1.07 0.607 1681 16808 all phecode
530.3 Stricture and stenosis of esophagus Digestive 0.983 0.937 – 1.03 0.476 1869 18684 all phecode
530.5 Disorders of esophageal motility Digestive 0.945 0.871 – 1.03 0.175 635 6365 all phecode
530.6 Diverticulum of esophagus, acquired Digestive 0.849 0.718 – 1 0.0568 153 1527 all phecode
530.7 Gastroesophageal laceration-hemorrhage syndrome Digestive 1.04 0.928 – 1.16 0.528 341 3416 all phecode
530.9 Heartburn Digestive 1 0.957 – 1.05 0.956 2087 20881 all phecode
531 Peptic ulcer (excl. esophageal) Digestive 1.02 0.993 – 1.04 0.16 7103 71066 all phecode
531.1 Hemorrhage from gastrointestinal ulcer Digestive 1.01 0.93 – 1.09 0.837 637 6374 all phecode
531.2 Gastric ulcer Digestive 1.04 1.01 – 1.08 0.0117 4091 40941 all phecode
531.3 Duodenal ulcer Digestive 1.02 0.983 – 1.06 0.28 2999 30005 all phecode
531.4 Peptic ulcer, site unspecified Digestive 0.954 0.864 – 1.05 0.348 427 4268 all phecode
532 Dysphagia Digestive 0.98 0.955 – 1.01 0.127 6427 64329 all phecode
535 Gastritis and duodenitis Digestive 1.01 0.995 – 1.02 0.258 28078 261548 all phecode
535.1 Acute gastritis Digestive 1.05 0.99 – 1.11 0.103 1183 11833 all phecode
535.2 Atrophic gastritis Digestive 1.03 0.927 – 1.15 0.572 370 3687 all phecode
535.6 Duodenitis Digestive 0.997 0.973 – 1.02 0.776 7592 75928 all phecode
535.8 Other specified gastritis Digestive 1 0.981 – 1.03 0.725 8071 80763 all phecode
535.9 Gastritis and duodenitis, NOS Digestive 1.13 0.933 – 1.36 0.217 120 1191 all phecode
536.8
Dyspepsia and other specified disorders of
Dyspepsia and other specified disorders of function of stomach
 Digestive 1.04 0.918 – 1.17 0.551 259 2576 all phecode
537 Other disorders of stomach and duodenum Digestive 1 0.968 – 1.04 0.88 3391 33907 all phecode
540 Appendiceal conditions Digestive 0.999 0.962 – 1.04 0.941 3088 30890 all phecode
540.1 Appendicitis Digestive 0.991 0.954 – 1.03 0.632 2895 28963 all phecode
540.11 Acute appendicitis Digestive 0.987 0.948 – 1.03 0.516 2601 26019 all phecode
550 Abdominal hernia Digestive 1 0.993 – 1.01 0.5 45429 282640 all phecode
550.1 Inguinal hernia Digestive 1.01 0.992 – 1.03 0.29 15794 123247 all phecode
550.2 Diaphragmatic hernia Digestive 1 0.988 – 1.01 0.952 26494 238953 all phecode
550.3 Femoral hernia Digestive 0.96 0.886 – 1.04 0.328 651 6504 all phecode
550.4 Umbilical hernia Digestive 0.964 0.932 – 0.998 0.0357 3705 37072 all phecode
550.5 Ventral hernia Digestive 0.995 0.961 – 1.03 0.799 3435 34338 all phecode
555
Inflammatory bowel disease and other
Inflammatory bowel disease and other gastroenteritis and colitis
 Digestive 0.963 0.934 – 0.993 0.0173 4444 44442 all phecode
555.1 Regional enteritis Digestive 1.01 0.96 – 1.06 0.731 1734 17340 all phecode
555.2 Ulcerative colitis Digestive 0.944 0.91 – 0.979 0.00202 3178 31786 all phecode
555.21 Ulcerative colitis (chronic) Digestive 0.889 0.813 – 0.973 0.0108 538 5382 all phecode
556 Ulceration of the lower GI tract Digestive 1 0.94 – 1.07 0.978 1055 10592 all phecode
556.1 Ulceration of intestine Digestive 1 0.926 – 1.09 0.951 670 6714 all phecode
557 Intestinal malabsorption (non-celiac) Digestive 1.04 0.928 – 1.17 0.479 299 2987 all phecode
557.1 Celiac disease Digestive 0.978 0.932 – 1.03 0.375 1837 18388 all phecode
558 Noninfectious gastroenteritis Digestive 1.01 0.995 – 1.03 0.176 15492 155105 all phecode
559 Ileostomy status Digestive 0.946 0.899 – 0.996 0.0332 1656 16541 all phecode
560 Intestinal obstruction without mention of hernia Digestive 0.97 0.939 – 1 0.0709 3936 39337 all phecode
560.1 Paralytic ileus Digestive 0.975 0.891 – 1.07 0.584 523 5231 all phecode
560.2 Impaction of intestine Digestive 0.948 0.835 – 1.08 0.414 268 2671 all phecode
560.3 Peritoneal or intestinal adhesions Digestive 0.936 0.871 – 1 0.067 832 8317 all phecode
560.4 Other intestinal obstruction Digestive 0.974 0.94 – 1.01 0.146 3358 33550 all phecode
561 Symptoms involving digestive system Digestive 1 0.989 – 1.02 0.561 15772 157686 all phecode
561.1 Diarrhea Digestive 0.879 0.799 – 0.968 0.00852 466 4653 all phecode
561.2 Flatulence Digestive 1.01 0.963 – 1.06 0.628 1687 16859 all phecode
562 Diverticulosis and diverticulitis Digestive 1.01 0.994 – 1.02 0.3 26714 211692 all phecode
562.1 Diverticulosis Digestive 1.01 0.994 – 1.02 0.315 26672 211642 all phecode
563 Constipation Digestive 1.01 0.987 – 1.03 0.457 10314 103140 all phecode
564 Functional digestive disorders Digestive 1.01 0.998 – 1.03 0.104 21639 209949 all phecode
564.1 Irritable Bowel Syndrome Digestive 1.03 1 – 1.06 0.0314 5508 55117 all phecode
564.8
Abnormal findings on exam of gastrointestinal
Abnormal findings on exam of gastrointestinal tract/ abdominal area
 Digestive 1 0.953 – 1.05 0.931 1645 16457 all phecode
564.9 Personal history of diseases of digestive system Digestive 1 0.987 – 1.02 0.715 15186 151648 all phecode
565 Anal and rectal conditions Digestive 1.01 0.989 – 1.02 0.487 14744 147535 all phecode
565.1 Anal and rectal polyp Digestive 1.02 0.993 – 1.04 0.155 7351 73533 all phecode
567 Peritonitis and retroperitoneal infections Digestive 0.958 0.895 – 1.02 0.207 929 9293 all phecode
568 Other disorders of peritoneum Digestive 1 0.964 – 1.04 0.988 3262 32602 all phecode
568.1
Peritoneal adhesions (postoperative)
Peritoneal adhesions (postoperative) (postinfection)
 Digestive 0.998 0.962 – 1.04 0.912 3101 30987 all phecode
569 Other disorders of intestine Digestive 1.02 0.991 – 1.06 0.158 4192 41922 all phecode
569.1 Toxic gastroenteritis and colitis Digestive 1.14 0.966 – 1.36 0.12 148 1479 all phecode
569.2 Gastrointestinal complications Digestive 0.955 0.87 – 1.05 0.328 486 4868 all phecode
571 Chronic liver disease and cirrhosis Digestive 1.01 0.977 – 1.05 0.442 2957 29628 all phecode
571.5 Other chronic nonalcoholic liver disease Digestive 1.05 0.999 – 1.1 0.0569 1689 16917 all phecode
571.51 Cirrhosis of liver without mention of alcohol Digestive 1.05 0.873 – 1.27 0.581 113 1139 all phecode
571.6 Primary biliary cirrhosis Digestive 0.966 0.848 – 1.1 0.598 257 2568 all phecode
571.8
Liver abscess and sequelae of chronic liver
Liver abscess and sequelae of chronic liver disease
 Digestive 0.999 0.936 – 1.07 0.983 976 9804 all phecode
571.81 Portal hypertension Digestive 1.01 0.924 – 1.1 0.83 528 5285 all phecode
572 Ascites (non malignant) Digestive 0.992 0.941 – 1.05 0.763 1544 15454 all phecode
573 Other disorders of liver Digestive 0.968 0.918 – 1.02 0.225 1496 14982 all phecode
573.2 Liver replaced by transplant Digestive 0.968 0.782 – 1.2 0.766 96 960 all phecode
573.3 Hepatomegaly Digestive 1.01 0.899 – 1.14 0.846 297 2968 all phecode
573.5 Jaundice (not of newborn) Digestive 0.958 0.894 – 1.03 0.223 896 8955 all phecode
573.7 Abnormal results of function study of liver Digestive 1.01 0.979 – 1.05 0.446 3454 34597 all phecode
573.9 Abnormal serum enzyme levels Digestive 1.09 0.944 – 1.25 0.244 209 2089 all phecode
574 Cholelithiasis and cholecystitis Digestive 1.02 0.999 – 1.03 0.0691 15607 156123 all phecode
574.1 Cholelithiasis Digestive 1.01 0.994 – 1.03 0.185 13549 135537 all phecode
574.11 Cholelithiasis with acute cholecystitis Digestive 1.03 0.978 – 1.09 0.264 1506 15072 all phecode
574.12 Cholelithiasis with other cholecystitis Digestive 1 0.973 – 1.03 0.987 5429 54289 all phecode
574.2 Calculus of bile duct Digestive 0.989 0.95 – 1.03 0.591 2620 26191 all phecode
574.3 Cholecystitis without cholelithiasis Digestive 1.06 1.02 – 1.1 0.00493 2748 27523 all phecode
575 Other biliary tract disease Digestive 0.998 0.965 – 1.03 0.894 3867 38724 all phecode
575.1 Cholangitis Digestive 1.01 0.919 – 1.11 0.86 495 4945 all phecode
575.2 Obstruction of bile duct Digestive 0.978 0.908 – 1.05 0.554 774 7756 all phecode
575.6 Cholesterolosis of gallbladder Digestive 1 0.912 – 1.1 0.966 458 4577 all phecode
575.7 Other disorders of gallbladder Digestive 1.04 0.98 – 1.09 0.211 1408 14107 all phecode
575.8 Other disorders of biliary tract Digestive 0.939 0.881 – 1 0.05 1036 10367 all phecode
575.9
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of biliary tract
 Digestive 0.995 0.891 – 1.11 0.931 348 3488 all phecode
577 Diseases of pancreas Digestive 1.02 0.982 – 1.06 0.298 2668 26677 all phecode
577.1 Acute pancreatitis Digestive 1.01 0.969 – 1.06 0.555 1996 19962 all phecode
577.2 Chronic pancreatitis Digestive 1.05 0.964 – 1.15 0.246 515 5149 all phecode
577.3 Cyst and pseudocyst of pancreas Digestive 1.12 1.01 – 1.25 0.0344 365 3650 all phecode
578 Gastrointestinal hemorrhage Digestive 0.996 0.982 – 1.01 0.595 20626 206278 all phecode
578.1 Hematemesis Digestive 0.973 0.929 – 1.02 0.254 1958 19564 all phecode
578.2 Blood in stool Digestive 1 0.962 – 1.04 0.979 2626 26283 all phecode
578.8 Hemorrhage of rectum and anus Digestive 0.994 0.976 – 1.01 0.502 13073 130745 all phecode
578.9 Hemorrhage of gastrointestinal tract Digestive 0.996 0.969 – 1.02 0.801 5275 52787 all phecode
579 Other symptoms involving abdomen and pelvis Digestive 0.999 0.948 – 1.05 0.978 1548 15498 all phecode
579.2 Splenomegaly Digestive 0.975 0.881 – 1.08 0.621 422 4246 all phecode
579.8 Nonspecific abnormal findings in stool contents Digestive 0.95 0.902 – 0.999 0.0471 1654 16540 all phecode
580 Nephritis; nephrosis; renal sclerosis Genitourinary 1.05 0.996 – 1.11 0.0683 1531 15350 all phecode
580.1 Glomerulonephritis Genitourinary 1.02 0.959 – 1.09 0.518 1052 10544 all phecode
580.11 Proliferative glomerulonephritis Genitourinary 1.01 0.802 – 1.28 0.918 74 738 all phecode
580.12 Non-proliferative glomerulonephritis Genitourinary 1.01 0.844 – 1.21 0.913 135 1360 all phecode
580.14 Chronic glomerulonephritis, NOS Genitourinary 1.01 0.947 – 1.09 0.687 876 8769 all phecode
580.2
Nephrotic syndrome without mention of
Nephrotic syndrome without mention of glomerulonephritis
 Genitourinary 1.16 1.06 – 1.28 0.00135 468 4697 all phecode
580.3
Nephritis and nephropathy without mention of
Nephritis and nephropathy without mention of glomerulonephritis
 Genitourinary 1.05 0.919 – 1.2 0.476 246 2460 all phecode
580.32
Nephritis and nephropathy with pathological
Nephritis and nephropathy with pathological lesion
 Genitourinary 1.05 0.926 – 1.2 0.422 253 2529 all phecode
585 Renal failure Genitourinary 1.02 0.991 – 1.04 0.214 6967 69751 all phecode
585.1 Acute renal failure Genitourinary 1.01 0.977 – 1.04 0.628 4527 45305 all phecode
585.2 Renal failure NOS Genitourinary 1 0.947 – 1.06 0.995 1460 14625 all phecode
585.3 Chronic renal failure [CKD] Genitourinary 1.05 1 – 1.09 0.028 2644 26484 all phecode
585.31 Renal dialysis Genitourinary 1.03 0.938 – 1.13 0.558 496 4955 all phecode
586 Other disorders of the kidney and ureters Genitourinary 1 0.967 – 1.04 0.893 3355 33580 all phecode
586.1 Anatomical abnormatilies of kidney and ureters Genitourinary 0.978 0.847 – 1.13 0.765 208 2089 all phecode
586.11 Small kidney Genitourinary 0.985 0.843 – 1.15 0.846 179 1799 all phecode
586.2 Cyst of kidney, acquired Genitourinary 0.991 0.936 – 1.05 0.771 1257 12582 all phecode
586.3 Vascular disorders of kidney/hypertrophy Genitourinary 0.952 0.75 – 1.21 0.688 80 799 all phecode
586.4 Stricture/obstruction of ureter Genitourinary 1.01 0.939 – 1.08 0.867 910 9122 all phecode
587 Kidney replaced by transpant Genitourinary 0.965 0.867 – 1.08 0.521 368 3683 all phecode
588 Disorders resulting from impaired renal function Genitourinary 1.19 0.972 – 1.46 0.0928 99 990 all phecode
589 Abnormal results of function study of kidney Genitourinary 0.945 0.778 – 1.15 0.566 116 1158 all phecode
590 Pyelonephritis Genitourinary 1.02 0.964 – 1.08 0.506 1328 13285 all phecode
591 Urinary tract infection Genitourinary 0.992 0.974 – 1.01 0.392 12400 123937 all phecode
592 Cystitis and urethritis Genitourinary 1.01 0.977 – 1.05 0.458 2966 29661 all phecode
592.1 Cystitis Genitourinary 1.02 0.98 – 1.06 0.364 2904 29035 all phecode
592.11 Acute cystitis Genitourinary 0.847 0.712 – 1.01 0.0624 138 1372 all phecode
592.12 Chronic cystitis Genitourinary 0.983 0.917 – 1.05 0.627 889 8890 all phecode
592.13 Chronic interstitial cystitis Genitourinary 1.01 0.893 – 1.15 0.821 249 2486 all phecode
592.2 Urethritis and urethral syndrome Genitourinary 1.12 0.955 – 1.31 0.165 165 1662 all phecode
593 Hematuria Genitourinary 1.02 1 – 1.04 0.026 16068 160204 all phecode
594 Urinary calculus Genitourinary 1.02 0.997 – 1.05 0.0856 6376 63761 all phecode
594.1 Calculus of kidney Genitourinary 1.01 0.969 – 1.04 0.777 3175 31757 all phecode
594.2 Calculus of lower urinary tract Genitourinary 1.08 1 – 1.16 0.0402 776 7764 all phecode
594.3 Calculus of ureter Genitourinary 1.02 0.975 – 1.06 0.446 2401 24024 all phecode
594.8 Renal colic Genitourinary 1.02 0.971 – 1.06 0.477 2050 20500 all phecode
595 Hydronephrosis Genitourinary 1.03 0.986 – 1.08 0.174 1936 19395 all phecode
596 Other disorders of bladder Genitourinary 1.01 0.992 – 1.03 0.219 9771 97778 all phecode
596.1 Bladder neck obstruction Genitourinary 0.99 0.946 – 1.04 0.68 1969 19690 all phecode
596.5 Functional disorders of bladder Genitourinary 0.947 0.9 – 0.995 0.0322 1658 16572 all phecode
597 Other disorders of urethra and urinary tract Genitourinary 1.03 0.992 – 1.06 0.138 3913 39135 all phecode
597.1 Urethral stricture (not specified as infectious) Genitourinary 1.03 0.996 – 1.07 0.0804 3317 33137 all phecode
597.2 Urinary complications NEC Genitourinary 0.931 0.741 – 1.17 0.534 78 778 all phecode
598 Abnormal findings on examination of urine Genitourinary 1.01 0.976 – 1.05 0.541 3528 35302 all phecode
598.9
Other nonspecific findings on examination of
Other nonspecific findings on examination of urine
 Genitourinary 0.966 0.862 – 1.08 0.559 304 3035 all phecode
599 Other symptoms/disorders or the urinary system Genitourinary 1.01 0.993 – 1.02 0.265 18428 184311 all phecode
599.1 Urinary obstruction Genitourinary 0.892 0.76 – 1.05 0.166 166 1670 all phecode
599.2 Retention of urine Genitourinary 1.02 0.996 – 1.05 0.102 6718 67168 all phecode
599.3 Dysuria Genitourinary 0.98 0.923 – 1.04 0.516 1196 11967 all phecode
599.4 Urinary incontinence Genitourinary 0.993 0.972 – 1.02 0.551 8748 87477 all phecode
599.5 Frequency of urination and polyuria Genitourinary 1.01 0.975 – 1.04 0.659 4018 40144 all phecode
599.6 Oliguria and anuria Genitourinary 1.05 0.858 – 1.28 0.638 105 1059 all phecode
599.8 Other symptoms involving urinary system Genitourinary 1.05 0.811 – 1.37 0.691 62 620 all phecode
599.9 Other abnormality of urination Genitourinary 0.985 0.94 – 1.03 0.534 1913 19151 all phecode
600 Hyperplasia of prostate Genitourinary 1.01 0.992 – 1.03 0.26 11093 87892 all phecode
601 Inflammatory diseases of prostate Genitourinary 1.03 0.981 – 1.07 0.269 2081 20818 all phecode
601.1 Prostatitis Genitourinary 1.02 0.969 – 1.07 0.44 1563 15644 all phecode
601.11 Acute prostatitis Genitourinary 0.993 0.869 – 1.13 0.912 234 2358 all phecode
601.12 Chronic prostatitis Genitourinary 0.994 0.929 – 1.06 0.865 910 9089 all phecode
601.3 Orchitis and epididymitis Genitourinary 0.847 0.651 – 1.1 0.218 59 588 all phecode
601.4 Balanoposthitis Genitourinary 1.06 0.943 – 1.19 0.323 287 2864 all phecode
601.8
Other inflammatory disorders of male genital
Other inflammatory disorders of male genital organs
 Genitourinary 1.07 0.957 – 1.21 0.228 303 3019 all phecode
602 Other disorders of prostate Genitourinary 1.08 1.02 – 1.14 0.00578 1341 13408 all phecode
603 Other disorders of testis Genitourinary 0.99 0.947 – 1.03 0.645 2150 21512 all phecode
603.1 Hydrocele Genitourinary 1.01 0.956 – 1.07 0.715 1339 13402 all phecode
604 Disorders of penis Genitourinary 1.04 1 – 1.08 0.0341 3280 32779 all phecode
604.1 Redundant prepuce and phimosis/BXO Genitourinary 1.03 0.989 – 1.07 0.161 2719 27172 all phecode
605 Erectile dysfunction [ED] Genitourinary 1.08 0.955 – 1.22 0.222 278 2800 all phecode
608 Other disorders of male genital organs Genitourinary 0.944 0.908 – 0.981 0.00344 2822 28236 all phecode
609 Male infertility and abnormal spermatozoa Genitourinary 1.05 0.919 – 1.21 0.457 214 2138 all phecode
609.1 Infertility, male Genitourinary 1.02 0.794 – 1.31 0.881 63 638 all phecode
609.2 Abnormal spermatozoa Genitourinary 1.09 0.944 – 1.27 0.231 169 1698 all phecode
610 Benign mammary dysplasias Genitourinary 0.982 0.942 – 1.02 0.378 2482 24809 all phecode
610.1 Cystic mastopathy Genitourinary 0.961 0.897 – 1.03 0.253 925 9250 all phecode
610.2 Fibroadenosis of breast Genitourinary 1.09 0.972 – 1.22 0.14 306 3057 all phecode
610.3 Fibrosclerosis of breast Genitourinary 0.942 0.836 – 1.06 0.319 302 3018 all phecode
610.4 Benign neoplasm of breast Genitourinary 0.976 0.924 – 1.03 0.388 1388 13865 all phecode
610.8 Other specified benign mammary dysplasias Genitourinary 0.973 0.899 – 1.05 0.49 696 6954 all phecode
611 Abnormal findings on mammogram or breast exam Genitourinary 1 0.949 – 1.05 0.991 1574 15731 all phecode
611.1 Abnormal mammogram Genitourinary 1.03 0.779 – 1.36 0.837 57 569 all phecode
611.3 Lump or mass in breast Genitourinary 0.999 0.947 – 1.05 0.973 1522 15213 all phecode
612
Breast conditions, congenital or relating to
Breast conditions, congenital or relating to hormones
 Genitourinary 0.987 0.921 – 1.06 0.716 887 8871 all phecode
612.2 Hypertrophy of breast (Gynecomastia) Genitourinary 0.975 0.908 – 1.05 0.487 849 8490 all phecode
612.3 Congenital anomalies of breast Genitourinary 1.08 0.859 – 1.37 0.498 72 719 all phecode
613 Other nonmalignant breast conditions Genitourinary 0.972 0.924 – 1.02 0.275 1651 16519 all phecode
613.1 Inflammatory disease of breast Genitourinary 0.992 0.918 – 1.07 0.845 720 7210 all phecode
613.5 Mastodynia Genitourinary 0.931 0.732 – 1.18 0.56 77 768 all phecode
613.7 Other signs and symptoms in breast Genitourinary 0.94 0.869 – 1.02 0.127 702 7013 all phecode
613.8 Other specified disorders of breast Genitourinary 1.05 0.936 – 1.17 0.411 327 3278 all phecode
613.9 Breast disorder NOS Genitourinary 0.975 0.848 – 1.12 0.724 207 2069 all phecode
614 Inflammatory diseases of female pelvic organs Genitourinary 1.03 0.998 – 1.05 0.0727 5711 57118 all phecode
614.1
Pelvic peritoneal adhesions, female
Pelvic peritoneal adhesions, female (postoperative) (postinfection)
 Genitourinary 1.01 0.972 – 1.05 0.554 2538 25363 all phecode
614.3 Pelvic inflammatory disease (PID) Genitourinary 1.04 0.972 – 1.12 0.234 830 8308 all phecode
614.31 Acute inflammatory pelvic disease Genitourinary 1.08 0.83 – 1.41 0.562 61 608 all phecode
614.32 Chronic inflammatory pelvic disease Genitourinary 1.07 0.97 – 1.19 0.172 422 4221 all phecode
614.33 Pelvic inflammatory disease, NOS Genitourinary 1.05 0.939 – 1.17 0.405 351 3510 all phecode
614.4 Inflammatory diseases of uterus, except cervix Genitourinary 1.2 1.06 – 1.36 0.00448 277 2775 all phecode
614.5
Inflammatory disease of cervix, vagina, and
Inflammatory disease of cervix, vagina, and vulva
 Genitourinary 1.04 0.997 – 1.08 0.0719 2601 26023 all phecode
614.51 Cervicitis and endocervicitis Genitourinary 0.991 0.936 – 1.05 0.745 1318 13189 all phecode
614.52 Vaginitis and vulvovaginitis Genitourinary 1.01 0.913 – 1.11 0.885 428 4273 all phecode
614.53 Cyst or abscess of Bartholin's gland Genitourinary 1.03 0.96 – 1.11 0.38 755 7574 all phecode
614.54 Abscess or ulceration of vulva Genitourinary 1.1 0.973 – 1.24 0.13 274 2737 all phecode
615 Endometriosis Genitourinary 1.06 1.03 – 1.09 0.000493 4029 40284 all phecode
617
Disorders secondary to childbirth, surgery
Disorders secondary to childbirth, surgery, trauma
 Genitourinary 1.06 0.941 – 1.19 0.338 304 3037 all phecode
618 Genital prolapse Genitourinary 1.01 0.988 – 1.03 0.451 11689 116878 all phecode
618.1 Prolapse of vaginal walls Genitourinary 0.996 0.973 – 1.02 0.756 7392 73940 all phecode
618.2 Uterine/Uterovaginal prolapse Genitourinary 1.02 0.991 – 1.05 0.184 5393 53918 all phecode
618.5 Prolapse of vaginal vault after hysterectomy Genitourinary 1.05 0.961 – 1.16 0.263 512 5125 all phecode
618.6 Vaginal enterocele, congenital or acquired Genitourinary 0.972 0.898 – 1.05 0.483 680 6794 all phecode
619 Noninflammatory female genital disorders Genitourinary 1.01 0.99 – 1.03 0.298 8726 87297 all phecode
619.1
Noninflammatory disorders of ovary, fallopian
Noninflammatory disorders of ovary, fallopian tube, and broad ligament
 Genitourinary 0.994 0.922 – 1.07 0.878 729 7284 all phecode
619.2 Disorders of uterus, NEC Genitourinary 1.04 1 – 1.08 0.0383 3324 33273 all phecode
619.3 Noninflammatory disorders of cervix Genitourinary 0.984 0.947 – 1.02 0.41 2860 28608 all phecode
619.4 Noninflammatory disorders of vagina Genitourinary 0.961 0.915 – 1.01 0.111 1768 17669 all phecode
619.5 Noninflammatory disorders of vulva and perineum Genitourinary 1.05 0.994 – 1.11 0.0779 1350 13489 all phecode
620 Dysplasia of female genital organs Genitourinary 0.995 0.785 – 1.26 0.965 72 720 all phecode
621 Endometrial hyperplasia Genitourinary 1.08 1.01 – 1.14 0.0187 1129 11294 all phecode
622 Polyp of female genital organs Genitourinary 1.01 0.99 – 1.03 0.31 10480 104803 all phecode
622.1 Polyp of corpus uteri Genitourinary 1.01 0.99 – 1.04 0.251 7857 78601 all phecode
622.2 Mucous polyp of cervix Genitourinary 1.01 0.98 – 1.05 0.414 3442 34387 all phecode
623 Hypertrophy of female genital organs Genitourinary 1.06 1 – 1.13 0.0357 1268 12684 all phecode
624 Symptoms involving female genital tract Genitourinary 1.02 0.949 – 1.1 0.592 797 7961 all phecode
624.1 Dystrophy of female genital tract Genitourinary 1.15 1.01 – 1.31 0.0317 237 2365 all phecode
624.2 Atrophy of female genital tract Genitourinary 0.979 0.887 – 1.08 0.681 440 4398 all phecode
624.9 stress incontinence, female Genitourinary 0.997 0.97 – 1.02 0.814 5865 58634 all phecode
625
Pain and other symptoms associated with female
Pain and other symptoms associated with female genital organs
 Genitourinary 1.01 0.975 – 1.05 0.51 2876 28740 all phecode
625.1 Dyspareunia Genitourinary 0.979 0.922 – 1.04 0.482 1188 11891 all phecode
626
Disorders of menstruation and other abnormal
Disorders of menstruation and other abnormal bleeding from female genital tract
 Genitourinary 1.02 1 – 1.04 0.0224 16168 115018 all phecode
626.1 Irregular menstrual cycle/bleeding Genitourinary 1.02 0.999 – 1.03 0.0648 14110 109918 all phecode
626.11 Absent or infrequent menstruation Genitourinary 0.957 0.789 – 1.16 0.658 109 1099 all phecode
626.12 Excessive or frequent menstruation Genitourinary 1.01 0.99 – 1.03 0.323 9727 91749 all phecode
626.13 Irregular menstrual cycle Genitourinary 1.05 1 – 1.1 0.0398 1985 19829 all phecode
626.14 Irregular menstrual bleeding Genitourinary 1.05 1.01 – 1.08 0.00854 3804 38021 all phecode
626.2 Dysmenorrhea Genitourinary 1.01 0.964 – 1.06 0.62 1778 17767 all phecode
626.4 Premenstrual tension syndromes Genitourinary 1.02 0.868 – 1.21 0.787 159 1587 all phecode
626.8 Infertility, female Genitourinary 1.07 1.01 – 1.13 0.019 1362 13613 all phecode
627 Menopausal and postmenopausal disorders Genitourinary 1.01 0.99 – 1.03 0.311 10392 103948 all phecode
627.1 Postmenopausal bleeding Genitourinary 1.02 0.995 – 1.04 0.125 9042 90439 all phecode
627.2 Symptomatic menopause Genitourinary 0.957 0.823 – 1.11 0.565 183 1826 all phecode
627.3 Postmenopausal atrophic vaginitis Genitourinary 0.978 0.92 – 1.04 0.479 1111 11115 all phecode
627.4 Premenopausal menorrhagia Genitourinary 1.01 0.899 – 1.13 0.87 310 3097 all phecode
628 Ovarian cyst Genitourinary 1.03 0.997 – 1.06 0.0805 4747 47482 all phecode
634 Miscarriage; stillbirth Pregnancy Complications 0.983 0.954 – 1.01 0.244 5218 36422 all phecode
634.1 Missed abortion/Hydatidiform mole Pregnancy Complications 0.967 0.91 – 1.03 0.278 1136 11300 all phecode
634.3 Ectopic pregnancy Pregnancy Complications 0.984 0.877 – 1.1 0.778 331 3305 all phecode
635
Hemorrhage during pregnancy; childbirth and
Hemorrhage during pregnancy; childbirth and postpartum
 Pregnancy Complications 0.95 0.906 – 0.996 0.0319 1974 17372 all phecode
635.2
Antepartum hemorrhage, abruptio placentae, and
Antepartum hemorrhage, abruptio placentae, and placenta previa
 Pregnancy Complications 0.959 0.894 – 1.03 0.252 866 8614 all phecode
635.3 Placenta previa and abruptio placenta Pregnancy Complications 0.934 0.882 – 0.99 0.022 1270 12306 all phecode
636
Early or threatened labor; hemorrhage in early
Early or threatened labor; hemorrhage in early pregnancy
 Pregnancy Complications 1.01 0.964 – 1.05 0.78 2347 19972 all phecode
636.2 Early onset of delivery Pregnancy Complications 1.06 0.973 – 1.15 0.189 617 6144 all phecode
636.3 Hemorrhage in early pregnancy Pregnancy Complications 0.996 0.936 – 1.06 0.897 1082 10766 all phecode
638 Other high-risk pregnancy Pregnancy Complications 0.981 0.768 – 1.25 0.878 70 700 all phecode
642
Hypertension complicating pregnancy
Hypertension complicating pregnancy, childbirth, and the puerperium
 Pregnancy Complications 1.05 0.986 – 1.11 0.134 1110 11074 all phecode
642.1 Preeclampsia and eclampsia Pregnancy Complications 1.21 1.08 – 1.36 0.00143 307 3058 all phecode
643 Excessive vomiting in pregnancy Pregnancy Complications 1.02 0.883 – 1.17 0.828 215 2149 all phecode
643.1 Hyperemesis gravidarum Pregnancy Complications 1.03 0.872 – 1.21 0.734 153 1525 all phecode
645 Late pregnancy and failed induction Pregnancy Complications 0.947 0.893 – 1 0.0667 1250 12450 all phecode
646 Other complications of pregnancy NEC Pregnancy Complications 1.03 0.981 – 1.07 0.267 2228 20847 all phecode
647
Infectious and parasitic complications
Infectious and parasitic complications affecting pregnancy
 Pregnancy Complications 1.31 1.03 – 1.68 0.0296 68 679 all phecode
647.1
Infections of genitourinary tract during
Infections of genitourinary tract during pregnancy
 Pregnancy Complications 1.03 0.907 – 1.16 0.684 275 2748 all phecode
649
Other conditions or status of the mother
Other conditions or status of the mother complicating pregnancy, childbirth, or the puerperium
 Pregnancy Complications 0.999 0.83 – 1.2 0.994 113 1129 all phecode
649.1
Diabetes or abnormal glucose tolerance
Diabetes or abnormal glucose tolerance complicating pregnancy
 Pregnancy Complications 1.25 1.08 – 1.45 0.00295 193 1922 all phecode
650 Normal delivery Pregnancy Complications 1.01 0.965 – 1.06 0.652 1922 18973 all phecode
651 Multiple gestation Pregnancy Complications 1.1 0.985 – 1.23 0.0911 346 3454 all phecode
652
Malposition and malpresentation of fetus or
Malposition and malpresentation of fetus or obstruction
 Pregnancy Complications 0.987 0.939 – 1.04 0.601 1716 16521 all phecode
653
Problems associated with amniotic cavity and
Problems associated with amniotic cavity and membranes
 Pregnancy Complications 0.948 0.897 – 1 0.0572 1401 13649 all phecode
654
Other and unspecified complications of birth
Other and unspecified complications of birth; puerperium affecting management of mother
 Pregnancy Complications 0.915 0.727 – 1.15 0.449 74 739 all phecode
655
Known or suspected fetal abnormality affecting
Known or suspected fetal abnormality affecting management of mother
 Pregnancy Complications 0.982 0.951 – 1.01 0.28 4306 29454 all phecode
656 Other perinatal conditions of fetus or newborn Pregnancy Complications 0.893 0.735 – 1.08 0.251 109 1080 all phecode
661 Fetal distress and abnormal forces of labor Pregnancy Complications 0.984 0.942 – 1.03 0.48 2265 18397 all phecode
663
Umbilical cord complications during labor and
Umbilical cord complications during labor and delivery
 Pregnancy Complications 1.01 0.927 – 1.11 0.77 532 5316 all phecode
665 Obstetrical/birth trauma Pregnancy Complications 0.983 0.955 – 1.01 0.268 5313 29472 all phecode
669 Complications of labor and delivery NEC Pregnancy Complications 0.976 0.937 – 1.02 0.258 2552 21174 all phecode
671
Venous/cerebrovascular complications embolism
Venous/cerebrovascular complications embolism in pregnancy and the puerperium
 Pregnancy Complications 0.953 0.809 – 1.12 0.566 164 1628 all phecode
674 Other complications of the puerperium NEC Pregnancy Complications 1.08 0.948 – 1.23 0.252 262 2605 all phecode
676
Other disorders of the breast associated with
Other disorders of the breast associated with childbirth and disorders of lactation
 Pregnancy Complications 1.13 0.863 – 1.47 0.381 63 624 all phecode
679 Complications of in utero procedures Dermatologic 0.795 0.595 – 1.06 0.12 53 530 all phecode
681 Superficial cellulitis and abscess Dermatologic 0.995 0.972 – 1.02 0.713 7200 72225 all phecode
681.1 Cellulitis and abscess of fingers/toes Dermatologic 0.999 0.916 – 1.09 0.976 563 5647 all phecode
681.2 Cellulitis and abscess of face/neck Dermatologic 0.985 0.901 – 1.08 0.741 520 5208 all phecode
681.3 Cellulitis and abscess of arm/hand Dermatologic 0.985 0.958 – 1.01 0.284 5481 55014 all phecode
681.5 Cellulitis and abscess of leg, except foot Dermatologic 0.988 0.961 – 1.02 0.391 5487 55074 all phecode
681.6 Cellulitis and abscess of foot, toe Dermatologic 0.986 0.959 – 1.01 0.324 5444 54643 all phecode
681.7 Cellulitis and abscess of trunk Dermatologic 1.02 0.937 – 1.11 0.675 597 5987 all phecode
686
Other local infections of skin and subcutaneous
Other local infections of skin and subcutaneous tissue
 Dermatologic 1.02 0.964 – 1.08 0.5 1337 13427 all phecode
686.1 Carbuncle and furuncle Dermatologic 1.03 0.983 – 1.07 0.247 2284 22925 all phecode
686.3 Pilonidal cyst Dermatologic 1.02 0.939 – 1.11 0.604 583 5837 all phecode
686.4 Pyogenic granuloma Dermatologic 1.07 0.957 – 1.19 0.246 362 3615 all phecode
687 Symptoms affecting skin Dermatologic 1.01 0.929 – 1.11 0.742 548 5508 all phecode
687.1 Rash and other nonspecific skin eruption Dermatologic 0.998 0.955 – 1.04 0.941 2146 21470 all phecode
687.2 Localized superficial swelling, mass, or lump Dermatologic 1.03 0.91 – 1.17 0.629 283 2839 all phecode
687.3 Changes in skin texture Dermatologic 0.946 0.781 – 1.15 0.57 106 1070 all phecode
687.4 Disturbance of skin sensation Dermatologic 0.992 0.955 – 1.03 0.675 2884 28859 all phecode
689 Disorder of skin and subcutaneous tissue NOS Dermatologic 1.01 0.981 – 1.04 0.554 5747 57521 all phecode
690 Erythematosquamous dermatosis Dermatologic 0.996 0.786 – 1.26 0.974 71 710 all phecode
690.1 Seborrheic dermatitis Dermatologic 0.92 0.694 – 1.22 0.56 53 530 all phecode
691 Congenital anomalies of skin Dermatologic 0.909 0.753 – 1.1 0.318 120 1199 all phecode
694 Dyschromia and Vitiligo Dermatologic 1.01 0.95 – 1.08 0.673 986 9854 all phecode
694.1 Vitiligo Dermatologic 1.22 0.933 – 1.58 0.148 60 599 all phecode
694.2 Other dyschromia Dermatologic 1.02 0.947 – 1.1 0.597 782 7821 all phecode
694.3 Vascular disorders of skin Dermatologic 0.886 0.731 – 1.07 0.217 117 1170 all phecode
695 Erythematous conditions Dermatologic 0.983 0.943 – 1.03 0.437 2379 23813 all phecode
695.1 Toxic erythema Dermatologic 1.09 0.895 – 1.32 0.395 109 1090 all phecode
695.2 Bullous dermatoses Dermatologic 0.909 0.761 – 1.09 0.296 137 1365 all phecode
695.21 Dermatitis herpetiformis Dermatologic 0.864 0.655 – 1.14 0.303 57 569 all phecode
695.22 Pemphigus and pemphigoid Dermatologic 0.864 0.677 – 1.1 0.243 73 727 all phecode
695.3 Rosacea Dermatologic 1.14 1.01 – 1.28 0.0308 309 3097 all phecode
695.4 Lupus (localized and systemic) Dermatologic 0.891 0.805 – 0.987 0.0272 411 4114 all phecode
695.41 Cutaneous lupus erythematosus Dermatologic 0.935 0.781 – 1.12 0.465 130 1295 all phecode
695.42 Systemic lupus erythematosus Dermatologic 0.872 0.78 – 0.975 0.0166 340 3407 all phecode
695.7 Prurigo and Lichen Dermatologic 0.992 0.921 – 1.07 0.82 775 7760 all phecode
695.8 Other specified erythematous conditions Dermatologic 1.07 0.933 – 1.22 0.343 236 2359 all phecode
695.81 Erythema nodosum Dermatologic 0.935 0.737 – 1.19 0.58 76 760 all phecode
695.9 Unspecified erythematous condition Dermatologic 0.903 0.82 – 0.993 0.0361 467 4672 all phecode
696 Psoriasis and related disorders Dermatologic 1.02 0.978 – 1.07 0.336 2252 22509 all phecode
696.4 Psoriasis Dermatologic 1.03 0.982 – 1.07 0.242 2198 21969 all phecode
696.41 Psoriasis vulgaris Dermatologic 1.04 0.993 – 1.1 0.0956 1680 16796 all phecode
696.42 Psoriatic arthropathy Dermatologic 0.987 0.913 – 1.07 0.743 706 7052 all phecode
697 Sarcoidosis Dermatologic 1 0.918 – 1.1 0.926 539 5373 all phecode
698 Pruritus and related conditions Dermatologic 1.02 0.949 – 1.1 0.577 782 7814 all phecode
700 Corns and callosities Dermatologic 0.895 0.792 – 1.01 0.0767 291 2904 all phecode
701
Other hypertrophic and atrophic conditions of
Other hypertrophic and atrophic conditions of skin
 Dermatologic 0.975 0.946 – 1 0.101 4663 46650 all phecode
701.1 Keratoderma, acquired Dermatologic 0.783 0.629 – 0.975 0.029 87 870 all phecode
701.2 Scar conditions and fibrosis of skin Dermatologic 0.953 0.913 – 0.995 0.0271 2348 23478 all phecode
701.3 Circumscribed scleroderma Dermatologic 1.21 0.934 – 1.57 0.148 61 610 all phecode
701.4 Keloid scar Dermatologic 1.03 0.891 – 1.18 0.72 216 2159 all phecode
701.5 Abnormal granulation tissue Dermatologic 0.947 0.861 – 1.04 0.263 455 4568 all phecode
701.6 Acquired acanthosis nigricans Dermatologic 1.08 0.886 – 1.32 0.439 102 1019 all phecode
702
Degenerative skin conditions and other
Degenerative skin conditions and other dermatoses
 Dermatologic 0.998 0.97 – 1.03 0.875 5459 54587 all phecode
702.1 Actinic keratosis Dermatologic 0.994 0.955 – 1.04 0.771 2585 25842 all phecode
702.2 Seborrheic keratosis Dermatologic 1 0.967 – 1.04 0.877 3078 30772 all phecode
703 Diseases of nail, NOS Dermatologic 1.03 0.925 – 1.14 0.6 354 3539 all phecode
703.1 Ingrowing nail Dermatologic 0.992 0.928 – 1.06 0.804 966 9660 all phecode
704 Diseases of hair and hair follicles Dermatologic 1.01 0.978 – 1.04 0.652 5267 52727 all phecode
704.1 Alopecia Dermatologic 1.03 0.867 – 1.24 0.707 125 1269 all phecode
704.8
Other specified diseases of hair and hair
Other specified diseases of hair and hair follicles
 Dermatologic 0.945 0.748 – 1.19 0.632 76 759 all phecode
705 Disorders of sweat glands Dermatologic 0.935 0.818 – 1.07 0.32 228 2287 all phecode
705.3 Hidradenitis Dermatologic 0.945 0.818 – 1.09 0.447 186 1868 all phecode
705.8 Hyperhidrosis Dermatologic 1.01 0.932 – 1.1 0.75 591 5919 all phecode
706 Diseases of sebaceous glands Dermatologic 1 0.981 – 1.03 0.785 8317 83195 all phecode
706.1 Acne Dermatologic 1.21 0.968 – 1.5 0.095 78 779 all phecode
706.2 Sebaceous cyst Dermatologic 1 0.981 – 1.02 0.832 8787 87882 all phecode
707 Chronic ulcer of skin Dermatologic 1.02 0.976 – 1.07 0.349 1953 19654 all phecode
707.1 Decubitus ulcer Dermatologic 0.987 0.922 – 1.06 0.701 909 9097 all phecode
709 Diffuse diseases of connective tissue Dermatologic 1.05 1.01 – 1.08 0.0106 3432 34317 all phecode
709.2 Sicca syndrome Dermatologic 1.02 0.928 – 1.11 0.714 508 5073 all phecode
709.3 Systemic sclerosis Dermatologic 1.08 0.924 – 1.26 0.337 176 1753 all phecode
709.6
Other specified diffuse diseases of connective
Other specified diffuse diseases of connective tissue
 Dermatologic 1.1 0.858 – 1.4 0.465 65 649 all phecode
709.7 Unspecified diffuse connective tissue disease Dermatologic 1.05 1.01 – 1.09 0.015 2714 27144 all phecode
710
Osteomyelitis, periostitis, and other
Osteomyelitis, periostitis, and other infections involving bone
 Musculoskeletal 1.08 0.997 – 1.17 0.0599 602 6034 all phecode
710.1 Osteomyelitis Musculoskeletal 1.1 1.01 – 1.2 0.0269 556 5574 all phecode
710.12 Chronic osteomyelitis Musculoskeletal 0.949 0.82 – 1.1 0.481 194 1947 all phecode
710.19 Unspecified osteomyelitis Musculoskeletal 1.14 1.03 – 1.25 0.0127 398 3997 all phecode
711 Arthropathy associated with infections Musculoskeletal 0.947 0.858 – 1.05 0.281 421 4225 all phecode
711.1 Pyogenic arthritis Musculoskeletal 0.962 0.86 – 1.07 0.49 328 3296 all phecode
712 Infective connective tissue disorders Musculoskeletal 0.99 0.798 – 1.23 0.929 81 810 all phecode
713
Arthropathy associated with other disorders
Arthropathy associated with other disorders classified elsewhere
 Musculoskeletal 1.2 1.02 – 1.42 0.0285 148 1499 all phecode
713.5
Arthropathy associated with neurological
Arthropathy associated with neurological disorders
 Musculoskeletal 1.59 1.24 – 2.05 0.000307 65 669 all phecode
714
Rheumatoid arthritis and other inflammatory
Rheumatoid arthritis and other inflammatory polyarthropathies
 Musculoskeletal 1.08 1.05 – 1.12 7.36e-08 4832 48320 all phecode
714.1 Rheumatoid arthritis Musculoskeletal 1.1 1.06 – 1.13 6.97e-09 4372 43714 all phecode
715 Other inflammatory spondylopathies Musculoskeletal 1.02 0.969 – 1.07 0.468 1659 16588 all phecode
715.1 Sacroiliitis NEC Musculoskeletal 1.03 0.849 – 1.24 0.782 113 1129 all phecode
715.2 Ankylosing spondylitis Musculoskeletal 1.12 1.03 – 1.22 0.00722 618 6177 all phecode
716 Other arthropathies Musculoskeletal 1 0.993 – 1.02 0.458 37478 265375 all phecode
716.1 Unspecified polyarthropathy or polyarthritis Musculoskeletal 0.998 0.963 – 1.03 0.89 3505 35090 all phecode
716.2 Unspecified monoarthritis Musculoskeletal 0.991 0.975 – 1.01 0.282 15522 155339 all phecode
716.9 Arthropathy NOS Musculoskeletal 1 0.994 – 1.02 0.386 35944 262308 all phecode
717 Polymyalgia Rheumatica Musculoskeletal 1.12 1.05 – 1.19 0.000272 1145 11480 all phecode
720 Spinal stenosis Musculoskeletal 1.01 0.977 – 1.04 0.544 3705 37091 all phecode
721 Spondylosis and allied disorders Musculoskeletal 1.02 0.992 – 1.04 0.202 7832 78318 all phecode
721.1 Spondylosis without myelopathy Musculoskeletal 0.998 0.97 – 1.03 0.907 5045 50451 all phecode
721.2 Spondylosis with myelopathy Musculoskeletal 1.12 0.964 – 1.3 0.14 189 1899 all phecode
721.8 Other allied disorders of spine Musculoskeletal 1.09 0.977 – 1.22 0.12 352 3519 all phecode
722 Intervertebral disc disorders Musculoskeletal 1.01 0.991 – 1.03 0.252 8978 89848 all phecode
722.1 Displacement of intervertebral disc Musculoskeletal 1.09 0.999 – 1.2 0.0532 512 5116 all phecode
722.6 Degeneration of intervertebral disc Musculoskeletal 1.03 0.988 – 1.07 0.183 2831 28328 all phecode
722.8 Postlaminectomy syndrome Musculoskeletal 1.17 0.923 – 1.49 0.193 67 669 all phecode
722.9 Other and unspecified disc disorder Musculoskeletal 1.01 0.981 – 1.04 0.453 4407 44127 all phecode
723 Other disorders of cervical region Musculoskeletal 1.01 0.924 – 1.1 0.844 517 5173 all phecode
723.1 Torticollis Musculoskeletal 1.14 0.939 – 1.39 0.183 107 1068 all phecode
724 Other and unspecified disorders of back Musculoskeletal 1.03 0.986 – 1.08 0.177 2052 20514 all phecode
724.1 Disorders of sacrum Musculoskeletal 0.968 0.872 – 1.07 0.539 403 4024 all phecode
724.2 Disorders of coccyx Musculoskeletal 0.972 0.876 – 1.08 0.598 406 4054 all phecode
724.8 Other symptoms referable to back Musculoskeletal 1.27 0.98 – 1.66 0.0701 63 630 all phecode
724.9 Other unspecified back disorders Musculoskeletal 1.04 0.988 – 1.09 0.135 1614 16139 all phecode
726 Peripheral enthesopathies and allied syndromes Musculoskeletal 1.01 0.993 – 1.03 0.249 14663 146691 all phecode
726.1 Enthesopathy Musculoskeletal 1 0.984 – 1.03 0.642 9589 95900 all phecode
726.2 Synoviopathy Musculoskeletal 1.07 0.958 – 1.19 0.231 334 3336 all phecode
726.3 Bursitis Musculoskeletal 1.04 0.97 – 1.12 0.271 854 8573 all phecode
727 Other disorders of synovium, tendon, and bursa Musculoskeletal 1.03 1.01 – 1.06 0.0134 7331 73332 all phecode
727.1 Synovitis and tenosynovitis Musculoskeletal 1.03 0.986 – 1.07 0.215 2737 27406 all phecode
727.2 Bursitis disorders Musculoskeletal 0.929 0.756 – 1.14 0.478 103 1029 all phecode
727.4 Ganglion and cyst of synovium, tendon, and bursa Musculoskeletal 1.04 0.999 – 1.08 0.0559 3109 31085 all phecode
727.5 Rupture of synovium Musculoskeletal 1.01 0.924 – 1.09 0.898 586 5854 all phecode
727.6 Rupture of tendon, nontraumatic Musculoskeletal 1.04 0.93 – 1.16 0.508 353 3527 all phecode
727.7 Contracture of tendon (sheath) Musculoskeletal 0.933 0.788 – 1.11 0.423 143 1429 all phecode
728 Disorders of muscle, ligament, and fascia Musculoskeletal 1.07 1.03 – 1.1 0.000192 3677 36788 all phecode
728.2 Laxity of ligament or hypermobility syndrome Musculoskeletal 0.972 0.878 – 1.08 0.583 412 4115 all phecode
728.7 Fasciitis Musculoskeletal 1.06 1.03 – 1.1 0.000505 3803 38045 all phecode
728.71
Contracture of palmar fascia [Dupuytren's
Contracture of palmar fascia [Dupuytren's disease]
 Musculoskeletal 1.07 1.04 – 1.11 5.32e-05 3477 34788 all phecode
729 Other disorders of soft tissues Musculoskeletal 1 0.975 – 1.03 0.898 6014 60309 all phecode
729.1 Rheumatism, unspecified and fibrositis Musculoskeletal 1.02 0.954 – 1.09 0.599 1005 10063 all phecode
729.3 Panniculitis Musculoskeletal 0.793 0.643 – 0.979 0.0307 101 1009 all phecode
731
Osteitis deformans and osteopathies associated
Osteitis deformans and osteopathies associated with other disorders classified elsewhere
 Musculoskeletal 1.13 0.998 – 1.28 0.0541 276 2758 all phecode
731.1 Osteitis deformans [Paget's disease of bone] Musculoskeletal 1.1 0.971 – 1.25 0.131 261 2609 all phecode
732 Osteochondropathies Musculoskeletal 0.908 0.822 – 1 0.0557 467 4679 all phecode
732.1 Juvenile osteochondrosis Musculoskeletal 0.916 0.79 – 1.06 0.247 207 2068 all phecode
732.7 Osteochondritis dissecans Musculoskeletal 0.845 0.642 – 1.11 0.231 57 570 all phecode
733 Other disorders of bone and cartilage Musculoskeletal 0.965 0.919 – 1.01 0.151 1777 17814 all phecode
733.2 Cyst of bone Musculoskeletal 0.897 0.8 – 1.01 0.0633 311 3115 all phecode
733.4 Aseptic necrosis of bone Musculoskeletal 1.03 0.941 – 1.12 0.55 540 5393 all phecode
733.6 Costochondritis Musculoskeletal 0.857 0.711 – 1.03 0.105 128 1276 all phecode
733.8 Malunion and nonunion of fracture Musculoskeletal 1.05 0.991 – 1.11 0.0949 1231 12313 all phecode
733.9 Chondromalacia Musculoskeletal 1.02 0.846 – 1.23 0.844 121 1206 all phecode
735 Acquired foot deformities Musculoskeletal 1 0.983 – 1.03 0.709 9603 96090 all phecode
735.1 Flat foot Musculoskeletal 0.938 0.809 – 1.09 0.396 189 1910 all phecode
735.2 Acquired toe deformities Musculoskeletal 1 0.976 – 1.03 0.782 5070 50712 all phecode
735.21 Hammer toe (acquired) Musculoskeletal 0.985 0.94 – 1.03 0.533 1929 19324 all phecode
735.23 Hallux rigidus Musculoskeletal 1.04 0.985 – 1.09 0.16 1555 15527 all phecode
735.3 Hallux valgus (Bunion) Musculoskeletal 0.999 0.975 – 1.03 0.967 6643 66463 all phecode
736 Other acquired deformities of limbs Musculoskeletal 1.03 0.976 – 1.08 0.303 1627 16282 all phecode
736.2 Acquired deformities of finger Musculoskeletal 1.03 0.903 – 1.17 0.694 248 2476 all phecode
737 Curvature of spine Musculoskeletal 0.995 0.936 – 1.06 0.869 1128 11300 all phecode
737.3 Kyphoscoliosis and scoliosis Musculoskeletal 0.994 0.933 – 1.06 0.843 1061 10632 all phecode
738 Other acquired musculoskeletal deformity Musculoskeletal 0.999 0.954 – 1.05 0.98 1904 19058 all phecode
738.4 Acquired spondylolisthesis Musculoskeletal 1.01 0.957 – 1.06 0.733 1513 15147 all phecode
739 Contracture of joint Musculoskeletal 1.04 0.944 – 1.14 0.462 488 4884 all phecode
740 Osteoarthrosis Musculoskeletal 1.01 0.995 – 1.02 0.252 27707 231603 all phecode
740.1 Osteoarthritis; localized Musculoskeletal 1.01 0.99 – 1.02 0.448 17412 169419 all phecode
740.11 Osteoarthrosis, localized, primary Musculoskeletal 1.01 0.986 – 1.03 0.504 8974 89750 all phecode
740.12 Osteoarthrosis, localized, secondary Musculoskeletal 1.06 0.951 – 1.18 0.289 348 3474 all phecode
740.2 Osteoarthrosis, generalized Musculoskeletal 1.01 0.926 – 1.1 0.864 598 5969 all phecode
740.9 Osteoarthrosis NOS Musculoskeletal 1.01 0.988 – 1.03 0.516 12270 122792 all phecode
741 Symptoms and disorders of the joints Musculoskeletal 1.02 0.99 – 1.06 0.16 3563 35648 all phecode
741.1 Ankylosis of joint Musculoskeletal 1.14 0.935 – 1.39 0.196 102 1019 all phecode
741.2 Stiffness of joint Musculoskeletal 1 0.926 – 1.09 0.91 614 6146 all phecode
741.3 Difficulty in walking Musculoskeletal 0.944 0.8 – 1.11 0.496 154 1540 all phecode
741.4 Joint effusions Musculoskeletal 1.09 1.03 – 1.14 0.00282 1418 14197 all phecode
741.5 Hemarthrosis Musculoskeletal 1.14 0.939 – 1.37 0.189 110 1100 all phecode
741.6 Villonodular synovitis Musculoskeletal 0.964 0.734 – 1.26 0.79 54 535 all phecode
742 Derangement of joint, non-traumatic Musculoskeletal 1 0.965 – 1.04 0.872 2843 28441 all phecode
742.1 Loose body in joint Musculoskeletal 0.984 0.882 – 1.1 0.766 333 3337 all phecode
742.2
Pathological, developmental or recurrent
Pathological, developmental or recurrent dislocation
 Musculoskeletal 1.04 0.853 – 1.28 0.679 95 960 all phecode
742.8 Articular cartilage disorder Musculoskeletal 1.06 0.965 – 1.16 0.23 500 4996 all phecode
742.9 Other derangement of joint Musculoskeletal 0.991 0.947 – 1.04 0.71 1993 19926 all phecode
743
Osteoporosis, osteopenia and pathological
Osteoporosis, osteopenia and pathological fracture
 Musculoskeletal 0.998 0.975 – 1.02 0.873 7563 75729 all phecode
743.1 Osteoporosis Musculoskeletal 0.992 0.966 – 1.02 0.521 6400 64107 all phecode
743.11 Osteoporosis NOS Musculoskeletal 0.992 0.965 – 1.02 0.574 5549 55604 all phecode
743.13 Other specified osteoporosis Musculoskeletal 1.06 0.973 – 1.16 0.179 529 5283 all phecode
743.2 Pathologic fracture Musculoskeletal 0.986 0.902 – 1.08 0.76 516 5179 all phecode
743.9
Osteopenia or other disorder of bone and
Osteopenia or other disorder of bone and cartilage
 Musculoskeletal 1.06 0.988 – 1.14 0.105 815 8144 all phecode
745 Pain in joint Musculoskeletal 0.985 0.963 – 1.01 0.207 7975 79789 all phecode
747 Cardiac and circulatory congenital anomalies Congenital Anomalies 0.996 0.957 – 1.04 0.823 2802 28058 all phecode
747.1 Cardiac congenital anomalies Congenital Anomalies 0.993 0.954 – 1.03 0.747 2628 26323 all phecode
747.11 Cardiac shunt/ heart septal defect Congenital Anomalies 1.04 0.957 – 1.14 0.339 584 5838 all phecode
747.12 Valvular heart disease/ heart chambers Congenital Anomalies 0.968 0.849 – 1.1 0.631 235 2358 all phecode
747.13 Congenital anomalies of great vessels Congenital Anomalies 1 0.956 – 1.05 0.881 1816 18200 all phecode
747.2
Congenital anomalies of peripheral vascular
Congenital anomalies of peripheral vascular system
 Congenital Anomalies 0.968 0.826 – 1.13 0.684 167 1680 all phecode
748 Anomalies of respiratory system, congenital Congenital Anomalies 0.922 0.699 – 1.22 0.565 51 510 all phecode
749 Congenital anomalies of face and neck Congenital Anomalies 0.984 0.875 – 1.11 0.785 303 3029 all phecode
750 Digestive congenital anomalies Congenital Anomalies 0.912 0.843 – 0.987 0.0218 686 6870 all phecode
750.1 Upper gastrointestinal congenital anomalies Congenital Anomalies 0.879 0.784 – 0.986 0.0277 327 3263 all phecode
750.13 Congenital anomalies of mouth/tongue Congenital Anomalies 0.894 0.77 – 1.04 0.137 191 1909 all phecode
750.2 Lower gastrointestinal congenital anomalies Congenital Anomalies 0.948 0.85 – 1.06 0.333 356 3574 all phecode
750.21 Congenital anomalies of intestine Congenital Anomalies 0.933 0.814 – 1.07 0.316 225 2256 all phecode
750.22
Congenital anomaly of gallbladder, bile ducts
Congenital anomaly of gallbladder, bile ducts, liver, pancreas
 Congenital Anomalies 1 0.832 – 1.21 0.961 117 1179 all phecode
751 Genitourinary congenital anomalies Congenital Anomalies 0.964 0.915 – 1.02 0.176 1527 15286 all phecode
751.1 Congenital anomalies of genital organs Congenital Anomalies 0.992 0.918 – 1.07 0.837 694 6932 all phecode
751.11 Congenital anomalies of female genital organs Congenital Anomalies 1.06 0.962 – 1.17 0.243 455 4546 all phecode
751.12 Congenital anomalies of male genital organs Congenital Anomalies 0.904 0.785 – 1.04 0.159 222 2217 all phecode
751.2 Congenital anomalies of urinary system Congenital Anomalies 0.939 0.875 – 1.01 0.0829 836 8385 all phecode
751.21 Cystic kidney disease Congenital Anomalies 0.907 0.82 – 1 0.0563 424 4246 all phecode
751.22 Other specified congenital anomalies of kidney Congenital Anomalies 0.995 0.889 – 1.11 0.933 333 3346 all phecode
752 Nervous system congenital anomalies Congenital Anomalies 0.902 0.804 – 1.01 0.0778 328 3307 all phecode
752.1 Neural tube defects Congenital Anomalies 0.876 0.769 – 0.997 0.0448 253 2557 all phecode
752.11 Spina bifida Congenital Anomalies 0.833 0.722 – 0.962 0.0126 208 2108 all phecode
752.2
Other specified congenital anomalies of nervous
Other specified congenital anomalies of nervous system
 Congenital Anomalies 0.964 0.758 – 1.23 0.765 78 780 all phecode
753 Congenital anomalies of the eye Congenital Anomalies 1 0.835 – 1.21 0.971 127 1270 all phecode
753.1 Congenital cataract and lens anomalies Congenital Anomalies 0.869 0.678 – 1.11 0.265 76 760 all phecode
754 Congenital musculoskeletal deformities of spine Congenital Anomalies 1.06 0.873 – 1.29 0.541 109 1099 all phecode
755 Congenital anomalies of limbs Congenital Anomalies 0.996 0.901 – 1.1 0.931 425 4276 all phecode
755.1 Congenital deformities of feet Congenital Anomalies 1.04 0.902 – 1.2 0.597 208 2086 all phecode
755.6
Other congenital anomalies of lower limb
Other congenital anomalies of lower limb, including pelvic girdle
 Congenital Anomalies 0.955 0.811 – 1.13 0.583 160 1620 all phecode
755.61 Congenital hip dysplasia and deformity Congenital Anomalies 0.943 0.77 – 1.15 0.569 106 1070 all phecode
756 Other congenital musculoskeletal anomalies Congenital Anomalies 1.01 0.93 – 1.1 0.785 587 5872 all phecode
756.3
Congenital anomalies of muscle, tendon, fascia
Congenital anomalies of muscle, tendon, fascia, and connective tissue
 Congenital Anomalies 1.09 0.875 – 1.36 0.438 81 810 all phecode
756.5 Congenital osteodystrophies Congenital Anomalies 1.02 0.926 – 1.13 0.662 435 4356 all phecode
758 Chromosomal anomalies and genetic disorders Congenital Anomalies 0.925 0.786 – 1.09 0.352 148 1708 all phecode
758.1 Chromosomal anomalies Congenital Anomalies 1.04 0.808 – 1.34 0.763 60 830 all phecode
759 Other and unspecified congenital anomalies Congenital Anomalies 1.11 0.962 – 1.27 0.156 216 2159 all phecode
759.1 Anomalies of endocrine glands, congenital Congenital Anomalies 1.02 0.834 – 1.25 0.844 96 959 all phecode
760 Back pain Symptoms 0.994 0.975 – 1.01 0.563 11126 111353 all phecode
761 Cervicalgia Symptoms 1.02 0.976 – 1.07 0.334 1791 17901 all phecode
764 Sciatica Symptoms 0.994 0.952 – 1.04 0.762 2372 23732 all phecode
766 Neuralgia, neuritis, and radiculitis NOS Symptoms 0.952 0.896 – 1.01 0.112 1172 11738 all phecode
770 Myalgia and myositis unspecified Symptoms 1.06 0.974 – 1.14 0.189 631 6311 all phecode
771 Musculoskeletal symptoms referable to limbs Symptoms 0.987 0.92 – 1.06 0.706 870 8687 all phecode
771.1 Swelling of limb Symptoms 0.991 0.962 – 1.02 0.58 4617 46330 all phecode
772 Symptoms of the muscles Symptoms 1.01 0.933 – 1.1 0.796 659 6581 all phecode
773 Pain in limb Symptoms 0.996 0.971 – 1.02 0.79 6209 62203 all phecode
780 Hypothermia/Chills Symptoms 0.954 0.818 – 1.11 0.553 171 1719 all phecode
781
Symptoms involving nervous and musculoskeletal
Symptoms involving nervous and musculoskeletal systems
 Symptoms 0.986 0.94 – 1.03 0.555 1870 18715 all phecode
782.3 Edema Symptoms 0.983 0.935 – 1.03 0.499 1642 16450 all phecode
782.6 Pallor and flushing Symptoms 1.09 0.932 – 1.27 0.285 175 1748 all phecode
783 Fever of unknown origin Symptoms 1.02 0.989 – 1.06 0.191 3911 39105 all phecode
785 Abdominal pain Symptoms 1.01 0.997 – 1.02 0.137 40080 301686 all phecode
788 Syncope and collapse Symptoms 1.01 0.986 – 1.03 0.492 9069 90813 all phecode
789 Nausea and vomiting Symptoms 1.01 0.988 – 1.03 0.502 11577 115807 all phecode
790 Nonspecific findings on examination of blood Symptoms 0.904 0.766 – 1.07 0.232 150 1500 all phecode
790.1 Elevated sedimentation rate Symptoms 1.05 0.847 – 1.29 0.68 84 840 all phecode
790.6 Other abnormal blood chemistry Symptoms 1.01 0.981 – 1.03 0.597 6357 63635 all phecode
791 Gangrene Symptoms 1.05 0.964 – 1.15 0.252 549 5501 all phecode
792
Abnormal Papanicolaou smear of cervix and
Abnormal Papanicolaou smear of cervix and cervical HPV
 Symptoms 1 0.808 – 1.24 0.999 98 966 all phecode
793
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of musculoskeletal system
 Symptoms 1.02 0.853 – 1.21 0.854 134 1340 all phecode
793.2
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of other intrathoracic organs (echocardiogram, etc)
 Symptoms 0.974 0.893 – 1.06 0.558 565 5647 all phecode
794
Abnormal results of other function studies
Abnormal results of other function studies (bladder, pancreas, placenta, spleen, etc)
 Symptoms 0.94 0.783 – 1.13 0.51 120 1198 all phecode
797 Shock Symptoms 0.965 0.825 – 1.13 0.662 156 1559 all phecode
797.1 Cardiogenic shock Symptoms 1.07 0.885 – 1.3 0.471 102 1020 all phecode
798 Malaise and fatigue Symptoms 1.01 0.973 – 1.04 0.676 3408 34103 all phecode
798.1 Chronic fatigue syndrome Symptoms 1.05 0.963 – 1.14 0.274 591 5913 all phecode
800 Fracture of lower limb Injuries & Poisonings 1.04 1.01 – 1.06 0.00223 7035 70329 all phecode
800.1 Fracture of neck of femur Injuries & Poisonings 0.978 0.932 – 1.03 0.371 1815 18152 all phecode
800.2 Fracture of unspecified part of femur Injuries & Poisonings 1.18 1.01 – 1.38 0.0354 170 1693 all phecode
800.3 Fracture of tibia and fibula Injuries & Poisonings 1.07 1.02 – 1.11 0.0049 2158 21577 all phecode
800.4 Fracture of patella Injuries & Poisonings 1.06 0.985 – 1.14 0.119 766 7661 all phecode
801 Fracture of ankle and foot Injuries & Poisonings 1.01 0.969 – 1.06 0.574 2205 22041 all phecode
801.1 Fracture of foot Injuries & Poisonings 1.03 0.986 – 1.08 0.168 1835 18346 all phecode
802 Fracture of pelvis Injuries & Poisonings 1.04 0.963 – 1.12 0.324 718 7185 all phecode
803 Fracture of upper limb Injuries & Poisonings 0.995 0.973 – 1.02 0.687 8288 82880 all phecode
803.1 Fracture of humerus Injuries & Poisonings 1.01 0.957 – 1.06 0.813 1691 16883 all phecode
803.2 Fracture of radius and ulna Injuries & Poisonings 0.989 0.961 – 1.02 0.437 5215 52171 all phecode
803.3 Fracture of clavicle or scapula Injuries & Poisonings 0.995 0.944 – 1.05 0.841 1518 15186 all phecode
804 Fracture of hand or wrist Injuries & Poisonings 0.989 0.954 – 1.02 0.536 3339 33384 all phecode
805
Fracture of vertebral column without mention of
Fracture of vertebral column without mention of spinal cord injury
 Injuries & Poisonings 1.06 1 – 1.12 0.046 1358 13565 all phecode
807 Fracture of ribs Injuries & Poisonings 1.01 0.936 – 1.08 0.859 776 7752 all phecode
809 Fracture of unspecified bones Injuries & Poisonings 1.03 0.974 – 1.09 0.297 1300 12998 all phecode
817 Concussion Injuries & Poisonings 0.951 0.835 – 1.08 0.454 243 2428 all phecode
818 Intracranial hemorrhage (injury) Injuries & Poisonings 1.01 0.925 – 1.11 0.802 522 5213 all phecode
819
Skull and face fracture and other intercranial
Skull and face fracture and other intercranial injury
 Injuries & Poisonings 1.01 0.969 – 1.05 0.73 2957 29596 all phecode
823 Torus fracture Injuries & Poisonings 1.05 0.999 – 1.1 0.0528 1673 16710 all phecode
830 Dislocation Injuries & Poisonings 1.01 0.964 – 1.05 0.738 2088 20872 all phecode
835 Internal derangement of knee Injuries & Poisonings 1 0.985 – 1.02 0.892 15221 152247 all phecode
836 Traumatic arthropathy Injuries & Poisonings 1 0.917 – 1.09 0.972 526 5267 all phecode
840 Sprains and strains Injuries & Poisonings 1.04 0.949 – 1.15 0.386 470 4697 all phecode
850 Hemorrhage or hematoma complicating a procedure Injuries & Poisonings 1.02 0.991 – 1.05 0.177 5259 52626 all phecode
851
Complications of transplants and reattached
Complications of transplants and reattached limbs
 Injuries & Poisonings 0.926 0.787 – 1.09 0.351 157 1567 all phecode
853 Complication of colostomy or enterostomy Injuries & Poisonings 0.965 0.881 – 1.06 0.446 501 5010 all phecode
854
Complications of cardiac/vascular device
Complications of cardiac/vascular device, implant, and graft
 Injuries & Poisonings 1.02 0.975 – 1.07 0.348 1826 18238 all phecode
857
Mechanical complication of unspecified
Mechanical complication of unspecified genitourinary device, implant, and graft
 Injuries & Poisonings 0.999 0.942 – 1.06 0.966 1241 12418 all phecode
858 Complication of internal orthopedic device Injuries & Poisonings 1.02 0.984 – 1.06 0.281 3158 31607 all phecode
859
Complication due to other implant and internal
Complication due to other implant and internal device
 Injuries & Poisonings 0.991 0.956 – 1.03 0.612 3259 32599 all phecode
860 Bone marrow or stem cell transplant Neoplasms 1.14 0.893 – 1.46 0.294 68 680 all phecode
870 Open wounds of head; neck; and trunk Injuries & Poisonings 1 0.966 – 1.03 0.989 3502 35062 all phecode
870.1 Open wound or laceration of eye or eyelid Injuries & Poisonings 0.947 0.837 – 1.07 0.388 272 2713 all phecode
870.2 Open wound of ear Injuries & Poisonings 0.94 0.814 – 1.08 0.395 196 1949 all phecode
870.3 Other open wound of head and face Injuries & Poisonings 0.998 0.961 – 1.04 0.932 2904 29085 all phecode
870.4 Open wound of nose and sinus Injuries & Poisonings 0.93 0.813 – 1.06 0.287 220 2199 all phecode
870.6 Open wound of neck Injuries & Poisonings 1.06 0.843 – 1.34 0.608 68 678 all phecode
871 Open wounds of extremities Injuries & Poisonings 1.01 0.976 – 1.04 0.653 4063 40648 all phecode
871.1 Open wound of hand except finger(s) Injuries & Poisonings 1.08 0.819 – 1.41 0.601 53 530 all phecode
871.2 Open wound of finger(s) Injuries & Poisonings 1.06 0.855 – 1.31 0.602 91 900 all phecode
871.3 Open wound of foot except toe(s) alone Injuries & Poisonings 1 0.862 – 1.16 0.993 178 1785 all phecode
872 Traumatic amputation Injuries & Poisonings 0.956 0.871 – 1.05 0.346 475 4742 all phecode
873 Broken tooth Injuries & Poisonings 1.04 0.911 – 1.19 0.547 229 2289 all phecode
874 Complication of amputation stump Injuries & Poisonings 1.16 0.99 – 1.36 0.0661 169 1710 all phecode
905
Late effects of musculoskeletal and connective
Late effects of musculoskeletal and connective tissue injuries
 Injuries & Poisonings 0.929 0.79 – 1.09 0.371 157 1567 all phecode
907 Injuries to the nervous system Injuries & Poisonings 0.968 0.915 – 1.02 0.265 1314 13140 all phecode
915 Superficial injury without mention of infection Injuries & Poisonings 0.988 0.957 – 1.02 0.438 4260 42663 all phecode
916 Contusion Injuries & Poisonings 1.01 0.952 – 1.06 0.85 1450 14506 all phecode
930 Allergic reaction to food Injuries & Poisonings 0.93 0.797 – 1.09 0.363 179 1807 all phecode
938 Dermatitis due to solar radiation Injuries & Poisonings 0.958 0.864 – 1.06 0.415 389 3899 all phecode
938.2 Chronic dermatitis due to solar radiation Injuries & Poisonings 0.972 0.856 – 1.1 0.661 252 2530 all phecode
939
Atopic/contact dermatitis due to other or
Atopic/contact dermatitis due to other or unspecified
 Dermatologic 0.965 0.923 – 1.01 0.12 2094 20961 all phecode
941 Adverse reaction to serum or vaccine Injuries & Poisonings 0.954 0.831 – 1.1 0.503 225 2249 all phecode
942 Infusion and transfusion reaction Injuries & Poisonings 1.02 0.836 – 1.24 0.863 104 1038 all phecode
946 Anaphylactic shock NOS Injuries & Poisonings 1.05 0.964 – 1.15 0.252 550 5509 all phecode
947 Urticaria Injuries & Poisonings 1.07 0.962 – 1.19 0.21 371 3707 all phecode
949 Allergies, other Injuries & Poisonings 1.02 0.924 – 1.13 0.675 397 3989 all phecode
952
Spinal cord injury without evidence of spinal
Spinal cord injury without evidence of spinal bone injury
 Injuries & Poisonings 1.11 1 – 1.22 0.0421 423 4224 all phecode
957 Injury to other and unspecified nerves Injuries & Poisonings 1.09 0.96 – 1.24 0.186 269 2698 all phecode
958
Certain early complications of trauma or
Certain early complications of trauma or procedure
 Injuries & Poisonings 0.942 0.859 – 1.03 0.21 491 4926 all phecode
958.1 Postoperative shock Injuries & Poisonings 1.07 0.805 – 1.43 0.635 55 555 all phecode
958.2 Traumatic and surgical subcutaneous emphysema Injuries & Poisonings 0.821 0.651 – 1.04 0.0973 74 740 all phecode
960 Poisoning by antibiotics Injuries & Poisonings 0.999 0.984 – 1.01 0.925 18100 181147 all phecode
960.2 Allergy/adverse effect of penicillin Injuries & Poisonings 0.995 0.979 – 1.01 0.58 15846 158623 all phecode
961 Poisoning by other anti-infectives Injuries & Poisonings 1.05 0.95 – 1.16 0.346 420 4195 all phecode
961.1 Poisoning/allergy of sulfonamides Injuries & Poisonings 1.04 0.967 – 1.11 0.307 869 8703 all phecode
962 Poisoning by hormones and synthetic substitutes Injuries & Poisonings 1 0.902 – 1.12 0.93 371 3707 all phecode
962.3
Hormones and synthetic substitutes causing
Hormones and synthetic substitutes causing adverse effects in therapeutic use
 Injuries & Poisonings 1.01 0.906 – 1.13 0.86 364 3638 all phecode
963 Poisoning by primarily systemic agents Injuries & Poisonings 1.06 0.919 – 1.21 0.442 223 2228 all phecode
964
Poisoning by agents primarily affecting blood
Poisoning by agents primarily affecting blood constituents
 Injuries & Poisonings 0.947 0.839 – 1.07 0.381 282 2830 all phecode
964.1 Anticoagulants causing adverse effects Injuries & Poisonings 0.957 0.846 – 1.08 0.486 276 2770 all phecode
965
Poisoning by analgesics, antipyretics, and
Poisoning by analgesics, antipyretics, and antirheumatics
 Injuries & Poisonings 1.02 0.994 – 1.05 0.133 6082 60875 all phecode
965.1
Opiates and related narcotics causing adverse
Opiates and related narcotics causing adverse effects in therapeutic use
 Injuries & Poisonings 0.989 0.93 – 1.05 0.723 1144 11447 all phecode
965.2
Antirheumatics causing adverse effects in
Antirheumatics causing adverse effects in therapeutic use
 Injuries & Poisonings 0.961 0.874 – 1.06 0.406 476 4767 all phecode
965.3
Salicylates causing adverse effects in
Salicylates causing adverse effects in therapeutic use
 Injuries & Poisonings 1.06 0.954 – 1.17 0.297 403 4045 all phecode
966
Poisoning by anticonvulsants and
Poisoning by anticonvulsants and anti-Parkinsonism drugs
 Injuries & Poisonings 1.03 0.943 – 1.13 0.474 512 5123 all phecode
967
Adverse effects of sedatives or other central
Adverse effects of sedatives or other central nervous system depressants and anesthetics
 Injuries & Poisonings 1.03 0.942 – 1.12 0.568 583 5843 all phecode
969 Poisoning by psychotropic agents Injuries & Poisonings 1.03 0.979 – 1.07 0.293 1950 19519 all phecode
971
Poisoning by drugs primarily affecting the
Poisoning by drugs primarily affecting the autonomic nervous system
 Injuries & Poisonings 1.07 0.927 – 1.24 0.347 190 1908 all phecode
972
Poisoning by agents primarily affecting the
Poisoning by agents primarily affecting the cardiovascular system
 Injuries & Poisonings 1.17 1.03 – 1.32 0.0136 271 2717 all phecode
972.6 Antihypertensive agents causing adverse effects Injuries & Poisonings 0.99 0.787 – 1.25 0.931 84 849 all phecode
973
Poisoning by agents primarily affecting the
Poisoning by agents primarily affecting the gastrointestinal system
 Injuries & Poisonings 1.01 0.829 – 1.22 0.94 108 1080 all phecode
974
Poisoning by water, mineral, and uric acid
Poisoning by water, mineral, and uric acid metabolism drugs
 Injuries & Poisonings 1.12 0.925 – 1.36 0.243 101 1018 all phecode
975
Poisoning by agents primarily acting on the
Poisoning by agents primarily acting on the smooth and skeletal muscles and respiratory system
 Injuries & Poisonings 0.992 0.761 – 1.29 0.95 64 640 all phecode
976
Poisoning by agents primarily affecting skin &
Poisoning by agents primarily affecting skin & mucous membrane, ophthalmological, otorhinolaryngological, & dental drugs
 Injuries & Poisonings 1.06 0.82 – 1.37 0.653 58 580 all phecode
977 Personal history of allergy to medicinal agents Injuries & Poisonings 0.909 0.796 – 1.04 0.157 234 2337 all phecode
979 Adverse drug events and drug allergies Injuries & Poisonings 0.992 0.917 – 1.07 0.843 698 6966 all phecode
981
Toxic effect of (non-ethyl) alcohol and
Toxic effect of (non-ethyl) alcohol and petroleum and other solvents
 Injuries & Poisonings 0.981 0.849 – 1.13 0.792 200 1999 all phecode
986 Toxic effect of carbon monoxide Injuries & Poisonings 0.935 0.721 – 1.21 0.613 62 620 all phecode
987 Toxic effect of other gases, fumes, or vapors Injuries & Poisonings 1.06 0.874 – 1.3 0.537 105 1049 all phecode
988 Toxic effect of noxious substances eaten as food Injuries & Poisonings 0.827 0.68 – 1.01 0.0579 111 1128 all phecode
989
Toxic effect of other substances, chiefly
Toxic effect of other substances, chiefly nonmedicinal as to source
 Injuries & Poisonings 0.89 0.712 – 1.11 0.304 89 890 all phecode
990 Effects radiation NOS Injuries & Poisonings 1 0.969 – 1.04 0.797 3113 31140 all phecode
994 Sepsis and SIRS Injuries & Poisonings 0.976 0.94 – 1.01 0.208 3028 30268 all phecode
994.2 Sepsis Injuries & Poisonings 0.976 0.94 – 1.01 0.208 3028 30268 all phecode
008 Intestinal infection Infectious Diseases 1 0.982 – 1.03 0.696 7801 83500 exclusion phecode
008.5 Bacterial enteritis Infectious Diseases 1.02 0.98 – 1.07 0.306 2432 25627 exclusion phecode
008.52 Intestinal infection due to C. difficile Infectious Diseases 0.97 0.891 – 1.06 0.489 575 6126 exclusion phecode
008.6 Viral Enteritis Infectious Diseases 1.03 0.958 – 1.11 0.398 743 8128 exclusion phecode
008.7 Intestinal infection due to protozoa Infectious Diseases 1.21 0.907 – 1.6 0.198 53 526 exclusion phecode
010 Tuberculosis Infectious Diseases 1.1 0.933 – 1.3 0.257 154 1538 exclusion phecode
038 Septicemia Infectious Diseases 0.96 0.928 – 0.994 0.0216 3616 39127 exclusion phecode
038.1 Gram negative septicemia Infectious Diseases 0.987 0.914 – 1.07 0.746 733 7938 exclusion phecode
038.2 Gram positive septicemia Infectious Diseases 0.899 0.813 – 0.994 0.0377 413 4672 exclusion phecode
041 Bacterial infection NOS Infectious Diseases 0.979 0.959 – 0.999 0.0352 10505 113294 exclusion phecode
041.1 Staphylococcus infections Infectious Diseases 0.978 0.94 – 1.02 0.276 2641 29478 exclusion phecode
041.2 Streptococcus infection Infectious Diseases 0.957 0.906 – 1.01 0.107 1436 15459 exclusion phecode
041.4 E. coli Infectious Diseases 0.96 0.92 – 1 0.0585 2350 25798 exclusion phecode
053 Herpes zoster Infectious Diseases 1.02 0.921 – 1.14 0.666 370 3849 exclusion phecode
053.1 Herpes zoster with nervous system complications Infectious Diseases 0.943 0.762 – 1.17 0.588 87 886 exclusion phecode
054 Herpes simplex Infectious Diseases 0.908 0.783 – 1.05 0.204 200 1993 exclusion phecode
070 Viral hepatitis Infectious Diseases 0.958 0.878 – 1.04 0.332 527 5587 exclusion phecode
070.1 Viral hepatitis A Infectious Diseases 1.14 0.883 – 1.48 0.307 63 653 exclusion phecode
070.2 Viral hepatitis B Infectious Diseases 1.04 0.867 – 1.24 0.69 118 1254 exclusion phecode
070.3 Viral hepatitis C Infectious Diseases 0.852 0.746 – 0.973 0.0185 234 2444 exclusion phecode
070.4 Chronic hepatitis Infectious Diseases 0.928 0.812 – 1.06 0.267 243 2621 exclusion phecode
070.9 Hepatitis NOS Infectious Diseases 1.01 0.901 – 1.13 0.857 317 4032 exclusion phecode
071 Human immunodeficiency virus [HIV] disease Infectious Diseases 0.996 0.839 – 1.18 0.966 137 1384 exclusion phecode
071.1 HIV infection, symptomatic Infectious Diseases 1.03 0.844 – 1.24 0.802 107 1090 exclusion phecode
078 Viral warts & HPV Infectious Diseases 1.05 0.983 – 1.12 0.145 927 9515 exclusion phecode
079 Viral infection Infectious Diseases 0.976 0.937 – 1.02 0.244 2526 26371 exclusion phecode
079.1 Varicella infection Infectious Diseases 1.12 0.871 – 1.43 0.387 61 613 exclusion phecode
080 Postoperative infection Infectious Diseases 0.98 0.948 – 1.01 0.224 3928 42268 exclusion phecode
081
Infection/inflammation of internal prosthetic
Infection/inflammation of internal prosthetic device; implant; and graft
 Infectious Diseases 0.988 0.946 – 1.03 0.588 2215 23313 exclusion phecode
090
Sexually transmitted infections (not HIV or
Sexually transmitted infections (not HIV or hepatitis)
 Infectious Diseases 1.09 0.843 – 1.42 0.499 60 662 exclusion phecode
1000 Burns Injuries & Poisonings 0.935 0.856 – 1.02 0.142 527 5463 exclusion phecode
1001 Foreign body injury Injuries & Poisonings 1.01 0.948 – 1.07 0.797 1110 11318 exclusion phecode
1002
Symptoms concerning nutrition, metabolism, and
Symptoms concerning nutrition, metabolism, and development
 Injuries & Poisonings 0.999 0.97 – 1.03 0.923 4996 51572 exclusion phecode
1004
Other signs and symptoms involving emotional
Other signs and symptoms involving emotional state
 Injuries & Poisonings 0.926 0.816 – 1.05 0.226 265 2835 exclusion phecode
1005 Other symptoms Injuries & Poisonings 1.01 0.95 – 1.07 0.841 1294 13556 exclusion phecode
1006 Crushing injury Injuries & Poisonings 0.932 0.816 – 1.06 0.298 237 2403 exclusion phecode
1007 Injury to blood vessels Injuries & Poisonings 1.15 1.01 – 1.31 0.0399 236 2392 exclusion phecode
1008 Crushing or internal injury to organs Injuries & Poisonings 0.972 0.909 – 1.04 0.405 944 9490 exclusion phecode
1009 Injury, NOS Injuries & Poisonings 0.985 0.962 – 1.01 0.194 7818 80029 exclusion phecode
1010 Other tests Injuries & Poisonings 0.985 0.957 – 1.01 0.281 5217 55996 exclusion phecode
1011 Complications of surgical and medical procedures Injuries & Poisonings 0.996 0.974 – 1.02 0.742 8339 85978 exclusion phecode
1012 Late effect Injuries & Poisonings 1.23 1.01 – 1.5 0.0391 95 998 exclusion phecode
1013 Asphyxia and hypoxemia Injuries & Poisonings 0.967 0.855 – 1.09 0.595 283 2995 exclusion phecode
1014 Effects of heat, cold and air pressure Injuries & Poisonings 1.1 0.847 – 1.42 0.485 62 622 exclusion phecode
1015 Effects of other external causes Injuries & Poisonings 0.998 0.965 – 1.03 0.884 3770 40032 exclusion phecode
1019
Other ill-defined and unknown causes of
Other ill-defined and unknown causes of morbidity and mortality
 Injuries & Poisonings 1 0.985 – 1.02 0.792 14592 150541 exclusion phecode
110 Dermatophytosis / Dermatomycosis Infectious Diseases 0.974 0.855 – 1.11 0.685 252 2617 exclusion phecode
110.1 Dermatophytosis Infectious Diseases 0.98 0.859 – 1.12 0.762 247 2562 exclusion phecode
110.11 Dermatophytosis of nail Infectious Diseases 0.886 0.692 – 1.13 0.338 72 708 exclusion phecode
110.12 Althete's foot Infectious Diseases 1.03 0.861 – 1.24 0.729 126 1320 exclusion phecode
112 Candidiasis Infectious Diseases 0.974 0.929 – 1.02 0.278 1898 19991 exclusion phecode
117 Mycoses Infectious Diseases 0.986 0.867 – 1.12 0.83 248 2530 exclusion phecode
117.4 Aspergillosis Infectious Diseases 0.999 0.847 – 1.18 0.992 151 1525 exclusion phecode
130 Spirochetal infection Infectious Diseases 0.811 0.641 – 1.03 0.0814 79 764 exclusion phecode
133 Arthropod-borne diseases Infectious Diseases 1.05 0.814 – 1.36 0.697 64 644 exclusion phecode
134 Helminthiases Infectious Diseases 1.11 0.927 – 1.33 0.254 119 1222 exclusion phecode
134.1 Intestinal helminthiases Infectious Diseases 1.1 0.909 – 1.34 0.323 99 1022 exclusion phecode
136 Other infectious and parasitic diseases Infectious Diseases 1.15 0.995 – 1.33 0.0587 189 1924 exclusion phecode
145 Cancer of mouth Neoplasms 1.04 0.955 – 1.13 0.381 608 5992 exclusion phecode
145.2 Cancer of tongue Neoplasms 1.04 0.923 – 1.17 0.517 292 2888 exclusion phecode
145.3 Cancer of major salivary glands Neoplasms 1.06 0.869 – 1.3 0.556 104 996 exclusion phecode
145.5 Cancer of the mouth floor Neoplasms 0.968 0.728 – 1.29 0.824 49 502 exclusion phecode
149 Cancer of larynx, pharynx, nasal cavities Neoplasms 1.02 0.935 – 1.11 0.681 572 5872 exclusion phecode
149.1 Cancer of oropharynx Neoplasms 1.01 0.878 – 1.16 0.878 229 2341 exclusion phecode
149.4 Cancer of larynx Neoplasms 1.08 0.943 – 1.23 0.278 231 2424 exclusion phecode
149.9 Cancer of of nasal cavities Neoplasms 1.04 0.792 – 1.36 0.782 55 543 exclusion phecode
150 Cancer of esophagus Neoplasms 0.892 0.824 – 0.967 0.00529 676 7038 exclusion phecode
151 Cancer of stomach Neoplasms 0.967 0.882 – 1.06 0.472 504 5252 exclusion phecode
153 Colorectal cancer Neoplasms 1.02 0.986 – 1.05 0.284 4216 42788 exclusion phecode
153.2 Colon cancer Neoplasms 1 0.967 – 1.04 0.8 2858 28989 exclusion phecode
153.3
Malignant neoplasm of rectum, rectosigmoid
Malignant neoplasm of rectum, rectosigmoid junction, and anus
 Neoplasms 1.02 0.972 – 1.07 0.448 1984 20217 exclusion phecode
155 Cancer of liver and intrahepatic bile duct Neoplasms 0.899 0.802 – 1.01 0.0661 327 3715 exclusion phecode
155.1 Malignant neoplasm of liver, primary Neoplasms 0.91 0.754 – 1.1 0.324 114 1454 exclusion phecode
157 Pancreatic cancer Neoplasms 1.06 0.975 – 1.16 0.167 576 6096 exclusion phecode
158
Neoplasm of unspecified nature of digestive
Neoplasm of unspecified nature of digestive system
 Neoplasms 0.999 0.934 – 1.07 0.982 967 9951 exclusion phecode
159
Malignant neoplasm of other and ill-defined
Malignant neoplasm of other and ill-defined sites within the digestive organs and peritoneum
 Neoplasms 1.01 0.978 – 1.04 0.637 5079 51987 exclusion phecode
159.2
Malignant neoplasm of small intestine
Malignant neoplasm of small intestine, including duodenum
 Neoplasms 0.931 0.796 – 1.09 0.366 172 1773 exclusion phecode
159.3
Malignant neoplasm of gallbladder and
Malignant neoplasm of gallbladder and extrahepatic bile ducts
 Neoplasms 1.01 0.865 – 1.18 0.91 183 1911 exclusion phecode
159.4
Malignant neoplasm of retroperitoneum and
Malignant neoplasm of retroperitoneum and peritoneum
 Neoplasms 0.835 0.715 – 0.975 0.0228 177 1800 exclusion phecode
164 Cancer of intrathoracic organs Neoplasms 1.04 0.813 – 1.33 0.755 56 562 exclusion phecode
165 Cancer within the respiratory system Neoplasms 0.986 0.946 – 1.03 0.482 2559 26211 exclusion phecode
165.1 Cancer of bronchus; lung Neoplasms 0.973 0.93 – 1.02 0.251 2019 20736 exclusion phecode
170 Cancer of bone and connective tissue Neoplasms 0.969 0.873 – 1.08 0.559 407 4098 exclusion phecode
170.1 Bone cancer Neoplasms 1.03 0.852 – 1.24 0.788 123 1237 exclusion phecode
170.2 Cancer of connective tissue Neoplasms 0.944 0.837 – 1.07 0.355 308 3112 exclusion phecode
172 Skin cancer Neoplasms 0.991 0.973 – 1.01 0.31 12674 126217 exclusion phecode
172.1 Melanomas of skin, dx or hx Neoplasms 0.967 0.928 – 1.01 0.104 2538 25249 exclusion phecode
172.11 Melanomas of skin Neoplasms 0.966 0.927 – 1.01 0.0953 2568 25565 exclusion phecode
172.2 Other non-epithelial cancer of skin Neoplasms 0.993 0.973 – 1.01 0.48 10324 102723 exclusion phecode
172.3 Carcinoma in situ of skin Neoplasms 0.944 0.868 – 1.03 0.183 617 6227 exclusion phecode
173 Neoplasm of uncertain behavior of skin Neoplasms 0.954 0.815 – 1.12 0.559 169 1726 exclusion phecode
174 Breast cancer Neoplasms 1.01 0.988 – 1.03 0.472 12089 121554 exclusion phecode
174.1 Breast cancer [female] Neoplasms 1.01 0.988 – 1.03 0.478 11895 119587 exclusion phecode
174.11 Malignant neoplasm of female breast Neoplasms 1 0.986 – 1.02 0.619 11201 112851 exclusion phecode
174.3 Neoplasm of uncertain behavior of breast Neoplasms 1.08 0.88 – 1.33 0.45 109 1103 exclusion phecode
175 Acquired absence of breast Neoplasms 1 0.96 – 1.05 0.907 2267 23059 exclusion phecode
180 Cervical cancer and dysplasia Neoplasms 0.99 0.946 – 1.04 0.659 2101 21052 exclusion phecode
180.1 Cervical cancer Neoplasms 0.97 0.853 – 1.1 0.641 263 2628 exclusion phecode
180.3
Cervical intraepithelial neoplasia [CIN]
Cervical intraepithelial neoplasia [CIN] [Cervical dysplasia]
 Neoplasms 0.995 0.95 – 1.04 0.819 2006 20110 exclusion phecode
182 Malignant neoplasm of uterus Neoplasms 0.952 0.896 – 1.01 0.112 1172 12252 exclusion phecode
184 Cancer of other female genital organs Neoplasms 1.02 0.962 – 1.08 0.542 1317 13206 exclusion phecode
184.1
Malignant neoplasm of ovary and other uterine
Malignant neoplasm of ovary and other uterine adnexa
 Neoplasms 0.993 0.928 – 1.06 0.849 926 9253 exclusion phecode
184.11 Malignant neoplasm of ovary Neoplasms 1 0.937 – 1.08 0.916 899 8989 exclusion phecode
184.2
Cancer of other female genital organs
Cancer of other female genital organs (excluding uterus and ovary)
 Neoplasms 0.997 0.884 – 1.13 0.965 292 2931 exclusion phecode
185 Cancer of prostate Neoplasms 1.04 1.01 – 1.07 0.00333 5561 53416 exclusion phecode
187 Cancer of other male genital organs Neoplasms 1.05 0.95 – 1.17 0.325 409 4176 exclusion phecode
187.1
Malignant neoplasm of unspecified male genital
Malignant neoplasm of unspecified male genital organ
 Neoplasms 0.82 0.629 – 1.07 0.14 61 652 exclusion phecode
187.2 Malignant neoplasm of testis Neoplasms 1.03 0.904 – 1.17 0.679 262 2693 exclusion phecode
187.8
Neoplasm of uncertain behavior of male genital
Neoplasm of uncertain behavior of male genital organs
 Neoplasms 1.23 1 – 1.51 0.0481 101 1018 exclusion phecode
189
Cancer of urinary organs (incl. kidney and
Cancer of urinary organs (incl. kidney and bladder)
 Neoplasms 1.02 0.99 – 1.06 0.172 3716 38439 exclusion phecode
189.1 Cancer of kidney and renal pelvis Neoplasms 1.01 0.947 – 1.08 0.742 964 10024 exclusion phecode
189.11 Malignant neoplasm of kidney, except pelvis Neoplasms 1.02 0.951 – 1.09 0.637 924 9659 exclusion phecode
189.12 Malignant neoplasm of renal pelvis Neoplasms 0.908 0.696 – 1.18 0.477 62 608 exclusion phecode
189.2 Cancer of bladder Neoplasms 1.04 0.993 – 1.08 0.101 2133 22199 exclusion phecode
189.21 Malignant neoplasm of bladder Neoplasms 1.03 0.983 – 1.08 0.217 1895 19748 exclusion phecode
189.4 Malignant neoplasm of other urinary organs Neoplasms 1.01 0.848 – 1.2 0.91 134 1315 exclusion phecode
190 Cancer of eye Neoplasms 1.04 0.891 – 1.22 0.608 161 1637 exclusion phecode
191
Manlignant and unknown neoplasms of brain and
Manlignant and unknown neoplasms of brain and nervous system
 Neoplasms 1.04 0.958 – 1.13 0.361 649 6455 exclusion phecode
191.1 Cancer of brain and nervous system Neoplasms 1.07 0.975 – 1.16 0.16 536 5303 exclusion phecode
191.11 Cancer of brain Neoplasms 1.08 0.984 – 1.18 0.108 498 4914 exclusion phecode
193 Thyroid cancer Neoplasms 0.984 0.878 – 1.1 0.779 320 3328 exclusion phecode
194 Cancer of other endocrine glands Neoplasms 0.856 0.678 – 1.08 0.192 81 896 exclusion phecode
195 Cancer, suspected or other Neoplasms 1 0.988 – 1.02 0.612 15717 155208 exclusion phecode
195.1 Malignant neoplasm, other Neoplasms 1 0.986 – 1.02 0.798 15068 149539 exclusion phecode
197 Chemotherapy Neoplasms 1 0.986 – 1.02 0.895 19777 201681 exclusion phecode
198 Secondary malignant neoplasm Neoplasms 0.996 0.974 – 1.02 0.716 8818 89754 exclusion phecode
198.1 Secondary malignancy of lymph nodes Neoplasms 0.981 0.952 – 1.01 0.189 4996 50682 exclusion phecode
198.2 Secondary malignancy of respiratory organs Neoplasms 0.956 0.914 – 1 0.0505 2085 21259 exclusion phecode
198.3
Secondary malignant neoplasm of digestive
Secondary malignant neoplasm of digestive systems
 Neoplasms 0.97 0.919 – 1.02 0.275 1433 14603 exclusion phecode
198.4 Secondary malignant neoplasm of liver Neoplasms 0.982 0.942 – 1.02 0.401 2439 24960 exclusion phecode
198.5 Secondary malignancy of brain/spine Neoplasms 1.05 0.973 – 1.12 0.226 798 7968 exclusion phecode
198.6 Secondary malignancy of bone Neoplasms 1.02 0.974 – 1.07 0.405 1979 20192 exclusion phecode
198.7 Secondary malignant neoplasm of skin Neoplasms 0.981 0.837 – 1.15 0.817 174 1775 exclusion phecode
199 Neoplasm of uncertain behavior Neoplasms 1.01 0.952 – 1.07 0.793 1319 13484 exclusion phecode
199.4 Neurofibromatosis Neoplasms 0.977 0.787 – 1.21 0.83 91 905 exclusion phecode
200 Myeloproliferative disease Neoplasms 1.07 1 – 1.15 0.0404 889 9257 exclusion phecode
200.1 Polycythemia vera Neoplasms 1.08 0.967 – 1.21 0.169 331 3575 exclusion phecode
201 Hodgkin's disease Neoplasms 0.816 0.712 – 0.934 0.00331 240 2447 exclusion phecode
202 Cancer of other lymphoid, histiocytic tissue Neoplasms 0.996 0.953 – 1.04 0.862 2095 21255 exclusion phecode
202.2 Non-Hodgkins lymphoma Neoplasms 0.988 0.94 – 1.04 0.647 1669 16881 exclusion phecode
202.21 Nodular lymphoma Neoplasms 1.01 0.902 – 1.12 0.911 340 3414 exclusion phecode
202.24 Large cell lymphoma Neoplasms 1.02 0.932 – 1.11 0.689 538 5448 exclusion phecode
204 Leukemia Neoplasms 1.04 0.983 – 1.09 0.191 1528 15471 exclusion phecode
204.1 Lymphoid leukemia Neoplasms 1.14 1.05 – 1.25 0.0025 521 5374 exclusion phecode
204.11 Lymphoid leukemia, acute Neoplasms 1.04 0.792 – 1.36 0.789 52 529 exclusion phecode
204.12 Lymphoid leukemia, chronic Neoplasms 1.13 1.03 – 1.24 0.0113 453 4700 exclusion phecode
204.2 Myeloid leukemia Neoplasms 1.01 0.911 – 1.11 0.909 436 4302 exclusion phecode
204.21 Myeloid leukemia, acute Neoplasms 1 0.892 – 1.13 0.969 311 3041 exclusion phecode
204.22 Myeloid leukemia, chronic Neoplasms 1.03 0.867 – 1.23 0.72 137 1359 exclusion phecode
204.4 Multiple myeloma Neoplasms 0.949 0.867 – 1.04 0.248 517 5179 exclusion phecode
208 Benign neoplasm of colon Neoplasms 1 0.989 – 1.02 0.601 18008 180018 exclusion phecode
210 Benign neoplasm of lip, oral cavity, and pharynx Neoplasms 1.05 0.978 – 1.12 0.181 901 9212 exclusion phecode
211
Benign neoplasm of other parts of digestive
Benign neoplasm of other parts of digestive system
 Neoplasms 1 0.974 – 1.03 0.832 4765 49410 exclusion phecode
212
Benign neoplasm of respiratory and
Benign neoplasm of respiratory and intrathoracic organs
 Neoplasms 0.899 0.802 – 1.01 0.0687 319 3256 exclusion phecode
213 Benign neoplasm of bone and articular cartilage Neoplasms 1.02 0.908 – 1.15 0.736 304 3023 exclusion phecode
214 Lipoma Neoplasms 1.01 0.988 – 1.04 0.29 5824 58607 exclusion phecode
214.1 Lipoma of skin and subcutaneous tissue Neoplasms 1.01 0.981 – 1.04 0.457 4307 43303 exclusion phecode
215
Other benign neoplasm of connective and other
Other benign neoplasm of connective and other soft tissue
 Neoplasms 0.99 0.929 – 1.06 0.761 1055 10460 exclusion phecode
216 Benign neoplasm of skin Neoplasms 1.01 0.983 – 1.03 0.581 7257 72741 exclusion phecode
217 Vascular hamartomas and non-neoplastic nevi Neoplasms 1.01 0.925 – 1.1 0.859 587 5954 exclusion phecode
217.1 Nevus, non-neoplastic Neoplasms 1.04 0.95 – 1.13 0.414 551 5598 exclusion phecode
218 Benign neoplasm of uterus Neoplasms 1 0.982 – 1.02 0.809 9606 96769 exclusion phecode
218.1 Uterine leiomyoma Neoplasms 1.01 0.987 – 1.03 0.463 9813 98814 exclusion phecode
218.2 Other benign neoplasm of uterus Neoplasms 0.939 0.839 – 1.05 0.275 336 3427 exclusion phecode
220 Benign neoplasm of ovary Neoplasms 1.01 0.953 – 1.07 0.798 1358 13942 exclusion phecode
221 Benign neoplasm of other female genital organs Neoplasms 1.06 0.916 – 1.22 0.445 200 2113 exclusion phecode
222 Benign neoplasm of male genital organs Neoplasms 0.957 0.812 – 1.13 0.598 148 1462 exclusion phecode
223
Benign neoplasm of kidney and other urinary
Benign neoplasm of kidney and other urinary organs
 Neoplasms 0.97 0.821 – 1.15 0.724 156 1600 exclusion phecode
224 Benign neoplasm of eye Neoplasms 0.923 0.764 – 1.12 0.41 114 1213 exclusion phecode
224.1 Benign neoplasm of eye, uveal Neoplasms 1.02 0.776 – 1.34 0.891 56 632 exclusion phecode
225
Benign neoplasm of brain and other parts of
Benign neoplasm of brain and other parts of nervous system
 Neoplasms 0.961 0.892 – 1.04 0.306 765 7697 exclusion phecode
225.1
Benign neoplasm of brain, cranial nerves
Benign neoplasm of brain, cranial nerves, meninges
 Neoplasms 0.949 0.879 – 1.03 0.186 726 7322 exclusion phecode
225.2 Benign neoplasm of spinal cord, meninges Neoplasms 1.04 0.8 – 1.36 0.765 55 565 exclusion phecode
226 Benign neoplasm of thyroid glands Neoplasms 0.997 0.876 – 1.14 0.963 251 2537 exclusion phecode
227
Benign neoplasm of other endocrine glands and
Benign neoplasm of other endocrine glands and related structures
 Neoplasms 0.961 0.892 – 1.03 0.289 757 8145 exclusion phecode
227.1 Benign neoplasm of adrenal gland Neoplasms 1.07 0.912 – 1.26 0.407 153 1741 exclusion phecode
227.2 Benign neoplasm of parathyroid gland Neoplasms 1.02 0.91 – 1.13 0.784 338 3497 exclusion phecode
227.3
Benign neoplasm of pituitary gland and
Benign neoplasm of pituitary gland and craniopharyngeal duct (pouch)
 Neoplasms 0.877 0.772 – 0.996 0.0429 272 2944 exclusion phecode
228 Hemangioma and lymphangioma, any site Neoplasms 0.99 0.939 – 1.04 0.701 1494 15077 exclusion phecode
229 Benign neoplasm of unspecified sites Neoplasms 0.965 0.925 – 1.01 0.11 2281 22844 exclusion phecode
240 Simple and unspecified goiter Endocrine/metabolic 0.973 0.891 – 1.06 0.531 554 5744 exclusion phecode
241 Nontoxic nodular goiter Endocrine/metabolic 0.975 0.916 – 1.04 0.438 1055 10605 exclusion phecode
241.1 Nontoxic uninodular goiter Endocrine/metabolic 1.01 0.92 – 1.12 0.791 453 4518 exclusion phecode
241.2 Nontoxic multinodular goiter Endocrine/metabolic 0.955 0.882 – 1.04 0.266 641 6466 exclusion phecode
242 Thyrotoxicosis with or without goiter Endocrine/metabolic 1.02 0.97 – 1.07 0.441 1673 17648 exclusion phecode
242.1 Graves' disease Endocrine/metabolic 0.975 0.882 – 1.08 0.62 418 4347 exclusion phecode
242.2 Toxic multinodular goiter Endocrine/metabolic 0.965 0.776 – 1.2 0.748 86 869 exclusion phecode
242.3 Exophthalmos Endocrine/metabolic 0.916 0.76 – 1.1 0.357 126 1301 exclusion phecode
244 Hypothyroidism Endocrine/metabolic 1.01 0.99 – 1.03 0.423 13227 138345 exclusion phecode
244.1 Secondary hypothyroidism Endocrine/metabolic 0.989 0.928 – 1.05 0.742 1001 10545 exclusion phecode
244.2 Acquired hypothyroidism Endocrine/metabolic 0.94 0.754 – 1.17 0.585 87 957 exclusion phecode
244.4 Hypothyroidism NOS Endocrine/metabolic 1.01 0.989 – 1.03 0.45 12609 132481 exclusion phecode
245 Thyroiditis Endocrine/metabolic 0.985 0.869 – 1.12 0.817 272 2761 exclusion phecode
245.2 Chronic thyroiditis Endocrine/metabolic 1 0.868 – 1.16 0.977 206 2085 exclusion phecode
245.21 Chronic lymphocytic thyroiditis Endocrine/metabolic 0.995 0.86 – 1.15 0.943 201 2015 exclusion phecode
246 Other disorders of thyroid Endocrine/metabolic 1.01 0.904 – 1.12 0.92 371 3790 exclusion phecode
250 Diabetes mellitus Endocrine/metabolic 1.23 1.2 – 1.26 1.23e-55 5756 181935 exclusion phecode
250.1 Type 1 diabetes Endocrine/metabolic 1.09 0.94 – 1.26 0.256 172 27032 exclusion phecode
250.11 Type 1 diabetes with ketoacidosis Endocrine/metabolic 0.805 0.485 – 1.34 0.403 12 2342 exclusion phecode
250.12 Type 1 diabetes with renal manifestations Endocrine/metabolic 0.644 0.262 – 1.58 0.338 1 750 exclusion phecode
250.13 Type 1 diabetes with ophthalmic manifestations Endocrine/metabolic 1.67 0.875 – 3.2 0.12 6 4637 exclusion phecode
250.14 Type 1 diabetes with neurological manifestations Endocrine/metabolic 1.56 0.757 – 3.23 0.227 3 1587 exclusion phecode
250.2 Type 2 diabetes Endocrine/metabolic 1.27 1.23 – 1.3 6.62e-61 4878 166402 exclusion phecode
250.21 Type 2 diabetes with ketoacidosis Endocrine/metabolic 1.68 1.09 – 2.59 0.0177 12 1018 exclusion phecode
250.22 Type 2 diabetes with renal manifestations Endocrine/metabolic 0.939 0.564 – 1.56 0.809 10 1969 exclusion phecode
250.23 Type 2 diabetes with ophthalmic manifestations Endocrine/metabolic 1.4 1.07 – 1.85 0.0152 46 9635 exclusion phecode
250.24 Type 2 diabetes with neurological manifestations Endocrine/metabolic 1.06 0.719 – 1.55 0.78 21 4949 exclusion phecode
250.4 Abnormal glucose Endocrine/metabolic 1.17 1.06 – 1.29 0.00169 423 6683 exclusion phecode
250.41 Impaired fasting glucose Endocrine/metabolic 1.14 0.983 – 1.31 0.0838 186 2598 exclusion phecode
250.42 Other abnormal glucose Endocrine/metabolic 1.19 1.05 – 1.35 0.0078 240 4099 exclusion phecode
250.5 Glycosuria or Acetonuria Endocrine/metabolic 1.03 0.839 – 1.26 0.789 93 1287 exclusion phecode
250.6 Polyneuropathy in diabetes Endocrine/metabolic 0.983 0.623 – 1.55 0.942 14 3419 exclusion phecode
250.7 Diabetic retinopathy Endocrine/metabolic 1.14 0.915 – 1.42 0.242 76 12416 exclusion phecode
251.1 Hypoglycemia Endocrine/metabolic 0.945 0.838 – 1.07 0.356 272 9153 exclusion phecode
252 Disorders of parathyroid gland Endocrine/metabolic 0.941 0.874 – 1.01 0.105 768 8265 exclusion phecode
252.1 Hyperparathyroidism Endocrine/metabolic 0.923 0.854 – 0.998 0.044 685 7393 exclusion phecode
252.2 Hypoparathyroidism Endocrine/metabolic 1.09 0.906 – 1.31 0.365 124 1345 exclusion phecode
253
Disorders of the pituitary gland and its
Disorders of the pituitary gland and its hypothalamic control
 Endocrine/metabolic 0.962 0.883 – 1.05 0.373 585 6425 exclusion phecode
253.1 Pituitary hyperfunction Endocrine/metabolic 0.89 0.755 – 1.05 0.164 162 1772 exclusion phecode
253.11 Acromegaly and gigantism Endocrine/metabolic 0.888 0.706 – 1.12 0.31 82 901 exclusion phecode
253.2 Pituitary hypofunction Endocrine/metabolic 1.02 0.884 – 1.17 0.809 216 2443 exclusion phecode
253.3 Diabetes insipidus Endocrine/metabolic 0.859 0.672 – 1.1 0.224 70 868 exclusion phecode
253.7 Other disorders of neurohypophysis Endocrine/metabolic 1.01 0.846 – 1.21 0.905 137 1477 exclusion phecode
255 Disorders of adrenal glands Endocrine/metabolic 1.01 0.922 – 1.1 0.876 539 6034 exclusion phecode
255.1 Adrenal hyperfunction Endocrine/metabolic 1.13 0.952 – 1.33 0.165 142 1704 exclusion phecode
255.11 Cushing's syndrome Endocrine/metabolic 1.04 0.83 – 1.3 0.734 79 984 exclusion phecode
255.12 Hyperaldosteronism Endocrine/metabolic 1.28 0.999 – 1.64 0.0514 62 724 exclusion phecode
255.2 Adrenal hypofunction Endocrine/metabolic 0.91 0.809 – 1.02 0.119 310 3436 exclusion phecode
255.21 Glucocorticoid deficiency Endocrine/metabolic 0.914 0.812 – 1.03 0.136 309 3426 exclusion phecode
256 Ovarian dysfunction Endocrine/metabolic 0.891 0.779 – 1.02 0.0896 223 2355 exclusion phecode
256.4 Polycystic ovaries Endocrine/metabolic 0.92 0.796 – 1.06 0.254 192 2054 exclusion phecode
257 Testicular dysfunction Endocrine/metabolic 1.02 0.853 – 1.21 0.861 134 1510 exclusion phecode
257.1 Testicular hypofunction Endocrine/metabolic 1.06 0.885 – 1.27 0.533 125 1437 exclusion phecode
258 Iatrogenic endocrine disorders Endocrine/metabolic 1 0.795 – 1.27 0.969 80 958 exclusion phecode
259 Other endocrine disorders Endocrine/metabolic 0.976 0.818 – 1.17 0.792 133 1439 exclusion phecode
260 Protein-calorie malnutrition Endocrine/metabolic 1.03 0.889 – 1.19 0.695 185 1908 exclusion phecode
260.1 Cachexia Endocrine/metabolic 1.11 0.826 – 1.5 0.483 46 478 exclusion phecode
260.6 Anorexia Endocrine/metabolic 0.952 0.883 – 1.03 0.201 754 7811 exclusion phecode
261 Vitamin deficiency Endocrine/metabolic 1.03 0.969 – 1.1 0.312 1030 11349 exclusion phecode
261.2 Vitamin B-complex deficiencies Endocrine/metabolic 1.04 0.963 – 1.13 0.299 646 7125 exclusion phecode
261.4 Vitamin D deficiency Endocrine/metabolic 0.959 0.864 – 1.06 0.429 387 4256 exclusion phecode
261.41 Rickets or osteomalacia Endocrine/metabolic 1.09 0.854 – 1.38 0.5 71 738 exclusion phecode
262 Mineral deficiency NEC Endocrine/metabolic 0.982 0.856 – 1.13 0.792 216 2262 exclusion phecode
269 Proteinuria Endocrine/metabolic 1.03 0.913 – 1.17 0.604 278 3150 exclusion phecode
270
Disorders of protein plasma/amino-acid
Disorders of protein plasma/amino-acid transport and metabolism
 Endocrine/metabolic 0.971 0.857 – 1.1 0.647 265 2832 exclusion phecode
270.3 Disorders of plasma protein metabolism Endocrine/metabolic 0.944 0.827 – 1.08 0.39 232 2426 exclusion phecode
270.32 Paraproteinemia Endocrine/metabolic 0.944 0.806 – 1.11 0.475 164 1769 exclusion phecode
270.33 Amyloidosis Endocrine/metabolic 1.06 0.876 – 1.29 0.533 104 1061 exclusion phecode
270.35 Macroglobulinemia Endocrine/metabolic 0.926 0.723 – 1.19 0.542 67 646 exclusion phecode
271
Disorders of carbohydrate transport and
Disorders of carbohydrate transport and metabolism
 Endocrine/metabolic 1.08 0.904 – 1.29 0.392 130 1523 exclusion phecode
271.3
Intestinal disaccharidase deficiencies and
Intestinal disaccharidase deficiencies and disaccharide malabsorption
 Endocrine/metabolic 1.02 0.849 – 1.23 0.807 116 1326 exclusion phecode
272 Disorders of lipoid metabolism Endocrine/metabolic 1.02 1.01 – 1.03 0.000697 28950 224168 exclusion phecode
272.1 Hyperlipidemia Endocrine/metabolic 1.02 1.01 – 1.03 0.000678 28885 223940 exclusion phecode
272.11 Hypercholesterolemia Endocrine/metabolic 1.02 1.01 – 1.03 0.00111 26890 217030 exclusion phecode
272.12 Hyperglyceridemia Endocrine/metabolic 1.08 0.804 – 1.45 0.606 47 554 exclusion phecode
272.13 Mixed hyperlipidemia Endocrine/metabolic 0.994 0.829 – 1.19 0.945 120 1555 exclusion phecode
272.9 Unspecified disorder of lipoid metabolism Endocrine/metabolic 1.01 0.861 – 1.19 0.896 161 1985 exclusion phecode
274 Gout and other crystal arthropathies Endocrine/metabolic 1 0.965 – 1.04 0.979 3155 34506 exclusion phecode
274.1 Gout Endocrine/metabolic 0.995 0.957 – 1.04 0.81 2649 29328 exclusion phecode
274.11 Gouty arthropathy Endocrine/metabolic 0.932 0.75 – 1.16 0.522 94 1039 exclusion phecode
274.2 Crystal arthropathies Endocrine/metabolic 1.03 0.949 – 1.13 0.452 556 5758 exclusion phecode
274.21 Chondrocalcinosis Endocrine/metabolic 1.03 0.941 – 1.13 0.522 513 5241 exclusion phecode
275 Disorders of mineral metabolism Endocrine/metabolic 0.966 0.921 – 1.01 0.149 1840 19677 exclusion phecode
275.1 Disorders of iron metabolism Hematopoietic 0.929 0.854 – 1.01 0.0867 577 6082 exclusion phecode
275.3 Disorders of magnesium metabolism Endocrine/metabolic 0.99 0.881 – 1.11 0.865 308 3509 exclusion phecode
275.5 Disorders of calcium/phosphorus metabolism Endocrine/metabolic 0.982 0.922 – 1.05 0.582 1055 11243 exclusion phecode
275.53 Disorders of phosphorus metabolism Endocrine/metabolic 1.04 0.883 – 1.23 0.618 151 1592 exclusion phecode
276
Disorders of fluid, electrolyte, and acid-base
Disorders of fluid, electrolyte, and acid-base balance
 Endocrine/metabolic 0.989 0.963 – 1.02 0.402 6025 68192 exclusion phecode
276.1 Electrolyte imbalance Endocrine/metabolic 1 0.965 – 1.04 0.992 3363 38240 exclusion phecode
276.11 Hyperosmolality and/or hypernatremia Endocrine/metabolic 0.925 0.796 – 1.07 0.31 186 2236 exclusion phecode
276.12 Hyposmolality and/or hyponatremia Endocrine/metabolic 0.997 0.947 – 1.05 0.918 1580 17053 exclusion phecode
276.13 Hyperpotassemia Endocrine/metabolic 0.978 0.902 – 1.06 0.584 644 9010 exclusion phecode
276.14 Hypopotassemia Endocrine/metabolic 1.04 0.979 – 1.1 0.219 1250 13379 exclusion phecode
276.4 Acid-base balance disorder Endocrine/metabolic 1.05 0.978 – 1.12 0.183 906 10866 exclusion phecode
276.41 Acidosis Endocrine/metabolic 1.02 0.949 – 1.1 0.585 813 9862 exclusion phecode
276.42 Alkalosis Endocrine/metabolic 1.16 0.945 – 1.43 0.153 101 1053 exclusion phecode
276.5 Hypovolemia Endocrine/metabolic 0.951 0.911 – 0.991 0.0178 2355 26504 exclusion phecode
276.6 Fluid overload Endocrine/metabolic 0.963 0.862 – 1.08 0.504 338 4228 exclusion phecode
276.8 Polydipsia Endocrine/metabolic 1.02 0.838 – 1.25 0.833 100 1224 exclusion phecode
277 Other disorders of metabolism Endocrine/metabolic 0.932 0.866 – 1 0.0592 800 8467 exclusion phecode
277.4 Disorders of bilirubin excretion Endocrine/metabolic 1.06 0.949 – 1.19 0.289 331 3378 exclusion phecode
277.5 Other disorders of lipoid metabolism Endocrine/metabolic 1.09 0.93 – 1.27 0.297 176 2132 exclusion phecode
277.51 Lipoprotein disorders Endocrine/metabolic 1.16 0.825 – 1.64 0.387 38 483 exclusion phecode
278 Overweight, obesity and other hyperalimentation Endocrine/metabolic 0.953 0.932 – 0.974 2.04e-05 8569 102682 exclusion phecode
278.1 Obesity Endocrine/metabolic 0.951 0.93 – 0.973 1.18e-05 8433 101134 exclusion phecode
278.3 Localized adiposity Endocrine/metabolic 1.14 0.896 – 1.44 0.291 75 802 exclusion phecode
278.4 Abnormal weight gain Endocrine/metabolic 0.975 0.735 – 1.29 0.861 52 627 exclusion phecode
279 Disorders involving the immune mechanism Endocrine/metabolic 1.01 0.889 – 1.16 0.836 233 2364 exclusion phecode
279.1 Immunity deficiency Endocrine/metabolic 1.04 0.901 – 1.2 0.586 194 1984 exclusion phecode
279.11 Deficiency of humoral immunity Endocrine/metabolic 0.957 0.802 – 1.14 0.625 131 1313 exclusion phecode
279.7 Other immunological findings Endocrine/metabolic 0.914 0.798 – 1.05 0.191 227 2290 exclusion phecode
280 Iron deficiency anemias Hematopoietic 1 0.978 – 1.03 0.806 6465 72172 exclusion phecode
280.1
Iron deficiency anemias, unspecified or not due
Iron deficiency anemias, unspecified or not due to blood loss
 Hematopoietic 1.01 0.981 – 1.03 0.629 6180 69311 exclusion phecode
280.2
Iron deficiency anemia secondary to blood loss
Iron deficiency anemia secondary to blood loss (chronic)
 Hematopoietic 0.979 0.885 – 1.08 0.673 422 4338 exclusion phecode
281 Other deficiency anemia Hematopoietic 0.968 0.905 – 1.04 0.351 932 10541 exclusion phecode
281.1 Megaloblastic anemia Hematopoietic 0.972 0.908 – 1.04 0.429 893 10104 exclusion phecode
281.11 Pernicious anemia Hematopoietic 0.983 0.905 – 1.07 0.686 618 7120 exclusion phecode
281.12 Other vitamin B12 deficiency anemia Hematopoietic 1.17 0.989 – 1.37 0.0672 149 1678 exclusion phecode
281.13 Folate-deficiency anemia Hematopoietic 0.76 0.643 – 0.897 0.0012 161 1725 exclusion phecode
281.9 Deficiency anemias Hematopoietic 1.02 0.753 – 1.38 0.893 46 514 exclusion phecode
282 Hereditary hemolytic anemias Hematopoietic 1.06 0.892 – 1.25 0.522 133 1422 exclusion phecode
282.8 Other hemoglobinopathies Hematopoietic 1.24 0.953 – 1.62 0.108 51 531 exclusion phecode
282.9 Other hereditary hemolytic anemias Hematopoietic 0.98 0.782 – 1.23 0.863 72 809 exclusion phecode
283 Acquired hemolytic anemias Hematopoietic 0.913 0.759 – 1.1 0.339 117 1290 exclusion phecode
283.1 Autoimmune hemolytic anemias Hematopoietic 0.929 0.748 – 1.15 0.506 89 996 exclusion phecode
284 Aplastic anemia Hematopoietic 0.972 0.874 – 1.08 0.595 379 4117 exclusion phecode
285 Other anemias Hematopoietic 0.987 0.967 – 1.01 0.203 10456 114585 exclusion phecode
285.1 Acute posthemorrhagic anemia Hematopoietic 0.993 0.876 – 1.13 0.91 253 2590 exclusion phecode
285.2 Anemia of chronic disease Hematopoietic 0.99 0.909 – 1.08 0.826 573 6568 exclusion phecode
285.22 Anemia in neoplastic disease Hematopoietic 0.981 0.883 – 1.09 0.718 381 3904 exclusion phecode
286 Coagulation defects Hematopoietic 0.987 0.919 – 1.06 0.726 825 8736 exclusion phecode
286.1 Congenital coagulation defects Hematopoietic 1.01 0.918 – 1.12 0.796 416 4369 exclusion phecode
286.11 Von willebrand's disease Hematopoietic 1 0.819 – 1.23 0.968 91 918 exclusion phecode
286.12
Congenital deficiency of other clotting factors
Congenital deficiency of other clotting factors (including factor VII)
 Hematopoietic 1.01 0.894 – 1.15 0.84 261 2795 exclusion phecode
286.13 Congenital factor VIII disorder Hematopoietic 1.34 1 – 1.8 0.0482 55 597 exclusion phecode
286.5
Hemorrhagic disorder due to intrinsic
Hemorrhagic disorder due to intrinsic circulating anticoagulants
 Hematopoietic 0.969 0.752 – 1.25 0.81 72 797 exclusion phecode
286.7 Other and unspecified coagulation defects Hematopoietic 0.945 0.846 – 1.06 0.319 346 3660 exclusion phecode
287 Purpura and other hemorrhagic conditions Hematopoietic 0.992 0.94 – 1.05 0.774 1469 15512 exclusion phecode
287.1 Spontaneous ecchymoses Hematopoietic 0.847 0.697 – 1.03 0.0954 111 1211 exclusion phecode
287.2 Allergic purpura Hematopoietic 0.847 0.625 – 1.15 0.281 45 486 exclusion phecode
287.3 Thrombocytopenia Hematopoietic 0.979 0.926 – 1.03 0.453 1383 14596 exclusion phecode
287.31 Primary thrombocytopenia Hematopoietic 1.02 0.913 – 1.13 0.782 374 3961 exclusion phecode
287.32 Secondary thrombocytopenia Hematopoietic 0.872 0.686 – 1.11 0.263 65 710 exclusion phecode
288 Diseases of white blood cells Hematopoietic 0.981 0.948 – 1.02 0.282 3503 35525 exclusion phecode
288.1 Decreased white blood cell count Hematopoietic 0.983 0.946 – 1.02 0.361 2964 29932 exclusion phecode
288.11 Neutropenia Hematopoietic 0.983 0.947 – 1.02 0.376 2971 30014 exclusion phecode
288.3 Eosinophilia Hematopoietic 0.891 0.684 – 1.16 0.39 62 663 exclusion phecode
289 Other diseases of blood and blood-forming organs Hematopoietic 0.952 0.885 – 1.03 0.195 774 8112 exclusion phecode
289.3
Personal history of diseases of blood and
Personal history of diseases of blood and blood-forming organs
 Hematopoietic 0.894 0.788 – 1.01 0.0818 259 2760 exclusion phecode
289.4 Lymphadenitis Hematopoietic 1 0.961 – 1.05 0.89 2355 24586 exclusion phecode
289.5 Diseases of spleen Hematopoietic 1 0.908 – 1.1 0.979 434 4831 exclusion phecode
289.8 Polycythemia, secondary Hematopoietic 0.969 0.852 – 1.1 0.633 254 2705 exclusion phecode
289.9 Abnormality of red blood cells Hematopoietic 0.897 0.713 – 1.13 0.352 76 842 exclusion phecode
290
Delirium dementia and amnestic and other
Delirium dementia and amnestic and other cognitive disorders
 Mental Disorders 0.945 0.898 – 0.994 0.0285 1641 17903 exclusion phecode
290.1 Dementias Mental Disorders 0.942 0.878 – 1.01 0.095 857 9276 exclusion phecode
290.11 Alzheimer's disease Mental Disorders 0.894 0.805 – 0.994 0.0382 386 3981 exclusion phecode
290.16 Vascular dementia Mental Disorders 0.838 0.711 – 0.988 0.0355 152 1848 exclusion phecode
290.2 Delirium due to conditions classified elsewhere Mental Disorders 0.945 0.865 – 1.03 0.208 539 6035 exclusion phecode
290.3
Other persistent mental disorders due to
Other persistent mental disorders due to conditions classified elsewhere
 Mental Disorders 1.01 0.79 – 1.3 0.928 66 689 exclusion phecode
291
Other specified nonpsychotic and/or transient
Other specified nonpsychotic and/or transient mental disorders
 Mental Disorders 0.878 0.813 – 0.948 0.000874 722 7929 exclusion phecode
291.1
Transient mental disorders due to conditions
Transient mental disorders due to conditions classified elsewhere
 Mental Disorders 0.802 0.662 – 0.971 0.0236 113 1266 exclusion phecode
291.4
Specific nonpsychotic mental disorders due to
Specific nonpsychotic mental disorders due to brain damage
 Mental Disorders 0.908 0.799 – 1.03 0.14 252 2680 exclusion phecode
291.8 Alteration of consciousness Mental Disorders 0.902 0.81 – 1 0.0601 373 4141 exclusion phecode
292 Neurological disorders Mental Disorders 0.959 0.928 – 0.991 0.0115 3987 43204 exclusion phecode
292.1 Aphasia/speech disturbance Mental Disorders 0.991 0.936 – 1.05 0.756 1287 14150 exclusion phecode
292.2 Mild cognitive impairment Mental Disorders 0.88 0.75 – 1.03 0.12 159 1770 exclusion phecode
292.3 Memory loss Mental Disorders 0.972 0.897 – 1.05 0.487 644 6520 exclusion phecode
292.4 Altered mental status Mental Disorders 0.95 0.906 – 0.997 0.0373 1820 20305 exclusion phecode
292.6 Hallucinations Mental Disorders 0.952 0.839 – 1.08 0.446 269 2892 exclusion phecode
293 Symptoms involving head and neck Mental Disorders 0.948 0.904 – 0.993 0.0253 1873 19540 exclusion phecode
293.1
Swelling, mass, or lump in head and neck
Swelling, mass, or lump in head and neck [Space-occupying lesion, intracranial NOS]
 Mental Disorders 1.05 0.976 – 1.13 0.193 831 8486 exclusion phecode
295 Schizophrenia and other psychotic disorders Mental Disorders 0.92 0.852 – 0.994 0.0336 730 8042 exclusion phecode
295.1 Schizophrenia Mental Disorders 0.902 0.822 – 0.99 0.0302 495 5507 exclusion phecode
295.2 Paranoid disorders Mental Disorders 1.02 0.867 – 1.2 0.807 152 1690 exclusion phecode
295.3 Psychosis Mental Disorders 0.922 0.78 – 1.09 0.346 155 1622 exclusion phecode
296 Mood disorders Mental Disorders 0.976 0.958 – 0.996 0.0164 11154 118283 exclusion phecode
296.1 Bipolar Mental Disorders 0.935 0.874 – 1 0.0488 949 10113 exclusion phecode
296.2 Depression Mental Disorders 0.979 0.959 – 0.998 0.0348 10575 112246 exclusion phecode
296.22 Major depressive disorder Mental Disorders 0.981 0.875 – 1.1 0.748 317 3450 exclusion phecode
297.2 Suicide or self-inflicted injury Mental Disorders 0.969 0.859 – 1.09 0.603 276 2948 exclusion phecode
300 Anxiety disorders Mental Disorders 0.984 0.959 – 1.01 0.215 6285 65322 exclusion phecode
300.1 Anxiety disorder Mental Disorders 0.984 0.958 – 1.01 0.232 5813 60361 exclusion phecode
300.11 Generalized anxiety disorder Mental Disorders 1.06 0.897 – 1.26 0.488 137 1422 exclusion phecode
300.12 Agorophobia, social phobia, and panic disorder Mental Disorders 0.99 0.914 – 1.07 0.813 650 6752 exclusion phecode
300.13 Phobia Mental Disorders 0.97 0.88 – 1.07 0.53 453 4783 exclusion phecode
300.3 Obsessive-compulsive disorders Mental Disorders 0.92 0.769 – 1.1 0.362 131 1352 exclusion phecode
300.4 Dysthymic disorder Mental Disorders 1.16 0.882 – 1.52 0.289 47 498 exclusion phecode
300.8 Acute reaction to stress Mental Disorders 1.05 0.872 – 1.27 0.589 112 1186 exclusion phecode
300.9 Posttraumatic stress disorder Mental Disorders 0.95 0.779 – 1.16 0.61 102 1082 exclusion phecode
301 Personality disorders Mental Disorders 1.05 0.928 – 1.19 0.445 276 3211 exclusion phecode
301.2 Antisocial/borderline personality disorder Mental Disorders 1.14 0.929 – 1.39 0.216 100 1151 exclusion phecode
302 Sexual and gender identity disorders Mental Disorders 1 0.879 – 1.15 0.947 231 2630 exclusion phecode
303 Psychogenic and somatoform disorders Mental Disorders 0.952 0.863 – 1.05 0.333 437 4460 exclusion phecode
303.3 Psychogenic disorder Mental Disorders 0.926 0.827 – 1.04 0.186 333 3341 exclusion phecode
303.4 Somatoform disorder Mental Disorders 1.06 0.867 – 1.29 0.585 110 1186 exclusion phecode
304 Adjustment reaction Mental Disorders 0.981 0.867 – 1.11 0.755 263 2829 exclusion phecode
305.2 Eating disorder Mental Disorders 1.11 0.886 – 1.4 0.358 80 868 exclusion phecode
306 Other mental disorder Mental Disorders 0.989 0.976 – 1 0.108 24886 217816 exclusion phecode
306.9 Tension headache Mental Disorders 0.992 0.88 – 1.12 0.896 289 3047 exclusion phecode
313 Pervasive developmental disorders Mental Disorders 0.91 0.712 – 1.16 0.448 63 732 exclusion phecode
313.3 Autism Mental Disorders 0.927 0.695 – 1.24 0.609 42 511 exclusion phecode
315 Develomental delays and disorders Mental Disorders 1.03 0.911 – 1.15 0.679 302 3293 exclusion phecode
315.1 Learning disorder Mental Disorders 1.02 0.85 – 1.22 0.83 125 1539 exclusion phecode
315.2 Speech and language disorder Mental Disorders 1.01 0.802 – 1.27 0.933 76 806 exclusion phecode
316 Substance addiction and disorders Mental Disorders 1.01 0.977 – 1.04 0.694 4802 50004 exclusion phecode
316.1 Polyneuropathy due to drugs Mental Disorders 0.993 0.756 – 1.31 0.961 55 568 exclusion phecode
317 Alcohol-related disorders Mental Disorders 1.01 0.994 – 1.03 0.17 11642 119575 exclusion phecode
317.1 Alcoholism Mental Disorders 1.01 0.984 – 1.03 0.552 8145 83748 exclusion phecode
317.11 Alcoholic liver damage Mental Disorders 0.984 0.91 – 1.06 0.676 674 7891 exclusion phecode
318 Tobacco use disorder Mental Disorders 1.01 0.992 – 1.02 0.355 17504 175090 exclusion phecode
320 Meningitis Neurological 0.96 0.868 – 1.06 0.434 413 4228 exclusion phecode
323 Encephalitis Neurological 0.976 0.871 – 1.09 0.674 320 3246 exclusion phecode
323.2 Acute (transverse) myelitis Neurological 1.07 0.836 – 1.37 0.592 69 704 exclusion phecode
324 Other CNS infection and poliomyelitis Neurological 0.957 0.842 – 1.09 0.507 265 2741 exclusion phecode
327 Sleep disorders Neurological 0.966 0.905 – 1.03 0.296 991 10938 exclusion phecode
327.3 Sleep apnea Neurological 0.969 0.937 – 1 0.0729 3577 41582 exclusion phecode
327.4 Insomnia Neurological 1.08 0.916 – 1.27 0.359 147 1575 exclusion phecode
327.41 Organic or persistent insomnia Neurological 1.17 0.976 – 1.4 0.0891 125 1325 exclusion phecode
331 Other cerebral degenerations Neurological 0.943 0.884 – 1.01 0.0769 1005 10696 exclusion phecode
331.1 Hydrocephalus Neurological 0.953 0.865 – 1.05 0.323 464 4760 exclusion phecode
331.9 Cerebral degeneration, unspecified Neurological 0.934 0.838 – 1.04 0.214 356 4011 exclusion phecode
332 Parkinson's disease Neurological 0.934 0.875 – 0.996 0.0366 1036 10429 exclusion phecode
333
Extrapyramidal disease and abnormal movement
Extrapyramidal disease and abnormal movement disorders
 Neurological 0.917 0.852 – 0.987 0.0208 802 8440 exclusion phecode
333.1 Essential tremor Neurological 0.928 0.797 – 1.08 0.335 187 2008 exclusion phecode
333.2 Myoclonus Neurological 1.01 0.816 – 1.25 0.927 86 910 exclusion phecode
333.4 Torsion dystonia Neurological 0.977 0.852 – 1.12 0.74 233 2398 exclusion phecode
334 Degenerative disease of the spinal cord Neurological 0.988 0.94 – 1.04 0.64 1634 17019 exclusion phecode
334.1 Spinocerebellar disease Neurological 1.02 0.836 – 1.23 0.877 107 1105 exclusion phecode
334.2 Anterior horn cell disease Neurological 0.982 0.855 – 1.13 0.797 221 2292 exclusion phecode
335 Multiple sclerosis Neurological 0.83 0.783 – 0.88 4.56e-10 1260 12798 exclusion phecode
337 Disorders of the autonomic nervous system Neurological 1 0.876 – 1.15 0.965 228 2499 exclusion phecode
337.1 Peripheral autonomic neuropathy Neurological 0.873 0.668 – 1.14 0.317 59 669 exclusion phecode
338 Pain Neurological 1.06 0.982 – 1.15 0.132 699 7279 exclusion phecode
338.1 Acute pain Neurological 1.07 0.96 – 1.19 0.22 356 3713 exclusion phecode
338.2 Chronic pain Neurological 1.06 0.945 – 1.18 0.335 349 3627 exclusion phecode
339 Other headache syndromes Neurological 1.01 0.989 – 1.04 0.296 7225 74386 exclusion phecode
340 Migraine Neurological 0.966 0.929 – 1.01 0.0889 2697 27382 exclusion phecode
340.1 Migrain with aura Neurological 0.947 0.819 – 1.1 0.464 200 2024 exclusion phecode
341
Other demyelinating diseases of central nervous
Other demyelinating diseases of central nervous system
 Neurological 0.96 0.837 – 1.1 0.553 234 2434 exclusion phecode
342 Hemiplegia Neurological 0.98 0.925 – 1.04 0.492 1275 14011 exclusion phecode
343 Infantile cerebral palsy Neurological 1.2 1.01 – 1.44 0.0439 132 1366 exclusion phecode
344 Other paralytic syndromes Neurological 1.02 0.935 – 1.11 0.699 590 6208 exclusion phecode
345 Epilepsy, recurrent seizures, convulsions Neurological 0.992 0.963 – 1.02 0.609 4610 47531 exclusion phecode
345.1 Epilepsy Neurological 0.976 0.908 – 1.05 0.516 791 8226 exclusion phecode
345.11 Generalized convulsive epilepsy Neurological 1.07 0.97 – 1.19 0.173 395 4182 exclusion phecode
345.12 Partial epilepsy Neurological 0.896 0.789 – 1.02 0.0883 259 2640 exclusion phecode
345.3 Convulsions Neurological 0.979 0.936 – 1.02 0.363 2042 21119 exclusion phecode
346.1
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of skull and head
 Neurological 1.2 1.01 – 1.43 0.0438 127 1338 exclusion phecode
348 Other conditions of brain Neurological 0.982 0.908 – 1.06 0.66 678 7378 exclusion phecode
348.2 Cerebral edema and compression of brain Neurological 1.08 0.942 – 1.23 0.278 238 2553 exclusion phecode
348.4 Cerebral cysts Neurological 0.858 0.715 – 1.03 0.0988 120 1284 exclusion phecode
348.7 Coma Neurological 1.09 0.975 – 1.22 0.131 330 3373 exclusion phecode
348.8 Encephalopathy, not elsewhere classified Neurological 0.99 0.856 – 1.14 0.889 208 2345 exclusion phecode
348.9 Other conditions of brain, NOS Neurological 0.958 0.858 – 1.07 0.445 346 3702 exclusion phecode
349
Other and unspecified disorders of the nervous
Other and unspecified disorders of the nervous system
 Neurological 0.868 0.771 – 0.978 0.0197 302 3234 exclusion phecode
350 Abnormal movement Neurological 0.956 0.916 – 0.997 0.0368 2322 25008 exclusion phecode
350.1 Abnormal involuntary movements Neurological 0.994 0.925 – 1.07 0.875 799 8332 exclusion phecode
350.2 Abnormality of gait Neurological 0.937 0.886 – 0.991 0.0224 1358 14903 exclusion phecode
350.3 Lack of coordination Neurological 0.919 0.819 – 1.03 0.152 316 3416 exclusion phecode
350.6 Disturbances of sensation of smell and taste Neurological 0.821 0.613 – 1.1 0.188 50 508 exclusion phecode
351 Other peripheral nerve disorders Neurological 1.02 0.996 – 1.04 0.125 11191 118192 exclusion phecode
352 Disorders of other cranial nerves Neurological 0.989 0.933 – 1.05 0.712 1234 12993 exclusion phecode
352.1 Trigeminal nerve disorders [CN5] Neurological 0.934 0.846 – 1.03 0.173 435 4427 exclusion phecode
352.2 Facial nerve disorders [CN7] Neurological 1 0.933 – 1.08 0.895 776 8326 exclusion phecode
353 Nerve root and plexus disorders Neurological 1.01 0.95 – 1.08 0.702 1036 10700 exclusion phecode
353.1 Nerve plexus lesions Neurological 1.12 0.926 – 1.35 0.244 109 1084 exclusion phecode
353.2 Nerve root lesions Neurological 1 0.751 – 1.34 0.984 52 533 exclusion phecode
356 Hereditary and idiopathic peripheral neuropathy Neurological 0.924 0.773 – 1.1 0.383 137 1416 exclusion phecode
357 Inflammatory and toxic neuropathy Neurological 0.993 0.933 – 1.06 0.827 1068 12730 exclusion phecode
358 Myoneural disorders Neurological 0.954 0.821 – 1.11 0.537 190 1980 exclusion phecode
358.1 Myasthenia gravis Neurological 0.957 0.819 – 1.12 0.582 172 1804 exclusion phecode
359 Muscular dystrophies and other myopathies Neurological 0.969 0.874 – 1.07 0.549 400 4400 exclusion phecode
359.1 Muscular dystrophies Neurological 1.01 0.832 – 1.23 0.92 116 1151 exclusion phecode
359.2 Myopathy Neurological 0.971 0.864 – 1.09 0.627 299 3404 exclusion phecode
360 Disorders of the globe Sense Organs 1.04 0.922 – 1.17 0.541 312 3184 exclusion phecode
360.2 Progressive myopia Sense Organs 1.05 0.92 – 1.2 0.463 235 2374 exclusion phecode
361 Retinal detachments and defects Sense Organs 1.03 0.996 – 1.07 0.0776 3031 30390 exclusion phecode
361.1 Retinal detachment with retinal defect Sense Organs 1.06 1.01 – 1.13 0.0302 1306 13014 exclusion phecode
361.2 Retinoschisis and retinal cysts Sense Organs 1 0.773 – 1.3 0.98 60 639 exclusion phecode
362 Other retinal disorders Sense Organs 0.98 0.946 – 1.02 0.283 3251 35990 exclusion phecode
362.2
Degeneration of macula and posterior pole of
Degeneration of macula and posterior pole of retina
 Sense Organs 0.955 0.911 – 1 0.0595 1902 20471 exclusion phecode
362.29 Macular degeneration (senile) of retina NOS Sense Organs 0.956 0.912 – 1 0.0626 1900 20441 exclusion phecode
362.3 Other nondiabetic retinopathy Sense Organs 1.06 0.888 – 1.26 0.52 127 1516 exclusion phecode
362.31 Separation of retinal layers Sense Organs 1.01 0.816 – 1.24 0.95 92 926 exclusion phecode
362.4 Retinal vascular changes and abnomalities Sense Organs 0.973 0.9 – 1.05 0.492 700 7915 exclusion phecode
362.6 Peripheral retinal degenerations Sense Organs 1.01 0.858 – 1.18 0.935 166 1712 exclusion phecode
362.7 Hereditary retinal dystrophies Sense Organs 0.987 0.783 – 1.24 0.91 79 773 exclusion phecode
362.8 Retinal hemorrhage/ischemia Sense Organs 1.02 0.838 – 1.25 0.831 102 1090 exclusion phecode
363
Chorioretinal inflammations, scars, and other
Chorioretinal inflammations, scars, and other disorders of choroid
 Sense Organs 0.945 0.798 – 1.12 0.514 150 1614 exclusion phecode
363.3 Chorioretinal scars Sense Organs 1.01 0.769 – 1.33 0.943 53 661 exclusion phecode
364 Corneal opacity and other disorders of cornea Sense Organs 0.929 0.853 – 1.01 0.0878 587 6070 exclusion phecode
364.1 Corneal opacity Sense Organs 1.08 0.867 – 1.34 0.494 81 847 exclusion phecode
364.2 Corneal edema Sense Organs 1.11 0.863 – 1.42 0.424 71 741 exclusion phecode
364.4 Corneal degenerations Sense Organs 1.1 0.941 – 1.29 0.232 173 1891 exclusion phecode
364.41 Keratoconus Sense Organs 0.941 0.749 – 1.18 0.598 81 824 exclusion phecode
364.5 Corneal dystrophy Sense Organs 0.833 0.717 – 0.966 0.0158 198 1990 exclusion phecode
364.9 Cornea replaced by transplant Sense Organs 0.838 0.674 – 1.04 0.111 93 939 exclusion phecode
365 Glaucoma Sense Organs 0.995 0.963 – 1.03 0.745 3986 41133 exclusion phecode
365.1 Open-angle glaucoma Sense Organs 1.04 0.97 – 1.11 0.291 938 9624 exclusion phecode
365.11 Primary open angle glaucoma Sense Organs 1.03 0.965 – 1.1 0.371 932 9574 exclusion phecode
365.2 Primary angle-closure glaucoma Sense Organs 0.918 0.846 – 0.996 0.0388 649 6579 exclusion phecode
366 Cataract Sense Organs 0.997 0.981 – 1.01 0.677 17642 158330 exclusion phecode
366.1 Nonsenile Cataract Sense Organs 0.985 0.761 – 1.28 0.909 65 669 exclusion phecode
366.2 Senile cataract Sense Organs 1 0.976 – 1.02 0.992 7293 76693 exclusion phecode
366.3 Traumatic cataract Sense Organs 1.08 0.877 – 1.32 0.479 94 928 exclusion phecode
367
Disorders of refraction and accommodation
Disorders of refraction and accommodation; blindness and low vision
 Sense Organs 1 0.959 – 1.05 0.941 2194 22670 exclusion phecode
367.1 Myopia Sense Organs 1.05 0.986 – 1.11 0.131 1159 11766 exclusion phecode
367.2 Astigmatism Sense Organs 0.915 0.779 – 1.07 0.273 178 1793 exclusion phecode
367.8 Hypermetropia Sense Organs 0.865 0.754 – 0.991 0.0365 241 2395 exclusion phecode
367.9 Blindness and low vision Sense Organs 0.969 0.892 – 1.05 0.445 616 6764 exclusion phecode
368 Visual disturbances Sense Organs 1.01 0.97 – 1.05 0.639 2668 27947 exclusion phecode
368.1 Amblyopia Sense Organs 0.987 0.898 – 1.08 0.788 465 4962 exclusion phecode
368.2 Diplopia and disorders of binocular vision Sense Organs 1.02 0.946 – 1.11 0.562 658 6893 exclusion phecode
368.3 Anisometropia Sense Organs 1.05 0.882 – 1.25 0.589 145 1440 exclusion phecode
368.4 Visual field defects Sense Organs 0.973 0.86 – 1.1 0.656 288 3118 exclusion phecode
368.9 Subjective visual disturbances Sense Organs 1.04 0.956 – 1.14 0.338 559 5794 exclusion phecode
369 Infection of the eye Sense Organs 0.896 0.818 – 0.982 0.0183 508 5221 exclusion phecode
369.2 Eye infection, viral Sense Organs 0.854 0.701 – 1.04 0.116 117 1175 exclusion phecode
369.5 Conjunctivitis, infectious Sense Organs 0.889 0.77 – 1.03 0.109 194 2013 exclusion phecode
370 Keratitis Sense Organs 1.02 0.896 – 1.16 0.747 255 2702 exclusion phecode
370.1 Corneal ulcer Sense Organs 1.09 0.905 – 1.3 0.375 127 1334 exclusion phecode
371 Inflammation of the eye Sense Organs 1.02 0.983 – 1.06 0.285 2863 28793 exclusion phecode
371.1 Uveitis, noninfectious or NOS Sense Organs 0.979 0.888 – 1.08 0.671 436 4569 exclusion phecode
371.3 Inflammation of eyelids Sense Organs 1.02 0.979 – 1.07 0.31 2236 22240 exclusion phecode
372 Disorders of conjunctiva Sense Organs 0.989 0.915 – 1.07 0.772 707 7142 exclusion phecode
374 Other disorders of eyelids Sense Organs 1.01 0.984 – 1.04 0.389 5212 53459 exclusion phecode
374.1 Ectropion or entropion Sense Organs 0.989 0.926 – 1.06 0.747 951 9879 exclusion phecode
374.3 Ptosis of eyelid Sense Organs 1.04 0.987 – 1.09 0.146 1675 17171 exclusion phecode
375 Disorders of lacrimal system Sense Organs 1 0.956 – 1.05 0.982 2031 20754 exclusion phecode
375.2 Epiphora Sense Organs 1.03 0.955 – 1.1 0.478 826 8400 exclusion phecode
376 Disorders of the orbit Sense Organs 1.03 0.825 – 1.27 0.822 78 807 exclusion phecode
377 Disorders of optic nerve and visual pathways Sense Organs 1.01 0.9 – 1.13 0.876 327 3423 exclusion phecode
377.1 Optic atrophy Sense Organs 1.28 0.947 – 1.72 0.108 50 535 exclusion phecode
377.3 Optic neuritis/neuropathy Sense Organs 0.98 0.807 – 1.19 0.84 115 1197 exclusion phecode
378
Strabismus and other disorders of binocular eye
Strabismus and other disorders of binocular eye movements
 Sense Organs 0.979 0.924 – 1.04 0.458 1294 13387 exclusion phecode
378.1 Strabismus (not specified as paralytic) Sense Organs 0.986 0.919 – 1.06 0.693 854 8629 exclusion phecode
378.2 Nystagmus and other irregular eye movements Sense Organs 0.919 0.793 – 1.06 0.26 188 2006 exclusion phecode
378.5 Paralytic strabismus Sense Organs 0.998 0.876 – 1.14 0.978 243 2625 exclusion phecode
379 Other disorders of eye Sense Organs 1.01 0.971 – 1.04 0.719 3229 34624 exclusion phecode
379.2 Disorders of vitreous body Sense Organs 1.04 0.979 – 1.1 0.203 1155 12781 exclusion phecode
379.3 Aphakia and other disorders of lens Sense Organs 1.03 0.974 – 1.08 0.341 1597 16868 exclusion phecode
379.4 Anomalies of pupillary function Sense Organs 1.23 0.954 – 1.58 0.112 69 668 exclusion phecode
379.5 Disorders of iris and ciliary body Sense Organs 0.965 0.867 – 1.07 0.511 357 3776 exclusion phecode
379.9 Pain, swelling or discharge of eye Sense Organs 1.01 0.855 – 1.19 0.917 150 1609 exclusion phecode
380 Disorders of external ear Sense Organs 1.01 0.926 – 1.1 0.842 581 6004 exclusion phecode
380.1 Otitis externa Sense Organs 1.05 0.956 – 1.16 0.305 439 4850 exclusion phecode
380.4 Impacted cerumen Sense Organs 1.03 0.924 – 1.15 0.572 332 3387 exclusion phecode
381 Otitis media and Eustachian tube disorders Sense Organs 1.02 0.973 – 1.07 0.421 1970 20237 exclusion phecode
381.1 Otitis media Sense Organs 1.04 0.992 – 1.1 0.101 1609 16620 exclusion phecode
381.11 Suppurative and unspecified otitis media Sense Organs 1.08 1 – 1.16 0.0391 781 8014 exclusion phecode
381.2 Eustachian tube disorders Sense Organs 0.948 0.817 – 1.1 0.479 185 1831 exclusion phecode
381.3 Mastoiditis & related conditions Sense Organs 1.03 0.875 – 1.22 0.699 152 1613 exclusion phecode
381.9 Otorrhea Sense Organs 0.962 0.845 – 1.1 0.558 254 2647 exclusion phecode
382 Otalgia Sense Organs 0.966 0.857 – 1.09 0.571 286 2916 exclusion phecode
383 Otosclerosis Sense Organs 0.962 0.855 – 1.08 0.518 299 2952 exclusion phecode
384 Other disorders of tympanic membrane Sense Organs 1.03 0.968 – 1.09 0.382 1212 12284 exclusion phecode
384.4 Perforation of tympanic membrane Sense Organs 1.05 0.98 – 1.12 0.171 975 9877 exclusion phecode
385 Other disorders of middle ear and mastoid Sense Organs 1.03 0.951 – 1.11 0.506 727 7369 exclusion phecode
385.3 Cholesteatoma Sense Organs 1.04 0.955 – 1.13 0.364 562 5687 exclusion phecode
385.5
Tympanosclerosis and middle ear disease related
Tympanosclerosis and middle ear disease related to otitis media
 Sense Organs 0.944 0.821 – 1.08 0.411 225 2279 exclusion phecode
386
Vertiginous syndromes and other disorders of
Vertiginous syndromes and other disorders of vestibular system
 Sense Organs 0.982 0.934 – 1.03 0.495 1614 16424 exclusion phecode
386.1 Meniere's disease Sense Organs 0.987 0.904 – 1.08 0.763 544 5454 exclusion phecode
386.2 Peripheral or central vertigo Sense Organs 0.907 0.812 – 1.01 0.0843 344 3533 exclusion phecode
386.3 Labyrinthitis Sense Organs 1.05 0.974 – 1.14 0.198 708 7253 exclusion phecode
386.9
Dizziness and giddiness (Light-headedness and
Dizziness and giddiness (Light-headedness and vertigo)
 Sense Organs 0.983 0.952 – 1.01 0.288 4162 43123 exclusion phecode
388 Other disorders of ear Sense Organs 0.976 0.84 – 1.13 0.745 186 1909 exclusion phecode
389 Hearing loss Sense Organs 1.01 0.981 – 1.05 0.418 3771 39261 exclusion phecode
389.1 Sensorineural hearing loss Sense Organs 1.04 0.938 – 1.15 0.472 408 4262 exclusion phecode
389.2 Conductive hearing loss Sense Organs 0.977 0.884 – 1.08 0.654 416 4232 exclusion phecode
389.4 Tinnitus Sense Organs 1.03 0.94 – 1.14 0.495 479 4815 exclusion phecode
394 Rheumatic disease of the heart valves Circulatory System 0.979 0.949 – 1.01 0.186 4358 45542 exclusion phecode
394.2 Mitral valve disease Circulatory System 0.987 0.949 – 1.03 0.52 2682 27877 exclusion phecode
394.3 Aortic valve disease Circulatory System 0.996 0.937 – 1.06 0.904 1134 11851 exclusion phecode
394.7 Disease of tricuspid valve Circulatory System 0.976 0.912 – 1.04 0.471 929 9798 exclusion phecode
395 Heart valve disorders Circulatory System 0.998 0.965 – 1.03 0.914 3742 39314 exclusion phecode
395.1 Nonrheumatic mitral valve disorders Circulatory System 0.985 0.947 – 1.03 0.468 2588 26939 exclusion phecode
395.2 Nonrheumatic aortic valve disorders Circulatory System 1.01 0.883 – 1.16 0.881 229 2553 exclusion phecode
395.3 Nonrheumatic tricuspid valve disorders Circulatory System 1.05 0.847 – 1.3 0.667 89 963 exclusion phecode
395.4 Nonrheumatic pulmonary valve disorders Circulatory System 1.05 0.846 – 1.3 0.662 85 899 exclusion phecode
395.6 Heart valve replaced Circulatory System 1.02 0.961 – 1.08 0.551 1308 13910 exclusion phecode
396 Abnormal heart sounds Circulatory System 1.01 0.942 – 1.08 0.839 955 9935 exclusion phecode
401 Hypertension Circulatory System 1.01 1 – 1.02 0.00476 63455 258352 exclusion phecode
401.1 Essential hypertension Circulatory System 1.01 1 – 1.02 0.00406 63258 258135 exclusion phecode
401.2 Hypertensive heart and/or renal disease Circulatory System 1 0.946 – 1.06 0.997 1356 18130 exclusion phecode
401.21 Hypertensive heart disease Circulatory System 0.891 0.791 – 1 0.0576 287 3498 exclusion phecode
401.22 Hypertensive chronic kidney disease Circulatory System 1.03 0.964 – 1.09 0.427 1072 14761 exclusion phecode
401.3 Other hypertensive complications Circulatory System 0.982 0.814 – 1.19 0.853 121 1384 exclusion phecode
402
Elevated blood pressure reading without
Elevated blood pressure reading without diagnosis of hypertension
 Circulatory System 1.04 0.982 – 1.1 0.184 1324 14232 exclusion phecode
411 Ischemic Heart Disease Circulatory System 1.01 0.996 – 1.02 0.189 26474 199521 exclusion phecode
411.1 Unstable angina (intermediate coronary syndrome) Circulatory System 1.01 0.975 – 1.04 0.712 4203 48355 exclusion phecode
411.2 Myocardial infarction Circulatory System 1.01 0.986 – 1.03 0.528 10031 105611 exclusion phecode
411.3 Angina pectoris Circulatory System 1.01 0.987 – 1.02 0.578 13082 135305 exclusion phecode
411.4 Coronary atherosclerosis Circulatory System 1.01 0.994 – 1.03 0.236 17076 145560 exclusion phecode
411.41 Aneurysm and dissection of heart Circulatory System 0.983 0.907 – 1.07 0.679 654 6607 exclusion phecode
411.8
Other chronic ischemic heart disease
Other chronic ischemic heart disease, unspecified
 Circulatory System 0.998 0.98 – 1.02 0.837 12341 123757 exclusion phecode
411.9
Other acute and subacute forms of ischemic
Other acute and subacute forms of ischemic heart disease
 Circulatory System 0.963 0.904 – 1.03 0.249 1039 11418 exclusion phecode
414 Other forms of chronic heart disease Circulatory System 1.02 0.969 – 1.08 0.426 1503 17064 exclusion phecode
414.2 ASCVD Circulatory System 0.817 0.619 – 1.08 0.153 56 673 exclusion phecode
415 Pulmonary heart disease Circulatory System 0.986 0.954 – 1.02 0.382 4049 41907 exclusion phecode
415.11 Pulmonary embolism and infarction, acute Circulatory System 0.842 0.658 – 1.08 0.171 70 698 exclusion phecode
415.2 Chronic pulmonary heart disease Circulatory System 0.991 0.904 – 1.09 0.84 502 5580 exclusion phecode
415.21 Primary pulmonary hypertension Circulatory System 1 0.899 – 1.11 0.996 372 4175 exclusion phecode
416 Cardiomegaly Circulatory System 0.982 0.941 – 1.03 0.409 2238 24840 exclusion phecode
418 Nonspecific chest pain Circulatory System 0.999 0.986 – 1.01 0.892 25725 255784 exclusion phecode
418.1 Precordial pain Circulatory System 1.03 0.99 – 1.07 0.154 3162 33658 exclusion phecode
420 Carditis Circulatory System 0.917 0.874 – 0.961 0.000333 1865 19658 exclusion phecode
420.1 Myocarditis Circulatory System 0.974 0.802 – 1.18 0.789 121 1184 exclusion phecode
420.2 Pericarditis Circulatory System 0.906 0.854 – 0.961 0.00103 1199 12513 exclusion phecode
420.21 Acute pericarditis Circulatory System 0.917 0.793 – 1.06 0.24 200 2095 exclusion phecode
420.22 Chronic pericarditis Circulatory System 0.974 0.795 – 1.19 0.795 102 1038 exclusion phecode
420.3 Endocarditis Circulatory System 0.962 0.886 – 1.04 0.351 621 6684 exclusion phecode
425 Cardiomyopathy Circulatory System 1.01 0.95 – 1.08 0.735 1106 11797 exclusion phecode
425.1 Primary/intrinsic cardiomyopathies Circulatory System 1.03 0.966 – 1.1 0.373 1076 11476 exclusion phecode
425.11 Hypertrophic obstructive cardiomyopathy Circulatory System 0.959 0.791 – 1.16 0.666 123 1239 exclusion phecode
425.12 Other hypertrophic cardiomyopathy Circulatory System 0.873 0.739 – 1.03 0.11 153 1515 exclusion phecode
425.8 Other cardiomyopathy Circulatory System 0.718 0.535 – 0.964 0.0277 53 557 exclusion phecode
426 Cardiac conduction disorders Circulatory System 0.99 0.964 – 1.02 0.45 5951 64423 exclusion phecode
426.2 Atrioventricular [AV] block Circulatory System 0.956 0.91 – 1 0.0675 1783 19598 exclusion phecode
426.21 First degree AV block Circulatory System 0.971 0.904 – 1.04 0.413 824 9130 exclusion phecode
426.23 Second degree AV block Circulatory System 0.981 0.885 – 1.09 0.707 387 4169 exclusion phecode
426.24 Atrioventricular block, complete Circulatory System 0.961 0.876 – 1.05 0.406 491 5429 exclusion phecode
426.25 Other heart block Circulatory System 0.848 0.701 – 1.03 0.0906 121 1215 exclusion phecode
426.3 Bundle branch block Circulatory System 1.01 0.971 – 1.05 0.644 2874 31064 exclusion phecode
426.31 Right bundle branch block Circulatory System 0.982 0.928 – 1.04 0.541 1303 13843 exclusion phecode
426.32 Left bundle branch block Circulatory System 1.03 0.978 – 1.09 0.259 1487 16322 exclusion phecode
426.4 Anomalous atrioventricular excitation Circulatory System 0.907 0.79 – 1.04 0.163 224 2201 exclusion phecode
426.8 Other cardiac conduction disorders Circulatory System 0.961 0.739 – 1.25 0.77 55 564 exclusion phecode
426.9 Cardiac pacemaker/device in situ Circulatory System 0.995 0.951 – 1.04 0.843 2065 23036 exclusion phecode
426.91 Cardiac pacemaker in situ Circulatory System 0.996 0.95 – 1.04 0.864 1901 21148 exclusion phecode
427 Cardiac dysrhythmias Circulatory System 0.983 0.969 – 0.997 0.0145 21632 193998 exclusion phecode
427.1 Paroxysmal tachycardia, unspecified Circulatory System 1.02 0.978 – 1.06 0.4 2884 30138 exclusion phecode
427.11 Paroxysmal supraventricular tachycardia Circulatory System 1.01 0.966 – 1.06 0.648 2122 22187 exclusion phecode
427.12 Paroxysmal ventricular tachycardia Circulatory System 1.07 0.993 – 1.14 0.078 828 8689 exclusion phecode
427.2 Atrial fibrillation and flutter Circulatory System 0.981 0.963 – 0.999 0.0387 12898 124582 exclusion phecode
427.3 Other specified cardiac dysrhythmias Circulatory System 1 0.966 – 1.04 0.88 2910 30189 exclusion phecode
427.4 Cardiac arrest and ventricular fibrillation Circulatory System 0.961 0.902 – 1.02 0.225 1038 11070 exclusion phecode
427.41 Ventricular fibrillation and flutter Circulatory System 0.947 0.842 – 1.06 0.36 306 3215 exclusion phecode
427.42 Cardiac arrest Circulatory System 0.958 0.893 – 1.03 0.224 859 9182 exclusion phecode
427.5 Arrhythmia (cardiac) NOS Circulatory System 0.96 0.895 – 1.03 0.252 847 8931 exclusion phecode
427.6 Premature beats Circulatory System 0.998 0.91 – 1.09 0.964 495 5046 exclusion phecode
427.61 Supraventricular premature beats Circulatory System 0.966 0.796 – 1.17 0.725 110 1092 exclusion phecode
427.7 Tachycardia NOS Circulatory System 0.967 0.922 – 1.01 0.157 1922 20648 exclusion phecode
427.8 Sinoatrial node dysfunction (Bradycardia) Circulatory System 1 0.902 – 1.12 0.944 372 3768 exclusion phecode
427.9 Palpitations Circulatory System 0.983 0.95 – 1.02 0.323 3540 36229 exclusion phecode
428 Congestive heart failure; nonhypertensive Circulatory System 0.969 0.94 – 0.999 0.0447 4440 51854 exclusion phecode
428.1 Congestive heart failure (CHF) NOS Circulatory System 0.978 0.928 – 1.03 0.406 1530 19540 exclusion phecode
428.2 Heart failure NOS Circulatory System 0.968 0.935 – 1 0.0613 3573 41209 exclusion phecode
429
Ill-defined descriptions and complications of
Ill-defined descriptions and complications of heart disease
 Circulatory System 1.04 0.956 – 1.12 0.388 644 6769 exclusion phecode
429.1 Heart transplant/surgery Circulatory System 1.17 0.877 – 1.56 0.286 50 593 exclusion phecode
429.2 Abnormal function study of cardiovascular system Circulatory System 1.02 0.928 – 1.12 0.692 467 4932 exclusion phecode
429.3 Symptoms involving cardiovascular system Circulatory System 1.08 0.929 – 1.26 0.318 178 1875 exclusion phecode
430 Intracranial hemorrhage Circulatory System 1.01 0.964 – 1.06 0.616 1728 17643 exclusion phecode
430.1 Subarachnoid hemorrhage Circulatory System 0.981 0.913 – 1.05 0.609 792 7897 exclusion phecode
430.2 Intracerebral hemorrhage Circulatory System 1.04 0.965 – 1.13 0.286 682 7126 exclusion phecode
430.3 Subdural hemorrhage Circulatory System 1.02 0.895 – 1.16 0.758 245 2472 exclusion phecode
433 Cerebrovascular disease Circulatory System 1.01 0.984 – 1.03 0.56 7542 81511 exclusion phecode
433.1 Occlusion and stenosis of precerebral arteries Circulatory System 1.02 0.956 – 1.09 0.564 1002 10895 exclusion phecode
433.12 Cerebral atherosclerosis Circulatory System 1.04 0.905 – 1.2 0.561 198 2083 exclusion phecode
433.2 Occlusion of cerebral arteries Circulatory System 0.992 0.958 – 1.03 0.641 3595 39337 exclusion phecode
433.21
Cerebral artery occlusion, with cerebral
Cerebral artery occlusion, with cerebral infarction
 Circulatory System 1.02 0.966 – 1.08 0.467 1398 15620 exclusion phecode
433.3 Cerebral ischemia Circulatory System 0.986 0.946 – 1.03 0.504 2491 26988 exclusion phecode
433.31 Transient cerebral ischemia Circulatory System 0.988 0.942 – 1.04 0.605 1841 19872 exclusion phecode
433.5 Cerebral aneurysm Circulatory System 1.09 0.985 – 1.21 0.0929 375 3726 exclusion phecode
433.8 Late effects of cerebrovascular disease Circulatory System 0.992 0.931 – 1.06 0.797 1067 11931 exclusion phecode
440 Atherosclerosis Circulatory System 1.04 0.976 – 1.11 0.231 1071 12769 exclusion phecode
440.1 Atherosclerosis of renal artery Circulatory System 1.13 0.917 – 1.39 0.255 93 1050 exclusion phecode
440.2 Atherosclerosis of the extremities Circulatory System 0.985 0.905 – 1.07 0.727 585 7417 exclusion phecode
440.9 Atherosclerosis of aorta Circulatory System 1.05 0.918 – 1.19 0.497 240 2683 exclusion phecode
441 Vascular insufficiency of intestine Circulatory System 0.981 0.899 – 1.07 0.664 547 5781 exclusion phecode
441.1 Acute vascular insufficiency of intestine Circulatory System 0.934 0.82 – 1.06 0.302 251 2662 exclusion phecode
442 Other aneurysm Circulatory System 0.985 0.937 – 1.03 0.542 1708 17490 exclusion phecode
442.1 Aortic aneurysm Circulatory System 0.984 0.93 – 1.04 0.582 1319 13408 exclusion phecode
442.11 Abdominal aortic aneurysm Circulatory System 0.993 0.924 – 1.07 0.847 820 8506 exclusion phecode
442.2 Aneurysm of iliac artery Circulatory System 0.955 0.778 – 1.17 0.659 94 917 exclusion phecode
442.3 Aneurysm of artery of lower extremity Circulatory System 1.07 0.906 – 1.27 0.421 146 1570 exclusion phecode
442.4 Arterial dissection Circulatory System 0.966 0.724 – 1.29 0.814 51 514 exclusion phecode
442.8 Aneurysm of other specified artery Circulatory System 0.953 0.82 – 1.11 0.531 185 1913 exclusion phecode
443 Peripheral vascular disease Circulatory System 1 0.966 – 1.04 0.878 3006 36571 exclusion phecode
443.1 Raynaud's syndrome Circulatory System 0.977 0.918 – 1.04 0.467 1086 10870 exclusion phecode
443.7
Peripheral angiopathy in diseases classified
Peripheral angiopathy in diseases classified elsewhere
 Circulatory System 0.949 0.705 – 1.28 0.729 41 3589 exclusion phecode
443.8 Other specified peripheral vascular diseases Circulatory System 1 0.965 – 1.04 0.898 2974 34365 exclusion phecode
443.9 Peripheral vascular disease, unspecified Circulatory System 1.02 0.975 – 1.07 0.379 1922 23831 exclusion phecode
444 Arterial embolism and thrombosis Circulatory System 1.02 0.947 – 1.1 0.583 718 8610 exclusion phecode
444.1
Arterial embolism and thrombosis of lower
Arterial embolism and thrombosis of lower extremity artery
 Circulatory System 1.13 1.02 – 1.25 0.0152 406 5146 exclusion phecode
446 Polyarteritis nodosa and allied conditions Circulatory System 1.04 0.969 – 1.13 0.256 741 7678 exclusion phecode
446.4 Wegener's granulomatosis Circulatory System 1.17 0.998 – 1.36 0.053 172 1723 exclusion phecode
446.5 Giant cell arteritis Circulatory System 1.01 0.911 – 1.13 0.789 357 3634 exclusion phecode
446.9 Arteritis NOS Circulatory System 0.991 0.861 – 1.14 0.904 210 2248 exclusion phecode
447 Other disorders of arteries and arterioles Circulatory System 1.01 0.952 – 1.08 0.677 1057 12339 exclusion phecode
447.1 Stricture of artery Circulatory System 1.08 0.996 – 1.17 0.0632 662 8034 exclusion phecode
448 Disease of capillaries Circulatory System 1.01 0.846 – 1.21 0.893 126 1350 exclusion phecode
450 Noninfectious disorders of lymphatic channels Circulatory System 0.985 0.906 – 1.07 0.718 622 6653 exclusion phecode
451 Phlebitis and thrombophlebitis Circulatory System 1.01 0.975 – 1.04 0.619 3583 37235 exclusion phecode
451.2
Phlebitis and thrombophlebitis of lower
Phlebitis and thrombophlebitis of lower extremities
 Circulatory System 1 0.968 – 1.04 0.85 3333 34673 exclusion phecode
452 Other venous embolism and thrombosis Circulatory System 0.913 0.834 – 0.999 0.0464 504 5325 exclusion phecode
454 Varicose veins Circulatory System 0.978 0.959 – 0.998 0.0294 10645 106214 exclusion phecode
454.1 Varicose veins of lower extremity Circulatory System 0.972 0.953 – 0.991 0.00423 10991 109279 exclusion phecode
454.11 Varicose veins of lower extremity, symptomtic Circulatory System 0.875 0.802 – 0.956 0.00302 559 5934 exclusion phecode
455 Hemorrhoids Circulatory System 1 0.989 – 1.02 0.647 21963 221341 exclusion phecode
456 Chronic venous insufficiency [CVI] Circulatory System 0.9 0.764 – 1.06 0.205 157 1731 exclusion phecode
457
Encounter for long-term (current) use of
Encounter for long-term (current) use of anticoagulants, antithrombotics, aspirin
 Circulatory System 0.98 0.784 – 1.22 0.858 93 886 exclusion phecode
458 Hypotension Circulatory System 0.996 0.968 – 1.03 0.803 5060 54226 exclusion phecode
458.1 Orthostatic hypotension Circulatory System 1.01 0.95 – 1.07 0.743 1127 12541 exclusion phecode
458.2 Iatrogenic hypotension Circulatory System 1.02 0.887 – 1.17 0.78 203 2184 exclusion phecode
458.9 Hypotension NOS Circulatory System 1 0.965 – 1.04 0.951 3061 32860 exclusion phecode
459 Other disorders of circulatory system Circulatory System 0.988 0.971 – 1.01 0.174 14299 150891 exclusion phecode
459.1 Hemorrhage NOS Circulatory System 0.959 0.795 – 1.16 0.66 127 1317 exclusion phecode
459.9 Circulatory disease NEC Circulatory System 0.99 0.973 – 1.01 0.232 14148 149588 exclusion phecode
464 Acute sinusitis Respiratory 1.22 1.05 – 1.42 0.0102 179 1865 exclusion phecode
465
Acute upper respiratory infections of multiple
Acute upper respiratory infections of multiple or unspecified sites
 Respiratory 1.03 0.985 – 1.08 0.196 2081 21652 exclusion phecode
465.2 Acute pharyngitis Respiratory 1.01 0.942 – 1.09 0.711 767 7913 exclusion phecode
465.4 Acute laryngitis and tracheitis Respiratory 0.963 0.814 – 1.14 0.658 155 1573 exclusion phecode
470 Septal Deviations/Turbinate Hypertrophy Respiratory 0.998 0.968 – 1.03 0.908 4369 44045 exclusion phecode
471 Nasal polyps Respiratory 1.07 1.03 – 1.11 0.000691 3095 30910 exclusion phecode
472 Chronic pharyngitis and nasopharyngitis Respiratory 1.01 0.945 – 1.08 0.736 904 9064 exclusion phecode
473 Diseases of the larynx and vocal cords Respiratory 1.01 0.966 – 1.05 0.706 2338 23998 exclusion phecode
473.1 Chronic laryngitis Respiratory 0.859 0.693 – 1.07 0.168 92 976 exclusion phecode
473.3 Paralysis/spasm of vocal cords or larynx Respiratory 0.973 0.851 – 1.11 0.688 239 2490 exclusion phecode
473.4 Voice disturbance Respiratory 0.983 0.92 – 1.05 0.621 975 10113 exclusion phecode
474 Acute and chronic tonsillitis Respiratory 1.01 0.961 – 1.06 0.692 1679 16979 exclusion phecode
474.1 Acute tonsillitis Respiratory 1.04 0.948 – 1.13 0.431 513 5287 exclusion phecode
474.2 Chronic tonsillitis and adenoiditis Respiratory 1.03 0.965 – 1.09 0.413 1070 10754 exclusion phecode
475 Chronic sinusitis Respiratory 1.02 0.978 – 1.06 0.374 2423 24482 exclusion phecode
476 Allergic rhinitis Respiratory 0.969 0.908 – 1.03 0.341 994 10060 exclusion phecode
477 Epistaxis or throat hemorrhage Respiratory 0.977 0.936 – 1.02 0.308 2190 22832 exclusion phecode
478 Throat pain Respiratory 0.906 0.812 – 1.01 0.079 351 3573 exclusion phecode
479 Other upper respiratory disease Respiratory 0.999 0.966 – 1.03 0.948 3780 38512 exclusion phecode
480 Pneumonia Respiratory 0.966 0.946 – 0.987 0.00186 9060 96649 exclusion phecode
480.1 Bacterial pneumonia Respiratory 0.953 0.928 – 0.979 0.000516 5822 62035 exclusion phecode
480.11 Pneumococcal pneumonia Respiratory 0.95 0.923 – 0.978 0.000444 5175 54956 exclusion phecode
480.12 Pseudomonal pneumonia Respiratory 1.08 0.859 – 1.35 0.513 84 854 exclusion phecode
480.2 Viral pneumonia Respiratory 1.17 0.909 – 1.5 0.225 67 677 exclusion phecode
480.3 Pneumonia due to fungus (mycoses) Respiratory 1.05 0.854 – 1.29 0.636 91 921 exclusion phecode
480.5 Bronchopneumonia and lung abscess Respiratory 1.01 0.93 – 1.09 0.883 686 7400 exclusion phecode
481 Influenza Respiratory 1.05 0.938 – 1.18 0.382 310 3102 exclusion phecode
483 Acute bronchitis and bronchiolitis Respiratory 1.21 1.04 – 1.42 0.0156 170 1806 exclusion phecode
495 Asthma Respiratory 1.03 1.01 – 1.04 0.000223 23495 237944 exclusion phecode
495.2 Asthma with exacerbation Respiratory 1 0.872 – 1.15 0.997 218 2384 exclusion phecode
496 Chronic airway obstruction Respiratory 1 0.979 – 1.02 0.989 9132 94825 exclusion phecode
496.1 Emphysema Respiratory 1 0.953 – 1.06 0.879 1565 16169 exclusion phecode
496.2 Chronic bronchitis Respiratory 0.993 0.953 – 1.03 0.722 2544 27371 exclusion phecode
496.21 Obstructive chronic bronchitis Respiratory 0.997 0.956 – 1.04 0.901 2340 25095 exclusion phecode
496.3 Bronchiectasis Respiratory 0.984 0.936 – 1.03 0.51 1737 17711 exclusion phecode
497 Bronchitis Respiratory 0.947 0.868 – 1.03 0.215 566 5926 exclusion phecode
500 Lung disease due to external agents Respiratory 0.867 0.777 – 0.967 0.0106 360 3774 exclusion phecode
500.1 Extrinsic allergic alveolitis Respiratory 0.934 0.735 – 1.19 0.579 72 730 exclusion phecode
500.2 Pneumoconiosis Respiratory 0.839 0.725 – 0.97 0.0175 210 2186 exclusion phecode
501 Pneumonitis due to inhalation of food or vomitus Respiratory 0.983 0.901 – 1.07 0.695 570 6095 exclusion phecode
502 Postinflammatory pulmonary fibrosis Respiratory 0.988 0.92 – 1.06 0.738 803 8485 exclusion phecode
503 Pulmonary congestion and hypostasis Respiratory 0.955 0.86 – 1.06 0.388 387 4746 exclusion phecode
504 Other alveolar and parietoalveolar pneumonopathy Respiratory 0.967 0.856 – 1.09 0.595 287 3065 exclusion phecode
505 Other pulmonary inflamation or edema Respiratory 1.02 0.776 – 1.34 0.887 57 567 exclusion phecode
506 Empyema and pneumothorax Respiratory 0.987 0.926 – 1.05 0.697 1040 10616 exclusion phecode
507 Pleurisy; pleural effusion Respiratory 0.961 0.935 – 0.987 0.00398 5653 60009 exclusion phecode
508
Pulmonary collapse; interstitial and
Pulmonary collapse; interstitial and compensatory emphysema
 Respiratory 0.951 0.906 – 0.998 0.0415 1778 18719 exclusion phecode
509 Respiratory failure, insufficiency, arrest Respiratory 1.01 0.968 – 1.06 0.599 2189 24263 exclusion phecode
509.1 Respiratory failure Respiratory 1.01 0.966 – 1.07 0.563 1740 19285 exclusion phecode
509.2 Respiratory insufficiency Respiratory 1 0.953 – 1.06 0.867 1529 16876 exclusion phecode
509.5 Respiratory arrest Respiratory 0.909 0.759 – 1.09 0.297 127 1341 exclusion phecode
509.8
Dependence on respirator [Ventilator] or
Dependence on respirator [Ventilator] or supplemental oxygen
 Respiratory 1.03 0.918 – 1.15 0.623 316 3606 exclusion phecode
510 Other diseases of lung Respiratory 1.02 0.941 – 1.1 0.665 678 7063 exclusion phecode
512 Other symptoms of respiratory system Respiratory 0.992 0.969 – 1.01 0.472 7972 85020 exclusion phecode
512.1 Wheezing Respiratory 0.973 0.837 – 1.13 0.72 191 2053 exclusion phecode
512.2 Painful respiration Respiratory 1.07 0.93 – 1.24 0.332 199 1962 exclusion phecode
512.7 Shortness of breath Respiratory 0.99 0.962 – 1.02 0.476 5100 55012 exclusion phecode
512.8 Cough Respiratory 0.976 0.938 – 1.02 0.245 2587 26966 exclusion phecode
512.9 Other dyspnea Respiratory 1 0.93 – 1.08 0.995 787 8567 exclusion phecode
513 Respiratory abnormalities Respiratory 1.06 0.971 – 1.16 0.193 522 5717 exclusion phecode
513.3 Hypoventilation Respiratory 0.838 0.638 – 1.1 0.202 57 776 exclusion phecode
513.4 Hyperventilation Respiratory 1.14 1.01 – 1.3 0.0385 252 2633 exclusion phecode
513.8 Disorders of diaphragm Respiratory 1.11 0.931 – 1.32 0.249 134 1427 exclusion phecode
514 Abnormal findings examination of lungs Respiratory 1.01 0.968 – 1.06 0.62 2225 22934 exclusion phecode
516 Abnormal sputum Respiratory 0.976 0.93 – 1.02 0.306 1893 19892 exclusion phecode
516.1 Hemoptysis Respiratory 0.976 0.93 – 1.02 0.327 1838 19364 exclusion phecode
519
Other diseases of respiratory system, not
Other diseases of respiratory system, not elsewhere classified
 Respiratory 0.989 0.967 – 1.01 0.361 8205 87976 exclusion phecode
519.2 Respiratory complications Respiratory 0.99 0.878 – 1.12 0.865 287 3066 exclusion phecode
519.8 Other diseases of respiratory system, NEC Respiratory 0.99 0.967 – 1.01 0.398 7743 83171 exclusion phecode
519.9
Symptoms involving respiratory system and other
Symptoms involving respiratory system and other chest symptoms
 Respiratory 0.974 0.86 – 1.1 0.674 285 2872 exclusion phecode
520 Disorders of tooth development Digestive 0.967 0.923 – 1.01 0.165 1937 19484 exclusion phecode
520.1 Hereditary disturbances in tooth structure Digestive 0.961 0.715 – 1.29 0.79 50 512 exclusion phecode
520.2 Disturbances in tooth eruption Digestive 0.97 0.929 – 1.01 0.171 2249 22566 exclusion phecode
521 Diseases of hard tissues of teeth Digestive 1.02 0.978 – 1.06 0.399 2715 28722 exclusion phecode
521.1 Dental caries Digestive 1.02 0.982 – 1.06 0.285 2724 28828 exclusion phecode
522 Diseases of pulp and periapical tissues Digestive 1.01 0.965 – 1.07 0.563 1665 16910 exclusion phecode
522.5 Periapical abscess Digestive 1.03 0.968 – 1.1 0.346 1089 11171 exclusion phecode
523 Gingival and periodontal diseases Digestive 0.983 0.933 – 1.03 0.505 1574 16027 exclusion phecode
523.1 Gingivitis Digestive 1.18 0.96 – 1.45 0.115 109 1073 exclusion phecode
523.3 Periodontitis (acute or chronic) Digestive 1.01 0.947 – 1.07 0.836 1110 11138 exclusion phecode
523.31 Acute periodontitis Digestive 0.995 0.917 – 1.08 0.899 636 6402 exclusion phecode
523.32 Chronic periodontitis Digestive 1.01 0.925 – 1.1 0.83 534 5310 exclusion phecode
524 Dentofacial anomalies, including malocclusion Digestive 0.964 0.858 – 1.08 0.536 319 3167 exclusion phecode
524.3 Anomalies of tooth position/malocclusion Digestive 0.996 0.883 – 1.12 0.945 294 2909 exclusion phecode
525
Other diseases of the teeth and supporting
Other diseases of the teeth and supporting structures
 Digestive 0.991 0.951 – 1.03 0.675 2453 25252 exclusion phecode
525.2 Atrophy of edentulous alveolar ridge Digestive 0.841 0.654 – 1.08 0.177 68 675 exclusion phecode
526 Diseases of the jaws Digestive 1.01 0.945 – 1.09 0.704 877 8840 exclusion phecode
526.1 Cysts of the jaws Digestive 0.97 0.861 – 1.09 0.612 306 3125 exclusion phecode
526.3 Anomalies of jaw size/symmetry Digestive 0.903 0.694 – 1.17 0.447 59 588 exclusion phecode
526.4 Temporomandibular joint disorders Digestive 1.11 0.971 – 1.27 0.123 232 2317 exclusion phecode
526.41 Temporomandibular joint disorder, unspecified Digestive 1.11 0.972 – 1.28 0.12 225 2252 exclusion phecode
526.5 Inflammatory conditions of jaw Digestive 1.03 0.845 – 1.26 0.745 101 1048 exclusion phecode
526.9 Jaw disease NOS Digestive 0.947 0.823 – 1.09 0.442 221 2187 exclusion phecode
527 Diseases of the salivary glands Digestive 1.02 0.936 – 1.1 0.716 631 6570 exclusion phecode
527.1 Hypertrophy of salivary gland Digestive 1.23 0.977 – 1.55 0.0785 77 790 exclusion phecode
527.2 Sialoadenitis Digestive 1.02 0.912 – 1.14 0.73 331 3475 exclusion phecode
527.7 Disturbance of salivary secretion Digestive 0.906 0.687 – 1.2 0.487 58 585 exclusion phecode
527.8 Other specified diseases of the salivary glands Digestive 0.928 0.767 – 1.12 0.438 114 1130 exclusion phecode
528
Diseases of the oral soft tissues, excluding
Diseases of the oral soft tissues, excluding lesions specific for gingiva and tongue
 Digestive 1.02 0.987 – 1.06 0.226 3592 36647 exclusion phecode
528.1 Stomatitis and mucositis Digestive 0.956 0.865 – 1.06 0.384 426 4417 exclusion phecode
528.11 Stomatitis and mucositis (ulcerative) Digestive 0.948 0.849 – 1.06 0.342 354 3675 exclusion phecode
528.12 Oral aphthae Digestive 0.98 0.776 – 1.24 0.868 76 795 exclusion phecode
528.3 Cellulitis and abscess of oral soft tissues Digestive 0.962 0.82 – 1.13 0.632 161 1693 exclusion phecode
528.4 Cysts of oral soft tissues Digestive 0.959 0.787 – 1.17 0.678 119 1152 exclusion phecode
528.41 Cyst of the salivary gland Digestive 1.08 0.861 – 1.35 0.513 92 889 exclusion phecode
528.5 Diseases of lips Digestive 1.02 0.945 – 1.11 0.564 648 6442 exclusion phecode
528.6 Leukoplakia of oral mucosa Digestive 1.06 0.94 – 1.2 0.342 282 2915 exclusion phecode
528.7 Sialolithiasis Digestive 1.07 0.947 – 1.2 0.287 288 2949 exclusion phecode
529 Diseases and other conditions of the tongue Digestive 0.971 0.914 – 1.03 0.35 1127 11615 exclusion phecode
529.1 Glossitis Digestive 1.01 0.888 – 1.14 0.902 269 2816 exclusion phecode
530 Diseases of esophagus Digestive 0.997 0.986 – 1.01 0.648 30729 264360 exclusion phecode
530.1 Esophagitis, GERD and related diseases Digestive 0.998 0.986 – 1.01 0.775 28746 257848 exclusion phecode
530.11 GERD Digestive 1 0.988 – 1.02 0.723 20933 213547 exclusion phecode
530.12 Ulcer of esophagus Digestive 0.991 0.962 – 1.02 0.568 4732 48651 exclusion phecode
530.14 Reflux esophagitis Digestive 0.994 0.974 – 1.02 0.591 9652 98531 exclusion phecode
530.2 Esophageal bleeding (varices/hemorrhage) Digestive 1.01 0.955 – 1.06 0.794 1449 15782 exclusion phecode
530.3 Stricture and stenosis of esophagus Digestive 0.975 0.927 – 1.02 0.312 1716 17450 exclusion phecode
530.5 Disorders of esophageal motility Digestive 0.943 0.867 – 1.03 0.178 591 6027 exclusion phecode
530.6 Diverticulum of esophagus, acquired Digestive 0.863 0.724 – 1.03 0.101 141 1432 exclusion phecode
530.7 Gastroesophageal laceration-hemorrhage syndrome Digestive 1.04 0.93 – 1.17 0.461 307 3240 exclusion phecode
530.9 Heartburn Digestive 1 0.954 – 1.05 0.993 1963 19749 exclusion phecode
531 Peptic ulcer (excl. esophageal) Digestive 1 0.978 – 1.03 0.776 6334 66470 exclusion phecode
531.1 Hemorrhage from gastrointestinal ulcer Digestive 0.994 0.912 – 1.08 0.888 576 5886 exclusion phecode
531.2 Gastric ulcer Digestive 1.02 0.989 – 1.06 0.183 3616 38404 exclusion phecode
531.3 Duodenal ulcer Digestive 1.01 0.975 – 1.06 0.47 2710 27967 exclusion phecode
531.4 Peptic ulcer, site unspecified Digestive 0.937 0.844 – 1.04 0.223 378 3960 exclusion phecode
532 Dysphagia Digestive 0.977 0.951 – 1 0.0856 5929 60706 exclusion phecode
535 Gastritis and duodenitis Digestive 0.998 0.985 – 1.01 0.761 25512 247401 exclusion phecode
535.1 Acute gastritis Digestive 1.07 1 – 1.14 0.0433 1043 11095 exclusion phecode
535.2 Atrophic gastritis Digestive 1.02 0.909 – 1.14 0.774 332 3460 exclusion phecode
535.6 Duodenitis Digestive 0.986 0.962 – 1.01 0.261 6866 71419 exclusion phecode
535.8 Other specified gastritis Digestive 0.991 0.968 – 1.02 0.461 7303 76187 exclusion phecode
535.9 Gastritis and duodenitis, NOS Digestive 1.12 0.919 – 1.36 0.268 111 1112 exclusion phecode
536.8
Dyspepsia and other specified disorders of
Dyspepsia and other specified disorders of function of stomach
 Digestive 1 0.88 – 1.14 0.985 237 2437 exclusion phecode
537 Other disorders of stomach and duodenum Digestive 0.995 0.958 – 1.03 0.78 3017 31937 exclusion phecode
540 Appendiceal conditions Digestive 1 0.963 – 1.04 0.994 2946 29333 exclusion phecode
540.1 Appendicitis Digestive 0.994 0.956 – 1.03 0.754 2768 27499 exclusion phecode
540.11 Acute appendicitis Digestive 0.993 0.953 – 1.03 0.734 2486 24685 exclusion phecode
550 Abdominal hernia Digestive 1 0.991 – 1.01 0.74 42036 267890 exclusion phecode
550.1 Inguinal hernia Digestive 1.02 1 – 1.04 0.0448 15043 114143 exclusion phecode
550.2 Diaphragmatic hernia Digestive 0.994 0.981 – 1.01 0.403 24303 225693 exclusion phecode
550.3 Femoral hernia Digestive 0.971 0.895 – 1.05 0.475 643 6178 exclusion phecode
550.4 Umbilical hernia Digestive 0.948 0.914 – 0.983 0.00386 3231 34608 exclusion phecode
550.5 Ventral hernia Digestive 0.997 0.961 – 1.03 0.888 3094 32276 exclusion phecode
555
Inflammatory bowel disease and other
Inflammatory bowel disease and other gastroenteritis and colitis
 Digestive 0.967 0.936 – 0.998 0.0391 4110 42198 exclusion phecode
555.1 Regional enteritis Digestive 1.02 0.968 – 1.07 0.474 1615 16508 exclusion phecode
555.2 Ulcerative colitis Digestive 0.945 0.91 – 0.982 0.00383 2925 30119 exclusion phecode
555.21 Ulcerative colitis (chronic) Digestive 0.883 0.804 – 0.969 0.00872 500 5102 exclusion phecode
556 Ulceration of the lower GI tract Digestive 0.997 0.934 – 1.06 0.933 980 10066 exclusion phecode
556.1 Ulceration of intestine Digestive 0.997 0.918 – 1.08 0.936 624 6385 exclusion phecode
557 Intestinal malabsorption (non-celiac) Digestive 1.05 0.928 – 1.19 0.439 269 2867 exclusion phecode
557.1 Celiac disease Digestive 0.976 0.929 – 1.03 0.348 1728 17479 exclusion phecode
558 Noninfectious gastroenteritis Digestive 0.996 0.978 – 1.01 0.62 13933 147608 exclusion phecode
559 Ileostomy status Digestive 0.936 0.888 – 0.987 0.0151 1505 15646 exclusion phecode
560 Intestinal obstruction without mention of hernia Digestive 0.965 0.933 – 0.999 0.0437 3625 37175 exclusion phecode
560.1 Paralytic ileus Digestive 0.974 0.887 – 1.07 0.587 475 4886 exclusion phecode
560.2 Impaction of intestine Digestive 0.922 0.807 – 1.05 0.236 245 2535 exclusion phecode
560.3 Peritoneal or intestinal adhesions Digestive 0.942 0.875 – 1.01 0.114 773 7898 exclusion phecode
560.4 Other intestinal obstruction Digestive 0.971 0.936 – 1.01 0.121 3106 31745 exclusion phecode
561 Symptoms involving digestive system Digestive 0.998 0.981 – 1.02 0.82 14628 150168 exclusion phecode
561.1 Diarrhea Digestive 0.871 0.789 – 0.96 0.00571 442 4407 exclusion phecode
561.2 Flatulence Digestive 1.01 0.963 – 1.07 0.605 1577 16031 exclusion phecode
562 Diverticulosis and diverticulitis Digestive 1 0.986 – 1.01 0.943 24336 200327 exclusion phecode
562.1 Diverticulosis Digestive 0.999 0.986 – 1.01 0.94 24304 200278 exclusion phecode
563 Constipation Digestive 0.998 0.977 – 1.02 0.828 9388 97782 exclusion phecode
564 Functional digestive disorders Digestive 1.01 0.994 – 1.02 0.276 19892 199204 exclusion phecode
564.1 Irritable Bowel Syndrome Digestive 1.03 1 – 1.06 0.0326 5125 52788 exclusion phecode
564.8
Abnormal findings on exam of gastrointestinal
Abnormal findings on exam of gastrointestinal tract/ abdominal area
 Digestive 0.998 0.947 – 1.05 0.948 1506 15594 exclusion phecode
564.9 Personal history of diseases of digestive system Digestive 0.997 0.979 – 1.01 0.71 13876 143160 exclusion phecode
565 Anal and rectal conditions Digestive 1 0.982 – 1.02 0.974 13575 138890 exclusion phecode
565.1 Anal and rectal polyp Digestive 1.01 0.981 – 1.03 0.674 6731 68946 exclusion phecode
567 Peritonitis and retroperitoneal infections Digestive 0.926 0.862 – 0.995 0.0364 807 8736 exclusion phecode
568 Other disorders of peritoneum Digestive 0.995 0.958 – 1.03 0.776 3010 30910 exclusion phecode
568.1
Peritoneal adhesions (postoperative)
Peritoneal adhesions (postoperative) (postinfection)
 Digestive 0.993 0.956 – 1.03 0.738 2863 29370 exclusion phecode
569 Other disorders of intestine Digestive 1.01 0.973 – 1.04 0.707 3781 39469 exclusion phecode
569.1 Toxic gastroenteritis and colitis Digestive 1.11 0.927 – 1.33 0.255 130 1387 exclusion phecode
569.2 Gastrointestinal complications Digestive 0.959 0.871 – 1.06 0.394 452 4552 exclusion phecode
571 Chronic liver disease and cirrhosis Digestive 0.982 0.941 – 1.02 0.404 2298 27875 exclusion phecode
571.5 Other chronic nonalcoholic liver disease Digestive 1.02 0.961 – 1.08 0.565 1276 15957 exclusion phecode
571.51 Cirrhosis of liver without mention of alcohol Digestive 1.13 0.909 – 1.39 0.278 85 1064 exclusion phecode
571.6 Primary biliary cirrhosis Digestive 0.924 0.807 – 1.06 0.254 235 2450 exclusion phecode
571.8
Liver abscess and sequelae of chronic liver
Liver abscess and sequelae of chronic liver disease
 Digestive 0.962 0.893 – 1.04 0.303 752 9194 exclusion phecode
571.81 Portal hypertension Digestive 0.948 0.854 – 1.05 0.307 380 4962 exclusion phecode
572 Ascites (non malignant) Digestive 0.976 0.922 – 1.03 0.392 1327 14521 exclusion phecode
573 Other disorders of liver Digestive 0.944 0.892 – 0.998 0.0413 1341 14109 exclusion phecode
573.2 Liver replaced by transplant Digestive 0.938 0.737 – 1.19 0.602 72 901 exclusion phecode
573.3 Hepatomegaly Digestive 0.989 0.869 – 1.13 0.864 244 2785 exclusion phecode
573.5 Jaundice (not of newborn) Digestive 0.949 0.883 – 1.02 0.16 798 8392 exclusion phecode
573.7 Abnormal results of function study of liver Digestive 1 0.964 – 1.04 0.971 3027 32618 exclusion phecode
573.9 Abnormal serum enzyme levels Digestive 1.04 0.891 – 1.21 0.643 182 1938 exclusion phecode
574 Cholelithiasis and cholecystitis Digestive 1.01 0.99 – 1.02 0.419 14237 148220 exclusion phecode
574.1 Cholelithiasis Digestive 1 0.984 – 1.02 0.772 12362 128746 exclusion phecode
574.11 Cholelithiasis with acute cholecystitis Digestive 1.02 0.962 – 1.08 0.546 1362 14233 exclusion phecode
574.12 Cholelithiasis with other cholecystitis Digestive 0.992 0.963 – 1.02 0.574 4994 51608 exclusion phecode
574.2 Calculus of bile duct Digestive 0.982 0.942 – 1.02 0.405 2397 24744 exclusion phecode
574.3 Cholecystitis without cholelithiasis Digestive 1.05 1 – 1.09 0.0366 2453 26038 exclusion phecode
575 Other biliary tract disease Digestive 0.98 0.947 – 1.01 0.254 3517 36487 exclusion phecode
575.1 Cholangitis Digestive 1 0.91 – 1.11 0.942 439 4584 exclusion phecode
575.2 Obstruction of bile duct Digestive 0.951 0.879 – 1.03 0.216 687 7223 exclusion phecode
575.6 Cholesterolosis of gallbladder Digestive 0.984 0.893 – 1.09 0.751 429 4368 exclusion phecode
575.7 Other disorders of gallbladder Digestive 1.01 0.958 – 1.07 0.614 1296 13362 exclusion phecode
575.8 Other disorders of biliary tract Digestive 0.922 0.863 – 0.986 0.0171 937 9770 exclusion phecode
575.9
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of biliary tract
 Digestive 0.966 0.859 – 1.09 0.563 311 3264 exclusion phecode
577 Diseases of pancreas Digestive 0.989 0.948 – 1.03 0.621 2318 25039 exclusion phecode
577.1 Acute pancreatitis Digestive 0.982 0.935 – 1.03 0.469 1749 18760 exclusion phecode
577.2 Chronic pancreatitis Digestive 1.02 0.922 – 1.13 0.703 402 4821 exclusion phecode
577.3 Cyst and pseudocyst of pancreas Digestive 1.08 0.965 – 1.22 0.172 306 3419 exclusion phecode
578 Gastrointestinal hemorrhage Digestive 0.992 0.977 – 1.01 0.274 19004 194935 exclusion phecode
578.1 Hematemesis Digestive 0.957 0.911 – 1.01 0.0835 1710 18403 exclusion phecode
578.2 Blood in stool Digestive 0.993 0.952 – 1.04 0.745 2348 24635 exclusion phecode
578.8 Hemorrhage of rectum and anus Digestive 0.99 0.972 – 1.01 0.285 12141 123882 exclusion phecode
578.9 Hemorrhage of gastrointestinal tract Digestive 0.991 0.962 – 1.02 0.55 4852 49810 exclusion phecode
579 Other symptoms involving abdomen and pelvis Digestive 0.988 0.934 – 1.04 0.666 1360 14667 exclusion phecode
579.2 Splenomegaly Digestive 0.925 0.826 – 1.04 0.178 332 3963 exclusion phecode
579.8 Nonspecific abnormal findings in stool contents Digestive 0.942 0.893 – 0.994 0.0293 1505 15642 exclusion phecode
580 Nephritis; nephrosis; renal sclerosis Genitourinary 0.94 0.884 – 1 0.0526 1062 14380 exclusion phecode
580.1 Glomerulonephritis Genitourinary 0.953 0.886 – 1.02 0.187 790 9865 exclusion phecode
580.11 Proliferative glomerulonephritis Genitourinary 1 0.782 – 1.28 0.996 65 695 exclusion phecode
580.12 Non-proliferative glomerulonephritis Genitourinary 0.972 0.804 – 1.18 0.77 120 1288 exclusion phecode
580.14 Chronic glomerulonephritis, NOS Genitourinary 0.931 0.859 – 1.01 0.0824 634 8183 exclusion phecode
580.2
Nephrotic syndrome without mention of
Nephrotic syndrome without mention of glomerulonephritis
 Genitourinary 0.926 0.811 – 1.06 0.255 227 4397 exclusion phecode
580.3
Nephritis and nephropathy without mention of
Nephritis and nephropathy without mention of glomerulonephritis
 Genitourinary 1.03 0.89 – 1.19 0.702 204 2328 exclusion phecode
580.32
Nephritis and nephropathy with pathological
Nephritis and nephropathy with pathological lesion
 Genitourinary 1.02 0.887 – 1.18 0.746 207 2397 exclusion phecode
585 Renal failure Genitourinary 0.967 0.941 – 0.994 0.0181 5425 64995 exclusion phecode
585.1 Acute renal failure Genitourinary 0.956 0.923 – 0.99 0.0115 3464 42142 exclusion phecode
585.2 Renal failure NOS Genitourinary 0.959 0.904 – 1.02 0.173 1172 13634 exclusion phecode
585.3 Chronic renal failure [CKD] Genitourinary 0.984 0.939 – 1.03 0.483 1923 24661 exclusion phecode
585.31 Renal dialysis Genitourinary 0.919 0.828 – 1.02 0.117 380 4640 exclusion phecode
586 Other disorders of the kidney and ureters Genitourinary 0.986 0.95 – 1.02 0.466 2972 31547 exclusion phecode
586.1 Anatomical abnormatilies of kidney and ureters Genitourinary 0.914 0.783 – 1.07 0.255 185 1974 exclusion phecode
586.11 Small kidney Genitourinary 0.914 0.774 – 1.08 0.295 157 1701 exclusion phecode
586.2 Cyst of kidney, acquired Genitourinary 0.995 0.936 – 1.06 0.866 1135 11756 exclusion phecode
586.3 Vascular disorders of kidney/hypertrophy Genitourinary 1.01 0.785 – 1.31 0.91 70 747 exclusion phecode
586.4 Stricture/obstruction of ureter Genitourinary 0.997 0.928 – 1.07 0.932 818 8584 exclusion phecode
587 Kidney replaced by transpant Genitourinary 0.915 0.813 – 1.03 0.14 307 3498 exclusion phecode
588 Disorders resulting from impaired renal function Genitourinary 1.16 0.926 – 1.45 0.196 78 923 exclusion phecode
589 Abnormal results of function study of kidney Genitourinary 0.866 0.698 – 1.07 0.191 94 1096 exclusion phecode
590 Pyelonephritis Genitourinary 1.02 0.96 – 1.08 0.531 1180 12664 exclusion phecode
591 Urinary tract infection Genitourinary 0.982 0.963 – 1 0.0699 10956 116943 exclusion phecode
592 Cystitis and urethritis Genitourinary 1.01 0.975 – 1.06 0.479 2703 28064 exclusion phecode
592.1 Cystitis Genitourinary 1.02 0.978 – 1.06 0.378 2647 27483 exclusion phecode
592.11 Acute cystitis Genitourinary 0.84 0.701 – 1.01 0.061 127 1288 exclusion phecode
592.12 Chronic cystitis Genitourinary 0.992 0.922 – 1.07 0.818 809 8385 exclusion phecode
592.13 Chronic interstitial cystitis Genitourinary 1.05 0.921 – 1.2 0.466 234 2359 exclusion phecode
592.2 Urethritis and urethral syndrome Genitourinary 1.13 0.956 – 1.33 0.157 152 1577 exclusion phecode
593 Hematuria Genitourinary 1.01 0.995 – 1.03 0.168 14660 150490 exclusion phecode
594 Urinary calculus Genitourinary 1.01 0.98 – 1.04 0.597 5637 59787 exclusion phecode
594.1 Calculus of kidney Genitourinary 0.985 0.948 – 1.02 0.463 2770 29764 exclusion phecode
594.2 Calculus of lower urinary tract Genitourinary 1.06 0.981 – 1.15 0.142 676 7198 exclusion phecode
594.3 Calculus of ureter Genitourinary 1.01 0.962 – 1.05 0.807 2104 22472 exclusion phecode
594.8 Renal colic Genitourinary 1.01 0.96 – 1.06 0.77 1830 19298 exclusion phecode
595 Hydronephrosis Genitourinary 1.02 0.972 – 1.07 0.394 1708 18144 exclusion phecode
596 Other disorders of bladder Genitourinary 1.01 0.984 – 1.03 0.618 8894 91056 exclusion phecode
596.1 Bladder neck obstruction Genitourinary 0.988 0.941 – 1.04 0.62 1785 18071 exclusion phecode
596.5 Functional disorders of bladder Genitourinary 0.938 0.89 – 0.989 0.0169 1505 15631 exclusion phecode
597 Other disorders of urethra and urinary tract Genitourinary 1.02 0.99 – 1.06 0.163 3558 36701 exclusion phecode
597.1 Urethral stricture (not specified as infectious) Genitourinary 1.03 0.991 – 1.07 0.135 3002 31026 exclusion phecode
597.2 Urinary complications NEC Genitourinary 0.924 0.725 – 1.18 0.523 67 728 exclusion phecode
598 Abnormal findings on examination of urine Genitourinary 1 0.967 – 1.04 0.882 3201 32890 exclusion phecode
598.9
Other nonspecific findings on examination of
Other nonspecific findings on examination of urine
 Genitourinary 0.926 0.82 – 1.05 0.217 270 2848 exclusion phecode
599 Other symptoms/disorders or the urinary system Genitourinary 1 0.984 – 1.02 0.998 16879 174093 exclusion phecode
599.1 Urinary obstruction Genitourinary 0.905 0.761 – 1.08 0.261 141 1543 exclusion phecode
599.2 Retention of urine Genitourinary 1.01 0.985 – 1.04 0.396 6033 62088 exclusion phecode
599.3 Dysuria Genitourinary 0.97 0.911 – 1.03 0.35 1082 11281 exclusion phecode
599.4 Urinary incontinence Genitourinary 0.982 0.96 – 1 0.111 8118 83676 exclusion phecode
599.5 Frequency of urination and polyuria Genitourinary 1 0.967 – 1.04 0.975 3641 37653 exclusion phecode
599.6 Oliguria and anuria Genitourinary 1.04 0.837 – 1.3 0.699 84 989 exclusion phecode
599.8 Other symptoms involving urinary system Genitourinary 1.08 0.827 – 1.41 0.568 60 577 exclusion phecode
599.9 Other abnormality of urination Genitourinary 0.98 0.933 – 1.03 0.432 1726 17873 exclusion phecode
600 Hyperplasia of prostate Genitourinary 1.01 0.988 – 1.03 0.415 9996 80373 exclusion phecode
601 Inflammatory diseases of prostate Genitourinary 1.03 0.982 – 1.08 0.226 1876 19115 exclusion phecode
601.1 Prostatitis Genitourinary 1.03 0.974 – 1.08 0.313 1456 14346 exclusion phecode
601.11 Acute prostatitis Genitourinary 0.977 0.851 – 1.12 0.737 214 2159 exclusion phecode
601.12 Chronic prostatitis Genitourinary 0.994 0.926 – 1.07 0.878 838 8250 exclusion phecode
601.3 Orchitis and epididymitis Genitourinary 0.847 0.647 – 1.11 0.225 55 543 exclusion phecode
601.4 Balanoposthitis Genitourinary 1 0.878 – 1.14 0.974 227 2628 exclusion phecode
601.8
Other inflammatory disorders of male genital
Other inflammatory disorders of male genital organs
 Genitourinary 1.12 0.986 – 1.26 0.0831 259 2786 exclusion phecode
602 Other disorders of prostate Genitourinary 1.08 1.02 – 1.15 0.00788 1216 12179 exclusion phecode
603 Other disorders of testis Genitourinary 0.982 0.937 – 1.03 0.442 1921 19960 exclusion phecode
603.1 Hydrocele Genitourinary 0.998 0.941 – 1.06 0.958 1197 12347 exclusion phecode
604 Disorders of penis Genitourinary 1.01 0.972 – 1.05 0.605 2786 30489 exclusion phecode
604.1 Redundant prepuce and phimosis/BXO Genitourinary 0.992 0.951 – 1.04 0.727 2287 25254 exclusion phecode
605 Erectile dysfunction [ED] Genitourinary 1.01 0.883 – 1.16 0.874 222 2516 exclusion phecode
608 Other disorders of male genital organs Genitourinary 0.942 0.905 – 0.981 0.00388 2616 26196 exclusion phecode
609 Male infertility and abnormal spermatozoa Genitourinary 1.04 0.903 – 1.21 0.566 190 1955 exclusion phecode
609.1 Infertility, male Genitourinary 1.07 0.827 – 1.4 0.59 57 604 exclusion phecode
609.2 Abnormal spermatozoa Genitourinary 1.08 0.919 – 1.26 0.36 149 1527 exclusion phecode
610 Benign mammary dysplasias Genitourinary 0.982 0.941 – 1.02 0.397 2382 23939 exclusion phecode
610.1 Cystic mastopathy Genitourinary 0.962 0.897 – 1.03 0.282 886 8911 exclusion phecode
610.2 Fibroadenosis of breast Genitourinary 1.1 0.981 – 1.24 0.101 293 2939 exclusion phecode
610.3 Fibrosclerosis of breast Genitourinary 0.931 0.825 – 1.05 0.245 292 2908 exclusion phecode
610.4 Benign neoplasm of breast Genitourinary 0.978 0.925 – 1.03 0.438 1341 13391 exclusion phecode
610.8 Other specified benign mammary dysplasias Genitourinary 0.961 0.886 – 1.04 0.34 648 6695 exclusion phecode
611 Abnormal findings on mammogram or breast exam Genitourinary 0.999 0.947 – 1.05 0.964 1509 15151 exclusion phecode
611.1 Abnormal mammogram Genitourinary 1.03 0.772 – 1.37 0.855 56 543 exclusion phecode
611.3 Lump or mass in breast Genitourinary 0.997 0.945 – 1.05 0.924 1458 14671 exclusion phecode
612
Breast conditions, congenital or relating to
Breast conditions, congenital or relating to hormones
 Genitourinary 0.992 0.924 – 1.07 0.823 834 8530 exclusion phecode
612.2 Hypertrophy of breast (Gynecomastia) Genitourinary 0.975 0.906 – 1.05 0.491 792 8135 exclusion phecode
612.3 Congenital anomalies of breast Genitourinary 1.09 0.867 – 1.38 0.452 72 702 exclusion phecode
613 Other nonmalignant breast conditions Genitourinary 0.972 0.922 – 1.02 0.285 1562 15868 exclusion phecode
613.1 Inflammatory disease of breast Genitourinary 1.01 0.933 – 1.09 0.817 681 6902 exclusion phecode
613.5 Mastodynia Genitourinary 0.918 0.715 – 1.18 0.502 71 740 exclusion phecode
613.7 Other signs and symptoms in breast Genitourinary 0.951 0.878 – 1.03 0.224 674 6734 exclusion phecode
613.8 Other specified disorders of breast Genitourinary 1.03 0.914 – 1.15 0.661 308 3153 exclusion phecode
613.9 Breast disorder NOS Genitourinary 0.954 0.827 – 1.1 0.52 195 1993 exclusion phecode
614 Inflammatory diseases of female pelvic organs Genitourinary 1.02 0.992 – 1.05 0.167 5440 55217 exclusion phecode
614.1
Pelvic peritoneal adhesions, female
Pelvic peritoneal adhesions, female (postoperative) (postinfection)
 Genitourinary 1.01 0.964 – 1.05 0.79 2415 24562 exclusion phecode
614.3 Pelvic inflammatory disease (PID) Genitourinary 1.04 0.967 – 1.12 0.282 786 8054 exclusion phecode
614.31 Acute inflammatory pelvic disease Genitourinary 1.05 0.803 – 1.38 0.71 58 589 exclusion phecode
614.32 Chronic inflammatory pelvic disease Genitourinary 1.07 0.965 – 1.19 0.198 401 4085 exclusion phecode
614.33 Pelvic inflammatory disease, NOS Genitourinary 1.03 0.921 – 1.16 0.59 331 3406 exclusion phecode
614.4 Inflammatory diseases of uterus, except cervix Genitourinary 1.21 1.06 – 1.37 0.00407 260 2681 exclusion phecode
614.5
Inflammatory disease of cervix, vagina, and
Inflammatory disease of cervix, vagina, and vulva
 Genitourinary 1.03 0.989 – 1.07 0.146 2489 25106 exclusion phecode
614.51 Cervicitis and endocervicitis Genitourinary 0.979 0.924 – 1.04 0.475 1273 12705 exclusion phecode
614.52 Vaginitis and vulvovaginitis Genitourinary 0.99 0.894 – 1.1 0.843 400 4104 exclusion phecode
614.53 Cyst or abscess of Bartholin's gland Genitourinary 1.03 0.958 – 1.11 0.393 738 7335 exclusion phecode
614.54 Abscess or ulceration of vulva Genitourinary 1.11 0.976 – 1.26 0.112 239 2637 exclusion phecode
615 Endometriosis Genitourinary 1.05 1.02 – 1.09 0.00182 3889 39090 exclusion phecode
617
Disorders secondary to childbirth, surgery
Disorders secondary to childbirth, surgery, trauma
 Genitourinary 1.07 0.946 – 1.21 0.279 282 2913 exclusion phecode
618 Genital prolapse Genitourinary 1 0.983 – 1.02 0.823 11118 112036 exclusion phecode
618.1 Prolapse of vaginal walls Genitourinary 0.989 0.965 – 1.01 0.382 7003 70837 exclusion phecode
618.2 Uterine/Uterovaginal prolapse Genitourinary 1.02 0.986 – 1.04 0.303 5155 51655 exclusion phecode
618.5 Prolapse of vaginal vault after hysterectomy Genitourinary 1.05 0.953 – 1.15 0.343 486 4904 exclusion phecode
618.6 Vaginal enterocele, congenital or acquired Genitourinary 0.958 0.884 – 1.04 0.305 644 6499 exclusion phecode
619 Noninflammatory female genital disorders Genitourinary 1.01 0.984 – 1.03 0.605 8363 84184 exclusion phecode
619.1
Noninflammatory disorders of ovary, fallopian
Noninflammatory disorders of ovary, fallopian tube, and broad ligament
 Genitourinary 0.996 0.922 – 1.08 0.91 693 7033 exclusion phecode
619.2 Disorders of uterus, NEC Genitourinary 1.03 0.995 – 1.07 0.09 3193 32009 exclusion phecode
619.3 Noninflammatory disorders of cervix Genitourinary 0.98 0.942 – 1.02 0.311 2749 27642 exclusion phecode
619.4 Noninflammatory disorders of vagina Genitourinary 0.95 0.903 – 0.999 0.0455 1677 17029 exclusion phecode
619.5 Noninflammatory disorders of vulva and perineum Genitourinary 1.04 0.986 – 1.11 0.143 1300 13027 exclusion phecode
620 Dysplasia of female genital organs Genitourinary 1 0.788 – 1.28 0.974 69 696 exclusion phecode
621 Endometrial hyperplasia Genitourinary 1.07 1.01 – 1.15 0.0266 1039 10848 exclusion phecode
622 Polyp of female genital organs Genitourinary 1.01 0.988 – 1.03 0.442 9968 100916 exclusion phecode
622.1 Polyp of corpus uteri Genitourinary 1.01 0.988 – 1.04 0.313 7440 75629 exclusion phecode
622.2 Mucous polyp of cervix Genitourinary 1.01 0.978 – 1.05 0.448 3310 33101 exclusion phecode
623 Hypertrophy of female genital organs Genitourinary 1.06 1 – 1.13 0.0497 1206 12258 exclusion phecode
624 Symptoms involving female genital tract Genitourinary 1 0.931 – 1.08 0.954 763 7635 exclusion phecode
624.1 Dystrophy of female genital tract Genitourinary 1.11 0.972 – 1.27 0.125 223 2263 exclusion phecode
624.2 Atrophy of female genital tract Genitourinary 0.967 0.874 – 1.07 0.521 424 4232 exclusion phecode
624.9 stress incontinence, female Genitourinary 0.988 0.961 – 1.02 0.404 5523 56453 exclusion phecode
625
Pain and other symptoms associated with female
Pain and other symptoms associated with female genital organs
 Genitourinary 1.01 0.968 – 1.05 0.757 2785 27865 exclusion phecode
625.1 Dyspareunia Genitourinary 0.968 0.911 – 1.03 0.295 1145 11517 exclusion phecode
626
Disorders of menstruation and other abnormal
Disorders of menstruation and other abnormal bleeding from female genital tract
 Genitourinary 1.02 1 – 1.03 0.0465 15528 111487 exclusion phecode
626.1 Irregular menstrual cycle/bleeding Genitourinary 1.02 0.997 – 1.03 0.0929 13545 106593 exclusion phecode
626.11 Absent or infrequent menstruation Genitourinary 0.964 0.792 – 1.17 0.711 104 1065 exclusion phecode
626.12 Excessive or frequent menstruation Genitourinary 1.01 0.987 – 1.03 0.458 9300 88996 exclusion phecode
626.13 Irregular menstrual cycle Genitourinary 1.05 0.997 – 1.1 0.0672 1893 19168 exclusion phecode
626.14 Irregular menstrual bleeding Genitourinary 1.04 1.01 – 1.08 0.0226 3672 36941 exclusion phecode
626.2 Dysmenorrhea Genitourinary 1.01 0.959 – 1.06 0.752 1699 17257 exclusion phecode
626.4 Premenstrual tension syndromes Genitourinary 1.03 0.873 – 1.22 0.726 156 1546 exclusion phecode
626.8 Infertility, female Genitourinary 1.07 1.01 – 1.13 0.0279 1330 13255 exclusion phecode
627 Menopausal and postmenopausal disorders Genitourinary 1 0.984 – 1.03 0.652 9793 99738 exclusion phecode
627.1 Postmenopausal bleeding Genitourinary 1.01 0.989 – 1.03 0.314 8516 86721 exclusion phecode
627.2 Symptomatic menopause Genitourinary 0.942 0.807 – 1.1 0.444 176 1772 exclusion phecode
627.3 Postmenopausal atrophic vaginitis Genitourinary 0.975 0.916 – 1.04 0.429 1065 10660 exclusion phecode
627.4 Premenopausal menorrhagia Genitourinary 0.974 0.864 – 1.1 0.669 289 2989 exclusion phecode
628 Ovarian cyst Genitourinary 1.03 0.994 – 1.06 0.11 4542 45955 exclusion phecode
634 Miscarriage; stillbirth Pregnancy Complications 0.979 0.951 – 1.01 0.168 5105 35607 exclusion phecode
634.1 Missed abortion/Hydatidiform mole Pregnancy Complications 0.952 0.895 – 1.01 0.118 1111 11073 exclusion phecode
634.3 Ectopic pregnancy Pregnancy Complications 0.982 0.874 – 1.1 0.757 324 3241 exclusion phecode
635
Hemorrhage during pregnancy; childbirth and
Hemorrhage during pregnancy; childbirth and postpartum
 Pregnancy Complications 0.946 0.902 – 0.992 0.0217 1922 17014 exclusion phecode
635.2
Antepartum hemorrhage, abruptio placentae, and
Antepartum hemorrhage, abruptio placentae, and placenta previa
 Pregnancy Complications 0.955 0.889 – 1.03 0.211 848 8440 exclusion phecode
635.3 Placenta previa and abruptio placenta Pregnancy Complications 0.929 0.876 – 0.985 0.0138 1234 12059 exclusion phecode
636
Early or threatened labor; hemorrhage in early
Early or threatened labor; hemorrhage in early pregnancy
 Pregnancy Complications 0.999 0.957 – 1.04 0.98 2286 19568 exclusion phecode
636.2 Early onset of delivery Pregnancy Complications 1.05 0.964 – 1.14 0.269 593 6017 exclusion phecode
636.3 Hemorrhage in early pregnancy Pregnancy Complications 0.984 0.924 – 1.05 0.628 1049 10542 exclusion phecode
638 Other high-risk pregnancy Pregnancy Complications 0.985 0.767 – 1.26 0.904 67 686 exclusion phecode
642
Hypertension complicating pregnancy
Hypertension complicating pregnancy, childbirth, and the puerperium
 Pregnancy Complications 1.04 0.978 – 1.11 0.207 1053 10847 exclusion phecode
642.1 Preeclampsia and eclampsia Pregnancy Complications 1.2 1.07 – 1.36 0.00266 289 2990 exclusion phecode
643 Excessive vomiting in pregnancy Pregnancy Complications 0.996 0.863 – 1.15 0.955 203 2106 exclusion phecode
643.1 Hyperemesis gravidarum Pregnancy Complications 1.03 0.867 – 1.22 0.756 145 1496 exclusion phecode
645 Late pregnancy and failed induction Pregnancy Complications 0.951 0.897 – 1.01 0.0967 1221 12220 exclusion phecode
646 Other complications of pregnancy NEC Pregnancy Complications 1.02 0.979 – 1.07 0.305 2148 20439 exclusion phecode
647
Infectious and parasitic complications
Infectious and parasitic complications affecting pregnancy
 Pregnancy Complications 1.35 1.05 – 1.73 0.0184 68 663 exclusion phecode
647.1
Infections of genitourinary tract during
Infections of genitourinary tract during pregnancy
 Pregnancy Complications 1.02 0.897 – 1.15 0.796 268 2698 exclusion phecode
649
Other conditions or status of the mother
Other conditions or status of the mother complicating pregnancy, childbirth, or the puerperium
 Pregnancy Complications 1.02 0.843 – 1.23 0.85 107 1112 exclusion phecode
649.1
Diabetes or abnormal glucose tolerance
Diabetes or abnormal glucose tolerance complicating pregnancy
 Pregnancy Complications 0.914 0.697 – 1.2 0.514 50 1891 exclusion phecode
650 Normal delivery Pregnancy Complications 1.02 0.969 – 1.06 0.514 1892 18558 exclusion phecode
651 Multiple gestation Pregnancy Complications 1.09 0.974 – 1.22 0.136 338 3390 exclusion phecode
652
Malposition and malpresentation of fetus or
Malposition and malpresentation of fetus or obstruction
 Pregnancy Complications 0.982 0.934 – 1.03 0.471 1675 16191 exclusion phecode
653
Problems associated with amniotic cavity and
Problems associated with amniotic cavity and membranes
 Pregnancy Complications 0.948 0.896 – 1 0.0571 1371 13371 exclusion phecode
654
Other and unspecified complications of birth
Other and unspecified complications of birth; puerperium affecting management of mother
 Pregnancy Complications 0.894 0.709 – 1.13 0.345 72 727 exclusion phecode
655
Known or suspected fetal abnormality affecting
Known or suspected fetal abnormality affecting management of mother
 Pregnancy Complications 0.981 0.95 – 1.01 0.262 4192 28851 exclusion phecode
656 Other perinatal conditions of fetus or newborn Pregnancy Complications 0.88 0.723 – 1.07 0.203 105 1051 exclusion phecode
661 Fetal distress and abnormal forces of labor Pregnancy Complications 0.982 0.939 – 1.03 0.426 2210 18007 exclusion phecode
663
Umbilical cord complications during labor and
Umbilical cord complications during labor and delivery
 Pregnancy Complications 1.01 0.919 – 1.1 0.904 517 5194 exclusion phecode
665 Obstetrical/birth trauma Pregnancy Complications 0.988 0.959 – 1.02 0.441 5235 28815 exclusion phecode
669 Complications of labor and delivery NEC Pregnancy Complications 0.979 0.939 – 1.02 0.313 2502 20734 exclusion phecode
671
Venous/cerebrovascular complications embolism
Venous/cerebrovascular complications embolism in pregnancy and the puerperium
 Pregnancy Complications 0.943 0.798 – 1.11 0.487 158 1586 exclusion phecode
674 Other complications of the puerperium NEC Pregnancy Complications 1.07 0.941 – 1.22 0.292 251 2547 exclusion phecode
676
Other disorders of the breast associated with
Other disorders of the breast associated with childbirth and disorders of lactation
 Pregnancy Complications 1.13 0.865 – 1.48 0.369 63 609 exclusion phecode
679 Complications of in utero procedures Dermatologic 0.789 0.588 – 1.06 0.113 51 514 exclusion phecode
681 Superficial cellulitis and abscess Dermatologic 0.973 0.948 – 0.999 0.0416 6104 67994 exclusion phecode
681.1 Cellulitis and abscess of fingers/toes Dermatologic 0.97 0.883 – 1.07 0.525 473 5322 exclusion phecode
681.2 Cellulitis and abscess of face/neck Dermatologic 0.974 0.887 – 1.07 0.571 474 4941 exclusion phecode
681.3 Cellulitis and abscess of arm/hand Dermatologic 0.96 0.931 – 0.99 0.00837 4576 51689 exclusion phecode
681.5 Cellulitis and abscess of leg, except foot Dermatologic 0.964 0.935 – 0.993 0.0172 4581 51745 exclusion phecode
681.6 Cellulitis and abscess of foot, toe Dermatologic 0.962 0.933 – 0.992 0.0122 4541 51336 exclusion phecode
681.7 Cellulitis and abscess of trunk Dermatologic 1.01 0.927 – 1.11 0.784 524 5692 exclusion phecode
686
Other local infections of skin and subcutaneous
Other local infections of skin and subcutaneous tissue
 Dermatologic 0.978 0.921 – 1.04 0.479 1124 12646 exclusion phecode
686.1 Carbuncle and furuncle Dermatologic 0.99 0.945 – 1.04 0.671 1948 21676 exclusion phecode
686.3 Pilonidal cyst Dermatologic 1 0.915 – 1.09 0.984 524 5552 exclusion phecode
686.4 Pyogenic granuloma Dermatologic 1.05 0.937 – 1.17 0.407 328 3429 exclusion phecode
687 Symptoms affecting skin Dermatologic 0.992 0.905 – 1.09 0.872 498 5216 exclusion phecode
687.1 Rash and other nonspecific skin eruption Dermatologic 0.99 0.946 – 1.04 0.685 1945 20296 exclusion phecode
687.2 Localized superficial swelling, mass, or lump Dermatologic 1.02 0.896 – 1.16 0.774 264 2692 exclusion phecode
687.3 Changes in skin texture Dermatologic 0.937 0.771 – 1.14 0.51 103 1007 exclusion phecode
687.4 Disturbance of skin sensation Dermatologic 0.983 0.944 – 1.02 0.385 2637 27337 exclusion phecode
689 Disorder of skin and subcutaneous tissue NOS Dermatologic 1 0.976 – 1.03 0.782 5340 54233 exclusion phecode
690 Erythematosquamous dermatosis Dermatologic 1.02 0.793 – 1.31 0.875 63 652 exclusion phecode
690.1 Seborrheic dermatitis Dermatologic 0.966 0.716 – 1.3 0.821 46 494 exclusion phecode
691 Congenital anomalies of skin Dermatologic 0.97 0.8 – 1.18 0.756 112 1120 exclusion phecode
694 Dyschromia and Vitiligo Dermatologic 1.02 0.952 – 1.09 0.582 924 9323 exclusion phecode
694.1 Vitiligo Dermatologic 1.21 0.92 – 1.6 0.172 52 567 exclusion phecode
694.2 Other dyschromia Dermatologic 1.03 0.957 – 1.11 0.407 748 7415 exclusion phecode
694.3 Vascular disorders of skin Dermatologic 0.817 0.663 – 1.01 0.0594 99 1104 exclusion phecode
695 Erythematous conditions Dermatologic 0.978 0.936 – 1.02 0.329 2170 22502 exclusion phecode
695.1 Toxic erythema Dermatologic 1.07 0.873 – 1.31 0.517 102 1042 exclusion phecode
695.2 Bullous dermatoses Dermatologic 0.943 0.781 – 1.14 0.545 121 1271 exclusion phecode
695.21 Dermatitis herpetiformis Dermatologic 0.92 0.685 – 1.24 0.583 51 526 exclusion phecode
695.22 Pemphigus and pemphigoid Dermatologic 0.895 0.692 – 1.16 0.396 64 682 exclusion phecode
695.3 Rosacea Dermatologic 1.12 0.992 – 1.27 0.0679 283 2885 exclusion phecode
695.4 Lupus (localized and systemic) Dermatologic 0.89 0.802 – 0.988 0.0285 391 3938 exclusion phecode
695.41 Cutaneous lupus erythematosus Dermatologic 0.948 0.789 – 1.14 0.568 124 1232 exclusion phecode
695.42 Systemic lupus erythematosus Dermatologic 0.873 0.778 – 0.979 0.0201 323 3265 exclusion phecode
695.7 Prurigo and Lichen Dermatologic 0.968 0.897 – 1.05 0.411 706 7357 exclusion phecode
695.8 Other specified erythematous conditions Dermatologic 1.07 0.927 – 1.23 0.362 210 2244 exclusion phecode
695.81 Erythema nodosum Dermatologic 1.01 0.794 – 1.3 0.906 71 730 exclusion phecode
695.9 Unspecified erythematous condition Dermatologic 0.909 0.821 – 1.01 0.0627 417 4368 exclusion phecode
696 Psoriasis and related disorders Dermatologic 1.01 0.962 – 1.05 0.757 1999 21181 exclusion phecode
696.4 Psoriasis Dermatologic 1.01 0.967 – 1.06 0.579 1949 20688 exclusion phecode
696.41 Psoriasis vulgaris Dermatologic 1.03 0.976 – 1.09 0.293 1482 15771 exclusion phecode
696.42 Psoriatic arthropathy Dermatologic 0.961 0.885 – 1.04 0.347 627 6658 exclusion phecode
697 Sarcoidosis Dermatologic 0.994 0.905 – 1.09 0.894 487 5093 exclusion phecode
698 Pruritus and related conditions Dermatologic 1 0.927 – 1.08 0.977 713 7402 exclusion phecode
700 Corns and callosities Dermatologic 0.9 0.793 – 1.02 0.104 268 2749 exclusion phecode
701
Other hypertrophic and atrophic conditions of
Other hypertrophic and atrophic conditions of skin
 Dermatologic 0.977 0.947 – 1.01 0.141 4339 44148 exclusion phecode
701.1 Keratoderma, acquired Dermatologic 0.834 0.662 – 1.05 0.125 81 797 exclusion phecode
701.2 Scar conditions and fibrosis of skin Dermatologic 0.955 0.914 – 0.998 0.0414 2223 22237 exclusion phecode
701.3 Circumscribed scleroderma Dermatologic 1.31 0.994 – 1.73 0.0549 54 587 exclusion phecode
701.4 Keloid scar Dermatologic 1 0.866 – 1.16 0.984 202 2074 exclusion phecode
701.5 Abnormal granulation tissue Dermatologic 0.956 0.866 – 1.06 0.377 422 4348 exclusion phecode
701.6 Acquired acanthosis nigricans Dermatologic 1.09 0.881 – 1.34 0.441 92 974 exclusion phecode
702
Degenerative skin conditions and other
Degenerative skin conditions and other dermatoses
 Dermatologic 0.994 0.966 – 1.02 0.688 5152 51237 exclusion phecode
702.1 Actinic keratosis Dermatologic 0.988 0.948 – 1.03 0.586 2428 24225 exclusion phecode
702.2 Seborrheic keratosis Dermatologic 1 0.963 – 1.04 0.995 2921 28890 exclusion phecode
703 Diseases of nail, NOS Dermatologic 1 0.894 – 1.12 0.996 320 3332 exclusion phecode
703.1 Ingrowing nail Dermatologic 0.98 0.913 – 1.05 0.568 838 9124 exclusion phecode
704 Diseases of hair and hair follicles Dermatologic 1.01 0.978 – 1.04 0.617 4979 49801 exclusion phecode
704.1 Alopecia Dermatologic 1.03 0.854 – 1.23 0.787 117 1225 exclusion phecode
704.8
Other specified diseases of hair and hair
Other specified diseases of hair and hair follicles
 Dermatologic 0.94 0.743 – 1.19 0.605 74 717 exclusion phecode
705 Disorders of sweat glands Dermatologic 0.957 0.83 – 1.1 0.54 201 2187 exclusion phecode
705.3 Hidradenitis Dermatologic 0.97 0.831 – 1.13 0.696 164 1796 exclusion phecode
705.8 Hyperhidrosis Dermatologic 1.02 0.93 – 1.11 0.727 540 5540 exclusion phecode
706 Diseases of sebaceous glands Dermatologic 1.01 0.982 – 1.03 0.667 7841 78625 exclusion phecode
706.1 Acne Dermatologic 1.22 0.974 – 1.54 0.0835 73 733 exclusion phecode
706.2 Sebaceous cyst Dermatologic 1 0.981 – 1.03 0.754 8282 83006 exclusion phecode
707 Chronic ulcer of skin Dermatologic 0.956 0.905 – 1.01 0.107 1374 18299 exclusion phecode
707.1 Decubitus ulcer Dermatologic 0.958 0.888 – 1.03 0.26 727 8446 exclusion phecode
709 Diffuse diseases of connective tissue Dermatologic 1.01 0.975 – 1.05 0.527 3018 32437 exclusion phecode
709.2 Sicca syndrome Dermatologic 1.01 0.919 – 1.11 0.848 479 4856 exclusion phecode
709.3 Systemic sclerosis Dermatologic 1.13 0.96 – 1.32 0.143 163 1671 exclusion phecode
709.6
Other specified diffuse diseases of connective
Other specified diffuse diseases of connective tissue
 Dermatologic 1.07 0.83 – 1.38 0.603 61 614 exclusion phecode
709.7 Unspecified diffuse connective tissue disease Dermatologic 1.01 0.968 – 1.05 0.661 2346 25597 exclusion phecode
710
Osteomyelitis, periostitis, and other
Osteomyelitis, periostitis, and other infections involving bone
 Musculoskeletal 0.989 0.898 – 1.09 0.827 427 5631 exclusion phecode
710.1 Osteomyelitis Musculoskeletal 1 0.907 – 1.11 0.949 387 5206 exclusion phecode
710.12 Chronic osteomyelitis Musculoskeletal 0.911 0.775 – 1.07 0.263 154 1841 exclusion phecode
710.19 Unspecified osteomyelitis Musculoskeletal 1.04 0.921 – 1.18 0.522 253 3710 exclusion phecode
711 Arthropathy associated with infections Musculoskeletal 0.941 0.848 – 1.05 0.259 368 3990 exclusion phecode
711.1 Pyogenic arthritis Musculoskeletal 0.97 0.861 – 1.09 0.618 282 3105 exclusion phecode
712 Infective connective tissue disorders Musculoskeletal 0.988 0.79 – 1.24 0.915 73 758 exclusion phecode
713
Arthropathy associated with other disorders
Arthropathy associated with other disorders classified elsewhere
 Musculoskeletal 0.936 0.748 – 1.17 0.56 81 1415 exclusion phecode
713.5
Arthropathy associated with neurological
Arthropathy associated with neurological disorders
 Musculoskeletal 1.1 0.571 – 2.1 0.783 6 620 exclusion phecode
714
Rheumatoid arthritis and other inflammatory
Rheumatoid arthritis and other inflammatory polyarthropathies
 Musculoskeletal 1.07 1.04 – 1.11 1.1e-05 4357 45792 exclusion phecode
714.1 Rheumatoid arthritis Musculoskeletal 1.08 1.05 – 1.12 1.13e-06 3953 41437 exclusion phecode
715 Other inflammatory spondylopathies Musculoskeletal 1.03 0.98 – 1.09 0.225 1511 15657 exclusion phecode
715.1 Sacroiliitis NEC Musculoskeletal 1 0.823 – 1.22 0.975 106 1087 exclusion phecode
715.2 Ankylosing spondylitis Musculoskeletal 1.14 1.05 – 1.24 0.00265 567 5804 exclusion phecode
716 Other arthropathies Musculoskeletal 0.996 0.985 – 1.01 0.473 34189 251534 exclusion phecode
716.1 Unspecified polyarthropathy or polyarthritis Musculoskeletal 0.983 0.948 – 1.02 0.366 3136 33100 exclusion phecode
716.2 Unspecified monoarthritis Musculoskeletal 0.985 0.968 – 1 0.0869 14255 146413 exclusion phecode
716.9 Arthropathy NOS Musculoskeletal 0.997 0.985 – 1.01 0.577 32782 248570 exclusion phecode
717 Polymyalgia Rheumatica Musculoskeletal 1.13 1.06 – 1.2 0.000197 1056 10755 exclusion phecode
720 Spinal stenosis Musculoskeletal 0.998 0.964 – 1.03 0.927 3327 34811 exclusion phecode
721 Spondylosis and allied disorders Musculoskeletal 1 0.979 – 1.03 0.771 7082 73821 exclusion phecode
721.1 Spondylosis without myelopathy Musculoskeletal 0.988 0.958 – 1.02 0.419 4568 47580 exclusion phecode
721.2 Spondylosis with myelopathy Musculoskeletal 1.1 0.935 – 1.28 0.259 162 1779 exclusion phecode
721.8 Other allied disorders of spine Musculoskeletal 1.09 0.976 – 1.23 0.124 322 3334 exclusion phecode
722 Intervertebral disc disorders Musculoskeletal 1 0.98 – 1.03 0.831 8258 85149 exclusion phecode
722.1 Displacement of intervertebral disc Musculoskeletal 1.06 0.964 – 1.16 0.233 469 4833 exclusion phecode
722.6 Degeneration of intervertebral disc Musculoskeletal 1.01 0.974 – 1.06 0.498 2598 26876 exclusion phecode
722.8 Postlaminectomy syndrome Musculoskeletal 1.19 0.929 – 1.52 0.17 65 636 exclusion phecode
722.9 Other and unspecified disc disorder Musculoskeletal 1 0.972 – 1.04 0.824 4073 41781 exclusion phecode
723 Other disorders of cervical region Musculoskeletal 1.02 0.926 – 1.11 0.75 475 4864 exclusion phecode
723.1 Torticollis Musculoskeletal 1.22 0.997 – 1.5 0.0532 100 1017 exclusion phecode
724 Other and unspecified disorders of back Musculoskeletal 1.03 0.98 – 1.08 0.271 1902 19394 exclusion phecode
724.1 Disorders of sacrum Musculoskeletal 0.981 0.883 – 1.09 0.729 383 3847 exclusion phecode
724.2 Disorders of coccyx Musculoskeletal 0.987 0.887 – 1.1 0.811 386 3872 exclusion phecode
724.8 Other symptoms referable to back Musculoskeletal 1.35 1.02 – 1.78 0.0345 57 606 exclusion phecode
724.9 Other unspecified back disorders Musculoskeletal 1.03 0.976 – 1.09 0.286 1490 15196 exclusion phecode
726 Peripheral enthesopathies and allied syndromes Musculoskeletal 1 0.984 – 1.02 0.858 13398 138816 exclusion phecode
726.1 Enthesopathy Musculoskeletal 0.999 0.977 – 1.02 0.932 8757 90645 exclusion phecode
726.2 Synoviopathy Musculoskeletal 1.06 0.949 – 1.19 0.287 308 3177 exclusion phecode
726.3 Bursitis Musculoskeletal 1.03 0.954 – 1.11 0.483 765 8075 exclusion phecode
727 Other disorders of synovium, tendon, and bursa Musculoskeletal 1.03 1 – 1.05 0.0412 6854 69603 exclusion phecode
727.1 Synovitis and tenosynovitis Musculoskeletal 1.01 0.974 – 1.06 0.485 2522 26036 exclusion phecode
727.2 Bursitis disorders Musculoskeletal 0.936 0.756 – 1.16 0.547 92 978 exclusion phecode
727.4 Ganglion and cyst of synovium, tendon, and bursa Musculoskeletal 1.04 1 – 1.08 0.0343 2939 29661 exclusion phecode
727.5 Rupture of synovium Musculoskeletal 1.02 0.933 – 1.11 0.69 542 5507 exclusion phecode
727.6 Rupture of tendon, nontraumatic Musculoskeletal 1.03 0.925 – 1.16 0.55 330 3313 exclusion phecode
727.7 Contracture of tendon (sheath) Musculoskeletal 0.945 0.794 – 1.12 0.519 136 1360 exclusion phecode
728 Disorders of muscle, ligament, and fascia Musculoskeletal 1.06 1.02 – 1.1 0.00236 3324 34058 exclusion phecode
728.2 Laxity of ligament or hypermobility syndrome Musculoskeletal 0.976 0.88 – 1.08 0.648 395 3962 exclusion phecode
728.7 Fasciitis Musculoskeletal 1.05 1.02 – 1.09 0.00309 3444 35266 exclusion phecode
728.71
Contracture of palmar fascia [Dupuytren's
Contracture of palmar fascia [Dupuytren's disease]
 Musculoskeletal 1.06 1.03 – 1.1 0.000828 3141 32186 exclusion phecode
729 Other disorders of soft tissues Musculoskeletal 0.992 0.964 – 1.02 0.551 5430 57052 exclusion phecode
729.1 Rheumatism, unspecified and fibrositis Musculoskeletal 1.01 0.941 – 1.08 0.832 906 9645 exclusion phecode
729.3 Panniculitis Musculoskeletal 0.788 0.634 – 0.98 0.0323 93 966 exclusion phecode
731
Osteitis deformans and osteopathies associated
Osteitis deformans and osteopathies associated with other disorders classified elsewhere
 Musculoskeletal 1.09 0.957 – 1.24 0.201 257 2633 exclusion phecode
731.1 Osteitis deformans [Paget's disease of bone] Musculoskeletal 1.07 0.937 – 1.22 0.327 243 2487 exclusion phecode
732 Osteochondropathies Musculoskeletal 0.907 0.819 – 1 0.0599 447 4441 exclusion phecode
732.1 Juvenile osteochondrosis Musculoskeletal 0.923 0.791 – 1.08 0.306 195 1952 exclusion phecode
732.7 Osteochondritis dissecans Musculoskeletal 0.861 0.654 – 1.14 0.29 57 541 exclusion phecode
733 Other disorders of bone and cartilage Musculoskeletal 0.957 0.91 – 1.01 0.0888 1668 16864 exclusion phecode
733.2 Cyst of bone Musculoskeletal 0.887 0.789 – 0.997 0.0451 299 2943 exclusion phecode
733.4 Aseptic necrosis of bone Musculoskeletal 1.04 0.951 – 1.14 0.381 499 5091 exclusion phecode
733.6 Costochondritis Musculoskeletal 0.859 0.708 – 1.04 0.121 122 1218 exclusion phecode
733.8 Malunion and nonunion of fracture Musculoskeletal 1.05 0.991 – 1.12 0.0939 1154 11673 exclusion phecode
733.9 Chondromalacia Musculoskeletal 1.03 0.849 – 1.25 0.766 114 1150 exclusion phecode
735 Acquired foot deformities Musculoskeletal 1.01 0.985 – 1.03 0.552 9254 91386 exclusion phecode
735.1 Flat foot Musculoskeletal 0.948 0.817 – 1.1 0.486 185 1810 exclusion phecode
735.2 Acquired toe deformities Musculoskeletal 1.01 0.976 – 1.04 0.727 4866 48115 exclusion phecode
735.21 Hammer toe (acquired) Musculoskeletal 0.995 0.948 – 1.04 0.83 1850 18337 exclusion phecode
735.23 Hallux rigidus Musculoskeletal 1.04 0.982 – 1.09 0.199 1498 14710 exclusion phecode
735.3 Hallux valgus (Bunion) Musculoskeletal 1 0.978 – 1.03 0.796 6437 63406 exclusion phecode
736 Other acquired deformities of limbs Musculoskeletal 1.02 0.972 – 1.08 0.375 1512 15264 exclusion phecode
736.2 Acquired deformities of finger Musculoskeletal 1.04 0.91 – 1.18 0.589 239 2337 exclusion phecode
737 Curvature of spine Musculoskeletal 0.981 0.921 – 1.04 0.539 1067 10715 exclusion phecode
737.3 Kyphoscoliosis and scoliosis Musculoskeletal 0.982 0.921 – 1.05 0.583 1008 10064 exclusion phecode
738 Other acquired musculoskeletal deformity Musculoskeletal 0.978 0.931 – 1.03 0.377 1753 18065 exclusion phecode
738.4 Acquired spondylolisthesis Musculoskeletal 0.989 0.936 – 1.04 0.682 1392 14362 exclusion phecode
739 Contracture of joint Musculoskeletal 1.04 0.942 – 1.14 0.474 454 4621 exclusion phecode
740 Osteoarthrosis Musculoskeletal 1 0.99 – 1.02 0.611 25395 218276 exclusion phecode
740.1 Osteoarthritis; localized Musculoskeletal 1.01 0.989 – 1.02 0.513 16122 159216 exclusion phecode
740.11 Osteoarthrosis, localized, primary Musculoskeletal 1 0.981 – 1.03 0.789 8251 84140 exclusion phecode
740.12 Osteoarthrosis, localized, secondary Musculoskeletal 1.09 0.973 – 1.22 0.139 327 3292 exclusion phecode
740.2 Osteoarthrosis, generalized Musculoskeletal 1.01 0.929 – 1.11 0.741 551 5605 exclusion phecode
740.9 Osteoarthrosis NOS Musculoskeletal 0.999 0.979 – 1.02 0.888 11062 115758 exclusion phecode
741 Symptoms and disorders of the joints Musculoskeletal 1.02 0.985 – 1.06 0.266 3265 33551 exclusion phecode
741.1 Ankylosis of joint Musculoskeletal 1.11 0.908 – 1.36 0.306 96 953 exclusion phecode
741.2 Stiffness of joint Musculoskeletal 1 0.923 – 1.09 0.912 569 5806 exclusion phecode
741.3 Difficulty in walking Musculoskeletal 0.88 0.733 – 1.06 0.171 126 1431 exclusion phecode
741.4 Joint effusions Musculoskeletal 1.1 1.04 – 1.16 0.00139 1283 13289 exclusion phecode
741.5 Hemarthrosis Musculoskeletal 1.16 0.949 – 1.41 0.15 101 1036 exclusion phecode
741.6 Villonodular synovitis Musculoskeletal 0.963 0.731 – 1.27 0.791 51 514 exclusion phecode
742 Derangement of joint, non-traumatic Musculoskeletal 1 0.964 – 1.04 0.885 2680 27102 exclusion phecode
742.1 Loose body in joint Musculoskeletal 0.999 0.892 – 1.12 0.982 315 3159 exclusion phecode
742.2
Pathological, developmental or recurrent
Pathological, developmental or recurrent dislocation
 Musculoskeletal 1.05 0.856 – 1.3 0.618 87 934 exclusion phecode
742.8 Articular cartilage disorder Musculoskeletal 1.06 0.964 – 1.16 0.234 459 4762 exclusion phecode
742.9 Other derangement of joint Musculoskeletal 0.989 0.943 – 1.04 0.635 1898 19016 exclusion phecode
743
Osteoporosis, osteopenia and pathological
Osteoporosis, osteopenia and pathological fracture
 Musculoskeletal 0.986 0.963 – 1.01 0.27 7063 71598 exclusion phecode
743.1 Osteoporosis Musculoskeletal 0.978 0.952 – 1 0.0945 5975 60607 exclusion phecode
743.11 Osteoporosis NOS Musculoskeletal 0.98 0.952 – 1.01 0.164 5187 52642 exclusion phecode
743.13 Other specified osteoporosis Musculoskeletal 1.03 0.936 – 1.12 0.589 487 4960 exclusion phecode
743.2 Pathologic fracture Musculoskeletal 0.97 0.884 – 1.06 0.524 470 4849 exclusion phecode
743.9
Osteopenia or other disorder of bone and
Osteopenia or other disorder of bone and cartilage
 Musculoskeletal 1.06 0.986 – 1.14 0.113 771 7736 exclusion phecode
745 Pain in joint Musculoskeletal 0.982 0.959 – 1.01 0.142 7314 75549 exclusion phecode
747 Cardiac and circulatory congenital anomalies Congenital Anomalies 0.987 0.946 – 1.03 0.53 2444 26246 exclusion phecode
747.1 Cardiac congenital anomalies Congenital Anomalies 0.986 0.944 – 1.03 0.509 2282 24611 exclusion phecode
747.11 Cardiac shunt/ heart septal defect Congenital Anomalies 1.05 0.958 – 1.14 0.313 552 5570 exclusion phecode
747.12 Valvular heart disease/ heart chambers Congenital Anomalies 1.03 0.901 – 1.18 0.652 222 2232 exclusion phecode
747.13 Congenital anomalies of great vessels Congenital Anomalies 0.989 0.938 – 1.04 0.692 1517 16840 exclusion phecode
747.2
Congenital anomalies of peripheral vascular
Congenital anomalies of peripheral vascular system
 Congenital Anomalies 0.936 0.793 – 1.11 0.435 154 1589 exclusion phecode
748 Anomalies of respiratory system, congenital Congenital Anomalies 0.929 0.703 – 1.23 0.602 49 479 exclusion phecode
749 Congenital anomalies of face and neck Congenital Anomalies 0.953 0.843 – 1.08 0.434 282 2892 exclusion phecode
750 Digestive congenital anomalies Congenital Anomalies 0.91 0.839 – 0.986 0.0219 646 6422 exclusion phecode
750.1 Upper gastrointestinal congenital anomalies Congenital Anomalies 0.869 0.772 – 0.979 0.0211 304 3046 exclusion phecode
750.13 Congenital anomalies of mouth/tongue Congenital Anomalies 0.901 0.775 – 1.05 0.175 182 1772 exclusion phecode
750.2 Lower gastrointestinal congenital anomalies Congenital Anomalies 0.947 0.847 – 1.06 0.334 338 3363 exclusion phecode
750.21 Congenital anomalies of intestine Congenital Anomalies 0.933 0.812 – 1.07 0.326 217 2115 exclusion phecode
750.22
Congenital anomaly of gallbladder, bile ducts
Congenital anomaly of gallbladder, bile ducts, liver, pancreas
 Congenital Anomalies 1.01 0.834 – 1.23 0.907 110 1119 exclusion phecode
751 Genitourinary congenital anomalies Congenital Anomalies 0.95 0.9 – 1 0.0651 1418 14452 exclusion phecode
751.1 Congenital anomalies of genital organs Congenital Anomalies 0.986 0.911 – 1.07 0.732 661 6602 exclusion phecode
751.11 Congenital anomalies of female genital organs Congenital Anomalies 1.06 0.963 – 1.17 0.232 442 4394 exclusion phecode
751.12 Congenital anomalies of male genital organs Congenital Anomalies 0.892 0.77 – 1.03 0.13 202 2042 exclusion phecode
751.2 Congenital anomalies of urinary system Congenital Anomalies 0.915 0.849 – 0.986 0.0193 759 7863 exclusion phecode
751.21 Cystic kidney disease Congenital Anomalies 0.879 0.79 – 0.977 0.0167 380 3981 exclusion phecode
751.22 Other specified congenital anomalies of kidney Congenital Anomalies 0.979 0.87 – 1.1 0.729 301 3141 exclusion phecode
752 Nervous system congenital anomalies Congenital Anomalies 0.888 0.789 – 0.999 0.0481 310 3151 exclusion phecode
752.1 Neural tube defects Congenital Anomalies 0.868 0.76 – 0.992 0.0374 242 2440 exclusion phecode
752.11 Spina bifida Congenital Anomalies 0.83 0.717 – 0.96 0.0122 201 2013 exclusion phecode
752.2
Other specified congenital anomalies of nervous
Other specified congenital anomalies of nervous system
 Congenital Anomalies 0.92 0.716 – 1.18 0.514 71 739 exclusion phecode
753 Congenital anomalies of the eye Congenital Anomalies 1.05 0.866 – 1.27 0.63 120 1197 exclusion phecode
753.1 Congenital cataract and lens anomalies Congenital Anomalies 0.905 0.702 – 1.17 0.438 72 716 exclusion phecode
754 Congenital musculoskeletal deformities of spine Congenital Anomalies 1.05 0.859 – 1.28 0.645 103 1041 exclusion phecode
755 Congenital anomalies of limbs Congenital Anomalies 0.994 0.897 – 1.1 0.91 408 4087 exclusion phecode
755.1 Congenital deformities of feet Congenital Anomalies 1.03 0.892 – 1.19 0.674 193 1984 exclusion phecode
755.6
Other congenital anomalies of lower limb
Other congenital anomalies of lower limb, including pelvic girdle
 Congenital Anomalies 0.962 0.816 – 1.13 0.646 159 1556 exclusion phecode
755.61 Congenital hip dysplasia and deformity Congenital Anomalies 0.948 0.775 – 1.16 0.605 106 1033 exclusion phecode
756 Other congenital musculoskeletal anomalies Congenital Anomalies 1 0.919 – 1.09 0.956 553 5548 exclusion phecode
756.3
Congenital anomalies of muscle, tendon, fascia
Congenital anomalies of muscle, tendon, fascia, and connective tissue
 Congenital Anomalies 1.07 0.856 – 1.34 0.54 78 768 exclusion phecode
756.5 Congenital osteodystrophies Congenital Anomalies 1.01 0.913 – 1.12 0.826 408 4121 exclusion phecode
758 Chromosomal anomalies and genetic disorders Congenital Anomalies 0.939 0.795 – 1.11 0.457 142 1619 exclusion phecode
758.1 Chromosomal anomalies Congenital Anomalies 1.02 0.786 – 1.32 0.885 57 793 exclusion phecode
759 Other and unspecified congenital anomalies Congenital Anomalies 1.09 0.945 – 1.26 0.235 204 2055 exclusion phecode
759.1 Anomalies of endocrine glands, congenital Congenital Anomalies 1.02 0.83 – 1.26 0.845 91 912 exclusion phecode
760 Back pain Symptoms 0.985 0.965 – 1 0.136 10118 105492 exclusion phecode
761 Cervicalgia Symptoms 1.01 0.957 – 1.06 0.797 1629 16951 exclusion phecode
764 Sciatica Symptoms 0.982 0.939 – 1.03 0.409 2185 22486 exclusion phecode
766 Neuralgia, neuritis, and radiculitis NOS Symptoms 0.965 0.906 – 1.03 0.272 1070 11115 exclusion phecode
770 Myalgia and myositis unspecified Symptoms 1.05 0.961 – 1.14 0.294 569 5994 exclusion phecode
771 Musculoskeletal symptoms referable to limbs Symptoms 0.955 0.887 – 1.03 0.226 778 8187 exclusion phecode
771.1 Swelling of limb Symptoms 0.981 0.95 – 1.01 0.23 4161 43631 exclusion phecode
772 Symptoms of the muscles Symptoms 0.979 0.899 – 1.07 0.626 584 6195 exclusion phecode
773 Pain in limb Symptoms 0.985 0.959 – 1.01 0.294 5628 58848 exclusion phecode
780 Hypothermia/Chills Symptoms 0.855 0.722 – 1.01 0.072 140 1635 exclusion phecode
781
Symptoms involving nervous and musculoskeletal
Symptoms involving nervous and musculoskeletal systems
 Symptoms 0.975 0.927 – 1.02 0.32 1659 17686 exclusion phecode
782.3 Edema Symptoms 0.962 0.911 – 1.02 0.17 1365 15365 exclusion phecode
782.6 Pallor and flushing Symptoms 1.09 0.923 – 1.28 0.317 153 1650 exclusion phecode
783 Fever of unknown origin Symptoms 1.01 0.973 – 1.04 0.673 3539 36765 exclusion phecode
785 Abdominal pain Symptoms 1 0.994 – 1.02 0.405 37406 286103 exclusion phecode
788 Syncope and collapse Symptoms 0.998 0.976 – 1.02 0.89 8117 85154 exclusion phecode
789 Nausea and vomiting Symptoms 0.991 0.971 – 1.01 0.391 10410 109905 exclusion phecode
790 Nonspecific findings on examination of blood Symptoms 0.901 0.76 – 1.07 0.232 141 1405 exclusion phecode
790.1 Elevated sedimentation rate Symptoms 1.08 0.867 – 1.35 0.487 76 782 exclusion phecode
790.6 Other abnormal blood chemistry Symptoms 0.997 0.971 – 1.02 0.848 5705 58767 exclusion phecode
791 Gangrene Symptoms 0.959 0.863 – 1.07 0.436 382 5152 exclusion phecode
792
Abnormal Papanicolaou smear of cervix and
Abnormal Papanicolaou smear of cervix and cervical HPV
 Symptoms 1.01 0.81 – 1.25 0.953 95 925 exclusion phecode
793
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of musculoskeletal system
 Symptoms 0.993 0.823 – 1.2 0.944 116 1249 exclusion phecode
793.2
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of other intrathoracic organs (echocardiogram, etc)
 Symptoms 0.97 0.886 – 1.06 0.514 520 5317 exclusion phecode
794
Abnormal results of other function studies
Abnormal results of other function studies (bladder, pancreas, placenta, spleen, etc)
 Symptoms 0.924 0.766 – 1.12 0.413 113 1158 exclusion phecode
797 Shock Symptoms 0.892 0.749 – 1.06 0.202 126 1455 exclusion phecode
797.1 Cardiogenic shock Symptoms 0.984 0.788 – 1.23 0.886 75 944 exclusion phecode
798 Malaise and fatigue Symptoms 0.99 0.954 – 1.03 0.615 3074 32254 exclusion phecode
798.1 Chronic fatigue syndrome Symptoms 1.03 0.945 – 1.13 0.481 548 5681 exclusion phecode
800 Fracture of lower limb Injuries & Poisonings 1.03 1.01 – 1.06 0.0091 6478 66496 exclusion phecode
800.1 Fracture of neck of femur Injuries & Poisonings 0.962 0.914 – 1.01 0.132 1668 17025 exclusion phecode
800.2 Fracture of unspecified part of femur Injuries & Poisonings 1.07 0.906 – 1.26 0.427 151 1587 exclusion phecode
800.3 Fracture of tibia and fibula Injuries & Poisonings 1.06 1.01 – 1.11 0.0107 2001 20477 exclusion phecode
800.4 Fracture of patella Injuries & Poisonings 1.08 0.997 – 1.16 0.0597 709 7196 exclusion phecode
801 Fracture of ankle and foot Injuries & Poisonings 1.02 0.976 – 1.07 0.356 2048 20884 exclusion phecode
801.1 Fracture of foot Injuries & Poisonings 1.04 0.991 – 1.09 0.113 1708 17374 exclusion phecode
802 Fracture of pelvis Injuries & Poisonings 1.04 0.963 – 1.13 0.308 675 6757 exclusion phecode
803 Fracture of upper limb Injuries & Poisonings 0.996 0.973 – 1.02 0.756 7835 78638 exclusion phecode
803.1 Fracture of humerus Injuries & Poisonings 0.986 0.936 – 1.04 0.598 1532 15970 exclusion phecode
803.2 Fracture of radius and ulna Injuries & Poisonings 0.989 0.961 – 1.02 0.474 5004 49646 exclusion phecode
803.3 Fracture of clavicle or scapula Injuries & Poisonings 0.999 0.947 – 1.05 0.977 1422 14317 exclusion phecode
804 Fracture of hand or wrist Injuries & Poisonings 0.995 0.959 – 1.03 0.784 3172 31635 exclusion phecode
805
Fracture of vertebral column without mention of
Fracture of vertebral column without mention of spinal cord injury
 Injuries & Poisonings 1.06 1 – 1.12 0.0455 1253 12743 exclusion phecode
807 Fracture of ribs Injuries & Poisonings 1.01 0.936 – 1.09 0.815 723 7285 exclusion phecode
809 Fracture of unspecified bones Injuries & Poisonings 1.01 0.956 – 1.08 0.649 1195 12215 exclusion phecode
817 Concussion Injuries & Poisonings 0.946 0.827 – 1.08 0.415 228 2295 exclusion phecode
818 Intracranial hemorrhage (injury) Injuries & Poisonings 1.02 0.925 – 1.12 0.735 469 4844 exclusion phecode
819
Skull and face fracture and other intercranial
Skull and face fracture and other intercranial injury
 Injuries & Poisonings 1.01 0.969 – 1.05 0.695 2780 27999 exclusion phecode
823 Torus fracture Injuries & Poisonings 1.05 0.998 – 1.11 0.0603 1553 15891 exclusion phecode
830 Dislocation Injuries & Poisonings 1 0.956 – 1.05 0.966 1981 19750 exclusion phecode
835 Internal derangement of knee Injuries & Poisonings 0.999 0.982 – 1.02 0.915 14368 143917 exclusion phecode
836 Traumatic arthropathy Injuries & Poisonings 0.979 0.893 – 1.07 0.655 489 4961 exclusion phecode
840 Sprains and strains Injuries & Poisonings 1.05 0.953 – 1.15 0.328 455 4463 exclusion phecode
850 Hemorrhage or hematoma complicating a procedure Injuries & Poisonings 1.01 0.984 – 1.04 0.364 4831 49685 exclusion phecode
851
Complications of transplants and reattached
Complications of transplants and reattached limbs
 Injuries & Poisonings 0.897 0.757 – 1.06 0.21 142 1484 exclusion phecode
853 Complication of colostomy or enterostomy Injuries & Poisonings 0.981 0.891 – 1.08 0.704 445 4715 exclusion phecode
854
Complications of cardiac/vascular device
Complications of cardiac/vascular device, implant, and graft
 Injuries & Poisonings 0.968 0.918 – 1.02 0.223 1490 16959 exclusion phecode
857
Mechanical complication of unspecified
Mechanical complication of unspecified genitourinary device, implant, and graft
 Injuries & Poisonings 0.991 0.933 – 1.05 0.78 1115 11686 exclusion phecode
858 Complication of internal orthopedic device Injuries & Poisonings 1.02 0.978 – 1.05 0.42 2928 29749 exclusion phecode
859
Complication due to other implant and internal
Complication due to other implant and internal device
 Injuries & Poisonings 0.986 0.95 – 1.02 0.457 2992 30725 exclusion phecode
860 Bone marrow or stem cell transplant Neoplasms 1.08 0.84 – 1.39 0.554 63 644 exclusion phecode
870 Open wounds of head; neck; and trunk Injuries & Poisonings 0.993 0.959 – 1.03 0.721 3232 32981 exclusion phecode
870.1 Open wound or laceration of eye or eyelid Injuries & Poisonings 0.932 0.819 – 1.06 0.281 253 2529 exclusion phecode
870.2 Open wound of ear Injuries & Poisonings 0.925 0.795 – 1.08 0.316 179 1833 exclusion phecode
870.3 Other open wound of head and face Injuries & Poisonings 0.995 0.957 – 1.03 0.798 2688 27359 exclusion phecode
870.4 Open wound of nose and sinus Injuries & Poisonings 0.901 0.783 – 1.04 0.141 205 2060 exclusion phecode
870.6 Open wound of neck Injuries & Poisonings 1.05 0.828 – 1.33 0.681 62 648 exclusion phecode
871 Open wounds of extremities Injuries & Poisonings 1.01 0.981 – 1.05 0.42 3818 38378 exclusion phecode
871.1 Open wound of hand except finger(s) Injuries & Poisonings 1.08 0.812 – 1.44 0.587 48 492 exclusion phecode
871.2 Open wound of finger(s) Injuries & Poisonings 1.06 0.851 – 1.32 0.609 85 831 exclusion phecode
871.3 Open wound of foot except toe(s) alone Injuries & Poisonings 0.994 0.847 – 1.17 0.937 152 1697 exclusion phecode
872 Traumatic amputation Injuries & Poisonings 0.975 0.885 – 1.07 0.604 445 4452 exclusion phecode
873 Broken tooth Injuries & Poisonings 1.05 0.913 – 1.21 0.492 206 2153 exclusion phecode
874 Complication of amputation stump Injuries & Poisonings 1.09 0.907 – 1.32 0.347 118 1601 exclusion phecode
905
Late effects of musculoskeletal and connective
Late effects of musculoskeletal and connective tissue injuries
 Injuries & Poisonings 0.901 0.763 – 1.06 0.221 147 1473 exclusion phecode
907 Injuries to the nervous system Injuries & Poisonings 0.973 0.918 – 1.03 0.346 1248 12415 exclusion phecode
915 Superficial injury without mention of infection Injuries & Poisonings 0.982 0.95 – 1.01 0.273 3823 40191 exclusion phecode
916 Contusion Injuries & Poisonings 1 0.945 – 1.06 0.992 1326 13662 exclusion phecode
930 Allergic reaction to food Injuries & Poisonings 0.913 0.778 – 1.07 0.266 166 1721 exclusion phecode
938 Dermatitis due to solar radiation Injuries & Poisonings 0.95 0.854 – 1.06 0.348 363 3639 exclusion phecode
938.2 Chronic dermatitis due to solar radiation Injuries & Poisonings 0.974 0.854 – 1.11 0.697 236 2354 exclusion phecode
939
Atopic/contact dermatitis due to other or
Atopic/contact dermatitis due to other or unspecified
 Dermatologic 0.97 0.926 – 1.02 0.2 1938 19711 exclusion phecode
941 Adverse reaction to serum or vaccine Injuries & Poisonings 0.923 0.798 – 1.07 0.279 204 2116 exclusion phecode
942 Infusion and transfusion reaction Injuries & Poisonings 1.03 0.847 – 1.27 0.738 98 986 exclusion phecode
946 Anaphylactic shock NOS Injuries & Poisonings 1.05 0.955 – 1.15 0.326 487 5239 exclusion phecode
947 Urticaria Injuries & Poisonings 1.05 0.941 – 1.17 0.387 348 3538 exclusion phecode
949 Allergies, other Injuries & Poisonings 1.04 0.937 – 1.16 0.455 367 3816 exclusion phecode
952
Spinal cord injury without evidence of spinal
Spinal cord injury without evidence of spinal bone injury
 Injuries & Poisonings 1.09 0.984 – 1.21 0.0978 386 3967 exclusion phecode
957 Injury to other and unspecified nerves Injuries & Poisonings 1.1 0.966 – 1.26 0.148 248 2544 exclusion phecode
958
Certain early complications of trauma or
Certain early complications of trauma or procedure
 Injuries & Poisonings 0.939 0.852 – 1.03 0.204 447 4626 exclusion phecode
958.1 Postoperative shock Injuries & Poisonings 1.05 0.758 – 1.46 0.764 43 509 exclusion phecode
958.2 Traumatic and surgical subcutaneous emphysema Injuries & Poisonings 0.855 0.674 – 1.09 0.198 70 685 exclusion phecode
960 Poisoning by antibiotics Injuries & Poisonings 0.988 0.972 – 1 0.124 16634 172453 exclusion phecode
960.2 Allergy/adverse effect of penicillin Injuries & Poisonings 0.985 0.968 – 1 0.0811 14535 150937 exclusion phecode
961 Poisoning by other anti-infectives Injuries & Poisonings 1.03 0.927 – 1.14 0.595 380 3984 exclusion phecode
961.1 Poisoning/allergy of sulfonamides Injuries & Poisonings 1.04 0.97 – 1.12 0.266 806 8332 exclusion phecode
962 Poisoning by hormones and synthetic substitutes Injuries & Poisonings 0.989 0.88 – 1.11 0.852 315 3517 exclusion phecode
962.3
Hormones and synthetic substitutes causing
Hormones and synthetic substitutes causing adverse effects in therapeutic use
 Injuries & Poisonings 1 0.891 – 1.13 0.982 307 3449 exclusion phecode
963 Poisoning by primarily systemic agents Injuries & Poisonings 1.06 0.918 – 1.22 0.435 210 2118 exclusion phecode
964
Poisoning by agents primarily affecting blood
Poisoning by agents primarily affecting blood constituents
 Injuries & Poisonings 0.953 0.835 – 1.09 0.471 240 2617 exclusion phecode
964.1 Anticoagulants causing adverse effects Injuries & Poisonings 0.962 0.841 – 1.1 0.573 234 2561 exclusion phecode
965
Poisoning by analgesics, antipyretics, and
Poisoning by analgesics, antipyretics, and antirheumatics
 Injuries & Poisonings 1.01 0.984 – 1.04 0.407 5530 57958 exclusion phecode
965.1
Opiates and related narcotics causing adverse
Opiates and related narcotics causing adverse effects in therapeutic use
 Injuries & Poisonings 0.971 0.91 – 1.04 0.362 1038 10963 exclusion phecode
965.2
Antirheumatics causing adverse effects in
Antirheumatics causing adverse effects in therapeutic use
 Injuries & Poisonings 0.95 0.86 – 1.05 0.313 433 4576 exclusion phecode
965.3
Salicylates causing adverse effects in
Salicylates causing adverse effects in therapeutic use
 Injuries & Poisonings 1.05 0.943 – 1.17 0.382 357 3825 exclusion phecode
966
Poisoning by anticonvulsants and
Poisoning by anticonvulsants and anti-Parkinsonism drugs
 Injuries & Poisonings 1.02 0.926 – 1.12 0.678 467 4894 exclusion phecode
967
Adverse effects of sedatives or other central
Adverse effects of sedatives or other central nervous system depressants and anesthetics
 Injuries & Poisonings 1 0.92 – 1.1 0.912 542 5559 exclusion phecode
969 Poisoning by psychotropic agents Injuries & Poisonings 1.01 0.961 – 1.06 0.713 1767 18683 exclusion phecode
971
Poisoning by drugs primarily affecting the
Poisoning by drugs primarily affecting the autonomic nervous system
 Injuries & Poisonings 1.07 0.919 – 1.25 0.382 168 1828 exclusion phecode
972
Poisoning by agents primarily affecting the
Poisoning by agents primarily affecting the cardiovascular system
 Injuries & Poisonings 1.06 0.929 – 1.21 0.384 227 2590 exclusion phecode
972.6 Antihypertensive agents causing adverse effects Injuries & Poisonings 0.921 0.715 – 1.19 0.524 70 809 exclusion phecode
973
Poisoning by agents primarily affecting the
Poisoning by agents primarily affecting the gastrointestinal system
 Injuries & Poisonings 1.01 0.825 – 1.24 0.906 96 1021 exclusion phecode
974
Poisoning by water, mineral, and uric acid
Poisoning by water, mineral, and uric acid metabolism drugs
 Injuries & Poisonings 1.11 0.9 – 1.38 0.319 83 947 exclusion phecode
975
Poisoning by agents primarily acting on the
Poisoning by agents primarily acting on the smooth and skeletal muscles and respiratory system
 Injuries & Poisonings 0.968 0.732 – 1.28 0.818 58 611 exclusion phecode
976
Poisoning by agents primarily affecting skin &
Poisoning by agents primarily affecting skin & mucous membrane, ophthalmological, otorhinolaryngological, & dental drugs
 Injuries & Poisonings 0.995 0.758 – 1.31 0.972 52 555 exclusion phecode
977 Personal history of allergy to medicinal agents Injuries & Poisonings 0.942 0.82 – 1.08 0.395 215 2208 exclusion phecode
979 Adverse drug events and drug allergies Injuries & Poisonings 0.992 0.914 – 1.08 0.84 636 6637 exclusion phecode
981
Toxic effect of (non-ethyl) alcohol and
Toxic effect of (non-ethyl) alcohol and petroleum and other solvents
 Injuries & Poisonings 0.963 0.828 – 1.12 0.621 182 1903 exclusion phecode
986 Toxic effect of carbon monoxide Injuries & Poisonings 0.949 0.727 – 1.24 0.703 58 584 exclusion phecode
987 Toxic effect of other gases, fumes, or vapors Injuries & Poisonings 1.06 0.861 – 1.31 0.578 93 988 exclusion phecode
988 Toxic effect of noxious substances eaten as food Injuries & Poisonings 0.784 0.639 – 0.96 0.0188 102 1060 exclusion phecode
989
Toxic effect of other substances, chiefly
Toxic effect of other substances, chiefly nonmedicinal as to source
 Injuries & Poisonings 0.915 0.73 – 1.15 0.444 86 840 exclusion phecode
990 Effects radiation NOS Injuries & Poisonings 0.995 0.957 – 1.03 0.782 2856 29168 exclusion phecode
994 Sepsis and SIRS Injuries & Poisonings 0.958 0.92 – 0.998 0.0377 2636 28313 exclusion phecode
994.2 Sepsis Injuries & Poisonings 0.958 0.92 – 0.998 0.0377 2636 28313 exclusion phecode
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