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Scores Triglycerides (mmol/L) Michigan Genomics Initiative Freeze 3 (MGI) PheWAS analysis

Triglycerides (mmol/L) — Michigan Genomics Initiative Freeze 3 (MGI) PRS PheWAS

PRS model
PRS ID exprsweb-triglycerides-30870-raw-prscs-mgi-freeze3-20211120Legacy PRSCSPRS-CSUK Biobank GWAS

Evaluation cohort: Michigan Genomics Initiative Freeze 3 (MGI).

This page pairs the PheWAS plot with the full sortable table for the all-subject and exclusion scans.

Read the all-subject and exclusion scans separately. The combined view is only a browsing aid, and the selected-phecode panel below is only meaningful when the same phecode exists in both scans.

ExPRS exclusion definition

Exclusion cohort: normal-range subset (0.01-150).

For this ExPRS, the exclusion sensitivity scan keeps only the study's normal-range subset for Triglycerides (mmol/L) (0.01-150) before rerunning the PheWAS. This is an exposure-based sensitivity analysis rather than a diagnosis-based exclusion.

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393 rows visible 17 categories
Phecode Description Category OR 95% CI P value Cases Controls Analysis Link
008 Intestinal infection Infectious Diseases 1 0.965 – 1.04 0.847 3004 29292 all phecode
008.5 Bacterial enteritis Infectious Diseases 1.05 0.994 – 1.12 0.0789 1322 13162 all phecode
008.52 Intestinal infection due to C. difficile Infectious Diseases 1.08 1.01 – 1.15 0.0289 1046 10455 all phecode
008.6 Viral Enteritis Infectious Diseases 0.971 0.898 – 1.05 0.456 770 7676 all phecode
010 Tuberculosis Infectious Diseases 0.889 0.774 – 1.02 0.0941 244 2425 all phecode
031 Diseases due to other mycobacteria Infectious Diseases 0.864 0.685 – 1.09 0.217 86 855 all phecode
038 Septicemia Infectious Diseases 1.1 1.05 – 1.14 2.68e-05 2582 24779 all phecode
038.1 Gram negative septicemia Infectious Diseases 1.07 0.978 – 1.17 0.138 568 5629 all phecode
038.2 Gram positive septicemia Infectious Diseases 1.09 0.945 – 1.25 0.245 235 2350 all phecode
038.3 Bacteremia Infectious Diseases 1.07 1.01 – 1.14 0.0283 1210 12079 all phecode
041 Bacterial infection NOS Infectious Diseases 1.06 1.03 – 1.09 0.000128 5750 38799 all phecode
041.1 Staphylococcus infections Infectious Diseases 1.07 1.01 – 1.13 0.013 1707 16977 all phecode
041.11 Methicillin sensitive Staphylococcus aureus Infectious Diseases 1.07 0.999 – 1.15 0.0519 920 9192 all phecode
041.12 Methicillin resistant Staphylococcus aureus Infectious Diseases 1.1 1.01 – 1.19 0.0196 783 7812 all phecode
041.2 Streptococcus infection Infectious Diseases 1.09 1.04 – 1.15 0.000963 1632 16287 all phecode
041.21 Rheumatic fever / chorea Infectious Diseases 1.08 0.94 – 1.23 0.286 257 2554 all phecode
041.4 E. coli Infectious Diseases 1.05 0.982 – 1.11 0.166 1175 11680 all phecode
041.8 H. pylori Infectious Diseases 1.02 0.891 – 1.17 0.77 257 2521 all phecode
041.9 Infection with drug-resistant microorganisms Infectious Diseases 1.07 0.958 – 1.2 0.227 387 3864 all phecode
053 Herpes zoster Infectious Diseases 0.959 0.908 – 1.01 0.134 1560 15184 all phecode
053.1 Herpes zoster with nervous system complications Infectious Diseases 0.962 0.832 – 1.11 0.597 220 2169 all phecode
054 Herpes simplex Infectious Diseases 1.02 0.963 – 1.07 0.564 1593 15600 all phecode
070 Viral hepatitis Infectious Diseases 1.06 0.985 – 1.14 0.118 829 8280 all phecode
070.1 Viral hepatitis A Infectious Diseases 1.12 0.894 – 1.41 0.32 87 860 all phecode
070.2 Viral hepatitis B Infectious Diseases 1.15 0.987 – 1.33 0.0727 215 2138 all phecode
070.3 Viral hepatitis C Infectious Diseases 1.03 0.94 – 1.13 0.512 528 5280 all phecode
070.4 Chronic hepatitis Infectious Diseases 1.19 1.02 – 1.39 0.0246 197 1964 all phecode
070.9 Hepatitis NOS Infectious Diseases 1.11 1.04 – 1.18 0.00142 1145 11381 all phecode
071 Human immunodeficiency virus [HIV] disease Infectious Diseases 1.12 0.943 – 1.33 0.198 145 1450 all phecode
071.1 HIV infection, symptomatic Infectious Diseases 1.13 0.94 – 1.37 0.189 117 1163 all phecode
078 Viral warts & HPV Infectious Diseases 0.989 0.953 – 1.03 0.554 3434 29624 all phecode
079 Viral infection Infectious Diseases 1.02 0.992 – 1.05 0.155 6664 35342 all phecode
079.1 Varicella infection Infectious Diseases 1.01 0.973 – 1.05 0.641 3793 31251 all phecode
079.2 Infectious mononucleosis Infectious Diseases 0.957 0.84 – 1.09 0.515 283 2723 all phecode
079.9 Viremia, NOS Infectious Diseases 1.07 0.998 – 1.16 0.0581 838 8253 all phecode
080 Postoperative infection Infectious Diseases 0.998 0.957 – 1.04 0.927 2619 26065 all phecode
081
Infection/inflammation of internal prosthetic
Infection/inflammation of internal prosthetic device; implant; and graft
 Infectious Diseases 1.06 1 – 1.11 0.0494 1589 15884 all phecode
090
Sexually transmitted infections (not HIV or
Sexually transmitted infections (not HIV or hepatitis)
 Infectious Diseases 0.972 0.907 – 1.04 0.426 965 9630 all phecode
110 Dermatophytosis / Dermatomycosis Infectious Diseases 1.01 0.97 – 1.04 0.738 3544 30054 all phecode
110.1 Dermatophytosis Infectious Diseases 1.02 0.978 – 1.06 0.409 3241 27244 all phecode
110.11 Dermatophytosis of nail Infectious Diseases 1.02 0.967 – 1.07 0.545 2044 16765 all phecode
110.12 Althete's foot Infectious Diseases 1.04 0.97 – 1.12 0.261 899 8043 all phecode
110.13 Dermatophytosis of the body Infectious Diseases 0.973 0.9 – 1.05 0.492 790 7827 all phecode
110.2 Dermatomycoses Infectious Diseases 0.941 0.844 – 1.05 0.271 398 3971 all phecode
112 Candidiasis Infectious Diseases 1.06 1.02 – 1.1 0.00201 3685 30495 all phecode
112.3 Candidiasis of skin and nails Infectious Diseases 1.07 0.982 – 1.16 0.124 682 6732 all phecode
117 Mycoses Infectious Diseases 1.03 0.941 – 1.12 0.543 608 6069 all phecode
117.1 Histoplasmosis Infectious Diseases 1.09 0.851 – 1.38 0.508 81 801 all phecode
117.4 Aspergillosis Infectious Diseases 1.1 0.914 – 1.32 0.321 140 1387 all phecode
130 Spirochetal infection Infectious Diseases 0.988 0.837 – 1.17 0.89 168 1677 all phecode
130.1 Lyme disease Infectious Diseases 0.902 0.739 – 1.1 0.313 116 1160 all phecode
131 Protozoan infection Infectious Diseases 1.19 0.904 – 1.56 0.217 61 610 all phecode
132 Infestation (lice, mites) Infectious Diseases 0.954 0.816 – 1.11 0.554 195 1948 all phecode
134 Helminthiases Infectious Diseases 1.17 0.921 – 1.48 0.199 83 812 all phecode
134.1 Intestinal helminthiases Infectious Diseases 1.25 0.929 – 1.67 0.142 53 513 all phecode
136 Other infectious and parasitic diseases Infectious Diseases 1.03 0.993 – 1.07 0.115 3279 32486 all phecode
145 Cancer of mouth Neoplasms 0.991 0.936 – 1.05 0.755 1481 14725 all phecode
145.1 Cancer of lip Neoplasms 1.05 0.821 – 1.35 0.695 76 750 all phecode
145.2 Cancer of tongue Neoplasms 0.975 0.895 – 1.06 0.557 645 6430 all phecode
145.3 Cancer of major salivary glands Neoplasms 0.964 0.86 – 1.08 0.526 361 3597 all phecode
145.4 Cancer of the gums Neoplasms 1 0.847 – 1.19 0.96 166 1632 all phecode
145.5 Cancer of the mouth floor Neoplasms 0.989 0.85 – 1.15 0.884 206 2048 all phecode
149 Cancer of larynx, pharynx, nasal cavities Neoplasms 0.959 0.902 – 1.02 0.169 1290 12873 all phecode
149.1 Cancer of oropharynx Neoplasms 0.895 0.797 – 1.01 0.0632 350 3499 all phecode
149.2 Cancer of nasopharynx Neoplasms 0.986 0.801 – 1.21 0.895 100 1000 all phecode
149.3 Cancer of hypopharynx Neoplasms 0.891 0.701 – 1.13 0.346 82 819 all phecode
149.4 Cancer of larynx Neoplasms 1.02 0.91 – 1.13 0.775 386 3857 all phecode
149.5
Hx of malignant neoplasm of oral cavity and
Hx of malignant neoplasm of oral cavity and pharynx
 Neoplasms 1 0.915 – 1.1 0.933 552 5505 all phecode
149.9 Cancer of of nasal cavities Neoplasms 0.888 0.773 – 1.02 0.0919 240 2398 all phecode
150 Cancer of esophagus Neoplasms 0.955 0.86 – 1.06 0.384 433 4315 all phecode
151 Cancer of stomach Neoplasms 0.927 0.841 – 1.02 0.132 498 4962 all phecode
153 Colorectal cancer Neoplasms 1.01 0.95 – 1.06 0.842 1458 14383 all phecode
153.2 Colon cancer Neoplasms 0.997 0.936 – 1.06 0.929 1160 11472 all phecode
153.3
Malignant neoplasm of rectum, rectosigmoid
Malignant neoplasm of rectum, rectosigmoid junction, and anus
 Neoplasms 1.01 0.935 – 1.09 0.821 815 8093 all phecode
155 Cancer of liver and intrahepatic bile duct Neoplasms 1.06 0.967 – 1.17 0.204 511 5097 all phecode
155.1 Malignant neoplasm of liver, primary Neoplasms 1.08 0.958 – 1.21 0.217 344 3433 all phecode
157 Pancreatic cancer Neoplasms 0.988 0.897 – 1.09 0.803 503 5005 all phecode
158
Neoplasm of unspecified nature of digestive
Neoplasm of unspecified nature of digestive system
 Neoplasms 0.981 0.93 – 1.04 0.493 1623 15759 all phecode
159
Malignant neoplasm of other and ill-defined
Malignant neoplasm of other and ill-defined sites within the digestive organs and peritoneum
 Neoplasms 0.972 0.924 – 1.02 0.278 1818 17869 all phecode
159.2
Malignant neoplasm of small intestine
Malignant neoplasm of small intestine, including duodenum
 Neoplasms 1 0.87 – 1.16 0.972 221 2206 all phecode
159.3
Malignant neoplasm of gallbladder and
Malignant neoplasm of gallbladder and extrahepatic bile ducts
 Neoplasms 0.922 0.78 – 1.09 0.339 158 1578 all phecode
159.4
Malignant neoplasm of retroperitoneum and
Malignant neoplasm of retroperitoneum and peritoneum
 Neoplasms 0.918 0.81 – 1.04 0.181 293 2920 all phecode
164 Cancer of intrathoracic organs Neoplasms 1.24 1.04 – 1.49 0.0159 133 1324 all phecode
165 Cancer within the respiratory system Neoplasms 1.03 0.975 – 1.1 0.257 1336 13340 all phecode
165.1 Cancer of bronchus; lung Neoplasms 1.04 0.975 – 1.11 0.229 1057 10552 all phecode
170 Cancer of bone and connective tissue Neoplasms 1.01 0.964 – 1.07 0.571 1792 17850 all phecode
170.1 Bone cancer Neoplasms 0.983 0.909 – 1.06 0.657 773 7690 all phecode
170.2 Cancer of connective tissue Neoplasms 1.02 0.963 – 1.09 0.448 1266 12632 all phecode
172 Skin cancer Neoplasms 1.01 0.981 – 1.03 0.611 8608 33186 all phecode
172.1 Melanomas of skin, dx or hx Neoplasms 1.01 0.975 – 1.04 0.696 5330 30106 all phecode
172.11 Melanomas of skin Neoplasms 0.993 0.954 – 1.03 0.716 3100 25064 all phecode
172.2 Other non-epithelial cancer of skin Neoplasms 1 0.973 – 1.03 0.977 7095 30462 all phecode
172.21 Basal cell carcinoma Neoplasms 0.991 0.955 – 1.03 0.632 3690 23868 all phecode
172.22 Squamous cell carcinoma Neoplasms 1.01 0.968 – 1.06 0.595 2414 17683 all phecode
172.3 Carcinoma in situ of skin Neoplasms 1.03 0.976 – 1.09 0.265 1482 12326 all phecode
173 Neoplasm of uncertain behavior of skin Neoplasms 1.04 0.991 – 1.09 0.115 1997 18755 all phecode
174 Breast cancer Neoplasms 0.954 0.916 – 0.994 0.0248 3186 15514 all phecode
174.1 Breast cancer [female] Neoplasms 0.949 0.911 – 0.99 0.015 3036 14701 all phecode
174.11 Malignant neoplasm of female breast Neoplasms 0.947 0.908 – 0.987 0.0109 2991 14639 all phecode
174.3 Neoplasm of uncertain behavior of breast Neoplasms 0.946 0.821 – 1.09 0.448 233 2307 all phecode
175 Acquired absence of breast Neoplasms 0.928 0.864 – 0.997 0.0424 919 8920 all phecode
180 Cervical cancer and dysplasia Neoplasms 0.994 0.938 – 1.05 0.826 1431 12185 all phecode
180.1 Cervical cancer Neoplasms 0.932 0.846 – 1.03 0.154 500 4982 all phecode
180.3
Cervical intraepithelial neoplasia [CIN]
Cervical intraepithelial neoplasia [CIN] [Cervical dysplasia]
 Neoplasms 0.996 0.932 – 1.07 0.918 1048 9323 all phecode
182 Malignant neoplasm of uterus Neoplasms 1.02 0.94 – 1.1 0.685 765 7613 all phecode
184 Cancer of other female genital organs Neoplasms 0.978 0.919 – 1.04 0.492 1191 11592 all phecode
184.1
Malignant neoplasm of ovary and other uterine
Malignant neoplasm of ovary and other uterine adnexa
 Neoplasms 0.929 0.849 – 1.02 0.114 573 5719 all phecode
184.11 Malignant neoplasm of ovary Neoplasms 0.904 0.815 – 1 0.0573 432 4309 all phecode
184.2
Cancer of other female genital organs
Cancer of other female genital organs (excluding uterus and ovary)
 Neoplasms 1.02 0.93 – 1.11 0.735 608 6057 all phecode
185 Cancer of prostate Neoplasms 0.96 0.918 – 1.01 0.0815 2901 10342 all phecode
187 Cancer of other male genital organs Neoplasms 1.05 0.935 – 1.18 0.398 339 3384 all phecode
187.1
Malignant neoplasm of unspecified male genital
Malignant neoplasm of unspecified male genital organ
 Neoplasms 0.989 0.81 – 1.21 0.912 115 1141 all phecode
187.2 Malignant neoplasm of testis Neoplasms 1.07 0.909 – 1.25 0.43 183 1830 all phecode
187.8
Neoplasm of uncertain behavior of male genital
Neoplasm of uncertain behavior of male genital organs
 Neoplasms 0.875 0.651 – 1.18 0.375 57 562 all phecode
189
Cancer of urinary organs (incl. kidney and
Cancer of urinary organs (incl. kidney and bladder)
 Neoplasms 1.02 0.978 – 1.06 0.367 2923 23541 all phecode
189.1 Cancer of kidney and renal pelvis Neoplasms 1.02 0.963 – 1.08 0.506 1450 14437 all phecode
189.11 Malignant neoplasm of kidney, except pelvis Neoplasms 1.03 0.972 – 1.1 0.298 1267 12655 all phecode
189.12 Malignant neoplasm of renal pelvis Neoplasms 0.998 0.869 – 1.15 0.977 237 2347 all phecode
189.2 Cancer of bladder Neoplasms 1.03 0.978 – 1.09 0.257 1783 15224 all phecode
189.21 Malignant neoplasm of bladder Neoplasms 1.03 0.973 – 1.08 0.331 1657 14178 all phecode
189.4 Malignant neoplasm of other urinary organs Neoplasms 0.998 0.917 – 1.08 0.954 678 6586 all phecode
190 Cancer of eye Neoplasms 0.886 0.734 – 1.07 0.204 138 1374 all phecode
191
Manlignant and unknown neoplasms of brain and
Manlignant and unknown neoplasms of brain and nervous system
 Neoplasms 1 0.94 – 1.07 0.903 1078 10771 all phecode
191.1 Cancer of brain and nervous system Neoplasms 1.01 0.933 – 1.1 0.784 706 7052 all phecode
191.11 Cancer of brain Neoplasms 1.04 0.953 – 1.14 0.379 600 5996 all phecode
193 Thyroid cancer Neoplasms 1.02 0.947 – 1.09 0.652 945 9393 all phecode
194 Cancer of other endocrine glands Neoplasms 0.973 0.888 – 1.06 0.548 579 5759 all phecode
195 Cancer, suspected or other Neoplasms 0.99 0.968 – 1.01 0.358 16962 26401 all phecode
195.1 Malignant neoplasm, other Neoplasms 0.99 0.968 – 1.01 0.357 16670 26384 all phecode
195.3 Malignant neoplasm of head, face, and neck Neoplasms 0.951 0.891 – 1.02 0.138 1103 9766 all phecode
196 Radiotherapy Neoplasms 0.961 0.918 – 1.01 0.0858 2427 17006 all phecode
197 Chemotherapy Neoplasms 1 0.967 – 1.03 0.979 4952 23797 all phecode
198 Secondary malignant neoplasm Neoplasms 1.01 0.982 – 1.04 0.428 5801 23481 all phecode
198.1 Secondary malignancy of lymph nodes Neoplasms 1.01 0.969 – 1.04 0.746 3677 21489 all phecode
198.2 Secondary malignancy of respiratory organs Neoplasms 1.01 0.946 – 1.08 0.744 1072 10334 all phecode
198.3
Secondary malignant neoplasm of digestive
Secondary malignant neoplasm of digestive systems
 Neoplasms 1.02 0.953 – 1.1 0.506 866 8538 all phecode
198.4 Secondary malignant neoplasm of liver Neoplasms 1.03 0.948 – 1.11 0.533 767 7558 all phecode
198.5 Secondary malignancy of brain/spine Neoplasms 0.975 0.894 – 1.06 0.562 640 6338 all phecode
198.6 Secondary malignancy of bone Neoplasms 0.963 0.894 – 1.04 0.314 866 8307 all phecode
198.7 Secondary malignant neoplasm of skin Neoplasms 0.944 0.837 – 1.06 0.342 336 3253 all phecode
199 Neoplasm of uncertain behavior Neoplasms 0.993 0.962 – 1.02 0.635 5693 25767 all phecode
199.4 Neurofibromatosis Neoplasms 0.913 0.728 – 1.15 0.431 88 880 all phecode
200 Myeloproliferative disease Neoplasms 1.12 1.05 – 1.19 0.000629 1113 11098 all phecode
200.1 Polycythemia vera Neoplasms 1.22 1.06 – 1.41 0.00576 231 2310 all phecode
201 Hodgkin's disease Neoplasms 0.92 0.779 – 1.09 0.323 172 1705 all phecode
202 Cancer of other lymphoid, histiocytic tissue Neoplasms 0.987 0.935 – 1.04 0.644 1559 15571 all phecode
202.2 Non-Hodgkins lymphoma Neoplasms 0.989 0.932 – 1.05 0.717 1329 13268 all phecode
202.21 Nodular lymphoma Neoplasms 0.953 0.878 – 1.03 0.249 693 6923 all phecode
202.22 Reticulosarcoma Neoplasms 1.06 0.9 – 1.25 0.482 170 1693 all phecode
202.24 Large cell lymphoma Neoplasms 1.05 0.884 – 1.24 0.589 160 1586 all phecode
204 Leukemia Neoplasms 1.03 0.95 – 1.12 0.459 689 6876 all phecode
204.1 Lymphoid leukemia Neoplasms 0.882 0.766 – 1.02 0.0837 236 2354 all phecode
204.11 Lymphoid leukemia, acute Neoplasms 0.909 0.71 – 1.16 0.449 74 734 all phecode
204.12 Lymphoid leukemia, chronic Neoplasms 0.85 0.72 – 1 0.055 173 1724 all phecode
204.2 Myeloid leukemia Neoplasms 1.08 0.944 – 1.23 0.265 265 2633 all phecode
204.21 Myeloid leukemia, acute Neoplasms 1.02 0.855 – 1.21 0.847 153 1516 all phecode
204.22 Myeloid leukemia, chronic Neoplasms 1.05 0.8 – 1.37 0.738 61 610 all phecode
204.4 Multiple myeloma Neoplasms 1.14 0.988 – 1.33 0.0714 217 2162 all phecode
208 Benign neoplasm of colon Neoplasms 1.01 0.991 – 1.04 0.224 10303 34953 all phecode
209 Neuroendocrine tumors Neoplasms 0.989 0.865 – 1.13 0.866 258 2580 all phecode
210 Benign neoplasm of lip, oral cavity, and pharynx Neoplasms 0.948 0.901 – 0.996 0.0344 1891 18839 all phecode
211
Benign neoplasm of other parts of digestive
Benign neoplasm of other parts of digestive system
 Neoplasms 1.03 1 – 1.05 0.0459 7329 36606 all phecode
212
Benign neoplasm of respiratory and
Benign neoplasm of respiratory and intrathoracic organs
 Neoplasms 1.01 0.958 – 1.06 0.778 1843 18412 all phecode
213 Benign neoplasm of bone and articular cartilage Neoplasms 1.02 0.963 – 1.07 0.579 1677 15527 all phecode
214 Lipoma Neoplasms 1.04 0.983 – 1.1 0.173 1437 14132 all phecode
214.1 Lipoma of skin and subcutaneous tissue Neoplasms 1.09 1.01 – 1.17 0.0283 883 8710 all phecode
215
Other benign neoplasm of connective and other
Other benign neoplasm of connective and other soft tissue
 Neoplasms 1.01 0.978 – 1.04 0.532 4528 39509 all phecode
216 Benign neoplasm of skin Neoplasms 0.99 0.968 – 1.01 0.378 11528 34919 all phecode
216.1 Screening for malignant neoplasms of the skin Neoplasms 1.03 0.874 – 1.2 0.754 174 1701 all phecode
217 Vascular hamartomas and non-neoplastic nevi Neoplasms 0.942 0.895 – 0.992 0.0224 1786 17184 all phecode
217.1 Nevus, non-neoplastic Neoplasms 0.935 0.887 – 0.986 0.0127 1679 16116 all phecode
218 Benign neoplasm of uterus Neoplasms 1.02 0.985 – 1.06 0.257 4301 16661 all phecode
218.1 Uterine leiomyoma Neoplasms 1.01 0.956 – 1.06 0.828 1835 15733 all phecode
218.2 Other benign neoplasm of uterus Neoplasms 1.02 0.982 – 1.06 0.293 3403 16447 all phecode
220 Benign neoplasm of ovary Neoplasms 1.01 0.936 – 1.08 0.869 893 8783 all phecode
221 Benign neoplasm of other female genital organs Neoplasms 1.05 0.996 – 1.1 0.0743 2042 14248 all phecode
222 Benign neoplasm of male genital organs Neoplasms 0.991 0.929 – 1.06 0.774 1133 10663 all phecode
223
Benign neoplasm of kidney and other urinary
Benign neoplasm of kidney and other urinary organs
 Neoplasms 1.02 0.97 – 1.08 0.401 1801 12657 all phecode
224 Benign neoplasm of eye Neoplasms 0.99 0.912 – 1.07 0.804 691 6752 all phecode
224.1 Benign neoplasm of eye, uveal Neoplasms 1.01 0.929 – 1.11 0.757 595 5773 all phecode
225
Benign neoplasm of brain and other parts of
Benign neoplasm of brain and other parts of nervous system
 Neoplasms 0.986 0.927 – 1.05 0.653 1209 12074 all phecode
225.1
Benign neoplasm of brain, cranial nerves
Benign neoplasm of brain, cranial nerves, meninges
 Neoplasms 0.968 0.903 – 1.04 0.37 947 9454 all phecode
225.2 Benign neoplasm of spinal cord, meninges Neoplasms 1.04 0.921 – 1.18 0.5 289 2890 all phecode
226 Benign neoplasm of thyroid glands Neoplasms 0.987 0.93 – 1.05 0.676 1329 13264 all phecode
227
Benign neoplasm of other endocrine glands and
Benign neoplasm of other endocrine glands and related structures
 Neoplasms 1 0.95 – 1.06 0.94 1690 16896 all phecode
227.1 Benign neoplasm of adrenal gland Neoplasms 1.15 1.04 – 1.27 0.00702 467 4644 all phecode
227.2 Benign neoplasm of parathyroid gland Neoplasms 0.971 0.9 – 1.05 0.458 795 7941 all phecode
227.3
Benign neoplasm of pituitary gland and
Benign neoplasm of pituitary gland and craniopharyngeal duct (pouch)
 Neoplasms 0.904 0.815 – 1 0.0564 435 4350 all phecode
228 Hemangioma and lymphangioma, any site Neoplasms 0.978 0.933 – 1.02 0.346 2149 20946 all phecode
228.1 Hemangioma of skin and subcutaneous tissue Neoplasms 0.965 0.91 – 1.02 0.237 1356 13336 all phecode
229 Benign neoplasm of unspecified sites Neoplasms 0.995 0.97 – 1.02 0.72 7767 36615 all phecode
229.1 Benign neoplasm of lymph nodes Neoplasms 0.985 0.956 – 1.01 0.309 5743 34218 all phecode
240 Simple and unspecified goiter Endocrine/metabolic 1.03 0.962 – 1.1 0.401 1031 9761 all phecode
241 Nontoxic nodular goiter Endocrine/metabolic 1.02 0.976 – 1.06 0.42 2910 22227 all phecode
241.1 Nontoxic uninodular goiter Endocrine/metabolic 1.02 0.975 – 1.07 0.374 2265 19902 all phecode
241.2 Nontoxic multinodular goiter Endocrine/metabolic 1.01 0.952 – 1.07 0.728 1304 12479 all phecode
242 Thyrotoxicosis with or without goiter Endocrine/metabolic 1.06 1 – 1.12 0.0478 1400 13425 all phecode
242.1 Graves' disease Endocrine/metabolic 1.05 0.958 – 1.16 0.28 515 5068 all phecode
242.2 Toxic multinodular goiter Endocrine/metabolic 1.18 0.978 – 1.43 0.0835 124 1224 all phecode
242.3 Exophthalmos Endocrine/metabolic 1.16 1.02 – 1.31 0.0194 292 2898 all phecode
242.31 Thyrotoxic exophthalmos Endocrine/metabolic 1.16 0.966 – 1.38 0.113 144 1432 all phecode
244 Hypothyroidism Endocrine/metabolic 1.01 0.987 – 1.04 0.308 8099 32717 all phecode
244.1 Secondary hypothyroidism Endocrine/metabolic 1 0.954 – 1.06 0.862 1762 17230 all phecode
244.2 Acquired hypothyroidism Endocrine/metabolic 0.98 0.921 – 1.04 0.516 1261 11982 all phecode
244.4 Hypothyroidism NOS Endocrine/metabolic 1.01 0.984 – 1.04 0.409 7542 32208 all phecode
245 Thyroiditis Endocrine/metabolic 0.964 0.894 – 1.04 0.35 832 7882 all phecode
245.2 Chronic thyroiditis Endocrine/metabolic 0.963 0.886 – 1.05 0.38 686 6517 all phecode
245.21 Chronic lymphocytic thyroiditis Endocrine/metabolic 0.958 0.88 – 1.04 0.316 679 6449 all phecode
246 Other disorders of thyroid Endocrine/metabolic 1.01 0.979 – 1.04 0.578 6129 30240 all phecode
246.2 Thyroid cyst Endocrine/metabolic 1.18 0.953 – 1.47 0.128 101 960 all phecode
246.7 Abnormal results of function study of thyroid Endocrine/metabolic 0.993 0.924 – 1.07 0.854 886 8696 all phecode
249 Secondary diabetes mellitus Endocrine/metabolic 1.22 1.14 – 1.32 4.37e-08 1150 8340 all phecode
250 Diabetes mellitus Endocrine/metabolic 1.14 1.12 – 1.17 1.09e-30 13947 31815 all phecode
250.1 Type 1 diabetes Endocrine/metabolic 1.16 1.09 – 1.24 1.37e-06 2364 11758 all phecode
250.11 Type 1 diabetes with ketoacidosis Endocrine/metabolic 1.26 1.05 – 1.52 0.0118 262 960 all phecode
250.12 Type 1 diabetes with renal manifestations Endocrine/metabolic 1.2 1.07 – 1.35 0.00248 551 2686 all phecode
250.13 Type 1 diabetes with ophthalmic manifestations Endocrine/metabolic 1.18 1.05 – 1.32 0.00447 784 3018 all phecode
250.14 Type 1 diabetes with neurological manifestations Endocrine/metabolic 1.16 1.03 – 1.31 0.0138 638 2675 all phecode
250.15
Diabetes type 1 with peripheral circulatory
Diabetes type 1 with peripheral circulatory disorders
 Endocrine/metabolic 1.02 0.838 – 1.25 0.823 155 850 all phecode
250.2 Type 2 diabetes Endocrine/metabolic 1.19 1.16 – 1.22 6.78e-37 9843 29688 all phecode
250.21 Type 2 diabetes with ketoacidosis Endocrine/metabolic 1.38 1.18 – 1.62 8.8e-05 282 1327 all phecode
250.22 Type 2 diabetes with renal manifestations Endocrine/metabolic 1.28 1.21 – 1.35 6.64e-17 1941 13510 all phecode
250.23 Type 2 diabetes with ophthalmic manifestations Endocrine/metabolic 1.18 1.11 – 1.27 8.29e-07 1643 9668 all phecode
250.24 Type 2 diabetes with neurological manifestations Endocrine/metabolic 1.25 1.18 – 1.31 5.79e-17 2557 16502 all phecode
250.25
Diabetes type 2 with peripheral circulatory
Diabetes type 2 with peripheral circulatory disorders
 Endocrine/metabolic 1.3 1.2 – 1.42 1.75e-09 860 6143 all phecode
250.3 Insulin pump user Endocrine/metabolic 1.26 1.2 – 1.31 7.98e-23 3496 20809 all phecode
250.4 Abnormal glucose Endocrine/metabolic 1.11 1.08 – 1.14 5.94e-13 8385 30645 all phecode
250.41 Impaired fasting glucose Endocrine/metabolic 1.1 1.04 – 1.16 0.000404 1870 15861 all phecode
250.42 Other abnormal glucose Endocrine/metabolic 1.11 1.08 – 1.14 3.63e-12 7553 30071 all phecode
250.5 Glycosuria or Acetonuria Endocrine/metabolic 1.22 1.01 – 1.48 0.0409 136 1067 all phecode
250.6 Polyneuropathy in diabetes Endocrine/metabolic 1.25 1.18 – 1.32 7.65e-14 2132 13390 all phecode
250.7 Diabetic retinopathy Endocrine/metabolic 1.07 1.01 – 1.14 0.0165 1691 10517 all phecode
251 Other disorders of pancreatic internal secretion Endocrine/metabolic 1.03 0.963 – 1.11 0.367 991 8469 all phecode
251.1 Hypoglycemia Endocrine/metabolic 1.14 1.06 – 1.23 0.000259 1207 8570 all phecode
252 Disorders of parathyroid gland Endocrine/metabolic 0.985 0.942 – 1.03 0.525 2282 22119 all phecode
252.1 Hyperparathyroidism Endocrine/metabolic 0.975 0.93 – 1.02 0.305 2088 20335 all phecode
252.2 Hypoparathyroidism Endocrine/metabolic 1.05 0.953 – 1.15 0.331 508 5073 all phecode
253
Disorders of the pituitary gland and its
Disorders of the pituitary gland and its hypothalamic control
 Endocrine/metabolic 0.961 0.893 – 1.03 0.285 859 8544 all phecode
253.1 Pituitary hyperfunction Endocrine/metabolic 0.916 0.804 – 1.04 0.184 263 2621 all phecode
253.11 Acromegaly and gigantism Endocrine/metabolic 0.843 0.666 – 1.07 0.153 83 826 all phecode
253.2 Pituitary hypofunction Endocrine/metabolic 1.05 0.912 – 1.21 0.49 226 2250 all phecode
253.3 Diabetes insipidus Endocrine/metabolic 1.15 0.916 – 1.45 0.224 86 860 all phecode
253.4 Anterior pituitary disorders Endocrine/metabolic 1.09 0.904 – 1.32 0.361 121 1209 all phecode
253.7 Other disorders of neurohypophysis Endocrine/metabolic 0.991 0.803 – 1.22 0.932 108 1080 all phecode
255 Disorders of adrenal glands Endocrine/metabolic 1.07 1.01 – 1.13 0.0174 1506 14869 all phecode
255.1 Adrenal hyperfunction Endocrine/metabolic 1.13 1.01 – 1.26 0.0396 373 3730 all phecode
255.11 Cushing's syndrome Endocrine/metabolic 1.07 0.913 – 1.26 0.394 183 1830 all phecode
255.12 Hyperaldosteronism Endocrine/metabolic 1.38 1.15 – 1.66 0.000519 135 1350 all phecode
255.2 Adrenal hypofunction Endocrine/metabolic 1.04 0.952 – 1.13 0.393 626 6239 all phecode
255.21 Glucocorticoid deficiency Endocrine/metabolic 1.04 0.949 – 1.13 0.427 596 5941 all phecode
256 Ovarian dysfunction Endocrine/metabolic 1.04 0.972 – 1.1 0.277 1146 10513 all phecode
256.4 Polycystic ovaries Endocrine/metabolic 1.08 0.993 – 1.17 0.072 742 7128 all phecode
257 Testicular dysfunction Endocrine/metabolic 1.03 0.965 – 1.11 0.352 1015 9238 all phecode
257.1 Testicular hypofunction Endocrine/metabolic 1.04 0.971 – 1.12 0.254 983 8933 all phecode
258 Iatrogenic endocrine disorders Endocrine/metabolic 1.32 1.06 – 1.63 0.0133 91 910 all phecode
258.1 Postablative ovarian failure Endocrine/metabolic 0.98 0.794 – 1.21 0.848 109 1090 all phecode
259 Other endocrine disorders Endocrine/metabolic 1.03 0.96 – 1.1 0.446 1038 10259 all phecode
260 Protein-calorie malnutrition Endocrine/metabolic 1.03 0.988 – 1.07 0.17 2880 26812 all phecode
260.1 Cachexia Endocrine/metabolic 1.13 0.997 – 1.29 0.0561 292 2911 all phecode
260.2 severe protein-calorie malnutrition Endocrine/metabolic 1.04 0.982 – 1.09 0.198 1691 16847 all phecode
260.22 Nutritional marasmus Endocrine/metabolic 1.06 0.97 – 1.16 0.201 614 6140 all phecode
260.3 Adult failure to thrive Endocrine/metabolic 1 0.921 – 1.09 0.927 629 6236 all phecode
260.6 Anorexia Endocrine/metabolic 1.06 0.986 – 1.14 0.114 868 8591 all phecode
260.7 Polyphagia Endocrine/metabolic 1.05 0.807 – 1.36 0.722 65 643 all phecode
261 Vitamin deficiency Endocrine/metabolic 1.06 1.04 – 1.09 5.41e-06 7718 35203 all phecode
261.1 Vitamin A deficiency Endocrine/metabolic 1.27 0.996 – 1.63 0.0543 69 690 all phecode
261.2 Vitamin B-complex deficiencies Endocrine/metabolic 1.07 0.994 – 1.15 0.073 857 8405 all phecode
261.4 Vitamin D deficiency Endocrine/metabolic 1.06 1.03 – 1.09 1.65e-05 7255 35225 all phecode
261.41 Rickets or osteomalacia Endocrine/metabolic 1.13 0.855 – 1.51 0.382 52 511 all phecode
262 Mineral deficiency NEC Endocrine/metabolic 1.08 1.01 – 1.15 0.0191 1182 11676 all phecode
263 Other nutritional deficiency Endocrine/metabolic 1.04 0.986 – 1.1 0.15 1651 15788 all phecode
264 Lack of normal physiological development Endocrine/metabolic 0.965 0.838 – 1.11 0.624 239 2301 all phecode
264.2 Failure to thrive (childhood) Endocrine/metabolic 1.05 0.864 – 1.28 0.615 122 1220 all phecode
264.9
Lack of normal physiological development
Lack of normal physiological development, unspecified
 Endocrine/metabolic 0.862 0.68 – 1.09 0.222 81 772 all phecode
269 Proteinuria Endocrine/metabolic 1.1 1.04 – 1.16 0.000717 1694 13981 all phecode
270
Disorders of protein plasma/amino-acid
Disorders of protein plasma/amino-acid transport and metabolism
 Endocrine/metabolic 1.01 0.944 – 1.09 0.734 967 9575 all phecode
270.1 Disturbances of amino-acid transport Endocrine/metabolic 1.03 0.874 – 1.21 0.742 170 1697 all phecode
270.11
Disturbances of sulphur-bearing amino-acid
Disturbances of sulphur-bearing amino-acid metabolism
 Endocrine/metabolic 0.901 0.751 – 1.08 0.263 134 1334 all phecode
270.2 Disorders of amino-acid metabolism Endocrine/metabolic 1.01 0.811 – 1.26 0.924 96 954 all phecode
270.3 Disorders of plasma protein metabolism Endocrine/metabolic 1.01 0.931 – 1.09 0.833 737 7303 all phecode
270.32 Paraproteinemia Endocrine/metabolic 1.04 0.927 – 1.16 0.535 384 3781 all phecode
270.33 Amyloidosis Endocrine/metabolic 1.19 0.929 – 1.53 0.167 71 695 all phecode
270.34 Alpha-1-antitrypsin deficiency Endocrine/metabolic 0.989 0.755 – 1.3 0.939 69 690 all phecode
270.38
Other specified disorders of plasma protein
Other specified disorders of plasma protein metabolism
 Endocrine/metabolic 0.986 0.872 – 1.12 0.823 299 2984 all phecode
271
Disorders of carbohydrate transport and
Disorders of carbohydrate transport and metabolism
 Endocrine/metabolic 1.02 0.981 – 1.06 0.314 2907 28132 all phecode
271.3
Intestinal disaccharidase deficiencies and
Intestinal disaccharidase deficiencies and disaccharide malabsorption
 Endocrine/metabolic 1.02 0.98 – 1.06 0.327 2827 27425 all phecode
271.9
Other disorders of carbohydrate transport and
Other disorders of carbohydrate transport and metabolism
 Endocrine/metabolic 0.927 0.747 – 1.15 0.492 102 1007 all phecode
272 Disorders of lipoid metabolism Endocrine/metabolic 1.27 1.24 – 1.3 4.37e-102 18881 26670 all phecode
272.1 Hyperlipidemia Endocrine/metabolic 1.27 1.24 – 1.3 3.47e-102 18843 26654 all phecode
272.11 Hypercholesterolemia Endocrine/metabolic 1.26 1.22 – 1.3 2.7e-44 5928 21600 all phecode
272.12 Hyperglyceridemia Endocrine/metabolic 1.99 1.87 – 2.12 3.41e-104 1360 11837 all phecode
272.13 Mixed hyperlipidemia Endocrine/metabolic 1.36 1.3 – 1.41 1.71e-47 3538 18449 all phecode
272.9 Unspecified disorder of lipoid metabolism Endocrine/metabolic 1.17 1.03 – 1.32 0.0133 313 3011 all phecode
274 Gout and other crystal arthropathies Endocrine/metabolic 1.12 1.07 – 1.17 4.78e-07 2524 22729 all phecode
274.1 Gout Endocrine/metabolic 1.13 1.08 – 1.18 4.96e-08 2409 21991 all phecode
274.11 Gouty arthropathy Endocrine/metabolic 1.14 1.07 – 1.22 0.000128 1082 10576 all phecode
274.2 Crystal arthropathies Endocrine/metabolic 0.953 0.816 – 1.11 0.54 195 1890 all phecode
274.21 Chondrocalcinosis Endocrine/metabolic 0.968 0.826 – 1.14 0.691 183 1772 all phecode
275 Disorders of mineral metabolism Endocrine/metabolic 1.02 0.991 – 1.06 0.159 4357 37091 all phecode
275.1 Disorders of iron metabolism Hematopoietic 1.12 0.971 – 1.29 0.12 218 2180 all phecode
275.11 Hereditary hemochromatosis Hematopoietic 0.984 0.794 – 1.22 0.881 99 990 all phecode
275.2 Disorders of copper metabolism Endocrine/metabolic 1.1 0.853 – 1.43 0.455 62 614 all phecode
275.3 Disorders of magnesium metabolism Endocrine/metabolic 1.05 0.981 – 1.11 0.172 1154 11504 all phecode
275.5 Disorders of calcium/phosphorus metabolism Endocrine/metabolic 1.02 0.978 – 1.05 0.433 3369 31544 all phecode
275.51 Hypocalcemia Endocrine/metabolic 1.02 0.953 – 1.1 0.515 898 8969 all phecode
275.53 Disorders of phosphorus metabolism Endocrine/metabolic 1.02 0.959 – 1.08 0.566 1366 13634 all phecode
275.6 Hypercalcemia Endocrine/metabolic 1.07 1.01 – 1.13 0.0162 1468 14183 all phecode
276
Disorders of fluid, electrolyte, and acid-base
Disorders of fluid, electrolyte, and acid-base balance
 Endocrine/metabolic 1.06 1.03 – 1.08 8.89e-06 9238 37046 all phecode
276.1 Electrolyte imbalance Endocrine/metabolic 1.07 1.04 – 1.1 2.02e-06 6352 34366 all phecode
276.11 Hyperosmolality and/or hypernatremia Endocrine/metabolic 1.1 1 – 1.2 0.0511 550 5434 all phecode
276.12 Hyposmolality and/or hyponatremia Endocrine/metabolic 1.06 1.01 – 1.1 0.0115 2514 23219 all phecode
276.13 Hyperpotassemia Endocrine/metabolic 1.08 1.03 – 1.12 0.000315 2992 25216 all phecode
276.14 Hypopotassemia Endocrine/metabolic 1.06 1.02 – 1.11 0.00968 2148 20909 all phecode
276.4 Acid-base balance disorder Endocrine/metabolic 1.1 1.05 – 1.15 7.09e-05 2086 20332 all phecode
276.41 Acidosis Endocrine/metabolic 1.11 1.05 – 1.16 9.77e-05 1788 17572 all phecode
276.42 Alkalosis Endocrine/metabolic 1.04 0.942 – 1.15 0.435 476 4741 all phecode
276.5 Hypovolemia Endocrine/metabolic 1.05 1.01 – 1.08 0.00707 4574 34527 all phecode
276.6 Fluid overload Endocrine/metabolic 1.05 0.991 – 1.11 0.0964 1384 13211 all phecode
276.8 Polydipsia Endocrine/metabolic 1.19 0.987 – 1.44 0.0674 124 1240 all phecode
277 Other disorders of metabolism Endocrine/metabolic 1.06 1.03 – 1.1 0.000313 4112 35070 all phecode
277.2
Other disorders of purine and pyrimidine
Other disorders of purine and pyrimidine metabolism
 Endocrine/metabolic 1.08 0.971 – 1.21 0.155 403 3991 all phecode
277.4 Disorders of bilirubin excretion Endocrine/metabolic 0.978 0.902 – 1.06 0.586 720 7161 all phecode
277.5 Other disorders of lipoid metabolism Endocrine/metabolic 1.16 1.08 – 1.25 4e-05 936 9270 all phecode
277.51 Lipoprotein disorders Endocrine/metabolic 1.2 1.11 – 1.3 6.02e-06 773 7668 all phecode
277.7 Dysmetabolic syndrome X Endocrine/metabolic 1.19 1.11 – 1.28 1.85e-06 916 8359 all phecode
278 Overweight, obesity and other hyperalimentation Endocrine/metabolic 1.06 1.04 – 1.08 1.39e-09 19419 27331 all phecode
278.1 Obesity Endocrine/metabolic 1.07 1.05 – 1.09 4.69e-11 17129 27321 all phecode
278.11 Morbid obesity Endocrine/metabolic 1.07 1.04 – 1.1 1.23e-06 8280 27172 all phecode
278.3 Localized adiposity Endocrine/metabolic 1.09 0.969 – 1.22 0.151 324 3228 all phecode
278.4 Abnormal weight gain Endocrine/metabolic 1.05 1 – 1.1 0.0402 2104 17411 all phecode
279 Disorders involving the immune mechanism Endocrine/metabolic 1.03 0.994 – 1.08 0.101 2934 28612 all phecode
279.1 Immunity deficiency Endocrine/metabolic 0.985 0.924 – 1.05 0.639 1161 11571 all phecode
279.11 Deficiency of humoral immunity Endocrine/metabolic 1 0.888 – 1.13 0.976 330 3278 all phecode
279.2 Autoimmune disease NEC Endocrine/metabolic 1.04 0.963 – 1.13 0.315 754 7516 all phecode
279.7 Other immunological findings Endocrine/metabolic 1.03 1 – 1.07 0.0343 4885 36552 all phecode
279.8
Other specified disorders involving the immune
Other specified disorders involving the immune mechanism
 Endocrine/metabolic 1.07 0.984 – 1.17 0.112 601 5988 all phecode
280 Iron deficiency anemias Hematopoietic 1.04 1.01 – 1.08 0.0118 4626 30873 all phecode
280.1
Iron deficiency anemias, unspecified or not due
Iron deficiency anemias, unspecified or not due to blood loss
 Hematopoietic 1.05 1.01 – 1.08 0.00844 4484 30649 all phecode
280.2
Iron deficiency anemia secondary to blood loss
Iron deficiency anemia secondary to blood loss (chronic)
 Hematopoietic 1.05 0.995 – 1.1 0.0735 1771 17196 all phecode
281 Other deficiency anemia Hematopoietic 1.02 0.93 – 1.12 0.646 519 5120 all phecode
281.1 Megaloblastic anemia Hematopoietic 1.09 0.951 – 1.25 0.214 253 2497 all phecode
281.11 Pernicious anemia Hematopoietic 1.08 0.876 – 1.32 0.483 114 1108 all phecode
281.12 Other vitamin B12 deficiency anemia Hematopoietic 1.02 0.874 – 1.2 0.764 187 1817 all phecode
281.9 Deficiency anemias Hematopoietic 1.05 0.926 – 1.2 0.434 285 2830 all phecode
282 Hereditary hemolytic anemias Hematopoietic 0.993 0.88 – 1.12 0.906 323 3188 all phecode
282.8 Other hemoglobinopathies Hematopoietic 0.978 0.844 – 1.13 0.768 216 2113 all phecode
282.9 Other hereditary hemolytic anemias Hematopoietic 1.09 0.932 – 1.27 0.282 192 1920 all phecode
283 Acquired hemolytic anemias Hematopoietic 1.09 0.918 – 1.3 0.317 155 1550 all phecode
283.1 Autoimmune hemolytic anemias Hematopoietic 1.01 0.777 – 1.32 0.921 64 633 all phecode
284 Aplastic anemia Hematopoietic 1.14 1.05 – 1.24 0.00138 697 6943 all phecode
284.1 Pancytopenia Hematopoietic 1.16 1.06 – 1.26 0.00113 612 6100 all phecode
285 Other anemias Hematopoietic 1.05 1.02 – 1.07 4.82e-05 11794 33591 all phecode
285.1 Acute posthemorrhagic anemia Hematopoietic 1.07 1.03 – 1.11 0.00059 3325 27709 all phecode
285.2 Anemia of chronic disease Hematopoietic 1.07 1.02 – 1.13 0.0039 2055 19939 all phecode
285.21 Anemia in chronic kidney disease Hematopoietic 1.11 1.04 – 1.2 0.00332 932 9106 all phecode
285.22 Anemia in neoplastic disease Hematopoietic 0.972 0.896 – 1.05 0.492 690 6892 all phecode
286 Coagulation defects Hematopoietic 1.02 0.981 – 1.05 0.371 3844 33384 all phecode
286.1 Congenital coagulation defects Hematopoietic 1.01 0.878 – 1.16 0.916 250 2466 all phecode
286.11 Von willebrand's disease Hematopoietic 0.935 0.741 – 1.18 0.569 83 822 all phecode
286.12
Congenital deficiency of other clotting factors
Congenital deficiency of other clotting factors (including factor VII)
 Hematopoietic 1.03 0.846 – 1.25 0.784 126 1260 all phecode
286.2
Encounter for long-term (current) use of
Encounter for long-term (current) use of anticoagulants
 Hematopoietic 1.01 0.969 – 1.05 0.745 3354 25918 all phecode
286.3
Coagulation defects complicating pregnancy or
Coagulation defects complicating pregnancy or postpartum
 Hematopoietic 0.861 0.692 – 1.07 0.179 97 962 all phecode
286.4 Acquired coagulation factor deficiency Hematopoietic 1.13 0.986 – 1.29 0.0787 254 2529 all phecode
286.5
Hemorrhagic disorder due to intrinsic
Hemorrhagic disorder due to intrinsic circulating anticoagulants
 Hematopoietic 0.908 0.75 – 1.1 0.32 132 1294 all phecode
286.6 Defibrination syndrome Hematopoietic 0.998 0.956 – 1.04 0.908 2579 25377 all phecode
286.7 Other and unspecified coagulation defects Hematopoietic 1.01 0.972 – 1.05 0.593 3014 29294 all phecode
286.8 Hypercoagulable state Hematopoietic 1.03 0.954 – 1.11 0.473 846 8437 all phecode
286.81 Primary hypercoagulable state Hematopoietic 1.02 0.944 – 1.1 0.642 813 8111 all phecode
286.9 Abnormal coagulation profile Hematopoietic 1.02 0.959 – 1.09 0.516 1182 11487 all phecode
287 Purpura and other hemorrhagic conditions Hematopoietic 1.05 1.01 – 1.09 0.0109 3288 28474 all phecode
287.1 Spontaneous ecchymoses Hematopoietic 1.02 0.881 – 1.19 0.77 211 2094 all phecode
287.3 Thrombocytopenia Hematopoietic 1.06 1.01 – 1.1 0.00739 2938 26323 all phecode
287.31 Primary thrombocytopenia Hematopoietic 1.01 0.924 – 1.1 0.839 601 5994 all phecode
287.32 Secondary thrombocytopenia Hematopoietic 1 0.913 – 1.1 0.997 569 5686 all phecode
287.4 Qualitative platelet defects Hematopoietic 1.27 1.03 – 1.55 0.0238 112 1120 all phecode
288 Diseases of white blood cells Hematopoietic 1.03 1 – 1.07 0.04 4886 36527 all phecode
288.1 Decreased white blood cell count Hematopoietic 0.999 0.946 – 1.05 0.966 1599 15951 all phecode
288.11 Neutropenia Hematopoietic 1.04 0.974 – 1.11 0.238 1106 11041 all phecode
288.2 Elevated white blood cell count Hematopoietic 1.04 1 – 1.07 0.0435 4082 35079 all phecode
288.3 Eosinophilia Hematopoietic 1.04 0.893 – 1.22 0.583 187 1866 all phecode
289 Other diseases of blood and blood-forming organs Hematopoietic 0.98 0.93 – 1.03 0.434 1757 17434 all phecode
289.3
Personal history of diseases of blood and
Personal history of diseases of blood and blood-forming organs
 Hematopoietic 0.937 0.872 – 1.01 0.0745 918 9087 all phecode
289.4 Lymphadenitis Hematopoietic 1.01 0.979 – 1.05 0.461 3888 34715 all phecode
289.5 Diseases of spleen Hematopoietic 0.978 0.876 – 1.09 0.698 393 3913 all phecode
289.8 Polycythemia, secondary Hematopoietic 1.13 0.989 – 1.29 0.0723 255 2550 all phecode
289.9 Abnormality of red blood cells Hematopoietic 1.06 0.953 – 1.19 0.274 385 3813 all phecode
290
Delirium dementia and amnestic and other
Delirium dementia and amnestic and other cognitive disorders
 Mental Disorders 1.06 1 – 1.13 0.043 1318 11547 all phecode
290.1 Dementias Mental Disorders 0.999 0.91 – 1.1 0.984 541 4910 all phecode
290.11 Alzheimer's disease Mental Disorders 0.946 0.797 – 1.12 0.529 151 1389 all phecode
290.12 Dementia with cerebral degenerations Mental Disorders 0.944 0.749 – 1.19 0.624 88 846 all phecode
290.13 Senile dementia Mental Disorders 0.972 0.864 – 1.09 0.635 340 3078 all phecode
290.16 Vascular dementia Mental Disorders 1.06 0.834 – 1.35 0.622 81 777 all phecode
290.2 Delirium due to conditions classified elsewhere Mental Disorders 1.09 1.01 – 1.18 0.0301 750 7358 all phecode
290.3
Other persistent mental disorders due to
Other persistent mental disorders due to conditions classified elsewhere
 Mental Disorders 1.06 0.989 – 1.14 0.0953 886 8618 all phecode
291
Other specified nonpsychotic and/or transient
Other specified nonpsychotic and/or transient mental disorders
 Mental Disorders 1.05 1 – 1.09 0.0426 2550 24810 all phecode
291.1
Transient mental disorders due to conditions
Transient mental disorders due to conditions classified elsewhere
 Mental Disorders 0.857 0.725 – 1.01 0.0722 175 1750 all phecode
291.4
Specific nonpsychotic mental disorders due to
Specific nonpsychotic mental disorders due to brain damage
 Mental Disorders 1.05 0.953 – 1.16 0.307 484 4807 all phecode
291.8 Alteration of consciousness Mental Disorders 1.07 1.02 – 1.12 0.00725 2036 19974 all phecode
292 Neurological disorders Mental Disorders 1.06 1.03 – 1.1 3.77e-05 5733 38553 all phecode
292.1 Aphasia/speech disturbance Mental Disorders 1.03 0.978 – 1.08 0.297 2013 19867 all phecode
292.11 Aphasia Mental Disorders 1.03 0.95 – 1.12 0.444 664 6581 all phecode
292.12 Symbolic dysfunction Mental Disorders 1.07 0.914 – 1.24 0.418 200 1988 all phecode
292.2 Mild cognitive impairment Mental Disorders 1.06 0.95 – 1.19 0.291 389 3731 all phecode
292.3 Memory loss Mental Disorders 1.06 1.01 – 1.11 0.023 1922 18158 all phecode
292.4 Altered mental status Mental Disorders 1.08 1.04 – 1.13 0.000316 2454 22725 all phecode
292.5 Transient alteration of awareness Mental Disorders 0.999 0.903 – 1.11 0.982 430 4285 all phecode
292.6 Hallucinations Mental Disorders 1.02 0.881 – 1.17 0.825 217 2147 all phecode
293 Symptoms involving head and neck Mental Disorders 0.911 0.819 – 1.01 0.0855 414 4127 all phecode
293.1
Swelling, mass, or lump in head and neck
Swelling, mass, or lump in head and neck [Space-occupying lesion, intracranial NOS]
 Mental Disorders 1.02 0.989 – 1.06 0.199 4417 38609 all phecode
295 Schizophrenia and other psychotic disorders Mental Disorders 1.08 1.01 – 1.16 0.0359 885 8229 all phecode
295.1 Schizophrenia Mental Disorders 1.12 0.934 – 1.34 0.223 138 1339 all phecode
295.2 Paranoid disorders Mental Disorders 1.16 0.946 – 1.42 0.155 118 1079 all phecode
295.3 Psychosis Mental Disorders 1.04 0.961 – 1.13 0.317 716 6694 all phecode
296 Mood disorders Mental Disorders 1.07 1.05 – 1.1 3.08e-10 15356 20858 all phecode
296.1 Bipolar Mental Disorders 1.1 1.04 – 1.17 0.00134 1301 11264 all phecode
296.2 Depression Mental Disorders 1.07 1.05 – 1.1 2.08e-09 14833 20856 all phecode
296.22 Major depressive disorder Mental Disorders 1.07 1.05 – 1.1 2.07e-09 13850 20853 all phecode
297 Suicidal ideation or attempt Mental Disorders 1.05 0.98 – 1.13 0.167 985 9050 all phecode
297.1 Suicidal ideation Mental Disorders 1.05 0.972 – 1.14 0.212 788 7310 all phecode
297.2 Suicide or self-inflicted injury Mental Disorders 1.1 0.97 – 1.26 0.132 285 2654 all phecode
300 Anxiety disorders Mental Disorders 1.06 1.03 – 1.08 2.22e-06 15419 20850 all phecode
300.1 Anxiety disorder Mental Disorders 1.05 1.03 – 1.08 7.45e-06 14517 20855 all phecode
300.11 Generalized anxiety disorder Mental Disorders 1.05 1.01 – 1.08 0.00588 5546 20512 all phecode
300.12 Agorophobia, social phobia, and panic disorder Mental Disorders 1.06 0.999 – 1.13 0.0541 1360 11377 all phecode
300.13 Phobia Mental Disorders 1.02 0.955 – 1.1 0.513 1051 9542 all phecode
300.3 Obsessive-compulsive disorders Mental Disorders 0.945 0.84 – 1.06 0.354 328 3018 all phecode
300.4 Dysthymic disorder Mental Disorders 1.08 1.03 – 1.13 0.00164 2420 16552 all phecode
300.8 Acute reaction to stress Mental Disorders 1.01 0.916 – 1.11 0.856 504 4825 all phecode
300.9 Posttraumatic stress disorder Mental Disorders 1.09 1.01 – 1.18 0.0227 843 7909 all phecode
301 Personality disorders Mental Disorders 1.15 1.04 – 1.28 0.00486 477 4539 all phecode
301.2 Antisocial/borderline personality disorder Mental Disorders 1.09 0.953 – 1.25 0.205 254 2393 all phecode
302 Sexual and gender identity disorders Mental Disorders 1.01 0.968 – 1.05 0.742 3700 13808 all phecode
302.1 Decreased libido Mental Disorders 1.02 0.921 – 1.13 0.692 447 4331 all phecode
303 Psychogenic and somatoform disorders Mental Disorders 1.03 0.996 – 1.06 0.0892 6808 20043 all phecode
303.1 Dissociative disorder Mental Disorders 1.06 0.894 – 1.25 0.522 161 1573 all phecode
303.3 Psychogenic disorder Mental Disorders 1.02 0.988 – 1.05 0.232 6487 19888 all phecode
303.31
Gastrointestinal malfunction arising from
Gastrointestinal malfunction arising from mental factors
 Mental Disorders 0.978 0.885 – 1.08 0.664 471 4623 all phecode
303.4 Somatoform disorder Mental Disorders 1.02 0.96 – 1.09 0.494 1177 11180 all phecode
304 Adjustment reaction Mental Disorders 1.04 1 – 1.08 0.0352 3888 20475 all phecode
305.2 Eating disorder Mental Disorders 1.02 0.952 – 1.1 0.534 901 8329 all phecode
306 Other mental disorder Mental Disorders 1.04 0.987 – 1.09 0.148 1815 14133 all phecode
306.1 Mental disorders durring/after pregnancy Mental Disorders 1.03 0.941 – 1.13 0.5 587 3527 all phecode
306.9 Tension headache Mental Disorders 1.02 0.945 – 1.11 0.574 753 7277 all phecode
312 Conduct disorders Mental Disorders 1.07 0.93 – 1.22 0.358 254 2501 all phecode
312.3 Impulse control disorder Mental Disorders 0.902 0.703 – 1.16 0.419 74 736 all phecode
313 Pervasive developmental disorders Mental Disorders 1.01 0.956 – 1.07 0.728 1571 14633 all phecode
313.1 Attention deficit hyperactivity disorder Mental Disorders 0.999 0.943 – 1.06 0.982 1392 13190 all phecode
313.2 Tics and stuttering Mental Disorders 1.21 0.955 – 1.54 0.114 77 770 all phecode
313.3 Autism Mental Disorders 1.07 0.823 – 1.39 0.618 64 621 all phecode
315 Develomental delays and disorders Mental Disorders 1.06 0.978 – 1.15 0.152 684 6788 all phecode
315.1 Learning disorder Mental Disorders 0.942 0.753 – 1.18 0.599 87 860 all phecode
315.2 Speech and language disorder Mental Disorders 1.08 0.941 – 1.23 0.28 254 2539 all phecode
316 Substance addiction and disorders Mental Disorders 1.06 1.02 – 1.1 0.000952 3682 32680 all phecode
316.1 Polyneuropathy due to drugs Mental Disorders 0.992 0.911 – 1.08 0.86 634 6331 all phecode
317 Alcohol-related disorders Mental Disorders 1.02 0.973 – 1.06 0.476 2525 22920 all phecode
317.1 Alcoholism Mental Disorders 1.01 0.965 – 1.06 0.612 1986 19339 all phecode
317.11 Alcoholic liver damage Mental Disorders 1.06 0.955 – 1.18 0.264 408 4080 all phecode
318 Tobacco use disorder Mental Disorders 1.09 1.07 – 1.12 1.15e-12 8622 34842 all phecode
320 Meningitis Neurological 1 0.897 – 1.12 0.962 382 3820 all phecode
323 Encephalitis Neurological 0.925 0.783 – 1.09 0.355 181 1809 all phecode
323.8 Encephalitis, non-infectious Neurological 0.904 0.756 – 1.08 0.265 153 1527 all phecode
324 Other CNS infection and poliomyelitis Neurological 1.02 0.902 – 1.16 0.731 288 2880 all phecode
325
Phlebitis and thrombophlebitis of intracranial
Phlebitis and thrombophlebitis of intracranial venous sinuses
 Neurological 1.01 0.754 – 1.35 0.953 53 530 all phecode
327 Sleep disorders Neurological 1.05 1.03 – 1.08 6.25e-07 14941 31602 all phecode
327.1 Hypersomnia Neurological 1.05 1 – 1.1 0.0435 2061 19110 all phecode
327.3 Sleep apnea Neurological 1.06 1.04 – 1.09 6.41e-07 10909 31304 all phecode
327.31 Central/nonobstroctive sleep apnea Neurological 0.937 0.85 – 1.03 0.188 492 4784 all phecode
327.32 Obstructive sleep apnea Neurological 1.06 1.03 – 1.08 2.79e-05 8744 30530 all phecode
327.4 Insomnia Neurological 1.05 1.02 – 1.08 0.00119 5524 30960 all phecode
327.41 Organic or persistent insomnia Neurological 1.06 0.993 – 1.12 0.0832 1265 12120 all phecode
327.5 Parasomnia Neurological 1.02 0.934 – 1.11 0.676 604 5913 all phecode
327.6 Circadian rhythm sleep disorder Neurological 0.97 0.853 – 1.1 0.649 274 2666 all phecode
327.7 Sleep related movement disorders Neurological 1.03 0.983 – 1.09 0.195 1786 17323 all phecode
327.71 Restless legs syndrome Neurological 1.04 0.988 – 1.1 0.123 1570 15360 all phecode
327.72 Sleep related leg cramps Neurological 0.815 0.648 – 1.03 0.0812 83 822 all phecode
331 Other cerebral degenerations Neurological 0.994 0.916 – 1.08 0.878 717 7024 all phecode
331.1 Hydrocephalus Neurological 1.01 0.888 – 1.14 0.906 284 2836 all phecode
331.9 Cerebral degeneration, unspecified Neurological 0.982 0.883 – 1.09 0.737 419 4026 all phecode
332 Parkinson's disease Neurological 1.05 0.947 – 1.17 0.341 415 4128 all phecode
333
Extrapyramidal disease and abnormal movement
Extrapyramidal disease and abnormal movement disorders
 Neurological 1 0.961 – 1.04 0.956 2868 26583 all phecode
333.1 Essential tremor Neurological 0.963 0.888 – 1.04 0.367 725 7163 all phecode
333.2 Myoclonus Neurological 0.953 0.806 – 1.13 0.574 159 1590 all phecode
333.4 Torsion dystonia Neurological 0.97 0.863 – 1.09 0.606 352 3504 all phecode
333.8 Other degenerative diseases of the basal ganglia Neurological 0.866 0.688 – 1.09 0.221 89 890 all phecode
334 Degenerative disease of the spinal cord Neurological 0.975 0.913 – 1.04 0.465 1058 10562 all phecode
334.1 Spinocerebellar disease Neurological 0.844 0.661 – 1.08 0.171 79 790 all phecode
334.2 Anterior horn cell disease Neurological 0.944 0.77 – 1.16 0.578 110 1080 all phecode
334.21 Amyotrophic Lateral Sclerosis Neurological 0.819 0.635 – 1.06 0.123 71 693 all phecode
335 Multiple sclerosis Neurological 0.943 0.847 – 1.05 0.29 396 3951 all phecode
337 Disorders of the autonomic nervous system Neurological 1.07 0.99 – 1.15 0.0901 808 7413 all phecode
337.1 Peripheral autonomic neuropathy Neurological 1.06 0.945 – 1.18 0.337 370 3164 all phecode
338 Pain Neurological 1.03 1.01 – 1.05 0.00198 20346 26417 all phecode
338.1 Acute pain Neurological 1.03 1 – 1.05 0.0168 15582 26313 all phecode
338.2 Chronic pain Neurological 1.05 1.02 – 1.07 0.000136 10994 26368 all phecode
339 Other headache syndromes Neurological 1.04 1.01 – 1.06 0.00617 9242 34658 all phecode
340 Migraine Neurological 1.06 1.03 – 1.09 3.42e-05 6708 30587 all phecode
340.1 Migrain with aura Neurological 1.07 1.03 – 1.11 0.000461 3624 23684 all phecode
341
Other demyelinating diseases of central nervous
Other demyelinating diseases of central nervous system
 Neurological 0.877 0.729 – 1.06 0.166 133 1330 all phecode
342 Hemiplegia Neurological 0.949 0.859 – 1.05 0.308 464 4607 all phecode
343 Infantile cerebral palsy Neurological 0.988 0.788 – 1.24 0.915 85 847 all phecode
344 Other paralytic syndromes Neurological 0.948 0.873 – 1.03 0.206 682 6808 all phecode
345 Epilepsy, recurrent seizures, convulsions Neurological 1.05 1 – 1.09 0.032 2553 25307 all phecode
345.1 Epilepsy Neurological 1.04 0.964 – 1.13 0.296 747 7465 all phecode
345.11 Generalized convulsive epilepsy Neurological 1.05 0.909 – 1.2 0.528 233 2330 all phecode
345.12 Partial epilepsy Neurological 1.06 0.963 – 1.16 0.246 534 5335 all phecode
345.3 Convulsions Neurological 1.04 1 – 1.09 0.0521 2396 23796 all phecode
346
Abnormal findings on study of brain and/or
Abnormal findings on study of brain and/or nervous system
 Neurological 1.05 0.896 – 1.24 0.534 183 1824 all phecode
346.1
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of skull and head
 Neurological 1.05 0.99 – 1.11 0.105 1472 14587 all phecode
346.2
Nonspecific abnormal results of function study
Nonspecific abnormal results of function study of brain and central nervous system
 Neurological 1.02 0.84 – 1.24 0.834 120 1181 all phecode
346.3
Nonspecific abnormal findings in cerebrospinal
Nonspecific abnormal findings in cerebrospinal fluid
 Neurological 0.961 0.781 – 1.18 0.709 110 1100 all phecode
347 Cataplexy and narcolepsy Neurological 0.967 0.786 – 1.19 0.75 101 1010 all phecode
348 Other conditions of brain Neurological 1.04 0.986 – 1.09 0.161 1793 17894 all phecode
348.2 Cerebral edema and compression of brain Neurological 1.03 0.961 – 1.11 0.379 905 9034 all phecode
348.4 Cerebral cysts Neurological 0.94 0.813 – 1.09 0.408 229 2290 all phecode
348.7 Coma Neurological 1.11 0.963 – 1.27 0.151 229 2275 all phecode
348.8 Encephalopathy, not elsewhere classified Neurological 1.06 0.985 – 1.14 0.119 853 8479 all phecode
348.9 Other conditions of brain, NOS Neurological 1.03 0.983 – 1.07 0.224 2341 23287 all phecode
349
Other and unspecified disorders of the nervous
Other and unspecified disorders of the nervous system
 Neurological 1.07 0.997 – 1.15 0.0616 941 9385 all phecode
350 Abnormal movement Neurological 1.03 1 – 1.06 0.0324 6706 38762 all phecode
350.1 Abnormal involuntary movements Neurological 1.03 0.987 – 1.06 0.196 3273 30524 all phecode
350.2 Abnormality of gait Neurological 1.03 0.99 – 1.06 0.157 3920 30520 all phecode
350.3 Lack of coordination Neurological 1.02 0.957 – 1.09 0.505 1062 10554 all phecode
350.5 Abnormal reflex Neurological 1.09 0.938 – 1.27 0.258 200 1988 all phecode
350.6 Disturbances of sensation of smell and taste Neurological 0.963 0.878 – 1.06 0.426 558 5576 all phecode
351 Other peripheral nerve disorders Neurological 1.05 1.02 – 1.08 0.000238 7401 34460 all phecode
352 Disorders of other cranial nerves Neurological 1.01 0.96 – 1.07 0.679 1714 17106 all phecode
352.1 Trigeminal nerve disorders [CN5] Neurological 1.01 0.923 – 1.11 0.788 535 5344 all phecode
352.2 Facial nerve disorders [CN7] Neurological 1 0.927 – 1.08 0.976 783 7826 all phecode
353 Nerve root and plexus disorders Neurological 1.05 1.02 – 1.09 0.00239 4256 33369 all phecode
353.1 Nerve plexus lesions Neurological 1.06 0.951 – 1.18 0.291 390 3900 all phecode
353.2 Nerve root lesions Neurological 1.16 0.963 – 1.39 0.12 130 1287 all phecode
355 Complex regional/central pain syndrome Neurological 1.08 0.984 – 1.19 0.105 531 5295 all phecode
355.1 Chronic pain syndrome Neurological 1.05 0.977 – 1.13 0.176 843 8386 all phecode
356 Hereditary and idiopathic peripheral neuropathy Neurological 1.06 1.02 – 1.11 0.00692 2335 20731 all phecode
357 Inflammatory and toxic neuropathy Neurological 1.09 1.05 – 1.13 1.71e-05 3472 29956 all phecode
358 Myoneural disorders Neurological 1.07 1 – 1.14 0.0445 1147 11391 all phecode
358.1 Myasthenia gravis Neurological 1.04 0.839 – 1.28 0.741 109 1082 all phecode
359 Muscular dystrophies and other myopathies Neurological 0.977 0.916 – 1.04 0.468 1134 11274 all phecode
359.1 Muscular dystrophies Neurological 0.851 0.653 – 1.11 0.233 64 632 all phecode
359.2 Myopathy Neurological 0.975 0.913 – 1.04 0.452 1092 10843 all phecode
360 Disorders of the globe Sense Organs 1.2 0.989 – 1.45 0.0651 131 1276 all phecode
360.2 Progressive myopia Sense Organs 1.1 0.841 – 1.44 0.486 65 640 all phecode
361 Retinal detachments and defects Sense Organs 1 0.927 – 1.09 0.916 733 7131 all phecode
361.1 Retinal detachment with retinal defect Sense Organs 1 0.887 – 1.14 0.948 302 2962 all phecode
362 Other retinal disorders Sense Organs 1.02 0.983 – 1.06 0.286 3569 22997 all phecode
362.2
Degeneration of macula and posterior pole of
Degeneration of macula and posterior pole of retina
 Sense Organs 1 0.957 – 1.05 0.86 2172 15483 all phecode
362.21 Macular degeneration, dry Sense Organs 0.927 0.831 – 1.03 0.169 419 3438 all phecode
362.22 Macular degeneration, wet Sense Organs 0.904 0.758 – 1.08 0.266 148 1184 all phecode
362.23 Cystoid macular degeneration of retina Sense Organs 1.01 0.904 – 1.12 0.888 408 3839 all phecode
362.26 Macular puckering of retina Sense Organs 0.972 0.906 – 1.04 0.425 976 8610 all phecode
362.27 Drusen (degenerative) of retina Sense Organs 0.961 0.872 – 1.06 0.418 488 4558 all phecode
362.29 Macular degeneration (senile) of retina NOS Sense Organs 1.02 0.964 – 1.07 0.567 1883 13955 all phecode
362.3 Other nondiabetic retinopathy Sense Organs 1.07 1 – 1.15 0.0504 976 8527 all phecode
362.31 Separation of retinal layers Sense Organs 1.09 0.98 – 1.21 0.113 413 4056 all phecode
362.4 Retinal vascular changes and abnomalities Sense Organs 0.954 0.877 – 1.04 0.272 662 5933 all phecode
362.6 Peripheral retinal degenerations Sense Organs 1 0.899 – 1.12 0.953 392 3787 all phecode
362.7 Hereditary retinal dystrophies Sense Organs 0.984 0.85 – 1.14 0.831 215 2103 all phecode
362.8 Retinal hemorrhage/ischemia Sense Organs 1.01 0.883 – 1.16 0.842 241 2368 all phecode
362.9 Retinal edema Sense Organs 0.99 0.877 – 1.12 0.864 324 2936 all phecode
363
Chorioretinal inflammations, scars, and other
Chorioretinal inflammations, scars, and other disorders of choroid
 Sense Organs 1.04 0.939 – 1.14 0.487 492 4746 all phecode
363.3 Chorioretinal scars Sense Organs 1.02 0.906 – 1.15 0.722 332 3184 all phecode
364 Corneal opacity and other disorders of cornea Sense Organs 1.01 0.944 – 1.07 0.852 1132 10772 all phecode
364.1 Corneal opacity Sense Organs 0.951 0.852 – 1.06 0.363 394 3846 all phecode
364.2 Corneal edema Sense Organs 1.03 0.855 – 1.25 0.735 123 1208 all phecode
364.4 Corneal degenerations Sense Organs 1.07 0.96 – 1.19 0.223 402 3962 all phecode
364.41 Keratoconus Sense Organs 1.02 0.802 – 1.31 0.851 75 739 all phecode
364.5 Corneal dystrophy Sense Organs 0.966 0.878 – 1.06 0.476 502 4682 all phecode
364.51 Fuchs' dystrophy Sense Organs 0.99 0.868 – 1.13 0.88 266 2521 all phecode
364.9 Cornea replaced by transplant Sense Organs 1.09 0.871 – 1.37 0.446 91 885 all phecode
365 Glaucoma Sense Organs 1.02 0.975 – 1.06 0.423 2672 21326 all phecode
365.1 Open-angle glaucoma Sense Organs 0.938 0.864 – 1.02 0.13 705 6491 all phecode
365.11 Primary open angle glaucoma Sense Organs 0.965 0.865 – 1.08 0.521 403 3681 all phecode
365.2 Primary angle-closure glaucoma Sense Organs 0.987 0.86 – 1.13 0.846 251 2370 all phecode
366 Cataract Sense Organs 1.03 0.999 – 1.05 0.0623 8611 28043 all phecode
366.1 Nonsenile Cataract Sense Organs 0.989 0.851 – 1.15 0.885 207 1979 all phecode
366.2 Senile cataract Sense Organs 1.03 0.996 – 1.06 0.0814 5480 24980 all phecode
367
Disorders of refraction and accommodation
Disorders of refraction and accommodation; blindness and low vision
 Sense Organs 1.01 0.984 – 1.03 0.471 8967 37779 all phecode
367.1 Myopia Sense Organs 1.01 0.983 – 1.05 0.362 5014 34677 all phecode
367.2 Astigmatism Sense Organs 0.991 0.958 – 1.03 0.607 4161 32463 all phecode
367.8 Hypermetropia Sense Organs 0.966 0.921 – 1.01 0.162 2039 18599 all phecode
367.9 Blindness and low vision Sense Organs 1.04 0.982 – 1.11 0.171 1277 12356 all phecode
368 Visual disturbances Sense Organs 1.01 0.985 – 1.04 0.342 5715 39599 all phecode
368.1 Amblyopia Sense Organs 1.05 0.962 – 1.14 0.289 651 6479 all phecode
368.2 Diplopia and disorders of binocular vision Sense Organs 1.02 0.951 – 1.08 0.644 1087 10786 all phecode
368.3 Anisometropia Sense Organs 0.946 0.819 – 1.09 0.447 219 2168 all phecode
368.4 Visual field defects Sense Organs 1.02 0.957 – 1.09 0.528 1132 11173 all phecode
368.9 Subjective visual disturbances Sense Organs 0.98 0.917 – 1.05 0.56 1070 10620 all phecode
368.91 Psychophysical visual disturbances Sense Organs 0.977 0.801 – 1.19 0.821 120 1171 all phecode
369 Infection of the eye Sense Organs 1.02 0.984 – 1.06 0.26 3185 28240 all phecode
369.2 Eye infection, viral Sense Organs 0.995 0.905 – 1.09 0.921 502 4954 all phecode
369.5 Conjunctivitis, infectious Sense Organs 1.02 0.979 – 1.06 0.339 2716 24970 all phecode
370 Keratitis Sense Organs 0.938 0.884 – 0.995 0.0332 1365 13169 all phecode
370.1 Corneal ulcer Sense Organs 0.901 0.778 – 1.04 0.166 223 2194 all phecode
370.2 Superficial keratitis Sense Organs 0.928 0.846 – 1.02 0.115 546 5393 all phecode
370.3 Keratoconjunctivitis Sense Organs 0.973 0.893 – 1.06 0.532 649 6263 all phecode
370.31 Keratoconjunctivitis sicca Sense Organs 0.95 0.807 – 1.12 0.541 179 1677 all phecode
371 Inflammation of the eye Sense Organs 1.01 0.981 – 1.05 0.394 4414 32310 all phecode
371.1 Uveitis, noninfectious or NOS Sense Organs 0.989 0.9 – 1.09 0.819 541 5278 all phecode
371.2 Conjunctivitis, noninfectious Sense Organs 0.952 0.886 – 1.02 0.186 906 8939 all phecode
371.21 Allergic conjunctivitis Sense Organs 0.949 0.877 – 1.03 0.189 756 7515 all phecode
371.3 Inflammation of eyelids Sense Organs 1.02 0.986 – 1.06 0.222 3398 26983 all phecode
371.33 Noninfectious dermatoses of eyelid Sense Organs 1.01 0.843 – 1.21 0.916 133 1291 all phecode
372 Disorders of conjunctiva Sense Organs 0.987 0.925 – 1.05 0.69 1118 10728 all phecode
374 Other disorders of eyelids Sense Organs 1.01 0.974 – 1.06 0.504 2940 24188 all phecode
374.1 Ectropion or entropion Sense Organs 0.944 0.849 – 1.05 0.291 431 4084 all phecode
374.2 Lagophthalmos Sense Organs 1.01 0.874 – 1.16 0.918 235 2335 all phecode
374.3 Ptosis of eyelid Sense Organs 0.988 0.926 – 1.06 0.727 1102 10734 all phecode
374.6 Dermatochalasis Sense Organs 1.01 0.941 – 1.08 0.853 1040 9720 all phecode
375 Disorders of lacrimal system Sense Organs 0.976 0.941 – 1.01 0.196 3694 26045 all phecode
375.1 Dry eyes Sense Organs 0.987 0.952 – 1.02 0.464 4040 26751 all phecode
375.2 Epiphora Sense Organs 0.979 0.883 – 1.09 0.686 442 4354 all phecode
376 Disorders of the orbit Sense Organs 0.97 0.864 – 1.09 0.613 352 3508 all phecode
377 Disorders of optic nerve and visual pathways Sense Organs 0.991 0.922 – 1.06 0.795 913 9021 all phecode
377.1 Optic atrophy Sense Organs 1.01 0.884 – 1.14 0.931 283 2793 all phecode
377.3 Optic neuritis/neuropathy Sense Organs 0.956 0.873 – 1.05 0.327 585 5775 all phecode
378
Strabismus and other disorders of binocular eye
Strabismus and other disorders of binocular eye movements
 Sense Organs 0.986 0.928 – 1.05 0.653 1275 12460 all phecode
378.1 Strabismus (not specified as paralytic) Sense Organs 0.967 0.898 – 1.04 0.384 828 8130 all phecode
378.2 Nystagmus and other irregular eye movements Sense Organs 0.974 0.823 – 1.15 0.756 170 1686 all phecode
378.5 Paralytic strabismus Sense Organs 0.976 0.871 – 1.09 0.68 349 3437 all phecode
379 Other disorders of eye Sense Organs 1 0.973 – 1.04 0.785 5046 29999 all phecode
379.1 Scleritis and episcleritis Sense Organs 1.11 0.939 – 1.3 0.228 176 1743 all phecode
379.2 Disorders of vitreous body Sense Organs 0.981 0.945 – 1.02 0.318 3634 23186 all phecode
379.3 Aphakia and other disorders of lens Sense Organs 1.04 0.866 – 1.25 0.667 135 1258 all phecode
379.4 Anomalies of pupillary function Sense Organs 0.982 0.864 – 1.12 0.781 287 2833 all phecode
379.5 Disorders of iris and ciliary body Sense Organs 1.07 0.945 – 1.21 0.294 304 2948 all phecode
379.51 Pigmentary iris degeneration Sense Organs 1.05 0.824 – 1.33 0.713 77 731 all phecode
379.9 Pain, swelling or discharge of eye Sense Organs 0.967 0.907 – 1.03 0.311 1129 11130 all phecode
380 Disorders of external ear Sense Organs 0.984 0.94 – 1.03 0.486 2242 20393 all phecode
380.1 Otitis externa Sense Organs 1.08 1.03 – 1.15 0.00482 1469 14580 all phecode
380.4 Impacted cerumen Sense Organs 0.981 0.941 – 1.02 0.378 2648 23557 all phecode
381 Otitis media and Eustachian tube disorders Sense Organs 1.03 1 – 1.07 0.0446 4255 36417 all phecode
381.1 Otitis media Sense Organs 1.06 1.02 – 1.1 0.00484 3079 29813 all phecode
381.11 Suppurative and unspecified otitis media Sense Organs 1.05 1.01 – 1.1 0.0243 2610 25602 all phecode
381.2 Eustachian tube disorders Sense Organs 1 0.955 – 1.06 0.866 1816 17827 all phecode
381.3 Mastoiditis & related conditions Sense Organs 1.09 0.919 – 1.3 0.317 153 1530 all phecode
381.9 Otorrhea Sense Organs 1.13 1.01 – 1.27 0.0293 372 3713 all phecode
382 Otalgia Sense Organs 1.01 0.962 – 1.06 0.652 1884 18673 all phecode
383 Otosclerosis Sense Organs 1.07 0.879 – 1.3 0.506 124 1240 all phecode
384 Other disorders of tympanic membrane Sense Organs 1.09 0.988 – 1.19 0.0885 516 5156 all phecode
384.1 Myringitis Sense Organs 0.909 0.665 – 1.24 0.546 51 502 all phecode
384.4 Perforation of tympanic membrane Sense Organs 1.04 0.933 – 1.16 0.486 403 4029 all phecode
385 Other disorders of middle ear and mastoid Sense Organs 0.957 0.863 – 1.06 0.41 432 4320 all phecode
385.3 Cholesteatoma Sense Organs 0.972 0.853 – 1.11 0.668 277 2770 all phecode
385.5
Tympanosclerosis and middle ear disease related
Tympanosclerosis and middle ear disease related to otitis media
 Sense Organs 1.05 0.87 – 1.28 0.586 118 1180 all phecode
386
Vertiginous syndromes and other disorders of
Vertiginous syndromes and other disorders of vestibular system
 Sense Organs 1.06 1.01 – 1.12 0.015 1882 18186 all phecode
386.1 Meniere's disease Sense Organs 0.926 0.821 – 1.04 0.213 319 3156 all phecode
386.2 Peripheral or central vertigo Sense Organs 1.06 1.01 – 1.12 0.03 1586 15423 all phecode
386.21 Central origin vertigo Sense Organs 1.06 0.993 – 1.12 0.0825 1208 11844 all phecode
386.3 Labyrinthitis Sense Organs 1.05 0.995 – 1.11 0.0768 1482 14530 all phecode
386.9
Dizziness and giddiness (Light-headedness and
Dizziness and giddiness (Light-headedness and vertigo)
 Sense Organs 1.05 1.02 – 1.08 0.000425 6933 38286 all phecode
388 Other disorders of ear Sense Organs 1.01 0.941 – 1.08 0.811 960 9501 all phecode
389 Hearing loss Sense Organs 1 0.978 – 1.03 0.781 8182 38069 all phecode
389.1 Sensorineural hearing loss Sense Organs 0.976 0.943 – 1.01 0.178 4107 29258 all phecode
389.2 Conductive hearing loss Sense Organs 0.962 0.895 – 1.03 0.286 905 9042 all phecode
389.3 Degenerative and vascular disorders of ear Sense Organs 0.866 0.74 – 1.01 0.0741 192 1808 all phecode
389.4 Tinnitus Sense Organs 0.994 0.949 – 1.04 0.783 2291 22130 all phecode
389.5 Disorders of acoustic nerve Sense Organs 1.08 0.895 – 1.31 0.413 124 1229 all phecode
394 Rheumatic disease of the heart valves Circulatory System 1.02 0.968 – 1.08 0.396 1458 13732 all phecode
394.1 Mitral valve stenosis and aortic valve stenosis Circulatory System 1.05 0.933 – 1.18 0.43 350 3415 all phecode
394.2 Mitral valve disease Circulatory System 0.977 0.884 – 1.08 0.648 462 4560 all phecode
394.3 Aortic valve disease Circulatory System 1.03 0.875 – 1.2 0.751 176 1691 all phecode
394.4 Acute rheumatic heart disease Circulatory System 0.927 0.695 – 1.24 0.608 55 546 all phecode
394.7 Disease of tricuspid valve Circulatory System 1 0.917 – 1.1 0.961 587 5739 all phecode
395 Heart valve disorders Circulatory System 1.01 0.97 – 1.04 0.777 3976 28748 all phecode
395.1 Nonrheumatic mitral valve disorders Circulatory System 0.983 0.938 – 1.03 0.461 2175 20441 all phecode
395.2 Nonrheumatic aortic valve disorders Circulatory System 1.05 0.997 – 1.1 0.0687 2060 17194 all phecode
395.3 Nonrheumatic tricuspid valve disorders Circulatory System 0.973 0.883 – 1.07 0.581 493 4864 all phecode
395.4 Nonrheumatic pulmonary valve disorders Circulatory System 0.914 0.742 – 1.13 0.397 108 1080 all phecode
395.6 Heart valve replaced Circulatory System 1.03 0.965 – 1.09 0.398 1177 10833 all phecode
396 Abnormal heart sounds Circulatory System 1.02 0.984 – 1.05 0.339 4718 34395 all phecode
401 Hypertension Circulatory System 1.14 1.11 – 1.16 1.8e-31 23317 23367 all phecode
401.1 Essential hypertension Circulatory System 1.14 1.11 – 1.16 2.05e-31 23158 23364 all phecode
401.2 Hypertensive heart and/or renal disease Circulatory System 1.15 1.1 – 1.2 6.24e-11 3503 14616 all phecode
401.21 Hypertensive heart disease Circulatory System 1.13 1.05 – 1.22 0.00129 893 6607 all phecode
401.22 Hypertensive chronic kidney disease Circulatory System 1.15 1.1 – 1.21 5.19e-09 2584 13072 all phecode
401.3 Other hypertensive complications Circulatory System 1.13 1.08 – 1.18 1.48e-07 2679 15833 all phecode
411 Ischemic Heart Disease Circulatory System 1.14 1.11 – 1.17 3.24e-22 8807 30299 all phecode
411.1 Unstable angina (intermediate coronary syndrome) Circulatory System 1.23 1.15 – 1.32 6.74e-09 937 8574 all phecode
411.2 Myocardial infarction Circulatory System 1.2 1.15 – 1.24 2.05e-20 3594 21716 all phecode
411.3 Angina pectoris Circulatory System 1.17 1.11 – 1.22 1.62e-11 2485 18304 all phecode
411.4 Coronary atherosclerosis Circulatory System 1.15 1.12 – 1.19 1.37e-22 7555 27492 all phecode
411.41 Aneurysm and dissection of heart Circulatory System 1.01 0.852 – 1.21 0.877 156 1529 all phecode
411.8
Other chronic ischemic heart disease
Other chronic ischemic heart disease, unspecified
 Circulatory System 1.17 1.14 – 1.21 5.17e-25 6331 25741 all phecode
411.9
Other acute and subacute forms of ischemic
Other acute and subacute forms of ischemic heart disease
 Circulatory System 1.09 0.988 – 1.21 0.0841 442 4211 all phecode
414 Other forms of chronic heart disease Circulatory System 1.1 1.06 – 1.15 2.39e-06 3101 22616 all phecode
414.2 ASCVD Circulatory System 1.09 1.01 – 1.19 0.0298 718 6816 all phecode
415 Pulmonary heart disease Circulatory System 1.03 0.989 – 1.07 0.167 3366 30208 all phecode
415.1 Acute pulmonary heart disease Circulatory System 1.03 0.98 – 1.08 0.25 1912 19014 all phecode
415.11 Pulmonary embolism and infarction, acute Circulatory System 1.03 0.983 – 1.09 0.197 1906 18953 all phecode
415.2 Chronic pulmonary heart disease Circulatory System 1.05 0.995 – 1.1 0.0762 1808 17605 all phecode
415.21 Primary pulmonary hypertension Circulatory System 1.07 0.987 – 1.16 0.101 706 7032 all phecode
416 Cardiomegaly Circulatory System 1.03 0.971 – 1.1 0.313 1254 12372 all phecode
418 Nonspecific chest pain Circulatory System 1.06 1.04 – 1.08 9.05e-08 12650 33952 all phecode
418.1 Precordial pain Circulatory System 1.05 0.988 – 1.11 0.126 1471 13782 all phecode
420 Carditis Circulatory System 1 0.951 – 1.06 0.883 1588 15680 all phecode
420.1 Myocarditis Circulatory System 0.995 0.802 – 1.23 0.96 97 958 all phecode
420.2 Pericarditis Circulatory System 0.993 0.923 – 1.07 0.86 842 8402 all phecode
420.21 Acute pericarditis Circulatory System 0.967 0.821 – 1.14 0.685 177 1764 all phecode
420.22 Chronic pericarditis Circulatory System 0.963 0.794 – 1.17 0.7 117 1153 all phecode
420.3 Endocarditis Circulatory System 1.02 0.945 – 1.11 0.584 764 7535 all phecode
425 Cardiomyopathy Circulatory System 1.06 1.01 – 1.11 0.0137 2078 19881 all phecode
425.1 Primary/intrinsic cardiomyopathies Circulatory System 1.06 1.01 – 1.12 0.0141 1989 19025 all phecode
425.11 Hypertrophic obstructive cardiomyopathy Circulatory System 1.05 0.91 – 1.22 0.488 208 2050 all phecode
425.12 Other hypertrophic cardiomyopathy Circulatory System 1.03 0.888 – 1.19 0.721 201 1992 all phecode
425.2 Secondary/extrinsic cardiomyopathies Circulatory System 0.966 0.857 – 1.09 0.576 317 3170 all phecode
425.8 Other cardiomyopathy Circulatory System 1.06 0.844 – 1.33 0.628 95 931 all phecode
426 Cardiac conduction disorders Circulatory System 1.04 1.02 – 1.07 0.00078 12327 25440 all phecode
426.2 Atrioventricular [AV] block Circulatory System 1.01 0.955 – 1.06 0.808 1903 11501 all phecode
426.21 First degree AV block Circulatory System 0.984 0.924 – 1.05 0.599 1313 8899 all phecode
426.22 Mobitz II AV block Circulatory System 0.978 0.745 – 1.28 0.871 64 553 all phecode
426.23 Second degree AV block Circulatory System 0.998 0.862 – 1.16 0.978 216 1925 all phecode
426.24 Atrioventricular block, complete Circulatory System 0.999 0.902 – 1.11 0.987 461 3823 all phecode
426.25 Other heart block Circulatory System 1.12 0.957 – 1.3 0.163 203 1803 all phecode
426.3 Bundle branch block Circulatory System 1.02 0.971 – 1.07 0.449 2306 13999 all phecode
426.31 Right bundle branch block Circulatory System 1.01 0.953 – 1.07 0.718 1423 10758 all phecode
426.32 Left bundle branch block Circulatory System 1.01 0.939 – 1.08 0.843 969 8110 all phecode
426.4 Anomalous atrioventricular excitation Circulatory System 0.783 0.617 – 0.993 0.044 82 820 all phecode
426.7 Abnormal electrocardiogram [ECG] [EKG] Circulatory System 1.05 1.02 – 1.07 0.000502 10577 25186 all phecode
426.8 Other cardiac conduction disorders Circulatory System 1.1 1.01 – 1.2 0.0213 679 6650 all phecode
426.9 Cardiac pacemaker/device in situ Circulatory System 1.06 1.01 – 1.12 0.0225 1754 11536 all phecode
426.91 Cardiac pacemaker in situ Circulatory System 1.02 0.953 – 1.09 0.598 1171 8184 all phecode
426.92 Cardiac defibrillator in situ Circulatory System 1.12 1.04 – 1.2 0.00343 846 7320 all phecode
427 Cardiac dysrhythmias Circulatory System 1.02 1 – 1.04 0.0496 17397 25735 all phecode
427.1 Paroxysmal tachycardia, unspecified Circulatory System 1.02 0.974 – 1.06 0.434 2474 18178 all phecode
427.11 Paroxysmal supraventricular tachycardia Circulatory System 1.02 0.962 – 1.07 0.563 1595 14293 all phecode
427.12 Paroxysmal ventricular tachycardia Circulatory System 1.02 0.959 – 1.09 0.51 1181 9915 all phecode
427.2 Atrial fibrillation and flutter Circulatory System 1.01 0.972 – 1.04 0.754 5313 18688 all phecode
427.21 Atrial fibrillation Circulatory System 1 0.969 – 1.04 0.846 5188 18409 all phecode
427.22 Atrial flutter Circulatory System 0.961 0.91 – 1.02 0.155 1693 11042 all phecode
427.3 Other specified cardiac dysrhythmias Circulatory System 1.03 1 – 1.06 0.0395 8688 25552 all phecode
427.4 Cardiac arrest and ventricular fibrillation Circulatory System 0.993 0.905 – 1.09 0.882 536 5233 all phecode
427.41 Ventricular fibrillation and flutter Circulatory System 0.949 0.82 – 1.1 0.487 216 2118 all phecode
427.42 Cardiac arrest Circulatory System 1.01 0.909 – 1.12 0.841 410 4034 all phecode
427.5 Arrhythmia (cardiac) NOS Circulatory System 1.01 0.98 – 1.04 0.57 6905 25457 all phecode
427.6 Premature beats Circulatory System 1.03 0.983 – 1.08 0.224 2359 16248 all phecode
427.61 Supraventricular premature beats Circulatory System 1.01 0.929 – 1.1 0.802 670 6287 all phecode
427.7 Tachycardia NOS Circulatory System 1.07 1.04 – 1.1 3.34e-05 5124 25531 all phecode
427.8 Sinoatrial node dysfunction (Bradycardia) Circulatory System 1.01 0.939 – 1.09 0.789 912 7501 all phecode
427.9 Palpitations Circulatory System 0.983 0.95 – 1.02 0.331 4430 24505 all phecode
428 Congestive heart failure; nonhypertensive Circulatory System 1.1 1.06 – 1.14 1.84e-07 4300 23663 all phecode
428.1 Congestive heart failure (CHF) NOS Circulatory System 1.09 1.05 – 1.13 2.41e-06 3756 22446 all phecode
428.2 Heart failure NOS Circulatory System 1.11 1.07 – 1.16 1.97e-08 3701 21722 all phecode
428.3
Heart failure with reduced EF [Systolic or
Heart failure with reduced EF [Systolic or combined heart failure]
 Circulatory System 1.12 1.07 – 1.18 1.23e-05 1765 14476 all phecode
428.4
Heart failure with preserved EF [Diastolic
Heart failure with preserved EF [Diastolic heart failure]
 Circulatory System 1.08 1.02 – 1.14 0.00591 1648 13395 all phecode
429
Ill-defined descriptions and complications of
Ill-defined descriptions and complications of heart disease
 Circulatory System 1.05 1.02 – 1.07 4.76e-05 12635 32504 all phecode
429.1 Heart transplant/surgery Circulatory System 1.06 0.992 – 1.12 0.0875 1219 11696 all phecode
429.2 Abnormal function study of cardiovascular system Circulatory System 1.08 1.04 – 1.11 1.24e-06 6322 29232 all phecode
429.3 Symptoms involving cardiovascular system Circulatory System 1.05 1.02 – 1.07 0.000329 9650 32421 all phecode
429.9 Cardiac complications, not elsewhere classified Circulatory System 1.01 0.929 – 1.09 0.869 723 7072 all phecode
430 Intracranial hemorrhage Circulatory System 1.07 0.986 – 1.15 0.108 789 7842 all phecode
430.1 Subarachnoid hemorrhage Circulatory System 1.17 1.02 – 1.33 0.0219 261 2610 all phecode
430.2 Intracerebral hemorrhage Circulatory System 0.992 0.886 – 1.11 0.894 368 3671 all phecode
430.3 Subdural hemorrhage Circulatory System 1.01 0.884 – 1.15 0.919 272 2680 all phecode
433 Cerebrovascular disease Circulatory System 1.08 1.05 – 1.11 1.22e-06 5463 32242 all phecode
433.1 Occlusion and stenosis of precerebral arteries Circulatory System 1.16 1.11 – 1.22 1.94e-09 1978 16212 all phecode
433.11
Occlusion of cerebral arteries, with cerebral
Occlusion of cerebral arteries, with cerebral infarction
 Circulatory System 1.24 1.09 – 1.41 0.00135 260 2517 all phecode
433.12 Cerebral atherosclerosis Circulatory System 1.33 1.04 – 1.7 0.0212 80 789 all phecode
433.2 Occlusion of cerebral arteries Circulatory System 1.07 1.02 – 1.12 0.00281 2437 21732 all phecode
433.21
Cerebral artery occlusion, with cerebral
Cerebral artery occlusion, with cerebral infarction
 Circulatory System 1.07 1.02 – 1.12 0.00335 2357 21103 all phecode
433.3 Cerebral ischemia Circulatory System 1.06 1.01 – 1.1 0.00953 2780 22868 all phecode
433.31 Transient cerebral ischemia Circulatory System 1.05 1 – 1.1 0.0333 2409 20762 all phecode
433.5 Cerebral aneurysm Circulatory System 1.09 0.989 – 1.21 0.0803 474 4724 all phecode
433.6 Acute, but ill-defined cerebrovascular disease Circulatory System 1.11 1 – 1.23 0.0469 464 4518 all phecode
433.8 Late effects of cerebrovascular disease Circulatory System 1.05 0.966 – 1.14 0.254 695 6822 all phecode
440 Atherosclerosis Circulatory System 1.13 1.08 – 1.18 4.27e-08 2477 19724 all phecode
440.1 Atherosclerosis of renal artery Circulatory System 1.29 1.12 – 1.49 0.00049 231 2291 all phecode
440.2 Atherosclerosis of the extremities Circulatory System 1.13 1.07 – 1.2 1.75e-05 1516 13532 all phecode
440.21
Atherosclerosis of native arteries of the
Atherosclerosis of native arteries of the extremities with ulceration or gangrene
 Circulatory System 1.06 0.934 – 1.21 0.357 274 2669 all phecode
440.22
Atherosclerosis of native arteries of the
Atherosclerosis of native arteries of the extremities with intermittent claudication
 Circulatory System 1.12 1.04 – 1.19 0.00138 1040 9647 all phecode
440.9 Atherosclerosis of aorta Circulatory System 1.13 1.04 – 1.21 0.002 846 8124 all phecode
441 Vascular insufficiency of intestine Circulatory System 1.1 1 – 1.21 0.0443 515 5115 all phecode
441.1 Acute vascular insufficiency of intestine Circulatory System 1.21 1.05 – 1.39 0.00655 240 2387 all phecode
441.2 Chronic vascular insufficiency of intestine Circulatory System 1.18 0.992 – 1.4 0.0622 154 1536 all phecode
442 Other aneurysm Circulatory System 1.1 1.06 – 1.15 3.47e-06 2779 21466 all phecode
442.1 Aortic aneurysm Circulatory System 1.11 1.06 – 1.16 3.2e-05 2054 16492 all phecode
442.11 Abdominal aortic aneurysm Circulatory System 1.15 1.08 – 1.23 1.47e-05 1189 10558 all phecode
442.2 Aneurysm of iliac artery Circulatory System 1.18 1.01 – 1.37 0.039 202 2002 all phecode
442.3 Aneurysm of artery of lower extremity Circulatory System 1.28 1.09 – 1.51 0.00245 179 1765 all phecode
442.4 Arterial dissection Circulatory System 0.949 0.811 – 1.11 0.511 184 1840 all phecode
442.8 Aneurysm of other specified artery Circulatory System 1.05 0.943 – 1.17 0.373 399 3978 all phecode
443 Peripheral vascular disease Circulatory System 1.07 1.03 – 1.12 0.000426 3086 24814 all phecode
443.1 Raynaud's syndrome Circulatory System 0.871 0.805 – 0.943 0.000606 742 7390 all phecode
443.7
Peripheral angiopathy in diseases classified
Peripheral angiopathy in diseases classified elsewhere
 Circulatory System 1.04 0.904 – 1.2 0.569 220 2087 all phecode
443.8 Other specified peripheral vascular diseases Circulatory System 1.08 1.03 – 1.13 0.000575 2557 21985 all phecode
443.9 Peripheral vascular disease, unspecified Circulatory System 1.14 1.09 – 1.19 4.03e-08 2341 18862 all phecode
444 Arterial embolism and thrombosis Circulatory System 1.08 1.01 – 1.17 0.0339 848 8423 all phecode
444.1
Arterial embolism and thrombosis of lower
Arterial embolism and thrombosis of lower extremity artery
 Circulatory System 1.13 0.996 – 1.27 0.0581 313 3099 all phecode
444.2 Embolism and thrombosis of abdominal aorta Circulatory System 1.14 0.957 – 1.36 0.14 155 1548 all phecode
446 Polyarteritis nodosa and allied conditions Circulatory System 1.04 0.941 – 1.15 0.429 460 4559 all phecode
446.4 Wegener's granulomatosis Circulatory System 0.951 0.775 – 1.17 0.63 109 1075 all phecode
446.5 Giant cell arteritis Circulatory System 0.926 0.725 – 1.18 0.535 79 749 all phecode
446.9 Arteritis NOS Circulatory System 1.03 0.906 – 1.17 0.647 289 2876 all phecode
447 Other disorders of arteries and arterioles Circulatory System 1.09 1.04 – 1.13 0.00015 2647 22765 all phecode
447.1 Stricture of artery Circulatory System 1.2 1.1 – 1.32 0.000101 523 5163 all phecode
447.7 Aortic ectasia Circulatory System 1.01 0.937 – 1.09 0.77 804 7938 all phecode
448 Disease of capillaries Circulatory System 0.928 0.873 – 0.987 0.0175 1237 12127 all phecode
450 Noninfectious disorders of lymphatic channels Circulatory System 0.953 0.909 – 0.999 0.0463 2104 20985 all phecode
451 Phlebitis and thrombophlebitis Circulatory System 0.977 0.902 – 1.06 0.576 738 7355 all phecode
451.2
Phlebitis and thrombophlebitis of lower
Phlebitis and thrombophlebitis of lower extremities
 Circulatory System 0.83 0.72 – 0.956 0.00996 244 2437 all phecode
452 Other venous embolism and thrombosis Circulatory System 1.01 0.974 – 1.04 0.727 4957 29867 all phecode
452.1 Iatrogenic pulmonary embolism and infarction Circulatory System 1 0.882 – 1.14 0.957 276 2747 all phecode
452.2 Deep vein thrombosis [DVT] Circulatory System 1 0.965 – 1.04 0.891 3260 26940 all phecode
452.8 Postphlebitic syndrome Circulatory System 0.88 0.739 – 1.05 0.155 154 1529 all phecode
453 Chronic venous hypertension Circulatory System 0.861 0.745 – 0.997 0.0448 220 2168 all phecode
454 Varicose veins Circulatory System 0.969 0.93 – 1.01 0.131 2827 24555 all phecode
454.1 Varicose veins of lower extremity Circulatory System 0.967 0.925 – 1.01 0.128 2469 21426 all phecode
454.11 Varicose veins of lower extremity, symptomtic Circulatory System 0.937 0.887 – 0.99 0.021 1565 15056 all phecode
455 Hemorrhoids Circulatory System 1.01 0.984 – 1.05 0.355 5799 29818 all phecode
456 Chronic venous insufficiency [CVI] Circulatory System 0.979 0.941 – 1.02 0.289 3097 24898 all phecode
457
Encounter for long-term (current) use of
Encounter for long-term (current) use of anticoagulants, antithrombotics, aspirin
 Circulatory System 1.11 1.06 – 1.16 2.57e-05 2095 15309 all phecode
457.2
Encounter for long-term (current) use of
Encounter for long-term (current) use of antiplatelets/antithrombotics
 Circulatory System 1.23 1.1 – 1.39 0.000467 324 3221 all phecode
457.3 Encounter for long-term (current) use of aspirin Circulatory System 1.09 1.04 – 1.15 0.000383 1973 14689 all phecode
458 Hypotension Circulatory System 1.06 1.03 – 1.09 0.000456 5091 32185 all phecode
458.1 Orthostatic hypotension Circulatory System 1.03 0.975 – 1.1 0.266 1344 12938 all phecode
458.2 Iatrogenic hypotension Circulatory System 1.07 1.01 – 1.14 0.0325 1109 11012 all phecode
458.9 Hypotension NOS Circulatory System 1.07 1.03 – 1.1 0.000137 4618 31186 all phecode
459 Other disorders of circulatory system Circulatory System 1.05 1.02 – 1.08 0.000206 7825 34792 all phecode
459.1 Hemorrhage NOS Circulatory System 1.04 0.963 – 1.12 0.326 834 8215 all phecode
459.7 Blood vessel replaced Circulatory System 1.09 1.02 – 1.15 0.00604 1305 13023 all phecode
459.9 Circulatory disease NEC Circulatory System 1.05 1.02 – 1.08 0.000332 6706 33592 all phecode
464 Acute sinusitis Respiratory 1.01 0.975 – 1.04 0.67 4792 32137 all phecode
465
Acute upper respiratory infections of multiple
Acute upper respiratory infections of multiple or unspecified sites
 Respiratory 1.01 0.983 – 1.03 0.547 9601 35915 all phecode
465.2 Acute pharyngitis Respiratory 1 0.974 – 1.04 0.791 5310 32365 all phecode
465.4 Acute laryngitis and tracheitis Respiratory 1 0.906 – 1.11 0.927 443 4428 all phecode
470 Septal Deviations/Turbinate Hypertrophy Respiratory 0.98 0.931 – 1.03 0.43 1797 17640 all phecode
471 Nasal polyps Respiratory 0.933 0.854 – 1.02 0.121 592 5881 all phecode
472 Chronic pharyngitis and nasopharyngitis Respiratory 0.992 0.942 – 1.04 0.759 1797 16986 all phecode
473 Diseases of the larynx and vocal cords Respiratory 1.03 0.987 – 1.07 0.193 2983 25244 all phecode
473.1 Chronic laryngitis Respiratory 0.992 0.762 – 1.29 0.954 68 674 all phecode
473.3 Paralysis/spasm of vocal cords or larynx Respiratory 0.979 0.898 – 1.07 0.621 628 6254 all phecode
473.4 Voice disturbance Respiratory 1.03 0.985 – 1.08 0.198 2336 21975 all phecode
474 Acute and chronic tonsillitis Respiratory 1 0.93 – 1.08 0.961 880 7892 all phecode
474.1 Acute tonsillitis Respiratory 0.96 0.852 – 1.08 0.51 335 3181 all phecode
474.2 Chronic tonsillitis and adenoiditis Respiratory 1.02 0.938 – 1.11 0.659 700 6445 all phecode
475 Chronic sinusitis Respiratory 1.02 0.985 – 1.05 0.279 4378 27891 all phecode
475.9 Postnasal drip Respiratory 0.988 0.92 – 1.06 0.739 922 9017 all phecode
476 Allergic rhinitis Respiratory 1 0.979 – 1.02 0.907 12687 28117 all phecode
477 Epistaxis or throat hemorrhage Respiratory 1.06 0.994 – 1.13 0.0776 1150 11318 all phecode
478 Throat pain Respiratory 1.05 0.943 – 1.17 0.379 426 4195 all phecode
479 Other upper respiratory disease Respiratory 1.02 0.985 – 1.05 0.318 5627 28048 all phecode
480 Pneumonia Respiratory 1.05 1.02 – 1.08 0.00108 5947 37034 all phecode
480.1 Bacterial pneumonia Respiratory 1.08 1.01 – 1.15 0.0224 1155 11495 all phecode
480.11 Pneumococcal pneumonia Respiratory 1.05 0.957 – 1.15 0.308 568 5644 all phecode
480.12 Pseudomonal pneumonia Respiratory 1.07 0.897 – 1.28 0.442 153 1523 all phecode
480.13 MRSA pneumonia Respiratory 1.08 0.892 – 1.31 0.429 117 1165 all phecode
480.2 Viral pneumonia Respiratory 1.05 0.908 – 1.22 0.49 202 1992 all phecode
480.3 Pneumonia due to fungus (mycoses) Respiratory 1.05 0.887 – 1.25 0.56 159 1590 all phecode
480.5 Bronchopneumonia and lung abscess Respiratory 1.18 0.977 – 1.42 0.0854 135 1312 all phecode
481 Influenza Respiratory 0.988 0.931 – 1.05 0.695 1355 13284 all phecode
483 Acute bronchitis and bronchiolitis Respiratory 1.02 0.98 – 1.06 0.363 3412 29871 all phecode
495 Asthma Respiratory 1.02 0.996 – 1.05 0.0936 8671 33569 all phecode
495.1 Chronic obstructive asthma Respiratory 1.02 0.915 – 1.13 0.747 397 3925 all phecode
495.11 Chronic obstructive asthma with exacerbation Respiratory 0.873 0.69 – 1.1 0.254 81 802 all phecode
495.2 Asthma with exacerbation Respiratory 0.972 0.921 – 1.03 0.305 1629 16033 all phecode
496 Chronic airway obstruction Respiratory 1.06 1.03 – 1.09 0.000353 5343 28343 all phecode
496.1 Emphysema Respiratory 1.05 1 – 1.1 0.0366 2134 19414 all phecode
496.2 Chronic bronchitis Respiratory 1.06 1.03 – 1.1 0.000454 4128 26624 all phecode
496.21 Obstructive chronic bronchitis Respiratory 1.06 1.03 – 1.1 0.000747 3747 25467 all phecode
496.3 Bronchiectasis Respiratory 1.02 0.928 – 1.12 0.706 549 5453 all phecode
497 Bronchitis Respiratory 1.02 0.97 – 1.07 0.456 1946 18824 all phecode
498 Acute bronchospasm Respiratory 1.01 0.917 – 1.11 0.83 496 4943 all phecode
499 Cystic fibrosis Respiratory 1.06 0.884 – 1.26 0.552 151 1510 all phecode
500 Lung disease due to external agents Respiratory 1.01 0.923 – 1.11 0.808 557 5551 all phecode
500.1 Extrinsic allergic alveolitis Respiratory 0.961 0.763 – 1.21 0.735 92 920 all phecode
500.2 Pneumoconiosis Respiratory 0.971 0.764 – 1.23 0.808 78 764 all phecode
501 Pneumonitis due to inhalation of food or vomitus Respiratory 1.05 0.967 – 1.15 0.236 634 6225 all phecode
502 Postinflammatory pulmonary fibrosis Respiratory 1.05 0.974 – 1.13 0.204 815 8076 all phecode
503 Pulmonary congestion and hypostasis Respiratory 1.16 1.08 – 1.25 8.77e-05 835 8243 all phecode
504 Other alveolar and parietoalveolar pneumonopathy Respiratory 1.03 0.945 – 1.13 0.485 595 5878 all phecode
504.1 Idiopathic fibrosing alveolitis Respiratory 1.02 0.903 – 1.15 0.75 311 3084 all phecode
505 Other pulmonary inflamation or edema Respiratory 1.07 1.02 – 1.13 0.0105 1638 15749 all phecode
506 Empyema and pneumothorax Respiratory 1.04 0.998 – 1.08 0.0636 2894 25235 all phecode
507 Pleurisy; pleural effusion Respiratory 1.02 0.981 – 1.06 0.296 2916 26208 all phecode
508
Pulmonary collapse; interstitial and
Pulmonary collapse; interstitial and compensatory emphysema
 Respiratory 1.03 0.987 – 1.08 0.165 2382 22588 all phecode
509 Respiratory failure, insufficiency, arrest Respiratory 1.07 1.03 – 1.11 0.000153 4032 29477 all phecode
509.1 Respiratory failure Respiratory 1.07 1.02 – 1.13 0.00553 1937 18949 all phecode
509.2 Respiratory insufficiency Respiratory 1.09 1.03 – 1.16 0.00546 1174 11679 all phecode
509.3
Pulmonary insufficiency or respiratory failure
Pulmonary insufficiency or respiratory failure following trauma and surgery
 Respiratory 1.09 1.03 – 1.15 0.00135 1689 16489 all phecode
509.8
Dependence on respirator [Ventilator] or
Dependence on respirator [Ventilator] or supplemental oxygen
 Respiratory 1.05 1 – 1.11 0.0436 1741 17249 all phecode
510 Other diseases of lung Respiratory 1.03 1 – 1.06 0.0528 5503 35907 all phecode
510.2 Lung transplant Respiratory 1.05 0.896 – 1.24 0.523 176 1757 all phecode
512 Other symptoms of respiratory system Respiratory 1.03 1.01 – 1.05 0.0029 18621 28154 all phecode
512.1 Wheezing Respiratory 1.02 0.959 – 1.08 0.59 1409 13516 all phecode
512.2 Painful respiration Respiratory 1 0.957 – 1.05 0.966 2309 21263 all phecode
512.3 Abnormal chest sounds Respiratory 1.04 0.916 – 1.17 0.572 291 2845 all phecode
512.7 Shortness of breath Respiratory 1.05 1.02 – 1.07 0.000236 10034 28081 all phecode
512.8 Cough Respiratory 1.03 1.01 – 1.06 0.0157 9501 28148 all phecode
512.9 Other dyspnea Respiratory 1.04 1.02 – 1.07 0.000418 10804 28104 all phecode
513 Respiratory abnormalities Respiratory 1.04 1.02 – 1.06 0.000513 12932 33822 all phecode
513.3 Hypoventilation Respiratory 1.07 0.996 – 1.15 0.0622 880 8646 all phecode
513.31 Apnea Respiratory 1.04 0.938 – 1.15 0.477 462 4607 all phecode
513.32 Orthopnea Respiratory 1.15 0.992 – 1.33 0.0647 220 2160 all phecode
513.4 Hyperventilation Respiratory 0.991 0.901 – 1.09 0.86 515 5124 all phecode
513.8 Disorders of diaphragm Respiratory 0.965 0.842 – 1.11 0.61 258 2557 all phecode
514 Abnormal findings examination of lungs Respiratory 1.02 0.987 – 1.05 0.27 5365 34834 all phecode
514.1
Abnormal results of function study of pulmonary
Abnormal results of function study of pulmonary system
 Respiratory 1.11 0.977 – 1.26 0.108 258 2580 all phecode
514.2 Solitary pulmonary nodule Respiratory 1 0.964 – 1.04 0.878 3018 27338 all phecode
516 Abnormal sputum Respiratory 1.06 0.979 – 1.15 0.153 735 7332 all phecode
516.1 Hemoptysis Respiratory 1.09 0.998 – 1.19 0.0565 611 6080 all phecode
519
Other diseases of respiratory system, not
Other diseases of respiratory system, not elsewhere classified
 Respiratory 1.07 1.04 – 1.1 8.34e-07 6458 39057 all phecode
519.1 Tracheostomy complications Respiratory 1.14 0.978 – 1.32 0.0957 214 2136 all phecode
519.2 Respiratory complications Respiratory 1.08 0.976 – 1.2 0.135 445 4430 all phecode
519.8 Other diseases of respiratory system, NEC Respiratory 1.06 1.01 – 1.12 0.0317 1588 15787 all phecode
519.9
Symptoms involving respiratory system and other
Symptoms involving respiratory system and other chest symptoms
 Respiratory 1.08 1.04 – 1.11 7.45e-06 4706 34489 all phecode
520 Disorders of tooth development Digestive 1.01 0.905 – 1.14 0.813 369 3690 all phecode
520.1 Hereditary disturbances in tooth structure Digestive 0.959 0.809 – 1.14 0.626 165 1642 all phecode
520.2 Disturbances in tooth eruption Digestive 1.02 0.882 – 1.18 0.778 218 2172 all phecode
521 Diseases of hard tissues of teeth Digestive 1.05 0.981 – 1.13 0.152 898 8954 all phecode
521.1 Dental caries Digestive 1.05 0.976 – 1.13 0.181 837 8349 all phecode
521.2 Dental abrasion, erosion and attrition Digestive 1.03 0.762 – 1.38 0.87 52 510 all phecode
522 Diseases of pulp and periapical tissues Digestive 1.16 1.05 – 1.27 0.00231 535 5340 all phecode
522.5 Periapical abscess Digestive 1.14 1.03 – 1.26 0.0128 459 4583 all phecode
523 Gingival and periodontal diseases Digestive 1.1 1.01 – 1.19 0.0266 718 7180 all phecode
523.1 Gingivitis Digestive 1.25 1.05 – 1.49 0.0143 142 1418 all phecode
523.3 Periodontitis (acute or chronic) Digestive 0.957 0.854 – 1.07 0.457 364 3636 all phecode
523.31 Acute periodontitis Digestive 0.95 0.839 – 1.08 0.424 311 3109 all phecode
523.32 Chronic periodontitis Digestive 0.964 0.792 – 1.17 0.71 122 1204 all phecode
524 Dentofacial anomalies, including malocclusion Digestive 0.977 0.871 – 1.1 0.691 363 3630 all phecode
524.3 Anomalies of tooth position/malocclusion Digestive 0.879 0.757 – 1.02 0.0912 220 2200 all phecode
525
Other diseases of the teeth and supporting
Other diseases of the teeth and supporting structures
 Digestive 1.09 1.02 – 1.17 0.0121 1039 10382 all phecode
525.1 Loss of teeth or edentulism Digestive 1.01 0.903 – 1.13 0.881 374 3731 all phecode
526 Diseases of the jaws Digestive 1 0.961 – 1.05 0.909 2680 26455 all phecode
526.1 Cysts of the jaws Digestive 0.995 0.863 – 1.15 0.94 247 2470 all phecode
526.3 Anomalies of jaw size/symmetry Digestive 0.838 0.727 – 0.965 0.0143 241 2383 all phecode
526.4 Temporomandibular joint disorders Digestive 0.996 0.941 – 1.05 0.881 1504 15025 all phecode
526.41 Temporomandibular joint disorder, unspecified Digestive 0.989 0.928 – 1.05 0.727 1187 11858 all phecode
526.42 Arthralgia/ankylosis of temporomandibular joint Digestive 1 0.926 – 1.09 0.949 741 7400 all phecode
526.5 Inflammatory conditions of jaw Digestive 1.06 0.93 – 1.2 0.403 287 2864 all phecode
526.8 Exostosis of jaw Digestive 1.14 0.847 – 1.55 0.379 53 521 all phecode
526.9 Jaw disease NOS Digestive 0.953 0.865 – 1.05 0.337 487 4867 all phecode
527 Diseases of the salivary glands Digestive 0.995 0.946 – 1.05 0.858 1781 17771 all phecode
527.1 Hypertrophy of salivary gland Digestive 1.13 0.856 – 1.49 0.391 58 579 all phecode
527.2 Sialoadenitis Digestive 0.963 0.864 – 1.07 0.494 394 3936 all phecode
527.7 Disturbance of salivary secretion Digestive 0.983 0.916 – 1.05 0.625 952 9481 all phecode
527.8 Other specified diseases of the salivary glands Digestive 1.03 0.9 – 1.17 0.693 254 2540 all phecode
528
Diseases of the oral soft tissues, excluding
Diseases of the oral soft tissues, excluding lesions specific for gingiva and tongue
 Digestive 0.98 0.94 – 1.02 0.356 2643 26197 all phecode
528.1 Stomatitis and mucositis Digestive 1.01 0.925 – 1.09 0.888 668 6657 all phecode
528.11 Stomatitis and mucositis (ulcerative) Digestive 1.06 0.916 – 1.23 0.429 211 2110 all phecode
528.12 Oral aphthae Digestive 0.961 0.832 – 1.11 0.586 215 2137 all phecode
528.3 Cellulitis and abscess of oral soft tissues Digestive 0.913 0.792 – 1.05 0.21 235 2338 all phecode
528.4 Cysts of oral soft tissues Digestive 1 0.83 – 1.21 0.975 124 1229 all phecode
528.41 Cyst of the salivary gland Digestive 0.956 0.75 – 1.22 0.717 77 760 all phecode
528.5 Diseases of lips Digestive 0.925 0.838 – 1.02 0.125 462 4602 all phecode
528.6 Leukoplakia of oral mucosa Digestive 0.898 0.745 – 1.08 0.258 137 1370 all phecode
528.7 Sialolithiasis Digestive 1 0.844 – 1.19 0.993 163 1623 all phecode
529 Diseases and other conditions of the tongue Digestive 1.03 0.95 – 1.12 0.457 690 6878 all phecode
529.1 Glossitis Digestive 1.06 0.871 – 1.28 0.57 129 1281 all phecode
529.6 Glossodynia Digestive 1.11 0.944 – 1.31 0.205 168 1652 all phecode
530 Diseases of esophagus Digestive 1.04 1.02 – 1.07 3.6e-05 17081 27931 all phecode
530.1 Esophagitis, GERD and related diseases Digestive 1.05 1.03 – 1.07 9.16e-06 16572 27931 all phecode
530.11 GERD Digestive 1.05 1.03 – 1.07 1.02e-05 16143 27929 all phecode
530.12 Ulcer of esophagus Digestive 1.07 0.957 – 1.19 0.244 400 3983 all phecode
530.13 Barrett's esophagus Digestive 1.05 0.973 – 1.14 0.202 762 7584 all phecode
530.14 Reflux esophagitis Digestive 1.03 0.976 – 1.08 0.323 1900 17495 all phecode
530.15 Eosinophilic esophagitis Digestive 0.937 0.812 – 1.08 0.378 221 2210 all phecode
530.2 Esophageal bleeding (varices/hemorrhage) Digestive 1.1 1.01 – 1.19 0.0369 651 6473 all phecode
530.3 Stricture and stenosis of esophagus Digestive 1.02 0.95 – 1.1 0.575 911 8971 all phecode
530.5 Disorders of esophageal motility Digestive 1.04 0.949 – 1.14 0.396 548 5432 all phecode
530.6 Diverticulum of esophagus, acquired Digestive 0.885 0.733 – 1.07 0.201 129 1265 all phecode
530.7 Gastroesophageal laceration-hemorrhage syndrome Digestive 0.89 0.707 – 1.12 0.32 82 812 all phecode
530.9 Heartburn Digestive 1.07 1.01 – 1.13 0.0198 1519 14928 all phecode
531 Peptic ulcer (excl. esophageal) Digestive 1.02 0.976 – 1.07 0.346 2073 20617 all phecode
531.1 Hemorrhage from gastrointestinal ulcer Digestive 0.981 0.88 – 1.09 0.722 391 3883 all phecode
531.2 Gastric ulcer Digestive 1.03 0.965 – 1.09 0.405 1201 11970 all phecode
531.3 Duodenal ulcer Digestive 1 0.907 – 1.11 0.934 467 4640 all phecode
531.4 Peptic ulcer, site unspecified Digestive 1.02 0.947 – 1.1 0.577 804 8018 all phecode
531.5 Gastrojejunal ulcer Digestive 1.03 0.872 – 1.23 0.699 150 1500 all phecode
532 Dysphagia Digestive 1.03 1 – 1.07 0.0317 5585 26852 all phecode
535 Gastritis and duodenitis Digestive 1.05 1 – 1.09 0.0317 2799 27335 all phecode
535.1 Acute gastritis Digestive 1.05 0.982 – 1.11 0.164 1178 11750 all phecode
535.2 Atrophic gastritis Digestive 0.952 0.847 – 1.07 0.416 344 3413 all phecode
535.6 Duodenitis Digestive 1.06 0.94 – 1.19 0.344 334 3337 all phecode
535.8 Other specified gastritis Digestive 0.995 0.913 – 1.08 0.905 638 6354 all phecode
535.9 Gastritis and duodenitis, NOS Digestive 1.07 1.01 – 1.14 0.0234 1255 12511 all phecode
536 Disorders of function of stomach Digestive 1.03 0.986 – 1.07 0.206 2911 27685 all phecode
536.3 Gastroparesis Digestive 1.05 0.966 – 1.14 0.256 706 6901 all phecode
536.7
Complications of gastrostomy, colostomy and
Complications of gastrostomy, colostomy and enterostomy
 Digestive 1.06 0.954 – 1.18 0.275 407 4059 all phecode
536.8
Dyspepsia and other specified disorders of
Dyspepsia and other specified disorders of function of stomach
 Digestive 1.02 0.972 – 1.07 0.447 2150 21094 all phecode
537 Other disorders of stomach and duodenum Digestive 1.02 0.979 – 1.06 0.379 3183 30048 all phecode
537.1 Lesions of stomach and duodenum Digestive 1.04 0.879 – 1.22 0.674 173 1725 all phecode
539 Bariatric surgery Digestive 1.02 0.962 – 1.07 0.555 1509 15074 all phecode
540 Appendiceal conditions Digestive 0.983 0.891 – 1.08 0.725 495 4948 all phecode
540.1 Appendicitis Digestive 0.963 0.866 – 1.07 0.49 425 4239 all phecode
540.11 Acute appendicitis Digestive 0.972 0.866 – 1.09 0.633 353 3511 all phecode
550 Abdominal hernia Digestive 1.04 1.01 – 1.07 0.0094 6768 37731 all phecode
550.1 Inguinal hernia Digestive 0.979 0.93 – 1.03 0.429 1744 16488 all phecode
550.2 Diaphragmatic hernia Digestive 1.05 1.01 – 1.09 0.026 2817 25849 all phecode
550.3 Femoral hernia Digestive 1.04 0.863 – 1.26 0.677 131 1291 all phecode
550.4 Umbilical hernia Digestive 0.996 0.938 – 1.06 0.901 1313 13110 all phecode
550.5 Ventral hernia Digestive 1.08 1.03 – 1.13 0.00164 2241 22163 all phecode
550.6 Incisional hernia Digestive 1.08 1.01 – 1.14 0.0155 1313 13111 all phecode
555
Inflammatory bowel disease and other
Inflammatory bowel disease and other gastroenteritis and colitis
 Digestive 1.04 0.983 – 1.1 0.172 1536 15153 all phecode
555.1 Regional enteritis Digestive 1.07 0.996 – 1.15 0.0658 919 9095 all phecode
555.2 Ulcerative colitis Digestive 1.03 0.959 – 1.1 0.429 937 9315 all phecode
555.21 Ulcerative colitis (chronic) Digestive 0.997 0.909 – 1.09 0.956 537 5315 all phecode
556 Ulceration of the lower GI tract Digestive 1.05 0.966 – 1.15 0.242 632 6267 all phecode
556.1 Ulceration of intestine Digestive 1.05 0.961 – 1.15 0.27 551 5451 all phecode
556.11
Angiodysplasia of intestine (without mention of
Angiodysplasia of intestine (without mention of hemorrhage)
 Digestive 0.956 0.826 – 1.11 0.548 214 2093 all phecode
557 Intestinal malabsorption (non-celiac) Digestive 0.999 0.948 – 1.05 0.969 1716 16490 all phecode
557.1 Celiac disease Digestive 0.972 0.874 – 1.08 0.601 421 4026 all phecode
558 Noninfectious gastroenteritis Digestive 1.06 1.03 – 1.1 0.00109 3458 26408 all phecode
559 Ileostomy status Digestive 1.11 1.04 – 1.19 0.00241 957 9565 all phecode
560 Intestinal obstruction without mention of hernia Digestive 1.03 0.994 – 1.08 0.0917 3004 24851 all phecode
560.1 Paralytic ileus Digestive 0.998 0.946 – 1.05 0.937 1627 15714 all phecode
560.2 Impaction of intestine Digestive 1.1 0.984 – 1.23 0.0936 387 3779 all phecode
560.3 Peritoneal or intestinal adhesions Digestive 1.01 0.89 – 1.16 0.827 266 2647 all phecode
560.4 Other intestinal obstruction Digestive 1.02 0.971 – 1.08 0.372 1651 16170 all phecode
561 Symptoms involving digestive system Digestive 1.05 1.01 – 1.1 0.0264 2608 21766 all phecode
562 Diverticulosis and diverticulitis Digestive 1.01 0.978 – 1.04 0.619 6295 23431 all phecode
562.1 Diverticulosis Digestive 1.01 0.977 – 1.04 0.651 6246 23383 all phecode
562.2 Diverticulitis Digestive 1.08 1.03 – 1.14 0.00392 1611 15162 all phecode
564 Functional digestive disorders Digestive 1.04 1.02 – 1.07 0.000749 11411 28676 all phecode
564.1 Irritable Bowel Syndrome Digestive 1.07 1.03 – 1.11 0.00045 3457 22266 all phecode
564.9 Personal history of diseases of digestive system Digestive 1.04 1 – 1.08 0.0361 3074 25861 all phecode
565 Anal and rectal conditions Digestive 1.03 0.992 – 1.07 0.119 3355 30757 all phecode
565.1 Anal and rectal polyp Digestive 1.02 0.961 – 1.08 0.503 1305 12649 all phecode
567 Peritonitis and retroperitoneal infections Digestive 1.06 1 – 1.13 0.037 1364 13616 all phecode
568 Other disorders of peritoneum Digestive 1.06 1.01 – 1.12 0.0267 1705 17038 all phecode
568.1
Peritoneal adhesions (postoperative)
Peritoneal adhesions (postoperative) (postinfection)
 Digestive 1.06 0.998 – 1.13 0.0589 1247 12468 all phecode
569 Other disorders of intestine Digestive 1.03 1 – 1.05 0.0545 8079 35231 all phecode
569.1 Toxic gastroenteritis and colitis Digestive 1.19 1.06 – 1.34 0.00442 326 3260 all phecode
569.2 Gastrointestinal complications Digestive 1.03 0.968 – 1.09 0.393 1395 13933 all phecode
571 Chronic liver disease and cirrhosis Digestive 1.12 1.08 – 1.16 1.02e-11 4610 32562 all phecode
571.5 Other chronic nonalcoholic liver disease Digestive 1.12 1.09 – 1.16 1.35e-11 4342 32234 all phecode
571.51 Cirrhosis of liver without mention of alcohol Digestive 1.11 1.04 – 1.19 0.00266 1018 10095 all phecode
571.6 Primary biliary cirrhosis Digestive 1.09 0.921 – 1.28 0.327 179 1790 all phecode
571.8
Liver abscess and sequelae of chronic liver
Liver abscess and sequelae of chronic liver disease
 Digestive 1.07 0.997 – 1.15 0.0601 950 9498 all phecode
571.81 Portal hypertension Digestive 1.03 0.945 – 1.13 0.465 573 5730 all phecode
572 Ascites (non malignant) Digestive 1.02 0.978 – 1.07 0.315 2278 22675 all phecode
573 Other disorders of liver Digestive 1.09 1.06 – 1.12 3.58e-08 5599 33620 all phecode
573.1 Chronic passive congestion of liver Digestive 1.13 0.946 – 1.36 0.176 136 1359 all phecode
573.2 Liver replaced by transplant Digestive 0.968 0.851 – 1.1 0.618 292 2920 all phecode
573.3 Hepatomegaly Digestive 1.13 1.02 – 1.25 0.0184 470 4700 all phecode
573.4 Acute and subacute necrosis of liver Digestive 1.11 0.985 – 1.25 0.0874 316 3149 all phecode
573.5 Jaundice (not of newborn) Digestive 1.09 1.01 – 1.16 0.0196 958 9496 all phecode
573.6
Nonspecific elevation of levels of transaminase
Nonspecific elevation of levels of transaminase or lactic acid dehydrogenase [LDH]
 Digestive 1.05 1.01 – 1.09 0.0261 2756 26470 all phecode
573.7 Abnormal results of function study of liver Digestive 1.05 1.01 – 1.09 0.0116 3018 27774 all phecode
573.9 Abnormal serum enzyme levels Digestive 1.06 1.02 – 1.09 0.00104 4679 33866 all phecode
574 Cholelithiasis and cholecystitis Digestive 1.01 0.974 – 1.05 0.533 3177 30809 all phecode
574.1 Cholelithiasis Digestive 1.01 0.974 – 1.06 0.489 2924 28874 all phecode
574.11 Cholelithiasis with acute cholecystitis Digestive 0.893 0.794 – 1 0.0605 342 3412 all phecode
574.12 Cholelithiasis with other cholecystitis Digestive 0.92 0.838 – 1.01 0.0771 553 5501 all phecode
574.2 Calculus of bile duct Digestive 0.957 0.888 – 1.03 0.244 852 8503 all phecode
574.3 Cholecystitis without cholelithiasis Digestive 0.959 0.889 – 1.03 0.281 822 8181 all phecode
575 Other biliary tract disease Digestive 0.982 0.939 – 1.03 0.435 2266 22555 all phecode
575.1 Cholangitis Digestive 1.02 0.907 – 1.14 0.783 354 3530 all phecode
575.2 Obstruction of bile duct Digestive 1.01 0.925 – 1.1 0.865 621 6201 all phecode
575.6 Cholesterolosis of gallbladder Digestive 0.989 0.853 – 1.15 0.881 207 2063 all phecode
575.7 Other disorders of gallbladder Digestive 0.959 0.894 – 1.03 0.245 939 9382 all phecode
575.8 Other disorders of biliary tract Digestive 0.992 0.931 – 1.06 0.803 1154 11523 all phecode
575.9
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of biliary tract
 Digestive 0.888 0.775 – 1.02 0.0849 260 2600 all phecode
577 Diseases of pancreas Digestive 1.06 1.01 – 1.11 0.0113 2225 22106 all phecode
577.1 Acute pancreatitis Digestive 1.07 1.01 – 1.14 0.0333 1212 12110 all phecode
577.2 Chronic pancreatitis Digestive 1.14 1.03 – 1.26 0.00794 495 4950 all phecode
577.3 Cyst and pseudocyst of pancreas Digestive 1.02 0.933 – 1.12 0.66 570 5601 all phecode
578 Gastrointestinal hemorrhage Digestive 1.02 0.989 – 1.06 0.193 4554 37045 all phecode
578.1 Hematemesis Digestive 1.07 0.968 – 1.18 0.188 485 4842 all phecode
578.2 Blood in stool Digestive 1.05 1 – 1.09 0.0357 2743 26554 all phecode
578.8 Hemorrhage of rectum and anus Digestive 0.987 0.943 – 1.03 0.579 2210 21750 all phecode
578.9 Hemorrhage of gastrointestinal tract Digestive 1.06 1 – 1.12 0.0363 1562 15345 all phecode
579 Other symptoms involving abdomen and pelvis Digestive 1.06 1.03 – 1.1 0.000328 4431 34209 all phecode
579.2 Splenomegaly Digestive 1.1 1.02 – 1.2 0.017 730 7262 all phecode
579.8 Nonspecific abnormal findings in stool contents Digestive 1.02 0.959 – 1.08 0.589 1410 13877 all phecode
580 Nephritis; nephrosis; renal sclerosis Genitourinary 1.13 1.07 – 1.19 3.43e-06 1881 15516 all phecode
580.1 Glomerulonephritis Genitourinary 1.08 0.966 – 1.2 0.185 401 3992 all phecode
580.11 Proliferative glomerulonephritis Genitourinary 1.06 0.886 – 1.27 0.524 146 1440 all phecode
580.12 Non-proliferative glomerulonephritis Genitourinary 1.14 0.935 – 1.39 0.194 114 1128 all phecode
580.13 Acute glomerulonephritis, NOS Genitourinary 1.01 0.764 – 1.35 0.923 61 600 all phecode
580.14 Chronic glomerulonephritis, NOS Genitourinary 1.13 0.993 – 1.28 0.0631 277 2760 all phecode
580.2
Nephrotic syndrome without mention of
Nephrotic syndrome without mention of glomerulonephritis
 Genitourinary 1.29 1.12 – 1.49 0.000521 221 2193 all phecode
580.3
Nephritis and nephropathy without mention of
Nephritis and nephropathy without mention of glomerulonephritis
 Genitourinary 1.14 1.07 – 1.2 1.71e-05 1502 11930 all phecode
580.31
Nephritis and nephropathy in diseases
Nephritis and nephropathy in diseases classified elsewhere
 Genitourinary 1.17 1.09 – 1.26 1.79e-05 992 7228 all phecode
580.32
Nephritis and nephropathy with pathological
Nephritis and nephropathy with pathological lesion
 Genitourinary 1.11 1.02 – 1.2 0.0191 683 6612 all phecode
580.4 Renal sclerosis, NOS Genitourinary 1.09 0.969 – 1.22 0.154 340 3400 all phecode
585 Renal failure Genitourinary 1.09 1.06 – 1.12 4.24e-10 7470 32340 all phecode
585.1 Acute renal failure Genitourinary 1.1 1.06 – 1.14 4.3e-08 4265 27230 all phecode
585.2 Renal failure NOS Genitourinary 1.1 1.02 – 1.19 0.0121 832 8162 all phecode
585.3 Chronic renal failure [CKD] Genitourinary 1.09 1.06 – 1.12 5.35e-08 5580 29470 all phecode
585.31 Renal dialysis Genitourinary 1.09 1.01 – 1.18 0.0281 747 7423 all phecode
585.32 End stage renal disease Genitourinary 1.09 1.02 – 1.17 0.0151 1007 9783 all phecode
585.33 Chronic Kidney Disease, Stage III Genitourinary 1.09 1.05 – 1.13 2.77e-05 3209 21312 all phecode
585.34 Chronic Kidney Disease, Stage IV Genitourinary 1.1 1.02 – 1.18 0.00888 977 9190 all phecode
585.4 Chronic kidney disease, Stage I or II Genitourinary 1.07 1.01 – 1.14 0.0309 1227 11191 all phecode
586 Other disorders of the kidney and ureters Genitourinary 1.07 1.04 – 1.1 2.57e-06 7628 34189 all phecode
586.1 Anatomical abnormatilies of kidney and ureters Genitourinary 1.15 1.02 – 1.29 0.0178 349 3480 all phecode
586.11 Small kidney Genitourinary 1.21 1.05 – 1.41 0.0102 210 2093 all phecode
586.12 Vesicoureteral reflux Genitourinary 1.09 0.901 – 1.31 0.386 136 1360 all phecode
586.2 Cyst of kidney, acquired Genitourinary 1.02 0.965 – 1.08 0.442 1381 12912 all phecode
586.3 Vascular disorders of kidney/hypertrophy Genitourinary 1.11 0.948 – 1.3 0.196 187 1862 all phecode
586.4 Stricture/obstruction of ureter Genitourinary 1.05 0.995 – 1.1 0.0795 1821 17115 all phecode
587 Kidney replaced by transpant Genitourinary 1.06 0.978 – 1.14 0.166 819 8134 all phecode
588 Disorders resulting from impaired renal function Genitourinary 1.09 1.01 – 1.17 0.018 976 9389 all phecode
588.1 Renal osteodystrophy Genitourinary 1.09 0.956 – 1.24 0.2 290 2900 all phecode
588.2 Secondary hyperparathyroidism (of renal origin) Genitourinary 1.06 0.976 – 1.15 0.17 755 7275 all phecode
589 Abnormal results of function study of kidney Genitourinary 1.03 0.96 – 1.1 0.435 1007 9834 all phecode
590 Pyelonephritis Genitourinary 1.1 1.04 – 1.16 0.00127 1461 14350 all phecode
591 Urinary tract infection Genitourinary 1.02 0.995 – 1.04 0.126 9873 32513 all phecode
592 Cystitis and urethritis Genitourinary 1.01 0.968 – 1.05 0.731 3038 24207 all phecode
592.1 Cystitis Genitourinary 1.01 0.967 – 1.05 0.722 2880 23279 all phecode
592.11 Acute cystitis Genitourinary 1 0.954 – 1.06 0.857 1783 16452 all phecode
592.12 Chronic cystitis Genitourinary 1.08 0.935 – 1.24 0.299 239 2343 all phecode
592.13 Chronic interstitial cystitis Genitourinary 1.08 0.972 – 1.2 0.154 431 4310 all phecode
592.2 Urethritis and urethral syndrome Genitourinary 0.96 0.824 – 1.12 0.603 210 2093 all phecode
593 Hematuria Genitourinary 1.03 0.999 – 1.07 0.0559 4859 32063 all phecode
593.1 Gross hematuria Genitourinary 1.02 0.968 – 1.08 0.424 1585 14824 all phecode
593.2 Microscopic hematuria Genitourinary 1.03 0.966 – 1.1 0.35 1049 10301 all phecode
594 Urinary calculus Genitourinary 1.06 1.03 – 1.09 1.01e-05 6707 38209 all phecode
594.1 Calculus of kidney Genitourinary 1.06 1.03 – 1.09 7.49e-05 6273 38051 all phecode
594.2 Calculus of lower urinary tract Genitourinary 1.16 1.04 – 1.31 0.00904 366 3638 all phecode
594.3 Calculus of ureter Genitourinary 1.04 0.984 – 1.11 0.156 1361 13561 all phecode
594.8 Renal colic Genitourinary 1.03 0.922 – 1.16 0.573 356 3560 all phecode
595 Hydronephrosis Genitourinary 1.07 1.01 – 1.13 0.0152 1670 16658 all phecode
596 Other disorders of bladder Genitourinary 1.01 0.975 – 1.05 0.485 3074 28020 all phecode
596.1 Bladder neck obstruction Genitourinary 0.912 0.818 – 1.02 0.0987 400 3942 all phecode
596.5 Functional disorders of bladder Genitourinary 1.02 0.965 – 1.07 0.528 1719 17049 all phecode
597 Other disorders of urethra and urinary tract Genitourinary 0.964 0.906 – 1.03 0.255 1211 11998 all phecode
597.1 Urethral stricture (not specified as infectious) Genitourinary 0.919 0.844 – 1 0.0529 661 6537 all phecode
597.2 Urinary complications NEC Genitourinary 0.992 0.928 – 1.06 0.82 1049 10479 all phecode
597.8 Urethral hypermobility/ISD Genitourinary 1.09 0.938 – 1.27 0.255 189 1873 all phecode
598 Abnormal findings on examination of urine Genitourinary 0.978 0.818 – 1.17 0.804 138 1356 all phecode
598.4 Other cells and casts in urine Genitourinary 1.01 0.83 – 1.22 0.958 122 1192 all phecode
599 Other symptoms/disorders or the urinary system Genitourinary 1.01 0.988 – 1.03 0.402 14168 30681 all phecode
599.1 Urinary obstruction Genitourinary 1.01 0.93 – 1.09 0.862 728 6861 all phecode
599.2 Retention of urine Genitourinary 1.02 0.986 – 1.05 0.283 5034 28305 all phecode
599.3 Dysuria Genitourinary 1.02 0.988 – 1.06 0.212 4397 27849 all phecode
599.4 Urinary incontinence Genitourinary 1.01 0.977 – 1.04 0.64 5599 26960 all phecode
599.5 Frequency of urination and polyuria Genitourinary 1.02 0.99 – 1.05 0.19 5498 28723 all phecode
599.6 Oliguria and anuria Genitourinary 1.04 0.95 – 1.13 0.414 599 5902 all phecode
599.7 Urethral discharge Genitourinary 0.882 0.732 – 1.06 0.187 118 1175 all phecode
599.8 Other symptoms involving urinary system Genitourinary 1.02 0.992 – 1.05 0.151 5446 27963 all phecode
599.9 Other abnormality of urination Genitourinary 1 0.966 – 1.05 0.823 3041 24877 all phecode
600 Hyperplasia of prostate Genitourinary 0.999 0.96 – 1.04 0.979 4063 11364 all phecode
601 Inflammatory diseases of prostate Genitourinary 1.01 0.946 – 1.08 0.725 1044 9665 all phecode
601.1 Prostatitis Genitourinary 0.966 0.875 – 1.07 0.502 477 4596 all phecode
601.11 Acute prostatitis Genitourinary 0.866 0.719 – 1.04 0.132 124 1200 all phecode
601.12 Chronic prostatitis Genitourinary 0.906 0.724 – 1.13 0.391 95 943 all phecode
601.3 Orchitis and epididymitis Genitourinary 1.11 0.994 – 1.24 0.0637 389 3822 all phecode
601.4 Balanoposthitis Genitourinary 0.913 0.759 – 1.1 0.333 127 1224 all phecode
601.8
Other inflammatory disorders of male genital
Other inflammatory disorders of male genital organs
 Genitourinary 1.06 0.891 – 1.26 0.51 161 1591 all phecode
602 Other disorders of prostate Genitourinary 1.09 0.967 – 1.22 0.162 361 3399 all phecode
602.3 Dysplasia of prostate Genitourinary 1.12 0.873 – 1.45 0.364 77 730 all phecode
603 Other disorders of testis Genitourinary 0.974 0.878 – 1.08 0.623 440 4354 all phecode
603.1 Hydrocele Genitourinary 0.957 0.844 – 1.09 0.498 293 2882 all phecode
603.2 Spermatocele Genitourinary 1 0.839 – 1.2 0.965 156 1539 all phecode
604 Disorders of penis Genitourinary 0.98 0.903 – 1.06 0.633 685 6748 all phecode
604.1 Redundant prepuce and phimosis/BXO Genitourinary 0.979 0.822 – 1.17 0.81 155 1540 all phecode
604.3 Peyronie's disease Genitourinary 1.02 0.885 – 1.18 0.754 215 2132 all phecode
605 Erectile dysfunction [ED] Genitourinary 1.01 0.972 – 1.05 0.576 3776 12700 all phecode
608 Other disorders of male genital organs Genitourinary 1.03 0.971 – 1.08 0.363 1645 13758 all phecode
609 Male infertility and abnormal spermatozoa Genitourinary 0.806 0.724 – 0.898 9.63e-05 424 4196 all phecode
609.1 Infertility, male Genitourinary 0.828 0.729 – 0.94 0.00361 302 2992 all phecode
609.11 Azoospermia and oligospermia Genitourinary 0.853 0.684 – 1.06 0.158 95 950 all phecode
609.2 Abnormal spermatozoa Genitourinary 0.708 0.593 – 0.847 0.000153 154 1519 all phecode
610 Benign mammary dysplasias Genitourinary 0.975 0.939 – 1.01 0.198 3683 16548 all phecode
610.1 Cystic mastopathy Genitourinary 0.954 0.903 – 1.01 0.0862 1633 14191 all phecode
610.2 Fibroadenosis of breast Genitourinary 1.11 0.845 – 1.46 0.447 60 600 all phecode
610.4 Benign neoplasm of breast Genitourinary 0.976 0.935 – 1.02 0.256 2837 16430 all phecode
610.8 Other specified benign mammary dysplasias Genitourinary 0.937 0.881 – 0.996 0.0368 1269 12191 all phecode
611 Abnormal findings on mammogram or breast exam Genitourinary 0.983 0.953 – 1.01 0.293 6067 18690 all phecode
611.1 Abnormal mammogram Genitourinary 0.969 0.937 – 1 0.0705 4980 16120 all phecode
611.11 Mammographic microcalcification Genitourinary 0.976 0.914 – 1.04 0.464 1122 10394 all phecode
611.3 Lump or mass in breast Genitourinary 0.979 0.942 – 1.02 0.265 3549 18572 all phecode
612
Breast conditions, congenital or relating to
Breast conditions, congenital or relating to hormones
 Genitourinary 0.988 0.924 – 1.06 0.726 1051 10425 all phecode
612.1 Galactorrhea Genitourinary 0.9 0.752 – 1.08 0.251 139 1390 all phecode
612.2 Hypertrophy of breast (Gynecomastia) Genitourinary 1.02 0.944 – 1.1 0.629 800 7962 all phecode
612.3 Congenital anomalies of breast Genitourinary 0.911 0.713 – 1.16 0.453 83 810 all phecode
613 Other nonmalignant breast conditions Genitourinary 1.03 0.992 – 1.07 0.126 3897 22072 all phecode
613.1 Inflammatory disease of breast Genitourinary 1 0.919 – 1.1 0.922 593 5874 all phecode
613.5 Mastodynia Genitourinary 1.04 0.99 – 1.1 0.111 1675 16203 all phecode
613.7 Other signs and symptoms in breast Genitourinary 0.99 0.921 – 1.06 0.789 883 8754 all phecode
613.8 Other specified disorders of breast Genitourinary 0.964 0.898 – 1.03 0.311 932 9248 all phecode
613.9 Breast disorder NOS Genitourinary 1.04 0.982 – 1.1 0.182 1465 14174 all phecode
614 Inflammatory diseases of female pelvic organs Genitourinary 1.02 0.982 – 1.06 0.318 3715 19647 all phecode
614.1
Pelvic peritoneal adhesions, female
Pelvic peritoneal adhesions, female (postoperative) (postinfection)
 Genitourinary 1.05 0.93 – 1.18 0.45 337 3370 all phecode
614.3 Pelvic inflammatory disease (PID) Genitourinary 1.06 0.957 – 1.16 0.279 478 4773 all phecode
614.31 Acute inflammatory pelvic disease Genitourinary 1.13 0.898 – 1.41 0.304 94 933 all phecode
614.32 Chronic inflammatory pelvic disease Genitourinary 0.973 0.829 – 1.14 0.735 186 1842 all phecode
614.33 Pelvic inflammatory disease, NOS Genitourinary 1.04 0.908 – 1.19 0.57 246 2460 all phecode
614.4 Inflammatory diseases of uterus, except cervix Genitourinary 0.985 0.834 – 1.16 0.857 165 1639 all phecode
614.5
Inflammatory disease of cervix, vagina, and
Inflammatory disease of cervix, vagina, and vulva
 Genitourinary 1.01 0.974 – 1.05 0.53 3180 19539 all phecode
614.51 Cervicitis and endocervicitis Genitourinary 0.996 0.869 – 1.14 0.951 264 2640 all phecode
614.52 Vaginitis and vulvovaginitis Genitourinary 1.01 0.966 – 1.05 0.722 2732 18924 all phecode
614.53 Cyst or abscess of Bartholin's gland Genitourinary 0.961 0.797 – 1.16 0.677 132 1311 all phecode
614.54 Abscess or ulceration of vulva Genitourinary 1 0.869 – 1.15 0.988 225 2244 all phecode
615 Endometriosis Genitourinary 1.01 0.959 – 1.07 0.658 1585 14666 all phecode
618 Genital prolapse Genitourinary 1.01 0.96 – 1.06 0.779 2079 17915 all phecode
618.1 Prolapse of vaginal walls Genitourinary 0.983 0.928 – 1.04 0.557 1408 13456 all phecode
618.2 Uterine/Uterovaginal prolapse Genitourinary 0.994 0.906 – 1.09 0.891 542 5390 all phecode
618.5 Prolapse of vaginal vault after hysterectomy Genitourinary 1.11 0.981 – 1.25 0.0971 317 3162 all phecode
618.6 Vaginal enterocele, congenital or acquired Genitourinary 1.05 0.947 – 1.16 0.374 441 4394 all phecode
619 Noninflammatory female genital disorders Genitourinary 1.03 0.997 – 1.06 0.0786 5728 18687 all phecode
619.1
Noninflammatory disorders of ovary, fallopian
Noninflammatory disorders of ovary, fallopian tube, and broad ligament
 Genitourinary 1.03 0.966 – 1.09 0.382 1233 12082 all phecode
619.2 Disorders of uterus, NEC Genitourinary 1.02 0.934 – 1.12 0.653 591 5897 all phecode
619.3 Noninflammatory disorders of cervix Genitourinary 1.03 0.937 – 1.14 0.506 483 4823 all phecode
619.4 Noninflammatory disorders of vagina Genitourinary 1.03 0.986 – 1.08 0.183 2525 18404 all phecode
619.5 Noninflammatory disorders of vulva and perineum Genitourinary 1.03 0.971 – 1.1 0.308 1189 11717 all phecode
620 Dysplasia of female genital organs Genitourinary 0.976 0.876 – 1.09 0.664 395 3950 all phecode
620.1 Dysplasia of cervix Genitourinary 0.9 0.766 – 1.06 0.195 178 1780 all phecode
621 Endometrial hyperplasia Genitourinary 0.951 0.857 – 1.05 0.338 437 4370 all phecode
622 Polyp of female genital organs Genitourinary 0.939 0.887 – 0.994 0.0304 1449 14264 all phecode
622.1 Polyp of corpus uteri Genitourinary 0.951 0.891 – 1.01 0.123 1132 11189 all phecode
622.2 Mucous polyp of cervix Genitourinary 0.893 0.805 – 0.989 0.0305 445 4444 all phecode
623 Hypertrophy of female genital organs Genitourinary 1 0.93 – 1.08 0.941 824 8165 all phecode
624 Symptoms involving female genital tract Genitourinary 1.05 0.99 – 1.11 0.106 1348 12518 all phecode
624.1 Dystrophy of female genital tract Genitourinary 1.19 1.02 – 1.38 0.0236 216 2155 all phecode
624.2 Atrophy of female genital tract Genitourinary 1.32 1 – 1.74 0.0475 64 615 all phecode
624.9 stress incontinence, female Genitourinary 0.997 0.948 – 1.05 0.899 1935 15408 all phecode
625
Pain and other symptoms associated with female
Pain and other symptoms associated with female genital organs
 Genitourinary 1.03 1 – 1.07 0.0341 5653 17303 all phecode
625.1 Dyspareunia Genitourinary 0.973 0.916 – 1.03 0.386 1267 12474 all phecode
626
Disorders of menstruation and other abnormal
Disorders of menstruation and other abnormal bleeding from female genital tract
 Genitourinary 1.01 0.981 – 1.05 0.416 5940 15585 all phecode
626.1 Irregular menstrual cycle/bleeding Genitourinary 1.02 0.984 – 1.06 0.268 4315 14604 all phecode
626.11 Absent or infrequent menstruation Genitourinary 0.999 0.935 – 1.07 0.985 1062 8531 all phecode
626.12 Excessive or frequent menstruation Genitourinary 1.03 0.978 – 1.08 0.282 2097 11991 all phecode
626.13 Irregular menstrual cycle Genitourinary 1.02 0.974 – 1.08 0.356 1957 12265 all phecode
626.14 Irregular menstrual bleeding Genitourinary 1.01 0.941 – 1.08 0.807 970 8996 all phecode
626.15 Infertility, female, associated with anovulation Genitourinary 1.01 0.904 – 1.12 0.896 394 3789 all phecode
626.2 Dysmenorrhea Genitourinary 1.06 1 – 1.13 0.0408 1373 9857 all phecode
626.4 Premenstrual tension syndromes Genitourinary 1.08 0.965 – 1.22 0.176 336 3308 all phecode
626.8 Infertility, female Genitourinary 1.01 0.937 – 1.09 0.776 817 6741 all phecode
627 Menopausal and postmenopausal disorders Genitourinary 0.985 0.951 – 1.02 0.409 4560 14557 all phecode
627.1 Postmenopausal bleeding Genitourinary 0.984 0.923 – 1.05 0.623 1146 10338 all phecode
627.2 Symptomatic menopause Genitourinary 0.976 0.936 – 1.02 0.253 3017 13763 all phecode
627.21 Symptomatic artificial menopause Genitourinary 0.988 0.828 – 1.18 0.898 152 1514 all phecode
627.22
Need for Hormone replacement therapy
Need for Hormone replacement therapy (postmenopausal)
 Genitourinary 0.931 0.828 – 1.05 0.228 356 3513 all phecode
627.3 Postmenopausal atrophic vaginitis Genitourinary 1.02 0.955 – 1.1 0.506 997 9484 all phecode
627.4 Premenopausal menorrhagia Genitourinary 0.95 0.847 – 1.07 0.386 361 3580 all phecode
627.5 Premature menopause and other ovarian failure Genitourinary 0.91 0.805 – 1.03 0.133 309 3082 all phecode
628 Ovarian cyst Genitourinary 1.03 0.979 – 1.08 0.264 1945 13838 all phecode
634 Miscarriage; stillbirth Pregnancy Complications 0.962 0.892 – 1.04 0.315 826 8047 all phecode
634.1 Missed abortion/Hydatidiform mole Pregnancy Complications 0.93 0.817 – 1.06 0.275 273 2715 all phecode
634.3 Ectopic pregnancy Pregnancy Complications 1.07 0.871 – 1.31 0.531 117 1170 all phecode
635
Hemorrhage during pregnancy; childbirth and
Hemorrhage during pregnancy; childbirth and postpartum
 Pregnancy Complications 0.935 0.853 – 1.02 0.149 563 5309 all phecode
635.2
Antepartum hemorrhage, abruptio placentae, and
Antepartum hemorrhage, abruptio placentae, and placenta previa
 Pregnancy Complications 0.925 0.826 – 1.03 0.171 370 3629 all phecode
635.3 Placenta previa and abruptio placenta Pregnancy Complications 0.93 0.819 – 1.06 0.262 288 2850 all phecode
636
Early or threatened labor; hemorrhage in early
Early or threatened labor; hemorrhage in early pregnancy
 Pregnancy Complications 0.959 0.896 – 1.03 0.223 1080 7870 all phecode
636.1 Threatened premature labor Pregnancy Complications 0.954 0.853 – 1.07 0.401 380 3799 all phecode
636.2 Early onset of delivery Pregnancy Complications 0.96 0.845 – 1.09 0.525 288 2868 all phecode
636.3 Hemorrhage in early pregnancy Pregnancy Complications 0.987 0.889 – 1.1 0.808 441 4365 all phecode
636.8 Cervical incompetence Pregnancy Complications 1.3 1.02 – 1.67 0.0377 77 770 all phecode
637
Short gestation; low birth weight; and fetal
Short gestation; low birth weight; and fetal growth retardation
 Pregnancy Complications 0.992 0.786 – 1.25 0.945 85 850 all phecode
642
Hypertension complicating pregnancy
Hypertension complicating pregnancy, childbirth, and the puerperium
 Pregnancy Complications 1.02 0.935 – 1.12 0.631 585 5725 all phecode
642.1 Preeclampsia and eclampsia Pregnancy Complications 0.991 0.873 – 1.13 0.893 302 3013 all phecode
643 Excessive vomiting in pregnancy Pregnancy Complications 0.89 0.775 – 1.02 0.0967 252 2506 all phecode
643.1 Hyperemesis gravidarum Pregnancy Complications 0.861 0.703 – 1.05 0.149 119 1190 all phecode
644 Anemia during pregnancy Pregnancy Complications 0.943 0.816 – 1.09 0.424 224 2224 all phecode
646 Other complications of pregnancy NEC Pregnancy Complications 0.966 0.895 – 1.04 0.373 855 6531 all phecode
647
Infectious and parasitic complications
Infectious and parasitic complications affecting pregnancy
 Pregnancy Complications 0.89 0.767 – 1.03 0.128 211 2093 all phecode
647.1
Infections of genitourinary tract during
Infections of genitourinary tract during pregnancy
 Pregnancy Complications 1.12 0.969 – 1.3 0.123 222 2213 all phecode
647.3 Major puerperal infection Pregnancy Complications 1.02 0.784 – 1.33 0.871 65 650 all phecode
649
Other conditions or status of the mother
Other conditions or status of the mother complicating pregnancy, childbirth, or the puerperium
 Pregnancy Complications 0.934 0.878 – 0.995 0.0341 1275 8010 all phecode
649.1
Diabetes or abnormal glucose tolerance
Diabetes or abnormal glucose tolerance complicating pregnancy
 Pregnancy Complications 1.04 0.95 – 1.13 0.417 649 5687 all phecode
653
Problems associated with amniotic cavity and
Problems associated with amniotic cavity and membranes
 Pregnancy Complications 0.909 0.831 – 0.995 0.0382 587 5463 all phecode
654.1
Abnormality of organs and soft tissues of
Abnormality of organs and soft tissues of pelvis complicating pregnancy, childbirth, or the puerperium
 Pregnancy Complications 0.962 0.828 – 1.12 0.606 207 2055 all phecode
654.2 Rhesus isoimmunization in pregnancy Pregnancy Complications 0.836 0.719 – 0.972 0.0195 204 2040 all phecode
655
Known or suspected fetal abnormality affecting
Known or suspected fetal abnormality affecting management of mother
 Pregnancy Complications 0.964 0.912 – 1.02 0.2 1624 10064 all phecode
655.1 Abnormality in fetal heart rate or rhythm Pregnancy Complications 1 0.92 – 1.1 0.926 616 5533 all phecode
656 Other perinatal conditions of fetus or newborn Pregnancy Complications 0.984 0.915 – 1.06 0.672 898 7014 all phecode
656.2 Respiratory conditions of fetus and newborn Pregnancy Complications 0.926 0.715 – 1.2 0.557 66 660 all phecode
669 Complications of labor and delivery NEC Pregnancy Complications 0.974 0.905 – 1.05 0.486 887 6802 all phecode
671
Venous/cerebrovascular complications embolism
Venous/cerebrovascular complications embolism in pregnancy and the puerperium
 Pregnancy Complications 1.02 0.882 – 1.18 0.799 236 2351 all phecode
674 Other complications of the puerperium NEC Pregnancy Complications 0.982 0.826 – 1.17 0.842 158 1580 all phecode
676
Other disorders of the breast associated with
Other disorders of the breast associated with childbirth and disorders of lactation
 Pregnancy Complications 0.989 0.845 – 1.16 0.893 184 1814 all phecode
681 Superficial cellulitis and abscess Dermatologic 1.05 1.02 – 1.08 0.000797 6500 38394 all phecode
681.1 Cellulitis and abscess of fingers/toes Dermatologic 1.09 1.02 – 1.16 0.00726 1256 11462 all phecode
681.2 Cellulitis and abscess of face/neck Dermatologic 1.05 0.976 – 1.12 0.209 1007 9981 all phecode
681.3 Cellulitis and abscess of arm/hand Dermatologic 1.04 0.99 – 1.09 0.122 2123 19952 all phecode
681.5 Cellulitis and abscess of leg, except foot Dermatologic 1.03 0.983 – 1.08 0.225 2252 20944 all phecode
681.6 Cellulitis and abscess of foot, toe Dermatologic 1.05 0.998 – 1.11 0.0604 1820 16893 all phecode
681.7 Cellulitis and abscess of trunk Dermatologic 1.06 1.01 – 1.12 0.0289 1572 15588 all phecode
686
Other local infections of skin and subcutaneous
Other local infections of skin and subcutaneous tissue
 Dermatologic 1.07 1.02 – 1.12 0.00673 2257 21750 all phecode
686.1 Carbuncle and furuncle Dermatologic 1 0.914 – 1.1 0.961 558 5504 all phecode
686.2 Impetigo Dermatologic 1.01 0.906 – 1.12 0.874 414 4117 all phecode
686.3 Pilonidal cyst Dermatologic 1.07 0.903 – 1.28 0.422 160 1594 all phecode
686.4 Pyogenic granuloma Dermatologic 1.08 0.907 – 1.28 0.399 158 1570 all phecode
686.5 Pyoderma Dermatologic 0.879 0.673 – 1.15 0.342 63 630 all phecode
687 Symptoms affecting skin Dermatologic 1.02 0.964 – 1.07 0.565 1690 16343 all phecode
687.1 Rash and other nonspecific skin eruption Dermatologic 1.01 0.98 – 1.03 0.627 7007 34623 all phecode
687.3 Changes in skin texture Dermatologic 1.08 0.972 – 1.2 0.151 415 4121 all phecode
687.4 Disturbance of skin sensation Dermatologic 1.04 1.01 – 1.07 0.0133 6375 34216 all phecode
689 Disorder of skin and subcutaneous tissue NOS Dermatologic 1.01 0.987 – 1.04 0.361 9311 37335 all phecode
690 Erythematosquamous dermatosis Dermatologic 1.02 0.987 – 1.05 0.244 5184 31581 all phecode
690.1 Seborrheic dermatitis Dermatologic 1.02 0.988 – 1.05 0.228 5174 31553 all phecode
691 Congenital anomalies of skin Dermatologic 0.959 0.874 – 1.05 0.379 541 5337 all phecode
691.3 Congenital pigmentary anomalies of skin Dermatologic 1.07 0.825 – 1.39 0.599 62 613 all phecode
694 Dyschromia and Vitiligo Dermatologic 0.983 0.934 – 1.03 0.496 1861 17936 all phecode
694.1 Vitiligo Dermatologic 0.924 0.772 – 1.1 0.385 137 1347 all phecode
694.2 Other dyschromia Dermatologic 0.972 0.922 – 1.03 0.297 1674 16183 all phecode
694.3 Vascular disorders of skin Dermatologic 1.37 1.08 – 1.75 0.00994 82 819 all phecode
695 Erythematous conditions Dermatologic 0.999 0.966 – 1.03 0.969 4120 30247 all phecode
695.1 Toxic erythema Dermatologic 0.879 0.684 – 1.13 0.311 70 688 all phecode
695.2 Bullous dermatoses Dermatologic 1.04 0.825 – 1.3 0.755 85 805 all phecode
695.3 Rosacea Dermatologic 0.955 0.908 – 1.01 0.0782 1816 17663 all phecode
695.4 Lupus (localized and systemic) Dermatologic 1.05 0.967 – 1.14 0.239 672 6686 all phecode
695.41 Cutaneous lupus erythematosus Dermatologic 1.06 0.923 – 1.22 0.413 247 2437 all phecode
695.42 Systemic lupus erythematosus Dermatologic 1.04 0.954 – 1.13 0.382 637 6337 all phecode
695.7 Prurigo and Lichen Dermatologic 1.04 0.95 – 1.13 0.418 605 5986 all phecode
695.8 Other specified erythematous conditions Dermatologic 0.97 0.899 – 1.05 0.423 812 7980 all phecode
695.81 Erythema nodosum Dermatologic 0.811 0.606 – 1.09 0.16 55 550 all phecode
695.9 Unspecified erythematous condition Dermatologic 1 0.921 – 1.09 0.995 679 6756 all phecode
696 Psoriasis and related disorders Dermatologic 1.05 0.988 – 1.11 0.121 1401 13832 all phecode
696.3 Pityriasis Dermatologic 0.97 0.777 – 1.21 0.79 92 904 all phecode
696.4 Psoriasis Dermatologic 1.06 1 – 1.13 0.0414 1311 12976 all phecode
696.41 Psoriasis vulgaris Dermatologic 1.04 0.978 – 1.11 0.212 1200 11867 all phecode
696.42 Psoriatic arthropathy Dermatologic 1.1 0.97 – 1.25 0.136 282 2810 all phecode
697 Sarcoidosis Dermatologic 1.02 0.909 – 1.15 0.705 333 3330 all phecode
698 Pruritus and related conditions Dermatologic 1 0.958 – 1.05 0.912 2254 21889 all phecode
700 Corns and callosities Dermatologic 1.05 0.992 – 1.12 0.0875 1373 10894 all phecode
701
Other hypertrophic and atrophic conditions of
Other hypertrophic and atrophic conditions of skin
 Dermatologic 1.01 0.986 – 1.04 0.358 7651 38050 all phecode
701.1 Keratoderma, acquired Dermatologic 1.05 0.957 – 1.15 0.313 567 5524 all phecode
701.2 Scar conditions and fibrosis of skin Dermatologic 0.986 0.941 – 1.03 0.541 2184 21550 all phecode
701.3 Circumscribed scleroderma Dermatologic 1.02 0.928 – 1.11 0.739 571 5660 all phecode
701.4 Keloid scar Dermatologic 0.927 0.848 – 1.01 0.0973 578 5716 all phecode
701.5 Abnormal granulation tissue Dermatologic 1.08 0.97 – 1.2 0.162 400 3982 all phecode
702
Degenerative skin conditions and other
Degenerative skin conditions and other dermatoses
 Dermatologic 1.01 0.98 – 1.04 0.58 6956 29525 all phecode
702.1 Actinic keratosis Dermatologic 0.996 0.962 – 1.03 0.84 4171 26529 all phecode
702.2 Seborrheic keratosis Dermatologic 1 0.972 – 1.03 0.867 5480 31552 all phecode
702.4 Degenerative skin disorders Dermatologic 0.837 0.66 – 1.06 0.141 86 832 all phecode
703 Diseases of nail, NOS Dermatologic 0.993 0.941 – 1.05 0.798 1650 14562 all phecode
703.1 Ingrowing nail Dermatologic 1.04 0.973 – 1.12 0.232 920 8597 all phecode
704 Diseases of hair and hair follicles Dermatologic 1.04 0.999 – 1.08 0.0559 3118 29542 all phecode
704.1 Alopecia Dermatologic 1.06 1 – 1.13 0.0406 1408 13871 all phecode
704.11 Alopecia Areata Dermatologic 1.03 0.814 – 1.3 0.806 82 811 all phecode
704.12 Telogen effluvium Dermatologic 0.904 0.684 – 1.19 0.476 63 615 all phecode
704.2 Hirsutism Dermatologic 1.1 0.971 – 1.25 0.135 299 2946 all phecode
704.8
Other specified diseases of hair and hair
Other specified diseases of hair and hair follicles
 Dermatologic 1.02 0.97 – 1.08 0.412 1752 17189 all phecode
705 Disorders of sweat glands Dermatologic 1.07 0.976 – 1.16 0.158 603 6012 all phecode
705.1 Dyshidrosis Dermatologic 0.959 0.805 – 1.14 0.642 154 1540 all phecode
705.3 Hidradenitis Dermatologic 1.15 0.998 – 1.32 0.0542 245 2440 all phecode
705.8 Hyperhidrosis Dermatologic 1.04 0.97 – 1.11 0.288 1112 10986 all phecode
706 Diseases of sebaceous glands Dermatologic 1.02 0.99 – 1.05 0.196 5995 39748 all phecode
706.1 Acne Dermatologic 0.99 0.949 – 1.03 0.651 2594 22570 all phecode
706.2 Sebaceous cyst Dermatologic 1.04 0.997 – 1.08 0.0701 2814 26819 all phecode
706.3 Seborrhea Dermatologic 1.38 1.05 – 1.81 0.022 59 582 all phecode
706.8 Other specified diseases of sebaceous glands Dermatologic 1.03 0.975 – 1.09 0.295 1684 15289 all phecode
707 Chronic ulcer of skin Dermatologic 1.05 1.01 – 1.1 0.0115 2871 26816 all phecode
707.1 Decubitus ulcer Dermatologic 1.03 0.953 – 1.11 0.491 825 8119 all phecode
707.2 Chronic ulcer of leg or foot Dermatologic 1.08 1.02 – 1.16 0.0148 1108 9992 all phecode
707.3 Chronic ulcer of unspecified site Dermatologic 1.05 0.997 – 1.11 0.0625 1641 16172 all phecode
709 Diffuse diseases of connective tissue Dermatologic 0.993 0.939 – 1.05 0.82 1477 14427 all phecode
709.2 Sicca syndrome Dermatologic 0.977 0.886 – 1.08 0.634 505 4986 all phecode
709.3 Systemic sclerosis Dermatologic 0.982 0.85 – 1.13 0.802 224 2209 all phecode
709.5 Dermatomyositis Dermatologic 0.91 0.728 – 1.14 0.409 92 892 all phecode
709.6
Other specified diffuse diseases of connective
Other specified diffuse diseases of connective tissue
 Dermatologic 0.927 0.741 – 1.16 0.508 90 892 all phecode
709.7 Unspecified diffuse connective tissue disease Dermatologic 0.988 0.92 – 1.06 0.75 917 9089 all phecode
710
Osteomyelitis, periostitis, and other
Osteomyelitis, periostitis, and other infections involving bone
 Musculoskeletal 1.1 1.04 – 1.17 0.00157 1254 12103 all phecode
710.1 Osteomyelitis Musculoskeletal 1.11 1.04 – 1.18 0.00145 1203 11636 all phecode
710.11 Acute osteomyelitis Musculoskeletal 1.19 1.09 – 1.3 0.00016 590 5708 all phecode
710.12 Chronic osteomyelitis Musculoskeletal 1.06 0.967 – 1.16 0.213 531 5163 all phecode
710.19 Unspecified osteomyelitis Musculoskeletal 1.1 1.03 – 1.17 0.00323 1153 11149 all phecode
711 Arthropathy associated with infections Musculoskeletal 1.01 0.906 – 1.13 0.859 410 4099 all phecode
711.1 Pyogenic arthritis Musculoskeletal 1.02 0.896 – 1.16 0.773 290 2900 all phecode
712 Infective connective tissue disorders Musculoskeletal 0.964 0.819 – 1.14 0.661 178 1776 all phecode
713
Arthropathy associated with other disorders
Arthropathy associated with other disorders classified elsewhere
 Musculoskeletal 1.04 0.921 – 1.17 0.537 314 3028 all phecode
713.5
Arthropathy associated with neurological
Arthropathy associated with neurological disorders
 Musculoskeletal 1.02 0.879 – 1.2 0.754 194 1824 all phecode
714
Rheumatoid arthritis and other inflammatory
Rheumatoid arthritis and other inflammatory polyarthropathies
 Musculoskeletal 1.05 1 – 1.1 0.05 2086 18159 all phecode
714.1 Rheumatoid arthritis Musculoskeletal 1.06 1 – 1.12 0.0368 1670 15087 all phecode
714.2 Juvenile rheumatoid arthritis Musculoskeletal 1.01 0.79 – 1.3 0.928 77 767 all phecode
715 Other inflammatory spondylopathies Musculoskeletal 1.03 0.972 – 1.1 0.285 1209 11967 all phecode
715.1 Sacroiliitis NEC Musculoskeletal 1.05 0.917 – 1.2 0.483 262 2611 all phecode
715.2 Ankylosing spondylitis Musculoskeletal 1 0.864 – 1.16 0.99 219 2182 all phecode
716 Other arthropathies Musculoskeletal 1.04 1.01 – 1.06 0.00148 13482 31305 all phecode
716.1 Unspecified polyarthropathy or polyarthritis Musculoskeletal 1.04 0.882 – 1.22 0.671 192 1920 all phecode
716.2 Unspecified monoarthritis Musculoskeletal 0.878 0.725 – 1.06 0.185 131 1293 all phecode
716.9 Arthropathy NOS Musculoskeletal 1.04 1.01 – 1.06 0.00146 13410 31294 all phecode
717 Polymyalgia Rheumatica Musculoskeletal 1.1 0.96 – 1.26 0.172 261 2565 all phecode
720 Spinal stenosis Musculoskeletal 1.03 0.997 – 1.07 0.0689 3958 28539 all phecode
720.1 Spinal stenosis of lumbar region Musculoskeletal 1.04 0.994 – 1.08 0.0909 2872 23656 all phecode
721 Spondylosis and allied disorders Musculoskeletal 1.03 0.996 – 1.06 0.0884 5509 32391 all phecode
721.1 Spondylosis without myelopathy Musculoskeletal 1.03 0.998 – 1.06 0.0674 5153 31896 all phecode
721.2 Spondylosis with myelopathy Musculoskeletal 1.03 0.955 – 1.11 0.454 867 8629 all phecode
721.8 Other allied disorders of spine Musculoskeletal 1.04 0.911 – 1.19 0.562 262 2600 all phecode
722 Intervertebral disc disorders Musculoskeletal 1.03 1 – 1.06 0.0529 6284 34317 all phecode
722.1 Displacement of intervertebral disc Musculoskeletal 1.04 1 – 1.08 0.0458 3591 31411 all phecode
722.3 Schmorl's nodes Musculoskeletal 1.12 0.924 – 1.35 0.253 126 1248 all phecode
722.6 Degeneration of intervertebral disc Musculoskeletal 1.01 0.98 – 1.05 0.408 3957 30744 all phecode
722.7 Intervertebral disc disorder with myelopathy Musculoskeletal 1.04 0.944 – 1.14 0.428 515 5140 all phecode
722.8 Postlaminectomy syndrome Musculoskeletal 1.14 1.03 – 1.27 0.0157 397 3968 all phecode
722.9 Other and unspecified disc disorder Musculoskeletal 1.05 1 – 1.1 0.0439 1932 19288 all phecode
723 Other disorders of cervical region Musculoskeletal 1.04 0.974 – 1.12 0.223 952 9495 all phecode
723.1 Torticollis Musculoskeletal 1.08 0.944 – 1.24 0.256 254 2522 all phecode
724 Other and unspecified disorders of back Musculoskeletal 1.02 0.985 – 1.06 0.264 4130 31954 all phecode
724.1 Disorders of sacrum Musculoskeletal 1.01 0.966 – 1.06 0.655 2307 21902 all phecode
724.2 Disorders of coccyx Musculoskeletal 0.934 0.841 – 1.04 0.202 426 4215 all phecode
724.8 Other symptoms referable to back Musculoskeletal 0.962 0.896 – 1.03 0.287 931 9295 all phecode
724.9 Other unspecified back disorders Musculoskeletal 1.06 0.998 – 1.12 0.0589 1412 14087 all phecode
726 Peripheral enthesopathies and allied syndromes Musculoskeletal 0.999 0.975 – 1.02 0.904 9917 30176 all phecode
726.1 Enthesopathy Musculoskeletal 1 0.975 – 1.03 0.919 7507 30106 all phecode
726.2 Synoviopathy Musculoskeletal 1.03 0.961 – 1.1 0.426 1015 9987 all phecode
726.3 Bursitis Musculoskeletal 0.981 0.932 – 1.03 0.46 1829 16722 all phecode
726.4 Calcaneal spur; Exostosis NOS Musculoskeletal 0.983 0.923 – 1.05 0.599 1193 11485 all phecode
727 Other disorders of synovium, tendon, and bursa Musculoskeletal 0.997 0.971 – 1.02 0.838 7425 30105 all phecode
727.1 Synovitis and tenosynovitis Musculoskeletal 1.02 0.977 – 1.06 0.405 3092 24998 all phecode
727.2 Bursitis disorders Musculoskeletal 0.92 0.828 – 1.02 0.121 419 4112 all phecode
727.4 Ganglion and cyst of synovium, tendon, and bursa Musculoskeletal 0.969 0.914 – 1.03 0.292 1400 13621 all phecode
727.5 Rupture of synovium Musculoskeletal 1.02 0.925 – 1.13 0.657 480 4672 all phecode
727.6 Rupture of tendon, nontraumatic Musculoskeletal 1.01 0.971 – 1.06 0.522 2461 21948 all phecode
727.7 Contracture of tendon (sheath) Musculoskeletal 0.968 0.886 – 1.06 0.466 591 5893 all phecode
727.8 Plica syndrome Musculoskeletal 0.951 0.784 – 1.15 0.606 130 1264 all phecode
728 Disorders of muscle, ligament, and fascia Musculoskeletal 1.01 0.975 – 1.04 0.669 4546 29473 all phecode
728.1 Muscular calcification and ossification Musculoskeletal 1.04 0.817 – 1.33 0.745 85 843 all phecode
728.2 Laxity of ligament or hypermobility syndrome Musculoskeletal 0.997 0.88 – 1.13 0.962 297 2949 all phecode
728.7 Fasciitis Musculoskeletal 0.962 0.923 – 1 0.0678 2814 23463 all phecode
728.71
Contracture of palmar fascia [Dupuytren's
Contracture of palmar fascia [Dupuytren's disease]
 Musculoskeletal 0.952 0.858 – 1.06 0.353 419 4138 all phecode
729 Other disorders of soft tissues Musculoskeletal 1.02 0.984 – 1.06 0.266 3642 27471 all phecode
729.1 Rheumatism, unspecified and fibrositis Musculoskeletal 1.03 0.808 – 1.32 0.797 74 726 all phecode
729.3 Panniculitis Musculoskeletal 0.876 0.716 – 1.07 0.194 119 1174 all phecode
729.7 Nontraumatic compartment syndrome Musculoskeletal 1.1 0.846 – 1.42 0.488 67 664 all phecode
731
Osteitis deformans and osteopathies associated
Osteitis deformans and osteopathies associated with other disorders classified elsewhere
 Musculoskeletal 1.01 0.867 – 1.17 0.936 210 2091 all phecode
732 Osteochondropathies Musculoskeletal 1.06 0.942 – 1.18 0.351 361 3604 all phecode
732.1 Juvenile osteochondrosis Musculoskeletal 1.04 0.895 – 1.22 0.582 198 1969 all phecode
732.7 Osteochondritis dissecans Musculoskeletal 1.08 0.862 – 1.35 0.503 90 882 all phecode
733 Other disorders of bone and cartilage Musculoskeletal 0.985 0.953 – 1.02 0.389 4543 26941 all phecode
733.2 Cyst of bone Musculoskeletal 0.904 0.773 – 1.06 0.202 190 1900 all phecode
733.4 Aseptic necrosis of bone Musculoskeletal 0.997 0.907 – 1.1 0.953 518 5160 all phecode
733.6 Costochondritis Musculoskeletal 0.959 0.854 – 1.08 0.485 357 3562 all phecode
733.8 Malunion and nonunion of fracture Musculoskeletal 1.03 0.955 – 1.11 0.45 822 8205 all phecode
733.9 Chondromalacia Musculoskeletal 1.05 0.847 – 1.31 0.637 96 960 all phecode
735 Acquired foot deformities Musculoskeletal 0.996 0.959 – 1.03 0.835 3417 29622 all phecode
735.1 Flat foot Musculoskeletal 0.935 0.857 – 1.02 0.125 620 6092 all phecode
735.2 Acquired toe deformities Musculoskeletal 1.05 0.994 – 1.12 0.0781 1323 11983 all phecode
735.21 Hammer toe (acquired) Musculoskeletal 1.02 0.95 – 1.1 0.543 825 7494 all phecode
735.23 Hallux rigidus Musculoskeletal 1.15 1.03 – 1.28 0.0109 405 4005 all phecode
735.3 Hallux valgus (Bunion) Musculoskeletal 0.958 0.906 – 1.01 0.133 1470 14295 all phecode
736 Other acquired deformities of limbs Musculoskeletal 0.963 0.924 – 1 0.0758 2763 26555 all phecode
736.1 Acquired deformities of forearm Musculoskeletal 1.07 0.871 – 1.32 0.508 104 1033 all phecode
736.2 Acquired deformities of finger Musculoskeletal 1.11 0.962 – 1.29 0.15 215 2142 all phecode
736.3 Acquired deformities of hip Musculoskeletal 1.13 0.861 – 1.49 0.369 60 590 all phecode
736.4 Genu valgum or varum (acquired) Musculoskeletal 0.87 0.772 – 0.981 0.0235 325 3247 all phecode
736.5 Acquired deformities of knee Musculoskeletal 0.947 0.823 – 1.09 0.452 246 2460 all phecode
736.6 Unequal leg length (acquired) Musculoskeletal 0.887 0.787 – 1 0.0511 339 3365 all phecode
737 Curvature of spine Musculoskeletal 0.97 0.919 – 1.02 0.28 1566 15543 all phecode
737.1 Kyphosis (acquired) Musculoskeletal 0.967 0.877 – 1.07 0.508 479 4748 all phecode
737.2 Lordosis (acquired) Musculoskeletal 1.01 0.775 – 1.31 0.949 70 700 all phecode
737.3 Kyphoscoliosis and scoliosis Musculoskeletal 0.954 0.896 – 1.02 0.143 1203 11982 all phecode
738 Other acquired musculoskeletal deformity Musculoskeletal 0.99 0.948 – 1.04 0.67 2443 24187 all phecode
738.4 Acquired spondylolisthesis Musculoskeletal 1 0.937 – 1.07 0.955 1057 10542 all phecode
739 Contracture of joint Musculoskeletal 0.946 0.868 – 1.03 0.212 621 6207 all phecode
740 Osteoarthrosis Musculoskeletal 1.03 1 – 1.05 0.0196 16169 30268 all phecode
740.1 Osteoarthritis; localized Musculoskeletal 0.993 0.965 – 1.02 0.623 7005 27422 all phecode
740.11 Osteoarthrosis, localized, primary Musculoskeletal 0.985 0.956 – 1.01 0.321 6176 26155 all phecode
740.12 Osteoarthrosis, localized, secondary Musculoskeletal 0.996 0.919 – 1.08 0.931 713 7116 all phecode
740.2 Osteoarthrosis, generalized Musculoskeletal 1.02 0.965 – 1.08 0.488 1609 12092 all phecode
740.3
Osteoarthrosis involving more than one site
Osteoarthrosis involving more than one site, but not specified as generalized
 Musculoskeletal 1.09 0.973 – 1.21 0.14 373 3586 all phecode
740.9 Osteoarthrosis NOS Musculoskeletal 1.03 1.01 – 1.05 0.01 15497 30141 all phecode
741 Symptoms and disorders of the joints Musculoskeletal 1.01 0.989 – 1.04 0.264 8555 35884 all phecode
741.1 Ankylosis of joint Musculoskeletal 1.02 0.889 – 1.17 0.776 245 2445 all phecode
741.2 Stiffness of joint Musculoskeletal 1.01 0.947 – 1.07 0.818 1268 12594 all phecode
741.3 Difficulty in walking Musculoskeletal 1.05 1.01 – 1.1 0.0254 2558 23116 all phecode
741.4 Joint effusions Musculoskeletal 0.994 0.952 – 1.04 0.784 2493 24199 all phecode
741.5 Hemarthrosis Musculoskeletal 0.993 0.797 – 1.24 0.948 94 937 all phecode
741.6 Villonodular synovitis Musculoskeletal 0.918 0.709 – 1.19 0.52 68 666 all phecode
742 Derangement of joint, non-traumatic Musculoskeletal 0.999 0.967 – 1.03 0.962 4404 33771 all phecode
742.1 Loose body in joint Musculoskeletal 1.06 0.895 – 1.26 0.487 156 1554 all phecode
742.2
Pathological, developmental or recurrent
Pathological, developmental or recurrent dislocation
 Musculoskeletal 0.882 0.775 – 1 0.0591 280 2792 all phecode
742.8 Articular cartilage disorder Musculoskeletal 0.95 0.829 – 1.09 0.459 245 2450 all phecode
742.9 Other derangement of joint Musculoskeletal 1 0.968 – 1.04 0.923 4107 32972 all phecode
743
Osteoporosis, osteopenia and pathological
Osteoporosis, osteopenia and pathological fracture
 Musculoskeletal 0.975 0.951 – 1 0.0487 9223 36921 all phecode
743.1 Osteoporosis Musculoskeletal 0.971 0.934 – 1.01 0.127 3712 19477 all phecode
743.11 Osteoporosis NOS Musculoskeletal 0.972 0.935 – 1.01 0.147 3657 19276 all phecode
743.12 Senile osteoporosis Musculoskeletal 0.906 0.833 – 0.984 0.0195 703 5804 all phecode
743.13 Other specified osteoporosis Musculoskeletal 0.936 0.83 – 1.06 0.287 321 3141 all phecode
743.2 Pathologic fracture Musculoskeletal 0.983 0.921 – 1.05 0.599 1112 10563 all phecode
743.21 Pathologic fracture of vertebrae Musculoskeletal 1.03 0.932 – 1.13 0.577 475 4629 all phecode
743.22 Pathologic fracture of femur Musculoskeletal 1.05 0.874 – 1.26 0.604 143 1391 all phecode
743.4 Stress fracture Musculoskeletal 1 0.902 – 1.12 0.94 407 4046 all phecode
743.9
Osteopenia or other disorder of bone and
Osteopenia or other disorder of bone and cartilage
 Musculoskeletal 0.965 0.939 – 0.993 0.0133 6970 35237 all phecode
745 Pain in joint Musculoskeletal 0.999 0.979 – 1.02 0.879 19848 26918 all phecode
747 Cardiac and circulatory congenital anomalies Congenital Anomalies 1.01 0.961 – 1.05 0.795 2236 22256 all phecode
747.1 Cardiac congenital anomalies Congenital Anomalies 1 0.954 – 1.06 0.867 1767 17598 all phecode
747.11 Cardiac shunt/ heart septal defect Congenital Anomalies 0.982 0.902 – 1.07 0.681 650 6497 all phecode
747.12 Valvular heart disease/ heart chambers Congenital Anomalies 1.02 0.943 – 1.11 0.604 751 7480 all phecode
747.13 Congenital anomalies of great vessels Congenital Anomalies 1.05 0.944 – 1.17 0.372 410 4090 all phecode
747.2
Congenital anomalies of peripheral vascular
Congenital anomalies of peripheral vascular system
 Congenital Anomalies 1.02 0.922 – 1.12 0.748 501 5010 all phecode
748 Anomalies of respiratory system, congenital Congenital Anomalies 1.05 0.853 – 1.29 0.65 111 1110 all phecode
749 Congenital anomalies of face and neck Congenital Anomalies 0.985 0.899 – 1.08 0.754 555 5549 all phecode
749.1 Cleft palate Congenital Anomalies 1.03 0.832 – 1.27 0.803 97 970 all phecode
749.2 Congenital anomalies of skull and face bones Congenital Anomalies 1.11 0.903 – 1.36 0.325 105 1041 all phecode
750 Digestive congenital anomalies Congenital Anomalies 1.01 0.943 – 1.09 0.705 893 8919 all phecode
750.1 Upper gastrointestinal congenital anomalies Congenital Anomalies 1.06 0.942 – 1.18 0.351 366 3655 all phecode
750.11 Esophageal atresia/tracheoesophageal fistula Congenital Anomalies 1.05 0.862 – 1.28 0.623 119 1185 all phecode
750.13 Congenital anomalies of mouth/tongue Congenital Anomalies 0.903 0.732 – 1.11 0.338 99 982 all phecode
750.14 Congenital anomalies of esophagus Congenital Anomalies 1.15 0.958 – 1.39 0.134 134 1332 all phecode
750.15 Congenital anomalies of stomach Congenital Anomalies 1.35 1.02 – 1.78 0.0386 60 593 all phecode
750.2 Lower gastrointestinal congenital anomalies Congenital Anomalies 0.969 0.882 – 1.07 0.517 531 5300 all phecode
750.21 Congenital anomalies of intestine Congenital Anomalies 0.957 0.847 – 1.08 0.476 313 3129 all phecode
750.22
Congenital anomaly of gallbladder, bile ducts
Congenital anomaly of gallbladder, bile ducts, liver, pancreas
 Congenital Anomalies 1.06 0.918 – 1.23 0.414 222 2214 all phecode
751 Genitourinary congenital anomalies Congenital Anomalies 1.01 0.959 – 1.06 0.793 2008 19975 all phecode
751.1 Congenital anomalies of genital organs Congenital Anomalies 0.976 0.892 – 1.07 0.594 574 5740 all phecode
751.11 Congenital anomalies of female genital organs Congenital Anomalies 0.992 0.888 – 1.11 0.89 384 3840 all phecode
751.12 Congenital anomalies of male genital organs Congenital Anomalies 0.973 0.822 – 1.15 0.748 153 1527 all phecode
751.2 Congenital anomalies of urinary system Congenital Anomalies 1 0.946 – 1.06 0.93 1379 13704 all phecode
751.21 Cystic kidney disease Congenital Anomalies 0.986 0.92 – 1.06 0.68 976 9685 all phecode
751.22 Other specified congenital anomalies of kidney Congenital Anomalies 1.07 0.943 – 1.21 0.294 294 2927 all phecode
751.3 Obstructive genitourinary defect Congenital Anomalies 0.98 0.837 – 1.15 0.801 182 1809 all phecode
752 Nervous system congenital anomalies Congenital Anomalies 1.01 0.943 – 1.07 0.847 1133 11313 all phecode
752.1 Neural tube defects Congenital Anomalies 1.02 0.948 – 1.09 0.626 923 9209 all phecode
752.11 Spina bifida Congenital Anomalies 0.912 0.776 – 1.07 0.264 176 1760 all phecode
752.2
Other specified congenital anomalies of nervous
Other specified congenital anomalies of nervous system
 Congenital Anomalies 1.05 0.906 – 1.21 0.534 232 2320 all phecode
753 Congenital anomalies of the eye Congenital Anomalies 1.04 0.894 – 1.2 0.623 207 2051 all phecode
753.1 Congenital cataract and lens anomalies Congenital Anomalies 1.09 0.838 – 1.43 0.506 58 580 all phecode
753.2 Congenital anomalies of posterior segment of eye Congenital Anomalies 1 0.742 – 1.36 0.977 56 546 all phecode
754 Congenital musculoskeletal deformities of spine Congenital Anomalies 1.03 0.97 – 1.1 0.315 1216 12116 all phecode
754.1 Lumbosacral spondylolysis, congenital Congenital Anomalies 0.929 0.775 – 1.11 0.427 135 1333 all phecode
754.2 Spondylolisthesis, congenital Congenital Anomalies 1 0.916 – 1.1 0.943 558 5570 all phecode
755 Congenital anomalies of limbs Congenital Anomalies 0.989 0.914 – 1.07 0.79 747 7458 all phecode
755.1 Congenital deformities of feet Congenital Anomalies 1.03 0.923 – 1.16 0.572 368 3663 all phecode
755.4
Congenital anomalies of upper limb, including
Congenital anomalies of upper limb, including shoulder girdle
 Congenital Anomalies 0.846 0.66 – 1.09 0.19 74 740 all phecode
755.6
Other congenital anomalies of lower limb
Other congenital anomalies of lower limb, including pelvic girdle
 Congenital Anomalies 0.959 0.851 – 1.08 0.494 321 3205 all phecode
755.61 Congenital hip dysplasia and deformity Congenital Anomalies 0.945 0.805 – 1.11 0.488 185 1847 all phecode
756 Other congenital musculoskeletal anomalies Congenital Anomalies 0.962 0.907 – 1.02 0.199 1358 13579 all phecode
756.1 Congenital anomalies of abdominal wall; diaphram Congenital Anomalies 0.977 0.744 – 1.28 0.866 68 680 all phecode
756.2
Pectus and other congenital anomalies of
Pectus and other congenital anomalies of ribs/sternum
 Congenital Anomalies 0.868 0.669 – 1.13 0.286 71 694 all phecode
756.3
Congenital anomalies of muscle, tendon, fascia
Congenital anomalies of muscle, tendon, fascia, and connective tissue
 Congenital Anomalies 0.932 0.827 – 1.05 0.242 335 3346 all phecode
756.5 Congenital osteodystrophies Congenital Anomalies 0.981 0.915 – 1.05 0.577 1003 10014 all phecode
757 Congenital anomalies of the integument Congenital Anomalies 1.08 0.973 – 1.21 0.142 401 4001 all phecode
758 Chromosomal anomalies and genetic disorders Congenital Anomalies 0.892 0.761 – 1.04 0.156 185 1845 all phecode
758.1 Chromosomal anomalies Congenital Anomalies 0.91 0.757 – 1.09 0.314 135 1349 all phecode
759 Other and unspecified congenital anomalies Congenital Anomalies 0.972 0.885 – 1.07 0.548 557 5566 all phecode
759.1 Anomalies of endocrine glands, congenital Congenital Anomalies 1.16 0.897 – 1.5 0.256 71 710 all phecode
760 Back pain Symptoms 1.04 1.02 – 1.06 0.000168 16037 30719 all phecode
761 Cervicalgia Symptoms 1.04 1.01 – 1.07 0.00526 6528 39755 all phecode
763
Thoracic or lumbosacral neuritis or
Thoracic or lumbosacral neuritis or radiculitis, unspecified
 Symptoms 1.03 0.996 – 1.07 0.0858 3657 32599 all phecode
764 Sciatica Symptoms 1.04 1 – 1.08 0.0454 3542 32015 all phecode
765 Cervical radiculitis Symptoms 1.03 0.978 – 1.08 0.273 1799 17851 all phecode
766 Neuralgia, neuritis, and radiculitis NOS Symptoms 1.03 1 – 1.07 0.032 5124 37132 all phecode
767 Cervicocranial/Cervicobrachial syndrome Symptoms 1.23 0.997 – 1.51 0.0529 117 1168 all phecode
769 Nonallopathic lesions NEC Symptoms 1.03 0.964 – 1.1 0.388 1131 11220 all phecode
770 Myalgia and myositis unspecified Symptoms 1.04 1.01 – 1.08 0.00476 5533 34303 all phecode
771 Musculoskeletal symptoms referable to limbs Symptoms 1.02 0.987 – 1.05 0.247 4799 35575 all phecode
771.1 Swelling of limb Symptoms 1 0.975 – 1.03 0.766 5743 35539 all phecode
771.2 Cramp of limb Symptoms 1.08 1.01 – 1.16 0.0184 1079 10568 all phecode
772 Symptoms of the muscles Symptoms 0.948 0.904 – 0.995 0.0296 2042 20221 all phecode
772.1 Muscular wasting and disuse atrophy Symptoms 1.01 0.905 – 1.12 0.915 422 4199 all phecode
772.2 Spasm of muscle Symptoms 0.973 0.93 – 1.02 0.231 2299 22726 all phecode
772.3 Muscle weakness Symptoms 1.04 1 – 1.09 0.0379 2949 28064 all phecode
772.4 Rhabdomyolysis Symptoms 1.01 0.849 – 1.19 0.932 159 1572 all phecode
772.6 Facial weakness Symptoms 1.04 0.942 – 1.15 0.441 478 4742 all phecode
780 Hypothermia/Chills Symptoms 1.08 0.976 – 1.19 0.135 453 4514 all phecode
781
Symptoms involving nervous and musculoskeletal
Symptoms involving nervous and musculoskeletal systems
 Symptoms 1.04 0.998 – 1.08 0.0645 2822 26225 all phecode
781.1 Loss of height Symptoms 0.975 0.811 – 1.17 0.792 130 1269 all phecode
781.2 Abnormal posture Symptoms 1.04 0.795 – 1.36 0.768 57 567 all phecode
782.3 Edema Symptoms 1.04 1.01 – 1.07 0.0167 5874 36788 all phecode
782.6 Pallor and flushing Symptoms 0.979 0.911 – 1.05 0.557 927 9252 all phecode
783 Fever of unknown origin Symptoms 1.04 1.01 – 1.08 0.00355 5733 40720 all phecode
783.1 Postprocedural fever Symptoms 1.03 0.906 – 1.16 0.679 300 2992 all phecode
785 Abdominal pain Symptoms 1.04 1.02 – 1.06 0.000437 16458 30297 all phecode
788 Syncope and collapse Symptoms 1 0.969 – 1.04 0.844 3851 35832 all phecode
789 Nausea and vomiting Symptoms 1.04 1.02 – 1.06 0.00107 10568 36098 all phecode
789.1 Persistent vomiting Symptoms 1.09 1.01 – 1.18 0.0227 798 7924 all phecode
790 Nonspecific findings on examination of blood Symptoms 1.06 1.02 – 1.11 0.00896 2363 22690 all phecode
790.1 Elevated sedimentation rate Symptoms 1.12 0.969 – 1.29 0.128 236 2322 all phecode
790.6 Other abnormal blood chemistry Symptoms 1.06 1.04 – 1.09 3.89e-06 7539 37788 all phecode
790.8 Elevated C-reactive protein (CRP) Symptoms 1.14 1.01 – 1.28 0.0387 309 3075 all phecode
790.9 Abnormal arterial blood gases Symptoms 1.01 0.854 – 1.2 0.882 155 1521 all phecode
791 Gangrene Symptoms 1.03 0.916 – 1.17 0.592 313 3115 all phecode
792
Abnormal Papanicolaou smear of cervix and
Abnormal Papanicolaou smear of cervix and cervical HPV
 Genitourinary 1.01 0.972 – 1.06 0.532 2820 14872 all phecode
792.1
Papanicolaou smear of cervix or vagina with
Papanicolaou smear of cervix or vagina with atypical squamous cells
 Genitourinary 1.04 0.974 – 1.11 0.247 1100 9861 all phecode
794
Abnormal results of other function studies
Abnormal results of other function studies (bladder, pancreas, placenta, spleen, etc)
 Symptoms 0.947 0.861 – 1.04 0.267 515 5133 all phecode
795
Other and nonspecific abnormal cytological
Other and nonspecific abnormal cytological, histological and immunological findings
 Symptoms 1.01 0.968 – 1.06 0.563 2182 20242 all phecode
795.8 Abnormal tumor markers Symptoms 0.987 0.937 – 1.04 0.636 1745 15551 all phecode
795.81 Elevated carcinoembryonic antigen [CEA] Symptoms 1.24 0.94 – 1.63 0.129 61 605 all phecode
795.82 Elevated cancer antigen 125 [CA 125] Symptoms 0.917 0.791 – 1.06 0.256 201 2000 all phecode
796 Elevated prostate specific antigen [PSA] Genitourinary 0.973 0.925 – 1.02 0.287 2125 9930 all phecode
797 Shock Symptoms 1.09 0.995 – 1.18 0.0635 605 6050 all phecode
797.1 Cardiogenic shock Symptoms 1.1 0.959 – 1.26 0.171 242 2420 all phecode
798 Malaise and fatigue Symptoms 1.03 1.01 – 1.05 0.0135 11539 35196 all phecode
798.1 Chronic fatigue syndrome Symptoms 1.02 0.966 – 1.07 0.544 1823 17795 all phecode
800 Fracture of lower limb Injuries & Poisonings 1.01 0.963 – 1.05 0.767 2344 22951 all phecode
800.1 Fracture of neck of femur Injuries & Poisonings 1.03 0.938 – 1.13 0.524 512 4961 all phecode
800.2 Fracture of unspecified part of femur Injuries & Poisonings 1.05 0.964 – 1.14 0.269 670 6582 all phecode
800.3 Fracture of tibia and fibula Injuries & Poisonings 1.03 0.955 – 1.1 0.486 898 8966 all phecode
800.4 Fracture of patella Injuries & Poisonings 0.889 0.79 – 0.999 0.0486 346 3456 all phecode
801 Fracture of ankle and foot Injuries & Poisonings 0.984 0.941 – 1.03 0.479 2358 22645 all phecode
801.1 Fracture of foot Injuries & Poisonings 1.02 0.957 – 1.09 0.527 1120 11178 all phecode
802 Fracture of pelvis Injuries & Poisonings 0.953 0.854 – 1.06 0.393 380 3765 all phecode
803 Fracture of upper limb Injuries & Poisonings 0.957 0.912 – 1 0.0727 2051 20360 all phecode
803.1 Fracture of humerus Injuries & Poisonings 0.944 0.872 – 1.02 0.157 734 7322 all phecode
803.2 Fracture of radius and ulna Injuries & Poisonings 0.979 0.917 – 1.04 0.517 1112 11075 all phecode
803.21 Colles' fracture Injuries & Poisonings 0.968 0.852 – 1.1 0.611 291 2904 all phecode
803.3 Fracture of clavicle or scapula Injuries & Poisonings 0.903 0.82 – 0.994 0.0366 514 5140 all phecode
804 Fracture of hand or wrist Injuries & Poisonings 0.954 0.904 – 1.01 0.0852 1628 16042 all phecode
805
Fracture of vertebral column without mention of
Fracture of vertebral column without mention of spinal cord injury
 Injuries & Poisonings 1.02 0.961 – 1.08 0.521 1336 13242 all phecode
807 Fracture of ribs Injuries & Poisonings 1.01 0.931 – 1.1 0.805 683 6815 all phecode
809 Fracture of unspecified bones Injuries & Poisonings 1 0.962 – 1.04 0.969 2941 28633 all phecode
816 Cerebral laceration and contusion Injuries & Poisonings 1.21 0.896 – 1.62 0.217 54 531 all phecode
817 Concussion Injuries & Poisonings 1.05 0.981 – 1.12 0.159 1018 10149 all phecode
818 Intracranial hemorrhage (injury) Injuries & Poisonings 1.06 0.937 – 1.2 0.362 311 3104 all phecode
818.1 Subdural hemorrhage (injury) Injuries & Poisonings 1.2 0.962 – 1.49 0.106 90 895 all phecode
818.2 Subarachnoid hemorrhage (injury) Injuries & Poisonings 1.39 1.11 – 1.73 0.00373 97 970 all phecode
819
Skull and face fracture and other intercranial
Skull and face fracture and other intercranial injury
 Injuries & Poisonings 1.07 1.02 – 1.12 0.00499 2287 22671 all phecode
830 Dislocation Injuries & Poisonings 1 0.969 – 1.04 0.846 3862 34720 all phecode
835 Internal derangement of knee Injuries & Poisonings 0.998 0.953 – 1.05 0.944 2231 21628 all phecode
836 Traumatic arthropathy Injuries & Poisonings 1.06 0.959 – 1.17 0.262 496 4954 all phecode
840 Sprains and strains Injuries & Poisonings 0.985 0.96 – 1.01 0.247 7838 37998 all phecode
840.1 Muscle/tendon sprain Injuries & Poisonings 0.97 0.883 – 1.07 0.528 537 5356 all phecode
840.2 Rotator cuff (capsule) sprain Injuries & Poisonings 1.02 0.97 – 1.08 0.405 1640 16263 all phecode
840.3 Joint/ligament sprain Injuries & Poisonings 0.969 0.931 – 1.01 0.135 2875 24879 all phecode
841 Sprains and strains of back and neck Injuries & Poisonings 0.977 0.925 – 1.03 0.412 1583 15592 all phecode
842 Other sprains and strains Injuries & Poisonings 0.971 0.916 – 1.03 0.317 1407 13924 all phecode
850 Hemorrhage or hematoma complicating a procedure Injuries & Poisonings 1.04 0.992 – 1.09 0.105 2072 20649 all phecode
851
Complications of transplants and reattached
Complications of transplants and reattached limbs
 Injuries & Poisonings 1.05 1.01 – 1.09 0.0241 2982 27545 all phecode
853 Complication of colostomy or enterostomy Injuries & Poisonings 1.18 1.07 – 1.31 0.00139 460 4600 all phecode
854
Complications of cardiac/vascular device
Complications of cardiac/vascular device, implant, and graft
 Injuries & Poisonings 1.14 1.08 – 1.19 1.83e-07 1985 19675 all phecode
855
Complication of nervous system device, implant
Complication of nervous system device, implant, and graft
 Injuries & Poisonings 1.12 0.984 – 1.28 0.0848 264 2640 all phecode
856
Vascular complications of surgery and medical
Vascular complications of surgery and medical procedures
 Injuries & Poisonings 1.15 1.01 – 1.3 0.029 293 2929 all phecode
857
Mechanical complication of unspecified
Mechanical complication of unspecified genitourinary device, implant, and graft
 Injuries & Poisonings 1.05 0.988 – 1.11 0.116 1310 13087 all phecode
858 Complication of internal orthopedic device Injuries & Poisonings 0.998 0.953 – 1.04 0.92 2213 21944 all phecode
859
Complication due to other implant and internal
Complication due to other implant and internal device
 Injuries & Poisonings 1.07 1.02 – 1.12 0.00728 2110 21070 all phecode
860 Bone marrow or stem cell transplant Neoplasms 1.16 0.98 – 1.37 0.0847 166 1660 all phecode
870 Open wounds of head; neck; and trunk Injuries & Poisonings 1.06 1.02 – 1.09 0.00136 4117 36734 all phecode
870.1 Open wound or laceration of eye or eyelid Injuries & Poisonings 1.13 0.976 – 1.32 0.102 204 2026 all phecode
870.2 Open wound of ear Injuries & Poisonings 0.939 0.779 – 1.13 0.509 144 1437 all phecode
870.3 Other open wound of head and face Injuries & Poisonings 0.984 0.927 – 1.04 0.601 1346 13301 all phecode
870.4 Open wound of nose and sinus Injuries & Poisonings 1.01 0.871 – 1.18 0.857 207 2057 all phecode
870.5 Open wound of lip and mouth Injuries & Poisonings 1.1 0.962 – 1.25 0.165 275 2724 all phecode
870.6 Open wound of neck Injuries & Poisonings 1.04 0.9 – 1.21 0.575 214 2128 all phecode
870.8 Open wound of genital organs Injuries & Poisonings 1.1 0.912 – 1.32 0.323 144 1440 all phecode
871 Open wounds of extremities Injuries & Poisonings 1.03 0.996 – 1.07 0.0825 3530 32903 all phecode
871.1 Open wound of hand except finger(s) Injuries & Poisonings 0.982 0.897 – 1.08 0.696 572 5701 all phecode
871.2 Open wound of finger(s) Injuries & Poisonings 1.05 0.977 – 1.12 0.191 984 9772 all phecode
871.3 Open wound of foot except toe(s) alone Injuries & Poisonings 1.08 0.98 – 1.19 0.123 490 4843 all phecode
871.4 Open wound of toe(s) Injuries & Poisonings 1 0.887 – 1.14 0.94 295 2921 all phecode
872 Traumatic amputation Injuries & Poisonings 1.16 1.06 – 1.27 0.0018 551 5477 all phecode
874 Complication of amputation stump Injuries & Poisonings 1.08 0.922 – 1.27 0.331 170 1697 all phecode
875 Non-healing surgical wound Injuries & Poisonings 1.04 0.952 – 1.14 0.373 572 5720 all phecode
876
Posttraumatic wound infection not elsewhere
Posttraumatic wound infection not elsewhere classified
 Injuries & Poisonings 1.18 1.09 – 1.27 2.91e-05 802 8003 all phecode
907 Injuries to the nervous system Injuries & Poisonings 1.05 0.977 – 1.12 0.191 1010 10096 all phecode
910 Superficial injury, infected Injuries & Poisonings 1.02 0.838 – 1.24 0.854 119 1161 all phecode
911 Blister Injuries & Poisonings 0.952 0.842 – 1.08 0.432 302 2996 all phecode
912 Insect bite Injuries & Poisonings 0.951 0.863 – 1.05 0.305 492 4886 all phecode
913 Toxic effect of venom Injuries & Poisonings 0.96 0.853 – 1.08 0.504 337 3326 all phecode
916 Contusion Injuries & Poisonings 1.02 0.989 – 1.06 0.182 4296 38033 all phecode
930 Allergic reaction to food Injuries & Poisonings 0.961 0.888 – 1.04 0.319 763 7596 all phecode
931
Contact dermatitis and other eczema due to
Contact dermatitis and other eczema due to plants [except food]
 Dermatologic 1 0.926 – 1.09 0.919 714 7072 all phecode
938 Dermatitis due to solar radiation Dermatologic 1 0.973 – 1.03 0.843 5567 29098 all phecode
938.1 Acute dermatitis due to solar radiation Dermatologic 0.908 0.783 – 1.05 0.199 217 2164 all phecode
938.2 Chronic dermatitis due to solar radiation Dermatologic 0.999 0.968 – 1.03 0.936 5307 28656 all phecode
939
Atopic/contact dermatitis due to other or
Atopic/contact dermatitis due to other or unspecified
 Dermatologic 1.01 0.985 – 1.04 0.383 6704 32389 all phecode
939.1 Contact and allergic dermatitis of eyelid Dermatologic 0.918 0.731 – 1.15 0.461 91 870 all phecode
941 Adverse reaction to serum or vaccine Injuries & Poisonings 1.23 1.05 – 1.43 0.00867 188 1880 all phecode
942 Infusion and transfusion reaction Injuries & Poisonings 1.11 0.973 – 1.26 0.121 269 2688 all phecode
946 Anaphylactic shock NOS Injuries & Poisonings 0.946 0.859 – 1.04 0.26 500 4940 all phecode
947 Urticaria Dermatologic 1.02 0.958 – 1.09 0.531 1177 11454 all phecode
949 Allergies, other Injuries & Poisonings 1.02 0.993 – 1.05 0.138 7251 32350 all phecode
952
Spinal cord injury without evidence of spinal
Spinal cord injury without evidence of spinal bone injury
 Injuries & Poisonings 1.09 0.992 – 1.2 0.0729 494 4940 all phecode
957 Injury to other and unspecified nerves Injuries & Poisonings 0.996 0.83 – 1.19 0.965 136 1352 all phecode
958
Certain early complications of trauma or
Certain early complications of trauma or procedure
 Injuries & Poisonings 1.05 0.984 – 1.11 0.146 1217 12158 all phecode
958.1 Postoperative shock Injuries & Poisonings 1.04 0.88 – 1.22 0.66 169 1688 all phecode
958.2 Traumatic and surgical subcutaneous emphysema Injuries & Poisonings 1.24 1.02 – 1.51 0.0336 114 1140 all phecode
960 Poisoning by antibiotics Injuries & Poisonings 1.07 1.02 – 1.12 0.00301 2479 22087 all phecode
960.1
Adverse effects of antibacterials (not
Adverse effects of antibacterials (not penicillins)
 Injuries & Poisonings 1.11 0.985 – 1.24 0.0876 342 3403 all phecode
960.2 Allergy/adverse effect of penicillin Injuries & Poisonings 1.06 1 – 1.12 0.0399 1636 16005 all phecode
961 Poisoning by other anti-infectives Injuries & Poisonings 1.1 1.01 – 1.21 0.037 528 5234 all phecode
961.1 Poisoning/allergy of sulfonamides Injuries & Poisonings 1.06 0.992 – 1.13 0.0881 1065 10347 all phecode
962 Poisoning by hormones and synthetic substitutes Injuries & Poisonings 1.01 0.935 – 1.09 0.813 803 7976 all phecode
962.1
Adrenal cortical steroids causing adverse
Adrenal cortical steroids causing adverse effects in therapeutic use
 Injuries & Poisonings 1.05 0.936 – 1.17 0.423 379 3782 all phecode
962.2
Insulins and antidiabetic agents causing
Insulins and antidiabetic agents causing adverse effects in therapeutic use
 Injuries & Poisonings 1.04 0.789 – 1.36 0.793 62 612 all phecode
962.3
Hormones and synthetic substitutes causing
Hormones and synthetic substitutes causing adverse effects in therapeutic use
 Injuries & Poisonings 0.973 0.882 – 1.07 0.593 478 4773 all phecode
963 Poisoning by primarily systemic agents Injuries & Poisonings 1.01 0.966 – 1.05 0.706 2533 24531 all phecode
963.1
Antineoplastic and immunosuppressive drugs
Antineoplastic and immunosuppressive drugs causing adverse effects
 Injuries & Poisonings 1.01 0.967 – 1.06 0.635 2469 24057 all phecode
964
Poisoning by agents primarily affecting blood
Poisoning by agents primarily affecting blood constituents
 Injuries & Poisonings 1.04 0.964 – 1.13 0.287 743 7337 all phecode
964.1 Anticoagulants causing adverse effects Injuries & Poisonings 1.03 0.949 – 1.12 0.473 712 7027 all phecode
965
Poisoning by analgesics, antipyretics, and
Poisoning by analgesics, antipyretics, and antirheumatics
 Injuries & Poisonings 1.04 0.962 – 1.11 0.35 864 8601 all phecode
965.1
Opiates and related narcotics causing adverse
Opiates and related narcotics causing adverse effects in therapeutic use
 Injuries & Poisonings 1.08 1.02 – 1.15 0.00482 1469 14402 all phecode
965.3
Salicylates causing adverse effects in
Salicylates causing adverse effects in therapeutic use
 Injuries & Poisonings 1.03 0.853 – 1.26 0.727 119 1182 all phecode
966
Poisoning by anticonvulsants and
Poisoning by anticonvulsants and anti-Parkinsonism drugs
 Injuries & Poisonings 1.08 0.877 – 1.33 0.471 103 1006 all phecode
967
Adverse effects of sedatives or other central
Adverse effects of sedatives or other central nervous system depressants and anesthetics
 Injuries & Poisonings 1.05 0.987 – 1.11 0.124 1254 12464 all phecode
969 Poisoning by psychotropic agents Injuries & Poisonings 1.14 1 – 1.3 0.05 281 2797 all phecode
971
Poisoning by drugs primarily affecting the
Poisoning by drugs primarily affecting the autonomic nervous system
 Injuries & Poisonings 1.11 0.862 – 1.44 0.412 67 643 all phecode
972
Poisoning by agents primarily affecting the
Poisoning by agents primarily affecting the cardiovascular system
 Injuries & Poisonings 1.17 1.03 – 1.33 0.0151 288 2858 all phecode
972.1
Cardiac rhythm regulators causing adverse
Cardiac rhythm regulators causing adverse effects in therapeutic use
 Injuries & Poisonings 0.972 0.765 – 1.24 0.818 80 776 all phecode
972.6 Antihypertensive agents causing adverse effects Injuries & Poisonings 1.18 0.954 – 1.47 0.125 104 1034 all phecode
974
Poisoning by water, mineral, and uric acid
Poisoning by water, mineral, and uric acid metabolism drugs
 Injuries & Poisonings 1.01 0.83 – 1.23 0.928 113 1130 all phecode
975
Poisoning by agents primarily acting on the
Poisoning by agents primarily acting on the smooth and skeletal muscles and respiratory system
 Injuries & Poisonings 0.911 0.72 – 1.15 0.441 81 810 all phecode
976
Poisoning by agents primarily affecting skin &
Poisoning by agents primarily affecting skin & mucous membrane, ophthalmological, otorhinolaryngological, & dental drugs
 Injuries & Poisonings 1.1 0.85 – 1.42 0.473 71 703 all phecode
977 Personal history of allergy to medicinal agents Injuries & Poisonings 1.08 1.02 – 1.13 0.00412 1763 16599 all phecode
979 Adverse drug events and drug allergies Injuries & Poisonings 1.09 1.05 – 1.13 9.45e-06 3448 30885 all phecode
980
Encounter for long-term (current) use of
Encounter for long-term (current) use of antibiotics
 Infectious Diseases 1 0.946 – 1.06 0.938 1391 13877 all phecode
985 Toxic effect of other metals Injuries & Poisonings 0.962 0.726 – 1.27 0.788 57 564 all phecode
989
Toxic effect of other substances, chiefly
Toxic effect of other substances, chiefly nonmedicinal as to source
 Injuries & Poisonings 1.09 0.9 – 1.32 0.377 129 1275 all phecode
990 Effects radiation NOS Injuries & Poisonings 1 0.969 – 1.04 0.85 3927 31223 all phecode
994 Sepsis and SIRS Injuries & Poisonings 1.09 1.05 – 1.15 0.000126 2192 21710 all phecode
994.1 Systemic inflammatory response syndrome (SIRS) Injuries & Poisonings 1.01 0.891 – 1.14 0.879 291 2910 all phecode
994.2 Sepsis Injuries & Poisonings 1.1 1.05 – 1.15 0.000113 2086 20666 all phecode
994.21 Septic shock Injuries & Poisonings 1.19 1.09 – 1.29 0.000105 627 6260 all phecode
008 Intestinal infection Infectious Diseases 0.985 0.929 – 1.05 0.624 1492 7951 exclusion phecode
008.5 Bacterial enteritis Infectious Diseases 1.03 0.937 – 1.13 0.551 562 3445 exclusion phecode
008.52 Intestinal infection due to C. difficile Infectious Diseases 1.07 0.963 – 1.2 0.198 419 2671 exclusion phecode
008.6 Viral Enteritis Infectious Diseases 0.934 0.835 – 1.04 0.228 419 2167 exclusion phecode
010 Tuberculosis Infectious Diseases 0.915 0.73 – 1.15 0.446 94 621 exclusion phecode
031 Diseases due to other mycobacteria Infectious Diseases 0.88 0.629 – 1.23 0.455 52 238 exclusion phecode
038 Septicemia Infectious Diseases 1.18 1.1 – 1.26 4.18e-06 1029 6197 exclusion phecode
038.1 Gram negative septicemia Infectious Diseases 1.07 0.933 – 1.24 0.32 260 1442 exclusion phecode
038.2 Gram positive septicemia Infectious Diseases 1.08 0.852 – 1.36 0.532 84 604 exclusion phecode
038.3 Bacteremia Infectious Diseases 1.16 1.05 – 1.28 0.00282 523 3000 exclusion phecode
041 Bacterial infection NOS Infectious Diseases 1.07 1.02 – 1.13 0.0051 2242 9823 exclusion phecode
041.1 Staphylococcus infections Infectious Diseases 1.1 1 – 1.21 0.0478 549 4183 exclusion phecode
041.11 Methicillin sensitive Staphylococcus aureus Infectious Diseases 1.1 0.967 – 1.25 0.15 296 2299 exclusion phecode
041.12 Methicillin resistant Staphylococcus aureus Infectious Diseases 1.13 0.976 – 1.3 0.103 238 1939 exclusion phecode
041.2 Streptococcus infection Infectious Diseases 1.12 1.02 – 1.22 0.0153 625 4118 exclusion phecode
041.21 Rheumatic fever / chorea Infectious Diseases 1.12 0.885 – 1.43 0.339 92 652 exclusion phecode
041.4 E. coli Infectious Diseases 1.02 0.921 – 1.13 0.722 490 2997 exclusion phecode
041.8 H. pylori Infectious Diseases 1.01 0.824 – 1.24 0.91 123 728 exclusion phecode
041.9 Infection with drug-resistant microorganisms Infectious Diseases 1.12 0.939 – 1.33 0.212 163 945 exclusion phecode
053 Herpes zoster Infectious Diseases 0.889 0.82 – 0.963 0.00397 826 3468 exclusion phecode
053.1 Herpes zoster with nervous system complications Infectious Diseases 0.881 0.701 – 1.11 0.28 106 481 exclusion phecode
054 Herpes simplex Infectious Diseases 1.02 0.943 – 1.11 0.588 826 3453 exclusion phecode
070 Viral hepatitis Infectious Diseases 1.05 0.929 – 1.19 0.417 325 1713 exclusion phecode
070.1 Viral hepatitis A Infectious Diseases 1.05 0.731 – 1.52 0.784 42 186 exclusion phecode
070.2 Viral hepatitis B Infectious Diseases 1.17 0.909 – 1.5 0.224 88 440 exclusion phecode
070.3 Viral hepatitis C Infectious Diseases 0.985 0.839 – 1.16 0.849 198 1071 exclusion phecode
070.4 Chronic hepatitis Infectious Diseases 1.13 0.896 – 1.42 0.307 93 404 exclusion phecode
070.9 Hepatitis NOS Infectious Diseases 1.07 0.962 – 1.19 0.214 425 2385 exclusion phecode
071 Human immunodeficiency virus [HIV] disease Infectious Diseases 1.43 1.05 – 1.95 0.0225 55 289 exclusion phecode
071.1 HIV infection, symptomatic Infectious Diseases 1.22 0.875 – 1.71 0.237 45 221 exclusion phecode
078 Viral warts & HPV Infectious Diseases 0.961 0.91 – 1.02 0.159 1848 6160 exclusion phecode
079 Viral infection Infectious Diseases 1.02 0.974 – 1.06 0.442 3491 7264 exclusion phecode
079.1 Varicella infection Infectious Diseases 0.995 0.944 – 1.05 0.85 2058 6631 exclusion phecode
079.2 Infectious mononucleosis Infectious Diseases 1.11 0.889 – 1.39 0.357 113 541 exclusion phecode
079.9 Viremia, NOS Infectious Diseases 1.07 0.96 – 1.2 0.212 421 1817 exclusion phecode
080 Postoperative infection Infectious Diseases 0.977 0.906 – 1.05 0.552 831 6878 exclusion phecode
081
Infection/inflammation of internal prosthetic
Infection/inflammation of internal prosthetic device; implant; and graft
 Infectious Diseases 1.13 1.02 – 1.25 0.0151 493 4071 exclusion phecode
090
Sexually transmitted infections (not HIV or
Sexually transmitted infections (not HIV or hepatitis)
 Infectious Diseases 0.934 0.839 – 1.04 0.207 452 2727 exclusion phecode
110 Dermatophytosis / Dermatomycosis Infectious Diseases 0.989 0.938 – 1.04 0.69 1936 7462 exclusion phecode
110.1 Dermatophytosis Infectious Diseases 0.986 0.933 – 1.04 0.613 1791 6843 exclusion phecode
110.11 Dermatophytosis of nail Infectious Diseases 0.996 0.93 – 1.07 0.912 1151 4491 exclusion phecode
110.12 Althete's foot Infectious Diseases 1.02 0.921 – 1.13 0.692 489 2200 exclusion phecode
110.13 Dermatophytosis of the body Infectious Diseases 0.897 0.799 – 1.01 0.0688 408 1997 exclusion phecode
110.2 Dermatomycoses Infectious Diseases 0.986 0.837 – 1.16 0.865 206 1035 exclusion phecode
112 Candidiasis Infectious Diseases 1.05 0.995 – 1.11 0.0754 1630 7500 exclusion phecode
112.3 Candidiasis of skin and nails Infectious Diseases 1.02 0.89 – 1.16 0.819 296 1709 exclusion phecode
117 Mycoses Infectious Diseases 1.02 0.882 – 1.17 0.833 262 1426 exclusion phecode
117.1 Histoplasmosis Infectious Diseases 1.08 0.704 – 1.66 0.718 34 206 exclusion phecode
117.4 Aspergillosis Infectious Diseases 1.25 0.931 – 1.67 0.138 63 335 exclusion phecode
130 Spirochetal infection Infectious Diseases 0.975 0.763 – 1.25 0.838 88 447 exclusion phecode
130.1 Lyme disease Infectious Diseases 0.919 0.688 – 1.23 0.566 64 310 exclusion phecode
131 Protozoan infection Infectious Diseases 0.955 0.632 – 1.44 0.828 30 153 exclusion phecode
132 Infestation (lice, mites) Infectious Diseases 0.901 0.693 – 1.17 0.436 82 516 exclusion phecode
134 Helminthiases Infectious Diseases 1.02 0.694 – 1.5 0.917 36 208 exclusion phecode
134.1 Intestinal helminthiases Infectious Diseases 1.16 0.73 – 1.83 0.536 22 144 exclusion phecode
136 Other infectious and parasitic diseases Infectious Diseases 1.04 0.982 – 1.11 0.169 1320 8682 exclusion phecode
145 Cancer of mouth Neoplasms 0.998 0.87 – 1.15 0.982 240 3814 exclusion phecode
145.1 Cancer of lip Neoplasms 0.699 0.412 – 1.19 0.185 15 184 exclusion phecode
145.2 Cancer of tongue Neoplasms 1.04 0.844 – 1.27 0.739 103 1620 exclusion phecode
145.3 Cancer of major salivary glands Neoplasms 0.969 0.743 – 1.26 0.814 59 952 exclusion phecode
145.4 Cancer of the gums Neoplasms 0.92 0.59 – 1.44 0.715 22 441 exclusion phecode
145.5 Cancer of the mouth floor Neoplasms 0.964 0.665 – 1.4 0.844 30 508 exclusion phecode
149 Cancer of larynx, pharynx, nasal cavities Neoplasms 1 0.873 – 1.15 0.971 232 3374 exclusion phecode
149.1 Cancer of oropharynx Neoplasms 0.788 0.621 – 1 0.0504 73 882 exclusion phecode
149.2 Cancer of nasopharynx Neoplasms 1.38 0.926 – 2.07 0.113 28 284 exclusion phecode
149.3 Cancer of hypopharynx Neoplasms 0.942 0.536 – 1.66 0.836 12 217 exclusion phecode
149.4 Cancer of larynx Neoplasms 1.06 0.812 – 1.39 0.654 59 958 exclusion phecode
149.5
Hx of malignant neoplasm of oral cavity and
Hx of malignant neoplasm of oral cavity and pharynx
 Neoplasms 0.954 0.789 – 1.15 0.628 123 1412 exclusion phecode
149.9 Cancer of of nasal cavities Neoplasms 1.23 0.858 – 1.76 0.261 34 651 exclusion phecode
150 Cancer of esophagus Neoplasms 1.15 0.938 – 1.4 0.182 118 1017 exclusion phecode
151 Cancer of stomach Neoplasms 0.99 0.818 – 1.2 0.914 132 1184 exclusion phecode
153 Colorectal cancer Neoplasms 0.995 0.898 – 1.1 0.93 472 2840 exclusion phecode
153.2 Colon cancer Neoplasms 1.01 0.903 – 1.14 0.833 385 2224 exclusion phecode
153.3
Malignant neoplasm of rectum, rectosigmoid
Malignant neoplasm of rectum, rectosigmoid junction, and anus
 Neoplasms 0.981 0.853 – 1.13 0.79 260 1595 exclusion phecode
155 Cancer of liver and intrahepatic bile duct Neoplasms 1.16 0.974 – 1.39 0.0959 153 1204 exclusion phecode
155.1 Malignant neoplasm of liver, primary Neoplasms 1.05 0.851 – 1.3 0.642 110 821 exclusion phecode
157 Pancreatic cancer Neoplasms 1.21 1.01 – 1.44 0.0372 150 1259 exclusion phecode
158
Neoplasm of unspecified nature of digestive
Neoplasm of unspecified nature of digestive system
 Neoplasms 1.03 0.938 – 1.12 0.579 650 3901 exclusion phecode
159
Malignant neoplasm of other and ill-defined
Malignant neoplasm of other and ill-defined sites within the digestive organs and peritoneum
 Neoplasms 1.05 0.963 – 1.15 0.255 589 4302 exclusion phecode
159.2
Malignant neoplasm of small intestine
Malignant neoplasm of small intestine, including duodenum
 Neoplasms 1.17 0.887 – 1.54 0.267 62 550 exclusion phecode
159.3
Malignant neoplasm of gallbladder and
Malignant neoplasm of gallbladder and extrahepatic bile ducts
 Neoplasms 1.36 0.955 – 1.93 0.0889 36 421 exclusion phecode
159.4
Malignant neoplasm of retroperitoneum and
Malignant neoplasm of retroperitoneum and peritoneum
 Neoplasms 1.18 0.934 – 1.49 0.164 84 713 exclusion phecode
164 Cancer of intrathoracic organs Neoplasms 1.38 1 – 1.91 0.0489 44 373 exclusion phecode
165 Cancer within the respiratory system Neoplasms 1.09 0.967 – 1.23 0.157 314 3557 exclusion phecode
165.1 Cancer of bronchus; lung Neoplasms 1.1 0.962 – 1.25 0.168 273 2815 exclusion phecode
170 Cancer of bone and connective tissue Neoplasms 1.03 0.911 – 1.16 0.671 323 4697 exclusion phecode
170.1 Bone cancer Neoplasms 1.06 0.883 – 1.26 0.55 144 1998 exclusion phecode
170.2 Cancer of connective tissue Neoplasms 1.03 0.89 – 1.19 0.702 219 3267 exclusion phecode
172 Skin cancer Neoplasms 1.04 0.987 – 1.09 0.15 2426 8769 exclusion phecode
172.1 Melanomas of skin, dx or hx Neoplasms 1.04 0.98 – 1.1 0.2 1638 7955 exclusion phecode
172.11 Melanomas of skin Neoplasms 1.1 1.01 – 1.21 0.0321 568 6479 exclusion phecode
172.2 Other non-epithelial cancer of skin Neoplasms 1.02 0.971 – 1.08 0.392 2188 8150 exclusion phecode
172.21 Basal cell carcinoma Neoplasms 1.02 0.959 – 1.09 0.513 1397 6404 exclusion phecode
172.22 Squamous cell carcinoma Neoplasms 1.07 0.988 – 1.16 0.0939 751 4644 exclusion phecode
172.3 Carcinoma in situ of skin Neoplasms 1.1 0.999 – 1.21 0.0513 555 3406 exclusion phecode
173 Neoplasm of uncertain behavior of skin Neoplasms 1.09 1.01 – 1.17 0.0245 956 5266 exclusion phecode
174 Breast cancer Neoplasms 0.954 0.886 – 1.03 0.205 1075 3867 exclusion phecode
174.1 Breast cancer [female] Neoplasms 0.948 0.879 – 1.02 0.167 1022 3660 exclusion phecode
174.11 Malignant neoplasm of female breast Neoplasms 0.948 0.879 – 1.02 0.173 1005 3632 exclusion phecode
174.3 Neoplasm of uncertain behavior of breast Neoplasms 1.01 0.816 – 1.24 0.95 117 548 exclusion phecode
175 Acquired absence of breast Neoplasms 0.883 0.777 – 1 0.0574 314 1695 exclusion phecode
180 Cervical cancer and dysplasia Neoplasms 0.944 0.855 – 1.04 0.256 544 2752 exclusion phecode
180.1 Cervical cancer Neoplasms 0.839 0.682 – 1.03 0.0981 115 1047 exclusion phecode
180.3
Cervical intraepithelial neoplasia [CIN]
Cervical intraepithelial neoplasia [CIN] [Cervical dysplasia]
 Neoplasms 0.927 0.832 – 1.03 0.164 470 2080 exclusion phecode
182 Malignant neoplasm of uterus Neoplasms 0.957 0.812 – 1.13 0.597 168 1782 exclusion phecode
184 Cancer of other female genital organs Neoplasms 0.915 0.815 – 1.03 0.136 358 3085 exclusion phecode
184.1
Malignant neoplasm of ovary and other uterine
Malignant neoplasm of ovary and other uterine adnexa
 Neoplasms 1.02 0.859 – 1.21 0.816 155 1526 exclusion phecode
184.11 Malignant neoplasm of ovary Neoplasms 1.07 0.876 – 1.31 0.506 117 1148 exclusion phecode
184.2
Cancer of other female genital organs
Cancer of other female genital organs (excluding uterus and ovary)
 Neoplasms 0.887 0.765 – 1.03 0.11 216 1624 exclusion phecode
185 Cancer of prostate Neoplasms 0.969 0.877 – 1.07 0.541 662 2333 exclusion phecode
187 Cancer of other male genital organs Neoplasms 1.09 0.871 – 1.35 0.467 93 838 exclusion phecode
187.1
Malignant neoplasm of unspecified male genital
Malignant neoplasm of unspecified male genital organ
 Neoplasms 1.24 0.798 – 1.92 0.342 22 287 exclusion phecode
187.2 Malignant neoplasm of testis Neoplasms 0.959 0.708 – 1.3 0.785 50 435 exclusion phecode
187.8
Neoplasm of uncertain behavior of male genital
Neoplasm of uncertain behavior of male genital organs
 Neoplasms 0.815 0.529 – 1.26 0.356 27 135 exclusion phecode
189
Cancer of urinary organs (incl. kidney and
Cancer of urinary organs (incl. kidney and bladder)
 Neoplasms 1 0.918 – 1.09 0.973 622 6351 exclusion phecode
189.1 Cancer of kidney and renal pelvis Neoplasms 1.03 0.905 – 1.17 0.678 286 3902 exclusion phecode
189.11 Malignant neoplasm of kidney, except pelvis Neoplasms 1.05 0.916 – 1.21 0.465 236 3383 exclusion phecode
189.12 Malignant neoplasm of renal pelvis Neoplasms 0.941 0.703 – 1.26 0.682 50 653 exclusion phecode
189.2 Cancer of bladder Neoplasms 0.984 0.882 – 1.1 0.769 395 4180 exclusion phecode
189.21 Malignant neoplasm of bladder Neoplasms 0.969 0.864 – 1.09 0.587 353 3865 exclusion phecode
189.4 Malignant neoplasm of other urinary organs Neoplasms 0.99 0.824 – 1.19 0.916 139 1786 exclusion phecode
190 Cancer of eye Neoplasms 0.761 0.524 – 1.1 0.151 38 368 exclusion phecode
191
Manlignant and unknown neoplasms of brain and
Manlignant and unknown neoplasms of brain and nervous system
 Neoplasms 1.13 0.979 – 1.31 0.0932 209 2687 exclusion phecode
191.1 Cancer of brain and nervous system Neoplasms 1.24 1.03 – 1.49 0.0215 130 1746 exclusion phecode
191.11 Cancer of brain Neoplasms 1.29 1.05 – 1.58 0.0154 102 1445 exclusion phecode
193 Thyroid cancer Neoplasms 1.03 0.889 – 1.18 0.724 228 2593 exclusion phecode
194 Cancer of other endocrine glands Neoplasms 1.07 0.903 – 1.27 0.432 162 1628 exclusion phecode
195 Cancer, suspected or other Neoplasms 1.03 0.989 – 1.08 0.145 4577 6939 exclusion phecode
195.1 Malignant neoplasm, other Neoplasms 1.03 0.988 – 1.08 0.154 4523 6935 exclusion phecode
195.3 Malignant neoplasm of head, face, and neck Neoplasms 1.02 0.889 – 1.18 0.746 232 2479 exclusion phecode
196 Radiotherapy Neoplasms 0.956 0.884 – 1.03 0.259 852 4536 exclusion phecode
197 Chemotherapy Neoplasms 1.05 0.985 – 1.12 0.134 1385 6192 exclusion phecode
198 Secondary malignant neoplasm Neoplasms 1.07 1 – 1.15 0.0413 1221 6067 exclusion phecode
198.1 Secondary malignancy of lymph nodes Neoplasms 1.05 0.971 – 1.15 0.207 722 5554 exclusion phecode
198.2 Secondary malignancy of respiratory organs Neoplasms 1.09 0.949 – 1.24 0.231 253 2592 exclusion phecode
198.3
Secondary malignant neoplasm of digestive
Secondary malignant neoplasm of digestive systems
 Neoplasms 1.27 1.1 – 1.47 0.00091 229 2134 exclusion phecode
198.4 Secondary malignant neoplasm of liver Neoplasms 1.18 1.01 – 1.37 0.0376 197 1925 exclusion phecode
198.5 Secondary malignancy of brain/spine Neoplasms 1.23 1.01 – 1.5 0.0389 118 1569 exclusion phecode
198.6 Secondary malignancy of bone Neoplasms 1.04 0.893 – 1.2 0.631 213 2103 exclusion phecode
198.7 Secondary malignant neoplasm of skin Neoplasms 1.07 0.829 – 1.39 0.591 70 870 exclusion phecode
199 Neoplasm of uncertain behavior Neoplasms 1.01 0.952 – 1.07 0.8 1851 6816 exclusion phecode
199.4 Neurofibromatosis Neoplasms 1.04 0.64 – 1.68 0.881 19 219 exclusion phecode
200 Myeloproliferative disease Neoplasms 1.09 0.986 – 1.22 0.0898 431 3011 exclusion phecode
200.1 Polycythemia vera Neoplasms 1.33 1.04 – 1.7 0.021 84 623 exclusion phecode
201 Hodgkin's disease Neoplasms 0.892 0.673 – 1.18 0.426 63 454 exclusion phecode
202 Cancer of other lymphoid, histiocytic tissue Neoplasms 0.997 0.904 – 1.1 0.96 498 4266 exclusion phecode
202.2 Non-Hodgkins lymphoma Neoplasms 0.985 0.886 – 1.1 0.786 425 3650 exclusion phecode
202.21 Nodular lymphoma Neoplasms 1.03 0.899 – 1.19 0.646 248 1933 exclusion phecode
202.22 Reticulosarcoma Neoplasms 1.14 0.862 – 1.5 0.361 57 459 exclusion phecode
202.24 Large cell lymphoma Neoplasms 1.03 0.769 – 1.37 0.865 52 411 exclusion phecode
204 Leukemia Neoplasms 1.19 1.04 – 1.37 0.0144 257 1867 exclusion phecode
204.1 Lymphoid leukemia Neoplasms 0.799 0.619 – 1.03 0.0844 75 622 exclusion phecode
204.11 Lymphoid leukemia, acute Neoplasms 0.748 0.5 – 1.12 0.159 32 173 exclusion phecode
204.12 Lymphoid leukemia, chronic Neoplasms 0.864 0.643 – 1.16 0.33 54 471 exclusion phecode
204.2 Myeloid leukemia Neoplasms 1.33 1.08 – 1.63 0.0076 114 763 exclusion phecode
204.21 Myeloid leukemia, acute Neoplasms 1.21 0.922 – 1.58 0.171 63 437 exclusion phecode
204.22 Myeloid leukemia, chronic Neoplasms 1.1 0.705 – 1.73 0.664 23 164 exclusion phecode
204.4 Multiple myeloma Neoplasms 1.36 1.07 – 1.74 0.0136 84 589 exclusion phecode
208 Benign neoplasm of colon Neoplasms 0.985 0.947 – 1.02 0.454 4947 7452 exclusion phecode
209 Neuroendocrine tumors Neoplasms 0.94 0.726 – 1.22 0.638 78 717 exclusion phecode
210 Benign neoplasm of lip, oral cavity, and pharynx Neoplasms 0.932 0.84 – 1.03 0.185 431 4824 exclusion phecode
211
Benign neoplasm of other parts of digestive
Benign neoplasm of other parts of digestive system
 Neoplasms 1.03 0.991 – 1.08 0.124 3160 8867 exclusion phecode
212
Benign neoplasm of respiratory and
Benign neoplasm of respiratory and intrathoracic organs
 Neoplasms 1.1 0.994 – 1.21 0.0668 488 4646 exclusion phecode
213 Benign neoplasm of bone and articular cartilage Neoplasms 0.988 0.886 – 1.1 0.826 417 2726 exclusion phecode
214 Lipoma Neoplasms 1.01 0.919 – 1.1 0.906 628 3935 exclusion phecode
214.1 Lipoma of skin and subcutaneous tissue Neoplasms 1.05 0.939 – 1.18 0.388 397 2464 exclusion phecode
215
Other benign neoplasm of connective and other
Other benign neoplasm of connective and other soft tissue
 Neoplasms 0.95 0.897 – 1.01 0.0838 1501 10164 exclusion phecode
216 Benign neoplasm of skin Neoplasms 1.01 0.971 – 1.05 0.661 5145 7545 exclusion phecode
216.1 Screening for malignant neoplasms of the skin Neoplasms 0.948 0.752 – 1.19 0.649 106 401 exclusion phecode
217 Vascular hamartomas and non-neoplastic nevi Neoplasms 0.942 0.877 – 1.01 0.0988 1043 3992 exclusion phecode
217.1 Nevus, non-neoplastic Neoplasms 0.943 0.877 – 1.01 0.113 1006 3794 exclusion phecode
218 Benign neoplasm of uterus Neoplasms 0.991 0.936 – 1.05 0.758 2036 3991 exclusion phecode
218.1 Uterine leiomyoma Neoplasms 0.961 0.888 – 1.04 0.317 877 3740 exclusion phecode
218.2 Other benign neoplasm of uterus Neoplasms 1.01 0.948 – 1.07 0.783 1639 3889 exclusion phecode
220 Benign neoplasm of ovary Neoplasms 0.976 0.86 – 1.11 0.712 313 1834 exclusion phecode
221 Benign neoplasm of other female genital organs Neoplasms 0.984 0.901 – 1.07 0.724 681 3209 exclusion phecode
222 Benign neoplasm of male genital organs Neoplasms 0.968 0.865 – 1.08 0.565 387 2784 exclusion phecode
223
Benign neoplasm of kidney and other urinary
Benign neoplasm of kidney and other urinary organs
 Neoplasms 0.957 0.856 – 1.07 0.436 421 2243 exclusion phecode
224 Benign neoplasm of eye Neoplasms 0.913 0.809 – 1.03 0.143 341 1995 exclusion phecode
224.1 Benign neoplasm of eye, uveal Neoplasms 0.916 0.805 – 1.04 0.18 310 1727 exclusion phecode
225
Benign neoplasm of brain and other parts of
Benign neoplasm of brain and other parts of nervous system
 Neoplasms 1.09 0.963 – 1.24 0.173 292 3163 exclusion phecode
225.1
Benign neoplasm of brain, cranial nerves
Benign neoplasm of brain, cranial nerves, meninges
 Neoplasms 1.16 1.01 – 1.34 0.0425 217 2457 exclusion phecode
225.2 Benign neoplasm of spinal cord, meninges Neoplasms 0.984 0.785 – 1.23 0.888 84 755 exclusion phecode
226 Benign neoplasm of thyroid glands Neoplasms 0.935 0.839 – 1.04 0.223 414 3786 exclusion phecode
227
Benign neoplasm of other endocrine glands and
Benign neoplasm of other endocrine glands and related structures
 Neoplasms 0.975 0.871 – 1.09 0.661 362 4595 exclusion phecode
227.1 Benign neoplasm of adrenal gland Neoplasms 1.07 0.876 – 1.31 0.495 111 1339 exclusion phecode
227.2 Benign neoplasm of parathyroid gland Neoplasms 1.01 0.86 – 1.19 0.904 173 2107 exclusion phecode
227.3
Benign neoplasm of pituitary gland and
Benign neoplasm of pituitary gland and craniopharyngeal duct (pouch)
 Neoplasms 0.854 0.671 – 1.09 0.2 77 1180 exclusion phecode
228 Hemangioma and lymphangioma, any site Neoplasms 0.993 0.929 – 1.06 0.845 1147 5861 exclusion phecode
228.1 Hemangioma of skin and subcutaneous tissue Neoplasms 0.979 0.903 – 1.06 0.602 803 3820 exclusion phecode
229 Benign neoplasm of unspecified sites Neoplasms 1.02 0.964 – 1.07 0.526 1777 9952 exclusion phecode
229.1 Benign neoplasm of lymph nodes Neoplasms 1.05 0.98 – 1.12 0.172 1082 9218 exclusion phecode
240 Simple and unspecified goiter Endocrine/metabolic 0.959 0.864 – 1.07 0.437 464 2862 exclusion phecode
241 Nontoxic nodular goiter Endocrine/metabolic 0.994 0.928 – 1.07 0.876 1078 6107 exclusion phecode
241.1 Nontoxic uninodular goiter Endocrine/metabolic 1.01 0.935 – 1.09 0.827 876 5483 exclusion phecode
241.2 Nontoxic multinodular goiter Endocrine/metabolic 0.992 0.896 – 1.1 0.878 472 3496 exclusion phecode
242 Thyrotoxicosis with or without goiter Endocrine/metabolic 1.02 0.928 – 1.11 0.729 606 3837 exclusion phecode
242.1 Graves' disease Endocrine/metabolic 0.958 0.82 – 1.12 0.591 208 1420 exclusion phecode
242.2 Toxic multinodular goiter Endocrine/metabolic 1.05 0.742 – 1.5 0.766 38 363 exclusion phecode
242.3 Exophthalmos Endocrine/metabolic 1.2 0.973 – 1.48 0.0888 97 779 exclusion phecode
242.31 Thyrotoxic exophthalmos Endocrine/metabolic 1.13 0.827 – 1.56 0.435 46 372 exclusion phecode
244 Hypothyroidism Endocrine/metabolic 0.989 0.943 – 1.04 0.654 2648 8643 exclusion phecode
244.1 Secondary hypothyroidism Endocrine/metabolic 1.03 0.939 – 1.13 0.524 561 4636 exclusion phecode
244.2 Acquired hypothyroidism Endocrine/metabolic 0.939 0.853 – 1.03 0.197 549 3419 exclusion phecode
244.4 Hypothyroidism NOS Endocrine/metabolic 0.986 0.939 – 1.03 0.559 2543 8526 exclusion phecode
245 Thyroiditis Endocrine/metabolic 0.956 0.848 – 1.08 0.465 363 2382 exclusion phecode
245.2 Chronic thyroiditis Endocrine/metabolic 0.935 0.816 – 1.07 0.329 289 2004 exclusion phecode
245.21 Chronic lymphocytic thyroiditis Endocrine/metabolic 0.923 0.806 – 1.06 0.242 287 1988 exclusion phecode
246 Other disorders of thyroid Endocrine/metabolic 0.982 0.93 – 1.04 0.509 1948 8000 exclusion phecode
246.2 Thyroid cyst Endocrine/metabolic 1.5 1.07 – 2.1 0.0172 49 253 exclusion phecode
246.7 Abnormal results of function study of thyroid Endocrine/metabolic 1.03 0.926 – 1.14 0.602 465 2625 exclusion phecode
249 Secondary diabetes mellitus Endocrine/metabolic 1.09 0.968 – 1.23 0.153 451 1862 exclusion phecode
250 Diabetes mellitus Endocrine/metabolic 1.02 0.981 – 1.07 0.288 5284 7370 exclusion phecode
250.1 Type 1 diabetes Endocrine/metabolic 1.05 0.951 – 1.15 0.352 1276 2670 exclusion phecode
250.11 Type 1 diabetes with ketoacidosis Endocrine/metabolic 1.17 0.928 – 1.48 0.184 188 245 exclusion phecode
250.12 Type 1 diabetes with renal manifestations Endocrine/metabolic 0.998 0.845 – 1.18 0.982 352 655 exclusion phecode
250.13 Type 1 diabetes with ophthalmic manifestations Endocrine/metabolic 1.12 0.957 – 1.3 0.162 528 708 exclusion phecode
250.14 Type 1 diabetes with neurological manifestations Endocrine/metabolic 1.07 0.911 – 1.26 0.406 422 629 exclusion phecode
250.15
Diabetes type 1 with peripheral circulatory
Diabetes type 1 with peripheral circulatory disorders
 Endocrine/metabolic 1.02 0.792 – 1.31 0.883 115 219 exclusion phecode
250.2 Type 2 diabetes Endocrine/metabolic 1.04 0.99 – 1.1 0.111 3099 6949 exclusion phecode
250.21 Type 2 diabetes with ketoacidosis Endocrine/metabolic 1.38 1.1 – 1.73 0.00608 174 321 exclusion phecode
250.22 Type 2 diabetes with renal manifestations Endocrine/metabolic 1.08 0.978 – 1.19 0.13 685 3064 exclusion phecode
250.23 Type 2 diabetes with ophthalmic manifestations Endocrine/metabolic 0.992 0.891 – 1.1 0.882 776 2274 exclusion phecode
250.24 Type 2 diabetes with neurological manifestations Endocrine/metabolic 1.03 0.945 – 1.13 0.465 952 3788 exclusion phecode
250.25
Diabetes type 2 with peripheral circulatory
Diabetes type 2 with peripheral circulatory disorders
 Endocrine/metabolic 1.04 0.899 – 1.19 0.631 339 1427 exclusion phecode
250.3 Insulin pump user Endocrine/metabolic 1.13 1.04 – 1.23 0.00278 1378 4708 exclusion phecode
250.4 Abnormal glucose Endocrine/metabolic 1.02 0.977 – 1.07 0.342 4169 7197 exclusion phecode
250.41 Impaired fasting glucose Endocrine/metabolic 0.977 0.905 – 1.06 0.562 998 3925 exclusion phecode
250.42 Other abnormal glucose Endocrine/metabolic 1.02 0.975 – 1.07 0.366 3750 7074 exclusion phecode
250.5 Glycosuria or Acetonuria Endocrine/metabolic 0.964 0.707 – 1.32 0.819 57 279 exclusion phecode
250.6 Polyneuropathy in diabetes Endocrine/metabolic 1.04 0.946 – 1.15 0.398 838 3069 exclusion phecode
250.7 Diabetic retinopathy Endocrine/metabolic 0.985 0.902 – 1.08 0.742 848 2694 exclusion phecode
251 Other disorders of pancreatic internal secretion Endocrine/metabolic 1.06 0.954 – 1.17 0.297 502 2430 exclusion phecode
251.1 Hypoglycemia Endocrine/metabolic 1.11 0.994 – 1.24 0.0643 639 1868 exclusion phecode
252 Disorders of parathyroid gland Endocrine/metabolic 0.942 0.869 – 1.02 0.149 734 5847 exclusion phecode
252.1 Hyperparathyroidism Endocrine/metabolic 0.942 0.866 – 1.03 0.168 684 5395 exclusion phecode
252.2 Hypoparathyroidism Endocrine/metabolic 1.04 0.859 – 1.25 0.716 136 1276 exclusion phecode
253
Disorders of the pituitary gland and its
Disorders of the pituitary gland and its hypothalamic control
 Endocrine/metabolic 0.969 0.85 – 1.11 0.639 272 2305 exclusion phecode
253.1 Pituitary hyperfunction Endocrine/metabolic 1.04 0.82 – 1.32 0.752 89 708 exclusion phecode
253.11 Acromegaly and gigantism Endocrine/metabolic 0.944 0.512 – 1.74 0.855 11 186 exclusion phecode
253.2 Pituitary hypofunction Endocrine/metabolic 1.11 0.813 – 1.51 0.515 46 587 exclusion phecode
253.3 Diabetes insipidus Endocrine/metabolic 1.19 0.799 – 1.77 0.392 25 258 exclusion phecode
253.4 Anterior pituitary disorders Endocrine/metabolic 1.14 0.833 – 1.57 0.407 48 348 exclusion phecode
253.7 Other disorders of neurohypophysis Endocrine/metabolic 1.09 0.788 – 1.51 0.596 50 269 exclusion phecode
255 Disorders of adrenal glands Endocrine/metabolic 0.994 0.901 – 1.1 0.908 494 4003 exclusion phecode
255.1 Adrenal hyperfunction Endocrine/metabolic 1.03 0.826 – 1.27 0.82 103 1042 exclusion phecode
255.11 Cushing's syndrome Endocrine/metabolic 1.01 0.739 – 1.39 0.932 45 514 exclusion phecode
255.12 Hyperaldosteronism Endocrine/metabolic 1.25 0.871 – 1.79 0.226 35 382 exclusion phecode
255.2 Adrenal hypofunction Endocrine/metabolic 0.959 0.825 – 1.11 0.585 223 1700 exclusion phecode
255.21 Glucocorticoid deficiency Endocrine/metabolic 0.943 0.809 – 1.1 0.455 209 1594 exclusion phecode
256 Ovarian dysfunction Endocrine/metabolic 0.987 0.893 – 1.09 0.799 520 2862 exclusion phecode
256.4 Polycystic ovaries Endocrine/metabolic 0.973 0.857 – 1.11 0.677 322 1903 exclusion phecode
257 Testicular dysfunction Endocrine/metabolic 1.01 0.909 – 1.13 0.812 423 2351 exclusion phecode
257.1 Testicular hypofunction Endocrine/metabolic 1.04 0.929 – 1.16 0.514 411 2252 exclusion phecode
258 Iatrogenic endocrine disorders Endocrine/metabolic 1.41 0.951 – 2.08 0.0879 31 248 exclusion phecode
258.1 Postablative ovarian failure Endocrine/metabolic 0.947 0.68 – 1.32 0.749 52 295 exclusion phecode
259 Other endocrine disorders Endocrine/metabolic 0.965 0.868 – 1.07 0.508 442 2814 exclusion phecode
260 Protein-calorie malnutrition Endocrine/metabolic 1.18 1.1 – 1.26 2.99e-06 1103 5707 exclusion phecode
260.1 Cachexia Endocrine/metabolic 1.17 0.947 – 1.44 0.148 127 585 exclusion phecode
260.2 severe protein-calorie malnutrition Endocrine/metabolic 1.2 1.1 – 1.31 3.69e-05 651 3549 exclusion phecode
260.22 Nutritional marasmus Endocrine/metabolic 1.2 1.04 – 1.38 0.0108 254 1327 exclusion phecode
260.3 Adult failure to thrive Endocrine/metabolic 1.14 0.986 – 1.31 0.0767 259 1307 exclusion phecode
260.6 Anorexia Endocrine/metabolic 1.03 0.913 – 1.17 0.6 344 1906 exclusion phecode
260.7 Polyphagia Endocrine/metabolic 0.826 0.529 – 1.29 0.4 28 219 exclusion phecode
261 Vitamin deficiency Endocrine/metabolic 1.03 0.987 – 1.08 0.172 3713 7777 exclusion phecode
261.1 Vitamin A deficiency Endocrine/metabolic 1.39 0.957 – 2.02 0.0836 38 174 exclusion phecode
261.2 Vitamin B-complex deficiencies Endocrine/metabolic 1.08 0.96 – 1.21 0.206 393 1967 exclusion phecode
261.4 Vitamin D deficiency Endocrine/metabolic 1.02 0.976 – 1.06 0.392 3513 7780 exclusion phecode
261.41 Rickets or osteomalacia Endocrine/metabolic 1.08 0.67 – 1.73 0.759 25 118 exclusion phecode
262 Mineral deficiency NEC Endocrine/metabolic 1.09 0.99 – 1.19 0.0793 634 2775 exclusion phecode
263 Other nutritional deficiency Endocrine/metabolic 1.07 0.98 – 1.16 0.135 730 3710 exclusion phecode
264 Lack of normal physiological development Endocrine/metabolic 1.05 0.826 – 1.34 0.674 97 474 exclusion phecode
264.2 Failure to thrive (childhood) Endocrine/metabolic 1.13 0.799 – 1.6 0.49 45 243 exclusion phecode
264.9
Lack of normal physiological development
Lack of normal physiological development, unspecified
 Endocrine/metabolic 1.04 0.724 – 1.49 0.841 39 155 exclusion phecode
269 Proteinuria Endocrine/metabolic 1.03 0.949 – 1.12 0.47 745 3968 exclusion phecode
270
Disorders of protein plasma/amino-acid
Disorders of protein plasma/amino-acid transport and metabolism
 Endocrine/metabolic 1.03 0.926 – 1.15 0.568 426 2616 exclusion phecode
270.1 Disturbances of amino-acid transport Endocrine/metabolic 1.02 0.765 – 1.35 0.912 57 435 exclusion phecode
270.11
Disturbances of sulphur-bearing amino-acid
Disturbances of sulphur-bearing amino-acid metabolism
 Endocrine/metabolic 0.849 0.621 – 1.16 0.302 48 359 exclusion phecode
270.2 Disorders of amino-acid metabolism Endocrine/metabolic 0.914 0.648 – 1.29 0.607 41 262 exclusion phecode
270.3 Disorders of plasma protein metabolism Endocrine/metabolic 1.04 0.926 – 1.18 0.481 351 2013 exclusion phecode
270.32 Paraproteinemia Endocrine/metabolic 0.991 0.835 – 1.17 0.913 177 1093 exclusion phecode
270.33 Amyloidosis Endocrine/metabolic 0.987 0.656 – 1.48 0.949 23 204 exclusion phecode
270.34 Alpha-1-antitrypsin deficiency Endocrine/metabolic 1.03 0.675 – 1.58 0.884 32 193 exclusion phecode
270.38
Other specified disorders of plasma protein
Other specified disorders of plasma protein metabolism
 Endocrine/metabolic 1.12 0.937 – 1.35 0.207 148 783 exclusion phecode
271
Disorders of carbohydrate transport and
Disorders of carbohydrate transport and metabolism
 Endocrine/metabolic 0.934 0.881 – 0.99 0.0219 1543 7632 exclusion phecode
271.3
Intestinal disaccharidase deficiencies and
Intestinal disaccharidase deficiencies and disaccharide malabsorption
 Endocrine/metabolic 0.934 0.88 – 0.991 0.0234 1512 7443 exclusion phecode
271.9
Other disorders of carbohydrate transport and
Other disorders of carbohydrate transport and metabolism
 Endocrine/metabolic 0.742 0.513 – 1.07 0.112 41 287 exclusion phecode
272 Disorders of lipoid metabolism Endocrine/metabolic 1.16 1.11 – 1.21 6.53e-12 6742 5943 exclusion phecode
272.1 Hyperlipidemia Endocrine/metabolic 1.16 1.11 – 1.21 4.62e-12 6717 5939 exclusion phecode
272.11 Hypercholesterolemia Endocrine/metabolic 1.17 1.1 – 1.24 1.22e-07 2414 4912 exclusion phecode
272.12 Hyperglyceridemia Endocrine/metabolic 1.56 1.36 – 1.78 1.11e-10 273 2564 exclusion phecode
272.13 Mixed hyperlipidemia Endocrine/metabolic 1.23 1.14 – 1.31 8.69e-09 1621 4093 exclusion phecode
272.9 Unspecified disorder of lipoid metabolism Endocrine/metabolic 1.17 0.966 – 1.41 0.109 165 672 exclusion phecode
274 Gout and other crystal arthropathies Endocrine/metabolic 1.01 0.931 – 1.09 0.886 804 6125 exclusion phecode
274.1 Gout Endocrine/metabolic 1.02 0.942 – 1.11 0.612 746 5905 exclusion phecode
274.11 Gouty arthropathy Endocrine/metabolic 1.04 0.928 – 1.16 0.517 399 2932 exclusion phecode
274.2 Crystal arthropathies Endocrine/metabolic 0.964 0.77 – 1.21 0.752 96 549 exclusion phecode
274.21 Chondrocalcinosis Endocrine/metabolic 1.01 0.799 – 1.27 0.942 89 509 exclusion phecode
275 Disorders of mineral metabolism Endocrine/metabolic 1.02 0.967 – 1.08 0.432 1604 9816 exclusion phecode
275.1 Disorders of iron metabolism Hematopoietic 1.23 0.984 – 1.53 0.0696 98 587 exclusion phecode
275.11 Hereditary hemochromatosis Hematopoietic 1.07 0.724 – 1.58 0.734 33 274 exclusion phecode
275.2 Disorders of copper metabolism Endocrine/metabolic 1.21 0.835 – 1.76 0.31 34 189 exclusion phecode
275.3 Disorders of magnesium metabolism Endocrine/metabolic 1.06 0.951 – 1.18 0.29 411 3062 exclusion phecode
275.5 Disorders of calcium/phosphorus metabolism Endocrine/metabolic 0.995 0.934 – 1.06 0.867 1244 8398 exclusion phecode
275.51 Hypocalcemia Endocrine/metabolic 1.06 0.926 – 1.21 0.408 280 2302 exclusion phecode
275.53 Disorders of phosphorus metabolism Endocrine/metabolic 1.04 0.941 – 1.14 0.455 531 3511 exclusion phecode
275.6 Hypercalcemia Endocrine/metabolic 1.02 0.932 – 1.12 0.623 576 4008 exclusion phecode
276
Disorders of fluid, electrolyte, and acid-base
Disorders of fluid, electrolyte, and acid-base balance
 Endocrine/metabolic 1.06 1.02 – 1.11 0.0052 3759 8867 exclusion phecode
276.1 Electrolyte imbalance Endocrine/metabolic 1.09 1.04 – 1.14 0.000697 2616 8300 exclusion phecode
276.11 Hyperosmolality and/or hypernatremia Endocrine/metabolic 1.07 0.932 – 1.24 0.325 257 1305 exclusion phecode
276.12 Hyposmolality and/or hyponatremia Endocrine/metabolic 1.11 1.04 – 1.19 0.0028 1054 5443 exclusion phecode
276.13 Hyperpotassemia Endocrine/metabolic 1.07 1 – 1.14 0.0451 1296 6115 exclusion phecode
276.14 Hypopotassemia Endocrine/metabolic 1.07 0.993 – 1.15 0.077 924 5056 exclusion phecode
276.4 Acid-base balance disorder Endocrine/metabolic 1.1 1.02 – 1.19 0.01 900 4796 exclusion phecode
276.41 Acidosis Endocrine/metabolic 1.1 1.01 – 1.19 0.0287 752 4165 exclusion phecode
276.42 Alkalosis Endocrine/metabolic 1.08 0.924 – 1.25 0.347 231 1129 exclusion phecode
276.5 Hypovolemia Endocrine/metabolic 1.06 1 – 1.12 0.0377 1909 8172 exclusion phecode
276.6 Fluid overload Endocrine/metabolic 1.11 1.02 – 1.21 0.0217 644 3126 exclusion phecode
276.8 Polydipsia Endocrine/metabolic 1.1 0.822 – 1.47 0.518 66 340 exclusion phecode
277 Other disorders of metabolism Endocrine/metabolic 1.02 0.971 – 1.08 0.367 1803 9234 exclusion phecode
277.2
Other disorders of purine and pyrimidine
Other disorders of purine and pyrimidine metabolism
 Endocrine/metabolic 0.973 0.817 – 1.16 0.756 162 1227 exclusion phecode
277.4 Disorders of bilirubin excretion Endocrine/metabolic 1.06 0.944 – 1.2 0.314 346 1886 exclusion phecode
277.5 Other disorders of lipoid metabolism Endocrine/metabolic 1.04 0.93 – 1.16 0.499 420 2663 exclusion phecode
277.51 Lipoprotein disorders Endocrine/metabolic 1.06 0.94 – 1.2 0.328 336 2199 exclusion phecode
277.7 Dysmetabolic syndrome X Endocrine/metabolic 1.17 1.04 – 1.31 0.0073 382 2590 exclusion phecode
278 Overweight, obesity and other hyperalimentation Endocrine/metabolic 0.961 0.926 – 0.998 0.0373 5991 6842 exclusion phecode
278.1 Obesity Endocrine/metabolic 0.957 0.92 – 0.995 0.0265 4904 6838 exclusion phecode
278.11 Morbid obesity Endocrine/metabolic 0.934 0.889 – 0.981 0.00681 2504 6768 exclusion phecode
278.3 Localized adiposity Endocrine/metabolic 1.05 0.873 – 1.25 0.627 149 860 exclusion phecode
278.4 Abnormal weight gain Endocrine/metabolic 0.944 0.881 – 1.01 0.109 1148 4550 exclusion phecode
279 Disorders involving the immune mechanism Endocrine/metabolic 0.992 0.932 – 1.06 0.811 1276 7115 exclusion phecode
279.1 Immunity deficiency Endocrine/metabolic 0.989 0.893 – 1.09 0.826 506 2855 exclusion phecode
279.11 Deficiency of humoral immunity Endocrine/metabolic 1.03 0.851 – 1.25 0.763 146 819 exclusion phecode
279.2 Autoimmune disease NEC Endocrine/metabolic 0.994 0.883 – 1.12 0.927 360 2057 exclusion phecode
279.7 Other immunological findings Endocrine/metabolic 0.992 0.946 – 1.04 0.756 2368 9031 exclusion phecode
279.8
Other specified disorders involving the immune
Other specified disorders involving the immune mechanism
 Endocrine/metabolic 0.999 0.878 – 1.14 0.986 294 1615 exclusion phecode
280 Iron deficiency anemias Hematopoietic 1.02 0.965 – 1.07 0.546 2160 7115 exclusion phecode
280.1
Iron deficiency anemias, unspecified or not due
Iron deficiency anemias, unspecified or not due to blood loss
 Hematopoietic 1.02 0.97 – 1.08 0.421 2093 7064 exclusion phecode
280.2
Iron deficiency anemia secondary to blood loss
Iron deficiency anemia secondary to blood loss (chronic)
 Hematopoietic 1.01 0.933 – 1.1 0.77 818 3936 exclusion phecode
281 Other deficiency anemia Hematopoietic 1.03 0.897 – 1.19 0.651 264 1166 exclusion phecode
281.1 Megaloblastic anemia Hematopoietic 1.19 0.974 – 1.45 0.0886 137 590 exclusion phecode
281.11 Pernicious anemia Hematopoietic 1.2 0.874 – 1.64 0.264 60 268 exclusion phecode
281.12 Other vitamin B12 deficiency anemia Hematopoietic 1.09 0.863 – 1.38 0.468 94 431 exclusion phecode
281.9 Deficiency anemias Hematopoietic 1.04 0.852 – 1.26 0.714 145 652 exclusion phecode
282 Hereditary hemolytic anemias Hematopoietic 1.01 0.843 – 1.21 0.908 141 781 exclusion phecode
282.8 Other hemoglobinopathies Hematopoietic 0.99 0.792 – 1.24 0.93 96 540 exclusion phecode
282.9 Other hereditary hemolytic anemias Hematopoietic 1.11 0.868 – 1.42 0.407 84 457 exclusion phecode
283 Acquired hemolytic anemias Hematopoietic 1.18 0.901 – 1.54 0.229 66 348 exclusion phecode
283.1 Autoimmune hemolytic anemias Hematopoietic 0.978 0.664 – 1.44 0.912 29 149 exclusion phecode
284 Aplastic anemia Hematopoietic 1.31 1.15 – 1.5 4.44e-05 299 1565 exclusion phecode
284.1 Pancytopenia Hematopoietic 1.31 1.13 – 1.51 0.000242 260 1368 exclusion phecode
285 Other anemias Hematopoietic 1.03 0.989 – 1.07 0.158 4587 7711 exclusion phecode
285.1 Acute posthemorrhagic anemia Hematopoietic 1.09 1.02 – 1.17 0.00779 1275 6062 exclusion phecode
285.2 Anemia of chronic disease Hematopoietic 1.1 1.02 – 1.19 0.0195 834 4467 exclusion phecode
285.21 Anemia in chronic kidney disease Hematopoietic 1.11 0.986 – 1.24 0.085 406 2179 exclusion phecode
285.22 Anemia in neoplastic disease Hematopoietic 1.02 0.883 – 1.19 0.746 230 1478 exclusion phecode
286 Coagulation defects Hematopoietic 1.01 0.957 – 1.07 0.646 1531 8279 exclusion phecode
286.1 Congenital coagulation defects Hematopoietic 1 0.796 – 1.27 0.972 89 644 exclusion phecode
286.11 Von willebrand's disease Hematopoietic 1.06 0.698 – 1.62 0.778 31 214 exclusion phecode
286.12
Congenital deficiency of other clotting factors
Congenital deficiency of other clotting factors (including factor VII)
 Hematopoietic 0.952 0.68 – 1.33 0.774 43 330 exclusion phecode
286.2
Encounter for long-term (current) use of
Encounter for long-term (current) use of anticoagulants
 Hematopoietic 0.988 0.929 – 1.05 0.714 1416 6258 exclusion phecode
286.3
Coagulation defects complicating pregnancy or
Coagulation defects complicating pregnancy or postpartum
 Hematopoietic 0.753 0.533 – 1.06 0.108 46 269 exclusion phecode
286.4 Acquired coagulation factor deficiency Hematopoietic 1.24 1.01 – 1.51 0.0388 121 637 exclusion phecode
286.5
Hemorrhagic disorder due to intrinsic
Hemorrhagic disorder due to intrinsic circulating anticoagulants
 Hematopoietic 0.801 0.588 – 1.09 0.159 58 314 exclusion phecode
286.6 Defibrination syndrome Hematopoietic 0.974 0.907 – 1.05 0.469 972 6303 exclusion phecode
286.7 Other and unspecified coagulation defects Hematopoietic 1 0.937 – 1.07 0.996 1182 7257 exclusion phecode
286.8 Hypercoagulable state Hematopoietic 1.04 0.915 – 1.18 0.557 301 2144 exclusion phecode
286.81 Primary hypercoagulable state Hematopoietic 1.02 0.898 – 1.16 0.734 289 2098 exclusion phecode
286.9 Abnormal coagulation profile Hematopoietic 1.03 0.932 – 1.13 0.593 541 2777 exclusion phecode
287 Purpura and other hemorrhagic conditions Hematopoietic 1.09 1.02 – 1.16 0.00689 1404 6947 exclusion phecode
287.1 Spontaneous ecchymoses Hematopoietic 1.07 0.854 – 1.33 0.572 106 523 exclusion phecode
287.3 Thrombocytopenia Hematopoietic 1.09 1.02 – 1.16 0.0107 1255 6393 exclusion phecode
287.31 Primary thrombocytopenia Hematopoietic 1.05 0.902 – 1.23 0.515 208 1392 exclusion phecode
287.32 Secondary thrombocytopenia Hematopoietic 1.05 0.906 – 1.23 0.493 222 1390 exclusion phecode
287.4 Qualitative platelet defects Hematopoietic 1.53 1.08 – 2.16 0.0162 48 281 exclusion phecode
288 Diseases of white blood cells Hematopoietic 1.03 0.975 – 1.08 0.311 1995 8845 exclusion phecode
288.1 Decreased white blood cell count Hematopoietic 1.04 0.95 – 1.13 0.431 687 3896 exclusion phecode
288.11 Neutropenia Hematopoietic 1.12 1 – 1.24 0.0463 441 2646 exclusion phecode
288.2 Elevated white blood cell count Hematopoietic 1.03 0.972 – 1.09 0.343 1702 8532 exclusion phecode
288.3 Eosinophilia Hematopoietic 1.04 0.799 – 1.35 0.776 76 508 exclusion phecode
289 Other diseases of blood and blood-forming organs Hematopoietic 0.974 0.899 – 1.05 0.512 841 4492 exclusion phecode
289.3
Personal history of diseases of blood and
Personal history of diseases of blood and blood-forming organs
 Hematopoietic 0.905 0.814 – 1.01 0.0665 464 2418 exclusion phecode
289.4 Lymphadenitis Hematopoietic 1.01 0.953 – 1.07 0.74 1487 8364 exclusion phecode
289.5 Diseases of spleen Hematopoietic 1.12 0.938 – 1.33 0.214 181 952 exclusion phecode
289.8 Polycythemia, secondary Hematopoietic 1.05 0.838 – 1.32 0.66 96 648 exclusion phecode
289.9 Abnormality of red blood cells Hematopoietic 1.2 1.02 – 1.41 0.0286 188 1035 exclusion phecode
290
Delirium dementia and amnestic and other
Delirium dementia and amnestic and other cognitive disorders
 Mental Disorders 1.08 0.983 – 1.19 0.107 553 2792 exclusion phecode
290.1 Dementias Mental Disorders 1.03 0.889 – 1.2 0.674 227 1179 exclusion phecode
290.11 Alzheimer's disease Mental Disorders 1.08 0.826 – 1.41 0.575 65 357 exclusion phecode
290.12 Dementia with cerebral degenerations Mental Disorders 1.12 0.787 – 1.6 0.527 38 216 exclusion phecode
290.13 Senile dementia Mental Disorders 1.02 0.846 – 1.22 0.864 148 754 exclusion phecode
290.16 Vascular dementia Mental Disorders 1.32 0.871 – 2 0.191 41 180 exclusion phecode
290.2 Delirium due to conditions classified elsewhere Mental Disorders 1.12 0.986 – 1.27 0.0817 314 1762 exclusion phecode
290.3
Other persistent mental disorders due to
Other persistent mental disorders due to conditions classified elsewhere
 Mental Disorders 1.08 0.965 – 1.21 0.179 406 2176 exclusion phecode
291
Other specified nonpsychotic and/or transient
Other specified nonpsychotic and/or transient mental disorders
 Mental Disorders 1.1 1.03 – 1.17 0.00535 1155 6370 exclusion phecode
291.1
Transient mental disorders due to conditions
Transient mental disorders due to conditions classified elsewhere
 Mental Disorders 1.03 0.799 – 1.32 0.831 88 501 exclusion phecode
291.4
Specific nonpsychotic mental disorders due to
Specific nonpsychotic mental disorders due to brain damage
 Mental Disorders 1.04 0.887 – 1.22 0.625 208 1243 exclusion phecode
291.8 Alteration of consciousness Mental Disorders 1.11 1.04 – 1.2 0.00377 928 5119 exclusion phecode
292 Neurological disorders Mental Disorders 1.09 1.04 – 1.15 0.000399 2261 9557 exclusion phecode
292.1 Aphasia/speech disturbance Mental Disorders 1.08 0.997 – 1.18 0.058 688 4848 exclusion phecode
292.11 Aphasia Mental Disorders 1.07 0.936 – 1.23 0.309 264 1596 exclusion phecode
292.12 Symbolic dysfunction Mental Disorders 1.15 0.897 – 1.47 0.27 74 463 exclusion phecode
292.2 Mild cognitive impairment Mental Disorders 1.11 0.937 – 1.3 0.235 192 933 exclusion phecode
292.3 Memory loss Mental Disorders 1.02 0.942 – 1.1 0.648 848 4605 exclusion phecode
292.4 Altered mental status Mental Disorders 1.16 1.08 – 1.24 3.42e-05 1032 5630 exclusion phecode
292.5 Transient alteration of awareness Mental Disorders 1.22 1.04 – 1.44 0.0135 191 1123 exclusion phecode
292.6 Hallucinations Mental Disorders 1.04 0.844 – 1.28 0.71 98 516 exclusion phecode
293 Symptoms involving head and neck Mental Disorders 0.915 0.785 – 1.07 0.252 213 1146 exclusion phecode
293.1
Swelling, mass, or lump in head and neck
Swelling, mass, or lump in head and neck [Space-occupying lesion, intracranial NOS]
 Mental Disorders 1.06 0.999 – 1.12 0.0542 1488 10161 exclusion phecode
295 Schizophrenia and other psychotic disorders Mental Disorders 1.14 1.02 – 1.28 0.0269 416 1580 exclusion phecode
295.1 Schizophrenia Mental Disorders 1.16 0.79 – 1.69 0.455 42 243 exclusion phecode
295.2 Paranoid disorders Mental Disorders 0.999 0.705 – 1.42 0.997 52 200 exclusion phecode
295.3 Psychosis Mental Disorders 1.14 1.01 – 1.3 0.0392 357 1321 exclusion phecode
296 Mood disorders Mental Disorders 1.05 1 – 1.1 0.0348 5235 3832 exclusion phecode
296.1 Bipolar Mental Disorders 1.05 0.944 – 1.17 0.366 479 2098 exclusion phecode
296.2 Depression Mental Disorders 1.05 1 – 1.1 0.04 5072 3828 exclusion phecode
296.22 Major depressive disorder Mental Disorders 1.05 0.998 – 1.1 0.0616 4636 3828 exclusion phecode
297 Suicidal ideation or attempt Mental Disorders 1 0.891 – 1.13 0.975 401 1656 exclusion phecode
297.1 Suicidal ideation Mental Disorders 1.03 0.902 – 1.18 0.654 311 1365 exclusion phecode
297.2 Suicide or self-inflicted injury Mental Disorders 0.961 0.774 – 1.19 0.716 120 492 exclusion phecode
300 Anxiety disorders Mental Disorders 1.04 0.997 – 1.09 0.0691 5364 3829 exclusion phecode
300.1 Anxiety disorder Mental Disorders 1.04 0.991 – 1.09 0.12 5007 3831 exclusion phecode
300.11 Generalized anxiety disorder Mental Disorders 1.04 0.979 – 1.1 0.22 2248 3770 exclusion phecode
300.12 Agorophobia, social phobia, and panic disorder Mental Disorders 1.01 0.918 – 1.12 0.792 604 2145 exclusion phecode
300.13 Phobia Mental Disorders 0.976 0.872 – 1.09 0.668 448 1826 exclusion phecode
300.3 Obsessive-compulsive disorders Mental Disorders 0.991 0.821 – 1.2 0.922 154 612 exclusion phecode
300.4 Dysthymic disorder Mental Disorders 1.05 0.971 – 1.13 0.236 1111 3103 exclusion phecode
300.8 Acute reaction to stress Mental Disorders 0.908 0.784 – 1.05 0.196 278 1029 exclusion phecode
300.9 Posttraumatic stress disorder Mental Disorders 1.02 0.895 – 1.17 0.735 283 1446 exclusion phecode
301 Personality disorders Mental Disorders 1.08 0.913 – 1.27 0.383 204 858 exclusion phecode
301.2 Antisocial/borderline personality disorder Mental Disorders 1 0.788 – 1.27 0.995 106 451 exclusion phecode
302 Sexual and gender identity disorders Mental Disorders 1.06 0.992 – 1.14 0.0851 1419 2615 exclusion phecode
302.1 Decreased libido Mental Disorders 1.02 0.876 – 1.19 0.793 250 953 exclusion phecode
303 Psychogenic and somatoform disorders Mental Disorders 1.04 0.991 – 1.1 0.105 3453 3714 exclusion phecode
303.1 Dissociative disorder Mental Disorders 0.999 0.752 – 1.33 0.995 61 325 exclusion phecode
303.3 Psychogenic disorder Mental Disorders 1.04 0.984 – 1.09 0.174 3349 3682 exclusion phecode
303.31
Gastrointestinal malfunction arising from
Gastrointestinal malfunction arising from mental factors
 Mental Disorders 0.847 0.726 – 0.988 0.0348 227 945 exclusion phecode
303.4 Somatoform disorder Mental Disorders 0.977 0.876 – 1.09 0.676 424 2082 exclusion phecode
304 Adjustment reaction Mental Disorders 1.02 0.959 – 1.08 0.539 1759 3785 exclusion phecode
305.2 Eating disorder Mental Disorders 0.956 0.857 – 1.07 0.416 457 1698 exclusion phecode
306 Other mental disorder Mental Disorders 1 0.924 – 1.09 0.926 852 2718 exclusion phecode
306.1 Mental disorders durring/after pregnancy Mental Disorders 1.09 0.939 – 1.26 0.262 294 729 exclusion phecode
306.9 Tension headache Mental Disorders 0.965 0.85 – 1.09 0.579 346 1520 exclusion phecode
312 Conduct disorders Mental Disorders 1.09 0.883 – 1.34 0.424 124 593 exclusion phecode
312.3 Impulse control disorder Mental Disorders 0.796 0.518 – 1.22 0.299 41 205 exclusion phecode
313 Pervasive developmental disorders Mental Disorders 1.01 0.918 – 1.11 0.851 567 3732 exclusion phecode
313.1 Attention deficit hyperactivity disorder Mental Disorders 0.985 0.891 – 1.09 0.771 493 3315 exclusion phecode
313.2 Tics and stuttering Mental Disorders 0.993 0.631 – 1.56 0.977 28 158 exclusion phecode
313.3 Autism Mental Disorders 1.02 0.666 – 1.58 0.912 29 134 exclusion phecode
315 Develomental delays and disorders Mental Disorders 1.06 0.922 – 1.22 0.419 269 1736 exclusion phecode
315.1 Learning disorder Mental Disorders 1.06 0.735 – 1.53 0.754 39 225 exclusion phecode
315.2 Speech and language disorder Mental Disorders 1.02 0.808 – 1.29 0.869 94 610 exclusion phecode
316 Substance addiction and disorders Mental Disorders 1.02 0.96 – 1.09 0.484 1234 8103 exclusion phecode
316.1 Polyneuropathy due to drugs Mental Disorders 0.884 0.759 – 1.03 0.113 214 1600 exclusion phecode
317 Alcohol-related disorders Mental Disorders 1.02 0.952 – 1.1 0.535 979 5581 exclusion phecode
317.1 Alcoholism Mental Disorders 1.03 0.955 – 1.12 0.416 815 4675 exclusion phecode
317.11 Alcoholic liver damage Mental Disorders 1.18 1 – 1.4 0.0483 184 997 exclusion phecode
318 Tobacco use disorder Mental Disorders 1.11 1.06 – 1.16 1.86e-05 2684 8915 exclusion phecode
320 Meningitis Neurological 1.08 0.889 – 1.31 0.436 128 990 exclusion phecode
323 Encephalitis Neurological 1.01 0.781 – 1.32 0.915 77 488 exclusion phecode
323.8 Encephalitis, non-infectious Neurological 0.982 0.738 – 1.31 0.903 65 395 exclusion phecode
324 Other CNS infection and poliomyelitis Neurological 1.12 0.883 – 1.43 0.344 84 727 exclusion phecode
325
Phlebitis and thrombophlebitis of intracranial
Phlebitis and thrombophlebitis of intracranial venous sinuses
 Neurological 0.701 0.399 – 1.23 0.216 12 156 exclusion phecode
327 Sleep disorders Neurological 1 0.966 – 1.04 0.89 5577 7206 exclusion phecode
327.1 Hypersomnia Neurological 0.98 0.911 – 1.05 0.575 1013 4704 exclusion phecode
327.3 Sleep apnea Neurological 0.986 0.945 – 1.03 0.53 3719 7133 exclusion phecode
327.31 Central/nonobstroctive sleep apnea Neurological 1.02 0.876 – 1.18 0.818 235 1205 exclusion phecode
327.32 Obstructive sleep apnea Neurological 0.983 0.94 – 1.03 0.446 3289 7004 exclusion phecode
327.4 Insomnia Neurological 1.01 0.967 – 1.06 0.556 2658 7079 exclusion phecode
327.41 Organic or persistent insomnia Neurological 1.05 0.956 – 1.15 0.322 674 3020 exclusion phecode
327.5 Parasomnia Neurological 0.973 0.848 – 1.12 0.7 264 1400 exclusion phecode
327.6 Circadian rhythm sleep disorder Neurological 0.945 0.778 – 1.15 0.565 143 744 exclusion phecode
327.7 Sleep related movement disorders Neurological 0.96 0.884 – 1.04 0.336 721 4137 exclusion phecode
327.71 Restless legs syndrome Neurological 0.96 0.877 – 1.05 0.381 594 3684 exclusion phecode
327.72 Sleep related leg cramps Neurological 0.837 0.619 – 1.13 0.247 56 192 exclusion phecode
331 Other cerebral degenerations Neurological 0.961 0.837 – 1.1 0.575 262 1750 exclusion phecode
331.1 Hydrocephalus Neurological 1.06 0.808 – 1.39 0.681 61 635 exclusion phecode
331.9 Cerebral degeneration, unspecified Neurological 0.884 0.749 – 1.04 0.143 194 1054 exclusion phecode
332 Parkinson's disease Neurological 1.03 0.857 – 1.24 0.749 135 1053 exclusion phecode
333
Extrapyramidal disease and abnormal movement
Extrapyramidal disease and abnormal movement disorders
 Neurological 0.937 0.876 – 1 0.0554 1131 7050 exclusion phecode
333.1 Essential tremor Neurological 0.921 0.812 – 1.04 0.202 312 1925 exclusion phecode
333.2 Myoclonus Neurological 0.848 0.637 – 1.13 0.26 66 406 exclusion phecode
333.4 Torsion dystonia Neurological 1 0.827 – 1.22 0.978 128 886 exclusion phecode
333.8 Other degenerative diseases of the basal ganglia Neurological 0.844 0.588 – 1.21 0.355 42 224 exclusion phecode
334 Degenerative disease of the spinal cord Neurological 1.03 0.913 – 1.17 0.616 331 2596 exclusion phecode
334.1 Spinocerebellar disease Neurological 1.18 0.77 – 1.82 0.442 31 191 exclusion phecode
334.2 Anterior horn cell disease Neurological 1.13 0.752 – 1.69 0.559 30 296 exclusion phecode
334.21 Amyotrophic Lateral Sclerosis Neurological 0.911 0.552 – 1.5 0.714 21 183 exclusion phecode
335 Multiple sclerosis Neurological 0.816 0.669 – 0.996 0.0458 129 1053 exclusion phecode
337 Disorders of the autonomic nervous system Neurological 0.974 0.858 – 1.11 0.682 311 2153 exclusion phecode
337.1 Peripheral autonomic neuropathy Neurological 0.984 0.833 – 1.16 0.855 177 1131 exclusion phecode
338 Pain Neurological 1 0.965 – 1.04 0.901 6789 6046 exclusion phecode
338.1 Acute pain Neurological 1.01 0.967 – 1.05 0.724 4892 6005 exclusion phecode
338.2 Chronic pain Neurological 1 0.961 – 1.05 0.901 4282 6018 exclusion phecode
339 Other headache syndromes Neurological 1.02 0.974 – 1.06 0.445 3601 8346 exclusion phecode
340 Migraine Neurological 1.02 0.967 – 1.07 0.541 2613 7344 exclusion phecode
340.1 Migrain with aura Neurological 1.04 0.974 – 1.1 0.265 1526 5682 exclusion phecode
341
Other demyelinating diseases of central nervous
Other demyelinating diseases of central nervous system
 Neurological 0.806 0.596 – 1.09 0.162 54 371 exclusion phecode
342 Hemiplegia Neurological 0.985 0.839 – 1.16 0.857 188 1162 exclusion phecode
343 Infantile cerebral palsy Neurological 0.965 0.638 – 1.46 0.866 25 186 exclusion phecode
344 Other paralytic syndromes Neurological 0.988 0.86 – 1.13 0.86 250 1671 exclusion phecode
345 Epilepsy, recurrent seizures, convulsions Neurological 1.07 0.988 – 1.15 0.097 791 6409 exclusion phecode
345.1 Epilepsy Neurological 1.15 1 – 1.32 0.0446 251 1885 exclusion phecode
345.11 Generalized convulsive epilepsy Neurological 1.13 0.884 – 1.45 0.328 74 547 exclusion phecode
345.12 Partial epilepsy Neurological 1.16 0.978 – 1.37 0.0881 183 1305 exclusion phecode
345.3 Convulsions Neurological 1.06 0.982 – 1.15 0.13 749 6029 exclusion phecode
346
Abnormal findings on study of brain and/or
Abnormal findings on study of brain and/or nervous system
 Neurological 0.895 0.675 – 1.19 0.442 64 465 exclusion phecode
346.1
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of skull and head
 Neurological 1.05 0.958 – 1.15 0.305 604 3718 exclusion phecode
346.2
Nonspecific abnormal results of function study
Nonspecific abnormal results of function study of brain and central nervous system
 Neurological 0.85 0.601 – 1.2 0.356 44 293 exclusion phecode
346.3
Nonspecific abnormal findings in cerebrospinal
Nonspecific abnormal findings in cerebrospinal fluid
 Neurological 0.861 0.579 – 1.28 0.457 32 267 exclusion phecode
347 Cataplexy and narcolepsy Neurological 0.846 0.556 – 1.29 0.435 27 278 exclusion phecode
348 Other conditions of brain Neurological 1.04 0.946 – 1.14 0.433 580 4404 exclusion phecode
348.2 Cerebral edema and compression of brain Neurological 1.04 0.895 – 1.2 0.622 215 2176 exclusion phecode
348.4 Cerebral cysts Neurological 0.953 0.727 – 1.25 0.727 74 604 exclusion phecode
348.7 Coma Neurological 1.01 0.799 – 1.27 0.939 90 585 exclusion phecode
348.8 Encephalopathy, not elsewhere classified Neurological 1.07 0.944 – 1.2 0.304 330 2079 exclusion phecode
348.9 Other conditions of brain, NOS Neurological 1.01 0.927 – 1.09 0.866 708 5735 exclusion phecode
349
Other and unspecified disorders of the nervous
Other and unspecified disorders of the nervous system
 Neurological 0.985 0.867 – 1.12 0.814 302 2315 exclusion phecode
350 Abnormal movement Neurological 1.02 0.971 – 1.07 0.463 2709 9613 exclusion phecode
350.1 Abnormal involuntary movements Neurological 0.995 0.936 – 1.06 0.862 1377 7749 exclusion phecode
350.2 Abnormality of gait Neurological 1.02 0.959 – 1.08 0.574 1590 7524 exclusion phecode
350.3 Lack of coordination Neurological 1.02 0.915 – 1.13 0.757 433 2672 exclusion phecode
350.5 Abnormal reflex Neurological 1.1 0.875 – 1.37 0.426 91 511 exclusion phecode
350.6 Disturbances of sensation of smell and taste Neurological 0.989 0.847 – 1.16 0.891 203 1385 exclusion phecode
351 Other peripheral nerve disorders Neurological 0.987 0.944 – 1.03 0.573 3058 8338 exclusion phecode
352 Disorders of other cranial nerves Neurological 1.08 0.977 – 1.2 0.131 467 4071 exclusion phecode
352.1 Trigeminal nerve disorders [CN5] Neurological 1.15 0.974 – 1.35 0.101 195 1319 exclusion phecode
352.2 Facial nerve disorders [CN7] Neurological 1 0.866 – 1.15 0.997 225 1883 exclusion phecode
353 Nerve root and plexus disorders Neurological 0.983 0.93 – 1.04 0.556 1678 8002 exclusion phecode
353.1 Nerve plexus lesions Neurological 0.974 0.789 – 1.2 0.809 111 919 exclusion phecode
353.2 Nerve root lesions Neurological 0.929 0.654 – 1.32 0.683 39 309 exclusion phecode
355 Complex regional/central pain syndrome Neurological 0.979 0.824 – 1.16 0.812 176 1278 exclusion phecode
355.1 Chronic pain syndrome Neurological 0.962 0.843 – 1.1 0.563 289 2042 exclusion phecode
356 Hereditary and idiopathic peripheral neuropathy Neurological 0.99 0.92 – 1.07 0.783 938 5642 exclusion phecode
357 Inflammatory and toxic neuropathy Neurological 1.05 0.985 – 1.12 0.139 1266 7965 exclusion phecode
358 Myoneural disorders Neurological 1.06 0.955 – 1.18 0.27 440 3131 exclusion phecode
358.1 Myasthenia gravis Neurological 0.696 0.434 – 1.12 0.132 23 270 exclusion phecode
359 Muscular dystrophies and other myopathies Neurological 0.922 0.833 – 1.02 0.119 491 3078 exclusion phecode
359.1 Muscular dystrophies Neurological 0.788 0.466 – 1.33 0.375 19 162 exclusion phecode
359.2 Myopathy Neurological 0.938 0.846 – 1.04 0.225 478 2972 exclusion phecode
360 Disorders of the globe Sense Organs 0.993 0.75 – 1.31 0.959 68 354 exclusion phecode
360.2 Progressive myopia Sense Organs 0.996 0.681 – 1.46 0.984 39 186 exclusion phecode
361 Retinal detachments and defects Sense Organs 0.967 0.861 – 1.09 0.571 380 1863 exclusion phecode
361.1 Retinal detachment with retinal defect Sense Organs 0.983 0.821 – 1.18 0.849 162 779 exclusion phecode
362 Other retinal disorders Sense Organs 1.01 0.954 – 1.07 0.71 1807 5655 exclusion phecode
362.2
Degeneration of macula and posterior pole of
Degeneration of macula and posterior pole of retina
 Sense Organs 0.994 0.925 – 1.07 0.88 1132 3831 exclusion phecode
362.21 Macular degeneration, dry Sense Organs 0.871 0.74 – 1.03 0.0988 229 789 exclusion phecode
362.22 Macular degeneration, wet Sense Organs 0.821 0.63 – 1.07 0.145 74 301 exclusion phecode
362.23 Cystoid macular degeneration of retina Sense Organs 0.993 0.848 – 1.16 0.931 211 936 exclusion phecode
362.26 Macular puckering of retina Sense Organs 0.951 0.859 – 1.05 0.329 539 2268 exclusion phecode
362.27 Drusen (degenerative) of retina Sense Organs 0.935 0.815 – 1.07 0.34 290 1162 exclusion phecode
362.29 Macular degeneration (senile) of retina NOS Sense Organs 1.01 0.937 – 1.09 0.757 981 3503 exclusion phecode
362.3 Other nondiabetic retinopathy Sense Organs 1.06 0.953 – 1.17 0.295 500 2245 exclusion phecode
362.31 Separation of retinal layers Sense Organs 1.07 0.912 – 1.25 0.413 204 1065 exclusion phecode
362.4 Retinal vascular changes and abnomalities Sense Organs 0.938 0.828 – 1.06 0.318 337 1528 exclusion phecode
362.6 Peripheral retinal degenerations Sense Organs 1.04 0.89 – 1.21 0.628 219 1061 exclusion phecode
362.7 Hereditary retinal dystrophies Sense Organs 0.758 0.601 – 0.957 0.0197 89 556 exclusion phecode
362.8 Retinal hemorrhage/ischemia Sense Organs 1.1 0.905 – 1.34 0.34 133 704 exclusion phecode
362.9 Retinal edema Sense Organs 1.05 0.876 – 1.26 0.596 159 836 exclusion phecode
363
Chorioretinal inflammations, scars, and other
Chorioretinal inflammations, scars, and other disorders of choroid
 Sense Organs 0.916 0.791 – 1.06 0.246 245 1222 exclusion phecode
363.3 Chorioretinal scars Sense Organs 0.946 0.794 – 1.13 0.536 173 811 exclusion phecode
364 Corneal opacity and other disorders of cornea Sense Organs 1.02 0.925 – 1.12 0.742 571 2823 exclusion phecode
364.1 Corneal opacity Sense Organs 0.943 0.808 – 1.1 0.455 215 1042 exclusion phecode
364.2 Corneal edema Sense Organs 0.917 0.691 – 1.22 0.55 54 310 exclusion phecode
364.4 Corneal degenerations Sense Organs 1.1 0.934 – 1.29 0.258 195 1143 exclusion phecode
364.41 Keratoconus Sense Organs 1.14 0.797 – 1.64 0.464 38 246 exclusion phecode
364.5 Corneal dystrophy Sense Organs 0.971 0.845 – 1.12 0.676 271 1150 exclusion phecode
364.51 Fuchs' dystrophy Sense Organs 1.05 0.868 – 1.27 0.609 143 640 exclusion phecode
364.9 Cornea replaced by transplant Sense Organs 0.847 0.563 – 1.28 0.426 32 208 exclusion phecode
365 Glaucoma Sense Organs 1.02 0.956 – 1.09 0.531 1212 5453 exclusion phecode
365.1 Open-angle glaucoma Sense Organs 0.918 0.814 – 1.04 0.165 375 1678 exclusion phecode
365.11 Primary open angle glaucoma Sense Organs 0.898 0.762 – 1.06 0.199 211 957 exclusion phecode
365.2 Primary angle-closure glaucoma Sense Organs 0.913 0.749 – 1.11 0.364 130 639 exclusion phecode
366 Cataract Sense Organs 0.962 0.918 – 1.01 0.109 3976 6638 exclusion phecode
366.1 Nonsenile Cataract Sense Organs 0.929 0.738 – 1.17 0.534 114 457 exclusion phecode
366.2 Senile cataract Sense Organs 0.953 0.905 – 1 0.0722 2914 5857 exclusion phecode
367
Disorders of refraction and accommodation
Disorders of refraction and accommodation; blindness and low vision
 Sense Organs 0.987 0.949 – 1.03 0.492 4771 8074 exclusion phecode
367.1 Myopia Sense Organs 0.979 0.935 – 1.02 0.361 2823 7549 exclusion phecode
367.2 Astigmatism Sense Organs 0.953 0.907 – 1 0.0555 2394 7195 exclusion phecode
367.8 Hypermetropia Sense Organs 0.952 0.889 – 1.02 0.156 1186 4312 exclusion phecode
367.9 Blindness and low vision Sense Organs 1.09 0.994 – 1.21 0.0667 560 2732 exclusion phecode
368 Visual disturbances Sense Organs 1.01 0.966 – 1.06 0.636 2629 9873 exclusion phecode
368.1 Amblyopia Sense Organs 1.08 0.941 – 1.23 0.279 290 1766 exclusion phecode
368.2 Diplopia and disorders of binocular vision Sense Organs 0.975 0.878 – 1.08 0.636 457 2724 exclusion phecode
368.3 Anisometropia Sense Organs 1 0.824 – 1.22 0.979 138 575 exclusion phecode
368.4 Visual field defects Sense Organs 1.02 0.918 – 1.12 0.766 496 2811 exclusion phecode
368.9 Subjective visual disturbances Sense Organs 0.978 0.885 – 1.08 0.658 529 2796 exclusion phecode
368.91 Psychophysical visual disturbances Sense Organs 1.22 0.874 – 1.7 0.244 49 283 exclusion phecode
369 Infection of the eye Sense Organs 0.986 0.932 – 1.04 0.624 1730 6635 exclusion phecode
369.2 Eye infection, viral Sense Organs 0.997 0.863 – 1.15 0.967 257 1271 exclusion phecode
369.5 Conjunctivitis, infectious Sense Organs 0.989 0.932 – 1.05 0.725 1513 6015 exclusion phecode
370 Keratitis Sense Organs 0.934 0.856 – 1.02 0.12 702 3197 exclusion phecode
370.1 Corneal ulcer Sense Organs 1.06 0.856 – 1.31 0.597 117 584 exclusion phecode
370.2 Superficial keratitis Sense Organs 0.888 0.775 – 1.02 0.085 301 1326 exclusion phecode
370.3 Keratoconjunctivitis Sense Organs 0.917 0.804 – 1.05 0.195 303 1528 exclusion phecode
370.31 Keratoconjunctivitis sicca Sense Organs 0.927 0.743 – 1.16 0.501 111 419 exclusion phecode
371 Inflammation of the eye Sense Organs 0.971 0.925 – 1.02 0.242 2409 7620 exclusion phecode
371.1 Uveitis, noninfectious or NOS Sense Organs 0.989 0.86 – 1.14 0.876 270 1426 exclusion phecode
371.2 Conjunctivitis, noninfectious Sense Organs 0.903 0.815 – 1 0.0496 507 2378 exclusion phecode
371.21 Allergic conjunctivitis Sense Organs 0.883 0.791 – 0.986 0.0268 426 1999 exclusion phecode
371.3 Inflammation of eyelids Sense Organs 0.976 0.924 – 1.03 0.385 1890 6398 exclusion phecode
371.33 Noninfectious dermatoses of eyelid Sense Organs 0.996 0.768 – 1.29 0.973 86 308 exclusion phecode
372 Disorders of conjunctiva Sense Organs 0.951 0.864 – 1.05 0.306 565 2602 exclusion phecode
374 Other disorders of eyelids Sense Organs 0.987 0.927 – 1.05 0.684 1412 5646 exclusion phecode
374.1 Ectropion or entropion Sense Organs 0.971 0.815 – 1.16 0.747 171 894 exclusion phecode
374.2 Lagophthalmos Sense Organs 1.03 0.771 – 1.39 0.826 60 490 exclusion phecode
374.3 Ptosis of eyelid Sense Organs 0.956 0.865 – 1.06 0.379 516 2531 exclusion phecode
374.6 Dermatochalasis Sense Organs 0.92 0.833 – 1.02 0.103 545 2324 exclusion phecode
375 Disorders of lacrimal system Sense Organs 0.958 0.906 – 1.01 0.139 1931 6195 exclusion phecode
375.1 Dry eyes Sense Organs 0.957 0.907 – 1.01 0.111 2171 6401 exclusion phecode
375.2 Epiphora Sense Organs 1.05 0.887 – 1.24 0.578 183 996 exclusion phecode
376 Disorders of the orbit Sense Organs 0.901 0.732 – 1.11 0.328 107 794 exclusion phecode
377 Disorders of optic nerve and visual pathways Sense Organs 1.08 0.959 – 1.21 0.209 375 2109 exclusion phecode
377.1 Optic atrophy Sense Organs 0.979 0.813 – 1.18 0.823 151 719 exclusion phecode
377.3 Optic neuritis/neuropathy Sense Organs 1.04 0.888 – 1.21 0.654 216 1313 exclusion phecode
378
Strabismus and other disorders of binocular eye
Strabismus and other disorders of binocular eye movements
 Sense Organs 1.06 0.955 – 1.17 0.291 510 2831 exclusion phecode
378.1 Strabismus (not specified as paralytic) Sense Organs 1.01 0.893 – 1.13 0.92 345 1901 exclusion phecode
378.2 Nystagmus and other irregular eye movements Sense Organs 1.21 0.917 – 1.6 0.177 75 386 exclusion phecode
378.5 Paralytic strabismus Sense Organs 1.07 0.867 – 1.32 0.521 105 756 exclusion phecode
379 Other disorders of eye Sense Organs 0.992 0.945 – 1.04 0.763 2703 7055 exclusion phecode
379.1 Scleritis and episcleritis Sense Organs 1.06 0.835 – 1.36 0.619 87 471 exclusion phecode
379.2 Disorders of vitreous body Sense Organs 0.977 0.925 – 1.03 0.414 2074 5506 exclusion phecode
379.3 Aphakia and other disorders of lens Sense Organs 1.22 0.923 – 1.6 0.164 65 300 exclusion phecode
379.4 Anomalies of pupillary function Sense Organs 0.984 0.797 – 1.21 0.878 116 698 exclusion phecode
379.5 Disorders of iris and ciliary body Sense Organs 1.02 0.844 – 1.22 0.863 148 752 exclusion phecode
379.51 Pigmentary iris degeneration Sense Organs 1.13 0.78 – 1.64 0.519 48 157 exclusion phecode
379.9 Pain, swelling or discharge of eye Sense Organs 0.942 0.854 – 1.04 0.227 543 2713 exclusion phecode
380 Disorders of external ear Sense Organs 0.961 0.9 – 1.03 0.229 1274 5381 exclusion phecode
380.1 Otitis externa Sense Organs 1.03 0.946 – 1.12 0.503 732 3942 exclusion phecode
380.4 Impacted cerumen Sense Organs 0.947 0.892 – 1 0.0702 1584 6213 exclusion phecode
381 Otitis media and Eustachian tube disorders Sense Organs 0.987 0.938 – 1.04 0.62 2027 9020 exclusion phecode
381.1 Otitis media Sense Organs 1.01 0.955 – 1.08 0.641 1370 7447 exclusion phecode
381.11 Suppurative and unspecified otitis media Sense Organs 1.02 0.956 – 1.09 0.52 1143 6382 exclusion phecode
381.2 Eustachian tube disorders Sense Organs 0.967 0.9 – 1.04 0.358 1033 4791 exclusion phecode
381.3 Mastoiditis & related conditions Sense Organs 0.827 0.589 – 1.16 0.271 41 379 exclusion phecode
381.9 Otorrhea Sense Organs 1.01 0.83 – 1.23 0.905 120 862 exclusion phecode
382 Otalgia Sense Organs 0.946 0.879 – 1.02 0.141 964 4902 exclusion phecode
383 Otosclerosis Sense Organs 1.26 0.894 – 1.77 0.188 41 318 exclusion phecode
384 Other disorders of tympanic membrane Sense Organs 1.09 0.926 – 1.28 0.303 195 1249 exclusion phecode
384.1 Myringitis Sense Organs 0.694 0.386 – 1.25 0.223 16 122 exclusion phecode
384.4 Perforation of tympanic membrane Sense Organs 1 0.835 – 1.2 0.985 154 961 exclusion phecode
385 Other disorders of middle ear and mastoid Sense Organs 0.998 0.822 – 1.21 0.982 122 1001 exclusion phecode
385.3 Cholesteatoma Sense Organs 0.974 0.74 – 1.28 0.849 57 590 exclusion phecode
385.5
Tympanosclerosis and middle ear disease related
Tympanosclerosis and middle ear disease related to otitis media
 Sense Organs 1.7 1.16 – 2.47 0.00613 35 281 exclusion phecode
386
Vertiginous syndromes and other disorders of
Vertiginous syndromes and other disorders of vestibular system
 Sense Organs 0.966 0.895 – 1.04 0.37 895 4574 exclusion phecode
386.1 Meniere's disease Sense Organs 0.941 0.78 – 1.13 0.523 134 804 exclusion phecode
386.2 Peripheral or central vertigo Sense Organs 0.978 0.902 – 1.06 0.601 776 3923 exclusion phecode
386.21 Central origin vertigo Sense Organs 0.985 0.896 – 1.08 0.755 571 3010 exclusion phecode
386.3 Labyrinthitis Sense Organs 0.961 0.881 – 1.05 0.368 688 3711 exclusion phecode
386.9
Dizziness and giddiness (Light-headedness and
Dizziness and giddiness (Light-headedness and vertigo)
 Sense Organs 1.01 0.963 – 1.05 0.81 3312 9190 exclusion phecode
388 Other disorders of ear Sense Organs 0.966 0.869 – 1.07 0.516 466 2459 exclusion phecode
389 Hearing loss Sense Organs 0.971 0.93 – 1.01 0.187 3399 9140 exclusion phecode
389.1 Sensorineural hearing loss Sense Organs 0.951 0.901 – 1 0.0691 2003 7059 exclusion phecode
389.2 Conductive hearing loss Sense Organs 0.913 0.806 – 1.03 0.15 335 2149 exclusion phecode
389.3 Degenerative and vascular disorders of ear Sense Organs 0.733 0.583 – 0.921 0.00769 107 465 exclusion phecode
389.4 Tinnitus Sense Organs 0.946 0.884 – 1.01 0.11 1131 5544 exclusion phecode
389.5 Disorders of acoustic nerve Sense Organs 0.907 0.682 – 1.21 0.5 60 307 exclusion phecode
394 Rheumatic disease of the heart valves Circulatory System 0.994 0.916 – 1.08 0.893 818 3284 exclusion phecode
394.1 Mitral valve stenosis and aortic valve stenosis Circulatory System 1.03 0.88 – 1.22 0.683 210 811 exclusion phecode
394.2 Mitral valve disease Circulatory System 0.995 0.866 – 1.14 0.942 272 1093 exclusion phecode
394.3 Aortic valve disease Circulatory System 0.985 0.796 – 1.22 0.888 118 375 exclusion phecode
394.4 Acute rheumatic heart disease Circulatory System 0.963 0.611 – 1.52 0.87 27 130 exclusion phecode
394.7 Disease of tricuspid valve Circulatory System 1.04 0.915 – 1.18 0.539 327 1337 exclusion phecode
395 Heart valve disorders Circulatory System 1.01 0.955 – 1.07 0.76 1922 7036 exclusion phecode
395.1 Nonrheumatic mitral valve disorders Circulatory System 0.996 0.927 – 1.07 0.903 1079 5100 exclusion phecode
395.2 Nonrheumatic aortic valve disorders Circulatory System 1.03 0.954 – 1.1 0.49 1082 4111 exclusion phecode
395.3 Nonrheumatic tricuspid valve disorders Circulatory System 0.972 0.847 – 1.12 0.685 289 1201 exclusion phecode
395.4 Nonrheumatic pulmonary valve disorders Circulatory System 0.99 0.729 – 1.35 0.951 54 257 exclusion phecode
395.6 Heart valve replaced Circulatory System 1.08 0.981 – 1.18 0.12 629 2451 exclusion phecode
396 Abnormal heart sounds Circulatory System 1.02 0.973 – 1.08 0.361 2065 8592 exclusion phecode
401 Hypertension Circulatory System 1.03 0.986 – 1.07 0.194 6848 5981 exclusion phecode
401.1 Essential hypertension Circulatory System 1.03 0.986 – 1.07 0.193 6794 5979 exclusion phecode
401.2 Hypertensive heart and/or renal disease Circulatory System 1.04 0.967 – 1.12 0.299 1422 3750 exclusion phecode
401.21 Hypertensive heart disease Circulatory System 1.03 0.913 – 1.16 0.639 422 1652 exclusion phecode
401.22 Hypertensive chronic kidney disease Circulatory System 1.03 0.951 – 1.12 0.455 981 3337 exclusion phecode
401.3 Other hypertensive complications Circulatory System 0.984 0.914 – 1.06 0.677 1128 4121 exclusion phecode
411 Ischemic Heart Disease Circulatory System 1.09 1.04 – 1.15 0.000176 3383 7389 exclusion phecode
411.1 Unstable angina (intermediate coronary syndrome) Circulatory System 1.14 1.02 – 1.27 0.0201 456 2008 exclusion phecode
411.2 Myocardial infarction Circulatory System 1.16 1.09 – 1.25 1.18e-05 1231 5043 exclusion phecode
411.3 Angina pectoris Circulatory System 1.13 1.05 – 1.21 0.00107 1157 4254 exclusion phecode
411.4 Coronary atherosclerosis Circulatory System 1.1 1.05 – 1.16 0.000177 2954 6674 exclusion phecode
411.41 Aneurysm and dissection of heart Circulatory System 0.903 0.683 – 1.19 0.475 80 331 exclusion phecode
411.8
Other chronic ischemic heart disease
Other chronic ischemic heart disease, unspecified
 Circulatory System 1.13 1.07 – 1.19 1.89e-05 2371 6120 exclusion phecode
411.9
Other acute and subacute forms of ischemic
Other acute and subacute forms of ischemic heart disease
 Circulatory System 1.1 0.944 – 1.28 0.22 216 1016 exclusion phecode
414 Other forms of chronic heart disease Circulatory System 1.06 1 – 1.13 0.0501 1494 5313 exclusion phecode
414.2 ASCVD Circulatory System 1.01 0.895 – 1.13 0.905 384 1631 exclusion phecode
415 Pulmonary heart disease Circulatory System 1.02 0.958 – 1.09 0.525 1274 7774 exclusion phecode
415.1 Acute pulmonary heart disease Circulatory System 1 0.92 – 1.09 0.946 640 4863 exclusion phecode
415.11 Pulmonary embolism and infarction, acute Circulatory System 1.01 0.926 – 1.1 0.813 637 4847 exclusion phecode
415.2 Chronic pulmonary heart disease Circulatory System 1.04 0.964 – 1.13 0.291 812 4617 exclusion phecode
415.21 Primary pulmonary hypertension Circulatory System 1.04 0.914 – 1.18 0.563 306 1862 exclusion phecode
416 Cardiomegaly Circulatory System 1.05 0.962 – 1.15 0.264 625 3280 exclusion phecode
418 Nonspecific chest pain Circulatory System 1.04 1.01 – 1.08 0.0231 6044 6754 exclusion phecode
418.1 Precordial pain Circulatory System 1.03 0.947 – 1.12 0.477 768 2804 exclusion phecode
420 Carditis Circulatory System 0.996 0.918 – 1.08 0.924 760 4075 exclusion phecode
420.1 Myocarditis Circulatory System 0.961 0.69 – 1.34 0.814 44 261 exclusion phecode
420.2 Pericarditis Circulatory System 1 0.899 – 1.12 0.942 403 2168 exclusion phecode
420.21 Acute pericarditis Circulatory System 0.962 0.76 – 1.22 0.748 90 468 exclusion phecode
420.22 Chronic pericarditis Circulatory System 0.918 0.696 – 1.21 0.541 64 307 exclusion phecode
420.3 Endocarditis Circulatory System 0.984 0.878 – 1.1 0.787 384 1969 exclusion phecode
425 Cardiomyopathy Circulatory System 1.05 0.976 – 1.13 0.192 969 5036 exclusion phecode
425.1 Primary/intrinsic cardiomyopathies Circulatory System 1.05 0.97 – 1.13 0.243 931 4846 exclusion phecode
425.11 Hypertrophic obstructive cardiomyopathy Circulatory System 0.957 0.765 – 1.2 0.696 96 507 exclusion phecode
425.12 Other hypertrophic cardiomyopathy Circulatory System 1.03 0.815 – 1.3 0.813 85 514 exclusion phecode
425.2 Secondary/extrinsic cardiomyopathies Circulatory System 0.863 0.72 – 1.03 0.111 167 789 exclusion phecode
425.8 Other cardiomyopathy Circulatory System 1.05 0.738 – 1.51 0.77 38 229 exclusion phecode
426 Cardiac conduction disorders Circulatory System 1.05 0.999 – 1.1 0.0538 5139 4815 exclusion phecode
426.2 Atrioventricular [AV] block Circulatory System 1.01 0.921 – 1.1 0.855 906 1859 exclusion phecode
426.21 First degree AV block Circulatory System 0.989 0.89 – 1.1 0.842 603 1395 exclusion phecode
426.22 Mobitz II AV block Circulatory System 0.882 0.562 – 1.38 0.583 36 93 exclusion phecode
426.23 Second degree AV block Circulatory System 1.2 0.954 – 1.51 0.12 109 298 exclusion phecode
426.24 Atrioventricular block, complete Circulatory System 1.06 0.896 – 1.24 0.518 259 589 exclusion phecode
426.25 Other heart block Circulatory System 0.981 0.757 – 1.27 0.882 101 268 exclusion phecode
426.3 Bundle branch block Circulatory System 1.03 0.945 – 1.12 0.531 971 2342 exclusion phecode
426.31 Right bundle branch block Circulatory System 1.05 0.95 – 1.17 0.327 587 1739 exclusion phecode
426.32 Left bundle branch block Circulatory System 0.964 0.858 – 1.08 0.533 439 1292 exclusion phecode
426.4 Anomalous atrioventricular excitation Circulatory System 0.938 0.595 – 1.48 0.783 27 121 exclusion phecode
426.7 Abnormal electrocardiogram [ECG] [EKG] Circulatory System 1.05 0.998 – 1.1 0.0627 4633 4791 exclusion phecode
426.8 Other cardiac conduction disorders Circulatory System 1.02 0.892 – 1.16 0.786 317 1193 exclusion phecode
426.9 Cardiac pacemaker/device in situ Circulatory System 1.06 0.962 – 1.16 0.247 739 1863 exclusion phecode
426.91 Cardiac pacemaker in situ Circulatory System 1.01 0.896 – 1.13 0.89 486 1287 exclusion phecode
426.92 Cardiac defibrillator in situ Circulatory System 1.05 0.928 – 1.19 0.437 394 1125 exclusion phecode
427 Cardiac dysrhythmias Circulatory System 1.04 0.993 – 1.08 0.1 6779 4904 exclusion phecode
427.1 Paroxysmal tachycardia, unspecified Circulatory System 1.06 0.984 – 1.14 0.127 1162 3225 exclusion phecode
427.11 Paroxysmal supraventricular tachycardia Circulatory System 1.11 1.01 – 1.21 0.0284 730 2485 exclusion phecode
427.12 Paroxysmal ventricular tachycardia Circulatory System 1.01 0.914 – 1.12 0.816 607 1619 exclusion phecode
427.2 Atrial fibrillation and flutter Circulatory System 1.02 0.959 – 1.09 0.485 2090 3331 exclusion phecode
427.21 Atrial fibrillation Circulatory System 1.03 0.962 – 1.1 0.411 2042 3261 exclusion phecode
427.22 Atrial flutter Circulatory System 0.974 0.888 – 1.07 0.574 802 1755 exclusion phecode
427.3 Other specified cardiac dysrhythmias Circulatory System 1.05 1 – 1.11 0.0337 3742 4799 exclusion phecode
427.4 Cardiac arrest and ventricular fibrillation Circulatory System 0.95 0.816 – 1.1 0.504 256 887 exclusion phecode
427.41 Ventricular fibrillation and flutter Circulatory System 1.01 0.8 – 1.27 0.937 118 387 exclusion phecode
427.42 Cardiac arrest Circulatory System 0.996 0.837 – 1.18 0.96 195 672 exclusion phecode
427.5 Arrhythmia (cardiac) NOS Circulatory System 1 0.95 – 1.06 0.932 2867 4781 exclusion phecode
427.6 Premature beats Circulatory System 1.02 0.947 – 1.1 0.588 1186 2978 exclusion phecode
427.61 Supraventricular premature beats Circulatory System 0.993 0.869 – 1.13 0.913 335 1114 exclusion phecode
427.7 Tachycardia NOS Circulatory System 1.06 0.999 – 1.12 0.0535 2066 4823 exclusion phecode
427.8 Sinoatrial node dysfunction (Bradycardia) Circulatory System 1.03 0.913 – 1.16 0.652 483 1208 exclusion phecode
427.9 Palpitations Circulatory System 0.986 0.934 – 1.04 0.606 2456 4760 exclusion phecode
428 Congestive heart failure; nonhypertensive Circulatory System 1.11 1.04 – 1.18 0.000809 1826 4870 exclusion phecode
428.1 Congestive heart failure (CHF) NOS Circulatory System 1.1 1.03 – 1.17 0.00424 1562 4566 exclusion phecode
428.2 Heart failure NOS Circulatory System 1.12 1.05 – 1.19 0.000693 1543 4387 exclusion phecode
428.3
Heart failure with reduced EF [Systolic or
Heart failure with reduced EF [Systolic or combined heart failure]
 Circulatory System 1.12 1.03 – 1.22 0.00756 864 2776 exclusion phecode
428.4
Heart failure with preserved EF [Diastolic
Heart failure with preserved EF [Diastolic heart failure]
 Circulatory System 1.05 0.968 – 1.15 0.226 780 2604 exclusion phecode
429
Ill-defined descriptions and complications of
Ill-defined descriptions and complications of heart disease
 Circulatory System 1.05 1.01 – 1.09 0.0162 5471 6941 exclusion phecode
429.1 Heart transplant/surgery Circulatory System 1.08 0.988 – 1.19 0.0898 638 2227 exclusion phecode
429.2 Abnormal function study of cardiovascular system Circulatory System 1.07 1.01 – 1.12 0.0121 2857 6330 exclusion phecode
429.3 Symptoms involving cardiovascular system Circulatory System 1.05 1.01 – 1.1 0.0206 4323 6938 exclusion phecode
429.9 Cardiac complications, not elsewhere classified Circulatory System 1.03 0.908 – 1.16 0.66 353 1289 exclusion phecode
430 Intracranial hemorrhage Circulatory System 1.15 1.01 – 1.31 0.0319 291 1973 exclusion phecode
430.1 Subarachnoid hemorrhage Circulatory System 1.17 0.94 – 1.46 0.16 108 653 exclusion phecode
430.2 Intracerebral hemorrhage Circulatory System 1.18 0.971 – 1.44 0.0961 131 912 exclusion phecode
430.3 Subdural hemorrhage Circulatory System 0.997 0.811 – 1.23 0.975 102 673 exclusion phecode
433 Cerebrovascular disease Circulatory System 1.08 1.03 – 1.14 0.00363 2029 8462 exclusion phecode
433.1 Occlusion and stenosis of precerebral arteries Circulatory System 1.19 1.1 – 1.29 9.47e-06 883 4153 exclusion phecode
433.11
Occlusion of cerebral arteries, with cerebral
Occlusion of cerebral arteries, with cerebral infarction
 Circulatory System 1.32 1.08 – 1.62 0.00702 121 642 exclusion phecode
433.12 Cerebral atherosclerosis Circulatory System 1.74 1.19 – 2.53 0.00411 42 205 exclusion phecode
433.2 Occlusion of cerebral arteries Circulatory System 1.12 1.03 – 1.2 0.00547 838 5599 exclusion phecode
433.21
Cerebral artery occlusion, with cerebral
Cerebral artery occlusion, with cerebral infarction
 Circulatory System 1.11 1.02 – 1.2 0.0105 811 5421 exclusion phecode
433.3 Cerebral ischemia Circulatory System 1.04 0.968 – 1.11 0.294 1082 5928 exclusion phecode
433.31 Transient cerebral ischemia Circulatory System 1.02 0.947 – 1.1 0.597 930 5377 exclusion phecode
433.5 Cerebral aneurysm Circulatory System 1.06 0.881 – 1.27 0.553 147 1270 exclusion phecode
433.6 Acute, but ill-defined cerebrovascular disease Circulatory System 1.08 0.932 – 1.25 0.308 242 1176 exclusion phecode
433.8 Late effects of cerebrovascular disease Circulatory System 1.12 0.989 – 1.27 0.0735 331 1700 exclusion phecode
440 Atherosclerosis Circulatory System 1.07 0.997 – 1.14 0.0618 1148 4554 exclusion phecode
440.1 Atherosclerosis of renal artery Circulatory System 1.12 0.888 – 1.41 0.34 95 518 exclusion phecode
440.2 Atherosclerosis of the extremities Circulatory System 1.02 0.935 – 1.11 0.652 670 3157 exclusion phecode
440.21
Atherosclerosis of native arteries of the
Atherosclerosis of native arteries of the extremities with ulceration or gangrene
 Circulatory System 1.01 0.813 – 1.24 0.963 122 656 exclusion phecode
440.22
Atherosclerosis of native arteries of the
Atherosclerosis of native arteries of the extremities with intermittent claudication
 Circulatory System 1 0.907 – 1.11 0.96 501 2322 exclusion phecode
440.9 Atherosclerosis of aorta Circulatory System 1.1 0.986 – 1.23 0.0874 432 1846 exclusion phecode
441 Vascular insufficiency of intestine Circulatory System 1.05 0.911 – 1.22 0.484 246 1241 exclusion phecode
441.1 Acute vascular insufficiency of intestine Circulatory System 1.31 1.06 – 1.62 0.0114 128 591 exclusion phecode
441.2 Chronic vascular insufficiency of intestine Circulatory System 0.947 0.728 – 1.23 0.687 76 365 exclusion phecode
442 Other aneurysm Circulatory System 1.04 0.972 – 1.11 0.248 1199 4857 exclusion phecode
442.1 Aortic aneurysm Circulatory System 1.02 0.95 – 1.11 0.53 960 3668 exclusion phecode
442.11 Abdominal aortic aneurysm Circulatory System 1.03 0.932 – 1.14 0.545 505 2277 exclusion phecode
442.2 Aneurysm of iliac artery Circulatory System 1.18 0.929 – 1.51 0.173 92 399 exclusion phecode
442.3 Aneurysm of artery of lower extremity Circulatory System 1.22 0.914 – 1.64 0.174 63 362 exclusion phecode
442.4 Arterial dissection Circulatory System 1.05 0.814 – 1.35 0.708 87 377 exclusion phecode
442.8 Aneurysm of other specified artery Circulatory System 0.928 0.779 – 1.11 0.405 166 896 exclusion phecode
443 Peripheral vascular disease Circulatory System 1.01 0.946 – 1.08 0.792 1301 5892 exclusion phecode
443.1 Raynaud's syndrome Circulatory System 0.905 0.804 – 1.02 0.0935 366 1861 exclusion phecode
443.7
Peripheral angiopathy in diseases classified
Peripheral angiopathy in diseases classified elsewhere
 Circulatory System 1 0.806 – 1.24 0.994 105 599 exclusion phecode
443.8 Other specified peripheral vascular diseases Circulatory System 1.01 0.941 – 1.08 0.791 1046 5210 exclusion phecode
443.9 Peripheral vascular disease, unspecified Circulatory System 1.03 0.96 – 1.11 0.378 949 4409 exclusion phecode
444 Arterial embolism and thrombosis Circulatory System 1.07 0.952 – 1.21 0.249 345 1959 exclusion phecode
444.1
Arterial embolism and thrombosis of lower
Arterial embolism and thrombosis of lower extremity artery
 Circulatory System 0.995 0.819 – 1.21 0.956 134 704 exclusion phecode
444.2 Embolism and thrombosis of abdominal aorta Circulatory System 1.33 1.01 – 1.75 0.0447 73 332 exclusion phecode
446 Polyarteritis nodosa and allied conditions Circulatory System 0.997 0.84 – 1.18 0.976 190 1089 exclusion phecode
446.4 Wegener's granulomatosis Circulatory System 1.08 0.745 – 1.57 0.684 32 252 exclusion phecode
446.5 Giant cell arteritis Circulatory System 0.834 0.549 – 1.27 0.394 35 162 exclusion phecode
446.9 Arteritis NOS Circulatory System 0.916 0.735 – 1.14 0.437 119 737 exclusion phecode
447 Other disorders of arteries and arterioles Circulatory System 1.04 0.973 – 1.11 0.242 1194 5232 exclusion phecode
447.1 Stricture of artery Circulatory System 1.13 0.976 – 1.32 0.101 221 1118 exclusion phecode
447.7 Aortic ectasia Circulatory System 1 0.9 – 1.12 0.953 462 1791 exclusion phecode
448 Disease of capillaries Circulatory System 0.903 0.829 – 0.985 0.0207 683 3078 exclusion phecode
450 Noninfectious disorders of lymphatic channels Circulatory System 1.03 0.955 – 1.12 0.409 755 5792 exclusion phecode
451 Phlebitis and thrombophlebitis Circulatory System 0.956 0.841 – 1.09 0.484 346 1463 exclusion phecode
451.2
Phlebitis and thrombophlebitis of lower
Phlebitis and thrombophlebitis of lower extremities
 Circulatory System 0.812 0.649 – 1.02 0.0691 120 521 exclusion phecode
452 Other venous embolism and thrombosis Circulatory System 1.04 0.984 – 1.11 0.16 1694 6003 exclusion phecode
452.1 Iatrogenic pulmonary embolism and infarction Circulatory System 0.891 0.722 – 1.1 0.284 116 555 exclusion phecode
452.2 Deep vein thrombosis [DVT] Circulatory System 1.04 0.97 – 1.12 0.263 1072 5350 exclusion phecode
452.8 Postphlebitic syndrome Circulatory System 0.812 0.583 – 1.13 0.221 46 275 exclusion phecode
453 Chronic venous hypertension Circulatory System 0.847 0.689 – 1.04 0.116 133 522 exclusion phecode
454 Varicose veins Circulatory System 0.997 0.934 – 1.06 0.923 1344 5084 exclusion phecode
454.1 Varicose veins of lower extremity Circulatory System 0.977 0.912 – 1.05 0.498 1209 4472 exclusion phecode
454.11 Varicose veins of lower extremity, symptomtic Circulatory System 0.922 0.849 – 1 0.0541 844 3187 exclusion phecode
455 Hemorrhoids Circulatory System 1.03 0.982 – 1.08 0.229 3249 6253 exclusion phecode
456 Chronic venous insufficiency [CVI] Circulatory System 0.982 0.923 – 1.04 0.555 1556 5256 exclusion phecode
457
Encounter for long-term (current) use of
Encounter for long-term (current) use of anticoagulants, antithrombotics, aspirin
 Circulatory System 1.16 1.07 – 1.27 0.000551 769 2915 exclusion phecode
457.2
Encounter for long-term (current) use of
Encounter for long-term (current) use of antiplatelets/antithrombotics
 Circulatory System 1.43 1.17 – 1.75 0.000454 123 593 exclusion phecode
457.3 Encounter for long-term (current) use of aspirin Circulatory System 1.11 1.02 – 1.22 0.0186 720 2795 exclusion phecode
458 Hypotension Circulatory System 1.09 1.04 – 1.15 0.000681 2208 7635 exclusion phecode
458.1 Orthostatic hypotension Circulatory System 0.973 0.889 – 1.07 0.563 647 3034 exclusion phecode
458.2 Iatrogenic hypotension Circulatory System 1.16 1.05 – 1.29 0.0037 499 2506 exclusion phecode
458.9 Hypotension NOS Circulatory System 1.09 1.04 – 1.15 0.00132 1990 7374 exclusion phecode
459 Other disorders of circulatory system Circulatory System 1.03 0.988 – 1.08 0.152 2976 8299 exclusion phecode
459.1 Hemorrhage NOS Circulatory System 1.01 0.899 – 1.13 0.873 390 2048 exclusion phecode
459.7 Blood vessel replaced Circulatory System 1.08 0.977 – 1.2 0.134 497 2829 exclusion phecode
459.9 Circulatory disease NEC Circulatory System 1.03 0.98 – 1.08 0.254 2543 7984 exclusion phecode
464 Acute sinusitis Respiratory 0.958 0.913 – 1.01 0.0874 2785 6132 exclusion phecode
465
Acute upper respiratory infections of multiple
Acute upper respiratory infections of multiple or unspecified sites
 Respiratory 0.974 0.937 – 1.01 0.183 5381 6826 exclusion phecode
465.2 Acute pharyngitis Respiratory 0.981 0.935 – 1.03 0.418 3011 6127 exclusion phecode
465.4 Acute laryngitis and tracheitis Respiratory 0.963 0.823 – 1.13 0.642 234 869 exclusion phecode
470 Septal Deviations/Turbinate Hypertrophy Respiratory 0.959 0.878 – 1.05 0.361 671 3410 exclusion phecode
471 Nasal polyps Respiratory 1.02 0.874 – 1.19 0.803 205 1217 exclusion phecode
472 Chronic pharyngitis and nasopharyngitis Respiratory 0.944 0.873 – 1.02 0.144 926 3660 exclusion phecode
473 Diseases of the larynx and vocal cords Respiratory 1.03 0.962 – 1.1 0.391 1099 5028 exclusion phecode
473.1 Chronic laryngitis Respiratory 1.01 0.667 – 1.54 0.948 35 138 exclusion phecode
473.3 Paralysis/spasm of vocal cords or larynx Respiratory 1.1 0.95 – 1.27 0.201 225 1243 exclusion phecode
473.4 Voice disturbance Respiratory 1.05 0.971 – 1.13 0.228 866 4331 exclusion phecode
474 Acute and chronic tonsillitis Respiratory 0.976 0.864 – 1.1 0.694 363 1548 exclusion phecode
474.1 Acute tonsillitis Respiratory 0.915 0.743 – 1.13 0.399 139 588 exclusion phecode
474.2 Chronic tonsillitis and adenoiditis Respiratory 0.984 0.857 – 1.13 0.817 279 1216 exclusion phecode
475 Chronic sinusitis Respiratory 0.995 0.941 – 1.05 0.85 2008 5606 exclusion phecode
475.9 Postnasal drip Respiratory 0.955 0.859 – 1.06 0.395 504 1990 exclusion phecode
476 Allergic rhinitis Respiratory 0.97 0.931 – 1.01 0.143 5166 5672 exclusion phecode
477 Epistaxis or throat hemorrhage Respiratory 1.1 0.993 – 1.21 0.0688 564 2324 exclusion phecode
478 Throat pain Respiratory 1.12 0.942 – 1.32 0.203 181 851 exclusion phecode
479 Other upper respiratory disease Respiratory 0.972 0.924 – 1.02 0.282 2373 5650 exclusion phecode
480 Pneumonia Respiratory 1.06 1.01 – 1.11 0.0245 2453 8531 exclusion phecode
480.1 Bacterial pneumonia Respiratory 1.11 1.01 – 1.23 0.0347 547 2682 exclusion phecode
480.11 Pneumococcal pneumonia Respiratory 1.01 0.88 – 1.15 0.941 294 1327 exclusion phecode
480.12 Pseudomonal pneumonia Respiratory 1.2 0.916 – 1.57 0.187 75 346 exclusion phecode
480.13 MRSA pneumonia Respiratory 1.21 0.874 – 1.68 0.249 46 294 exclusion phecode
480.2 Viral pneumonia Respiratory 1.23 0.979 – 1.55 0.0748 97 497 exclusion phecode
480.3 Pneumonia due to fungus (mycoses) Respiratory 1.24 0.956 – 1.6 0.106 83 375 exclusion phecode
480.5 Bronchopneumonia and lung abscess Respiratory 1.1 0.794 – 1.54 0.556 50 302 exclusion phecode
481 Influenza Respiratory 0.969 0.889 – 1.06 0.472 748 3491 exclusion phecode
483 Acute bronchitis and bronchiolitis Respiratory 0.978 0.927 – 1.03 0.419 1958 7289 exclusion phecode
495 Asthma Respiratory 1 0.956 – 1.05 0.991 2953 8434 exclusion phecode
495.1 Chronic obstructive asthma Respiratory 0.956 0.804 – 1.14 0.608 165 1056 exclusion phecode
495.11 Chronic obstructive asthma with exacerbation Respiratory 0.745 0.534 – 1.04 0.0819 46 250 exclusion phecode
495.2 Asthma with exacerbation Respiratory 0.986 0.911 – 1.07 0.725 836 4303 exclusion phecode
496 Chronic airway obstruction Respiratory 1.02 0.964 – 1.09 0.456 1529 7141 exclusion phecode
496.1 Emphysema Respiratory 1.08 0.986 – 1.17 0.0997 662 4758 exclusion phecode
496.2 Chronic bronchitis Respiratory 1.02 0.956 – 1.09 0.518 1155 6695 exclusion phecode
496.21 Obstructive chronic bronchitis Respiratory 1.02 0.952 – 1.1 0.556 1049 6391 exclusion phecode
496.3 Bronchiectasis Respiratory 1.07 0.928 – 1.23 0.353 244 1486 exclusion phecode
497 Bronchitis Respiratory 0.995 0.926 – 1.07 0.888 992 5243 exclusion phecode
498 Acute bronchospasm Respiratory 0.972 0.841 – 1.12 0.694 262 1344 exclusion phecode
499 Cystic fibrosis Respiratory 1.04 0.803 – 1.34 0.776 88 484 exclusion phecode
500 Lung disease due to external agents Respiratory 1.07 0.912 – 1.25 0.423 204 1355 exclusion phecode
500.1 Extrinsic allergic alveolitis Respiratory 0.972 0.684 – 1.38 0.873 39 248 exclusion phecode
500.2 Pneumoconiosis Respiratory 1.25 0.831 – 1.87 0.287 34 169 exclusion phecode
501 Pneumonitis due to inhalation of food or vomitus Respiratory 1.14 0.99 – 1.3 0.0693 266 1419 exclusion phecode
502 Postinflammatory pulmonary fibrosis Respiratory 1.15 1.02 – 1.3 0.025 341 1970 exclusion phecode
503 Pulmonary congestion and hypostasis Respiratory 1.19 1.06 – 1.34 0.00323 385 1992 exclusion phecode
504 Other alveolar and parietoalveolar pneumonopathy Respiratory 1.13 0.982 – 1.31 0.0879 249 1493 exclusion phecode
504.1 Idiopathic fibrosing alveolitis Respiratory 1.13 0.926 – 1.37 0.233 135 777 exclusion phecode
505 Other pulmonary inflamation or edema Respiratory 1.09 1.01 – 1.19 0.0342 774 3904 exclusion phecode
506 Empyema and pneumothorax Respiratory 1.13 1.06 – 1.21 0.000374 1149 5877 exclusion phecode
507 Pleurisy; pleural effusion Respiratory 1.11 1.04 – 1.18 0.00225 1251 6279 exclusion phecode
508
Pulmonary collapse; interstitial and
Pulmonary collapse; interstitial and compensatory emphysema
 Respiratory 1.14 1.06 – 1.23 0.000347 943 5424 exclusion phecode
509 Respiratory failure, insufficiency, arrest Respiratory 1.14 1.08 – 1.21 8.21e-06 1656 7077 exclusion phecode
509.1 Respiratory failure Respiratory 1.18 1.09 – 1.28 5.26e-05 777 4461 exclusion phecode
509.2 Respiratory insufficiency Respiratory 1.19 1.07 – 1.31 0.000867 512 2695 exclusion phecode
509.3
Pulmonary insufficiency or respiratory failure
Pulmonary insufficiency or respiratory failure following trauma and surgery
 Respiratory 1.14 1.05 – 1.24 0.00121 784 3748 exclusion phecode
509.8
Dependence on respirator [Ventilator] or
Dependence on respirator [Ventilator] or supplemental oxygen
 Respiratory 1.19 1.09 – 1.29 0.000126 677 4112 exclusion phecode
510 Other diseases of lung Respiratory 1 0.956 – 1.05 0.874 2355 9188 exclusion phecode
510.2 Lung transplant Respiratory 1.28 1.03 – 1.6 0.027 109 400 exclusion phecode
512 Other symptoms of respiratory system Respiratory 1 0.963 – 1.04 0.941 8012 4835 exclusion phecode
512.1 Wheezing Respiratory 0.985 0.901 – 1.08 0.743 728 2444 exclusion phecode
512.2 Painful respiration Respiratory 0.983 0.916 – 1.06 0.645 1191 3813 exclusion phecode
512.3 Abnormal chest sounds Respiratory 1.01 0.832 – 1.22 0.945 166 472 exclusion phecode
512.7 Shortness of breath Respiratory 1.03 0.988 – 1.08 0.149 4495 4817 exclusion phecode
512.8 Cough Respiratory 0.994 0.951 – 1.04 0.77 4887 4834 exclusion phecode
512.9 Other dyspnea Respiratory 1.02 0.976 – 1.07 0.378 4718 4823 exclusion phecode
513 Respiratory abnormalities Respiratory 1.04 1 – 1.08 0.0424 5432 7412 exclusion phecode
513.3 Hypoventilation Respiratory 1.01 0.898 – 1.13 0.894 400 2016 exclusion phecode
513.31 Apnea Respiratory 0.999 0.857 – 1.17 0.993 233 1038 exclusion phecode
513.32 Orthopnea Respiratory 1 0.783 – 1.29 0.971 88 455 exclusion phecode
513.4 Hyperventilation Respiratory 1.02 0.88 – 1.18 0.784 241 1024 exclusion phecode
513.8 Disorders of diaphragm Respiratory 1.01 0.807 – 1.25 0.963 107 531 exclusion phecode
514 Abnormal findings examination of lungs Respiratory 1.02 0.964 – 1.07 0.536 1905 9092 exclusion phecode
514.1
Abnormal results of function study of pulmonary
Abnormal results of function study of pulmonary system
 Respiratory 1.25 1.03 – 1.53 0.0253 117 717 exclusion phecode
514.2 Solitary pulmonary nodule Respiratory 0.959 0.897 – 1.03 0.226 1098 7101 exclusion phecode
516 Abnormal sputum Respiratory 1.05 0.923 – 1.19 0.474 317 1985 exclusion phecode
516.1 Hemoptysis Respiratory 1.04 0.906 – 1.2 0.561 255 1654 exclusion phecode
519
Other diseases of respiratory system, not
Other diseases of respiratory system, not elsewhere classified
 Respiratory 1.1 1.05 – 1.16 3.31e-05 2619 9866 exclusion phecode
519.1 Tracheostomy complications Respiratory 1.13 0.832 – 1.53 0.441 47 485 exclusion phecode
519.2 Respiratory complications Respiratory 1.11 0.929 – 1.32 0.259 175 982 exclusion phecode
519.8 Other diseases of respiratory system, NEC Respiratory 1.07 0.983 – 1.17 0.114 629 4096 exclusion phecode
519.9
Symptoms involving respiratory system and other
Symptoms involving respiratory system and other chest symptoms
 Respiratory 1.12 1.06 – 1.18 4.03e-05 1944 8688 exclusion phecode
520 Disorders of tooth development Digestive 1.06 0.823 – 1.36 0.667 75 905 exclusion phecode
520.1 Hereditary disturbances in tooth structure Digestive 1.23 0.855 – 1.76 0.267 33 443 exclusion phecode
520.2 Disturbances in tooth eruption Digestive 0.865 0.613 – 1.22 0.406 39 483 exclusion phecode
521 Diseases of hard tissues of teeth Digestive 1.15 0.998 – 1.33 0.0529 222 2259 exclusion phecode
521.1 Dental caries Digestive 1.12 0.964 – 1.3 0.136 200 2133 exclusion phecode
521.2 Dental abrasion, erosion and attrition Digestive 1.09 0.675 – 1.76 0.727 19 129 exclusion phecode
522 Diseases of pulp and periapical tissues Digestive 1.05 0.883 – 1.24 0.602 172 1423 exclusion phecode
522.5 Periapical abscess Digestive 1.04 0.867 – 1.25 0.673 155 1201 exclusion phecode
523 Gingival and periodontal diseases Digestive 1.09 0.949 – 1.26 0.215 252 1873 exclusion phecode
523.1 Gingivitis Digestive 1.24 0.928 – 1.66 0.145 57 351 exclusion phecode
523.3 Periodontitis (acute or chronic) Digestive 0.858 0.703 – 1.05 0.133 132 949 exclusion phecode
523.31 Acute periodontitis Digestive 0.862 0.692 – 1.07 0.186 108 794 exclusion phecode
523.32 Chronic periodontitis Digestive 0.909 0.645 – 1.28 0.588 44 293 exclusion phecode
524 Dentofacial anomalies, including malocclusion Digestive 1.16 0.886 – 1.51 0.284 67 806 exclusion phecode
524.3 Anomalies of tooth position/malocclusion Digestive 1.03 0.721 – 1.47 0.879 42 444 exclusion phecode
525
Other diseases of the teeth and supporting
Other diseases of the teeth and supporting structures
 Digestive 1.03 0.914 – 1.17 0.605 321 2639 exclusion phecode
525.1 Loss of teeth or edentulism Digestive 0.976 0.783 – 1.22 0.829 91 945 exclusion phecode
526 Diseases of the jaws Digestive 0.957 0.888 – 1.03 0.249 895 6888 exclusion phecode
526.1 Cysts of the jaws Digestive 0.822 0.561 – 1.2 0.315 35 575 exclusion phecode
526.3 Anomalies of jaw size/symmetry Digestive 0.873 0.633 – 1.2 0.409 46 485 exclusion phecode
526.4 Temporomandibular joint disorders Digestive 0.964 0.879 – 1.06 0.437 590 3979 exclusion phecode
526.41 Temporomandibular joint disorder, unspecified Digestive 0.945 0.851 – 1.05 0.291 456 3146 exclusion phecode
526.42 Arthralgia/ankylosis of temporomandibular joint Digestive 0.982 0.852 – 1.13 0.799 242 1927 exclusion phecode
526.5 Inflammatory conditions of jaw Digestive 1.03 0.741 – 1.43 0.866 44 718 exclusion phecode
526.8 Exostosis of jaw Digestive 0.607 0.312 – 1.18 0.141 12 138 exclusion phecode
526.9 Jaw disease NOS Digestive 0.819 0.671 – 1 0.0512 118 1289 exclusion phecode
527 Diseases of the salivary glands Digestive 0.951 0.867 – 1.04 0.281 575 4647 exclusion phecode
527.1 Hypertrophy of salivary gland Digestive 1.4 0.816 – 2.39 0.224 15 160 exclusion phecode
527.2 Sialoadenitis Digestive 0.915 0.764 – 1.1 0.334 147 1064 exclusion phecode
527.7 Disturbance of salivary secretion Digestive 1 0.887 – 1.13 0.962 328 2503 exclusion phecode
527.8 Other specified diseases of the salivary glands Digestive 0.91 0.689 – 1.2 0.508 61 652 exclusion phecode
528
Diseases of the oral soft tissues, excluding
Diseases of the oral soft tissues, excluding lesions specific for gingiva and tongue
 Digestive 0.973 0.907 – 1.04 0.456 980 6986 exclusion phecode
528.1 Stomatitis and mucositis Digestive 0.901 0.788 – 1.03 0.127 280 1798 exclusion phecode
528.11 Stomatitis and mucositis (ulcerative) Digestive 0.908 0.716 – 1.15 0.425 85 537 exclusion phecode
528.12 Oral aphthae Digestive 0.835 0.679 – 1.03 0.0853 124 646 exclusion phecode
528.3 Cellulitis and abscess of oral soft tissues Digestive 1.17 0.906 – 1.51 0.228 74 573 exclusion phecode
528.4 Cysts of oral soft tissues Digestive 0.868 0.606 – 1.24 0.44 37 327 exclusion phecode
528.41 Cyst of the salivary gland Digestive 0.751 0.449 – 1.26 0.276 22 196 exclusion phecode
528.5 Diseases of lips Digestive 0.891 0.769 – 1.03 0.127 227 1300 exclusion phecode
528.6 Leukoplakia of oral mucosa Digestive 0.692 0.467 – 1.02 0.0657 28 332 exclusion phecode
528.7 Sialolithiasis Digestive 0.882 0.643 – 1.21 0.435 48 430 exclusion phecode
529 Diseases and other conditions of the tongue Digestive 0.965 0.839 – 1.11 0.621 253 1782 exclusion phecode
529.1 Glossitis Digestive 1.13 0.82 – 1.55 0.46 54 368 exclusion phecode
529.6 Glossodynia Digestive 0.864 0.643 – 1.16 0.329 57 471 exclusion phecode
530 Diseases of esophagus Digestive 1.01 0.969 – 1.05 0.714 5837 6541 exclusion phecode
530.1 Esophagitis, GERD and related diseases Digestive 1.01 0.971 – 1.05 0.641 5694 6541 exclusion phecode
530.11 GERD Digestive 1.01 0.971 – 1.05 0.621 5534 6540 exclusion phecode
530.12 Ulcer of esophagus Digestive 1.1 0.924 – 1.31 0.287 184 900 exclusion phecode
530.13 Barrett's esophagus Digestive 1.11 0.961 – 1.28 0.157 253 1745 exclusion phecode
530.14 Reflux esophagitis Digestive 0.996 0.925 – 1.07 0.92 968 4337 exclusion phecode
530.15 Eosinophilic esophagitis Digestive 1 0.801 – 1.26 0.973 109 541 exclusion phecode
530.2 Esophageal bleeding (varices/hemorrhage) Digestive 1.26 1.1 – 1.45 0.000964 279 1493 exclusion phecode
530.3 Stricture and stenosis of esophagus Digestive 0.997 0.883 – 1.13 0.964 354 2064 exclusion phecode
530.5 Disorders of esophageal motility Digestive 1.11 0.948 – 1.3 0.194 197 1315 exclusion phecode
530.6 Diverticulum of esophagus, acquired Digestive 1.37 0.85 – 2.22 0.196 19 274 exclusion phecode
530.7 Gastroesophageal laceration-hemorrhage syndrome Digestive 0.728 0.504 – 1.05 0.0905 38 233 exclusion phecode
530.9 Heartburn Digestive 1.11 1.01 – 1.2 0.0235 717 3738 exclusion phecode
531 Peptic ulcer (excl. esophageal) Digestive 0.989 0.917 – 1.07 0.772 871 5543 exclusion phecode
531.1 Hemorrhage from gastrointestinal ulcer Digestive 0.972 0.822 – 1.15 0.739 171 1005 exclusion phecode
531.2 Gastric ulcer Digestive 0.998 0.904 – 1.1 0.973 513 3213 exclusion phecode
531.3 Duodenal ulcer Digestive 1.01 0.857 – 1.18 0.944 211 1180 exclusion phecode
531.4 Peptic ulcer, site unspecified Digestive 0.989 0.881 – 1.11 0.852 365 2249 exclusion phecode
531.5 Gastrojejunal ulcer Digestive 1.17 0.906 – 1.51 0.228 67 381 exclusion phecode
532 Dysphagia Digestive 1.02 0.971 – 1.08 0.379 2027 6202 exclusion phecode
535 Gastritis and duodenitis Digestive 1.03 0.97 – 1.1 0.305 1249 6999 exclusion phecode
535.1 Acute gastritis Digestive 0.994 0.899 – 1.1 0.9 496 3012 exclusion phecode
535.2 Atrophic gastritis Digestive 0.982 0.817 – 1.18 0.851 155 851 exclusion phecode
535.6 Duodenitis Digestive 1.12 0.934 – 1.35 0.217 147 822 exclusion phecode
535.8 Other specified gastritis Digestive 1.05 0.92 – 1.2 0.462 297 1624 exclusion phecode
535.9 Gastritis and duodenitis, NOS Digestive 1.12 1.02 – 1.23 0.0143 602 3222 exclusion phecode
536 Disorders of function of stomach Digestive 1.03 0.968 – 1.09 0.36 1418 7106 exclusion phecode
536.3 Gastroparesis Digestive 0.987 0.865 – 1.13 0.842 283 1992 exclusion phecode
536.7
Complications of gastrostomy, colostomy and
Complications of gastrostomy, colostomy and enterostomy
 Digestive 1.28 1.06 – 1.53 0.00881 156 909 exclusion phecode
536.8
Dyspepsia and other specified disorders of
Dyspepsia and other specified disorders of function of stomach
 Digestive 1.03 0.961 – 1.1 0.411 1136 5538 exclusion phecode
537 Other disorders of stomach and duodenum Digestive 0.983 0.926 – 1.04 0.587 1424 7656 exclusion phecode
537.1 Lesions of stomach and duodenum Digestive 0.94 0.727 – 1.21 0.635 76 443 exclusion phecode
539 Bariatric surgery Digestive 1.03 0.941 – 1.12 0.567 692 4108 exclusion phecode
540 Appendiceal conditions Digestive 0.955 0.821 – 1.11 0.556 239 1344 exclusion phecode
540.1 Appendicitis Digestive 0.923 0.784 – 1.09 0.332 203 1129 exclusion phecode
540.11 Acute appendicitis Digestive 0.956 0.802 – 1.14 0.612 177 960 exclusion phecode
550 Abdominal hernia Digestive 1.03 0.988 – 1.08 0.152 2734 9494 exclusion phecode
550.1 Inguinal hernia Digestive 0.994 0.921 – 1.07 0.883 896 3825 exclusion phecode
550.2 Diaphragmatic hernia Digestive 1.05 0.979 – 1.12 0.183 1132 6653 exclusion phecode
550.3 Femoral hernia Digestive 1.07 0.812 – 1.4 0.643 78 331 exclusion phecode
550.4 Umbilical hernia Digestive 1.04 0.943 – 1.15 0.418 504 3157 exclusion phecode
550.5 Ventral hernia Digestive 1.06 0.982 – 1.15 0.135 807 5441 exclusion phecode
550.6 Incisional hernia Digestive 1.1 0.996 – 1.22 0.061 470 3249 exclusion phecode
555
Inflammatory bowel disease and other
Inflammatory bowel disease and other gastroenteritis and colitis
 Digestive 0.977 0.882 – 1.08 0.66 513 2900 exclusion phecode
555.1 Regional enteritis Digestive 1 0.877 – 1.15 0.954 295 1654 exclusion phecode
555.2 Ulcerative colitis Digestive 0.995 0.876 – 1.13 0.936 338 1782 exclusion phecode
555.21 Ulcerative colitis (chronic) Digestive 1.04 0.88 – 1.22 0.673 226 972 exclusion phecode
556 Ulceration of the lower GI tract Digestive 1.06 0.926 – 1.21 0.403 313 1248 exclusion phecode
556.1 Ulceration of intestine Digestive 1.04 0.904 – 1.21 0.553 272 1096 exclusion phecode
556.11
Angiodysplasia of intestine (without mention of
Angiodysplasia of intestine (without mention of hemorrhage)
 Digestive 0.876 0.692 – 1.11 0.269 117 427 exclusion phecode
557 Intestinal malabsorption (non-celiac) Digestive 0.975 0.901 – 1.05 0.525 902 3470 exclusion phecode
557.1 Celiac disease Digestive 1.04 0.883 – 1.23 0.618 197 936 exclusion phecode
558 Noninfectious gastroenteritis Digestive 1.01 0.953 – 1.08 0.648 1442 5180 exclusion phecode
559 Ileostomy status Digestive 1.12 0.986 – 1.28 0.0795 298 1588 exclusion phecode
560 Intestinal obstruction without mention of hernia Digestive 1.01 0.946 – 1.09 0.696 1166 4589 exclusion phecode
560.1 Paralytic ileus Digestive 0.978 0.889 – 1.07 0.64 615 2729 exclusion phecode
560.2 Impaction of intestine Digestive 1.21 1.02 – 1.44 0.0304 187 793 exclusion phecode
560.3 Peritoneal or intestinal adhesions Digestive 0.922 0.74 – 1.15 0.466 130 480 exclusion phecode
560.4 Other intestinal obstruction Digestive 1 0.916 – 1.1 0.943 679 2936 exclusion phecode
561 Symptoms involving digestive system Digestive 1.05 0.975 – 1.12 0.207 1148 4351 exclusion phecode
562 Diverticulosis and diverticulitis Digestive 0.96 0.911 – 1.01 0.123 3065 4544 exclusion phecode
562.1 Diverticulosis Digestive 0.96 0.911 – 1.01 0.125 3046 4529 exclusion phecode
562.2 Diverticulitis Digestive 0.959 0.873 – 1.05 0.384 607 2875 exclusion phecode
564 Functional digestive disorders Digestive 0.999 0.957 – 1.04 0.977 4483 5602 exclusion phecode
564.1 Irritable Bowel Syndrome Digestive 1.01 0.941 – 1.07 0.865 1319 4532 exclusion phecode
564.9 Personal history of diseases of digestive system Digestive 1.01 0.942 – 1.08 0.853 1275 4889 exclusion phecode
565 Anal and rectal conditions Digestive 1.01 0.95 – 1.07 0.837 1611 7075 exclusion phecode
565.1 Anal and rectal polyp Digestive 1 0.918 – 1.1 0.95 704 3054 exclusion phecode
567 Peritonitis and retroperitoneal infections Digestive 1.09 0.991 – 1.2 0.0768 567 2819 exclusion phecode
568 Other disorders of peritoneum Digestive 1.1 0.997 – 1.2 0.0575 564 3604 exclusion phecode
568.1
Peritoneal adhesions (postoperative)
Peritoneal adhesions (postoperative) (postinfection)
 Digestive 1.09 0.969 – 1.22 0.154 380 2646 exclusion phecode
569 Other disorders of intestine Digestive 1.02 0.976 – 1.06 0.398 3495 8030 exclusion phecode
569.1 Toxic gastroenteritis and colitis Digestive 1.23 0.993 – 1.52 0.0586 113 749 exclusion phecode
569.2 Gastrointestinal complications Digestive 1.05 0.961 – 1.16 0.264 589 3101 exclusion phecode
571 Chronic liver disease and cirrhosis Digestive 1.08 1.02 – 1.14 0.0125 1631 7612 exclusion phecode
571.5 Other chronic nonalcoholic liver disease Digestive 1.07 1.01 – 1.13 0.0288 1525 7555 exclusion phecode
571.51 Cirrhosis of liver without mention of alcohol Digestive 1.17 1.04 – 1.31 0.00778 390 2364 exclusion phecode
571.6 Primary biliary cirrhosis Digestive 1.13 0.882 – 1.46 0.325 85 411 exclusion phecode
571.8
Liver abscess and sequelae of chronic liver
Liver abscess and sequelae of chronic liver disease
 Digestive 1.2 1.07 – 1.35 0.00194 398 2213 exclusion phecode
571.81 Portal hypertension Digestive 1.12 0.974 – 1.29 0.11 257 1313 exclusion phecode
572 Ascites (non malignant) Digestive 1.05 0.978 – 1.13 0.169 915 5081 exclusion phecode
573 Other disorders of liver Digestive 1.06 1.01 – 1.12 0.0205 2124 7927 exclusion phecode
573.1 Chronic passive congestion of liver Digestive 1.21 0.926 – 1.57 0.164 81 300 exclusion phecode
573.2 Liver replaced by transplant Digestive 1.02 0.836 – 1.24 0.854 143 642 exclusion phecode
573.3 Hepatomegaly Digestive 1.14 0.944 – 1.37 0.177 142 1180 exclusion phecode
573.4 Acute and subacute necrosis of liver Digestive 1.15 0.948 – 1.39 0.156 153 721 exclusion phecode
573.5 Jaundice (not of newborn) Digestive 1.2 1.07 – 1.33 0.00117 438 2247 exclusion phecode
573.6
Nonspecific elevation of levels of transaminase
Nonspecific elevation of levels of transaminase or lactic acid dehydrogenase [LDH]
 Digestive 1.01 0.949 – 1.08 0.743 1291 6326 exclusion phecode
573.7 Abnormal results of function study of liver Digestive 1.02 0.962 – 1.08 0.484 1479 6669 exclusion phecode
573.9 Abnormal serum enzyme levels Digestive 1.02 0.967 – 1.07 0.514 2174 7977 exclusion phecode
574 Cholelithiasis and cholecystitis Digestive 1.03 0.968 – 1.09 0.367 1370 8140 exclusion phecode
574.1 Cholelithiasis Digestive 1.01 0.952 – 1.08 0.656 1271 7659 exclusion phecode
574.11 Cholelithiasis with acute cholecystitis Digestive 1.02 0.854 – 1.22 0.811 181 894 exclusion phecode
574.12 Cholelithiasis with other cholecystitis Digestive 0.895 0.778 – 1.03 0.124 252 1463 exclusion phecode
574.2 Calculus of bile duct Digestive 0.942 0.841 – 1.06 0.304 411 2203 exclusion phecode
574.3 Cholecystitis without cholelithiasis Digestive 1.06 0.942 – 1.19 0.329 384 2176 exclusion phecode
575 Other biliary tract disease Digestive 1.03 0.96 – 1.11 0.404 997 5862 exclusion phecode
575.1 Cholangitis Digestive 1.06 0.887 – 1.26 0.541 157 920 exclusion phecode
575.2 Obstruction of bile duct Digestive 1.15 1 – 1.33 0.0474 247 1575 exclusion phecode
575.6 Cholesterolosis of gallbladder Digestive 0.944 0.746 – 1.19 0.629 82 548 exclusion phecode
575.7 Other disorders of gallbladder Digestive 0.992 0.892 – 1.1 0.884 460 2478 exclusion phecode
575.8 Other disorders of biliary tract Digestive 1.11 1 – 1.23 0.0439 480 2888 exclusion phecode
575.9
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of biliary tract
 Digestive 1 0.812 – 1.24 0.974 116 674 exclusion phecode
577 Diseases of pancreas Digestive 1.1 1.02 – 1.18 0.0143 845 6200 exclusion phecode
577.1 Acute pancreatitis Digestive 1.11 1 – 1.23 0.0472 473 3347 exclusion phecode
577.2 Chronic pancreatitis Digestive 1.11 0.951 – 1.3 0.182 197 1346 exclusion phecode
577.3 Cyst and pseudocyst of pancreas Digestive 1.07 0.928 – 1.23 0.356 231 1591 exclusion phecode
578 Gastrointestinal hemorrhage Digestive 0.999 0.951 – 1.05 0.982 2208 8756 exclusion phecode
578.1 Hematemesis Digestive 1.08 0.934 – 1.26 0.286 243 1142 exclusion phecode
578.2 Blood in stool Digestive 1.01 0.951 – 1.08 0.71 1360 6398 exclusion phecode
578.8 Hemorrhage of rectum and anus Digestive 1 0.935 – 1.07 0.978 1142 5279 exclusion phecode
578.9 Hemorrhage of gastrointestinal tract Digestive 1.04 0.956 – 1.13 0.358 711 3612 exclusion phecode
579 Other symptoms involving abdomen and pelvis Digestive 1.09 1.04 – 1.15 0.00122 1854 8043 exclusion phecode
579.2 Splenomegaly Digestive 1.13 0.989 – 1.29 0.0724 301 1713 exclusion phecode
579.8 Nonspecific abnormal findings in stool contents Digestive 0.995 0.913 – 1.08 0.905 726 3475 exclusion phecode
580 Nephritis; nephrosis; renal sclerosis Genitourinary 1.05 0.965 – 1.14 0.265 767 3861 exclusion phecode
580.1 Glomerulonephritis Genitourinary 0.966 0.814 – 1.15 0.691 181 981 exclusion phecode
580.11 Proliferative glomerulonephritis Genitourinary 0.956 0.707 – 1.29 0.771 61 340 exclusion phecode
580.12 Non-proliferative glomerulonephritis Genitourinary 1.21 0.855 – 1.7 0.286 43 273 exclusion phecode
580.13 Acute glomerulonephritis, NOS Genitourinary 0.547 0.323 – 0.926 0.0246 25 146 exclusion phecode
580.14 Chronic glomerulonephritis, NOS Genitourinary 1.07 0.873 – 1.31 0.508 124 678 exclusion phecode
580.2
Nephrotic syndrome without mention of
Nephrotic syndrome without mention of glomerulonephritis
 Genitourinary 1.23 0.96 – 1.57 0.102 85 554 exclusion phecode
580.3
Nephritis and nephropathy without mention of
Nephritis and nephropathy without mention of glomerulonephritis
 Genitourinary 1.02 0.935 – 1.12 0.607 629 3062 exclusion phecode
580.31
Nephritis and nephropathy in diseases
Nephritis and nephropathy in diseases classified elsewhere
 Genitourinary 1.04 0.928 – 1.16 0.535 429 2061 exclusion phecode
580.32
Nephritis and nephropathy with pathological
Nephritis and nephropathy with pathological lesion
 Genitourinary 1.01 0.881 – 1.16 0.895 279 1728 exclusion phecode
580.4 Renal sclerosis, NOS Genitourinary 1.2 0.962 – 1.48 0.107 107 829 exclusion phecode
585 Renal failure Genitourinary 1.04 0.995 – 1.1 0.0781 2753 7867 exclusion phecode
585.1 Acute renal failure Genitourinary 1.06 1 – 1.13 0.0361 1748 6518 exclusion phecode
585.2 Renal failure NOS Genitourinary 0.965 0.852 – 1.09 0.577 348 2013 exclusion phecode
585.3 Chronic renal failure [CKD] Genitourinary 1.03 0.978 – 1.09 0.245 2026 7228 exclusion phecode
585.31 Renal dialysis Genitourinary 1.01 0.885 – 1.16 0.839 269 1824 exclusion phecode
585.32 End stage renal disease Genitourinary 1.05 0.934 – 1.17 0.443 414 2367 exclusion phecode
585.33 Chronic Kidney Disease, Stage III Genitourinary 1.01 0.941 – 1.07 0.873 1255 5199 exclusion phecode
585.34 Chronic Kidney Disease, Stage IV Genitourinary 0.989 0.881 – 1.11 0.851 389 2274 exclusion phecode
585.4 Chronic kidney disease, Stage I or II Genitourinary 1.05 0.951 – 1.15 0.347 546 2829 exclusion phecode
586 Other disorders of the kidney and ureters Genitourinary 1.04 0.992 – 1.09 0.108 2769 8213 exclusion phecode
586.1 Anatomical abnormatilies of kidney and ureters Genitourinary 1.33 1.08 – 1.64 0.00719 117 810 exclusion phecode
586.11 Small kidney Genitourinary 1.33 1.01 – 1.76 0.0408 64 530 exclusion phecode
586.12 Vesicoureteral reflux Genitourinary 1.13 0.811 – 1.56 0.477 49 317 exclusion phecode
586.2 Cyst of kidney, acquired Genitourinary 1.05 0.957 – 1.16 0.291 542 3031 exclusion phecode
586.3 Vascular disorders of kidney/hypertrophy Genitourinary 0.991 0.762 – 1.29 0.949 79 425 exclusion phecode
586.4 Stricture/obstruction of ureter Genitourinary 1.01 0.921 – 1.12 0.779 529 3830 exclusion phecode
587 Kidney replaced by transpant Genitourinary 1.02 0.904 – 1.15 0.756 390 1936 exclusion phecode
588 Disorders resulting from impaired renal function Genitourinary 0.99 0.884 – 1.11 0.864 440 2380 exclusion phecode
588.1 Renal osteodystrophy Genitourinary 1.12 0.908 – 1.39 0.287 136 638 exclusion phecode
588.2 Secondary hyperparathyroidism (of renal origin) Genitourinary 0.965 0.85 – 1.1 0.588 343 1886 exclusion phecode
589 Abnormal results of function study of kidney Genitourinary 1.01 0.906 – 1.13 0.855 452 2414 exclusion phecode
590 Pyelonephritis Genitourinary 1 0.913 – 1.1 0.973 606 3200 exclusion phecode
591 Urinary tract infection Genitourinary 1.03 0.986 – 1.07 0.196 4199 7295 exclusion phecode
592 Cystitis and urethritis Genitourinary 0.981 0.919 – 1.05 0.553 1301 5405 exclusion phecode
592.1 Cystitis Genitourinary 0.986 0.923 – 1.05 0.687 1242 5200 exclusion phecode
592.11 Acute cystitis Genitourinary 0.999 0.922 – 1.08 0.983 852 3738 exclusion phecode
592.12 Chronic cystitis Genitourinary 0.915 0.725 – 1.16 0.456 101 569 exclusion phecode
592.13 Chronic interstitial cystitis Genitourinary 1.16 0.955 – 1.41 0.134 133 937 exclusion phecode
592.2 Urethritis and urethral syndrome Genitourinary 0.864 0.666 – 1.12 0.268 83 477 exclusion phecode
593 Hematuria Genitourinary 1.01 0.962 – 1.07 0.602 2058 7184 exclusion phecode
593.1 Gross hematuria Genitourinary 0.983 0.896 – 1.08 0.712 604 3359 exclusion phecode
593.2 Microscopic hematuria Genitourinary 1.02 0.919 – 1.13 0.73 518 2368 exclusion phecode
594 Urinary calculus Genitourinary 1.04 0.99 – 1.1 0.112 2002 10238 exclusion phecode
594.1 Calculus of kidney Genitourinary 1.03 0.982 – 1.09 0.204 1886 10191 exclusion phecode
594.2 Calculus of lower urinary tract Genitourinary 1.03 0.838 – 1.27 0.775 113 1012 exclusion phecode
594.3 Calculus of ureter Genitourinary 1.05 0.953 – 1.16 0.321 528 3640 exclusion phecode
594.8 Renal colic Genitourinary 1.09 0.91 – 1.32 0.338 145 974 exclusion phecode
595 Hydronephrosis Genitourinary 1 0.91 – 1.1 0.969 525 4306 exclusion phecode
596 Other disorders of bladder Genitourinary 0.957 0.895 – 1.02 0.208 1079 7416 exclusion phecode
596.1 Bladder neck obstruction Genitourinary 0.853 0.7 – 1.04 0.116 125 1009 exclusion phecode
596.5 Functional disorders of bladder Genitourinary 0.935 0.857 – 1.02 0.134 639 4639 exclusion phecode
597 Other disorders of urethra and urinary tract Genitourinary 0.929 0.826 – 1.04 0.217 348 3089 exclusion phecode
597.1 Urethral stricture (not specified as infectious) Genitourinary 0.878 0.74 – 1.04 0.134 168 1610 exclusion phecode
597.2 Urinary complications NEC Genitourinary 0.987 0.871 – 1.12 0.835 313 2650 exclusion phecode
597.8 Urethral hypermobility/ISD Genitourinary 1.03 0.753 – 1.42 0.842 47 532 exclusion phecode
598 Abnormal findings on examination of urine Genitourinary 0.753 0.561 – 1.01 0.0599 52 378 exclusion phecode
598.4 Other cells and casts in urine Genitourinary 0.778 0.567 – 1.07 0.119 44 337 exclusion phecode
599 Other symptoms/disorders or the urinary system Genitourinary 1.01 0.967 – 1.04 0.8 5478 6851 exclusion phecode
599.1 Urinary obstruction Genitourinary 1.02 0.889 – 1.16 0.802 271 1479 exclusion phecode
599.2 Retention of urine Genitourinary 1.06 1 – 1.12 0.0491 1729 6078 exclusion phecode
599.3 Dysuria Genitourinary 0.999 0.947 – 1.05 0.969 2037 6219 exclusion phecode
599.4 Urinary incontinence Genitourinary 0.963 0.911 – 1.02 0.178 2002 6018 exclusion phecode
599.5 Frequency of urination and polyuria Genitourinary 1.02 0.967 – 1.07 0.52 2384 6528 exclusion phecode
599.6 Oliguria and anuria Genitourinary 1.05 0.917 – 1.21 0.469 283 1237 exclusion phecode
599.7 Urethral discharge Genitourinary 0.968 0.725 – 1.29 0.826 58 304 exclusion phecode
599.8 Other symptoms involving urinary system Genitourinary 1.01 0.96 – 1.07 0.613 2008 6261 exclusion phecode
599.9 Other abnormality of urination Genitourinary 0.985 0.924 – 1.05 0.649 1315 5670 exclusion phecode
600 Hyperplasia of prostate Genitourinary 1.02 0.95 – 1.1 0.583 1625 2624 exclusion phecode
601 Inflammatory diseases of prostate Genitourinary 1.09 0.976 – 1.21 0.129 446 2297 exclusion phecode
601.1 Prostatitis Genitourinary 1.02 0.884 – 1.19 0.745 225 1102 exclusion phecode
601.11 Acute prostatitis Genitourinary 0.802 0.587 – 1.1 0.168 51 277 exclusion phecode
601.12 Chronic prostatitis Genitourinary 0.969 0.69 – 1.36 0.855 46 241 exclusion phecode
601.3 Orchitis and epididymitis Genitourinary 1.21 1.01 – 1.46 0.0354 158 872 exclusion phecode
601.4 Balanoposthitis Genitourinary 0.992 0.717 – 1.37 0.962 47 285 exclusion phecode
601.8
Other inflammatory disorders of male genital
Other inflammatory disorders of male genital organs
 Genitourinary 1.1 0.815 – 1.48 0.54 60 380 exclusion phecode
602 Other disorders of prostate Genitourinary 0.998 0.826 – 1.21 0.985 147 788 exclusion phecode
602.3 Dysplasia of prostate Genitourinary 1.11 0.739 – 1.67 0.61 31 181 exclusion phecode
603 Other disorders of testis Genitourinary 0.894 0.745 – 1.07 0.23 168 905 exclusion phecode
603.1 Hydrocele Genitourinary 0.916 0.735 – 1.14 0.436 116 596 exclusion phecode
603.2 Spermatocele Genitourinary 0.923 0.695 – 1.23 0.582 69 325 exclusion phecode
604 Disorders of penis Genitourinary 1.04 0.894 – 1.21 0.61 221 1293 exclusion phecode
604.1 Redundant prepuce and phimosis/BXO Genitourinary 1.04 0.759 – 1.42 0.809 52 306 exclusion phecode
604.3 Peyronie's disease Genitourinary 1.28 0.957 – 1.72 0.0959 60 405 exclusion phecode
605 Erectile dysfunction [ED] Genitourinary 1.03 0.954 – 1.1 0.484 1392 2552 exclusion phecode
608 Other disorders of male genital organs Genitourinary 0.995 0.909 – 1.09 0.904 694 2692 exclusion phecode
609 Male infertility and abnormal spermatozoa Genitourinary 0.848 0.711 – 1.01 0.0676 181 990 exclusion phecode
609.1 Infertility, male Genitourinary 0.862 0.698 – 1.06 0.169 117 676 exclusion phecode
609.11 Azoospermia and oligospermia Genitourinary 0.577 0.362 – 0.922 0.0213 25 208 exclusion phecode
609.2 Abnormal spermatozoa Genitourinary 0.859 0.652 – 1.13 0.278 75 342 exclusion phecode
610 Benign mammary dysplasias Genitourinary 0.907 0.85 – 0.967 0.00295 1697 3238 exclusion phecode
610.1 Cystic mastopathy Genitourinary 0.873 0.801 – 0.952 0.00213 746 2745 exclusion phecode
610.2 Fibroadenosis of breast Genitourinary 1.16 0.778 – 1.73 0.465 33 113 exclusion phecode
610.4 Benign neoplasm of breast Genitourinary 0.919 0.857 – 0.986 0.0188 1324 3195 exclusion phecode
610.8 Other specified benign mammary dysplasias Genitourinary 0.877 0.793 – 0.97 0.011 521 2334 exclusion phecode
611 Abnormal findings on mammogram or breast exam Genitourinary 0.934 0.886 – 0.984 0.0102 3231 3904 exclusion phecode
611.1 Abnormal mammogram Genitourinary 0.916 0.866 – 0.97 0.00242 2700 3217 exclusion phecode
611.11 Mammographic microcalcification Genitourinary 0.92 0.838 – 1.01 0.078 667 2028 exclusion phecode
611.3 Lump or mass in breast Genitourinary 0.919 0.866 – 0.976 0.00577 1893 3866 exclusion phecode
612
Breast conditions, congenital or relating to
Breast conditions, congenital or relating to hormones
 Genitourinary 0.886 0.795 – 0.989 0.0305 450 2195 exclusion phecode
612.1 Galactorrhea Genitourinary 0.731 0.55 – 0.971 0.0308 71 306 exclusion phecode
612.2 Hypertrophy of breast (Gynecomastia) Genitourinary 0.964 0.849 – 1.1 0.575 330 1663 exclusion phecode
612.3 Congenital anomalies of breast Genitourinary 0.984 0.67 – 1.45 0.935 40 173 exclusion phecode
613 Other nonmalignant breast conditions Genitourinary 0.983 0.93 – 1.04 0.557 1886 5695 exclusion phecode
613.1 Inflammatory disease of breast Genitourinary 1.02 0.886 – 1.17 0.797 260 1574 exclusion phecode
613.5 Mastodynia Genitourinary 1 0.927 – 1.08 0.965 892 4281 exclusion phecode
613.7 Other signs and symptoms in breast Genitourinary 1.02 0.917 – 1.13 0.736 476 2388 exclusion phecode
613.8 Other specified disorders of breast Genitourinary 0.913 0.818 – 1.02 0.108 430 2379 exclusion phecode
613.9 Breast disorder NOS Genitourinary 1.02 0.932 – 1.11 0.685 660 3644 exclusion phecode
614 Inflammatory diseases of female pelvic organs Genitourinary 0.992 0.937 – 1.05 0.785 1893 4915 exclusion phecode
614.1
Pelvic peritoneal adhesions, female
Pelvic peritoneal adhesions, female (postoperative) (postinfection)
 Genitourinary 0.97 0.783 – 1.2 0.785 109 784 exclusion phecode
614.3 Pelvic inflammatory disease (PID) Genitourinary 0.993 0.849 – 1.16 0.927 202 1117 exclusion phecode
614.31 Acute inflammatory pelvic disease Genitourinary 1.16 0.803 – 1.68 0.426 38 212 exclusion phecode
614.32 Chronic inflammatory pelvic disease Genitourinary 1.04 0.796 – 1.36 0.768 75 404 exclusion phecode
614.33 Pelvic inflammatory disease, NOS Genitourinary 0.91 0.734 – 1.13 0.393 111 585 exclusion phecode
614.4 Inflammatory diseases of uterus, except cervix Genitourinary 1.02 0.789 – 1.32 0.874 83 397 exclusion phecode
614.5
Inflammatory disease of cervix, vagina, and
Inflammatory disease of cervix, vagina, and vulva
 Genitourinary 0.983 0.927 – 1.04 0.573 1708 4878 exclusion phecode
614.51 Cervicitis and endocervicitis Genitourinary 0.854 0.694 – 1.05 0.137 134 663 exclusion phecode
614.52 Vaginitis and vulvovaginitis Genitourinary 0.985 0.925 – 1.05 0.628 1494 4734 exclusion phecode
614.53 Cyst or abscess of Bartholin's gland Genitourinary 0.83 0.627 – 1.1 0.193 74 371 exclusion phecode
614.54 Abscess or ulceration of vulva Genitourinary 0.821 0.66 – 1.02 0.075 102 576 exclusion phecode
615 Endometriosis Genitourinary 1.06 0.963 – 1.16 0.243 559 3571 exclusion phecode
618 Genital prolapse Genitourinary 0.947 0.872 – 1.03 0.2 729 5155 exclusion phecode
618.1 Prolapse of vaginal walls Genitourinary 0.925 0.836 – 1.02 0.133 470 3849 exclusion phecode
618.2 Uterine/Uterovaginal prolapse Genitourinary 1.05 0.901 – 1.22 0.529 212 1524 exclusion phecode
618.5 Prolapse of vaginal vault after hysterectomy Genitourinary 1 0.767 – 1.31 0.981 62 867 exclusion phecode
618.6 Vaginal enterocele, congenital or acquired Genitourinary 1.07 0.894 – 1.29 0.449 137 1246 exclusion phecode
619 Noninflammatory female genital disorders Genitourinary 0.986 0.936 – 1.04 0.59 2563 4558 exclusion phecode
619.1
Noninflammatory disorders of ovary, fallopian
Noninflammatory disorders of ovary, fallopian tube, and broad ligament
 Genitourinary 0.996 0.901 – 1.1 0.934 505 2801 exclusion phecode
619.2 Disorders of uterus, NEC Genitourinary 1.02 0.889 – 1.16 0.821 293 1443 exclusion phecode
619.3 Noninflammatory disorders of cervix Genitourinary 1.07 0.926 – 1.24 0.35 246 1134 exclusion phecode
619.4 Noninflammatory disorders of vagina Genitourinary 0.983 0.918 – 1.05 0.621 1203 4452 exclusion phecode
619.5 Noninflammatory disorders of vulva and perineum Genitourinary 0.96 0.874 – 1.05 0.393 583 2989 exclusion phecode
620 Dysplasia of female genital organs Genitourinary 0.951 0.796 – 1.13 0.575 164 1024 exclusion phecode
620.1 Dysplasia of cervix Genitourinary 0.913 0.723 – 1.15 0.445 91 461 exclusion phecode
621 Endometrial hyperplasia Genitourinary 0.91 0.774 – 1.07 0.255 188 1123 exclusion phecode
622 Polyp of female genital organs Genitourinary 0.931 0.859 – 1.01 0.0788 833 3894 exclusion phecode
622.1 Polyp of corpus uteri Genitourinary 0.965 0.88 – 1.06 0.445 638 3034 exclusion phecode
622.2 Mucous polyp of cervix Genitourinary 0.867 0.757 – 0.993 0.0393 290 1215 exclusion phecode
623 Hypertrophy of female genital organs Genitourinary 0.961 0.857 – 1.08 0.494 401 2257 exclusion phecode
624 Symptoms involving female genital tract Genitourinary 1.01 0.925 – 1.11 0.795 689 2702 exclusion phecode
624.1 Dystrophy of female genital tract Genitourinary 0.959 0.748 – 1.23 0.743 92 474 exclusion phecode
624.2 Atrophy of female genital tract Genitourinary 1.35 0.877 – 2.08 0.173 35 142 exclusion phecode
624.9 stress incontinence, female Genitourinary 0.953 0.878 – 1.03 0.253 808 3379 exclusion phecode
625
Pain and other symptoms associated with female
Pain and other symptoms associated with female genital organs
 Genitourinary 0.996 0.945 – 1.05 0.88 2782 3788 exclusion phecode
625.1 Dyspareunia Genitourinary 0.957 0.866 – 1.06 0.393 551 2620 exclusion phecode
626
Disorders of menstruation and other abnormal
Disorders of menstruation and other abnormal bleeding from female genital tract
 Genitourinary 0.982 0.927 – 1.04 0.527 2916 2905 exclusion phecode
626.1 Irregular menstrual cycle/bleeding Genitourinary 0.991 0.931 – 1.05 0.767 2359 2682 exclusion phecode
626.11 Absent or infrequent menstruation Genitourinary 0.999 0.901 – 1.11 0.991 572 1532 exclusion phecode
626.12 Excessive or frequent menstruation Genitourinary 1.01 0.933 – 1.09 0.864 1212 2160 exclusion phecode
626.13 Irregular menstrual cycle Genitourinary 0.965 0.893 – 1.04 0.372 1135 2254 exclusion phecode
626.14 Irregular menstrual bleeding Genitourinary 0.981 0.884 – 1.09 0.725 559 1615 exclusion phecode
626.15 Infertility, female, associated with anovulation Genitourinary 0.949 0.809 – 1.11 0.516 237 783 exclusion phecode
626.2 Dysmenorrhea Genitourinary 1.01 0.92 – 1.12 0.774 659 1749 exclusion phecode
626.4 Premenstrual tension syndromes Genitourinary 1.08 0.906 – 1.29 0.385 198 646 exclusion phecode
626.8 Infertility, female Genitourinary 1 0.889 – 1.13 0.989 432 1241 exclusion phecode
627 Menopausal and postmenopausal disorders Genitourinary 0.968 0.912 – 1.03 0.272 2393 2720 exclusion phecode
627.1 Postmenopausal bleeding Genitourinary 0.981 0.893 – 1.08 0.685 633 1976 exclusion phecode
627.2 Symptomatic menopause Genitourinary 0.941 0.88 – 1.01 0.0739 1649 2562 exclusion phecode
627.21 Symptomatic artificial menopause Genitourinary 0.917 0.69 – 1.22 0.553 70 304 exclusion phecode
627.22
Need for Hormone replacement therapy
Need for Hormone replacement therapy (postmenopausal)
 Genitourinary 0.912 0.776 – 1.07 0.263 220 737 exclusion phecode
627.3 Postmenopausal atrophic vaginitis Genitourinary 1.03 0.933 – 1.15 0.519 531 1842 exclusion phecode
627.4 Premenopausal menorrhagia Genitourinary 0.978 0.826 – 1.16 0.798 215 685 exclusion phecode
627.5 Premature menopause and other ovarian failure Genitourinary 0.927 0.763 – 1.13 0.441 154 593 exclusion phecode
628 Ovarian cyst Genitourinary 0.971 0.896 – 1.05 0.469 940 2535 exclusion phecode
634 Miscarriage; stillbirth Pregnancy Complications 1.01 0.904 – 1.13 0.862 427 2151 exclusion phecode
634.1 Missed abortion/Hydatidiform mole Pregnancy Complications 0.876 0.728 – 1.05 0.16 156 775 exclusion phecode
634.3 Ectopic pregnancy Pregnancy Complications 1.15 0.844 – 1.56 0.379 57 320 exclusion phecode
635
Hemorrhage during pregnancy; childbirth and
Hemorrhage during pregnancy; childbirth and postpartum
 Pregnancy Complications 0.954 0.833 – 1.09 0.498 287 1381 exclusion phecode
635.2
Antepartum hemorrhage, abruptio placentae, and
Antepartum hemorrhage, abruptio placentae, and placenta previa
 Pregnancy Complications 0.902 0.763 – 1.07 0.229 196 959 exclusion phecode
635.3 Placenta previa and abruptio placenta Pregnancy Complications 0.992 0.816 – 1.21 0.934 141 735 exclusion phecode
636
Early or threatened labor; hemorrhage in early
Early or threatened labor; hemorrhage in early pregnancy
 Pregnancy Complications 0.995 0.9 – 1.1 0.915 584 2070 exclusion phecode
636.1 Threatened premature labor Pregnancy Complications 1.04 0.881 – 1.23 0.638 198 925 exclusion phecode
636.2 Early onset of delivery Pregnancy Complications 0.975 0.808 – 1.18 0.795 163 741 exclusion phecode
636.3 Hemorrhage in early pregnancy Pregnancy Complications 1.04 0.898 – 1.2 0.607 252 1121 exclusion phecode
636.8 Cervical incompetence Pregnancy Complications 1.51 1.03 – 2.2 0.0338 38 199 exclusion phecode
637
Short gestation; low birth weight; and fetal
Short gestation; low birth weight; and fetal growth retardation
 Pregnancy Complications 1.11 0.767 – 1.62 0.57 35 190 exclusion phecode
642
Hypertension complicating pregnancy
Hypertension complicating pregnancy, childbirth, and the puerperium
 Pregnancy Complications 0.923 0.805 – 1.06 0.249 282 1712 exclusion phecode
642.1 Preeclampsia and eclampsia Pregnancy Complications 0.842 0.7 – 1.01 0.0663 151 931 exclusion phecode
643 Excessive vomiting in pregnancy Pregnancy Complications 0.933 0.767 – 1.13 0.489 139 743 exclusion phecode
643.1 Hyperemesis gravidarum Pregnancy Complications 0.863 0.661 – 1.13 0.277 75 357 exclusion phecode
644 Anemia during pregnancy Pregnancy Complications 1.01 0.821 – 1.25 0.903 116 644 exclusion phecode
646 Other complications of pregnancy NEC Pregnancy Complications 1.02 0.903 – 1.14 0.789 402 1729 exclusion phecode
647
Infectious and parasitic complications
Infectious and parasitic complications affecting pregnancy
 Pregnancy Complications 0.923 0.744 – 1.15 0.467 116 666 exclusion phecode
647.1
Infections of genitourinary tract during
Infections of genitourinary tract during pregnancy
 Pregnancy Complications 1.25 0.991 – 1.59 0.0599 101 598 exclusion phecode
647.3 Major puerperal infection Pregnancy Complications 1.13 0.75 – 1.71 0.557 34 196 exclusion phecode
649
Other conditions or status of the mother
Other conditions or status of the mother complicating pregnancy, childbirth, or the puerperium
 Pregnancy Complications 0.921 0.837 – 1.01 0.0892 649 2106 exclusion phecode
649.1
Diabetes or abnormal glucose tolerance
Diabetes or abnormal glucose tolerance complicating pregnancy
 Pregnancy Complications 0.992 0.87 – 1.13 0.905 332 1683 exclusion phecode
653
Problems associated with amniotic cavity and
Problems associated with amniotic cavity and membranes
 Pregnancy Complications 0.947 0.831 – 1.08 0.413 311 1494 exclusion phecode
654.1
Abnormality of organs and soft tissues of
Abnormality of organs and soft tissues of pelvis complicating pregnancy, childbirth, or the puerperium
 Pregnancy Complications 0.941 0.758 – 1.17 0.581 111 550 exclusion phecode
654.2 Rhesus isoimmunization in pregnancy Pregnancy Complications 0.819 0.66 – 1.02 0.0716 116 538 exclusion phecode
655
Known or suspected fetal abnormality affecting
Known or suspected fetal abnormality affecting management of mother
 Pregnancy Complications 0.962 0.885 – 1.04 0.352 870 2682 exclusion phecode
655.1 Abnormality in fetal heart rate or rhythm Pregnancy Complications 1.06 0.929 – 1.2 0.406 340 1395 exclusion phecode
656 Other perinatal conditions of fetus or newborn Pregnancy Complications 1.03 0.919 – 1.15 0.614 428 1826 exclusion phecode
656.2 Respiratory conditions of fetus and newborn Pregnancy Complications 0.812 0.561 – 1.17 0.268 34 192 exclusion phecode
669 Complications of labor and delivery NEC Pregnancy Complications 1.01 0.907 – 1.14 0.799 423 1862 exclusion phecode
671
Venous/cerebrovascular complications embolism
Venous/cerebrovascular complications embolism in pregnancy and the puerperium
 Pregnancy Complications 0.988 0.777 – 1.26 0.924 92 642 exclusion phecode
674 Other complications of the puerperium NEC Pregnancy Complications 0.905 0.692 – 1.18 0.464 71 462 exclusion phecode
676
Other disorders of the breast associated with
Other disorders of the breast associated with childbirth and disorders of lactation
 Pregnancy Complications 1.01 0.814 – 1.27 0.895 105 558 exclusion phecode
681 Superficial cellulitis and abscess Dermatologic 0.983 0.94 – 1.03 0.463 2831 9221 exclusion phecode
681.1 Cellulitis and abscess of fingers/toes Dermatologic 0.991 0.905 – 1.09 0.849 636 3214 exclusion phecode
681.2 Cellulitis and abscess of face/neck Dermatologic 1.05 0.94 – 1.17 0.387 418 2480 exclusion phecode
681.3 Cellulitis and abscess of arm/hand Dermatologic 0.972 0.904 – 1.05 0.447 977 4976 exclusion phecode
681.5 Cellulitis and abscess of leg, except foot Dermatologic 0.956 0.89 – 1.03 0.215 1017 5206 exclusion phecode
681.6 Cellulitis and abscess of foot, toe Dermatologic 0.965 0.891 – 1.05 0.386 807 4224 exclusion phecode
681.7 Cellulitis and abscess of trunk Dermatologic 1.02 0.93 – 1.11 0.696 616 3886 exclusion phecode
686
Other local infections of skin and subcutaneous
Other local infections of skin and subcutaneous tissue
 Dermatologic 1 0.932 – 1.08 0.936 945 5396 exclusion phecode
686.1 Carbuncle and furuncle Dermatologic 0.897 0.779 – 1.03 0.134 262 1483 exclusion phecode
686.2 Impetigo Dermatologic 1.01 0.862 – 1.19 0.87 215 1087 exclusion phecode
686.3 Pilonidal cyst Dermatologic 0.879 0.669 – 1.16 0.358 69 451 exclusion phecode
686.4 Pyogenic granuloma Dermatologic 1.2 0.912 – 1.57 0.195 68 401 exclusion phecode
686.5 Pyoderma Dermatologic 0.785 0.497 – 1.24 0.298 29 166 exclusion phecode
687 Symptoms affecting skin Dermatologic 0.947 0.874 – 1.03 0.177 849 3745 exclusion phecode
687.1 Rash and other nonspecific skin eruption Dermatologic 0.975 0.935 – 1.02 0.255 3608 7324 exclusion phecode
687.3 Changes in skin texture Dermatologic 1.03 0.878 – 1.21 0.716 192 1080 exclusion phecode
687.4 Disturbance of skin sensation Dermatologic 0.965 0.921 – 1.01 0.144 2719 7263 exclusion phecode
689 Disorder of skin and subcutaneous tissue NOS Dermatologic 1.03 0.993 – 1.07 0.112 4627 8202 exclusion phecode
690 Erythematosquamous dermatosis Dermatologic 0.993 0.947 – 1.04 0.767 2865 7182 exclusion phecode
690.1 Seborrheic dermatitis Dermatologic 0.993 0.948 – 1.04 0.786 2859 7172 exclusion phecode
691 Congenital anomalies of skin Dermatologic 0.895 0.777 – 1.03 0.125 252 1243 exclusion phecode
691.3 Congenital pigmentary anomalies of skin Dermatologic 1.01 0.607 – 1.67 0.983 20 136 exclusion phecode
694 Dyschromia and Vitiligo Dermatologic 0.973 0.905 – 1.05 0.463 1036 4202 exclusion phecode
694.1 Vitiligo Dermatologic 0.856 0.653 – 1.12 0.258 69 348 exclusion phecode
694.2 Other dyschromia Dermatologic 0.976 0.905 – 1.05 0.519 952 3790 exclusion phecode
694.3 Vascular disorders of skin Dermatologic 1.48 0.996 – 2.2 0.0523 38 187 exclusion phecode
695 Erythematous conditions Dermatologic 0.954 0.904 – 1.01 0.0892 1948 6851 exclusion phecode
695.1 Toxic erythema Dermatologic 0.737 0.497 – 1.1 0.131 27 181 exclusion phecode
695.2 Bullous dermatoses Dermatologic 1.39 0.953 – 2.02 0.0876 32 202 exclusion phecode
695.3 Rosacea Dermatologic 0.909 0.846 – 0.977 0.00991 1012 4149 exclusion phecode
695.4 Lupus (localized and systemic) Dermatologic 1.02 0.884 – 1.17 0.796 253 1491 exclusion phecode
695.41 Cutaneous lupus erythematosus Dermatologic 0.967 0.774 – 1.21 0.771 105 555 exclusion phecode
695.42 Systemic lupus erythematosus Dermatologic 1.01 0.878 – 1.17 0.851 243 1408 exclusion phecode
695.7 Prurigo and Lichen Dermatologic 1.07 0.936 – 1.22 0.326 277 1396 exclusion phecode
695.8 Other specified erythematous conditions Dermatologic 0.909 0.81 – 1.02 0.105 400 1870 exclusion phecode
695.81 Erythema nodosum Dermatologic 0.682 0.419 – 1.11 0.122 31 118 exclusion phecode
695.9 Unspecified erythematous condition Dermatologic 0.945 0.824 – 1.08 0.416 282 1537 exclusion phecode
696 Psoriasis and related disorders Dermatologic 0.999 0.91 – 1.1 0.983 574 3119 exclusion phecode
696.3 Pityriasis Dermatologic 1.05 0.748 – 1.48 0.768 52 198 exclusion phecode
696.4 Psoriasis Dermatologic 1.02 0.922 – 1.12 0.739 520 2917 exclusion phecode
696.41 Psoriasis vulgaris Dermatologic 1.02 0.919 – 1.12 0.756 495 2697 exclusion phecode
696.42 Psoriatic arthropathy Dermatologic 0.916 0.732 – 1.14 0.438 94 602 exclusion phecode
697 Sarcoidosis Dermatologic 1.04 0.856 – 1.27 0.671 126 757 exclusion phecode
698 Pruritus and related conditions Dermatologic 0.988 0.924 – 1.06 0.724 1142 6186 exclusion phecode
700 Corns and callosities Dermatologic 1.05 0.97 – 1.15 0.213 762 2941 exclusion phecode
701
Other hypertrophic and atrophic conditions of
Other hypertrophic and atrophic conditions of skin
 Dermatologic 0.989 0.949 – 1.03 0.617 3478 8870 exclusion phecode
701.1 Keratoderma, acquired Dermatologic 1.06 0.928 – 1.21 0.402 299 1424 exclusion phecode
701.2 Scar conditions and fibrosis of skin Dermatologic 0.926 0.854 – 1 0.0633 769 4953 exclusion phecode
701.3 Circumscribed scleroderma Dermatologic 0.989 0.857 – 1.14 0.879 247 1411 exclusion phecode
701.4 Keloid scar Dermatologic 0.945 0.815 – 1.09 0.447 240 1370 exclusion phecode
701.5 Abnormal granulation tissue Dermatologic 1.02 0.849 – 1.22 0.845 135 899 exclusion phecode
702
Degenerative skin conditions and other
Degenerative skin conditions and other dermatoses
 Dermatologic 0.987 0.944 – 1.03 0.559 3793 6225 exclusion phecode
702.1 Actinic keratosis Dermatologic 0.977 0.928 – 1.03 0.388 2360 5883 exclusion phecode
702.2 Seborrheic keratosis Dermatologic 0.989 0.945 – 1.04 0.64 3074 7285 exclusion phecode
702.4 Degenerative skin disorders Dermatologic 0.99 0.706 – 1.39 0.955 44 232 exclusion phecode
703 Diseases of nail, NOS Dermatologic 0.92 0.852 – 0.994 0.0338 896 4080 exclusion phecode
703.1 Ingrowing nail Dermatologic 0.928 0.836 – 1.03 0.164 481 2496 exclusion phecode
704 Diseases of hair and hair follicles Dermatologic 1.01 0.953 – 1.07 0.764 1619 7657 exclusion phecode
704.1 Alopecia Dermatologic 1 0.919 – 1.09 0.994 734 3660 exclusion phecode
704.11 Alopecia Areata Dermatologic 1.12 0.805 – 1.56 0.504 50 202 exclusion phecode
704.12 Telogen effluvium Dermatologic 0.966 0.646 – 1.45 0.867 40 135 exclusion phecode
704.2 Hirsutism Dermatologic 0.993 0.819 – 1.2 0.941 147 767 exclusion phecode
704.8
Other specified diseases of hair and hair
Other specified diseases of hair and hair follicles
 Dermatologic 0.993 0.921 – 1.07 0.851 918 4633 exclusion phecode
705 Disorders of sweat glands Dermatologic 0.97 0.846 – 1.11 0.667 266 1484 exclusion phecode
705.1 Dyshidrosis Dermatologic 0.864 0.671 – 1.11 0.257 90 392 exclusion phecode
705.3 Hidradenitis Dermatologic 1.02 0.8 – 1.31 0.845 76 561 exclusion phecode
705.8 Hyperhidrosis Dermatologic 1.08 0.982 – 1.19 0.109 560 2681 exclusion phecode
706 Diseases of sebaceous glands Dermatologic 1 0.961 – 1.05 0.895 3255 9128 exclusion phecode
706.1 Acne Dermatologic 1.01 0.95 – 1.08 0.738 1449 5362 exclusion phecode
706.2 Sebaceous cyst Dermatologic 1.02 0.962 – 1.08 0.508 1553 6576 exclusion phecode
706.3 Seborrhea Dermatologic 1.14 0.723 – 1.8 0.57 30 140 exclusion phecode
706.8 Other specified diseases of sebaceous glands Dermatologic 0.957 0.887 – 1.03 0.257 925 3947 exclusion phecode
707 Chronic ulcer of skin Dermatologic 1.05 0.983 – 1.12 0.145 1118 7230 exclusion phecode
707.1 Decubitus ulcer Dermatologic 1.12 0.994 – 1.26 0.0617 351 2150 exclusion phecode
707.2 Chronic ulcer of leg or foot Dermatologic 0.995 0.896 – 1.1 0.92 462 2833 exclusion phecode
707.3 Chronic ulcer of unspecified site Dermatologic 1.01 0.927 – 1.1 0.786 627 4477 exclusion phecode
709 Diffuse diseases of connective tissue Dermatologic 0.943 0.862 – 1.03 0.199 643 3346 exclusion phecode
709.2 Sicca syndrome Dermatologic 0.944 0.809 – 1.1 0.467 217 1099 exclusion phecode
709.3 Systemic sclerosis Dermatologic 1.01 0.775 – 1.3 0.97 74 477 exclusion phecode
709.5 Dermatomyositis Dermatologic 0.867 0.598 – 1.26 0.45 37 217 exclusion phecode
709.6
Other specified diffuse diseases of connective
Other specified diffuse diseases of connective tissue
 Dermatologic 1.03 0.707 – 1.49 0.887 38 187 exclusion phecode
709.7 Unspecified diffuse connective tissue disease Dermatologic 0.935 0.837 – 1.04 0.237 431 2163 exclusion phecode
710
Osteomyelitis, periostitis, and other
Osteomyelitis, periostitis, and other infections involving bone
 Musculoskeletal 0.968 0.864 – 1.08 0.575 384 2840 exclusion phecode
710.1 Osteomyelitis Musculoskeletal 0.974 0.867 – 1.09 0.652 367 2745 exclusion phecode
710.11 Acute osteomyelitis Musculoskeletal 0.971 0.825 – 1.14 0.725 180 1425 exclusion phecode
710.12 Chronic osteomyelitis Musculoskeletal 0.924 0.776 – 1.1 0.37 167 1256 exclusion phecode
710.19 Unspecified osteomyelitis Musculoskeletal 0.973 0.864 – 1.1 0.658 348 2615 exclusion phecode
711 Arthropathy associated with infections Musculoskeletal 0.96 0.798 – 1.15 0.661 151 878 exclusion phecode
711.1 Pyogenic arthritis Musculoskeletal 0.936 0.74 – 1.18 0.581 100 618 exclusion phecode
712 Infective connective tissue disorders Musculoskeletal 0.859 0.661 – 1.12 0.257 75 407 exclusion phecode
713
Arthropathy associated with other disorders
Arthropathy associated with other disorders classified elsewhere
 Musculoskeletal 0.909 0.747 – 1.11 0.34 117 912 exclusion phecode
713.5
Arthropathy associated with neurological
Arthropathy associated with neurological disorders
 Musculoskeletal 0.893 0.695 – 1.15 0.379 74 591 exclusion phecode
714
Rheumatoid arthritis and other inflammatory
Rheumatoid arthritis and other inflammatory polyarthropathies
 Musculoskeletal 1.02 0.937 – 1.11 0.672 740 4466 exclusion phecode
714.1 Rheumatoid arthritis Musculoskeletal 1 0.913 – 1.1 0.938 558 3629 exclusion phecode
714.2 Juvenile rheumatoid arthritis Musculoskeletal 1.1 0.747 – 1.62 0.624 31 205 exclusion phecode
715 Other inflammatory spondylopathies Musculoskeletal 0.941 0.848 – 1.04 0.253 475 2808 exclusion phecode
715.1 Sacroiliitis NEC Musculoskeletal 0.947 0.76 – 1.18 0.624 105 672 exclusion phecode
715.2 Ankylosing spondylitis Musculoskeletal 1.02 0.782 – 1.33 0.893 70 475 exclusion phecode
716 Other arthropathies Musculoskeletal 1.01 0.973 – 1.06 0.505 4761 7475 exclusion phecode
716.1 Unspecified polyarthropathy or polyarthritis Musculoskeletal 1 0.792 – 1.26 0.995 104 511 exclusion phecode
716.2 Unspecified monoarthritis Musculoskeletal 0.998 0.739 – 1.35 0.989 61 291 exclusion phecode
716.9 Arthropathy NOS Musculoskeletal 1.01 0.972 – 1.06 0.525 4727 7474 exclusion phecode
717 Polymyalgia Rheumatica Musculoskeletal 0.944 0.767 – 1.16 0.582 117 730 exclusion phecode
720 Spinal stenosis Musculoskeletal 0.981 0.921 – 1.04 0.547 1375 6657 exclusion phecode
720.1 Spinal stenosis of lumbar region Musculoskeletal 0.966 0.898 – 1.04 0.353 1004 5484 exclusion phecode
721 Spondylosis and allied disorders Musculoskeletal 0.994 0.946 – 1.05 0.823 2327 7772 exclusion phecode
721.1 Spondylosis without myelopathy Musculoskeletal 0.992 0.942 – 1.04 0.745 2226 7691 exclusion phecode
721.2 Spondylosis with myelopathy Musculoskeletal 1.03 0.905 – 1.18 0.638 284 2000 exclusion phecode
721.8 Other allied disorders of spine Musculoskeletal 0.966 0.784 – 1.19 0.744 109 642 exclusion phecode
722 Intervertebral disc disorders Musculoskeletal 0.972 0.926 – 1.02 0.247 2457 8095 exclusion phecode
722.1 Displacement of intervertebral disc Musculoskeletal 0.982 0.925 – 1.04 0.543 1443 7425 exclusion phecode
722.3 Schmorl's nodes Musculoskeletal 1.33 0.957 – 1.85 0.0889 55 239 exclusion phecode
722.6 Degeneration of intervertebral disc Musculoskeletal 0.948 0.894 – 1 0.0683 1639 7338 exclusion phecode
722.7 Intervertebral disc disorder with myelopathy Musculoskeletal 0.948 0.795 – 1.13 0.551 172 1169 exclusion phecode
722.8 Postlaminectomy syndrome Musculoskeletal 1.06 0.873 – 1.29 0.551 131 947 exclusion phecode
722.9 Other and unspecified disc disorder Musculoskeletal 0.999 0.92 – 1.08 0.973 726 4694 exclusion phecode
723 Other disorders of cervical region Musculoskeletal 1.03 0.919 – 1.15 0.623 397 2284 exclusion phecode
723.1 Torticollis Musculoskeletal 1.03 0.841 – 1.26 0.774 118 606 exclusion phecode
724 Other and unspecified disorders of back Musculoskeletal 0.946 0.895 – 0.999 0.0449 1849 7659 exclusion phecode
724.1 Disorders of sacrum Musculoskeletal 0.927 0.866 – 0.993 0.0311 1140 5451 exclusion phecode
724.2 Disorders of coccyx Musculoskeletal 0.864 0.742 – 1.01 0.0583 246 1025 exclusion phecode
724.8 Other symptoms referable to back Musculoskeletal 0.868 0.774 – 0.972 0.0145 406 2195 exclusion phecode
724.9 Other unspecified back disorders Musculoskeletal 0.989 0.895 – 1.09 0.836 509 3254 exclusion phecode
726 Peripheral enthesopathies and allied syndromes Musculoskeletal 0.964 0.924 – 1.01 0.0879 4868 5588 exclusion phecode
726.1 Enthesopathy Musculoskeletal 0.973 0.929 – 1.02 0.235 3676 5565 exclusion phecode
726.2 Synoviopathy Musculoskeletal 0.949 0.853 – 1.06 0.338 463 1867 exclusion phecode
726.3 Bursitis Musculoskeletal 0.929 0.862 – 1 0.052 1028 3256 exclusion phecode
726.4 Calcaneal spur; Exostosis NOS Musculoskeletal 0.929 0.842 – 1.03 0.143 586 2205 exclusion phecode
727 Other disorders of synovium, tendon, and bursa Musculoskeletal 0.957 0.913 – 1 0.0617 3565 5559 exclusion phecode
727.1 Synovitis and tenosynovitis Musculoskeletal 0.988 0.929 – 1.05 0.704 1570 4694 exclusion phecode
727.2 Bursitis disorders Musculoskeletal 0.781 0.659 – 0.925 0.00422 217 781 exclusion phecode
727.4 Ganglion and cyst of synovium, tendon, and bursa Musculoskeletal 0.969 0.888 – 1.06 0.481 778 2654 exclusion phecode
727.5 Rupture of synovium Musculoskeletal 0.953 0.824 – 1.1 0.523 268 887 exclusion phecode
727.6 Rupture of tendon, nontraumatic Musculoskeletal 0.98 0.914 – 1.05 0.579 1181 3912 exclusion phecode
727.7 Contracture of tendon (sheath) Musculoskeletal 0.896 0.776 – 1.04 0.138 253 1110 exclusion phecode
727.8 Plica syndrome Musculoskeletal 0.935 0.637 – 1.37 0.731 41 222 exclusion phecode
728 Disorders of muscle, ligament, and fascia Musculoskeletal 0.966 0.914 – 1.02 0.231 1952 5398 exclusion phecode
728.1 Muscular calcification and ossification Musculoskeletal 1.22 0.796 – 1.86 0.364 30 158 exclusion phecode
728.2 Laxity of ligament or hypermobility syndrome Musculoskeletal 0.882 0.707 – 1.1 0.262 120 538 exclusion phecode
728.7 Fasciitis Musculoskeletal 0.918 0.864 – 0.976 0.00621 1606 4482 exclusion phecode
728.71
Contracture of palmar fascia [Dupuytren's
Contracture of palmar fascia [Dupuytren's disease]
 Musculoskeletal 0.969 0.833 – 1.13 0.687 235 856 exclusion phecode
729 Other disorders of soft tissues Musculoskeletal 0.966 0.909 – 1.03 0.259 1595 5004 exclusion phecode
729.1 Rheumatism, unspecified and fibrositis Musculoskeletal 0.916 0.633 – 1.32 0.639 38 142 exclusion phecode
729.3 Panniculitis Musculoskeletal 0.828 0.582 – 1.18 0.295 52 205 exclusion phecode
729.7 Nontraumatic compartment syndrome Musculoskeletal 1.05 0.669 – 1.64 0.838 25 126 exclusion phecode
731
Osteitis deformans and osteopathies associated
Osteitis deformans and osteopathies associated with other disorders classified elsewhere
 Musculoskeletal 1.04 0.808 – 1.33 0.784 84 535 exclusion phecode
732 Osteochondropathies Musculoskeletal 0.926 0.753 – 1.14 0.464 113 821 exclusion phecode
732.1 Juvenile osteochondrosis Musculoskeletal 0.779 0.595 – 1.02 0.0683 68 454 exclusion phecode
732.7 Osteochondritis dissecans Musculoskeletal 1.01 0.659 – 1.55 0.962 29 184 exclusion phecode
733 Other disorders of bone and cartilage Musculoskeletal 1 0.951 – 1.06 0.885 2234 6248 exclusion phecode
733.2 Cyst of bone Musculoskeletal 1.14 0.886 – 1.46 0.312 81 412 exclusion phecode
733.4 Aseptic necrosis of bone Musculoskeletal 0.874 0.724 – 1.06 0.161 151 1074 exclusion phecode
733.6 Costochondritis Musculoskeletal 0.921 0.777 – 1.09 0.34 209 869 exclusion phecode
733.8 Malunion and nonunion of fracture Musculoskeletal 0.968 0.832 – 1.13 0.679 216 1733 exclusion phecode
733.9 Chondromalacia Musculoskeletal 1.52 1.03 – 2.25 0.0342 31 187 exclusion phecode
735 Acquired foot deformities Musculoskeletal 0.979 0.926 – 1.03 0.447 1713 7699 exclusion phecode
735.1 Flat foot Musculoskeletal 0.941 0.83 – 1.07 0.35 311 1620 exclusion phecode
735.2 Acquired toe deformities Musculoskeletal 1.06 0.976 – 1.16 0.16 700 3423 exclusion phecode
735.21 Hammer toe (acquired) Musculoskeletal 1.01 0.911 – 1.13 0.789 437 2198 exclusion phecode
735.23 Hallux rigidus Musculoskeletal 1.23 1.05 – 1.43 0.0097 218 1120 exclusion phecode
735.3 Hallux valgus (Bunion) Musculoskeletal 0.968 0.895 – 1.05 0.425 815 3944 exclusion phecode
736 Other acquired deformities of limbs Musculoskeletal 0.958 0.898 – 1.02 0.186 1262 6792 exclusion phecode
736.1 Acquired deformities of forearm Musculoskeletal 1.08 0.757 – 1.53 0.686 42 238 exclusion phecode
736.2 Acquired deformities of finger Musculoskeletal 1.15 0.934 – 1.42 0.186 118 541 exclusion phecode
736.3 Acquired deformities of hip Musculoskeletal 1.07 0.666 – 1.72 0.782 21 116 exclusion phecode
736.4 Genu valgum or varum (acquired) Musculoskeletal 0.861 0.715 – 1.04 0.117 148 796 exclusion phecode
736.5 Acquired deformities of knee Musculoskeletal 0.961 0.772 – 1.2 0.723 105 616 exclusion phecode
736.6 Unequal leg length (acquired) Musculoskeletal 0.927 0.766 – 1.12 0.44 154 838 exclusion phecode
737 Curvature of spine Musculoskeletal 0.966 0.88 – 1.06 0.462 572 3747 exclusion phecode
737.1 Kyphosis (acquired) Musculoskeletal 0.876 0.733 – 1.05 0.144 156 1141 exclusion phecode
737.2 Lordosis (acquired) Musculoskeletal 0.976 0.584 – 1.63 0.927 21 160 exclusion phecode
737.3 Kyphoscoliosis and scoliosis Musculoskeletal 0.956 0.859 – 1.06 0.408 440 2887 exclusion phecode
738 Other acquired musculoskeletal deformity Musculoskeletal 1 0.925 – 1.09 0.928 763 5741 exclusion phecode
738.4 Acquired spondylolisthesis Musculoskeletal 0.983 0.873 – 1.11 0.771 355 2543 exclusion phecode
739 Contracture of joint Musculoskeletal 0.957 0.833 – 1.1 0.529 251 1514 exclusion phecode
740 Osteoarthrosis Musculoskeletal 1 0.96 – 1.04 0.983 5706 7000 exclusion phecode
740.1 Osteoarthritis; localized Musculoskeletal 0.963 0.917 – 1.01 0.136 3152 6324 exclusion phecode
740.11 Osteoarthrosis, localized, primary Musculoskeletal 0.966 0.917 – 1.02 0.178 2852 6058 exclusion phecode
740.12 Osteoarthrosis, localized, secondary Musculoskeletal 1.03 0.896 – 1.18 0.688 281 1514 exclusion phecode
740.2 Osteoarthrosis, generalized Musculoskeletal 0.963 0.883 – 1.05 0.394 814 2712 exclusion phecode
740.3
Osteoarthrosis involving more than one site
Osteoarthrosis involving more than one site, but not specified as generalized
 Musculoskeletal 1.06 0.889 – 1.27 0.497 174 752 exclusion phecode
740.9 Osteoarthrosis NOS Musculoskeletal 1 0.964 – 1.05 0.851 5453 6966 exclusion phecode
741 Symptoms and disorders of the joints Musculoskeletal 0.988 0.948 – 1.03 0.585 3600 8380 exclusion phecode
741.1 Ankylosis of joint Musculoskeletal 1.04 0.805 – 1.34 0.761 71 496 exclusion phecode
741.2 Stiffness of joint Musculoskeletal 0.995 0.905 – 1.09 0.914 565 2982 exclusion phecode
741.3 Difficulty in walking Musculoskeletal 0.997 0.929 – 1.07 0.935 1036 5211 exclusion phecode
741.4 Joint effusions Musculoskeletal 0.954 0.893 – 1.02 0.155 1228 5641 exclusion phecode
741.5 Hemarthrosis Musculoskeletal 0.818 0.587 – 1.14 0.234 45 240 exclusion phecode
741.6 Villonodular synovitis Musculoskeletal 1.11 0.729 – 1.7 0.616 30 147 exclusion phecode
742 Derangement of joint, non-traumatic Musculoskeletal 0.974 0.923 – 1.03 0.334 1840 7833 exclusion phecode
742.1 Loose body in joint Musculoskeletal 1.29 0.94 – 1.78 0.114 52 332 exclusion phecode
742.2
Pathological, developmental or recurrent
Pathological, developmental or recurrent dislocation
 Musculoskeletal 0.958 0.758 – 1.21 0.723 84 535 exclusion phecode
742.8 Articular cartilage disorder Musculoskeletal 0.913 0.727 – 1.15 0.431 92 529 exclusion phecode
742.9 Other derangement of joint Musculoskeletal 0.975 0.923 – 1.03 0.379 1742 7651 exclusion phecode
743
Osteoporosis, osteopenia and pathological
Osteoporosis, osteopenia and pathological fracture
 Musculoskeletal 0.96 0.919 – 1 0.0676 3927 8702 exclusion phecode
743.1 Osteoporosis Musculoskeletal 0.957 0.897 – 1.02 0.184 1624 4638 exclusion phecode
743.11 Osteoporosis NOS Musculoskeletal 0.96 0.9 – 1.02 0.222 1600 4581 exclusion phecode
743.12 Senile osteoporosis Musculoskeletal 0.937 0.826 – 1.06 0.308 423 1097 exclusion phecode
743.13 Other specified osteoporosis Musculoskeletal 1.04 0.866 – 1.24 0.686 173 666 exclusion phecode
743.2 Pathologic fracture Musculoskeletal 0.956 0.862 – 1.06 0.393 490 2241 exclusion phecode
743.21 Pathologic fracture of vertebrae Musculoskeletal 0.985 0.837 – 1.16 0.851 192 951 exclusion phecode
743.22 Pathologic fracture of femur Musculoskeletal 0.891 0.649 – 1.22 0.473 59 288 exclusion phecode
743.4 Stress fracture Musculoskeletal 0.94 0.806 – 1.1 0.434 208 1062 exclusion phecode
743.9
Osteopenia or other disorder of bone and
Osteopenia or other disorder of bone and cartilage
 Musculoskeletal 0.946 0.903 – 0.991 0.0184 3241 8269 exclusion phecode
745 Pain in joint Musculoskeletal 0.977 0.94 – 1.02 0.248 8313 4534 exclusion phecode
747 Cardiac and circulatory congenital anomalies Congenital Anomalies 0.997 0.929 – 1.07 0.929 1036 5825 exclusion phecode
747.1 Cardiac congenital anomalies Congenital Anomalies 1 0.925 – 1.08 1 866 4575 exclusion phecode
747.11 Cardiac shunt/ heart septal defect Congenital Anomalies 0.999 0.88 – 1.13 0.982 336 1706 exclusion phecode
747.12 Valvular heart disease/ heart chambers Congenital Anomalies 1.11 0.99 – 1.24 0.0738 416 1969 exclusion phecode
747.13 Congenital anomalies of great vessels Congenital Anomalies 1.06 0.896 – 1.25 0.505 189 1035 exclusion phecode
747.2
Congenital anomalies of peripheral vascular
Congenital anomalies of peripheral vascular system
 Congenital Anomalies 1 0.852 – 1.18 0.985 189 1298 exclusion phecode
748 Anomalies of respiratory system, congenital Congenital Anomalies 0.923 0.636 – 1.34 0.676 35 297 exclusion phecode
749 Congenital anomalies of face and neck Congenital Anomalies 1 0.843 – 1.19 0.98 163 1298 exclusion phecode
749.1 Cleft palate Congenital Anomalies 0.615 0.317 – 1.19 0.15 7 165 exclusion phecode
749.2 Congenital anomalies of skull and face bones Congenital Anomalies 1.14 0.775 – 1.67 0.51 32 235 exclusion phecode
750 Digestive congenital anomalies Congenital Anomalies 1 0.898 – 1.12 0.939 389 2385 exclusion phecode
750.1 Upper gastrointestinal congenital anomalies Congenital Anomalies 0.973 0.798 – 1.19 0.785 123 966 exclusion phecode
750.11 Esophageal atresia/tracheoesophageal fistula Congenital Anomalies 0.97 0.712 – 1.32 0.846 55 322 exclusion phecode
750.13 Congenital anomalies of mouth/tongue Congenital Anomalies 0.845 0.561 – 1.27 0.42 28 223 exclusion phecode
750.14 Congenital anomalies of esophagus Congenital Anomalies 1.07 0.783 – 1.46 0.677 51 355 exclusion phecode
750.15 Congenital anomalies of stomach Congenital Anomalies 1.11 0.686 – 1.81 0.664 18 156 exclusion phecode
750.2 Lower gastrointestinal congenital anomalies Congenital Anomalies 1.02 0.893 – 1.17 0.731 267 1470 exclusion phecode
750.21 Congenital anomalies of intestine Congenital Anomalies 0.981 0.827 – 1.16 0.828 170 854 exclusion phecode
750.22
Congenital anomaly of gallbladder, bile ducts
Congenital anomaly of gallbladder, bile ducts, liver, pancreas
 Congenital Anomalies 1.22 0.976 – 1.53 0.0803 102 615 exclusion phecode
751 Genitourinary congenital anomalies Congenital Anomalies 0.99 0.912 – 1.08 0.821 749 5206 exclusion phecode
751.1 Congenital anomalies of genital organs Congenital Anomalies 1.05 0.906 – 1.21 0.531 246 1547 exclusion phecode
751.11 Congenital anomalies of female genital organs Congenital Anomalies 1.02 0.867 – 1.21 0.777 191 1094 exclusion phecode
751.12 Congenital anomalies of male genital organs Congenital Anomalies 1.22 0.903 – 1.65 0.196 42 348 exclusion phecode
751.2 Congenital anomalies of urinary system Congenital Anomalies 0.95 0.859 – 1.05 0.316 497 3548 exclusion phecode
751.21 Cystic kidney disease Congenital Anomalies 0.954 0.85 – 1.07 0.42 376 2563 exclusion phecode
751.22 Other specified congenital anomalies of kidney Congenital Anomalies 0.837 0.659 – 1.06 0.144 84 760 exclusion phecode
751.3 Obstructive genitourinary defect Congenital Anomalies 0.857 0.62 – 1.19 0.351 44 452 exclusion phecode
752 Nervous system congenital anomalies Congenital Anomalies 0.947 0.84 – 1.07 0.374 339 2994 exclusion phecode
752.1 Neural tube defects Congenital Anomalies 0.979 0.857 – 1.12 0.758 265 2439 exclusion phecode
752.11 Spina bifida Congenital Anomalies 0.784 0.56 – 1.1 0.157 46 419 exclusion phecode
752.2
Other specified congenital anomalies of nervous
Other specified congenital anomalies of nervous system
 Congenital Anomalies 0.806 0.606 – 1.07 0.137 71 565 exclusion phecode
753 Congenital anomalies of the eye Congenital Anomalies 1.1 0.875 – 1.38 0.415 89 639 exclusion phecode
753.1 Congenital cataract and lens anomalies Congenital Anomalies 1.04 0.689 – 1.57 0.846 24 183 exclusion phecode
753.2 Congenital anomalies of posterior segment of eye Congenital Anomalies 1.13 0.739 – 1.72 0.575 28 179 exclusion phecode
754 Congenital musculoskeletal deformities of spine Congenital Anomalies 0.986 0.883 – 1.1 0.793 404 3171 exclusion phecode
754.1 Lumbosacral spondylolysis, congenital Congenital Anomalies 0.775 0.58 – 1.04 0.0856 59 379 exclusion phecode
754.2 Spondylolisthesis, congenital Congenital Anomalies 0.94 0.799 – 1.11 0.456 179 1496 exclusion phecode
755 Congenital anomalies of limbs Congenital Anomalies 1.09 0.96 – 1.24 0.186 304 2024 exclusion phecode
755.1 Congenital deformities of feet Congenital Anomalies 1.05 0.88 – 1.25 0.6 163 1009 exclusion phecode
755.4
Congenital anomalies of upper limb, including
Congenital anomalies of upper limb, including shoulder girdle
 Congenital Anomalies 0.891 0.57 – 1.39 0.613 27 202 exclusion phecode
755.6
Other congenital anomalies of lower limb
Other congenital anomalies of lower limb, including pelvic girdle
 Congenital Anomalies 1.15 0.938 – 1.41 0.178 115 799 exclusion phecode
755.61 Congenital hip dysplasia and deformity Congenital Anomalies 1.2 0.908 – 1.58 0.201 63 470 exclusion phecode
756 Other congenital musculoskeletal anomalies Congenital Anomalies 0.976 0.884 – 1.08 0.635 504 3433 exclusion phecode
756.1 Congenital anomalies of abdominal wall; diaphram Congenital Anomalies 0.985 0.632 – 1.54 0.947 24 174 exclusion phecode
756.2
Pectus and other congenital anomalies of
Pectus and other congenital anomalies of ribs/sternum
 Congenital Anomalies 1.04 0.644 – 1.68 0.874 24 128 exclusion phecode
756.3
Congenital anomalies of muscle, tendon, fascia
Congenital anomalies of muscle, tendon, fascia, and connective tissue
 Congenital Anomalies 0.958 0.795 – 1.15 0.65 142 827 exclusion phecode
756.5 Congenital osteodystrophies Congenital Anomalies 0.974 0.868 – 1.09 0.655 369 2626 exclusion phecode
757 Congenital anomalies of the integument Congenital Anomalies 1.17 0.968 – 1.41 0.106 137 1094 exclusion phecode
758 Chromosomal anomalies and genetic disorders Congenital Anomalies 1.05 0.819 – 1.36 0.683 80 509 exclusion phecode
758.1 Chromosomal anomalies Congenital Anomalies 1.17 0.875 – 1.57 0.286 58 383 exclusion phecode
759 Other and unspecified congenital anomalies Congenital Anomalies 0.91 0.778 – 1.06 0.238 213 1469 exclusion phecode
759.1 Anomalies of endocrine glands, congenital Congenital Anomalies 1.13 0.719 – 1.77 0.601 24 197 exclusion phecode
760 Back pain Symptoms 0.995 0.959 – 1.03 0.79 6723 6123 exclusion phecode
761 Cervicalgia Symptoms 0.987 0.945 – 1.03 0.545 3081 9678 exclusion phecode
763
Thoracic or lumbosacral neuritis or
Thoracic or lumbosacral neuritis or radiculitis, unspecified
 Symptoms 0.965 0.911 – 1.02 0.235 1534 8042 exclusion phecode
764 Sciatica Symptoms 0.992 0.936 – 1.05 0.782 1533 8129 exclusion phecode
765 Cervical radiculitis Symptoms 0.978 0.904 – 1.06 0.584 811 4565 exclusion phecode
766 Neuralgia, neuritis, and radiculitis NOS Symptoms 0.966 0.918 – 1.02 0.183 2081 9098 exclusion phecode
767 Cervicocranial/Cervicobrachial syndrome Symptoms 1.05 0.782 – 1.41 0.741 64 327 exclusion phecode
769 Nonallopathic lesions NEC Symptoms 0.942 0.857 – 1.03 0.21 585 3208 exclusion phecode
770 Myalgia and myositis unspecified Symptoms 0.997 0.949 – 1.05 0.899 2296 9048 exclusion phecode
771 Musculoskeletal symptoms referable to limbs Symptoms 1.02 0.969 – 1.08 0.431 1939 8299 exclusion phecode
771.1 Swelling of limb Symptoms 0.972 0.927 – 1.02 0.249 2557 8379 exclusion phecode
771.2 Cramp of limb Symptoms 1.01 0.91 – 1.11 0.905 546 2671 exclusion phecode
772 Symptoms of the muscles Symptoms 0.94 0.874 – 1.01 0.0903 1005 5224 exclusion phecode
772.1 Muscular wasting and disuse atrophy Symptoms 0.894 0.74 – 1.08 0.247 157 896 exclusion phecode
772.2 Spasm of muscle Symptoms 0.942 0.877 – 1.01 0.0989 1017 5813 exclusion phecode
772.3 Muscle weakness Symptoms 1.07 1 – 1.14 0.0383 1259 6870 exclusion phecode
772.4 Rhabdomyolysis Symptoms 1.03 0.789 – 1.35 0.815 66 375 exclusion phecode
772.6 Facial weakness Symptoms 1.23 1.06 – 1.43 0.00729 217 1208 exclusion phecode
780 Hypothermia/Chills Symptoms 1.04 0.885 – 1.21 0.66 205 1259 exclusion phecode
781
Symptoms involving nervous and musculoskeletal
Symptoms involving nervous and musculoskeletal systems
 Symptoms 1.08 1.01 – 1.15 0.0186 1212 7005 exclusion phecode
781.1 Loss of height Symptoms 0.959 0.737 – 1.25 0.757 73 356 exclusion phecode
781.2 Abnormal posture Symptoms 1.12 0.751 – 1.66 0.586 24 143 exclusion phecode
782.3 Edema Symptoms 1.02 0.976 – 1.07 0.352 2569 9074 exclusion phecode
782.6 Pallor and flushing Symptoms 0.992 0.89 – 1.11 0.883 442 2479 exclusion phecode
783 Fever of unknown origin Symptoms 1.05 1 – 1.1 0.044 2465 10252 exclusion phecode
783.1 Postprocedural fever Symptoms 0.984 0.785 – 1.23 0.889 102 698 exclusion phecode
785 Abdominal pain Symptoms 1.02 0.981 – 1.06 0.331 7009 5835 exclusion phecode
788 Syncope and collapse Symptoms 0.973 0.923 – 1.03 0.322 1837 9241 exclusion phecode
789 Nausea and vomiting Symptoms 1.04 1 – 1.09 0.032 4015 8784 exclusion phecode
789.1 Persistent vomiting Symptoms 1.1 0.964 – 1.25 0.159 310 1882 exclusion phecode
790 Nonspecific findings on examination of blood Symptoms 1.04 0.97 – 1.11 0.275 1099 5362 exclusion phecode
790.1 Elevated sedimentation rate Symptoms 0.903 0.718 – 1.14 0.385 104 590 exclusion phecode
790.6 Other abnormal blood chemistry Symptoms 1.06 1.02 – 1.1 0.00765 3649 8726 exclusion phecode
790.8 Elevated C-reactive protein (CRP) Symptoms 1.19 0.969 – 1.45 0.0971 123 721 exclusion phecode
790.9 Abnormal arterial blood gases Symptoms 1.07 0.811 – 1.42 0.618 60 346 exclusion phecode
791 Gangrene Symptoms 0.962 0.787 – 1.18 0.708 117 865 exclusion phecode
792
Abnormal Papanicolaou smear of cervix and
Abnormal Papanicolaou smear of cervix and cervical HPV
 Genitourinary 0.981 0.919 – 1.05 0.58 1382 3444 exclusion phecode
792.1
Papanicolaou smear of cervix or vagina with
Papanicolaou smear of cervix or vagina with atypical squamous cells
 Genitourinary 0.996 0.902 – 1.1 0.942 540 2238 exclusion phecode
794
Abnormal results of other function studies
Abnormal results of other function studies (bladder, pancreas, placenta, spleen, etc)
 Symptoms 1.05 0.88 – 1.25 0.602 151 1381 exclusion phecode
795
Other and nonspecific abnormal cytological
Other and nonspecific abnormal cytological, histological and immunological findings
 Symptoms 1.01 0.939 – 1.09 0.776 935 5604 exclusion phecode
795.8 Abnormal tumor markers Symptoms 1.04 0.947 – 1.14 0.429 571 4084 exclusion phecode
795.81 Elevated carcinoembryonic antigen [CEA] Symptoms 1.12 0.709 – 1.77 0.626 22 169 exclusion phecode
795.82 Elevated cancer antigen 125 [CA 125] Symptoms 1.13 0.864 – 1.47 0.377 61 528 exclusion phecode
796 Elevated prostate specific antigen [PSA] Genitourinary 0.983 0.897 – 1.08 0.723 752 2257 exclusion phecode
797 Shock Symptoms 1.17 1.03 – 1.34 0.0147 299 1539 exclusion phecode
797.1 Cardiogenic shock Symptoms 1.15 0.951 – 1.4 0.147 140 625 exclusion phecode
798 Malaise and fatigue Symptoms 1.04 1 – 1.08 0.0494 5463 7379 exclusion phecode
798.1 Chronic fatigue syndrome Symptoms 1 0.927 – 1.09 0.944 878 3953 exclusion phecode
800 Fracture of lower limb Injuries & Poisonings 0.984 0.915 – 1.06 0.671 932 5641 exclusion phecode
800.1 Fracture of neck of femur Injuries & Poisonings 1.06 0.908 – 1.23 0.47 211 1183 exclusion phecode
800.2 Fracture of unspecified part of femur Injuries & Poisonings 1.12 0.98 – 1.29 0.095 259 1534 exclusion phecode
800.3 Fracture of tibia and fibula Injuries & Poisonings 1.01 0.897 – 1.14 0.867 338 2119 exclusion phecode
800.4 Fracture of patella Injuries & Poisonings 0.827 0.689 – 0.992 0.0411 170 869 exclusion phecode
801 Fracture of ankle and foot Injuries & Poisonings 0.916 0.855 – 0.981 0.0117 1116 5861 exclusion phecode
801.1 Fracture of foot Injuries & Poisonings 0.914 0.825 – 1.01 0.0861 467 2827 exclusion phecode
802 Fracture of pelvis Injuries & Poisonings 0.804 0.668 – 0.968 0.0211 146 879 exclusion phecode
803 Fracture of upper limb Injuries & Poisonings 0.942 0.874 – 1.02 0.124 883 4988 exclusion phecode
803.1 Fracture of humerus Injuries & Poisonings 0.869 0.76 – 0.993 0.0388 280 1735 exclusion phecode
803.2 Fracture of radius and ulna Injuries & Poisonings 0.928 0.841 – 1.02 0.134 536 2823 exclusion phecode
803.21 Colles' fracture Injuries & Poisonings 0.914 0.755 – 1.11 0.358 154 705 exclusion phecode
803.3 Fracture of clavicle or scapula Injuries & Poisonings 0.972 0.829 – 1.14 0.727 192 1159 exclusion phecode
804 Fracture of hand or wrist Injuries & Poisonings 0.944 0.869 – 1.03 0.171 756 3926 exclusion phecode
805
Fracture of vertebral column without mention of
Fracture of vertebral column without mention of spinal cord injury
 Injuries & Poisonings 0.983 0.892 – 1.08 0.739 510 3141 exclusion phecode
807 Fracture of ribs Injuries & Poisonings 1.04 0.924 – 1.18 0.501 328 1612 exclusion phecode
809 Fracture of unspecified bones Injuries & Poisonings 0.977 0.914 – 1.04 0.49 1105 7013 exclusion phecode
816 Cerebral laceration and contusion Injuries & Poisonings 1.06 0.559 – 2.01 0.856 14 123 exclusion phecode
817 Concussion Injuries & Poisonings 1.05 0.945 – 1.17 0.365 458 2602 exclusion phecode
818 Intracranial hemorrhage (injury) Injuries & Poisonings 0.98 0.81 – 1.19 0.839 132 824 exclusion phecode
818.1 Subdural hemorrhage (injury) Injuries & Poisonings 0.947 0.674 – 1.33 0.756 42 226 exclusion phecode
818.2 Subarachnoid hemorrhage (injury) Injuries & Poisonings 1.19 0.792 – 1.79 0.402 32 274 exclusion phecode
819
Skull and face fracture and other intercranial
Skull and face fracture and other intercranial injury
 Injuries & Poisonings 1.09 1.01 – 1.18 0.0212 857 5773 exclusion phecode
830 Dislocation Injuries & Poisonings 0.961 0.91 – 1.02 0.163 1687 8697 exclusion phecode
835 Internal derangement of knee Injuries & Poisonings 0.929 0.865 – 0.997 0.0411 1044 5518 exclusion phecode
836 Traumatic arthropathy Injuries & Poisonings 1.01 0.854 – 1.19 0.931 192 1150 exclusion phecode
840 Sprains and strains Injuries & Poisonings 0.959 0.92 – 0.999 0.045 3660 8682 exclusion phecode
840.1 Muscle/tendon sprain Injuries & Poisonings 0.941 0.818 – 1.08 0.397 275 1223 exclusion phecode
840.2 Rotator cuff (capsule) sprain Injuries & Poisonings 0.948 0.871 – 1.03 0.216 766 3764 exclusion phecode
840.3 Joint/ligament sprain Injuries & Poisonings 0.978 0.916 – 1.04 0.499 1223 5677 exclusion phecode
841 Sprains and strains of back and neck Injuries & Poisonings 0.923 0.853 – 1 0.0486 883 3855 exclusion phecode
842 Other sprains and strains Injuries & Poisonings 0.945 0.869 – 1.03 0.195 734 3309 exclusion phecode
850 Hemorrhage or hematoma complicating a procedure Injuries & Poisonings 1.09 1 – 1.18 0.05 725 5180 exclusion phecode
851
Complications of transplants and reattached
Complications of transplants and reattached limbs
 Injuries & Poisonings 1.11 1.03 – 1.19 0.00363 1032 6763 exclusion phecode
853 Complication of colostomy or enterostomy Injuries & Poisonings 1.22 1.03 – 1.45 0.0237 173 1079 exclusion phecode
854
Complications of cardiac/vascular device
Complications of cardiac/vascular device, implant, and graft
 Injuries & Poisonings 1.09 1.01 – 1.18 0.0315 787 4872 exclusion phecode
855
Complication of nervous system device, implant
Complication of nervous system device, implant, and graft
 Injuries & Poisonings 1.36 1.02 – 1.83 0.0387 53 645 exclusion phecode
856
Vascular complications of surgery and medical
Vascular complications of surgery and medical procedures
 Injuries & Poisonings 1.23 1.01 – 1.51 0.0427 130 729 exclusion phecode
857
Mechanical complication of unspecified
Mechanical complication of unspecified genitourinary device, implant, and graft
 Injuries & Poisonings 1.07 0.955 – 1.2 0.248 403 3343 exclusion phecode
858 Complication of internal orthopedic device Injuries & Poisonings 0.991 0.904 – 1.09 0.841 571 5169 exclusion phecode
859
Complication due to other implant and internal
Complication due to other implant and internal device
 Injuries & Poisonings 1.17 1.07 – 1.27 0.000426 660 5262 exclusion phecode
860 Bone marrow or stem cell transplant Neoplasms 1.67 1.23 – 2.25 0.000882 63 456 exclusion phecode
870 Open wounds of head; neck; and trunk Injuries & Poisonings 1.08 1.02 – 1.15 0.00806 1475 9166 exclusion phecode
870.1 Open wound or laceration of eye or eyelid Injuries & Poisonings 1.25 0.969 – 1.61 0.0862 84 524 exclusion phecode
870.2 Open wound of ear Injuries & Poisonings 1.24 0.904 – 1.7 0.182 58 339 exclusion phecode
870.3 Other open wound of head and face Injuries & Poisonings 1.08 0.981 – 1.2 0.111 510 3314 exclusion phecode
870.4 Open wound of nose and sinus Injuries & Poisonings 1.1 0.838 – 1.45 0.483 64 506 exclusion phecode
870.5 Open wound of lip and mouth Injuries & Poisonings 1.16 0.91 – 1.49 0.226 80 663 exclusion phecode
870.6 Open wound of neck Injuries & Poisonings 1.45 1.01 – 2.08 0.0417 37 483 exclusion phecode
870.8 Open wound of genital organs Injuries & Poisonings 1 0.715 – 1.41 0.988 44 403 exclusion phecode
871 Open wounds of extremities Injuries & Poisonings 1.03 0.976 – 1.09 0.264 1546 8457 exclusion phecode
871.1 Open wound of hand except finger(s) Injuries & Poisonings 0.938 0.819 – 1.07 0.357 281 1474 exclusion phecode
871.2 Open wound of finger(s) Injuries & Poisonings 1.05 0.951 – 1.17 0.324 518 2741 exclusion phecode
871.3 Open wound of foot except toe(s) alone Injuries & Poisonings 1.09 0.921 – 1.28 0.328 192 1332 exclusion phecode
871.4 Open wound of toe(s) Injuries & Poisonings 0.956 0.794 – 1.15 0.635 140 871 exclusion phecode
872 Traumatic amputation Injuries & Poisonings 0.944 0.791 – 1.13 0.522 154 1362 exclusion phecode
874 Complication of amputation stump Injuries & Poisonings 0.845 0.615 – 1.16 0.298 47 446 exclusion phecode
875 Non-healing surgical wound Injuries & Poisonings 1.04 0.882 – 1.24 0.617 159 1358 exclusion phecode
876
Posttraumatic wound infection not elsewhere
Posttraumatic wound infection not elsewhere classified
 Injuries & Poisonings 1.04 0.905 – 1.19 0.581 254 2040 exclusion phecode
907 Injuries to the nervous system Injuries & Poisonings 1.02 0.903 – 1.16 0.715 309 2540 exclusion phecode
910 Superficial injury, infected Injuries & Poisonings 1.12 0.838 – 1.5 0.445 60 326 exclusion phecode
911 Blister Injuries & Poisonings 0.941 0.788 – 1.12 0.504 147 967 exclusion phecode
912 Insect bite Injuries & Poisonings 0.92 0.81 – 1.05 0.201 313 1533 exclusion phecode
913 Toxic effect of venom Injuries & Poisonings 1.1 0.942 – 1.29 0.224 218 1021 exclusion phecode
916 Contusion Injuries & Poisonings 1 0.953 – 1.05 0.948 2166 9659 exclusion phecode
930 Allergic reaction to food Injuries & Poisonings 0.952 0.841 – 1.08 0.438 358 1471 exclusion phecode
931
Contact dermatitis and other eczema due to
Contact dermatitis and other eczema due to plants [except food]
 Dermatologic 0.928 0.826 – 1.04 0.214 426 1519 exclusion phecode
938 Dermatitis due to solar radiation Dermatologic 0.984 0.938 – 1.03 0.512 3027 5527 exclusion phecode
938.1 Acute dermatitis due to solar radiation Dermatologic 0.851 0.683 – 1.06 0.153 113 440 exclusion phecode
938.2 Chronic dermatitis due to solar radiation Dermatologic 0.982 0.935 – 1.03 0.47 2938 5470 exclusion phecode
939
Atopic/contact dermatitis due to other or
Atopic/contact dermatitis due to other or unspecified
 Dermatologic 0.95 0.909 – 0.993 0.0233 3615 6017 exclusion phecode
939.1 Contact and allergic dermatitis of eyelid Dermatologic 0.866 0.631 – 1.19 0.376 61 181 exclusion phecode
941 Adverse reaction to serum or vaccine Injuries & Poisonings 1.07 0.83 – 1.37 0.618 80 391 exclusion phecode
942 Infusion and transfusion reaction Injuries & Poisonings 1.09 0.896 – 1.33 0.385 123 491 exclusion phecode
946 Anaphylactic shock NOS Injuries & Poisonings 0.951 0.826 – 1.1 0.49 264 1032 exclusion phecode
947 Urticaria Dermatologic 0.981 0.892 – 1.08 0.686 627 2374 exclusion phecode
949 Allergies, other Injuries & Poisonings 0.946 0.904 – 0.99 0.0173 3420 6021 exclusion phecode
952
Spinal cord injury without evidence of spinal
Spinal cord injury without evidence of spinal bone injury
 Injuries & Poisonings 1.08 0.907 – 1.3 0.375 153 1270 exclusion phecode
957 Injury to other and unspecified nerves Injuries & Poisonings 0.663 0.475 – 0.924 0.0154 46 340 exclusion phecode
958
Certain early complications of trauma or
Certain early complications of trauma or procedure
 Injuries & Poisonings 1.04 0.935 – 1.16 0.473 425 3186 exclusion phecode
958.1 Postoperative shock Injuries & Poisonings 0.975 0.76 – 1.25 0.844 83 424 exclusion phecode
958.2 Traumatic and surgical subcutaneous emphysema Injuries & Poisonings 1.45 1 – 2.09 0.0493 39 289 exclusion phecode
960 Poisoning by antibiotics Injuries & Poisonings 1.02 0.95 – 1.1 0.536 875 5523 exclusion phecode
960.1
Adverse effects of antibacterials (not
Adverse effects of antibacterials (not penicillins)
 Injuries & Poisonings 1.09 0.904 – 1.31 0.374 153 912 exclusion phecode
960.2 Allergy/adverse effect of penicillin Injuries & Poisonings 0.994 0.905 – 1.09 0.9 552 3967 exclusion phecode
961 Poisoning by other anti-infectives Injuries & Poisonings 1.01 0.875 – 1.18 0.846 237 1361 exclusion phecode
961.1 Poisoning/allergy of sulfonamides Injuries & Poisonings 0.983 0.874 – 1.11 0.781 336 2671 exclusion phecode
962 Poisoning by hormones and synthetic substitutes Injuries & Poisonings 0.948 0.84 – 1.07 0.391 349 2152 exclusion phecode
962.1
Adrenal cortical steroids causing adverse
Adrenal cortical steroids causing adverse effects in therapeutic use
 Injuries & Poisonings 1.06 0.885 – 1.26 0.545 173 991 exclusion phecode
962.2
Insulins and antidiabetic agents causing
Insulins and antidiabetic agents causing adverse effects in therapeutic use
 Injuries & Poisonings 1.02 0.688 – 1.52 0.917 33 254 exclusion phecode
962.3
Hormones and synthetic substitutes causing
Hormones and synthetic substitutes causing adverse effects in therapeutic use
 Injuries & Poisonings 0.935 0.797 – 1.1 0.41 203 1266 exclusion phecode
963 Poisoning by primarily systemic agents Injuries & Poisonings 1.01 0.934 – 1.08 0.872 873 5947 exclusion phecode
963.1
Antineoplastic and immunosuppressive drugs
Antineoplastic and immunosuppressive drugs causing adverse effects
 Injuries & Poisonings 1.01 0.935 – 1.09 0.811 841 5829 exclusion phecode
964
Poisoning by agents primarily affecting blood
Poisoning by agents primarily affecting blood constituents
 Injuries & Poisonings 0.988 0.88 – 1.11 0.844 368 1895 exclusion phecode
964.1 Anticoagulants causing adverse effects Injuries & Poisonings 0.952 0.844 – 1.07 0.422 350 1791 exclusion phecode
965
Poisoning by analgesics, antipyretics, and
Poisoning by analgesics, antipyretics, and antirheumatics
 Injuries & Poisonings 1.04 0.924 – 1.18 0.485 316 2098 exclusion phecode
965.1
Opiates and related narcotics causing adverse
Opiates and related narcotics causing adverse effects in therapeutic use
 Injuries & Poisonings 1.05 0.947 – 1.16 0.364 462 3586 exclusion phecode
965.3
Salicylates causing adverse effects in
Salicylates causing adverse effects in therapeutic use
 Injuries & Poisonings 1.03 0.745 – 1.43 0.849 49 277 exclusion phecode
966
Poisoning by anticonvulsants and
Poisoning by anticonvulsants and anti-Parkinsonism drugs
 Injuries & Poisonings 1.22 0.865 – 1.73 0.256 37 257 exclusion phecode
967
Adverse effects of sedatives or other central
Adverse effects of sedatives or other central nervous system depressants and anesthetics
 Injuries & Poisonings 1.04 0.934 – 1.16 0.481 410 3144 exclusion phecode
969 Poisoning by psychotropic agents Injuries & Poisonings 1.2 0.953 – 1.5 0.122 105 706 exclusion phecode
971
Poisoning by drugs primarily affecting the
Poisoning by drugs primarily affecting the autonomic nervous system
 Injuries & Poisonings 1.1 0.75 – 1.61 0.631 41 162 exclusion phecode
972
Poisoning by agents primarily affecting the
Poisoning by agents primarily affecting the cardiovascular system
 Injuries & Poisonings 1.14 0.944 – 1.37 0.174 147 715 exclusion phecode
972.1
Cardiac rhythm regulators causing adverse
Cardiac rhythm regulators causing adverse effects in therapeutic use
 Injuries & Poisonings 0.86 0.619 – 1.2 0.369 52 201 exclusion phecode
972.6 Antihypertensive agents causing adverse effects Injuries & Poisonings 1.26 0.916 – 1.74 0.155 50 269 exclusion phecode
974
Poisoning by water, mineral, and uric acid
Poisoning by water, mineral, and uric acid metabolism drugs
 Injuries & Poisonings 0.863 0.638 – 1.17 0.338 59 287 exclusion phecode
975
Poisoning by agents primarily acting on the
Poisoning by agents primarily acting on the smooth and skeletal muscles and respiratory system
 Injuries & Poisonings 0.743 0.513 – 1.08 0.115 38 185 exclusion phecode
976
Poisoning by agents primarily affecting skin &
Poisoning by agents primarily affecting skin & mucous membrane, ophthalmological, otorhinolaryngological, & dental drugs
 Injuries & Poisonings 1.38 0.921 – 2.06 0.118 32 195 exclusion phecode
977 Personal history of allergy to medicinal agents Injuries & Poisonings 1.06 0.971 – 1.15 0.197 655 4168 exclusion phecode
979 Adverse drug events and drug allergies Injuries & Poisonings 1.09 1.02 – 1.15 0.00681 1437 7848 exclusion phecode
980
Encounter for long-term (current) use of
Encounter for long-term (current) use of antibiotics
 Infectious Diseases 1.09 0.98 – 1.2 0.114 468 3793 exclusion phecode
985 Toxic effect of other metals Injuries & Poisonings 0.793 0.499 – 1.26 0.327 22 168 exclusion phecode
989
Toxic effect of other substances, chiefly
Toxic effect of other substances, chiefly nonmedicinal as to source
 Injuries & Poisonings 1.19 0.918 – 1.56 0.186 71 398 exclusion phecode
990 Effects radiation NOS Injuries & Poisonings 1.02 0.951 – 1.09 0.588 1048 8211 exclusion phecode
994 Sepsis and SIRS Injuries & Poisonings 1.14 1.06 – 1.23 0.000608 881 5735 exclusion phecode
994.1 Systemic inflammatory response syndrome (SIRS) Injuries & Poisonings 0.972 0.792 – 1.19 0.785 112 772 exclusion phecode
994.2 Sepsis Injuries & Poisonings 1.14 1.06 – 1.23 0.000845 836 5463 exclusion phecode
994.21 Septic shock Injuries & Poisonings 1.24 1.08 – 1.42 0.0027 265 1585 exclusion phecode
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