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Scores Type 2 diabetes UK Biobank (UKB) PheWAS analysis

Type 2 diabetes — UK Biobank (UKB) PRS PheWAS

PRS model
PRS ID exprsweb-t2d-30054458-gcst006867-prscs-ukb-20211120Legacy PRSCSPRS-CSLarge GWAS

Evaluation cohort: UK Biobank (UKB).

This page pairs the PheWAS plot with the full sortable table for the all-subject and exclusion scans.

Read the all-subject and exclusion scans separately. The combined view is only a browsing aid, and the selected-phecode panel below is only meaningful when the same phecode exists in both scans.

ExPRS exclusion definition

Exclusion cohort: individuals without Type 2 diabetes.

For this ExPRS, the exclusion sensitivity scan removes individuals with the exposure itself before rerunning the PheWAS. This is an exposure-based sensitivity analysis rather than a diagnosis-based exclusion.

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Signal overview

The plot gives a quick view of the currently visible associations. Click a point to pin its details, inspect that phecode across scans when both rows exist, or open the matching phecode detail page.

866 rows visible 17 categories
Phecode Description Category OR 95% CI P value Cases Controls Analysis Link
008 Intestinal infection Infectious Diseases 1.14 1.12 – 1.17 3.82e-34 8842 88430 all phecode
008.5 Bacterial enteritis Infectious Diseases 1.15 1.11 – 1.2 1.28e-12 2718 27172 all phecode
008.52 Intestinal infection due to C. difficile Infectious Diseases 1.12 1.03 – 1.21 0.00604 653 6533 all phecode
008.6 Viral Enteritis Infectious Diseases 1.17 1.1 – 1.26 5.72e-06 862 8622 all phecode
008.7 Intestinal infection due to protozoa Infectious Diseases 1.1 0.841 – 1.43 0.49 55 550 all phecode
010 Tuberculosis Infectious Diseases 0.926 0.79 – 1.09 0.348 166 1659 all phecode
038 Septicemia Infectious Diseases 1.14 1.11 – 1.18 1.59e-16 4175 41776 all phecode
038.1 Gram negative septicemia Infectious Diseases 1.16 1.09 – 1.25 2.07e-05 850 8501 all phecode
038.2 Gram positive septicemia Infectious Diseases 1.15 1.05 – 1.26 0.00233 494 4978 all phecode
041 Bacterial infection NOS Infectious Diseases 1.17 1.15 – 1.19 5.89e-60 12017 120377 all phecode
041.1 Staphylococcus infections Infectious Diseases 1.22 1.17 – 1.26 1.85e-26 3128 31348 all phecode
041.2 Streptococcus infection Infectious Diseases 1.15 1.09 – 1.21 8.06e-08 1641 16433 all phecode
041.4 E. coli Infectious Diseases 1.17 1.13 – 1.22 2.17e-15 2730 27319 all phecode
053 Herpes zoster Infectious Diseases 1.16 1.05 – 1.28 0.00268 411 4137 all phecode
053.1 Herpes zoster with nervous system complications Infectious Diseases 1.17 0.948 – 1.45 0.142 95 949 all phecode
054 Herpes simplex Infectious Diseases 1.05 0.911 – 1.21 0.493 211 2107 all phecode
070 Viral hepatitis Infectious Diseases 1.08 0.989 – 1.17 0.0874 590 5916 all phecode
070.1 Viral hepatitis A Infectious Diseases 1.17 0.917 – 1.5 0.205 69 690 all phecode
070.2 Viral hepatitis B Infectious Diseases 1.04 0.877 – 1.24 0.627 132 1330 all phecode
070.3 Viral hepatitis C Infectious Diseases 1.04 0.913 – 1.18 0.559 255 2568 all phecode
070.4 Chronic hepatitis Infectious Diseases 1.16 1.03 – 1.31 0.0156 276 2767 all phecode
070.9 Hepatitis NOS Infectious Diseases 1.49 1.35 – 1.64 1.37e-15 428 4287 all phecode
071 Human immunodeficiency virus [HIV] disease Infectious Diseases 0.988 0.842 – 1.16 0.883 147 1467 all phecode
071.1 HIV infection, symptomatic Infectious Diseases 0.977 0.818 – 1.17 0.793 117 1168 all phecode
078 Viral warts & HPV Infectious Diseases 1.18 1.11 – 1.26 5.2e-07 1004 10036 all phecode
079 Viral infection Infectious Diseases 1.1 1.05 – 1.14 4.44e-06 2769 27694 all phecode
079.1 Varicella infection Infectious Diseases 1.13 0.881 – 1.46 0.33 64 640 all phecode
080 Postoperative infection Infectious Diseases 1.18 1.15 – 1.22 8.51e-27 4473 44775 all phecode
081
Infection/inflammation of internal prosthetic
Infection/inflammation of internal prosthetic device; implant; and graft
 Infectious Diseases 1.14 1.09 – 1.19 7.87e-10 2477 24765 all phecode
090
Sexually transmitted infections (not HIV or
Sexually transmitted infections (not HIV or hepatitis)
 Infectious Diseases 1.22 0.957 – 1.56 0.107 71 709 all phecode
1000 Burns Injuries & Poisonings 1.05 0.96 – 1.14 0.305 578 5796 all phecode
1001 Foreign body injury Injuries & Poisonings 1.03 0.975 – 1.1 0.268 1199 12007 all phecode
1002
Symptoms concerning nutrition, metabolism, and
Symptoms concerning nutrition, metabolism, and development
 Injuries & Poisonings 1.06 1.04 – 1.09 7.8e-06 5480 54819 all phecode
1004
Other signs and symptoms involving emotional
Other signs and symptoms involving emotional state
 Injuries & Poisonings 1.1 0.982 – 1.24 0.0981 300 2997 all phecode
1005 Other symptoms Injuries & Poisonings 1.13 1.07 – 1.19 1.27e-05 1444 14422 all phecode
1006 Crushing injury Injuries & Poisonings 0.947 0.834 – 1.08 0.407 256 2558 all phecode
1007 Injury to blood vessels Injuries & Poisonings 1.07 0.946 – 1.22 0.27 256 2559 all phecode
1008 Crushing or internal injury to organs Injuries & Poisonings 1.02 0.961 – 1.09 0.475 1013 10132 all phecode
1009 Injury, NOS Injuries & Poisonings 1.07 1.05 – 1.1 7.96e-10 8482 84911 all phecode
1010 Other tests Injuries & Poisonings 1.17 1.14 – 1.2 5.2e-32 5945 59512 all phecode
1011 Complications of surgical and medical procedures Injuries & Poisonings 1.12 1.1 – 1.15 3.01e-26 9152 91588 all phecode
1012 Late effect Injuries & Poisonings 1.05 0.862 – 1.28 0.62 105 1057 all phecode
1013 Asphyxia and hypoxemia Injuries & Poisonings 1.04 0.924 – 1.16 0.538 316 3168 all phecode
1014 Effects of heat, cold and air pressure Injuries & Poisonings 1.07 0.84 – 1.37 0.572 66 659 all phecode
1015 Effects of other external causes Injuries & Poisonings 1.14 1.11 – 1.18 3.67e-17 4226 42294 all phecode
1019
Other ill-defined and unknown causes of
Other ill-defined and unknown causes of morbidity and mortality
 Injuries & Poisonings 1.1 1.09 – 1.12 2.85e-32 15895 159019 all phecode
110 Dermatophytosis / Dermatomycosis Infectious Diseases 1.16 1.03 – 1.31 0.0163 279 2810 all phecode
110.1 Dermatophytosis Infectious Diseases 1.16 1.03 – 1.31 0.0174 273 2750 all phecode
110.11 Dermatophytosis of nail Infectious Diseases 1.01 0.799 – 1.28 0.932 74 756 all phecode
110.12 Althete's foot Infectious Diseases 1.22 1.03 – 1.44 0.0211 141 1410 all phecode
112 Candidiasis Infectious Diseases 1.15 1.1 – 1.2 8.26e-10 2126 21275 all phecode
117 Mycoses Infectious Diseases 1.09 0.965 – 1.23 0.166 272 2719 all phecode
117.4 Aspergillosis Infectious Diseases 1.02 0.872 – 1.2 0.793 165 1650 all phecode
130 Spirochetal infection Infectious Diseases 0.798 0.63 – 1.01 0.0628 80 800 all phecode
133 Arthropod-borne diseases Infectious Diseases 0.866 0.673 – 1.11 0.262 69 689 all phecode
134 Helminthiases Infectious Diseases 1.12 0.935 – 1.35 0.215 127 1267 all phecode
134.1 Intestinal helminthiases Infectious Diseases 1.06 0.872 – 1.29 0.547 106 1058 all phecode
136 Other infectious and parasitic diseases Infectious Diseases 1.23 1.07 – 1.42 0.00381 205 2050 all phecode
145 Cancer of mouth Neoplasms 1.03 0.947 – 1.11 0.521 642 6415 all phecode
145.2 Cancer of tongue Neoplasms 0.998 0.888 – 1.12 0.967 310 3096 all phecode
145.3 Cancer of major salivary glands Neoplasms 1.2 0.985 – 1.47 0.0704 105 1049 all phecode
145.5 Cancer of the mouth floor Neoplasms 0.9 0.678 – 1.19 0.466 54 539 all phecode
149 Cancer of larynx, pharynx, nasal cavities Neoplasms 1.1 1.02 – 1.19 0.0162 635 6342 all phecode
149.1 Cancer of oropharynx Neoplasms 1.13 0.99 – 1.29 0.0697 252 2517 all phecode
149.4 Cancer of larynx Neoplasms 1.12 0.989 – 1.26 0.0745 265 2640 all phecode
149.9 Cancer of of nasal cavities Neoplasms 1.07 0.819 – 1.39 0.635 57 570 all phecode
150 Cancer of esophagus Neoplasms 1.06 0.984 – 1.14 0.124 762 7630 all phecode
151 Cancer of stomach Neoplasms 1.08 0.997 – 1.18 0.0599 569 5696 all phecode
153 Colorectal cancer Neoplasms 1.06 1.03 – 1.09 0.000304 4580 45799 all phecode
153.2 Colon cancer Neoplasms 1.06 1.02 – 1.1 0.00129 3105 31046 all phecode
153.3
Malignant neoplasm of rectum, rectosigmoid
Malignant neoplasm of rectum, rectosigmoid junction, and anus
 Neoplasms 1.04 0.997 – 1.09 0.0701 2164 21640 all phecode
155 Cancer of liver and intrahepatic bile duct Neoplasms 1.27 1.15 – 1.4 3.19e-06 400 4008 all phecode
155.1 Malignant neoplasm of liver, primary Neoplasms 1.4 1.2 – 1.63 2.09e-05 158 1580 all phecode
157 Pancreatic cancer Neoplasms 1.21 1.12 – 1.31 9.73e-07 659 6582 all phecode
158
Neoplasm of unspecified nature of digestive
Neoplasm of unspecified nature of digestive system
 Neoplasms 1.01 0.952 – 1.08 0.676 1063 10635 all phecode
159
Malignant neoplasm of other and ill-defined
Malignant neoplasm of other and ill-defined sites within the digestive organs and peritoneum
 Neoplasms 1.07 1.04 – 1.1 3.58e-07 5567 55694 all phecode
159.2
Malignant neoplasm of small intestine
Malignant neoplasm of small intestine, including duodenum
 Neoplasms 1.06 0.919 – 1.23 0.411 190 1900 all phecode
159.3
Malignant neoplasm of gallbladder and
Malignant neoplasm of gallbladder and extrahepatic bile ducts
 Neoplasms 1.13 0.984 – 1.3 0.0833 205 2048 all phecode
159.4
Malignant neoplasm of retroperitoneum and
Malignant neoplasm of retroperitoneum and peritoneum
 Neoplasms 1.13 0.981 – 1.31 0.0895 193 1925 all phecode
164 Cancer of intrathoracic organs Neoplasms 1.05 0.804 – 1.38 0.712 60 600 all phecode
165 Cancer within the respiratory system Neoplasms 1.12 1.08 – 1.16 3.84e-09 2824 28235 all phecode
165.1 Cancer of bronchus; lung Neoplasms 1.11 1.07 – 1.16 1.09e-06 2230 22307 all phecode
170 Cancer of bone and connective tissue Neoplasms 0.95 0.861 – 1.05 0.313 437 4364 all phecode
170.1 Bone cancer Neoplasms 0.931 0.777 – 1.12 0.439 131 1309 all phecode
170.2 Cancer of connective tissue Neoplasms 0.975 0.871 – 1.09 0.664 331 3303 all phecode
172 Skin cancer Neoplasms 0.992 0.975 – 1.01 0.366 13495 134987 all phecode
172.1 Melanomas of skin, dx or hx Neoplasms 0.975 0.937 – 1.01 0.202 2681 26792 all phecode
172.11 Melanomas of skin Neoplasms 0.977 0.939 – 1.02 0.243 2713 27112 all phecode
172.2 Other non-epithelial cancer of skin Neoplasms 0.992 0.973 – 1.01 0.444 11000 110056 all phecode
172.3 Carcinoma in situ of skin Neoplasms 1.01 0.934 – 1.09 0.805 666 6656 all phecode
173 Neoplasm of uncertain behavior of skin Neoplasms 1.11 0.958 – 1.29 0.16 181 1818 all phecode
174 Breast cancer Neoplasms 1.02 1 – 1.04 0.0487 12686 126597 all phecode
174.1 Breast cancer [female] Neoplasms 1.02 1 – 1.04 0.0307 12476 124506 all phecode
174.11 Malignant neoplasm of female breast Neoplasms 1.02 1 – 1.04 0.0425 11757 117502 all phecode
174.3 Neoplasm of uncertain behavior of breast Neoplasms 1.1 0.901 – 1.34 0.353 115 1148 all phecode
175 Acquired absence of breast Neoplasms 1.03 0.99 – 1.08 0.138 2400 24010 all phecode
180 Cervical cancer and dysplasia Neoplasms 1.02 0.979 – 1.07 0.309 2174 21747 all phecode
180.1 Cervical cancer Neoplasms 0.954 0.841 – 1.08 0.46 272 2720 all phecode
180.3
Cervical intraepithelial neoplasia [CIN]
Cervical intraepithelial neoplasia [CIN] [Cervical dysplasia]
 Neoplasms 1.04 0.992 – 1.09 0.102 2078 20784 all phecode
182 Malignant neoplasm of uterus Neoplasms 1.06 1 – 1.12 0.0409 1282 12836 all phecode
184 Cancer of other female genital organs Neoplasms 1.08 1.02 – 1.14 0.00779 1378 13772 all phecode
184.1
Malignant neoplasm of ovary and other uterine
Malignant neoplasm of ovary and other uterine adnexa
 Neoplasms 1.06 0.995 – 1.14 0.0685 967 9667 all phecode
184.11 Malignant neoplasm of ovary Neoplasms 1.07 1 – 1.15 0.0451 939 9387 all phecode
184.2
Cancer of other female genital organs
Cancer of other female genital organs (excluding uterus and ovary)
 Neoplasms 1.07 0.954 – 1.21 0.237 305 3049 all phecode
185 Cancer of prostate Neoplasms 1 0.975 – 1.03 0.937 5974 58812 all phecode
187 Cancer of other male genital organs Neoplasms 1.07 0.971 – 1.18 0.171 449 4485 all phecode
187.1
Malignant neoplasm of unspecified male genital
Malignant neoplasm of unspecified male genital organ
 Neoplasms 1.06 0.831 – 1.36 0.627 70 700 all phecode
187.2 Malignant neoplasm of testis Neoplasms 1.01 0.893 – 1.13 0.925 287 2868 all phecode
187.8
Neoplasm of uncertain behavior of male genital
Neoplasm of uncertain behavior of male genital organs
 Neoplasms 1.14 0.93 – 1.39 0.212 110 1098 all phecode
189
Cancer of urinary organs (incl. kidney and
Cancer of urinary organs (incl. kidney and bladder)
 Neoplasms 1.1 1.06 – 1.13 4.21e-09 4160 41604 all phecode
189.1 Cancer of kidney and renal pelvis Neoplasms 1.12 1.05 – 1.19 0.000288 1073 10723 all phecode
189.11 Malignant neoplasm of kidney, except pelvis Neoplasms 1.14 1.07 – 1.22 2.84e-05 1033 10324 all phecode
189.12 Malignant neoplasm of renal pelvis Neoplasms 0.849 0.664 – 1.09 0.191 66 660 all phecode
189.2 Cancer of bladder Neoplasms 1.11 1.07 – 1.16 4.21e-07 2409 24113 all phecode
189.21 Malignant neoplasm of bladder Neoplasms 1.11 1.06 – 1.16 1.86e-06 2142 21447 all phecode
189.4 Malignant neoplasm of other urinary organs Neoplasms 0.875 0.735 – 1.04 0.135 144 1439 all phecode
190 Cancer of eye Neoplasms 1 0.863 – 1.17 0.966 176 1758 all phecode
191
Manlignant and unknown neoplasms of brain and
Manlignant and unknown neoplasms of brain and nervous system
 Neoplasms 1.01 0.932 – 1.09 0.829 689 6879 all phecode
191.1 Cancer of brain and nervous system Neoplasms 1 0.921 – 1.09 0.932 566 5650 all phecode
191.11 Cancer of brain Neoplasms 1 0.917 – 1.1 0.946 525 5240 all phecode
193 Thyroid cancer Neoplasms 1.11 0.993 – 1.23 0.068 346 3466 all phecode
194 Cancer of other endocrine glands Neoplasms 0.997 0.805 – 1.23 0.975 95 949 all phecode
195 Cancer, suspected or other Neoplasms 1.06 1.04 – 1.08 1.35e-12 16967 165463 all phecode
195.1 Malignant neoplasm, other Neoplasms 1.06 1.04 – 1.07 5.56e-12 16267 159497 all phecode
197 Chemotherapy Neoplasms 1.1 1.09 – 1.12 4.33e-44 21433 213213 all phecode
198 Secondary malignant neoplasm Neoplasms 1.07 1.05 – 1.09 1.31e-10 9552 95503 all phecode
198.1 Secondary malignancy of lymph nodes Neoplasms 1.05 1.02 – 1.08 0.0015 5368 53670 all phecode
198.2 Secondary malignancy of respiratory organs Neoplasms 1.06 1.02 – 1.11 0.00815 2267 22670 all phecode
198.3
Secondary malignant neoplasm of digestive
Secondary malignant neoplasm of digestive systems
 Neoplasms 1.06 1 – 1.11 0.034 1549 15496 all phecode
198.4 Secondary malignant neoplasm of liver Neoplasms 1.06 1.02 – 1.1 0.00446 2665 26648 all phecode
198.5 Secondary malignancy of brain/spine Neoplasms 1.01 0.942 – 1.09 0.761 848 8473 all phecode
198.6 Secondary malignancy of bone Neoplasms 1.1 1.05 – 1.15 2.27e-05 2161 21600 all phecode
198.7 Secondary malignant neoplasm of skin Neoplasms 1.04 0.89 – 1.21 0.647 188 1890 all phecode
199 Neoplasm of uncertain behavior Neoplasms 1.1 1.04 – 1.16 0.000898 1432 14313 all phecode
199.4 Neurofibromatosis Neoplasms 1 0.818 – 1.23 0.965 95 950 all phecode
200 Myeloproliferative disease Neoplasms 1.16 1.09 – 1.24 3.05e-06 991 9911 all phecode
200.1 Polycythemia vera Neoplasms 1.18 1.06 – 1.3 0.00167 387 3867 all phecode
201 Hodgkin's disease Neoplasms 0.996 0.88 – 1.13 0.953 259 2598 all phecode
202 Cancer of other lymphoid, histiocytic tissue Neoplasms 1.02 0.975 – 1.06 0.423 2264 22709 all phecode
202.2 Non-Hodgkins lymphoma Neoplasms 0.999 0.952 – 1.05 0.959 1802 18073 all phecode
202.21 Nodular lymphoma Neoplasms 0.955 0.858 – 1.06 0.394 363 3647 all phecode
202.24 Large cell lymphoma Neoplasms 1.06 0.973 – 1.15 0.185 581 5824 all phecode
204 Leukemia Neoplasms 1.1 1.05 – 1.15 2e-04 1660 16630 all phecode
204.1 Lymphoid leukemia Neoplasms 1.12 1.03 – 1.22 0.00578 577 5784 all phecode
204.11 Lymphoid leukemia, acute Neoplasms 1.14 0.879 – 1.49 0.316 56 560 all phecode
204.12 Lymphoid leukemia, chronic Neoplasms 1.13 1.04 – 1.24 0.00544 507 5084 all phecode
204.2 Myeloid leukemia Neoplasms 1.11 1.01 – 1.22 0.0291 462 4617 all phecode
204.21 Myeloid leukemia, acute Neoplasms 1.09 0.977 – 1.22 0.121 329 3287 all phecode
204.22 Myeloid leukemia, chronic Neoplasms 1.1 0.92 – 1.31 0.297 144 1440 all phecode
204.4 Multiple myeloma Neoplasms 1.04 0.951 – 1.13 0.419 555 5560 all phecode
208 Benign neoplasm of colon Neoplasms 1.09 1.08 – 1.11 1.79e-32 19856 191891 all phecode
210 Benign neoplasm of lip, oral cavity, and pharynx Neoplasms 1.08 1.01 – 1.15 0.0209 978 9781 all phecode
211
Benign neoplasm of other parts of digestive
Benign neoplasm of other parts of digestive system
 Neoplasms 1.11 1.08 – 1.14 2.32e-12 5243 52452 all phecode
212
Benign neoplasm of respiratory and
Benign neoplasm of respiratory and intrathoracic organs
 Neoplasms 1.13 1.01 – 1.26 0.0266 347 3466 all phecode
213 Benign neoplasm of bone and articular cartilage Neoplasms 1.03 0.914 – 1.15 0.667 318 3187 all phecode
214 Lipoma Neoplasms 1.07 1.04 – 1.1 5.23e-07 6231 62346 all phecode
214.1 Lipoma of skin and subcutaneous tissue Neoplasms 1.06 1.03 – 1.1 8.66e-05 4585 45872 all phecode
215
Other benign neoplasm of connective and other
Other benign neoplasm of connective and other soft tissue
 Neoplasms 1.04 0.978 – 1.11 0.214 1107 11061 all phecode
216 Benign neoplasm of skin Neoplasms 1.01 0.991 – 1.04 0.216 7664 76660 all phecode
217 Vascular hamartomas and non-neoplastic nevi Neoplasms 1.04 0.96 – 1.13 0.322 632 6313 all phecode
217.1 Nevus, non-neoplastic Neoplasms 1.05 0.963 – 1.14 0.282 595 5943 all phecode
218 Benign neoplasm of uterus Neoplasms 1.07 1.05 – 1.09 2.54e-10 10023 100200 all phecode
218.1 Uterine leiomyoma Neoplasms 1.06 1.04 – 1.09 1.83e-09 10241 102376 all phecode
218.2 Other benign neoplasm of uterus Neoplasms 1.06 0.949 – 1.18 0.306 355 3548 all phecode
220 Benign neoplasm of ovary Neoplasms 1.04 0.989 – 1.1 0.121 1445 14483 all phecode
221 Benign neoplasm of other female genital organs Neoplasms 1.03 0.893 – 1.19 0.686 220 2196 all phecode
222 Benign neoplasm of male genital organs Neoplasms 1.12 0.952 – 1.31 0.174 160 1600 all phecode
223
Benign neoplasm of kidney and other urinary
Benign neoplasm of kidney and other urinary organs
 Neoplasms 1.22 1.04 – 1.43 0.0121 173 1729 all phecode
224 Benign neoplasm of eye Neoplasms 1 0.836 – 1.2 1 129 1299 all phecode
224.1 Benign neoplasm of eye, uveal Neoplasms 1.04 0.82 – 1.33 0.731 67 680 all phecode
225
Benign neoplasm of brain and other parts of
Benign neoplasm of brain and other parts of nervous system
 Neoplasms 1.06 0.989 – 1.14 0.0989 816 8155 all phecode
225.1
Benign neoplasm of brain, cranial nerves
Benign neoplasm of brain, cranial nerves, meninges
 Neoplasms 1.05 0.976 – 1.13 0.19 775 7756 all phecode
225.2 Benign neoplasm of spinal cord, meninges Neoplasms 1.26 0.969 – 1.63 0.0846 59 589 all phecode
226 Benign neoplasm of thyroid glands Neoplasms 1.06 0.929 – 1.2 0.401 266 2664 all phecode
227
Benign neoplasm of other endocrine glands and
Benign neoplasm of other endocrine glands and related structures
 Neoplasms 1.11 1.04 – 1.19 0.00221 861 8635 all phecode
227.1 Benign neoplasm of adrenal gland Neoplasms 1.17 1.01 – 1.35 0.0379 186 1857 all phecode
227.2 Benign neoplasm of parathyroid gland Neoplasms 1.1 0.988 – 1.22 0.0818 371 3709 all phecode
227.3
Benign neoplasm of pituitary gland and
Benign neoplasm of pituitary gland and craniopharyngeal duct (pouch)
 Neoplasms 1.12 0.999 – 1.26 0.052 309 3114 all phecode
228 Hemangioma and lymphangioma, any site Neoplasms 1.04 0.985 – 1.09 0.174 1596 15966 all phecode
229 Benign neoplasm of unspecified sites Neoplasms 1.03 0.989 – 1.08 0.15 2397 23955 all phecode
240 Simple and unspecified goiter Endocrine/metabolic 1.19 1.09 – 1.29 5.29e-05 600 6016 all phecode
241 Nontoxic nodular goiter Endocrine/metabolic 1.06 0.995 – 1.13 0.0732 1107 11092 all phecode
241.1 Nontoxic uninodular goiter Endocrine/metabolic 1.09 0.987 – 1.2 0.092 471 4706 all phecode
241.2 Nontoxic multinodular goiter Endocrine/metabolic 1.02 0.941 – 1.1 0.637 676 6784 all phecode
242 Thyrotoxicosis with or without goiter Endocrine/metabolic 1.2 1.15 – 1.26 1.2e-14 1854 18531 all phecode
242.1 Graves' disease Endocrine/metabolic 1.26 1.14 – 1.39 2.47e-06 456 4553 all phecode
242.2 Toxic multinodular goiter Endocrine/metabolic 1.11 0.896 – 1.37 0.344 91 910 all phecode
242.3 Exophthalmos Endocrine/metabolic 1.18 0.992 – 1.4 0.0621 138 1379 all phecode
244 Hypothyroidism Endocrine/metabolic 1.16 1.14 – 1.18 1.54e-65 14590 145053 all phecode
244.1 Secondary hypothyroidism Endocrine/metabolic 1.19 1.12 – 1.27 1.78e-08 1108 11079 all phecode
244.2 Acquired hypothyroidism Endocrine/metabolic 1.14 0.936 – 1.4 0.188 101 1010 all phecode
244.4 Hypothyroidism NOS Endocrine/metabolic 1.16 1.14 – 1.18 4.76e-62 13918 138926 all phecode
245 Thyroiditis Endocrine/metabolic 0.977 0.866 – 1.1 0.7 288 2877 all phecode
245.2 Chronic thyroiditis Endocrine/metabolic 1.07 0.931 – 1.23 0.348 218 2177 all phecode
245.21 Chronic lymphocytic thyroiditis Endocrine/metabolic 1.07 0.927 – 1.23 0.367 210 2097 all phecode
246 Other disorders of thyroid Endocrine/metabolic 1.15 1.04 – 1.27 0.00841 397 3975 all phecode
250 Diabetes mellitus Endocrine/metabolic 3.61 3.55 – 3.68 3.26e-4221 19787 186006 all phecode
250.1 Type 1 diabetes Endocrine/metabolic 2.72 2.61 – 2.84 9.44e-444 2758 27621 all phecode
250.11 Type 1 diabetes with ketoacidosis Endocrine/metabolic 2.12 1.83 – 2.45 7.63e-24 239 2389 all phecode
250.12 Type 1 diabetes with renal manifestations Endocrine/metabolic 2.81 2.17 – 3.65 6.99e-15 76 770 all phecode
250.13 Type 1 diabetes with ophthalmic manifestations Endocrine/metabolic 2.76 2.48 – 3.06 1.12e-79 473 4744 all phecode
250.14 Type 1 diabetes with neurological manifestations Endocrine/metabolic 2.97 2.46 – 3.58 8.29e-30 160 1610 all phecode
250.2 Type 2 diabetes Endocrine/metabolic 4.14 4.06 – 4.22 2.19e-4213 17831 170202 all phecode
250.21 Type 2 diabetes with ketoacidosis Endocrine/metabolic 3.34 2.61 – 4.28 1.5e-21 104 1050 all phecode
250.22 Type 2 diabetes with renal manifestations Endocrine/metabolic 3.92 3.28 – 4.68 1.24e-50 200 2018 all phecode
250.23 Type 2 diabetes with ophthalmic manifestations Endocrine/metabolic 5.07 4.63 – 5.55 2.27e-272 986 9907 all phecode
250.24 Type 2 diabetes with neurological manifestations Endocrine/metabolic 4.54 4.03 – 5.12 3.44e-135 503 5066 all phecode
250.4 Abnormal glucose Endocrine/metabolic 1.95 1.79 – 2.11 1.52e-56 680 6827 all phecode
250.41 Impaired fasting glucose Endocrine/metabolic 1.84 1.61 – 2.09 4.98e-20 265 2659 all phecode
250.42 Other abnormal glucose Endocrine/metabolic 2.01 1.81 – 2.24 3.05e-39 416 4178 all phecode
250.5 Glycosuria or Acetonuria Endocrine/metabolic 1.55 1.28 – 1.88 6.19e-06 131 1308 all phecode
250.6 Polyneuropathy in diabetes Endocrine/metabolic 4.26 3.71 – 4.9 1.4e-91 349 3495 all phecode
250.7 Diabetic retinopathy Endocrine/metabolic 3.04 2.86 – 3.24 1.08e-268 1329 13335 all phecode
251.1 Hypoglycemia Endocrine/metabolic 2.56 2.38 – 2.75 6.56e-137 932 9370 all phecode
252 Disorders of parathyroid gland Endocrine/metabolic 1.18 1.1 – 1.27 2.08e-06 873 8719 all phecode
252.1 Hyperparathyroidism Endocrine/metabolic 1.17 1.08 – 1.25 4.17e-05 781 7802 all phecode
252.2 Hypoparathyroidism Endocrine/metabolic 1.53 1.29 – 1.8 6.75e-07 142 1418 all phecode
253
Disorders of the pituitary gland and its
Disorders of the pituitary gland and its hypothalamic control
 Endocrine/metabolic 1.19 1.1 – 1.28 1.64e-05 681 6821 all phecode
253.1 Pituitary hyperfunction Endocrine/metabolic 1.24 1.07 – 1.44 0.00497 187 1867 all phecode
253.11 Acromegaly and gigantism Endocrine/metabolic 1.35 1.09 – 1.67 0.00524 95 949 all phecode
253.2 Pituitary hypofunction Endocrine/metabolic 1.23 1.08 – 1.39 0.00154 260 2618 all phecode
253.3 Diabetes insipidus Endocrine/metabolic 1.29 1.05 – 1.59 0.017 92 919 all phecode
253.7 Other disorders of neurohypophysis Endocrine/metabolic 1.11 0.937 – 1.31 0.231 158 1578 all phecode
255 Disorders of adrenal glands Endocrine/metabolic 1.22 1.13 – 1.33 9.41e-07 638 6374 all phecode
255.1 Adrenal hyperfunction Endocrine/metabolic 1.32 1.14 – 1.54 0.000302 180 1797 all phecode
255.11 Cushing's syndrome Endocrine/metabolic 1.32 1.08 – 1.63 0.00754 103 1029 all phecode
255.12 Hyperaldosteronism Endocrine/metabolic 1.39 1.11 – 1.74 0.00391 76 759 all phecode
255.2 Adrenal hypofunction Endocrine/metabolic 1.14 1.03 – 1.27 0.0159 362 3617 all phecode
255.21 Glucocorticoid deficiency Endocrine/metabolic 1.14 1.03 – 1.27 0.0155 361 3607 all phecode
256 Ovarian dysfunction Endocrine/metabolic 1.21 1.06 – 1.38 0.006 240 2397 all phecode
256.4 Polycystic ovaries Endocrine/metabolic 1.21 1.05 – 1.4 0.00826 209 2088 all phecode
257 Testicular dysfunction Endocrine/metabolic 1.23 1.04 – 1.45 0.0161 160 1619 all phecode
257.1 Testicular hypofunction Endocrine/metabolic 1.29 1.09 – 1.53 0.00315 152 1539 all phecode
258 Iatrogenic endocrine disorders Endocrine/metabolic 1.28 1.05 – 1.54 0.0123 102 1020 all phecode
259 Other endocrine disorders Endocrine/metabolic 1.21 1.02 – 1.44 0.0297 149 1498 all phecode
260 Protein-calorie malnutrition Endocrine/metabolic 1.12 0.972 – 1.29 0.118 202 2018 all phecode
260.1 Cachexia Endocrine/metabolic 1.23 0.943 – 1.62 0.125 51 510 all phecode
260.6 Anorexia Endocrine/metabolic 1.1 1.02 – 1.18 0.00928 830 8317 all phecode
261 Vitamin deficiency Endocrine/metabolic 1.21 1.14 – 1.29 2.03e-10 1199 11974 all phecode
261.2 Vitamin B-complex deficiencies Endocrine/metabolic 1.22 1.13 – 1.31 2.87e-07 755 7541 all phecode
261.4 Vitamin D deficiency Endocrine/metabolic 1.2 1.09 – 1.32 0.000293 447 4462 all phecode
261.41 Rickets or osteomalacia Endocrine/metabolic 1.14 0.907 – 1.44 0.257 77 769 all phecode
262 Mineral deficiency NEC Endocrine/metabolic 1.17 1.02 – 1.33 0.0208 241 2407 all phecode
269 Proteinuria Endocrine/metabolic 1.34 1.2 – 1.49 1.68e-07 338 3378 all phecode
270
Disorders of protein plasma/amino-acid
Disorders of protein plasma/amino-acid transport and metabolism
 Endocrine/metabolic 1.01 0.896 – 1.13 0.914 303 3028 all phecode
270.3 Disorders of plasma protein metabolism Endocrine/metabolic 0.998 0.881 – 1.13 0.974 261 2608 all phecode
270.32 Paraproteinemia Endocrine/metabolic 1.08 0.933 – 1.24 0.309 191 1910 all phecode
270.33 Amyloidosis Endocrine/metabolic 1.13 0.94 – 1.36 0.193 113 1129 all phecode
270.35 Macroglobulinemia Endocrine/metabolic 0.758 0.593 – 0.968 0.0261 69 689 all phecode
271
Disorders of carbohydrate transport and
Disorders of carbohydrate transport and metabolism
 Endocrine/metabolic 1.55 1.31 – 1.84 3.43e-07 160 1600 all phecode
271.3
Intestinal disaccharidase deficiencies and
Intestinal disaccharidase deficiencies and disaccharide malabsorption
 Endocrine/metabolic 1.52 1.27 – 1.82 5.27e-06 139 1391 all phecode
272 Disorders of lipoid metabolism Endocrine/metabolic 1.32 1.3 – 1.33 3.09e-497 34835 235433 all phecode
272.1 Hyperlipidemia Endocrine/metabolic 1.32 1.3 – 1.33 8.29e-498 34764 235203 all phecode
272.11 Hypercholesterolemia Endocrine/metabolic 1.32 1.3 – 1.33 4.61e-467 32324 228083 all phecode
272.12 Hyperglyceridemia Endocrine/metabolic 1.59 1.21 – 2.09 0.000849 58 580 all phecode
272.13 Mixed hyperlipidemia Endocrine/metabolic 1.75 1.49 – 2.05 7.65e-12 164 1637 all phecode
272.9 Unspecified disorder of lipoid metabolism Endocrine/metabolic 1.46 1.28 – 1.67 4.32e-08 211 2109 all phecode
274 Gout and other crystal arthropathies Endocrine/metabolic 1.26 1.22 – 1.3 9.63e-43 3724 37231 all phecode
274.1 Gout Endocrine/metabolic 1.27 1.22 – 1.31 2.58e-38 3171 31705 all phecode
274.11 Gouty arthropathy Endocrine/metabolic 1.33 1.11 – 1.6 0.00205 112 1119 all phecode
274.2 Crystal arthropathies Endocrine/metabolic 1.23 1.13 – 1.33 7.85e-07 613 6124 all phecode
274.21 Chondrocalcinosis Endocrine/metabolic 1.24 1.13 – 1.35 1.35e-06 558 5576 all phecode
275 Disorders of mineral metabolism Endocrine/metabolic 1.15 1.1 – 1.2 5.26e-10 2107 21070 all phecode
275.1 Disorders of iron metabolism Hematopoietic 1.08 0.994 – 1.17 0.0688 653 6535 all phecode
275.3 Disorders of magnesium metabolism Endocrine/metabolic 1.3 1.17 – 1.44 7.19e-07 375 3745 all phecode
275.5 Disorders of calcium/phosphorus metabolism Endocrine/metabolic 1.17 1.1 – 1.24 2.25e-07 1202 12019 all phecode
275.53 Disorders of phosphorus metabolism Endocrine/metabolic 1.29 1.11 – 1.51 0.000833 171 1717 all phecode
276
Disorders of fluid, electrolyte, and acid-base
Disorders of fluid, electrolyte, and acid-base balance
 Endocrine/metabolic 1.23 1.2 – 1.26 1.13e-63 7284 72932 all phecode
276.1 Electrolyte imbalance Endocrine/metabolic 1.22 1.18 – 1.26 1.22e-34 4086 40930 all phecode
276.11 Hyperosmolality and/or hypernatremia Endocrine/metabolic 1.33 1.17 – 1.52 2.04e-05 239 2409 all phecode
276.12 Hyposmolality and/or hyponatremia Endocrine/metabolic 1.15 1.1 – 1.2 1.2e-08 1818 18200 all phecode
276.13 Hyperpotassemia Endocrine/metabolic 1.47 1.38 – 1.57 1.22e-31 969 9728 all phecode
276.14 Hypopotassemia Endocrine/metabolic 1.14 1.08 – 1.2 2e-06 1424 14235 all phecode
276.4 Acid-base balance disorder Endocrine/metabolic 1.32 1.25 – 1.41 2.51e-20 1161 11629 all phecode
276.41 Acidosis Endocrine/metabolic 1.33 1.25 – 1.42 1.89e-19 1056 10577 all phecode
276.42 Alkalosis Endocrine/metabolic 1.18 0.974 – 1.43 0.091 113 1129 all phecode
276.5 Hypovolemia Endocrine/metabolic 1.23 1.19 – 1.28 7.56e-27 2827 28265 all phecode
276.6 Fluid overload Endocrine/metabolic 1.38 1.26 – 1.52 1.19e-11 451 4535 all phecode
276.8 Polydipsia Endocrine/metabolic 1.25 1.04 – 1.49 0.0152 128 1278 all phecode
277 Other disorders of metabolism Endocrine/metabolic 1.11 1.03 – 1.19 0.00345 899 8977 all phecode
277.4 Disorders of bilirubin excretion Endocrine/metabolic 1.06 0.954 – 1.18 0.273 362 3613 all phecode
277.5 Other disorders of lipoid metabolism Endocrine/metabolic 1.31 1.15 – 1.49 4.47e-05 230 2298 all phecode
277.51 Lipoprotein disorders Endocrine/metabolic 1.17 0.907 – 1.52 0.223 52 520 all phecode
278 Overweight, obesity and other hyperalimentation Endocrine/metabolic 1.45 1.42 – 1.48 6.61e-302 10804 108289 all phecode
278.1 Obesity Endocrine/metabolic 1.46 1.43 – 1.49 5.65e-302 10642 106670 all phecode
278.3 Localized adiposity Endocrine/metabolic 1.19 0.956 – 1.47 0.121 84 838 all phecode
278.4 Abnormal weight gain Endocrine/metabolic 1.55 1.23 – 1.97 0.00027 66 660 all phecode
279 Disorders involving the immune mechanism Endocrine/metabolic 0.977 0.858 – 1.11 0.722 250 2510 all phecode
279.1 Immunity deficiency Endocrine/metabolic 0.98 0.85 – 1.13 0.786 209 2100 all phecode
279.11 Deficiency of humoral immunity Endocrine/metabolic 0.865 0.725 – 1.03 0.109 138 1390 all phecode
279.7 Other immunological findings Endocrine/metabolic 0.994 0.874 – 1.13 0.925 248 2478 all phecode
280 Iron deficiency anemias Hematopoietic 1.2 1.17 – 1.23 1.03e-53 7610 76168 all phecode
280.1
Iron deficiency anemias, unspecified or not due
Iron deficiency anemias, unspecified or not due to blood loss
 Hematopoietic 1.21 1.18 – 1.23 7.18e-54 7311 73153 all phecode
280.2
Iron deficiency anemia secondary to blood loss
Iron deficiency anemia secondary to blood loss (chronic)
 Hematopoietic 1.12 1.01 – 1.23 0.0251 452 4541 all phecode
281 Other deficiency anemia Hematopoietic 1.22 1.15 – 1.3 1.26e-10 1112 11126 all phecode
281.1 Megaloblastic anemia Hematopoietic 1.22 1.15 – 1.3 2.67e-10 1066 10669 all phecode
281.11 Pernicious anemia Hematopoietic 1.24 1.15 – 1.34 1.07e-08 750 7514 all phecode
281.12 Other vitamin B12 deficiency anemia Hematopoietic 1.37 1.18 – 1.59 5.17e-05 177 1769 all phecode
281.13 Folate-deficiency anemia Hematopoietic 1.07 0.922 – 1.25 0.362 183 1836 all phecode
281.9 Deficiency anemias Hematopoietic 1.19 0.897 – 1.58 0.227 54 538 all phecode
282 Hereditary hemolytic anemias Hematopoietic 1.27 1.08 – 1.49 0.00411 150 1499 all phecode
282.8 Other hemoglobinopathies Hematopoietic 1.21 0.938 – 1.56 0.142 56 560 all phecode
282.9 Other hereditary hemolytic anemias Hematopoietic 1.21 0.968 – 1.51 0.0933 85 849 all phecode
283 Acquired hemolytic anemias Hematopoietic 1.14 0.952 – 1.36 0.157 135 1377 all phecode
283.1 Autoimmune hemolytic anemias Hematopoietic 1.12 0.919 – 1.36 0.262 103 1059 all phecode
284 Aplastic anemia Hematopoietic 1.16 1.05 – 1.28 0.00357 435 4357 all phecode
285 Other anemias Hematopoietic 1.16 1.13 – 1.18 3.8e-53 12104 121094 all phecode
285.1 Acute posthemorrhagic anemia Hematopoietic 1.04 0.923 – 1.18 0.491 271 2707 all phecode
285.2 Anemia of chronic disease Hematopoietic 1.17 1.09 – 1.27 5.79e-05 697 6980 all phecode
285.22 Anemia in neoplastic disease Hematopoietic 1.03 0.928 – 1.14 0.601 414 4147 all phecode
286 Coagulation defects Hematopoietic 1.12 1.05 – 1.2 0.00101 921 9218 all phecode
286.1 Congenital coagulation defects Hematopoietic 1.13 1.03 – 1.24 0.0133 459 4594 all phecode
286.11 Von willebrand's disease Hematopoietic 1.09 0.889 – 1.35 0.393 96 959 all phecode
286.12
Congenital deficiency of other clotting factors
Congenital deficiency of other clotting factors (including factor VII)
 Hematopoietic 1.14 1.01 – 1.29 0.0291 294 2944 all phecode
286.13 Congenital factor VIII disorder Hematopoietic 1.21 0.94 – 1.56 0.138 63 630 all phecode
286.5
Hemorrhagic disorder due to intrinsic
Hemorrhagic disorder due to intrinsic circulating anticoagulants
 Hematopoietic 1.08 0.877 – 1.33 0.465 86 860 all phecode
286.7 Other and unspecified coagulation defects Hematopoietic 1.08 0.976 – 1.2 0.134 386 3867 all phecode
287 Purpura and other hemorrhagic conditions Hematopoietic 1.11 1.06 – 1.17 3.73e-05 1652 16532 all phecode
287.1 Spontaneous ecchymoses Hematopoietic 1.16 0.972 – 1.38 0.101 129 1290 all phecode
287.2 Allergic purpura Hematopoietic 1.11 0.824 – 1.5 0.491 51 510 all phecode
287.3 Thrombocytopenia Hematopoietic 1.1 1.05 – 1.16 0.000201 1553 15543 all phecode
287.31 Primary thrombocytopenia Hematopoietic 1.15 1.04 – 1.27 0.0079 419 4195 all phecode
287.32 Secondary thrombocytopenia Hematopoietic 1.05 0.822 – 1.34 0.699 75 749 all phecode
288 Diseases of white blood cells Hematopoietic 1.05 1.01 – 1.08 0.00874 3765 37672 all phecode
288.1 Decreased white blood cell count Hematopoietic 1.03 0.998 – 1.07 0.0648 3168 31704 all phecode
288.11 Neutropenia Hematopoietic 1.04 0.999 – 1.07 0.0588 3176 31784 all phecode
288.3 Eosinophilia Hematopoietic 1.05 0.834 – 1.33 0.664 71 709 all phecode
289 Other diseases of blood and blood-forming organs Hematopoietic 1.07 1 – 1.15 0.0422 862 8625 all phecode
289.3
Personal history of diseases of blood and
Personal history of diseases of blood and blood-forming organs
 Hematopoietic 1.07 0.947 – 1.2 0.286 290 2897 all phecode
289.4 Lymphadenitis Hematopoietic 1.06 1.02 – 1.11 0.00288 2602 26061 all phecode
289.5 Diseases of spleen Hematopoietic 1.12 1.03 – 1.23 0.0122 516 5153 all phecode
289.8 Polycythemia, secondary Hematopoietic 1.15 1.02 – 1.29 0.0211 292 2917 all phecode
289.9 Abnormality of red blood cells Hematopoietic 1.29 1.04 – 1.6 0.0208 90 900 all phecode
290
Delirium dementia and amnestic and other
Delirium dementia and amnestic and other cognitive disorders
 Mental Disorders 1.11 1.06 – 1.16 1.29e-05 1929 19281 all phecode
290.1 Dementias Mental Disorders 1.1 1.03 – 1.18 0.00264 1004 10032 all phecode
290.11 Alzheimer's disease Mental Disorders 1.08 0.978 – 1.19 0.133 431 4307 all phecode
290.16 Vascular dementia Mental Disorders 1.24 1.08 – 1.43 0.00254 201 2008 all phecode
290.2 Delirium due to conditions classified elsewhere Mental Disorders 1.13 1.05 – 1.23 0.00202 650 6501 all phecode
290.3
Other persistent mental disorders due to
Other persistent mental disorders due to conditions classified elsewhere
 Mental Disorders 0.975 0.769 – 1.24 0.838 70 709 all phecode
291
Other specified nonpsychotic and/or transient
Other specified nonpsychotic and/or transient mental disorders
 Mental Disorders 1.12 1.04 – 1.2 0.00254 836 8385 all phecode
291.1
Transient mental disorders due to conditions
Transient mental disorders due to conditions classified elsewhere
 Mental Disorders 0.989 0.826 – 1.19 0.909 132 1320 all phecode
291.4
Specific nonpsychotic mental disorders due to
Specific nonpsychotic mental disorders due to brain damage
 Mental Disorders 1.04 0.918 – 1.17 0.571 286 2867 all phecode
291.8 Alteration of consciousness Mental Disorders 1.21 1.1 – 1.34 8.74e-05 436 4376 all phecode
292 Neurological disorders Mental Disorders 1.13 1.1 – 1.16 7.48e-16 4621 46260 all phecode
292.1 Aphasia/speech disturbance Mental Disorders 1.2 1.14 – 1.27 4.94e-12 1504 15074 all phecode
292.2 Mild cognitive impairment Mental Disorders 1.04 0.893 – 1.2 0.644 190 1907 all phecode
292.3 Memory loss Mental Disorders 1.04 0.963 – 1.12 0.318 696 6978 all phecode
292.4 Altered mental status Mental Disorders 1.13 1.08 – 1.18 3.1e-08 2181 21827 all phecode
292.6 Hallucinations Mental Disorders 1.17 1.05 – 1.32 0.00624 307 3073 all phecode
293 Symptoms involving head and neck Mental Disorders 1.06 1.02 – 1.11 0.00609 2078 20779 all phecode
293.1
Swelling, mass, or lump in head and neck
Swelling, mass, or lump in head and neck [Space-occupying lesion, intracranial NOS]
 Mental Disorders 1.08 1.01 – 1.16 0.0233 901 9010 all phecode
295 Schizophrenia and other psychotic disorders Mental Disorders 1.08 1 – 1.16 0.0405 841 8446 all phecode
295.1 Schizophrenia Mental Disorders 1.05 0.964 – 1.15 0.256 574 5766 all phecode
295.2 Paranoid disorders Mental Disorders 1.15 0.987 – 1.35 0.0725 178 1780 all phecode
295.3 Psychosis Mental Disorders 1.05 0.898 – 1.22 0.552 169 1710 all phecode
296 Mood disorders Mental Disorders 1.15 1.13 – 1.17 1.79e-47 12372 123822 all phecode
296.1 Bipolar Mental Disorders 1 0.939 – 1.07 0.975 1059 10599 all phecode
296.2 Depression Mental Disorders 1.16 1.14 – 1.18 4.41e-53 11737 117469 all phecode
296.22 Major depressive disorder Mental Disorders 1.16 1.04 – 1.29 0.00612 361 3604 all phecode
297.2 Suicide or self-inflicted injury Mental Disorders 1.14 1.01 – 1.28 0.0272 311 3070 all phecode
300 Anxiety disorders Mental Disorders 1.13 1.1 – 1.15 1.17e-20 6844 68484 all phecode
300.1 Anxiety disorder Mental Disorders 1.12 1.09 – 1.15 1.02e-18 6324 63282 all phecode
300.11 Generalized anxiety disorder Mental Disorders 1.05 0.89 – 1.24 0.551 149 1499 all phecode
300.12 Agorophobia, social phobia, and panic disorder Mental Disorders 1.1 1.02 – 1.19 0.0149 707 7065 all phecode
300.13 Phobia Mental Disorders 1.15 1.05 – 1.26 0.00281 501 5013 all phecode
300.3 Obsessive-compulsive disorders Mental Disorders 1.21 1.02 – 1.43 0.0306 140 1407 all phecode
300.4 Dysthymic disorder Mental Disorders 1.41 1.08 – 1.83 0.0102 53 530 all phecode
300.8 Acute reaction to stress Mental Disorders 1.36 1.13 – 1.63 0.00106 124 1238 all phecode
300.9 Posttraumatic stress disorder Mental Disorders 1.21 0.991 – 1.47 0.0609 113 1129 all phecode
301 Personality disorders Mental Disorders 1.28 1.15 – 1.43 8.34e-06 334 3338 all phecode
301.2 Antisocial/borderline personality disorder Mental Disorders 1.3 1.08 – 1.55 0.0046 119 1186 all phecode
302 Sexual and gender identity disorders Mental Disorders 1.38 1.22 – 1.55 1.66e-07 283 2845 all phecode
303 Psychogenic and somatoform disorders Mental Disorders 0.994 0.904 – 1.09 0.897 467 4679 all phecode
303.3 Psychogenic disorder Mental Disorders 0.972 0.869 – 1.09 0.619 350 3510 all phecode
303.4 Somatoform disorder Mental Disorders 1.18 0.986 – 1.41 0.0705 123 1229 all phecode
304 Adjustment reaction Mental Disorders 1.15 1.02 – 1.29 0.0201 293 2936 all phecode
305.2 Eating disorder Mental Disorders 1.12 0.903 – 1.4 0.296 90 900 all phecode
306 Other mental disorder Mental Disorders 1.19 1.17 – 1.2 9.04e-163 28056 230087 all phecode
306.9 Tension headache Mental Disorders 1.21 1.08 – 1.36 0.00146 315 3148 all phecode
313 Pervasive developmental disorders Mental Disorders 1 0.799 – 1.26 0.983 76 770 all phecode
313.3 Autism Mental Disorders 0.969 0.749 – 1.25 0.813 53 539 all phecode
315 Develomental delays and disorders Mental Disorders 1.21 1.09 – 1.35 0.000497 351 3517 all phecode
315.1 Learning disorder Mental Disorders 1.28 1.09 – 1.51 0.0031 161 1610 all phecode
315.2 Speech and language disorder Mental Disorders 1.15 0.93 – 1.43 0.193 88 880 all phecode
316 Substance addiction and disorders Mental Disorders 1.14 1.11 – 1.17 3.72e-20 5313 53131 all phecode
316.1 Polyneuropathy due to drugs Mental Disorders 1.25 0.98 – 1.6 0.0725 60 599 all phecode
317 Alcohol-related disorders Mental Disorders 1.11 1.09 – 1.14 8.48e-32 12696 126892 all phecode
317.1 Alcoholism Mental Disorders 1.11 1.09 – 1.13 6.2e-21 8890 88923 all phecode
317.11 Alcoholic liver damage Mental Disorders 1.28 1.2 – 1.38 2.82e-12 838 8392 all phecode
318 Tobacco use disorder Mental Disorders 1.19 1.17 – 1.21 9.72e-120 19359 185465 all phecode
320 Meningitis Neurological 1.12 1.02 – 1.24 0.0213 444 4447 all phecode
323 Encephalitis Neurological 0.997 0.893 – 1.11 0.957 342 3422 all phecode
323.2 Acute (transverse) myelitis Neurological 0.857 0.675 – 1.09 0.206 74 739 all phecode
324 Other CNS infection and poliomyelitis Neurological 1.11 0.99 – 1.25 0.0731 292 2916 all phecode
327 Sleep disorders Neurological 1.16 1.1 – 1.23 6.01e-07 1164 11659 all phecode
327.3 Sleep apnea Neurological 1.33 1.29 – 1.37 3.29e-75 4428 44318 all phecode
327.4 Insomnia Neurological 1.09 0.933 – 1.28 0.268 163 1660 all phecode
327.41 Organic or persistent insomnia Neurological 1.08 0.908 – 1.29 0.379 136 1390 all phecode
331 Other cerebral degenerations Neurological 1.11 1.05 – 1.18 0.000366 1142 11416 all phecode
331.1 Hydrocephalus Neurological 1.05 0.959 – 1.15 0.297 502 5014 all phecode
331.9 Cerebral degeneration, unspecified Neurological 1.18 1.07 – 1.3 0.000598 430 4298 all phecode
332 Parkinson's disease Neurological 0.999 0.94 – 1.06 0.968 1126 11254 all phecode
333
Extrapyramidal disease and abnormal movement
Extrapyramidal disease and abnormal movement disorders
 Neurological 1.14 1.07 – 1.22 0.000124 894 8954 all phecode
333.1 Essential tremor Neurological 1.17 1.02 – 1.35 0.0249 216 2157 all phecode
333.2 Myoclonus Neurological 1.4 1.14 – 1.71 0.0012 96 958 all phecode
333.4 Torsion dystonia Neurological 1.12 0.987 – 1.28 0.0787 253 2528 all phecode
334 Degenerative disease of the spinal cord Neurological 1.15 1.1 – 1.21 9.94e-09 1812 18130 all phecode
334.1 Spinocerebellar disease Neurological 1.13 0.933 – 1.37 0.211 117 1169 all phecode
334.2 Anterior horn cell disease Neurological 0.999 0.877 – 1.14 0.994 245 2446 all phecode
335 Multiple sclerosis Neurological 0.979 0.926 – 1.04 0.472 1340 13385 all phecode
337 Disorders of the autonomic nervous system Neurological 1.23 1.09 – 1.4 0.00105 266 2668 all phecode
337.1 Peripheral autonomic neuropathy Neurological 1.06 0.831 – 1.36 0.626 72 719 all phecode
338 Pain Neurological 1.2 1.12 – 1.3 8.84e-07 768 7692 all phecode
338.1 Acute pain Neurological 1.25 1.13 – 1.39 3.02e-05 394 3937 all phecode
338.2 Chronic pain Neurological 1.19 1.07 – 1.32 0.00112 380 3817 all phecode
339 Other headache syndromes Neurological 1.14 1.11 – 1.17 9.01e-29 7819 78241 all phecode
340 Migraine Neurological 1.05 1.01 – 1.1 0.00697 2860 28602 all phecode
340.1 Migrain with aura Neurological 0.991 0.861 – 1.14 0.896 212 2117 all phecode
341
Other demyelinating diseases of central nervous
Other demyelinating diseases of central nervous system
 Neurological 1.03 0.906 – 1.18 0.635 252 2535 all phecode
342 Hemiplegia Neurological 1.23 1.17 – 1.29 1.04e-14 1494 14947 all phecode
343 Infantile cerebral palsy Neurological 1.08 0.912 – 1.28 0.374 145 1450 all phecode
344 Other paralytic syndromes Neurological 1.21 1.12 – 1.31 1.45e-06 658 6593 all phecode
345 Epilepsy, recurrent seizures, convulsions Neurological 1.08 1.05 – 1.11 1.68e-07 5023 50270 all phecode
345.1 Epilepsy Neurological 1.1 1.03 – 1.18 0.00694 866 8661 all phecode
345.11 Generalized convulsive epilepsy Neurological 1.18 1.07 – 1.3 0.000846 439 4385 all phecode
345.12 Partial epilepsy Neurological 1.02 0.901 – 1.15 0.775 277 2776 all phecode
345.3 Convulsions Neurological 1.06 1.02 – 1.11 0.00484 2235 22339 all phecode
346.1
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of skull and head
 Neurological 1.22 1.03 – 1.43 0.021 144 1438 all phecode
348 Other conditions of brain Neurological 1.24 1.15 – 1.33 7.85e-09 778 7808 all phecode
348.2 Cerebral edema and compression of brain Neurological 1.29 1.14 – 1.46 6.86e-05 268 2678 all phecode
348.4 Cerebral cysts Neurological 1.12 0.934 – 1.33 0.228 133 1350 all phecode
348.7 Coma Neurological 1.09 0.981 – 1.22 0.107 358 3596 all phecode
348.8 Encephalopathy, not elsewhere classified Neurological 1.26 1.11 – 1.43 0.000325 249 2504 all phecode
348.9 Other conditions of brain, NOS Neurological 1.11 1 – 1.24 0.0457 390 3899 all phecode
349
Other and unspecified disorders of the nervous
Other and unspecified disorders of the nervous system
 Neurological 1.08 0.969 – 1.21 0.161 342 3414 all phecode
350 Abnormal movement Neurological 1.15 1.11 – 1.2 1.78e-12 2671 26722 all phecode
350.1 Abnormal involuntary movements Neurological 1.13 1.06 – 1.21 0.000266 887 8852 all phecode
350.2 Abnormality of gait Neurological 1.15 1.09 – 1.21 6.22e-08 1596 15969 all phecode
350.3 Lack of coordination Neurological 1.25 1.12 – 1.39 3.72e-05 363 3638 all phecode
350.6 Disturbances of sensation of smell and taste Neurological 1.16 0.882 – 1.52 0.288 54 540 all phecode
351 Other peripheral nerve disorders Neurological 1.18 1.16 – 1.2 3.24e-68 12420 124321 all phecode
352 Disorders of other cranial nerves Neurological 1.21 1.14 – 1.27 4.12e-11 1370 13706 all phecode
352.1 Trigeminal nerve disorders [CN5] Neurological 1.16 1.05 – 1.27 0.00273 463 4638 all phecode
352.2 Facial nerve disorders [CN7] Neurological 1.24 1.16 – 1.33 1.25e-09 880 8795 all phecode
353 Nerve root and plexus disorders Neurological 1.19 1.12 – 1.27 6.69e-09 1131 11319 all phecode
353.1 Nerve plexus lesions Neurological 1.12 0.92 – 1.35 0.264 114 1138 all phecode
353.2 Nerve root lesions Neurological 1.41 1.07 – 1.85 0.0131 57 570 all phecode
356 Hereditary and idiopathic peripheral neuropathy Neurological 0.988 0.835 – 1.17 0.887 152 1520 all phecode
357 Inflammatory and toxic neuropathy Neurological 1.33 1.26 – 1.41 4.37e-25 1361 13648 all phecode
358 Myoneural disorders Neurological 1.11 0.961 – 1.27 0.159 211 2109 all phecode
358.1 Myasthenia gravis Neurological 1.14 0.983 – 1.32 0.0834 192 1919 all phecode
359 Muscular dystrophies and other myopathies Neurological 1.29 1.17 – 1.41 1.01e-07 465 4646 all phecode
359.1 Muscular dystrophies Neurological 1.13 0.944 – 1.36 0.182 122 1219 all phecode
359.2 Myopathy Neurological 1.33 1.2 – 1.48 8.15e-08 360 3597 all phecode
360 Disorders of the globe Sense Organs 1.08 0.962 – 1.2 0.199 337 3367 all phecode
360.2 Progressive myopia Sense Organs 1.04 0.914 – 1.18 0.552 251 2508 all phecode
361 Retinal detachments and defects Sense Organs 0.997 0.962 – 1.03 0.856 3246 32453 all phecode
361.1 Retinal detachment with retinal defect Sense Organs 0.997 0.944 – 1.05 0.928 1389 13884 all phecode
361.2 Retinoschisis and retinal cysts Sense Organs 1.04 0.82 – 1.33 0.73 68 680 all phecode
362 Other retinal disorders Sense Organs 1.15 1.11 – 1.18 2.72e-16 3836 38370 all phecode
362.2
Degeneration of macula and posterior pole of
Degeneration of macula and posterior pole of retina
 Sense Organs 1.09 1.04 – 1.13 0.00018 2182 21813 all phecode
362.29 Macular degeneration (senile) of retina NOS Sense Organs 1.09 1.04 – 1.13 0.000188 2179 21783 all phecode
362.3 Other nondiabetic retinopathy Sense Organs 1.38 1.18 – 1.62 7.29e-05 161 1609 all phecode
362.31 Separation of retinal layers Sense Organs 1.14 0.932 – 1.4 0.201 99 990 all phecode
362.4 Retinal vascular changes and abnomalities Sense Organs 1.21 1.13 – 1.29 5.09e-08 848 8477 all phecode
362.6 Peripheral retinal degenerations Sense Organs 0.936 0.807 – 1.09 0.387 182 1827 all phecode
362.7 Hereditary retinal dystrophies Sense Organs 1.09 0.866 – 1.36 0.473 82 812 all phecode
362.8 Retinal hemorrhage/ischemia Sense Organs 1.2 1 – 1.44 0.0505 116 1159 all phecode
363
Chorioretinal inflammations, scars, and other
Chorioretinal inflammations, scars, and other disorders of choroid
 Sense Organs 1 0.858 – 1.18 0.955 170 1699 all phecode
363.3 Chorioretinal scars Sense Organs 1.07 0.839 – 1.36 0.588 69 690 all phecode
364 Corneal opacity and other disorders of cornea Sense Organs 1.02 0.94 – 1.11 0.628 647 6485 all phecode
364.1 Corneal opacity Sense Organs 1.08 0.875 – 1.33 0.474 90 910 all phecode
364.2 Corneal edema Sense Organs 1.02 0.818 – 1.28 0.835 79 800 all phecode
364.4 Corneal degenerations Sense Organs 1.17 1.01 – 1.36 0.0354 201 2017 all phecode
364.41 Keratoconus Sense Organs 1.04 0.832 – 1.31 0.721 86 869 all phecode
364.5 Corneal dystrophy Sense Organs 0.882 0.764 – 1.02 0.0859 211 2109 all phecode
364.9 Cornea replaced by transplant Sense Organs 0.945 0.773 – 1.15 0.578 100 1000 all phecode
365 Glaucoma Sense Organs 1.08 1.04 – 1.11 3.04e-06 4408 44136 all phecode
365.1 Open-angle glaucoma Sense Organs 1.07 1.01 – 1.14 0.0245 1032 10346 all phecode
365.11 Primary open angle glaucoma Sense Organs 1.07 1.01 – 1.14 0.0255 1026 10287 all phecode
365.2 Primary angle-closure glaucoma Sense Organs 0.968 0.897 – 1.05 0.41 698 6996 all phecode
366 Cataract Sense Organs 1.1 1.09 – 1.12 1.65e-39 19926 168711 all phecode
366.1 Nonsenile Cataract Sense Organs 1.08 0.846 – 1.38 0.54 69 700 all phecode
366.2 Senile cataract Sense Organs 1.11 1.09 – 1.14 1.1e-20 8231 81909 all phecode
366.3 Traumatic cataract Sense Organs 1.02 0.836 – 1.24 0.855 102 1019 all phecode
367
Disorders of refraction and accommodation
Disorders of refraction and accommodation; blindness and low vision
 Sense Organs 1.06 1.02 – 1.11 0.00328 2408 24092 all phecode
367.1 Myopia Sense Organs 1.03 0.977 – 1.1 0.247 1251 12519 all phecode
367.2 Astigmatism Sense Organs 1.02 0.872 – 1.19 0.831 190 1899 all phecode
367.8 Hypermetropia Sense Organs 0.961 0.843 – 1.1 0.559 253 2530 all phecode
367.9 Blindness and low vision Sense Organs 1.2 1.11 – 1.29 3.15e-06 719 7198 all phecode
368 Visual disturbances Sense Organs 1.12 1.08 – 1.16 3.97e-09 2962 29648 all phecode
368.1 Amblyopia Sense Organs 1.06 0.968 – 1.15 0.217 532 5322 all phecode
368.2 Diplopia and disorders of binocular vision Sense Organs 1.15 1.06 – 1.24 0.000447 727 7288 all phecode
368.3 Anisometropia Sense Organs 1.07 0.91 – 1.26 0.402 154 1548 all phecode
368.4 Visual field defects Sense Organs 1.12 0.999 – 1.25 0.0529 333 3327 all phecode
368.9 Subjective visual disturbances Sense Organs 1.15 1.06 – 1.25 0.000847 612 6115 all phecode
369 Infection of the eye Sense Organs 0.998 0.915 – 1.09 0.962 553 5544 all phecode
369.2 Eye infection, viral Sense Organs 0.919 0.769 – 1.1 0.353 125 1257 all phecode
369.5 Conjunctivitis, infectious Sense Organs 0.976 0.848 – 1.12 0.73 213 2128 all phecode
370 Keratitis Sense Organs 1 0.888 – 1.13 0.96 286 2855 all phecode
370.1 Corneal ulcer Sense Organs 0.931 0.785 – 1.1 0.409 141 1408 all phecode
371 Inflammation of the eye Sense Organs 1.01 0.976 – 1.05 0.484 3045 30480 all phecode
371.1 Uveitis, noninfectious or NOS Sense Organs 1.03 0.939 – 1.13 0.525 482 4821 all phecode
371.3 Inflammation of eyelids Sense Organs 0.997 0.956 – 1.04 0.904 2353 23555 all phecode
372 Disorders of conjunctiva Sense Organs 1.05 0.974 – 1.13 0.203 760 7602 all phecode
374 Other disorders of eyelids Sense Organs 1.09 1.06 – 1.12 1.19e-09 5680 56807 all phecode
374.1 Ectropion or entropion Sense Organs 1.12 1.05 – 1.19 0.000372 1063 10645 all phecode
374.3 Ptosis of eyelid Sense Organs 1.09 1.04 – 1.14 0.000547 1825 18232 all phecode
375 Disorders of lacrimal system Sense Organs 1.08 1.03 – 1.12 0.000943 2204 22031 all phecode
375.2 Epiphora Sense Organs 1.05 0.982 – 1.12 0.156 898 8969 all phecode
376 Disorders of the orbit Sense Organs 0.858 0.692 – 1.07 0.166 86 859 all phecode
377 Disorders of optic nerve and visual pathways Sense Organs 1.19 1.06 – 1.32 0.00201 361 3618 all phecode
377.1 Optic atrophy Sense Organs 1.28 0.977 – 1.68 0.0733 56 570 all phecode
377.3 Optic neuritis/neuropathy Sense Organs 1.17 0.969 – 1.4 0.105 125 1249 all phecode
378
Strabismus and other disorders of binocular eye
Strabismus and other disorders of binocular eye movements
 Sense Organs 1.06 1.01 – 1.12 0.0236 1410 14116 all phecode
378.1 Strabismus (not specified as paralytic) Sense Organs 1.04 0.972 – 1.11 0.248 909 9082 all phecode
378.2 Nystagmus and other irregular eye movements Sense Organs 1.16 1.01 – 1.33 0.0341 213 2138 all phecode
378.5 Paralytic strabismus Sense Organs 1.08 0.951 – 1.22 0.239 275 2755 all phecode
379 Other disorders of eye Sense Organs 1.12 1.08 – 1.15 1.4e-10 3703 37063 all phecode
379.2 Disorders of vitreous body Sense Organs 1.15 1.09 – 1.21 5.77e-07 1367 13665 all phecode
379.3 Aphakia and other disorders of lens Sense Organs 1.13 1.08 – 1.18 6.05e-07 1813 18134 all phecode
379.4 Anomalies of pupillary function Sense Organs 1.14 0.888 – 1.46 0.303 71 710 all phecode
379.5 Disorders of iris and ciliary body Sense Organs 0.973 0.881 – 1.08 0.594 400 4028 all phecode
379.9 Pain, swelling or discharge of eye Sense Organs 1.1 0.947 – 1.29 0.207 169 1690 all phecode
380 Disorders of external ear Sense Organs 1.06 0.983 – 1.15 0.125 642 6413 all phecode
380.1 Otitis externa Sense Organs 1.23 1.12 – 1.34 5.14e-06 509 5107 all phecode
380.4 Impacted cerumen Sense Organs 1.11 0.998 – 1.24 0.054 362 3614 all phecode
381 Otitis media and Eustachian tube disorders Sense Organs 1.15 1.1 – 1.2 1.44e-09 2150 21493 all phecode
381.1 Otitis media Sense Organs 1.17 1.11 – 1.22 5.5e-10 1767 17668 all phecode
381.11 Suppurative and unspecified otitis media Sense Organs 1.18 1.1 – 1.27 1.82e-06 852 8524 all phecode
381.2 Eustachian tube disorders Sense Organs 1.06 0.914 – 1.23 0.449 193 1929 all phecode
381.3 Mastoiditis & related conditions Sense Organs 1.21 1.03 – 1.41 0.0174 171 1709 all phecode
381.9 Otorrhea Sense Organs 1.11 0.979 – 1.25 0.105 281 2807 all phecode
382 Otalgia Sense Organs 1.04 0.922 – 1.17 0.545 308 3084 all phecode
383 Otosclerosis Sense Organs 0.895 0.796 – 1.01 0.0651 309 3090 all phecode
384 Other disorders of tympanic membrane Sense Organs 1.17 1.11 – 1.24 3.58e-08 1299 12991 all phecode
384.4 Perforation of tympanic membrane Sense Organs 1.19 1.12 – 1.27 6.79e-08 1043 10432 all phecode
385 Other disorders of middle ear and mastoid Sense Organs 1.17 1.09 – 1.26 2.85e-05 783 7837 all phecode
385.3 Cholesteatoma Sense Organs 1.15 1.06 – 1.25 0.000709 607 6078 all phecode
385.5
Tympanosclerosis and middle ear disease related
Tympanosclerosis and middle ear disease related to otitis media
 Sense Organs 1.17 1.03 – 1.34 0.0178 241 2409 all phecode
386
Vertiginous syndromes and other disorders of
Vertiginous syndromes and other disorders of vestibular system
 Sense Organs 1.08 1.03 – 1.14 0.0012 1736 17373 all phecode
386.1 Meniere's disease Sense Organs 1.07 0.982 – 1.16 0.125 576 5768 all phecode
386.2 Peripheral or central vertigo Sense Organs 1.05 0.948 – 1.17 0.336 377 3763 all phecode
386.3 Labyrinthitis Sense Organs 1.12 1.04 – 1.21 0.00263 765 7664 all phecode
386.9
Dizziness and giddiness (Light-headedness and
Dizziness and giddiness (Light-headedness and vertigo)
 Sense Organs 1.14 1.1 – 1.17 4.89e-17 4582 45806 all phecode
388 Other disorders of ear Sense Organs 1.01 0.878 – 1.17 0.853 202 2017 all phecode
389 Hearing loss Sense Organs 1.13 1.09 – 1.16 1.22e-13 4188 41944 all phecode
389.1 Sensorineural hearing loss Sense Organs 1.17 1.06 – 1.29 0.00149 456 4553 all phecode
389.2 Conductive hearing loss Sense Organs 1.16 1.05 – 1.27 0.0028 450 4497 all phecode
389.4 Tinnitus Sense Organs 1.11 1.01 – 1.21 0.0277 513 5134 all phecode
394 Rheumatic disease of the heart valves Circulatory System 1.11 1.08 – 1.14 1.54e-12 4899 48974 all phecode
394.2 Mitral valve disease Circulatory System 1.09 1.05 – 1.13 1.13e-05 2993 29922 all phecode
394.3 Aortic valve disease Circulatory System 1.14 1.08 – 1.21 5.11e-06 1282 12814 all phecode
394.7 Disease of tricuspid valve Circulatory System 1.13 1.07 – 1.21 7.15e-05 1058 10566 all phecode
395 Heart valve disorders Circulatory System 1.12 1.08 – 1.15 2.85e-12 4223 42219 all phecode
395.1 Nonrheumatic mitral valve disorders Circulatory System 1.09 1.05 – 1.14 3.21e-06 2891 28900 all phecode
395.2 Nonrheumatic aortic valve disorders Circulatory System 1.19 1.06 – 1.35 0.00381 276 2766 all phecode
395.3 Nonrheumatic tricuspid valve disorders Circulatory System 1.12 0.916 – 1.36 0.276 105 1039 all phecode
395.4 Nonrheumatic pulmonary valve disorders Circulatory System 1.14 0.928 – 1.39 0.215 97 970 all phecode
395.6 Heart valve replaced Circulatory System 1.15 1.09 – 1.21 8.23e-08 1495 14942 all phecode
396 Abnormal heart sounds Circulatory System 1.13 1.06 – 1.2 0.000139 1048 10468 all phecode
401 Hypertension Circulatory System 1.33 1.32 – 1.35 6.43e-953 73956 266957 all phecode
401.1 Essential hypertension Circulatory System 1.33 1.32 – 1.35 2.69e-952 73731 266739 all phecode
401.2 Hypertensive heart and/or renal disease Circulatory System 1.56 1.48 – 1.63 3.5e-74 1898 19031 all phecode
401.21 Hypertensive heart disease Circulatory System 1.45 1.3 – 1.61 1.32e-11 370 3699 all phecode
401.22 Hypertensive chronic kidney disease Circulatory System 1.58 1.5 – 1.66 2.43e-64 1543 15483 all phecode
401.3 Other hypertensive complications Circulatory System 1.34 1.13 – 1.6 0.00102 144 1438 all phecode
402
Elevated blood pressure reading without
Elevated blood pressure reading without diagnosis of hypertension
 Circulatory System 1.3 1.23 – 1.38 8.06e-22 1479 14786 all phecode
411 Ischemic Heart Disease Circulatory System 1.28 1.26 – 1.29 1.92e-351 31245 210714 all phecode
411.1 Unstable angina (intermediate coronary syndrome) Circulatory System 1.37 1.33 – 1.41 1.22e-105 5152 51498 all phecode
411.2 Myocardial infarction Circulatory System 1.32 1.29 – 1.34 5.6e-183 11950 112699 all phecode
411.3 Angina pectoris Circulatory System 1.33 1.31 – 1.35 5.91e-261 15888 143745 all phecode
411.4 Coronary atherosclerosis Circulatory System 1.29 1.27 – 1.31 3.86e-256 20171 154621 all phecode
411.41 Aneurysm and dissection of heart Circulatory System 1.04 0.962 – 1.12 0.322 700 6997 all phecode
411.8
Other chronic ischemic heart disease
Other chronic ischemic heart disease, unspecified
 Circulatory System 1.36 1.33 – 1.38 7.18e-283 15290 131798 all phecode
411.9
Other acute and subacute forms of ischemic
Other acute and subacute forms of ischemic heart disease
 Circulatory System 1.36 1.28 – 1.44 4.57e-25 1218 12166 all phecode
414 Other forms of chronic heart disease Circulatory System 1.32 1.26 – 1.39 4.5e-31 1823 18228 all phecode
414.2 ASCVD Circulatory System 1.32 1.05 – 1.67 0.0163 72 719 all phecode
415 Pulmonary heart disease Circulatory System 1.09 1.05 – 1.12 9.98e-08 4476 44810 all phecode
415.11 Pulmonary embolism and infarction, acute Circulatory System 0.938 0.744 – 1.18 0.587 75 750 all phecode
415.2 Chronic pulmonary heart disease Circulatory System 1.17 1.08 – 1.27 0.000176 601 6002 all phecode
415.21 Primary pulmonary hypertension Circulatory System 1.17 1.07 – 1.29 0.000851 448 4475 all phecode
416 Cardiomegaly Circulatory System 1.25 1.2 – 1.3 1.86e-28 2680 26793 all phecode
418 Nonspecific chest pain Circulatory System 1.17 1.16 – 1.19 9.67e-150 28599 270106 all phecode
418.1 Precordial pain Circulatory System 1.22 1.18 – 1.26 2.39e-30 3551 35541 all phecode
420 Carditis Circulatory System 1.08 1.03 – 1.12 0.00119 2106 21053 all phecode
420.1 Myocarditis Circulatory System 0.969 0.805 – 1.17 0.742 127 1267 all phecode
420.2 Pericarditis Circulatory System 1.07 1.01 – 1.13 0.0253 1338 13371 all phecode
420.21 Acute pericarditis Circulatory System 1.15 1.01 – 1.32 0.0402 223 2227 all phecode
420.22 Chronic pericarditis Circulatory System 1.08 0.898 – 1.3 0.419 113 1129 all phecode
420.3 Endocarditis Circulatory System 1.13 1.05 – 1.22 0.00128 719 7194 all phecode
425 Cardiomyopathy Circulatory System 1.2 1.13 – 1.27 8.13e-10 1271 12699 all phecode
425.1 Primary/intrinsic cardiomyopathies Circulatory System 1.2 1.14 – 1.28 3.29e-10 1236 12349 all phecode
425.11 Hypertrophic obstructive cardiomyopathy Circulatory System 1.14 0.949 – 1.36 0.165 133 1329 all phecode
425.12 Other hypertrophic cardiomyopathy Circulatory System 1.04 0.886 – 1.21 0.658 163 1629 all phecode
425.8 Other cardiomyopathy Circulatory System 1.05 0.809 – 1.35 0.731 60 600 all phecode
426 Cardiac conduction disorders Circulatory System 1.19 1.16 – 1.22 1.43e-44 6910 69146 all phecode
426.2 Atrioventricular [AV] block Circulatory System 1.19 1.14 – 1.24 9.11e-15 2114 21162 all phecode
426.21 First degree AV block Circulatory System 1.25 1.17 – 1.34 6.81e-12 986 9867 all phecode
426.23 Second degree AV block Circulatory System 1.14 1.04 – 1.25 0.0067 452 4515 all phecode
426.24 Atrioventricular block, complete Circulatory System 1.2 1.1 – 1.3 3.06e-05 587 5868 all phecode
426.25 Other heart block Circulatory System 1.01 0.852 – 1.21 0.876 131 1318 all phecode
426.3 Bundle branch block Circulatory System 1.21 1.16 – 1.25 2.18e-25 3336 33359 all phecode
426.31 Right bundle branch block Circulatory System 1.16 1.1 – 1.22 3.4e-08 1494 14933 all phecode
426.32 Left bundle branch block Circulatory System 1.24 1.18 – 1.31 1.67e-18 1750 17503 all phecode
426.4 Anomalous atrioventricular excitation Circulatory System 1.06 0.922 – 1.21 0.434 233 2328 all phecode
426.8 Other cardiac conduction disorders Circulatory System 1.17 0.908 – 1.5 0.227 60 600 all phecode
426.9 Cardiac pacemaker/device in situ Circulatory System 1.24 1.19 – 1.29 1.92e-25 2475 24774 all phecode
426.91 Cardiac pacemaker in situ Circulatory System 1.23 1.18 – 1.28 9.82e-22 2274 22762 all phecode
427 Cardiac dysrhythmias Circulatory System 1.11 1.1 – 1.13 1.11e-56 24207 206016 all phecode
427.1 Paroxysmal tachycardia, unspecified Circulatory System 1.1 1.07 – 1.15 6.4e-08 3199 32017 all phecode
427.11 Paroxysmal supraventricular tachycardia Circulatory System 1.08 1.03 – 1.13 0.000384 2344 23474 all phecode
427.12 Paroxysmal ventricular tachycardia Circulatory System 1.2 1.13 – 1.28 4.3e-08 936 9365 all phecode
427.2 Atrial fibrillation and flutter Circulatory System 1.12 1.1 – 1.14 3.99e-41 14628 133501 all phecode
427.3 Other specified cardiac dysrhythmias Circulatory System 1.14 1.1 – 1.18 2.13e-12 3228 32281 all phecode
427.4 Cardiac arrest and ventricular fibrillation Circulatory System 1.18 1.11 – 1.25 6.23e-08 1193 11915 all phecode
427.41 Ventricular fibrillation and flutter Circulatory System 1.19 1.06 – 1.33 0.00232 344 3437 all phecode
427.42 Cardiac arrest Circulatory System 1.18 1.11 – 1.26 2.8e-07 990 9890 all phecode
427.5 Arrhythmia (cardiac) NOS Circulatory System 1.02 0.956 – 1.09 0.521 952 9541 all phecode
427.6 Premature beats Circulatory System 1.11 1.02 – 1.21 0.0215 535 5358 all phecode
427.61 Supraventricular premature beats Circulatory System 1.09 0.905 – 1.31 0.367 117 1168 all phecode
427.7 Tachycardia NOS Circulatory System 1.16 1.11 – 1.21 8.34e-11 2185 21865 all phecode
427.8 Sinoatrial node dysfunction (Bradycardia) Circulatory System 1.11 0.999 – 1.22 0.0515 402 4029 all phecode
427.9 Palpitations Circulatory System 1.08 1.04 – 1.11 1.24e-05 3811 38105 all phecode
428 Congestive heart failure; nonhypertensive Circulatory System 1.31 1.28 – 1.35 1.04e-88 5605 56018 all phecode
428.1 Congestive heart failure (CHF) NOS Circulatory System 1.44 1.38 – 1.51 4.58e-60 2111 21108 all phecode
428.2 Heart failure NOS Circulatory System 1.29 1.25 – 1.33 2.73e-62 4455 44524 all phecode
429
Ill-defined descriptions and complications of
Ill-defined descriptions and complications of heart disease
 Circulatory System 1.12 1.04 – 1.21 0.0043 716 7168 all phecode
429.1 Heart transplant/surgery Circulatory System 1.22 0.951 – 1.56 0.12 64 639 all phecode
429.2 Abnormal function study of cardiovascular system Circulatory System 1.09 0.997 – 1.19 0.0585 522 5211 all phecode
429.3 Symptoms involving cardiovascular system Circulatory System 1.21 1.05 – 1.4 0.00991 196 1978 all phecode
430 Intracranial hemorrhage Circulatory System 1.08 1.03 – 1.13 0.00191 1883 18825 all phecode
430.1 Subarachnoid hemorrhage Circulatory System 1.02 0.952 – 1.09 0.568 836 8353 all phecode
430.2 Intracerebral hemorrhage Circulatory System 1.09 1.02 – 1.18 0.0166 765 7656 all phecode
430.3 Subdural hemorrhage Circulatory System 1.04 0.921 – 1.18 0.51 267 2667 all phecode
433 Cerebrovascular disease Circulatory System 1.18 1.16 – 1.21 1.74e-51 8749 87456 all phecode
433.1 Occlusion and stenosis of precerebral arteries Circulatory System 1.28 1.21 – 1.35 8.47e-17 1185 11825 all phecode
433.12 Cerebral atherosclerosis Circulatory System 1.27 1.11 – 1.45 0.000376 227 2267 all phecode
433.2 Occlusion of cerebral arteries Circulatory System 1.21 1.17 – 1.24 2.19e-32 4233 42320 all phecode
433.21
Cerebral artery occlusion, with cerebral
Cerebral artery occlusion, with cerebral infarction
 Circulatory System 1.27 1.21 – 1.34 8.35e-22 1680 16794 all phecode
433.3 Cerebral ischemia Circulatory System 1.15 1.11 – 1.19 5.19e-13 2895 28989 all phecode
433.31 Transient cerebral ischemia Circulatory System 1.16 1.11 – 1.21 6.15e-11 2135 21379 all phecode
433.5 Cerebral aneurysm Circulatory System 1.02 0.919 – 1.13 0.708 394 3939 all phecode
433.8 Late effects of cerebrovascular disease Circulatory System 1.26 1.19 – 1.33 7.53e-16 1279 12783 all phecode
440 Atherosclerosis Circulatory System 1.43 1.35 – 1.51 2.52e-38 1380 13822 all phecode
440.1 Atherosclerosis of renal artery Circulatory System 1.27 1.05 – 1.54 0.0146 113 1129 all phecode
440.2 Atherosclerosis of the extremities Circulatory System 1.54 1.44 – 1.65 1.82e-33 805 8070 all phecode
440.9 Atherosclerosis of aorta Circulatory System 1.33 1.18 – 1.51 4.18e-06 287 2867 all phecode
441 Vascular insufficiency of intestine Circulatory System 1.16 1.07 – 1.26 0.000287 614 6154 all phecode
441.1 Acute vascular insufficiency of intestine Circulatory System 1.09 0.97 – 1.23 0.145 283 2827 all phecode
442 Other aneurysm Circulatory System 1.1 1.05 – 1.15 7.62e-05 1892 18959 all phecode
442.1 Aortic aneurysm Circulatory System 1.08 1.03 – 1.14 0.00251 1458 14625 all phecode
442.11 Abdominal aortic aneurysm Circulatory System 1.14 1.07 – 1.22 6.04e-05 931 9341 all phecode
442.2 Aneurysm of iliac artery Circulatory System 1.11 0.915 – 1.34 0.298 102 1019 all phecode
442.3 Aneurysm of artery of lower extremity Circulatory System 1.29 1.11 – 1.5 0.000997 169 1696 all phecode
442.4 Arterial dissection Circulatory System 0.951 0.718 – 1.26 0.727 54 549 all phecode
442.8 Aneurysm of other specified artery Circulatory System 1.02 0.882 – 1.18 0.802 203 2028 all phecode
443 Peripheral vascular disease Circulatory System 1.39 1.35 – 1.44 3.49e-90 3921 39273 all phecode
443.1 Raynaud's syndrome Circulatory System 1.04 0.977 – 1.1 0.228 1145 11438 all phecode
443.7
Peripheral angiopathy in diseases classified
Peripheral angiopathy in diseases classified elsewhere
 Circulatory System 3.23 2.87 – 3.64 6.07e-84 384 3878 all phecode
443.8 Other specified peripheral vascular diseases Circulatory System 1.33 1.28 – 1.37 8.63e-63 3686 36906 all phecode
443.9 Peripheral vascular disease, unspecified Circulatory System 1.47 1.42 – 1.53 2.79e-83 2579 25846 all phecode
444 Arterial embolism and thrombosis Circulatory System 1.48 1.39 – 1.58 1.74e-31 922 9251 all phecode
444.1
Arterial embolism and thrombosis of lower
Arterial embolism and thrombosis of lower extremity artery
 Circulatory System 1.68 1.54 – 1.83 6.77e-33 554 5552 all phecode
446 Polyarteritis nodosa and allied conditions Circulatory System 1.14 1.06 – 1.22 0.000271 822 8226 all phecode
446.4 Wegener's granulomatosis Circulatory System 1.11 0.956 – 1.28 0.174 188 1878 all phecode
446.5 Giant cell arteritis Circulatory System 1.04 0.937 – 1.15 0.481 388 3879 all phecode
446.9 Arteritis NOS Circulatory System 1.21 1.06 – 1.37 0.0039 239 2400 all phecode
447 Other disorders of arteries and arterioles Circulatory System 1.39 1.31 – 1.46 1.94e-31 1327 13316 all phecode
447.1 Stricture of artery Circulatory System 1.51 1.41 – 1.62 2.7e-32 868 8712 all phecode
448 Disease of capillaries Circulatory System 1.04 0.879 – 1.24 0.635 142 1420 all phecode
450 Noninfectious disorders of lymphatic channels Circulatory System 1.15 1.06 – 1.24 0.000475 704 7034 all phecode
451 Phlebitis and thrombophlebitis Circulatory System 1.13 1.1 – 1.17 4.69e-14 3955 39683 all phecode
451.2
Phlebitis and thrombophlebitis of lower
Phlebitis and thrombophlebitis of lower extremities
 Circulatory System 1.13 1.1 – 1.17 2.49e-13 3683 36977 all phecode
452 Other venous embolism and thrombosis Circulatory System 1.1 1.01 – 1.2 0.0249 564 5645 all phecode
454 Varicose veins Circulatory System 1.01 0.987 – 1.03 0.514 11180 112047 all phecode
454.1 Varicose veins of lower extremity Circulatory System 0.997 0.978 – 1.02 0.774 11503 115272 all phecode
454.11 Varicose veins of lower extremity, symptomtic Circulatory System 1.04 0.956 – 1.13 0.377 624 6325 all phecode
455 Hemorrhoids Circulatory System 1.04 1.03 – 1.06 2.72e-09 23452 234585 all phecode
456 Chronic venous insufficiency [CVI] Circulatory System 1.02 0.882 – 1.19 0.756 184 1868 all phecode
457
Encounter for long-term (current) use of
Encounter for long-term (current) use of anticoagulants, antithrombotics, aspirin
 Circulatory System 0.902 0.737 – 1.1 0.315 97 967 all phecode
458 Hypotension Circulatory System 1.12 1.09 – 1.15 1.81e-17 5769 57772 all phecode
458.1 Orthostatic hypotension Circulatory System 1.21 1.14 – 1.28 1.47e-11 1335 13376 all phecode
458.2 Iatrogenic hypotension Circulatory System 1.13 0.989 – 1.29 0.0723 235 2348 all phecode
458.9 Hypotension NOS Circulatory System 1.12 1.09 – 1.16 2.63e-11 3494 35005 all phecode
459 Other disorders of circulatory system Circulatory System 1.16 1.14 – 1.18 2.42e-76 16268 160790 all phecode
459.1 Hemorrhage NOS Circulatory System 1.11 0.94 – 1.31 0.221 142 1420 all phecode
459.9 Circulatory disease NEC Circulatory System 1.16 1.15 – 1.18 5.94e-78 16103 159422 all phecode
464 Acute sinusitis Respiratory 1.17 1.01 – 1.35 0.0357 196 1957 all phecode
465
Acute upper respiratory infections of multiple
Acute upper respiratory infections of multiple or unspecified sites
 Respiratory 1.13 1.08 – 1.18 1.66e-08 2283 22827 all phecode
465.2 Acute pharyngitis Respiratory 1.13 1.06 – 1.22 0.00055 835 8348 all phecode
465.4 Acute laryngitis and tracheitis Respiratory 1.19 1.02 – 1.4 0.0272 165 1649 all phecode
470 Septal Deviations/Turbinate Hypertrophy Respiratory 1.06 1.03 – 1.09 0.000155 4654 46553 all phecode
471 Nasal polyps Respiratory 1.07 1.04 – 1.11 7.18e-05 3297 32973 all phecode
472 Chronic pharyngitis and nasopharyngitis Respiratory 1.04 0.976 – 1.12 0.212 960 9594 all phecode
473 Diseases of the larynx and vocal cords Respiratory 1.12 1.07 – 1.16 1.3e-07 2554 25548 all phecode
473.1 Chronic laryngitis Respiratory 1.07 0.884 – 1.3 0.478 104 1038 all phecode
473.3 Paralysis/spasm of vocal cords or larynx Respiratory 1.08 0.955 – 1.23 0.215 264 2647 all phecode
473.4 Voice disturbance Respiratory 1.09 1.02 – 1.16 0.00854 1080 10789 all phecode
474 Acute and chronic tonsillitis Respiratory 1.09 1.04 – 1.15 0.000327 1772 17710 all phecode
474.1 Acute tonsillitis Respiratory 1.13 1.04 – 1.24 0.00578 549 5486 all phecode
474.2 Chronic tonsillitis and adenoiditis Respiratory 1.1 1.03 – 1.17 0.00322 1122 11199 all phecode
475 Chronic sinusitis Respiratory 1.09 1.05 – 1.13 3.1e-05 2589 25882 all phecode
476 Allergic rhinitis Respiratory 1.02 0.961 – 1.09 0.456 1055 10563 all phecode
477 Epistaxis or throat hemorrhage Respiratory 1.1 1.06 – 1.15 2.07e-06 2447 24452 all phecode
478 Throat pain Respiratory 1.04 0.936 – 1.15 0.476 377 3789 all phecode
479 Other upper respiratory disease Respiratory 1.1 1.06 – 1.13 2.02e-08 4074 40737 all phecode
480 Pneumonia Respiratory 1.12 1.1 – 1.14 1.32e-29 10336 103397 all phecode
480.1 Bacterial pneumonia Respiratory 1.1 1.08 – 1.13 4.88e-15 6637 66410 all phecode
480.11 Pneumococcal pneumonia Respiratory 1.09 1.06 – 1.12 1.2e-10 5883 58863 all phecode
480.12 Pseudomonal pneumonia Respiratory 1.36 1.12 – 1.65 0.00197 93 929 all phecode
480.2 Viral pneumonia Respiratory 1.19 0.941 – 1.5 0.148 72 720 all phecode
480.3 Pneumonia due to fungus (mycoses) Respiratory 1.15 0.938 – 1.41 0.178 99 989 all phecode
480.5 Bronchopneumonia and lung abscess Respiratory 1.15 1.07 – 1.23 0.000208 794 7951 all phecode
481 Influenza Respiratory 1.04 0.931 – 1.17 0.471 328 3278 all phecode
483 Acute bronchitis and bronchiolitis Respiratory 1.31 1.14 – 1.52 0.00024 193 1930 all phecode
495 Asthma Respiratory 1.17 1.15 – 1.18 5.42e-121 25689 250406 all phecode
495.2 Asthma with exacerbation Respiratory 1.24 1.09 – 1.41 0.00111 250 2510 all phecode
496 Chronic airway obstruction Respiratory 1.23 1.2 – 1.25 3.04e-91 10424 101546 all phecode
496.1 Emphysema Respiratory 1.18 1.13 – 1.24 1.63e-11 1743 17438 all phecode
496.2 Chronic bronchitis Respiratory 1.24 1.2 – 1.29 3.08e-30 2947 29498 all phecode
496.21 Obstructive chronic bronchitis Respiratory 1.24 1.19 – 1.29 1.48e-27 2706 27081 all phecode
496.3 Bronchiectasis Respiratory 1.1 1.05 – 1.15 0.000107 1885 18859 all phecode
497 Bronchitis Respiratory 1.09 1 – 1.18 0.041 626 6267 all phecode
500 Lung disease due to external agents Respiratory 1.09 0.983 – 1.2 0.104 412 4099 all phecode
500.1 Extrinsic allergic alveolitis Respiratory 0.986 0.787 – 1.24 0.906 79 784 all phecode
500.2 Pneumoconiosis Respiratory 1.14 0.999 – 1.29 0.0517 243 2409 all phecode
501 Pneumonitis due to inhalation of food or vomitus Respiratory 1.18 1.09 – 1.27 6.46e-05 656 6557 all phecode
502 Postinflammatory pulmonary fibrosis Respiratory 1.15 1.07 – 1.23 4.57e-05 917 9193 all phecode
503 Pulmonary congestion and hypostasis Respiratory 1.38 1.26 – 1.51 3.59e-12 508 5079 all phecode
504 Other alveolar and parietoalveolar pneumonopathy Respiratory 1.23 1.1 – 1.37 0.000329 328 3280 all phecode
505 Other pulmonary inflamation or edema Respiratory 1.02 0.781 – 1.32 0.906 61 610 all phecode
506 Empyema and pneumothorax Respiratory 1.06 0.995 – 1.12 0.0726 1133 11362 all phecode
507 Pleurisy; pleural effusion Respiratory 1.11 1.09 – 1.14 3.53e-17 6419 64252 all phecode
508
Pulmonary collapse; interstitial and
Pulmonary collapse; interstitial and compensatory emphysema
 Respiratory 1.12 1.07 – 1.17 2.01e-06 1996 19947 all phecode
509 Respiratory failure, insufficiency, arrest Respiratory 1.22 1.17 – 1.27 8.18e-23 2599 26031 all phecode
509.1 Respiratory failure Respiratory 1.24 1.19 – 1.3 1.37e-21 2068 20708 all phecode
509.2 Respiratory insufficiency Respiratory 1.23 1.18 – 1.29 8.13e-18 1806 18106 all phecode
509.5 Respiratory arrest Respiratory 1.07 0.909 – 1.27 0.404 143 1429 all phecode
509.8
Dependence on respirator [Ventilator] or
Dependence on respirator [Ventilator] or supplemental oxygen
 Respiratory 1.2 1.08 – 1.33 0.000422 386 3863 all phecode
510 Other diseases of lung Respiratory 1.13 1.05 – 1.22 0.00106 755 7554 all phecode
512 Other symptoms of respiratory system Respiratory 1.18 1.15 – 1.2 2.12e-50 9031 90349 all phecode
512.1 Wheezing Respiratory 1.28 1.12 – 1.47 0.000362 220 2196 all phecode
512.2 Painful respiration Respiratory 1.22 1.06 – 1.4 0.00661 207 2075 all phecode
512.7 Shortness of breath Respiratory 1.21 1.18 – 1.25 2.86e-46 5842 58498 all phecode
512.8 Cough Respiratory 1.11 1.07 – 1.15 8.27e-08 2866 28642 all phecode
512.9 Other dyspnea Respiratory 1.15 1.07 – 1.23 6.44e-05 914 9124 all phecode
513 Respiratory abnormalities Respiratory 1.19 1.09 – 1.29 4.07e-05 611 6112 all phecode
513.3 Hypoventilation Respiratory 1.34 1.07 – 1.68 0.00988 83 830 all phecode
513.4 Hyperventilation Respiratory 1.28 1.13 – 1.44 6.75e-05 278 2778 all phecode
513.8 Disorders of diaphragm Respiratory 1.17 0.995 – 1.37 0.0579 153 1538 all phecode
514 Abnormal findings examination of lungs Respiratory 1.07 1.03 – 1.12 0.00111 2465 24673 all phecode
516 Abnormal sputum Respiratory 1.12 1.07 – 1.17 8.94e-07 2132 21335 all phecode
516.1 Hemoptysis Respiratory 1.11 1.06 – 1.16 4.23e-06 2073 20745 all phecode
519
Other diseases of respiratory system, not
Other diseases of respiratory system, not elsewhere classified
 Respiratory 1.15 1.13 – 1.18 3.73e-40 9366 93681 all phecode
519.2 Respiratory complications Respiratory 1.13 1.01 – 1.26 0.037 327 3279 all phecode
519.8 Other diseases of respiratory system, NEC Respiratory 1.16 1.13 – 1.18 1.58e-40 8853 88522 all phecode
519.9
Symptoms involving respiratory system and other
Symptoms involving respiratory system and other chest symptoms
 Respiratory 0.965 0.858 – 1.09 0.561 303 3049 all phecode
520 Disorders of tooth development Digestive 1 0.958 – 1.05 0.895 2038 20354 all phecode
520.1 Hereditary disturbances in tooth structure Digestive 0.957 0.719 – 1.27 0.766 53 530 all phecode
520.2 Disturbances in tooth eruption Digestive 1 0.962 – 1.05 0.841 2356 23539 all phecode
521 Diseases of hard tissues of teeth Digestive 1.13 1.09 – 1.18 3.18e-11 3016 30245 all phecode
521.1 Dental caries Digestive 1.14 1.1 – 1.18 6.14e-12 3026 30353 all phecode
522 Diseases of pulp and periapical tissues Digestive 1.05 1 – 1.11 0.0426 1774 17750 all phecode
522.5 Periapical abscess Digestive 1.08 1.02 – 1.15 0.0126 1172 11731 all phecode
523 Gingival and periodontal diseases Digestive 1.04 0.99 – 1.09 0.114 1681 16812 all phecode
523.1 Gingivitis Digestive 1.02 0.834 – 1.24 0.86 113 1127 all phecode
523.3 Periodontitis (acute or chronic) Digestive 1.01 0.95 – 1.07 0.753 1165 11650 all phecode
523.31 Acute periodontitis Digestive 1.01 0.933 – 1.1 0.788 666 6667 all phecode
523.32 Chronic periodontitis Digestive 1.02 0.937 – 1.12 0.622 560 5594 all phecode
524 Dentofacial anomalies, including malocclusion Digestive 1.01 0.904 – 1.13 0.836 331 3307 all phecode
524.3 Anomalies of tooth position/malocclusion Digestive 0.99 0.881 – 1.11 0.872 305 3046 all phecode
525
Other diseases of the teeth and supporting
Other diseases of the teeth and supporting structures
 Digestive 1.12 1.07 – 1.16 3.2e-08 2668 26728 all phecode
525.2 Atrophy of edentulous alveolar ridge Digestive 0.885 0.697 – 1.13 0.319 72 720 all phecode
526 Diseases of the jaws Digestive 1.06 0.988 – 1.13 0.107 928 9279 all phecode
526.1 Cysts of the jaws Digestive 1.01 0.904 – 1.14 0.806 329 3289 all phecode
526.3 Anomalies of jaw size/symmetry Digestive 0.983 0.764 – 1.27 0.897 61 610 all phecode
526.4 Temporomandibular joint disorders Digestive 1.09 0.959 – 1.24 0.185 240 2406 all phecode
526.41 Temporomandibular joint disorder, unspecified Digestive 1.11 0.973 – 1.26 0.12 233 2336 all phecode
526.5 Inflammatory conditions of jaw Digestive 0.962 0.785 – 1.18 0.71 110 1098 all phecode
526.9 Jaw disease NOS Digestive 1.11 0.971 – 1.27 0.125 233 2329 all phecode
527 Diseases of the salivary glands Digestive 1.15 1.07 – 1.25 0.000273 694 6943 all phecode
527.1 Hypertrophy of salivary gland Digestive 1.16 0.929 – 1.45 0.192 84 838 all phecode
527.2 Sialoadenitis Digestive 1.15 1.04 – 1.28 0.00871 365 3656 all phecode
527.7 Disturbance of salivary secretion Digestive 0.988 0.764 – 1.28 0.925 62 619 all phecode
527.8 Other specified diseases of the salivary glands Digestive 1.03 0.847 – 1.24 0.794 120 1200 all phecode
528
Diseases of the oral soft tissues, excluding
Diseases of the oral soft tissues, excluding lesions specific for gingiva and tongue
 Digestive 1.08 1.05 – 1.12 1.3e-06 3873 38741 all phecode
528.1 Stomatitis and mucositis Digestive 1.05 0.956 – 1.15 0.311 468 4675 all phecode
528.11 Stomatitis and mucositis (ulcerative) Digestive 1.06 0.954 – 1.17 0.29 389 3884 all phecode
528.12 Oral aphthae Digestive 1.09 0.877 – 1.36 0.434 84 840 all phecode
528.3 Cellulitis and abscess of oral soft tissues Digestive 1.1 0.943 – 1.27 0.233 179 1790 all phecode
528.4 Cysts of oral soft tissues Digestive 1.01 0.836 – 1.21 0.957 122 1219 all phecode
528.41 Cyst of the salivary gland Digestive 1.01 0.818 – 1.24 0.938 94 940 all phecode
528.5 Diseases of lips Digestive 1.02 0.942 – 1.1 0.647 681 6813 all phecode
528.6 Leukoplakia of oral mucosa Digestive 1.24 1.1 – 1.39 0.000331 308 3079 all phecode
528.7 Sialolithiasis Digestive 1.11 0.984 – 1.25 0.0912 314 3138 all phecode
529 Diseases and other conditions of the tongue Digestive 1.08 1.01 – 1.14 0.016 1232 12312 all phecode
529.1 Glossitis Digestive 1.27 1.12 – 1.42 0.000104 299 2986 all phecode
530 Diseases of esophagus Digestive 1.11 1.1 – 1.13 3.14e-77 33453 279172 all phecode
530.1 Esophagitis, GERD and related diseases Digestive 1.11 1.1 – 1.13 1.14e-74 31253 272429 all phecode
530.11 GERD Digestive 1.11 1.1 – 1.13 2.7e-54 22633 225879 all phecode
530.12 Ulcer of esophagus Digestive 1.11 1.08 – 1.14 2.27e-13 5203 52068 all phecode
530.14 Reflux esophagitis Digestive 1.1 1.08 – 1.13 2.48e-22 10444 104493 all phecode
530.2 Esophageal bleeding (varices/hemorrhage) Digestive 1.18 1.12 – 1.24 1.6e-10 1681 16808 all phecode
530.3 Stricture and stenosis of esophagus Digestive 1.05 0.999 – 1.1 0.0572 1869 18684 all phecode
530.5 Disorders of esophageal motility Digestive 1.1 1.01 – 1.19 0.0262 635 6365 all phecode
530.6 Diverticulum of esophagus, acquired Digestive 1.16 0.981 – 1.37 0.0823 153 1527 all phecode
530.7 Gastroesophageal laceration-hemorrhage syndrome Digestive 1.16 1.04 – 1.3 0.00837 341 3416 all phecode
530.9 Heartburn Digestive 1.08 1.04 – 1.13 0.000508 2087 20881 all phecode
531 Peptic ulcer (excl. esophageal) Digestive 1.16 1.13 – 1.18 2.21e-32 7103 71066 all phecode
531.1 Hemorrhage from gastrointestinal ulcer Digestive 1.11 1.02 – 1.2 0.0117 637 6374 all phecode
531.2 Gastric ulcer Digestive 1.15 1.11 – 1.19 1.05e-17 4091 40941 all phecode
531.3 Duodenal ulcer Digestive 1.19 1.15 – 1.23 2.41e-20 2999 30005 all phecode
531.4 Peptic ulcer, site unspecified Digestive 1.2 1.09 – 1.32 0.000278 427 4268 all phecode
532 Dysphagia Digestive 1.08 1.06 – 1.11 4.49e-10 6427 64329 all phecode
535 Gastritis and duodenitis Digestive 1.13 1.12 – 1.14 1.18e-85 28078 261548 all phecode
535.1 Acute gastritis Digestive 1.21 1.14 – 1.29 1.74e-10 1183 11833 all phecode
535.2 Atrophic gastritis Digestive 1.16 1.04 – 1.29 0.00627 370 3687 all phecode
535.6 Duodenitis Digestive 1.14 1.11 – 1.17 7.11e-28 7592 75928 all phecode
535.8 Other specified gastritis Digestive 1.13 1.11 – 1.16 7.72e-28 8071 80763 all phecode
535.9 Gastritis and duodenitis, NOS Digestive 1.24 1.02 – 1.49 0.0282 120 1191 all phecode
536.8
Dyspepsia and other specified disorders of
Dyspepsia and other specified disorders of function of stomach
 Digestive 1.01 0.888 – 1.14 0.928 259 2576 all phecode
537 Other disorders of stomach and duodenum Digestive 1.13 1.09 – 1.17 1.71e-12 3391 33907 all phecode
540 Appendiceal conditions Digestive 1.04 1.01 – 1.08 0.0223 3088 30890 all phecode
540.1 Appendicitis Digestive 1.04 0.998 – 1.08 0.0667 2895 28963 all phecode
540.11 Acute appendicitis Digestive 1.02 0.976 – 1.06 0.433 2601 26019 all phecode
550 Abdominal hernia Digestive 1.06 1.05 – 1.07 2.39e-32 45429 282640 all phecode
550.1 Inguinal hernia Digestive 0.953 0.937 – 0.968 7.68e-09 15794 123247 all phecode
550.2 Diaphragmatic hernia Digestive 1.11 1.09 – 1.12 3.1e-57 26494 238953 all phecode
550.3 Femoral hernia Digestive 0.868 0.8 – 0.942 0.000674 651 6504 all phecode
550.4 Umbilical hernia Digestive 1.14 1.1 – 1.18 2.63e-14 3705 37072 all phecode
550.5 Ventral hernia Digestive 1.15 1.11 – 1.19 8.34e-15 3435 34338 all phecode
555
Inflammatory bowel disease and other
Inflammatory bowel disease and other gastroenteritis and colitis
 Digestive 1.07 1.03 – 1.1 3.66e-05 4444 44442 all phecode
555.1 Regional enteritis Digestive 1.11 1.05 – 1.16 6.75e-05 1734 17340 all phecode
555.2 Ulcerative colitis Digestive 1.05 1.02 – 1.09 0.00402 3178 31786 all phecode
555.21 Ulcerative colitis (chronic) Digestive 0.988 0.904 – 1.08 0.791 538 5382 all phecode
556 Ulceration of the lower GI tract Digestive 1.14 1.07 – 1.22 4.09e-05 1055 10592 all phecode
556.1 Ulceration of intestine Digestive 1.16 1.07 – 1.26 0.000196 670 6714 all phecode
557 Intestinal malabsorption (non-celiac) Digestive 1.1 0.972 – 1.23 0.134 299 2987 all phecode
557.1 Celiac disease Digestive 1.17 1.11 – 1.22 3.95e-10 1837 18388 all phecode
558 Noninfectious gastroenteritis Digestive 1.14 1.12 – 1.16 5.78e-53 15492 155105 all phecode
559 Ileostomy status Digestive 1.12 1.06 – 1.18 1.27e-05 1656 16541 all phecode
560 Intestinal obstruction without mention of hernia Digestive 1.07 1.03 – 1.1 0.00012 3936 39337 all phecode
560.1 Paralytic ileus Digestive 1.1 1.01 – 1.2 0.0345 523 5231 all phecode
560.2 Impaction of intestine Digestive 1.03 0.914 – 1.17 0.591 268 2671 all phecode
560.3 Peritoneal or intestinal adhesions Digestive 1.08 1.01 – 1.16 0.0318 832 8317 all phecode
560.4 Other intestinal obstruction Digestive 1.06 1.02 – 1.1 0.00101 3358 33550 all phecode
561 Symptoms involving digestive system Digestive 1.08 1.06 – 1.1 6.84e-21 15772 157686 all phecode
561.1 Diarrhea Digestive 1.07 0.97 – 1.17 0.184 466 4653 all phecode
561.2 Flatulence Digestive 1.08 1.03 – 1.13 0.00276 1687 16859 all phecode
562 Diverticulosis and diverticulitis Digestive 1.11 1.1 – 1.12 2.55e-57 26714 211692 all phecode
562.1 Diverticulosis Digestive 1.11 1.09 – 1.12 5.91e-57 26672 211642 all phecode
563 Constipation Digestive 1.11 1.09 – 1.14 1.45e-25 10314 103140 all phecode
564 Functional digestive disorders Digestive 1.12 1.11 – 1.14 4.08e-61 21639 209949 all phecode
564.1 Irritable Bowel Syndrome Digestive 1.13 1.1 – 1.16 1.84e-17 5508 55117 all phecode
564.8
Abnormal findings on exam of gastrointestinal
Abnormal findings on exam of gastrointestinal tract/ abdominal area
 Digestive 1.13 1.08 – 1.19 1.44e-06 1645 16457 all phecode
564.9 Personal history of diseases of digestive system Digestive 1.13 1.11 – 1.15 3.1e-49 15186 151648 all phecode
565 Anal and rectal conditions Digestive 1.08 1.07 – 1.1 4.23e-21 14744 147535 all phecode
565.1 Anal and rectal polyp Digestive 1.09 1.07 – 1.12 5.51e-13 7351 73533 all phecode
567 Peritonitis and retroperitoneal infections Digestive 1.12 1.05 – 1.19 0.000888 929 9293 all phecode
568 Other disorders of peritoneum Digestive 1.14 1.1 – 1.18 2.48e-12 3262 32602 all phecode
568.1
Peritoneal adhesions (postoperative)
Peritoneal adhesions (postoperative) (postinfection)
 Digestive 1.14 1.1 – 1.18 1.58e-12 3101 30987 all phecode
569 Other disorders of intestine Digestive 1.11 1.07 – 1.14 1.95e-10 4192 41922 all phecode
569.1 Toxic gastroenteritis and colitis Digestive 1.25 1.06 – 1.47 0.0088 148 1479 all phecode
569.2 Gastrointestinal complications Digestive 0.992 0.905 – 1.09 0.856 486 4868 all phecode
571 Chronic liver disease and cirrhosis Digestive 1.39 1.34 – 1.45 6.77e-69 2957 29628 all phecode
571.5 Other chronic nonalcoholic liver disease Digestive 1.55 1.47 – 1.63 4.19e-66 1689 16917 all phecode
571.51 Cirrhosis of liver without mention of alcohol Digestive 1.31 1.09 – 1.58 0.00475 113 1139 all phecode
571.6 Primary biliary cirrhosis Digestive 1.12 0.983 – 1.27 0.0899 257 2568 all phecode
571.8
Liver abscess and sequelae of chronic liver
Liver abscess and sequelae of chronic liver disease
 Digestive 1.28 1.2 – 1.37 2.17e-14 976 9804 all phecode
571.81 Portal hypertension Digestive 1.42 1.3 – 1.55 2.61e-15 528 5285 all phecode
572 Ascites (non malignant) Digestive 1.19 1.13 – 1.25 6.22e-11 1544 15454 all phecode
573 Other disorders of liver Digestive 1.11 1.06 – 1.17 4.65e-05 1496 14982 all phecode
573.2 Liver replaced by transplant Digestive 1.37 1.12 – 1.68 0.00262 96 960 all phecode
573.3 Hepatomegaly Digestive 1.26 1.12 – 1.42 0.000163 297 2968 all phecode
573.5 Jaundice (not of newborn) Digestive 1.13 1.06 – 1.21 0.000423 896 8955 all phecode
573.7 Abnormal results of function study of liver Digestive 1.18 1.14 – 1.22 4.31e-21 3454 34597 all phecode
573.9 Abnormal serum enzyme levels Digestive 1.08 0.941 – 1.25 0.265 209 2089 all phecode
574 Cholelithiasis and cholecystitis Digestive 1.19 1.17 – 1.21 2.42e-93 15607 156123 all phecode
574.1 Cholelithiasis Digestive 1.18 1.16 – 1.21 1.63e-79 13549 135537 all phecode
574.11 Cholelithiasis with acute cholecystitis Digestive 1.24 1.18 – 1.31 6.28e-16 1506 15072 all phecode
574.12 Cholelithiasis with other cholecystitis Digestive 1.19 1.15 – 1.22 2.14e-33 5429 54289 all phecode
574.2 Calculus of bile duct Digestive 1.17 1.12 – 1.22 1.46e-14 2620 26191 all phecode
574.3 Cholecystitis without cholelithiasis Digestive 1.23 1.19 – 1.28 5.98e-26 2748 27523 all phecode
575 Other biliary tract disease Digestive 1.17 1.13 – 1.2 4.03e-20 3867 38724 all phecode
575.1 Cholangitis Digestive 1.19 1.09 – 1.3 0.000122 495 4945 all phecode
575.2 Obstruction of bile duct Digestive 1.15 1.07 – 1.24 0.000114 774 7756 all phecode
575.6 Cholesterolosis of gallbladder Digestive 1.32 1.2 – 1.45 1.49e-08 458 4577 all phecode
575.7 Other disorders of gallbladder Digestive 1.17 1.11 – 1.23 2.25e-08 1408 14107 all phecode
575.8 Other disorders of biliary tract Digestive 1.14 1.07 – 1.21 5.47e-05 1036 10367 all phecode
575.9
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of biliary tract
 Digestive 1.16 1.04 – 1.29 0.00942 348 3488 all phecode
577 Diseases of pancreas Digestive 1.21 1.17 – 1.26 2.76e-22 2668 26677 all phecode
577.1 Acute pancreatitis Digestive 1.23 1.17 – 1.28 1.29e-18 1996 19962 all phecode
577.2 Chronic pancreatitis Digestive 1.39 1.27 – 1.53 7.95e-13 515 5149 all phecode
577.3 Cyst and pseudocyst of pancreas Digestive 1.27 1.15 – 1.41 5.95e-06 365 3650 all phecode
578 Gastrointestinal hemorrhage Digestive 1.07 1.06 – 1.09 5.23e-22 20626 206278 all phecode
578.1 Hematemesis Digestive 1.15 1.1 – 1.21 1.39e-09 1958 19564 all phecode
578.2 Blood in stool Digestive 1.11 1.06 – 1.15 3.79e-07 2626 26283 all phecode
578.8 Hemorrhage of rectum and anus Digestive 1.06 1.04 – 1.08 2.41e-11 13073 130745 all phecode
578.9 Hemorrhage of gastrointestinal tract Digestive 1.06 1.03 – 1.09 3.24e-05 5275 52787 all phecode
579 Other symptoms involving abdomen and pelvis Digestive 1.09 1.03 – 1.15 0.00159 1548 15498 all phecode
579.2 Splenomegaly Digestive 1.17 1.06 – 1.29 0.0024 422 4246 all phecode
579.8 Nonspecific abnormal findings in stool contents Digestive 1.06 1.01 – 1.11 0.0282 1654 16540 all phecode
580 Nephritis; nephrosis; renal sclerosis Genitourinary 1.44 1.37 – 1.51 6.47e-44 1531 15350 all phecode
580.1 Glomerulonephritis Genitourinary 1.37 1.28 – 1.45 6.47e-23 1052 10544 all phecode
580.11 Proliferative glomerulonephritis Genitourinary 1.11 0.877 – 1.41 0.385 74 738 all phecode
580.12 Non-proliferative glomerulonephritis Genitourinary 1.3 1.09 – 1.55 0.00288 135 1360 all phecode
580.14 Chronic glomerulonephritis, NOS Genitourinary 1.39 1.3 – 1.48 3.1e-21 876 8769 all phecode
580.2
Nephrotic syndrome without mention of
Nephrotic syndrome without mention of glomerulonephritis
 Genitourinary 1.82 1.65 – 2 1.22e-35 468 4697 all phecode
580.3
Nephritis and nephropathy without mention of
Nephritis and nephropathy without mention of glomerulonephritis
 Genitourinary 1.34 1.18 – 1.53 9.14e-06 246 2460 all phecode
580.32
Nephritis and nephropathy with pathological
Nephritis and nephropathy with pathological lesion
 Genitourinary 1.32 1.16 – 1.5 2.21e-05 253 2529 all phecode
585 Renal failure Genitourinary 1.3 1.27 – 1.33 5.57e-102 6967 69751 all phecode
585.1 Acute renal failure Genitourinary 1.31 1.27 – 1.35 2.07e-69 4527 45305 all phecode
585.2 Renal failure NOS Genitourinary 1.22 1.16 – 1.29 1.04e-13 1460 14625 all phecode
585.3 Chronic renal failure [CKD] Genitourinary 1.43 1.37 – 1.49 1.53e-71 2644 26484 all phecode
585.31 Renal dialysis Genitourinary 1.34 1.23 – 1.47 1.71e-10 496 4955 all phecode
586 Other disorders of the kidney and ureters Genitourinary 1.12 1.08 – 1.16 9.35e-11 3355 33580 all phecode
586.1 Anatomical abnormatilies of kidney and ureters Genitourinary 1.13 0.983 – 1.3 0.0849 208 2089 all phecode
586.11 Small kidney Genitourinary 1.19 1.02 – 1.38 0.0253 179 1799 all phecode
586.2 Cyst of kidney, acquired Genitourinary 1.09 1.03 – 1.15 0.00424 1257 12582 all phecode
586.3 Vascular disorders of kidney/hypertrophy Genitourinary 1.1 0.874 – 1.38 0.422 80 799 all phecode
586.4 Stricture/obstruction of ureter Genitourinary 1.16 1.08 – 1.24 2.19e-05 910 9122 all phecode
587 Kidney replaced by transpant Genitourinary 1.18 1.06 – 1.32 0.00176 368 3683 all phecode
588 Disorders resulting from impaired renal function Genitourinary 1.28 1.05 – 1.57 0.0156 99 990 all phecode
589 Abnormal results of function study of kidney Genitourinary 1.09 0.908 – 1.32 0.344 116 1158 all phecode
590 Pyelonephritis Genitourinary 1.2 1.14 – 1.27 1.24e-10 1328 13285 all phecode
591 Urinary tract infection Genitourinary 1.13 1.11 – 1.15 2.59e-37 12400 123937 all phecode
592 Cystitis and urethritis Genitourinary 1.11 1.07 – 1.16 1.6e-08 2966 29661 all phecode
592.1 Cystitis Genitourinary 1.11 1.07 – 1.15 4.92e-08 2904 29035 all phecode
592.11 Acute cystitis Genitourinary 0.868 0.73 – 1.03 0.107 138 1372 all phecode
592.12 Chronic cystitis Genitourinary 1.13 1.06 – 1.21 0.000391 889 8890 all phecode
592.13 Chronic interstitial cystitis Genitourinary 1.02 0.896 – 1.16 0.758 249 2486 all phecode
592.2 Urethritis and urethral syndrome Genitourinary 1.13 0.962 – 1.32 0.138 165 1662 all phecode
593 Hematuria Genitourinary 1.08 1.07 – 1.1 4.73e-22 16068 160204 all phecode
594 Urinary calculus Genitourinary 1.17 1.14 – 1.2 5.5e-35 6376 63761 all phecode
594.1 Calculus of kidney Genitourinary 1.17 1.13 – 1.21 9.32e-18 3175 31757 all phecode
594.2 Calculus of lower urinary tract Genitourinary 1.18 1.1 – 1.27 1.11e-05 776 7764 all phecode
594.3 Calculus of ureter Genitourinary 1.19 1.14 – 1.24 5.96e-16 2401 24024 all phecode
594.8 Renal colic Genitourinary 1.18 1.13 – 1.24 3.67e-13 2050 20500 all phecode
595 Hydronephrosis Genitourinary 1.18 1.12 – 1.23 4.21e-12 1936 19395 all phecode
596 Other disorders of bladder Genitourinary 1.07 1.05 – 1.1 2.33e-11 9771 97778 all phecode
596.1 Bladder neck obstruction Genitourinary 1.05 1.01 – 1.1 0.0217 1969 19690 all phecode
596.5 Functional disorders of bladder Genitourinary 1.06 1.01 – 1.11 0.0286 1658 16572 all phecode
597 Other disorders of urethra and urinary tract Genitourinary 1.11 1.08 – 1.15 1.36e-10 3913 39135 all phecode
597.1 Urethral stricture (not specified as infectious) Genitourinary 1.12 1.08 – 1.16 1.52e-10 3317 33137 all phecode
597.2 Urinary complications NEC Genitourinary 1.29 1.03 – 1.61 0.0273 78 778 all phecode
598 Abnormal findings on examination of urine Genitourinary 1.05 1.02 – 1.09 0.00456 3528 35302 all phecode
598.9
Other nonspecific findings on examination of
Other nonspecific findings on examination of urine
 Genitourinary 1.07 0.954 – 1.2 0.245 304 3035 all phecode
599 Other symptoms/disorders or the urinary system Genitourinary 1.11 1.09 – 1.12 9.5e-41 18428 184311 all phecode
599.1 Urinary obstruction Genitourinary 1.02 0.873 – 1.19 0.807 166 1670 all phecode
599.2 Retention of urine Genitourinary 1.11 1.08 – 1.14 5.35e-16 6718 67168 all phecode
599.3 Dysuria Genitourinary 1.08 1.02 – 1.15 0.00891 1196 11967 all phecode
599.4 Urinary incontinence Genitourinary 1.13 1.11 – 1.16 6.77e-29 8748 87477 all phecode
599.5 Frequency of urination and polyuria Genitourinary 1.07 1.04 – 1.1 3.32e-05 4018 40144 all phecode
599.6 Oliguria and anuria Genitourinary 1.25 1.03 – 1.52 0.0264 105 1059 all phecode
599.8 Other symptoms involving urinary system Genitourinary 1.2 0.927 – 1.56 0.167 62 620 all phecode
599.9 Other abnormality of urination Genitourinary 1.08 1.03 – 1.13 0.000841 1913 19151 all phecode
600 Hyperplasia of prostate Genitourinary 1.05 1.03 – 1.07 1.58e-07 11093 87892 all phecode
601 Inflammatory diseases of prostate Genitourinary 1.08 1.04 – 1.13 0.00039 2081 20818 all phecode
601.1 Prostatitis Genitourinary 1.05 0.995 – 1.1 0.0789 1563 15644 all phecode
601.11 Acute prostatitis Genitourinary 1.04 0.913 – 1.19 0.543 234 2358 all phecode
601.12 Chronic prostatitis Genitourinary 0.996 0.932 – 1.06 0.898 910 9089 all phecode
601.3 Orchitis and epididymitis Genitourinary 0.853 0.659 – 1.1 0.224 59 588 all phecode
601.4 Balanoposthitis Genitourinary 1.19 1.06 – 1.34 0.00275 287 2864 all phecode
601.8
Other inflammatory disorders of male genital
Other inflammatory disorders of male genital organs
 Genitourinary 1.2 1.07 – 1.35 0.00213 303 3019 all phecode
602 Other disorders of prostate Genitourinary 1.06 1 – 1.12 0.0419 1341 13408 all phecode
603 Other disorders of testis Genitourinary 1.14 1.09 – 1.19 3.37e-09 2150 21512 all phecode
603.1 Hydrocele Genitourinary 1.15 1.09 – 1.21 1.18e-06 1339 13402 all phecode
604 Disorders of penis Genitourinary 1.18 1.14 – 1.22 3.17e-20 3280 32779 all phecode
604.1 Redundant prepuce and phimosis/BXO Genitourinary 1.18 1.14 – 1.23 4.11e-17 2719 27172 all phecode
605 Erectile dysfunction [ED] Genitourinary 1.24 1.1 – 1.4 0.000371 278 2800 all phecode
608 Other disorders of male genital organs Genitourinary 1.02 0.984 – 1.06 0.249 2822 28236 all phecode
609 Male infertility and abnormal spermatozoa Genitourinary 0.983 0.854 – 1.13 0.813 214 2138 all phecode
609.1 Infertility, male Genitourinary 0.89 0.691 – 1.15 0.367 63 638 all phecode
609.2 Abnormal spermatozoa Genitourinary 1.02 0.874 – 1.19 0.803 169 1698 all phecode
610 Benign mammary dysplasias Genitourinary 1 0.959 – 1.04 0.984 2482 24809 all phecode
610.1 Cystic mastopathy Genitourinary 0.909 0.849 – 0.974 0.00678 925 9250 all phecode
610.2 Fibroadenosis of breast Genitourinary 1.03 0.918 – 1.16 0.603 306 3057 all phecode
610.3 Fibrosclerosis of breast Genitourinary 1.06 0.936 – 1.19 0.369 302 3018 all phecode
610.4 Benign neoplasm of breast Genitourinary 0.997 0.943 – 1.05 0.91 1388 13865 all phecode
610.8 Other specified benign mammary dysplasias Genitourinary 1.09 1 – 1.18 0.0394 696 6954 all phecode
611 Abnormal findings on mammogram or breast exam Genitourinary 1.01 0.958 – 1.06 0.707 1574 15731 all phecode
611.1 Abnormal mammogram Genitourinary 1.04 0.798 – 1.35 0.773 57 569 all phecode
611.3 Lump or mass in breast Genitourinary 1.01 0.962 – 1.07 0.592 1522 15213 all phecode
612
Breast conditions, congenital or relating to
Breast conditions, congenital or relating to hormones
 Genitourinary 1.1 1.02 – 1.17 0.00837 887 8871 all phecode
612.2 Hypertrophy of breast (Gynecomastia) Genitourinary 1.08 1.01 – 1.16 0.0238 849 8490 all phecode
612.3 Congenital anomalies of breast Genitourinary 1.08 0.853 – 1.36 0.534 72 719 all phecode
613 Other nonmalignant breast conditions Genitourinary 1.07 1.02 – 1.13 0.00626 1651 16519 all phecode
613.1 Inflammatory disease of breast Genitourinary 1.11 1.02 – 1.19 0.0103 720 7210 all phecode
613.5 Mastodynia Genitourinary 1.14 0.898 – 1.44 0.29 77 768 all phecode
613.7 Other signs and symptoms in breast Genitourinary 0.968 0.895 – 1.05 0.415 702 7013 all phecode
613.8 Other specified disorders of breast Genitourinary 1.06 0.942 – 1.19 0.342 327 3278 all phecode
613.9 Breast disorder NOS Genitourinary 1.04 0.899 – 1.19 0.629 207 2069 all phecode
614 Inflammatory diseases of female pelvic organs Genitourinary 1.09 1.06 – 1.12 3.8e-10 5711 57118 all phecode
614.1
Pelvic peritoneal adhesions, female
Pelvic peritoneal adhesions, female (postoperative) (postinfection)
 Genitourinary 1.13 1.08 – 1.17 1.78e-08 2538 25363 all phecode
614.3 Pelvic inflammatory disease (PID) Genitourinary 1.15 1.07 – 1.23 0.000169 830 8308 all phecode
614.31 Acute inflammatory pelvic disease Genitourinary 1.41 1.08 – 1.85 0.0114 61 608 all phecode
614.32 Chronic inflammatory pelvic disease Genitourinary 1.19 1.08 – 1.32 0.000669 422 4221 all phecode
614.33 Pelvic inflammatory disease, NOS Genitourinary 1.07 0.957 – 1.19 0.243 351 3510 all phecode
614.4 Inflammatory diseases of uterus, except cervix Genitourinary 1.08 0.955 – 1.22 0.219 277 2775 all phecode
614.5
Inflammatory disease of cervix, vagina, and
Inflammatory disease of cervix, vagina, and vulva
 Genitourinary 1.06 1.02 – 1.1 0.00491 2601 26023 all phecode
614.51 Cervicitis and endocervicitis Genitourinary 1.02 0.963 – 1.08 0.506 1318 13189 all phecode
614.52 Vaginitis and vulvovaginitis Genitourinary 1.13 1.02 – 1.25 0.0147 428 4273 all phecode
614.53 Cyst or abscess of Bartholin's gland Genitourinary 1 0.928 – 1.08 0.971 755 7574 all phecode
614.54 Abscess or ulceration of vulva Genitourinary 1.27 1.12 – 1.44 0.000169 274 2737 all phecode
615 Endometriosis Genitourinary 1.1 1.07 – 1.14 2.56e-09 4029 40284 all phecode
617
Disorders secondary to childbirth, surgery
Disorders secondary to childbirth, surgery, trauma
 Genitourinary 1.1 0.971 – 1.24 0.138 304 3037 all phecode
618 Genital prolapse Genitourinary 1.08 1.05 – 1.1 9.96e-14 11689 116878 all phecode
618.1 Prolapse of vaginal walls Genitourinary 1.09 1.07 – 1.12 2.53e-13 7392 73940 all phecode
618.2 Uterine/Uterovaginal prolapse Genitourinary 1.05 1.02 – 1.08 0.000561 5393 53918 all phecode
618.5 Prolapse of vaginal vault after hysterectomy Genitourinary 1.13 1.03 – 1.23 0.0106 512 5125 all phecode
618.6 Vaginal enterocele, congenital or acquired Genitourinary 1.12 1.03 – 1.21 0.00603 680 6794 all phecode
619 Noninflammatory female genital disorders Genitourinary 1.06 1.03 – 1.08 2.15e-06 8726 87297 all phecode
619.1
Noninflammatory disorders of ovary, fallopian
Noninflammatory disorders of ovary, fallopian tube, and broad ligament
 Genitourinary 1.06 0.985 – 1.15 0.116 729 7284 all phecode
619.2 Disorders of uterus, NEC Genitourinary 1.06 1.02 – 1.1 0.00107 3324 33273 all phecode
619.3 Noninflammatory disorders of cervix Genitourinary 1.06 1.02 – 1.1 0.00515 2860 28608 all phecode
619.4 Noninflammatory disorders of vagina Genitourinary 0.99 0.942 – 1.04 0.683 1768 17669 all phecode
619.5 Noninflammatory disorders of vulva and perineum Genitourinary 1.02 0.961 – 1.08 0.557 1350 13489 all phecode
620 Dysplasia of female genital organs Genitourinary 1.04 0.826 – 1.32 0.718 72 720 all phecode
621 Endometrial hyperplasia Genitourinary 1.12 1.05 – 1.19 0.000427 1129 11294 all phecode
622 Polyp of female genital organs Genitourinary 1.04 1.02 – 1.06 9.88e-05 10480 104803 all phecode
622.1 Polyp of corpus uteri Genitourinary 1.05 1.02 – 1.07 0.00016 7857 78601 all phecode
622.2 Mucous polyp of cervix Genitourinary 1.01 0.973 – 1.04 0.667 3442 34387 all phecode
623 Hypertrophy of female genital organs Genitourinary 1.1 1.04 – 1.16 0.00164 1268 12684 all phecode
624 Symptoms involving female genital tract Genitourinary 1.07 0.991 – 1.15 0.0834 797 7961 all phecode
624.1 Dystrophy of female genital tract Genitourinary 1.11 0.97 – 1.27 0.128 237 2365 all phecode
624.2 Atrophy of female genital tract Genitourinary 1.1 0.999 – 1.22 0.0524 440 4398 all phecode
624.9 stress incontinence, female Genitourinary 1.15 1.12 – 1.18 9.28e-24 5865 58634 all phecode
625
Pain and other symptoms associated with female
Pain and other symptoms associated with female genital organs
 Genitourinary 1.04 1 – 1.08 0.051 2876 28740 all phecode
625.1 Dyspareunia Genitourinary 1.02 0.964 – 1.09 0.435 1188 11891 all phecode
626
Disorders of menstruation and other abnormal
Disorders of menstruation and other abnormal bleeding from female genital tract
 Genitourinary 1.09 1.07 – 1.11 3.27e-23 16168 115018 all phecode
626.1 Irregular menstrual cycle/bleeding Genitourinary 1.1 1.08 – 1.11 1.7e-23 14110 109918 all phecode
626.11 Absent or infrequent menstruation Genitourinary 0.968 0.792 – 1.18 0.75 109 1099 all phecode
626.12 Excessive or frequent menstruation Genitourinary 1.12 1.1 – 1.14 1.92e-25 9727 91749 all phecode
626.13 Irregular menstrual cycle Genitourinary 1.05 0.998 – 1.09 0.0634 1985 19829 all phecode
626.14 Irregular menstrual bleeding Genitourinary 1.08 1.05 – 1.12 5.7e-06 3804 38021 all phecode
626.2 Dysmenorrhea Genitourinary 1.13 1.07 – 1.18 1.85e-06 1778 17767 all phecode
626.4 Premenstrual tension syndromes Genitourinary 1.09 0.919 – 1.29 0.331 159 1587 all phecode
626.8 Infertility, female Genitourinary 0.966 0.912 – 1.02 0.233 1362 13613 all phecode
627 Menopausal and postmenopausal disorders Genitourinary 1.06 1.04 – 1.09 3.05e-09 10392 103948 all phecode
627.1 Postmenopausal bleeding Genitourinary 1.06 1.04 – 1.09 4.23e-08 9042 90439 all phecode
627.2 Symptomatic menopause Genitourinary 1.14 0.977 – 1.33 0.0978 183 1826 all phecode
627.3 Postmenopausal atrophic vaginitis Genitourinary 1.04 0.979 – 1.11 0.204 1111 11115 all phecode
627.4 Premenopausal menorrhagia Genitourinary 1.06 0.946 – 1.2 0.3 310 3097 all phecode
628 Ovarian cyst Genitourinary 1.11 1.07 – 1.14 7e-11 4747 47482 all phecode
634 Miscarriage; stillbirth Pregnancy Complications 0.951 0.923 – 0.98 0.00097 5218 36422 all phecode
634.1 Missed abortion/Hydatidiform mole Pregnancy Complications 0.918 0.862 – 0.977 0.0068 1136 11300 all phecode
634.3 Ectopic pregnancy Pregnancy Complications 1.08 0.966 – 1.22 0.169 331 3305 all phecode
635
Hemorrhage during pregnancy; childbirth and
Hemorrhage during pregnancy; childbirth and postpartum
 Pregnancy Complications 0.942 0.899 – 0.988 0.0139 1974 17372 all phecode
635.2
Antepartum hemorrhage, abruptio placentae, and
Antepartum hemorrhage, abruptio placentae, and placenta previa
 Pregnancy Complications 0.91 0.847 – 0.978 0.0101 866 8614 all phecode
635.3 Placenta previa and abruptio placenta Pregnancy Complications 0.942 0.888 – 1 0.0492 1270 12306 all phecode
636
Early or threatened labor; hemorrhage in early
Early or threatened labor; hemorrhage in early pregnancy
 Pregnancy Complications 0.996 0.953 – 1.04 0.848 2347 19972 all phecode
636.2 Early onset of delivery Pregnancy Complications 1.04 0.956 – 1.13 0.366 617 6144 all phecode
636.3 Hemorrhage in early pregnancy Pregnancy Complications 0.976 0.915 – 1.04 0.451 1082 10766 all phecode
638 Other high-risk pregnancy Pregnancy Complications 0.868 0.678 – 1.11 0.261 70 700 all phecode
642
Hypertension complicating pregnancy
Hypertension complicating pregnancy, childbirth, and the puerperium
 Pregnancy Complications 1.06 1 – 1.13 0.0493 1110 11074 all phecode
642.1 Preeclampsia and eclampsia Pregnancy Complications 1.06 0.944 – 1.2 0.313 307 3058 all phecode
643 Excessive vomiting in pregnancy Pregnancy Complications 0.984 0.854 – 1.13 0.829 215 2149 all phecode
643.1 Hyperemesis gravidarum Pregnancy Complications 0.942 0.796 – 1.11 0.485 153 1525 all phecode
645 Late pregnancy and failed induction Pregnancy Complications 0.93 0.876 – 0.988 0.0177 1250 12450 all phecode
646 Other complications of pregnancy NEC Pregnancy Complications 0.986 0.943 – 1.03 0.534 2228 20847 all phecode
647
Infectious and parasitic complications
Infectious and parasitic complications affecting pregnancy
 Pregnancy Complications 1.1 0.865 – 1.4 0.432 68 679 all phecode
647.1
Infections of genitourinary tract during
Infections of genitourinary tract during pregnancy
 Pregnancy Complications 0.99 0.873 – 1.12 0.88 275 2748 all phecode
649
Other conditions or status of the mother
Other conditions or status of the mother complicating pregnancy, childbirth, or the puerperium
 Pregnancy Complications 0.879 0.723 – 1.07 0.2 113 1129 all phecode
649.1
Diabetes or abnormal glucose tolerance
Diabetes or abnormal glucose tolerance complicating pregnancy
 Pregnancy Complications 1.62 1.39 – 1.89 5.2e-10 193 1922 all phecode
650 Normal delivery Pregnancy Complications 0.908 0.866 – 0.953 7.56e-05 1922 18973 all phecode
651 Multiple gestation Pregnancy Complications 0.989 0.882 – 1.11 0.85 346 3454 all phecode
652
Malposition and malpresentation of fetus or
Malposition and malpresentation of fetus or obstruction
 Pregnancy Complications 0.986 0.938 – 1.04 0.597 1716 16521 all phecode
653
Problems associated with amniotic cavity and
Problems associated with amniotic cavity and membranes
 Pregnancy Complications 0.95 0.898 – 1.01 0.0745 1401 13649 all phecode
654
Other and unspecified complications of birth
Other and unspecified complications of birth; puerperium affecting management of mother
 Pregnancy Complications 0.952 0.749 – 1.21 0.685 74 739 all phecode
655
Known or suspected fetal abnormality affecting
Known or suspected fetal abnormality affecting management of mother
 Pregnancy Complications 0.95 0.919 – 0.982 0.0022 4306 29454 all phecode
656 Other perinatal conditions of fetus or newborn Pregnancy Complications 1.02 0.838 – 1.24 0.838 109 1080 all phecode
661 Fetal distress and abnormal forces of labor Pregnancy Complications 0.932 0.891 – 0.974 0.00196 2265 18397 all phecode
663
Umbilical cord complications during labor and
Umbilical cord complications during labor and delivery
 Pregnancy Complications 0.969 0.886 – 1.06 0.491 532 5316 all phecode
665 Obstetrical/birth trauma Pregnancy Complications 0.917 0.889 – 0.945 2.44e-08 5313 29472 all phecode
669 Complications of labor and delivery NEC Pregnancy Complications 0.936 0.897 – 0.976 0.00215 2552 21174 all phecode
671
Venous/cerebrovascular complications embolism
Venous/cerebrovascular complications embolism in pregnancy and the puerperium
 Pregnancy Complications 0.984 0.839 – 1.16 0.846 164 1628 all phecode
674 Other complications of the puerperium NEC Pregnancy Complications 1.1 0.969 – 1.26 0.136 262 2605 all phecode
676
Other disorders of the breast associated with
Other disorders of the breast associated with childbirth and disorders of lactation
 Pregnancy Complications 0.988 0.762 – 1.28 0.924 63 624 all phecode
679 Complications of in utero procedures Dermatologic 0.787 0.599 – 1.04 0.0872 53 530 all phecode
681 Superficial cellulitis and abscess Dermatologic 1.2 1.17 – 1.23 6.85e-51 7200 72225 all phecode
681.1 Cellulitis and abscess of fingers/toes Dermatologic 1.15 1.05 – 1.25 0.0019 563 5647 all phecode
681.2 Cellulitis and abscess of face/neck Dermatologic 1.14 1.04 – 1.25 0.00382 520 5208 all phecode
681.3 Cellulitis and abscess of arm/hand Dermatologic 1.22 1.18 – 1.25 2.52e-44 5481 55014 all phecode
681.5 Cellulitis and abscess of leg, except foot Dermatologic 1.22 1.19 – 1.25 5.43e-46 5487 55074 all phecode
681.6 Cellulitis and abscess of foot, toe Dermatologic 1.22 1.18 – 1.25 1.24e-44 5444 54643 all phecode
681.7 Cellulitis and abscess of trunk Dermatologic 1.21 1.11 – 1.31 8.01e-06 597 5987 all phecode
686
Other local infections of skin and subcutaneous
Other local infections of skin and subcutaneous tissue
 Dermatologic 1.26 1.19 – 1.33 5.63e-16 1337 13427 all phecode
686.1 Carbuncle and furuncle Dermatologic 1.24 1.19 – 1.3 2.41e-23 2284 22925 all phecode
686.3 Pilonidal cyst Dermatologic 1.14 1.05 – 1.25 0.00175 583 5837 all phecode
686.4 Pyogenic granuloma Dermatologic 1.11 0.993 – 1.23 0.0674 362 3615 all phecode
687 Symptoms affecting skin Dermatologic 1.11 1.02 – 1.21 0.0203 548 5508 all phecode
687.1 Rash and other nonspecific skin eruption Dermatologic 1.1 1.05 – 1.14 5.15e-05 2146 21470 all phecode
687.2 Localized superficial swelling, mass, or lump Dermatologic 1.11 0.985 – 1.26 0.0849 283 2839 all phecode
687.3 Changes in skin texture Dermatologic 0.878 0.718 – 1.07 0.207 106 1070 all phecode
687.4 Disturbance of skin sensation Dermatologic 1.16 1.11 – 1.2 1.47e-13 2884 28859 all phecode
689 Disorder of skin and subcutaneous tissue NOS Dermatologic 1.04 1.02 – 1.07 0.00169 5747 57521 all phecode
690 Erythematosquamous dermatosis Dermatologic 0.919 0.72 – 1.17 0.497 71 710 all phecode
690.1 Seborrheic dermatitis Dermatologic 0.97 0.735 – 1.28 0.832 53 530 all phecode
691 Congenital anomalies of skin Dermatologic 1.01 0.844 – 1.22 0.877 120 1199 all phecode
694 Dyschromia and Vitiligo Dermatologic 1.02 0.956 – 1.09 0.545 986 9854 all phecode
694.1 Vitiligo Dermatologic 1.01 0.78 – 1.31 0.946 60 599 all phecode
694.2 Other dyschromia Dermatologic 0.999 0.929 – 1.08 0.986 782 7821 all phecode
694.3 Vascular disorders of skin Dermatologic 1.14 0.944 – 1.37 0.176 117 1170 all phecode
695 Erythematous conditions Dermatologic 1.11 1.07 – 1.16 9.45e-07 2379 23813 all phecode
695.1 Toxic erythema Dermatologic 1.24 1.02 – 1.5 0.0294 109 1090 all phecode
695.2 Bullous dermatoses Dermatologic 1.08 0.911 – 1.29 0.366 137 1365 all phecode
695.21 Dermatitis herpetiformis Dermatologic 1.14 0.88 – 1.47 0.326 57 569 all phecode
695.22 Pemphigus and pemphigoid Dermatologic 0.945 0.747 – 1.2 0.638 73 727 all phecode
695.3 Rosacea Dermatologic 1.17 1.04 – 1.32 0.00718 309 3097 all phecode
695.4 Lupus (localized and systemic) Dermatologic 1.02 0.919 – 1.13 0.744 411 4114 all phecode
695.41 Cutaneous lupus erythematosus Dermatologic 0.986 0.823 – 1.18 0.878 130 1295 all phecode
695.42 Systemic lupus erythematosus Dermatologic 1.03 0.924 – 1.15 0.59 340 3407 all phecode
695.7 Prurigo and Lichen Dermatologic 1.09 1.02 – 1.18 0.0175 775 7760 all phecode
695.8 Other specified erythematous conditions Dermatologic 1.25 1.1 – 1.43 0.000815 236 2359 all phecode
695.81 Erythema nodosum Dermatologic 1.28 1.01 – 1.62 0.0386 76 760 all phecode
695.9 Unspecified erythematous condition Dermatologic 1.06 0.969 – 1.17 0.193 467 4672 all phecode
696 Psoriasis and related disorders Dermatologic 1.19 1.14 – 1.25 9.37e-16 2252 22509 all phecode
696.4 Psoriasis Dermatologic 1.2 1.15 – 1.25 4.99e-16 2198 21969 all phecode
696.41 Psoriasis vulgaris Dermatologic 1.21 1.16 – 1.28 2.18e-14 1680 16796 all phecode
696.42 Psoriatic arthropathy Dermatologic 1.17 1.09 – 1.27 4.82e-05 706 7052 all phecode
697 Sarcoidosis Dermatologic 1.17 1.07 – 1.27 0.000512 539 5373 all phecode
698 Pruritus and related conditions Dermatologic 1.18 1.09 – 1.27 1.31e-05 782 7814 all phecode
700 Corns and callosities Dermatologic 1.04 0.927 – 1.17 0.484 291 2904 all phecode
701
Other hypertrophic and atrophic conditions of
Other hypertrophic and atrophic conditions of skin
 Dermatologic 1.05 1.02 – 1.08 0.00139 4663 46650 all phecode
701.1 Keratoderma, acquired Dermatologic 1.03 0.834 – 1.27 0.789 87 870 all phecode
701.2 Scar conditions and fibrosis of skin Dermatologic 1.02 0.98 – 1.07 0.296 2348 23478 all phecode
701.3 Circumscribed scleroderma Dermatologic 1.37 1.06 – 1.79 0.0171 61 610 all phecode
701.4 Keloid scar Dermatologic 1.04 0.906 – 1.2 0.557 216 2159 all phecode
701.5 Abnormal granulation tissue Dermatologic 1.01 0.921 – 1.12 0.78 455 4568 all phecode
701.6 Acquired acanthosis nigricans Dermatologic 1.22 0.989 – 1.49 0.0638 102 1019 all phecode
702
Degenerative skin conditions and other
Degenerative skin conditions and other dermatoses
 Dermatologic 1.01 0.979 – 1.03 0.639 5459 54587 all phecode
702.1 Actinic keratosis Dermatologic 0.992 0.953 – 1.03 0.705 2585 25842 all phecode
702.2 Seborrheic keratosis Dermatologic 1.02 0.98 – 1.06 0.369 3078 30772 all phecode
703 Diseases of nail, NOS Dermatologic 1.09 0.976 – 1.21 0.126 354 3539 all phecode
703.1 Ingrowing nail Dermatologic 1.14 1.07 – 1.22 0.000124 966 9660 all phecode
704 Diseases of hair and hair follicles Dermatologic 1.08 1.05 – 1.11 2.73e-07 5267 52727 all phecode
704.1 Alopecia Dermatologic 1.21 1.01 – 1.45 0.0366 125 1269 all phecode
704.8
Other specified diseases of hair and hair
Other specified diseases of hair and hair follicles
 Dermatologic 1.18 0.929 – 1.49 0.176 76 759 all phecode
705 Disorders of sweat glands Dermatologic 1.28 1.11 – 1.46 0.000532 228 2287 all phecode
705.3 Hidradenitis Dermatologic 1.37 1.18 – 1.59 4.64e-05 186 1868 all phecode
705.8 Hyperhidrosis Dermatologic 1.14 1.05 – 1.24 0.00163 591 5919 all phecode
706 Diseases of sebaceous glands Dermatologic 1.07 1.05 – 1.09 3.13e-09 8317 83195 all phecode
706.1 Acne Dermatologic 1.01 0.809 – 1.26 0.939 78 779 all phecode
706.2 Sebaceous cyst Dermatologic 1.07 1.04 – 1.09 3.89e-09 8787 87882 all phecode
707 Chronic ulcer of skin Dermatologic 1.41 1.35 – 1.48 8.54e-50 1953 19654 all phecode
707.1 Decubitus ulcer Dermatologic 1.21 1.13 – 1.29 2.48e-08 909 9097 all phecode
709 Diffuse diseases of connective tissue Dermatologic 1.18 1.14 – 1.23 1.66e-21 3432 34317 all phecode
709.2 Sicca syndrome Dermatologic 1.09 0.995 – 1.19 0.0634 508 5073 all phecode
709.3 Systemic sclerosis Dermatologic 1.09 0.935 – 1.27 0.27 176 1753 all phecode
709.6
Other specified diffuse diseases of connective
Other specified diffuse diseases of connective tissue
 Dermatologic 1.2 0.943 – 1.54 0.137 65 649 all phecode
709.7 Unspecified diffuse connective tissue disease Dermatologic 1.21 1.17 – 1.26 4.26e-22 2714 27144 all phecode
710
Osteomyelitis, periostitis, and other
Osteomyelitis, periostitis, and other infections involving bone
 Musculoskeletal 1.56 1.44 – 1.7 3.42e-26 602 6034 all phecode
710.1 Osteomyelitis Musculoskeletal 1.61 1.48 – 1.76 1.51e-27 556 5574 all phecode
710.12 Chronic osteomyelitis Musculoskeletal 1.4 1.21 – 1.62 4.67e-06 194 1947 all phecode
710.19 Unspecified osteomyelitis Musculoskeletal 1.72 1.56 – 1.9 5.08e-26 398 3997 all phecode
711 Arthropathy associated with infections Musculoskeletal 1.13 1.02 – 1.24 0.0168 421 4225 all phecode
711.1 Pyogenic arthritis Musculoskeletal 1.19 1.06 – 1.33 0.00252 328 3296 all phecode
712 Infective connective tissue disorders Musculoskeletal 1.35 1.07 – 1.7 0.0119 81 810 all phecode
713
Arthropathy associated with other disorders
Arthropathy associated with other disorders classified elsewhere
 Musculoskeletal 1.61 1.37 – 1.9 1.03e-08 148 1499 all phecode
713.5
Arthropathy associated with neurological
Arthropathy associated with neurological disorders
 Musculoskeletal 3.55 2.62 – 4.8 2.46e-16 65 669 all phecode
714
Rheumatoid arthritis and other inflammatory
Rheumatoid arthritis and other inflammatory polyarthropathies
 Musculoskeletal 1.22 1.19 – 1.26 4.82e-41 4832 48320 all phecode
714.1 Rheumatoid arthritis Musculoskeletal 1.22 1.19 – 1.26 1.97e-37 4372 43714 all phecode
715 Other inflammatory spondylopathies Musculoskeletal 1.17 1.12 – 1.24 4.01e-10 1659 16588 all phecode
715.1 Sacroiliitis NEC Musculoskeletal 1.1 0.913 – 1.33 0.317 113 1129 all phecode
715.2 Ankylosing spondylitis Musculoskeletal 1.13 1.04 – 1.23 0.0035 618 6177 all phecode
716 Other arthropathies Musculoskeletal 1.16 1.15 – 1.18 1.23e-164 37478 265375 all phecode
716.1 Unspecified polyarthropathy or polyarthritis Musculoskeletal 1.22 1.18 – 1.27 1.33e-30 3505 35090 all phecode
716.2 Unspecified monoarthritis Musculoskeletal 1.16 1.14 – 1.18 1.41e-68 15522 155339 all phecode
716.9 Arthropathy NOS Musculoskeletal 1.16 1.15 – 1.18 1.33e-159 35944 262308 all phecode
717 Polymyalgia Rheumatica Musculoskeletal 1.13 1.07 – 1.2 4.04e-05 1145 11480 all phecode
720 Spinal stenosis Musculoskeletal 1.18 1.14 – 1.22 1.46e-21 3705 37091 all phecode
721 Spondylosis and allied disorders Musculoskeletal 1.18 1.15 – 1.2 4.16e-43 7832 78318 all phecode
721.1 Spondylosis without myelopathy Musculoskeletal 1.18 1.15 – 1.21 1.21e-29 5045 50451 all phecode
721.2 Spondylosis with myelopathy Musculoskeletal 1.33 1.15 – 1.54 0.000167 189 1899 all phecode
721.8 Other allied disorders of spine Musculoskeletal 1.2 1.07 – 1.33 0.00134 352 3519 all phecode
722 Intervertebral disc disorders Musculoskeletal 1.16 1.14 – 1.19 3.52e-42 8978 89848 all phecode
722.1 Displacement of intervertebral disc Musculoskeletal 1.17 1.07 – 1.28 0.000514 512 5116 all phecode
722.6 Degeneration of intervertebral disc Musculoskeletal 1.19 1.15 – 1.24 2.26e-19 2831 28328 all phecode
722.8 Postlaminectomy syndrome Musculoskeletal 1.29 1 – 1.66 0.0483 67 669 all phecode
722.9 Other and unspecified disc disorder Musculoskeletal 1.13 1.1 – 1.17 1.37e-15 4407 44127 all phecode
723 Other disorders of cervical region Musculoskeletal 1.22 1.12 – 1.34 1.36e-05 517 5173 all phecode
723.1 Torticollis Musculoskeletal 1.16 0.957 – 1.41 0.13 107 1068 all phecode
724 Other and unspecified disorders of back Musculoskeletal 1.12 1.07 – 1.17 6e-07 2052 20514 all phecode
724.1 Disorders of sacrum Musculoskeletal 1.21 1.1 – 1.34 0.000211 403 4024 all phecode
724.2 Disorders of coccyx Musculoskeletal 1.21 1.09 – 1.34 0.000326 406 4054 all phecode
724.8 Other symptoms referable to back Musculoskeletal 1.64 1.27 – 2.13 0.000159 63 630 all phecode
724.9 Other unspecified back disorders Musculoskeletal 1.08 1.03 – 1.14 0.00245 1614 16139 all phecode
726 Peripheral enthesopathies and allied syndromes Musculoskeletal 1.14 1.12 – 1.16 1.21e-53 14663 146691 all phecode
726.1 Enthesopathy Musculoskeletal 1.14 1.12 – 1.16 2.94e-34 9589 95900 all phecode
726.2 Synoviopathy Musculoskeletal 1.28 1.14 – 1.43 1.77e-05 334 3336 all phecode
726.3 Bursitis Musculoskeletal 1.18 1.1 – 1.26 5.5e-06 854 8573 all phecode
727 Other disorders of synovium, tendon, and bursa Musculoskeletal 1.11 1.08 – 1.13 3.03e-16 7331 73332 all phecode
727.1 Synovitis and tenosynovitis Musculoskeletal 1.13 1.09 – 1.18 2.03e-10 2737 27406 all phecode
727.2 Bursitis disorders Musculoskeletal 1.08 0.891 – 1.32 0.421 103 1029 all phecode
727.4 Ganglion and cyst of synovium, tendon, and bursa Musculoskeletal 1.07 1.04 – 1.12 0.000133 3109 31085 all phecode
727.5 Rupture of synovium Musculoskeletal 1.05 0.97 – 1.15 0.218 586 5854 all phecode
727.6 Rupture of tendon, nontraumatic Musculoskeletal 1.16 1.04 – 1.3 0.00795 353 3527 all phecode
727.7 Contracture of tendon (sheath) Musculoskeletal 1.14 0.957 – 1.35 0.145 143 1429 all phecode
728 Disorders of muscle, ligament, and fascia Musculoskeletal 1.09 1.05 – 1.13 6.83e-07 3677 36788 all phecode
728.2 Laxity of ligament or hypermobility syndrome Musculoskeletal 1.07 0.963 – 1.18 0.22 412 4115 all phecode
728.7 Fasciitis Musculoskeletal 1.09 1.05 – 1.13 2.67e-07 3803 38045 all phecode
728.71
Contracture of palmar fascia [Dupuytren's
Contracture of palmar fascia [Dupuytren's disease]
 Musculoskeletal 1.09 1.06 – 1.13 4.98e-07 3477 34788 all phecode
729 Other disorders of soft tissues Musculoskeletal 1.18 1.15 – 1.22 1.69e-36 6014 60309 all phecode
729.1 Rheumatism, unspecified and fibrositis Musculoskeletal 1.2 1.13 – 1.28 2.87e-08 1005 10063 all phecode
729.3 Panniculitis Musculoskeletal 1.03 0.848 – 1.26 0.742 101 1009 all phecode
731
Osteitis deformans and osteopathies associated
Osteitis deformans and osteopathies associated with other disorders classified elsewhere
 Musculoskeletal 1.26 1.11 – 1.42 0.000242 276 2758 all phecode
731.1 Osteitis deformans [Paget's disease of bone] Musculoskeletal 1.25 1.1 – 1.42 0.000487 261 2609 all phecode
732 Osteochondropathies Musculoskeletal 1.08 0.976 – 1.19 0.14 467 4679 all phecode
732.1 Juvenile osteochondrosis Musculoskeletal 1.1 0.953 – 1.27 0.192 207 2068 all phecode
732.7 Osteochondritis dissecans Musculoskeletal 0.91 0.696 – 1.19 0.489 57 570 all phecode
733 Other disorders of bone and cartilage Musculoskeletal 1.05 1 – 1.1 0.0482 1777 17814 all phecode
733.2 Cyst of bone Musculoskeletal 1.08 0.962 – 1.22 0.192 311 3115 all phecode
733.4 Aseptic necrosis of bone Musculoskeletal 1.08 0.992 – 1.18 0.0753 540 5393 all phecode
733.6 Costochondritis Musculoskeletal 1.22 1.02 – 1.47 0.0282 128 1276 all phecode
733.8 Malunion and nonunion of fracture Musculoskeletal 1.06 0.998 – 1.12 0.059 1231 12313 all phecode
733.9 Chondromalacia Musculoskeletal 1.15 0.955 – 1.38 0.14 121 1206 all phecode
735 Acquired foot deformities Musculoskeletal 1.03 1.01 – 1.05 0.00963 9603 96090 all phecode
735.1 Flat foot Musculoskeletal 1.03 0.885 – 1.19 0.719 189 1910 all phecode
735.2 Acquired toe deformities Musculoskeletal 1.04 1.01 – 1.07 0.00442 5070 50712 all phecode
735.21 Hammer toe (acquired) Musculoskeletal 1.04 0.992 – 1.09 0.104 1929 19324 all phecode
735.23 Hallux rigidus Musculoskeletal 1.07 1.01 – 1.12 0.0173 1555 15527 all phecode
735.3 Hallux valgus (Bunion) Musculoskeletal 1 0.979 – 1.03 0.758 6643 66463 all phecode
736 Other acquired deformities of limbs Musculoskeletal 1.11 1.06 – 1.17 2.76e-05 1627 16282 all phecode
736.2 Acquired deformities of finger Musculoskeletal 0.969 0.854 – 1.1 0.631 248 2476 all phecode
737 Curvature of spine Musculoskeletal 1.06 0.994 – 1.12 0.0775 1128 11300 all phecode
737.3 Kyphoscoliosis and scoliosis Musculoskeletal 1.04 0.978 – 1.11 0.205 1061 10632 all phecode
738 Other acquired musculoskeletal deformity Musculoskeletal 1.12 1.07 – 1.18 1.62e-06 1904 19058 all phecode
738.4 Acquired spondylolisthesis Musculoskeletal 1.15 1.09 – 1.21 3.37e-07 1513 15147 all phecode
739 Contracture of joint Musculoskeletal 1.06 0.97 – 1.17 0.185 488 4884 all phecode
740 Osteoarthrosis Musculoskeletal 1.12 1.11 – 1.14 6.47e-73 27707 231603 all phecode
740.1 Osteoarthritis; localized Musculoskeletal 1.1 1.08 – 1.12 1.8e-34 17412 169419 all phecode
740.11 Osteoarthrosis, localized, primary Musculoskeletal 1.12 1.09 – 1.14 3.83e-24 8974 89750 all phecode
740.12 Osteoarthrosis, localized, secondary Musculoskeletal 0.986 0.884 – 1.1 0.795 348 3474 all phecode
740.2 Osteoarthrosis, generalized Musculoskeletal 1.16 1.07 – 1.26 0.000324 598 5969 all phecode
740.9 Osteoarthrosis NOS Musculoskeletal 1.16 1.14 – 1.18 6.29e-58 12270 122792 all phecode
741 Symptoms and disorders of the joints Musculoskeletal 1.14 1.1 – 1.18 1.88e-13 3563 35648 all phecode
741.1 Ankylosis of joint Musculoskeletal 1.23 1.01 – 1.5 0.0363 102 1019 all phecode
741.2 Stiffness of joint Musculoskeletal 1.13 1.04 – 1.23 0.00271 614 6146 all phecode
741.3 Difficulty in walking Musculoskeletal 1.2 1.01 – 1.41 0.0341 154 1540 all phecode
741.4 Joint effusions Musculoskeletal 1.19 1.13 – 1.25 2.27e-10 1418 14197 all phecode
741.5 Hemarthrosis Musculoskeletal 1.17 0.96 – 1.42 0.121 110 1100 all phecode
741.6 Villonodular synovitis Musculoskeletal 0.999 0.762 – 1.31 0.994 54 535 all phecode
742 Derangement of joint, non-traumatic Musculoskeletal 1.11 1.07 – 1.15 2.06e-07 2843 28441 all phecode
742.1 Loose body in joint Musculoskeletal 1.09 0.975 – 1.21 0.133 333 3337 all phecode
742.2
Pathological, developmental or recurrent
Pathological, developmental or recurrent dislocation
 Musculoskeletal 1.19 0.966 – 1.46 0.102 95 960 all phecode
742.8 Articular cartilage disorder Musculoskeletal 1.19 1.09 – 1.3 0.000119 500 4996 all phecode
742.9 Other derangement of joint Musculoskeletal 1.09 1.04 – 1.15 0.000142 1993 19926 all phecode
743
Osteoporosis, osteopenia and pathological
Osteoporosis, osteopenia and pathological fracture
 Musculoskeletal 1.03 1 – 1.05 0.0204 7563 75729 all phecode
743.1 Osteoporosis Musculoskeletal 1.02 0.996 – 1.05 0.0972 6400 64107 all phecode
743.11 Osteoporosis NOS Musculoskeletal 1.02 0.995 – 1.05 0.114 5549 55604 all phecode
743.13 Other specified osteoporosis Musculoskeletal 1.12 1.02 – 1.22 0.0145 529 5283 all phecode
743.2 Pathologic fracture Musculoskeletal 1.09 0.999 – 1.19 0.0524 516 5179 all phecode
743.9
Osteopenia or other disorder of bone and
Osteopenia or other disorder of bone and cartilage
 Musculoskeletal 1.02 0.949 – 1.1 0.583 815 8144 all phecode
745 Pain in joint Musculoskeletal 1.14 1.12 – 1.17 6.97e-30 7975 79789 all phecode
747 Cardiac and circulatory congenital anomalies Congenital Anomalies 1.16 1.11 – 1.2 6.8e-14 2802 28058 all phecode
747.1 Cardiac congenital anomalies Congenital Anomalies 1.17 1.12 – 1.21 4.01e-14 2628 26323 all phecode
747.11 Cardiac shunt/ heart septal defect Congenital Anomalies 0.974 0.893 – 1.06 0.553 584 5838 all phecode
747.12 Valvular heart disease/ heart chambers Congenital Anomalies 0.994 0.869 – 1.14 0.935 235 2358 all phecode
747.13 Congenital anomalies of great vessels Congenital Anomalies 1.25 1.19 – 1.31 2.25e-20 1816 18200 all phecode
747.2
Congenital anomalies of peripheral vascular
Congenital anomalies of peripheral vascular system
 Congenital Anomalies 1.11 0.944 – 1.3 0.21 167 1680 all phecode
748 Anomalies of respiratory system, congenital Congenital Anomalies 1.09 0.827 – 1.42 0.553 51 510 all phecode
749 Congenital anomalies of face and neck Congenital Anomalies 0.943 0.84 – 1.06 0.324 303 3029 all phecode
750 Digestive congenital anomalies Congenital Anomalies 0.963 0.89 – 1.04 0.349 686 6870 all phecode
750.1 Upper gastrointestinal congenital anomalies Congenital Anomalies 0.918 0.82 – 1.03 0.136 327 3263 all phecode
750.13 Congenital anomalies of mouth/tongue Congenital Anomalies 0.854 0.735 – 0.992 0.0384 191 1909 all phecode
750.2 Lower gastrointestinal congenital anomalies Congenital Anomalies 1.02 0.912 – 1.13 0.77 356 3574 all phecode
750.21 Congenital anomalies of intestine Congenital Anomalies 0.968 0.845 – 1.11 0.641 225 2256 all phecode
750.22
Congenital anomaly of gallbladder, bile ducts
Congenital anomaly of gallbladder, bile ducts, liver, pancreas
 Congenital Anomalies 1.1 0.907 – 1.34 0.329 117 1179 all phecode
751 Genitourinary congenital anomalies Congenital Anomalies 1 0.953 – 1.06 0.876 1527 15286 all phecode
751.1 Congenital anomalies of genital organs Congenital Anomalies 0.977 0.904 – 1.06 0.568 694 6932 all phecode
751.11 Congenital anomalies of female genital organs Congenital Anomalies 0.99 0.898 – 1.09 0.848 455 4546 all phecode
751.12 Congenital anomalies of male genital organs Congenital Anomalies 0.939 0.821 – 1.07 0.363 222 2217 all phecode
751.2 Congenital anomalies of urinary system Congenital Anomalies 1.04 0.97 – 1.12 0.266 836 8385 all phecode
751.21 Cystic kidney disease Congenital Anomalies 1.01 0.913 – 1.11 0.89 424 4246 all phecode
751.22 Other specified congenital anomalies of kidney Congenital Anomalies 1.08 0.972 – 1.21 0.147 333 3346 all phecode
752 Nervous system congenital anomalies Congenital Anomalies 1.17 1.04 – 1.31 0.00713 328 3307 all phecode
752.1 Neural tube defects Congenital Anomalies 1.09 0.958 – 1.24 0.187 253 2557 all phecode
752.11 Spina bifida Congenital Anomalies 1.06 0.922 – 1.23 0.402 208 2108 all phecode
752.2
Other specified congenital anomalies of nervous
Other specified congenital anomalies of nervous system
 Congenital Anomalies 1.4 1.1 – 1.77 0.00568 78 780 all phecode
753 Congenital anomalies of the eye Congenital Anomalies 1.24 1.03 – 1.49 0.0256 127 1270 all phecode
753.1 Congenital cataract and lens anomalies Congenital Anomalies 1.26 0.977 – 1.61 0.075 76 760 all phecode
754 Congenital musculoskeletal deformities of spine Congenital Anomalies 1.12 0.919 – 1.36 0.266 109 1099 all phecode
755 Congenital anomalies of limbs Congenital Anomalies 1.1 0.994 – 1.21 0.0651 425 4276 all phecode
755.1 Congenital deformities of feet Congenital Anomalies 1.1 0.959 – 1.27 0.169 208 2086 all phecode
755.6
Other congenital anomalies of lower limb
Other congenital anomalies of lower limb, including pelvic girdle
 Congenital Anomalies 1.06 0.905 – 1.25 0.463 160 1620 all phecode
755.61 Congenital hip dysplasia and deformity Congenital Anomalies 1.04 0.85 – 1.27 0.718 106 1070 all phecode
756 Other congenital musculoskeletal anomalies Congenital Anomalies 1.05 0.968 – 1.15 0.228 587 5872 all phecode
756.3
Congenital anomalies of muscle, tendon, fascia
Congenital anomalies of muscle, tendon, fascia, and connective tissue
 Congenital Anomalies 1.02 0.816 – 1.27 0.873 81 810 all phecode
756.5 Congenital osteodystrophies Congenital Anomalies 1.08 0.978 – 1.19 0.13 435 4356 all phecode
758 Chromosomal anomalies and genetic disorders Congenital Anomalies 0.909 0.771 – 1.07 0.26 148 1708 all phecode
758.1 Chromosomal anomalies Congenital Anomalies 0.943 0.737 – 1.21 0.641 60 830 all phecode
759 Other and unspecified congenital anomalies Congenital Anomalies 1.04 0.901 – 1.19 0.626 216 2159 all phecode
759.1 Anomalies of endocrine glands, congenital Congenital Anomalies 0.929 0.757 – 1.14 0.483 96 959 all phecode
760 Back pain Symptoms 1.16 1.13 – 1.18 3.61e-48 11126 111353 all phecode
761 Cervicalgia Symptoms 1.14 1.09 – 1.2 3.91e-08 1791 17901 all phecode
764 Sciatica Symptoms 1.16 1.11 – 1.21 2.04e-12 2372 23732 all phecode
766 Neuralgia, neuritis, and radiculitis NOS Symptoms 1.09 1.03 – 1.16 0.00389 1172 11738 all phecode
770 Myalgia and myositis unspecified Symptoms 1.17 1.08 – 1.27 0.000104 631 6311 all phecode
771 Musculoskeletal symptoms referable to limbs Symptoms 1.16 1.08 – 1.24 2.68e-05 870 8687 all phecode
771.1 Swelling of limb Symptoms 1.18 1.14 – 1.21 1.91e-26 4617 46330 all phecode
772 Symptoms of the muscles Symptoms 1.14 1.05 – 1.23 0.00146 659 6581 all phecode
773 Pain in limb Symptoms 1.15 1.12 – 1.18 2.13e-27 6209 62203 all phecode
780 Hypothermia/Chills Symptoms 1.18 1.01 – 1.37 0.0412 171 1719 all phecode
781
Symptoms involving nervous and musculoskeletal
Symptoms involving nervous and musculoskeletal systems
 Symptoms 1.16 1.11 – 1.22 3.59e-10 1870 18715 all phecode
782.3 Edema Symptoms 1.22 1.16 – 1.28 3.19e-15 1642 16450 all phecode
782.6 Pallor and flushing Symptoms 1.18 1.01 – 1.37 0.0358 175 1748 all phecode
783 Fever of unknown origin Symptoms 1.1 1.06 – 1.13 3.85e-08 3911 39105 all phecode
785 Abdominal pain Symptoms 1.08 1.07 – 1.1 1.59e-52 40080 301686 all phecode
788 Syncope and collapse Symptoms 1.11 1.09 – 1.14 6.29e-23 9069 90813 all phecode
789 Nausea and vomiting Symptoms 1.14 1.12 – 1.16 1.75e-41 11577 115807 all phecode
790 Nonspecific findings on examination of blood Symptoms 1.04 0.885 – 1.23 0.623 150 1500 all phecode
790.1 Elevated sedimentation rate Symptoms 1.28 1.04 – 1.58 0.0206 84 840 all phecode
790.6 Other abnormal blood chemistry Symptoms 1.07 1.04 – 1.1 1.38e-07 6357 63635 all phecode
791 Gangrene Symptoms 1.59 1.46 – 1.73 1.09e-26 549 5501 all phecode
792
Abnormal Papanicolaou smear of cervix and
Abnormal Papanicolaou smear of cervix and cervical HPV
 Symptoms 0.884 0.718 – 1.09 0.248 98 966 all phecode
793
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of musculoskeletal system
 Symptoms 1.02 0.863 – 1.21 0.804 134 1340 all phecode
793.2
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of other intrathoracic organs (echocardiogram, etc)
 Symptoms 1.07 0.98 – 1.16 0.138 565 5647 all phecode
794
Abnormal results of other function studies
Abnormal results of other function studies (bladder, pancreas, placenta, spleen, etc)
 Symptoms 0.868 0.718 – 1.05 0.142 120 1198 all phecode
797 Shock Symptoms 1.08 0.913 – 1.27 0.38 156 1559 all phecode
797.1 Cardiogenic shock Symptoms 1.26 1.03 – 1.54 0.0234 102 1020 all phecode
798 Malaise and fatigue Symptoms 1.13 1.09 – 1.17 2.96e-12 3408 34103 all phecode
798.1 Chronic fatigue syndrome Symptoms 1.1 1.01 – 1.19 0.0349 591 5913 all phecode
800 Fracture of lower limb Injuries & Poisonings 1.08 1.05 – 1.1 5.62e-09 7035 70329 all phecode
800.1 Fracture of neck of femur Injuries & Poisonings 1 0.953 – 1.05 1 1815 18152 all phecode
800.2 Fracture of unspecified part of femur Injuries & Poisonings 1.11 0.953 – 1.3 0.176 170 1693 all phecode
800.3 Fracture of tibia and fibula Injuries & Poisonings 1.08 1.04 – 1.13 0.000246 2158 21577 all phecode
800.4 Fracture of patella Injuries & Poisonings 1.09 1.01 – 1.17 0.0252 766 7661 all phecode
801 Fracture of ankle and foot Injuries & Poisonings 1.09 1.05 – 1.14 7.43e-05 2205 22041 all phecode
801.1 Fracture of foot Injuries & Poisonings 1.07 1.02 – 1.12 0.00528 1835 18346 all phecode
802 Fracture of pelvis Injuries & Poisonings 0.982 0.91 – 1.06 0.637 718 7185 all phecode
803 Fracture of upper limb Injuries & Poisonings 0.978 0.956 – 1 0.0532 8288 82880 all phecode
803.1 Fracture of humerus Injuries & Poisonings 1.05 0.999 – 1.1 0.0535 1691 16883 all phecode
803.2 Fracture of radius and ulna Injuries & Poisonings 0.947 0.92 – 0.974 0.000181 5215 52171 all phecode
803.3 Fracture of clavicle or scapula Injuries & Poisonings 1.01 0.957 – 1.06 0.764 1518 15186 all phecode
804 Fracture of hand or wrist Injuries & Poisonings 0.994 0.959 – 1.03 0.726 3339 33384 all phecode
805
Fracture of vertebral column without mention of
Fracture of vertebral column without mention of spinal cord injury
 Injuries & Poisonings 1.06 1.01 – 1.12 0.0284 1358 13565 all phecode
807 Fracture of ribs Injuries & Poisonings 1.02 0.952 – 1.1 0.52 776 7752 all phecode
809 Fracture of unspecified bones Injuries & Poisonings 1.03 0.971 – 1.09 0.345 1300 12998 all phecode
817 Concussion Injuries & Poisonings 0.955 0.836 – 1.09 0.499 243 2428 all phecode
818 Intracranial hemorrhage (injury) Injuries & Poisonings 1.08 0.993 – 1.18 0.071 522 5213 all phecode
819
Skull and face fracture and other intercranial
Skull and face fracture and other intercranial injury
 Injuries & Poisonings 1.02 0.98 – 1.06 0.348 2957 29596 all phecode
823 Torus fracture Injuries & Poisonings 1.06 1.01 – 1.11 0.0226 1673 16710 all phecode
830 Dislocation Injuries & Poisonings 1.04 0.991 – 1.08 0.113 2088 20872 all phecode
835 Internal derangement of knee Injuries & Poisonings 1.08 1.07 – 1.1 3.36e-21 15221 152247 all phecode
836 Traumatic arthropathy Injuries & Poisonings 1.19 1.09 – 1.3 0.00014 526 5267 all phecode
840 Sprains and strains Injuries & Poisonings 1.03 0.938 – 1.13 0.528 470 4697 all phecode
850 Hemorrhage or hematoma complicating a procedure Injuries & Poisonings 1.13 1.09 – 1.16 2.67e-16 5259 52626 all phecode
851
Complications of transplants and reattached
Complications of transplants and reattached limbs
 Injuries & Poisonings 1.15 0.974 – 1.36 0.0997 157 1567 all phecode
853 Complication of colostomy or enterostomy Injuries & Poisonings 1.22 1.11 – 1.33 1.5e-05 501 5010 all phecode
854
Complications of cardiac/vascular device
Complications of cardiac/vascular device, implant, and graft
 Injuries & Poisonings 1.26 1.2 – 1.32 4.77e-22 1826 18238 all phecode
857
Mechanical complication of unspecified
Mechanical complication of unspecified genitourinary device, implant, and graft
 Injuries & Poisonings 1.1 1.03 – 1.16 0.00178 1241 12418 all phecode
858 Complication of internal orthopedic device Injuries & Poisonings 1.12 1.08 – 1.17 2.57e-10 3158 31607 all phecode
859
Complication due to other implant and internal
Complication due to other implant and internal device
 Injuries & Poisonings 1.12 1.08 – 1.16 1.27e-09 3259 32599 all phecode
860 Bone marrow or stem cell transplant Neoplasms 0.947 0.733 – 1.22 0.677 68 680 all phecode
870 Open wounds of head; neck; and trunk Injuries & Poisonings 1.05 1.01 – 1.08 0.00935 3502 35062 all phecode
870.1 Open wound or laceration of eye or eyelid Injuries & Poisonings 1.08 0.952 – 1.22 0.241 272 2713 all phecode
870.2 Open wound of ear Injuries & Poisonings 0.996 0.861 – 1.15 0.957 196 1949 all phecode
870.3 Other open wound of head and face Injuries & Poisonings 1.04 1 – 1.08 0.0441 2904 29085 all phecode
870.4 Open wound of nose and sinus Injuries & Poisonings 0.974 0.851 – 1.11 0.702 220 2199 all phecode
870.6 Open wound of neck Injuries & Poisonings 0.913 0.719 – 1.16 0.457 68 678 all phecode
871 Open wounds of extremities Injuries & Poisonings 1.05 1.01 – 1.08 0.00663 4063 40648 all phecode
871.1 Open wound of hand except finger(s) Injuries & Poisonings 1.41 1.08 – 1.85 0.0124 53 530 all phecode
871.2 Open wound of finger(s) Injuries & Poisonings 1.09 0.888 – 1.34 0.402 91 900 all phecode
871.3 Open wound of foot except toe(s) alone Injuries & Poisonings 1.13 0.97 – 1.31 0.118 178 1785 all phecode
872 Traumatic amputation Injuries & Poisonings 1.03 0.938 – 1.13 0.53 475 4742 all phecode
873 Broken tooth Injuries & Poisonings 1.05 0.916 – 1.2 0.503 229 2289 all phecode
874 Complication of amputation stump Injuries & Poisonings 1.53 1.31 – 1.79 1.23e-07 169 1710 all phecode
905
Late effects of musculoskeletal and connective
Late effects of musculoskeletal and connective tissue injuries
 Injuries & Poisonings 1.1 0.937 – 1.29 0.24 157 1567 all phecode
907 Injuries to the nervous system Injuries & Poisonings 1.1 1.04 – 1.17 0.000775 1314 13140 all phecode
915 Superficial injury without mention of infection Injuries & Poisonings 1.12 1.08 – 1.15 5.67e-12 4260 42663 all phecode
916 Contusion Injuries & Poisonings 1.1 1.05 – 1.16 0.000304 1450 14506 all phecode
930 Allergic reaction to food Injuries & Poisonings 1.07 0.917 – 1.25 0.388 179 1807 all phecode
938 Dermatitis due to solar radiation Injuries & Poisonings 1 0.905 – 1.11 0.949 389 3899 all phecode
938.2 Chronic dermatitis due to solar radiation Injuries & Poisonings 0.96 0.844 – 1.09 0.529 252 2530 all phecode
939
Atopic/contact dermatitis due to other or
Atopic/contact dermatitis due to other or unspecified
 Dermatologic 1.06 1.02 – 1.11 0.00605 2094 20961 all phecode
941 Adverse reaction to serum or vaccine Injuries & Poisonings 1.05 0.918 – 1.21 0.457 225 2249 all phecode
942 Infusion and transfusion reaction Injuries & Poisonings 1.22 0.995 – 1.49 0.0562 104 1038 all phecode
946 Anaphylactic shock NOS Injuries & Poisonings 1.2 1.1 – 1.31 3.06e-05 550 5509 all phecode
947 Urticaria Injuries & Poisonings 1.2 1.08 – 1.33 0.000788 371 3707 all phecode
949 Allergies, other Injuries & Poisonings 1.11 1 – 1.23 0.0418 397 3989 all phecode
952
Spinal cord injury without evidence of spinal
Spinal cord injury without evidence of spinal bone injury
 Injuries & Poisonings 1.06 0.961 – 1.17 0.242 423 4224 all phecode
957 Injury to other and unspecified nerves Injuries & Poisonings 1.34 1.18 – 1.52 4.88e-06 269 2698 all phecode
958
Certain early complications of trauma or
Certain early complications of trauma or procedure
 Injuries & Poisonings 1.13 1.03 – 1.24 0.0105 491 4926 all phecode
958.1 Postoperative shock Injuries & Poisonings 1.52 1.15 – 1.99 0.00281 55 555 all phecode
958.2 Traumatic and surgical subcutaneous emphysema Injuries & Poisonings 0.86 0.687 – 1.08 0.189 74 740 all phecode
960 Poisoning by antibiotics Injuries & Poisonings 1.13 1.11 – 1.15 1.78e-55 18100 181147 all phecode
960.2 Allergy/adverse effect of penicillin Injuries & Poisonings 1.13 1.11 – 1.15 2.49e-49 15846 158623 all phecode
961 Poisoning by other anti-infectives Injuries & Poisonings 1.13 1.02 – 1.25 0.0161 420 4195 all phecode
961.1 Poisoning/allergy of sulfonamides Injuries & Poisonings 1.1 1.03 – 1.18 0.00709 869 8703 all phecode
962 Poisoning by hormones and synthetic substitutes Injuries & Poisonings 1.32 1.19 – 1.47 2.24e-07 371 3707 all phecode
962.3
Hormones and synthetic substitutes causing
Hormones and synthetic substitutes causing adverse effects in therapeutic use
 Injuries & Poisonings 1.35 1.21 – 1.5 3.66e-08 364 3638 all phecode
963 Poisoning by primarily systemic agents Injuries & Poisonings 1.19 1.04 – 1.36 0.0111 223 2228 all phecode
964
Poisoning by agents primarily affecting blood
Poisoning by agents primarily affecting blood constituents
 Injuries & Poisonings 1.1 0.978 – 1.24 0.111 282 2830 all phecode
964.1 Anticoagulants causing adverse effects Injuries & Poisonings 1.09 0.966 – 1.23 0.161 276 2770 all phecode
965
Poisoning by analgesics, antipyretics, and
Poisoning by analgesics, antipyretics, and antirheumatics
 Injuries & Poisonings 1.17 1.14 – 1.2 1.3e-32 6082 60875 all phecode
965.1
Opiates and related narcotics causing adverse
Opiates and related narcotics causing adverse effects in therapeutic use
 Injuries & Poisonings 1.16 1.1 – 1.24 9.63e-07 1144 11447 all phecode
965.2
Antirheumatics causing adverse effects in
Antirheumatics causing adverse effects in therapeutic use
 Injuries & Poisonings 1.2 1.09 – 1.32 0.000129 476 4767 all phecode
965.3
Salicylates causing adverse effects in
Salicylates causing adverse effects in therapeutic use
 Injuries & Poisonings 1.27 1.15 – 1.4 4.01e-06 403 4045 all phecode
966
Poisoning by anticonvulsants and
Poisoning by anticonvulsants and anti-Parkinsonism drugs
 Injuries & Poisonings 1.18 1.08 – 1.29 0.00034 512 5123 all phecode
967
Adverse effects of sedatives or other central
Adverse effects of sedatives or other central nervous system depressants and anesthetics
 Injuries & Poisonings 1.17 1.08 – 1.28 0.000218 583 5843 all phecode
969 Poisoning by psychotropic agents Injuries & Poisonings 1.21 1.15 – 1.26 2.97e-15 1950 19519 all phecode
971
Poisoning by drugs primarily affecting the
Poisoning by drugs primarily affecting the autonomic nervous system
 Injuries & Poisonings 1.17 1.01 – 1.36 0.0323 190 1908 all phecode
972
Poisoning by agents primarily affecting the
Poisoning by agents primarily affecting the cardiovascular system
 Injuries & Poisonings 1.4 1.23 – 1.58 9.11e-08 271 2717 all phecode
972.6 Antihypertensive agents causing adverse effects Injuries & Poisonings 1.23 0.988 – 1.52 0.0647 84 849 all phecode
973
Poisoning by agents primarily affecting the
Poisoning by agents primarily affecting the gastrointestinal system
 Injuries & Poisonings 1.23 1.01 – 1.49 0.0402 108 1080 all phecode
974
Poisoning by water, mineral, and uric acid
Poisoning by water, mineral, and uric acid metabolism drugs
 Injuries & Poisonings 1.46 1.2 – 1.77 0.00013 101 1018 all phecode
975
Poisoning by agents primarily acting on the
Poisoning by agents primarily acting on the smooth and skeletal muscles and respiratory system
 Injuries & Poisonings 1.14 0.891 – 1.46 0.299 64 640 all phecode
976
Poisoning by agents primarily affecting skin &
Poisoning by agents primarily affecting skin & mucous membrane, ophthalmological, otorhinolaryngological, & dental drugs
 Injuries & Poisonings 1.36 1.04 – 1.77 0.0233 58 580 all phecode
977 Personal history of allergy to medicinal agents Injuries & Poisonings 1.14 0.997 – 1.31 0.0547 234 2337 all phecode
979 Adverse drug events and drug allergies Injuries & Poisonings 1.19 1.1 – 1.29 1.34e-05 698 6966 all phecode
981
Toxic effect of (non-ethyl) alcohol and
Toxic effect of (non-ethyl) alcohol and petroleum and other solvents
 Injuries & Poisonings 1.1 0.95 – 1.28 0.197 200 1999 all phecode
986 Toxic effect of carbon monoxide Injuries & Poisonings 1.11 0.853 – 1.44 0.44 62 620 all phecode
987 Toxic effect of other gases, fumes, or vapors Injuries & Poisonings 1.32 1.07 – 1.61 0.00787 105 1049 all phecode
988 Toxic effect of noxious substances eaten as food Injuries & Poisonings 1.01 0.831 – 1.22 0.952 111 1128 all phecode
989
Toxic effect of other substances, chiefly
Toxic effect of other substances, chiefly nonmedicinal as to source
 Injuries & Poisonings 0.839 0.677 – 1.04 0.108 89 890 all phecode
990 Effects radiation NOS Injuries & Poisonings 1.09 1.05 – 1.13 1.3e-05 3113 31140 all phecode
994 Sepsis and SIRS Injuries & Poisonings 1.13 1.09 – 1.18 2.64e-11 3028 30268 all phecode
994.2 Sepsis Injuries & Poisonings 1.13 1.09 – 1.18 2.64e-11 3028 30268 all phecode
008 Intestinal infection Infectious Diseases 1.07 1.05 – 1.1 6.19e-09 7801 83500 exclusion phecode
008.5 Bacterial enteritis Infectious Diseases 1.1 1.06 – 1.15 4.57e-06 2432 25627 exclusion phecode
008.52 Intestinal infection due to C. difficile Infectious Diseases 1.07 0.98 – 1.16 0.133 575 6126 exclusion phecode
008.6 Viral Enteritis Infectious Diseases 1.09 1.01 – 1.18 0.0209 743 8128 exclusion phecode
008.7 Intestinal infection due to protozoa Infectious Diseases 1.11 0.853 – 1.45 0.434 53 526 exclusion phecode
010 Tuberculosis Infectious Diseases 0.94 0.795 – 1.11 0.465 154 1538 exclusion phecode
038 Septicemia Infectious Diseases 1.05 1.02 – 1.09 0.00329 3616 39127 exclusion phecode
038.1 Gram negative septicemia Infectious Diseases 1.07 0.995 – 1.16 0.0686 733 7938 exclusion phecode
038.2 Gram positive septicemia Infectious Diseases 1.03 0.933 – 1.14 0.535 413 4672 exclusion phecode
041 Bacterial infection NOS Infectious Diseases 1.08 1.06 – 1.1 8.13e-15 10505 113294 exclusion phecode
041.1 Staphylococcus infections Infectious Diseases 1.09 1.05 – 1.14 9.5e-06 2641 29478 exclusion phecode
041.2 Streptococcus infection Infectious Diseases 1.05 0.996 – 1.11 0.0685 1436 15459 exclusion phecode
041.4 E. coli Infectious Diseases 1.08 1.03 – 1.12 0.000698 2350 25798 exclusion phecode
053 Herpes zoster Infectious Diseases 1.12 1.01 – 1.25 0.0348 370 3849 exclusion phecode
053.1 Herpes zoster with nervous system complications Infectious Diseases 1.14 0.909 – 1.43 0.255 87 886 exclusion phecode
054 Herpes simplex Infectious Diseases 1.04 0.895 – 1.2 0.625 200 1993 exclusion phecode
070 Viral hepatitis Infectious Diseases 1.03 0.945 – 1.13 0.473 527 5587 exclusion phecode
070.1 Viral hepatitis A Infectious Diseases 1.12 0.861 – 1.45 0.409 63 653 exclusion phecode
070.2 Viral hepatitis B Infectious Diseases 0.98 0.817 – 1.18 0.827 118 1254 exclusion phecode
070.3 Viral hepatitis C Infectious Diseases 0.994 0.871 – 1.14 0.935 234 2444 exclusion phecode
070.4 Chronic hepatitis Infectious Diseases 1.04 0.915 – 1.19 0.537 243 2621 exclusion phecode
070.9 Hepatitis NOS Infectious Diseases 1.26 1.12 – 1.41 7.99e-05 317 4032 exclusion phecode
071 Human immunodeficiency virus [HIV] disease Infectious Diseases 0.956 0.808 – 1.13 0.594 137 1384 exclusion phecode
071.1 HIV infection, symptomatic Infectious Diseases 0.923 0.765 – 1.11 0.399 107 1090 exclusion phecode
078 Viral warts & HPV Infectious Diseases 1.15 1.07 – 1.23 6.8e-05 927 9515 exclusion phecode
079 Viral infection Infectious Diseases 1.04 0.999 – 1.08 0.0544 2526 26371 exclusion phecode
079.1 Varicella infection Infectious Diseases 1.19 0.919 – 1.55 0.184 61 613 exclusion phecode
080 Postoperative infection Infectious Diseases 1.11 1.07 – 1.14 8.94e-10 3928 42268 exclusion phecode
081
Infection/inflammation of internal prosthetic
Infection/inflammation of internal prosthetic device; implant; and graft
 Infectious Diseases 1.09 1.05 – 1.14 7.36e-05 2215 23313 exclusion phecode
090
Sexually transmitted infections (not HIV or
Sexually transmitted infections (not HIV or hepatitis)
 Infectious Diseases 1.03 0.781 – 1.35 0.858 60 662 exclusion phecode
1000 Burns Injuries & Poisonings 1.03 0.943 – 1.13 0.502 527 5463 exclusion phecode
1001 Foreign body injury Injuries & Poisonings 1.03 0.967 – 1.09 0.368 1110 11318 exclusion phecode
1002
Symptoms concerning nutrition, metabolism, and
Symptoms concerning nutrition, metabolism, and development
 Injuries & Poisonings 1.03 0.999 – 1.06 0.0553 4996 51572 exclusion phecode
1004
Other signs and symptoms involving emotional
Other signs and symptoms involving emotional state
 Injuries & Poisonings 0.988 0.873 – 1.12 0.847 265 2835 exclusion phecode
1005 Other symptoms Injuries & Poisonings 1.07 1.01 – 1.13 0.0207 1294 13556 exclusion phecode
1006 Crushing injury Injuries & Poisonings 0.945 0.827 – 1.08 0.399 237 2403 exclusion phecode
1007 Injury to blood vessels Injuries & Poisonings 1.03 0.899 – 1.17 0.692 236 2392 exclusion phecode
1008 Crushing or internal injury to organs Injuries & Poisonings 1.02 0.958 – 1.09 0.492 944 9490 exclusion phecode
1009 Injury, NOS Injuries & Poisonings 1.06 1.03 – 1.08 5.36e-06 7818 80029 exclusion phecode
1010 Other tests Injuries & Poisonings 1.09 1.06 – 1.12 3.26e-09 5217 55996 exclusion phecode
1011 Complications of surgical and medical procedures Injuries & Poisonings 1.09 1.07 – 1.12 2.23e-14 8339 85978 exclusion phecode
1012 Late effect Injuries & Poisonings 1.09 0.883 – 1.35 0.412 95 998 exclusion phecode
1013 Asphyxia and hypoxemia Injuries & Poisonings 1.01 0.898 – 1.15 0.816 283 2995 exclusion phecode
1014 Effects of heat, cold and air pressure Injuries & Poisonings 1.05 0.815 – 1.35 0.707 62 622 exclusion phecode
1015 Effects of other external causes Injuries & Poisonings 1.07 1.04 – 1.11 3.44e-05 3770 40032 exclusion phecode
1019
Other ill-defined and unknown causes of
Other ill-defined and unknown causes of morbidity and mortality
 Injuries & Poisonings 1.07 1.05 – 1.09 7.69e-14 14592 150541 exclusion phecode
110 Dermatophytosis / Dermatomycosis Infectious Diseases 1.11 0.969 – 1.26 0.135 252 2617 exclusion phecode
110.1 Dermatophytosis Infectious Diseases 1.11 0.971 – 1.27 0.128 247 2562 exclusion phecode
110.11 Dermatophytosis of nail Infectious Diseases 1.04 0.813 – 1.32 0.77 72 708 exclusion phecode
110.12 Althete's foot Infectious Diseases 1.12 0.937 – 1.35 0.209 126 1320 exclusion phecode
112 Candidiasis Infectious Diseases 1.08 1.03 – 1.14 0.000859 1898 19991 exclusion phecode
117 Mycoses Infectious Diseases 1.04 0.917 – 1.19 0.509 248 2530 exclusion phecode
117.4 Aspergillosis Infectious Diseases 0.988 0.835 – 1.17 0.891 151 1525 exclusion phecode
130 Spirochetal infection Infectious Diseases 0.84 0.665 – 1.06 0.146 79 764 exclusion phecode
133 Arthropod-borne diseases Infectious Diseases 0.831 0.638 – 1.08 0.169 64 644 exclusion phecode
134 Helminthiases Infectious Diseases 1.11 0.923 – 1.34 0.259 119 1222 exclusion phecode
134.1 Intestinal helminthiases Infectious Diseases 1.05 0.857 – 1.29 0.635 99 1022 exclusion phecode
136 Other infectious and parasitic diseases Infectious Diseases 1.2 1.04 – 1.4 0.0151 189 1924 exclusion phecode
145 Cancer of mouth Neoplasms 1.05 0.965 – 1.14 0.253 608 5992 exclusion phecode
145.2 Cancer of tongue Neoplasms 0.996 0.884 – 1.12 0.954 292 2888 exclusion phecode
145.3 Cancer of major salivary glands Neoplasms 1.27 1.03 – 1.55 0.0233 104 996 exclusion phecode
145.5 Cancer of the mouth floor Neoplasms 0.825 0.61 – 1.12 0.213 49 502 exclusion phecode
149 Cancer of larynx, pharynx, nasal cavities Neoplasms 1.09 0.998 – 1.18 0.0565 572 5872 exclusion phecode
149.1 Cancer of oropharynx Neoplasms 1.15 1 – 1.32 0.0466 229 2341 exclusion phecode
149.4 Cancer of larynx Neoplasms 1.05 0.917 – 1.2 0.486 231 2424 exclusion phecode
149.9 Cancer of of nasal cavities Neoplasms 1.09 0.825 – 1.43 0.554 55 543 exclusion phecode
150 Cancer of esophagus Neoplasms 1 0.924 – 1.08 0.998 676 7038 exclusion phecode
151 Cancer of stomach Neoplasms 1.06 0.971 – 1.16 0.183 504 5252 exclusion phecode
153 Colorectal cancer Neoplasms 1.03 1 – 1.07 0.0344 4216 42788 exclusion phecode
153.2 Colon cancer Neoplasms 1.04 1 – 1.08 0.0317 2858 28989 exclusion phecode
153.3
Malignant neoplasm of rectum, rectosigmoid
Malignant neoplasm of rectum, rectosigmoid junction, and anus
 Neoplasms 1.01 0.962 – 1.06 0.745 1984 20217 exclusion phecode
155 Cancer of liver and intrahepatic bile duct Neoplasms 1.15 1.03 – 1.28 0.0159 327 3715 exclusion phecode
155.1 Malignant neoplasm of liver, primary Neoplasms 1.2 1 – 1.45 0.0495 114 1454 exclusion phecode
157 Pancreatic cancer Neoplasms 1.17 1.08 – 1.27 0.000254 576 6096 exclusion phecode
158
Neoplasm of unspecified nature of digestive
Neoplasm of unspecified nature of digestive system
 Neoplasms 0.994 0.93 – 1.06 0.863 967 9951 exclusion phecode
159
Malignant neoplasm of other and ill-defined
Malignant neoplasm of other and ill-defined sites within the digestive organs and peritoneum
 Neoplasms 1.04 1.01 – 1.07 0.0101 5079 51987 exclusion phecode
159.2
Malignant neoplasm of small intestine
Malignant neoplasm of small intestine, including duodenum
 Neoplasms 0.999 0.856 – 1.17 0.987 172 1773 exclusion phecode
159.3
Malignant neoplasm of gallbladder and
Malignant neoplasm of gallbladder and extrahepatic bile ducts
 Neoplasms 1.08 0.926 – 1.25 0.337 183 1911 exclusion phecode
159.4
Malignant neoplasm of retroperitoneum and
Malignant neoplasm of retroperitoneum and peritoneum
 Neoplasms 1.09 0.938 – 1.28 0.249 177 1800 exclusion phecode
164 Cancer of intrathoracic organs Neoplasms 1.01 0.763 – 1.33 0.949 56 562 exclusion phecode
165 Cancer within the respiratory system Neoplasms 1.1 1.05 – 1.14 9.82e-06 2559 26211 exclusion phecode
165.1 Cancer of bronchus; lung Neoplasms 1.08 1.04 – 1.14 0.000511 2019 20736 exclusion phecode
170 Cancer of bone and connective tissue Neoplasms 0.93 0.839 – 1.03 0.166 407 4098 exclusion phecode
170.1 Bone cancer Neoplasms 0.915 0.761 – 1.1 0.343 123 1237 exclusion phecode
170.2 Cancer of connective tissue Neoplasms 0.956 0.85 – 1.08 0.454 308 3112 exclusion phecode
172 Skin cancer Neoplasms 0.993 0.975 – 1.01 0.449 12674 126217 exclusion phecode
172.1 Melanomas of skin, dx or hx Neoplasms 0.972 0.933 – 1.01 0.181 2538 25249 exclusion phecode
172.11 Melanomas of skin Neoplasms 0.974 0.935 – 1.01 0.207 2568 25565 exclusion phecode
172.2 Other non-epithelial cancer of skin Neoplasms 0.996 0.976 – 1.02 0.711 10324 102723 exclusion phecode
172.3 Carcinoma in situ of skin Neoplasms 0.994 0.915 – 1.08 0.879 617 6227 exclusion phecode
173 Neoplasm of uncertain behavior of skin Neoplasms 1.05 0.895 – 1.22 0.569 169 1726 exclusion phecode
174 Breast cancer Neoplasms 1.01 0.987 – 1.02 0.56 12089 121554 exclusion phecode
174.1 Breast cancer [female] Neoplasms 1.01 0.989 – 1.03 0.399 11895 119587 exclusion phecode
174.11 Malignant neoplasm of female breast Neoplasms 1.01 0.987 – 1.03 0.52 11201 112851 exclusion phecode
174.3 Neoplasm of uncertain behavior of breast Neoplasms 1.05 0.861 – 1.29 0.619 109 1103 exclusion phecode
175 Acquired absence of breast Neoplasms 1 0.96 – 1.05 0.91 2267 23059 exclusion phecode
180 Cervical cancer and dysplasia Neoplasms 1.02 0.977 – 1.07 0.344 2101 21052 exclusion phecode
180.1 Cervical cancer Neoplasms 0.951 0.839 – 1.08 0.438 263 2628 exclusion phecode
180.3
Cervical intraepithelial neoplasia [CIN]
Cervical intraepithelial neoplasia [CIN] [Cervical dysplasia]
 Neoplasms 1.04 0.99 – 1.09 0.129 2006 20110 exclusion phecode
182 Malignant neoplasm of uterus Neoplasms 1.02 0.964 – 1.09 0.45 1172 12252 exclusion phecode
184 Cancer of other female genital organs Neoplasms 1.07 1.01 – 1.13 0.0218 1317 13206 exclusion phecode
184.1
Malignant neoplasm of ovary and other uterine
Malignant neoplasm of ovary and other uterine adnexa
 Neoplasms 1.05 0.986 – 1.13 0.123 926 9253 exclusion phecode
184.11 Malignant neoplasm of ovary Neoplasms 1.06 0.99 – 1.14 0.0917 899 8989 exclusion phecode
184.2
Cancer of other female genital organs
Cancer of other female genital organs (excluding uterus and ovary)
 Neoplasms 1.06 0.943 – 1.2 0.314 292 2931 exclusion phecode
185 Cancer of prostate Neoplasms 1.02 0.991 – 1.05 0.177 5561 53416 exclusion phecode
187 Cancer of other male genital organs Neoplasms 1.03 0.928 – 1.14 0.591 409 4176 exclusion phecode
187.1
Malignant neoplasm of unspecified male genital
Malignant neoplasm of unspecified male genital organ
 Neoplasms 1.01 0.774 – 1.31 0.95 61 652 exclusion phecode
187.2 Malignant neoplasm of testis Neoplasms 0.956 0.843 – 1.08 0.484 262 2693 exclusion phecode
187.8
Neoplasm of uncertain behavior of male genital
Neoplasm of uncertain behavior of male genital organs
 Neoplasms 1.13 0.907 – 1.4 0.283 101 1018 exclusion phecode
189
Cancer of urinary organs (incl. kidney and
Cancer of urinary organs (incl. kidney and bladder)
 Neoplasms 1.05 1.02 – 1.09 0.00429 3716 38439 exclusion phecode
189.1 Cancer of kidney and renal pelvis Neoplasms 1.07 1 – 1.14 0.0411 964 10024 exclusion phecode
189.11 Malignant neoplasm of kidney, except pelvis Neoplasms 1.09 1.02 – 1.17 0.00925 924 9659 exclusion phecode
189.12 Malignant neoplasm of renal pelvis Neoplasms 0.841 0.652 – 1.08 0.182 62 608 exclusion phecode
189.2 Cancer of bladder Neoplasms 1.05 1.01 – 1.1 0.0258 2133 22199 exclusion phecode
189.21 Malignant neoplasm of bladder Neoplasms 1.06 1.01 – 1.11 0.0251 1895 19748 exclusion phecode
189.4 Malignant neoplasm of other urinary organs Neoplasms 0.866 0.72 – 1.04 0.125 134 1315 exclusion phecode
190 Cancer of eye Neoplasms 0.979 0.834 – 1.15 0.793 161 1637 exclusion phecode
191
Manlignant and unknown neoplasms of brain and
Manlignant and unknown neoplasms of brain and nervous system
 Neoplasms 1.01 0.932 – 1.1 0.8 649 6455 exclusion phecode
191.1 Cancer of brain and nervous system Neoplasms 1.01 0.919 – 1.1 0.913 536 5303 exclusion phecode
191.11 Cancer of brain Neoplasms 1 0.911 – 1.1 0.999 498 4914 exclusion phecode
193 Thyroid cancer Neoplasms 1.04 0.928 – 1.16 0.51 320 3328 exclusion phecode
194 Cancer of other endocrine glands Neoplasms 0.946 0.753 – 1.19 0.634 81 896 exclusion phecode
195 Cancer, suspected or other Neoplasms 1.04 1.02 – 1.06 9.98e-07 15717 155208 exclusion phecode
195.1 Malignant neoplasm, other Neoplasms 1.04 1.02 – 1.06 2.02e-06 15068 149539 exclusion phecode
197 Chemotherapy Neoplasms 1.07 1.06 – 1.09 2.31e-20 19777 201681 exclusion phecode
198 Secondary malignant neoplasm Neoplasms 1.05 1.02 – 1.07 3.4e-05 8818 89754 exclusion phecode
198.1 Secondary malignancy of lymph nodes Neoplasms 1.02 0.991 – 1.05 0.184 4996 50682 exclusion phecode
198.2 Secondary malignancy of respiratory organs Neoplasms 1.04 0.991 – 1.08 0.116 2085 21259 exclusion phecode
198.3
Secondary malignant neoplasm of digestive
Secondary malignant neoplasm of digestive systems
 Neoplasms 1.03 0.976 – 1.09 0.285 1433 14603 exclusion phecode
198.4 Secondary malignant neoplasm of liver Neoplasms 1.04 0.998 – 1.08 0.0615 2439 24960 exclusion phecode
198.5 Secondary malignancy of brain/spine Neoplasms 1.01 0.942 – 1.09 0.716 798 7968 exclusion phecode
198.6 Secondary malignancy of bone Neoplasms 1.08 1.03 – 1.13 0.00118 1979 20192 exclusion phecode
198.7 Secondary malignant neoplasm of skin Neoplasms 1.05 0.897 – 1.23 0.534 174 1775 exclusion phecode
199 Neoplasm of uncertain behavior Neoplasms 1.08 1.02 – 1.15 0.00671 1319 13484 exclusion phecode
199.4 Neurofibromatosis Neoplasms 0.998 0.809 – 1.23 0.988 91 905 exclusion phecode
200 Myeloproliferative disease Neoplasms 1.12 1.05 – 1.2 0.000974 889 9257 exclusion phecode
200.1 Polycythemia vera Neoplasms 1.09 0.976 – 1.22 0.123 331 3575 exclusion phecode
201 Hodgkin's disease Neoplasms 0.979 0.859 – 1.12 0.752 240 2447 exclusion phecode
202 Cancer of other lymphoid, histiocytic tissue Neoplasms 1 0.956 – 1.05 0.998 2095 21255 exclusion phecode
202.2 Non-Hodgkins lymphoma Neoplasms 0.983 0.935 – 1.03 0.501 1669 16881 exclusion phecode
202.21 Nodular lymphoma Neoplasms 0.931 0.833 – 1.04 0.214 340 3414 exclusion phecode
202.24 Large cell lymphoma Neoplasms 1.05 0.958 – 1.14 0.309 538 5448 exclusion phecode
204 Leukemia Neoplasms 1.08 1.03 – 1.14 0.00318 1528 15471 exclusion phecode
204.1 Lymphoid leukemia Neoplasms 1.1 1 – 1.2 0.0443 521 5374 exclusion phecode
204.11 Lymphoid leukemia, acute Neoplasms 1.18 0.897 – 1.56 0.234 52 529 exclusion phecode
204.12 Lymphoid leukemia, chronic Neoplasms 1.09 0.99 – 1.2 0.0782 453 4700 exclusion phecode
204.2 Myeloid leukemia Neoplasms 1.11 1.01 – 1.23 0.0377 436 4302 exclusion phecode
204.21 Myeloid leukemia, acute Neoplasms 1.11 0.986 – 1.24 0.0844 311 3041 exclusion phecode
204.22 Myeloid leukemia, chronic Neoplasms 1.1 0.911 – 1.32 0.333 137 1359 exclusion phecode
204.4 Multiple myeloma Neoplasms 1.03 0.938 – 1.12 0.582 517 5179 exclusion phecode
208 Benign neoplasm of colon Neoplasms 1.06 1.04 – 1.07 1.38e-12 18008 180018 exclusion phecode
210 Benign neoplasm of lip, oral cavity, and pharynx Neoplasms 1.04 0.973 – 1.12 0.24 901 9212 exclusion phecode
211
Benign neoplasm of other parts of digestive
Benign neoplasm of other parts of digestive system
 Neoplasms 1.07 1.03 – 1.1 3.12e-05 4765 49410 exclusion phecode
212
Benign neoplasm of respiratory and
Benign neoplasm of respiratory and intrathoracic organs
 Neoplasms 1.11 0.99 – 1.25 0.0743 319 3256 exclusion phecode
213 Benign neoplasm of bone and articular cartilage Neoplasms 1.02 0.907 – 1.15 0.737 304 3023 exclusion phecode
214 Lipoma Neoplasms 1.06 1.03 – 1.09 1.08e-05 5824 58607 exclusion phecode
214.1 Lipoma of skin and subcutaneous tissue Neoplasms 1.06 1.03 – 1.09 0.000341 4307 43303 exclusion phecode
215
Other benign neoplasm of connective and other
Other benign neoplasm of connective and other soft tissue
 Neoplasms 1.05 0.985 – 1.12 0.139 1055 10460 exclusion phecode
216 Benign neoplasm of skin Neoplasms 1.01 0.989 – 1.04 0.304 7257 72741 exclusion phecode
217 Vascular hamartomas and non-neoplastic nevi Neoplasms 1.04 0.959 – 1.14 0.32 587 5954 exclusion phecode
217.1 Nevus, non-neoplastic Neoplasms 1.05 0.964 – 1.15 0.256 551 5598 exclusion phecode
218 Benign neoplasm of uterus Neoplasms 1.06 1.03 – 1.08 2.94e-07 9606 96769 exclusion phecode
218.1 Uterine leiomyoma Neoplasms 1.05 1.03 – 1.08 8.7e-07 9813 98814 exclusion phecode
218.2 Other benign neoplasm of uterus Neoplasms 1.03 0.921 – 1.15 0.602 336 3427 exclusion phecode
220 Benign neoplasm of ovary Neoplasms 1.02 0.967 – 1.08 0.443 1358 13942 exclusion phecode
221 Benign neoplasm of other female genital organs Neoplasms 0.979 0.845 – 1.13 0.774 200 2113 exclusion phecode
222 Benign neoplasm of male genital organs Neoplasms 1.1 0.924 – 1.3 0.292 148 1462 exclusion phecode
223
Benign neoplasm of kidney and other urinary
Benign neoplasm of kidney and other urinary organs
 Neoplasms 1.23 1.04 – 1.46 0.0144 156 1600 exclusion phecode
224 Benign neoplasm of eye Neoplasms 0.906 0.749 – 1.1 0.311 114 1213 exclusion phecode
224.1 Benign neoplasm of eye, uveal Neoplasms 0.904 0.695 – 1.18 0.454 56 632 exclusion phecode
225
Benign neoplasm of brain and other parts of
Benign neoplasm of brain and other parts of nervous system
 Neoplasms 1.05 0.978 – 1.13 0.173 765 7697 exclusion phecode
225.1
Benign neoplasm of brain, cranial nerves
Benign neoplasm of brain, cranial nerves, meninges
 Neoplasms 1.04 0.967 – 1.13 0.275 726 7322 exclusion phecode
225.2 Benign neoplasm of spinal cord, meninges Neoplasms 1.21 0.919 – 1.58 0.176 55 565 exclusion phecode
226 Benign neoplasm of thyroid glands Neoplasms 1.07 0.938 – 1.22 0.314 251 2537 exclusion phecode
227
Benign neoplasm of other endocrine glands and
Benign neoplasm of other endocrine glands and related structures
 Neoplasms 1.05 0.972 – 1.13 0.23 757 8145 exclusion phecode
227.1 Benign neoplasm of adrenal gland Neoplasms 1.1 0.935 – 1.3 0.249 153 1741 exclusion phecode
227.2 Benign neoplasm of parathyroid gland Neoplasms 1.03 0.921 – 1.16 0.591 338 3497 exclusion phecode
227.3
Benign neoplasm of pituitary gland and
Benign neoplasm of pituitary gland and craniopharyngeal duct (pouch)
 Neoplasms 1.06 0.94 – 1.2 0.331 272 2944 exclusion phecode
228 Hemangioma and lymphangioma, any site Neoplasms 1.03 0.974 – 1.08 0.324 1494 15077 exclusion phecode
229 Benign neoplasm of unspecified sites Neoplasms 1.02 0.979 – 1.07 0.315 2281 22844 exclusion phecode
240 Simple and unspecified goiter Endocrine/metabolic 1.16 1.06 – 1.26 0.00117 554 5744 exclusion phecode
241 Nontoxic nodular goiter Endocrine/metabolic 1.06 0.991 – 1.13 0.0933 1055 10605 exclusion phecode
241.1 Nontoxic uninodular goiter Endocrine/metabolic 1.1 0.997 – 1.21 0.0577 453 4518 exclusion phecode
241.2 Nontoxic multinodular goiter Endocrine/metabolic 1.01 0.932 – 1.1 0.783 641 6466 exclusion phecode
242 Thyrotoxicosis with or without goiter Endocrine/metabolic 1.13 1.08 – 1.19 1.35e-06 1673 17648 exclusion phecode
242.1 Graves' disease Endocrine/metabolic 1.16 1.05 – 1.28 0.00435 418 4347 exclusion phecode
242.2 Toxic multinodular goiter Endocrine/metabolic 1.02 0.819 – 1.26 0.875 86 869 exclusion phecode
242.3 Exophthalmos Endocrine/metabolic 1.1 0.911 – 1.32 0.333 126 1301 exclusion phecode
244 Hypothyroidism Endocrine/metabolic 1.11 1.09 – 1.13 1.93e-29 13227 138345 exclusion phecode
244.1 Secondary hypothyroidism Endocrine/metabolic 1.14 1.07 – 1.21 0.000105 1001 10545 exclusion phecode
244.2 Acquired hypothyroidism Endocrine/metabolic 1.06 0.852 – 1.31 0.614 87 957 exclusion phecode
244.4 Hypothyroidism NOS Endocrine/metabolic 1.11 1.09 – 1.13 2.8e-27 12609 132481 exclusion phecode
245 Thyroiditis Endocrine/metabolic 0.982 0.869 – 1.11 0.772 272 2761 exclusion phecode
245.2 Chronic thyroiditis Endocrine/metabolic 1.08 0.936 – 1.24 0.298 206 2085 exclusion phecode
245.21 Chronic lymphocytic thyroiditis Endocrine/metabolic 1.08 0.936 – 1.24 0.294 201 2015 exclusion phecode
246 Other disorders of thyroid Endocrine/metabolic 1.14 1.02 – 1.26 0.0176 371 3790 exclusion phecode
250 Diabetes mellitus Endocrine/metabolic 2.94 2.86 – 3.03 5.35e-1237 5756 181935 exclusion phecode
250.1 Type 1 diabetes Endocrine/metabolic 1.68 1.45 – 1.96 1.02e-11 172 27032 exclusion phecode
250.11 Type 1 diabetes with ketoacidosis Endocrine/metabolic 1.66 0.998 – 2.77 0.0511 12 2342 exclusion phecode
250.12 Type 1 diabetes with renal manifestations Endocrine/metabolic 2.02 0.795 – 5.11 0.139 1 750 exclusion phecode
250.13 Type 1 diabetes with ophthalmic manifestations Endocrine/metabolic 1.59 0.793 – 3.2 0.191 6 4637 exclusion phecode
250.14 Type 1 diabetes with neurological manifestations Endocrine/metabolic 0.77 0.368 – 1.61 0.489 3 1587 exclusion phecode
250.2 Type 2 diabetes Endocrine/metabolic 3.49 3.38 – 3.6 8.31e-1319 4878 166402 exclusion phecode
250.21 Type 2 diabetes with ketoacidosis Endocrine/metabolic 2.91 1.72 – 4.9 6.3e-05 12 1018 exclusion phecode
250.22 Type 2 diabetes with renal manifestations Endocrine/metabolic 2.18 1.31 – 3.63 0.00263 10 1969 exclusion phecode
250.23 Type 2 diabetes with ophthalmic manifestations Endocrine/metabolic 4.35 3.2 – 5.93 1.07e-20 46 9635 exclusion phecode
250.24 Type 2 diabetes with neurological manifestations Endocrine/metabolic 3.2 2.17 – 4.72 4.58e-09 21 4949 exclusion phecode
250.4 Abnormal glucose Endocrine/metabolic 1.51 1.37 – 1.67 2.87e-16 423 6683 exclusion phecode
250.41 Impaired fasting glucose Endocrine/metabolic 1.58 1.36 – 1.83 1.39e-09 186 2598 exclusion phecode
250.42 Other abnormal glucose Endocrine/metabolic 1.49 1.31 – 1.7 2.14e-09 240 4099 exclusion phecode
250.5 Glycosuria or Acetonuria Endocrine/metabolic 1.29 1.04 – 1.6 0.0225 93 1287 exclusion phecode
250.6 Polyneuropathy in diabetes Endocrine/metabolic 2.23 1.44 – 3.46 0.000346 14 3419 exclusion phecode
250.7 Diabetic retinopathy Endocrine/metabolic 1.9 1.53 – 2.37 7.79e-09 76 12416 exclusion phecode
251.1 Hypoglycemia Endocrine/metabolic 1.33 1.18 – 1.51 5.7e-06 272 9153 exclusion phecode
252 Disorders of parathyroid gland Endocrine/metabolic 1.08 0.998 – 1.16 0.0552 768 8265 exclusion phecode
252.1 Hyperparathyroidism Endocrine/metabolic 1.07 0.985 – 1.15 0.116 685 7393 exclusion phecode
252.2 Hypoparathyroidism Endocrine/metabolic 1.39 1.16 – 1.67 0.000443 124 1345 exclusion phecode
253
Disorders of the pituitary gland and its
Disorders of the pituitary gland and its hypothalamic control
 Endocrine/metabolic 1.13 1.04 – 1.23 0.00409 585 6425 exclusion phecode
253.1 Pituitary hyperfunction Endocrine/metabolic 1.14 0.973 – 1.34 0.104 162 1772 exclusion phecode
253.11 Acromegaly and gigantism Endocrine/metabolic 1.29 1.03 – 1.62 0.0269 82 901 exclusion phecode
253.2 Pituitary hypofunction Endocrine/metabolic 1.16 1.01 – 1.34 0.0392 216 2443 exclusion phecode
253.3 Diabetes insipidus Endocrine/metabolic 1.38 1.09 – 1.76 0.00852 70 868 exclusion phecode
253.7 Other disorders of neurohypophysis Endocrine/metabolic 1.02 0.849 – 1.21 0.868 137 1477 exclusion phecode
255 Disorders of adrenal glands Endocrine/metabolic 1.15 1.05 – 1.26 0.00194 539 6034 exclusion phecode
255.1 Adrenal hyperfunction Endocrine/metabolic 1.18 0.989 – 1.4 0.0658 142 1704 exclusion phecode
255.11 Cushing's syndrome Endocrine/metabolic 1.18 0.935 – 1.49 0.163 79 984 exclusion phecode
255.12 Hyperaldosteronism Endocrine/metabolic 1.23 0.955 – 1.59 0.108 62 724 exclusion phecode
255.2 Adrenal hypofunction Endocrine/metabolic 1.11 0.991 – 1.25 0.0707 310 3436 exclusion phecode
255.21 Glucocorticoid deficiency Endocrine/metabolic 1.12 0.993 – 1.25 0.0657 309 3426 exclusion phecode
256 Ovarian dysfunction Endocrine/metabolic 1.11 0.967 – 1.27 0.14 223 2355 exclusion phecode
256.4 Polycystic ovaries Endocrine/metabolic 1.09 0.946 – 1.27 0.225 192 2054 exclusion phecode
257 Testicular dysfunction Endocrine/metabolic 1.17 0.973 – 1.4 0.0956 134 1510 exclusion phecode
257.1 Testicular hypofunction Endocrine/metabolic 1.23 1.02 – 1.48 0.0326 125 1437 exclusion phecode
258 Iatrogenic endocrine disorders Endocrine/metabolic 1.14 0.909 – 1.43 0.259 80 958 exclusion phecode
259 Other endocrine disorders Endocrine/metabolic 1.16 0.966 – 1.39 0.113 133 1439 exclusion phecode
260 Protein-calorie malnutrition Endocrine/metabolic 1.08 0.936 – 1.25 0.286 185 1908 exclusion phecode
260.1 Cachexia Endocrine/metabolic 1.21 0.905 – 1.61 0.201 46 478 exclusion phecode
260.6 Anorexia Endocrine/metabolic 1.05 0.975 – 1.13 0.196 754 7811 exclusion phecode
261 Vitamin deficiency Endocrine/metabolic 1.09 1.02 – 1.16 0.0101 1030 11349 exclusion phecode
261.2 Vitamin B-complex deficiencies Endocrine/metabolic 1.09 1 – 1.18 0.0405 646 7125 exclusion phecode
261.4 Vitamin D deficiency Endocrine/metabolic 1.06 0.954 – 1.18 0.281 387 4256 exclusion phecode
261.41 Rickets or osteomalacia Endocrine/metabolic 1.1 0.864 – 1.4 0.442 71 738 exclusion phecode
262 Mineral deficiency NEC Endocrine/metabolic 1.13 0.985 – 1.3 0.08 216 2262 exclusion phecode
269 Proteinuria Endocrine/metabolic 1.22 1.08 – 1.38 0.00122 278 3150 exclusion phecode
270
Disorders of protein plasma/amino-acid
Disorders of protein plasma/amino-acid transport and metabolism
 Endocrine/metabolic 0.958 0.845 – 1.09 0.509 265 2832 exclusion phecode
270.3 Disorders of plasma protein metabolism Endocrine/metabolic 0.955 0.835 – 1.09 0.506 232 2426 exclusion phecode
270.32 Paraproteinemia Endocrine/metabolic 1.01 0.863 – 1.19 0.877 164 1769 exclusion phecode
270.33 Amyloidosis Endocrine/metabolic 1.1 0.905 – 1.34 0.331 104 1061 exclusion phecode
270.35 Macroglobulinemia Endocrine/metabolic 0.791 0.618 – 1.01 0.0627 67 646 exclusion phecode
271
Disorders of carbohydrate transport and
Disorders of carbohydrate transport and metabolism
 Endocrine/metabolic 1.39 1.15 – 1.68 0.000585 130 1523 exclusion phecode
271.3
Intestinal disaccharidase deficiencies and
Intestinal disaccharidase deficiencies and disaccharide malabsorption
 Endocrine/metabolic 1.33 1.09 – 1.62 0.0046 116 1326 exclusion phecode
272 Disorders of lipoid metabolism Endocrine/metabolic 1.16 1.14 – 1.17 5.31e-120 28950 224168 exclusion phecode
272.1 Hyperlipidemia Endocrine/metabolic 1.16 1.14 – 1.17 2.45e-120 28885 223940 exclusion phecode
272.11 Hypercholesterolemia Endocrine/metabolic 1.16 1.15 – 1.17 4.31e-114 26890 217030 exclusion phecode
272.12 Hyperglyceridemia Endocrine/metabolic 1.4 1.04 – 1.89 0.0259 47 554 exclusion phecode
272.13 Mixed hyperlipidemia Endocrine/metabolic 1.39 1.15 – 1.66 0.000456 120 1555 exclusion phecode
272.9 Unspecified disorder of lipoid metabolism Endocrine/metabolic 1.14 0.981 – 1.34 0.0866 161 1985 exclusion phecode
274 Gout and other crystal arthropathies Endocrine/metabolic 1.19 1.14 – 1.23 5.92e-20 3155 34506 exclusion phecode
274.1 Gout Endocrine/metabolic 1.19 1.14 – 1.24 2.62e-17 2649 29328 exclusion phecode
274.11 Gouty arthropathy Endocrine/metabolic 1.2 0.978 – 1.47 0.0814 94 1039 exclusion phecode
274.2 Crystal arthropathies Endocrine/metabolic 1.18 1.08 – 1.28 0.000273 556 5758 exclusion phecode
274.21 Chondrocalcinosis Endocrine/metabolic 1.21 1.1 – 1.32 5.43e-05 513 5241 exclusion phecode
275 Disorders of mineral metabolism Endocrine/metabolic 1.07 1.02 – 1.12 0.00547 1840 19677 exclusion phecode
275.1 Disorders of iron metabolism Hematopoietic 1.01 0.93 – 1.1 0.779 577 6082 exclusion phecode
275.3 Disorders of magnesium metabolism Endocrine/metabolic 1.12 0.999 – 1.26 0.0523 308 3509 exclusion phecode
275.5 Disorders of calcium/phosphorus metabolism Endocrine/metabolic 1.09 1.02 – 1.16 0.00652 1055 11243 exclusion phecode
275.53 Disorders of phosphorus metabolism Endocrine/metabolic 1.22 1.03 – 1.45 0.0236 151 1592 exclusion phecode
276
Disorders of fluid, electrolyte, and acid-base
Disorders of fluid, electrolyte, and acid-base balance
 Endocrine/metabolic 1.1 1.07 – 1.13 8.18e-12 6025 68192 exclusion phecode
276.1 Electrolyte imbalance Endocrine/metabolic 1.09 1.05 – 1.12 4.93e-06 3363 38240 exclusion phecode
276.11 Hyperosmolality and/or hypernatremia Endocrine/metabolic 1.1 0.949 – 1.28 0.2 186 2236 exclusion phecode
276.12 Hyposmolality and/or hyponatremia Endocrine/metabolic 1.07 1.02 – 1.13 0.0115 1580 17053 exclusion phecode
276.13 Hyperpotassemia Endocrine/metabolic 1.12 1.04 – 1.22 0.00447 644 9010 exclusion phecode
276.14 Hypopotassemia Endocrine/metabolic 1.09 1.03 – 1.16 0.0036 1250 13379 exclusion phecode
276.4 Acid-base balance disorder Endocrine/metabolic 1.14 1.06 – 1.22 0.00024 906 10866 exclusion phecode
276.41 Acidosis Endocrine/metabolic 1.14 1.06 – 1.22 0.000482 813 9862 exclusion phecode
276.42 Alkalosis Endocrine/metabolic 1.11 0.91 – 1.36 0.299 101 1053 exclusion phecode
276.5 Hypovolemia Endocrine/metabolic 1.11 1.06 – 1.16 1.74e-06 2355 26504 exclusion phecode
276.6 Fluid overload Endocrine/metabolic 1.13 1.01 – 1.26 0.0312 338 4228 exclusion phecode
276.8 Polydipsia Endocrine/metabolic 1.12 0.917 – 1.36 0.273 100 1224 exclusion phecode
277 Other disorders of metabolism Endocrine/metabolic 1.04 0.969 – 1.12 0.269 800 8467 exclusion phecode
277.4 Disorders of bilirubin excretion Endocrine/metabolic 1.06 0.952 – 1.19 0.269 331 3378 exclusion phecode
277.5 Other disorders of lipoid metabolism Endocrine/metabolic 1.03 0.881 – 1.2 0.737 176 2132 exclusion phecode
277.51 Lipoprotein disorders Endocrine/metabolic 0.784 0.575 – 1.07 0.124 38 483 exclusion phecode
278 Overweight, obesity and other hyperalimentation Endocrine/metabolic 1.25 1.23 – 1.28 7.51e-90 8569 102682 exclusion phecode
278.1 Obesity Endocrine/metabolic 1.26 1.23 – 1.29 1.67e-90 8433 101134 exclusion phecode
278.3 Localized adiposity Endocrine/metabolic 1.11 0.875 – 1.4 0.395 75 802 exclusion phecode
278.4 Abnormal weight gain Endocrine/metabolic 1.3 1 – 1.69 0.0464 52 627 exclusion phecode
279 Disorders involving the immune mechanism Endocrine/metabolic 0.961 0.84 – 1.1 0.562 233 2364 exclusion phecode
279.1 Immunity deficiency Endocrine/metabolic 0.97 0.836 – 1.13 0.686 194 1984 exclusion phecode
279.11 Deficiency of humoral immunity Endocrine/metabolic 0.887 0.738 – 1.07 0.199 131 1313 exclusion phecode
279.7 Other immunological findings Endocrine/metabolic 0.981 0.855 – 1.13 0.782 227 2290 exclusion phecode
280 Iron deficiency anemias Hematopoietic 1.06 1.03 – 1.09 1.32e-05 6465 72172 exclusion phecode
280.1
Iron deficiency anemias, unspecified or not due
Iron deficiency anemias, unspecified or not due to blood loss
 Hematopoietic 1.06 1.03 – 1.09 1.93e-05 6180 69311 exclusion phecode
280.2
Iron deficiency anemia secondary to blood loss
Iron deficiency anemia secondary to blood loss (chronic)
 Hematopoietic 1.08 0.978 – 1.2 0.127 422 4338 exclusion phecode
281 Other deficiency anemia Hematopoietic 1.08 1.01 – 1.15 0.028 932 10541 exclusion phecode
281.1 Megaloblastic anemia Hematopoietic 1.08 1.01 – 1.16 0.029 893 10104 exclusion phecode
281.11 Pernicious anemia Hematopoietic 1.1 1.02 – 1.2 0.0202 618 7120 exclusion phecode
281.12 Other vitamin B12 deficiency anemia Hematopoietic 1.12 0.948 – 1.32 0.183 149 1678 exclusion phecode
281.13 Folate-deficiency anemia Hematopoietic 1.03 0.878 – 1.22 0.688 161 1725 exclusion phecode
281.9 Deficiency anemias Hematopoietic 1.01 0.746 – 1.38 0.934 46 514 exclusion phecode
282 Hereditary hemolytic anemias Hematopoietic 1.18 0.996 – 1.4 0.0553 133 1422 exclusion phecode
282.8 Other hemoglobinopathies Hematopoietic 1.17 0.903 – 1.53 0.23 51 531 exclusion phecode
282.9 Other hereditary hemolytic anemias Hematopoietic 1.04 0.816 – 1.32 0.767 72 809 exclusion phecode
283 Acquired hemolytic anemias Hematopoietic 1.08 0.891 – 1.31 0.432 117 1290 exclusion phecode
283.1 Autoimmune hemolytic anemias Hematopoietic 1.1 0.889 – 1.36 0.377 89 996 exclusion phecode
284 Aplastic anemia Hematopoietic 1.04 0.937 – 1.16 0.449 379 4117 exclusion phecode
285 Other anemias Hematopoietic 1.04 1.02 – 1.06 0.000105 10456 114585 exclusion phecode
285.1 Acute posthemorrhagic anemia Hematopoietic 1.01 0.892 – 1.15 0.87 253 2590 exclusion phecode
285.2 Anemia of chronic disease Hematopoietic 1 0.919 – 1.09 0.967 573 6568 exclusion phecode
285.22 Anemia in neoplastic disease Hematopoietic 0.993 0.893 – 1.11 0.904 381 3904 exclusion phecode
286 Coagulation defects Hematopoietic 1.05 0.978 – 1.13 0.179 825 8736 exclusion phecode
286.1 Congenital coagulation defects Hematopoietic 1.08 0.98 – 1.2 0.117 416 4369 exclusion phecode
286.11 Von willebrand's disease Hematopoietic 1.09 0.883 – 1.35 0.414 91 918 exclusion phecode
286.12
Congenital deficiency of other clotting factors
Congenital deficiency of other clotting factors (including factor VII)
 Hematopoietic 1.08 0.95 – 1.23 0.24 261 2795 exclusion phecode
286.13 Congenital factor VIII disorder Hematopoietic 1.15 0.878 – 1.51 0.311 55 597 exclusion phecode
286.5
Hemorrhagic disorder due to intrinsic
Hemorrhagic disorder due to intrinsic circulating anticoagulants
 Hematopoietic 0.945 0.748 – 1.19 0.635 72 797 exclusion phecode
286.7 Other and unspecified coagulation defects Hematopoietic 1.02 0.914 – 1.14 0.707 346 3660 exclusion phecode
287 Purpura and other hemorrhagic conditions Hematopoietic 1.05 0.991 – 1.1 0.106 1469 15512 exclusion phecode
287.1 Spontaneous ecchymoses Hematopoietic 1.08 0.893 – 1.31 0.422 111 1211 exclusion phecode
287.2 Allergic purpura Hematopoietic 0.974 0.71 – 1.34 0.869 45 486 exclusion phecode
287.3 Thrombocytopenia Hematopoietic 1.03 0.977 – 1.09 0.254 1383 14596 exclusion phecode
287.31 Primary thrombocytopenia Hematopoietic 1.08 0.974 – 1.21 0.141 374 3961 exclusion phecode
287.32 Secondary thrombocytopenia Hematopoietic 0.918 0.704 – 1.2 0.53 65 710 exclusion phecode
288 Diseases of white blood cells Hematopoietic 1.02 0.986 – 1.06 0.243 3503 35525 exclusion phecode
288.1 Decreased white blood cell count Hematopoietic 1.02 0.98 – 1.06 0.352 2964 29932 exclusion phecode
288.11 Neutropenia Hematopoietic 1.02 0.981 – 1.06 0.349 2971 30014 exclusion phecode
288.3 Eosinophilia Hematopoietic 0.974 0.753 – 1.26 0.842 62 663 exclusion phecode
289 Other diseases of blood and blood-forming organs Hematopoietic 1 0.931 – 1.08 0.968 774 8112 exclusion phecode
289.3
Personal history of diseases of blood and
Personal history of diseases of blood and blood-forming organs
 Hematopoietic 0.988 0.869 – 1.12 0.857 259 2760 exclusion phecode
289.4 Lymphadenitis Hematopoietic 1.02 0.975 – 1.06 0.44 2355 24586 exclusion phecode
289.5 Diseases of spleen Hematopoietic 1.03 0.933 – 1.14 0.563 434 4831 exclusion phecode
289.8 Polycythemia, secondary Hematopoietic 1.07 0.944 – 1.22 0.283 254 2705 exclusion phecode
289.9 Abnormality of red blood cells Hematopoietic 1.12 0.878 – 1.42 0.368 76 842 exclusion phecode
290
Delirium dementia and amnestic and other
Delirium dementia and amnestic and other cognitive disorders
 Mental Disorders 1.02 0.974 – 1.08 0.353 1641 17903 exclusion phecode
290.1 Dementias Mental Disorders 1.03 0.957 – 1.1 0.464 857 9276 exclusion phecode
290.11 Alzheimer's disease Mental Disorders 1.05 0.943 – 1.16 0.391 386 3981 exclusion phecode
290.16 Vascular dementia Mental Disorders 1.02 0.867 – 1.21 0.776 152 1848 exclusion phecode
290.2 Delirium due to conditions classified elsewhere Mental Disorders 1.03 0.947 – 1.13 0.449 539 6035 exclusion phecode
290.3
Other persistent mental disorders due to
Other persistent mental disorders due to conditions classified elsewhere
 Mental Disorders 0.907 0.713 – 1.15 0.427 66 689 exclusion phecode
291
Other specified nonpsychotic and/or transient
Other specified nonpsychotic and/or transient mental disorders
 Mental Disorders 1.02 0.947 – 1.1 0.563 722 7929 exclusion phecode
291.1
Transient mental disorders due to conditions
Transient mental disorders due to conditions classified elsewhere
 Mental Disorders 0.893 0.736 – 1.08 0.253 113 1266 exclusion phecode
291.4
Specific nonpsychotic mental disorders due to
Specific nonpsychotic mental disorders due to brain damage
 Mental Disorders 0.992 0.872 – 1.13 0.905 252 2680 exclusion phecode
291.8 Alteration of consciousness Mental Disorders 1.1 0.992 – 1.22 0.0714 373 4141 exclusion phecode
292 Neurological disorders Mental Disorders 1.04 1.01 – 1.08 0.0128 3987 43204 exclusion phecode
292.1 Aphasia/speech disturbance Mental Disorders 1.1 1.04 – 1.16 0.00131 1287 14150 exclusion phecode
292.2 Mild cognitive impairment Mental Disorders 0.954 0.809 – 1.13 0.579 159 1770 exclusion phecode
292.3 Memory loss Mental Disorders 1.01 0.929 – 1.09 0.876 644 6520 exclusion phecode
292.4 Altered mental status Mental Disorders 1 0.957 – 1.05 0.879 1820 20305 exclusion phecode
292.6 Hallucinations Mental Disorders 1.11 0.978 – 1.25 0.107 269 2892 exclusion phecode
293 Symptoms involving head and neck Mental Disorders 1.02 0.977 – 1.07 0.318 1873 19540 exclusion phecode
293.1
Swelling, mass, or lump in head and neck
Swelling, mass, or lump in head and neck [Space-occupying lesion, intracranial NOS]
 Mental Disorders 1.06 0.986 – 1.14 0.114 831 8486 exclusion phecode
295 Schizophrenia and other psychotic disorders Mental Disorders 0.991 0.918 – 1.07 0.821 730 8042 exclusion phecode
295.1 Schizophrenia Mental Disorders 0.956 0.871 – 1.05 0.34 495 5507 exclusion phecode
295.2 Paranoid disorders Mental Disorders 1.11 0.937 – 1.32 0.224 152 1690 exclusion phecode
295.3 Psychosis Mental Disorders 1.01 0.863 – 1.19 0.873 155 1622 exclusion phecode
296 Mood disorders Mental Disorders 1.08 1.06 – 1.1 6.98e-14 11154 118283 exclusion phecode
296.1 Bipolar Mental Disorders 0.932 0.871 – 0.996 0.0385 949 10113 exclusion phecode
296.2 Depression Mental Disorders 1.09 1.07 – 1.11 4.19e-17 10575 112246 exclusion phecode
296.22 Major depressive disorder Mental Disorders 1.05 0.934 – 1.18 0.422 317 3450 exclusion phecode
297.2 Suicide or self-inflicted injury Mental Disorders 1.1 0.973 – 1.24 0.128 276 2948 exclusion phecode
300 Anxiety disorders Mental Disorders 1.09 1.06 – 1.11 3.89e-10 6285 65322 exclusion phecode
300.1 Anxiety disorder Mental Disorders 1.09 1.06 – 1.12 1.13e-09 5813 60361 exclusion phecode
300.11 Generalized anxiety disorder Mental Disorders 1.02 0.853 – 1.21 0.865 137 1422 exclusion phecode
300.12 Agorophobia, social phobia, and panic disorder Mental Disorders 1.08 1 – 1.17 0.0479 650 6752 exclusion phecode
300.13 Phobia Mental Disorders 1.1 1 – 1.21 0.0421 453 4783 exclusion phecode
300.3 Obsessive-compulsive disorders Mental Disorders 1.15 0.961 – 1.37 0.128 131 1352 exclusion phecode
300.4 Dysthymic disorder Mental Disorders 1.36 1.02 – 1.82 0.0387 47 498 exclusion phecode
300.8 Acute reaction to stress Mental Disorders 1.31 1.08 – 1.58 0.00517 112 1186 exclusion phecode
300.9 Posttraumatic stress disorder Mental Disorders 1.16 0.944 – 1.42 0.157 102 1082 exclusion phecode
301 Personality disorders Mental Disorders 1.13 1 – 1.28 0.0433 276 3211 exclusion phecode
301.2 Antisocial/borderline personality disorder Mental Disorders 1.13 0.927 – 1.37 0.233 100 1151 exclusion phecode
302 Sexual and gender identity disorders Mental Disorders 1.17 1.02 – 1.34 0.0211 231 2630 exclusion phecode
303 Psychogenic and somatoform disorders Mental Disorders 0.985 0.893 – 1.09 0.756 437 4460 exclusion phecode
303.3 Psychogenic disorder Mental Disorders 0.973 0.869 – 1.09 0.64 333 3341 exclusion phecode
303.4 Somatoform disorder Mental Disorders 1.13 0.94 – 1.36 0.19 110 1186 exclusion phecode
304 Adjustment reaction Mental Disorders 1.05 0.925 – 1.18 0.477 263 2829 exclusion phecode
305.2 Eating disorder Mental Disorders 1.06 0.838 – 1.33 0.641 80 868 exclusion phecode
306 Other mental disorder Mental Disorders 1.11 1.1 – 1.13 1.16e-57 24886 217816 exclusion phecode
306.9 Tension headache Mental Disorders 1.11 0.983 – 1.25 0.093 289 3047 exclusion phecode
313 Pervasive developmental disorders Mental Disorders 0.863 0.674 – 1.1 0.241 63 732 exclusion phecode
313.3 Autism Mental Disorders 0.794 0.596 – 1.06 0.117 42 511 exclusion phecode
315 Develomental delays and disorders Mental Disorders 1.14 1.02 – 1.29 0.0252 302 3293 exclusion phecode
315.1 Learning disorder Mental Disorders 1.07 0.892 – 1.29 0.454 125 1539 exclusion phecode
315.2 Speech and language disorder Mental Disorders 1.03 0.81 – 1.31 0.815 76 806 exclusion phecode
316 Substance addiction and disorders Mental Disorders 1.1 1.07 – 1.14 4.96e-11 4802 50004 exclusion phecode
316.1 Polyneuropathy due to drugs Mental Disorders 1.26 0.975 – 1.64 0.0771 55 568 exclusion phecode
317 Alcohol-related disorders Mental Disorders 1.09 1.07 – 1.11 1.64e-18 11642 119575 exclusion phecode
317.1 Alcoholism Mental Disorders 1.08 1.06 – 1.11 7.94e-12 8145 83748 exclusion phecode
317.11 Alcoholic liver damage Mental Disorders 1.14 1.06 – 1.24 0.000864 674 7891 exclusion phecode
318 Tobacco use disorder Mental Disorders 1.15 1.13 – 1.16 4.89e-66 17504 175090 exclusion phecode
320 Meningitis Neurological 1.1 0.992 – 1.22 0.071 413 4228 exclusion phecode
323 Encephalitis Neurological 0.99 0.883 – 1.11 0.855 320 3246 exclusion phecode
323.2 Acute (transverse) myelitis Neurological 0.807 0.631 – 1.03 0.0879 69 704 exclusion phecode
324 Other CNS infection and poliomyelitis Neurological 1.09 0.962 – 1.24 0.176 265 2741 exclusion phecode
327 Sleep disorders Neurological 1.06 0.996 – 1.13 0.0648 991 10938 exclusion phecode
327.3 Sleep apnea Neurological 1.19 1.15 – 1.23 2.19e-23 3577 41582 exclusion phecode
327.4 Insomnia Neurological 1.01 0.855 – 1.2 0.893 147 1575 exclusion phecode
327.41 Organic or persistent insomnia Neurological 1.04 0.872 – 1.25 0.636 125 1325 exclusion phecode
331 Other cerebral degenerations Neurological 1.04 0.973 – 1.11 0.256 1005 10696 exclusion phecode
331.1 Hydrocephalus Neurological 1.02 0.93 – 1.12 0.646 464 4760 exclusion phecode
331.9 Cerebral degeneration, unspecified Neurological 1.02 0.919 – 1.14 0.684 356 4011 exclusion phecode
332 Parkinson's disease Neurological 0.979 0.919 – 1.04 0.526 1036 10429 exclusion phecode
333
Extrapyramidal disease and abnormal movement
Extrapyramidal disease and abnormal movement disorders
 Neurological 1.07 0.994 – 1.15 0.0732 802 8440 exclusion phecode
333.1 Essential tremor Neurological 1.04 0.891 – 1.21 0.645 187 2008 exclusion phecode
333.2 Myoclonus Neurological 1.36 1.1 – 1.69 0.00511 86 910 exclusion phecode
333.4 Torsion dystonia Neurological 1.06 0.931 – 1.22 0.36 233 2398 exclusion phecode
334 Degenerative disease of the spinal cord Neurological 1.11 1.06 – 1.17 3.02e-05 1634 17019 exclusion phecode
334.1 Spinocerebellar disease Neurological 1.05 0.859 – 1.29 0.622 107 1105 exclusion phecode
334.2 Anterior horn cell disease Neurological 0.992 0.862 – 1.14 0.914 221 2292 exclusion phecode
335 Multiple sclerosis Neurological 0.954 0.9 – 1.01 0.112 1260 12798 exclusion phecode
337 Disorders of the autonomic nervous system Neurological 1.18 1.03 – 1.35 0.0177 228 2499 exclusion phecode
337.1 Peripheral autonomic neuropathy Neurological 0.966 0.731 – 1.28 0.809 59 669 exclusion phecode
338 Pain Neurological 1.17 1.09 – 1.27 4.69e-05 699 7279 exclusion phecode
338.1 Acute pain Neurological 1.24 1.11 – 1.38 0.000164 356 3713 exclusion phecode
338.2 Chronic pain Neurological 1.14 1.02 – 1.27 0.0163 349 3627 exclusion phecode
339 Other headache syndromes Neurological 1.11 1.08 – 1.14 2.75e-17 7225 74386 exclusion phecode
340 Migraine Neurological 1.03 0.993 – 1.07 0.111 2697 27382 exclusion phecode
340.1 Migrain with aura Neurological 0.955 0.826 – 1.1 0.528 200 2024 exclusion phecode
341
Other demyelinating diseases of central nervous
Other demyelinating diseases of central nervous system
 Neurological 0.959 0.839 – 1.1 0.543 234 2434 exclusion phecode
342 Hemiplegia Neurological 1.14 1.08 – 1.21 3.71e-06 1275 14011 exclusion phecode
343 Infantile cerebral palsy Neurological 1.03 0.865 – 1.23 0.745 132 1366 exclusion phecode
344 Other paralytic syndromes Neurological 1.15 1.06 – 1.25 0.000874 590 6208 exclusion phecode
345 Epilepsy, recurrent seizures, convulsions Neurological 1.05 1.02 – 1.08 0.00116 4610 47531 exclusion phecode
345.1 Epilepsy Neurological 1.05 0.975 – 1.13 0.2 791 8226 exclusion phecode
345.11 Generalized convulsive epilepsy Neurological 1.1 0.993 – 1.22 0.0676 395 4182 exclusion phecode
345.12 Partial epilepsy Neurological 1.01 0.893 – 1.15 0.837 259 2640 exclusion phecode
345.3 Convulsions Neurological 1.03 0.988 – 1.08 0.151 2042 21119 exclusion phecode
346.1
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of skull and head
 Neurological 1.22 1.02 – 1.46 0.0267 127 1338 exclusion phecode
348 Other conditions of brain Neurological 1.17 1.08 – 1.27 0.000101 678 7378 exclusion phecode
348.2 Cerebral edema and compression of brain Neurological 1.19 1.04 – 1.35 0.0125 238 2553 exclusion phecode
348.4 Cerebral cysts Neurological 1.06 0.88 – 1.27 0.55 120 1284 exclusion phecode
348.7 Coma Neurological 1.05 0.94 – 1.18 0.37 330 3373 exclusion phecode
348.8 Encephalopathy, not elsewhere classified Neurological 1.18 1.03 – 1.36 0.0171 208 2345 exclusion phecode
348.9 Other conditions of brain, NOS Neurological 1.05 0.943 – 1.18 0.357 346 3702 exclusion phecode
349
Other and unspecified disorders of the nervous
Other and unspecified disorders of the nervous system
 Neurological 1.04 0.926 – 1.17 0.496 302 3234 exclusion phecode
350 Abnormal movement Neurological 1.07 1.03 – 1.12 0.00103 2322 25008 exclusion phecode
350.1 Abnormal involuntary movements Neurological 1.09 1.01 – 1.17 0.0223 799 8332 exclusion phecode
350.2 Abnormality of gait Neurological 1.06 0.999 – 1.12 0.0554 1358 14903 exclusion phecode
350.3 Lack of coordination Neurological 1.16 1.04 – 1.3 0.00981 316 3416 exclusion phecode
350.6 Disturbances of sensation of smell and taste Neurological 1.14 0.843 – 1.53 0.403 50 508 exclusion phecode
351 Other peripheral nerve disorders Neurological 1.13 1.11 – 1.15 1.66e-34 11191 118192 exclusion phecode
352 Disorders of other cranial nerves Neurological 1.16 1.09 – 1.23 6.25e-07 1234 12993 exclusion phecode
352.1 Trigeminal nerve disorders [CN5] Neurological 1.15 1.04 – 1.27 0.00498 435 4427 exclusion phecode
352.2 Facial nerve disorders [CN7] Neurological 1.18 1.09 – 1.27 1.57e-05 776 8326 exclusion phecode
353 Nerve root and plexus disorders Neurological 1.16 1.09 – 1.23 4.39e-06 1036 10700 exclusion phecode
353.1 Nerve plexus lesions Neurological 1.11 0.912 – 1.35 0.3 109 1084 exclusion phecode
353.2 Nerve root lesions Neurological 1.45 1.07 – 1.95 0.0149 52 533 exclusion phecode
356 Hereditary and idiopathic peripheral neuropathy Neurological 0.911 0.759 – 1.09 0.313 137 1416 exclusion phecode
357 Inflammatory and toxic neuropathy Neurological 1.15 1.08 – 1.22 1.75e-05 1068 12730 exclusion phecode
358 Myoneural disorders Neurological 1.04 0.898 – 1.21 0.589 190 1980 exclusion phecode
358.1 Myasthenia gravis Neurological 1.07 0.916 – 1.25 0.389 172 1804 exclusion phecode
359 Muscular dystrophies and other myopathies Neurological 1.17 1.05 – 1.29 0.00281 400 4400 exclusion phecode
359.1 Muscular dystrophies Neurological 1.15 0.95 – 1.38 0.155 116 1151 exclusion phecode
359.2 Myopathy Neurological 1.19 1.06 – 1.34 0.00392 299 3404 exclusion phecode
360 Disorders of the globe Sense Organs 1.01 0.899 – 1.14 0.857 312 3184 exclusion phecode
360.2 Progressive myopia Sense Organs 1 0.875 – 1.15 0.984 235 2374 exclusion phecode
361 Retinal detachments and defects Sense Organs 0.979 0.943 – 1.02 0.27 3031 30390 exclusion phecode
361.1 Retinal detachment with retinal defect Sense Organs 0.989 0.934 – 1.05 0.708 1306 13014 exclusion phecode
361.2 Retinoschisis and retinal cysts Sense Organs 0.863 0.664 – 1.12 0.274 60 639 exclusion phecode
362 Other retinal disorders Sense Organs 1.01 0.979 – 1.05 0.421 3251 35990 exclusion phecode
362.2
Degeneration of macula and posterior pole of
Degeneration of macula and posterior pole of retina
 Sense Organs 0.985 0.939 – 1.03 0.521 1902 20471 exclusion phecode
362.29 Macular degeneration (senile) of retina NOS Sense Organs 0.985 0.94 – 1.03 0.529 1900 20441 exclusion phecode
362.3 Other nondiabetic retinopathy Sense Organs 1.11 0.919 – 1.34 0.281 127 1516 exclusion phecode
362.31 Separation of retinal layers Sense Organs 1.1 0.887 – 1.37 0.379 92 926 exclusion phecode
362.4 Retinal vascular changes and abnomalities Sense Organs 1.06 0.985 – 1.15 0.116 700 7915 exclusion phecode
362.6 Peripheral retinal degenerations Sense Organs 0.928 0.794 – 1.08 0.345 166 1712 exclusion phecode
362.7 Hereditary retinal dystrophies Sense Organs 1.16 0.922 – 1.46 0.203 79 773 exclusion phecode
362.8 Retinal hemorrhage/ischemia Sense Organs 1.14 0.929 – 1.39 0.215 102 1090 exclusion phecode
363
Chorioretinal inflammations, scars, and other
Chorioretinal inflammations, scars, and other disorders of choroid
 Sense Organs 0.867 0.732 – 1.03 0.0997 150 1614 exclusion phecode
363.3 Chorioretinal scars Sense Organs 0.738 0.553 – 0.984 0.0385 53 661 exclusion phecode
364 Corneal opacity and other disorders of cornea Sense Organs 0.969 0.889 – 1.06 0.48 587 6070 exclusion phecode
364.1 Corneal opacity Sense Organs 1.14 0.908 – 1.42 0.262 81 847 exclusion phecode
364.2 Corneal edema Sense Organs 1.08 0.846 – 1.37 0.544 71 741 exclusion phecode
364.4 Corneal degenerations Sense Organs 1.07 0.914 – 1.25 0.398 173 1891 exclusion phecode
364.41 Keratoconus Sense Organs 1.05 0.836 – 1.32 0.681 81 824 exclusion phecode
364.5 Corneal dystrophy Sense Organs 0.848 0.731 – 0.983 0.0291 198 1990 exclusion phecode
364.9 Cornea replaced by transplant Sense Organs 0.947 0.77 – 1.16 0.605 93 939 exclusion phecode
365 Glaucoma Sense Organs 1.04 1.01 – 1.08 0.00857 3986 41133 exclusion phecode
365.1 Open-angle glaucoma Sense Organs 1.03 0.967 – 1.11 0.329 938 9624 exclusion phecode
365.11 Primary open angle glaucoma Sense Organs 1.03 0.965 – 1.1 0.353 932 9574 exclusion phecode
365.2 Primary angle-closure glaucoma Sense Organs 0.95 0.876 – 1.03 0.209 649 6579 exclusion phecode
366 Cataract Sense Organs 1.04 1.02 – 1.06 9.94e-07 17642 158330 exclusion phecode
366.1 Nonsenile Cataract Sense Organs 1.05 0.819 – 1.35 0.694 65 669 exclusion phecode
366.2 Senile cataract Sense Organs 1.04 1.02 – 1.07 0.000549 7293 76693 exclusion phecode
366.3 Traumatic cataract Sense Organs 0.98 0.799 – 1.2 0.847 94 928 exclusion phecode
367
Disorders of refraction and accommodation
Disorders of refraction and accommodation; blindness and low vision
 Sense Organs 1.02 0.978 – 1.07 0.336 2194 22670 exclusion phecode
367.1 Myopia Sense Organs 1.01 0.951 – 1.07 0.733 1159 11766 exclusion phecode
367.2 Astigmatism Sense Organs 0.994 0.849 – 1.16 0.942 178 1793 exclusion phecode
367.8 Hypermetropia Sense Organs 0.967 0.844 – 1.11 0.629 241 2395 exclusion phecode
367.9 Blindness and low vision Sense Organs 1.09 1 – 1.18 0.0512 616 6764 exclusion phecode
368 Visual disturbances Sense Organs 1.06 1.02 – 1.11 0.00227 2668 27947 exclusion phecode
368.1 Amblyopia Sense Organs 0.948 0.862 – 1.04 0.27 465 4962 exclusion phecode
368.2 Diplopia and disorders of binocular vision Sense Organs 1.1 1.01 – 1.19 0.0251 658 6893 exclusion phecode
368.3 Anisometropia Sense Organs 1.11 0.935 – 1.32 0.234 145 1440 exclusion phecode
368.4 Visual field defects Sense Organs 1.03 0.91 – 1.16 0.655 288 3118 exclusion phecode
368.9 Subjective visual disturbances Sense Organs 1.12 1.03 – 1.22 0.0117 559 5794 exclusion phecode
369 Infection of the eye Sense Organs 0.978 0.893 – 1.07 0.627 508 5221 exclusion phecode
369.2 Eye infection, viral Sense Organs 0.871 0.722 – 1.05 0.148 117 1175 exclusion phecode
369.5 Conjunctivitis, infectious Sense Organs 0.969 0.838 – 1.12 0.669 194 2013 exclusion phecode
370 Keratitis Sense Organs 0.948 0.833 – 1.08 0.422 255 2702 exclusion phecode
370.1 Corneal ulcer Sense Organs 0.893 0.746 – 1.07 0.22 127 1334 exclusion phecode
371 Inflammation of the eye Sense Organs 0.999 0.961 – 1.04 0.97 2863 28793 exclusion phecode
371.1 Uveitis, noninfectious or NOS Sense Organs 0.982 0.89 – 1.08 0.715 436 4569 exclusion phecode
371.3 Inflammation of eyelids Sense Organs 0.996 0.953 – 1.04 0.848 2236 22240 exclusion phecode
372 Disorders of conjunctiva Sense Organs 1.04 0.958 – 1.12 0.381 707 7142 exclusion phecode
374 Other disorders of eyelids Sense Organs 1.06 1.03 – 1.09 2.73e-05 5212 53459 exclusion phecode
374.1 Ectropion or entropion Sense Organs 1.09 1.02 – 1.16 0.0101 951 9879 exclusion phecode
374.3 Ptosis of eyelid Sense Organs 1.06 1.01 – 1.11 0.0278 1675 17171 exclusion phecode
375 Disorders of lacrimal system Sense Organs 1.05 1.01 – 1.1 0.0277 2031 20754 exclusion phecode
375.2 Epiphora Sense Organs 1.03 0.956 – 1.1 0.48 826 8400 exclusion phecode
376 Disorders of the orbit Sense Organs 0.848 0.675 – 1.06 0.156 78 807 exclusion phecode
377 Disorders of optic nerve and visual pathways Sense Organs 1.12 1 – 1.26 0.0459 327 3423 exclusion phecode
377.1 Optic atrophy Sense Organs 1.17 0.874 – 1.57 0.291 50 535 exclusion phecode
377.3 Optic neuritis/neuropathy Sense Organs 1.11 0.918 – 1.35 0.274 115 1197 exclusion phecode
378
Strabismus and other disorders of binocular eye
Strabismus and other disorders of binocular eye movements
 Sense Organs 1.02 0.965 – 1.08 0.468 1294 13387 exclusion phecode
378.1 Strabismus (not specified as paralytic) Sense Organs 1.03 0.958 – 1.1 0.437 854 8629 exclusion phecode
378.2 Nystagmus and other irregular eye movements Sense Organs 1.05 0.902 – 1.21 0.555 188 2006 exclusion phecode
378.5 Paralytic strabismus Sense Organs 0.984 0.864 – 1.12 0.814 243 2625 exclusion phecode
379 Other disorders of eye Sense Organs 1.04 1 – 1.08 0.0506 3229 34624 exclusion phecode
379.2 Disorders of vitreous body Sense Organs 1.02 0.958 – 1.08 0.57 1155 12781 exclusion phecode
379.3 Aphakia and other disorders of lens Sense Organs 1.07 1.01 – 1.12 0.0147 1597 16868 exclusion phecode
379.4 Anomalies of pupillary function Sense Organs 1.17 0.912 – 1.51 0.214 69 668 exclusion phecode
379.5 Disorders of iris and ciliary body Sense Organs 0.946 0.85 – 1.05 0.3 357 3776 exclusion phecode
379.9 Pain, swelling or discharge of eye Sense Organs 1.02 0.868 – 1.21 0.786 150 1609 exclusion phecode
380 Disorders of external ear Sense Organs 1.04 0.959 – 1.14 0.327 581 6004 exclusion phecode
380.1 Otitis externa Sense Organs 1.11 1.01 – 1.22 0.0341 439 4850 exclusion phecode
380.4 Impacted cerumen Sense Organs 1.09 0.974 – 1.22 0.133 332 3387 exclusion phecode
381 Otitis media and Eustachian tube disorders Sense Organs 1.11 1.06 – 1.17 5.6e-06 1970 20237 exclusion phecode
381.1 Otitis media Sense Organs 1.14 1.08 – 1.2 1.21e-06 1609 16620 exclusion phecode
381.11 Suppurative and unspecified otitis media Sense Organs 1.16 1.08 – 1.25 9.57e-05 781 8014 exclusion phecode
381.2 Eustachian tube disorders Sense Organs 1.05 0.9 – 1.21 0.564 185 1831 exclusion phecode
381.3 Mastoiditis & related conditions Sense Organs 1.13 0.961 – 1.34 0.137 152 1613 exclusion phecode
381.9 Otorrhea Sense Organs 1.04 0.913 – 1.18 0.557 254 2647 exclusion phecode
382 Otalgia Sense Organs 1.01 0.897 – 1.14 0.844 286 2916 exclusion phecode
383 Otosclerosis Sense Organs 0.914 0.812 – 1.03 0.134 299 2952 exclusion phecode
384 Other disorders of tympanic membrane Sense Organs 1.16 1.1 – 1.23 6.02e-07 1212 12284 exclusion phecode
384.4 Perforation of tympanic membrane Sense Organs 1.18 1.11 – 1.26 5.89e-07 975 9877 exclusion phecode
385 Other disorders of middle ear and mastoid Sense Organs 1.17 1.08 – 1.26 6.74e-05 727 7369 exclusion phecode
385.3 Cholesteatoma Sense Organs 1.15 1.05 – 1.25 0.00212 562 5687 exclusion phecode
385.5
Tympanosclerosis and middle ear disease related
Tympanosclerosis and middle ear disease related to otitis media
 Sense Organs 1.18 1.02 – 1.36 0.0215 225 2279 exclusion phecode
386
Vertiginous syndromes and other disorders of
Vertiginous syndromes and other disorders of vestibular system
 Sense Organs 1.05 0.997 – 1.1 0.0655 1614 16424 exclusion phecode
386.1 Meniere's disease Sense Organs 1.05 0.962 – 1.15 0.276 544 5454 exclusion phecode
386.2 Peripheral or central vertigo Sense Organs 0.981 0.878 – 1.1 0.734 344 3533 exclusion phecode
386.3 Labyrinthitis Sense Organs 1.09 1.01 – 1.17 0.0321 708 7253 exclusion phecode
386.9
Dizziness and giddiness (Light-headedness and
Dizziness and giddiness (Light-headedness and vertigo)
 Sense Organs 1.09 1.05 – 1.12 1.4e-07 4162 43123 exclusion phecode
388 Other disorders of ear Sense Organs 0.976 0.839 – 1.14 0.755 186 1909 exclusion phecode
389 Hearing loss Sense Organs 1.08 1.05 – 1.12 4.96e-06 3771 39261 exclusion phecode
389.1 Sensorineural hearing loss Sense Organs 1.13 1.02 – 1.25 0.0188 408 4262 exclusion phecode
389.2 Conductive hearing loss Sense Organs 1.13 1.02 – 1.25 0.0179 416 4232 exclusion phecode
389.4 Tinnitus Sense Organs 1.08 0.985 – 1.19 0.1 479 4815 exclusion phecode
394 Rheumatic disease of the heart valves Circulatory System 1.05 1.02 – 1.09 0.000782 4358 45542 exclusion phecode
394.2 Mitral valve disease Circulatory System 1.04 1 – 1.08 0.0512 2682 27877 exclusion phecode
394.3 Aortic valve disease Circulatory System 1.09 1.03 – 1.16 0.00489 1134 11851 exclusion phecode
394.7 Disease of tricuspid valve Circulatory System 1.06 0.994 – 1.14 0.0729 929 9798 exclusion phecode
395 Heart valve disorders Circulatory System 1.06 1.03 – 1.1 0.000304 3742 39314 exclusion phecode
395.1 Nonrheumatic mitral valve disorders Circulatory System 1.05 1 – 1.09 0.0307 2588 26939 exclusion phecode
395.2 Nonrheumatic aortic valve disorders Circulatory System 1.09 0.954 – 1.25 0.2 229 2553 exclusion phecode
395.3 Nonrheumatic tricuspid valve disorders Circulatory System 1.11 0.891 – 1.38 0.356 89 963 exclusion phecode
395.4 Nonrheumatic pulmonary valve disorders Circulatory System 1.05 0.837 – 1.31 0.695 85 899 exclusion phecode
395.6 Heart valve replaced Circulatory System 1.1 1.04 – 1.16 0.00128 1308 13910 exclusion phecode
396 Abnormal heart sounds Circulatory System 1.1 1.03 – 1.18 0.00518 955 9935 exclusion phecode
401 Hypertension Circulatory System 1.19 1.18 – 1.2 4.89e-310 63455 258352 exclusion phecode
401.1 Essential hypertension Circulatory System 1.19 1.18 – 1.2 6.45e-310 63258 258135 exclusion phecode
401.2 Hypertensive heart and/or renal disease Circulatory System 1.21 1.14 – 1.28 4.71e-11 1356 18130 exclusion phecode
401.21 Hypertensive heart disease Circulatory System 1.23 1.09 – 1.38 0.000821 287 3498 exclusion phecode
401.22 Hypertensive chronic kidney disease Circulatory System 1.19 1.12 – 1.27 4.23e-08 1072 14761 exclusion phecode
401.3 Other hypertensive complications Circulatory System 1.12 0.924 – 1.35 0.252 121 1384 exclusion phecode
402
Elevated blood pressure reading without
Elevated blood pressure reading without diagnosis of hypertension
 Circulatory System 1.2 1.13 – 1.27 3.14e-10 1324 14232 exclusion phecode
411 Ischemic Heart Disease Circulatory System 1.16 1.14 – 1.17 1.05e-105 26474 199521 exclusion phecode
411.1 Unstable angina (intermediate coronary syndrome) Circulatory System 1.2 1.16 – 1.23 1.68e-28 4203 48355 exclusion phecode
411.2 Myocardial infarction Circulatory System 1.19 1.16 – 1.21 4.4e-60 10031 105611 exclusion phecode
411.3 Angina pectoris Circulatory System 1.17 1.15 – 1.19 3.14e-66 13082 135305 exclusion phecode
411.4 Coronary atherosclerosis Circulatory System 1.17 1.15 – 1.18 4.35e-79 17076 145560 exclusion phecode
411.41 Aneurysm and dissection of heart Circulatory System 1.03 0.949 – 1.11 0.491 654 6607 exclusion phecode
411.8
Other chronic ischemic heart disease
Other chronic ischemic heart disease, unspecified
 Circulatory System 1.19 1.16 – 1.21 3.86e-72 12341 123757 exclusion phecode
411.9
Other acute and subacute forms of ischemic
Other acute and subacute forms of ischemic heart disease
 Circulatory System 1.25 1.18 – 1.34 2.11e-12 1039 11418 exclusion phecode
414 Other forms of chronic heart disease Circulatory System 1.13 1.08 – 1.2 3.42e-06 1503 17064 exclusion phecode
414.2 ASCVD Circulatory System 1.09 0.836 – 1.42 0.526 56 673 exclusion phecode
415 Pulmonary heart disease Circulatory System 1.05 1.02 – 1.09 0.00259 4049 41907 exclusion phecode
415.11 Pulmonary embolism and infarction, acute Circulatory System 0.944 0.745 – 1.2 0.631 70 698 exclusion phecode
415.2 Chronic pulmonary heart disease Circulatory System 1.03 0.941 – 1.13 0.511 502 5580 exclusion phecode
415.21 Primary pulmonary hypertension Circulatory System 1.02 0.919 – 1.14 0.692 372 4175 exclusion phecode
416 Cardiomegaly Circulatory System 1.13 1.08 – 1.18 3.69e-08 2238 24840 exclusion phecode
418 Nonspecific chest pain Circulatory System 1.12 1.1 – 1.13 8.62e-63 25725 255784 exclusion phecode
418.1 Precordial pain Circulatory System 1.14 1.1 – 1.18 2.36e-12 3162 33658 exclusion phecode
420 Carditis Circulatory System 1.01 0.964 – 1.06 0.669 1865 19658 exclusion phecode
420.1 Myocarditis Circulatory System 0.985 0.812 – 1.19 0.878 121 1184 exclusion phecode
420.2 Pericarditis Circulatory System 1.01 0.951 – 1.07 0.766 1199 12513 exclusion phecode
420.21 Acute pericarditis Circulatory System 1.09 0.946 – 1.26 0.229 200 2095 exclusion phecode
420.22 Chronic pericarditis Circulatory System 1.07 0.875 – 1.3 0.527 102 1038 exclusion phecode
420.3 Endocarditis Circulatory System 1.05 0.965 – 1.14 0.268 621 6684 exclusion phecode
425 Cardiomyopathy Circulatory System 1.14 1.08 – 1.22 1.99e-05 1106 11797 exclusion phecode
425.1 Primary/intrinsic cardiomyopathies Circulatory System 1.15 1.08 – 1.23 8.95e-06 1076 11476 exclusion phecode
425.11 Hypertrophic obstructive cardiomyopathy Circulatory System 1.16 0.958 – 1.4 0.131 123 1239 exclusion phecode
425.12 Other hypertrophic cardiomyopathy Circulatory System 1.06 0.897 – 1.24 0.515 153 1515 exclusion phecode
425.8 Other cardiomyopathy Circulatory System 0.99 0.743 – 1.32 0.948 53 557 exclusion phecode
426 Cardiac conduction disorders Circulatory System 1.09 1.07 – 1.12 3.35e-11 5951 64423 exclusion phecode
426.2 Atrioventricular [AV] block Circulatory System 1.08 1.03 – 1.13 0.00278 1783 19598 exclusion phecode
426.21 First degree AV block Circulatory System 1.13 1.05 – 1.21 0.000962 824 9130 exclusion phecode
426.23 Second degree AV block Circulatory System 1.02 0.92 – 1.13 0.696 387 4169 exclusion phecode
426.24 Atrioventricular block, complete Circulatory System 1.09 0.99 – 1.19 0.0787 491 5429 exclusion phecode
426.25 Other heart block Circulatory System 1.03 0.861 – 1.24 0.72 121 1215 exclusion phecode
426.3 Bundle branch block Circulatory System 1.12 1.08 – 1.17 2.37e-09 2874 31064 exclusion phecode
426.31 Right bundle branch block Circulatory System 1.09 1.03 – 1.16 0.0022 1303 13843 exclusion phecode
426.32 Left bundle branch block Circulatory System 1.16 1.1 – 1.22 1.11e-07 1487 16322 exclusion phecode
426.4 Anomalous atrioventricular excitation Circulatory System 1.05 0.917 – 1.21 0.466 224 2201 exclusion phecode
426.8 Other cardiac conduction disorders Circulatory System 1.07 0.812 – 1.4 0.642 55 564 exclusion phecode
426.9 Cardiac pacemaker/device in situ Circulatory System 1.11 1.06 – 1.16 6.49e-06 2065 23036 exclusion phecode
426.91 Cardiac pacemaker in situ Circulatory System 1.11 1.06 – 1.16 1.84e-05 1901 21148 exclusion phecode
427 Cardiac dysrhythmias Circulatory System 1.06 1.04 – 1.07 2.19e-14 21632 193998 exclusion phecode
427.1 Paroxysmal tachycardia, unspecified Circulatory System 1.06 1.02 – 1.1 0.00542 2884 30138 exclusion phecode
427.11 Paroxysmal supraventricular tachycardia Circulatory System 1.03 0.985 – 1.08 0.197 2122 22187 exclusion phecode
427.12 Paroxysmal ventricular tachycardia Circulatory System 1.16 1.08 – 1.25 3.47e-05 828 8689 exclusion phecode
427.2 Atrial fibrillation and flutter Circulatory System 1.06 1.04 – 1.08 1.54e-09 12898 124582 exclusion phecode
427.3 Other specified cardiac dysrhythmias Circulatory System 1.09 1.05 – 1.13 4.29e-06 2910 30189 exclusion phecode
427.4 Cardiac arrest and ventricular fibrillation Circulatory System 1.1 1.03 – 1.17 0.0037 1038 11070 exclusion phecode
427.41 Ventricular fibrillation and flutter Circulatory System 1.09 0.972 – 1.23 0.138 306 3215 exclusion phecode
427.42 Cardiac arrest Circulatory System 1.12 1.04 – 1.2 0.00211 859 9182 exclusion phecode
427.5 Arrhythmia (cardiac) NOS Circulatory System 0.958 0.893 – 1.03 0.241 847 8931 exclusion phecode
427.6 Premature beats Circulatory System 1.08 0.987 – 1.19 0.0931 495 5046 exclusion phecode
427.61 Supraventricular premature beats Circulatory System 1.07 0.88 – 1.3 0.503 110 1092 exclusion phecode
427.7 Tachycardia NOS Circulatory System 1.08 1.03 – 1.13 0.00203 1922 20648 exclusion phecode
427.8 Sinoatrial node dysfunction (Bradycardia) Circulatory System 1.1 0.988 – 1.22 0.0816 372 3768 exclusion phecode
427.9 Palpitations Circulatory System 1.05 1.01 – 1.09 0.00526 3540 36229 exclusion phecode
428 Congestive heart failure; nonhypertensive Circulatory System 1.15 1.12 – 1.19 1.31e-19 4440 51854 exclusion phecode
428.1 Congestive heart failure (CHF) NOS Circulatory System 1.18 1.12 – 1.24 6.22e-10 1530 19540 exclusion phecode
428.2 Heart failure NOS Circulatory System 1.14 1.1 – 1.18 5.08e-14 3573 41209 exclusion phecode
429
Ill-defined descriptions and complications of
Ill-defined descriptions and complications of heart disease
 Circulatory System 1.07 0.988 – 1.16 0.0934 644 6769 exclusion phecode
429.1 Heart transplant/surgery Circulatory System 1.1 0.829 – 1.45 0.521 50 593 exclusion phecode
429.2 Abnormal function study of cardiovascular system Circulatory System 1.03 0.932 – 1.13 0.602 467 4932 exclusion phecode
429.3 Symptoms involving cardiovascular system Circulatory System 1.2 1.03 – 1.4 0.0209 178 1875 exclusion phecode
430 Intracranial hemorrhage Circulatory System 1.05 1 – 1.11 0.0364 1728 17643 exclusion phecode
430.1 Subarachnoid hemorrhage Circulatory System 1.04 0.971 – 1.12 0.241 792 7897 exclusion phecode
430.2 Intracerebral hemorrhage Circulatory System 1.04 0.96 – 1.12 0.342 682 7126 exclusion phecode
430.3 Subdural hemorrhage Circulatory System 1.04 0.909 – 1.18 0.596 245 2472 exclusion phecode
433 Cerebrovascular disease Circulatory System 1.1 1.08 – 1.13 1.23e-15 7542 81511 exclusion phecode
433.1 Occlusion and stenosis of precerebral arteries Circulatory System 1.19 1.12 – 1.27 5.95e-08 1002 10895 exclusion phecode
433.12 Cerebral atherosclerosis Circulatory System 1.23 1.06 – 1.42 0.00495 198 2083 exclusion phecode
433.2 Occlusion of cerebral arteries Circulatory System 1.11 1.07 – 1.15 1.94e-09 3595 39337 exclusion phecode
433.21
Cerebral artery occlusion, with cerebral
Cerebral artery occlusion, with cerebral infarction
 Circulatory System 1.16 1.1 – 1.23 7.86e-08 1398 15620 exclusion phecode
433.3 Cerebral ischemia Circulatory System 1.07 1.02 – 1.11 0.00213 2491 26988 exclusion phecode
433.31 Transient cerebral ischemia Circulatory System 1.07 1.02 – 1.13 0.00308 1841 19872 exclusion phecode
433.5 Cerebral aneurysm Circulatory System 1.03 0.922 – 1.14 0.636 375 3726 exclusion phecode
433.8 Late effects of cerebrovascular disease Circulatory System 1.14 1.07 – 1.21 4.51e-05 1067 11931 exclusion phecode
440 Atherosclerosis Circulatory System 1.21 1.14 – 1.29 1.73e-09 1071 12769 exclusion phecode
440.1 Atherosclerosis of renal artery Circulatory System 1.2 0.969 – 1.48 0.0952 93 1050 exclusion phecode
440.2 Atherosclerosis of the extremities Circulatory System 1.22 1.12 – 1.33 3.37e-06 585 7417 exclusion phecode
440.9 Atherosclerosis of aorta Circulatory System 1.23 1.08 – 1.41 0.00245 240 2683 exclusion phecode
441 Vascular insufficiency of intestine Circulatory System 1.1 1.01 – 1.2 0.0274 547 5781 exclusion phecode
441.1 Acute vascular insufficiency of intestine Circulatory System 1.04 0.914 – 1.18 0.58 251 2662 exclusion phecode
442 Other aneurysm Circulatory System 1.08 1.03 – 1.13 0.00284 1708 17490 exclusion phecode
442.1 Aortic aneurysm Circulatory System 1.08 1.02 – 1.14 0.00799 1319 13408 exclusion phecode
442.11 Abdominal aortic aneurysm Circulatory System 1.13 1.05 – 1.21 0.00117 820 8506 exclusion phecode
442.2 Aneurysm of iliac artery Circulatory System 1.22 0.995 – 1.5 0.0557 94 917 exclusion phecode
442.3 Aneurysm of artery of lower extremity Circulatory System 1.17 0.991 – 1.38 0.0635 146 1570 exclusion phecode
442.4 Arterial dissection Circulatory System 0.951 0.712 – 1.27 0.734 51 514 exclusion phecode
442.8 Aneurysm of other specified artery Circulatory System 1.01 0.87 – 1.18 0.866 185 1913 exclusion phecode
443 Peripheral vascular disease Circulatory System 1.16 1.12 – 1.2 1.42e-14 3006 36571 exclusion phecode
443.1 Raynaud's syndrome Circulatory System 1.05 0.986 – 1.12 0.129 1086 10870 exclusion phecode
443.7
Peripheral angiopathy in diseases classified
Peripheral angiopathy in diseases classified elsewhere
 Circulatory System 1.93 1.44 – 2.6 1.37e-05 41 3589 exclusion phecode
443.8 Other specified peripheral vascular diseases Circulatory System 1.15 1.11 – 1.2 1.55e-13 2974 34365 exclusion phecode
443.9 Peripheral vascular disease, unspecified Circulatory System 1.23 1.17 – 1.28 9.42e-18 1922 23831 exclusion phecode
444 Arterial embolism and thrombosis Circulatory System 1.25 1.16 – 1.35 5.97e-09 718 8610 exclusion phecode
444.1
Arterial embolism and thrombosis of lower
Arterial embolism and thrombosis of lower extremity artery
 Circulatory System 1.38 1.25 – 1.52 3.72e-10 406 5146 exclusion phecode
446 Polyarteritis nodosa and allied conditions Circulatory System 1.1 1.02 – 1.19 0.0119 741 7678 exclusion phecode
446.4 Wegener's granulomatosis Circulatory System 1.1 0.944 – 1.29 0.219 172 1723 exclusion phecode
446.5 Giant cell arteritis Circulatory System 1.04 0.931 – 1.15 0.514 357 3634 exclusion phecode
446.9 Arteritis NOS Circulatory System 1.15 1 – 1.32 0.0505 210 2248 exclusion phecode
447 Other disorders of arteries and arterioles Circulatory System 1.19 1.11 – 1.26 8.18e-08 1057 12339 exclusion phecode
447.1 Stricture of artery Circulatory System 1.27 1.17 – 1.37 3.96e-09 662 8034 exclusion phecode
448 Disease of capillaries Circulatory System 0.967 0.807 – 1.16 0.712 126 1350 exclusion phecode
450 Noninfectious disorders of lymphatic channels Circulatory System 1.04 0.961 – 1.13 0.311 622 6653 exclusion phecode
451 Phlebitis and thrombophlebitis Circulatory System 1.1 1.06 – 1.14 1.36e-07 3583 37235 exclusion phecode
451.2
Phlebitis and thrombophlebitis of lower
Phlebitis and thrombophlebitis of lower extremities
 Circulatory System 1.1 1.06 – 1.14 4.06e-07 3333 34673 exclusion phecode
452 Other venous embolism and thrombosis Circulatory System 1.03 0.946 – 1.13 0.456 504 5325 exclusion phecode
454 Varicose veins Circulatory System 1.01 0.988 – 1.03 0.459 10645 106214 exclusion phecode
454.1 Varicose veins of lower extremity Circulatory System 1 0.983 – 1.02 0.83 10991 109279 exclusion phecode
454.11 Varicose veins of lower extremity, symptomtic Circulatory System 0.954 0.874 – 1.04 0.292 559 5934 exclusion phecode
455 Hemorrhoids Circulatory System 1.03 1.02 – 1.05 1.01e-05 21963 221341 exclusion phecode
456 Chronic venous insufficiency [CVI] Circulatory System 0.917 0.78 – 1.08 0.296 157 1731 exclusion phecode
457
Encounter for long-term (current) use of
Encounter for long-term (current) use of anticoagulants, antithrombotics, aspirin
 Circulatory System 0.921 0.746 – 1.14 0.441 93 886 exclusion phecode
458 Hypotension Circulatory System 1.05 1.02 – 1.08 0.00214 5060 54226 exclusion phecode
458.1 Orthostatic hypotension Circulatory System 1.1 1.03 – 1.17 0.00288 1127 12541 exclusion phecode
458.2 Iatrogenic hypotension Circulatory System 1.05 0.914 – 1.22 0.471 203 2184 exclusion phecode
458.9 Hypotension NOS Circulatory System 1.05 1.01 – 1.09 0.0155 3061 32860 exclusion phecode
459 Other disorders of circulatory system Circulatory System 1.09 1.07 – 1.11 1.03e-22 14299 150891 exclusion phecode
459.1 Hemorrhage NOS Circulatory System 1.12 0.934 – 1.34 0.226 127 1317 exclusion phecode
459.9 Circulatory disease NEC Circulatory System 1.09 1.07 – 1.11 1.02e-23 14148 149588 exclusion phecode
464 Acute sinusitis Respiratory 1.2 1.03 – 1.39 0.0219 179 1865 exclusion phecode
465
Acute upper respiratory infections of multiple
Acute upper respiratory infections of multiple or unspecified sites
 Respiratory 1.1 1.05 – 1.15 6.01e-05 2081 21652 exclusion phecode
465.2 Acute pharyngitis Respiratory 1.11 1.03 – 1.2 0.00509 767 7913 exclusion phecode
465.4 Acute laryngitis and tracheitis Respiratory 1.14 0.969 – 1.34 0.112 155 1573 exclusion phecode
470 Septal Deviations/Turbinate Hypertrophy Respiratory 1.05 1.01 – 1.08 0.00471 4369 44045 exclusion phecode
471 Nasal polyps Respiratory 1.08 1.04 – 1.12 2.31e-05 3095 30910 exclusion phecode
472 Chronic pharyngitis and nasopharyngitis Respiratory 1.03 0.965 – 1.11 0.345 904 9064 exclusion phecode
473 Diseases of the larynx and vocal cords Respiratory 1.08 1.04 – 1.13 0.00026 2338 23998 exclusion phecode
473.1 Chronic laryngitis Respiratory 0.964 0.782 – 1.19 0.733 92 976 exclusion phecode
473.3 Paralysis/spasm of vocal cords or larynx Respiratory 1.07 0.939 – 1.22 0.308 239 2490 exclusion phecode
473.4 Voice disturbance Respiratory 1.04 0.975 – 1.11 0.22 975 10113 exclusion phecode
474 Acute and chronic tonsillitis Respiratory 1.08 1.03 – 1.14 0.00171 1679 16979 exclusion phecode
474.1 Acute tonsillitis Respiratory 1.1 1 – 1.2 0.0413 513 5287 exclusion phecode
474.2 Chronic tonsillitis and adenoiditis Respiratory 1.09 1.03 – 1.17 0.0047 1070 10754 exclusion phecode
475 Chronic sinusitis Respiratory 1.07 1.03 – 1.12 0.00111 2423 24482 exclusion phecode
476 Allergic rhinitis Respiratory 1 0.941 – 1.07 0.887 994 10060 exclusion phecode
477 Epistaxis or throat hemorrhage Respiratory 1.06 1.01 – 1.11 0.0102 2190 22832 exclusion phecode
478 Throat pain Respiratory 1.01 0.906 – 1.13 0.857 351 3573 exclusion phecode
479 Other upper respiratory disease Respiratory 1.08 1.04 – 1.11 1.44e-05 3780 38512 exclusion phecode
480 Pneumonia Respiratory 1.05 1.03 – 1.08 2.43e-06 9060 96649 exclusion phecode
480.1 Bacterial pneumonia Respiratory 1.04 1.01 – 1.06 0.00976 5822 62035 exclusion phecode
480.11 Pneumococcal pneumonia Respiratory 1.03 0.998 – 1.06 0.0702 5175 54956 exclusion phecode
480.12 Pseudomonal pneumonia Respiratory 1.4 1.14 – 1.73 0.00151 84 854 exclusion phecode
480.2 Viral pneumonia Respiratory 1.17 0.922 – 1.49 0.194 67 677 exclusion phecode
480.3 Pneumonia due to fungus (mycoses) Respiratory 1.18 0.948 – 1.47 0.138 91 921 exclusion phecode
480.5 Bronchopneumonia and lung abscess Respiratory 1.05 0.97 – 1.13 0.234 686 7400 exclusion phecode
481 Influenza Respiratory 1.03 0.917 – 1.15 0.628 310 3102 exclusion phecode
483 Acute bronchitis and bronchiolitis Respiratory 1.26 1.08 – 1.48 0.00347 170 1806 exclusion phecode
495 Asthma Respiratory 1.12 1.1 – 1.13 4.13e-59 23495 237944 exclusion phecode
495.2 Asthma with exacerbation Respiratory 1.16 1.01 – 1.33 0.0322 218 2384 exclusion phecode
496 Chronic airway obstruction Respiratory 1.16 1.14 – 1.19 5.12e-43 9132 94825 exclusion phecode
496.1 Emphysema Respiratory 1.16 1.1 – 1.22 4.59e-08 1565 16169 exclusion phecode
496.2 Chronic bronchitis Respiratory 1.18 1.13 – 1.22 5.83e-15 2544 27371 exclusion phecode
496.21 Obstructive chronic bronchitis Respiratory 1.18 1.13 – 1.23 3.54e-14 2340 25095 exclusion phecode
496.3 Bronchiectasis Respiratory 1.07 1.02 – 1.13 0.0044 1737 17711 exclusion phecode
497 Bronchitis Respiratory 1.05 0.961 – 1.14 0.287 566 5926 exclusion phecode
500 Lung disease due to external agents Respiratory 1.03 0.922 – 1.15 0.607 360 3774 exclusion phecode
500.1 Extrinsic allergic alveolitis Respiratory 0.949 0.75 – 1.2 0.662 72 730 exclusion phecode
500.2 Pneumoconiosis Respiratory 1.11 0.963 – 1.28 0.149 210 2186 exclusion phecode
501 Pneumonitis due to inhalation of food or vomitus Respiratory 1.14 1.04 – 1.24 0.00384 570 6095 exclusion phecode
502 Postinflammatory pulmonary fibrosis Respiratory 1.09 1.01 – 1.17 0.0198 803 8485 exclusion phecode
503 Pulmonary congestion and hypostasis Respiratory 1.16 1.04 – 1.28 0.00676 387 4746 exclusion phecode
504 Other alveolar and parietoalveolar pneumonopathy Respiratory 1.16 1.03 – 1.31 0.017 287 3065 exclusion phecode
505 Other pulmonary inflamation or edema Respiratory 1.01 0.763 – 1.34 0.945 57 567 exclusion phecode
506 Empyema and pneumothorax Respiratory 1.03 0.971 – 1.1 0.293 1040 10616 exclusion phecode
507 Pleurisy; pleural effusion Respiratory 1.04 1.01 – 1.07 0.00283 5653 60009 exclusion phecode
508
Pulmonary collapse; interstitial and
Pulmonary collapse; interstitial and compensatory emphysema
 Respiratory 1.05 0.999 – 1.1 0.0556 1778 18719 exclusion phecode
509 Respiratory failure, insufficiency, arrest Respiratory 1.12 1.07 – 1.17 5.33e-07 2189 24263 exclusion phecode
509.1 Respiratory failure Respiratory 1.15 1.09 – 1.2 7.85e-08 1740 19285 exclusion phecode
509.2 Respiratory insufficiency Respiratory 1.15 1.09 – 1.21 4.49e-07 1529 16876 exclusion phecode
509.5 Respiratory arrest Respiratory 0.992 0.828 – 1.19 0.927 127 1341 exclusion phecode
509.8
Dependence on respirator [Ventilator] or
Dependence on respirator [Ventilator] or supplemental oxygen
 Respiratory 1.07 0.953 – 1.2 0.258 316 3606 exclusion phecode
510 Other diseases of lung Respiratory 1.09 1.01 – 1.18 0.0353 678 7063 exclusion phecode
512 Other symptoms of respiratory system Respiratory 1.11 1.08 – 1.14 5.04e-19 7972 85020 exclusion phecode
512.1 Wheezing Respiratory 1.21 1.04 – 1.41 0.0128 191 2053 exclusion phecode
512.2 Painful respiration Respiratory 1.23 1.06 – 1.42 0.00628 199 1962 exclusion phecode
512.7 Shortness of breath Respiratory 1.14 1.1 – 1.17 4.07e-18 5100 55012 exclusion phecode
512.8 Cough Respiratory 1.06 1.02 – 1.11 0.00305 2587 26966 exclusion phecode
512.9 Other dyspnea Respiratory 1.07 0.996 – 1.15 0.063 787 8567 exclusion phecode
513 Respiratory abnormalities Respiratory 1.13 1.03 – 1.23 0.00811 522 5717 exclusion phecode
513.3 Hypoventilation Respiratory 1.14 0.876 – 1.49 0.329 57 776 exclusion phecode
513.4 Hyperventilation Respiratory 1.28 1.12 – 1.45 0.000206 252 2633 exclusion phecode
513.8 Disorders of diaphragm Respiratory 1.11 0.931 – 1.32 0.244 134 1427 exclusion phecode
514 Abnormal findings examination of lungs Respiratory 1.06 1.01 – 1.11 0.0113 2225 22934 exclusion phecode
516 Abnormal sputum Respiratory 1.08 1.03 – 1.13 0.00161 1893 19892 exclusion phecode
516.1 Hemoptysis Respiratory 1.07 1.02 – 1.12 0.00791 1838 19364 exclusion phecode
519
Other diseases of respiratory system, not
Other diseases of respiratory system, not elsewhere classified
 Respiratory 1.08 1.05 – 1.1 5.39e-11 8205 87976 exclusion phecode
519.2 Respiratory complications Respiratory 1.04 0.921 – 1.17 0.529 287 3066 exclusion phecode
519.8 Other diseases of respiratory system, NEC Respiratory 1.08 1.06 – 1.11 1.98e-11 7743 83171 exclusion phecode
519.9
Symptoms involving respiratory system and other
Symptoms involving respiratory system and other chest symptoms
 Respiratory 0.964 0.853 – 1.09 0.555 285 2872 exclusion phecode
520 Disorders of tooth development Digestive 0.995 0.949 – 1.04 0.825 1937 19484 exclusion phecode
520.1 Hereditary disturbances in tooth structure Digestive 0.974 0.731 – 1.3 0.856 50 512 exclusion phecode
520.2 Disturbances in tooth eruption Digestive 0.999 0.956 – 1.04 0.953 2249 22566 exclusion phecode
521 Diseases of hard tissues of teeth Digestive 1.09 1.04 – 1.13 3.8e-05 2715 28722 exclusion phecode
521.1 Dental caries Digestive 1.09 1.05 – 1.13 1.87e-05 2724 28828 exclusion phecode
522 Diseases of pulp and periapical tissues Digestive 1.03 0.98 – 1.08 0.242 1665 16910 exclusion phecode
522.5 Periapical abscess Digestive 1.05 0.983 – 1.11 0.156 1089 11171 exclusion phecode
523 Gingival and periodontal diseases Digestive 1.01 0.958 – 1.06 0.728 1574 16027 exclusion phecode
523.1 Gingivitis Digestive 1.03 0.84 – 1.25 0.799 109 1073 exclusion phecode
523.3 Periodontitis (acute or chronic) Digestive 1 0.942 – 1.07 0.964 1110 11138 exclusion phecode
523.31 Acute periodontitis Digestive 1.01 0.931 – 1.1 0.806 636 6402 exclusion phecode
523.32 Chronic periodontitis Digestive 1.01 0.923 – 1.1 0.857 534 5310 exclusion phecode
524 Dentofacial anomalies, including malocclusion Digestive 1.03 0.914 – 1.15 0.672 319 3167 exclusion phecode
524.3 Anomalies of tooth position/malocclusion Digestive 0.999 0.886 – 1.13 0.982 294 2909 exclusion phecode
525
Other diseases of the teeth and supporting
Other diseases of the teeth and supporting structures
 Digestive 1.09 1.04 – 1.13 9.12e-05 2453 25252 exclusion phecode
525.2 Atrophy of edentulous alveolar ridge Digestive 0.851 0.665 – 1.09 0.2 68 675 exclusion phecode
526 Diseases of the jaws Digestive 1.06 0.992 – 1.14 0.0838 877 8840 exclusion phecode
526.1 Cysts of the jaws Digestive 0.997 0.886 – 1.12 0.965 306 3125 exclusion phecode
526.3 Anomalies of jaw size/symmetry Digestive 0.978 0.758 – 1.26 0.865 59 588 exclusion phecode
526.4 Temporomandibular joint disorders Digestive 1.09 0.96 – 1.24 0.18 232 2317 exclusion phecode
526.41 Temporomandibular joint disorder, unspecified Digestive 1.11 0.976 – 1.27 0.109 225 2252 exclusion phecode
526.5 Inflammatory conditions of jaw Digestive 0.942 0.764 – 1.16 0.572 101 1048 exclusion phecode
526.9 Jaw disease NOS Digestive 1.17 1.02 – 1.34 0.0289 221 2187 exclusion phecode
527 Diseases of the salivary glands Digestive 1.12 1.03 – 1.21 0.00768 631 6570 exclusion phecode
527.1 Hypertrophy of salivary gland Digestive 1.16 0.919 – 1.46 0.216 77 790 exclusion phecode
527.2 Sialoadenitis Digestive 1.1 0.987 – 1.24 0.0823 331 3475 exclusion phecode
527.7 Disturbance of salivary secretion Digestive 0.986 0.755 – 1.29 0.919 58 585 exclusion phecode
527.8 Other specified diseases of the salivary glands Digestive 1.03 0.845 – 1.26 0.768 114 1130 exclusion phecode
528
Diseases of the oral soft tissues, excluding
Diseases of the oral soft tissues, excluding lesions specific for gingiva and tongue
 Digestive 1.05 1.02 – 1.09 0.00362 3592 36647 exclusion phecode
528.1 Stomatitis and mucositis Digestive 1.01 0.912 – 1.11 0.903 426 4417 exclusion phecode
528.11 Stomatitis and mucositis (ulcerative) Digestive 1.01 0.911 – 1.13 0.788 354 3675 exclusion phecode
528.12 Oral aphthae Digestive 1.02 0.811 – 1.28 0.869 76 795 exclusion phecode
528.3 Cellulitis and abscess of oral soft tissues Digestive 1.06 0.901 – 1.24 0.502 161 1693 exclusion phecode
528.4 Cysts of oral soft tissues Digestive 1.06 0.878 – 1.28 0.54 119 1152 exclusion phecode
528.41 Cyst of the salivary gland Digestive 1.07 0.866 – 1.33 0.513 92 889 exclusion phecode
528.5 Diseases of lips Digestive 1.01 0.931 – 1.09 0.828 648 6442 exclusion phecode
528.6 Leukoplakia of oral mucosa Digestive 1.2 1.06 – 1.36 0.00326 282 2915 exclusion phecode
528.7 Sialolithiasis Digestive 1.04 0.918 – 1.17 0.551 288 2949 exclusion phecode
529 Diseases and other conditions of the tongue Digestive 1.03 0.964 – 1.09 0.42 1127 11615 exclusion phecode
529.1 Glossitis Digestive 1.19 1.05 – 1.35 0.0073 269 2816 exclusion phecode
530 Diseases of esophagus Digestive 1.08 1.07 – 1.1 2.43e-41 30729 264360 exclusion phecode
530.1 Esophagitis, GERD and related diseases Digestive 1.09 1.07 – 1.1 1.11e-40 28746 257848 exclusion phecode
530.11 GERD Digestive 1.09 1.07 – 1.11 1.63e-32 20933 213547 exclusion phecode
530.12 Ulcer of esophagus Digestive 1.08 1.05 – 1.12 2.01e-07 4732 48651 exclusion phecode
530.14 Reflux esophagitis Digestive 1.09 1.06 – 1.11 1.14e-14 9652 98531 exclusion phecode
530.2 Esophageal bleeding (varices/hemorrhage) Digestive 1.1 1.04 – 1.16 0.000758 1449 15782 exclusion phecode
530.3 Stricture and stenosis of esophagus Digestive 1.03 0.977 – 1.08 0.298 1716 17450 exclusion phecode
530.5 Disorders of esophageal motility Digestive 1.09 0.998 – 1.18 0.0557 591 6027 exclusion phecode
530.6 Diverticulum of esophagus, acquired Digestive 1.11 0.93 – 1.32 0.25 141 1432 exclusion phecode
530.7 Gastroesophageal laceration-hemorrhage syndrome Digestive 1.11 0.99 – 1.26 0.0727 307 3240 exclusion phecode
530.9 Heartburn Digestive 1.07 1.02 – 1.12 0.00446 1963 19749 exclusion phecode
531 Peptic ulcer (excl. esophageal) Digestive 1.11 1.09 – 1.14 1.5e-16 6334 66470 exclusion phecode
531.1 Hemorrhage from gastrointestinal ulcer Digestive 1.1 1.01 – 1.2 0.0271 576 5886 exclusion phecode
531.2 Gastric ulcer Digestive 1.09 1.06 – 1.13 2.63e-07 3616 38404 exclusion phecode
531.3 Duodenal ulcer Digestive 1.17 1.12 – 1.21 2.51e-14 2710 27967 exclusion phecode
531.4 Peptic ulcer, site unspecified Digestive 1.18 1.07 – 1.31 0.00145 378 3960 exclusion phecode
532 Dysphagia Digestive 1.06 1.03 – 1.09 2.68e-05 5929 60706 exclusion phecode
535 Gastritis and duodenitis Digestive 1.09 1.08 – 1.1 1.2e-38 25512 247401 exclusion phecode
535.1 Acute gastritis Digestive 1.18 1.11 – 1.26 2.17e-07 1043 11095 exclusion phecode
535.2 Atrophic gastritis Digestive 1.13 1.01 – 1.27 0.0304 332 3460 exclusion phecode
535.6 Duodenitis Digestive 1.09 1.07 – 1.12 9.32e-13 6866 71419 exclusion phecode
535.8 Other specified gastritis Digestive 1.09 1.06 – 1.12 3.13e-12 7303 76187 exclusion phecode
535.9 Gastritis and duodenitis, NOS Digestive 1.23 1.01 – 1.51 0.0399 111 1112 exclusion phecode
536.8
Dyspepsia and other specified disorders of
Dyspepsia and other specified disorders of function of stomach
 Digestive 0.974 0.856 – 1.11 0.697 237 2437 exclusion phecode
537 Other disorders of stomach and duodenum Digestive 1.08 1.04 – 1.12 6.63e-05 3017 31937 exclusion phecode
540 Appendiceal conditions Digestive 1.05 1.01 – 1.09 0.0117 2946 29333 exclusion phecode
540.1 Appendicitis Digestive 1.05 1.01 – 1.09 0.0265 2768 27499 exclusion phecode
540.11 Acute appendicitis Digestive 1.03 0.986 – 1.07 0.194 2486 24685 exclusion phecode
550 Abdominal hernia Digestive 1.05 1.04 – 1.06 1.04e-18 42036 267890 exclusion phecode
550.1 Inguinal hernia Digestive 0.98 0.964 – 0.997 0.0222 15043 114143 exclusion phecode
550.2 Diaphragmatic hernia Digestive 1.08 1.07 – 1.1 2.56e-31 24303 225693 exclusion phecode
550.3 Femoral hernia Digestive 0.893 0.823 – 0.969 0.00656 643 6178 exclusion phecode
550.4 Umbilical hernia Digestive 1.06 1.02 – 1.1 0.00244 3231 34608 exclusion phecode
550.5 Ventral hernia Digestive 1.1 1.06 – 1.15 1.93e-07 3094 32276 exclusion phecode
555
Inflammatory bowel disease and other
Inflammatory bowel disease and other gastroenteritis and colitis
 Digestive 1.04 1.01 – 1.08 0.0091 4110 42198 exclusion phecode
555.1 Regional enteritis Digestive 1.09 1.04 – 1.15 0.000761 1615 16508 exclusion phecode
555.2 Ulcerative colitis Digestive 1.03 0.99 – 1.07 0.143 2925 30119 exclusion phecode
555.21 Ulcerative colitis (chronic) Digestive 0.958 0.874 – 1.05 0.352 500 5102 exclusion phecode
556 Ulceration of the lower GI tract Digestive 1.13 1.06 – 1.2 0.000357 980 10066 exclusion phecode
556.1 Ulceration of intestine Digestive 1.14 1.05 – 1.24 0.00163 624 6385 exclusion phecode
557 Intestinal malabsorption (non-celiac) Digestive 1.03 0.905 – 1.16 0.68 269 2867 exclusion phecode
557.1 Celiac disease Digestive 1.17 1.11 – 1.23 4.58e-10 1728 17479 exclusion phecode
558 Noninfectious gastroenteritis Digestive 1.08 1.06 – 1.09 2.15e-16 13933 147608 exclusion phecode
559 Ileostomy status Digestive 1.07 1.01 – 1.12 0.0193 1505 15646 exclusion phecode
560 Intestinal obstruction without mention of hernia Digestive 1.04 1 – 1.07 0.0455 3625 37175 exclusion phecode
560.1 Paralytic ileus Digestive 1.06 0.969 – 1.17 0.193 475 4886 exclusion phecode
560.2 Impaction of intestine Digestive 0.973 0.854 – 1.11 0.68 245 2535 exclusion phecode
560.3 Peritoneal or intestinal adhesions Digestive 1.05 0.972 – 1.13 0.231 773 7898 exclusion phecode
560.4 Other intestinal obstruction Digestive 1.03 0.997 – 1.07 0.0687 3106 31745 exclusion phecode
561 Symptoms involving digestive system Digestive 1.05 1.03 – 1.07 7.44e-08 14628 150168 exclusion phecode
561.1 Diarrhea Digestive 1.07 0.966 – 1.18 0.2 442 4407 exclusion phecode
561.2 Flatulence Digestive 1.06 1 – 1.11 0.0415 1577 16031 exclusion phecode
562 Diverticulosis and diverticulitis Digestive 1.07 1.05 – 1.08 3.82e-21 24336 200327 exclusion phecode
562.1 Diverticulosis Digestive 1.07 1.05 – 1.08 4.84e-21 24304 200278 exclusion phecode
563 Constipation Digestive 1.07 1.04 – 1.09 5.32e-09 9388 97782 exclusion phecode
564 Functional digestive disorders Digestive 1.09 1.08 – 1.11 2.14e-32 19892 199204 exclusion phecode
564.1 Irritable Bowel Syndrome Digestive 1.1 1.07 – 1.13 1.84e-10 5125 52788 exclusion phecode
564.8
Abnormal findings on exam of gastrointestinal
Abnormal findings on exam of gastrointestinal tract/ abdominal area
 Digestive 1.09 1.04 – 1.15 0.00116 1506 15594 exclusion phecode
564.9 Personal history of diseases of digestive system Digestive 1.1 1.08 – 1.12 9.38e-26 13876 143160 exclusion phecode
565 Anal and rectal conditions Digestive 1.06 1.04 – 1.07 1.43e-09 13575 138890 exclusion phecode
565.1 Anal and rectal polyp Digestive 1.06 1.03 – 1.09 9.41e-06 6731 68946 exclusion phecode
567 Peritonitis and retroperitoneal infections Digestive 1.04 0.971 – 1.12 0.255 807 8736 exclusion phecode
568 Other disorders of peritoneum Digestive 1.1 1.06 – 1.15 1.79e-07 3010 30910 exclusion phecode
568.1
Peritoneal adhesions (postoperative)
Peritoneal adhesions (postoperative) (postinfection)
 Digestive 1.11 1.07 – 1.16 5.89e-08 2863 29370 exclusion phecode
569 Other disorders of intestine Digestive 1.05 1.02 – 1.09 0.00287 3781 39469 exclusion phecode
569.1 Toxic gastroenteritis and colitis Digestive 1.11 0.927 – 1.32 0.263 130 1387 exclusion phecode
569.2 Gastrointestinal complications Digestive 0.981 0.892 – 1.08 0.692 452 4552 exclusion phecode
571 Chronic liver disease and cirrhosis Digestive 1.22 1.17 – 1.27 3.6e-20 2298 27875 exclusion phecode
571.5 Other chronic nonalcoholic liver disease Digestive 1.33 1.26 – 1.41 5.39e-23 1276 15957 exclusion phecode
571.51 Cirrhosis of liver without mention of alcohol Digestive 1.17 0.946 – 1.46 0.146 85 1064 exclusion phecode
571.6 Primary biliary cirrhosis Digestive 1.05 0.918 – 1.2 0.476 235 2450 exclusion phecode
571.8
Liver abscess and sequelae of chronic liver
Liver abscess and sequelae of chronic liver disease
 Digestive 1.1 1.02 – 1.19 0.0108 752 9194 exclusion phecode
571.81 Portal hypertension Digestive 1.14 1.03 – 1.27 0.0115 380 4962 exclusion phecode
572 Ascites (non malignant) Digestive 1.1 1.04 – 1.16 0.000975 1327 14521 exclusion phecode
573 Other disorders of liver Digestive 1.07 1.01 – 1.13 0.0226 1341 14109 exclusion phecode
573.2 Liver replaced by transplant Digestive 1.25 0.991 – 1.58 0.0596 72 901 exclusion phecode
573.3 Hepatomegaly Digestive 1.08 0.943 – 1.23 0.274 244 2785 exclusion phecode
573.5 Jaundice (not of newborn) Digestive 1.06 0.987 – 1.14 0.106 798 8392 exclusion phecode
573.7 Abnormal results of function study of liver Digestive 1.12 1.08 – 1.16 7.27e-09 3027 32618 exclusion phecode
573.9 Abnormal serum enzyme levels Digestive 0.999 0.857 – 1.17 0.99 182 1938 exclusion phecode
574 Cholelithiasis and cholecystitis Digestive 1.15 1.13 – 1.17 2.95e-54 14237 148220 exclusion phecode
574.1 Cholelithiasis Digestive 1.14 1.12 – 1.16 1.23e-45 12362 128746 exclusion phecode
574.11 Cholelithiasis with acute cholecystitis Digestive 1.2 1.13 – 1.27 2.93e-10 1362 14233 exclusion phecode
574.12 Cholelithiasis with other cholecystitis Digestive 1.15 1.12 – 1.18 7.84e-21 4994 51608 exclusion phecode
574.2 Calculus of bile duct Digestive 1.14 1.09 – 1.18 2.43e-09 2397 24744 exclusion phecode
574.3 Cholecystitis without cholelithiasis Digestive 1.17 1.12 – 1.22 2.29e-13 2453 26038 exclusion phecode
575 Other biliary tract disease Digestive 1.13 1.09 – 1.17 4.33e-12 3517 36487 exclusion phecode
575.1 Cholangitis Digestive 1.16 1.05 – 1.28 0.0029 439 4584 exclusion phecode
575.2 Obstruction of bile duct Digestive 1.11 1.02 – 1.2 0.00989 687 7223 exclusion phecode
575.6 Cholesterolosis of gallbladder Digestive 1.32 1.19 – 1.45 5.04e-08 429 4368 exclusion phecode
575.7 Other disorders of gallbladder Digestive 1.13 1.07 – 1.2 2.28e-05 1296 13362 exclusion phecode
575.8 Other disorders of biliary tract Digestive 1.08 1.01 – 1.15 0.028 937 9770 exclusion phecode
575.9
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of biliary tract
 Digestive 1.12 0.993 – 1.25 0.0657 311 3264 exclusion phecode
577 Diseases of pancreas Digestive 1.14 1.09 – 1.19 1.32e-09 2318 25039 exclusion phecode
577.1 Acute pancreatitis Digestive 1.16 1.1 – 1.21 4.3e-09 1749 18760 exclusion phecode
577.2 Chronic pancreatitis Digestive 1.3 1.17 – 1.44 1.07e-06 402 4821 exclusion phecode
577.3 Cyst and pseudocyst of pancreas Digestive 1.16 1.04 – 1.3 0.0101 306 3419 exclusion phecode
578 Gastrointestinal hemorrhage Digestive 1.05 1.03 – 1.07 1.2e-10 19004 194935 exclusion phecode
578.1 Hematemesis Digestive 1.09 1.04 – 1.15 0.000494 1710 18403 exclusion phecode
578.2 Blood in stool Digestive 1.07 1.03 – 1.12 0.00135 2348 24635 exclusion phecode
578.8 Hemorrhage of rectum and anus Digestive 1.05 1.03 – 1.07 1.62e-06 12141 123882 exclusion phecode
578.9 Hemorrhage of gastrointestinal tract Digestive 1.04 1.01 – 1.07 0.0148 4852 49810 exclusion phecode
579 Other symptoms involving abdomen and pelvis Digestive 1.02 0.967 – 1.08 0.429 1360 14667 exclusion phecode
579.2 Splenomegaly Digestive 0.979 0.873 – 1.1 0.712 332 3963 exclusion phecode
579.8 Nonspecific abnormal findings in stool contents Digestive 1.03 0.975 – 1.08 0.3 1505 15642 exclusion phecode
580 Nephritis; nephrosis; renal sclerosis Genitourinary 1.1 1.03 – 1.17 0.00376 1062 14380 exclusion phecode
580.1 Glomerulonephritis Genitourinary 1.11 1.03 – 1.2 0.00387 790 9865 exclusion phecode
580.11 Proliferative glomerulonephritis Genitourinary 1.12 0.868 – 1.44 0.388 65 695 exclusion phecode
580.12 Non-proliferative glomerulonephritis Genitourinary 1.18 0.979 – 1.42 0.0822 120 1288 exclusion phecode
580.14 Chronic glomerulonephritis, NOS Genitourinary 1.1 1.01 – 1.19 0.0279 634 8183 exclusion phecode
580.2
Nephrotic syndrome without mention of
Nephrotic syndrome without mention of glomerulonephritis
 Genitourinary 1.09 0.958 – 1.24 0.189 227 4397 exclusion phecode
580.3
Nephritis and nephropathy without mention of
Nephritis and nephropathy without mention of glomerulonephritis
 Genitourinary 1.14 0.991 – 1.32 0.0666 204 2328 exclusion phecode
580.32
Nephritis and nephropathy with pathological
Nephritis and nephropathy with pathological lesion
 Genitourinary 1.12 0.971 – 1.29 0.119 207 2397 exclusion phecode
585 Renal failure Genitourinary 1.1 1.07 – 1.13 1.19e-11 5425 64995 exclusion phecode
585.1 Acute renal failure Genitourinary 1.09 1.05 – 1.12 3.49e-06 3464 42142 exclusion phecode
585.2 Renal failure NOS Genitourinary 1.06 0.995 – 1.12 0.0719 1172 13634 exclusion phecode
585.3 Chronic renal failure [CKD] Genitourinary 1.17 1.12 – 1.23 2.1e-11 1923 24661 exclusion phecode
585.31 Renal dialysis Genitourinary 1.09 0.982 – 1.21 0.106 380 4640 exclusion phecode
586 Other disorders of the kidney and ureters Genitourinary 1.06 1.02 – 1.1 0.00376 2972 31547 exclusion phecode
586.1 Anatomical abnormatilies of kidney and ureters Genitourinary 1.06 0.913 – 1.23 0.437 185 1974 exclusion phecode
586.11 Small kidney Genitourinary 1.12 0.951 – 1.31 0.179 157 1701 exclusion phecode
586.2 Cyst of kidney, acquired Genitourinary 1.05 0.986 – 1.11 0.131 1135 11756 exclusion phecode
586.3 Vascular disorders of kidney/hypertrophy Genitourinary 1.04 0.809 – 1.33 0.783 70 747 exclusion phecode
586.4 Stricture/obstruction of ureter Genitourinary 1.1 1.03 – 1.18 0.00642 818 8584 exclusion phecode
587 Kidney replaced by transpant Genitourinary 1.07 0.951 – 1.2 0.263 307 3498 exclusion phecode
588 Disorders resulting from impaired renal function Genitourinary 1.09 0.869 – 1.38 0.447 78 923 exclusion phecode
589 Abnormal results of function study of kidney Genitourinary 0.91 0.737 – 1.12 0.38 94 1096 exclusion phecode
590 Pyelonephritis Genitourinary 1.14 1.08 – 1.21 9.4e-06 1180 12664 exclusion phecode
591 Urinary tract infection Genitourinary 1.05 1.03 – 1.07 8.45e-07 10956 116943 exclusion phecode
592 Cystitis and urethritis Genitourinary 1.06 1.02 – 1.11 0.00242 2703 28064 exclusion phecode
592.1 Cystitis Genitourinary 1.06 1.02 – 1.11 0.00267 2647 27483 exclusion phecode
592.11 Acute cystitis Genitourinary 0.84 0.7 – 1.01 0.06 127 1288 exclusion phecode
592.12 Chronic cystitis Genitourinary 1.09 1.02 – 1.17 0.0146 809 8385 exclusion phecode
592.13 Chronic interstitial cystitis Genitourinary 1.02 0.89 – 1.16 0.804 234 2359 exclusion phecode
592.2 Urethritis and urethral syndrome Genitourinary 1.07 0.909 – 1.27 0.405 152 1577 exclusion phecode
593 Hematuria Genitourinary 1.05 1.03 – 1.07 3.66e-09 14660 150490 exclusion phecode
594 Urinary calculus Genitourinary 1.11 1.08 – 1.14 2.18e-13 5637 59787 exclusion phecode
594.1 Calculus of kidney Genitourinary 1.09 1.05 – 1.14 7.36e-06 2770 29764 exclusion phecode
594.2 Calculus of lower urinary tract Genitourinary 1.14 1.05 – 1.23 0.00146 676 7198 exclusion phecode
594.3 Calculus of ureter Genitourinary 1.11 1.06 – 1.16 8.5e-06 2104 22472 exclusion phecode
594.8 Renal colic Genitourinary 1.11 1.06 – 1.17 9.64e-06 1830 19298 exclusion phecode
595 Hydronephrosis Genitourinary 1.11 1.06 – 1.17 1.96e-05 1708 18144 exclusion phecode
596 Other disorders of bladder Genitourinary 1.05 1.03 – 1.07 1.39e-05 8894 91056 exclusion phecode
596.1 Bladder neck obstruction Genitourinary 1.04 0.992 – 1.09 0.105 1785 18071 exclusion phecode
596.5 Functional disorders of bladder Genitourinary 1.03 0.977 – 1.09 0.27 1505 15631 exclusion phecode
597 Other disorders of urethra and urinary tract Genitourinary 1.08 1.04 – 1.11 2.59e-05 3558 36701 exclusion phecode
597.1 Urethral stricture (not specified as infectious) Genitourinary 1.08 1.04 – 1.12 3.81e-05 3002 31026 exclusion phecode
597.2 Urinary complications NEC Genitourinary 1.18 0.926 – 1.51 0.181 67 728 exclusion phecode
598 Abnormal findings on examination of urine Genitourinary 1.02 0.988 – 1.06 0.198 3201 32890 exclusion phecode
598.9
Other nonspecific findings on examination of
Other nonspecific findings on examination of urine
 Genitourinary 0.99 0.875 – 1.12 0.879 270 2848 exclusion phecode
599 Other symptoms/disorders or the urinary system Genitourinary 1.08 1.06 – 1.09 1.57e-19 16879 174093 exclusion phecode
599.1 Urinary obstruction Genitourinary 0.926 0.781 – 1.1 0.373 141 1543 exclusion phecode
599.2 Retention of urine Genitourinary 1.08 1.05 – 1.11 1.32e-08 6033 62088 exclusion phecode
599.3 Dysuria Genitourinary 1.04 0.974 – 1.1 0.262 1082 11281 exclusion phecode
599.4 Urinary incontinence Genitourinary 1.1 1.07 – 1.12 3.4e-15 8118 83676 exclusion phecode
599.5 Frequency of urination and polyuria Genitourinary 1.02 0.991 – 1.06 0.155 3641 37653 exclusion phecode
599.6 Oliguria and anuria Genitourinary 1.13 0.91 – 1.41 0.264 84 989 exclusion phecode
599.8 Other symptoms involving urinary system Genitourinary 1.26 0.963 – 1.65 0.0921 60 577 exclusion phecode
599.9 Other abnormality of urination Genitourinary 1.05 0.999 – 1.1 0.0533 1726 17873 exclusion phecode
600 Hyperplasia of prostate Genitourinary 1.04 1.02 – 1.06 0.000128 9996 80373 exclusion phecode
601 Inflammatory diseases of prostate Genitourinary 1.06 1.01 – 1.11 0.0227 1876 19115 exclusion phecode
601.1 Prostatitis Genitourinary 1.06 1 – 1.12 0.0412 1456 14346 exclusion phecode
601.11 Acute prostatitis Genitourinary 1.04 0.906 – 1.2 0.565 214 2159 exclusion phecode
601.12 Chronic prostatitis Genitourinary 1 0.936 – 1.08 0.909 838 8250 exclusion phecode
601.3 Orchitis and epididymitis Genitourinary 0.861 0.66 – 1.12 0.269 55 543 exclusion phecode
601.4 Balanoposthitis Genitourinary 0.989 0.866 – 1.13 0.865 227 2628 exclusion phecode
601.8
Other inflammatory disorders of male genital
Other inflammatory disorders of male genital organs
 Genitourinary 1.13 0.996 – 1.28 0.0568 259 2786 exclusion phecode
602 Other disorders of prostate Genitourinary 1.06 0.996 – 1.12 0.0663 1216 12179 exclusion phecode
603 Other disorders of testis Genitourinary 1.11 1.06 – 1.16 2.64e-05 1921 19960 exclusion phecode
603.1 Hydrocele Genitourinary 1.12 1.06 – 1.19 0.000181 1197 12347 exclusion phecode
604 Disorders of penis Genitourinary 1.07 1.03 – 1.11 0.000811 2786 30489 exclusion phecode
604.1 Redundant prepuce and phimosis/BXO Genitourinary 1.06 1.01 – 1.11 0.00835 2287 25254 exclusion phecode
605 Erectile dysfunction [ED] Genitourinary 1.07 0.934 – 1.23 0.327 222 2516 exclusion phecode
608 Other disorders of male genital organs Genitourinary 1.02 0.98 – 1.06 0.324 2616 26196 exclusion phecode
609 Male infertility and abnormal spermatozoa Genitourinary 0.945 0.812 – 1.1 0.465 190 1955 exclusion phecode
609.1 Infertility, male Genitourinary 0.866 0.666 – 1.13 0.283 57 604 exclusion phecode
609.2 Abnormal spermatozoa Genitourinary 0.99 0.838 – 1.17 0.908 149 1527 exclusion phecode
610 Benign mammary dysplasias Genitourinary 0.99 0.949 – 1.03 0.636 2382 23939 exclusion phecode
610.1 Cystic mastopathy Genitourinary 0.891 0.832 – 0.955 0.00117 886 8911 exclusion phecode
610.2 Fibroadenosis of breast Genitourinary 1.02 0.911 – 1.15 0.683 293 2939 exclusion phecode
610.3 Fibrosclerosis of breast Genitourinary 1.07 0.942 – 1.2 0.313 292 2908 exclusion phecode
610.4 Benign neoplasm of breast Genitourinary 0.995 0.94 – 1.05 0.856 1341 13391 exclusion phecode
610.8 Other specified benign mammary dysplasias Genitourinary 1.03 0.948 – 1.12 0.499 648 6695 exclusion phecode
611 Abnormal findings on mammogram or breast exam Genitourinary 1 0.95 – 1.06 0.946 1509 15151 exclusion phecode
611.1 Abnormal mammogram Genitourinary 1.07 0.821 – 1.4 0.603 56 543 exclusion phecode
611.3 Lump or mass in breast Genitourinary 1 0.952 – 1.06 0.861 1458 14671 exclusion phecode
612
Breast conditions, congenital or relating to
Breast conditions, congenital or relating to hormones
 Genitourinary 1.09 1.02 – 1.17 0.0152 834 8530 exclusion phecode
612.2 Hypertrophy of breast (Gynecomastia) Genitourinary 1.07 0.993 – 1.15 0.0771 792 8135 exclusion phecode
612.3 Congenital anomalies of breast Genitourinary 1.11 0.883 – 1.4 0.362 72 702 exclusion phecode
613 Other nonmalignant breast conditions Genitourinary 1.06 1.01 – 1.12 0.023 1562 15868 exclusion phecode
613.1 Inflammatory disease of breast Genitourinary 1.12 1.03 – 1.21 0.00547 681 6902 exclusion phecode
613.5 Mastodynia Genitourinary 1.05 0.819 – 1.34 0.72 71 740 exclusion phecode
613.7 Other signs and symptoms in breast Genitourinary 0.972 0.898 – 1.05 0.48 674 6734 exclusion phecode
613.8 Other specified disorders of breast Genitourinary 1.04 0.92 – 1.17 0.565 308 3153 exclusion phecode
613.9 Breast disorder NOS Genitourinary 0.983 0.85 – 1.14 0.817 195 1993 exclusion phecode
614 Inflammatory diseases of female pelvic organs Genitourinary 1.07 1.05 – 1.11 3.91e-07 5440 55217 exclusion phecode
614.1
Pelvic peritoneal adhesions, female
Pelvic peritoneal adhesions, female (postoperative) (postinfection)
 Genitourinary 1.11 1.06 – 1.16 1.39e-06 2415 24562 exclusion phecode
614.3 Pelvic inflammatory disease (PID) Genitourinary 1.14 1.06 – 1.23 0.000508 786 8054 exclusion phecode
614.31 Acute inflammatory pelvic disease Genitourinary 1.39 1.05 – 1.82 0.0201 58 589 exclusion phecode
614.32 Chronic inflammatory pelvic disease Genitourinary 1.18 1.06 – 1.3 0.00193 401 4085 exclusion phecode
614.33 Pelvic inflammatory disease, NOS Genitourinary 1.05 0.941 – 1.18 0.364 331 3406 exclusion phecode
614.4 Inflammatory diseases of uterus, except cervix Genitourinary 1.06 0.934 – 1.2 0.37 260 2681 exclusion phecode
614.5
Inflammatory disease of cervix, vagina, and
Inflammatory disease of cervix, vagina, and vulva
 Genitourinary 1.05 1 – 1.09 0.0333 2489 25106 exclusion phecode
614.51 Cervicitis and endocervicitis Genitourinary 1.01 0.956 – 1.07 0.665 1273 12705 exclusion phecode
614.52 Vaginitis and vulvovaginitis Genitourinary 1.1 0.993 – 1.22 0.0686 400 4104 exclusion phecode
614.53 Cyst or abscess of Bartholin's gland Genitourinary 1.01 0.937 – 1.09 0.76 738 7335 exclusion phecode
614.54 Abscess or ulceration of vulva Genitourinary 1.17 1.03 – 1.34 0.0192 239 2637 exclusion phecode
615 Endometriosis Genitourinary 1.09 1.05 – 1.13 2.9e-07 3889 39090 exclusion phecode
617
Disorders secondary to childbirth, surgery
Disorders secondary to childbirth, surgery, trauma
 Genitourinary 1.06 0.939 – 1.2 0.333 282 2913 exclusion phecode
618 Genital prolapse Genitourinary 1.07 1.05 – 1.09 1.11e-10 11118 112036 exclusion phecode
618.1 Prolapse of vaginal walls Genitourinary 1.08 1.05 – 1.11 1.47e-09 7003 70837 exclusion phecode
618.2 Uterine/Uterovaginal prolapse Genitourinary 1.05 1.02 – 1.08 0.000791 5155 51655 exclusion phecode
618.5 Prolapse of vaginal vault after hysterectomy Genitourinary 1.12 1.02 – 1.23 0.0174 486 4904 exclusion phecode
618.6 Vaginal enterocele, congenital or acquired Genitourinary 1.1 1.01 – 1.19 0.0253 644 6499 exclusion phecode
619 Noninflammatory female genital disorders Genitourinary 1.04 1.02 – 1.07 0.000219 8363 84184 exclusion phecode
619.1
Noninflammatory disorders of ovary, fallopian
Noninflammatory disorders of ovary, fallopian tube, and broad ligament
 Genitourinary 1.04 0.961 – 1.12 0.334 693 7033 exclusion phecode
619.2 Disorders of uterus, NEC Genitourinary 1.05 1.01 – 1.09 0.00584 3193 32009 exclusion phecode
619.3 Noninflammatory disorders of cervix Genitourinary 1.05 1.01 – 1.09 0.0177 2749 27642 exclusion phecode
619.4 Noninflammatory disorders of vagina Genitourinary 0.969 0.922 – 1.02 0.227 1677 17029 exclusion phecode
619.5 Noninflammatory disorders of vulva and perineum Genitourinary 1.01 0.956 – 1.07 0.678 1300 13027 exclusion phecode
620 Dysplasia of female genital organs Genitourinary 1.04 0.82 – 1.31 0.754 69 696 exclusion phecode
621 Endometrial hyperplasia Genitourinary 1.07 1 – 1.14 0.048 1039 10848 exclusion phecode
622 Polyp of female genital organs Genitourinary 1.03 1.01 – 1.05 0.0143 9968 100916 exclusion phecode
622.1 Polyp of corpus uteri Genitourinary 1.03 1 – 1.05 0.0194 7440 75629 exclusion phecode
622.2 Mucous polyp of cervix Genitourinary 1 0.968 – 1.04 0.846 3310 33101 exclusion phecode
623 Hypertrophy of female genital organs Genitourinary 1.08 1.02 – 1.14 0.0137 1206 12258 exclusion phecode
624 Symptoms involving female genital tract Genitourinary 1.06 0.986 – 1.14 0.115 763 7635 exclusion phecode
624.1 Dystrophy of female genital tract Genitourinary 1.08 0.942 – 1.25 0.263 223 2263 exclusion phecode
624.2 Atrophy of female genital tract Genitourinary 1.1 0.998 – 1.22 0.0557 424 4232 exclusion phecode
624.9 stress incontinence, female Genitourinary 1.12 1.09 – 1.15 1.28e-15 5523 56453 exclusion phecode
625
Pain and other symptoms associated with female
Pain and other symptoms associated with female genital organs
 Genitourinary 1.04 1 – 1.08 0.042 2785 27865 exclusion phecode
625.1 Dyspareunia Genitourinary 1.02 0.961 – 1.09 0.498 1145 11517 exclusion phecode
626
Disorders of menstruation and other abnormal
Disorders of menstruation and other abnormal bleeding from female genital tract
 Genitourinary 1.08 1.06 – 1.1 7.17e-18 15528 111487 exclusion phecode
626.1 Irregular menstrual cycle/bleeding Genitourinary 1.08 1.07 – 1.1 5.77e-19 13545 106593 exclusion phecode
626.11 Absent or infrequent menstruation Genitourinary 0.927 0.757 – 1.13 0.46 104 1065 exclusion phecode
626.12 Excessive or frequent menstruation Genitourinary 1.11 1.08 – 1.13 3.66e-20 9300 88996 exclusion phecode
626.13 Irregular menstrual cycle Genitourinary 1.03 0.983 – 1.08 0.206 1893 19168 exclusion phecode
626.14 Irregular menstrual bleeding Genitourinary 1.07 1.04 – 1.11 3.73e-05 3672 36941 exclusion phecode
626.2 Dysmenorrhea Genitourinary 1.12 1.06 – 1.17 1.49e-05 1699 17257 exclusion phecode
626.4 Premenstrual tension syndromes Genitourinary 1.1 0.936 – 1.3 0.24 156 1546 exclusion phecode
626.8 Infertility, female Genitourinary 0.975 0.921 – 1.03 0.391 1330 13255 exclusion phecode
627 Menopausal and postmenopausal disorders Genitourinary 1.04 1.02 – 1.06 0.000314 9793 99738 exclusion phecode
627.1 Postmenopausal bleeding Genitourinary 1.04 1.02 – 1.06 0.00105 8516 86721 exclusion phecode
627.2 Symptomatic menopause Genitourinary 1.13 0.971 – 1.32 0.112 176 1772 exclusion phecode
627.3 Postmenopausal atrophic vaginitis Genitourinary 1.04 0.973 – 1.1 0.269 1065 10660 exclusion phecode
627.4 Premenopausal menorrhagia Genitourinary 1.03 0.915 – 1.16 0.615 289 2989 exclusion phecode
628 Ovarian cyst Genitourinary 1.1 1.06 – 1.13 3.07e-09 4542 45955 exclusion phecode
634 Miscarriage; stillbirth Pregnancy Complications 0.953 0.925 – 0.982 0.00156 5105 35607 exclusion phecode
634.1 Missed abortion/Hydatidiform mole Pregnancy Complications 0.919 0.864 – 0.977 0.00682 1111 11073 exclusion phecode
634.3 Ectopic pregnancy Pregnancy Complications 1.09 0.972 – 1.22 0.142 324 3241 exclusion phecode
635
Hemorrhage during pregnancy; childbirth and
Hemorrhage during pregnancy; childbirth and postpartum
 Pregnancy Complications 0.942 0.899 – 0.988 0.0134 1922 17014 exclusion phecode
635.2
Antepartum hemorrhage, abruptio placentae, and
Antepartum hemorrhage, abruptio placentae, and placenta previa
 Pregnancy Complications 0.905 0.843 – 0.971 0.00568 848 8440 exclusion phecode
635.3 Placenta previa and abruptio placenta Pregnancy Complications 0.948 0.894 – 1 0.0719 1234 12059 exclusion phecode
636
Early or threatened labor; hemorrhage in early
Early or threatened labor; hemorrhage in early pregnancy
 Pregnancy Complications 0.998 0.956 – 1.04 0.925 2286 19568 exclusion phecode
636.2 Early onset of delivery Pregnancy Complications 1.03 0.948 – 1.12 0.482 593 6017 exclusion phecode
636.3 Hemorrhage in early pregnancy Pregnancy Complications 0.973 0.913 – 1.04 0.398 1049 10542 exclusion phecode
638 Other high-risk pregnancy Pregnancy Complications 0.901 0.704 – 1.15 0.41 67 686 exclusion phecode
642
Hypertension complicating pregnancy
Hypertension complicating pregnancy, childbirth, and the puerperium
 Pregnancy Complications 1.05 0.984 – 1.12 0.142 1053 10847 exclusion phecode
642.1 Preeclampsia and eclampsia Pregnancy Complications 1.02 0.907 – 1.15 0.721 289 2990 exclusion phecode
643 Excessive vomiting in pregnancy Pregnancy Complications 0.962 0.832 – 1.11 0.594 203 2106 exclusion phecode
643.1 Hyperemesis gravidarum Pregnancy Complications 0.93 0.784 – 1.1 0.4 145 1496 exclusion phecode
645 Late pregnancy and failed induction Pregnancy Complications 0.938 0.884 – 0.995 0.0326 1221 12220 exclusion phecode
646 Other complications of pregnancy NEC Pregnancy Complications 0.99 0.947 – 1.04 0.671 2148 20439 exclusion phecode
647
Infectious and parasitic complications
Infectious and parasitic complications affecting pregnancy
 Pregnancy Complications 1.14 0.896 – 1.45 0.286 68 663 exclusion phecode
647.1
Infections of genitourinary tract during
Infections of genitourinary tract during pregnancy
 Pregnancy Complications 0.989 0.873 – 1.12 0.859 268 2698 exclusion phecode
649
Other conditions or status of the mother
Other conditions or status of the mother complicating pregnancy, childbirth, or the puerperium
 Pregnancy Complications 0.837 0.686 – 1.02 0.0777 107 1112 exclusion phecode
649.1
Diabetes or abnormal glucose tolerance
Diabetes or abnormal glucose tolerance complicating pregnancy
 Pregnancy Complications 1.15 0.876 – 1.52 0.307 50 1891 exclusion phecode
650 Normal delivery Pregnancy Complications 0.914 0.872 – 0.958 0.000194 1892 18558 exclusion phecode
651 Multiple gestation Pregnancy Complications 0.985 0.88 – 1.1 0.8 338 3390 exclusion phecode
652
Malposition and malpresentation of fetus or
Malposition and malpresentation of fetus or obstruction
 Pregnancy Complications 0.991 0.943 – 1.04 0.732 1675 16191 exclusion phecode
653
Problems associated with amniotic cavity and
Problems associated with amniotic cavity and membranes
 Pregnancy Complications 0.953 0.902 – 1.01 0.0891 1371 13371 exclusion phecode
654
Other and unspecified complications of birth
Other and unspecified complications of birth; puerperium affecting management of mother
 Pregnancy Complications 0.953 0.753 – 1.21 0.69 72 727 exclusion phecode
655
Known or suspected fetal abnormality affecting
Known or suspected fetal abnormality affecting management of mother
 Pregnancy Complications 0.953 0.922 – 0.984 0.00377 4192 28851 exclusion phecode
656 Other perinatal conditions of fetus or newborn Pregnancy Complications 1 0.823 – 1.22 0.986 105 1051 exclusion phecode
661 Fetal distress and abnormal forces of labor Pregnancy Complications 0.938 0.898 – 0.981 0.00492 2210 18007 exclusion phecode
663
Umbilical cord complications during labor and
Umbilical cord complications during labor and delivery
 Pregnancy Complications 0.971 0.889 – 1.06 0.525 517 5194 exclusion phecode
665 Obstetrical/birth trauma Pregnancy Complications 0.93 0.903 – 0.959 2.55e-06 5235 28815 exclusion phecode
669 Complications of labor and delivery NEC Pregnancy Complications 0.943 0.904 – 0.983 0.00551 2502 20734 exclusion phecode
671
Venous/cerebrovascular complications embolism
Venous/cerebrovascular complications embolism in pregnancy and the puerperium
 Pregnancy Complications 0.987 0.842 – 1.16 0.876 158 1586 exclusion phecode
674 Other complications of the puerperium NEC Pregnancy Complications 1.07 0.935 – 1.21 0.344 251 2547 exclusion phecode
676
Other disorders of the breast associated with
Other disorders of the breast associated with childbirth and disorders of lactation
 Pregnancy Complications 1 0.775 – 1.3 0.985 63 609 exclusion phecode
679 Complications of in utero procedures Dermatologic 0.794 0.604 – 1.04 0.0996 51 514 exclusion phecode
681 Superficial cellulitis and abscess Dermatologic 1.08 1.05 – 1.11 1.74e-08 6104 67994 exclusion phecode
681.1 Cellulitis and abscess of fingers/toes Dermatologic 1.03 0.934 – 1.13 0.586 473 5322 exclusion phecode
681.2 Cellulitis and abscess of face/neck Dermatologic 1.1 1.01 – 1.21 0.0389 474 4941 exclusion phecode
681.3 Cellulitis and abscess of arm/hand Dermatologic 1.08 1.05 – 1.11 1.31e-06 4576 51689 exclusion phecode
681.5 Cellulitis and abscess of leg, except foot Dermatologic 1.08 1.05 – 1.12 2.96e-07 4581 51745 exclusion phecode
681.6 Cellulitis and abscess of foot, toe Dermatologic 1.08 1.05 – 1.11 1.04e-06 4541 51336 exclusion phecode
681.7 Cellulitis and abscess of trunk Dermatologic 1.1 1.01 – 1.2 0.0351 524 5692 exclusion phecode
686
Other local infections of skin and subcutaneous
Other local infections of skin and subcutaneous tissue
 Dermatologic 1.1 1.04 – 1.17 0.00177 1124 12646 exclusion phecode
686.1 Carbuncle and furuncle Dermatologic 1.11 1.06 – 1.16 1.55e-05 1948 21676 exclusion phecode
686.3 Pilonidal cyst Dermatologic 1.07 0.974 – 1.17 0.169 524 5552 exclusion phecode
686.4 Pyogenic granuloma Dermatologic 1.07 0.954 – 1.2 0.251 328 3429 exclusion phecode
687 Symptoms affecting skin Dermatologic 1.05 0.96 – 1.16 0.274 498 5216 exclusion phecode
687.1 Rash and other nonspecific skin eruption Dermatologic 1.04 0.993 – 1.09 0.095 1945 20296 exclusion phecode
687.2 Localized superficial swelling, mass, or lump Dermatologic 1.11 0.974 – 1.26 0.122 264 2692 exclusion phecode
687.3 Changes in skin texture Dermatologic 0.889 0.727 – 1.09 0.25 103 1007 exclusion phecode
687.4 Disturbance of skin sensation Dermatologic 1.12 1.07 – 1.16 9.03e-08 2637 27337 exclusion phecode
689 Disorder of skin and subcutaneous tissue NOS Dermatologic 1.03 0.997 – 1.05 0.0822 5340 54233 exclusion phecode
690 Erythematosquamous dermatosis Dermatologic 0.925 0.712 – 1.2 0.562 63 652 exclusion phecode
690.1 Seborrheic dermatitis Dermatologic 0.983 0.729 – 1.32 0.908 46 494 exclusion phecode
691 Congenital anomalies of skin Dermatologic 1.02 0.845 – 1.24 0.819 112 1120 exclusion phecode
694 Dyschromia and Vitiligo Dermatologic 1.02 0.949 – 1.09 0.651 924 9323 exclusion phecode
694.1 Vitiligo Dermatologic 0.988 0.751 – 1.3 0.932 52 567 exclusion phecode
694.2 Other dyschromia Dermatologic 1.01 0.937 – 1.09 0.791 748 7415 exclusion phecode
694.3 Vascular disorders of skin Dermatologic 1.02 0.831 – 1.25 0.865 99 1104 exclusion phecode
695 Erythematous conditions Dermatologic 1.08 1.04 – 1.13 0.000391 2170 22502 exclusion phecode
695.1 Toxic erythema Dermatologic 1.18 0.968 – 1.44 0.101 102 1042 exclusion phecode
695.2 Bullous dermatoses Dermatologic 1.04 0.866 – 1.25 0.666 121 1271 exclusion phecode
695.21 Dermatitis herpetiformis Dermatologic 1.11 0.848 – 1.46 0.441 51 526 exclusion phecode
695.22 Pemphigus and pemphigoid Dermatologic 0.922 0.717 – 1.19 0.527 64 682 exclusion phecode
695.3 Rosacea Dermatologic 1.17 1.04 – 1.33 0.0108 283 2885 exclusion phecode
695.4 Lupus (localized and systemic) Dermatologic 1.01 0.909 – 1.12 0.878 391 3938 exclusion phecode
695.41 Cutaneous lupus erythematosus Dermatologic 0.974 0.81 – 1.17 0.778 124 1232 exclusion phecode
695.42 Systemic lupus erythematosus Dermatologic 1.03 0.917 – 1.15 0.655 323 3265 exclusion phecode
695.7 Prurigo and Lichen Dermatologic 1.06 0.982 – 1.15 0.137 706 7357 exclusion phecode
695.8 Other specified erythematous conditions Dermatologic 1.2 1.04 – 1.38 0.0115 210 2244 exclusion phecode
695.81 Erythema nodosum Dermatologic 1.27 0.997 – 1.62 0.0526 71 730 exclusion phecode
695.9 Unspecified erythematous condition Dermatologic 1.05 0.945 – 1.16 0.392 417 4368 exclusion phecode
696 Psoriasis and related disorders Dermatologic 1.13 1.08 – 1.18 2.15e-07 1999 21181 exclusion phecode
696.4 Psoriasis Dermatologic 1.13 1.08 – 1.19 1.69e-07 1949 20688 exclusion phecode
696.41 Psoriasis vulgaris Dermatologic 1.15 1.09 – 1.21 4.88e-07 1482 15771 exclusion phecode
696.42 Psoriatic arthropathy Dermatologic 1.09 1 – 1.18 0.0494 627 6658 exclusion phecode
697 Sarcoidosis Dermatologic 1.12 1.02 – 1.23 0.0191 487 5093 exclusion phecode
698 Pruritus and related conditions Dermatologic 1.13 1.04 – 1.22 0.0025 713 7402 exclusion phecode
700 Corns and callosities Dermatologic 1.03 0.912 – 1.17 0.614 268 2749 exclusion phecode
701
Other hypertrophic and atrophic conditions of
Other hypertrophic and atrophic conditions of skin
 Dermatologic 1.02 0.992 – 1.06 0.152 4339 44148 exclusion phecode
701.1 Keratoderma, acquired Dermatologic 1.08 0.861 – 1.35 0.504 81 797 exclusion phecode
701.2 Scar conditions and fibrosis of skin Dermatologic 1.01 0.971 – 1.06 0.531 2223 22237 exclusion phecode
701.3 Circumscribed scleroderma Dermatologic 1.23 0.929 – 1.63 0.148 54 587 exclusion phecode
701.4 Keloid scar Dermatologic 0.992 0.86 – 1.15 0.915 202 2074 exclusion phecode
701.5 Abnormal granulation tissue Dermatologic 0.98 0.888 – 1.08 0.686 422 4348 exclusion phecode
701.6 Acquired acanthosis nigricans Dermatologic 1.09 0.877 – 1.35 0.443 92 974 exclusion phecode
702
Degenerative skin conditions and other
Degenerative skin conditions and other dermatoses
 Dermatologic 1 0.976 – 1.03 0.783 5152 51237 exclusion phecode
702.1 Actinic keratosis Dermatologic 0.987 0.946 – 1.03 0.529 2428 24225 exclusion phecode
702.2 Seborrheic keratosis Dermatologic 1.02 0.983 – 1.06 0.291 2921 28890 exclusion phecode
703 Diseases of nail, NOS Dermatologic 1.03 0.916 – 1.15 0.638 320 3332 exclusion phecode
703.1 Ingrowing nail Dermatologic 1.06 0.984 – 1.14 0.129 838 9124 exclusion phecode
704 Diseases of hair and hair follicles Dermatologic 1.08 1.05 – 1.11 1.4e-07 4979 49801 exclusion phecode
704.1 Alopecia Dermatologic 1.2 0.997 – 1.44 0.0542 117 1225 exclusion phecode
704.8
Other specified diseases of hair and hair
Other specified diseases of hair and hair follicles
 Dermatologic 1.19 0.931 – 1.52 0.165 74 717 exclusion phecode
705 Disorders of sweat glands Dermatologic 1.15 0.996 – 1.34 0.0568 201 2187 exclusion phecode
705.3 Hidradenitis Dermatologic 1.24 1.05 – 1.46 0.0101 164 1796 exclusion phecode
705.8 Hyperhidrosis Dermatologic 1.11 1.01 – 1.21 0.0251 540 5540 exclusion phecode
706 Diseases of sebaceous glands Dermatologic 1.07 1.04 – 1.09 3.53e-08 7841 78625 exclusion phecode
706.1 Acne Dermatologic 0.977 0.775 – 1.23 0.844 73 733 exclusion phecode
706.2 Sebaceous cyst Dermatologic 1.07 1.04 – 1.09 1.21e-08 8282 83006 exclusion phecode
707 Chronic ulcer of skin Dermatologic 1.1 1.04 – 1.16 0.000588 1374 18299 exclusion phecode
707.1 Decubitus ulcer Dermatologic 1.07 0.994 – 1.16 0.0697 727 8446 exclusion phecode
709 Diffuse diseases of connective tissue Dermatologic 1.1 1.06 – 1.14 3.28e-07 3018 32437 exclusion phecode
709.2 Sicca syndrome Dermatologic 1.08 0.983 – 1.18 0.11 479 4856 exclusion phecode
709.3 Systemic sclerosis Dermatologic 1.1 0.935 – 1.29 0.253 163 1671 exclusion phecode
709.6
Other specified diffuse diseases of connective
Other specified diffuse diseases of connective tissue
 Dermatologic 1.17 0.903 – 1.51 0.237 61 614 exclusion phecode
709.7 Unspecified diffuse connective tissue disease Dermatologic 1.11 1.07 – 1.16 1.01e-06 2346 25597 exclusion phecode
710
Osteomyelitis, periostitis, and other
Osteomyelitis, periostitis, and other infections involving bone
 Musculoskeletal 1.19 1.07 – 1.31 0.000838 427 5631 exclusion phecode
710.1 Osteomyelitis Musculoskeletal 1.21 1.09 – 1.34 0.000348 387 5206 exclusion phecode
710.12 Chronic osteomyelitis Musculoskeletal 1.16 0.98 – 1.36 0.0846 154 1841 exclusion phecode
710.19 Unspecified osteomyelitis Musculoskeletal 1.21 1.07 – 1.38 0.00337 253 3710 exclusion phecode
711 Arthropathy associated with infections Musculoskeletal 1.05 0.945 – 1.17 0.362 368 3990 exclusion phecode
711.1 Pyogenic arthritis Musculoskeletal 1.11 0.978 – 1.25 0.11 282 3105 exclusion phecode
712 Infective connective tissue disorders Musculoskeletal 1.32 1.03 – 1.68 0.0285 73 758 exclusion phecode
713
Arthropathy associated with other disorders
Arthropathy associated with other disorders classified elsewhere
 Musculoskeletal 0.916 0.734 – 1.14 0.44 81 1415 exclusion phecode
713.5
Arthropathy associated with neurological
Arthropathy associated with neurological disorders
 Musculoskeletal 2.72 1.3 – 5.68 0.00793 6 620 exclusion phecode
714
Rheumatoid arthritis and other inflammatory
Rheumatoid arthritis and other inflammatory polyarthropathies
 Musculoskeletal 1.16 1.13 – 1.2 4.93e-21 4357 45792 exclusion phecode
714.1 Rheumatoid arthritis Musculoskeletal 1.16 1.13 – 1.2 9.72e-20 3953 41437 exclusion phecode
715 Other inflammatory spondylopathies Musculoskeletal 1.15 1.09 – 1.22 1.65e-07 1511 15657 exclusion phecode
715.1 Sacroiliitis NEC Musculoskeletal 1.05 0.867 – 1.27 0.612 106 1087 exclusion phecode
715.2 Ankylosing spondylitis Musculoskeletal 1.12 1.03 – 1.23 0.00907 567 5804 exclusion phecode
716 Other arthropathies Musculoskeletal 1.12 1.11 – 1.13 9.52e-86 34189 251534 exclusion phecode
716.1 Unspecified polyarthropathy or polyarthritis Musculoskeletal 1.16 1.12 – 1.2 5.86e-15 3136 33100 exclusion phecode
716.2 Unspecified monoarthritis Musculoskeletal 1.13 1.11 – 1.15 1.11e-42 14255 146413 exclusion phecode
716.9 Arthropathy NOS Musculoskeletal 1.12 1.11 – 1.13 5.63e-83 32782 248570 exclusion phecode
717 Polymyalgia Rheumatica Musculoskeletal 1.12 1.05 – 1.19 0.000464 1056 10755 exclusion phecode
720 Spinal stenosis Musculoskeletal 1.13 1.09 – 1.17 5.76e-11 3327 34811 exclusion phecode
721 Spondylosis and allied disorders Musculoskeletal 1.12 1.1 – 1.15 1.62e-20 7082 73821 exclusion phecode
721.1 Spondylosis without myelopathy Musculoskeletal 1.13 1.1 – 1.16 3.26e-15 4568 47580 exclusion phecode
721.2 Spondylosis with myelopathy Musculoskeletal 1.22 1.04 – 1.43 0.0163 162 1779 exclusion phecode
721.8 Other allied disorders of spine Musculoskeletal 1.12 0.999 – 1.26 0.0516 322 3334 exclusion phecode
722 Intervertebral disc disorders Musculoskeletal 1.12 1.09 – 1.15 1.11e-22 8258 85149 exclusion phecode
722.1 Displacement of intervertebral disc Musculoskeletal 1.14 1.03 – 1.25 0.00756 469 4833 exclusion phecode
722.6 Degeneration of intervertebral disc Musculoskeletal 1.15 1.1 – 1.2 2.82e-11 2598 26876 exclusion phecode
722.8 Postlaminectomy syndrome Musculoskeletal 1.31 1.02 – 1.7 0.0377 65 636 exclusion phecode
722.9 Other and unspecified disc disorder Musculoskeletal 1.1 1.07 – 1.14 5.75e-09 4073 41781 exclusion phecode
723 Other disorders of cervical region Musculoskeletal 1.21 1.1 – 1.33 8.86e-05 475 4864 exclusion phecode
723.1 Torticollis Musculoskeletal 1.24 1.01 – 1.52 0.0366 100 1017 exclusion phecode
724 Other and unspecified disorders of back Musculoskeletal 1.1 1.05 – 1.15 0.000141 1902 19394 exclusion phecode
724.1 Disorders of sacrum Musculoskeletal 1.2 1.08 – 1.33 0.000542 383 3847 exclusion phecode
724.2 Disorders of coccyx Musculoskeletal 1.19 1.08 – 1.32 0.000793 386 3872 exclusion phecode
724.8 Other symptoms referable to back Musculoskeletal 1.51 1.15 – 2 0.00342 57 606 exclusion phecode
724.9 Other unspecified back disorders Musculoskeletal 1.06 1 – 1.11 0.044 1490 15196 exclusion phecode
726 Peripheral enthesopathies and allied syndromes Musculoskeletal 1.1 1.08 – 1.12 2.14e-27 13398 138816 exclusion phecode
726.1 Enthesopathy Musculoskeletal 1.1 1.08 – 1.13 6.09e-18 8757 90645 exclusion phecode
726.2 Synoviopathy Musculoskeletal 1.29 1.14 – 1.45 2.8e-05 308 3177 exclusion phecode
726.3 Bursitis Musculoskeletal 1.11 1.03 – 1.2 0.00459 765 8075 exclusion phecode
727 Other disorders of synovium, tendon, and bursa Musculoskeletal 1.09 1.06 – 1.11 9.73e-11 6854 69603 exclusion phecode
727.1 Synovitis and tenosynovitis Musculoskeletal 1.09 1.05 – 1.14 1.44e-05 2522 26036 exclusion phecode
727.2 Bursitis disorders Musculoskeletal 1.05 0.852 – 1.29 0.666 92 978 exclusion phecode
727.4 Ganglion and cyst of synovium, tendon, and bursa Musculoskeletal 1.06 1.02 – 1.1 0.00152 2939 29661 exclusion phecode
727.5 Rupture of synovium Musculoskeletal 1.05 0.96 – 1.15 0.289 542 5507 exclusion phecode
727.6 Rupture of tendon, nontraumatic Musculoskeletal 1.16 1.03 – 1.3 0.0114 330 3313 exclusion phecode
727.7 Contracture of tendon (sheath) Musculoskeletal 1.13 0.948 – 1.34 0.173 136 1360 exclusion phecode
728 Disorders of muscle, ligament, and fascia Musculoskeletal 1.07 1.03 – 1.11 0.000218 3324 34058 exclusion phecode
728.2 Laxity of ligament or hypermobility syndrome Musculoskeletal 1.05 0.944 – 1.16 0.383 395 3962 exclusion phecode
728.7 Fasciitis Musculoskeletal 1.07 1.04 – 1.11 7.38e-05 3444 35266 exclusion phecode
728.71
Contracture of palmar fascia [Dupuytren's
Contracture of palmar fascia [Dupuytren's disease]
 Musculoskeletal 1.07 1.03 – 1.11 0.000194 3141 32186 exclusion phecode
729 Other disorders of soft tissues Musculoskeletal 1.13 1.1 – 1.17 6.7e-19 5430 57052 exclusion phecode
729.1 Rheumatism, unspecified and fibrositis Musculoskeletal 1.13 1.06 – 1.21 0.000374 906 9645 exclusion phecode
729.3 Panniculitis Musculoskeletal 0.978 0.796 – 1.2 0.833 93 966 exclusion phecode
731
Osteitis deformans and osteopathies associated
Osteitis deformans and osteopathies associated with other disorders classified elsewhere
 Musculoskeletal 1.2 1.06 – 1.36 0.00511 257 2633 exclusion phecode
731.1 Osteitis deformans [Paget's disease of bone] Musculoskeletal 1.2 1.05 – 1.37 0.00686 243 2487 exclusion phecode
732 Osteochondropathies Musculoskeletal 1.1 0.993 – 1.21 0.0681 447 4441 exclusion phecode
732.1 Juvenile osteochondrosis Musculoskeletal 1.14 0.978 – 1.32 0.0943 195 1952 exclusion phecode
732.7 Osteochondritis dissecans Musculoskeletal 0.97 0.74 – 1.27 0.822 57 541 exclusion phecode
733 Other disorders of bone and cartilage Musculoskeletal 1.03 0.981 – 1.09 0.224 1668 16864 exclusion phecode
733.2 Cyst of bone Musculoskeletal 1.08 0.962 – 1.22 0.186 299 2943 exclusion phecode
733.4 Aseptic necrosis of bone Musculoskeletal 1.05 0.96 – 1.15 0.277 499 5091 exclusion phecode
733.6 Costochondritis Musculoskeletal 1.18 0.98 – 1.41 0.0819 122 1218 exclusion phecode
733.8 Malunion and nonunion of fracture Musculoskeletal 1.04 0.98 – 1.11 0.19 1154 11673 exclusion phecode
733.9 Chondromalacia Musculoskeletal 1.11 0.916 – 1.34 0.287 114 1150 exclusion phecode
735 Acquired foot deformities Musculoskeletal 1.04 1.02 – 1.06 0.000321 9254 91386 exclusion phecode
735.1 Flat foot Musculoskeletal 1.07 0.92 – 1.24 0.385 185 1810 exclusion phecode
735.2 Acquired toe deformities Musculoskeletal 1.05 1.02 – 1.09 0.000481 4866 48115 exclusion phecode
735.21 Hammer toe (acquired) Musculoskeletal 1.06 1.01 – 1.11 0.0247 1850 18337 exclusion phecode
735.23 Hallux rigidus Musculoskeletal 1.08 1.02 – 1.13 0.00675 1498 14710 exclusion phecode
735.3 Hallux valgus (Bunion) Musculoskeletal 1.02 0.992 – 1.04 0.173 6437 63406 exclusion phecode
736 Other acquired deformities of limbs Musculoskeletal 1.11 1.05 – 1.17 0.000126 1512 15264 exclusion phecode
736.2 Acquired deformities of finger Musculoskeletal 0.983 0.863 – 1.12 0.792 239 2337 exclusion phecode
737 Curvature of spine Musculoskeletal 1.02 0.961 – 1.09 0.467 1067 10715 exclusion phecode
737.3 Kyphoscoliosis and scoliosis Musculoskeletal 1.02 0.954 – 1.09 0.588 1008 10064 exclusion phecode
738 Other acquired musculoskeletal deformity Musculoskeletal 1.08 1.02 – 1.13 0.00386 1753 18065 exclusion phecode
738.4 Acquired spondylolisthesis Musculoskeletal 1.1 1.04 – 1.16 0.000831 1392 14362 exclusion phecode
739 Contracture of joint Musculoskeletal 1.06 0.962 – 1.17 0.235 454 4621 exclusion phecode
740 Osteoarthrosis Musculoskeletal 1.09 1.08 – 1.1 1.86e-38 25395 218276 exclusion phecode
740.1 Osteoarthritis; localized Musculoskeletal 1.08 1.07 – 1.1 8.92e-23 16122 159216 exclusion phecode
740.11 Osteoarthrosis, localized, primary Musculoskeletal 1.1 1.07 – 1.12 2.08e-15 8251 84140 exclusion phecode
740.12 Osteoarthrosis, localized, secondary Musculoskeletal 1 0.893 – 1.12 0.995 327 3292 exclusion phecode
740.2 Osteoarthrosis, generalized Musculoskeletal 1.13 1.04 – 1.24 0.00514 551 5605 exclusion phecode
740.9 Osteoarthrosis NOS Musculoskeletal 1.11 1.09 – 1.13 2.45e-25 11062 115758 exclusion phecode
741 Symptoms and disorders of the joints Musculoskeletal 1.12 1.08 – 1.16 3.26e-09 3265 33551 exclusion phecode
741.1 Ankylosis of joint Musculoskeletal 1.28 1.04 – 1.57 0.0188 96 953 exclusion phecode
741.2 Stiffness of joint Musculoskeletal 1.14 1.05 – 1.24 0.00266 569 5806 exclusion phecode
741.3 Difficulty in walking Musculoskeletal 0.995 0.828 – 1.2 0.956 126 1431 exclusion phecode
741.4 Joint effusions Musculoskeletal 1.16 1.1 – 1.23 1.76e-07 1283 13289 exclusion phecode
741.5 Hemarthrosis Musculoskeletal 1.14 0.928 – 1.4 0.211 101 1036 exclusion phecode
741.6 Villonodular synovitis Musculoskeletal 0.987 0.747 – 1.3 0.926 51 514 exclusion phecode
742 Derangement of joint, non-traumatic Musculoskeletal 1.1 1.06 – 1.15 1.06e-06 2680 27102 exclusion phecode
742.1 Loose body in joint Musculoskeletal 1.09 0.973 – 1.22 0.137 315 3159 exclusion phecode
742.2
Pathological, developmental or recurrent
Pathological, developmental or recurrent dislocation
 Musculoskeletal 1.18 0.955 – 1.47 0.124 87 934 exclusion phecode
742.8 Articular cartilage disorder Musculoskeletal 1.16 1.05 – 1.27 0.00227 459 4762 exclusion phecode
742.9 Other derangement of joint Musculoskeletal 1.1 1.05 – 1.15 6.46e-05 1898 19016 exclusion phecode
743
Osteoporosis, osteopenia and pathological
Osteoporosis, osteopenia and pathological fracture
 Musculoskeletal 1.01 0.983 – 1.03 0.539 7063 71598 exclusion phecode
743.1 Osteoporosis Musculoskeletal 1 0.974 – 1.03 0.989 5975 60607 exclusion phecode
743.11 Osteoporosis NOS Musculoskeletal 1 0.975 – 1.03 0.825 5187 52642 exclusion phecode
743.13 Other specified osteoporosis Musculoskeletal 1.08 0.981 – 1.19 0.116 487 4960 exclusion phecode
743.2 Pathologic fracture Musculoskeletal 1.04 0.949 – 1.14 0.385 470 4849 exclusion phecode
743.9
Osteopenia or other disorder of bone and
Osteopenia or other disorder of bone and cartilage
 Musculoskeletal 1.02 0.952 – 1.1 0.515 771 7736 exclusion phecode
745 Pain in joint Musculoskeletal 1.11 1.08 – 1.14 9e-18 7314 75549 exclusion phecode
747 Cardiac and circulatory congenital anomalies Congenital Anomalies 1.09 1.04 – 1.13 0.000109 2444 26246 exclusion phecode
747.1 Cardiac congenital anomalies Congenital Anomalies 1.09 1.04 – 1.14 8.84e-05 2282 24611 exclusion phecode
747.11 Cardiac shunt/ heart septal defect Congenital Anomalies 0.962 0.88 – 1.05 0.394 552 5570 exclusion phecode
747.12 Valvular heart disease/ heart chambers Congenital Anomalies 1.03 0.891 – 1.18 0.725 222 2232 exclusion phecode
747.13 Congenital anomalies of great vessels Congenital Anomalies 1.15 1.09 – 1.21 1.38e-07 1517 16840 exclusion phecode
747.2
Congenital anomalies of peripheral vascular
Congenital anomalies of peripheral vascular system
 Congenital Anomalies 1.04 0.883 – 1.23 0.623 154 1589 exclusion phecode
748 Anomalies of respiratory system, congenital Congenital Anomalies 1.13 0.86 – 1.48 0.385 49 479 exclusion phecode
749 Congenital anomalies of face and neck Congenital Anomalies 0.904 0.803 – 1.02 0.0987 282 2892 exclusion phecode
750 Digestive congenital anomalies Congenital Anomalies 0.95 0.876 – 1.03 0.217 646 6422 exclusion phecode
750.1 Upper gastrointestinal congenital anomalies Congenital Anomalies 0.888 0.79 – 0.998 0.0464 304 3046 exclusion phecode
750.13 Congenital anomalies of mouth/tongue Congenital Anomalies 0.87 0.747 – 1.01 0.075 182 1772 exclusion phecode
750.2 Lower gastrointestinal congenital anomalies Congenital Anomalies 1.01 0.902 – 1.13 0.868 338 3363 exclusion phecode
750.21 Congenital anomalies of intestine Congenital Anomalies 0.982 0.855 – 1.13 0.797 217 2115 exclusion phecode
750.22
Congenital anomaly of gallbladder, bile ducts
Congenital anomaly of gallbladder, bile ducts, liver, pancreas
 Congenital Anomalies 1.07 0.876 – 1.31 0.511 110 1119 exclusion phecode
751 Genitourinary congenital anomalies Congenital Anomalies 0.975 0.924 – 1.03 0.368 1418 14452 exclusion phecode
751.1 Congenital anomalies of genital organs Congenital Anomalies 0.969 0.894 – 1.05 0.436 661 6602 exclusion phecode
751.11 Congenital anomalies of female genital organs Congenital Anomalies 0.997 0.905 – 1.1 0.958 442 4394 exclusion phecode
751.12 Congenital anomalies of male genital organs Congenital Anomalies 0.906 0.784 – 1.05 0.18 202 2042 exclusion phecode
751.2 Congenital anomalies of urinary system Congenital Anomalies 0.998 0.927 – 1.07 0.95 759 7863 exclusion phecode
751.21 Cystic kidney disease Congenital Anomalies 0.961 0.865 – 1.07 0.451 380 3981 exclusion phecode
751.22 Other specified congenital anomalies of kidney Congenital Anomalies 1.03 0.92 – 1.16 0.576 301 3141 exclusion phecode
752 Nervous system congenital anomalies Congenital Anomalies 1.16 1.03 – 1.3 0.0145 310 3151 exclusion phecode
752.1 Neural tube defects Congenital Anomalies 1.1 0.961 – 1.25 0.169 242 2440 exclusion phecode
752.11 Spina bifida Congenital Anomalies 1.08 0.935 – 1.24 0.302 201 2013 exclusion phecode
752.2
Other specified congenital anomalies of nervous
Other specified congenital anomalies of nervous system
 Congenital Anomalies 1.3 1.02 – 1.66 0.0335 71 739 exclusion phecode
753 Congenital anomalies of the eye Congenital Anomalies 1.25 1.02 – 1.52 0.0292 120 1197 exclusion phecode
753.1 Congenital cataract and lens anomalies Congenital Anomalies 1.28 0.976 – 1.67 0.0748 72 716 exclusion phecode
754 Congenital musculoskeletal deformities of spine Congenital Anomalies 1.13 0.924 – 1.38 0.236 103 1041 exclusion phecode
755 Congenital anomalies of limbs Congenital Anomalies 1.11 1 – 1.22 0.0459 408 4087 exclusion phecode
755.1 Congenital deformities of feet Congenital Anomalies 1.09 0.946 – 1.26 0.23 193 1984 exclusion phecode
755.6
Other congenital anomalies of lower limb
Other congenital anomalies of lower limb, including pelvic girdle
 Congenital Anomalies 1.1 0.938 – 1.29 0.241 159 1556 exclusion phecode
755.61 Congenital hip dysplasia and deformity Congenital Anomalies 1.08 0.884 – 1.31 0.459 106 1033 exclusion phecode
756 Other congenital musculoskeletal anomalies Congenital Anomalies 1.04 0.951 – 1.13 0.405 553 5548 exclusion phecode
756.3
Congenital anomalies of muscle, tendon, fascia
Congenital anomalies of muscle, tendon, fascia, and connective tissue
 Congenital Anomalies 1.02 0.81 – 1.29 0.863 78 768 exclusion phecode
756.5 Congenital osteodystrophies Congenital Anomalies 1.06 0.961 – 1.18 0.232 408 4121 exclusion phecode
758 Chromosomal anomalies and genetic disorders Congenital Anomalies 0.929 0.785 – 1.1 0.395 142 1619 exclusion phecode
758.1 Chromosomal anomalies Congenital Anomalies 0.929 0.719 – 1.2 0.573 57 793 exclusion phecode
759 Other and unspecified congenital anomalies Congenital Anomalies 1.01 0.875 – 1.16 0.908 204 2055 exclusion phecode
759.1 Anomalies of endocrine glands, congenital Congenital Anomalies 0.928 0.754 – 1.14 0.482 91 912 exclusion phecode
760 Back pain Symptoms 1.11 1.09 – 1.14 3.89e-25 10118 105492 exclusion phecode
761 Cervicalgia Symptoms 1.1 1.05 – 1.16 0.000133 1629 16951 exclusion phecode
764 Sciatica Symptoms 1.14 1.09 – 1.19 6.51e-09 2185 22486 exclusion phecode
766 Neuralgia, neuritis, and radiculitis NOS Symptoms 1.07 1 – 1.14 0.04 1070 11115 exclusion phecode
770 Myalgia and myositis unspecified Symptoms 1.09 1 – 1.19 0.0422 569 5994 exclusion phecode
771 Musculoskeletal symptoms referable to limbs Symptoms 1.09 1.02 – 1.18 0.017 778 8187 exclusion phecode
771.1 Swelling of limb Symptoms 1.13 1.1 – 1.17 3.31e-14 4161 43631 exclusion phecode
772 Symptoms of the muscles Symptoms 1.06 0.971 – 1.15 0.199 584 6195 exclusion phecode
773 Pain in limb Symptoms 1.11 1.08 – 1.14 5.86e-13 5628 58848 exclusion phecode
780 Hypothermia/Chills Symptoms 1.04 0.875 – 1.23 0.663 140 1635 exclusion phecode
781
Symptoms involving nervous and musculoskeletal
Symptoms involving nervous and musculoskeletal systems
 Symptoms 1.1 1.05 – 1.16 0.000111 1659 17686 exclusion phecode
782.3 Edema Symptoms 1.09 1.03 – 1.15 0.00178 1365 15365 exclusion phecode
782.6 Pallor and flushing Symptoms 1.06 0.9 – 1.24 0.501 153 1650 exclusion phecode
783 Fever of unknown origin Symptoms 1.05 1.01 – 1.08 0.00786 3539 36765 exclusion phecode
785 Abdominal pain Symptoms 1.06 1.05 – 1.07 4.71e-27 37406 286103 exclusion phecode
788 Syncope and collapse Symptoms 1.07 1.04 – 1.09 4.45e-08 8117 85154 exclusion phecode
789 Nausea and vomiting Symptoms 1.07 1.05 – 1.1 2.71e-12 10410 109905 exclusion phecode
790 Nonspecific findings on examination of blood Symptoms 1.02 0.865 – 1.21 0.776 141 1405 exclusion phecode
790.1 Elevated sedimentation rate Symptoms 1.25 1 – 1.56 0.0496 76 782 exclusion phecode
790.6 Other abnormal blood chemistry Symptoms 1.04 1.01 – 1.07 0.00565 5705 58767 exclusion phecode
791 Gangrene Symptoms 1.21 1.09 – 1.34 0.000309 382 5152 exclusion phecode
792
Abnormal Papanicolaou smear of cervix and
Abnormal Papanicolaou smear of cervix and cervical HPV
 Symptoms 0.909 0.739 – 1.12 0.371 95 925 exclusion phecode
793
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of musculoskeletal system
 Symptoms 0.939 0.78 – 1.13 0.509 116 1249 exclusion phecode
793.2
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of other intrathoracic organs (echocardiogram, etc)
 Symptoms 1.03 0.944 – 1.13 0.493 520 5317 exclusion phecode
794
Abnormal results of other function studies
Abnormal results of other function studies (bladder, pancreas, placenta, spleen, etc)
 Symptoms 0.837 0.69 – 1.02 0.0724 113 1158 exclusion phecode
797 Shock Symptoms 0.9 0.75 – 1.08 0.258 126 1455 exclusion phecode
797.1 Cardiogenic shock Symptoms 0.982 0.777 – 1.24 0.88 75 944 exclusion phecode
798 Malaise and fatigue Symptoms 1.08 1.04 – 1.12 2.62e-05 3074 32254 exclusion phecode
798.1 Chronic fatigue syndrome Symptoms 1.05 0.963 – 1.15 0.265 548 5681 exclusion phecode
800 Fracture of lower limb Injuries & Poisonings 1.05 1.02 – 1.08 0.00021 6478 66496 exclusion phecode
800.1 Fracture of neck of femur Injuries & Poisonings 0.971 0.924 – 1.02 0.254 1668 17025 exclusion phecode
800.2 Fracture of unspecified part of femur Injuries & Poisonings 1.06 0.904 – 1.25 0.452 151 1587 exclusion phecode
800.3 Fracture of tibia and fibula Injuries & Poisonings 1.06 1.01 – 1.11 0.0171 2001 20477 exclusion phecode
800.4 Fracture of patella Injuries & Poisonings 1.08 1 – 1.17 0.0457 709 7196 exclusion phecode
801 Fracture of ankle and foot Injuries & Poisonings 1.07 1.03 – 1.12 0.00238 2048 20884 exclusion phecode
801.1 Fracture of foot Injuries & Poisonings 1.05 1 – 1.1 0.0487 1708 17374 exclusion phecode
802 Fracture of pelvis Injuries & Poisonings 0.991 0.916 – 1.07 0.817 675 6757 exclusion phecode
803 Fracture of upper limb Injuries & Poisonings 0.98 0.957 – 1 0.0865 7835 78638 exclusion phecode
803.1 Fracture of humerus Injuries & Poisonings 1.01 0.957 – 1.06 0.751 1532 15970 exclusion phecode
803.2 Fracture of radius and ulna Injuries & Poisonings 0.958 0.93 – 0.986 0.00359 5004 49646 exclusion phecode
803.3 Fracture of clavicle or scapula Injuries & Poisonings 1.01 0.96 – 1.07 0.617 1422 14317 exclusion phecode
804 Fracture of hand or wrist Injuries & Poisonings 1 0.967 – 1.04 0.89 3172 31635 exclusion phecode
805
Fracture of vertebral column without mention of
Fracture of vertebral column without mention of spinal cord injury
 Injuries & Poisonings 1.05 0.991 – 1.11 0.095 1253 12743 exclusion phecode
807 Fracture of ribs Injuries & Poisonings 1.02 0.944 – 1.1 0.636 723 7285 exclusion phecode
809 Fracture of unspecified bones Injuries & Poisonings 1 0.946 – 1.07 0.888 1195 12215 exclusion phecode
817 Concussion Injuries & Poisonings 0.962 0.838 – 1.1 0.582 228 2295 exclusion phecode
818 Intracranial hemorrhage (injury) Injuries & Poisonings 1.05 0.952 – 1.15 0.35 469 4844 exclusion phecode
819
Skull and face fracture and other intercranial
Skull and face fracture and other intercranial injury
 Injuries & Poisonings 1.01 0.975 – 1.05 0.488 2780 27999 exclusion phecode
823 Torus fracture Injuries & Poisonings 1.03 0.979 – 1.09 0.245 1553 15891 exclusion phecode
830 Dislocation Injuries & Poisonings 1.03 0.987 – 1.08 0.158 1981 19750 exclusion phecode
835 Internal derangement of knee Injuries & Poisonings 1.08 1.06 – 1.1 2.04e-18 14368 143917 exclusion phecode
836 Traumatic arthropathy Injuries & Poisonings 1.16 1.06 – 1.27 0.00181 489 4961 exclusion phecode
840 Sprains and strains Injuries & Poisonings 1.04 0.943 – 1.14 0.448 455 4463 exclusion phecode
850 Hemorrhage or hematoma complicating a procedure Injuries & Poisonings 1.1 1.06 – 1.13 1.61e-09 4831 49685 exclusion phecode
851
Complications of transplants and reattached
Complications of transplants and reattached limbs
 Injuries & Poisonings 1.11 0.935 – 1.32 0.23 142 1484 exclusion phecode
853 Complication of colostomy or enterostomy Injuries & Poisonings 1.15 1.04 – 1.26 0.00477 445 4715 exclusion phecode
854
Complications of cardiac/vascular device
Complications of cardiac/vascular device, implant, and graft
 Injuries & Poisonings 1.09 1.03 – 1.15 0.0016 1490 16959 exclusion phecode
857
Mechanical complication of unspecified
Mechanical complication of unspecified genitourinary device, implant, and graft
 Injuries & Poisonings 1.04 0.978 – 1.11 0.206 1115 11686 exclusion phecode
858 Complication of internal orthopedic device Injuries & Poisonings 1.11 1.07 – 1.15 8.24e-08 2928 29749 exclusion phecode
859
Complication due to other implant and internal
Complication due to other implant and internal device
 Injuries & Poisonings 1.1 1.06 – 1.14 1.57e-06 2992 30725 exclusion phecode
860 Bone marrow or stem cell transplant Neoplasms 0.942 0.72 – 1.23 0.662 63 644 exclusion phecode
870 Open wounds of head; neck; and trunk Injuries & Poisonings 1.04 0.999 – 1.07 0.0534 3232 32981 exclusion phecode
870.1 Open wound or laceration of eye or eyelid Injuries & Poisonings 1.06 0.93 – 1.2 0.402 253 2529 exclusion phecode
870.2 Open wound of ear Injuries & Poisonings 0.976 0.837 – 1.14 0.755 179 1833 exclusion phecode
870.3 Other open wound of head and face Injuries & Poisonings 1.03 0.992 – 1.07 0.122 2688 27359 exclusion phecode
870.4 Open wound of nose and sinus Injuries & Poisonings 0.98 0.851 – 1.13 0.775 205 2060 exclusion phecode
870.6 Open wound of neck Injuries & Poisonings 0.933 0.728 – 1.2 0.583 62 648 exclusion phecode
871 Open wounds of extremities Injuries & Poisonings 1.05 1.01 – 1.08 0.00663 3818 38378 exclusion phecode
871.1 Open wound of hand except finger(s) Injuries & Poisonings 1.4 1.03 – 1.89 0.0302 48 492 exclusion phecode
871.2 Open wound of finger(s) Injuries & Poisonings 1.12 0.901 – 1.4 0.304 85 831 exclusion phecode
871.3 Open wound of foot except toe(s) alone Injuries & Poisonings 1.02 0.869 – 1.2 0.793 152 1697 exclusion phecode
872 Traumatic amputation Injuries & Poisonings 1.05 0.952 – 1.16 0.333 445 4452 exclusion phecode
873 Broken tooth Injuries & Poisonings 1.03 0.898 – 1.19 0.645 206 2153 exclusion phecode
874 Complication of amputation stump Injuries & Poisonings 1.15 0.956 – 1.39 0.135 118 1601 exclusion phecode
905
Late effects of musculoskeletal and connective
Late effects of musculoskeletal and connective tissue injuries
 Injuries & Poisonings 1.11 0.94 – 1.31 0.219 147 1473 exclusion phecode
907 Injuries to the nervous system Injuries & Poisonings 1.1 1.04 – 1.17 0.000859 1248 12415 exclusion phecode
915 Superficial injury without mention of infection Injuries & Poisonings 1.07 1.04 – 1.11 5.31e-05 3823 40191 exclusion phecode
916 Contusion Injuries & Poisonings 1.06 1 – 1.12 0.0398 1326 13662 exclusion phecode
930 Allergic reaction to food Injuries & Poisonings 1.03 0.874 – 1.2 0.758 166 1721 exclusion phecode
938 Dermatitis due to solar radiation Injuries & Poisonings 1 0.901 – 1.12 0.957 363 3639 exclusion phecode
938.2 Chronic dermatitis due to solar radiation Injuries & Poisonings 0.969 0.847 – 1.11 0.65 236 2354 exclusion phecode
939
Atopic/contact dermatitis due to other or
Atopic/contact dermatitis due to other or unspecified
 Dermatologic 1.05 0.999 – 1.1 0.0548 1938 19711 exclusion phecode
941 Adverse reaction to serum or vaccine Injuries & Poisonings 0.977 0.846 – 1.13 0.754 204 2116 exclusion phecode
942 Infusion and transfusion reaction Injuries & Poisonings 1.19 0.972 – 1.47 0.0915 98 986 exclusion phecode
946 Anaphylactic shock NOS Injuries & Poisonings 1.13 1.03 – 1.24 0.00953 487 5239 exclusion phecode
947 Urticaria Injuries & Poisonings 1.18 1.05 – 1.31 0.00369 348 3538 exclusion phecode
949 Allergies, other Injuries & Poisonings 1.1 0.992 – 1.22 0.0704 367 3816 exclusion phecode
952
Spinal cord injury without evidence of spinal
Spinal cord injury without evidence of spinal bone injury
 Injuries & Poisonings 1.05 0.941 – 1.16 0.402 386 3967 exclusion phecode
957 Injury to other and unspecified nerves Injuries & Poisonings 1.33 1.17 – 1.52 2.11e-05 248 2544 exclusion phecode
958
Certain early complications of trauma or
Certain early complications of trauma or procedure
 Injuries & Poisonings 1.07 0.972 – 1.18 0.166 447 4626 exclusion phecode
958.1 Postoperative shock Injuries & Poisonings 1.31 0.96 – 1.78 0.0897 43 509 exclusion phecode
958.2 Traumatic and surgical subcutaneous emphysema Injuries & Poisonings 0.894 0.708 – 1.13 0.346 70 685 exclusion phecode
960 Poisoning by antibiotics Injuries & Poisonings 1.08 1.07 – 1.1 5.64e-23 16634 172453 exclusion phecode
960.2 Allergy/adverse effect of penicillin Injuries & Poisonings 1.08 1.06 – 1.1 4.38e-20 14535 150937 exclusion phecode
961 Poisoning by other anti-infectives Injuries & Poisonings 1.09 0.981 – 1.21 0.11 380 3984 exclusion phecode
961.1 Poisoning/allergy of sulfonamides Injuries & Poisonings 1.06 0.989 – 1.14 0.0992 806 8332 exclusion phecode
962 Poisoning by hormones and synthetic substitutes Injuries & Poisonings 1.24 1.11 – 1.39 0.000253 315 3517 exclusion phecode
962.3
Hormones and synthetic substitutes causing
Hormones and synthetic substitutes causing adverse effects in therapeutic use
 Injuries & Poisonings 1.27 1.13 – 1.42 8.04e-05 307 3449 exclusion phecode
963 Poisoning by primarily systemic agents Injuries & Poisonings 1.2 1.04 – 1.38 0.0108 210 2118 exclusion phecode
964
Poisoning by agents primarily affecting blood
Poisoning by agents primarily affecting blood constituents
 Injuries & Poisonings 1.01 0.887 – 1.16 0.857 240 2617 exclusion phecode
964.1 Anticoagulants causing adverse effects Injuries & Poisonings 0.995 0.869 – 1.14 0.936 234 2561 exclusion phecode
965
Poisoning by analgesics, antipyretics, and
Poisoning by analgesics, antipyretics, and antirheumatics
 Injuries & Poisonings 1.13 1.09 – 1.16 7.41e-17 5530 57958 exclusion phecode
965.1
Opiates and related narcotics causing adverse
Opiates and related narcotics causing adverse effects in therapeutic use
 Injuries & Poisonings 1.09 1.03 – 1.17 0.0052 1038 10963 exclusion phecode
965.2
Antirheumatics causing adverse effects in
Antirheumatics causing adverse effects in therapeutic use
 Injuries & Poisonings 1.16 1.06 – 1.28 0.00216 433 4576 exclusion phecode
965.3
Salicylates causing adverse effects in
Salicylates causing adverse effects in therapeutic use
 Injuries & Poisonings 1.2 1.08 – 1.34 0.00104 357 3825 exclusion phecode
966
Poisoning by anticonvulsants and
Poisoning by anticonvulsants and anti-Parkinsonism drugs
 Injuries & Poisonings 1.13 1.03 – 1.25 0.0102 467 4894 exclusion phecode
967
Adverse effects of sedatives or other central
Adverse effects of sedatives or other central nervous system depressants and anesthetics
 Injuries & Poisonings 1.16 1.06 – 1.27 0.00106 542 5559 exclusion phecode
969 Poisoning by psychotropic agents Injuries & Poisonings 1.15 1.1 – 1.21 1.91e-08 1767 18683 exclusion phecode
971
Poisoning by drugs primarily affecting the
Poisoning by drugs primarily affecting the autonomic nervous system
 Injuries & Poisonings 1.13 0.966 – 1.32 0.127 168 1828 exclusion phecode
972
Poisoning by agents primarily affecting the
Poisoning by agents primarily affecting the cardiovascular system
 Injuries & Poisonings 1.24 1.08 – 1.42 0.00168 227 2590 exclusion phecode
972.6 Antihypertensive agents causing adverse effects Injuries & Poisonings 1.15 0.902 – 1.47 0.259 70 809 exclusion phecode
973
Poisoning by agents primarily affecting the
Poisoning by agents primarily affecting the gastrointestinal system
 Injuries & Poisonings 1.15 0.932 – 1.41 0.195 96 1021 exclusion phecode
974
Poisoning by water, mineral, and uric acid
Poisoning by water, mineral, and uric acid metabolism drugs
 Injuries & Poisonings 1.37 1.1 – 1.71 0.00556 83 947 exclusion phecode
975
Poisoning by agents primarily acting on the
Poisoning by agents primarily acting on the smooth and skeletal muscles and respiratory system
 Injuries & Poisonings 1.2 0.921 – 1.56 0.178 58 611 exclusion phecode
976
Poisoning by agents primarily affecting skin &
Poisoning by agents primarily affecting skin & mucous membrane, ophthalmological, otorhinolaryngological, & dental drugs
 Injuries & Poisonings 1.26 0.957 – 1.66 0.099 52 555 exclusion phecode
977 Personal history of allergy to medicinal agents Injuries & Poisonings 1.1 0.956 – 1.27 0.182 215 2208 exclusion phecode
979 Adverse drug events and drug allergies Injuries & Poisonings 1.14 1.05 – 1.24 0.00181 636 6637 exclusion phecode
981
Toxic effect of (non-ethyl) alcohol and
Toxic effect of (non-ethyl) alcohol and petroleum and other solvents
 Injuries & Poisonings 1.06 0.909 – 1.25 0.439 182 1903 exclusion phecode
986 Toxic effect of carbon monoxide Injuries & Poisonings 1.11 0.851 – 1.45 0.441 58 584 exclusion phecode
987 Toxic effect of other gases, fumes, or vapors Injuries & Poisonings 1.38 1.11 – 1.72 0.00354 93 988 exclusion phecode
988 Toxic effect of noxious substances eaten as food Injuries & Poisonings 0.957 0.784 – 1.17 0.665 102 1060 exclusion phecode
989
Toxic effect of other substances, chiefly
Toxic effect of other substances, chiefly nonmedicinal as to source
 Injuries & Poisonings 0.853 0.686 – 1.06 0.149 86 840 exclusion phecode
990 Effects radiation NOS Injuries & Poisonings 1.05 1.01 – 1.09 0.0127 2856 29168 exclusion phecode
994 Sepsis and SIRS Injuries & Poisonings 1.05 1.01 – 1.09 0.0179 2636 28313 exclusion phecode
994.2 Sepsis Injuries & Poisonings 1.05 1.01 – 1.09 0.0179 2636 28313 exclusion phecode
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