prs_id slug legacy_id legacy_model prswebprefix trait_code trait_name trait_type description cohort cohort_label method gwas_source reference_label reference_url snp_count p_value pseudo_r2 brier_score mse aauc aauc_ci effect_metric top_effect_1 top_effect_1_ci top_or_1 top_or_1_ci top_effect_2 top_effect_2_ci top_or_2 top_or_2_ci top_effect_5 top_effect_5_ci top_or_5 top_or_5_ci top_effect_10 top_effect_10_ci top_or_10 top_or_10_ci top_effect_25 top_effect_25_ci top_or_25 top_or_25_ci q1_vs_q2_effect q1_vs_q2_effect_ci q1_vs_q2_p_value q1_vs_q3_effect q1_vs_q3_effect_ci q1_vs_q3_p_value q1_vs_q4_effect q1_vs_q4_effect_ci q1_vs_q4_p_value nominally_significant reversed_effect_warning underpowered_warning upload_to_portal sex cases controls genome_build tuning_parameter weights_external_url weights_url phewas_download_url exclusion_download_url last_updated prsweb-phecode190-20001-1030-p-5e-05-mgi-20200608 prsweb-phecode190-20001-1030-p-5e-05-mgi-20200608 PRSWEB_PHECODE190_20001-1030_P_5e-05_MGI_20200608 P_5e-05 PRSWEB_PHECODE190_20001-1030_P_5e-05_MGI_20200608 190 Cancer code, self-reported: eye and/or adnexal cancer Binary GWAS round 2: Results shared 1st August 2018. Imputed genotypes from HRC plus UK10K & 1000 Genomes reference panels as released by UK Biobank in March 2018. MGI Michigan Genomics Initiative Fixed threshold (5e-05) UKB GWAS (PHESANT) UKB_GWAS https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761 34 0.75 0.00725005 0.0837 0.492 0.414-0.565 OR 3.29 0.71-15.3 3.29 0.71-15.3 1.81 0.442-7.42 1.81 0.442-7.42 1.76 0.678-4.58 1.76 0.678-4.58 1.21 0.545-2.7 1.21 0.545-2.7 1.05 0.587-1.89 1.05 0.587-1.89 0.679 0.33-1.4 0.294 0.778 0.385-1.57 0.483 0.837 0.423-1.66 0.611 False False False False Both 62 610 GRCh37/hg19 P<=5e-05 2020-06-08 prsweb-phecode190-c3-eye-adnexa-p-5e-05-mgi-20200608 prsweb-phecode190-c3-eye-adnexa-p-5e-05-mgi-20200608 PRSWEB_PHECODE190_C3-EYE-ADNEXA_P_5e-05_MGI_20200608 P_5e-05 PRSWEB_PHECODE190_C3-EYE-ADNEXA_P_5e-05_MGI_20200608 190 Malignant neoplasm of eye and adnexa Binary GWAS round 2: Results shared 1st August 2018. Imputed genotypes from HRC plus UK10K & 1000 Genomes reference panels as released by UK Biobank in March 2018. MGI Michigan Genomics Initiative Fixed threshold (5e-05) UKB GWAS (FINNGEN) UKB_GWAS https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761 49 0.77 0.0070403 0.0837 0.501 0.425-0.577 OR 1.93 0.299-12.4 1.93 0.299-12.4 1.79 0.432-7.38 1.79 0.432-7.38 1.71 0.656-4.48 1.71 0.656-4.48 1.37 0.636-2.95 1.37 0.636-2.95 1.23 0.695-2.16 1.23 0.695-2.16 1.11 0.558-2.2 0.768 0.567 0.251-1.28 0.172 1.06 0.53-2.11 0.874 False False False False Both 62 610 GRCh37/hg19 P<=5e-05 2020-06-08 prsweb-phecode190-c69-p-5e-05-mgi-20200608 prsweb-phecode190-c69-p-5e-05-mgi-20200608 PRSWEB_PHECODE190_C69_P_5e-05_MGI_20200608 P_5e-05 PRSWEB_PHECODE190_C69_P_5e-05_MGI_20200608 190 Diagnoses - main ICD10: C69 Malignant neoplasm of eye and adnexa Binary GWAS round 2: Results shared 1st August 2018. Imputed genotypes from HRC plus UK10K & 1000 Genomes reference panels as released by UK Biobank in March 2018. MGI Michigan Genomics Initiative Fixed threshold (5e-05) UKB GWAS (ICD10) UKB_GWAS https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761 35 0.35 0.0029501 0.0837 0.534 0.464-0.611 OR 0 0-0 0 0-0 1.8 0.438-7.38 1.8 0.438-7.38 1.73 0.671-4.47 1.73 0.671-4.47 1.01 0.433-2.36 1.01 0.433-2.36 1.23 0.694-2.18 1.23 0.694-2.18 0.951 0.439-2.06 0.898 1.31 0.635-2.68 0.468 1.29 0.62-2.68 0.496 False False False False Both 62 610 GRCh37/hg19 P<=5e-05 2020-06-08 prsweb-phecode190-ukbb-saige-hrc-x190-p-5e-05-mgi-20200608 prsweb-phecode190-ukbb-saige-hrc-x190-p-5e-05-mgi-20200608 PRSWEB_PHECODE190_UKBB-SAIGE-HRC-X190_P_5e-05_MGI_20200608 P_5e-05 PRSWEB_PHECODE190_UKBB-SAIGE-HRC-X190_P_5e-05_MGI_20200608 190 Cancer of eye Binary ICD9 and ICD10 based PheWAS codes MGI Michigan Genomics Initiative Fixed threshold (5e-05) UKB GWAS (PheCode) UKB_GWAS https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761 71 0.88 0.000952131 0.0837 0.486 0.403-0.56 OR 0 0-0 0 0-0 1.78 0.432-7.31 1.78 0.432-7.31 2.09 0.844-5.18 2.09 0.844-5.18 1.76 0.859-3.6 1.76 0.859-3.6 1.06 0.589-1.89 1.06 0.589-1.89 0.874 0.43-1.78 0.71 0.832 0.408-1.69 0.611 0.926 0.46-1.86 0.829 False False False False Both 62 610 GRCh37/hg19 P<=5e-05 2020-06-08 prsweb-phecode190-c3-eye-adnexa-p-5e-06-mgi-20200608 prsweb-phecode190-c3-eye-adnexa-p-5e-06-mgi-20200608 PRSWEB_PHECODE190_C3-EYE-ADNEXA_P_5e-06_MGI_20200608 P_5e-06 PRSWEB_PHECODE190_C3-EYE-ADNEXA_P_5e-06_MGI_20200608 190 Malignant neoplasm of eye and adnexa Binary GWAS round 2: Results shared 1st August 2018. Imputed genotypes from HRC plus UK10K & 1000 Genomes reference panels as released by UK Biobank in March 2018. MGI Michigan Genomics Initiative Fixed threshold (5e-06) UKB GWAS (FINNGEN) UKB_GWAS https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761 7 0.93 0.00213657 0.0837 0.496 0.417-0.571 OR 1.86 0.286-12.1 1.86 0.286-12.1 1.04 0.182-5.95 1.04 0.182-5.95 1.41 0.506-3.95 1.41 0.506-3.95 1.02 0.436-2.37 1.02 0.436-2.37 0.97 0.536-1.76 0.97 0.536-1.76 1.73 0.823-3.62 0.149 1.37 0.632-2.98 0.423 1.39 0.637-3.05 0.406 False False False False Both 62 610 GRCh37/hg19 P<=5e-06 2020-06-08 prsweb-phecode190-c3-eye-adnexa-pt-mgi-20200608 prsweb-phecode190-c3-eye-adnexa-pt-mgi-20200608 PRSWEB_PHECODE190_C3-EYE-ADNEXA_PT_MGI_20200608 P&T PRSWEB_PHECODE190_C3-EYE-ADNEXA_PT_MGI_20200608 190 Malignant neoplasm of eye and adnexa Binary GWAS round 2: Results shared 1st August 2018. Imputed genotypes from HRC plus UK10K & 1000 Genomes reference panels as released by UK Biobank in March 2018. MGI Michigan Genomics Initiative P&T UKB GWAS (FINNGEN) UKB_GWAS https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761 49 0.77 0.0070403 0.0837 0.501 0.425-0.577 OR 1.93 0.299-12.4 1.93 0.299-12.4 1.79 0.432-7.38 1.79 0.432-7.38 1.71 0.656-4.48 1.71 0.656-4.48 1.37 0.636-2.95 1.37 0.636-2.95 1.23 0.695-2.16 1.23 0.695-2.16 1.11 0.558-2.2 0.768 0.567 0.251-1.28 0.172 1.06 0.53-2.11 0.874 False False False False Both 62 610 GRCh37/hg19 P<=5e-05 2020-06-08 prsweb-phecode190-20001-1030-prs-cs-mgi-20200608 prsweb-phecode190-20001-1030-prs-cs-mgi-20200608 PRSWEB_PHECODE190_20001-1030_PRS-CS_MGI_20200608 PRS-CS PRSWEB_PHECODE190_20001-1030_PRS-CS_MGI_20200608 190 Cancer code, self-reported: eye and/or adnexal cancer Binary GWAS round 2: Results shared 1st August 2018. Imputed genotypes from HRC plus UK10K & 1000 Genomes reference panels as released by UK Biobank in March 2018. MGI Michigan Genomics Initiative PRS-CS UKB GWAS (PHESANT) UKB_GWAS https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761 834009 0.027 0.00347171 0.0831 0.586 0.508-0.658 OR 4.74 1.2-18.7 4.74 1.2-18.7 3.39 1.1-10.5 3.39 1.1-10.5 1.75 0.679-4.54 1.75 0.679-4.54 1.8 0.884-3.69 1.8 0.884-3.69 1.67 0.971-2.87 1.67 0.971-2.87 1.5 0.644-3.52 0.346 2.13 0.95-4.76 0.0665 2.6 1.17-5.77 0.0191 True False False True Both 62 610 GRCh37/hg19 auto https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000617/ScoringFiles/ https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000617/ScoringFiles/ /larsf/prsweb-data/cancerprsweb/releases/cancerprsweb_20200608/phewas/PRSWEB_PHECODE190_20001-1030_PRS-CS_MGI_20200608/all.tsv /larsf/prsweb-data/cancerprsweb/releases/cancerprsweb_20200608/phewas/PRSWEB_PHECODE190_20001-1030_PRS-CS_MGI_20200608/exclusion.tsv 2020-06-08 prsweb-phecode190-c3-eye-adnexa-prs-cs-mgi-20200608 prsweb-phecode190-c3-eye-adnexa-prs-cs-mgi-20200608 PRSWEB_PHECODE190_C3-EYE-ADNEXA_PRS-CS_MGI_20200608 PRS-CS PRSWEB_PHECODE190_C3-EYE-ADNEXA_PRS-CS_MGI_20200608 190 Malignant neoplasm of eye and adnexa Binary GWAS round 2: Results shared 1st August 2018. Imputed genotypes from HRC plus UK10K & 1000 Genomes reference panels as released by UK Biobank in March 2018. MGI Michigan Genomics Initiative PRS-CS UKB GWAS (FINNGEN) UKB_GWAS https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761 849853 0.3 6.45946e-05 0.0836 0.546 0.47-0.622 OR 1.99 0.308-12.8 1.99 0.308-12.8 1.1 0.193-6.3 1.1 0.193-6.3 1.41 0.506-3.95 1.41 0.506-3.95 1.03 0.441-2.39 1.03 0.441-2.39 1.43 0.827-2.48 1.43 0.827-2.48 1.03 0.473-2.25 0.939 1.33 0.624-2.82 0.462 1.65 0.803-3.39 0.173 False False False False Both 62 610 GRCh37/hg19 auto 2020-06-08 prsweb-phecode190-c69-prs-cs-mgi-20200608 prsweb-phecode190-c69-prs-cs-mgi-20200608 PRSWEB_PHECODE190_C69_PRS-CS_MGI_20200608 PRS-CS PRSWEB_PHECODE190_C69_PRS-CS_MGI_20200608 190 Diagnoses - main ICD10: C69 Malignant neoplasm of eye and adnexa Binary GWAS round 2: Results shared 1st August 2018. Imputed genotypes from HRC plus UK10K & 1000 Genomes reference panels as released by UK Biobank in March 2018. MGI Michigan Genomics Initiative PRS-CS UKB GWAS (ICD10) UKB_GWAS https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761 911547 0.13 0.00109888 0.0834 0.545 0.47-0.613 OR 4.58 1.17-17.9 4.58 1.17-17.9 3.36 1.09-10.4 3.36 1.09-10.4 2.12 0.869-5.19 2.12 0.869-5.19 1.76 0.868-3.58 1.76 0.868-3.58 1.24 0.702-2.17 1.24 0.702-2.17 1.35 0.643-2.83 0.429 1.29 0.598-2.78 0.518 1.48 0.712-3.09 0.292 False False False False Both 62 610 GRCh37/hg19 auto 2020-06-08 prsweb-phecode190-ukbb-saige-hrc-x190-prs-cs-mgi-20200608 prsweb-phecode190-ukbb-saige-hrc-x190-prs-cs-mgi-20200608 PRSWEB_PHECODE190_UKBB-SAIGE-HRC-X190_PRS-CS_MGI_20200608 PRS-CS PRSWEB_PHECODE190_UKBB-SAIGE-HRC-X190_PRS-CS_MGI_20200608 190 Cancer of eye Binary ICD9 and ICD10 based PheWAS codes MGI Michigan Genomics Initiative PRS-CS UKB GWAS (PheCode) UKB_GWAS https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761 1119238 0.47 0.000165598 0.0837 0.53 0.459-0.603 OR 1.88 0.29-12.1 1.88 0.29-12.1 1.03 0.179-5.95 1.03 0.179-5.95 1.07 0.344-3.33 1.07 0.344-3.33 0.852 0.344-2.11 0.852 0.344-2.11 1.06 0.588-1.9 1.06 0.588-1.9 1.55 0.705-3.42 0.274 1.78 0.831-3.83 0.138 1.62 0.736-3.56 0.23 False False False False Both 62 610 GRCh37/hg19 auto 2020-06-08 prsweb-phecode190-20001-1030-lassosum-mgi-20200608 prsweb-phecode190-20001-1030-lassosum-mgi-20200608 PRSWEB_PHECODE190_20001-1030_LASSOSUM_MGI_20200608 Lassosum PRSWEB_PHECODE190_20001-1030_LASSOSUM_MGI_20200608 190 Cancer code, self-reported: eye and/or adnexal cancer Binary GWAS round 2: Results shared 1st August 2018. Imputed genotypes from HRC plus UK10K & 1000 Genomes reference panels as released by UK Biobank in March 2018. MGI Michigan Genomics Initiative lassosum UKB GWAS (PHESANT) UKB_GWAS https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761 19193 0.15 0.00467078 0.0835 0.561 0.485-0.636 OR 0 0-0 0 0-0 1.88 0.458-7.75 1.88 0.458-7.75 1.43 0.512-3.97 1.43 0.512-3.97 1.21 0.545-2.71 1.21 0.545-2.71 1.44 0.829-2.5 1.44 0.829-2.5 0.667 0.295-1.5 0.329 1.47 0.716-3.01 0.295 1.39 0.696-2.78 0.35 False False False False Both 62 610 GRCh37/hg19 s=0.2;Lambda=0.1 2020-06-08 prsweb-phecode190-c3-eye-adnexa-lassosum-mgi-20200608 prsweb-phecode190-c3-eye-adnexa-lassosum-mgi-20200608 PRSWEB_PHECODE190_C3-EYE-ADNEXA_LASSOSUM_MGI_20200608 Lassosum PRSWEB_PHECODE190_C3-EYE-ADNEXA_LASSOSUM_MGI_20200608 190 Malignant neoplasm of eye and adnexa Binary GWAS round 2: Results shared 1st August 2018. Imputed genotypes from HRC plus UK10K & 1000 Genomes reference panels as released by UK Biobank in March 2018. MGI Michigan Genomics Initiative lassosum UKB GWAS (FINNGEN) UKB_GWAS https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761 195920 0.37 0.0146436 0.0837 0.534 0.456-0.608 OR 1.91 0.296-12.4 1.91 0.296-12.4 1.78 0.432-7.3 1.78 0.432-7.3 1.05 0.334-3.3 1.05 0.334-3.3 1.01 0.432-2.36 1.01 0.432-2.36 1.24 0.702-2.18 1.24 0.702-2.18 1.86 0.879-3.94 0.104 1.1 0.488-2.49 0.816 1.6 0.752-3.4 0.223 False False False False Both 62 610 GRCh37/hg19 s=0.5;Lambda=0.04833 2020-06-08 prsweb-phecode190-c69-lassosum-mgi-20200608 prsweb-phecode190-c69-lassosum-mgi-20200608 PRSWEB_PHECODE190_C69_LASSOSUM_MGI_20200608 Lassosum PRSWEB_PHECODE190_C69_LASSOSUM_MGI_20200608 190 Diagnoses - main ICD10: C69 Malignant neoplasm of eye and adnexa Binary GWAS round 2: Results shared 1st August 2018. Imputed genotypes from HRC plus UK10K & 1000 Genomes reference panels as released by UK Biobank in March 2018. MGI Michigan Genomics Initiative lassosum UKB GWAS (ICD10) UKB_GWAS https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761 1496730 0.28 0.013048 0.0836 0.54 0.461-0.621 OR 1.82 0.268-12.4 1.82 0.268-12.4 1.76 0.412-7.5 1.76 0.412-7.5 2.14 0.863-5.33 2.14 0.863-5.33 2.01 1-4.04 2.01 1-4.04 1.65 0.96-2.84 1.65 0.96-2.84 0.835 0.406-1.72 0.623 0.528 0.238-1.17 0.116 1.31 0.679-2.51 0.424 False False False False Both 62 610 GRCh37/hg19 s=0.2;Lambda=0.004281 2020-06-08 prsweb-phecode190-ukbb-saige-hrc-x190-lassosum-mgi-20200608 prsweb-phecode190-ukbb-saige-hrc-x190-lassosum-mgi-20200608 PRSWEB_PHECODE190_UKBB-SAIGE-HRC-X190_LASSOSUM_MGI_20200608 Lassosum PRSWEB_PHECODE190_UKBB-SAIGE-HRC-X190_LASSOSUM_MGI_20200608 190 Cancer of eye Binary ICD9 and ICD10 based PheWAS codes MGI Michigan Genomics Initiative lassosum UKB GWAS (PheCode) UKB_GWAS https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761 2397847 0.12 0.0110053 0.0834 0.547 0.473-0.62 OR 1.93 0.297-12.5 1.93 0.297-12.5 1.8 0.437-7.4 1.8 0.437-7.4 2.5 1.06-5.89 2.5 1.06-5.89 2.03 1.01-4.08 2.03 1.01-4.08 1.25 0.708-2.21 1.25 0.708-2.21 1.76 0.832-3.71 0.14 1.29 0.592-2.8 0.523 1.54 0.72-3.27 0.267 False False False False Both 62 610 GRCh37/hg19 s=0.5;Lambda=0.008859 2020-06-08