Departments of Anesthesiology and Biostatistics | University of Michigan

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Scores Type 2 diabetes UK Biobank (UKB) PheWAS analysis

Type 2 diabetes — UK Biobank (UKB) PRS PheWAS

PRS model
PRS ID exprsweb-t2d-metaanalysis-diagram-lassosum-ukb-20211120Legacy LASSOSUMlassosumLarge GWAS

Evaluation cohort: UK Biobank (UKB).

This page pairs the PheWAS plot with the full sortable table for the all-subject and exclusion scans.

Read the all-subject and exclusion scans separately. The combined view is only a browsing aid, and the selected-phecode panel below is only meaningful when the same phecode exists in both scans.

ExPRS exclusion definition

Exclusion cohort: individuals without Type 2 diabetes.

For this ExPRS, the exclusion sensitivity scan removes individuals with the exposure itself before rerunning the PheWAS. This is an exposure-based sensitivity analysis rather than a diagnosis-based exclusion.

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Signal overview

The plot gives a quick view of the currently visible associations. Click a point to pin its details, inspect that phecode across scans when both rows exist, or open the matching phecode detail page.

346 rows visible 17 categories
Phecode Description Category OR 95% CI P value Cases Controls Analysis Link
008 Intestinal infection Infectious Diseases 1.04 1.02 – 1.07 9.44e-05 8842 88430 all phecode
008.5 Bacterial enteritis Infectious Diseases 1.07 1.03 – 1.11 0.000656 2718 27172 all phecode
008.52 Intestinal infection due to C. difficile Infectious Diseases 1.04 0.96 – 1.13 0.338 653 6533 all phecode
008.6 Viral Enteritis Infectious Diseases 1.04 0.971 – 1.12 0.249 862 8622 all phecode
008.7 Intestinal infection due to protozoa Infectious Diseases 1.38 1.04 – 1.81 0.0234 55 550 all phecode
010 Tuberculosis Infectious Diseases 0.998 0.852 – 1.17 0.982 166 1659 all phecode
038 Septicemia Infectious Diseases 1.07 1.04 – 1.11 1.84e-05 4175 41776 all phecode
038.1 Gram negative septicemia Infectious Diseases 1.14 1.06 – 1.22 0.000383 850 8501 all phecode
038.2 Gram positive septicemia Infectious Diseases 1.06 0.969 – 1.17 0.194 494 4978 all phecode
041 Bacterial infection NOS Infectious Diseases 1.04 1.02 – 1.06 3.88e-05 12017 120377 all phecode
041.1 Staphylococcus infections Infectious Diseases 1.05 1.02 – 1.09 0.0053 3128 31348 all phecode
041.2 Streptococcus infection Infectious Diseases 1.05 1 – 1.11 0.0454 1641 16433 all phecode
041.4 E. coli Infectious Diseases 1.01 0.968 – 1.05 0.749 2730 27319 all phecode
053 Herpes zoster Infectious Diseases 1.07 0.964 – 1.18 0.215 411 4137 all phecode
053.1 Herpes zoster with nervous system complications Infectious Diseases 0.98 0.792 – 1.21 0.853 95 949 all phecode
054 Herpes simplex Infectious Diseases 0.957 0.83 – 1.1 0.55 211 2107 all phecode
070 Viral hepatitis Infectious Diseases 1.01 0.926 – 1.1 0.86 590 5916 all phecode
070.1 Viral hepatitis A Infectious Diseases 1 0.791 – 1.27 0.977 69 690 all phecode
070.2 Viral hepatitis B Infectious Diseases 1 0.841 – 1.2 0.972 132 1330 all phecode
070.3 Viral hepatitis C Infectious Diseases 0.932 0.82 – 1.06 0.283 255 2568 all phecode
070.4 Chronic hepatitis Infectious Diseases 1.01 0.889 – 1.14 0.903 276 2767 all phecode
070.9 Hepatitis NOS Infectious Diseases 1.12 1.01 – 1.23 0.026 428 4287 all phecode
071 Human immunodeficiency virus [HIV] disease Infectious Diseases 0.989 0.835 – 1.17 0.896 147 1467 all phecode
071.1 HIV infection, symptomatic Infectious Diseases 1.03 0.855 – 1.25 0.741 117 1168 all phecode
078 Viral warts & HPV Infectious Diseases 1.08 1.01 – 1.15 0.0242 1004 10036 all phecode
079 Viral infection Infectious Diseases 1.02 0.98 – 1.06 0.353 2769 27694 all phecode
079.1 Varicella infection Infectious Diseases 1.02 0.8 – 1.31 0.856 64 640 all phecode
080 Postoperative infection Infectious Diseases 1.05 1.02 – 1.08 0.00201 4473 44775 all phecode
081
Infection/inflammation of internal prosthetic
Infection/inflammation of internal prosthetic device; implant; and graft
 Infectious Diseases 1.04 0.996 – 1.08 0.08 2477 24765 all phecode
090
Sexually transmitted infections (not HIV or
Sexually transmitted infections (not HIV or hepatitis)
 Infectious Diseases 1.1 0.867 – 1.4 0.428 71 709 all phecode
1000 Burns Injuries & Poisonings 0.979 0.898 – 1.07 0.635 578 5796 all phecode
1001 Foreign body injury Injuries & Poisonings 0.978 0.922 – 1.04 0.459 1199 12007 all phecode
1002
Symptoms concerning nutrition, metabolism, and
Symptoms concerning nutrition, metabolism, and development
 Injuries & Poisonings 0.989 0.962 – 1.02 0.44 5480 54819 all phecode
1004
Other signs and symptoms involving emotional
Other signs and symptoms involving emotional state
 Injuries & Poisonings 0.981 0.873 – 1.1 0.743 300 2997 all phecode
1005 Other symptoms Injuries & Poisonings 1 0.95 – 1.06 0.922 1444 14422 all phecode
1006 Crushing injury Injuries & Poisonings 0.871 0.765 – 0.992 0.0378 256 2558 all phecode
1007 Injury to blood vessels Injuries & Poisonings 1 0.882 – 1.14 0.957 256 2559 all phecode
1008 Crushing or internal injury to organs Injuries & Poisonings 0.996 0.934 – 1.06 0.914 1013 10132 all phecode
1009 Injury, NOS Injuries & Poisonings 0.999 0.977 – 1.02 0.918 8482 84911 all phecode
1010 Other tests Injuries & Poisonings 1.04 1.01 – 1.07 0.00533 5945 59512 all phecode
1011 Complications of surgical and medical procedures Injuries & Poisonings 1.03 1.01 – 1.05 0.00594 9152 91588 all phecode
1012 Late effect Injuries & Poisonings 1.06 0.868 – 1.29 0.573 105 1057 all phecode
1013 Asphyxia and hypoxemia Injuries & Poisonings 1 0.894 – 1.12 0.97 316 3168 all phecode
1014 Effects of heat, cold and air pressure Injuries & Poisonings 0.944 0.737 – 1.21 0.649 66 659 all phecode
1015 Effects of other external causes Injuries & Poisonings 1.05 1.02 – 1.09 0.00117 4226 42294 all phecode
1019
Other ill-defined and unknown causes of
Other ill-defined and unknown causes of morbidity and mortality
 Injuries & Poisonings 1.03 1.01 – 1.04 0.000966 15895 159019 all phecode
110 Dermatophytosis / Dermatomycosis Infectious Diseases 1.09 0.965 – 1.24 0.164 279 2810 all phecode
110.1 Dermatophytosis Infectious Diseases 1.09 0.961 – 1.23 0.184 273 2750 all phecode
110.11 Dermatophytosis of nail Infectious Diseases 1.05 0.826 – 1.32 0.713 74 756 all phecode
110.12 Althete's foot Infectious Diseases 1.04 0.877 – 1.23 0.671 141 1410 all phecode
112 Candidiasis Infectious Diseases 1.04 0.997 – 1.09 0.0706 2126 21275 all phecode
117 Mycoses Infectious Diseases 1.02 0.898 – 1.15 0.793 272 2719 all phecode
117.4 Aspergillosis Infectious Diseases 0.899 0.764 – 1.06 0.196 165 1650 all phecode
130 Spirochetal infection Infectious Diseases 0.862 0.686 – 1.08 0.201 80 800 all phecode
133 Arthropod-borne diseases Infectious Diseases 0.898 0.701 – 1.15 0.394 69 689 all phecode
134 Helminthiases Infectious Diseases 0.882 0.736 – 1.06 0.172 127 1267 all phecode
134.1 Intestinal helminthiases Infectious Diseases 0.893 0.734 – 1.09 0.256 106 1058 all phecode
136 Other infectious and parasitic diseases Infectious Diseases 1.06 0.917 – 1.23 0.428 205 2050 all phecode
145 Cancer of mouth Neoplasms 1.02 0.939 – 1.11 0.658 642 6415 all phecode
145.2 Cancer of tongue Neoplasms 0.995 0.884 – 1.12 0.938 310 3096 all phecode
145.3 Cancer of major salivary glands Neoplasms 1.07 0.882 – 1.3 0.497 105 1049 all phecode
145.5 Cancer of the mouth floor Neoplasms 1.03 0.775 – 1.38 0.823 54 539 all phecode
149 Cancer of larynx, pharynx, nasal cavities Neoplasms 1.05 0.964 – 1.13 0.283 635 6342 all phecode
149.1 Cancer of oropharynx Neoplasms 1 0.879 – 1.14 0.999 252 2517 all phecode
149.4 Cancer of larynx Neoplasms 1.11 0.977 – 1.26 0.11 265 2640 all phecode
149.9 Cancer of of nasal cavities Neoplasms 1 0.759 – 1.32 0.994 57 570 all phecode
150 Cancer of esophagus Neoplasms 1 0.929 – 1.08 0.99 762 7630 all phecode
151 Cancer of stomach Neoplasms 1.02 0.937 – 1.11 0.637 569 5696 all phecode
153 Colorectal cancer Neoplasms 0.996 0.966 – 1.03 0.775 4580 45799 all phecode
153.2 Colon cancer Neoplasms 0.991 0.955 – 1.03 0.622 3105 31046 all phecode
153.3
Malignant neoplasm of rectum, rectosigmoid
Malignant neoplasm of rectum, rectosigmoid junction, and anus
 Neoplasms 0.989 0.946 – 1.03 0.639 2164 21640 all phecode
155 Cancer of liver and intrahepatic bile duct Neoplasms 0.992 0.893 – 1.1 0.876 400 4008 all phecode
155.1 Malignant neoplasm of liver, primary Neoplasms 1.09 0.925 – 1.28 0.303 158 1580 all phecode
157 Pancreatic cancer Neoplasms 1.04 0.962 – 1.13 0.31 659 6582 all phecode
158
Neoplasm of unspecified nature of digestive
Neoplasm of unspecified nature of digestive system
 Neoplasms 0.976 0.916 – 1.04 0.448 1063 10635 all phecode
159
Malignant neoplasm of other and ill-defined
Malignant neoplasm of other and ill-defined sites within the digestive organs and peritoneum
 Neoplasms 0.987 0.96 – 1.01 0.362 5567 55694 all phecode
159.2
Malignant neoplasm of small intestine
Malignant neoplasm of small intestine, including duodenum
 Neoplasms 0.968 0.836 – 1.12 0.663 190 1900 all phecode
159.3
Malignant neoplasm of gallbladder and
Malignant neoplasm of gallbladder and extrahepatic bile ducts
 Neoplasms 1.03 0.892 – 1.18 0.706 205 2048 all phecode
159.4
Malignant neoplasm of retroperitoneum and
Malignant neoplasm of retroperitoneum and peritoneum
 Neoplasms 1.07 0.927 – 1.24 0.351 193 1925 all phecode
164 Cancer of intrathoracic organs Neoplasms 1.1 0.852 – 1.43 0.459 60 600 all phecode
165 Cancer within the respiratory system Neoplasms 1.03 0.991 – 1.07 0.132 2824 28235 all phecode
165.1 Cancer of bronchus; lung Neoplasms 1.02 0.976 – 1.06 0.387 2230 22307 all phecode
170 Cancer of bone and connective tissue Neoplasms 0.981 0.887 – 1.08 0.711 437 4364 all phecode
170.1 Bone cancer Neoplasms 1.15 0.953 – 1.38 0.147 131 1309 all phecode
170.2 Cancer of connective tissue Neoplasms 0.929 0.828 – 1.04 0.212 331 3303 all phecode
172 Skin cancer Neoplasms 0.99 0.973 – 1.01 0.268 13495 134987 all phecode
172.1 Melanomas of skin, dx or hx Neoplasms 0.993 0.955 – 1.03 0.732 2681 26792 all phecode
172.11 Melanomas of skin Neoplasms 0.993 0.955 – 1.03 0.742 2713 27112 all phecode
172.2 Other non-epithelial cancer of skin Neoplasms 0.989 0.97 – 1.01 0.284 11000 110056 all phecode
172.3 Carcinoma in situ of skin Neoplasms 0.984 0.908 – 1.07 0.692 666 6656 all phecode
173 Neoplasm of uncertain behavior of skin Neoplasms 1.07 0.924 – 1.25 0.352 181 1818 all phecode
174 Breast cancer Neoplasms 0.995 0.977 – 1.01 0.577 12686 126597 all phecode
174.1 Breast cancer [female] Neoplasms 0.997 0.979 – 1.02 0.755 12476 124506 all phecode
174.11 Malignant neoplasm of female breast Neoplasms 0.999 0.98 – 1.02 0.944 11757 117502 all phecode
174.3 Neoplasm of uncertain behavior of breast Neoplasms 1.13 0.928 – 1.38 0.222 115 1148 all phecode
175 Acquired absence of breast Neoplasms 0.968 0.928 – 1.01 0.138 2400 24010 all phecode
180 Cervical cancer and dysplasia Neoplasms 1 0.959 – 1.05 0.91 2174 21747 all phecode
180.1 Cervical cancer Neoplasms 1.02 0.901 – 1.16 0.73 272 2720 all phecode
180.3
Cervical intraepithelial neoplasia [CIN]
Cervical intraepithelial neoplasia [CIN] [Cervical dysplasia]
 Neoplasms 1.01 0.969 – 1.06 0.545 2078 20784 all phecode
182 Malignant neoplasm of uterus Neoplasms 1.01 0.954 – 1.07 0.729 1282 12836 all phecode
184 Cancer of other female genital organs Neoplasms 1.03 0.972 – 1.09 0.346 1378 13772 all phecode
184.1
Malignant neoplasm of ovary and other uterine
Malignant neoplasm of ovary and other uterine adnexa
 Neoplasms 1.03 0.966 – 1.1 0.346 967 9667 all phecode
184.11 Malignant neoplasm of ovary Neoplasms 1.05 0.979 – 1.12 0.178 939 9387 all phecode
184.2
Cancer of other female genital organs
Cancer of other female genital organs (excluding uterus and ovary)
 Neoplasms 0.989 0.879 – 1.11 0.859 305 3049 all phecode
185 Cancer of prostate Neoplasms 0.976 0.95 – 1 0.0745 5974 58812 all phecode
187 Cancer of other male genital organs Neoplasms 1.06 0.965 – 1.17 0.216 449 4485 all phecode
187.1
Malignant neoplasm of unspecified male genital
Malignant neoplasm of unspecified male genital organ
 Neoplasms 1.08 0.846 – 1.39 0.529 70 700 all phecode
187.2 Malignant neoplasm of testis Neoplasms 0.977 0.866 – 1.1 0.708 287 2868 all phecode
187.8
Neoplasm of uncertain behavior of male genital
Neoplasm of uncertain behavior of male genital organs
 Neoplasms 1.3 1.06 – 1.59 0.0121 110 1098 all phecode
189
Cancer of urinary organs (incl. kidney and
Cancer of urinary organs (incl. kidney and bladder)
 Neoplasms 1.04 1 – 1.07 0.0299 4160 41604 all phecode
189.1 Cancer of kidney and renal pelvis Neoplasms 1.08 1.01 – 1.15 0.0156 1073 10723 all phecode
189.11 Malignant neoplasm of kidney, except pelvis Neoplasms 1.1 1.03 – 1.17 0.00505 1033 10324 all phecode
189.12 Malignant neoplasm of renal pelvis Neoplasms 0.816 0.636 – 1.05 0.109 66 660 all phecode
189.2 Cancer of bladder Neoplasms 1.03 0.989 – 1.08 0.146 2409 24113 all phecode
189.21 Malignant neoplasm of bladder Neoplasms 1.04 0.991 – 1.08 0.123 2142 21447 all phecode
189.4 Malignant neoplasm of other urinary organs Neoplasms 0.97 0.811 – 1.16 0.735 144 1439 all phecode
190 Cancer of eye Neoplasms 0.973 0.831 – 1.14 0.734 176 1758 all phecode
191
Manlignant and unknown neoplasms of brain and
Manlignant and unknown neoplasms of brain and nervous system
 Neoplasms 0.964 0.891 – 1.04 0.353 689 6879 all phecode
191.1 Cancer of brain and nervous system Neoplasms 0.977 0.895 – 1.07 0.593 566 5650 all phecode
191.11 Cancer of brain Neoplasms 0.998 0.912 – 1.09 0.965 525 5240 all phecode
193 Thyroid cancer Neoplasms 1.06 0.95 – 1.18 0.297 346 3466 all phecode
194 Cancer of other endocrine glands Neoplasms 0.891 0.72 – 1.1 0.29 95 949 all phecode
195 Cancer, suspected or other Neoplasms 1 0.989 – 1.02 0.567 16967 165463 all phecode
195.1 Malignant neoplasm, other Neoplasms 1 0.985 – 1.02 0.886 16267 159497 all phecode
197 Chemotherapy Neoplasms 1.02 1.01 – 1.04 0.00103 21433 213213 all phecode
198 Secondary malignant neoplasm Neoplasms 1.01 0.985 – 1.03 0.597 9552 95503 all phecode
198.1 Secondary malignancy of lymph nodes Neoplasms 0.981 0.954 – 1.01 0.187 5368 53670 all phecode
198.2 Secondary malignancy of respiratory organs Neoplasms 1 0.957 – 1.04 0.998 2267 22670 all phecode
198.3
Secondary malignant neoplasm of digestive
Secondary malignant neoplasm of digestive systems
 Neoplasms 0.989 0.939 – 1.04 0.674 1549 15496 all phecode
198.4 Secondary malignant neoplasm of liver Neoplasms 0.995 0.956 – 1.04 0.803 2665 26648 all phecode
198.5 Secondary malignancy of brain/spine Neoplasms 0.985 0.917 – 1.06 0.684 848 8473 all phecode
198.6 Secondary malignancy of bone Neoplasms 1.01 0.965 – 1.05 0.707 2161 21600 all phecode
198.7 Secondary malignant neoplasm of skin Neoplasms 1.05 0.901 – 1.22 0.544 188 1890 all phecode
199 Neoplasm of uncertain behavior Neoplasms 1.04 0.985 – 1.1 0.155 1432 14313 all phecode
199.4 Neurofibromatosis Neoplasms 1.08 0.889 – 1.31 0.437 95 950 all phecode
200 Myeloproliferative disease Neoplasms 1.04 0.974 – 1.11 0.241 991 9911 all phecode
200.1 Polycythemia vera Neoplasms 1.01 0.914 – 1.13 0.785 387 3867 all phecode
201 Hodgkin's disease Neoplasms 0.896 0.786 – 1.02 0.0999 259 2598 all phecode
202 Cancer of other lymphoid, histiocytic tissue Neoplasms 1 0.958 – 1.04 0.983 2264 22709 all phecode
202.2 Non-Hodgkins lymphoma Neoplasms 0.987 0.94 – 1.04 0.596 1802 18073 all phecode
202.21 Nodular lymphoma Neoplasms 0.903 0.811 – 1.01 0.0644 363 3647 all phecode
202.24 Large cell lymphoma Neoplasms 1.03 0.944 – 1.12 0.528 581 5824 all phecode
204 Leukemia Neoplasms 1.07 1.01 – 1.12 0.0136 1660 16630 all phecode
204.1 Lymphoid leukemia Neoplasms 1.06 0.977 – 1.16 0.157 577 5784 all phecode
204.11 Lymphoid leukemia, acute Neoplasms 1.07 0.819 – 1.39 0.631 56 560 all phecode
204.12 Lymphoid leukemia, chronic Neoplasms 1.08 0.988 – 1.19 0.0881 507 5084 all phecode
204.2 Myeloid leukemia Neoplasms 1.03 0.937 – 1.13 0.545 462 4617 all phecode
204.21 Myeloid leukemia, acute Neoplasms 1.07 0.961 – 1.2 0.209 329 3287 all phecode
204.22 Myeloid leukemia, chronic Neoplasms 1.05 0.885 – 1.25 0.565 144 1440 all phecode
204.4 Multiple myeloma Neoplasms 1.07 0.981 – 1.17 0.127 555 5560 all phecode
208 Benign neoplasm of colon Neoplasms 1.02 1.01 – 1.04 0.00287 19856 191891 all phecode
210 Benign neoplasm of lip, oral cavity, and pharynx Neoplasms 1.06 0.993 – 1.13 0.0784 978 9781 all phecode
211
Benign neoplasm of other parts of digestive
Benign neoplasm of other parts of digestive system
 Neoplasms 1.02 0.99 – 1.05 0.194 5243 52452 all phecode
212
Benign neoplasm of respiratory and
Benign neoplasm of respiratory and intrathoracic organs
 Neoplasms 1.01 0.906 – 1.13 0.863 347 3466 all phecode
213 Benign neoplasm of bone and articular cartilage Neoplasms 0.992 0.884 – 1.11 0.895 318 3187 all phecode
214 Lipoma Neoplasms 1.04 1.02 – 1.07 0.00108 6231 62346 all phecode
214.1 Lipoma of skin and subcutaneous tissue Neoplasms 1.05 1.01 – 1.08 0.0035 4585 45872 all phecode
215
Other benign neoplasm of connective and other
Other benign neoplasm of connective and other soft tissue
 Neoplasms 1.04 0.976 – 1.1 0.238 1107 11061 all phecode
216 Benign neoplasm of skin Neoplasms 1 0.981 – 1.03 0.712 7664 76660 all phecode
217 Vascular hamartomas and non-neoplastic nevi Neoplasms 0.968 0.892 – 1.05 0.431 632 6313 all phecode
217.1 Nevus, non-neoplastic Neoplasms 0.971 0.893 – 1.06 0.496 595 5943 all phecode
218 Benign neoplasm of uterus Neoplasms 1.05 1.03 – 1.07 2.63e-06 10023 100200 all phecode
218.1 Uterine leiomyoma Neoplasms 1.05 1.03 – 1.07 6.08e-07 10241 102376 all phecode
218.2 Other benign neoplasm of uterus Neoplasms 1.06 0.949 – 1.18 0.319 355 3548 all phecode
220 Benign neoplasm of ovary Neoplasms 0.99 0.938 – 1.05 0.727 1445 14483 all phecode
221 Benign neoplasm of other female genital organs Neoplasms 0.998 0.868 – 1.15 0.983 220 2196 all phecode
222 Benign neoplasm of male genital organs Neoplasms 0.94 0.798 – 1.11 0.458 160 1600 all phecode
223
Benign neoplasm of kidney and other urinary
Benign neoplasm of kidney and other urinary organs
 Neoplasms 1.13 0.969 – 1.33 0.116 173 1729 all phecode
224 Benign neoplasm of eye Neoplasms 1.02 0.851 – 1.22 0.851 129 1299 all phecode
224.1 Benign neoplasm of eye, uveal Neoplasms 1.04 0.816 – 1.32 0.762 67 680 all phecode
225
Benign neoplasm of brain and other parts of
Benign neoplasm of brain and other parts of nervous system
 Neoplasms 0.959 0.892 – 1.03 0.254 816 8155 all phecode
225.1
Benign neoplasm of brain, cranial nerves
Benign neoplasm of brain, cranial nerves, meninges
 Neoplasms 0.941 0.874 – 1.01 0.111 775 7756 all phecode
225.2 Benign neoplasm of spinal cord, meninges Neoplasms 1.24 0.955 – 1.61 0.106 59 589 all phecode
226 Benign neoplasm of thyroid glands Neoplasms 0.959 0.845 – 1.09 0.509 266 2664 all phecode
227
Benign neoplasm of other endocrine glands and
Benign neoplasm of other endocrine glands and related structures
 Neoplasms 1.02 0.951 – 1.09 0.583 861 8635 all phecode
227.1 Benign neoplasm of adrenal gland Neoplasms 1.01 0.874 – 1.17 0.873 186 1857 all phecode
227.2 Benign neoplasm of parathyroid gland Neoplasms 1.01 0.91 – 1.13 0.818 371 3709 all phecode
227.3
Benign neoplasm of pituitary gland and
Benign neoplasm of pituitary gland and craniopharyngeal duct (pouch)
 Neoplasms 1.02 0.91 – 1.15 0.692 309 3114 all phecode
228 Hemangioma and lymphangioma, any site Neoplasms 0.995 0.945 – 1.05 0.85 1596 15966 all phecode
229 Benign neoplasm of unspecified sites Neoplasms 1.01 0.973 – 1.06 0.488 2397 23955 all phecode
240 Simple and unspecified goiter Endocrine/metabolic 1.05 0.965 – 1.14 0.265 600 6016 all phecode
241 Nontoxic nodular goiter Endocrine/metabolic 1 0.942 – 1.07 0.923 1107 11092 all phecode
241.1 Nontoxic uninodular goiter Endocrine/metabolic 1.03 0.936 – 1.13 0.546 471 4706 all phecode
241.2 Nontoxic multinodular goiter Endocrine/metabolic 0.963 0.89 – 1.04 0.355 676 6784 all phecode
242 Thyrotoxicosis with or without goiter Endocrine/metabolic 1.07 1.02 – 1.13 0.0045 1854 18531 all phecode
242.1 Graves' disease Endocrine/metabolic 1.08 0.982 – 1.19 0.114 456 4553 all phecode
242.2 Toxic multinodular goiter Endocrine/metabolic 1.09 0.877 – 1.35 0.436 91 910 all phecode
242.3 Exophthalmos Endocrine/metabolic 0.943 0.79 – 1.13 0.518 138 1379 all phecode
244 Hypothyroidism Endocrine/metabolic 1.03 1.01 – 1.05 0.00185 14590 145053 all phecode
244.1 Secondary hypothyroidism Endocrine/metabolic 1.03 0.971 – 1.1 0.301 1108 11079 all phecode
244.2 Acquired hypothyroidism Endocrine/metabolic 0.936 0.766 – 1.14 0.519 101 1010 all phecode
244.4 Hypothyroidism NOS Endocrine/metabolic 1.03 1.01 – 1.04 0.00306 13918 138926 all phecode
245 Thyroiditis Endocrine/metabolic 0.996 0.884 – 1.12 0.953 288 2877 all phecode
245.2 Chronic thyroiditis Endocrine/metabolic 1.08 0.942 – 1.24 0.269 218 2177 all phecode
245.21 Chronic lymphocytic thyroiditis Endocrine/metabolic 1.08 0.939 – 1.24 0.286 210 2097 all phecode
246 Other disorders of thyroid Endocrine/metabolic 0.996 0.899 – 1.1 0.942 397 3975 all phecode
250 Diabetes mellitus Endocrine/metabolic 1.57 1.54 – 1.59 7.91e-750 19787 186006 all phecode
250.1 Type 1 diabetes Endocrine/metabolic 1.44 1.38 – 1.49 2.59e-71 2758 27621 all phecode
250.11 Type 1 diabetes with ketoacidosis Endocrine/metabolic 1.11 0.97 – 1.27 0.129 239 2389 all phecode
250.12 Type 1 diabetes with renal manifestations Endocrine/metabolic 1.23 0.981 – 1.55 0.0719 76 770 all phecode
250.13 Type 1 diabetes with ophthalmic manifestations Endocrine/metabolic 1.35 1.22 – 1.48 1.73e-09 473 4744 all phecode
250.14 Type 1 diabetes with neurological manifestations Endocrine/metabolic 1.2 1.02 – 1.42 0.0255 160 1610 all phecode
250.2 Type 2 diabetes Endocrine/metabolic 1.61 1.58 – 1.63 1e-752 17831 170202 all phecode
250.21 Type 2 diabetes with ketoacidosis Endocrine/metabolic 1.35 1.1 – 1.64 0.00326 104 1050 all phecode
250.22 Type 2 diabetes with renal manifestations Endocrine/metabolic 1.77 1.53 – 2.05 3.29e-14 200 2018 all phecode
250.23 Type 2 diabetes with ophthalmic manifestations Endocrine/metabolic 1.9 1.77 – 2.03 6.3e-76 986 9907 all phecode
250.24 Type 2 diabetes with neurological manifestations Endocrine/metabolic 1.78 1.62 – 1.96 2.54e-33 503 5066 all phecode
250.4 Abnormal glucose Endocrine/metabolic 1.34 1.24 – 1.45 6.01e-13 680 6827 all phecode
250.41 Impaired fasting glucose Endocrine/metabolic 1.39 1.22 – 1.57 3.67e-07 265 2659 all phecode
250.42 Other abnormal glucose Endocrine/metabolic 1.31 1.19 – 1.45 1.52e-07 416 4178 all phecode
250.5 Glycosuria or Acetonuria Endocrine/metabolic 1.35 1.12 – 1.63 0.00175 131 1308 all phecode
250.6 Polyneuropathy in diabetes Endocrine/metabolic 1.76 1.57 – 1.96 7.49e-23 349 3495 all phecode
250.7 Diabetic retinopathy Endocrine/metabolic 1.6 1.51 – 1.69 4.49e-58 1329 13335 all phecode
251.1 Hypoglycemia Endocrine/metabolic 1.32 1.23 – 1.41 8.77e-16 932 9370 all phecode
252 Disorders of parathyroid gland Endocrine/metabolic 1.04 0.969 – 1.11 0.289 873 8719 all phecode
252.1 Hyperparathyroidism Endocrine/metabolic 1.03 0.958 – 1.11 0.408 781 7802 all phecode
252.2 Hypoparathyroidism Endocrine/metabolic 1.18 0.992 – 1.4 0.0616 142 1418 all phecode
253
Disorders of the pituitary gland and its
Disorders of the pituitary gland and its hypothalamic control
 Endocrine/metabolic 1.03 0.95 – 1.11 0.494 681 6821 all phecode
253.1 Pituitary hyperfunction Endocrine/metabolic 1.11 0.957 – 1.3 0.166 187 1867 all phecode
253.11 Acromegaly and gigantism Endocrine/metabolic 1.17 0.95 – 1.44 0.139 95 949 all phecode
253.2 Pituitary hypofunction Endocrine/metabolic 0.955 0.842 – 1.08 0.478 260 2618 all phecode
253.3 Diabetes insipidus Endocrine/metabolic 1.03 0.83 – 1.28 0.79 92 919 all phecode
253.7 Other disorders of neurohypophysis Endocrine/metabolic 1 0.848 – 1.18 0.996 158 1578 all phecode
255 Disorders of adrenal glands Endocrine/metabolic 1.08 0.992 – 1.17 0.0753 638 6374 all phecode
255.1 Adrenal hyperfunction Endocrine/metabolic 1.08 0.93 – 1.27 0.299 180 1797 all phecode
255.11 Cushing's syndrome Endocrine/metabolic 1.08 0.882 – 1.32 0.456 103 1029 all phecode
255.12 Hyperaldosteronism Endocrine/metabolic 1.18 0.934 – 1.49 0.167 76 759 all phecode
255.2 Adrenal hypofunction Endocrine/metabolic 1.01 0.904 – 1.12 0.891 362 3617 all phecode
255.21 Glucocorticoid deficiency Endocrine/metabolic 1.01 0.907 – 1.13 0.836 361 3607 all phecode
256 Ovarian dysfunction Endocrine/metabolic 1.15 1.01 – 1.31 0.041 240 2397 all phecode
256.4 Polycystic ovaries Endocrine/metabolic 1.17 1.01 – 1.34 0.0347 209 2088 all phecode
257 Testicular dysfunction Endocrine/metabolic 0.956 0.81 – 1.13 0.59 160 1619 all phecode
257.1 Testicular hypofunction Endocrine/metabolic 1 0.846 – 1.19 0.982 152 1539 all phecode
258 Iatrogenic endocrine disorders Endocrine/metabolic 1.16 0.946 – 1.42 0.155 102 1020 all phecode
259 Other endocrine disorders Endocrine/metabolic 0.994 0.837 – 1.18 0.949 149 1498 all phecode
260 Protein-calorie malnutrition Endocrine/metabolic 1.01 0.873 – 1.16 0.927 202 2018 all phecode
260.1 Cachexia Endocrine/metabolic 0.973 0.734 – 1.29 0.846 51 510 all phecode
260.6 Anorexia Endocrine/metabolic 0.971 0.905 – 1.04 0.42 830 8317 all phecode
261 Vitamin deficiency Endocrine/metabolic 1.03 0.971 – 1.09 0.329 1199 11974 all phecode
261.2 Vitamin B-complex deficiencies Endocrine/metabolic 0.998 0.926 – 1.08 0.969 755 7541 all phecode
261.4 Vitamin D deficiency Endocrine/metabolic 1.07 0.974 – 1.18 0.151 447 4462 all phecode
261.41 Rickets or osteomalacia Endocrine/metabolic 1.06 0.85 – 1.33 0.584 77 769 all phecode
262 Mineral deficiency NEC Endocrine/metabolic 0.994 0.87 – 1.14 0.929 241 2407 all phecode
269 Proteinuria Endocrine/metabolic 1.17 1.05 – 1.31 0.00595 338 3378 all phecode
270
Disorders of protein plasma/amino-acid
Disorders of protein plasma/amino-acid transport and metabolism
 Endocrine/metabolic 1.02 0.904 – 1.14 0.78 303 3028 all phecode
270.3 Disorders of plasma protein metabolism Endocrine/metabolic 0.994 0.877 – 1.13 0.927 261 2608 all phecode
270.32 Paraproteinemia Endocrine/metabolic 1.01 0.875 – 1.17 0.864 191 1910 all phecode
270.33 Amyloidosis Endocrine/metabolic 1.1 0.911 – 1.32 0.33 113 1129 all phecode
270.35 Macroglobulinemia Endocrine/metabolic 0.922 0.722 – 1.18 0.515 69 689 all phecode
271
Disorders of carbohydrate transport and
Disorders of carbohydrate transport and metabolism
 Endocrine/metabolic 1.35 1.15 – 1.59 0.000283 160 1600 all phecode
271.3
Intestinal disaccharidase deficiencies and
Intestinal disaccharidase deficiencies and disaccharide malabsorption
 Endocrine/metabolic 1.31 1.1 – 1.55 0.00223 139 1391 all phecode
272 Disorders of lipoid metabolism Endocrine/metabolic 1.11 1.1 – 1.12 1.75e-69 34835 235433 all phecode
272.1 Hyperlipidemia Endocrine/metabolic 1.11 1.1 – 1.12 3.25e-70 34764 235203 all phecode
272.11 Hypercholesterolemia Endocrine/metabolic 1.11 1.1 – 1.12 2.15e-66 32324 228083 all phecode
272.12 Hyperglyceridemia Endocrine/metabolic 1.05 0.811 – 1.36 0.708 58 580 all phecode
272.13 Mixed hyperlipidemia Endocrine/metabolic 1.17 1 – 1.37 0.0496 164 1637 all phecode
272.9 Unspecified disorder of lipoid metabolism Endocrine/metabolic 1.23 1.07 – 1.43 0.00449 211 2109 all phecode
274 Gout and other crystal arthropathies Endocrine/metabolic 1.09 1.05 – 1.12 1.4e-06 3724 37231 all phecode
274.1 Gout Endocrine/metabolic 1.07 1.04 – 1.11 0.00012 3171 31705 all phecode
274.11 Gouty arthropathy Endocrine/metabolic 1.09 0.902 – 1.32 0.373 112 1119 all phecode
274.2 Crystal arthropathies Endocrine/metabolic 1.17 1.08 – 1.27 0.000246 613 6124 all phecode
274.21 Chondrocalcinosis Endocrine/metabolic 1.17 1.07 – 1.28 0.000409 558 5576 all phecode
275 Disorders of mineral metabolism Endocrine/metabolic 1.02 0.974 – 1.07 0.423 2107 21070 all phecode
275.1 Disorders of iron metabolism Hematopoietic 0.925 0.854 – 1 0.0569 653 6535 all phecode
275.3 Disorders of magnesium metabolism Endocrine/metabolic 1.12 1 – 1.25 0.0415 375 3745 all phecode
275.5 Disorders of calcium/phosphorus metabolism Endocrine/metabolic 1.05 0.988 – 1.11 0.116 1202 12019 all phecode
275.53 Disorders of phosphorus metabolism Endocrine/metabolic 1.09 0.934 – 1.28 0.269 171 1717 all phecode
276
Disorders of fluid, electrolyte, and acid-base
Disorders of fluid, electrolyte, and acid-base balance
 Endocrine/metabolic 1.05 1.03 – 1.08 5.55e-05 7284 72932 all phecode
276.1 Electrolyte imbalance Endocrine/metabolic 1.05 1.02 – 1.09 0.00117 4086 40930 all phecode
276.11 Hyperosmolality and/or hypernatremia Endocrine/metabolic 1.08 0.947 – 1.23 0.249 239 2409 all phecode
276.12 Hyposmolality and/or hyponatremia Endocrine/metabolic 1.02 0.969 – 1.07 0.488 1818 18200 all phecode
276.13 Hyperpotassemia Endocrine/metabolic 1.12 1.05 – 1.2 0.000822 969 9728 all phecode
276.14 Hypopotassemia Endocrine/metabolic 1.09 1.03 – 1.15 0.00175 1424 14235 all phecode
276.4 Acid-base balance disorder Endocrine/metabolic 1.12 1.05 – 1.19 0.000263 1161 11629 all phecode
276.41 Acidosis Endocrine/metabolic 1.11 1.04 – 1.18 0.00127 1056 10577 all phecode
276.42 Alkalosis Endocrine/metabolic 1.1 0.906 – 1.34 0.336 113 1129 all phecode
276.5 Hypovolemia Endocrine/metabolic 1.03 0.994 – 1.07 0.101 2827 28265 all phecode
276.6 Fluid overload Endocrine/metabolic 1.06 0.957 – 1.16 0.28 451 4535 all phecode
276.8 Polydipsia Endocrine/metabolic 1.04 0.873 – 1.24 0.65 128 1278 all phecode
277 Other disorders of metabolism Endocrine/metabolic 0.992 0.925 – 1.06 0.813 899 8977 all phecode
277.4 Disorders of bilirubin excretion Endocrine/metabolic 1.02 0.914 – 1.13 0.75 362 3613 all phecode
277.5 Other disorders of lipoid metabolism Endocrine/metabolic 1.18 1.03 – 1.35 0.0199 230 2298 all phecode
277.51 Lipoprotein disorders Endocrine/metabolic 1.03 0.774 – 1.37 0.85 52 520 all phecode
278 Overweight, obesity and other hyperalimentation Endocrine/metabolic 1.13 1.11 – 1.15 9.25e-33 10804 108289 all phecode
278.1 Obesity Endocrine/metabolic 1.13 1.1 – 1.15 1.41e-31 10642 106670 all phecode
278.3 Localized adiposity Endocrine/metabolic 1.21 0.968 – 1.51 0.0948 84 838 all phecode
278.4 Abnormal weight gain Endocrine/metabolic 1.17 0.91 – 1.49 0.226 66 660 all phecode
279 Disorders involving the immune mechanism Endocrine/metabolic 0.974 0.856 – 1.11 0.686 250 2510 all phecode
279.1 Immunity deficiency Endocrine/metabolic 0.981 0.851 – 1.13 0.793 209 2100 all phecode
279.11 Deficiency of humoral immunity Endocrine/metabolic 0.896 0.75 – 1.07 0.23 138 1390 all phecode
279.7 Other immunological findings Endocrine/metabolic 0.978 0.86 – 1.11 0.73 248 2478 all phecode
280 Iron deficiency anemias Hematopoietic 1.06 1.04 – 1.09 6.21e-07 7610 76168 all phecode
280.1
Iron deficiency anemias, unspecified or not due
Iron deficiency anemias, unspecified or not due to blood loss
 Hematopoietic 1.07 1.04 – 1.09 1.86e-07 7311 73153 all phecode
280.2
Iron deficiency anemia secondary to blood loss
Iron deficiency anemia secondary to blood loss (chronic)
 Hematopoietic 1.02 0.93 – 1.13 0.645 452 4541 all phecode
281 Other deficiency anemia Hematopoietic 1.07 1 – 1.14 0.0342 1112 11126 all phecode
281.1 Megaloblastic anemia Hematopoietic 1.07 1.01 – 1.14 0.0335 1066 10669 all phecode
281.11 Pernicious anemia Hematopoietic 1.09 1.01 – 1.17 0.0304 750 7514 all phecode
281.12 Other vitamin B12 deficiency anemia Hematopoietic 1.19 1.02 – 1.39 0.0256 177 1769 all phecode
281.13 Folate-deficiency anemia Hematopoietic 0.906 0.777 – 1.06 0.206 183 1836 all phecode
281.9 Deficiency anemias Hematopoietic 1.13 0.846 – 1.5 0.415 54 538 all phecode
282 Hereditary hemolytic anemias Hematopoietic 1.19 1.01 – 1.4 0.0364 150 1499 all phecode
282.8 Other hemoglobinopathies Hematopoietic 1.19 0.909 – 1.56 0.203 56 560 all phecode
282.9 Other hereditary hemolytic anemias Hematopoietic 1.22 0.977 – 1.52 0.0796 85 849 all phecode
283 Acquired hemolytic anemias Hematopoietic 1.02 0.86 – 1.22 0.796 135 1377 all phecode
283.1 Autoimmune hemolytic anemias Hematopoietic 1.07 0.876 – 1.31 0.501 103 1059 all phecode
284 Aplastic anemia Hematopoietic 1.04 0.941 – 1.15 0.458 435 4357 all phecode
285 Other anemias Hematopoietic 1.04 1.02 – 1.06 7.73e-05 12104 121094 all phecode
285.1 Acute posthemorrhagic anemia Hematopoietic 1.02 0.901 – 1.16 0.75 271 2707 all phecode
285.2 Anemia of chronic disease Hematopoietic 0.998 0.923 – 1.08 0.969 697 6980 all phecode
285.22 Anemia in neoplastic disease Hematopoietic 0.928 0.838 – 1.03 0.151 414 4147 all phecode
286 Coagulation defects Hematopoietic 1.01 0.942 – 1.08 0.814 921 9218 all phecode
286.1 Congenital coagulation defects Hematopoietic 0.974 0.884 – 1.07 0.583 459 4594 all phecode
286.11 Von willebrand's disease Hematopoietic 0.941 0.762 – 1.16 0.57 96 959 all phecode
286.12
Congenital deficiency of other clotting factors
Congenital deficiency of other clotting factors (including factor VII)
 Hematopoietic 1.01 0.892 – 1.13 0.93 294 2944 all phecode
286.13 Congenital factor VIII disorder Hematopoietic 0.975 0.754 – 1.26 0.844 63 630 all phecode
286.5
Hemorrhagic disorder due to intrinsic
Hemorrhagic disorder due to intrinsic circulating anticoagulants
 Hematopoietic 1.06 0.855 – 1.33 0.576 86 860 all phecode
286.7 Other and unspecified coagulation defects Hematopoietic 0.988 0.889 – 1.1 0.825 386 3867 all phecode
287 Purpura and other hemorrhagic conditions Hematopoietic 1.03 0.975 – 1.08 0.325 1652 16532 all phecode
287.1 Spontaneous ecchymoses Hematopoietic 1.04 0.87 – 1.24 0.668 129 1290 all phecode
287.2 Allergic purpura Hematopoietic 1.07 0.807 – 1.41 0.647 51 510 all phecode
287.3 Thrombocytopenia Hematopoietic 1.03 0.974 – 1.08 0.337 1553 15543 all phecode
287.31 Primary thrombocytopenia Hematopoietic 1.11 1.01 – 1.23 0.0367 419 4195 all phecode
287.32 Secondary thrombocytopenia Hematopoietic 0.878 0.687 – 1.12 0.297 75 749 all phecode
288 Diseases of white blood cells Hematopoietic 1.02 0.987 – 1.05 0.245 3765 37672 all phecode
288.1 Decreased white blood cell count Hematopoietic 1.01 0.978 – 1.05 0.458 3168 31704 all phecode
288.11 Neutropenia Hematopoietic 1.01 0.977 – 1.05 0.473 3176 31784 all phecode
288.3 Eosinophilia Hematopoietic 0.999 0.793 – 1.26 0.991 71 709 all phecode
289 Other diseases of blood and blood-forming organs Hematopoietic 1.03 0.963 – 1.11 0.36 862 8625 all phecode
289.3
Personal history of diseases of blood and
Personal history of diseases of blood and blood-forming organs
 Hematopoietic 1.09 0.968 – 1.24 0.151 290 2897 all phecode
289.4 Lymphadenitis Hematopoietic 1 0.962 – 1.04 0.931 2602 26061 all phecode
289.5 Diseases of spleen Hematopoietic 1 0.916 – 1.1 0.939 516 5153 all phecode
289.8 Polycythemia, secondary Hematopoietic 1.02 0.91 – 1.15 0.688 292 2917 all phecode
289.9 Abnormality of red blood cells Hematopoietic 0.888 0.713 – 1.11 0.287 90 900 all phecode
290
Delirium dementia and amnestic and other
Delirium dementia and amnestic and other cognitive disorders
 Mental Disorders 0.97 0.926 – 1.02 0.2 1929 19281 all phecode
290.1 Dementias Mental Disorders 0.954 0.894 – 1.02 0.153 1004 10032 all phecode
290.11 Alzheimer's disease Mental Disorders 0.922 0.834 – 1.02 0.11 431 4307 all phecode
290.16 Vascular dementia Mental Disorders 0.96 0.831 – 1.11 0.579 201 2008 all phecode
290.2 Delirium due to conditions classified elsewhere Mental Disorders 0.994 0.917 – 1.08 0.892 650 6501 all phecode
290.3
Other persistent mental disorders due to
Other persistent mental disorders due to conditions classified elsewhere
 Mental Disorders 1.21 0.956 – 1.54 0.111 70 709 all phecode
291
Other specified nonpsychotic and/or transient
Other specified nonpsychotic and/or transient mental disorders
 Mental Disorders 1.06 0.988 – 1.14 0.101 836 8385 all phecode
291.1
Transient mental disorders due to conditions
Transient mental disorders due to conditions classified elsewhere
 Mental Disorders 1.03 0.861 – 1.23 0.754 132 1320 all phecode
291.4
Specific nonpsychotic mental disorders due to
Specific nonpsychotic mental disorders due to brain damage
 Mental Disorders 1.01 0.898 – 1.14 0.856 286 2867 all phecode
291.8 Alteration of consciousness Mental Disorders 1.11 1.01 – 1.23 0.0328 436 4376 all phecode
292 Neurological disorders Mental Disorders 1.02 0.985 – 1.05 0.332 4621 46260 all phecode
292.1 Aphasia/speech disturbance Mental Disorders 1.07 1.01 – 1.12 0.0182 1504 15074 all phecode
292.2 Mild cognitive impairment Mental Disorders 0.997 0.864 – 1.15 0.963 190 1907 all phecode
292.3 Memory loss Mental Disorders 0.948 0.877 – 1.02 0.177 696 6978 all phecode
292.4 Altered mental status Mental Disorders 1.01 0.968 – 1.06 0.598 2181 21827 all phecode
292.6 Hallucinations Mental Disorders 1.07 0.956 – 1.2 0.234 307 3073 all phecode
293 Symptoms involving head and neck Mental Disorders 1.02 0.971 – 1.06 0.505 2078 20779 all phecode
293.1
Swelling, mass, or lump in head and neck
Swelling, mass, or lump in head and neck [Space-occupying lesion, intracranial NOS]
 Mental Disorders 0.994 0.928 – 1.06 0.856 901 9010 all phecode
295 Schizophrenia and other psychotic disorders Mental Disorders 1.03 0.962 – 1.11 0.382 841 8446 all phecode
295.1 Schizophrenia Mental Disorders 1.02 0.937 – 1.11 0.63 574 5766 all phecode
295.2 Paranoid disorders Mental Disorders 1.02 0.879 – 1.19 0.757 178 1780 all phecode
295.3 Psychosis Mental Disorders 1.08 0.923 – 1.26 0.345 169 1710 all phecode
296 Mood disorders Mental Disorders 1.02 1 – 1.04 0.0497 12372 123822 all phecode
296.1 Bipolar Mental Disorders 0.93 0.873 – 0.99 0.0237 1059 10599 all phecode
296.2 Depression Mental Disorders 1.03 1.01 – 1.05 0.00778 11737 117469 all phecode
296.22 Major depressive disorder Mental Disorders 0.969 0.871 – 1.08 0.569 361 3604 all phecode
297.2 Suicide or self-inflicted injury Mental Disorders 1.06 0.943 – 1.18 0.342 311 3070 all phecode
300 Anxiety disorders Mental Disorders 1 0.975 – 1.02 0.974 6844 68484 all phecode
300.1 Anxiety disorder Mental Disorders 0.995 0.97 – 1.02 0.73 6324 63282 all phecode
300.11 Generalized anxiety disorder Mental Disorders 0.919 0.776 – 1.09 0.329 149 1499 all phecode
300.12 Agorophobia, social phobia, and panic disorder Mental Disorders 0.99 0.917 – 1.07 0.799 707 7065 all phecode
300.13 Phobia Mental Disorders 0.98 0.893 – 1.07 0.665 501 5013 all phecode
300.3 Obsessive-compulsive disorders Mental Disorders 1.02 0.865 – 1.21 0.78 140 1407 all phecode
300.4 Dysthymic disorder Mental Disorders 1.14 0.874 – 1.5 0.328 53 530 all phecode
300.8 Acute reaction to stress Mental Disorders 1.06 0.885 – 1.28 0.511 124 1238 all phecode
300.9 Posttraumatic stress disorder Mental Disorders 0.904 0.743 – 1.1 0.313 113 1129 all phecode
301 Personality disorders Mental Disorders 1.05 0.944 – 1.18 0.351 334 3338 all phecode
301.2 Antisocial/borderline personality disorder Mental Disorders 1.05 0.87 – 1.26 0.634 119 1186 all phecode
302 Sexual and gender identity disorders Mental Disorders 1.17 1.04 – 1.33 0.0113 283 2845 all phecode
303 Psychogenic and somatoform disorders Mental Disorders 1.01 0.924 – 1.12 0.757 467 4679 all phecode
303.3 Psychogenic disorder Mental Disorders 1.05 0.944 – 1.17 0.354 350 3510 all phecode
303.4 Somatoform disorder Mental Disorders 1.02 0.849 – 1.22 0.839 123 1229 all phecode
304 Adjustment reaction Mental Disorders 0.943 0.837 – 1.06 0.338 293 2936 all phecode
305.2 Eating disorder Mental Disorders 1.03 0.839 – 1.27 0.762 90 900 all phecode
306 Other mental disorder Mental Disorders 1.05 1.03 – 1.06 3.94e-13 28056 230087 all phecode
306.9 Tension headache Mental Disorders 1.03 0.92 – 1.16 0.587 315 3148 all phecode
313 Pervasive developmental disorders Mental Disorders 0.825 0.657 – 1.04 0.0998 76 770 all phecode
313.3 Autism Mental Disorders 0.733 0.556 – 0.967 0.0277 53 539 all phecode
315 Develomental delays and disorders Mental Disorders 1.05 0.938 – 1.17 0.422 351 3517 all phecode
315.1 Learning disorder Mental Disorders 0.922 0.783 – 1.08 0.327 161 1610 all phecode
315.2 Speech and language disorder Mental Disorders 0.999 0.804 – 1.24 0.991 88 880 all phecode
316 Substance addiction and disorders Mental Disorders 1.03 0.996 – 1.05 0.0862 5313 53131 all phecode
316.1 Polyneuropathy due to drugs Mental Disorders 0.893 0.7 – 1.14 0.36 60 599 all phecode
317 Alcohol-related disorders Mental Disorders 1.02 0.997 – 1.03 0.102 12696 126892 all phecode
317.1 Alcoholism Mental Disorders 1 0.98 – 1.02 0.858 8890 88923 all phecode
317.11 Alcoholic liver damage Mental Disorders 1.03 0.96 – 1.11 0.399 838 8392 all phecode
318 Tobacco use disorder Mental Disorders 1.06 1.04 – 1.08 2.78e-14 19359 185465 all phecode
320 Meningitis Neurological 1.02 0.928 – 1.13 0.663 444 4447 all phecode
323 Encephalitis Neurological 1.02 0.916 – 1.14 0.708 342 3422 all phecode
323.2 Acute (transverse) myelitis Neurological 0.969 0.766 – 1.23 0.793 74 739 all phecode
324 Other CNS infection and poliomyelitis Neurological 1 0.888 – 1.13 0.989 292 2916 all phecode
327 Sleep disorders Neurological 1.06 1 – 1.13 0.0413 1164 11659 all phecode
327.3 Sleep apnea Neurological 1.09 1.06 – 1.12 7.02e-08 4428 44318 all phecode
327.4 Insomnia Neurological 0.917 0.784 – 1.07 0.281 163 1660 all phecode
327.41 Organic or persistent insomnia Neurological 0.917 0.77 – 1.09 0.334 136 1390 all phecode
331 Other cerebral degenerations Neurological 0.987 0.928 – 1.05 0.665 1142 11416 all phecode
331.1 Hydrocephalus Neurological 0.982 0.896 – 1.08 0.693 502 5014 all phecode
331.9 Cerebral degeneration, unspecified Neurological 0.974 0.882 – 1.07 0.599 430 4298 all phecode
332 Parkinson's disease Neurological 0.949 0.893 – 1.01 0.0929 1126 11254 all phecode
333
Extrapyramidal disease and abnormal movement
Extrapyramidal disease and abnormal movement disorders
 Neurological 1.01 0.946 – 1.09 0.7 894 8954 all phecode
333.1 Essential tremor Neurological 1.02 0.89 – 1.17 0.767 216 2157 all phecode
333.2 Myoclonus Neurological 1.21 0.983 – 1.48 0.0729 96 958 all phecode
333.4 Torsion dystonia Neurological 1.05 0.919 – 1.19 0.498 253 2528 all phecode
334 Degenerative disease of the spinal cord Neurological 1.04 0.994 – 1.09 0.0875 1812 18130 all phecode
334.1 Spinocerebellar disease Neurological 0.998 0.827 – 1.2 0.981 117 1169 all phecode
334.2 Anterior horn cell disease Neurological 1.07 0.938 – 1.22 0.321 245 2446 all phecode
335 Multiple sclerosis Neurological 0.968 0.915 – 1.02 0.264 1340 13385 all phecode
337 Disorders of the autonomic nervous system Neurological 1.07 0.944 – 1.21 0.29 266 2668 all phecode
337.1 Peripheral autonomic neuropathy Neurological 1.06 0.827 – 1.35 0.666 72 719 all phecode
338 Pain Neurological 1.05 0.977 – 1.13 0.185 768 7692 all phecode
338.1 Acute pain Neurological 1.03 0.932 – 1.14 0.547 394 3937 all phecode
338.2 Chronic pain Neurological 1.07 0.961 – 1.18 0.225 380 3817 all phecode
339 Other headache syndromes Neurological 1.04 1.02 – 1.06 0.000886 7819 78241 all phecode
340 Migraine Neurological 0.989 0.952 – 1.03 0.578 2860 28602 all phecode
340.1 Migrain with aura Neurological 0.853 0.741 – 0.982 0.0267 212 2117 all phecode
341
Other demyelinating diseases of central nervous
Other demyelinating diseases of central nervous system
 Neurological 1.05 0.919 – 1.19 0.502 252 2535 all phecode
342 Hemiplegia Neurological 1.09 1.03 – 1.15 0.00238 1494 14947 all phecode
343 Infantile cerebral palsy Neurological 1.04 0.88 – 1.23 0.642 145 1450 all phecode
344 Other paralytic syndromes Neurological 1.06 0.977 – 1.15 0.162 658 6593 all phecode
345 Epilepsy, recurrent seizures, convulsions Neurological 1 0.976 – 1.03 0.758 5023 50270 all phecode
345.1 Epilepsy Neurological 1.01 0.941 – 1.08 0.804 866 8661 all phecode
345.11 Generalized convulsive epilepsy Neurological 1.06 0.96 – 1.16 0.258 439 4385 all phecode
345.12 Partial epilepsy Neurological 0.964 0.852 – 1.09 0.563 277 2776 all phecode
345.3 Convulsions Neurological 1 0.96 – 1.05 0.905 2235 22339 all phecode
346.1
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of skull and head
 Neurological 1.05 0.882 – 1.26 0.571 144 1438 all phecode
348 Other conditions of brain Neurological 1.07 0.991 – 1.15 0.084 778 7808 all phecode
348.2 Cerebral edema and compression of brain Neurological 1.06 0.936 – 1.2 0.365 268 2678 all phecode
348.4 Cerebral cysts Neurological 0.929 0.778 – 1.11 0.414 133 1350 all phecode
348.7 Coma Neurological 1.04 0.93 – 1.15 0.525 358 3596 all phecode
348.8 Encephalopathy, not elsewhere classified Neurological 1.1 0.963 – 1.25 0.162 249 2504 all phecode
348.9 Other conditions of brain, NOS Neurological 0.953 0.859 – 1.06 0.359 390 3899 all phecode
349
Other and unspecified disorders of the nervous
Other and unspecified disorders of the nervous system
 Neurological 1.01 0.902 – 1.12 0.906 342 3414 all phecode
350 Abnormal movement Neurological 1 0.963 – 1.04 0.917 2671 26722 all phecode
350.1 Abnormal involuntary movements Neurological 0.988 0.923 – 1.06 0.734 887 8852 all phecode
350.2 Abnormality of gait Neurological 0.987 0.937 – 1.04 0.616 1596 15969 all phecode
350.3 Lack of coordination Neurological 1.06 0.949 – 1.17 0.319 363 3638 all phecode
350.6 Disturbances of sensation of smell and taste Neurological 0.97 0.73 – 1.29 0.833 54 540 all phecode
351 Other peripheral nerve disorders Neurological 1.07 1.05 – 1.08 2.17e-11 12420 124321 all phecode
352 Disorders of other cranial nerves Neurological 1.03 0.973 – 1.09 0.318 1370 13706 all phecode
352.1 Trigeminal nerve disorders [CN5] Neurological 1.02 0.923 – 1.12 0.72 463 4638 all phecode
352.2 Facial nerve disorders [CN7] Neurological 1.04 0.974 – 1.12 0.229 880 8795 all phecode
353 Nerve root and plexus disorders Neurological 1.06 0.998 – 1.13 0.0575 1131 11319 all phecode
353.1 Nerve plexus lesions Neurological 1.09 0.902 – 1.32 0.373 114 1138 all phecode
353.2 Nerve root lesions Neurological 1.14 0.869 – 1.5 0.343 57 570 all phecode
356 Hereditary and idiopathic peripheral neuropathy Neurological 0.899 0.758 – 1.07 0.218 152 1520 all phecode
357 Inflammatory and toxic neuropathy Neurological 1.1 1.04 – 1.16 0.00127 1361 13648 all phecode
358 Myoneural disorders Neurological 1 0.871 – 1.16 0.95 211 2109 all phecode
358.1 Myasthenia gravis Neurological 1.03 0.889 – 1.19 0.701 192 1919 all phecode
359 Muscular dystrophies and other myopathies Neurological 1.03 0.938 – 1.13 0.532 465 4646 all phecode
359.1 Muscular dystrophies Neurological 0.958 0.8 – 1.15 0.643 122 1219 all phecode
359.2 Myopathy Neurological 1.03 0.928 – 1.15 0.552 360 3597 all phecode
360 Disorders of the globe Sense Organs 0.991 0.885 – 1.11 0.877 337 3367 all phecode
360.2 Progressive myopia Sense Organs 0.989 0.865 – 1.13 0.877 251 2508 all phecode
361 Retinal detachments and defects Sense Organs 0.996 0.961 – 1.03 0.833 3246 32453 all phecode
361.1 Retinal detachment with retinal defect Sense Organs 0.987 0.934 – 1.04 0.634 1389 13884 all phecode
361.2 Retinoschisis and retinal cysts Sense Organs 0.989 0.778 – 1.26 0.925 68 680 all phecode
362 Other retinal disorders Sense Organs 1.03 0.999 – 1.07 0.0538 3836 38370 all phecode
362.2
Degeneration of macula and posterior pole of
Degeneration of macula and posterior pole of retina
 Sense Organs 1 0.959 – 1.05 0.936 2182 21813 all phecode
362.29 Macular degeneration (senile) of retina NOS Sense Organs 1 0.959 – 1.05 0.92 2179 21783 all phecode
362.3 Other nondiabetic retinopathy Sense Organs 1.21 1.03 – 1.42 0.0231 161 1609 all phecode
362.31 Separation of retinal layers Sense Organs 1.21 0.981 – 1.49 0.0747 99 990 all phecode
362.4 Retinal vascular changes and abnomalities Sense Organs 1.05 0.978 – 1.13 0.175 848 8477 all phecode
362.6 Peripheral retinal degenerations Sense Organs 0.878 0.754 – 1.02 0.0904 182 1827 all phecode
362.7 Hereditary retinal dystrophies Sense Organs 0.939 0.746 – 1.18 0.595 82 812 all phecode
362.8 Retinal hemorrhage/ischemia Sense Organs 1.12 0.927 – 1.36 0.238 116 1159 all phecode
363
Chorioretinal inflammations, scars, and other
Chorioretinal inflammations, scars, and other disorders of choroid
 Sense Organs 0.935 0.797 – 1.1 0.413 170 1699 all phecode
363.3 Chorioretinal scars Sense Organs 0.904 0.707 – 1.16 0.423 69 690 all phecode
364 Corneal opacity and other disorders of cornea Sense Organs 0.931 0.859 – 1.01 0.0801 647 6485 all phecode
364.1 Corneal opacity Sense Organs 1.05 0.853 – 1.3 0.639 90 910 all phecode
364.2 Corneal edema Sense Organs 0.978 0.775 – 1.23 0.851 79 800 all phecode
364.4 Corneal degenerations Sense Organs 0.962 0.831 – 1.11 0.602 201 2017 all phecode
364.41 Keratoconus Sense Organs 0.86 0.687 – 1.08 0.185 86 869 all phecode
364.5 Corneal dystrophy Sense Organs 0.901 0.784 – 1.03 0.139 211 2109 all phecode
364.9 Cornea replaced by transplant Sense Organs 0.99 0.81 – 1.21 0.919 100 1000 all phecode
365 Glaucoma Sense Organs 1.04 1.01 – 1.08 0.00844 4408 44136 all phecode
365.1 Open-angle glaucoma Sense Organs 1.07 1.01 – 1.14 0.029 1032 10346 all phecode
365.11 Primary open angle glaucoma Sense Organs 1.07 1.01 – 1.14 0.0296 1026 10287 all phecode
365.2 Primary angle-closure glaucoma Sense Organs 0.948 0.878 – 1.02 0.18 698 6996 all phecode
366 Cataract Sense Organs 1.04 1.02 – 1.05 2.68e-07 19926 168711 all phecode
366.1 Nonsenile Cataract Sense Organs 0.953 0.744 – 1.22 0.704 69 700 all phecode
366.2 Senile cataract Sense Organs 1.04 1.02 – 1.07 0.000354 8231 81909 all phecode
366.3 Traumatic cataract Sense Organs 0.864 0.707 – 1.06 0.153 102 1019 all phecode
367
Disorders of refraction and accommodation
Disorders of refraction and accommodation; blindness and low vision
 Sense Organs 1 0.963 – 1.05 0.818 2408 24092 all phecode
367.1 Myopia Sense Organs 1.03 0.968 – 1.09 0.379 1251 12519 all phecode
367.2 Astigmatism Sense Organs 1.12 0.961 – 1.31 0.145 190 1899 all phecode
367.8 Hypermetropia Sense Organs 0.996 0.873 – 1.14 0.953 253 2530 all phecode
367.9 Blindness and low vision Sense Organs 0.959 0.887 – 1.04 0.29 719 7198 all phecode
368 Visual disturbances Sense Organs 1.03 0.993 – 1.07 0.108 2962 29648 all phecode
368.1 Amblyopia Sense Organs 1 0.918 – 1.1 0.931 532 5322 all phecode
368.2 Diplopia and disorders of binocular vision Sense Organs 1.02 0.944 – 1.1 0.618 727 7288 all phecode
368.3 Anisometropia Sense Organs 0.977 0.821 – 1.16 0.796 154 1548 all phecode
368.4 Visual field defects Sense Organs 1.04 0.933 – 1.17 0.459 333 3327 all phecode
368.9 Subjective visual disturbances Sense Organs 1.06 0.974 – 1.15 0.176 612 6115 all phecode
369 Infection of the eye Sense Organs 0.953 0.873 – 1.04 0.278 553 5544 all phecode
369.2 Eye infection, viral Sense Organs 0.841 0.701 – 1.01 0.061 125 1257 all phecode
369.5 Conjunctivitis, infectious Sense Organs 0.891 0.775 – 1.02 0.103 213 2128 all phecode
370 Keratitis Sense Organs 0.892 0.792 – 1.01 0.061 286 2855 all phecode
370.1 Corneal ulcer Sense Organs 0.77 0.648 – 0.914 0.00282 141 1408 all phecode
371 Inflammation of the eye Sense Organs 1 0.965 – 1.04 0.951 3045 30480 all phecode
371.1 Uveitis, noninfectious or NOS Sense Organs 1.04 0.945 – 1.14 0.439 482 4821 all phecode
371.3 Inflammation of eyelids Sense Organs 0.997 0.956 – 1.04 0.888 2353 23555 all phecode
372 Disorders of conjunctiva Sense Organs 1 0.932 – 1.08 0.912 760 7602 all phecode
374 Other disorders of eyelids Sense Organs 1.03 0.998 – 1.05 0.0646 5680 56807 all phecode
374.1 Ectropion or entropion Sense Organs 0.988 0.929 – 1.05 0.711 1063 10645 all phecode
374.3 Ptosis of eyelid Sense Organs 0.994 0.948 – 1.04 0.814 1825 18232 all phecode
375 Disorders of lacrimal system Sense Organs 1.04 0.997 – 1.09 0.0648 2204 22031 all phecode
375.2 Epiphora Sense Organs 1.02 0.948 – 1.09 0.661 898 8969 all phecode
376 Disorders of the orbit Sense Organs 0.861 0.691 – 1.07 0.179 86 859 all phecode
377 Disorders of optic nerve and visual pathways Sense Organs 1.14 1.03 – 1.28 0.0158 361 3618 all phecode
377.1 Optic atrophy Sense Organs 1.02 0.762 – 1.36 0.909 56 570 all phecode
377.3 Optic neuritis/neuropathy Sense Organs 1.15 0.957 – 1.39 0.136 125 1249 all phecode
378
Strabismus and other disorders of binocular eye
Strabismus and other disorders of binocular eye movements
 Sense Organs 0.996 0.943 – 1.05 0.898 1410 14116 all phecode
378.1 Strabismus (not specified as paralytic) Sense Organs 0.994 0.929 – 1.06 0.872 909 9082 all phecode
378.2 Nystagmus and other irregular eye movements Sense Organs 1.11 0.966 – 1.28 0.137 213 2138 all phecode
378.5 Paralytic strabismus Sense Organs 0.948 0.837 – 1.07 0.398 275 2755 all phecode
379 Other disorders of eye Sense Organs 1.04 1 – 1.07 0.0421 3703 37063 all phecode
379.2 Disorders of vitreous body Sense Organs 1.05 0.995 – 1.11 0.074 1367 13665 all phecode
379.3 Aphakia and other disorders of lens Sense Organs 1.04 0.99 – 1.09 0.125 1813 18134 all phecode
379.4 Anomalies of pupillary function Sense Organs 1.11 0.879 – 1.41 0.371 71 710 all phecode
379.5 Disorders of iris and ciliary body Sense Organs 1.02 0.923 – 1.13 0.675 400 4028 all phecode
379.9 Pain, swelling or discharge of eye Sense Organs 1.06 0.906 – 1.24 0.473 169 1690 all phecode
380 Disorders of external ear Sense Organs 1.07 0.987 – 1.16 0.0997 642 6413 all phecode
380.1 Otitis externa Sense Organs 1.08 0.988 – 1.18 0.0893 509 5107 all phecode
380.4 Impacted cerumen Sense Organs 1.14 1.02 – 1.27 0.0184 362 3614 all phecode
381 Otitis media and Eustachian tube disorders Sense Organs 1.07 1.02 – 1.12 0.00242 2150 21493 all phecode
381.1 Otitis media Sense Organs 1.09 1.04 – 1.15 0.000302 1767 17668 all phecode
381.11 Suppurative and unspecified otitis media Sense Organs 1.12 1.05 – 1.21 0.00135 852 8524 all phecode
381.2 Eustachian tube disorders Sense Organs 1 0.866 – 1.16 0.993 193 1929 all phecode
381.3 Mastoiditis & related conditions Sense Organs 1.01 0.864 – 1.19 0.877 171 1709 all phecode
381.9 Otorrhea Sense Organs 1.1 0.972 – 1.24 0.134 281 2807 all phecode
382 Otalgia Sense Organs 0.93 0.828 – 1.05 0.228 308 3084 all phecode
383 Otosclerosis Sense Organs 0.859 0.764 – 0.965 0.0106 309 3090 all phecode
384 Other disorders of tympanic membrane Sense Organs 1.06 1 – 1.12 0.0446 1299 12991 all phecode
384.4 Perforation of tympanic membrane Sense Organs 1.07 1.01 – 1.14 0.0329 1043 10432 all phecode
385 Other disorders of middle ear and mastoid Sense Organs 1.05 0.976 – 1.13 0.188 783 7837 all phecode
385.3 Cholesteatoma Sense Organs 1.05 0.965 – 1.14 0.262 607 6078 all phecode
385.5
Tympanosclerosis and middle ear disease related
Tympanosclerosis and middle ear disease related to otitis media
 Sense Organs 1.12 0.98 – 1.28 0.0958 241 2409 all phecode
386
Vertiginous syndromes and other disorders of
Vertiginous syndromes and other disorders of vestibular system
 Sense Organs 0.993 0.945 – 1.04 0.767 1736 17373 all phecode
386.1 Meniere's disease Sense Organs 0.979 0.9 – 1.07 0.632 576 5768 all phecode
386.2 Peripheral or central vertigo Sense Organs 0.958 0.862 – 1.07 0.428 377 3763 all phecode
386.3 Labyrinthitis Sense Organs 1.01 0.939 – 1.09 0.764 765 7664 all phecode
386.9
Dizziness and giddiness (Light-headedness and
Dizziness and giddiness (Light-headedness and vertigo)
 Sense Organs 1.03 0.998 – 1.06 0.068 4582 45806 all phecode
388 Other disorders of ear Sense Organs 1.07 0.927 – 1.23 0.362 202 2017 all phecode
389 Hearing loss Sense Organs 1.01 0.977 – 1.04 0.605 4188 41944 all phecode
389.1 Sensorineural hearing loss Sense Organs 1.06 0.964 – 1.17 0.227 456 4553 all phecode
389.2 Conductive hearing loss Sense Organs 1.01 0.92 – 1.12 0.773 450 4497 all phecode
389.4 Tinnitus Sense Organs 1.03 0.94 – 1.13 0.532 513 5134 all phecode
394 Rheumatic disease of the heart valves Circulatory System 1 0.971 – 1.03 0.993 4899 48974 all phecode
394.2 Mitral valve disease Circulatory System 0.996 0.959 – 1.03 0.835 2993 29922 all phecode
394.3 Aortic valve disease Circulatory System 1.01 0.953 – 1.07 0.739 1282 12814 all phecode
394.7 Disease of tricuspid valve Circulatory System 0.99 0.929 – 1.05 0.753 1058 10566 all phecode
395 Heart valve disorders Circulatory System 0.999 0.968 – 1.03 0.96 4223 42219 all phecode
395.1 Nonrheumatic mitral valve disorders Circulatory System 0.996 0.959 – 1.04 0.851 2891 28900 all phecode
395.2 Nonrheumatic aortic valve disorders Circulatory System 1.09 0.962 – 1.23 0.177 276 2766 all phecode
395.3 Nonrheumatic tricuspid valve disorders Circulatory System 0.97 0.799 – 1.18 0.759 105 1039 all phecode
395.4 Nonrheumatic pulmonary valve disorders Circulatory System 1.05 0.862 – 1.29 0.604 97 970 all phecode
395.6 Heart valve replaced Circulatory System 0.993 0.942 – 1.05 0.804 1495 14942 all phecode
396 Abnormal heart sounds Circulatory System 1.05 0.982 – 1.12 0.161 1048 10468 all phecode
401 Hypertension Circulatory System 1.12 1.11 – 1.13 1.73e-156 73956 266957 all phecode
401.1 Essential hypertension Circulatory System 1.12 1.11 – 1.13 8.83e-157 73731 266739 all phecode
401.2 Hypertensive heart and/or renal disease Circulatory System 1.13 1.08 – 1.19 2.06e-07 1898 19031 all phecode
401.21 Hypertensive heart disease Circulatory System 1.12 1.01 – 1.25 0.0373 370 3699 all phecode
401.22 Hypertensive chronic kidney disease Circulatory System 1.13 1.07 – 1.19 4.58e-06 1543 15483 all phecode
401.3 Other hypertensive complications Circulatory System 1.07 0.902 – 1.27 0.44 144 1438 all phecode
402
Elevated blood pressure reading without
Elevated blood pressure reading without diagnosis of hypertension
 Circulatory System 1.16 1.09 – 1.22 1.51e-07 1479 14786 all phecode
411 Ischemic Heart Disease Circulatory System 1.1 1.08 – 1.11 5.91e-52 31245 210714 all phecode
411.1 Unstable angina (intermediate coronary syndrome) Circulatory System 1.1 1.07 – 1.13 1.5e-10 5152 51498 all phecode
411.2 Myocardial infarction Circulatory System 1.11 1.09 – 1.14 2.13e-29 11950 112699 all phecode
411.3 Angina pectoris Circulatory System 1.11 1.09 – 1.13 2.73e-35 15888 143745 all phecode
411.4 Coronary atherosclerosis Circulatory System 1.1 1.09 – 1.12 1.95e-39 20171 154621 all phecode
411.41 Aneurysm and dissection of heart Circulatory System 0.932 0.863 – 1.01 0.0758 700 6997 all phecode
411.8
Other chronic ischemic heart disease
Other chronic ischemic heart disease, unspecified
 Circulatory System 1.11 1.09 – 1.13 5.37e-36 15290 131798 all phecode
411.9
Other acute and subacute forms of ischemic
Other acute and subacute forms of ischemic heart disease
 Circulatory System 1.15 1.08 – 1.22 4.79e-06 1218 12166 all phecode
414 Other forms of chronic heart disease Circulatory System 1.12 1.06 – 1.17 7.12e-06 1823 18228 all phecode
414.2 ASCVD Circulatory System 1.01 0.793 – 1.29 0.919 72 719 all phecode
415 Pulmonary heart disease Circulatory System 1.01 0.984 – 1.05 0.357 4476 44810 all phecode
415.11 Pulmonary embolism and infarction, acute Circulatory System 1.01 0.796 – 1.29 0.906 75 750 all phecode
415.2 Chronic pulmonary heart disease Circulatory System 1.04 0.956 – 1.13 0.366 601 6002 all phecode
415.21 Primary pulmonary hypertension Circulatory System 1.12 1.02 – 1.23 0.0232 448 4475 all phecode
416 Cardiomegaly Circulatory System 1.09 1.05 – 1.13 2.44e-05 2680 26793 all phecode
418 Nonspecific chest pain Circulatory System 1.05 1.04 – 1.06 3.81e-15 28599 270106 all phecode
418.1 Precordial pain Circulatory System 1.09 1.05 – 1.13 1.27e-06 3551 35541 all phecode
420 Carditis Circulatory System 0.961 0.919 – 1.01 0.0868 2106 21053 all phecode
420.1 Myocarditis Circulatory System 0.86 0.718 – 1.03 0.103 127 1267 all phecode
420.2 Pericarditis Circulatory System 0.958 0.905 – 1.01 0.131 1338 13371 all phecode
420.21 Acute pericarditis Circulatory System 0.961 0.84 – 1.1 0.57 223 2227 all phecode
420.22 Chronic pericarditis Circulatory System 0.925 0.769 – 1.11 0.406 113 1129 all phecode
420.3 Endocarditis Circulatory System 0.985 0.912 – 1.06 0.696 719 7194 all phecode
425 Cardiomyopathy Circulatory System 1.04 0.986 – 1.11 0.14 1271 12699 all phecode
425.1 Primary/intrinsic cardiomyopathies Circulatory System 1.04 0.983 – 1.11 0.162 1236 12349 all phecode
425.11 Hypertrophic obstructive cardiomyopathy Circulatory System 0.999 0.836 – 1.19 0.987 133 1329 all phecode
425.12 Other hypertrophic cardiomyopathy Circulatory System 0.851 0.722 – 1 0.0528 163 1629 all phecode
425.8 Other cardiomyopathy Circulatory System 0.819 0.63 – 1.07 0.137 60 600 all phecode
426 Cardiac conduction disorders Circulatory System 1.03 1.01 – 1.06 0.0176 6910 69146 all phecode
426.2 Atrioventricular [AV] block Circulatory System 1.03 0.981 – 1.07 0.263 2114 21162 all phecode
426.21 First degree AV block Circulatory System 1.03 0.964 – 1.1 0.383 986 9867 all phecode
426.23 Second degree AV block Circulatory System 1.06 0.96 – 1.16 0.259 452 4515 all phecode
426.24 Atrioventricular block, complete Circulatory System 0.995 0.914 – 1.08 0.911 587 5868 all phecode
426.25 Other heart block Circulatory System 0.945 0.79 – 1.13 0.532 131 1318 all phecode
426.3 Bundle branch block Circulatory System 1.04 1 – 1.07 0.044 3336 33359 all phecode
426.31 Right bundle branch block Circulatory System 1.01 0.957 – 1.06 0.735 1494 14933 all phecode
426.32 Left bundle branch block Circulatory System 1.07 1.02 – 1.12 0.00677 1750 17503 all phecode
426.4 Anomalous atrioventricular excitation Circulatory System 0.944 0.826 – 1.08 0.398 233 2328 all phecode
426.8 Other cardiac conduction disorders Circulatory System 0.975 0.744 – 1.28 0.857 60 600 all phecode
426.9 Cardiac pacemaker/device in situ Circulatory System 1.04 0.995 – 1.08 0.0836 2475 24774 all phecode
426.91 Cardiac pacemaker in situ Circulatory System 1.03 0.983 – 1.07 0.23 2274 22762 all phecode
427 Cardiac dysrhythmias Circulatory System 1.02 1.01 – 1.03 0.00569 24207 206016 all phecode
427.1 Paroxysmal tachycardia, unspecified Circulatory System 1.04 1.01 – 1.08 0.0198 3199 32017 all phecode
427.11 Paroxysmal supraventricular tachycardia Circulatory System 1.03 0.991 – 1.08 0.126 2344 23474 all phecode
427.12 Paroxysmal ventricular tachycardia Circulatory System 1.08 1.01 – 1.16 0.0195 936 9365 all phecode
427.2 Atrial fibrillation and flutter Circulatory System 1.02 1 – 1.04 0.0212 14628 133501 all phecode
427.3 Other specified cardiac dysrhythmias Circulatory System 1.02 0.987 – 1.06 0.202 3228 32281 all phecode
427.4 Cardiac arrest and ventricular fibrillation Circulatory System 1.03 0.972 – 1.1 0.297 1193 11915 all phecode
427.41 Ventricular fibrillation and flutter Circulatory System 1.03 0.917 – 1.15 0.659 344 3437 all phecode
427.42 Cardiac arrest Circulatory System 1.04 0.973 – 1.11 0.25 990 9890 all phecode
427.5 Arrhythmia (cardiac) NOS Circulatory System 0.978 0.916 – 1.05 0.519 952 9541 all phecode
427.6 Premature beats Circulatory System 1.01 0.927 – 1.11 0.768 535 5358 all phecode
427.61 Supraventricular premature beats Circulatory System 0.996 0.827 – 1.2 0.963 117 1168 all phecode
427.7 Tachycardia NOS Circulatory System 1.03 0.985 – 1.08 0.193 2185 21865 all phecode
427.8 Sinoatrial node dysfunction (Bradycardia) Circulatory System 0.949 0.857 – 1.05 0.32 402 4029 all phecode
427.9 Palpitations Circulatory System 1.01 0.977 – 1.04 0.544 3811 38105 all phecode
428 Congestive heart failure; nonhypertensive Circulatory System 1.09 1.06 – 1.12 1.53e-09 5605 56018 all phecode
428.1 Congestive heart failure (CHF) NOS Circulatory System 1.11 1.06 – 1.16 2.58e-06 2111 21108 all phecode
428.2 Heart failure NOS Circulatory System 1.08 1.05 – 1.12 2.6e-07 4455 44524 all phecode
429
Ill-defined descriptions and complications of
Ill-defined descriptions and complications of heart disease
 Circulatory System 1.01 0.933 – 1.09 0.858 716 7168 all phecode
429.1 Heart transplant/surgery Circulatory System 0.974 0.754 – 1.26 0.842 64 639 all phecode
429.2 Abnormal function study of cardiovascular system Circulatory System 1 0.915 – 1.09 0.992 522 5211 all phecode
429.3 Symptoms involving cardiovascular system Circulatory System 1.04 0.901 – 1.21 0.578 196 1978 all phecode
430 Intracranial hemorrhage Circulatory System 0.997 0.951 – 1.05 0.902 1883 18825 all phecode
430.1 Subarachnoid hemorrhage Circulatory System 0.978 0.912 – 1.05 0.532 836 8353 all phecode
430.2 Intracerebral hemorrhage Circulatory System 1.04 0.964 – 1.12 0.321 765 7656 all phecode
430.3 Subdural hemorrhage Circulatory System 0.88 0.775 – 0.998 0.0462 267 2667 all phecode
433 Cerebrovascular disease Circulatory System 1.05 1.03 – 1.07 2.73e-05 8749 87456 all phecode
433.1 Occlusion and stenosis of precerebral arteries Circulatory System 1.12 1.05 – 1.18 0.00035 1185 11825 all phecode
433.12 Cerebral atherosclerosis Circulatory System 1.08 0.942 – 1.24 0.266 227 2267 all phecode
433.2 Occlusion of cerebral arteries Circulatory System 1.07 1.04 – 1.11 2.18e-05 4233 42320 all phecode
433.21
Cerebral artery occlusion, with cerebral
Cerebral artery occlusion, with cerebral infarction
 Circulatory System 1.12 1.06 – 1.17 1.92e-05 1680 16794 all phecode
433.3 Cerebral ischemia Circulatory System 1.02 0.982 – 1.06 0.307 2895 28989 all phecode
433.31 Transient cerebral ischemia Circulatory System 1.03 0.988 – 1.08 0.157 2135 21379 all phecode
433.5 Cerebral aneurysm Circulatory System 0.994 0.897 – 1.1 0.91 394 3939 all phecode
433.8 Late effects of cerebrovascular disease Circulatory System 1.1 1.04 – 1.16 0.00121 1279 12783 all phecode
440 Atherosclerosis Circulatory System 1.19 1.12 – 1.25 1.28e-09 1380 13822 all phecode
440.1 Atherosclerosis of renal artery Circulatory System 1.19 0.982 – 1.44 0.0768 113 1129 all phecode
440.2 Atherosclerosis of the extremities Circulatory System 1.22 1.13 – 1.31 9.79e-08 805 8070 all phecode
440.9 Atherosclerosis of aorta Circulatory System 1.13 1 – 1.28 0.0492 287 2867 all phecode
441 Vascular insufficiency of intestine Circulatory System 1.02 0.942 – 1.11 0.578 614 6154 all phecode
441.1 Acute vascular insufficiency of intestine Circulatory System 0.996 0.881 – 1.13 0.949 283 2827 all phecode
442 Other aneurysm Circulatory System 1 0.957 – 1.05 0.886 1892 18959 all phecode
442.1 Aortic aneurysm Circulatory System 0.984 0.932 – 1.04 0.551 1458 14625 all phecode
442.11 Abdominal aortic aneurysm Circulatory System 1.02 0.955 – 1.09 0.541 931 9341 all phecode
442.2 Aneurysm of iliac artery Circulatory System 1.04 0.852 – 1.28 0.681 102 1019 all phecode
442.3 Aneurysm of artery of lower extremity Circulatory System 1.1 0.942 – 1.29 0.224 169 1696 all phecode
442.4 Arterial dissection Circulatory System 0.798 0.604 – 1.05 0.11 54 549 all phecode
442.8 Aneurysm of other specified artery Circulatory System 1.03 0.896 – 1.19 0.643 203 2028 all phecode
443 Peripheral vascular disease Circulatory System 1.13 1.09 – 1.17 7.36e-13 3921 39273 all phecode
443.1 Raynaud's syndrome Circulatory System 1 0.94 – 1.06 0.987 1145 11438 all phecode
443.7
Peripheral angiopathy in diseases classified
Peripheral angiopathy in diseases classified elsewhere
 Circulatory System 1.57 1.41 – 1.74 6.1e-17 384 3878 all phecode
443.8 Other specified peripheral vascular diseases Circulatory System 1.11 1.07 – 1.15 2.75e-09 3686 36906 all phecode
443.9 Peripheral vascular disease, unspecified Circulatory System 1.16 1.12 – 1.21 4.06e-13 2579 25846 all phecode
444 Arterial embolism and thrombosis Circulatory System 1.14 1.06 – 1.22 0.00018 922 9251 all phecode
444.1
Arterial embolism and thrombosis of lower
Arterial embolism and thrombosis of lower extremity artery
 Circulatory System 1.25 1.15 – 1.36 4.14e-07 554 5552 all phecode
446 Polyarteritis nodosa and allied conditions Circulatory System 1.02 0.953 – 1.1 0.518 822 8226 all phecode
446.4 Wegener's granulomatosis Circulatory System 1.02 0.883 – 1.18 0.767 188 1878 all phecode
446.5 Giant cell arteritis Circulatory System 1 0.903 – 1.11 0.955 388 3879 all phecode
446.9 Arteritis NOS Circulatory System 1.08 0.952 – 1.24 0.224 239 2400 all phecode
447 Other disorders of arteries and arterioles Circulatory System 1.15 1.09 – 1.22 8.8e-07 1327 13316 all phecode
447.1 Stricture of artery Circulatory System 1.24 1.16 – 1.33 1.76e-09 868 8712 all phecode
448 Disease of capillaries Circulatory System 0.879 0.742 – 1.04 0.136 142 1420 all phecode
450 Noninfectious disorders of lymphatic channels Circulatory System 0.985 0.912 – 1.06 0.697 704 7034 all phecode
451 Phlebitis and thrombophlebitis Circulatory System 1.07 1.04 – 1.11 5.42e-05 3955 39683 all phecode
451.2
Phlebitis and thrombophlebitis of lower
Phlebitis and thrombophlebitis of lower extremities
 Circulatory System 1.08 1.04 – 1.12 1.04e-05 3683 36977 all phecode
452 Other venous embolism and thrombosis Circulatory System 0.986 0.904 – 1.08 0.748 564 5645 all phecode
454 Varicose veins Circulatory System 0.996 0.977 – 1.02 0.695 11180 112047 all phecode
454.1 Varicose veins of lower extremity Circulatory System 0.994 0.975 – 1.01 0.546 11503 115272 all phecode
454.11 Varicose veins of lower extremity, symptomtic Circulatory System 0.987 0.909 – 1.07 0.767 624 6325 all phecode
455 Hemorrhoids Circulatory System 1 0.99 – 1.02 0.642 23452 234585 all phecode
456 Chronic venous insufficiency [CVI] Circulatory System 0.902 0.777 – 1.05 0.178 184 1868 all phecode
457
Encounter for long-term (current) use of
Encounter for long-term (current) use of anticoagulants, antithrombotics, aspirin
 Circulatory System 1.09 0.88 – 1.35 0.436 97 967 all phecode
458 Hypotension Circulatory System 1.01 0.986 – 1.04 0.335 5769 57772 all phecode
458.1 Orthostatic hypotension Circulatory System 1.02 0.968 – 1.08 0.408 1335 13376 all phecode
458.2 Iatrogenic hypotension Circulatory System 1.13 0.988 – 1.29 0.0733 235 2348 all phecode
458.9 Hypotension NOS Circulatory System 1.02 0.987 – 1.06 0.215 3494 35005 all phecode
459 Other disorders of circulatory system Circulatory System 1.04 1.02 – 1.05 6.76e-06 16268 160790 all phecode
459.1 Hemorrhage NOS Circulatory System 1.07 0.897 – 1.27 0.472 142 1420 all phecode
459.9 Circulatory disease NEC Circulatory System 1.04 1.02 – 1.06 6.32e-06 16103 159422 all phecode
464 Acute sinusitis Respiratory 1.06 0.912 – 1.23 0.447 196 1957 all phecode
465
Acute upper respiratory infections of multiple
Acute upper respiratory infections of multiple or unspecified sites
 Respiratory 1.04 0.993 – 1.08 0.103 2283 22827 all phecode
465.2 Acute pharyngitis Respiratory 1.05 0.977 – 1.13 0.187 835 8348 all phecode
465.4 Acute laryngitis and tracheitis Respiratory 1.01 0.866 – 1.19 0.871 165 1649 all phecode
470 Septal Deviations/Turbinate Hypertrophy Respiratory 1.02 0.987 – 1.05 0.259 4654 46553 all phecode
471 Nasal polyps Respiratory 1.01 0.97 – 1.04 0.768 3297 32973 all phecode
472 Chronic pharyngitis and nasopharyngitis Respiratory 0.986 0.922 – 1.05 0.67 960 9594 all phecode
473 Diseases of the larynx and vocal cords Respiratory 1.02 0.975 – 1.06 0.449 2554 25548 all phecode
473.1 Chronic laryngitis Respiratory 0.902 0.743 – 1.1 0.297 104 1038 all phecode
473.3 Paralysis/spasm of vocal cords or larynx Respiratory 1.05 0.921 – 1.19 0.482 264 2647 all phecode
473.4 Voice disturbance Respiratory 0.977 0.918 – 1.04 0.472 1080 10789 all phecode
474 Acute and chronic tonsillitis Respiratory 1.03 0.977 – 1.08 0.304 1772 17710 all phecode
474.1 Acute tonsillitis Respiratory 1.03 0.943 – 1.12 0.541 549 5486 all phecode
474.2 Chronic tonsillitis and adenoiditis Respiratory 1.06 0.994 – 1.13 0.0749 1122 11199 all phecode
475 Chronic sinusitis Respiratory 1.03 0.985 – 1.07 0.223 2589 25882 all phecode
476 Allergic rhinitis Respiratory 0.982 0.921 – 1.05 0.582 1055 10563 all phecode
477 Epistaxis or throat hemorrhage Respiratory 1.03 0.984 – 1.07 0.226 2447 24452 all phecode
478 Throat pain Respiratory 1.07 0.958 – 1.18 0.24 377 3789 all phecode
479 Other upper respiratory disease Respiratory 1.01 0.982 – 1.05 0.388 4074 40737 all phecode
480 Pneumonia Respiratory 1.02 1 – 1.04 0.025 10336 103397 all phecode
480.1 Bacterial pneumonia Respiratory 1.01 0.981 – 1.03 0.662 6637 66410 all phecode
480.11 Pneumococcal pneumonia Respiratory 0.99 0.964 – 1.02 0.468 5883 58863 all phecode
480.12 Pseudomonal pneumonia Respiratory 1.21 0.986 – 1.48 0.0686 93 929 all phecode
480.2 Viral pneumonia Respiratory 1.22 0.959 – 1.54 0.107 72 720 all phecode
480.3 Pneumonia due to fungus (mycoses) Respiratory 0.925 0.755 – 1.13 0.449 99 989 all phecode
480.5 Bronchopneumonia and lung abscess Respiratory 1.02 0.951 – 1.1 0.557 794 7951 all phecode
481 Influenza Respiratory 1 0.893 – 1.12 0.996 328 3278 all phecode
483 Acute bronchitis and bronchiolitis Respiratory 1.11 0.955 – 1.28 0.179 193 1930 all phecode
495 Asthma Respiratory 1.04 1.03 – 1.06 3.35e-11 25689 250406 all phecode
495.2 Asthma with exacerbation Respiratory 1.09 0.956 – 1.25 0.195 250 2510 all phecode
496 Chronic airway obstruction Respiratory 1.05 1.03 – 1.07 9.1e-07 10424 101546 all phecode
496.1 Emphysema Respiratory 0.997 0.949 – 1.05 0.895 1743 17438 all phecode
496.2 Chronic bronchitis Respiratory 1.03 0.996 – 1.07 0.079 2947 29498 all phecode
496.21 Obstructive chronic bronchitis Respiratory 1.03 0.995 – 1.08 0.089 2706 27081 all phecode
496.3 Bronchiectasis Respiratory 1.03 0.983 – 1.08 0.205 1885 18859 all phecode
497 Bronchitis Respiratory 1 0.921 – 1.09 0.995 626 6267 all phecode
500 Lung disease due to external agents Respiratory 1.03 0.926 – 1.14 0.628 412 4099 all phecode
500.1 Extrinsic allergic alveolitis Respiratory 1.16 0.921 – 1.46 0.209 79 784 all phecode
500.2 Pneumoconiosis Respiratory 0.993 0.869 – 1.13 0.918 243 2409 all phecode
501 Pneumonitis due to inhalation of food or vomitus Respiratory 0.999 0.922 – 1.08 0.989 656 6557 all phecode
502 Postinflammatory pulmonary fibrosis Respiratory 1 0.934 – 1.07 0.994 917 9193 all phecode
503 Pulmonary congestion and hypostasis Respiratory 1.03 0.941 – 1.13 0.512 508 5079 all phecode
504 Other alveolar and parietoalveolar pneumonopathy Respiratory 1.08 0.964 – 1.21 0.187 328 3280 all phecode
505 Other pulmonary inflamation or edema Respiratory 0.85 0.653 – 1.11 0.225 61 610 all phecode
506 Empyema and pneumothorax Respiratory 0.994 0.935 – 1.06 0.842 1133 11362 all phecode
507 Pleurisy; pleural effusion Respiratory 1.02 0.998 – 1.05 0.0678 6419 64252 all phecode
508
Pulmonary collapse; interstitial and
Pulmonary collapse; interstitial and compensatory emphysema
 Respiratory 0.966 0.922 – 1.01 0.138 1996 19947 all phecode
509 Respiratory failure, insufficiency, arrest Respiratory 1.04 1 – 1.09 0.0358 2599 26031 all phecode
509.1 Respiratory failure Respiratory 1.05 1.01 – 1.1 0.0221 2068 20708 all phecode
509.2 Respiratory insufficiency Respiratory 1.03 0.979 – 1.08 0.281 1806 18106 all phecode
509.5 Respiratory arrest Respiratory 0.92 0.777 – 1.09 0.333 143 1429 all phecode
509.8
Dependence on respirator [Ventilator] or
Dependence on respirator [Ventilator] or supplemental oxygen
 Respiratory 1.13 1.02 – 1.26 0.0227 386 3863 all phecode
510 Other diseases of lung Respiratory 1.07 0.99 – 1.15 0.0909 755 7554 all phecode
512 Other symptoms of respiratory system Respiratory 1.04 1.02 – 1.06 0.000217 9031 90349 all phecode
512.1 Wheezing Respiratory 1.03 0.899 – 1.18 0.66 220 2196 all phecode
512.2 Painful respiration Respiratory 1.13 0.983 – 1.3 0.0849 207 2075 all phecode
512.7 Shortness of breath Respiratory 1.06 1.03 – 1.08 9.23e-05 5842 58498 all phecode
512.8 Cough Respiratory 0.998 0.961 – 1.04 0.931 2866 28642 all phecode
512.9 Other dyspnea Respiratory 1.03 0.958 – 1.1 0.473 914 9124 all phecode
513 Respiratory abnormalities Respiratory 1.07 0.986 – 1.16 0.104 611 6112 all phecode
513.3 Hypoventilation Respiratory 1.06 0.849 – 1.33 0.599 83 830 all phecode
513.4 Hyperventilation Respiratory 1.18 1.04 – 1.33 0.00923 278 2778 all phecode
513.8 Disorders of diaphragm Respiratory 1.11 0.938 – 1.31 0.226 153 1538 all phecode
514 Abnormal findings examination of lungs Respiratory 1.01 0.966 – 1.05 0.761 2465 24673 all phecode
516 Abnormal sputum Respiratory 1.03 0.981 – 1.07 0.26 2132 21335 all phecode
516.1 Hemoptysis Respiratory 1.03 0.987 – 1.08 0.168 2073 20745 all phecode
519
Other diseases of respiratory system, not
Other diseases of respiratory system, not elsewhere classified
 Respiratory 1.04 1.02 – 1.06 0.000828 9366 93681 all phecode
519.2 Respiratory complications Respiratory 0.98 0.875 – 1.1 0.727 327 3279 all phecode
519.8 Other diseases of respiratory system, NEC Respiratory 1.04 1.02 – 1.06 0.000432 8853 88522 all phecode
519.9
Symptoms involving respiratory system and other
Symptoms involving respiratory system and other chest symptoms
 Respiratory 0.976 0.868 – 1.1 0.69 303 3049 all phecode
520 Disorders of tooth development Digestive 0.99 0.946 – 1.04 0.659 2038 20354 all phecode
520.1 Hereditary disturbances in tooth structure Digestive 1.06 0.793 – 1.41 0.698 53 530 all phecode
520.2 Disturbances in tooth eruption Digestive 1 0.961 – 1.05 0.899 2356 23539 all phecode
521 Diseases of hard tissues of teeth Digestive 1.05 1.01 – 1.09 0.0124 3016 30245 all phecode
521.1 Dental caries Digestive 1.06 1.02 – 1.1 0.00355 3026 30353 all phecode
522 Diseases of pulp and periapical tissues Digestive 1.01 0.96 – 1.06 0.761 1774 17750 all phecode
522.5 Periapical abscess Digestive 0.998 0.939 – 1.06 0.939 1172 11731 all phecode
523 Gingival and periodontal diseases Digestive 1.01 0.956 – 1.06 0.816 1681 16812 all phecode
523.1 Gingivitis Digestive 1.11 0.914 – 1.35 0.292 113 1127 all phecode
523.3 Periodontitis (acute or chronic) Digestive 0.98 0.923 – 1.04 0.52 1165 11650 all phecode
523.31 Acute periodontitis Digestive 0.999 0.922 – 1.08 0.989 666 6667 all phecode
523.32 Chronic periodontitis Digestive 0.957 0.878 – 1.04 0.321 560 5594 all phecode
524 Dentofacial anomalies, including malocclusion Digestive 1.1 0.979 – 1.23 0.11 331 3307 all phecode
524.3 Anomalies of tooth position/malocclusion Digestive 1.09 0.971 – 1.23 0.141 305 3046 all phecode
525
Other diseases of the teeth and supporting
Other diseases of the teeth and supporting structures
 Digestive 1.03 0.987 – 1.07 0.183 2668 26728 all phecode
525.2 Atrophy of edentulous alveolar ridge Digestive 0.916 0.723 – 1.16 0.471 72 720 all phecode
526 Diseases of the jaws Digestive 0.992 0.927 – 1.06 0.807 928 9279 all phecode
526.1 Cysts of the jaws Digestive 0.97 0.867 – 1.09 0.597 329 3289 all phecode
526.3 Anomalies of jaw size/symmetry Digestive 0.924 0.714 – 1.2 0.55 61 610 all phecode
526.4 Temporomandibular joint disorders Digestive 1.01 0.889 – 1.15 0.853 240 2406 all phecode
526.41 Temporomandibular joint disorder, unspecified Digestive 1.01 0.884 – 1.15 0.911 233 2336 all phecode
526.5 Inflammatory conditions of jaw Digestive 1.06 0.867 – 1.29 0.577 110 1098 all phecode
526.9 Jaw disease NOS Digestive 0.977 0.853 – 1.12 0.733 233 2329 all phecode
527 Diseases of the salivary glands Digestive 1.09 1.01 – 1.18 0.0309 694 6943 all phecode
527.1 Hypertrophy of salivary gland Digestive 1.05 0.849 – 1.31 0.641 84 838 all phecode
527.2 Sialoadenitis Digestive 1.06 0.95 – 1.18 0.3 365 3656 all phecode
527.7 Disturbance of salivary secretion Digestive 0.99 0.769 – 1.27 0.935 62 619 all phecode
527.8 Other specified diseases of the salivary glands Digestive 1.09 0.897 – 1.31 0.399 120 1200 all phecode
528
Diseases of the oral soft tissues, excluding
Diseases of the oral soft tissues, excluding lesions specific for gingiva and tongue
 Digestive 1.04 1 – 1.07 0.0368 3873 38741 all phecode
528.1 Stomatitis and mucositis Digestive 0.992 0.902 – 1.09 0.869 468 4675 all phecode
528.11 Stomatitis and mucositis (ulcerative) Digestive 0.99 0.891 – 1.1 0.844 389 3884 all phecode
528.12 Oral aphthae Digestive 1.05 0.85 – 1.3 0.638 84 840 all phecode
528.3 Cellulitis and abscess of oral soft tissues Digestive 1.06 0.91 – 1.23 0.462 179 1790 all phecode
528.4 Cysts of oral soft tissues Digestive 0.976 0.807 – 1.18 0.804 122 1219 all phecode
528.41 Cyst of the salivary gland Digestive 0.971 0.787 – 1.2 0.787 94 940 all phecode
528.5 Diseases of lips Digestive 0.987 0.914 – 1.07 0.75 681 6813 all phecode
528.6 Leukoplakia of oral mucosa Digestive 1.19 1.06 – 1.33 0.00414 308 3079 all phecode
528.7 Sialolithiasis Digestive 1.05 0.935 – 1.18 0.407 314 3138 all phecode
529 Diseases and other conditions of the tongue Digestive 1 0.943 – 1.06 0.993 1232 12312 all phecode
529.1 Glossitis Digestive 1.05 0.934 – 1.18 0.406 299 2986 all phecode
530 Diseases of esophagus Digestive 1.03 1.02 – 1.04 4.62e-06 33453 279172 all phecode
530.1 Esophagitis, GERD and related diseases Digestive 1.03 1.02 – 1.04 9.99e-07 31253 272429 all phecode
530.11 GERD Digestive 1.03 1.01 – 1.04 0.000175 22633 225879 all phecode
530.12 Ulcer of esophagus Digestive 1.04 1.01 – 1.07 0.0167 5203 52068 all phecode
530.14 Reflux esophagitis Digestive 1.02 1 – 1.05 0.02 10444 104493 all phecode
530.2 Esophageal bleeding (varices/hemorrhage) Digestive 1.04 0.988 – 1.09 0.134 1681 16808 all phecode
530.3 Stricture and stenosis of esophagus Digestive 1.01 0.959 – 1.05 0.809 1869 18684 all phecode
530.5 Disorders of esophageal motility Digestive 0.974 0.899 – 1.06 0.525 635 6365 all phecode
530.6 Diverticulum of esophagus, acquired Digestive 0.946 0.803 – 1.12 0.513 153 1527 all phecode
530.7 Gastroesophageal laceration-hemorrhage syndrome Digestive 0.97 0.867 – 1.08 0.588 341 3416 all phecode
530.9 Heartburn Digestive 1.01 0.968 – 1.06 0.597 2087 20881 all phecode
531 Peptic ulcer (excl. esophageal) Digestive 1.04 1.01 – 1.06 0.00254 7103 71066 all phecode
531.1 Hemorrhage from gastrointestinal ulcer Digestive 0.998 0.92 – 1.08 0.958 637 6374 all phecode
531.2 Gastric ulcer Digestive 1.02 0.991 – 1.06 0.154 4091 40941 all phecode
531.3 Duodenal ulcer Digestive 1.07 1.03 – 1.11 0.000224 2999 30005 all phecode
531.4 Peptic ulcer, site unspecified Digestive 1.04 0.945 – 1.15 0.402 427 4268 all phecode
532 Dysphagia Digestive 1 0.975 – 1.03 0.957 6427 64329 all phecode
535 Gastritis and duodenitis Digestive 1.03 1.02 – 1.05 3.26e-07 28078 261548 all phecode
535.1 Acute gastritis Digestive 1.16 1.09 – 1.23 2.46e-06 1183 11833 all phecode
535.2 Atrophic gastritis Digestive 1 0.902 – 1.12 0.95 370 3687 all phecode
535.6 Duodenitis Digestive 1.04 1.02 – 1.07 0.000685 7592 75928 all phecode
535.8 Other specified gastritis Digestive 1.05 1.03 – 1.08 1.36e-05 8071 80763 all phecode
535.9 Gastritis and duodenitis, NOS Digestive 1.11 0.923 – 1.34 0.267 120 1191 all phecode
536.8
Dyspepsia and other specified disorders of
Dyspepsia and other specified disorders of function of stomach
 Digestive 1.07 0.946 – 1.22 0.273 259 2576 all phecode
537 Other disorders of stomach and duodenum Digestive 1.03 0.995 – 1.07 0.0958 3391 33907 all phecode
540 Appendiceal conditions Digestive 1.01 0.976 – 1.05 0.506 3088 30890 all phecode
540.1 Appendicitis Digestive 1.01 0.975 – 1.05 0.522 2895 28963 all phecode
540.11 Acute appendicitis Digestive 1.01 0.967 – 1.05 0.743 2601 26019 all phecode
550 Abdominal hernia Digestive 1.01 1 – 1.02 0.0198 45429 282640 all phecode
550.1 Inguinal hernia Digestive 0.979 0.963 – 0.996 0.0144 15794 123247 all phecode
550.2 Diaphragmatic hernia Digestive 1.03 1.01 – 1.04 9e-05 26494 238953 all phecode
550.3 Femoral hernia Digestive 0.922 0.849 – 1 0.0531 651 6504 all phecode
550.4 Umbilical hernia Digestive 1.03 0.992 – 1.06 0.129 3705 37072 all phecode
550.5 Ventral hernia Digestive 1 0.965 – 1.04 0.994 3435 34338 all phecode
555
Inflammatory bowel disease and other
Inflammatory bowel disease and other gastroenteritis and colitis
 Digestive 0.997 0.967 – 1.03 0.87 4444 44442 all phecode
555.1 Regional enteritis Digestive 1.04 0.991 – 1.09 0.108 1734 17340 all phecode
555.2 Ulcerative colitis Digestive 0.985 0.95 – 1.02 0.42 3178 31786 all phecode
555.21 Ulcerative colitis (chronic) Digestive 0.942 0.861 – 1.03 0.186 538 5382 all phecode
556 Ulceration of the lower GI tract Digestive 0.999 0.938 – 1.06 0.983 1055 10592 all phecode
556.1 Ulceration of intestine Digestive 1.04 0.958 – 1.12 0.373 670 6714 all phecode
557 Intestinal malabsorption (non-celiac) Digestive 1.11 0.985 – 1.25 0.0871 299 2987 all phecode
557.1 Celiac disease Digestive 1.08 1.03 – 1.13 0.0018 1837 18388 all phecode
558 Noninfectious gastroenteritis Digestive 1.03 1.02 – 1.05 0.000133 15492 155105 all phecode
559 Ileostomy status Digestive 0.974 0.925 – 1.02 0.302 1656 16541 all phecode
560 Intestinal obstruction without mention of hernia Digestive 1.01 0.976 – 1.04 0.624 3936 39337 all phecode
560.1 Paralytic ileus Digestive 1.01 0.925 – 1.11 0.809 523 5231 all phecode
560.2 Impaction of intestine Digestive 1.01 0.895 – 1.15 0.832 268 2671 all phecode
560.3 Peritoneal or intestinal adhesions Digestive 1.01 0.936 – 1.08 0.878 832 8317 all phecode
560.4 Other intestinal obstruction Digestive 1 0.966 – 1.04 0.953 3358 33550 all phecode
561 Symptoms involving digestive system Digestive 1.02 1.01 – 1.04 0.00491 15772 157686 all phecode
561.1 Diarrhea Digestive 1.01 0.916 – 1.11 0.901 466 4653 all phecode
561.2 Flatulence Digestive 1.01 0.956 – 1.06 0.84 1687 16859 all phecode
562 Diverticulosis and diverticulitis Digestive 1.02 1.01 – 1.04 0.000691 26714 211692 all phecode
562.1 Diverticulosis Digestive 1.02 1.01 – 1.04 0.000812 26672 211642 all phecode
563 Constipation Digestive 1.02 1 – 1.05 0.017 10314 103140 all phecode
564 Functional digestive disorders Digestive 1.03 1.02 – 1.05 1.52e-05 21639 209949 all phecode
564.1 Irritable Bowel Syndrome Digestive 1.04 1.01 – 1.07 0.00686 5508 55117 all phecode
564.8
Abnormal findings on exam of gastrointestinal
Abnormal findings on exam of gastrointestinal tract/ abdominal area
 Digestive 1 0.95 – 1.05 0.988 1645 16457 all phecode
564.9 Personal history of diseases of digestive system Digestive 1.04 1.02 – 1.05 2.09e-05 15186 151648 all phecode
565 Anal and rectal conditions Digestive 1.03 1.01 – 1.05 0.000303 14744 147535 all phecode
565.1 Anal and rectal polyp Digestive 1.02 0.999 – 1.05 0.058 7351 73533 all phecode
567 Peritonitis and retroperitoneal infections Digestive 1 0.939 – 1.07 0.895 929 9293 all phecode
568 Other disorders of peritoneum Digestive 1.05 1.01 – 1.08 0.0161 3262 32602 all phecode
568.1
Peritoneal adhesions (postoperative)
Peritoneal adhesions (postoperative) (postinfection)
 Digestive 1.05 1.01 – 1.09 0.0111 3101 30987 all phecode
569 Other disorders of intestine Digestive 1.04 1.01 – 1.07 0.0138 4192 41922 all phecode
569.1 Toxic gastroenteritis and colitis Digestive 0.986 0.835 – 1.16 0.871 148 1479 all phecode
569.2 Gastrointestinal complications Digestive 1.03 0.942 – 1.14 0.481 486 4868 all phecode
571 Chronic liver disease and cirrhosis Digestive 1.1 1.06 – 1.15 3.06e-07 2957 29628 all phecode
571.5 Other chronic nonalcoholic liver disease Digestive 1.16 1.11 – 1.22 4.03e-09 1689 16917 all phecode
571.51 Cirrhosis of liver without mention of alcohol Digestive 1.25 1.04 – 1.51 0.0188 113 1139 all phecode
571.6 Primary biliary cirrhosis Digestive 1.13 0.99 – 1.28 0.0711 257 2568 all phecode
571.8
Liver abscess and sequelae of chronic liver
Liver abscess and sequelae of chronic liver disease
 Digestive 1.04 0.976 – 1.11 0.213 976 9804 all phecode
571.81 Portal hypertension Digestive 1.12 1.02 – 1.22 0.0143 528 5285 all phecode
572 Ascites (non malignant) Digestive 1.1 1.04 – 1.16 0.000621 1544 15454 all phecode
573 Other disorders of liver Digestive 0.986 0.935 – 1.04 0.606 1496 14982 all phecode
573.2 Liver replaced by transplant Digestive 1.2 0.975 – 1.47 0.0854 96 960 all phecode
573.3 Hepatomegaly Digestive 1.08 0.956 – 1.21 0.225 297 2968 all phecode
573.5 Jaundice (not of newborn) Digestive 1.02 0.948 – 1.09 0.666 896 8955 all phecode
573.7 Abnormal results of function study of liver Digestive 1.08 1.04 – 1.11 4.42e-05 3454 34597 all phecode
573.9 Abnormal serum enzyme levels Digestive 0.927 0.802 – 1.07 0.299 209 2089 all phecode
574 Cholelithiasis and cholecystitis Digestive 1.08 1.06 – 1.1 8.74e-19 15607 156123 all phecode
574.1 Cholelithiasis Digestive 1.08 1.06 – 1.1 5.68e-16 13549 135537 all phecode
574.11 Cholelithiasis with acute cholecystitis Digestive 1.05 0.994 – 1.1 0.0816 1506 15072 all phecode
574.12 Cholelithiasis with other cholecystitis Digestive 1.07 1.04 – 1.1 2.99e-06 5429 54289 all phecode
574.2 Calculus of bile duct Digestive 1.05 1.01 – 1.09 0.0156 2620 26191 all phecode
574.3 Cholecystitis without cholelithiasis Digestive 1.09 1.05 – 1.14 7.08e-06 2748 27523 all phecode
575 Other biliary tract disease Digestive 1.05 1.02 – 1.09 0.00302 3867 38724 all phecode
575.1 Cholangitis Digestive 1.06 0.965 – 1.16 0.234 495 4945 all phecode
575.2 Obstruction of bile duct Digestive 1.01 0.937 – 1.08 0.826 774 7756 all phecode
575.6 Cholesterolosis of gallbladder Digestive 1.25 1.14 – 1.38 4.03e-06 458 4577 all phecode
575.7 Other disorders of gallbladder Digestive 1.09 1.03 – 1.15 0.00145 1408 14107 all phecode
575.8 Other disorders of biliary tract Digestive 0.993 0.931 – 1.06 0.829 1036 10367 all phecode
575.9
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of biliary tract
 Digestive 0.93 0.833 – 1.04 0.194 348 3488 all phecode
577 Diseases of pancreas Digestive 1.05 1.01 – 1.1 0.00903 2668 26677 all phecode
577.1 Acute pancreatitis Digestive 1.07 1.02 – 1.12 0.00657 1996 19962 all phecode
577.2 Chronic pancreatitis Digestive 1 0.915 – 1.1 0.943 515 5149 all phecode
577.3 Cyst and pseudocyst of pancreas Digestive 1 0.901 – 1.12 0.952 365 3650 all phecode
578 Gastrointestinal hemorrhage Digestive 1 0.99 – 1.02 0.595 20626 206278 all phecode
578.1 Hematemesis Digestive 1.02 0.979 – 1.07 0.299 1958 19564 all phecode
578.2 Blood in stool Digestive 1.03 0.988 – 1.07 0.174 2626 26283 all phecode
578.8 Hemorrhage of rectum and anus Digestive 1 0.983 – 1.02 0.924 13073 130745 all phecode
578.9 Hemorrhage of gastrointestinal tract Digestive 0.993 0.965 – 1.02 0.622 5275 52787 all phecode
579 Other symptoms involving abdomen and pelvis Digestive 1 0.951 – 1.06 0.932 1548 15498 all phecode
579.2 Splenomegaly Digestive 1.03 0.931 – 1.14 0.56 422 4246 all phecode
579.8 Nonspecific abnormal findings in stool contents Digestive 1.01 0.957 – 1.06 0.799 1654 16540 all phecode
580 Nephritis; nephrosis; renal sclerosis Genitourinary 1.13 1.08 – 1.19 3.02e-06 1531 15350 all phecode
580.1 Glomerulonephritis Genitourinary 1.12 1.05 – 1.19 0.000642 1052 10544 all phecode
580.11 Proliferative glomerulonephritis Genitourinary 1.05 0.838 – 1.32 0.655 74 738 all phecode
580.12 Non-proliferative glomerulonephritis Genitourinary 1.13 0.946 – 1.34 0.18 135 1360 all phecode
580.14 Chronic glomerulonephritis, NOS Genitourinary 1.1 1.03 – 1.18 0.00678 876 8769 all phecode
580.2
Nephrotic syndrome without mention of
Nephrotic syndrome without mention of glomerulonephritis
 Genitourinary 1.23 1.12 – 1.36 1.31e-05 468 4697 all phecode
580.3
Nephritis and nephropathy without mention of
Nephritis and nephropathy without mention of glomerulonephritis
 Genitourinary 1.14 1 – 1.3 0.0461 246 2460 all phecode
580.32
Nephritis and nephropathy with pathological
Nephritis and nephropathy with pathological lesion
 Genitourinary 1.12 0.987 – 1.28 0.0789 253 2529 all phecode
585 Renal failure Genitourinary 1.07 1.05 – 1.1 1.7e-08 6967 69751 all phecode
585.1 Acute renal failure Genitourinary 1.09 1.05 – 1.12 1.01e-07 4527 45305 all phecode
585.2 Renal failure NOS Genitourinary 1.04 0.985 – 1.1 0.157 1460 14625 all phecode
585.3 Chronic renal failure [CKD] Genitourinary 1.11 1.06 – 1.15 6.66e-07 2644 26484 all phecode
585.31 Renal dialysis Genitourinary 1.03 0.937 – 1.13 0.561 496 4955 all phecode
586 Other disorders of the kidney and ureters Genitourinary 1.04 1 – 1.07 0.0491 3355 33580 all phecode
586.1 Anatomical abnormatilies of kidney and ureters Genitourinary 1.04 0.901 – 1.2 0.604 208 2089 all phecode
586.11 Small kidney Genitourinary 1.04 0.888 – 1.21 0.658 179 1799 all phecode
586.2 Cyst of kidney, acquired Genitourinary 1.03 0.971 – 1.09 0.334 1257 12582 all phecode
586.3 Vascular disorders of kidney/hypertrophy Genitourinary 1.17 0.933 – 1.47 0.172 80 799 all phecode
586.4 Stricture/obstruction of ureter Genitourinary 0.993 0.928 – 1.06 0.836 910 9122 all phecode
587 Kidney replaced by transpant Genitourinary 0.966 0.868 – 1.08 0.533 368 3683 all phecode
588 Disorders resulting from impaired renal function Genitourinary 0.986 0.804 – 1.21 0.893 99 990 all phecode
589 Abnormal results of function study of kidney Genitourinary 1.02 0.843 – 1.23 0.842 116 1158 all phecode
590 Pyelonephritis Genitourinary 1.06 1 – 1.12 0.0521 1328 13285 all phecode
591 Urinary tract infection Genitourinary 1.01 0.995 – 1.03 0.155 12400 123937 all phecode
592 Cystitis and urethritis Genitourinary 1.04 0.997 – 1.08 0.0685 2966 29661 all phecode
592.1 Cystitis Genitourinary 1.03 0.992 – 1.07 0.123 2904 29035 all phecode
592.11 Acute cystitis Genitourinary 1 0.849 – 1.19 0.958 138 1372 all phecode
592.12 Chronic cystitis Genitourinary 1.04 0.968 – 1.11 0.303 889 8890 all phecode
592.13 Chronic interstitial cystitis Genitourinary 1.02 0.894 – 1.16 0.768 249 2486 all phecode
592.2 Urethritis and urethral syndrome Genitourinary 1.21 1.03 – 1.42 0.02 165 1662 all phecode
593 Hematuria Genitourinary 1.02 1.01 – 1.04 0.00845 16068 160204 all phecode
594 Urinary calculus Genitourinary 1.07 1.04 – 1.1 2.37e-07 6376 63761 all phecode
594.1 Calculus of kidney Genitourinary 1.06 1.02 – 1.1 0.0016 3175 31757 all phecode
594.2 Calculus of lower urinary tract Genitourinary 1.01 0.939 – 1.09 0.74 776 7764 all phecode
594.3 Calculus of ureter Genitourinary 1.07 1.02 – 1.11 0.00276 2401 24024 all phecode
594.8 Renal colic Genitourinary 1.13 1.08 – 1.18 2.61e-07 2050 20500 all phecode
595 Hydronephrosis Genitourinary 1.04 0.993 – 1.09 0.0952 1936 19395 all phecode
596 Other disorders of bladder Genitourinary 1.01 0.988 – 1.03 0.397 9771 97778 all phecode
596.1 Bladder neck obstruction Genitourinary 1.02 0.978 – 1.07 0.314 1969 19690 all phecode
596.5 Functional disorders of bladder Genitourinary 0.979 0.931 – 1.03 0.423 1658 16572 all phecode
597 Other disorders of urethra and urinary tract Genitourinary 1.02 0.988 – 1.06 0.219 3913 39135 all phecode
597.1 Urethral stricture (not specified as infectious) Genitourinary 1.02 0.987 – 1.06 0.211 3317 33137 all phecode
597.2 Urinary complications NEC Genitourinary 1.03 0.808 – 1.3 0.834 78 778 all phecode
598 Abnormal findings on examination of urine Genitourinary 0.991 0.958 – 1.03 0.627 3528 35302 all phecode
598.9
Other nonspecific findings on examination of
Other nonspecific findings on examination of urine
 Genitourinary 0.932 0.829 – 1.05 0.237 304 3035 all phecode
599 Other symptoms/disorders or the urinary system Genitourinary 1.03 1.02 – 1.05 2.46e-05 18428 184311 all phecode
599.1 Urinary obstruction Genitourinary 0.983 0.84 – 1.15 0.833 166 1670 all phecode
599.2 Retention of urine Genitourinary 1.01 0.986 – 1.04 0.402 6718 67168 all phecode
599.3 Dysuria Genitourinary 1.01 0.95 – 1.07 0.784 1196 11967 all phecode
599.4 Urinary incontinence Genitourinary 1.06 1.03 – 1.08 1.04e-06 8748 87477 all phecode
599.5 Frequency of urination and polyuria Genitourinary 1.03 0.994 – 1.06 0.116 4018 40144 all phecode
599.6 Oliguria and anuria Genitourinary 1.01 0.828 – 1.24 0.895 105 1059 all phecode
599.8 Other symptoms involving urinary system Genitourinary 0.98 0.758 – 1.27 0.88 62 620 all phecode
599.9 Other abnormality of urination Genitourinary 1 0.957 – 1.05 0.907 1913 19151 all phecode
600 Hyperplasia of prostate Genitourinary 0.999 0.979 – 1.02 0.897 11093 87892 all phecode
601 Inflammatory diseases of prostate Genitourinary 1.04 0.991 – 1.08 0.113 2081 20818 all phecode
601.1 Prostatitis Genitourinary 1.03 0.978 – 1.09 0.254 1563 15644 all phecode
601.11 Acute prostatitis Genitourinary 0.979 0.855 – 1.12 0.76 234 2358 all phecode
601.12 Chronic prostatitis Genitourinary 0.993 0.928 – 1.06 0.842 910 9089 all phecode
601.3 Orchitis and epididymitis Genitourinary 0.828 0.64 – 1.07 0.148 59 588 all phecode
601.4 Balanoposthitis Genitourinary 1.08 0.958 – 1.22 0.208 287 2864 all phecode
601.8
Other inflammatory disorders of male genital
Other inflammatory disorders of male genital organs
 Genitourinary 1.06 0.948 – 1.2 0.292 303 3019 all phecode
602 Other disorders of prostate Genitourinary 1.06 1.01 – 1.13 0.0303 1341 13408 all phecode
603 Other disorders of testis Genitourinary 1.06 1.02 – 1.11 0.00746 2150 21512 all phecode
603.1 Hydrocele Genitourinary 1.05 0.991 – 1.11 0.0989 1339 13402 all phecode
604 Disorders of penis Genitourinary 1.09 1.05 – 1.13 4.61e-06 3280 32779 all phecode
604.1 Redundant prepuce and phimosis/BXO Genitourinary 1.08 1.04 – 1.12 0.000172 2719 27172 all phecode
605 Erectile dysfunction [ED] Genitourinary 1.08 0.956 – 1.22 0.217 278 2800 all phecode
608 Other disorders of male genital organs Genitourinary 0.979 0.942 – 1.02 0.293 2822 28236 all phecode
609 Male infertility and abnormal spermatozoa Genitourinary 0.97 0.841 – 1.12 0.673 214 2138 all phecode
609.1 Infertility, male Genitourinary 0.909 0.704 – 1.17 0.466 63 638 all phecode
609.2 Abnormal spermatozoa Genitourinary 0.999 0.85 – 1.17 0.988 169 1698 all phecode
610 Benign mammary dysplasias Genitourinary 0.979 0.939 – 1.02 0.305 2482 24809 all phecode
610.1 Cystic mastopathy Genitourinary 0.946 0.884 – 1.01 0.109 925 9250 all phecode
610.2 Fibroadenosis of breast Genitourinary 1.06 0.941 – 1.19 0.347 306 3057 all phecode
610.3 Fibrosclerosis of breast Genitourinary 1.05 0.933 – 1.19 0.399 302 3018 all phecode
610.4 Benign neoplasm of breast Genitourinary 0.974 0.921 – 1.03 0.353 1388 13865 all phecode
610.8 Other specified benign mammary dysplasias Genitourinary 1.04 0.96 – 1.12 0.347 696 6954 all phecode
611 Abnormal findings on mammogram or breast exam Genitourinary 0.968 0.919 – 1.02 0.215 1574 15731 all phecode
611.1 Abnormal mammogram Genitourinary 1.05 0.802 – 1.37 0.736 57 569 all phecode
611.3 Lump or mass in breast Genitourinary 0.967 0.917 – 1.02 0.212 1522 15213 all phecode
612
Breast conditions, congenital or relating to
Breast conditions, congenital or relating to hormones
 Genitourinary 1.08 1.01 – 1.16 0.0224 887 8871 all phecode
612.2 Hypertrophy of breast (Gynecomastia) Genitourinary 1.07 0.998 – 1.15 0.0565 849 8490 all phecode
612.3 Congenital anomalies of breast Genitourinary 1.17 0.935 – 1.46 0.171 72 719 all phecode
613 Other nonmalignant breast conditions Genitourinary 1.04 0.987 – 1.09 0.148 1651 16519 all phecode
613.1 Inflammatory disease of breast Genitourinary 1.05 0.976 – 1.14 0.177 720 7210 all phecode
613.5 Mastodynia Genitourinary 1.03 0.821 – 1.3 0.774 77 768 all phecode
613.7 Other signs and symptoms in breast Genitourinary 1.04 0.958 – 1.12 0.373 702 7013 all phecode
613.8 Other specified disorders of breast Genitourinary 0.996 0.89 – 1.11 0.938 327 3278 all phecode
613.9 Breast disorder NOS Genitourinary 0.972 0.846 – 1.12 0.687 207 2069 all phecode
614 Inflammatory diseases of female pelvic organs Genitourinary 1.04 1.01 – 1.07 0.00325 5711 57118 all phecode
614.1
Pelvic peritoneal adhesions, female
Pelvic peritoneal adhesions, female (postoperative) (postinfection)
 Genitourinary 1.04 0.997 – 1.08 0.0696 2538 25363 all phecode
614.3 Pelvic inflammatory disease (PID) Genitourinary 1.07 1 – 1.15 0.051 830 8308 all phecode
614.31 Acute inflammatory pelvic disease Genitourinary 1.13 0.867 – 1.47 0.368 61 608 all phecode
614.32 Chronic inflammatory pelvic disease Genitourinary 1.09 0.986 – 1.21 0.093 422 4221 all phecode
614.33 Pelvic inflammatory disease, NOS Genitourinary 1.07 0.959 – 1.19 0.225 351 3510 all phecode
614.4 Inflammatory diseases of uterus, except cervix Genitourinary 1.13 0.996 – 1.27 0.0583 277 2775 all phecode
614.5
Inflammatory disease of cervix, vagina, and
Inflammatory disease of cervix, vagina, and vulva
 Genitourinary 1.04 0.998 – 1.08 0.0627 2601 26023 all phecode
614.51 Cervicitis and endocervicitis Genitourinary 1.02 0.963 – 1.08 0.516 1318 13189 all phecode
614.52 Vaginitis and vulvovaginitis Genitourinary 0.997 0.902 – 1.1 0.951 428 4273 all phecode
614.53 Cyst or abscess of Bartholin's gland Genitourinary 1.03 0.953 – 1.11 0.489 755 7574 all phecode
614.54 Abscess or ulceration of vulva Genitourinary 1.09 0.957 – 1.23 0.199 274 2737 all phecode
615 Endometriosis Genitourinary 1.05 1.01 – 1.08 0.00692 4029 40284 all phecode
617
Disorders secondary to childbirth, surgery
Disorders secondary to childbirth, surgery, trauma
 Genitourinary 1.11 0.988 – 1.25 0.0791 304 3037 all phecode
618 Genital prolapse Genitourinary 1.03 1.01 – 1.05 0.00838 11689 116878 all phecode
618.1 Prolapse of vaginal walls Genitourinary 1.03 1 – 1.05 0.0337 7392 73940 all phecode
618.2 Uterine/Uterovaginal prolapse Genitourinary 1.03 1 – 1.06 0.0335 5393 53918 all phecode
618.5 Prolapse of vaginal vault after hysterectomy Genitourinary 1.04 0.947 – 1.14 0.413 512 5125 all phecode
618.6 Vaginal enterocele, congenital or acquired Genitourinary 0.996 0.919 – 1.08 0.916 680 6794 all phecode
619 Noninflammatory female genital disorders Genitourinary 1.03 1.01 – 1.05 0.0128 8726 87297 all phecode
619.1
Noninflammatory disorders of ovary, fallopian
Noninflammatory disorders of ovary, fallopian tube, and broad ligament
 Genitourinary 0.993 0.92 – 1.07 0.866 729 7284 all phecode
619.2 Disorders of uterus, NEC Genitourinary 1.03 0.991 – 1.06 0.141 3324 33273 all phecode
619.3 Noninflammatory disorders of cervix Genitourinary 1.06 1.02 – 1.1 0.00342 2860 28608 all phecode
619.4 Noninflammatory disorders of vagina Genitourinary 0.977 0.931 – 1.03 0.358 1768 17669 all phecode
619.5 Noninflammatory disorders of vulva and perineum Genitourinary 1.01 0.957 – 1.07 0.67 1350 13489 all phecode
620 Dysplasia of female genital organs Genitourinary 0.921 0.729 – 1.16 0.488 72 720 all phecode
621 Endometrial hyperplasia Genitourinary 1.08 1.02 – 1.15 0.0117 1129 11294 all phecode
622 Polyp of female genital organs Genitourinary 1.02 1 – 1.04 0.0269 10480 104803 all phecode
622.1 Polyp of corpus uteri Genitourinary 1.03 1.01 – 1.05 0.0162 7857 78601 all phecode
622.2 Mucous polyp of cervix Genitourinary 1.02 0.984 – 1.06 0.287 3442 34387 all phecode
623 Hypertrophy of female genital organs Genitourinary 1.02 0.967 – 1.09 0.409 1268 12684 all phecode
624 Symptoms involving female genital tract Genitourinary 1.06 0.984 – 1.14 0.125 797 7961 all phecode
624.1 Dystrophy of female genital tract Genitourinary 1.01 0.886 – 1.15 0.877 237 2365 all phecode
624.2 Atrophy of female genital tract Genitourinary 1.08 0.983 – 1.2 0.106 440 4398 all phecode
624.9 stress incontinence, female Genitourinary 1.08 1.05 – 1.11 2.51e-08 5865 58634 all phecode
625
Pain and other symptoms associated with female
Pain and other symptoms associated with female genital organs
 Genitourinary 1.02 0.985 – 1.06 0.232 2876 28740 all phecode
625.1 Dyspareunia Genitourinary 1.03 0.969 – 1.09 0.345 1188 11891 all phecode
626
Disorders of menstruation and other abnormal
Disorders of menstruation and other abnormal bleeding from female genital tract
 Genitourinary 1.04 1.02 – 1.06 3.99e-06 16168 115018 all phecode
626.1 Irregular menstrual cycle/bleeding Genitourinary 1.04 1.03 – 1.06 1.28e-06 14110 109918 all phecode
626.11 Absent or infrequent menstruation Genitourinary 1.02 0.833 – 1.24 0.866 109 1099 all phecode
626.12 Excessive or frequent menstruation Genitourinary 1.06 1.04 – 1.08 8.88e-08 9727 91749 all phecode
626.13 Irregular menstrual cycle Genitourinary 1.02 0.976 – 1.07 0.365 1985 19829 all phecode
626.14 Irregular menstrual bleeding Genitourinary 1.04 1.01 – 1.08 0.0107 3804 38021 all phecode
626.2 Dysmenorrhea Genitourinary 1.07 1.02 – 1.13 0.00405 1778 17767 all phecode
626.4 Premenstrual tension syndromes Genitourinary 1.03 0.874 – 1.21 0.736 159 1587 all phecode
626.8 Infertility, female Genitourinary 0.983 0.929 – 1.04 0.548 1362 13613 all phecode
627 Menopausal and postmenopausal disorders Genitourinary 1.05 1.02 – 1.07 1.85e-05 10392 103948 all phecode
627.1 Postmenopausal bleeding Genitourinary 1.05 1.02 – 1.07 3.31e-05 9042 90439 all phecode
627.2 Symptomatic menopause Genitourinary 1 0.862 – 1.17 0.973 183 1826 all phecode
627.3 Postmenopausal atrophic vaginitis Genitourinary 1.02 0.955 – 1.08 0.624 1111 11115 all phecode
627.4 Premenopausal menorrhagia Genitourinary 1.06 0.943 – 1.19 0.322 310 3097 all phecode
628 Ovarian cyst Genitourinary 1.05 1.02 – 1.08 0.000972 4747 47482 all phecode
634 Miscarriage; stillbirth Pregnancy Complications 0.983 0.955 – 1.01 0.249 5218 36422 all phecode
634.1 Missed abortion/Hydatidiform mole Pregnancy Complications 0.956 0.899 – 1.02 0.147 1136 11300 all phecode
634.3 Ectopic pregnancy Pregnancy Complications 1.02 0.91 – 1.14 0.733 331 3305 all phecode
635
Hemorrhage during pregnancy; childbirth and
Hemorrhage during pregnancy; childbirth and postpartum
 Pregnancy Complications 0.967 0.923 – 1.01 0.157 1974 17372 all phecode
635.2
Antepartum hemorrhage, abruptio placentae, and
Antepartum hemorrhage, abruptio placentae, and placenta previa
 Pregnancy Complications 0.959 0.895 – 1.03 0.238 866 8614 all phecode
635.3 Placenta previa and abruptio placenta Pregnancy Complications 0.961 0.907 – 1.02 0.185 1270 12306 all phecode
636
Early or threatened labor; hemorrhage in early
Early or threatened labor; hemorrhage in early pregnancy
 Pregnancy Complications 0.994 0.952 – 1.04 0.777 2347 19972 all phecode
636.2 Early onset of delivery Pregnancy Complications 0.974 0.897 – 1.06 0.525 617 6144 all phecode
636.3 Hemorrhage in early pregnancy Pregnancy Complications 0.963 0.904 – 1.03 0.244 1082 10766 all phecode
638 Other high-risk pregnancy Pregnancy Complications 0.807 0.635 – 1.03 0.08 70 700 all phecode
642
Hypertension complicating pregnancy
Hypertension complicating pregnancy, childbirth, and the puerperium
 Pregnancy Complications 1.02 0.96 – 1.09 0.499 1110 11074 all phecode
642.1 Preeclampsia and eclampsia Pregnancy Complications 1.1 0.982 – 1.24 0.0996 307 3058 all phecode
643 Excessive vomiting in pregnancy Pregnancy Complications 1 0.875 – 1.15 0.957 215 2149 all phecode
643.1 Hyperemesis gravidarum Pregnancy Complications 0.953 0.81 – 1.12 0.562 153 1525 all phecode
645 Late pregnancy and failed induction Pregnancy Complications 0.947 0.894 – 1 0.0668 1250 12450 all phecode
646 Other complications of pregnancy NEC Pregnancy Complications 0.978 0.936 – 1.02 0.324 2228 20847 all phecode
647
Infectious and parasitic complications
Infectious and parasitic complications affecting pregnancy
 Pregnancy Complications 1.2 0.936 – 1.53 0.152 68 679 all phecode
647.1
Infections of genitourinary tract during
Infections of genitourinary tract during pregnancy
 Pregnancy Complications 1.04 0.924 – 1.18 0.493 275 2748 all phecode
649
Other conditions or status of the mother
Other conditions or status of the mother complicating pregnancy, childbirth, or the puerperium
 Pregnancy Complications 0.8 0.66 – 0.969 0.0228 113 1129 all phecode
649.1
Diabetes or abnormal glucose tolerance
Diabetes or abnormal glucose tolerance complicating pregnancy
 Pregnancy Complications 1.31 1.13 – 1.52 0.000372 193 1922 all phecode
650 Normal delivery Pregnancy Complications 0.975 0.93 – 1.02 0.289 1922 18973 all phecode
651 Multiple gestation Pregnancy Complications 0.953 0.853 – 1.06 0.393 346 3454 all phecode
652
Malposition and malpresentation of fetus or
Malposition and malpresentation of fetus or obstruction
 Pregnancy Complications 1 0.951 – 1.05 0.997 1716 16521 all phecode
653
Problems associated with amniotic cavity and
Problems associated with amniotic cavity and membranes
 Pregnancy Complications 1.01 0.957 – 1.07 0.693 1401 13649 all phecode
654
Other and unspecified complications of birth
Other and unspecified complications of birth; puerperium affecting management of mother
 Pregnancy Complications 0.818 0.645 – 1.04 0.0958 74 739 all phecode
655
Known or suspected fetal abnormality affecting
Known or suspected fetal abnormality affecting management of mother
 Pregnancy Complications 0.98 0.949 – 1.01 0.217 4306 29454 all phecode
656 Other perinatal conditions of fetus or newborn Pregnancy Complications 1.06 0.874 – 1.29 0.553 109 1080 all phecode
661 Fetal distress and abnormal forces of labor Pregnancy Complications 0.969 0.927 – 1.01 0.163 2265 18397 all phecode
663
Umbilical cord complications during labor and
Umbilical cord complications during labor and delivery
 Pregnancy Complications 1.03 0.947 – 1.13 0.455 532 5316 all phecode
665 Obstetrical/birth trauma Pregnancy Complications 0.954 0.926 – 0.983 0.00205 5313 29472 all phecode
669 Complications of labor and delivery NEC Pregnancy Complications 0.953 0.915 – 0.993 0.0231 2552 21174 all phecode
671
Venous/cerebrovascular complications embolism
Venous/cerebrovascular complications embolism in pregnancy and the puerperium
 Pregnancy Complications 0.958 0.819 – 1.12 0.588 164 1628 all phecode
674 Other complications of the puerperium NEC Pregnancy Complications 1.03 0.909 – 1.17 0.624 262 2605 all phecode
676
Other disorders of the breast associated with
Other disorders of the breast associated with childbirth and disorders of lactation
 Pregnancy Complications 1.13 0.883 – 1.45 0.329 63 624 all phecode
679 Complications of in utero procedures Dermatologic 0.881 0.667 – 1.16 0.37 53 530 all phecode
681 Superficial cellulitis and abscess Dermatologic 1.05 1.03 – 1.08 2.19e-05 7200 72225 all phecode
681.1 Cellulitis and abscess of fingers/toes Dermatologic 1.06 0.974 – 1.16 0.17 563 5647 all phecode
681.2 Cellulitis and abscess of face/neck Dermatologic 1.04 0.947 – 1.13 0.446 520 5208 all phecode
681.3 Cellulitis and abscess of arm/hand Dermatologic 1.05 1.02 – 1.08 0.000279 5481 55014 all phecode
681.5 Cellulitis and abscess of leg, except foot Dermatologic 1.05 1.02 – 1.08 0.000242 5487 55074 all phecode
681.6 Cellulitis and abscess of foot, toe Dermatologic 1.05 1.02 – 1.08 0.000316 5444 54643 all phecode
681.7 Cellulitis and abscess of trunk Dermatologic 1.08 0.993 – 1.17 0.0729 597 5987 all phecode
686
Other local infections of skin and subcutaneous
Other local infections of skin and subcutaneous tissue
 Dermatologic 1.03 0.975 – 1.09 0.276 1337 13427 all phecode
686.1 Carbuncle and furuncle Dermatologic 1.07 1.03 – 1.12 0.00139 2284 22925 all phecode
686.3 Pilonidal cyst Dermatologic 1.05 0.969 – 1.15 0.219 583 5837 all phecode
686.4 Pyogenic granuloma Dermatologic 1.05 0.942 – 1.16 0.394 362 3615 all phecode
687 Symptoms affecting skin Dermatologic 1.02 0.933 – 1.11 0.67 548 5508 all phecode
687.1 Rash and other nonspecific skin eruption Dermatologic 1.01 0.968 – 1.06 0.614 2146 21470 all phecode
687.2 Localized superficial swelling, mass, or lump Dermatologic 1.08 0.96 – 1.22 0.192 283 2839 all phecode
687.3 Changes in skin texture Dermatologic 0.9 0.738 – 1.1 0.301 106 1070 all phecode
687.4 Disturbance of skin sensation Dermatologic 1.01 0.974 – 1.05 0.527 2884 28859 all phecode
689 Disorder of skin and subcutaneous tissue NOS Dermatologic 1.01 0.98 – 1.03 0.634 5747 57521 all phecode
690 Erythematosquamous dermatosis Dermatologic 1.12 0.873 – 1.43 0.378 71 710 all phecode
690.1 Seborrheic dermatitis Dermatologic 1.03 0.771 – 1.38 0.838 53 530 all phecode
691 Congenital anomalies of skin Dermatologic 0.968 0.803 – 1.17 0.73 120 1199 all phecode
694 Dyschromia and Vitiligo Dermatologic 1 0.939 – 1.07 0.967 986 9854 all phecode
694.1 Vitiligo Dermatologic 0.968 0.747 – 1.25 0.805 60 599 all phecode
694.2 Other dyschromia Dermatologic 1 0.931 – 1.08 0.96 782 7821 all phecode
694.3 Vascular disorders of skin Dermatologic 0.936 0.781 – 1.12 0.478 117 1170 all phecode
695 Erythematous conditions Dermatologic 1.02 0.975 – 1.06 0.439 2379 23813 all phecode
695.1 Toxic erythema Dermatologic 1.17 0.961 – 1.41 0.12 109 1090 all phecode
695.2 Bullous dermatoses Dermatologic 0.94 0.791 – 1.12 0.486 137 1365 all phecode
695.21 Dermatitis herpetiformis Dermatologic 0.946 0.729 – 1.23 0.677 57 569 all phecode
695.22 Pemphigus and pemphigoid Dermatologic 0.872 0.688 – 1.11 0.259 73 727 all phecode
695.3 Rosacea Dermatologic 1.03 0.918 – 1.16 0.587 309 3097 all phecode
695.4 Lupus (localized and systemic) Dermatologic 0.973 0.878 – 1.08 0.604 411 4114 all phecode
695.41 Cutaneous lupus erythematosus Dermatologic 0.923 0.77 – 1.11 0.382 130 1295 all phecode
695.42 Systemic lupus erythematosus Dermatologic 0.964 0.862 – 1.08 0.525 340 3407 all phecode
695.7 Prurigo and Lichen Dermatologic 1.04 0.966 – 1.12 0.294 775 7760 all phecode
695.8 Other specified erythematous conditions Dermatologic 1.14 0.995 – 1.3 0.0585 236 2359 all phecode
695.81 Erythema nodosum Dermatologic 1.16 0.918 – 1.47 0.212 76 760 all phecode
695.9 Unspecified erythematous condition Dermatologic 0.958 0.871 – 1.05 0.385 467 4672 all phecode
696 Psoriasis and related disorders Dermatologic 1.06 1.01 – 1.11 0.00971 2252 22509 all phecode
696.4 Psoriasis Dermatologic 1.06 1.01 – 1.11 0.00923 2198 21969 all phecode
696.41 Psoriasis vulgaris Dermatologic 1.05 1 – 1.11 0.04 1680 16796 all phecode
696.42 Psoriatic arthropathy Dermatologic 1.06 0.984 – 1.15 0.122 706 7052 all phecode
697 Sarcoidosis Dermatologic 1.1 1.01 – 1.21 0.0272 539 5373 all phecode
698 Pruritus and related conditions Dermatologic 0.998 0.927 – 1.07 0.962 782 7814 all phecode
700 Corns and callosities Dermatologic 0.969 0.86 – 1.09 0.611 291 2904 all phecode
701
Other hypertrophic and atrophic conditions of
Other hypertrophic and atrophic conditions of skin
 Dermatologic 1.01 0.984 – 1.04 0.37 4663 46650 all phecode
701.1 Keratoderma, acquired Dermatologic 0.962 0.775 – 1.19 0.724 87 870 all phecode
701.2 Scar conditions and fibrosis of skin Dermatologic 1 0.958 – 1.04 0.996 2348 23478 all phecode
701.3 Circumscribed scleroderma Dermatologic 1.23 0.947 – 1.59 0.121 61 610 all phecode
701.4 Keloid scar Dermatologic 1.05 0.907 – 1.2 0.541 216 2159 all phecode
701.5 Abnormal granulation tissue Dermatologic 0.966 0.877 – 1.06 0.487 455 4568 all phecode
701.6 Acquired acanthosis nigricans Dermatologic 0.981 0.8 – 1.2 0.85 102 1019 all phecode
702
Degenerative skin conditions and other
Degenerative skin conditions and other dermatoses
 Dermatologic 1.02 0.987 – 1.04 0.294 5459 54587 all phecode
702.1 Actinic keratosis Dermatologic 1.01 0.974 – 1.06 0.501 2585 25842 all phecode
702.2 Seborrheic keratosis Dermatologic 1.01 0.975 – 1.05 0.53 3078 30772 all phecode
703 Diseases of nail, NOS Dermatologic 1.03 0.924 – 1.15 0.592 354 3539 all phecode
703.1 Ingrowing nail Dermatologic 1.02 0.949 – 1.09 0.66 966 9660 all phecode
704 Diseases of hair and hair follicles Dermatologic 1.01 0.98 – 1.04 0.563 5267 52727 all phecode
704.1 Alopecia Dermatologic 1.05 0.879 – 1.26 0.567 125 1269 all phecode
704.8
Other specified diseases of hair and hair
Other specified diseases of hair and hair follicles
 Dermatologic 1.08 0.856 – 1.37 0.503 76 759 all phecode
705 Disorders of sweat glands Dermatologic 1.04 0.904 – 1.19 0.614 228 2287 all phecode
705.3 Hidradenitis Dermatologic 1.07 0.92 – 1.24 0.39 186 1868 all phecode
705.8 Hyperhidrosis Dermatologic 1.06 0.976 – 1.16 0.161 591 5919 all phecode
706 Diseases of sebaceous glands Dermatologic 1.01 0.991 – 1.04 0.231 8317 83195 all phecode
706.1 Acne Dermatologic 0.977 0.78 – 1.22 0.836 78 779 all phecode
706.2 Sebaceous cyst Dermatologic 1.02 0.998 – 1.04 0.0815 8787 87882 all phecode
707 Chronic ulcer of skin Dermatologic 1.09 1.04 – 1.14 0.000226 1953 19654 all phecode
707.1 Decubitus ulcer Dermatologic 1.04 0.974 – 1.12 0.232 909 9097 all phecode
709 Diffuse diseases of connective tissue Dermatologic 1.04 1.01 – 1.08 0.0202 3432 34317 all phecode
709.2 Sicca syndrome Dermatologic 1.06 0.964 – 1.16 0.246 508 5073 all phecode
709.3 Systemic sclerosis Dermatologic 1.01 0.866 – 1.18 0.891 176 1753 all phecode
709.6
Other specified diffuse diseases of connective
Other specified diffuse diseases of connective tissue
 Dermatologic 1.17 0.913 – 1.51 0.211 65 649 all phecode
709.7 Unspecified diffuse connective tissue disease Dermatologic 1.05 1.01 – 1.09 0.0162 2714 27144 all phecode
710
Osteomyelitis, periostitis, and other
Osteomyelitis, periostitis, and other infections involving bone
 Musculoskeletal 1.17 1.07 – 1.27 0.000308 602 6034 all phecode
710.1 Osteomyelitis Musculoskeletal 1.22 1.12 – 1.33 9.8e-06 556 5574 all phecode
710.12 Chronic osteomyelitis Musculoskeletal 1.3 1.13 – 1.51 0.000412 194 1947 all phecode
710.19 Unspecified osteomyelitis Musculoskeletal 1.2 1.09 – 1.33 0.000418 398 3997 all phecode
711 Arthropathy associated with infections Musculoskeletal 1.01 0.912 – 1.12 0.863 421 4225 all phecode
711.1 Pyogenic arthritis Musculoskeletal 1.03 0.919 – 1.16 0.609 328 3296 all phecode
712 Infective connective tissue disorders Musculoskeletal 0.937 0.738 – 1.19 0.596 81 810 all phecode
713
Arthropathy associated with other disorders
Arthropathy associated with other disorders classified elsewhere
 Musculoskeletal 1.24 1.05 – 1.46 0.0133 148 1499 all phecode
713.5
Arthropathy associated with neurological
Arthropathy associated with neurological disorders
 Musculoskeletal 1.71 1.33 – 2.2 2.87e-05 65 669 all phecode
714
Rheumatoid arthritis and other inflammatory
Rheumatoid arthritis and other inflammatory polyarthropathies
 Musculoskeletal 1.06 1.03 – 1.09 5.96e-05 4832 48320 all phecode
714.1 Rheumatoid arthritis Musculoskeletal 1.06 1.03 – 1.1 9.08e-05 4372 43714 all phecode
715 Other inflammatory spondylopathies Musculoskeletal 1.07 1.02 – 1.12 0.00864 1659 16588 all phecode
715.1 Sacroiliitis NEC Musculoskeletal 1.09 0.906 – 1.32 0.355 113 1129 all phecode
715.2 Ankylosing spondylitis Musculoskeletal 1.1 1.02 – 1.2 0.0205 618 6177 all phecode
716 Other arthropathies Musculoskeletal 1.04 1.03 – 1.05 6.71e-14 37478 265375 all phecode
716.1 Unspecified polyarthropathy or polyarthritis Musculoskeletal 1.06 1.02 – 1.1 0.00118 3505 35090 all phecode
716.2 Unspecified monoarthritis Musculoskeletal 1.04 1.02 – 1.06 6.33e-06 15522 155339 all phecode
716.9 Arthropathy NOS Musculoskeletal 1.04 1.03 – 1.05 2.35e-13 35944 262308 all phecode
717 Polymyalgia Rheumatica Musculoskeletal 1.03 0.971 – 1.1 0.312 1145 11480 all phecode
720 Spinal stenosis Musculoskeletal 1.03 0.995 – 1.06 0.0903 3705 37091 all phecode
721 Spondylosis and allied disorders Musculoskeletal 1.03 1.01 – 1.05 0.0122 7832 78318 all phecode
721.1 Spondylosis without myelopathy Musculoskeletal 1.03 0.996 – 1.06 0.0865 5045 50451 all phecode
721.2 Spondylosis with myelopathy Musculoskeletal 1.04 0.896 – 1.22 0.584 189 1899 all phecode
721.8 Other allied disorders of spine Musculoskeletal 1.06 0.948 – 1.18 0.317 352 3519 all phecode
722 Intervertebral disc disorders Musculoskeletal 1.03 1.01 – 1.06 0.00329 8978 89848 all phecode
722.1 Displacement of intervertebral disc Musculoskeletal 1.08 0.987 – 1.18 0.0932 512 5116 all phecode
722.6 Degeneration of intervertebral disc Musculoskeletal 1.05 1.01 – 1.09 0.00828 2831 28328 all phecode
722.8 Postlaminectomy syndrome Musculoskeletal 1.12 0.877 – 1.43 0.366 67 669 all phecode
722.9 Other and unspecified disc disorder Musculoskeletal 1.01 0.981 – 1.04 0.475 4407 44127 all phecode
723 Other disorders of cervical region Musculoskeletal 0.997 0.911 – 1.09 0.943 517 5173 all phecode
723.1 Torticollis Musculoskeletal 0.868 0.71 – 1.06 0.167 107 1068 all phecode
724 Other and unspecified disorders of back Musculoskeletal 1.03 0.981 – 1.07 0.257 2052 20514 all phecode
724.1 Disorders of sacrum Musculoskeletal 1.09 0.979 – 1.2 0.118 403 4024 all phecode
724.2 Disorders of coccyx Musculoskeletal 1.08 0.972 – 1.19 0.159 406 4054 all phecode
724.8 Other symptoms referable to back Musculoskeletal 1.31 1.03 – 1.68 0.0306 63 630 all phecode
724.9 Other unspecified back disorders Musculoskeletal 1.01 0.956 – 1.06 0.814 1614 16139 all phecode
726 Peripheral enthesopathies and allied syndromes Musculoskeletal 1.04 1.02 – 1.06 1.6e-06 14663 146691 all phecode
726.1 Enthesopathy Musculoskeletal 1.04 1.02 – 1.06 0.000345 9589 95900 all phecode
726.2 Synoviopathy Musculoskeletal 1.09 0.976 – 1.22 0.125 334 3336 all phecode
726.3 Bursitis Musculoskeletal 1.08 1.01 – 1.16 0.0293 854 8573 all phecode
727 Other disorders of synovium, tendon, and bursa Musculoskeletal 1.04 1.01 – 1.06 0.00223 7331 73332 all phecode
727.1 Synovitis and tenosynovitis Musculoskeletal 1.06 1.02 – 1.1 0.00403 2737 27406 all phecode
727.2 Bursitis disorders Musculoskeletal 0.969 0.795 – 1.18 0.758 103 1029 all phecode
727.4 Ganglion and cyst of synovium, tendon, and bursa Musculoskeletal 1.02 0.984 – 1.06 0.263 3109 31085 all phecode
727.5 Rupture of synovium Musculoskeletal 1.04 0.955 – 1.13 0.375 586 5854 all phecode
727.6 Rupture of tendon, nontraumatic Musculoskeletal 1.05 0.943 – 1.18 0.357 353 3527 all phecode
727.7 Contracture of tendon (sheath) Musculoskeletal 1.07 0.906 – 1.27 0.407 143 1429 all phecode
728 Disorders of muscle, ligament, and fascia Musculoskeletal 1.05 1.02 – 1.09 0.0021 3677 36788 all phecode
728.2 Laxity of ligament or hypermobility syndrome Musculoskeletal 1 0.905 – 1.11 0.971 412 4115 all phecode
728.7 Fasciitis Musculoskeletal 1.05 1.02 – 1.09 0.00244 3803 38045 all phecode
728.71
Contracture of palmar fascia [Dupuytren's
Contracture of palmar fascia [Dupuytren's disease]
 Musculoskeletal 1.06 1.02 – 1.1 0.00118 3477 34788 all phecode
729 Other disorders of soft tissues Musculoskeletal 1.05 1.02 – 1.08 0.000334 6014 60309 all phecode
729.1 Rheumatism, unspecified and fibrositis Musculoskeletal 1 0.939 – 1.07 0.961 1005 10063 all phecode
729.3 Panniculitis Musculoskeletal 0.968 0.79 – 1.19 0.752 101 1009 all phecode
731
Osteitis deformans and osteopathies associated
Osteitis deformans and osteopathies associated with other disorders classified elsewhere
 Musculoskeletal 1.08 0.956 – 1.23 0.212 276 2758 all phecode
731.1 Osteitis deformans [Paget's disease of bone] Musculoskeletal 1.07 0.947 – 1.22 0.267 261 2609 all phecode
732 Osteochondropathies Musculoskeletal 1.09 0.992 – 1.2 0.0721 467 4679 all phecode
732.1 Juvenile osteochondrosis Musculoskeletal 1.05 0.909 – 1.21 0.514 207 2068 all phecode
732.7 Osteochondritis dissecans Musculoskeletal 0.917 0.709 – 1.19 0.512 57 570 all phecode
733 Other disorders of bone and cartilage Musculoskeletal 0.99 0.943 – 1.04 0.698 1777 17814 all phecode
733.2 Cyst of bone Musculoskeletal 0.965 0.857 – 1.09 0.559 311 3115 all phecode
733.4 Aseptic necrosis of bone Musculoskeletal 1.04 0.955 – 1.14 0.349 540 5393 all phecode
733.6 Costochondritis Musculoskeletal 1.1 0.922 – 1.32 0.283 128 1276 all phecode
733.8 Malunion and nonunion of fracture Musculoskeletal 1.01 0.958 – 1.08 0.62 1231 12313 all phecode
733.9 Chondromalacia Musculoskeletal 1.13 0.93 – 1.36 0.223 121 1206 all phecode
735 Acquired foot deformities Musculoskeletal 0.997 0.976 – 1.02 0.783 9603 96090 all phecode
735.1 Flat foot Musculoskeletal 0.946 0.815 – 1.1 0.463 189 1910 all phecode
735.2 Acquired toe deformities Musculoskeletal 1.01 0.984 – 1.04 0.389 5070 50712 all phecode
735.21 Hammer toe (acquired) Musculoskeletal 1.03 0.98 – 1.08 0.264 1929 19324 all phecode
735.23 Hallux rigidus Musculoskeletal 1.01 0.957 – 1.06 0.752 1555 15527 all phecode
735.3 Hallux valgus (Bunion) Musculoskeletal 0.985 0.961 – 1.01 0.256 6643 66463 all phecode
736 Other acquired deformities of limbs Musculoskeletal 1.05 0.998 – 1.11 0.059 1627 16282 all phecode
736.2 Acquired deformities of finger Musculoskeletal 0.967 0.851 – 1.1 0.612 248 2476 all phecode
737 Curvature of spine Musculoskeletal 0.997 0.937 – 1.06 0.917 1128 11300 all phecode
737.3 Kyphoscoliosis and scoliosis Musculoskeletal 0.992 0.931 – 1.06 0.8 1061 10632 all phecode
738 Other acquired musculoskeletal deformity Musculoskeletal 1.02 0.976 – 1.07 0.349 1904 19058 all phecode
738.4 Acquired spondylolisthesis Musculoskeletal 1.03 0.981 – 1.09 0.212 1513 15147 all phecode
739 Contracture of joint Musculoskeletal 0.962 0.877 – 1.05 0.405 488 4884 all phecode
740 Osteoarthrosis Musculoskeletal 1.03 1.02 – 1.05 3.68e-07 27707 231603 all phecode
740.1 Osteoarthritis; localized Musculoskeletal 1.03 1.02 – 1.05 0.000122 17412 169419 all phecode
740.11 Osteoarthrosis, localized, primary Musculoskeletal 1.04 1.02 – 1.06 0.000226 8974 89750 all phecode
740.12 Osteoarthrosis, localized, secondary Musculoskeletal 1.01 0.904 – 1.13 0.868 348 3474 all phecode
740.2 Osteoarthrosis, generalized Musculoskeletal 0.997 0.918 – 1.08 0.951 598 5969 all phecode
740.9 Osteoarthrosis NOS Musculoskeletal 1.04 1.02 – 1.05 0.000279 12270 122792 all phecode
741 Symptoms and disorders of the joints Musculoskeletal 1.04 1.01 – 1.08 0.0195 3563 35648 all phecode
741.1 Ankylosis of joint Musculoskeletal 1.24 1.02 – 1.51 0.0346 102 1019 all phecode
741.2 Stiffness of joint Musculoskeletal 1.03 0.953 – 1.12 0.416 614 6146 all phecode
741.3 Difficulty in walking Musculoskeletal 0.972 0.824 – 1.15 0.732 154 1540 all phecode
741.4 Joint effusions Musculoskeletal 1.07 1.01 – 1.13 0.0165 1418 14197 all phecode
741.5 Hemarthrosis Musculoskeletal 1.1 0.901 – 1.34 0.349 110 1100 all phecode
741.6 Villonodular synovitis Musculoskeletal 1.01 0.767 – 1.34 0.924 54 535 all phecode
742 Derangement of joint, non-traumatic Musculoskeletal 1.03 0.991 – 1.07 0.134 2843 28441 all phecode
742.1 Loose body in joint Musculoskeletal 1.06 0.949 – 1.19 0.292 333 3337 all phecode
742.2
Pathological, developmental or recurrent
Pathological, developmental or recurrent dislocation
 Musculoskeletal 1.09 0.888 – 1.35 0.398 95 960 all phecode
742.8 Articular cartilage disorder Musculoskeletal 1.06 0.963 – 1.16 0.244 500 4996 all phecode
742.9 Other derangement of joint Musculoskeletal 1.02 0.977 – 1.07 0.332 1993 19926 all phecode
743
Osteoporosis, osteopenia and pathological
Osteoporosis, osteopenia and pathological fracture
 Musculoskeletal 0.98 0.957 – 1 0.0926 7563 75729 all phecode
743.1 Osteoporosis Musculoskeletal 0.975 0.95 – 1 0.051 6400 64107 all phecode
743.11 Osteoporosis NOS Musculoskeletal 0.969 0.943 – 0.996 0.027 5549 55604 all phecode
743.13 Other specified osteoporosis Musculoskeletal 0.989 0.904 – 1.08 0.806 529 5283 all phecode
743.2 Pathologic fracture Musculoskeletal 1.03 0.945 – 1.13 0.487 516 5179 all phecode
743.9
Osteopenia or other disorder of bone and
Osteopenia or other disorder of bone and cartilage
 Musculoskeletal 0.985 0.916 – 1.06 0.677 815 8144 all phecode
745 Pain in joint Musculoskeletal 1.04 1.02 – 1.07 0.000577 7975 79789 all phecode
747 Cardiac and circulatory congenital anomalies Congenital Anomalies 0.998 0.96 – 1.04 0.919 2802 28058 all phecode
747.1 Cardiac congenital anomalies Congenital Anomalies 0.999 0.959 – 1.04 0.943 2628 26323 all phecode
747.11 Cardiac shunt/ heart septal defect Congenital Anomalies 0.888 0.815 – 0.968 0.00696 584 5838 all phecode
747.12 Valvular heart disease/ heart chambers Congenital Anomalies 0.946 0.829 – 1.08 0.415 235 2358 all phecode
747.13 Congenital anomalies of great vessels Congenital Anomalies 1.05 1 – 1.11 0.0349 1816 18200 all phecode
747.2
Congenital anomalies of peripheral vascular
Congenital anomalies of peripheral vascular system
 Congenital Anomalies 0.953 0.811 – 1.12 0.56 167 1680 all phecode
748 Anomalies of respiratory system, congenital Congenital Anomalies 1.22 0.921 – 1.61 0.166 51 510 all phecode
749 Congenital anomalies of face and neck Congenital Anomalies 0.845 0.753 – 0.949 0.00436 303 3029 all phecode
750 Digestive congenital anomalies Congenital Anomalies 0.933 0.863 – 1.01 0.0851 686 6870 all phecode
750.1 Upper gastrointestinal congenital anomalies Congenital Anomalies 0.913 0.815 – 1.02 0.114 327 3263 all phecode
750.13 Congenital anomalies of mouth/tongue Congenital Anomalies 0.857 0.739 – 0.994 0.0418 191 1909 all phecode
750.2 Lower gastrointestinal congenital anomalies Congenital Anomalies 0.96 0.86 – 1.07 0.462 356 3574 all phecode
750.21 Congenital anomalies of intestine Congenital Anomalies 0.942 0.82 – 1.08 0.393 225 2256 all phecode
750.22
Congenital anomaly of gallbladder, bile ducts
Congenital anomaly of gallbladder, bile ducts, liver, pancreas
 Congenital Anomalies 1.04 0.861 – 1.25 0.69 117 1179 all phecode
751 Genitourinary congenital anomalies Congenital Anomalies 0.997 0.946 – 1.05 0.904 1527 15286 all phecode
751.1 Congenital anomalies of genital organs Congenital Anomalies 0.997 0.923 – 1.08 0.943 694 6932 all phecode
751.11 Congenital anomalies of female genital organs Congenital Anomalies 1.08 0.978 – 1.19 0.133 455 4546 all phecode
751.12 Congenital anomalies of male genital organs Congenital Anomalies 0.87 0.761 – 0.994 0.0402 222 2217 all phecode
751.2 Congenital anomalies of urinary system Congenital Anomalies 1 0.935 – 1.08 0.93 836 8385 all phecode
751.21 Cystic kidney disease Congenital Anomalies 0.943 0.853 – 1.04 0.254 424 4246 all phecode
751.22 Other specified congenital anomalies of kidney Congenital Anomalies 1.04 0.928 – 1.16 0.518 333 3346 all phecode
752 Nervous system congenital anomalies Congenital Anomalies 1.01 0.897 – 1.13 0.907 328 3307 all phecode
752.1 Neural tube defects Congenital Anomalies 0.937 0.82 – 1.07 0.334 253 2557 all phecode
752.11 Spina bifida Congenital Anomalies 0.954 0.824 – 1.11 0.532 208 2108 all phecode
752.2
Other specified congenital anomalies of nervous
Other specified congenital anomalies of nervous system
 Congenital Anomalies 1.38 1.09 – 1.74 0.00808 78 780 all phecode
753 Congenital anomalies of the eye Congenital Anomalies 1.03 0.855 – 1.24 0.75 127 1270 all phecode
753.1 Congenital cataract and lens anomalies Congenital Anomalies 0.962 0.756 – 1.22 0.752 76 760 all phecode
754 Congenital musculoskeletal deformities of spine Congenital Anomalies 1.07 0.882 – 1.31 0.479 109 1099 all phecode
755 Congenital anomalies of limbs Congenital Anomalies 1.06 0.964 – 1.18 0.215 425 4276 all phecode
755.1 Congenital deformities of feet Congenital Anomalies 1.08 0.936 – 1.25 0.291 208 2086 all phecode
755.6
Other congenital anomalies of lower limb
Other congenital anomalies of lower limb, including pelvic girdle
 Congenital Anomalies 1.02 0.863 – 1.2 0.846 160 1620 all phecode
755.61 Congenital hip dysplasia and deformity Congenital Anomalies 1.01 0.826 – 1.23 0.949 106 1070 all phecode
756 Other congenital musculoskeletal anomalies Congenital Anomalies 0.957 0.879 – 1.04 0.302 587 5872 all phecode
756.3
Congenital anomalies of muscle, tendon, fascia
Congenital anomalies of muscle, tendon, fascia, and connective tissue
 Congenital Anomalies 0.898 0.719 – 1.12 0.347 81 810 all phecode
756.5 Congenital osteodystrophies Congenital Anomalies 1.01 0.911 – 1.11 0.918 435 4356 all phecode
758 Chromosomal anomalies and genetic disorders Congenital Anomalies 0.871 0.738 – 1.03 0.101 148 1708 all phecode
758.1 Chromosomal anomalies Congenital Anomalies 0.814 0.63 – 1.05 0.116 60 830 all phecode
759 Other and unspecified congenital anomalies Congenital Anomalies 1.01 0.882 – 1.16 0.854 216 2159 all phecode
759.1 Anomalies of endocrine glands, congenital Congenital Anomalies 1.01 0.817 – 1.24 0.958 96 959 all phecode
760 Back pain Symptoms 1.03 1.01 – 1.05 0.00064 11126 111353 all phecode
761 Cervicalgia Symptoms 1.06 1.01 – 1.11 0.0177 1791 17901 all phecode
764 Sciatica Symptoms 1.04 1 – 1.09 0.0443 2372 23732 all phecode
766 Neuralgia, neuritis, and radiculitis NOS Symptoms 1.03 0.974 – 1.1 0.276 1172 11738 all phecode
770 Myalgia and myositis unspecified Symptoms 1 0.923 – 1.09 0.954 631 6311 all phecode
771 Musculoskeletal symptoms referable to limbs Symptoms 1.06 0.993 – 1.14 0.0804 870 8687 all phecode
771.1 Swelling of limb Symptoms 1.05 1.02 – 1.08 0.00103 4617 46330 all phecode
772 Symptoms of the muscles Symptoms 1.07 0.99 – 1.17 0.0848 659 6581 all phecode
773 Pain in limb Symptoms 1.05 1.03 – 1.08 7.89e-05 6209 62203 all phecode
780 Hypothermia/Chills Symptoms 1.14 0.974 – 1.34 0.101 171 1719 all phecode
781
Symptoms involving nervous and musculoskeletal
Symptoms involving nervous and musculoskeletal systems
 Symptoms 1.03 0.983 – 1.08 0.211 1870 18715 all phecode
782.3 Edema Symptoms 1.04 0.987 – 1.09 0.148 1642 16450 all phecode
782.6 Pallor and flushing Symptoms 1.11 0.956 – 1.3 0.169 175 1748 all phecode
783 Fever of unknown origin Symptoms 1 0.971 – 1.04 0.859 3911 39105 all phecode
785 Abdominal pain Symptoms 1.02 1.01 – 1.03 0.00192 40080 301686 all phecode
788 Syncope and collapse Symptoms 1.03 1.01 – 1.06 0.00232 9069 90813 all phecode
789 Nausea and vomiting Symptoms 1.03 1.01 – 1.05 0.00483 11577 115807 all phecode
790 Nonspecific findings on examination of blood Symptoms 0.976 0.83 – 1.15 0.772 150 1500 all phecode
790.1 Elevated sedimentation rate Symptoms 1.17 0.939 – 1.46 0.162 84 840 all phecode
790.6 Other abnormal blood chemistry Symptoms 1.02 0.996 – 1.05 0.101 6357 63635 all phecode
791 Gangrene Symptoms 1.23 1.12 – 1.34 4.9e-06 549 5501 all phecode
792
Abnormal Papanicolaou smear of cervix and
Abnormal Papanicolaou smear of cervix and cervical HPV
 Symptoms 0.812 0.658 – 1 0.0539 98 966 all phecode
793
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of musculoskeletal system
 Symptoms 0.83 0.696 – 0.991 0.0394 134 1340 all phecode
793.2
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of other intrathoracic organs (echocardiogram, etc)
 Symptoms 1.05 0.965 – 1.15 0.251 565 5647 all phecode
794
Abnormal results of other function studies
Abnormal results of other function studies (bladder, pancreas, placenta, spleen, etc)
 Symptoms 1.03 0.862 – 1.23 0.759 120 1198 all phecode
797 Shock Symptoms 1.05 0.886 – 1.23 0.598 156 1559 all phecode
797.1 Cardiogenic shock Symptoms 1.12 0.919 – 1.37 0.257 102 1020 all phecode
798 Malaise and fatigue Symptoms 1.03 0.996 – 1.07 0.0822 3408 34103 all phecode
798.1 Chronic fatigue syndrome Symptoms 1.05 0.968 – 1.15 0.228 591 5913 all phecode
800 Fracture of lower limb Injuries & Poisonings 1.03 1 – 1.05 0.0229 7035 70329 all phecode
800.1 Fracture of neck of femur Injuries & Poisonings 0.963 0.918 – 1.01 0.125 1815 18152 all phecode
800.2 Fracture of unspecified part of femur Injuries & Poisonings 1.05 0.894 – 1.22 0.574 170 1693 all phecode
800.3 Fracture of tibia and fibula Injuries & Poisonings 1.05 1.01 – 1.1 0.0195 2158 21577 all phecode
800.4 Fracture of patella Injuries & Poisonings 1.06 0.985 – 1.14 0.12 766 7661 all phecode
801 Fracture of ankle and foot Injuries & Poisonings 1.03 0.984 – 1.07 0.226 2205 22041 all phecode
801.1 Fracture of foot Injuries & Poisonings 1.04 0.991 – 1.09 0.112 1835 18346 all phecode
802 Fracture of pelvis Injuries & Poisonings 0.956 0.885 – 1.03 0.244 718 7185 all phecode
803 Fracture of upper limb Injuries & Poisonings 0.971 0.949 – 0.993 0.00965 8288 82880 all phecode
803.1 Fracture of humerus Injuries & Poisonings 1.03 0.979 – 1.08 0.261 1691 16883 all phecode
803.2 Fracture of radius and ulna Injuries & Poisonings 0.946 0.919 – 0.973 0.000109 5215 52171 all phecode
803.3 Fracture of clavicle or scapula Injuries & Poisonings 0.969 0.919 – 1.02 0.253 1518 15186 all phecode
804 Fracture of hand or wrist Injuries & Poisonings 0.962 0.928 – 0.997 0.0332 3339 33384 all phecode
805
Fracture of vertebral column without mention of
Fracture of vertebral column without mention of spinal cord injury
 Injuries & Poisonings 1.05 0.99 – 1.11 0.107 1358 13565 all phecode
807 Fracture of ribs Injuries & Poisonings 0.949 0.882 – 1.02 0.159 776 7752 all phecode
809 Fracture of unspecified bones Injuries & Poisonings 0.997 0.942 – 1.06 0.919 1300 12998 all phecode
817 Concussion Injuries & Poisonings 1.02 0.891 – 1.16 0.795 243 2428 all phecode
818 Intracranial hemorrhage (injury) Injuries & Poisonings 0.934 0.854 – 1.02 0.132 522 5213 all phecode
819
Skull and face fracture and other intercranial
Skull and face fracture and other intercranial injury
 Injuries & Poisonings 1.01 0.969 – 1.04 0.744 2957 29596 all phecode
823 Torus fracture Injuries & Poisonings 1.05 0.994 – 1.1 0.0835 1673 16710 all phecode
830 Dislocation Injuries & Poisonings 1 0.959 – 1.05 0.882 2088 20872 all phecode
835 Internal derangement of knee Injuries & Poisonings 1.03 1.01 – 1.05 0.000433 15221 152247 all phecode
836 Traumatic arthropathy Injuries & Poisonings 1.16 1.06 – 1.27 0.00102 526 5267 all phecode
840 Sprains and strains Injuries & Poisonings 1.06 0.967 – 1.17 0.209 470 4697 all phecode
850 Hemorrhage or hematoma complicating a procedure Injuries & Poisonings 1.04 1.01 – 1.07 0.00631 5259 52626 all phecode
851
Complications of transplants and reattached
Complications of transplants and reattached limbs
 Injuries & Poisonings 0.939 0.795 – 1.11 0.461 157 1567 all phecode
853 Complication of colostomy or enterostomy Injuries & Poisonings 1.08 0.984 – 1.18 0.106 501 5010 all phecode
854
Complications of cardiac/vascular device
Complications of cardiac/vascular device, implant, and graft
 Injuries & Poisonings 1.09 1.03 – 1.14 0.000814 1826 18238 all phecode
857
Mechanical complication of unspecified
Mechanical complication of unspecified genitourinary device, implant, and graft
 Injuries & Poisonings 1 0.945 – 1.06 0.955 1241 12418 all phecode
858 Complication of internal orthopedic device Injuries & Poisonings 1.04 1 – 1.08 0.0448 3158 31607 all phecode
859
Complication due to other implant and internal
Complication due to other implant and internal device
 Injuries & Poisonings 1.01 0.973 – 1.05 0.619 3259 32599 all phecode
860 Bone marrow or stem cell transplant Neoplasms 0.971 0.753 – 1.25 0.819 68 680 all phecode
870 Open wounds of head; neck; and trunk Injuries & Poisonings 0.995 0.961 – 1.03 0.783 3502 35062 all phecode
870.1 Open wound or laceration of eye or eyelid Injuries & Poisonings 0.928 0.82 – 1.05 0.24 272 2713 all phecode
870.2 Open wound of ear Injuries & Poisonings 1 0.864 – 1.16 0.991 196 1949 all phecode
870.3 Other open wound of head and face Injuries & Poisonings 0.984 0.947 – 1.02 0.394 2904 29085 all phecode
870.4 Open wound of nose and sinus Injuries & Poisonings 0.936 0.816 – 1.07 0.344 220 2199 all phecode
870.6 Open wound of neck Injuries & Poisonings 0.875 0.689 – 1.11 0.274 68 678 all phecode
871 Open wounds of extremities Injuries & Poisonings 0.996 0.964 – 1.03 0.799 4063 40648 all phecode
871.1 Open wound of hand except finger(s) Injuries & Poisonings 1.06 0.809 – 1.4 0.659 53 530 all phecode
871.2 Open wound of finger(s) Injuries & Poisonings 1.22 0.983 – 1.51 0.0718 91 900 all phecode
871.3 Open wound of foot except toe(s) alone Injuries & Poisonings 1.07 0.922 – 1.25 0.357 178 1785 all phecode
872 Traumatic amputation Injuries & Poisonings 0.923 0.84 – 1.01 0.0964 475 4742 all phecode
873 Broken tooth Injuries & Poisonings 1.03 0.903 – 1.18 0.657 229 2289 all phecode
874 Complication of amputation stump Injuries & Poisonings 1.12 0.961 – 1.31 0.143 169 1710 all phecode
905
Late effects of musculoskeletal and connective
Late effects of musculoskeletal and connective tissue injuries
 Injuries & Poisonings 1.07 0.907 – 1.25 0.439 157 1567 all phecode
907 Injuries to the nervous system Injuries & Poisonings 0.99 0.935 – 1.05 0.718 1314 13140 all phecode
915 Superficial injury without mention of infection Injuries & Poisonings 1.01 0.979 – 1.04 0.544 4260 42663 all phecode
916 Contusion Injuries & Poisonings 1.02 0.966 – 1.08 0.48 1450 14506 all phecode
930 Allergic reaction to food Injuries & Poisonings 1.1 0.938 – 1.28 0.25 179 1807 all phecode
938 Dermatitis due to solar radiation Injuries & Poisonings 0.889 0.801 – 0.987 0.0277 389 3899 all phecode
938.2 Chronic dermatitis due to solar radiation Injuries & Poisonings 0.87 0.762 – 0.992 0.0376 252 2530 all phecode
939
Atopic/contact dermatitis due to other or
Atopic/contact dermatitis due to other or unspecified
 Dermatologic 0.997 0.953 – 1.04 0.908 2094 20961 all phecode
941 Adverse reaction to serum or vaccine Injuries & Poisonings 0.994 0.868 – 1.14 0.926 225 2249 all phecode
942 Infusion and transfusion reaction Injuries & Poisonings 1.16 0.951 – 1.42 0.143 104 1038 all phecode
946 Anaphylactic shock NOS Injuries & Poisonings 1.02 0.935 – 1.11 0.661 550 5509 all phecode
947 Urticaria Injuries & Poisonings 1.04 0.934 – 1.16 0.478 371 3707 all phecode
949 Allergies, other Injuries & Poisonings 0.983 0.887 – 1.09 0.745 397 3989 all phecode
952
Spinal cord injury without evidence of spinal
Spinal cord injury without evidence of spinal bone injury
 Injuries & Poisonings 0.994 0.898 – 1.1 0.9 423 4224 all phecode
957 Injury to other and unspecified nerves Injuries & Poisonings 1.12 0.989 – 1.27 0.0739 269 2698 all phecode
958
Certain early complications of trauma or
Certain early complications of trauma or procedure
 Injuries & Poisonings 1.04 0.943 – 1.14 0.458 491 4926 all phecode
958.1 Postoperative shock Injuries & Poisonings 1.23 0.921 – 1.64 0.16 55 555 all phecode
958.2 Traumatic and surgical subcutaneous emphysema Injuries & Poisonings 1.09 0.866 – 1.37 0.467 74 740 all phecode
960 Poisoning by antibiotics Injuries & Poisonings 1.03 1.01 – 1.04 0.000255 18100 181147 all phecode
960.2 Allergy/adverse effect of penicillin Injuries & Poisonings 1.03 1.01 – 1.05 0.000645 15846 158623 all phecode
961 Poisoning by other anti-infectives Injuries & Poisonings 0.987 0.894 – 1.09 0.799 420 4195 all phecode
961.1 Poisoning/allergy of sulfonamides Injuries & Poisonings 0.983 0.917 – 1.05 0.618 869 8703 all phecode
962 Poisoning by hormones and synthetic substitutes Injuries & Poisonings 1.11 0.994 – 1.23 0.0634 371 3707 all phecode
962.3
Hormones and synthetic substitutes causing
Hormones and synthetic substitutes causing adverse effects in therapeutic use
 Injuries & Poisonings 1.11 0.997 – 1.24 0.0566 364 3638 all phecode
963 Poisoning by primarily systemic agents Injuries & Poisonings 1.12 0.972 – 1.28 0.119 223 2228 all phecode
964
Poisoning by agents primarily affecting blood
Poisoning by agents primarily affecting blood constituents
 Injuries & Poisonings 0.978 0.866 – 1.1 0.717 282 2830 all phecode
964.1 Anticoagulants causing adverse effects Injuries & Poisonings 0.965 0.853 – 1.09 0.566 276 2770 all phecode
965
Poisoning by analgesics, antipyretics, and
Poisoning by analgesics, antipyretics, and antirheumatics
 Injuries & Poisonings 1.05 1.02 – 1.08 0.00044 6082 60875 all phecode
965.1
Opiates and related narcotics causing adverse
Opiates and related narcotics causing adverse effects in therapeutic use
 Injuries & Poisonings 1.05 0.99 – 1.12 0.101 1144 11447 all phecode
965.2
Antirheumatics causing adverse effects in
Antirheumatics causing adverse effects in therapeutic use
 Injuries & Poisonings 1 0.911 – 1.1 0.983 476 4767 all phecode
965.3
Salicylates causing adverse effects in
Salicylates causing adverse effects in therapeutic use
 Injuries & Poisonings 1.03 0.929 – 1.14 0.578 403 4045 all phecode
966
Poisoning by anticonvulsants and
Poisoning by anticonvulsants and anti-Parkinsonism drugs
 Injuries & Poisonings 1.02 0.935 – 1.12 0.601 512 5123 all phecode
967
Adverse effects of sedatives or other central
Adverse effects of sedatives or other central nervous system depressants and anesthetics
 Injuries & Poisonings 0.996 0.915 – 1.09 0.934 583 5843 all phecode
969 Poisoning by psychotropic agents Injuries & Poisonings 1.05 1.01 – 1.1 0.0245 1950 19519 all phecode
971
Poisoning by drugs primarily affecting the
Poisoning by drugs primarily affecting the autonomic nervous system
 Injuries & Poisonings 1.06 0.915 – 1.23 0.433 190 1908 all phecode
972
Poisoning by agents primarily affecting the
Poisoning by agents primarily affecting the cardiovascular system
 Injuries & Poisonings 1.05 0.929 – 1.19 0.427 271 2717 all phecode
972.6 Antihypertensive agents causing adverse effects Injuries & Poisonings 1.12 0.894 – 1.41 0.321 84 849 all phecode
973
Poisoning by agents primarily affecting the
Poisoning by agents primarily affecting the gastrointestinal system
 Injuries & Poisonings 1.04 0.85 – 1.27 0.718 108 1080 all phecode
974
Poisoning by water, mineral, and uric acid
Poisoning by water, mineral, and uric acid metabolism drugs
 Injuries & Poisonings 1.14 0.927 – 1.39 0.218 101 1018 all phecode
975
Poisoning by agents primarily acting on the
Poisoning by agents primarily acting on the smooth and skeletal muscles and respiratory system
 Injuries & Poisonings 0.879 0.682 – 1.13 0.318 64 640 all phecode
976
Poisoning by agents primarily affecting skin &
Poisoning by agents primarily affecting skin & mucous membrane, ophthalmological, otorhinolaryngological, & dental drugs
 Injuries & Poisonings 1 0.764 – 1.32 0.981 58 580 all phecode
977 Personal history of allergy to medicinal agents Injuries & Poisonings 1 0.877 – 1.15 0.947 234 2337 all phecode
979 Adverse drug events and drug allergies Injuries & Poisonings 0.994 0.92 – 1.08 0.89 698 6966 all phecode
981
Toxic effect of (non-ethyl) alcohol and
Toxic effect of (non-ethyl) alcohol and petroleum and other solvents
 Injuries & Poisonings 1.02 0.885 – 1.19 0.748 200 1999 all phecode
986 Toxic effect of carbon monoxide Injuries & Poisonings 1.03 0.793 – 1.33 0.842 62 620 all phecode
987 Toxic effect of other gases, fumes, or vapors Injuries & Poisonings 1.1 0.893 – 1.35 0.375 105 1049 all phecode
988 Toxic effect of noxious substances eaten as food Injuries & Poisonings 0.939 0.776 – 1.14 0.523 111 1128 all phecode
989
Toxic effect of other substances, chiefly
Toxic effect of other substances, chiefly nonmedicinal as to source
 Injuries & Poisonings 0.829 0.667 – 1.03 0.0901 89 890 all phecode
990 Effects radiation NOS Injuries & Poisonings 0.985 0.95 – 1.02 0.431 3113 31140 all phecode
994 Sepsis and SIRS Injuries & Poisonings 1.05 1.01 – 1.09 0.0178 3028 30268 all phecode
994.2 Sepsis Injuries & Poisonings 1.05 1.01 – 1.09 0.0178 3028 30268 all phecode
008 Intestinal infection Infectious Diseases 1.02 0.999 – 1.05 0.0563 7801 83500 exclusion phecode
008.5 Bacterial enteritis Infectious Diseases 1.05 1.01 – 1.09 0.0226 2432 25627 exclusion phecode
008.52 Intestinal infection due to C. difficile Infectious Diseases 1.02 0.938 – 1.11 0.613 575 6126 exclusion phecode
008.6 Viral Enteritis Infectious Diseases 1.02 0.942 – 1.1 0.686 743 8128 exclusion phecode
008.7 Intestinal infection due to protozoa Infectious Diseases 1.41 1.07 – 1.87 0.0158 53 526 exclusion phecode
010 Tuberculosis Infectious Diseases 0.995 0.844 – 1.17 0.95 154 1538 exclusion phecode
038 Septicemia Infectious Diseases 1.05 1.01 – 1.08 0.00734 3616 39127 exclusion phecode
038.1 Gram negative septicemia Infectious Diseases 1.1 1.02 – 1.19 0.012 733 7938 exclusion phecode
038.2 Gram positive septicemia Infectious Diseases 1.02 0.918 – 1.12 0.763 413 4672 exclusion phecode
041 Bacterial infection NOS Infectious Diseases 1.01 0.992 – 1.03 0.23 10505 113294 exclusion phecode
041.1 Staphylococcus infections Infectious Diseases 1.01 0.966 – 1.05 0.793 2641 29478 exclusion phecode
041.2 Streptococcus infection Infectious Diseases 1.02 0.968 – 1.08 0.431 1436 15459 exclusion phecode
041.4 E. coli Infectious Diseases 0.986 0.945 – 1.03 0.498 2350 25798 exclusion phecode
053 Herpes zoster Infectious Diseases 1.04 0.939 – 1.16 0.43 370 3849 exclusion phecode
053.1 Herpes zoster with nervous system complications Infectious Diseases 0.938 0.749 – 1.17 0.577 87 886 exclusion phecode
054 Herpes simplex Infectious Diseases 0.983 0.848 – 1.14 0.815 200 1993 exclusion phecode
070 Viral hepatitis Infectious Diseases 1.01 0.927 – 1.11 0.757 527 5587 exclusion phecode
070.1 Viral hepatitis A Infectious Diseases 0.997 0.775 – 1.28 0.983 63 653 exclusion phecode
070.2 Viral hepatitis B Infectious Diseases 0.975 0.81 – 1.17 0.791 118 1254 exclusion phecode
070.3 Viral hepatitis C Infectious Diseases 0.931 0.815 – 1.06 0.293 234 2444 exclusion phecode
070.4 Chronic hepatitis Infectious Diseases 0.944 0.826 – 1.08 0.398 243 2621 exclusion phecode
070.9 Hepatitis NOS Infectious Diseases 1 0.897 – 1.12 0.962 317 4032 exclusion phecode
071 Human immunodeficiency virus [HIV] disease Infectious Diseases 0.998 0.836 – 1.19 0.985 137 1384 exclusion phecode
071.1 HIV infection, symptomatic Infectious Diseases 1.04 0.851 – 1.27 0.704 107 1090 exclusion phecode
078 Viral warts & HPV Infectious Diseases 1.06 0.994 – 1.14 0.0722 927 9515 exclusion phecode
079 Viral infection Infectious Diseases 0.997 0.958 – 1.04 0.901 2526 26371 exclusion phecode
079.1 Varicella infection Infectious Diseases 1.01 0.786 – 1.3 0.932 61 613 exclusion phecode
080 Postoperative infection Infectious Diseases 1.03 0.997 – 1.06 0.0715 3928 42268 exclusion phecode
081
Infection/inflammation of internal prosthetic
Infection/inflammation of internal prosthetic device; implant; and graft
 Infectious Diseases 1.03 0.982 – 1.07 0.252 2215 23313 exclusion phecode
090
Sexually transmitted infections (not HIV or
Sexually transmitted infections (not HIV or hepatitis)
 Infectious Diseases 0.997 0.769 – 1.29 0.984 60 662 exclusion phecode
1000 Burns Injuries & Poisonings 0.964 0.881 – 1.05 0.418 527 5463 exclusion phecode
1001 Foreign body injury Injuries & Poisonings 0.98 0.922 – 1.04 0.515 1110 11318 exclusion phecode
1002
Symptoms concerning nutrition, metabolism, and
Symptoms concerning nutrition, metabolism, and development
 Injuries & Poisonings 0.978 0.95 – 1.01 0.133 4996 51572 exclusion phecode
1004
Other signs and symptoms involving emotional
Other signs and symptoms involving emotional state
 Injuries & Poisonings 0.926 0.819 – 1.05 0.225 265 2835 exclusion phecode
1005 Other symptoms Injuries & Poisonings 0.984 0.929 – 1.04 0.579 1294 13556 exclusion phecode
1006 Crushing injury Injuries & Poisonings 0.871 0.761 – 0.997 0.0458 237 2403 exclusion phecode
1007 Injury to blood vessels Injuries & Poisonings 0.988 0.863 – 1.13 0.855 236 2392 exclusion phecode
1008 Crushing or internal injury to organs Injuries & Poisonings 1 0.936 – 1.07 0.981 944 9490 exclusion phecode
1009 Injury, NOS Injuries & Poisonings 0.996 0.973 – 1.02 0.721 7818 80029 exclusion phecode
1010 Other tests Injuries & Poisonings 1.01 0.985 – 1.04 0.346 5217 55996 exclusion phecode
1011 Complications of surgical and medical procedures Injuries & Poisonings 1.03 1 – 1.05 0.0193 8339 85978 exclusion phecode
1012 Late effect Injuries & Poisonings 1.02 0.827 – 1.26 0.843 95 998 exclusion phecode
1013 Asphyxia and hypoxemia Injuries & Poisonings 1.02 0.901 – 1.15 0.799 283 2995 exclusion phecode
1014 Effects of heat, cold and air pressure Injuries & Poisonings 0.891 0.69 – 1.15 0.379 62 622 exclusion phecode
1015 Effects of other external causes Injuries & Poisonings 1.03 0.994 – 1.06 0.106 3770 40032 exclusion phecode
1019
Other ill-defined and unknown causes of
Other ill-defined and unknown causes of morbidity and mortality
 Injuries & Poisonings 1.02 1 – 1.04 0.0317 14592 150541 exclusion phecode
110 Dermatophytosis / Dermatomycosis Infectious Diseases 1.06 0.929 – 1.2 0.4 252 2617 exclusion phecode
110.1 Dermatophytosis Infectious Diseases 1.07 0.935 – 1.21 0.343 247 2562 exclusion phecode
110.11 Dermatophytosis of nail Infectious Diseases 1.06 0.83 – 1.34 0.662 72 708 exclusion phecode
110.12 Althete's foot Infectious Diseases 1.02 0.855 – 1.22 0.826 126 1320 exclusion phecode
112 Candidiasis Infectious Diseases 1.02 0.97 – 1.07 0.478 1898 19991 exclusion phecode
117 Mycoses Infectious Diseases 0.99 0.869 – 1.13 0.875 248 2530 exclusion phecode
117.4 Aspergillosis Infectious Diseases 0.884 0.746 – 1.05 0.155 151 1525 exclusion phecode
130 Spirochetal infection Infectious Diseases 0.867 0.689 – 1.09 0.223 79 764 exclusion phecode
133 Arthropod-borne diseases Infectious Diseases 0.852 0.659 – 1.1 0.224 64 644 exclusion phecode
134 Helminthiases Infectious Diseases 0.901 0.748 – 1.09 0.275 119 1222 exclusion phecode
134.1 Intestinal helminthiases Infectious Diseases 0.913 0.745 – 1.12 0.382 99 1022 exclusion phecode
136 Other infectious and parasitic diseases Infectious Diseases 1.06 0.908 – 1.23 0.478 189 1924 exclusion phecode
145 Cancer of mouth Neoplasms 1.04 0.959 – 1.14 0.32 608 5992 exclusion phecode
145.2 Cancer of tongue Neoplasms 1.02 0.9 – 1.15 0.792 292 2888 exclusion phecode
145.3 Cancer of major salivary glands Neoplasms 1.08 0.888 – 1.31 0.446 104 996 exclusion phecode
145.5 Cancer of the mouth floor Neoplasms 1.04 0.766 – 1.41 0.8 49 502 exclusion phecode
149 Cancer of larynx, pharynx, nasal cavities Neoplasms 1.05 0.968 – 1.15 0.225 572 5872 exclusion phecode
149.1 Cancer of oropharynx Neoplasms 1.03 0.902 – 1.18 0.636 229 2341 exclusion phecode
149.4 Cancer of larynx Neoplasms 1.12 0.974 – 1.28 0.115 231 2424 exclusion phecode
149.9 Cancer of of nasal cavities Neoplasms 1.01 0.757 – 1.34 0.971 55 543 exclusion phecode
150 Cancer of esophagus Neoplasms 0.997 0.922 – 1.08 0.933 676 7038 exclusion phecode
151 Cancer of stomach Neoplasms 1.01 0.927 – 1.11 0.753 504 5252 exclusion phecode
153 Colorectal cancer Neoplasms 0.992 0.961 – 1.02 0.615 4216 42788 exclusion phecode
153.2 Colon cancer Neoplasms 0.989 0.952 – 1.03 0.585 2858 28989 exclusion phecode
153.3
Malignant neoplasm of rectum, rectosigmoid
Malignant neoplasm of rectum, rectosigmoid junction, and anus
 Neoplasms 0.979 0.935 – 1.03 0.382 1984 20217 exclusion phecode
155 Cancer of liver and intrahepatic bile duct Neoplasms 0.94 0.838 – 1.05 0.294 327 3715 exclusion phecode
155.1 Malignant neoplasm of liver, primary Neoplasms 0.995 0.822 – 1.2 0.955 114 1454 exclusion phecode
157 Pancreatic cancer Neoplasms 1 0.923 – 1.09 0.909 576 6096 exclusion phecode
158
Neoplasm of unspecified nature of digestive
Neoplasm of unspecified nature of digestive system
 Neoplasms 0.978 0.915 – 1.04 0.51 967 9951 exclusion phecode
159
Malignant neoplasm of other and ill-defined
Malignant neoplasm of other and ill-defined sites within the digestive organs and peritoneum
 Neoplasms 0.975 0.947 – 1 0.0826 5079 51987 exclusion phecode
159.2
Malignant neoplasm of small intestine
Malignant neoplasm of small intestine, including duodenum
 Neoplasms 0.939 0.804 – 1.1 0.422 172 1773 exclusion phecode
159.3
Malignant neoplasm of gallbladder and
Malignant neoplasm of gallbladder and extrahepatic bile ducts
 Neoplasms 1.01 0.874 – 1.18 0.849 183 1911 exclusion phecode
159.4
Malignant neoplasm of retroperitoneum and
Malignant neoplasm of retroperitoneum and peritoneum
 Neoplasms 1.07 0.917 – 1.24 0.399 177 1800 exclusion phecode
164 Cancer of intrathoracic organs Neoplasms 1.1 0.846 – 1.44 0.471 56 562 exclusion phecode
165 Cancer within the respiratory system Neoplasms 1.03 0.984 – 1.07 0.23 2559 26211 exclusion phecode
165.1 Cancer of bronchus; lung Neoplasms 1.02 0.971 – 1.06 0.474 2019 20736 exclusion phecode
170 Cancer of bone and connective tissue Neoplasms 0.979 0.883 – 1.09 0.691 407 4098 exclusion phecode
170.1 Bone cancer Neoplasms 1.13 0.937 – 1.36 0.201 123 1237 exclusion phecode
170.2 Cancer of connective tissue Neoplasms 0.933 0.828 – 1.05 0.254 308 3112 exclusion phecode
172 Skin cancer Neoplasms 0.993 0.975 – 1.01 0.448 12674 126217 exclusion phecode
172.1 Melanomas of skin, dx or hx Neoplasms 0.989 0.95 – 1.03 0.605 2538 25249 exclusion phecode
172.11 Melanomas of skin Neoplasms 0.99 0.95 – 1.03 0.614 2568 25565 exclusion phecode
172.2 Other non-epithelial cancer of skin Neoplasms 0.994 0.974 – 1.01 0.564 10324 102723 exclusion phecode
172.3 Carcinoma in situ of skin Neoplasms 0.988 0.91 – 1.07 0.785 617 6227 exclusion phecode
173 Neoplasm of uncertain behavior of skin Neoplasms 1.05 0.896 – 1.22 0.566 169 1726 exclusion phecode
174 Breast cancer Neoplasms 0.993 0.974 – 1.01 0.435 12089 121554 exclusion phecode
174.1 Breast cancer [female] Neoplasms 0.995 0.976 – 1.01 0.582 11895 119587 exclusion phecode
174.11 Malignant neoplasm of female breast Neoplasms 0.997 0.978 – 1.02 0.74 11201 112851 exclusion phecode
174.3 Neoplasm of uncertain behavior of breast Neoplasms 1.14 0.932 – 1.4 0.2 109 1103 exclusion phecode
175 Acquired absence of breast Neoplasms 0.964 0.923 – 1.01 0.0997 2267 23059 exclusion phecode
180 Cervical cancer and dysplasia Neoplasms 1 0.959 – 1.05 0.903 2101 21052 exclusion phecode
180.1 Cervical cancer Neoplasms 1.01 0.891 – 1.15 0.846 263 2628 exclusion phecode
180.3
Cervical intraepithelial neoplasia [CIN]
Cervical intraepithelial neoplasia [CIN] [Cervical dysplasia]
 Neoplasms 1.01 0.968 – 1.06 0.573 2006 20110 exclusion phecode
182 Malignant neoplasm of uterus Neoplasms 1.01 0.951 – 1.07 0.754 1172 12252 exclusion phecode
184 Cancer of other female genital organs Neoplasms 1.03 0.969 – 1.09 0.377 1317 13206 exclusion phecode
184.1
Malignant neoplasm of ovary and other uterine
Malignant neoplasm of ovary and other uterine adnexa
 Neoplasms 1.03 0.965 – 1.1 0.36 926 9253 exclusion phecode
184.11 Malignant neoplasm of ovary Neoplasms 1.05 0.976 – 1.12 0.204 899 8989 exclusion phecode
184.2
Cancer of other female genital organs
Cancer of other female genital organs (excluding uterus and ovary)
 Neoplasms 0.991 0.878 – 1.12 0.881 292 2931 exclusion phecode
185 Cancer of prostate Neoplasms 0.987 0.96 – 1.02 0.373 5561 53416 exclusion phecode
187 Cancer of other male genital organs Neoplasms 1.05 0.952 – 1.17 0.311 409 4176 exclusion phecode
187.1
Malignant neoplasm of unspecified male genital
Malignant neoplasm of unspecified male genital organ
 Neoplasms 1.15 0.886 – 1.5 0.29 61 652 exclusion phecode
187.2 Malignant neoplasm of testis Neoplasms 0.946 0.834 – 1.07 0.389 262 2693 exclusion phecode
187.8
Neoplasm of uncertain behavior of male genital
Neoplasm of uncertain behavior of male genital organs
 Neoplasms 1.34 1.08 – 1.66 0.00726 101 1018 exclusion phecode
189
Cancer of urinary organs (incl. kidney and
Cancer of urinary organs (incl. kidney and bladder)
 Neoplasms 1.02 0.985 – 1.05 0.284 3716 38439 exclusion phecode
189.1 Cancer of kidney and renal pelvis Neoplasms 1.06 0.995 – 1.14 0.0679 964 10024 exclusion phecode
189.11 Malignant neoplasm of kidney, except pelvis Neoplasms 1.08 1.01 – 1.15 0.0289 924 9659 exclusion phecode
189.12 Malignant neoplasm of renal pelvis Neoplasms 0.814 0.629 – 1.05 0.119 62 608 exclusion phecode
189.2 Cancer of bladder Neoplasms 1 0.958 – 1.05 0.926 2133 22199 exclusion phecode
189.21 Malignant neoplasm of bladder Neoplasms 1.01 0.962 – 1.06 0.729 1895 19748 exclusion phecode
189.4 Malignant neoplasm of other urinary organs Neoplasms 0.96 0.798 – 1.16 0.669 134 1315 exclusion phecode
190 Cancer of eye Neoplasms 0.964 0.818 – 1.14 0.665 161 1637 exclusion phecode
191
Manlignant and unknown neoplasms of brain and
Manlignant and unknown neoplasms of brain and nervous system
 Neoplasms 0.972 0.897 – 1.05 0.49 649 6455 exclusion phecode
191.1 Cancer of brain and nervous system Neoplasms 0.984 0.9 – 1.08 0.73 536 5303 exclusion phecode
191.11 Cancer of brain Neoplasms 1 0.915 – 1.1 0.926 498 4914 exclusion phecode
193 Thyroid cancer Neoplasms 1.04 0.926 – 1.16 0.528 320 3328 exclusion phecode
194 Cancer of other endocrine glands Neoplasms 0.857 0.683 – 1.08 0.184 81 896 exclusion phecode
195 Cancer, suspected or other Neoplasms 1 0.986 – 1.02 0.792 15717 155208 exclusion phecode
195.1 Malignant neoplasm, other Neoplasms 0.999 0.982 – 1.02 0.898 15068 149539 exclusion phecode
197 Chemotherapy Neoplasms 1.01 0.998 – 1.03 0.0944 19777 201681 exclusion phecode
198 Secondary malignant neoplasm Neoplasms 1 0.979 – 1.02 0.973 8818 89754 exclusion phecode
198.1 Secondary malignancy of lymph nodes Neoplasms 0.976 0.948 – 1 0.1 4996 50682 exclusion phecode
198.2 Secondary malignancy of respiratory organs Neoplasms 0.996 0.952 – 1.04 0.865 2085 21259 exclusion phecode
198.3
Secondary malignant neoplasm of digestive
Secondary malignant neoplasm of digestive systems
 Neoplasms 0.991 0.939 – 1.05 0.753 1433 14603 exclusion phecode
198.4 Secondary malignant neoplasm of liver Neoplasms 0.991 0.95 – 1.03 0.657 2439 24960 exclusion phecode
198.5 Secondary malignancy of brain/spine Neoplasms 0.995 0.924 – 1.07 0.89 798 7968 exclusion phecode
198.6 Secondary malignancy of bone Neoplasms 1.01 0.962 – 1.06 0.734 1979 20192 exclusion phecode
198.7 Secondary malignant neoplasm of skin Neoplasms 1.07 0.914 – 1.25 0.399 174 1775 exclusion phecode
199 Neoplasm of uncertain behavior Neoplasms 1.04 0.979 – 1.1 0.215 1319 13484 exclusion phecode
199.4 Neurofibromatosis Neoplasms 1.09 0.892 – 1.34 0.393 91 905 exclusion phecode
200 Myeloproliferative disease Neoplasms 1.03 0.961 – 1.1 0.398 889 9257 exclusion phecode
200.1 Polycythemia vera Neoplasms 0.986 0.881 – 1.1 0.802 331 3575 exclusion phecode
201 Hodgkin's disease Neoplasms 0.895 0.781 – 1.02 0.108 240 2447 exclusion phecode
202 Cancer of other lymphoid, histiocytic tissue Neoplasms 0.996 0.952 – 1.04 0.855 2095 21255 exclusion phecode
202.2 Non-Hodgkins lymphoma Neoplasms 0.985 0.936 – 1.04 0.543 1669 16881 exclusion phecode
202.21 Nodular lymphoma Neoplasms 0.882 0.788 – 0.986 0.0276 340 3414 exclusion phecode
202.24 Large cell lymphoma Neoplasms 1.04 0.948 – 1.13 0.435 538 5448 exclusion phecode
204 Leukemia Neoplasms 1.06 1.01 – 1.12 0.0254 1528 15471 exclusion phecode
204.1 Lymphoid leukemia Neoplasms 1.05 0.963 – 1.15 0.255 521 5374 exclusion phecode
204.11 Lymphoid leukemia, acute Neoplasms 1.09 0.827 – 1.44 0.54 52 529 exclusion phecode
204.12 Lymphoid leukemia, chronic Neoplasms 1.06 0.963 – 1.17 0.233 453 4700 exclusion phecode
204.2 Myeloid leukemia Neoplasms 1.02 0.927 – 1.12 0.685 436 4302 exclusion phecode
204.21 Myeloid leukemia, acute Neoplasms 1.06 0.951 – 1.19 0.276 311 3041 exclusion phecode
204.22 Myeloid leukemia, chronic Neoplasms 1.05 0.881 – 1.25 0.578 137 1359 exclusion phecode
204.4 Multiple myeloma Neoplasms 1.07 0.981 – 1.17 0.124 517 5179 exclusion phecode
208 Benign neoplasm of colon Neoplasms 1.01 0.998 – 1.03 0.0896 18008 180018 exclusion phecode
210 Benign neoplasm of lip, oral cavity, and pharynx Neoplasms 1.05 0.983 – 1.13 0.146 901 9212 exclusion phecode
211
Benign neoplasm of other parts of digestive
Benign neoplasm of other parts of digestive system
 Neoplasms 1.01 0.976 – 1.04 0.712 4765 49410 exclusion phecode
212
Benign neoplasm of respiratory and
Benign neoplasm of respiratory and intrathoracic organs
 Neoplasms 1.01 0.898 – 1.13 0.924 319 3256 exclusion phecode
213 Benign neoplasm of bone and articular cartilage Neoplasms 0.987 0.877 – 1.11 0.829 304 3023 exclusion phecode
214 Lipoma Neoplasms 1.04 1.01 – 1.07 0.00256 5824 58607 exclusion phecode
214.1 Lipoma of skin and subcutaneous tissue Neoplasms 1.05 1.02 – 1.08 0.00368 4307 43303 exclusion phecode
215
Other benign neoplasm of connective and other
Other benign neoplasm of connective and other soft tissue
 Neoplasms 1.05 0.983 – 1.11 0.156 1055 10460 exclusion phecode
216 Benign neoplasm of skin Neoplasms 1.01 0.985 – 1.03 0.453 7257 72741 exclusion phecode
217 Vascular hamartomas and non-neoplastic nevi Neoplasms 0.979 0.9 – 1.07 0.628 587 5954 exclusion phecode
217.1 Nevus, non-neoplastic Neoplasms 0.985 0.902 – 1.07 0.729 551 5598 exclusion phecode
218 Benign neoplasm of uterus Neoplasms 1.05 1.03 – 1.07 8.7e-06 9606 96769 exclusion phecode
218.1 Uterine leiomyoma Neoplasms 1.05 1.03 – 1.07 1.52e-06 9813 98814 exclusion phecode
218.2 Other benign neoplasm of uterus Neoplasms 1.04 0.928 – 1.16 0.53 336 3427 exclusion phecode
220 Benign neoplasm of ovary Neoplasms 0.985 0.932 – 1.04 0.595 1358 13942 exclusion phecode
221 Benign neoplasm of other female genital organs Neoplasms 1.01 0.875 – 1.17 0.877 200 2113 exclusion phecode
222 Benign neoplasm of male genital organs Neoplasms 0.937 0.788 – 1.11 0.46 148 1462 exclusion phecode
223
Benign neoplasm of kidney and other urinary
Benign neoplasm of kidney and other urinary organs
 Neoplasms 1.15 0.972 – 1.35 0.105 156 1600 exclusion phecode
224 Benign neoplasm of eye Neoplasms 1 0.829 – 1.21 0.969 114 1213 exclusion phecode
224.1 Benign neoplasm of eye, uveal Neoplasms 0.976 0.747 – 1.28 0.861 56 632 exclusion phecode
225
Benign neoplasm of brain and other parts of
Benign neoplasm of brain and other parts of nervous system
 Neoplasms 0.945 0.877 – 1.02 0.134 765 7697 exclusion phecode
225.1
Benign neoplasm of brain, cranial nerves
Benign neoplasm of brain, cranial nerves, meninges
 Neoplasms 0.93 0.862 – 1 0.0665 726 7322 exclusion phecode
225.2 Benign neoplasm of spinal cord, meninges Neoplasms 1.16 0.884 – 1.52 0.288 55 565 exclusion phecode
226 Benign neoplasm of thyroid glands Neoplasms 0.954 0.839 – 1.08 0.471 251 2537 exclusion phecode
227
Benign neoplasm of other endocrine glands and
Benign neoplasm of other endocrine glands and related structures
 Neoplasms 1.02 0.951 – 1.1 0.526 757 8145 exclusion phecode
227.1 Benign neoplasm of adrenal gland Neoplasms 1.04 0.886 – 1.22 0.624 153 1741 exclusion phecode
227.2 Benign neoplasm of parathyroid gland Neoplasms 1.03 0.921 – 1.15 0.61 338 3497 exclusion phecode
227.3
Benign neoplasm of pituitary gland and
Benign neoplasm of pituitary gland and craniopharyngeal duct (pouch)
 Neoplasms 1.01 0.887 – 1.14 0.924 272 2944 exclusion phecode
228 Hemangioma and lymphangioma, any site Neoplasms 0.992 0.94 – 1.05 0.761 1494 15077 exclusion phecode
229 Benign neoplasm of unspecified sites Neoplasms 1.01 0.963 – 1.05 0.812 2281 22844 exclusion phecode
240 Simple and unspecified goiter Endocrine/metabolic 1.04 0.957 – 1.14 0.34 554 5744 exclusion phecode
241 Nontoxic nodular goiter Endocrine/metabolic 1.01 0.944 – 1.07 0.861 1055 10605 exclusion phecode
241.1 Nontoxic uninodular goiter Endocrine/metabolic 1.03 0.931 – 1.13 0.596 453 4518 exclusion phecode
241.2 Nontoxic multinodular goiter Endocrine/metabolic 0.963 0.888 – 1.04 0.362 641 6466 exclusion phecode
242 Thyrotoxicosis with or without goiter Endocrine/metabolic 1.04 0.985 – 1.09 0.17 1673 17648 exclusion phecode
242.1 Graves' disease Endocrine/metabolic 1.03 0.933 – 1.14 0.541 418 4347 exclusion phecode
242.2 Toxic multinodular goiter Endocrine/metabolic 1.04 0.831 – 1.3 0.725 86 869 exclusion phecode
242.3 Exophthalmos Endocrine/metabolic 0.872 0.724 – 1.05 0.148 126 1301 exclusion phecode
244 Hypothyroidism Endocrine/metabolic 1.01 0.994 – 1.03 0.185 13227 138345 exclusion phecode
244.1 Secondary hypothyroidism Endocrine/metabolic 1.02 0.956 – 1.09 0.547 1001 10545 exclusion phecode
244.2 Acquired hypothyroidism Endocrine/metabolic 0.912 0.736 – 1.13 0.403 87 957 exclusion phecode
244.4 Hypothyroidism NOS Endocrine/metabolic 1.01 0.992 – 1.03 0.261 12609 132481 exclusion phecode
245 Thyroiditis Endocrine/metabolic 0.996 0.881 – 1.13 0.955 272 2761 exclusion phecode
245.2 Chronic thyroiditis Endocrine/metabolic 1.08 0.939 – 1.24 0.283 206 2085 exclusion phecode
245.21 Chronic lymphocytic thyroiditis Endocrine/metabolic 1.09 0.946 – 1.25 0.234 201 2015 exclusion phecode
246 Other disorders of thyroid Endocrine/metabolic 0.996 0.896 – 1.11 0.94 371 3790 exclusion phecode
250 Diabetes mellitus Endocrine/metabolic 1.39 1.35 – 1.42 1.06e-130 5756 181935 exclusion phecode
250.1 Type 1 diabetes Endocrine/metabolic 1.19 1.02 – 1.38 0.0248 172 27032 exclusion phecode
250.11 Type 1 diabetes with ketoacidosis Endocrine/metabolic 1.62 0.976 – 2.69 0.0623 12 2342 exclusion phecode
250.12 Type 1 diabetes with renal manifestations Endocrine/metabolic 2.33 0.831 – 6.51 0.108 1 750 exclusion phecode
250.13 Type 1 diabetes with ophthalmic manifestations Endocrine/metabolic 1.93 1.02 – 3.67 0.0436 6 4637 exclusion phecode
250.14 Type 1 diabetes with neurological manifestations Endocrine/metabolic 0.391 0.173 – 0.886 0.0244 3 1587 exclusion phecode
250.2 Type 2 diabetes Endocrine/metabolic 1.44 1.39 – 1.48 7.91e-135 4878 166402 exclusion phecode
250.21 Type 2 diabetes with ketoacidosis Endocrine/metabolic 1.09 0.671 – 1.77 0.726 12 1018 exclusion phecode
250.22 Type 2 diabetes with renal manifestations Endocrine/metabolic 0.926 0.554 – 1.55 0.771 10 1969 exclusion phecode
250.23 Type 2 diabetes with ophthalmic manifestations Endocrine/metabolic 1.63 1.23 – 2.16 0.000629 46 9635 exclusion phecode
250.24 Type 2 diabetes with neurological manifestations Endocrine/metabolic 1.7 1.14 – 2.52 0.00893 21 4949 exclusion phecode
250.4 Abnormal glucose Endocrine/metabolic 1.23 1.12 – 1.36 3.51e-05 423 6683 exclusion phecode
250.41 Impaired fasting glucose Endocrine/metabolic 1.33 1.15 – 1.55 0.000125 186 2598 exclusion phecode
250.42 Other abnormal glucose Endocrine/metabolic 1.17 1.03 – 1.33 0.0171 240 4099 exclusion phecode
250.5 Glycosuria or Acetonuria Endocrine/metabolic 1.17 0.944 – 1.45 0.153 93 1287 exclusion phecode
250.6 Polyneuropathy in diabetes Endocrine/metabolic 1.17 0.737 – 1.85 0.506 14 3419 exclusion phecode
250.7 Diabetic retinopathy Endocrine/metabolic 1.17 0.935 – 1.45 0.173 76 12416 exclusion phecode
251.1 Hypoglycemia Endocrine/metabolic 1.03 0.909 – 1.16 0.67 272 9153 exclusion phecode
252 Disorders of parathyroid gland Endocrine/metabolic 1 0.933 – 1.08 0.92 768 8265 exclusion phecode
252.1 Hyperparathyroidism Endocrine/metabolic 0.999 0.923 – 1.08 0.97 685 7393 exclusion phecode
252.2 Hypoparathyroidism Endocrine/metabolic 1.11 0.924 – 1.33 0.265 124 1345 exclusion phecode
253
Disorders of the pituitary gland and its
Disorders of the pituitary gland and its hypothalamic control
 Endocrine/metabolic 1.01 0.929 – 1.1 0.798 585 6425 exclusion phecode
253.1 Pituitary hyperfunction Endocrine/metabolic 1.05 0.897 – 1.24 0.52 162 1772 exclusion phecode
253.11 Acromegaly and gigantism Endocrine/metabolic 1.1 0.885 – 1.38 0.379 82 901 exclusion phecode
253.2 Pituitary hypofunction Endocrine/metabolic 0.938 0.816 – 1.08 0.364 216 2443 exclusion phecode
253.3 Diabetes insipidus Endocrine/metabolic 1.05 0.819 – 1.34 0.709 70 868 exclusion phecode
253.7 Other disorders of neurohypophysis Endocrine/metabolic 0.968 0.812 – 1.16 0.722 137 1477 exclusion phecode
255 Disorders of adrenal glands Endocrine/metabolic 1.06 0.974 – 1.16 0.17 539 6034 exclusion phecode
255.1 Adrenal hyperfunction Endocrine/metabolic 1.04 0.876 – 1.23 0.661 142 1704 exclusion phecode
255.11 Cushing's syndrome Endocrine/metabolic 1.06 0.847 – 1.34 0.592 79 984 exclusion phecode
255.12 Hyperaldosteronism Endocrine/metabolic 1.1 0.852 – 1.41 0.477 62 724 exclusion phecode
255.2 Adrenal hypofunction Endocrine/metabolic 1.03 0.912 – 1.15 0.676 310 3436 exclusion phecode
255.21 Glucocorticoid deficiency Endocrine/metabolic 1.03 0.916 – 1.16 0.621 309 3426 exclusion phecode
256 Ovarian dysfunction Endocrine/metabolic 1.1 0.963 – 1.26 0.155 223 2355 exclusion phecode
256.4 Polycystic ovaries Endocrine/metabolic 1.11 0.959 – 1.29 0.162 192 2054 exclusion phecode
257 Testicular dysfunction Endocrine/metabolic 0.932 0.779 – 1.11 0.439 134 1510 exclusion phecode
257.1 Testicular hypofunction Endocrine/metabolic 0.986 0.819 – 1.19 0.882 125 1437 exclusion phecode
258 Iatrogenic endocrine disorders Endocrine/metabolic 1.05 0.837 – 1.32 0.661 80 958 exclusion phecode
259 Other endocrine disorders Endocrine/metabolic 0.955 0.798 – 1.14 0.615 133 1439 exclusion phecode
260 Protein-calorie malnutrition Endocrine/metabolic 1.01 0.871 – 1.17 0.893 185 1908 exclusion phecode
260.1 Cachexia Endocrine/metabolic 1.01 0.752 – 1.36 0.933 46 478 exclusion phecode
260.6 Anorexia Endocrine/metabolic 0.952 0.884 – 1.03 0.196 754 7811 exclusion phecode
261 Vitamin deficiency Endocrine/metabolic 0.986 0.925 – 1.05 0.675 1030 11349 exclusion phecode
261.2 Vitamin B-complex deficiencies Endocrine/metabolic 0.955 0.881 – 1.03 0.262 646 7125 exclusion phecode
261.4 Vitamin D deficiency Endocrine/metabolic 1.03 0.929 – 1.14 0.57 387 4256 exclusion phecode
261.41 Rickets or osteomalacia Endocrine/metabolic 1.04 0.826 – 1.32 0.72 71 738 exclusion phecode
262 Mineral deficiency NEC Endocrine/metabolic 0.966 0.839 – 1.11 0.629 216 2262 exclusion phecode
269 Proteinuria Endocrine/metabolic 1.09 0.961 – 1.23 0.186 278 3150 exclusion phecode
270
Disorders of protein plasma/amino-acid
Disorders of protein plasma/amino-acid transport and metabolism
 Endocrine/metabolic 1.07 0.941 – 1.21 0.31 265 2832 exclusion phecode
270.3 Disorders of plasma protein metabolism Endocrine/metabolic 1.04 0.911 – 1.19 0.558 232 2426 exclusion phecode
270.32 Paraproteinemia Endocrine/metabolic 1.07 0.915 – 1.26 0.391 164 1769 exclusion phecode
270.33 Amyloidosis Endocrine/metabolic 1.12 0.922 – 1.36 0.255 104 1061 exclusion phecode
270.35 Macroglobulinemia Endocrine/metabolic 0.936 0.731 – 1.2 0.6 67 646 exclusion phecode
271
Disorders of carbohydrate transport and
Disorders of carbohydrate transport and metabolism
 Endocrine/metabolic 1.26 1.06 – 1.5 0.0105 130 1523 exclusion phecode
271.3
Intestinal disaccharidase deficiencies and
Intestinal disaccharidase deficiencies and disaccharide malabsorption
 Endocrine/metabolic 1.21 1 – 1.45 0.0465 116 1326 exclusion phecode
272 Disorders of lipoid metabolism Endocrine/metabolic 1.05 1.04 – 1.06 1.42e-14 28950 224168 exclusion phecode
272.1 Hyperlipidemia Endocrine/metabolic 1.05 1.04 – 1.06 7.92e-15 28885 223940 exclusion phecode
272.11 Hypercholesterolemia Endocrine/metabolic 1.05 1.04 – 1.06 4.88e-14 26890 217030 exclusion phecode
272.12 Hyperglyceridemia Endocrine/metabolic 1.03 0.776 – 1.37 0.826 47 554 exclusion phecode
272.13 Mixed hyperlipidemia Endocrine/metabolic 1.04 0.871 – 1.25 0.643 120 1555 exclusion phecode
272.9 Unspecified disorder of lipoid metabolism Endocrine/metabolic 1.09 0.926 – 1.28 0.302 161 1985 exclusion phecode
274 Gout and other crystal arthropathies Endocrine/metabolic 1.08 1.04 – 1.12 0.000102 3155 34506 exclusion phecode
274.1 Gout Endocrine/metabolic 1.06 1.02 – 1.11 0.00222 2649 29328 exclusion phecode
274.11 Gouty arthropathy Endocrine/metabolic 1.05 0.851 – 1.29 0.666 94 1039 exclusion phecode
274.2 Crystal arthropathies Endocrine/metabolic 1.15 1.05 – 1.26 0.00185 556 5758 exclusion phecode
274.21 Chondrocalcinosis Endocrine/metabolic 1.16 1.06 – 1.28 0.00123 513 5241 exclusion phecode
275 Disorders of mineral metabolism Endocrine/metabolic 0.998 0.951 – 1.05 0.93 1840 19677 exclusion phecode
275.1 Disorders of iron metabolism Hematopoietic 0.91 0.836 – 0.99 0.0286 577 6082 exclusion phecode
275.3 Disorders of magnesium metabolism Endocrine/metabolic 1.04 0.924 – 1.17 0.507 308 3509 exclusion phecode
275.5 Disorders of calcium/phosphorus metabolism Endocrine/metabolic 1.04 0.973 – 1.1 0.267 1055 11243 exclusion phecode
275.53 Disorders of phosphorus metabolism Endocrine/metabolic 1.05 0.884 – 1.24 0.596 151 1592 exclusion phecode
276
Disorders of fluid, electrolyte, and acid-base
Disorders of fluid, electrolyte, and acid-base balance
 Endocrine/metabolic 1.02 0.99 – 1.04 0.234 6025 68192 exclusion phecode
276.1 Electrolyte imbalance Endocrine/metabolic 1.02 0.984 – 1.06 0.285 3363 38240 exclusion phecode
276.11 Hyperosmolality and/or hypernatremia Endocrine/metabolic 1.04 0.896 – 1.2 0.61 186 2236 exclusion phecode
276.12 Hyposmolality and/or hyponatremia Endocrine/metabolic 0.986 0.936 – 1.04 0.596 1580 17053 exclusion phecode
276.13 Hyperpotassemia Endocrine/metabolic 1.02 0.939 – 1.1 0.681 644 9010 exclusion phecode
276.14 Hypopotassemia Endocrine/metabolic 1.1 1.04 – 1.17 0.00138 1250 13379 exclusion phecode
276.4 Acid-base balance disorder Endocrine/metabolic 1.06 0.994 – 1.14 0.0748 906 10866 exclusion phecode
276.41 Acidosis Endocrine/metabolic 1.05 0.981 – 1.13 0.152 813 9862 exclusion phecode
276.42 Alkalosis Endocrine/metabolic 1.08 0.884 – 1.33 0.438 101 1053 exclusion phecode
276.5 Hypovolemia Endocrine/metabolic 1 0.963 – 1.05 0.835 2355 26504 exclusion phecode
276.6 Fluid overload Endocrine/metabolic 0.977 0.874 – 1.09 0.684 338 4228 exclusion phecode
276.8 Polydipsia Endocrine/metabolic 1.04 0.85 – 1.26 0.726 100 1224 exclusion phecode
277 Other disorders of metabolism Endocrine/metabolic 0.973 0.904 – 1.05 0.472 800 8467 exclusion phecode
277.4 Disorders of bilirubin excretion Endocrine/metabolic 1.01 0.898 – 1.13 0.925 331 3378 exclusion phecode
277.5 Other disorders of lipoid metabolism Endocrine/metabolic 1.06 0.904 – 1.23 0.489 176 2132 exclusion phecode
277.51 Lipoprotein disorders Endocrine/metabolic 0.935 0.677 – 1.29 0.681 38 483 exclusion phecode
278 Overweight, obesity and other hyperalimentation Endocrine/metabolic 1.07 1.05 – 1.09 3.87e-09 8569 102682 exclusion phecode
278.1 Obesity Endocrine/metabolic 1.07 1.04 – 1.09 1.22e-08 8433 101134 exclusion phecode
278.3 Localized adiposity Endocrine/metabolic 1.2 0.946 – 1.51 0.135 75 802 exclusion phecode
278.4 Abnormal weight gain Endocrine/metabolic 1.15 0.863 – 1.53 0.34 52 627 exclusion phecode
279 Disorders involving the immune mechanism Endocrine/metabolic 0.978 0.856 – 1.12 0.749 233 2364 exclusion phecode
279.1 Immunity deficiency Endocrine/metabolic 0.989 0.854 – 1.15 0.887 194 1984 exclusion phecode
279.11 Deficiency of humoral immunity Endocrine/metabolic 0.943 0.785 – 1.13 0.525 131 1313 exclusion phecode
279.7 Other immunological findings Endocrine/metabolic 0.99 0.866 – 1.13 0.883 227 2290 exclusion phecode
280 Iron deficiency anemias Hematopoietic 1.01 0.983 – 1.03 0.509 6465 72172 exclusion phecode
280.1
Iron deficiency anemias, unspecified or not due
Iron deficiency anemias, unspecified or not due to blood loss
 Hematopoietic 1.01 0.985 – 1.04 0.402 6180 69311 exclusion phecode
280.2
Iron deficiency anemia secondary to blood loss
Iron deficiency anemia secondary to blood loss (chronic)
 Hematopoietic 1.01 0.914 – 1.11 0.87 422 4338 exclusion phecode
281 Other deficiency anemia Hematopoietic 1.02 0.954 – 1.09 0.568 932 10541 exclusion phecode
281.1 Megaloblastic anemia Hematopoietic 1.03 0.96 – 1.1 0.436 893 10104 exclusion phecode
281.11 Pernicious anemia Hematopoietic 1.05 0.968 – 1.14 0.235 618 7120 exclusion phecode
281.12 Other vitamin B12 deficiency anemia Hematopoietic 1.05 0.89 – 1.24 0.564 149 1678 exclusion phecode
281.13 Folate-deficiency anemia Hematopoietic 0.922 0.784 – 1.08 0.327 161 1725 exclusion phecode
281.9 Deficiency anemias Hematopoietic 0.923 0.678 – 1.26 0.611 46 514 exclusion phecode
282 Hereditary hemolytic anemias Hematopoietic 1.16 0.975 – 1.37 0.0944 133 1422 exclusion phecode
282.8 Other hemoglobinopathies Hematopoietic 1.23 0.926 – 1.62 0.155 51 531 exclusion phecode
282.9 Other hereditary hemolytic anemias Hematopoietic 1.11 0.875 – 1.41 0.388 72 809 exclusion phecode
283 Acquired hemolytic anemias Hematopoietic 0.987 0.821 – 1.19 0.892 117 1290 exclusion phecode
283.1 Autoimmune hemolytic anemias Hematopoietic 1.04 0.838 – 1.29 0.729 89 996 exclusion phecode
284 Aplastic anemia Hematopoietic 0.999 0.899 – 1.11 0.98 379 4117 exclusion phecode
285 Other anemias Hematopoietic 0.998 0.978 – 1.02 0.862 10456 114585 exclusion phecode
285.1 Acute posthemorrhagic anemia Hematopoietic 1.04 0.914 – 1.18 0.559 253 2590 exclusion phecode
285.2 Anemia of chronic disease Hematopoietic 0.935 0.858 – 1.02 0.128 573 6568 exclusion phecode
285.22 Anemia in neoplastic disease Hematopoietic 0.912 0.82 – 1.01 0.091 381 3904 exclusion phecode
286 Coagulation defects Hematopoietic 0.985 0.917 – 1.06 0.684 825 8736 exclusion phecode
286.1 Congenital coagulation defects Hematopoietic 0.933 0.844 – 1.03 0.176 416 4369 exclusion phecode
286.11 Von willebrand's disease Hematopoietic 0.946 0.762 – 1.17 0.612 91 918 exclusion phecode
286.12
Congenital deficiency of other clotting factors
Congenital deficiency of other clotting factors (including factor VII)
 Hematopoietic 0.955 0.841 – 1.08 0.478 261 2795 exclusion phecode
286.13 Congenital factor VIII disorder Hematopoietic 0.925 0.701 – 1.22 0.585 55 597 exclusion phecode
286.5
Hemorrhagic disorder due to intrinsic
Hemorrhagic disorder due to intrinsic circulating anticoagulants
 Hematopoietic 1.06 0.834 – 1.34 0.642 72 797 exclusion phecode
286.7 Other and unspecified coagulation defects Hematopoietic 0.999 0.894 – 1.12 0.986 346 3660 exclusion phecode
287 Purpura and other hemorrhagic conditions Hematopoietic 1.01 0.953 – 1.06 0.838 1469 15512 exclusion phecode
287.1 Spontaneous ecchymoses Hematopoietic 1.04 0.855 – 1.26 0.717 111 1211 exclusion phecode
287.2 Allergic purpura Hematopoietic 0.992 0.741 – 1.33 0.96 45 486 exclusion phecode
287.3 Thrombocytopenia Hematopoietic 1.01 0.951 – 1.06 0.85 1383 14596 exclusion phecode
287.31 Primary thrombocytopenia Hematopoietic 1.09 0.983 – 1.22 0.098 374 3961 exclusion phecode
287.32 Secondary thrombocytopenia Hematopoietic 0.896 0.688 – 1.17 0.417 65 710 exclusion phecode
288 Diseases of white blood cells Hematopoietic 1.02 0.981 – 1.05 0.385 3503 35525 exclusion phecode
288.1 Decreased white blood cell count Hematopoietic 1.01 0.974 – 1.05 0.547 2964 29932 exclusion phecode
288.11 Neutropenia Hematopoietic 1.01 0.974 – 1.05 0.555 2971 30014 exclusion phecode
288.3 Eosinophilia Hematopoietic 1.05 0.822 – 1.35 0.676 62 663 exclusion phecode
289 Other diseases of blood and blood-forming organs Hematopoietic 0.992 0.921 – 1.07 0.839 774 8112 exclusion phecode
289.3
Personal history of diseases of blood and
Personal history of diseases of blood and blood-forming organs
 Hematopoietic 1.05 0.922 – 1.19 0.461 259 2760 exclusion phecode
289.4 Lymphadenitis Hematopoietic 0.988 0.947 – 1.03 0.573 2355 24586 exclusion phecode
289.5 Diseases of spleen Hematopoietic 0.985 0.893 – 1.09 0.763 434 4831 exclusion phecode
289.8 Polycythemia, secondary Hematopoietic 1.03 0.903 – 1.17 0.683 254 2705 exclusion phecode
289.9 Abnormality of red blood cells Hematopoietic 0.828 0.654 – 1.05 0.117 76 842 exclusion phecode
290
Delirium dementia and amnestic and other
Delirium dementia and amnestic and other cognitive disorders
 Mental Disorders 0.954 0.907 – 1 0.0666 1641 17903 exclusion phecode
290.1 Dementias Mental Disorders 0.94 0.877 – 1.01 0.0849 857 9276 exclusion phecode
290.11 Alzheimer's disease Mental Disorders 0.92 0.828 – 1.02 0.123 386 3981 exclusion phecode
290.16 Vascular dementia Mental Disorders 0.93 0.788 – 1.1 0.388 152 1848 exclusion phecode
290.2 Delirium due to conditions classified elsewhere Mental Disorders 0.977 0.895 – 1.07 0.602 539 6035 exclusion phecode
290.3
Other persistent mental disorders due to
Other persistent mental disorders due to conditions classified elsewhere
 Mental Disorders 1.14 0.895 – 1.46 0.283 66 689 exclusion phecode
291
Other specified nonpsychotic and/or transient
Other specified nonpsychotic and/or transient mental disorders
 Mental Disorders 1.03 0.95 – 1.11 0.521 722 7929 exclusion phecode
291.1
Transient mental disorders due to conditions
Transient mental disorders due to conditions classified elsewhere
 Mental Disorders 0.95 0.784 – 1.15 0.597 113 1266 exclusion phecode
291.4
Specific nonpsychotic mental disorders due to
Specific nonpsychotic mental disorders due to brain damage
 Mental Disorders 0.992 0.874 – 1.13 0.902 252 2680 exclusion phecode
291.8 Alteration of consciousness Mental Disorders 1.09 0.976 – 1.21 0.132 373 4141 exclusion phecode
292 Neurological disorders Mental Disorders 0.981 0.95 – 1.01 0.253 3987 43204 exclusion phecode
292.1 Aphasia/speech disturbance Mental Disorders 1.02 0.963 – 1.08 0.51 1287 14150 exclusion phecode
292.2 Mild cognitive impairment Mental Disorders 0.967 0.827 – 1.13 0.671 159 1770 exclusion phecode
292.3 Memory loss Mental Disorders 0.934 0.861 – 1.01 0.0963 644 6520 exclusion phecode
292.4 Altered mental status Mental Disorders 0.965 0.919 – 1.01 0.143 1820 20305 exclusion phecode
292.6 Hallucinations Mental Disorders 1.06 0.938 – 1.2 0.355 269 2892 exclusion phecode
293 Symptoms involving head and neck Mental Disorders 1.01 0.96 – 1.06 0.788 1873 19540 exclusion phecode
293.1
Swelling, mass, or lump in head and neck
Swelling, mass, or lump in head and neck [Space-occupying lesion, intracranial NOS]
 Mental Disorders 0.986 0.918 – 1.06 0.702 831 8486 exclusion phecode
295 Schizophrenia and other psychotic disorders Mental Disorders 1.02 0.945 – 1.1 0.621 730 8042 exclusion phecode
295.1 Schizophrenia Mental Disorders 0.989 0.902 – 1.08 0.808 495 5507 exclusion phecode
295.2 Paranoid disorders Mental Disorders 1.07 0.907 – 1.26 0.422 152 1690 exclusion phecode
295.3 Psychosis Mental Disorders 1.08 0.924 – 1.27 0.322 155 1622 exclusion phecode
296 Mood disorders Mental Disorders 0.994 0.975 – 1.01 0.571 11154 118283 exclusion phecode
296.1 Bipolar Mental Disorders 0.907 0.849 – 0.969 0.00375 949 10113 exclusion phecode
296.2 Depression Mental Disorders 1 0.981 – 1.02 0.941 10575 112246 exclusion phecode
296.22 Major depressive disorder Mental Disorders 0.949 0.847 – 1.06 0.366 317 3450 exclusion phecode
297.2 Suicide or self-inflicted injury Mental Disorders 1.04 0.921 – 1.17 0.544 276 2948 exclusion phecode
300 Anxiety disorders Mental Disorders 0.985 0.959 – 1.01 0.242 6285 65322 exclusion phecode
300.1 Anxiety disorder Mental Disorders 0.983 0.957 – 1.01 0.208 5813 60361 exclusion phecode
300.11 Generalized anxiety disorder Mental Disorders 0.927 0.777 – 1.1 0.396 137 1422 exclusion phecode
300.12 Agorophobia, social phobia, and panic disorder Mental Disorders 0.992 0.916 – 1.07 0.845 650 6752 exclusion phecode
300.13 Phobia Mental Disorders 0.971 0.882 – 1.07 0.557 453 4783 exclusion phecode
300.3 Obsessive-compulsive disorders Mental Disorders 1.01 0.849 – 1.2 0.903 131 1352 exclusion phecode
300.4 Dysthymic disorder Mental Disorders 1.09 0.816 – 1.45 0.568 47 498 exclusion phecode
300.8 Acute reaction to stress Mental Disorders 1.02 0.84 – 1.23 0.857 112 1186 exclusion phecode
300.9 Posttraumatic stress disorder Mental Disorders 0.894 0.729 – 1.1 0.279 102 1082 exclusion phecode
301 Personality disorders Mental Disorders 1.01 0.896 – 1.14 0.85 276 3211 exclusion phecode
301.2 Antisocial/borderline personality disorder Mental Disorders 1 0.821 – 1.22 0.978 100 1151 exclusion phecode
302 Sexual and gender identity disorders Mental Disorders 1.11 0.966 – 1.27 0.142 231 2630 exclusion phecode
303 Psychogenic and somatoform disorders Mental Disorders 1 0.91 – 1.11 0.951 437 4460 exclusion phecode
303.3 Psychogenic disorder Mental Disorders 1.03 0.925 – 1.16 0.552 333 3341 exclusion phecode
303.4 Somatoform disorder Mental Disorders 1.04 0.856 – 1.26 0.707 110 1186 exclusion phecode
304 Adjustment reaction Mental Disorders 0.916 0.808 – 1.04 0.171 263 2829 exclusion phecode
305.2 Eating disorder Mental Disorders 1.03 0.826 – 1.28 0.793 80 868 exclusion phecode
306 Other mental disorder Mental Disorders 1.02 1.01 – 1.04 0.00136 24886 217816 exclusion phecode
306.9 Tension headache Mental Disorders 1.01 0.896 – 1.14 0.864 289 3047 exclusion phecode
313 Pervasive developmental disorders Mental Disorders 0.769 0.601 – 0.985 0.0376 63 732 exclusion phecode
313.3 Autism Mental Disorders 0.65 0.478 – 0.885 0.00612 42 511 exclusion phecode
315 Develomental delays and disorders Mental Disorders 1.04 0.929 – 1.17 0.467 302 3293 exclusion phecode
315.1 Learning disorder Mental Disorders 0.887 0.739 – 1.07 0.2 125 1539 exclusion phecode
315.2 Speech and language disorder Mental Disorders 0.947 0.753 – 1.19 0.643 76 806 exclusion phecode
316 Substance addiction and disorders Mental Disorders 1.01 0.984 – 1.04 0.363 4802 50004 exclusion phecode
316.1 Polyneuropathy due to drugs Mental Disorders 0.9 0.699 – 1.16 0.413 55 568 exclusion phecode
317 Alcohol-related disorders Mental Disorders 1.01 0.991 – 1.03 0.291 11642 119575 exclusion phecode
317.1 Alcoholism Mental Disorders 0.999 0.976 – 1.02 0.92 8145 83748 exclusion phecode
317.11 Alcoholic liver damage Mental Disorders 0.977 0.903 – 1.06 0.553 674 7891 exclusion phecode
318 Tobacco use disorder Mental Disorders 1.05 1.03 – 1.06 1.76e-08 17504 175090 exclusion phecode
320 Meningitis Neurological 0.992 0.897 – 1.1 0.869 413 4228 exclusion phecode
323 Encephalitis Neurological 1.01 0.899 – 1.13 0.904 320 3246 exclusion phecode
323.2 Acute (transverse) myelitis Neurological 0.918 0.72 – 1.17 0.491 69 704 exclusion phecode
324 Other CNS infection and poliomyelitis Neurological 0.974 0.858 – 1.11 0.686 265 2741 exclusion phecode
327 Sleep disorders Neurological 1.01 0.948 – 1.08 0.736 991 10938 exclusion phecode
327.3 Sleep apnea Neurological 1.05 1.01 – 1.09 0.00606 3577 41582 exclusion phecode
327.4 Insomnia Neurological 0.891 0.756 – 1.05 0.169 147 1575 exclusion phecode
327.41 Organic or persistent insomnia Neurological 0.92 0.768 – 1.1 0.369 125 1325 exclusion phecode
331 Other cerebral degenerations Neurological 0.957 0.897 – 1.02 0.183 1005 10696 exclusion phecode
331.1 Hydrocephalus Neurological 0.98 0.89 – 1.08 0.674 464 4760 exclusion phecode
331.9 Cerebral degeneration, unspecified Neurological 0.906 0.813 – 1.01 0.0723 356 4011 exclusion phecode
332 Parkinson's disease Neurological 0.944 0.886 – 1.01 0.076 1036 10429 exclusion phecode
333
Extrapyramidal disease and abnormal movement
Extrapyramidal disease and abnormal movement disorders
 Neurological 0.987 0.918 – 1.06 0.723 802 8440 exclusion phecode
333.1 Essential tremor Neurological 0.961 0.83 – 1.11 0.601 187 2008 exclusion phecode
333.2 Myoclonus Neurological 1.19 0.959 – 1.47 0.115 86 910 exclusion phecode
333.4 Torsion dystonia Neurological 0.992 0.867 – 1.14 0.909 233 2398 exclusion phecode
334 Degenerative disease of the spinal cord Neurological 1.04 0.986 – 1.09 0.16 1634 17019 exclusion phecode
334.1 Spinocerebellar disease Neurological 0.937 0.769 – 1.14 0.516 107 1105 exclusion phecode
334.2 Anterior horn cell disease Neurological 1.06 0.924 – 1.22 0.405 221 2292 exclusion phecode
335 Multiple sclerosis Neurological 0.965 0.911 – 1.02 0.229 1260 12798 exclusion phecode
337 Disorders of the autonomic nervous system Neurological 1.05 0.921 – 1.21 0.443 228 2499 exclusion phecode
337.1 Peripheral autonomic neuropathy Neurological 1.04 0.802 – 1.36 0.748 59 669 exclusion phecode
338 Pain Neurological 1.04 0.967 – 1.13 0.271 699 7279 exclusion phecode
338.1 Acute pain Neurological 1.02 0.921 – 1.14 0.656 356 3713 exclusion phecode
338.2 Chronic pain Neurological 1.06 0.947 – 1.18 0.33 349 3627 exclusion phecode
339 Other headache syndromes Neurological 1.03 1.01 – 1.06 0.0112 7225 74386 exclusion phecode
340 Migraine Neurological 0.982 0.944 – 1.02 0.372 2697 27382 exclusion phecode
340.1 Migrain with aura Neurological 0.837 0.724 – 0.967 0.016 200 2024 exclusion phecode
341
Other demyelinating diseases of central nervous
Other demyelinating diseases of central nervous system
 Neurological 1.02 0.89 – 1.16 0.817 234 2434 exclusion phecode
342 Hemiplegia Neurological 1.06 1 – 1.12 0.0396 1275 14011 exclusion phecode
343 Infantile cerebral palsy Neurological 1.05 0.881 – 1.25 0.595 132 1366 exclusion phecode
344 Other paralytic syndromes Neurological 1.04 0.952 – 1.13 0.415 590 6208 exclusion phecode
345 Epilepsy, recurrent seizures, convulsions Neurological 0.991 0.961 – 1.02 0.556 4610 47531 exclusion phecode
345.1 Epilepsy Neurological 0.993 0.923 – 1.07 0.844 791 8226 exclusion phecode
345.11 Generalized convulsive epilepsy Neurological 1.05 0.947 – 1.16 0.362 395 4182 exclusion phecode
345.12 Partial epilepsy Neurological 0.95 0.836 – 1.08 0.428 259 2640 exclusion phecode
345.3 Convulsions Neurological 0.989 0.945 – 1.04 0.64 2042 21119 exclusion phecode
346.1
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of skull and head
 Neurological 1.1 0.917 – 1.33 0.295 127 1338 exclusion phecode
348 Other conditions of brain Neurological 1.04 0.961 – 1.12 0.335 678 7378 exclusion phecode
348.2 Cerebral edema and compression of brain Neurological 1.01 0.892 – 1.16 0.823 238 2553 exclusion phecode
348.4 Cerebral cysts Neurological 0.901 0.749 – 1.08 0.272 120 1284 exclusion phecode
348.7 Coma Neurological 1.02 0.91 – 1.14 0.751 330 3373 exclusion phecode
348.8 Encephalopathy, not elsewhere classified Neurological 1.1 0.956 – 1.27 0.178 208 2345 exclusion phecode
348.9 Other conditions of brain, NOS Neurological 0.926 0.83 – 1.03 0.168 346 3702 exclusion phecode
349
Other and unspecified disorders of the nervous
Other and unspecified disorders of the nervous system
 Neurological 1 0.893 – 1.13 0.958 302 3234 exclusion phecode
350 Abnormal movement Neurological 0.967 0.926 – 1.01 0.119 2322 25008 exclusion phecode
350.1 Abnormal involuntary movements Neurological 0.965 0.898 – 1.04 0.334 799 8332 exclusion phecode
350.2 Abnormality of gait Neurological 0.939 0.887 – 0.993 0.0263 1358 14903 exclusion phecode
350.3 Lack of coordination Neurological 1.03 0.915 – 1.15 0.668 316 3416 exclusion phecode
350.6 Disturbances of sensation of smell and taste Neurological 0.943 0.699 – 1.27 0.698 50 508 exclusion phecode
351 Other peripheral nerve disorders Neurological 1.05 1.03 – 1.07 1.23e-06 11191 118192 exclusion phecode
352 Disorders of other cranial nerves Neurological 1.01 0.956 – 1.07 0.655 1234 12993 exclusion phecode
352.1 Trigeminal nerve disorders [CN5] Neurological 1.03 0.934 – 1.14 0.528 435 4427 exclusion phecode
352.2 Facial nerve disorders [CN7] Neurological 1.02 0.946 – 1.1 0.63 776 8326 exclusion phecode
353 Nerve root and plexus disorders Neurological 1.05 0.988 – 1.12 0.108 1036 10700 exclusion phecode
353.1 Nerve plexus lesions Neurological 1.11 0.913 – 1.34 0.303 109 1084 exclusion phecode
353.2 Nerve root lesions Neurological 1.07 0.806 – 1.42 0.639 52 533 exclusion phecode
356 Hereditary and idiopathic peripheral neuropathy Neurological 0.887 0.741 – 1.06 0.192 137 1416 exclusion phecode
357 Inflammatory and toxic neuropathy Neurological 1.05 0.984 – 1.11 0.149 1068 12730 exclusion phecode
358 Myoneural disorders Neurological 0.976 0.84 – 1.13 0.746 190 1980 exclusion phecode
358.1 Myasthenia gravis Neurological 0.999 0.856 – 1.17 0.987 172 1804 exclusion phecode
359 Muscular dystrophies and other myopathies Neurological 1.01 0.916 – 1.12 0.799 400 4400 exclusion phecode
359.1 Muscular dystrophies Neurological 0.988 0.82 – 1.19 0.897 116 1151 exclusion phecode
359.2 Myopathy Neurological 1.01 0.899 – 1.14 0.848 299 3404 exclusion phecode
360 Disorders of the globe Sense Organs 0.96 0.853 – 1.08 0.498 312 3184 exclusion phecode
360.2 Progressive myopia Sense Organs 0.976 0.85 – 1.12 0.736 235 2374 exclusion phecode
361 Retinal detachments and defects Sense Organs 0.987 0.951 – 1.02 0.498 3031 30390 exclusion phecode
361.1 Retinal detachment with retinal defect Sense Organs 0.984 0.93 – 1.04 0.589 1306 13014 exclusion phecode
361.2 Retinoschisis and retinal cysts Sense Organs 0.856 0.66 – 1.11 0.242 60 639 exclusion phecode
362 Other retinal disorders Sense Organs 0.98 0.945 – 1.02 0.268 3251 35990 exclusion phecode
362.2
Degeneration of macula and posterior pole of
Degeneration of macula and posterior pole of retina
 Sense Organs 0.958 0.914 – 1 0.075 1902 20471 exclusion phecode
362.29 Macular degeneration (senile) of retina NOS Sense Organs 0.958 0.914 – 1 0.0759 1900 20441 exclusion phecode
362.3 Other nondiabetic retinopathy Sense Organs 1.11 0.929 – 1.34 0.242 127 1516 exclusion phecode
362.31 Separation of retinal layers Sense Organs 1.22 0.984 – 1.51 0.0696 92 926 exclusion phecode
362.4 Retinal vascular changes and abnomalities Sense Organs 1 0.926 – 1.08 0.97 700 7915 exclusion phecode
362.6 Peripheral retinal degenerations Sense Organs 0.905 0.773 – 1.06 0.218 166 1712 exclusion phecode
362.7 Hereditary retinal dystrophies Sense Organs 0.951 0.752 – 1.2 0.671 79 773 exclusion phecode
362.8 Retinal hemorrhage/ischemia Sense Organs 1.05 0.852 – 1.29 0.663 102 1090 exclusion phecode
363
Chorioretinal inflammations, scars, and other
Chorioretinal inflammations, scars, and other disorders of choroid
 Sense Organs 0.867 0.732 – 1.03 0.0996 150 1614 exclusion phecode
363.3 Chorioretinal scars Sense Organs 0.745 0.56 – 0.991 0.0428 53 661 exclusion phecode
364 Corneal opacity and other disorders of cornea Sense Organs 0.926 0.851 – 1.01 0.0721 587 6070 exclusion phecode
364.1 Corneal opacity Sense Organs 1.1 0.884 – 1.38 0.387 81 847 exclusion phecode
364.2 Corneal edema Sense Organs 1.03 0.806 – 1.33 0.789 71 741 exclusion phecode
364.4 Corneal degenerations Sense Organs 0.949 0.812 – 1.11 0.513 173 1891 exclusion phecode
364.41 Keratoconus Sense Organs 0.868 0.691 – 1.09 0.226 81 824 exclusion phecode
364.5 Corneal dystrophy Sense Organs 0.888 0.77 – 1.03 0.105 198 1990 exclusion phecode
364.9 Cornea replaced by transplant Sense Organs 0.992 0.806 – 1.22 0.937 93 939 exclusion phecode
365 Glaucoma Sense Organs 1.03 1 – 1.07 0.0516 3986 41133 exclusion phecode
365.1 Open-angle glaucoma Sense Organs 1.04 0.977 – 1.12 0.2 938 9624 exclusion phecode
365.11 Primary open angle glaucoma Sense Organs 1.04 0.976 – 1.12 0.213 932 9574 exclusion phecode
365.2 Primary angle-closure glaucoma Sense Organs 0.941 0.868 – 1.02 0.138 649 6579 exclusion phecode
366 Cataract Sense Organs 1.02 1 – 1.03 0.0221 17642 158330 exclusion phecode
366.1 Nonsenile Cataract Sense Organs 0.924 0.717 – 1.19 0.541 65 669 exclusion phecode
366.2 Senile cataract Sense Organs 1.01 0.988 – 1.04 0.319 7293 76693 exclusion phecode
366.3 Traumatic cataract Sense Organs 0.791 0.643 – 0.973 0.0263 94 928 exclusion phecode
367
Disorders of refraction and accommodation
Disorders of refraction and accommodation; blindness and low vision
 Sense Organs 0.986 0.943 – 1.03 0.543 2194 22670 exclusion phecode
367.1 Myopia Sense Organs 1.02 0.955 – 1.08 0.628 1159 11766 exclusion phecode
367.2 Astigmatism Sense Organs 1.11 0.95 – 1.3 0.183 178 1793 exclusion phecode
367.8 Hypermetropia Sense Organs 0.992 0.866 – 1.14 0.911 241 2395 exclusion phecode
367.9 Blindness and low vision Sense Organs 0.906 0.833 – 0.986 0.0215 616 6764 exclusion phecode
368 Visual disturbances Sense Organs 1.01 0.966 – 1.05 0.804 2668 27947 exclusion phecode
368.1 Amblyopia Sense Organs 0.95 0.863 – 1.05 0.295 465 4962 exclusion phecode
368.2 Diplopia and disorders of binocular vision Sense Organs 0.997 0.919 – 1.08 0.933 658 6893 exclusion phecode
368.3 Anisometropia Sense Organs 0.989 0.826 – 1.18 0.901 145 1440 exclusion phecode
368.4 Visual field defects Sense Organs 1.01 0.897 – 1.14 0.846 288 3118 exclusion phecode
368.9 Subjective visual disturbances Sense Organs 1.04 0.949 – 1.13 0.425 559 5794 exclusion phecode
369 Infection of the eye Sense Organs 0.94 0.859 – 1.03 0.185 508 5221 exclusion phecode
369.2 Eye infection, viral Sense Organs 0.824 0.683 – 0.994 0.0427 117 1175 exclusion phecode
369.5 Conjunctivitis, infectious Sense Organs 0.904 0.782 – 1.05 0.175 194 2013 exclusion phecode
370 Keratitis Sense Organs 0.892 0.786 – 1.01 0.0773 255 2702 exclusion phecode
370.1 Corneal ulcer Sense Organs 0.764 0.638 – 0.915 0.00352 127 1334 exclusion phecode
371 Inflammation of the eye Sense Organs 0.994 0.957 – 1.03 0.763 2863 28793 exclusion phecode
371.1 Uveitis, noninfectious or NOS Sense Organs 1.02 0.922 – 1.12 0.731 436 4569 exclusion phecode
371.3 Inflammation of eyelids Sense Organs 0.991 0.949 – 1.04 0.698 2236 22240 exclusion phecode
372 Disorders of conjunctiva Sense Organs 0.996 0.921 – 1.08 0.923 707 7142 exclusion phecode
374 Other disorders of eyelids Sense Organs 1.02 0.992 – 1.05 0.161 5212 53459 exclusion phecode
374.1 Ectropion or entropion Sense Organs 0.983 0.921 – 1.05 0.618 951 9879 exclusion phecode
374.3 Ptosis of eyelid Sense Organs 0.994 0.945 – 1.04 0.802 1675 17171 exclusion phecode
375 Disorders of lacrimal system Sense Organs 1.04 0.991 – 1.09 0.114 2031 20754 exclusion phecode
375.2 Epiphora Sense Organs 1.02 0.949 – 1.09 0.603 826 8400 exclusion phecode
376 Disorders of the orbit Sense Organs 0.845 0.673 – 1.06 0.146 78 807 exclusion phecode
377 Disorders of optic nerve and visual pathways Sense Organs 1.14 1.02 – 1.28 0.0267 327 3423 exclusion phecode
377.1 Optic atrophy Sense Organs 1.01 0.743 – 1.37 0.963 50 535 exclusion phecode
377.3 Optic neuritis/neuropathy Sense Organs 1.14 0.938 – 1.37 0.192 115 1197 exclusion phecode
378
Strabismus and other disorders of binocular eye
Strabismus and other disorders of binocular eye movements
 Sense Organs 0.984 0.929 – 1.04 0.572 1294 13387 exclusion phecode
378.1 Strabismus (not specified as paralytic) Sense Organs 0.984 0.917 – 1.06 0.66 854 8629 exclusion phecode
378.2 Nystagmus and other irregular eye movements Sense Organs 1.04 0.89 – 1.2 0.654 188 2006 exclusion phecode
378.5 Paralytic strabismus Sense Organs 0.972 0.853 – 1.11 0.673 243 2625 exclusion phecode
379 Other disorders of eye Sense Organs 1.01 0.969 – 1.04 0.782 3229 34624 exclusion phecode
379.2 Disorders of vitreous body Sense Organs 1.01 0.954 – 1.08 0.646 1155 12781 exclusion phecode
379.3 Aphakia and other disorders of lens Sense Organs 1.01 0.959 – 1.06 0.702 1597 16868 exclusion phecode
379.4 Anomalies of pupillary function Sense Organs 1.07 0.842 – 1.36 0.578 69 668 exclusion phecode
379.5 Disorders of iris and ciliary body Sense Organs 1.01 0.906 – 1.12 0.875 357 3776 exclusion phecode
379.9 Pain, swelling or discharge of eye Sense Organs 1.02 0.865 – 1.2 0.824 150 1609 exclusion phecode
380 Disorders of external ear Sense Organs 1.06 0.976 – 1.16 0.16 581 6004 exclusion phecode
380.1 Otitis externa Sense Organs 1.05 0.952 – 1.15 0.337 439 4850 exclusion phecode
380.4 Impacted cerumen Sense Organs 1.16 1.04 – 1.3 0.0099 332 3387 exclusion phecode
381 Otitis media and Eustachian tube disorders Sense Organs 1.06 1.01 – 1.11 0.0137 1970 20237 exclusion phecode
381.1 Otitis media Sense Organs 1.08 1.03 – 1.14 0.00241 1609 16620 exclusion phecode
381.11 Suppurative and unspecified otitis media Sense Organs 1.11 1.03 – 1.2 0.00497 781 8014 exclusion phecode
381.2 Eustachian tube disorders Sense Organs 1 0.865 – 1.16 0.977 185 1831 exclusion phecode
381.3 Mastoiditis & related conditions Sense Organs 1.02 0.867 – 1.21 0.783 152 1613 exclusion phecode
381.9 Otorrhea Sense Organs 1.06 0.932 – 1.21 0.371 254 2647 exclusion phecode
382 Otalgia Sense Organs 0.954 0.845 – 1.08 0.451 286 2916 exclusion phecode
383 Otosclerosis Sense Organs 0.873 0.775 – 0.983 0.0249 299 2952 exclusion phecode
384 Other disorders of tympanic membrane Sense Organs 1.05 0.987 – 1.11 0.125 1212 12284 exclusion phecode
384.4 Perforation of tympanic membrane Sense Organs 1.06 0.991 – 1.13 0.0881 975 9877 exclusion phecode
385 Other disorders of middle ear and mastoid Sense Organs 1.07 0.992 – 1.16 0.0791 727 7369 exclusion phecode
385.3 Cholesteatoma Sense Organs 1.08 0.988 – 1.17 0.0903 562 5687 exclusion phecode
385.5
Tympanosclerosis and middle ear disease related
Tympanosclerosis and middle ear disease related to otitis media
 Sense Organs 1.11 0.969 – 1.27 0.131 225 2279 exclusion phecode
386
Vertiginous syndromes and other disorders of
Vertiginous syndromes and other disorders of vestibular system
 Sense Organs 0.971 0.923 – 1.02 0.266 1614 16424 exclusion phecode
386.1 Meniere's disease Sense Organs 0.968 0.887 – 1.06 0.465 544 5454 exclusion phecode
386.2 Peripheral or central vertigo Sense Organs 0.923 0.827 – 1.03 0.158 344 3533 exclusion phecode
386.3 Labyrinthitis Sense Organs 0.992 0.919 – 1.07 0.847 708 7253 exclusion phecode
386.9
Dizziness and giddiness (Light-headedness and
Dizziness and giddiness (Light-headedness and vertigo)
 Sense Organs 1.01 0.976 – 1.04 0.633 4162 43123 exclusion phecode
388 Other disorders of ear Sense Organs 1.03 0.89 – 1.2 0.683 186 1909 exclusion phecode
389 Hearing loss Sense Organs 0.991 0.958 – 1.02 0.599 3771 39261 exclusion phecode
389.1 Sensorineural hearing loss Sense Organs 1.08 0.98 – 1.2 0.116 408 4262 exclusion phecode
389.2 Conductive hearing loss Sense Organs 0.989 0.893 – 1.1 0.834 416 4232 exclusion phecode
389.4 Tinnitus Sense Organs 1.02 0.924 – 1.12 0.745 479 4815 exclusion phecode
394 Rheumatic disease of the heart valves Circulatory System 0.983 0.953 – 1.01 0.275 4358 45542 exclusion phecode
394.2 Mitral valve disease Circulatory System 0.984 0.946 – 1.02 0.429 2682 27877 exclusion phecode
394.3 Aortic valve disease Circulatory System 0.999 0.939 – 1.06 0.971 1134 11851 exclusion phecode
394.7 Disease of tricuspid valve Circulatory System 0.956 0.893 – 1.02 0.192 929 9798 exclusion phecode
395 Heart valve disorders Circulatory System 0.989 0.957 – 1.02 0.532 3742 39314 exclusion phecode
395.1 Nonrheumatic mitral valve disorders Circulatory System 0.983 0.944 – 1.02 0.395 2588 26939 exclusion phecode
395.2 Nonrheumatic aortic valve disorders Circulatory System 1.06 0.922 – 1.21 0.43 229 2553 exclusion phecode
395.3 Nonrheumatic tricuspid valve disorders Circulatory System 0.972 0.789 – 1.2 0.791 89 963 exclusion phecode
395.4 Nonrheumatic pulmonary valve disorders Circulatory System 1 0.806 – 1.24 1 85 899 exclusion phecode
395.6 Heart valve replaced Circulatory System 0.987 0.933 – 1.05 0.664 1308 13910 exclusion phecode
396 Abnormal heart sounds Circulatory System 1.06 0.991 – 1.13 0.0896 955 9935 exclusion phecode
401 Hypertension Circulatory System 1.08 1.07 – 1.09 5.04e-58 63455 258352 exclusion phecode
401.1 Essential hypertension Circulatory System 1.08 1.07 – 1.09 2.03e-58 63258 258135 exclusion phecode
401.2 Hypertensive heart and/or renal disease Circulatory System 1.03 0.974 – 1.09 0.297 1356 18130 exclusion phecode
401.21 Hypertensive heart disease Circulatory System 1.02 0.902 – 1.15 0.768 287 3498 exclusion phecode
401.22 Hypertensive chronic kidney disease Circulatory System 1.03 0.965 – 1.09 0.407 1072 14761 exclusion phecode
401.3 Other hypertensive complications Circulatory System 1.04 0.868 – 1.25 0.65 121 1384 exclusion phecode
402
Elevated blood pressure reading without
Elevated blood pressure reading without diagnosis of hypertension
 Circulatory System 1.12 1.06 – 1.18 0.000104 1324 14232 exclusion phecode
411 Ischemic Heart Disease Circulatory System 1.05 1.04 – 1.07 2.01e-15 26474 199521 exclusion phecode
411.1 Unstable angina (intermediate coronary syndrome) Circulatory System 1.04 1 – 1.07 0.0269 4203 48355 exclusion phecode
411.2 Myocardial infarction Circulatory System 1.07 1.05 – 1.09 1.99e-10 10031 105611 exclusion phecode
411.3 Angina pectoris Circulatory System 1.05 1.03 – 1.07 1.21e-08 13082 135305 exclusion phecode
411.4 Coronary atherosclerosis Circulatory System 1.06 1.04 – 1.08 4.67e-12 17076 145560 exclusion phecode
411.41 Aneurysm and dissection of heart Circulatory System 0.94 0.867 – 1.02 0.129 654 6607 exclusion phecode
411.8
Other chronic ischemic heart disease
Other chronic ischemic heart disease, unspecified
 Circulatory System 1.06 1.04 – 1.08 8.54e-09 12341 123757 exclusion phecode
411.9
Other acute and subacute forms of ischemic
Other acute and subacute forms of ischemic heart disease
 Circulatory System 1.11 1.04 – 1.18 0.00139 1039 11418 exclusion phecode
414 Other forms of chronic heart disease Circulatory System 1.03 0.982 – 1.09 0.202 1503 17064 exclusion phecode
414.2 ASCVD Circulatory System 0.924 0.704 – 1.21 0.567 56 673 exclusion phecode
415 Pulmonary heart disease Circulatory System 1 0.973 – 1.04 0.788 4049 41907 exclusion phecode
415.11 Pulmonary embolism and infarction, acute Circulatory System 0.984 0.767 – 1.26 0.9 70 698 exclusion phecode
415.2 Chronic pulmonary heart disease Circulatory System 0.978 0.893 – 1.07 0.635 502 5580 exclusion phecode
415.21 Primary pulmonary hypertension Circulatory System 1.04 0.936 – 1.16 0.463 372 4175 exclusion phecode
416 Cardiomegaly Circulatory System 1.06 1.02 – 1.11 0.00537 2238 24840 exclusion phecode
418 Nonspecific chest pain Circulatory System 1.03 1.02 – 1.04 6.05e-06 25725 255784 exclusion phecode
418.1 Precordial pain Circulatory System 1.06 1.02 – 1.1 0.00278 3162 33658 exclusion phecode
420 Carditis Circulatory System 0.934 0.891 – 0.98 0.00532 1865 19658 exclusion phecode
420.1 Myocarditis Circulatory System 0.877 0.727 – 1.06 0.167 121 1184 exclusion phecode
420.2 Pericarditis Circulatory System 0.932 0.878 – 0.989 0.0209 1199 12513 exclusion phecode
420.21 Acute pericarditis Circulatory System 0.948 0.822 – 1.09 0.466 200 2095 exclusion phecode
420.22 Chronic pericarditis Circulatory System 0.91 0.749 – 1.1 0.339 102 1038 exclusion phecode
420.3 Endocarditis Circulatory System 0.956 0.88 – 1.04 0.28 621 6684 exclusion phecode
425 Cardiomyopathy Circulatory System 1.03 0.964 – 1.09 0.415 1106 11797 exclusion phecode
425.1 Primary/intrinsic cardiomyopathies Circulatory System 1.02 0.962 – 1.09 0.447 1076 11476 exclusion phecode
425.11 Hypertrophic obstructive cardiomyopathy Circulatory System 0.993 0.826 – 1.19 0.939 123 1239 exclusion phecode
425.12 Other hypertrophic cardiomyopathy Circulatory System 0.84 0.709 – 0.994 0.0424 153 1515 exclusion phecode
425.8 Other cardiomyopathy Circulatory System 0.824 0.623 – 1.09 0.172 53 557 exclusion phecode
426 Cardiac conduction disorders Circulatory System 1 0.976 – 1.03 0.839 5951 64423 exclusion phecode
426.2 Atrioventricular [AV] block Circulatory System 1 0.953 – 1.05 0.999 1783 19598 exclusion phecode
426.21 First degree AV block Circulatory System 1.01 0.938 – 1.08 0.844 824 9130 exclusion phecode
426.23 Second degree AV block Circulatory System 1.03 0.928 – 1.14 0.588 387 4169 exclusion phecode
426.24 Atrioventricular block, complete Circulatory System 0.948 0.864 – 1.04 0.253 491 5429 exclusion phecode
426.25 Other heart block Circulatory System 0.978 0.812 – 1.18 0.817 121 1215 exclusion phecode
426.3 Bundle branch block Circulatory System 1.01 0.973 – 1.05 0.592 2874 31064 exclusion phecode
426.31 Right bundle branch block Circulatory System 0.987 0.932 – 1.04 0.646 1303 13843 exclusion phecode
426.32 Left bundle branch block Circulatory System 1.04 0.987 – 1.1 0.136 1487 16322 exclusion phecode
426.4 Anomalous atrioventricular excitation Circulatory System 0.962 0.839 – 1.1 0.579 224 2201 exclusion phecode
426.8 Other cardiac conduction disorders Circulatory System 0.9 0.676 – 1.2 0.473 55 564 exclusion phecode
426.9 Cardiac pacemaker/device in situ Circulatory System 1 0.957 – 1.05 0.955 2065 23036 exclusion phecode
426.91 Cardiac pacemaker in situ Circulatory System 0.992 0.946 – 1.04 0.748 1901 21148 exclusion phecode
427 Cardiac dysrhythmias Circulatory System 1 0.989 – 1.02 0.661 21632 193998 exclusion phecode
427.1 Paroxysmal tachycardia, unspecified Circulatory System 1.03 0.99 – 1.07 0.146 2884 30138 exclusion phecode
427.11 Paroxysmal supraventricular tachycardia Circulatory System 1.02 0.977 – 1.07 0.356 2122 22187 exclusion phecode
427.12 Paroxysmal ventricular tachycardia Circulatory System 1.08 1 – 1.16 0.0437 828 8689 exclusion phecode
427.2 Atrial fibrillation and flutter Circulatory System 1 0.984 – 1.02 0.799 12898 124582 exclusion phecode
427.3 Other specified cardiac dysrhythmias Circulatory System 1.01 0.974 – 1.05 0.54 2910 30189 exclusion phecode
427.4 Cardiac arrest and ventricular fibrillation Circulatory System 1.01 0.947 – 1.08 0.776 1038 11070 exclusion phecode
427.41 Ventricular fibrillation and flutter Circulatory System 1.01 0.894 – 1.13 0.917 306 3215 exclusion phecode
427.42 Cardiac arrest Circulatory System 1.01 0.944 – 1.09 0.722 859 9182 exclusion phecode
427.5 Arrhythmia (cardiac) NOS Circulatory System 0.964 0.899 – 1.03 0.304 847 8931 exclusion phecode
427.6 Premature beats Circulatory System 1.01 0.917 – 1.1 0.906 495 5046 exclusion phecode
427.61 Supraventricular premature beats Circulatory System 1.01 0.831 – 1.22 0.958 110 1092 exclusion phecode
427.7 Tachycardia NOS Circulatory System 0.992 0.947 – 1.04 0.732 1922 20648 exclusion phecode
427.8 Sinoatrial node dysfunction (Bradycardia) Circulatory System 0.942 0.847 – 1.05 0.277 372 3768 exclusion phecode
427.9 Palpitations Circulatory System 1 0.97 – 1.04 0.816 3540 36229 exclusion phecode
428 Congestive heart failure; nonhypertensive Circulatory System 1.03 1 – 1.07 0.0385 4440 51854 exclusion phecode
428.1 Congestive heart failure (CHF) NOS Circulatory System 1.02 0.972 – 1.08 0.373 1530 19540 exclusion phecode
428.2 Heart failure NOS Circulatory System 1.03 0.999 – 1.07 0.0572 3573 41209 exclusion phecode
429
Ill-defined descriptions and complications of
Ill-defined descriptions and complications of heart disease
 Circulatory System 0.994 0.917 – 1.08 0.884 644 6769 exclusion phecode
429.1 Heart transplant/surgery Circulatory System 0.956 0.72 – 1.27 0.756 50 593 exclusion phecode
429.2 Abnormal function study of cardiovascular system Circulatory System 0.98 0.892 – 1.08 0.68 467 4932 exclusion phecode
429.3 Symptoms involving cardiovascular system Circulatory System 1.04 0.895 – 1.21 0.598 178 1875 exclusion phecode
430 Intracranial hemorrhage Circulatory System 0.996 0.948 – 1.05 0.882 1728 17643 exclusion phecode
430.1 Subarachnoid hemorrhage Circulatory System 0.991 0.922 – 1.07 0.806 792 7897 exclusion phecode
430.2 Intracerebral hemorrhage Circulatory System 1.03 0.952 – 1.11 0.465 682 7126 exclusion phecode
430.3 Subdural hemorrhage Circulatory System 0.905 0.793 – 1.03 0.136 245 2472 exclusion phecode
433 Cerebrovascular disease Circulatory System 1.02 1 – 1.05 0.0536 7542 81511 exclusion phecode
433.1 Occlusion and stenosis of precerebral arteries Circulatory System 1.09 1.03 – 1.17 0.0067 1002 10895 exclusion phecode
433.12 Cerebral atherosclerosis Circulatory System 1.09 0.939 – 1.26 0.265 198 2083 exclusion phecode
433.2 Occlusion of cerebral arteries Circulatory System 1.04 1.01 – 1.08 0.0198 3595 39337 exclusion phecode
433.21
Cerebral artery occlusion, with cerebral
Cerebral artery occlusion, with cerebral infarction
 Circulatory System 1.09 1.03 – 1.15 0.00348 1398 15620 exclusion phecode
433.3 Cerebral ischemia Circulatory System 0.988 0.948 – 1.03 0.568 2491 26988 exclusion phecode
433.31 Transient cerebral ischemia Circulatory System 0.997 0.951 – 1.05 0.908 1841 19872 exclusion phecode
433.5 Cerebral aneurysm Circulatory System 0.985 0.887 – 1.09 0.779 375 3726 exclusion phecode
433.8 Late effects of cerebrovascular disease Circulatory System 1.07 1 – 1.14 0.0398 1067 11931 exclusion phecode
440 Atherosclerosis Circulatory System 1.13 1.06 – 1.2 0.000139 1071 12769 exclusion phecode
440.1 Atherosclerosis of renal artery Circulatory System 1.19 0.962 – 1.47 0.11 93 1050 exclusion phecode
440.2 Atherosclerosis of the extremities Circulatory System 1.12 1.03 – 1.21 0.0106 585 7417 exclusion phecode
440.9 Atherosclerosis of aorta Circulatory System 1.14 0.995 – 1.3 0.0596 240 2683 exclusion phecode
441 Vascular insufficiency of intestine Circulatory System 1.02 0.93 – 1.11 0.721 547 5781 exclusion phecode
441.1 Acute vascular insufficiency of intestine Circulatory System 0.986 0.866 – 1.12 0.834 251 2662 exclusion phecode
442 Other aneurysm Circulatory System 1.01 0.962 – 1.06 0.677 1708 17490 exclusion phecode
442.1 Aortic aneurysm Circulatory System 0.997 0.942 – 1.05 0.911 1319 13408 exclusion phecode
442.11 Abdominal aortic aneurysm Circulatory System 1.04 0.969 – 1.12 0.276 820 8506 exclusion phecode
442.2 Aneurysm of iliac artery Circulatory System 1.08 0.875 – 1.34 0.471 94 917 exclusion phecode
442.3 Aneurysm of artery of lower extremity Circulatory System 1.09 0.916 – 1.29 0.343 146 1570 exclusion phecode
442.4 Arterial dissection Circulatory System 0.803 0.605 – 1.07 0.131 51 514 exclusion phecode
442.8 Aneurysm of other specified artery Circulatory System 1.04 0.895 – 1.21 0.61 185 1913 exclusion phecode
443 Peripheral vascular disease Circulatory System 1.04 1 – 1.08 0.0478 3006 36571 exclusion phecode
443.1 Raynaud's syndrome Circulatory System 0.995 0.934 – 1.06 0.867 1086 10870 exclusion phecode
443.7
Peripheral angiopathy in diseases classified
Peripheral angiopathy in diseases classified elsewhere
 Circulatory System 1.02 0.763 – 1.36 0.904 41 3589 exclusion phecode
443.8 Other specified peripheral vascular diseases Circulatory System 1.04 0.999 – 1.08 0.0557 2974 34365 exclusion phecode
443.9 Peripheral vascular disease, unspecified Circulatory System 1.07 1.02 – 1.12 0.00689 1922 23831 exclusion phecode
444 Arterial embolism and thrombosis Circulatory System 1.07 0.989 – 1.15 0.0965 718 8610 exclusion phecode
444.1
Arterial embolism and thrombosis of lower
Arterial embolism and thrombosis of lower extremity artery
 Circulatory System 1.17 1.06 – 1.29 0.0019 406 5146 exclusion phecode
446 Polyarteritis nodosa and allied conditions Circulatory System 1 0.931 – 1.08 0.924 741 7678 exclusion phecode
446.4 Wegener's granulomatosis Circulatory System 1.02 0.872 – 1.18 0.833 172 1723 exclusion phecode
446.5 Giant cell arteritis Circulatory System 1.01 0.903 – 1.12 0.899 357 3634 exclusion phecode
446.9 Arteritis NOS Circulatory System 1.02 0.892 – 1.18 0.734 210 2248 exclusion phecode
447 Other disorders of arteries and arterioles Circulatory System 1.08 1.02 – 1.15 0.0117 1057 12339 exclusion phecode
447.1 Stricture of artery Circulatory System 1.16 1.08 – 1.26 0.000157 662 8034 exclusion phecode
448 Disease of capillaries Circulatory System 0.846 0.707 – 1.01 0.0673 126 1350 exclusion phecode
450 Noninfectious disorders of lymphatic channels Circulatory System 0.961 0.885 – 1.04 0.343 622 6653 exclusion phecode
451 Phlebitis and thrombophlebitis Circulatory System 1.07 1.03 – 1.11 0.000119 3583 37235 exclusion phecode
451.2
Phlebitis and thrombophlebitis of lower
Phlebitis and thrombophlebitis of lower extremities
 Circulatory System 1.08 1.04 – 1.12 5.38e-05 3333 34673 exclusion phecode
452 Other venous embolism and thrombosis Circulatory System 0.961 0.877 – 1.05 0.387 504 5325 exclusion phecode
454 Varicose veins Circulatory System 0.998 0.978 – 1.02 0.847 10645 106214 exclusion phecode
454.1 Varicose veins of lower extremity Circulatory System 0.998 0.979 – 1.02 0.855 10991 109279 exclusion phecode
454.11 Varicose veins of lower extremity, symptomtic Circulatory System 0.934 0.855 – 1.02 0.127 559 5934 exclusion phecode
455 Hemorrhoids Circulatory System 1 0.988 – 1.02 0.82 21963 221341 exclusion phecode
456 Chronic venous insufficiency [CVI] Circulatory System 0.856 0.729 – 1.01 0.0578 157 1731 exclusion phecode
457
Encounter for long-term (current) use of
Encounter for long-term (current) use of anticoagulants, antithrombotics, aspirin
 Circulatory System 1.12 0.896 – 1.39 0.323 93 886 exclusion phecode
458 Hypotension Circulatory System 0.992 0.964 – 1.02 0.582 5060 54226 exclusion phecode
458.1 Orthostatic hypotension Circulatory System 0.975 0.917 – 1.04 0.416 1127 12541 exclusion phecode
458.2 Iatrogenic hypotension Circulatory System 1.06 0.92 – 1.23 0.404 203 2184 exclusion phecode
458.9 Hypotension NOS Circulatory System 1.01 0.969 – 1.04 0.753 3061 32860 exclusion phecode
459 Other disorders of circulatory system Circulatory System 1.01 0.995 – 1.03 0.177 14299 150891 exclusion phecode
459.1 Hemorrhage NOS Circulatory System 1.08 0.9 – 1.3 0.4 127 1317 exclusion phecode
459.9 Circulatory disease NEC Circulatory System 1.01 0.995 – 1.03 0.165 14148 149588 exclusion phecode
464 Acute sinusitis Respiratory 1.06 0.902 – 1.24 0.492 179 1865 exclusion phecode
465
Acute upper respiratory infections of multiple
Acute upper respiratory infections of multiple or unspecified sites
 Respiratory 1.03 0.984 – 1.08 0.214 2081 21652 exclusion phecode
465.2 Acute pharyngitis Respiratory 1.04 0.968 – 1.12 0.271 767 7913 exclusion phecode
465.4 Acute laryngitis and tracheitis Respiratory 0.96 0.815 – 1.13 0.63 155 1573 exclusion phecode
470 Septal Deviations/Turbinate Hypertrophy Respiratory 1.01 0.982 – 1.04 0.432 4369 44045 exclusion phecode
471 Nasal polyps Respiratory 1 0.968 – 1.04 0.8 3095 30910 exclusion phecode
472 Chronic pharyngitis and nasopharyngitis Respiratory 0.981 0.915 – 1.05 0.578 904 9064 exclusion phecode
473 Diseases of the larynx and vocal cords Respiratory 1.01 0.972 – 1.06 0.521 2338 23998 exclusion phecode
473.1 Chronic laryngitis Respiratory 0.899 0.731 – 1.11 0.315 92 976 exclusion phecode
473.3 Paralysis/spasm of vocal cords or larynx Respiratory 1.07 0.936 – 1.22 0.319 239 2490 exclusion phecode
473.4 Voice disturbance Respiratory 0.981 0.919 – 1.05 0.579 975 10113 exclusion phecode
474 Acute and chronic tonsillitis Respiratory 1.02 0.97 – 1.07 0.451 1679 16979 exclusion phecode
474.1 Acute tonsillitis Respiratory 1 0.916 – 1.09 0.998 513 5287 exclusion phecode
474.2 Chronic tonsillitis and adenoiditis Respiratory 1.06 0.994 – 1.13 0.076 1070 10754 exclusion phecode
475 Chronic sinusitis Respiratory 1.02 0.979 – 1.07 0.322 2423 24482 exclusion phecode
476 Allergic rhinitis Respiratory 0.977 0.915 – 1.04 0.49 994 10060 exclusion phecode
477 Epistaxis or throat hemorrhage Respiratory 1 0.961 – 1.05 0.847 2190 22832 exclusion phecode
478 Throat pain Respiratory 1.04 0.929 – 1.16 0.523 351 3573 exclusion phecode
479 Other upper respiratory disease Respiratory 1.01 0.973 – 1.04 0.709 3780 38512 exclusion phecode
480 Pneumonia Respiratory 1.01 0.985 – 1.03 0.583 9060 96649 exclusion phecode
480.1 Bacterial pneumonia Respiratory 0.989 0.963 – 1.02 0.438 5822 62035 exclusion phecode
480.11 Pneumococcal pneumonia Respiratory 0.978 0.951 – 1.01 0.125 5175 54956 exclusion phecode
480.12 Pseudomonal pneumonia Respiratory 1.2 0.97 – 1.49 0.0929 84 854 exclusion phecode
480.2 Viral pneumonia Respiratory 1.28 0.997 – 1.63 0.0528 67 677 exclusion phecode
480.3 Pneumonia due to fungus (mycoses) Respiratory 0.948 0.767 – 1.17 0.624 91 921 exclusion phecode
480.5 Bronchopneumonia and lung abscess Respiratory 1 0.926 – 1.08 0.981 686 7400 exclusion phecode
481 Influenza Respiratory 1.01 0.899 – 1.13 0.874 310 3102 exclusion phecode
483 Acute bronchitis and bronchiolitis Respiratory 1.09 0.933 – 1.28 0.274 170 1806 exclusion phecode
495 Asthma Respiratory 1.03 1.02 – 1.04 3.27e-05 23495 237944 exclusion phecode
495.2 Asthma with exacerbation Respiratory 1.02 0.89 – 1.18 0.747 218 2384 exclusion phecode
496 Chronic airway obstruction Respiratory 1.04 1.01 – 1.06 0.00161 9132 94825 exclusion phecode
496.1 Emphysema Respiratory 1.01 0.954 – 1.06 0.847 1565 16169 exclusion phecode
496.2 Chronic bronchitis Respiratory 1.02 0.981 – 1.06 0.299 2544 27371 exclusion phecode
496.21 Obstructive chronic bronchitis Respiratory 1.02 0.981 – 1.07 0.281 2340 25095 exclusion phecode
496.3 Bronchiectasis Respiratory 1.03 0.979 – 1.08 0.26 1737 17711 exclusion phecode
497 Bronchitis Respiratory 0.979 0.898 – 1.07 0.624 566 5926 exclusion phecode
500 Lung disease due to external agents Respiratory 1.02 0.914 – 1.14 0.732 360 3774 exclusion phecode
500.1 Extrinsic allergic alveolitis Respiratory 1.2 0.945 – 1.53 0.133 72 730 exclusion phecode
500.2 Pneumoconiosis Respiratory 0.994 0.86 – 1.15 0.931 210 2186 exclusion phecode
501 Pneumonitis due to inhalation of food or vomitus Respiratory 1.01 0.93 – 1.1 0.754 570 6095 exclusion phecode
502 Postinflammatory pulmonary fibrosis Respiratory 0.982 0.913 – 1.06 0.614 803 8485 exclusion phecode
503 Pulmonary congestion and hypostasis Respiratory 0.923 0.832 – 1.02 0.132 387 4746 exclusion phecode
504 Other alveolar and parietoalveolar pneumonopathy Respiratory 1.05 0.932 – 1.19 0.415 287 3065 exclusion phecode
505 Other pulmonary inflamation or edema Respiratory 0.883 0.672 – 1.16 0.372 57 567 exclusion phecode
506 Empyema and pneumothorax Respiratory 0.983 0.923 – 1.05 0.601 1040 10616 exclusion phecode
507 Pleurisy; pleural effusion Respiratory 1.01 0.982 – 1.04 0.53 5653 60009 exclusion phecode
508
Pulmonary collapse; interstitial and
Pulmonary collapse; interstitial and compensatory emphysema
 Respiratory 0.937 0.892 – 0.984 0.00874 1778 18719 exclusion phecode
509 Respiratory failure, insufficiency, arrest Respiratory 1.02 0.974 – 1.06 0.433 2189 24263 exclusion phecode
509.1 Respiratory failure Respiratory 1.03 0.982 – 1.08 0.218 1740 19285 exclusion phecode
509.2 Respiratory insufficiency Respiratory 1.02 0.964 – 1.07 0.572 1529 16876 exclusion phecode
509.5 Respiratory arrest Respiratory 0.887 0.743 – 1.06 0.186 127 1341 exclusion phecode
509.8
Dependence on respirator [Ventilator] or
Dependence on respirator [Ventilator] or supplemental oxygen
 Respiratory 1.08 0.96 – 1.21 0.203 316 3606 exclusion phecode
510 Other diseases of lung Respiratory 1.07 0.986 – 1.15 0.11 678 7063 exclusion phecode
512 Other symptoms of respiratory system Respiratory 1.02 0.997 – 1.04 0.0851 7972 85020 exclusion phecode
512.1 Wheezing Respiratory 1.03 0.888 – 1.19 0.698 191 2053 exclusion phecode
512.2 Painful respiration Respiratory 1.11 0.957 – 1.28 0.173 199 1962 exclusion phecode
512.7 Shortness of breath Respiratory 1.03 0.997 – 1.06 0.0843 5100 55012 exclusion phecode
512.8 Cough Respiratory 0.987 0.948 – 1.03 0.526 2587 26966 exclusion phecode
512.9 Other dyspnea Respiratory 1.02 0.947 – 1.1 0.622 787 8567 exclusion phecode
513 Respiratory abnormalities Respiratory 1.04 0.952 – 1.14 0.381 522 5717 exclusion phecode
513.3 Hypoventilation Respiratory 1 0.77 – 1.3 0.988 57 776 exclusion phecode
513.4 Hyperventilation Respiratory 1.18 1.04 – 1.35 0.0105 252 2633 exclusion phecode
513.8 Disorders of diaphragm Respiratory 1.06 0.891 – 1.27 0.493 134 1427 exclusion phecode
514 Abnormal findings examination of lungs Respiratory 1.01 0.971 – 1.06 0.529 2225 22934 exclusion phecode
516 Abnormal sputum Respiratory 1.01 0.962 – 1.06 0.735 1893 19892 exclusion phecode
516.1 Hemoptysis Respiratory 1.01 0.962 – 1.06 0.701 1838 19364 exclusion phecode
519
Other diseases of respiratory system, not
Other diseases of respiratory system, not elsewhere classified
 Respiratory 1.01 0.988 – 1.03 0.353 8205 87976 exclusion phecode
519.2 Respiratory complications Respiratory 0.92 0.815 – 1.04 0.175 287 3066 exclusion phecode
519.8 Other diseases of respiratory system, NEC Respiratory 1.01 0.99 – 1.04 0.261 7743 83171 exclusion phecode
519.9
Symptoms involving respiratory system and other
Symptoms involving respiratory system and other chest symptoms
 Respiratory 1 0.888 – 1.13 0.973 285 2872 exclusion phecode
520 Disorders of tooth development Digestive 0.988 0.943 – 1.04 0.605 1937 19484 exclusion phecode
520.1 Hereditary disturbances in tooth structure Digestive 1.09 0.81 – 1.46 0.579 50 512 exclusion phecode
520.2 Disturbances in tooth eruption Digestive 1 0.96 – 1.05 0.91 2249 22566 exclusion phecode
521 Diseases of hard tissues of teeth Digestive 1.03 0.992 – 1.07 0.12 2715 28722 exclusion phecode
521.1 Dental caries Digestive 1.04 0.999 – 1.08 0.0567 2724 28828 exclusion phecode
522 Diseases of pulp and periapical tissues Digestive 1.01 0.957 – 1.06 0.804 1665 16910 exclusion phecode
522.5 Periapical abscess Digestive 0.994 0.934 – 1.06 0.843 1089 11171 exclusion phecode
523 Gingival and periodontal diseases Digestive 0.994 0.943 – 1.05 0.809 1574 16027 exclusion phecode
523.1 Gingivitis Digestive 1.1 0.903 – 1.34 0.34 109 1073 exclusion phecode
523.3 Periodontitis (acute or chronic) Digestive 0.979 0.92 – 1.04 0.501 1110 11138 exclusion phecode
523.31 Acute periodontitis Digestive 0.999 0.921 – 1.08 0.988 636 6402 exclusion phecode
523.32 Chronic periodontitis Digestive 0.949 0.869 – 1.04 0.243 534 5310 exclusion phecode
524 Dentofacial anomalies, including malocclusion Digestive 1.1 0.984 – 1.24 0.0935 319 3167 exclusion phecode
524.3 Anomalies of tooth position/malocclusion Digestive 1.1 0.974 – 1.24 0.124 294 2909 exclusion phecode
525
Other diseases of the teeth and supporting
Other diseases of the teeth and supporting structures
 Digestive 1.01 0.971 – 1.06 0.557 2453 25252 exclusion phecode
525.2 Atrophy of edentulous alveolar ridge Digestive 0.86 0.673 – 1.1 0.227 68 675 exclusion phecode
526 Diseases of the jaws Digestive 0.995 0.929 – 1.07 0.893 877 8840 exclusion phecode
526.1 Cysts of the jaws Digestive 0.96 0.855 – 1.08 0.496 306 3125 exclusion phecode
526.3 Anomalies of jaw size/symmetry Digestive 0.898 0.691 – 1.17 0.423 59 588 exclusion phecode
526.4 Temporomandibular joint disorders Digestive 1.02 0.893 – 1.16 0.79 232 2317 exclusion phecode
526.41 Temporomandibular joint disorder, unspecified Digestive 1.01 0.889 – 1.16 0.833 225 2252 exclusion phecode
526.5 Inflammatory conditions of jaw Digestive 1.03 0.837 – 1.27 0.781 101 1048 exclusion phecode
526.9 Jaw disease NOS Digestive 1.01 0.875 – 1.16 0.936 221 2187 exclusion phecode
527 Diseases of the salivary glands Digestive 1.08 0.998 – 1.18 0.056 631 6570 exclusion phecode
527.1 Hypertrophy of salivary gland Digestive 1.04 0.833 – 1.3 0.722 77 790 exclusion phecode
527.2 Sialoadenitis Digestive 1.04 0.93 – 1.17 0.478 331 3475 exclusion phecode
527.7 Disturbance of salivary secretion Digestive 1.01 0.781 – 1.31 0.921 58 585 exclusion phecode
527.8 Other specified diseases of the salivary glands Digestive 1.09 0.897 – 1.33 0.387 114 1130 exclusion phecode
528
Diseases of the oral soft tissues, excluding
Diseases of the oral soft tissues, excluding lesions specific for gingiva and tongue
 Digestive 1.02 0.989 – 1.06 0.188 3592 36647 exclusion phecode
528.1 Stomatitis and mucositis Digestive 0.989 0.895 – 1.09 0.828 426 4417 exclusion phecode
528.11 Stomatitis and mucositis (ulcerative) Digestive 0.985 0.883 – 1.1 0.791 354 3675 exclusion phecode
528.12 Oral aphthae Digestive 1.04 0.831 – 1.3 0.737 76 795 exclusion phecode
528.3 Cellulitis and abscess of oral soft tissues Digestive 1.04 0.887 – 1.22 0.623 161 1693 exclusion phecode
528.4 Cysts of oral soft tissues Digestive 0.969 0.799 – 1.18 0.752 119 1152 exclusion phecode
528.41 Cyst of the salivary gland Digestive 0.983 0.794 – 1.22 0.872 92 889 exclusion phecode
528.5 Diseases of lips Digestive 0.988 0.912 – 1.07 0.767 648 6442 exclusion phecode
528.6 Leukoplakia of oral mucosa Digestive 1.19 1.06 – 1.35 0.00439 282 2915 exclusion phecode
528.7 Sialolithiasis Digestive 1.04 0.921 – 1.17 0.537 288 2949 exclusion phecode
529 Diseases and other conditions of the tongue Digestive 0.975 0.918 – 1.04 0.423 1127 11615 exclusion phecode
529.1 Glossitis Digestive 1.04 0.919 – 1.18 0.52 269 2816 exclusion phecode
530 Diseases of esophagus Digestive 1.02 1.01 – 1.03 0.00206 30729 264360 exclusion phecode
530.1 Esophagitis, GERD and related diseases Digestive 1.02 1.01 – 1.03 0.000654 28746 257848 exclusion phecode
530.11 GERD Digestive 1.02 1.01 – 1.03 0.00746 20933 213547 exclusion phecode
530.12 Ulcer of esophagus Digestive 1.03 0.997 – 1.06 0.0833 4732 48651 exclusion phecode
530.14 Reflux esophagitis Digestive 1.02 0.999 – 1.04 0.0618 9652 98531 exclusion phecode
530.2 Esophageal bleeding (varices/hemorrhage) Digestive 1.02 0.965 – 1.07 0.505 1449 15782 exclusion phecode
530.3 Stricture and stenosis of esophagus Digestive 1 0.951 – 1.05 0.994 1716 17450 exclusion phecode
530.5 Disorders of esophageal motility Digestive 0.966 0.889 – 1.05 0.416 591 6027 exclusion phecode
530.6 Diverticulum of esophagus, acquired Digestive 0.926 0.78 – 1.1 0.38 141 1432 exclusion phecode
530.7 Gastroesophageal laceration-hemorrhage syndrome Digestive 0.958 0.851 – 1.08 0.476 307 3240 exclusion phecode
530.9 Heartburn Digestive 1.01 0.965 – 1.06 0.635 1963 19749 exclusion phecode
531 Peptic ulcer (excl. esophageal) Digestive 1.02 0.998 – 1.05 0.0666 6334 66470 exclusion phecode
531.1 Hemorrhage from gastrointestinal ulcer Digestive 1.01 0.926 – 1.1 0.837 576 5886 exclusion phecode
531.2 Gastric ulcer Digestive 1 0.968 – 1.04 0.95 3616 38404 exclusion phecode
531.3 Duodenal ulcer Digestive 1.07 1.03 – 1.11 0.000683 2710 27967 exclusion phecode
531.4 Peptic ulcer, site unspecified Digestive 1.05 0.947 – 1.17 0.345 378 3960 exclusion phecode
532 Dysphagia Digestive 0.994 0.967 – 1.02 0.637 5929 60706 exclusion phecode
535 Gastritis and duodenitis Digestive 1.02 1.01 – 1.03 0.00143 25512 247401 exclusion phecode
535.1 Acute gastritis Digestive 1.17 1.1 – 1.25 9.36e-07 1043 11095 exclusion phecode
535.2 Atrophic gastritis Digestive 1.01 0.9 – 1.13 0.905 332 3460 exclusion phecode
535.6 Duodenitis Digestive 1.03 1 – 1.05 0.0466 6866 71419 exclusion phecode
535.8 Other specified gastritis Digestive 1.04 1.02 – 1.07 0.00141 7303 76187 exclusion phecode
535.9 Gastritis and duodenitis, NOS Digestive 1.13 0.935 – 1.38 0.202 111 1112 exclusion phecode
536.8
Dyspepsia and other specified disorders of
Dyspepsia and other specified disorders of function of stomach
 Digestive 1.04 0.912 – 1.19 0.557 237 2437 exclusion phecode
537 Other disorders of stomach and duodenum Digestive 1.02 0.981 – 1.06 0.351 3017 31937 exclusion phecode
540 Appendiceal conditions Digestive 1.01 0.977 – 1.05 0.449 2946 29333 exclusion phecode
540.1 Appendicitis Digestive 1.02 0.977 – 1.06 0.435 2768 27499 exclusion phecode
540.11 Acute appendicitis Digestive 1.01 0.97 – 1.05 0.598 2486 24685 exclusion phecode
550 Abdominal hernia Digestive 1.01 0.999 – 1.02 0.0667 42036 267890 exclusion phecode
550.1 Inguinal hernia Digestive 0.995 0.978 – 1.01 0.55 15043 114143 exclusion phecode
550.2 Diaphragmatic hernia Digestive 1.02 1 – 1.03 0.00876 24303 225693 exclusion phecode
550.3 Femoral hernia Digestive 0.934 0.86 – 1.01 0.106 643 6178 exclusion phecode
550.4 Umbilical hernia Digestive 1.01 0.971 – 1.04 0.715 3231 34608 exclusion phecode
550.5 Ventral hernia Digestive 0.986 0.95 – 1.02 0.446 3094 32276 exclusion phecode
555
Inflammatory bowel disease and other
Inflammatory bowel disease and other gastroenteritis and colitis
 Digestive 0.998 0.966 – 1.03 0.893 4110 42198 exclusion phecode
555.1 Regional enteritis Digestive 1.05 0.994 – 1.1 0.0819 1615 16508 exclusion phecode
555.2 Ulcerative colitis Digestive 0.985 0.948 – 1.02 0.427 2925 30119 exclusion phecode
555.21 Ulcerative colitis (chronic) Digestive 0.932 0.849 – 1.02 0.132 500 5102 exclusion phecode
556 Ulceration of the lower GI tract Digestive 1.01 0.943 – 1.07 0.837 980 10066 exclusion phecode
556.1 Ulceration of intestine Digestive 1.04 0.958 – 1.13 0.362 624 6385 exclusion phecode
557 Intestinal malabsorption (non-celiac) Digestive 1.08 0.956 – 1.23 0.207 269 2867 exclusion phecode
557.1 Celiac disease Digestive 1.08 1.03 – 1.14 0.00189 1728 17479 exclusion phecode
558 Noninfectious gastroenteritis Digestive 1.02 0.998 – 1.03 0.0772 13933 147608 exclusion phecode
559 Ileostomy status Digestive 0.954 0.905 – 1.01 0.0804 1505 15646 exclusion phecode
560 Intestinal obstruction without mention of hernia Digestive 1 0.97 – 1.04 0.837 3625 37175 exclusion phecode
560.1 Paralytic ileus Digestive 0.985 0.896 – 1.08 0.744 475 4886 exclusion phecode
560.2 Impaction of intestine Digestive 0.997 0.875 – 1.14 0.969 245 2535 exclusion phecode
560.3 Peritoneal or intestinal adhesions Digestive 1 0.929 – 1.08 0.982 773 7898 exclusion phecode
560.4 Other intestinal obstruction Digestive 1 0.964 – 1.04 0.968 3106 31745 exclusion phecode
561 Symptoms involving digestive system Digestive 1.01 0.995 – 1.03 0.153 14628 150168 exclusion phecode
561.1 Diarrhea Digestive 1.01 0.917 – 1.11 0.839 442 4407 exclusion phecode
561.2 Flatulence Digestive 1 0.953 – 1.06 0.907 1577 16031 exclusion phecode
562 Diverticulosis and diverticulitis Digestive 1.01 0.994 – 1.02 0.277 24336 200327 exclusion phecode
562.1 Diverticulosis Digestive 1.01 0.994 – 1.02 0.302 24304 200278 exclusion phecode
563 Constipation Digestive 1.01 0.991 – 1.03 0.253 9388 97782 exclusion phecode
564 Functional digestive disorders Digestive 1.02 1.01 – 1.04 0.00124 19892 199204 exclusion phecode
564.1 Irritable Bowel Syndrome Digestive 1.03 1.01 – 1.07 0.0199 5125 52788 exclusion phecode
564.8
Abnormal findings on exam of gastrointestinal
Abnormal findings on exam of gastrointestinal tract/ abdominal area
 Digestive 0.987 0.936 – 1.04 0.624 1506 15594 exclusion phecode
564.9 Personal history of diseases of digestive system Digestive 1.03 1.01 – 1.05 0.00232 13876 143160 exclusion phecode
565 Anal and rectal conditions Digestive 1.02 1.01 – 1.04 0.00736 13575 138890 exclusion phecode
565.1 Anal and rectal polyp Digestive 1.01 0.988 – 1.04 0.302 6731 68946 exclusion phecode
567 Peritonitis and retroperitoneal infections Digestive 0.977 0.909 – 1.05 0.532 807 8736 exclusion phecode
568 Other disorders of peritoneum Digestive 1.04 0.999 – 1.08 0.0539 3010 30910 exclusion phecode
568.1
Peritoneal adhesions (postoperative)
Peritoneal adhesions (postoperative) (postinfection)
 Digestive 1.04 1 – 1.08 0.0338 2863 29370 exclusion phecode
569 Other disorders of intestine Digestive 1.02 0.988 – 1.06 0.22 3781 39469 exclusion phecode
569.1 Toxic gastroenteritis and colitis Digestive 0.959 0.803 – 1.14 0.639 130 1387 exclusion phecode
569.2 Gastrointestinal complications Digestive 1.02 0.923 – 1.12 0.732 452 4552 exclusion phecode
571 Chronic liver disease and cirrhosis Digestive 1.04 0.996 – 1.08 0.0754 2298 27875 exclusion phecode
571.5 Other chronic nonalcoholic liver disease Digestive 1.08 1.02 – 1.14 0.0115 1276 15957 exclusion phecode
571.51 Cirrhosis of liver without mention of alcohol Digestive 1.18 0.951 – 1.45 0.133 85 1064 exclusion phecode
571.6 Primary biliary cirrhosis Digestive 1.08 0.943 – 1.24 0.266 235 2450 exclusion phecode
571.8
Liver abscess and sequelae of chronic liver
Liver abscess and sequelae of chronic liver disease
 Digestive 0.979 0.908 – 1.05 0.572 752 9194 exclusion phecode
571.81 Portal hypertension Digestive 1.02 0.916 – 1.13 0.76 380 4962 exclusion phecode
572 Ascites (non malignant) Digestive 1.08 1.02 – 1.14 0.00992 1327 14521 exclusion phecode
573 Other disorders of liver Digestive 0.97 0.917 – 1.03 0.293 1341 14109 exclusion phecode
573.2 Liver replaced by transplant Digestive 1.18 0.931 – 1.49 0.172 72 901 exclusion phecode
573.3 Hepatomegaly Digestive 1.03 0.899 – 1.17 0.709 244 2785 exclusion phecode
573.5 Jaundice (not of newborn) Digestive 0.993 0.923 – 1.07 0.851 798 8392 exclusion phecode
573.7 Abnormal results of function study of liver Digestive 1.05 1.01 – 1.09 0.012 3027 32618 exclusion phecode
573.9 Abnormal serum enzyme levels Digestive 0.866 0.742 – 1.01 0.0671 182 1938 exclusion phecode
574 Cholelithiasis and cholecystitis Digestive 1.06 1.04 – 1.07 3.72e-10 14237 148220 exclusion phecode
574.1 Cholelithiasis Digestive 1.05 1.04 – 1.07 1.97e-08 12362 128746 exclusion phecode
574.11 Cholelithiasis with acute cholecystitis Digestive 1.03 0.976 – 1.09 0.269 1362 14233 exclusion phecode
574.12 Cholelithiasis with other cholecystitis Digestive 1.05 1.02 – 1.08 0.00139 4994 51608 exclusion phecode
574.2 Calculus of bile duct Digestive 1.03 0.988 – 1.08 0.156 2397 24744 exclusion phecode
574.3 Cholecystitis without cholelithiasis Digestive 1.06 1.02 – 1.1 0.00611 2453 26038 exclusion phecode
575 Other biliary tract disease Digestive 1.04 1 – 1.07 0.0455 3517 36487 exclusion phecode
575.1 Cholangitis Digestive 1.05 0.95 – 1.15 0.354 439 4584 exclusion phecode
575.2 Obstruction of bile duct Digestive 0.993 0.919 – 1.07 0.854 687 7223 exclusion phecode
575.6 Cholesterolosis of gallbladder Digestive 1.23 1.12 – 1.36 3.56e-05 429 4368 exclusion phecode
575.7 Other disorders of gallbladder Digestive 1.07 1.01 – 1.13 0.0203 1296 13362 exclusion phecode
575.8 Other disorders of biliary tract Digestive 0.969 0.906 – 1.04 0.362 937 9770 exclusion phecode
575.9
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of biliary tract
 Digestive 0.932 0.83 – 1.05 0.234 311 3264 exclusion phecode
577 Diseases of pancreas Digestive 1.03 0.983 – 1.07 0.245 2318 25039 exclusion phecode
577.1 Acute pancreatitis Digestive 1.04 0.991 – 1.09 0.109 1749 18760 exclusion phecode
577.2 Chronic pancreatitis Digestive 0.967 0.873 – 1.07 0.526 402 4821 exclusion phecode
577.3 Cyst and pseudocyst of pancreas Digestive 0.949 0.844 – 1.07 0.388 306 3419 exclusion phecode
578 Gastrointestinal hemorrhage Digestive 0.998 0.984 – 1.01 0.843 19004 194935 exclusion phecode
578.1 Hematemesis Digestive 1.02 0.975 – 1.08 0.333 1710 18403 exclusion phecode
578.2 Blood in stool Digestive 1.02 0.977 – 1.06 0.368 2348 24635 exclusion phecode
578.8 Hemorrhage of rectum and anus Digestive 0.997 0.978 – 1.02 0.722 12141 123882 exclusion phecode
578.9 Hemorrhage of gastrointestinal tract Digestive 0.992 0.963 – 1.02 0.575 4852 49810 exclusion phecode
579 Other symptoms involving abdomen and pelvis Digestive 1 0.951 – 1.06 0.861 1360 14667 exclusion phecode
579.2 Splenomegaly Digestive 0.998 0.891 – 1.12 0.975 332 3963 exclusion phecode
579.8 Nonspecific abnormal findings in stool contents Digestive 0.992 0.941 – 1.05 0.781 1505 15642 exclusion phecode
580 Nephritis; nephrosis; renal sclerosis Genitourinary 1.02 0.956 – 1.08 0.588 1062 14380 exclusion phecode
580.1 Glomerulonephritis Genitourinary 1.04 0.963 – 1.11 0.344 790 9865 exclusion phecode
580.11 Proliferative glomerulonephritis Genitourinary 1.07 0.843 – 1.37 0.561 65 695 exclusion phecode
580.12 Non-proliferative glomerulonephritis Genitourinary 1.05 0.875 – 1.27 0.586 120 1288 exclusion phecode
580.14 Chronic glomerulonephritis, NOS Genitourinary 1 0.925 – 1.09 0.932 634 8183 exclusion phecode
580.2
Nephrotic syndrome without mention of
Nephrotic syndrome without mention of glomerulonephritis
 Genitourinary 0.974 0.852 – 1.11 0.693 227 4397 exclusion phecode
580.3
Nephritis and nephropathy without mention of
Nephritis and nephropathy without mention of glomerulonephritis
 Genitourinary 1.05 0.906 – 1.21 0.542 204 2328 exclusion phecode
580.32
Nephritis and nephropathy with pathological
Nephritis and nephropathy with pathological lesion
 Genitourinary 1.02 0.889 – 1.18 0.743 207 2397 exclusion phecode
585 Renal failure Genitourinary 1.01 0.982 – 1.04 0.506 5425 64995 exclusion phecode
585.1 Acute renal failure Genitourinary 1.02 0.984 – 1.05 0.301 3464 42142 exclusion phecode
585.2 Renal failure NOS Genitourinary 0.986 0.928 – 1.05 0.639 1172 13634 exclusion phecode
585.3 Chronic renal failure [CKD] Genitourinary 1.02 0.974 – 1.07 0.383 1923 24661 exclusion phecode
585.31 Renal dialysis Genitourinary 0.924 0.832 – 1.03 0.136 380 4640 exclusion phecode
586 Other disorders of the kidney and ureters Genitourinary 1.03 0.989 – 1.07 0.167 2972 31547 exclusion phecode
586.1 Anatomical abnormatilies of kidney and ureters Genitourinary 1.04 0.896 – 1.21 0.596 185 1974 exclusion phecode
586.11 Small kidney Genitourinary 1.04 0.883 – 1.23 0.635 157 1701 exclusion phecode
586.2 Cyst of kidney, acquired Genitourinary 1.03 0.972 – 1.1 0.301 1135 11756 exclusion phecode
586.3 Vascular disorders of kidney/hypertrophy Genitourinary 1.15 0.903 – 1.47 0.254 70 747 exclusion phecode
586.4 Stricture/obstruction of ureter Genitourinary 0.983 0.915 – 1.06 0.645 818 8584 exclusion phecode
587 Kidney replaced by transpant Genitourinary 0.948 0.843 – 1.07 0.372 307 3498 exclusion phecode
588 Disorders resulting from impaired renal function Genitourinary 0.882 0.702 – 1.11 0.28 78 923 exclusion phecode
589 Abnormal results of function study of kidney Genitourinary 0.89 0.721 – 1.1 0.28 94 1096 exclusion phecode
590 Pyelonephritis Genitourinary 1.04 0.984 – 1.11 0.152 1180 12664 exclusion phecode
591 Urinary tract infection Genitourinary 0.991 0.972 – 1.01 0.385 10956 116943 exclusion phecode
592 Cystitis and urethritis Genitourinary 1.02 0.985 – 1.07 0.235 2703 28064 exclusion phecode
592.1 Cystitis Genitourinary 1.02 0.977 – 1.06 0.4 2647 27483 exclusion phecode
592.11 Acute cystitis Genitourinary 1.02 0.856 – 1.22 0.827 127 1288 exclusion phecode
592.12 Chronic cystitis Genitourinary 1.02 0.952 – 1.1 0.542 809 8385 exclusion phecode
592.13 Chronic interstitial cystitis Genitourinary 1.05 0.916 – 1.2 0.491 234 2359 exclusion phecode
592.2 Urethritis and urethral syndrome Genitourinary 1.21 1.02 – 1.42 0.0255 152 1577 exclusion phecode
593 Hematuria Genitourinary 1.02 1 – 1.03 0.055 14660 150490 exclusion phecode
594 Urinary calculus Genitourinary 1.05 1.02 – 1.08 0.000995 5637 59787 exclusion phecode
594.1 Calculus of kidney Genitourinary 1.04 0.998 – 1.08 0.0637 2770 29764 exclusion phecode
594.2 Calculus of lower urinary tract Genitourinary 0.991 0.914 – 1.07 0.824 676 7198 exclusion phecode
594.3 Calculus of ureter Genitourinary 1.04 0.995 – 1.09 0.0811 2104 22472 exclusion phecode
594.8 Renal colic Genitourinary 1.09 1.04 – 1.14 0.000347 1830 19298 exclusion phecode
595 Hydronephrosis Genitourinary 1.02 0.972 – 1.07 0.398 1708 18144 exclusion phecode
596 Other disorders of bladder Genitourinary 1 0.982 – 1.03 0.704 8894 91056 exclusion phecode
596.1 Bladder neck obstruction Genitourinary 1.03 0.977 – 1.08 0.305 1785 18071 exclusion phecode
596.5 Functional disorders of bladder Genitourinary 0.977 0.926 – 1.03 0.388 1505 15631 exclusion phecode
597 Other disorders of urethra and urinary tract Genitourinary 1.01 0.974 – 1.04 0.636 3558 36701 exclusion phecode
597.1 Urethral stricture (not specified as infectious) Genitourinary 1.01 0.969 – 1.04 0.75 3002 31026 exclusion phecode
597.2 Urinary complications NEC Genitourinary 1.03 0.802 – 1.33 0.811 67 728 exclusion phecode
598 Abnormal findings on examination of urine Genitourinary 0.988 0.953 – 1.02 0.511 3201 32890 exclusion phecode
598.9
Other nonspecific findings on examination of
Other nonspecific findings on examination of urine
 Genitourinary 0.909 0.803 – 1.03 0.136 270 2848 exclusion phecode
599 Other symptoms/disorders or the urinary system Genitourinary 1.02 1.01 – 1.04 0.00434 16879 174093 exclusion phecode
599.1 Urinary obstruction Genitourinary 0.974 0.821 – 1.15 0.759 141 1543 exclusion phecode
599.2 Retention of urine Genitourinary 0.998 0.972 – 1.03 0.897 6033 62088 exclusion phecode
599.3 Dysuria Genitourinary 0.981 0.922 – 1.04 0.553 1082 11281 exclusion phecode
599.4 Urinary incontinence Genitourinary 1.04 1.02 – 1.06 0.000625 8118 83676 exclusion phecode
599.5 Frequency of urination and polyuria Genitourinary 1.02 0.982 – 1.05 0.371 3641 37653 exclusion phecode
599.6 Oliguria and anuria Genitourinary 1.05 0.837 – 1.31 0.685 84 989 exclusion phecode
599.8 Other symptoms involving urinary system Genitourinary 1.01 0.776 – 1.3 0.962 60 577 exclusion phecode
599.9 Other abnormality of urination Genitourinary 0.994 0.946 – 1.04 0.824 1726 17873 exclusion phecode
600 Hyperplasia of prostate Genitourinary 0.998 0.977 – 1.02 0.822 9996 80373 exclusion phecode
601 Inflammatory diseases of prostate Genitourinary 1.04 0.994 – 1.09 0.0872 1876 19115 exclusion phecode
601.1 Prostatitis Genitourinary 1.05 0.991 – 1.1 0.105 1456 14346 exclusion phecode
601.11 Acute prostatitis Genitourinary 0.986 0.856 – 1.14 0.84 214 2159 exclusion phecode
601.12 Chronic prostatitis Genitourinary 1.01 0.942 – 1.09 0.754 838 8250 exclusion phecode
601.3 Orchitis and epididymitis Genitourinary 0.859 0.659 – 1.12 0.262 55 543 exclusion phecode
601.4 Balanoposthitis Genitourinary 1.01 0.88 – 1.15 0.936 227 2628 exclusion phecode
601.8
Other inflammatory disorders of male genital
Other inflammatory disorders of male genital organs
 Genitourinary 1.08 0.952 – 1.22 0.232 259 2786 exclusion phecode
602 Other disorders of prostate Genitourinary 1.07 1 – 1.13 0.0365 1216 12179 exclusion phecode
603 Other disorders of testis Genitourinary 1.05 0.999 – 1.1 0.0573 1921 19960 exclusion phecode
603.1 Hydrocele Genitourinary 1.04 0.978 – 1.1 0.221 1197 12347 exclusion phecode
604 Disorders of penis Genitourinary 1.05 1.01 – 1.09 0.017 2786 30489 exclusion phecode
604.1 Redundant prepuce and phimosis/BXO Genitourinary 1.04 0.996 – 1.08 0.0792 2287 25254 exclusion phecode
605 Erectile dysfunction [ED] Genitourinary 0.983 0.858 – 1.13 0.805 222 2516 exclusion phecode
608 Other disorders of male genital organs Genitourinary 0.982 0.943 – 1.02 0.372 2616 26196 exclusion phecode
609 Male infertility and abnormal spermatozoa Genitourinary 0.988 0.85 – 1.15 0.876 190 1955 exclusion phecode
609.1 Infertility, male Genitourinary 0.913 0.7 – 1.19 0.503 57 604 exclusion phecode
609.2 Abnormal spermatozoa Genitourinary 1.04 0.871 – 1.23 0.684 149 1527 exclusion phecode
610 Benign mammary dysplasias Genitourinary 0.972 0.932 – 1.01 0.196 2382 23939 exclusion phecode
610.1 Cystic mastopathy Genitourinary 0.936 0.873 – 1 0.0582 886 8911 exclusion phecode
610.2 Fibroadenosis of breast Genitourinary 1.04 0.926 – 1.17 0.495 293 2939 exclusion phecode
610.3 Fibrosclerosis of breast Genitourinary 1.05 0.931 – 1.19 0.411 292 2908 exclusion phecode
610.4 Benign neoplasm of breast Genitourinary 0.974 0.92 – 1.03 0.367 1341 13391 exclusion phecode
610.8 Other specified benign mammary dysplasias Genitourinary 1.01 0.934 – 1.1 0.774 648 6695 exclusion phecode
611 Abnormal findings on mammogram or breast exam Genitourinary 0.968 0.918 – 1.02 0.228 1509 15151 exclusion phecode
611.1 Abnormal mammogram Genitourinary 1.05 0.803 – 1.37 0.729 56 543 exclusion phecode
611.3 Lump or mass in breast Genitourinary 0.967 0.917 – 1.02 0.227 1458 14671 exclusion phecode
612
Breast conditions, congenital or relating to
Breast conditions, congenital or relating to hormones
 Genitourinary 1.09 1.02 – 1.17 0.0159 834 8530 exclusion phecode
612.2 Hypertrophy of breast (Gynecomastia) Genitourinary 1.07 0.995 – 1.15 0.0696 792 8135 exclusion phecode
612.3 Congenital anomalies of breast Genitourinary 1.19 0.949 – 1.48 0.133 72 702 exclusion phecode
613 Other nonmalignant breast conditions Genitourinary 1.03 0.977 – 1.08 0.283 1562 15868 exclusion phecode
613.1 Inflammatory disease of breast Genitourinary 1.05 0.973 – 1.14 0.202 681 6902 exclusion phecode
613.5 Mastodynia Genitourinary 0.972 0.766 – 1.23 0.813 71 740 exclusion phecode
613.7 Other signs and symptoms in breast Genitourinary 1.04 0.963 – 1.13 0.3 674 6734 exclusion phecode
613.8 Other specified disorders of breast Genitourinary 0.983 0.876 – 1.1 0.766 308 3153 exclusion phecode
613.9 Breast disorder NOS Genitourinary 0.964 0.836 – 1.11 0.612 195 1993 exclusion phecode
614 Inflammatory diseases of female pelvic organs Genitourinary 1.04 1.01 – 1.07 0.0102 5440 55217 exclusion phecode
614.1
Pelvic peritoneal adhesions, female
Pelvic peritoneal adhesions, female (postoperative) (postinfection)
 Genitourinary 1.03 0.99 – 1.08 0.142 2415 24562 exclusion phecode
614.3 Pelvic inflammatory disease (PID) Genitourinary 1.07 0.992 – 1.15 0.0805 786 8054 exclusion phecode
614.31 Acute inflammatory pelvic disease Genitourinary 1.1 0.842 – 1.44 0.48 58 589 exclusion phecode
614.32 Chronic inflammatory pelvic disease Genitourinary 1.08 0.972 – 1.19 0.156 401 4085 exclusion phecode
614.33 Pelvic inflammatory disease, NOS Genitourinary 1.06 0.945 – 1.18 0.334 331 3406 exclusion phecode
614.4 Inflammatory diseases of uterus, except cervix Genitourinary 1.13 0.995 – 1.28 0.0606 260 2681 exclusion phecode
614.5
Inflammatory disease of cervix, vagina, and
Inflammatory disease of cervix, vagina, and vulva
 Genitourinary 1.04 0.995 – 1.08 0.0811 2489 25106 exclusion phecode
614.51 Cervicitis and endocervicitis Genitourinary 1.02 0.961 – 1.08 0.557 1273 12705 exclusion phecode
614.52 Vaginitis and vulvovaginitis Genitourinary 0.983 0.886 – 1.09 0.749 400 4104 exclusion phecode
614.53 Cyst or abscess of Bartholin's gland Genitourinary 1.04 0.963 – 1.12 0.332 738 7335 exclusion phecode
614.54 Abscess or ulceration of vulva Genitourinary 1.05 0.919 – 1.2 0.465 239 2637 exclusion phecode
615 Endometriosis Genitourinary 1.04 1 – 1.07 0.0286 3889 39090 exclusion phecode
617
Disorders secondary to childbirth, surgery
Disorders secondary to childbirth, surgery, trauma
 Genitourinary 1.11 0.98 – 1.25 0.102 282 2913 exclusion phecode
618 Genital prolapse Genitourinary 1.02 1 – 1.04 0.0347 11118 112036 exclusion phecode
618.1 Prolapse of vaginal walls Genitourinary 1.02 0.994 – 1.04 0.15 7003 70837 exclusion phecode
618.2 Uterine/Uterovaginal prolapse Genitourinary 1.03 1 – 1.06 0.0538 5155 51655 exclusion phecode
618.5 Prolapse of vaginal vault after hysterectomy Genitourinary 1.04 0.942 – 1.14 0.467 486 4904 exclusion phecode
618.6 Vaginal enterocele, congenital or acquired Genitourinary 0.993 0.915 – 1.08 0.865 644 6499 exclusion phecode
619 Noninflammatory female genital disorders Genitourinary 1.02 1 – 1.05 0.0422 8363 84184 exclusion phecode
619.1
Noninflammatory disorders of ovary, fallopian
Noninflammatory disorders of ovary, fallopian tube, and broad ligament
 Genitourinary 0.995 0.919 – 1.08 0.893 693 7033 exclusion phecode
619.2 Disorders of uterus, NEC Genitourinary 1.02 0.985 – 1.06 0.244 3193 32009 exclusion phecode
619.3 Noninflammatory disorders of cervix Genitourinary 1.05 1.01 – 1.09 0.0143 2749 27642 exclusion phecode
619.4 Noninflammatory disorders of vagina Genitourinary 0.967 0.92 – 1.02 0.192 1677 17029 exclusion phecode
619.5 Noninflammatory disorders of vulva and perineum Genitourinary 1.01 0.957 – 1.07 0.649 1300 13027 exclusion phecode
620 Dysplasia of female genital organs Genitourinary 0.926 0.731 – 1.17 0.524 69 696 exclusion phecode
621 Endometrial hyperplasia Genitourinary 1.07 1.01 – 1.14 0.0331 1039 10848 exclusion phecode
622 Polyp of female genital organs Genitourinary 1.02 0.996 – 1.04 0.106 9968 100916 exclusion phecode
622.1 Polyp of corpus uteri Genitourinary 1.02 0.999 – 1.05 0.0594 7440 75629 exclusion phecode
622.2 Mucous polyp of cervix Genitourinary 1.02 0.981 – 1.05 0.349 3310 33101 exclusion phecode
623 Hypertrophy of female genital organs Genitourinary 1.02 0.963 – 1.08 0.47 1206 12258 exclusion phecode
624 Symptoms involving female genital tract Genitourinary 1.05 0.975 – 1.13 0.202 763 7635 exclusion phecode
624.1 Dystrophy of female genital tract Genitourinary 0.98 0.856 – 1.12 0.771 223 2263 exclusion phecode
624.2 Atrophy of female genital tract Genitourinary 1.08 0.98 – 1.2 0.116 424 4232 exclusion phecode
624.9 stress incontinence, female Genitourinary 1.07 1.04 – 1.1 6.21e-06 5523 56453 exclusion phecode
625
Pain and other symptoms associated with female
Pain and other symptoms associated with female genital organs
 Genitourinary 1.02 0.98 – 1.06 0.344 2785 27865 exclusion phecode
625.1 Dyspareunia Genitourinary 1.02 0.955 – 1.08 0.63 1145 11517 exclusion phecode
626
Disorders of menstruation and other abnormal
Disorders of menstruation and other abnormal bleeding from female genital tract
 Genitourinary 1.03 1.02 – 1.05 7.49e-05 15528 111487 exclusion phecode
626.1 Irregular menstrual cycle/bleeding Genitourinary 1.04 1.02 – 1.06 2e-05 13545 106593 exclusion phecode
626.11 Absent or infrequent menstruation Genitourinary 1.01 0.821 – 1.23 0.952 104 1065 exclusion phecode
626.12 Excessive or frequent menstruation Genitourinary 1.05 1.03 – 1.07 5.71e-06 9300 88996 exclusion phecode
626.13 Irregular menstrual cycle Genitourinary 1.02 0.972 – 1.07 0.442 1893 19168 exclusion phecode
626.14 Irregular menstrual bleeding Genitourinary 1.03 1 – 1.07 0.0474 3672 36941 exclusion phecode
626.2 Dysmenorrhea Genitourinary 1.07 1.02 – 1.12 0.00976 1699 17257 exclusion phecode
626.4 Premenstrual tension syndromes Genitourinary 1.02 0.867 – 1.2 0.794 156 1546 exclusion phecode
626.8 Infertility, female Genitourinary 0.984 0.93 – 1.04 0.57 1330 13255 exclusion phecode
627 Menopausal and postmenopausal disorders Genitourinary 1.04 1.01 – 1.06 0.000777 9793 99738 exclusion phecode
627.1 Postmenopausal bleeding Genitourinary 1.04 1.02 – 1.06 0.00106 8516 86721 exclusion phecode
627.2 Symptomatic menopause Genitourinary 0.979 0.839 – 1.14 0.788 176 1772 exclusion phecode
627.3 Postmenopausal atrophic vaginitis Genitourinary 1.02 0.959 – 1.09 0.508 1065 10660 exclusion phecode
627.4 Premenopausal menorrhagia Genitourinary 1.03 0.909 – 1.16 0.667 289 2989 exclusion phecode
628 Ovarian cyst Genitourinary 1.05 1.02 – 1.08 0.00281 4542 45955 exclusion phecode
634 Miscarriage; stillbirth Pregnancy Complications 0.981 0.953 – 1.01 0.204 5105 35607 exclusion phecode
634.1 Missed abortion/Hydatidiform mole Pregnancy Complications 0.953 0.896 – 1.01 0.126 1111 11073 exclusion phecode
634.3 Ectopic pregnancy Pregnancy Complications 1.01 0.9 – 1.13 0.88 324 3241 exclusion phecode
635
Hemorrhage during pregnancy; childbirth and
Hemorrhage during pregnancy; childbirth and postpartum
 Pregnancy Complications 0.967 0.923 – 1.01 0.168 1922 17014 exclusion phecode
635.2
Antepartum hemorrhage, abruptio placentae, and
Antepartum hemorrhage, abruptio placentae, and placenta previa
 Pregnancy Complications 0.953 0.889 – 1.02 0.178 848 8440 exclusion phecode
635.3 Placenta previa and abruptio placenta Pregnancy Complications 0.967 0.912 – 1.03 0.262 1234 12059 exclusion phecode
636
Early or threatened labor; hemorrhage in early
Early or threatened labor; hemorrhage in early pregnancy
 Pregnancy Complications 0.994 0.951 – 1.04 0.769 2286 19568 exclusion phecode
636.2 Early onset of delivery Pregnancy Complications 0.971 0.893 – 1.06 0.487 593 6017 exclusion phecode
636.3 Hemorrhage in early pregnancy Pregnancy Complications 0.956 0.896 – 1.02 0.163 1049 10542 exclusion phecode
638 Other high-risk pregnancy Pregnancy Complications 0.84 0.658 – 1.07 0.161 67 686 exclusion phecode
642
Hypertension complicating pregnancy
Hypertension complicating pregnancy, childbirth, and the puerperium
 Pregnancy Complications 0.999 0.938 – 1.06 0.984 1053 10847 exclusion phecode
642.1 Preeclampsia and eclampsia Pregnancy Complications 1.07 0.953 – 1.21 0.241 289 2990 exclusion phecode
643 Excessive vomiting in pregnancy Pregnancy Complications 0.997 0.865 – 1.15 0.966 203 2106 exclusion phecode
643.1 Hyperemesis gravidarum Pregnancy Complications 0.944 0.8 – 1.11 0.499 145 1496 exclusion phecode
645 Late pregnancy and failed induction Pregnancy Complications 0.945 0.892 – 1 0.06 1221 12220 exclusion phecode
646 Other complications of pregnancy NEC Pregnancy Complications 0.974 0.932 – 1.02 0.253 2148 20439 exclusion phecode
647
Infectious and parasitic complications
Infectious and parasitic complications affecting pregnancy
 Pregnancy Complications 1.22 0.948 – 1.56 0.124 68 663 exclusion phecode
647.1
Infections of genitourinary tract during
Infections of genitourinary tract during pregnancy
 Pregnancy Complications 1.04 0.923 – 1.18 0.494 268 2698 exclusion phecode
649
Other conditions or status of the mother
Other conditions or status of the mother complicating pregnancy, childbirth, or the puerperium
 Pregnancy Complications 0.79 0.649 – 0.961 0.0182 107 1112 exclusion phecode
649.1
Diabetes or abnormal glucose tolerance
Diabetes or abnormal glucose tolerance complicating pregnancy
 Pregnancy Complications 1.14 0.865 – 1.5 0.354 50 1891 exclusion phecode
650 Normal delivery Pregnancy Complications 0.978 0.933 – 1.03 0.355 1892 18558 exclusion phecode
651 Multiple gestation Pregnancy Complications 0.948 0.848 – 1.06 0.345 338 3390 exclusion phecode
652
Malposition and malpresentation of fetus or
Malposition and malpresentation of fetus or obstruction
 Pregnancy Complications 1 0.951 – 1.05 0.997 1675 16191 exclusion phecode
653
Problems associated with amniotic cavity and
Problems associated with amniotic cavity and membranes
 Pregnancy Complications 1.01 0.956 – 1.07 0.709 1371 13371 exclusion phecode
654
Other and unspecified complications of birth
Other and unspecified complications of birth; puerperium affecting management of mother
 Pregnancy Complications 0.808 0.637 – 1.03 0.0797 72 727 exclusion phecode
655
Known or suspected fetal abnormality affecting
Known or suspected fetal abnormality affecting management of mother
 Pregnancy Complications 0.978 0.947 – 1.01 0.181 4192 28851 exclusion phecode
656 Other perinatal conditions of fetus or newborn Pregnancy Complications 1.01 0.833 – 1.23 0.889 105 1051 exclusion phecode
661 Fetal distress and abnormal forces of labor Pregnancy Complications 0.971 0.929 – 1.02 0.202 2210 18007 exclusion phecode
663
Umbilical cord complications during labor and
Umbilical cord complications during labor and delivery
 Pregnancy Complications 1.03 0.944 – 1.13 0.493 517 5194 exclusion phecode
665 Obstetrical/birth trauma Pregnancy Complications 0.957 0.929 – 0.986 0.00437 5235 28815 exclusion phecode
669 Complications of labor and delivery NEC Pregnancy Complications 0.954 0.915 – 0.994 0.025 2502 20734 exclusion phecode
671
Venous/cerebrovascular complications embolism
Venous/cerebrovascular complications embolism in pregnancy and the puerperium
 Pregnancy Complications 0.96 0.82 – 1.13 0.616 158 1586 exclusion phecode
674 Other complications of the puerperium NEC Pregnancy Complications 1 0.882 – 1.14 0.942 251 2547 exclusion phecode
676
Other disorders of the breast associated with
Other disorders of the breast associated with childbirth and disorders of lactation
 Pregnancy Complications 1.14 0.885 – 1.46 0.318 63 609 exclusion phecode
679 Complications of in utero procedures Dermatologic 0.866 0.651 – 1.15 0.323 51 514 exclusion phecode
681 Superficial cellulitis and abscess Dermatologic 1.02 0.996 – 1.05 0.0969 6104 67994 exclusion phecode
681.1 Cellulitis and abscess of fingers/toes Dermatologic 1.05 0.951 – 1.15 0.355 473 5322 exclusion phecode
681.2 Cellulitis and abscess of face/neck Dermatologic 1.03 0.94 – 1.13 0.507 474 4941 exclusion phecode
681.3 Cellulitis and abscess of arm/hand Dermatologic 1.01 0.983 – 1.04 0.388 4576 51689 exclusion phecode
681.5 Cellulitis and abscess of leg, except foot Dermatologic 1.01 0.984 – 1.05 0.345 4581 51745 exclusion phecode
681.6 Cellulitis and abscess of foot, toe Dermatologic 1.01 0.984 – 1.05 0.37 4541 51336 exclusion phecode
681.7 Cellulitis and abscess of trunk Dermatologic 1.06 0.973 – 1.16 0.178 524 5692 exclusion phecode
686
Other local infections of skin and subcutaneous
Other local infections of skin and subcutaneous tissue
 Dermatologic 0.973 0.915 – 1.03 0.382 1124 12646 exclusion phecode
686.1 Carbuncle and furuncle Dermatologic 1.02 0.977 – 1.07 0.328 1948 21676 exclusion phecode
686.3 Pilonidal cyst Dermatologic 1.02 0.933 – 1.12 0.649 524 5552 exclusion phecode
686.4 Pyogenic granuloma Dermatologic 1.02 0.916 – 1.14 0.682 328 3429 exclusion phecode
687 Symptoms affecting skin Dermatologic 1.01 0.916 – 1.1 0.91 498 5216 exclusion phecode
687.1 Rash and other nonspecific skin eruption Dermatologic 1 0.956 – 1.05 0.946 1945 20296 exclusion phecode
687.2 Localized superficial swelling, mass, or lump Dermatologic 1.09 0.963 – 1.24 0.171 264 2692 exclusion phecode
687.3 Changes in skin texture Dermatologic 0.917 0.75 – 1.12 0.398 103 1007 exclusion phecode
687.4 Disturbance of skin sensation Dermatologic 1 0.964 – 1.04 0.862 2637 27337 exclusion phecode
689 Disorder of skin and subcutaneous tissue NOS Dermatologic 0.999 0.971 – 1.03 0.933 5340 54233 exclusion phecode
690 Erythematosquamous dermatosis Dermatologic 1.13 0.873 – 1.47 0.348 63 652 exclusion phecode
690.1 Seborrheic dermatitis Dermatologic 1.07 0.782 – 1.46 0.683 46 494 exclusion phecode
691 Congenital anomalies of skin Dermatologic 1.01 0.836 – 1.23 0.889 112 1120 exclusion phecode
694 Dyschromia and Vitiligo Dermatologic 0.997 0.932 – 1.07 0.927 924 9323 exclusion phecode
694.1 Vitiligo Dermatologic 1.06 0.809 – 1.4 0.655 52 567 exclusion phecode
694.2 Other dyschromia Dermatologic 0.997 0.925 – 1.07 0.936 748 7415 exclusion phecode
694.3 Vascular disorders of skin Dermatologic 0.887 0.729 – 1.08 0.233 99 1104 exclusion phecode
695 Erythematous conditions Dermatologic 1.02 0.977 – 1.07 0.35 2170 22502 exclusion phecode
695.1 Toxic erythema Dermatologic 1.13 0.924 – 1.38 0.236 102 1042 exclusion phecode
695.2 Bullous dermatoses Dermatologic 0.941 0.782 – 1.13 0.522 121 1271 exclusion phecode
695.21 Dermatitis herpetiformis Dermatologic 0.975 0.738 – 1.29 0.859 51 526 exclusion phecode
695.22 Pemphigus and pemphigoid Dermatologic 0.855 0.662 – 1.1 0.23 64 682 exclusion phecode
695.3 Rosacea Dermatologic 1.04 0.918 – 1.18 0.545 283 2885 exclusion phecode
695.4 Lupus (localized and systemic) Dermatologic 0.989 0.89 – 1.1 0.841 391 3938 exclusion phecode
695.41 Cutaneous lupus erythematosus Dermatologic 0.944 0.784 – 1.14 0.545 124 1232 exclusion phecode
695.42 Systemic lupus erythematosus Dermatologic 0.98 0.873 – 1.1 0.733 323 3265 exclusion phecode
695.7 Prurigo and Lichen Dermatologic 1.04 0.964 – 1.13 0.297 706 7357 exclusion phecode
695.8 Other specified erythematous conditions Dermatologic 1.18 1.02 – 1.36 0.0256 210 2244 exclusion phecode
695.81 Erythema nodosum Dermatologic 1.22 0.961 – 1.55 0.102 71 730 exclusion phecode
695.9 Unspecified erythematous condition Dermatologic 0.953 0.861 – 1.06 0.354 417 4368 exclusion phecode
696 Psoriasis and related disorders Dermatologic 1.05 0.999 – 1.1 0.0558 1999 21181 exclusion phecode
696.4 Psoriasis Dermatologic 1.05 1 – 1.1 0.0511 1949 20688 exclusion phecode
696.41 Psoriasis vulgaris Dermatologic 1.04 0.986 – 1.1 0.146 1482 15771 exclusion phecode
696.42 Psoriatic arthropathy Dermatologic 1.03 0.95 – 1.12 0.466 627 6658 exclusion phecode
697 Sarcoidosis Dermatologic 1.1 1 – 1.21 0.0459 487 5093 exclusion phecode
698 Pruritus and related conditions Dermatologic 0.976 0.903 – 1.05 0.535 713 7402 exclusion phecode
700 Corns and callosities Dermatologic 0.949 0.837 – 1.08 0.417 268 2749 exclusion phecode
701
Other hypertrophic and atrophic conditions of
Other hypertrophic and atrophic conditions of skin
 Dermatologic 1 0.97 – 1.03 0.975 4339 44148 exclusion phecode
701.1 Keratoderma, acquired Dermatologic 1.03 0.823 – 1.3 0.779 81 797 exclusion phecode
701.2 Scar conditions and fibrosis of skin Dermatologic 0.99 0.947 – 1.03 0.637 2223 22237 exclusion phecode
701.3 Circumscribed scleroderma Dermatologic 1.19 0.908 – 1.57 0.205 54 587 exclusion phecode
701.4 Keloid scar Dermatologic 1.02 0.88 – 1.18 0.799 202 2074 exclusion phecode
701.5 Abnormal granulation tissue Dermatologic 0.949 0.859 – 1.05 0.304 422 4348 exclusion phecode
701.6 Acquired acanthosis nigricans Dermatologic 0.897 0.724 – 1.11 0.32 92 974 exclusion phecode
702
Degenerative skin conditions and other
Degenerative skin conditions and other dermatoses
 Dermatologic 1.02 0.99 – 1.05 0.212 5152 51237 exclusion phecode
702.1 Actinic keratosis Dermatologic 1.01 0.972 – 1.06 0.514 2428 24225 exclusion phecode
702.2 Seborrheic keratosis Dermatologic 1.02 0.98 – 1.06 0.345 2921 28890 exclusion phecode
703 Diseases of nail, NOS Dermatologic 0.977 0.872 – 1.09 0.683 320 3332 exclusion phecode
703.1 Ingrowing nail Dermatologic 0.989 0.92 – 1.06 0.766 838 9124 exclusion phecode
704 Diseases of hair and hair follicles Dermatologic 1.01 0.985 – 1.04 0.355 4979 49801 exclusion phecode
704.1 Alopecia Dermatologic 1.03 0.859 – 1.25 0.72 117 1225 exclusion phecode
704.8
Other specified diseases of hair and hair
Other specified diseases of hair and hair follicles
 Dermatologic 1.06 0.837 – 1.35 0.616 74 717 exclusion phecode
705 Disorders of sweat glands Dermatologic 0.981 0.848 – 1.13 0.797 201 2187 exclusion phecode
705.3 Hidradenitis Dermatologic 1 0.852 – 1.17 0.998 164 1796 exclusion phecode
705.8 Hyperhidrosis Dermatologic 1.05 0.963 – 1.15 0.252 540 5540 exclusion phecode
706 Diseases of sebaceous glands Dermatologic 1.02 0.992 – 1.04 0.199 7841 78625 exclusion phecode
706.1 Acne Dermatologic 0.95 0.752 – 1.2 0.67 73 733 exclusion phecode
706.2 Sebaceous cyst Dermatologic 1.02 0.999 – 1.05 0.0611 8282 83006 exclusion phecode
707 Chronic ulcer of skin Dermatologic 0.99 0.937 – 1.05 0.713 1374 18299 exclusion phecode
707.1 Decubitus ulcer Dermatologic 0.992 0.919 – 1.07 0.839 727 8446 exclusion phecode
709 Diffuse diseases of connective tissue Dermatologic 1.01 0.971 – 1.05 0.664 3018 32437 exclusion phecode
709.2 Sicca syndrome Dermatologic 1.07 0.971 – 1.17 0.178 479 4856 exclusion phecode
709.3 Systemic sclerosis Dermatologic 0.986 0.839 – 1.16 0.86 163 1671 exclusion phecode
709.6
Other specified diffuse diseases of connective
Other specified diffuse diseases of connective tissue
 Dermatologic 1.14 0.879 – 1.48 0.324 61 614 exclusion phecode
709.7 Unspecified diffuse connective tissue disease Dermatologic 1.01 0.968 – 1.05 0.664 2346 25597 exclusion phecode
710
Osteomyelitis, periostitis, and other
Osteomyelitis, periostitis, and other infections involving bone
 Musculoskeletal 1.03 0.932 – 1.14 0.574 427 5631 exclusion phecode
710.1 Osteomyelitis Musculoskeletal 1.09 0.978 – 1.2 0.123 387 5206 exclusion phecode
710.12 Chronic osteomyelitis Musculoskeletal 1.14 0.962 – 1.34 0.133 154 1841 exclusion phecode
710.19 Unspecified osteomyelitis Musculoskeletal 1.04 0.916 – 1.18 0.545 253 3710 exclusion phecode
711 Arthropathy associated with infections Musculoskeletal 0.995 0.894 – 1.11 0.933 368 3990 exclusion phecode
711.1 Pyogenic arthritis Musculoskeletal 1.02 0.903 – 1.16 0.736 282 3105 exclusion phecode
712 Infective connective tissue disorders Musculoskeletal 0.9 0.701 – 1.16 0.41 73 758 exclusion phecode
713
Arthropathy associated with other disorders
Arthropathy associated with other disorders classified elsewhere
 Musculoskeletal 0.916 0.735 – 1.14 0.438 81 1415 exclusion phecode
713.5
Arthropathy associated with neurological
Arthropathy associated with neurological disorders
 Musculoskeletal 1.49 0.789 – 2.81 0.219 6 620 exclusion phecode
714
Rheumatoid arthritis and other inflammatory
Rheumatoid arthritis and other inflammatory polyarthropathies
 Musculoskeletal 1.04 1.01 – 1.08 0.00827 4357 45792 exclusion phecode
714.1 Rheumatoid arthritis Musculoskeletal 1.04 1.01 – 1.08 0.0101 3953 41437 exclusion phecode
715 Other inflammatory spondylopathies Musculoskeletal 1.07 1.01 – 1.13 0.0153 1511 15657 exclusion phecode
715.1 Sacroiliitis NEC Musculoskeletal 1.01 0.837 – 1.23 0.884 106 1087 exclusion phecode
715.2 Ankylosing spondylitis Musculoskeletal 1.12 1.02 – 1.22 0.0141 567 5804 exclusion phecode
716 Other arthropathies Musculoskeletal 1.03 1.02 – 1.04 1.8e-06 34189 251534 exclusion phecode
716.1 Unspecified polyarthropathy or polyarthritis Musculoskeletal 1.04 1 – 1.08 0.046 3136 33100 exclusion phecode
716.2 Unspecified monoarthritis Musculoskeletal 1.03 1.01 – 1.05 0.0013 14255 146413 exclusion phecode
716.9 Arthropathy NOS Musculoskeletal 1.03 1.02 – 1.04 2.77e-06 32782 248570 exclusion phecode
717 Polymyalgia Rheumatica Musculoskeletal 1.02 0.962 – 1.09 0.451 1056 10755 exclusion phecode
720 Spinal stenosis Musculoskeletal 1.01 0.976 – 1.05 0.543 3327 34811 exclusion phecode
721 Spondylosis and allied disorders Musculoskeletal 1.01 0.989 – 1.04 0.286 7082 73821 exclusion phecode
721.1 Spondylosis without myelopathy Musculoskeletal 1.01 0.978 – 1.04 0.617 4568 47580 exclusion phecode
721.2 Spondylosis with myelopathy Musculoskeletal 1.06 0.899 – 1.25 0.497 162 1779 exclusion phecode
721.8 Other allied disorders of spine Musculoskeletal 1.03 0.918 – 1.15 0.634 322 3334 exclusion phecode
722 Intervertebral disc disorders Musculoskeletal 1.01 0.992 – 1.04 0.211 8258 85149 exclusion phecode
722.1 Displacement of intervertebral disc Musculoskeletal 1.06 0.965 – 1.17 0.225 469 4833 exclusion phecode
722.6 Degeneration of intervertebral disc Musculoskeletal 1.03 0.994 – 1.08 0.0979 2598 26876 exclusion phecode
722.8 Postlaminectomy syndrome Musculoskeletal 1.12 0.874 – 1.43 0.373 65 636 exclusion phecode
722.9 Other and unspecified disc disorder Musculoskeletal 0.995 0.963 – 1.03 0.737 4073 41781 exclusion phecode
723 Other disorders of cervical region Musculoskeletal 0.998 0.908 – 1.1 0.961 475 4864 exclusion phecode
723.1 Torticollis Musculoskeletal 0.929 0.753 – 1.15 0.492 100 1017 exclusion phecode
724 Other and unspecified disorders of back Musculoskeletal 1.02 0.969 – 1.06 0.513 1902 19394 exclusion phecode
724.1 Disorders of sacrum Musculoskeletal 1.08 0.971 – 1.2 0.161 383 3847 exclusion phecode
724.2 Disorders of coccyx Musculoskeletal 1.07 0.963 – 1.19 0.211 386 3872 exclusion phecode
724.8 Other symptoms referable to back Musculoskeletal 1.31 1.01 – 1.7 0.0386 57 606 exclusion phecode
724.9 Other unspecified back disorders Musculoskeletal 0.995 0.943 – 1.05 0.852 1490 15196 exclusion phecode
726 Peripheral enthesopathies and allied syndromes Musculoskeletal 1.03 1.01 – 1.05 0.00115 13398 138816 exclusion phecode
726.1 Enthesopathy Musculoskeletal 1.03 1 – 1.05 0.0192 8757 90645 exclusion phecode
726.2 Synoviopathy Musculoskeletal 1.08 0.965 – 1.22 0.175 308 3177 exclusion phecode
726.3 Bursitis Musculoskeletal 1.07 0.992 – 1.15 0.0809 765 8075 exclusion phecode
727 Other disorders of synovium, tendon, and bursa Musculoskeletal 1.03 1.01 – 1.06 0.0103 6854 69603 exclusion phecode
727.1 Synovitis and tenosynovitis Musculoskeletal 1.04 1 – 1.09 0.0405 2522 26036 exclusion phecode
727.2 Bursitis disorders Musculoskeletal 0.927 0.752 – 1.14 0.48 92 978 exclusion phecode
727.4 Ganglion and cyst of synovium, tendon, and bursa Musculoskeletal 1.02 0.982 – 1.06 0.297 2939 29661 exclusion phecode
727.5 Rupture of synovium Musculoskeletal 1.06 0.969 – 1.16 0.206 542 5507 exclusion phecode
727.6 Rupture of tendon, nontraumatic Musculoskeletal 1.04 0.929 – 1.17 0.496 330 3313 exclusion phecode
727.7 Contracture of tendon (sheath) Musculoskeletal 1.07 0.901 – 1.28 0.425 136 1360 exclusion phecode
728 Disorders of muscle, ligament, and fascia Musculoskeletal 1.05 1.01 – 1.08 0.0127 3324 34058 exclusion phecode
728.2 Laxity of ligament or hypermobility syndrome Musculoskeletal 1.01 0.908 – 1.12 0.894 395 3962 exclusion phecode
728.7 Fasciitis Musculoskeletal 1.05 1.01 – 1.08 0.0123 3444 35266 exclusion phecode
728.71
Contracture of palmar fascia [Dupuytren's
Contracture of palmar fascia [Dupuytren's disease]
 Musculoskeletal 1.05 1.01 – 1.09 0.00833 3141 32186 exclusion phecode
729 Other disorders of soft tissues Musculoskeletal 1.04 1.01 – 1.07 0.0127 5430 57052 exclusion phecode
729.1 Rheumatism, unspecified and fibrositis Musculoskeletal 0.973 0.909 – 1.04 0.429 906 9645 exclusion phecode
729.3 Panniculitis Musculoskeletal 0.941 0.762 – 1.16 0.57 93 966 exclusion phecode
731
Osteitis deformans and osteopathies associated
Osteitis deformans and osteopathies associated with other disorders classified elsewhere
 Musculoskeletal 1.04 0.917 – 1.19 0.521 257 2633 exclusion phecode
731.1 Osteitis deformans [Paget's disease of bone] Musculoskeletal 1.05 0.916 – 1.19 0.507 243 2487 exclusion phecode
732 Osteochondropathies Musculoskeletal 1.1 0.998 – 1.21 0.0543 447 4441 exclusion phecode
732.1 Juvenile osteochondrosis Musculoskeletal 1.07 0.925 – 1.25 0.353 195 1952 exclusion phecode
732.7 Osteochondritis dissecans Musculoskeletal 0.951 0.735 – 1.23 0.703 57 541 exclusion phecode
733 Other disorders of bone and cartilage Musculoskeletal 0.983 0.934 – 1.03 0.498 1668 16864 exclusion phecode
733.2 Cyst of bone Musculoskeletal 0.96 0.85 – 1.08 0.511 299 2943 exclusion phecode
733.4 Aseptic necrosis of bone Musculoskeletal 1.04 0.952 – 1.15 0.359 499 5091 exclusion phecode
733.6 Costochondritis Musculoskeletal 1.11 0.926 – 1.34 0.254 122 1218 exclusion phecode
733.8 Malunion and nonunion of fracture Musculoskeletal 1.01 0.948 – 1.07 0.823 1154 11673 exclusion phecode
733.9 Chondromalacia Musculoskeletal 1.12 0.919 – 1.36 0.261 114 1150 exclusion phecode
735 Acquired foot deformities Musculoskeletal 1 0.98 – 1.02 0.932 9254 91386 exclusion phecode
735.1 Flat foot Musculoskeletal 0.971 0.835 – 1.13 0.701 185 1810 exclusion phecode
735.2 Acquired toe deformities Musculoskeletal 1.02 0.987 – 1.05 0.283 4866 48115 exclusion phecode
735.21 Hammer toe (acquired) Musculoskeletal 1.04 0.989 – 1.09 0.129 1850 18337 exclusion phecode
735.23 Hallux rigidus Musculoskeletal 1.01 0.961 – 1.07 0.633 1498 14710 exclusion phecode
735.3 Hallux valgus (Bunion) Musculoskeletal 0.992 0.967 – 1.02 0.53 6437 63406 exclusion phecode
736 Other acquired deformities of limbs Musculoskeletal 1.04 0.988 – 1.1 0.13 1512 15264 exclusion phecode
736.2 Acquired deformities of finger Musculoskeletal 0.972 0.853 – 1.11 0.673 239 2337 exclusion phecode
737 Curvature of spine Musculoskeletal 0.971 0.912 – 1.03 0.367 1067 10715 exclusion phecode
737.3 Kyphoscoliosis and scoliosis Musculoskeletal 0.971 0.91 – 1.04 0.38 1008 10064 exclusion phecode
738 Other acquired musculoskeletal deformity Musculoskeletal 1.01 0.961 – 1.06 0.728 1753 18065 exclusion phecode
738.4 Acquired spondylolisthesis Musculoskeletal 1.02 0.961 – 1.07 0.583 1392 14362 exclusion phecode
739 Contracture of joint Musculoskeletal 0.955 0.867 – 1.05 0.343 454 4621 exclusion phecode
740 Osteoarthrosis Musculoskeletal 1.02 1.01 – 1.04 0.000649 25395 218276 exclusion phecode
740.1 Osteoarthritis; localized Musculoskeletal 1.03 1.01 – 1.05 0.000687 16122 159216 exclusion phecode
740.11 Osteoarthrosis, localized, primary Musculoskeletal 1.04 1.01 – 1.06 0.00127 8251 84140 exclusion phecode
740.12 Osteoarthrosis, localized, secondary Musculoskeletal 1 0.894 – 1.12 0.971 327 3292 exclusion phecode
740.2 Osteoarthrosis, generalized Musculoskeletal 1 0.917 – 1.09 0.993 551 5605 exclusion phecode
740.9 Osteoarthrosis NOS Musculoskeletal 1.01 0.994 – 1.03 0.16 11062 115758 exclusion phecode
741 Symptoms and disorders of the joints Musculoskeletal 1.03 0.992 – 1.07 0.123 3265 33551 exclusion phecode
741.1 Ankylosis of joint Musculoskeletal 1.25 1.01 – 1.54 0.0393 96 953 exclusion phecode
741.2 Stiffness of joint Musculoskeletal 1.02 0.938 – 1.11 0.621 569 5806 exclusion phecode
741.3 Difficulty in walking Musculoskeletal 0.915 0.763 – 1.1 0.342 126 1431 exclusion phecode
741.4 Joint effusions Musculoskeletal 1.06 0.999 – 1.12 0.0554 1283 13289 exclusion phecode
741.5 Hemarthrosis Musculoskeletal 1.09 0.888 – 1.34 0.404 101 1036 exclusion phecode
741.6 Villonodular synovitis Musculoskeletal 1.01 0.762 – 1.35 0.93 51 514 exclusion phecode
742 Derangement of joint, non-traumatic Musculoskeletal 1.03 0.988 – 1.07 0.166 2680 27102 exclusion phecode
742.1 Loose body in joint Musculoskeletal 1.06 0.942 – 1.19 0.343 315 3159 exclusion phecode
742.2
Pathological, developmental or recurrent
Pathological, developmental or recurrent dislocation
 Musculoskeletal 1.1 0.885 – 1.36 0.397 87 934 exclusion phecode
742.8 Articular cartilage disorder Musculoskeletal 1.03 0.933 – 1.13 0.583 459 4762 exclusion phecode
742.9 Other derangement of joint Musculoskeletal 1.03 0.981 – 1.08 0.246 1898 19016 exclusion phecode
743
Osteoporosis, osteopenia and pathological
Osteoporosis, osteopenia and pathological fracture
 Musculoskeletal 0.973 0.95 – 0.997 0.0294 7063 71598 exclusion phecode
743.1 Osteoporosis Musculoskeletal 0.97 0.945 – 0.996 0.0256 5975 60607 exclusion phecode
743.11 Osteoporosis NOS Musculoskeletal 0.963 0.936 – 0.991 0.0102 5187 52642 exclusion phecode
743.13 Other specified osteoporosis Musculoskeletal 0.976 0.888 – 1.07 0.609 487 4960 exclusion phecode
743.2 Pathologic fracture Musculoskeletal 1.02 0.927 – 1.12 0.72 470 4849 exclusion phecode
743.9
Osteopenia or other disorder of bone and
Osteopenia or other disorder of bone and cartilage
 Musculoskeletal 0.968 0.899 – 1.04 0.385 771 7736 exclusion phecode
745 Pain in joint Musculoskeletal 1.03 1 – 1.05 0.0226 7314 75549 exclusion phecode
747 Cardiac and circulatory congenital anomalies Congenital Anomalies 0.977 0.938 – 1.02 0.285 2444 26246 exclusion phecode
747.1 Cardiac congenital anomalies Congenital Anomalies 0.977 0.936 – 1.02 0.299 2282 24611 exclusion phecode
747.11 Cardiac shunt/ heart septal defect Congenital Anomalies 0.88 0.805 – 0.961 0.00467 552 5570 exclusion phecode
747.12 Valvular heart disease/ heart chambers Congenital Anomalies 0.958 0.835 – 1.1 0.538 222 2232 exclusion phecode
747.13 Congenital anomalies of great vessels Congenital Anomalies 1.03 0.98 – 1.09 0.227 1517 16840 exclusion phecode
747.2
Congenital anomalies of peripheral vascular
Congenital anomalies of peripheral vascular system
 Congenital Anomalies 0.931 0.786 – 1.1 0.404 154 1589 exclusion phecode
748 Anomalies of respiratory system, congenital Congenital Anomalies 1.21 0.914 – 1.61 0.182 49 479 exclusion phecode
749 Congenital anomalies of face and neck Congenital Anomalies 0.835 0.74 – 0.941 0.00306 282 2892 exclusion phecode
750 Digestive congenital anomalies Congenital Anomalies 0.923 0.851 – 1 0.0547 646 6422 exclusion phecode
750.1 Upper gastrointestinal congenital anomalies Congenital Anomalies 0.887 0.788 – 0.998 0.0464 304 3046 exclusion phecode
750.13 Congenital anomalies of mouth/tongue Congenital Anomalies 0.865 0.743 – 1.01 0.0621 182 1772 exclusion phecode
750.2 Lower gastrointestinal congenital anomalies Congenital Anomalies 0.957 0.855 – 1.07 0.444 338 3363 exclusion phecode
750.21 Congenital anomalies of intestine Congenital Anomalies 0.935 0.812 – 1.08 0.348 217 2115 exclusion phecode
750.22
Congenital anomaly of gallbladder, bile ducts
Congenital anomaly of gallbladder, bile ducts, liver, pancreas
 Congenital Anomalies 1.04 0.854 – 1.26 0.719 110 1119 exclusion phecode
751 Genitourinary congenital anomalies Congenital Anomalies 0.99 0.937 – 1.04 0.708 1418 14452 exclusion phecode
751.1 Congenital anomalies of genital organs Congenital Anomalies 1 0.927 – 1.09 0.925 661 6602 exclusion phecode
751.11 Congenital anomalies of female genital organs Congenital Anomalies 1.08 0.983 – 1.2 0.105 442 4394 exclusion phecode
751.12 Congenital anomalies of male genital organs Congenital Anomalies 0.871 0.756 – 1 0.057 202 2042 exclusion phecode
751.2 Congenital anomalies of urinary system Congenital Anomalies 0.99 0.919 – 1.07 0.786 759 7863 exclusion phecode
751.21 Cystic kidney disease Congenital Anomalies 0.919 0.827 – 1.02 0.118 380 3981 exclusion phecode
751.22 Other specified congenital anomalies of kidney Congenital Anomalies 1.03 0.915 – 1.16 0.639 301 3141 exclusion phecode
752 Nervous system congenital anomalies Congenital Anomalies 1.02 0.909 – 1.15 0.702 310 3151 exclusion phecode
752.1 Neural tube defects Congenital Anomalies 0.955 0.833 – 1.09 0.508 242 2440 exclusion phecode
752.11 Spina bifida Congenital Anomalies 0.968 0.833 – 1.12 0.666 201 2013 exclusion phecode
752.2
Other specified congenital anomalies of nervous
Other specified congenital anomalies of nervous system
 Congenital Anomalies 1.4 1.09 – 1.8 0.00768 71 739 exclusion phecode
753 Congenital anomalies of the eye Congenital Anomalies 1.04 0.852 – 1.26 0.727 120 1197 exclusion phecode
753.1 Congenital cataract and lens anomalies Congenital Anomalies 0.95 0.74 – 1.22 0.684 72 716 exclusion phecode
754 Congenital musculoskeletal deformities of spine Congenital Anomalies 1.1 0.895 – 1.35 0.373 103 1041 exclusion phecode
755 Congenital anomalies of limbs Congenital Anomalies 1.07 0.964 – 1.18 0.212 408 4087 exclusion phecode
755.1 Congenital deformities of feet Congenital Anomalies 1.06 0.917 – 1.23 0.414 193 1984 exclusion phecode
755.6
Other congenital anomalies of lower limb
Other congenital anomalies of lower limb, including pelvic girdle
 Congenital Anomalies 1.03 0.873 – 1.21 0.731 159 1556 exclusion phecode
755.61 Congenital hip dysplasia and deformity Congenital Anomalies 1.02 0.84 – 1.25 0.812 106 1033 exclusion phecode
756 Other congenital musculoskeletal anomalies Congenital Anomalies 0.957 0.878 – 1.04 0.32 553 5548 exclusion phecode
756.3
Congenital anomalies of muscle, tendon, fascia
Congenital anomalies of muscle, tendon, fascia, and connective tissue
 Congenital Anomalies 0.934 0.743 – 1.17 0.556 78 768 exclusion phecode
756.5 Congenital osteodystrophies Congenital Anomalies 1 0.904 – 1.11 0.976 408 4121 exclusion phecode
758 Chromosomal anomalies and genetic disorders Congenital Anomalies 0.897 0.757 – 1.06 0.211 142 1619 exclusion phecode
758.1 Chromosomal anomalies Congenital Anomalies 0.821 0.629 – 1.07 0.145 57 793 exclusion phecode
759 Other and unspecified congenital anomalies Congenital Anomalies 0.989 0.858 – 1.14 0.876 204 2055 exclusion phecode
759.1 Anomalies of endocrine glands, congenital Congenital Anomalies 0.997 0.804 – 1.24 0.977 91 912 exclusion phecode
760 Back pain Symptoms 1.02 0.998 – 1.04 0.0702 10118 105492 exclusion phecode
761 Cervicalgia Symptoms 1.05 0.996 – 1.1 0.0682 1629 16951 exclusion phecode
764 Sciatica Symptoms 1.04 0.991 – 1.08 0.12 2185 22486 exclusion phecode
766 Neuralgia, neuritis, and radiculitis NOS Symptoms 1.02 0.955 – 1.08 0.611 1070 11115 exclusion phecode
770 Myalgia and myositis unspecified Symptoms 0.953 0.874 – 1.04 0.279 569 5994 exclusion phecode
771 Musculoskeletal symptoms referable to limbs Symptoms 1.04 0.971 – 1.12 0.241 778 8187 exclusion phecode
771.1 Swelling of limb Symptoms 1.04 1.01 – 1.07 0.0199 4161 43631 exclusion phecode
772 Symptoms of the muscles Symptoms 1.04 0.955 – 1.14 0.355 584 6195 exclusion phecode
773 Pain in limb Symptoms 1.04 1.01 – 1.07 0.00447 5628 58848 exclusion phecode
780 Hypothermia/Chills Symptoms 1.08 0.91 – 1.29 0.368 140 1635 exclusion phecode
781
Symptoms involving nervous and musculoskeletal
Symptoms involving nervous and musculoskeletal systems
 Symptoms 1.01 0.964 – 1.07 0.604 1659 17686 exclusion phecode
782.3 Edema Symptoms 0.998 0.944 – 1.05 0.939 1365 15365 exclusion phecode
782.6 Pallor and flushing Symptoms 1.11 0.948 – 1.31 0.191 153 1650 exclusion phecode
783 Fever of unknown origin Symptoms 0.994 0.96 – 1.03 0.719 3539 36765 exclusion phecode
785 Abdominal pain Symptoms 1.01 0.997 – 1.02 0.136 37406 286103 exclusion phecode
788 Syncope and collapse Symptoms 1.02 0.997 – 1.04 0.088 8117 85154 exclusion phecode
789 Nausea and vomiting Symptoms 1.01 0.989 – 1.03 0.397 10410 109905 exclusion phecode
790 Nonspecific findings on examination of blood Symptoms 0.966 0.816 – 1.14 0.686 141 1405 exclusion phecode
790.1 Elevated sedimentation rate Symptoms 1.12 0.888 – 1.42 0.334 76 782 exclusion phecode
790.6 Other abnormal blood chemistry Symptoms 1.01 0.983 – 1.04 0.456 5705 58767 exclusion phecode
791 Gangrene Symptoms 1.07 0.967 – 1.19 0.184 382 5152 exclusion phecode
792
Abnormal Papanicolaou smear of cervix and
Abnormal Papanicolaou smear of cervix and cervical HPV
 Symptoms 0.842 0.681 – 1.04 0.112 95 925 exclusion phecode
793
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of musculoskeletal system
 Symptoms 0.802 0.663 – 0.97 0.0231 116 1249 exclusion phecode
793.2
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of other intrathoracic organs (echocardiogram, etc)
 Symptoms 1.03 0.944 – 1.13 0.48 520 5317 exclusion phecode
794
Abnormal results of other function studies
Abnormal results of other function studies (bladder, pancreas, placenta, spleen, etc)
 Symptoms 1.04 0.866 – 1.25 0.684 113 1158 exclusion phecode
797 Shock Symptoms 0.934 0.777 – 1.12 0.463 126 1455 exclusion phecode
797.1 Cardiogenic shock Symptoms 0.946 0.751 – 1.19 0.641 75 944 exclusion phecode
798 Malaise and fatigue Symptoms 1.01 0.973 – 1.05 0.59 3074 32254 exclusion phecode
798.1 Chronic fatigue syndrome Symptoms 1.04 0.955 – 1.14 0.35 548 5681 exclusion phecode
800 Fracture of lower limb Injuries & Poisonings 1.02 0.993 – 1.05 0.154 6478 66496 exclusion phecode
800.1 Fracture of neck of femur Injuries & Poisonings 0.948 0.902 – 0.997 0.0377 1668 17025 exclusion phecode
800.2 Fracture of unspecified part of femur Injuries & Poisonings 1.02 0.865 – 1.2 0.812 151 1587 exclusion phecode
800.3 Fracture of tibia and fibula Injuries & Poisonings 1.04 0.994 – 1.09 0.0927 2001 20477 exclusion phecode
800.4 Fracture of patella Injuries & Poisonings 1.06 0.982 – 1.15 0.136 709 7196 exclusion phecode
801 Fracture of ankle and foot Injuries & Poisonings 1.03 0.98 – 1.07 0.276 2048 20884 exclusion phecode
801.1 Fracture of foot Injuries & Poisonings 1.04 0.987 – 1.09 0.157 1708 17374 exclusion phecode
802 Fracture of pelvis Injuries & Poisonings 0.96 0.887 – 1.04 0.31 675 6757 exclusion phecode
803 Fracture of upper limb Injuries & Poisonings 0.972 0.95 – 0.995 0.0177 7835 78638 exclusion phecode
803.1 Fracture of humerus Injuries & Poisonings 1 0.953 – 1.06 0.884 1532 15970 exclusion phecode
803.2 Fracture of radius and ulna Injuries & Poisonings 0.951 0.924 – 0.979 0.000667 5004 49646 exclusion phecode
803.3 Fracture of clavicle or scapula Injuries & Poisonings 0.982 0.929 – 1.04 0.516 1422 14317 exclusion phecode
804 Fracture of hand or wrist Injuries & Poisonings 0.969 0.934 – 1.01 0.0918 3172 31635 exclusion phecode
805
Fracture of vertebral column without mention of
Fracture of vertebral column without mention of spinal cord injury
 Injuries & Poisonings 1.04 0.984 – 1.11 0.155 1253 12743 exclusion phecode
807 Fracture of ribs Injuries & Poisonings 0.948 0.879 – 1.02 0.164 723 7285 exclusion phecode
809 Fracture of unspecified bones Injuries & Poisonings 0.987 0.929 – 1.05 0.656 1195 12215 exclusion phecode
817 Concussion Injuries & Poisonings 1.02 0.886 – 1.16 0.823 228 2295 exclusion phecode
818 Intracranial hemorrhage (injury) Injuries & Poisonings 0.932 0.848 – 1.02 0.144 469 4844 exclusion phecode
819
Skull and face fracture and other intercranial
Skull and face fracture and other intercranial injury
 Injuries & Poisonings 1.01 0.972 – 1.05 0.587 2780 27999 exclusion phecode
823 Torus fracture Injuries & Poisonings 1.03 0.979 – 1.09 0.24 1553 15891 exclusion phecode
830 Dislocation Injuries & Poisonings 1 0.956 – 1.05 0.95 1981 19750 exclusion phecode
835 Internal derangement of knee Injuries & Poisonings 1.03 1.01 – 1.05 0.000547 14368 143917 exclusion phecode
836 Traumatic arthropathy Injuries & Poisonings 1.15 1.04 – 1.26 0.00407 489 4961 exclusion phecode
840 Sprains and strains Injuries & Poisonings 1.07 0.97 – 1.17 0.183 455 4463 exclusion phecode
850 Hemorrhage or hematoma complicating a procedure Injuries & Poisonings 1.03 1 – 1.07 0.0277 4831 49685 exclusion phecode
851
Complications of transplants and reattached
Complications of transplants and reattached limbs
 Injuries & Poisonings 0.959 0.805 – 1.14 0.633 142 1484 exclusion phecode
853 Complication of colostomy or enterostomy Injuries & Poisonings 1.07 0.967 – 1.17 0.202 445 4715 exclusion phecode
854
Complications of cardiac/vascular device
Complications of cardiac/vascular device, implant, and graft
 Injuries & Poisonings 1.02 0.97 – 1.08 0.413 1490 16959 exclusion phecode
857
Mechanical complication of unspecified
Mechanical complication of unspecified genitourinary device, implant, and graft
 Injuries & Poisonings 0.992 0.933 – 1.06 0.804 1115 11686 exclusion phecode
858 Complication of internal orthopedic device Injuries & Poisonings 1.03 0.993 – 1.07 0.105 2928 29749 exclusion phecode
859
Complication due to other implant and internal
Complication due to other implant and internal device
 Injuries & Poisonings 1.01 0.972 – 1.05 0.638 2992 30725 exclusion phecode
860 Bone marrow or stem cell transplant Neoplasms 0.964 0.741 – 1.25 0.783 63 644 exclusion phecode
870 Open wounds of head; neck; and trunk Injuries & Poisonings 0.984 0.949 – 1.02 0.378 3232 32981 exclusion phecode
870.1 Open wound or laceration of eye or eyelid Injuries & Poisonings 0.9 0.792 – 1.02 0.11 253 2529 exclusion phecode
870.2 Open wound of ear Injuries & Poisonings 0.947 0.813 – 1.1 0.481 179 1833 exclusion phecode
870.3 Other open wound of head and face Injuries & Poisonings 0.976 0.938 – 1.02 0.238 2688 27359 exclusion phecode
870.4 Open wound of nose and sinus Injuries & Poisonings 0.92 0.798 – 1.06 0.248 205 2060 exclusion phecode
870.6 Open wound of neck Injuries & Poisonings 0.884 0.691 – 1.13 0.325 62 648 exclusion phecode
871 Open wounds of extremities Injuries & Poisonings 0.997 0.965 – 1.03 0.877 3818 38378 exclusion phecode
871.1 Open wound of hand except finger(s) Injuries & Poisonings 0.993 0.745 – 1.33 0.964 48 492 exclusion phecode
871.2 Open wound of finger(s) Injuries & Poisonings 1.27 1.02 – 1.59 0.0327 85 831 exclusion phecode
871.3 Open wound of foot except toe(s) alone Injuries & Poisonings 1.07 0.905 – 1.25 0.45 152 1697 exclusion phecode
872 Traumatic amputation Injuries & Poisonings 0.94 0.852 – 1.04 0.217 445 4452 exclusion phecode
873 Broken tooth Injuries & Poisonings 1.01 0.879 – 1.16 0.879 206 2153 exclusion phecode
874 Complication of amputation stump Injuries & Poisonings 0.982 0.818 – 1.18 0.846 118 1601 exclusion phecode
905
Late effects of musculoskeletal and connective
Late effects of musculoskeletal and connective tissue injuries
 Injuries & Poisonings 1.05 0.888 – 1.24 0.568 147 1473 exclusion phecode
907 Injuries to the nervous system Injuries & Poisonings 0.991 0.935 – 1.05 0.771 1248 12415 exclusion phecode
915 Superficial injury without mention of infection Injuries & Poisonings 1 0.969 – 1.04 0.898 3823 40191 exclusion phecode
916 Contusion Injuries & Poisonings 1 0.946 – 1.06 0.974 1326 13662 exclusion phecode
930 Allergic reaction to food Injuries & Poisonings 1.06 0.904 – 1.25 0.47 166 1721 exclusion phecode
938 Dermatitis due to solar radiation Injuries & Poisonings 0.873 0.784 – 0.973 0.0137 363 3639 exclusion phecode
938.2 Chronic dermatitis due to solar radiation Injuries & Poisonings 0.852 0.743 – 0.976 0.0209 236 2354 exclusion phecode
939
Atopic/contact dermatitis due to other or
Atopic/contact dermatitis due to other or unspecified
 Dermatologic 0.996 0.95 – 1.04 0.853 1938 19711 exclusion phecode
941 Adverse reaction to serum or vaccine Injuries & Poisonings 0.97 0.842 – 1.12 0.674 204 2116 exclusion phecode
942 Infusion and transfusion reaction Injuries & Poisonings 1.17 0.957 – 1.44 0.125 98 986 exclusion phecode
946 Anaphylactic shock NOS Injuries & Poisonings 1.01 0.925 – 1.11 0.771 487 5239 exclusion phecode
947 Urticaria Injuries & Poisonings 1.03 0.927 – 1.15 0.546 348 3538 exclusion phecode
949 Allergies, other Injuries & Poisonings 0.984 0.885 – 1.1 0.772 367 3816 exclusion phecode
952
Spinal cord injury without evidence of spinal
Spinal cord injury without evidence of spinal bone injury
 Injuries & Poisonings 0.978 0.88 – 1.09 0.686 386 3967 exclusion phecode
957 Injury to other and unspecified nerves Injuries & Poisonings 1.11 0.975 – 1.27 0.113 248 2544 exclusion phecode
958
Certain early complications of trauma or
Certain early complications of trauma or procedure
 Injuries & Poisonings 1.02 0.925 – 1.13 0.687 447 4626 exclusion phecode
958.1 Postoperative shock Injuries & Poisonings 1.13 0.818 – 1.57 0.449 43 509 exclusion phecode
958.2 Traumatic and surgical subcutaneous emphysema Injuries & Poisonings 1.17 0.919 – 1.48 0.205 70 685 exclusion phecode
960 Poisoning by antibiotics Injuries & Poisonings 1.01 0.998 – 1.03 0.0885 16634 172453 exclusion phecode
960.2 Allergy/adverse effect of penicillin Injuries & Poisonings 1.02 0.998 – 1.03 0.0799 14535 150937 exclusion phecode
961 Poisoning by other anti-infectives Injuries & Poisonings 0.975 0.88 – 1.08 0.637 380 3984 exclusion phecode
961.1 Poisoning/allergy of sulfonamides Injuries & Poisonings 0.97 0.903 – 1.04 0.403 806 8332 exclusion phecode
962 Poisoning by hormones and synthetic substitutes Injuries & Poisonings 1.09 0.972 – 1.23 0.137 315 3517 exclusion phecode
962.3
Hormones and synthetic substitutes causing
Hormones and synthetic substitutes causing adverse effects in therapeutic use
 Injuries & Poisonings 1.09 0.973 – 1.23 0.133 307 3449 exclusion phecode
963 Poisoning by primarily systemic agents Injuries & Poisonings 1.14 0.992 – 1.31 0.0642 210 2118 exclusion phecode
964
Poisoning by agents primarily affecting blood
Poisoning by agents primarily affecting blood constituents
 Injuries & Poisonings 0.98 0.858 – 1.12 0.759 240 2617 exclusion phecode
964.1 Anticoagulants causing adverse effects Injuries & Poisonings 0.963 0.843 – 1.1 0.582 234 2561 exclusion phecode
965
Poisoning by analgesics, antipyretics, and
Poisoning by analgesics, antipyretics, and antirheumatics
 Injuries & Poisonings 1.04 1.01 – 1.07 0.00785 5530 57958 exclusion phecode
965.1
Opiates and related narcotics causing adverse
Opiates and related narcotics causing adverse effects in therapeutic use
 Injuries & Poisonings 1.04 0.973 – 1.1 0.271 1038 10963 exclusion phecode
965.2
Antirheumatics causing adverse effects in
Antirheumatics causing adverse effects in therapeutic use
 Injuries & Poisonings 1 0.911 – 1.11 0.929 433 4576 exclusion phecode
965.3
Salicylates causing adverse effects in
Salicylates causing adverse effects in therapeutic use
 Injuries & Poisonings 1.03 0.921 – 1.15 0.624 357 3825 exclusion phecode
966
Poisoning by anticonvulsants and
Poisoning by anticonvulsants and anti-Parkinsonism drugs
 Injuries & Poisonings 1 0.91 – 1.1 0.964 467 4894 exclusion phecode
967
Adverse effects of sedatives or other central
Adverse effects of sedatives or other central nervous system depressants and anesthetics
 Injuries & Poisonings 1 0.918 – 1.1 0.949 542 5559 exclusion phecode
969 Poisoning by psychotropic agents Injuries & Poisonings 1.03 0.986 – 1.09 0.168 1767 18683 exclusion phecode
971
Poisoning by drugs primarily affecting the
Poisoning by drugs primarily affecting the autonomic nervous system
 Injuries & Poisonings 1.09 0.93 – 1.27 0.293 168 1828 exclusion phecode
972
Poisoning by agents primarily affecting the
Poisoning by agents primarily affecting the cardiovascular system
 Injuries & Poisonings 1 0.875 – 1.15 0.981 227 2590 exclusion phecode
972.6 Antihypertensive agents causing adverse effects Injuries & Poisonings 1.14 0.884 – 1.46 0.316 70 809 exclusion phecode
973
Poisoning by agents primarily affecting the
Poisoning by agents primarily affecting the gastrointestinal system
 Injuries & Poisonings 1.05 0.847 – 1.29 0.677 96 1021 exclusion phecode
974
Poisoning by water, mineral, and uric acid
Poisoning by water, mineral, and uric acid metabolism drugs
 Injuries & Poisonings 1.05 0.84 – 1.32 0.658 83 947 exclusion phecode
975
Poisoning by agents primarily acting on the
Poisoning by agents primarily acting on the smooth and skeletal muscles and respiratory system
 Injuries & Poisonings 0.895 0.685 – 1.17 0.413 58 611 exclusion phecode
976
Poisoning by agents primarily affecting skin &
Poisoning by agents primarily affecting skin & mucous membrane, ophthalmological, otorhinolaryngological, & dental drugs
 Injuries & Poisonings 0.938 0.706 – 1.25 0.656 52 555 exclusion phecode
977 Personal history of allergy to medicinal agents Injuries & Poisonings 0.997 0.865 – 1.15 0.968 215 2208 exclusion phecode
979 Adverse drug events and drug allergies Injuries & Poisonings 0.973 0.897 – 1.06 0.515 636 6637 exclusion phecode
981
Toxic effect of (non-ethyl) alcohol and
Toxic effect of (non-ethyl) alcohol and petroleum and other solvents
 Injuries & Poisonings 1.04 0.888 – 1.21 0.655 182 1903 exclusion phecode
986 Toxic effect of carbon monoxide Injuries & Poisonings 1.07 0.826 – 1.4 0.592 58 584 exclusion phecode
987 Toxic effect of other gases, fumes, or vapors Injuries & Poisonings 1.15 0.921 – 1.44 0.217 93 988 exclusion phecode
988 Toxic effect of noxious substances eaten as food Injuries & Poisonings 0.884 0.725 – 1.08 0.226 102 1060 exclusion phecode
989
Toxic effect of other substances, chiefly
Toxic effect of other substances, chiefly nonmedicinal as to source
 Injuries & Poisonings 0.841 0.675 – 1.05 0.123 86 840 exclusion phecode
990 Effects radiation NOS Injuries & Poisonings 0.977 0.94 – 1.01 0.229 2856 29168 exclusion phecode
994 Sepsis and SIRS Injuries & Poisonings 1.03 0.989 – 1.07 0.151 2636 28313 exclusion phecode
994.2 Sepsis Injuries & Poisonings 1.03 0.989 – 1.07 0.151 2636 28313 exclusion phecode
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