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Scores Type 2 diabetes UK Biobank (UKB) PheWAS analysis

Type 2 diabetes — UK Biobank (UKB) PRS PheWAS

PRS model
PRS ID exprsweb-t2d-30054458-gcst006867-plink-ukb-20211120Legacy PLINKC+T (GT)Large GWAS

Evaluation cohort: UK Biobank (UKB).

This page pairs the PheWAS plot with the full sortable table for the all-subject and exclusion scans.

Read the all-subject and exclusion scans separately. The combined view is only a browsing aid, and the selected-phecode panel below is only meaningful when the same phecode exists in both scans.

ExPRS exclusion definition

Exclusion cohort: individuals without Type 2 diabetes.

For this ExPRS, the exclusion sensitivity scan removes individuals with the exposure itself before rerunning the PheWAS. This is an exposure-based sensitivity analysis rather than a diagnosis-based exclusion.

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Signal overview

The plot gives a quick view of the currently visible associations. Click a point to pin its details, inspect that phecode across scans when both rows exist, or open the matching phecode detail page.

976 rows visible 17 categories
Phecode Description Category OR 95% CI P value Cases Controls Analysis Link
008 Intestinal infection Infectious Diseases 1.19 1.16 – 1.21 3.48e-56 8842 88430 all phecode
008.5 Bacterial enteritis Infectious Diseases 1.18 1.14 – 1.23 1.67e-17 2718 27172 all phecode
008.52 Intestinal infection due to C. difficile Infectious Diseases 1.18 1.1 – 1.28 1.74e-05 653 6533 all phecode
008.6 Viral Enteritis Infectious Diseases 1.21 1.13 – 1.29 8.32e-08 862 8622 all phecode
008.7 Intestinal infection due to protozoa Infectious Diseases 1.2 0.93 – 1.56 0.159 55 550 all phecode
010 Tuberculosis Infectious Diseases 0.935 0.798 – 1.1 0.411 166 1659 all phecode
038 Septicemia Infectious Diseases 1.23 1.19 – 1.27 7.69e-39 4175 41776 all phecode
038.1 Gram negative septicemia Infectious Diseases 1.21 1.13 – 1.3 3.41e-08 850 8501 all phecode
038.2 Gram positive septicemia Infectious Diseases 1.27 1.16 – 1.38 1.04e-07 494 4978 all phecode
041 Bacterial infection NOS Infectious Diseases 1.24 1.22 – 1.26 6.6e-119 12017 120377 all phecode
041.1 Staphylococcus infections Infectious Diseases 1.31 1.27 – 1.36 8.36e-52 3128 31348 all phecode
041.2 Streptococcus infection Infectious Diseases 1.25 1.19 – 1.32 2.05e-19 1641 16433 all phecode
041.4 E. coli Infectious Diseases 1.26 1.21 – 1.31 1.73e-32 2730 27319 all phecode
053 Herpes zoster Infectious Diseases 1.18 1.07 – 1.31 0.000863 411 4137 all phecode
053.1 Herpes zoster with nervous system complications Infectious Diseases 1.27 1.03 – 1.57 0.0247 95 949 all phecode
054 Herpes simplex Infectious Diseases 1.04 0.905 – 1.2 0.557 211 2107 all phecode
070 Viral hepatitis Infectious Diseases 1.12 1.03 – 1.21 0.01 590 5916 all phecode
070.1 Viral hepatitis A Infectious Diseases 1.18 0.927 – 1.51 0.177 69 690 all phecode
070.2 Viral hepatitis B Infectious Diseases 1.09 0.911 – 1.3 0.355 132 1330 all phecode
070.3 Viral hepatitis C Infectious Diseases 1.12 0.98 – 1.27 0.0982 255 2568 all phecode
070.4 Chronic hepatitis Infectious Diseases 1.27 1.12 – 1.43 9.79e-05 276 2767 all phecode
070.9 Hepatitis NOS Infectious Diseases 1.53 1.39 – 1.68 6.59e-19 428 4287 all phecode
071 Human immunodeficiency virus [HIV] disease Infectious Diseases 1.01 0.856 – 1.19 0.893 147 1467 all phecode
071.1 HIV infection, symptomatic Infectious Diseases 1.01 0.842 – 1.22 0.897 117 1168 all phecode
078 Viral warts & HPV Infectious Diseases 1.13 1.06 – 1.21 0.000128 1004 10036 all phecode
079 Viral infection Infectious Diseases 1.12 1.07 – 1.16 3.7e-08 2769 27694 all phecode
079.1 Varicella infection Infectious Diseases 1.03 0.789 – 1.33 0.852 64 640 all phecode
080 Postoperative infection Infectious Diseases 1.25 1.21 – 1.29 2.21e-47 4473 44775 all phecode
081
Infection/inflammation of internal prosthetic
Infection/inflammation of internal prosthetic device; implant; and graft
 Infectious Diseases 1.18 1.14 – 1.23 2.33e-16 2477 24765 all phecode
090
Sexually transmitted infections (not HIV or
Sexually transmitted infections (not HIV or hepatitis)
 Infectious Diseases 1.14 0.893 – 1.45 0.296 71 709 all phecode
1000 Burns Injuries & Poisonings 1.07 0.984 – 1.16 0.113 578 5796 all phecode
1001 Foreign body injury Injuries & Poisonings 1.07 1.01 – 1.13 0.0219 1199 12007 all phecode
1002
Symptoms concerning nutrition, metabolism, and
Symptoms concerning nutrition, metabolism, and development
 Injuries & Poisonings 1.11 1.08 – 1.14 1.46e-13 5480 54819 all phecode
1004
Other signs and symptoms involving emotional
Other signs and symptoms involving emotional state
 Injuries & Poisonings 1.24 1.11 – 1.4 0.000298 300 2997 all phecode
1005 Other symptoms Injuries & Poisonings 1.21 1.15 – 1.28 1.13e-12 1444 14422 all phecode
1006 Crushing injury Injuries & Poisonings 0.949 0.835 – 1.08 0.419 256 2558 all phecode
1007 Injury to blood vessels Injuries & Poisonings 1.08 0.956 – 1.23 0.21 256 2559 all phecode
1008 Crushing or internal injury to organs Injuries & Poisonings 0.994 0.932 – 1.06 0.851 1013 10132 all phecode
1009 Injury, NOS Injuries & Poisonings 1.1 1.08 – 1.13 5.14e-18 8482 84911 all phecode
1010 Other tests Injuries & Poisonings 1.2 1.17 – 1.23 9.36e-44 5945 59512 all phecode
1011 Complications of surgical and medical procedures Injuries & Poisonings 1.17 1.14 – 1.19 2.26e-46 9152 91588 all phecode
1012 Late effect Injuries & Poisonings 1.06 0.87 – 1.29 0.559 105 1057 all phecode
1013 Asphyxia and hypoxemia Injuries & Poisonings 1.15 1.02 – 1.29 0.0182 316 3168 all phecode
1014 Effects of heat, cold and air pressure Injuries & Poisonings 1.18 0.916 – 1.51 0.202 66 659 all phecode
1015 Effects of other external causes Injuries & Poisonings 1.19 1.16 – 1.23 2.7e-29 4226 42294 all phecode
1019
Other ill-defined and unknown causes of
Other ill-defined and unknown causes of morbidity and mortality
 Injuries & Poisonings 1.13 1.11 – 1.15 8.19e-52 15895 159019 all phecode
110 Dermatophytosis / Dermatomycosis Infectious Diseases 1.18 1.05 – 1.33 0.00537 279 2810 all phecode
110.1 Dermatophytosis Infectious Diseases 1.18 1.05 – 1.33 0.00507 273 2750 all phecode
110.11 Dermatophytosis of nail Infectious Diseases 1.06 0.844 – 1.33 0.615 74 756 all phecode
110.12 Althete's foot Infectious Diseases 1.2 1.01 – 1.42 0.0349 141 1410 all phecode
112 Candidiasis Infectious Diseases 1.2 1.15 – 1.26 9.35e-17 2126 21275 all phecode
117 Mycoses Infectious Diseases 1.21 1.07 – 1.36 0.00235 272 2719 all phecode
117.4 Aspergillosis Infectious Diseases 1.12 0.96 – 1.3 0.153 165 1650 all phecode
130 Spirochetal infection Infectious Diseases 0.819 0.649 – 1.03 0.0918 80 800 all phecode
133 Arthropod-borne diseases Infectious Diseases 0.991 0.774 – 1.27 0.941 69 689 all phecode
134 Helminthiases Infectious Diseases 1.16 0.964 – 1.39 0.118 127 1267 all phecode
134.1 Intestinal helminthiases Infectious Diseases 1.1 0.902 – 1.34 0.345 106 1058 all phecode
136 Other infectious and parasitic diseases Infectious Diseases 1.22 1.06 – 1.4 0.00563 205 2050 all phecode
145 Cancer of mouth Neoplasms 1.04 0.961 – 1.13 0.32 642 6415 all phecode
145.2 Cancer of tongue Neoplasms 1.06 0.943 – 1.19 0.335 310 3096 all phecode
145.3 Cancer of major salivary glands Neoplasms 1.1 0.899 – 1.34 0.356 105 1049 all phecode
145.5 Cancer of the mouth floor Neoplasms 0.929 0.703 – 1.23 0.606 54 539 all phecode
149 Cancer of larynx, pharynx, nasal cavities Neoplasms 1.19 1.1 – 1.28 2.36e-05 635 6342 all phecode
149.1 Cancer of oropharynx Neoplasms 1.24 1.09 – 1.41 0.000758 252 2517 all phecode
149.4 Cancer of larynx Neoplasms 1.16 1.03 – 1.31 0.0126 265 2640 all phecode
149.9 Cancer of of nasal cavities Neoplasms 1.08 0.828 – 1.4 0.582 57 570 all phecode
150 Cancer of esophagus Neoplasms 1.11 1.03 – 1.19 0.00527 762 7630 all phecode
151 Cancer of stomach Neoplasms 1.14 1.05 – 1.24 0.00137 569 5696 all phecode
153 Colorectal cancer Neoplasms 1.07 1.04 – 1.1 1.77e-05 4580 45799 all phecode
153.2 Colon cancer Neoplasms 1.07 1.04 – 1.11 8.42e-05 3105 31046 all phecode
153.3
Malignant neoplasm of rectum, rectosigmoid
Malignant neoplasm of rectum, rectosigmoid junction, and anus
 Neoplasms 1.05 1.01 – 1.1 0.0195 2164 21640 all phecode
155 Cancer of liver and intrahepatic bile duct Neoplasms 1.36 1.23 – 1.5 1.07e-09 400 4008 all phecode
155.1 Malignant neoplasm of liver, primary Neoplasms 1.43 1.23 – 1.66 2.14e-06 158 1580 all phecode
157 Pancreatic cancer Neoplasms 1.29 1.19 – 1.39 7.08e-11 659 6582 all phecode
158
Neoplasm of unspecified nature of digestive
Neoplasm of unspecified nature of digestive system
 Neoplasms 1.07 1.01 – 1.14 0.0312 1063 10635 all phecode
159
Malignant neoplasm of other and ill-defined
Malignant neoplasm of other and ill-defined sites within the digestive organs and peritoneum
 Neoplasms 1.1 1.07 – 1.13 2.98e-12 5567 55694 all phecode
159.2
Malignant neoplasm of small intestine
Malignant neoplasm of small intestine, including duodenum
 Neoplasms 1.14 0.984 – 1.31 0.0828 190 1900 all phecode
159.3
Malignant neoplasm of gallbladder and
Malignant neoplasm of gallbladder and extrahepatic bile ducts
 Neoplasms 1.19 1.03 – 1.36 0.0152 205 2048 all phecode
159.4
Malignant neoplasm of retroperitoneum and
Malignant neoplasm of retroperitoneum and peritoneum
 Neoplasms 1.15 0.996 – 1.32 0.0567 193 1925 all phecode
164 Cancer of intrathoracic organs Neoplasms 1.11 0.856 – 1.43 0.437 60 600 all phecode
165 Cancer within the respiratory system Neoplasms 1.15 1.11 – 1.19 4.07e-13 2824 28235 all phecode
165.1 Cancer of bronchus; lung Neoplasms 1.15 1.1 – 1.2 2.73e-10 2230 22307 all phecode
170 Cancer of bone and connective tissue Neoplasms 0.982 0.89 – 1.08 0.723 437 4364 all phecode
170.1 Bone cancer Neoplasms 0.923 0.774 – 1.1 0.378 131 1309 all phecode
170.2 Cancer of connective tissue Neoplasms 1.03 0.919 – 1.15 0.62 331 3303 all phecode
172 Skin cancer Neoplasms 1 0.983 – 1.02 0.958 13495 134987 all phecode
172.1 Melanomas of skin, dx or hx Neoplasms 0.968 0.93 – 1.01 0.103 2681 26792 all phecode
172.11 Melanomas of skin Neoplasms 0.97 0.933 – 1.01 0.134 2713 27112 all phecode
172.2 Other non-epithelial cancer of skin Neoplasms 0.999 0.98 – 1.02 0.904 11000 110056 all phecode
172.3 Carcinoma in situ of skin Neoplasms 1.03 0.955 – 1.11 0.426 666 6656 all phecode
173 Neoplasm of uncertain behavior of skin Neoplasms 1.01 0.87 – 1.17 0.901 181 1818 all phecode
174 Breast cancer Neoplasms 1.03 1.01 – 1.05 0.00649 12686 126597 all phecode
174.1 Breast cancer [female] Neoplasms 1.03 1.01 – 1.05 0.00693 12476 124506 all phecode
174.11 Malignant neoplasm of female breast Neoplasms 1.03 1.01 – 1.05 0.00462 11757 117502 all phecode
174.3 Neoplasm of uncertain behavior of breast Neoplasms 1.23 1.01 – 1.48 0.0365 115 1148 all phecode
175 Acquired absence of breast Neoplasms 1.05 1 – 1.09 0.0363 2400 24010 all phecode
180 Cervical cancer and dysplasia Neoplasms 1.02 0.973 – 1.07 0.447 2174 21747 all phecode
180.1 Cervical cancer Neoplasms 0.921 0.812 – 1.05 0.206 272 2720 all phecode
180.3
Cervical intraepithelial neoplasia [CIN]
Cervical intraepithelial neoplasia [CIN] [Cervical dysplasia]
 Neoplasms 1.03 0.981 – 1.08 0.258 2078 20784 all phecode
182 Malignant neoplasm of uterus Neoplasms 1.13 1.06 – 1.19 5.69e-05 1282 12836 all phecode
184 Cancer of other female genital organs Neoplasms 1.09 1.03 – 1.15 0.00271 1378 13772 all phecode
184.1
Malignant neoplasm of ovary and other uterine
Malignant neoplasm of ovary and other uterine adnexa
 Neoplasms 1.08 1.01 – 1.16 0.0176 967 9667 all phecode
184.11 Malignant neoplasm of ovary Neoplasms 1.1 1.02 – 1.17 0.00812 939 9387 all phecode
184.2
Cancer of other female genital organs
Cancer of other female genital organs (excluding uterus and ovary)
 Neoplasms 1.12 0.994 – 1.26 0.0629 305 3049 all phecode
185 Cancer of prostate Neoplasms 1.01 0.988 – 1.04 0.298 5974 58812 all phecode
187 Cancer of other male genital organs Neoplasms 0.996 0.905 – 1.1 0.93 449 4485 all phecode
187.1
Malignant neoplasm of unspecified male genital
Malignant neoplasm of unspecified male genital organ
 Neoplasms 1.01 0.795 – 1.29 0.91 70 700 all phecode
187.2 Malignant neoplasm of testis Neoplasms 0.998 0.887 – 1.12 0.978 287 2868 all phecode
187.8
Neoplasm of uncertain behavior of male genital
Neoplasm of uncertain behavior of male genital organs
 Neoplasms 1.04 0.855 – 1.27 0.687 110 1098 all phecode
189
Cancer of urinary organs (incl. kidney and
Cancer of urinary organs (incl. kidney and bladder)
 Neoplasms 1.13 1.1 – 1.17 1.3e-15 4160 41604 all phecode
189.1 Cancer of kidney and renal pelvis Neoplasms 1.16 1.09 – 1.24 1.22e-06 1073 10723 all phecode
189.11 Malignant neoplasm of kidney, except pelvis Neoplasms 1.18 1.11 – 1.25 1.84e-07 1033 10324 all phecode
189.12 Malignant neoplasm of renal pelvis Neoplasms 0.979 0.771 – 1.24 0.862 66 660 all phecode
189.2 Cancer of bladder Neoplasms 1.14 1.09 – 1.18 3.12e-10 2409 24113 all phecode
189.21 Malignant neoplasm of bladder Neoplasms 1.16 1.11 – 1.21 1.69e-11 2142 21447 all phecode
189.4 Malignant neoplasm of other urinary organs Neoplasms 1.05 0.885 – 1.23 0.601 144 1439 all phecode
190 Cancer of eye Neoplasms 1.09 0.936 – 1.26 0.276 176 1758 all phecode
191
Manlignant and unknown neoplasms of brain and
Manlignant and unknown neoplasms of brain and nervous system
 Neoplasms 1.05 0.968 – 1.13 0.253 689 6879 all phecode
191.1 Cancer of brain and nervous system Neoplasms 1.03 0.947 – 1.12 0.476 566 5650 all phecode
191.11 Cancer of brain Neoplasms 1.02 0.931 – 1.11 0.698 525 5240 all phecode
193 Thyroid cancer Neoplasms 1.06 0.948 – 1.18 0.318 346 3466 all phecode
194 Cancer of other endocrine glands Neoplasms 1.1 0.892 – 1.36 0.371 95 949 all phecode
195 Cancer, suspected or other Neoplasms 1.08 1.07 – 1.1 1.56e-23 16967 165463 all phecode
195.1 Malignant neoplasm, other Neoplasms 1.08 1.06 – 1.1 3.45e-22 16267 159497 all phecode
197 Chemotherapy Neoplasms 1.13 1.11 – 1.15 2.04e-66 21433 213213 all phecode
198 Secondary malignant neoplasm Neoplasms 1.1 1.08 – 1.13 1.59e-20 9552 95503 all phecode
198.1 Secondary malignancy of lymph nodes Neoplasms 1.08 1.05 – 1.11 1.62e-07 5368 53670 all phecode
198.2 Secondary malignancy of respiratory organs Neoplasms 1.11 1.07 – 1.16 8.39e-07 2267 22670 all phecode
198.3
Secondary malignant neoplasm of digestive
Secondary malignant neoplasm of digestive systems
 Neoplasms 1.1 1.04 – 1.15 0.000458 1549 15496 all phecode
198.4 Secondary malignant neoplasm of liver Neoplasms 1.1 1.06 – 1.14 2.42e-06 2665 26648 all phecode
198.5 Secondary malignancy of brain/spine Neoplasms 1.06 0.986 – 1.13 0.12 848 8473 all phecode
198.6 Secondary malignancy of bone Neoplasms 1.1 1.05 – 1.15 1.92e-05 2161 21600 all phecode
198.7 Secondary malignant neoplasm of skin Neoplasms 1.14 0.981 – 1.32 0.0871 188 1890 all phecode
199 Neoplasm of uncertain behavior Neoplasms 1.1 1.04 – 1.16 0.000629 1432 14313 all phecode
199.4 Neurofibromatosis Neoplasms 1 0.812 – 1.23 0.996 95 950 all phecode
200 Myeloproliferative disease Neoplasms 1.18 1.11 – 1.26 3.18e-07 991 9911 all phecode
200.1 Polycythemia vera Neoplasms 1.24 1.12 – 1.37 2.47e-05 387 3867 all phecode
201 Hodgkin's disease Neoplasms 0.972 0.859 – 1.1 0.66 259 2598 all phecode
202 Cancer of other lymphoid, histiocytic tissue Neoplasms 1.05 1.01 – 1.1 0.0203 2264 22709 all phecode
202.2 Non-Hodgkins lymphoma Neoplasms 1.02 0.974 – 1.07 0.38 1802 18073 all phecode
202.21 Nodular lymphoma Neoplasms 0.972 0.875 – 1.08 0.596 363 3647 all phecode
202.24 Large cell lymphoma Neoplasms 1.07 0.981 – 1.16 0.127 581 5824 all phecode
204 Leukemia Neoplasms 1.1 1.05 – 1.15 0.000188 1660 16630 all phecode
204.1 Lymphoid leukemia Neoplasms 1.08 0.995 – 1.17 0.0675 577 5784 all phecode
204.11 Lymphoid leukemia, acute Neoplasms 1.28 0.987 – 1.66 0.0629 56 560 all phecode
204.12 Lymphoid leukemia, chronic Neoplasms 1.06 0.976 – 1.16 0.156 507 5084 all phecode
204.2 Myeloid leukemia Neoplasms 1.08 0.985 – 1.19 0.0977 462 4617 all phecode
204.21 Myeloid leukemia, acute Neoplasms 1.05 0.934 – 1.17 0.439 329 3287 all phecode
204.22 Myeloid leukemia, chronic Neoplasms 1.08 0.914 – 1.29 0.355 144 1440 all phecode
204.4 Multiple myeloma Neoplasms 1.07 0.982 – 1.16 0.121 555 5560 all phecode
208 Benign neoplasm of colon Neoplasms 1.12 1.11 – 1.14 3.43e-57 19856 191891 all phecode
210 Benign neoplasm of lip, oral cavity, and pharynx Neoplasms 1.09 1.02 – 1.17 0.00798 978 9781 all phecode
211
Benign neoplasm of other parts of digestive
Benign neoplasm of other parts of digestive system
 Neoplasms 1.13 1.09 – 1.16 9.94e-17 5243 52452 all phecode
212
Benign neoplasm of respiratory and
Benign neoplasm of respiratory and intrathoracic organs
 Neoplasms 1.12 1.01 – 1.25 0.0353 347 3466 all phecode
213 Benign neoplasm of bone and articular cartilage Neoplasms 1.04 0.927 – 1.16 0.516 318 3187 all phecode
214 Lipoma Neoplasms 1.07 1.04 – 1.09 8.32e-07 6231 62346 all phecode
214.1 Lipoma of skin and subcutaneous tissue Neoplasms 1.06 1.03 – 1.09 0.000119 4585 45872 all phecode
215
Other benign neoplasm of connective and other
Other benign neoplasm of connective and other soft tissue
 Neoplasms 1.03 0.966 – 1.09 0.4 1107 11061 all phecode
216 Benign neoplasm of skin Neoplasms 1.03 1 – 1.05 0.0301 7664 76660 all phecode
217 Vascular hamartomas and non-neoplastic nevi Neoplasms 1.08 1 – 1.17 0.0487 632 6313 all phecode
217.1 Nevus, non-neoplastic Neoplasms 1.1 1.01 – 1.19 0.0315 595 5943 all phecode
218 Benign neoplasm of uterus Neoplasms 1.07 1.05 – 1.09 9.83e-10 10023 100200 all phecode
218.1 Uterine leiomyoma Neoplasms 1.06 1.04 – 1.09 6.79e-09 10241 102376 all phecode
218.2 Other benign neoplasm of uterus Neoplasms 1.04 0.929 – 1.16 0.494 355 3548 all phecode
220 Benign neoplasm of ovary Neoplasms 1.09 1.03 – 1.15 0.00176 1445 14483 all phecode
221 Benign neoplasm of other female genital organs Neoplasms 1.08 0.943 – 1.25 0.255 220 2196 all phecode
222 Benign neoplasm of male genital organs Neoplasms 1.1 0.941 – 1.29 0.227 160 1600 all phecode
223
Benign neoplasm of kidney and other urinary
Benign neoplasm of kidney and other urinary organs
 Neoplasms 1.35 1.16 – 1.57 0.000147 173 1729 all phecode
224 Benign neoplasm of eye Neoplasms 1.17 0.981 – 1.4 0.0805 129 1299 all phecode
224.1 Benign neoplasm of eye, uveal Neoplasms 1.2 0.943 – 1.52 0.141 67 680 all phecode
225
Benign neoplasm of brain and other parts of
Benign neoplasm of brain and other parts of nervous system
 Neoplasms 1.1 1.03 – 1.19 0.00624 816 8155 all phecode
225.1
Benign neoplasm of brain, cranial nerves
Benign neoplasm of brain, cranial nerves, meninges
 Neoplasms 1.1 1.02 – 1.18 0.0121 775 7756 all phecode
225.2 Benign neoplasm of spinal cord, meninges Neoplasms 1.26 0.963 – 1.66 0.0913 59 589 all phecode
226 Benign neoplasm of thyroid glands Neoplasms 1.04 0.913 – 1.18 0.58 266 2664 all phecode
227
Benign neoplasm of other endocrine glands and
Benign neoplasm of other endocrine glands and related structures
 Neoplasms 1.16 1.08 – 1.24 2.7e-05 861 8635 all phecode
227.1 Benign neoplasm of adrenal gland Neoplasms 1.23 1.07 – 1.43 0.00425 186 1857 all phecode
227.2 Benign neoplasm of parathyroid gland Neoplasms 1.08 0.97 – 1.2 0.165 371 3709 all phecode
227.3
Benign neoplasm of pituitary gland and
Benign neoplasm of pituitary gland and craniopharyngeal duct (pouch)
 Neoplasms 1.22 1.09 – 1.36 0.000568 309 3114 all phecode
228 Hemangioma and lymphangioma, any site Neoplasms 1.06 1.01 – 1.12 0.0214 1596 15966 all phecode
229 Benign neoplasm of unspecified sites Neoplasms 1.05 1 – 1.09 0.0356 2397 23955 all phecode
240 Simple and unspecified goiter Endocrine/metabolic 1.17 1.08 – 1.28 0.00018 600 6016 all phecode
241 Nontoxic nodular goiter Endocrine/metabolic 1.1 1.04 – 1.18 0.00189 1107 11092 all phecode
241.1 Nontoxic uninodular goiter Endocrine/metabolic 1.09 0.993 – 1.2 0.0695 471 4706 all phecode
241.2 Nontoxic multinodular goiter Endocrine/metabolic 1.08 0.993 – 1.16 0.0747 676 6784 all phecode
242 Thyrotoxicosis with or without goiter Endocrine/metabolic 1.23 1.17 – 1.29 7.53e-18 1854 18531 all phecode
242.1 Graves' disease Endocrine/metabolic 1.24 1.12 – 1.36 1.23e-05 456 4553 all phecode
242.2 Toxic multinodular goiter Endocrine/metabolic 1.14 0.916 – 1.42 0.237 91 910 all phecode
242.3 Exophthalmos Endocrine/metabolic 1.39 1.18 – 1.65 9.75e-05 138 1379 all phecode
244 Hypothyroidism Endocrine/metabolic 1.2 1.18 – 1.22 1.57e-94 14590 145053 all phecode
244.1 Secondary hypothyroidism Endocrine/metabolic 1.2 1.13 – 1.27 5.52e-09 1108 11079 all phecode
244.2 Acquired hypothyroidism Endocrine/metabolic 1.3 1.07 – 1.58 0.00854 101 1010 all phecode
244.4 Hypothyroidism NOS Endocrine/metabolic 1.2 1.18 – 1.22 1.14e-91 13918 138926 all phecode
245 Thyroiditis Endocrine/metabolic 1.05 0.934 – 1.19 0.396 288 2877 all phecode
245.2 Chronic thyroiditis Endocrine/metabolic 1.1 0.959 – 1.27 0.17 218 2177 all phecode
245.21 Chronic lymphocytic thyroiditis Endocrine/metabolic 1.12 0.971 – 1.3 0.117 210 2097 all phecode
246 Other disorders of thyroid Endocrine/metabolic 1.21 1.09 – 1.34 0.000302 397 3975 all phecode
250 Diabetes mellitus Endocrine/metabolic 5.46 5.35 – 5.57 4.43e-5510 19787 186006 all phecode
250.1 Type 1 diabetes Endocrine/metabolic 3.47 3.31 – 3.63 7.3e-606 2758 27621 all phecode
250.11 Type 1 diabetes with ketoacidosis Endocrine/metabolic 2.56 2.21 – 2.97 8e-36 239 2389 all phecode
250.12 Type 1 diabetes with renal manifestations Endocrine/metabolic 4.17 3.09 – 5.63 8.98e-21 76 770 all phecode
250.13 Type 1 diabetes with ophthalmic manifestations Endocrine/metabolic 3.29 2.95 – 3.66 1.16e-102 473 4744 all phecode
250.14 Type 1 diabetes with neurological manifestations Endocrine/metabolic 4.5 3.62 – 5.59 3.64e-42 160 1610 all phecode
250.2 Type 2 diabetes Endocrine/metabolic 7.05 6.88 – 7.23 5.08e-5261 17831 170202 all phecode
250.21 Type 2 diabetes with ketoacidosis Endocrine/metabolic 5.09 3.85 – 6.74 4.23e-30 104 1050 all phecode
250.22 Type 2 diabetes with renal manifestations Endocrine/metabolic 8.09 6.3 – 10.4 1.56e-60 200 2018 all phecode
250.23 Type 2 diabetes with ophthalmic manifestations Endocrine/metabolic 7.85 7.04 – 8.74 4.76e-306 986 9907 all phecode
250.24 Type 2 diabetes with neurological manifestations Endocrine/metabolic 8.25 7.06 – 9.64 7.98e-156 503 5066 all phecode
250.4 Abnormal glucose Endocrine/metabolic 2.16 1.98 – 2.34 1.7e-74 680 6827 all phecode
250.41 Impaired fasting glucose Endocrine/metabolic 1.88 1.66 – 2.14 4.41e-22 265 2659 all phecode
250.42 Other abnormal glucose Endocrine/metabolic 2.34 2.11 – 2.61 7.79e-55 416 4178 all phecode
250.5 Glycosuria or Acetonuria Endocrine/metabolic 1.88 1.56 – 2.27 6.39e-11 131 1308 all phecode
250.6 Polyneuropathy in diabetes Endocrine/metabolic 7.18 6.02 – 8.56 3.69e-106 349 3495 all phecode
250.7 Diabetic retinopathy Endocrine/metabolic 3.45 3.24 – 3.67 4.15e-331 1329 13335 all phecode
251.1 Hypoglycemia Endocrine/metabolic 3.21 2.97 – 3.47 2.9e-194 932 9370 all phecode
252 Disorders of parathyroid gland Endocrine/metabolic 1.21 1.13 – 1.29 4.79e-08 873 8719 all phecode
252.1 Hyperparathyroidism Endocrine/metabolic 1.2 1.12 – 1.29 5.88e-07 781 7802 all phecode
252.2 Hypoparathyroidism Endocrine/metabolic 1.46 1.25 – 1.72 4.05e-06 142 1418 all phecode
253
Disorders of the pituitary gland and its
Disorders of the pituitary gland and its hypothalamic control
 Endocrine/metabolic 1.29 1.19 – 1.39 1.51e-10 681 6821 all phecode
253.1 Pituitary hyperfunction Endocrine/metabolic 1.3 1.11 – 1.51 0.000796 187 1867 all phecode
253.11 Acromegaly and gigantism Endocrine/metabolic 1.34 1.09 – 1.65 0.00534 95 949 all phecode
253.2 Pituitary hypofunction Endocrine/metabolic 1.27 1.12 – 1.43 0.000113 260 2618 all phecode
253.3 Diabetes insipidus Endocrine/metabolic 1.64 1.33 – 2.04 6.11e-06 92 919 all phecode
253.7 Other disorders of neurohypophysis Endocrine/metabolic 1.16 0.99 – 1.37 0.0663 158 1578 all phecode
255 Disorders of adrenal glands Endocrine/metabolic 1.33 1.23 – 1.44 2.35e-12 638 6374 all phecode
255.1 Adrenal hyperfunction Endocrine/metabolic 1.49 1.29 – 1.73 7.13e-08 180 1797 all phecode
255.11 Cushing's syndrome Endocrine/metabolic 1.43 1.18 – 1.74 0.000315 103 1029 all phecode
255.12 Hyperaldosteronism Endocrine/metabolic 1.56 1.25 – 1.95 7.24e-05 76 759 all phecode
255.2 Adrenal hypofunction Endocrine/metabolic 1.25 1.12 – 1.39 3.5e-05 362 3617 all phecode
255.21 Glucocorticoid deficiency Endocrine/metabolic 1.24 1.12 – 1.38 6.39e-05 361 3607 all phecode
256 Ovarian dysfunction Endocrine/metabolic 1.37 1.2 – 1.57 4.26e-06 240 2397 all phecode
256.4 Polycystic ovaries Endocrine/metabolic 1.38 1.2 – 1.6 8.5e-06 209 2088 all phecode
257 Testicular dysfunction Endocrine/metabolic 1.22 1.04 – 1.43 0.0145 160 1619 all phecode
257.1 Testicular hypofunction Endocrine/metabolic 1.3 1.1 – 1.53 0.00167 152 1539 all phecode
258 Iatrogenic endocrine disorders Endocrine/metabolic 1.2 0.986 – 1.45 0.0687 102 1020 all phecode
259 Other endocrine disorders Endocrine/metabolic 1.33 1.12 – 1.57 0.000891 149 1498 all phecode
260 Protein-calorie malnutrition Endocrine/metabolic 1.06 0.927 – 1.22 0.377 202 2018 all phecode
260.1 Cachexia Endocrine/metabolic 1.15 0.888 – 1.5 0.286 51 510 all phecode
260.6 Anorexia Endocrine/metabolic 1.14 1.07 – 1.23 0.000179 830 8317 all phecode
261 Vitamin deficiency Endocrine/metabolic 1.24 1.17 – 1.32 1.64e-13 1199 11974 all phecode
261.2 Vitamin B-complex deficiencies Endocrine/metabolic 1.25 1.16 – 1.35 1.43e-09 755 7541 all phecode
261.4 Vitamin D deficiency Endocrine/metabolic 1.28 1.16 – 1.41 5e-07 447 4462 all phecode
261.41 Rickets or osteomalacia Endocrine/metabolic 1.11 0.883 – 1.39 0.379 77 769 all phecode
262 Mineral deficiency NEC Endocrine/metabolic 1.19 1.04 – 1.35 0.0105 241 2407 all phecode
269 Proteinuria Endocrine/metabolic 1.37 1.23 – 1.51 3.75e-09 338 3378 all phecode
270
Disorders of protein plasma/amino-acid
Disorders of protein plasma/amino-acid transport and metabolism
 Endocrine/metabolic 1.07 0.955 – 1.2 0.248 303 3028 all phecode
270.3 Disorders of plasma protein metabolism Endocrine/metabolic 1.05 0.929 – 1.19 0.436 261 2608 all phecode
270.32 Paraproteinemia Endocrine/metabolic 1.18 1.03 – 1.36 0.0176 191 1910 all phecode
270.33 Amyloidosis Endocrine/metabolic 1.09 0.909 – 1.32 0.343 113 1129 all phecode
270.35 Macroglobulinemia Endocrine/metabolic 0.698 0.542 – 0.899 0.00544 69 689 all phecode
271
Disorders of carbohydrate transport and
Disorders of carbohydrate transport and metabolism
 Endocrine/metabolic 1.43 1.22 – 1.68 9.82e-06 160 1600 all phecode
271.3
Intestinal disaccharidase deficiencies and
Intestinal disaccharidase deficiencies and disaccharide malabsorption
 Endocrine/metabolic 1.33 1.12 – 1.58 0.00116 139 1391 all phecode
272 Disorders of lipoid metabolism Endocrine/metabolic 1.4 1.38 – 1.41 1.08e-758 34835 235433 all phecode
272.1 Hyperlipidemia Endocrine/metabolic 1.4 1.38 – 1.41 7.69e-759 34764 235203 all phecode
272.11 Hypercholesterolemia Endocrine/metabolic 1.4 1.38 – 1.41 3.6e-715 32324 228083 all phecode
272.12 Hyperglyceridemia Endocrine/metabolic 1.69 1.3 – 2.2 8.52e-05 58 580 all phecode
272.13 Mixed hyperlipidemia Endocrine/metabolic 1.71 1.47 – 2 7.16e-12 164 1637 all phecode
272.9 Unspecified disorder of lipoid metabolism Endocrine/metabolic 1.56 1.36 – 1.78 1.51e-10 211 2109 all phecode
274 Gout and other crystal arthropathies Endocrine/metabolic 1.36 1.31 – 1.4 2.49e-77 3724 37231 all phecode
274.1 Gout Endocrine/metabolic 1.38 1.33 – 1.43 2.77e-73 3171 31705 all phecode
274.11 Gouty arthropathy Endocrine/metabolic 1.48 1.23 – 1.77 2.13e-05 112 1119 all phecode
274.2 Crystal arthropathies Endocrine/metabolic 1.25 1.15 – 1.35 1.14e-07 613 6124 all phecode
274.21 Chondrocalcinosis Endocrine/metabolic 1.23 1.13 – 1.33 2.47e-06 558 5576 all phecode
275 Disorders of mineral metabolism Endocrine/metabolic 1.21 1.16 – 1.27 1.59e-18 2107 21070 all phecode
275.1 Disorders of iron metabolism Hematopoietic 1.11 1.02 – 1.19 0.0104 653 6535 all phecode
275.3 Disorders of magnesium metabolism Endocrine/metabolic 1.4 1.26 – 1.55 7.19e-11 375 3745 all phecode
275.5 Disorders of calcium/phosphorus metabolism Endocrine/metabolic 1.26 1.19 – 1.33 6.32e-15 1202 12019 all phecode
275.53 Disorders of phosphorus metabolism Endocrine/metabolic 1.38 1.19 – 1.61 2.21e-05 171 1717 all phecode
276
Disorders of fluid, electrolyte, and acid-base
Disorders of fluid, electrolyte, and acid-base balance
 Endocrine/metabolic 1.32 1.29 – 1.35 1.4e-123 7284 72932 all phecode
276.1 Electrolyte imbalance Endocrine/metabolic 1.31 1.27 – 1.35 1.63e-66 4086 40930 all phecode
276.11 Hyperosmolality and/or hypernatremia Endocrine/metabolic 1.51 1.33 – 1.71 1.31e-10 239 2409 all phecode
276.12 Hyposmolality and/or hyponatremia Endocrine/metabolic 1.21 1.15 – 1.27 1.75e-15 1818 18200 all phecode
276.13 Hyperpotassemia Endocrine/metabolic 1.62 1.52 – 1.72 1.52e-53 969 9728 all phecode
276.14 Hypopotassemia Endocrine/metabolic 1.21 1.15 – 1.28 1.23e-12 1424 14235 all phecode
276.4 Acid-base balance disorder Endocrine/metabolic 1.45 1.36 – 1.53 6.91e-36 1161 11629 all phecode
276.41 Acidosis Endocrine/metabolic 1.46 1.37 – 1.55 2.43e-34 1056 10577 all phecode
276.42 Alkalosis Endocrine/metabolic 1.23 1.02 – 1.48 0.0274 113 1129 all phecode
276.5 Hypovolemia Endocrine/metabolic 1.34 1.29 – 1.39 1.4e-54 2827 28265 all phecode
276.6 Fluid overload Endocrine/metabolic 1.52 1.39 – 1.67 1.18e-19 451 4535 all phecode
276.8 Polydipsia Endocrine/metabolic 1.36 1.14 – 1.62 0.000489 128 1278 all phecode
277 Other disorders of metabolism Endocrine/metabolic 1.18 1.11 – 1.27 1.03e-06 899 8977 all phecode
277.4 Disorders of bilirubin excretion Endocrine/metabolic 1.08 0.97 – 1.19 0.168 362 3613 all phecode
277.5 Other disorders of lipoid metabolism Endocrine/metabolic 1.3 1.14 – 1.47 7.62e-05 230 2298 all phecode
277.51 Lipoprotein disorders Endocrine/metabolic 1.18 0.907 – 1.53 0.22 52 520 all phecode
278 Overweight, obesity and other hyperalimentation Endocrine/metabolic 1.63 1.6 – 1.66 4.34e-536 10804 108289 all phecode
278.1 Obesity Endocrine/metabolic 1.63 1.6 – 1.67 4.87e-535 10642 106670 all phecode
278.3 Localized adiposity Endocrine/metabolic 1.31 1.04 – 1.65 0.0203 84 838 all phecode
278.4 Abnormal weight gain Endocrine/metabolic 1.9 1.5 – 2.41 1.24e-07 66 660 all phecode
279 Disorders involving the immune mechanism Endocrine/metabolic 1.03 0.905 – 1.17 0.657 250 2510 all phecode
279.1 Immunity deficiency Endocrine/metabolic 1.02 0.882 – 1.18 0.804 209 2100 all phecode
279.11 Deficiency of humoral immunity Endocrine/metabolic 0.976 0.818 – 1.17 0.79 138 1390 all phecode
279.7 Other immunological findings Endocrine/metabolic 1.07 0.946 – 1.22 0.271 248 2478 all phecode
280 Iron deficiency anemias Hematopoietic 1.25 1.22 – 1.28 9.33e-82 7610 76168 all phecode
280.1
Iron deficiency anemias, unspecified or not due
Iron deficiency anemias, unspecified or not due to blood loss
 Hematopoietic 1.26 1.23 – 1.29 8.13e-82 7311 73153 all phecode
280.2
Iron deficiency anemia secondary to blood loss
Iron deficiency anemia secondary to blood loss (chronic)
 Hematopoietic 1.15 1.05 – 1.27 0.00403 452 4541 all phecode
281 Other deficiency anemia Hematopoietic 1.29 1.21 – 1.37 8.75e-17 1112 11126 all phecode
281.1 Megaloblastic anemia Hematopoietic 1.29 1.21 – 1.37 4.13e-16 1066 10669 all phecode
281.11 Pernicious anemia Hematopoietic 1.3 1.21 – 1.4 9.52e-13 750 7514 all phecode
281.12 Other vitamin B12 deficiency anemia Hematopoietic 1.3 1.12 – 1.51 0.000664 177 1769 all phecode
281.13 Folate-deficiency anemia Hematopoietic 1.25 1.07 – 1.45 0.00401 183 1836 all phecode
281.9 Deficiency anemias Hematopoietic 1.15 0.873 – 1.52 0.319 54 538 all phecode
282 Hereditary hemolytic anemias Hematopoietic 1.28 1.09 – 1.51 0.0024 150 1499 all phecode
282.8 Other hemoglobinopathies Hematopoietic 1.26 0.969 – 1.63 0.085 56 560 all phecode
282.9 Other hereditary hemolytic anemias Hematopoietic 1.21 0.975 – 1.5 0.0844 85 849 all phecode
283 Acquired hemolytic anemias Hematopoietic 1.11 0.94 – 1.32 0.212 135 1377 all phecode
283.1 Autoimmune hemolytic anemias Hematopoietic 1.09 0.902 – 1.32 0.363 103 1059 all phecode
284 Aplastic anemia Hematopoietic 1.21 1.1 – 1.33 0.000106 435 4357 all phecode
285 Other anemias Hematopoietic 1.2 1.18 – 1.22 1.23e-84 12104 121094 all phecode
285.1 Acute posthemorrhagic anemia Hematopoietic 1.04 0.918 – 1.18 0.524 271 2707 all phecode
285.2 Anemia of chronic disease Hematopoietic 1.2 1.12 – 1.3 1.27e-06 697 6980 all phecode
285.22 Anemia in neoplastic disease Hematopoietic 1 0.906 – 1.11 0.963 414 4147 all phecode
286 Coagulation defects Hematopoietic 1.2 1.12 – 1.28 1.05e-07 921 9218 all phecode
286.1 Congenital coagulation defects Hematopoietic 1.2 1.09 – 1.32 0.000243 459 4594 all phecode
286.11 Von willebrand's disease Hematopoietic 1.12 0.909 – 1.38 0.29 96 959 all phecode
286.12
Congenital deficiency of other clotting factors
Congenital deficiency of other clotting factors (including factor VII)
 Hematopoietic 1.24 1.1 – 1.4 4e-04 294 2944 all phecode
286.13 Congenital factor VIII disorder Hematopoietic 1.44 1.11 – 1.87 0.00673 63 630 all phecode
286.5
Hemorrhagic disorder due to intrinsic
Hemorrhagic disorder due to intrinsic circulating anticoagulants
 Hematopoietic 1.32 1.08 – 1.62 0.00638 86 860 all phecode
286.7 Other and unspecified coagulation defects Hematopoietic 1.17 1.05 – 1.3 0.00339 386 3867 all phecode
287 Purpura and other hemorrhagic conditions Hematopoietic 1.17 1.11 – 1.23 5.07e-10 1652 16532 all phecode
287.1 Spontaneous ecchymoses Hematopoietic 1.23 1.03 – 1.46 0.0213 129 1290 all phecode
287.2 Allergic purpura Hematopoietic 1.26 0.945 – 1.69 0.114 51 510 all phecode
287.3 Thrombocytopenia Hematopoietic 1.17 1.11 – 1.23 1.09e-09 1553 15543 all phecode
287.31 Primary thrombocytopenia Hematopoietic 1.21 1.1 – 1.34 0.000161 419 4195 all phecode
287.32 Secondary thrombocytopenia Hematopoietic 1.09 0.874 – 1.37 0.433 75 749 all phecode
288 Diseases of white blood cells Hematopoietic 1.06 1.03 – 1.1 0.000212 3765 37672 all phecode
288.1 Decreased white blood cell count Hematopoietic 1.05 1.02 – 1.09 0.00386 3168 31704 all phecode
288.11 Neutropenia Hematopoietic 1.05 1.02 – 1.09 0.00402 3176 31784 all phecode
288.3 Eosinophilia Hematopoietic 1.03 0.81 – 1.31 0.815 71 709 all phecode
289 Other diseases of blood and blood-forming organs Hematopoietic 1.15 1.08 – 1.24 3.57e-05 862 8625 all phecode
289.3
Personal history of diseases of blood and
Personal history of diseases of blood and blood-forming organs
 Hematopoietic 1.15 1.02 – 1.29 0.0243 290 2897 all phecode
289.4 Lymphadenitis Hematopoietic 1.11 1.06 – 1.15 6.88e-07 2602 26061 all phecode
289.5 Diseases of spleen Hematopoietic 1.22 1.11 – 1.33 1.26e-05 516 5153 all phecode
289.8 Polycythemia, secondary Hematopoietic 1.2 1.07 – 1.35 0.0017 292 2917 all phecode
289.9 Abnormality of red blood cells Hematopoietic 1.55 1.25 – 1.91 5.37e-05 90 900 all phecode
290
Delirium dementia and amnestic and other
Delirium dementia and amnestic and other cognitive disorders
 Mental Disorders 1.21 1.16 – 1.26 6.74e-17 1929 19281 all phecode
290.1 Dementias Mental Disorders 1.19 1.12 – 1.26 5.23e-08 1004 10032 all phecode
290.11 Alzheimer's disease Mental Disorders 1.14 1.04 – 1.25 0.00708 431 4307 all phecode
290.16 Vascular dementia Mental Disorders 1.41 1.23 – 1.61 5.58e-07 201 2008 all phecode
290.2 Delirium due to conditions classified elsewhere Mental Disorders 1.23 1.14 – 1.33 8.54e-08 650 6501 all phecode
290.3
Other persistent mental disorders due to
Other persistent mental disorders due to conditions classified elsewhere
 Mental Disorders 0.857 0.671 – 1.09 0.217 70 709 all phecode
291
Other specified nonpsychotic and/or transient
Other specified nonpsychotic and/or transient mental disorders
 Mental Disorders 1.27 1.19 – 1.36 7.15e-12 836 8385 all phecode
291.1
Transient mental disorders due to conditions
Transient mental disorders due to conditions classified elsewhere
 Mental Disorders 1.27 1.08 – 1.51 0.005 132 1320 all phecode
291.4
Specific nonpsychotic mental disorders due to
Specific nonpsychotic mental disorders due to brain damage
 Mental Disorders 1.11 0.99 – 1.25 0.0724 286 2867 all phecode
291.8 Alteration of consciousness Mental Disorders 1.37 1.24 – 1.5 1.94e-10 436 4376 all phecode
292 Neurological disorders Mental Disorders 1.2 1.17 – 1.24 1.04e-35 4621 46260 all phecode
292.1 Aphasia/speech disturbance Mental Disorders 1.25 1.19 – 1.32 1.74e-17 1504 15074 all phecode
292.2 Mild cognitive impairment Mental Disorders 1.18 1.03 – 1.36 0.02 190 1907 all phecode
292.3 Memory loss Mental Disorders 1.12 1.03 – 1.2 0.00485 696 6978 all phecode
292.4 Altered mental status Mental Disorders 1.22 1.17 – 1.27 3.71e-20 2181 21827 all phecode
292.6 Hallucinations Mental Disorders 1.31 1.16 – 1.46 5.06e-06 307 3073 all phecode
293 Symptoms involving head and neck Mental Disorders 1.12 1.07 – 1.17 3.22e-07 2078 20779 all phecode
293.1
Swelling, mass, or lump in head and neck
Swelling, mass, or lump in head and neck [Space-occupying lesion, intracranial NOS]
 Mental Disorders 1.1 1.03 – 1.18 0.00435 901 9010 all phecode
295 Schizophrenia and other psychotic disorders Mental Disorders 1.18 1.1 – 1.27 3.72e-06 841 8446 all phecode
295.1 Schizophrenia Mental Disorders 1.14 1.05 – 1.25 0.00197 574 5766 all phecode
295.2 Paranoid disorders Mental Disorders 1.23 1.06 – 1.42 0.00715 178 1780 all phecode
295.3 Psychosis Mental Disorders 1.17 1.01 – 1.37 0.0413 169 1710 all phecode
296 Mood disorders Mental Disorders 1.24 1.22 – 1.26 2.52e-116 12372 123822 all phecode
296.1 Bipolar Mental Disorders 1.09 1.02 – 1.16 0.00652 1059 10599 all phecode
296.2 Depression Mental Disorders 1.26 1.23 – 1.28 3.35e-123 11737 117469 all phecode
296.22 Major depressive disorder Mental Disorders 1.22 1.09 – 1.36 0.000333 361 3604 all phecode
297.2 Suicide or self-inflicted injury Mental Disorders 1.18 1.05 – 1.33 0.00635 311 3070 all phecode
300 Anxiety disorders Mental Disorders 1.18 1.15 – 1.21 2.83e-40 6844 68484 all phecode
300.1 Anxiety disorder Mental Disorders 1.18 1.15 – 1.22 9.09e-38 6324 63282 all phecode
300.11 Generalized anxiety disorder Mental Disorders 1.15 0.967 – 1.36 0.114 149 1499 all phecode
300.12 Agorophobia, social phobia, and panic disorder Mental Disorders 1.15 1.06 – 1.24 0.00055 707 7065 all phecode
300.13 Phobia Mental Disorders 1.26 1.15 – 1.38 7.76e-07 501 5013 all phecode
300.3 Obsessive-compulsive disorders Mental Disorders 1.27 1.07 – 1.51 0.0068 140 1407 all phecode
300.4 Dysthymic disorder Mental Disorders 1.39 1.07 – 1.79 0.0134 53 530 all phecode
300.8 Acute reaction to stress Mental Disorders 1.21 1.01 – 1.47 0.0443 124 1238 all phecode
300.9 Posttraumatic stress disorder Mental Disorders 1.24 1.02 – 1.51 0.0338 113 1129 all phecode
301 Personality disorders Mental Disorders 1.46 1.32 – 1.63 2.24e-12 334 3338 all phecode
301.2 Antisocial/borderline personality disorder Mental Disorders 1.43 1.2 – 1.71 9.72e-05 119 1186 all phecode
302 Sexual and gender identity disorders Mental Disorders 1.31 1.16 – 1.47 5.43e-06 283 2845 all phecode
303 Psychogenic and somatoform disorders Mental Disorders 1.01 0.917 – 1.11 0.866 467 4679 all phecode
303.3 Psychogenic disorder Mental Disorders 0.937 0.838 – 1.05 0.258 350 3510 all phecode
303.4 Somatoform disorder Mental Disorders 1.32 1.1 – 1.59 0.00306 123 1229 all phecode
304 Adjustment reaction Mental Disorders 1.23 1.09 – 1.38 0.000753 293 2936 all phecode
305.2 Eating disorder Mental Disorders 1.15 0.925 – 1.43 0.207 90 900 all phecode
306 Other mental disorder Mental Disorders 1.26 1.24 – 1.27 1.05e-298 28056 230087 all phecode
306.9 Tension headache Mental Disorders 1.3 1.15 – 1.47 1.86e-05 315 3148 all phecode
313 Pervasive developmental disorders Mental Disorders 1.17 0.933 – 1.48 0.171 76 770 all phecode
313.3 Autism Mental Disorders 1.24 0.95 – 1.63 0.112 53 539 all phecode
315 Develomental delays and disorders Mental Disorders 1.23 1.11 – 1.37 0.000114 351 3517 all phecode
315.1 Learning disorder Mental Disorders 1.43 1.22 – 1.68 9.23e-06 161 1610 all phecode
315.2 Speech and language disorder Mental Disorders 1.24 1.01 – 1.52 0.0434 88 880 all phecode
316 Substance addiction and disorders Mental Disorders 1.18 1.15 – 1.22 7.2e-33 5313 53131 all phecode
316.1 Polyneuropathy due to drugs Mental Disorders 1.38 1.07 – 1.78 0.0137 60 599 all phecode
317 Alcohol-related disorders Mental Disorders 1.16 1.14 – 1.18 1.81e-57 12696 126892 all phecode
317.1 Alcoholism Mental Disorders 1.16 1.14 – 1.19 5.67e-43 8890 88923 all phecode
317.11 Alcoholic liver damage Mental Disorders 1.43 1.33 – 1.53 3.58e-24 838 8392 all phecode
318 Tobacco use disorder Mental Disorders 1.24 1.22 – 1.26 4.15e-188 19359 185465 all phecode
320 Meningitis Neurological 1.17 1.06 – 1.29 0.00148 444 4447 all phecode
323 Encephalitis Neurological 0.988 0.885 – 1.1 0.834 342 3422 all phecode
323.2 Acute (transverse) myelitis Neurological 0.869 0.677 – 1.11 0.268 74 739 all phecode
324 Other CNS infection and poliomyelitis Neurological 1.22 1.08 – 1.37 0.00103 292 2916 all phecode
327 Sleep disorders Neurological 1.23 1.16 – 1.3 7.55e-12 1164 11659 all phecode
327.3 Sleep apnea Neurological 1.48 1.44 – 1.52 1.14e-146 4428 44318 all phecode
327.4 Insomnia Neurological 1.11 0.939 – 1.3 0.229 163 1660 all phecode
327.41 Organic or persistent insomnia Neurological 1.09 0.91 – 1.3 0.355 136 1390 all phecode
331 Other cerebral degenerations Neurological 1.19 1.12 – 1.26 7.44e-09 1142 11416 all phecode
331.1 Hydrocephalus Neurological 1.07 0.974 – 1.17 0.167 502 5014 all phecode
331.9 Cerebral degeneration, unspecified Neurological 1.31 1.2 – 1.44 9.43e-09 430 4298 all phecode
332 Parkinson's disease Neurological 1.03 0.967 – 1.09 0.39 1126 11254 all phecode
333
Extrapyramidal disease and abnormal movement
Extrapyramidal disease and abnormal movement disorders
 Neurological 1.21 1.13 – 1.3 2.17e-08 894 8954 all phecode
333.1 Essential tremor Neurological 1.25 1.09 – 1.43 0.0011 216 2157 all phecode
333.2 Myoclonus Neurological 1.59 1.29 – 1.94 8.68e-06 96 958 all phecode
333.4 Torsion dystonia Neurological 1.13 0.992 – 1.29 0.0658 253 2528 all phecode
334 Degenerative disease of the spinal cord Neurological 1.21 1.15 – 1.26 7.33e-15 1812 18130 all phecode
334.1 Spinocerebellar disease Neurological 1.21 1.01 – 1.46 0.0436 117 1169 all phecode
334.2 Anterior horn cell disease Neurological 1.01 0.888 – 1.15 0.879 245 2446 all phecode
335 Multiple sclerosis Neurological 1.05 0.989 – 1.11 0.118 1340 13385 all phecode
337 Disorders of the autonomic nervous system Neurological 1.29 1.14 – 1.45 5.37e-05 266 2668 all phecode
337.1 Peripheral autonomic neuropathy Neurological 1.37 1.09 – 1.73 0.00672 72 719 all phecode
338 Pain Neurological 1.25 1.16 – 1.34 1.9e-09 768 7692 all phecode
338.1 Acute pain Neurological 1.28 1.16 – 1.42 1.01e-06 394 3937 all phecode
338.2 Chronic pain Neurological 1.22 1.1 – 1.35 0.00018 380 3817 all phecode
339 Other headache syndromes Neurological 1.17 1.14 – 1.2 5.64e-40 7819 78241 all phecode
340 Migraine Neurological 1.11 1.07 – 1.15 2.34e-07 2860 28602 all phecode
340.1 Migrain with aura Neurological 1.07 0.927 – 1.22 0.374 212 2117 all phecode
341
Other demyelinating diseases of central nervous
Other demyelinating diseases of central nervous system
 Neurological 1.09 0.951 – 1.24 0.224 252 2535 all phecode
342 Hemiplegia Neurological 1.28 1.21 – 1.35 5.07e-21 1494 14947 all phecode
343 Infantile cerebral palsy Neurological 1.09 0.917 – 1.28 0.342 145 1450 all phecode
344 Other paralytic syndromes Neurological 1.25 1.15 – 1.35 3.54e-08 658 6593 all phecode
345 Epilepsy, recurrent seizures, convulsions Neurological 1.13 1.1 – 1.17 1.44e-17 5023 50270 all phecode
345.1 Epilepsy Neurological 1.18 1.1 – 1.26 2.65e-06 866 8661 all phecode
345.11 Generalized convulsive epilepsy Neurological 1.25 1.14 – 1.38 5.77e-06 439 4385 all phecode
345.12 Partial epilepsy Neurological 1.12 0.991 – 1.26 0.0691 277 2776 all phecode
345.3 Convulsions Neurological 1.13 1.08 – 1.18 2.16e-08 2235 22339 all phecode
346.1
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of skull and head
 Neurological 1.27 1.08 – 1.51 0.00491 144 1438 all phecode
348 Other conditions of brain Neurological 1.29 1.2 – 1.38 6.59e-12 778 7808 all phecode
348.2 Cerebral edema and compression of brain Neurological 1.34 1.18 – 1.51 3.13e-06 268 2678 all phecode
348.4 Cerebral cysts Neurological 1.14 0.953 – 1.37 0.149 133 1350 all phecode
348.7 Coma Neurological 1.18 1.07 – 1.31 0.00174 358 3596 all phecode
348.8 Encephalopathy, not elsewhere classified Neurological 1.25 1.11 – 1.42 0.000283 249 2504 all phecode
348.9 Other conditions of brain, NOS Neurological 1.18 1.07 – 1.31 0.00141 390 3899 all phecode
349
Other and unspecified disorders of the nervous
Other and unspecified disorders of the nervous system
 Neurological 1.2 1.07 – 1.33 0.00107 342 3414 all phecode
350 Abnormal movement Neurological 1.25 1.2 – 1.3 1.54e-29 2671 26722 all phecode
350.1 Abnormal involuntary movements Neurological 1.2 1.12 – 1.28 9.29e-08 887 8852 all phecode
350.2 Abnormality of gait Neurological 1.26 1.2 – 1.32 5.49e-20 1596 15969 all phecode
350.3 Lack of coordination Neurological 1.35 1.22 – 1.5 1.21e-08 363 3638 all phecode
350.6 Disturbances of sensation of smell and taste Neurological 1.27 0.975 – 1.66 0.0755 54 540 all phecode
351 Other peripheral nerve disorders Neurological 1.21 1.19 – 1.23 3.29e-92 12420 124321 all phecode
352 Disorders of other cranial nerves Neurological 1.26 1.2 – 1.33 4.66e-17 1370 13706 all phecode
352.1 Trigeminal nerve disorders [CN5] Neurological 1.18 1.07 – 1.3 0.000731 463 4638 all phecode
352.2 Facial nerve disorders [CN7] Neurological 1.3 1.21 – 1.38 4.38e-14 880 8795 all phecode
353 Nerve root and plexus disorders Neurological 1.22 1.15 – 1.3 1.77e-11 1131 11319 all phecode
353.1 Nerve plexus lesions Neurological 1.05 0.868 – 1.28 0.595 114 1138 all phecode
353.2 Nerve root lesions Neurological 1.38 1.06 – 1.8 0.0169 57 570 all phecode
356 Hereditary and idiopathic peripheral neuropathy Neurological 1.05 0.893 – 1.24 0.546 152 1520 all phecode
357 Inflammatory and toxic neuropathy Neurological 1.46 1.39 – 1.54 3.46e-45 1361 13648 all phecode
358 Myoneural disorders Neurological 1.12 0.972 – 1.28 0.12 211 2109 all phecode
358.1 Myasthenia gravis Neurological 1.19 1.02 – 1.38 0.0222 192 1919 all phecode
359 Muscular dystrophies and other myopathies Neurological 1.36 1.24 – 1.49 4.52e-11 465 4646 all phecode
359.1 Muscular dystrophies Neurological 1.1 0.918 – 1.32 0.298 122 1219 all phecode
359.2 Myopathy Neurological 1.45 1.31 – 1.6 1.81e-12 360 3597 all phecode
360 Disorders of the globe Sense Organs 1.08 0.973 – 1.21 0.143 337 3367 all phecode
360.2 Progressive myopia Sense Organs 1.04 0.92 – 1.19 0.499 251 2508 all phecode
361 Retinal detachments and defects Sense Organs 1 0.965 – 1.04 0.98 3246 32453 all phecode
361.1 Retinal detachment with retinal defect Sense Organs 0.969 0.918 – 1.02 0.257 1389 13884 all phecode
361.2 Retinoschisis and retinal cysts Sense Organs 1.04 0.826 – 1.31 0.739 68 680 all phecode
362 Other retinal disorders Sense Organs 1.19 1.15 – 1.23 9.92e-27 3836 38370 all phecode
362.2
Degeneration of macula and posterior pole of
Degeneration of macula and posterior pole of retina
 Sense Organs 1.15 1.1 – 1.2 2e-10 2182 21813 all phecode
362.29 Macular degeneration (senile) of retina NOS Sense Organs 1.15 1.1 – 1.2 1.96e-10 2179 21783 all phecode
362.3 Other nondiabetic retinopathy Sense Organs 1.31 1.13 – 1.53 0.000377 161 1609 all phecode
362.31 Separation of retinal layers Sense Organs 1.04 0.85 – 1.26 0.732 99 990 all phecode
362.4 Retinal vascular changes and abnomalities Sense Organs 1.3 1.22 – 1.39 8.66e-15 848 8477 all phecode
362.6 Peripheral retinal degenerations Sense Organs 1.01 0.874 – 1.17 0.871 182 1827 all phecode
362.7 Hereditary retinal dystrophies Sense Organs 0.999 0.797 – 1.25 0.991 82 812 all phecode
362.8 Retinal hemorrhage/ischemia Sense Organs 1.1 0.918 – 1.32 0.305 116 1159 all phecode
363
Chorioretinal inflammations, scars, and other
Chorioretinal inflammations, scars, and other disorders of choroid
 Sense Organs 1.13 0.973 – 1.32 0.108 170 1699 all phecode
363.3 Chorioretinal scars Sense Organs 1.17 0.924 – 1.47 0.197 69 690 all phecode
364 Corneal opacity and other disorders of cornea Sense Organs 1.06 0.979 – 1.15 0.151 647 6485 all phecode
364.1 Corneal opacity Sense Organs 1.09 0.877 – 1.34 0.45 90 910 all phecode
364.2 Corneal edema Sense Organs 1.13 0.909 – 1.42 0.263 79 800 all phecode
364.4 Corneal degenerations Sense Organs 1.11 0.962 – 1.29 0.149 201 2017 all phecode
364.41 Keratoconus Sense Organs 0.89 0.704 – 1.13 0.334 86 869 all phecode
364.5 Corneal dystrophy Sense Organs 0.923 0.8 – 1.07 0.273 211 2109 all phecode
364.9 Cornea replaced by transplant Sense Organs 0.974 0.793 – 1.2 0.803 100 1000 all phecode
365 Glaucoma Sense Organs 1.11 1.08 – 1.15 1.34e-12 4408 44136 all phecode
365.1 Open-angle glaucoma Sense Organs 1.07 1.01 – 1.14 0.0234 1032 10346 all phecode
365.11 Primary open angle glaucoma Sense Organs 1.08 1.01 – 1.15 0.0191 1026 10287 all phecode
365.2 Primary angle-closure glaucoma Sense Organs 1.03 0.956 – 1.11 0.422 698 6996 all phecode
366 Cataract Sense Organs 1.14 1.12 – 1.15 1.08e-68 19926 168711 all phecode
366.1 Nonsenile Cataract Sense Organs 1.21 0.954 – 1.54 0.117 69 700 all phecode
366.2 Senile cataract Sense Organs 1.16 1.14 – 1.19 1.84e-40 8231 81909 all phecode
366.3 Traumatic cataract Sense Organs 0.949 0.778 – 1.16 0.61 102 1019 all phecode
367
Disorders of refraction and accommodation
Disorders of refraction and accommodation; blindness and low vision
 Sense Organs 1.1 1.05 – 1.14 1.1e-05 2408 24092 all phecode
367.1 Myopia Sense Organs 1.04 0.984 – 1.1 0.16 1251 12519 all phecode
367.2 Astigmatism Sense Organs 1.15 0.989 – 1.34 0.0691 190 1899 all phecode
367.8 Hypermetropia Sense Organs 1.09 0.962 – 1.24 0.173 253 2530 all phecode
367.9 Blindness and low vision Sense Organs 1.23 1.14 – 1.32 5.22e-08 719 7198 all phecode
368 Visual disturbances Sense Organs 1.15 1.1 – 1.19 6.53e-13 2962 29648 all phecode
368.1 Amblyopia Sense Organs 1.14 1.04 – 1.24 0.00412 532 5322 all phecode
368.2 Diplopia and disorders of binocular vision Sense Organs 1.2 1.12 – 1.29 1.37e-06 727 7288 all phecode
368.3 Anisometropia Sense Organs 1.02 0.863 – 1.2 0.836 154 1548 all phecode
368.4 Visual field defects Sense Organs 1.24 1.12 – 1.39 7.12e-05 333 3327 all phecode
368.9 Subjective visual disturbances Sense Organs 1.18 1.09 – 1.28 7.91e-05 612 6115 all phecode
369 Infection of the eye Sense Organs 1.07 0.986 – 1.17 0.105 553 5544 all phecode
369.2 Eye infection, viral Sense Organs 1.03 0.867 – 1.22 0.745 125 1257 all phecode
369.5 Conjunctivitis, infectious Sense Organs 1.1 0.957 – 1.26 0.185 213 2128 all phecode
370 Keratitis Sense Organs 1.09 0.963 – 1.23 0.177 286 2855 all phecode
370.1 Corneal ulcer Sense Organs 1.04 0.872 – 1.23 0.683 141 1408 all phecode
371 Inflammation of the eye Sense Organs 1.02 0.985 – 1.06 0.24 3045 30480 all phecode
371.1 Uveitis, noninfectious or NOS Sense Organs 1.08 0.988 – 1.19 0.0899 482 4821 all phecode
371.3 Inflammation of eyelids Sense Organs 0.993 0.952 – 1.04 0.741 2353 23555 all phecode
372 Disorders of conjunctiva Sense Organs 1.08 1 – 1.16 0.0398 760 7602 all phecode
374 Other disorders of eyelids Sense Organs 1.12 1.09 – 1.15 7.45e-17 5680 56807 all phecode
374.1 Ectropion or entropion Sense Organs 1.15 1.08 – 1.22 8.3e-06 1063 10645 all phecode
374.3 Ptosis of eyelid Sense Organs 1.13 1.07 – 1.18 9.21e-07 1825 18232 all phecode
375 Disorders of lacrimal system Sense Organs 1.09 1.05 – 1.14 4.04e-05 2204 22031 all phecode
375.2 Epiphora Sense Organs 1.1 1.03 – 1.18 0.00378 898 8969 all phecode
376 Disorders of the orbit Sense Organs 0.925 0.746 – 1.15 0.481 86 859 all phecode
377 Disorders of optic nerve and visual pathways Sense Organs 1.17 1.05 – 1.3 0.00421 361 3618 all phecode
377.1 Optic atrophy Sense Organs 1.15 0.871 – 1.53 0.319 56 570 all phecode
377.3 Optic neuritis/neuropathy Sense Organs 1.16 0.964 – 1.4 0.115 125 1249 all phecode
378
Strabismus and other disorders of binocular eye
Strabismus and other disorders of binocular eye movements
 Sense Organs 1.1 1.04 – 1.16 0.000955 1410 14116 all phecode
378.1 Strabismus (not specified as paralytic) Sense Organs 1.06 0.993 – 1.14 0.0784 909 9082 all phecode
378.2 Nystagmus and other irregular eye movements Sense Organs 1.14 0.999 – 1.31 0.052 213 2138 all phecode
378.5 Paralytic strabismus Sense Organs 1.16 1.03 – 1.31 0.0157 275 2755 all phecode
379 Other disorders of eye Sense Organs 1.16 1.12 – 1.2 1.49e-18 3703 37063 all phecode
379.2 Disorders of vitreous body Sense Organs 1.2 1.13 – 1.26 5.45e-11 1367 13665 all phecode
379.3 Aphakia and other disorders of lens Sense Organs 1.17 1.12 – 1.23 3.15e-11 1813 18134 all phecode
379.4 Anomalies of pupillary function Sense Organs 1.11 0.869 – 1.42 0.406 71 710 all phecode
379.5 Disorders of iris and ciliary body Sense Organs 1.06 0.964 – 1.18 0.215 400 4028 all phecode
379.9 Pain, swelling or discharge of eye Sense Organs 1.18 1.02 – 1.38 0.0294 169 1690 all phecode
380 Disorders of external ear Sense Organs 1.09 1.01 – 1.18 0.0323 642 6413 all phecode
380.1 Otitis externa Sense Organs 1.26 1.16 – 1.38 1.25e-07 509 5107 all phecode
380.4 Impacted cerumen Sense Organs 1.04 0.934 – 1.16 0.479 362 3614 all phecode
381 Otitis media and Eustachian tube disorders Sense Organs 1.13 1.09 – 1.19 1.25e-08 2150 21493 all phecode
381.1 Otitis media Sense Organs 1.16 1.1 – 1.22 1.9e-09 1767 17668 all phecode
381.11 Suppurative and unspecified otitis media Sense Organs 1.13 1.06 – 1.22 0.000338 852 8524 all phecode
381.2 Eustachian tube disorders Sense Organs 1.08 0.935 – 1.26 0.284 193 1929 all phecode
381.3 Mastoiditis & related conditions Sense Organs 1.17 1.01 – 1.37 0.0389 171 1709 all phecode
381.9 Otorrhea Sense Organs 1.05 0.927 – 1.18 0.465 281 2807 all phecode
382 Otalgia Sense Organs 1.1 0.976 – 1.23 0.123 308 3084 all phecode
383 Otosclerosis Sense Organs 0.932 0.827 – 1.05 0.249 309 3090 all phecode
384 Other disorders of tympanic membrane Sense Organs 1.14 1.08 – 1.21 4.49e-06 1299 12991 all phecode
384.4 Perforation of tympanic membrane Sense Organs 1.16 1.09 – 1.24 1.78e-06 1043 10432 all phecode
385 Other disorders of middle ear and mastoid Sense Organs 1.11 1.03 – 1.19 0.00482 783 7837 all phecode
385.3 Cholesteatoma Sense Organs 1.07 0.99 – 1.16 0.0867 607 6078 all phecode
385.5
Tympanosclerosis and middle ear disease related
Tympanosclerosis and middle ear disease related to otitis media
 Sense Organs 1.15 1 – 1.31 0.0446 241 2409 all phecode
386
Vertiginous syndromes and other disorders of
Vertiginous syndromes and other disorders of vestibular system
 Sense Organs 1.13 1.08 – 1.19 7.33e-07 1736 17373 all phecode
386.1 Meniere's disease Sense Organs 1.07 0.978 – 1.16 0.147 576 5768 all phecode
386.2 Peripheral or central vertigo Sense Organs 1.16 1.05 – 1.29 0.00389 377 3763 all phecode
386.3 Labyrinthitis Sense Organs 1.17 1.08 – 1.25 3.33e-05 765 7664 all phecode
386.9
Dizziness and giddiness (Light-headedness and
Dizziness and giddiness (Light-headedness and vertigo)
 Sense Organs 1.19 1.15 – 1.22 2.1e-29 4582 45806 all phecode
388 Other disorders of ear Sense Organs 1.08 0.938 – 1.25 0.272 202 2017 all phecode
389 Hearing loss Sense Organs 1.16 1.13 – 1.2 2.87e-21 4188 41944 all phecode
389.1 Sensorineural hearing loss Sense Organs 1.17 1.07 – 1.29 0.000787 456 4553 all phecode
389.2 Conductive hearing loss Sense Organs 1.1 0.995 – 1.21 0.0622 450 4497 all phecode
389.4 Tinnitus Sense Organs 1.13 1.04 – 1.24 0.00681 513 5134 all phecode
394 Rheumatic disease of the heart valves Circulatory System 1.16 1.13 – 1.2 4.75e-26 4899 48974 all phecode
394.2 Mitral valve disease Circulatory System 1.14 1.1 – 1.18 6.46e-13 2993 29922 all phecode
394.3 Aortic valve disease Circulatory System 1.2 1.13 – 1.26 2.11e-10 1282 12814 all phecode
394.7 Disease of tricuspid valve Circulatory System 1.19 1.12 – 1.26 2.45e-08 1058 10566 all phecode
395 Heart valve disorders Circulatory System 1.17 1.14 – 1.21 4.54e-24 4223 42219 all phecode
395.1 Nonrheumatic mitral valve disorders Circulatory System 1.15 1.11 – 1.2 6.64e-14 2891 28900 all phecode
395.2 Nonrheumatic aortic valve disorders Circulatory System 1.16 1.03 – 1.31 0.0124 276 2766 all phecode
395.3 Nonrheumatic tricuspid valve disorders Circulatory System 1.02 0.84 – 1.24 0.841 105 1039 all phecode
395.4 Nonrheumatic pulmonary valve disorders Circulatory System 1.17 0.959 – 1.42 0.123 97 970 all phecode
395.6 Heart valve replaced Circulatory System 1.21 1.15 – 1.27 1.42e-13 1495 14942 all phecode
396 Abnormal heart sounds Circulatory System 1.24 1.16 – 1.32 3.31e-11 1048 10468 all phecode
401 Hypertension Circulatory System 1.42 1.4 – 1.43 7.05e-1397 73956 266957 all phecode
401.1 Essential hypertension Circulatory System 1.42 1.41 – 1.43 1.18e-1395 73731 266739 all phecode
401.2 Hypertensive heart and/or renal disease Circulatory System 1.78 1.7 – 1.86 4.61e-128 1898 19031 all phecode
401.21 Hypertensive heart disease Circulatory System 1.7 1.53 – 1.89 6.69e-22 370 3699 all phecode
401.22 Hypertensive chronic kidney disease Circulatory System 1.81 1.71 – 1.9 7.72e-111 1543 15483 all phecode
401.3 Other hypertensive complications Circulatory System 1.39 1.17 – 1.65 0.000185 144 1438 all phecode
402
Elevated blood pressure reading without
Elevated blood pressure reading without diagnosis of hypertension
 Circulatory System 1.33 1.26 – 1.41 1.87e-25 1479 14786 all phecode
411 Ischemic Heart Disease Circulatory System 1.34 1.32 – 1.35 5.44e-520 31245 210714 all phecode
411.1 Unstable angina (intermediate coronary syndrome) Circulatory System 1.45 1.41 – 1.49 3.02e-156 5152 51498 all phecode
411.2 Myocardial infarction Circulatory System 1.38 1.36 – 1.41 3.6e-268 11950 112699 all phecode
411.3 Angina pectoris Circulatory System 1.41 1.39 – 1.44 2.48e-401 15888 143745 all phecode
411.4 Coronary atherosclerosis Circulatory System 1.34 1.32 – 1.36 1.71e-357 20171 154621 all phecode
411.41 Aneurysm and dissection of heart Circulatory System 1.11 1.02 – 1.19 0.0106 700 6997 all phecode
411.8
Other chronic ischemic heart disease
Other chronic ischemic heart disease, unspecified
 Circulatory System 1.46 1.43 – 1.48 1.48e-453 15290 131798 all phecode
411.9
Other acute and subacute forms of ischemic
Other acute and subacute forms of ischemic heart disease
 Circulatory System 1.38 1.3 – 1.46 1.98e-28 1218 12166 all phecode
414 Other forms of chronic heart disease Circulatory System 1.42 1.35 – 1.48 1.78e-49 1823 18228 all phecode
414.2 ASCVD Circulatory System 1.33 1.07 – 1.67 0.0115 72 719 all phecode
415 Pulmonary heart disease Circulatory System 1.13 1.1 – 1.17 6.85e-16 4476 44810 all phecode
415.11 Pulmonary embolism and infarction, acute Circulatory System 1.02 0.817 – 1.28 0.841 75 750 all phecode
415.2 Chronic pulmonary heart disease Circulatory System 1.22 1.12 – 1.32 1.38e-06 601 6002 all phecode
415.21 Primary pulmonary hypertension Circulatory System 1.19 1.09 – 1.31 0.000212 448 4475 all phecode
416 Cardiomegaly Circulatory System 1.36 1.31 – 1.41 1.12e-56 2680 26793 all phecode
418 Nonspecific chest pain Circulatory System 1.22 1.2 – 1.23 2.98e-228 28599 270106 all phecode
418.1 Precordial pain Circulatory System 1.28 1.24 – 1.32 1.69e-46 3551 35541 all phecode
420 Carditis Circulatory System 1.15 1.1 – 1.2 4.15e-10 2106 21053 all phecode
420.1 Myocarditis Circulatory System 0.977 0.813 – 1.17 0.802 127 1267 all phecode
420.2 Pericarditis Circulatory System 1.15 1.08 – 1.21 1.24e-06 1338 13371 all phecode
420.21 Acute pericarditis Circulatory System 1.21 1.06 – 1.38 0.00481 223 2227 all phecode
420.22 Chronic pericarditis Circulatory System 1.14 0.941 – 1.38 0.182 113 1129 all phecode
420.3 Endocarditis Circulatory System 1.19 1.11 – 1.28 3.17e-06 719 7194 all phecode
425 Cardiomyopathy Circulatory System 1.24 1.18 – 1.31 1.07e-14 1271 12699 all phecode
425.1 Primary/intrinsic cardiomyopathies Circulatory System 1.25 1.18 – 1.32 7.45e-15 1236 12349 all phecode
425.11 Hypertrophic obstructive cardiomyopathy Circulatory System 1.21 1.02 – 1.44 0.033 133 1329 all phecode
425.12 Other hypertrophic cardiomyopathy Circulatory System 1.09 0.933 – 1.27 0.279 163 1629 all phecode
425.8 Other cardiomyopathy Circulatory System 1.23 0.957 – 1.59 0.105 60 600 all phecode
426 Cardiac conduction disorders Circulatory System 1.27 1.24 – 1.3 1.76e-83 6910 69146 all phecode
426.2 Atrioventricular [AV] block Circulatory System 1.29 1.23 – 1.34 1.28e-31 2114 21162 all phecode
426.21 First degree AV block Circulatory System 1.34 1.26 – 1.43 1.33e-20 986 9867 all phecode
426.23 Second degree AV block Circulatory System 1.18 1.08 – 1.3 0.000284 452 4515 all phecode
426.24 Atrioventricular block, complete Circulatory System 1.31 1.21 – 1.42 7e-11 587 5868 all phecode
426.25 Other heart block Circulatory System 1.07 0.905 – 1.26 0.436 131 1318 all phecode
426.3 Bundle branch block Circulatory System 1.28 1.24 – 1.33 5.5e-46 3336 33359 all phecode
426.31 Right bundle branch block Circulatory System 1.2 1.14 – 1.26 3.61e-12 1494 14933 all phecode
426.32 Left bundle branch block Circulatory System 1.34 1.28 – 1.41 5.86e-34 1750 17503 all phecode
426.4 Anomalous atrioventricular excitation Circulatory System 1.09 0.954 – 1.25 0.202 233 2328 all phecode
426.8 Other cardiac conduction disorders Circulatory System 1.25 0.984 – 1.58 0.0684 60 600 all phecode
426.9 Cardiac pacemaker/device in situ Circulatory System 1.33 1.28 – 1.39 1.8e-46 2475 24774 all phecode
426.91 Cardiac pacemaker in situ Circulatory System 1.31 1.26 – 1.37 9.13e-39 2274 22762 all phecode
427 Cardiac dysrhythmias Circulatory System 1.17 1.15 – 1.18 1.14e-118 24207 206016 all phecode
427.1 Paroxysmal tachycardia, unspecified Circulatory System 1.15 1.11 – 1.2 4.19e-15 3199 32017 all phecode
427.11 Paroxysmal supraventricular tachycardia Circulatory System 1.13 1.09 – 1.18 3.32e-09 2344 23474 all phecode
427.12 Paroxysmal ventricular tachycardia Circulatory System 1.22 1.15 – 1.3 1.69e-09 936 9365 all phecode
427.2 Atrial fibrillation and flutter Circulatory System 1.18 1.16 – 1.2 4.48e-86 14628 133501 all phecode
427.3 Other specified cardiac dysrhythmias Circulatory System 1.2 1.15 – 1.24 4.58e-23 3228 32281 all phecode
427.4 Cardiac arrest and ventricular fibrillation Circulatory System 1.25 1.18 – 1.33 3.77e-14 1193 11915 all phecode
427.41 Ventricular fibrillation and flutter Circulatory System 1.22 1.09 – 1.36 0.00038 344 3437 all phecode
427.42 Cardiac arrest Circulatory System 1.27 1.19 – 1.35 1.17e-13 990 9890 all phecode
427.5 Arrhythmia (cardiac) NOS Circulatory System 1.11 1.04 – 1.19 0.00109 952 9541 all phecode
427.6 Premature beats Circulatory System 1.11 1.01 – 1.21 0.0234 535 5358 all phecode
427.61 Supraventricular premature beats Circulatory System 1.06 0.886 – 1.28 0.505 117 1168 all phecode
427.7 Tachycardia NOS Circulatory System 1.23 1.18 – 1.29 7.21e-21 2185 21865 all phecode
427.8 Sinoatrial node dysfunction (Bradycardia) Circulatory System 1.13 1.02 – 1.25 0.0202 402 4029 all phecode
427.9 Palpitations Circulatory System 1.15 1.11 – 1.19 3.51e-16 3811 38105 all phecode
428 Congestive heart failure; nonhypertensive Circulatory System 1.44 1.4 – 1.48 2.35e-169 5605 56018 all phecode
428.1 Congestive heart failure (CHF) NOS Circulatory System 1.6 1.53 – 1.67 2.24e-107 2111 21108 all phecode
428.2 Heart failure NOS Circulatory System 1.42 1.38 – 1.46 8.87e-123 4455 44524 all phecode
429
Ill-defined descriptions and complications of
Ill-defined descriptions and complications of heart disease
 Circulatory System 1.12 1.04 – 1.21 0.00361 716 7168 all phecode
429.1 Heart transplant/surgery Circulatory System 1.29 1.01 – 1.64 0.0432 64 639 all phecode
429.2 Abnormal function study of cardiovascular system Circulatory System 1.12 1.02 – 1.22 0.0182 522 5211 all phecode
429.3 Symptoms involving cardiovascular system Circulatory System 1.16 1 – 1.34 0.0499 196 1978 all phecode
430 Intracranial hemorrhage Circulatory System 1.09 1.04 – 1.15 0.000133 1883 18825 all phecode
430.1 Subarachnoid hemorrhage Circulatory System 1.04 0.968 – 1.11 0.288 836 8353 all phecode
430.2 Intracerebral hemorrhage Circulatory System 1.11 1.04 – 1.2 0.00346 765 7656 all phecode
430.3 Subdural hemorrhage Circulatory System 1.11 0.98 – 1.25 0.104 267 2667 all phecode
433 Cerebrovascular disease Circulatory System 1.24 1.22 – 1.27 7.16e-90 8749 87456 all phecode
433.1 Occlusion and stenosis of precerebral arteries Circulatory System 1.34 1.27 – 1.42 6.77e-25 1185 11825 all phecode
433.12 Cerebral atherosclerosis Circulatory System 1.28 1.12 – 1.45 0.00019 227 2267 all phecode
433.2 Occlusion of cerebral arteries Circulatory System 1.25 1.22 – 1.29 3.03e-48 4233 42320 all phecode
433.21
Cerebral artery occlusion, with cerebral
Cerebral artery occlusion, with cerebral infarction
 Circulatory System 1.32 1.26 – 1.39 2.26e-30 1680 16794 all phecode
433.3 Cerebral ischemia Circulatory System 1.21 1.16 – 1.25 6.4e-24 2895 28989 all phecode
433.31 Transient cerebral ischemia Circulatory System 1.2 1.15 – 1.25 3.82e-17 2135 21379 all phecode
433.5 Cerebral aneurysm Circulatory System 1.09 0.984 – 1.21 0.0998 394 3939 all phecode
433.8 Late effects of cerebrovascular disease Circulatory System 1.34 1.27 – 1.42 3.17e-25 1279 12783 all phecode
440 Atherosclerosis Circulatory System 1.53 1.46 – 1.62 6.98e-58 1380 13822 all phecode
440.1 Atherosclerosis of renal artery Circulatory System 1.33 1.11 – 1.6 0.00234 113 1129 all phecode
440.2 Atherosclerosis of the extremities Circulatory System 1.62 1.51 – 1.73 9.98e-45 805 8070 all phecode
440.9 Atherosclerosis of aorta Circulatory System 1.43 1.27 – 1.61 2.45e-09 287 2867 all phecode
441 Vascular insufficiency of intestine Circulatory System 1.23 1.14 – 1.34 2.99e-07 614 6154 all phecode
441.1 Acute vascular insufficiency of intestine Circulatory System 1.17 1.04 – 1.31 0.00917 283 2827 all phecode
442 Other aneurysm Circulatory System 1.17 1.12 – 1.22 1.88e-11 1892 18959 all phecode
442.1 Aortic aneurysm Circulatory System 1.14 1.08 – 1.2 1.12e-06 1458 14625 all phecode
442.11 Abdominal aortic aneurysm Circulatory System 1.19 1.12 – 1.27 7.14e-08 931 9341 all phecode
442.2 Aneurysm of iliac artery Circulatory System 1.24 1.03 – 1.49 0.0214 102 1019 all phecode
442.3 Aneurysm of artery of lower extremity Circulatory System 1.3 1.12 – 1.51 0.000469 169 1696 all phecode
442.4 Arterial dissection Circulatory System 1.21 0.926 – 1.59 0.161 54 549 all phecode
442.8 Aneurysm of other specified artery Circulatory System 1.19 1.03 – 1.37 0.0206 203 2028 all phecode
443 Peripheral vascular disease Circulatory System 1.49 1.45 – 1.54 8.06e-140 3921 39273 all phecode
443.1 Raynaud's syndrome Circulatory System 1.06 0.995 – 1.12 0.0716 1145 11438 all phecode
443.7
Peripheral angiopathy in diseases classified
Peripheral angiopathy in diseases classified elsewhere
 Circulatory System 3.7 3.29 – 4.17 2.12e-103 384 3878 all phecode
443.8 Other specified peripheral vascular diseases Circulatory System 1.41 1.37 – 1.46 3.61e-98 3686 36906 all phecode
443.9 Peripheral vascular disease, unspecified Circulatory System 1.58 1.53 – 1.65 4.14e-125 2579 25846 all phecode
444 Arterial embolism and thrombosis Circulatory System 1.55 1.46 – 1.65 4.65e-42 922 9251 all phecode
444.1
Arterial embolism and thrombosis of lower
Arterial embolism and thrombosis of lower extremity artery
 Circulatory System 1.68 1.55 – 1.82 2.19e-36 554 5552 all phecode
446 Polyarteritis nodosa and allied conditions Circulatory System 1.16 1.08 – 1.24 5.53e-05 822 8226 all phecode
446.4 Wegener's granulomatosis Circulatory System 1.1 0.947 – 1.27 0.219 188 1878 all phecode
446.5 Giant cell arteritis Circulatory System 1.12 1.01 – 1.24 0.0271 388 3879 all phecode
446.9 Arteritis NOS Circulatory System 1.19 1.05 – 1.36 0.00688 239 2400 all phecode
447 Other disorders of arteries and arterioles Circulatory System 1.45 1.37 – 1.53 1.16e-42 1327 13316 all phecode
447.1 Stricture of artery Circulatory System 1.55 1.45 – 1.65 1.86e-39 868 8712 all phecode
448 Disease of capillaries Circulatory System 1.04 0.878 – 1.23 0.647 142 1420 all phecode
450 Noninfectious disorders of lymphatic channels Circulatory System 1.19 1.11 – 1.29 5.59e-06 704 7034 all phecode
451 Phlebitis and thrombophlebitis Circulatory System 1.17 1.14 – 1.21 9.53e-23 3955 39683 all phecode
451.2
Phlebitis and thrombophlebitis of lower
Phlebitis and thrombophlebitis of lower extremities
 Circulatory System 1.17 1.14 – 1.21 2.34e-21 3683 36977 all phecode
452 Other venous embolism and thrombosis Circulatory System 1.2 1.11 – 1.31 1.33e-05 564 5645 all phecode
454 Varicose veins Circulatory System 1.03 1.01 – 1.05 0.00827 11180 112047 all phecode
454.1 Varicose veins of lower extremity Circulatory System 1.01 0.994 – 1.03 0.184 11503 115272 all phecode
454.11 Varicose veins of lower extremity, symptomtic Circulatory System 1.09 1.01 – 1.18 0.0346 624 6325 all phecode
455 Hemorrhoids Circulatory System 1.06 1.05 – 1.07 1.9e-17 23452 234585 all phecode
456 Chronic venous insufficiency [CVI] Circulatory System 1.09 0.945 – 1.27 0.227 184 1868 all phecode
457
Encounter for long-term (current) use of
Encounter for long-term (current) use of anticoagulants, antithrombotics, aspirin
 Circulatory System 0.869 0.709 – 1.07 0.177 97 967 all phecode
458 Hypotension Circulatory System 1.19 1.16 – 1.22 8.35e-39 5769 57772 all phecode
458.1 Orthostatic hypotension Circulatory System 1.31 1.24 – 1.39 6.01e-23 1335 13376 all phecode
458.2 Iatrogenic hypotension Circulatory System 1.29 1.13 – 1.46 0.000135 235 2348 all phecode
458.9 Hypotension NOS Circulatory System 1.19 1.15 – 1.23 4.7e-23 3494 35005 all phecode
459 Other disorders of circulatory system Circulatory System 1.23 1.22 – 1.25 6.72e-153 16268 160790 all phecode
459.1 Hemorrhage NOS Circulatory System 1.14 0.97 – 1.34 0.112 142 1420 all phecode
459.9 Circulatory disease NEC Circulatory System 1.24 1.22 – 1.26 1.2e-153 16103 159422 all phecode
464 Acute sinusitis Respiratory 1.1 0.95 – 1.27 0.209 196 1957 all phecode
465
Acute upper respiratory infections of multiple
Acute upper respiratory infections of multiple or unspecified sites
 Respiratory 1.14 1.09 – 1.19 8.77e-10 2283 22827 all phecode
465.2 Acute pharyngitis Respiratory 1.14 1.06 – 1.22 0.000364 835 8348 all phecode
465.4 Acute laryngitis and tracheitis Respiratory 1.23 1.05 – 1.44 0.00911 165 1649 all phecode
470 Septal Deviations/Turbinate Hypertrophy Respiratory 1.1 1.07 – 1.13 9.94e-10 4654 46553 all phecode
471 Nasal polyps Respiratory 1.09 1.05 – 1.13 2.67e-06 3297 32973 all phecode
472 Chronic pharyngitis and nasopharyngitis Respiratory 1.08 1.01 – 1.16 0.0179 960 9594 all phecode
473 Diseases of the larynx and vocal cords Respiratory 1.13 1.08 – 1.17 7.56e-09 2554 25548 all phecode
473.1 Chronic laryngitis Respiratory 1.17 0.964 – 1.41 0.113 104 1038 all phecode
473.3 Paralysis/spasm of vocal cords or larynx Respiratory 1.12 0.993 – 1.27 0.0648 264 2647 all phecode
473.4 Voice disturbance Respiratory 1.11 1.04 – 1.18 0.00111 1080 10789 all phecode
474 Acute and chronic tonsillitis Respiratory 1.1 1.05 – 1.16 0.000101 1772 17710 all phecode
474.1 Acute tonsillitis Respiratory 1.16 1.06 – 1.27 0.000999 549 5486 all phecode
474.2 Chronic tonsillitis and adenoiditis Respiratory 1.07 1.01 – 1.14 0.0219 1122 11199 all phecode
475 Chronic sinusitis Respiratory 1.12 1.08 – 1.17 3.62e-08 2589 25882 all phecode
476 Allergic rhinitis Respiratory 1.04 0.975 – 1.11 0.242 1055 10563 all phecode
477 Epistaxis or throat hemorrhage Respiratory 1.18 1.13 – 1.23 1.09e-15 2447 24452 all phecode
478 Throat pain Respiratory 1.01 0.905 – 1.12 0.915 377 3789 all phecode
479 Other upper respiratory disease Respiratory 1.11 1.07 – 1.14 6.3e-10 4074 40737 all phecode
480 Pneumonia Respiratory 1.21 1.19 – 1.23 1.22e-80 10336 103397 all phecode
480.1 Bacterial pneumonia Respiratory 1.2 1.18 – 1.23 1.19e-50 6637 66410 all phecode
480.11 Pneumococcal pneumonia Respiratory 1.2 1.17 – 1.23 1.88e-42 5883 58863 all phecode
480.12 Pseudomonal pneumonia Respiratory 1.49 1.23 – 1.8 4.15e-05 93 929 all phecode
480.2 Viral pneumonia Respiratory 1.15 0.908 – 1.46 0.244 72 720 all phecode
480.3 Pneumonia due to fungus (mycoses) Respiratory 1.31 1.07 – 1.6 0.00789 99 989 all phecode
480.5 Bronchopneumonia and lung abscess Respiratory 1.21 1.13 – 1.3 6.39e-08 794 7951 all phecode
481 Influenza Respiratory 1.07 0.95 – 1.19 0.28 328 3278 all phecode
483 Acute bronchitis and bronchiolitis Respiratory 1.22 1.05 – 1.41 0.00758 193 1930 all phecode
495 Asthma Respiratory 1.21 1.19 – 1.22 2.03e-184 25689 250406 all phecode
495.2 Asthma with exacerbation Respiratory 1.34 1.18 – 1.52 9.66e-06 250 2510 all phecode
496 Chronic airway obstruction Respiratory 1.3 1.28 – 1.33 7.78e-155 10424 101546 all phecode
496.1 Emphysema Respiratory 1.27 1.21 – 1.33 8.55e-23 1743 17438 all phecode
496.2 Chronic bronchitis Respiratory 1.35 1.3 – 1.4 4.74e-59 2947 29498 all phecode
496.21 Obstructive chronic bronchitis Respiratory 1.35 1.3 – 1.4 7.67e-53 2706 27081 all phecode
496.3 Bronchiectasis Respiratory 1.15 1.1 – 1.2 5.52e-09 1885 18859 all phecode
497 Bronchitis Respiratory 1.22 1.13 – 1.32 9.85e-07 626 6267 all phecode
500 Lung disease due to external agents Respiratory 1.18 1.07 – 1.3 0.00115 412 4099 all phecode
500.1 Extrinsic allergic alveolitis Respiratory 0.985 0.789 – 1.23 0.893 79 784 all phecode
500.2 Pneumoconiosis Respiratory 1.23 1.09 – 1.4 0.000781 243 2409 all phecode
501 Pneumonitis due to inhalation of food or vomitus Respiratory 1.19 1.1 – 1.29 7.78e-06 656 6557 all phecode
502 Postinflammatory pulmonary fibrosis Respiratory 1.22 1.14 – 1.3 5.25e-09 917 9193 all phecode
503 Pulmonary congestion and hypostasis Respiratory 1.57 1.44 – 1.71 7.86e-24 508 5079 all phecode
504 Other alveolar and parietoalveolar pneumonopathy Respiratory 1.27 1.14 – 1.42 2.54e-05 328 3280 all phecode
505 Other pulmonary inflamation or edema Respiratory 1.11 0.862 – 1.44 0.413 61 610 all phecode
506 Empyema and pneumothorax Respiratory 1.09 1.03 – 1.16 0.00322 1133 11362 all phecode
507 Pleurisy; pleural effusion Respiratory 1.19 1.16 – 1.22 2e-44 6419 64252 all phecode
508
Pulmonary collapse; interstitial and
Pulmonary collapse; interstitial and compensatory emphysema
 Respiratory 1.21 1.15 – 1.26 1.1e-16 1996 19947 all phecode
509 Respiratory failure, insufficiency, arrest Respiratory 1.34 1.29 – 1.39 1.17e-48 2599 26031 all phecode
509.1 Respiratory failure Respiratory 1.34 1.28 – 1.4 3.04e-39 2068 20708 all phecode
509.2 Respiratory insufficiency Respiratory 1.35 1.29 – 1.42 5.62e-37 1806 18106 all phecode
509.5 Respiratory arrest Respiratory 1.19 1.01 – 1.4 0.0338 143 1429 all phecode
509.8
Dependence on respirator [Ventilator] or
Dependence on respirator [Ventilator] or supplemental oxygen
 Respiratory 1.36 1.23 – 1.5 1.05e-09 386 3863 all phecode
510 Other diseases of lung Respiratory 1.15 1.07 – 1.24 0.000161 755 7554 all phecode
512 Other symptoms of respiratory system Respiratory 1.24 1.22 – 1.27 5.57e-91 9031 90349 all phecode
512.1 Wheezing Respiratory 1.38 1.21 – 1.58 2.31e-06 220 2196 all phecode
512.2 Painful respiration Respiratory 1.12 0.968 – 1.29 0.131 207 2075 all phecode
512.7 Shortness of breath Respiratory 1.28 1.25 – 1.32 4.39e-79 5842 58498 all phecode
512.8 Cough Respiratory 1.18 1.14 – 1.23 2.15e-18 2866 28642 all phecode
512.9 Other dyspnea Respiratory 1.22 1.14 – 1.31 3.74e-09 914 9124 all phecode
513 Respiratory abnormalities Respiratory 1.29 1.19 – 1.39 9.43e-10 611 6112 all phecode
513.3 Hypoventilation Respiratory 1.93 1.55 – 2.41 4.3e-09 83 830 all phecode
513.4 Hyperventilation Respiratory 1.29 1.14 – 1.45 4.92e-05 278 2778 all phecode
513.8 Disorders of diaphragm Respiratory 1.28 1.1 – 1.49 0.00179 153 1538 all phecode
514 Abnormal findings examination of lungs Respiratory 1.13 1.08 – 1.17 7.67e-09 2465 24673 all phecode
516 Abnormal sputum Respiratory 1.21 1.16 – 1.27 8.98e-19 2132 21335 all phecode
516.1 Hemoptysis Respiratory 1.21 1.16 – 1.26 7.22e-18 2073 20745 all phecode
519
Other diseases of respiratory system, not
Other diseases of respiratory system, not elsewhere classified
 Respiratory 1.23 1.2 – 1.25 4.64e-83 9366 93681 all phecode
519.2 Respiratory complications Respiratory 1.28 1.15 – 1.43 5.97e-06 327 3279 all phecode
519.8 Other diseases of respiratory system, NEC Respiratory 1.23 1.2 – 1.26 2.06e-81 8853 88522 all phecode
519.9
Symptoms involving respiratory system and other
Symptoms involving respiratory system and other chest symptoms
 Respiratory 0.986 0.879 – 1.11 0.811 303 3049 all phecode
520 Disorders of tooth development Digestive 1.02 0.976 – 1.07 0.349 2038 20354 all phecode
520.1 Hereditary disturbances in tooth structure Digestive 0.905 0.682 – 1.2 0.492 53 530 all phecode
520.2 Disturbances in tooth eruption Digestive 1.02 0.977 – 1.06 0.361 2356 23539 all phecode
521 Diseases of hard tissues of teeth Digestive 1.19 1.14 – 1.23 1.36e-19 3016 30245 all phecode
521.1 Dental caries Digestive 1.19 1.15 – 1.24 3.8e-20 3026 30353 all phecode
522 Diseases of pulp and periapical tissues Digestive 1.09 1.04 – 1.15 0.000475 1774 17750 all phecode
522.5 Periapical abscess Digestive 1.13 1.07 – 1.2 4.89e-05 1172 11731 all phecode
523 Gingival and periodontal diseases Digestive 1.08 1.03 – 1.14 0.00152 1681 16812 all phecode
523.1 Gingivitis Digestive 1 0.821 – 1.23 0.973 113 1127 all phecode
523.3 Periodontitis (acute or chronic) Digestive 1.03 0.972 – 1.1 0.295 1165 11650 all phecode
523.31 Acute periodontitis Digestive 1.01 0.935 – 1.1 0.739 666 6667 all phecode
523.32 Chronic periodontitis Digestive 1.06 0.976 – 1.16 0.155 560 5594 all phecode
524 Dentofacial anomalies, including malocclusion Digestive 1.04 0.93 – 1.16 0.485 331 3307 all phecode
524.3 Anomalies of tooth position/malocclusion Digestive 0.996 0.887 – 1.12 0.947 305 3046 all phecode
525
Other diseases of the teeth and supporting
Other diseases of the teeth and supporting structures
 Digestive 1.11 1.07 – 1.16 8.28e-08 2668 26728 all phecode
525.2 Atrophy of edentulous alveolar ridge Digestive 1.01 0.794 – 1.28 0.951 72 720 all phecode
526 Diseases of the jaws Digestive 1.1 1.03 – 1.17 0.00638 928 9279 all phecode
526.1 Cysts of the jaws Digestive 1.11 0.997 – 1.25 0.0561 329 3289 all phecode
526.3 Anomalies of jaw size/symmetry Digestive 1.21 0.939 – 1.55 0.143 61 610 all phecode
526.4 Temporomandibular joint disorders Digestive 1.06 0.927 – 1.21 0.405 240 2406 all phecode
526.41 Temporomandibular joint disorder, unspecified Digestive 1.08 0.943 – 1.23 0.272 233 2336 all phecode
526.5 Inflammatory conditions of jaw Digestive 1.02 0.838 – 1.24 0.853 110 1098 all phecode
526.9 Jaw disease NOS Digestive 1.13 0.993 – 1.29 0.0629 233 2329 all phecode
527 Diseases of the salivary glands Digestive 1.17 1.08 – 1.26 0.000102 694 6943 all phecode
527.1 Hypertrophy of salivary gland Digestive 1.42 1.13 – 1.77 0.00211 84 838 all phecode
527.2 Sialoadenitis Digestive 1.14 1.02 – 1.26 0.0169 365 3656 all phecode
527.7 Disturbance of salivary secretion Digestive 1.15 0.9 – 1.47 0.26 62 619 all phecode
527.8 Other specified diseases of the salivary glands Digestive 1.09 0.9 – 1.31 0.392 120 1200 all phecode
528
Diseases of the oral soft tissues, excluding
Diseases of the oral soft tissues, excluding lesions specific for gingiva and tongue
 Digestive 1.1 1.06 – 1.13 1.69e-08 3873 38741 all phecode
528.1 Stomatitis and mucositis Digestive 1.1 0.999 – 1.2 0.0514 468 4675 all phecode
528.11 Stomatitis and mucositis (ulcerative) Digestive 1.12 1.01 – 1.24 0.0327 389 3884 all phecode
528.12 Oral aphthae Digestive 1.05 0.853 – 1.3 0.629 84 840 all phecode
528.3 Cellulitis and abscess of oral soft tissues Digestive 1.12 0.965 – 1.31 0.132 179 1790 all phecode
528.4 Cysts of oral soft tissues Digestive 0.983 0.823 – 1.18 0.854 122 1219 all phecode
528.41 Cyst of the salivary gland Digestive 0.955 0.776 – 1.18 0.664 94 940 all phecode
528.5 Diseases of lips Digestive 1.05 0.973 – 1.14 0.206 681 6813 all phecode
528.6 Leukoplakia of oral mucosa Digestive 1.22 1.09 – 1.36 0.000578 308 3079 all phecode
528.7 Sialolithiasis Digestive 1.08 0.965 – 1.21 0.179 314 3138 all phecode
529 Diseases and other conditions of the tongue Digestive 1.1 1.04 – 1.17 0.00119 1232 12312 all phecode
529.1 Glossitis Digestive 1.25 1.11 – 1.4 0.000176 299 2986 all phecode
530 Diseases of esophagus Digestive 1.15 1.14 – 1.16 4.67e-131 33453 279172 all phecode
530.1 Esophagitis, GERD and related diseases Digestive 1.15 1.14 – 1.16 8.99e-124 31253 272429 all phecode
530.11 GERD Digestive 1.14 1.13 – 1.16 2.03e-85 22633 225879 all phecode
530.12 Ulcer of esophagus Digestive 1.15 1.12 – 1.18 4.8e-23 5203 52068 all phecode
530.14 Reflux esophagitis Digestive 1.14 1.11 – 1.16 1.52e-36 10444 104493 all phecode
530.2 Esophageal bleeding (varices/hemorrhage) Digestive 1.25 1.19 – 1.31 1.68e-18 1681 16808 all phecode
530.3 Stricture and stenosis of esophagus Digestive 1.07 1.02 – 1.13 0.00303 1869 18684 all phecode
530.5 Disorders of esophageal motility Digestive 1.1 1.01 – 1.19 0.0207 635 6365 all phecode
530.6 Diverticulum of esophagus, acquired Digestive 1.16 0.987 – 1.37 0.0714 153 1527 all phecode
530.7 Gastroesophageal laceration-hemorrhage syndrome Digestive 1.23 1.1 – 1.38 0.00024 341 3416 all phecode
530.9 Heartburn Digestive 1.1 1.05 – 1.15 6.78e-05 2087 20881 all phecode
531 Peptic ulcer (excl. esophageal) Digestive 1.19 1.16 – 1.21 6.31e-45 7103 71066 all phecode
531.1 Hemorrhage from gastrointestinal ulcer Digestive 1.09 1.01 – 1.18 0.0273 637 6374 all phecode
531.2 Gastric ulcer Digestive 1.19 1.15 – 1.22 2.4e-26 4091 40941 all phecode
531.3 Duodenal ulcer Digestive 1.19 1.15 – 1.24 2.52e-21 2999 30005 all phecode
531.4 Peptic ulcer, site unspecified Digestive 1.29 1.17 – 1.42 1.51e-07 427 4268 all phecode
532 Dysphagia Digestive 1.11 1.08 – 1.14 2.86e-16 6427 64329 all phecode
535 Gastritis and duodenitis Digestive 1.16 1.15 – 1.18 4.52e-131 28078 261548 all phecode
535.1 Acute gastritis Digestive 1.23 1.16 – 1.3 4.82e-12 1183 11833 all phecode
535.2 Atrophic gastritis Digestive 1.2 1.08 – 1.33 0.000456 370 3687 all phecode
535.6 Duodenitis Digestive 1.18 1.16 – 1.21 3.96e-47 7592 75928 all phecode
535.8 Other specified gastritis Digestive 1.17 1.14 – 1.19 5.15e-42 8071 80763 all phecode
535.9 Gastritis and duodenitis, NOS Digestive 1.14 0.947 – 1.38 0.165 120 1191 all phecode
536.8
Dyspepsia and other specified disorders of
Dyspepsia and other specified disorders of function of stomach
 Digestive 0.995 0.877 – 1.13 0.933 259 2576 all phecode
537 Other disorders of stomach and duodenum Digestive 1.21 1.17 – 1.25 9.98e-28 3391 33907 all phecode
540 Appendiceal conditions Digestive 1.04 1 – 1.08 0.0277 3088 30890 all phecode
540.1 Appendicitis Digestive 1.04 1 – 1.08 0.0444 2895 28963 all phecode
540.11 Acute appendicitis Digestive 1.02 0.977 – 1.06 0.394 2601 26019 all phecode
550 Abdominal hernia Digestive 1.09 1.08 – 1.1 2.22e-66 45429 282640 all phecode
550.1 Inguinal hernia Digestive 0.957 0.942 – 0.973 1.53e-07 15794 123247 all phecode
550.2 Diaphragmatic hernia Digestive 1.15 1.13 – 1.16 3.44e-102 26494 238953 all phecode
550.3 Femoral hernia Digestive 0.899 0.828 – 0.977 0.0122 651 6504 all phecode
550.4 Umbilical hernia Digestive 1.21 1.17 – 1.25 9.07e-30 3705 37072 all phecode
550.5 Ventral hernia Digestive 1.2 1.16 – 1.24 1.98e-25 3435 34338 all phecode
555
Inflammatory bowel disease and other
Inflammatory bowel disease and other gastroenteritis and colitis
 Digestive 1.12 1.09 – 1.16 1.86e-13 4444 44442 all phecode
555.1 Regional enteritis Digestive 1.14 1.09 – 1.2 1.88e-07 1734 17340 all phecode
555.2 Ulcerative colitis Digestive 1.11 1.07 – 1.16 5.11e-09 3178 31786 all phecode
555.21 Ulcerative colitis (chronic) Digestive 1.11 1.01 – 1.21 0.0256 538 5382 all phecode
556 Ulceration of the lower GI tract Digestive 1.16 1.09 – 1.24 2.85e-06 1055 10592 all phecode
556.1 Ulceration of intestine Digestive 1.15 1.06 – 1.25 0.000567 670 6714 all phecode
557 Intestinal malabsorption (non-celiac) Digestive 1.1 0.982 – 1.24 0.0992 299 2987 all phecode
557.1 Celiac disease Digestive 1.13 1.07 – 1.18 1.49e-06 1837 18388 all phecode
558 Noninfectious gastroenteritis Digestive 1.18 1.16 – 1.2 6.85e-89 15492 155105 all phecode
559 Ileostomy status Digestive 1.13 1.08 – 1.19 7.13e-07 1656 16541 all phecode
560 Intestinal obstruction without mention of hernia Digestive 1.09 1.06 – 1.13 1.65e-07 3936 39337 all phecode
560.1 Paralytic ileus Digestive 1.14 1.04 – 1.25 0.0039 523 5231 all phecode
560.2 Impaction of intestine Digestive 1.04 0.923 – 1.18 0.494 268 2671 all phecode
560.3 Peritoneal or intestinal adhesions Digestive 1.13 1.06 – 1.22 0.000532 832 8317 all phecode
560.4 Other intestinal obstruction Digestive 1.09 1.05 – 1.13 4.77e-06 3358 33550 all phecode
561 Symptoms involving digestive system Digestive 1.1 1.09 – 1.12 9.09e-32 15772 157686 all phecode
561.1 Diarrhea Digestive 1.13 1.03 – 1.24 0.0107 466 4653 all phecode
561.2 Flatulence Digestive 1.12 1.07 – 1.18 4.95e-06 1687 16859 all phecode
562 Diverticulosis and diverticulitis Digestive 1.14 1.12 – 1.15 5.56e-89 26714 211692 all phecode
562.1 Diverticulosis Digestive 1.14 1.12 – 1.15 1.84e-88 26672 211642 all phecode
563 Constipation Digestive 1.15 1.12 – 1.17 4.12e-41 10314 103140 all phecode
564 Functional digestive disorders Digestive 1.16 1.15 – 1.18 1.25e-101 21639 209949 all phecode
564.1 Irritable Bowel Syndrome Digestive 1.17 1.13 – 1.2 5.13e-27 5508 55117 all phecode
564.8
Abnormal findings on exam of gastrointestinal
Abnormal findings on exam of gastrointestinal tract/ abdominal area
 Digestive 1.15 1.09 – 1.2 1.34e-07 1645 16457 all phecode
564.9 Personal history of diseases of digestive system Digestive 1.18 1.16 – 1.2 1.75e-84 15186 151648 all phecode
565 Anal and rectal conditions Digestive 1.11 1.09 – 1.13 5.8e-33 14744 147535 all phecode
565.1 Anal and rectal polyp Digestive 1.11 1.08 – 1.14 8.97e-18 7351 73533 all phecode
567 Peritonitis and retroperitoneal infections Digestive 1.19 1.11 – 1.27 1.54e-07 929 9293 all phecode
568 Other disorders of peritoneum Digestive 1.17 1.13 – 1.22 9.35e-19 3262 32602 all phecode
568.1
Peritoneal adhesions (postoperative)
Peritoneal adhesions (postoperative) (postinfection)
 Digestive 1.17 1.13 – 1.21 5.12e-17 3101 30987 all phecode
569 Other disorders of intestine Digestive 1.13 1.1 – 1.17 2.25e-15 4192 41922 all phecode
569.1 Toxic gastroenteritis and colitis Digestive 1.24 1.06 – 1.46 0.00903 148 1479 all phecode
569.2 Gastrointestinal complications Digestive 1.01 0.924 – 1.11 0.796 486 4868 all phecode
571 Chronic liver disease and cirrhosis Digestive 1.54 1.49 – 1.6 3.25e-121 2957 29628 all phecode
571.5 Other chronic nonalcoholic liver disease Digestive 1.74 1.66 – 1.83 9.93e-112 1689 16917 all phecode
571.51 Cirrhosis of liver without mention of alcohol Digestive 1.43 1.2 – 1.71 7.22e-05 113 1139 all phecode
571.6 Primary biliary cirrhosis Digestive 1.24 1.09 – 1.4 0.00105 257 2568 all phecode
571.8
Liver abscess and sequelae of chronic liver
Liver abscess and sequelae of chronic liver disease
 Digestive 1.39 1.3 – 1.47 7.9e-25 976 9804 all phecode
571.81 Portal hypertension Digestive 1.59 1.46 – 1.73 8.07e-27 528 5285 all phecode
572 Ascites (non malignant) Digestive 1.28 1.22 – 1.35 7.6e-22 1544 15454 all phecode
573 Other disorders of liver Digestive 1.2 1.13 – 1.26 1.72e-11 1496 14982 all phecode
573.2 Liver replaced by transplant Digestive 1.53 1.25 – 1.88 4.96e-05 96 960 all phecode
573.3 Hepatomegaly Digestive 1.41 1.25 – 1.57 4.98e-09 297 2968 all phecode
573.5 Jaundice (not of newborn) Digestive 1.22 1.14 – 1.31 2.98e-09 896 8955 all phecode
573.7 Abnormal results of function study of liver Digestive 1.24 1.2 – 1.29 5.63e-36 3454 34597 all phecode
573.9 Abnormal serum enzyme levels Digestive 1.14 0.997 – 1.31 0.0548 209 2089 all phecode
574 Cholelithiasis and cholecystitis Digestive 1.23 1.21 – 1.25 3.48e-132 15607 156123 all phecode
574.1 Cholelithiasis Digestive 1.22 1.2 – 1.24 4.34e-111 13549 135537 all phecode
574.11 Cholelithiasis with acute cholecystitis Digestive 1.3 1.23 – 1.37 7.99e-23 1506 15072 all phecode
574.12 Cholelithiasis with other cholecystitis Digestive 1.23 1.2 – 1.27 6.54e-50 5429 54289 all phecode
574.2 Calculus of bile duct Digestive 1.24 1.19 – 1.29 1.51e-26 2620 26191 all phecode
574.3 Cholecystitis without cholelithiasis Digestive 1.32 1.27 – 1.38 3.61e-46 2748 27523 all phecode
575 Other biliary tract disease Digestive 1.23 1.19 – 1.27 7.7e-35 3867 38724 all phecode
575.1 Cholangitis Digestive 1.29 1.18 – 1.4 2.06e-08 495 4945 all phecode
575.2 Obstruction of bile duct Digestive 1.22 1.13 – 1.31 5.92e-08 774 7756 all phecode
575.6 Cholesterolosis of gallbladder Digestive 1.31 1.19 – 1.45 2.38e-08 458 4577 all phecode
575.7 Other disorders of gallbladder Digestive 1.26 1.2 – 1.33 4.18e-17 1408 14107 all phecode
575.8 Other disorders of biliary tract Digestive 1.21 1.14 – 1.29 1.82e-09 1036 10367 all phecode
575.9
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of biliary tract
 Digestive 1.15 1.04 – 1.28 0.00879 348 3488 all phecode
577 Diseases of pancreas Digestive 1.31 1.26 – 1.36 1.25e-42 2668 26677 all phecode
577.1 Acute pancreatitis Digestive 1.32 1.26 – 1.38 4.03e-34 1996 19962 all phecode
577.2 Chronic pancreatitis Digestive 1.61 1.48 – 1.76 1.96e-26 515 5149 all phecode
577.3 Cyst and pseudocyst of pancreas Digestive 1.38 1.24 – 1.53 1.26e-09 365 3650 all phecode
578 Gastrointestinal hemorrhage Digestive 1.1 1.09 – 1.12 2.26e-42 20626 206278 all phecode
578.1 Hematemesis Digestive 1.23 1.18 – 1.29 2.47e-19 1958 19564 all phecode
578.2 Blood in stool Digestive 1.18 1.14 – 1.23 3.7e-17 2626 26283 all phecode
578.8 Hemorrhage of rectum and anus Digestive 1.09 1.07 – 1.11 6.21e-20 13073 130745 all phecode
578.9 Hemorrhage of gastrointestinal tract Digestive 1.1 1.07 – 1.13 2.05e-10 5275 52787 all phecode
579 Other symptoms involving abdomen and pelvis Digestive 1.16 1.1 – 1.22 1.47e-08 1548 15498 all phecode
579.2 Splenomegaly Digestive 1.31 1.19 – 1.44 5.41e-08 422 4246 all phecode
579.8 Nonspecific abnormal findings in stool contents Digestive 1.08 1.03 – 1.14 0.00127 1654 16540 all phecode
580 Nephritis; nephrosis; renal sclerosis Genitourinary 1.61 1.53 – 1.69 4.39e-80 1531 15350 all phecode
580.1 Glomerulonephritis Genitourinary 1.53 1.44 – 1.63 2.91e-44 1052 10544 all phecode
580.11 Proliferative glomerulonephritis Genitourinary 1.21 0.963 – 1.53 0.102 74 738 all phecode
580.12 Non-proliferative glomerulonephritis Genitourinary 1.34 1.13 – 1.6 0.000702 135 1360 all phecode
580.14 Chronic glomerulonephritis, NOS Genitourinary 1.56 1.46 – 1.67 1.24e-40 876 8769 all phecode
580.2
Nephrotic syndrome without mention of
Nephrotic syndrome without mention of glomerulonephritis
 Genitourinary 2.11 1.92 – 2.31 8.84e-57 468 4697 all phecode
580.3
Nephritis and nephropathy without mention of
Nephritis and nephropathy without mention of glomerulonephritis
 Genitourinary 1.35 1.19 – 1.53 3.67e-06 246 2460 all phecode
580.32
Nephritis and nephropathy with pathological
Nephritis and nephropathy with pathological lesion
 Genitourinary 1.34 1.19 – 1.52 3.61e-06 253 2529 all phecode
585 Renal failure Genitourinary 1.42 1.39 – 1.46 2.44e-192 6967 69751 all phecode
585.1 Acute renal failure Genitourinary 1.43 1.39 – 1.47 2.09e-132 4527 45305 all phecode
585.2 Renal failure NOS Genitourinary 1.34 1.27 – 1.41 5.92e-30 1460 14625 all phecode
585.3 Chronic renal failure [CKD] Genitourinary 1.58 1.52 – 1.64 8.13e-123 2644 26484 all phecode
585.31 Renal dialysis Genitourinary 1.5 1.37 – 1.63 5.43e-19 496 4955 all phecode
586 Other disorders of the kidney and ureters Genitourinary 1.18 1.14 – 1.22 1.5e-20 3355 33580 all phecode
586.1 Anatomical abnormatilies of kidney and ureters Genitourinary 1.23 1.07 – 1.42 0.00445 208 2089 all phecode
586.11 Small kidney Genitourinary 1.26 1.08 – 1.46 0.00329 179 1799 all phecode
586.2 Cyst of kidney, acquired Genitourinary 1.15 1.09 – 1.22 4.7e-07 1257 12582 all phecode
586.3 Vascular disorders of kidney/hypertrophy Genitourinary 1.21 0.972 – 1.51 0.0879 80 799 all phecode
586.4 Stricture/obstruction of ureter Genitourinary 1.17 1.09 – 1.25 7e-06 910 9122 all phecode
587 Kidney replaced by transpant Genitourinary 1.22 1.1 – 1.36 0.000199 368 3683 all phecode
588 Disorders resulting from impaired renal function Genitourinary 1.31 1.08 – 1.6 0.00682 99 990 all phecode
589 Abnormal results of function study of kidney Genitourinary 1.25 1.05 – 1.5 0.0146 116 1158 all phecode
590 Pyelonephritis Genitourinary 1.25 1.19 – 1.33 1.33e-15 1328 13285 all phecode
591 Urinary tract infection Genitourinary 1.18 1.16 – 1.2 2.79e-73 12400 123937 all phecode
592 Cystitis and urethritis Genitourinary 1.13 1.08 – 1.17 3.77e-10 2966 29661 all phecode
592.1 Cystitis Genitourinary 1.13 1.09 – 1.17 2.58e-10 2904 29035 all phecode
592.11 Acute cystitis Genitourinary 0.94 0.793 – 1.11 0.476 138 1372 all phecode
592.12 Chronic cystitis Genitourinary 1.12 1.05 – 1.2 0.00108 889 8890 all phecode
592.13 Chronic interstitial cystitis Genitourinary 1.03 0.903 – 1.17 0.669 249 2486 all phecode
592.2 Urethritis and urethral syndrome Genitourinary 1.02 0.87 – 1.19 0.826 165 1662 all phecode
593 Hematuria Genitourinary 1.11 1.09 – 1.12 5.96e-35 16068 160204 all phecode
594 Urinary calculus Genitourinary 1.21 1.18 – 1.24 4.58e-49 6376 63761 all phecode
594.1 Calculus of kidney Genitourinary 1.22 1.18 – 1.27 1.28e-28 3175 31757 all phecode
594.2 Calculus of lower urinary tract Genitourinary 1.23 1.14 – 1.32 1.32e-08 776 7764 all phecode
594.3 Calculus of ureter Genitourinary 1.2 1.15 – 1.25 9.4e-19 2401 24024 all phecode
594.8 Renal colic Genitourinary 1.2 1.14 – 1.25 2.54e-15 2050 20500 all phecode
595 Hydronephrosis Genitourinary 1.18 1.13 – 1.24 3.97e-13 1936 19395 all phecode
596 Other disorders of bladder Genitourinary 1.09 1.07 – 1.11 3.34e-17 9771 97778 all phecode
596.1 Bladder neck obstruction Genitourinary 1.04 0.994 – 1.09 0.086 1969 19690 all phecode
596.5 Functional disorders of bladder Genitourinary 1.11 1.05 – 1.16 5.51e-05 1658 16572 all phecode
597 Other disorders of urethra and urinary tract Genitourinary 1.14 1.1 – 1.17 8.12e-15 3913 39135 all phecode
597.1 Urethral stricture (not specified as infectious) Genitourinary 1.14 1.1 – 1.18 4.09e-14 3317 33137 all phecode
597.2 Urinary complications NEC Genitourinary 1.2 0.97 – 1.49 0.0918 78 778 all phecode
598 Abnormal findings on examination of urine Genitourinary 1.07 1.03 – 1.11 0.000112 3528 35302 all phecode
598.9
Other nonspecific findings on examination of
Other nonspecific findings on examination of urine
 Genitourinary 1.09 0.97 – 1.22 0.151 304 3035 all phecode
599 Other symptoms/disorders or the urinary system Genitourinary 1.13 1.12 – 1.15 1.18e-60 18428 184311 all phecode
599.1 Urinary obstruction Genitourinary 1.14 0.973 – 1.33 0.107 166 1670 all phecode
599.2 Retention of urine Genitourinary 1.13 1.1 – 1.16 1.23e-22 6718 67168 all phecode
599.3 Dysuria Genitourinary 1.14 1.07 – 1.2 1.76e-05 1196 11967 all phecode
599.4 Urinary incontinence Genitourinary 1.16 1.14 – 1.19 1.48e-41 8748 87477 all phecode
599.5 Frequency of urination and polyuria Genitourinary 1.11 1.08 – 1.15 3.69e-11 4018 40144 all phecode
599.6 Oliguria and anuria Genitourinary 1.25 1.04 – 1.5 0.0175 105 1059 all phecode
599.8 Other symptoms involving urinary system Genitourinary 1.1 0.846 – 1.42 0.489 62 620 all phecode
599.9 Other abnormality of urination Genitourinary 1.12 1.07 – 1.17 6.87e-07 1913 19151 all phecode
600 Hyperplasia of prostate Genitourinary 1.07 1.05 – 1.09 3.56e-11 11093 87892 all phecode
601 Inflammatory diseases of prostate Genitourinary 1.11 1.07 – 1.16 1.3e-06 2081 20818 all phecode
601.1 Prostatitis Genitourinary 1.06 1.01 – 1.11 0.0296 1563 15644 all phecode
601.11 Acute prostatitis Genitourinary 1.07 0.939 – 1.22 0.316 234 2358 all phecode
601.12 Chronic prostatitis Genitourinary 1.02 0.958 – 1.09 0.5 910 9089 all phecode
601.3 Orchitis and epididymitis Genitourinary 0.907 0.697 – 1.18 0.466 59 588 all phecode
601.4 Balanoposthitis Genitourinary 1.31 1.17 – 1.47 2.33e-06 287 2864 all phecode
601.8
Other inflammatory disorders of male genital
Other inflammatory disorders of male genital organs
 Genitourinary 1.25 1.11 – 1.4 0.000161 303 3019 all phecode
602 Other disorders of prostate Genitourinary 1.06 1.01 – 1.12 0.0246 1341 13408 all phecode
603 Other disorders of testis Genitourinary 1.15 1.1 – 1.2 1.96e-10 2150 21512 all phecode
603.1 Hydrocele Genitourinary 1.14 1.08 – 1.21 1.4e-06 1339 13402 all phecode
604 Disorders of penis Genitourinary 1.19 1.15 – 1.24 5.74e-24 3280 32779 all phecode
604.1 Redundant prepuce and phimosis/BXO Genitourinary 1.21 1.17 – 1.26 1.57e-23 2719 27172 all phecode
605 Erectile dysfunction [ED] Genitourinary 1.28 1.14 – 1.44 2.34e-05 278 2800 all phecode
608 Other disorders of male genital organs Genitourinary 1.04 1 – 1.08 0.0483 2822 28236 all phecode
609 Male infertility and abnormal spermatozoa Genitourinary 1.06 0.922 – 1.21 0.423 214 2138 all phecode
609.1 Infertility, male Genitourinary 0.905 0.7 – 1.17 0.445 63 638 all phecode
609.2 Abnormal spermatozoa Genitourinary 1.07 0.919 – 1.25 0.377 169 1698 all phecode
610 Benign mammary dysplasias Genitourinary 1 0.958 – 1.04 0.989 2482 24809 all phecode
610.1 Cystic mastopathy Genitourinary 0.939 0.875 – 1.01 0.0751 925 9250 all phecode
610.2 Fibroadenosis of breast Genitourinary 1.01 0.897 – 1.14 0.869 306 3057 all phecode
610.3 Fibrosclerosis of breast Genitourinary 1.01 0.899 – 1.14 0.818 302 3018 all phecode
610.4 Benign neoplasm of breast Genitourinary 0.986 0.932 – 1.04 0.635 1388 13865 all phecode
610.8 Other specified benign mammary dysplasias Genitourinary 1.15 1.06 – 1.24 0.000724 696 6954 all phecode
611 Abnormal findings on mammogram or breast exam Genitourinary 1.02 0.969 – 1.08 0.428 1574 15731 all phecode
611.1 Abnormal mammogram Genitourinary 1.06 0.804 – 1.38 0.699 57 569 all phecode
611.3 Lump or mass in breast Genitourinary 1.03 0.973 – 1.08 0.332 1522 15213 all phecode
612
Breast conditions, congenital or relating to
Breast conditions, congenital or relating to hormones
 Genitourinary 1.19 1.11 – 1.27 1.17e-06 887 8871 all phecode
612.2 Hypertrophy of breast (Gynecomastia) Genitourinary 1.18 1.1 – 1.26 5.26e-06 849 8490 all phecode
612.3 Congenital anomalies of breast Genitourinary 1.09 0.858 – 1.39 0.474 72 719 all phecode
613 Other nonmalignant breast conditions Genitourinary 1.1 1.05 – 1.16 0.000186 1651 16519 all phecode
613.1 Inflammatory disease of breast Genitourinary 1.1 1.01 – 1.18 0.0204 720 7210 all phecode
613.5 Mastodynia Genitourinary 1.28 1.01 – 1.61 0.0389 77 768 all phecode
613.7 Other signs and symptoms in breast Genitourinary 0.97 0.896 – 1.05 0.458 702 7013 all phecode
613.8 Other specified disorders of breast Genitourinary 1.08 0.962 – 1.21 0.19 327 3278 all phecode
613.9 Breast disorder NOS Genitourinary 1.09 0.943 – 1.26 0.247 207 2069 all phecode
614 Inflammatory diseases of female pelvic organs Genitourinary 1.09 1.06 – 1.12 1.17e-09 5711 57118 all phecode
614.1
Pelvic peritoneal adhesions, female
Pelvic peritoneal adhesions, female (postoperative) (postinfection)
 Genitourinary 1.14 1.09 – 1.18 3.18e-09 2538 25363 all phecode
614.3 Pelvic inflammatory disease (PID) Genitourinary 1.1 1.02 – 1.18 0.0103 830 8308 all phecode
614.31 Acute inflammatory pelvic disease Genitourinary 1.33 1.02 – 1.73 0.0366 61 608 all phecode
614.32 Chronic inflammatory pelvic disease Genitourinary 1.1 0.995 – 1.22 0.0622 422 4221 all phecode
614.33 Pelvic inflammatory disease, NOS Genitourinary 1.03 0.92 – 1.15 0.624 351 3510 all phecode
614.4 Inflammatory diseases of uterus, except cervix Genitourinary 1.06 0.936 – 1.2 0.359 277 2775 all phecode
614.5
Inflammatory disease of cervix, vagina, and
Inflammatory disease of cervix, vagina, and vulva
 Genitourinary 1.05 1.01 – 1.1 0.0164 2601 26023 all phecode
614.51 Cervicitis and endocervicitis Genitourinary 1.02 0.958 – 1.08 0.61 1318 13189 all phecode
614.52 Vaginitis and vulvovaginitis Genitourinary 1.18 1.07 – 1.31 0.00112 428 4273 all phecode
614.53 Cyst or abscess of Bartholin's gland Genitourinary 0.95 0.88 – 1.03 0.189 755 7574 all phecode
614.54 Abscess or ulceration of vulva Genitourinary 1.24 1.09 – 1.41 0.000812 274 2737 all phecode
615 Endometriosis Genitourinary 1.12 1.08 – 1.15 1.26e-10 4029 40284 all phecode
617
Disorders secondary to childbirth, surgery
Disorders secondary to childbirth, surgery, trauma
 Genitourinary 1.06 0.942 – 1.19 0.339 304 3037 all phecode
618 Genital prolapse Genitourinary 1.09 1.07 – 1.11 1.16e-17 11689 116878 all phecode
618.1 Prolapse of vaginal walls Genitourinary 1.1 1.08 – 1.13 7.67e-16 7392 73940 all phecode
618.2 Uterine/Uterovaginal prolapse Genitourinary 1.07 1.04 – 1.1 9.11e-06 5393 53918 all phecode
618.5 Prolapse of vaginal vault after hysterectomy Genitourinary 1.14 1.04 – 1.24 0.00685 512 5125 all phecode
618.6 Vaginal enterocele, congenital or acquired Genitourinary 1.13 1.04 – 1.22 0.00274 680 6794 all phecode
619 Noninflammatory female genital disorders Genitourinary 1.07 1.05 – 1.1 1.03e-09 8726 87297 all phecode
619.1
Noninflammatory disorders of ovary, fallopian
Noninflammatory disorders of ovary, fallopian tube, and broad ligament
 Genitourinary 1.11 1.03 – 1.2 0.00597 729 7284 all phecode
619.2 Disorders of uterus, NEC Genitourinary 1.06 1.02 – 1.1 0.00213 3324 33273 all phecode
619.3 Noninflammatory disorders of cervix Genitourinary 1.07 1.03 – 1.11 0.000791 2860 28608 all phecode
619.4 Noninflammatory disorders of vagina Genitourinary 1.03 0.982 – 1.08 0.218 1768 17669 all phecode
619.5 Noninflammatory disorders of vulva and perineum Genitourinary 1.05 0.992 – 1.11 0.0919 1350 13489 all phecode
620 Dysplasia of female genital organs Genitourinary 1.19 0.942 – 1.5 0.147 72 720 all phecode
621 Endometrial hyperplasia Genitourinary 1.18 1.11 – 1.26 8.05e-08 1129 11294 all phecode
622 Polyp of female genital organs Genitourinary 1.06 1.04 – 1.08 1.37e-08 10480 104803 all phecode
622.1 Polyp of corpus uteri Genitourinary 1.07 1.04 – 1.09 4.11e-08 7857 78601 all phecode
622.2 Mucous polyp of cervix Genitourinary 1 0.969 – 1.04 0.809 3442 34387 all phecode
623 Hypertrophy of female genital organs Genitourinary 1.07 1.01 – 1.14 0.0252 1268 12684 all phecode
624 Symptoms involving female genital tract Genitourinary 1.05 0.976 – 1.13 0.193 797 7961 all phecode
624.1 Dystrophy of female genital tract Genitourinary 1.11 0.974 – 1.27 0.116 237 2365 all phecode
624.2 Atrophy of female genital tract Genitourinary 1.07 0.968 – 1.18 0.186 440 4398 all phecode
624.9 stress incontinence, female Genitourinary 1.16 1.13 – 1.2 4.27e-28 5865 58634 all phecode
625
Pain and other symptoms associated with female
Pain and other symptoms associated with female genital organs
 Genitourinary 1.05 1.01 – 1.09 0.0155 2876 28740 all phecode
625.1 Dyspareunia Genitourinary 1.01 0.953 – 1.08 0.67 1188 11891 all phecode
626
Disorders of menstruation and other abnormal
Disorders of menstruation and other abnormal bleeding from female genital tract
 Genitourinary 1.1 1.08 – 1.11 1.53e-25 16168 115018 all phecode
626.1 Irregular menstrual cycle/bleeding Genitourinary 1.1 1.08 – 1.12 4.42e-27 14110 109918 all phecode
626.11 Absent or infrequent menstruation Genitourinary 1.12 0.919 – 1.37 0.259 109 1099 all phecode
626.12 Excessive or frequent menstruation Genitourinary 1.11 1.09 – 1.14 1.6e-22 9727 91749 all phecode
626.13 Irregular menstrual cycle Genitourinary 1.06 1.01 – 1.11 0.024 1985 19829 all phecode
626.14 Irregular menstrual bleeding Genitourinary 1.1 1.06 – 1.14 7.64e-08 3804 38021 all phecode
626.2 Dysmenorrhea Genitourinary 1.15 1.09 – 1.21 4.05e-08 1778 17767 all phecode
626.4 Premenstrual tension syndromes Genitourinary 1.12 0.949 – 1.33 0.176 159 1587 all phecode
626.8 Infertility, female Genitourinary 0.921 0.868 – 0.977 0.00603 1362 13613 all phecode
627 Menopausal and postmenopausal disorders Genitourinary 1.08 1.06 – 1.1 3.05e-13 10392 103948 all phecode
627.1 Postmenopausal bleeding Genitourinary 1.08 1.06 – 1.1 2.54e-12 9042 90439 all phecode
627.2 Symptomatic menopause Genitourinary 1.19 1.02 – 1.39 0.0276 183 1826 all phecode
627.3 Postmenopausal atrophic vaginitis Genitourinary 0.993 0.934 – 1.06 0.834 1111 11115 all phecode
627.4 Premenopausal menorrhagia Genitourinary 1.08 0.963 – 1.22 0.184 310 3097 all phecode
628 Ovarian cyst Genitourinary 1.11 1.08 – 1.15 1.34e-11 4747 47482 all phecode
634 Miscarriage; stillbirth Pregnancy Complications 0.955 0.926 – 0.985 0.00309 5218 36422 all phecode
634.1 Missed abortion/Hydatidiform mole Pregnancy Complications 0.927 0.871 – 0.988 0.0198 1136 11300 all phecode
634.3 Ectopic pregnancy Pregnancy Complications 0.959 0.853 – 1.08 0.48 331 3305 all phecode
635
Hemorrhage during pregnancy; childbirth and
Hemorrhage during pregnancy; childbirth and postpartum
 Pregnancy Complications 0.947 0.902 – 0.994 0.0264 1974 17372 all phecode
635.2
Antepartum hemorrhage, abruptio placentae, and
Antepartum hemorrhage, abruptio placentae, and placenta previa
 Pregnancy Complications 0.904 0.84 – 0.973 0.00697 866 8614 all phecode
635.3 Placenta previa and abruptio placenta Pregnancy Complications 0.949 0.893 – 1.01 0.085 1270 12306 all phecode
636
Early or threatened labor; hemorrhage in early
Early or threatened labor; hemorrhage in early pregnancy
 Pregnancy Complications 0.981 0.938 – 1.03 0.398 2347 19972 all phecode
636.2 Early onset of delivery Pregnancy Complications 0.949 0.869 – 1.03 0.235 617 6144 all phecode
636.3 Hemorrhage in early pregnancy Pregnancy Complications 0.978 0.916 – 1.04 0.501 1082 10766 all phecode
638 Other high-risk pregnancy Pregnancy Complications 0.83 0.64 – 1.08 0.16 70 700 all phecode
642
Hypertension complicating pregnancy
Hypertension complicating pregnancy, childbirth, and the puerperium
 Pregnancy Complications 1.05 0.987 – 1.12 0.117 1110 11074 all phecode
642.1 Preeclampsia and eclampsia Pregnancy Complications 0.991 0.879 – 1.12 0.884 307 3058 all phecode
643 Excessive vomiting in pregnancy Pregnancy Complications 1.06 0.914 – 1.22 0.458 215 2149 all phecode
643.1 Hyperemesis gravidarum Pregnancy Complications 1.02 0.856 – 1.21 0.856 153 1525 all phecode
645 Late pregnancy and failed induction Pregnancy Complications 0.941 0.886 – 1 0.0518 1250 12450 all phecode
646 Other complications of pregnancy NEC Pregnancy Complications 0.99 0.945 – 1.04 0.661 2228 20847 all phecode
647
Infectious and parasitic complications
Infectious and parasitic complications affecting pregnancy
 Pregnancy Complications 1.07 0.832 – 1.39 0.582 68 679 all phecode
647.1
Infections of genitourinary tract during
Infections of genitourinary tract during pregnancy
 Pregnancy Complications 0.982 0.86 – 1.12 0.794 275 2748 all phecode
649
Other conditions or status of the mother
Other conditions or status of the mother complicating pregnancy, childbirth, or the puerperium
 Pregnancy Complications 0.859 0.701 – 1.05 0.141 113 1129 all phecode
649.1
Diabetes or abnormal glucose tolerance
Diabetes or abnormal glucose tolerance complicating pregnancy
 Pregnancy Complications 1.62 1.39 – 1.89 6.06e-10 193 1922 all phecode
650 Normal delivery Pregnancy Complications 0.921 0.877 – 0.968 0.00111 1922 18973 all phecode
651 Multiple gestation Pregnancy Complications 0.974 0.867 – 1.09 0.662 346 3454 all phecode
652
Malposition and malpresentation of fetus or
Malposition and malpresentation of fetus or obstruction
 Pregnancy Complications 0.963 0.914 – 1.01 0.159 1716 16521 all phecode
653
Problems associated with amniotic cavity and
Problems associated with amniotic cavity and membranes
 Pregnancy Complications 0.951 0.897 – 1.01 0.0859 1401 13649 all phecode
654
Other and unspecified complications of birth
Other and unspecified complications of birth; puerperium affecting management of mother
 Pregnancy Complications 0.999 0.778 – 1.28 0.995 74 739 all phecode
655
Known or suspected fetal abnormality affecting
Known or suspected fetal abnormality affecting management of mother
 Pregnancy Complications 0.949 0.917 – 0.982 0.00247 4306 29454 all phecode
656 Other perinatal conditions of fetus or newborn Pregnancy Complications 0.893 0.729 – 1.09 0.274 109 1080 all phecode
661 Fetal distress and abnormal forces of labor Pregnancy Complications 0.906 0.865 – 0.949 2.83e-05 2265 18397 all phecode
663
Umbilical cord complications during labor and
Umbilical cord complications during labor and delivery
 Pregnancy Complications 0.964 0.878 – 1.06 0.436 532 5316 all phecode
665 Obstetrical/birth trauma Pregnancy Complications 0.911 0.883 – 0.94 4.74e-09 5313 29472 all phecode
669 Complications of labor and delivery NEC Pregnancy Complications 0.928 0.888 – 0.969 0.000687 2552 21174 all phecode
671
Venous/cerebrovascular complications embolism
Venous/cerebrovascular complications embolism in pregnancy and the puerperium
 Pregnancy Complications 1.04 0.879 – 1.23 0.653 164 1628 all phecode
674 Other complications of the puerperium NEC Pregnancy Complications 1.17 1.02 – 1.33 0.022 262 2605 all phecode
676
Other disorders of the breast associated with
Other disorders of the breast associated with childbirth and disorders of lactation
 Pregnancy Complications 0.999 0.761 – 1.31 0.992 63 624 all phecode
679 Complications of in utero procedures Dermatologic 0.725 0.545 – 0.964 0.027 53 530 all phecode
681 Superficial cellulitis and abscess Dermatologic 1.28 1.25 – 1.31 3.14e-93 7200 72225 all phecode
681.1 Cellulitis and abscess of fingers/toes Dermatologic 1.27 1.17 – 1.38 2.13e-08 563 5647 all phecode
681.2 Cellulitis and abscess of face/neck Dermatologic 1.19 1.09 – 1.3 0.000116 520 5208 all phecode
681.3 Cellulitis and abscess of arm/hand Dermatologic 1.3 1.26 – 1.33 2.46e-81 5481 55014 all phecode
681.5 Cellulitis and abscess of leg, except foot Dermatologic 1.3 1.27 – 1.34 1.16e-82 5487 55074 all phecode
681.6 Cellulitis and abscess of foot, toe Dermatologic 1.3 1.27 – 1.34 2.22e-82 5444 54643 all phecode
681.7 Cellulitis and abscess of trunk Dermatologic 1.25 1.15 – 1.36 1.77e-07 597 5987 all phecode
686
Other local infections of skin and subcutaneous
Other local infections of skin and subcutaneous tissue
 Dermatologic 1.35 1.28 – 1.42 1.11e-26 1337 13427 all phecode
686.1 Carbuncle and furuncle Dermatologic 1.29 1.24 – 1.35 3.61e-33 2284 22925 all phecode
686.3 Pilonidal cyst Dermatologic 1.14 1.04 – 1.24 0.00316 583 5837 all phecode
686.4 Pyogenic granuloma Dermatologic 1.14 1.02 – 1.27 0.0163 362 3615 all phecode
687 Symptoms affecting skin Dermatologic 1.11 1.01 – 1.21 0.0246 548 5508 all phecode
687.1 Rash and other nonspecific skin eruption Dermatologic 1.13 1.08 – 1.18 1.09e-07 2146 21470 all phecode
687.2 Localized superficial swelling, mass, or lump Dermatologic 1.09 0.964 – 1.23 0.171 283 2839 all phecode
687.3 Changes in skin texture Dermatologic 0.852 0.693 – 1.05 0.129 106 1070 all phecode
687.4 Disturbance of skin sensation Dermatologic 1.18 1.14 – 1.22 1.26e-17 2884 28859 all phecode
689 Disorder of skin and subcutaneous tissue NOS Dermatologic 1.06 1.04 – 1.09 7.43e-06 5747 57521 all phecode
690 Erythematosquamous dermatosis Dermatologic 0.991 0.786 – 1.25 0.94 71 710 all phecode
690.1 Seborrheic dermatitis Dermatologic 1.06 0.82 – 1.37 0.654 53 530 all phecode
691 Congenital anomalies of skin Dermatologic 1.07 0.889 – 1.28 0.494 120 1199 all phecode
694 Dyschromia and Vitiligo Dermatologic 1.05 0.986 – 1.12 0.128 986 9854 all phecode
694.1 Vitiligo Dermatologic 1.24 0.961 – 1.6 0.099 60 599 all phecode
694.2 Other dyschromia Dermatologic 0.982 0.912 – 1.06 0.632 782 7821 all phecode
694.3 Vascular disorders of skin Dermatologic 1.4 1.17 – 1.68 0.000324 117 1170 all phecode
695 Erythematous conditions Dermatologic 1.11 1.06 – 1.16 9.79e-07 2379 23813 all phecode
695.1 Toxic erythema Dermatologic 1.23 1.02 – 1.48 0.0326 109 1090 all phecode
695.2 Bullous dermatoses Dermatologic 1.11 0.941 – 1.32 0.211 137 1365 all phecode
695.21 Dermatitis herpetiformis Dermatologic 1.29 0.998 – 1.66 0.052 57 569 all phecode
695.22 Pemphigus and pemphigoid Dermatologic 0.949 0.756 – 1.19 0.654 73 727 all phecode
695.3 Rosacea Dermatologic 1.06 0.95 – 1.19 0.287 309 3097 all phecode
695.4 Lupus (localized and systemic) Dermatologic 1.03 0.927 – 1.14 0.609 411 4114 all phecode
695.41 Cutaneous lupus erythematosus Dermatologic 0.904 0.756 – 1.08 0.272 130 1295 all phecode
695.42 Systemic lupus erythematosus Dermatologic 1.05 0.942 – 1.18 0.367 340 3407 all phecode
695.7 Prurigo and Lichen Dermatologic 1.14 1.06 – 1.23 0.000459 775 7760 all phecode
695.8 Other specified erythematous conditions Dermatologic 1.16 1.01 – 1.32 0.0312 236 2359 all phecode
695.81 Erythema nodosum Dermatologic 1.06 0.835 – 1.33 0.652 76 760 all phecode
695.9 Unspecified erythematous condition Dermatologic 1.09 0.992 – 1.2 0.0717 467 4672 all phecode
696 Psoriasis and related disorders Dermatologic 1.23 1.18 – 1.29 3.43e-22 2252 22509 all phecode
696.4 Psoriasis Dermatologic 1.25 1.19 – 1.3 2.04e-23 2198 21969 all phecode
696.41 Psoriasis vulgaris Dermatologic 1.26 1.2 – 1.33 1.12e-20 1680 16796 all phecode
696.42 Psoriatic arthropathy Dermatologic 1.18 1.1 – 1.28 1.21e-05 706 7052 all phecode
697 Sarcoidosis Dermatologic 1.18 1.08 – 1.29 0.000144 539 5373 all phecode
698 Pruritus and related conditions Dermatologic 1.2 1.11 – 1.29 1.2e-06 782 7814 all phecode
700 Corns and callosities Dermatologic 1.05 0.933 – 1.18 0.431 291 2904 all phecode
701
Other hypertrophic and atrophic conditions of
Other hypertrophic and atrophic conditions of skin
 Dermatologic 1.1 1.07 – 1.13 1.11e-09 4663 46650 all phecode
701.1 Keratoderma, acquired Dermatologic 1.06 0.854 – 1.31 0.613 87 870 all phecode
701.2 Scar conditions and fibrosis of skin Dermatologic 1.07 1.02 – 1.11 0.00244 2348 23478 all phecode
701.3 Circumscribed scleroderma Dermatologic 1.14 0.872 – 1.49 0.335 61 610 all phecode
701.4 Keloid scar Dermatologic 1.09 0.949 – 1.26 0.216 216 2159 all phecode
701.5 Abnormal granulation tissue Dermatologic 1.08 0.986 – 1.19 0.0954 455 4568 all phecode
701.6 Acquired acanthosis nigricans Dermatologic 1.22 0.999 – 1.49 0.0514 102 1019 all phecode
702
Degenerative skin conditions and other
Degenerative skin conditions and other dermatoses
 Dermatologic 1.01 0.985 – 1.04 0.383 5459 54587 all phecode
702.1 Actinic keratosis Dermatologic 1.01 0.968 – 1.05 0.723 2585 25842 all phecode
702.2 Seborrheic keratosis Dermatologic 1.02 0.984 – 1.06 0.266 3078 30772 all phecode
703 Diseases of nail, NOS Dermatologic 1.11 0.994 – 1.23 0.065 354 3539 all phecode
703.1 Ingrowing nail Dermatologic 1.18 1.1 – 1.26 8.92e-07 966 9660 all phecode
704 Diseases of hair and hair follicles Dermatologic 1.08 1.05 – 1.11 3.21e-08 5267 52727 all phecode
704.1 Alopecia Dermatologic 1.27 1.06 – 1.53 0.00937 125 1269 all phecode
704.8
Other specified diseases of hair and hair
Other specified diseases of hair and hair follicles
 Dermatologic 1.13 0.886 – 1.44 0.326 76 759 all phecode
705 Disorders of sweat glands Dermatologic 1.27 1.11 – 1.46 0.000386 228 2287 all phecode
705.3 Hidradenitis Dermatologic 1.36 1.18 – 1.58 4.06e-05 186 1868 all phecode
705.8 Hyperhidrosis Dermatologic 1.14 1.05 – 1.24 0.00121 591 5919 all phecode
706 Diseases of sebaceous glands Dermatologic 1.07 1.04 – 1.09 1.38e-08 8317 83195 all phecode
706.1 Acne Dermatologic 1.1 0.881 – 1.38 0.395 78 779 all phecode
706.2 Sebaceous cyst Dermatologic 1.06 1.04 – 1.09 4.69e-08 8787 87882 all phecode
707 Chronic ulcer of skin Dermatologic 1.61 1.54 – 1.68 3.94e-102 1953 19654 all phecode
707.1 Decubitus ulcer Dermatologic 1.35 1.27 – 1.44 4.21e-20 909 9097 all phecode
709 Diffuse diseases of connective tissue Dermatologic 1.18 1.14 – 1.23 6.06e-22 3432 34317 all phecode
709.2 Sicca syndrome Dermatologic 1.1 1 – 1.2 0.0495 508 5073 all phecode
709.3 Systemic sclerosis Dermatologic 1 0.855 – 1.17 0.992 176 1753 all phecode
709.6
Other specified diffuse diseases of connective
Other specified diffuse diseases of connective tissue
 Dermatologic 1.02 0.798 – 1.31 0.853 65 649 all phecode
709.7 Unspecified diffuse connective tissue disease Dermatologic 1.21 1.17 – 1.26 3.09e-23 2714 27144 all phecode
710
Osteomyelitis, periostitis, and other
Osteomyelitis, periostitis, and other infections involving bone
 Musculoskeletal 1.66 1.53 – 1.8 1.89e-35 602 6034 all phecode
710.1 Osteomyelitis Musculoskeletal 1.72 1.58 – 1.87 2.29e-37 556 5574 all phecode
710.12 Chronic osteomyelitis Musculoskeletal 1.51 1.31 – 1.74 1.03e-08 194 1947 all phecode
710.19 Unspecified osteomyelitis Musculoskeletal 1.83 1.67 – 2.02 1.56e-34 398 3997 all phecode
711 Arthropathy associated with infections Musculoskeletal 1.27 1.16 – 1.4 1.05e-06 421 4225 all phecode
711.1 Pyogenic arthritis Musculoskeletal 1.32 1.18 – 1.47 8.91e-07 328 3296 all phecode
712 Infective connective tissue disorders Musculoskeletal 1.18 0.941 – 1.48 0.151 81 810 all phecode
713
Arthropathy associated with other disorders
Arthropathy associated with other disorders classified elsewhere
 Musculoskeletal 1.72 1.47 – 2.01 1.37e-11 148 1499 all phecode
713.5
Arthropathy associated with neurological
Arthropathy associated with neurological disorders
 Musculoskeletal 3.74 2.77 – 5.05 9.02e-18 65 669 all phecode
714
Rheumatoid arthritis and other inflammatory
Rheumatoid arthritis and other inflammatory polyarthropathies
 Musculoskeletal 1.23 1.2 – 1.27 1.15e-44 4832 48320 all phecode
714.1 Rheumatoid arthritis Musculoskeletal 1.22 1.19 – 1.26 2.39e-38 4372 43714 all phecode
715 Other inflammatory spondylopathies Musculoskeletal 1.22 1.16 – 1.28 1.79e-14 1659 16588 all phecode
715.1 Sacroiliitis NEC Musculoskeletal 1.16 0.95 – 1.41 0.147 113 1129 all phecode
715.2 Ankylosing spondylitis Musculoskeletal 1.11 1.03 – 1.21 0.0107 618 6177 all phecode
716 Other arthropathies Musculoskeletal 1.21 1.2 – 1.22 1.05e-263 37478 265375 all phecode
716.1 Unspecified polyarthropathy or polyarthritis Musculoskeletal 1.27 1.23 – 1.32 5.41e-44 3505 35090 all phecode
716.2 Unspecified monoarthritis Musculoskeletal 1.2 1.18 – 1.22 5.32e-111 15522 155339 all phecode
716.9 Arthropathy NOS Musculoskeletal 1.21 1.2 – 1.22 2.31e-256 35944 262308 all phecode
717 Polymyalgia Rheumatica Musculoskeletal 1.2 1.13 – 1.27 1.54e-09 1145 11480 all phecode
720 Spinal stenosis Musculoskeletal 1.22 1.18 – 1.26 1.19e-33 3705 37091 all phecode
721 Spondylosis and allied disorders Musculoskeletal 1.22 1.19 – 1.25 6.74e-66 7832 78318 all phecode
721.1 Spondylosis without myelopathy Musculoskeletal 1.23 1.19 – 1.26 5.99e-46 5045 50451 all phecode
721.2 Spondylosis with myelopathy Musculoskeletal 1.4 1.21 – 1.62 7.68e-06 189 1899 all phecode
721.8 Other allied disorders of spine Musculoskeletal 1.2 1.08 – 1.34 0.000744 352 3519 all phecode
722 Intervertebral disc disorders Musculoskeletal 1.19 1.16 – 1.21 6.69e-54 8978 89848 all phecode
722.1 Displacement of intervertebral disc Musculoskeletal 1.11 1.02 – 1.22 0.0191 512 5116 all phecode
722.6 Degeneration of intervertebral disc Musculoskeletal 1.21 1.17 – 1.26 6.39e-23 2831 28328 all phecode
722.8 Postlaminectomy syndrome Musculoskeletal 1.31 1.02 – 1.69 0.0337 67 669 all phecode
722.9 Other and unspecified disc disorder Musculoskeletal 1.16 1.13 – 1.2 4.62e-22 4407 44127 all phecode
723 Other disorders of cervical region Musculoskeletal 1.21 1.1 – 1.32 3.67e-05 517 5173 all phecode
723.1 Torticollis Musculoskeletal 1.22 1.01 – 1.48 0.043 107 1068 all phecode
724 Other and unspecified disorders of back Musculoskeletal 1.15 1.1 – 1.2 2e-09 2052 20514 all phecode
724.1 Disorders of sacrum Musculoskeletal 1.25 1.13 – 1.39 1.46e-05 403 4024 all phecode
724.2 Disorders of coccyx Musculoskeletal 1.24 1.12 – 1.37 4.72e-05 406 4054 all phecode
724.8 Other symptoms referable to back Musculoskeletal 1.53 1.2 – 1.95 0.000658 63 630 all phecode
724.9 Other unspecified back disorders Musculoskeletal 1.11 1.05 – 1.17 8.52e-05 1614 16139 all phecode
726 Peripheral enthesopathies and allied syndromes Musculoskeletal 1.17 1.15 – 1.19 7.71e-76 14663 146691 all phecode
726.1 Enthesopathy Musculoskeletal 1.17 1.14 – 1.19 8e-48 9589 95900 all phecode
726.2 Synoviopathy Musculoskeletal 1.29 1.15 – 1.45 9.2e-06 334 3336 all phecode
726.3 Bursitis Musculoskeletal 1.17 1.09 – 1.26 6.39e-06 854 8573 all phecode
727 Other disorders of synovium, tendon, and bursa Musculoskeletal 1.12 1.09 – 1.15 6.96e-20 7331 73332 all phecode
727.1 Synovitis and tenosynovitis Musculoskeletal 1.15 1.1 – 1.19 9.01e-12 2737 27406 all phecode
727.2 Bursitis disorders Musculoskeletal 1.22 0.994 – 1.49 0.0569 103 1029 all phecode
727.4 Ganglion and cyst of synovium, tendon, and bursa Musculoskeletal 1.09 1.05 – 1.13 3.21e-06 3109 31085 all phecode
727.5 Rupture of synovium Musculoskeletal 1.07 0.985 – 1.16 0.107 586 5854 all phecode
727.6 Rupture of tendon, nontraumatic Musculoskeletal 1.13 1.02 – 1.26 0.0246 353 3527 all phecode
727.7 Contracture of tendon (sheath) Musculoskeletal 1.09 0.917 – 1.29 0.332 143 1429 all phecode
728 Disorders of muscle, ligament, and fascia Musculoskeletal 1.06 1.03 – 1.1 0.000386 3677 36788 all phecode
728.2 Laxity of ligament or hypermobility syndrome Musculoskeletal 1.11 1 – 1.23 0.042 412 4115 all phecode
728.7 Fasciitis Musculoskeletal 1.06 1.03 – 1.1 0.000165 3803 38045 all phecode
728.71
Contracture of palmar fascia [Dupuytren's
Contracture of palmar fascia [Dupuytren's disease]
 Musculoskeletal 1.06 1.02 – 1.1 0.000942 3477 34788 all phecode
729 Other disorders of soft tissues Musculoskeletal 1.26 1.22 – 1.29 1.91e-66 6014 60309 all phecode
729.1 Rheumatism, unspecified and fibrositis Musculoskeletal 1.3 1.22 – 1.39 6.03e-16 1005 10063 all phecode
729.3 Panniculitis Musculoskeletal 1.14 0.931 – 1.4 0.203 101 1009 all phecode
731
Osteitis deformans and osteopathies associated
Osteitis deformans and osteopathies associated with other disorders classified elsewhere
 Musculoskeletal 1.23 1.09 – 1.39 0.00101 276 2758 all phecode
731.1 Osteitis deformans [Paget's disease of bone] Musculoskeletal 1.22 1.07 – 1.38 0.00236 261 2609 all phecode
732 Osteochondropathies Musculoskeletal 1.06 0.956 – 1.16 0.284 467 4679 all phecode
732.1 Juvenile osteochondrosis Musculoskeletal 1.01 0.873 – 1.17 0.895 207 2068 all phecode
732.7 Osteochondritis dissecans Musculoskeletal 0.88 0.664 – 1.17 0.373 57 570 all phecode
733 Other disorders of bone and cartilage Musculoskeletal 1.08 1.03 – 1.13 0.00231 1777 17814 all phecode
733.2 Cyst of bone Musculoskeletal 1.18 1.05 – 1.33 0.00575 311 3115 all phecode
733.4 Aseptic necrosis of bone Musculoskeletal 1.05 0.966 – 1.15 0.234 540 5393 all phecode
733.6 Costochondritis Musculoskeletal 1.33 1.11 – 1.59 0.00179 128 1276 all phecode
733.8 Malunion and nonunion of fracture Musculoskeletal 1.09 1.03 – 1.15 0.00494 1231 12313 all phecode
733.9 Chondromalacia Musculoskeletal 1.28 1.06 – 1.54 0.00914 121 1206 all phecode
735 Acquired foot deformities Musculoskeletal 1.03 1.01 – 1.06 0.00207 9603 96090 all phecode
735.1 Flat foot Musculoskeletal 1.02 0.879 – 1.19 0.768 189 1910 all phecode
735.2 Acquired toe deformities Musculoskeletal 1.06 1.03 – 1.09 0.000123 5070 50712 all phecode
735.21 Hammer toe (acquired) Musculoskeletal 1.06 1.01 – 1.11 0.0168 1929 19324 all phecode
735.23 Hallux rigidus Musculoskeletal 1.06 1.01 – 1.12 0.02 1555 15527 all phecode
735.3 Hallux valgus (Bunion) Musculoskeletal 1 0.978 – 1.03 0.785 6643 66463 all phecode
736 Other acquired deformities of limbs Musculoskeletal 1.08 1.03 – 1.13 0.00295 1627 16282 all phecode
736.2 Acquired deformities of finger Musculoskeletal 0.958 0.843 – 1.09 0.506 248 2476 all phecode
737 Curvature of spine Musculoskeletal 1.06 0.995 – 1.12 0.0726 1128 11300 all phecode
737.3 Kyphoscoliosis and scoliosis Musculoskeletal 1.04 0.98 – 1.11 0.183 1061 10632 all phecode
738 Other acquired musculoskeletal deformity Musculoskeletal 1.15 1.1 – 1.21 3.54e-09 1904 19058 all phecode
738.4 Acquired spondylolisthesis Musculoskeletal 1.17 1.11 – 1.23 4.75e-09 1513 15147 all phecode
739 Contracture of joint Musculoskeletal 1.07 0.977 – 1.18 0.139 488 4884 all phecode
740 Osteoarthrosis Musculoskeletal 1.15 1.13 – 1.16 1.26e-107 27707 231603 all phecode
740.1 Osteoarthritis; localized Musculoskeletal 1.11 1.1 – 1.13 4.6e-43 17412 169419 all phecode
740.11 Osteoarthrosis, localized, primary Musculoskeletal 1.14 1.11 – 1.16 2.19e-31 8974 89750 all phecode
740.12 Osteoarthrosis, localized, secondary Musculoskeletal 0.967 0.868 – 1.08 0.551 348 3474 all phecode
740.2 Osteoarthrosis, generalized Musculoskeletal 1.19 1.1 – 1.29 2.38e-05 598 5969 all phecode
740.9 Osteoarthrosis NOS Musculoskeletal 1.22 1.19 – 1.24 2.84e-98 12270 122792 all phecode
741 Symptoms and disorders of the joints Musculoskeletal 1.15 1.11 – 1.19 1.07e-15 3563 35648 all phecode
741.1 Ankylosis of joint Musculoskeletal 1.19 0.985 – 1.44 0.0712 102 1019 all phecode
741.2 Stiffness of joint Musculoskeletal 1.1 1.01 – 1.2 0.0223 614 6146 all phecode
741.3 Difficulty in walking Musculoskeletal 1.32 1.12 – 1.54 0.000794 154 1540 all phecode
741.4 Joint effusions Musculoskeletal 1.17 1.11 – 1.24 4.69e-09 1418 14197 all phecode
741.5 Hemarthrosis Musculoskeletal 1.14 0.942 – 1.37 0.181 110 1100 all phecode
741.6 Villonodular synovitis Musculoskeletal 1.08 0.813 – 1.42 0.609 54 535 all phecode
742 Derangement of joint, non-traumatic Musculoskeletal 1.13 1.08 – 1.17 1.55e-09 2843 28441 all phecode
742.1 Loose body in joint Musculoskeletal 1.09 0.973 – 1.21 0.143 333 3337 all phecode
742.2
Pathological, developmental or recurrent
Pathological, developmental or recurrent dislocation
 Musculoskeletal 1.32 1.07 – 1.62 0.00942 95 960 all phecode
742.8 Articular cartilage disorder Musculoskeletal 1.16 1.06 – 1.26 0.00118 500 4996 all phecode
742.9 Other derangement of joint Musculoskeletal 1.12 1.07 – 1.17 2.82e-06 1993 19926 all phecode
743
Osteoporosis, osteopenia and pathological
Osteoporosis, osteopenia and pathological fracture
 Musculoskeletal 1.07 1.04 – 1.09 2.89e-08 7563 75729 all phecode
743.1 Osteoporosis Musculoskeletal 1.07 1.04 – 1.09 1.13e-06 6400 64107 all phecode
743.11 Osteoporosis NOS Musculoskeletal 1.07 1.04 – 1.09 7.78e-06 5549 55604 all phecode
743.13 Other specified osteoporosis Musculoskeletal 1.17 1.07 – 1.27 0.000681 529 5283 all phecode
743.2 Pathologic fracture Musculoskeletal 1.14 1.05 – 1.25 0.00263 516 5179 all phecode
743.9
Osteopenia or other disorder of bone and
Osteopenia or other disorder of bone and cartilage
 Musculoskeletal 1.03 0.963 – 1.11 0.351 815 8144 all phecode
745 Pain in joint Musculoskeletal 1.18 1.16 – 1.21 1.85e-48 7975 79789 all phecode
747 Cardiac and circulatory congenital anomalies Congenital Anomalies 1.22 1.18 – 1.27 7.78e-26 2802 28058 all phecode
747.1 Cardiac congenital anomalies Congenital Anomalies 1.23 1.18 – 1.28 6.2e-26 2628 26323 all phecode
747.11 Cardiac shunt/ heart septal defect Congenital Anomalies 0.958 0.878 – 1.04 0.33 584 5838 all phecode
747.12 Valvular heart disease/ heart chambers Congenital Anomalies 1.04 0.91 – 1.19 0.564 235 2358 all phecode
747.13 Congenital anomalies of great vessels Congenital Anomalies 1.33 1.27 – 1.39 2.52e-34 1816 18200 all phecode
747.2
Congenital anomalies of peripheral vascular
Congenital anomalies of peripheral vascular system
 Congenital Anomalies 1.14 0.968 – 1.33 0.119 167 1680 all phecode
748 Anomalies of respiratory system, congenital Congenital Anomalies 1.08 0.806 – 1.44 0.619 51 510 all phecode
749 Congenital anomalies of face and neck Congenital Anomalies 1.01 0.9 – 1.14 0.839 303 3029 all phecode
750 Digestive congenital anomalies Congenital Anomalies 0.969 0.896 – 1.05 0.435 686 6870 all phecode
750.1 Upper gastrointestinal congenital anomalies Congenital Anomalies 0.952 0.851 – 1.07 0.395 327 3263 all phecode
750.13 Congenital anomalies of mouth/tongue Congenital Anomalies 0.862 0.743 – 1 0.052 191 1909 all phecode
750.2 Lower gastrointestinal congenital anomalies Congenital Anomalies 0.996 0.894 – 1.11 0.945 356 3574 all phecode
750.21 Congenital anomalies of intestine Congenital Anomalies 0.916 0.8 – 1.05 0.205 225 2256 all phecode
750.22
Congenital anomaly of gallbladder, bile ducts
Congenital anomaly of gallbladder, bile ducts, liver, pancreas
 Congenital Anomalies 1.12 0.925 – 1.37 0.239 117 1179 all phecode
751 Genitourinary congenital anomalies Congenital Anomalies 1.02 0.969 – 1.07 0.44 1527 15286 all phecode
751.1 Congenital anomalies of genital organs Congenital Anomalies 0.988 0.913 – 1.07 0.756 694 6932 all phecode
751.11 Congenital anomalies of female genital organs Congenital Anomalies 0.991 0.897 – 1.1 0.863 455 4546 all phecode
751.12 Congenital anomalies of male genital organs Congenital Anomalies 0.97 0.849 – 1.11 0.65 222 2217 all phecode
751.2 Congenital anomalies of urinary system Congenital Anomalies 1.07 0.999 – 1.15 0.0538 836 8385 all phecode
751.21 Cystic kidney disease Congenital Anomalies 1.05 0.951 – 1.15 0.347 424 4246 all phecode
751.22 Other specified congenital anomalies of kidney Congenital Anomalies 1.1 0.987 – 1.22 0.0868 333 3346 all phecode
752 Nervous system congenital anomalies Congenital Anomalies 1.13 1.01 – 1.26 0.0333 328 3307 all phecode
752.1 Neural tube defects Congenital Anomalies 1.08 0.949 – 1.23 0.244 253 2557 all phecode
752.11 Spina bifida Congenital Anomalies 1.02 0.886 – 1.18 0.773 208 2108 all phecode
752.2
Other specified congenital anomalies of nervous
Other specified congenital anomalies of nervous system
 Congenital Anomalies 1.29 1.02 – 1.63 0.031 78 780 all phecode
753 Congenital anomalies of the eye Congenital Anomalies 1.34 1.12 – 1.6 0.0015 127 1270 all phecode
753.1 Congenital cataract and lens anomalies Congenital Anomalies 1.37 1.08 – 1.73 0.00864 76 760 all phecode
754 Congenital musculoskeletal deformities of spine Congenital Anomalies 1.16 0.957 – 1.4 0.13 109 1099 all phecode
755 Congenital anomalies of limbs Congenital Anomalies 1.15 1.04 – 1.27 0.00499 425 4276 all phecode
755.1 Congenital deformities of feet Congenital Anomalies 1.13 0.982 – 1.29 0.0891 208 2086 all phecode
755.6
Other congenital anomalies of lower limb
Other congenital anomalies of lower limb, including pelvic girdle
 Congenital Anomalies 1.11 0.941 – 1.31 0.218 160 1620 all phecode
755.61 Congenital hip dysplasia and deformity Congenital Anomalies 1.1 0.902 – 1.35 0.336 106 1070 all phecode
756 Other congenital musculoskeletal anomalies Congenital Anomalies 1.08 0.992 – 1.17 0.0783 587 5872 all phecode
756.3
Congenital anomalies of muscle, tendon, fascia
Congenital anomalies of muscle, tendon, fascia, and connective tissue
 Congenital Anomalies 1.16 0.922 – 1.45 0.208 81 810 all phecode
756.5 Congenital osteodystrophies Congenital Anomalies 1.08 0.983 – 1.19 0.107 435 4356 all phecode
758 Chromosomal anomalies and genetic disorders Congenital Anomalies 0.928 0.781 – 1.1 0.395 148 1708 all phecode
758.1 Chromosomal anomalies Congenital Anomalies 1.02 0.786 – 1.31 0.904 60 830 all phecode
759 Other and unspecified congenital anomalies Congenital Anomalies 1.09 0.954 – 1.25 0.196 216 2159 all phecode
759.1 Anomalies of endocrine glands, congenital Congenital Anomalies 1.12 0.918 – 1.38 0.258 96 959 all phecode
760 Back pain Symptoms 1.19 1.16 – 1.21 5.62e-68 11126 111353 all phecode
761 Cervicalgia Symptoms 1.17 1.12 – 1.23 1.07e-10 1791 17901 all phecode
764 Sciatica Symptoms 1.19 1.14 – 1.24 5.07e-16 2372 23732 all phecode
766 Neuralgia, neuritis, and radiculitis NOS Symptoms 1.15 1.08 – 1.22 4.55e-06 1172 11738 all phecode
770 Myalgia and myositis unspecified Symptoms 1.21 1.11 – 1.31 6.72e-06 631 6311 all phecode
771 Musculoskeletal symptoms referable to limbs Symptoms 1.23 1.15 – 1.32 3.26e-09 870 8687 all phecode
771.1 Swelling of limb Symptoms 1.24 1.21 – 1.28 1.06e-47 4617 46330 all phecode
772 Symptoms of the muscles Symptoms 1.17 1.09 – 1.27 5.84e-05 659 6581 all phecode
773 Pain in limb Symptoms 1.19 1.16 – 1.22 2.49e-39 6209 62203 all phecode
780 Hypothermia/Chills Symptoms 1.24 1.06 – 1.44 0.00577 171 1719 all phecode
781
Symptoms involving nervous and musculoskeletal
Symptoms involving nervous and musculoskeletal systems
 Symptoms 1.22 1.17 – 1.28 2.17e-17 1870 18715 all phecode
782.3 Edema Symptoms 1.32 1.26 – 1.39 1.17e-29 1642 16450 all phecode
782.6 Pallor and flushing Symptoms 1.26 1.09 – 1.47 0.00202 175 1748 all phecode
783 Fever of unknown origin Symptoms 1.15 1.11 – 1.18 1.19e-16 3911 39105 all phecode
785 Abdominal pain Symptoms 1.11 1.1 – 1.13 6.3e-92 40080 301686 all phecode
788 Syncope and collapse Symptoms 1.15 1.12 – 1.17 3.91e-38 9069 90813 all phecode
789 Nausea and vomiting Symptoms 1.21 1.18 – 1.23 4.12e-85 11577 115807 all phecode
790 Nonspecific findings on examination of blood Symptoms 1.11 0.94 – 1.31 0.223 150 1500 all phecode
790.1 Elevated sedimentation rate Symptoms 1.26 1.02 – 1.55 0.0321 84 840 all phecode
790.6 Other abnormal blood chemistry Symptoms 1.12 1.09 – 1.15 1.47e-19 6357 63635 all phecode
791 Gangrene Symptoms 1.72 1.59 – 1.87 5.4e-39 549 5501 all phecode
792
Abnormal Papanicolaou smear of cervix and
Abnormal Papanicolaou smear of cervix and cervical HPV
 Symptoms 0.901 0.725 – 1.12 0.351 98 966 all phecode
793
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of musculoskeletal system
 Symptoms 0.985 0.831 – 1.17 0.859 134 1340 all phecode
793.2
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of other intrathoracic organs (echocardiogram, etc)
 Symptoms 1.15 1.06 – 1.25 0.00119 565 5647 all phecode
794
Abnormal results of other function studies
Abnormal results of other function studies (bladder, pancreas, placenta, spleen, etc)
 Symptoms 1.04 0.86 – 1.25 0.694 120 1198 all phecode
797 Shock Symptoms 1.24 1.05 – 1.46 0.0124 156 1559 all phecode
797.1 Cardiogenic shock Symptoms 1.37 1.12 – 1.68 0.00211 102 1020 all phecode
798 Malaise and fatigue Symptoms 1.2 1.16 – 1.24 5.5e-25 3408 34103 all phecode
798.1 Chronic fatigue syndrome Symptoms 1.14 1.04 – 1.24 0.00308 591 5913 all phecode
800 Fracture of lower limb Injuries & Poisonings 1.08 1.05 – 1.1 4.15e-09 7035 70329 all phecode
800.1 Fracture of neck of femur Injuries & Poisonings 1.04 0.989 – 1.09 0.131 1815 18152 all phecode
800.2 Fracture of unspecified part of femur Injuries & Poisonings 1.08 0.927 – 1.27 0.314 170 1693 all phecode
800.3 Fracture of tibia and fibula Injuries & Poisonings 1.07 1.02 – 1.11 0.00378 2158 21577 all phecode
800.4 Fracture of patella Injuries & Poisonings 1.04 0.97 – 1.12 0.254 766 7661 all phecode
801 Fracture of ankle and foot Injuries & Poisonings 1.11 1.06 – 1.16 4.54e-06 2205 22041 all phecode
801.1 Fracture of foot Injuries & Poisonings 1.07 1.02 – 1.12 0.00523 1835 18346 all phecode
802 Fracture of pelvis Injuries & Poisonings 0.984 0.911 – 1.06 0.675 718 7185 all phecode
803 Fracture of upper limb Injuries & Poisonings 0.995 0.973 – 1.02 0.671 8288 82880 all phecode
803.1 Fracture of humerus Injuries & Poisonings 1.1 1.05 – 1.15 0.000188 1691 16883 all phecode
803.2 Fracture of radius and ulna Injuries & Poisonings 0.955 0.927 – 0.983 0.00162 5215 52171 all phecode
803.3 Fracture of clavicle or scapula Injuries & Poisonings 1.04 0.985 – 1.09 0.159 1518 15186 all phecode
804 Fracture of hand or wrist Injuries & Poisonings 0.999 0.963 – 1.03 0.935 3339 33384 all phecode
805
Fracture of vertebral column without mention of
Fracture of vertebral column without mention of spinal cord injury
 Injuries & Poisonings 1.07 1.02 – 1.14 0.0119 1358 13565 all phecode
807 Fracture of ribs Injuries & Poisonings 1.02 0.95 – 1.1 0.572 776 7752 all phecode
809 Fracture of unspecified bones Injuries & Poisonings 1.03 0.973 – 1.09 0.312 1300 12998 all phecode
817 Concussion Injuries & Poisonings 0.887 0.777 – 1.01 0.0768 243 2428 all phecode
818 Intracranial hemorrhage (injury) Injuries & Poisonings 1.15 1.05 – 1.25 0.00155 522 5213 all phecode
819
Skull and face fracture and other intercranial
Skull and face fracture and other intercranial injury
 Injuries & Poisonings 1.04 1 – 1.08 0.0269 2957 29596 all phecode
823 Torus fracture Injuries & Poisonings 1.04 0.988 – 1.09 0.141 1673 16710 all phecode
830 Dislocation Injuries & Poisonings 1.04 0.997 – 1.09 0.0691 2088 20872 all phecode
835 Internal derangement of knee Injuries & Poisonings 1.1 1.08 – 1.12 7.69e-29 15221 152247 all phecode
836 Traumatic arthropathy Injuries & Poisonings 1.2 1.1 – 1.3 5.61e-05 526 5267 all phecode
840 Sprains and strains Injuries & Poisonings 0.955 0.868 – 1.05 0.341 470 4697 all phecode
850 Hemorrhage or hematoma complicating a procedure Injuries & Poisonings 1.15 1.12 – 1.19 2.23e-23 5259 52626 all phecode
851
Complications of transplants and reattached
Complications of transplants and reattached limbs
 Injuries & Poisonings 1.29 1.09 – 1.52 0.00273 157 1567 all phecode
853 Complication of colostomy or enterostomy Injuries & Poisonings 1.28 1.18 – 1.4 2.07e-08 501 5010 all phecode
854
Complications of cardiac/vascular device
Complications of cardiac/vascular device, implant, and graft
 Injuries & Poisonings 1.34 1.28 – 1.4 1.79e-36 1826 18238 all phecode
857
Mechanical complication of unspecified
Mechanical complication of unspecified genitourinary device, implant, and graft
 Injuries & Poisonings 1.16 1.1 – 1.23 1.86e-07 1241 12418 all phecode
858 Complication of internal orthopedic device Injuries & Poisonings 1.15 1.11 – 1.2 5.56e-15 3158 31607 all phecode
859
Complication due to other implant and internal
Complication due to other implant and internal device
 Injuries & Poisonings 1.16 1.12 – 1.2 2.08e-16 3259 32599 all phecode
860 Bone marrow or stem cell transplant Neoplasms 1.15 0.893 – 1.48 0.281 68 680 all phecode
870 Open wounds of head; neck; and trunk Injuries & Poisonings 1.07 1.04 – 1.11 4.52e-05 3502 35062 all phecode
870.1 Open wound or laceration of eye or eyelid Injuries & Poisonings 1.11 0.987 – 1.25 0.082 272 2713 all phecode
870.2 Open wound of ear Injuries & Poisonings 0.935 0.806 – 1.08 0.373 196 1949 all phecode
870.3 Other open wound of head and face Injuries & Poisonings 1.07 1.03 – 1.11 0.000864 2904 29085 all phecode
870.4 Open wound of nose and sinus Injuries & Poisonings 1.02 0.89 – 1.16 0.795 220 2199 all phecode
870.6 Open wound of neck Injuries & Poisonings 1 0.783 – 1.28 0.991 68 678 all phecode
871 Open wounds of extremities Injuries & Poisonings 1.04 1.01 – 1.08 0.00853 4063 40648 all phecode
871.1 Open wound of hand except finger(s) Injuries & Poisonings 1.39 1.07 – 1.8 0.0133 53 530 all phecode
871.2 Open wound of finger(s) Injuries & Poisonings 0.994 0.81 – 1.22 0.957 91 900 all phecode
871.3 Open wound of foot except toe(s) alone Injuries & Poisonings 1.14 0.981 – 1.33 0.0868 178 1785 all phecode
872 Traumatic amputation Injuries & Poisonings 0.991 0.903 – 1.09 0.84 475 4742 all phecode
873 Broken tooth Injuries & Poisonings 1.09 0.957 – 1.25 0.187 229 2289 all phecode
874 Complication of amputation stump Injuries & Poisonings 1.5 1.29 – 1.74 1.49e-07 169 1710 all phecode
905
Late effects of musculoskeletal and connective
Late effects of musculoskeletal and connective tissue injuries
 Injuries & Poisonings 1.16 0.983 – 1.36 0.0791 157 1567 all phecode
907 Injuries to the nervous system Injuries & Poisonings 1.15 1.08 – 1.21 2.01e-06 1314 13140 all phecode
915 Superficial injury without mention of infection Injuries & Poisonings 1.17 1.13 – 1.21 2.68e-23 4260 42663 all phecode
916 Contusion Injuries & Poisonings 1.14 1.08 – 1.2 2.36e-06 1450 14506 all phecode
930 Allergic reaction to food Injuries & Poisonings 1.27 1.09 – 1.47 0.00235 179 1807 all phecode
938 Dermatitis due to solar radiation Injuries & Poisonings 1.08 0.977 – 1.2 0.128 389 3899 all phecode
938.2 Chronic dermatitis due to solar radiation Injuries & Poisonings 1.1 0.966 – 1.24 0.156 252 2530 all phecode
939
Atopic/contact dermatitis due to other or
Atopic/contact dermatitis due to other or unspecified
 Dermatologic 1.09 1.05 – 1.14 6.42e-05 2094 20961 all phecode
941 Adverse reaction to serum or vaccine Injuries & Poisonings 1.14 0.992 – 1.3 0.0658 225 2249 all phecode
942 Infusion and transfusion reaction Injuries & Poisonings 1.22 0.993 – 1.5 0.0588 104 1038 all phecode
946 Anaphylactic shock NOS Injuries & Poisonings 1.31 1.2 – 1.43 6.24e-10 550 5509 all phecode
947 Urticaria Injuries & Poisonings 1.24 1.12 – 1.38 5.45e-05 371 3707 all phecode
949 Allergies, other Injuries & Poisonings 1.14 1.03 – 1.26 0.0126 397 3989 all phecode
952
Spinal cord injury without evidence of spinal
Spinal cord injury without evidence of spinal bone injury
 Injuries & Poisonings 1.07 0.969 – 1.18 0.177 423 4224 all phecode
957 Injury to other and unspecified nerves Injuries & Poisonings 1.38 1.22 – 1.56 1.4e-07 269 2698 all phecode
958
Certain early complications of trauma or
Certain early complications of trauma or procedure
 Injuries & Poisonings 1.14 1.04 – 1.24 0.00612 491 4926 all phecode
958.1 Postoperative shock Injuries & Poisonings 1.32 1.02 – 1.71 0.0324 55 555 all phecode
958.2 Traumatic and surgical subcutaneous emphysema Injuries & Poisonings 0.965 0.764 – 1.22 0.761 74 740 all phecode
960 Poisoning by antibiotics Injuries & Poisonings 1.17 1.16 – 1.19 5.04e-95 18100 181147 all phecode
960.2 Allergy/adverse effect of penicillin Injuries & Poisonings 1.17 1.15 – 1.19 2.1e-83 15846 158623 all phecode
961 Poisoning by other anti-infectives Injuries & Poisonings 1.22 1.1 – 1.34 0.000146 420 4195 all phecode
961.1 Poisoning/allergy of sulfonamides Injuries & Poisonings 1.15 1.07 – 1.24 7.19e-05 869 8703 all phecode
962 Poisoning by hormones and synthetic substitutes Injuries & Poisonings 1.49 1.34 – 1.65 9.66e-14 371 3707 all phecode
962.3
Hormones and synthetic substitutes causing
Hormones and synthetic substitutes causing adverse effects in therapeutic use
 Injuries & Poisonings 1.49 1.34 – 1.65 7.92e-14 364 3638 all phecode
963 Poisoning by primarily systemic agents Injuries & Poisonings 1.2 1.05 – 1.37 0.00935 223 2228 all phecode
964
Poisoning by agents primarily affecting blood
Poisoning by agents primarily affecting blood constituents
 Injuries & Poisonings 1.28 1.14 – 1.43 3.26e-05 282 2830 all phecode
964.1 Anticoagulants causing adverse effects Injuries & Poisonings 1.25 1.12 – 1.41 0.000155 276 2770 all phecode
965
Poisoning by analgesics, antipyretics, and
Poisoning by analgesics, antipyretics, and antirheumatics
 Injuries & Poisonings 1.2 1.17 – 1.23 3.55e-43 6082 60875 all phecode
965.1
Opiates and related narcotics causing adverse
Opiates and related narcotics causing adverse effects in therapeutic use
 Injuries & Poisonings 1.25 1.17 – 1.32 1.46e-12 1144 11447 all phecode
965.2
Antirheumatics causing adverse effects in
Antirheumatics causing adverse effects in therapeutic use
 Injuries & Poisonings 1.26 1.15 – 1.39 1.37e-06 476 4767 all phecode
965.3
Salicylates causing adverse effects in
Salicylates causing adverse effects in therapeutic use
 Injuries & Poisonings 1.3 1.17 – 1.43 5.33e-07 403 4045 all phecode
966
Poisoning by anticonvulsants and
Poisoning by anticonvulsants and anti-Parkinsonism drugs
 Injuries & Poisonings 1.25 1.14 – 1.36 1.92e-06 512 5123 all phecode
967
Adverse effects of sedatives or other central
Adverse effects of sedatives or other central nervous system depressants and anesthetics
 Injuries & Poisonings 1.16 1.06 – 1.26 0.000671 583 5843 all phecode
969 Poisoning by psychotropic agents Injuries & Poisonings 1.24 1.19 – 1.3 3.44e-20 1950 19519 all phecode
971
Poisoning by drugs primarily affecting the
Poisoning by drugs primarily affecting the autonomic nervous system
 Injuries & Poisonings 1.28 1.11 – 1.48 0.000599 190 1908 all phecode
972
Poisoning by agents primarily affecting the
Poisoning by agents primarily affecting the cardiovascular system
 Injuries & Poisonings 1.5 1.34 – 1.69 1.71e-11 271 2717 all phecode
972.6 Antihypertensive agents causing adverse effects Injuries & Poisonings 1.3 1.06 – 1.59 0.0104 84 849 all phecode
973
Poisoning by agents primarily affecting the
Poisoning by agents primarily affecting the gastrointestinal system
 Injuries & Poisonings 1.41 1.17 – 1.71 0.000378 108 1080 all phecode
974
Poisoning by water, mineral, and uric acid
Poisoning by water, mineral, and uric acid metabolism drugs
 Injuries & Poisonings 1.57 1.3 – 1.9 2.34e-06 101 1018 all phecode
975
Poisoning by agents primarily acting on the
Poisoning by agents primarily acting on the smooth and skeletal muscles and respiratory system
 Injuries & Poisonings 1.32 1.04 – 1.69 0.0247 64 640 all phecode
976
Poisoning by agents primarily affecting skin &
Poisoning by agents primarily affecting skin & mucous membrane, ophthalmological, otorhinolaryngological, & dental drugs
 Injuries & Poisonings 1.59 1.22 – 2.06 0.000623 58 580 all phecode
977 Personal history of allergy to medicinal agents Injuries & Poisonings 1.26 1.1 – 1.44 0.000831 234 2337 all phecode
979 Adverse drug events and drug allergies Injuries & Poisonings 1.26 1.16 – 1.36 7.91e-09 698 6966 all phecode
981
Toxic effect of (non-ethyl) alcohol and
Toxic effect of (non-ethyl) alcohol and petroleum and other solvents
 Injuries & Poisonings 1.14 0.987 – 1.32 0.0751 200 1999 all phecode
986 Toxic effect of carbon monoxide Injuries & Poisonings 1.16 0.895 – 1.5 0.265 62 620 all phecode
987 Toxic effect of other gases, fumes, or vapors Injuries & Poisonings 1.34 1.1 – 1.64 0.00394 105 1049 all phecode
988 Toxic effect of noxious substances eaten as food Injuries & Poisonings 1.13 0.929 – 1.37 0.225 111 1128 all phecode
989
Toxic effect of other substances, chiefly
Toxic effect of other substances, chiefly nonmedicinal as to source
 Injuries & Poisonings 0.896 0.724 – 1.11 0.314 89 890 all phecode
990 Effects radiation NOS Injuries & Poisonings 1.12 1.08 – 1.16 3.59e-09 3113 31140 all phecode
994 Sepsis and SIRS Injuries & Poisonings 1.22 1.18 – 1.27 1.11e-27 3028 30268 all phecode
994.2 Sepsis Injuries & Poisonings 1.22 1.18 – 1.27 1.11e-27 3028 30268 all phecode
008 Intestinal infection Infectious Diseases 1.09 1.06 – 1.12 3.41e-13 7801 83500 exclusion phecode
008.5 Bacterial enteritis Infectious Diseases 1.11 1.07 – 1.16 2.93e-07 2432 25627 exclusion phecode
008.52 Intestinal infection due to C. difficile Infectious Diseases 1.11 1.02 – 1.21 0.0145 575 6126 exclusion phecode
008.6 Viral Enteritis Infectious Diseases 1.09 1.01 – 1.17 0.0287 743 8128 exclusion phecode
008.7 Intestinal infection due to protozoa Infectious Diseases 1.22 0.938 – 1.58 0.139 53 526 exclusion phecode
010 Tuberculosis Infectious Diseases 0.986 0.834 – 1.17 0.87 154 1538 exclusion phecode
038 Septicemia Infectious Diseases 1.11 1.07 – 1.14 5.59e-09 3616 39127 exclusion phecode
038.1 Gram negative septicemia Infectious Diseases 1.08 1.01 – 1.17 0.0364 733 7938 exclusion phecode
038.2 Gram positive septicemia Infectious Diseases 1.1 0.998 – 1.22 0.0556 413 4672 exclusion phecode
041 Bacterial infection NOS Infectious Diseases 1.13 1.11 – 1.16 3.32e-34 10505 113294 exclusion phecode
041.1 Staphylococcus infections Infectious Diseases 1.16 1.11 – 1.2 9.25e-13 2641 29478 exclusion phecode
041.2 Streptococcus infection Infectious Diseases 1.14 1.08 – 1.2 1.96e-06 1436 15459 exclusion phecode
041.4 E. coli Infectious Diseases 1.14 1.09 – 1.19 1.1e-09 2350 25798 exclusion phecode
053 Herpes zoster Infectious Diseases 1.15 1.03 – 1.28 0.0104 370 3849 exclusion phecode
053.1 Herpes zoster with nervous system complications Infectious Diseases 1.28 1.02 – 1.6 0.0318 87 886 exclusion phecode
054 Herpes simplex Infectious Diseases 1.02 0.875 – 1.18 0.842 200 1993 exclusion phecode
070 Viral hepatitis Infectious Diseases 1.05 0.962 – 1.15 0.271 527 5587 exclusion phecode
070.1 Viral hepatitis A Infectious Diseases 1.19 0.924 – 1.54 0.175 63 653 exclusion phecode
070.2 Viral hepatitis B Infectious Diseases 1.02 0.849 – 1.24 0.8 118 1254 exclusion phecode
070.3 Viral hepatitis C Infectious Diseases 1.05 0.922 – 1.2 0.444 234 2444 exclusion phecode
070.4 Chronic hepatitis Infectious Diseases 1.12 0.986 – 1.28 0.081 243 2621 exclusion phecode
070.9 Hepatitis NOS Infectious Diseases 1.26 1.13 – 1.41 4.41e-05 317 4032 exclusion phecode
071 Human immunodeficiency virus [HIV] disease Infectious Diseases 0.979 0.821 – 1.17 0.816 137 1384 exclusion phecode
071.1 HIV infection, symptomatic Infectious Diseases 0.96 0.787 – 1.17 0.69 107 1090 exclusion phecode
078 Viral warts & HPV Infectious Diseases 1.09 1.02 – 1.17 0.00792 927 9515 exclusion phecode
079 Viral infection Infectious Diseases 1.05 1.01 – 1.09 0.0199 2526 26371 exclusion phecode
079.1 Varicella infection Infectious Diseases 1.09 0.83 – 1.42 0.545 61 613 exclusion phecode
080 Postoperative infection Infectious Diseases 1.14 1.1 – 1.18 7.41e-15 3928 42268 exclusion phecode
081
Infection/inflammation of internal prosthetic
Infection/inflammation of internal prosthetic device; implant; and graft
 Infectious Diseases 1.11 1.06 – 1.16 3.32e-06 2215 23313 exclusion phecode
090
Sexually transmitted infections (not HIV or
Sexually transmitted infections (not HIV or hepatitis)
 Infectious Diseases 1.05 0.802 – 1.36 0.744 60 662 exclusion phecode
1000 Burns Injuries & Poisonings 1.06 0.966 – 1.16 0.233 527 5463 exclusion phecode
1001 Foreign body injury Injuries & Poisonings 1.05 0.985 – 1.11 0.14 1110 11318 exclusion phecode
1002
Symptoms concerning nutrition, metabolism, and
Symptoms concerning nutrition, metabolism, and development
 Injuries & Poisonings 1.06 1.03 – 1.1 2.27e-05 4996 51572 exclusion phecode
1004
Other signs and symptoms involving emotional
Other signs and symptoms involving emotional state
 Injuries & Poisonings 1.12 0.984 – 1.27 0.0861 265 2835 exclusion phecode
1005 Other symptoms Injuries & Poisonings 1.14 1.07 – 1.2 8.07e-06 1294 13556 exclusion phecode
1006 Crushing injury Injuries & Poisonings 0.934 0.817 – 1.07 0.314 237 2403 exclusion phecode
1007 Injury to blood vessels Injuries & Poisonings 1.04 0.912 – 1.19 0.55 236 2392 exclusion phecode
1008 Crushing or internal injury to organs Injuries & Poisonings 0.994 0.93 – 1.06 0.87 944 9490 exclusion phecode
1009 Injury, NOS Injuries & Poisonings 1.08 1.05 – 1.1 1.01e-09 7818 80029 exclusion phecode
1010 Other tests Injuries & Poisonings 1.11 1.07 – 1.14 3.81e-12 5217 55996 exclusion phecode
1011 Complications of surgical and medical procedures Injuries & Poisonings 1.12 1.1 – 1.15 2.26e-23 8339 85978 exclusion phecode
1012 Late effect Injuries & Poisonings 1.12 0.912 – 1.38 0.275 95 998 exclusion phecode
1013 Asphyxia and hypoxemia Injuries & Poisonings 1.08 0.955 – 1.22 0.217 283 2995 exclusion phecode
1014 Effects of heat, cold and air pressure Injuries & Poisonings 1.13 0.872 – 1.46 0.358 62 622 exclusion phecode
1015 Effects of other external causes Injuries & Poisonings 1.1 1.06 – 1.13 5.07e-08 3770 40032 exclusion phecode
1019
Other ill-defined and unknown causes of
Other ill-defined and unknown causes of morbidity and mortality
 Injuries & Poisonings 1.09 1.07 – 1.11 8.19e-22 14592 150541 exclusion phecode
110 Dermatophytosis / Dermatomycosis Infectious Diseases 1.14 1 – 1.3 0.0477 252 2617 exclusion phecode
110.1 Dermatophytosis Infectious Diseases 1.15 1 – 1.31 0.0432 247 2562 exclusion phecode
110.11 Dermatophytosis of nail Infectious Diseases 1.12 0.881 – 1.43 0.353 72 708 exclusion phecode
110.12 Althete's foot Infectious Diseases 1.07 0.882 – 1.29 0.507 126 1320 exclusion phecode
112 Candidiasis Infectious Diseases 1.12 1.07 – 1.18 9.94e-07 1898 19991 exclusion phecode
117 Mycoses Infectious Diseases 1.17 1.03 – 1.33 0.0192 248 2530 exclusion phecode
117.4 Aspergillosis Infectious Diseases 1.1 0.927 – 1.3 0.282 151 1525 exclusion phecode
130 Spirochetal infection Infectious Diseases 0.88 0.701 – 1.1 0.27 79 764 exclusion phecode
133 Arthropod-borne diseases Infectious Diseases 0.974 0.747 – 1.27 0.843 64 644 exclusion phecode
134 Helminthiases Infectious Diseases 1.12 0.925 – 1.35 0.247 119 1222 exclusion phecode
134.1 Intestinal helminthiases Infectious Diseases 1.07 0.866 – 1.31 0.545 99 1022 exclusion phecode
136 Other infectious and parasitic diseases Infectious Diseases 1.21 1.04 – 1.4 0.0133 189 1924 exclusion phecode
145 Cancer of mouth Neoplasms 1.07 0.98 – 1.16 0.134 608 5992 exclusion phecode
145.2 Cancer of tongue Neoplasms 1.06 0.941 – 1.2 0.332 292 2888 exclusion phecode
145.3 Cancer of major salivary glands Neoplasms 1.17 0.954 – 1.43 0.132 104 996 exclusion phecode
145.5 Cancer of the mouth floor Neoplasms 0.855 0.632 – 1.16 0.31 49 502 exclusion phecode
149 Cancer of larynx, pharynx, nasal cavities Neoplasms 1.16 1.07 – 1.26 0.000661 572 5872 exclusion phecode
149.1 Cancer of oropharynx Neoplasms 1.24 1.08 – 1.41 0.00206 229 2341 exclusion phecode
149.4 Cancer of larynx Neoplasms 1.11 0.974 – 1.27 0.114 231 2424 exclusion phecode
149.9 Cancer of of nasal cavities Neoplasms 1.09 0.831 – 1.43 0.528 55 543 exclusion phecode
150 Cancer of esophagus Neoplasms 1.04 0.96 – 1.13 0.338 676 7038 exclusion phecode
151 Cancer of stomach Neoplasms 1.1 1.01 – 1.21 0.0378 504 5252 exclusion phecode
153 Colorectal cancer Neoplasms 1.04 1 – 1.07 0.0304 4216 42788 exclusion phecode
153.2 Colon cancer Neoplasms 1.04 1 – 1.08 0.0359 2858 28989 exclusion phecode
153.3
Malignant neoplasm of rectum, rectosigmoid
Malignant neoplasm of rectum, rectosigmoid junction, and anus
 Neoplasms 1.01 0.968 – 1.06 0.571 1984 20217 exclusion phecode
155 Cancer of liver and intrahepatic bile duct Neoplasms 1.18 1.06 – 1.32 0.00315 327 3715 exclusion phecode
155.1 Malignant neoplasm of liver, primary Neoplasms 1.16 0.966 – 1.4 0.111 114 1454 exclusion phecode
157 Pancreatic cancer Neoplasms 1.24 1.14 – 1.34 6.26e-07 576 6096 exclusion phecode
158
Neoplasm of unspecified nature of digestive
Neoplasm of unspecified nature of digestive system
 Neoplasms 1.04 0.974 – 1.11 0.245 967 9951 exclusion phecode
159
Malignant neoplasm of other and ill-defined
Malignant neoplasm of other and ill-defined sites within the digestive organs and peritoneum
 Neoplasms 1.05 1.02 – 1.08 7e-04 5079 51987 exclusion phecode
159.2
Malignant neoplasm of small intestine
Malignant neoplasm of small intestine, including duodenum
 Neoplasms 1.09 0.934 – 1.27 0.272 172 1773 exclusion phecode
159.3
Malignant neoplasm of gallbladder and
Malignant neoplasm of gallbladder and extrahepatic bile ducts
 Neoplasms 1.12 0.966 – 1.3 0.132 183 1911 exclusion phecode
159.4
Malignant neoplasm of retroperitoneum and
Malignant neoplasm of retroperitoneum and peritoneum
 Neoplasms 1.12 0.959 – 1.3 0.154 177 1800 exclusion phecode
164 Cancer of intrathoracic organs Neoplasms 1.09 0.826 – 1.44 0.545 56 562 exclusion phecode
165 Cancer within the respiratory system Neoplasms 1.12 1.08 – 1.17 1.62e-08 2559 26211 exclusion phecode
165.1 Cancer of bronchus; lung Neoplasms 1.12 1.07 – 1.17 1.62e-06 2019 20736 exclusion phecode
170 Cancer of bone and connective tissue Neoplasms 0.961 0.868 – 1.06 0.439 407 4098 exclusion phecode
170.1 Bone cancer Neoplasms 0.912 0.763 – 1.09 0.313 123 1237 exclusion phecode
170.2 Cancer of connective tissue Neoplasms 1 0.891 – 1.13 0.975 308 3112 exclusion phecode
172 Skin cancer Neoplasms 0.996 0.978 – 1.01 0.699 12674 126217 exclusion phecode
172.1 Melanomas of skin, dx or hx Neoplasms 0.962 0.923 – 1 0.0614 2538 25249 exclusion phecode
172.11 Melanomas of skin Neoplasms 0.963 0.925 – 1 0.073 2568 25565 exclusion phecode
172.2 Other non-epithelial cancer of skin Neoplasms 0.997 0.977 – 1.02 0.809 10324 102723 exclusion phecode
172.3 Carcinoma in situ of skin Neoplasms 1 0.922 – 1.08 0.994 617 6227 exclusion phecode
173 Neoplasm of uncertain behavior of skin Neoplasms 0.949 0.812 – 1.11 0.507 169 1726 exclusion phecode
174 Breast cancer Neoplasms 1.01 0.988 – 1.03 0.511 12089 121554 exclusion phecode
174.1 Breast cancer [female] Neoplasms 1.01 0.988 – 1.03 0.468 11895 119587 exclusion phecode
174.11 Malignant neoplasm of female breast Neoplasms 1.01 0.989 – 1.03 0.401 11201 112851 exclusion phecode
174.3 Neoplasm of uncertain behavior of breast Neoplasms 1.18 0.968 – 1.43 0.102 109 1103 exclusion phecode
175 Acquired absence of breast Neoplasms 0.999 0.956 – 1.04 0.967 2267 23059 exclusion phecode
180 Cervical cancer and dysplasia Neoplasms 1.01 0.962 – 1.05 0.792 2101 21052 exclusion phecode
180.1 Cervical cancer Neoplasms 0.914 0.806 – 1.04 0.162 263 2628 exclusion phecode
180.3
Cervical intraepithelial neoplasia [CIN]
Cervical intraepithelial neoplasia [CIN] [Cervical dysplasia]
 Neoplasms 1.01 0.968 – 1.06 0.552 2006 20110 exclusion phecode
182 Malignant neoplasm of uterus Neoplasms 1.05 0.99 – 1.12 0.101 1172 12252 exclusion phecode
184 Cancer of other female genital organs Neoplasms 1.07 1.01 – 1.13 0.0215 1317 13206 exclusion phecode
184.1
Malignant neoplasm of ovary and other uterine
Malignant neoplasm of ovary and other uterine adnexa
 Neoplasms 1.07 0.998 – 1.14 0.0567 926 9253 exclusion phecode
184.11 Malignant neoplasm of ovary Neoplasms 1.08 1.01 – 1.16 0.032 899 8989 exclusion phecode
184.2
Cancer of other female genital organs
Cancer of other female genital organs (excluding uterus and ovary)
 Neoplasms 1.1 0.976 – 1.24 0.116 292 2931 exclusion phecode
185 Cancer of prostate Neoplasms 1.04 1.01 – 1.07 0.00747 5561 53416 exclusion phecode
187 Cancer of other male genital organs Neoplasms 0.94 0.85 – 1.04 0.235 409 4176 exclusion phecode
187.1
Malignant neoplasm of unspecified male genital
Malignant neoplasm of unspecified male genital organ
 Neoplasms 0.965 0.745 – 1.25 0.79 61 652 exclusion phecode
187.2 Malignant neoplasm of testis Neoplasms 0.933 0.823 – 1.06 0.274 262 2693 exclusion phecode
187.8
Neoplasm of uncertain behavior of male genital
Neoplasm of uncertain behavior of male genital organs
 Neoplasms 1 0.809 – 1.24 0.982 101 1018 exclusion phecode
189
Cancer of urinary organs (incl. kidney and
Cancer of urinary organs (incl. kidney and bladder)
 Neoplasms 1.07 1.04 – 1.11 2.97e-05 3716 38439 exclusion phecode
189.1 Cancer of kidney and renal pelvis Neoplasms 1.09 1.02 – 1.17 0.00935 964 10024 exclusion phecode
189.11 Malignant neoplasm of kidney, except pelvis Neoplasms 1.1 1.03 – 1.18 0.00462 924 9659 exclusion phecode
189.12 Malignant neoplasm of renal pelvis Neoplasms 1.02 0.793 – 1.3 0.897 62 608 exclusion phecode
189.2 Cancer of bladder Neoplasms 1.07 1.02 – 1.11 0.00408 2133 22199 exclusion phecode
189.21 Malignant neoplasm of bladder Neoplasms 1.09 1.04 – 1.14 0.00041 1895 19748 exclusion phecode
189.4 Malignant neoplasm of other urinary organs Neoplasms 1.06 0.891 – 1.27 0.491 134 1315 exclusion phecode
190 Cancer of eye Neoplasms 1.04 0.889 – 1.22 0.617 161 1637 exclusion phecode
191
Manlignant and unknown neoplasms of brain and
Manlignant and unknown neoplasms of brain and nervous system
 Neoplasms 1.05 0.974 – 1.14 0.192 649 6455 exclusion phecode
191.1 Cancer of brain and nervous system Neoplasms 1.04 0.952 – 1.14 0.384 536 5303 exclusion phecode
191.11 Cancer of brain Neoplasms 1.03 0.937 – 1.12 0.578 498 4914 exclusion phecode
193 Thyroid cancer Neoplasms 0.975 0.871 – 1.09 0.667 320 3328 exclusion phecode
194 Cancer of other endocrine glands Neoplasms 1.01 0.797 – 1.27 0.961 81 896 exclusion phecode
195 Cancer, suspected or other Neoplasms 1.06 1.04 – 1.08 2.42e-11 15717 155208 exclusion phecode
195.1 Malignant neoplasm, other Neoplasms 1.06 1.04 – 1.07 1.11e-10 15068 149539 exclusion phecode
197 Chemotherapy Neoplasms 1.08 1.07 – 1.1 3.33e-27 19777 201681 exclusion phecode
198 Secondary malignant neoplasm Neoplasms 1.07 1.05 – 1.09 9.95e-10 8818 89754 exclusion phecode
198.1 Secondary malignancy of lymph nodes Neoplasms 1.04 1.01 – 1.07 0.00612 4996 50682 exclusion phecode
198.2 Secondary malignancy of respiratory organs Neoplasms 1.08 1.03 – 1.13 0.00075 2085 21259 exclusion phecode
198.3
Secondary malignant neoplasm of digestive
Secondary malignant neoplasm of digestive systems
 Neoplasms 1.06 0.999 – 1.11 0.053 1433 14603 exclusion phecode
198.4 Secondary malignant neoplasm of liver Neoplasms 1.07 1.03 – 1.11 0.00152 2439 24960 exclusion phecode
198.5 Secondary malignancy of brain/spine Neoplasms 1.05 0.974 – 1.13 0.208 798 7968 exclusion phecode
198.6 Secondary malignancy of bone Neoplasms 1.07 1.02 – 1.12 0.00339 1979 20192 exclusion phecode
198.7 Secondary malignant neoplasm of skin Neoplasms 1.17 1 – 1.37 0.0506 174 1775 exclusion phecode
199 Neoplasm of uncertain behavior Neoplasms 1.08 1.02 – 1.14 0.00979 1319 13484 exclusion phecode
199.4 Neurofibromatosis Neoplasms 1.03 0.833 – 1.27 0.8 91 905 exclusion phecode
200 Myeloproliferative disease Neoplasms 1.12 1.05 – 1.2 0.000793 889 9257 exclusion phecode
200.1 Polycythemia vera Neoplasms 1.12 1 – 1.26 0.0433 331 3575 exclusion phecode
201 Hodgkin's disease Neoplasms 0.933 0.819 – 1.06 0.3 240 2447 exclusion phecode
202 Cancer of other lymphoid, histiocytic tissue Neoplasms 1.03 0.985 – 1.08 0.193 2095 21255 exclusion phecode
202.2 Non-Hodgkins lymphoma Neoplasms 1.01 0.959 – 1.06 0.758 1669 16881 exclusion phecode
202.21 Nodular lymphoma Neoplasms 0.957 0.856 – 1.07 0.437 340 3414 exclusion phecode
202.24 Large cell lymphoma Neoplasms 1.07 0.976 – 1.17 0.157 538 5448 exclusion phecode
204 Leukemia Neoplasms 1.08 1.02 – 1.13 0.00691 1528 15471 exclusion phecode
204.1 Lymphoid leukemia Neoplasms 1.02 0.933 – 1.11 0.668 521 5374 exclusion phecode
204.11 Lymphoid leukemia, acute Neoplasms 1.31 0.993 – 1.74 0.0563 52 529 exclusion phecode
204.12 Lymphoid leukemia, chronic Neoplasms 0.988 0.898 – 1.09 0.802 453 4700 exclusion phecode
204.2 Myeloid leukemia Neoplasms 1.09 0.988 – 1.21 0.0856 436 4302 exclusion phecode
204.21 Myeloid leukemia, acute Neoplasms 1.07 0.949 – 1.21 0.271 311 3041 exclusion phecode
204.22 Myeloid leukemia, chronic Neoplasms 1.08 0.904 – 1.3 0.388 137 1359 exclusion phecode
204.4 Multiple myeloma Neoplasms 1.06 0.97 – 1.16 0.195 517 5179 exclusion phecode
208 Benign neoplasm of colon Neoplasms 1.08 1.06 – 1.1 4.24e-22 18008 180018 exclusion phecode
210 Benign neoplasm of lip, oral cavity, and pharynx Neoplasms 1.05 0.984 – 1.13 0.136 901 9212 exclusion phecode
211
Benign neoplasm of other parts of digestive
Benign neoplasm of other parts of digestive system
 Neoplasms 1.07 1.04 – 1.1 7.73e-06 4765 49410 exclusion phecode
212
Benign neoplasm of respiratory and
Benign neoplasm of respiratory and intrathoracic organs
 Neoplasms 1.08 0.961 – 1.21 0.199 319 3256 exclusion phecode
213 Benign neoplasm of bone and articular cartilage Neoplasms 1.04 0.93 – 1.17 0.464 304 3023 exclusion phecode
214 Lipoma Neoplasms 1.06 1.03 – 1.08 9.23e-05 5824 58607 exclusion phecode
214.1 Lipoma of skin and subcutaneous tissue Neoplasms 1.05 1.02 – 1.08 0.00271 4307 43303 exclusion phecode
215
Other benign neoplasm of connective and other
Other benign neoplasm of connective and other soft tissue
 Neoplasms 1.03 0.965 – 1.09 0.39 1055 10460 exclusion phecode
216 Benign neoplasm of skin Neoplasms 1.02 0.996 – 1.05 0.11 7257 72741 exclusion phecode
217 Vascular hamartomas and non-neoplastic nevi Neoplasms 1.07 0.985 – 1.17 0.106 587 5954 exclusion phecode
217.1 Nevus, non-neoplastic Neoplasms 1.08 0.994 – 1.18 0.0682 551 5598 exclusion phecode
218 Benign neoplasm of uterus Neoplasms 1.05 1.03 – 1.07 4.33e-06 9606 96769 exclusion phecode
218.1 Uterine leiomyoma Neoplasms 1.05 1.03 – 1.07 1.38e-05 9813 98814 exclusion phecode
218.2 Other benign neoplasm of uterus Neoplasms 1.01 0.901 – 1.13 0.876 336 3427 exclusion phecode
220 Benign neoplasm of ovary Neoplasms 1.04 0.987 – 1.1 0.13 1358 13942 exclusion phecode
221 Benign neoplasm of other female genital organs Neoplasms 1.02 0.881 – 1.17 0.822 200 2113 exclusion phecode
222 Benign neoplasm of male genital organs Neoplasms 1.09 0.917 – 1.28 0.341 148 1462 exclusion phecode
223
Benign neoplasm of kidney and other urinary
Benign neoplasm of kidney and other urinary organs
 Neoplasms 1.37 1.16 – 1.62 0.000184 156 1600 exclusion phecode
224 Benign neoplasm of eye Neoplasms 1.03 0.853 – 1.25 0.75 114 1213 exclusion phecode
224.1 Benign neoplasm of eye, uveal Neoplasms 1.02 0.785 – 1.33 0.873 56 632 exclusion phecode
225
Benign neoplasm of brain and other parts of
Benign neoplasm of brain and other parts of nervous system
 Neoplasms 1.1 1.02 – 1.19 0.0106 765 7697 exclusion phecode
225.1
Benign neoplasm of brain, cranial nerves
Benign neoplasm of brain, cranial nerves, meninges
 Neoplasms 1.09 1.01 – 1.18 0.0223 726 7322 exclusion phecode
225.2 Benign neoplasm of spinal cord, meninges Neoplasms 1.28 0.97 – 1.69 0.0805 55 565 exclusion phecode
226 Benign neoplasm of thyroid glands Neoplasms 1.06 0.935 – 1.21 0.348 251 2537 exclusion phecode
227
Benign neoplasm of other endocrine glands and
Benign neoplasm of other endocrine glands and related structures
 Neoplasms 1.07 0.99 – 1.15 0.0896 757 8145 exclusion phecode
227.1 Benign neoplasm of adrenal gland Neoplasms 1.12 0.948 – 1.31 0.188 153 1741 exclusion phecode
227.2 Benign neoplasm of parathyroid gland Neoplasms 0.994 0.889 – 1.11 0.923 338 3497 exclusion phecode
227.3
Benign neoplasm of pituitary gland and
Benign neoplasm of pituitary gland and craniopharyngeal duct (pouch)
 Neoplasms 1.15 1.02 – 1.3 0.0261 272 2944 exclusion phecode
228 Hemangioma and lymphangioma, any site Neoplasms 1.04 0.988 – 1.1 0.135 1494 15077 exclusion phecode
229 Benign neoplasm of unspecified sites Neoplasms 1.04 0.992 – 1.08 0.109 2281 22844 exclusion phecode
240 Simple and unspecified goiter Endocrine/metabolic 1.12 1.03 – 1.23 0.0109 554 5744 exclusion phecode
241 Nontoxic nodular goiter Endocrine/metabolic 1.09 1.02 – 1.16 0.0109 1055 10605 exclusion phecode
241.1 Nontoxic uninodular goiter Endocrine/metabolic 1.09 0.989 – 1.2 0.0814 453 4518 exclusion phecode
241.2 Nontoxic multinodular goiter Endocrine/metabolic 1.06 0.973 – 1.15 0.187 641 6466 exclusion phecode
242 Thyrotoxicosis with or without goiter Endocrine/metabolic 1.13 1.08 – 1.19 1.24e-06 1673 17648 exclusion phecode
242.1 Graves' disease Endocrine/metabolic 1.15 1.04 – 1.27 0.00727 418 4347 exclusion phecode
242.2 Toxic multinodular goiter Endocrine/metabolic 1.05 0.84 – 1.32 0.649 86 869 exclusion phecode
242.3 Exophthalmos Endocrine/metabolic 1.35 1.12 – 1.63 0.00145 126 1301 exclusion phecode
244 Hypothyroidism Endocrine/metabolic 1.12 1.1 – 1.14 6.7e-37 13227 138345 exclusion phecode
244.1 Secondary hypothyroidism Endocrine/metabolic 1.13 1.06 – 1.2 0.000293 1001 10545 exclusion phecode
244.2 Acquired hypothyroidism Endocrine/metabolic 1.18 0.955 – 1.47 0.124 87 957 exclusion phecode
244.4 Hypothyroidism NOS Endocrine/metabolic 1.12 1.1 – 1.14 1.48e-35 12609 132481 exclusion phecode
245 Thyroiditis Endocrine/metabolic 1.07 0.944 – 1.21 0.298 272 2761 exclusion phecode
245.2 Chronic thyroiditis Endocrine/metabolic 1.13 0.98 – 1.31 0.0911 206 2085 exclusion phecode
245.21 Chronic lymphocytic thyroiditis Endocrine/metabolic 1.15 0.995 – 1.34 0.0577 201 2015 exclusion phecode
246 Other disorders of thyroid Endocrine/metabolic 1.18 1.06 – 1.31 0.0027 371 3790 exclusion phecode
250 Diabetes mellitus Endocrine/metabolic 4.5 4.37 – 4.64 2.98e-2006 5756 181935 exclusion phecode
250.1 Type 1 diabetes Endocrine/metabolic 2.36 2.03 – 2.75 4.13e-29 172 27032 exclusion phecode
250.11 Type 1 diabetes with ketoacidosis Endocrine/metabolic 2.86 1.68 – 4.85 0.000103 12 2342 exclusion phecode
250.12 Type 1 diabetes with renal manifestations Endocrine/metabolic 2.9 1.03 – 8.18 0.0434 1 750 exclusion phecode
250.13 Type 1 diabetes with ophthalmic manifestations Endocrine/metabolic 1.36 0.712 – 2.58 0.354 6 4637 exclusion phecode
250.14 Type 1 diabetes with neurological manifestations Endocrine/metabolic 1.09 0.519 – 2.27 0.827 3 1587 exclusion phecode
250.2 Type 2 diabetes Endocrine/metabolic 6.05 5.83 – 6.28 1.56e-2000 4878 166402 exclusion phecode
250.21 Type 2 diabetes with ketoacidosis Endocrine/metabolic 4.74 2.51 – 8.93 1.5e-06 12 1018 exclusion phecode
250.22 Type 2 diabetes with renal manifestations Endocrine/metabolic 4.48 2.46 – 8.16 9.96e-07 10 1969 exclusion phecode
250.23 Type 2 diabetes with ophthalmic manifestations Endocrine/metabolic 6.22 4.46 – 8.68 4.32e-27 46 9635 exclusion phecode
250.24 Type 2 diabetes with neurological manifestations Endocrine/metabolic 6.81 4.24 – 10.9 1.88e-15 21 4949 exclusion phecode
250.4 Abnormal glucose Endocrine/metabolic 1.56 1.41 – 1.72 3.91e-18 423 6683 exclusion phecode
250.41 Impaired fasting glucose Endocrine/metabolic 1.57 1.35 – 1.82 2.83e-09 186 2598 exclusion phecode
250.42 Other abnormal glucose Endocrine/metabolic 1.57 1.37 – 1.79 3.33e-11 240 4099 exclusion phecode
250.5 Glycosuria or Acetonuria Endocrine/metabolic 1.4 1.13 – 1.74 0.00205 93 1287 exclusion phecode
250.6 Polyneuropathy in diabetes Endocrine/metabolic 4.59 2.76 – 7.64 4.67e-09 14 3419 exclusion phecode
250.7 Diabetic retinopathy Endocrine/metabolic 2.18 1.77 – 2.68 3.2e-13 76 12416 exclusion phecode
251.1 Hypoglycemia Endocrine/metabolic 1.54 1.36 – 1.75 5.87e-12 272 9153 exclusion phecode
252 Disorders of parathyroid gland Endocrine/metabolic 1.07 0.993 – 1.15 0.0768 768 8265 exclusion phecode
252.1 Hyperparathyroidism Endocrine/metabolic 1.07 0.987 – 1.15 0.105 685 7393 exclusion phecode
252.2 Hypoparathyroidism Endocrine/metabolic 1.28 1.07 – 1.54 0.00676 124 1345 exclusion phecode
253
Disorders of the pituitary gland and its
Disorders of the pituitary gland and its hypothalamic control
 Endocrine/metabolic 1.2 1.1 – 1.31 2.92e-05 585 6425 exclusion phecode
253.1 Pituitary hyperfunction Endocrine/metabolic 1.23 1.04 – 1.45 0.0142 162 1772 exclusion phecode
253.11 Acromegaly and gigantism Endocrine/metabolic 1.34 1.06 – 1.69 0.0133 82 901 exclusion phecode
253.2 Pituitary hypofunction Endocrine/metabolic 1.15 1 – 1.32 0.0443 216 2443 exclusion phecode
253.3 Diabetes insipidus Endocrine/metabolic 1.72 1.34 – 2.2 2.09e-05 70 868 exclusion phecode
253.7 Other disorders of neurohypophysis Endocrine/metabolic 1.03 0.863 – 1.23 0.754 137 1477 exclusion phecode
255 Disorders of adrenal glands Endocrine/metabolic 1.21 1.11 – 1.32 2.88e-05 539 6034 exclusion phecode
255.1 Adrenal hyperfunction Endocrine/metabolic 1.27 1.07 – 1.5 0.00666 142 1704 exclusion phecode
255.11 Cushing's syndrome Endocrine/metabolic 1.22 0.976 – 1.53 0.0805 79 984 exclusion phecode
255.12 Hyperaldosteronism Endocrine/metabolic 1.29 0.995 – 1.66 0.0547 62 724 exclusion phecode
255.2 Adrenal hypofunction Endocrine/metabolic 1.18 1.05 – 1.33 0.00562 310 3436 exclusion phecode
255.21 Glucocorticoid deficiency Endocrine/metabolic 1.17 1.04 – 1.31 0.00847 309 3426 exclusion phecode
256 Ovarian dysfunction Endocrine/metabolic 1.22 1.07 – 1.4 0.00368 223 2355 exclusion phecode
256.4 Polycystic ovaries Endocrine/metabolic 1.2 1.04 – 1.39 0.0153 192 2054 exclusion phecode
257 Testicular dysfunction Endocrine/metabolic 1.18 0.991 – 1.41 0.0624 134 1510 exclusion phecode
257.1 Testicular hypofunction Endocrine/metabolic 1.24 1.04 – 1.48 0.0193 125 1437 exclusion phecode
258 Iatrogenic endocrine disorders Endocrine/metabolic 1.11 0.883 – 1.4 0.367 80 958 exclusion phecode
259 Other endocrine disorders Endocrine/metabolic 1.27 1.07 – 1.5 0.00717 133 1439 exclusion phecode
260 Protein-calorie malnutrition Endocrine/metabolic 1.05 0.906 – 1.21 0.533 185 1908 exclusion phecode
260.1 Cachexia Endocrine/metabolic 1.09 0.821 – 1.44 0.562 46 478 exclusion phecode
260.6 Anorexia Endocrine/metabolic 1.06 0.987 – 1.15 0.105 754 7811 exclusion phecode
261 Vitamin deficiency Endocrine/metabolic 1.1 1.03 – 1.17 0.00327 1030 11349 exclusion phecode
261.2 Vitamin B-complex deficiencies Endocrine/metabolic 1.11 1.02 – 1.2 0.0146 646 7125 exclusion phecode
261.4 Vitamin D deficiency Endocrine/metabolic 1.11 1 – 1.24 0.0419 387 4256 exclusion phecode
261.41 Rickets or osteomalacia Endocrine/metabolic 1.07 0.85 – 1.35 0.559 71 738 exclusion phecode
262 Mineral deficiency NEC Endocrine/metabolic 1.09 0.944 – 1.25 0.249 216 2262 exclusion phecode
269 Proteinuria Endocrine/metabolic 1.22 1.08 – 1.38 0.000994 278 3150 exclusion phecode
270
Disorders of protein plasma/amino-acid
Disorders of protein plasma/amino-acid transport and metabolism
 Endocrine/metabolic 0.996 0.878 – 1.13 0.947 265 2832 exclusion phecode
270.3 Disorders of plasma protein metabolism Endocrine/metabolic 0.988 0.863 – 1.13 0.856 232 2426 exclusion phecode
270.32 Paraproteinemia Endocrine/metabolic 1.1 0.935 – 1.29 0.255 164 1769 exclusion phecode
270.33 Amyloidosis Endocrine/metabolic 1.07 0.875 – 1.3 0.527 104 1061 exclusion phecode
270.35 Macroglobulinemia Endocrine/metabolic 0.737 0.571 – 0.952 0.0193 67 646 exclusion phecode
271
Disorders of carbohydrate transport and
Disorders of carbohydrate transport and metabolism
 Endocrine/metabolic 1.2 1 – 1.44 0.0465 130 1523 exclusion phecode
271.3
Intestinal disaccharidase deficiencies and
Intestinal disaccharidase deficiencies and disaccharide malabsorption
 Endocrine/metabolic 1.1 0.91 – 1.33 0.319 116 1326 exclusion phecode
272 Disorders of lipoid metabolism Endocrine/metabolic 1.2 1.18 – 1.21 3.52e-181 28950 224168 exclusion phecode
272.1 Hyperlipidemia Endocrine/metabolic 1.2 1.18 – 1.21 2.95e-181 28885 223940 exclusion phecode
272.11 Hypercholesterolemia Endocrine/metabolic 1.2 1.19 – 1.22 5.7e-173 26890 217030 exclusion phecode
272.12 Hyperglyceridemia Endocrine/metabolic 1.48 1.1 – 1.97 0.00868 47 554 exclusion phecode
272.13 Mixed hyperlipidemia Endocrine/metabolic 1.3 1.08 – 1.57 0.00493 120 1555 exclusion phecode
272.9 Unspecified disorder of lipoid metabolism Endocrine/metabolic 1.22 1.04 – 1.43 0.0129 161 1985 exclusion phecode
274 Gout and other crystal arthropathies Endocrine/metabolic 1.26 1.21 – 1.3 3.32e-35 3155 34506 exclusion phecode
274.1 Gout Endocrine/metabolic 1.27 1.22 – 1.32 6.96e-33 2649 29328 exclusion phecode
274.11 Gouty arthropathy Endocrine/metabolic 1.35 1.1 – 1.66 0.00357 94 1039 exclusion phecode
274.2 Crystal arthropathies Endocrine/metabolic 1.18 1.08 – 1.29 0.000185 556 5758 exclusion phecode
274.21 Chondrocalcinosis Endocrine/metabolic 1.19 1.09 – 1.3 0.000189 513 5241 exclusion phecode
275 Disorders of mineral metabolism Endocrine/metabolic 1.11 1.06 – 1.16 1.91e-05 1840 19677 exclusion phecode
275.1 Disorders of iron metabolism Hematopoietic 1.02 0.94 – 1.11 0.607 577 6082 exclusion phecode
275.3 Disorders of magnesium metabolism Endocrine/metabolic 1.2 1.07 – 1.35 0.00231 308 3509 exclusion phecode
275.5 Disorders of calcium/phosphorus metabolism Endocrine/metabolic 1.15 1.08 – 1.23 1.31e-05 1055 11243 exclusion phecode
275.53 Disorders of phosphorus metabolism Endocrine/metabolic 1.28 1.08 – 1.52 0.00376 151 1592 exclusion phecode
276
Disorders of fluid, electrolyte, and acid-base
Disorders of fluid, electrolyte, and acid-base balance
 Endocrine/metabolic 1.15 1.12 – 1.18 9.9e-25 6025 68192 exclusion phecode
276.1 Electrolyte imbalance Endocrine/metabolic 1.13 1.09 – 1.17 2.19e-12 3363 38240 exclusion phecode
276.11 Hyperosmolality and/or hypernatremia Endocrine/metabolic 1.25 1.08 – 1.46 0.00303 186 2236 exclusion phecode
276.12 Hyposmolality and/or hyponatremia Endocrine/metabolic 1.1 1.05 – 1.16 0.000209 1580 17053 exclusion phecode
276.13 Hyperpotassemia Endocrine/metabolic 1.19 1.1 – 1.29 1.24e-05 644 9010 exclusion phecode
276.14 Hypopotassemia Endocrine/metabolic 1.12 1.06 – 1.19 9.36e-05 1250 13379 exclusion phecode
276.4 Acid-base balance disorder Endocrine/metabolic 1.18 1.1 – 1.27 1.45e-06 906 10866 exclusion phecode
276.41 Acidosis Endocrine/metabolic 1.19 1.11 – 1.28 2.33e-06 813 9862 exclusion phecode
276.42 Alkalosis Endocrine/metabolic 1.1 0.901 – 1.34 0.351 101 1053 exclusion phecode
276.5 Hypovolemia Endocrine/metabolic 1.18 1.13 – 1.23 1.85e-14 2355 26504 exclusion phecode
276.6 Fluid overload Endocrine/metabolic 1.21 1.09 – 1.36 0.000615 338 4228 exclusion phecode
276.8 Polydipsia Endocrine/metabolic 1.2 0.981 – 1.47 0.0755 100 1224 exclusion phecode
277 Other disorders of metabolism Endocrine/metabolic 1.12 1.04 – 1.2 0.00287 800 8467 exclusion phecode
277.4 Disorders of bilirubin excretion Endocrine/metabolic 1.04 0.933 – 1.17 0.458 331 3378 exclusion phecode
277.5 Other disorders of lipoid metabolism Endocrine/metabolic 0.971 0.83 – 1.14 0.716 176 2132 exclusion phecode
277.51 Lipoprotein disorders Endocrine/metabolic 0.683 0.489 – 0.956 0.0262 38 483 exclusion phecode
278 Overweight, obesity and other hyperalimentation Endocrine/metabolic 1.36 1.33 – 1.39 4.78e-163 8569 102682 exclusion phecode
278.1 Obesity Endocrine/metabolic 1.36 1.33 – 1.39 2.79e-164 8433 101134 exclusion phecode
278.3 Localized adiposity Endocrine/metabolic 1.14 0.881 – 1.46 0.328 75 802 exclusion phecode
278.4 Abnormal weight gain Endocrine/metabolic 1.51 1.14 – 1.99 0.00369 52 627 exclusion phecode
279 Disorders involving the immune mechanism Endocrine/metabolic 1.03 0.898 – 1.18 0.676 233 2364 exclusion phecode
279.1 Immunity deficiency Endocrine/metabolic 1.02 0.881 – 1.19 0.755 194 1984 exclusion phecode
279.11 Deficiency of humoral immunity Endocrine/metabolic 1.03 0.858 – 1.24 0.728 131 1313 exclusion phecode
279.7 Other immunological findings Endocrine/metabolic 1.04 0.907 – 1.19 0.583 227 2290 exclusion phecode
280 Iron deficiency anemias Hematopoietic 1.08 1.05 – 1.11 1.92e-09 6465 72172 exclusion phecode
280.1
Iron deficiency anemias, unspecified or not due
Iron deficiency anemias, unspecified or not due to blood loss
 Hematopoietic 1.08 1.05 – 1.11 4.82e-09 6180 69311 exclusion phecode
280.2
Iron deficiency anemia secondary to blood loss
Iron deficiency anemia secondary to blood loss (chronic)
 Hematopoietic 1.11 1 – 1.22 0.0425 422 4338 exclusion phecode
281 Other deficiency anemia Hematopoietic 1.1 1.02 – 1.17 0.00751 932 10541 exclusion phecode
281.1 Megaloblastic anemia Hematopoietic 1.1 1.02 – 1.18 0.00769 893 10104 exclusion phecode
281.11 Pernicious anemia Hematopoietic 1.11 1.02 – 1.2 0.0158 618 7120 exclusion phecode
281.12 Other vitamin B12 deficiency anemia Hematopoietic 1.06 0.9 – 1.26 0.465 149 1678 exclusion phecode
281.13 Folate-deficiency anemia Hematopoietic 1.13 0.965 – 1.33 0.126 161 1725 exclusion phecode
281.9 Deficiency anemias Hematopoietic 0.936 0.688 – 1.27 0.672 46 514 exclusion phecode
282 Hereditary hemolytic anemias Hematopoietic 1.18 0.995 – 1.41 0.0575 133 1422 exclusion phecode
282.8 Other hemoglobinopathies Hematopoietic 1.21 0.925 – 1.59 0.163 51 531 exclusion phecode
282.9 Other hereditary hemolytic anemias Hematopoietic 1 0.79 – 1.27 0.978 72 809 exclusion phecode
283 Acquired hemolytic anemias Hematopoietic 1.01 0.834 – 1.21 0.953 117 1290 exclusion phecode
283.1 Autoimmune hemolytic anemias Hematopoietic 1.03 0.831 – 1.27 0.801 89 996 exclusion phecode
284 Aplastic anemia Hematopoietic 1.09 0.979 – 1.21 0.117 379 4117 exclusion phecode
285 Other anemias Hematopoietic 1.05 1.03 – 1.07 4.99e-07 10456 114585 exclusion phecode
285.1 Acute posthemorrhagic anemia Hematopoietic 1 0.88 – 1.14 0.986 253 2590 exclusion phecode
285.2 Anemia of chronic disease Hematopoietic 0.976 0.896 – 1.06 0.585 573 6568 exclusion phecode
285.22 Anemia in neoplastic disease Hematopoietic 0.957 0.861 – 1.06 0.417 381 3904 exclusion phecode
286 Coagulation defects Hematopoietic 1.1 1.02 – 1.18 0.0126 825 8736 exclusion phecode
286.1 Congenital coagulation defects Hematopoietic 1.1 0.994 – 1.22 0.0641 416 4369 exclusion phecode
286.11 Von willebrand's disease Hematopoietic 1.08 0.877 – 1.34 0.455 91 918 exclusion phecode
286.12
Congenital deficiency of other clotting factors
Congenital deficiency of other clotting factors (including factor VII)
 Hematopoietic 1.11 0.979 – 1.27 0.1 261 2795 exclusion phecode
286.13 Congenital factor VIII disorder Hematopoietic 1.25 0.942 – 1.66 0.122 55 597 exclusion phecode
286.5
Hemorrhagic disorder due to intrinsic
Hemorrhagic disorder due to intrinsic circulating anticoagulants
 Hematopoietic 1.14 0.9 – 1.44 0.282 72 797 exclusion phecode
286.7 Other and unspecified coagulation defects Hematopoietic 1.1 0.985 – 1.23 0.0911 346 3660 exclusion phecode
287 Purpura and other hemorrhagic conditions Hematopoietic 1.08 1.02 – 1.14 0.00639 1469 15512 exclusion phecode
287.1 Spontaneous ecchymoses Hematopoietic 1.07 0.88 – 1.3 0.495 111 1211 exclusion phecode
287.2 Allergic purpura Hematopoietic 1.1 0.805 – 1.51 0.541 45 486 exclusion phecode
287.3 Thrombocytopenia Hematopoietic 1.07 1.02 – 1.14 0.0103 1383 14596 exclusion phecode
287.31 Primary thrombocytopenia Hematopoietic 1.1 0.99 – 1.23 0.0771 374 3961 exclusion phecode
287.32 Secondary thrombocytopenia Hematopoietic 0.971 0.756 – 1.25 0.818 65 710 exclusion phecode
288 Diseases of white blood cells Hematopoietic 1.04 1 – 1.08 0.0343 3503 35525 exclusion phecode
288.1 Decreased white blood cell count Hematopoietic 1.04 1 – 1.08 0.0411 2964 29932 exclusion phecode
288.11 Neutropenia Hematopoietic 1.04 1 – 1.08 0.0471 2971 30014 exclusion phecode
288.3 Eosinophilia Hematopoietic 0.908 0.702 – 1.18 0.466 62 663 exclusion phecode
289 Other diseases of blood and blood-forming organs Hematopoietic 1.08 0.999 – 1.16 0.0526 774 8112 exclusion phecode
289.3
Personal history of diseases of blood and
Personal history of diseases of blood and blood-forming organs
 Hematopoietic 1.06 0.929 – 1.2 0.399 259 2760 exclusion phecode
289.4 Lymphadenitis Hematopoietic 1.04 0.994 – 1.08 0.092 2355 24586 exclusion phecode
289.5 Diseases of spleen Hematopoietic 1.11 1.01 – 1.23 0.0308 434 4831 exclusion phecode
289.8 Polycythemia, secondary Hematopoietic 1.1 0.967 – 1.26 0.146 254 2705 exclusion phecode
289.9 Abnormality of red blood cells Hematopoietic 1.47 1.15 – 1.88 0.00205 76 842 exclusion phecode
290
Delirium dementia and amnestic and other
Delirium dementia and amnestic and other cognitive disorders
 Mental Disorders 1.1 1.04 – 1.16 0.000261 1641 17903 exclusion phecode
290.1 Dementias Mental Disorders 1.08 1.01 – 1.16 0.0249 857 9276 exclusion phecode
290.11 Alzheimer's disease Mental Disorders 1.1 0.99 – 1.22 0.0779 386 3981 exclusion phecode
290.16 Vascular dementia Mental Disorders 1.15 0.973 – 1.36 0.102 152 1848 exclusion phecode
290.2 Delirium due to conditions classified elsewhere Mental Disorders 1.1 1.01 – 1.2 0.0292 539 6035 exclusion phecode
290.3
Other persistent mental disorders due to
Other persistent mental disorders due to conditions classified elsewhere
 Mental Disorders 0.8 0.628 – 1.02 0.072 66 689 exclusion phecode
291
Other specified nonpsychotic and/or transient
Other specified nonpsychotic and/or transient mental disorders
 Mental Disorders 1.16 1.07 – 1.25 0.000136 722 7929 exclusion phecode
291.1
Transient mental disorders due to conditions
Transient mental disorders due to conditions classified elsewhere
 Mental Disorders 1.18 0.98 – 1.42 0.0802 113 1266 exclusion phecode
291.4
Specific nonpsychotic mental disorders due to
Specific nonpsychotic mental disorders due to brain damage
 Mental Disorders 1.04 0.917 – 1.18 0.529 252 2680 exclusion phecode
291.8 Alteration of consciousness Mental Disorders 1.22 1.1 – 1.35 0.000233 373 4141 exclusion phecode
292 Neurological disorders Mental Disorders 1.09 1.06 – 1.13 1.47e-07 3987 43204 exclusion phecode
292.1 Aphasia/speech disturbance Mental Disorders 1.11 1.05 – 1.18 0.000238 1287 14150 exclusion phecode
292.2 Mild cognitive impairment Mental Disorders 1.06 0.904 – 1.25 0.471 159 1770 exclusion phecode
292.3 Memory loss Mental Disorders 1.09 1 – 1.18 0.0412 644 6520 exclusion phecode
292.4 Altered mental status Mental Disorders 1.05 1 – 1.11 0.0308 1820 20305 exclusion phecode
292.6 Hallucinations Mental Disorders 1.21 1.07 – 1.37 0.00246 269 2892 exclusion phecode
293 Symptoms involving head and neck Mental Disorders 1.08 1.03 – 1.13 0.00256 1873 19540 exclusion phecode
293.1
Swelling, mass, or lump in head and neck
Swelling, mass, or lump in head and neck [Space-occupying lesion, intracranial NOS]
 Mental Disorders 1.08 1 – 1.16 0.0361 831 8486 exclusion phecode
295 Schizophrenia and other psychotic disorders Mental Disorders 1.06 0.983 – 1.14 0.131 730 8042 exclusion phecode
295.1 Schizophrenia Mental Disorders 1.01 0.919 – 1.1 0.876 495 5507 exclusion phecode
295.2 Paranoid disorders Mental Disorders 1.12 0.948 – 1.32 0.182 152 1690 exclusion phecode
295.3 Psychosis Mental Disorders 1.14 0.968 – 1.34 0.118 155 1622 exclusion phecode
296 Mood disorders Mental Disorders 1.15 1.12 – 1.17 2.74e-42 11154 118283 exclusion phecode
296.1 Bipolar Mental Disorders 0.996 0.931 – 1.07 0.909 949 10113 exclusion phecode
296.2 Depression Mental Disorders 1.16 1.14 – 1.18 1.72e-47 10575 112246 exclusion phecode
296.22 Major depressive disorder Mental Disorders 1.08 0.963 – 1.22 0.185 317 3450 exclusion phecode
297.2 Suicide or self-inflicted injury Mental Disorders 1.11 0.977 – 1.26 0.111 276 2948 exclusion phecode
300 Anxiety disorders Mental Disorders 1.13 1.1 – 1.16 8.61e-20 6285 65322 exclusion phecode
300.1 Anxiety disorder Mental Disorders 1.13 1.1 – 1.16 2.44e-19 5813 60361 exclusion phecode
300.11 Generalized anxiety disorder Mental Disorders 1.08 0.9 – 1.29 0.415 137 1422 exclusion phecode
300.12 Agorophobia, social phobia, and panic disorder Mental Disorders 1.13 1.04 – 1.23 0.00294 650 6752 exclusion phecode
300.13 Phobia Mental Disorders 1.21 1.1 – 1.33 0.000132 453 4783 exclusion phecode
300.3 Obsessive-compulsive disorders Mental Disorders 1.19 0.992 – 1.43 0.0608 131 1352 exclusion phecode
300.4 Dysthymic disorder Mental Disorders 1.35 1.01 – 1.81 0.0447 47 498 exclusion phecode
300.8 Acute reaction to stress Mental Disorders 1.19 0.981 – 1.45 0.0764 112 1186 exclusion phecode
300.9 Posttraumatic stress disorder Mental Disorders 1.13 0.92 – 1.39 0.246 102 1082 exclusion phecode
301 Personality disorders Mental Disorders 1.24 1.1 – 1.4 0.000463 276 3211 exclusion phecode
301.2 Antisocial/borderline personality disorder Mental Disorders 1.2 0.987 – 1.46 0.0676 100 1151 exclusion phecode
302 Sexual and gender identity disorders Mental Disorders 1.1 0.961 – 1.25 0.17 231 2630 exclusion phecode
303 Psychogenic and somatoform disorders Mental Disorders 0.994 0.901 – 1.1 0.898 437 4460 exclusion phecode
303.3 Psychogenic disorder Mental Disorders 0.938 0.837 – 1.05 0.269 333 3341 exclusion phecode
303.4 Somatoform disorder Mental Disorders 1.23 1.02 – 1.48 0.0328 110 1186 exclusion phecode
304 Adjustment reaction Mental Disorders 1.1 0.971 – 1.24 0.136 263 2829 exclusion phecode
305.2 Eating disorder Mental Disorders 1.08 0.856 – 1.35 0.531 80 868 exclusion phecode
306 Other mental disorder Mental Disorders 1.17 1.15 – 1.18 8.08e-115 24886 217816 exclusion phecode
306.9 Tension headache Mental Disorders 1.19 1.05 – 1.35 0.00551 289 3047 exclusion phecode
313 Pervasive developmental disorders Mental Disorders 0.929 0.718 – 1.2 0.575 63 732 exclusion phecode
313.3 Autism Mental Disorders 0.903 0.663 – 1.23 0.52 42 511 exclusion phecode
315 Develomental delays and disorders Mental Disorders 1.12 0.99 – 1.26 0.0721 302 3293 exclusion phecode
315.1 Learning disorder Mental Disorders 1.17 0.979 – 1.4 0.0836 125 1539 exclusion phecode
315.2 Speech and language disorder Mental Disorders 1.06 0.839 – 1.34 0.62 76 806 exclusion phecode
316 Substance addiction and disorders Mental Disorders 1.14 1.1 – 1.17 5.23e-17 4802 50004 exclusion phecode
316.1 Polyneuropathy due to drugs Mental Disorders 1.37 1.04 – 1.8 0.0234 55 568 exclusion phecode
317 Alcohol-related disorders Mental Disorders 1.12 1.1 – 1.15 2.2e-33 11642 119575 exclusion phecode
317.1 Alcoholism Mental Disorders 1.13 1.1 – 1.15 2.93e-25 8145 83748 exclusion phecode
317.11 Alcoholic liver damage Mental Disorders 1.26 1.17 – 1.37 1.01e-08 674 7891 exclusion phecode
318 Tobacco use disorder Mental Disorders 1.18 1.17 – 1.2 1.98e-100 17504 175090 exclusion phecode
320 Meningitis Neurological 1.16 1.04 – 1.28 0.00508 413 4228 exclusion phecode
323 Encephalitis Neurological 0.98 0.873 – 1.1 0.726 320 3246 exclusion phecode
323.2 Acute (transverse) myelitis Neurological 0.789 0.609 – 1.02 0.0738 69 704 exclusion phecode
324 Other CNS infection and poliomyelitis Neurological 1.18 1.04 – 1.35 0.00885 265 2741 exclusion phecode
327 Sleep disorders Neurological 1.1 1.03 – 1.17 0.00468 991 10938 exclusion phecode
327.3 Sleep apnea Neurological 1.29 1.24 – 1.33 1.12e-47 3577 41582 exclusion phecode
327.4 Insomnia Neurological 0.967 0.813 – 1.15 0.709 147 1575 exclusion phecode
327.41 Organic or persistent insomnia Neurological 1.01 0.838 – 1.21 0.929 125 1325 exclusion phecode
331 Other cerebral degenerations Neurological 1.1 1.03 – 1.17 0.00324 1005 10696 exclusion phecode
331.1 Hydrocephalus Neurological 1.03 0.938 – 1.13 0.539 464 4760 exclusion phecode
331.9 Cerebral degeneration, unspecified Neurological 1.13 1.02 – 1.26 0.0244 356 4011 exclusion phecode
332 Parkinson's disease Neurological 0.996 0.934 – 1.06 0.91 1036 10429 exclusion phecode
333
Extrapyramidal disease and abnormal movement
Extrapyramidal disease and abnormal movement disorders
 Neurological 1.13 1.05 – 1.21 0.00144 802 8440 exclusion phecode
333.1 Essential tremor Neurological 1.09 0.933 – 1.27 0.286 187 2008 exclusion phecode
333.2 Myoclonus Neurological 1.63 1.3 – 2.03 1.92e-05 86 910 exclusion phecode
333.4 Torsion dystonia Neurological 1.08 0.945 – 1.24 0.249 233 2398 exclusion phecode
334 Degenerative disease of the spinal cord Neurological 1.16 1.1 – 1.22 9.8e-09 1634 17019 exclusion phecode
334.1 Spinocerebellar disease Neurological 1.1 0.902 – 1.34 0.346 107 1105 exclusion phecode
334.2 Anterior horn cell disease Neurological 0.996 0.868 – 1.14 0.957 221 2292 exclusion phecode
335 Multiple sclerosis Neurological 1.01 0.952 – 1.07 0.752 1260 12798 exclusion phecode
337 Disorders of the autonomic nervous system Neurological 1.18 1.03 – 1.35 0.0177 228 2499 exclusion phecode
337.1 Peripheral autonomic neuropathy Neurological 1.14 0.864 – 1.49 0.361 59 669 exclusion phecode
338 Pain Neurological 1.18 1.1 – 1.28 1.82e-05 699 7279 exclusion phecode
338.1 Acute pain Neurological 1.22 1.09 – 1.35 0.000395 356 3713 exclusion phecode
338.2 Chronic pain Neurological 1.15 1.03 – 1.29 0.0103 349 3627 exclusion phecode
339 Other headache syndromes Neurological 1.12 1.09 – 1.15 2.75e-20 7225 74386 exclusion phecode
340 Migraine Neurological 1.08 1.03 – 1.12 0.000318 2697 27382 exclusion phecode
340.1 Migrain with aura Neurological 1.04 0.905 – 1.2 0.565 200 2024 exclusion phecode
341
Other demyelinating diseases of central nervous
Other demyelinating diseases of central nervous system
 Neurological 1 0.874 – 1.15 0.995 234 2434 exclusion phecode
342 Hemiplegia Neurological 1.16 1.1 – 1.23 2.64e-07 1275 14011 exclusion phecode
343 Infantile cerebral palsy Neurological 1 0.842 – 1.2 0.963 132 1366 exclusion phecode
344 Other paralytic syndromes Neurological 1.17 1.07 – 1.27 4e-04 590 6208 exclusion phecode
345 Epilepsy, recurrent seizures, convulsions Neurological 1.1 1.06 – 1.13 1.56e-09 4610 47531 exclusion phecode
345.1 Epilepsy Neurological 1.13 1.05 – 1.21 0.00105 791 8226 exclusion phecode
345.11 Generalized convulsive epilepsy Neurological 1.18 1.07 – 1.31 0.0013 395 4182 exclusion phecode
345.12 Partial epilepsy Neurological 1.11 0.976 – 1.26 0.113 259 2640 exclusion phecode
345.3 Convulsions Neurological 1.1 1.05 – 1.15 5.41e-05 2042 21119 exclusion phecode
346.1
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of skull and head
 Neurological 1.22 1.01 – 1.46 0.0347 127 1338 exclusion phecode
348 Other conditions of brain Neurological 1.21 1.12 – 1.3 2.54e-06 678 7378 exclusion phecode
348.2 Cerebral edema and compression of brain Neurological 1.2 1.06 – 1.37 0.00524 238 2553 exclusion phecode
348.4 Cerebral cysts Neurological 1.11 0.92 – 1.33 0.281 120 1284 exclusion phecode
348.7 Coma Neurological 1.15 1.02 – 1.29 0.0186 330 3373 exclusion phecode
348.8 Encephalopathy, not elsewhere classified Neurological 1.18 1.03 – 1.35 0.0171 208 2345 exclusion phecode
348.9 Other conditions of brain, NOS Neurological 1.09 0.973 – 1.21 0.142 346 3702 exclusion phecode
349
Other and unspecified disorders of the nervous
Other and unspecified disorders of the nervous system
 Neurological 1.14 1.01 – 1.28 0.0298 302 3234 exclusion phecode
350 Abnormal movement Neurological 1.14 1.1 – 1.19 5.62e-10 2322 25008 exclusion phecode
350.1 Abnormal involuntary movements Neurological 1.13 1.05 – 1.22 0.000835 799 8332 exclusion phecode
350.2 Abnormality of gait Neurological 1.14 1.08 – 1.2 3.74e-06 1358 14903 exclusion phecode
350.3 Lack of coordination Neurological 1.26 1.13 – 1.42 4.2e-05 316 3416 exclusion phecode
350.6 Disturbances of sensation of smell and taste Neurological 1.2 0.887 – 1.63 0.236 50 508 exclusion phecode
351 Other peripheral nerve disorders Neurological 1.14 1.12 – 1.16 2.58e-40 11191 118192 exclusion phecode
352 Disorders of other cranial nerves Neurological 1.19 1.12 – 1.26 6.99e-09 1234 12993 exclusion phecode
352.1 Trigeminal nerve disorders [CN5] Neurological 1.17 1.06 – 1.29 0.00202 435 4427 exclusion phecode
352.2 Facial nerve disorders [CN7] Neurological 1.19 1.1 – 1.28 4.32e-06 776 8326 exclusion phecode
353 Nerve root and plexus disorders Neurological 1.18 1.11 – 1.26 2.54e-07 1036 10700 exclusion phecode
353.1 Nerve plexus lesions Neurological 1.05 0.863 – 1.28 0.622 109 1084 exclusion phecode
353.2 Nerve root lesions Neurological 1.43 1.07 – 1.91 0.0153 52 533 exclusion phecode
356 Hereditary and idiopathic peripheral neuropathy Neurological 0.931 0.779 – 1.11 0.436 137 1416 exclusion phecode
357 Inflammatory and toxic neuropathy Neurological 1.23 1.15 – 1.31 7.98e-11 1068 12730 exclusion phecode
358 Myoneural disorders Neurological 1.02 0.883 – 1.19 0.752 190 1980 exclusion phecode
358.1 Myasthenia gravis Neurological 1.08 0.921 – 1.26 0.346 172 1804 exclusion phecode
359 Muscular dystrophies and other myopathies Neurological 1.21 1.09 – 1.34 0.000238 400 4400 exclusion phecode
359.1 Muscular dystrophies Neurological 1.09 0.895 – 1.32 0.405 116 1151 exclusion phecode
359.2 Myopathy Neurological 1.28 1.14 – 1.44 3.32e-05 299 3404 exclusion phecode
360 Disorders of the globe Sense Organs 1.01 0.902 – 1.14 0.827 312 3184 exclusion phecode
360.2 Progressive myopia Sense Organs 0.997 0.871 – 1.14 0.96 235 2374 exclusion phecode
361 Retinal detachments and defects Sense Organs 0.983 0.947 – 1.02 0.364 3031 30390 exclusion phecode
361.1 Retinal detachment with retinal defect Sense Organs 0.952 0.9 – 1.01 0.0919 1306 13014 exclusion phecode
361.2 Retinoschisis and retinal cysts Sense Organs 0.831 0.644 – 1.07 0.156 60 639 exclusion phecode
362 Other retinal disorders Sense Organs 1.04 0.999 – 1.07 0.0544 3251 35990 exclusion phecode
362.2
Degeneration of macula and posterior pole of
Degeneration of macula and posterior pole of retina
 Sense Organs 1.03 0.98 – 1.08 0.258 1902 20471 exclusion phecode
362.29 Macular degeneration (senile) of retina NOS Sense Organs 1.03 0.98 – 1.08 0.255 1900 20441 exclusion phecode
362.3 Other nondiabetic retinopathy Sense Organs 1.02 0.854 – 1.22 0.818 127 1516 exclusion phecode
362.31 Separation of retinal layers Sense Organs 1.02 0.83 – 1.26 0.826 92 926 exclusion phecode
362.4 Retinal vascular changes and abnomalities Sense Organs 1.13 1.04 – 1.21 0.00251 700 7915 exclusion phecode
362.6 Peripheral retinal degenerations Sense Organs 0.948 0.809 – 1.11 0.506 166 1712 exclusion phecode
362.7 Hereditary retinal dystrophies Sense Organs 1.07 0.849 – 1.35 0.561 79 773 exclusion phecode
362.8 Retinal hemorrhage/ischemia Sense Organs 1.07 0.877 – 1.3 0.516 102 1090 exclusion phecode
363
Chorioretinal inflammations, scars, and other
Chorioretinal inflammations, scars, and other disorders of choroid
 Sense Organs 0.966 0.821 – 1.14 0.674 150 1614 exclusion phecode
363.3 Chorioretinal scars Sense Organs 0.788 0.601 – 1.03 0.086 53 661 exclusion phecode
364 Corneal opacity and other disorders of cornea Sense Organs 0.992 0.91 – 1.08 0.856 587 6070 exclusion phecode
364.1 Corneal opacity Sense Organs 1.04 0.829 – 1.31 0.725 81 847 exclusion phecode
364.2 Corneal edema Sense Organs 1.16 0.913 – 1.47 0.227 71 741 exclusion phecode
364.4 Corneal degenerations Sense Organs 0.968 0.826 – 1.13 0.687 173 1891 exclusion phecode
364.41 Keratoconus Sense Organs 0.865 0.682 – 1.1 0.233 81 824 exclusion phecode
364.5 Corneal dystrophy Sense Organs 0.878 0.757 – 1.02 0.0878 198 1990 exclusion phecode
364.9 Cornea replaced by transplant Sense Organs 0.927 0.749 – 1.15 0.486 93 939 exclusion phecode
365 Glaucoma Sense Organs 1.07 1.04 – 1.11 2.24e-05 3986 41133 exclusion phecode
365.1 Open-angle glaucoma Sense Organs 1.04 0.97 – 1.11 0.279 938 9624 exclusion phecode
365.11 Primary open angle glaucoma Sense Organs 1.04 0.972 – 1.11 0.258 932 9574 exclusion phecode
365.2 Primary angle-closure glaucoma Sense Organs 1.02 0.938 – 1.1 0.685 649 6579 exclusion phecode
366 Cataract Sense Organs 1.06 1.04 – 1.07 7.69e-12 17642 158330 exclusion phecode
366.1 Nonsenile Cataract Sense Organs 1.19 0.934 – 1.52 0.159 65 669 exclusion phecode
366.2 Senile cataract Sense Organs 1.07 1.05 – 1.1 2.04e-08 7293 76693 exclusion phecode
366.3 Traumatic cataract Sense Organs 0.93 0.755 – 1.15 0.497 94 928 exclusion phecode
367
Disorders of refraction and accommodation
Disorders of refraction and accommodation; blindness and low vision
 Sense Organs 1.05 1.01 – 1.1 0.0237 2194 22670 exclusion phecode
367.1 Myopia Sense Organs 1.02 0.958 – 1.08 0.573 1159 11766 exclusion phecode
367.2 Astigmatism Sense Organs 1.1 0.943 – 1.29 0.222 178 1793 exclusion phecode
367.8 Hypermetropia Sense Organs 1.1 0.962 – 1.26 0.166 241 2395 exclusion phecode
367.9 Blindness and low vision Sense Organs 1.12 1.03 – 1.21 0.00844 616 6764 exclusion phecode
368 Visual disturbances Sense Organs 1.07 1.03 – 1.11 0.00089 2668 27947 exclusion phecode
368.1 Amblyopia Sense Organs 0.994 0.903 – 1.09 0.907 465 4962 exclusion phecode
368.2 Diplopia and disorders of binocular vision Sense Organs 1.13 1.05 – 1.23 0.00227 658 6893 exclusion phecode
368.3 Anisometropia Sense Organs 1.07 0.896 – 1.27 0.471 145 1440 exclusion phecode
368.4 Visual field defects Sense Organs 1.1 0.974 – 1.24 0.126 288 3118 exclusion phecode
368.9 Subjective visual disturbances Sense Organs 1.13 1.04 – 1.23 0.00538 559 5794 exclusion phecode
369 Infection of the eye Sense Organs 1.05 0.959 – 1.15 0.299 508 5221 exclusion phecode
369.2 Eye infection, viral Sense Organs 0.989 0.824 – 1.19 0.902 117 1175 exclusion phecode
369.5 Conjunctivitis, infectious Sense Organs 1.09 0.944 – 1.25 0.246 194 2013 exclusion phecode
370 Keratitis Sense Organs 1.01 0.89 – 1.15 0.845 255 2702 exclusion phecode
370.1 Corneal ulcer Sense Organs 0.968 0.806 – 1.16 0.725 127 1334 exclusion phecode
371 Inflammation of the eye Sense Organs 1.01 0.968 – 1.05 0.76 2863 28793 exclusion phecode
371.1 Uveitis, noninfectious or NOS Sense Organs 1 0.909 – 1.1 0.963 436 4569 exclusion phecode
371.3 Inflammation of eyelids Sense Organs 0.992 0.95 – 1.04 0.727 2236 22240 exclusion phecode
372 Disorders of conjunctiva Sense Organs 1.07 0.995 – 1.16 0.068 707 7142 exclusion phecode
374 Other disorders of eyelids Sense Organs 1.08 1.05 – 1.11 1.4e-07 5212 53459 exclusion phecode
374.1 Ectropion or entropion Sense Organs 1.1 1.03 – 1.17 0.00673 951 9879 exclusion phecode
374.3 Ptosis of eyelid Sense Organs 1.08 1.02 – 1.13 0.00463 1675 17171 exclusion phecode
375 Disorders of lacrimal system Sense Organs 1.05 1.01 – 1.1 0.0241 2031 20754 exclusion phecode
375.2 Epiphora Sense Organs 1.07 0.995 – 1.15 0.0689 826 8400 exclusion phecode
376 Disorders of the orbit Sense Organs 0.857 0.681 – 1.08 0.189 78 807 exclusion phecode
377 Disorders of optic nerve and visual pathways Sense Organs 1.08 0.964 – 1.21 0.184 327 3423 exclusion phecode
377.1 Optic atrophy Sense Organs 1 0.741 – 1.36 0.985 50 535 exclusion phecode
377.3 Optic neuritis/neuropathy Sense Organs 1.11 0.908 – 1.35 0.314 115 1197 exclusion phecode
378
Strabismus and other disorders of binocular eye
Strabismus and other disorders of binocular eye movements
 Sense Organs 1.04 0.981 – 1.1 0.197 1294 13387 exclusion phecode
378.1 Strabismus (not specified as paralytic) Sense Organs 1.04 0.968 – 1.11 0.298 854 8629 exclusion phecode
378.2 Nystagmus and other irregular eye movements Sense Organs 1.02 0.879 – 1.18 0.811 188 2006 exclusion phecode
378.5 Paralytic strabismus Sense Organs 1.04 0.919 – 1.19 0.504 243 2625 exclusion phecode
379 Other disorders of eye Sense Organs 1.05 1.01 – 1.09 0.00915 3229 34624 exclusion phecode
379.2 Disorders of vitreous body Sense Organs 1.04 0.975 – 1.1 0.257 1155 12781 exclusion phecode
379.3 Aphakia and other disorders of lens Sense Organs 1.08 1.02 – 1.13 0.0046 1597 16868 exclusion phecode
379.4 Anomalies of pupillary function Sense Organs 1.2 0.934 – 1.55 0.152 69 668 exclusion phecode
379.5 Disorders of iris and ciliary body Sense Organs 1.02 0.92 – 1.14 0.664 357 3776 exclusion phecode
379.9 Pain, swelling or discharge of eye Sense Organs 1.07 0.91 – 1.27 0.395 150 1609 exclusion phecode
380 Disorders of external ear Sense Organs 1.05 0.964 – 1.14 0.264 581 6004 exclusion phecode
380.1 Otitis externa Sense Organs 1.1 0.999 – 1.21 0.0522 439 4850 exclusion phecode
380.4 Impacted cerumen Sense Organs 0.984 0.879 – 1.1 0.778 332 3387 exclusion phecode
381 Otitis media and Eustachian tube disorders Sense Organs 1.09 1.04 – 1.14 0.000239 1970 20237 exclusion phecode
381.1 Otitis media Sense Organs 1.11 1.06 – 1.17 3.76e-05 1609 16620 exclusion phecode
381.11 Suppurative and unspecified otitis media Sense Organs 1.09 1.02 – 1.18 0.0179 781 8014 exclusion phecode
381.2 Eustachian tube disorders Sense Organs 1.05 0.899 – 1.22 0.559 185 1831 exclusion phecode
381.3 Mastoiditis & related conditions Sense Organs 1.11 0.937 – 1.31 0.235 152 1613 exclusion phecode
381.9 Otorrhea Sense Organs 0.965 0.847 – 1.1 0.596 254 2647 exclusion phecode
382 Otalgia Sense Organs 1.06 0.943 – 1.2 0.313 286 2916 exclusion phecode
383 Otosclerosis Sense Organs 0.954 0.846 – 1.07 0.438 299 2952 exclusion phecode
384 Other disorders of tympanic membrane Sense Organs 1.12 1.06 – 1.19 0.000101 1212 12284 exclusion phecode
384.4 Perforation of tympanic membrane Sense Organs 1.15 1.08 – 1.23 2.14e-05 975 9877 exclusion phecode
385 Other disorders of middle ear and mastoid Sense Organs 1.1 1.02 – 1.18 0.0177 727 7369 exclusion phecode
385.3 Cholesteatoma Sense Organs 1.06 0.97 – 1.15 0.208 562 5687 exclusion phecode
385.5
Tympanosclerosis and middle ear disease related
Tympanosclerosis and middle ear disease related to otitis media
 Sense Organs 1.12 0.977 – 1.29 0.101 225 2279 exclusion phecode
386
Vertiginous syndromes and other disorders of
Vertiginous syndromes and other disorders of vestibular system
 Sense Organs 1.09 1.04 – 1.15 0.000555 1614 16424 exclusion phecode
386.1 Meniere's disease Sense Organs 1.06 0.966 – 1.15 0.231 544 5454 exclusion phecode
386.2 Peripheral or central vertigo Sense Organs 1.08 0.973 – 1.21 0.144 344 3533 exclusion phecode
386.3 Labyrinthitis Sense Organs 1.12 1.04 – 1.21 0.00304 708 7253 exclusion phecode
386.9
Dizziness and giddiness (Light-headedness and
Dizziness and giddiness (Light-headedness and vertigo)
 Sense Organs 1.13 1.1 – 1.17 9.55e-15 4162 43123 exclusion phecode
388 Other disorders of ear Sense Organs 1.03 0.883 – 1.2 0.703 186 1909 exclusion phecode
389 Hearing loss Sense Organs 1.1 1.06 – 1.14 3.77e-08 3771 39261 exclusion phecode
389.1 Sensorineural hearing loss Sense Organs 1.09 0.986 – 1.21 0.0931 408 4262 exclusion phecode
389.2 Conductive hearing loss Sense Organs 1.06 0.96 – 1.17 0.248 416 4232 exclusion phecode
389.4 Tinnitus Sense Organs 1.1 1 – 1.21 0.0505 479 4815 exclusion phecode
394 Rheumatic disease of the heart valves Circulatory System 1.09 1.06 – 1.12 4.91e-08 4358 45542 exclusion phecode
394.2 Mitral valve disease Circulatory System 1.08 1.03 – 1.12 0.000282 2682 27877 exclusion phecode
394.3 Aortic valve disease Circulatory System 1.14 1.07 – 1.21 3.55e-05 1134 11851 exclusion phecode
394.7 Disease of tricuspid valve Circulatory System 1.1 1.03 – 1.18 0.00429 929 9798 exclusion phecode
395 Heart valve disorders Circulatory System 1.09 1.06 – 1.13 2.37e-07 3742 39314 exclusion phecode
395.1 Nonrheumatic mitral valve disorders Circulatory System 1.08 1.04 – 1.13 7.9e-05 2588 26939 exclusion phecode
395.2 Nonrheumatic aortic valve disorders Circulatory System 1.04 0.907 – 1.19 0.576 229 2553 exclusion phecode
395.3 Nonrheumatic tricuspid valve disorders Circulatory System 0.911 0.731 – 1.13 0.403 89 963 exclusion phecode
395.4 Nonrheumatic pulmonary valve disorders Circulatory System 1.07 0.857 – 1.32 0.569 85 899 exclusion phecode
395.6 Heart valve replaced Circulatory System 1.12 1.06 – 1.19 5.36e-05 1308 13910 exclusion phecode
396 Abnormal heart sounds Circulatory System 1.17 1.1 – 1.25 3.07e-06 955 9935 exclusion phecode
401 Hypertension Circulatory System 1.23 1.21 – 1.24 1.27e-421 63455 258352 exclusion phecode
401.1 Essential hypertension Circulatory System 1.23 1.21 – 1.24 1.25e-421 63258 258135 exclusion phecode
401.2 Hypertensive heart and/or renal disease Circulatory System 1.27 1.2 – 1.34 4.2e-17 1356 18130 exclusion phecode
401.21 Hypertensive heart disease Circulatory System 1.38 1.22 – 1.56 2.15e-07 287 3498 exclusion phecode
401.22 Hypertensive chronic kidney disease Circulatory System 1.24 1.17 – 1.32 8.98e-12 1072 14761 exclusion phecode
401.3 Other hypertensive complications Circulatory System 1.11 0.927 – 1.34 0.25 121 1384 exclusion phecode
402
Elevated blood pressure reading without
Elevated blood pressure reading without diagnosis of hypertension
 Circulatory System 1.19 1.12 – 1.25 2.87e-09 1324 14232 exclusion phecode
411 Ischemic Heart Disease Circulatory System 1.19 1.17 – 1.2 2.15e-149 26474 199521 exclusion phecode
411.1 Unstable angina (intermediate coronary syndrome) Circulatory System 1.23 1.2 – 1.27 3.03e-39 4203 48355 exclusion phecode
411.2 Myocardial infarction Circulatory System 1.22 1.2 – 1.25 4.51e-84 10031 105611 exclusion phecode
411.3 Angina pectoris Circulatory System 1.22 1.2 – 1.24 3.64e-102 13082 135305 exclusion phecode
411.4 Coronary atherosclerosis Circulatory System 1.19 1.17 – 1.21 6.49e-103 17076 145560 exclusion phecode
411.41 Aneurysm and dissection of heart Circulatory System 1.08 0.998 – 1.17 0.0557 654 6607 exclusion phecode
411.8
Other chronic ischemic heart disease
Other chronic ischemic heart disease, unspecified
 Circulatory System 1.24 1.22 – 1.27 1.32e-117 12341 123757 exclusion phecode
411.9
Other acute and subacute forms of ischemic
Other acute and subacute forms of ischemic heart disease
 Circulatory System 1.24 1.17 – 1.32 1.75e-11 1039 11418 exclusion phecode
414 Other forms of chronic heart disease Circulatory System 1.18 1.12 – 1.25 4.05e-10 1503 17064 exclusion phecode
414.2 ASCVD Circulatory System 1.09 0.84 – 1.42 0.507 56 673 exclusion phecode
415 Pulmonary heart disease Circulatory System 1.08 1.05 – 1.12 7.74e-07 4049 41907 exclusion phecode
415.11 Pulmonary embolism and infarction, acute Circulatory System 1.03 0.822 – 1.3 0.776 70 698 exclusion phecode
415.2 Chronic pulmonary heart disease Circulatory System 1.05 0.958 – 1.15 0.299 502 5580 exclusion phecode
415.21 Primary pulmonary hypertension Circulatory System 1.02 0.92 – 1.14 0.674 372 4175 exclusion phecode
416 Cardiomegaly Circulatory System 1.2 1.15 – 1.25 1.68e-16 2238 24840 exclusion phecode
418 Nonspecific chest pain Circulatory System 1.14 1.13 – 1.16 2.72e-89 25725 255784 exclusion phecode
418.1 Precordial pain Circulatory System 1.18 1.14 – 1.22 1.13e-18 3162 33658 exclusion phecode
420 Carditis Circulatory System 1.07 1.02 – 1.12 0.00926 1865 19658 exclusion phecode
420.1 Myocarditis Circulatory System 1.01 0.835 – 1.23 0.888 121 1184 exclusion phecode
420.2 Pericarditis Circulatory System 1.06 1 – 1.13 0.04 1199 12513 exclusion phecode
420.21 Acute pericarditis Circulatory System 1.11 0.961 – 1.28 0.155 200 2095 exclusion phecode
420.22 Chronic pericarditis Circulatory System 1.1 0.892 – 1.35 0.379 102 1038 exclusion phecode
420.3 Endocarditis Circulatory System 1.1 1.01 – 1.19 0.0237 621 6684 exclusion phecode
425 Cardiomyopathy Circulatory System 1.16 1.09 – 1.23 1.91e-06 1106 11797 exclusion phecode
425.1 Primary/intrinsic cardiomyopathies Circulatory System 1.16 1.09 – 1.24 1.47e-06 1076 11476 exclusion phecode
425.11 Hypertrophic obstructive cardiomyopathy Circulatory System 1.21 1 – 1.45 0.0468 123 1239 exclusion phecode
425.12 Other hypertrophic cardiomyopathy Circulatory System 1.1 0.931 – 1.29 0.27 153 1515 exclusion phecode
425.8 Other cardiomyopathy Circulatory System 1.22 0.926 – 1.61 0.158 53 557 exclusion phecode
426 Cardiac conduction disorders Circulatory System 1.15 1.12 – 1.18 7.75e-25 5951 64423 exclusion phecode
426.2 Atrioventricular [AV] block Circulatory System 1.15 1.1 – 1.21 3.39e-09 1783 19598 exclusion phecode
426.21 First degree AV block Circulatory System 1.19 1.11 – 1.28 8.21e-07 824 9130 exclusion phecode
426.23 Second degree AV block Circulatory System 1.06 0.956 – 1.17 0.274 387 4169 exclusion phecode
426.24 Atrioventricular block, complete Circulatory System 1.17 1.07 – 1.29 0.00054 491 5429 exclusion phecode
426.25 Other heart block Circulatory System 1.09 0.912 – 1.29 0.355 121 1215 exclusion phecode
426.3 Bundle branch block Circulatory System 1.18 1.14 – 1.23 7.01e-18 2874 31064 exclusion phecode
426.31 Right bundle branch block Circulatory System 1.12 1.06 – 1.19 5.76e-05 1303 13843 exclusion phecode
426.32 Left bundle branch block Circulatory System 1.23 1.16 – 1.29 3.83e-14 1487 16322 exclusion phecode
426.4 Anomalous atrioventricular excitation Circulatory System 1.11 0.962 – 1.27 0.159 224 2201 exclusion phecode
426.8 Other cardiac conduction disorders Circulatory System 1.2 0.921 – 1.57 0.177 55 564 exclusion phecode
426.9 Cardiac pacemaker/device in situ Circulatory System 1.17 1.12 – 1.22 5.1e-12 2065 23036 exclusion phecode
426.91 Cardiac pacemaker in situ Circulatory System 1.16 1.11 – 1.22 3.67e-10 1901 21148 exclusion phecode
427 Cardiac dysrhythmias Circulatory System 1.09 1.07 – 1.11 5e-33 21632 193998 exclusion phecode
427.1 Paroxysmal tachycardia, unspecified Circulatory System 1.08 1.04 – 1.12 5.04e-05 2884 30138 exclusion phecode
427.11 Paroxysmal supraventricular tachycardia Circulatory System 1.06 1.02 – 1.11 0.00811 2122 22187 exclusion phecode
427.12 Paroxysmal ventricular tachycardia Circulatory System 1.15 1.07 – 1.24 8.51e-05 828 8689 exclusion phecode
427.2 Atrial fibrillation and flutter Circulatory System 1.09 1.07 – 1.11 2.26e-21 12898 124582 exclusion phecode
427.3 Other specified cardiac dysrhythmias Circulatory System 1.14 1.09 – 1.18 5.38e-11 2910 30189 exclusion phecode
427.4 Cardiac arrest and ventricular fibrillation Circulatory System 1.16 1.09 – 1.23 8.7e-06 1038 11070 exclusion phecode
427.41 Ventricular fibrillation and flutter Circulatory System 1.12 0.999 – 1.26 0.0529 306 3215 exclusion phecode
427.42 Cardiac arrest Circulatory System 1.19 1.11 – 1.27 1.86e-06 859 9182 exclusion phecode
427.5 Arrhythmia (cardiac) NOS Circulatory System 1.03 0.962 – 1.11 0.388 847 8931 exclusion phecode
427.6 Premature beats Circulatory System 1.06 0.97 – 1.17 0.188 495 5046 exclusion phecode
427.61 Supraventricular premature beats Circulatory System 1.04 0.856 – 1.26 0.704 110 1092 exclusion phecode
427.7 Tachycardia NOS Circulatory System 1.13 1.08 – 1.18 3.72e-07 1922 20648 exclusion phecode
427.8 Sinoatrial node dysfunction (Bradycardia) Circulatory System 1.11 0.995 – 1.23 0.0624 372 3768 exclusion phecode
427.9 Palpitations Circulatory System 1.1 1.07 – 1.14 2.32e-08 3540 36229 exclusion phecode
428 Congestive heart failure; nonhypertensive Circulatory System 1.24 1.2 – 1.28 7.5e-44 4440 51854 exclusion phecode
428.1 Congestive heart failure (CHF) NOS Circulatory System 1.29 1.22 – 1.36 4.13e-22 1530 19540 exclusion phecode
428.2 Heart failure NOS Circulatory System 1.23 1.19 – 1.27 1.02e-32 3573 41209 exclusion phecode
429
Ill-defined descriptions and complications of
Ill-defined descriptions and complications of heart disease
 Circulatory System 1.06 0.975 – 1.15 0.175 644 6769 exclusion phecode
429.1 Heart transplant/surgery Circulatory System 1.11 0.835 – 1.47 0.474 50 593 exclusion phecode
429.2 Abnormal function study of cardiovascular system Circulatory System 1.03 0.935 – 1.13 0.556 467 4932 exclusion phecode
429.3 Symptoms involving cardiovascular system Circulatory System 1.13 0.963 – 1.32 0.138 178 1875 exclusion phecode
430 Intracranial hemorrhage Circulatory System 1.06 1.01 – 1.11 0.0268 1728 17643 exclusion phecode
430.1 Subarachnoid hemorrhage Circulatory System 1.05 0.975 – 1.13 0.206 792 7897 exclusion phecode
430.2 Intracerebral hemorrhage Circulatory System 1.03 0.956 – 1.12 0.406 682 7126 exclusion phecode
430.3 Subdural hemorrhage Circulatory System 1.1 0.968 – 1.26 0.142 245 2472 exclusion phecode
433 Cerebrovascular disease Circulatory System 1.14 1.11 – 1.16 8.69e-27 7542 81511 exclusion phecode
433.1 Occlusion and stenosis of precerebral arteries Circulatory System 1.24 1.16 – 1.32 5.44e-11 1002 10895 exclusion phecode
433.12 Cerebral atherosclerosis Circulatory System 1.18 1.02 – 1.36 0.0277 198 2083 exclusion phecode
433.2 Occlusion of cerebral arteries Circulatory System 1.13 1.09 – 1.17 3.98e-12 3595 39337 exclusion phecode
433.21
Cerebral artery occlusion, with cerebral
Cerebral artery occlusion, with cerebral infarction
 Circulatory System 1.19 1.12 – 1.25 9.92e-10 1398 15620 exclusion phecode
433.3 Cerebral ischemia Circulatory System 1.11 1.06 – 1.15 8.86e-07 2491 26988 exclusion phecode
433.31 Transient cerebral ischemia Circulatory System 1.1 1.05 – 1.15 7.02e-05 1841 19872 exclusion phecode
433.5 Cerebral aneurysm Circulatory System 1.08 0.968 – 1.2 0.176 375 3726 exclusion phecode
433.8 Late effects of cerebrovascular disease Circulatory System 1.19 1.12 – 1.27 7.24e-08 1067 11931 exclusion phecode
440 Atherosclerosis Circulatory System 1.28 1.21 – 1.36 3.66e-15 1071 12769 exclusion phecode
440.1 Atherosclerosis of renal artery Circulatory System 1.2 0.974 – 1.48 0.0867 93 1050 exclusion phecode
440.2 Atherosclerosis of the extremities Circulatory System 1.26 1.16 – 1.37 6.67e-08 585 7417 exclusion phecode
440.9 Atherosclerosis of aorta Circulatory System 1.3 1.13 – 1.48 0.000129 240 2683 exclusion phecode
441 Vascular insufficiency of intestine Circulatory System 1.14 1.04 – 1.24 0.00349 547 5781 exclusion phecode
441.1 Acute vascular insufficiency of intestine Circulatory System 1.08 0.953 – 1.22 0.228 251 2662 exclusion phecode
442 Other aneurysm Circulatory System 1.15 1.09 – 1.21 3.04e-08 1708 17490 exclusion phecode
442.1 Aortic aneurysm Circulatory System 1.13 1.07 – 1.2 1.95e-05 1319 13408 exclusion phecode
442.11 Abdominal aortic aneurysm Circulatory System 1.17 1.09 – 1.26 1.45e-05 820 8506 exclusion phecode
442.2 Aneurysm of iliac artery Circulatory System 1.39 1.13 – 1.7 0.00195 94 917 exclusion phecode
442.3 Aneurysm of artery of lower extremity Circulatory System 1.2 1.01 – 1.41 0.0354 146 1570 exclusion phecode
442.4 Arterial dissection Circulatory System 1.22 0.918 – 1.63 0.17 51 514 exclusion phecode
442.8 Aneurysm of other specified artery Circulatory System 1.17 1 – 1.36 0.0476 185 1913 exclusion phecode
443 Peripheral vascular disease Circulatory System 1.2 1.16 – 1.25 7.44e-23 3006 36571 exclusion phecode
443.1 Raynaud's syndrome Circulatory System 1.06 1 – 1.13 0.0491 1086 10870 exclusion phecode
443.7
Peripheral angiopathy in diseases classified
Peripheral angiopathy in diseases classified elsewhere
 Circulatory System 2.59 1.93 – 3.46 1.66e-10 41 3589 exclusion phecode
443.8 Other specified peripheral vascular diseases Circulatory System 1.2 1.15 – 1.24 4.53e-21 2974 34365 exclusion phecode
443.9 Peripheral vascular disease, unspecified Circulatory System 1.29 1.23 – 1.35 1.02e-26 1922 23831 exclusion phecode
444 Arterial embolism and thrombosis Circulatory System 1.3 1.21 – 1.4 5.01e-12 718 8610 exclusion phecode
444.1
Arterial embolism and thrombosis of lower
Arterial embolism and thrombosis of lower extremity artery
 Circulatory System 1.35 1.23 – 1.49 1.75e-09 406 5146 exclusion phecode
446 Polyarteritis nodosa and allied conditions Circulatory System 1.11 1.03 – 1.19 0.00918 741 7678 exclusion phecode
446.4 Wegener's granulomatosis Circulatory System 1.06 0.909 – 1.24 0.45 172 1723 exclusion phecode
446.5 Giant cell arteritis Circulatory System 1.11 0.995 – 1.24 0.0609 357 3634 exclusion phecode
446.9 Arteritis NOS Circulatory System 1.12 0.971 – 1.29 0.121 210 2248 exclusion phecode
447 Other disorders of arteries and arterioles Circulatory System 1.23 1.16 – 1.31 5.04e-11 1057 12339 exclusion phecode
447.1 Stricture of artery Circulatory System 1.29 1.19 – 1.39 2.28e-10 662 8034 exclusion phecode
448 Disease of capillaries Circulatory System 0.946 0.789 – 1.13 0.551 126 1350 exclusion phecode
450 Noninfectious disorders of lymphatic channels Circulatory System 1.05 0.968 – 1.14 0.233 622 6653 exclusion phecode
451 Phlebitis and thrombophlebitis Circulatory System 1.13 1.09 – 1.16 1.42e-11 3583 37235 exclusion phecode
451.2
Phlebitis and thrombophlebitis of lower
Phlebitis and thrombophlebitis of lower extremities
 Circulatory System 1.13 1.09 – 1.17 7.82e-11 3333 34673 exclusion phecode
452 Other venous embolism and thrombosis Circulatory System 1.11 1.01 – 1.21 0.0245 504 5325 exclusion phecode
454 Varicose veins Circulatory System 1.03 1.01 – 1.05 0.00704 10645 106214 exclusion phecode
454.1 Varicose veins of lower extremity Circulatory System 1.02 1 – 1.04 0.0558 10991 109279 exclusion phecode
454.11 Varicose veins of lower extremity, symptomtic Circulatory System 0.997 0.914 – 1.09 0.947 559 5934 exclusion phecode
455 Hemorrhoids Circulatory System 1.05 1.03 – 1.06 3.44e-10 21963 221341 exclusion phecode
456 Chronic venous insufficiency [CVI] Circulatory System 0.916 0.778 – 1.08 0.296 157 1731 exclusion phecode
457
Encounter for long-term (current) use of
Encounter for long-term (current) use of anticoagulants, antithrombotics, aspirin
 Circulatory System 0.938 0.76 – 1.16 0.554 93 886 exclusion phecode
458 Hypotension Circulatory System 1.08 1.04 – 1.11 8e-07 5060 54226 exclusion phecode
458.1 Orthostatic hypotension Circulatory System 1.15 1.08 – 1.23 4.79e-06 1127 12541 exclusion phecode
458.2 Iatrogenic hypotension Circulatory System 1.18 1.02 – 1.35 0.025 203 2184 exclusion phecode
458.9 Hypotension NOS Circulatory System 1.07 1.03 – 1.11 0.000353 3061 32860 exclusion phecode
459 Other disorders of circulatory system Circulatory System 1.14 1.12 – 1.16 9.61e-51 14299 150891 exclusion phecode
459.1 Hemorrhage NOS Circulatory System 1.11 0.937 – 1.32 0.222 127 1317 exclusion phecode
459.9 Circulatory disease NEC Circulatory System 1.14 1.12 – 1.16 2.91e-51 14148 149588 exclusion phecode
464 Acute sinusitis Respiratory 1.1 0.94 – 1.28 0.243 179 1865 exclusion phecode
465
Acute upper respiratory infections of multiple
Acute upper respiratory infections of multiple or unspecified sites
 Respiratory 1.1 1.05 – 1.15 6.47e-05 2081 21652 exclusion phecode
465.2 Acute pharyngitis Respiratory 1.12 1.03 – 1.2 0.00457 767 7913 exclusion phecode
465.4 Acute laryngitis and tracheitis Respiratory 1.2 1.02 – 1.41 0.0316 155 1573 exclusion phecode
470 Septal Deviations/Turbinate Hypertrophy Respiratory 1.08 1.05 – 1.11 1.75e-06 4369 44045 exclusion phecode
471 Nasal polyps Respiratory 1.1 1.06 – 1.14 1.21e-06 3095 30910 exclusion phecode
472 Chronic pharyngitis and nasopharyngitis Respiratory 1.07 0.997 – 1.15 0.0601 904 9064 exclusion phecode
473 Diseases of the larynx and vocal cords Respiratory 1.08 1.03 – 1.13 0.000556 2338 23998 exclusion phecode
473.1 Chronic laryngitis Respiratory 1.08 0.882 – 1.33 0.447 92 976 exclusion phecode
473.3 Paralysis/spasm of vocal cords or larynx Respiratory 1.08 0.947 – 1.23 0.254 239 2490 exclusion phecode
473.4 Voice disturbance Respiratory 1.05 0.981 – 1.12 0.165 975 10113 exclusion phecode
474 Acute and chronic tonsillitis Respiratory 1.09 1.04 – 1.15 0.000785 1679 16979 exclusion phecode
474.1 Acute tonsillitis Respiratory 1.13 1.03 – 1.23 0.00885 513 5287 exclusion phecode
474.2 Chronic tonsillitis and adenoiditis Respiratory 1.08 1.01 – 1.15 0.021 1070 10754 exclusion phecode
475 Chronic sinusitis Respiratory 1.09 1.05 – 1.14 2.44e-05 2423 24482 exclusion phecode
476 Allergic rhinitis Respiratory 1.01 0.948 – 1.08 0.71 994 10060 exclusion phecode
477 Epistaxis or throat hemorrhage Respiratory 1.13 1.08 – 1.18 1.23e-07 2190 22832 exclusion phecode
478 Throat pain Respiratory 0.973 0.871 – 1.09 0.621 351 3573 exclusion phecode
479 Other upper respiratory disease Respiratory 1.08 1.05 – 1.12 3.97e-06 3780 38512 exclusion phecode
480 Pneumonia Respiratory 1.12 1.1 – 1.14 4.88e-25 9060 96649 exclusion phecode
480.1 Bacterial pneumonia Respiratory 1.12 1.09 – 1.15 3.79e-16 5822 62035 exclusion phecode
480.11 Pneumococcal pneumonia Respiratory 1.12 1.09 – 1.15 2.17e-14 5175 54956 exclusion phecode
480.12 Pseudomonal pneumonia Respiratory 1.62 1.31 – 1.99 5.77e-06 84 854 exclusion phecode
480.2 Viral pneumonia Respiratory 1.14 0.888 – 1.45 0.31 67 677 exclusion phecode
480.3 Pneumonia due to fungus (mycoses) Respiratory 1.34 1.08 – 1.67 0.00723 91 921 exclusion phecode
480.5 Bronchopneumonia and lung abscess Respiratory 1.08 1 – 1.17 0.0464 686 7400 exclusion phecode
481 Influenza Respiratory 1.04 0.921 – 1.16 0.557 310 3102 exclusion phecode
483 Acute bronchitis and bronchiolitis Respiratory 1.15 0.985 – 1.35 0.0763 170 1806 exclusion phecode
495 Asthma Respiratory 1.14 1.13 – 1.16 1.91e-85 23495 237944 exclusion phecode
495.2 Asthma with exacerbation Respiratory 1.2 1.05 – 1.38 0.00854 218 2384 exclusion phecode
496 Chronic airway obstruction Respiratory 1.22 1.19 – 1.24 1.53e-71 9132 94825 exclusion phecode
496.1 Emphysema Respiratory 1.23 1.17 – 1.3 3.31e-15 1565 16169 exclusion phecode
496.2 Chronic bronchitis Respiratory 1.26 1.21 – 1.32 2.3e-29 2544 27371 exclusion phecode
496.21 Obstructive chronic bronchitis Respiratory 1.26 1.21 – 1.32 1.16e-26 2340 25095 exclusion phecode
496.3 Bronchiectasis Respiratory 1.11 1.06 – 1.17 1.4e-05 1737 17711 exclusion phecode
497 Bronchitis Respiratory 1.16 1.07 – 1.27 0.000615 566 5926 exclusion phecode
500 Lung disease due to external agents Respiratory 1.06 0.951 – 1.18 0.287 360 3774 exclusion phecode
500.1 Extrinsic allergic alveolitis Respiratory 0.899 0.711 – 1.14 0.372 72 730 exclusion phecode
500.2 Pneumoconiosis Respiratory 1.15 0.997 – 1.32 0.0553 210 2186 exclusion phecode
501 Pneumonitis due to inhalation of food or vomitus Respiratory 1.11 1.02 – 1.21 0.0131 570 6095 exclusion phecode
502 Postinflammatory pulmonary fibrosis Respiratory 1.14 1.06 – 1.22 0.000439 803 8485 exclusion phecode
503 Pulmonary congestion and hypostasis Respiratory 1.27 1.14 – 1.41 1.16e-05 387 4746 exclusion phecode
504 Other alveolar and parietoalveolar pneumonopathy Respiratory 1.18 1.05 – 1.34 0.00686 287 3065 exclusion phecode
505 Other pulmonary inflamation or edema Respiratory 1.11 0.843 – 1.45 0.466 57 567 exclusion phecode
506 Empyema and pneumothorax Respiratory 1.07 1 – 1.14 0.0492 1040 10616 exclusion phecode
507 Pleurisy; pleural effusion Respiratory 1.1 1.07 – 1.13 3.4e-11 5653 60009 exclusion phecode
508
Pulmonary collapse; interstitial and
Pulmonary collapse; interstitial and compensatory emphysema
 Respiratory 1.14 1.08 – 1.19 2.25e-07 1778 18719 exclusion phecode
509 Respiratory failure, insufficiency, arrest Respiratory 1.21 1.16 – 1.26 2.21e-17 2189 24263 exclusion phecode
509.1 Respiratory failure Respiratory 1.21 1.16 – 1.27 9.15e-15 1740 19285 exclusion phecode
509.2 Respiratory insufficiency Respiratory 1.24 1.18 – 1.31 1.39e-15 1529 16876 exclusion phecode
509.5 Respiratory arrest Respiratory 1.07 0.894 – 1.28 0.463 127 1341 exclusion phecode
509.8
Dependence on respirator [Ventilator] or
Dependence on respirator [Ventilator] or supplemental oxygen
 Respiratory 1.19 1.06 – 1.34 0.00288 316 3606 exclusion phecode
510 Other diseases of lung Respiratory 1.09 1.01 – 1.18 0.025 678 7063 exclusion phecode
512 Other symptoms of respiratory system Respiratory 1.15 1.13 – 1.18 9.67e-35 7972 85020 exclusion phecode
512.1 Wheezing Respiratory 1.25 1.08 – 1.46 0.00279 191 2053 exclusion phecode
512.2 Painful respiration Respiratory 1.14 0.988 – 1.33 0.0714 199 1962 exclusion phecode
512.7 Shortness of breath Respiratory 1.18 1.15 – 1.22 3.23e-30 5100 55012 exclusion phecode
512.8 Cough Respiratory 1.13 1.09 – 1.18 1.88e-09 2587 26966 exclusion phecode
512.9 Other dyspnea Respiratory 1.11 1.03 – 1.19 0.00736 787 8567 exclusion phecode
513 Respiratory abnormalities Respiratory 1.2 1.1 – 1.32 5.79e-05 522 5717 exclusion phecode
513.3 Hypoventilation Respiratory 1.59 1.23 – 2.05 0.000418 57 776 exclusion phecode
513.4 Hyperventilation Respiratory 1.27 1.11 – 1.44 0.000396 252 2633 exclusion phecode
513.8 Disorders of diaphragm Respiratory 1.18 0.991 – 1.41 0.0625 134 1427 exclusion phecode
514 Abnormal findings examination of lungs Respiratory 1.11 1.06 – 1.16 6.27e-06 2225 22934 exclusion phecode
516 Abnormal sputum Respiratory 1.16 1.11 – 1.21 6.91e-10 1893 19892 exclusion phecode
516.1 Hemoptysis Respiratory 1.15 1.1 – 1.21 9.6e-09 1838 19364 exclusion phecode
519
Other diseases of respiratory system, not
Other diseases of respiratory system, not elsewhere classified
 Respiratory 1.13 1.11 – 1.16 5.53e-27 8205 87976 exclusion phecode
519.2 Respiratory complications Respiratory 1.21 1.07 – 1.36 0.00199 287 3066 exclusion phecode
519.8 Other diseases of respiratory system, NEC Respiratory 1.13 1.11 – 1.16 2.01e-26 7743 83171 exclusion phecode
519.9
Symptoms involving respiratory system and other
Symptoms involving respiratory system and other chest symptoms
 Respiratory 0.959 0.851 – 1.08 0.489 285 2872 exclusion phecode
520 Disorders of tooth development Digestive 1.01 0.964 – 1.06 0.672 1937 19484 exclusion phecode
520.1 Hereditary disturbances in tooth structure Digestive 0.927 0.701 – 1.23 0.598 50 512 exclusion phecode
520.2 Disturbances in tooth eruption Digestive 1.01 0.967 – 1.06 0.646 2249 22566 exclusion phecode
521 Diseases of hard tissues of teeth Digestive 1.12 1.08 – 1.17 1.28e-08 2715 28722 exclusion phecode
521.1 Dental caries Digestive 1.12 1.08 – 1.17 1.11e-08 2724 28828 exclusion phecode
522 Diseases of pulp and periapical tissues Digestive 1.06 1.01 – 1.12 0.0242 1665 16910 exclusion phecode
522.5 Periapical abscess Digestive 1.09 1.03 – 1.16 0.00623 1089 11171 exclusion phecode
523 Gingival and periodontal diseases Digestive 1.04 0.992 – 1.1 0.0976 1574 16027 exclusion phecode
523.1 Gingivitis Digestive 1.01 0.826 – 1.23 0.945 109 1073 exclusion phecode
523.3 Periodontitis (acute or chronic) Digestive 1.02 0.963 – 1.09 0.455 1110 11138 exclusion phecode
523.31 Acute periodontitis Digestive 1.02 0.94 – 1.11 0.628 636 6402 exclusion phecode
523.32 Chronic periodontitis Digestive 1.05 0.957 – 1.14 0.32 534 5310 exclusion phecode
524 Dentofacial anomalies, including malocclusion Digestive 1.06 0.944 – 1.19 0.33 319 3167 exclusion phecode
524.3 Anomalies of tooth position/malocclusion Digestive 1 0.891 – 1.13 0.972 294 2909 exclusion phecode
525
Other diseases of the teeth and supporting
Other diseases of the teeth and supporting structures
 Digestive 1.07 1.03 – 1.12 0.00101 2453 25252 exclusion phecode
525.2 Atrophy of edentulous alveolar ridge Digestive 1.03 0.801 – 1.32 0.828 68 675 exclusion phecode
526 Diseases of the jaws Digestive 1.1 1.03 – 1.18 0.00484 877 8840 exclusion phecode
526.1 Cysts of the jaws Digestive 1.11 0.985 – 1.24 0.0893 306 3125 exclusion phecode
526.3 Anomalies of jaw size/symmetry Digestive 1.21 0.937 – 1.55 0.147 59 588 exclusion phecode
526.4 Temporomandibular joint disorders Digestive 1.06 0.929 – 1.21 0.392 232 2317 exclusion phecode
526.41 Temporomandibular joint disorder, unspecified Digestive 1.08 0.945 – 1.23 0.261 225 2252 exclusion phecode
526.5 Inflammatory conditions of jaw Digestive 0.991 0.811 – 1.21 0.928 101 1048 exclusion phecode
526.9 Jaw disease NOS Digestive 1.19 1.03 – 1.36 0.0142 221 2187 exclusion phecode
527 Diseases of the salivary glands Digestive 1.11 1.03 – 1.21 0.0107 631 6570 exclusion phecode
527.1 Hypertrophy of salivary gland Digestive 1.43 1.13 – 1.8 0.00295 77 790 exclusion phecode
527.2 Sialoadenitis Digestive 1.07 0.953 – 1.19 0.259 331 3475 exclusion phecode
527.7 Disturbance of salivary secretion Digestive 1.16 0.891 – 1.52 0.268 58 585 exclusion phecode
527.8 Other specified diseases of the salivary glands Digestive 1.09 0.889 – 1.32 0.421 114 1130 exclusion phecode
528
Diseases of the oral soft tissues, excluding
Diseases of the oral soft tissues, excluding lesions specific for gingiva and tongue
 Digestive 1.06 1.03 – 1.1 0.000356 3592 36647 exclusion phecode
528.1 Stomatitis and mucositis Digestive 1.03 0.931 – 1.13 0.586 426 4417 exclusion phecode
528.11 Stomatitis and mucositis (ulcerative) Digestive 1.06 0.947 – 1.18 0.33 354 3675 exclusion phecode
528.12 Oral aphthae Digestive 0.943 0.753 – 1.18 0.609 76 795 exclusion phecode
528.3 Cellulitis and abscess of oral soft tissues Digestive 1.05 0.889 – 1.23 0.585 161 1693 exclusion phecode
528.4 Cysts of oral soft tissues Digestive 1.04 0.866 – 1.25 0.684 119 1152 exclusion phecode
528.41 Cyst of the salivary gland Digestive 1.01 0.813 – 1.25 0.947 92 889 exclusion phecode
528.5 Diseases of lips Digestive 1.05 0.967 – 1.13 0.257 648 6442 exclusion phecode
528.6 Leukoplakia of oral mucosa Digestive 1.2 1.07 – 1.36 0.00258 282 2915 exclusion phecode
528.7 Sialolithiasis Digestive 1.02 0.905 – 1.15 0.743 288 2949 exclusion phecode
529 Diseases and other conditions of the tongue Digestive 1.05 0.983 – 1.11 0.157 1127 11615 exclusion phecode
529.1 Glossitis Digestive 1.16 1.03 – 1.32 0.0164 269 2816 exclusion phecode
530 Diseases of esophagus Digestive 1.11 1.1 – 1.13 4.84e-70 30729 264360 exclusion phecode
530.1 Esophagitis, GERD and related diseases Digestive 1.11 1.1 – 1.13 2.91e-67 28746 257848 exclusion phecode
530.11 GERD Digestive 1.11 1.1 – 1.13 8.05e-50 20933 213547 exclusion phecode
530.12 Ulcer of esophagus Digestive 1.11 1.08 – 1.15 8.66e-13 4732 48651 exclusion phecode
530.14 Reflux esophagitis Digestive 1.11 1.09 – 1.14 1.14e-23 9652 98531 exclusion phecode
530.2 Esophageal bleeding (varices/hemorrhage) Digestive 1.12 1.07 – 1.19 2.02e-05 1449 15782 exclusion phecode
530.3 Stricture and stenosis of esophagus Digestive 1.05 0.995 – 1.1 0.0786 1716 17450 exclusion phecode
530.5 Disorders of esophageal motility Digestive 1.09 1 – 1.19 0.0446 591 6027 exclusion phecode
530.6 Diverticulum of esophagus, acquired Digestive 1.09 0.918 – 1.3 0.315 141 1432 exclusion phecode
530.7 Gastroesophageal laceration-hemorrhage syndrome Digestive 1.16 1.03 – 1.31 0.0131 307 3240 exclusion phecode
530.9 Heartburn Digestive 1.08 1.03 – 1.13 0.00135 1963 19749 exclusion phecode
531 Peptic ulcer (excl. esophageal) Digestive 1.13 1.1 – 1.16 1.51e-21 6334 66470 exclusion phecode
531.1 Hemorrhage from gastrointestinal ulcer Digestive 1.07 0.981 – 1.16 0.131 576 5886 exclusion phecode
531.2 Gastric ulcer Digestive 1.12 1.08 – 1.16 1.6e-10 3616 38404 exclusion phecode
531.3 Duodenal ulcer Digestive 1.16 1.12 – 1.21 1.05e-13 2710 27967 exclusion phecode
531.4 Peptic ulcer, site unspecified Digestive 1.28 1.15 – 1.42 5.25e-06 378 3960 exclusion phecode
532 Dysphagia Digestive 1.08 1.05 – 1.1 1.01e-07 5929 60706 exclusion phecode
535 Gastritis and duodenitis Digestive 1.11 1.09 – 1.12 1.16e-55 25512 247401 exclusion phecode
535.1 Acute gastritis Digestive 1.17 1.09 – 1.24 2.48e-06 1043 11095 exclusion phecode
535.2 Atrophic gastritis Digestive 1.17 1.04 – 1.3 0.00724 332 3460 exclusion phecode
535.6 Duodenitis Digestive 1.13 1.11 – 1.16 1.45e-23 6866 71419 exclusion phecode
535.8 Other specified gastritis Digestive 1.11 1.08 – 1.13 1.15e-16 7303 76187 exclusion phecode
535.9 Gastritis and duodenitis, NOS Digestive 1.12 0.92 – 1.36 0.261 111 1112 exclusion phecode
536.8
Dyspepsia and other specified disorders of
Dyspepsia and other specified disorders of function of stomach
 Digestive 0.974 0.853 – 1.11 0.691 237 2437 exclusion phecode
537 Other disorders of stomach and duodenum Digestive 1.13 1.09 – 1.18 3.79e-11 3017 31937 exclusion phecode
540 Appendiceal conditions Digestive 1.05 1.01 – 1.09 0.0116 2946 29333 exclusion phecode
540.1 Appendicitis Digestive 1.05 1.01 – 1.09 0.0143 2768 27499 exclusion phecode
540.11 Acute appendicitis Digestive 1.03 0.988 – 1.07 0.168 2486 24685 exclusion phecode
550 Abdominal hernia Digestive 1.07 1.06 – 1.08 7.9e-38 42036 267890 exclusion phecode
550.1 Inguinal hernia Digestive 0.989 0.972 – 1.01 0.208 15043 114143 exclusion phecode
550.2 Diaphragmatic hernia Digestive 1.11 1.1 – 1.13 3.86e-56 24303 225693 exclusion phecode
550.3 Femoral hernia Digestive 0.931 0.858 – 1.01 0.0906 643 6178 exclusion phecode
550.4 Umbilical hernia Digestive 1.11 1.07 – 1.15 2.98e-08 3231 34608 exclusion phecode
550.5 Ventral hernia Digestive 1.13 1.09 – 1.18 1.65e-11 3094 32276 exclusion phecode
555
Inflammatory bowel disease and other
Inflammatory bowel disease and other gastroenteritis and colitis
 Digestive 1.08 1.05 – 1.12 1.08e-06 4110 42198 exclusion phecode
555.1 Regional enteritis Digestive 1.12 1.07 – 1.18 1.16e-05 1615 16508 exclusion phecode
555.2 Ulcerative colitis Digestive 1.07 1.03 – 1.11 8e-04 2925 30119 exclusion phecode
555.21 Ulcerative colitis (chronic) Digestive 1.07 0.977 – 1.18 0.143 500 5102 exclusion phecode
556 Ulceration of the lower GI tract Digestive 1.14 1.07 – 1.22 8.5e-05 980 10066 exclusion phecode
556.1 Ulceration of intestine Digestive 1.11 1.03 – 1.21 0.0102 624 6385 exclusion phecode
557 Intestinal malabsorption (non-celiac) Digestive 0.999 0.883 – 1.13 0.985 269 2867 exclusion phecode
557.1 Celiac disease Digestive 1.12 1.06 – 1.17 1.72e-05 1728 17479 exclusion phecode
558 Noninfectious gastroenteritis Digestive 1.1 1.08 – 1.11 1.37e-24 13933 147608 exclusion phecode
559 Ileostomy status Digestive 1.06 1.01 – 1.12 0.0314 1505 15646 exclusion phecode
560 Intestinal obstruction without mention of hernia Digestive 1.05 1.01 – 1.08 0.00788 3625 37175 exclusion phecode
560.1 Paralytic ileus Digestive 1.12 1.02 – 1.23 0.0223 475 4886 exclusion phecode
560.2 Impaction of intestine Digestive 0.978 0.859 – 1.11 0.741 245 2535 exclusion phecode
560.3 Peritoneal or intestinal adhesions Digestive 1.09 1.01 – 1.17 0.0287 773 7898 exclusion phecode
560.4 Other intestinal obstruction Digestive 1.04 1.01 – 1.08 0.0241 3106 31745 exclusion phecode
561 Symptoms involving digestive system Digestive 1.06 1.04 – 1.07 6.52e-10 14628 150168 exclusion phecode
561.1 Diarrhea Digestive 1.13 1.02 – 1.25 0.016 442 4407 exclusion phecode
561.2 Flatulence Digestive 1.09 1.04 – 1.15 0.000667 1577 16031 exclusion phecode
562 Diverticulosis and diverticulitis Digestive 1.08 1.07 – 1.1 8.39e-31 24336 200327 exclusion phecode
562.1 Diverticulosis Digestive 1.08 1.07 – 1.1 1.07e-30 24304 200278 exclusion phecode
563 Constipation Digestive 1.08 1.06 – 1.1 8.92e-13 9388 97782 exclusion phecode
564 Functional digestive disorders Digestive 1.12 1.1 – 1.14 7.6e-51 19892 199204 exclusion phecode
564.1 Irritable Bowel Syndrome Digestive 1.12 1.09 – 1.15 2.17e-14 5125 52788 exclusion phecode
564.8
Abnormal findings on exam of gastrointestinal
Abnormal findings on exam of gastrointestinal tract/ abdominal area
 Digestive 1.09 1.04 – 1.15 0.00115 1506 15594 exclusion phecode
564.9 Personal history of diseases of digestive system Digestive 1.13 1.11 – 1.15 2.24e-43 13876 143160 exclusion phecode
565 Anal and rectal conditions Digestive 1.07 1.05 – 1.09 1.75e-13 13575 138890 exclusion phecode
565.1 Anal and rectal polyp Digestive 1.06 1.04 – 1.09 9.55e-07 6731 68946 exclusion phecode
567 Peritonitis and retroperitoneal infections Digestive 1.09 1.02 – 1.17 0.0143 807 8736 exclusion phecode
568 Other disorders of peritoneum Digestive 1.13 1.09 – 1.17 1.16e-10 3010 30910 exclusion phecode
568.1
Peritoneal adhesions (postoperative)
Peritoneal adhesions (postoperative) (postinfection)
 Digestive 1.13 1.09 – 1.17 5.43e-10 2863 29370 exclusion phecode
569 Other disorders of intestine Digestive 1.06 1.02 – 1.09 0.00104 3781 39469 exclusion phecode
569.1 Toxic gastroenteritis and colitis Digestive 1.05 0.878 – 1.26 0.583 130 1387 exclusion phecode
569.2 Gastrointestinal complications Digestive 0.997 0.906 – 1.1 0.952 452 4552 exclusion phecode
571 Chronic liver disease and cirrhosis Digestive 1.32 1.26 – 1.37 1.21e-37 2298 27875 exclusion phecode
571.5 Other chronic nonalcoholic liver disease Digestive 1.47 1.39 – 1.56 8.61e-41 1276 15957 exclusion phecode
571.51 Cirrhosis of liver without mention of alcohol Digestive 1.28 1.03 – 1.58 0.0235 85 1064 exclusion phecode
571.6 Primary biliary cirrhosis Digestive 1.19 1.04 – 1.36 0.0114 235 2450 exclusion phecode
571.8
Liver abscess and sequelae of chronic liver
Liver abscess and sequelae of chronic liver disease
 Digestive 1.17 1.09 – 1.26 3.06e-05 752 9194 exclusion phecode
571.81 Portal hypertension Digestive 1.29 1.16 – 1.43 1.39e-06 380 4962 exclusion phecode
572 Ascites (non malignant) Digestive 1.16 1.09 – 1.22 4.61e-07 1327 14521 exclusion phecode
573 Other disorders of liver Digestive 1.13 1.07 – 1.19 3.07e-05 1341 14109 exclusion phecode
573.2 Liver replaced by transplant Digestive 1.42 1.12 – 1.8 0.00423 72 901 exclusion phecode
573.3 Hepatomegaly Digestive 1.18 1.04 – 1.35 0.0118 244 2785 exclusion phecode
573.5 Jaundice (not of newborn) Digestive 1.13 1.05 – 1.22 0.000962 798 8392 exclusion phecode
573.7 Abnormal results of function study of liver Digestive 1.16 1.12 – 1.2 6.58e-15 3027 32618 exclusion phecode
573.9 Abnormal serum enzyme levels Digestive 1.11 0.952 – 1.29 0.183 182 1938 exclusion phecode
574 Cholelithiasis and cholecystitis Digestive 1.17 1.15 – 1.19 1.06e-72 14237 148220 exclusion phecode
574.1 Cholelithiasis Digestive 1.16 1.14 – 1.19 2.49e-58 12362 128746 exclusion phecode
574.11 Cholelithiasis with acute cholecystitis Digestive 1.23 1.16 – 1.3 4.27e-13 1362 14233 exclusion phecode
574.12 Cholelithiasis with other cholecystitis Digestive 1.18 1.15 – 1.22 1.12e-29 4994 51608 exclusion phecode
574.2 Calculus of bile duct Digestive 1.2 1.15 – 1.26 5.54e-18 2397 24744 exclusion phecode
574.3 Cholecystitis without cholelithiasis Digestive 1.25 1.2 – 1.31 1.54e-26 2453 26038 exclusion phecode
575 Other biliary tract disease Digestive 1.18 1.14 – 1.22 3.2e-20 3517 36487 exclusion phecode
575.1 Cholangitis Digestive 1.24 1.12 – 1.36 1.41e-05 439 4584 exclusion phecode
575.2 Obstruction of bile duct Digestive 1.15 1.06 – 1.24 0.000568 687 7223 exclusion phecode
575.6 Cholesterolosis of gallbladder Digestive 1.3 1.18 – 1.44 1.94e-07 429 4368 exclusion phecode
575.7 Other disorders of gallbladder Digestive 1.22 1.15 – 1.29 1.39e-11 1296 13362 exclusion phecode
575.8 Other disorders of biliary tract Digestive 1.13 1.05 – 1.2 0.000441 937 9770 exclusion phecode
575.9
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of biliary tract
 Digestive 1.11 0.991 – 1.25 0.0697 311 3264 exclusion phecode
577 Diseases of pancreas Digestive 1.22 1.17 – 1.28 3.17e-20 2318 25039 exclusion phecode
577.1 Acute pancreatitis Digestive 1.24 1.18 – 1.3 3.24e-17 1749 18760 exclusion phecode
577.2 Chronic pancreatitis Digestive 1.48 1.34 – 1.65 1.69e-13 402 4821 exclusion phecode
577.3 Cyst and pseudocyst of pancreas Digestive 1.28 1.14 – 1.44 2.7e-05 306 3419 exclusion phecode
578 Gastrointestinal hemorrhage Digestive 1.07 1.05 – 1.09 5.35e-19 19004 194935 exclusion phecode
578.1 Hematemesis Digestive 1.15 1.1 – 1.21 1.64e-08 1710 18403 exclusion phecode
578.2 Blood in stool Digestive 1.13 1.08 – 1.17 4.74e-08 2348 24635 exclusion phecode
578.8 Hemorrhage of rectum and anus Digestive 1.06 1.04 – 1.08 3.09e-10 12141 123882 exclusion phecode
578.9 Hemorrhage of gastrointestinal tract Digestive 1.06 1.03 – 1.1 4.85e-05 4852 49810 exclusion phecode
579 Other symptoms involving abdomen and pelvis Digestive 1.05 0.992 – 1.11 0.0952 1360 14667 exclusion phecode
579.2 Splenomegaly Digestive 1.06 0.944 – 1.18 0.337 332 3963 exclusion phecode
579.8 Nonspecific abnormal findings in stool contents Digestive 1.05 0.997 – 1.11 0.0644 1505 15642 exclusion phecode
580 Nephritis; nephrosis; renal sclerosis Genitourinary 1.17 1.1 – 1.25 5.27e-07 1062 14380 exclusion phecode
580.1 Glomerulonephritis Genitourinary 1.21 1.13 – 1.3 1.97e-07 790 9865 exclusion phecode
580.11 Proliferative glomerulonephritis Genitourinary 1.22 0.947 – 1.57 0.124 65 695 exclusion phecode
580.12 Non-proliferative glomerulonephritis Genitourinary 1.22 1.01 – 1.47 0.0379 120 1288 exclusion phecode
580.14 Chronic glomerulonephritis, NOS Genitourinary 1.19 1.1 – 1.29 1.98e-05 634 8183 exclusion phecode
580.2
Nephrotic syndrome without mention of
Nephrotic syndrome without mention of glomerulonephritis
 Genitourinary 1.15 1.01 – 1.32 0.0335 227 4397 exclusion phecode
580.3
Nephritis and nephropathy without mention of
Nephritis and nephropathy without mention of glomerulonephritis
 Genitourinary 1.07 0.929 – 1.24 0.34 204 2328 exclusion phecode
580.32
Nephritis and nephropathy with pathological
Nephritis and nephropathy with pathological lesion
 Genitourinary 1.06 0.917 – 1.22 0.441 207 2397 exclusion phecode
585 Renal failure Genitourinary 1.16 1.13 – 1.19 2.26e-25 5425 64995 exclusion phecode
585.1 Acute renal failure Genitourinary 1.14 1.11 – 1.19 1.42e-14 3464 42142 exclusion phecode
585.2 Renal failure NOS Genitourinary 1.13 1.06 – 1.19 6.64e-05 1172 13634 exclusion phecode
585.3 Chronic renal failure [CKD] Genitourinary 1.22 1.17 – 1.28 2.49e-17 1923 24661 exclusion phecode
585.31 Renal dialysis Genitourinary 1.16 1.04 – 1.29 0.00569 380 4640 exclusion phecode
586 Other disorders of the kidney and ureters Genitourinary 1.08 1.04 – 1.13 2.49e-05 2972 31547 exclusion phecode
586.1 Anatomical abnormatilies of kidney and ureters Genitourinary 1.15 0.984 – 1.34 0.0795 185 1974 exclusion phecode
586.11 Small kidney Genitourinary 1.15 0.977 – 1.36 0.093 157 1701 exclusion phecode
586.2 Cyst of kidney, acquired Genitourinary 1.1 1.03 – 1.17 0.00263 1135 11756 exclusion phecode
586.3 Vascular disorders of kidney/hypertrophy Genitourinary 1.12 0.874 – 1.44 0.371 70 747 exclusion phecode
586.4 Stricture/obstruction of ureter Genitourinary 1.07 0.998 – 1.15 0.0582 818 8584 exclusion phecode
587 Kidney replaced by transpant Genitourinary 1.04 0.929 – 1.17 0.471 307 3498 exclusion phecode
588 Disorders resulting from impaired renal function Genitourinary 1.06 0.835 – 1.34 0.633 78 923 exclusion phecode
589 Abnormal results of function study of kidney Genitourinary 1.01 0.816 – 1.24 0.948 94 1096 exclusion phecode
590 Pyelonephritis Genitourinary 1.16 1.1 – 1.24 4.96e-07 1180 12664 exclusion phecode
591 Urinary tract infection Genitourinary 1.08 1.06 – 1.1 8.11e-14 10956 116943 exclusion phecode
592 Cystitis and urethritis Genitourinary 1.06 1.02 – 1.1 0.00586 2703 28064 exclusion phecode
592.1 Cystitis Genitourinary 1.06 1.02 – 1.1 0.00302 2647 27483 exclusion phecode
592.11 Acute cystitis Genitourinary 0.892 0.745 – 1.07 0.216 127 1288 exclusion phecode
592.12 Chronic cystitis Genitourinary 1.05 0.981 – 1.13 0.156 809 8385 exclusion phecode
592.13 Chronic interstitial cystitis Genitourinary 1.01 0.886 – 1.16 0.857 234 2359 exclusion phecode
592.2 Urethritis and urethral syndrome Genitourinary 0.952 0.807 – 1.12 0.563 152 1577 exclusion phecode
593 Hematuria Genitourinary 1.06 1.05 – 1.08 7.15e-13 14660 150490 exclusion phecode
594 Urinary calculus Genitourinary 1.12 1.09 – 1.15 8.74e-16 5637 59787 exclusion phecode
594.1 Calculus of kidney Genitourinary 1.11 1.07 – 1.16 8.71e-08 2770 29764 exclusion phecode
594.2 Calculus of lower urinary tract Genitourinary 1.16 1.07 – 1.26 0.000233 676 7198 exclusion phecode
594.3 Calculus of ureter Genitourinary 1.09 1.04 – 1.14 0.000304 2104 22472 exclusion phecode
594.8 Renal colic Genitourinary 1.12 1.07 – 1.17 3.41e-06 1830 19298 exclusion phecode
595 Hydronephrosis Genitourinary 1.08 1.03 – 1.14 0.00141 1708 18144 exclusion phecode
596 Other disorders of bladder Genitourinary 1.06 1.04 – 1.08 1.56e-07 8894 91056 exclusion phecode
596.1 Bladder neck obstruction Genitourinary 1.03 0.977 – 1.08 0.303 1785 18071 exclusion phecode
596.5 Functional disorders of bladder Genitourinary 1.06 1.01 – 1.12 0.0228 1505 15631 exclusion phecode
597 Other disorders of urethra and urinary tract Genitourinary 1.09 1.05 – 1.13 1.46e-06 3558 36701 exclusion phecode
597.1 Urethral stricture (not specified as infectious) Genitourinary 1.09 1.05 – 1.13 6.96e-06 3002 31026 exclusion phecode
597.2 Urinary complications NEC Genitourinary 1.1 0.866 – 1.4 0.438 67 728 exclusion phecode
598 Abnormal findings on examination of urine Genitourinary 1.03 0.996 – 1.07 0.0833 3201 32890 exclusion phecode
598.9
Other nonspecific findings on examination of
Other nonspecific findings on examination of urine
 Genitourinary 0.983 0.869 – 1.11 0.787 270 2848 exclusion phecode
599 Other symptoms/disorders or the urinary system Genitourinary 1.09 1.07 – 1.1 4.17e-25 16879 174093 exclusion phecode
599.1 Urinary obstruction Genitourinary 1.02 0.862 – 1.21 0.808 141 1543 exclusion phecode
599.2 Retention of urine Genitourinary 1.09 1.06 – 1.12 2.05e-10 6033 62088 exclusion phecode
599.3 Dysuria Genitourinary 1.08 1.01 – 1.14 0.0215 1082 11281 exclusion phecode
599.4 Urinary incontinence Genitourinary 1.11 1.09 – 1.14 2.53e-20 8118 83676 exclusion phecode
599.5 Frequency of urination and polyuria Genitourinary 1.05 1.02 – 1.09 0.00293 3641 37653 exclusion phecode
599.6 Oliguria and anuria Genitourinary 1.04 0.838 – 1.28 0.745 84 989 exclusion phecode
599.8 Other symptoms involving urinary system Genitourinary 1.13 0.867 – 1.48 0.358 60 577 exclusion phecode
599.9 Other abnormality of urination Genitourinary 1.08 1.03 – 1.14 0.00154 1726 17873 exclusion phecode
600 Hyperplasia of prostate Genitourinary 1.05 1.03 – 1.07 6.94e-06 9996 80373 exclusion phecode
601 Inflammatory diseases of prostate Genitourinary 1.07 1.02 – 1.12 0.00446 1876 19115 exclusion phecode
601.1 Prostatitis Genitourinary 1.06 1.01 – 1.12 0.0212 1456 14346 exclusion phecode
601.11 Acute prostatitis Genitourinary 1.06 0.919 – 1.22 0.436 214 2159 exclusion phecode
601.12 Chronic prostatitis Genitourinary 1.03 0.956 – 1.1 0.485 838 8250 exclusion phecode
601.3 Orchitis and epididymitis Genitourinary 0.945 0.716 – 1.25 0.693 55 543 exclusion phecode
601.4 Balanoposthitis Genitourinary 1.07 0.934 – 1.22 0.336 227 2628 exclusion phecode
601.8
Other inflammatory disorders of male genital
Other inflammatory disorders of male genital organs
 Genitourinary 1.13 0.989 – 1.28 0.0722 259 2786 exclusion phecode
602 Other disorders of prostate Genitourinary 1.05 0.993 – 1.12 0.0837 1216 12179 exclusion phecode
603 Other disorders of testis Genitourinary 1.09 1.04 – 1.14 0.000344 1921 19960 exclusion phecode
603.1 Hydrocele Genitourinary 1.09 1.03 – 1.16 0.00259 1197 12347 exclusion phecode
604 Disorders of penis Genitourinary 1.06 1.02 – 1.11 0.00153 2786 30489 exclusion phecode
604.1 Redundant prepuce and phimosis/BXO Genitourinary 1.07 1.03 – 1.12 0.00115 2287 25254 exclusion phecode
605 Erectile dysfunction [ED] Genitourinary 1.12 0.974 – 1.28 0.115 222 2516 exclusion phecode
608 Other disorders of male genital organs Genitourinary 1.03 0.994 – 1.08 0.0972 2616 26196 exclusion phecode
609 Male infertility and abnormal spermatozoa Genitourinary 0.998 0.859 – 1.16 0.975 190 1955 exclusion phecode
609.1 Infertility, male Genitourinary 0.837 0.639 – 1.1 0.194 57 604 exclusion phecode
609.2 Abnormal spermatozoa Genitourinary 1.03 0.869 – 1.22 0.745 149 1527 exclusion phecode
610 Benign mammary dysplasias Genitourinary 0.985 0.944 – 1.03 0.5 2382 23939 exclusion phecode
610.1 Cystic mastopathy Genitourinary 0.919 0.856 – 0.985 0.0176 886 8911 exclusion phecode
610.2 Fibroadenosis of breast Genitourinary 1 0.889 – 1.13 0.955 293 2939 exclusion phecode
610.3 Fibrosclerosis of breast Genitourinary 1.01 0.895 – 1.14 0.875 292 2908 exclusion phecode
610.4 Benign neoplasm of breast Genitourinary 0.981 0.926 – 1.04 0.498 1341 13391 exclusion phecode
610.8 Other specified benign mammary dysplasias Genitourinary 1.08 0.998 – 1.18 0.056 648 6695 exclusion phecode
611 Abnormal findings on mammogram or breast exam Genitourinary 1 0.95 – 1.06 0.927 1509 15151 exclusion phecode
611.1 Abnormal mammogram Genitourinary 1.11 0.845 – 1.45 0.458 56 543 exclusion phecode
611.3 Lump or mass in breast Genitourinary 1 0.951 – 1.06 0.863 1458 14671 exclusion phecode
612
Breast conditions, congenital or relating to
Breast conditions, congenital or relating to hormones
 Genitourinary 1.16 1.08 – 1.24 4.99e-05 834 8530 exclusion phecode
612.2 Hypertrophy of breast (Gynecomastia) Genitourinary 1.14 1.06 – 1.22 0.000488 792 8135 exclusion phecode
612.3 Congenital anomalies of breast Genitourinary 1.13 0.896 – 1.43 0.297 72 702 exclusion phecode
613 Other nonmalignant breast conditions Genitourinary 1.07 1.02 – 1.13 0.0105 1562 15868 exclusion phecode
613.1 Inflammatory disease of breast Genitourinary 1.09 1.01 – 1.18 0.0362 681 6902 exclusion phecode
613.5 Mastodynia Genitourinary 1.15 0.9 – 1.47 0.264 71 740 exclusion phecode
613.7 Other signs and symptoms in breast Genitourinary 0.965 0.89 – 1.05 0.383 674 6734 exclusion phecode
613.8 Other specified disorders of breast Genitourinary 1.05 0.933 – 1.18 0.424 308 3153 exclusion phecode
613.9 Breast disorder NOS Genitourinary 0.987 0.852 – 1.14 0.86 195 1993 exclusion phecode
614 Inflammatory diseases of female pelvic organs Genitourinary 1.07 1.04 – 1.1 4.13e-06 5440 55217 exclusion phecode
614.1
Pelvic peritoneal adhesions, female
Pelvic peritoneal adhesions, female (postoperative) (postinfection)
 Genitourinary 1.11 1.06 – 1.16 1.31e-06 2415 24562 exclusion phecode
614.3 Pelvic inflammatory disease (PID) Genitourinary 1.08 1 – 1.16 0.0468 786 8054 exclusion phecode
614.31 Acute inflammatory pelvic disease Genitourinary 1.3 0.995 – 1.69 0.0546 58 589 exclusion phecode
614.32 Chronic inflammatory pelvic disease Genitourinary 1.08 0.975 – 1.2 0.14 401 4085 exclusion phecode
614.33 Pelvic inflammatory disease, NOS Genitourinary 1.01 0.906 – 1.13 0.813 331 3406 exclusion phecode
614.4 Inflammatory diseases of uterus, except cervix Genitourinary 1.03 0.903 – 1.16 0.694 260 2681 exclusion phecode
614.5
Inflammatory disease of cervix, vagina, and
Inflammatory disease of cervix, vagina, and vulva
 Genitourinary 1.04 0.993 – 1.08 0.0991 2489 25106 exclusion phecode
614.51 Cervicitis and endocervicitis Genitourinary 1.01 0.953 – 1.07 0.732 1273 12705 exclusion phecode
614.52 Vaginitis and vulvovaginitis Genitourinary 1.15 1.03 – 1.27 0.00962 400 4104 exclusion phecode
614.53 Cyst or abscess of Bartholin's gland Genitourinary 0.966 0.896 – 1.04 0.38 738 7335 exclusion phecode
614.54 Abscess or ulceration of vulva Genitourinary 1.1 0.966 – 1.26 0.145 239 2637 exclusion phecode
615 Endometriosis Genitourinary 1.1 1.06 – 1.13 4.54e-08 3889 39090 exclusion phecode
617
Disorders secondary to childbirth, surgery
Disorders secondary to childbirth, surgery, trauma
 Genitourinary 1.01 0.896 – 1.14 0.853 282 2913 exclusion phecode
618 Genital prolapse Genitourinary 1.07 1.05 – 1.09 5.11e-12 11118 112036 exclusion phecode
618.1 Prolapse of vaginal walls Genitourinary 1.08 1.06 – 1.11 3.13e-10 7003 70837 exclusion phecode
618.2 Uterine/Uterovaginal prolapse Genitourinary 1.06 1.03 – 1.09 4.43e-05 5155 51655 exclusion phecode
618.5 Prolapse of vaginal vault after hysterectomy Genitourinary 1.12 1.02 – 1.23 0.0204 486 4904 exclusion phecode
618.6 Vaginal enterocele, congenital or acquired Genitourinary 1.11 1.02 – 1.2 0.0158 644 6499 exclusion phecode
619 Noninflammatory female genital disorders Genitourinary 1.06 1.03 – 1.08 1.83e-06 8363 84184 exclusion phecode
619.1
Noninflammatory disorders of ovary, fallopian
Noninflammatory disorders of ovary, fallopian tube, and broad ligament
 Genitourinary 1.07 0.986 – 1.15 0.106 693 7033 exclusion phecode
619.2 Disorders of uterus, NEC Genitourinary 1.05 1.01 – 1.09 0.0103 3193 32009 exclusion phecode
619.3 Noninflammatory disorders of cervix Genitourinary 1.06 1.02 – 1.1 0.00359 2749 27642 exclusion phecode
619.4 Noninflammatory disorders of vagina Genitourinary 1.01 0.958 – 1.06 0.765 1677 17029 exclusion phecode
619.5 Noninflammatory disorders of vulva and perineum Genitourinary 1.04 0.985 – 1.1 0.149 1300 13027 exclusion phecode
620 Dysplasia of female genital organs Genitourinary 1.18 0.937 – 1.48 0.16 69 696 exclusion phecode
621 Endometrial hyperplasia Genitourinary 1.11 1.04 – 1.19 0.00123 1039 10848 exclusion phecode
622 Polyp of female genital organs Genitourinary 1.04 1.02 – 1.06 0.000374 9968 100916 exclusion phecode
622.1 Polyp of corpus uteri Genitourinary 1.04 1.02 – 1.07 0.000847 7440 75629 exclusion phecode
622.2 Mucous polyp of cervix Genitourinary 0.997 0.962 – 1.03 0.872 3310 33101 exclusion phecode
623 Hypertrophy of female genital organs Genitourinary 1.05 0.985 – 1.11 0.139 1206 12258 exclusion phecode
624 Symptoms involving female genital tract Genitourinary 1.05 0.972 – 1.13 0.225 763 7635 exclusion phecode
624.1 Dystrophy of female genital tract Genitourinary 1.09 0.947 – 1.25 0.236 223 2263 exclusion phecode
624.2 Atrophy of female genital tract Genitourinary 1.07 0.965 – 1.18 0.203 424 4232 exclusion phecode
624.9 stress incontinence, female Genitourinary 1.13 1.1 – 1.16 4.87e-17 5523 56453 exclusion phecode
625
Pain and other symptoms associated with female
Pain and other symptoms associated with female genital organs
 Genitourinary 1.05 1.01 – 1.09 0.0183 2785 27865 exclusion phecode
625.1 Dyspareunia Genitourinary 1.01 0.946 – 1.07 0.855 1145 11517 exclusion phecode
626
Disorders of menstruation and other abnormal
Disorders of menstruation and other abnormal bleeding from female genital tract
 Genitourinary 1.08 1.06 – 1.1 8.08e-18 15528 111487 exclusion phecode
626.1 Irregular menstrual cycle/bleeding Genitourinary 1.09 1.07 – 1.11 3.06e-20 13545 106593 exclusion phecode
626.11 Absent or infrequent menstruation Genitourinary 1.09 0.894 – 1.33 0.39 104 1065 exclusion phecode
626.12 Excessive or frequent menstruation Genitourinary 1.1 1.07 – 1.12 1.82e-16 9300 88996 exclusion phecode
626.13 Irregular menstrual cycle Genitourinary 1.04 0.987 – 1.09 0.154 1893 19168 exclusion phecode
626.14 Irregular menstrual bleeding Genitourinary 1.08 1.05 – 1.12 5.18e-06 3672 36941 exclusion phecode
626.2 Dysmenorrhea Genitourinary 1.14 1.08 – 1.19 6.27e-07 1699 17257 exclusion phecode
626.4 Premenstrual tension syndromes Genitourinary 1.13 0.956 – 1.33 0.156 156 1546 exclusion phecode
626.8 Infertility, female Genitourinary 0.931 0.879 – 0.986 0.0149 1330 13255 exclusion phecode
627 Menopausal and postmenopausal disorders Genitourinary 1.05 1.03 – 1.07 1.74e-05 9793 99738 exclusion phecode
627.1 Postmenopausal bleeding Genitourinary 1.05 1.03 – 1.07 1.57e-05 8516 86721 exclusion phecode
627.2 Symptomatic menopause Genitourinary 1.2 1.02 – 1.4 0.0262 176 1772 exclusion phecode
627.3 Postmenopausal atrophic vaginitis Genitourinary 0.977 0.918 – 1.04 0.47 1065 10660 exclusion phecode
627.4 Premenopausal menorrhagia Genitourinary 1.05 0.927 – 1.18 0.463 289 2989 exclusion phecode
628 Ovarian cyst Genitourinary 1.09 1.06 – 1.12 4.4e-08 4542 45955 exclusion phecode
634 Miscarriage; stillbirth Pregnancy Complications 0.963 0.934 – 0.992 0.0127 5105 35607 exclusion phecode
634.1 Missed abortion/Hydatidiform mole Pregnancy Complications 0.938 0.882 – 0.997 0.0413 1111 11073 exclusion phecode
634.3 Ectopic pregnancy Pregnancy Complications 0.974 0.869 – 1.09 0.65 324 3241 exclusion phecode
635
Hemorrhage during pregnancy; childbirth and
Hemorrhage during pregnancy; childbirth and postpartum
 Pregnancy Complications 0.953 0.909 – 0.999 0.0472 1922 17014 exclusion phecode
635.2
Antepartum hemorrhage, abruptio placentae, and
Antepartum hemorrhage, abruptio placentae, and placenta previa
 Pregnancy Complications 0.909 0.846 – 0.976 0.00898 848 8440 exclusion phecode
635.3 Placenta previa and abruptio placenta Pregnancy Complications 0.959 0.905 – 1.02 0.166 1234 12059 exclusion phecode
636
Early or threatened labor; hemorrhage in early
Early or threatened labor; hemorrhage in early pregnancy
 Pregnancy Complications 0.984 0.941 – 1.03 0.459 2286 19568 exclusion phecode
636.2 Early onset of delivery Pregnancy Complications 0.941 0.864 – 1.02 0.163 593 6017 exclusion phecode
636.3 Hemorrhage in early pregnancy Pregnancy Complications 0.98 0.92 – 1.05 0.542 1049 10542 exclusion phecode
638 Other high-risk pregnancy Pregnancy Complications 0.855 0.663 – 1.1 0.226 67 686 exclusion phecode
642
Hypertension complicating pregnancy
Hypertension complicating pregnancy, childbirth, and the puerperium
 Pregnancy Complications 1.04 0.974 – 1.11 0.254 1053 10847 exclusion phecode
642.1 Preeclampsia and eclampsia Pregnancy Complications 0.955 0.847 – 1.08 0.457 289 2990 exclusion phecode
643 Excessive vomiting in pregnancy Pregnancy Complications 1.02 0.879 – 1.18 0.818 203 2106 exclusion phecode
643.1 Hyperemesis gravidarum Pregnancy Complications 0.966 0.814 – 1.15 0.691 145 1496 exclusion phecode
645 Late pregnancy and failed induction Pregnancy Complications 0.95 0.896 – 1.01 0.0912 1221 12220 exclusion phecode
646 Other complications of pregnancy NEC Pregnancy Complications 0.991 0.948 – 1.04 0.704 2148 20439 exclusion phecode
647
Infectious and parasitic complications
Infectious and parasitic complications affecting pregnancy
 Pregnancy Complications 1.11 0.865 – 1.43 0.41 68 663 exclusion phecode
647.1
Infections of genitourinary tract during
Infections of genitourinary tract during pregnancy
 Pregnancy Complications 0.966 0.848 – 1.1 0.595 268 2698 exclusion phecode
649
Other conditions or status of the mother
Other conditions or status of the mother complicating pregnancy, childbirth, or the puerperium
 Pregnancy Complications 0.791 0.645 – 0.969 0.0238 107 1112 exclusion phecode
649.1
Diabetes or abnormal glucose tolerance
Diabetes or abnormal glucose tolerance complicating pregnancy
 Pregnancy Complications 1.31 1 – 1.73 0.0485 50 1891 exclusion phecode
650 Normal delivery Pregnancy Complications 0.927 0.884 – 0.973 0.00201 1892 18558 exclusion phecode
651 Multiple gestation Pregnancy Complications 0.971 0.867 – 1.09 0.615 338 3390 exclusion phecode
652
Malposition and malpresentation of fetus or
Malposition and malpresentation of fetus or obstruction
 Pregnancy Complications 0.971 0.923 – 1.02 0.261 1675 16191 exclusion phecode
653
Problems associated with amniotic cavity and
Problems associated with amniotic cavity and membranes
 Pregnancy Complications 0.957 0.905 – 1.01 0.127 1371 13371 exclusion phecode
654
Other and unspecified complications of birth
Other and unspecified complications of birth; puerperium affecting management of mother
 Pregnancy Complications 0.995 0.781 – 1.27 0.967 72 727 exclusion phecode
655
Known or suspected fetal abnormality affecting
Known or suspected fetal abnormality affecting management of mother
 Pregnancy Complications 0.954 0.923 – 0.986 0.00564 4192 28851 exclusion phecode
656 Other perinatal conditions of fetus or newborn Pregnancy Complications 0.889 0.729 – 1.08 0.245 105 1051 exclusion phecode
661 Fetal distress and abnormal forces of labor Pregnancy Complications 0.914 0.874 – 0.956 8.34e-05 2210 18007 exclusion phecode
663
Umbilical cord complications during labor and
Umbilical cord complications during labor and delivery
 Pregnancy Complications 0.964 0.88 – 1.06 0.434 517 5194 exclusion phecode
665 Obstetrical/birth trauma Pregnancy Complications 0.926 0.898 – 0.955 7.72e-07 5235 28815 exclusion phecode
669 Complications of labor and delivery NEC Pregnancy Complications 0.933 0.895 – 0.974 0.00133 2502 20734 exclusion phecode
671
Venous/cerebrovascular complications embolism
Venous/cerebrovascular complications embolism in pregnancy and the puerperium
 Pregnancy Complications 1.06 0.898 – 1.25 0.493 158 1586 exclusion phecode
674 Other complications of the puerperium NEC Pregnancy Complications 1.12 0.985 – 1.28 0.0836 251 2547 exclusion phecode
676
Other disorders of the breast associated with
Other disorders of the breast associated with childbirth and disorders of lactation
 Pregnancy Complications 1.02 0.783 – 1.32 0.907 63 609 exclusion phecode
679 Complications of in utero procedures Dermatologic 0.752 0.569 – 0.995 0.0457 51 514 exclusion phecode
681 Superficial cellulitis and abscess Dermatologic 1.12 1.09 – 1.15 9.79e-18 6104 67994 exclusion phecode
681.1 Cellulitis and abscess of fingers/toes Dermatologic 1.1 1 – 1.21 0.0403 473 5322 exclusion phecode
681.2 Cellulitis and abscess of face/neck Dermatologic 1.14 1.04 – 1.25 0.00686 474 4941 exclusion phecode
681.3 Cellulitis and abscess of arm/hand Dermatologic 1.13 1.09 – 1.16 7.32e-15 4576 51689 exclusion phecode
681.5 Cellulitis and abscess of leg, except foot Dermatologic 1.13 1.1 – 1.16 3.36e-15 4581 51745 exclusion phecode
681.6 Cellulitis and abscess of foot, toe Dermatologic 1.13 1.1 – 1.16 4.18e-15 4541 51336 exclusion phecode
681.7 Cellulitis and abscess of trunk Dermatologic 1.1 1.01 – 1.21 0.0357 524 5692 exclusion phecode
686
Other local infections of skin and subcutaneous
Other local infections of skin and subcutaneous tissue
 Dermatologic 1.16 1.09 – 1.23 2.91e-06 1124 12646 exclusion phecode
686.1 Carbuncle and furuncle Dermatologic 1.14 1.09 – 1.19 5.78e-08 1948 21676 exclusion phecode
686.3 Pilonidal cyst Dermatologic 1.05 0.956 – 1.15 0.324 524 5552 exclusion phecode
686.4 Pyogenic granuloma Dermatologic 1.1 0.982 – 1.23 0.101 328 3429 exclusion phecode
687 Symptoms affecting skin Dermatologic 1.02 0.933 – 1.12 0.609 498 5216 exclusion phecode
687.1 Rash and other nonspecific skin eruption Dermatologic 1.05 1 – 1.1 0.0324 1945 20296 exclusion phecode
687.2 Localized superficial swelling, mass, or lump Dermatologic 1.06 0.936 – 1.2 0.351 264 2692 exclusion phecode
687.3 Changes in skin texture Dermatologic 0.876 0.713 – 1.08 0.208 103 1007 exclusion phecode
687.4 Disturbance of skin sensation Dermatologic 1.13 1.08 – 1.17 3.17e-09 2637 27337 exclusion phecode
689 Disorder of skin and subcutaneous tissue NOS Dermatologic 1.04 1.01 – 1.07 0.00569 5340 54233 exclusion phecode
690 Erythematosquamous dermatosis Dermatologic 1.01 0.78 – 1.3 0.959 63 652 exclusion phecode
690.1 Seborrheic dermatitis Dermatologic 1.04 0.783 – 1.37 0.799 46 494 exclusion phecode
691 Congenital anomalies of skin Dermatologic 1.06 0.875 – 1.27 0.568 112 1120 exclusion phecode
694 Dyschromia and Vitiligo Dermatologic 1.03 0.967 – 1.11 0.323 924 9323 exclusion phecode
694.1 Vitiligo Dermatologic 1.21 0.921 – 1.58 0.172 52 567 exclusion phecode
694.2 Other dyschromia Dermatologic 0.985 0.913 – 1.06 0.702 748 7415 exclusion phecode
694.3 Vascular disorders of skin Dermatologic 1.26 1.02 – 1.54 0.0287 99 1104 exclusion phecode
695 Erythematous conditions Dermatologic 1.07 1.02 – 1.12 0.00356 2170 22502 exclusion phecode
695.1 Toxic erythema Dermatologic 1.21 0.988 – 1.47 0.065 102 1042 exclusion phecode
695.2 Bullous dermatoses Dermatologic 1.09 0.907 – 1.31 0.362 121 1271 exclusion phecode
695.21 Dermatitis herpetiformis Dermatologic 1.23 0.928 – 1.62 0.151 51 526 exclusion phecode
695.22 Pemphigus and pemphigoid Dermatologic 0.964 0.757 – 1.23 0.766 64 682 exclusion phecode
695.3 Rosacea Dermatologic 1.04 0.926 – 1.18 0.485 283 2885 exclusion phecode
695.4 Lupus (localized and systemic) Dermatologic 1.01 0.909 – 1.12 0.884 391 3938 exclusion phecode
695.41 Cutaneous lupus erythematosus Dermatologic 0.905 0.756 – 1.08 0.273 124 1232 exclusion phecode
695.42 Systemic lupus erythematosus Dermatologic 1.03 0.925 – 1.16 0.553 323 3265 exclusion phecode
695.7 Prurigo and Lichen Dermatologic 1.09 1.01 – 1.18 0.0275 706 7357 exclusion phecode
695.8 Other specified erythematous conditions Dermatologic 1.08 0.941 – 1.25 0.267 210 2244 exclusion phecode
695.81 Erythema nodosum Dermatologic 1.02 0.803 – 1.29 0.876 71 730 exclusion phecode
695.9 Unspecified erythematous condition Dermatologic 1.04 0.939 – 1.15 0.45 417 4368 exclusion phecode
696 Psoriasis and related disorders Dermatologic 1.15 1.1 – 1.21 1.34e-09 1999 21181 exclusion phecode
696.4 Psoriasis Dermatologic 1.16 1.11 – 1.22 3.55e-10 1949 20688 exclusion phecode
696.41 Psoriasis vulgaris Dermatologic 1.18 1.12 – 1.25 9.6e-10 1482 15771 exclusion phecode
696.42 Psoriatic arthropathy Dermatologic 1.09 1 – 1.18 0.051 627 6658 exclusion phecode
697 Sarcoidosis Dermatologic 1.1 1.01 – 1.21 0.0368 487 5093 exclusion phecode
698 Pruritus and related conditions Dermatologic 1.13 1.05 – 1.22 0.00138 713 7402 exclusion phecode
700 Corns and callosities Dermatologic 1.01 0.897 – 1.15 0.828 268 2749 exclusion phecode
701
Other hypertrophic and atrophic conditions of
Other hypertrophic and atrophic conditions of skin
 Dermatologic 1.06 1.03 – 1.1 0.000105 4339 44148 exclusion phecode
701.1 Keratoderma, acquired Dermatologic 1.1 0.874 – 1.39 0.409 81 797 exclusion phecode
701.2 Scar conditions and fibrosis of skin Dermatologic 1.06 1.01 – 1.11 0.00913 2223 22237 exclusion phecode
701.3 Circumscribed scleroderma Dermatologic 0.977 0.734 – 1.3 0.874 54 587 exclusion phecode
701.4 Keloid scar Dermatologic 1.05 0.909 – 1.21 0.504 202 2074 exclusion phecode
701.5 Abnormal granulation tissue Dermatologic 1.04 0.945 – 1.15 0.402 422 4348 exclusion phecode
701.6 Acquired acanthosis nigricans Dermatologic 1.09 0.884 – 1.35 0.413 92 974 exclusion phecode
702
Degenerative skin conditions and other
Degenerative skin conditions and other dermatoses
 Dermatologic 1.01 0.978 – 1.04 0.645 5152 51237 exclusion phecode
702.1 Actinic keratosis Dermatologic 0.993 0.953 – 1.04 0.746 2428 24225 exclusion phecode
702.2 Seborrheic keratosis Dermatologic 1.03 0.989 – 1.07 0.161 2921 28890 exclusion phecode
703 Diseases of nail, NOS Dermatologic 1.04 0.93 – 1.17 0.466 320 3332 exclusion phecode
703.1 Ingrowing nail Dermatologic 1.05 0.98 – 1.13 0.16 838 9124 exclusion phecode
704 Diseases of hair and hair follicles Dermatologic 1.08 1.05 – 1.12 5.19e-08 4979 49801 exclusion phecode
704.1 Alopecia Dermatologic 1.25 1.04 – 1.51 0.0158 117 1225 exclusion phecode
704.8
Other specified diseases of hair and hair
Other specified diseases of hair and hair follicles
 Dermatologic 1.17 0.913 – 1.49 0.218 74 717 exclusion phecode
705 Disorders of sweat glands Dermatologic 1.13 0.983 – 1.31 0.0835 201 2187 exclusion phecode
705.3 Hidradenitis Dermatologic 1.23 1.05 – 1.44 0.011 164 1796 exclusion phecode
705.8 Hyperhidrosis Dermatologic 1.1 1 – 1.2 0.0386 540 5540 exclusion phecode
706 Diseases of sebaceous glands Dermatologic 1.06 1.04 – 1.09 3.77e-07 7841 78625 exclusion phecode
706.1 Acne Dermatologic 1.07 0.839 – 1.35 0.605 73 733 exclusion phecode
706.2 Sebaceous cyst Dermatologic 1.06 1.04 – 1.08 4.3e-07 8282 83006 exclusion phecode
707 Chronic ulcer of skin Dermatologic 1.24 1.17 – 1.31 2.22e-14 1374 18299 exclusion phecode
707.1 Decubitus ulcer Dermatologic 1.16 1.07 – 1.25 0.000149 727 8446 exclusion phecode
709 Diffuse diseases of connective tissue Dermatologic 1.09 1.05 – 1.13 3.47e-06 3018 32437 exclusion phecode
709.2 Sicca syndrome Dermatologic 1.1 1 – 1.21 0.044 479 4856 exclusion phecode
709.3 Systemic sclerosis Dermatologic 1.02 0.863 – 1.2 0.852 163 1671 exclusion phecode
709.6
Other specified diffuse diseases of connective
Other specified diffuse diseases of connective tissue
 Dermatologic 0.992 0.762 – 1.29 0.954 61 614 exclusion phecode
709.7 Unspecified diffuse connective tissue disease Dermatologic 1.1 1.05 – 1.15 1.16e-05 2346 25597 exclusion phecode
710
Osteomyelitis, periostitis, and other
Osteomyelitis, periostitis, and other infections involving bone
 Musculoskeletal 1.22 1.1 – 1.34 0.000102 427 5631 exclusion phecode
710.1 Osteomyelitis Musculoskeletal 1.26 1.13 – 1.4 1.43e-05 387 5206 exclusion phecode
710.12 Chronic osteomyelitis Musculoskeletal 1.17 0.992 – 1.38 0.0616 154 1841 exclusion phecode
710.19 Unspecified osteomyelitis Musculoskeletal 1.27 1.12 – 1.45 0.000196 253 3710 exclusion phecode
711 Arthropathy associated with infections Musculoskeletal 1.15 1.04 – 1.28 0.00916 368 3990 exclusion phecode
711.1 Pyogenic arthritis Musculoskeletal 1.19 1.06 – 1.34 0.00465 282 3105 exclusion phecode
712 Infective connective tissue disorders Musculoskeletal 1.1 0.87 – 1.4 0.42 73 758 exclusion phecode
713
Arthropathy associated with other disorders
Arthropathy associated with other disorders classified elsewhere
 Musculoskeletal 0.952 0.766 – 1.18 0.659 81 1415 exclusion phecode
713.5
Arthropathy associated with neurological
Arthropathy associated with neurological disorders
 Musculoskeletal 1.66 0.906 – 3.05 0.1 6 620 exclusion phecode
714
Rheumatoid arthritis and other inflammatory
Rheumatoid arthritis and other inflammatory polyarthropathies
 Musculoskeletal 1.15 1.12 – 1.19 1.3e-18 4357 45792 exclusion phecode
714.1 Rheumatoid arthritis Musculoskeletal 1.15 1.11 – 1.18 3.14e-16 3953 41437 exclusion phecode
715 Other inflammatory spondylopathies Musculoskeletal 1.17 1.1 – 1.23 2.04e-08 1511 15657 exclusion phecode
715.1 Sacroiliitis NEC Musculoskeletal 1.12 0.916 – 1.38 0.265 106 1087 exclusion phecode
715.2 Ankylosing spondylitis Musculoskeletal 1.08 0.993 – 1.18 0.0729 567 5804 exclusion phecode
716 Other arthropathies Musculoskeletal 1.15 1.14 – 1.16 2.53e-130 34189 251534 exclusion phecode
716.1 Unspecified polyarthropathy or polyarthritis Musculoskeletal 1.17 1.13 – 1.22 9.31e-18 3136 33100 exclusion phecode
716.2 Unspecified monoarthritis Musculoskeletal 1.16 1.14 – 1.18 1.01e-66 14255 146413 exclusion phecode
716.9 Arthropathy NOS Musculoskeletal 1.15 1.14 – 1.17 1.56e-127 32782 248570 exclusion phecode
717 Polymyalgia Rheumatica Musculoskeletal 1.17 1.1 – 1.25 5.3e-07 1056 10755 exclusion phecode
720 Spinal stenosis Musculoskeletal 1.16 1.12 – 1.2 1.6e-16 3327 34811 exclusion phecode
721 Spondylosis and allied disorders Musculoskeletal 1.15 1.13 – 1.18 1.88e-30 7082 73821 exclusion phecode
721.1 Spondylosis without myelopathy Musculoskeletal 1.16 1.13 – 1.2 7.57e-23 4568 47580 exclusion phecode
721.2 Spondylosis with myelopathy Musculoskeletal 1.24 1.05 – 1.46 0.0102 162 1779 exclusion phecode
721.8 Other allied disorders of spine Musculoskeletal 1.11 0.988 – 1.24 0.0806 322 3334 exclusion phecode
722 Intervertebral disc disorders Musculoskeletal 1.13 1.11 – 1.16 4.33e-27 8258 85149 exclusion phecode
722.1 Displacement of intervertebral disc Musculoskeletal 1.07 0.975 – 1.18 0.147 469 4833 exclusion phecode
722.6 Degeneration of intervertebral disc Musculoskeletal 1.15 1.1 – 1.2 1.55e-11 2598 26876 exclusion phecode
722.8 Postlaminectomy syndrome Musculoskeletal 1.35 1.04 – 1.74 0.0229 65 636 exclusion phecode
722.9 Other and unspecified disc disorder Musculoskeletal 1.12 1.09 – 1.16 2.1e-12 4073 41781 exclusion phecode
723 Other disorders of cervical region Musculoskeletal 1.18 1.08 – 1.3 0.000554 475 4864 exclusion phecode
723.1 Torticollis Musculoskeletal 1.25 1.02 – 1.53 0.0296 100 1017 exclusion phecode
724 Other and unspecified disorders of back Musculoskeletal 1.12 1.06 – 1.17 6.75e-06 1902 19394 exclusion phecode
724.1 Disorders of sacrum Musculoskeletal 1.21 1.09 – 1.34 0.000311 383 3847 exclusion phecode
724.2 Disorders of coccyx Musculoskeletal 1.19 1.08 – 1.33 0.000801 386 3872 exclusion phecode
724.8 Other symptoms referable to back Musculoskeletal 1.39 1.06 – 1.83 0.0166 57 606 exclusion phecode
724.9 Other unspecified back disorders Musculoskeletal 1.08 1.02 – 1.14 0.00465 1490 15196 exclusion phecode
726 Peripheral enthesopathies and allied syndromes Musculoskeletal 1.12 1.1 – 1.14 1.2e-34 13398 138816 exclusion phecode
726.1 Enthesopathy Musculoskeletal 1.11 1.09 – 1.14 1.06e-21 8757 90645 exclusion phecode
726.2 Synoviopathy Musculoskeletal 1.27 1.12 – 1.42 9.27e-05 308 3177 exclusion phecode
726.3 Bursitis Musculoskeletal 1.09 1.01 – 1.18 0.0237 765 8075 exclusion phecode
727 Other disorders of synovium, tendon, and bursa Musculoskeletal 1.09 1.06 – 1.12 7.28e-12 6854 69603 exclusion phecode
727.1 Synovitis and tenosynovitis Musculoskeletal 1.1 1.05 – 1.14 8.3e-06 2522 26036 exclusion phecode
727.2 Bursitis disorders Musculoskeletal 1.14 0.923 – 1.41 0.224 92 978 exclusion phecode
727.4 Ganglion and cyst of synovium, tendon, and bursa Musculoskeletal 1.07 1.03 – 1.11 0.000371 2939 29661 exclusion phecode
727.5 Rupture of synovium Musculoskeletal 1.05 0.956 – 1.14 0.329 542 5507 exclusion phecode
727.6 Rupture of tendon, nontraumatic Musculoskeletal 1.15 1.02 – 1.28 0.0175 330 3313 exclusion phecode
727.7 Contracture of tendon (sheath) Musculoskeletal 1.07 0.896 – 1.27 0.472 136 1360 exclusion phecode
728 Disorders of muscle, ligament, and fascia Musculoskeletal 1.03 0.993 – 1.07 0.112 3324 34058 exclusion phecode
728.2 Laxity of ligament or hypermobility syndrome Musculoskeletal 1.09 0.981 – 1.21 0.11 395 3962 exclusion phecode
728.7 Fasciitis Musculoskeletal 1.03 0.998 – 1.07 0.0612 3444 35266 exclusion phecode
728.71
Contracture of palmar fascia [Dupuytren's
Contracture of palmar fascia [Dupuytren's disease]
 Musculoskeletal 1.02 0.988 – 1.06 0.191 3141 32186 exclusion phecode
729 Other disorders of soft tissues Musculoskeletal 1.18 1.15 – 1.22 4.03e-32 5430 57052 exclusion phecode
729.1 Rheumatism, unspecified and fibrositis Musculoskeletal 1.18 1.1 – 1.26 1.9e-06 906 9645 exclusion phecode
729.3 Panniculitis Musculoskeletal 1.1 0.888 – 1.35 0.395 93 966 exclusion phecode
731
Osteitis deformans and osteopathies associated
Osteitis deformans and osteopathies associated with other disorders classified elsewhere
 Musculoskeletal 1.17 1.03 – 1.33 0.0174 257 2633 exclusion phecode
731.1 Osteitis deformans [Paget's disease of bone] Musculoskeletal 1.16 1.02 – 1.32 0.0259 243 2487 exclusion phecode
732 Osteochondropathies Musculoskeletal 1.08 0.977 – 1.19 0.135 447 4441 exclusion phecode
732.1 Juvenile osteochondrosis Musculoskeletal 1.03 0.888 – 1.2 0.68 195 1952 exclusion phecode
732.7 Osteochondritis dissecans Musculoskeletal 0.944 0.714 – 1.25 0.687 57 541 exclusion phecode
733 Other disorders of bone and cartilage Musculoskeletal 1.06 1 – 1.11 0.0374 1668 16864 exclusion phecode
733.2 Cyst of bone Musculoskeletal 1.19 1.05 – 1.34 0.00466 299 2943 exclusion phecode
733.4 Aseptic necrosis of bone Musculoskeletal 1.01 0.92 – 1.11 0.855 499 5091 exclusion phecode
733.6 Costochondritis Musculoskeletal 1.33 1.1 – 1.6 0.00269 122 1218 exclusion phecode
733.8 Malunion and nonunion of fracture Musculoskeletal 1.06 1 – 1.13 0.0455 1154 11673 exclusion phecode
733.9 Chondromalacia Musculoskeletal 1.26 1.04 – 1.52 0.0172 114 1150 exclusion phecode
735 Acquired foot deformities Musculoskeletal 1.05 1.03 – 1.07 1.81e-05 9254 91386 exclusion phecode
735.1 Flat foot Musculoskeletal 1.06 0.913 – 1.24 0.428 185 1810 exclusion phecode
735.2 Acquired toe deformities Musculoskeletal 1.07 1.04 – 1.1 3.69e-06 4866 48115 exclusion phecode
735.21 Hammer toe (acquired) Musculoskeletal 1.07 1.02 – 1.12 0.00522 1850 18337 exclusion phecode
735.23 Hallux rigidus Musculoskeletal 1.08 1.03 – 1.14 0.0041 1498 14710 exclusion phecode
735.3 Hallux valgus (Bunion) Musculoskeletal 1.02 0.995 – 1.05 0.123 6437 63406 exclusion phecode
736 Other acquired deformities of limbs Musculoskeletal 1.07 1.01 – 1.12 0.015 1512 15264 exclusion phecode
736.2 Acquired deformities of finger Musculoskeletal 0.984 0.866 – 1.12 0.811 239 2337 exclusion phecode
737 Curvature of spine Musculoskeletal 1.03 0.97 – 1.1 0.308 1067 10715 exclusion phecode
737.3 Kyphoscoliosis and scoliosis Musculoskeletal 1.03 0.962 – 1.09 0.434 1008 10064 exclusion phecode
738 Other acquired musculoskeletal deformity Musculoskeletal 1.1 1.05 – 1.16 7.64e-05 1753 18065 exclusion phecode
738.4 Acquired spondylolisthesis Musculoskeletal 1.12 1.06 – 1.18 5.06e-05 1392 14362 exclusion phecode
739 Contracture of joint Musculoskeletal 1.06 0.961 – 1.17 0.245 454 4621 exclusion phecode
740 Osteoarthrosis Musculoskeletal 1.1 1.09 – 1.12 9.49e-50 25395 218276 exclusion phecode
740.1 Osteoarthritis; localized Musculoskeletal 1.09 1.07 – 1.11 3.41e-24 16122 159216 exclusion phecode
740.11 Osteoarthrosis, localized, primary Musculoskeletal 1.1 1.08 – 1.13 1.66e-17 8251 84140 exclusion phecode
740.12 Osteoarthrosis, localized, secondary Musculoskeletal 0.961 0.859 – 1.08 0.491 327 3292 exclusion phecode
740.2 Osteoarthrosis, generalized Musculoskeletal 1.14 1.05 – 1.24 0.00274 551 5605 exclusion phecode
740.9 Osteoarthrosis NOS Musculoskeletal 1.14 1.12 – 1.17 7.85e-41 11062 115758 exclusion phecode
741 Symptoms and disorders of the joints Musculoskeletal 1.12 1.08 – 1.16 8.72e-10 3265 33551 exclusion phecode
741.1 Ankylosis of joint Musculoskeletal 1.24 1.02 – 1.52 0.0352 96 953 exclusion phecode
741.2 Stiffness of joint Musculoskeletal 1.11 1.02 – 1.21 0.0215 569 5806 exclusion phecode
741.3 Difficulty in walking Musculoskeletal 1.03 0.857 – 1.24 0.754 126 1431 exclusion phecode
741.4 Joint effusions Musculoskeletal 1.13 1.06 – 1.19 4.58e-05 1283 13289 exclusion phecode
741.5 Hemarthrosis Musculoskeletal 1.12 0.914 – 1.37 0.276 101 1036 exclusion phecode
741.6 Villonodular synovitis Musculoskeletal 1.05 0.789 – 1.4 0.729 51 514 exclusion phecode
742 Derangement of joint, non-traumatic Musculoskeletal 1.12 1.07 – 1.16 4.23e-08 2680 27102 exclusion phecode
742.1 Loose body in joint Musculoskeletal 1.08 0.968 – 1.21 0.16 315 3159 exclusion phecode
742.2
Pathological, developmental or recurrent
Pathological, developmental or recurrent dislocation
 Musculoskeletal 1.22 0.979 – 1.51 0.0774 87 934 exclusion phecode
742.8 Articular cartilage disorder Musculoskeletal 1.12 1.02 – 1.23 0.0201 459 4762 exclusion phecode
742.9 Other derangement of joint Musculoskeletal 1.12 1.07 – 1.18 1.35e-06 1898 19016 exclusion phecode
743
Osteoporosis, osteopenia and pathological
Osteoporosis, osteopenia and pathological fracture
 Musculoskeletal 1.04 1.02 – 1.07 0.000891 7063 71598 exclusion phecode
743.1 Osteoporosis Musculoskeletal 1.04 1.01 – 1.07 0.00455 5975 60607 exclusion phecode
743.11 Osteoporosis NOS Musculoskeletal 1.04 1.01 – 1.07 0.00706 5187 52642 exclusion phecode
743.13 Other specified osteoporosis Musculoskeletal 1.15 1.04 – 1.26 0.00407 487 4960 exclusion phecode
743.2 Pathologic fracture Musculoskeletal 1.08 0.98 – 1.19 0.121 470 4849 exclusion phecode
743.9
Osteopenia or other disorder of bone and
Osteopenia or other disorder of bone and cartilage
 Musculoskeletal 1.03 0.956 – 1.11 0.438 771 7736 exclusion phecode
745 Pain in joint Musculoskeletal 1.14 1.11 – 1.17 3.34e-27 7314 75549 exclusion phecode
747 Cardiac and circulatory congenital anomalies Congenital Anomalies 1.12 1.08 – 1.17 4.68e-08 2444 26246 exclusion phecode
747.1 Cardiac congenital anomalies Congenital Anomalies 1.13 1.08 – 1.17 5.68e-08 2282 24611 exclusion phecode
747.11 Cardiac shunt/ heart septal defect Congenital Anomalies 0.934 0.854 – 1.02 0.131 552 5570 exclusion phecode
747.12 Valvular heart disease/ heart chambers Congenital Anomalies 1.05 0.913 – 1.21 0.496 222 2232 exclusion phecode
747.13 Congenital anomalies of great vessels Congenital Anomalies 1.2 1.14 – 1.26 8.22e-12 1517 16840 exclusion phecode
747.2
Congenital anomalies of peripheral vascular
Congenital anomalies of peripheral vascular system
 Congenital Anomalies 1.07 0.902 – 1.26 0.452 154 1589 exclusion phecode
748 Anomalies of respiratory system, congenital Congenital Anomalies 1.12 0.834 – 1.49 0.462 49 479 exclusion phecode
749 Congenital anomalies of face and neck Congenital Anomalies 0.968 0.857 – 1.09 0.603 282 2892 exclusion phecode
750 Digestive congenital anomalies Congenital Anomalies 0.968 0.892 – 1.05 0.434 646 6422 exclusion phecode
750.1 Upper gastrointestinal congenital anomalies Congenital Anomalies 0.943 0.838 – 1.06 0.324 304 3046 exclusion phecode
750.13 Congenital anomalies of mouth/tongue Congenital Anomalies 0.885 0.759 – 1.03 0.117 182 1772 exclusion phecode
750.2 Lower gastrointestinal congenital anomalies Congenital Anomalies 0.994 0.888 – 1.11 0.911 338 3363 exclusion phecode
750.21 Congenital anomalies of intestine Congenital Anomalies 0.92 0.801 – 1.06 0.234 217 2115 exclusion phecode
750.22
Congenital anomaly of gallbladder, bile ducts
Congenital anomaly of gallbladder, bile ducts, liver, pancreas
 Congenital Anomalies 1.11 0.905 – 1.36 0.32 110 1119 exclusion phecode
751 Genitourinary congenital anomalies Congenital Anomalies 0.994 0.942 – 1.05 0.829 1418 14452 exclusion phecode
751.1 Congenital anomalies of genital organs Congenital Anomalies 0.99 0.914 – 1.07 0.815 661 6602 exclusion phecode
751.11 Congenital anomalies of female genital organs Congenital Anomalies 1 0.906 – 1.1 0.996 442 4394 exclusion phecode
751.12 Congenital anomalies of male genital organs Congenital Anomalies 0.95 0.824 – 1.1 0.484 202 2042 exclusion phecode
751.2 Congenital anomalies of urinary system Congenital Anomalies 1.02 0.949 – 1.1 0.573 759 7863 exclusion phecode
751.21 Cystic kidney disease Congenital Anomalies 0.997 0.899 – 1.1 0.951 380 3981 exclusion phecode
751.22 Other specified congenital anomalies of kidney Congenital Anomalies 1.03 0.913 – 1.15 0.661 301 3141 exclusion phecode
752 Nervous system congenital anomalies Congenital Anomalies 1.11 0.992 – 1.25 0.0677 310 3151 exclusion phecode
752.1 Neural tube defects Congenital Anomalies 1.09 0.955 – 1.24 0.203 242 2440 exclusion phecode
752.11 Spina bifida Congenital Anomalies 1.06 0.918 – 1.22 0.432 201 2013 exclusion phecode
752.2
Other specified congenital anomalies of nervous
Other specified congenital anomalies of nervous system
 Congenital Anomalies 1.17 0.923 – 1.49 0.194 71 739 exclusion phecode
753 Congenital anomalies of the eye Congenital Anomalies 1.32 1.09 – 1.6 0.00458 120 1197 exclusion phecode
753.1 Congenital cataract and lens anomalies Congenital Anomalies 1.33 1.03 – 1.71 0.0265 72 716 exclusion phecode
754 Congenital musculoskeletal deformities of spine Congenital Anomalies 1.16 0.952 – 1.42 0.138 103 1041 exclusion phecode
755 Congenital anomalies of limbs Congenital Anomalies 1.17 1.06 – 1.3 0.00225 408 4087 exclusion phecode
755.1 Congenital deformities of feet Congenital Anomalies 1.12 0.972 – 1.3 0.116 193 1984 exclusion phecode
755.6
Other congenital anomalies of lower limb
Other congenital anomalies of lower limb, including pelvic girdle
 Congenital Anomalies 1.15 0.974 – 1.35 0.0992 159 1556 exclusion phecode
755.61 Congenital hip dysplasia and deformity Congenital Anomalies 1.16 0.948 – 1.41 0.152 106 1033 exclusion phecode
756 Other congenital musculoskeletal anomalies Congenital Anomalies 1.05 0.966 – 1.15 0.233 553 5548 exclusion phecode
756.3
Congenital anomalies of muscle, tendon, fascia
Congenital anomalies of muscle, tendon, fascia, and connective tissue
 Congenital Anomalies 1.19 0.939 – 1.51 0.15 78 768 exclusion phecode
756.5 Congenital osteodystrophies Congenital Anomalies 1.05 0.952 – 1.17 0.312 408 4121 exclusion phecode
758 Chromosomal anomalies and genetic disorders Congenital Anomalies 0.942 0.789 – 1.13 0.51 142 1619 exclusion phecode
758.1 Chromosomal anomalies Congenital Anomalies 0.997 0.763 – 1.3 0.983 57 793 exclusion phecode
759 Other and unspecified congenital anomalies Congenital Anomalies 1.06 0.917 – 1.21 0.454 204 2055 exclusion phecode
759.1 Anomalies of endocrine glands, congenital Congenital Anomalies 1.11 0.903 – 1.37 0.317 91 912 exclusion phecode
760 Back pain Symptoms 1.13 1.11 – 1.15 2.41e-31 10118 105492 exclusion phecode
761 Cervicalgia Symptoms 1.12 1.06 – 1.17 2.31e-05 1629 16951 exclusion phecode
764 Sciatica Symptoms 1.15 1.1 – 1.2 4.64e-10 2185 22486 exclusion phecode
766 Neuralgia, neuritis, and radiculitis NOS Symptoms 1.11 1.04 – 1.18 0.00135 1070 11115 exclusion phecode
770 Myalgia and myositis unspecified Symptoms 1.1 1.01 – 1.2 0.029 569 5994 exclusion phecode
771 Musculoskeletal symptoms referable to limbs Symptoms 1.16 1.07 – 1.25 0.000121 778 8187 exclusion phecode
771.1 Swelling of limb Symptoms 1.18 1.15 – 1.22 2.31e-25 4161 43631 exclusion phecode
772 Symptoms of the muscles Symptoms 1.06 0.973 – 1.15 0.182 584 6195 exclusion phecode
773 Pain in limb Symptoms 1.12 1.09 – 1.15 1.1e-16 5628 58848 exclusion phecode
780 Hypothermia/Chills Symptoms 1.07 0.902 – 1.27 0.444 140 1635 exclusion phecode
781
Symptoms involving nervous and musculoskeletal
Symptoms involving nervous and musculoskeletal systems
 Symptoms 1.14 1.08 – 1.2 6.23e-07 1659 17686 exclusion phecode
782.3 Edema Symptoms 1.16 1.09 – 1.22 2.11e-07 1365 15365 exclusion phecode
782.6 Pallor and flushing Symptoms 1.09 0.929 – 1.28 0.284 153 1650 exclusion phecode
783 Fever of unknown origin Symptoms 1.09 1.05 – 1.13 1.49e-06 3539 36765 exclusion phecode
785 Abdominal pain Symptoms 1.08 1.07 – 1.1 5.28e-48 37406 286103 exclusion phecode
788 Syncope and collapse Symptoms 1.08 1.06 – 1.11 4.62e-12 8117 85154 exclusion phecode
789 Nausea and vomiting Symptoms 1.12 1.1 – 1.14 2.91e-29 10410 109905 exclusion phecode
790 Nonspecific findings on examination of blood Symptoms 1.12 0.944 – 1.34 0.189 141 1405 exclusion phecode
790.1 Elevated sedimentation rate Symptoms 1.26 1 – 1.57 0.0468 76 782 exclusion phecode
790.6 Other abnormal blood chemistry Symptoms 1.08 1.05 – 1.11 5.93e-09 5705 58767 exclusion phecode
791 Gangrene Symptoms 1.27 1.14 – 1.4 5.35e-06 382 5152 exclusion phecode
792
Abnormal Papanicolaou smear of cervix and
Abnormal Papanicolaou smear of cervix and cervical HPV
 Symptoms 0.906 0.728 – 1.13 0.375 95 925 exclusion phecode
793
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of musculoskeletal system
 Symptoms 0.89 0.739 – 1.07 0.217 116 1249 exclusion phecode
793.2
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of other intrathoracic organs (echocardiogram, etc)
 Symptoms 1.1 1.01 – 1.2 0.0322 520 5317 exclusion phecode
794
Abnormal results of other function studies
Abnormal results of other function studies (bladder, pancreas, placenta, spleen, etc)
 Symptoms 0.974 0.803 – 1.18 0.788 113 1158 exclusion phecode
797 Shock Symptoms 1.02 0.847 – 1.24 0.813 126 1455 exclusion phecode
797.1 Cardiogenic shock Symptoms 1.03 0.808 – 1.31 0.812 75 944 exclusion phecode
798 Malaise and fatigue Symptoms 1.14 1.1 – 1.18 9.97e-12 3074 32254 exclusion phecode
798.1 Chronic fatigue syndrome Symptoms 1.09 0.998 – 1.19 0.0555 548 5681 exclusion phecode
800 Fracture of lower limb Injuries & Poisonings 1.04 1.01 – 1.07 0.00268 6478 66496 exclusion phecode
800.1 Fracture of neck of femur Injuries & Poisonings 1 0.951 – 1.05 0.987 1668 17025 exclusion phecode
800.2 Fracture of unspecified part of femur Injuries & Poisonings 1.05 0.887 – 1.23 0.596 151 1587 exclusion phecode
800.3 Fracture of tibia and fibula Injuries & Poisonings 1.03 0.985 – 1.08 0.186 2001 20477 exclusion phecode
800.4 Fracture of patella Injuries & Poisonings 1.03 0.958 – 1.12 0.391 709 7196 exclusion phecode
801 Fracture of ankle and foot Injuries & Poisonings 1.08 1.03 – 1.13 0.00144 2048 20884 exclusion phecode
801.1 Fracture of foot Injuries & Poisonings 1.04 0.991 – 1.09 0.107 1708 17374 exclusion phecode
802 Fracture of pelvis Injuries & Poisonings 0.978 0.903 – 1.06 0.592 675 6757 exclusion phecode
803 Fracture of upper limb Injuries & Poisonings 0.992 0.969 – 1.02 0.486 7835 78638 exclusion phecode
803.1 Fracture of humerus Injuries & Poisonings 1.05 0.997 – 1.11 0.0649 1532 15970 exclusion phecode
803.2 Fracture of radius and ulna Injuries & Poisonings 0.965 0.937 – 0.994 0.0176 5004 49646 exclusion phecode
803.3 Fracture of clavicle or scapula Injuries & Poisonings 1.03 0.98 – 1.09 0.221 1422 14317 exclusion phecode
804 Fracture of hand or wrist Injuries & Poisonings 1 0.966 – 1.04 0.91 3172 31635 exclusion phecode
805
Fracture of vertebral column without mention of
Fracture of vertebral column without mention of spinal cord injury
 Injuries & Poisonings 1.05 0.992 – 1.12 0.0887 1253 12743 exclusion phecode
807 Fracture of ribs Injuries & Poisonings 1.02 0.949 – 1.1 0.542 723 7285 exclusion phecode
809 Fracture of unspecified bones Injuries & Poisonings 1 0.946 – 1.07 0.886 1195 12215 exclusion phecode
817 Concussion Injuries & Poisonings 0.873 0.762 – 1 0.0498 228 2295 exclusion phecode
818 Intracranial hemorrhage (injury) Injuries & Poisonings 1.1 0.999 – 1.21 0.052 469 4844 exclusion phecode
819
Skull and face fracture and other intercranial
Skull and face fracture and other intercranial injury
 Injuries & Poisonings 1.04 0.996 – 1.08 0.0745 2780 27999 exclusion phecode
823 Torus fracture Injuries & Poisonings 1 0.951 – 1.06 0.932 1553 15891 exclusion phecode
830 Dislocation Injuries & Poisonings 1.04 0.994 – 1.09 0.0854 1981 19750 exclusion phecode
835 Internal derangement of knee Injuries & Poisonings 1.09 1.07 – 1.11 1.92e-23 14368 143917 exclusion phecode
836 Traumatic arthropathy Injuries & Poisonings 1.16 1.06 – 1.27 0.00143 489 4961 exclusion phecode
840 Sprains and strains Injuries & Poisonings 0.955 0.867 – 1.05 0.347 455 4463 exclusion phecode
850 Hemorrhage or hematoma complicating a procedure Injuries & Poisonings 1.11 1.07 – 1.14 2.17e-11 4831 49685 exclusion phecode
851
Complications of transplants and reattached
Complications of transplants and reattached limbs
 Injuries & Poisonings 1.22 1.03 – 1.45 0.0232 142 1484 exclusion phecode
853 Complication of colostomy or enterostomy Injuries & Poisonings 1.18 1.07 – 1.3 0.000567 445 4715 exclusion phecode
854
Complications of cardiac/vascular device
Complications of cardiac/vascular device, implant, and graft
 Injuries & Poisonings 1.13 1.07 – 1.19 6.05e-06 1490 16959 exclusion phecode
857
Mechanical complication of unspecified
Mechanical complication of unspecified genitourinary device, implant, and graft
 Injuries & Poisonings 1.08 1.02 – 1.15 0.0144 1115 11686 exclusion phecode
858 Complication of internal orthopedic device Injuries & Poisonings 1.13 1.09 – 1.17 5.26e-10 2928 29749 exclusion phecode
859
Complication due to other implant and internal
Complication due to other implant and internal device
 Injuries & Poisonings 1.13 1.09 – 1.17 3.28e-10 2992 30725 exclusion phecode
860 Bone marrow or stem cell transplant Neoplasms 1.14 0.87 – 1.48 0.347 63 644 exclusion phecode
870 Open wounds of head; neck; and trunk Injuries & Poisonings 1.05 1.01 – 1.09 0.00827 3232 32981 exclusion phecode
870.1 Open wound or laceration of eye or eyelid Injuries & Poisonings 1.07 0.94 – 1.21 0.31 253 2529 exclusion phecode
870.2 Open wound of ear Injuries & Poisonings 0.899 0.77 – 1.05 0.18 179 1833 exclusion phecode
870.3 Other open wound of head and face Injuries & Poisonings 1.05 1.01 – 1.09 0.0196 2688 27359 exclusion phecode
870.4 Open wound of nose and sinus Injuries & Poisonings 1.02 0.887 – 1.17 0.771 205 2060 exclusion phecode
870.6 Open wound of neck Injuries & Poisonings 1.05 0.814 – 1.36 0.706 62 648 exclusion phecode
871 Open wounds of extremities Injuries & Poisonings 1.04 1.01 – 1.08 0.0177 3818 38378 exclusion phecode
871.1 Open wound of hand except finger(s) Injuries & Poisonings 1.33 0.995 – 1.79 0.0542 48 492 exclusion phecode
871.2 Open wound of finger(s) Injuries & Poisonings 1.03 0.831 – 1.28 0.774 85 831 exclusion phecode
871.3 Open wound of foot except toe(s) alone Injuries & Poisonings 0.996 0.846 – 1.17 0.962 152 1697 exclusion phecode
872 Traumatic amputation Injuries & Poisonings 0.994 0.902 – 1.09 0.896 445 4452 exclusion phecode
873 Broken tooth Injuries & Poisonings 1.06 0.916 – 1.22 0.452 206 2153 exclusion phecode
874 Complication of amputation stump Injuries & Poisonings 1.03 0.851 – 1.24 0.781 118 1601 exclusion phecode
905
Late effects of musculoskeletal and connective
Late effects of musculoskeletal and connective tissue injuries
 Injuries & Poisonings 1.18 0.999 – 1.4 0.0514 147 1473 exclusion phecode
907 Injuries to the nervous system Injuries & Poisonings 1.16 1.1 – 1.23 4.89e-07 1248 12415 exclusion phecode
915 Superficial injury without mention of infection Injuries & Poisonings 1.1 1.06 – 1.14 1.82e-08 3823 40191 exclusion phecode
916 Contusion Injuries & Poisonings 1.08 1.03 – 1.15 0.00479 1326 13662 exclusion phecode
930 Allergic reaction to food Injuries & Poisonings 1.26 1.07 – 1.47 0.0045 166 1721 exclusion phecode
938 Dermatitis due to solar radiation Injuries & Poisonings 1.09 0.976 – 1.21 0.127 363 3639 exclusion phecode
938.2 Chronic dermatitis due to solar radiation Injuries & Poisonings 1.12 0.981 – 1.29 0.0921 236 2354 exclusion phecode
939
Atopic/contact dermatitis due to other or
Atopic/contact dermatitis due to other or unspecified
 Dermatologic 1.07 1.02 – 1.12 0.00364 1938 19711 exclusion phecode
941 Adverse reaction to serum or vaccine Injuries & Poisonings 1.07 0.93 – 1.24 0.333 204 2116 exclusion phecode
942 Infusion and transfusion reaction Injuries & Poisonings 1.2 0.965 – 1.48 0.102 98 986 exclusion phecode
946 Anaphylactic shock NOS Injuries & Poisonings 1.22 1.11 – 1.33 2.69e-05 487 5239 exclusion phecode
947 Urticaria Injuries & Poisonings 1.24 1.11 – 1.39 0.00012 348 3538 exclusion phecode
949 Allergies, other Injuries & Poisonings 1.11 0.997 – 1.23 0.0572 367 3816 exclusion phecode
952
Spinal cord injury without evidence of spinal
Spinal cord injury without evidence of spinal bone injury
 Injuries & Poisonings 1.05 0.947 – 1.17 0.343 386 3967 exclusion phecode
957 Injury to other and unspecified nerves Injuries & Poisonings 1.41 1.24 – 1.6 1.43e-07 248 2544 exclusion phecode
958
Certain early complications of trauma or
Certain early complications of trauma or procedure
 Injuries & Poisonings 1.09 0.985 – 1.2 0.0987 447 4626 exclusion phecode
958.1 Postoperative shock Injuries & Poisonings 1.2 0.884 – 1.63 0.244 43 509 exclusion phecode
958.2 Traumatic and surgical subcutaneous emphysema Injuries & Poisonings 1 0.785 – 1.28 0.975 70 685 exclusion phecode
960 Poisoning by antibiotics Injuries & Poisonings 1.12 1.1 – 1.13 1.99e-41 16634 172453 exclusion phecode
960.2 Allergy/adverse effect of penicillin Injuries & Poisonings 1.11 1.09 – 1.13 6.16e-35 14535 150937 exclusion phecode
961 Poisoning by other anti-infectives Injuries & Poisonings 1.17 1.05 – 1.3 0.00428 380 3984 exclusion phecode
961.1 Poisoning/allergy of sulfonamides Injuries & Poisonings 1.1 1.02 – 1.18 0.0134 806 8332 exclusion phecode
962 Poisoning by hormones and synthetic substitutes Injuries & Poisonings 1.41 1.26 – 1.58 4.58e-09 315 3517 exclusion phecode
962.3
Hormones and synthetic substitutes causing
Hormones and synthetic substitutes causing adverse effects in therapeutic use
 Injuries & Poisonings 1.42 1.26 – 1.59 3.13e-09 307 3449 exclusion phecode
963 Poisoning by primarily systemic agents Injuries & Poisonings 1.17 1.02 – 1.35 0.029 210 2118 exclusion phecode
964
Poisoning by agents primarily affecting blood
Poisoning by agents primarily affecting blood constituents
 Injuries & Poisonings 1.16 1.02 – 1.32 0.0259 240 2617 exclusion phecode
964.1 Anticoagulants causing adverse effects Injuries & Poisonings 1.13 0.986 – 1.28 0.0807 234 2561 exclusion phecode
965
Poisoning by analgesics, antipyretics, and
Poisoning by analgesics, antipyretics, and antirheumatics
 Injuries & Poisonings 1.14 1.11 – 1.17 5.48e-20 5530 57958 exclusion phecode
965.1
Opiates and related narcotics causing adverse
Opiates and related narcotics causing adverse effects in therapeutic use
 Injuries & Poisonings 1.16 1.08 – 1.23 1.04e-05 1038 10963 exclusion phecode
965.2
Antirheumatics causing adverse effects in
Antirheumatics causing adverse effects in therapeutic use
 Injuries & Poisonings 1.21 1.09 – 1.33 0.000185 433 4576 exclusion phecode
965.3
Salicylates causing adverse effects in
Salicylates causing adverse effects in therapeutic use
 Injuries & Poisonings 1.22 1.09 – 1.36 0.000523 357 3825 exclusion phecode
966
Poisoning by anticonvulsants and
Poisoning by anticonvulsants and anti-Parkinsonism drugs
 Injuries & Poisonings 1.18 1.07 – 1.3 0.00066 467 4894 exclusion phecode
967
Adverse effects of sedatives or other central
Adverse effects of sedatives or other central nervous system depressants and anesthetics
 Injuries & Poisonings 1.13 1.03 – 1.23 0.00744 542 5559 exclusion phecode
969 Poisoning by psychotropic agents Injuries & Poisonings 1.17 1.11 – 1.23 3.47e-10 1767 18683 exclusion phecode
971
Poisoning by drugs primarily affecting the
Poisoning by drugs primarily affecting the autonomic nervous system
 Injuries & Poisonings 1.2 1.03 – 1.41 0.019 168 1828 exclusion phecode
972
Poisoning by agents primarily affecting the
Poisoning by agents primarily affecting the cardiovascular system
 Injuries & Poisonings 1.34 1.17 – 1.53 1.99e-05 227 2590 exclusion phecode
972.6 Antihypertensive agents causing adverse effects Injuries & Poisonings 1.21 0.961 – 1.52 0.105 70 809 exclusion phecode
973
Poisoning by agents primarily affecting the
Poisoning by agents primarily affecting the gastrointestinal system
 Injuries & Poisonings 1.34 1.09 – 1.65 0.0055 96 1021 exclusion phecode
974
Poisoning by water, mineral, and uric acid
Poisoning by water, mineral, and uric acid metabolism drugs
 Injuries & Poisonings 1.51 1.21 – 1.89 0.00028 83 947 exclusion phecode
975
Poisoning by agents primarily acting on the
Poisoning by agents primarily acting on the smooth and skeletal muscles and respiratory system
 Injuries & Poisonings 1.37 1.06 – 1.79 0.0171 58 611 exclusion phecode
976
Poisoning by agents primarily affecting skin &
Poisoning by agents primarily affecting skin & mucous membrane, ophthalmological, otorhinolaryngological, & dental drugs
 Injuries & Poisonings 1.51 1.14 – 2 0.00434 52 555 exclusion phecode
977 Personal history of allergy to medicinal agents Injuries & Poisonings 1.2 1.04 – 1.38 0.0123 215 2208 exclusion phecode
979 Adverse drug events and drug allergies Injuries & Poisonings 1.18 1.09 – 1.29 4.99e-05 636 6637 exclusion phecode
981
Toxic effect of (non-ethyl) alcohol and
Toxic effect of (non-ethyl) alcohol and petroleum and other solvents
 Injuries & Poisonings 1.09 0.935 – 1.27 0.272 182 1903 exclusion phecode
986 Toxic effect of carbon monoxide Injuries & Poisonings 1.15 0.889 – 1.49 0.286 58 584 exclusion phecode
987 Toxic effect of other gases, fumes, or vapors Injuries & Poisonings 1.36 1.1 – 1.69 0.00514 93 988 exclusion phecode
988 Toxic effect of noxious substances eaten as food Injuries & Poisonings 1.1 0.895 – 1.35 0.368 102 1060 exclusion phecode
989
Toxic effect of other substances, chiefly
Toxic effect of other substances, chiefly nonmedicinal as to source
 Injuries & Poisonings 0.93 0.749 – 1.15 0.509 86 840 exclusion phecode
990 Effects radiation NOS Injuries & Poisonings 1.07 1.03 – 1.11 0.000459 2856 29168 exclusion phecode
994 Sepsis and SIRS Injuries & Poisonings 1.11 1.07 – 1.16 2.19e-07 2636 28313 exclusion phecode
994.2 Sepsis Injuries & Poisonings 1.11 1.07 – 1.16 2.19e-07 2636 28313 exclusion phecode
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