Departments of Anesthesiology and Biostatistics | University of Michigan

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Scores Total cholesterol (IRNT) Michigan Genomics Initiative Freeze 3 (MGI) PheWAS analysis

Total cholesterol (IRNT) — Michigan Genomics Initiative Freeze 3 (MGI) PRS PheWAS

PRS model
PRS ID exprsweb-totalcholesterol-30690-irnt-plink-mgi-freeze3-20211120Legacy PLINKC+T (GT)UK Biobank GWAS

Evaluation cohort: Michigan Genomics Initiative Freeze 3 (MGI).

This page pairs the PheWAS plot with the full sortable table for the all-subject and exclusion scans.

Read the all-subject and exclusion scans separately. The combined view is only a browsing aid, and the selected-phecode panel below is only meaningful when the same phecode exists in both scans.

ExPRS exclusion definition

Exclusion cohort: normal-range subset (0.01-200).

For this ExPRS, the exclusion sensitivity scan keeps only the study's normal-range subset for Total cholesterol (IRNT) (0.01-200) before rerunning the PheWAS. This is an exposure-based sensitivity analysis rather than a diagnosis-based exclusion.

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Signal overview

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139 rows visible 16 categories
Phecode Description Category OR 95% CI P value Cases Controls Analysis Link
008 Intestinal infection Infectious Diseases 0.98 0.943 – 1.02 0.305 3004 29292 all phecode
008.5 Bacterial enteritis Infectious Diseases 0.986 0.93 – 1.04 0.63 1322 13162 all phecode
008.52 Intestinal infection due to C. difficile Infectious Diseases 1.01 0.943 – 1.08 0.839 1046 10455 all phecode
008.6 Viral Enteritis Infectious Diseases 0.98 0.908 – 1.06 0.591 770 7676 all phecode
010 Tuberculosis Infectious Diseases 0.955 0.835 – 1.09 0.5 244 2425 all phecode
031 Diseases due to other mycobacteria Infectious Diseases 0.907 0.727 – 1.13 0.39 86 855 all phecode
038 Septicemia Infectious Diseases 1 0.963 – 1.05 0.871 2582 24779 all phecode
038.1 Gram negative septicemia Infectious Diseases 0.954 0.874 – 1.04 0.294 568 5629 all phecode
038.2 Gram positive septicemia Infectious Diseases 0.969 0.845 – 1.11 0.649 235 2350 all phecode
038.3 Bacteremia Infectious Diseases 0.991 0.933 – 1.05 0.758 1210 12079 all phecode
041 Bacterial infection NOS Infectious Diseases 1 0.976 – 1.03 0.779 5750 38799 all phecode
041.1 Staphylococcus infections Infectious Diseases 0.969 0.921 – 1.02 0.217 1707 16977 all phecode
041.11 Methicillin sensitive Staphylococcus aureus Infectious Diseases 0.963 0.898 – 1.03 0.282 920 9192 all phecode
041.12 Methicillin resistant Staphylococcus aureus Infectious Diseases 0.967 0.897 – 1.04 0.384 783 7812 all phecode
041.2 Streptococcus infection Infectious Diseases 0.993 0.943 – 1.05 0.781 1632 16287 all phecode
041.21 Rheumatic fever / chorea Infectious Diseases 1.01 0.892 – 1.15 0.842 257 2554 all phecode
041.4 E. coli Infectious Diseases 1.04 0.98 – 1.11 0.189 1175 11680 all phecode
041.8 H. pylori Infectious Diseases 0.944 0.83 – 1.07 0.384 257 2521 all phecode
041.9 Infection with drug-resistant microorganisms Infectious Diseases 1.04 0.931 – 1.15 0.521 387 3864 all phecode
053 Herpes zoster Infectious Diseases 1.01 0.954 – 1.06 0.797 1560 15184 all phecode
053.1 Herpes zoster with nervous system complications Infectious Diseases 0.893 0.775 – 1.03 0.118 220 2169 all phecode
054 Herpes simplex Infectious Diseases 0.999 0.948 – 1.05 0.971 1593 15600 all phecode
070 Viral hepatitis Infectious Diseases 1.01 0.938 – 1.09 0.814 829 8280 all phecode
070.1 Viral hepatitis A Infectious Diseases 1 0.801 – 1.26 0.982 87 860 all phecode
070.2 Viral hepatitis B Infectious Diseases 0.964 0.837 – 1.11 0.617 215 2138 all phecode
070.3 Viral hepatitis C Infectious Diseases 0.981 0.895 – 1.07 0.675 528 5280 all phecode
070.4 Chronic hepatitis Infectious Diseases 1 0.862 – 1.16 0.998 197 1964 all phecode
070.9 Hepatitis NOS Infectious Diseases 0.992 0.932 – 1.06 0.801 1145 11381 all phecode
071 Human immunodeficiency virus [HIV] disease Infectious Diseases 1.26 1.05 – 1.5 0.0111 145 1450 all phecode
071.1 HIV infection, symptomatic Infectious Diseases 1.36 1.12 – 1.66 0.00227 117 1163 all phecode
078 Viral warts & HPV Infectious Diseases 1.01 0.971 – 1.04 0.72 3434 29624 all phecode
079 Viral infection Infectious Diseases 1.03 1 – 1.06 0.0407 6664 35342 all phecode
079.1 Varicella infection Infectious Diseases 1.03 0.99 – 1.06 0.158 3793 31251 all phecode
079.2 Infectious mononucleosis Infectious Diseases 1.07 0.937 – 1.21 0.336 283 2723 all phecode
079.9 Viremia, NOS Infectious Diseases 1.04 0.965 – 1.12 0.309 838 8253 all phecode
080 Postoperative infection Infectious Diseases 0.978 0.939 – 1.02 0.299 2619 26065 all phecode
081
Infection/inflammation of internal prosthetic
Infection/inflammation of internal prosthetic device; implant; and graft
 Infectious Diseases 0.953 0.905 – 1 0.0745 1589 15884 all phecode
090
Sexually transmitted infections (not HIV or
Sexually transmitted infections (not HIV or hepatitis)
 Infectious Diseases 1.07 1 – 1.15 0.0473 965 9630 all phecode
110 Dermatophytosis / Dermatomycosis Infectious Diseases 0.984 0.949 – 1.02 0.389 3544 30054 all phecode
110.1 Dermatophytosis Infectious Diseases 0.983 0.947 – 1.02 0.385 3241 27244 all phecode
110.11 Dermatophytosis of nail Infectious Diseases 0.984 0.939 – 1.03 0.515 2044 16765 all phecode
110.12 Althete's foot Infectious Diseases 1 0.933 – 1.08 0.96 899 8043 all phecode
110.13 Dermatophytosis of the body Infectious Diseases 1.02 0.947 – 1.1 0.595 790 7827 all phecode
110.2 Dermatomycoses Infectious Diseases 0.948 0.853 – 1.05 0.32 398 3971 all phecode
112 Candidiasis Infectious Diseases 0.988 0.954 – 1.02 0.484 3685 30495 all phecode
112.3 Candidiasis of skin and nails Infectious Diseases 1 0.927 – 1.09 0.931 682 6732 all phecode
117 Mycoses Infectious Diseases 0.991 0.91 – 1.08 0.839 608 6069 all phecode
117.1 Histoplasmosis Infectious Diseases 1.05 0.834 – 1.33 0.659 81 801 all phecode
117.4 Aspergillosis Infectious Diseases 1.17 0.978 – 1.4 0.0868 140 1387 all phecode
130 Spirochetal infection Infectious Diseases 1.05 0.893 – 1.23 0.571 168 1677 all phecode
130.1 Lyme disease Infectious Diseases 1.13 0.938 – 1.37 0.198 116 1160 all phecode
131 Protozoan infection Infectious Diseases 1.04 0.801 – 1.35 0.763 61 610 all phecode
132 Infestation (lice, mites) Infectious Diseases 0.869 0.749 – 1.01 0.0656 195 1948 all phecode
134 Helminthiases Infectious Diseases 0.905 0.719 – 1.14 0.396 83 812 all phecode
134.1 Intestinal helminthiases Infectious Diseases 0.863 0.646 – 1.15 0.318 53 513 all phecode
136 Other infectious and parasitic diseases Infectious Diseases 1 0.965 – 1.04 0.969 3279 32486 all phecode
145 Cancer of mouth Neoplasms 0.949 0.899 – 1 0.0601 1481 14725 all phecode
145.1 Cancer of lip Neoplasms 0.787 0.626 – 0.99 0.0407 76 750 all phecode
145.2 Cancer of tongue Neoplasms 0.947 0.872 – 1.03 0.191 645 6430 all phecode
145.3 Cancer of major salivary glands Neoplasms 0.991 0.887 – 1.11 0.872 361 3597 all phecode
145.4 Cancer of the gums Neoplasms 0.907 0.772 – 1.07 0.235 166 1632 all phecode
145.5 Cancer of the mouth floor Neoplasms 0.975 0.843 – 1.13 0.73 206 2048 all phecode
149 Cancer of larynx, pharynx, nasal cavities Neoplasms 0.959 0.905 – 1.02 0.16 1290 12873 all phecode
149.1 Cancer of oropharynx Neoplasms 1 0.897 – 1.12 0.973 350 3499 all phecode
149.2 Cancer of nasopharynx Neoplasms 0.875 0.713 – 1.07 0.203 100 1000 all phecode
149.3 Cancer of hypopharynx Neoplasms 1.15 0.922 – 1.44 0.213 82 819 all phecode
149.4 Cancer of larynx Neoplasms 1.02 0.915 – 1.13 0.757 386 3857 all phecode
149.5
Hx of malignant neoplasm of oral cavity and
Hx of malignant neoplasm of oral cavity and pharynx
 Neoplasms 0.893 0.817 – 0.976 0.0126 552 5505 all phecode
149.9 Cancer of of nasal cavities Neoplasms 1 0.879 – 1.15 0.946 240 2398 all phecode
150 Cancer of esophagus Neoplasms 1.02 0.923 – 1.13 0.71 433 4315 all phecode
151 Cancer of stomach Neoplasms 1.04 0.944 – 1.14 0.442 498 4962 all phecode
153 Colorectal cancer Neoplasms 1.03 0.977 – 1.09 0.259 1458 14383 all phecode
153.2 Colon cancer Neoplasms 1.05 0.987 – 1.12 0.123 1160 11472 all phecode
153.3
Malignant neoplasm of rectum, rectosigmoid
Malignant neoplasm of rectum, rectosigmoid junction, and anus
 Neoplasms 1.02 0.951 – 1.1 0.529 815 8093 all phecode
155 Cancer of liver and intrahepatic bile duct Neoplasms 1.01 0.923 – 1.11 0.77 511 5097 all phecode
155.1 Malignant neoplasm of liver, primary Neoplasms 1.04 0.921 – 1.16 0.559 344 3433 all phecode
157 Pancreatic cancer Neoplasms 0.943 0.86 – 1.03 0.209 503 5005 all phecode
158
Neoplasm of unspecified nature of digestive
Neoplasm of unspecified nature of digestive system
 Neoplasms 0.951 0.903 – 1 0.0598 1623 15759 all phecode
159
Malignant neoplasm of other and ill-defined
Malignant neoplasm of other and ill-defined sites within the digestive organs and peritoneum
 Neoplasms 1 0.956 – 1.05 0.871 1818 17869 all phecode
159.2
Malignant neoplasm of small intestine
Malignant neoplasm of small intestine, including duodenum
 Neoplasms 1.22 1.06 – 1.41 0.00636 221 2206 all phecode
159.3
Malignant neoplasm of gallbladder and
Malignant neoplasm of gallbladder and extrahepatic bile ducts
 Neoplasms 0.871 0.738 – 1.03 0.0997 158 1578 all phecode
159.4
Malignant neoplasm of retroperitoneum and
Malignant neoplasm of retroperitoneum and peritoneum
 Neoplasms 1.01 0.89 – 1.14 0.913 293 2920 all phecode
164 Cancer of intrathoracic organs Neoplasms 1 0.839 – 1.19 1 133 1324 all phecode
165 Cancer within the respiratory system Neoplasms 0.972 0.918 – 1.03 0.323 1336 13340 all phecode
165.1 Cancer of bronchus; lung Neoplasms 0.953 0.894 – 1.02 0.14 1057 10552 all phecode
170 Cancer of bone and connective tissue Neoplasms 0.987 0.939 – 1.04 0.593 1792 17850 all phecode
170.1 Bone cancer Neoplasms 0.949 0.88 – 1.02 0.173 773 7690 all phecode
170.2 Cancer of connective tissue Neoplasms 0.988 0.932 – 1.05 0.691 1266 12632 all phecode
172 Skin cancer Neoplasms 0.991 0.967 – 1.02 0.492 8608 33186 all phecode
172.1 Melanomas of skin, dx or hx Neoplasms 0.994 0.964 – 1.02 0.695 5330 30106 all phecode
172.11 Melanomas of skin Neoplasms 0.992 0.955 – 1.03 0.691 3100 25064 all phecode
172.2 Other non-epithelial cancer of skin Neoplasms 0.982 0.955 – 1.01 0.186 7095 30462 all phecode
172.21 Basal cell carcinoma Neoplasms 1.01 0.977 – 1.05 0.481 3690 23868 all phecode
172.22 Squamous cell carcinoma Neoplasms 0.997 0.954 – 1.04 0.89 2414 17683 all phecode
172.3 Carcinoma in situ of skin Neoplasms 1.03 0.97 – 1.08 0.375 1482 12326 all phecode
173 Neoplasm of uncertain behavior of skin Neoplasms 0.978 0.933 – 1.03 0.357 1997 18755 all phecode
174 Breast cancer Neoplasms 1.01 0.967 – 1.05 0.767 3186 15514 all phecode
174.1 Breast cancer [female] Neoplasms 1.02 0.975 – 1.06 0.472 3036 14701 all phecode
174.11 Malignant neoplasm of female breast Neoplasms 1.02 0.978 – 1.06 0.384 2991 14639 all phecode
174.3 Neoplasm of uncertain behavior of breast Neoplasms 1.04 0.91 – 1.19 0.552 233 2307 all phecode
175 Acquired absence of breast Neoplasms 0.999 0.931 – 1.07 0.97 919 8920 all phecode
180 Cervical cancer and dysplasia Neoplasms 0.992 0.938 – 1.05 0.791 1431 12185 all phecode
180.1 Cervical cancer Neoplasms 0.939 0.856 – 1.03 0.188 500 4982 all phecode
180.3
Cervical intraepithelial neoplasia [CIN]
Cervical intraepithelial neoplasia [CIN] [Cervical dysplasia]
 Neoplasms 0.995 0.932 – 1.06 0.874 1048 9323 all phecode
182 Malignant neoplasm of uterus Neoplasms 0.945 0.876 – 1.02 0.141 765 7613 all phecode
184 Cancer of other female genital organs Neoplasms 0.989 0.931 – 1.05 0.729 1191 11592 all phecode
184.1
Malignant neoplasm of ovary and other uterine
Malignant neoplasm of ovary and other uterine adnexa
 Neoplasms 0.963 0.882 – 1.05 0.397 573 5719 all phecode
184.11 Malignant neoplasm of ovary Neoplasms 0.995 0.9 – 1.1 0.927 432 4309 all phecode
184.2
Cancer of other female genital organs
Cancer of other female genital organs (excluding uterus and ovary)
 Neoplasms 0.982 0.902 – 1.07 0.685 608 6057 all phecode
185 Cancer of prostate Neoplasms 1 0.958 – 1.04 0.991 2901 10342 all phecode
187 Cancer of other male genital organs Neoplasms 1.03 0.918 – 1.16 0.597 339 3384 all phecode
187.1
Malignant neoplasm of unspecified male genital
Malignant neoplasm of unspecified male genital organ
 Neoplasms 0.992 0.807 – 1.22 0.938 115 1141 all phecode
187.2 Malignant neoplasm of testis Neoplasms 0.997 0.851 – 1.17 0.968 183 1830 all phecode
187.8
Neoplasm of uncertain behavior of male genital
Neoplasm of uncertain behavior of male genital organs
 Neoplasms 1.05 0.789 – 1.39 0.757 57 562 all phecode
189
Cancer of urinary organs (incl. kidney and
Cancer of urinary organs (incl. kidney and bladder)
 Neoplasms 0.996 0.958 – 1.04 0.861 2923 23541 all phecode
189.1 Cancer of kidney and renal pelvis Neoplasms 0.992 0.939 – 1.05 0.787 1450 14437 all phecode
189.11 Malignant neoplasm of kidney, except pelvis Neoplasms 0.991 0.934 – 1.05 0.752 1267 12655 all phecode
189.12 Malignant neoplasm of renal pelvis Neoplasms 0.99 0.865 – 1.13 0.878 237 2347 all phecode
189.2 Cancer of bladder Neoplasms 0.998 0.949 – 1.05 0.941 1783 15224 all phecode
189.21 Malignant neoplasm of bladder Neoplasms 0.988 0.938 – 1.04 0.636 1657 14178 all phecode
189.4 Malignant neoplasm of other urinary organs Neoplasms 1.03 0.95 – 1.12 0.477 678 6586 all phecode
190 Cancer of eye Neoplasms 0.891 0.741 – 1.07 0.219 138 1374 all phecode
191
Manlignant and unknown neoplasms of brain and
Manlignant and unknown neoplasms of brain and nervous system
 Neoplasms 0.958 0.899 – 1.02 0.185 1078 10771 all phecode
191.1 Cancer of brain and nervous system Neoplasms 0.964 0.892 – 1.04 0.359 706 7052 all phecode
191.11 Cancer of brain Neoplasms 0.963 0.885 – 1.05 0.376 600 5996 all phecode
193 Thyroid cancer Neoplasms 0.951 0.888 – 1.02 0.148 945 9393 all phecode
194 Cancer of other endocrine glands Neoplasms 0.919 0.843 – 1 0.0583 579 5759 all phecode
195 Cancer, suspected or other Neoplasms 1 0.979 – 1.02 0.984 16962 26401 all phecode
195.1 Malignant neoplasm, other Neoplasms 1 0.98 – 1.02 0.913 16670 26384 all phecode
195.3 Malignant neoplasm of head, face, and neck Neoplasms 0.998 0.937 – 1.06 0.947 1103 9766 all phecode
196 Radiotherapy Neoplasms 0.993 0.951 – 1.04 0.763 2427 17006 all phecode
197 Chemotherapy Neoplasms 1.03 1 – 1.07 0.0487 4952 23797 all phecode
198 Secondary malignant neoplasm Neoplasms 1.02 0.989 – 1.05 0.202 5801 23481 all phecode
198.1 Secondary malignancy of lymph nodes Neoplasms 1.02 0.981 – 1.05 0.359 3677 21489 all phecode
198.2 Secondary malignancy of respiratory organs Neoplasms 0.994 0.932 – 1.06 0.846 1072 10334 all phecode
198.3
Secondary malignant neoplasm of digestive
Secondary malignant neoplasm of digestive systems
 Neoplasms 1.02 0.949 – 1.1 0.6 866 8538 all phecode
198.4 Secondary malignant neoplasm of liver Neoplasms 1.08 1 – 1.17 0.0446 767 7558 all phecode
198.5 Secondary malignancy of brain/spine Neoplasms 0.963 0.886 – 1.05 0.368 640 6338 all phecode
198.6 Secondary malignancy of bone Neoplasms 1.04 0.966 – 1.12 0.31 866 8307 all phecode
198.7 Secondary malignant neoplasm of skin Neoplasms 0.957 0.854 – 1.07 0.445 336 3253 all phecode
199 Neoplasm of uncertain behavior Neoplasms 0.992 0.962 – 1.02 0.597 5693 25767 all phecode
199.4 Neurofibromatosis Neoplasms 1.03 0.826 – 1.28 0.795 88 880 all phecode
200 Myeloproliferative disease Neoplasms 0.97 0.911 – 1.03 0.343 1113 11098 all phecode
200.1 Polycythemia vera Neoplasms 0.964 0.841 – 1.1 0.595 231 2310 all phecode
201 Hodgkin's disease Neoplasms 0.916 0.781 – 1.07 0.284 172 1705 all phecode
202 Cancer of other lymphoid, histiocytic tissue Neoplasms 0.986 0.935 – 1.04 0.613 1559 15571 all phecode
202.2 Non-Hodgkins lymphoma Neoplasms 0.97 0.915 – 1.03 0.304 1329 13268 all phecode
202.21 Nodular lymphoma Neoplasms 0.901 0.833 – 0.975 0.00993 693 6923 all phecode
202.22 Reticulosarcoma Neoplasms 0.981 0.836 – 1.15 0.809 170 1693 all phecode
202.24 Large cell lymphoma Neoplasms 0.963 0.815 – 1.14 0.656 160 1586 all phecode
204 Leukemia Neoplasms 0.989 0.913 – 1.07 0.782 689 6876 all phecode
204.1 Lymphoid leukemia Neoplasms 0.876 0.767 – 1 0.0522 236 2354 all phecode
204.11 Lymphoid leukemia, acute Neoplasms 0.928 0.731 – 1.18 0.54 74 734 all phecode
204.12 Lymphoid leukemia, chronic Neoplasms 0.857 0.736 – 0.998 0.0465 173 1724 all phecode
204.2 Myeloid leukemia Neoplasms 1.02 0.894 – 1.15 0.818 265 2633 all phecode
204.21 Myeloid leukemia, acute Neoplasms 0.98 0.828 – 1.16 0.813 153 1516 all phecode
204.22 Myeloid leukemia, chronic Neoplasms 1.22 0.945 – 1.59 0.126 61 610 all phecode
204.4 Multiple myeloma Neoplasms 1.04 0.902 – 1.2 0.597 217 2162 all phecode
208 Benign neoplasm of colon Neoplasms 1.01 0.991 – 1.04 0.224 10303 34953 all phecode
209 Neuroendocrine tumors Neoplasms 1.02 0.893 – 1.16 0.81 258 2580 all phecode
210 Benign neoplasm of lip, oral cavity, and pharynx Neoplasms 0.971 0.925 – 1.02 0.232 1891 18839 all phecode
211
Benign neoplasm of other parts of digestive
Benign neoplasm of other parts of digestive system
 Neoplasms 0.973 0.948 – 0.998 0.0346 7329 36606 all phecode
212
Benign neoplasm of respiratory and
Benign neoplasm of respiratory and intrathoracic organs
 Neoplasms 0.991 0.943 – 1.04 0.712 1843 18412 all phecode
213 Benign neoplasm of bone and articular cartilage Neoplasms 0.965 0.917 – 1.02 0.182 1677 15527 all phecode
214 Lipoma Neoplasms 1.03 0.978 – 1.09 0.237 1437 14132 all phecode
214.1 Lipoma of skin and subcutaneous tissue Neoplasms 1.04 0.964 – 1.11 0.341 883 8710 all phecode
215
Other benign neoplasm of connective and other
Other benign neoplasm of connective and other soft tissue
 Neoplasms 0.987 0.956 – 1.02 0.399 4528 39509 all phecode
216 Benign neoplasm of skin Neoplasms 1 0.981 – 1.02 0.822 11528 34919 all phecode
216.1 Screening for malignant neoplasms of the skin Neoplasms 0.968 0.823 – 1.14 0.698 174 1701 all phecode
217 Vascular hamartomas and non-neoplastic nevi Neoplasms 0.991 0.943 – 1.04 0.713 1786 17184 all phecode
217.1 Nevus, non-neoplastic Neoplasms 1 0.95 – 1.05 0.998 1679 16116 all phecode
218 Benign neoplasm of uterus Neoplasms 0.98 0.947 – 1.01 0.25 4301 16661 all phecode
218.1 Uterine leiomyoma Neoplasms 0.95 0.904 – 0.998 0.0423 1835 15733 all phecode
218.2 Other benign neoplasm of uterus Neoplasms 0.976 0.939 – 1.01 0.204 3403 16447 all phecode
220 Benign neoplasm of ovary Neoplasms 0.986 0.918 – 1.06 0.69 893 8783 all phecode
221 Benign neoplasm of other female genital organs Neoplasms 0.996 0.95 – 1.04 0.86 2042 14248 all phecode
222 Benign neoplasm of male genital organs Neoplasms 1 0.943 – 1.07 0.894 1133 10663 all phecode
223
Benign neoplasm of kidney and other urinary
Benign neoplasm of kidney and other urinary organs
 Neoplasms 1.02 0.965 – 1.07 0.552 1801 12657 all phecode
224 Benign neoplasm of eye Neoplasms 0.954 0.88 – 1.03 0.251 691 6752 all phecode
224.1 Benign neoplasm of eye, uveal Neoplasms 0.978 0.897 – 1.07 0.611 595 5773 all phecode
225
Benign neoplasm of brain and other parts of
Benign neoplasm of brain and other parts of nervous system
 Neoplasms 0.98 0.922 – 1.04 0.514 1209 12074 all phecode
225.1
Benign neoplasm of brain, cranial nerves
Benign neoplasm of brain, cranial nerves, meninges
 Neoplasms 0.971 0.907 – 1.04 0.403 947 9454 all phecode
225.2 Benign neoplasm of spinal cord, meninges Neoplasms 1.05 0.928 – 1.2 0.416 289 2890 all phecode
226 Benign neoplasm of thyroid glands Neoplasms 0.981 0.926 – 1.04 0.52 1329 13264 all phecode
227
Benign neoplasm of other endocrine glands and
Benign neoplasm of other endocrine glands and related structures
 Neoplasms 0.966 0.918 – 1.02 0.187 1690 16896 all phecode
227.1 Benign neoplasm of adrenal gland Neoplasms 1.08 0.98 – 1.19 0.12 467 4644 all phecode
227.2 Benign neoplasm of parathyroid gland Neoplasms 0.954 0.885 – 1.03 0.222 795 7941 all phecode
227.3
Benign neoplasm of pituitary gland and
Benign neoplasm of pituitary gland and craniopharyngeal duct (pouch)
 Neoplasms 0.916 0.828 – 1.01 0.0896 435 4350 all phecode
228 Hemangioma and lymphangioma, any site Neoplasms 1.01 0.97 – 1.06 0.524 2149 20946 all phecode
228.1 Hemangioma of skin and subcutaneous tissue Neoplasms 1.01 0.951 – 1.07 0.81 1356 13336 all phecode
229 Benign neoplasm of unspecified sites Neoplasms 0.995 0.97 – 1.02 0.709 7767 36615 all phecode
229.1 Benign neoplasm of lymph nodes Neoplasms 0.998 0.97 – 1.03 0.9 5743 34218 all phecode
240 Simple and unspecified goiter Endocrine/metabolic 0.987 0.924 – 1.05 0.694 1031 9761 all phecode
241 Nontoxic nodular goiter Endocrine/metabolic 0.985 0.946 – 1.02 0.439 2910 22227 all phecode
241.1 Nontoxic uninodular goiter Endocrine/metabolic 1 0.956 – 1.05 0.988 2265 19902 all phecode
241.2 Nontoxic multinodular goiter Endocrine/metabolic 0.967 0.912 – 1.03 0.263 1304 12479 all phecode
242 Thyrotoxicosis with or without goiter Endocrine/metabolic 0.972 0.919 – 1.03 0.322 1400 13425 all phecode
242.1 Graves' disease Endocrine/metabolic 0.978 0.892 – 1.07 0.64 515 5068 all phecode
242.2 Toxic multinodular goiter Endocrine/metabolic 1.06 0.874 – 1.28 0.562 124 1224 all phecode
242.3 Exophthalmos Endocrine/metabolic 1.08 0.955 – 1.22 0.228 292 2898 all phecode
242.31 Thyrotoxic exophthalmos Endocrine/metabolic 0.922 0.776 – 1.1 0.357 144 1432 all phecode
244 Hypothyroidism Endocrine/metabolic 0.98 0.955 – 1.01 0.127 8099 32717 all phecode
244.1 Secondary hypothyroidism Endocrine/metabolic 0.979 0.931 – 1.03 0.403 1762 17230 all phecode
244.2 Acquired hypothyroidism Endocrine/metabolic 1.03 0.966 – 1.09 0.404 1261 11982 all phecode
244.4 Hypothyroidism NOS Endocrine/metabolic 0.984 0.958 – 1.01 0.227 7542 32208 all phecode
245 Thyroiditis Endocrine/metabolic 0.988 0.917 – 1.06 0.741 832 7882 all phecode
245.2 Chronic thyroiditis Endocrine/metabolic 0.965 0.89 – 1.05 0.393 686 6517 all phecode
245.21 Chronic lymphocytic thyroiditis Endocrine/metabolic 0.957 0.883 – 1.04 0.295 679 6449 all phecode
246 Other disorders of thyroid Endocrine/metabolic 0.95 0.923 – 0.978 0.000508 6129 30240 all phecode
246.2 Thyroid cyst Endocrine/metabolic 0.886 0.718 – 1.09 0.259 101 960 all phecode
246.7 Abnormal results of function study of thyroid Endocrine/metabolic 1 0.937 – 1.08 0.889 886 8696 all phecode
249 Secondary diabetes mellitus Endocrine/metabolic 0.897 0.836 – 0.963 0.00254 1150 8340 all phecode
250 Diabetes mellitus Endocrine/metabolic 0.978 0.957 – 0.999 0.0438 13947 31815 all phecode
250.1 Type 1 diabetes Endocrine/metabolic 0.917 0.864 – 0.973 0.00446 2364 11758 all phecode
250.11 Type 1 diabetes with ketoacidosis Endocrine/metabolic 0.945 0.793 – 1.12 0.523 262 960 all phecode
250.12 Type 1 diabetes with renal manifestations Endocrine/metabolic 0.921 0.819 – 1.04 0.17 551 2686 all phecode
250.13 Type 1 diabetes with ophthalmic manifestations Endocrine/metabolic 0.936 0.838 – 1.05 0.242 784 3018 all phecode
250.14 Type 1 diabetes with neurological manifestations Endocrine/metabolic 0.982 0.875 – 1.1 0.752 638 2675 all phecode
250.15
Diabetes type 1 with peripheral circulatory
Diabetes type 1 with peripheral circulatory disorders
 Endocrine/metabolic 0.922 0.752 – 1.13 0.431 155 850 all phecode
250.2 Type 2 diabetes Endocrine/metabolic 0.961 0.937 – 0.986 0.00216 9843 29688 all phecode
250.21 Type 2 diabetes with ketoacidosis Endocrine/metabolic 0.915 0.781 – 1.07 0.271 282 1327 all phecode
250.22 Type 2 diabetes with renal manifestations Endocrine/metabolic 0.948 0.897 – 1 0.06 1941 13510 all phecode
250.23 Type 2 diabetes with ophthalmic manifestations Endocrine/metabolic 0.95 0.889 – 1.01 0.123 1643 9668 all phecode
250.24 Type 2 diabetes with neurological manifestations Endocrine/metabolic 0.973 0.926 – 1.02 0.274 2557 16502 all phecode
250.25
Diabetes type 2 with peripheral circulatory
Diabetes type 2 with peripheral circulatory disorders
 Endocrine/metabolic 1.03 0.953 – 1.12 0.425 860 6143 all phecode
250.3 Insulin pump user Endocrine/metabolic 0.946 0.905 – 0.988 0.0129 3496 20809 all phecode
250.4 Abnormal glucose Endocrine/metabolic 0.999 0.972 – 1.03 0.936 8385 30645 all phecode
250.41 Impaired fasting glucose Endocrine/metabolic 0.995 0.945 – 1.05 0.843 1870 15861 all phecode
250.42 Other abnormal glucose Endocrine/metabolic 1 0.972 – 1.03 0.992 7553 30071 all phecode
250.5 Glycosuria or Acetonuria Endocrine/metabolic 1.16 0.952 – 1.4 0.143 136 1067 all phecode
250.6 Polyneuropathy in diabetes Endocrine/metabolic 0.965 0.913 – 1.02 0.215 2132 13390 all phecode
250.7 Diabetic retinopathy Endocrine/metabolic 0.957 0.906 – 1.01 0.123 1691 10517 all phecode
251 Other disorders of pancreatic internal secretion Endocrine/metabolic 0.982 0.919 – 1.05 0.595 991 8469 all phecode
251.1 Hypoglycemia Endocrine/metabolic 0.983 0.917 – 1.05 0.625 1207 8570 all phecode
252 Disorders of parathyroid gland Endocrine/metabolic 0.987 0.945 – 1.03 0.571 2282 22119 all phecode
252.1 Hyperparathyroidism Endocrine/metabolic 0.987 0.943 – 1.03 0.578 2088 20335 all phecode
252.2 Hypoparathyroidism Endocrine/metabolic 0.999 0.91 – 1.1 0.98 508 5073 all phecode
253
Disorders of the pituitary gland and its
Disorders of the pituitary gland and its hypothalamic control
 Endocrine/metabolic 1.01 0.937 – 1.08 0.866 859 8544 all phecode
253.1 Pituitary hyperfunction Endocrine/metabolic 0.932 0.82 – 1.06 0.278 263 2621 all phecode
253.11 Acromegaly and gigantism Endocrine/metabolic 1.01 0.809 – 1.27 0.919 83 826 all phecode
253.2 Pituitary hypofunction Endocrine/metabolic 0.961 0.836 – 1.1 0.572 226 2250 all phecode
253.3 Diabetes insipidus Endocrine/metabolic 0.887 0.709 – 1.11 0.29 86 860 all phecode
253.4 Anterior pituitary disorders Endocrine/metabolic 0.888 0.733 – 1.08 0.224 121 1209 all phecode
253.7 Other disorders of neurohypophysis Endocrine/metabolic 1.21 0.995 – 1.48 0.0556 108 1080 all phecode
255 Disorders of adrenal glands Endocrine/metabolic 0.965 0.914 – 1.02 0.193 1506 14869 all phecode
255.1 Adrenal hyperfunction Endocrine/metabolic 0.965 0.867 – 1.07 0.513 373 3730 all phecode
255.11 Cushing's syndrome Endocrine/metabolic 0.987 0.846 – 1.15 0.872 183 1830 all phecode
255.12 Hyperaldosteronism Endocrine/metabolic 1.04 0.87 – 1.25 0.643 135 1350 all phecode
255.2 Adrenal hypofunction Endocrine/metabolic 0.963 0.886 – 1.05 0.381 626 6239 all phecode
255.21 Glucocorticoid deficiency Endocrine/metabolic 0.962 0.883 – 1.05 0.377 596 5941 all phecode
256 Ovarian dysfunction Endocrine/metabolic 0.961 0.903 – 1.02 0.209 1146 10513 all phecode
256.4 Polycystic ovaries Endocrine/metabolic 0.952 0.881 – 1.03 0.21 742 7128 all phecode
257 Testicular dysfunction Endocrine/metabolic 0.978 0.915 – 1.05 0.517 1015 9238 all phecode
257.1 Testicular hypofunction Endocrine/metabolic 0.99 0.924 – 1.06 0.765 983 8933 all phecode
258 Iatrogenic endocrine disorders Endocrine/metabolic 1.01 0.808 – 1.27 0.923 91 910 all phecode
258.1 Postablative ovarian failure Endocrine/metabolic 0.922 0.755 – 1.13 0.424 109 1090 all phecode
259 Other endocrine disorders Endocrine/metabolic 0.973 0.912 – 1.04 0.418 1038 10259 all phecode
260 Protein-calorie malnutrition Endocrine/metabolic 1.01 0.971 – 1.05 0.632 2880 26812 all phecode
260.1 Cachexia Endocrine/metabolic 1.03 0.912 – 1.16 0.629 292 2911 all phecode
260.2 severe protein-calorie malnutrition Endocrine/metabolic 1.03 0.978 – 1.08 0.272 1691 16847 all phecode
260.22 Nutritional marasmus Endocrine/metabolic 0.986 0.906 – 1.07 0.744 614 6140 all phecode
260.3 Adult failure to thrive Endocrine/metabolic 1 0.92 – 1.09 0.999 629 6236 all phecode
260.6 Anorexia Endocrine/metabolic 1.02 0.953 – 1.1 0.519 868 8591 all phecode
260.7 Polyphagia Endocrine/metabolic 1.03 0.795 – 1.33 0.84 65 643 all phecode
261 Vitamin deficiency Endocrine/metabolic 1.01 0.984 – 1.04 0.456 7718 35203 all phecode
261.1 Vitamin A deficiency Endocrine/metabolic 0.905 0.705 – 1.16 0.434 69 690 all phecode
261.2 Vitamin B-complex deficiencies Endocrine/metabolic 0.991 0.923 – 1.06 0.805 857 8405 all phecode
261.4 Vitamin D deficiency Endocrine/metabolic 1.01 0.988 – 1.04 0.274 7255 35225 all phecode
261.41 Rickets or osteomalacia Endocrine/metabolic 0.992 0.744 – 1.32 0.955 52 511 all phecode
262 Mineral deficiency NEC Endocrine/metabolic 0.992 0.933 – 1.05 0.79 1182 11676 all phecode
263 Other nutritional deficiency Endocrine/metabolic 0.988 0.938 – 1.04 0.638 1651 15788 all phecode
264 Lack of normal physiological development Endocrine/metabolic 0.983 0.858 – 1.13 0.809 239 2301 all phecode
264.2 Failure to thrive (childhood) Endocrine/metabolic 1.05 0.871 – 1.27 0.61 122 1220 all phecode
264.9
Lack of normal physiological development
Lack of normal physiological development, unspecified
 Endocrine/metabolic 0.836 0.66 – 1.06 0.136 81 772 all phecode
269 Proteinuria Endocrine/metabolic 1.02 0.965 – 1.07 0.547 1694 13981 all phecode
270
Disorders of protein plasma/amino-acid
Disorders of protein plasma/amino-acid transport and metabolism
 Endocrine/metabolic 0.979 0.915 – 1.05 0.544 967 9575 all phecode
270.1 Disturbances of amino-acid transport Endocrine/metabolic 0.89 0.756 – 1.05 0.16 170 1697 all phecode
270.11
Disturbances of sulphur-bearing amino-acid
Disturbances of sulphur-bearing amino-acid metabolism
 Endocrine/metabolic 0.851 0.71 – 1.02 0.0817 134 1334 all phecode
270.2 Disorders of amino-acid metabolism Endocrine/metabolic 0.801 0.651 – 0.985 0.0354 96 954 all phecode
270.3 Disorders of plasma protein metabolism Endocrine/metabolic 1.02 0.948 – 1.11 0.545 737 7303 all phecode
270.32 Paraproteinemia Endocrine/metabolic 1.01 0.912 – 1.13 0.791 384 3781 all phecode
270.33 Amyloidosis Endocrine/metabolic 1.18 0.928 – 1.49 0.181 71 695 all phecode
270.34 Alpha-1-antitrypsin deficiency Endocrine/metabolic 0.917 0.727 – 1.16 0.466 69 690 all phecode
270.38
Other specified disorders of plasma protein
Other specified disorders of plasma protein metabolism
 Endocrine/metabolic 1.06 0.935 – 1.2 0.372 299 2984 all phecode
271
Disorders of carbohydrate transport and
Disorders of carbohydrate transport and metabolism
 Endocrine/metabolic 0.993 0.955 – 1.03 0.724 2907 28132 all phecode
271.3
Intestinal disaccharidase deficiencies and
Intestinal disaccharidase deficiencies and disaccharide malabsorption
 Endocrine/metabolic 0.996 0.957 – 1.04 0.828 2827 27425 all phecode
271.9
Other disorders of carbohydrate transport and
Other disorders of carbohydrate transport and metabolism
 Endocrine/metabolic 0.826 0.677 – 1.01 0.0605 102 1007 all phecode
272 Disorders of lipoid metabolism Endocrine/metabolic 1.35 1.32 – 1.38 4.69e-163 18881 26670 all phecode
272.1 Hyperlipidemia Endocrine/metabolic 1.35 1.32 – 1.38 5.03e-164 18843 26654 all phecode
272.11 Hypercholesterolemia Endocrine/metabolic 1.48 1.43 – 1.53 1.49e-121 5928 21600 all phecode
272.12 Hyperglyceridemia Endocrine/metabolic 1.15 1.09 – 1.22 2.53e-06 1360 11837 all phecode
272.13 Mixed hyperlipidemia Endocrine/metabolic 1.4 1.34 – 1.46 6.57e-59 3538 18449 all phecode
272.9 Unspecified disorder of lipoid metabolism Endocrine/metabolic 1.17 1.04 – 1.32 0.0117 313 3011 all phecode
274 Gout and other crystal arthropathies Endocrine/metabolic 0.994 0.953 – 1.04 0.785 2524 22729 all phecode
274.1 Gout Endocrine/metabolic 0.997 0.955 – 1.04 0.896 2409 21991 all phecode
274.11 Gouty arthropathy Endocrine/metabolic 0.992 0.93 – 1.06 0.797 1082 10576 all phecode
274.2 Crystal arthropathies Endocrine/metabolic 1.03 0.887 – 1.2 0.678 195 1890 all phecode
274.21 Chondrocalcinosis Endocrine/metabolic 1.02 0.876 – 1.2 0.763 183 1772 all phecode
275 Disorders of mineral metabolism Endocrine/metabolic 0.988 0.957 – 1.02 0.451 4357 37091 all phecode
275.1 Disorders of iron metabolism Hematopoietic 0.872 0.758 – 1 0.0562 218 2180 all phecode
275.11 Hereditary hemochromatosis Hematopoietic 0.788 0.647 – 0.96 0.0179 99 990 all phecode
275.2 Disorders of copper metabolism Endocrine/metabolic 0.922 0.712 – 1.19 0.537 62 614 all phecode
275.3 Disorders of magnesium metabolism Endocrine/metabolic 1.01 0.952 – 1.08 0.68 1154 11504 all phecode
275.5 Disorders of calcium/phosphorus metabolism Endocrine/metabolic 0.979 0.944 – 1.01 0.247 3369 31544 all phecode
275.51 Hypocalcemia Endocrine/metabolic 0.923 0.86 – 0.99 0.0253 898 8969 all phecode
275.53 Disorders of phosphorus metabolism Endocrine/metabolic 0.965 0.912 – 1.02 0.217 1366 13634 all phecode
275.6 Hypercalcemia Endocrine/metabolic 1 0.948 – 1.06 0.953 1468 14183 all phecode
276
Disorders of fluid, electrolyte, and acid-base
Disorders of fluid, electrolyte, and acid-base balance
 Endocrine/metabolic 1.01 0.982 – 1.03 0.664 9238 37046 all phecode
276.1 Electrolyte imbalance Endocrine/metabolic 1 0.975 – 1.03 0.881 6352 34366 all phecode
276.11 Hyperosmolality and/or hypernatremia Endocrine/metabolic 0.989 0.906 – 1.08 0.806 550 5434 all phecode
276.12 Hyposmolality and/or hyponatremia Endocrine/metabolic 1.02 0.977 – 1.06 0.392 2514 23219 all phecode
276.13 Hyperpotassemia Endocrine/metabolic 0.981 0.944 – 1.02 0.341 2992 25216 all phecode
276.14 Hypopotassemia Endocrine/metabolic 1.02 0.973 – 1.07 0.428 2148 20909 all phecode
276.4 Acid-base balance disorder Endocrine/metabolic 0.999 0.954 – 1.05 0.975 2086 20332 all phecode
276.41 Acidosis Endocrine/metabolic 0.975 0.927 – 1.02 0.307 1788 17572 all phecode
276.42 Alkalosis Endocrine/metabolic 1.11 1.01 – 1.22 0.0272 476 4741 all phecode
276.5 Hypovolemia Endocrine/metabolic 1.01 0.981 – 1.05 0.435 4574 34527 all phecode
276.6 Fluid overload Endocrine/metabolic 0.951 0.899 – 1.01 0.0781 1384 13211 all phecode
276.8 Polydipsia Endocrine/metabolic 1.15 0.949 – 1.39 0.152 124 1240 all phecode
277 Other disorders of metabolism Endocrine/metabolic 0.985 0.953 – 1.02 0.377 4112 35070 all phecode
277.2
Other disorders of purine and pyrimidine
Other disorders of purine and pyrimidine metabolism
 Endocrine/metabolic 0.973 0.875 – 1.08 0.607 403 3991 all phecode
277.4 Disorders of bilirubin excretion Endocrine/metabolic 0.941 0.869 – 1.02 0.128 720 7161 all phecode
277.5 Other disorders of lipoid metabolism Endocrine/metabolic 0.904 0.843 – 0.969 0.0042 936 9270 all phecode
277.51 Lipoprotein disorders Endocrine/metabolic 0.891 0.825 – 0.962 0.00306 773 7668 all phecode
277.7 Dysmetabolic syndrome X Endocrine/metabolic 1.03 0.964 – 1.11 0.353 916 8359 all phecode
278 Overweight, obesity and other hyperalimentation Endocrine/metabolic 0.984 0.966 – 1 0.105 19419 27331 all phecode
278.1 Obesity Endocrine/metabolic 0.979 0.96 – 0.998 0.0343 17129 27321 all phecode
278.11 Morbid obesity Endocrine/metabolic 0.965 0.941 – 0.99 0.00648 8280 27172 all phecode
278.3 Localized adiposity Endocrine/metabolic 0.849 0.756 – 0.953 0.00541 324 3228 all phecode
278.4 Abnormal weight gain Endocrine/metabolic 1 0.959 – 1.05 0.857 2104 17411 all phecode
279 Disorders involving the immune mechanism Endocrine/metabolic 0.964 0.928 – 1 0.0661 2934 28612 all phecode
279.1 Immunity deficiency Endocrine/metabolic 0.951 0.894 – 1.01 0.107 1161 11571 all phecode
279.11 Deficiency of humoral immunity Endocrine/metabolic 0.966 0.861 – 1.08 0.558 330 3278 all phecode
279.2 Autoimmune disease NEC Endocrine/metabolic 0.962 0.891 – 1.04 0.331 754 7516 all phecode
279.7 Other immunological findings Endocrine/metabolic 0.986 0.957 – 1.02 0.382 4885 36552 all phecode
279.8
Other specified disorders involving the immune
Other specified disorders involving the immune mechanism
 Endocrine/metabolic 0.934 0.858 – 1.02 0.115 601 5988 all phecode
280 Iron deficiency anemias Hematopoietic 1.01 0.982 – 1.05 0.389 4626 30873 all phecode
280.1
Iron deficiency anemias, unspecified or not due
Iron deficiency anemias, unspecified or not due to blood loss
 Hematopoietic 1.01 0.979 – 1.04 0.496 4484 30649 all phecode
280.2
Iron deficiency anemia secondary to blood loss
Iron deficiency anemia secondary to blood loss (chronic)
 Hematopoietic 1.02 0.968 – 1.07 0.502 1771 17196 all phecode
281 Other deficiency anemia Hematopoietic 1 0.915 – 1.1 0.933 519 5120 all phecode
281.1 Megaloblastic anemia Hematopoietic 0.965 0.845 – 1.1 0.595 253 2497 all phecode
281.11 Pernicious anemia Hematopoietic 0.875 0.717 – 1.07 0.19 114 1108 all phecode
281.12 Other vitamin B12 deficiency anemia Hematopoietic 0.977 0.838 – 1.14 0.771 187 1817 all phecode
281.9 Deficiency anemias Hematopoietic 1.02 0.894 – 1.15 0.806 285 2830 all phecode
282 Hereditary hemolytic anemias Hematopoietic 0.935 0.831 – 1.05 0.27 323 3188 all phecode
282.8 Other hemoglobinopathies Hematopoietic 0.872 0.755 – 1.01 0.0609 216 2113 all phecode
282.9 Other hereditary hemolytic anemias Hematopoietic 0.987 0.848 – 1.15 0.868 192 1920 all phecode
283 Acquired hemolytic anemias Hematopoietic 0.968 0.817 – 1.15 0.71 155 1550 all phecode
283.1 Autoimmune hemolytic anemias Hematopoietic 1.08 0.835 – 1.4 0.558 64 633 all phecode
284 Aplastic anemia Hematopoietic 1.01 0.929 – 1.09 0.877 697 6943 all phecode
284.1 Pancytopenia Hematopoietic 1.02 0.934 – 1.11 0.701 612 6100 all phecode
285 Other anemias Hematopoietic 1.01 0.984 – 1.03 0.583 11794 33591 all phecode
285.1 Acute posthemorrhagic anemia Hematopoietic 1.01 0.974 – 1.05 0.588 3325 27709 all phecode
285.2 Anemia of chronic disease Hematopoietic 1 0.958 – 1.05 0.867 2055 19939 all phecode
285.21 Anemia in chronic kidney disease Hematopoietic 0.96 0.896 – 1.03 0.251 932 9106 all phecode
285.22 Anemia in neoplastic disease Hematopoietic 1 0.926 – 1.09 0.915 690 6892 all phecode
286 Coagulation defects Hematopoietic 0.988 0.955 – 1.02 0.498 3844 33384 all phecode
286.1 Congenital coagulation defects Hematopoietic 0.922 0.807 – 1.05 0.229 250 2466 all phecode
286.11 Von willebrand's disease Hematopoietic 1.01 0.794 – 1.28 0.953 83 822 all phecode
286.12
Congenital deficiency of other clotting factors
Congenital deficiency of other clotting factors (including factor VII)
 Hematopoietic 0.841 0.701 – 1.01 0.0628 126 1260 all phecode
286.2
Encounter for long-term (current) use of
Encounter for long-term (current) use of anticoagulants
 Hematopoietic 1 0.968 – 1.04 0.825 3354 25918 all phecode
286.3
Coagulation defects complicating pregnancy or
Coagulation defects complicating pregnancy or postpartum
 Hematopoietic 0.73 0.594 – 0.897 0.00272 97 962 all phecode
286.4 Acquired coagulation factor deficiency Hematopoietic 0.989 0.868 – 1.13 0.862 254 2529 all phecode
286.5
Hemorrhagic disorder due to intrinsic
Hemorrhagic disorder due to intrinsic circulating anticoagulants
 Hematopoietic 1.13 0.947 – 1.36 0.172 132 1294 all phecode
286.6 Defibrination syndrome Hematopoietic 0.982 0.942 – 1.02 0.378 2579 25377 all phecode
286.7 Other and unspecified coagulation defects Hematopoietic 0.976 0.94 – 1.01 0.219 3014 29294 all phecode
286.8 Hypercoagulable state Hematopoietic 0.934 0.869 – 1 0.0599 846 8437 all phecode
286.81 Primary hypercoagulable state Hematopoietic 0.933 0.867 – 1 0.0623 813 8111 all phecode
286.9 Abnormal coagulation profile Hematopoietic 0.986 0.928 – 1.05 0.649 1182 11487 all phecode
287 Purpura and other hemorrhagic conditions Hematopoietic 1.02 0.985 – 1.06 0.248 3288 28474 all phecode
287.1 Spontaneous ecchymoses Hematopoietic 1.09 0.943 – 1.26 0.245 211 2094 all phecode
287.3 Thrombocytopenia Hematopoietic 1.02 0.985 – 1.07 0.224 2938 26323 all phecode
287.31 Primary thrombocytopenia Hematopoietic 1.01 0.929 – 1.1 0.802 601 5994 all phecode
287.32 Secondary thrombocytopenia Hematopoietic 0.991 0.908 – 1.08 0.841 569 5686 all phecode
287.4 Qualitative platelet defects Hematopoietic 1.09 0.905 – 1.32 0.353 112 1120 all phecode
288 Diseases of white blood cells Hematopoietic 0.983 0.954 – 1.01 0.275 4886 36527 all phecode
288.1 Decreased white blood cell count Hematopoietic 0.984 0.933 – 1.04 0.56 1599 15951 all phecode
288.11 Neutropenia Hematopoietic 0.965 0.905 – 1.03 0.273 1106 11041 all phecode
288.2 Elevated white blood cell count Hematopoietic 0.972 0.94 – 1 0.0896 4082 35079 all phecode
288.3 Eosinophilia Hematopoietic 0.927 0.799 – 1.07 0.314 187 1866 all phecode
289 Other diseases of blood and blood-forming organs Hematopoietic 0.965 0.918 – 1.01 0.167 1757 17434 all phecode
289.3
Personal history of diseases of blood and
Personal history of diseases of blood and blood-forming organs
 Hematopoietic 1.02 0.949 – 1.09 0.614 918 9087 all phecode
289.4 Lymphadenitis Hematopoietic 0.987 0.954 – 1.02 0.462 3888 34715 all phecode
289.5 Diseases of spleen Hematopoietic 1.04 0.936 – 1.16 0.45 393 3913 all phecode
289.8 Polycythemia, secondary Hematopoietic 0.866 0.762 – 0.985 0.0287 255 2550 all phecode
289.9 Abnormality of red blood cells Hematopoietic 0.952 0.856 – 1.06 0.359 385 3813 all phecode
290
Delirium dementia and amnestic and other
Delirium dementia and amnestic and other cognitive disorders
 Mental Disorders 1.05 0.99 – 1.11 0.108 1318 11547 all phecode
290.1 Dementias Mental Disorders 1.14 1.04 – 1.24 0.00572 541 4910 all phecode
290.11 Alzheimer's disease Mental Disorders 1.21 1.01 – 1.43 0.0336 151 1389 all phecode
290.12 Dementia with cerebral degenerations Mental Disorders 1.06 0.849 – 1.33 0.593 88 846 all phecode
290.13 Senile dementia Mental Disorders 1.11 0.989 – 1.24 0.0774 340 3078 all phecode
290.16 Vascular dementia Mental Disorders 1.15 0.906 – 1.46 0.252 81 777 all phecode
290.2 Delirium due to conditions classified elsewhere Mental Disorders 0.996 0.923 – 1.07 0.909 750 7358 all phecode
290.3
Other persistent mental disorders due to
Other persistent mental disorders due to conditions classified elsewhere
 Mental Disorders 1.09 1.01 – 1.17 0.021 886 8618 all phecode
291
Other specified nonpsychotic and/or transient
Other specified nonpsychotic and/or transient mental disorders
 Mental Disorders 0.979 0.94 – 1.02 0.328 2550 24810 all phecode
291.1
Transient mental disorders due to conditions
Transient mental disorders due to conditions classified elsewhere
 Mental Disorders 0.986 0.848 – 1.15 0.858 175 1750 all phecode
291.4
Specific nonpsychotic mental disorders due to
Specific nonpsychotic mental disorders due to brain damage
 Mental Disorders 0.99 0.901 – 1.09 0.84 484 4807 all phecode
291.8 Alteration of consciousness Mental Disorders 0.99 0.945 – 1.04 0.685 2036 19974 all phecode
292 Neurological disorders Mental Disorders 0.988 0.96 – 1.02 0.417 5733 38553 all phecode
292.1 Aphasia/speech disturbance Mental Disorders 0.988 0.943 – 1.04 0.623 2013 19867 all phecode
292.11 Aphasia Mental Disorders 0.983 0.906 – 1.07 0.685 664 6581 all phecode
292.12 Symbolic dysfunction Mental Disorders 0.871 0.753 – 1.01 0.0616 200 1988 all phecode
292.2 Mild cognitive impairment Mental Disorders 1.08 0.974 – 1.21 0.139 389 3731 all phecode
292.3 Memory loss Mental Disorders 1.04 0.987 – 1.09 0.158 1922 18158 all phecode
292.4 Altered mental status Mental Disorders 0.962 0.922 – 1 0.0742 2454 22725 all phecode
292.5 Transient alteration of awareness Mental Disorders 0.93 0.841 – 1.03 0.153 430 4285 all phecode
292.6 Hallucinations Mental Disorders 0.89 0.775 – 1.02 0.0967 217 2147 all phecode
293 Symptoms involving head and neck Mental Disorders 0.953 0.86 – 1.06 0.364 414 4127 all phecode
293.1
Swelling, mass, or lump in head and neck
Swelling, mass, or lump in head and neck [Space-occupying lesion, intracranial NOS]
 Mental Disorders 0.99 0.959 – 1.02 0.533 4417 38609 all phecode
295 Schizophrenia and other psychotic disorders Mental Disorders 0.932 0.868 – 1 0.0559 885 8229 all phecode
295.1 Schizophrenia Mental Disorders 0.941 0.783 – 1.13 0.514 138 1339 all phecode
295.2 Paranoid disorders Mental Disorders 0.844 0.694 – 1.03 0.0887 118 1079 all phecode
295.3 Psychosis Mental Disorders 0.945 0.873 – 1.02 0.161 716 6694 all phecode
296 Mood disorders Mental Disorders 1 0.981 – 1.02 0.843 15356 20858 all phecode
296.1 Bipolar Mental Disorders 0.999 0.942 – 1.06 0.986 1301 11264 all phecode
296.2 Depression Mental Disorders 1 0.981 – 1.03 0.779 14833 20856 all phecode
296.22 Major depressive disorder Mental Disorders 0.999 0.977 – 1.02 0.918 13850 20853 all phecode
297 Suicidal ideation or attempt Mental Disorders 0.957 0.893 – 1.02 0.204 985 9050 all phecode
297.1 Suicidal ideation Mental Disorders 0.971 0.899 – 1.05 0.447 788 7310 all phecode
297.2 Suicide or self-inflicted injury Mental Disorders 0.955 0.843 – 1.08 0.475 285 2654 all phecode
300 Anxiety disorders Mental Disorders 1.01 0.984 – 1.03 0.632 15419 20850 all phecode
300.1 Anxiety disorder Mental Disorders 1.01 0.984 – 1.03 0.609 14517 20855 all phecode
300.11 Generalized anxiety disorder Mental Disorders 0.992 0.962 – 1.02 0.63 5546 20512 all phecode
300.12 Agorophobia, social phobia, and panic disorder Mental Disorders 0.995 0.937 – 1.06 0.873 1360 11377 all phecode
300.13 Phobia Mental Disorders 0.975 0.911 – 1.04 0.451 1051 9542 all phecode
300.3 Obsessive-compulsive disorders Mental Disorders 0.876 0.777 – 0.988 0.0313 328 3018 all phecode
300.4 Dysthymic disorder Mental Disorders 1.01 0.966 – 1.06 0.647 2420 16552 all phecode
300.8 Acute reaction to stress Mental Disorders 0.972 0.885 – 1.07 0.559 504 4825 all phecode
300.9 Posttraumatic stress disorder Mental Disorders 1.01 0.937 – 1.09 0.807 843 7909 all phecode
301 Personality disorders Mental Disorders 0.996 0.902 – 1.1 0.937 477 4539 all phecode
301.2 Antisocial/borderline personality disorder Mental Disorders 1.01 0.878 – 1.15 0.938 254 2393 all phecode
302 Sexual and gender identity disorders Mental Disorders 0.971 0.934 – 1.01 0.125 3700 13808 all phecode
302.1 Decreased libido Mental Disorders 0.874 0.789 – 0.967 0.00914 447 4331 all phecode
303 Psychogenic and somatoform disorders Mental Disorders 0.999 0.971 – 1.03 0.951 6808 20043 all phecode
303.1 Dissociative disorder Mental Disorders 0.949 0.804 – 1.12 0.541 161 1573 all phecode
303.3 Psychogenic disorder Mental Disorders 0.998 0.969 – 1.03 0.875 6487 19888 all phecode
303.31
Gastrointestinal malfunction arising from
Gastrointestinal malfunction arising from mental factors
 Mental Disorders 0.924 0.837 – 1.02 0.114 471 4623 all phecode
303.4 Somatoform disorder Mental Disorders 0.992 0.932 – 1.06 0.797 1177 11180 all phecode
304 Adjustment reaction Mental Disorders 0.993 0.958 – 1.03 0.703 3888 20475 all phecode
305.2 Eating disorder Mental Disorders 0.936 0.872 – 1 0.0655 901 8329 all phecode
306 Other mental disorder Mental Disorders 0.974 0.926 – 1.02 0.302 1815 14133 all phecode
306.1 Mental disorders durring/after pregnancy Mental Disorders 1.05 0.957 – 1.15 0.308 587 3527 all phecode
306.9 Tension headache Mental Disorders 0.944 0.873 – 1.02 0.139 753 7277 all phecode
312 Conduct disorders Mental Disorders 1.03 0.9 – 1.17 0.695 254 2501 all phecode
312.3 Impulse control disorder Mental Disorders 0.974 0.755 – 1.26 0.84 74 736 all phecode
313 Pervasive developmental disorders Mental Disorders 1.01 0.959 – 1.07 0.654 1571 14633 all phecode
313.1 Attention deficit hyperactivity disorder Mental Disorders 1.01 0.952 – 1.07 0.786 1392 13190 all phecode
313.2 Tics and stuttering Mental Disorders 1.03 0.817 – 1.3 0.802 77 770 all phecode
313.3 Autism Mental Disorders 0.993 0.769 – 1.28 0.958 64 621 all phecode
315 Develomental delays and disorders Mental Disorders 1.02 0.939 – 1.1 0.684 684 6788 all phecode
315.1 Learning disorder Mental Disorders 1.02 0.814 – 1.29 0.838 87 860 all phecode
315.2 Speech and language disorder Mental Disorders 1 0.879 – 1.14 0.98 254 2539 all phecode
316 Substance addiction and disorders Mental Disorders 1 0.969 – 1.04 0.832 3682 32680 all phecode
316.1 Polyneuropathy due to drugs Mental Disorders 1.02 0.937 – 1.11 0.654 634 6331 all phecode
317 Alcohol-related disorders Mental Disorders 1.01 0.97 – 1.05 0.589 2525 22920 all phecode
317.1 Alcoholism Mental Disorders 1.01 0.961 – 1.06 0.754 1986 19339 all phecode
317.11 Alcoholic liver damage Mental Disorders 0.921 0.83 – 1.02 0.121 408 4080 all phecode
318 Tobacco use disorder Mental Disorders 1.01 0.986 – 1.03 0.409 8622 34842 all phecode
320 Meningitis Neurological 1.09 0.982 – 1.21 0.106 382 3820 all phecode
323 Encephalitis Neurological 1.05 0.898 – 1.22 0.558 181 1809 all phecode
323.8 Encephalitis, non-infectious Neurological 0.992 0.841 – 1.17 0.92 153 1527 all phecode
324 Other CNS infection and poliomyelitis Neurological 1.01 0.899 – 1.14 0.815 288 2880 all phecode
325
Phlebitis and thrombophlebitis of intracranial
Phlebitis and thrombophlebitis of intracranial venous sinuses
 Neurological 0.874 0.661 – 1.16 0.343 53 530 all phecode
327 Sleep disorders Neurological 0.989 0.969 – 1.01 0.27 14941 31602 all phecode
327.1 Hypersomnia Neurological 1.01 0.968 – 1.06 0.556 2061 19110 all phecode
327.3 Sleep apnea Neurological 0.991 0.969 – 1.01 0.443 10909 31304 all phecode
327.31 Central/nonobstroctive sleep apnea Neurological 0.938 0.853 – 1.03 0.185 492 4784 all phecode
327.32 Obstructive sleep apnea Neurological 0.99 0.965 – 1.01 0.408 8744 30530 all phecode
327.4 Insomnia Neurological 0.996 0.967 – 1.03 0.773 5524 30960 all phecode
327.41 Organic or persistent insomnia Neurological 0.968 0.913 – 1.03 0.289 1265 12120 all phecode
327.5 Parasomnia Neurological 0.947 0.868 – 1.03 0.212 604 5913 all phecode
327.6 Circadian rhythm sleep disorder Neurological 0.835 0.733 – 0.952 0.00688 274 2666 all phecode
327.7 Sleep related movement disorders Neurological 0.934 0.889 – 0.981 0.00665 1786 17323 all phecode
327.71 Restless legs syndrome Neurological 0.93 0.882 – 0.98 0.00686 1570 15360 all phecode
327.72 Sleep related leg cramps Neurological 1.06 0.852 – 1.33 0.591 83 822 all phecode
331 Other cerebral degenerations Neurological 1.03 0.956 – 1.12 0.409 717 7024 all phecode
331.1 Hydrocephalus Neurological 0.976 0.862 – 1.11 0.704 284 2836 all phecode
331.9 Cerebral degeneration, unspecified Neurological 1.05 0.946 – 1.16 0.362 419 4026 all phecode
332 Parkinson's disease Neurological 0.918 0.829 – 1.02 0.0995 415 4128 all phecode
333
Extrapyramidal disease and abnormal movement
Extrapyramidal disease and abnormal movement disorders
 Neurological 0.969 0.931 – 1.01 0.112 2868 26583 all phecode
333.1 Essential tremor Neurological 0.983 0.91 – 1.06 0.673 725 7163 all phecode
333.2 Myoclonus Neurological 1.06 0.901 – 1.25 0.471 159 1590 all phecode
333.4 Torsion dystonia Neurological 1.03 0.915 – 1.15 0.664 352 3504 all phecode
333.8 Other degenerative diseases of the basal ganglia Neurological 1.04 0.832 – 1.3 0.727 89 890 all phecode
334 Degenerative disease of the spinal cord Neurological 0.948 0.889 – 1.01 0.102 1058 10562 all phecode
334.1 Spinocerebellar disease Neurological 0.811 0.638 – 1.03 0.0857 79 790 all phecode
334.2 Anterior horn cell disease Neurological 0.861 0.709 – 1.05 0.13 110 1080 all phecode
334.21 Amyotrophic Lateral Sclerosis Neurological 0.807 0.636 – 1.02 0.076 71 693 all phecode
335 Multiple sclerosis Neurological 0.937 0.844 – 1.04 0.23 396 3951 all phecode
337 Disorders of the autonomic nervous system Neurological 0.916 0.852 – 0.985 0.0186 808 7413 all phecode
337.1 Peripheral autonomic neuropathy Neurological 0.904 0.811 – 1.01 0.071 370 3164 all phecode
338 Pain Neurological 1.01 0.987 – 1.02 0.57 20346 26417 all phecode
338.1 Acute pain Neurological 1 0.98 – 1.02 0.984 15582 26313 all phecode
338.2 Chronic pain Neurological 1 0.98 – 1.03 0.805 10994 26368 all phecode
339 Other headache syndromes Neurological 0.989 0.965 – 1.01 0.366 9242 34658 all phecode
340 Migraine Neurological 0.997 0.969 – 1.02 0.807 6708 30587 all phecode
340.1 Migrain with aura Neurological 1.02 0.979 – 1.05 0.417 3624 23684 all phecode
341
Other demyelinating diseases of central nervous
Other demyelinating diseases of central nervous system
 Neurological 0.88 0.734 – 1.06 0.167 133 1330 all phecode
342 Hemiplegia Neurological 0.919 0.835 – 1.01 0.0829 464 4607 all phecode
343 Infantile cerebral palsy Neurological 1.14 0.908 – 1.42 0.266 85 847 all phecode
344 Other paralytic syndromes Neurological 1.06 0.975 – 1.15 0.174 682 6808 all phecode
345 Epilepsy, recurrent seizures, convulsions Neurological 0.951 0.913 – 0.992 0.0182 2553 25307 all phecode
345.1 Epilepsy Neurological 0.899 0.833 – 0.97 0.0059 747 7465 all phecode
345.11 Generalized convulsive epilepsy Neurological 0.941 0.821 – 1.08 0.384 233 2330 all phecode
345.12 Partial epilepsy Neurological 0.924 0.844 – 1.01 0.0871 534 5335 all phecode
345.3 Convulsions Neurological 0.941 0.902 – 0.982 0.00548 2396 23796 all phecode
346
Abnormal findings on study of brain and/or
Abnormal findings on study of brain and/or nervous system
 Neurological 0.976 0.838 – 1.14 0.752 183 1824 all phecode
346.1
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of skull and head
 Neurological 0.998 0.946 – 1.05 0.956 1472 14587 all phecode
346.2
Nonspecific abnormal results of function study
Nonspecific abnormal results of function study of brain and central nervous system
 Neurological 1.03 0.849 – 1.24 0.794 120 1181 all phecode
346.3
Nonspecific abnormal findings in cerebrospinal
Nonspecific abnormal findings in cerebrospinal fluid
 Neurological 0.811 0.671 – 0.981 0.0307 110 1100 all phecode
347 Cataplexy and narcolepsy Neurological 0.952 0.777 – 1.17 0.634 101 1010 all phecode
348 Other conditions of brain Neurological 0.969 0.922 – 1.02 0.206 1793 17894 all phecode
348.2 Cerebral edema and compression of brain Neurological 0.94 0.877 – 1.01 0.077 905 9034 all phecode
348.4 Cerebral cysts Neurological 0.925 0.805 – 1.06 0.274 229 2290 all phecode
348.7 Coma Neurological 1.11 0.971 – 1.28 0.123 229 2275 all phecode
348.8 Encephalopathy, not elsewhere classified Neurological 1.01 0.942 – 1.08 0.769 853 8479 all phecode
348.9 Other conditions of brain, NOS Neurological 0.972 0.931 – 1.02 0.203 2341 23287 all phecode
349
Other and unspecified disorders of the nervous
Other and unspecified disorders of the nervous system
 Neurological 1 0.938 – 1.08 0.894 941 9385 all phecode
350 Abnormal movement Neurological 0.993 0.967 – 1.02 0.596 6706 38762 all phecode
350.1 Abnormal involuntary movements Neurological 0.997 0.961 – 1.03 0.864 3273 30524 all phecode
350.2 Abnormality of gait Neurological 0.98 0.947 – 1.01 0.239 3920 30520 all phecode
350.3 Lack of coordination Neurological 0.977 0.916 – 1.04 0.492 1062 10554 all phecode
350.5 Abnormal reflex Neurological 0.892 0.771 – 1.03 0.126 200 1988 all phecode
350.6 Disturbances of sensation of smell and taste Neurological 0.988 0.904 – 1.08 0.796 558 5576 all phecode
351 Other peripheral nerve disorders Neurological 1.01 0.985 – 1.04 0.404 7401 34460 all phecode
352 Disorders of other cranial nerves Neurological 0.966 0.918 – 1.02 0.177 1714 17106 all phecode
352.1 Trigeminal nerve disorders [CN5] Neurological 0.902 0.823 – 0.989 0.0285 535 5344 all phecode
352.2 Facial nerve disorders [CN7] Neurological 0.97 0.9 – 1.05 0.431 783 7826 all phecode
353 Nerve root and plexus disorders Neurological 0.981 0.949 – 1.01 0.247 4256 33369 all phecode
353.1 Nerve plexus lesions Neurological 0.962 0.865 – 1.07 0.473 390 3900 all phecode
353.2 Nerve root lesions Neurological 0.893 0.748 – 1.07 0.209 130 1287 all phecode
355 Complex regional/central pain syndrome Neurological 0.875 0.798 – 0.958 0.00398 531 5295 all phecode
355.1 Chronic pain syndrome Neurological 0.993 0.923 – 1.07 0.844 843 8386 all phecode
356 Hereditary and idiopathic peripheral neuropathy Neurological 0.981 0.939 – 1.03 0.398 2335 20731 all phecode
357 Inflammatory and toxic neuropathy Neurological 1.01 0.971 – 1.04 0.697 3472 29956 all phecode
358 Myoneural disorders Neurological 0.985 0.926 – 1.05 0.64 1147 11391 all phecode
358.1 Myasthenia gravis Neurological 1.02 0.825 – 1.27 0.844 109 1082 all phecode
359 Muscular dystrophies and other myopathies Neurological 0.934 0.878 – 0.994 0.0308 1134 11274 all phecode
359.1 Muscular dystrophies Neurological 0.837 0.643 – 1.09 0.187 64 632 all phecode
359.2 Myopathy Neurological 0.936 0.879 – 0.997 0.039 1092 10843 all phecode
360 Disorders of the globe Sense Organs 0.998 0.832 – 1.2 0.986 131 1276 all phecode
360.2 Progressive myopia Sense Organs 0.956 0.74 – 1.23 0.728 65 640 all phecode
361 Retinal detachments and defects Sense Organs 0.943 0.873 – 1.02 0.133 733 7131 all phecode
361.1 Retinal detachment with retinal defect Sense Organs 0.952 0.847 – 1.07 0.411 302 2962 all phecode
362 Other retinal disorders Sense Organs 1.02 0.981 – 1.06 0.354 3569 22997 all phecode
362.2
Degeneration of macula and posterior pole of
Degeneration of macula and posterior pole of retina
 Sense Organs 1.04 0.996 – 1.09 0.0745 2172 15483 all phecode
362.21 Macular degeneration, dry Sense Organs 0.998 0.901 – 1.1 0.966 419 3438 all phecode
362.22 Macular degeneration, wet Sense Organs 0.953 0.803 – 1.13 0.584 148 1184 all phecode
362.23 Cystoid macular degeneration of retina Sense Organs 1.05 0.943 – 1.16 0.388 408 3839 all phecode
362.26 Macular puckering of retina Sense Organs 1.06 0.99 – 1.13 0.0937 976 8610 all phecode
362.27 Drusen (degenerative) of retina Sense Organs 1.06 0.962 – 1.16 0.247 488 4558 all phecode
362.29 Macular degeneration (senile) of retina NOS Sense Organs 1.03 0.984 – 1.09 0.181 1883 13955 all phecode
362.3 Other nondiabetic retinopathy Sense Organs 0.967 0.904 – 1.03 0.33 976 8527 all phecode
362.31 Separation of retinal layers Sense Organs 0.969 0.876 – 1.07 0.55 413 4056 all phecode
362.4 Retinal vascular changes and abnomalities Sense Organs 0.999 0.921 – 1.08 0.982 662 5933 all phecode
362.6 Peripheral retinal degenerations Sense Organs 1.01 0.911 – 1.12 0.844 392 3787 all phecode
362.7 Hereditary retinal dystrophies Sense Organs 0.972 0.843 – 1.12 0.693 215 2103 all phecode
362.8 Retinal hemorrhage/ischemia Sense Organs 0.887 0.777 – 1.01 0.0738 241 2368 all phecode
362.9 Retinal edema Sense Organs 0.902 0.803 – 1.01 0.0853 324 2936 all phecode
363
Chorioretinal inflammations, scars, and other
Chorioretinal inflammations, scars, and other disorders of choroid
 Sense Organs 0.978 0.89 – 1.08 0.647 492 4746 all phecode
363.3 Chorioretinal scars Sense Organs 0.998 0.89 – 1.12 0.974 332 3184 all phecode
364 Corneal opacity and other disorders of cornea Sense Organs 1.02 0.959 – 1.09 0.507 1132 10772 all phecode
364.1 Corneal opacity Sense Organs 0.903 0.813 – 1 0.0585 394 3846 all phecode
364.2 Corneal edema Sense Organs 0.867 0.715 – 1.05 0.145 123 1208 all phecode
364.4 Corneal degenerations Sense Organs 0.934 0.841 – 1.04 0.199 402 3962 all phecode
364.41 Keratoconus Sense Organs 1.03 0.808 – 1.32 0.797 75 739 all phecode
364.5 Corneal dystrophy Sense Organs 1.15 1.04 – 1.26 0.00438 502 4682 all phecode
364.51 Fuchs' dystrophy Sense Organs 1.07 0.938 – 1.21 0.328 266 2521 all phecode
364.9 Cornea replaced by transplant Sense Organs 1.19 0.957 – 1.48 0.118 91 885 all phecode
365 Glaucoma Sense Organs 0.998 0.958 – 1.04 0.933 2672 21326 all phecode
365.1 Open-angle glaucoma Sense Organs 0.976 0.902 – 1.06 0.546 705 6491 all phecode
365.11 Primary open angle glaucoma Sense Organs 1.03 0.927 – 1.14 0.581 403 3681 all phecode
365.2 Primary angle-closure glaucoma Sense Organs 1.04 0.913 – 1.19 0.533 251 2370 all phecode
366 Cataract Sense Organs 1.01 0.985 – 1.04 0.401 8611 28043 all phecode
366.1 Nonsenile Cataract Sense Organs 0.997 0.859 – 1.16 0.97 207 1979 all phecode
366.2 Senile cataract Sense Organs 1.02 0.989 – 1.05 0.21 5480 24980 all phecode
367
Disorders of refraction and accommodation
Disorders of refraction and accommodation; blindness and low vision
 Sense Organs 1.01 0.982 – 1.03 0.624 8967 37779 all phecode
367.1 Myopia Sense Organs 1.01 0.978 – 1.04 0.591 5014 34677 all phecode
367.2 Astigmatism Sense Organs 1.01 0.975 – 1.04 0.617 4161 32463 all phecode
367.8 Hypermetropia Sense Organs 1.03 0.984 – 1.08 0.194 2039 18599 all phecode
367.9 Blindness and low vision Sense Organs 0.939 0.885 – 0.996 0.0359 1277 12356 all phecode
368 Visual disturbances Sense Organs 1.02 0.995 – 1.05 0.101 5715 39599 all phecode
368.1 Amblyopia Sense Organs 1.06 0.977 – 1.15 0.16 651 6479 all phecode
368.2 Diplopia and disorders of binocular vision Sense Organs 0.931 0.874 – 0.993 0.0292 1087 10786 all phecode
368.3 Anisometropia Sense Organs 0.887 0.772 – 1.02 0.0903 219 2168 all phecode
368.4 Visual field defects Sense Organs 0.964 0.906 – 1.03 0.248 1132 11173 all phecode
368.9 Subjective visual disturbances Sense Organs 0.982 0.921 – 1.05 0.58 1070 10620 all phecode
368.91 Psychophysical visual disturbances Sense Organs 0.9 0.746 – 1.08 0.267 120 1171 all phecode
369 Infection of the eye Sense Organs 1.01 0.968 – 1.04 0.783 3185 28240 all phecode
369.2 Eye infection, viral Sense Organs 0.989 0.899 – 1.09 0.828 502 4954 all phecode
369.5 Conjunctivitis, infectious Sense Organs 1.01 0.966 – 1.05 0.784 2716 24970 all phecode
370 Keratitis Sense Organs 0.984 0.929 – 1.04 0.582 1365 13169 all phecode
370.1 Corneal ulcer Sense Organs 1.1 0.95 – 1.26 0.207 223 2194 all phecode
370.2 Superficial keratitis Sense Organs 0.953 0.87 – 1.04 0.295 546 5393 all phecode
370.3 Keratoconjunctivitis Sense Organs 0.943 0.869 – 1.02 0.16 649 6263 all phecode
370.31 Keratoconjunctivitis sicca Sense Organs 1.01 0.861 – 1.18 0.936 179 1677 all phecode
371 Inflammation of the eye Sense Organs 0.997 0.965 – 1.03 0.845 4414 32310 all phecode
371.1 Uveitis, noninfectious or NOS Sense Organs 0.97 0.887 – 1.06 0.509 541 5278 all phecode
371.2 Conjunctivitis, noninfectious Sense Organs 0.974 0.908 – 1.05 0.471 906 8939 all phecode
371.21 Allergic conjunctivitis Sense Organs 0.992 0.918 – 1.07 0.839 756 7515 all phecode
371.3 Inflammation of eyelids Sense Organs 0.997 0.961 – 1.03 0.87 3398 26983 all phecode
371.33 Noninfectious dermatoses of eyelid Sense Organs 0.981 0.816 – 1.18 0.836 133 1291 all phecode
372 Disorders of conjunctiva Sense Organs 1.06 0.999 – 1.14 0.0544 1118 10728 all phecode
374 Other disorders of eyelids Sense Organs 1.01 0.973 – 1.05 0.536 2940 24188 all phecode
374.1 Ectropion or entropion Sense Organs 0.938 0.849 – 1.04 0.212 431 4084 all phecode
374.2 Lagophthalmos Sense Organs 0.892 0.778 – 1.02 0.103 235 2335 all phecode
374.3 Ptosis of eyelid Sense Organs 0.963 0.904 – 1.02 0.233 1102 10734 all phecode
374.6 Dermatochalasis Sense Organs 1.01 0.943 – 1.08 0.836 1040 9720 all phecode
375 Disorders of lacrimal system Sense Organs 0.959 0.925 – 0.994 0.0213 3694 26045 all phecode
375.1 Dry eyes Sense Organs 0.984 0.95 – 1.02 0.347 4040 26751 all phecode
375.2 Epiphora Sense Organs 0.86 0.779 – 0.951 0.00312 442 4354 all phecode
376 Disorders of the orbit Sense Organs 1.03 0.917 – 1.15 0.657 352 3508 all phecode
377 Disorders of optic nerve and visual pathways Sense Organs 1.01 0.946 – 1.09 0.687 913 9021 all phecode
377.1 Optic atrophy Sense Organs 0.972 0.859 – 1.1 0.653 283 2793 all phecode
377.3 Optic neuritis/neuropathy Sense Organs 1.03 0.942 – 1.12 0.552 585 5775 all phecode
378
Strabismus and other disorders of binocular eye
Strabismus and other disorders of binocular eye movements
 Sense Organs 0.974 0.919 – 1.03 0.383 1275 12460 all phecode
378.1 Strabismus (not specified as paralytic) Sense Organs 0.969 0.902 – 1.04 0.397 828 8130 all phecode
378.2 Nystagmus and other irregular eye movements Sense Organs 0.998 0.853 – 1.17 0.98 170 1686 all phecode
378.5 Paralytic strabismus Sense Organs 0.916 0.819 – 1.02 0.124 349 3437 all phecode
379 Other disorders of eye Sense Organs 1.01 0.983 – 1.05 0.368 5046 29999 all phecode
379.1 Scleritis and episcleritis Sense Organs 0.887 0.753 – 1.05 0.155 176 1743 all phecode
379.2 Disorders of vitreous body Sense Organs 1.03 0.993 – 1.07 0.111 3634 23186 all phecode
379.3 Aphakia and other disorders of lens Sense Organs 0.849 0.71 – 1.02 0.0734 135 1258 all phecode
379.4 Anomalies of pupillary function Sense Organs 0.998 0.883 – 1.13 0.978 287 2833 all phecode
379.5 Disorders of iris and ciliary body Sense Organs 0.96 0.849 – 1.09 0.516 304 2948 all phecode
379.51 Pigmentary iris degeneration Sense Organs 1.15 0.901 – 1.46 0.265 77 731 all phecode
379.9 Pain, swelling or discharge of eye Sense Organs 0.96 0.902 – 1.02 0.193 1129 11130 all phecode
380 Disorders of external ear Sense Organs 1.02 0.972 – 1.06 0.468 2242 20393 all phecode
380.1 Otitis externa Sense Organs 0.99 0.937 – 1.05 0.723 1469 14580 all phecode
380.4 Impacted cerumen Sense Organs 1.03 0.985 – 1.07 0.212 2648 23557 all phecode
381 Otitis media and Eustachian tube disorders Sense Organs 0.986 0.954 – 1.02 0.398 4255 36417 all phecode
381.1 Otitis media Sense Organs 0.987 0.95 – 1.02 0.491 3079 29813 all phecode
381.11 Suppurative and unspecified otitis media Sense Organs 0.99 0.95 – 1.03 0.632 2610 25602 all phecode
381.2 Eustachian tube disorders Sense Organs 0.971 0.924 – 1.02 0.242 1816 17827 all phecode
381.3 Mastoiditis & related conditions Sense Organs 1.05 0.885 – 1.24 0.577 153 1530 all phecode
381.9 Otorrhea Sense Organs 0.991 0.889 – 1.11 0.872 372 3713 all phecode
382 Otalgia Sense Organs 0.999 0.951 – 1.05 0.961 1884 18673 all phecode
383 Otosclerosis Sense Organs 0.966 0.803 – 1.16 0.709 124 1240 all phecode
384 Other disorders of tympanic membrane Sense Organs 0.991 0.904 – 1.09 0.839 516 5156 all phecode
384.1 Myringitis Sense Organs 1.06 0.785 – 1.42 0.716 51 502 all phecode
384.4 Perforation of tympanic membrane Sense Organs 0.972 0.877 – 1.08 0.595 403 4029 all phecode
385 Other disorders of middle ear and mastoid Sense Organs 1.01 0.909 – 1.11 0.908 432 4320 all phecode
385.3 Cholesteatoma Sense Organs 0.99 0.873 – 1.12 0.876 277 2770 all phecode
385.5
Tympanosclerosis and middle ear disease related
Tympanosclerosis and middle ear disease related to otitis media
 Sense Organs 1.01 0.837 – 1.22 0.902 118 1180 all phecode
386
Vertiginous syndromes and other disorders of
Vertiginous syndromes and other disorders of vestibular system
 Sense Organs 1 0.956 – 1.05 0.875 1882 18186 all phecode
386.1 Meniere's disease Sense Organs 0.983 0.874 – 1.11 0.777 319 3156 all phecode
386.2 Peripheral or central vertigo Sense Organs 1.01 0.963 – 1.07 0.582 1586 15423 all phecode
386.21 Central origin vertigo Sense Organs 1.03 0.967 – 1.09 0.384 1208 11844 all phecode
386.3 Labyrinthitis Sense Organs 1.01 0.96 – 1.07 0.62 1482 14530 all phecode
386.9
Dizziness and giddiness (Light-headedness and
Dizziness and giddiness (Light-headedness and vertigo)
 Sense Organs 1.02 0.993 – 1.05 0.16 6933 38286 all phecode
388 Other disorders of ear Sense Organs 1.01 0.94 – 1.08 0.879 960 9501 all phecode
389 Hearing loss Sense Organs 1.01 0.98 – 1.03 0.69 8182 38069 all phecode
389.1 Sensorineural hearing loss Sense Organs 1.01 0.972 – 1.04 0.746 4107 29258 all phecode
389.2 Conductive hearing loss Sense Organs 0.947 0.884 – 1.02 0.125 905 9042 all phecode
389.3 Degenerative and vascular disorders of ear Sense Organs 0.957 0.82 – 1.12 0.572 192 1808 all phecode
389.4 Tinnitus Sense Organs 1.03 0.987 – 1.08 0.166 2291 22130 all phecode
389.5 Disorders of acoustic nerve Sense Organs 1.03 0.854 – 1.23 0.778 124 1229 all phecode
394 Rheumatic disease of the heart valves Circulatory System 1 0.949 – 1.06 0.919 1458 13732 all phecode
394.1 Mitral valve stenosis and aortic valve stenosis Circulatory System 1 0.899 – 1.12 0.934 350 3415 all phecode
394.2 Mitral valve disease Circulatory System 1.03 0.932 – 1.13 0.575 462 4560 all phecode
394.3 Aortic valve disease Circulatory System 1.05 0.893 – 1.22 0.579 176 1691 all phecode
394.4 Acute rheumatic heart disease Circulatory System 0.747 0.571 – 0.978 0.0339 55 546 all phecode
394.7 Disease of tricuspid valve Circulatory System 1.03 0.942 – 1.12 0.543 587 5739 all phecode
395 Heart valve disorders Circulatory System 1.06 1.02 – 1.1 0.00109 3976 28748 all phecode
395.1 Nonrheumatic mitral valve disorders Circulatory System 1.05 1 – 1.1 0.044 2175 20441 all phecode
395.2 Nonrheumatic aortic valve disorders Circulatory System 1.09 1.04 – 1.14 0.000549 2060 17194 all phecode
395.3 Nonrheumatic tricuspid valve disorders Circulatory System 1.05 0.951 – 1.15 0.354 493 4864 all phecode
395.4 Nonrheumatic pulmonary valve disorders Circulatory System 0.94 0.767 – 1.15 0.549 108 1080 all phecode
395.6 Heart valve replaced Circulatory System 1.06 0.995 – 1.13 0.071 1177 10833 all phecode
396 Abnormal heart sounds Circulatory System 1.05 1.01 – 1.08 0.00494 4718 34395 all phecode
401 Hypertension Circulatory System 1.01 0.984 – 1.03 0.628 23317 23367 all phecode
401.1 Essential hypertension Circulatory System 1.01 0.985 – 1.03 0.589 23158 23364 all phecode
401.2 Hypertensive heart and/or renal disease Circulatory System 0.98 0.942 – 1.02 0.317 3503 14616 all phecode
401.21 Hypertensive heart disease Circulatory System 1.07 0.998 – 1.15 0.0556 893 6607 all phecode
401.22 Hypertensive chronic kidney disease Circulatory System 0.957 0.916 – 1 0.0551 2584 13072 all phecode
401.3 Other hypertensive complications Circulatory System 1.03 0.982 – 1.07 0.253 2679 15833 all phecode
411 Ischemic Heart Disease Circulatory System 1.08 1.06 – 1.11 8.63e-10 8807 30299 all phecode
411.1 Unstable angina (intermediate coronary syndrome) Circulatory System 1.2 1.12 – 1.29 3.27e-07 937 8574 all phecode
411.2 Myocardial infarction Circulatory System 1.09 1.05 – 1.13 9.42e-06 3594 21716 all phecode
411.3 Angina pectoris Circulatory System 1.09 1.04 – 1.14 0.000107 2485 18304 all phecode
411.4 Coronary atherosclerosis Circulatory System 1.1 1.07 – 1.13 1.01e-10 7555 27492 all phecode
411.41 Aneurysm and dissection of heart Circulatory System 1.04 0.871 – 1.24 0.678 156 1529 all phecode
411.8
Other chronic ischemic heart disease
Other chronic ischemic heart disease, unspecified
 Circulatory System 1.1 1.07 – 1.13 1.92e-10 6331 25741 all phecode
411.9
Other acute and subacute forms of ischemic
Other acute and subacute forms of ischemic heart disease
 Circulatory System 1.01 0.915 – 1.12 0.821 442 4211 all phecode
414 Other forms of chronic heart disease Circulatory System 1.11 1.07 – 1.16 1.16e-07 3101 22616 all phecode
414.2 ASCVD Circulatory System 1.13 1.04 – 1.22 0.00287 718 6816 all phecode
415 Pulmonary heart disease Circulatory System 0.991 0.955 – 1.03 0.61 3366 30208 all phecode
415.1 Acute pulmonary heart disease Circulatory System 0.989 0.943 – 1.04 0.651 1912 19014 all phecode
415.11 Pulmonary embolism and infarction, acute Circulatory System 0.987 0.941 – 1.04 0.585 1906 18953 all phecode
415.2 Chronic pulmonary heart disease Circulatory System 0.994 0.946 – 1.04 0.815 1808 17605 all phecode
415.21 Primary pulmonary hypertension Circulatory System 0.988 0.913 – 1.07 0.773 706 7032 all phecode
416 Cardiomegaly Circulatory System 0.947 0.893 – 1.01 0.0746 1254 12372 all phecode
418 Nonspecific chest pain Circulatory System 1.02 0.995 – 1.04 0.144 12650 33952 all phecode
418.1 Precordial pain Circulatory System 1.06 1 – 1.12 0.0442 1471 13782 all phecode
420 Carditis Circulatory System 1.04 0.989 – 1.1 0.12 1588 15680 all phecode
420.1 Myocarditis Circulatory System 0.949 0.772 – 1.17 0.62 97 958 all phecode
420.2 Pericarditis Circulatory System 1.03 0.955 – 1.1 0.474 842 8402 all phecode
420.21 Acute pericarditis Circulatory System 0.969 0.83 – 1.13 0.693 177 1764 all phecode
420.22 Chronic pericarditis Circulatory System 0.979 0.805 – 1.19 0.834 117 1153 all phecode
420.3 Endocarditis Circulatory System 1.01 0.94 – 1.09 0.716 764 7535 all phecode
425 Cardiomyopathy Circulatory System 1.05 1 – 1.1 0.0376 2078 19881 all phecode
425.1 Primary/intrinsic cardiomyopathies Circulatory System 1.05 0.998 – 1.1 0.0593 1989 19025 all phecode
425.11 Hypertrophic obstructive cardiomyopathy Circulatory System 1 0.866 – 1.15 0.997 208 2050 all phecode
425.12 Other hypertrophic cardiomyopathy Circulatory System 1.02 0.875 – 1.18 0.841 201 1992 all phecode
425.2 Secondary/extrinsic cardiomyopathies Circulatory System 0.984 0.876 – 1.1 0.783 317 3170 all phecode
425.8 Other cardiomyopathy Circulatory System 0.999 0.803 – 1.24 0.991 95 931 all phecode
426 Cardiac conduction disorders Circulatory System 1.02 0.992 – 1.04 0.199 12327 25440 all phecode
426.2 Atrioventricular [AV] block Circulatory System 1.02 0.968 – 1.07 0.491 1903 11501 all phecode
426.21 First degree AV block Circulatory System 1.01 0.956 – 1.08 0.632 1313 8899 all phecode
426.22 Mobitz II AV block Circulatory System 1.19 0.922 – 1.53 0.182 64 553 all phecode
426.23 Second degree AV block Circulatory System 1.01 0.876 – 1.17 0.867 216 1925 all phecode
426.24 Atrioventricular block, complete Circulatory System 1.04 0.945 – 1.15 0.404 461 3823 all phecode
426.25 Other heart block Circulatory System 1.06 0.909 – 1.23 0.458 203 1803 all phecode
426.3 Bundle branch block Circulatory System 1.05 0.998 – 1.09 0.0592 2306 13999 all phecode
426.31 Right bundle branch block Circulatory System 1.03 0.973 – 1.09 0.3 1423 10758 all phecode
426.32 Left bundle branch block Circulatory System 1.03 0.966 – 1.11 0.338 969 8110 all phecode
426.4 Anomalous atrioventricular excitation Circulatory System 1.01 0.802 – 1.28 0.906 82 820 all phecode
426.7 Abnormal electrocardiogram [ECG] [EKG] Circulatory System 1.02 0.991 – 1.04 0.207 10577 25186 all phecode
426.8 Other cardiac conduction disorders Circulatory System 0.967 0.893 – 1.05 0.417 679 6650 all phecode
426.9 Cardiac pacemaker/device in situ Circulatory System 1.03 0.974 – 1.08 0.337 1754 11536 all phecode
426.91 Cardiac pacemaker in situ Circulatory System 0.999 0.938 – 1.06 0.965 1171 8184 all phecode
426.92 Cardiac defibrillator in situ Circulatory System 1.05 0.977 – 1.13 0.179 846 7320 all phecode
427 Cardiac dysrhythmias Circulatory System 1.01 0.985 – 1.03 0.583 17397 25735 all phecode
427.1 Paroxysmal tachycardia, unspecified Circulatory System 1.04 0.992 – 1.08 0.106 2474 18178 all phecode
427.11 Paroxysmal supraventricular tachycardia Circulatory System 1.03 0.976 – 1.09 0.285 1595 14293 all phecode
427.12 Paroxysmal ventricular tachycardia Circulatory System 1.05 0.988 – 1.12 0.116 1181 9915 all phecode
427.2 Atrial fibrillation and flutter Circulatory System 1.01 0.973 – 1.04 0.729 5313 18688 all phecode
427.21 Atrial fibrillation Circulatory System 1.01 0.973 – 1.04 0.707 5188 18409 all phecode
427.22 Atrial flutter Circulatory System 1.02 0.962 – 1.07 0.578 1693 11042 all phecode
427.3 Other specified cardiac dysrhythmias Circulatory System 1.02 0.989 – 1.04 0.257 8688 25552 all phecode
427.4 Cardiac arrest and ventricular fibrillation Circulatory System 1 0.916 – 1.1 0.948 536 5233 all phecode
427.41 Ventricular fibrillation and flutter Circulatory System 1.12 0.965 – 1.29 0.14 216 2118 all phecode
427.42 Cardiac arrest Circulatory System 0.982 0.885 – 1.09 0.738 410 4034 all phecode
427.5 Arrhythmia (cardiac) NOS Circulatory System 1.01 0.978 – 1.04 0.663 6905 25457 all phecode
427.6 Premature beats Circulatory System 1.06 1.01 – 1.1 0.0181 2359 16248 all phecode
427.61 Supraventricular premature beats Circulatory System 1.03 0.948 – 1.12 0.487 670 6287 all phecode
427.7 Tachycardia NOS Circulatory System 1.01 0.977 – 1.04 0.637 5124 25531 all phecode
427.8 Sinoatrial node dysfunction (Bradycardia) Circulatory System 1.02 0.947 – 1.09 0.653 912 7501 all phecode
427.9 Palpitations Circulatory System 1.02 0.985 – 1.05 0.279 4430 24505 all phecode
428 Congestive heart failure; nonhypertensive Circulatory System 1.03 0.992 – 1.06 0.141 4300 23663 all phecode
428.1 Congestive heart failure (CHF) NOS Circulatory System 1.03 0.993 – 1.07 0.12 3756 22446 all phecode
428.2 Heart failure NOS Circulatory System 1.02 0.986 – 1.06 0.23 3701 21722 all phecode
428.3
Heart failure with reduced EF [Systolic or
Heart failure with reduced EF [Systolic or combined heart failure]
 Circulatory System 1.05 1 – 1.11 0.0431 1765 14476 all phecode
428.4
Heart failure with preserved EF [Diastolic
Heart failure with preserved EF [Diastolic heart failure]
 Circulatory System 0.996 0.945 – 1.05 0.872 1648 13395 all phecode
429
Ill-defined descriptions and complications of
Ill-defined descriptions and complications of heart disease
 Circulatory System 1.02 0.998 – 1.04 0.0794 12635 32504 all phecode
429.1 Heart transplant/surgery Circulatory System 1.08 1.02 – 1.15 0.0101 1219 11696 all phecode
429.2 Abnormal function study of cardiovascular system Circulatory System 1.03 1 – 1.06 0.0378 6322 29232 all phecode
429.3 Symptoms involving cardiovascular system Circulatory System 1.02 0.995 – 1.04 0.113 9650 32421 all phecode
429.9 Cardiac complications, not elsewhere classified Circulatory System 1.01 0.936 – 1.09 0.776 723 7072 all phecode
430 Intracranial hemorrhage Circulatory System 0.958 0.889 – 1.03 0.258 789 7842 all phecode
430.1 Subarachnoid hemorrhage Circulatory System 0.983 0.863 – 1.12 0.803 261 2610 all phecode
430.2 Intracerebral hemorrhage Circulatory System 0.94 0.844 – 1.05 0.257 368 3671 all phecode
430.3 Subdural hemorrhage Circulatory System 0.93 0.82 – 1.05 0.257 272 2680 all phecode
433 Cerebrovascular disease Circulatory System 1.04 1.01 – 1.07 0.00814 5463 32242 all phecode
433.1 Occlusion and stenosis of precerebral arteries Circulatory System 1.09 1.04 – 1.14 0.000513 1978 16212 all phecode
433.11
Occlusion of cerebral arteries, with cerebral
Occlusion of cerebral arteries, with cerebral infarction
 Circulatory System 1.06 0.936 – 1.21 0.342 260 2517 all phecode
433.12 Cerebral atherosclerosis Circulatory System 1.21 0.952 – 1.53 0.12 80 789 all phecode
433.2 Occlusion of cerebral arteries Circulatory System 1.03 0.987 – 1.08 0.17 2437 21732 all phecode
433.21
Cerebral artery occlusion, with cerebral
Cerebral artery occlusion, with cerebral infarction
 Circulatory System 1.03 0.989 – 1.08 0.14 2357 21103 all phecode
433.3 Cerebral ischemia Circulatory System 1.03 0.994 – 1.08 0.0962 2780 22868 all phecode
433.31 Transient cerebral ischemia Circulatory System 1.03 0.982 – 1.07 0.254 2409 20762 all phecode
433.5 Cerebral aneurysm Circulatory System 1.01 0.923 – 1.12 0.762 474 4724 all phecode
433.6 Acute, but ill-defined cerebrovascular disease Circulatory System 1.04 0.946 – 1.15 0.407 464 4518 all phecode
433.8 Late effects of cerebrovascular disease Circulatory System 1.01 0.934 – 1.09 0.791 695 6822 all phecode
440 Atherosclerosis Circulatory System 1.05 1 – 1.09 0.0315 2477 19724 all phecode
440.1 Atherosclerosis of renal artery Circulatory System 1.05 0.92 – 1.21 0.448 231 2291 all phecode
440.2 Atherosclerosis of the extremities Circulatory System 1.01 0.961 – 1.07 0.608 1516 13532 all phecode
440.21
Atherosclerosis of native arteries of the
Atherosclerosis of native arteries of the extremities with ulceration or gangrene
 Circulatory System 1.07 0.942 – 1.21 0.3 274 2669 all phecode
440.22
Atherosclerosis of native arteries of the
Atherosclerosis of native arteries of the extremities with intermittent claudication
 Circulatory System 1.02 0.957 – 1.09 0.53 1040 9647 all phecode
440.9 Atherosclerosis of aorta Circulatory System 1.11 1.03 – 1.19 0.00521 846 8124 all phecode
441 Vascular insufficiency of intestine Circulatory System 0.941 0.857 – 1.03 0.197 515 5115 all phecode
441.1 Acute vascular insufficiency of intestine Circulatory System 0.991 0.862 – 1.14 0.896 240 2387 all phecode
441.2 Chronic vascular insufficiency of intestine Circulatory System 0.941 0.795 – 1.11 0.482 154 1536 all phecode
442 Other aneurysm Circulatory System 1.01 0.969 – 1.05 0.648 2779 21466 all phecode
442.1 Aortic aneurysm Circulatory System 1.03 0.982 – 1.08 0.224 2054 16492 all phecode
442.11 Abdominal aortic aneurysm Circulatory System 1.07 1.01 – 1.14 0.0266 1189 10558 all phecode
442.2 Aneurysm of iliac artery Circulatory System 1.15 0.987 – 1.33 0.0732 202 2002 all phecode
442.3 Aneurysm of artery of lower extremity Circulatory System 1 0.86 – 1.17 0.967 179 1765 all phecode
442.4 Arterial dissection Circulatory System 0.962 0.826 – 1.12 0.623 184 1840 all phecode
442.8 Aneurysm of other specified artery Circulatory System 0.925 0.833 – 1.03 0.148 399 3978 all phecode
443 Peripheral vascular disease Circulatory System 1.03 0.992 – 1.07 0.12 3086 24814 all phecode
443.1 Raynaud's syndrome Circulatory System 0.984 0.91 – 1.06 0.676 742 7390 all phecode
443.7
Peripheral angiopathy in diseases classified
Peripheral angiopathy in diseases classified elsewhere
 Circulatory System 1.07 0.928 – 1.23 0.363 220 2087 all phecode
443.8 Other specified peripheral vascular diseases Circulatory System 1.03 0.985 – 1.07 0.215 2557 21985 all phecode
443.9 Peripheral vascular disease, unspecified Circulatory System 1.04 0.992 – 1.08 0.106 2341 18862 all phecode
444 Arterial embolism and thrombosis Circulatory System 1.01 0.936 – 1.08 0.87 848 8423 all phecode
444.1
Arterial embolism and thrombosis of lower
Arterial embolism and thrombosis of lower extremity artery
 Circulatory System 0.988 0.877 – 1.11 0.842 313 3099 all phecode
444.2 Embolism and thrombosis of abdominal aorta Circulatory System 1.18 0.995 – 1.4 0.0569 155 1548 all phecode
446 Polyarteritis nodosa and allied conditions Circulatory System 1.03 0.934 – 1.14 0.555 460 4559 all phecode
446.4 Wegener's granulomatosis Circulatory System 1.07 0.878 – 1.31 0.488 109 1075 all phecode
446.5 Giant cell arteritis Circulatory System 1.1 0.88 – 1.38 0.396 79 749 all phecode
446.9 Arteritis NOS Circulatory System 0.956 0.847 – 1.08 0.47 289 2876 all phecode
447 Other disorders of arteries and arterioles Circulatory System 1.04 0.994 – 1.08 0.0926 2647 22765 all phecode
447.1 Stricture of artery Circulatory System 1.01 0.925 – 1.11 0.776 523 5163 all phecode
447.7 Aortic ectasia Circulatory System 1 0.933 – 1.08 0.913 804 7938 all phecode
448 Disease of capillaries Circulatory System 0.977 0.92 – 1.04 0.436 1237 12127 all phecode
450 Noninfectious disorders of lymphatic channels Circulatory System 0.965 0.922 – 1.01 0.13 2104 20985 all phecode
451 Phlebitis and thrombophlebitis Circulatory System 0.941 0.871 – 1.02 0.125 738 7355 all phecode
451.2
Phlebitis and thrombophlebitis of lower
Phlebitis and thrombophlebitis of lower extremities
 Circulatory System 0.937 0.82 – 1.07 0.341 244 2437 all phecode
452 Other venous embolism and thrombosis Circulatory System 0.97 0.941 – 1 0.0547 4957 29867 all phecode
452.1 Iatrogenic pulmonary embolism and infarction Circulatory System 0.981 0.863 – 1.11 0.766 276 2747 all phecode
452.2 Deep vein thrombosis [DVT] Circulatory System 0.96 0.925 – 0.996 0.0307 3260 26940 all phecode
452.8 Postphlebitic syndrome Circulatory System 1.02 0.861 – 1.2 0.833 154 1529 all phecode
453 Chronic venous hypertension Circulatory System 0.967 0.842 – 1.11 0.636 220 2168 all phecode
454 Varicose veins Circulatory System 0.95 0.913 – 0.988 0.0114 2827 24555 all phecode
454.1 Varicose veins of lower extremity Circulatory System 0.947 0.908 – 0.989 0.0128 2469 21426 all phecode
454.11 Varicose veins of lower extremity, symptomtic Circulatory System 0.929 0.881 – 0.98 0.00686 1565 15056 all phecode
455 Hemorrhoids Circulatory System 1.04 1.01 – 1.07 0.0214 5799 29818 all phecode
456 Chronic venous insufficiency [CVI] Circulatory System 0.965 0.928 – 1 0.0658 3097 24898 all phecode
457
Encounter for long-term (current) use of
Encounter for long-term (current) use of anticoagulants, antithrombotics, aspirin
 Circulatory System 1.06 1.01 – 1.11 0.017 2095 15309 all phecode
457.2
Encounter for long-term (current) use of
Encounter for long-term (current) use of antiplatelets/antithrombotics
 Circulatory System 1.09 0.973 – 1.23 0.136 324 3221 all phecode
457.3 Encounter for long-term (current) use of aspirin Circulatory System 1.06 1.01 – 1.11 0.0202 1973 14689 all phecode
458 Hypotension Circulatory System 1 0.974 – 1.03 0.81 5091 32185 all phecode
458.1 Orthostatic hypotension Circulatory System 0.943 0.89 – 0.999 0.0445 1344 12938 all phecode
458.2 Iatrogenic hypotension Circulatory System 0.983 0.923 – 1.05 0.605 1109 11012 all phecode
458.9 Hypotension NOS Circulatory System 1 0.972 – 1.04 0.811 4618 31186 all phecode
459 Other disorders of circulatory system Circulatory System 1.01 0.981 – 1.03 0.622 7825 34792 all phecode
459.1 Hemorrhage NOS Circulatory System 0.979 0.911 – 1.05 0.571 834 8215 all phecode
459.7 Blood vessel replaced Circulatory System 0.973 0.918 – 1.03 0.345 1305 13023 all phecode
459.9 Circulatory disease NEC Circulatory System 1.01 0.986 – 1.04 0.327 6706 33592 all phecode
464 Acute sinusitis Respiratory 1 0.972 – 1.04 0.837 4792 32137 all phecode
465
Acute upper respiratory infections of multiple
Acute upper respiratory infections of multiple or unspecified sites
 Respiratory 1.01 0.984 – 1.03 0.556 9601 35915 all phecode
465.2 Acute pharyngitis Respiratory 1 0.971 – 1.03 0.945 5310 32365 all phecode
465.4 Acute laryngitis and tracheitis Respiratory 1.06 0.96 – 1.17 0.244 443 4428 all phecode
470 Septal Deviations/Turbinate Hypertrophy Respiratory 0.954 0.907 – 1 0.0616 1797 17640 all phecode
471 Nasal polyps Respiratory 1.01 0.928 – 1.1 0.798 592 5881 all phecode
472 Chronic pharyngitis and nasopharyngitis Respiratory 0.982 0.934 – 1.03 0.485 1797 16986 all phecode
473 Diseases of the larynx and vocal cords Respiratory 0.998 0.96 – 1.04 0.923 2983 25244 all phecode
473.1 Chronic laryngitis Respiratory 0.936 0.734 – 1.19 0.594 68 674 all phecode
473.3 Paralysis/spasm of vocal cords or larynx Respiratory 1.05 0.968 – 1.14 0.231 628 6254 all phecode
473.4 Voice disturbance Respiratory 1.01 0.964 – 1.05 0.744 2336 21975 all phecode
474 Acute and chronic tonsillitis Respiratory 0.989 0.921 – 1.06 0.767 880 7892 all phecode
474.1 Acute tonsillitis Respiratory 0.992 0.883 – 1.11 0.89 335 3181 all phecode
474.2 Chronic tonsillitis and adenoiditis Respiratory 1 0.927 – 1.09 0.912 700 6445 all phecode
475 Chronic sinusitis Respiratory 0.996 0.964 – 1.03 0.797 4378 27891 all phecode
475.9 Postnasal drip Respiratory 0.988 0.921 – 1.06 0.724 922 9017 all phecode
476 Allergic rhinitis Respiratory 0.993 0.972 – 1.02 0.554 12687 28117 all phecode
477 Epistaxis or throat hemorrhage Respiratory 1.07 1 – 1.14 0.0369 1150 11318 all phecode
478 Throat pain Respiratory 1.03 0.925 – 1.14 0.632 426 4195 all phecode
479 Other upper respiratory disease Respiratory 0.998 0.969 – 1.03 0.879 5627 28048 all phecode
480 Pneumonia Respiratory 1.03 1 – 1.06 0.0509 5947 37034 all phecode
480.1 Bacterial pneumonia Respiratory 1.05 0.988 – 1.12 0.117 1155 11495 all phecode
480.11 Pneumococcal pneumonia Respiratory 1.05 0.958 – 1.14 0.309 568 5644 all phecode
480.12 Pseudomonal pneumonia Respiratory 1.16 0.974 – 1.37 0.0964 153 1523 all phecode
480.13 MRSA pneumonia Respiratory 0.89 0.729 – 1.09 0.251 117 1165 all phecode
480.2 Viral pneumonia Respiratory 1.07 0.927 – 1.23 0.359 202 1992 all phecode
480.3 Pneumonia due to fungus (mycoses) Respiratory 1.05 0.896 – 1.24 0.537 159 1590 all phecode
480.5 Bronchopneumonia and lung abscess Respiratory 0.941 0.791 – 1.12 0.492 135 1312 all phecode
481 Influenza Respiratory 0.988 0.933 – 1.05 0.68 1355 13284 all phecode
483 Acute bronchitis and bronchiolitis Respiratory 1 0.966 – 1.04 0.918 3412 29871 all phecode
495 Asthma Respiratory 0.99 0.966 – 1.01 0.405 8671 33569 all phecode
495.1 Chronic obstructive asthma Respiratory 0.994 0.896 – 1.1 0.916 397 3925 all phecode
495.11 Chronic obstructive asthma with exacerbation Respiratory 1.08 0.86 – 1.36 0.504 81 802 all phecode
495.2 Asthma with exacerbation Respiratory 0.999 0.948 – 1.05 0.957 1629 16033 all phecode
496 Chronic airway obstruction Respiratory 1.01 0.98 – 1.04 0.534 5343 28343 all phecode
496.1 Emphysema Respiratory 1.02 0.979 – 1.07 0.293 2134 19414 all phecode
496.2 Chronic bronchitis Respiratory 1.01 0.973 – 1.04 0.703 4128 26624 all phecode
496.21 Obstructive chronic bronchitis Respiratory 1.02 0.981 – 1.05 0.388 3747 25467 all phecode
496.3 Bronchiectasis Respiratory 1.06 0.969 – 1.16 0.206 549 5453 all phecode
497 Bronchitis Respiratory 0.991 0.945 – 1.04 0.718 1946 18824 all phecode
498 Acute bronchospasm Respiratory 0.949 0.864 – 1.04 0.28 496 4943 all phecode
499 Cystic fibrosis Respiratory 0.95 0.802 – 1.13 0.554 151 1510 all phecode
500 Lung disease due to external agents Respiratory 0.933 0.854 – 1.02 0.124 557 5551 all phecode
500.1 Extrinsic allergic alveolitis Respiratory 1.01 0.811 – 1.25 0.938 92 920 all phecode
500.2 Pneumoconiosis Respiratory 0.92 0.745 – 1.14 0.442 78 764 all phecode
501 Pneumonitis due to inhalation of food or vomitus Respiratory 1.03 0.948 – 1.12 0.488 634 6225 all phecode
502 Postinflammatory pulmonary fibrosis Respiratory 0.993 0.921 – 1.07 0.842 815 8076 all phecode
503 Pulmonary congestion and hypostasis Respiratory 0.993 0.924 – 1.07 0.856 835 8243 all phecode
504 Other alveolar and parietoalveolar pneumonopathy Respiratory 0.97 0.89 – 1.06 0.499 595 5878 all phecode
504.1 Idiopathic fibrosing alveolitis Respiratory 1.04 0.919 – 1.17 0.567 311 3084 all phecode
505 Other pulmonary inflamation or edema Respiratory 1 0.951 – 1.06 0.941 1638 15749 all phecode
506 Empyema and pneumothorax Respiratory 1.03 0.993 – 1.08 0.105 2894 25235 all phecode
507 Pleurisy; pleural effusion Respiratory 0.994 0.956 – 1.03 0.771 2916 26208 all phecode
508
Pulmonary collapse; interstitial and
Pulmonary collapse; interstitial and compensatory emphysema
 Respiratory 1.01 0.963 – 1.05 0.79 2382 22588 all phecode
509 Respiratory failure, insufficiency, arrest Respiratory 1.03 0.992 – 1.06 0.135 4032 29477 all phecode
509.1 Respiratory failure Respiratory 0.988 0.942 – 1.04 0.609 1937 18949 all phecode
509.2 Respiratory insufficiency Respiratory 1.01 0.948 – 1.07 0.812 1174 11679 all phecode
509.3
Pulmonary insufficiency or respiratory failure
Pulmonary insufficiency or respiratory failure following trauma and surgery
 Respiratory 1.01 0.959 – 1.06 0.713 1689 16489 all phecode
509.8
Dependence on respirator [Ventilator] or
Dependence on respirator [Ventilator] or supplemental oxygen
 Respiratory 1.04 0.992 – 1.1 0.0968 1741 17249 all phecode
510 Other diseases of lung Respiratory 1 0.975 – 1.03 0.771 5503 35907 all phecode
510.2 Lung transplant Respiratory 1.06 0.905 – 1.23 0.487 176 1757 all phecode
512 Other symptoms of respiratory system Respiratory 1.01 0.991 – 1.03 0.281 18621 28154 all phecode
512.1 Wheezing Respiratory 0.997 0.942 – 1.05 0.911 1409 13516 all phecode
512.2 Painful respiration Respiratory 0.999 0.956 – 1.04 0.96 2309 21263 all phecode
512.3 Abnormal chest sounds Respiratory 1.01 0.894 – 1.15 0.848 291 2845 all phecode
512.7 Shortness of breath Respiratory 1.02 0.996 – 1.04 0.105 10034 28081 all phecode
512.8 Cough Respiratory 0.996 0.973 – 1.02 0.771 9501 28148 all phecode
512.9 Other dyspnea Respiratory 1.02 0.994 – 1.04 0.151 10804 28104 all phecode
513 Respiratory abnormalities Respiratory 1 0.981 – 1.02 0.895 12932 33822 all phecode
513.3 Hypoventilation Respiratory 0.95 0.885 – 1.02 0.153 880 8646 all phecode
513.31 Apnea Respiratory 0.997 0.905 – 1.1 0.956 462 4607 all phecode
513.32 Orthopnea Respiratory 0.892 0.777 – 1.02 0.104 220 2160 all phecode
513.4 Hyperventilation Respiratory 1.05 0.957 – 1.15 0.308 515 5124 all phecode
513.8 Disorders of diaphragm Respiratory 0.962 0.846 – 1.09 0.555 258 2557 all phecode
514 Abnormal findings examination of lungs Respiratory 1.01 0.978 – 1.04 0.636 5365 34834 all phecode
514.1
Abnormal results of function study of pulmonary
Abnormal results of function study of pulmonary system
 Respiratory 1.03 0.902 – 1.17 0.688 258 2580 all phecode
514.2 Solitary pulmonary nodule Respiratory 1.02 0.977 – 1.05 0.44 3018 27338 all phecode
516 Abnormal sputum Respiratory 0.973 0.9 – 1.05 0.5 735 7332 all phecode
516.1 Hemoptysis Respiratory 0.959 0.881 – 1.04 0.339 611 6080 all phecode
519
Other diseases of respiratory system, not
Other diseases of respiratory system, not elsewhere classified
 Respiratory 1.01 0.983 – 1.04 0.483 6458 39057 all phecode
519.1 Tracheostomy complications Respiratory 0.997 0.863 – 1.15 0.966 214 2136 all phecode
519.2 Respiratory complications Respiratory 0.984 0.891 – 1.09 0.754 445 4430 all phecode
519.8 Other diseases of respiratory system, NEC Respiratory 0.998 0.946 – 1.05 0.945 1588 15787 all phecode
519.9
Symptoms involving respiratory system and other
Symptoms involving respiratory system and other chest symptoms
 Respiratory 1.02 0.984 – 1.05 0.34 4706 34489 all phecode
520 Disorders of tooth development Digestive 1.02 0.916 – 1.14 0.695 369 3690 all phecode
520.1 Hereditary disturbances in tooth structure Digestive 1.04 0.884 – 1.23 0.618 165 1642 all phecode
520.2 Disturbances in tooth eruption Digestive 1.02 0.882 – 1.18 0.804 218 2172 all phecode
521 Diseases of hard tissues of teeth Digestive 0.963 0.897 – 1.03 0.292 898 8954 all phecode
521.1 Dental caries Digestive 0.961 0.894 – 1.03 0.282 837 8349 all phecode
521.2 Dental abrasion, erosion and attrition Digestive 0.968 0.719 – 1.3 0.828 52 510 all phecode
522 Diseases of pulp and periapical tissues Digestive 1.05 0.954 – 1.15 0.339 535 5340 all phecode
522.5 Periapical abscess Digestive 1.01 0.919 – 1.12 0.775 459 4583 all phecode
523 Gingival and periodontal diseases Digestive 0.995 0.921 – 1.07 0.893 718 7180 all phecode
523.1 Gingivitis Digestive 0.821 0.689 – 0.979 0.0282 142 1418 all phecode
523.3 Periodontitis (acute or chronic) Digestive 1.02 0.919 – 1.14 0.666 364 3636 all phecode
523.31 Acute periodontitis Digestive 0.976 0.868 – 1.1 0.689 311 3109 all phecode
523.32 Chronic periodontitis Digestive 1.13 0.932 – 1.36 0.217 122 1204 all phecode
524 Dentofacial anomalies, including malocclusion Digestive 1.03 0.919 – 1.14 0.652 363 3630 all phecode
524.3 Anomalies of tooth position/malocclusion Digestive 1.08 0.941 – 1.25 0.267 220 2200 all phecode
525
Other diseases of the teeth and supporting
Other diseases of the teeth and supporting structures
 Digestive 1 0.941 – 1.07 0.893 1039 10382 all phecode
525.1 Loss of teeth or edentulism Digestive 0.937 0.84 – 1.05 0.246 374 3731 all phecode
526 Diseases of the jaws Digestive 0.993 0.954 – 1.03 0.746 2680 26455 all phecode
526.1 Cysts of the jaws Digestive 0.948 0.828 – 1.08 0.436 247 2470 all phecode
526.3 Anomalies of jaw size/symmetry Digestive 1 0.875 – 1.15 0.992 241 2383 all phecode
526.4 Temporomandibular joint disorders Digestive 0.997 0.944 – 1.05 0.915 1504 15025 all phecode
526.41 Temporomandibular joint disorder, unspecified Digestive 0.984 0.925 – 1.05 0.596 1187 11858 all phecode
526.42 Arthralgia/ankylosis of temporomandibular joint Digestive 1.03 0.955 – 1.11 0.435 741 7400 all phecode
526.5 Inflammatory conditions of jaw Digestive 1.06 0.934 – 1.2 0.372 287 2864 all phecode
526.8 Exostosis of jaw Digestive 1.2 0.901 – 1.61 0.208 53 521 all phecode
526.9 Jaw disease NOS Digestive 0.951 0.864 – 1.05 0.303 487 4867 all phecode
527 Diseases of the salivary glands Digestive 0.969 0.922 – 1.02 0.212 1781 17771 all phecode
527.1 Hypertrophy of salivary gland Digestive 1 0.764 – 1.32 0.982 58 579 all phecode
527.2 Sialoadenitis Digestive 0.995 0.895 – 1.11 0.929 394 3936 all phecode
527.7 Disturbance of salivary secretion Digestive 0.991 0.926 – 1.06 0.801 952 9481 all phecode
527.8 Other specified diseases of the salivary glands Digestive 1.01 0.883 – 1.15 0.911 254 2540 all phecode
528
Diseases of the oral soft tissues, excluding
Diseases of the oral soft tissues, excluding lesions specific for gingiva and tongue
 Digestive 0.969 0.93 – 1.01 0.128 2643 26197 all phecode
528.1 Stomatitis and mucositis Digestive 0.883 0.814 – 0.957 0.00252 668 6657 all phecode
528.11 Stomatitis and mucositis (ulcerative) Digestive 0.848 0.738 – 0.976 0.021 211 2110 all phecode
528.12 Oral aphthae Digestive 0.929 0.806 – 1.07 0.308 215 2137 all phecode
528.3 Cellulitis and abscess of oral soft tissues Digestive 0.961 0.838 – 1.1 0.566 235 2338 all phecode
528.4 Cysts of oral soft tissues Digestive 1.09 0.899 – 1.31 0.392 124 1229 all phecode
528.41 Cyst of the salivary gland Digestive 0.971 0.766 – 1.23 0.81 77 760 all phecode
528.5 Diseases of lips Digestive 0.966 0.877 – 1.06 0.486 462 4602 all phecode
528.6 Leukoplakia of oral mucosa Digestive 0.918 0.77 – 1.1 0.346 137 1370 all phecode
528.7 Sialolithiasis Digestive 1.01 0.855 – 1.18 0.947 163 1623 all phecode
529 Diseases and other conditions of the tongue Digestive 0.993 0.917 – 1.08 0.863 690 6878 all phecode
529.1 Glossitis Digestive 0.95 0.792 – 1.14 0.584 129 1281 all phecode
529.6 Glossodynia Digestive 0.88 0.747 – 1.04 0.128 168 1652 all phecode
530 Diseases of esophagus Digestive 0.984 0.965 – 1 0.118 17081 27931 all phecode
530.1 Esophagitis, GERD and related diseases Digestive 0.984 0.964 – 1 0.117 16572 27931 all phecode
530.11 GERD Digestive 0.982 0.962 – 1 0.0795 16143 27929 all phecode
530.12 Ulcer of esophagus Digestive 1.05 0.943 – 1.17 0.373 400 3983 all phecode
530.13 Barrett's esophagus Digestive 0.978 0.906 – 1.06 0.562 762 7584 all phecode
530.14 Reflux esophagitis Digestive 0.958 0.912 – 1.01 0.0819 1900 17495 all phecode
530.15 Eosinophilic esophagitis Digestive 0.829 0.719 – 0.955 0.00957 221 2210 all phecode
530.2 Esophageal bleeding (varices/hemorrhage) Digestive 0.926 0.852 – 1.01 0.0673 651 6473 all phecode
530.3 Stricture and stenosis of esophagus Digestive 1.04 0.967 – 1.11 0.307 911 8971 all phecode
530.5 Disorders of esophageal motility Digestive 1.02 0.934 – 1.12 0.624 548 5432 all phecode
530.6 Diverticulum of esophagus, acquired Digestive 1.04 0.862 – 1.26 0.675 129 1265 all phecode
530.7 Gastroesophageal laceration-hemorrhage syndrome Digestive 0.766 0.605 – 0.971 0.0277 82 812 all phecode
530.9 Heartburn Digestive 0.973 0.922 – 1.03 0.323 1519 14928 all phecode
531 Peptic ulcer (excl. esophageal) Digestive 0.969 0.925 – 1.01 0.176 2073 20617 all phecode
531.1 Hemorrhage from gastrointestinal ulcer Digestive 0.939 0.847 – 1.04 0.236 391 3883 all phecode
531.2 Gastric ulcer Digestive 0.96 0.904 – 1.02 0.193 1201 11970 all phecode
531.3 Duodenal ulcer Digestive 0.999 0.908 – 1.1 0.979 467 4640 all phecode
531.4 Peptic ulcer, site unspecified Digestive 0.916 0.851 – 0.986 0.0191 804 8018 all phecode
531.5 Gastrojejunal ulcer Digestive 1.02 0.859 – 1.21 0.825 150 1500 all phecode
532 Dysphagia Digestive 0.978 0.949 – 1.01 0.146 5585 26852 all phecode
535 Gastritis and duodenitis Digestive 0.984 0.945 – 1.02 0.414 2799 27335 all phecode
535.1 Acute gastritis Digestive 0.976 0.918 – 1.04 0.438 1178 11750 all phecode
535.2 Atrophic gastritis Digestive 0.98 0.874 – 1.1 0.732 344 3413 all phecode
535.6 Duodenitis Digestive 0.955 0.853 – 1.07 0.416 334 3337 all phecode
535.8 Other specified gastritis Digestive 0.953 0.877 – 1.04 0.257 638 6354 all phecode
535.9 Gastritis and duodenitis, NOS Digestive 0.94 0.886 – 0.997 0.0398 1255 12511 all phecode
536 Disorders of function of stomach Digestive 0.983 0.945 – 1.02 0.38 2911 27685 all phecode
536.3 Gastroparesis Digestive 1.04 0.962 – 1.13 0.314 706 6901 all phecode
536.7
Complications of gastrostomy, colostomy and
Complications of gastrostomy, colostomy and enterostomy
 Digestive 0.957 0.864 – 1.06 0.396 407 4059 all phecode
536.8
Dyspepsia and other specified disorders of
Dyspepsia and other specified disorders of function of stomach
 Digestive 0.969 0.926 – 1.01 0.182 2150 21094 all phecode
537 Other disorders of stomach and duodenum Digestive 1 0.964 – 1.04 0.977 3183 30048 all phecode
537.1 Lesions of stomach and duodenum Digestive 1.07 0.918 – 1.25 0.391 173 1725 all phecode
539 Bariatric surgery Digestive 0.914 0.866 – 0.964 0.00104 1509 15074 all phecode
540 Appendiceal conditions Digestive 1.04 0.942 – 1.14 0.461 495 4948 all phecode
540.1 Appendicitis Digestive 1.04 0.937 – 1.15 0.473 425 4239 all phecode
540.11 Acute appendicitis Digestive 1.04 0.934 – 1.17 0.448 353 3511 all phecode
550 Abdominal hernia Digestive 1 0.974 – 1.03 0.986 6768 37731 all phecode
550.1 Inguinal hernia Digestive 0.994 0.945 – 1.05 0.828 1744 16488 all phecode
550.2 Diaphragmatic hernia Digestive 1 0.962 – 1.04 0.969 2817 25849 all phecode
550.3 Femoral hernia Digestive 0.941 0.786 – 1.13 0.513 131 1291 all phecode
550.4 Umbilical hernia Digestive 0.974 0.919 – 1.03 0.385 1313 13110 all phecode
550.5 Ventral hernia Digestive 0.984 0.941 – 1.03 0.484 2241 22163 all phecode
550.6 Incisional hernia Digestive 0.99 0.934 – 1.05 0.743 1313 13111 all phecode
555
Inflammatory bowel disease and other
Inflammatory bowel disease and other gastroenteritis and colitis
 Digestive 1.01 0.957 – 1.07 0.724 1536 15153 all phecode
555.1 Regional enteritis Digestive 1 0.935 – 1.08 0.943 919 9095 all phecode
555.2 Ulcerative colitis Digestive 1.02 0.947 – 1.09 0.673 937 9315 all phecode
555.21 Ulcerative colitis (chronic) Digestive 1.04 0.952 – 1.15 0.356 537 5315 all phecode
556 Ulceration of the lower GI tract Digestive 0.97 0.891 – 1.06 0.477 632 6267 all phecode
556.1 Ulceration of intestine Digestive 0.995 0.909 – 1.09 0.912 551 5451 all phecode
556.11
Angiodysplasia of intestine (without mention of
Angiodysplasia of intestine (without mention of hemorrhage)
 Digestive 1.01 0.878 – 1.17 0.853 214 2093 all phecode
557 Intestinal malabsorption (non-celiac) Digestive 0.96 0.913 – 1.01 0.121 1716 16490 all phecode
557.1 Celiac disease Digestive 0.952 0.859 – 1.06 0.347 421 4026 all phecode
558 Noninfectious gastroenteritis Digestive 1 0.969 – 1.04 0.794 3458 26408 all phecode
559 Ileostomy status Digestive 1.02 0.955 – 1.1 0.518 957 9565 all phecode
560 Intestinal obstruction without mention of hernia Digestive 0.998 0.96 – 1.04 0.923 3004 24851 all phecode
560.1 Paralytic ileus Digestive 1.02 0.967 – 1.07 0.489 1627 15714 all phecode
560.2 Impaction of intestine Digestive 0.913 0.819 – 1.02 0.0982 387 3779 all phecode
560.3 Peritoneal or intestinal adhesions Digestive 0.871 0.766 – 0.99 0.0344 266 2647 all phecode
560.4 Other intestinal obstruction Digestive 0.977 0.928 – 1.03 0.38 1651 16170 all phecode
561 Symptoms involving digestive system Digestive 0.969 0.929 – 1.01 0.14 2608 21766 all phecode
562 Diverticulosis and diverticulitis Digestive 0.984 0.956 – 1.01 0.277 6295 23431 all phecode
562.1 Diverticulosis Digestive 0.987 0.958 – 1.02 0.375 6246 23383 all phecode
562.2 Diverticulitis Digestive 0.961 0.912 – 1.01 0.139 1611 15162 all phecode
564 Functional digestive disorders Digestive 1 0.979 – 1.02 0.929 11411 28676 all phecode
564.1 Irritable Bowel Syndrome Digestive 0.992 0.956 – 1.03 0.654 3457 22266 all phecode
564.9 Personal history of diseases of digestive system Digestive 0.996 0.958 – 1.04 0.84 3074 25861 all phecode
565 Anal and rectal conditions Digestive 1.01 0.977 – 1.05 0.492 3355 30757 all phecode
565.1 Anal and rectal polyp Digestive 0.982 0.926 – 1.04 0.541 1305 12649 all phecode
567 Peritonitis and retroperitoneal infections Digestive 0.982 0.928 – 1.04 0.521 1364 13616 all phecode
568 Other disorders of peritoneum Digestive 0.958 0.911 – 1.01 0.094 1705 17038 all phecode
568.1
Peritoneal adhesions (postoperative)
Peritoneal adhesions (postoperative) (postinfection)
 Digestive 0.94 0.886 – 0.997 0.0405 1247 12468 all phecode
569 Other disorders of intestine Digestive 0.995 0.97 – 1.02 0.693 8079 35231 all phecode
569.1 Toxic gastroenteritis and colitis Digestive 1.1 0.98 – 1.24 0.103 326 3260 all phecode
569.2 Gastrointestinal complications Digestive 0.949 0.897 – 1 0.068 1395 13933 all phecode
571 Chronic liver disease and cirrhosis Digestive 0.992 0.961 – 1.02 0.607 4610 32562 all phecode
571.5 Other chronic nonalcoholic liver disease Digestive 0.989 0.957 – 1.02 0.504 4342 32234 all phecode
571.51 Cirrhosis of liver without mention of alcohol Digestive 0.949 0.889 – 1.01 0.117 1018 10095 all phecode
571.6 Primary biliary cirrhosis Digestive 0.931 0.797 – 1.09 0.366 179 1790 all phecode
571.8
Liver abscess and sequelae of chronic liver
Liver abscess and sequelae of chronic liver disease
 Digestive 0.98 0.916 – 1.05 0.559 950 9498 all phecode
571.81 Portal hypertension Digestive 0.908 0.833 – 0.99 0.0293 573 5730 all phecode
572 Ascites (non malignant) Digestive 0.952 0.911 – 0.995 0.0276 2278 22675 all phecode
573 Other disorders of liver Digestive 0.994 0.965 – 1.02 0.675 5599 33620 all phecode
573.1 Chronic passive congestion of liver Digestive 0.793 0.658 – 0.957 0.0154 136 1359 all phecode
573.2 Liver replaced by transplant Digestive 0.99 0.876 – 1.12 0.867 292 2920 all phecode
573.3 Hepatomegaly Digestive 0.901 0.819 – 0.993 0.0351 470 4700 all phecode
573.4 Acute and subacute necrosis of liver Digestive 1.04 0.926 – 1.17 0.492 316 3149 all phecode
573.5 Jaundice (not of newborn) Digestive 0.952 0.889 – 1.02 0.161 958 9496 all phecode
573.6
Nonspecific elevation of levels of transaminase
Nonspecific elevation of levels of transaminase or lactic acid dehydrogenase [LDH]
 Digestive 0.985 0.946 – 1.03 0.463 2756 26470 all phecode
573.7 Abnormal results of function study of liver Digestive 0.983 0.946 – 1.02 0.393 3018 27774 all phecode
573.9 Abnormal serum enzyme levels Digestive 0.991 0.961 – 1.02 0.587 4679 33866 all phecode
574 Cholelithiasis and cholecystitis Digestive 0.946 0.912 – 0.982 0.0037 3177 30809 all phecode
574.1 Cholelithiasis Digestive 0.947 0.911 – 0.984 0.00566 2924 28874 all phecode
574.11 Cholelithiasis with acute cholecystitis Digestive 0.921 0.822 – 1.03 0.155 342 3412 all phecode
574.12 Cholelithiasis with other cholecystitis Digestive 0.966 0.884 – 1.06 0.445 553 5501 all phecode
574.2 Calculus of bile duct Digestive 0.947 0.881 – 1.02 0.135 852 8503 all phecode
574.3 Cholecystitis without cholelithiasis Digestive 0.931 0.866 – 1 0.0538 822 8181 all phecode
575 Other biliary tract disease Digestive 0.958 0.916 – 1 0.0561 2266 22555 all phecode
575.1 Cholangitis Digestive 0.978 0.876 – 1.09 0.688 354 3530 all phecode
575.2 Obstruction of bile duct Digestive 0.939 0.862 – 1.02 0.147 621 6201 all phecode
575.6 Cholesterolosis of gallbladder Digestive 0.997 0.86 – 1.16 0.969 207 2063 all phecode
575.7 Other disorders of gallbladder Digestive 0.932 0.871 – 0.997 0.0419 939 9382 all phecode
575.8 Other disorders of biliary tract Digestive 0.935 0.879 – 0.995 0.0329 1154 11523 all phecode
575.9
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of biliary tract
 Digestive 0.942 0.828 – 1.07 0.362 260 2600 all phecode
577 Diseases of pancreas Digestive 0.932 0.892 – 0.975 0.00205 2225 22106 all phecode
577.1 Acute pancreatitis Digestive 0.894 0.841 – 0.949 0.000258 1212 12110 all phecode
577.2 Chronic pancreatitis Digestive 0.884 0.805 – 0.971 0.01 495 4950 all phecode
577.3 Cyst and pseudocyst of pancreas Digestive 0.936 0.855 – 1.02 0.144 570 5601 all phecode
578 Gastrointestinal hemorrhage Digestive 0.986 0.956 – 1.02 0.391 4554 37045 all phecode
578.1 Hematemesis Digestive 0.991 0.901 – 1.09 0.845 485 4842 all phecode
578.2 Blood in stool Digestive 0.967 0.929 – 1.01 0.105 2743 26554 all phecode
578.8 Hemorrhage of rectum and anus Digestive 1.01 0.962 – 1.05 0.796 2210 21750 all phecode
578.9 Hemorrhage of gastrointestinal tract Digestive 0.967 0.917 – 1.02 0.224 1562 15345 all phecode
579 Other symptoms involving abdomen and pelvis Digestive 0.989 0.958 – 1.02 0.502 4431 34209 all phecode
579.2 Splenomegaly Digestive 0.99 0.916 – 1.07 0.808 730 7262 all phecode
579.8 Nonspecific abnormal findings in stool contents Digestive 0.991 0.937 – 1.05 0.756 1410 13877 all phecode
580 Nephritis; nephrosis; renal sclerosis Genitourinary 0.979 0.931 – 1.03 0.397 1881 15516 all phecode
580.1 Glomerulonephritis Genitourinary 1.02 0.918 – 1.14 0.702 401 3992 all phecode
580.11 Proliferative glomerulonephritis Genitourinary 1.02 0.859 – 1.21 0.823 146 1440 all phecode
580.12 Non-proliferative glomerulonephritis Genitourinary 0.965 0.79 – 1.18 0.73 114 1128 all phecode
580.13 Acute glomerulonephritis, NOS Genitourinary 0.885 0.675 – 1.16 0.376 61 600 all phecode
580.14 Chronic glomerulonephritis, NOS Genitourinary 1.03 0.91 – 1.17 0.612 277 2760 all phecode
580.2
Nephrotic syndrome without mention of
Nephrotic syndrome without mention of glomerulonephritis
 Genitourinary 0.981 0.851 – 1.13 0.797 221 2193 all phecode
580.3
Nephritis and nephropathy without mention of
Nephritis and nephropathy without mention of glomerulonephritis
 Genitourinary 0.979 0.926 – 1.03 0.444 1502 11930 all phecode
580.31
Nephritis and nephropathy in diseases
Nephritis and nephropathy in diseases classified elsewhere
 Genitourinary 0.94 0.877 – 1.01 0.0786 992 7228 all phecode
580.32
Nephritis and nephropathy with pathological
Nephritis and nephropathy with pathological lesion
 Genitourinary 1.02 0.941 – 1.11 0.627 683 6612 all phecode
580.4 Renal sclerosis, NOS Genitourinary 0.997 0.889 – 1.12 0.959 340 3400 all phecode
585 Renal failure Genitourinary 0.972 0.947 – 0.998 0.0382 7470 32340 all phecode
585.1 Acute renal failure Genitourinary 0.978 0.946 – 1.01 0.187 4265 27230 all phecode
585.2 Renal failure NOS Genitourinary 0.939 0.873 – 1.01 0.0914 832 8162 all phecode
585.3 Chronic renal failure [CKD] Genitourinary 0.976 0.947 – 1.01 0.106 5580 29470 all phecode
585.31 Renal dialysis Genitourinary 0.923 0.855 – 0.996 0.0395 747 7423 all phecode
585.32 End stage renal disease Genitourinary 0.955 0.894 – 1.02 0.174 1007 9783 all phecode
585.33 Chronic Kidney Disease, Stage III Genitourinary 0.985 0.948 – 1.02 0.45 3209 21312 all phecode
585.34 Chronic Kidney Disease, Stage IV Genitourinary 0.948 0.887 – 1.01 0.118 977 9190 all phecode
585.4 Chronic kidney disease, Stage I or II Genitourinary 0.965 0.908 – 1.02 0.242 1227 11191 all phecode
586 Other disorders of the kidney and ureters Genitourinary 0.995 0.969 – 1.02 0.691 7628 34189 all phecode
586.1 Anatomical abnormatilies of kidney and ureters Genitourinary 1 0.895 – 1.12 0.998 349 3480 all phecode
586.11 Small kidney Genitourinary 1.04 0.899 – 1.21 0.585 210 2093 all phecode
586.12 Vesicoureteral reflux Genitourinary 0.94 0.788 – 1.12 0.496 136 1360 all phecode
586.2 Cyst of kidney, acquired Genitourinary 0.966 0.913 – 1.02 0.23 1381 12912 all phecode
586.3 Vascular disorders of kidney/hypertrophy Genitourinary 1.09 0.932 – 1.26 0.294 187 1862 all phecode
586.4 Stricture/obstruction of ureter Genitourinary 0.955 0.909 – 1 0.0688 1821 17115 all phecode
587 Kidney replaced by transpant Genitourinary 0.951 0.884 – 1.02 0.178 819 8134 all phecode
588 Disorders resulting from impaired renal function Genitourinary 0.962 0.899 – 1.03 0.256 976 9389 all phecode
588.1 Renal osteodystrophy Genitourinary 1.05 0.934 – 1.19 0.398 290 2900 all phecode
588.2 Secondary hyperparathyroidism (of renal origin) Genitourinary 0.949 0.878 – 1.02 0.178 755 7275 all phecode
589 Abnormal results of function study of kidney Genitourinary 0.971 0.909 – 1.04 0.378 1007 9834 all phecode
590 Pyelonephritis Genitourinary 1.01 0.953 – 1.06 0.8 1461 14350 all phecode
591 Urinary tract infection Genitourinary 1 0.98 – 1.03 0.81 9873 32513 all phecode
592 Cystitis and urethritis Genitourinary 1.02 0.979 – 1.06 0.371 3038 24207 all phecode
592.1 Cystitis Genitourinary 1.02 0.979 – 1.06 0.367 2880 23279 all phecode
592.11 Acute cystitis Genitourinary 1.02 0.972 – 1.07 0.393 1783 16452 all phecode
592.12 Chronic cystitis Genitourinary 0.975 0.853 – 1.11 0.708 239 2343 all phecode
592.13 Chronic interstitial cystitis Genitourinary 0.972 0.879 – 1.08 0.589 431 4310 all phecode
592.2 Urethritis and urethral syndrome Genitourinary 1.07 0.925 – 1.24 0.359 210 2093 all phecode
593 Hematuria Genitourinary 1.02 0.992 – 1.06 0.151 4859 32063 all phecode
593.1 Gross hematuria Genitourinary 0.962 0.912 – 1.01 0.15 1585 14824 all phecode
593.2 Microscopic hematuria Genitourinary 1.03 0.963 – 1.1 0.416 1049 10301 all phecode
594 Urinary calculus Genitourinary 0.996 0.97 – 1.02 0.771 6707 38209 all phecode
594.1 Calculus of kidney Genitourinary 0.998 0.971 – 1.03 0.873 6273 38051 all phecode
594.2 Calculus of lower urinary tract Genitourinary 1.03 0.927 – 1.15 0.552 366 3638 all phecode
594.3 Calculus of ureter Genitourinary 0.976 0.922 – 1.03 0.394 1361 13561 all phecode
594.8 Renal colic Genitourinary 1.01 0.9 – 1.13 0.914 356 3560 all phecode
595 Hydronephrosis Genitourinary 0.969 0.92 – 1.02 0.227 1670 16658 all phecode
596 Other disorders of bladder Genitourinary 0.996 0.958 – 1.03 0.818 3074 28020 all phecode
596.1 Bladder neck obstruction Genitourinary 0.916 0.824 – 1.02 0.103 400 3942 all phecode
596.5 Functional disorders of bladder Genitourinary 1.01 0.964 – 1.07 0.602 1719 17049 all phecode
597 Other disorders of urethra and urinary tract Genitourinary 0.972 0.915 – 1.03 0.361 1211 11998 all phecode
597.1 Urethral stricture (not specified as infectious) Genitourinary 0.927 0.854 – 1.01 0.0706 661 6537 all phecode
597.2 Urinary complications NEC Genitourinary 0.964 0.904 – 1.03 0.272 1049 10479 all phecode
597.8 Urethral hypermobility/ISD Genitourinary 0.909 0.781 – 1.06 0.22 189 1873 all phecode
598 Abnormal findings on examination of urine Genitourinary 1.03 0.859 – 1.23 0.756 138 1356 all phecode
598.4 Other cells and casts in urine Genitourinary 1.03 0.854 – 1.25 0.73 122 1192 all phecode
599 Other symptoms/disorders or the urinary system Genitourinary 1 0.984 – 1.03 0.665 14168 30681 all phecode
599.1 Urinary obstruction Genitourinary 0.896 0.829 – 0.967 0.00503 728 6861 all phecode
599.2 Retention of urine Genitourinary 1 0.973 – 1.04 0.797 5034 28305 all phecode
599.3 Dysuria Genitourinary 1.01 0.976 – 1.04 0.598 4397 27849 all phecode
599.4 Urinary incontinence Genitourinary 1.01 0.977 – 1.04 0.644 5599 26960 all phecode
599.5 Frequency of urination and polyuria Genitourinary 1 0.973 – 1.03 0.854 5498 28723 all phecode
599.6 Oliguria and anuria Genitourinary 0.954 0.876 – 1.04 0.275 599 5902 all phecode
599.7 Urethral discharge Genitourinary 1.09 0.895 – 1.32 0.397 118 1175 all phecode
599.8 Other symptoms involving urinary system Genitourinary 1.01 0.984 – 1.05 0.35 5446 27963 all phecode
599.9 Other abnormality of urination Genitourinary 0.99 0.953 – 1.03 0.622 3041 24877 all phecode
600 Hyperplasia of prostate Genitourinary 0.989 0.951 – 1.03 0.562 4063 11364 all phecode
601 Inflammatory diseases of prostate Genitourinary 0.938 0.879 – 1 0.051 1044 9665 all phecode
601.1 Prostatitis Genitourinary 0.982 0.892 – 1.08 0.71 477 4596 all phecode
601.11 Acute prostatitis Genitourinary 1.09 0.891 – 1.32 0.417 124 1200 all phecode
601.12 Chronic prostatitis Genitourinary 1.01 0.814 – 1.25 0.945 95 943 all phecode
601.3 Orchitis and epididymitis Genitourinary 0.926 0.833 – 1.03 0.158 389 3822 all phecode
601.4 Balanoposthitis Genitourinary 0.784 0.652 – 0.943 0.00991 127 1224 all phecode
601.8
Other inflammatory disorders of male genital
Other inflammatory disorders of male genital organs
 Genitourinary 0.983 0.83 – 1.16 0.838 161 1591 all phecode
602 Other disorders of prostate Genitourinary 1.05 0.937 – 1.17 0.419 361 3399 all phecode
602.3 Dysplasia of prostate Genitourinary 1.05 0.824 – 1.35 0.675 77 730 all phecode
603 Other disorders of testis Genitourinary 0.921 0.834 – 1.02 0.102 440 4354 all phecode
603.1 Hydrocele Genitourinary 0.847 0.749 – 0.956 0.00746 293 2882 all phecode
603.2 Spermatocele Genitourinary 1.02 0.864 – 1.2 0.82 156 1539 all phecode
604 Disorders of penis Genitourinary 0.925 0.855 – 1 0.0524 685 6748 all phecode
604.1 Redundant prepuce and phimosis/BXO Genitourinary 1.03 0.865 – 1.21 0.775 155 1540 all phecode
604.3 Peyronie's disease Genitourinary 0.842 0.729 – 0.973 0.0195 215 2132 all phecode
605 Erectile dysfunction [ED] Genitourinary 0.981 0.945 – 1.02 0.33 3776 12700 all phecode
608 Other disorders of male genital organs Genitourinary 0.974 0.924 – 1.03 0.326 1645 13758 all phecode
609 Male infertility and abnormal spermatozoa Genitourinary 0.924 0.833 – 1.02 0.132 424 4196 all phecode
609.1 Infertility, male Genitourinary 0.904 0.8 – 1.02 0.106 302 2992 all phecode
609.11 Azoospermia and oligospermia Genitourinary 0.777 0.625 – 0.966 0.023 95 950 all phecode
609.2 Abnormal spermatozoa Genitourinary 1.06 0.891 – 1.25 0.529 154 1519 all phecode
610 Benign mammary dysplasias Genitourinary 1.01 0.975 – 1.05 0.536 3683 16548 all phecode
610.1 Cystic mastopathy Genitourinary 0.984 0.934 – 1.04 0.554 1633 14191 all phecode
610.2 Fibroadenosis of breast Genitourinary 0.863 0.655 – 1.14 0.297 60 600 all phecode
610.4 Benign neoplasm of breast Genitourinary 1.03 0.986 – 1.07 0.19 2837 16430 all phecode
610.8 Other specified benign mammary dysplasias Genitourinary 0.99 0.933 – 1.05 0.746 1269 12191 all phecode
611 Abnormal findings on mammogram or breast exam Genitourinary 1.03 0.999 – 1.06 0.0602 6067 18690 all phecode
611.1 Abnormal mammogram Genitourinary 1.02 0.99 – 1.06 0.174 4980 16120 all phecode
611.11 Mammographic microcalcification Genitourinary 1 0.939 – 1.07 0.99 1122 10394 all phecode
611.3 Lump or mass in breast Genitourinary 1.03 0.991 – 1.07 0.142 3549 18572 all phecode
612
Breast conditions, congenital or relating to
Breast conditions, congenital or relating to hormones
 Genitourinary 0.988 0.926 – 1.06 0.728 1051 10425 all phecode
612.1 Galactorrhea Genitourinary 1.11 0.922 – 1.33 0.276 139 1390 all phecode
612.2 Hypertrophy of breast (Gynecomastia) Genitourinary 0.979 0.909 – 1.05 0.576 800 7962 all phecode
612.3 Congenital anomalies of breast Genitourinary 0.833 0.657 – 1.06 0.133 83 810 all phecode
613 Other nonmalignant breast conditions Genitourinary 1 0.967 – 1.04 0.936 3897 22072 all phecode
613.1 Inflammatory disease of breast Genitourinary 0.951 0.871 – 1.04 0.254 593 5874 all phecode
613.5 Mastodynia Genitourinary 0.996 0.946 – 1.05 0.872 1675 16203 all phecode
613.7 Other signs and symptoms in breast Genitourinary 0.981 0.914 – 1.05 0.602 883 8754 all phecode
613.8 Other specified disorders of breast Genitourinary 0.999 0.932 – 1.07 0.986 932 9248 all phecode
613.9 Breast disorder NOS Genitourinary 0.997 0.943 – 1.05 0.909 1465 14174 all phecode
614 Inflammatory diseases of female pelvic organs Genitourinary 1.02 0.983 – 1.06 0.29 3715 19647 all phecode
614.1
Pelvic peritoneal adhesions, female
Pelvic peritoneal adhesions, female (postoperative) (postinfection)
 Genitourinary 0.974 0.867 – 1.09 0.655 337 3370 all phecode
614.3 Pelvic inflammatory disease (PID) Genitourinary 1.05 0.95 – 1.15 0.354 478 4773 all phecode
614.31 Acute inflammatory pelvic disease Genitourinary 1.09 0.874 – 1.36 0.438 94 933 all phecode
614.32 Chronic inflammatory pelvic disease Genitourinary 1.06 0.906 – 1.23 0.486 186 1842 all phecode
614.33 Pelvic inflammatory disease, NOS Genitourinary 1.03 0.897 – 1.17 0.706 246 2460 all phecode
614.4 Inflammatory diseases of uterus, except cervix Genitourinary 1.13 0.958 – 1.32 0.151 165 1639 all phecode
614.5
Inflammatory disease of cervix, vagina, and
Inflammatory disease of cervix, vagina, and vulva
 Genitourinary 1.02 0.982 – 1.06 0.293 3180 19539 all phecode
614.51 Cervicitis and endocervicitis Genitourinary 1.02 0.9 – 1.16 0.726 264 2640 all phecode
614.52 Vaginitis and vulvovaginitis Genitourinary 1.02 0.974 – 1.06 0.476 2732 18924 all phecode
614.53 Cyst or abscess of Bartholin's gland Genitourinary 0.975 0.807 – 1.18 0.788 132 1311 all phecode
614.54 Abscess or ulceration of vulva Genitourinary 0.981 0.853 – 1.13 0.791 225 2244 all phecode
615 Endometriosis Genitourinary 0.989 0.938 – 1.04 0.681 1585 14666 all phecode
618 Genital prolapse Genitourinary 1.01 0.967 – 1.06 0.596 2079 17915 all phecode
618.1 Prolapse of vaginal walls Genitourinary 1.01 0.956 – 1.07 0.708 1408 13456 all phecode
618.2 Uterine/Uterovaginal prolapse Genitourinary 0.99 0.906 – 1.08 0.822 542 5390 all phecode
618.5 Prolapse of vaginal vault after hysterectomy Genitourinary 1.13 1 – 1.27 0.0457 317 3162 all phecode
618.6 Vaginal enterocele, congenital or acquired Genitourinary 1.04 0.94 – 1.15 0.461 441 4394 all phecode
619 Noninflammatory female genital disorders Genitourinary 0.996 0.966 – 1.03 0.815 5728 18687 all phecode
619.1
Noninflammatory disorders of ovary, fallopian
Noninflammatory disorders of ovary, fallopian tube, and broad ligament
 Genitourinary 0.947 0.892 – 1.01 0.0793 1233 12082 all phecode
619.2 Disorders of uterus, NEC Genitourinary 1.01 0.926 – 1.1 0.832 591 5897 all phecode
619.3 Noninflammatory disorders of cervix Genitourinary 0.991 0.901 – 1.09 0.861 483 4823 all phecode
619.4 Noninflammatory disorders of vagina Genitourinary 0.99 0.948 – 1.03 0.649 2525 18404 all phecode
619.5 Noninflammatory disorders of vulva and perineum Genitourinary 1.03 0.972 – 1.1 0.292 1189 11717 all phecode
620 Dysplasia of female genital organs Genitourinary 0.978 0.88 – 1.09 0.677 395 3950 all phecode
620.1 Dysplasia of cervix Genitourinary 0.978 0.838 – 1.14 0.78 178 1780 all phecode
621 Endometrial hyperplasia Genitourinary 0.878 0.795 – 0.971 0.0112 437 4370 all phecode
622 Polyp of female genital organs Genitourinary 0.948 0.897 – 1 0.0582 1449 14264 all phecode
622.1 Polyp of corpus uteri Genitourinary 0.948 0.891 – 1.01 0.093 1132 11189 all phecode
622.2 Mucous polyp of cervix Genitourinary 0.902 0.816 – 0.996 0.0418 445 4444 all phecode
623 Hypertrophy of female genital organs Genitourinary 0.996 0.926 – 1.07 0.924 824 8165 all phecode
624 Symptoms involving female genital tract Genitourinary 0.988 0.933 – 1.05 0.688 1348 12518 all phecode
624.1 Dystrophy of female genital tract Genitourinary 1.05 0.908 – 1.21 0.509 216 2155 all phecode
624.2 Atrophy of female genital tract Genitourinary 0.943 0.733 – 1.21 0.646 64 615 all phecode
624.9 stress incontinence, female Genitourinary 1 0.957 – 1.05 0.847 1935 15408 all phecode
625
Pain and other symptoms associated with female
Pain and other symptoms associated with female genital organs
 Genitourinary 0.988 0.958 – 1.02 0.459 5653 17303 all phecode
625.1 Dyspareunia Genitourinary 1.01 0.951 – 1.07 0.746 1267 12474 all phecode
626
Disorders of menstruation and other abnormal
Disorders of menstruation and other abnormal bleeding from female genital tract
 Genitourinary 0.976 0.946 – 1.01 0.136 5940 15585 all phecode
626.1 Irregular menstrual cycle/bleeding Genitourinary 0.981 0.946 – 1.02 0.289 4315 14604 all phecode
626.11 Absent or infrequent menstruation Genitourinary 0.962 0.901 – 1.03 0.244 1062 8531 all phecode
626.12 Excessive or frequent menstruation Genitourinary 0.977 0.932 – 1.02 0.342 2097 11991 all phecode
626.13 Irregular menstrual cycle Genitourinary 0.984 0.937 – 1.03 0.531 1957 12265 all phecode
626.14 Irregular menstrual bleeding Genitourinary 0.942 0.88 – 1.01 0.0835 970 8996 all phecode
626.15 Infertility, female, associated with anovulation Genitourinary 0.959 0.862 – 1.07 0.448 394 3789 all phecode
626.2 Dysmenorrhea Genitourinary 0.993 0.937 – 1.05 0.81 1373 9857 all phecode
626.4 Premenstrual tension syndromes Genitourinary 0.958 0.855 – 1.07 0.454 336 3308 all phecode
626.8 Infertility, female Genitourinary 0.995 0.923 – 1.07 0.893 817 6741 all phecode
627 Menopausal and postmenopausal disorders Genitourinary 0.992 0.958 – 1.03 0.641 4560 14557 all phecode
627.1 Postmenopausal bleeding Genitourinary 0.954 0.896 – 1.02 0.138 1146 10338 all phecode
627.2 Symptomatic menopause Genitourinary 0.984 0.945 – 1.03 0.447 3017 13763 all phecode
627.21 Symptomatic artificial menopause Genitourinary 1.08 0.911 – 1.27 0.386 152 1514 all phecode
627.22
Need for Hormone replacement therapy
Need for Hormone replacement therapy (postmenopausal)
 Genitourinary 1.04 0.927 – 1.16 0.525 356 3513 all phecode
627.3 Postmenopausal atrophic vaginitis Genitourinary 0.977 0.914 – 1.04 0.503 997 9484 all phecode
627.4 Premenopausal menorrhagia Genitourinary 0.959 0.859 – 1.07 0.453 361 3580 all phecode
627.5 Premature menopause and other ovarian failure Genitourinary 0.951 0.843 – 1.07 0.409 309 3082 all phecode
628 Ovarian cyst Genitourinary 0.982 0.935 – 1.03 0.459 1945 13838 all phecode
634 Miscarriage; stillbirth Pregnancy Complications 0.993 0.923 – 1.07 0.862 826 8047 all phecode
634.1 Missed abortion/Hydatidiform mole Pregnancy Complications 1.02 0.901 – 1.16 0.714 273 2715 all phecode
634.3 Ectopic pregnancy Pregnancy Complications 0.955 0.79 – 1.15 0.636 117 1170 all phecode
635
Hemorrhage during pregnancy; childbirth and
Hemorrhage during pregnancy; childbirth and postpartum
 Pregnancy Complications 1.1 1.01 – 1.21 0.0341 563 5309 all phecode
635.2
Antepartum hemorrhage, abruptio placentae, and
Antepartum hemorrhage, abruptio placentae, and placenta previa
 Pregnancy Complications 1.09 0.977 – 1.22 0.123 370 3629 all phecode
635.3 Placenta previa and abruptio placenta Pregnancy Complications 1.01 0.894 – 1.14 0.872 288 2850 all phecode
636
Early or threatened labor; hemorrhage in early
Early or threatened labor; hemorrhage in early pregnancy
 Pregnancy Complications 0.997 0.934 – 1.06 0.934 1080 7870 all phecode
636.1 Threatened premature labor Pregnancy Complications 0.914 0.821 – 1.02 0.0962 380 3799 all phecode
636.2 Early onset of delivery Pregnancy Complications 0.884 0.783 – 0.999 0.0475 288 2868 all phecode
636.3 Hemorrhage in early pregnancy Pregnancy Complications 1.05 0.944 – 1.16 0.391 441 4365 all phecode
636.8 Cervical incompetence Pregnancy Complications 0.93 0.73 – 1.18 0.554 77 770 all phecode
637
Short gestation; low birth weight; and fetal
Short gestation; low birth weight; and fetal growth retardation
 Pregnancy Complications 1.02 0.809 – 1.28 0.879 85 850 all phecode
642
Hypertension complicating pregnancy
Hypertension complicating pregnancy, childbirth, and the puerperium
 Pregnancy Complications 1.04 0.949 – 1.13 0.436 585 5725 all phecode
642.1 Preeclampsia and eclampsia Pregnancy Complications 1.05 0.931 – 1.18 0.437 302 3013 all phecode
643 Excessive vomiting in pregnancy Pregnancy Complications 0.924 0.812 – 1.05 0.233 252 2506 all phecode
643.1 Hyperemesis gravidarum Pregnancy Complications 0.957 0.79 – 1.16 0.655 119 1190 all phecode
644 Anemia during pregnancy Pregnancy Complications 0.935 0.813 – 1.08 0.346 224 2224 all phecode
646 Other complications of pregnancy NEC Pregnancy Complications 0.998 0.927 – 1.07 0.963 855 6531 all phecode
647
Infectious and parasitic complications
Infectious and parasitic complications affecting pregnancy
 Pregnancy Complications 0.978 0.846 – 1.13 0.763 211 2093 all phecode
647.1
Infections of genitourinary tract during
Infections of genitourinary tract during pregnancy
 Pregnancy Complications 0.99 0.86 – 1.14 0.893 222 2213 all phecode
647.3 Major puerperal infection Pregnancy Complications 0.963 0.751 – 1.23 0.766 65 650 all phecode
649
Other conditions or status of the mother
Other conditions or status of the mother complicating pregnancy, childbirth, or the puerperium
 Pregnancy Complications 1.03 0.964 – 1.09 0.43 1275 8010 all phecode
649.1
Diabetes or abnormal glucose tolerance
Diabetes or abnormal glucose tolerance complicating pregnancy
 Pregnancy Complications 1.05 0.969 – 1.14 0.222 649 5687 all phecode
653
Problems associated with amniotic cavity and
Problems associated with amniotic cavity and membranes
 Pregnancy Complications 1.03 0.944 – 1.12 0.506 587 5463 all phecode
654.1
Abnormality of organs and soft tissues of
Abnormality of organs and soft tissues of pelvis complicating pregnancy, childbirth, or the puerperium
 Pregnancy Complications 1.1 0.949 – 1.28 0.202 207 2055 all phecode
654.2 Rhesus isoimmunization in pregnancy Pregnancy Complications 1.14 0.986 – 1.33 0.076 204 2040 all phecode
655
Known or suspected fetal abnormality affecting
Known or suspected fetal abnormality affecting management of mother
 Pregnancy Complications 1.05 0.991 – 1.1 0.105 1624 10064 all phecode
655.1 Abnormality in fetal heart rate or rhythm Pregnancy Complications 1.07 0.979 – 1.16 0.138 616 5533 all phecode
656 Other perinatal conditions of fetus or newborn Pregnancy Complications 0.993 0.925 – 1.07 0.854 898 7014 all phecode
656.2 Respiratory conditions of fetus and newborn Pregnancy Complications 0.804 0.621 – 1.04 0.0985 66 660 all phecode
669 Complications of labor and delivery NEC Pregnancy Complications 1.01 0.941 – 1.09 0.769 887 6802 all phecode
671
Venous/cerebrovascular complications embolism
Venous/cerebrovascular complications embolism in pregnancy and the puerperium
 Pregnancy Complications 0.933 0.812 – 1.07 0.321 236 2351 all phecode
674 Other complications of the puerperium NEC Pregnancy Complications 0.937 0.794 – 1.1 0.438 158 1580 all phecode
676
Other disorders of the breast associated with
Other disorders of the breast associated with childbirth and disorders of lactation
 Pregnancy Complications 0.936 0.799 – 1.1 0.412 184 1814 all phecode
681 Superficial cellulitis and abscess Dermatologic 0.985 0.958 – 1.01 0.264 6500 38394 all phecode
681.1 Cellulitis and abscess of fingers/toes Dermatologic 0.974 0.917 – 1.03 0.376 1256 11462 all phecode
681.2 Cellulitis and abscess of face/neck Dermatologic 0.99 0.927 – 1.06 0.771 1007 9981 all phecode
681.3 Cellulitis and abscess of arm/hand Dermatologic 0.967 0.924 – 1.01 0.157 2123 19952 all phecode
681.5 Cellulitis and abscess of leg, except foot Dermatologic 0.974 0.932 – 1.02 0.248 2252 20944 all phecode
681.6 Cellulitis and abscess of foot, toe Dermatologic 0.995 0.947 – 1.05 0.839 1820 16893 all phecode
681.7 Cellulitis and abscess of trunk Dermatologic 0.956 0.906 – 1.01 0.0955 1572 15588 all phecode
686
Other local infections of skin and subcutaneous
Other local infections of skin and subcutaneous tissue
 Dermatologic 0.983 0.941 – 1.03 0.458 2257 21750 all phecode
686.1 Carbuncle and furuncle Dermatologic 0.998 0.914 – 1.09 0.973 558 5504 all phecode
686.2 Impetigo Dermatologic 0.975 0.877 – 1.08 0.632 414 4117 all phecode
686.3 Pilonidal cyst Dermatologic 0.915 0.778 – 1.08 0.283 160 1594 all phecode
686.4 Pyogenic granuloma Dermatologic 0.821 0.696 – 0.97 0.02 158 1570 all phecode
686.5 Pyoderma Dermatologic 1.01 0.784 – 1.31 0.922 63 630 all phecode
687 Symptoms affecting skin Dermatologic 1.01 0.96 – 1.06 0.691 1690 16343 all phecode
687.1 Rash and other nonspecific skin eruption Dermatologic 1.01 0.982 – 1.04 0.533 7007 34623 all phecode
687.3 Changes in skin texture Dermatologic 0.992 0.896 – 1.1 0.88 415 4121 all phecode
687.4 Disturbance of skin sensation Dermatologic 1 0.976 – 1.03 0.834 6375 34216 all phecode
689 Disorder of skin and subcutaneous tissue NOS Dermatologic 1.01 0.982 – 1.03 0.623 9311 37335 all phecode
690 Erythematosquamous dermatosis Dermatologic 1 0.974 – 1.04 0.778 5184 31581 all phecode
690.1 Seborrheic dermatitis Dermatologic 1 0.974 – 1.04 0.781 5174 31553 all phecode
691 Congenital anomalies of skin Dermatologic 0.915 0.837 – 1 0.0512 541 5337 all phecode
691.3 Congenital pigmentary anomalies of skin Dermatologic 0.912 0.697 – 1.19 0.499 62 613 all phecode
694 Dyschromia and Vitiligo Dermatologic 0.992 0.944 – 1.04 0.734 1861 17936 all phecode
694.1 Vitiligo Dermatologic 0.893 0.752 – 1.06 0.196 137 1347 all phecode
694.2 Other dyschromia Dermatologic 0.983 0.934 – 1.03 0.503 1674 16183 all phecode
694.3 Vascular disorders of skin Dermatologic 1.32 1.03 – 1.68 0.0274 82 819 all phecode
695 Erythematous conditions Dermatologic 0.945 0.914 – 0.977 0.00095 4120 30247 all phecode
695.1 Toxic erythema Dermatologic 0.92 0.725 – 1.17 0.492 70 688 all phecode
695.2 Bullous dermatoses Dermatologic 1.08 0.853 – 1.37 0.515 85 805 all phecode
695.3 Rosacea Dermatologic 0.93 0.885 – 0.977 0.00391 1816 17663 all phecode
695.4 Lupus (localized and systemic) Dermatologic 0.932 0.859 – 1.01 0.089 672 6686 all phecode
695.41 Cutaneous lupus erythematosus Dermatologic 1.02 0.891 – 1.17 0.785 247 2437 all phecode
695.42 Systemic lupus erythematosus Dermatologic 0.919 0.845 – 1 0.0502 637 6337 all phecode
695.7 Prurigo and Lichen Dermatologic 0.961 0.883 – 1.05 0.358 605 5986 all phecode
695.8 Other specified erythematous conditions Dermatologic 0.881 0.819 – 0.948 0.000704 812 7980 all phecode
695.81 Erythema nodosum Dermatologic 0.859 0.656 – 1.12 0.269 55 550 all phecode
695.9 Unspecified erythematous condition Dermatologic 1.01 0.934 – 1.1 0.753 679 6756 all phecode
696 Psoriasis and related disorders Dermatologic 0.999 0.944 – 1.06 0.973 1401 13832 all phecode
696.3 Pityriasis Dermatologic 0.998 0.807 – 1.23 0.986 92 904 all phecode
696.4 Psoriasis Dermatologic 1 0.946 – 1.06 0.914 1311 12976 all phecode
696.41 Psoriasis vulgaris Dermatologic 0.994 0.935 – 1.06 0.843 1200 11867 all phecode
696.42 Psoriatic arthropathy Dermatologic 1.06 0.938 – 1.21 0.336 282 2810 all phecode
697 Sarcoidosis Dermatologic 0.944 0.843 – 1.06 0.324 333 3330 all phecode
698 Pruritus and related conditions Dermatologic 1 0.959 – 1.05 0.904 2254 21889 all phecode
700 Corns and callosities Dermatologic 0.962 0.908 – 1.02 0.189 1373 10894 all phecode
701
Other hypertrophic and atrophic conditions of
Other hypertrophic and atrophic conditions of skin
 Dermatologic 1.01 0.982 – 1.03 0.578 7651 38050 all phecode
701.1 Keratoderma, acquired Dermatologic 0.98 0.897 – 1.07 0.658 567 5524 all phecode
701.2 Scar conditions and fibrosis of skin Dermatologic 0.963 0.921 – 1.01 0.102 2184 21550 all phecode
701.3 Circumscribed scleroderma Dermatologic 1.02 0.934 – 1.11 0.654 571 5660 all phecode
701.4 Keloid scar Dermatologic 0.966 0.884 – 1.06 0.444 578 5716 all phecode
701.5 Abnormal granulation tissue Dermatologic 0.991 0.894 – 1.1 0.872 400 3982 all phecode
702
Degenerative skin conditions and other
Degenerative skin conditions and other dermatoses
 Dermatologic 1.01 0.987 – 1.04 0.318 6956 29525 all phecode
702.1 Actinic keratosis Dermatologic 1 0.967 – 1.03 1 4171 26529 all phecode
702.2 Seborrheic keratosis Dermatologic 1.02 0.987 – 1.05 0.275 5480 31552 all phecode
702.4 Degenerative skin disorders Dermatologic 1.19 0.952 – 1.48 0.128 86 832 all phecode
703 Diseases of nail, NOS Dermatologic 0.98 0.93 – 1.03 0.452 1650 14562 all phecode
703.1 Ingrowing nail Dermatologic 0.948 0.884 – 1.02 0.137 920 8597 all phecode
704 Diseases of hair and hair follicles Dermatologic 0.981 0.945 – 1.02 0.316 3118 29542 all phecode
704.1 Alopecia Dermatologic 0.988 0.934 – 1.05 0.68 1408 13871 all phecode
704.11 Alopecia Areata Dermatologic 1.15 0.899 – 1.46 0.273 82 811 all phecode
704.12 Telogen effluvium Dermatologic 0.946 0.724 – 1.24 0.684 63 615 all phecode
704.2 Hirsutism Dermatologic 1.03 0.908 – 1.16 0.677 299 2946 all phecode
704.8
Other specified diseases of hair and hair
Other specified diseases of hair and hair follicles
 Dermatologic 0.99 0.941 – 1.04 0.701 1752 17189 all phecode
705 Disorders of sweat glands Dermatologic 0.934 0.856 – 1.02 0.121 603 6012 all phecode
705.1 Dyshidrosis Dermatologic 0.908 0.768 – 1.07 0.26 154 1540 all phecode
705.3 Hidradenitis Dermatologic 0.955 0.832 – 1.09 0.507 245 2440 all phecode
705.8 Hyperhidrosis Dermatologic 1.02 0.953 – 1.08 0.624 1112 10986 all phecode
706 Diseases of sebaceous glands Dermatologic 0.993 0.966 – 1.02 0.631 5995 39748 all phecode
706.1 Acne Dermatologic 1 0.961 – 1.05 0.919 2594 22570 all phecode
706.2 Sebaceous cyst Dermatologic 0.994 0.955 – 1.03 0.767 2814 26819 all phecode
706.3 Seborrhea Dermatologic 1.16 0.878 – 1.52 0.302 59 582 all phecode
706.8 Other specified diseases of sebaceous glands Dermatologic 0.993 0.943 – 1.05 0.798 1684 15289 all phecode
707 Chronic ulcer of skin Dermatologic 0.984 0.946 – 1.02 0.414 2871 26816 all phecode
707.1 Decubitus ulcer Dermatologic 1.06 0.989 – 1.15 0.0946 825 8119 all phecode
707.2 Chronic ulcer of leg or foot Dermatologic 0.985 0.924 – 1.05 0.632 1108 9992 all phecode
707.3 Chronic ulcer of unspecified site Dermatologic 0.969 0.92 – 1.02 0.229 1641 16172 all phecode
709 Diffuse diseases of connective tissue Dermatologic 0.982 0.93 – 1.04 0.518 1477 14427 all phecode
709.2 Sicca syndrome Dermatologic 1.02 0.932 – 1.12 0.629 505 4986 all phecode
709.3 Systemic sclerosis Dermatologic 0.838 0.728 – 0.964 0.0135 224 2209 all phecode
709.5 Dermatomyositis Dermatologic 1.12 0.896 – 1.4 0.318 92 892 all phecode
709.6
Other specified diffuse diseases of connective
Other specified diffuse diseases of connective tissue
 Dermatologic 0.895 0.72 – 1.11 0.314 90 892 all phecode
709.7 Unspecified diffuse connective tissue disease Dermatologic 0.95 0.886 – 1.02 0.143 917 9089 all phecode
710
Osteomyelitis, periostitis, and other
Osteomyelitis, periostitis, and other infections involving bone
 Musculoskeletal 1.01 0.952 – 1.07 0.744 1254 12103 all phecode
710.1 Osteomyelitis Musculoskeletal 1.02 0.956 – 1.08 0.627 1203 11636 all phecode
710.11 Acute osteomyelitis Musculoskeletal 1.04 0.955 – 1.13 0.364 590 5708 all phecode
710.12 Chronic osteomyelitis Musculoskeletal 0.986 0.902 – 1.08 0.748 531 5163 all phecode
710.19 Unspecified osteomyelitis Musculoskeletal 1.01 0.946 – 1.07 0.855 1153 11149 all phecode
711 Arthropathy associated with infections Musculoskeletal 0.941 0.849 – 1.04 0.249 410 4099 all phecode
711.1 Pyogenic arthritis Musculoskeletal 0.964 0.853 – 1.09 0.551 290 2900 all phecode
712 Infective connective tissue disorders Musculoskeletal 0.909 0.781 – 1.06 0.219 178 1776 all phecode
713
Arthropathy associated with other disorders
Arthropathy associated with other disorders classified elsewhere
 Musculoskeletal 0.935 0.83 – 1.05 0.268 314 3028 all phecode
713.5
Arthropathy associated with neurological
Arthropathy associated with neurological disorders
 Musculoskeletal 0.956 0.824 – 1.11 0.551 194 1824 all phecode
714
Rheumatoid arthritis and other inflammatory
Rheumatoid arthritis and other inflammatory polyarthropathies
 Musculoskeletal 1 0.956 – 1.05 0.95 2086 18159 all phecode
714.1 Rheumatoid arthritis Musculoskeletal 0.996 0.946 – 1.05 0.878 1670 15087 all phecode
714.2 Juvenile rheumatoid arthritis Musculoskeletal 1.07 0.847 – 1.35 0.57 77 767 all phecode
715 Other inflammatory spondylopathies Musculoskeletal 0.96 0.903 – 1.02 0.183 1209 11967 all phecode
715.1 Sacroiliitis NEC Musculoskeletal 0.996 0.876 – 1.13 0.956 262 2611 all phecode
715.2 Ankylosing spondylitis Musculoskeletal 0.88 0.765 – 1.01 0.0725 219 2182 all phecode
716 Other arthropathies Musculoskeletal 0.985 0.964 – 1.01 0.173 13482 31305 all phecode
716.1 Unspecified polyarthropathy or polyarthritis Musculoskeletal 1.05 0.902 – 1.22 0.532 192 1920 all phecode
716.2 Unspecified monoarthritis Musculoskeletal 0.988 0.826 – 1.18 0.892 131 1293 all phecode
716.9 Arthropathy NOS Musculoskeletal 0.985 0.964 – 1.01 0.171 13410 31294 all phecode
717 Polymyalgia Rheumatica Musculoskeletal 1.11 0.971 – 1.27 0.128 261 2565 all phecode
720 Spinal stenosis Musculoskeletal 0.998 0.965 – 1.03 0.931 3958 28539 all phecode
720.1 Spinal stenosis of lumbar region Musculoskeletal 0.997 0.958 – 1.04 0.866 2872 23656 all phecode
721 Spondylosis and allied disorders Musculoskeletal 0.992 0.963 – 1.02 0.574 5509 32391 all phecode
721.1 Spondylosis without myelopathy Musculoskeletal 0.989 0.959 – 1.02 0.475 5153 31896 all phecode
721.2 Spondylosis with myelopathy Musculoskeletal 0.991 0.923 – 1.06 0.8 867 8629 all phecode
721.8 Other allied disorders of spine Musculoskeletal 0.896 0.788 – 1.02 0.0959 262 2600 all phecode
722 Intervertebral disc disorders Musculoskeletal 0.988 0.961 – 1.02 0.393 6284 34317 all phecode
722.1 Displacement of intervertebral disc Musculoskeletal 1 0.966 – 1.04 0.965 3591 31411 all phecode
722.3 Schmorl's nodes Musculoskeletal 0.967 0.803 – 1.16 0.719 126 1248 all phecode
722.6 Degeneration of intervertebral disc Musculoskeletal 0.985 0.952 – 1.02 0.37 3957 30744 all phecode
722.7 Intervertebral disc disorder with myelopathy Musculoskeletal 0.983 0.895 – 1.08 0.715 515 5140 all phecode
722.8 Postlaminectomy syndrome Musculoskeletal 1.08 0.974 – 1.21 0.141 397 3968 all phecode
722.9 Other and unspecified disc disorder Musculoskeletal 0.984 0.938 – 1.03 0.499 1932 19288 all phecode
723 Other disorders of cervical region Musculoskeletal 0.998 0.932 – 1.07 0.952 952 9495 all phecode
723.1 Torticollis Musculoskeletal 1.13 0.989 – 1.29 0.0726 254 2522 all phecode
724 Other and unspecified disorders of back Musculoskeletal 0.99 0.958 – 1.02 0.57 4130 31954 all phecode
724.1 Disorders of sacrum Musculoskeletal 1.01 0.964 – 1.05 0.752 2307 21902 all phecode
724.2 Disorders of coccyx Musculoskeletal 0.986 0.89 – 1.09 0.779 426 4215 all phecode
724.8 Other symptoms referable to back Musculoskeletal 0.949 0.886 – 1.02 0.138 931 9295 all phecode
724.9 Other unspecified back disorders Musculoskeletal 1.01 0.953 – 1.07 0.767 1412 14087 all phecode
726 Peripheral enthesopathies and allied syndromes Musculoskeletal 0.999 0.976 – 1.02 0.96 9917 30176 all phecode
726.1 Enthesopathy Musculoskeletal 1.01 0.98 – 1.03 0.639 7507 30106 all phecode
726.2 Synoviopathy Musculoskeletal 0.957 0.896 – 1.02 0.188 1015 9987 all phecode
726.3 Bursitis Musculoskeletal 0.973 0.926 – 1.02 0.281 1829 16722 all phecode
726.4 Calcaneal spur; Exostosis NOS Musculoskeletal 0.955 0.898 – 1.01 0.134 1193 11485 all phecode
727 Other disorders of synovium, tendon, and bursa Musculoskeletal 0.99 0.964 – 1.02 0.452 7425 30105 all phecode
727.1 Synovitis and tenosynovitis Musculoskeletal 0.996 0.958 – 1.03 0.833 3092 24998 all phecode
727.2 Bursitis disorders Musculoskeletal 0.931 0.838 – 1.03 0.18 419 4112 all phecode
727.4 Ganglion and cyst of synovium, tendon, and bursa Musculoskeletal 0.991 0.937 – 1.05 0.751 1400 13621 all phecode
727.5 Rupture of synovium Musculoskeletal 0.981 0.889 – 1.08 0.694 480 4672 all phecode
727.6 Rupture of tendon, nontraumatic Musculoskeletal 1 0.959 – 1.05 0.951 2461 21948 all phecode
727.7 Contracture of tendon (sheath) Musculoskeletal 0.97 0.89 – 1.06 0.486 591 5893 all phecode
727.8 Plica syndrome Musculoskeletal 0.954 0.791 – 1.15 0.619 130 1264 all phecode
728 Disorders of muscle, ligament, and fascia Musculoskeletal 0.986 0.955 – 1.02 0.393 4546 29473 all phecode
728.1 Muscular calcification and ossification Musculoskeletal 1.08 0.861 – 1.35 0.506 85 843 all phecode
728.2 Laxity of ligament or hypermobility syndrome Musculoskeletal 1.03 0.91 – 1.17 0.646 297 2949 all phecode
728.7 Fasciitis Musculoskeletal 0.975 0.936 – 1.01 0.21 2814 23463 all phecode
728.71
Contracture of palmar fascia [Dupuytren's
Contracture of palmar fascia [Dupuytren's disease]
 Musculoskeletal 0.97 0.876 – 1.07 0.553 419 4138 all phecode
729 Other disorders of soft tissues Musculoskeletal 0.978 0.944 – 1.01 0.225 3642 27471 all phecode
729.1 Rheumatism, unspecified and fibrositis Musculoskeletal 0.888 0.699 – 1.13 0.334 74 726 all phecode
729.3 Panniculitis Musculoskeletal 1.04 0.857 – 1.27 0.683 119 1174 all phecode
729.7 Nontraumatic compartment syndrome Musculoskeletal 0.962 0.745 – 1.24 0.769 67 664 all phecode
731
Osteitis deformans and osteopathies associated
Osteitis deformans and osteopathies associated with other disorders classified elsewhere
 Musculoskeletal 0.869 0.75 – 1.01 0.0601 210 2091 all phecode
732 Osteochondropathies Musculoskeletal 1.01 0.907 – 1.13 0.838 361 3604 all phecode
732.1 Juvenile osteochondrosis Musculoskeletal 0.939 0.809 – 1.09 0.409 198 1969 all phecode
732.7 Osteochondritis dissecans Musculoskeletal 0.995 0.8 – 1.24 0.965 90 882 all phecode
733 Other disorders of bone and cartilage Musculoskeletal 1 0.967 – 1.03 0.99 4543 26941 all phecode
733.2 Cyst of bone Musculoskeletal 1.06 0.906 – 1.23 0.48 190 1900 all phecode
733.4 Aseptic necrosis of bone Musculoskeletal 0.972 0.886 – 1.07 0.55 518 5160 all phecode
733.6 Costochondritis Musculoskeletal 0.956 0.855 – 1.07 0.433 357 3562 all phecode
733.8 Malunion and nonunion of fracture Musculoskeletal 0.977 0.908 – 1.05 0.524 822 8205 all phecode
733.9 Chondromalacia Musculoskeletal 1.11 0.9 – 1.37 0.329 96 960 all phecode
735 Acquired foot deformities Musculoskeletal 0.987 0.951 – 1.02 0.469 3417 29622 all phecode
735.1 Flat foot Musculoskeletal 1.03 0.949 – 1.13 0.445 620 6092 all phecode
735.2 Acquired toe deformities Musculoskeletal 1.02 0.962 – 1.08 0.503 1323 11983 all phecode
735.21 Hammer toe (acquired) Musculoskeletal 0.981 0.912 – 1.06 0.61 825 7494 all phecode
735.23 Hallux rigidus Musculoskeletal 1.13 1.02 – 1.26 0.0248 405 4005 all phecode
735.3 Hallux valgus (Bunion) Musculoskeletal 0.962 0.911 – 1.02 0.171 1470 14295 all phecode
736 Other acquired deformities of limbs Musculoskeletal 0.976 0.937 – 1.02 0.233 2763 26555 all phecode
736.1 Acquired deformities of forearm Musculoskeletal 0.973 0.793 – 1.2 0.797 104 1033 all phecode
736.2 Acquired deformities of finger Musculoskeletal 1.07 0.926 – 1.24 0.353 215 2142 all phecode
736.3 Acquired deformities of hip Musculoskeletal 0.863 0.662 – 1.13 0.28 60 590 all phecode
736.4 Genu valgum or varum (acquired) Musculoskeletal 0.955 0.851 – 1.07 0.436 325 3247 all phecode
736.5 Acquired deformities of knee Musculoskeletal 0.947 0.829 – 1.08 0.429 246 2460 all phecode
736.6 Unequal leg length (acquired) Musculoskeletal 0.997 0.891 – 1.12 0.965 339 3365 all phecode
737 Curvature of spine Musculoskeletal 0.965 0.915 – 1.02 0.186 1566 15543 all phecode
737.1 Kyphosis (acquired) Musculoskeletal 0.979 0.892 – 1.07 0.658 479 4748 all phecode
737.2 Lordosis (acquired) Musculoskeletal 1.01 0.8 – 1.29 0.905 70 700 all phecode
737.3 Kyphoscoliosis and scoliosis Musculoskeletal 0.961 0.904 – 1.02 0.201 1203 11982 all phecode
738 Other acquired musculoskeletal deformity Musculoskeletal 0.973 0.933 – 1.02 0.216 2443 24187 all phecode
738.4 Acquired spondylolisthesis Musculoskeletal 0.979 0.917 – 1.04 0.512 1057 10542 all phecode
739 Contracture of joint Musculoskeletal 0.928 0.852 – 1.01 0.085 621 6207 all phecode
740 Osteoarthrosis Musculoskeletal 0.995 0.975 – 1.02 0.644 16169 30268 all phecode
740.1 Osteoarthritis; localized Musculoskeletal 0.995 0.968 – 1.02 0.705 7005 27422 all phecode
740.11 Osteoarthrosis, localized, primary Musculoskeletal 0.995 0.967 – 1.02 0.735 6176 26155 all phecode
740.12 Osteoarthrosis, localized, secondary Musculoskeletal 0.944 0.872 – 1.02 0.154 713 7116 all phecode
740.2 Osteoarthrosis, generalized Musculoskeletal 1.02 0.969 – 1.08 0.409 1609 12092 all phecode
740.3
Osteoarthrosis involving more than one site
Osteoarthrosis involving more than one site, but not specified as generalized
 Musculoskeletal 1 0.897 – 1.11 0.997 373 3586 all phecode
740.9 Osteoarthrosis NOS Musculoskeletal 0.995 0.974 – 1.02 0.617 15497 30141 all phecode
741 Symptoms and disorders of the joints Musculoskeletal 1.01 0.99 – 1.04 0.259 8555 35884 all phecode
741.1 Ankylosis of joint Musculoskeletal 1.08 0.939 – 1.24 0.289 245 2445 all phecode
741.2 Stiffness of joint Musculoskeletal 1.02 0.959 – 1.08 0.549 1268 12594 all phecode
741.3 Difficulty in walking Musculoskeletal 1.01 0.967 – 1.05 0.69 2558 23116 all phecode
741.4 Joint effusions Musculoskeletal 1.04 0.992 – 1.08 0.111 2493 24199 all phecode
741.5 Hemarthrosis Musculoskeletal 1.31 1.05 – 1.63 0.0159 94 937 all phecode
741.6 Villonodular synovitis Musculoskeletal 0.973 0.759 – 1.25 0.827 68 666 all phecode
742 Derangement of joint, non-traumatic Musculoskeletal 1.01 0.974 – 1.04 0.708 4404 33771 all phecode
742.1 Loose body in joint Musculoskeletal 1.27 1.07 – 1.51 0.00616 156 1554 all phecode
742.2
Pathological, developmental or recurrent
Pathological, developmental or recurrent dislocation
 Musculoskeletal 0.997 0.881 – 1.13 0.962 280 2792 all phecode
742.8 Articular cartilage disorder Musculoskeletal 1.07 0.936 – 1.23 0.316 245 2450 all phecode
742.9 Other derangement of joint Musculoskeletal 1 0.969 – 1.04 0.905 4107 32972 all phecode
743
Osteoporosis, osteopenia and pathological
Osteoporosis, osteopenia and pathological fracture
 Musculoskeletal 0.997 0.973 – 1.02 0.825 9223 36921 all phecode
743.1 Osteoporosis Musculoskeletal 0.993 0.956 – 1.03 0.698 3712 19477 all phecode
743.11 Osteoporosis NOS Musculoskeletal 0.995 0.959 – 1.03 0.807 3657 19276 all phecode
743.12 Senile osteoporosis Musculoskeletal 1.06 0.98 – 1.15 0.142 703 5804 all phecode
743.13 Other specified osteoporosis Musculoskeletal 0.937 0.833 – 1.05 0.283 321 3141 all phecode
743.2 Pathologic fracture Musculoskeletal 1.03 0.962 – 1.09 0.435 1112 10563 all phecode
743.21 Pathologic fracture of vertebrae Musculoskeletal 1.03 0.936 – 1.13 0.537 475 4629 all phecode
743.22 Pathologic fracture of femur Musculoskeletal 0.992 0.826 – 1.19 0.928 143 1391 all phecode
743.4 Stress fracture Musculoskeletal 1.07 0.963 – 1.19 0.21 407 4046 all phecode
743.9
Osteopenia or other disorder of bone and
Osteopenia or other disorder of bone and cartilage
 Musculoskeletal 1 0.973 – 1.03 0.998 6970 35237 all phecode
745 Pain in joint Musculoskeletal 0.997 0.978 – 1.02 0.753 19848 26918 all phecode
747 Cardiac and circulatory congenital anomalies Congenital Anomalies 0.999 0.955 – 1.04 0.964 2236 22256 all phecode
747.1 Cardiac congenital anomalies Congenital Anomalies 0.993 0.945 – 1.04 0.793 1767 17598 all phecode
747.11 Cardiac shunt/ heart septal defect Congenital Anomalies 0.947 0.871 – 1.03 0.195 650 6497 all phecode
747.12 Valvular heart disease/ heart chambers Congenital Anomalies 1.02 0.944 – 1.1 0.64 751 7480 all phecode
747.13 Congenital anomalies of great vessels Congenital Anomalies 1.02 0.923 – 1.13 0.67 410 4090 all phecode
747.2
Congenital anomalies of peripheral vascular
Congenital anomalies of peripheral vascular system
 Congenital Anomalies 1.02 0.934 – 1.12 0.606 501 5010 all phecode
748 Anomalies of respiratory system, congenital Congenital Anomalies 0.904 0.738 – 1.11 0.331 111 1110 all phecode
749 Congenital anomalies of face and neck Congenital Anomalies 0.931 0.852 – 1.02 0.118 555 5549 all phecode
749.1 Cleft palate Congenital Anomalies 1.05 0.84 – 1.3 0.686 97 970 all phecode
749.2 Congenital anomalies of skull and face bones Congenital Anomalies 1.03 0.839 – 1.26 0.79 105 1041 all phecode
750 Digestive congenital anomalies Congenital Anomalies 0.97 0.905 – 1.04 0.396 893 8919 all phecode
750.1 Upper gastrointestinal congenital anomalies Congenital Anomalies 1.02 0.914 – 1.14 0.741 366 3655 all phecode
750.11 Esophageal atresia/tracheoesophageal fistula Congenital Anomalies 1.11 0.917 – 1.35 0.282 119 1185 all phecode
750.13 Congenital anomalies of mouth/tongue Congenital Anomalies 0.894 0.73 – 1.09 0.275 99 982 all phecode
750.14 Congenital anomalies of esophagus Congenital Anomalies 1.16 0.967 – 1.39 0.11 134 1332 all phecode
750.15 Congenital anomalies of stomach Congenital Anomalies 0.959 0.73 – 1.26 0.762 60 593 all phecode
750.2 Lower gastrointestinal congenital anomalies Congenital Anomalies 0.935 0.854 – 1.02 0.144 531 5300 all phecode
750.21 Congenital anomalies of intestine Congenital Anomalies 0.991 0.88 – 1.12 0.883 313 3129 all phecode
750.22
Congenital anomaly of gallbladder, bile ducts
Congenital anomaly of gallbladder, bile ducts, liver, pancreas
 Congenital Anomalies 0.881 0.767 – 1.01 0.0722 222 2214 all phecode
751 Genitourinary congenital anomalies Congenital Anomalies 0.985 0.94 – 1.03 0.531 2008 19975 all phecode
751.1 Congenital anomalies of genital organs Congenital Anomalies 1.08 0.985 – 1.17 0.103 574 5740 all phecode
751.11 Congenital anomalies of female genital organs Congenital Anomalies 1.1 0.985 – 1.22 0.0923 384 3840 all phecode
751.12 Congenital anomalies of male genital organs Congenital Anomalies 1.07 0.905 – 1.27 0.421 153 1527 all phecode
751.2 Congenital anomalies of urinary system Congenital Anomalies 0.961 0.908 – 1.02 0.164 1379 13704 all phecode
751.21 Cystic kidney disease Congenital Anomalies 0.955 0.893 – 1.02 0.178 976 9685 all phecode
751.22 Other specified congenital anomalies of kidney Congenital Anomalies 0.966 0.856 – 1.09 0.579 294 2927 all phecode
751.3 Obstructive genitourinary defect Congenital Anomalies 0.991 0.849 – 1.16 0.905 182 1809 all phecode
752 Nervous system congenital anomalies Congenital Anomalies 0.983 0.923 – 1.05 0.583 1133 11313 all phecode
752.1 Neural tube defects Congenital Anomalies 0.97 0.905 – 1.04 0.401 923 9209 all phecode
752.11 Spina bifida Congenital Anomalies 1.01 0.864 – 1.18 0.885 176 1760 all phecode
752.2
Other specified congenital anomalies of nervous
Other specified congenital anomalies of nervous system
 Congenital Anomalies 1.03 0.898 – 1.18 0.67 232 2320 all phecode
753 Congenital anomalies of the eye Congenital Anomalies 1.06 0.915 – 1.22 0.442 207 2051 all phecode
753.1 Congenital cataract and lens anomalies Congenital Anomalies 1.21 0.922 – 1.59 0.17 58 580 all phecode
753.2 Congenital anomalies of posterior segment of eye Congenital Anomalies 1.09 0.823 – 1.45 0.537 56 546 all phecode
754 Congenital musculoskeletal deformities of spine Congenital Anomalies 0.962 0.905 – 1.02 0.205 1216 12116 all phecode
754.1 Lumbosacral spondylolysis, congenital Congenital Anomalies 1 0.826 – 1.21 0.999 135 1333 all phecode
754.2 Spondylolisthesis, congenital Congenital Anomalies 0.959 0.877 – 1.05 0.357 558 5570 all phecode
755 Congenital anomalies of limbs Congenital Anomalies 0.986 0.913 – 1.07 0.73 747 7458 all phecode
755.1 Congenital deformities of feet Congenital Anomalies 0.981 0.88 – 1.09 0.73 368 3663 all phecode
755.4
Congenital anomalies of upper limb, including
Congenital anomalies of upper limb, including shoulder girdle
 Congenital Anomalies 1.07 0.831 – 1.37 0.614 74 740 all phecode
755.6
Other congenital anomalies of lower limb
Other congenital anomalies of lower limb, including pelvic girdle
 Congenital Anomalies 0.961 0.854 – 1.08 0.518 321 3205 all phecode
755.61 Congenital hip dysplasia and deformity Congenital Anomalies 0.979 0.839 – 1.14 0.783 185 1847 all phecode
756 Other congenital musculoskeletal anomalies Congenital Anomalies 0.971 0.917 – 1.03 0.321 1358 13579 all phecode
756.1 Congenital anomalies of abdominal wall; diaphram Congenital Anomalies 0.894 0.69 – 1.16 0.394 68 680 all phecode
756.2
Pectus and other congenital anomalies of
Pectus and other congenital anomalies of ribs/sternum
 Congenital Anomalies 0.927 0.723 – 1.19 0.549 71 694 all phecode
756.3
Congenital anomalies of muscle, tendon, fascia
Congenital anomalies of muscle, tendon, fascia, and connective tissue
 Congenital Anomalies 0.982 0.878 – 1.1 0.747 335 3346 all phecode
756.5 Congenital osteodystrophies Congenital Anomalies 0.996 0.931 – 1.07 0.912 1003 10014 all phecode
757 Congenital anomalies of the integument Congenital Anomalies 1.01 0.906 – 1.12 0.911 401 4001 all phecode
758 Chromosomal anomalies and genetic disorders Congenital Anomalies 1.01 0.865 – 1.17 0.921 185 1845 all phecode
758.1 Chromosomal anomalies Congenital Anomalies 1.03 0.864 – 1.23 0.737 135 1349 all phecode
759 Other and unspecified congenital anomalies Congenital Anomalies 0.98 0.897 – 1.07 0.661 557 5566 all phecode
759.1 Anomalies of endocrine glands, congenital Congenital Anomalies 0.885 0.692 – 1.13 0.328 71 710 all phecode
760 Back pain Symptoms 1 0.984 – 1.02 0.708 16037 30719 all phecode
761 Cervicalgia Symptoms 0.994 0.968 – 1.02 0.678 6528 39755 all phecode
763
Thoracic or lumbosacral neuritis or
Thoracic or lumbosacral neuritis or radiculitis, unspecified
 Symptoms 0.98 0.946 – 1.01 0.255 3657 32599 all phecode
764 Sciatica Symptoms 0.996 0.961 – 1.03 0.822 3542 32015 all phecode
765 Cervical radiculitis Symptoms 0.992 0.944 – 1.04 0.739 1799 17851 all phecode
766 Neuralgia, neuritis, and radiculitis NOS Symptoms 0.975 0.947 – 1 0.102 5124 37132 all phecode
767 Cervicocranial/Cervicobrachial syndrome Symptoms 1.06 0.875 – 1.28 0.559 117 1168 all phecode
769 Nonallopathic lesions NEC Symptoms 0.995 0.934 – 1.06 0.874 1131 11220 all phecode
770 Myalgia and myositis unspecified Symptoms 0.991 0.963 – 1.02 0.559 5533 34303 all phecode
771 Musculoskeletal symptoms referable to limbs Symptoms 0.973 0.943 – 1 0.0849 4799 35575 all phecode
771.1 Swelling of limb Symptoms 0.965 0.938 – 0.993 0.015 5743 35539 all phecode
771.2 Cramp of limb Symptoms 1 0.938 – 1.07 0.987 1079 10568 all phecode
772 Symptoms of the muscles Symptoms 0.946 0.903 – 0.991 0.0191 2042 20221 all phecode
772.1 Muscular wasting and disuse atrophy Symptoms 1.01 0.914 – 1.12 0.799 422 4199 all phecode
772.2 Spasm of muscle Symptoms 0.962 0.92 – 1 0.0793 2299 22726 all phecode
772.3 Muscle weakness Symptoms 0.998 0.96 – 1.04 0.922 2949 28064 all phecode
772.4 Rhabdomyolysis Symptoms 1.11 0.942 – 1.32 0.207 159 1572 all phecode
772.6 Facial weakness Symptoms 0.986 0.894 – 1.09 0.776 478 4742 all phecode
780 Hypothermia/Chills Symptoms 1.03 0.928 – 1.13 0.622 453 4514 all phecode
781
Symptoms involving nervous and musculoskeletal
Symptoms involving nervous and musculoskeletal systems
 Symptoms 0.993 0.954 – 1.03 0.72 2822 26225 all phecode
781.1 Loss of height Symptoms 1.02 0.851 – 1.22 0.828 130 1269 all phecode
781.2 Abnormal posture Symptoms 1.02 0.78 – 1.34 0.873 57 567 all phecode
782.3 Edema Symptoms 0.99 0.963 – 1.02 0.502 5874 36788 all phecode
782.6 Pallor and flushing Symptoms 1.02 0.956 – 1.1 0.496 927 9252 all phecode
783 Fever of unknown origin Symptoms 1.01 0.981 – 1.04 0.535 5733 40720 all phecode
783.1 Postprocedural fever Symptoms 0.918 0.814 – 1.03 0.161 300 2992 all phecode
785 Abdominal pain Symptoms 0.985 0.966 – 1 0.128 16458 30297 all phecode
788 Syncope and collapse Symptoms 1.01 0.975 – 1.04 0.634 3851 35832 all phecode
789 Nausea and vomiting Symptoms 1 0.981 – 1.03 0.77 10568 36098 all phecode
789.1 Persistent vomiting Symptoms 0.966 0.897 – 1.04 0.361 798 7924 all phecode
790 Nonspecific findings on examination of blood Symptoms 0.999 0.957 – 1.04 0.981 2363 22690 all phecode
790.1 Elevated sedimentation rate Symptoms 1.11 0.97 – 1.28 0.125 236 2322 all phecode
790.6 Other abnormal blood chemistry Symptoms 1.01 0.983 – 1.03 0.533 7539 37788 all phecode
790.8 Elevated C-reactive protein (CRP) Symptoms 1.03 0.913 – 1.16 0.644 309 3075 all phecode
790.9 Abnormal arterial blood gases Symptoms 0.949 0.805 – 1.12 0.538 155 1521 all phecode
791 Gangrene Symptoms 0.975 0.866 – 1.1 0.677 313 3115 all phecode
792
Abnormal Papanicolaou smear of cervix and
Abnormal Papanicolaou smear of cervix and cervical HPV
 Genitourinary 1.01 0.974 – 1.06 0.486 2820 14872 all phecode
792.1
Papanicolaou smear of cervix or vagina with
Papanicolaou smear of cervix or vagina with atypical squamous cells
 Genitourinary 1.02 0.959 – 1.09 0.499 1100 9861 all phecode
794
Abnormal results of other function studies
Abnormal results of other function studies (bladder, pancreas, placenta, spleen, etc)
 Symptoms 1.05 0.952 – 1.15 0.353 515 5133 all phecode
795
Other and nonspecific abnormal cytological
Other and nonspecific abnormal cytological, histological and immunological findings
 Symptoms 0.989 0.945 – 1.03 0.631 2182 20242 all phecode
795.8 Abnormal tumor markers Symptoms 0.99 0.941 – 1.04 0.698 1745 15551 all phecode
795.81 Elevated carcinoembryonic antigen [CEA] Symptoms 0.878 0.681 – 1.13 0.318 61 605 all phecode
795.82 Elevated cancer antigen 125 [CA 125] Symptoms 0.997 0.86 – 1.16 0.967 201 2000 all phecode
796 Elevated prostate specific antigen [PSA] Genitourinary 0.997 0.95 – 1.05 0.904 2125 9930 all phecode
797 Shock Symptoms 1.03 0.944 – 1.12 0.53 605 6050 all phecode
797.1 Cardiogenic shock Symptoms 1.03 0.904 – 1.19 0.62 242 2420 all phecode
798 Malaise and fatigue Symptoms 1.01 0.992 – 1.04 0.223 11539 35196 all phecode
798.1 Chronic fatigue syndrome Symptoms 1 0.954 – 1.05 0.912 1823 17795 all phecode
800 Fracture of lower limb Injuries & Poisonings 1 0.959 – 1.05 0.957 2344 22951 all phecode
800.1 Fracture of neck of femur Injuries & Poisonings 1 0.915 – 1.1 0.947 512 4961 all phecode
800.2 Fracture of unspecified part of femur Injuries & Poisonings 1.02 0.945 – 1.11 0.554 670 6582 all phecode
800.3 Fracture of tibia and fibula Injuries & Poisonings 0.968 0.902 – 1.04 0.37 898 8966 all phecode
800.4 Fracture of patella Injuries & Poisonings 0.994 0.89 – 1.11 0.918 346 3456 all phecode
801 Fracture of ankle and foot Injuries & Poisonings 1.01 0.966 – 1.05 0.69 2358 22645 all phecode
801.1 Fracture of foot Injuries & Poisonings 0.999 0.939 – 1.06 0.986 1120 11178 all phecode
802 Fracture of pelvis Injuries & Poisonings 1.08 0.965 – 1.2 0.186 380 3765 all phecode
803 Fracture of upper limb Injuries & Poisonings 0.985 0.94 – 1.03 0.521 2051 20360 all phecode
803.1 Fracture of humerus Injuries & Poisonings 0.994 0.919 – 1.08 0.884 734 7322 all phecode
803.2 Fracture of radius and ulna Injuries & Poisonings 0.996 0.935 – 1.06 0.913 1112 11075 all phecode
803.21 Colles' fracture Injuries & Poisonings 1.02 0.903 – 1.16 0.737 291 2904 all phecode
803.3 Fracture of clavicle or scapula Injuries & Poisonings 0.911 0.831 – 1 0.0501 514 5140 all phecode
804 Fracture of hand or wrist Injuries & Poisonings 1.01 0.959 – 1.07 0.672 1628 16042 all phecode
805
Fracture of vertebral column without mention of
Fracture of vertebral column without mention of spinal cord injury
 Injuries & Poisonings 1.02 0.959 – 1.08 0.596 1336 13242 all phecode
807 Fracture of ribs Injuries & Poisonings 0.982 0.906 – 1.06 0.65 683 6815 all phecode
809 Fracture of unspecified bones Injuries & Poisonings 0.983 0.945 – 1.02 0.383 2941 28633 all phecode
816 Cerebral laceration and contusion Injuries & Poisonings 0.82 0.619 – 1.09 0.166 54 531 all phecode
817 Concussion Injuries & Poisonings 1 0.936 – 1.07 0.996 1018 10149 all phecode
818 Intracranial hemorrhage (injury) Injuries & Poisonings 0.93 0.826 – 1.05 0.228 311 3104 all phecode
818.1 Subdural hemorrhage (injury) Injuries & Poisonings 0.91 0.73 – 1.13 0.403 90 895 all phecode
818.2 Subarachnoid hemorrhage (injury) Injuries & Poisonings 1.06 0.859 – 1.31 0.583 97 970 all phecode
819
Skull and face fracture and other intercranial
Skull and face fracture and other intercranial injury
 Injuries & Poisonings 0.977 0.935 – 1.02 0.307 2287 22671 all phecode
830 Dislocation Injuries & Poisonings 1 0.97 – 1.04 0.833 3862 34720 all phecode
835 Internal derangement of knee Injuries & Poisonings 1.01 0.965 – 1.06 0.691 2231 21628 all phecode
836 Traumatic arthropathy Injuries & Poisonings 0.954 0.868 – 1.05 0.331 496 4954 all phecode
840 Sprains and strains Injuries & Poisonings 1 0.977 – 1.03 0.873 7838 37998 all phecode
840.1 Muscle/tendon sprain Injuries & Poisonings 1.03 0.943 – 1.13 0.483 537 5356 all phecode
840.2 Rotator cuff (capsule) sprain Injuries & Poisonings 0.985 0.935 – 1.04 0.576 1640 16263 all phecode
840.3 Joint/ligament sprain Injuries & Poisonings 0.993 0.955 – 1.03 0.741 2875 24879 all phecode
841 Sprains and strains of back and neck Injuries & Poisonings 0.965 0.916 – 1.02 0.192 1583 15592 all phecode
842 Other sprains and strains Injuries & Poisonings 0.978 0.924 – 1.04 0.44 1407 13924 all phecode
850 Hemorrhage or hematoma complicating a procedure Injuries & Poisonings 0.967 0.923 – 1.01 0.153 2072 20649 all phecode
851
Complications of transplants and reattached
Complications of transplants and reattached limbs
 Injuries & Poisonings 0.977 0.94 – 1.02 0.238 2982 27545 all phecode
853 Complication of colostomy or enterostomy Injuries & Poisonings 1.03 0.93 – 1.13 0.605 460 4600 all phecode
854
Complications of cardiac/vascular device
Complications of cardiac/vascular device, implant, and graft
 Injuries & Poisonings 1.02 0.969 – 1.06 0.528 1985 19675 all phecode
855
Complication of nervous system device, implant
Complication of nervous system device, implant, and graft
 Injuries & Poisonings 0.967 0.848 – 1.1 0.613 264 2640 all phecode
856
Vascular complications of surgery and medical
Vascular complications of surgery and medical procedures
 Injuries & Poisonings 0.987 0.874 – 1.11 0.825 293 2929 all phecode
857
Mechanical complication of unspecified
Mechanical complication of unspecified genitourinary device, implant, and graft
 Injuries & Poisonings 0.95 0.896 – 1.01 0.0831 1310 13087 all phecode
858 Complication of internal orthopedic device Injuries & Poisonings 0.988 0.945 – 1.03 0.594 2213 21944 all phecode
859
Complication due to other implant and internal
Complication due to other implant and internal device
 Injuries & Poisonings 0.967 0.923 – 1.01 0.146 2110 21070 all phecode
860 Bone marrow or stem cell transplant Neoplasms 0.946 0.805 – 1.11 0.499 166 1660 all phecode
870 Open wounds of head; neck; and trunk Injuries & Poisonings 0.979 0.947 – 1.01 0.21 4117 36734 all phecode
870.1 Open wound or laceration of eye or eyelid Injuries & Poisonings 0.942 0.815 – 1.09 0.426 204 2026 all phecode
870.2 Open wound of ear Injuries & Poisonings 1.01 0.854 – 1.2 0.874 144 1437 all phecode
870.3 Other open wound of head and face Injuries & Poisonings 0.956 0.903 – 1.01 0.118 1346 13301 all phecode
870.4 Open wound of nose and sinus Injuries & Poisonings 1.06 0.917 – 1.23 0.424 207 2057 all phecode
870.5 Open wound of lip and mouth Injuries & Poisonings 0.993 0.874 – 1.13 0.917 275 2724 all phecode
870.6 Open wound of neck Injuries & Poisonings 0.993 0.861 – 1.15 0.922 214 2128 all phecode
870.8 Open wound of genital organs Injuries & Poisonings 1.07 0.898 – 1.27 0.46 144 1440 all phecode
871 Open wounds of extremities Injuries & Poisonings 1 0.968 – 1.04 0.876 3530 32903 all phecode
871.1 Open wound of hand except finger(s) Injuries & Poisonings 0.988 0.904 – 1.08 0.794 572 5701 all phecode
871.2 Open wound of finger(s) Injuries & Poisonings 1.02 0.955 – 1.09 0.529 984 9772 all phecode
871.3 Open wound of foot except toe(s) alone Injuries & Poisonings 0.973 0.885 – 1.07 0.573 490 4843 all phecode
871.4 Open wound of toe(s) Injuries & Poisonings 1.02 0.908 – 1.15 0.705 295 2921 all phecode
872 Traumatic amputation Injuries & Poisonings 1.06 0.972 – 1.16 0.179 551 5477 all phecode
874 Complication of amputation stump Injuries & Poisonings 0.982 0.836 – 1.15 0.823 170 1697 all phecode
875 Non-healing surgical wound Injuries & Poisonings 0.948 0.867 – 1.04 0.246 572 5720 all phecode
876
Posttraumatic wound infection not elsewhere
Posttraumatic wound infection not elsewhere classified
 Injuries & Poisonings 1.01 0.935 – 1.09 0.843 802 8003 all phecode
907 Injuries to the nervous system Injuries & Poisonings 1.1 1.03 – 1.17 0.00658 1010 10096 all phecode
910 Superficial injury, infected Injuries & Poisonings 0.973 0.797 – 1.19 0.79 119 1161 all phecode
911 Blister Injuries & Poisonings 0.901 0.798 – 1.02 0.0916 302 2996 all phecode
912 Insect bite Injuries & Poisonings 0.941 0.857 – 1.03 0.207 492 4886 all phecode
913 Toxic effect of venom Injuries & Poisonings 0.911 0.813 – 1.02 0.106 337 3326 all phecode
916 Contusion Injuries & Poisonings 0.997 0.965 – 1.03 0.836 4296 38033 all phecode
930 Allergic reaction to food Injuries & Poisonings 0.975 0.904 – 1.05 0.52 763 7596 all phecode
931
Contact dermatitis and other eczema due to
Contact dermatitis and other eczema due to plants [except food]
 Dermatologic 1.01 0.934 – 1.09 0.792 714 7072 all phecode
938 Dermatitis due to solar radiation Dermatologic 1.01 0.982 – 1.04 0.437 5567 29098 all phecode
938.1 Acute dermatitis due to solar radiation Dermatologic 1.08 0.938 – 1.25 0.279 217 2164 all phecode
938.2 Chronic dermatitis due to solar radiation Dermatologic 1.01 0.978 – 1.04 0.615 5307 28656 all phecode
939
Atopic/contact dermatitis due to other or
Atopic/contact dermatitis due to other or unspecified
 Dermatologic 1 0.973 – 1.03 0.993 6704 32389 all phecode
939.1 Contact and allergic dermatitis of eyelid Dermatologic 0.915 0.734 – 1.14 0.43 91 870 all phecode
941 Adverse reaction to serum or vaccine Injuries & Poisonings 1.04 0.893 – 1.21 0.613 188 1880 all phecode
942 Infusion and transfusion reaction Injuries & Poisonings 1.04 0.918 – 1.19 0.515 269 2688 all phecode
946 Anaphylactic shock NOS Injuries & Poisonings 0.975 0.887 – 1.07 0.605 500 4940 all phecode
947 Urticaria Dermatologic 0.999 0.939 – 1.06 0.98 1177 11454 all phecode
949 Allergies, other Injuries & Poisonings 1 0.975 – 1.03 0.942 7251 32350 all phecode
952
Spinal cord injury without evidence of spinal
Spinal cord injury without evidence of spinal bone injury
 Injuries & Poisonings 1.07 0.97 – 1.18 0.176 494 4940 all phecode
957 Injury to other and unspecified nerves Injuries & Poisonings 1.06 0.886 – 1.28 0.506 136 1352 all phecode
958
Certain early complications of trauma or
Certain early complications of trauma or procedure
 Injuries & Poisonings 0.989 0.931 – 1.05 0.721 1217 12158 all phecode
958.1 Postoperative shock Injuries & Poisonings 1.12 0.954 – 1.32 0.164 169 1688 all phecode
958.2 Traumatic and surgical subcutaneous emphysema Injuries & Poisonings 1.1 0.906 – 1.34 0.329 114 1140 all phecode
960 Poisoning by antibiotics Injuries & Poisonings 0.962 0.922 – 1 0.0721 2479 22087 all phecode
960.1
Adverse effects of antibacterials (not
Adverse effects of antibacterials (not penicillins)
 Injuries & Poisonings 1.01 0.904 – 1.13 0.849 342 3403 all phecode
960.2 Allergy/adverse effect of penicillin Injuries & Poisonings 0.96 0.911 – 1.01 0.121 1636 16005 all phecode
961 Poisoning by other anti-infectives Injuries & Poisonings 1.02 0.927 – 1.12 0.709 528 5234 all phecode
961.1 Poisoning/allergy of sulfonamides Injuries & Poisonings 0.964 0.904 – 1.03 0.259 1065 10347 all phecode
962 Poisoning by hormones and synthetic substitutes Injuries & Poisonings 0.975 0.905 – 1.05 0.509 803 7976 all phecode
962.1
Adrenal cortical steroids causing adverse
Adrenal cortical steroids causing adverse effects in therapeutic use
 Injuries & Poisonings 0.973 0.873 – 1.09 0.629 379 3782 all phecode
962.2
Insulins and antidiabetic agents causing
Insulins and antidiabetic agents causing adverse effects in therapeutic use
 Injuries & Poisonings 0.819 0.633 – 1.06 0.126 62 612 all phecode
962.3
Hormones and synthetic substitutes causing
Hormones and synthetic substitutes causing adverse effects in therapeutic use
 Injuries & Poisonings 0.972 0.883 – 1.07 0.558 478 4773 all phecode
963 Poisoning by primarily systemic agents Injuries & Poisonings 1.01 0.964 – 1.05 0.799 2533 24531 all phecode
963.1
Antineoplastic and immunosuppressive drugs
Antineoplastic and immunosuppressive drugs causing adverse effects
 Injuries & Poisonings 1.02 0.973 – 1.06 0.489 2469 24057 all phecode
964
Poisoning by agents primarily affecting blood
Poisoning by agents primarily affecting blood constituents
 Injuries & Poisonings 0.977 0.905 – 1.06 0.558 743 7337 all phecode
964.1 Anticoagulants causing adverse effects Injuries & Poisonings 0.968 0.896 – 1.05 0.419 712 7027 all phecode
965
Poisoning by analgesics, antipyretics, and
Poisoning by analgesics, antipyretics, and antirheumatics
 Injuries & Poisonings 1.04 0.965 – 1.12 0.319 864 8601 all phecode
965.1
Opiates and related narcotics causing adverse
Opiates and related narcotics causing adverse effects in therapeutic use
 Injuries & Poisonings 1.02 0.963 – 1.08 0.53 1469 14402 all phecode
965.3
Salicylates causing adverse effects in
Salicylates causing adverse effects in therapeutic use
 Injuries & Poisonings 1.17 0.968 – 1.41 0.106 119 1182 all phecode
966
Poisoning by anticonvulsants and
Poisoning by anticonvulsants and anti-Parkinsonism drugs
 Injuries & Poisonings 0.94 0.767 – 1.15 0.546 103 1006 all phecode
967
Adverse effects of sedatives or other central
Adverse effects of sedatives or other central nervous system depressants and anesthetics
 Injuries & Poisonings 0.971 0.915 – 1.03 0.339 1254 12464 all phecode
969 Poisoning by psychotropic agents Injuries & Poisonings 1.07 0.947 – 1.22 0.272 281 2797 all phecode
971
Poisoning by drugs primarily affecting the
Poisoning by drugs primarily affecting the autonomic nervous system
 Injuries & Poisonings 1.01 0.779 – 1.31 0.933 67 643 all phecode
972
Poisoning by agents primarily affecting the
Poisoning by agents primarily affecting the cardiovascular system
 Injuries & Poisonings 1.02 0.905 – 1.16 0.703 288 2858 all phecode
972.1
Cardiac rhythm regulators causing adverse
Cardiac rhythm regulators causing adverse effects in therapeutic use
 Injuries & Poisonings 1.02 0.81 – 1.29 0.852 80 776 all phecode
972.6 Antihypertensive agents causing adverse effects Injuries & Poisonings 0.939 0.765 – 1.15 0.547 104 1034 all phecode
974
Poisoning by water, mineral, and uric acid
Poisoning by water, mineral, and uric acid metabolism drugs
 Injuries & Poisonings 1.1 0.9 – 1.34 0.355 113 1130 all phecode
975
Poisoning by agents primarily acting on the
Poisoning by agents primarily acting on the smooth and skeletal muscles and respiratory system
 Injuries & Poisonings 1 0.793 – 1.27 0.977 81 810 all phecode
976
Poisoning by agents primarily affecting skin &
Poisoning by agents primarily affecting skin & mucous membrane, ophthalmological, otorhinolaryngological, & dental drugs
 Injuries & Poisonings 1.31 1.02 – 1.69 0.0376 71 703 all phecode
977 Personal history of allergy to medicinal agents Injuries & Poisonings 0.947 0.901 – 0.996 0.0347 1763 16599 all phecode
979 Adverse drug events and drug allergies Injuries & Poisonings 1 0.966 – 1.04 0.939 3448 30885 all phecode
980
Encounter for long-term (current) use of
Encounter for long-term (current) use of antibiotics
 Infectious Diseases 0.979 0.925 – 1.04 0.459 1391 13877 all phecode
985 Toxic effect of other metals Injuries & Poisonings 1.4 1.06 – 1.86 0.0197 57 564 all phecode
989
Toxic effect of other substances, chiefly
Toxic effect of other substances, chiefly nonmedicinal as to source
 Injuries & Poisonings 1.01 0.838 – 1.22 0.92 129 1275 all phecode
990 Effects radiation NOS Injuries & Poisonings 1.01 0.975 – 1.04 0.631 3927 31223 all phecode
994 Sepsis and SIRS Injuries & Poisonings 0.993 0.95 – 1.04 0.76 2192 21710 all phecode
994.1 Systemic inflammatory response syndrome (SIRS) Injuries & Poisonings 0.951 0.841 – 1.07 0.42 291 2910 all phecode
994.2 Sepsis Injuries & Poisonings 0.995 0.951 – 1.04 0.829 2086 20666 all phecode
994.21 Septic shock Injuries & Poisonings 0.974 0.896 – 1.06 0.538 627 6260 all phecode
008 Intestinal infection Infectious Diseases 1.01 0.953 – 1.06 0.813 1654 8261 exclusion phecode
008.5 Bacterial enteritis Infectious Diseases 1.05 0.96 – 1.14 0.299 639 3592 exclusion phecode
008.52 Intestinal infection due to C. difficile Infectious Diseases 1.1 0.992 – 1.21 0.0712 491 2797 exclusion phecode
008.6 Viral Enteritis Infectious Diseases 0.952 0.861 – 1.05 0.34 497 2241 exclusion phecode
010 Tuberculosis Infectious Diseases 1.07 0.874 – 1.32 0.501 115 647 exclusion phecode
031 Diseases due to other mycobacteria Infectious Diseases 0.835 0.605 – 1.15 0.273 50 237 exclusion phecode
038 Septicemia Infectious Diseases 1.07 1.01 – 1.14 0.0268 1306 6576 exclusion phecode
038.1 Gram negative septicemia Infectious Diseases 0.996 0.883 – 1.12 0.948 327 1595 exclusion phecode
038.2 Gram positive septicemia Infectious Diseases 0.95 0.776 – 1.16 0.622 128 667 exclusion phecode
038.3 Bacteremia Infectious Diseases 1.06 0.971 – 1.15 0.204 688 3322 exclusion phecode
041 Bacterial infection NOS Infectious Diseases 1.05 1 – 1.1 0.0296 2589 10038 exclusion phecode
041.1 Staphylococcus infections Infectious Diseases 1.04 0.963 – 1.13 0.304 731 4485 exclusion phecode
041.11 Methicillin sensitive Staphylococcus aureus Infectious Diseases 1.04 0.939 – 1.16 0.436 441 2521 exclusion phecode
041.12 Methicillin resistant Staphylococcus aureus Infectious Diseases 1.03 0.91 – 1.16 0.649 310 2056 exclusion phecode
041.2 Streptococcus infection Infectious Diseases 1.06 0.977 – 1.14 0.166 791 4330 exclusion phecode
041.21 Rheumatic fever / chorea Infectious Diseases 1.18 0.959 – 1.45 0.118 101 677 exclusion phecode
041.4 E. coli Infectious Diseases 1.08 0.988 – 1.18 0.0887 593 3055 exclusion phecode
041.8 H. pylori Infectious Diseases 0.846 0.694 – 1.03 0.0966 126 719 exclusion phecode
041.9 Infection with drug-resistant microorganisms Infectious Diseases 1.13 0.966 – 1.32 0.127 202 991 exclusion phecode
053 Herpes zoster Infectious Diseases 0.986 0.913 – 1.06 0.72 872 3648 exclusion phecode
053.1 Herpes zoster with nervous system complications Infectious Diseases 0.968 0.791 – 1.18 0.751 120 505 exclusion phecode
054 Herpes simplex Infectious Diseases 0.982 0.908 – 1.06 0.641 808 3508 exclusion phecode
070 Viral hepatitis Infectious Diseases 1.02 0.909 – 1.14 0.763 373 1902 exclusion phecode
070.1 Viral hepatitis A Infectious Diseases 1.07 0.743 – 1.53 0.727 37 207 exclusion phecode
070.2 Viral hepatitis B Infectious Diseases 0.92 0.735 – 1.15 0.465 95 459 exclusion phecode
070.3 Viral hepatitis C Infectious Diseases 1.01 0.88 – 1.17 0.863 240 1192 exclusion phecode
070.4 Chronic hepatitis Infectious Diseases 1.06 0.862 – 1.31 0.565 112 463 exclusion phecode
070.9 Hepatitis NOS Infectious Diseases 0.994 0.901 – 1.1 0.905 489 2588 exclusion phecode
071 Human immunodeficiency virus [HIV] disease Infectious Diseases 1.49 1.15 – 1.92 0.00227 90 364 exclusion phecode
071.1 HIV infection, symptomatic Infectious Diseases 1.59 1.19 – 2.12 0.0016 77 277 exclusion phecode
078 Viral warts & HPV Infectious Diseases 0.991 0.94 – 1.04 0.731 1886 6345 exclusion phecode
079 Viral infection Infectious Diseases 1.02 0.983 – 1.07 0.267 3758 7576 exclusion phecode
079.1 Varicella infection Infectious Diseases 1.02 0.966 – 1.07 0.536 2086 6866 exclusion phecode
079.2 Infectious mononucleosis Infectious Diseases 1.09 0.88 – 1.35 0.433 115 547 exclusion phecode
079.9 Viremia, NOS Infectious Diseases 1.09 0.987 – 1.2 0.0897 555 1926 exclusion phecode
080 Postoperative infection Infectious Diseases 0.98 0.914 – 1.05 0.571 950 7033 exclusion phecode
081
Infection/inflammation of internal prosthetic
Infection/inflammation of internal prosthetic device; implant; and graft
 Infectious Diseases 1.01 0.926 – 1.1 0.874 652 4237 exclusion phecode
090
Sexually transmitted infections (not HIV or
Sexually transmitted infections (not HIV or hepatitis)
 Infectious Diseases 1.08 0.977 – 1.18 0.138 492 2956 exclusion phecode
110 Dermatophytosis / Dermatomycosis Infectious Diseases 1.02 0.972 – 1.07 0.436 2370 7636 exclusion phecode
110.1 Dermatophytosis Infectious Diseases 1.02 0.967 – 1.07 0.536 2222 7019 exclusion phecode
110.11 Dermatophytosis of nail Infectious Diseases 1.01 0.953 – 1.07 0.698 1478 4721 exclusion phecode
110.12 Althete's foot Infectious Diseases 1.05 0.956 – 1.14 0.327 643 2512 exclusion phecode
110.13 Dermatophytosis of the body Infectious Diseases 1.03 0.934 – 1.14 0.538 510 2201 exclusion phecode
110.2 Dermatomycoses Infectious Diseases 0.997 0.856 – 1.16 0.965 215 1062 exclusion phecode
112 Candidiasis Infectious Diseases 1.05 0.995 – 1.11 0.0762 1791 7237 exclusion phecode
112.3 Candidiasis of skin and nails Infectious Diseases 0.977 0.874 – 1.09 0.683 377 1665 exclusion phecode
117 Mycoses Infectious Diseases 1.01 0.885 – 1.15 0.909 286 1512 exclusion phecode
117.1 Histoplasmosis Infectious Diseases 1.14 0.769 – 1.68 0.519 31 211 exclusion phecode
117.4 Aspergillosis Infectious Diseases 1.27 0.982 – 1.64 0.0681 73 360 exclusion phecode
130 Spirochetal infection Infectious Diseases 0.972 0.774 – 1.22 0.81 88 433 exclusion phecode
130.1 Lyme disease Infectious Diseases 1.13 0.852 – 1.5 0.396 59 292 exclusion phecode
131 Protozoan infection Infectious Diseases 0.998 0.65 – 1.53 0.993 29 149 exclusion phecode
132 Infestation (lice, mites) Infectious Diseases 0.861 0.702 – 1.06 0.149 110 569 exclusion phecode
134 Helminthiases Infectious Diseases 0.923 0.659 – 1.29 0.643 40 208 exclusion phecode
134.1 Intestinal helminthiases Infectious Diseases 0.918 0.586 – 1.44 0.709 26 158 exclusion phecode
136 Other infectious and parasitic diseases Infectious Diseases 1.03 0.975 – 1.09 0.285 1495 8894 exclusion phecode
145 Cancer of mouth Neoplasms 0.897 0.786 – 1.02 0.106 237 4174 exclusion phecode
145.1 Cancer of lip Neoplasms 0.695 0.407 – 1.19 0.182 13 193 exclusion phecode
145.2 Cancer of tongue Neoplasms 0.915 0.74 – 1.13 0.41 97 1815 exclusion phecode
145.3 Cancer of major salivary glands Neoplasms 1.05 0.806 – 1.35 0.739 64 1022 exclusion phecode
145.4 Cancer of the gums Neoplasms 0.683 0.428 – 1.09 0.109 18 443 exclusion phecode
145.5 Cancer of the mouth floor Neoplasms 1.02 0.69 – 1.49 0.937 24 555 exclusion phecode
149 Cancer of larynx, pharynx, nasal cavities Neoplasms 0.804 0.701 – 0.922 0.00175 214 3722 exclusion phecode
149.1 Cancer of oropharynx Neoplasms 0.883 0.693 – 1.13 0.316 71 1031 exclusion phecode
149.2 Cancer of nasopharynx Neoplasms 0.739 0.502 – 1.09 0.125 23 280 exclusion phecode
149.3 Cancer of hypopharynx Neoplasms 1.04 0.628 – 1.73 0.872 12 249 exclusion phecode
149.4 Cancer of larynx Neoplasms 0.729 0.563 – 0.945 0.017 59 1103 exclusion phecode
149.5
Hx of malignant neoplasm of oral cavity and
Hx of malignant neoplasm of oral cavity and pharynx
 Neoplasms 0.786 0.654 – 0.944 0.0101 117 1562 exclusion phecode
149.9 Cancer of of nasal cavities Neoplasms 1.05 0.739 – 1.48 0.802 30 677 exclusion phecode
150 Cancer of esophagus Neoplasms 1.01 0.813 – 1.25 0.946 89 1153 exclusion phecode
151 Cancer of stomach Neoplasms 1.01 0.824 – 1.23 0.946 109 1331 exclusion phecode
153 Colorectal cancer Neoplasms 1.01 0.912 – 1.11 0.902 478 2916 exclusion phecode
153.2 Colon cancer Neoplasms 1.01 0.907 – 1.13 0.824 379 2317 exclusion phecode
153.3
Malignant neoplasm of rectum, rectosigmoid
Malignant neoplasm of rectum, rectosigmoid junction, and anus
 Neoplasms 0.965 0.847 – 1.1 0.591 266 1626 exclusion phecode
155 Cancer of liver and intrahepatic bile duct Neoplasms 1.15 0.959 – 1.37 0.134 146 1273 exclusion phecode
155.1 Malignant neoplasm of liver, primary Neoplasms 1.19 0.961 – 1.47 0.112 107 886 exclusion phecode
157 Pancreatic cancer Neoplasms 0.911 0.761 – 1.09 0.31 124 1314 exclusion phecode
158
Neoplasm of unspecified nature of digestive
Neoplasm of unspecified nature of digestive system
 Neoplasms 0.935 0.86 – 1.02 0.109 680 4186 exclusion phecode
159
Malignant neoplasm of other and ill-defined
Malignant neoplasm of other and ill-defined sites within the digestive organs and peritoneum
 Neoplasms 0.979 0.897 – 1.07 0.643 567 4491 exclusion phecode
159.2
Malignant neoplasm of small intestine
Malignant neoplasm of small intestine, including duodenum
 Neoplasms 1 0.76 – 1.32 1 54 578 exclusion phecode
159.3
Malignant neoplasm of gallbladder and
Malignant neoplasm of gallbladder and extrahepatic bile ducts
 Neoplasms 0.913 0.621 – 1.34 0.644 27 445 exclusion phecode
159.4
Malignant neoplasm of retroperitoneum and
Malignant neoplasm of retroperitoneum and peritoneum
 Neoplasms 0.931 0.738 – 1.17 0.548 76 675 exclusion phecode
164 Cancer of intrathoracic organs Neoplasms 1.06 0.778 – 1.44 0.716 38 388 exclusion phecode
165 Cancer within the respiratory system Neoplasms 0.94 0.841 – 1.05 0.282 343 3762 exclusion phecode
165.1 Cancer of bronchus; lung Neoplasms 0.941 0.834 – 1.06 0.319 298 2976 exclusion phecode
170 Cancer of bone and connective tissue Neoplasms 0.962 0.855 – 1.08 0.516 303 4875 exclusion phecode
170.1 Bone cancer Neoplasms 0.923 0.775 – 1.1 0.373 134 2065 exclusion phecode
170.2 Cancer of connective tissue Neoplasms 0.956 0.831 – 1.1 0.532 210 3403 exclusion phecode
172 Skin cancer Neoplasms 0.988 0.942 – 1.04 0.605 2528 9210 exclusion phecode
172.1 Melanomas of skin, dx or hx Neoplasms 0.984 0.931 – 1.04 0.565 1674 8341 exclusion phecode
172.11 Melanomas of skin Neoplasms 0.953 0.873 – 1.04 0.276 567 6825 exclusion phecode
172.2 Other non-epithelial cancer of skin Neoplasms 0.987 0.94 – 1.04 0.604 2278 8549 exclusion phecode
172.21 Basal cell carcinoma Neoplasms 1.02 0.959 – 1.08 0.548 1423 6781 exclusion phecode
172.22 Squamous cell carcinoma Neoplasms 1.02 0.942 – 1.1 0.669 819 5106 exclusion phecode
172.3 Carcinoma in situ of skin Neoplasms 1.04 0.949 – 1.13 0.419 594 3724 exclusion phecode
173 Neoplasm of uncertain behavior of skin Neoplasms 0.984 0.918 – 1.05 0.643 988 5557 exclusion phecode
174 Breast cancer Neoplasms 1 0.931 – 1.08 0.902 908 3559 exclusion phecode
174.1 Breast cancer [female] Neoplasms 1.02 0.94 – 1.1 0.665 851 3303 exclusion phecode
174.11 Malignant neoplasm of female breast Neoplasms 1.03 0.947 – 1.11 0.526 833 3269 exclusion phecode
174.3 Neoplasm of uncertain behavior of breast Neoplasms 1.08 0.868 – 1.34 0.494 90 521 exclusion phecode
175 Acquired absence of breast Neoplasms 1.04 0.909 – 1.19 0.556 256 1546 exclusion phecode
180 Cervical cancer and dysplasia Neoplasms 1.04 0.939 – 1.14 0.484 515 2553 exclusion phecode
180.1 Cervical cancer Neoplasms 0.954 0.788 – 1.15 0.628 114 956 exclusion phecode
180.3
Cervical intraepithelial neoplasia [CIN]
Cervical intraepithelial neoplasia [CIN] [Cervical dysplasia]
 Neoplasms 1.03 0.927 – 1.15 0.555 442 1936 exclusion phecode
182 Malignant neoplasm of uterus Neoplasms 0.932 0.797 – 1.09 0.379 182 1609 exclusion phecode
184 Cancer of other female genital organs Neoplasms 0.967 0.864 – 1.08 0.554 346 2752 exclusion phecode
184.1
Malignant neoplasm of ovary and other uterine
Malignant neoplasm of ovary and other uterine adnexa
 Neoplasms 0.889 0.746 – 1.06 0.193 139 1358 exclusion phecode
184.11 Malignant neoplasm of ovary Neoplasms 0.897 0.734 – 1.1 0.29 103 1025 exclusion phecode
184.2
Cancer of other female genital organs
Cancer of other female genital organs (excluding uterus and ovary)
 Neoplasms 1 0.866 – 1.16 0.985 210 1465 exclusion phecode
185 Cancer of prostate Neoplasms 0.923 0.846 – 1.01 0.0689 748 2820 exclusion phecode
187 Cancer of other male genital organs Neoplasms 1.04 0.856 – 1.27 0.675 109 1020 exclusion phecode
187.1
Malignant neoplasm of unspecified male genital
Malignant neoplasm of unspecified male genital organ
 Neoplasms 1.12 0.756 – 1.65 0.577 31 366 exclusion phecode
187.2 Malignant neoplasm of testis Neoplasms 0.997 0.752 – 1.32 0.984 55 509 exclusion phecode
187.8
Neoplasm of uncertain behavior of male genital
Neoplasm of uncertain behavior of male genital organs
 Neoplasms 0.998 0.684 – 1.46 0.992 31 181 exclusion phecode
189
Cancer of urinary organs (incl. kidney and
Cancer of urinary organs (incl. kidney and bladder)
 Neoplasms 1.02 0.948 – 1.11 0.544 741 6823 exclusion phecode
189.1 Cancer of kidney and renal pelvis Neoplasms 0.938 0.841 – 1.05 0.256 354 4251 exclusion phecode
189.11 Malignant neoplasm of kidney, except pelvis Neoplasms 0.94 0.832 – 1.06 0.314 295 3717 exclusion phecode
189.12 Malignant neoplasm of renal pelvis Neoplasms 0.918 0.714 – 1.18 0.5 66 728 exclusion phecode
189.2 Cancer of bladder Neoplasms 1.09 0.991 – 1.21 0.0745 462 4574 exclusion phecode
189.21 Malignant neoplasm of bladder Neoplasms 1.04 0.94 – 1.16 0.423 405 4274 exclusion phecode
189.4 Malignant neoplasm of other urinary organs Neoplasms 1.14 0.969 – 1.34 0.115 167 1978 exclusion phecode
190 Cancer of eye Neoplasms 0.789 0.56 – 1.11 0.175 35 389 exclusion phecode
191
Manlignant and unknown neoplasms of brain and
Manlignant and unknown neoplasms of brain and nervous system
 Neoplasms 0.976 0.851 – 1.12 0.723 225 2763 exclusion phecode
191.1 Cancer of brain and nervous system Neoplasms 0.933 0.785 – 1.11 0.433 134 1794 exclusion phecode
191.11 Cancer of brain Neoplasms 0.901 0.745 – 1.09 0.279 110 1489 exclusion phecode
193 Thyroid cancer Neoplasms 1.01 0.88 – 1.16 0.863 229 2540 exclusion phecode
194 Cancer of other endocrine glands Neoplasms 0.927 0.783 – 1.1 0.377 152 1645 exclusion phecode
195 Cancer, suspected or other Neoplasms 1 0.964 – 1.05 0.857 4660 7374 exclusion phecode
195.1 Malignant neoplasm, other Neoplasms 1.01 0.967 – 1.05 0.729 4613 7364 exclusion phecode
195.3 Malignant neoplasm of head, face, and neck Neoplasms 0.958 0.834 – 1.1 0.548 222 2737 exclusion phecode
196 Radiotherapy Neoplasms 0.947 0.875 – 1.02 0.175 785 4687 exclusion phecode
197 Chemotherapy Neoplasms 1.04 0.978 – 1.1 0.214 1402 6568 exclusion phecode
198 Secondary malignant neoplasm Neoplasms 1.04 0.973 – 1.11 0.257 1187 6357 exclusion phecode
198.1 Secondary malignancy of lymph nodes Neoplasms 1.04 0.959 – 1.13 0.335 676 5782 exclusion phecode
198.2 Secondary malignancy of respiratory organs Neoplasms 0.915 0.802 – 1.04 0.19 250 2802 exclusion phecode
198.3
Secondary malignant neoplasm of digestive
Secondary malignant neoplasm of digestive systems
 Neoplasms 0.944 0.815 – 1.09 0.448 195 2213 exclusion phecode
198.4 Secondary malignant neoplasm of liver Neoplasms 1.11 0.948 – 1.3 0.195 174 2060 exclusion phecode
198.5 Secondary malignancy of brain/spine Neoplasms 0.9 0.746 – 1.09 0.271 121 1665 exclusion phecode
198.6 Secondary malignancy of bone Neoplasms 1.07 0.927 – 1.22 0.37 222 2238 exclusion phecode
198.7 Secondary malignant neoplasm of skin Neoplasms 0.879 0.693 – 1.12 0.288 67 946 exclusion phecode
199 Neoplasm of uncertain behavior Neoplasms 1.01 0.957 – 1.06 0.738 1970 7228 exclusion phecode
199.4 Neurofibromatosis Neoplasms 1.25 0.763 – 2.04 0.379 18 214 exclusion phecode
200 Myeloproliferative disease Neoplasms 0.983 0.896 – 1.08 0.712 548 3326 exclusion phecode
200.1 Polycythemia vera Neoplasms 1.04 0.866 – 1.24 0.686 143 736 exclusion phecode
201 Hodgkin's disease Neoplasms 0.862 0.668 – 1.11 0.254 73 464 exclusion phecode
202 Cancer of other lymphoid, histiocytic tissue Neoplasms 0.968 0.881 – 1.06 0.493 521 4481 exclusion phecode
202.2 Non-Hodgkins lymphoma Neoplasms 0.962 0.87 – 1.06 0.456 443 3850 exclusion phecode
202.21 Nodular lymphoma Neoplasms 0.874 0.76 – 1.01 0.0592 227 1964 exclusion phecode
202.22 Reticulosarcoma Neoplasms 1.28 0.984 – 1.65 0.0661 68 511 exclusion phecode
202.24 Large cell lymphoma Neoplasms 1.25 0.953 – 1.65 0.106 60 467 exclusion phecode
204 Leukemia Neoplasms 1.02 0.905 – 1.16 0.721 304 2114 exclusion phecode
204.1 Lymphoid leukemia Neoplasms 0.924 0.737 – 1.16 0.491 83 710 exclusion phecode
204.11 Lymphoid leukemia, acute Neoplasms 0.95 0.65 – 1.39 0.79 37 208 exclusion phecode
204.12 Lymphoid leukemia, chronic Neoplasms 0.932 0.719 – 1.21 0.597 58 537 exclusion phecode
204.2 Myeloid leukemia Neoplasms 1.05 0.879 – 1.26 0.575 147 879 exclusion phecode
204.21 Myeloid leukemia, acute Neoplasms 1 0.789 – 1.28 0.979 87 527 exclusion phecode
204.22 Myeloid leukemia, chronic Neoplasms 1.17 0.766 – 1.78 0.47 27 180 exclusion phecode
204.4 Multiple myeloma Neoplasms 0.989 0.799 – 1.23 0.921 97 648 exclusion phecode
208 Benign neoplasm of colon Neoplasms 0.993 0.956 – 1.03 0.701 5331 7680 exclusion phecode
209 Neuroendocrine tumors Neoplasms 0.944 0.751 – 1.19 0.625 79 759 exclusion phecode
210 Benign neoplasm of lip, oral cavity, and pharynx Neoplasms 0.972 0.879 – 1.08 0.584 431 5116 exclusion phecode
211
Benign neoplasm of other parts of digestive
Benign neoplasm of other parts of digestive system
 Neoplasms 0.996 0.956 – 1.04 0.829 3465 9146 exclusion phecode
212
Benign neoplasm of respiratory and
Benign neoplasm of respiratory and intrathoracic organs
 Neoplasms 1.02 0.927 – 1.11 0.732 516 4954 exclusion phecode
213 Benign neoplasm of bone and articular cartilage Neoplasms 0.982 0.887 – 1.09 0.728 454 2988 exclusion phecode
214 Lipoma Neoplasms 1.03 0.948 – 1.12 0.475 684 4089 exclusion phecode
214.1 Lipoma of skin and subcutaneous tissue Neoplasms 0.987 0.888 – 1.1 0.812 425 2510 exclusion phecode
215
Other benign neoplasm of connective and other
Other benign neoplasm of connective and other soft tissue
 Neoplasms 0.978 0.925 – 1.03 0.421 1536 10607 exclusion phecode
216 Benign neoplasm of skin Neoplasms 0.994 0.959 – 1.03 0.728 5302 8024 exclusion phecode
216.1 Screening for malignant neoplasms of the skin Neoplasms 0.765 0.609 – 0.961 0.0213 97 412 exclusion phecode
217 Vascular hamartomas and non-neoplastic nevi Neoplasms 1.01 0.94 – 1.08 0.804 989 4208 exclusion phecode
217.1 Nevus, non-neoplastic Neoplasms 1.02 0.944 – 1.09 0.68 957 4020 exclusion phecode
218 Benign neoplasm of uterus Neoplasms 0.981 0.925 – 1.04 0.52 1834 3634 exclusion phecode
218.1 Uterine leiomyoma Neoplasms 0.902 0.832 – 0.978 0.0129 774 3384 exclusion phecode
218.2 Other benign neoplasm of uterus Neoplasms 0.982 0.921 – 1.05 0.565 1490 3549 exclusion phecode
220 Benign neoplasm of ovary Neoplasms 0.961 0.846 – 1.09 0.539 307 1675 exclusion phecode
221 Benign neoplasm of other female genital organs Neoplasms 0.989 0.906 – 1.08 0.809 638 2931 exclusion phecode
222 Benign neoplasm of male genital organs Neoplasms 0.996 0.902 – 1.1 0.942 471 3425 exclusion phecode
223
Benign neoplasm of kidney and other urinary
Benign neoplasm of kidney and other urinary organs
 Neoplasms 1.08 0.974 – 1.19 0.147 493 2464 exclusion phecode
224 Benign neoplasm of eye Neoplasms 0.944 0.845 – 1.05 0.307 388 2260 exclusion phecode
224.1 Benign neoplasm of eye, uveal Neoplasms 0.963 0.857 – 1.08 0.526 355 1982 exclusion phecode
225
Benign neoplasm of brain and other parts of
Benign neoplasm of brain and other parts of nervous system
 Neoplasms 0.96 0.851 – 1.08 0.507 304 3205 exclusion phecode
225.1
Benign neoplasm of brain, cranial nerves
Benign neoplasm of brain, cranial nerves, meninges
 Neoplasms 1.02 0.88 – 1.17 0.825 215 2457 exclusion phecode
225.2 Benign neoplasm of spinal cord, meninges Neoplasms 0.93 0.741 – 1.17 0.533 91 773 exclusion phecode
226 Benign neoplasm of thyroid glands Neoplasms 0.989 0.894 – 1.09 0.823 450 3691 exclusion phecode
227
Benign neoplasm of other endocrine glands and
Benign neoplasm of other endocrine glands and related structures
 Neoplasms 1 0.907 – 1.1 0.988 452 4570 exclusion phecode
227.1 Benign neoplasm of adrenal gland Neoplasms 1.1 0.934 – 1.3 0.253 172 1372 exclusion phecode
227.2 Benign neoplasm of parathyroid gland Neoplasms 0.994 0.853 – 1.16 0.94 188 1991 exclusion phecode
227.3
Benign neoplasm of pituitary gland and
Benign neoplasm of pituitary gland and craniopharyngeal duct (pouch)
 Neoplasms 1.03 0.834 – 1.27 0.795 97 1212 exclusion phecode
228 Hemangioma and lymphangioma, any site Neoplasms 1.02 0.955 – 1.09 0.563 1112 6187 exclusion phecode
228.1 Hemangioma of skin and subcutaneous tissue Neoplasms 0.988 0.912 – 1.07 0.762 763 4017 exclusion phecode
229 Benign neoplasm of unspecified sites Neoplasms 0.997 0.946 – 1.05 0.915 1741 10461 exclusion phecode
229.1 Benign neoplasm of lymph nodes Neoplasms 1.02 0.952 – 1.09 0.597 1003 9537 exclusion phecode
240 Simple and unspecified goiter Endocrine/metabolic 0.978 0.886 – 1.08 0.663 479 2768 exclusion phecode
241 Nontoxic nodular goiter Endocrine/metabolic 0.974 0.914 – 1.04 0.425 1170 6073 exclusion phecode
241.1 Nontoxic uninodular goiter Endocrine/metabolic 0.974 0.907 – 1.05 0.465 933 5353 exclusion phecode
241.2 Nontoxic multinodular goiter Endocrine/metabolic 0.977 0.891 – 1.07 0.617 549 3335 exclusion phecode
242 Thyrotoxicosis with or without goiter Endocrine/metabolic 0.988 0.907 – 1.08 0.78 660 3751 exclusion phecode
242.1 Graves' disease Endocrine/metabolic 0.949 0.819 – 1.1 0.488 212 1409 exclusion phecode
242.2 Toxic multinodular goiter Endocrine/metabolic 1.26 0.92 – 1.73 0.15 48 345 exclusion phecode
242.3 Exophthalmos Endocrine/metabolic 1.09 0.877 – 1.34 0.448 103 795 exclusion phecode
242.31 Thyrotoxic exophthalmos Endocrine/metabolic 0.771 0.558 – 1.07 0.116 49 375 exclusion phecode
244 Hypothyroidism Endocrine/metabolic 1 0.96 – 1.05 0.87 2820 8953 exclusion phecode
244.1 Secondary hypothyroidism Endocrine/metabolic 0.999 0.915 – 1.09 0.988 580 4581 exclusion phecode
244.2 Acquired hypothyroidism Endocrine/metabolic 1.06 0.972 – 1.16 0.184 601 3449 exclusion phecode
244.4 Hypothyroidism NOS Endocrine/metabolic 1 0.955 – 1.05 0.995 2710 8831 exclusion phecode
245 Thyroiditis Endocrine/metabolic 0.984 0.88 – 1.1 0.772 377 2330 exclusion phecode
245.2 Chronic thyroiditis Endocrine/metabolic 0.947 0.837 – 1.07 0.38 311 1933 exclusion phecode
245.21 Chronic lymphocytic thyroiditis Endocrine/metabolic 0.932 0.825 – 1.05 0.263 309 1930 exclusion phecode
246 Other disorders of thyroid Endocrine/metabolic 0.978 0.929 – 1.03 0.39 2054 8241 exclusion phecode
246.2 Thyroid cyst Endocrine/metabolic 0.862 0.616 – 1.2 0.384 44 261 exclusion phecode
246.7 Abnormal results of function study of thyroid Endocrine/metabolic 1.03 0.93 – 1.13 0.608 490 2625 exclusion phecode
249 Secondary diabetes mellitus Endocrine/metabolic 0.958 0.871 – 1.05 0.379 827 1634 exclusion phecode
250 Diabetes mellitus Endocrine/metabolic 1.02 0.98 – 1.06 0.339 6856 6405 exclusion phecode
250.1 Type 1 diabetes Endocrine/metabolic 1 0.924 – 1.08 0.996 1882 2297 exclusion phecode
250.11 Type 1 diabetes with ketoacidosis Endocrine/metabolic 0.938 0.757 – 1.16 0.557 223 227 exclusion phecode
250.12 Type 1 diabetes with renal manifestations Endocrine/metabolic 0.928 0.802 – 1.07 0.317 460 563 exclusion phecode
250.13 Type 1 diabetes with ophthalmic manifestations Endocrine/metabolic 1.01 0.879 – 1.16 0.902 667 618 exclusion phecode
250.14 Type 1 diabetes with neurological manifestations Endocrine/metabolic 1.02 0.887 – 1.18 0.767 549 566 exclusion phecode
250.15
Diabetes type 1 with peripheral circulatory
Diabetes type 1 with peripheral circulatory disorders
 Endocrine/metabolic 0.964 0.752 – 1.24 0.772 143 198 exclusion phecode
250.2 Type 2 diabetes Endocrine/metabolic 1.04 0.996 – 1.09 0.0778 4737 5992 exclusion phecode
250.21 Type 2 diabetes with ketoacidosis Endocrine/metabolic 0.962 0.788 – 1.18 0.708 234 299 exclusion phecode
250.22 Type 2 diabetes with renal manifestations Endocrine/metabolic 1.04 0.97 – 1.12 0.25 1448 2651 exclusion phecode
250.23 Type 2 diabetes with ophthalmic manifestations Endocrine/metabolic 0.971 0.891 – 1.06 0.493 1321 1954 exclusion phecode
250.24 Type 2 diabetes with neurological manifestations Endocrine/metabolic 1.05 0.977 – 1.12 0.197 1854 3264 exclusion phecode
250.25
Diabetes type 2 with peripheral circulatory
Diabetes type 2 with peripheral circulatory disorders
 Endocrine/metabolic 1.08 0.969 – 1.19 0.172 699 1278 exclusion phecode
250.3 Insulin pump user Endocrine/metabolic 1.04 0.978 – 1.11 0.199 2378 4049 exclusion phecode
250.4 Abnormal glucose Endocrine/metabolic 1.02 0.973 – 1.06 0.484 5221 6224 exclusion phecode
250.41 Impaired fasting glucose Endocrine/metabolic 1.01 0.94 – 1.08 0.816 1229 3246 exclusion phecode
250.42 Other abnormal glucose Endocrine/metabolic 1.01 0.968 – 1.06 0.605 4736 6119 exclusion phecode
250.5 Glycosuria or Acetonuria Endocrine/metabolic 1.33 0.997 – 1.78 0.0526 85 251 exclusion phecode
250.6 Polyneuropathy in diabetes Endocrine/metabolic 1.02 0.943 – 1.1 0.671 1609 2677 exclusion phecode
250.7 Diabetic retinopathy Endocrine/metabolic 0.979 0.914 – 1.05 0.541 1350 2896 exclusion phecode
251 Other disorders of pancreatic internal secretion Endocrine/metabolic 1.04 0.953 – 1.13 0.38 637 2636 exclusion phecode
251.1 Hypoglycemia Endocrine/metabolic 1.05 0.953 – 1.16 0.321 810 1614 exclusion phecode
252 Disorders of parathyroid gland Endocrine/metabolic 1.01 0.942 – 1.08 0.773 956 5633 exclusion phecode
252.1 Hyperparathyroidism Endocrine/metabolic 1.02 0.946 – 1.09 0.652 890 5212 exclusion phecode
252.2 Hypoparathyroidism Endocrine/metabolic 1.1 0.934 – 1.29 0.257 169 1237 exclusion phecode
253
Disorders of the pituitary gland and its
Disorders of the pituitary gland and its hypothalamic control
 Endocrine/metabolic 1.05 0.937 – 1.18 0.395 337 2449 exclusion phecode
253.1 Pituitary hyperfunction Endocrine/metabolic 0.952 0.776 – 1.17 0.639 96 753 exclusion phecode
253.11 Acromegaly and gigantism Endocrine/metabolic 1.19 0.732 – 1.93 0.484 15 206 exclusion phecode
253.2 Pituitary hypofunction Endocrine/metabolic 1.23 0.965 – 1.57 0.0949 70 621 exclusion phecode
253.3 Diabetes insipidus Endocrine/metabolic 0.939 0.663 – 1.33 0.725 39 265 exclusion phecode
253.4 Anterior pituitary disorders Endocrine/metabolic 0.933 0.709 – 1.23 0.622 73 424 exclusion phecode
253.7 Other disorders of neurohypophysis Endocrine/metabolic 1.08 0.815 – 1.42 0.601 49 271 exclusion phecode
255 Disorders of adrenal glands Endocrine/metabolic 1.04 0.954 – 1.14 0.368 593 4088 exclusion phecode
255.1 Adrenal hyperfunction Endocrine/metabolic 1.02 0.867 – 1.2 0.809 159 1022 exclusion phecode
255.11 Cushing's syndrome Endocrine/metabolic 1.09 0.85 – 1.4 0.493 65 500 exclusion phecode
255.12 Hyperaldosteronism Endocrine/metabolic 1.03 0.782 – 1.37 0.819 62 377 exclusion phecode
255.2 Adrenal hypofunction Endocrine/metabolic 1.14 0.998 – 1.31 0.0531 253 1727 exclusion phecode
255.21 Glucocorticoid deficiency Endocrine/metabolic 1.15 1 – 1.33 0.0496 236 1627 exclusion phecode
256 Ovarian dysfunction Endocrine/metabolic 0.959 0.873 – 1.05 0.382 566 2620 exclusion phecode
256.4 Polycystic ovaries Endocrine/metabolic 0.975 0.871 – 1.09 0.663 393 1816 exclusion phecode
257 Testicular dysfunction Endocrine/metabolic 1 0.919 – 1.1 0.938 653 2754 exclusion phecode
257.1 Testicular hypofunction Endocrine/metabolic 1.02 0.937 – 1.12 0.599 633 2654 exclusion phecode
258 Iatrogenic endocrine disorders Endocrine/metabolic 1.09 0.788 – 1.51 0.601 45 297 exclusion phecode
258.1 Postablative ovarian failure Endocrine/metabolic 0.923 0.678 – 1.26 0.608 48 273 exclusion phecode
259 Other endocrine disorders Endocrine/metabolic 0.997 0.907 – 1.1 0.959 532 2945 exclusion phecode
260 Protein-calorie malnutrition Endocrine/metabolic 1.05 0.982 – 1.12 0.151 1084 5899 exclusion phecode
260.1 Cachexia Endocrine/metabolic 1.2 0.976 – 1.47 0.0837 111 602 exclusion phecode
260.2 severe protein-calorie malnutrition Endocrine/metabolic 1.07 0.981 – 1.17 0.126 609 3713 exclusion phecode
260.22 Nutritional marasmus Endocrine/metabolic 1.06 0.919 – 1.21 0.444 238 1351 exclusion phecode
260.3 Adult failure to thrive Endocrine/metabolic 1.05 0.92 – 1.2 0.464 260 1351 exclusion phecode
260.6 Anorexia Endocrine/metabolic 1.07 0.956 – 1.19 0.247 397 1977 exclusion phecode
260.7 Polyphagia Endocrine/metabolic 0.945 0.658 – 1.36 0.76 36 244 exclusion phecode
261 Vitamin deficiency Endocrine/metabolic 1 0.961 – 1.04 0.989 4227 7868 exclusion phecode
261.1 Vitamin A deficiency Endocrine/metabolic 0.991 0.714 – 1.38 0.957 43 191 exclusion phecode
261.2 Vitamin B-complex deficiencies Endocrine/metabolic 1.04 0.934 – 1.15 0.497 458 2033 exclusion phecode
261.4 Vitamin D deficiency Endocrine/metabolic 0.999 0.959 – 1.04 0.947 4013 7872 exclusion phecode
261.41 Rickets or osteomalacia Endocrine/metabolic 0.894 0.534 – 1.5 0.671 24 116 exclusion phecode
262 Mineral deficiency NEC Endocrine/metabolic 1.01 0.934 – 1.1 0.74 771 2818 exclusion phecode
263 Other nutritional deficiency Endocrine/metabolic 1.02 0.948 – 1.1 0.554 845 3745 exclusion phecode
264 Lack of normal physiological development Endocrine/metabolic 1.02 0.822 – 1.28 0.835 106 491 exclusion phecode
264.2 Failure to thrive (childhood) Endocrine/metabolic 1.11 0.821 – 1.51 0.49 48 253 exclusion phecode
264.9
Lack of normal physiological development
Lack of normal physiological development, unspecified
 Endocrine/metabolic 1.02 0.68 – 1.52 0.942 37 153 exclusion phecode
269 Proteinuria Endocrine/metabolic 1.06 0.996 – 1.13 0.0687 1269 4255 exclusion phecode
270
Disorders of protein plasma/amino-acid
Disorders of protein plasma/amino-acid transport and metabolism
 Endocrine/metabolic 0.969 0.879 – 1.07 0.522 502 2706 exclusion phecode
270.1 Disturbances of amino-acid transport Endocrine/metabolic 0.817 0.622 – 1.07 0.148 65 424 exclusion phecode
270.11
Disturbances of sulphur-bearing amino-acid
Disturbances of sulphur-bearing amino-acid metabolism
 Endocrine/metabolic 0.818 0.606 – 1.1 0.188 52 348 exclusion phecode
270.2 Disorders of amino-acid metabolism Endocrine/metabolic 0.779 0.585 – 1.04 0.0868 54 281 exclusion phecode
270.3 Disorders of plasma protein metabolism Endocrine/metabolic 1.02 0.912 – 1.13 0.764 404 2102 exclusion phecode
270.32 Paraproteinemia Endocrine/metabolic 0.962 0.832 – 1.11 0.595 224 1112 exclusion phecode
270.33 Amyloidosis Endocrine/metabolic 1.57 1.07 – 2.29 0.0201 29 195 exclusion phecode
270.34 Alpha-1-antitrypsin deficiency Endocrine/metabolic 0.999 0.694 – 1.44 0.996 31 214 exclusion phecode
270.38
Other specified disorders of plasma protein
Other specified disorders of plasma protein metabolism
 Endocrine/metabolic 1.07 0.899 – 1.28 0.436 160 822 exclusion phecode
271
Disorders of carbohydrate transport and
Disorders of carbohydrate transport and metabolism
 Endocrine/metabolic 0.914 0.865 – 0.965 0.00124 1630 7823 exclusion phecode
271.3
Intestinal disaccharidase deficiencies and
Intestinal disaccharidase deficiencies and disaccharide malabsorption
 Endocrine/metabolic 0.917 0.867 – 0.969 0.00221 1588 7615 exclusion phecode
271.9
Other disorders of carbohydrate transport and
Other disorders of carbohydrate transport and metabolism
 Endocrine/metabolic 0.748 0.563 – 0.993 0.0445 57 301 exclusion phecode
272 Disorders of lipoid metabolism Endocrine/metabolic 1.36 1.3 – 1.42 3e-44 7860 5445 exclusion phecode
272.1 Hyperlipidemia Endocrine/metabolic 1.36 1.3 – 1.42 8.39e-45 7841 5442 exclusion phecode
272.11 Hypercholesterolemia Endocrine/metabolic 1.57 1.48 – 1.67 2.4e-47 2816 4405 exclusion phecode
272.12 Hyperglyceridemia Endocrine/metabolic 1.26 1.16 – 1.37 9.92e-08 858 2329 exclusion phecode
272.13 Mixed hyperlipidemia Endocrine/metabolic 1.52 1.43 – 1.62 1.99e-37 2311 3622 exclusion phecode
272.9 Unspecified disorder of lipoid metabolism Endocrine/metabolic 1.33 1.11 – 1.59 0.00167 179 587 exclusion phecode
274 Gout and other crystal arthropathies Endocrine/metabolic 1.01 0.949 – 1.07 0.768 1270 6695 exclusion phecode
274.1 Gout Endocrine/metabolic 1.01 0.948 – 1.07 0.77 1211 6506 exclusion phecode
274.11 Gouty arthropathy Endocrine/metabolic 0.979 0.9 – 1.07 0.62 696 3370 exclusion phecode
274.2 Crystal arthropathies Endocrine/metabolic 1 0.808 – 1.24 0.98 107 536 exclusion phecode
274.21 Chondrocalcinosis Endocrine/metabolic 0.956 0.766 – 1.19 0.687 100 483 exclusion phecode
275 Disorders of mineral metabolism Endocrine/metabolic 1.02 0.969 – 1.07 0.492 2063 9951 exclusion phecode
275.1 Disorders of iron metabolism Hematopoietic 0.897 0.739 – 1.09 0.271 119 630 exclusion phecode
275.11 Hereditary hemochromatosis Hematopoietic 0.759 0.559 – 1.03 0.0769 42 295 exclusion phecode
275.2 Disorders of copper metabolism Endocrine/metabolic 0.965 0.679 – 1.37 0.844 40 193 exclusion phecode
275.3 Disorders of magnesium metabolism Endocrine/metabolic 1.07 0.978 – 1.17 0.14 581 3268 exclusion phecode
275.5 Disorders of calcium/phosphorus metabolism Endocrine/metabolic 1 0.95 – 1.06 0.881 1571 8440 exclusion phecode
275.51 Hypocalcemia Endocrine/metabolic 0.993 0.888 – 1.11 0.905 373 2325 exclusion phecode
275.53 Disorders of phosphorus metabolism Endocrine/metabolic 0.98 0.902 – 1.06 0.625 700 3698 exclusion phecode
275.6 Hypercalcemia Endocrine/metabolic 1.01 0.934 – 1.1 0.774 746 4061 exclusion phecode
276
Disorders of fluid, electrolyte, and acid-base
Disorders of fluid, electrolyte, and acid-base balance
 Endocrine/metabolic 1.02 0.981 – 1.06 0.334 4452 8793 exclusion phecode
276.1 Electrolyte imbalance Endocrine/metabolic 1.02 0.978 – 1.06 0.353 3242 8214 exclusion phecode
276.11 Hyperosmolality and/or hypernatremia Endocrine/metabolic 0.979 0.865 – 1.11 0.73 311 1443 exclusion phecode
276.12 Hyposmolality and/or hyponatremia Endocrine/metabolic 1.03 0.965 – 1.09 0.414 1266 5574 exclusion phecode
276.13 Hyperpotassemia Endocrine/metabolic 1.02 0.967 – 1.08 0.452 1739 6217 exclusion phecode
276.14 Hypopotassemia Endocrine/metabolic 1.03 0.962 – 1.1 0.415 1125 5009 exclusion phecode
276.4 Acid-base balance disorder Endocrine/metabolic 1.04 0.972 – 1.11 0.27 1203 4978 exclusion phecode
276.41 Acidosis Endocrine/metabolic 1.01 0.946 – 1.09 0.691 1047 4348 exclusion phecode
276.42 Alkalosis Endocrine/metabolic 1.14 1 – 1.3 0.0489 277 1221 exclusion phecode
276.5 Hypovolemia Endocrine/metabolic 1.04 0.99 – 1.09 0.119 2238 8137 exclusion phecode
276.6 Fluid overload Endocrine/metabolic 1 0.932 – 1.08 0.902 926 3306 exclusion phecode
276.8 Polydipsia Endocrine/metabolic 1.07 0.819 – 1.4 0.615 70 340 exclusion phecode
277 Other disorders of metabolism Endocrine/metabolic 1.03 0.984 – 1.08 0.196 2308 9179 exclusion phecode
277.2
Other disorders of purine and pyrimidine
Other disorders of purine and pyrimidine metabolism
 Endocrine/metabolic 0.929 0.81 – 1.07 0.29 266 1464 exclusion phecode
277.4 Disorders of bilirubin excretion Endocrine/metabolic 0.934 0.835 – 1.05 0.237 385 2029 exclusion phecode
277.5 Other disorders of lipoid metabolism Endocrine/metabolic 0.964 0.879 – 1.06 0.434 585 2859 exclusion phecode
277.51 Lipoprotein disorders Endocrine/metabolic 0.95 0.858 – 1.05 0.317 495 2401 exclusion phecode
277.7 Dysmetabolic syndrome X Endocrine/metabolic 1.07 0.981 – 1.17 0.129 662 2756 exclusion phecode
278 Overweight, obesity and other hyperalimentation Endocrine/metabolic 0.994 0.96 – 1.03 0.753 7389 6066 exclusion phecode
278.1 Obesity Endocrine/metabolic 0.986 0.951 – 1.02 0.458 6433 6061 exclusion phecode
278.11 Morbid obesity Endocrine/metabolic 1 0.958 – 1.05 0.969 3481 5982 exclusion phecode
278.3 Localized adiposity Endocrine/metabolic 0.971 0.819 – 1.15 0.73 166 760 exclusion phecode
278.4 Abnormal weight gain Endocrine/metabolic 1.01 0.941 – 1.08 0.859 1201 3801 exclusion phecode
279 Disorders involving the immune mechanism Endocrine/metabolic 0.974 0.921 – 1.03 0.363 1566 7112 exclusion phecode
279.1 Immunity deficiency Endocrine/metabolic 0.978 0.898 – 1.07 0.613 663 2916 exclusion phecode
279.11 Deficiency of humoral immunity Endocrine/metabolic 1.06 0.896 – 1.26 0.486 174 856 exclusion phecode
279.2 Autoimmune disease NEC Endocrine/metabolic 1 0.891 – 1.12 0.995 371 2000 exclusion phecode
279.7 Other immunological findings Endocrine/metabolic 1 0.96 – 1.05 0.907 2830 9010 exclusion phecode
279.8
Other specified disorders involving the immune
Other specified disorders involving the immune mechanism
 Endocrine/metabolic 0.923 0.813 – 1.05 0.209 310 1586 exclusion phecode
280 Iron deficiency anemias Hematopoietic 1.09 1.04 – 1.15 0.000161 2605 7054 exclusion phecode
280.1
Iron deficiency anemias, unspecified or not due
Iron deficiency anemias, unspecified or not due to blood loss
 Hematopoietic 1.09 1.04 – 1.15 0.000269 2531 6990 exclusion phecode
280.2
Iron deficiency anemia secondary to blood loss
Iron deficiency anemia secondary to blood loss (chronic)
 Hematopoietic 1.08 1.01 – 1.16 0.0336 992 3984 exclusion phecode
281 Other deficiency anemia Hematopoietic 1.14 1 – 1.29 0.0509 314 1184 exclusion phecode
281.1 Megaloblastic anemia Hematopoietic 1.09 0.908 – 1.32 0.346 149 604 exclusion phecode
281.11 Pernicious anemia Hematopoietic 1.02 0.773 – 1.36 0.87 67 275 exclusion phecode
281.12 Other vitamin B12 deficiency anemia Hematopoietic 1.11 0.882 – 1.4 0.375 105 435 exclusion phecode
281.9 Deficiency anemias Hematopoietic 1.09 0.918 – 1.29 0.326 183 651 exclusion phecode
282 Hereditary hemolytic anemias Hematopoietic 0.923 0.781 – 1.09 0.352 182 805 exclusion phecode
282.8 Other hemoglobinopathies Hematopoietic 0.896 0.733 – 1.1 0.284 128 591 exclusion phecode
282.9 Other hereditary hemolytic anemias Hematopoietic 1.01 0.821 – 1.25 0.912 111 486 exclusion phecode
283 Acquired hemolytic anemias Hematopoietic 0.871 0.683 – 1.11 0.268 95 388 exclusion phecode
283.1 Autoimmune hemolytic anemias Hematopoietic 0.752 0.522 – 1.08 0.126 37 160 exclusion phecode
284 Aplastic anemia Hematopoietic 1.08 0.957 – 1.21 0.222 366 1620 exclusion phecode
284.1 Pancytopenia Hematopoietic 1.1 0.969 – 1.25 0.142 315 1419 exclusion phecode
285 Other anemias Hematopoietic 1.07 1.03 – 1.11 0.000287 5175 7676 exclusion phecode
285.1 Acute posthemorrhagic anemia Hematopoietic 1.12 1.05 – 1.18 0.000281 1479 6091 exclusion phecode
285.2 Anemia of chronic disease Hematopoietic 1.06 0.995 – 1.14 0.0678 1154 4594 exclusion phecode
285.21 Anemia in chronic kidney disease Hematopoietic 1.02 0.934 – 1.11 0.661 697 2380 exclusion phecode
285.22 Anemia in neoplastic disease Hematopoietic 1.09 0.945 – 1.26 0.235 239 1436 exclusion phecode
286 Coagulation defects Hematopoietic 1.06 1 – 1.11 0.0397 1800 8293 exclusion phecode
286.1 Congenital coagulation defects Hematopoietic 0.893 0.708 – 1.13 0.341 90 658 exclusion phecode
286.11 Von willebrand's disease Hematopoietic 0.685 0.444 – 1.06 0.0881 25 206 exclusion phecode
286.12
Congenital deficiency of other clotting factors
Congenital deficiency of other clotting factors (including factor VII)
 Hematopoietic 0.963 0.709 – 1.31 0.809 47 353 exclusion phecode
286.2
Encounter for long-term (current) use of
Encounter for long-term (current) use of anticoagulants
 Hematopoietic 1.08 1.02 – 1.14 0.0063 1785 6466 exclusion phecode
286.3
Coagulation defects complicating pregnancy or
Coagulation defects complicating pregnancy or postpartum
 Hematopoietic 0.68 0.489 – 0.945 0.0216 43 276 exclusion phecode
286.4 Acquired coagulation factor deficiency Hematopoietic 1.01 0.831 – 1.22 0.932 137 695 exclusion phecode
286.5
Hemorrhagic disorder due to intrinsic
Hemorrhagic disorder due to intrinsic circulating anticoagulants
 Hematopoietic 1.3 0.999 – 1.69 0.0509 79 360 exclusion phecode
286.6 Defibrination syndrome Hematopoietic 1.04 0.977 – 1.11 0.21 1147 6409 exclusion phecode
286.7 Other and unspecified coagulation defects Hematopoietic 1.05 0.987 – 1.11 0.124 1395 7344 exclusion phecode
286.8 Hypercoagulable state Hematopoietic 1.04 0.922 – 1.17 0.546 343 2135 exclusion phecode
286.81 Primary hypercoagulable state Hematopoietic 1.03 0.914 – 1.16 0.628 329 2063 exclusion phecode
286.9 Abnormal coagulation profile Hematopoietic 1.04 0.956 – 1.14 0.347 681 2898 exclusion phecode
287 Purpura and other hemorrhagic conditions Hematopoietic 1.11 1.05 – 1.17 0.000358 1682 7190 exclusion phecode
287.1 Spontaneous ecchymoses Hematopoietic 1.18 0.961 – 1.46 0.113 117 553 exclusion phecode
287.3 Thrombocytopenia Hematopoietic 1.11 1.05 – 1.18 0.000271 1520 6676 exclusion phecode
287.31 Primary thrombocytopenia Hematopoietic 1.11 0.963 – 1.27 0.154 245 1483 exclusion phecode
287.32 Secondary thrombocytopenia Hematopoietic 1.05 0.915 – 1.19 0.511 267 1445 exclusion phecode
287.4 Qualitative platelet defects Hematopoietic 1.19 0.872 – 1.63 0.271 52 281 exclusion phecode
288 Diseases of white blood cells Hematopoietic 1.01 0.965 – 1.06 0.647 2345 9026 exclusion phecode
288.1 Decreased white blood cell count Hematopoietic 1.01 0.927 – 1.09 0.903 739 3957 exclusion phecode
288.11 Neutropenia Hematopoietic 0.973 0.878 – 1.08 0.596 483 2720 exclusion phecode
288.2 Elevated white blood cell count Hematopoietic 1 0.955 – 1.05 0.89 2041 8728 exclusion phecode
288.3 Eosinophilia Hematopoietic 1.06 0.837 – 1.33 0.647 75 520 exclusion phecode
289 Other diseases of blood and blood-forming organs Hematopoietic 1.03 0.962 – 1.11 0.366 930 4554 exclusion phecode
289.3
Personal history of diseases of blood and
Personal history of diseases of blood and blood-forming organs
 Hematopoietic 1.13 1.02 – 1.26 0.0215 484 2321 exclusion phecode
289.4 Lymphadenitis Hematopoietic 1.02 0.969 – 1.08 0.389 1551 8568 exclusion phecode
289.5 Diseases of spleen Hematopoietic 1.07 0.913 – 1.25 0.41 218 1040 exclusion phecode
289.8 Polycythemia, secondary Hematopoietic 0.994 0.838 – 1.18 0.946 163 766 exclusion phecode
289.9 Abnormality of red blood cells Hematopoietic 0.989 0.854 – 1.14 0.878 222 1099 exclusion phecode
290
Delirium dementia and amnestic and other
Delirium dementia and amnestic and other cognitive disorders
 Mental Disorders 1.12 1.03 – 1.21 0.0113 678 3018 exclusion phecode
290.1 Dementias Mental Disorders 1.14 0.998 – 1.3 0.0536 276 1269 exclusion phecode
290.11 Alzheimer's disease Mental Disorders 1.33 1.03 – 1.7 0.0265 82 362 exclusion phecode
290.12 Dementia with cerebral degenerations Mental Disorders 1.15 0.852 – 1.56 0.358 53 202 exclusion phecode
290.13 Senile dementia Mental Disorders 1.05 0.891 – 1.24 0.56 179 787 exclusion phecode
290.16 Vascular dementia Mental Disorders 1.16 0.851 – 1.59 0.343 55 198 exclusion phecode
290.2 Delirium due to conditions classified elsewhere Mental Disorders 1.1 0.985 – 1.23 0.0919 402 1947 exclusion phecode
290.3
Other persistent mental disorders due to
Other persistent mental disorders due to conditions classified elsewhere
 Mental Disorders 1.11 0.998 – 1.23 0.0558 474 2365 exclusion phecode
291
Other specified nonpsychotic and/or transient
Other specified nonpsychotic and/or transient mental disorders
 Mental Disorders 1.02 0.966 – 1.09 0.417 1378 6571 exclusion phecode
291.1
Transient mental disorders due to conditions
Transient mental disorders due to conditions classified elsewhere
 Mental Disorders 1.08 0.871 – 1.33 0.493 91 509 exclusion phecode
291.4
Specific nonpsychotic mental disorders due to
Specific nonpsychotic mental disorders due to brain damage
 Mental Disorders 1.03 0.9 – 1.19 0.629 247 1294 exclusion phecode
291.8 Alteration of consciousness Mental Disorders 1.03 0.962 – 1.1 0.421 1120 5326 exclusion phecode
292 Neurological disorders Mental Disorders 1.01 0.968 – 1.06 0.605 2690 9676 exclusion phecode
292.1 Aphasia/speech disturbance Mental Disorders 1 0.93 – 1.08 0.939 817 5038 exclusion phecode
292.11 Aphasia Mental Disorders 1 0.883 – 1.14 0.966 296 1634 exclusion phecode
292.12 Symbolic dysfunction Mental Disorders 0.865 0.689 – 1.09 0.213 84 513 exclusion phecode
292.2 Mild cognitive impairment Mental Disorders 1.06 0.918 – 1.23 0.414 239 1003 exclusion phecode
292.3 Memory loss Mental Disorders 1.04 0.974 – 1.12 0.224 1006 4687 exclusion phecode
292.4 Altered mental status Mental Disorders 1.01 0.945 – 1.07 0.871 1313 5957 exclusion phecode
292.5 Transient alteration of awareness Mental Disorders 0.961 0.834 – 1.11 0.585 237 1203 exclusion phecode
292.6 Hallucinations Mental Disorders 0.926 0.759 – 1.13 0.452 115 555 exclusion phecode
293 Symptoms involving head and neck Mental Disorders 0.972 0.837 – 1.13 0.711 203 1211 exclusion phecode
293.1
Swelling, mass, or lump in head and neck
Swelling, mass, or lump in head and neck [Space-occupying lesion, intracranial NOS]
 Mental Disorders 1 0.952 – 1.06 0.864 1578 10628 exclusion phecode
295 Schizophrenia and other psychotic disorders Mental Disorders 0.916 0.823 – 1.02 0.107 485 1593 exclusion phecode
295.1 Schizophrenia Mental Disorders 1.04 0.763 – 1.43 0.789 57 265 exclusion phecode
295.2 Paranoid disorders Mental Disorders 0.802 0.598 – 1.07 0.139 67 214 exclusion phecode
295.3 Psychosis Mental Disorders 0.931 0.829 – 1.05 0.228 411 1366 exclusion phecode
296 Mood disorders Mental Disorders 0.98 0.939 – 1.02 0.366 5690 3885 exclusion phecode
296.1 Bipolar Mental Disorders 1.04 0.937 – 1.14 0.493 540 2064 exclusion phecode
296.2 Depression Mental Disorders 0.987 0.945 – 1.03 0.56 5505 3883 exclusion phecode
296.22 Major depressive disorder Mental Disorders 0.983 0.941 – 1.03 0.463 5084 3881 exclusion phecode
297 Suicidal ideation or attempt Mental Disorders 0.986 0.886 – 1.1 0.789 486 1665 exclusion phecode
297.1 Suicidal ideation Mental Disorders 0.976 0.866 – 1.1 0.696 386 1369 exclusion phecode
297.2 Suicide or self-inflicted injury Mental Disorders 1 0.822 – 1.22 0.979 137 503 exclusion phecode
300 Anxiety disorders Mental Disorders 0.989 0.947 – 1.03 0.628 5712 3882 exclusion phecode
300.1 Anxiety disorder Mental Disorders 0.987 0.944 – 1.03 0.553 5333 3886 exclusion phecode
300.11 Generalized anxiety disorder Mental Disorders 0.975 0.923 – 1.03 0.358 2466 3809 exclusion phecode
300.12 Agorophobia, social phobia, and panic disorder Mental Disorders 0.961 0.877 – 1.05 0.396 660 2111 exclusion phecode
300.13 Phobia Mental Disorders 0.879 0.791 – 0.976 0.016 496 1832 exclusion phecode
300.3 Obsessive-compulsive disorders Mental Disorders 0.858 0.716 – 1.03 0.0958 160 644 exclusion phecode
300.4 Dysthymic disorder Mental Disorders 0.969 0.904 – 1.04 0.384 1214 3090 exclusion phecode
300.8 Acute reaction to stress Mental Disorders 0.951 0.828 – 1.09 0.478 279 1013 exclusion phecode
300.9 Posttraumatic stress disorder Mental Disorders 0.974 0.854 – 1.11 0.699 309 1427 exclusion phecode
301 Personality disorders Mental Disorders 0.932 0.794 – 1.09 0.388 220 858 exclusion phecode
301.2 Antisocial/borderline personality disorder Mental Disorders 0.891 0.713 – 1.11 0.307 113 459 exclusion phecode
302 Sexual and gender identity disorders Mental Disorders 0.965 0.906 – 1.03 0.258 1823 2814 exclusion phecode
302.1 Decreased libido Mental Disorders 0.847 0.734 – 0.977 0.023 260 1019 exclusion phecode
303 Psychogenic and somatoform disorders Mental Disorders 0.975 0.929 – 1.02 0.305 3550 3764 exclusion phecode
303.1 Dissociative disorder Mental Disorders 0.94 0.722 – 1.22 0.648 68 340 exclusion phecode
303.3 Psychogenic disorder Mental Disorders 0.969 0.923 – 1.02 0.214 3426 3727 exclusion phecode
303.31
Gastrointestinal malfunction arising from
Gastrointestinal malfunction arising from mental factors
 Mental Disorders 0.871 0.746 – 1.02 0.0772 228 939 exclusion phecode
303.4 Somatoform disorder Mental Disorders 0.962 0.866 – 1.07 0.475 465 1998 exclusion phecode
304 Adjustment reaction Mental Disorders 0.941 0.887 – 0.998 0.0431 1908 3837 exclusion phecode
305.2 Eating disorder Mental Disorders 0.923 0.833 – 1.02 0.126 521 1630 exclusion phecode
306 Other mental disorder Mental Disorders 1.02 0.946 – 1.11 0.57 935 2657 exclusion phecode
306.1 Mental disorders durring/after pregnancy Mental Disorders 1.23 1.06 – 1.43 0.00755 281 667 exclusion phecode
306.9 Tension headache Mental Disorders 0.99 0.88 – 1.11 0.869 391 1452 exclusion phecode
312 Conduct disorders Mental Disorders 0.892 0.728 – 1.09 0.27 126 653 exclusion phecode
312.3 Impulse control disorder Mental Disorders 0.816 0.553 – 1.2 0.305 35 229 exclusion phecode
313 Pervasive developmental disorders Mental Disorders 0.928 0.85 – 1.01 0.0997 600 3926 exclusion phecode
313.1 Attention deficit hyperactivity disorder Mental Disorders 0.917 0.833 – 1.01 0.0769 512 3473 exclusion phecode
313.2 Tics and stuttering Mental Disorders 0.866 0.622 – 1.21 0.395 38 170 exclusion phecode
313.3 Autism Mental Disorders 0.889 0.586 – 1.35 0.579 33 143 exclusion phecode
315 Develomental delays and disorders Mental Disorders 1.06 0.948 – 1.2 0.293 343 1828 exclusion phecode
315.1 Learning disorder Mental Disorders 0.799 0.568 – 1.12 0.197 44 231 exclusion phecode
315.2 Speech and language disorder Mental Disorders 0.955 0.775 – 1.18 0.665 106 636 exclusion phecode
316 Substance addiction and disorders Mental Disorders 1.05 0.994 – 1.12 0.0797 1415 8152 exclusion phecode
316.1 Polyneuropathy due to drugs Mental Disorders 1.02 0.876 – 1.19 0.795 208 1492 exclusion phecode
317 Alcohol-related disorders Mental Disorders 1.01 0.947 – 1.08 0.71 1035 5942 exclusion phecode
317.1 Alcoholism Mental Disorders 1 0.93 – 1.08 0.973 846 5075 exclusion phecode
317.11 Alcoholic liver damage Mental Disorders 1 0.865 – 1.16 0.962 214 1112 exclusion phecode
318 Tobacco use disorder Mental Disorders 1.02 0.976 – 1.06 0.41 3208 9024 exclusion phecode
320 Meningitis Neurological 1.2 0.999 – 1.43 0.0507 147 1019 exclusion phecode
323 Encephalitis Neurological 0.994 0.791 – 1.25 0.955 85 507 exclusion phecode
323.8 Encephalitis, non-infectious Neurological 0.927 0.727 – 1.18 0.544 75 418 exclusion phecode
324 Other CNS infection and poliomyelitis Neurological 1.05 0.846 – 1.31 0.649 90 791 exclusion phecode
325
Phlebitis and thrombophlebitis of intracranial
Phlebitis and thrombophlebitis of intracranial venous sinuses
 Neurological 0.814 0.527 – 1.26 0.353 22 157 exclusion phecode
327 Sleep disorders Neurological 0.988 0.954 – 1.02 0.515 6587 6802 exclusion phecode
327.1 Hypersomnia Neurological 1.04 0.977 – 1.11 0.217 1241 4463 exclusion phecode
327.3 Sleep apnea Neurological 0.999 0.961 – 1.04 0.975 4833 6737 exclusion phecode
327.31 Central/nonobstroctive sleep apnea Neurological 0.997 0.877 – 1.13 0.963 301 1238 exclusion phecode
327.32 Obstructive sleep apnea Neurological 0.992 0.953 – 1.03 0.713 4324 6613 exclusion phecode
327.4 Insomnia Neurological 0.977 0.934 – 1.02 0.303 2919 6671 exclusion phecode
327.41 Organic or persistent insomnia Neurological 0.915 0.841 – 0.995 0.0377 743 2829 exclusion phecode
327.5 Parasomnia Neurological 1.01 0.898 – 1.15 0.816 362 1416 exclusion phecode
327.6 Circadian rhythm sleep disorder Neurological 0.934 0.782 – 1.12 0.457 172 747 exclusion phecode
327.7 Sleep related movement disorders Neurological 0.909 0.844 – 0.979 0.0118 897 3811 exclusion phecode
327.71 Restless legs syndrome Neurological 0.904 0.834 – 0.979 0.0132 760 3376 exclusion phecode
327.72 Sleep related leg cramps Neurological 1.03 0.759 – 1.38 0.871 57 187 exclusion phecode
331 Other cerebral degenerations Neurological 1.09 0.961 – 1.24 0.179 317 1841 exclusion phecode
331.1 Hydrocephalus Neurological 1.25 0.984 – 1.6 0.0678 72 631 exclusion phecode
331.9 Cerebral degeneration, unspecified Neurological 0.971 0.838 – 1.13 0.695 241 1117 exclusion phecode
332 Parkinson's disease Neurological 0.891 0.757 – 1.05 0.167 173 1124 exclusion phecode
333
Extrapyramidal disease and abnormal movement
Extrapyramidal disease and abnormal movement disorders
 Neurological 0.946 0.892 – 1 0.0679 1356 7035 exclusion phecode
333.1 Essential tremor Neurological 0.97 0.868 – 1.09 0.598 367 1998 exclusion phecode
333.2 Myoclonus Neurological 1.01 0.804 – 1.26 0.953 81 425 exclusion phecode
333.4 Torsion dystonia Neurological 1.02 0.841 – 1.23 0.861 133 857 exclusion phecode
333.8 Other degenerative diseases of the basal ganglia Neurological 1.14 0.846 – 1.54 0.386 56 273 exclusion phecode
334 Degenerative disease of the spinal cord Neurological 0.893 0.801 – 0.995 0.0397 381 2602 exclusion phecode
334.1 Spinocerebellar disease Neurological 0.769 0.54 – 1.1 0.146 42 209 exclusion phecode
334.2 Anterior horn cell disease Neurological 0.887 0.637 – 1.23 0.476 36 309 exclusion phecode
334.21 Amyotrophic Lateral Sclerosis Neurological 0.986 0.659 – 1.48 0.946 25 196 exclusion phecode
335 Multiple sclerosis Neurological 0.883 0.741 – 1.05 0.166 145 975 exclusion phecode
337 Disorders of the autonomic nervous system Neurological 0.977 0.884 – 1.08 0.644 456 2449 exclusion phecode
337.1 Peripheral autonomic neuropathy Neurological 0.932 0.82 – 1.06 0.283 295 1431 exclusion phecode
338 Pain Neurological 0.995 0.961 – 1.03 0.798 7205 6250 exclusion phecode
338.1 Acute pain Neurological 0.992 0.954 – 1.03 0.679 5140 6206 exclusion phecode
338.2 Chronic pain Neurological 0.997 0.959 – 1.04 0.901 4759 6218 exclusion phecode
339 Other headache syndromes Neurological 0.988 0.949 – 1.03 0.564 3891 8649 exclusion phecode
340 Migraine Neurological 0.98 0.935 – 1.03 0.389 2692 7492 exclusion phecode
340.1 Migrain with aura Neurological 1.01 0.951 – 1.07 0.783 1545 5634 exclusion phecode
341
Other demyelinating diseases of central nervous
Other demyelinating diseases of central nervous system
 Neurological 0.892 0.665 – 1.2 0.446 63 363 exclusion phecode
342 Hemiplegia Neurological 0.949 0.824 – 1.09 0.467 240 1217 exclusion phecode
343 Infantile cerebral palsy Neurological 1.03 0.675 – 1.56 0.9 25 186 exclusion phecode
344 Other paralytic syndromes Neurological 1.02 0.894 – 1.16 0.797 287 1641 exclusion phecode
345 Epilepsy, recurrent seizures, convulsions Neurological 0.978 0.911 – 1.05 0.539 910 6495 exclusion phecode
345.1 Epilepsy Neurological 0.926 0.816 – 1.05 0.23 277 1899 exclusion phecode
345.11 Generalized convulsive epilepsy Neurological 0.914 0.727 – 1.15 0.437 81 573 exclusion phecode
345.12 Partial epilepsy Neurological 0.92 0.791 – 1.07 0.278 199 1343 exclusion phecode
345.3 Convulsions Neurological 0.968 0.9 – 1.04 0.384 858 6114 exclusion phecode
346
Abnormal findings on study of brain and/or
Abnormal findings on study of brain and/or nervous system
 Neurological 0.821 0.648 – 1.04 0.102 81 464 exclusion phecode
346.1
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of skull and head
 Neurological 1.01 0.931 – 1.1 0.777 671 3803 exclusion phecode
346.2
Nonspecific abnormal results of function study
Nonspecific abnormal results of function study of brain and central nervous system
 Neurological 0.845 0.627 – 1.14 0.267 56 309 exclusion phecode
346.3
Nonspecific abnormal findings in cerebrospinal
Nonspecific abnormal findings in cerebrospinal fluid
 Neurological 0.883 0.613 – 1.27 0.506 40 254 exclusion phecode
347 Cataplexy and narcolepsy Neurological 1.19 0.813 – 1.73 0.375 36 303 exclusion phecode
348 Other conditions of brain Neurological 0.969 0.893 – 1.05 0.451 691 4573 exclusion phecode
348.2 Cerebral edema and compression of brain Neurological 0.922 0.805 – 1.05 0.234 236 2177 exclusion phecode
348.4 Cerebral cysts Neurological 0.889 0.691 – 1.14 0.363 78 596 exclusion phecode
348.7 Coma Neurological 1.12 0.895 – 1.39 0.329 100 607 exclusion phecode
348.8 Encephalopathy, not elsewhere classified Neurological 1.04 0.935 – 1.15 0.48 428 2220 exclusion phecode
348.9 Other conditions of brain, NOS Neurological 0.992 0.921 – 1.07 0.838 818 5822 exclusion phecode
349
Other and unspecified disorders of the nervous
Other and unspecified disorders of the nervous system
 Neurological 0.96 0.86 – 1.07 0.475 374 2287 exclusion phecode
350 Abnormal movement Neurological 0.998 0.956 – 1.04 0.908 3170 9770 exclusion phecode
350.1 Abnormal involuntary movements Neurological 1 0.95 – 1.06 0.894 1626 7807 exclusion phecode
350.2 Abnormality of gait Neurological 0.982 0.932 – 1.03 0.479 1930 7687 exclusion phecode
350.3 Lack of coordination Neurological 0.988 0.896 – 1.09 0.81 507 2672 exclusion phecode
350.5 Abnormal reflex Neurological 0.862 0.687 – 1.08 0.2 90 531 exclusion phecode
350.6 Disturbances of sensation of smell and taste Neurological 0.966 0.834 – 1.12 0.641 211 1452 exclusion phecode
351 Other peripheral nerve disorders Neurological 0.992 0.953 – 1.03 0.714 3549 8347 exclusion phecode
352 Disorders of other cranial nerves Neurological 0.966 0.879 – 1.06 0.468 511 4005 exclusion phecode
352.1 Trigeminal nerve disorders [CN5] Neurological 0.898 0.769 – 1.05 0.175 196 1200 exclusion phecode
352.2 Facial nerve disorders [CN7] Neurological 0.985 0.863 – 1.12 0.823 263 1838 exclusion phecode
353 Nerve root and plexus disorders Neurological 0.983 0.934 – 1.04 0.522 1921 8010 exclusion phecode
353.1 Nerve plexus lesions Neurological 1.07 0.881 – 1.31 0.478 126 948 exclusion phecode
353.2 Nerve root lesions Neurological 0.881 0.657 – 1.18 0.396 56 328 exclusion phecode
355 Complex regional/central pain syndrome Neurological 0.852 0.73 – 0.993 0.041 192 1224 exclusion phecode
355.1 Chronic pain syndrome Neurological 1.02 0.909 – 1.14 0.773 396 2050 exclusion phecode
356 Hereditary and idiopathic peripheral neuropathy Neurological 0.986 0.927 – 1.05 0.658 1319 5774 exclusion phecode
357 Inflammatory and toxic neuropathy Neurological 1.03 0.98 – 1.09 0.226 1770 8017 exclusion phecode
358 Myoneural disorders Neurological 0.982 0.894 – 1.08 0.706 531 3149 exclusion phecode
358.1 Myasthenia gravis Neurological 0.881 0.57 – 1.36 0.57 30 267 exclusion phecode
359 Muscular dystrophies and other myopathies Neurological 0.93 0.846 – 1.02 0.131 519 3049 exclusion phecode
359.1 Muscular dystrophies Neurological 0.739 0.442 – 1.24 0.25 21 166 exclusion phecode
359.2 Myopathy Neurological 0.932 0.847 – 1.02 0.146 505 2933 exclusion phecode
360 Disorders of the globe Sense Organs 1.01 0.793 – 1.28 0.948 83 405 exclusion phecode
360.2 Progressive myopia Sense Organs 1.09 0.781 – 1.51 0.624 48 194 exclusion phecode
361 Retinal detachments and defects Sense Organs 0.866 0.777 – 0.964 0.00881 412 2085 exclusion phecode
361.1 Retinal detachment with retinal defect Sense Organs 0.946 0.807 – 1.11 0.5 177 884 exclusion phecode
362 Other retinal disorders Sense Organs 0.976 0.927 – 1.03 0.365 2140 5763 exclusion phecode
362.2
Degeneration of macula and posterior pole of
Degeneration of macula and posterior pole of retina
 Sense Organs 0.982 0.919 – 1.05 0.593 1259 3982 exclusion phecode
362.21 Macular degeneration, dry Sense Organs 0.92 0.794 – 1.07 0.265 245 865 exclusion phecode
362.22 Macular degeneration, wet Sense Organs 0.861 0.678 – 1.09 0.222 82 348 exclusion phecode
362.23 Cystoid macular degeneration of retina Sense Organs 1.02 0.887 – 1.18 0.743 247 1039 exclusion phecode
362.26 Macular puckering of retina Sense Organs 1.01 0.919 – 1.1 0.911 619 2448 exclusion phecode
362.27 Drusen (degenerative) of retina Sense Organs 0.954 0.838 – 1.08 0.471 288 1260 exclusion phecode
362.29 Macular degeneration (senile) of retina NOS Sense Organs 0.969 0.903 – 1.04 0.375 1090 3648 exclusion phecode
362.3 Other nondiabetic retinopathy Sense Organs 0.937 0.86 – 1.02 0.137 665 2486 exclusion phecode
362.31 Separation of retinal layers Sense Organs 0.87 0.75 – 1.01 0.0672 217 1223 exclusion phecode
362.4 Retinal vascular changes and abnomalities Sense Organs 0.991 0.89 – 1.1 0.866 422 1780 exclusion phecode
362.6 Peripheral retinal degenerations Sense Organs 0.975 0.851 – 1.12 0.715 242 1150 exclusion phecode
362.7 Hereditary retinal dystrophies Sense Organs 1.01 0.823 – 1.23 0.947 114 601 exclusion phecode
362.8 Retinal hemorrhage/ischemia Sense Organs 0.931 0.785 – 1.11 0.415 155 834 exclusion phecode
362.9 Retinal edema Sense Organs 0.909 0.783 – 1.05 0.209 219 1022 exclusion phecode
363
Chorioretinal inflammations, scars, and other
Chorioretinal inflammations, scars, and other disorders of choroid
 Sense Organs 0.884 0.776 – 1.01 0.063 279 1311 exclusion phecode
363.3 Chorioretinal scars Sense Organs 0.913 0.784 – 1.06 0.237 207 906 exclusion phecode
364 Corneal opacity and other disorders of cornea Sense Organs 0.972 0.888 – 1.06 0.546 588 2998 exclusion phecode
364.1 Corneal opacity Sense Organs 0.857 0.739 – 0.994 0.0417 230 1125 exclusion phecode
364.2 Corneal edema Sense Organs 0.737 0.56 – 0.97 0.0295 71 380 exclusion phecode
364.4 Corneal degenerations Sense Organs 0.876 0.753 – 1.02 0.0869 202 1199 exclusion phecode
364.41 Keratoconus Sense Organs 0.849 0.595 – 1.21 0.368 40 250 exclusion phecode
364.5 Corneal dystrophy Sense Organs 1.13 0.987 – 1.29 0.0769 274 1264 exclusion phecode
364.51 Fuchs' dystrophy Sense Organs 1.04 0.87 – 1.25 0.641 141 717 exclusion phecode
364.9 Cornea replaced by transplant Sense Organs 1.09 0.769 – 1.55 0.624 42 252 exclusion phecode
365 Glaucoma Sense Organs 0.975 0.917 – 1.04 0.416 1342 5629 exclusion phecode
365.1 Open-angle glaucoma Sense Organs 0.948 0.85 – 1.06 0.336 413 1859 exclusion phecode
365.11 Primary open angle glaucoma Sense Organs 0.988 0.853 – 1.14 0.874 231 1094 exclusion phecode
365.2 Primary angle-closure glaucoma Sense Organs 1.06 0.885 – 1.27 0.527 154 703 exclusion phecode
366 Cataract Sense Organs 1 0.959 – 1.04 0.968 4551 6649 exclusion phecode
366.1 Nonsenile Cataract Sense Organs 1.02 0.825 – 1.25 0.875 123 496 exclusion phecode
366.2 Senile cataract Sense Organs 0.997 0.951 – 1.04 0.888 3396 5846 exclusion phecode
367
Disorders of refraction and accommodation
Disorders of refraction and accommodation; blindness and low vision
 Sense Organs 0.992 0.956 – 1.03 0.651 5200 8262 exclusion phecode
367.1 Myopia Sense Organs 1 0.962 – 1.05 0.837 2997 7673 exclusion phecode
367.2 Astigmatism Sense Organs 0.999 0.953 – 1.05 0.96 2491 7296 exclusion phecode
367.8 Hypermetropia Sense Organs 0.985 0.923 – 1.05 0.659 1202 4357 exclusion phecode
367.9 Blindness and low vision Sense Organs 0.962 0.881 – 1.05 0.384 660 2886 exclusion phecode
368 Visual disturbances Sense Organs 1.03 0.99 – 1.08 0.136 2882 10222 exclusion phecode
368.1 Amblyopia Sense Organs 1.16 1.02 – 1.32 0.0193 319 1878 exclusion phecode
368.2 Diplopia and disorders of binocular vision Sense Organs 0.935 0.851 – 1.03 0.165 537 2926 exclusion phecode
368.3 Anisometropia Sense Organs 0.899 0.746 – 1.08 0.263 128 623 exclusion phecode
368.4 Visual field defects Sense Organs 0.974 0.891 – 1.06 0.557 589 2962 exclusion phecode
368.9 Subjective visual disturbances Sense Organs 0.942 0.86 – 1.03 0.206 575 2950 exclusion phecode
368.91 Psychophysical visual disturbances Sense Organs 0.911 0.688 – 1.21 0.518 59 299 exclusion phecode
369 Infection of the eye Sense Organs 1 0.952 – 1.06 0.913 1864 6743 exclusion phecode
369.2 Eye infection, viral Sense Organs 1.03 0.897 – 1.18 0.687 281 1325 exclusion phecode
369.5 Conjunctivitis, infectious Sense Organs 1 0.947 – 1.06 0.951 1625 6129 exclusion phecode
370 Keratitis Sense Organs 0.965 0.889 – 1.05 0.387 741 3342 exclusion phecode
370.1 Corneal ulcer Sense Organs 0.945 0.777 – 1.15 0.57 129 657 exclusion phecode
370.2 Superficial keratitis Sense Organs 0.927 0.815 – 1.05 0.246 310 1362 exclusion phecode
370.3 Keratoconjunctivitis Sense Organs 0.902 0.801 – 1.02 0.089 334 1557 exclusion phecode
370.31 Keratoconjunctivitis sicca Sense Organs 0.928 0.746 – 1.16 0.506 108 413 exclusion phecode
371 Inflammation of the eye Sense Organs 0.969 0.925 – 1.01 0.18 2568 7899 exclusion phecode
371.1 Uveitis, noninfectious or NOS Sense Organs 0.897 0.794 – 1.01 0.0814 312 1506 exclusion phecode
371.2 Conjunctivitis, noninfectious Sense Organs 0.955 0.868 – 1.05 0.34 529 2482 exclusion phecode
371.21 Allergic conjunctivitis Sense Organs 0.966 0.87 – 1.07 0.519 441 2079 exclusion phecode
371.3 Inflammation of eyelids Sense Organs 0.963 0.914 – 1.01 0.15 2000 6644 exclusion phecode
371.33 Noninfectious dermatoses of eyelid Sense Organs 0.825 0.636 – 1.07 0.149 77 314 exclusion phecode
372 Disorders of conjunctiva Sense Organs 1.06 0.962 – 1.16 0.256 602 2792 exclusion phecode
374 Other disorders of eyelids Sense Organs 1.02 0.958 – 1.08 0.608 1528 5809 exclusion phecode
374.1 Ectropion or entropion Sense Organs 0.979 0.835 – 1.15 0.794 182 980 exclusion phecode
374.2 Lagophthalmos Sense Organs 1.01 0.78 – 1.31 0.942 62 511 exclusion phecode
374.3 Ptosis of eyelid Sense Organs 0.962 0.878 – 1.05 0.397 563 2587 exclusion phecode
374.6 Dermatochalasis Sense Organs 0.994 0.909 – 1.09 0.904 605 2404 exclusion phecode
375 Disorders of lacrimal system Sense Organs 0.936 0.889 – 0.986 0.0129 2063 6316 exclusion phecode
375.1 Dry eyes Sense Organs 0.948 0.901 – 0.996 0.035 2295 6515 exclusion phecode
375.2 Epiphora Sense Organs 0.884 0.76 – 1.03 0.111 213 1074 exclusion phecode
376 Disorders of the orbit Sense Organs 0.968 0.787 – 1.19 0.758 103 817 exclusion phecode
377 Disorders of optic nerve and visual pathways Sense Organs 1.03 0.921 – 1.14 0.641 422 2208 exclusion phecode
377.1 Optic atrophy Sense Organs 0.974 0.825 – 1.15 0.757 173 800 exclusion phecode
377.3 Optic neuritis/neuropathy Sense Organs 1.05 0.913 – 1.21 0.501 246 1351 exclusion phecode
378
Strabismus and other disorders of binocular eye
Strabismus and other disorders of binocular eye movements
 Sense Organs 0.967 0.883 – 1.06 0.476 588 3030 exclusion phecode
378.1 Strabismus (not specified as paralytic) Sense Organs 0.947 0.847 – 1.06 0.333 401 2044 exclusion phecode
378.2 Nystagmus and other irregular eye movements Sense Organs 0.929 0.728 – 1.19 0.557 80 414 exclusion phecode
378.5 Paralytic strabismus Sense Organs 0.879 0.728 – 1.06 0.18 130 810 exclusion phecode
379 Other disorders of eye Sense Organs 0.979 0.935 – 1.02 0.354 2935 7292 exclusion phecode
379.1 Scleritis and episcleritis Sense Organs 0.913 0.73 – 1.14 0.425 106 460 exclusion phecode
379.2 Disorders of vitreous body Sense Organs 0.973 0.924 – 1.02 0.301 2184 5705 exclusion phecode
379.3 Aphakia and other disorders of lens Sense Organs 0.763 0.596 – 0.975 0.031 79 360 exclusion phecode
379.4 Anomalies of pupillary function Sense Organs 0.9 0.755 – 1.07 0.239 147 781 exclusion phecode
379.5 Disorders of iris and ciliary body Sense Organs 0.94 0.788 – 1.12 0.494 167 856 exclusion phecode
379.51 Pigmentary iris degeneration Sense Organs 1.15 0.772 – 1.71 0.496 41 161 exclusion phecode
379.9 Pain, swelling or discharge of eye Sense Organs 0.889 0.812 – 0.973 0.0104 602 2774 exclusion phecode
380 Disorders of external ear Sense Organs 1.02 0.958 – 1.08 0.559 1374 5775 exclusion phecode
380.1 Otitis externa Sense Organs 0.948 0.88 – 1.02 0.167 842 4226 exclusion phecode
380.4 Impacted cerumen Sense Organs 1.02 0.967 – 1.08 0.449 1695 6605 exclusion phecode
381 Otitis media and Eustachian tube disorders Sense Organs 0.995 0.948 – 1.04 0.825 2146 9301 exclusion phecode
381.1 Otitis media Sense Organs 1.02 0.96 – 1.08 0.584 1502 7670 exclusion phecode
381.11 Suppurative and unspecified otitis media Sense Organs 1.01 0.947 – 1.07 0.798 1266 6620 exclusion phecode
381.2 Eustachian tube disorders Sense Organs 0.962 0.897 – 1.03 0.274 1029 4938 exclusion phecode
381.3 Mastoiditis & related conditions Sense Organs 1.1 0.823 – 1.48 0.512 49 400 exclusion phecode
381.9 Otorrhea Sense Organs 0.932 0.776 – 1.12 0.449 135 900 exclusion phecode
382 Otalgia Sense Organs 1.01 0.943 – 1.08 0.748 1020 4989 exclusion phecode
383 Otosclerosis Sense Organs 0.844 0.603 – 1.18 0.325 37 321 exclusion phecode
384 Other disorders of tympanic membrane Sense Organs 1.06 0.914 – 1.24 0.425 213 1268 exclusion phecode
384.1 Myringitis Sense Organs 1.18 0.718 – 1.94 0.511 19 136 exclusion phecode
384.4 Perforation of tympanic membrane Sense Organs 1.09 0.917 – 1.29 0.33 164 986 exclusion phecode
385 Other disorders of middle ear and mastoid Sense Organs 1.04 0.864 – 1.26 0.663 125 1037 exclusion phecode
385.3 Cholesteatoma Sense Organs 1.02 0.779 – 1.32 0.907 59 615 exclusion phecode
385.5
Tympanosclerosis and middle ear disease related
Tympanosclerosis and middle ear disease related to otitis media
 Sense Organs 0.906 0.636 – 1.29 0.583 35 280 exclusion phecode
386
Vertiginous syndromes and other disorders of
Vertiginous syndromes and other disorders of vestibular system
 Sense Organs 1 0.934 – 1.08 0.931 1000 4550 exclusion phecode
386.1 Meniere's disease Sense Organs 1.08 0.893 – 1.3 0.442 141 838 exclusion phecode
386.2 Peripheral or central vertigo Sense Organs 1.02 0.947 – 1.1 0.569 869 3877 exclusion phecode
386.21 Central origin vertigo Sense Organs 1.04 0.951 – 1.14 0.392 643 2990 exclusion phecode
386.3 Labyrinthitis Sense Organs 1.02 0.94 – 1.1 0.65 769 3697 exclusion phecode
386.9
Dizziness and giddiness (Light-headedness and
Dizziness and giddiness (Light-headedness and vertigo)
 Sense Organs 1.05 1.01 – 1.09 0.0242 3698 9384 exclusion phecode
388 Other disorders of ear Sense Organs 1.01 0.911 – 1.12 0.872 475 2514 exclusion phecode
389 Hearing loss Sense Organs 1.01 0.972 – 1.05 0.542 3684 9485 exclusion phecode
389.1 Sensorineural hearing loss Sense Organs 1 0.952 – 1.05 0.953 2116 7345 exclusion phecode
389.2 Conductive hearing loss Sense Organs 1.01 0.903 – 1.14 0.835 344 2248 exclusion phecode
389.3 Degenerative and vascular disorders of ear Sense Organs 0.842 0.679 – 1.04 0.116 115 506 exclusion phecode
389.4 Tinnitus Sense Organs 0.996 0.934 – 1.06 0.9 1165 5817 exclusion phecode
389.5 Disorders of acoustic nerve Sense Organs 0.954 0.715 – 1.27 0.75 59 281 exclusion phecode
394 Rheumatic disease of the heart valves Circulatory System 1.04 0.969 – 1.12 0.273 1018 3414 exclusion phecode
394.1 Mitral valve stenosis and aortic valve stenosis Circulatory System 1.06 0.923 – 1.22 0.393 261 896 exclusion phecode
394.2 Mitral valve disease Circulatory System 0.989 0.87 – 1.12 0.867 320 1114 exclusion phecode
394.3 Aortic valve disease Circulatory System 1.14 0.937 – 1.38 0.191 142 412 exclusion phecode
394.4 Acute rheumatic heart disease Circulatory System 0.795 0.53 – 1.19 0.27 31 117 exclusion phecode
394.7 Disease of tricuspid valve Circulatory System 1.03 0.92 – 1.16 0.574 410 1318 exclusion phecode
395 Heart valve disorders Circulatory System 1.11 1.06 – 1.17 3.55e-05 2290 7078 exclusion phecode
395.1 Nonrheumatic mitral valve disorders Circulatory System 1.09 1.02 – 1.16 0.00856 1244 5088 exclusion phecode
395.2 Nonrheumatic aortic valve disorders Circulatory System 1.14 1.07 – 1.21 6.91e-05 1365 4347 exclusion phecode
395.3 Nonrheumatic tricuspid valve disorders Circulatory System 1.1 0.968 – 1.24 0.15 348 1216 exclusion phecode
395.4 Nonrheumatic pulmonary valve disorders Circulatory System 0.991 0.723 – 1.36 0.953 61 302 exclusion phecode
395.6 Heart valve replaced Circulatory System 1.1 1.01 – 1.2 0.0225 782 2634 exclusion phecode
396 Abnormal heart sounds Circulatory System 1.09 1.04 – 1.14 0.000504 2308 8637 exclusion phecode
401 Hypertension Circulatory System 1.04 0.999 – 1.09 0.055 8361 5087 exclusion phecode
401.1 Essential hypertension Circulatory System 1.04 0.999 – 1.09 0.0583 8303 5086 exclusion phecode
401.2 Hypertensive heart and/or renal disease Circulatory System 1.09 1.03 – 1.16 0.00559 2188 3040 exclusion phecode
401.21 Hypertensive heart disease Circulatory System 1.17 1.06 – 1.29 0.00167 637 1333 exclusion phecode
401.22 Hypertensive chronic kidney disease Circulatory System 1.07 1 – 1.15 0.0395 1562 2697 exclusion phecode
401.3 Other hypertensive complications Circulatory System 1.1 1.03 – 1.17 0.00289 1657 3347 exclusion phecode
411 Ischemic Heart Disease Circulatory System 1.17 1.12 – 1.22 1.19e-12 4470 6889 exclusion phecode
411.1 Unstable angina (intermediate coronary syndrome) Circulatory System 1.29 1.18 – 1.41 1.89e-08 777 2118 exclusion phecode
411.2 Myocardial infarction Circulatory System 1.17 1.1 – 1.24 1.55e-07 1786 4804 exclusion phecode
411.3 Angina pectoris Circulatory System 1.17 1.11 – 1.25 1.36e-07 1717 4085 exclusion phecode
411.4 Coronary atherosclerosis Circulatory System 1.17 1.12 – 1.23 1.7e-12 3980 6216 exclusion phecode
411.41 Aneurysm and dissection of heart Circulatory System 1.21 0.969 – 1.52 0.0918 118 364 exclusion phecode
411.8
Other chronic ischemic heart disease
Other chronic ischemic heart disease, unspecified
 Circulatory System 1.19 1.14 – 1.25 6.26e-13 3321 5756 exclusion phecode
411.9
Other acute and subacute forms of ischemic
Other acute and subacute forms of ischemic heart disease
 Circulatory System 1.05 0.92 – 1.2 0.462 312 1065 exclusion phecode
414 Other forms of chronic heart disease Circulatory System 1.19 1.12 – 1.26 1.04e-09 1980 5010 exclusion phecode
414.2 ASCVD Circulatory System 1.15 1.03 – 1.27 0.0099 526 1717 exclusion phecode
415 Pulmonary heart disease Circulatory System 1.04 0.986 – 1.1 0.146 1613 8024 exclusion phecode
415.1 Acute pulmonary heart disease Circulatory System 1.05 0.974 – 1.13 0.197 785 5035 exclusion phecode
415.11 Pulmonary embolism and infarction, acute Circulatory System 1.05 0.971 – 1.13 0.233 780 5020 exclusion phecode
415.2 Chronic pulmonary heart disease Circulatory System 1.05 0.98 – 1.12 0.166 1082 4934 exclusion phecode
415.21 Primary pulmonary hypertension Circulatory System 1.01 0.908 – 1.13 0.841 444 1976 exclusion phecode
416 Cardiomegaly Circulatory System 0.922 0.852 – 0.997 0.0429 802 3531 exclusion phecode
418 Nonspecific chest pain Circulatory System 1.02 0.987 – 1.06 0.212 6795 6619 exclusion phecode
418.1 Precordial pain Circulatory System 1.07 0.994 – 1.15 0.0732 993 2806 exclusion phecode
420 Carditis Circulatory System 1.06 0.983 – 1.14 0.133 961 4307 exclusion phecode
420.1 Myocarditis Circulatory System 0.9 0.672 – 1.2 0.478 61 292 exclusion phecode
420.2 Pericarditis Circulatory System 1 0.908 – 1.11 0.958 491 2218 exclusion phecode
420.21 Acute pericarditis Circulatory System 0.993 0.796 – 1.24 0.954 105 463 exclusion phecode
420.22 Chronic pericarditis Circulatory System 0.898 0.678 – 1.19 0.455 77 288 exclusion phecode
420.3 Endocarditis Circulatory System 1.04 0.938 – 1.15 0.475 500 2109 exclusion phecode
425 Cardiomyopathy Circulatory System 1.1 1.03 – 1.17 0.00264 1345 5452 exclusion phecode
425.1 Primary/intrinsic cardiomyopathies Circulatory System 1.09 1.02 – 1.16 0.00785 1298 5241 exclusion phecode
425.11 Hypertrophic obstructive cardiomyopathy Circulatory System 0.982 0.812 – 1.19 0.849 140 589 exclusion phecode
425.12 Other hypertrophic cardiomyopathy Circulatory System 1 0.817 – 1.23 0.969 118 531 exclusion phecode
425.2 Secondary/extrinsic cardiomyopathies Circulatory System 1.05 0.903 – 1.22 0.532 216 878 exclusion phecode
425.8 Other cardiomyopathy Circulatory System 0.977 0.713 – 1.34 0.885 55 217 exclusion phecode
426 Cardiac conduction disorders Circulatory System 1.07 1.02 – 1.12 0.00332 6102 4601 exclusion phecode
426.2 Atrioventricular [AV] block Circulatory System 1.08 0.999 – 1.17 0.0536 1199 1856 exclusion phecode
426.21 First degree AV block Circulatory System 1.07 0.977 – 1.17 0.141 835 1421 exclusion phecode
426.22 Mobitz II AV block Circulatory System 1.04 0.747 – 1.45 0.809 49 105 exclusion phecode
426.23 Second degree AV block Circulatory System 1.1 0.901 – 1.34 0.35 145 354 exclusion phecode
426.24 Atrioventricular block, complete Circulatory System 1.09 0.941 – 1.26 0.25 320 609 exclusion phecode
426.25 Other heart block Circulatory System 1 0.789 – 1.27 0.994 138 283 exclusion phecode
426.3 Bundle branch block Circulatory System 1.11 1.03 – 1.2 0.00433 1321 2280 exclusion phecode
426.31 Right bundle branch block Circulatory System 1.08 0.988 – 1.18 0.0918 804 1736 exclusion phecode
426.32 Left bundle branch block Circulatory System 1.06 0.957 – 1.17 0.264 599 1317 exclusion phecode
426.4 Anomalous atrioventricular excitation Circulatory System 1.11 0.741 – 1.67 0.604 30 130 exclusion phecode
426.7 Abnormal electrocardiogram [ECG] [EKG] Circulatory System 1.07 1.02 – 1.12 0.00381 5522 4574 exclusion phecode
426.8 Other cardiac conduction disorders Circulatory System 1.06 0.946 – 1.19 0.317 427 1175 exclusion phecode
426.9 Cardiac pacemaker/device in situ Circulatory System 1.1 1.01 – 1.19 0.0293 973 1895 exclusion phecode
426.91 Cardiac pacemaker in situ Circulatory System 1.08 0.977 – 1.19 0.131 632 1308 exclusion phecode
426.92 Cardiac defibrillator in situ Circulatory System 1.08 0.975 – 1.2 0.137 563 1203 exclusion phecode
427 Cardiac dysrhythmias Circulatory System 1.07 1.02 – 1.11 0.00233 7474 4699 exclusion phecode
427.1 Paroxysmal tachycardia, unspecified Circulatory System 1.11 1.04 – 1.2 0.00222 1372 3055 exclusion phecode
427.11 Paroxysmal supraventricular tachycardia Circulatory System 1.08 0.989 – 1.17 0.0884 801 2352 exclusion phecode
427.12 Paroxysmal ventricular tachycardia Circulatory System 1.14 1.04 – 1.25 0.00525 785 1684 exclusion phecode
427.2 Atrial fibrillation and flutter Circulatory System 1.09 1.02 – 1.16 0.00686 2580 3157 exclusion phecode
427.21 Atrial fibrillation Circulatory System 1.09 1.02 – 1.16 0.00812 2528 3098 exclusion phecode
427.22 Atrial flutter Circulatory System 1.05 0.967 – 1.15 0.229 1005 1763 exclusion phecode
427.3 Other specified cardiac dysrhythmias Circulatory System 1.08 1.03 – 1.13 0.0011 4314 4586 exclusion phecode
427.4 Cardiac arrest and ventricular fibrillation Circulatory System 1.08 0.946 – 1.23 0.263 334 895 exclusion phecode
427.41 Ventricular fibrillation and flutter Circulatory System 1.17 0.955 – 1.43 0.13 159 402 exclusion phecode
427.42 Cardiac arrest Circulatory System 1.06 0.918 – 1.23 0.415 248 700 exclusion phecode
427.5 Arrhythmia (cardiac) NOS Circulatory System 1.06 1.01 – 1.11 0.0262 3315 4560 exclusion phecode
427.6 Premature beats Circulatory System 1.09 1.02 – 1.17 0.0116 1404 2828 exclusion phecode
427.61 Supraventricular premature beats Circulatory System 1.06 0.94 – 1.2 0.337 414 1089 exclusion phecode
427.7 Tachycardia NOS Circulatory System 1.08 1.02 – 1.14 0.00601 2439 4614 exclusion phecode
427.8 Sinoatrial node dysfunction (Bradycardia) Circulatory System 1.03 0.925 – 1.14 0.604 573 1211 exclusion phecode
427.9 Palpitations Circulatory System 1.07 1.01 – 1.12 0.0151 2573 4541 exclusion phecode
428 Congestive heart failure; nonhypertensive Circulatory System 1.1 1.04 – 1.16 0.000385 2571 4637 exclusion phecode
428.1 Congestive heart failure (CHF) NOS Circulatory System 1.11 1.06 – 1.18 0.000104 2247 4357 exclusion phecode
428.2 Heart failure NOS Circulatory System 1.09 1.03 – 1.16 0.00156 2220 4196 exclusion phecode
428.3
Heart failure with reduced EF [Systolic or
Heart failure with reduced EF [Systolic or combined heart failure]
 Circulatory System 1.18 1.1 – 1.26 6.03e-06 1260 2799 exclusion phecode
428.4
Heart failure with preserved EF [Diastolic
Heart failure with preserved EF [Diastolic heart failure]
 Circulatory System 1.05 0.979 – 1.13 0.164 1133 2567 exclusion phecode
429
Ill-defined descriptions and complications of
Ill-defined descriptions and complications of heart disease
 Circulatory System 1.08 1.04 – 1.12 4.47e-05 6273 6625 exclusion phecode
429.1 Heart transplant/surgery Circulatory System 1.11 1.02 – 1.21 0.0132 836 2235 exclusion phecode
429.2 Abnormal function study of cardiovascular system Circulatory System 1.08 1.03 – 1.13 0.00127 3591 6004 exclusion phecode
429.3 Symptoms involving cardiovascular system Circulatory System 1.09 1.05 – 1.13 2.81e-05 4906 6618 exclusion phecode
429.9 Cardiac complications, not elsewhere classified Circulatory System 1.11 0.993 – 1.24 0.0655 435 1283 exclusion phecode
430 Intracranial hemorrhage Circulatory System 1.1 0.973 – 1.23 0.132 330 2154 exclusion phecode
430.1 Subarachnoid hemorrhage Circulatory System 1.31 1.05 – 1.63 0.0151 113 660 exclusion phecode
430.2 Intracerebral hemorrhage Circulatory System 1.13 0.946 – 1.35 0.179 151 947 exclusion phecode
430.3 Subdural hemorrhage Circulatory System 1.09 0.897 – 1.31 0.401 121 766 exclusion phecode
433 Cerebrovascular disease Circulatory System 1.09 1.04 – 1.14 0.000306 2535 8563 exclusion phecode
433.1 Occlusion and stenosis of precerebral arteries Circulatory System 1.11 1.04 – 1.19 0.00205 1149 4393 exclusion phecode
433.11
Occlusion of cerebral arteries, with cerebral
Occlusion of cerebral arteries, with cerebral infarction
 Circulatory System 1.2 1.01 – 1.41 0.034 177 719 exclusion phecode
433.12 Cerebral atherosclerosis Circulatory System 1.32 0.96 – 1.8 0.0875 58 252 exclusion phecode
433.2 Occlusion of cerebral arteries Circulatory System 1.11 1.03 – 1.18 0.00281 1130 5816 exclusion phecode
433.21
Cerebral artery occlusion, with cerebral
Cerebral artery occlusion, with cerebral infarction
 Circulatory System 1.1 1.03 – 1.18 0.00398 1093 5641 exclusion phecode
433.3 Cerebral ischemia Circulatory System 1.09 1.02 – 1.15 0.00736 1372 6109 exclusion phecode
433.31 Transient cerebral ischemia Circulatory System 1.07 1 – 1.14 0.0356 1202 5543 exclusion phecode
433.5 Cerebral aneurysm Circulatory System 1.05 0.884 – 1.24 0.59 156 1196 exclusion phecode
433.6 Acute, but ill-defined cerebrovascular disease Circulatory System 1.11 0.979 – 1.25 0.104 365 1344 exclusion phecode
433.8 Late effects of cerebrovascular disease Circulatory System 1.08 0.969 – 1.21 0.163 428 1835 exclusion phecode
440 Atherosclerosis Circulatory System 1.07 1.01 – 1.13 0.0241 1639 4657 exclusion phecode
440.1 Atherosclerosis of renal artery Circulatory System 1.09 0.902 – 1.32 0.372 145 501 exclusion phecode
440.2 Atherosclerosis of the extremities Circulatory System 1.04 0.967 – 1.12 0.303 1040 3353 exclusion phecode
440.21
Atherosclerosis of native arteries of the
Atherosclerosis of native arteries of the extremities with ulceration or gangrene
 Circulatory System 1.2 1.02 – 1.4 0.0255 215 825 exclusion phecode
440.22
Atherosclerosis of native arteries of the
Atherosclerosis of native arteries of the extremities with intermittent claudication
 Circulatory System 1.03 0.943 – 1.11 0.559 750 2505 exclusion phecode
440.9 Atherosclerosis of aorta Circulatory System 1.13 1.03 – 1.24 0.0118 605 1881 exclusion phecode
441 Vascular insufficiency of intestine Circulatory System 0.928 0.808 – 1.07 0.294 280 1246 exclusion phecode
441.1 Acute vascular insufficiency of intestine Circulatory System 0.963 0.791 – 1.17 0.703 138 594 exclusion phecode
441.2 Chronic vascular insufficiency of intestine Circulatory System 0.786 0.614 – 1.01 0.0557 79 377 exclusion phecode
442 Other aneurysm Circulatory System 1.07 1.01 – 1.14 0.0263 1515 4903 exclusion phecode
442.1 Aortic aneurysm Circulatory System 1.08 1.01 – 1.16 0.0209 1239 3794 exclusion phecode
442.11 Abdominal aortic aneurysm Circulatory System 1.13 1.03 – 1.23 0.00677 664 2393 exclusion phecode
442.2 Aneurysm of iliac artery Circulatory System 1.22 0.985 – 1.51 0.0689 108 441 exclusion phecode
442.3 Aneurysm of artery of lower extremity Circulatory System 1.18 0.938 – 1.5 0.156 99 388 exclusion phecode
442.4 Arterial dissection Circulatory System 1.04 0.844 – 1.29 0.697 109 392 exclusion phecode
442.8 Aneurysm of other specified artery Circulatory System 1.05 0.895 – 1.23 0.544 197 903 exclusion phecode
443 Peripheral vascular disease Circulatory System 1.09 1.03 – 1.15 0.00455 1711 5838 exclusion phecode
443.1 Raynaud's syndrome Circulatory System 1 0.888 – 1.13 0.958 325 1722 exclusion phecode
443.7
Peripheral angiopathy in diseases classified
Peripheral angiopathy in diseases classified elsewhere
 Circulatory System 1.12 0.951 – 1.33 0.171 189 806 exclusion phecode
443.8 Other specified peripheral vascular diseases Circulatory System 1.08 1.02 – 1.15 0.0125 1377 5219 exclusion phecode
443.9 Peripheral vascular disease, unspecified Circulatory System 1.09 1.03 – 1.17 0.00524 1384 4512 exclusion phecode
444 Arterial embolism and thrombosis Circulatory System 1.07 0.964 – 1.18 0.211 475 2059 exclusion phecode
444.1
Arterial embolism and thrombosis of lower
Arterial embolism and thrombosis of lower extremity artery
 Circulatory System 1.07 0.909 – 1.26 0.406 187 784 exclusion phecode
444.2 Embolism and thrombosis of abdominal aorta Circulatory System 1.29 1.01 – 1.65 0.0393 91 354 exclusion phecode
446 Polyarteritis nodosa and allied conditions Circulatory System 1.05 0.909 – 1.21 0.513 239 1122 exclusion phecode
446.4 Wegener's granulomatosis Circulatory System 1.24 0.903 – 1.71 0.183 44 260 exclusion phecode
446.5 Giant cell arteritis Circulatory System 0.928 0.672 – 1.28 0.648 41 159 exclusion phecode
446.9 Arteritis NOS Circulatory System 0.955 0.798 – 1.14 0.62 152 757 exclusion phecode
447 Other disorders of arteries and arterioles Circulatory System 1.06 1 – 1.13 0.0438 1545 5305 exclusion phecode
447.1 Stricture of artery Circulatory System 1.04 0.917 – 1.19 0.511 308 1162 exclusion phecode
447.7 Aortic ectasia Circulatory System 1.01 0.918 – 1.11 0.832 567 1949 exclusion phecode
448 Disease of capillaries Circulatory System 1.04 0.952 – 1.14 0.38 640 2943 exclusion phecode
450 Noninfectious disorders of lymphatic channels Circulatory System 1.03 0.954 – 1.11 0.445 750 5831 exclusion phecode
451 Phlebitis and thrombophlebitis Circulatory System 1.01 0.903 – 1.14 0.818 380 1543 exclusion phecode
451.2
Phlebitis and thrombophlebitis of lower
Phlebitis and thrombophlebitis of lower extremities
 Circulatory System 0.977 0.805 – 1.19 0.818 125 536 exclusion phecode
452 Other venous embolism and thrombosis Circulatory System 1 0.949 – 1.06 0.982 1929 6162 exclusion phecode
452.1 Iatrogenic pulmonary embolism and infarction Circulatory System 1.01 0.833 – 1.23 0.913 138 589 exclusion phecode
452.2 Deep vein thrombosis [DVT] Circulatory System 1.01 0.952 – 1.08 0.651 1220 5513 exclusion phecode
452.8 Postphlebitic syndrome Circulatory System 0.892 0.68 – 1.17 0.412 52 295 exclusion phecode
453 Chronic venous hypertension Circulatory System 1 0.825 – 1.22 0.967 135 485 exclusion phecode
454 Varicose veins Circulatory System 0.94 0.884 – 0.999 0.0473 1395 5178 exclusion phecode
454.1 Varicose veins of lower extremity Circulatory System 0.939 0.881 – 1 0.0562 1254 4497 exclusion phecode
454.11 Varicose veins of lower extremity, symptomtic Circulatory System 0.918 0.85 – 0.991 0.0282 875 3185 exclusion phecode
455 Hemorrhoids Circulatory System 1.05 1 – 1.09 0.0507 3347 6402 exclusion phecode
456 Chronic venous insufficiency [CVI] Circulatory System 0.978 0.925 – 1.03 0.44 1776 5321 exclusion phecode
457
Encounter for long-term (current) use of
Encounter for long-term (current) use of anticoagulants, antithrombotics, aspirin
 Circulatory System 1.13 1.05 – 1.21 0.00137 1063 3156 exclusion phecode
457.2
Encounter for long-term (current) use of
Encounter for long-term (current) use of antiplatelets/antithrombotics
 Circulatory System 1.17 0.992 – 1.39 0.0619 181 671 exclusion phecode
457.3 Encounter for long-term (current) use of aspirin Circulatory System 1.12 1.04 – 1.2 0.00403 1001 3034 exclusion phecode
458 Hypotension Circulatory System 1.07 1.02 – 1.12 0.00763 2656 7542 exclusion phecode
458.1 Orthostatic hypotension Circulatory System 0.993 0.916 – 1.08 0.867 798 3159 exclusion phecode
458.2 Iatrogenic hypotension Circulatory System 1.04 0.945 – 1.13 0.45 610 2591 exclusion phecode
458.9 Hypotension NOS Circulatory System 1.06 1.01 – 1.11 0.0176 2421 7294 exclusion phecode
459 Other disorders of circulatory system Circulatory System 1.05 1 – 1.09 0.0292 3572 8176 exclusion phecode
459.1 Hemorrhage NOS Circulatory System 1 0.901 – 1.11 0.988 460 2060 exclusion phecode
459.7 Blood vessel replaced Circulatory System 1.01 0.929 – 1.11 0.744 629 2855 exclusion phecode
459.9 Circulatory disease NEC Circulatory System 1.06 1.01 – 1.11 0.00996 3102 7861 exclusion phecode
464 Acute sinusitis Respiratory 0.98 0.937 – 1.03 0.394 2902 6370 exclusion phecode
465
Acute upper respiratory infections of multiple
Acute upper respiratory infections of multiple or unspecified sites
 Respiratory 0.977 0.942 – 1.01 0.216 5684 7132 exclusion phecode
465.2 Acute pharyngitis Respiratory 0.987 0.944 – 1.03 0.577 3103 6319 exclusion phecode
465.4 Acute laryngitis and tracheitis Respiratory 0.919 0.791 – 1.07 0.267 233 883 exclusion phecode
470 Septal Deviations/Turbinate Hypertrophy Respiratory 0.939 0.866 – 1.02 0.133 731 3576 exclusion phecode
471 Nasal polyps Respiratory 1.04 0.894 – 1.2 0.644 211 1294 exclusion phecode
472 Chronic pharyngitis and nasopharyngitis Respiratory 0.965 0.897 – 1.04 0.329 1007 3756 exclusion phecode
473 Diseases of the larynx and vocal cords Respiratory 0.962 0.9 – 1.03 0.245 1139 5243 exclusion phecode
473.1 Chronic laryngitis Respiratory 1.13 0.789 – 1.62 0.503 38 151 exclusion phecode
473.3 Paralysis/spasm of vocal cords or larynx Respiratory 1.04 0.895 – 1.2 0.623 212 1267 exclusion phecode
473.4 Voice disturbance Respiratory 0.995 0.925 – 1.07 0.904 897 4476 exclusion phecode
474 Acute and chronic tonsillitis Respiratory 0.941 0.839 – 1.06 0.298 395 1551 exclusion phecode
474.1 Acute tonsillitis Respiratory 1.03 0.852 – 1.25 0.752 149 577 exclusion phecode
474.2 Chronic tonsillitis and adenoiditis Respiratory 0.919 0.805 – 1.05 0.206 298 1226 exclusion phecode
475 Chronic sinusitis Respiratory 0.988 0.938 – 1.04 0.641 2148 5818 exclusion phecode
475.9 Postnasal drip Respiratory 0.929 0.842 – 1.03 0.147 546 2097 exclusion phecode
476 Allergic rhinitis Respiratory 0.969 0.933 – 1.01 0.11 5422 5899 exclusion phecode
477 Epistaxis or throat hemorrhage Respiratory 1.09 0.995 – 1.19 0.063 662 2449 exclusion phecode
478 Throat pain Respiratory 0.978 0.828 – 1.15 0.791 194 854 exclusion phecode
479 Other upper respiratory disease Respiratory 0.985 0.94 – 1.03 0.542 2670 5882 exclusion phecode
480 Pneumonia Respiratory 1.07 1.02 – 1.12 0.00264 2876 8632 exclusion phecode
480.1 Bacterial pneumonia Respiratory 1.12 1.02 – 1.22 0.0141 666 2867 exclusion phecode
480.11 Pneumococcal pneumonia Respiratory 1.14 1.01 – 1.29 0.0295 350 1415 exclusion phecode
480.12 Pseudomonal pneumonia Respiratory 1.18 0.922 – 1.52 0.186 84 348 exclusion phecode
480.13 MRSA pneumonia Respiratory 0.887 0.666 – 1.18 0.416 62 329 exclusion phecode
480.2 Viral pneumonia Respiratory 1.04 0.869 – 1.25 0.656 135 563 exclusion phecode
480.3 Pneumonia due to fungus (mycoses) Respiratory 1.26 0.991 – 1.59 0.0599 91 408 exclusion phecode
480.5 Bronchopneumonia and lung abscess Respiratory 0.921 0.705 – 1.2 0.546 66 331 exclusion phecode
481 Influenza Respiratory 0.986 0.912 – 1.07 0.729 819 3609 exclusion phecode
483 Acute bronchitis and bronchiolitis Respiratory 0.989 0.941 – 1.04 0.646 2208 7224 exclusion phecode
495 Asthma Respiratory 1.01 0.971 – 1.06 0.573 3214 8551 exclusion phecode
495.1 Chronic obstructive asthma Respiratory 0.971 0.838 – 1.13 0.701 216 1048 exclusion phecode
495.11 Chronic obstructive asthma with exacerbation Respiratory 1.15 0.855 – 1.55 0.354 61 262 exclusion phecode
495.2 Asthma with exacerbation Respiratory 1 0.93 – 1.08 0.949 860 4185 exclusion phecode
496 Chronic airway obstruction Respiratory 1.03 0.98 – 1.09 0.227 1895 7244 exclusion phecode
496.1 Emphysema Respiratory 1.03 0.959 – 1.12 0.384 795 4984 exclusion phecode
496.2 Chronic bronchitis Respiratory 1.05 0.992 – 1.11 0.0911 1460 6804 exclusion phecode
496.21 Obstructive chronic bronchitis Respiratory 1.08 1.01 – 1.14 0.0187 1320 6517 exclusion phecode
496.3 Bronchiectasis Respiratory 1.12 0.981 – 1.29 0.0913 266 1542 exclusion phecode
497 Bronchitis Respiratory 0.98 0.918 – 1.05 0.558 1136 5200 exclusion phecode
498 Acute bronchospasm Respiratory 0.872 0.765 – 0.994 0.0408 300 1311 exclusion phecode
499 Cystic fibrosis Respiratory 0.918 0.718 – 1.17 0.495 85 493 exclusion phecode
500 Lung disease due to external agents Respiratory 0.899 0.781 – 1.04 0.139 249 1389 exclusion phecode
500.1 Extrinsic allergic alveolitis Respiratory 0.943 0.681 – 1.31 0.725 45 209 exclusion phecode
500.2 Pneumoconiosis Respiratory 1.07 0.778 – 1.46 0.687 43 196 exclusion phecode
501 Pneumonitis due to inhalation of food or vomitus Respiratory 1.07 0.94 – 1.21 0.308 296 1561 exclusion phecode
502 Postinflammatory pulmonary fibrosis Respiratory 0.978 0.877 – 1.09 0.697 404 2027 exclusion phecode
503 Pulmonary congestion and hypostasis Respiratory 1.09 0.992 – 1.2 0.0709 560 2202 exclusion phecode
504 Other alveolar and parietoalveolar pneumonopathy Respiratory 0.995 0.876 – 1.13 0.941 300 1499 exclusion phecode
504.1 Idiopathic fibrosing alveolitis Respiratory 1.01 0.851 – 1.19 0.924 162 795 exclusion phecode
505 Other pulmonary inflamation or edema Respiratory 1.04 0.972 – 1.12 0.243 1047 4094 exclusion phecode
506 Empyema and pneumothorax Respiratory 1.08 1.01 – 1.14 0.0188 1346 6098 exclusion phecode
507 Pleurisy; pleural effusion Respiratory 1.02 0.963 – 1.08 0.482 1481 6388 exclusion phecode
508
Pulmonary collapse; interstitial and
Pulmonary collapse; interstitial and compensatory emphysema
 Respiratory 1.05 0.98 – 1.12 0.172 1156 5590 exclusion phecode
509 Respiratory failure, insufficiency, arrest Respiratory 1.12 1.06 – 1.17 2.61e-05 2099 7151 exclusion phecode
509.1 Respiratory failure Respiratory 1.04 0.972 – 1.12 0.235 988 4731 exclusion phecode
509.2 Respiratory insufficiency Respiratory 1.1 1.01 – 1.2 0.0335 644 2911 exclusion phecode
509.3
Pulmonary insufficiency or respiratory failure
Pulmonary insufficiency or respiratory failure following trauma and surgery
 Respiratory 1.07 0.998 – 1.15 0.0582 974 4026 exclusion phecode
509.8
Dependence on respirator [Ventilator] or
Dependence on respirator [Ventilator] or supplemental oxygen
 Respiratory 1.13 1.05 – 1.22 0.00106 893 4261 exclusion phecode
510 Other diseases of lung Respiratory 1 0.959 – 1.05 0.947 2763 9362 exclusion phecode
510.2 Lung transplant Respiratory 0.972 0.793 – 1.19 0.783 122 468 exclusion phecode
512 Other symptoms of respiratory system Respiratory 1.02 0.986 – 1.06 0.227 8794 4672 exclusion phecode
512.1 Wheezing Respiratory 1.02 0.943 – 1.11 0.576 886 2376 exclusion phecode
512.2 Painful respiration Respiratory 1 0.937 – 1.07 0.95 1323 3590 exclusion phecode
512.3 Abnormal chest sounds Respiratory 1 0.839 – 1.2 0.968 204 472 exclusion phecode
512.7 Shortness of breath Respiratory 1.05 1.01 – 1.1 0.0215 5289 4648 exclusion phecode
512.8 Cough Respiratory 0.998 0.957 – 1.04 0.924 5429 4671 exclusion phecode
512.9 Other dyspnea Respiratory 1.03 0.992 – 1.08 0.114 5522 4661 exclusion phecode
513 Respiratory abnormalities Respiratory 1.03 0.992 – 1.07 0.129 6244 7220 exclusion phecode
513.3 Hypoventilation Respiratory 0.972 0.884 – 1.07 0.568 570 2067 exclusion phecode
513.31 Apnea Respiratory 1.05 0.919 – 1.2 0.474 286 1102 exclusion phecode
513.32 Orthopnea Respiratory 0.866 0.72 – 1.04 0.127 158 498 exclusion phecode
513.4 Hyperventilation Respiratory 1.05 0.921 – 1.2 0.458 303 997 exclusion phecode
513.8 Disorders of diaphragm Respiratory 1.05 0.858 – 1.27 0.659 128 598 exclusion phecode
514 Abnormal findings examination of lungs Respiratory 1 0.955 – 1.05 0.911 2124 9435 exclusion phecode
514.1
Abnormal results of function study of pulmonary
Abnormal results of function study of pulmonary system
 Respiratory 1.06 0.888 – 1.27 0.512 157 787 exclusion phecode
514.2 Solitary pulmonary nodule Respiratory 1 0.939 – 1.06 0.996 1186 7404 exclusion phecode
516 Abnormal sputum Respiratory 1.05 0.941 – 1.18 0.369 380 2230 exclusion phecode
516.1 Hemoptysis Respiratory 1.07 0.942 – 1.21 0.31 315 1838 exclusion phecode
519
Other diseases of respiratory system, not
Other diseases of respiratory system, not elsewhere classified
 Respiratory 1.04 1 – 1.09 0.0442 3010 10075 exclusion phecode
519.1 Tracheostomy complications Respiratory 1.13 0.862 – 1.48 0.378 58 508 exclusion phecode
519.2 Respiratory complications Respiratory 0.964 0.832 – 1.12 0.627 212 1065 exclusion phecode
519.8 Other diseases of respiratory system, NEC Respiratory 0.993 0.915 – 1.08 0.871 699 4241 exclusion phecode
519.9
Symptoms involving respiratory system and other
Symptoms involving respiratory system and other chest symptoms
 Respiratory 1.07 1.02 – 1.12 0.00848 2277 8924 exclusion phecode
520 Disorders of tooth development Digestive 0.914 0.731 – 1.14 0.432 89 964 exclusion phecode
520.1 Hereditary disturbances in tooth structure Digestive 0.871 0.645 – 1.18 0.367 44 475 exclusion phecode
520.2 Disturbances in tooth eruption Digestive 0.987 0.701 – 1.39 0.941 42 509 exclusion phecode
521 Diseases of hard tissues of teeth Digestive 1.01 0.893 – 1.15 0.861 292 2458 exclusion phecode
521.1 Dental caries Digestive 0.999 0.878 – 1.14 0.985 269 2296 exclusion phecode
521.2 Dental abrasion, erosion and attrition Digestive 1.21 0.724 – 2.01 0.472 20 124 exclusion phecode
522 Diseases of pulp and periapical tissues Digestive 1.05 0.916 – 1.21 0.48 253 1517 exclusion phecode
522.5 Periapical abscess Digestive 0.996 0.863 – 1.15 0.957 232 1298 exclusion phecode
523 Gingival and periodontal diseases Digestive 0.975 0.864 – 1.1 0.685 306 2003 exclusion phecode
523.1 Gingivitis Digestive 0.725 0.548 – 0.959 0.0241 65 395 exclusion phecode
523.3 Periodontitis (acute or chronic) Digestive 1.02 0.868 – 1.2 0.802 166 1006 exclusion phecode
523.31 Acute periodontitis Digestive 0.979 0.82 – 1.17 0.818 144 843 exclusion phecode
523.32 Chronic periodontitis Digestive 1.07 0.768 – 1.49 0.694 43 317 exclusion phecode
524 Dentofacial anomalies, including malocclusion Digestive 0.918 0.707 – 1.19 0.522 65 780 exclusion phecode
524.3 Anomalies of tooth position/malocclusion Digestive 0.856 0.612 – 1.2 0.363 37 443 exclusion phecode
525
Other diseases of the teeth and supporting
Other diseases of the teeth and supporting structures
 Digestive 0.986 0.884 – 1.1 0.799 394 2767 exclusion phecode
525.1 Loss of teeth or edentulism Digestive 0.977 0.799 – 1.19 0.822 112 970 exclusion phecode
526 Diseases of the jaws Digestive 0.922 0.859 – 0.99 0.0246 906 6883 exclusion phecode
526.1 Cysts of the jaws Digestive 0.665 0.483 – 0.917 0.0127 42 619 exclusion phecode
526.3 Anomalies of jaw size/symmetry Digestive 0.879 0.633 – 1.22 0.439 40 473 exclusion phecode
526.4 Temporomandibular joint disorders Digestive 0.959 0.876 – 1.05 0.366 565 3859 exclusion phecode
526.41 Temporomandibular joint disorder, unspecified Digestive 0.929 0.837 – 1.03 0.164 431 3011 exclusion phecode
526.42 Arthralgia/ankylosis of temporomandibular joint Digestive 0.997 0.869 – 1.14 0.961 235 1867 exclusion phecode
526.5 Inflammatory conditions of jaw Digestive 0.883 0.663 – 1.18 0.393 53 758 exclusion phecode
526.8 Exostosis of jaw Digestive 0.754 0.4 – 1.42 0.382 11 140 exclusion phecode
526.9 Jaw disease NOS Digestive 0.805 0.666 – 0.974 0.0257 119 1330 exclusion phecode
527 Diseases of the salivary glands Digestive 0.981 0.903 – 1.07 0.645 671 4978 exclusion phecode
527.1 Hypertrophy of salivary gland Digestive 0.847 0.544 – 1.32 0.463 23 176 exclusion phecode
527.2 Sialoadenitis Digestive 1.01 0.849 – 1.19 0.95 169 1105 exclusion phecode
527.7 Disturbance of salivary secretion Digestive 1.02 0.914 – 1.14 0.7 367 2701 exclusion phecode
527.8 Other specified diseases of the salivary glands Digestive 0.953 0.754 – 1.2 0.684 78 711 exclusion phecode
528
Diseases of the oral soft tissues, excluding
Diseases of the oral soft tissues, excluding lesions specific for gingiva and tongue
 Digestive 0.957 0.895 – 1.02 0.2 1017 7219 exclusion phecode
528.1 Stomatitis and mucositis Digestive 0.799 0.704 – 0.907 0.000537 288 1830 exclusion phecode
528.11 Stomatitis and mucositis (ulcerative) Digestive 0.822 0.659 – 1.03 0.084 86 562 exclusion phecode
528.12 Oral aphthae Digestive 0.789 0.645 – 0.966 0.022 123 669 exclusion phecode
528.3 Cellulitis and abscess of oral soft tissues Digestive 0.895 0.698 – 1.15 0.384 73 607 exclusion phecode
528.4 Cysts of oral soft tissues Digestive 1.41 1 – 2 0.0482 37 322 exclusion phecode
528.41 Cyst of the salivary gland Digestive 1.03 0.681 – 1.55 0.901 24 198 exclusion phecode
528.5 Diseases of lips Digestive 0.962 0.833 – 1.11 0.596 225 1318 exclusion phecode
528.6 Leukoplakia of oral mucosa Digestive 1 0.718 – 1.4 0.991 36 372 exclusion phecode
528.7 Sialolithiasis Digestive 1.13 0.856 – 1.48 0.396 60 432 exclusion phecode
529 Diseases and other conditions of the tongue Digestive 1.04 0.91 – 1.18 0.583 270 1945 exclusion phecode
529.1 Glossitis Digestive 0.937 0.709 – 1.24 0.645 60 362 exclusion phecode
529.6 Glossodynia Digestive 0.999 0.754 – 1.32 0.995 62 496 exclusion phecode
530 Diseases of esophagus Digestive 0.987 0.951 – 1.02 0.469 6482 6484 exclusion phecode
530.1 Esophagitis, GERD and related diseases Digestive 0.988 0.952 – 1.02 0.502 6344 6484 exclusion phecode
530.11 GERD Digestive 0.985 0.949 – 1.02 0.415 6184 6483 exclusion phecode
530.12 Ulcer of esophagus Digestive 0.944 0.808 – 1.1 0.468 208 947 exclusion phecode
530.13 Barrett's esophagus Digestive 0.953 0.841 – 1.08 0.445 303 1838 exclusion phecode
530.14 Reflux esophagitis Digestive 0.962 0.897 – 1.03 0.271 1060 4264 exclusion phecode
530.15 Eosinophilic esophagitis Digestive 0.829 0.659 – 1.04 0.109 101 550 exclusion phecode
530.2 Esophageal bleeding (varices/hemorrhage) Digestive 0.953 0.84 – 1.08 0.455 305 1570 exclusion phecode
530.3 Stricture and stenosis of esophagus Digestive 0.971 0.865 – 1.09 0.621 355 2084 exclusion phecode
530.5 Disorders of esophageal motility Digestive 1.04 0.898 – 1.2 0.596 219 1305 exclusion phecode
530.6 Diverticulum of esophagus, acquired Digestive 1.22 0.791 – 1.87 0.372 25 295 exclusion phecode
530.7 Gastroesophageal laceration-hemorrhage syndrome Digestive 0.757 0.551 – 1.04 0.0867 48 230 exclusion phecode
530.9 Heartburn Digestive 0.967 0.893 – 1.05 0.41 780 3604 exclusion phecode
531 Peptic ulcer (excl. esophageal) Digestive 1 0.934 – 1.07 0.991 983 5933 exclusion phecode
531.1 Hemorrhage from gastrointestinal ulcer Digestive 0.968 0.835 – 1.12 0.666 205 1117 exclusion phecode
531.2 Gastric ulcer Digestive 0.984 0.899 – 1.08 0.727 569 3445 exclusion phecode
531.3 Duodenal ulcer Digestive 1.05 0.913 – 1.21 0.488 234 1366 exclusion phecode
531.4 Peptic ulcer, site unspecified Digestive 0.929 0.835 – 1.03 0.174 420 2388 exclusion phecode
531.5 Gastrojejunal ulcer Digestive 1.01 0.79 – 1.28 0.954 70 388 exclusion phecode
532 Dysphagia Digestive 0.986 0.937 – 1.04 0.581 2210 6139 exclusion phecode
535 Gastritis and duodenitis Digestive 1.01 0.949 – 1.07 0.835 1435 7165 exclusion phecode
535.1 Acute gastritis Digestive 1 0.915 – 1.1 0.921 554 3176 exclusion phecode
535.2 Atrophic gastritis Digestive 0.9 0.756 – 1.07 0.233 168 870 exclusion phecode
535.6 Duodenitis Digestive 0.922 0.784 – 1.08 0.329 182 944 exclusion phecode
535.8 Other specified gastritis Digestive 0.902 0.802 – 1.02 0.0875 349 1766 exclusion phecode
535.9 Gastritis and duodenitis, NOS Digestive 0.944 0.869 – 1.03 0.17 704 3368 exclusion phecode
536 Disorders of function of stomach Digestive 1.01 0.957 – 1.07 0.658 1511 7217 exclusion phecode
536.3 Gastroparesis Digestive 1.17 1.05 – 1.31 0.00628 381 2249 exclusion phecode
536.7
Complications of gastrostomy, colostomy and
Complications of gastrostomy, colostomy and enterostomy
 Digestive 0.983 0.824 – 1.17 0.846 140 916 exclusion phecode
536.8
Dyspepsia and other specified disorders of
Dyspepsia and other specified disorders of function of stomach
 Digestive 0.977 0.915 – 1.04 0.487 1179 5672 exclusion phecode
537 Other disorders of stomach and duodenum Digestive 1.05 0.999 – 1.11 0.0544 1673 7894 exclusion phecode
537.1 Lesions of stomach and duodenum Digestive 0.925 0.747 – 1.15 0.474 103 510 exclusion phecode
539 Bariatric surgery Digestive 0.952 0.88 – 1.03 0.219 792 4127 exclusion phecode
540 Appendiceal conditions Digestive 0.969 0.84 – 1.12 0.666 252 1390 exclusion phecode
540.1 Appendicitis Digestive 0.995 0.854 – 1.16 0.951 216 1199 exclusion phecode
540.11 Acute appendicitis Digestive 1 0.848 – 1.18 0.998 185 1006 exclusion phecode
550 Abdominal hernia Digestive 0.981 0.94 – 1.02 0.37 3057 9775 exclusion phecode
550.1 Inguinal hernia Digestive 0.937 0.872 – 1.01 0.0803 933 4398 exclusion phecode
550.2 Diaphragmatic hernia Digestive 0.967 0.909 – 1.03 0.28 1229 6736 exclusion phecode
550.3 Femoral hernia Digestive 0.89 0.694 – 1.14 0.355 72 350 exclusion phecode
550.4 Umbilical hernia Digestive 0.98 0.898 – 1.07 0.655 654 3432 exclusion phecode
550.5 Ventral hernia Digestive 0.988 0.921 – 1.06 0.727 974 5616 exclusion phecode
550.6 Incisional hernia Digestive 1.04 0.95 – 1.14 0.38 545 3358 exclusion phecode
555
Inflammatory bowel disease and other
Inflammatory bowel disease and other gastroenteritis and colitis
 Digestive 1.02 0.931 – 1.13 0.621 525 3013 exclusion phecode
555.1 Regional enteritis Digestive 0.993 0.875 – 1.13 0.908 312 1717 exclusion phecode
555.2 Ulcerative colitis Digestive 1.05 0.931 – 1.19 0.417 332 1855 exclusion phecode
555.21 Ulcerative colitis (chronic) Digestive 1.06 0.911 – 1.24 0.441 215 1039 exclusion phecode
556 Ulceration of the lower GI tract Digestive 0.913 0.805 – 1.04 0.156 351 1354 exclusion phecode
556.1 Ulceration of intestine Digestive 0.915 0.8 – 1.05 0.197 305 1169 exclusion phecode
556.11
Angiodysplasia of intestine (without mention of
Angiodysplasia of intestine (without mention of hemorrhage)
 Digestive 0.88 0.726 – 1.07 0.191 140 509 exclusion phecode
557 Intestinal malabsorption (non-celiac) Digestive 0.932 0.866 – 1 0.062 969 3460 exclusion phecode
557.1 Celiac disease Digestive 0.931 0.791 – 1.09 0.385 198 952 exclusion phecode
558 Noninfectious gastroenteritis Digestive 1.01 0.952 – 1.07 0.769 1623 5333 exclusion phecode
559 Ileostomy status Digestive 1.06 0.925 – 1.2 0.424 283 1665 exclusion phecode
560 Intestinal obstruction without mention of hernia Digestive 0.983 0.92 – 1.05 0.606 1202 4800 exclusion phecode
560.1 Paralytic ileus Digestive 1.01 0.928 – 1.11 0.746 608 2950 exclusion phecode
560.2 Impaction of intestine Digestive 0.867 0.739 – 1.02 0.0827 198 811 exclusion phecode
560.3 Peritoneal or intestinal adhesions Digestive 0.951 0.775 – 1.17 0.633 125 487 exclusion phecode
560.4 Other intestinal obstruction Digestive 0.941 0.865 – 1.02 0.159 699 3060 exclusion phecode
561 Symptoms involving digestive system Digestive 0.953 0.891 – 1.02 0.153 1202 4403 exclusion phecode
562 Diverticulosis and diverticulitis Digestive 0.95 0.905 – 0.997 0.0355 3372 4728 exclusion phecode
562.1 Diverticulosis Digestive 0.952 0.908 – 0.999 0.0467 3350 4711 exclusion phecode
562.2 Diverticulitis Digestive 0.895 0.823 – 0.973 0.00926 736 2991 exclusion phecode
564 Functional digestive disorders Digestive 1.01 0.969 – 1.05 0.671 4815 5799 exclusion phecode
564.1 Irritable Bowel Syndrome Digestive 0.972 0.913 – 1.03 0.371 1365 4567 exclusion phecode
564.9 Personal history of diseases of digestive system Digestive 1 0.941 – 1.06 0.981 1389 5048 exclusion phecode
565 Anal and rectal conditions Digestive 0.999 0.947 – 1.05 0.979 1716 7338 exclusion phecode
565.1 Anal and rectal polyp Digestive 0.993 0.917 – 1.08 0.869 754 3307 exclusion phecode
567 Peritonitis and retroperitoneal infections Digestive 0.969 0.884 – 1.06 0.503 575 2899 exclusion phecode
568 Other disorders of peritoneum Digestive 1.01 0.925 – 1.11 0.805 583 3733 exclusion phecode
568.1
Peritoneal adhesions (postoperative)
Peritoneal adhesions (postoperative) (postinfection)
 Digestive 0.974 0.872 – 1.09 0.633 379 2691 exclusion phecode
569 Other disorders of intestine Digestive 1 0.964 – 1.04 0.878 3812 8299 exclusion phecode
569.1 Toxic gastroenteritis and colitis Digestive 1.08 0.896 – 1.29 0.43 145 755 exclusion phecode
569.2 Gastrointestinal complications Digestive 0.984 0.9 – 1.08 0.719 596 3190 exclusion phecode
571 Chronic liver disease and cirrhosis Digestive 1.01 0.963 – 1.06 0.633 2130 7535 exclusion phecode
571.5 Other chronic nonalcoholic liver disease Digestive 1.01 0.961 – 1.06 0.682 2003 7476 exclusion phecode
571.51 Cirrhosis of liver without mention of alcohol Digestive 1.03 0.939 – 1.14 0.49 500 2518 exclusion phecode
571.6 Primary biliary cirrhosis Digestive 0.894 0.711 – 1.12 0.338 90 442 exclusion phecode
571.8
Liver abscess and sequelae of chronic liver
Liver abscess and sequelae of chronic liver disease
 Digestive 1.03 0.928 – 1.14 0.604 467 2326 exclusion phecode
571.81 Portal hypertension Digestive 0.938 0.824 – 1.07 0.326 293 1401 exclusion phecode
572 Ascites (non malignant) Digestive 0.996 0.928 – 1.07 0.907 948 5094 exclusion phecode
573 Other disorders of liver Digestive 0.994 0.949 – 1.04 0.787 2506 7831 exclusion phecode
573.1 Chronic passive congestion of liver Digestive 0.916 0.72 – 1.17 0.478 109 324 exclusion phecode
573.2 Liver replaced by transplant Digestive 1.1 0.922 – 1.3 0.299 192 696 exclusion phecode
573.3 Hepatomegaly Digestive 1.03 0.877 – 1.21 0.714 180 1202 exclusion phecode
573.4 Acute and subacute necrosis of liver Digestive 1.09 0.917 – 1.29 0.341 185 758 exclusion phecode
573.5 Jaundice (not of newborn) Digestive 0.984 0.888 – 1.09 0.761 469 2343 exclusion phecode
573.6
Nonspecific elevation of levels of transaminase
Nonspecific elevation of levels of transaminase or lactic acid dehydrogenase [LDH]
 Digestive 1.03 0.97 – 1.09 0.368 1568 6378 exclusion phecode
573.7 Abnormal results of function study of liver Digestive 1.01 0.954 – 1.06 0.794 1747 6648 exclusion phecode
573.9 Abnormal serum enzyme levels Digestive 1.03 0.982 – 1.08 0.239 2632 7899 exclusion phecode
574 Cholelithiasis and cholecystitis Digestive 0.981 0.929 – 1.04 0.495 1555 8382 exclusion phecode
574.1 Cholelithiasis Digestive 0.972 0.918 – 1.03 0.325 1440 7858 exclusion phecode
574.11 Cholelithiasis with acute cholecystitis Digestive 0.926 0.792 – 1.08 0.334 203 977 exclusion phecode
574.12 Cholelithiasis with other cholecystitis Digestive 0.956 0.836 – 1.09 0.513 263 1509 exclusion phecode
574.2 Calculus of bile duct Digestive 0.967 0.872 – 1.07 0.52 450 2311 exclusion phecode
574.3 Cholecystitis without cholelithiasis Digestive 0.959 0.866 – 1.06 0.417 453 2326 exclusion phecode
575 Other biliary tract disease Digestive 0.985 0.921 – 1.05 0.66 1053 6096 exclusion phecode
575.1 Cholangitis Digestive 0.985 0.834 – 1.16 0.862 163 951 exclusion phecode
575.2 Obstruction of bile duct Digestive 0.964 0.838 – 1.11 0.61 236 1616 exclusion phecode
575.6 Cholesterolosis of gallbladder Digestive 1.08 0.854 – 1.37 0.52 94 546 exclusion phecode
575.7 Other disorders of gallbladder Digestive 0.976 0.886 – 1.07 0.616 500 2575 exclusion phecode
575.8 Other disorders of biliary tract Digestive 0.95 0.864 – 1.05 0.297 497 3066 exclusion phecode
575.9
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of biliary tract
 Digestive 0.986 0.811 – 1.2 0.885 122 715 exclusion phecode
577 Diseases of pancreas Digestive 0.953 0.89 – 1.02 0.174 977 6616 exclusion phecode
577.1 Acute pancreatitis Digestive 0.901 0.823 – 0.987 0.0245 552 3676 exclusion phecode
577.2 Chronic pancreatitis Digestive 0.83 0.72 – 0.955 0.00947 242 1472 exclusion phecode
577.3 Cyst and pseudocyst of pancreas Digestive 1.01 0.88 – 1.16 0.887 261 1732 exclusion phecode
578 Gastrointestinal hemorrhage Digestive 1 0.957 – 1.05 0.943 2535 8939 exclusion phecode
578.1 Hematemesis Digestive 1.02 0.89 – 1.16 0.812 274 1279 exclusion phecode
578.2 Blood in stool Digestive 0.977 0.923 – 1.03 0.413 1582 6592 exclusion phecode
578.8 Hemorrhage of rectum and anus Digestive 1.02 0.962 – 1.09 0.451 1266 5424 exclusion phecode
578.9 Hemorrhage of gastrointestinal tract Digestive 1.01 0.934 – 1.08 0.864 882 3882 exclusion phecode
579 Other symptoms involving abdomen and pelvis Digestive 1.01 0.96 – 1.06 0.7 2026 8141 exclusion phecode
579.2 Splenomegaly Digestive 1.04 0.93 – 1.16 0.503 417 1889 exclusion phecode
579.8 Nonspecific abnormal findings in stool contents Digestive 0.96 0.888 – 1.04 0.297 829 3587 exclusion phecode
580 Nephritis; nephrosis; renal sclerosis Genitourinary 1.03 0.965 – 1.1 0.386 1299 3834 exclusion phecode
580.1 Glomerulonephritis Genitourinary 1.11 0.97 – 1.27 0.128 287 1030 exclusion phecode
580.11 Proliferative glomerulonephritis Genitourinary 1.14 0.903 – 1.44 0.271 99 372 exclusion phecode
580.12 Non-proliferative glomerulonephritis Genitourinary 1.13 0.867 – 1.48 0.363 77 286 exclusion phecode
580.13 Acute glomerulonephritis, NOS Genitourinary 1.01 0.702 – 1.44 0.977 43 148 exclusion phecode
580.14 Chronic glomerulonephritis, NOS Genitourinary 1.08 0.917 – 1.27 0.359 209 713 exclusion phecode
580.2
Nephrotic syndrome without mention of
Nephrotic syndrome without mention of glomerulonephritis
 Genitourinary 1.08 0.892 – 1.31 0.425 143 589 exclusion phecode
580.3
Nephritis and nephropathy without mention of
Nephritis and nephropathy without mention of glomerulonephritis
 Genitourinary 1.03 0.961 – 1.1 0.411 1120 3089 exclusion phecode
580.31
Nephritis and nephropathy in diseases
Nephritis and nephropathy in diseases classified elsewhere
 Genitourinary 1 0.922 – 1.09 0.989 833 2176 exclusion phecode
580.32
Nephritis and nephropathy with pathological
Nephritis and nephropathy with pathological lesion
 Genitourinary 1.08 0.969 – 1.2 0.168 434 1771 exclusion phecode
580.4 Renal sclerosis, NOS Genitourinary 0.997 0.847 – 1.17 0.975 187 832 exclusion phecode
585 Renal failure Genitourinary 1.02 0.982 – 1.07 0.262 3707 7465 exclusion phecode
585.1 Acute renal failure Genitourinary 1.03 0.985 – 1.09 0.179 2417 6262 exclusion phecode
585.2 Renal failure NOS Genitourinary 0.985 0.894 – 1.09 0.762 556 2009 exclusion phecode
585.3 Chronic renal failure [CKD] Genitourinary 1.03 0.98 – 1.08 0.258 2858 6876 exclusion phecode
585.31 Renal dialysis Genitourinary 1 0.909 – 1.11 0.93 516 1841 exclusion phecode
585.32 End stage renal disease Genitourinary 1.02 0.939 – 1.11 0.611 718 2407 exclusion phecode
585.33 Chronic Kidney Disease, Stage III Genitourinary 1.05 0.99 – 1.11 0.111 1889 5020 exclusion phecode
585.34 Chronic Kidney Disease, Stage IV Genitourinary 1.02 0.937 – 1.12 0.598 655 2277 exclusion phecode
585.4 Chronic kidney disease, Stage I or II Genitourinary 1.02 0.942 – 1.11 0.613 820 2839 exclusion phecode
586 Other disorders of the kidney and ureters Genitourinary 1.02 0.979 – 1.07 0.332 3504 7803 exclusion phecode
586.1 Anatomical abnormatilies of kidney and ureters Genitourinary 1.02 0.855 – 1.21 0.852 156 791 exclusion phecode
586.11 Small kidney Genitourinary 1.03 0.824 – 1.3 0.771 93 527 exclusion phecode
586.12 Vesicoureteral reflux Genitourinary 0.897 0.686 – 1.17 0.426 62 287 exclusion phecode
586.2 Cyst of kidney, acquired Genitourinary 1 0.92 – 1.09 0.947 670 2983 exclusion phecode
586.3 Vascular disorders of kidney/hypertrophy Genitourinary 1.11 0.913 – 1.36 0.286 124 463 exclusion phecode
586.4 Stricture/obstruction of ureter Genitourinary 0.994 0.913 – 1.08 0.895 640 3815 exclusion phecode
587 Kidney replaced by transpant Genitourinary 1.01 0.916 – 1.1 0.902 609 2022 exclusion phecode
588 Disorders resulting from impaired renal function Genitourinary 1 0.92 – 1.09 0.962 743 2405 exclusion phecode
588.1 Renal osteodystrophy Genitourinary 1.11 0.957 – 1.28 0.172 249 683 exclusion phecode
588.2 Secondary hyperparathyroidism (of renal origin) Genitourinary 0.984 0.893 – 1.08 0.741 571 1950 exclusion phecode
589 Abnormal results of function study of kidney Genitourinary 1 0.916 – 1.09 0.982 650 2429 exclusion phecode
590 Pyelonephritis Genitourinary 0.998 0.919 – 1.08 0.965 748 3218 exclusion phecode
591 Urinary tract infection Genitourinary 1.01 0.974 – 1.05 0.517 4411 7513 exclusion phecode
592 Cystitis and urethritis Genitourinary 1.02 0.963 – 1.09 0.464 1484 5346 exclusion phecode
592.1 Cystitis Genitourinary 1.02 0.964 – 1.09 0.439 1419 5116 exclusion phecode
592.11 Acute cystitis Genitourinary 1.03 0.958 – 1.11 0.406 976 3601 exclusion phecode
592.12 Chronic cystitis Genitourinary 0.86 0.705 – 1.05 0.14 120 542 exclusion phecode
592.13 Chronic interstitial cystitis Genitourinary 0.915 0.756 – 1.11 0.36 127 873 exclusion phecode
592.2 Urethritis and urethral syndrome Genitourinary 1.06 0.842 – 1.33 0.634 98 512 exclusion phecode
593 Hematuria Genitourinary 1.03 0.983 – 1.08 0.214 2432 7412 exclusion phecode
593.1 Gross hematuria Genitourinary 0.944 0.872 – 1.02 0.151 767 3726 exclusion phecode
593.2 Microscopic hematuria Genitourinary 1 0.913 – 1.09 0.994 568 2430 exclusion phecode
594 Urinary calculus Genitourinary 0.981 0.938 – 1.03 0.415 2397 10431 exclusion phecode
594.1 Calculus of kidney Genitourinary 0.984 0.939 – 1.03 0.501 2273 10389 exclusion phecode
594.2 Calculus of lower urinary tract Genitourinary 0.933 0.789 – 1.1 0.415 152 1113 exclusion phecode
594.3 Calculus of ureter Genitourinary 0.975 0.897 – 1.06 0.558 659 3861 exclusion phecode
594.8 Renal colic Genitourinary 0.939 0.787 – 1.12 0.48 164 978 exclusion phecode
595 Hydronephrosis Genitourinary 0.942 0.865 – 1.02 0.164 638 4457 exclusion phecode
596 Other disorders of bladder Genitourinary 0.974 0.915 – 1.04 0.402 1203 7744 exclusion phecode
596.1 Bladder neck obstruction Genitourinary 0.844 0.707 – 1.01 0.0604 149 1191 exclusion phecode
596.5 Functional disorders of bladder Genitourinary 0.97 0.896 – 1.05 0.457 737 4764 exclusion phecode
597 Other disorders of urethra and urinary tract Genitourinary 1.02 0.917 – 1.14 0.689 390 3291 exclusion phecode
597.1 Urethral stricture (not specified as infectious) Genitourinary 1.01 0.868 – 1.18 0.894 197 1822 exclusion phecode
597.2 Urinary complications NEC Genitourinary 0.998 0.892 – 1.12 0.971 353 2849 exclusion phecode
597.8 Urethral hypermobility/ISD Genitourinary 0.986 0.741 – 1.31 0.925 58 512 exclusion phecode
598 Abnormal findings on examination of urine Genitourinary 1.06 0.82 – 1.36 0.663 69 420 exclusion phecode
598.4 Other cells and casts in urine Genitourinary 1.06 0.809 – 1.4 0.658 59 377 exclusion phecode
599 Other symptoms/disorders or the urinary system Genitourinary 1.01 0.976 – 1.05 0.506 5846 7011 exclusion phecode
599.1 Urinary obstruction Genitourinary 0.903 0.804 – 1.01 0.084 351 1684 exclusion phecode
599.2 Retention of urine Genitourinary 0.988 0.937 – 1.04 0.657 1986 6231 exclusion phecode
599.3 Dysuria Genitourinary 1 0.955 – 1.06 0.875 2183 6340 exclusion phecode
599.4 Urinary incontinence Genitourinary 0.968 0.919 – 1.02 0.217 2155 6120 exclusion phecode
599.5 Frequency of urination and polyuria Genitourinary 1 0.954 – 1.05 0.988 2588 6666 exclusion phecode
599.6 Oliguria and anuria Genitourinary 0.946 0.839 – 1.07 0.367 341 1317 exclusion phecode
599.7 Urethral discharge Genitourinary 0.944 0.719 – 1.24 0.679 68 374 exclusion phecode
599.8 Other symptoms involving urinary system Genitourinary 1.02 0.973 – 1.08 0.362 2230 6406 exclusion phecode
599.9 Other abnormality of urination Genitourinary 0.956 0.901 – 1.01 0.133 1441 5761 exclusion phecode
600 Hyperplasia of prostate Genitourinary 0.949 0.892 – 1.01 0.0992 2055 3212 exclusion phecode
601 Inflammatory diseases of prostate Genitourinary 0.931 0.852 – 1.02 0.118 608 2793 exclusion phecode
601.1 Prostatitis Genitourinary 0.961 0.846 – 1.09 0.537 295 1382 exclusion phecode
601.11 Acute prostatitis Genitourinary 1.14 0.865 – 1.49 0.358 70 349 exclusion phecode
601.12 Chronic prostatitis Genitourinary 1.04 0.76 – 1.43 0.8 50 289 exclusion phecode
601.3 Orchitis and epididymitis Genitourinary 0.91 0.784 – 1.06 0.213 223 1107 exclusion phecode
601.4 Balanoposthitis Genitourinary 0.737 0.557 – 0.977 0.0335 66 327 exclusion phecode
601.8
Other inflammatory disorders of male genital
Other inflammatory disorders of male genital organs
 Genitourinary 1.02 0.813 – 1.28 0.868 94 449 exclusion phecode
602 Other disorders of prostate Genitourinary 0.957 0.809 – 1.13 0.606 171 973 exclusion phecode
602.3 Dysplasia of prostate Genitourinary 0.981 0.685 – 1.4 0.917 36 228 exclusion phecode
603 Other disorders of testis Genitourinary 0.88 0.757 – 1.02 0.0972 231 1055 exclusion phecode
603.1 Hydrocele Genitourinary 0.809 0.675 – 0.969 0.0217 164 721 exclusion phecode
603.2 Spermatocele Genitourinary 0.962 0.749 – 1.24 0.763 87 372 exclusion phecode
604 Disorders of penis Genitourinary 0.936 0.826 – 1.06 0.296 308 1566 exclusion phecode
604.1 Redundant prepuce and phimosis/BXO Genitourinary 1.25 0.968 – 1.62 0.0871 72 369 exclusion phecode
604.3 Peyronie's disease Genitourinary 0.754 0.584 – 0.972 0.0293 75 486 exclusion phecode
605 Erectile dysfunction [ED] Genitourinary 0.954 0.898 – 1.02 0.138 1895 2956 exclusion phecode
608 Other disorders of male genital organs Genitourinary 0.934 0.865 – 1.01 0.0797 893 3125 exclusion phecode
609 Male infertility and abnormal spermatozoa Genitourinary 0.829 0.71 – 0.968 0.0175 211 1133 exclusion phecode
609.1 Infertility, male Genitourinary 0.801 0.661 – 0.971 0.0236 139 795 exclusion phecode
609.11 Azoospermia and oligospermia Genitourinary 0.856 0.606 – 1.21 0.379 35 231 exclusion phecode
609.2 Abnormal spermatozoa Genitourinary 0.932 0.73 – 1.19 0.574 82 406 exclusion phecode
610 Benign mammary dysplasias Genitourinary 0.972 0.91 – 1.04 0.386 1472 3096 exclusion phecode
610.1 Cystic mastopathy Genitourinary 0.949 0.87 – 1.04 0.242 658 2604 exclusion phecode
610.2 Fibroadenosis of breast Genitourinary 0.947 0.611 – 1.47 0.806 31 113 exclusion phecode
610.4 Benign neoplasm of breast Genitourinary 0.992 0.923 – 1.07 0.822 1128 3054 exclusion phecode
610.8 Other specified benign mammary dysplasias Genitourinary 0.95 0.857 – 1.05 0.333 458 2186 exclusion phecode
611 Abnormal findings on mammogram or breast exam Genitourinary 0.982 0.931 – 1.03 0.488 2813 3902 exclusion phecode
611.1 Abnormal mammogram Genitourinary 0.979 0.925 – 1.04 0.473 2296 3098 exclusion phecode
611.11 Mammographic microcalcification Genitourinary 0.939 0.853 – 1.03 0.2 566 1929 exclusion phecode
611.3 Lump or mass in breast Genitourinary 0.978 0.921 – 1.04 0.478 1671 3867 exclusion phecode
612
Breast conditions, congenital or relating to
Breast conditions, congenital or relating to hormones
 Genitourinary 0.929 0.838 – 1.03 0.164 463 2222 exclusion phecode
612.1 Galactorrhea Genitourinary 1.18 0.888 – 1.55 0.258 73 310 exclusion phecode
612.2 Hypertrophy of breast (Gynecomastia) Genitourinary 0.905 0.805 – 1.02 0.0958 349 1697 exclusion phecode
612.3 Congenital anomalies of breast Genitourinary 0.632 0.403 – 0.99 0.0451 35 158 exclusion phecode
613 Other nonmalignant breast conditions Genitourinary 0.985 0.931 – 1.04 0.603 1713 5359 exclusion phecode
613.1 Inflammatory disease of breast Genitourinary 1.01 0.879 – 1.16 0.91 267 1419 exclusion phecode
613.5 Mastodynia Genitourinary 0.98 0.907 – 1.06 0.601 827 4029 exclusion phecode
613.7 Other signs and symptoms in breast Genitourinary 0.981 0.885 – 1.09 0.713 437 2199 exclusion phecode
613.8 Other specified disorders of breast Genitourinary 1.05 0.932 – 1.18 0.441 365 2131 exclusion phecode
613.9 Breast disorder NOS Genitourinary 0.971 0.886 – 1.06 0.536 570 3270 exclusion phecode
614 Inflammatory diseases of female pelvic organs Genitourinary 0.989 0.934 – 1.05 0.714 1735 4447 exclusion phecode
614.1
Pelvic peritoneal adhesions, female
Pelvic peritoneal adhesions, female (postoperative) (postinfection)
 Genitourinary 0.915 0.737 – 1.14 0.42 109 724 exclusion phecode
614.3 Pelvic inflammatory disease (PID) Genitourinary 1.11 0.949 – 1.3 0.19 197 1068 exclusion phecode
614.31 Acute inflammatory pelvic disease Genitourinary 1.03 0.69 – 1.53 0.891 31 203 exclusion phecode
614.32 Chronic inflammatory pelvic disease Genitourinary 1.11 0.853 – 1.46 0.426 69 372 exclusion phecode
614.33 Pelvic inflammatory disease, NOS Genitourinary 1.2 0.974 – 1.48 0.087 111 567 exclusion phecode
614.4 Inflammatory diseases of uterus, except cervix Genitourinary 1.16 0.906 – 1.48 0.24 80 387 exclusion phecode
614.5
Inflammatory disease of cervix, vagina, and
Inflammatory disease of cervix, vagina, and vulva
 Genitourinary 0.989 0.931 – 1.05 0.719 1560 4415 exclusion phecode
614.51 Cervicitis and endocervicitis Genitourinary 0.921 0.763 – 1.11 0.387 129 649 exclusion phecode
614.52 Vaginitis and vulvovaginitis Genitourinary 0.988 0.927 – 1.05 0.709 1362 4276 exclusion phecode
614.53 Cyst or abscess of Bartholin's gland Genitourinary 0.848 0.634 – 1.13 0.266 71 356 exclusion phecode
614.54 Abscess or ulceration of vulva Genitourinary 1.04 0.844 – 1.28 0.705 107 573 exclusion phecode
615 Endometriosis Genitourinary 0.939 0.855 – 1.03 0.192 545 3267 exclusion phecode
618 Genital prolapse Genitourinary 0.95 0.874 – 1.03 0.233 656 4596 exclusion phecode
618.1 Prolapse of vaginal walls Genitourinary 0.889 0.8 – 0.988 0.0293 398 3386 exclusion phecode
618.2 Uterine/Uterovaginal prolapse Genitourinary 0.928 0.791 – 1.09 0.362 170 1344 exclusion phecode
618.5 Prolapse of vaginal vault after hysterectomy Genitourinary 0.888 0.675 – 1.17 0.399 54 747 exclusion phecode
618.6 Vaginal enterocele, congenital or acquired Genitourinary 0.964 0.806 – 1.15 0.688 144 1096 exclusion phecode
619 Noninflammatory female genital disorders Genitourinary 0.997 0.946 – 1.05 0.911 2401 4099 exclusion phecode
619.1
Noninflammatory disorders of ovary, fallopian
Noninflammatory disorders of ovary, fallopian tube, and broad ligament
 Genitourinary 0.905 0.82 – 1 0.0506 500 2551 exclusion phecode
619.2 Disorders of uterus, NEC Genitourinary 0.99 0.869 – 1.13 0.886 283 1319 exclusion phecode
619.3 Noninflammatory disorders of cervix Genitourinary 0.961 0.826 – 1.12 0.609 217 1015 exclusion phecode
619.4 Noninflammatory disorders of vagina Genitourinary 0.994 0.928 – 1.06 0.859 1163 4007 exclusion phecode
619.5 Noninflammatory disorders of vulva and perineum Genitourinary 1.03 0.939 – 1.13 0.529 551 2729 exclusion phecode
620 Dysplasia of female genital organs Genitourinary 0.868 0.728 – 1.04 0.116 151 951 exclusion phecode
620.1 Dysplasia of cervix Genitourinary 0.911 0.71 – 1.17 0.459 79 426 exclusion phecode
621 Endometrial hyperplasia Genitourinary 0.818 0.697 – 0.962 0.0149 198 997 exclusion phecode
622 Polyp of female genital organs Genitourinary 0.905 0.833 – 0.983 0.0186 732 3513 exclusion phecode
622.1 Polyp of corpus uteri Genitourinary 0.907 0.826 – 0.996 0.0419 569 2718 exclusion phecode
622.2 Mucous polyp of cervix Genitourinary 0.825 0.714 – 0.954 0.00918 242 1094 exclusion phecode
623 Hypertrophy of female genital organs Genitourinary 0.989 0.888 – 1.1 0.847 394 2052 exclusion phecode
624 Symptoms involving female genital tract Genitourinary 0.999 0.914 – 1.09 0.989 650 2526 exclusion phecode
624.1 Dystrophy of female genital tract Genitourinary 0.946 0.762 – 1.18 0.619 94 485 exclusion phecode
624.2 Atrophy of female genital tract Genitourinary 0.983 0.659 – 1.47 0.933 25 159 exclusion phecode
624.9 stress incontinence, female Genitourinary 0.99 0.911 – 1.08 0.805 739 3080 exclusion phecode
625
Pain and other symptoms associated with female
Pain and other symptoms associated with female genital organs
 Genitourinary 0.952 0.903 – 1 0.0734 2507 3487 exclusion phecode
625.1 Dyspareunia Genitourinary 0.95 0.857 – 1.05 0.333 463 2404 exclusion phecode
626
Disorders of menstruation and other abnormal
Disorders of menstruation and other abnormal bleeding from female genital tract
 Genitourinary 0.957 0.903 – 1.01 0.132 2761 2669 exclusion phecode
626.1 Irregular menstrual cycle/bleeding Genitourinary 0.977 0.918 – 1.04 0.449 2232 2484 exclusion phecode
626.11 Absent or infrequent menstruation Genitourinary 0.973 0.879 – 1.08 0.59 559 1445 exclusion phecode
626.12 Excessive or frequent menstruation Genitourinary 0.954 0.884 – 1.03 0.225 1159 1983 exclusion phecode
626.13 Irregular menstrual cycle Genitourinary 0.989 0.915 – 1.07 0.776 1087 2078 exclusion phecode
626.14 Irregular menstrual bleeding Genitourinary 0.988 0.893 – 1.09 0.809 548 1482 exclusion phecode
626.15 Infertility, female, associated with anovulation Genitourinary 1.09 0.934 – 1.27 0.276 244 726 exclusion phecode
626.2 Dysmenorrhea Genitourinary 0.944 0.856 – 1.04 0.246 627 1610 exclusion phecode
626.4 Premenstrual tension syndromes Genitourinary 0.921 0.779 – 1.09 0.34 183 608 exclusion phecode
626.8 Infertility, female Genitourinary 1.07 0.956 – 1.21 0.229 439 1123 exclusion phecode
627 Menopausal and postmenopausal disorders Genitourinary 0.893 0.841 – 0.949 0.000237 1997 2485 exclusion phecode
627.1 Postmenopausal bleeding Genitourinary 0.858 0.775 – 0.949 0.00289 516 1789 exclusion phecode
627.2 Symptomatic menopause Genitourinary 0.881 0.822 – 0.944 0.00033 1349 2343 exclusion phecode
627.21 Symptomatic artificial menopause Genitourinary 0.891 0.686 – 1.16 0.39 72 266 exclusion phecode
627.22
Need for Hormone replacement therapy
Need for Hormone replacement therapy (postmenopausal)
 Genitourinary 0.902 0.762 – 1.07 0.232 160 706 exclusion phecode
627.3 Postmenopausal atrophic vaginitis Genitourinary 0.884 0.792 – 0.986 0.0271 412 1696 exclusion phecode
627.4 Premenopausal menorrhagia Genitourinary 0.994 0.844 – 1.17 0.943 197 635 exclusion phecode
627.5 Premature menopause and other ovarian failure Genitourinary 0.941 0.774 – 1.14 0.539 128 545 exclusion phecode
628 Ovarian cyst Genitourinary 0.937 0.865 – 1.02 0.114 903 2336 exclusion phecode
634 Miscarriage; stillbirth Pregnancy Complications 1.12 1 – 1.26 0.0408 407 2029 exclusion phecode
634.1 Missed abortion/Hydatidiform mole Pregnancy Complications 1.1 0.914 – 1.32 0.316 144 738 exclusion phecode
634.3 Ectopic pregnancy Pregnancy Complications 1.22 0.894 – 1.66 0.211 54 299 exclusion phecode
635
Hemorrhage during pregnancy; childbirth and
Hemorrhage during pregnancy; childbirth and postpartum
 Pregnancy Complications 1.22 1.07 – 1.39 0.00362 273 1348 exclusion phecode
635.2
Antepartum hemorrhage, abruptio placentae, and
Antepartum hemorrhage, abruptio placentae, and placenta previa
 Pregnancy Complications 1.18 0.997 – 1.4 0.0544 183 927 exclusion phecode
635.3 Placenta previa and abruptio placenta Pregnancy Complications 1.16 0.968 – 1.4 0.107 135 739 exclusion phecode
636
Early or threatened labor; hemorrhage in early
Early or threatened labor; hemorrhage in early pregnancy
 Pregnancy Complications 1.04 0.939 – 1.14 0.481 561 2014 exclusion phecode
636.1 Threatened premature labor Pregnancy Complications 0.992 0.844 – 1.17 0.926 196 922 exclusion phecode
636.2 Early onset of delivery Pregnancy Complications 0.938 0.788 – 1.12 0.478 158 730 exclusion phecode
636.3 Hemorrhage in early pregnancy Pregnancy Complications 1.13 0.973 – 1.31 0.11 238 1091 exclusion phecode
636.8 Cervical incompetence Pregnancy Complications 0.975 0.657 – 1.45 0.901 36 198 exclusion phecode
637
Short gestation; low birth weight; and fetal
Short gestation; low birth weight; and fetal growth retardation
 Pregnancy Complications 1.18 0.826 – 1.69 0.36 39 211 exclusion phecode
642
Hypertension complicating pregnancy
Hypertension complicating pregnancy, childbirth, and the puerperium
 Pregnancy Complications 1.15 1.01 – 1.31 0.0372 295 1640 exclusion phecode
642.1 Preeclampsia and eclampsia Pregnancy Complications 1.16 0.971 – 1.38 0.104 162 905 exclusion phecode
643 Excessive vomiting in pregnancy Pregnancy Complications 1.05 0.874 – 1.26 0.607 138 727 exclusion phecode
643.1 Hyperemesis gravidarum Pregnancy Complications 1.04 0.79 – 1.36 0.793 70 354 exclusion phecode
644 Anemia during pregnancy Pregnancy Complications 0.975 0.794 – 1.2 0.811 110 663 exclusion phecode
646 Other complications of pregnancy NEC Pregnancy Complications 1.09 0.975 – 1.23 0.126 386 1708 exclusion phecode
647
Infectious and parasitic complications
Infectious and parasitic complications affecting pregnancy
 Pregnancy Complications 1.01 0.821 – 1.25 0.914 109 663 exclusion phecode
647.1
Infections of genitourinary tract during
Infections of genitourinary tract during pregnancy
 Pregnancy Complications 0.998 0.794 – 1.25 0.987 95 620 exclusion phecode
647.3 Major puerperal infection Pregnancy Complications 1.12 0.76 – 1.65 0.569 29 196 exclusion phecode
649
Other conditions or status of the mother
Other conditions or status of the mother complicating pregnancy, childbirth, or the puerperium
 Pregnancy Complications 1.11 1.01 – 1.22 0.0332 622 2019 exclusion phecode
649.1
Diabetes or abnormal glucose tolerance
Diabetes or abnormal glucose tolerance complicating pregnancy
 Pregnancy Complications 1.11 0.992 – 1.24 0.0682 387 1734 exclusion phecode
653
Problems associated with amniotic cavity and
Problems associated with amniotic cavity and membranes
 Pregnancy Complications 1.07 0.942 – 1.22 0.289 286 1505 exclusion phecode
654.1
Abnormality of organs and soft tissues of
Abnormality of organs and soft tissues of pelvis complicating pregnancy, childbirth, or the puerperium
 Pregnancy Complications 1.12 0.899 – 1.39 0.321 107 546 exclusion phecode
654.2 Rhesus isoimmunization in pregnancy Pregnancy Complications 1.27 1.01 – 1.59 0.0409 107 558 exclusion phecode
655
Known or suspected fetal abnormality affecting
Known or suspected fetal abnormality affecting management of mother
 Pregnancy Complications 1.14 1.05 – 1.24 0.00152 815 2566 exclusion phecode
655.1 Abnormality in fetal heart rate or rhythm Pregnancy Complications 1.16 1.02 – 1.31 0.0253 320 1396 exclusion phecode
656 Other perinatal conditions of fetus or newborn Pregnancy Complications 1.08 0.966 – 1.2 0.182 422 1833 exclusion phecode
656.2 Respiratory conditions of fetus and newborn Pregnancy Complications 0.788 0.537 – 1.16 0.225 35 207 exclusion phecode
669 Complications of labor and delivery NEC Pregnancy Complications 1.08 0.967 – 1.2 0.171 426 1828 exclusion phecode
671
Venous/cerebrovascular complications embolism
Venous/cerebrovascular complications embolism in pregnancy and the puerperium
 Pregnancy Complications 0.968 0.762 – 1.23 0.792 97 579 exclusion phecode
674 Other complications of the puerperium NEC Pregnancy Complications 0.97 0.759 – 1.24 0.804 74 452 exclusion phecode
676
Other disorders of the breast associated with
Other disorders of the breast associated with childbirth and disorders of lactation
 Pregnancy Complications 1.03 0.829 – 1.28 0.801 108 554 exclusion phecode
681 Superficial cellulitis and abscess Dermatologic 0.983 0.944 – 1.02 0.402 3337 9273 exclusion phecode
681.1 Cellulitis and abscess of fingers/toes Dermatologic 0.961 0.891 – 1.04 0.31 846 3414 exclusion phecode
681.2 Cellulitis and abscess of face/neck Dermatologic 0.979 0.887 – 1.08 0.678 496 2590 exclusion phecode
681.3 Cellulitis and abscess of arm/hand Dermatologic 0.999 0.938 – 1.06 0.97 1276 5131 exclusion phecode
681.5 Cellulitis and abscess of leg, except foot Dermatologic 0.998 0.94 – 1.06 0.945 1367 5390 exclusion phecode
681.6 Cellulitis and abscess of foot, toe Dermatologic 1.04 0.973 – 1.11 0.246 1116 4478 exclusion phecode
681.7 Cellulitis and abscess of trunk Dermatologic 0.972 0.898 – 1.05 0.484 757 4016 exclusion phecode
686
Other local infections of skin and subcutaneous
Other local infections of skin and subcutaneous tissue
 Dermatologic 1 0.942 – 1.07 0.913 1194 5511 exclusion phecode
686.1 Carbuncle and furuncle Dermatologic 1.07 0.946 – 1.21 0.273 330 1527 exclusion phecode
686.2 Impetigo Dermatologic 0.954 0.828 – 1.1 0.512 244 1137 exclusion phecode
686.3 Pilonidal cyst Dermatologic 0.957 0.758 – 1.21 0.711 83 502 exclusion phecode
686.4 Pyogenic granuloma Dermatologic 0.953 0.737 – 1.23 0.71 74 407 exclusion phecode
686.5 Pyoderma Dermatologic 1.11 0.761 – 1.61 0.598 32 173 exclusion phecode
687 Symptoms affecting skin Dermatologic 0.98 0.912 – 1.05 0.585 940 3866 exclusion phecode
687.1 Rash and other nonspecific skin eruption Dermatologic 0.966 0.928 – 1.01 0.0965 3838 7505 exclusion phecode
687.3 Changes in skin texture Dermatologic 0.944 0.823 – 1.08 0.405 254 1208 exclusion phecode
687.4 Disturbance of skin sensation Dermatologic 0.966 0.925 – 1.01 0.117 3089 7440 exclusion phecode
689 Disorder of skin and subcutaneous tissue NOS Dermatologic 1.01 0.976 – 1.05 0.521 4833 8619 exclusion phecode
690 Erythematosquamous dermatosis Dermatologic 0.969 0.927 – 1.01 0.152 3005 7492 exclusion phecode
690.1 Seborrheic dermatitis Dermatologic 0.969 0.927 – 1.01 0.158 3000 7477 exclusion phecode
691 Congenital anomalies of skin Dermatologic 0.869 0.764 – 0.988 0.0319 296 1283 exclusion phecode
691.3 Congenital pigmentary anomalies of skin Dermatologic 0.775 0.466 – 1.29 0.326 21 133 exclusion phecode
694 Dyschromia and Vitiligo Dermatologic 0.969 0.903 – 1.04 0.373 978 4354 exclusion phecode
694.1 Vitiligo Dermatologic 0.895 0.703 – 1.14 0.366 71 403 exclusion phecode
694.2 Other dyschromia Dermatologic 0.955 0.886 – 1.03 0.223 873 3905 exclusion phecode
694.3 Vascular disorders of skin Dermatologic 1.39 0.985 – 1.96 0.0611 51 196 exclusion phecode
695 Erythematous conditions Dermatologic 0.933 0.887 – 0.98 0.0062 2111 7090 exclusion phecode
695.1 Toxic erythema Dermatologic 0.951 0.662 – 1.37 0.785 32 188 exclusion phecode
695.2 Bullous dermatoses Dermatologic 1.3 0.871 – 1.93 0.202 39 186 exclusion phecode
695.3 Rosacea Dermatologic 0.896 0.835 – 0.962 0.0025 980 4203 exclusion phecode
695.4 Lupus (localized and systemic) Dermatologic 0.99 0.868 – 1.13 0.881 277 1412 exclusion phecode
695.41 Cutaneous lupus erythematosus Dermatologic 1.03 0.843 – 1.25 0.786 119 509 exclusion phecode
695.42 Systemic lupus erythematosus Dermatologic 0.971 0.847 – 1.11 0.672 262 1344 exclusion phecode
695.7 Prurigo and Lichen Dermatologic 0.928 0.82 – 1.05 0.231 313 1445 exclusion phecode
695.8 Other specified erythematous conditions Dermatologic 0.915 0.827 – 1.01 0.0828 492 2002 exclusion phecode
695.81 Erythema nodosum Dermatologic 0.895 0.581 – 1.38 0.617 30 110 exclusion phecode
695.9 Unspecified erythematous condition Dermatologic 1.02 0.901 – 1.14 0.802 351 1701 exclusion phecode
696 Psoriasis and related disorders Dermatologic 0.948 0.869 – 1.03 0.225 632 3291 exclusion phecode
696.3 Pityriasis Dermatologic 1.01 0.739 – 1.39 0.934 51 197 exclusion phecode
696.4 Psoriasis Dermatologic 0.938 0.857 – 1.03 0.164 579 3120 exclusion phecode
696.41 Psoriasis vulgaris Dermatologic 0.934 0.851 – 1.02 0.15 552 2889 exclusion phecode
696.42 Psoriatic arthropathy Dermatologic 1.04 0.854 – 1.28 0.67 112 669 exclusion phecode
697 Sarcoidosis Dermatologic 1.03 0.859 – 1.24 0.745 137 797 exclusion phecode
698 Pruritus and related conditions Dermatologic 0.96 0.902 – 1.02 0.206 1218 6134 exclusion phecode
700 Corns and callosities Dermatologic 0.976 0.908 – 1.05 0.512 1010 3123 exclusion phecode
701
Other hypertrophic and atrophic conditions of
Other hypertrophic and atrophic conditions of skin
 Dermatologic 1 0.961 – 1.04 0.995 3724 9090 exclusion phecode
701.1 Keratoderma, acquired Dermatologic 0.994 0.879 – 1.12 0.926 342 1505 exclusion phecode
701.2 Scar conditions and fibrosis of skin Dermatologic 0.995 0.921 – 1.08 0.905 746 4924 exclusion phecode
701.3 Circumscribed scleroderma Dermatologic 1.04 0.897 – 1.2 0.629 229 1312 exclusion phecode
701.4 Keloid scar Dermatologic 0.995 0.865 – 1.14 0.946 245 1353 exclusion phecode
701.5 Abnormal granulation tissue Dermatologic 0.955 0.808 – 1.13 0.587 167 996 exclusion phecode
702
Degenerative skin conditions and other
Degenerative skin conditions and other dermatoses
 Dermatologic 0.993 0.952 – 1.04 0.752 3879 6404 exclusion phecode
702.1 Actinic keratosis Dermatologic 0.975 0.928 – 1.02 0.313 2399 6335 exclusion phecode
702.2 Seborrheic keratosis Dermatologic 0.984 0.942 – 1.03 0.46 3141 7743 exclusion phecode
702.4 Degenerative skin disorders Dermatologic 1.23 0.897 – 1.69 0.199 44 241 exclusion phecode
703 Diseases of nail, NOS Dermatologic 0.991 0.927 – 1.06 0.803 1092 4288 exclusion phecode
703.1 Ingrowing nail Dermatologic 0.952 0.872 – 1.04 0.281 634 2717 exclusion phecode
704 Diseases of hair and hair follicles Dermatologic 0.973 0.922 – 1.03 0.317 1713 7682 exclusion phecode
704.1 Alopecia Dermatologic 0.948 0.872 – 1.03 0.207 702 3436 exclusion phecode
704.11 Alopecia Areata Dermatologic 1.1 0.772 – 1.57 0.595 46 218 exclusion phecode
704.12 Telogen effluvium Dermatologic 0.893 0.602 – 1.33 0.574 39 119 exclusion phecode
704.2 Hirsutism Dermatologic 1.02 0.857 – 1.22 0.8 162 743 exclusion phecode
704.8
Other specified diseases of hair and hair
Other specified diseases of hair and hair follicles
 Dermatologic 1.01 0.941 – 1.08 0.822 1051 4986 exclusion phecode
705 Disorders of sweat glands Dermatologic 0.969 0.853 – 1.1 0.627 320 1538 exclusion phecode
705.1 Dyshidrosis Dermatologic 0.955 0.765 – 1.19 0.689 102 401 exclusion phecode
705.3 Hidradenitis Dermatologic 1.01 0.823 – 1.25 0.889 117 588 exclusion phecode
705.8 Hyperhidrosis Dermatologic 1.03 0.942 – 1.13 0.504 635 2879 exclusion phecode
706 Diseases of sebaceous glands Dermatologic 0.995 0.956 – 1.04 0.822 3452 9495 exclusion phecode
706.1 Acne Dermatologic 1 0.943 – 1.06 0.943 1435 5482 exclusion phecode
706.2 Sebaceous cyst Dermatologic 0.978 0.925 – 1.03 0.442 1619 6775 exclusion phecode
706.3 Seborrhea Dermatologic 1.22 0.816 – 1.82 0.335 41 162 exclusion phecode
706.8 Other specified diseases of sebaceous glands Dermatologic 0.975 0.912 – 1.04 0.47 1092 4201 exclusion phecode
707 Chronic ulcer of skin Dermatologic 1.04 0.982 – 1.1 0.187 1510 7540 exclusion phecode
707.1 Decubitus ulcer Dermatologic 1.16 1.04 – 1.28 0.00576 455 2403 exclusion phecode
707.2 Chronic ulcer of leg or foot Dermatologic 1.02 0.939 – 1.1 0.672 746 3279 exclusion phecode
707.3 Chronic ulcer of unspecified site Dermatologic 1 0.932 – 1.08 0.908 814 4675 exclusion phecode
709 Diffuse diseases of connective tissue Dermatologic 0.989 0.908 – 1.08 0.804 674 3317 exclusion phecode
709.2 Sicca syndrome Dermatologic 0.991 0.858 – 1.14 0.904 236 1047 exclusion phecode
709.3 Systemic sclerosis Dermatologic 0.911 0.725 – 1.15 0.428 94 466 exclusion phecode
709.5 Dermatomyositis Dermatologic 1.18 0.84 – 1.67 0.336 42 228 exclusion phecode
709.6
Other specified diffuse diseases of connective
Other specified diffuse diseases of connective tissue
 Dermatologic 0.815 0.576 – 1.15 0.249 40 173 exclusion phecode
709.7 Unspecified diffuse connective tissue disease Dermatologic 0.978 0.88 – 1.09 0.676 442 2180 exclusion phecode
710
Osteomyelitis, periostitis, and other
Osteomyelitis, periostitis, and other infections involving bone
 Musculoskeletal 1.02 0.935 – 1.12 0.622 571 3055 exclusion phecode
710.1 Osteomyelitis Musculoskeletal 1.02 0.935 – 1.12 0.606 554 2956 exclusion phecode
710.11 Acute osteomyelitis Musculoskeletal 1.04 0.921 – 1.17 0.527 320 1596 exclusion phecode
710.12 Chronic osteomyelitis Musculoskeletal 1.01 0.891 – 1.16 0.826 257 1440 exclusion phecode
710.19 Unspecified osteomyelitis Musculoskeletal 1.02 0.931 – 1.12 0.649 528 2845 exclusion phecode
711 Arthropathy associated with infections Musculoskeletal 0.955 0.816 – 1.12 0.567 200 971 exclusion phecode
711.1 Pyogenic arthritis Musculoskeletal 0.997 0.83 – 1.2 0.977 140 687 exclusion phecode
712 Infective connective tissue disorders Musculoskeletal 1.03 0.831 – 1.28 0.79 98 439 exclusion phecode
713
Arthropathy associated with other disorders
Arthropathy associated with other disorders classified elsewhere
 Musculoskeletal 0.945 0.808 – 1.11 0.482 207 1067 exclusion phecode
713.5
Arthropathy associated with neurological
Arthropathy associated with neurological disorders
 Musculoskeletal 0.934 0.783 – 1.11 0.447 154 775 exclusion phecode
714
Rheumatoid arthritis and other inflammatory
Rheumatoid arthritis and other inflammatory polyarthropathies
 Musculoskeletal 0.981 0.909 – 1.06 0.612 842 4432 exclusion phecode
714.1 Rheumatoid arthritis Musculoskeletal 0.973 0.892 – 1.06 0.546 633 3543 exclusion phecode
714.2 Juvenile rheumatoid arthritis Musculoskeletal 0.954 0.67 – 1.36 0.796 33 225 exclusion phecode
715 Other inflammatory spondylopathies Musculoskeletal 0.907 0.826 – 0.995 0.0383 567 2839 exclusion phecode
715.1 Sacroiliitis NEC Musculoskeletal 0.981 0.814 – 1.18 0.843 132 639 exclusion phecode
715.2 Ankylosing spondylitis Musculoskeletal 0.749 0.58 – 0.966 0.0261 68 495 exclusion phecode
716 Other arthropathies Musculoskeletal 0.964 0.927 – 1 0.0594 5113 7607 exclusion phecode
716.1 Unspecified polyarthropathy or polyarthritis Musculoskeletal 0.94 0.756 – 1.17 0.581 104 505 exclusion phecode
716.2 Unspecified monoarthritis Musculoskeletal 0.748 0.576 – 0.97 0.0287 62 292 exclusion phecode
716.9 Arthropathy NOS Musculoskeletal 0.963 0.927 – 1 0.0582 5073 7605 exclusion phecode
717 Polymyalgia Rheumatica Musculoskeletal 1.06 0.863 – 1.3 0.585 111 825 exclusion phecode
720 Spinal stenosis Musculoskeletal 0.962 0.909 – 1.02 0.172 1645 6868 exclusion phecode
720.1 Spinal stenosis of lumbar region Musculoskeletal 0.959 0.9 – 1.02 0.196 1248 5693 exclusion phecode
721 Spondylosis and allied disorders Musculoskeletal 0.971 0.927 – 1.02 0.21 2621 7998 exclusion phecode
721.1 Spondylosis without myelopathy Musculoskeletal 0.966 0.922 – 1.01 0.155 2499 7904 exclusion phecode
721.2 Spondylosis with myelopathy Musculoskeletal 0.934 0.83 – 1.05 0.259 333 2097 exclusion phecode
721.8 Other allied disorders of spine Musculoskeletal 0.84 0.694 – 1.02 0.0729 129 709 exclusion phecode
722 Intervertebral disc disorders Musculoskeletal 0.955 0.913 – 0.999 0.0466 2719 8336 exclusion phecode
722.1 Displacement of intervertebral disc Musculoskeletal 0.964 0.911 – 1.02 0.198 1579 7631 exclusion phecode
722.3 Schmorl's nodes Musculoskeletal 0.775 0.583 – 1.03 0.0786 68 280 exclusion phecode
722.6 Degeneration of intervertebral disc Musculoskeletal 0.953 0.904 – 1.01 0.076 1836 7557 exclusion phecode
722.7 Intervertebral disc disorder with myelopathy Musculoskeletal 0.996 0.848 – 1.17 0.957 189 1200 exclusion phecode
722.8 Postlaminectomy syndrome Musculoskeletal 1.14 0.963 – 1.35 0.127 161 976 exclusion phecode
722.9 Other and unspecified disc disorder Musculoskeletal 0.961 0.891 – 1.04 0.31 815 4818 exclusion phecode
723 Other disorders of cervical region Musculoskeletal 0.985 0.89 – 1.09 0.777 436 2307 exclusion phecode
723.1 Torticollis Musculoskeletal 1.02 0.836 – 1.23 0.88 120 631 exclusion phecode
724 Other and unspecified disorders of back Musculoskeletal 0.956 0.908 – 1.01 0.0848 1964 7833 exclusion phecode
724.1 Disorders of sacrum Musculoskeletal 0.97 0.909 – 1.03 0.349 1179 5411 exclusion phecode
724.2 Disorders of coccyx Musculoskeletal 0.887 0.766 – 1.03 0.106 247 1069 exclusion phecode
724.8 Other symptoms referable to back Musculoskeletal 0.895 0.807 – 0.992 0.0347 462 2297 exclusion phecode
724.9 Other unspecified back disorders Musculoskeletal 1.02 0.925 – 1.11 0.753 550 3295 exclusion phecode
726 Peripheral enthesopathies and allied syndromes Musculoskeletal 0.965 0.927 – 1 0.0722 5167 5680 exclusion phecode
726.1 Enthesopathy Musculoskeletal 0.965 0.924 – 1.01 0.0999 3822 5656 exclusion phecode
726.2 Synoviopathy Musculoskeletal 0.91 0.825 – 1 0.0575 538 1965 exclusion phecode
726.3 Bursitis Musculoskeletal 0.936 0.873 – 1 0.0603 1116 3320 exclusion phecode
726.4 Calcaneal spur; Exostosis NOS Musculoskeletal 0.921 0.841 – 1.01 0.0776 620 2264 exclusion phecode
727 Other disorders of synovium, tendon, and bursa Musculoskeletal 0.958 0.917 – 1 0.052 3733 5649 exclusion phecode
727.1 Synovitis and tenosynovitis Musculoskeletal 0.957 0.904 – 1.01 0.135 1670 4712 exclusion phecode
727.2 Bursitis disorders Musculoskeletal 0.978 0.837 – 1.14 0.776 226 833 exclusion phecode
727.4 Ganglion and cyst of synovium, tendon, and bursa Musculoskeletal 0.961 0.883 – 1.05 0.359 723 2663 exclusion phecode
727.5 Rupture of synovium Musculoskeletal 0.915 0.787 – 1.06 0.252 240 876 exclusion phecode
727.6 Rupture of tendon, nontraumatic Musculoskeletal 0.947 0.888 – 1.01 0.1 1274 4037 exclusion phecode
727.7 Contracture of tendon (sheath) Musculoskeletal 0.941 0.816 – 1.09 0.406 244 1133 exclusion phecode
727.8 Plica syndrome Musculoskeletal 0.907 0.646 – 1.27 0.572 49 225 exclusion phecode
728 Disorders of muscle, ligament, and fascia Musculoskeletal 0.969 0.92 – 1.02 0.228 2175 5489 exclusion phecode
728.1 Muscular calcification and ossification Musculoskeletal 0.899 0.611 – 1.32 0.589 34 188 exclusion phecode
728.2 Laxity of ligament or hypermobility syndrome Musculoskeletal 0.973 0.795 – 1.19 0.788 128 522 exclusion phecode
728.7 Fasciitis Musculoskeletal 0.964 0.911 – 1.02 0.199 1698 4506 exclusion phecode
728.71
Contracture of palmar fascia [Dupuytren's
Contracture of palmar fascia [Dupuytren's disease]
 Musculoskeletal 0.918 0.795 – 1.06 0.241 228 958 exclusion phecode
729 Other disorders of soft tissues Musculoskeletal 0.976 0.924 – 1.03 0.388 1886 5092 exclusion phecode
729.1 Rheumatism, unspecified and fibrositis Musculoskeletal 0.869 0.62 – 1.22 0.415 42 150 exclusion phecode
729.3 Panniculitis Musculoskeletal 1.2 0.878 – 1.65 0.25 62 236 exclusion phecode
729.7 Nontraumatic compartment syndrome Musculoskeletal 0.574 0.35 – 0.942 0.0282 23 133 exclusion phecode
731
Osteitis deformans and osteopathies associated
Osteitis deformans and osteopathies associated with other disorders classified elsewhere
 Musculoskeletal 0.958 0.791 – 1.16 0.659 148 706 exclusion phecode
732 Osteochondropathies Musculoskeletal 0.902 0.749 – 1.09 0.278 125 837 exclusion phecode
732.1 Juvenile osteochondrosis Musculoskeletal 0.894 0.71 – 1.12 0.338 83 506 exclusion phecode
732.7 Osteochondritis dissecans Musculoskeletal 0.792 0.55 – 1.14 0.21 33 194 exclusion phecode
733 Other disorders of bone and cartilage Musculoskeletal 0.981 0.931 – 1.03 0.47 2088 6583 exclusion phecode
733.2 Cyst of bone Musculoskeletal 1.2 0.923 – 1.56 0.174 72 428 exclusion phecode
733.4 Aseptic necrosis of bone Musculoskeletal 0.922 0.778 – 1.09 0.349 157 1200 exclusion phecode
733.6 Costochondritis Musculoskeletal 0.889 0.757 – 1.04 0.15 191 872 exclusion phecode
733.8 Malunion and nonunion of fracture Musculoskeletal 0.941 0.817 – 1.08 0.398 224 1832 exclusion phecode
733.9 Chondromalacia Musculoskeletal 1.14 0.774 – 1.68 0.509 29 196 exclusion phecode
735 Acquired foot deformities Musculoskeletal 1 0.951 – 1.05 0.957 1889 7938 exclusion phecode
735.1 Flat foot Musculoskeletal 1.05 0.935 – 1.18 0.409 362 1739 exclusion phecode
735.2 Acquired toe deformities Musculoskeletal 1.01 0.93 – 1.09 0.895 821 3626 exclusion phecode
735.21 Hammer toe (acquired) Musculoskeletal 0.964 0.877 – 1.06 0.458 535 2446 exclusion phecode
735.23 Hallux rigidus Musculoskeletal 1.09 0.934 – 1.26 0.286 220 1155 exclusion phecode
735.3 Hallux valgus (Bunion) Musculoskeletal 0.97 0.898 – 1.05 0.447 799 4038 exclusion phecode
736 Other acquired deformities of limbs Musculoskeletal 0.982 0.925 – 1.04 0.549 1362 7063 exclusion phecode
736.1 Acquired deformities of forearm Musculoskeletal 0.936 0.673 – 1.3 0.693 48 258 exclusion phecode
736.2 Acquired deformities of finger Musculoskeletal 1.09 0.889 – 1.34 0.398 110 576 exclusion phecode
736.3 Acquired deformities of hip Musculoskeletal 0.856 0.495 – 1.48 0.58 20 125 exclusion phecode
736.4 Genu valgum or varum (acquired) Musculoskeletal 0.85 0.71 – 1.02 0.0776 145 788 exclusion phecode
736.5 Acquired deformities of knee Musculoskeletal 0.893 0.729 – 1.09 0.276 110 629 exclusion phecode
736.6 Unequal leg length (acquired) Musculoskeletal 1.07 0.9 – 1.27 0.446 160 830 exclusion phecode
737 Curvature of spine Musculoskeletal 0.955 0.874 – 1.04 0.306 586 3694 exclusion phecode
737.1 Kyphosis (acquired) Musculoskeletal 0.944 0.807 – 1.1 0.471 170 1160 exclusion phecode
737.2 Lordosis (acquired) Musculoskeletal 1.1 0.702 – 1.72 0.678 19 168 exclusion phecode
737.3 Kyphoscoliosis and scoliosis Musculoskeletal 0.945 0.854 – 1.05 0.283 442 2784 exclusion phecode
738 Other acquired musculoskeletal deformity Musculoskeletal 0.97 0.9 – 1.05 0.423 815 5882 exclusion phecode
738.4 Acquired spondylolisthesis Musculoskeletal 0.944 0.848 – 1.05 0.292 407 2624 exclusion phecode
739 Contracture of joint Musculoskeletal 0.901 0.789 – 1.03 0.12 263 1585 exclusion phecode
740 Osteoarthrosis Musculoskeletal 0.967 0.931 – 1 0.0859 6187 7133 exclusion phecode
740.1 Osteoarthritis; localized Musculoskeletal 0.938 0.896 – 0.982 0.0059 3386 6421 exclusion phecode
740.11 Osteoarthrosis, localized, primary Musculoskeletal 0.93 0.887 – 0.975 0.00282 3021 6192 exclusion phecode
740.12 Osteoarthrosis, localized, secondary Musculoskeletal 0.886 0.781 – 1.01 0.061 300 1601 exclusion phecode
740.2 Osteoarthrosis, generalized Musculoskeletal 0.968 0.893 – 1.05 0.423 876 2691 exclusion phecode
740.3
Osteoarthrosis involving more than one site
Osteoarthrosis involving more than one site, but not specified as generalized
 Musculoskeletal 0.927 0.785 – 1.09 0.369 187 719 exclusion phecode
740.9 Osteoarthrosis NOS Musculoskeletal 0.969 0.932 – 1.01 0.106 5918 7097 exclusion phecode
741 Symptoms and disorders of the joints Musculoskeletal 0.991 0.952 – 1.03 0.639 3897 8644 exclusion phecode
741.1 Ankylosis of joint Musculoskeletal 0.854 0.664 – 1.1 0.22 72 535 exclusion phecode
741.2 Stiffness of joint Musculoskeletal 1.01 0.916 – 1.11 0.878 536 3072 exclusion phecode
741.3 Difficulty in walking Musculoskeletal 0.969 0.91 – 1.03 0.318 1258 5502 exclusion phecode
741.4 Joint effusions Musculoskeletal 1.04 0.979 – 1.11 0.2 1361 5803 exclusion phecode
741.5 Hemarthrosis Musculoskeletal 1.33 0.955 – 1.84 0.0916 58 255 exclusion phecode
741.6 Villonodular synovitis Musculoskeletal 0.843 0.54 – 1.32 0.451 30 150 exclusion phecode
742 Derangement of joint, non-traumatic Musculoskeletal 0.982 0.933 – 1.03 0.486 1948 8036 exclusion phecode
742.1 Loose body in joint Musculoskeletal 1.26 0.94 – 1.68 0.124 53 339 exclusion phecode
742.2
Pathological, developmental or recurrent
Pathological, developmental or recurrent dislocation
 Musculoskeletal 1.16 0.931 – 1.46 0.183 86 531 exclusion phecode
742.8 Articular cartilage disorder Musculoskeletal 1.02 0.811 – 1.27 0.886 90 562 exclusion phecode
742.9 Other derangement of joint Musculoskeletal 0.972 0.922 – 1.02 0.291 1837 7829 exclusion phecode
743
Osteoporosis, osteopenia and pathological
Osteoporosis, osteopenia and pathological fracture
 Musculoskeletal 0.991 0.951 – 1.03 0.652 3901 9323 exclusion phecode
743.1 Osteoporosis Musculoskeletal 1.01 0.946 – 1.07 0.813 1492 4878 exclusion phecode
743.11 Osteoporosis NOS Musculoskeletal 1.01 0.949 – 1.08 0.74 1462 4819 exclusion phecode
743.12 Senile osteoporosis Musculoskeletal 0.941 0.827 – 1.07 0.349 325 1110 exclusion phecode
743.13 Other specified osteoporosis Musculoskeletal 0.933 0.786 – 1.11 0.428 174 721 exclusion phecode
743.2 Pathologic fracture Musculoskeletal 0.961 0.87 – 1.06 0.434 478 2418 exclusion phecode
743.21 Pathologic fracture of vertebrae Musculoskeletal 0.952 0.82 – 1.11 0.521 206 1062 exclusion phecode
743.22 Pathologic fracture of femur Musculoskeletal 1.14 0.857 – 1.53 0.363 64 293 exclusion phecode
743.4 Stress fracture Musculoskeletal 1 0.866 – 1.16 0.981 227 1152 exclusion phecode
743.9
Osteopenia or other disorder of bone and
Osteopenia or other disorder of bone and cartilage
 Musculoskeletal 0.986 0.944 – 1.03 0.526 3208 8867 exclusion phecode
745 Pain in joint Musculoskeletal 0.961 0.926 – 0.997 0.0342 8758 4706 exclusion phecode
747 Cardiac and circulatory congenital anomalies Congenital Anomalies 1.03 0.969 – 1.1 0.314 1213 6189 exclusion phecode
747.1 Cardiac congenital anomalies Congenital Anomalies 1.03 0.964 – 1.11 0.354 1026 4929 exclusion phecode
747.11 Cardiac shunt/ heart septal defect Congenital Anomalies 0.942 0.836 – 1.06 0.326 375 1757 exclusion phecode
747.12 Valvular heart disease/ heart chambers Congenital Anomalies 1.11 1.01 – 1.23 0.0335 516 2149 exclusion phecode
747.13 Congenital anomalies of great vessels Congenital Anomalies 1.15 0.997 – 1.33 0.0554 233 1139 exclusion phecode
747.2
Congenital anomalies of peripheral vascular
Congenital anomalies of peripheral vascular system
 Congenital Anomalies 1.06 0.912 – 1.23 0.461 209 1360 exclusion phecode
748 Anomalies of respiratory system, congenital Congenital Anomalies 1.11 0.774 – 1.59 0.576 33 316 exclusion phecode
749 Congenital anomalies of face and neck Congenital Anomalies 0.946 0.8 – 1.12 0.513 161 1335 exclusion phecode
749.1 Cleft palate Congenital Anomalies 0.649 0.326 – 1.29 0.218 9 179 exclusion phecode
749.2 Congenital anomalies of skull and face bones Congenital Anomalies 1.18 0.802 – 1.74 0.4 29 237 exclusion phecode
750 Digestive congenital anomalies Congenital Anomalies 0.889 0.798 – 0.991 0.0339 382 2460 exclusion phecode
750.1 Upper gastrointestinal congenital anomalies Congenital Anomalies 0.922 0.761 – 1.12 0.403 108 968 exclusion phecode
750.11 Esophageal atresia/tracheoesophageal fistula Congenital Anomalies 0.815 0.598 – 1.11 0.197 45 319 exclusion phecode
750.13 Congenital anomalies of mouth/tongue Congenital Anomalies 0.896 0.602 – 1.33 0.586 26 216 exclusion phecode
750.14 Congenital anomalies of esophagus Congenital Anomalies 1.06 0.776 – 1.45 0.711 44 355 exclusion phecode
750.15 Congenital anomalies of stomach Congenital Anomalies 0.913 0.555 – 1.5 0.718 17 162 exclusion phecode
750.2 Lower gastrointestinal congenital anomalies Congenital Anomalies 0.911 0.8 – 1.04 0.157 273 1547 exclusion phecode
750.21 Congenital anomalies of intestine Congenital Anomalies 0.878 0.738 – 1.04 0.14 154 907 exclusion phecode
750.22
Congenital anomaly of gallbladder, bile ducts
Congenital anomaly of gallbladder, bile ducts, liver, pancreas
 Congenital Anomalies 0.84 0.687 – 1.03 0.0889 122 644 exclusion phecode
751 Genitourinary congenital anomalies Congenital Anomalies 0.964 0.896 – 1.04 0.332 875 5398 exclusion phecode
751.1 Congenital anomalies of genital organs Congenital Anomalies 1.01 0.882 – 1.16 0.862 241 1540 exclusion phecode
751.11 Congenital anomalies of female genital organs Congenital Anomalies 0.993 0.842 – 1.17 0.931 172 1012 exclusion phecode
751.12 Congenital anomalies of male genital organs Congenital Anomalies 1.05 0.773 – 1.41 0.773 50 423 exclusion phecode
751.2 Congenital anomalies of urinary system Congenital Anomalies 0.946 0.867 – 1.03 0.215 631 3757 exclusion phecode
751.21 Cystic kidney disease Congenital Anomalies 0.947 0.857 – 1.05 0.287 485 2721 exclusion phecode
751.22 Other specified congenital anomalies of kidney Congenital Anomalies 0.864 0.704 – 1.06 0.16 108 785 exclusion phecode
751.3 Obstructive genitourinary defect Congenital Anomalies 0.95 0.711 – 1.27 0.727 49 466 exclusion phecode
752 Nervous system congenital anomalies Congenital Anomalies 0.976 0.875 – 1.09 0.657 382 3022 exclusion phecode
752.1 Neural tube defects Congenital Anomalies 0.977 0.865 – 1.1 0.709 301 2442 exclusion phecode
752.11 Spina bifida Congenital Anomalies 1.27 0.943 – 1.72 0.115 46 434 exclusion phecode
752.2
Other specified congenital anomalies of nervous
Other specified congenital anomalies of nervous system
 Congenital Anomalies 0.991 0.781 – 1.26 0.941 83 590 exclusion phecode
753 Congenital anomalies of the eye Congenital Anomalies 1.06 0.863 – 1.31 0.564 112 710 exclusion phecode
753.1 Congenital cataract and lens anomalies Congenital Anomalies 1.13 0.781 – 1.64 0.513 36 191 exclusion phecode
753.2 Congenital anomalies of posterior segment of eye Congenital Anomalies 1.03 0.699 – 1.53 0.869 30 199 exclusion phecode
754 Congenital musculoskeletal deformities of spine Congenital Anomalies 0.962 0.87 – 1.06 0.454 453 3299 exclusion phecode
754.1 Lumbosacral spondylolysis, congenital Congenital Anomalies 1.06 0.795 – 1.42 0.684 68 389 exclusion phecode
754.2 Spondylolisthesis, congenital Congenital Anomalies 1 0.86 – 1.17 0.99 199 1505 exclusion phecode
755 Congenital anomalies of limbs Congenital Anomalies 0.982 0.868 – 1.11 0.776 305 2084 exclusion phecode
755.1 Congenital deformities of feet Congenital Anomalies 1.02 0.861 – 1.21 0.816 165 1058 exclusion phecode
755.4
Congenital anomalies of upper limb, including
Congenital anomalies of upper limb, including shoulder girdle
 Congenital Anomalies 1.26 0.793 – 2.02 0.324 27 200 exclusion phecode
755.6
Other congenital anomalies of lower limb
Other congenital anomalies of lower limb, including pelvic girdle
 Congenital Anomalies 0.901 0.738 – 1.1 0.309 114 813 exclusion phecode
755.61 Congenital hip dysplasia and deformity Congenital Anomalies 0.91 0.694 – 1.19 0.492 59 489 exclusion phecode
756 Other congenital musculoskeletal anomalies Congenital Anomalies 0.976 0.89 – 1.07 0.613 530 3608 exclusion phecode
756.1 Congenital anomalies of abdominal wall; diaphram Congenital Anomalies 0.97 0.616 – 1.53 0.895 24 175 exclusion phecode
756.2
Pectus and other congenital anomalies of
Pectus and other congenital anomalies of ribs/sternum
 Congenital Anomalies 1.2 0.749 – 1.91 0.453 25 140 exclusion phecode
756.3
Congenital anomalies of muscle, tendon, fascia
Congenital anomalies of muscle, tendon, fascia, and connective tissue
 Congenital Anomalies 0.942 0.792 – 1.12 0.499 142 836 exclusion phecode
756.5 Congenital osteodystrophies Congenital Anomalies 0.997 0.897 – 1.11 0.95 400 2758 exclusion phecode
757 Congenital anomalies of the integument Congenital Anomalies 1.18 0.999 – 1.39 0.0521 165 1135 exclusion phecode
758 Chromosomal anomalies and genetic disorders Congenital Anomalies 0.971 0.772 – 1.22 0.799 96 539 exclusion phecode
758.1 Chromosomal anomalies Congenital Anomalies 0.986 0.759 – 1.28 0.915 68 404 exclusion phecode
759 Other and unspecified congenital anomalies Congenital Anomalies 1.07 0.921 – 1.23 0.394 219 1444 exclusion phecode
759.1 Anomalies of endocrine glands, congenital Congenital Anomalies 1.08 0.72 – 1.63 0.699 26 193 exclusion phecode
760 Back pain Symptoms 1 0.968 – 1.04 0.9 7216 6250 exclusion phecode
761 Cervicalgia Symptoms 0.964 0.925 – 1 0.0768 3207 10151 exclusion phecode
763
Thoracic or lumbosacral neuritis or
Thoracic or lumbosacral neuritis or radiculitis, unspecified
 Symptoms 0.97 0.92 – 1.02 0.257 1759 8214 exclusion phecode
764 Sciatica Symptoms 1 0.95 – 1.06 0.966 1778 8223 exclusion phecode
765 Cervical radiculitis Symptoms 0.98 0.911 – 1.05 0.588 895 4690 exclusion phecode
766 Neuralgia, neuritis, and radiculitis NOS Symptoms 0.966 0.922 – 1.01 0.151 2344 9286 exclusion phecode
767 Cervicocranial/Cervicobrachial syndrome Symptoms 1.19 0.912 – 1.56 0.198 68 337 exclusion phecode
769 Nonallopathic lesions NEC Symptoms 0.973 0.889 – 1.07 0.554 603 3303 exclusion phecode
770 Myalgia and myositis unspecified Symptoms 0.984 0.94 – 1.03 0.487 2468 9223 exclusion phecode
771 Musculoskeletal symptoms referable to limbs Symptoms 0.954 0.909 – 1 0.0614 2175 8384 exclusion phecode
771.1 Swelling of limb Symptoms 0.971 0.929 – 1.01 0.175 3008 8469 exclusion phecode
771.2 Cramp of limb Symptoms 0.941 0.86 – 1.03 0.184 635 2789 exclusion phecode
772 Symptoms of the muscles Symptoms 0.963 0.899 – 1.03 0.288 1017 5338 exclusion phecode
772.1 Muscular wasting and disuse atrophy Symptoms 1.15 0.971 – 1.37 0.103 165 1032 exclusion phecode
772.2 Spasm of muscle Symptoms 0.962 0.899 – 1.03 0.252 1075 5883 exclusion phecode
772.3 Muscle weakness Symptoms 0.999 0.942 – 1.06 0.974 1455 7211 exclusion phecode
772.4 Rhabdomyolysis Symptoms 1.34 1.05 – 1.69 0.0169 86 443 exclusion phecode
772.6 Facial weakness Symptoms 0.963 0.842 – 1.1 0.579 267 1280 exclusion phecode
780 Hypothermia/Chills Symptoms 1.12 0.976 – 1.3 0.103 252 1407 exclusion phecode
781
Symptoms involving nervous and musculoskeletal
Symptoms involving nervous and musculoskeletal systems
 Symptoms 1.01 0.952 – 1.07 0.797 1466 7338 exclusion phecode
781.1 Loss of height Symptoms 0.901 0.7 – 1.16 0.414 73 397 exclusion phecode
781.2 Abnormal posture Symptoms 1.22 0.802 – 1.86 0.351 28 154 exclusion phecode
782.3 Edema Symptoms 1.06 1.01 – 1.1 0.0106 3163 9128 exclusion phecode
782.6 Pallor and flushing Symptoms 1.02 0.914 – 1.14 0.743 398 2296 exclusion phecode
783 Fever of unknown origin Symptoms 1.03 0.989 – 1.08 0.148 2851 10476 exclusion phecode
783.1 Postprocedural fever Symptoms 1.06 0.863 – 1.31 0.564 109 730 exclusion phecode
785 Abdominal pain Symptoms 0.958 0.924 – 0.992 0.0167 7446 6016 exclusion phecode
788 Syncope and collapse Symptoms 1.02 0.975 – 1.08 0.343 2079 9621 exclusion phecode
789 Nausea and vomiting Symptoms 1.02 0.98 – 1.06 0.367 4327 9083 exclusion phecode
789.1 Persistent vomiting Symptoms 0.925 0.825 – 1.04 0.176 357 1930 exclusion phecode
790 Nonspecific findings on examination of blood Symptoms 1.01 0.946 – 1.07 0.854 1365 5395 exclusion phecode
790.1 Elevated sedimentation rate Symptoms 1.18 0.965 – 1.44 0.108 124 594 exclusion phecode
790.6 Other abnormal blood chemistry Symptoms 1.01 0.969 – 1.05 0.723 4289 8652 exclusion phecode
790.8 Elevated C-reactive protein (CRP) Symptoms 1 0.845 – 1.19 0.958 151 719 exclusion phecode
790.9 Abnormal arterial blood gases Symptoms 1.13 0.889 – 1.44 0.313 80 347 exclusion phecode
791 Gangrene Symptoms 1.08 0.915 – 1.27 0.376 177 1036 exclusion phecode
792
Abnormal Papanicolaou smear of cervix and
Abnormal Papanicolaou smear of cervix and cervical HPV
 Genitourinary 1.02 0.952 – 1.09 0.577 1220 3201 exclusion phecode
792.1
Papanicolaou smear of cervix or vagina with
Papanicolaou smear of cervix or vagina with atypical squamous cells
 Genitourinary 1.05 0.95 – 1.17 0.329 497 2093 exclusion phecode
794
Abnormal results of other function studies
Abnormal results of other function studies (bladder, pancreas, placenta, spleen, etc)
 Symptoms 1.12 0.935 – 1.33 0.222 153 1418 exclusion phecode
795
Other and nonspecific abnormal cytological
Other and nonspecific abnormal cytological, histological and immunological findings
 Symptoms 1.01 0.942 – 1.09 0.712 867 5289 exclusion phecode
795.8 Abnormal tumor markers Symptoms 0.947 0.872 – 1.03 0.198 669 4766 exclusion phecode
795.81 Elevated carcinoembryonic antigen [CEA] Symptoms 0.875 0.563 – 1.36 0.552 19 172 exclusion phecode
795.82 Elevated cancer antigen 125 [CA 125] Symptoms 0.843 0.635 – 1.12 0.237 55 483 exclusion phecode
796 Elevated prostate specific antigen [PSA] Genitourinary 0.897 0.829 – 0.971 0.00703 921 2769 exclusion phecode
797 Shock Symptoms 1.03 0.92 – 1.16 0.591 368 1814 exclusion phecode
797.1 Cardiogenic shock Symptoms 1.05 0.89 – 1.25 0.539 190 773 exclusion phecode
798 Malaise and fatigue Symptoms 1 0.968 – 1.04 0.883 5882 7577 exclusion phecode
798.1 Chronic fatigue syndrome Symptoms 0.987 0.918 – 1.06 0.72 975 3969 exclusion phecode
800 Fracture of lower limb Injuries & Poisonings 0.974 0.909 – 1.04 0.465 968 5838 exclusion phecode
800.1 Fracture of neck of femur Injuries & Poisonings 1.05 0.91 – 1.21 0.507 225 1291 exclusion phecode
800.2 Fracture of unspecified part of femur Injuries & Poisonings 1.04 0.915 – 1.19 0.524 264 1626 exclusion phecode
800.3 Fracture of tibia and fibula Injuries & Poisonings 0.886 0.79 – 0.995 0.0405 367 2211 exclusion phecode
800.4 Fracture of patella Injuries & Poisonings 0.934 0.784 – 1.11 0.443 155 896 exclusion phecode
801 Fracture of ankle and foot Injuries & Poisonings 0.969 0.909 – 1.03 0.326 1220 6124 exclusion phecode
801.1 Fracture of foot Injuries & Poisonings 0.921 0.837 – 1.01 0.0905 500 2885 exclusion phecode
802 Fracture of pelvis Injuries & Poisonings 0.984 0.825 – 1.17 0.858 144 926 exclusion phecode
803 Fracture of upper limb Injuries & Poisonings 0.91 0.844 – 0.981 0.0134 842 5147 exclusion phecode
803.1 Fracture of humerus Injuries & Poisonings 0.911 0.801 – 1.04 0.159 301 1788 exclusion phecode
803.2 Fracture of radius and ulna Injuries & Poisonings 0.939 0.85 – 1.04 0.218 484 2844 exclusion phecode
803.21 Colles' fracture Injuries & Poisonings 0.892 0.735 – 1.08 0.248 126 716 exclusion phecode
803.3 Fracture of clavicle or scapula Injuries & Poisonings 0.84 0.714 – 0.988 0.0348 178 1287 exclusion phecode
804 Fracture of hand or wrist Injuries & Poisonings 0.975 0.9 – 1.06 0.528 761 4154 exclusion phecode
805
Fracture of vertebral column without mention of
Fracture of vertebral column without mention of spinal cord injury
 Injuries & Poisonings 0.982 0.895 – 1.08 0.694 560 3307 exclusion phecode
807 Fracture of ribs Injuries & Poisonings 0.936 0.835 – 1.05 0.261 352 1857 exclusion phecode
809 Fracture of unspecified bones Injuries & Poisonings 0.93 0.873 – 0.99 0.0238 1168 7332 exclusion phecode
816 Cerebral laceration and contusion Injuries & Poisonings 1.07 0.687 – 1.67 0.759 23 141 exclusion phecode
817 Concussion Injuries & Poisonings 1.01 0.916 – 1.11 0.852 520 2798 exclusion phecode
818 Intracranial hemorrhage (injury) Injuries & Poisonings 0.96 0.805 – 1.15 0.654 144 959 exclusion phecode
818.1 Subdural hemorrhage (injury) Injuries & Poisonings 0.834 0.602 – 1.16 0.276 43 270 exclusion phecode
818.2 Subarachnoid hemorrhage (injury) Injuries & Poisonings 1.49 1.05 – 2.12 0.027 42 321 exclusion phecode
819
Skull and face fracture and other intercranial
Skull and face fracture and other intercranial injury
 Injuries & Poisonings 1.02 0.948 – 1.09 0.615 938 6167 exclusion phecode
830 Dislocation Injuries & Poisonings 0.976 0.926 – 1.03 0.375 1710 9170 exclusion phecode
835 Internal derangement of knee Injuries & Poisonings 0.981 0.916 – 1.05 0.575 1059 5909 exclusion phecode
836 Traumatic arthropathy Injuries & Poisonings 0.915 0.784 – 1.07 0.259 212 1259 exclusion phecode
840 Sprains and strains Injuries & Poisonings 0.98 0.943 – 1.02 0.321 3794 9152 exclusion phecode
840.1 Muscle/tendon sprain Injuries & Poisonings 0.952 0.837 – 1.08 0.454 290 1344 exclusion phecode
840.2 Rotator cuff (capsule) sprain Injuries & Poisonings 0.918 0.851 – 0.991 0.0281 850 4161 exclusion phecode
840.3 Joint/ligament sprain Injuries & Poisonings 0.98 0.921 – 1.04 0.533 1266 6052 exclusion phecode
841 Sprains and strains of back and neck Injuries & Poisonings 0.939 0.873 – 1.01 0.093 939 4095 exclusion phecode
842 Other sprains and strains Injuries & Poisonings 0.936 0.862 – 1.02 0.122 744 3477 exclusion phecode
850 Hemorrhage or hematoma complicating a procedure Injuries & Poisonings 1.04 0.965 – 1.12 0.311 834 5247 exclusion phecode
851
Complications of transplants and reattached
Complications of transplants and reattached limbs
 Injuries & Poisonings 1.02 0.962 – 1.09 0.47 1318 6991 exclusion phecode
853 Complication of colostomy or enterostomy Injuries & Poisonings 1.09 0.921 – 1.29 0.314 163 1015 exclusion phecode
854
Complications of cardiac/vascular device
Complications of cardiac/vascular device, implant, and graft
 Injuries & Poisonings 1.07 1 – 1.15 0.0432 1103 5213 exclusion phecode
855
Complication of nervous system device, implant
Complication of nervous system device, implant, and graft
 Injuries & Poisonings 1.37 1.05 – 1.8 0.0216 64 635 exclusion phecode
856
Vascular complications of surgery and medical
Vascular complications of surgery and medical procedures
 Injuries & Poisonings 1.06 0.88 – 1.28 0.542 148 728 exclusion phecode
857
Mechanical complication of unspecified
Mechanical complication of unspecified genitourinary device, implant, and graft
 Injuries & Poisonings 0.987 0.895 – 1.09 0.801 484 3287 exclusion phecode
858 Complication of internal orthopedic device Injuries & Poisonings 0.997 0.915 – 1.09 0.953 600 5113 exclusion phecode
859
Complication due to other implant and internal
Complication due to other implant and internal device
 Injuries & Poisonings 1.03 0.948 – 1.11 0.505 682 5234 exclusion phecode
860 Bone marrow or stem cell transplant Neoplasms 0.964 0.76 – 1.22 0.761 83 522 exclusion phecode
870 Open wounds of head; neck; and trunk Injuries & Poisonings 0.992 0.941 – 1.05 0.777 1663 9392 exclusion phecode
870.1 Open wound or laceration of eye or eyelid Injuries & Poisonings 0.969 0.77 – 1.22 0.79 89 585 exclusion phecode
870.2 Open wound of ear Injuries & Poisonings 1.14 0.844 – 1.53 0.396 54 357 exclusion phecode
870.3 Other open wound of head and face Injuries & Poisonings 0.958 0.872 – 1.05 0.373 514 3462 exclusion phecode
870.4 Open wound of nose and sinus Injuries & Poisonings 1.02 0.78 – 1.33 0.889 63 503 exclusion phecode
870.5 Open wound of lip and mouth Injuries & Poisonings 0.959 0.759 – 1.21 0.729 81 681 exclusion phecode
870.6 Open wound of neck Injuries & Poisonings 0.95 0.692 – 1.3 0.749 45 518 exclusion phecode
870.8 Open wound of genital organs Injuries & Poisonings 0.962 0.703 – 1.32 0.807 42 386 exclusion phecode
871 Open wounds of extremities Injuries & Poisonings 0.978 0.929 – 1.03 0.398 1816 8743 exclusion phecode
871.1 Open wound of hand except finger(s) Injuries & Poisonings 0.982 0.863 – 1.12 0.787 293 1550 exclusion phecode
871.2 Open wound of finger(s) Injuries & Poisonings 0.944 0.86 – 1.04 0.22 555 2984 exclusion phecode
871.3 Open wound of foot except toe(s) alone Injuries & Poisonings 1.02 0.897 – 1.15 0.809 323 1626 exclusion phecode
871.4 Open wound of toe(s) Injuries & Poisonings 1.03 0.887 – 1.2 0.68 217 1083 exclusion phecode
872 Traumatic amputation Injuries & Poisonings 1.06 0.93 – 1.21 0.381 270 1617 exclusion phecode
874 Complication of amputation stump Injuries & Poisonings 1.15 0.921 – 1.43 0.221 102 517 exclusion phecode
875 Non-healing surgical wound Injuries & Poisonings 0.983 0.843 – 1.15 0.828 204 1431 exclusion phecode
876
Posttraumatic wound infection not elsewhere
Posttraumatic wound infection not elsewhere classified
 Injuries & Poisonings 1.08 0.964 – 1.2 0.193 373 2179 exclusion phecode
907 Injuries to the nervous system Injuries & Poisonings 1.02 0.912 – 1.15 0.693 331 2724 exclusion phecode
910 Superficial injury, infected Injuries & Poisonings 1.12 0.851 – 1.48 0.412 72 377 exclusion phecode
911 Blister Injuries & Poisonings 0.881 0.758 – 1.02 0.1 213 1193 exclusion phecode
912 Insect bite Injuries & Poisonings 0.838 0.741 – 0.947 0.00452 309 1590 exclusion phecode
913 Toxic effect of venom Injuries & Poisonings 0.826 0.711 – 0.96 0.0125 212 1065 exclusion phecode
916 Contusion Injuries & Poisonings 0.99 0.945 – 1.04 0.658 2394 9911 exclusion phecode
930 Allergic reaction to food Injuries & Poisonings 0.976 0.871 – 1.1 0.685 384 1548 exclusion phecode
931
Contact dermatitis and other eczema due to
Contact dermatitis and other eczema due to plants [except food]
 Dermatologic 0.843 0.751 – 0.947 0.00383 397 1611 exclusion phecode
938 Dermatitis due to solar radiation Dermatologic 0.987 0.943 – 1.03 0.563 3042 5862 exclusion phecode
938.1 Acute dermatitis due to solar radiation Dermatologic 1.1 0.886 – 1.37 0.387 119 435 exclusion phecode
938.2 Chronic dermatitis due to solar radiation Dermatologic 0.985 0.941 – 1.03 0.528 2946 5785 exclusion phecode
939
Atopic/contact dermatitis due to other or
Atopic/contact dermatitis due to other or unspecified
 Dermatologic 0.971 0.932 – 1.01 0.175 3732 6385 exclusion phecode
939.1 Contact and allergic dermatitis of eyelid Dermatologic 0.884 0.64 – 1.22 0.455 52 190 exclusion phecode
941 Adverse reaction to serum or vaccine Injuries & Poisonings 0.955 0.761 – 1.2 0.693 97 417 exclusion phecode
942 Infusion and transfusion reaction Injuries & Poisonings 1.1 0.905 – 1.33 0.341 141 550 exclusion phecode
946 Anaphylactic shock NOS Injuries & Poisonings 0.953 0.83 – 1.09 0.495 266 1128 exclusion phecode
947 Urticaria Dermatologic 0.997 0.909 – 1.09 0.949 629 2407 exclusion phecode
949 Allergies, other Injuries & Poisonings 0.996 0.954 – 1.04 0.859 3536 6385 exclusion phecode
952
Spinal cord injury without evidence of spinal
Spinal cord injury without evidence of spinal bone injury
 Injuries & Poisonings 1.05 0.889 – 1.24 0.569 172 1383 exclusion phecode
957 Injury to other and unspecified nerves Injuries & Poisonings 1.09 0.788 – 1.51 0.604 48 330 exclusion phecode
958
Certain early complications of trauma or
Certain early complications of trauma or procedure
 Injuries & Poisonings 1.02 0.925 – 1.13 0.658 461 3375 exclusion phecode
958.1 Postoperative shock Injuries & Poisonings 1.13 0.889 – 1.45 0.313 81 477 exclusion phecode
958.2 Traumatic and surgical subcutaneous emphysema Injuries & Poisonings 1.02 0.725 – 1.43 0.922 39 316 exclusion phecode
960 Poisoning by antibiotics Injuries & Poisonings 0.986 0.92 – 1.06 0.685 1006 5594 exclusion phecode
960.1
Adverse effects of antibacterials (not
Adverse effects of antibacterials (not penicillins)
 Injuries & Poisonings 1.13 0.964 – 1.32 0.132 189 937 exclusion phecode
960.2 Allergy/adverse effect of penicillin Injuries & Poisonings 0.954 0.876 – 1.04 0.278 625 3955 exclusion phecode
961 Poisoning by other anti-infectives Injuries & Poisonings 1.03 0.895 – 1.18 0.712 271 1331 exclusion phecode
961.1 Poisoning/allergy of sulfonamides Injuries & Poisonings 0.963 0.867 – 1.07 0.486 406 2584 exclusion phecode
962 Poisoning by hormones and synthetic substitutes Injuries & Poisonings 0.989 0.893 – 1.1 0.84 458 2351 exclusion phecode
962.1
Adrenal cortical steroids causing adverse
Adrenal cortical steroids causing adverse effects in therapeutic use
 Injuries & Poisonings 1 0.862 – 1.16 0.988 221 1061 exclusion phecode
962.2
Insulins and antidiabetic agents causing
Insulins and antidiabetic agents causing adverse effects in therapeutic use
 Injuries & Poisonings 0.891 0.662 – 1.2 0.443 50 301 exclusion phecode
962.3
Hormones and synthetic substitutes causing
Hormones and synthetic substitutes causing adverse effects in therapeutic use
 Injuries & Poisonings 0.997 0.872 – 1.14 0.963 258 1403 exclusion phecode
963 Poisoning by primarily systemic agents Injuries & Poisonings 1.01 0.943 – 1.09 0.745 937 5848 exclusion phecode
963.1
Antineoplastic and immunosuppressive drugs
Antineoplastic and immunosuppressive drugs causing adverse effects
 Injuries & Poisonings 1.04 0.963 – 1.11 0.346 904 5729 exclusion phecode
964
Poisoning by agents primarily affecting blood
Poisoning by agents primarily affecting blood constituents
 Injuries & Poisonings 1.01 0.909 – 1.12 0.892 466 2089 exclusion phecode
964.1 Anticoagulants causing adverse effects Injuries & Poisonings 0.987 0.889 – 1.1 0.803 444 1991 exclusion phecode
965
Poisoning by analgesics, antipyretics, and
Poisoning by analgesics, antipyretics, and antirheumatics
 Injuries & Poisonings 1.05 0.942 – 1.18 0.358 382 2105 exclusion phecode
965.1
Opiates and related narcotics causing adverse
Opiates and related narcotics causing adverse effects in therapeutic use
 Injuries & Poisonings 1.07 0.979 – 1.17 0.133 577 3464 exclusion phecode
965.3
Salicylates causing adverse effects in
Salicylates causing adverse effects in therapeutic use
 Injuries & Poisonings 1.04 0.771 – 1.4 0.798 47 302 exclusion phecode
966
Poisoning by anticonvulsants and
Poisoning by anticonvulsants and anti-Parkinsonism drugs
 Injuries & Poisonings 0.84 0.616 – 1.15 0.271 44 273 exclusion phecode
967
Adverse effects of sedatives or other central
Adverse effects of sedatives or other central nervous system depressants and anesthetics
 Injuries & Poisonings 0.961 0.87 – 1.06 0.438 469 3044 exclusion phecode
969 Poisoning by psychotropic agents Injuries & Poisonings 1.09 0.91 – 1.31 0.341 143 685 exclusion phecode
971
Poisoning by drugs primarily affecting the
Poisoning by drugs primarily affecting the autonomic nervous system
 Injuries & Poisonings 0.811 0.562 – 1.17 0.263 47 204 exclusion phecode
972
Poisoning by agents primarily affecting the
Poisoning by agents primarily affecting the cardiovascular system
 Injuries & Poisonings 0.971 0.829 – 1.14 0.712 196 803 exclusion phecode
972.1
Cardiac rhythm regulators causing adverse
Cardiac rhythm regulators causing adverse effects in therapeutic use
 Injuries & Poisonings 0.843 0.633 – 1.12 0.243 60 218 exclusion phecode
972.6 Antihypertensive agents causing adverse effects Injuries & Poisonings 0.996 0.767 – 1.29 0.979 76 304 exclusion phecode
974
Poisoning by water, mineral, and uric acid
Poisoning by water, mineral, and uric acid metabolism drugs
 Injuries & Poisonings 1.15 0.892 – 1.49 0.277 84 354 exclusion phecode
975
Poisoning by agents primarily acting on the
Poisoning by agents primarily acting on the smooth and skeletal muscles and respiratory system
 Injuries & Poisonings 0.92 0.653 – 1.3 0.634 47 204 exclusion phecode
976
Poisoning by agents primarily affecting skin &
Poisoning by agents primarily affecting skin & mucous membrane, ophthalmological, otorhinolaryngological, & dental drugs
 Injuries & Poisonings 1.37 0.936 – 2 0.105 36 192 exclusion phecode
977 Personal history of allergy to medicinal agents Injuries & Poisonings 1.02 0.94 – 1.1 0.696 813 4138 exclusion phecode
979 Adverse drug events and drug allergies Injuries & Poisonings 1.01 0.956 – 1.07 0.742 1664 7887 exclusion phecode
980
Encounter for long-term (current) use of
Encounter for long-term (current) use of antibiotics
 Infectious Diseases 1 0.915 – 1.09 0.987 567 4146 exclusion phecode
985 Toxic effect of other metals Injuries & Poisonings 1.37 0.889 – 2.12 0.152 24 181 exclusion phecode
989
Toxic effect of other substances, chiefly
Toxic effect of other substances, chiefly nonmedicinal as to source
 Injuries & Poisonings 1.12 0.874 – 1.44 0.367 82 449 exclusion phecode
990 Effects radiation NOS Injuries & Poisonings 0.992 0.928 – 1.06 0.815 1018 8384 exclusion phecode
994 Sepsis and SIRS Injuries & Poisonings 1.04 0.974 – 1.11 0.245 1098 6254 exclusion phecode
994.1 Systemic inflammatory response syndrome (SIRS) Injuries & Poisonings 1.04 0.869 – 1.25 0.648 148 868 exclusion phecode
994.2 Sepsis Injuries & Poisonings 1.04 0.975 – 1.11 0.224 1051 5976 exclusion phecode
994.21 Septic shock Injuries & Poisonings 1.03 0.913 – 1.15 0.67 345 1755 exclusion phecode
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