prs_id slug legacy_id legacy_model prswebprefix trait_code trait_name trait_type description cohort cohort_label method gwas_source reference_label reference_url snp_count p_value pseudo_r2 brier_score mse aauc aauc_ci effect_metric top_effect_1 top_effect_1_ci top_or_1 top_or_1_ci top_effect_2 top_effect_2_ci top_or_2 top_or_2_ci top_effect_5 top_effect_5_ci top_or_5 top_or_5_ci top_effect_10 top_effect_10_ci top_or_10 top_or_10_ci top_effect_25 top_effect_25_ci top_or_25 top_or_25_ci q1_vs_q2_effect q1_vs_q2_effect_ci q1_vs_q2_p_value q1_vs_q3_effect q1_vs_q3_effect_ci q1_vs_q3_p_value q1_vs_q4_effect q1_vs_q4_effect_ci q1_vs_q4_p_value nominally_significant reversed_effect_warning underpowered_warning upload_to_portal sex cases controls genome_build tuning_parameter weights_external_url weights_url phewas_download_url exclusion_download_url last_updated prsweb-phecode172-22-gwas-catalog-r2019-05-03-x172-22-p-5e-05-mgi-20200608 prsweb-phecode172-22-gwas-catalog-r2019-05-03-x172-22-p-5e-05-mgi-20200608 PRSWEB_PHECODE172.22_GWAS-Catalog-r2019-05-03-X172.22_P_5e-05_MGI_20200608 P_5e-05 PRSWEB_PHECODE172.22_GWAS-Catalog-r2019-05-03-X172.22_P_5e-05_MGI_20200608 172.22 Squamous cell carcinoma;Cutaneous squamous cell carcinoma Binary 19 unique SNPs MGI Michigan Genomics Initiative Fixed threshold (5e-05) GWAS Catalog (2019-05-03) 26829030;26908436;27424798 https://www.ncbi.nlm.nih.gov/pubmed/?term=26829030+26908436+27424798 18 8.6e-21 0.0178049 0.0983 0.581 0.56-0.599 OR 2.33 1.44-3.77 2.33 1.44-3.77 2.88 2.08-4 2.88 2.08-4 2.21 1.74-2.81 2.21 1.74-2.81 2 1.66-2.4 2 1.66-2.4 1.68 1.46-1.94 1.68 1.46-1.94 1.61 1.3-1.99 1.12e-05 1.59 1.28-1.96 2.41e-05 2.36 1.93-2.89 8.58e-17 True False False False Both 982 7491 GRCh37/hg19 P<=5e-05 2020-06-08 prsweb-phecode172-22-cscc-chahal-p-5e-05-mgi-20200608 prsweb-phecode172-22-cscc-chahal-p-5e-05-mgi-20200608 PRSWEB_PHECODE172.22_cSCC-Chahal_P_5e-05_MGI_20200608 P_5e-05 PRSWEB_PHECODE172.22_cSCC-Chahal_P_5e-05_MGI_20200608 172.22 Squamous cell carcinoma Binary known and novel MGI Michigan Genomics Initiative Fixed threshold (5e-05) Chahal HS et al. 2018 27424798 https://www.ncbi.nlm.nih.gov/pubmed/?term=27424798 10 4e-30 0.0295004 0.0976 0.589 0.57-0.61 OR 4.54 3.07-6.71 4.54 3.07-6.71 3 2.17-4.14 3 2.17-4.14 2.48 1.98-3.12 2.48 1.98-3.12 2.13 1.78-2.55 2.13 1.78-2.55 1.87 1.62-2.15 1.87 1.62-2.15 1.26 1.01-1.57 0.0386 1.58 1.28-1.94 2.12e-05 2.42 1.98-2.95 4.09e-18 True False False False Both 982 7491 GRCh37/hg19 P<=5e-05 2020-06-08 prsweb-phecode172-22-20001-1062-p-5e-06-mgi-20200608 prsweb-phecode172-22-20001-1062-p-5e-06-mgi-20200608 PRSWEB_PHECODE172.22_20001-1062_P_5e-06_MGI_20200608 P_5e-06 PRSWEB_PHECODE172.22_20001-1062_P_5e-06_MGI_20200608 172.22 Cancer code, self-reported: squamous cell carcinoma Binary GWAS round 2: Results shared 1st August 2018. Imputed genotypes from HRC plus UK10K & 1000 Genomes reference panels as released by UK Biobank in March 2018. MGI Michigan Genomics Initiative Fixed threshold (5e-06) UKB GWAS (PHESANT) UKB_GWAS https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761 19 0.9 0.000135558 0.0998 0.49 0.471-0.508 OR 1.22 0.66-2.25 1.22 0.66-2.25 1.08 0.681-1.72 1.08 0.681-1.72 1.17 0.877-1.56 1.17 0.877-1.56 1.08 0.866-1.34 1.08 0.866-1.34 0.989 0.847-1.16 0.989 0.847-1.16 0.897 0.743-1.08 0.261 0.936 0.775-1.13 0.491 0.929 0.77-1.12 0.439 False False False False Both 982 7491 GRCh37/hg19 P<=5e-06 2020-06-08 prsweb-phecode172-22-gwas-catalog-r2019-05-03-x172-22-p-5e-06-mgi-20200608 prsweb-phecode172-22-gwas-catalog-r2019-05-03-x172-22-p-5e-06-mgi-20200608 PRSWEB_PHECODE172.22_GWAS-Catalog-r2019-05-03-X172.22_P_5e-06_MGI_20200608 P_5e-06 PRSWEB_PHECODE172.22_GWAS-Catalog-r2019-05-03-X172.22_P_5e-06_MGI_20200608 172.22 Squamous cell carcinoma;Cutaneous squamous cell carcinoma Binary 19 unique SNPs MGI Michigan Genomics Initiative Fixed threshold (5e-06) GWAS Catalog (2019-05-03) 26829030;26908436;27424798 https://www.ncbi.nlm.nih.gov/pubmed/?term=26829030+26908436+27424798 17 4.7e-22 0.02034 0.0982 0.584 0.565-0.601 OR 2.24 1.35-3.71 2.24 1.35-3.71 2.48 1.76-3.5 2.48 1.76-3.5 2.23 1.76-2.83 2.23 1.76-2.83 2.03 1.7-2.44 2.03 1.7-2.44 1.65 1.43-1.91 1.65 1.43-1.91 1.23 0.994-1.53 0.0569 1.64 1.34-2.02 1.96e-06 2.13 1.75-2.59 6.33e-14 True False False False Both 982 7491 GRCh37/hg19 P<=5e-06 2020-06-08 prsweb-phecode172-22-cscc-chahal-p-5e-06-mgi-20200608 prsweb-phecode172-22-cscc-chahal-p-5e-06-mgi-20200608 PRSWEB_PHECODE172.22_cSCC-Chahal_P_5e-06_MGI_20200608 P_5e-06 PRSWEB_PHECODE172.22_cSCC-Chahal_P_5e-06_MGI_20200608 172.22 Squamous cell carcinoma Binary known and novel MGI Michigan Genomics Initiative Fixed threshold (5e-06) Chahal HS et al. 2018 27424798 https://www.ncbi.nlm.nih.gov/pubmed/?term=27424798 10 4e-30 0.0295004 0.0976 0.589 0.57-0.61 OR 4.54 3.07-6.71 4.54 3.07-6.71 3 2.17-4.14 3 2.17-4.14 2.48 1.98-3.12 2.48 1.98-3.12 2.13 1.78-2.55 2.13 1.78-2.55 1.87 1.62-2.15 1.87 1.62-2.15 1.26 1.01-1.57 0.0386 1.58 1.28-1.94 2.12e-05 2.42 1.98-2.95 4.09e-18 True False False False Both 982 7491 GRCh37/hg19 P<=5e-06 2020-06-08 prsweb-phecode172-22-gwas-catalog-r2019-05-03-x172-22-p-5e-07-mgi-20200608 prsweb-phecode172-22-gwas-catalog-r2019-05-03-x172-22-p-5e-07-mgi-20200608 PRSWEB_PHECODE172.22_GWAS-Catalog-r2019-05-03-X172.22_P_5e-07_MGI_20200608 P_5e-07 PRSWEB_PHECODE172.22_GWAS-Catalog-r2019-05-03-X172.22_P_5e-07_MGI_20200608 172.22 Squamous cell carcinoma;Cutaneous squamous cell carcinoma Binary 19 unique SNPs MGI Michigan Genomics Initiative Fixed threshold (5e-07) GWAS Catalog (2019-05-03) 26829030;26908436;27424798 https://www.ncbi.nlm.nih.gov/pubmed/?term=26829030+26908436+27424798 14 6.4e-31 0.0290945 0.0975 0.597 0.578-0.616 OR 3.57 2.33-5.47 3.57 2.33-5.47 3.31 2.42-4.52 3.31 2.42-4.52 2.7 2.16-3.37 2.7 2.16-3.37 2.23 1.86-2.66 2.23 1.86-2.66 1.93 1.68-2.23 1.93 1.68-2.23 1.43 1.15-1.78 0.00128 1.62 1.31-2.01 9.72e-06 2.63 2.15-3.22 5.29e-21 True False False False Both 982 7491 GRCh37/hg19 P<=5e-07 2020-06-08 prsweb-phecode172-22-cscc-chahal-p-5e-07-mgi-20200608 prsweb-phecode172-22-cscc-chahal-p-5e-07-mgi-20200608 PRSWEB_PHECODE172.22_cSCC-Chahal_P_5e-07_MGI_20200608 P_5e-07 PRSWEB_PHECODE172.22_cSCC-Chahal_P_5e-07_MGI_20200608 172.22 Squamous cell carcinoma Binary known and novel MGI Michigan Genomics Initiative Fixed threshold (5e-07) Chahal HS et al. 2018 27424798 https://www.ncbi.nlm.nih.gov/pubmed/?term=27424798 10 4e-30 0.0295004 0.0976 0.589 0.57-0.61 OR 4.54 3.07-6.71 4.54 3.07-6.71 3 2.17-4.14 3 2.17-4.14 2.48 1.98-3.12 2.48 1.98-3.12 2.13 1.78-2.55 2.13 1.78-2.55 1.87 1.62-2.15 1.87 1.62-2.15 1.26 1.01-1.57 0.0386 1.58 1.28-1.94 2.12e-05 2.42 1.98-2.95 4.09e-18 True False False False Both 982 7491 GRCh37/hg19 P<=5e-07 2020-06-08 prsweb-phecode172-22-gwas-catalog-r2019-05-03-x172-22-p-5e-09-mgi-20200608 prsweb-phecode172-22-gwas-catalog-r2019-05-03-x172-22-p-5e-09-mgi-20200608 PRSWEB_PHECODE172.22_GWAS-Catalog-r2019-05-03-X172.22_P_5e-09_MGI_20200608 P_5e-09 PRSWEB_PHECODE172.22_GWAS-Catalog-r2019-05-03-X172.22_P_5e-09_MGI_20200608 172.22 Squamous cell carcinoma;Cutaneous squamous cell carcinoma Binary 19 unique SNPs MGI Michigan Genomics Initiative Fixed threshold (5e-09) GWAS Catalog (2019-05-03) 26829030;26908436;27424798 https://www.ncbi.nlm.nih.gov/pubmed/?term=26829030+26908436+27424798 7 2.3e-28 0.0297042 0.0977 0.593 0.573-0.613 OR 3.74 2.46-5.68 3.74 2.46-5.68 2.87 2.07-3.97 2.87 2.07-3.97 2.45 1.95-3.08 2.45 1.95-3.08 2.28 1.91-2.72 2.28 1.91-2.72 1.95 1.69-2.24 1.95 1.69-2.24 1.45 1.17-1.8 0.000805 1.52 1.23-1.88 0.000138 2.57 2.11-3.14 2.31e-20 True False False False Both 982 7491 GRCh37/hg19 P<=5e-09 2020-06-08 prsweb-phecode172-22-cscc-chahal-p-5e-09-mgi-20200608 prsweb-phecode172-22-cscc-chahal-p-5e-09-mgi-20200608 PRSWEB_PHECODE172.22_cSCC-Chahal_P_5e-09_MGI_20200608 P_5e-09 PRSWEB_PHECODE172.22_cSCC-Chahal_P_5e-09_MGI_20200608 172.22 Squamous cell carcinoma Binary known and novel MGI Michigan Genomics Initiative Fixed threshold (5e-09) Chahal HS et al. 2018 27424798 https://www.ncbi.nlm.nih.gov/pubmed/?term=27424798 5 2.4e-27 0.031315 0.0979 0.583 0.563-0.603 OR 3.65 2.41-5.53 3.65 2.41-5.53 3.11 2.26-4.28 3.11 2.26-4.28 2.35 1.86-2.96 2.35 1.86-2.96 2.11 1.76-2.53 2.11 1.76-2.53 1.9 1.65-2.19 1.9 1.65-2.19 1.05 0.843-1.31 0.655 1.55 1.26-1.9 3.36e-05 2.29 1.88-2.78 1.29e-16 True False False False Both 982 7491 GRCh37/hg19 P<=5e-09 2020-06-08 prsweb-phecode172-22-gwas-catalog-r2019-05-03-x172-22-p-5e-08-mgi-20200608 prsweb-phecode172-22-gwas-catalog-r2019-05-03-x172-22-p-5e-08-mgi-20200608 PRSWEB_PHECODE172.22_GWAS-Catalog-r2019-05-03-X172.22_P_5e-08_MGI_20200608 P_5e-08 PRSWEB_PHECODE172.22_GWAS-Catalog-r2019-05-03-X172.22_P_5e-08_MGI_20200608 172.22 Squamous cell carcinoma;Cutaneous squamous cell carcinoma Binary 19 unique SNPs MGI Michigan Genomics Initiative GWAS Hits GWAS Catalog (2019-05-03) 26829030;26908436;27424798 https://www.ncbi.nlm.nih.gov/pubmed/?term=26829030+26908436+27424798 13 3.7e-32 0.0285817 0.0974 0.599 0.579-0.618 OR 3.51 2.29-5.39 3.51 2.29-5.39 3.41 2.5-4.64 3.41 2.5-4.64 2.61 2.08-3.26 2.61 2.08-3.26 2.26 1.89-2.7 2.26 1.89-2.7 1.87 1.63-2.16 1.87 1.63-2.16 1.45 1.17-1.81 0.000892 1.74 1.41-2.16 3.67e-07 2.66 2.17-3.26 6.19e-21 True False False True Both 982 7491 GRCh37/hg19 P<=5e-08 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000461/ScoringFiles/ https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000461/ScoringFiles/ /larsf/prsweb-data/cancerprsweb/releases/cancerprsweb_20200608/phewas/PRSWEB_PHECODE172.22_GWAS-Catalog-r2019-05-03-X172.22_P_5e-08_MGI_20200608/all.tsv /larsf/prsweb-data/cancerprsweb/releases/cancerprsweb_20200608/phewas/PRSWEB_PHECODE172.22_GWAS-Catalog-r2019-05-03-X172.22_P_5e-08_MGI_20200608/exclusion.tsv 2020-06-08 prsweb-phecode172-22-cscc-chahal-p-5e-08-mgi-20200608 prsweb-phecode172-22-cscc-chahal-p-5e-08-mgi-20200608 PRSWEB_PHECODE172.22_cSCC-Chahal_P_5e-08_MGI_20200608 P_5e-08 PRSWEB_PHECODE172.22_cSCC-Chahal_P_5e-08_MGI_20200608 172.22 Squamous cell carcinoma Binary known and novel MGI Michigan Genomics Initiative GWAS Hits Chahal HS et al. 2018 27424798 https://www.ncbi.nlm.nih.gov/pubmed/?term=27424798 10 4e-30 0.0295004 0.0976 0.589 0.57-0.61 OR 4.54 3.07-6.71 4.54 3.07-6.71 3 2.17-4.14 3 2.17-4.14 2.48 1.98-3.12 2.48 1.98-3.12 2.13 1.78-2.55 2.13 1.78-2.55 1.87 1.62-2.15 1.87 1.62-2.15 1.26 1.01-1.57 0.0386 1.58 1.28-1.94 2.12e-05 2.42 1.98-2.95 4.09e-18 True False False True Both 982 7491 GRCh37/hg19 P<=5e-08 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000465/ScoringFiles/ https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000465/ScoringFiles/ /larsf/prsweb-data/cancerprsweb/releases/cancerprsweb_20200608/phewas/PRSWEB_PHECODE172.22_cSCC-Chahal_P_5e-08_MGI_20200608/all.tsv /larsf/prsweb-data/cancerprsweb/releases/cancerprsweb_20200608/phewas/PRSWEB_PHECODE172.22_cSCC-Chahal_P_5e-08_MGI_20200608/exclusion.tsv 2020-06-08 prsweb-phecode172-22-gwas-catalog-r2019-05-03-x172-22-pt-mgi-20200608 prsweb-phecode172-22-gwas-catalog-r2019-05-03-x172-22-pt-mgi-20200608 PRSWEB_PHECODE172.22_GWAS-Catalog-r2019-05-03-X172.22_PT_MGI_20200608 P&T PRSWEB_PHECODE172.22_GWAS-Catalog-r2019-05-03-X172.22_PT_MGI_20200608 172.22 Squamous cell carcinoma;Cutaneous squamous cell carcinoma Binary 19 unique SNPs MGI Michigan Genomics Initiative P&T GWAS Catalog (2019-05-03) 26829030;26908436;27424798 https://www.ncbi.nlm.nih.gov/pubmed/?term=26829030+26908436+27424798 7 2.3e-28 0.0297042 0.0977 0.593 0.573-0.613 OR 3.74 2.46-5.68 3.74 2.46-5.68 2.87 2.07-3.97 2.87 2.07-3.97 2.45 1.95-3.08 2.45 1.95-3.08 2.28 1.91-2.72 2.28 1.91-2.72 1.95 1.69-2.24 1.95 1.69-2.24 1.45 1.17-1.8 0.000805 1.52 1.23-1.88 0.000138 2.57 2.11-3.14 2.31e-20 True False False True Both 982 7491 GRCh37/hg19 P<=1e-11 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000463/ScoringFiles/ https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000463/ScoringFiles/ /larsf/prsweb-data/cancerprsweb/releases/cancerprsweb_20200608/phewas/PRSWEB_PHECODE172.22_GWAS-Catalog-r2019-05-03-X172.22_PT_MGI_20200608/all.tsv /larsf/prsweb-data/cancerprsweb/releases/cancerprsweb_20200608/phewas/PRSWEB_PHECODE172.22_GWAS-Catalog-r2019-05-03-X172.22_PT_MGI_20200608/exclusion.tsv 2020-06-08 prsweb-phecode172-22-cscc-chahal-pt-mgi-20200608 prsweb-phecode172-22-cscc-chahal-pt-mgi-20200608 PRSWEB_PHECODE172.22_cSCC-Chahal_PT_MGI_20200608 P&T PRSWEB_PHECODE172.22_cSCC-Chahal_PT_MGI_20200608 172.22 Squamous cell carcinoma Binary known and novel MGI Michigan Genomics Initiative P&T Chahal HS et al. 2018 27424798 https://www.ncbi.nlm.nih.gov/pubmed/?term=27424798 6 1.2e-27 0.0314978 0.0978 0.583 0.564-0.603 OR 3.75 2.49-5.64 3.75 2.49-5.64 3.3 2.41-4.5 3.3 2.41-4.5 2.36 1.87-2.97 2.36 1.87-2.97 2.07 1.73-2.49 2.07 1.73-2.49 1.87 1.63-2.16 1.87 1.63-2.16 1.08 0.868-1.34 0.498 1.45 1.18-1.78 0.000428 2.19 1.8-2.66 2.4e-15 True False False True Both 982 7491 GRCh37/hg19 P<=7.94e-09 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000467/ScoringFiles/ https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000467/ScoringFiles/ /larsf/prsweb-data/cancerprsweb/releases/cancerprsweb_20200608/phewas/PRSWEB_PHECODE172.22_cSCC-Chahal_PT_MGI_20200608/all.tsv /larsf/prsweb-data/cancerprsweb/releases/cancerprsweb_20200608/phewas/PRSWEB_PHECODE172.22_cSCC-Chahal_PT_MGI_20200608/exclusion.tsv 2020-06-08 prsweb-phecode172-22-20001-1062-prs-cs-mgi-20200608 prsweb-phecode172-22-20001-1062-prs-cs-mgi-20200608 PRSWEB_PHECODE172.22_20001-1062_PRS-CS_MGI_20200608 PRS-CS PRSWEB_PHECODE172.22_20001-1062_PRS-CS_MGI_20200608 172.22 Cancer code, self-reported: squamous cell carcinoma Binary GWAS round 2: Results shared 1st August 2018. Imputed genotypes from HRC plus UK10K & 1000 Genomes reference panels as released by UK Biobank in March 2018. MGI Michigan Genomics Initiative PRS-CS UKB GWAS (PHESANT) UKB_GWAS https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761 1064109 0.15 0.000162382 0.0997 0.512 0.493-0.532 OR 1.67 0.961-2.89 1.67 0.961-2.89 1.14 0.721-1.79 1.14 0.721-1.79 1.15 0.86-1.54 1.15 0.86-1.54 1.23 0.997-1.52 1.23 0.997-1.52 1.12 0.966-1.31 1.12 0.966-1.31 0.815 0.67-0.99 0.0395 0.989 0.82-1.19 0.909 1.04 0.862-1.25 0.706 False False False False Both 982 7491 GRCh37/hg19 auto 2020-06-08 prsweb-phecode172-22-20001-1062-lassosum-mgi-20200608 prsweb-phecode172-22-20001-1062-lassosum-mgi-20200608 PRSWEB_PHECODE172.22_20001-1062_LASSOSUM_MGI_20200608 Lassosum PRSWEB_PHECODE172.22_20001-1062_LASSOSUM_MGI_20200608 172.22 Cancer code, self-reported: squamous cell carcinoma Binary GWAS round 2: Results shared 1st August 2018. Imputed genotypes from HRC plus UK10K & 1000 Genomes reference panels as released by UK Biobank in March 2018. MGI Michigan Genomics Initiative lassosum UKB GWAS (PHESANT) UKB_GWAS https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761 4279140 0.0076 0.00050461 0.0996 0.523 0.503-0.543 OR 1.56 0.892-2.74 1.56 0.892-2.74 1.47 0.971-2.22 1.47 0.971-2.22 1.5 1.15-1.95 1.5 1.15-1.95 1.23 0.994-1.51 1.23 0.994-1.51 1.18 1.02-1.37 1.18 1.02-1.37 0.945 0.778-1.15 0.572 1.05 0.87-1.28 0.594 1.18 0.98-1.42 0.0802 True False False True Both 982 7491 GRCh37/hg19 s=1;Lambda=0.00336 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000460/ScoringFiles/ https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000460/ScoringFiles/ /larsf/prsweb-data/cancerprsweb/releases/cancerprsweb_20200608/phewas/PRSWEB_PHECODE172.22_20001-1062_LASSOSUM_MGI_20200608/all.tsv /larsf/prsweb-data/cancerprsweb/releases/cancerprsweb_20200608/phewas/PRSWEB_PHECODE172.22_20001-1062_LASSOSUM_MGI_20200608/exclusion.tsv 2020-06-08