prs_id	slug	legacy_id	legacy_model	prswebprefix	trait_code	trait_name	trait_type	description	cohort	cohort_label	method	gwas_source	reference_label	reference_url	snp_count	p_value	pseudo_r2	brier_score	mse	aauc	aauc_ci	effect_metric	top_effect_1	top_effect_1_ci	top_or_1	top_or_1_ci	top_effect_2	top_effect_2_ci	top_or_2	top_or_2_ci	top_effect_5	top_effect_5_ci	top_or_5	top_or_5_ci	top_effect_10	top_effect_10_ci	top_or_10	top_or_10_ci	top_effect_25	top_effect_25_ci	top_or_25	top_or_25_ci	q1_vs_q2_effect	q1_vs_q2_effect_ci	q1_vs_q2_p_value	q1_vs_q3_effect	q1_vs_q3_effect_ci	q1_vs_q3_p_value	q1_vs_q4_effect	q1_vs_q4_effect_ci	q1_vs_q4_p_value	nominally_significant	reversed_effect_warning	underpowered_warning	upload_to_portal	sex	cases	controls	genome_build	tuning_parameter	weights_external_url	weights_url	phewas_download_url	exclusion_download_url	last_updated
prsweb-phecode149-4-20001-1006-p-5e-05-mgi-20200608	prsweb-phecode149-4-20001-1006-p-5e-05-mgi-20200608	PRSWEB_PHECODE149.4_20001-1006_P_5e-05_MGI_20200608	P_5e-05	PRSWEB_PHECODE149.4_20001-1006_P_5e-05_MGI_20200608	149.4	Cancer code, self-reported: larynx/throat cancer	Binary	GWAS round 2: Results shared 1st August 2018. Imputed genotypes from HRC plus UK10K & 1000 Genomes reference panels as released by UK Biobank in March 2018.	MGI	Michigan Genomics Initiative	Fixed threshold (5e-05)	UKB GWAS (PHESANT)	UKB_GWAS	https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761	72	0.87	0.00108064	0.0826		0.506	0.464-0.552	OR	1.51	0.383-5.95	1.51	0.383-5.95	0.758	0.205-2.8	0.758	0.205-2.8	0.805	0.357-1.82	0.805	0.357-1.82	0.768	0.423-1.4	0.768	0.423-1.4	1.02	0.706-1.49	1.02	0.706-1.49	0.997	0.624-1.59	0.991	1.15	0.733-1.81	0.537	1.05	0.665-1.67	0.823	False	False	False	False	Both	158	1580	GRCh37/hg19	P<=5e-05					2020-06-08
prsweb-phecode149-4-c3-larynx-p-5e-05-mgi-20200608	prsweb-phecode149-4-c3-larynx-p-5e-05-mgi-20200608	PRSWEB_PHECODE149.4_C3-LARYNX_P_5e-05_MGI_20200608	P_5e-05	PRSWEB_PHECODE149.4_C3-LARYNX_P_5e-05_MGI_20200608	149.4	Malignant neoplasm of larynx	Binary	GWAS round 2: Results shared 1st August 2018. Imputed genotypes from HRC plus UK10K & 1000 Genomes reference panels as released by UK Biobank in March 2018.	MGI	Michigan Genomics Initiative	Fixed threshold (5e-05)	UKB GWAS (FINNGEN)	UKB_GWAS	https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761	65	0.092	0.000351515	0.0825		0.521	0.476-0.565	OR	4.7	1.91-11.5	4.7	1.91-11.5	3.41	1.65-7.07	3.41	1.65-7.07	1.78	0.968-3.26	1.78	0.968-3.26	1.41	0.866-2.28	1.41	0.866-2.28	1.24	0.867-1.79	1.24	0.867-1.79	0.658	0.404-1.07	0.0912	0.951	0.61-1.48	0.824	1.09	0.707-1.7	0.685	False	False	False	False	Both	158	1580	GRCh37/hg19	P<=5e-05					2020-06-08
prsweb-phecode149-4-c32-p-5e-05-mgi-20200608	prsweb-phecode149-4-c32-p-5e-05-mgi-20200608	PRSWEB_PHECODE149.4_C32_P_5e-05_MGI_20200608	P_5e-05	PRSWEB_PHECODE149.4_C32_P_5e-05_MGI_20200608	149.4	Diagnoses - main ICD10: C32 Malignant neoplasm of larynx	Binary	GWAS round 2: Results shared 1st August 2018. Imputed genotypes from HRC plus UK10K & 1000 Genomes reference panels as released by UK Biobank in March 2018.	MGI	Michigan Genomics Initiative	Fixed threshold (5e-05)	UKB GWAS (ICD10)	UKB_GWAS	https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761	56	0.65	0.000213295	0.0826		0.51	0.461-0.557	OR	3.39	1.24-9.26	3.39	1.24-9.26	1.7	0.67-4.3	1.7	0.67-4.3	1.48	0.777-2.81	1.48	0.777-2.81	1.41	0.87-2.28	1.41	0.87-2.28	0.959	0.657-1.4	0.959	0.657-1.4	0.953	0.593-1.53	0.841	1.27	0.813-1.99	0.293	1.03	0.647-1.65	0.893	False	False	False	False	Both	158	1580	GRCh37/hg19	P<=5e-05					2020-06-08
prsweb-phecode149-4-ukbb-saige-hrc-x149-4-p-5e-05-mgi-20200608	prsweb-phecode149-4-ukbb-saige-hrc-x149-4-p-5e-05-mgi-20200608	PRSWEB_PHECODE149.4_UKBB-SAIGE-HRC-X149.4_P_5e-05_MGI_20200608	P_5e-05	PRSWEB_PHECODE149.4_UKBB-SAIGE-HRC-X149.4_P_5e-05_MGI_20200608	149.4	Cancer of larynx	Binary	ICD9 and ICD10 based PheWAS codes	MGI	Michigan Genomics Initiative	Fixed threshold (5e-05)	UKB GWAS (PheCode)	UKB_GWAS	https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761	72	0.17	0.000522893	0.0826		0.53	0.484-0.577	OR	1.52	0.385-5.97	1.52	0.385-5.97	0.765	0.207-2.83	0.765	0.207-2.83	0.68	0.283-1.64	0.68	0.283-1.64	1.04	0.611-1.78	1.04	0.611-1.78	1.2	0.839-1.73	1.2	0.839-1.73	1.34	0.815-2.21	0.248	1.64	1.01-2.66	0.0451	1.63	1.01-2.65	0.0473	False	False	False	False	Both	158	1580	GRCh37/hg19	P<=5e-05					2020-06-08
prsweb-phecode149-4-20001-1006-p-5e-06-mgi-20200608	prsweb-phecode149-4-20001-1006-p-5e-06-mgi-20200608	PRSWEB_PHECODE149.4_20001-1006_P_5e-06_MGI_20200608	P_5e-06	PRSWEB_PHECODE149.4_20001-1006_P_5e-06_MGI_20200608	149.4	Cancer code, self-reported: larynx/throat cancer	Binary	GWAS round 2: Results shared 1st August 2018. Imputed genotypes from HRC plus UK10K & 1000 Genomes reference panels as released by UK Biobank in March 2018.	MGI	Michigan Genomics Initiative	Fixed threshold (5e-06)	UKB GWAS (PHESANT)	UKB_GWAS	https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761	11	0.78	0.00130816	0.0826		0.493	0.447-0.54	OR	2.12	0.645-6.97	2.12	0.645-6.97	1.07	0.349-3.3	1.07	0.349-3.3	0.934	0.434-2.01	0.934	0.434-2.01	0.97	0.562-1.68	0.97	0.562-1.68	1.02	0.704-1.49	1.02	0.704-1.49	1.12	0.715-1.76	0.616	0.978	0.614-1.56	0.926	1.05	0.663-1.66	0.835	False	False	False	False	Both	158	1580	GRCh37/hg19	P<=5e-06					2020-06-08
prsweb-phecode149-4-c3-larynx-p-5e-06-mgi-20200608	prsweb-phecode149-4-c3-larynx-p-5e-06-mgi-20200608	PRSWEB_PHECODE149.4_C3-LARYNX_P_5e-06_MGI_20200608	P_5e-06	PRSWEB_PHECODE149.4_C3-LARYNX_P_5e-06_MGI_20200608	149.4	Malignant neoplasm of larynx	Binary	GWAS round 2: Results shared 1st August 2018. Imputed genotypes from HRC plus UK10K & 1000 Genomes reference panels as released by UK Biobank in March 2018.	MGI	Michigan Genomics Initiative	Fixed threshold (5e-06)	UKB GWAS (FINNGEN)	UKB_GWAS	https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761	15	0.22	0.00315669	0.0826		0.517	0.468-0.567	OR	2.16	0.656-7.12	2.16	0.656-7.12	1.4	0.514-3.84	1.4	0.514-3.84	1.78	0.97-3.26	1.78	0.97-3.26	1.34	0.817-2.2	1.34	0.817-2.2	1.21	0.842-1.74	1.21	0.842-1.74	1.06	0.666-1.68	0.816	0.941	0.587-1.51	0.8	1.18	0.755-1.86	0.462	False	False	False	False	Both	158	1580	GRCh37/hg19	P<=5e-06					2020-06-08
prsweb-phecode149-4-c32-p-5e-06-mgi-20200608	prsweb-phecode149-4-c32-p-5e-06-mgi-20200608	PRSWEB_PHECODE149.4_C32_P_5e-06_MGI_20200608	P_5e-06	PRSWEB_PHECODE149.4_C32_P_5e-06_MGI_20200608	149.4	Diagnoses - main ICD10: C32 Malignant neoplasm of larynx	Binary	GWAS round 2: Results shared 1st August 2018. Imputed genotypes from HRC plus UK10K & 1000 Genomes reference panels as released by UK Biobank in March 2018.	MGI	Michigan Genomics Initiative	Fixed threshold (5e-06)	UKB GWAS (ICD10)	UKB_GWAS	https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761	15	0.77	8.9575e-05	0.0826		0.501	0.451-0.55	OR	2.12	0.642-7	2.12	0.642-7	1.38	0.503-3.77	1.38	0.503-3.77	0.934	0.435-2.01	0.934	0.435-2.01	1.04	0.61-1.77	1.04	0.61-1.77	1.13	0.783-1.63	1.13	0.783-1.63	0.809	0.501-1.31	0.385	1.13	0.726-1.77	0.58	1.09	0.695-1.71	0.71	False	False	False	False	Both	158	1580	GRCh37/hg19	P<=5e-06					2020-06-08
prsweb-phecode149-4-c32-pt-mgi-20200608	prsweb-phecode149-4-c32-pt-mgi-20200608	PRSWEB_PHECODE149.4_C32_PT_MGI_20200608	P&T	PRSWEB_PHECODE149.4_C32_PT_MGI_20200608	149.4	Diagnoses - main ICD10: C32 Malignant neoplasm of larynx	Binary	GWAS round 2: Results shared 1st August 2018. Imputed genotypes from HRC plus UK10K & 1000 Genomes reference panels as released by UK Biobank in March 2018.	MGI	Michigan Genomics Initiative	P&T	UKB GWAS (ICD10)	UKB_GWAS	https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761	106	0.44	0.00181696	0.0826		0.518	0.472-0.567	OR	2.16	0.642-7.25	2.16	0.642-7.25	1.39	0.504-3.86	1.39	0.504-3.86	1.48	0.778-2.82	1.48	0.778-2.82	0.906	0.516-1.59	0.906	0.516-1.59	1.2	0.838-1.72	1.2	0.838-1.72	0.962	0.599-1.55	0.874	1.12	0.704-1.77	0.638	1.24	0.792-1.96	0.343	False	False	False	False	Both	158	1580	GRCh37/hg19	P<=9.82e-05					2020-06-08
prsweb-phecode149-4-ukbb-saige-hrc-x149-4-pt-mgi-20200608	prsweb-phecode149-4-ukbb-saige-hrc-x149-4-pt-mgi-20200608	PRSWEB_PHECODE149.4_UKBB-SAIGE-HRC-X149.4_PT_MGI_20200608	P&T	PRSWEB_PHECODE149.4_UKBB-SAIGE-HRC-X149.4_PT_MGI_20200608	149.4	Cancer of larynx	Binary	ICD9 and ICD10 based PheWAS codes	MGI	Michigan Genomics Initiative	P&T	UKB GWAS (PheCode)	UKB_GWAS	https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761	53	0.025	0.00182003	0.0824		0.543	0.494-0.59	OR	1.52	0.384-5.98	1.52	0.384-5.98	0.764	0.207-2.82	0.764	0.207-2.82	1.47	0.776-2.8	1.47	0.776-2.8	1.11	0.66-1.87	1.11	0.66-1.87	1.36	0.953-1.93	1.36	0.953-1.93	1.48	0.902-2.44	0.12	1.5	0.909-2.47	0.113	1.78	1.1-2.88	0.019	True	False	False	True	Both	158	1580	GRCh37/hg19	P<=3.98e-05	https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000362/ScoringFiles/	https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000362/ScoringFiles/	/larsf/prsweb-data/cancerprsweb/releases/cancerprsweb_20200608/phewas/PRSWEB_PHECODE149.4_UKBB-SAIGE-HRC-X149.4_PT_MGI_20200608/all.tsv	/larsf/prsweb-data/cancerprsweb/releases/cancerprsweb_20200608/phewas/PRSWEB_PHECODE149.4_UKBB-SAIGE-HRC-X149.4_PT_MGI_20200608/exclusion.tsv	2020-06-08
prsweb-phecode149-4-c3-larynx-prs-cs-mgi-20200608	prsweb-phecode149-4-c3-larynx-prs-cs-mgi-20200608	PRSWEB_PHECODE149.4_C3-LARYNX_PRS-CS_MGI_20200608	PRS-CS	PRSWEB_PHECODE149.4_C3-LARYNX_PRS-CS_MGI_20200608	149.4	Malignant neoplasm of larynx	Binary	GWAS round 2: Results shared 1st August 2018. Imputed genotypes from HRC plus UK10K & 1000 Genomes reference panels as released by UK Biobank in March 2018.	MGI	Michigan Genomics Initiative	PRS-CS	UKB GWAS (FINNGEN)	UKB_GWAS	https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761	978910	0.44	0.000973724	0.0826		0.526	0.479-0.571	OR	0	0-0	0	0-0	1.07	0.348-3.29	1.07	0.348-3.29	0.935	0.435-2.01	0.935	0.435-2.01	0.899	0.513-1.58	0.899	0.513-1.58	1.06	0.731-1.53	1.06	0.731-1.53	0.937	0.572-1.54	0.798	1.51	0.962-2.37	0.0729	1.26	0.788-2.02	0.334	False	False	False	False	Both	158	1580	GRCh37/hg19	auto					2020-06-08
prsweb-phecode149-4-c32-prs-cs-mgi-20200608	prsweb-phecode149-4-c32-prs-cs-mgi-20200608	PRSWEB_PHECODE149.4_C32_PRS-CS_MGI_20200608	PRS-CS	PRSWEB_PHECODE149.4_C32_PRS-CS_MGI_20200608	149.4	Diagnoses - main ICD10: C32 Malignant neoplasm of larynx	Binary	GWAS round 2: Results shared 1st August 2018. Imputed genotypes from HRC plus UK10K & 1000 Genomes reference panels as released by UK Biobank in March 2018.	MGI	Michigan Genomics Initiative	PRS-CS	UKB GWAS (ICD10)	UKB_GWAS	https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761	967720	0.19	0.000580688	0.0826		0.532	0.487-0.58	OR	0.905	0.162-5.05	0.905	0.162-5.05	0.455	0.0867-2.39	0.455	0.0867-2.39	1.2	0.599-2.39	1.2	0.599-2.39	0.966	0.559-1.67	0.966	0.559-1.67	1.13	0.781-1.62	1.13	0.781-1.62	1.36	0.84-2.2	0.211	1.43	0.888-2.3	0.141	1.38	0.861-2.22	0.181	False	False	False	False	Both	158	1580	GRCh37/hg19	auto					2020-06-08
prsweb-phecode149-4-ukbb-saige-hrc-x149-4-prs-cs-mgi-20200608	prsweb-phecode149-4-ukbb-saige-hrc-x149-4-prs-cs-mgi-20200608	PRSWEB_PHECODE149.4_UKBB-SAIGE-HRC-X149.4_PRS-CS_MGI_20200608	PRS-CS	PRSWEB_PHECODE149.4_UKBB-SAIGE-HRC-X149.4_PRS-CS_MGI_20200608	149.4	Cancer of larynx	Binary	ICD9 and ICD10 based PheWAS codes	MGI	Michigan Genomics Initiative	PRS-CS	UKB GWAS (PheCode)	UKB_GWAS	https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761	1119238	0.73	0.000161474	0.0826		0.508	0.464-0.556	OR	0	0-0	0	0-0	0.454	0.087-2.37	0.454	0.087-2.37	1.07	0.518-2.21	1.07	0.518-2.21	1.19	0.712-1.98	1.19	0.712-1.98	0.96	0.656-1.4	0.96	0.656-1.4	1.18	0.745-1.86	0.486	1.09	0.686-1.73	0.719	1.11	0.694-1.78	0.66	False	False	False	False	Both	158	1580	GRCh37/hg19	auto					2020-06-08
prsweb-phecode149-4-c3-larynx-lassosum-mgi-20200608	prsweb-phecode149-4-c3-larynx-lassosum-mgi-20200608	PRSWEB_PHECODE149.4_C3-LARYNX_LASSOSUM_MGI_20200608	Lassosum	PRSWEB_PHECODE149.4_C3-LARYNX_LASSOSUM_MGI_20200608	149.4	Malignant neoplasm of larynx	Binary	GWAS round 2: Results shared 1st August 2018. Imputed genotypes from HRC plus UK10K & 1000 Genomes reference panels as released by UK Biobank in March 2018.	MGI	Michigan Genomics Initiative	lassosum	UKB GWAS (FINNGEN)	UKB_GWAS	https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761	87893	0.033	0.00197245	0.0824		0.55	0.504-0.593	OR	1.51	0.382-5.94	1.51	0.382-5.94	1.71	0.675-4.32	1.71	0.675-4.32	1.47	0.777-2.8	1.47	0.777-2.8	1.18	0.709-1.97	1.18	0.709-1.97	1.32	0.924-1.88	1.32	0.924-1.88	1.92	1.15-3.22	0.0128	1.82	1.08-3.06	0.0245	2.2	1.32-3.67	0.00236	True	False	False	True	Both	158	1580	GRCh37/hg19	s=1;Lambda=0.07848	https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000361/ScoringFiles/	https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000361/ScoringFiles/	/larsf/prsweb-data/cancerprsweb/releases/cancerprsweb_20200608/phewas/PRSWEB_PHECODE149.4_C3-LARYNX_LASSOSUM_MGI_20200608/all.tsv	/larsf/prsweb-data/cancerprsweb/releases/cancerprsweb_20200608/phewas/PRSWEB_PHECODE149.4_C3-LARYNX_LASSOSUM_MGI_20200608/exclusion.tsv	2020-06-08
prsweb-phecode149-4-c32-lassosum-mgi-20200608	prsweb-phecode149-4-c32-lassosum-mgi-20200608	PRSWEB_PHECODE149.4_C32_LASSOSUM_MGI_20200608	Lassosum	PRSWEB_PHECODE149.4_C32_LASSOSUM_MGI_20200608	149.4	Diagnoses - main ICD10: C32 Malignant neoplasm of larynx	Binary	GWAS round 2: Results shared 1st August 2018. Imputed genotypes from HRC plus UK10K & 1000 Genomes reference panels as released by UK Biobank in March 2018.	MGI	Michigan Genomics Initiative	lassosum	UKB GWAS (ICD10)	UKB_GWAS	https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761	25920	0.0027	0.00677471	0.0822		0.57	0.522-0.618	OR	2.14	0.649-7.06	2.14	0.649-7.06	2.36	1.04-5.35	2.36	1.04-5.35	1.75	0.958-3.19	1.75	0.958-3.19	1.4	0.864-2.27	1.4	0.864-2.27	1.61	1.14-2.27	1.61	1.14-2.27	1.25	0.745-2.11	0.393	1.72	1.05-2.83	0.0323	2.09	1.29-3.39	0.00264	True	False	False	True	Both	158	1580	GRCh37/hg19	s=0.9;Lambda=0.1	https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000360/ScoringFiles/	https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000360/ScoringFiles/	/larsf/prsweb-data/cancerprsweb/releases/cancerprsweb_20200608/phewas/PRSWEB_PHECODE149.4_C32_LASSOSUM_MGI_20200608/all.tsv	/larsf/prsweb-data/cancerprsweb/releases/cancerprsweb_20200608/phewas/PRSWEB_PHECODE149.4_C32_LASSOSUM_MGI_20200608/exclusion.tsv	2020-06-08
prsweb-phecode149-4-ukbb-saige-hrc-x149-4-lassosum-mgi-20200608	prsweb-phecode149-4-ukbb-saige-hrc-x149-4-lassosum-mgi-20200608	PRSWEB_PHECODE149.4_UKBB-SAIGE-HRC-X149.4_LASSOSUM_MGI_20200608	Lassosum	PRSWEB_PHECODE149.4_UKBB-SAIGE-HRC-X149.4_LASSOSUM_MGI_20200608	149.4	Cancer of larynx	Binary	ICD9 and ICD10 based PheWAS codes	MGI	Michigan Genomics Initiative	lassosum	UKB GWAS (PheCode)	UKB_GWAS	https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761	175596	0.11	0.0027602	0.0825		0.534	0.486-0.578	OR	2.14	0.649-7.03	2.14	0.649-7.03	2.7	1.24-5.92	2.7	1.24-5.92	1.9	1.06-3.42	1.9	1.06-3.42	1.41	0.868-2.28	1.41	0.868-2.28	1.4	0.984-1.99	1.4	0.984-1.99	1.07	0.67-1.7	0.786	0.82	0.501-1.34	0.43	1.32	0.844-2.06	0.224	False	False	False	False	Both	158	1580	GRCh37/hg19	s=0.9;Lambda=0.06158					2020-06-08