prs_id slug legacy_id legacy_model prswebprefix trait_code trait_name trait_type description cohort cohort_label method gwas_source reference_label reference_url snp_count p_value pseudo_r2 brier_score mse aauc aauc_ci effect_metric top_effect_1 top_effect_1_ci top_or_1 top_or_1_ci top_effect_2 top_effect_2_ci top_or_2 top_or_2_ci top_effect_5 top_effect_5_ci top_or_5 top_or_5_ci top_effect_10 top_effect_10_ci top_or_10 top_or_10_ci top_effect_25 top_effect_25_ci top_or_25 top_or_25_ci q1_vs_q2_effect q1_vs_q2_effect_ci q1_vs_q2_p_value q1_vs_q3_effect q1_vs_q3_effect_ci q1_vs_q3_p_value q1_vs_q4_effect q1_vs_q4_effect_ci q1_vs_q4_p_value nominally_significant reversed_effect_warning underpowered_warning upload_to_portal sex cases controls genome_build tuning_parameter weights_external_url weights_url phewas_download_url exclusion_download_url last_updated prsweb-phecode150-20001-1017-p-5e-05-mgi-20200608 prsweb-phecode150-20001-1017-p-5e-05-mgi-20200608 PRSWEB_PHECODE150_20001-1017_P_5e-05_MGI_20200608 P_5e-05 PRSWEB_PHECODE150_20001-1017_P_5e-05_MGI_20200608 150 Cancer code, self-reported: oesophageal cancer Binary GWAS round 2: Results shared 1st August 2018. Imputed genotypes from HRC plus UK10K & 1000 Genomes reference panels as released by UK Biobank in March 2018. MGI Michigan Genomics Initiative Fixed threshold (5e-05) UKB GWAS (PHESANT) UKB_GWAS https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761 60 0.89 0.00112702 0.0828 0.502 0.46-0.543 OR 0 0-0 0 0-0 0.908 0.299-2.76 0.908 0.299-2.76 1.45 0.802-2.62 1.45 0.802-2.62 1.09 0.672-1.76 1.09 0.672-1.76 1.04 0.737-1.46 1.04 0.737-1.46 1.4 0.927-2.12 0.109 0.974 0.624-1.52 0.908 1.14 0.74-1.74 0.561 False False False False Both 188 1876 GRCh37/hg19 P<=5e-05 2020-06-08 prsweb-phecode150-c15-p-5e-05-mgi-20200608 prsweb-phecode150-c15-p-5e-05-mgi-20200608 PRSWEB_PHECODE150_C15_P_5e-05_MGI_20200608 P_5e-05 PRSWEB_PHECODE150_C15_P_5e-05_MGI_20200608 150 Diagnoses - main ICD10: C15 Malignant neoplasm of oesophagus Binary GWAS round 2: Results shared 1st August 2018. Imputed genotypes from HRC plus UK10K & 1000 Genomes reference panels as released by UK Biobank in March 2018. MGI Michigan Genomics Initiative Fixed threshold (5e-05) UKB GWAS (ICD10) UKB_GWAS https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761 109 0.0047 0.00187595 0.0825 0.555 0.514-0.596 OR 2.3 0.798-6.63 2.3 0.798-6.63 2.22 1.03-4.79 2.22 1.03-4.79 1.56 0.876-2.77 1.56 0.876-2.77 1.33 0.85-2.09 1.33 0.85-2.09 1.41 1.02-1.95 1.41 1.02-1.95 1.35 0.851-2.14 0.203 1.53 0.976-2.39 0.064 1.76 1.14-2.73 0.0112 True False False False Both 188 1876 GRCh37/hg19 P<=5e-05 2020-06-08 prsweb-phecode150-c3-oesophagus-p-5e-05-mgi-20200608 prsweb-phecode150-c3-oesophagus-p-5e-05-mgi-20200608 PRSWEB_PHECODE150_C3-OESOPHAGUS_P_5e-05_MGI_20200608 P_5e-05 PRSWEB_PHECODE150_C3-OESOPHAGUS_P_5e-05_MGI_20200608 150 Malignant neoplasm of oesophagus Binary GWAS round 2: Results shared 1st August 2018. Imputed genotypes from HRC plus UK10K & 1000 Genomes reference panels as released by UK Biobank in March 2018. MGI Michigan Genomics Initiative Fixed threshold (5e-05) UKB GWAS (FINNGEN) UKB_GWAS https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761 96 0.26 3.52269e-05 0.0827 0.529 0.483-0.568 OR 1.28 0.331-4.96 1.28 0.331-4.96 0.903 0.296-2.75 0.903 0.296-2.75 1 0.505-1.99 1 0.505-1.99 1.1 0.677-1.78 1.1 0.677-1.78 1.22 0.874-1.7 1.22 0.874-1.7 1.05 0.681-1.63 0.817 1.13 0.737-1.73 0.575 1.28 0.842-1.94 0.249 False False False False Both 188 1876 GRCh37/hg19 P<=5e-05 2020-06-08 prsweb-phecode150-gwas-catalog-r2019-05-03-x150-p-5e-05-mgi-20200608 prsweb-phecode150-gwas-catalog-r2019-05-03-x150-p-5e-05-mgi-20200608 PRSWEB_PHECODE150_GWAS-Catalog-r2019-05-03-X150_P_5e-05_MGI_20200608 P_5e-05 PRSWEB_PHECODE150_GWAS-Catalog-r2019-05-03-X150_P_5e-05_MGI_20200608 150 Esophageal adenocarcinoma Binary 8 unique SNPs MGI Michigan Genomics Initiative Fixed threshold (5e-05) GWAS Catalog (2019-05-03) 24121790 https://www.ncbi.nlm.nih.gov/pubmed/?term=24121790 7 0.71 0.000294309 0.0828 0.517 0.476-0.562 OR 0.769 0.14-4.21 0.769 0.14-4.21 0.907 0.298-2.76 0.907 0.298-2.76 1.69 0.962-2.95 1.69 0.962-2.95 1.52 0.989-2.34 1.52 0.989-2.34 1.21 0.872-1.69 1.21 0.872-1.69 0.982 0.64-1.51 0.933 0.983 0.641-1.51 0.939 1.24 0.819-1.87 0.31 False False False False Both 188 1876 GRCh37/hg19 P<=5e-05 2020-06-08 prsweb-phecode150-ukbb-saige-hrc-x150-p-5e-05-mgi-20200608 prsweb-phecode150-ukbb-saige-hrc-x150-p-5e-05-mgi-20200608 PRSWEB_PHECODE150_UKBB-SAIGE-HRC-X150_P_5e-05_MGI_20200608 P_5e-05 PRSWEB_PHECODE150_UKBB-SAIGE-HRC-X150_P_5e-05_MGI_20200608 150 Cancer of esophagus Binary ICD9 and ICD10 based PheWAS codes MGI Michigan Genomics Initiative Fixed threshold (5e-05) UKB GWAS (PheCode) UKB_GWAS https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761 105 0.51 0.000256789 0.0828 0.51 0.472-0.555 OR 1.27 0.328-4.89 1.27 0.328-4.89 1.15 0.426-3.13 1.15 0.426-3.13 1.44 0.798-2.6 1.44 0.798-2.6 0.964 0.584-1.59 0.964 0.584-1.59 1.06 0.754-1.49 1.06 0.754-1.49 0.963 0.622-1.49 0.866 1.24 0.818-1.88 0.31 1.14 0.741-1.74 0.558 False False False False Both 188 1876 GRCh37/hg19 P<=5e-05 2020-06-08 prsweb-phecode150-20001-1017-p-5e-06-mgi-20200608 prsweb-phecode150-20001-1017-p-5e-06-mgi-20200608 PRSWEB_PHECODE150_20001-1017_P_5e-06_MGI_20200608 P_5e-06 PRSWEB_PHECODE150_20001-1017_P_5e-06_MGI_20200608 150 Cancer code, self-reported: oesophageal cancer Binary GWAS round 2: Results shared 1st August 2018. Imputed genotypes from HRC plus UK10K & 1000 Genomes reference panels as released by UK Biobank in March 2018. MGI Michigan Genomics Initiative Fixed threshold (5e-06) UKB GWAS (PHESANT) UKB_GWAS https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761 10 0.17 0.00317397 0.0827 0.52 0.478-0.565 OR 0.764 0.14-4.16 0.764 0.14-4.16 1.16 0.431-3.14 1.16 0.431-3.14 1.1 0.573-2.13 1.1 0.573-2.13 1.03 0.629-1.68 1.03 0.629-1.68 1.09 0.781-1.53 1.09 0.781-1.53 1.2 0.777-1.86 0.408 1.33 0.866-2.04 0.193 1.27 0.828-1.96 0.27 False False False False Both 188 1876 GRCh37/hg19 P<=5e-06 2020-06-08 prsweb-phecode150-c15-p-5e-06-mgi-20200608 prsweb-phecode150-c15-p-5e-06-mgi-20200608 PRSWEB_PHECODE150_C15_P_5e-06_MGI_20200608 P_5e-06 PRSWEB_PHECODE150_C15_P_5e-06_MGI_20200608 150 Diagnoses - main ICD10: C15 Malignant neoplasm of oesophagus Binary GWAS round 2: Results shared 1st August 2018. Imputed genotypes from HRC plus UK10K & 1000 Genomes reference panels as released by UK Biobank in March 2018. MGI Michigan Genomics Initiative Fixed threshold (5e-06) UKB GWAS (ICD10) UKB_GWAS https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761 25 0.53 0.00122208 0.0828 0.51 0.462-0.551 OR 0 0-0 0 0-0 0.911 0.299-2.77 0.911 0.299-2.77 0.78 0.366-1.67 0.78 0.366-1.67 1.15 0.718-1.85 1.15 0.718-1.85 1.06 0.757-1.49 1.06 0.757-1.49 1.26 0.822-1.93 0.289 1.15 0.747-1.77 0.524 1.18 0.771-1.82 0.439 False False False False Both 188 1876 GRCh37/hg19 P<=5e-06 2020-06-08 prsweb-phecode150-gwas-catalog-r2019-05-03-x150-p-5e-06-mgi-20200608 prsweb-phecode150-gwas-catalog-r2019-05-03-x150-p-5e-06-mgi-20200608 PRSWEB_PHECODE150_GWAS-Catalog-r2019-05-03-X150_P_5e-06_MGI_20200608 P_5e-06 PRSWEB_PHECODE150_GWAS-Catalog-r2019-05-03-X150_P_5e-06_MGI_20200608 150 Esophageal adenocarcinoma Binary 8 unique SNPs MGI Michigan Genomics Initiative Fixed threshold (5e-06) GWAS Catalog (2019-05-03) 24121790 https://www.ncbi.nlm.nih.gov/pubmed/?term=24121790 7 0.71 0.000294309 0.0828 0.517 0.476-0.562 OR 0.769 0.14-4.21 0.769 0.14-4.21 0.907 0.298-2.76 0.907 0.298-2.76 1.69 0.962-2.95 1.69 0.962-2.95 1.52 0.989-2.34 1.52 0.989-2.34 1.21 0.872-1.69 1.21 0.872-1.69 0.982 0.64-1.51 0.933 0.983 0.641-1.51 0.939 1.24 0.819-1.87 0.31 False False False False Both 188 1876 GRCh37/hg19 P<=5e-06 2020-06-08 prsweb-phecode150-ukbb-saige-hrc-x150-p-5e-06-mgi-20200608 prsweb-phecode150-ukbb-saige-hrc-x150-p-5e-06-mgi-20200608 PRSWEB_PHECODE150_UKBB-SAIGE-HRC-X150_P_5e-06_MGI_20200608 P_5e-06 PRSWEB_PHECODE150_UKBB-SAIGE-HRC-X150_P_5e-06_MGI_20200608 150 Cancer of esophagus Binary ICD9 and ICD10 based PheWAS codes MGI Michigan Genomics Initiative Fixed threshold (5e-06) UKB GWAS (PheCode) UKB_GWAS https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761 7 0.75 0.000160455 0.0828 0.462 0.425-0.502 OR 1.79 0.556-5.78 1.79 0.556-5.78 1.43 0.574-3.57 1.43 0.574-3.57 1.57 0.885-2.79 1.57 0.885-2.79 1.09 0.674-1.76 1.09 0.674-1.76 0.924 0.651-1.31 0.924 0.651-1.31 0.817 0.536-1.25 0.349 0.911 0.598-1.39 0.663 0.826 0.54-1.26 0.377 False False False False Both 188 1876 GRCh37/hg19 P<=5e-06 2020-06-08 prsweb-phecode150-20001-1017-pt-mgi-20200608 prsweb-phecode150-20001-1017-pt-mgi-20200608 PRSWEB_PHECODE150_20001-1017_PT_MGI_20200608 P&T PRSWEB_PHECODE150_20001-1017_PT_MGI_20200608 150 Cancer code, self-reported: oesophageal cancer Binary GWAS round 2: Results shared 1st August 2018. Imputed genotypes from HRC plus UK10K & 1000 Genomes reference panels as released by UK Biobank in March 2018. MGI Michigan Genomics Initiative P&T UKB GWAS (PHESANT) UKB_GWAS https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761 24 0.2 0.00593107 0.0827 0.519 0.479-0.559 OR 1.78 0.551-5.73 1.78 0.551-5.73 1.16 0.428-3.13 1.16 0.428-3.13 0.993 0.501-1.97 0.993 0.501-1.97 1.03 0.627-1.68 1.03 0.627-1.68 1.12 0.802-1.57 1.12 0.802-1.57 1.44 0.928-2.22 0.104 1.34 0.862-2.09 0.191 1.4 0.902-2.17 0.134 False False False False Both 188 1876 GRCh37/hg19 P<=1.58e-05 2020-06-08 prsweb-phecode150-c15-pt-mgi-20200608 prsweb-phecode150-c15-pt-mgi-20200608 PRSWEB_PHECODE150_C15_PT_MGI_20200608 P&T PRSWEB_PHECODE150_C15_PT_MGI_20200608 150 Diagnoses - main ICD10: C15 Malignant neoplasm of oesophagus Binary GWAS round 2: Results shared 1st August 2018. Imputed genotypes from HRC plus UK10K & 1000 Genomes reference panels as released by UK Biobank in March 2018. MGI Michigan Genomics Initiative P&T UKB GWAS (ICD10) UKB_GWAS https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761 62 0.15 0.00286636 0.0827 0.532 0.486-0.57 OR 1.27 0.329-4.91 1.27 0.329-4.91 0.638 0.175-2.33 0.638 0.175-2.33 0.89 0.434-1.82 0.89 0.434-1.82 1.03 0.63-1.68 1.03 0.63-1.68 1.28 0.923-1.78 1.28 0.923-1.78 1.12 0.715-1.74 0.629 1.24 0.804-1.91 0.331 1.44 0.937-2.2 0.0964 False False False False Both 188 1876 GRCh37/hg19 P<=2.51e-05 2020-06-08 prsweb-phecode150-c3-oesophagus-pt-mgi-20200608 prsweb-phecode150-c3-oesophagus-pt-mgi-20200608 PRSWEB_PHECODE150_C3-OESOPHAGUS_PT_MGI_20200608 P&T PRSWEB_PHECODE150_C3-OESOPHAGUS_PT_MGI_20200608 150 Malignant neoplasm of oesophagus Binary GWAS round 2: Results shared 1st August 2018. Imputed genotypes from HRC plus UK10K & 1000 Genomes reference panels as released by UK Biobank in March 2018. MGI Michigan Genomics Initiative P&T UKB GWAS (FINNGEN) UKB_GWAS https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761 143 0.094 0.00186688 0.0827 0.538 0.492-0.577 OR 0 0-0 0 0-0 1.18 0.435-3.18 1.18 0.435-3.18 0.673 0.3-1.51 0.673 0.3-1.51 1.09 0.675-1.77 1.09 0.675-1.77 1.38 0.998-1.9 1.38 0.998-1.9 0.821 0.524-1.29 0.39 1.08 0.705-1.64 0.733 1.35 0.898-2.02 0.149 False False False False Both 188 1876 GRCh37/hg19 P<=7.94e-05 2020-06-08 prsweb-phecode150-gwas-catalog-r2019-05-03-x150-pt-mgi-20200608 prsweb-phecode150-gwas-catalog-r2019-05-03-x150-pt-mgi-20200608 PRSWEB_PHECODE150_GWAS-Catalog-r2019-05-03-X150_PT_MGI_20200608 P&T PRSWEB_PHECODE150_GWAS-Catalog-r2019-05-03-X150_PT_MGI_20200608 150 Esophageal adenocarcinoma Binary 8 unique SNPs MGI Michigan Genomics Initiative P&T GWAS Catalog (2019-05-03) 24121790 https://www.ncbi.nlm.nih.gov/pubmed/?term=24121790 7 0.71 0.000294309 0.0828 0.517 0.476-0.562 OR 0.769 0.14-4.21 0.769 0.14-4.21 0.907 0.298-2.76 0.907 0.298-2.76 1.69 0.962-2.95 1.69 0.962-2.95 1.52 0.989-2.34 1.52 0.989-2.34 1.21 0.872-1.69 1.21 0.872-1.69 0.982 0.64-1.51 0.933 0.983 0.641-1.51 0.939 1.24 0.819-1.87 0.31 False False False False Both 188 1876 GRCh37/hg19 P<=5e-06 2020-06-08 prsweb-phecode150-ukbb-saige-hrc-x150-pt-mgi-20200608 prsweb-phecode150-ukbb-saige-hrc-x150-pt-mgi-20200608 PRSWEB_PHECODE150_UKBB-SAIGE-HRC-X150_PT_MGI_20200608 P&T PRSWEB_PHECODE150_UKBB-SAIGE-HRC-X150_PT_MGI_20200608 150 Cancer of esophagus Binary ICD9 and ICD10 based PheWAS codes MGI Michigan Genomics Initiative P&T UKB GWAS (PheCode) UKB_GWAS https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761 45 0.8 0.00215333 0.0828 0.504 0.465-0.548 OR 1.27 0.329-4.92 1.27 0.329-4.92 0.898 0.295-2.73 0.898 0.295-2.73 1.11 0.574-2.13 1.11 0.574-2.13 1.09 0.671-1.76 1.09 0.671-1.76 1 0.711-1.41 1 0.711-1.41 0.987 0.64-1.52 0.954 1.19 0.788-1.8 0.405 1.06 0.695-1.63 0.773 False False False False Both 188 1876 GRCh37/hg19 P<=2.51e-05 2020-06-08 prsweb-phecode150-20001-1017-prs-cs-mgi-20200608 prsweb-phecode150-20001-1017-prs-cs-mgi-20200608 PRSWEB_PHECODE150_20001-1017_PRS-CS_MGI_20200608 PRS-CS PRSWEB_PHECODE150_20001-1017_PRS-CS_MGI_20200608 150 Cancer code, self-reported: oesophageal cancer Binary GWAS round 2: Results shared 1st August 2018. Imputed genotypes from HRC plus UK10K & 1000 Genomes reference panels as released by UK Biobank in March 2018. MGI Michigan Genomics Initiative PRS-CS UKB GWAS (PHESANT) UKB_GWAS https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761 934591 0.068 0.000755737 0.0827 0.535 0.493-0.579 OR 1.79 0.556-5.77 1.79 0.556-5.77 1.42 0.572-3.55 1.42 0.572-3.55 1.22 0.65-2.3 1.22 0.65-2.3 1.15 0.716-1.84 1.15 0.716-1.84 1.04 0.737-1.46 1.04 0.737-1.46 1.76 1.12-2.76 0.0136 1.7 1.08-2.67 0.0221 1.56 0.985-2.48 0.0582 False False False False Both 188 1876 GRCh37/hg19 auto 2020-06-08 prsweb-phecode150-c15-prs-cs-mgi-20200608 prsweb-phecode150-c15-prs-cs-mgi-20200608 PRSWEB_PHECODE150_C15_PRS-CS_MGI_20200608 PRS-CS PRSWEB_PHECODE150_C15_PRS-CS_MGI_20200608 150 Diagnoses - main ICD10: C15 Malignant neoplasm of oesophagus Binary GWAS round 2: Results shared 1st August 2018. Imputed genotypes from HRC plus UK10K & 1000 Genomes reference panels as released by UK Biobank in March 2018. MGI Michigan Genomics Initiative PRS-CS UKB GWAS (ICD10) UKB_GWAS https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761 1081646 0.0036 0.00344085 0.0825 0.564 0.525-0.604 OR 2.84 1.07-7.54 2.84 1.07-7.54 1.7 0.727-3.99 1.7 0.727-3.99 1.22 0.651-2.3 1.22 0.651-2.3 1.34 0.853-2.09 1.34 0.853-2.09 1.38 0.998-1.91 1.38 0.998-1.91 1.98 1.23-3.2 0.00501 1.98 1.22-3.21 0.00543 2.19 1.36-3.5 0.00113 True False False True Both 188 1876 GRCh37/hg19 auto https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000363/ScoringFiles/ https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000363/ScoringFiles/ /larsf/prsweb-data/cancerprsweb/releases/cancerprsweb_20200608/phewas/PRSWEB_PHECODE150_C15_PRS-CS_MGI_20200608/all.tsv /larsf/prsweb-data/cancerprsweb/releases/cancerprsweb_20200608/phewas/PRSWEB_PHECODE150_C15_PRS-CS_MGI_20200608/exclusion.tsv 2020-06-08 prsweb-phecode150-c3-oesophagus-prs-cs-mgi-20200608 prsweb-phecode150-c3-oesophagus-prs-cs-mgi-20200608 PRSWEB_PHECODE150_C3-OESOPHAGUS_PRS-CS_MGI_20200608 PRS-CS PRSWEB_PHECODE150_C3-OESOPHAGUS_PRS-CS_MGI_20200608 150 Malignant neoplasm of oesophagus Binary GWAS round 2: Results shared 1st August 2018. Imputed genotypes from HRC plus UK10K & 1000 Genomes reference panels as released by UK Biobank in March 2018. MGI Michigan Genomics Initiative PRS-CS UKB GWAS (FINNGEN) UKB_GWAS https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761 1070434 0.026 0.0039263 0.0826 0.553 0.514-0.596 OR 1.27 0.329-4.9 1.27 0.329-4.9 1.17 0.433-3.17 1.17 0.433-3.17 0.999 0.503-1.99 0.999 0.503-1.99 1.33 0.851-2.09 1.33 0.851-2.09 1.12 0.803-1.57 1.12 0.803-1.57 1.23 0.78-1.94 0.374 1.65 1.07-2.54 0.023 1.43 0.919-2.22 0.113 True False False True Both 188 1876 GRCh37/hg19 auto https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000365/ScoringFiles/ https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000365/ScoringFiles/ /larsf/prsweb-data/cancerprsweb/releases/cancerprsweb_20200608/phewas/PRSWEB_PHECODE150_C3-OESOPHAGUS_PRS-CS_MGI_20200608/all.tsv /larsf/prsweb-data/cancerprsweb/releases/cancerprsweb_20200608/phewas/PRSWEB_PHECODE150_C3-OESOPHAGUS_PRS-CS_MGI_20200608/exclusion.tsv 2020-06-08 prsweb-phecode150-ukbb-saige-hrc-x150-prs-cs-mgi-20200608 prsweb-phecode150-ukbb-saige-hrc-x150-prs-cs-mgi-20200608 PRSWEB_PHECODE150_UKBB-SAIGE-HRC-X150_PRS-CS_MGI_20200608 PRS-CS PRSWEB_PHECODE150_UKBB-SAIGE-HRC-X150_PRS-CS_MGI_20200608 150 Cancer of esophagus Binary ICD9 and ICD10 based PheWAS codes MGI Michigan Genomics Initiative PRS-CS UKB GWAS (PheCode) UKB_GWAS https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761 1119238 0.005 0.000445815 0.0825 0.564 0.522-0.605 OR 1.28 0.332-4.95 1.28 0.332-4.95 1.44 0.577-3.58 1.44 0.577-3.58 1.45 0.803-2.63 1.45 0.803-2.63 1.27 0.802-2 1.27 0.802-2 1.41 1.02-1.94 1.41 1.02-1.94 1.43 0.905-2.28 0.125 1.51 0.956-2.37 0.0772 1.85 1.19-2.87 0.00643 True False False True Both 188 1876 GRCh37/hg19 auto https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000366/ScoringFiles/ https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000366/ScoringFiles/ /larsf/prsweb-data/cancerprsweb/releases/cancerprsweb_20200608/phewas/PRSWEB_PHECODE150_UKBB-SAIGE-HRC-X150_PRS-CS_MGI_20200608/all.tsv /larsf/prsweb-data/cancerprsweb/releases/cancerprsweb_20200608/phewas/PRSWEB_PHECODE150_UKBB-SAIGE-HRC-X150_PRS-CS_MGI_20200608/exclusion.tsv 2020-06-08 prsweb-phecode150-20001-1017-lassosum-mgi-20200608 prsweb-phecode150-20001-1017-lassosum-mgi-20200608 PRSWEB_PHECODE150_20001-1017_LASSOSUM_MGI_20200608 Lassosum PRSWEB_PHECODE150_20001-1017_LASSOSUM_MGI_20200608 150 Cancer code, self-reported: oesophageal cancer Binary GWAS round 2: Results shared 1st August 2018. Imputed genotypes from HRC plus UK10K & 1000 Genomes reference panels as released by UK Biobank in March 2018. MGI Michigan Genomics Initiative lassosum UKB GWAS (PHESANT) UKB_GWAS https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761 406747 0.28 0.00375339 0.0827 0.519 0.478-0.563 OR 1.79 0.557-5.78 1.79 0.557-5.78 1.42 0.571-3.55 1.42 0.571-3.55 1.22 0.649-2.29 1.22 0.649-2.29 1.03 0.63-1.68 1.03 0.63-1.68 1.01 0.714-1.42 1.01 0.714-1.42 1.24 0.801-1.93 0.331 1.47 0.956-2.25 0.0796 1.23 0.791-1.91 0.36 False False False False Both 188 1876 GRCh37/hg19 s=1;Lambda=0.06158 2020-06-08 prsweb-phecode150-c15-lassosum-mgi-20200608 prsweb-phecode150-c15-lassosum-mgi-20200608 PRSWEB_PHECODE150_C15_LASSOSUM_MGI_20200608 Lassosum PRSWEB_PHECODE150_C15_LASSOSUM_MGI_20200608 150 Diagnoses - main ICD10: C15 Malignant neoplasm of oesophagus Binary GWAS round 2: Results shared 1st August 2018. Imputed genotypes from HRC plus UK10K & 1000 Genomes reference panels as released by UK Biobank in March 2018. MGI Michigan Genomics Initiative lassosum UKB GWAS (ICD10) UKB_GWAS https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761 2001 0.012 0.00421728 0.0826 0.551 0.51-0.588 OR 1.81 0.56-5.82 1.81 0.56-5.82 1.44 0.576-3.58 1.44 0.576-3.58 1.22 0.652-2.3 1.22 0.652-2.3 1.47 0.946-2.27 1.47 0.946-2.27 1.6 1.16-2.19 1.6 1.16-2.19 1.53 0.989-2.38 0.0563 1.01 0.627-1.62 0.969 1.83 1.2-2.81 0.00549 True False False True Both 188 1876 GRCh37/hg19 s=1;Lambda=0.07848 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000364/ScoringFiles/ https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000364/ScoringFiles/ /larsf/prsweb-data/cancerprsweb/releases/cancerprsweb_20200608/phewas/PRSWEB_PHECODE150_C15_LASSOSUM_MGI_20200608/all.tsv /larsf/prsweb-data/cancerprsweb/releases/cancerprsweb_20200608/phewas/PRSWEB_PHECODE150_C15_LASSOSUM_MGI_20200608/exclusion.tsv 2020-06-08 prsweb-phecode150-c3-oesophagus-lassosum-mgi-20200608 prsweb-phecode150-c3-oesophagus-lassosum-mgi-20200608 PRSWEB_PHECODE150_C3-OESOPHAGUS_LASSOSUM_MGI_20200608 Lassosum PRSWEB_PHECODE150_C3-OESOPHAGUS_LASSOSUM_MGI_20200608 150 Malignant neoplasm of oesophagus Binary GWAS round 2: Results shared 1st August 2018. Imputed genotypes from HRC plus UK10K & 1000 Genomes reference panels as released by UK Biobank in March 2018. MGI Michigan Genomics Initiative lassosum UKB GWAS (FINNGEN) UKB_GWAS https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761 91277 0.24 0.00646968 0.0827 0.531 0.494-0.57 OR 0 0-0 0 0-0 0.641 0.175-2.35 0.641 0.175-2.35 0.566 0.237-1.35 0.566 0.237-1.35 0.798 0.466-1.37 0.798 0.466-1.37 1.15 0.826-1.61 1.15 0.826-1.61 1.84 1.18-2.88 0.00743 1.5 0.946-2.39 0.0844 1.69 1.07-2.66 0.0254 False False False False Both 188 1876 GRCh37/hg19 s=0.9;Lambda=0.04833 2020-06-08 prsweb-phecode150-ukbb-saige-hrc-x150-lassosum-mgi-20200608 prsweb-phecode150-ukbb-saige-hrc-x150-lassosum-mgi-20200608 PRSWEB_PHECODE150_UKBB-SAIGE-HRC-X150_LASSOSUM_MGI_20200608 Lassosum PRSWEB_PHECODE150_UKBB-SAIGE-HRC-X150_LASSOSUM_MGI_20200608 150 Cancer of esophagus Binary ICD9 and ICD10 based PheWAS codes MGI Michigan Genomics Initiative lassosum UKB GWAS (PheCode) UKB_GWAS https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761 64075 0.85 0.00246914 0.0828 0.502 0.457-0.546 OR 2.31 0.803-6.66 2.31 0.803-6.66 1.17 0.431-3.17 1.17 0.431-3.17 1.22 0.647-2.29 1.22 0.647-2.29 1.2 0.756-1.91 1.2 0.756-1.91 0.977 0.692-1.38 0.977 0.692-1.38 0.933 0.613-1.42 0.748 1.05 0.69-1.58 0.834 0.953 0.627-1.45 0.821 False False False False Both 188 1876 GRCh37/hg19 s=1;Lambda=0.04833 2020-06-08