prs_id slug legacy_id legacy_model prswebprefix trait_code trait_name trait_type description cohort cohort_label method gwas_source reference_label reference_url snp_count p_value pseudo_r2 brier_score mse aauc aauc_ci effect_metric top_effect_1 top_effect_1_ci top_or_1 top_or_1_ci top_effect_2 top_effect_2_ci top_or_2 top_or_2_ci top_effect_5 top_effect_5_ci top_or_5 top_or_5_ci top_effect_10 top_effect_10_ci top_or_10 top_or_10_ci top_effect_25 top_effect_25_ci top_or_25 top_or_25_ci q1_vs_q2_effect q1_vs_q2_effect_ci q1_vs_q2_p_value q1_vs_q3_effect q1_vs_q3_effect_ci q1_vs_q3_p_value q1_vs_q4_effect q1_vs_q4_effect_ci q1_vs_q4_p_value nominally_significant reversed_effect_warning underpowered_warning upload_to_portal sex cases controls genome_build tuning_parameter weights_external_url weights_url phewas_download_url exclusion_download_url last_updated prsweb-phecode184-11-20001-1039-p-5e-05-mgi-20200608 prsweb-phecode184-11-20001-1039-p-5e-05-mgi-20200608 PRSWEB_PHECODE184.11_20001-1039_P_5e-05_MGI_20200608 P_5e-05 PRSWEB_PHECODE184.11_20001-1039_P_5e-05_MGI_20200608 184.11 Cancer code, self-reported: ovarian cancer Binary GWAS round 2: Results shared 1st August 2018. Imputed genotypes from HRC plus UK10K & 1000 Genomes reference panels as released by UK Biobank in March 2018. MGI Michigan Genomics Initiative Fixed threshold (5e-05) UKB GWAS (PHESANT) UKB_GWAS https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761 100 0.36 0.00192304 0.0829 0.514 0.466-0.558 OR 2.36 0.813-6.87 2.36 0.813-6.87 2.11 0.936-4.75 2.11 0.936-4.75 1.54 0.847-2.79 1.54 0.847-2.79 1.26 0.779-2.02 1.26 0.779-2.02 1.12 0.787-1.58 1.12 0.787-1.58 0.907 0.576-1.43 0.675 1.08 0.703-1.67 0.714 1.11 0.719-1.7 0.647 False False False False Female 174 1730 GRCh37/hg19 P<=5e-05 2020-06-08 prsweb-phecode184-11-c56-p-5e-05-mgi-20200608 prsweb-phecode184-11-c56-p-5e-05-mgi-20200608 PRSWEB_PHECODE184.11_C56_P_5e-05_MGI_20200608 P_5e-05 PRSWEB_PHECODE184.11_C56_P_5e-05_MGI_20200608 184.11 Diagnoses - main ICD10: C56 Malignant neoplasm of ovary Binary GWAS round 2: Results shared 1st August 2018. Imputed genotypes from HRC plus UK10K & 1000 Genomes reference panels as released by UK Biobank in March 2018. MGI Michigan Genomics Initiative Fixed threshold (5e-05) UKB GWAS (ICD10) UKB_GWAS https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761 101 0.49 4.73552e-05 0.0829 0.505 0.459-0.551 OR 1.35 0.347-5.26 1.35 0.347-5.26 1.28 0.47-3.5 1.28 0.47-3.5 1.71 0.959-3.06 1.71 0.959-3.06 1.2 0.741-1.96 1.2 0.741-1.96 1.02 0.716-1.46 1.02 0.716-1.46 0.987 0.636-1.53 0.953 1.02 0.66-1.58 0.928 1 0.649-1.55 0.984 False False False False Female 174 1730 GRCh37/hg19 P<=5e-05 2020-06-08 prsweb-phecode184-11-gwas-catalog-r2019-05-03-x184-11-p-5e-05-mgi-20200608 prsweb-phecode184-11-gwas-catalog-r2019-05-03-x184-11-p-5e-05-mgi-20200608 PRSWEB_PHECODE184.11_GWAS-Catalog-r2019-05-03-X184.11_P_5e-05_MGI_20200608 P_5e-05 PRSWEB_PHECODE184.11_GWAS-Catalog-r2019-05-03-X184.11_P_5e-05_MGI_20200608 184.11 Epithelial ovarian cancer;High-grade serous ovarian cancer;Serous invasive ovarian cancer;Invasive epithelial ovarian cancer;Mucinous ovarian carcinoma;Low-grade serous and serous borderline ovarian cancer;Serous borderline ovarian cancer;Ovarian cancer in BRCA1 mutation carriers;Ovarian cancer;Ovarian clear cell cancer Binary 32 unique SNPs MGI Michigan Genomics Initiative Fixed threshold (5e-05) GWAS Catalog (2019-05-03) 19648919;21964575;23544013;25581431;28346442 https://www.ncbi.nlm.nih.gov/pubmed/?term=19648919+21964575+23544013+25581431+28346442 25 0.15 0.00181869 0.0828 0.532 0.484-0.58 OR 1.37 0.351-5.35 1.37 0.351-5.35 1.29 0.473-3.52 1.29 0.473-3.52 1.2 0.619-2.33 1.2 0.619-2.33 0.879 0.51-1.51 0.879 0.51-1.51 1.19 0.843-1.68 1.19 0.843-1.68 1.16 0.727-1.85 0.535 1.36 0.864-2.13 0.185 1.4 0.898-2.19 0.137 False False False False Female 174 1730 GRCh37/hg19 P<=5e-05 2020-06-08 prsweb-phecode184-11-phelan-hsoc-p-5e-05-mgi-20200608 prsweb-phecode184-11-phelan-hsoc-p-5e-05-mgi-20200608 PRSWEB_PHECODE184.11_Phelan-HSOC_P_5e-05_MGI_20200608 P_5e-05 PRSWEB_PHECODE184.11_Phelan-HSOC_P_5e-05_MGI_20200608 184.11 High-grade serous ovarian cancer Binary High-grade serous ovarian cancer MGI Michigan Genomics Initiative Fixed threshold (5e-05) Phelan CM et al. 2017 28346442 https://www.ncbi.nlm.nih.gov/pubmed/?term=28346442 116 0.31 0.000774043 0.0829 0.513 0.473-0.557 OR 1.86 0.571-6.04 1.86 0.571-6.04 1.55 0.616-3.89 1.55 0.616-3.89 1.2 0.621-2.33 1.2 0.621-2.33 1.12 0.683-1.84 1.12 0.683-1.84 0.958 0.668-1.37 0.958 0.668-1.37 1.04 0.671-1.62 0.858 1.11 0.718-1.71 0.642 1.01 0.648-1.57 0.969 False False False False Female 174 1730 GRCh37/hg19 P<=5e-05 2020-06-08 prsweb-phecode184-11-phelan-ieoc-p-5e-05-mgi-20200608 prsweb-phecode184-11-phelan-ieoc-p-5e-05-mgi-20200608 PRSWEB_PHECODE184.11_Phelan-IEOC_P_5e-05_MGI_20200608 P_5e-05 PRSWEB_PHECODE184.11_Phelan-IEOC_P_5e-05_MGI_20200608 184.11 Invasive epithelial ovarian cancer Binary Invasive epithelial ovarian cancer MGI Michigan Genomics Initiative Fixed threshold (5e-05) Phelan CM et al. 2017 28346442 https://www.ncbi.nlm.nih.gov/pubmed/?term=28346442 219 0.4 1.94556e-05 0.0829 0.527 0.488-0.57 OR 0.814 0.148-4.49 0.814 0.148-4.49 0.71 0.193-2.61 0.71 0.193-2.61 0.844 0.393-1.81 0.844 0.393-1.81 0.945 0.556-1.61 0.945 0.556-1.61 0.991 0.693-1.42 0.991 0.693-1.42 1.2 0.754-1.9 0.447 1.52 0.979-2.37 0.0623 1.22 0.771-1.94 0.392 False False False False Female 174 1730 GRCh37/hg19 P<=5e-05 2020-06-08 prsweb-phecode184-11-phelan-mcoc-p-5e-05-mgi-20200608 prsweb-phecode184-11-phelan-mcoc-p-5e-05-mgi-20200608 PRSWEB_PHECODE184.11_Phelan-MCOC_P_5e-05_MGI_20200608 P_5e-05 PRSWEB_PHECODE184.11_Phelan-MCOC_P_5e-05_MGI_20200608 184.11 Mucinous ovarian carcinoma Binary Mucinous ovarian carcinoma MGI Michigan Genomics Initiative Fixed threshold (5e-05) Phelan CM et al. 2017 28346442 https://www.ncbi.nlm.nih.gov/pubmed/?term=28346442 131 0.13 0.000695458 0.0828 0.529 0.487-0.571 OR 1.81 0.556-5.91 1.81 0.556-5.91 1.25 0.458-3.42 1.25 0.458-3.42 1.3 0.686-2.46 1.3 0.686-2.46 1.37 0.864-2.18 1.37 0.864-2.18 1.2 0.852-1.7 1.2 0.852-1.7 1.57 1-2.46 0.0497 1.16 0.722-1.87 0.534 1.49 0.947-2.34 0.0848 False False False False Female 174 1730 GRCh37/hg19 P<=5e-05 2020-06-08 prsweb-phecode184-11-phelan-sioc-p-5e-05-mgi-20200608 prsweb-phecode184-11-phelan-sioc-p-5e-05-mgi-20200608 PRSWEB_PHECODE184.11_Phelan-SIOC_P_5e-05_MGI_20200608 P_5e-05 PRSWEB_PHECODE184.11_Phelan-SIOC_P_5e-05_MGI_20200608 184.11 Serous invasive ovarian cancer Binary Serous invasive ovarian cancer MGI Michigan Genomics Initiative Fixed threshold (5e-05) Phelan CM et al. 2017 28346442 https://www.ncbi.nlm.nih.gov/pubmed/?term=28346442 207 0.095 0.00273239 0.0828 0.552 0.506-0.59 OR 0.797 0.145-4.4 0.797 0.145-4.4 0.699 0.19-2.57 0.699 0.19-2.57 0.853 0.398-1.83 0.853 0.398-1.83 0.755 0.425-1.34 0.755 0.425-1.34 1.39 0.994-1.94 1.39 0.994-1.94 0.989 0.605-1.62 0.966 1.62 1.03-2.54 0.0358 1.66 1.07-2.6 0.025 False False False False Female 174 1730 GRCh37/hg19 P<=5e-05 2020-06-08 prsweb-phecode184-11-20001-1039-p-5e-06-mgi-20200608 prsweb-phecode184-11-20001-1039-p-5e-06-mgi-20200608 PRSWEB_PHECODE184.11_20001-1039_P_5e-06_MGI_20200608 P_5e-06 PRSWEB_PHECODE184.11_20001-1039_P_5e-06_MGI_20200608 184.11 Cancer code, self-reported: ovarian cancer Binary GWAS round 2: Results shared 1st August 2018. Imputed genotypes from HRC plus UK10K & 1000 Genomes reference panels as released by UK Biobank in March 2018. MGI Michigan Genomics Initiative Fixed threshold (5e-06) UKB GWAS (PHESANT) UKB_GWAS https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761 18 0.28 0.00168378 0.0829 0.503 0.46-0.549 OR 2.36 0.812-6.85 2.36 0.812-6.85 2.09 0.927-4.7 2.09 0.927-4.7 1.54 0.848-2.8 1.54 0.848-2.8 1.17 0.722-1.91 1.17 0.722-1.91 0.953 0.664-1.37 0.953 0.664-1.37 1.38 0.873-2.18 0.168 1.41 0.904-2.21 0.129 1.17 0.735-1.87 0.504 False False False False Female 174 1730 GRCh37/hg19 P<=5e-06 2020-06-08 prsweb-phecode184-11-c56-p-5e-06-mgi-20200608 prsweb-phecode184-11-c56-p-5e-06-mgi-20200608 PRSWEB_PHECODE184.11_C56_P_5e-06_MGI_20200608 P_5e-06 PRSWEB_PHECODE184.11_C56_P_5e-06_MGI_20200608 184.11 Diagnoses - main ICD10: C56 Malignant neoplasm of ovary Binary GWAS round 2: Results shared 1st August 2018. Imputed genotypes from HRC plus UK10K & 1000 Genomes reference panels as released by UK Biobank in March 2018. MGI Michigan Genomics Initiative Fixed threshold (5e-06) UKB GWAS (ICD10) UKB_GWAS https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761 10 0.52 0.0007011 0.0829 0.496 0.449-0.541 OR 1.41 0.36-5.49 1.41 0.36-5.49 0.714 0.194-2.63 0.714 0.194-2.63 1.59 0.872-2.88 1.59 0.872-2.88 1.53 0.975-2.39 1.53 0.975-2.39 1.11 0.782-1.57 1.11 0.782-1.57 0.512 0.316-0.829 0.00643 0.945 0.629-1.42 0.787 0.896 0.593-1.35 0.603 False False False False Female 174 1730 GRCh37/hg19 P<=5e-06 2020-06-08 prsweb-phecode184-11-gwas-catalog-r2019-05-03-x184-11-p-5e-06-mgi-20200608 prsweb-phecode184-11-gwas-catalog-r2019-05-03-x184-11-p-5e-06-mgi-20200608 PRSWEB_PHECODE184.11_GWAS-Catalog-r2019-05-03-X184.11_P_5e-06_MGI_20200608 P_5e-06 PRSWEB_PHECODE184.11_GWAS-Catalog-r2019-05-03-X184.11_P_5e-06_MGI_20200608 184.11 Epithelial ovarian cancer;High-grade serous ovarian cancer;Serous invasive ovarian cancer;Invasive epithelial ovarian cancer;Mucinous ovarian carcinoma;Low-grade serous and serous borderline ovarian cancer;Serous borderline ovarian cancer;Ovarian cancer in BRCA1 mutation carriers;Ovarian cancer;Ovarian clear cell cancer Binary 32 unique SNPs MGI Michigan Genomics Initiative Fixed threshold (5e-06) GWAS Catalog (2019-05-03) 19648919;21964575;23544013;25581431;28346442 https://www.ncbi.nlm.nih.gov/pubmed/?term=19648919+21964575+23544013+25581431+28346442 25 0.15 0.00181869 0.0828 0.532 0.484-0.58 OR 1.37 0.351-5.35 1.37 0.351-5.35 1.29 0.473-3.52 1.29 0.473-3.52 1.2 0.619-2.33 1.2 0.619-2.33 0.879 0.51-1.51 0.879 0.51-1.51 1.19 0.843-1.68 1.19 0.843-1.68 1.16 0.727-1.85 0.535 1.36 0.864-2.13 0.185 1.4 0.898-2.19 0.137 False False False False Female 174 1730 GRCh37/hg19 P<=5e-06 2020-06-08 prsweb-phecode184-11-phelan-epoc-p-5e-06-mgi-20200608 prsweb-phecode184-11-phelan-epoc-p-5e-06-mgi-20200608 PRSWEB_PHECODE184.11_Phelan-EPOC_P_5e-06_MGI_20200608 P_5e-06 PRSWEB_PHECODE184.11_Phelan-EPOC_P_5e-06_MGI_20200608 184.11 Epithelial ovarian cancer Binary Epithelial ovarian cancer MGI Michigan Genomics Initiative Fixed threshold (5e-06) Phelan CM et al. 2017 28346442 https://www.ncbi.nlm.nih.gov/pubmed/?term=28346442 26 0.44 0.000436443 0.0829 0.525 0.481-0.57 OR 1.34 0.343-5.22 1.34 0.343-5.22 0.967 0.316-2.96 0.967 0.316-2.96 0.831 0.388-1.78 0.831 0.388-1.78 1.18 0.726-1.92 1.18 0.726-1.92 1.24 0.882-1.75 1.24 0.882-1.75 0.879 0.555-1.39 0.584 1.1 0.712-1.71 0.662 1.26 0.819-1.93 0.295 False False False False Female 174 1730 GRCh37/hg19 P<=5e-06 2020-06-08 prsweb-phecode184-11-phelan-hsoc-p-5e-06-mgi-20200608 prsweb-phecode184-11-phelan-hsoc-p-5e-06-mgi-20200608 PRSWEB_PHECODE184.11_Phelan-HSOC_P_5e-06_MGI_20200608 P_5e-06 PRSWEB_PHECODE184.11_Phelan-HSOC_P_5e-06_MGI_20200608 184.11 High-grade serous ovarian cancer Binary High-grade serous ovarian cancer MGI Michigan Genomics Initiative Fixed threshold (5e-06) Phelan CM et al. 2017 28346442 https://www.ncbi.nlm.nih.gov/pubmed/?term=28346442 14 0.36 0.000809453 0.0829 0.514 0.472-0.558 OR 0 0-0 0 0-0 0.688 0.187-2.53 0.688 0.187-2.53 1.2 0.621-2.33 1.2 0.621-2.33 1.26 0.781-2.03 1.26 0.781-2.03 1.18 0.835-1.67 1.18 0.835-1.67 1.1 0.71-1.71 0.663 0.938 0.597-1.47 0.781 1.19 0.771-1.83 0.436 False False False False Female 174 1730 GRCh37/hg19 P<=5e-06 2020-06-08 prsweb-phecode184-11-phelan-ieoc-p-5e-06-mgi-20200608 prsweb-phecode184-11-phelan-ieoc-p-5e-06-mgi-20200608 PRSWEB_PHECODE184.11_Phelan-IEOC_P_5e-06_MGI_20200608 P_5e-06 PRSWEB_PHECODE184.11_Phelan-IEOC_P_5e-06_MGI_20200608 184.11 Invasive epithelial ovarian cancer Binary Invasive epithelial ovarian cancer MGI Michigan Genomics Initiative Fixed threshold (5e-06) Phelan CM et al. 2017 28346442 https://www.ncbi.nlm.nih.gov/pubmed/?term=28346442 54 0.03 0.000383676 0.0827 0.554 0.509-0.595 OR 0.806 0.146-4.44 0.806 0.146-4.44 0.99 0.323-3.03 0.99 0.323-3.03 0.847 0.395-1.82 0.847 0.395-1.82 1.24 0.772-2 1.24 0.772-2 1.11 0.782-1.57 1.11 0.782-1.57 2.17 1.34-3.52 0.00172 1.9 1.16-3.11 0.0107 1.81 1.11-2.97 0.0183 True False False False Female 174 1730 GRCh37/hg19 P<=5e-06 2020-06-08 prsweb-phecode184-11-phelan-lsasboc-p-5e-06-mgi-20200608 prsweb-phecode184-11-phelan-lsasboc-p-5e-06-mgi-20200608 PRSWEB_PHECODE184.11_Phelan-LSASBOC_P_5e-06_MGI_20200608 P_5e-06 PRSWEB_PHECODE184.11_Phelan-LSASBOC_P_5e-06_MGI_20200608 184.11 Low-grade serous and serous borderline ovarian cancer Binary Low-grade serous and serous borderline ovarian cancer MGI Michigan Genomics Initiative Fixed threshold (5e-06) Phelan CM et al. 2017 28346442 https://www.ncbi.nlm.nih.gov/pubmed/?term=28346442 28 0.84 0.00757031 0.0829 0.51 0.466-0.555 OR 0 0-0 0 0-0 0.135 0.00815-2.25 0.135 0.00815-2.25 0.486 0.186-1.27 0.486 0.186-1.27 0.926 0.546-1.57 0.926 0.546-1.57 1.15 0.813-1.63 1.15 0.813-1.63 0.788 0.503-1.24 0.299 0.953 0.62-1.46 0.827 1.03 0.679-1.58 0.874 False False False False Female 174 1730 GRCh37/hg19 P<=5e-06 2020-06-08 prsweb-phecode184-11-phelan-mcoc-p-5e-06-mgi-20200608 prsweb-phecode184-11-phelan-mcoc-p-5e-06-mgi-20200608 PRSWEB_PHECODE184.11_Phelan-MCOC_P_5e-06_MGI_20200608 P_5e-06 PRSWEB_PHECODE184.11_Phelan-MCOC_P_5e-06_MGI_20200608 184.11 Mucinous ovarian carcinoma Binary Mucinous ovarian carcinoma MGI Michigan Genomics Initiative Fixed threshold (5e-06) Phelan CM et al. 2017 28346442 https://www.ncbi.nlm.nih.gov/pubmed/?term=28346442 27 0.23 0.00203756 0.0829 0.525 0.484-0.57 OR 1.36 0.349-5.28 1.36 0.349-5.28 1.83 0.775-4.33 1.83 0.775-4.33 1.08 0.544-2.16 1.08 0.544-2.16 1.2 0.734-1.95 1.2 0.734-1.95 1.18 0.835-1.67 1.18 0.835-1.67 1.21 0.771-1.91 0.402 1.23 0.783-1.94 0.369 1.37 0.877-2.14 0.166 False False False False Female 174 1730 GRCh37/hg19 P<=5e-06 2020-06-08 prsweb-phecode184-11-phelan-occc-p-5e-06-mgi-20200608 prsweb-phecode184-11-phelan-occc-p-5e-06-mgi-20200608 PRSWEB_PHECODE184.11_Phelan-OCCC_P_5e-06_MGI_20200608 P_5e-06 PRSWEB_PHECODE184.11_Phelan-OCCC_P_5e-06_MGI_20200608 184.11 Ovarian clear cell cancer Binary Ovarian clear cell cancer MGI Michigan Genomics Initiative Fixed threshold (5e-06) Phelan CM et al. 2017 28346442 https://www.ncbi.nlm.nih.gov/pubmed/?term=28346442 12 0.31 0.000512137 0.0829 0.528 0.482-0.573 OR 3.59 1.42-9.08 3.59 1.42-9.08 3.36 1.68-6.69 3.36 1.68-6.69 1.73 0.968-3.09 1.73 0.968-3.09 1.21 0.743-1.97 1.21 0.743-1.97 1.07 0.748-1.52 1.07 0.748-1.52 1.02 0.657-1.6 0.916 1.13 0.728-1.74 0.592 1.13 0.73-1.76 0.575 False False False False Female 174 1730 GRCh37/hg19 P<=5e-06 2020-06-08 prsweb-phecode184-11-phelan-sioc-p-5e-06-mgi-20200608 prsweb-phecode184-11-phelan-sioc-p-5e-06-mgi-20200608 PRSWEB_PHECODE184.11_Phelan-SIOC_P_5e-06_MGI_20200608 P_5e-06 PRSWEB_PHECODE184.11_Phelan-SIOC_P_5e-06_MGI_20200608 184.11 Serous invasive ovarian cancer Binary Serous invasive ovarian cancer MGI Michigan Genomics Initiative Fixed threshold (5e-06) Phelan CM et al. 2017 28346442 https://www.ncbi.nlm.nih.gov/pubmed/?term=28346442 58 0.17 0.00147602 0.0829 0.535 0.491-0.577 OR 0 0-0 0 0-0 1.26 0.461-3.42 1.26 0.461-3.42 0.956 0.464-1.97 0.956 0.464-1.97 0.987 0.588-1.66 0.987 0.588-1.66 1.15 0.81-1.62 1.15 0.81-1.62 1.35 0.841-2.17 0.213 1.59 1.01-2.52 0.0457 1.5 0.947-2.38 0.0843 False False False False Female 174 1730 GRCh37/hg19 P<=5e-06 2020-06-08 prsweb-phecode184-11-gwas-catalog-r2019-05-03-x184-11-p-5e-07-mgi-20200608 prsweb-phecode184-11-gwas-catalog-r2019-05-03-x184-11-p-5e-07-mgi-20200608 PRSWEB_PHECODE184.11_GWAS-Catalog-r2019-05-03-X184.11_P_5e-07_MGI_20200608 P_5e-07 PRSWEB_PHECODE184.11_GWAS-Catalog-r2019-05-03-X184.11_P_5e-07_MGI_20200608 184.11 Epithelial ovarian cancer;High-grade serous ovarian cancer;Serous invasive ovarian cancer;Invasive epithelial ovarian cancer;Mucinous ovarian carcinoma;Low-grade serous and serous borderline ovarian cancer;Serous borderline ovarian cancer;Ovarian cancer in BRCA1 mutation carriers;Ovarian cancer;Ovarian clear cell cancer Binary 32 unique SNPs MGI Michigan Genomics Initiative Fixed threshold (5e-07) GWAS Catalog (2019-05-03) 19648919;21964575;23544013;25581431;28346442 https://www.ncbi.nlm.nih.gov/pubmed/?term=19648919+21964575+23544013+25581431+28346442 23 0.16 0.00155655 0.0828 0.531 0.481-0.578 OR 1.36 0.35-5.32 1.36 0.35-5.32 1.28 0.471-3.5 1.28 0.471-3.5 1.2 0.62-2.33 1.2 0.62-2.33 1.01 0.599-1.69 1.01 0.599-1.69 1.16 0.817-1.64 1.16 0.817-1.64 0.953 0.594-1.53 0.843 1.37 0.884-2.12 0.159 1.31 0.844-2.05 0.227 False False False False Female 174 1730 GRCh37/hg19 P<=5e-07 2020-06-08 prsweb-phecode184-11-phelan-epoc-p-5e-07-mgi-20200608 prsweb-phecode184-11-phelan-epoc-p-5e-07-mgi-20200608 PRSWEB_PHECODE184.11_Phelan-EPOC_P_5e-07_MGI_20200608 P_5e-07 PRSWEB_PHECODE184.11_Phelan-EPOC_P_5e-07_MGI_20200608 184.11 Epithelial ovarian cancer Binary Epithelial ovarian cancer MGI Michigan Genomics Initiative Fixed threshold (5e-07) Phelan CM et al. 2017 28346442 https://www.ncbi.nlm.nih.gov/pubmed/?term=28346442 7 0.94 0.000912008 0.0829 0.5 0.456-0.548 OR 1.33 0.343-5.18 1.33 0.343-5.18 1.26 0.462-3.43 1.26 0.462-3.43 1.42 0.766-2.63 1.42 0.766-2.63 1.45 0.919-2.28 1.45 0.919-2.28 1.05 0.735-1.49 1.05 0.735-1.49 1.07 0.699-1.64 0.75 0.905 0.578-1.42 0.663 1.01 0.656-1.55 0.963 False False False False Female 174 1730 GRCh37/hg19 P<=5e-07 2020-06-08 prsweb-phecode184-11-phelan-ieoc-p-5e-07-mgi-20200608 prsweb-phecode184-11-phelan-ieoc-p-5e-07-mgi-20200608 PRSWEB_PHECODE184.11_Phelan-IEOC_P_5e-07_MGI_20200608 P_5e-07 PRSWEB_PHECODE184.11_Phelan-IEOC_P_5e-07_MGI_20200608 184.11 Invasive epithelial ovarian cancer Binary Invasive epithelial ovarian cancer MGI Michigan Genomics Initiative Fixed threshold (5e-07) Phelan CM et al. 2017 28346442 https://www.ncbi.nlm.nih.gov/pubmed/?term=28346442 23 0.064 0.000652689 0.0828 0.545 0.504-0.589 OR 0 0-0 0 0-0 0.991 0.323-3.04 0.991 0.323-3.04 0.849 0.396-1.82 0.849 0.396-1.82 1.2 0.738-1.95 1.2 0.738-1.95 1.43 1.02-2 1.43 1.02-2 1.27 0.795-2.03 0.317 1.26 0.79-2.01 0.331 1.68 1.07-2.61 0.0227 False False False False Female 174 1730 GRCh37/hg19 P<=5e-07 2020-06-08 prsweb-phecode184-11-phelan-lsasboc-p-5e-07-mgi-20200608 prsweb-phecode184-11-phelan-lsasboc-p-5e-07-mgi-20200608 PRSWEB_PHECODE184.11_Phelan-LSASBOC_P_5e-07_MGI_20200608 P_5e-07 PRSWEB_PHECODE184.11_Phelan-LSASBOC_P_5e-07_MGI_20200608 184.11 Low-grade serous and serous borderline ovarian cancer Binary Low-grade serous and serous borderline ovarian cancer MGI Michigan Genomics Initiative Fixed threshold (5e-07) Phelan CM et al. 2017 28346442 https://www.ncbi.nlm.nih.gov/pubmed/?term=28346442 13 0.82 0.00474436 0.0829 0.511 0.462-0.556 OR 0.804 0.146-4.43 0.804 0.146-4.43 0.692 0.188-2.54 0.692 0.188-2.54 0.964 0.468-1.98 0.964 0.468-1.98 0.872 0.507-1.5 0.872 0.507-1.5 1.31 0.933-1.84 1.31 0.933-1.84 0.956 0.619-1.48 0.839 0.765 0.481-1.22 0.257 1.15 0.762-1.75 0.499 False False False False Female 174 1730 GRCh37/hg19 P<=5e-07 2020-06-08 prsweb-phecode184-11-phelan-mcoc-p-5e-07-mgi-20200608 prsweb-phecode184-11-phelan-mcoc-p-5e-07-mgi-20200608 PRSWEB_PHECODE184.11_Phelan-MCOC_P_5e-07_MGI_20200608 P_5e-07 PRSWEB_PHECODE184.11_Phelan-MCOC_P_5e-07_MGI_20200608 184.11 Mucinous ovarian carcinoma Binary Mucinous ovarian carcinoma MGI Michigan Genomics Initiative Fixed threshold (5e-07) Phelan CM et al. 2017 28346442 https://www.ncbi.nlm.nih.gov/pubmed/?term=28346442 8 0.17 0.00117828 0.0829 0.532 0.487-0.578 OR 2.43 0.84-7.05 2.43 0.84-7.05 2.14 0.95-4.81 2.14 0.95-4.81 1.45 0.782-2.68 1.45 0.782-2.68 0.936 0.551-1.59 0.936 0.551-1.59 1.18 0.835-1.67 1.18 0.835-1.67 1.12 0.711-1.78 0.617 1.27 0.81-1.99 0.298 1.31 0.842-2.04 0.23 False False False False Female 174 1730 GRCh37/hg19 P<=5e-07 2020-06-08 prsweb-phecode184-11-phelan-sioc-p-5e-07-mgi-20200608 prsweb-phecode184-11-phelan-sioc-p-5e-07-mgi-20200608 PRSWEB_PHECODE184.11_Phelan-SIOC_P_5e-07_MGI_20200608 P_5e-07 PRSWEB_PHECODE184.11_Phelan-SIOC_P_5e-07_MGI_20200608 184.11 Serous invasive ovarian cancer Binary Serous invasive ovarian cancer MGI Michigan Genomics Initiative Fixed threshold (5e-07) Phelan CM et al. 2017 28346442 https://www.ncbi.nlm.nih.gov/pubmed/?term=28346442 31 0.033 0.000451538 0.0827 0.548 0.506-0.592 OR 0.801 0.145-4.43 0.801 0.145-4.43 0.976 0.319-2.99 0.976 0.319-2.99 0.951 0.461-1.96 0.951 0.461-1.96 1.38 0.872-2.2 1.38 0.872-2.2 1.38 0.99-1.94 1.38 0.99-1.94 1.61 1-2.58 0.0501 1.42 0.873-2.3 0.159 1.88 1.18-2.98 0.00742 True False False False Female 174 1730 GRCh37/hg19 P<=5e-07 2020-06-08 prsweb-phecode184-11-gwas-catalog-r2019-05-03-x184-11-p-5e-09-mgi-20200608 prsweb-phecode184-11-gwas-catalog-r2019-05-03-x184-11-p-5e-09-mgi-20200608 PRSWEB_PHECODE184.11_GWAS-Catalog-r2019-05-03-X184.11_P_5e-09_MGI_20200608 P_5e-09 PRSWEB_PHECODE184.11_GWAS-Catalog-r2019-05-03-X184.11_P_5e-09_MGI_20200608 184.11 Epithelial ovarian cancer;High-grade serous ovarian cancer;Serous invasive ovarian cancer;Invasive epithelial ovarian cancer;Mucinous ovarian carcinoma;Low-grade serous and serous borderline ovarian cancer;Serous borderline ovarian cancer;Ovarian cancer in BRCA1 mutation carriers;Ovarian cancer;Ovarian clear cell cancer Binary 32 unique SNPs MGI Michigan Genomics Initiative Fixed threshold (5e-09) GWAS Catalog (2019-05-03) 19648919;21964575;23544013;25581431;28346442 https://www.ncbi.nlm.nih.gov/pubmed/?term=19648919+21964575+23544013+25581431+28346442 14 0.27 0.0042369 0.0829 0.526 0.481-0.571 OR 0.803 0.145-4.43 0.803 0.145-4.43 0.688 0.187-2.53 0.688 0.187-2.53 0.84 0.391-1.8 0.84 0.391-1.8 0.994 0.592-1.67 0.994 0.592-1.67 1.15 0.816-1.63 1.15 0.816-1.63 1.76 1.1-2.83 0.0192 1.69 1.05-2.72 0.031 1.7 1.06-2.74 0.0292 False False False False Female 174 1730 GRCh37/hg19 P<=5e-09 2020-06-08 prsweb-phecode184-11-phelan-epoc-p-5e-09-mgi-20200608 prsweb-phecode184-11-phelan-epoc-p-5e-09-mgi-20200608 PRSWEB_PHECODE184.11_Phelan-EPOC_P_5e-09_MGI_20200608 P_5e-09 PRSWEB_PHECODE184.11_Phelan-EPOC_P_5e-09_MGI_20200608 184.11 Epithelial ovarian cancer Binary Epithelial ovarian cancer MGI Michigan Genomics Initiative Fixed threshold (5e-09) Phelan CM et al. 2017 28346442 https://www.ncbi.nlm.nih.gov/pubmed/?term=28346442 5 0.75 0.00770036 0.0829 0.504 0.46-0.551 OR 1.9 0.582-6.23 1.9 0.582-6.23 1.26 0.459-3.46 1.26 0.459-3.46 1.16 0.599-2.25 1.16 0.599-2.25 1.39 0.874-2.2 1.39 0.874-2.2 1.05 0.737-1.5 1.05 0.737-1.5 0.85 0.549-1.32 0.467 0.891 0.578-1.37 0.599 0.939 0.614-1.44 0.773 False False False False Female 174 1730 GRCh37/hg19 P<=5e-09 2020-06-08 prsweb-phecode184-11-phelan-ieoc-p-5e-09-mgi-20200608 prsweb-phecode184-11-phelan-ieoc-p-5e-09-mgi-20200608 PRSWEB_PHECODE184.11_Phelan-IEOC_P_5e-09_MGI_20200608 P_5e-09 PRSWEB_PHECODE184.11_Phelan-IEOC_P_5e-09_MGI_20200608 184.11 Invasive epithelial ovarian cancer Binary Invasive epithelial ovarian cancer MGI Michigan Genomics Initiative Fixed threshold (5e-09) Phelan CM et al. 2017 28346442 https://www.ncbi.nlm.nih.gov/pubmed/?term=28346442 13 0.053 0.000627797 0.0828 0.545 0.5-0.592 OR 1.31 0.337-5.12 1.31 0.337-5.12 0.682 0.185-2.51 0.682 0.185-2.51 1.08 0.539-2.14 1.08 0.539-2.14 1.46 0.928-2.3 1.46 0.928-2.3 1.36 0.971-1.91 1.36 0.971-1.91 1.25 0.785-2 0.343 1.33 0.837-2.12 0.227 1.62 1.04-2.54 0.0338 False False False False Female 174 1730 GRCh37/hg19 P<=5e-09 2020-06-08 prsweb-phecode184-11-phelan-sioc-p-5e-09-mgi-20200608 prsweb-phecode184-11-phelan-sioc-p-5e-09-mgi-20200608 PRSWEB_PHECODE184.11_Phelan-SIOC_P_5e-09_MGI_20200608 P_5e-09 PRSWEB_PHECODE184.11_Phelan-SIOC_P_5e-09_MGI_20200608 184.11 Serous invasive ovarian cancer Binary Serous invasive ovarian cancer MGI Michigan Genomics Initiative Fixed threshold (5e-09) Phelan CM et al. 2017 28346442 https://www.ncbi.nlm.nih.gov/pubmed/?term=28346442 19 0.029 0.000547148 0.0827 0.552 0.506-0.595 OR 1.36 0.349-5.29 1.36 0.349-5.29 1.27 0.467-3.47 1.27 0.467-3.47 1.44 0.776-2.66 1.44 0.776-2.66 1.54 0.982-2.41 1.54 0.982-2.41 1.56 1.12-2.17 1.56 1.12-2.17 1.73 1.08-2.77 0.0222 1.17 0.707-1.93 0.544 2 1.26-3.15 0.00308 True False False False Female 174 1730 GRCh37/hg19 P<=5e-09 2020-06-08 prsweb-phecode184-11-gwas-catalog-r2019-05-03-x184-11-p-5e-08-mgi-20200608 prsweb-phecode184-11-gwas-catalog-r2019-05-03-x184-11-p-5e-08-mgi-20200608 PRSWEB_PHECODE184.11_GWAS-Catalog-r2019-05-03-X184.11_P_5e-08_MGI_20200608 P_5e-08 PRSWEB_PHECODE184.11_GWAS-Catalog-r2019-05-03-X184.11_P_5e-08_MGI_20200608 184.11 Epithelial ovarian cancer;High-grade serous ovarian cancer;Serous invasive ovarian cancer;Invasive epithelial ovarian cancer;Mucinous ovarian carcinoma;Low-grade serous and serous borderline ovarian cancer;Serous borderline ovarian cancer;Ovarian cancer in BRCA1 mutation carriers;Ovarian cancer;Ovarian clear cell cancer Binary 32 unique SNPs MGI Michigan Genomics Initiative GWAS Hits GWAS Catalog (2019-05-03) 19648919;21964575;23544013;25581431;28346442 https://www.ncbi.nlm.nih.gov/pubmed/?term=19648919+21964575+23544013+25581431+28346442 21 0.17 0.00277694 0.0829 0.533 0.485-0.58 OR 1.37 0.351-5.34 1.37 0.351-5.34 0.997 0.325-3.06 0.997 0.325-3.06 1.09 0.547-2.17 1.09 0.547-2.17 1.08 0.648-1.79 1.08 0.648-1.79 1.36 0.974-1.91 1.36 0.974-1.91 0.88 0.541-1.43 0.607 1.37 0.876-2.13 0.168 1.5 0.972-2.33 0.0666 False False False False Female 174 1730 GRCh37/hg19 P<=5e-08 2020-06-08 prsweb-phecode184-11-phelan-epoc-p-5e-08-mgi-20200608 prsweb-phecode184-11-phelan-epoc-p-5e-08-mgi-20200608 PRSWEB_PHECODE184.11_Phelan-EPOC_P_5e-08_MGI_20200608 P_5e-08 PRSWEB_PHECODE184.11_Phelan-EPOC_P_5e-08_MGI_20200608 184.11 Epithelial ovarian cancer Binary Epithelial ovarian cancer MGI Michigan Genomics Initiative GWAS Hits Phelan CM et al. 2017 28346442 https://www.ncbi.nlm.nih.gov/pubmed/?term=28346442 6 0.79 0.00365518 0.0829 0.506 0.461-0.551 OR 1.87 0.571-6.13 1.87 0.571-6.13 1.21 0.442-3.29 1.21 0.442-3.29 1.42 0.763-2.62 1.42 0.763-2.62 1.11 0.677-1.83 1.11 0.677-1.83 1.15 0.809-1.62 1.15 0.809-1.62 1.23 0.8-1.9 0.342 0.938 0.592-1.49 0.786 1.17 0.757-1.8 0.483 False False False False Female 174 1730 GRCh37/hg19 P<=5e-08 2020-06-08 prsweb-phecode184-11-phelan-ieoc-p-5e-08-mgi-20200608 prsweb-phecode184-11-phelan-ieoc-p-5e-08-mgi-20200608 PRSWEB_PHECODE184.11_Phelan-IEOC_P_5e-08_MGI_20200608 P_5e-08 PRSWEB_PHECODE184.11_Phelan-IEOC_P_5e-08_MGI_20200608 184.11 Invasive epithelial ovarian cancer Binary Invasive epithelial ovarian cancer MGI Michigan Genomics Initiative GWAS Hits Phelan CM et al. 2017 28346442 https://www.ncbi.nlm.nih.gov/pubmed/?term=28346442 16 0.079 0.00036208 0.0828 0.542 0.495-0.587 OR 0.787 0.143-4.35 0.787 0.143-4.35 0.691 0.188-2.55 0.691 0.188-2.55 1.46 0.787-2.7 1.46 0.787-2.7 1.32 0.826-2.11 1.32 0.826-2.11 1.51 1.08-2.1 1.51 1.08-2.1 1.26 0.796-2 0.323 1.08 0.674-1.73 0.751 1.61 1.04-2.49 0.0318 False False False False Female 174 1730 GRCh37/hg19 P<=5e-08 2020-06-08 prsweb-phecode184-11-phelan-lsasboc-p-5e-08-mgi-20200608 prsweb-phecode184-11-phelan-lsasboc-p-5e-08-mgi-20200608 PRSWEB_PHECODE184.11_Phelan-LSASBOC_P_5e-08_MGI_20200608 P_5e-08 PRSWEB_PHECODE184.11_Phelan-LSASBOC_P_5e-08_MGI_20200608 184.11 Low-grade serous and serous borderline ovarian cancer Binary Low-grade serous and serous borderline ovarian cancer MGI Michigan Genomics Initiative GWAS Hits Phelan CM et al. 2017 28346442 https://www.ncbi.nlm.nih.gov/pubmed/?term=28346442 10 0.67 0.00636302 0.0829 0.517 0.467-0.562 OR 0.802 0.145-4.42 0.802 0.145-4.42 0.419 0.0802-2.19 0.419 0.0802-2.19 1.07 0.539-2.14 1.07 0.539-2.14 1.25 0.778-2.02 1.25 0.778-2.02 1.29 0.915-1.81 1.29 0.915-1.81 0.734 0.468-1.15 0.178 0.816 0.527-1.26 0.362 1.08 0.716-1.63 0.715 False False False False Female 174 1730 GRCh37/hg19 P<=5e-08 2020-06-08 prsweb-phecode184-11-phelan-mcoc-p-5e-08-mgi-20200608 prsweb-phecode184-11-phelan-mcoc-p-5e-08-mgi-20200608 PRSWEB_PHECODE184.11_Phelan-MCOC_P_5e-08_MGI_20200608 P_5e-08 PRSWEB_PHECODE184.11_Phelan-MCOC_P_5e-08_MGI_20200608 184.11 Mucinous ovarian carcinoma Binary Mucinous ovarian carcinoma MGI Michigan Genomics Initiative GWAS Hits Phelan CM et al. 2017 28346442 https://www.ncbi.nlm.nih.gov/pubmed/?term=28346442 5 0.27 0.000700944 0.0829 0.522 0.474-0.567 OR 2.46 0.848-7.13 2.46 0.848-7.13 1.86 0.785-4.39 1.86 0.785-4.39 1.83 1.04-3.21 1.83 1.04-3.21 1.6 1.03-2.49 1.6 1.03-2.49 1.24 0.883-1.75 1.24 0.883-1.75 1.23 0.784-1.93 0.366 1.13 0.712-1.79 0.61 1.35 0.867-2.09 0.185 False False False False Female 174 1730 GRCh37/hg19 P<=5e-08 2020-06-08 prsweb-phecode184-11-phelan-sioc-p-5e-08-mgi-20200608 prsweb-phecode184-11-phelan-sioc-p-5e-08-mgi-20200608 PRSWEB_PHECODE184.11_Phelan-SIOC_P_5e-08_MGI_20200608 P_5e-08 PRSWEB_PHECODE184.11_Phelan-SIOC_P_5e-08_MGI_20200608 184.11 Serous invasive ovarian cancer Binary Serous invasive ovarian cancer MGI Michigan Genomics Initiative GWAS Hits Phelan CM et al. 2017 28346442 https://www.ncbi.nlm.nih.gov/pubmed/?term=28346442 21 0.031 0.000215534 0.0827 0.554 0.509-0.597 OR 0.784 0.142-4.32 0.784 0.142-4.32 0.969 0.316-2.97 0.969 0.316-2.97 1.2 0.617-2.31 1.2 0.617-2.31 1.75 1.14-2.7 1.75 1.14-2.7 1.55 1.11-2.16 1.55 1.11-2.16 1.73 1.08-2.77 0.0215 1.16 0.701-1.91 0.569 2.02 1.28-3.2 0.00259 True False False True Female 174 1730 GRCh37/hg19 P<=5e-08 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000559/ScoringFiles/ https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000559/ScoringFiles/ /larsf/prsweb-data/cancerprsweb/releases/cancerprsweb_20200608/phewas/PRSWEB_PHECODE184.11_Phelan-SIOC_P_5e-08_MGI_20200608/all.tsv /larsf/prsweb-data/cancerprsweb/releases/cancerprsweb_20200608/phewas/PRSWEB_PHECODE184.11_Phelan-SIOC_P_5e-08_MGI_20200608/exclusion.tsv 2020-06-08 prsweb-phecode184-11-20001-1039-pt-mgi-20200608 prsweb-phecode184-11-20001-1039-pt-mgi-20200608 PRSWEB_PHECODE184.11_20001-1039_PT_MGI_20200608 P&T PRSWEB_PHECODE184.11_20001-1039_PT_MGI_20200608 184.11 Cancer code, self-reported: ovarian cancer Binary GWAS round 2: Results shared 1st August 2018. Imputed genotypes from HRC plus UK10K & 1000 Genomes reference panels as released by UK Biobank in March 2018. MGI Michigan Genomics Initiative P&T UKB GWAS (PHESANT) UKB_GWAS https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761 34 0.22 0.00373365 0.0829 0.518 0.473-0.562 OR 1.3 0.334-5.07 1.3 0.334-5.07 1.78 0.754-4.22 1.78 0.754-4.22 1.41 0.757-2.61 1.41 0.757-2.61 1.23 0.762-1.99 1.23 0.762-1.99 1.18 0.833-1.66 1.18 0.833-1.66 0.852 0.535-1.36 0.5 1.21 0.788-1.87 0.38 1.21 0.784-1.86 0.39 False False False False Female 174 1730 GRCh37/hg19 P<=1.58e-05 2020-06-08 prsweb-phecode184-11-c3-ovary-pt-mgi-20200608 prsweb-phecode184-11-c3-ovary-pt-mgi-20200608 PRSWEB_PHECODE184.11_C3-OVARY_PT_MGI_20200608 P&T PRSWEB_PHECODE184.11_C3-OVARY_PT_MGI_20200608 184.11 Malignant neoplasm of ovary Binary GWAS round 2: Results shared 1st August 2018. Imputed genotypes from HRC plus UK10K & 1000 Genomes reference panels as released by UK Biobank in March 2018. MGI Michigan Genomics Initiative P&T UKB GWAS (FINNGEN) UKB_GWAS https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761 193 0.53 0.000915249 0.0829 0.513 0.469-0.556 OR 0.826 0.15-4.56 0.826 0.15-4.56 0.993 0.325-3.04 0.993 0.325-3.04 0.958 0.465-1.97 0.958 0.465-1.97 0.99 0.59-1.66 0.99 0.59-1.66 1.09 0.765-1.54 1.09 0.765-1.54 1.11 0.71-1.73 0.652 1.15 0.737-1.79 0.542 1.18 0.756-1.83 0.472 False False False False Female 174 1730 GRCh37/hg19 P<=9.99e-05 2020-06-08 prsweb-phecode184-11-c56-pt-mgi-20200608 prsweb-phecode184-11-c56-pt-mgi-20200608 PRSWEB_PHECODE184.11_C56_PT_MGI_20200608 P&T PRSWEB_PHECODE184.11_C56_PT_MGI_20200608 184.11 Diagnoses - main ICD10: C56 Malignant neoplasm of ovary Binary GWAS round 2: Results shared 1st August 2018. Imputed genotypes from HRC plus UK10K & 1000 Genomes reference panels as released by UK Biobank in March 2018. MGI Michigan Genomics Initiative P&T UKB GWAS (ICD10) UKB_GWAS https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761 14 0.18 0.00163533 0.0828 0.519 0.475-0.563 OR 1.91 0.587-6.22 1.91 0.587-6.22 1.28 0.469-3.49 1.28 0.469-3.49 1.35 0.713-2.55 1.35 0.713-2.55 1.25 0.778-2.02 1.25 0.778-2.02 1.18 0.834-1.66 1.18 0.834-1.66 0.918 0.571-1.48 0.726 1.45 0.936-2.24 0.0967 1.33 0.856-2.07 0.204 False False False False Female 174 1730 GRCh37/hg19 P<=7.94e-06 2020-06-08 prsweb-phecode184-11-gwas-catalog-r2019-05-03-x184-11-pt-mgi-20200608 prsweb-phecode184-11-gwas-catalog-r2019-05-03-x184-11-pt-mgi-20200608 PRSWEB_PHECODE184.11_GWAS-Catalog-r2019-05-03-X184.11_PT_MGI_20200608 P&T PRSWEB_PHECODE184.11_GWAS-Catalog-r2019-05-03-X184.11_PT_MGI_20200608 184.11 Epithelial ovarian cancer;High-grade serous ovarian cancer;Serous invasive ovarian cancer;Invasive epithelial ovarian cancer;Mucinous ovarian carcinoma;Low-grade serous and serous borderline ovarian cancer;Serous borderline ovarian cancer;Ovarian cancer in BRCA1 mutation carriers;Ovarian cancer;Ovarian clear cell cancer Binary 32 unique SNPs MGI Michigan Genomics Initiative P&T GWAS Catalog (2019-05-03) 19648919;21964575;23544013;25581431;28346442 https://www.ncbi.nlm.nih.gov/pubmed/?term=19648919+21964575+23544013+25581431+28346442 10 0.6 0.00611158 0.0829 0.505 0.459-0.549 OR 0.799 0.145-4.41 0.799 0.145-4.41 0.69 0.187-2.54 0.69 0.187-2.54 1.19 0.613-2.3 1.19 0.613-2.3 1.13 0.689-1.86 1.13 0.689-1.86 0.991 0.692-1.42 0.991 0.692-1.42 1.4 0.891-2.21 0.144 1.43 0.907-2.24 0.124 1.26 0.791-1.99 0.335 False False False False Female 174 1730 GRCh37/hg19 P<=5e-10 2020-06-08 prsweb-phecode184-11-phelan-epoc-pt-mgi-20200608 prsweb-phecode184-11-phelan-epoc-pt-mgi-20200608 PRSWEB_PHECODE184.11_Phelan-EPOC_PT_MGI_20200608 P&T PRSWEB_PHECODE184.11_Phelan-EPOC_PT_MGI_20200608 184.11 Epithelial ovarian cancer Binary Epithelial ovarian cancer MGI Michigan Genomics Initiative P&T Phelan CM et al. 2017 28346442 https://www.ncbi.nlm.nih.gov/pubmed/?term=28346442 5 0.75 0.00770036 0.0829 0.504 0.46-0.551 OR 1.9 0.582-6.23 1.9 0.582-6.23 1.26 0.459-3.46 1.26 0.459-3.46 1.16 0.599-2.25 1.16 0.599-2.25 1.39 0.874-2.2 1.39 0.874-2.2 1.05 0.737-1.5 1.05 0.737-1.5 0.85 0.549-1.32 0.467 0.891 0.578-1.37 0.599 0.939 0.614-1.44 0.773 False False False False Female 174 1730 GRCh37/hg19 P<=2e-10 2020-06-08 prsweb-phecode184-11-phelan-hsoc-pt-mgi-20200608 prsweb-phecode184-11-phelan-hsoc-pt-mgi-20200608 PRSWEB_PHECODE184.11_Phelan-HSOC_PT_MGI_20200608 P&T PRSWEB_PHECODE184.11_Phelan-HSOC_PT_MGI_20200608 184.11 High-grade serous ovarian cancer Binary High-grade serous ovarian cancer MGI Michigan Genomics Initiative P&T Phelan CM et al. 2017 28346442 https://www.ncbi.nlm.nih.gov/pubmed/?term=28346442 9 0.38 0.0014091 0.0829 0.52 0.48-0.56 OR 0.774 0.14-4.27 0.774 0.14-4.27 0.957 0.313-2.93 0.957 0.313-2.93 0.606 0.252-1.45 0.606 0.252-1.45 0.937 0.552-1.59 0.937 0.552-1.59 1.24 0.884-1.75 1.24 0.884-1.75 1.38 0.898-2.12 0.141 0.777 0.479-1.26 0.306 1.27 0.819-1.96 0.289 False False False False Female 174 1730 GRCh37/hg19 P<=3.98e-06 2020-06-08 prsweb-phecode184-11-phelan-ieoc-pt-mgi-20200608 prsweb-phecode184-11-phelan-ieoc-pt-mgi-20200608 PRSWEB_PHECODE184.11_Phelan-IEOC_PT_MGI_20200608 P&T PRSWEB_PHECODE184.11_Phelan-IEOC_PT_MGI_20200608 184.11 Invasive epithelial ovarian cancer Binary Invasive epithelial ovarian cancer MGI Michigan Genomics Initiative P&T Phelan CM et al. 2017 28346442 https://www.ncbi.nlm.nih.gov/pubmed/?term=28346442 144 0.28 0.00147311 0.0829 0.535 0.495-0.577 OR 0 0-0 0 0-0 0.137 0.00818-2.29 0.137 0.00818-2.29 0.5 0.191-1.31 0.5 0.191-1.31 0.693 0.382-1.26 0.693 0.382-1.26 1.25 0.886-1.76 1.25 0.886-1.76 1.37 0.869-2.16 0.176 1.22 0.77-1.95 0.393 1.48 0.949-2.32 0.0837 False False False False Female 174 1730 GRCh37/hg19 P<=2.51e-05 2020-06-08 prsweb-phecode184-11-phelan-lsasboc-pt-mgi-20200608 prsweb-phecode184-11-phelan-lsasboc-pt-mgi-20200608 PRSWEB_PHECODE184.11_Phelan-LSASBOC_PT_MGI_20200608 P&T PRSWEB_PHECODE184.11_Phelan-LSASBOC_PT_MGI_20200608 184.11 Low-grade serous and serous borderline ovarian cancer Binary Low-grade serous and serous borderline ovarian cancer MGI Michigan Genomics Initiative P&T Phelan CM et al. 2017 28346442 https://www.ncbi.nlm.nih.gov/pubmed/?term=28346442 34 0.31 0.00952796 0.0829 0.527 0.485-0.569 OR 0 0-0 0 0-0 0.41 0.0786-2.14 0.41 0.0786-2.14 0.607 0.253-1.45 0.607 0.253-1.45 1.06 0.637-1.75 1.06 0.637-1.75 1.15 0.814-1.63 1.15 0.814-1.63 1.02 0.652-1.6 0.929 1.13 0.725-1.75 0.594 1.19 0.769-1.83 0.439 False False False False Female 174 1730 GRCh37/hg19 P<=6.31e-06 2020-06-08 prsweb-phecode184-11-phelan-lsoc-pt-mgi-20200608 prsweb-phecode184-11-phelan-lsoc-pt-mgi-20200608 PRSWEB_PHECODE184.11_Phelan-LSOC_PT_MGI_20200608 P&T PRSWEB_PHECODE184.11_Phelan-LSOC_PT_MGI_20200608 184.11 Low-grade serous ovarian cancer Binary Low-grade serous ovarian cancer MGI Michigan Genomics Initiative P&T Phelan CM et al. 2017 28346442 https://www.ncbi.nlm.nih.gov/pubmed/?term=28346442 176 0.58 0.00208921 0.0829 0.521 0.475-0.565 OR 0.792 0.143-4.38 0.792 0.143-4.38 0.688 0.187-2.53 0.688 0.187-2.53 0.829 0.387-1.78 0.829 0.387-1.78 0.921 0.542-1.57 0.921 0.542-1.57 1.2 0.854-1.7 1.2 0.854-1.7 1.14 0.729-1.79 0.56 1.14 0.726-1.78 0.573 1.25 0.807-1.94 0.315 False False False False Female 174 1730 GRCh37/hg19 P<=9.99e-05 2020-06-08 prsweb-phecode184-11-phelan-mcoc-pt-mgi-20200608 prsweb-phecode184-11-phelan-mcoc-pt-mgi-20200608 PRSWEB_PHECODE184.11_Phelan-MCOC_PT_MGI_20200608 P&T PRSWEB_PHECODE184.11_Phelan-MCOC_PT_MGI_20200608 184.11 Mucinous ovarian carcinoma Binary Mucinous ovarian carcinoma MGI Michigan Genomics Initiative P&T Phelan CM et al. 2017 28346442 https://www.ncbi.nlm.nih.gov/pubmed/?term=28346442 254 0.72 0.00541796 0.0829 0.509 0.463-0.554 OR 1.84 0.564-5.98 1.84 0.564-5.98 1.53 0.608-3.84 1.53 0.608-3.84 1.3 0.69-2.46 1.3 0.69-2.46 1.18 0.725-1.92 1.18 0.725-1.92 1.08 0.76-1.54 1.08 0.76-1.54 0.857 0.548-1.34 0.498 0.98 0.636-1.51 0.925 1.02 0.664-1.56 0.934 False False False False Female 174 1730 GRCh37/hg19 P<=1e-04 2020-06-08 prsweb-phecode184-11-phelan-sioc-pt-mgi-20200608 prsweb-phecode184-11-phelan-sioc-pt-mgi-20200608 PRSWEB_PHECODE184.11_Phelan-SIOC_PT_MGI_20200608 P&T PRSWEB_PHECODE184.11_Phelan-SIOC_PT_MGI_20200608 184.11 Serous invasive ovarian cancer Binary Serous invasive ovarian cancer MGI Michigan Genomics Initiative P&T Phelan CM et al. 2017 28346442 https://www.ncbi.nlm.nih.gov/pubmed/?term=28346442 104 0.28 0.00678385 0.0829 0.528 0.486-0.569 OR 0.783 0.142-4.32 0.783 0.142-4.32 0.677 0.184-2.5 0.677 0.184-2.5 0.606 0.253-1.46 0.606 0.253-1.46 0.939 0.553-1.59 0.939 0.553-1.59 1.06 0.746-1.51 1.06 0.746-1.51 1.22 0.774-1.94 0.387 1.4 0.897-2.19 0.138 1.29 0.818-2.04 0.273 False False False False Female 174 1730 GRCh37/hg19 P<=1.58e-05 2020-06-08 prsweb-phecode184-11-20001-1039-prs-cs-mgi-20200608 prsweb-phecode184-11-20001-1039-prs-cs-mgi-20200608 PRSWEB_PHECODE184.11_20001-1039_PRS-CS_MGI_20200608 PRS-CS PRSWEB_PHECODE184.11_20001-1039_PRS-CS_MGI_20200608 184.11 Cancer code, self-reported: ovarian cancer Binary GWAS round 2: Results shared 1st August 2018. Imputed genotypes from HRC plus UK10K & 1000 Genomes reference panels as released by UK Biobank in March 2018. MGI Michigan Genomics Initiative PRS-CS UKB GWAS (PHESANT) UKB_GWAS https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761 1082696 0.22 0.000358723 0.0829 0.529 0.483-0.57 OR 0.737 0.133-4.07 0.737 0.133-4.07 0.924 0.301-2.83 0.924 0.301-2.83 1.05 0.524-2.09 1.05 0.524-2.09 1.24 0.772-2.01 1.24 0.772-2.01 1.24 0.88-1.74 1.24 0.88-1.74 1.05 0.671-1.66 0.82 1.03 0.657-1.61 0.903 1.27 0.828-1.95 0.271 False False False False Female 174 1730 GRCh37/hg19 auto 2020-06-08 prsweb-phecode184-11-c3-ovary-prs-cs-mgi-20200608 prsweb-phecode184-11-c3-ovary-prs-cs-mgi-20200608 PRSWEB_PHECODE184.11_C3-OVARY_PRS-CS_MGI_20200608 PRS-CS PRSWEB_PHECODE184.11_C3-OVARY_PRS-CS_MGI_20200608 184.11 Malignant neoplasm of ovary Binary GWAS round 2: Results shared 1st August 2018. Imputed genotypes from HRC plus UK10K & 1000 Genomes reference panels as released by UK Biobank in March 2018. MGI Michigan Genomics Initiative PRS-CS UKB GWAS (FINNGEN) UKB_GWAS https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761 1095247 0.4 0.00274019 0.0829 0.525 0.478-0.568 OR 1.26 0.323-4.94 1.26 0.323-4.94 1.21 0.444-3.32 1.21 0.444-3.32 1.43 0.775-2.66 1.43 0.775-2.66 1.12 0.685-1.85 1.12 0.685-1.85 1.25 0.89-1.76 1.25 0.89-1.76 1.03 0.657-1.61 0.898 1.04 0.664-1.63 0.868 1.25 0.81-1.92 0.317 False False False False Female 174 1730 GRCh37/hg19 auto 2020-06-08 prsweb-phecode184-11-c56-prs-cs-mgi-20200608 prsweb-phecode184-11-c56-prs-cs-mgi-20200608 PRSWEB_PHECODE184.11_C56_PRS-CS_MGI_20200608 PRS-CS PRSWEB_PHECODE184.11_C56_PRS-CS_MGI_20200608 184.11 Diagnoses - main ICD10: C56 Malignant neoplasm of ovary Binary GWAS round 2: Results shared 1st August 2018. Imputed genotypes from HRC plus UK10K & 1000 Genomes reference panels as released by UK Biobank in March 2018. MGI Michigan Genomics Initiative PRS-CS UKB GWAS (ICD10) UKB_GWAS https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761 1091510 0.57 6.33438e-05 0.0829 0.518 0.474-0.56 OR 3.09 1.15-8.29 3.09 1.15-8.29 1.57 0.624-3.93 1.57 0.624-3.93 0.84 0.392-1.8 0.84 0.392-1.8 0.631 0.341-1.17 0.631 0.341-1.17 1.15 0.811-1.62 1.15 0.811-1.62 1.37 0.867-2.16 0.178 1.37 0.858-2.17 0.189 1.4 0.888-2.21 0.147 False False False False Female 174 1730 GRCh37/hg19 auto 2020-06-08 prsweb-phecode184-11-phelan-enoc-prs-cs-mgi-20200608 prsweb-phecode184-11-phelan-enoc-prs-cs-mgi-20200608 PRSWEB_PHECODE184.11_Phelan-ENOC_PRS-CS_MGI_20200608 PRS-CS PRSWEB_PHECODE184.11_Phelan-ENOC_PRS-CS_MGI_20200608 184.11 Endometrioid ovarian cancer Binary Endometrioid ovarian cancer MGI Michigan Genomics Initiative PRS-CS Phelan CM et al. 2017 28346442 https://www.ncbi.nlm.nih.gov/pubmed/?term=28346442 1114056 0.41 3.26737e-06 0.0829 0.523 0.479-0.573 OR 2.49 0.858-7.24 2.49 0.858-7.24 1.6 0.635-4.03 1.6 0.635-4.03 1.57 0.864-2.85 1.57 0.864-2.85 1.13 0.688-1.85 1.13 0.688-1.85 1.15 0.812-1.63 1.15 0.812-1.63 0.773 0.485-1.23 0.277 1.12 0.729-1.71 0.61 1.1 0.718-1.69 0.658 False False False False Female 174 1730 GRCh37/hg19 auto 2020-06-08 prsweb-phecode184-11-phelan-ieoc-prs-cs-mgi-20200608 prsweb-phecode184-11-phelan-ieoc-prs-cs-mgi-20200608 PRSWEB_PHECODE184.11_Phelan-IEOC_PRS-CS_MGI_20200608 PRS-CS PRSWEB_PHECODE184.11_Phelan-IEOC_PRS-CS_MGI_20200608 184.11 Invasive epithelial ovarian cancer Binary Invasive epithelial ovarian cancer MGI Michigan Genomics Initiative PRS-CS Phelan CM et al. 2017 28346442 https://www.ncbi.nlm.nih.gov/pubmed/?term=28346442 1114056 0.14 0.00196861 0.0828 0.537 0.494-0.582 OR 1.87 0.576-6.07 1.87 0.576-6.07 0.973 0.318-2.98 0.973 0.318-2.98 1.45 0.785-2.69 1.45 0.785-2.69 0.939 0.553-1.6 0.939 0.553-1.6 1.22 0.863-1.71 1.22 0.863-1.71 1.15 0.729-1.82 0.543 1.25 0.793-1.96 0.338 1.38 0.888-2.15 0.152 False False False False Female 174 1730 GRCh37/hg19 auto 2020-06-08 prsweb-phecode184-11-phelan-lsasboc-prs-cs-mgi-20200608 prsweb-phecode184-11-phelan-lsasboc-prs-cs-mgi-20200608 PRSWEB_PHECODE184.11_Phelan-LSASBOC_PRS-CS_MGI_20200608 PRS-CS PRSWEB_PHECODE184.11_Phelan-LSASBOC_PRS-CS_MGI_20200608 184.11 Low-grade serous and serous borderline ovarian cancer Binary Low-grade serous and serous borderline ovarian cancer MGI Michigan Genomics Initiative PRS-CS Phelan CM et al. 2017 28346442 https://www.ncbi.nlm.nih.gov/pubmed/?term=28346442 1114056 0.36 0.000388824 0.0829 0.528 0.482-0.572 OR 1.36 0.348-5.29 1.36 0.348-5.29 0.701 0.191-2.58 0.701 0.191-2.58 0.716 0.318-1.61 0.716 0.318-1.61 0.985 0.587-1.65 0.985 0.587-1.65 1 0.703-1.44 1 0.703-1.44 1.15 0.723-1.84 0.551 1.46 0.947-2.27 0.0866 1.19 0.753-1.87 0.459 False False False False Female 174 1730 GRCh37/hg19 auto 2020-06-08 prsweb-phecode184-11-phelan-lsoc-prs-cs-mgi-20200608 prsweb-phecode184-11-phelan-lsoc-prs-cs-mgi-20200608 PRSWEB_PHECODE184.11_Phelan-LSOC_PRS-CS_MGI_20200608 PRS-CS PRSWEB_PHECODE184.11_Phelan-LSOC_PRS-CS_MGI_20200608 184.11 Low-grade serous ovarian cancer Binary Low-grade serous ovarian cancer MGI Michigan Genomics Initiative PRS-CS Phelan CM et al. 2017 28346442 https://www.ncbi.nlm.nih.gov/pubmed/?term=28346442 1114046 0.71 0.000316528 0.0829 0.51 0.467-0.558 OR 2.38 0.819-6.89 2.38 0.819-6.89 1.25 0.458-3.4 1.25 0.458-3.4 1.07 0.536-2.13 1.07 0.536-2.13 0.746 0.419-1.33 0.746 0.419-1.33 0.958 0.668-1.38 0.958 0.668-1.38 0.964 0.612-1.52 0.874 1.32 0.86-2.02 0.205 1.04 0.663-1.62 0.873 False False False False Female 174 1730 GRCh37/hg19 auto 2020-06-08 prsweb-phecode184-11-phelan-mcoc-prs-cs-mgi-20200608 prsweb-phecode184-11-phelan-mcoc-prs-cs-mgi-20200608 PRSWEB_PHECODE184.11_Phelan-MCOC_PRS-CS_MGI_20200608 PRS-CS PRSWEB_PHECODE184.11_Phelan-MCOC_PRS-CS_MGI_20200608 184.11 Mucinous ovarian carcinoma Binary Mucinous ovarian carcinoma MGI Michigan Genomics Initiative PRS-CS Phelan CM et al. 2017 28346442 https://www.ncbi.nlm.nih.gov/pubmed/?term=28346442 1114056 0.7 6.51556e-05 0.0829 0.507 0.462-0.553 OR 1.3 0.333-5.07 1.3 0.333-5.07 0.938 0.305-2.88 0.938 0.305-2.88 1.16 0.599-2.26 1.16 0.599-2.26 1.37 0.865-2.18 1.37 0.865-2.18 0.893 0.619-1.29 0.893 0.619-1.29 1.34 0.866-2.07 0.19 1.19 0.762-1.87 0.441 1.02 0.647-1.62 0.925 False False False False Female 174 1730 GRCh37/hg19 auto 2020-06-08 prsweb-phecode184-11-phelan-sioc-prs-cs-mgi-20200608 prsweb-phecode184-11-phelan-sioc-prs-cs-mgi-20200608 PRSWEB_PHECODE184.11_Phelan-SIOC_PRS-CS_MGI_20200608 PRS-CS PRSWEB_PHECODE184.11_Phelan-SIOC_PRS-CS_MGI_20200608 184.11 Serous invasive ovarian cancer Binary Serous invasive ovarian cancer MGI Michigan Genomics Initiative PRS-CS Phelan CM et al. 2017 28346442 https://www.ncbi.nlm.nih.gov/pubmed/?term=28346442 1114056 0.036 0.00189205 0.0827 0.552 0.513-0.598 OR 0 0-0 0 0-0 0.69 0.187-2.54 0.69 0.187-2.54 1.69 0.949-3.02 1.69 0.949-3.02 1.33 0.829-2.12 1.33 0.829-2.12 1.42 1.02-1.98 1.42 1.02-1.98 1.36 0.853-2.18 0.196 1.28 0.798-2.06 0.304 1.72 1.1-2.7 0.0177 True False False True Female 174 1730 GRCh37/hg19 auto https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000561/ScoringFiles/ https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000561/ScoringFiles/ /larsf/prsweb-data/cancerprsweb/releases/cancerprsweb_20200608/phewas/PRSWEB_PHECODE184.11_Phelan-SIOC_PRS-CS_MGI_20200608/all.tsv /larsf/prsweb-data/cancerprsweb/releases/cancerprsweb_20200608/phewas/PRSWEB_PHECODE184.11_Phelan-SIOC_PRS-CS_MGI_20200608/exclusion.tsv 2020-06-08 prsweb-phecode184-11-20001-1039-lassosum-mgi-20200608 prsweb-phecode184-11-20001-1039-lassosum-mgi-20200608 PRSWEB_PHECODE184.11_20001-1039_LASSOSUM_MGI_20200608 Lassosum PRSWEB_PHECODE184.11_20001-1039_LASSOSUM_MGI_20200608 184.11 Cancer code, self-reported: ovarian cancer Binary GWAS round 2: Results shared 1st August 2018. Imputed genotypes from HRC plus UK10K & 1000 Genomes reference panels as released by UK Biobank in March 2018. MGI Michigan Genomics Initiative lassosum UKB GWAS (PHESANT) UKB_GWAS https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761 214 0.17 0.00181022 0.0829 0.531 0.485-0.573 OR 4.14 1.72-9.98 4.14 1.72-9.98 2.76 1.32-5.8 2.76 1.32-5.8 1.31 0.693-2.48 1.31 0.693-2.48 1.12 0.683-1.84 1.12 0.683-1.84 1.02 0.716-1.46 1.02 0.716-1.46 1.33 0.835-2.11 0.231 1.63 1.04-2.56 0.0343 1.35 0.847-2.15 0.207 False False False False Female 174 1730 GRCh37/hg19 s=0.2;Lambda=0.07848 2020-06-08 prsweb-phecode184-11-c56-lassosum-mgi-20200608 prsweb-phecode184-11-c56-lassosum-mgi-20200608 PRSWEB_PHECODE184.11_C56_LASSOSUM_MGI_20200608 Lassosum PRSWEB_PHECODE184.11_C56_LASSOSUM_MGI_20200608 184.11 Diagnoses - main ICD10: C56 Malignant neoplasm of ovary Binary GWAS round 2: Results shared 1st August 2018. Imputed genotypes from HRC plus UK10K & 1000 Genomes reference panels as released by UK Biobank in March 2018. MGI Michigan Genomics Initiative lassosum UKB GWAS (ICD10) UKB_GWAS https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761 49464 0.94 0.000902898 0.0829 0.499 0.457-0.54 OR 0.82 0.148-4.54 0.82 0.148-4.54 0.422 0.0805-2.21 0.422 0.0805-2.21 0.967 0.469-1.99 0.967 0.469-1.99 0.875 0.508-1.51 0.875 0.508-1.51 0.876 0.605-1.27 0.876 0.605-1.27 1.5 0.972-2.31 0.0673 1.18 0.746-1.85 0.485 1.04 0.652-1.64 0.882 False False False False Female 174 1730 GRCh37/hg19 s=0.2;Lambda=0.03793 2020-06-08 prsweb-phecode184-11-phelan-epoc-lassosum-mgi-20200608 prsweb-phecode184-11-phelan-epoc-lassosum-mgi-20200608 PRSWEB_PHECODE184.11_Phelan-EPOC_LASSOSUM_MGI_20200608 Lassosum PRSWEB_PHECODE184.11_Phelan-EPOC_LASSOSUM_MGI_20200608 184.11 Epithelial ovarian cancer Binary Epithelial ovarian cancer MGI Michigan Genomics Initiative lassosum Phelan CM et al. 2017 28346442 https://www.ncbi.nlm.nih.gov/pubmed/?term=28346442 59 0.36 0.00562222 0.0829 0.552 0.511-0.593 OR 0 0-0 0 0-0 0.412 0.0787-2.16 0.412 0.0787-2.16 0.834 0.388-1.79 0.834 0.388-1.79 1.05 0.636-1.75 1.05 0.636-1.75 1.18 0.839-1.67 1.18 0.839-1.67 1.13 0.721-1.78 0.592 1.13 0.719-1.77 0.596 1.3 0.836-2.02 0.246 False False False False Female 174 1730 GRCh37/hg19 s=1;Lambda=0.02336 2020-06-08 prsweb-phecode184-11-phelan-hsoc-lassosum-mgi-20200608 prsweb-phecode184-11-phelan-hsoc-lassosum-mgi-20200608 PRSWEB_PHECODE184.11_Phelan-HSOC_LASSOSUM_MGI_20200608 Lassosum PRSWEB_PHECODE184.11_Phelan-HSOC_LASSOSUM_MGI_20200608 184.11 High-grade serous ovarian cancer Binary High-grade serous ovarian cancer MGI Michigan Genomics Initiative lassosum Phelan CM et al. 2017 28346442 https://www.ncbi.nlm.nih.gov/pubmed/?term=28346442 20012 0.42 0.00490468 0.0829 0.516 0.475-0.56 OR 0.824 0.149-4.55 0.824 0.149-4.55 0.693 0.189-2.55 0.693 0.189-2.55 0.723 0.321-1.63 0.723 0.321-1.63 0.812 0.465-1.42 0.812 0.465-1.42 0.815 0.56-1.19 0.815 0.56-1.19 1.67 1.06-2.64 0.0269 1.67 1.05-2.63 0.0287 1.18 0.726-1.92 0.502 False False False False Female 174 1730 GRCh37/hg19 s=0.9;Lambda=0.01438 2020-06-08 prsweb-phecode184-11-phelan-lsasboc-lassosum-mgi-20200608 prsweb-phecode184-11-phelan-lsasboc-lassosum-mgi-20200608 PRSWEB_PHECODE184.11_Phelan-LSASBOC_LASSOSUM_MGI_20200608 Lassosum PRSWEB_PHECODE184.11_Phelan-LSASBOC_LASSOSUM_MGI_20200608 184.11 Low-grade serous and serous borderline ovarian cancer Binary Low-grade serous and serous borderline ovarian cancer MGI Michigan Genomics Initiative lassosum Phelan CM et al. 2017 28346442 https://www.ncbi.nlm.nih.gov/pubmed/?term=28346442 5328 0.061 0.00907415 0.0827 0.544 0.497-0.589 OR 2.32 0.796-6.76 2.32 0.796-6.76 2.05 0.908-4.64 2.05 0.908-4.64 1.07 0.536-2.12 1.07 0.536-2.12 1.13 0.688-1.85 1.13 0.688-1.85 1.25 0.89-1.77 1.25 0.89-1.77 1.13 0.707-1.8 0.615 1.38 0.881-2.17 0.159 1.39 0.892-2.18 0.145 False False False False Female 174 1730 GRCh37/hg19 s=0.5;Lambda=0.02976 2020-06-08 prsweb-phecode184-11-phelan-occc-lassosum-mgi-20200608 prsweb-phecode184-11-phelan-occc-lassosum-mgi-20200608 PRSWEB_PHECODE184.11_Phelan-OCCC_LASSOSUM_MGI_20200608 Lassosum PRSWEB_PHECODE184.11_Phelan-OCCC_LASSOSUM_MGI_20200608 184.11 Ovarian clear cell cancer Binary Ovarian clear cell cancer MGI Michigan Genomics Initiative lassosum Phelan CM et al. 2017 28346442 https://www.ncbi.nlm.nih.gov/pubmed/?term=28346442 3387 0.074 0.00683928 0.0828 0.539 0.495-0.586 OR 3.04 1.13-8.13 3.04 1.13-8.13 2.46 1.14-5.34 2.46 1.14-5.34 1.6 0.882-2.92 1.6 0.882-2.92 1.57 1-2.46 1.57 1-2.46 1.33 0.946-1.86 1.33 0.946-1.86 0.783 0.481-1.28 0.326 1.36 0.881-2.09 0.166 1.37 0.893-2.11 0.148 False False False False Female 174 1730 GRCh37/hg19 s=1;Lambda=0.04833 2020-06-08