prs_id slug legacy_id legacy_model prswebprefix trait_code trait_name trait_type description cohort cohort_label method gwas_source reference_label reference_url snp_count p_value pseudo_r2 brier_score mse aauc aauc_ci effect_metric top_effect_1 top_effect_1_ci top_or_1 top_or_1_ci top_effect_2 top_effect_2_ci top_or_2 top_or_2_ci top_effect_5 top_effect_5_ci top_or_5 top_or_5_ci top_effect_10 top_effect_10_ci top_or_10 top_or_10_ci top_effect_25 top_effect_25_ci top_or_25 top_or_25_ci q1_vs_q2_effect q1_vs_q2_effect_ci q1_vs_q2_p_value q1_vs_q3_effect q1_vs_q3_effect_ci q1_vs_q3_p_value q1_vs_q4_effect q1_vs_q4_effect_ci q1_vs_q4_p_value nominally_significant reversed_effect_warning underpowered_warning upload_to_portal sex cases controls genome_build tuning_parameter weights_external_url weights_url phewas_download_url exclusion_download_url last_updated prsweb-phecode189-2-20001-1035-p-5e-05-mgi-20200608 prsweb-phecode189-2-20001-1035-p-5e-05-mgi-20200608 PRSWEB_PHECODE189.2_20001-1035_P_5e-05_MGI_20200608 P_5e-05 PRSWEB_PHECODE189.2_20001-1035_P_5e-05_MGI_20200608 189.2 Cancer code, self-reported: bladder cancer Binary GWAS round 2: Results shared 1st August 2018. Imputed genotypes from HRC plus UK10K & 1000 Genomes reference panels as released by UK Biobank in March 2018. MGI Michigan Genomics Initiative Fixed threshold (5e-05) UKB GWAS (PHESANT) UKB_GWAS https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761 131 0.28 0.00197139 0.0923 0.51 0.491-0.529 OR 0.799 0.354-1.8 0.799 0.354-1.8 0.886 0.512-1.53 0.886 0.512-1.53 1.02 0.729-1.43 1.02 0.729-1.43 1.11 0.872-1.4 1.11 0.872-1.4 1.06 0.9-1.26 1.06 0.9-1.26 1.22 0.989-1.51 0.0632 1.1 0.885-1.36 0.396 1.17 0.95-1.45 0.137 False False False False Both 789 6833 GRCh37/hg19 P<=5e-05 2020-06-08 prsweb-phecode189-2-c3-bladder-p-5e-05-mgi-20200608 prsweb-phecode189-2-c3-bladder-p-5e-05-mgi-20200608 PRSWEB_PHECODE189.2_C3-BLADDER_P_5e-05_MGI_20200608 P_5e-05 PRSWEB_PHECODE189.2_C3-BLADDER_P_5e-05_MGI_20200608 189.2 Malignant neoplasm of bladder Binary GWAS round 2: Results shared 1st August 2018. Imputed genotypes from HRC plus UK10K & 1000 Genomes reference panels as released by UK Biobank in March 2018. MGI Michigan Genomics Initiative Fixed threshold (5e-05) UKB GWAS (FINNGEN) UKB_GWAS https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761 125 0.51 8.38031e-06 0.0923 0.502 0.481-0.523 OR 1.01 0.489-2.07 1.01 0.489-2.07 1 0.598-1.69 1 0.598-1.69 1.01 0.723-1.41 1.01 0.723-1.41 0.938 0.729-1.21 0.938 0.729-1.21 1.03 0.873-1.22 1.03 0.873-1.22 0.993 0.805-1.22 0.945 1.02 0.829-1.26 0.845 1.04 0.846-1.28 0.703 False False False False Both 789 6833 GRCh37/hg19 P<=5e-05 2020-06-08 prsweb-phecode189-2-c67-p-5e-05-mgi-20200608 prsweb-phecode189-2-c67-p-5e-05-mgi-20200608 PRSWEB_PHECODE189.2_C67_P_5e-05_MGI_20200608 P_5e-05 PRSWEB_PHECODE189.2_C67_P_5e-05_MGI_20200608 189.2 Diagnoses - main ICD10: C67 Malignant neoplasm of bladder Binary GWAS round 2: Results shared 1st August 2018. Imputed genotypes from HRC plus UK10K & 1000 Genomes reference panels as released by UK Biobank in March 2018. MGI Michigan Genomics Initiative Fixed threshold (5e-05) UKB GWAS (ICD10) UKB_GWAS https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761 147 0.24 3.00924e-05 0.0922 0.504 0.483-0.525 OR 1.03 0.499-2.11 1.03 0.499-2.11 1.01 0.6-1.69 1.01 0.6-1.69 1.17 0.85-1.6 1.17 0.85-1.6 1.21 0.961-1.52 1.21 0.961-1.52 0.996 0.84-1.18 0.996 0.84-1.18 0.92 0.743-1.14 0.443 1.1 0.899-1.35 0.349 1 0.814-1.24 0.982 False False False False Both 789 6833 GRCh37/hg19 P<=5e-05 2020-06-08 prsweb-phecode189-2-gwas-catalog-r2019-05-03-x189-2-p-5e-05-mgi-20200608 prsweb-phecode189-2-gwas-catalog-r2019-05-03-x189-2-p-5e-05-mgi-20200608 PRSWEB_PHECODE189.2_GWAS-Catalog-r2019-05-03-X189.2_P_5e-05_MGI_20200608 P_5e-05 PRSWEB_PHECODE189.2_GWAS-Catalog-r2019-05-03-X189.2_P_5e-05_MGI_20200608 189.2 Bladder cancer;Urinary bladder cancer Binary 18 unique SNPs MGI Michigan Genomics Initiative Fixed threshold (5e-05) GWAS Catalog (2019-05-03) 18794855;19648920;20348956;20972438;21750109;24163127;24861552 https://www.ncbi.nlm.nih.gov/pubmed/?term=18794855+19648920+20348956+20972438+21750109+24163127+24861552 15 1.9e-11 0.00344644 0.0917 0.572 0.55-0.594 OR 2.12 1.22-3.66 2.12 1.22-3.66 1.8 1.19-2.72 1.8 1.19-2.72 1.68 1.27-2.21 1.68 1.27-2.21 1.63 1.32-2.01 1.63 1.32-2.01 1.63 1.39-1.9 1.63 1.39-1.9 1.24 0.983-1.57 0.0694 1.43 1.14-1.79 0.00201 1.99 1.61-2.47 2.85e-10 True False False False Both 789 6833 GRCh37/hg19 P<=5e-05 2020-06-08 prsweb-phecode189-2-ukbb-saige-hrc-x189-2-p-5e-05-mgi-20200608 prsweb-phecode189-2-ukbb-saige-hrc-x189-2-p-5e-05-mgi-20200608 PRSWEB_PHECODE189.2_UKBB-SAIGE-HRC-X189.2_P_5e-05_MGI_20200608 P_5e-05 PRSWEB_PHECODE189.2_UKBB-SAIGE-HRC-X189.2_P_5e-05_MGI_20200608 189.2 Cancer of bladder Binary ICD9 and ICD10 based PheWAS codes MGI Michigan Genomics Initiative Fixed threshold (5e-05) UKB GWAS (PheCode) UKB_GWAS https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761 130 0.019 0.00192876 0.0922 0.519 0.499-0.541 OR 1.59 0.876-2.87 1.59 0.876-2.87 1.49 0.96-2.31 1.49 0.96-2.31 1.2 0.878-1.64 1.2 0.878-1.64 1.2 0.955-1.51 1.2 0.955-1.51 1.16 0.981-1.37 1.16 0.981-1.37 1.09 0.88-1.34 0.444 0.978 0.789-1.21 0.843 1.17 0.95-1.44 0.139 True False False False Both 789 6833 GRCh37/hg19 P<=5e-05 2020-06-08 prsweb-phecode189-2-20001-1035-p-5e-06-mgi-20200608 prsweb-phecode189-2-20001-1035-p-5e-06-mgi-20200608 PRSWEB_PHECODE189.2_20001-1035_P_5e-06_MGI_20200608 P_5e-06 PRSWEB_PHECODE189.2_20001-1035_P_5e-06_MGI_20200608 189.2 Cancer code, self-reported: bladder cancer Binary GWAS round 2: Results shared 1st August 2018. Imputed genotypes from HRC plus UK10K & 1000 Genomes reference panels as released by UK Biobank in March 2018. MGI Michigan Genomics Initiative Fixed threshold (5e-06) UKB GWAS (PHESANT) UKB_GWAS https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761 17 0.024 2.94001e-06 0.0922 0.505 0.484-0.525 OR 1.41 0.75-2.66 1.41 0.75-2.66 1.32 0.822-2.12 1.32 0.822-2.12 0.935 0.661-1.32 0.935 0.661-1.32 1.16 0.916-1.46 1.16 0.916-1.46 1.14 0.969-1.35 1.14 0.969-1.35 1.24 0.997-1.54 0.0527 1.31 1.05-1.62 0.0154 1.35 1.09-1.68 0.0054 True False False False Both 789 6833 GRCh37/hg19 P<=5e-06 2020-06-08 prsweb-phecode189-2-c67-p-5e-06-mgi-20200608 prsweb-phecode189-2-c67-p-5e-06-mgi-20200608 PRSWEB_PHECODE189.2_C67_P_5e-06_MGI_20200608 P_5e-06 PRSWEB_PHECODE189.2_C67_P_5e-06_MGI_20200608 189.2 Diagnoses - main ICD10: C67 Malignant neoplasm of bladder Binary GWAS round 2: Results shared 1st August 2018. Imputed genotypes from HRC plus UK10K & 1000 Genomes reference panels as released by UK Biobank in March 2018. MGI Michigan Genomics Initiative Fixed threshold (5e-06) UKB GWAS (ICD10) UKB_GWAS https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761 28 0.68 0.000431496 0.0923 0.497 0.476-0.517 OR 0.43 0.146-1.27 0.43 0.146-1.27 0.595 0.306-1.16 0.595 0.306-1.16 0.911 0.642-1.29 0.911 0.642-1.29 0.968 0.754-1.24 0.968 0.754-1.24 1.01 0.85-1.19 1.01 0.85-1.19 1.08 0.875-1.34 0.469 1.14 0.926-1.41 0.216 1.07 0.866-1.32 0.527 False False False False Both 789 6833 GRCh37/hg19 P<=5e-06 2020-06-08 prsweb-phecode189-2-gwas-catalog-r2019-05-03-x189-2-p-5e-06-mgi-20200608 prsweb-phecode189-2-gwas-catalog-r2019-05-03-x189-2-p-5e-06-mgi-20200608 PRSWEB_PHECODE189.2_GWAS-Catalog-r2019-05-03-X189.2_P_5e-06_MGI_20200608 P_5e-06 PRSWEB_PHECODE189.2_GWAS-Catalog-r2019-05-03-X189.2_P_5e-06_MGI_20200608 189.2 Bladder cancer;Urinary bladder cancer Binary 18 unique SNPs MGI Michigan Genomics Initiative Fixed threshold (5e-06) GWAS Catalog (2019-05-03) 18794855;19648920;20348956;20972438;21750109;24163127;24861552 https://www.ncbi.nlm.nih.gov/pubmed/?term=18794855+19648920+20348956+20972438+21750109+24163127+24861552 15 1.9e-11 0.00344644 0.0917 0.572 0.55-0.594 OR 2.12 1.22-3.66 2.12 1.22-3.66 1.8 1.19-2.72 1.8 1.19-2.72 1.68 1.27-2.21 1.68 1.27-2.21 1.63 1.32-2.01 1.63 1.32-2.01 1.63 1.39-1.9 1.63 1.39-1.9 1.24 0.983-1.57 0.0694 1.43 1.14-1.79 0.00201 1.99 1.61-2.47 2.85e-10 True False False False Both 789 6833 GRCh37/hg19 P<=5e-06 2020-06-08 prsweb-phecode189-2-ukbb-saige-hrc-x189-2-p-5e-06-mgi-20200608 prsweb-phecode189-2-ukbb-saige-hrc-x189-2-p-5e-06-mgi-20200608 PRSWEB_PHECODE189.2_UKBB-SAIGE-HRC-X189.2_P_5e-06_MGI_20200608 P_5e-06 PRSWEB_PHECODE189.2_UKBB-SAIGE-HRC-X189.2_P_5e-06_MGI_20200608 189.2 Cancer of bladder Binary ICD9 and ICD10 based PheWAS codes MGI Michigan Genomics Initiative Fixed threshold (5e-06) UKB GWAS (PheCode) UKB_GWAS https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761 21 0.00011 0.000818731 0.0921 0.537 0.515-0.558 OR 1.08 0.526-2.23 1.08 0.526-2.23 1.16 0.708-1.9 1.16 0.708-1.9 1.41 1.05-1.9 1.41 1.05-1.9 1.36 1.09-1.7 1.36 1.09-1.7 1.29 1.1-1.52 1.29 1.1-1.52 1.27 1.02-1.59 0.0345 1.28 1.03-1.6 0.0264 1.56 1.26-1.93 4.6e-05 True False False False Both 789 6833 GRCh37/hg19 P<=5e-06 2020-06-08 prsweb-phecode189-2-c67-p-5e-07-mgi-20200608 prsweb-phecode189-2-c67-p-5e-07-mgi-20200608 PRSWEB_PHECODE189.2_C67_P_5e-07_MGI_20200608 P_5e-07 PRSWEB_PHECODE189.2_C67_P_5e-07_MGI_20200608 189.2 Diagnoses - main ICD10: C67 Malignant neoplasm of bladder Binary GWAS round 2: Results shared 1st August 2018. Imputed genotypes from HRC plus UK10K & 1000 Genomes reference panels as released by UK Biobank in March 2018. MGI Michigan Genomics Initiative Fixed threshold (5e-07) UKB GWAS (ICD10) UKB_GWAS https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761 7 0.02 3.66687e-05 0.0922 0.512 0.492-0.53 OR 0.578 0.221-1.51 0.578 0.221-1.51 0.929 0.536-1.61 0.929 0.536-1.61 0.987 0.701-1.39 0.987 0.701-1.39 1.17 0.931-1.48 1.17 0.931-1.48 1.14 0.969-1.35 1.14 0.969-1.35 1.1 0.886-1.38 0.378 1.32 1.07-1.63 0.00984 1.3 1.05-1.61 0.0155 True False False False Both 789 6833 GRCh37/hg19 P<=5e-07 2020-06-08 prsweb-phecode189-2-gwas-catalog-r2019-05-03-x189-2-p-5e-07-mgi-20200608 prsweb-phecode189-2-gwas-catalog-r2019-05-03-x189-2-p-5e-07-mgi-20200608 PRSWEB_PHECODE189.2_GWAS-Catalog-r2019-05-03-X189.2_P_5e-07_MGI_20200608 P_5e-07 PRSWEB_PHECODE189.2_GWAS-Catalog-r2019-05-03-X189.2_P_5e-07_MGI_20200608 189.2 Bladder cancer;Urinary bladder cancer Binary 18 unique SNPs MGI Michigan Genomics Initiative Fixed threshold (5e-07) GWAS Catalog (2019-05-03) 18794855;19648920;20348956;20972438;21750109;24163127;24861552 https://www.ncbi.nlm.nih.gov/pubmed/?term=18794855+19648920+20348956+20972438+21750109+24163127+24861552 14 1.6e-11 0.00314591 0.0917 0.571 0.55-0.594 OR 1.32 0.684-2.56 1.32 0.684-2.56 2.1 1.43-3.1 2.1 1.43-3.1 1.69 1.28-2.22 1.69 1.28-2.22 1.72 1.4-2.11 1.72 1.4-2.11 1.63 1.39-1.9 1.63 1.39-1.9 1.28 1.02-1.62 0.0338 1.39 1.1-1.74 0.005 1.99 1.6-2.46 3.22e-10 True False False False Both 789 6833 GRCh37/hg19 P<=5e-07 2020-06-08 prsweb-phecode189-2-ukbb-saige-hrc-x189-2-p-5e-07-mgi-20200608 prsweb-phecode189-2-ukbb-saige-hrc-x189-2-p-5e-07-mgi-20200608 PRSWEB_PHECODE189.2_UKBB-SAIGE-HRC-X189.2_P_5e-07_MGI_20200608 P_5e-07 PRSWEB_PHECODE189.2_UKBB-SAIGE-HRC-X189.2_P_5e-07_MGI_20200608 189.2 Cancer of bladder Binary ICD9 and ICD10 based PheWAS codes MGI Michigan Genomics Initiative Fixed threshold (5e-07) UKB GWAS (PheCode) UKB_GWAS https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761 8 5.1e-07 0.00107835 0.0919 0.548 0.526-0.569 OR 1.68 0.929-3.04 1.68 0.929-3.04 1.26 0.787-2.02 1.26 0.787-2.02 1.41 1.05-1.89 1.41 1.05-1.89 1.34 1.07-1.67 1.34 1.07-1.67 1.38 1.17-1.62 1.38 1.17-1.62 1.32 1.05-1.65 0.017 1.38 1.11-1.73 0.00441 1.69 1.37-2.1 1.49e-06 True False False False Both 789 6833 GRCh37/hg19 P<=5e-07 2020-06-08 prsweb-phecode189-2-gwas-catalog-r2019-05-03-x189-2-p-5e-09-mgi-20200608 prsweb-phecode189-2-gwas-catalog-r2019-05-03-x189-2-p-5e-09-mgi-20200608 PRSWEB_PHECODE189.2_GWAS-Catalog-r2019-05-03-X189.2_P_5e-09_MGI_20200608 P_5e-09 PRSWEB_PHECODE189.2_GWAS-Catalog-r2019-05-03-X189.2_P_5e-09_MGI_20200608 189.2 Bladder cancer;Urinary bladder cancer Binary 18 unique SNPs MGI Michigan Genomics Initiative Fixed threshold (5e-09) GWAS Catalog (2019-05-03) 18794855;19648920;20348956;20972438;21750109;24163127;24861552 https://www.ncbi.nlm.nih.gov/pubmed/?term=18794855+19648920+20348956+20972438+21750109+24163127+24861552 12 2.5e-12 0.00330397 0.0916 0.574 0.552-0.596 OR 1.95 1.11-3.42 1.95 1.11-3.42 2.18 1.49-3.2 2.18 1.49-3.2 1.78 1.36-2.34 1.78 1.36-2.34 1.58 1.28-1.95 1.58 1.28-1.95 1.53 1.31-1.79 1.53 1.31-1.79 1.24 0.982-1.57 0.0711 1.55 1.24-1.94 0.000139 1.93 1.56-2.4 2.31e-09 True False False False Both 789 6833 GRCh37/hg19 P<=5e-09 2020-06-08 prsweb-phecode189-2-gwas-catalog-r2019-05-03-x189-2-p-5e-08-mgi-20200608 prsweb-phecode189-2-gwas-catalog-r2019-05-03-x189-2-p-5e-08-mgi-20200608 PRSWEB_PHECODE189.2_GWAS-Catalog-r2019-05-03-X189.2_P_5e-08_MGI_20200608 P_5e-08 PRSWEB_PHECODE189.2_GWAS-Catalog-r2019-05-03-X189.2_P_5e-08_MGI_20200608 189.2 Bladder cancer;Urinary bladder cancer Binary 18 unique SNPs MGI Michigan Genomics Initiative GWAS Hits GWAS Catalog (2019-05-03) 18794855;19648920;20348956;20972438;21750109;24163127;24861552 https://www.ncbi.nlm.nih.gov/pubmed/?term=18794855+19648920+20348956+20972438+21750109+24163127+24861552 13 8.1e-12 0.00358481 0.0917 0.572 0.55-0.594 OR 1.47 0.779-2.77 1.47 0.779-2.77 1.99 1.34-2.96 1.99 1.34-2.96 1.75 1.33-2.3 1.75 1.33-2.3 1.52 1.23-1.88 1.52 1.23-1.88 1.66 1.42-1.94 1.66 1.42-1.94 1.13 0.898-1.43 0.292 1.36 1.08-1.7 0.00764 1.94 1.57-2.39 8.27e-10 True False False True Both 789 6833 GRCh37/hg19 P<=5e-08 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000610/ScoringFiles/ https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000610/ScoringFiles/ /larsf/prsweb-data/cancerprsweb/releases/cancerprsweb_20200608/phewas/PRSWEB_PHECODE189.2_GWAS-Catalog-r2019-05-03-X189.2_P_5e-08_MGI_20200608/all.tsv /larsf/prsweb-data/cancerprsweb/releases/cancerprsweb_20200608/phewas/PRSWEB_PHECODE189.2_GWAS-Catalog-r2019-05-03-X189.2_P_5e-08_MGI_20200608/exclusion.tsv 2020-06-08 prsweb-phecode189-2-20001-1035-pt-mgi-20200608 prsweb-phecode189-2-20001-1035-pt-mgi-20200608 PRSWEB_PHECODE189.2_20001-1035_PT_MGI_20200608 P&T PRSWEB_PHECODE189.2_20001-1035_PT_MGI_20200608 189.2 Cancer code, self-reported: bladder cancer Binary GWAS round 2: Results shared 1st August 2018. Imputed genotypes from HRC plus UK10K & 1000 Genomes reference panels as released by UK Biobank in March 2018. MGI Michigan Genomics Initiative P&T UKB GWAS (PHESANT) UKB_GWAS https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761 155 0.44 0.00212147 0.0923 0.507 0.488-0.527 OR 0.549 0.21-1.44 0.549 0.21-1.44 0.896 0.518-1.55 0.896 0.518-1.55 0.823 0.572-1.18 0.823 0.572-1.18 0.946 0.736-1.21 0.946 0.736-1.21 1.04 0.878-1.23 1.04 0.878-1.23 1.33 1.07-1.64 0.00884 1.15 0.924-1.42 0.215 1.19 0.963-1.48 0.106 False False False False Both 789 6833 GRCh37/hg19 P<=6.31e-05 2020-06-08 prsweb-phecode189-2-c3-bladder-pt-mgi-20200608 prsweb-phecode189-2-c3-bladder-pt-mgi-20200608 PRSWEB_PHECODE189.2_C3-BLADDER_PT_MGI_20200608 P&T PRSWEB_PHECODE189.2_C3-BLADDER_PT_MGI_20200608 189.2 Malignant neoplasm of bladder Binary GWAS round 2: Results shared 1st August 2018. Imputed genotypes from HRC plus UK10K & 1000 Genomes reference panels as released by UK Biobank in March 2018. MGI Michigan Genomics Initiative P&T UKB GWAS (FINNGEN) UKB_GWAS https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761 5 0.51 0.00065475 0.0923 0.468 0.449-0.487 OR 0.767 0.34-1.73 0.767 0.34-1.73 0.82 0.465-1.44 0.82 0.465-1.44 0.863 0.603-1.24 0.863 0.603-1.24 1.02 0.802-1.3 1.02 0.802-1.3 1.12 0.951-1.33 1.12 0.951-1.33 0.929 0.742-1.16 0.524 1 0.803-1.25 0.984 1.11 0.895-1.38 0.337 False False False False Both 789 6833 GRCh37/hg19 P<=7.94e-07 2020-06-08 prsweb-phecode189-2-c67-pt-mgi-20200608 prsweb-phecode189-2-c67-pt-mgi-20200608 PRSWEB_PHECODE189.2_C67_PT_MGI_20200608 P&T PRSWEB_PHECODE189.2_C67_PT_MGI_20200608 189.2 Diagnoses - main ICD10: C67 Malignant neoplasm of bladder Binary GWAS round 2: Results shared 1st August 2018. Imputed genotypes from HRC plus UK10K & 1000 Genomes reference panels as released by UK Biobank in March 2018. MGI Michigan Genomics Initiative P&T UKB GWAS (ICD10) UKB_GWAS https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761 10 0.12 0.000600238 0.0922 0.504 0.483-0.524 OR 1.1 0.534-2.26 1.1 0.534-2.26 0.672 0.357-1.27 0.672 0.357-1.27 0.945 0.668-1.34 0.945 0.668-1.34 1.1 0.868-1.4 1.1 0.868-1.4 1.07 0.903-1.26 1.07 0.903-1.26 0.946 0.763-1.17 0.618 1.16 0.942-1.43 0.162 1.11 0.897-1.36 0.346 False False False False Both 789 6833 GRCh37/hg19 P<=1.58e-06 2020-06-08 prsweb-phecode189-2-gwas-catalog-r2019-05-03-x189-2-pt-mgi-20200608 prsweb-phecode189-2-gwas-catalog-r2019-05-03-x189-2-pt-mgi-20200608 PRSWEB_PHECODE189.2_GWAS-Catalog-r2019-05-03-X189.2_PT_MGI_20200608 P&T PRSWEB_PHECODE189.2_GWAS-Catalog-r2019-05-03-X189.2_PT_MGI_20200608 189.2 Bladder cancer;Urinary bladder cancer Binary 18 unique SNPs MGI Michigan Genomics Initiative P&T GWAS Catalog (2019-05-03) 18794855;19648920;20348956;20972438;21750109;24163127;24861552 https://www.ncbi.nlm.nih.gov/pubmed/?term=18794855+19648920+20348956+20972438+21750109+24163127+24861552 13 8.1e-12 0.00358481 0.0917 0.572 0.55-0.594 OR 1.47 0.779-2.77 1.47 0.779-2.77 1.99 1.34-2.96 1.99 1.34-2.96 1.75 1.33-2.3 1.75 1.33-2.3 1.52 1.23-1.88 1.52 1.23-1.88 1.66 1.42-1.94 1.66 1.42-1.94 1.13 0.898-1.43 0.292 1.36 1.08-1.7 0.00764 1.94 1.57-2.39 8.27e-10 True False False True Both 789 6833 GRCh37/hg19 P<=5e-08 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000612/ScoringFiles/ https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000612/ScoringFiles/ /larsf/prsweb-data/cancerprsweb/releases/cancerprsweb_20200608/phewas/PRSWEB_PHECODE189.2_GWAS-Catalog-r2019-05-03-X189.2_PT_MGI_20200608/all.tsv /larsf/prsweb-data/cancerprsweb/releases/cancerprsweb_20200608/phewas/PRSWEB_PHECODE189.2_GWAS-Catalog-r2019-05-03-X189.2_PT_MGI_20200608/exclusion.tsv 2020-06-08 prsweb-phecode189-2-ukbb-saige-hrc-x189-2-pt-mgi-20200608 prsweb-phecode189-2-ukbb-saige-hrc-x189-2-pt-mgi-20200608 PRSWEB_PHECODE189.2_UKBB-SAIGE-HRC-X189.2_PT_MGI_20200608 P&T PRSWEB_PHECODE189.2_UKBB-SAIGE-HRC-X189.2_PT_MGI_20200608 189.2 Cancer of bladder Binary ICD9 and ICD10 based PheWAS codes MGI Michigan Genomics Initiative P&T UKB GWAS (PheCode) UKB_GWAS https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761 106 0.032 0.00245224 0.0922 0.519 0.498-0.541 OR 0.788 0.35-1.78 0.788 0.35-1.78 1.18 0.73-1.92 1.18 0.73-1.92 1.27 0.935-1.73 1.27 0.935-1.73 1.12 0.889-1.42 1.12 0.889-1.42 1.13 0.957-1.33 1.13 0.957-1.33 1.13 0.913-1.4 0.263 1.14 0.921-1.41 0.227 1.22 0.99-1.51 0.0625 True False False True Both 789 6833 GRCh37/hg19 P<=3.98e-05 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000615/ScoringFiles/ https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000615/ScoringFiles/ /larsf/prsweb-data/cancerprsweb/releases/cancerprsweb_20200608/phewas/PRSWEB_PHECODE189.2_UKBB-SAIGE-HRC-X189.2_PT_MGI_20200608/all.tsv /larsf/prsweb-data/cancerprsweb/releases/cancerprsweb_20200608/phewas/PRSWEB_PHECODE189.2_UKBB-SAIGE-HRC-X189.2_PT_MGI_20200608/exclusion.tsv 2020-06-08 prsweb-phecode189-2-20001-1035-prs-cs-mgi-20200608 prsweb-phecode189-2-20001-1035-prs-cs-mgi-20200608 PRSWEB_PHECODE189.2_20001-1035_PRS-CS_MGI_20200608 PRS-CS PRSWEB_PHECODE189.2_20001-1035_PRS-CS_MGI_20200608 189.2 Cancer code, self-reported: bladder cancer Binary GWAS round 2: Results shared 1st August 2018. Imputed genotypes from HRC plus UK10K & 1000 Genomes reference panels as released by UK Biobank in March 2018. MGI Michigan Genomics Initiative PRS-CS UKB GWAS (PHESANT) UKB_GWAS https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761 1095241 0.015 0.000762339 0.0922 0.531 0.509-0.551 OR 0.671 0.279-1.61 0.671 0.279-1.61 0.889 0.513-1.54 0.889 0.513-1.54 1.12 0.81-1.55 1.12 0.81-1.55 1.22 0.966-1.53 1.22 0.966-1.53 1.16 0.985-1.37 1.16 0.985-1.37 0.995 0.799-1.24 0.966 1.25 1.02-1.54 0.035 1.26 1.02-1.55 0.0317 True False False True Both 789 6833 GRCh37/hg19 auto https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000607/ScoringFiles/ https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000607/ScoringFiles/ /larsf/prsweb-data/cancerprsweb/releases/cancerprsweb_20200608/phewas/PRSWEB_PHECODE189.2_20001-1035_PRS-CS_MGI_20200608/all.tsv /larsf/prsweb-data/cancerprsweb/releases/cancerprsweb_20200608/phewas/PRSWEB_PHECODE189.2_20001-1035_PRS-CS_MGI_20200608/exclusion.tsv 2020-06-08 prsweb-phecode189-2-c3-bladder-prs-cs-mgi-20200608 prsweb-phecode189-2-c3-bladder-prs-cs-mgi-20200608 PRSWEB_PHECODE189.2_C3-BLADDER_PRS-CS_MGI_20200608 PRS-CS PRSWEB_PHECODE189.2_C3-BLADDER_PRS-CS_MGI_20200608 189.2 Malignant neoplasm of bladder Binary GWAS round 2: Results shared 1st August 2018. Imputed genotypes from HRC plus UK10K & 1000 Genomes reference panels as released by UK Biobank in March 2018. MGI Michigan Genomics Initiative PRS-CS UKB GWAS (FINNGEN) UKB_GWAS https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761 1097063 0.033 8.08514e-05 0.0922 0.521 0.499-0.541 OR 1.53 0.832-2.83 1.53 0.832-2.83 1.37 0.86-2.17 1.37 0.86-2.17 1.33 0.986-1.8 1.33 0.986-1.8 1.26 1-1.58 1.26 1-1.58 1.13 0.957-1.33 1.13 0.957-1.33 1.14 0.918-1.41 0.241 1.11 0.892-1.37 0.359 1.22 0.988-1.5 0.0641 True False False True Both 789 6833 GRCh37/hg19 auto https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000608/ScoringFiles/ https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000608/ScoringFiles/ /larsf/prsweb-data/cancerprsweb/releases/cancerprsweb_20200608/phewas/PRSWEB_PHECODE189.2_C3-BLADDER_PRS-CS_MGI_20200608/all.tsv /larsf/prsweb-data/cancerprsweb/releases/cancerprsweb_20200608/phewas/PRSWEB_PHECODE189.2_C3-BLADDER_PRS-CS_MGI_20200608/exclusion.tsv 2020-06-08 prsweb-phecode189-2-c67-prs-cs-mgi-20200608 prsweb-phecode189-2-c67-prs-cs-mgi-20200608 PRSWEB_PHECODE189.2_C67_PRS-CS_MGI_20200608 PRS-CS PRSWEB_PHECODE189.2_C67_PRS-CS_MGI_20200608 189.2 Diagnoses - main ICD10: C67 Malignant neoplasm of bladder Binary GWAS round 2: Results shared 1st August 2018. Imputed genotypes from HRC plus UK10K & 1000 Genomes reference panels as released by UK Biobank in March 2018. MGI Michigan Genomics Initiative PRS-CS UKB GWAS (ICD10) UKB_GWAS https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761 1109663 0.081 0.00181871 0.0922 0.517 0.495-0.539 OR 1.52 0.806-2.87 1.52 0.806-2.87 1.35 0.841-2.16 1.35 0.841-2.16 1.06 0.758-1.47 1.06 0.758-1.47 1.3 1.04-1.62 1.3 1.04-1.62 1.1 0.929-1.3 1.1 0.929-1.3 1.05 0.854-1.3 0.624 1.02 0.828-1.27 0.827 1.13 0.916-1.39 0.258 False False False False Both 789 6833 GRCh37/hg19 auto 2020-06-08 prsweb-phecode189-2-ukbb-saige-hrc-x189-2-prs-cs-mgi-20200608 prsweb-phecode189-2-ukbb-saige-hrc-x189-2-prs-cs-mgi-20200608 PRSWEB_PHECODE189.2_UKBB-SAIGE-HRC-X189.2_PRS-CS_MGI_20200608 PRS-CS PRSWEB_PHECODE189.2_UKBB-SAIGE-HRC-X189.2_PRS-CS_MGI_20200608 189.2 Cancer of bladder Binary ICD9 and ICD10 based PheWAS codes MGI Michigan Genomics Initiative PRS-CS UKB GWAS (PheCode) UKB_GWAS https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761 1119238 0.027 0.00161079 0.0922 0.525 0.503-0.547 OR 0.675 0.28-1.62 0.675 0.28-1.62 0.862 0.489-1.52 0.862 0.489-1.52 1.03 0.736-1.44 1.03 0.736-1.44 1.31 1.04-1.64 1.31 1.04-1.64 1.15 0.978-1.36 1.15 0.978-1.36 1.12 0.9-1.39 0.312 1.18 0.955-1.46 0.124 1.27 1.03-1.56 0.0278 True False False True Both 789 6833 GRCh37/hg19 auto https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000614/ScoringFiles/ https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000614/ScoringFiles/ /larsf/prsweb-data/cancerprsweb/releases/cancerprsweb_20200608/phewas/PRSWEB_PHECODE189.2_UKBB-SAIGE-HRC-X189.2_PRS-CS_MGI_20200608/all.tsv /larsf/prsweb-data/cancerprsweb/releases/cancerprsweb_20200608/phewas/PRSWEB_PHECODE189.2_UKBB-SAIGE-HRC-X189.2_PRS-CS_MGI_20200608/exclusion.tsv 2020-06-08 prsweb-phecode189-2-20001-1035-lassosum-mgi-20200608 prsweb-phecode189-2-20001-1035-lassosum-mgi-20200608 PRSWEB_PHECODE189.2_20001-1035_LASSOSUM_MGI_20200608 Lassosum PRSWEB_PHECODE189.2_20001-1035_LASSOSUM_MGI_20200608 189.2 Cancer code, self-reported: bladder cancer Binary GWAS round 2: Results shared 1st August 2018. Imputed genotypes from HRC plus UK10K & 1000 Genomes reference panels as released by UK Biobank in March 2018. MGI Michigan Genomics Initiative lassosum UKB GWAS (PHESANT) UKB_GWAS https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761 29094 0.12 0.00201186 0.0922 0.516 0.497-0.536 OR 0.943 0.439-2.02 0.943 0.439-2.02 1.12 0.673-1.85 1.12 0.673-1.85 1.26 0.926-1.72 1.26 0.926-1.72 1.01 0.792-1.29 1.01 0.792-1.29 0.974 0.821-1.16 0.974 0.821-1.16 1.19 0.962-1.47 0.109 1.24 1.01-1.53 0.0442 1.11 0.892-1.37 0.355 False False False False Both 789 6833 GRCh37/hg19 s=1;Lambda=0.04833 2020-06-08 prsweb-phecode189-2-c67-lassosum-mgi-20200608 prsweb-phecode189-2-c67-lassosum-mgi-20200608 PRSWEB_PHECODE189.2_C67_LASSOSUM_MGI_20200608 Lassosum PRSWEB_PHECODE189.2_C67_LASSOSUM_MGI_20200608 189.2 Diagnoses - main ICD10: C67 Malignant neoplasm of bladder Binary GWAS round 2: Results shared 1st August 2018. Imputed genotypes from HRC plus UK10K & 1000 Genomes reference panels as released by UK Biobank in March 2018. MGI Michigan Genomics Initiative lassosum UKB GWAS (ICD10) UKB_GWAS https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761 1130 0.0074 0.00275366 0.0922 0.528 0.508-0.549 OR 1.69 0.934-3.06 1.69 0.934-3.06 1.22 0.754-1.98 1.22 0.754-1.98 1.23 0.906-1.68 1.23 0.906-1.68 1.18 0.937-1.49 1.18 0.937-1.49 1.08 0.916-1.28 1.08 0.916-1.28 1.23 0.986-1.52 0.0662 1.33 1.07-1.65 0.0091 1.28 1.03-1.58 0.026 True False False True Both 789 6833 GRCh37/hg19 s=1;Lambda=0.04833 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000609/ScoringFiles/ https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000609/ScoringFiles/ /larsf/prsweb-data/cancerprsweb/releases/cancerprsweb_20200608/phewas/PRSWEB_PHECODE189.2_C67_LASSOSUM_MGI_20200608/all.tsv /larsf/prsweb-data/cancerprsweb/releases/cancerprsweb_20200608/phewas/PRSWEB_PHECODE189.2_C67_LASSOSUM_MGI_20200608/exclusion.tsv 2020-06-08 prsweb-phecode189-2-ukbb-saige-hrc-x189-2-lassosum-mgi-20200608 prsweb-phecode189-2-ukbb-saige-hrc-x189-2-lassosum-mgi-20200608 PRSWEB_PHECODE189.2_UKBB-SAIGE-HRC-X189.2_LASSOSUM_MGI_20200608 Lassosum PRSWEB_PHECODE189.2_UKBB-SAIGE-HRC-X189.2_LASSOSUM_MGI_20200608 189.2 Cancer of bladder Binary ICD9 and ICD10 based PheWAS codes MGI Michigan Genomics Initiative lassosum UKB GWAS (PheCode) UKB_GWAS https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761 24359 0.00059 0.00365252 0.0921 0.538 0.517-0.557 OR 0.983 0.459-2.11 0.983 0.459-2.11 1.05 0.623-1.76 1.05 0.623-1.76 1.11 0.807-1.54 1.11 0.807-1.54 1.04 0.819-1.33 1.04 0.819-1.33 1.16 0.986-1.37 1.16 0.986-1.37 1.31 1.05-1.64 0.0176 1.46 1.17-1.81 0.000666 1.47 1.18-1.82 0.00057 True False False True Both 789 6833 GRCh37/hg19 s=1;Lambda=0.02976 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000616/ScoringFiles/ https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000616/ScoringFiles/ /larsf/prsweb-data/cancerprsweb/releases/cancerprsweb_20200608/phewas/PRSWEB_PHECODE189.2_UKBB-SAIGE-HRC-X189.2_LASSOSUM_MGI_20200608/all.tsv /larsf/prsweb-data/cancerprsweb/releases/cancerprsweb_20200608/phewas/PRSWEB_PHECODE189.2_UKBB-SAIGE-HRC-X189.2_LASSOSUM_MGI_20200608/exclusion.tsv 2020-06-08