prs_id slug legacy_id legacy_model prswebprefix trait_code trait_name trait_type description cohort cohort_label method gwas_source reference_label reference_url snp_count p_value pseudo_r2 brier_score mse aauc aauc_ci effect_metric top_effect_1 top_effect_1_ci top_or_1 top_or_1_ci top_effect_2 top_effect_2_ci top_or_2 top_or_2_ci top_effect_5 top_effect_5_ci top_or_5 top_or_5_ci top_effect_10 top_effect_10_ci top_or_10 top_or_10_ci top_effect_25 top_effect_25_ci top_or_25 top_or_25_ci q1_vs_q2_effect q1_vs_q2_effect_ci q1_vs_q2_p_value q1_vs_q3_effect q1_vs_q3_effect_ci q1_vs_q3_p_value q1_vs_q4_effect q1_vs_q4_effect_ci q1_vs_q4_p_value nominally_significant reversed_effect_warning underpowered_warning upload_to_portal sex cases controls genome_build tuning_parameter weights_external_url weights_url phewas_download_url exclusion_download_url last_updated prsweb-phecode153-crc-huyghe-p-5e-05-ukb-20200608 prsweb-phecode153-crc-huyghe-p-5e-05-ukb-20200608 PRSWEB_PHECODE153_CRC-Huyghe_P_5e-05_UKB_20200608 P_5e-05 PRSWEB_PHECODE153_CRC-Huyghe_P_5e-05_UKB_20200608 153 Colorectal cancer Binary Supplementary Tables 11 & 15; Cases: Discovery: 34,869; Follow-up: 23,262; Controls: Discovery: 29,051; Follow-up: 38,296 controls UKB UK Biobank Fixed threshold (5e-05) Huyghe JR et al. 2019 30510241 https://www.ncbi.nlm.nih.gov/pubmed/?term=30510241 87 4.5e-83 0.0336057 0.0812 0.617 0.605-0.63 OR 4 3.11-5.13 4 3.11-5.13 3.4 2.8-4.11 3.4 2.8-4.11 2.69 2.34-3.08 2.69 2.34-3.08 2.35 2.11-2.63 2.35 2.11-2.63 1.99 1.82-2.18 1.99 1.82-2.18 1.34 1.16-1.55 8.6e-05 1.72 1.5-1.98 2.19e-14 2.69 2.36-3.07 3.06e-50 True False False False Both 2271 22725 GRCh37/hg19 P<=5e-05 2020-06-08 prsweb-phecode153-gwas-catalog-r2019-05-03-x153-p-5e-05-ukb-20200608 prsweb-phecode153-gwas-catalog-r2019-05-03-x153-p-5e-05-ukb-20200608 PRSWEB_PHECODE153_GWAS-Catalog-r2019-05-03-X153_P_5e-05_UKB_20200608 P_5e-05 PRSWEB_PHECODE153_GWAS-Catalog-r2019-05-03-X153_P_5e-05_UKB_20200608 153 Colorectal cancer Binary 37 unique SNPs UKB UK Biobank Fixed threshold (5e-05) GWAS Catalog (2019-05-03) 17618284;17934461;18372901;19011631;23266556;24737748;25990418;26151821;28960316 https://www.ncbi.nlm.nih.gov/pubmed/?term=17618284+17934461+18372901+19011631+23266556+24737748+25990418+26151821+28960316 27 1.3e-29 0.0134858 0.0822 0.565 0.551-0.577 OR 2.1 1.53-2.89 2.1 1.53-2.89 2.1 1.67-2.63 2.1 1.67-2.63 1.75 1.49-2.05 1.75 1.49-2.05 1.69 1.5-1.91 1.69 1.5-1.91 1.53 1.4-1.68 1.53 1.4-1.68 1.16 1.02-1.33 0.0273 1.33 1.17-1.52 1.5e-05 1.78 1.58-2.02 4.39e-20 True False False False Both 2271 22725 GRCh37/hg19 P<=5e-05 2020-06-08 prsweb-phecode153-crc-huyghe-p-5e-06-ukb-20200608 prsweb-phecode153-crc-huyghe-p-5e-06-ukb-20200608 PRSWEB_PHECODE153_CRC-Huyghe_P_5e-06_UKB_20200608 P_5e-06 PRSWEB_PHECODE153_CRC-Huyghe_P_5e-06_UKB_20200608 153 Colorectal cancer Binary Supplementary Tables 11 & 15; Cases: Discovery: 34,869; Follow-up: 23,262; Controls: Discovery: 29,051; Follow-up: 38,296 controls UKB UK Biobank Fixed threshold (5e-06) Huyghe JR et al. 2019 30510241 https://www.ncbi.nlm.nih.gov/pubmed/?term=30510241 85 1.7e-82 0.0334415 0.0812 0.617 0.605-0.63 OR 3.85 2.99-4.96 3.85 2.99-4.96 3.44 2.85-4.17 3.44 2.85-4.17 2.69 2.34-3.08 2.69 2.34-3.08 2.31 2.07-2.58 2.31 2.07-2.58 2 1.83-2.18 2 1.83-2.18 1.36 1.18-1.58 3.81e-05 1.79 1.55-2.05 4.19e-16 2.75 2.41-3.14 1.15e-51 True False False False Both 2271 22725 GRCh37/hg19 P<=5e-06 2020-06-08 prsweb-phecode153-gwas-catalog-r2019-05-03-x153-p-5e-06-ukb-20200608 prsweb-phecode153-gwas-catalog-r2019-05-03-x153-p-5e-06-ukb-20200608 PRSWEB_PHECODE153_GWAS-Catalog-r2019-05-03-X153_P_5e-06_UKB_20200608 P_5e-06 PRSWEB_PHECODE153_GWAS-Catalog-r2019-05-03-X153_P_5e-06_UKB_20200608 153 Colorectal cancer Binary 37 unique SNPs UKB UK Biobank Fixed threshold (5e-06) GWAS Catalog (2019-05-03) 17618284;17934461;18372901;19011631;23266556;24737748;25990418;26151821;28960316 https://www.ncbi.nlm.nih.gov/pubmed/?term=17618284+17934461+18372901+19011631+23266556+24737748+25990418+26151821+28960316 26 3.1e-29 0.0133918 0.0822 0.564 0.551-0.577 OR 2.1 1.53-2.89 2.1 1.53-2.89 2.05 1.63-2.58 2.05 1.63-2.58 1.78 1.52-2.08 1.78 1.52-2.08 1.69 1.49-1.9 1.69 1.49-1.9 1.53 1.4-1.68 1.53 1.4-1.68 1.17 1.02-1.34 0.0211 1.35 1.18-1.54 6.56e-06 1.8 1.59-2.03 1.95e-20 True False False False Both 2271 22725 GRCh37/hg19 P<=5e-06 2020-06-08 prsweb-phecode153-crc-huyghe-p-5e-07-ukb-20200608 prsweb-phecode153-crc-huyghe-p-5e-07-ukb-20200608 PRSWEB_PHECODE153_CRC-Huyghe_P_5e-07_UKB_20200608 P_5e-07 PRSWEB_PHECODE153_CRC-Huyghe_P_5e-07_UKB_20200608 153 Colorectal cancer Binary Supplementary Tables 11 & 15; Cases: Discovery: 34,869; Follow-up: 23,262; Controls: Discovery: 29,051; Follow-up: 38,296 controls UKB UK Biobank Fixed threshold (5e-07) Huyghe JR et al. 2019 30510241 https://www.ncbi.nlm.nih.gov/pubmed/?term=30510241 81 6.6e-81 0.0330113 0.0812 0.616 0.604-0.629 OR 3.85 2.99-4.96 3.85 2.99-4.96 3.3 2.72-4 3.3 2.72-4 2.66 2.32-3.06 2.66 2.32-3.06 2.36 2.11-2.63 2.36 2.11-2.63 2.03 1.86-2.22 2.03 1.86-2.22 1.32 1.14-1.53 0.000253 1.78 1.54-2.04 7.02e-16 2.76 2.43-3.15 2.1e-52 True False False False Both 2271 22725 GRCh37/hg19 P<=5e-07 2020-06-08 prsweb-phecode153-gwas-catalog-r2019-05-03-x153-p-5e-07-ukb-20200608 prsweb-phecode153-gwas-catalog-r2019-05-03-x153-p-5e-07-ukb-20200608 PRSWEB_PHECODE153_GWAS-Catalog-r2019-05-03-X153_P_5e-07_UKB_20200608 P_5e-07 PRSWEB_PHECODE153_GWAS-Catalog-r2019-05-03-X153_P_5e-07_UKB_20200608 153 Colorectal cancer Binary 37 unique SNPs UKB UK Biobank Fixed threshold (5e-07) GWAS Catalog (2019-05-03) 17618284;17934461;18372901;19011631;23266556;24737748;25990418;26151821;28960316 https://www.ncbi.nlm.nih.gov/pubmed/?term=17618284+17934461+18372901+19011631+23266556+24737748+25990418+26151821+28960316 22 8.7e-26 0.0118471 0.0822 0.561 0.548-0.573 OR 1.65 1.17-2.34 1.65 1.17-2.34 1.94 1.53-2.45 1.94 1.53-2.45 1.6 1.36-1.89 1.6 1.36-1.89 1.69 1.49-1.9 1.69 1.49-1.9 1.49 1.36-1.63 1.49 1.36-1.63 1.19 1.04-1.36 0.0113 1.36 1.19-1.55 4.08e-06 1.75 1.55-1.99 6.71e-19 True False False False Both 2271 22725 GRCh37/hg19 P<=5e-07 2020-06-08 prsweb-phecode153-crc-huyghe-p-5e-09-ukb-20200608 prsweb-phecode153-crc-huyghe-p-5e-09-ukb-20200608 PRSWEB_PHECODE153_CRC-Huyghe_P_5e-09_UKB_20200608 P_5e-09 PRSWEB_PHECODE153_CRC-Huyghe_P_5e-09_UKB_20200608 153 Colorectal cancer Binary Supplementary Tables 11 & 15; Cases: Discovery: 34,869; Follow-up: 23,262; Controls: Discovery: 29,051; Follow-up: 38,296 controls UKB UK Biobank Fixed threshold (5e-09) Huyghe JR et al. 2019 30510241 https://www.ncbi.nlm.nih.gov/pubmed/?term=30510241 56 4.8e-69 0.0274185 0.0814 0.607 0.594-0.62 OR 3.39 2.6-4.41 3.39 2.6-4.41 2.86 2.33-3.5 2.86 2.33-3.5 2.55 2.22-2.94 2.55 2.22-2.94 2.21 1.97-2.47 2.21 1.97-2.47 1.9 1.74-2.08 1.9 1.74-2.08 1.48 1.28-1.71 8.54e-08 1.74 1.51-2.01 8.43e-15 2.67 2.34-3.05 1.73e-48 True False False False Both 2271 22725 GRCh37/hg19 P<=5e-09 2020-06-08 prsweb-phecode153-gwas-catalog-r2019-05-03-x153-p-5e-09-ukb-20200608 prsweb-phecode153-gwas-catalog-r2019-05-03-x153-p-5e-09-ukb-20200608 PRSWEB_PHECODE153_GWAS-Catalog-r2019-05-03-X153_P_5e-09_UKB_20200608 P_5e-09 PRSWEB_PHECODE153_GWAS-Catalog-r2019-05-03-X153_P_5e-09_UKB_20200608 153 Colorectal cancer Binary 37 unique SNPs UKB UK Biobank Fixed threshold (5e-09) GWAS Catalog (2019-05-03) 17618284;17934461;18372901;19011631;23266556;24737748;25990418;26151821;28960316 https://www.ncbi.nlm.nih.gov/pubmed/?term=17618284+17934461+18372901+19011631+23266556+24737748+25990418+26151821+28960316 12 9.7e-25 0.0111996 0.0822 0.56 0.547-0.572 OR 1.79 1.28-2.51 1.79 1.28-2.51 1.73 1.35-2.21 1.73 1.35-2.21 1.64 1.39-1.93 1.64 1.39-1.93 1.67 1.48-1.89 1.67 1.48-1.89 1.48 1.35-1.63 1.48 1.35-1.63 1.24 1.08-1.41 0.00174 1.36 1.2-1.55 3.47e-06 1.78 1.57-2.02 1.09e-19 True False False False Both 2271 22725 GRCh37/hg19 P<=5e-09 2020-06-08 prsweb-phecode153-crc-huyghe-p-5e-08-ukb-20200608 prsweb-phecode153-crc-huyghe-p-5e-08-ukb-20200608 PRSWEB_PHECODE153_CRC-Huyghe_P_5e-08_UKB_20200608 P_5e-08 PRSWEB_PHECODE153_CRC-Huyghe_P_5e-08_UKB_20200608 153 Colorectal cancer Binary Supplementary Tables 11 & 15; Cases: Discovery: 34,869; Follow-up: 23,262; Controls: Discovery: 29,051; Follow-up: 38,296 controls UKB UK Biobank GWAS Hits Huyghe JR et al. 2019 30510241 https://www.ncbi.nlm.nih.gov/pubmed/?term=30510241 74 3.6e-76 0.0310016 0.0813 0.612 0.6-0.625 OR 3.85 2.99-4.96 3.85 2.99-4.96 3.17 2.61-3.86 3.17 2.61-3.86 2.71 2.36-3.11 2.71 2.36-3.11 2.29 2.05-2.56 2.29 2.05-2.56 1.98 1.81-2.17 1.98 1.81-2.17 1.3 1.12-1.5 0.000434 1.7 1.48-1.95 7.25e-14 2.64 2.32-3.01 7.83e-49 True False False True Both 2271 22725 GRCh37/hg19 P<=5e-08 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000368/ScoringFiles/ https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000368/ScoringFiles/ /larsf/prsweb-data/cancerprsweb/releases/cancerprsweb_20200608/phewas/PRSWEB_PHECODE153_CRC-Huyghe_P_5e-08_UKB_20200608/all.tsv /larsf/prsweb-data/cancerprsweb/releases/cancerprsweb_20200608/phewas/PRSWEB_PHECODE153_CRC-Huyghe_P_5e-08_UKB_20200608/exclusion.tsv 2020-06-08 prsweb-phecode153-gwas-catalog-r2019-05-03-x153-p-5e-08-ukb-20200608 prsweb-phecode153-gwas-catalog-r2019-05-03-x153-p-5e-08-ukb-20200608 PRSWEB_PHECODE153_GWAS-Catalog-r2019-05-03-X153_P_5e-08_UKB_20200608 P_5e-08 PRSWEB_PHECODE153_GWAS-Catalog-r2019-05-03-X153_P_5e-08_UKB_20200608 153 Colorectal cancer Binary 37 unique SNPs UKB UK Biobank GWAS Hits GWAS Catalog (2019-05-03) 17618284;17934461;18372901;19011631;23266556;24737748;25990418;26151821;28960316 https://www.ncbi.nlm.nih.gov/pubmed/?term=17618284+17934461+18372901+19011631+23266556+24737748+25990418+26151821+28960316 18 1.9e-25 0.0116021 0.0822 0.561 0.548-0.573 OR 1.79 1.28-2.51 1.79 1.28-2.51 1.77 1.39-2.26 1.77 1.39-2.26 1.64 1.39-1.93 1.64 1.39-1.93 1.59 1.4-1.79 1.59 1.4-1.79 1.49 1.35-1.63 1.49 1.35-1.63 1.13 0.992-1.3 0.0664 1.36 1.19-1.54 3.39e-06 1.72 1.52-1.95 5.31e-18 True False False True Both 2271 22725 GRCh37/hg19 P<=5e-08 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000371/ScoringFiles/ https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000371/ScoringFiles/ /larsf/prsweb-data/cancerprsweb/releases/cancerprsweb_20200608/phewas/PRSWEB_PHECODE153_GWAS-Catalog-r2019-05-03-X153_P_5e-08_UKB_20200608/all.tsv /larsf/prsweb-data/cancerprsweb/releases/cancerprsweb_20200608/phewas/PRSWEB_PHECODE153_GWAS-Catalog-r2019-05-03-X153_P_5e-08_UKB_20200608/exclusion.tsv 2020-06-08 prsweb-phecode153-crc-huyghe-pt-ukb-20200608 prsweb-phecode153-crc-huyghe-pt-ukb-20200608 PRSWEB_PHECODE153_CRC-Huyghe_PT_UKB_20200608 P&T PRSWEB_PHECODE153_CRC-Huyghe_PT_UKB_20200608 153 Colorectal cancer Binary Supplementary Tables 11 & 15; Cases: Discovery: 34,869; Follow-up: 23,262; Controls: Discovery: 29,051; Follow-up: 38,296 controls UKB UK Biobank P&T Huyghe JR et al. 2019 30510241 https://www.ncbi.nlm.nih.gov/pubmed/?term=30510241 87 4.5e-83 0.0336057 0.0812 0.617 0.605-0.63 OR 4 3.11-5.13 4 3.11-5.13 3.4 2.8-4.11 3.4 2.8-4.11 2.69 2.34-3.08 2.69 2.34-3.08 2.35 2.11-2.63 2.35 2.11-2.63 1.99 1.82-2.18 1.99 1.82-2.18 1.34 1.16-1.55 8.6e-05 1.72 1.5-1.98 2.19e-14 2.69 2.36-3.07 3.06e-50 True False False True Both 2271 22725 GRCh37/hg19 P<=7.8e-06 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000370/ScoringFiles/ https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000370/ScoringFiles/ /larsf/prsweb-data/cancerprsweb/releases/cancerprsweb_20200608/phewas/PRSWEB_PHECODE153_CRC-Huyghe_PT_UKB_20200608/all.tsv /larsf/prsweb-data/cancerprsweb/releases/cancerprsweb_20200608/phewas/PRSWEB_PHECODE153_CRC-Huyghe_PT_UKB_20200608/exclusion.tsv 2020-06-08 prsweb-phecode153-gwas-catalog-r2019-05-03-x153-pt-ukb-20200608 prsweb-phecode153-gwas-catalog-r2019-05-03-x153-pt-ukb-20200608 PRSWEB_PHECODE153_GWAS-Catalog-r2019-05-03-X153_PT_UKB_20200608 P&T PRSWEB_PHECODE153_GWAS-Catalog-r2019-05-03-X153_PT_UKB_20200608 153 Colorectal cancer Binary 37 unique SNPs UKB UK Biobank P&T GWAS Catalog (2019-05-03) 17618284;17934461;18372901;19011631;23266556;24737748;25990418;26151821;28960316 https://www.ncbi.nlm.nih.gov/pubmed/?term=17618284+17934461+18372901+19011631+23266556+24737748+25990418+26151821+28960316 27 1.3e-29 0.0134858 0.0822 0.565 0.551-0.577 OR 2.1 1.53-2.89 2.1 1.53-2.89 2.1 1.67-2.63 2.1 1.67-2.63 1.75 1.49-2.05 1.75 1.49-2.05 1.69 1.5-1.91 1.69 1.5-1.91 1.53 1.4-1.68 1.53 1.4-1.68 1.16 1.02-1.33 0.0273 1.33 1.17-1.52 1.5e-05 1.78 1.58-2.02 4.39e-20 True False False True Both 2271 22725 GRCh37/hg19 P<=7e-06 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000372/ScoringFiles/ https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000372/ScoringFiles/ /larsf/prsweb-data/cancerprsweb/releases/cancerprsweb_20200608/phewas/PRSWEB_PHECODE153_GWAS-Catalog-r2019-05-03-X153_PT_UKB_20200608/all.tsv /larsf/prsweb-data/cancerprsweb/releases/cancerprsweb_20200608/phewas/PRSWEB_PHECODE153_GWAS-Catalog-r2019-05-03-X153_PT_UKB_20200608/exclusion.tsv 2020-06-08