prs_id slug legacy_id legacy_model prswebprefix trait_code trait_name trait_type description cohort cohort_label method gwas_source reference_label reference_url snp_count p_value pseudo_r2 brier_score mse aauc aauc_ci effect_metric top_effect_1 top_effect_1_ci top_or_1 top_or_1_ci top_effect_2 top_effect_2_ci top_or_2 top_or_2_ci top_effect_5 top_effect_5_ci top_or_5 top_or_5_ci top_effect_10 top_effect_10_ci top_or_10 top_or_10_ci top_effect_25 top_effect_25_ci top_or_25 top_or_25_ci q1_vs_q2_effect q1_vs_q2_effect_ci q1_vs_q2_p_value q1_vs_q3_effect q1_vs_q3_effect_ci q1_vs_q3_p_value q1_vs_q4_effect q1_vs_q4_effect_ci q1_vs_q4_p_value nominally_significant reversed_effect_warning underpowered_warning upload_to_portal sex cases controls genome_build tuning_parameter weights_external_url weights_url phewas_download_url exclusion_download_url last_updated prsweb-phecode189-11-c3-kidney-notrenalpelvis-p-5e-05-mgi-20200608 prsweb-phecode189-11-c3-kidney-notrenalpelvis-p-5e-05-mgi-20200608 PRSWEB_PHECODE189.11_C3-KIDNEY-NOTRENALPELVIS_P_5e-05_MGI_20200608 P_5e-05 PRSWEB_PHECODE189.11_C3-KIDNEY-NOTRENALPELVIS_P_5e-05_MGI_20200608 189.11 Malignant neoplasm of kidney, except renal pelvis Binary GWAS round 2: Results shared 1st August 2018. Imputed genotypes from HRC plus UK10K & 1000 Genomes reference panels as released by UK Biobank in March 2018. MGI Michigan Genomics Initiative Fixed threshold (5e-05) UKB GWAS (FINNGEN) UKB_GWAS https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761 132 0.28 1.80826e-07 0.0827 0.511 0.485-0.536 OR 1.03 0.425-2.51 1.03 0.425-2.51 0.97 0.511-1.84 0.97 0.511-1.84 0.907 0.594-1.39 0.907 0.594-1.39 1.01 0.755-1.36 1.01 0.755-1.36 1.12 0.92-1.37 1.12 0.92-1.37 0.938 0.723-1.22 0.627 1.11 0.863-1.42 0.421 1.14 0.887-1.46 0.312 False False False False Both 536 5353 GRCh37/hg19 P<=5e-05 2020-06-08 prsweb-phecode189-11-gwas-catalog-r2019-05-03-x189-11-p-5e-05-mgi-20200608 prsweb-phecode189-11-gwas-catalog-r2019-05-03-x189-11-p-5e-05-mgi-20200608 PRSWEB_PHECODE189.11_GWAS-Catalog-r2019-05-03-X189.11_P_5e-05_MGI_20200608 P_5e-05 PRSWEB_PHECODE189.11_GWAS-Catalog-r2019-05-03-X189.11_P_5e-05_MGI_20200608 189.11 Renal cell carcinoma;Wilms tumor Binary 15 unique SNPs MGI Michigan Genomics Initiative Fixed threshold (5e-05) GWAS Catalog (2019-05-03) 22544364;28598434 https://www.ncbi.nlm.nih.gov/pubmed/?term=22544364+28598434 13 0.17 0.000695805 0.0827 0.492 0.466-0.516 OR 1.78 0.882-3.59 1.78 0.882-3.59 1.15 0.634-2.08 1.15 0.634-2.08 1.49 1.06-2.11 1.49 1.06-2.11 1.24 0.946-1.64 1.24 0.946-1.64 1.06 0.864-1.29 1.06 0.864-1.29 1.11 0.863-1.43 0.415 1.06 0.821-1.37 0.651 1.12 0.872-1.45 0.368 False False False False Both 536 5353 GRCh37/hg19 P<=5e-05 2020-06-08 prsweb-phecode189-11-ukbb-saige-hrc-x189-11-p-5e-05-mgi-20200608 prsweb-phecode189-11-ukbb-saige-hrc-x189-11-p-5e-05-mgi-20200608 PRSWEB_PHECODE189.11_UKBB-SAIGE-HRC-X189.11_P_5e-05_MGI_20200608 P_5e-05 PRSWEB_PHECODE189.11_UKBB-SAIGE-HRC-X189.11_P_5e-05_MGI_20200608 189.11 Malignant neoplasm of kidney, except pelvis Binary ICD9 and ICD10 based PheWAS codes MGI Michigan Genomics Initiative Fixed threshold (5e-05) UKB GWAS (PheCode) UKB_GWAS https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761 81 0.11 4.18219e-05 0.0827 0.508 0.481-0.533 OR 1.74 0.864-3.5 1.74 0.864-3.5 1.53 0.905-2.6 1.53 0.905-2.6 1.18 0.805-1.72 1.18 0.805-1.72 1.2 0.911-1.58 1.2 0.911-1.58 1.17 0.958-1.42 1.17 0.958-1.42 1.17 0.905-1.51 0.232 1.1 0.846-1.42 0.482 1.27 0.984-1.63 0.067 False False False False Both 536 5353 GRCh37/hg19 P<=5e-05 2020-06-08 prsweb-phecode189-11-20001-1034-p-5e-06-mgi-20200608 prsweb-phecode189-11-20001-1034-p-5e-06-mgi-20200608 PRSWEB_PHECODE189.11_20001-1034_P_5e-06_MGI_20200608 P_5e-06 PRSWEB_PHECODE189.11_20001-1034_P_5e-06_MGI_20200608 189.11 Cancer code, self-reported: kidney/renal cell cancer Binary GWAS round 2: Results shared 1st August 2018. Imputed genotypes from HRC plus UK10K & 1000 Genomes reference panels as released by UK Biobank in March 2018. MGI Michigan Genomics Initiative Fixed threshold (5e-06) UKB GWAS (PHESANT) UKB_GWAS https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761 13 0.36 0.000173975 0.0827 0.491 0.466-0.518 OR 2.32 1.24-4.33 2.32 1.24-4.33 1.62 0.97-2.72 1.62 0.97-2.72 1.59 1.13-2.24 1.59 1.13-2.24 1.23 0.931-1.61 1.23 0.931-1.61 0.981 0.798-1.2 0.981 0.798-1.2 1.03 0.805-1.32 0.811 0.943 0.733-1.21 0.645 0.966 0.752-1.24 0.787 False False False False Both 536 5353 GRCh37/hg19 P<=5e-06 2020-06-08 prsweb-phecode189-11-c3-kidney-notrenalpelvis-p-5e-06-mgi-20200608 prsweb-phecode189-11-c3-kidney-notrenalpelvis-p-5e-06-mgi-20200608 PRSWEB_PHECODE189.11_C3-KIDNEY-NOTRENALPELVIS_P_5e-06_MGI_20200608 P_5e-06 PRSWEB_PHECODE189.11_C3-KIDNEY-NOTRENALPELVIS_P_5e-06_MGI_20200608 189.11 Malignant neoplasm of kidney, except renal pelvis Binary GWAS round 2: Results shared 1st August 2018. Imputed genotypes from HRC plus UK10K & 1000 Genomes reference panels as released by UK Biobank in March 2018. MGI Michigan Genomics Initiative Fixed threshold (5e-06) UKB GWAS (FINNGEN) UKB_GWAS https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761 21 0.75 8.722e-05 0.0827 0.494 0.471-0.519 OR 1.4 0.645-3.03 1.4 0.645-3.03 0.967 0.509-1.84 0.967 0.509-1.84 1.07 0.717-1.59 1.07 0.717-1.59 1.02 0.758-1.36 1.02 0.758-1.36 0.961 0.782-1.18 0.961 0.782-1.18 1.07 0.831-1.38 0.596 1.15 0.892-1.47 0.286 1.03 0.8-1.33 0.805 False False False False Both 536 5353 GRCh37/hg19 P<=5e-06 2020-06-08 prsweb-phecode189-11-c64-p-5e-06-mgi-20200608 prsweb-phecode189-11-c64-p-5e-06-mgi-20200608 PRSWEB_PHECODE189.11_C64_P_5e-06_MGI_20200608 P_5e-06 PRSWEB_PHECODE189.11_C64_P_5e-06_MGI_20200608 189.11 Diagnoses - main ICD10: C64 Malignant neoplasm of kidney, except renal pelvis Binary GWAS round 2: Results shared 1st August 2018. Imputed genotypes from HRC plus UK10K & 1000 Genomes reference panels as released by UK Biobank in March 2018. MGI Michigan Genomics Initiative Fixed threshold (5e-06) UKB GWAS (ICD10) UKB_GWAS https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761 24 0.89 0.000274342 0.0827 0.486 0.462-0.515 OR 1.56 0.75-3.25 1.56 0.75-3.25 1.34 0.765-2.33 1.34 0.765-2.33 1.06 0.713-1.58 1.06 0.713-1.58 1.01 0.754-1.36 1.01 0.754-1.36 1.08 0.879-1.32 1.08 0.879-1.32 1.17 0.912-1.5 0.215 0.993 0.766-1.29 0.955 1.12 0.87-1.44 0.378 False False False False Both 536 5353 GRCh37/hg19 P<=5e-06 2020-06-08 prsweb-phecode189-11-gwas-catalog-r2019-05-03-x189-11-p-5e-06-mgi-20200608 prsweb-phecode189-11-gwas-catalog-r2019-05-03-x189-11-p-5e-06-mgi-20200608 PRSWEB_PHECODE189.11_GWAS-Catalog-r2019-05-03-X189.11_P_5e-06_MGI_20200608 P_5e-06 PRSWEB_PHECODE189.11_GWAS-Catalog-r2019-05-03-X189.11_P_5e-06_MGI_20200608 189.11 Renal cell carcinoma;Wilms tumor Binary 15 unique SNPs MGI Michigan Genomics Initiative Fixed threshold (5e-06) GWAS Catalog (2019-05-03) 22544364;28598434 https://www.ncbi.nlm.nih.gov/pubmed/?term=22544364+28598434 13 0.17 0.000695805 0.0827 0.492 0.466-0.516 OR 1.78 0.882-3.59 1.78 0.882-3.59 1.15 0.634-2.08 1.15 0.634-2.08 1.49 1.06-2.11 1.49 1.06-2.11 1.24 0.946-1.64 1.24 0.946-1.64 1.06 0.864-1.29 1.06 0.864-1.29 1.11 0.863-1.43 0.415 1.06 0.821-1.37 0.651 1.12 0.872-1.45 0.368 False False False False Both 536 5353 GRCh37/hg19 P<=5e-06 2020-06-08 prsweb-phecode189-11-ukbb-saige-hrc-x189-11-p-5e-06-mgi-20200608 prsweb-phecode189-11-ukbb-saige-hrc-x189-11-p-5e-06-mgi-20200608 PRSWEB_PHECODE189.11_UKBB-SAIGE-HRC-X189.11_P_5e-06_MGI_20200608 P_5e-06 PRSWEB_PHECODE189.11_UKBB-SAIGE-HRC-X189.11_P_5e-06_MGI_20200608 189.11 Malignant neoplasm of kidney, except pelvis Binary ICD9 and ICD10 based PheWAS codes MGI Michigan Genomics Initiative Fixed threshold (5e-06) UKB GWAS (PheCode) UKB_GWAS https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761 13 0.23 0.000891007 0.0827 0.489 0.463-0.513 OR 1.01 0.417-2.46 1.01 0.417-2.46 1.45 0.845-2.5 1.45 0.845-2.5 1.55 1.1-2.18 1.55 1.1-2.18 1.27 0.971-1.67 1.27 0.971-1.67 1.05 0.861-1.29 1.05 0.861-1.29 0.851 0.656-1.11 0.227 1.15 0.902-1.47 0.259 1.06 0.825-1.36 0.659 False False False False Both 536 5353 GRCh37/hg19 P<=5e-06 2020-06-08 prsweb-phecode189-11-gwas-catalog-r2019-05-03-x189-11-p-5e-07-mgi-20200608 prsweb-phecode189-11-gwas-catalog-r2019-05-03-x189-11-p-5e-07-mgi-20200608 PRSWEB_PHECODE189.11_GWAS-Catalog-r2019-05-03-X189.11_P_5e-07_MGI_20200608 P_5e-07 PRSWEB_PHECODE189.11_GWAS-Catalog-r2019-05-03-X189.11_P_5e-07_MGI_20200608 189.11 Renal cell carcinoma;Wilms tumor Binary 15 unique SNPs MGI Michigan Genomics Initiative Fixed threshold (5e-07) GWAS Catalog (2019-05-03) 22544364;28598434 https://www.ncbi.nlm.nih.gov/pubmed/?term=22544364+28598434 13 0.17 0.000695805 0.0827 0.492 0.466-0.516 OR 1.78 0.882-3.59 1.78 0.882-3.59 1.15 0.634-2.08 1.15 0.634-2.08 1.49 1.06-2.11 1.49 1.06-2.11 1.24 0.946-1.64 1.24 0.946-1.64 1.06 0.864-1.29 1.06 0.864-1.29 1.11 0.863-1.43 0.415 1.06 0.821-1.37 0.651 1.12 0.872-1.45 0.368 False False False False Both 536 5353 GRCh37/hg19 P<=5e-07 2020-06-08 prsweb-phecode189-11-gwas-catalog-r2019-05-03-x189-11-p-5e-09-mgi-20200608 prsweb-phecode189-11-gwas-catalog-r2019-05-03-x189-11-p-5e-09-mgi-20200608 PRSWEB_PHECODE189.11_GWAS-Catalog-r2019-05-03-X189.11_P_5e-09_MGI_20200608 P_5e-09 PRSWEB_PHECODE189.11_GWAS-Catalog-r2019-05-03-X189.11_P_5e-09_MGI_20200608 189.11 Renal cell carcinoma;Wilms tumor Binary 15 unique SNPs MGI Michigan Genomics Initiative Fixed threshold (5e-09) GWAS Catalog (2019-05-03) 22544364;28598434 https://www.ncbi.nlm.nih.gov/pubmed/?term=22544364+28598434 8 0.2 0.000357801 0.0827 0.489 0.464-0.514 OR 1.57 0.752-3.27 1.57 0.752-3.27 1.44 0.835-2.47 1.44 0.835-2.47 1.33 0.927-1.91 1.33 0.927-1.91 1.22 0.927-1.61 1.22 0.927-1.61 1.11 0.906-1.35 1.11 0.906-1.35 0.998 0.772-1.29 0.988 0.986 0.762-1.28 0.914 1.1 0.851-1.41 0.475 False False False False Both 536 5353 GRCh37/hg19 P<=5e-09 2020-06-08 prsweb-phecode189-11-gwas-catalog-r2019-05-03-x189-11-p-5e-08-mgi-20200608 prsweb-phecode189-11-gwas-catalog-r2019-05-03-x189-11-p-5e-08-mgi-20200608 PRSWEB_PHECODE189.11_GWAS-Catalog-r2019-05-03-X189.11_P_5e-08_MGI_20200608 P_5e-08 PRSWEB_PHECODE189.11_GWAS-Catalog-r2019-05-03-X189.11_P_5e-08_MGI_20200608 189.11 Renal cell carcinoma;Wilms tumor Binary 15 unique SNPs MGI Michigan Genomics Initiative GWAS Hits GWAS Catalog (2019-05-03) 22544364;28598434 https://www.ncbi.nlm.nih.gov/pubmed/?term=22544364+28598434 12 0.15 0.000756919 0.0827 0.493 0.467-0.517 OR 1.58 0.758-3.3 1.58 0.758-3.3 1.43 0.834-2.47 1.43 0.834-2.47 1.45 1.02-2.06 1.45 1.02-2.06 1.18 0.89-1.55 1.18 0.89-1.55 1.07 0.873-1.31 1.07 0.873-1.31 1.14 0.881-1.47 0.324 1.11 0.859-1.44 0.422 1.16 0.903-1.5 0.239 False False False False Both 536 5353 GRCh37/hg19 P<=5e-08 2020-06-08 prsweb-phecode189-11-20001-1034-pt-mgi-20200608 prsweb-phecode189-11-20001-1034-pt-mgi-20200608 PRSWEB_PHECODE189.11_20001-1034_PT_MGI_20200608 P&T PRSWEB_PHECODE189.11_20001-1034_PT_MGI_20200608 189.11 Cancer code, self-reported: kidney/renal cell cancer Binary GWAS round 2: Results shared 1st August 2018. Imputed genotypes from HRC plus UK10K & 1000 Genomes reference panels as released by UK Biobank in March 2018. MGI Michigan Genomics Initiative P&T UKB GWAS (PHESANT) UKB_GWAS https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761 17 0.27 0.000290807 0.0827 0.496 0.471-0.523 OR 1.74 0.863-3.5 1.74 0.863-3.5 1.24 0.7-2.21 1.24 0.7-2.21 1.38 0.967-1.98 1.38 0.967-1.98 1.32 1.01-1.72 1.32 1.01-1.72 1.09 0.894-1.34 1.09 0.894-1.34 1.38 1.07-1.78 0.0125 1.11 0.854-1.45 0.431 1.26 0.972-1.62 0.0814 False False False False Both 536 5353 GRCh37/hg19 P<=7.94e-06 2020-06-08 prsweb-phecode189-11-c3-kidney-notrenalpelvis-pt-mgi-20200608 prsweb-phecode189-11-c3-kidney-notrenalpelvis-pt-mgi-20200608 PRSWEB_PHECODE189.11_C3-KIDNEY-NOTRENALPELVIS_PT_MGI_20200608 P&T PRSWEB_PHECODE189.11_C3-KIDNEY-NOTRENALPELVIS_PT_MGI_20200608 189.11 Malignant neoplasm of kidney, except renal pelvis Binary GWAS round 2: Results shared 1st August 2018. Imputed genotypes from HRC plus UK10K & 1000 Genomes reference panels as released by UK Biobank in March 2018. MGI Michigan Genomics Initiative P&T UKB GWAS (FINNGEN) UKB_GWAS https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761 11 0.71 0.000505883 0.0827 0.486 0.463-0.511 OR 0.46 0.128-1.65 0.46 0.128-1.65 1.26 0.707-2.23 1.26 0.707-2.23 0.981 0.652-1.48 0.981 0.652-1.48 1.08 0.808-1.44 1.08 0.808-1.44 1.03 0.837-1.26 1.03 0.837-1.26 0.99 0.769-1.27 0.94 1.03 0.802-1.32 0.817 1.04 0.808-1.33 0.771 False False False False Both 536 5353 GRCh37/hg19 P<=2.51e-06 2020-06-08 prsweb-phecode189-11-c64-pt-mgi-20200608 prsweb-phecode189-11-c64-pt-mgi-20200608 PRSWEB_PHECODE189.11_C64_PT_MGI_20200608 P&T PRSWEB_PHECODE189.11_C64_PT_MGI_20200608 189.11 Diagnoses - main ICD10: C64 Malignant neoplasm of kidney, except renal pelvis Binary GWAS round 2: Results shared 1st August 2018. Imputed genotypes from HRC plus UK10K & 1000 Genomes reference panels as released by UK Biobank in March 2018. MGI Michigan Genomics Initiative P&T UKB GWAS (ICD10) UKB_GWAS https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761 24 0.89 0.000274342 0.0827 0.486 0.462-0.515 OR 1.56 0.75-3.25 1.56 0.75-3.25 1.34 0.765-2.33 1.34 0.765-2.33 1.06 0.713-1.58 1.06 0.713-1.58 1.01 0.754-1.36 1.01 0.754-1.36 1.08 0.879-1.32 1.08 0.879-1.32 1.17 0.912-1.5 0.215 0.993 0.766-1.29 0.955 1.12 0.87-1.44 0.378 False False False False Both 536 5353 GRCh37/hg19 P<=5e-06 2020-06-08 prsweb-phecode189-11-gwas-catalog-r2019-05-03-x189-11-pt-mgi-20200608 prsweb-phecode189-11-gwas-catalog-r2019-05-03-x189-11-pt-mgi-20200608 PRSWEB_PHECODE189.11_GWAS-Catalog-r2019-05-03-X189.11_PT_MGI_20200608 P&T PRSWEB_PHECODE189.11_GWAS-Catalog-r2019-05-03-X189.11_PT_MGI_20200608 189.11 Renal cell carcinoma;Wilms tumor Binary 15 unique SNPs MGI Michigan Genomics Initiative P&T GWAS Catalog (2019-05-03) 22544364;28598434 https://www.ncbi.nlm.nih.gov/pubmed/?term=22544364+28598434 12 0.15 0.000756919 0.0827 0.493 0.467-0.517 OR 1.58 0.758-3.3 1.58 0.758-3.3 1.43 0.834-2.47 1.43 0.834-2.47 1.45 1.02-2.06 1.45 1.02-2.06 1.18 0.89-1.55 1.18 0.89-1.55 1.07 0.873-1.31 1.07 0.873-1.31 1.14 0.881-1.47 0.324 1.11 0.859-1.44 0.422 1.16 0.903-1.5 0.239 False False False False Both 536 5353 GRCh37/hg19 P<=5e-08 2020-06-08 prsweb-phecode189-11-ukbb-saige-hrc-x189-11-pt-mgi-20200608 prsweb-phecode189-11-ukbb-saige-hrc-x189-11-pt-mgi-20200608 PRSWEB_PHECODE189.11_UKBB-SAIGE-HRC-X189.11_PT_MGI_20200608 P&T PRSWEB_PHECODE189.11_UKBB-SAIGE-HRC-X189.11_PT_MGI_20200608 189.11 Malignant neoplasm of kidney, except pelvis Binary ICD9 and ICD10 based PheWAS codes MGI Michigan Genomics Initiative P&T UKB GWAS (PheCode) UKB_GWAS https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761 11 0.097 0.00127437 0.0827 0.495 0.47-0.518 OR 1.95 0.998-3.82 1.95 0.998-3.82 1.72 1.04-2.85 1.72 1.04-2.85 1.34 0.934-1.93 1.34 0.934-1.93 1.18 0.897-1.56 1.18 0.897-1.56 1.04 0.851-1.28 1.04 0.851-1.28 0.92 0.71-1.19 0.527 1.16 0.909-1.49 0.23 1.07 0.834-1.38 0.588 False False False False Both 536 5353 GRCh37/hg19 P<=3.98e-06 2020-06-08 prsweb-phecode189-11-20001-1034-prs-cs-mgi-20200608 prsweb-phecode189-11-20001-1034-prs-cs-mgi-20200608 PRSWEB_PHECODE189.11_20001-1034_PRS-CS_MGI_20200608 PRS-CS PRSWEB_PHECODE189.11_20001-1034_PRS-CS_MGI_20200608 189.11 Cancer code, self-reported: kidney/renal cell cancer Binary GWAS round 2: Results shared 1st August 2018. Imputed genotypes from HRC plus UK10K & 1000 Genomes reference panels as released by UK Biobank in March 2018. MGI Michigan Genomics Initiative PRS-CS UKB GWAS (PHESANT) UKB_GWAS https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761 1067434 0.19 0.000976903 0.0827 0.513 0.487-0.542 OR 1.58 0.757-3.28 1.58 0.757-3.28 1.53 0.903-2.59 1.53 0.903-2.59 1.42 0.996-2.02 1.42 0.996-2.02 1.4 1.08-1.82 1.4 1.08-1.82 1.18 0.972-1.44 1.18 0.972-1.44 1.04 0.809-1.33 0.765 0.875 0.674-1.13 0.313 1.14 0.894-1.46 0.29 False False False False Both 536 5353 GRCh37/hg19 auto 2020-06-08 prsweb-phecode189-11-c3-kidney-notrenalpelvis-prs-cs-mgi-20200608 prsweb-phecode189-11-c3-kidney-notrenalpelvis-prs-cs-mgi-20200608 PRSWEB_PHECODE189.11_C3-KIDNEY-NOTRENALPELVIS_PRS-CS_MGI_20200608 PRS-CS PRSWEB_PHECODE189.11_C3-KIDNEY-NOTRENALPELVIS_PRS-CS_MGI_20200608 189.11 Malignant neoplasm of kidney, except renal pelvis Binary GWAS round 2: Results shared 1st August 2018. Imputed genotypes from HRC plus UK10K & 1000 Genomes reference panels as released by UK Biobank in March 2018. MGI Michigan Genomics Initiative PRS-CS UKB GWAS (FINNGEN) UKB_GWAS https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761 1096344 0.054 1.63935e-05 0.0826 0.525 0.502-0.549 OR 1.56 0.751-3.26 1.56 0.751-3.26 1.05 0.569-1.95 1.05 0.569-1.95 0.98 0.651-1.48 0.98 0.651-1.48 0.954 0.706-1.29 0.954 0.706-1.29 1.08 0.885-1.32 1.08 0.885-1.32 1.18 0.905-1.53 0.225 1.33 1.03-1.72 0.029 1.27 0.981-1.64 0.0697 False False False False Both 536 5353 GRCh37/hg19 auto 2020-06-08 prsweb-phecode189-11-c64-prs-cs-mgi-20200608 prsweb-phecode189-11-c64-prs-cs-mgi-20200608 PRSWEB_PHECODE189.11_C64_PRS-CS_MGI_20200608 PRS-CS PRSWEB_PHECODE189.11_C64_PRS-CS_MGI_20200608 189.11 Diagnoses - main ICD10: C64 Malignant neoplasm of kidney, except renal pelvis Binary GWAS round 2: Results shared 1st August 2018. Imputed genotypes from HRC plus UK10K & 1000 Genomes reference panels as released by UK Biobank in March 2018. MGI Michigan Genomics Initiative PRS-CS UKB GWAS (ICD10) UKB_GWAS https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761 1092593 0.33 5.84998e-05 0.0827 0.514 0.489-0.538 OR 1.58 0.76-3.3 1.58 0.76-3.3 1.35 0.772-2.35 1.35 0.772-2.35 0.904 0.592-1.38 0.904 0.592-1.38 0.969 0.719-1.31 0.969 0.719-1.31 0.998 0.813-1.22 0.998 0.813-1.22 0.901 0.694-1.17 0.436 1.24 0.971-1.58 0.085 1.03 0.803-1.33 0.797 False False False False Both 536 5353 GRCh37/hg19 auto 2020-06-08 prsweb-phecode189-11-ukbb-saige-hrc-x189-11-prs-cs-mgi-20200608 prsweb-phecode189-11-ukbb-saige-hrc-x189-11-prs-cs-mgi-20200608 PRSWEB_PHECODE189.11_UKBB-SAIGE-HRC-X189.11_PRS-CS_MGI_20200608 PRS-CS PRSWEB_PHECODE189.11_UKBB-SAIGE-HRC-X189.11_PRS-CS_MGI_20200608 189.11 Malignant neoplasm of kidney, except pelvis Binary ICD9 and ICD10 based PheWAS codes MGI Michigan Genomics Initiative PRS-CS UKB GWAS (PheCode) UKB_GWAS https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761 1119238 0.22 1.08162e-05 0.0827 0.515 0.489-0.536 OR 1.18 0.518-2.69 1.18 0.518-2.69 1.53 0.902-2.59 1.53 0.902-2.59 1.34 0.933-1.93 1.34 0.933-1.93 1.14 0.86-1.51 1.14 0.86-1.51 0.951 0.773-1.17 0.951 0.773-1.17 1.01 0.777-1.31 0.94 1.38 1.08-1.77 0.00957 1.07 0.826-1.39 0.607 False False False False Both 536 5353 GRCh37/hg19 auto 2020-06-08 prsweb-phecode189-11-20001-1034-lassosum-mgi-20200608 prsweb-phecode189-11-20001-1034-lassosum-mgi-20200608 PRSWEB_PHECODE189.11_20001-1034_LASSOSUM_MGI_20200608 Lassosum PRSWEB_PHECODE189.11_20001-1034_LASSOSUM_MGI_20200608 189.11 Cancer code, self-reported: kidney/renal cell cancer Binary GWAS round 2: Results shared 1st August 2018. Imputed genotypes from HRC plus UK10K & 1000 Genomes reference panels as released by UK Biobank in March 2018. MGI Michigan Genomics Initiative lassosum UKB GWAS (PHESANT) UKB_GWAS https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761 4720259 0.16 0.00101437 0.0827 0.512 0.486-0.538 OR 1.2 0.528-2.75 1.2 0.528-2.75 1.36 0.777-2.37 1.36 0.777-2.37 1.81 1.31-2.5 1.81 1.31-2.5 1.36 1.04-1.78 1.36 1.04-1.78 1.18 0.967-1.44 1.18 0.967-1.44 1.08 0.843-1.39 0.534 0.889 0.684-1.15 0.376 1.16 0.91-1.49 0.228 False False False False Both 536 5353 GRCh37/hg19 s=1;Lambda=0.001 2020-06-08 prsweb-phecode189-11-c3-kidney-notrenalpelvis-lassosum-mgi-20200608 prsweb-phecode189-11-c3-kidney-notrenalpelvis-lassosum-mgi-20200608 PRSWEB_PHECODE189.11_C3-KIDNEY-NOTRENALPELVIS_LASSOSUM_MGI_20200608 Lassosum PRSWEB_PHECODE189.11_C3-KIDNEY-NOTRENALPELVIS_LASSOSUM_MGI_20200608 189.11 Malignant neoplasm of kidney, except renal pelvis Binary GWAS round 2: Results shared 1st August 2018. Imputed genotypes from HRC plus UK10K & 1000 Genomes reference panels as released by UK Biobank in March 2018. MGI Michigan Genomics Initiative lassosum UKB GWAS (FINNGEN) UKB_GWAS https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761 37 0.83 0.00116802 0.0827 0.503 0.482-0.53 OR 1.17 0.515-2.68 1.17 0.515-2.68 1.23 0.689-2.18 1.23 0.689-2.18 0.892 0.583-1.36 0.892 0.583-1.36 1.01 0.75-1.35 1.01 0.75-1.35 1.04 0.845-1.27 1.04 0.845-1.27 1.07 0.827-1.38 0.608 1.19 0.928-1.53 0.168 1.12 0.867-1.44 0.392 False False False False Both 536 5353 GRCh37/hg19 s=1;Lambda=0.07848 2020-06-08