prs_id	slug	legacy_id	legacy_model	prswebprefix	trait_code	trait_name	trait_type	description	cohort	cohort_label	method	gwas_source	reference_label	reference_url	snp_count	p_value	pseudo_r2	brier_score	mse	aauc	aauc_ci	effect_metric	top_effect_1	top_effect_1_ci	top_or_1	top_or_1_ci	top_effect_2	top_effect_2_ci	top_or_2	top_or_2_ci	top_effect_5	top_effect_5_ci	top_or_5	top_or_5_ci	top_effect_10	top_effect_10_ci	top_or_10	top_or_10_ci	top_effect_25	top_effect_25_ci	top_or_25	top_or_25_ci	q1_vs_q2_effect	q1_vs_q2_effect_ci	q1_vs_q2_p_value	q1_vs_q3_effect	q1_vs_q3_effect_ci	q1_vs_q3_p_value	q1_vs_q4_effect	q1_vs_q4_effect_ci	q1_vs_q4_p_value	nominally_significant	reversed_effect_warning	underpowered_warning	upload_to_portal	sex	cases	controls	genome_build	tuning_parameter	weights_external_url	weights_url	phewas_download_url	exclusion_download_url	last_updated
prsweb-phecode193-20001-1065-p-5e-05-mgi-20200608	prsweb-phecode193-20001-1065-p-5e-05-mgi-20200608	PRSWEB_PHECODE193_20001-1065_P_5e-05_MGI_20200608	P_5e-05	PRSWEB_PHECODE193_20001-1065_P_5e-05_MGI_20200608	193	Cancer code, self-reported: thyroid cancer	Binary	GWAS round 2: Results shared 1st August 2018. Imputed genotypes from HRC plus UK10K & 1000 Genomes reference panels as released by UK Biobank in March 2018.	MGI	Michigan Genomics Initiative	Fixed threshold (5e-05)	UKB GWAS (PHESANT)	UKB_GWAS	https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761	69	0.0068	0.0019543	0.0827		0.534	0.505-0.565	OR	1.13	0.42-3.04	1.13	0.42-3.04	0.948	0.444-2.02	0.948	0.444-2.02	1.31	0.858-2.02	1.31	0.858-2.02	1.33	0.972-1.82	1.33	0.972-1.82	1.21	0.962-1.53	1.21	0.962-1.53	1.02	0.752-1.4	0.878	1.22	0.907-1.65	0.187	1.32	0.981-1.77	0.0674	True	False	False	False	Both	389	3881	GRCh37/hg19	P<=5e-05					2020-06-08
prsweb-phecode193-c3-thyroid-gland-p-5e-05-mgi-20200608	prsweb-phecode193-c3-thyroid-gland-p-5e-05-mgi-20200608	PRSWEB_PHECODE193_C3-THYROID-GLAND_P_5e-05_MGI_20200608	P_5e-05	PRSWEB_PHECODE193_C3-THYROID-GLAND_P_5e-05_MGI_20200608	193	Malignant neoplasm of thyroid gland	Binary	GWAS round 2: Results shared 1st August 2018. Imputed genotypes from HRC plus UK10K & 1000 Genomes reference panels as released by UK Biobank in March 2018.	MGI	Michigan Genomics Initiative	Fixed threshold (5e-05)	UKB GWAS (FINNGEN)	UKB_GWAS	https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761	96	0.016	0.00422867	0.0827		0.532	0.503-0.561	OR	1.65	0.708-3.83	1.65	0.708-3.83	1.34	0.696-2.58	1.34	0.696-2.58	1.49	0.988-2.23	1.49	0.988-2.23	1.46	1.07-1.98	1.46	1.07-1.98	1.17	0.928-1.48	1.17	0.928-1.48	1.1	0.808-1.5	0.538	1.35	0.998-1.81	0.0517	1.35	0.997-1.82	0.0526	True	False	False	False	Both	389	3881	GRCh37/hg19	P<=5e-05					2020-06-08
prsweb-phecode193-c73-p-5e-05-mgi-20200608	prsweb-phecode193-c73-p-5e-05-mgi-20200608	PRSWEB_PHECODE193_C73_P_5e-05_MGI_20200608	P_5e-05	PRSWEB_PHECODE193_C73_P_5e-05_MGI_20200608	193	Diagnoses - main ICD10: C73 Malignant neoplasm of thyroid gland	Binary	GWAS round 2: Results shared 1st August 2018. Imputed genotypes from HRC plus UK10K & 1000 Genomes reference panels as released by UK Biobank in March 2018.	MGI	Michigan Genomics Initiative	Fixed threshold (5e-05)	UKB GWAS (ICD10)	UKB_GWAS	https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761	76	0.054	0.00674073	0.0827		0.527	0.494-0.558	OR	1.13	0.42-3.04	1.13	0.42-3.04	1.34	0.694-2.57	1.34	0.694-2.57	1.26	0.817-1.95	1.26	0.817-1.95	1.64	1.23-2.2	1.64	1.23-2.2	1.4	1.12-1.76	1.4	1.12-1.76	0.937	0.692-1.27	0.671	0.879	0.647-1.19	0.408	1.3	0.984-1.73	0.0642	False	False	False	False	Both	389	3881	GRCh37/hg19	P<=5e-05					2020-06-08
prsweb-phecode193-gwas-catalog-r2019-05-03-x193-p-5e-05-mgi-20200608	prsweb-phecode193-gwas-catalog-r2019-05-03-x193-p-5e-05-mgi-20200608	PRSWEB_PHECODE193_GWAS-Catalog-r2019-05-03-X193_P_5e-05_MGI_20200608	P_5e-05	PRSWEB_PHECODE193_GWAS-Catalog-r2019-05-03-X193_P_5e-05_MGI_20200608	193	Thyroid cancer	Binary	19 unique SNPs	MGI	Michigan Genomics Initiative	Fixed threshold (5e-05)	GWAS Catalog (2019-05-03)	19198613;22267200;23894154;25855579;28195142	https://www.ncbi.nlm.nih.gov/pubmed/?term=19198613+22267200+23894154+25855579+28195142	11	2.3e-19	0.0387304	0.0811		0.63	0.601-0.658	OR	3.26	1.69-6.26	3.26	1.69-6.26	3.12	1.94-5.02	3.12	1.94-5.02	2.68	1.92-3.74	2.68	1.92-3.74	2.63	2.03-3.41	2.63	2.03-3.41	2.33	1.88-2.88	2.33	1.88-2.88	1.45	1.01-2.1	0.0448	1.9	1.34-2.69	0.000338	3.41	2.46-4.72	1.55e-13	True	False	False	False	Both	389	3881	GRCh37/hg19	P<=5e-05					2020-06-08
prsweb-phecode193-ukbb-saige-hrc-x193-p-5e-05-mgi-20200608	prsweb-phecode193-ukbb-saige-hrc-x193-p-5e-05-mgi-20200608	PRSWEB_PHECODE193_UKBB-SAIGE-HRC-X193_P_5e-05_MGI_20200608	P_5e-05	PRSWEB_PHECODE193_UKBB-SAIGE-HRC-X193_P_5e-05_MGI_20200608	193	Thyroid cancer	Binary	ICD9 and ICD10 based PheWAS codes	MGI	Michigan Genomics Initiative	Fixed threshold (5e-05)	UKB GWAS (PheCode)	UKB_GWAS	https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761	86	0.0076	0.00253866	0.0827		0.529	0.498-0.558	OR	1.92	0.865-4.24	1.92	0.865-4.24	1.6	0.873-2.94	1.6	0.873-2.94	1.72	1.16-2.53	1.72	1.16-2.53	1.49	1.1-2.01	1.49	1.1-2.01	1.21	0.963-1.53	1.21	0.963-1.53	1.25	0.916-1.7	0.16	1.29	0.951-1.76	0.101	1.41	1.04-1.9	0.0269	True	False	False	False	Both	389	3881	GRCh37/hg19	P<=5e-05					2020-06-08
prsweb-phecode193-20001-1065-p-5e-06-mgi-20200608	prsweb-phecode193-20001-1065-p-5e-06-mgi-20200608	PRSWEB_PHECODE193_20001-1065_P_5e-06_MGI_20200608	P_5e-06	PRSWEB_PHECODE193_20001-1065_P_5e-06_MGI_20200608	193	Cancer code, self-reported: thyroid cancer	Binary	GWAS round 2: Results shared 1st August 2018. Imputed genotypes from HRC plus UK10K & 1000 Genomes reference panels as released by UK Biobank in March 2018.	MGI	Michigan Genomics Initiative	Fixed threshold (5e-06)	UKB GWAS (PHESANT)	UKB_GWAS	https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761	8	0.0041	0.00738545	0.0826		0.529	0.496-0.559	OR	2.44	1.18-5.02	2.44	1.18-5.02	1.74	0.964-3.13	1.74	0.964-3.13	1.71	1.16-2.52	1.71	1.16-2.52	1.49	1.1-2.01	1.49	1.1-2.01	1.32	1.05-1.66	1.32	1.05-1.66	1.1	0.801-1.5	0.566	1.28	0.943-1.73	0.114	1.48	1.1-1.99	0.00902	True	False	False	False	Both	389	3881	GRCh37/hg19	P<=5e-06					2020-06-08
prsweb-phecode193-c3-thyroid-gland-p-5e-06-mgi-20200608	prsweb-phecode193-c3-thyroid-gland-p-5e-06-mgi-20200608	PRSWEB_PHECODE193_C3-THYROID-GLAND_P_5e-06_MGI_20200608	P_5e-06	PRSWEB_PHECODE193_C3-THYROID-GLAND_P_5e-06_MGI_20200608	193	Malignant neoplasm of thyroid gland	Binary	GWAS round 2: Results shared 1st August 2018. Imputed genotypes from HRC plus UK10K & 1000 Genomes reference panels as released by UK Biobank in March 2018.	MGI	Michigan Genomics Initiative	Fixed threshold (5e-06)	UKB GWAS (FINNGEN)	UKB_GWAS	https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761	11	3.4e-06	0.0171123	0.0824		0.56	0.53-0.59	OR	2.42	1.17-4.98	2.42	1.17-4.98	1.73	0.96-3.12	1.73	0.96-3.12	1.48	0.987-2.23	1.48	0.987-2.23	1.58	1.18-2.13	1.58	1.18-2.13	1.39	1.11-1.74	1.39	1.11-1.74	1.33	0.959-1.85	0.0873	1.69	1.23-2.31	0.00107	1.85	1.36-2.52	9.79e-05	True	False	False	False	Both	389	3881	GRCh37/hg19	P<=5e-06					2020-06-08
prsweb-phecode193-c73-p-5e-06-mgi-20200608	prsweb-phecode193-c73-p-5e-06-mgi-20200608	PRSWEB_PHECODE193_C73_P_5e-06_MGI_20200608	P_5e-06	PRSWEB_PHECODE193_C73_P_5e-06_MGI_20200608	193	Diagnoses - main ICD10: C73 Malignant neoplasm of thyroid gland	Binary	GWAS round 2: Results shared 1st August 2018. Imputed genotypes from HRC plus UK10K & 1000 Genomes reference panels as released by UK Biobank in March 2018.	MGI	Michigan Genomics Initiative	Fixed threshold (5e-06)	UKB GWAS (ICD10)	UKB_GWAS	https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761	15	0.093	0.00796019	0.0827		0.514	0.483-0.546	OR	2.42	1.17-4.98	2.42	1.17-4.98	1.73	0.957-3.12	1.73	0.957-3.12	1.42	0.94-2.16	1.42	0.94-2.16	1.21	0.875-1.67	1.21	0.875-1.67	1.24	0.988-1.56	1.24	0.988-1.56	1.15	0.851-1.55	0.368	1.01	0.741-1.37	0.964	1.31	0.981-1.76	0.0666	False	False	False	False	Both	389	3881	GRCh37/hg19	P<=5e-06					2020-06-08
prsweb-phecode193-gwas-catalog-r2019-05-03-x193-p-5e-06-mgi-20200608	prsweb-phecode193-gwas-catalog-r2019-05-03-x193-p-5e-06-mgi-20200608	PRSWEB_PHECODE193_GWAS-Catalog-r2019-05-03-X193_P_5e-06_MGI_20200608	P_5e-06	PRSWEB_PHECODE193_GWAS-Catalog-r2019-05-03-X193_P_5e-06_MGI_20200608	193	Thyroid cancer	Binary	19 unique SNPs	MGI	Michigan Genomics Initiative	Fixed threshold (5e-06)	GWAS Catalog (2019-05-03)	19198613;22267200;23894154;25855579;28195142	https://www.ncbi.nlm.nih.gov/pubmed/?term=19198613+22267200+23894154+25855579+28195142	11	2.3e-19	0.0387304	0.0811		0.63	0.601-0.658	OR	3.26	1.69-6.26	3.26	1.69-6.26	3.12	1.94-5.02	3.12	1.94-5.02	2.68	1.92-3.74	2.68	1.92-3.74	2.63	2.03-3.41	2.63	2.03-3.41	2.33	1.88-2.88	2.33	1.88-2.88	1.45	1.01-2.1	0.0448	1.9	1.34-2.69	0.000338	3.41	2.46-4.72	1.55e-13	True	False	False	False	Both	389	3881	GRCh37/hg19	P<=5e-06					2020-06-08
prsweb-phecode193-ukbb-saige-hrc-x193-p-5e-06-mgi-20200608	prsweb-phecode193-ukbb-saige-hrc-x193-p-5e-06-mgi-20200608	PRSWEB_PHECODE193_UKBB-SAIGE-HRC-X193_P_5e-06_MGI_20200608	P_5e-06	PRSWEB_PHECODE193_UKBB-SAIGE-HRC-X193_P_5e-06_MGI_20200608	193	Thyroid cancer	Binary	ICD9 and ICD10 based PheWAS codes	MGI	Michigan Genomics Initiative	Fixed threshold (5e-06)	UKB GWAS (PheCode)	UKB_GWAS	https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761	11	0.00033	0.00733806	0.0825		0.54	0.509-0.568	OR	1.89	0.854-4.19	1.89	0.854-4.19	2	1.14-3.49	2	1.14-3.49	1.59	1.07-2.37	1.59	1.07-2.37	1.33	0.974-1.82	1.33	0.974-1.82	1.34	1.07-1.68	1.34	1.07-1.68	1.34	0.971-1.85	0.0746	1.57	1.15-2.14	0.0048	1.73	1.27-2.35	0.000479	True	False	False	False	Both	389	3881	GRCh37/hg19	P<=5e-06					2020-06-08
prsweb-phecode193-c3-thyroid-gland-p-5e-07-mgi-20200608	prsweb-phecode193-c3-thyroid-gland-p-5e-07-mgi-20200608	PRSWEB_PHECODE193_C3-THYROID-GLAND_P_5e-07_MGI_20200608	P_5e-07	PRSWEB_PHECODE193_C3-THYROID-GLAND_P_5e-07_MGI_20200608	193	Malignant neoplasm of thyroid gland	Binary	GWAS round 2: Results shared 1st August 2018. Imputed genotypes from HRC plus UK10K & 1000 Genomes reference panels as released by UK Biobank in March 2018.	MGI	Michigan Genomics Initiative	Fixed threshold (5e-07)	UKB GWAS (FINNGEN)	UKB_GWAS	https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761	5	6.1e-05	0.00966258	0.0825		0.549	0.518-0.58	OR	1.39	0.562-3.44	1.39	0.562-3.44	1.34	0.695-2.58	1.34	0.695-2.58	1.54	1.03-2.3	1.54	1.03-2.3	1.65	1.23-2.21	1.65	1.23-2.21	1.47	1.18-1.84	1.47	1.18-1.84	1.05	0.753-1.46	0.777	1.56	1.15-2.12	0.00459	1.76	1.31-2.38	0.000214	True	False	False	False	Both	389	3881	GRCh37/hg19	P<=5e-07					2020-06-08
prsweb-phecode193-gwas-catalog-r2019-05-03-x193-p-5e-07-mgi-20200608	prsweb-phecode193-gwas-catalog-r2019-05-03-x193-p-5e-07-mgi-20200608	PRSWEB_PHECODE193_GWAS-Catalog-r2019-05-03-X193_P_5e-07_MGI_20200608	P_5e-07	PRSWEB_PHECODE193_GWAS-Catalog-r2019-05-03-X193_P_5e-07_MGI_20200608	193	Thyroid cancer	Binary	19 unique SNPs	MGI	Michigan Genomics Initiative	Fixed threshold (5e-07)	GWAS Catalog (2019-05-03)	19198613;22267200;23894154;25855579;28195142	https://www.ncbi.nlm.nih.gov/pubmed/?term=19198613+22267200+23894154+25855579+28195142	11	2.3e-19	0.0387304	0.0811		0.63	0.601-0.658	OR	3.26	1.69-6.26	3.26	1.69-6.26	3.12	1.94-5.02	3.12	1.94-5.02	2.68	1.92-3.74	2.68	1.92-3.74	2.63	2.03-3.41	2.63	2.03-3.41	2.33	1.88-2.88	2.33	1.88-2.88	1.45	1.01-2.1	0.0448	1.9	1.34-2.69	0.000338	3.41	2.46-4.72	1.55e-13	True	False	False	False	Both	389	3881	GRCh37/hg19	P<=5e-07					2020-06-08
prsweb-phecode193-gwas-catalog-r2019-05-03-x193-p-5e-09-mgi-20200608	prsweb-phecode193-gwas-catalog-r2019-05-03-x193-p-5e-09-mgi-20200608	PRSWEB_PHECODE193_GWAS-Catalog-r2019-05-03-X193_P_5e-09_MGI_20200608	P_5e-09	PRSWEB_PHECODE193_GWAS-Catalog-r2019-05-03-X193_P_5e-09_MGI_20200608	193	Thyroid cancer	Binary	19 unique SNPs	MGI	Michigan Genomics Initiative	Fixed threshold (5e-09)	GWAS Catalog (2019-05-03)	19198613;22267200;23894154;25855579;28195142	https://www.ncbi.nlm.nih.gov/pubmed/?term=19198613+22267200+23894154+25855579+28195142	9	1.4e-17	0.0386535	0.0812		0.62	0.591-0.649	OR	4.04	2.21-7.39	4.04	2.21-7.39	3.83	2.46-5.98	3.83	2.46-5.98	2.74	1.97-3.82	2.74	1.97-3.82	2.48	1.91-3.22	2.48	1.91-3.22	2.1	1.69-2.6	2.1	1.69-2.6	1.35	0.94-1.93	0.105	1.87	1.33-2.62	0.000297	2.94	2.14-4.05	3.12e-11	True	False	False	False	Both	389	3881	GRCh37/hg19	P<=5e-09					2020-06-08
prsweb-phecode193-gwas-catalog-r2019-05-03-x193-p-5e-08-mgi-20200608	prsweb-phecode193-gwas-catalog-r2019-05-03-x193-p-5e-08-mgi-20200608	PRSWEB_PHECODE193_GWAS-Catalog-r2019-05-03-X193_P_5e-08_MGI_20200608	P_5e-08	PRSWEB_PHECODE193_GWAS-Catalog-r2019-05-03-X193_P_5e-08_MGI_20200608	193	Thyroid cancer	Binary	19 unique SNPs	MGI	Michigan Genomics Initiative	GWAS Hits	GWAS Catalog (2019-05-03)	19198613;22267200;23894154;25855579;28195142	https://www.ncbi.nlm.nih.gov/pubmed/?term=19198613+22267200+23894154+25855579+28195142	10	2e-18	0.0374073	0.0811		0.626	0.597-0.655	OR	3.53	1.87-6.66	3.53	1.87-6.66	2.7	1.64-4.46	2.7	1.64-4.46	2.81	2.02-3.9	2.81	2.02-3.9	2.48	1.91-3.22	2.48	1.91-3.22	2.24	1.81-2.77	2.24	1.81-2.77	1.46	1.02-2.11	0.0412	1.96	1.39-2.78	0.000142	3.34	2.41-4.63	4.81e-13	True	False	False	True	Both	389	3881	GRCh37/hg19	P<=5e-08	https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000630/ScoringFiles/	https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000630/ScoringFiles/	/larsf/prsweb-data/cancerprsweb/releases/cancerprsweb_20200608/phewas/PRSWEB_PHECODE193_GWAS-Catalog-r2019-05-03-X193_P_5e-08_MGI_20200608/all.tsv	/larsf/prsweb-data/cancerprsweb/releases/cancerprsweb_20200608/phewas/PRSWEB_PHECODE193_GWAS-Catalog-r2019-05-03-X193_P_5e-08_MGI_20200608/exclusion.tsv	2020-06-08
prsweb-phecode193-20001-1065-pt-mgi-20200608	prsweb-phecode193-20001-1065-pt-mgi-20200608	PRSWEB_PHECODE193_20001-1065_PT_MGI_20200608	P&T	PRSWEB_PHECODE193_20001-1065_PT_MGI_20200608	193	Cancer code, self-reported: thyroid cancer	Binary	GWAS round 2: Results shared 1st August 2018. Imputed genotypes from HRC plus UK10K & 1000 Genomes reference panels as released by UK Biobank in March 2018.	MGI	Michigan Genomics Initiative	P&T	UKB GWAS (PHESANT)	UKB_GWAS	https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761	8	0.0041	0.00738545	0.0826		0.529	0.496-0.559	OR	2.44	1.18-5.02	2.44	1.18-5.02	1.74	0.964-3.13	1.74	0.964-3.13	1.71	1.16-2.52	1.71	1.16-2.52	1.49	1.1-2.01	1.49	1.1-2.01	1.32	1.05-1.66	1.32	1.05-1.66	1.1	0.801-1.5	0.566	1.28	0.943-1.73	0.114	1.48	1.1-1.99	0.00902	True	False	False	True	Both	389	3881	GRCh37/hg19	P<=3.98e-06	https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000626/ScoringFiles/	https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000626/ScoringFiles/	/larsf/prsweb-data/cancerprsweb/releases/cancerprsweb_20200608/phewas/PRSWEB_PHECODE193_20001-1065_PT_MGI_20200608/all.tsv	/larsf/prsweb-data/cancerprsweb/releases/cancerprsweb_20200608/phewas/PRSWEB_PHECODE193_20001-1065_PT_MGI_20200608/exclusion.tsv	2020-06-08
prsweb-phecode193-c3-thyroid-gland-pt-mgi-20200608	prsweb-phecode193-c3-thyroid-gland-pt-mgi-20200608	PRSWEB_PHECODE193_C3-THYROID-GLAND_PT_MGI_20200608	P&T	PRSWEB_PHECODE193_C3-THYROID-GLAND_PT_MGI_20200608	193	Malignant neoplasm of thyroid gland	Binary	GWAS round 2: Results shared 1st August 2018. Imputed genotypes from HRC plus UK10K & 1000 Genomes reference panels as released by UK Biobank in March 2018.	MGI	Michigan Genomics Initiative	P&T	UKB GWAS (FINNGEN)	UKB_GWAS	https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761	11	3.4e-06	0.0171123	0.0824		0.56	0.53-0.59	OR	2.42	1.17-4.98	2.42	1.17-4.98	1.73	0.96-3.12	1.73	0.96-3.12	1.48	0.987-2.23	1.48	0.987-2.23	1.58	1.18-2.13	1.58	1.18-2.13	1.39	1.11-1.74	1.39	1.11-1.74	1.33	0.959-1.85	0.0873	1.69	1.23-2.31	0.00107	1.85	1.36-2.52	9.79e-05	True	False	False	True	Both	389	3881	GRCh37/hg19	P<=5e-06	https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000627/ScoringFiles/	https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000627/ScoringFiles/	/larsf/prsweb-data/cancerprsweb/releases/cancerprsweb_20200608/phewas/PRSWEB_PHECODE193_C3-THYROID-GLAND_PT_MGI_20200608/all.tsv	/larsf/prsweb-data/cancerprsweb/releases/cancerprsweb_20200608/phewas/PRSWEB_PHECODE193_C3-THYROID-GLAND_PT_MGI_20200608/exclusion.tsv	2020-06-08
prsweb-phecode193-c73-pt-mgi-20200608	prsweb-phecode193-c73-pt-mgi-20200608	PRSWEB_PHECODE193_C73_PT_MGI_20200608	P&T	PRSWEB_PHECODE193_C73_PT_MGI_20200608	193	Diagnoses - main ICD10: C73 Malignant neoplasm of thyroid gland	Binary	GWAS round 2: Results shared 1st August 2018. Imputed genotypes from HRC plus UK10K & 1000 Genomes reference panels as released by UK Biobank in March 2018.	MGI	Michigan Genomics Initiative	P&T	UKB GWAS (ICD10)	UKB_GWAS	https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761	8	0.027	0.00999042	0.0827		0.52	0.488-0.55	OR	2.15	1.01-4.59	2.15	1.01-4.59	1.73	0.956-3.12	1.73	0.956-3.12	1.77	1.2-2.59	1.77	1.2-2.59	1.49	1.1-2.01	1.49	1.1-2.01	1.18	0.938-1.49	1.18	0.938-1.49	1.05	0.77-1.42	0.769	1.22	0.906-1.64	0.189	1.29	0.961-1.74	0.0902	True	False	False	True	Both	389	3881	GRCh37/hg19	P<=1.26e-06	https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000629/ScoringFiles/	https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000629/ScoringFiles/	/larsf/prsweb-data/cancerprsweb/releases/cancerprsweb_20200608/phewas/PRSWEB_PHECODE193_C73_PT_MGI_20200608/all.tsv	/larsf/prsweb-data/cancerprsweb/releases/cancerprsweb_20200608/phewas/PRSWEB_PHECODE193_C73_PT_MGI_20200608/exclusion.tsv	2020-06-08
prsweb-phecode193-gwas-catalog-r2019-05-03-x193-pt-mgi-20200608	prsweb-phecode193-gwas-catalog-r2019-05-03-x193-pt-mgi-20200608	PRSWEB_PHECODE193_GWAS-Catalog-r2019-05-03-X193_PT_MGI_20200608	P&T	PRSWEB_PHECODE193_GWAS-Catalog-r2019-05-03-X193_PT_MGI_20200608	193	Thyroid cancer	Binary	19 unique SNPs	MGI	Michigan Genomics Initiative	P&T	GWAS Catalog (2019-05-03)	19198613;22267200;23894154;25855579;28195142	https://www.ncbi.nlm.nih.gov/pubmed/?term=19198613+22267200+23894154+25855579+28195142	8	2.9e-17	0.0417495	0.0812		0.618	0.587-0.647	OR	5.14	2.94-8.99	5.14	2.94-8.99	3.54	2.25-5.59	3.54	2.25-5.59	3.06	2.22-4.22	3.06	2.22-4.22	2.44	1.87-3.17	2.44	1.87-3.17	2.07	1.67-2.57	2.07	1.67-2.57	1.37	0.956-1.96	0.0869	1.89	1.34-2.64	0.000241	2.9	2.1-3.98	6.48e-11	True	False	False	True	Both	389	3881	GRCh37/hg19	P<=3.16e-10	https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000632/ScoringFiles/	https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000632/ScoringFiles/	/larsf/prsweb-data/cancerprsweb/releases/cancerprsweb_20200608/phewas/PRSWEB_PHECODE193_GWAS-Catalog-r2019-05-03-X193_PT_MGI_20200608/all.tsv	/larsf/prsweb-data/cancerprsweb/releases/cancerprsweb_20200608/phewas/PRSWEB_PHECODE193_GWAS-Catalog-r2019-05-03-X193_PT_MGI_20200608/exclusion.tsv	2020-06-08
prsweb-phecode193-ukbb-saige-hrc-x193-pt-mgi-20200608	prsweb-phecode193-ukbb-saige-hrc-x193-pt-mgi-20200608	PRSWEB_PHECODE193_UKBB-SAIGE-HRC-X193_PT_MGI_20200608	P&T	PRSWEB_PHECODE193_UKBB-SAIGE-HRC-X193_PT_MGI_20200608	193	Thyroid cancer	Binary	ICD9 and ICD10 based PheWAS codes	MGI	Michigan Genomics Initiative	P&T	UKB GWAS (PheCode)	UKB_GWAS	https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761	5	2.7e-08	0.0157305	0.0822		0.569	0.538-0.598	OR	1.65	0.708-3.83	1.65	0.708-3.83	1.6	0.871-2.94	1.6	0.871-2.94	1.77	1.21-2.6	1.77	1.21-2.6	1.91	1.44-2.53	1.91	1.44-2.53	1.58	1.26-1.97	1.58	1.26-1.97	1.3	0.924-1.83	0.132	1.69	1.23-2.34	0.00142	2.09	1.53-2.86	4.17e-06	True	False	False	True	Both	389	3881	GRCh37/hg19	P<=2e-06	https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000635/ScoringFiles/	https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000635/ScoringFiles/	/larsf/prsweb-data/cancerprsweb/releases/cancerprsweb_20200608/phewas/PRSWEB_PHECODE193_UKBB-SAIGE-HRC-X193_PT_MGI_20200608/all.tsv	/larsf/prsweb-data/cancerprsweb/releases/cancerprsweb_20200608/phewas/PRSWEB_PHECODE193_UKBB-SAIGE-HRC-X193_PT_MGI_20200608/exclusion.tsv	2020-06-08
prsweb-phecode193-20001-1065-prs-cs-mgi-20200608	prsweb-phecode193-20001-1065-prs-cs-mgi-20200608	PRSWEB_PHECODE193_20001-1065_PRS-CS_MGI_20200608	PRS-CS	PRSWEB_PHECODE193_20001-1065_PRS-CS_MGI_20200608	193	Cancer code, self-reported: thyroid cancer	Binary	GWAS round 2: Results shared 1st August 2018. Imputed genotypes from HRC plus UK10K & 1000 Genomes reference panels as released by UK Biobank in March 2018.	MGI	Michigan Genomics Initiative	PRS-CS	UKB GWAS (PHESANT)	UKB_GWAS	https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761	1042118	0.11	0.000177902	0.0827		0.526	0.497-0.558	OR	2.16	1.01-4.6	2.16	1.01-4.6	1.6	0.869-2.93	1.6	0.869-2.93	1.43	0.943-2.16	1.43	0.943-2.16	1.09	0.782-1.53	1.09	0.782-1.53	1.23	0.975-1.54	1.23	0.975-1.54	1.09	0.807-1.47	0.574	1.04	0.769-1.41	0.789	1.29	0.966-1.73	0.0838	False	False	False	False	Both	389	3881	GRCh37/hg19	auto					2020-06-08
prsweb-phecode193-c3-thyroid-gland-prs-cs-mgi-20200608	prsweb-phecode193-c3-thyroid-gland-prs-cs-mgi-20200608	PRSWEB_PHECODE193_C3-THYROID-GLAND_PRS-CS_MGI_20200608	PRS-CS	PRSWEB_PHECODE193_C3-THYROID-GLAND_PRS-CS_MGI_20200608	193	Malignant neoplasm of thyroid gland	Binary	GWAS round 2: Results shared 1st August 2018. Imputed genotypes from HRC plus UK10K & 1000 Genomes reference panels as released by UK Biobank in March 2018.	MGI	Michigan Genomics Initiative	PRS-CS	UKB GWAS (FINNGEN)	UKB_GWAS	https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761	1054932	0.24	0.000454599	0.0828		0.52	0.49-0.549	OR	1.65	0.708-3.83	1.65	0.708-3.83	1.08	0.526-2.21	1.08	0.526-2.21	1.32	0.859-2.02	1.32	0.859-2.02	1.15	0.83-1.6	1.15	0.83-1.6	0.999	0.785-1.27	0.999	0.785-1.27	1.27	0.932-1.72	0.131	1.46	1.08-1.96	0.014	1.24	0.913-1.7	0.166	False	False	False	False	Both	389	3881	GRCh37/hg19	auto					2020-06-08
prsweb-phecode193-c73-prs-cs-mgi-20200608	prsweb-phecode193-c73-prs-cs-mgi-20200608	PRSWEB_PHECODE193_C73_PRS-CS_MGI_20200608	PRS-CS	PRSWEB_PHECODE193_C73_PRS-CS_MGI_20200608	193	Diagnoses - main ICD10: C73 Malignant neoplasm of thyroid gland	Binary	GWAS round 2: Results shared 1st August 2018. Imputed genotypes from HRC plus UK10K & 1000 Genomes reference panels as released by UK Biobank in March 2018.	MGI	Michigan Genomics Initiative	PRS-CS	UKB GWAS (ICD10)	UKB_GWAS	https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761	1027375	0.13	0.000138231	0.0828		0.527	0.498-0.558	OR	0.377	0.0725-1.96	0.377	0.0725-1.96	0.695	0.29-1.67	0.695	0.29-1.67	1.48	0.987-2.23	1.48	0.987-2.23	1.42	1.05-1.93	1.42	1.05-1.93	1.21	0.965-1.53	1.21	0.965-1.53	1.31	0.964-1.77	0.0846	1.16	0.851-1.58	0.346	1.41	1.04-1.89	0.0255	False	False	False	False	Both	389	3881	GRCh37/hg19	auto					2020-06-08
prsweb-phecode193-ukbb-saige-hrc-x193-prs-cs-mgi-20200608	prsweb-phecode193-ukbb-saige-hrc-x193-prs-cs-mgi-20200608	PRSWEB_PHECODE193_UKBB-SAIGE-HRC-X193_PRS-CS_MGI_20200608	PRS-CS	PRSWEB_PHECODE193_UKBB-SAIGE-HRC-X193_PRS-CS_MGI_20200608	193	Thyroid cancer	Binary	ICD9 and ICD10 based PheWAS codes	MGI	Michigan Genomics Initiative	PRS-CS	UKB GWAS (PheCode)	UKB_GWAS	https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761	1119238	0.035	0.000208927	0.0827		0.535	0.504-0.567	OR	1.39	0.562-3.45	1.39	0.562-3.45	1.34	0.696-2.58	1.34	0.696-2.58	1.32	0.86-2.02	1.32	0.86-2.02	1.27	0.926-1.75	1.27	0.926-1.75	1.21	0.964-1.53	1.21	0.964-1.53	1.06	0.779-1.45	0.707	1.24	0.917-1.67	0.163	1.34	0.994-1.79	0.0549	True	False	False	True	Both	389	3881	GRCh37/hg19	auto	https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000634/ScoringFiles/	https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000634/ScoringFiles/	/larsf/prsweb-data/cancerprsweb/releases/cancerprsweb_20200608/phewas/PRSWEB_PHECODE193_UKBB-SAIGE-HRC-X193_PRS-CS_MGI_20200608/all.tsv	/larsf/prsweb-data/cancerprsweb/releases/cancerprsweb_20200608/phewas/PRSWEB_PHECODE193_UKBB-SAIGE-HRC-X193_PRS-CS_MGI_20200608/exclusion.tsv	2020-06-08
prsweb-phecode193-20001-1065-lassosum-mgi-20200608	prsweb-phecode193-20001-1065-lassosum-mgi-20200608	PRSWEB_PHECODE193_20001-1065_LASSOSUM_MGI_20200608	Lassosum	PRSWEB_PHECODE193_20001-1065_LASSOSUM_MGI_20200608	193	Cancer code, self-reported: thyroid cancer	Binary	GWAS round 2: Results shared 1st August 2018. Imputed genotypes from HRC plus UK10K & 1000 Genomes reference panels as released by UK Biobank in March 2018.	MGI	Michigan Genomics Initiative	lassosum	UKB GWAS (PHESANT)	UKB_GWAS	https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761	1515	0.14	0.00230821	0.0828		0.518	0.488-0.549	OR	1.39	0.559-3.43	1.39	0.559-3.43	1.6	0.871-2.94	1.6	0.871-2.94	1.04	0.654-1.67	1.04	0.654-1.67	1.01	0.715-1.42	1.01	0.715-1.42	1.2	0.952-1.51	1.2	0.952-1.51	1.19	0.876-1.61	0.268	1.17	0.865-1.59	0.305	1.33	0.985-1.78	0.0629	False	False	False	False	Both	389	3881	GRCh37/hg19	s=1;Lambda=0.1					2020-06-08
prsweb-phecode193-c3-thyroid-gland-lassosum-mgi-20200608	prsweb-phecode193-c3-thyroid-gland-lassosum-mgi-20200608	PRSWEB_PHECODE193_C3-THYROID-GLAND_LASSOSUM_MGI_20200608	Lassosum	PRSWEB_PHECODE193_C3-THYROID-GLAND_LASSOSUM_MGI_20200608	193	Malignant neoplasm of thyroid gland	Binary	GWAS round 2: Results shared 1st August 2018. Imputed genotypes from HRC plus UK10K & 1000 Genomes reference panels as released by UK Biobank in March 2018.	MGI	Michigan Genomics Initiative	lassosum	UKB GWAS (FINNGEN)	UKB_GWAS	https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761	656	1.7e-06	0.0110299	0.0823		0.565	0.535-0.595	OR	1.91	0.861-4.22	1.91	0.861-4.22	1.74	0.964-3.13	1.74	0.964-3.13	1.6	1.08-2.38	1.6	1.08-2.38	1.62	1.2-2.17	1.62	1.2-2.17	1.42	1.14-1.78	1.42	1.14-1.78	1.22	0.878-1.7	0.236	1.64	1.2-2.24	0.00196	1.83	1.35-2.49	0.00011	True	False	False	True	Both	389	3881	GRCh37/hg19	s=1;Lambda=0.1	https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000628/ScoringFiles/	https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000628/ScoringFiles/	/larsf/prsweb-data/cancerprsweb/releases/cancerprsweb_20200608/phewas/PRSWEB_PHECODE193_C3-THYROID-GLAND_LASSOSUM_MGI_20200608/all.tsv	/larsf/prsweb-data/cancerprsweb/releases/cancerprsweb_20200608/phewas/PRSWEB_PHECODE193_C3-THYROID-GLAND_LASSOSUM_MGI_20200608/exclusion.tsv	2020-06-08
prsweb-phecode193-c73-lassosum-mgi-20200608	prsweb-phecode193-c73-lassosum-mgi-20200608	PRSWEB_PHECODE193_C73_LASSOSUM_MGI_20200608	Lassosum	PRSWEB_PHECODE193_C73_LASSOSUM_MGI_20200608	193	Diagnoses - main ICD10: C73 Malignant neoplasm of thyroid gland	Binary	GWAS round 2: Results shared 1st August 2018. Imputed genotypes from HRC plus UK10K & 1000 Genomes reference panels as released by UK Biobank in March 2018.	MGI	Michigan Genomics Initiative	lassosum	UKB GWAS (ICD10)	UKB_GWAS	https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761	3017	0.12	0.00378028	0.0828		0.523	0.491-0.556	OR	1.14	0.422-3.05	1.14	0.422-3.05	1.08	0.527-2.21	1.08	0.527-2.21	1.15	0.736-1.81	1.15	0.736-1.81	1.04	0.737-1.46	1.04	0.737-1.46	1.23	0.975-1.54	1.23	0.975-1.54	1.05	0.771-1.42	0.767	1.15	0.85-1.55	0.368	1.33	0.994-1.79	0.0545	False	False	False	False	Both	389	3881	GRCh37/hg19	s=0.9;Lambda=0.1					2020-06-08
prsweb-phecode193-ukbb-saige-hrc-x193-lassosum-mgi-20200608	prsweb-phecode193-ukbb-saige-hrc-x193-lassosum-mgi-20200608	PRSWEB_PHECODE193_UKBB-SAIGE-HRC-X193_LASSOSUM_MGI_20200608	Lassosum	PRSWEB_PHECODE193_UKBB-SAIGE-HRC-X193_LASSOSUM_MGI_20200608	193	Thyroid cancer	Binary	ICD9 and ICD10 based PheWAS codes	MGI	Michigan Genomics Initiative	lassosum	UKB GWAS (PheCode)	UKB_GWAS	https://www.ncbi.nlm.nih.gov/pubmed/?term=30104761	954	1.3e-10	0.0135905	0.0819		0.578	0.548-0.607	OR	3.21	1.67-6.15	3.21	1.67-6.15	2.96	1.82-4.79	2.96	1.82-4.79	2.12	1.48-3.04	2.12	1.48-3.04	2.08	1.58-2.74	2.08	1.58-2.74	1.63	1.31-2.03	1.63	1.31-2.03	1.44	1.03-2.02	0.0352	1.75	1.27-2.43	0.000741	2.27	1.66-3.1	3.17e-07	True	False	False	True	Both	389	3881	GRCh37/hg19	s=1;Lambda=0.1	https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000636/ScoringFiles/	https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000636/ScoringFiles/	/larsf/prsweb-data/cancerprsweb/releases/cancerprsweb_20200608/phewas/PRSWEB_PHECODE193_UKBB-SAIGE-HRC-X193_LASSOSUM_MGI_20200608/all.tsv	/larsf/prsweb-data/cancerprsweb/releases/cancerprsweb_20200608/phewas/PRSWEB_PHECODE193_UKBB-SAIGE-HRC-X193_LASSOSUM_MGI_20200608/exclusion.tsv	2020-06-08