prs_id slug legacy_id legacy_model prswebprefix trait_code trait_name trait_type description cohort cohort_label method gwas_source reference_label reference_url snp_count p_value pseudo_r2 brier_score mse aauc aauc_ci effect_metric top_effect_1 top_effect_1_ci top_or_1 top_or_1_ci top_effect_2 top_effect_2_ci top_or_2 top_or_2_ci top_effect_5 top_effect_5_ci top_or_5 top_or_5_ci top_effect_10 top_effect_10_ci top_or_10 top_or_10_ci top_effect_25 top_effect_25_ci top_or_25 top_or_25_ci q1_vs_q2_effect q1_vs_q2_effect_ci q1_vs_q2_p_value q1_vs_q3_effect q1_vs_q3_effect_ci q1_vs_q3_p_value q1_vs_q4_effect q1_vs_q4_effect_ci q1_vs_q4_p_value nominally_significant reversed_effect_warning underpowered_warning upload_to_portal sex cases controls genome_build tuning_parameter weights_external_url weights_url phewas_download_url exclusion_download_url last_updated prsweb-phecode153-2-20001-1022-p-5e-05-mgi-20200608 prsweb-phecode153-2-20001-1022-p-5e-05-mgi-20200608 PRSWEB_PHECODE153.2_20001-1022_P_5e-05_MGI_20200608 P_5e-05 PRSWEB_PHECODE153.2_20001-1022_P_5e-05_MGI_20200608 153.2 Cancer code, self-reported: colon cancer/sigmoid cancer Binary GWAS round 2: Results shared 1st August 2018. Imputed genotypes from HRC plus UK10K & 1000 Genomes reference panels as released by UK Biobank in March 2018. MGI Michigan Genomics Initiative Fixed threshold (5e-05) UKB GWAS (PHESANT) UKB_GWAS https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761 138 0.87 0.000122396 0.0833 0.496 0.47-0.525 OR 0.729 0.243-2.19 0.729 0.243-2.19 1.22 0.654-2.27 1.22 0.654-2.27 1.01 0.652-1.56 1.01 0.652-1.56 1 0.73-1.38 1 0.73-1.38 1.15 0.932-1.43 1.15 0.932-1.43 1.2 0.917-1.57 0.185 0.889 0.669-1.18 0.421 1.19 0.909-1.55 0.208 False False False False Both 462 4569 GRCh37/hg19 P<=5e-05 2020-06-08 prsweb-phecode153-2-c18-p-5e-05-mgi-20200608 prsweb-phecode153-2-c18-p-5e-05-mgi-20200608 PRSWEB_PHECODE153.2_C18_P_5e-05_MGI_20200608 P_5e-05 PRSWEB_PHECODE153.2_C18_P_5e-05_MGI_20200608 153.2 Diagnoses - main ICD10: C18 Malignant neoplasm of colon Binary GWAS round 2: Results shared 1st August 2018. Imputed genotypes from HRC plus UK10K & 1000 Genomes reference panels as released by UK Biobank in March 2018. MGI Michigan Genomics Initiative Fixed threshold (5e-05) UKB GWAS (ICD10) UKB_GWAS https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761 144 0.99 7.23153e-06 0.0833 0.497 0.47-0.525 OR 1.61 0.736-3.53 1.61 0.736-3.53 1.14 0.594-2.17 1.14 0.594-2.17 0.839 0.523-1.35 0.839 0.523-1.35 0.914 0.657-1.27 0.914 0.657-1.27 0.886 0.706-1.11 0.886 0.706-1.11 1.1 0.844-1.45 0.47 1.14 0.876-1.5 0.324 0.956 0.724-1.26 0.753 False False False False Both 462 4569 GRCh37/hg19 P<=5e-05 2020-06-08 prsweb-phecode153-2-c3-colon-p-5e-05-mgi-20200608 prsweb-phecode153-2-c3-colon-p-5e-05-mgi-20200608 PRSWEB_PHECODE153.2_C3-COLON_P_5e-05_MGI_20200608 P_5e-05 PRSWEB_PHECODE153.2_C3-COLON_P_5e-05_MGI_20200608 153.2 Malignant neoplasm of colon Binary GWAS round 2: Results shared 1st August 2018. Imputed genotypes from HRC plus UK10K & 1000 Genomes reference panels as released by UK Biobank in March 2018. MGI Michigan Genomics Initiative Fixed threshold (5e-05) UKB GWAS (FINNGEN) UKB_GWAS https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761 136 0.74 0.000680449 0.0833 0.507 0.481-0.536 OR 0.313 0.0606-1.61 0.313 0.0606-1.61 0.582 0.245-1.39 0.582 0.245-1.39 0.924 0.588-1.45 0.924 0.588-1.45 1.12 0.827-1.52 1.12 0.827-1.52 1.08 0.868-1.34 1.08 0.868-1.34 1 0.761-1.32 0.982 1.11 0.851-1.46 0.432 1.11 0.85-1.46 0.433 False False False False Both 462 4569 GRCh37/hg19 P<=5e-05 2020-06-08 prsweb-phecode153-2-ukbb-saige-hrc-x153-2-p-5e-05-mgi-20200608 prsweb-phecode153-2-ukbb-saige-hrc-x153-2-p-5e-05-mgi-20200608 PRSWEB_PHECODE153.2_UKBB-SAIGE-HRC-X153.2_P_5e-05_MGI_20200608 P_5e-05 PRSWEB_PHECODE153.2_UKBB-SAIGE-HRC-X153.2_P_5e-05_MGI_20200608 153.2 Colon cancer Binary ICD9 and ICD10 based PheWAS codes MGI Michigan Genomics Initiative Fixed threshold (5e-05) UKB GWAS (PheCode) UKB_GWAS https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761 127 0.0044 4.87739e-05 0.0832 0.536 0.509-0.565 OR 0.729 0.243-2.19 0.729 0.243-2.19 1.45 0.808-2.59 1.45 0.808-2.59 1.42 0.973-2.09 1.42 0.973-2.09 1.4 1.05-1.85 1.4 1.05-1.85 1.16 0.936-1.44 1.16 0.936-1.44 1.24 0.934-1.64 0.138 1.32 1-1.75 0.049 1.39 1.05-1.84 0.0198 True False False False Both 462 4569 GRCh37/hg19 P<=5e-05 2020-06-08 prsweb-phecode153-2-20001-1022-p-5e-06-mgi-20200608 prsweb-phecode153-2-20001-1022-p-5e-06-mgi-20200608 PRSWEB_PHECODE153.2_20001-1022_P_5e-06_MGI_20200608 P_5e-06 PRSWEB_PHECODE153.2_20001-1022_P_5e-06_MGI_20200608 153.2 Cancer code, self-reported: colon cancer/sigmoid cancer Binary GWAS round 2: Results shared 1st August 2018. Imputed genotypes from HRC plus UK10K & 1000 Genomes reference panels as released by UK Biobank in March 2018. MGI Michigan Genomics Initiative Fixed threshold (5e-06) UKB GWAS (PHESANT) UKB_GWAS https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761 18 0.85 0.00025859 0.0833 0.486 0.46-0.512 OR 0.514 0.142-1.86 0.514 0.142-1.86 0.904 0.444-1.84 0.904 0.444-1.84 0.875 0.551-1.39 0.875 0.551-1.39 0.983 0.713-1.35 0.983 0.713-1.35 1.01 0.809-1.26 1.01 0.809-1.26 0.893 0.677-1.18 0.424 1.13 0.869-1.47 0.36 1.02 0.777-1.33 0.895 False False False False Both 462 4569 GRCh37/hg19 P<=5e-06 2020-06-08 prsweb-phecode153-2-c18-p-5e-06-mgi-20200608 prsweb-phecode153-2-c18-p-5e-06-mgi-20200608 PRSWEB_PHECODE153.2_C18_P_5e-06_MGI_20200608 P_5e-06 PRSWEB_PHECODE153.2_C18_P_5e-06_MGI_20200608 153.2 Diagnoses - main ICD10: C18 Malignant neoplasm of colon Binary GWAS round 2: Results shared 1st August 2018. Imputed genotypes from HRC plus UK10K & 1000 Genomes reference panels as released by UK Biobank in March 2018. MGI Michigan Genomics Initiative Fixed threshold (5e-06) UKB GWAS (ICD10) UKB_GWAS https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761 24 0.49 0.000487952 0.0833 0.5 0.473-0.527 OR 0.966 0.362-2.58 0.966 0.362-2.58 1.25 0.669-2.33 1.25 0.669-2.33 1.15 0.76-1.74 1.15 0.76-1.74 1.05 0.769-1.44 1.05 0.769-1.44 1.1 0.89-1.37 1.1 0.89-1.37 1.01 0.769-1.32 0.964 0.932 0.709-1.23 0.617 1.08 0.825-1.4 0.591 False False False False Both 462 4569 GRCh37/hg19 P<=5e-06 2020-06-08 prsweb-phecode153-2-c3-colon-p-5e-06-mgi-20200608 prsweb-phecode153-2-c3-colon-p-5e-06-mgi-20200608 PRSWEB_PHECODE153.2_C3-COLON_P_5e-06_MGI_20200608 P_5e-06 PRSWEB_PHECODE153.2_C3-COLON_P_5e-06_MGI_20200608 153.2 Malignant neoplasm of colon Binary GWAS round 2: Results shared 1st August 2018. Imputed genotypes from HRC plus UK10K & 1000 Genomes reference panels as released by UK Biobank in March 2018. MGI Michigan Genomics Initiative Fixed threshold (5e-06) UKB GWAS (FINNGEN) UKB_GWAS https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761 25 0.11 0.000194416 0.0833 0.508 0.481-0.536 OR 1.16 0.473-2.84 1.16 0.473-2.84 1.11 0.582-2.13 1.11 0.582-2.13 1.09 0.719-1.67 1.09 0.719-1.67 1.3 0.972-1.74 1.3 0.972-1.74 1.06 0.855-1.32 1.06 0.855-1.32 1.06 0.802-1.39 0.695 1.14 0.871-1.5 0.334 1.12 0.856-1.47 0.402 False False False False Both 462 4569 GRCh37/hg19 P<=5e-06 2020-06-08 prsweb-phecode153-2-ukbb-saige-hrc-x153-2-p-5e-06-mgi-20200608 prsweb-phecode153-2-ukbb-saige-hrc-x153-2-p-5e-06-mgi-20200608 PRSWEB_PHECODE153.2_UKBB-SAIGE-HRC-X153.2_P_5e-06_MGI_20200608 P_5e-06 PRSWEB_PHECODE153.2_UKBB-SAIGE-HRC-X153.2_P_5e-06_MGI_20200608 153.2 Colon cancer Binary ICD9 and ICD10 based PheWAS codes MGI Michigan Genomics Initiative Fixed threshold (5e-06) UKB GWAS (PheCode) UKB_GWAS https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761 20 2.4e-06 0.0012952 0.083 0.559 0.532-0.586 OR 1.6 0.733-3.51 1.6 0.733-3.51 1.11 0.581-2.12 1.11 0.581-2.12 1.28 0.863-1.91 1.28 0.863-1.91 1.38 1.03-1.83 1.38 1.03-1.83 1.42 1.16-1.75 1.42 1.16-1.75 1.17 0.868-1.59 0.298 1.56 1.17-2.07 0.00235 1.79 1.35-2.36 4.81e-05 True False False False Both 462 4569 GRCh37/hg19 P<=5e-06 2020-06-08 prsweb-phecode153-2-20001-1022-pt-mgi-20200608 prsweb-phecode153-2-20001-1022-pt-mgi-20200608 PRSWEB_PHECODE153.2_20001-1022_PT_MGI_20200608 P&T PRSWEB_PHECODE153.2_20001-1022_PT_MGI_20200608 153.2 Cancer code, self-reported: colon cancer/sigmoid cancer Binary GWAS round 2: Results shared 1st August 2018. Imputed genotypes from HRC plus UK10K & 1000 Genomes reference panels as released by UK Biobank in March 2018. MGI Michigan Genomics Initiative P&T UKB GWAS (PHESANT) UKB_GWAS https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761 11 0.52 0.00105527 0.0833 0.492 0.467-0.521 OR 0.73 0.243-2.19 0.73 0.243-2.19 1 0.508-1.97 1 0.508-1.97 0.926 0.589-1.46 0.926 0.589-1.46 1.13 0.835-1.54 1.13 0.835-1.54 1.12 0.899-1.38 1.12 0.899-1.38 0.982 0.747-1.29 0.896 1.01 0.771-1.33 0.929 1.11 0.852-1.45 0.432 False False False False Both 462 4569 GRCh37/hg19 P<=3.16e-06 2020-06-08 prsweb-phecode153-2-c18-pt-mgi-20200608 prsweb-phecode153-2-c18-pt-mgi-20200608 PRSWEB_PHECODE153.2_C18_PT_MGI_20200608 P&T PRSWEB_PHECODE153.2_C18_PT_MGI_20200608 153.2 Diagnoses - main ICD10: C18 Malignant neoplasm of colon Binary GWAS round 2: Results shared 1st August 2018. Imputed genotypes from HRC plus UK10K & 1000 Genomes reference panels as released by UK Biobank in March 2018. MGI Michigan Genomics Initiative P&T UKB GWAS (ICD10) UKB_GWAS https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761 5 0.11 0.00219917 0.0833 0.508 0.482-0.535 OR 1.16 0.475-2.85 1.16 0.475-2.85 0.791 0.373-1.68 0.791 0.373-1.68 1.05 0.687-1.62 1.05 0.687-1.62 1.12 0.828-1.53 1.12 0.828-1.53 1.18 0.951-1.46 1.18 0.951-1.46 1.2 0.905-1.59 0.207 1.22 0.924-1.61 0.159 1.34 1.02-1.76 0.0362 False False False False Both 462 4569 GRCh37/hg19 P<=6.31e-07 2020-06-08 prsweb-phecode153-2-c3-colon-pt-mgi-20200608 prsweb-phecode153-2-c3-colon-pt-mgi-20200608 PRSWEB_PHECODE153.2_C3-COLON_PT_MGI_20200608 P&T PRSWEB_PHECODE153.2_C3-COLON_PT_MGI_20200608 153.2 Malignant neoplasm of colon Binary GWAS round 2: Results shared 1st August 2018. Imputed genotypes from HRC plus UK10K & 1000 Genomes reference panels as released by UK Biobank in March 2018. MGI Michigan Genomics Initiative P&T UKB GWAS (FINNGEN) UKB_GWAS https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761 18 0.1 0.00164706 0.0833 0.513 0.485-0.541 OR 1.18 0.482-2.9 1.18 0.482-2.9 1.24 0.667-2.31 1.24 0.667-2.31 1.19 0.794-1.8 1.19 0.794-1.8 1.05 0.769-1.44 1.05 0.769-1.44 1.13 0.908-1.39 1.13 0.908-1.39 1.17 0.883-1.55 0.272 1.33 1.01-1.75 0.0415 1.29 0.981-1.71 0.0684 False False False False Both 462 4569 GRCh37/hg19 P<=2.51e-06 2020-06-08 prsweb-phecode153-2-ukbb-saige-hrc-x153-2-pt-mgi-20200608 prsweb-phecode153-2-ukbb-saige-hrc-x153-2-pt-mgi-20200608 PRSWEB_PHECODE153.2_UKBB-SAIGE-HRC-X153.2_PT_MGI_20200608 P&T PRSWEB_PHECODE153.2_UKBB-SAIGE-HRC-X153.2_PT_MGI_20200608 153.2 Colon cancer Binary ICD9 and ICD10 based PheWAS codes MGI Michigan Genomics Initiative P&T UKB GWAS (PheCode) UKB_GWAS https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761 12 4.4e-05 0.00314441 0.0831 0.55 0.522-0.577 OR 1.6 0.733-3.51 1.6 0.733-3.51 1.68 0.971-2.91 1.68 0.971-2.91 1.28 0.863-1.9 1.28 0.863-1.9 1.29 0.966-1.73 1.29 0.966-1.73 1.5 1.22-1.84 1.5 1.22-1.84 1.28 0.951-1.71 0.105 1.38 1.04-1.85 0.0279 1.83 1.39-2.42 1.85e-05 True False False True Both 462 4569 GRCh37/hg19 P<=2e-06 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000381/ScoringFiles/ https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000381/ScoringFiles/ /larsf/prsweb-data/cancerprsweb/releases/cancerprsweb_20200608/phewas/PRSWEB_PHECODE153.2_UKBB-SAIGE-HRC-X153.2_PT_MGI_20200608/all.tsv /larsf/prsweb-data/cancerprsweb/releases/cancerprsweb_20200608/phewas/PRSWEB_PHECODE153.2_UKBB-SAIGE-HRC-X153.2_PT_MGI_20200608/exclusion.tsv 2020-06-08 prsweb-phecode153-2-20001-1022-prs-cs-mgi-20200608 prsweb-phecode153-2-20001-1022-prs-cs-mgi-20200608 PRSWEB_PHECODE153.2_20001-1022_PRS-CS_MGI_20200608 PRS-CS PRSWEB_PHECODE153.2_20001-1022_PRS-CS_MGI_20200608 153.2 Cancer code, self-reported: colon cancer/sigmoid cancer Binary GWAS round 2: Results shared 1st August 2018. Imputed genotypes from HRC plus UK10K & 1000 Genomes reference panels as released by UK Biobank in March 2018. MGI Michigan Genomics Initiative PRS-CS UKB GWAS (PHESANT) UKB_GWAS https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761 1104674 0.074 0.00159419 0.0833 0.517 0.489-0.544 OR 2.7 1.43-5.11 2.7 1.43-5.11 2.23 1.37-3.65 2.23 1.37-3.65 1.48 1.02-2.15 1.48 1.02-2.15 1.14 0.846-1.55 1.14 0.846-1.55 1.09 0.88-1.36 1.09 0.88-1.36 1.1 0.84-1.45 0.479 1.03 0.785-1.36 0.813 1.14 0.87-1.49 0.341 False False False False Both 462 4569 GRCh37/hg19 auto 2020-06-08 prsweb-phecode153-2-c18-prs-cs-mgi-20200608 prsweb-phecode153-2-c18-prs-cs-mgi-20200608 PRSWEB_PHECODE153.2_C18_PRS-CS_MGI_20200608 PRS-CS PRSWEB_PHECODE153.2_C18_PRS-CS_MGI_20200608 153.2 Diagnoses - main ICD10: C18 Malignant neoplasm of colon Binary GWAS round 2: Results shared 1st August 2018. Imputed genotypes from HRC plus UK10K & 1000 Genomes reference panels as released by UK Biobank in March 2018. MGI Michigan Genomics Initiative PRS-CS UKB GWAS (ICD10) UKB_GWAS https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761 1111490 0.00089 0.00299079 0.0832 0.547 0.518-0.576 OR 1.65 0.753-3.61 1.65 0.753-3.61 1.36 0.746-2.48 1.36 0.746-2.48 1.53 1.05-2.22 1.53 1.05-2.22 1.43 1.08-1.89 1.43 1.08-1.89 1.23 0.999-1.52 1.23 0.999-1.52 1.26 0.946-1.69 0.114 1.42 1.07-1.89 0.0137 1.53 1.15-2.02 0.00302 True False False True Both 462 4569 GRCh37/hg19 auto https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000376/ScoringFiles/ https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000376/ScoringFiles/ /larsf/prsweb-data/cancerprsweb/releases/cancerprsweb_20200608/phewas/PRSWEB_PHECODE153.2_C18_PRS-CS_MGI_20200608/all.tsv /larsf/prsweb-data/cancerprsweb/releases/cancerprsweb_20200608/phewas/PRSWEB_PHECODE153.2_C18_PRS-CS_MGI_20200608/exclusion.tsv 2020-06-08 prsweb-phecode153-2-c3-colon-prs-cs-mgi-20200608 prsweb-phecode153-2-c3-colon-prs-cs-mgi-20200608 PRSWEB_PHECODE153.2_C3-COLON_PRS-CS_MGI_20200608 PRS-CS PRSWEB_PHECODE153.2_C3-COLON_PRS-CS_MGI_20200608 153.2 Malignant neoplasm of colon Binary GWAS round 2: Results shared 1st August 2018. Imputed genotypes from HRC plus UK10K & 1000 Genomes reference panels as released by UK Biobank in March 2018. MGI Michigan Genomics Initiative PRS-CS UKB GWAS (FINNGEN) UKB_GWAS https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761 1111399 0.0065 0.00373392 0.0832 0.536 0.509-0.565 OR 1.82 0.867-3.84 1.82 0.867-3.84 1.92 1.14-3.24 1.92 1.14-3.24 1.64 1.14-2.35 1.64 1.14-2.35 1.16 0.855-1.57 1.16 0.855-1.57 1.2 0.967-1.48 1.2 0.967-1.48 1.45 1.09-1.93 0.011 1.41 1.06-1.88 0.019 1.54 1.16-2.04 0.00282 True False False True Both 462 4569 GRCh37/hg19 auto https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000378/ScoringFiles/ https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000378/ScoringFiles/ /larsf/prsweb-data/cancerprsweb/releases/cancerprsweb_20200608/phewas/PRSWEB_PHECODE153.2_C3-COLON_PRS-CS_MGI_20200608/all.tsv /larsf/prsweb-data/cancerprsweb/releases/cancerprsweb_20200608/phewas/PRSWEB_PHECODE153.2_C3-COLON_PRS-CS_MGI_20200608/exclusion.tsv 2020-06-08 prsweb-phecode153-2-ukbb-saige-hrc-x153-2-prs-cs-mgi-20200608 prsweb-phecode153-2-ukbb-saige-hrc-x153-2-prs-cs-mgi-20200608 PRSWEB_PHECODE153.2_UKBB-SAIGE-HRC-X153.2_PRS-CS_MGI_20200608 PRS-CS PRSWEB_PHECODE153.2_UKBB-SAIGE-HRC-X153.2_PRS-CS_MGI_20200608 153.2 Colon cancer Binary ICD9 and ICD10 based PheWAS codes MGI Michigan Genomics Initiative PRS-CS UKB GWAS (PheCode) UKB_GWAS https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761 1119238 9.8e-09 0.00231342 0.0827 0.569 0.539-0.599 OR 3.85 2.19-6.77 3.85 2.19-6.77 3.32 2.16-5.09 3.32 2.16-5.09 2.42 1.76-3.32 2.42 1.76-3.32 1.84 1.42-2.4 1.84 1.42-2.4 1.42 1.16-1.75 1.42 1.16-1.75 1.4 1.04-1.88 0.0281 1.6 1.19-2.14 0.00169 1.94 1.46-2.58 5.89e-06 True False False True Both 462 4569 GRCh37/hg19 auto https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000380/ScoringFiles/ https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000380/ScoringFiles/ /larsf/prsweb-data/cancerprsweb/releases/cancerprsweb_20200608/phewas/PRSWEB_PHECODE153.2_UKBB-SAIGE-HRC-X153.2_PRS-CS_MGI_20200608/all.tsv /larsf/prsweb-data/cancerprsweb/releases/cancerprsweb_20200608/phewas/PRSWEB_PHECODE153.2_UKBB-SAIGE-HRC-X153.2_PRS-CS_MGI_20200608/exclusion.tsv 2020-06-08 prsweb-phecode153-2-20001-1022-lassosum-mgi-20200608 prsweb-phecode153-2-20001-1022-lassosum-mgi-20200608 PRSWEB_PHECODE153.2_20001-1022_LASSOSUM_MGI_20200608 Lassosum PRSWEB_PHECODE153.2_20001-1022_LASSOSUM_MGI_20200608 153.2 Cancer code, self-reported: colon cancer/sigmoid cancer Binary GWAS round 2: Results shared 1st August 2018. Imputed genotypes from HRC plus UK10K & 1000 Genomes reference panels as released by UK Biobank in March 2018. MGI Michigan Genomics Initiative lassosum UKB GWAS (PHESANT) UKB_GWAS https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761 5818307 0.37 0.000882096 0.0833 0.513 0.485-0.538 OR 0.948 0.356-2.53 0.948 0.356-2.53 1.13 0.591-2.16 1.13 0.591-2.16 1.11 0.727-1.69 1.11 0.727-1.69 0.889 0.637-1.24 0.889 0.637-1.24 1.07 0.859-1.33 1.07 0.859-1.33 1.1 0.835-1.46 0.488 1.24 0.941-1.63 0.127 1.19 0.906-1.57 0.21 False False False False Both 462 4569 GRCh37/hg19 s=1;Lambda=0.001 2020-06-08 prsweb-phecode153-2-c18-lassosum-mgi-20200608 prsweb-phecode153-2-c18-lassosum-mgi-20200608 PRSWEB_PHECODE153.2_C18_LASSOSUM_MGI_20200608 Lassosum PRSWEB_PHECODE153.2_C18_LASSOSUM_MGI_20200608 153.2 Diagnoses - main ICD10: C18 Malignant neoplasm of colon Binary GWAS round 2: Results shared 1st August 2018. Imputed genotypes from HRC plus UK10K & 1000 Genomes reference panels as released by UK Biobank in March 2018. MGI Michigan Genomics Initiative lassosum UKB GWAS (ICD10) UKB_GWAS https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761 5740814 0.0011 0.00245316 0.0831 0.545 0.518-0.574 OR 1.4 0.607-3.22 1.4 0.607-3.22 1.37 0.751-2.5 1.37 0.751-2.5 1.53 1.06-2.23 1.53 1.06-2.23 1.6 1.22-2.1 1.6 1.22-2.1 1.45 1.18-1.78 1.45 1.18-1.78 0.877 0.656-1.17 0.378 1.1 0.839-1.45 0.48 1.43 1.1-1.86 0.00702 True False False True Both 462 4569 GRCh37/hg19 s=1;Lambda=0.001 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000377/ScoringFiles/ https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000377/ScoringFiles/ /larsf/prsweb-data/cancerprsweb/releases/cancerprsweb_20200608/phewas/PRSWEB_PHECODE153.2_C18_LASSOSUM_MGI_20200608/all.tsv /larsf/prsweb-data/cancerprsweb/releases/cancerprsweb_20200608/phewas/PRSWEB_PHECODE153.2_C18_LASSOSUM_MGI_20200608/exclusion.tsv 2020-06-08 prsweb-phecode153-2-c3-colon-lassosum-mgi-20200608 prsweb-phecode153-2-c3-colon-lassosum-mgi-20200608 PRSWEB_PHECODE153.2_C3-COLON_LASSOSUM_MGI_20200608 Lassosum PRSWEB_PHECODE153.2_C3-COLON_LASSOSUM_MGI_20200608 153.2 Malignant neoplasm of colon Binary GWAS round 2: Results shared 1st August 2018. Imputed genotypes from HRC plus UK10K & 1000 Genomes reference panels as released by UK Biobank in March 2018. MGI Michigan Genomics Initiative lassosum UKB GWAS (FINNGEN) UKB_GWAS https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761 5715093 0.0064 0.00263802 0.0832 0.536 0.51-0.567 OR 0.757 0.252-2.28 0.757 0.252-2.28 1.04 0.53-2.06 1.04 0.53-2.06 1.55 1.07-2.25 1.55 1.07-2.25 1.39 1.04-1.84 1.39 1.04-1.84 1.38 1.12-1.7 1.38 1.12-1.7 1.1 0.833-1.46 0.496 1.02 0.766-1.35 0.906 1.45 1.11-1.89 0.00607 True False False True Both 462 4569 GRCh37/hg19 s=1;Lambda=0.001 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000379/ScoringFiles/ https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000379/ScoringFiles/ /larsf/prsweb-data/cancerprsweb/releases/cancerprsweb_20200608/phewas/PRSWEB_PHECODE153.2_C3-COLON_LASSOSUM_MGI_20200608/all.tsv /larsf/prsweb-data/cancerprsweb/releases/cancerprsweb_20200608/phewas/PRSWEB_PHECODE153.2_C3-COLON_LASSOSUM_MGI_20200608/exclusion.tsv 2020-06-08 prsweb-phecode153-2-ukbb-saige-hrc-x153-2-lassosum-mgi-20200608 prsweb-phecode153-2-ukbb-saige-hrc-x153-2-lassosum-mgi-20200608 PRSWEB_PHECODE153.2_UKBB-SAIGE-HRC-X153.2_LASSOSUM_MGI_20200608 Lassosum PRSWEB_PHECODE153.2_UKBB-SAIGE-HRC-X153.2_LASSOSUM_MGI_20200608 153.2 Colon cancer Binary ICD9 and ICD10 based PheWAS codes MGI Michigan Genomics Initiative lassosum UKB GWAS (PheCode) UKB_GWAS https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761 150 4.9e-06 0.00231173 0.083 0.567 0.54-0.594 OR 1.17 0.477-2.87 1.17 0.477-2.87 1.12 0.587-2.15 1.12 0.587-2.15 1.47 1.01-2.14 1.47 1.01-2.14 1.46 1.1-1.93 1.46 1.1-1.93 1.55 1.26-1.9 1.55 1.26-1.9 1.34 0.989-1.81 0.059 1.55 1.16-2.08 0.00349 2 1.51-2.66 1.34e-06 True False False True Both 462 4569 GRCh37/hg19 s=0.2;Lambda=0.03793 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000382/ScoringFiles/ https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000382/ScoringFiles/ /larsf/prsweb-data/cancerprsweb/releases/cancerprsweb_20200608/phewas/PRSWEB_PHECODE153.2_UKBB-SAIGE-HRC-X153.2_LASSOSUM_MGI_20200608/all.tsv /larsf/prsweb-data/cancerprsweb/releases/cancerprsweb_20200608/phewas/PRSWEB_PHECODE153.2_UKBB-SAIGE-HRC-X153.2_LASSOSUM_MGI_20200608/exclusion.tsv 2020-06-08