prs_id slug legacy_id legacy_model prswebprefix trait_code trait_name trait_type description cohort cohort_label method gwas_source reference_label reference_url snp_count p_value pseudo_r2 brier_score mse aauc aauc_ci effect_metric top_effect_1 top_effect_1_ci top_or_1 top_or_1_ci top_effect_2 top_effect_2_ci top_or_2 top_or_2_ci top_effect_5 top_effect_5_ci top_or_5 top_or_5_ci top_effect_10 top_effect_10_ci top_or_10 top_or_10_ci top_effect_25 top_effect_25_ci top_or_25 top_or_25_ci q1_vs_q2_effect q1_vs_q2_effect_ci q1_vs_q2_p_value q1_vs_q3_effect q1_vs_q3_effect_ci q1_vs_q3_p_value q1_vs_q4_effect q1_vs_q4_effect_ci q1_vs_q4_p_value nominally_significant reversed_effect_warning underpowered_warning upload_to_portal sex cases controls genome_build tuning_parameter weights_external_url weights_url phewas_download_url exclusion_download_url last_updated prsweb-phecode191-1-c3-eye-brain-neuro-p-5e-05-mgi-20200608 prsweb-phecode191-1-c3-eye-brain-neuro-p-5e-05-mgi-20200608 PRSWEB_PHECODE191.1_C3-EYE-BRAIN-NEURO_P_5e-05_MGI_20200608 P_5e-05 PRSWEB_PHECODE191.1_C3-EYE-BRAIN-NEURO_P_5e-05_MGI_20200608 191.1 Malignant neoplasm of eye, brain and central nervous system Binary GWAS round 2: Results shared 1st August 2018. Imputed genotypes from HRC plus UK10K & 1000 Genomes reference panels as released by UK Biobank in March 2018. MGI Michigan Genomics Initiative Fixed threshold (5e-05) UKB GWAS (FINNGEN) UKB_GWAS https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761 105 0.086 0.000102431 0.0826 0.526 0.488-0.561 OR 1.22 0.394-3.79 1.22 0.394-3.79 0.989 0.406-2.41 0.989 0.406-2.41 0.978 0.551-1.73 0.978 0.551-1.73 1.29 0.883-1.88 1.29 0.883-1.88 1.24 0.944-1.63 1.24 0.944-1.63 1.06 0.738-1.53 0.749 1.15 0.805-1.65 0.438 1.34 0.944-1.89 0.102 False False False False Both 274 2740 GRCh37/hg19 P<=5e-05 2020-06-08 prsweb-phecode191-1-gwas-catalog-r2019-05-03-x191-1-p-5e-05-mgi-20200608 prsweb-phecode191-1-gwas-catalog-r2019-05-03-x191-1-p-5e-05-mgi-20200608 PRSWEB_PHECODE191.1_GWAS-Catalog-r2019-05-03-X191.1_P_5e-05_MGI_20200608 P_5e-05 PRSWEB_PHECODE191.1_GWAS-Catalog-r2019-05-03-X191.1_P_5e-05_MGI_20200608 191.1 Glioma;Non-glioblastoma glioma;Glioma (high-grade) Binary 36 unique SNPs MGI Michigan Genomics Initiative Fixed threshold (5e-05) GWAS Catalog (2019-05-03) 19578366;19578367;21531791;22886559;24908248;26424050;28346443 https://www.ncbi.nlm.nih.gov/pubmed/?term=19578366+19578367+21531791+22886559+24908248+26424050+28346443 28 0.34 0.00725184 0.0826 0.51 0.474-0.545 OR 0.875 0.235-3.26 0.875 0.235-3.26 0.991 0.407-2.41 0.991 0.407-2.41 0.678 0.347-1.32 0.678 0.347-1.32 1.08 0.722-1.61 1.08 0.722-1.61 1.26 0.961-1.66 1.26 0.961-1.66 0.949 0.664-1.36 0.776 0.958 0.67-1.37 0.813 1.21 0.864-1.71 0.264 False False False False Both 274 2740 GRCh37/hg19 P<=5e-05 2020-06-08 prsweb-phecode191-1-ukbb-saige-hrc-x191-1-p-5e-05-mgi-20200608 prsweb-phecode191-1-ukbb-saige-hrc-x191-1-p-5e-05-mgi-20200608 PRSWEB_PHECODE191.1_UKBB-SAIGE-HRC-X191.1_P_5e-05_MGI_20200608 P_5e-05 PRSWEB_PHECODE191.1_UKBB-SAIGE-HRC-X191.1_P_5e-05_MGI_20200608 191.1 Cancer of brain and nervous system Binary ICD9 and ICD10 based PheWAS codes MGI Michigan Genomics Initiative Fixed threshold (5e-05) UKB GWAS (PheCode) UKB_GWAS https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761 114 0.46 0.00301187 0.0826 0.506 0.472-0.54 OR 2.31 0.967-5.53 2.31 0.967-5.53 1.36 0.625-2.95 1.36 0.625-2.95 1.06 0.606-1.84 1.06 0.606-1.84 1.16 0.788-1.72 1.16 0.788-1.72 1.04 0.78-1.37 1.04 0.78-1.37 1.11 0.777-1.57 0.578 1.11 0.779-1.58 0.567 1.09 0.768-1.55 0.627 False False False False Both 274 2740 GRCh37/hg19 P<=5e-05 2020-06-08 prsweb-phecode191-1-gwas-catalog-r2019-05-03-x191-1-p-5e-06-mgi-20200608 prsweb-phecode191-1-gwas-catalog-r2019-05-03-x191-1-p-5e-06-mgi-20200608 PRSWEB_PHECODE191.1_GWAS-Catalog-r2019-05-03-X191.1_P_5e-06_MGI_20200608 P_5e-06 PRSWEB_PHECODE191.1_GWAS-Catalog-r2019-05-03-X191.1_P_5e-06_MGI_20200608 191.1 Glioma;Non-glioblastoma glioma;Glioma (high-grade) Binary 36 unique SNPs MGI Michigan Genomics Initiative Fixed threshold (5e-06) GWAS Catalog (2019-05-03) 19578366;19578367;21531791;22886559;24908248;26424050;28346443 https://www.ncbi.nlm.nih.gov/pubmed/?term=19578366+19578367+21531791+22886559+24908248+26424050+28346443 28 0.34 0.00725184 0.0826 0.51 0.474-0.545 OR 0.875 0.235-3.26 0.875 0.235-3.26 0.991 0.407-2.41 0.991 0.407-2.41 0.678 0.347-1.32 0.678 0.347-1.32 1.08 0.722-1.61 1.08 0.722-1.61 1.26 0.961-1.66 1.26 0.961-1.66 0.949 0.664-1.36 0.776 0.958 0.67-1.37 0.813 1.21 0.864-1.71 0.264 False False False False Both 274 2740 GRCh37/hg19 P<=5e-06 2020-06-08 prsweb-phecode191-1-ukbb-saige-hrc-x191-1-p-5e-06-mgi-20200608 prsweb-phecode191-1-ukbb-saige-hrc-x191-1-p-5e-06-mgi-20200608 PRSWEB_PHECODE191.1_UKBB-SAIGE-HRC-X191.1_P_5e-06_MGI_20200608 P_5e-06 PRSWEB_PHECODE191.1_UKBB-SAIGE-HRC-X191.1_P_5e-06_MGI_20200608 191.1 Cancer of brain and nervous system Binary ICD9 and ICD10 based PheWAS codes MGI Michigan Genomics Initiative Fixed threshold (5e-06) UKB GWAS (PheCode) UKB_GWAS https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761 17 0.015 0.000227147 0.0825 0.53 0.495-0.563 OR 1.22 0.393-3.78 1.22 0.393-3.78 1.17 0.514-2.68 1.17 0.514-2.68 1.37 0.827-2.26 1.37 0.827-2.26 1.12 0.753-1.66 1.12 0.753-1.66 1.26 0.963-1.66 1.26 0.963-1.66 1.05 0.718-1.53 0.812 1.41 0.985-2.01 0.0603 1.45 1.02-2.06 0.041 True False False False Both 274 2740 GRCh37/hg19 P<=5e-06 2020-06-08 prsweb-phecode191-1-gwas-catalog-r2019-05-03-x191-1-p-5e-07-mgi-20200608 prsweb-phecode191-1-gwas-catalog-r2019-05-03-x191-1-p-5e-07-mgi-20200608 PRSWEB_PHECODE191.1_GWAS-Catalog-r2019-05-03-X191.1_P_5e-07_MGI_20200608 P_5e-07 PRSWEB_PHECODE191.1_GWAS-Catalog-r2019-05-03-X191.1_P_5e-07_MGI_20200608 191.1 Glioma;Non-glioblastoma glioma;Glioma (high-grade) Binary 36 unique SNPs MGI Michigan Genomics Initiative Fixed threshold (5e-07) GWAS Catalog (2019-05-03) 19578366;19578367;21531791;22886559;24908248;26424050;28346443 https://www.ncbi.nlm.nih.gov/pubmed/?term=19578366+19578367+21531791+22886559+24908248+26424050+28346443 25 0.3 0.00709871 0.0826 0.51 0.474-0.544 OR 1.23 0.397-3.81 1.23 0.397-3.81 0.99 0.407-2.41 0.99 0.407-2.41 0.679 0.348-1.33 0.679 0.348-1.33 1.16 0.785-1.72 1.16 0.785-1.72 1.24 0.943-1.63 1.24 0.943-1.63 1.01 0.715-1.44 0.934 0.88 0.612-1.26 0.488 1.2 0.851-1.68 0.302 False False False False Both 274 2740 GRCh37/hg19 P<=5e-07 2020-06-08 prsweb-phecode191-1-gwas-catalog-r2019-05-03-x191-1-p-5e-09-mgi-20200608 prsweb-phecode191-1-gwas-catalog-r2019-05-03-x191-1-p-5e-09-mgi-20200608 PRSWEB_PHECODE191.1_GWAS-Catalog-r2019-05-03-X191.1_P_5e-09_MGI_20200608 P_5e-09 PRSWEB_PHECODE191.1_GWAS-Catalog-r2019-05-03-X191.1_P_5e-09_MGI_20200608 191.1 Glioma;Non-glioblastoma glioma;Glioma (high-grade) Binary 36 unique SNPs MGI Michigan Genomics Initiative Fixed threshold (5e-09) GWAS Catalog (2019-05-03) 19578366;19578367;21531791;22886559;24908248;26424050;28346443 https://www.ncbi.nlm.nih.gov/pubmed/?term=19578366+19578367+21531791+22886559+24908248+26424050+28346443 20 0.58 0.00473546 0.0826 0.501 0.465-0.535 OR 0.873 0.234-3.25 0.873 0.234-3.25 1.17 0.511-2.67 1.17 0.511-2.67 0.976 0.55-1.73 0.976 0.55-1.73 1.12 0.753-1.66 1.12 0.753-1.66 1.07 0.809-1.42 1.07 0.809-1.42 0.75 0.524-1.07 0.115 0.92 0.653-1.29 0.631 0.965 0.688-1.35 0.839 False False False False Both 274 2740 GRCh37/hg19 P<=5e-09 2020-06-08 prsweb-phecode191-1-gwas-catalog-r2019-05-03-x191-1-p-5e-08-mgi-20200608 prsweb-phecode191-1-gwas-catalog-r2019-05-03-x191-1-p-5e-08-mgi-20200608 PRSWEB_PHECODE191.1_GWAS-Catalog-r2019-05-03-X191.1_P_5e-08_MGI_20200608 P_5e-08 PRSWEB_PHECODE191.1_GWAS-Catalog-r2019-05-03-X191.1_P_5e-08_MGI_20200608 191.1 Glioma;Non-glioblastoma glioma;Glioma (high-grade) Binary 36 unique SNPs MGI Michigan Genomics Initiative GWAS Hits GWAS Catalog (2019-05-03) 19578366;19578367;21531791;22886559;24908248;26424050;28346443 https://www.ncbi.nlm.nih.gov/pubmed/?term=19578366+19578367+21531791+22886559+24908248+26424050+28346443 23 0.28 0.00579417 0.0826 0.511 0.476-0.546 OR 0.872 0.234-3.25 0.872 0.234-3.25 0.993 0.408-2.41 0.993 0.408-2.41 0.903 0.499-1.63 0.903 0.499-1.63 1.12 0.752-1.66 1.12 0.752-1.66 1.13 0.857-1.5 1.13 0.857-1.5 1.09 0.767-1.55 0.627 1.01 0.706-1.45 0.956 1.17 0.824-1.66 0.383 False False False False Both 274 2740 GRCh37/hg19 P<=5e-08 2020-06-08 prsweb-phecode191-1-c3-eye-brain-neuro-pt-mgi-20200608 prsweb-phecode191-1-c3-eye-brain-neuro-pt-mgi-20200608 PRSWEB_PHECODE191.1_C3-EYE-BRAIN-NEURO_PT_MGI_20200608 P&T PRSWEB_PHECODE191.1_C3-EYE-BRAIN-NEURO_PT_MGI_20200608 191.1 Malignant neoplasm of eye, brain and central nervous system Binary GWAS round 2: Results shared 1st August 2018. Imputed genotypes from HRC plus UK10K & 1000 Genomes reference panels as released by UK Biobank in March 2018. MGI Michigan Genomics Initiative P&T UKB GWAS (FINNGEN) UKB_GWAS https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761 36 0.38 0.000490337 0.0826 0.508 0.47-0.543 OR 0 0-0 0 0-0 0.623 0.209-1.86 0.623 0.209-1.86 1.29 0.77-2.15 1.29 0.77-2.15 1.33 0.917-1.94 1.33 0.917-1.94 1.16 0.878-1.53 1.16 0.878-1.53 0.802 0.564-1.14 0.219 0.836 0.59-1.18 0.313 1 0.718-1.4 0.985 False False False False Both 274 2740 GRCh37/hg19 P<=1.26e-05 2020-06-08 prsweb-phecode191-1-gwas-catalog-r2019-05-03-x191-1-pt-mgi-20200608 prsweb-phecode191-1-gwas-catalog-r2019-05-03-x191-1-pt-mgi-20200608 PRSWEB_PHECODE191.1_GWAS-Catalog-r2019-05-03-X191.1_PT_MGI_20200608 P&T PRSWEB_PHECODE191.1_GWAS-Catalog-r2019-05-03-X191.1_PT_MGI_20200608 191.1 Glioma;Non-glioblastoma glioma;Glioma (high-grade) Binary 36 unique SNPs MGI Michigan Genomics Initiative P&T GWAS Catalog (2019-05-03) 19578366;19578367;21531791;22886559;24908248;26424050;28346443 https://www.ncbi.nlm.nih.gov/pubmed/?term=19578366+19578367+21531791+22886559+24908248+26424050+28346443 28 0.34 0.00725184 0.0826 0.51 0.474-0.545 OR 0.875 0.235-3.26 0.875 0.235-3.26 0.991 0.407-2.41 0.991 0.407-2.41 0.678 0.347-1.32 0.678 0.347-1.32 1.08 0.722-1.61 1.08 0.722-1.61 1.26 0.961-1.66 1.26 0.961-1.66 0.949 0.664-1.36 0.776 0.958 0.67-1.37 0.813 1.21 0.864-1.71 0.264 False False False False Both 274 2740 GRCh37/hg19 P<=5e-06 2020-06-08 prsweb-phecode191-1-c3-eye-brain-neuro-prs-cs-mgi-20200608 prsweb-phecode191-1-c3-eye-brain-neuro-prs-cs-mgi-20200608 PRSWEB_PHECODE191.1_C3-EYE-BRAIN-NEURO_PRS-CS_MGI_20200608 PRS-CS PRSWEB_PHECODE191.1_C3-EYE-BRAIN-NEURO_PRS-CS_MGI_20200608 191.1 Malignant neoplasm of eye, brain and central nervous system Binary GWAS round 2: Results shared 1st August 2018. Imputed genotypes from HRC plus UK10K & 1000 Genomes reference panels as released by UK Biobank in March 2018. MGI Michigan Genomics Initiative PRS-CS UKB GWAS (FINNGEN) UKB_GWAS https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761 1072894 0.22 0.000842839 0.0826 0.526 0.49-0.562 OR 0.876 0.235-3.27 0.876 0.235-3.27 0.996 0.409-2.43 0.996 0.409-2.43 1.22 0.718-2.06 1.22 0.718-2.06 0.962 0.633-1.46 0.962 0.633-1.46 1.1 0.829-1.45 1.1 0.829-1.45 1.23 0.854-1.76 0.268 1.31 0.914-1.87 0.142 1.29 0.899-1.84 0.167 False False False False Both 274 2740 GRCh37/hg19 auto 2020-06-08 prsweb-phecode191-1-ukbb-saige-hrc-x191-1-lassosum-mgi-20200608 prsweb-phecode191-1-ukbb-saige-hrc-x191-1-lassosum-mgi-20200608 PRSWEB_PHECODE191.1_UKBB-SAIGE-HRC-X191.1_LASSOSUM_MGI_20200608 Lassosum PRSWEB_PHECODE191.1_UKBB-SAIGE-HRC-X191.1_LASSOSUM_MGI_20200608 191.1 Cancer of brain and nervous system Binary ICD9 and ICD10 based PheWAS codes MGI Michigan Genomics Initiative lassosum UKB GWAS (PheCode) UKB_GWAS https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761 43 0.28 0.00796085 0.0826 0.506 0.47-0.538 OR 1.23 0.396-3.8 1.23 0.396-3.8 1.17 0.512-2.67 1.17 0.512-2.67 1.44 0.88-2.35 1.44 0.88-2.35 1.29 0.882-1.88 1.29 0.882-1.88 0.993 0.746-1.32 0.993 0.746-1.32 1.26 0.885-1.8 0.199 1.19 0.834-1.7 0.338 1.13 0.788-1.62 0.507 False False False False Both 274 2740 GRCh37/hg19 s=0.5;Lambda=0.1 2020-06-08