prs_id	slug	legacy_id	legacy_model	prswebprefix	trait_code	trait_name	trait_type	description	cohort	cohort_label	method	gwas_source	reference_label	reference_url	snp_count	p_value	pseudo_r2	brier_score	mse	aauc	aauc_ci	effect_metric	top_effect_1	top_effect_1_ci	top_or_1	top_or_1_ci	top_effect_2	top_effect_2_ci	top_or_2	top_or_2_ci	top_effect_5	top_effect_5_ci	top_or_5	top_or_5_ci	top_effect_10	top_effect_10_ci	top_or_10	top_or_10_ci	top_effect_25	top_effect_25_ci	top_or_25	top_or_25_ci	q1_vs_q2_effect	q1_vs_q2_effect_ci	q1_vs_q2_p_value	q1_vs_q3_effect	q1_vs_q3_effect_ci	q1_vs_q3_p_value	q1_vs_q4_effect	q1_vs_q4_effect_ci	q1_vs_q4_p_value	nominally_significant	reversed_effect_warning	underpowered_warning	upload_to_portal	sex	cases	controls	genome_build	tuning_parameter	weights_external_url	weights_url	phewas_download_url	exclusion_download_url	last_updated
prsweb-phecode172-1-20001-1059-p-5e-05-mgi-20200608	prsweb-phecode172-1-20001-1059-p-5e-05-mgi-20200608	PRSWEB_PHECODE172.1_20001-1059_P_5e-05_MGI_20200608	P_5e-05	PRSWEB_PHECODE172.1_20001-1059_P_5e-05_MGI_20200608	172.1	Cancer code, self-reported: malignant melanoma	Binary	GWAS round 2: Results shared 1st August 2018. Imputed genotypes from HRC plus UK10K & 1000 Genomes reference panels as released by UK Biobank in March 2018.	MGI	Michigan Genomics Initiative	Fixed threshold (5e-05)	UKB GWAS (PHESANT)	UKB_GWAS	https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761	129	6e-18	0.00792626	0.0962		0.565	0.549-0.582	OR	1.61	1.01-2.59	1.61	1.01-2.59	1.63	1.16-2.29	1.63	1.16-2.29	1.69	1.36-2.11	1.69	1.36-2.11	1.9	1.63-2.23	1.9	1.63-2.23	1.58	1.4-1.79	1.58	1.4-1.79	1.23	1.03-1.47	0.0225	1.4	1.17-1.67	0.000165	1.91	1.61-2.25	2.33e-14	True	False	False	False	Both	1325	10649	GRCh37/hg19	P<=5e-05					2020-06-08
prsweb-phecode172-1-c3-melanoma-skin-p-5e-05-mgi-20200608	prsweb-phecode172-1-c3-melanoma-skin-p-5e-05-mgi-20200608	PRSWEB_PHECODE172.1_C3-MELANOMA-SKIN_P_5e-05_MGI_20200608	P_5e-05	PRSWEB_PHECODE172.1_C3-MELANOMA-SKIN_P_5e-05_MGI_20200608	172.1	Malignant melanoma of skin	Binary	GWAS round 2: Results shared 1st August 2018. Imputed genotypes from HRC plus UK10K & 1000 Genomes reference panels as released by UK Biobank in March 2018.	MGI	Michigan Genomics Initiative	Fixed threshold (5e-05)	UKB GWAS (FINNGEN)	UKB_GWAS	https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761	153	2.2e-25	0.0102907	0.0959		0.577	0.562-0.593	OR	2.4	1.59-3.63	2.4	1.59-3.63	2.33	1.73-3.14	2.33	1.73-3.14	2	1.63-2.46	2	1.63-2.46	1.77	1.51-2.08	1.77	1.51-2.08	1.73	1.53-1.95	1.73	1.53-1.95	1.21	1.01-1.45	0.0397	1.46	1.22-1.74	3.05e-05	2.09	1.77-2.48	4.09e-18	True	False	False	False	Both	1325	10649	GRCh37/hg19	P<=5e-05					2020-06-08
prsweb-phecode172-1-c43-p-5e-05-mgi-20200608	prsweb-phecode172-1-c43-p-5e-05-mgi-20200608	PRSWEB_PHECODE172.1_C43_P_5e-05_MGI_20200608	P_5e-05	PRSWEB_PHECODE172.1_C43_P_5e-05_MGI_20200608	172.1	Diagnoses - main ICD10: C43 Malignant melanoma of skin	Binary	GWAS round 2: Results shared 1st August 2018. Imputed genotypes from HRC plus UK10K & 1000 Genomes reference panels as released by UK Biobank in March 2018.	MGI	Michigan Genomics Initiative	Fixed threshold (5e-05)	UKB GWAS (ICD10)	UKB_GWAS	https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761	164	5.1e-17	0.00751794	0.0963		0.566	0.55-0.583	OR	1.66	1.04-2.66	1.66	1.04-2.66	1.87	1.35-2.57	1.87	1.35-2.57	1.65	1.33-2.06	1.65	1.33-2.06	1.53	1.3-1.81	1.53	1.3-1.81	1.5	1.33-1.7	1.5	1.33-1.7	1.27	1.06-1.52	0.00878	1.49	1.25-1.77	7.3e-06	1.88	1.59-2.22	2.05e-13	True	False	False	False	Both	1325	10649	GRCh37/hg19	P<=5e-05					2020-06-08
prsweb-phecode172-1-d03-p-5e-05-mgi-20200608	prsweb-phecode172-1-d03-p-5e-05-mgi-20200608	PRSWEB_PHECODE172.1_D03_P_5e-05_MGI_20200608	P_5e-05	PRSWEB_PHECODE172.1_D03_P_5e-05_MGI_20200608	172.1	Diagnoses - main ICD10: D03 Melanoma in situ	Binary	GWAS round 2: Results shared 1st August 2018. Imputed genotypes from HRC plus UK10K & 1000 Genomes reference panels as released by UK Biobank in March 2018.	MGI	Michigan Genomics Initiative	Fixed threshold (5e-05)	UKB GWAS (ICD10)	UKB_GWAS	https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761	95	0.65	0.000227263	0.0969		0.498	0.482-0.516	OR	0.87	0.47-1.61	0.87	0.47-1.61	1.14	0.767-1.68	1.14	0.767-1.68	1.16	0.9-1.48	1.16	0.9-1.48	1.07	0.884-1.29	1.07	0.884-1.29	0.987	0.864-1.13	0.987	0.864-1.13	1.02	0.871-1.2	0.771	1.02	0.871-1.2	0.774	1	0.851-1.18	0.979	False	False	False	False	Both	1325	10649	GRCh37/hg19	P<=5e-05					2020-06-08
prsweb-phecode172-1-gwas-catalog-r2019-05-03-x172-1-p-5e-05-mgi-20200608	prsweb-phecode172-1-gwas-catalog-r2019-05-03-x172-1-p-5e-05-mgi-20200608	PRSWEB_PHECODE172.1_GWAS-Catalog-r2019-05-03-X172.1_P_5e-05_MGI_20200608	P_5e-05	PRSWEB_PHECODE172.1_GWAS-Catalog-r2019-05-03-X172.1_P_5e-05_MGI_20200608	172.1	Melanoma;Cutaneous malignant melanoma	Binary	33 unique SNPs	MGI	Michigan Genomics Initiative	Fixed threshold (5e-05)	GWAS Catalog (2019-05-03)	18488026;19578364;21983785;21983787;23455637;26237428;28212542	https://www.ncbi.nlm.nih.gov/pubmed/?term=18488026+19578364+21983785+21983787+23455637+26237428+28212542	29	2.4e-39	0.0286498	0.0954		0.608	0.592-0.623	OR	2.93	2-4.3	2.93	2-4.3	2.8	2.11-3.7	2.8	2.11-3.7	1.94	1.57-2.38	1.94	1.57-2.38	1.86	1.59-2.18	1.86	1.59-2.18	1.89	1.67-2.13	1.89	1.67-2.13	1.34	1.1-1.62	0.00342	1.85	1.54-2.22	4.13e-11	2.65	2.23-3.16	1.12e-27	True	False	False	False	Both	1325	10649	GRCh37/hg19	P<=5e-05					2020-06-08
prsweb-phecode172-1-melanoma-ransohoff-p-5e-05-mgi-20200608	prsweb-phecode172-1-melanoma-ransohoff-p-5e-05-mgi-20200608	PRSWEB_PHECODE172.1_Melanoma-Ransohoff_P_5e-05_MGI_20200608	P_5e-05	PRSWEB_PHECODE172.1_Melanoma-Ransohoff_P_5e-05_MGI_20200608	172.1	Melanomas of skin, dx or hx	Binary	known and novel	MGI	Michigan Genomics Initiative	Fixed threshold (5e-05)	Ransohoff KJ et al. 2017	28212542	https://www.ncbi.nlm.nih.gov/pubmed/?term=28212542	20	1.2e-34	0.0294901	0.0955		0.601	0.585-0.617	OR	2.54	1.7-3.8	2.54	1.7-3.8	2.78	2.1-3.69	2.78	2.1-3.69	2.16	1.77-2.64	2.16	1.77-2.64	1.88	1.6-2.2	1.88	1.6-2.2	1.61	1.43-1.82	1.61	1.43-1.82	1.24	1.02-1.51	0.0291	2.04	1.71-2.44	3.81e-15	2.34	1.97-2.8	2.66e-21	True	False	False	False	Both	1325	10649	GRCh37/hg19	P<=5e-05					2020-06-08
prsweb-phecode172-1-ukbb-saige-hrc-x172-1-p-5e-05-mgi-20200608	prsweb-phecode172-1-ukbb-saige-hrc-x172-1-p-5e-05-mgi-20200608	PRSWEB_PHECODE172.1_UKBB-SAIGE-HRC-X172.1_P_5e-05_MGI_20200608	P_5e-05	PRSWEB_PHECODE172.1_UKBB-SAIGE-HRC-X172.1_P_5e-05_MGI_20200608	172.1	Melanomas of skin, dx or hx	Binary	ICD9 and ICD10 based PheWAS codes	MGI	Michigan Genomics Initiative	Fixed threshold (5e-05)	UKB GWAS (PheCode)	UKB_GWAS	https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761	138	3.9e-28	0.0116317	0.0959		0.586	0.571-0.602	OR	2.14	1.4-3.26	2.14	1.4-3.26	1.94	1.41-2.66	1.94	1.41-2.66	1.65	1.33-2.06	1.65	1.33-2.06	1.89	1.61-2.21	1.89	1.61-2.21	1.68	1.49-1.9	1.68	1.49-1.9	1.37	1.14-1.65	0.000972	1.71	1.43-2.05	4.39e-09	2.26	1.9-2.68	1.36e-20	True	False	False	False	Both	1325	10649	GRCh37/hg19	P<=5e-05					2020-06-08
prsweb-phecode172-1-20001-1059-p-5e-06-mgi-20200608	prsweb-phecode172-1-20001-1059-p-5e-06-mgi-20200608	PRSWEB_PHECODE172.1_20001-1059_P_5e-06_MGI_20200608	P_5e-06	PRSWEB_PHECODE172.1_20001-1059_P_5e-06_MGI_20200608	172.1	Cancer code, self-reported: malignant melanoma	Binary	GWAS round 2: Results shared 1st August 2018. Imputed genotypes from HRC plus UK10K & 1000 Genomes reference panels as released by UK Biobank in March 2018.	MGI	Michigan Genomics Initiative	Fixed threshold (5e-06)	UKB GWAS (PHESANT)	UKB_GWAS	https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761	29	6.7e-30	0.0132182	0.0958		0.579	0.564-0.596	OR	1.81	1.16-2.84	1.81	1.16-2.84	2.15	1.58-2.92	2.15	1.58-2.92	2.31	1.9-2.82	2.31	1.9-2.82	2.08	1.78-2.42	2.08	1.78-2.42	1.73	1.54-1.96	1.73	1.54-1.96	1.25	1.04-1.51	0.018	1.61	1.34-1.92	1.66e-07	2.23	1.88-2.64	1.44e-20	True	False	False	False	Both	1325	10649	GRCh37/hg19	P<=5e-06					2020-06-08
prsweb-phecode172-1-c3-melanoma-skin-p-5e-06-mgi-20200608	prsweb-phecode172-1-c3-melanoma-skin-p-5e-06-mgi-20200608	PRSWEB_PHECODE172.1_C3-MELANOMA-SKIN_P_5e-06_MGI_20200608	P_5e-06	PRSWEB_PHECODE172.1_C3-MELANOMA-SKIN_P_5e-06_MGI_20200608	172.1	Malignant melanoma of skin	Binary	GWAS round 2: Results shared 1st August 2018. Imputed genotypes from HRC plus UK10K & 1000 Genomes reference panels as released by UK Biobank in March 2018.	MGI	Michigan Genomics Initiative	Fixed threshold (5e-06)	UKB GWAS (FINNGEN)	UKB_GWAS	https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761	42	7.9e-32	0.0156177	0.0957		0.584	0.568-0.6	OR	2.49	1.66-3.71	2.49	1.66-3.71	2.61	1.96-3.47	2.61	1.96-3.47	2.08	1.7-2.56	2.08	1.7-2.56	2.06	1.77-2.41	2.06	1.77-2.41	1.8	1.59-2.03	1.8	1.59-2.03	1.21	1.01-1.46	0.0426	1.54	1.29-1.84	1.86e-06	2.26	1.91-2.67	2.14e-21	True	False	False	False	Both	1325	10649	GRCh37/hg19	P<=5e-06					2020-06-08
prsweb-phecode172-1-c43-p-5e-06-mgi-20200608	prsweb-phecode172-1-c43-p-5e-06-mgi-20200608	PRSWEB_PHECODE172.1_C43_P_5e-06_MGI_20200608	P_5e-06	PRSWEB_PHECODE172.1_C43_P_5e-06_MGI_20200608	172.1	Diagnoses - main ICD10: C43 Malignant melanoma of skin	Binary	GWAS round 2: Results shared 1st August 2018. Imputed genotypes from HRC plus UK10K & 1000 Genomes reference panels as released by UK Biobank in March 2018.	MGI	Michigan Genomics Initiative	Fixed threshold (5e-06)	UKB GWAS (ICD10)	UKB_GWAS	https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761	37	5.3e-32	0.0122799	0.0957		0.587	0.571-0.604	OR	1.84	1.17-2.9	1.84	1.17-2.9	2.25	1.67-3.03	2.25	1.67-3.03	2	1.63-2.46	2	1.63-2.46	2.19	1.88-2.55	2.19	1.88-2.55	1.8	1.6-2.03	1.8	1.6-2.03	1.17	0.975-1.41	0.0912	1.56	1.31-1.86	8.19e-07	2.23	1.89-2.64	4.84e-21	True	False	False	False	Both	1325	10649	GRCh37/hg19	P<=5e-06					2020-06-08
prsweb-phecode172-1-gwas-catalog-r2019-05-03-x172-1-p-5e-06-mgi-20200608	prsweb-phecode172-1-gwas-catalog-r2019-05-03-x172-1-p-5e-06-mgi-20200608	PRSWEB_PHECODE172.1_GWAS-Catalog-r2019-05-03-X172.1_P_5e-06_MGI_20200608	P_5e-06	PRSWEB_PHECODE172.1_GWAS-Catalog-r2019-05-03-X172.1_P_5e-06_MGI_20200608	172.1	Melanoma;Cutaneous malignant melanoma	Binary	33 unique SNPs	MGI	Michigan Genomics Initiative	Fixed threshold (5e-06)	GWAS Catalog (2019-05-03)	18488026;19578364;21983785;21983787;23455637;26237428;28212542	https://www.ncbi.nlm.nih.gov/pubmed/?term=18488026+19578364+21983785+21983787+23455637+26237428+28212542	29	2.4e-39	0.0286498	0.0954		0.608	0.592-0.623	OR	2.93	2-4.3	2.93	2-4.3	2.8	2.11-3.7	2.8	2.11-3.7	1.94	1.57-2.38	1.94	1.57-2.38	1.86	1.59-2.18	1.86	1.59-2.18	1.89	1.67-2.13	1.89	1.67-2.13	1.34	1.1-1.62	0.00342	1.85	1.54-2.22	4.13e-11	2.65	2.23-3.16	1.12e-27	True	False	False	False	Both	1325	10649	GRCh37/hg19	P<=5e-06					2020-06-08
prsweb-phecode172-1-melanoma-ransohoff-p-5e-06-mgi-20200608	prsweb-phecode172-1-melanoma-ransohoff-p-5e-06-mgi-20200608	PRSWEB_PHECODE172.1_Melanoma-Ransohoff_P_5e-06_MGI_20200608	P_5e-06	PRSWEB_PHECODE172.1_Melanoma-Ransohoff_P_5e-06_MGI_20200608	172.1	Melanomas of skin, dx or hx	Binary	known and novel	MGI	Michigan Genomics Initiative	Fixed threshold (5e-06)	Ransohoff KJ et al. 2017	28212542	https://www.ncbi.nlm.nih.gov/pubmed/?term=28212542	20	1.2e-34	0.0294901	0.0955		0.601	0.585-0.617	OR	2.54	1.7-3.8	2.54	1.7-3.8	2.78	2.1-3.69	2.78	2.1-3.69	2.16	1.77-2.64	2.16	1.77-2.64	1.88	1.6-2.2	1.88	1.6-2.2	1.61	1.43-1.82	1.61	1.43-1.82	1.24	1.02-1.51	0.0291	2.04	1.71-2.44	3.81e-15	2.34	1.97-2.8	2.66e-21	True	False	False	False	Both	1325	10649	GRCh37/hg19	P<=5e-06					2020-06-08
prsweb-phecode172-1-ukbb-saige-hrc-x172-1-p-5e-06-mgi-20200608	prsweb-phecode172-1-ukbb-saige-hrc-x172-1-p-5e-06-mgi-20200608	PRSWEB_PHECODE172.1_UKBB-SAIGE-HRC-X172.1_P_5e-06_MGI_20200608	P_5e-06	PRSWEB_PHECODE172.1_UKBB-SAIGE-HRC-X172.1_P_5e-06_MGI_20200608	172.1	Melanomas of skin, dx or hx	Binary	ICD9 and ICD10 based PheWAS codes	MGI	Michigan Genomics Initiative	Fixed threshold (5e-06)	UKB GWAS (PheCode)	UKB_GWAS	https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761	34	2.1e-37	0.0181253	0.0955		0.596	0.58-0.613	OR	2.21	1.45-3.37	2.21	1.45-3.37	2.43	1.81-3.26	2.43	1.81-3.26	2.2	1.8-2.68	2.2	1.8-2.68	2.14	1.84-2.5	2.14	1.84-2.5	1.99	1.77-2.25	1.99	1.77-2.25	1.37	1.13-1.65	0.00113	1.54	1.28-1.85	4.99e-06	2.6	2.19-3.08	1.12e-27	True	False	False	False	Both	1325	10649	GRCh37/hg19	P<=5e-06					2020-06-08
prsweb-phecode172-1-20001-1059-p-5e-07-mgi-20200608	prsweb-phecode172-1-20001-1059-p-5e-07-mgi-20200608	PRSWEB_PHECODE172.1_20001-1059_P_5e-07_MGI_20200608	P_5e-07	PRSWEB_PHECODE172.1_20001-1059_P_5e-07_MGI_20200608	172.1	Cancer code, self-reported: malignant melanoma	Binary	GWAS round 2: Results shared 1st August 2018. Imputed genotypes from HRC plus UK10K & 1000 Genomes reference panels as released by UK Biobank in March 2018.	MGI	Michigan Genomics Initiative	Fixed threshold (5e-07)	UKB GWAS (PHESANT)	UKB_GWAS	https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761	14	2.1e-33	0.0141906	0.0956		0.58	0.565-0.597	OR	2.48	1.66-3.7	2.48	1.66-3.7	2.36	1.75-3.18	2.36	1.75-3.18	2.29	1.87-2.79	2.29	1.87-2.79	2.07	1.77-2.42	2.07	1.77-2.42	1.81	1.6-2.04	1.81	1.6-2.04	1.33	1.11-1.61	0.0026	1.63	1.36-1.95	1.11e-07	2.39	2.02-2.84	1.7e-23	True	False	False	False	Both	1325	10649	GRCh37/hg19	P<=5e-07					2020-06-08
prsweb-phecode172-1-c3-melanoma-skin-p-5e-07-mgi-20200608	prsweb-phecode172-1-c3-melanoma-skin-p-5e-07-mgi-20200608	PRSWEB_PHECODE172.1_C3-MELANOMA-SKIN_P_5e-07_MGI_20200608	P_5e-07	PRSWEB_PHECODE172.1_C3-MELANOMA-SKIN_P_5e-07_MGI_20200608	172.1	Malignant melanoma of skin	Binary	GWAS round 2: Results shared 1st August 2018. Imputed genotypes from HRC plus UK10K & 1000 Genomes reference panels as released by UK Biobank in March 2018.	MGI	Michigan Genomics Initiative	Fixed threshold (5e-07)	UKB GWAS (FINNGEN)	UKB_GWAS	https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761	22	5.2e-38	0.0163732	0.0954		0.592	0.577-0.608	OR	2.83	1.92-4.18	2.83	1.92-4.18	2.58	1.94-3.44	2.58	1.94-3.44	2.27	1.86-2.76	2.27	1.86-2.76	2.2	1.89-2.56	2.2	1.89-2.56	2.03	1.8-2.29	2.03	1.8-2.29	1.01	0.832-1.22	0.95	1.42	1.19-1.7	8.99e-05	2.32	1.97-2.73	9.1e-24	True	False	False	False	Both	1325	10649	GRCh37/hg19	P<=5e-07					2020-06-08
prsweb-phecode172-1-c43-p-5e-07-mgi-20200608	prsweb-phecode172-1-c43-p-5e-07-mgi-20200608	PRSWEB_PHECODE172.1_C43_P_5e-07_MGI_20200608	P_5e-07	PRSWEB_PHECODE172.1_C43_P_5e-07_MGI_20200608	172.1	Diagnoses - main ICD10: C43 Malignant melanoma of skin	Binary	GWAS round 2: Results shared 1st August 2018. Imputed genotypes from HRC plus UK10K & 1000 Genomes reference panels as released by UK Biobank in March 2018.	MGI	Michigan Genomics Initiative	Fixed threshold (5e-07)	UKB GWAS (ICD10)	UKB_GWAS	https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761	14	5.2e-39	0.0144363	0.0954		0.594	0.579-0.609	OR	2.58	1.73-3.84	2.58	1.73-3.84	2.4	1.78-3.22	2.4	1.78-3.22	2.3	1.88-2.8	2.3	1.88-2.8	2.19	1.88-2.55	2.19	1.88-2.55	1.89	1.67-2.13	1.89	1.67-2.13	1.52	1.26-1.84	1.6e-05	1.81	1.51-2.18	3.7e-10	2.75	2.3-3.28	3.07e-29	True	False	False	False	Both	1325	10649	GRCh37/hg19	P<=5e-07					2020-06-08
prsweb-phecode172-1-gwas-catalog-r2019-05-03-x172-1-p-5e-07-mgi-20200608	prsweb-phecode172-1-gwas-catalog-r2019-05-03-x172-1-p-5e-07-mgi-20200608	PRSWEB_PHECODE172.1_GWAS-Catalog-r2019-05-03-X172.1_P_5e-07_MGI_20200608	P_5e-07	PRSWEB_PHECODE172.1_GWAS-Catalog-r2019-05-03-X172.1_P_5e-07_MGI_20200608	172.1	Melanoma;Cutaneous malignant melanoma	Binary	33 unique SNPs	MGI	Michigan Genomics Initiative	Fixed threshold (5e-07)	GWAS Catalog (2019-05-03)	18488026;19578364;21983785;21983787;23455637;26237428;28212542	https://www.ncbi.nlm.nih.gov/pubmed/?term=18488026+19578364+21983785+21983787+23455637+26237428+28212542	27	4.8e-38	0.0282683	0.0954		0.606	0.589-0.621	OR	2.59	1.74-3.86	2.59	1.74-3.86	2.36	1.76-3.18	2.36	1.76-3.18	2.14	1.75-2.62	2.14	1.75-2.62	1.89	1.62-2.22	1.89	1.62-2.22	1.88	1.67-2.12	1.88	1.67-2.12	1.48	1.22-1.8	7.23e-05	1.87	1.55-2.25	4.74e-11	2.75	2.3-3.29	5.77e-29	True	False	False	False	Both	1325	10649	GRCh37/hg19	P<=5e-07					2020-06-08
prsweb-phecode172-1-melanoma-ransohoff-p-5e-07-mgi-20200608	prsweb-phecode172-1-melanoma-ransohoff-p-5e-07-mgi-20200608	PRSWEB_PHECODE172.1_Melanoma-Ransohoff_P_5e-07_MGI_20200608	P_5e-07	PRSWEB_PHECODE172.1_Melanoma-Ransohoff_P_5e-07_MGI_20200608	172.1	Melanomas of skin, dx or hx	Binary	known and novel	MGI	Michigan Genomics Initiative	Fixed threshold (5e-07)	Ransohoff KJ et al. 2017	28212542	https://www.ncbi.nlm.nih.gov/pubmed/?term=28212542	20	1.2e-34	0.0294901	0.0955		0.601	0.585-0.617	OR	2.54	1.7-3.8	2.54	1.7-3.8	2.78	2.1-3.69	2.78	2.1-3.69	2.16	1.77-2.64	2.16	1.77-2.64	1.88	1.6-2.2	1.88	1.6-2.2	1.61	1.43-1.82	1.61	1.43-1.82	1.24	1.02-1.51	0.0291	2.04	1.71-2.44	3.81e-15	2.34	1.97-2.8	2.66e-21	True	False	False	False	Both	1325	10649	GRCh37/hg19	P<=5e-07					2020-06-08
prsweb-phecode172-1-ukbb-saige-hrc-x172-1-p-5e-07-mgi-20200608	prsweb-phecode172-1-ukbb-saige-hrc-x172-1-p-5e-07-mgi-20200608	PRSWEB_PHECODE172.1_UKBB-SAIGE-HRC-X172.1_P_5e-07_MGI_20200608	P_5e-07	PRSWEB_PHECODE172.1_UKBB-SAIGE-HRC-X172.1_P_5e-07_MGI_20200608	172.1	Melanomas of skin, dx or hx	Binary	ICD9 and ICD10 based PheWAS codes	MGI	Michigan Genomics Initiative	Fixed threshold (5e-07)	UKB GWAS (PheCode)	UKB_GWAS	https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761	19	3.5e-43	0.0187653	0.0952		0.604	0.588-0.62	OR	2.68	1.81-3.98	2.68	1.81-3.98	2.5	1.87-3.35	2.5	1.87-3.35	2.53	2.09-3.06	2.53	2.09-3.06	2.28	1.96-2.65	2.28	1.96-2.65	1.94	1.72-2.19	1.94	1.72-2.19	1.38	1.13-1.67	0.00124	1.82	1.51-2.19	1.88e-10	2.73	2.3-3.26	2.16e-29	True	False	False	False	Both	1325	10649	GRCh37/hg19	P<=5e-07					2020-06-08
prsweb-phecode172-1-20001-1059-p-5e-09-mgi-20200608	prsweb-phecode172-1-20001-1059-p-5e-09-mgi-20200608	PRSWEB_PHECODE172.1_20001-1059_P_5e-09_MGI_20200608	P_5e-09	PRSWEB_PHECODE172.1_20001-1059_P_5e-09_MGI_20200608	172.1	Cancer code, self-reported: malignant melanoma	Binary	GWAS round 2: Results shared 1st August 2018. Imputed genotypes from HRC plus UK10K & 1000 Genomes reference panels as released by UK Biobank in March 2018.	MGI	Michigan Genomics Initiative	Fixed threshold (5e-09)	UKB GWAS (PHESANT)	UKB_GWAS	https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761	9	4.3e-33	0.0132507	0.0957		0.578	0.563-0.595	OR	2.21	1.45-3.35	2.21	1.45-3.35	2.46	1.83-3.3	2.46	1.83-3.3	2.31	1.9-2.82	2.31	1.9-2.82	2.06	1.77-2.41	2.06	1.77-2.41	1.7	1.51-1.92	1.7	1.51-1.92	1.28	1.06-1.54	0.00989	1.67	1.39-1.99	1.82e-08	2.25	1.9-2.67	1.07e-20	True	False	False	False	Both	1325	10649	GRCh37/hg19	P<=5e-09					2020-06-08
prsweb-phecode172-1-c3-melanoma-skin-p-5e-09-mgi-20200608	prsweb-phecode172-1-c3-melanoma-skin-p-5e-09-mgi-20200608	PRSWEB_PHECODE172.1_C3-MELANOMA-SKIN_P_5e-09_MGI_20200608	P_5e-09	PRSWEB_PHECODE172.1_C3-MELANOMA-SKIN_P_5e-09_MGI_20200608	172.1	Malignant melanoma of skin	Binary	GWAS round 2: Results shared 1st August 2018. Imputed genotypes from HRC plus UK10K & 1000 Genomes reference panels as released by UK Biobank in March 2018.	MGI	Michigan Genomics Initiative	Fixed threshold (5e-09)	UKB GWAS (FINNGEN)	UKB_GWAS	https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761	11	1.1e-38	0.0149737	0.0954		0.591	0.575-0.607	OR	2.91	1.99-4.26	2.91	1.99-4.26	3.04	2.31-3.99	3.04	2.31-3.99	2.24	1.84-2.73	2.24	1.84-2.73	2.05	1.76-2.39	2.05	1.76-2.39	1.92	1.71-2.17	1.92	1.71-2.17	1.42	1.17-1.71	0.000273	1.57	1.3-1.88	1.6e-06	2.58	2.17-3.07	3.16e-27	True	False	False	False	Both	1325	10649	GRCh37/hg19	P<=5e-09					2020-06-08
prsweb-phecode172-1-c43-p-5e-09-mgi-20200608	prsweb-phecode172-1-c43-p-5e-09-mgi-20200608	PRSWEB_PHECODE172.1_C43_P_5e-09_MGI_20200608	P_5e-09	PRSWEB_PHECODE172.1_C43_P_5e-09_MGI_20200608	172.1	Diagnoses - main ICD10: C43 Malignant melanoma of skin	Binary	GWAS round 2: Results shared 1st August 2018. Imputed genotypes from HRC plus UK10K & 1000 Genomes reference panels as released by UK Biobank in March 2018.	MGI	Michigan Genomics Initiative	Fixed threshold (5e-09)	UKB GWAS (ICD10)	UKB_GWAS	https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761	6	6.6e-31	0.0125318	0.0958		0.575	0.559-0.592	OR	2.26	1.49-3.43	2.26	1.49-3.43	2.27	1.68-3.06	2.27	1.68-3.06	1.96	1.59-2.42	1.96	1.59-2.42	1.85	1.58-2.17	1.85	1.58-2.17	1.85	1.64-2.09	1.85	1.64-2.09	1.12	0.93-1.35	0.23	1.51	1.27-1.8	4.61e-06	2.24	1.9-2.64	1.96e-21	True	False	False	False	Both	1325	10649	GRCh37/hg19	P<=5e-09					2020-06-08
prsweb-phecode172-1-gwas-catalog-r2019-05-03-x172-1-p-5e-09-mgi-20200608	prsweb-phecode172-1-gwas-catalog-r2019-05-03-x172-1-p-5e-09-mgi-20200608	PRSWEB_PHECODE172.1_GWAS-Catalog-r2019-05-03-X172.1_P_5e-09_MGI_20200608	P_5e-09	PRSWEB_PHECODE172.1_GWAS-Catalog-r2019-05-03-X172.1_P_5e-09_MGI_20200608	172.1	Melanoma;Cutaneous malignant melanoma	Binary	33 unique SNPs	MGI	Michigan Genomics Initiative	Fixed threshold (5e-09)	GWAS Catalog (2019-05-03)	18488026;19578364;21983785;21983787;23455637;26237428;28212542	https://www.ncbi.nlm.nih.gov/pubmed/?term=18488026+19578364+21983785+21983787+23455637+26237428+28212542	12	3.5e-36	0.0252311	0.0954		0.598	0.582-0.614	OR	2.92	2-4.26	2.92	2-4.26	2.98	2.28-3.91	2.98	2.28-3.91	2.35	1.93-2.85	2.35	1.93-2.85	1.96	1.68-2.29	1.96	1.68-2.29	1.83	1.62-2.06	1.83	1.62-2.06	1.33	1.1-1.61	0.00335	1.73	1.44-2.07	3.88e-09	2.5	2.1-2.97	4.26e-25	True	False	False	False	Both	1325	10649	GRCh37/hg19	P<=5e-09					2020-06-08
prsweb-phecode172-1-melanoma-ransohoff-p-5e-09-mgi-20200608	prsweb-phecode172-1-melanoma-ransohoff-p-5e-09-mgi-20200608	PRSWEB_PHECODE172.1_Melanoma-Ransohoff_P_5e-09_MGI_20200608	P_5e-09	PRSWEB_PHECODE172.1_Melanoma-Ransohoff_P_5e-09_MGI_20200608	172.1	Melanomas of skin, dx or hx	Binary	known and novel	MGI	Michigan Genomics Initiative	Fixed threshold (5e-09)	Ransohoff KJ et al. 2017	28212542	https://www.ncbi.nlm.nih.gov/pubmed/?term=28212542	15	1.2e-35	0.0269493	0.0954		0.603	0.587-0.619	OR	3.18	2.2-4.61	3.18	2.2-4.61	3.06	2.34-4.01	3.06	2.34-4.01	2.33	1.91-2.84	2.33	1.91-2.84	1.89	1.62-2.22	1.89	1.62-2.22	1.9	1.68-2.14	1.9	1.68-2.14	1.27	1.05-1.54	0.0123	1.63	1.36-1.95	1.72e-07	2.48	2.09-2.95	4.71e-25	True	False	False	False	Both	1325	10649	GRCh37/hg19	P<=5e-09					2020-06-08
prsweb-phecode172-1-ukbb-saige-hrc-x172-1-p-5e-09-mgi-20200608	prsweb-phecode172-1-ukbb-saige-hrc-x172-1-p-5e-09-mgi-20200608	PRSWEB_PHECODE172.1_UKBB-SAIGE-HRC-X172.1_P_5e-09_MGI_20200608	P_5e-09	PRSWEB_PHECODE172.1_UKBB-SAIGE-HRC-X172.1_P_5e-09_MGI_20200608	172.1	Melanomas of skin, dx or hx	Binary	ICD9 and ICD10 based PheWAS codes	MGI	Michigan Genomics Initiative	Fixed threshold (5e-09)	UKB GWAS (PheCode)	UKB_GWAS	https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761	9	3.3e-37	0.0146047	0.0955		0.588	0.573-0.605	OR	2.82	1.92-4.14	2.82	1.92-4.14	2.49	1.86-3.33	2.49	1.86-3.33	2.26	1.85-2.76	2.26	1.85-2.76	2.03	1.74-2.37	2.03	1.74-2.37	1.75	1.55-1.97	1.75	1.55-1.97	1.35	1.12-1.64	0.00191	1.89	1.58-2.26	4.94e-12	2.47	2.08-2.94	2.34e-24	True	False	False	False	Both	1325	10649	GRCh37/hg19	P<=5e-09					2020-06-08
prsweb-phecode172-1-20001-1059-p-5e-08-mgi-20200608	prsweb-phecode172-1-20001-1059-p-5e-08-mgi-20200608	PRSWEB_PHECODE172.1_20001-1059_P_5e-08_MGI_20200608	P_5e-08	PRSWEB_PHECODE172.1_20001-1059_P_5e-08_MGI_20200608	172.1	Cancer code, self-reported: malignant melanoma	Binary	GWAS round 2: Results shared 1st August 2018. Imputed genotypes from HRC plus UK10K & 1000 Genomes reference panels as released by UK Biobank in March 2018.	MGI	Michigan Genomics Initiative	GWAS Hits	UKB GWAS (PHESANT)	UKB_GWAS	https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761	10	5.4e-32	0.0132834	0.0957		0.576	0.561-0.593	OR	2.25	1.48-3.42	2.25	1.48-3.42	2.49	1.86-3.34	2.49	1.86-3.34	2.32	1.9-2.82	2.32	1.9-2.82	2.16	1.85-2.51	2.16	1.85-2.51	1.68	1.48-1.89	1.68	1.48-1.89	1.12	0.927-1.34	0.247	1.54	1.3-1.83	1.11e-06	2.05	1.74-2.42	3.04e-17	True	False	False	True	Both	1325	10649	GRCh37/hg19	P<=5e-08	https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000408/ScoringFiles/	https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000408/ScoringFiles/	/larsf/prsweb-data/cancerprsweb/releases/cancerprsweb_20200608/phewas/PRSWEB_PHECODE172.1_20001-1059_P_5e-08_MGI_20200608/all.tsv	/larsf/prsweb-data/cancerprsweb/releases/cancerprsweb_20200608/phewas/PRSWEB_PHECODE172.1_20001-1059_P_5e-08_MGI_20200608/exclusion.tsv	2020-06-08
prsweb-phecode172-1-c3-melanoma-skin-p-5e-08-mgi-20200608	prsweb-phecode172-1-c3-melanoma-skin-p-5e-08-mgi-20200608	PRSWEB_PHECODE172.1_C3-MELANOMA-SKIN_P_5e-08_MGI_20200608	P_5e-08	PRSWEB_PHECODE172.1_C3-MELANOMA-SKIN_P_5e-08_MGI_20200608	172.1	Malignant melanoma of skin	Binary	GWAS round 2: Results shared 1st August 2018. Imputed genotypes from HRC plus UK10K & 1000 Genomes reference panels as released by UK Biobank in March 2018.	MGI	Michigan Genomics Initiative	GWAS Hits	UKB GWAS (FINNGEN)	UKB_GWAS	https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761	16	9.4e-35	0.0135386	0.0955		0.585	0.569-0.6	OR	3.26	2.26-4.7	3.26	2.26-4.7	2.66	2-3.52	2.66	2-3.52	2.12	1.73-2.59	2.12	1.73-2.59	2.05	1.76-2.39	2.05	1.76-2.39	1.89	1.68-2.13	1.89	1.68-2.13	1.27	1.05-1.53	0.0125	1.52	1.27-1.81	6.26e-06	2.39	2.02-2.83	3.78e-24	True	False	False	True	Both	1325	10649	GRCh37/hg19	P<=5e-08	https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000412/ScoringFiles/	https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000412/ScoringFiles/	/larsf/prsweb-data/cancerprsweb/releases/cancerprsweb_20200608/phewas/PRSWEB_PHECODE172.1_C3-MELANOMA-SKIN_P_5e-08_MGI_20200608/all.tsv	/larsf/prsweb-data/cancerprsweb/releases/cancerprsweb_20200608/phewas/PRSWEB_PHECODE172.1_C3-MELANOMA-SKIN_P_5e-08_MGI_20200608/exclusion.tsv	2020-06-08
prsweb-phecode172-1-c43-p-5e-08-mgi-20200608	prsweb-phecode172-1-c43-p-5e-08-mgi-20200608	PRSWEB_PHECODE172.1_C43_P_5e-08_MGI_20200608	P_5e-08	PRSWEB_PHECODE172.1_C43_P_5e-08_MGI_20200608	172.1	Diagnoses - main ICD10: C43 Malignant melanoma of skin	Binary	GWAS round 2: Results shared 1st August 2018. Imputed genotypes from HRC plus UK10K & 1000 Genomes reference panels as released by UK Biobank in March 2018.	MGI	Michigan Genomics Initiative	GWAS Hits	UKB GWAS (ICD10)	UKB_GWAS	https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761	9	5.2e-43	0.0173798	0.0952		0.598	0.582-0.613	OR	2.88	1.96-4.21	2.88	1.96-4.21	2.6	1.95-3.46	2.6	1.95-3.46	2.4	1.98-2.92	2.4	1.98-2.92	2.16	1.86-2.51	2.16	1.86-2.51	1.93	1.71-2.18	1.93	1.71-2.18	1.25	1.03-1.51	0.0253	1.8	1.5-2.16	1.85e-10	2.62	2.21-3.11	5.81e-28	True	False	False	True	Both	1325	10649	GRCh37/hg19	P<=5e-08	https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000416/ScoringFiles/	https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000416/ScoringFiles/	/larsf/prsweb-data/cancerprsweb/releases/cancerprsweb_20200608/phewas/PRSWEB_PHECODE172.1_C43_P_5e-08_MGI_20200608/all.tsv	/larsf/prsweb-data/cancerprsweb/releases/cancerprsweb_20200608/phewas/PRSWEB_PHECODE172.1_C43_P_5e-08_MGI_20200608/exclusion.tsv	2020-06-08
prsweb-phecode172-1-gwas-catalog-r2019-05-03-x172-1-p-5e-08-mgi-20200608	prsweb-phecode172-1-gwas-catalog-r2019-05-03-x172-1-p-5e-08-mgi-20200608	PRSWEB_PHECODE172.1_GWAS-Catalog-r2019-05-03-X172.1_P_5e-08_MGI_20200608	P_5e-08	PRSWEB_PHECODE172.1_GWAS-Catalog-r2019-05-03-X172.1_P_5e-08_MGI_20200608	172.1	Melanoma;Cutaneous malignant melanoma	Binary	33 unique SNPs	MGI	Michigan Genomics Initiative	GWAS Hits	GWAS Catalog (2019-05-03)	18488026;19578364;21983785;21983787;23455637;26237428;28212542	https://www.ncbi.nlm.nih.gov/pubmed/?term=18488026+19578364+21983785+21983787+23455637+26237428+28212542	18	1.3e-35	0.0272086	0.0955		0.6	0.584-0.616	OR	2.39	1.58-3.61	2.39	1.58-3.61	2.53	1.9-3.38	2.53	1.9-3.38	2.21	1.81-2.7	2.21	1.81-2.7	2.08	1.78-2.43	2.08	1.78-2.43	1.84	1.63-2.08	1.84	1.63-2.08	1.3	1.07-1.57	0.00723	1.68	1.4-2.02	2.05e-08	2.49	2.1-2.96	4.28e-25	True	False	False	True	Both	1325	10649	GRCh37/hg19	P<=5e-08	https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000421/ScoringFiles/	https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000421/ScoringFiles/	/larsf/prsweb-data/cancerprsweb/releases/cancerprsweb_20200608/phewas/PRSWEB_PHECODE172.1_GWAS-Catalog-r2019-05-03-X172.1_P_5e-08_MGI_20200608/all.tsv	/larsf/prsweb-data/cancerprsweb/releases/cancerprsweb_20200608/phewas/PRSWEB_PHECODE172.1_GWAS-Catalog-r2019-05-03-X172.1_P_5e-08_MGI_20200608/exclusion.tsv	2020-06-08
prsweb-phecode172-1-melanoma-ransohoff-p-5e-08-mgi-20200608	prsweb-phecode172-1-melanoma-ransohoff-p-5e-08-mgi-20200608	PRSWEB_PHECODE172.1_Melanoma-Ransohoff_P_5e-08_MGI_20200608	P_5e-08	PRSWEB_PHECODE172.1_Melanoma-Ransohoff_P_5e-08_MGI_20200608	172.1	Melanomas of skin, dx or hx	Binary	known and novel	MGI	Michigan Genomics Initiative	GWAS Hits	Ransohoff KJ et al. 2017	28212542	https://www.ncbi.nlm.nih.gov/pubmed/?term=28212542	20	1.2e-34	0.0294901	0.0955		0.601	0.585-0.617	OR	2.54	1.7-3.8	2.54	1.7-3.8	2.78	2.1-3.69	2.78	2.1-3.69	2.16	1.77-2.64	2.16	1.77-2.64	1.88	1.6-2.2	1.88	1.6-2.2	1.61	1.43-1.82	1.61	1.43-1.82	1.24	1.02-1.51	0.0291	2.04	1.71-2.44	3.81e-15	2.34	1.97-2.8	2.66e-21	True	False	False	True	Both	1325	10649	GRCh37/hg19	P<=5e-08	https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000425/ScoringFiles/	https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000425/ScoringFiles/	/larsf/prsweb-data/cancerprsweb/releases/cancerprsweb_20200608/phewas/PRSWEB_PHECODE172.1_Melanoma-Ransohoff_P_5e-08_MGI_20200608/all.tsv	/larsf/prsweb-data/cancerprsweb/releases/cancerprsweb_20200608/phewas/PRSWEB_PHECODE172.1_Melanoma-Ransohoff_P_5e-08_MGI_20200608/exclusion.tsv	2020-06-08
prsweb-phecode172-1-ukbb-saige-hrc-x172-1-p-5e-08-mgi-20200608	prsweb-phecode172-1-ukbb-saige-hrc-x172-1-p-5e-08-mgi-20200608	PRSWEB_PHECODE172.1_UKBB-SAIGE-HRC-X172.1_P_5e-08_MGI_20200608	P_5e-08	PRSWEB_PHECODE172.1_UKBB-SAIGE-HRC-X172.1_P_5e-08_MGI_20200608	172.1	Melanomas of skin, dx or hx	Binary	ICD9 and ICD10 based PheWAS codes	MGI	Michigan Genomics Initiative	GWAS Hits	UKB GWAS (PheCode)	UKB_GWAS	https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761	12	8e-47	0.0206972	0.0951		0.606	0.591-0.622	OR	2.62	1.77-3.88	2.62	1.77-3.88	2.95	2.24-3.89	2.95	2.24-3.89	2.55	2.1-3.09	2.55	2.1-3.09	2.29	1.97-2.66	2.29	1.97-2.66	1.91	1.69-2.15	1.91	1.69-2.15	1.47	1.2-1.79	0.000155	2.18	1.81-2.63	3.85e-16	2.95	2.46-3.54	7.57e-32	True	False	False	True	Both	1325	10649	GRCh37/hg19	P<=5e-08	https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000429/ScoringFiles/	https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000429/ScoringFiles/	/larsf/prsweb-data/cancerprsweb/releases/cancerprsweb_20200608/phewas/PRSWEB_PHECODE172.1_UKBB-SAIGE-HRC-X172.1_P_5e-08_MGI_20200608/all.tsv	/larsf/prsweb-data/cancerprsweb/releases/cancerprsweb_20200608/phewas/PRSWEB_PHECODE172.1_UKBB-SAIGE-HRC-X172.1_P_5e-08_MGI_20200608/exclusion.tsv	2020-06-08
prsweb-phecode172-1-20001-1059-pt-mgi-20200608	prsweb-phecode172-1-20001-1059-pt-mgi-20200608	PRSWEB_PHECODE172.1_20001-1059_PT_MGI_20200608	P&T	PRSWEB_PHECODE172.1_20001-1059_PT_MGI_20200608	172.1	Cancer code, self-reported: malignant melanoma	Binary	GWAS round 2: Results shared 1st August 2018. Imputed genotypes from HRC plus UK10K & 1000 Genomes reference panels as released by UK Biobank in March 2018.	MGI	Michigan Genomics Initiative	P&T	UKB GWAS (PHESANT)	UKB_GWAS	https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761	7	4.2e-35	0.0147874	0.0956		0.578	0.562-0.594	OR	2.65	1.79-3.93	2.65	1.79-3.93	2.27	1.68-3.07	2.27	1.68-3.07	2.31	1.9-2.82	2.31	1.9-2.82	2.19	1.88-2.55	2.19	1.88-2.55	1.7	1.51-1.92	1.7	1.51-1.92	1.29	1.07-1.56	0.00911	1.88	1.57-2.24	5.9e-12	2.37	1.99-2.81	1.92e-22	True	False	False	True	Both	1325	10649	GRCh37/hg19	P<=2e-11	https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000410/ScoringFiles/	https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000410/ScoringFiles/	/larsf/prsweb-data/cancerprsweb/releases/cancerprsweb_20200608/phewas/PRSWEB_PHECODE172.1_20001-1059_PT_MGI_20200608/all.tsv	/larsf/prsweb-data/cancerprsweb/releases/cancerprsweb_20200608/phewas/PRSWEB_PHECODE172.1_20001-1059_PT_MGI_20200608/exclusion.tsv	2020-06-08
prsweb-phecode172-1-c3-melanoma-skin-pt-mgi-20200608	prsweb-phecode172-1-c3-melanoma-skin-pt-mgi-20200608	PRSWEB_PHECODE172.1_C3-MELANOMA-SKIN_PT_MGI_20200608	P&T	PRSWEB_PHECODE172.1_C3-MELANOMA-SKIN_PT_MGI_20200608	172.1	Malignant melanoma of skin	Binary	GWAS round 2: Results shared 1st August 2018. Imputed genotypes from HRC plus UK10K & 1000 Genomes reference panels as released by UK Biobank in March 2018.	MGI	Michigan Genomics Initiative	P&T	UKB GWAS (FINNGEN)	UKB_GWAS	https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761	21	4.9e-38	0.0166749	0.0954		0.593	0.576-0.609	OR	2.97	2.02-4.36	2.97	2.02-4.36	2.52	1.89-3.36	2.52	1.89-3.36	2.25	1.84-2.75	2.25	1.84-2.75	2.2	1.89-2.56	2.2	1.89-2.56	1.99	1.76-2.24	1.99	1.76-2.24	1.11	0.919-1.34	0.279	1.51	1.27-1.81	5.21e-06	2.41	2.04-2.85	4.43e-25	True	False	False	True	Both	1325	10649	GRCh37/hg19	P<=1.26e-07	https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000414/ScoringFiles/	https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000414/ScoringFiles/	/larsf/prsweb-data/cancerprsweb/releases/cancerprsweb_20200608/phewas/PRSWEB_PHECODE172.1_C3-MELANOMA-SKIN_PT_MGI_20200608/all.tsv	/larsf/prsweb-data/cancerprsweb/releases/cancerprsweb_20200608/phewas/PRSWEB_PHECODE172.1_C3-MELANOMA-SKIN_PT_MGI_20200608/exclusion.tsv	2020-06-08
prsweb-phecode172-1-c43-pt-mgi-20200608	prsweb-phecode172-1-c43-pt-mgi-20200608	PRSWEB_PHECODE172.1_C43_PT_MGI_20200608	P&T	PRSWEB_PHECODE172.1_C43_PT_MGI_20200608	172.1	Diagnoses - main ICD10: C43 Malignant melanoma of skin	Binary	GWAS round 2: Results shared 1st August 2018. Imputed genotypes from HRC plus UK10K & 1000 Genomes reference panels as released by UK Biobank in March 2018.	MGI	Michigan Genomics Initiative	P&T	UKB GWAS (ICD10)	UKB_GWAS	https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761	9	5.2e-43	0.0173798	0.0952		0.598	0.582-0.613	OR	2.88	1.96-4.21	2.88	1.96-4.21	2.6	1.95-3.46	2.6	1.95-3.46	2.4	1.98-2.92	2.4	1.98-2.92	2.16	1.86-2.51	2.16	1.86-2.51	1.93	1.71-2.18	1.93	1.71-2.18	1.25	1.03-1.51	0.0253	1.8	1.5-2.16	1.85e-10	2.62	2.21-3.11	5.81e-28	True	False	False	True	Both	1325	10649	GRCh37/hg19	P<=5e-08	https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000418/ScoringFiles/	https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000418/ScoringFiles/	/larsf/prsweb-data/cancerprsweb/releases/cancerprsweb_20200608/phewas/PRSWEB_PHECODE172.1_C43_PT_MGI_20200608/all.tsv	/larsf/prsweb-data/cancerprsweb/releases/cancerprsweb_20200608/phewas/PRSWEB_PHECODE172.1_C43_PT_MGI_20200608/exclusion.tsv	2020-06-08
prsweb-phecode172-1-d03-pt-mgi-20200608	prsweb-phecode172-1-d03-pt-mgi-20200608	PRSWEB_PHECODE172.1_D03_PT_MGI_20200608	P&T	PRSWEB_PHECODE172.1_D03_PT_MGI_20200608	172.1	Diagnoses - main ICD10: D03 Melanoma in situ	Binary	GWAS round 2: Results shared 1st August 2018. Imputed genotypes from HRC plus UK10K & 1000 Genomes reference panels as released by UK Biobank in March 2018.	MGI	Michigan Genomics Initiative	P&T	UKB GWAS (ICD10)	UKB_GWAS	https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761	147	0.027	0.000596512	0.0969		0.516	0.5-0.533	OR	1.07	0.603-1.9	1.07	0.603-1.9	1.17	0.788-1.73	1.17	0.788-1.73	1.14	0.887-1.47	1.14	0.887-1.47	1.13	0.939-1.36	1.13	0.939-1.36	1.14	1-1.3	1.14	1-1.3	1.06	0.897-1.25	0.499	1.07	0.903-1.26	0.452	1.18	1-1.39	0.0458	True	False	False	True	Both	1325	10649	GRCh37/hg19	P<=7.94e-05	https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000420/ScoringFiles/	https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000420/ScoringFiles/	/larsf/prsweb-data/cancerprsweb/releases/cancerprsweb_20200608/phewas/PRSWEB_PHECODE172.1_D03_PT_MGI_20200608/all.tsv	/larsf/prsweb-data/cancerprsweb/releases/cancerprsweb_20200608/phewas/PRSWEB_PHECODE172.1_D03_PT_MGI_20200608/exclusion.tsv	2020-06-08
prsweb-phecode172-1-gwas-catalog-r2019-05-03-x172-1-pt-mgi-20200608	prsweb-phecode172-1-gwas-catalog-r2019-05-03-x172-1-pt-mgi-20200608	PRSWEB_PHECODE172.1_GWAS-Catalog-r2019-05-03-X172.1_PT_MGI_20200608	P&T	PRSWEB_PHECODE172.1_GWAS-Catalog-r2019-05-03-X172.1_PT_MGI_20200608	172.1	Melanoma;Cutaneous malignant melanoma	Binary	33 unique SNPs	MGI	Michigan Genomics Initiative	P&T	GWAS Catalog (2019-05-03)	18488026;19578364;21983785;21983787;23455637;26237428;28212542	https://www.ncbi.nlm.nih.gov/pubmed/?term=18488026+19578364+21983785+21983787+23455637+26237428+28212542	29	2.4e-39	0.0286498	0.0954		0.608	0.592-0.623	OR	2.93	2-4.3	2.93	2-4.3	2.8	2.11-3.7	2.8	2.11-3.7	1.94	1.57-2.38	1.94	1.57-2.38	1.86	1.59-2.18	1.86	1.59-2.18	1.89	1.67-2.13	1.89	1.67-2.13	1.34	1.1-1.62	0.00342	1.85	1.54-2.22	4.13e-11	2.65	2.23-3.16	1.12e-27	True	False	False	True	Both	1325	10649	GRCh37/hg19	P<=1e-06	https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000423/ScoringFiles/	https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000423/ScoringFiles/	/larsf/prsweb-data/cancerprsweb/releases/cancerprsweb_20200608/phewas/PRSWEB_PHECODE172.1_GWAS-Catalog-r2019-05-03-X172.1_PT_MGI_20200608/all.tsv	/larsf/prsweb-data/cancerprsweb/releases/cancerprsweb_20200608/phewas/PRSWEB_PHECODE172.1_GWAS-Catalog-r2019-05-03-X172.1_PT_MGI_20200608/exclusion.tsv	2020-06-08
prsweb-phecode172-1-melanoma-ransohoff-pt-mgi-20200608	prsweb-phecode172-1-melanoma-ransohoff-pt-mgi-20200608	PRSWEB_PHECODE172.1_Melanoma-Ransohoff_PT_MGI_20200608	P&T	PRSWEB_PHECODE172.1_Melanoma-Ransohoff_PT_MGI_20200608	172.1	Melanomas of skin, dx or hx	Binary	known and novel	MGI	Michigan Genomics Initiative	P&T	Ransohoff KJ et al. 2017	28212542	https://www.ncbi.nlm.nih.gov/pubmed/?term=28212542	20	1.2e-34	0.0294901	0.0955		0.601	0.585-0.617	OR	2.54	1.7-3.8	2.54	1.7-3.8	2.78	2.1-3.69	2.78	2.1-3.69	2.16	1.77-2.64	2.16	1.77-2.64	1.88	1.6-2.2	1.88	1.6-2.2	1.61	1.43-1.82	1.61	1.43-1.82	1.24	1.02-1.51	0.0291	2.04	1.71-2.44	3.81e-15	2.34	1.97-2.8	2.66e-21	True	False	False	True	Both	1325	10649	GRCh37/hg19	P<=3.5e-08	https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000427/ScoringFiles/	https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000427/ScoringFiles/	/larsf/prsweb-data/cancerprsweb/releases/cancerprsweb_20200608/phewas/PRSWEB_PHECODE172.1_Melanoma-Ransohoff_PT_MGI_20200608/all.tsv	/larsf/prsweb-data/cancerprsweb/releases/cancerprsweb_20200608/phewas/PRSWEB_PHECODE172.1_Melanoma-Ransohoff_PT_MGI_20200608/exclusion.tsv	2020-06-08
prsweb-phecode172-1-ukbb-saige-hrc-x172-1-pt-mgi-20200608	prsweb-phecode172-1-ukbb-saige-hrc-x172-1-pt-mgi-20200608	PRSWEB_PHECODE172.1_UKBB-SAIGE-HRC-X172.1_PT_MGI_20200608	P&T	PRSWEB_PHECODE172.1_UKBB-SAIGE-HRC-X172.1_PT_MGI_20200608	172.1	Melanomas of skin, dx or hx	Binary	ICD9 and ICD10 based PheWAS codes	MGI	Michigan Genomics Initiative	P&T	UKB GWAS (PheCode)	UKB_GWAS	https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761	15	9.1e-44	0.0210935	0.0952		0.604	0.587-0.62	OR	2.97	2.04-4.34	2.97	2.04-4.34	2.95	2.24-3.88	2.95	2.24-3.88	2.32	1.9-2.82	2.32	1.9-2.82	2.28	1.96-2.64	2.28	1.96-2.64	1.92	1.71-2.17	1.92	1.71-2.17	1.33	1.09-1.62	0.00443	1.92	1.6-2.31	2.92e-12	2.72	2.29-3.25	4.95e-29	True	False	False	True	Both	1325	10649	GRCh37/hg19	P<=2e-07	https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000431/ScoringFiles/	https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000431/ScoringFiles/	/larsf/prsweb-data/cancerprsweb/releases/cancerprsweb_20200608/phewas/PRSWEB_PHECODE172.1_UKBB-SAIGE-HRC-X172.1_PT_MGI_20200608/all.tsv	/larsf/prsweb-data/cancerprsweb/releases/cancerprsweb_20200608/phewas/PRSWEB_PHECODE172.1_UKBB-SAIGE-HRC-X172.1_PT_MGI_20200608/exclusion.tsv	2020-06-08
prsweb-phecode172-1-20001-1059-prs-cs-mgi-20200608	prsweb-phecode172-1-20001-1059-prs-cs-mgi-20200608	PRSWEB_PHECODE172.1_20001-1059_PRS-CS_MGI_20200608	PRS-CS	PRSWEB_PHECODE172.1_20001-1059_PRS-CS_MGI_20200608	172.1	Cancer code, self-reported: malignant melanoma	Binary	GWAS round 2: Results shared 1st August 2018. Imputed genotypes from HRC plus UK10K & 1000 Genomes reference panels as released by UK Biobank in March 2018.	MGI	Michigan Genomics Initiative	PRS-CS	UKB GWAS (PHESANT)	UKB_GWAS	https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761	1111490	1.8e-09	0.00512413	0.0966		0.547	0.531-0.563	OR	1.94	1.25-3.02	1.94	1.25-3.02	1.6	1.14-2.24	1.6	1.14-2.24	1.7	1.37-2.1	1.7	1.37-2.1	1.53	1.29-1.81	1.53	1.29-1.81	1.37	1.21-1.55	1.37	1.21-1.55	1.32	1.11-1.56	0.00147	1.16	0.975-1.38	0.0931	1.58	1.34-1.86	6.41e-08	True	False	False	True	Both	1325	10649	GRCh37/hg19	auto	https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000409/ScoringFiles/	https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000409/ScoringFiles/	/larsf/prsweb-data/cancerprsweb/releases/cancerprsweb_20200608/phewas/PRSWEB_PHECODE172.1_20001-1059_PRS-CS_MGI_20200608/all.tsv	/larsf/prsweb-data/cancerprsweb/releases/cancerprsweb_20200608/phewas/PRSWEB_PHECODE172.1_20001-1059_PRS-CS_MGI_20200608/exclusion.tsv	2020-06-08
prsweb-phecode172-1-c3-melanoma-skin-prs-cs-mgi-20200608	prsweb-phecode172-1-c3-melanoma-skin-prs-cs-mgi-20200608	PRSWEB_PHECODE172.1_C3-MELANOMA-SKIN_PRS-CS_MGI_20200608	PRS-CS	PRSWEB_PHECODE172.1_C3-MELANOMA-SKIN_PRS-CS_MGI_20200608	172.1	Malignant melanoma of skin	Binary	GWAS round 2: Results shared 1st August 2018. Imputed genotypes from HRC plus UK10K & 1000 Genomes reference panels as released by UK Biobank in March 2018.	MGI	Michigan Genomics Initiative	PRS-CS	UKB GWAS (FINNGEN)	UKB_GWAS	https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761	1111490	4.6e-16	0.00825925	0.0964		0.568	0.552-0.584	OR	2.09	1.35-3.22	2.09	1.35-3.22	2.02	1.48-2.77	2.02	1.48-2.77	1.54	1.23-1.93	1.54	1.23-1.93	1.44	1.22-1.71	1.44	1.22-1.71	1.55	1.38-1.76	1.55	1.38-1.76	1.12	0.933-1.34	0.225	1.43	1.21-1.7	4.33e-05	1.84	1.56-2.17	5.7e-13	True	False	False	True	Both	1325	10649	GRCh37/hg19	auto	https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000413/ScoringFiles/	https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000413/ScoringFiles/	/larsf/prsweb-data/cancerprsweb/releases/cancerprsweb_20200608/phewas/PRSWEB_PHECODE172.1_C3-MELANOMA-SKIN_PRS-CS_MGI_20200608/all.tsv	/larsf/prsweb-data/cancerprsweb/releases/cancerprsweb_20200608/phewas/PRSWEB_PHECODE172.1_C3-MELANOMA-SKIN_PRS-CS_MGI_20200608/exclusion.tsv	2020-06-08
prsweb-phecode172-1-c43-prs-cs-mgi-20200608	prsweb-phecode172-1-c43-prs-cs-mgi-20200608	PRSWEB_PHECODE172.1_C43_PRS-CS_MGI_20200608	PRS-CS	PRSWEB_PHECODE172.1_C43_PRS-CS_MGI_20200608	172.1	Diagnoses - main ICD10: C43 Malignant melanoma of skin	Binary	GWAS round 2: Results shared 1st August 2018. Imputed genotypes from HRC plus UK10K & 1000 Genomes reference panels as released by UK Biobank in March 2018.	MGI	Michigan Genomics Initiative	PRS-CS	UKB GWAS (ICD10)	UKB_GWAS	https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761	1109519	3e-12	0.00370256	0.0965		0.556	0.541-0.571	OR	1.88	1.2-2.95	1.88	1.2-2.95	1.56	1.11-2.19	1.56	1.11-2.19	1.51	1.21-1.9	1.51	1.21-1.9	1.55	1.31-1.83	1.55	1.31-1.83	1.43	1.26-1.62	1.43	1.26-1.62	1.21	1.02-1.44	0.0316	1.24	1.04-1.48	0.0142	1.63	1.38-1.92	5.38e-09	True	False	False	True	Both	1325	10649	GRCh37/hg19	auto	https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000417/ScoringFiles/	https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000417/ScoringFiles/	/larsf/prsweb-data/cancerprsweb/releases/cancerprsweb_20200608/phewas/PRSWEB_PHECODE172.1_C43_PRS-CS_MGI_20200608/all.tsv	/larsf/prsweb-data/cancerprsweb/releases/cancerprsweb_20200608/phewas/PRSWEB_PHECODE172.1_C43_PRS-CS_MGI_20200608/exclusion.tsv	2020-06-08
prsweb-phecode172-1-d03-prs-cs-mgi-20200608	prsweb-phecode172-1-d03-prs-cs-mgi-20200608	PRSWEB_PHECODE172.1_D03_PRS-CS_MGI_20200608	PRS-CS	PRSWEB_PHECODE172.1_D03_PRS-CS_MGI_20200608	172.1	Diagnoses - main ICD10: D03 Melanoma in situ	Binary	GWAS round 2: Results shared 1st August 2018. Imputed genotypes from HRC plus UK10K & 1000 Genomes reference panels as released by UK Biobank in March 2018.	MGI	Michigan Genomics Initiative	PRS-CS	UKB GWAS (ICD10)	UKB_GWAS	https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761	1080882	0.16	0.00165781	0.0969		0.513	0.496-0.529	OR	1.18	0.697-2	1.18	0.697-2	1.15	0.785-1.68	1.15	0.785-1.68	0.981	0.753-1.28	0.981	0.753-1.28	1.04	0.865-1.26	1.04	0.865-1.26	1.01	0.884-1.15	1.01	0.884-1.15	1.07	0.907-1.26	0.422	1.16	0.988-1.37	0.0687	1.09	0.925-1.29	0.299	False	False	False	False	Both	1325	10649	GRCh37/hg19	auto					2020-06-08
prsweb-phecode172-1-ukbb-saige-hrc-x172-1-prs-cs-mgi-20200608	prsweb-phecode172-1-ukbb-saige-hrc-x172-1-prs-cs-mgi-20200608	PRSWEB_PHECODE172.1_UKBB-SAIGE-HRC-X172.1_PRS-CS_MGI_20200608	PRS-CS	PRSWEB_PHECODE172.1_UKBB-SAIGE-HRC-X172.1_PRS-CS_MGI_20200608	172.1	Melanomas of skin, dx or hx	Binary	ICD9 and ICD10 based PheWAS codes	MGI	Michigan Genomics Initiative	PRS-CS	UKB GWAS (PheCode)	UKB_GWAS	https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761	1119238	2e-11	0.00690566	0.0965		0.555	0.54-0.573	OR	1.64	1.01-2.66	1.64	1.01-2.66	1.53	1.08-2.16	1.53	1.08-2.16	1.41	1.12-1.78	1.41	1.12-1.78	1.41	1.19-1.68	1.41	1.19-1.68	1.52	1.34-1.72	1.52	1.34-1.72	1.08	0.908-1.29	0.38	1.2	1.01-1.42	0.04	1.65	1.41-1.94	1.04e-09	True	False	False	True	Both	1325	10649	GRCh37/hg19	auto	https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000430/ScoringFiles/	https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000430/ScoringFiles/	/larsf/prsweb-data/cancerprsweb/releases/cancerprsweb_20200608/phewas/PRSWEB_PHECODE172.1_UKBB-SAIGE-HRC-X172.1_PRS-CS_MGI_20200608/all.tsv	/larsf/prsweb-data/cancerprsweb/releases/cancerprsweb_20200608/phewas/PRSWEB_PHECODE172.1_UKBB-SAIGE-HRC-X172.1_PRS-CS_MGI_20200608/exclusion.tsv	2020-06-08
prsweb-phecode172-1-20001-1059-lassosum-mgi-20200608	prsweb-phecode172-1-20001-1059-lassosum-mgi-20200608	PRSWEB_PHECODE172.1_20001-1059_LASSOSUM_MGI_20200608	Lassosum	PRSWEB_PHECODE172.1_20001-1059_LASSOSUM_MGI_20200608	172.1	Cancer code, self-reported: malignant melanoma	Binary	GWAS round 2: Results shared 1st August 2018. Imputed genotypes from HRC plus UK10K & 1000 Genomes reference panels as released by UK Biobank in March 2018.	MGI	Michigan Genomics Initiative	lassosum	UKB GWAS (PHESANT)	UKB_GWAS	https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761	185	9.8e-34	0.0175399	0.0957		0.571	0.555-0.587	OR	2	1.29-3.09	2	1.29-3.09	2.34	1.74-3.14	2.34	1.74-3.14	2.23	1.83-2.73	2.23	1.83-2.73	2.07	1.77-2.42	2.07	1.77-2.42	1.86	1.65-2.1	1.86	1.65-2.1	1.29	1.07-1.56	0.00798	1.64	1.37-1.97	6.52e-08	2.43	2.05-2.88	1.83e-24	True	False	False	True	Both	1325	10649	GRCh37/hg19	s=0.2;Lambda=0.03793	https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000411/ScoringFiles/	https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000411/ScoringFiles/	/larsf/prsweb-data/cancerprsweb/releases/cancerprsweb_20200608/phewas/PRSWEB_PHECODE172.1_20001-1059_LASSOSUM_MGI_20200608/all.tsv	/larsf/prsweb-data/cancerprsweb/releases/cancerprsweb_20200608/phewas/PRSWEB_PHECODE172.1_20001-1059_LASSOSUM_MGI_20200608/exclusion.tsv	2020-06-08
prsweb-phecode172-1-c3-melanoma-skin-lassosum-mgi-20200608	prsweb-phecode172-1-c3-melanoma-skin-lassosum-mgi-20200608	PRSWEB_PHECODE172.1_C3-MELANOMA-SKIN_LASSOSUM_MGI_20200608	Lassosum	PRSWEB_PHECODE172.1_C3-MELANOMA-SKIN_LASSOSUM_MGI_20200608	172.1	Malignant melanoma of skin	Binary	GWAS round 2: Results shared 1st August 2018. Imputed genotypes from HRC plus UK10K & 1000 Genomes reference panels as released by UK Biobank in March 2018.	MGI	Michigan Genomics Initiative	lassosum	UKB GWAS (FINNGEN)	UKB_GWAS	https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761	505	6.5e-34	0.0175778	0.0957		0.578	0.562-0.595	OR	2.34	1.55-3.53	2.34	1.55-3.53	2.25	1.67-3.03	2.25	1.67-3.03	2.13	1.74-2.61	2.13	1.74-2.61	1.82	1.55-2.14	1.82	1.55-2.14	1.88	1.67-2.12	1.88	1.67-2.12	1.27	1.05-1.53	0.0146	1.64	1.37-1.96	8.49e-08	2.45	2.06-2.9	1.04e-24	True	False	False	True	Both	1325	10649	GRCh37/hg19	s=0.2;Lambda=0.03793	https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000415/ScoringFiles/	https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000415/ScoringFiles/	/larsf/prsweb-data/cancerprsweb/releases/cancerprsweb_20200608/phewas/PRSWEB_PHECODE172.1_C3-MELANOMA-SKIN_LASSOSUM_MGI_20200608/all.tsv	/larsf/prsweb-data/cancerprsweb/releases/cancerprsweb_20200608/phewas/PRSWEB_PHECODE172.1_C3-MELANOMA-SKIN_LASSOSUM_MGI_20200608/exclusion.tsv	2020-06-08
prsweb-phecode172-1-c43-lassosum-mgi-20200608	prsweb-phecode172-1-c43-lassosum-mgi-20200608	PRSWEB_PHECODE172.1_C43_LASSOSUM_MGI_20200608	Lassosum	PRSWEB_PHECODE172.1_C43_LASSOSUM_MGI_20200608	172.1	Diagnoses - main ICD10: C43 Malignant melanoma of skin	Binary	GWAS round 2: Results shared 1st August 2018. Imputed genotypes from HRC plus UK10K & 1000 Genomes reference panels as released by UK Biobank in March 2018.	MGI	Michigan Genomics Initiative	lassosum	UKB GWAS (ICD10)	UKB_GWAS	https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761	436	5.6e-29	0.0133171	0.0959		0.565	0.549-0.583	OR	1.93	1.24-3	1.93	1.24-3	2.16	1.59-2.93	2.16	1.59-2.93	2	1.63-2.46	2	1.63-2.46	1.79	1.53-2.1	1.79	1.53-2.1	1.73	1.53-1.95	1.73	1.53-1.95	1.18	0.973-1.42	0.0926	1.79	1.5-2.14	1.07e-10	2.28	1.92-2.7	3.47e-21	True	False	False	True	Both	1325	10649	GRCh37/hg19	s=0.5;Lambda=0.04833	https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000419/ScoringFiles/	https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000419/ScoringFiles/	/larsf/prsweb-data/cancerprsweb/releases/cancerprsweb_20200608/phewas/PRSWEB_PHECODE172.1_C43_LASSOSUM_MGI_20200608/all.tsv	/larsf/prsweb-data/cancerprsweb/releases/cancerprsweb_20200608/phewas/PRSWEB_PHECODE172.1_C43_LASSOSUM_MGI_20200608/exclusion.tsv	2020-06-08
prsweb-phecode172-1-d03-lassosum-mgi-20200608	prsweb-phecode172-1-d03-lassosum-mgi-20200608	PRSWEB_PHECODE172.1_D03_LASSOSUM_MGI_20200608	Lassosum	PRSWEB_PHECODE172.1_D03_LASSOSUM_MGI_20200608	172.1	Diagnoses - main ICD10: D03 Melanoma in situ	Binary	GWAS round 2: Results shared 1st August 2018. Imputed genotypes from HRC plus UK10K & 1000 Genomes reference panels as released by UK Biobank in March 2018.	MGI	Michigan Genomics Initiative	lassosum	UKB GWAS (ICD10)	UKB_GWAS	https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761	3838429	0.18	0.00201622	0.0969		0.512	0.496-0.528	OR	1.54	0.96-2.46	1.54	0.96-2.46	1.08	0.73-1.6	1.08	0.73-1.6	0.936	0.716-1.22	0.936	0.716-1.22	1.08	0.894-1.29	1.08	0.894-1.29	1.06	0.93-1.21	1.06	0.93-1.21	1.13	0.955-1.33	0.158	1.12	0.946-1.32	0.191	1.16	0.981-1.36	0.0827	False	False	False	False	Both	1325	10649	GRCh37/hg19	s=1;Lambda=0.006952					2020-06-08
prsweb-phecode172-1-ukbb-saige-hrc-x172-1-lassosum-mgi-20200608	prsweb-phecode172-1-ukbb-saige-hrc-x172-1-lassosum-mgi-20200608	PRSWEB_PHECODE172.1_UKBB-SAIGE-HRC-X172.1_LASSOSUM_MGI_20200608	Lassosum	PRSWEB_PHECODE172.1_UKBB-SAIGE-HRC-X172.1_LASSOSUM_MGI_20200608	172.1	Melanomas of skin, dx or hx	Binary	ICD9 and ICD10 based PheWAS codes	MGI	Michigan Genomics Initiative	lassosum	UKB GWAS (PheCode)	UKB_GWAS	https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761	296	1.1e-33	0.0185378	0.0957		0.582	0.566-0.599	OR	1.99	1.29-3.07	1.99	1.29-3.07	1.85	1.34-2.55	1.85	1.34-2.55	2.17	1.77-2.65	2.17	1.77-2.65	1.97	1.68-2.3	1.97	1.68-2.3	1.85	1.64-2.09	1.85	1.64-2.09	1.38	1.14-1.67	0.000856	1.79	1.49-2.15	4.19e-10	2.55	2.15-3.04	3.72e-26	True	False	False	True	Both	1325	10649	GRCh37/hg19	s=0.2;Lambda=0.03793	https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000432/ScoringFiles/	https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000432/ScoringFiles/	/larsf/prsweb-data/cancerprsweb/releases/cancerprsweb_20200608/phewas/PRSWEB_PHECODE172.1_UKBB-SAIGE-HRC-X172.1_LASSOSUM_MGI_20200608/all.tsv	/larsf/prsweb-data/cancerprsweb/releases/cancerprsweb_20200608/phewas/PRSWEB_PHECODE172.1_UKBB-SAIGE-HRC-X172.1_LASSOSUM_MGI_20200608/exclusion.tsv	2020-06-08