prs_id slug legacy_id legacy_model prswebprefix trait_code trait_name trait_type description cohort cohort_label method gwas_source reference_label reference_url snp_count p_value pseudo_r2 brier_score mse aauc aauc_ci effect_metric top_effect_1 top_effect_1_ci top_or_1 top_or_1_ci top_effect_2 top_effect_2_ci top_or_2 top_or_2_ci top_effect_5 top_effect_5_ci top_or_5 top_or_5_ci top_effect_10 top_effect_10_ci top_or_10 top_or_10_ci top_effect_25 top_effect_25_ci top_or_25 top_or_25_ci q1_vs_q2_effect q1_vs_q2_effect_ci q1_vs_q2_p_value q1_vs_q3_effect q1_vs_q3_effect_ci q1_vs_q3_p_value q1_vs_q4_effect q1_vs_q4_effect_ci q1_vs_q4_p_value nominally_significant reversed_effect_warning underpowered_warning upload_to_portal sex cases controls genome_build tuning_parameter weights_external_url weights_url phewas_download_url exclusion_download_url last_updated prsweb-phecode165-c3-respiratory-intrathoracic-p-5e-05-mgi-20200608 prsweb-phecode165-c3-respiratory-intrathoracic-p-5e-05-mgi-20200608 PRSWEB_PHECODE165_C3-RESPIRATORY-INTRATHORACIC_P_5e-05_MGI_20200608 P_5e-05 PRSWEB_PHECODE165_C3-RESPIRATORY-INTRATHORACIC_P_5e-05_MGI_20200608 165 Malignant neoplasm of respiratory system and intrathoracic organs Binary GWAS round 2: Results shared 1st August 2018. Imputed genotypes from HRC plus UK10K & 1000 Genomes reference panels as released by UK Biobank in March 2018. MGI Michigan Genomics Initiative Fixed threshold (5e-05) UKB GWAS (FINNGEN) UKB_GWAS https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761 136 0.14 0.00145626 0.0827 0.515 0.489-0.541 OR 0.504 0.14-1.82 0.504 0.14-1.82 0.46 0.177-1.19 0.46 0.177-1.19 1.02 0.667-1.57 1.02 0.667-1.57 1.16 0.86-1.56 1.16 0.86-1.56 1.27 1.03-1.56 1.27 1.03-1.56 1.14 0.869-1.49 0.346 0.967 0.732-1.28 0.817 1.3 1-1.69 0.0503 False False False False Both 475 4743 GRCh37/hg19 P<=5e-05 2020-06-08 prsweb-phecode165-ukbb-saige-hrc-x165-p-5e-05-mgi-20200608 prsweb-phecode165-ukbb-saige-hrc-x165-p-5e-05-mgi-20200608 PRSWEB_PHECODE165_UKBB-SAIGE-HRC-X165_P_5e-05_MGI_20200608 P_5e-05 PRSWEB_PHECODE165_UKBB-SAIGE-HRC-X165_P_5e-05_MGI_20200608 165 Cancer within the respiratory system Binary ICD9 and ICD10 based PheWAS codes MGI Michigan Genomics Initiative Fixed threshold (5e-05) UKB GWAS (PheCode) UKB_GWAS https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761 103 0.32 4.11883e-05 0.0827 0.505 0.479-0.532 OR 1.74 0.83-3.65 1.74 0.83-3.65 1.52 0.865-2.66 1.52 0.865-2.66 1.2 0.804-1.79 1.2 0.804-1.79 1.18 0.881-1.59 1.18 0.881-1.59 1.09 0.879-1.35 1.09 0.879-1.35 1.01 0.774-1.31 0.949 0.94 0.717-1.23 0.654 1.07 0.819-1.39 0.637 False False False False Both 475 4743 GRCh37/hg19 P<=5e-05 2020-06-08 prsweb-phecode165-c3-respiratory-intrathoracic-p-5e-06-mgi-20200608 prsweb-phecode165-c3-respiratory-intrathoracic-p-5e-06-mgi-20200608 PRSWEB_PHECODE165_C3-RESPIRATORY-INTRATHORACIC_P_5e-06_MGI_20200608 P_5e-06 PRSWEB_PHECODE165_C3-RESPIRATORY-INTRATHORACIC_P_5e-06_MGI_20200608 165 Malignant neoplasm of respiratory system and intrathoracic organs Binary GWAS round 2: Results shared 1st August 2018. Imputed genotypes from HRC plus UK10K & 1000 Genomes reference panels as released by UK Biobank in March 2018. MGI Michigan Genomics Initiative Fixed threshold (5e-06) UKB GWAS (FINNGEN) UKB_GWAS https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761 27 0.72 2.25885e-05 0.0827 0.492 0.465-0.518 OR 0.511 0.141-1.85 0.511 0.141-1.85 0.671 0.301-1.5 0.671 0.301-1.5 0.852 0.537-1.35 0.852 0.537-1.35 1.02 0.747-1.39 1.02 0.747-1.39 0.951 0.763-1.18 0.951 0.763-1.18 0.85 0.648-1.12 0.242 1.1 0.854-1.43 0.452 0.933 0.715-1.22 0.61 False False False False Both 475 4743 GRCh37/hg19 P<=5e-06 2020-06-08 prsweb-phecode165-ukbb-saige-hrc-x165-p-5e-06-mgi-20200608 prsweb-phecode165-ukbb-saige-hrc-x165-p-5e-06-mgi-20200608 PRSWEB_PHECODE165_UKBB-SAIGE-HRC-X165_P_5e-06_MGI_20200608 P_5e-06 PRSWEB_PHECODE165_UKBB-SAIGE-HRC-X165_P_5e-06_MGI_20200608 165 Cancer within the respiratory system Binary ICD9 and ICD10 based PheWAS codes MGI Michigan Genomics Initiative Fixed threshold (5e-06) UKB GWAS (PheCode) UKB_GWAS https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761 18 0.34 1.5221e-05 0.0827 0.503 0.477-0.532 OR 1.12 0.46-2.75 1.12 0.46-2.75 0.888 0.437-1.81 0.888 0.437-1.81 1.12 0.74-1.69 1.12 0.74-1.69 1.21 0.904-1.62 1.21 0.904-1.62 1.11 0.896-1.37 1.11 0.896-1.37 1.18 0.905-1.54 0.22 1.01 0.764-1.33 0.959 1.17 0.897-1.53 0.247 False False False False Both 475 4743 GRCh37/hg19 P<=5e-06 2020-06-08 prsweb-phecode165-c3-respiratory-intrathoracic-p-5e-07-mgi-20200608 prsweb-phecode165-c3-respiratory-intrathoracic-p-5e-07-mgi-20200608 PRSWEB_PHECODE165_C3-RESPIRATORY-INTRATHORACIC_P_5e-07_MGI_20200608 P_5e-07 PRSWEB_PHECODE165_C3-RESPIRATORY-INTRATHORACIC_P_5e-07_MGI_20200608 165 Malignant neoplasm of respiratory system and intrathoracic organs Binary GWAS round 2: Results shared 1st August 2018. Imputed genotypes from HRC plus UK10K & 1000 Genomes reference panels as released by UK Biobank in March 2018. MGI Michigan Genomics Initiative Fixed threshold (5e-07) UKB GWAS (FINNGEN) UKB_GWAS https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761 9 0.6 0.000624929 0.0827 0.48 0.454-0.505 OR 1.11 0.453-2.71 1.11 0.453-2.71 1.29 0.706-2.34 1.29 0.706-2.34 1.14 0.761-1.72 1.14 0.761-1.72 1.04 0.762-1.41 1.04 0.762-1.41 1.09 0.883-1.35 1.09 0.883-1.35 1.08 0.829-1.4 0.579 0.914 0.692-1.21 0.526 1.1 0.844-1.43 0.485 False False False False Both 475 4743 GRCh37/hg19 P<=5e-07 2020-06-08 prsweb-phecode165-ukbb-saige-hrc-x165-p-5e-07-mgi-20200608 prsweb-phecode165-ukbb-saige-hrc-x165-p-5e-07-mgi-20200608 PRSWEB_PHECODE165_UKBB-SAIGE-HRC-X165_P_5e-07_MGI_20200608 P_5e-07 PRSWEB_PHECODE165_UKBB-SAIGE-HRC-X165_P_5e-07_MGI_20200608 165 Cancer within the respiratory system Binary ICD9 and ICD10 based PheWAS codes MGI Michigan Genomics Initiative Fixed threshold (5e-07) UKB GWAS (PheCode) UKB_GWAS https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761 5 0.44 4.22101e-05 0.0827 0.505 0.477-0.532 OR 1.37 0.595-3.14 1.37 0.595-3.14 1.11 0.579-2.11 1.11 0.579-2.11 1.2 0.807-1.8 1.2 0.807-1.8 1.28 0.961-1.71 1.28 0.961-1.71 1.11 0.896-1.37 1.11 0.896-1.37 1.11 0.851-1.45 0.443 0.962 0.731-1.27 0.781 1.13 0.87-1.48 0.351 False False False False Both 475 4743 GRCh37/hg19 P<=5e-07 2020-06-08 prsweb-phecode165-c3-mesothelioma-pt-mgi-20200608 prsweb-phecode165-c3-mesothelioma-pt-mgi-20200608 PRSWEB_PHECODE165_C3-MESOTHELIOMA_PT_MGI_20200608 P&T PRSWEB_PHECODE165_C3-MESOTHELIOMA_PT_MGI_20200608 165 Mesothelioma Binary GWAS round 2: Results shared 1st August 2018. Imputed genotypes from HRC plus UK10K & 1000 Genomes reference panels as released by UK Biobank in March 2018. MGI Michigan Genomics Initiative P&T UKB GWAS (FINNGEN) UKB_GWAS https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761 18 0.98 0.00054416 0.0827 0.497 0.47-0.526 OR 1.34 0.582-3.07 1.34 0.582-3.07 0.88 0.433-1.79 0.88 0.433-1.79 0.974 0.631-1.5 0.974 0.631-1.5 1.18 0.879-1.59 1.18 0.879-1.59 1.07 0.866-1.33 1.07 0.866-1.33 1.11 0.852-1.45 0.432 1.02 0.775-1.33 0.907 1.11 0.849-1.45 0.451 False False False False Both 475 4743 GRCh37/hg19 P<=1e-05 2020-06-08 prsweb-phecode165-c3-respiratory-intrathoracic-pt-mgi-20200608 prsweb-phecode165-c3-respiratory-intrathoracic-pt-mgi-20200608 PRSWEB_PHECODE165_C3-RESPIRATORY-INTRATHORACIC_PT_MGI_20200608 P&T PRSWEB_PHECODE165_C3-RESPIRATORY-INTRATHORACIC_PT_MGI_20200608 165 Malignant neoplasm of respiratory system and intrathoracic organs Binary GWAS round 2: Results shared 1st August 2018. Imputed genotypes from HRC plus UK10K & 1000 Genomes reference panels as released by UK Biobank in March 2018. MGI Michigan Genomics Initiative P&T UKB GWAS (FINNGEN) UKB_GWAS https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761 136 0.14 0.00145626 0.0827 0.515 0.489-0.541 OR 0.504 0.14-1.82 0.504 0.14-1.82 0.46 0.177-1.19 0.46 0.177-1.19 1.02 0.667-1.57 1.02 0.667-1.57 1.16 0.86-1.56 1.16 0.86-1.56 1.27 1.03-1.56 1.27 1.03-1.56 1.14 0.869-1.49 0.346 0.967 0.732-1.28 0.817 1.3 1-1.69 0.0503 False False False False Both 475 4743 GRCh37/hg19 P<=5e-05 2020-06-08 prsweb-phecode165-ukbb-saige-hrc-x165-pt-mgi-20200608 prsweb-phecode165-ukbb-saige-hrc-x165-pt-mgi-20200608 PRSWEB_PHECODE165_UKBB-SAIGE-HRC-X165_PT_MGI_20200608 P&T PRSWEB_PHECODE165_UKBB-SAIGE-HRC-X165_PT_MGI_20200608 165 Cancer within the respiratory system Binary ICD9 and ICD10 based PheWAS codes MGI Michigan Genomics Initiative P&T UKB GWAS (PheCode) UKB_GWAS https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761 46 0.21 0.000174384 0.0827 0.508 0.482-0.537 OR 1.34 0.584-3.08 1.34 0.584-3.08 1.09 0.573-2.09 1.09 0.573-2.09 1.02 0.667-1.57 1.02 0.667-1.57 1.25 0.939-1.67 1.25 0.939-1.67 1.05 0.848-1.3 1.05 0.848-1.3 1.07 0.82-1.4 0.616 1.03 0.788-1.35 0.821 1.09 0.834-1.42 0.536 False False False False Both 475 4743 GRCh37/hg19 P<=2e-05 2020-06-08 prsweb-phecode165-c3-mesothelioma-prs-cs-mgi-20200608 prsweb-phecode165-c3-mesothelioma-prs-cs-mgi-20200608 PRSWEB_PHECODE165_C3-MESOTHELIOMA_PRS-CS_MGI_20200608 PRS-CS PRSWEB_PHECODE165_C3-MESOTHELIOMA_PRS-CS_MGI_20200608 165 Mesothelioma Binary GWAS round 2: Results shared 1st August 2018. Imputed genotypes from HRC plus UK10K & 1000 Genomes reference panels as released by UK Biobank in March 2018. MGI Michigan Genomics Initiative PRS-CS UKB GWAS (FINNGEN) UKB_GWAS https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761 938343 0.16 0.00111442 0.0827 0.518 0.49-0.546 OR 1.14 0.466-2.79 1.14 0.466-2.79 1.21 0.653-2.26 1.21 0.653-2.26 1.21 0.813-1.81 1.21 0.813-1.81 1.19 0.887-1.6 1.19 0.887-1.6 1.12 0.902-1.38 1.12 0.902-1.38 0.944 0.718-1.24 0.678 1.08 0.827-1.41 0.579 1.13 0.871-1.48 0.351 False False False False Both 475 4743 GRCh37/hg19 auto 2020-06-08 prsweb-phecode165-c3-respiratory-intrathoracic-prs-cs-mgi-20200608 prsweb-phecode165-c3-respiratory-intrathoracic-prs-cs-mgi-20200608 PRSWEB_PHECODE165_C3-RESPIRATORY-INTRATHORACIC_PRS-CS_MGI_20200608 PRS-CS PRSWEB_PHECODE165_C3-RESPIRATORY-INTRATHORACIC_PRS-CS_MGI_20200608 165 Malignant neoplasm of respiratory system and intrathoracic organs Binary GWAS round 2: Results shared 1st August 2018. Imputed genotypes from HRC plus UK10K & 1000 Genomes reference panels as released by UK Biobank in March 2018. MGI Michigan Genomics Initiative PRS-CS UKB GWAS (FINNGEN) UKB_GWAS https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761 1110227 0.19 0.000189358 0.0827 0.52 0.493-0.547 OR 1.78 0.848-3.73 1.78 0.848-3.73 1.44 0.805-2.57 1.44 0.805-2.57 0.766 0.473-1.24 0.766 0.473-1.24 0.817 0.582-1.15 0.817 0.582-1.15 1.01 0.812-1.26 1.01 0.812-1.26 1.07 0.813-1.42 0.617 1.36 1.05-1.78 0.0218 1.15 0.876-1.52 0.308 False False False False Both 475 4743 GRCh37/hg19 auto 2020-06-08 prsweb-phecode165-c45-prs-cs-mgi-20200608 prsweb-phecode165-c45-prs-cs-mgi-20200608 PRSWEB_PHECODE165_C45_PRS-CS_MGI_20200608 PRS-CS PRSWEB_PHECODE165_C45_PRS-CS_MGI_20200608 165 Diagnoses - main ICD10: C45 Mesothelioma Binary GWAS round 2: Results shared 1st August 2018. Imputed genotypes from HRC plus UK10K & 1000 Genomes reference panels as released by UK Biobank in March 2018. MGI Michigan Genomics Initiative PRS-CS UKB GWAS (ICD10) UKB_GWAS https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761 934591 0.35 0.00115817 0.0827 0.511 0.485-0.54 OR 1.56 0.713-3.4 1.56 0.713-3.4 1.64 0.95-2.84 1.64 0.95-2.84 0.986 0.639-1.52 0.986 0.639-1.52 1.12 0.826-1.51 1.12 0.826-1.51 0.996 0.801-1.24 0.996 0.801-1.24 1.18 0.898-1.55 0.237 1.25 0.958-1.64 0.1 1.14 0.867-1.5 0.344 False False False False Both 475 4743 GRCh37/hg19 auto 2020-06-08 prsweb-phecode165-ukbb-saige-hrc-x165-prs-cs-mgi-20200608 prsweb-phecode165-ukbb-saige-hrc-x165-prs-cs-mgi-20200608 PRSWEB_PHECODE165_UKBB-SAIGE-HRC-X165_PRS-CS_MGI_20200608 PRS-CS PRSWEB_PHECODE165_UKBB-SAIGE-HRC-X165_PRS-CS_MGI_20200608 165 Cancer within the respiratory system Binary ICD9 and ICD10 based PheWAS codes MGI Michigan Genomics Initiative PRS-CS UKB GWAS (PheCode) UKB_GWAS https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761 1119238 0.057 0.00198538 0.0826 0.527 0.499-0.553 OR 0.718 0.24-2.15 0.718 0.24-2.15 0.889 0.437-1.81 0.889 0.437-1.81 1.21 0.813-1.81 1.21 0.813-1.81 1.27 0.948-1.69 1.27 0.948-1.69 1.33 1.09-1.64 1.33 1.09-1.64 1.12 0.851-1.47 0.421 1.01 0.767-1.34 0.917 1.38 1.06-1.79 0.017 False False False False Both 475 4743 GRCh37/hg19 auto 2020-06-08 prsweb-phecode165-c3-mesothelioma-lassosum-mgi-20200608 prsweb-phecode165-c3-mesothelioma-lassosum-mgi-20200608 PRSWEB_PHECODE165_C3-MESOTHELIOMA_LASSOSUM_MGI_20200608 Lassosum PRSWEB_PHECODE165_C3-MESOTHELIOMA_LASSOSUM_MGI_20200608 165 Mesothelioma Binary GWAS round 2: Results shared 1st August 2018. Imputed genotypes from HRC plus UK10K & 1000 Genomes reference panels as released by UK Biobank in March 2018. MGI Michigan Genomics Initiative lassosum UKB GWAS (FINNGEN) UKB_GWAS https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761 3382118 0.14 0.00210676 0.0827 0.519 0.493-0.547 OR 1.14 0.466-2.79 1.14 0.466-2.79 0.992 0.505-1.95 0.992 0.505-1.95 1.12 0.74-1.69 1.12 0.74-1.69 1.24 0.928-1.66 1.24 0.928-1.66 1.1 0.892-1.37 1.1 0.892-1.37 1.01 0.767-1.32 0.953 1.11 0.853-1.46 0.426 1.16 0.887-1.51 0.282 False False False False Both 475 4743 GRCh37/hg19 s=1;Lambda=0.001 2020-06-08 prsweb-phecode165-c3-respiratory-intrathoracic-lassosum-mgi-20200608 prsweb-phecode165-c3-respiratory-intrathoracic-lassosum-mgi-20200608 PRSWEB_PHECODE165_C3-RESPIRATORY-INTRATHORACIC_LASSOSUM_MGI_20200608 Lassosum PRSWEB_PHECODE165_C3-RESPIRATORY-INTRATHORACIC_LASSOSUM_MGI_20200608 165 Malignant neoplasm of respiratory system and intrathoracic organs Binary GWAS round 2: Results shared 1st August 2018. Imputed genotypes from HRC plus UK10K & 1000 Genomes reference panels as released by UK Biobank in March 2018. MGI Michigan Genomics Initiative lassosum UKB GWAS (FINNGEN) UKB_GWAS https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761 1898 0.12 0.00116527 0.0827 0.523 0.495-0.549 OR 0.927 0.349-2.47 0.927 0.349-2.47 0.895 0.44-1.82 0.895 0.44-1.82 1.07 0.705-1.63 1.07 0.705-1.63 1.02 0.746-1.39 1.02 0.746-1.39 1.08 0.87-1.33 1.08 0.87-1.33 1.11 0.842-1.47 0.452 1.34 1.03-1.75 0.0321 1.24 0.946-1.63 0.119 False False False False Both 475 4743 GRCh37/hg19 s=0.2;Lambda=0.03793 2020-06-08 prsweb-phecode165-c45-lassosum-mgi-20200608 prsweb-phecode165-c45-lassosum-mgi-20200608 PRSWEB_PHECODE165_C45_LASSOSUM_MGI_20200608 Lassosum PRSWEB_PHECODE165_C45_LASSOSUM_MGI_20200608 165 Diagnoses - main ICD10: C45 Mesothelioma Binary GWAS round 2: Results shared 1st August 2018. Imputed genotypes from HRC plus UK10K & 1000 Genomes reference panels as released by UK Biobank in March 2018. MGI Michigan Genomics Initiative lassosum UKB GWAS (ICD10) UKB_GWAS https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761 3360952 0.11 0.00197781 0.0827 0.52 0.495-0.548 OR 1.13 0.463-2.77 1.13 0.463-2.77 0.995 0.506-1.96 0.995 0.506-1.96 0.98 0.635-1.51 0.98 0.635-1.51 1.23 0.92-1.65 1.23 0.92-1.65 1.26 1.02-1.55 1.26 1.02-1.55 1.14 0.866-1.5 0.354 1.09 0.827-1.44 0.535 1.36 1.04-1.78 0.0233 False False False False Both 475 4743 GRCh37/hg19 s=1;Lambda=0.001 2020-06-08 prsweb-phecode165-ukbb-saige-hrc-x165-lassosum-mgi-20200608 prsweb-phecode165-ukbb-saige-hrc-x165-lassosum-mgi-20200608 PRSWEB_PHECODE165_UKBB-SAIGE-HRC-X165_LASSOSUM_MGI_20200608 Lassosum PRSWEB_PHECODE165_UKBB-SAIGE-HRC-X165_LASSOSUM_MGI_20200608 165 Cancer within the respiratory system Binary ICD9 and ICD10 based PheWAS codes MGI Michigan Genomics Initiative lassosum UKB GWAS (PheCode) UKB_GWAS https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761 879334 0.033 0.00187058 0.0826 0.53 0.502-0.557 OR 2.22 1.12-4.37 2.22 1.12-4.37 1.65 0.956-2.86 1.65 0.956-2.86 1.3 0.879-1.92 1.3 0.879-1.92 1.14 0.848-1.54 1.14 0.848-1.54 1.2 0.97-1.48 1.2 0.97-1.48 1.06 0.802-1.4 0.682 1.23 0.934-1.61 0.142 1.3 0.992-1.69 0.0569 True False False True Both 475 4743 GRCh37/hg19 s=1;Lambda=0.01438 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000387/ScoringFiles/ https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000387/ScoringFiles/ /larsf/prsweb-data/cancerprsweb/releases/cancerprsweb_20200608/phewas/PRSWEB_PHECODE165_UKBB-SAIGE-HRC-X165_LASSOSUM_MGI_20200608/all.tsv /larsf/prsweb-data/cancerprsweb/releases/cancerprsweb_20200608/phewas/PRSWEB_PHECODE165_UKBB-SAIGE-HRC-X165_LASSOSUM_MGI_20200608/exclusion.tsv 2020-06-08