phewas_code phewas_string sex MatchedCases MatchedControls groupnum group color N N_Q1 N_Q2 N_Q3 N_Q4 PRS_BETA PRS_SEBETA PRS_P PRS_LOG10P PRS_OR PRS_CI1 PRS_CI2 Q1Q2_BETA Q1Q2_SEBETA Q1Q2_P Q1Q2_LOG10P Q1Q2_OR Q1Q2_CI1 Q1Q2_CI2 Q1Q3_BETA Q1Q3_SEBETA Q1Q3_P Q1Q3_LOG10P Q1Q3_OR Q1Q3_CI1 Q1Q3_CI2 Q1Q4_BETA Q1Q4_SEBETA Q1Q4_P Q1Q4_LOG10P Q1Q4_OR Q1Q4_CI1 Q1Q4_CI2 predictor 008 Intestinal infection Both 1401 22216 1 infectious diseases blue 22216, 1401 5554, 360 5554, 332 5554, 367 5554, 342 -0.0103 0.0276 0.709 0.1495 0.99 0.938 1.04 -0.0814 0.0784 0.299 0.5244 0.922 0.791 1.07 0.0264 0.0766 0.731 0.1363 1.03 0.884 1.19 -0.054 0.0781 0.489 0.3107 0.947 0.813 1.1 PRS_PLINK_0.001 008.5 Bacterial enteritis Both 372 6809 1 infectious diseases blue 6809, 372 1703, 100 1702, 85 1702, 99 1702, 88 -0.0311 0.0537 0.563 0.2494 0.969 0.872 1.08 -0.161 0.151 0.286 0.5443 0.852 0.634 1.14 -0.0145 0.145 0.921 0.03587 0.986 0.741 1.31 -0.15 0.149 0.315 0.5019 0.861 0.642 1.15 PRS_PLINK_0.001 008.52 Intestinal infection due to C. difficile Both 60 1596 1 infectious diseases blue 1596, 60 399, 19 399, 10 399, 16 399, 15 -0.105 0.13 0.42 0.3772 0.9 0.697 1.16 -0.676 0.378 0.0737 1.132 0.509 0.243 1.07 -0.16 0.333 0.63 0.2006 0.852 0.444 1.64 -0.24 0.339 0.479 0.3198 0.786 0.405 1.53 PRS_PLINK_0.001 008.6 Viral Enteritis Both 110 2166 1 infectious diseases blue 2166, 110 542, 29 541, 24 541, 39 542, 18 -0.0586 0.0966 0.544 0.2644 0.943 0.78 1.14 -0.199 0.276 0.471 0.3273 0.82 0.477 1.41 0.291 0.247 0.238 0.6239 1.34 0.825 2.17 -0.472 0.297 0.111 0.9529 0.624 0.349 1.12 PRS_PLINK_0.001 008.7 Intestinal infection due to protozoa Both 13 136 1 infectious diseases blue 136, 13 34, 3 34, 2 34, 5 34, 3 -0.00326 0.283 0.991 0.003999 0.997 0.572 1.74 -0.118 0.819 0.886 0.05281 0.889 0.178 4.43 0.775 0.752 0.303 0.519 2.17 0.497 9.47 -0.425 0.833 0.61 0.2148 0.654 0.128 3.35 PRS_PLINK_0.001 010 Tuberculosis Both 24 417 1 infectious diseases blue 417, 24 105, 5 104, 8 104, 3 104, 8 -0.0525 0.193 0.785 0.1049 0.949 0.65 1.38 0.415 0.527 0.43 0.3662 1.51 0.54 4.25 -0.511 0.639 0.424 0.3725 0.6 0.171 2.1 0.397 0.532 0.456 0.3409 1.49 0.524 4.22 PRS_PLINK_0.001 038 Septicemia Both 418 10517 1 infectious diseases blue 10517, 418 2630, 118 2629, 113 2629, 81 2629, 106 -0.0409 0.05 0.413 0.3841 0.96 0.87 1.06 -0.0387 0.134 0.772 0.1124 0.962 0.74 1.25 -0.366 0.146 0.0121 1.919 0.693 0.521 0.923 -0.113 0.136 0.406 0.3914 0.893 0.684 1.17 PRS_PLINK_0.001 038.1 Gram negative septicemia Both 91 2095 1 infectious diseases blue 2095, 91 524, 32 524, 19 523, 12 524, 28 -0.051 0.107 0.635 0.1969 0.95 0.77 1.17 -0.54 0.288 0.0607 1.217 0.583 0.332 1.02 -0.971 0.33 0.00325 2.488 0.379 0.198 0.723 -0.172 0.263 0.514 0.2892 0.842 0.503 1.41 PRS_PLINK_0.001 038.2 Gram positive septicemia Both 45 1255 1 infectious diseases blue 1255, 45 314, 13 314, 15 313, 9 314, 8 -0.18 0.145 0.216 0.6653 0.836 0.629 1.11 0.125 0.368 0.733 0.1347 1.13 0.551 2.33 -0.296 0.412 0.472 0.326 0.744 0.332 1.67 -0.392 0.428 0.36 0.4435 0.676 0.292 1.56 PRS_PLINK_0.001 041 Bacterial infection NOS Both 1737 30511 1 infectious diseases blue 30511, 1737 7628, 441 7628, 411 7627, 430 7628, 455 -0.00362 0.0248 0.884 0.05357 0.996 0.949 1.05 -0.0705 0.0704 0.317 0.4993 0.932 0.812 1.07 -0.0168 0.0698 0.81 0.0917 0.983 0.858 1.13 0.0429 0.069 0.534 0.2724 1.04 0.912 1.2 PRS_PLINK_0.001 041.1 Staphylococcus infections Both 411 8086 1 infectious diseases blue 8086, 411 2022, 93 2021, 112 2021, 95 2022, 111 0.00957 0.0503 0.849 0.07102 1.01 0.915 1.11 0.183 0.143 0.199 0.7001 1.2 0.908 1.59 0.0196 0.148 0.895 0.04806 1.02 0.762 1.36 0.201 0.144 0.162 0.7915 1.22 0.923 1.62 PRS_PLINK_0.001 041.2 Streptococcus infection Both 271 4233 1 infectious diseases blue 4233, 271 1059, 64 1058, 61 1058, 63 1058, 83 0.0542 0.0628 0.388 0.4112 1.06 0.933 1.19 -0.0247 0.183 0.893 0.04936 0.976 0.682 1.4 -0.00168 0.181 0.993 0.00323 0.998 0.7 1.42 0.32 0.172 0.0622 1.206 1.38 0.984 1.93 PRS_PLINK_0.001 041.4 E. coli Both 348 6821 1 infectious diseases blue 6821, 348 1706, 87 1705, 77 1705, 87 1705, 97 0.0171 0.0557 0.759 0.1199 1.02 0.912 1.13 -0.119 0.159 0.455 0.3422 0.888 0.651 1.21 0.0408 0.155 0.792 0.1013 1.04 0.769 1.41 0.13 0.151 0.392 0.4069 1.14 0.846 1.53 PRS_PLINK_0.001 053 Herpes zoster Both 57 985 1 infectious diseases blue 985, 57 247, 10 246, 14 246, 17 246, 16 0.166 0.134 0.215 0.6671 1.18 0.908 1.54 0.331 0.397 0.405 0.3929 1.39 0.64 3.03 0.53 0.388 0.171 0.7661 1.7 0.795 3.63 0.493 0.393 0.21 0.6776 1.64 0.757 3.54 PRS_PLINK_0.001 053.1 Herpes zoster with nervous system complications Both 15 245 1 infectious diseases blue 245, 15 62, 3 61, 2 61, 5 61, 5 0.289 0.247 0.242 0.6154 1.34 0.822 2.17 -0.447 0.752 0.553 0.2576 0.64 0.147 2.79 0.658 0.668 0.325 0.4883 1.93 0.521 7.16 0.607 0.666 0.362 0.4411 1.83 0.498 6.76 PRS_PLINK_0.001 054 Herpes simplex Both 34 523 1 infectious diseases blue 523, 34 131, 4 131, 9 130, 8 131, 13 0.509 0.187 0.00635 2.197 1.66 1.15 2.4 0.937 0.557 0.0925 1.034 2.55 0.857 7.61 0.58 0.571 0.31 0.5089 1.79 0.583 5.47 1.02 0.528 0.0524 1.28 2.78 0.989 7.83 PRS_PLINK_0.001 070 Viral hepatitis Both 103 1464 1 infectious diseases blue 1464, 103 366, 28 366, 32 366, 26 366, 17 -0.245 0.103 0.017 1.769 0.783 0.64 0.957 0.113 0.265 0.669 0.1746 1.12 0.666 1.88 -0.0864 0.278 0.756 0.1217 0.917 0.532 1.58 -0.437 0.309 0.157 0.804 0.646 0.352 1.18 PRS_PLINK_0.001 070.1 Viral hepatitis A Both 18 179 1 infectious diseases blue 179, 18 45, 2 45, 6 44, 5 45, 5 0.141 0.232 0.543 0.2652 1.15 0.731 1.81 1.28 0.804 0.112 0.9519 3.59 0.743 17.4 1.34 0.925 0.147 0.8324 3.83 0.624 23.5 0.931 0.761 0.221 0.6552 2.54 0.571 11.3 PRS_PLINK_0.001 070.2 Viral hepatitis B Both 22 346 1 infectious diseases blue 346, 22 87, 6 86, 8 86, 5 87, 3 -0.273 0.208 0.19 0.7222 0.761 0.506 1.14 0.279 0.515 0.588 0.2305 1.32 0.481 3.63 -0.253 0.571 0.657 0.1822 0.776 0.253 2.38 -0.755 0.63 0.231 0.6358 0.47 0.137 1.62 PRS_PLINK_0.001 070.3 Viral hepatitis C Both 30 666 1 infectious diseases blue 666, 30 167, 13 166, 9 166, 6 167, 2 -0.593 0.185 0.00132 2.878 0.552 0.385 0.794 -0.371 0.426 0.383 0.4162 0.69 0.299 1.59 -0.68 0.467 0.145 0.8393 0.506 0.203 1.26 -1.62 0.644 0.0116 1.935 0.197 0.0558 0.696 PRS_PLINK_0.001 070.4 Chronic hepatitis Both 41 718 1 infectious diseases blue 718, 41 180, 10 179, 10 179, 6 180, 15 0.0746 0.163 0.648 0.1885 1.08 0.782 1.48 -0.0153 0.429 0.971 0.01256 0.985 0.425 2.28 -0.457 0.486 0.348 0.4586 0.633 0.244 1.64 0.414 0.406 0.307 0.5123 1.51 0.683 3.35 PRS_PLINK_0.001 070.9 Hepatitis NOS Both 60 1102 1 infectious diseases blue 1102, 60 276, 18 275, 9 275, 15 276, 18 0.0385 0.13 0.767 0.1154 1.04 0.806 1.34 -0.638 0.392 0.103 0.9862 0.528 0.245 1.14 -0.1 0.347 0.773 0.112 0.905 0.459 1.78 0.035 0.334 0.916 0.03791 1.04 0.538 1.99 PRS_PLINK_0.001 071 Human immunodeficiency virus [HIV] disease Both 43 325 1 infectious diseases blue 325, 43 82, 6 81, 6 81, 13 81, 18 0.474 0.172 0.00572 2.243 1.61 1.15 2.25 0.678 0.492 0.168 0.7743 1.97 0.751 5.17 PRS_PLINK_0.001 071.1 HIV infection, symptomatic Both 33 251 1 infectious diseases blue 251, 33 63, 6 63, 5 62, 9 63, 13 0.333 0.2 0.0963 1.016 1.4 0.942 2.07 0.244 0.535 0.649 0.1878 1.28 0.447 3.64 0.632 0.516 0.22 0.6569 1.88 0.685 5.17 PRS_PLINK_0.001 078 Viral warts & HPV Both 214 2609 1 infectious diseases blue 2609, 214 653, 51 652, 56 652, 57 652, 50 -0.0249 0.0723 0.731 0.1363 0.975 0.847 1.12 0.0944 0.199 0.635 0.1973 1.1 0.744 1.62 0.115 0.199 0.562 0.2499 1.12 0.76 1.66 -0.00582 0.205 0.977 0.009935 0.994 0.665 1.49 PRS_PLINK_0.001 079 Viral infection Both 541 7180 1 infectious diseases blue 7180, 541 1795, 151 1795, 129 1795, 130 1795, 131 -0.0757 0.0446 0.0901 1.045 0.927 0.849 1.01 -0.158 0.124 0.202 0.6938 0.854 0.67 1.09 -0.139 0.124 0.263 0.5794 0.87 0.682 1.11 -0.134 0.124 0.281 0.5521 0.875 0.686 1.12 PRS_PLINK_0.001 079.1 Varicella infection Both 15 164 1 infectious diseases blue 164, 15 41, 6 41, 1 41, 3 41, 5 0.0118 0.245 0.962 0.01704 1.01 0.626 1.64 -2.07 1.05 0.0485 1.314 0.127 0.0162 0.986 -0.191 0.708 0.787 0.1041 0.826 0.206 3.31 -0.498 0.691 0.471 0.3271 0.608 0.157 2.35 PRS_PLINK_0.001 080 Postoperative infection Both 743 11444 1 infectious diseases blue 11444, 743 2861, 176 2861, 180 2861, 199 2861, 188 0.0246 0.0382 0.52 0.2839 1.02 0.951 1.1 0.0269 0.109 0.805 0.09413 1.03 0.83 1.27 0.132 0.107 0.217 0.663 1.14 0.925 1.41 0.0676 0.108 0.533 0.2736 1.07 0.865 1.32 PRS_PLINK_0.001 081 Infection/inflammation of internal prosthetic device; implant; and graft Both 351 6132 1 infectious diseases blue 6132, 351 1533, 85 1533, 96 1533, 92 1533, 78 -0.0429 0.0547 0.433 0.3639 0.958 0.861 1.07 0.134 0.152 0.38 0.42 1.14 0.848 1.54 0.0908 0.154 0.556 0.2549 1.1 0.809 1.48 -0.0613 0.161 0.703 0.1533 0.941 0.686 1.29 PRS_PLINK_0.001 090 Sexually transmitted infections (not HIV or hepatitis) Both 11 166 1 infectious diseases blue 166, 11 42, 0 41, 3 41, 6 42, 2 0.169 0.263 0.519 0.2845 1.18 0.708 1.98 1.79 1.14 0.116 0.9357 5.96 0.644 55.3 2.62 1.23 0.0328 1.485 13.8 1.24 153 1.58 1.27 0.215 0.6673 4.84 0.4 58.5 PRS_PLINK_0.001 110 Dermatophytosis / Dermatomycosis Both 66 730 1 infectious diseases blue 730, 66 183, 22 182, 16 182, 13 183, 15 -0.157 0.129 0.224 0.65 0.854 0.663 1.1 -0.255 0.338 0.45 0.3464 0.775 0.399 1.5 -0.424 0.355 0.232 0.6341 0.654 0.326 1.31 -0.298 0.348 0.391 0.4075 0.742 0.375 1.47 PRS_PLINK_0.001 110.1 Dermatophytosis Both 65 701 1 infectious diseases blue 701, 65 176, 22 175, 15 175, 14 175, 14 -0.183 0.132 0.164 0.7851 0.832 0.643 1.08 -0.331 0.344 0.336 0.4738 0.718 0.366 1.41 -0.339 0.35 0.332 0.4784 0.713 0.359 1.41 -0.375 0.355 0.291 0.5367 0.687 0.343 1.38 PRS_PLINK_0.001 110.11 Dermatophytosis of nail Both 19 205 1 infectious diseases blue 205, 19 52, 3 51, 5 51, 7 51, 4 -0.0671 0.217 0.758 0.1206 0.935 0.611 1.43 0.402 0.69 0.561 0.2514 1.49 0.386 5.78 0.549 0.652 0.4 0.3976 1.73 0.482 6.22 0.032 0.711 0.964 0.01586 1.03 0.256 4.16 PRS_PLINK_0.001 110.12 Althete's foot Both 37 349 1 infectious diseases blue 349, 37 88, 13 87, 9 87, 8 87, 7 -0.136 0.181 0.452 0.3452 0.873 0.612 1.24 -0.3 0.449 0.503 0.2983 0.74 0.307 1.78 -0.353 0.462 0.445 0.3518 0.702 0.284 1.74 -0.569 0.486 0.242 0.6162 0.566 0.218 1.47 PRS_PLINK_0.001 112 Candidiasis Both 280 5335 1 infectious diseases blue 5335, 280 1334, 74 1334, 71 1333, 65 1334, 70 0.0315 0.0618 0.61 0.2144 1.03 0.914 1.16 -0.0626 0.169 0.711 0.1479 0.939 0.674 1.31 -0.124 0.173 0.474 0.3245 0.884 0.63 1.24 -0.082 0.171 0.63 0.2003 0.921 0.66 1.29 PRS_PLINK_0.001 117 Mycoses Both 43 663 1 infectious diseases blue 663, 43 165, 8 166, 10 165, 13 166, 12 0.176 0.157 0.261 0.5839 1.19 0.877 1.62 0.286 0.47 0.543 0.2652 1.33 0.53 3.34 0.396 0.438 0.366 0.4364 1.49 0.629 3.51 0.397 0.44 0.367 0.4353 1.49 0.628 3.52 PRS_PLINK_0.001 117.4 Aspergillosis Both 29 402 1 infectious diseases blue 402, 29 101, 7 100, 8 100, 7 101, 7 -0.116 0.194 0.549 0.2604 0.89 0.609 1.3 0.27 0.518 0.602 0.2201 1.31 0.474 3.62 -0.09 0.521 0.863 0.06411 0.914 0.329 2.54 -0.0199 0.508 0.969 0.01377 0.98 0.362 2.65 PRS_PLINK_0.001 130 Spirochetal infection Both 19 202 1 infectious diseases blue 202, 19 51, 2 50, 5 50, 8 51, 4 0.319 0.234 0.174 0.7606 1.38 0.869 2.18 1.33 0.852 0.118 0.9288 3.79 0.714 20.1 1.13 0.766 0.141 0.8508 3.09 0.688 13.9 0.553 0.766 0.47 0.3276 1.74 0.387 7.8 PRS_PLINK_0.001 133 Arthropod-borne diseases Both 20 172 1 infectious diseases blue 172, 20 43, 5 43, 5 43, 2 43, 8 0.0519 0.228 0.82 0.08607 1.05 0.673 1.65 0.0469 0.633 0.941 0.02642 1.05 0.303 3.63 -0.833 0.73 0.254 0.5951 0.435 0.104 1.82 0.214 0.614 0.727 0.1382 1.24 0.372 4.13 PRS_PLINK_0.001 134 Helminthiases Both 35 310 1 infectious diseases blue 310, 35 78, 7 77, 14 77, 12 78, 2 -0.14 0.181 0.439 0.3577 0.869 0.61 1.24 0.675 0.47 0.151 0.8218 1.96 0.782 4.93 0.711 0.492 0.148 0.829 2.04 0.777 5.34 -0.946 0.699 0.176 0.7548 0.388 0.0986 1.53 PRS_PLINK_0.001 134.1 Intestinal helminthiases Both 30 255 1 infectious diseases blue 255, 30 64, 5 64, 13 63, 11 64, 1 -0.163 0.2 0.413 0.384 0.849 0.574 1.26 0.959 0.53 0.0702 1.154 2.61 0.924 7.36 0.859 0.537 0.109 0.9606 2.36 0.824 6.77 -1.12 0.874 0.199 0.7001 0.326 0.0588 1.81 PRS_PLINK_0.001 136 Other infectious and parasitic diseases Both 34 490 1 infectious diseases blue 490, 34 123, 12 122, 5 122, 9 123, 8 -0.159 0.175 0.365 0.4383 0.853 0.605 1.2 -0.968 0.515 0.0604 1.219 0.38 0.138 1.04 -0.431 0.451 0.34 0.4687 0.65 0.269 1.57 -0.301 0.448 0.501 0.3 0.74 0.307 1.78 PRS_PLINK_0.001 145 Cancer of mouth Both 96 1703 2 neoplasms darkcyan 1703, 96 426, 17 426, 26 425, 26 426, 27 0.106 0.101 0.294 0.5309 1.11 0.912 1.35 0.403 0.307 0.189 0.7245 1.5 0.82 2.73 0.444 0.309 0.15 0.8229 1.56 0.851 2.85 0.496 0.309 0.108 0.9656 1.64 0.897 3.01 PRS_PLINK_0.001 145.2 Cancer of tongue Both 45 821 2 neoplasms darkcyan 821, 45 206, 10 205, 12 205, 14 205, 9 0.00904 0.144 0.95 0.02222 1.01 0.76 1.34 0.128 0.414 0.757 0.1211 1.14 0.505 2.56 0.338 0.404 0.403 0.3945 1.4 0.635 3.1 -0.135 0.438 0.758 0.1205 0.874 0.37 2.06 PRS_PLINK_0.001 145.3 Cancer of major salivary glands Both 20 274 2 neoplasms darkcyan 274, 20 69, 4 68, 6 68, 5 69, 5 0.00327 0.203 0.987 0.005618 1 0.674 1.49 0.339 0.603 0.574 0.2413 1.4 0.431 4.58 0.202 0.631 0.748 0.1259 1.22 0.356 4.22 0.697 0.708 0.324 0.489 2.01 0.502 8.04 PRS_PLINK_0.001 145.5 Cancer of the mouth floor Both 3 132 2 neoplasms darkcyan 132, 3 33, 0 33, 1 33, 1 33, 1 0.301 0.431 0.486 0.3138 1.35 0.58 3.14 0.905 1.31 0.488 0.3116 2.47 0.191 31.9 0.803 1.2 0.503 0.2987 2.23 0.213 23.3 0.611 1.15 0.594 0.2262 1.84 0.195 17.4 PRS_PLINK_0.001 149 Cancer of larynx, pharynx, nasal cavities Both 94 1630 2 neoplasms darkcyan 1630, 94 408, 15 407, 27 407, 23 408, 29 0.27 0.105 0.0102 1.991 1.31 1.07 1.61 0.596 0.317 0.0598 1.223 1.82 0.976 3.38 0.377 0.326 0.247 0.6069 1.46 0.77 2.76 0.634 0.315 0.0442 1.355 1.89 1.02 3.5 PRS_PLINK_0.001 149.1 Cancer of oropharynx Both 38 681 2 neoplasms darkcyan 681, 38 171, 5 170, 16 170, 10 170, 7 0.173 0.164 0.291 0.5354 1.19 0.862 1.64 1.1 0.478 0.021 1.678 3.02 1.18 7.7 0.636 0.497 0.201 0.6977 1.89 0.713 5 0.251 0.528 0.635 0.1972 1.28 0.456 3.62 PRS_PLINK_0.001 149.4 Cancer of larynx Both 36 655 2 neoplasms darkcyan 655, 36 164, 6 164, 9 163, 7 164, 14 0.39 0.159 0.0144 1.843 1.48 1.08 2.02 0.382 0.486 0.432 0.3648 1.47 0.565 3.8 0.109 0.517 0.834 0.07896 1.11 0.404 3.07 0.836 0.462 0.0704 1.153 2.31 0.933 5.71 PRS_PLINK_0.001 149.9 Cancer of of nasal cavities Both 13 129 2 neoplasms darkcyan 129, 13 33, 1 32, 4 32, 2 32, 6 0.468 0.304 0.124 0.9076 1.6 0.88 2.9 1.17 0.925 0.208 0.6825 3.21 0.523 19.7 1.14 0.975 0.244 0.6128 3.11 0.461 21 1.43 0.979 0.144 0.8429 4.18 0.615 28.5 PRS_PLINK_0.001 150 Cancer of esophagus Both 52 1879 2 neoplasms darkcyan 1879, 52 470, 10 470, 14 469, 10 470, 18 0.193 0.138 0.163 0.7888 1.21 0.925 1.59 0.38 0.39 0.331 0.4807 1.46 0.68 3.14 0.00871 0.418 0.983 0.007285 1.01 0.445 2.29 0.565 0.377 0.133 0.8748 1.76 0.841 3.68 PRS_PLINK_0.001 151 Cancer of stomach Both 40 1341 2 neoplasms darkcyan 1341, 40 336, 10 335, 9 335, 10 335, 11 -0.00709 0.155 0.964 0.01609 0.993 0.732 1.35 -0.13 0.429 0.761 0.1187 0.878 0.379 2.03 0.0138 0.426 0.974 0.01139 1.01 0.44 2.33 0.037 0.417 0.929 0.03188 1.04 0.458 2.35 PRS_PLINK_0.001 153 Colorectal cancer Both 797 11333 2 neoplasms darkcyan 11333, 797 2834, 190 2833, 187 2833, 208 2833, 212 0.0572 0.0368 0.12 0.9191 1.06 0.985 1.14 -0.0141 0.106 0.894 0.04844 0.986 0.801 1.21 0.111 0.104 0.284 0.546 1.12 0.912 1.37 0.123 0.103 0.236 0.6273 1.13 0.923 1.38 PRS_PLINK_0.001 153.2 Colon cancer Both 505 7596 2 neoplasms darkcyan 7596, 505 1899, 120 1899, 119 1899, 129 1899, 137 0.0618 0.0463 0.181 0.7414 1.06 0.972 1.16 -0.0171 0.133 0.898 0.04694 0.983 0.758 1.28 0.0861 0.131 0.51 0.2925 1.09 0.844 1.41 0.143 0.129 0.268 0.5725 1.15 0.896 1.49 PRS_PLINK_0.001 153.3 Malignant neoplasm of rectum, rectosigmoid junction, and anus Both 379 5421 2 neoplasms darkcyan 5421, 379 1356, 88 1355, 85 1355, 97 1355, 109 0.113 0.0534 0.0344 1.463 1.12 1.01 1.24 -0.025 0.156 0.872 0.05927 0.975 0.719 1.32 0.105 0.151 0.489 0.3105 1.11 0.825 1.49 0.22 0.148 0.138 0.8613 1.25 0.932 1.67 PRS_PLINK_0.001 155 Cancer of liver and intrahepatic bile duct Both 16 943 2 neoplasms darkcyan 943, 16 236, 2 236, 10 235, 1 236, 3 -0.247 0.222 0.266 0.5758 0.781 0.505 1.21 1.4 0.638 0.0279 1.555 4.07 1.16 14.2 -0.384 0.79 0.627 0.203 0.681 0.145 3.2 0.326 0.688 0.635 0.1969 1.39 0.36 5.34 PRS_PLINK_0.001 155.1 Malignant neoplasm of liver, primary Both 7 392 2 neoplasms darkcyan 392, 7 98, 1 98, 3 98, 1 98, 2 -0.41 0.286 0.152 0.8171 0.664 0.379 1.16 0.882 0.814 0.279 0.555 2.42 0.49 11.9 0.0677 0.869 0.938 0.02783 1.07 0.195 5.87 0.374 0.82 0.649 0.1881 1.45 0.291 7.25 PRS_PLINK_0.001 157 Pancreatic cancer Both 21 1584 2 neoplasms darkcyan 1584, 21 396, 4 396, 6 396, 3 396, 8 0.204 0.201 0.309 0.5098 1.23 0.828 1.82 0.352 0.551 0.523 0.2817 1.42 0.483 4.19 -0.165 0.621 0.791 0.1018 0.848 0.251 2.87 0.745 0.544 0.171 0.7674 2.11 0.725 6.12 PRS_PLINK_0.001 158 Neoplasm of unspecified nature of digestive system Both 191 2741 2 neoplasms darkcyan 2741, 191 686, 39 685, 49 685, 55 685, 48 0.069 0.074 0.351 0.4546 1.07 0.927 1.24 0.221 0.217 0.31 0.509 1.25 0.815 1.91 0.349 0.214 0.102 0.99 1.42 0.933 2.16 0.206 0.22 0.35 0.4554 1.23 0.798 1.89 PRS_PLINK_0.001 159 Malignant neoplasm of other and ill-defined sites within the digestive organs and peritoneum Both 994 13798 2 neoplasms darkcyan 13798, 994 3450, 220 3449, 253 3449, 261 3450, 260 0.0558 0.033 0.0905 1.043 1.06 0.991 1.13 0.137 0.0951 0.15 0.8244 1.15 0.952 1.38 0.18 0.0946 0.0569 1.245 1.2 0.995 1.44 0.17 0.0949 0.0738 1.132 1.18 0.984 1.43 PRS_PLINK_0.001 159.2 Malignant neoplasm of small intestine, including duodenum Both 27 509 2 neoplasms darkcyan 509, 27 128, 6 127, 5 127, 8 127, 8 0.157 0.183 0.392 0.4067 1.17 0.817 1.68 -0.153 0.565 0.786 0.1043 0.858 0.284 2.6 0.382 0.517 0.46 0.3371 1.46 0.532 4.03 0.566 0.533 0.288 0.541 1.76 0.62 5.01 PRS_PLINK_0.001 159.3 Malignant neoplasm of gallbladder and extrahepatic bile ducts Both 10 485 2 neoplasms darkcyan 485, 10 122, 1 121, 4 121, 2 121, 3 0.528 0.302 0.0803 1.095 1.7 0.938 3.06 1.03 0.795 0.196 0.7088 2.8 0.589 13.3 0.748 0.874 0.392 0.4068 2.11 0.381 11.7 1.52 0.861 0.0775 1.111 4.57 0.846 24.7 PRS_PLINK_0.001 159.4 Malignant neoplasm of retroperitoneum and peritoneum Both 17 445 2 neoplasms darkcyan 445, 17 112, 6 111, 4 111, 6 111, 1 -0.373 0.218 0.0867 1.062 0.689 0.449 1.06 -0.33 0.609 0.589 0.2302 0.719 0.218 2.37 -0.014 0.549 0.98 0.008916 0.986 0.336 2.89 -1.34 0.793 0.0908 1.042 0.262 0.0553 1.24 PRS_PLINK_0.001 164 Cancer of intrathoracic organs Both 13 148 2 neoplasms darkcyan 148, 13 37, 2 37, 5 37, 1 37, 5 0.268 0.285 0.347 0.4596 1.31 0.748 2.28 0.723 0.799 0.365 0.4372 2.06 0.43 9.87 -0.659 1.01 0.514 0.2892 0.517 0.0714 3.74 0.623 0.861 0.47 0.3283 1.86 0.345 10.1 PRS_PLINK_0.001 165 Cancer within the respiratory system Both 143 6643 2 neoplasms darkcyan 6643, 143 1661, 29 1661, 34 1660, 41 1661, 39 0.112 0.0837 0.182 0.7398 1.12 0.949 1.32 0.134 0.248 0.59 0.2294 1.14 0.703 1.86 0.318 0.239 0.183 0.7369 1.37 0.86 2.2 0.275 0.242 0.256 0.5913 1.32 0.819 2.12 PRS_PLINK_0.001 165.1 Cancer of bronchus; lung Both 94 5211 2 neoplasms darkcyan 5211, 94 1303, 17 1303, 23 1302, 28 1303, 26 0.139 0.103 0.178 0.7485 1.15 0.939 1.41 0.239 0.308 0.437 0.3597 1.27 0.695 2.32 0.464 0.298 0.12 0.922 1.59 0.887 2.85 0.4 0.302 0.186 0.7297 1.49 0.824 2.7 PRS_PLINK_0.001 170 Cancer of bone and connective tissue Both 71 1101 2 neoplasms darkcyan 1101, 71 276, 17 275, 16 275, 27 275, 11 0.0233 0.12 0.846 0.07251 1.02 0.809 1.3 -0.0847 0.345 0.806 0.09354 0.919 0.467 1.81 0.37 0.313 0.238 0.6242 1.45 0.784 2.67 -0.521 0.382 0.173 0.7631 0.594 0.281 1.26 PRS_PLINK_0.001 170.1 Bone cancer Both 19 367 2 neoplasms darkcyan 367, 19 92, 2 92, 5 91, 8 92, 4 0.27 0.23 0.24 0.619 1.31 0.835 2.06 0.806 0.709 0.256 0.592 2.24 0.557 8.99 1.18 0.668 0.0787 1.104 3.24 0.874 12 0.891 0.794 0.262 0.5823 2.44 0.514 11.6 PRS_PLINK_0.001 170.2 Cancer of connective tissue Both 54 800 2 neoplasms darkcyan 800, 54 200, 15 200, 14 200, 17 200, 8 0.00737 0.138 0.958 0.01886 1.01 0.768 1.32 -0.0508 0.369 0.89 0.05037 0.95 0.461 1.96 0.0787 0.355 0.825 0.08375 1.08 0.539 2.17 -0.62 0.425 0.145 0.8388 0.538 0.234 1.24 PRS_PLINK_0.001 172 Skin cancer Both 3324 33309 2 neoplasms darkcyan 33309, 3324 8327, 835 8327, 870 8327, 805 8327, 814 -0.00909 0.0183 0.619 0.2082 0.991 0.956 1.03 0.0376 0.0509 0.46 0.3375 1.04 0.94 1.15 -0.0364 0.0518 0.483 0.3164 0.964 0.871 1.07 -0.0305 0.0519 0.557 0.2544 0.97 0.876 1.07 PRS_PLINK_0.001 172.1 Melanomas of skin, dx or hx Both 649 6783 2 neoplasms darkcyan 6783, 649 1695, 161 1696, 177 1695, 156 1696, 155 -0.0375 0.0414 0.364 0.439 0.963 0.888 1.04 0.0805 0.114 0.481 0.3183 1.08 0.867 1.36 -0.0382 0.118 0.745 0.1277 0.962 0.764 1.21 -0.0766 0.118 0.516 0.2873 0.926 0.735 1.17 PRS_PLINK_0.001 172.11 Melanomas of skin Both 657 6873 2 neoplasms darkcyan 6873, 657 1718, 162 1718, 181 1718, 160 1718, 154 -0.0401 0.0412 0.33 0.4816 0.961 0.886 1.04 0.0968 0.113 0.393 0.4056 1.1 0.882 1.38 -0.0176 0.117 0.88 0.05557 0.983 0.781 1.24 -0.088 0.118 0.456 0.3413 0.916 0.727 1.15 PRS_PLINK_0.001 172.2 Other non-epithelial cancer of skin Both 2730 26979 2 neoplasms darkcyan 26979, 2730 6745, 674 6745, 725 6744, 645 6745, 686 0.00179 0.0202 0.929 0.03183 1 0.963 1.04 0.0734 0.0562 0.192 0.717 1.08 0.964 1.2 -0.0415 0.0578 0.472 0.326 0.959 0.857 1.07 0.0193 0.0571 0.736 0.1334 1.02 0.912 1.14 PRS_PLINK_0.001 172.3 Carcinoma in situ of skin Both 159 1549 2 neoplasms darkcyan 1549, 159 388, 52 387, 32 387, 45 387, 30 -0.106 0.0828 0.201 0.6968 0.9 0.765 1.06 -0.462 0.235 0.0492 1.308 0.63 0.397 0.998 -0.12 0.214 0.575 0.2403 0.887 0.583 1.35 -0.543 0.239 0.0229 1.641 0.581 0.364 0.927 PRS_PLINK_0.001 173 Neoplasm of uncertain behavior of skin Both 43 482 2 neoplasms darkcyan 482, 43 121, 12 120, 11 120, 6 121, 14 0.0275 0.166 0.869 0.06117 1.03 0.742 1.42 0.0104 0.425 0.981 0.008518 1.01 0.439 2.33 -0.705 0.488 0.148 0.8292 0.494 0.19 1.28 0.169 0.407 0.679 0.1683 1.18 0.533 2.63 PRS_PLINK_0.001 174 Breast cancer Both 2926 32892 2 neoplasms darkcyan 32892, 2926 8222, 740 8223, 717 8223, 723 8223, 746 0.0119 0.0195 0.541 0.2672 1.01 0.974 1.05 -0.0292 0.0547 0.593 0.227 0.971 0.873 1.08 -0.0194 0.0547 0.723 0.141 0.981 0.881 1.09 0.00985 0.0544 0.856 0.06738 1.01 0.908 1.12 PRS_PLINK_0.001 174.1 Breast cancer [female] Female 2884 32349 2 neoplasms darkcyan 32349, 2884 8087, 735 8087, 705 8087, 713 8087, 731 0.00674 0.0196 0.732 0.1358 1.01 0.969 1.05 -0.0392 0.055 0.476 0.3222 0.962 0.863 1.07 -0.0264 0.055 0.632 0.1996 0.974 0.874 1.08 -0.00304 0.0548 0.956 0.01969 0.997 0.896 1.11 PRS_PLINK_0.001 174.11 Malignant neoplasm of female breast Female 2680 30434 2 neoplasms darkcyan 30434, 2680 7608, 679 7608, 665 7608, 657 7609, 679 0.00988 0.0204 0.628 0.2023 1.01 0.97 1.05 -0.0182 0.0569 0.749 0.1257 0.982 0.878 1.1 -0.0284 0.0572 0.619 0.2083 0.972 0.869 1.09 0.00327 0.0569 0.954 0.0204 1 0.897 1.12 PRS_PLINK_0.001 174.3 Neoplasm of uncertain behavior of breast Both 33 296 2 neoplasms darkcyan 296, 33 74, 9 74, 5 74, 11 74, 8 0.101 0.199 0.61 0.2143 1.11 0.75 1.63 -0.44 0.557 0.429 0.3673 0.644 0.216 1.92 -0.0124 0.485 0.98 0.008986 0.988 0.382 2.55 PRS_PLINK_0.001 175 Acquired absence of breast Female 479 6140 2 neoplasms darkcyan 6140, 479 1534, 117 1535, 122 1535, 104 1535, 136 0.042 0.0479 0.38 0.4197 1.04 0.949 1.15 0.0345 0.134 0.797 0.09858 1.04 0.796 1.35 -0.108 0.139 0.439 0.3575 0.898 0.684 1.18 0.132 0.131 0.313 0.5044 1.14 0.883 1.48 PRS_PLINK_0.001 180 Cervical cancer and dysplasia Female 500 5974 2 neoplasms darkcyan 5974, 500 1494, 121 1493, 134 1493, 135 1494, 110 -0.0314 0.0467 0.501 0.3 0.969 0.884 1.06 0.103 0.13 0.428 0.3684 1.11 0.859 1.43 0.109 0.13 0.403 0.3946 1.11 0.864 1.44 -0.0957 0.137 0.484 0.3156 0.909 0.695 1.19 PRS_PLINK_0.001 180.1 Cervical cancer Female 52 691 2 neoplasms darkcyan 691, 52 173, 11 173, 20 172, 10 173, 11 -0.164 0.14 0.239 0.6214 0.848 0.645 1.12 0.508 0.379 0.18 0.7439 1.66 0.791 3.49 -0.17 0.442 0.701 0.1545 0.844 0.355 2 -0.0648 0.424 0.879 0.05624 0.937 0.409 2.15 PRS_PLINK_0.001 180.3 Cervical intraepithelial neoplasia [CIN] [Cervical dysplasia] Female 477 5696 2 neoplasms darkcyan 5696, 477 1424, 117 1424, 123 1424, 134 1424, 103 -0.0272 0.0477 0.569 0.2449 0.973 0.886 1.07 0.0497 0.134 0.71 0.1486 1.05 0.808 1.37 0.126 0.132 0.338 0.4705 1.13 0.876 1.47 -0.123 0.14 0.38 0.4207 0.884 0.672 1.16 PRS_PLINK_0.001 182 Malignant neoplasm of uterus Female 265 3167 2 neoplasms darkcyan 3167, 265 792, 75 792, 69 791, 60 792, 61 -0.0817 0.0641 0.203 0.6934 0.922 0.813 1.04 -0.0809 0.173 0.64 0.1939 0.922 0.657 1.29 -0.202 0.18 0.261 0.5833 0.817 0.575 1.16 -0.191 0.179 0.286 0.5429 0.827 0.582 1.17 PRS_PLINK_0.001 184 Cancer of other female genital organs Female 231 3453 2 neoplasms darkcyan 3453, 231 864, 73 863, 51 863, 55 863, 52 -0.148 0.0692 0.0326 1.487 0.862 0.753 0.988 -0.368 0.187 0.0494 1.306 0.692 0.479 0.999 -0.324 0.185 0.0804 1.095 0.723 0.503 1.04 -0.32 0.187 0.0866 1.062 0.726 0.503 1.05 PRS_PLINK_0.001 184.1 Malignant neoplasm of ovary and other uterine adnexa Female 147 2381 2 neoplasms darkcyan 2381, 147 596, 51 595, 37 595, 29 595, 30 -0.201 0.0861 0.0196 1.708 0.818 0.691 0.968 -0.341 0.221 0.123 0.9118 0.711 0.461 1.1 -0.643 0.24 0.00741 2.13 0.526 0.328 0.842 -0.53 0.237 0.025 1.603 0.588 0.37 0.935 PRS_PLINK_0.001 184.11 Malignant neoplasm of ovary Female 139 2338 2 neoplasms darkcyan 2338, 139 585, 49 584, 34 584, 26 585, 30 -0.197 0.0885 0.026 1.586 0.821 0.69 0.977 -0.393 0.228 0.0847 1.072 0.675 0.431 1.06 -0.689 0.249 0.00569 2.245 0.502 0.308 0.818 -0.485 0.239 0.0424 1.373 0.616 0.386 0.983 PRS_PLINK_0.001 184.2 Cancer of other female genital organs (excluding uterus and ovary) Female 62 775 2 neoplasms darkcyan 775, 62 194, 17 194, 10 193, 15 194, 20 -0.022 0.136 0.872 0.05945 0.978 0.749 1.28 -0.437 0.399 0.273 0.5642 0.646 0.296 1.41 -0.0781 0.363 0.83 0.0811 0.925 0.454 1.88 0.144 0.342 0.673 0.1718 1.16 0.591 2.26 PRS_PLINK_0.001 185 Cancer of prostate Male 1388 14781 2 neoplasms darkcyan 14781, 1388 3696, 335 3695, 361 3695, 337 3695, 355 0.00941 0.028 0.737 0.1326 1.01 0.956 1.07 0.0744 0.0793 0.348 0.458 1.08 0.922 1.26 0.0133 0.0806 0.869 0.06085 1.01 0.865 1.19 0.0653 0.0798 0.413 0.3836 1.07 0.913 1.25 PRS_PLINK_0.001 187 Cancer of other male genital organs Male 114 1090 2 neoplasms darkcyan 1090, 114 273, 31 272, 38 272, 25 273, 20 -0.0749 0.0949 0.43 0.3669 0.928 0.77 1.12 0.206 0.253 0.416 0.3806 1.23 0.748 2.02 -0.119 0.28 0.672 0.1727 0.888 0.513 1.54 -0.402 0.297 0.176 0.7556 0.669 0.374 1.2 PRS_PLINK_0.001 187.1 Malignant neoplasm of unspecified male genital organ Male 17 170 2 neoplasms darkcyan 170, 17 43, 4 42, 5 42, 4 43, 4 -0.04 0.272 0.883 0.05404 0.961 0.564 1.64 0.259 0.685 0.706 0.1515 1.3 0.338 4.96 0.642 0.802 0.423 0.3735 1.9 0.395 9.15 -0.482 0.789 0.542 0.2662 0.618 0.132 2.9 PRS_PLINK_0.001 187.2 Malignant neoplasm of testis Male 72 684 2 neoplasms darkcyan 684, 72 171, 22 171, 26 171, 12 171, 12 -0.158 0.121 0.194 0.7123 0.854 0.674 1.08 0.159 0.306 0.604 0.2193 1.17 0.644 2.13 -0.56 0.363 0.123 0.9086 0.571 0.28 1.16 -0.658 0.373 0.0778 1.109 0.518 0.249 1.08 PRS_PLINK_0.001 187.8 Neoplasm of uncertain behavior of male genital organs Male 28 256 2 neoplasms darkcyan 256, 28 64, 6 64, 7 64, 9 64, 6 0.0303 0.188 0.872 0.05943 1.03 0.713 1.49 0.28 0.553 0.613 0.2129 1.32 0.447 3.91 0.43 0.523 0.41 0.3868 1.54 0.552 4.28 0.135 0.585 0.817 0.08775 1.14 0.364 3.6 PRS_PLINK_0.001 189 Cancer of urinary organs (incl. kidney and bladder) Both 740 10347 2 neoplasms darkcyan 10347, 740 2587, 196 2587, 176 2586, 173 2587, 195 -0.0319 0.0379 0.4 0.3981 0.969 0.899 1.04 -0.103 0.107 0.336 0.4732 0.902 0.731 1.11 -0.123 0.108 0.252 0.5994 0.884 0.716 1.09 -0.0011 0.105 0.992 0.00364 0.999 0.813 1.23 PRS_PLINK_0.001 189.1 Cancer of kidney and renal pelvis Both 163 2749 2 neoplasms darkcyan 2749, 163 688, 45 687, 37 687, 42 687, 39 -0.1 0.0797 0.21 0.6788 0.905 0.774 1.06 -0.188 0.225 0.403 0.3944 0.829 0.533 1.29 -0.0539 0.218 0.805 0.09437 0.947 0.618 1.45 -0.138 0.222 0.534 0.2726 0.871 0.563 1.35 PRS_PLINK_0.001 189.11 Malignant neoplasm of kidney, except pelvis Both 154 2658 2 neoplasms darkcyan 2658, 154 665, 42 664, 37 664, 38 665, 37 -0.0926 0.0823 0.26 0.5844 0.912 0.776 1.07 -0.111 0.228 0.627 0.203 0.895 0.572 1.4 -0.0801 0.227 0.724 0.1402 0.923 0.592 1.44 -0.12 0.229 0.6 0.2221 0.887 0.566 1.39 PRS_PLINK_0.001 189.12 Malignant neoplasm of renal pelvis Both 12 144 2 neoplasms darkcyan 144, 12 36, 4 36, 3 36, 3 36, 2 -0.169 0.257 0.51 0.2924 0.844 0.511 1.4 -0.104 0.713 0.884 0.05369 0.901 0.223 3.65 -0.671 0.834 0.421 0.3756 0.511 0.0998 2.62 -0.491 0.741 0.507 0.2947 0.612 0.143 2.61 PRS_PLINK_0.001 189.2 Cancer of bladder Both 432 5924 2 neoplasms darkcyan 5924, 432 1481, 112 1481, 102 1481, 94 1481, 124 0.0103 0.0504 0.838 0.07656 1.01 0.915 1.12 -0.0888 0.141 0.529 0.2768 0.915 0.694 1.21 -0.164 0.144 0.254 0.5957 0.849 0.64 1.12 0.119 0.136 0.381 0.4191 1.13 0.863 1.47 PRS_PLINK_0.001 189.21 Malignant neoplasm of bladder Both 380 5280 2 neoplasms darkcyan 5280, 380 1320, 95 1320, 86 1320, 84 1320, 115 0.0511 0.0539 0.343 0.4647 1.05 0.947 1.17 -0.0898 0.153 0.557 0.2539 0.914 0.677 1.23 -0.116 0.154 0.453 0.3443 0.891 0.659 1.2 0.209 0.144 0.147 0.834 1.23 0.929 1.64 PRS_PLINK_0.001 189.4 Malignant neoplasm of other urinary organs Both 16 346 2 neoplasms darkcyan 346, 16 87, 4 86, 6 86, 3 87, 3 -0.124 0.246 0.616 0.2103 0.884 0.545 1.43 0.0943 0.602 0.876 0.0577 1.1 0.337 3.58 -0.351 0.656 0.593 0.2273 0.704 0.195 2.55 -0.243 0.65 0.708 0.1499 0.784 0.219 2.8 PRS_PLINK_0.001 190 Cancer of eye Both 31 445 2 neoplasms darkcyan 445, 31 112, 12 111, 4 111, 5 111, 10 -0.144 0.178 0.417 0.3802 0.866 0.611 1.23 -0.915 0.556 0.0995 1.002 0.4 0.135 1.19 -0.717 0.535 0.18 0.7446 0.488 0.171 1.39 -0.0241 0.453 0.958 0.01882 0.976 0.402 2.37 PRS_PLINK_0.001 191 Manlignant and unknown neoplasms of brain and nervous system Both 44 1766 2 neoplasms darkcyan 1766, 44 442, 11 441, 15 441, 14 442, 4 -0.226 0.155 0.146 0.8356 0.798 0.588 1.08 0.302 0.383 0.431 0.3655 1.35 0.638 2.87 0.248 0.387 0.521 0.2831 1.28 0.601 2.73 -0.897 0.523 0.0863 1.064 0.408 0.146 1.14 PRS_PLINK_0.001 191.1 Cancer of brain and nervous system Both 22 1455 2 neoplasms darkcyan 1455, 22 364, 7 364, 6 363, 6 364, 3 -0.26 0.202 0.198 0.7034 0.771 0.519 1.15 -0.112 0.497 0.822 0.08512 0.894 0.337 2.37 -0.134 0.507 0.792 0.1013 0.875 0.324 2.36 -0.61 0.592 0.303 0.5189 0.543 0.17 1.73 PRS_PLINK_0.001 191.11 Cancer of brain Both 12 1359 2 neoplasms darkcyan 1359, 12 340, 4 340, 4 339, 3 340, 1 -0.174 0.264 0.51 0.2921 0.841 0.501 1.41 0.112 0.596 0.851 0.07011 1.12 0.348 3.59 -0.204 0.637 0.749 0.1257 0.815 0.234 2.84 -0.714 0.795 0.369 0.4327 0.49 0.103 2.33 PRS_PLINK_0.001 193 Thyroid cancer Both 82 893 2 neoplasms darkcyan 893, 82 224, 19 223, 19 223, 19 223, 25 0.0612 0.113 0.588 0.2309 1.06 0.852 1.33 0.024 0.327 0.941 0.02622 1.02 0.54 1.94 -0.0143 0.33 0.966 0.01522 0.986 0.516 1.88 0.303 0.312 0.332 0.4791 1.35 0.735 2.49 PRS_PLINK_0.001 194 Cancer of other endocrine glands Both 13 239 2 neoplasms darkcyan 239, 13 60, 1 60, 1 59, 6 60, 5 0.755 0.282 0.00737 2.133 2.13 1.22 3.7 -0.132 1.11 0.906 0.04294 0.877 0.0987 7.79 1.5 0.856 0.0791 1.102 4.49 0.84 24.1 1.69 0.905 0.0625 1.204 5.4 0.916 31.8 PRS_PLINK_0.001 195 Cancer, suspected or other Both 3203 42925 2 neoplasms darkcyan 42925, 3203 10732, 761 10731, 849 10731, 728 10731, 865 0.0231 0.0184 0.21 0.6768 1.02 0.987 1.06 0.107 0.0517 0.0391 1.408 1.11 1.01 1.23 -0.0431 0.0537 0.422 0.375 0.958 0.862 1.06 0.124 0.0518 0.0165 1.782 1.13 1.02 1.25 PRS_PLINK_0.001 195.1 Malignant neoplasm, other Both 3040 41323 2 neoplasms darkcyan 41323, 3040 10331, 729 10331, 809 10330, 685 10331, 817 0.0176 0.0189 0.353 0.4525 1.02 0.981 1.06 0.101 0.0529 0.0552 1.258 1.11 0.998 1.23 -0.0614 0.0551 0.265 0.5774 0.94 0.844 1.05 0.109 0.053 0.0391 1.408 1.12 1.01 1.24 PRS_PLINK_0.001 197 Chemotherapy Both 3600 55980 2 neoplasms darkcyan 55980, 3600 13994, 896 13995, 935 13995, 840 13995, 929 -0.00123 0.0172 0.943 0.02541 0.999 0.966 1.03 0.0422 0.0483 0.382 0.4181 1.04 0.949 1.15 -0.0712 0.0496 0.151 0.8199 0.931 0.845 1.03 0.0366 0.0485 0.451 0.3459 1.04 0.943 1.14 PRS_PLINK_0.001 198 Secondary malignant neoplasm Both 998 24532 2 neoplasms darkcyan 24532, 998 6133, 277 6133, 247 6133, 210 6133, 264 -0.0294 0.0323 0.364 0.4392 0.971 0.911 1.03 -0.116 0.0893 0.193 0.7149 0.89 0.747 1.06 -0.27 0.0934 0.00379 2.422 0.763 0.635 0.916 -0.0458 0.0882 0.604 0.219 0.955 0.804 1.14 PRS_PLINK_0.001 198.1 Secondary malignancy of lymph nodes Both 782 13976 2 neoplasms darkcyan 13976, 782 3494, 216 3494, 187 3494, 174 3494, 205 -0.0201 0.0368 0.586 0.2321 0.98 0.912 1.05 -0.153 0.103 0.137 0.8622 0.859 0.702 1.05 -0.211 0.105 0.0443 1.353 0.81 0.66 0.995 -0.047 0.101 0.641 0.193 0.954 0.783 1.16 PRS_PLINK_0.001 198.2 Secondary malignancy of respiratory organs Both 82 5842 2 neoplasms darkcyan 5842, 82 1461, 24 1460, 19 1460, 21 1461, 18 -0.0706 0.108 0.515 0.2883 0.932 0.753 1.15 -0.193 0.296 0.514 0.2888 0.824 0.461 1.47 -0.0816 0.289 0.778 0.1091 0.922 0.523 1.62 -0.244 0.301 0.417 0.3794 0.783 0.434 1.41 PRS_PLINK_0.001 198.3 Secondary malignant neoplasm of digestive systems Both 78 3915 2 neoplasms darkcyan 3915, 78 979, 23 979, 21 978, 17 979, 17 -0.165 0.111 0.14 0.855 0.848 0.682 1.06 -0.109 0.293 0.709 0.1494 0.896 0.505 1.59 -0.33 0.31 0.286 0.5431 0.719 0.392 1.32 -0.332 0.311 0.285 0.5453 0.717 0.39 1.32 PRS_PLINK_0.001 198.4 Secondary malignant neoplasm of liver Both 82 6845 2 neoplasms darkcyan 6845, 82 1712, 17 1711, 24 1711, 16 1711, 25 0.0179 0.11 0.871 0.06013 1.02 0.821 1.26 0.35 0.303 0.249 0.6037 1.42 0.783 2.57 -0.00995 0.331 0.976 0.01055 0.99 0.518 1.89 0.38 0.303 0.209 0.6798 1.46 0.808 2.65 PRS_PLINK_0.001 198.5 Secondary malignancy of brain/spine Both 7 2215 2 neoplasms darkcyan 2215, 7 554, 2 554, 1 553, 3 554, 1 -0.237 0.297 0.424 0.3728 0.789 0.441 1.41 -0.66 0.782 0.399 0.3995 0.517 0.112 2.39 0.282 0.677 0.677 0.1694 1.33 0.352 5 -0.532 0.768 0.489 0.3111 0.588 0.131 2.65 PRS_PLINK_0.001 198.6 Secondary malignancy of bone Both 70 5556 2 neoplasms darkcyan 5556, 70 1389, 20 1389, 21 1389, 10 1389, 19 -0.0564 0.117 0.63 0.2005 0.945 0.751 1.19 0.0588 0.3 0.845 0.07326 1.06 0.589 1.91 -0.67 0.363 0.065 1.187 0.512 0.251 1.04 -0.0491 0.308 0.873 0.05875 0.952 0.52 1.74 PRS_PLINK_0.001 198.7 Secondary malignant neoplasm of skin Both 14 488 2 neoplasms darkcyan 488, 14 122, 4 122, 4 122, 3 122, 3 -0.189 0.241 0.433 0.3637 0.828 0.516 1.33 -0.00136 0.603 0.998 0.00078 0.999 0.307 3.25 -0.203 0.643 0.752 0.124 0.816 0.231 2.88 -0.425 0.672 0.527 0.278 0.654 0.175 2.44 PRS_PLINK_0.001 199 Neoplasm of uncertain behavior Both 228 3676 2 neoplasms darkcyan 3676, 228 919, 56 919, 53 919, 60 919, 59 -0.00228 0.0666 0.973 0.01202 0.998 0.876 1.14 -0.0512 0.195 0.792 0.1011 0.95 0.649 1.39 0.062 0.189 0.743 0.1289 1.06 0.734 1.54 0.0465 0.191 0.808 0.09286 1.05 0.72 1.52 PRS_PLINK_0.001 199.4 Neurofibromatosis Both 9 273 2 neoplasms darkcyan 273, 9 69, 1 68, 1 68, 3 68, 4 0.9 0.335 0.00734 2.135 2.46 1.27 4.75 -1.06 1.23 0.389 0.4097 0.348 0.0314 3.85 0.668 0.86 0.438 0.3588 1.95 0.361 10.5 0.943 0.897 0.293 0.5328 2.57 0.443 14.9 PRS_PLINK_0.001 200 Myeloproliferative disease Both 164 2455 2 neoplasms darkcyan 2455, 164 614, 45 614, 44 613, 36 614, 39 -0.0392 0.0768 0.609 0.2151 0.962 0.827 1.12 -0.0419 0.218 0.847 0.07194 0.959 0.626 1.47 -0.238 0.228 0.297 0.5279 0.788 0.504 1.23 -0.145 0.223 0.514 0.2888 0.865 0.559 1.34 PRS_PLINK_0.001 200.1 Polycythemia vera Both 55 922 2 neoplasms darkcyan 922, 55 231, 14 230, 19 230, 8 231, 14 -0.0816 0.139 0.558 0.2532 0.922 0.702 1.21 0.169 0.356 0.636 0.1965 1.18 0.589 2.38 -0.487 0.431 0.259 0.5868 0.615 0.264 1.43 0.00291 0.373 0.994 0.002708 1 0.483 2.08 PRS_PLINK_0.001 201 Hodgkin's disease Both 49 663 2 neoplasms darkcyan 663, 49 166, 14 166, 14 165, 8 166, 13 -0.0305 0.145 0.834 0.07901 0.97 0.73 1.29 -0.0265 0.378 0.944 0.02504 0.974 0.465 2.04 -0.508 0.432 0.239 0.6212 0.602 0.258 1.4 -0.132 0.387 0.733 0.135 0.876 0.41 1.87 PRS_PLINK_0.001 202 Cancer of other lymphoid, histiocytic tissue Both 445 5644 2 neoplasms darkcyan 5644, 445 1411, 113 1411, 111 1411, 108 1411, 113 -0.0273 0.0495 0.582 0.2353 0.973 0.883 1.07 -0.0186 0.138 0.893 0.04922 0.982 0.749 1.29 -0.0416 0.139 0.765 0.1161 0.959 0.73 1.26 -0.0149 0.138 0.914 0.03906 0.985 0.752 1.29 PRS_PLINK_0.001 202.2 Non-Hodgkins lymphoma Both 353 4425 2 neoplasms darkcyan 4425, 353 1107, 89 1106, 90 1106, 80 1106, 94 -0.0279 0.0557 0.617 0.2098 0.973 0.872 1.08 0.0114 0.154 0.941 0.02631 1.01 0.747 1.37 -0.101 0.159 0.527 0.2779 0.904 0.662 1.24 0.0405 0.153 0.792 0.1015 1.04 0.771 1.41 PRS_PLINK_0.001 202.21 Nodular lymphoma Both 92 900 2 neoplasms darkcyan 900, 92 225, 29 225, 21 225, 13 225, 29 -0.0879 0.105 0.402 0.3954 0.916 0.745 1.13 -0.282 0.295 0.338 0.4707 0.754 0.423 1.34 -0.776 0.335 0.0207 1.684 0.46 0.239 0.888 -0.032 0.277 0.908 0.04191 0.968 0.562 1.67 PRS_PLINK_0.001 202.24 Large cell lymphoma Both 101 1401 2 neoplasms darkcyan 1401, 101 351, 24 350, 28 350, 20 350, 29 -0.0111 0.106 0.917 0.03782 0.989 0.804 1.22 0.158 0.281 0.573 0.2415 1.17 0.675 2.03 -0.227 0.305 0.457 0.34 0.797 0.438 1.45 0.136 0.28 0.627 0.2027 1.15 0.662 1.98 PRS_PLINK_0.001 204 Leukemia Both 261 4161 2 neoplasms darkcyan 4161, 261 1040, 55 1040, 70 1040, 60 1040, 76 0.0934 0.0639 0.144 0.8411 1.1 0.969 1.24 0.24 0.183 0.19 0.7206 1.27 0.888 1.82 0.114 0.19 0.549 0.2607 1.12 0.773 1.62 0.331 0.181 0.0679 1.168 1.39 0.976 1.99 PRS_PLINK_0.001 204.1 Lymphoid leukemia Both 107 1426 2 neoplasms darkcyan 1426, 107 357, 23 356, 27 356, 23 357, 34 0.134 0.103 0.194 0.7121 1.14 0.934 1.4 0.157 0.286 0.583 0.2346 1.17 0.668 2.05 0.0667 0.296 0.822 0.08513 1.07 0.598 1.91 0.426 0.278 0.125 0.9045 1.53 0.889 2.64 PRS_PLINK_0.001 204.11 Lymphoid leukemia, acute Both 9 135 2 neoplasms darkcyan 135, 9 34, 2 34, 1 33, 2 34, 4 0.213 0.269 0.427 0.3698 1.24 0.731 2.1 -0.164 0.961 0.864 0.06341 0.848 0.129 5.58 0.736 1.17 0.531 0.2747 2.09 0.209 20.9 0.368 0.802 0.647 0.1894 1.44 0.3 6.96 PRS_PLINK_0.001 204.12 Lymphoid leukemia, chronic Both 93 1248 2 neoplasms darkcyan 1248, 93 312, 21 312, 23 312, 23 312, 26 0.102 0.11 0.352 0.4539 1.11 0.893 1.37 0.0749 0.304 0.805 0.09403 1.08 0.594 1.96 0.131 0.304 0.668 0.1755 1.14 0.628 2.07 0.215 0.298 0.471 0.327 1.24 0.691 2.22 PRS_PLINK_0.001 204.2 Myeloid leukemia Both 52 1157 2 neoplasms darkcyan 1157, 52 290, 12 289, 13 289, 15 289, 12 -0.0831 0.135 0.537 0.2702 0.92 0.707 1.2 0.0719 0.385 0.852 0.06973 1.07 0.506 2.28 0.172 0.374 0.646 0.1898 1.19 0.57 2.47 0.0622 0.392 0.874 0.05847 1.06 0.493 2.3 PRS_PLINK_0.001 204.21 Myeloid leukemia, acute Both 33 820 2 neoplasms darkcyan 820, 33 205, 9 205, 10 205, 5 205, 9 -0.194 0.162 0.231 0.637 0.823 0.599 1.13 0.0877 0.435 0.84 0.07557 1.09 0.465 2.56 -0.565 0.511 0.269 0.5699 0.569 0.209 1.55 0.0185 0.444 0.967 0.01468 1.02 0.427 2.43 PRS_PLINK_0.001 204.22 Myeloid leukemia, chronic Both 24 348 2 neoplasms darkcyan 348, 24 87, 7 87, 3 87, 10 87, 4 -0.105 0.194 0.589 0.2298 0.9 0.615 1.32 -0.814 0.632 0.198 0.7042 0.443 0.128 1.53 0.378 0.491 0.441 0.3551 1.46 0.557 3.82 -0.417 0.59 0.479 0.3193 0.659 0.207 2.09 PRS_PLINK_0.001 204.4 Multiple myeloma Both 86 1408 2 neoplasms darkcyan 1408, 86 351, 12 352, 26 352, 16 352, 32 0.312 0.111 0.00487 2.312 1.37 1.1 1.7 0.745 0.343 0.0298 1.526 2.11 1.08 4.12 0.438 0.375 0.242 0.6153 1.55 0.743 3.23 0.974 0.333 0.00349 2.457 2.65 1.38 5.09 PRS_PLINK_0.001 208 Benign neoplasm of colon Both 4210 48661 2 neoplasms darkcyan 48661, 4210 12165, 995 12165, 1051 12165, 1042 12165, 1122 0.0397 0.0162 0.0142 1.847 1.04 1.01 1.07 0.0542 0.0461 0.239 0.6214 1.06 0.965 1.16 0.0462 0.0462 0.318 0.4978 1.05 0.957 1.15 0.107 0.0456 0.019 1.722 1.11 1.02 1.22 PRS_PLINK_0.001 210 Benign neoplasm of lip, oral cavity, and pharynx Both 229 2486 2 neoplasms darkcyan 2486, 229 622, 50 621, 62 621, 59 622, 58 -0.0262 0.0678 0.699 0.1554 0.974 0.853 1.11 0.211 0.197 0.284 0.5473 1.23 0.84 1.82 0.168 0.2 0.401 0.3973 1.18 0.8 1.75 0.144 0.2 0.472 0.3262 1.15 0.78 1.71 PRS_PLINK_0.001 211 Benign neoplasm of other parts of digestive system Both 1162 13195 2 neoplasms darkcyan 13195, 1162 3299, 319 3299, 278 3298, 265 3299, 300 -0.031 0.0307 0.313 0.5051 0.969 0.913 1.03 -0.14 0.0856 0.103 0.9876 0.87 0.735 1.03 -0.182 0.0868 0.0363 1.44 0.834 0.703 0.988 -0.0678 0.0844 0.422 0.3749 0.934 0.792 1.1 PRS_PLINK_0.001 212 Benign neoplasm of respiratory and intrathoracic organs Both 60 854 2 neoplasms darkcyan 854, 60 214, 18 213, 11 213, 13 214, 18 0.116 0.134 0.386 0.4139 1.12 0.864 1.46 -0.477 0.38 0.209 0.6796 0.621 0.295 1.31 -0.382 0.367 0.299 0.525 0.683 0.332 1.4 0.0294 0.338 0.931 0.03119 1.03 0.531 2 PRS_PLINK_0.001 213 Benign neoplasm of bone and articular cartilage Both 73 819 2 neoplasms darkcyan 819, 73 205, 22 205, 17 204, 21 205, 13 -0.125 0.118 0.288 0.54 0.882 0.7 1.11 -0.257 0.326 0.43 0.3663 0.773 0.408 1.47 -0.0196 0.316 0.951 0.02201 0.981 0.528 1.82 -0.54 0.355 0.129 0.891 0.583 0.29 1.17 PRS_PLINK_0.001 214 Lipoma Both 1466 15816 2 neoplasms darkcyan 15816, 1466 3954, 365 3954, 387 3954, 356 3954, 358 -0.00557 0.0271 0.837 0.07709 0.994 0.943 1.05 0.0596 0.0763 0.435 0.3618 1.06 0.914 1.23 -0.0141 0.0779 0.857 0.06707 0.986 0.846 1.15 -0.0142 0.078 0.856 0.06757 0.986 0.846 1.15 PRS_PLINK_0.001 214.1 Lipoma of skin and subcutaneous tissue Both 1073 11800 2 neoplasms darkcyan 11800, 1073 2950, 259 2950, 283 2950, 262 2950, 269 -0.000865 0.0316 0.978 0.009581 0.999 0.939 1.06 0.0929 0.0897 0.301 0.5218 1.1 0.92 1.31 0.0242 0.0915 0.791 0.1016 1.02 0.856 1.23 0.0478 0.0911 0.599 0.2223 1.05 0.878 1.25 PRS_PLINK_0.001 215 Other benign neoplasm of connective and other soft tissue Both 265 2775 2 neoplasms darkcyan 2775, 265 694, 68 694, 56 693, 65 694, 76 0.0321 0.0644 0.618 0.209 1.03 0.91 1.17 -0.195 0.187 0.298 0.5258 0.823 0.57 1.19 -0.044 0.181 0.807 0.09294 0.957 0.672 1.36 0.127 0.175 0.47 0.3284 1.14 0.805 1.6 PRS_PLINK_0.001 216 Benign neoplasm of skin Both 1946 19924 2 neoplasms darkcyan 19924, 1946 4980, 496 4981, 477 4981, 467 4981, 506 0.0107 0.0239 0.653 0.1853 1.01 0.965 1.06 -0.0417 0.0672 0.535 0.272 0.959 0.841 1.09 -0.0613 0.0677 0.365 0.4373 0.941 0.824 1.07 0.0244 0.0666 0.714 0.1462 1.02 0.899 1.17 PRS_PLINK_0.001 217 Vascular hamartomas and non-neoplastic nevi Both 127 1555 2 neoplasms darkcyan 1555, 127 388, 28 389, 31 388, 28 389, 40 0.168 0.0946 0.0756 1.121 1.18 0.983 1.42 0.0683 0.264 0.796 0.09919 1.07 0.638 1.8 -0.0248 0.271 0.927 0.03287 0.975 0.573 1.66 0.347 0.253 0.17 0.7696 1.42 0.862 2.32 PRS_PLINK_0.001 217.1 Nevus, non-neoplastic Both 118 1461 2 neoplasms darkcyan 1461, 118 365, 27 365, 31 365, 26 365, 34 0.108 0.097 0.267 0.5742 1.11 0.921 1.35 0.0857 0.268 0.75 0.1252 1.09 0.644 1.84 -0.103 0.28 0.712 0.1474 0.902 0.521 1.56 0.233 0.265 0.38 0.4203 1.26 0.751 2.12 PRS_PLINK_0.001 218 Benign neoplasm of uterus Female 2651 27371 2 neoplasms darkcyan 27371, 2651 6842, 645 6843, 635 6842, 696 6843, 675 0.0299 0.0206 0.145 0.8375 1.03 0.99 1.07 -0.012 0.0585 0.838 0.07693 0.988 0.881 1.11 0.0765 0.0573 0.182 0.7395 1.08 0.965 1.21 0.0561 0.0579 0.333 0.4777 1.06 0.944 1.18 PRS_PLINK_0.001 218.1 Uterine leiomyoma Female 2697 27664 2 neoplasms darkcyan 27664, 2697 6915, 671 6916, 638 6916, 703 6916, 685 0.022 0.0204 0.28 0.5524 1.02 0.982 1.06 -0.0482 0.0578 0.404 0.3934 0.953 0.851 1.07 0.0467 0.0567 0.41 0.3875 1.05 0.938 1.17 0.0268 0.0571 0.639 0.1942 1.03 0.918 1.15 PRS_PLINK_0.001 218.2 Other benign neoplasm of uterus Female 85 979 2 neoplasms darkcyan 979, 85 245, 13 245, 21 244, 27 245, 24 0.165 0.113 0.146 0.837 1.18 0.945 1.47 0.454 0.35 0.194 0.7125 1.58 0.794 3.13 0.789 0.343 0.0215 1.668 2.2 1.12 4.32 0.663 0.346 0.0553 1.257 1.94 0.985 3.82 PRS_PLINK_0.001 220 Benign neoplasm of ovary Female 356 3845 2 neoplasms darkcyan 3845, 356 962, 91 961, 83 961, 97 961, 85 -0.0246 0.0548 0.653 0.1849 0.976 0.876 1.09 -0.0717 0.158 0.65 0.1871 0.931 0.683 1.27 0.0939 0.153 0.539 0.2683 1.1 0.814 1.48 -0.0408 0.158 0.796 0.09906 0.96 0.705 1.31 PRS_PLINK_0.001 221 Benign neoplasm of other female genital organs Female 44 552 2 neoplasms darkcyan 552, 44 138, 13 138, 14 138, 9 138, 8 -0.251 0.153 0.101 0.9974 0.778 0.577 1.05 0.0982 0.388 0.8 0.09677 1.1 0.515 2.36 -0.49 0.438 0.263 0.5805 0.612 0.26 1.44 -0.566 0.451 0.21 0.6785 0.568 0.235 1.37 PRS_PLINK_0.001 222 Benign neoplasm of male genital organs Male 42 392 2 neoplasms darkcyan 392, 42 98, 12 98, 10 98, 8 98, 12 -0.0906 0.155 0.559 0.2529 0.913 0.674 1.24 -0.303 0.45 0.501 0.3003 0.739 0.306 1.79 -0.312 0.474 0.51 0.2922 0.732 0.289 1.85 -0.0135 0.417 0.974 0.01139 0.987 0.436 2.23 PRS_PLINK_0.001 223 Benign neoplasm of kidney and other urinary organs Both 34 418 2 neoplasms darkcyan 418, 34 105, 10 104, 11 104, 9 105, 4 -0.244 0.164 0.138 0.8596 0.784 0.568 1.08 0.233 0.444 0.6 0.2216 1.26 0.528 3.02 0.00355 0.461 0.994 0.002674 1 0.407 2.48 -0.728 0.547 0.183 0.7376 0.483 0.165 1.41 PRS_PLINK_0.001 224 Benign neoplasm of eye Both 21 307 2 neoplasms darkcyan 307, 21 77, 3 77, 6 76, 6 77, 6 0.0306 0.213 0.886 0.05262 1.03 0.679 1.57 0.775 0.656 0.237 0.6251 2.17 0.601 7.85 0.4 0.638 0.531 0.2747 1.49 0.427 5.21 0.438 0.653 0.502 0.2992 1.55 0.431 5.57 PRS_PLINK_0.001 224.1 Benign neoplasm of eye, uveal Both 13 143 2 neoplasms darkcyan 143, 13 36, 2 36, 4 35, 6 36, 1 -0.044 0.292 0.88 0.05543 0.957 0.54 1.7 0.548 0.748 0.463 0.3341 1.73 0.4 7.5 0.578 0.812 0.477 0.3218 1.78 0.363 8.76 -0.372 0.906 0.681 0.1667 0.689 0.117 4.07 PRS_PLINK_0.001 225 Benign neoplasm of brain and other parts of nervous system Both 165 2047 2 neoplasms darkcyan 2047, 165 512, 51 512, 42 511, 26 512, 46 -0.0825 0.0816 0.312 0.5058 0.921 0.785 1.08 -0.167 0.215 0.436 0.3602 0.846 0.555 1.29 -0.649 0.244 0.00789 2.103 0.522 0.324 0.843 -0.0959 0.211 0.65 0.1872 0.909 0.601 1.37 PRS_PLINK_0.001 225.1 Benign neoplasm of brain, cranial nerves, meninges Both 158 1940 2 neoplasms darkcyan 1940, 158 485, 49 485, 39 485, 23 485, 47 -0.0757 0.0838 0.366 0.4364 0.927 0.787 1.09 -0.202 0.221 0.362 0.4415 0.817 0.529 1.26 -0.732 0.255 0.00412 2.385 0.481 0.292 0.793 -0.0369 0.212 0.862 0.06443 0.964 0.636 1.46 PRS_PLINK_0.001 225.2 Benign neoplasm of spinal cord, meninges Both 10 156 2 neoplasms darkcyan 156, 10 39, 1 39, 4 39, 4 39, 1 -0.133 0.312 0.669 0.1745 0.875 0.475 1.61 0.938 0.881 0.287 0.5424 2.56 0.455 14.4 1.19 1.02 0.242 0.6164 3.3 0.447 24.4 0.0755 1.02 0.941 0.0265 1.08 0.147 7.92 PRS_PLINK_0.001 226 Benign neoplasm of thyroid glands Both 63 661 2 neoplasms darkcyan 661, 63 166, 17 165, 20 165, 14 165, 12 -0.0337 0.133 0.8 0.09703 0.967 0.745 1.25 0.16 0.339 0.636 0.1964 1.17 0.604 2.28 -0.169 0.368 0.645 0.1902 0.844 0.411 1.74 -0.278 0.379 0.464 0.3339 0.757 0.36 1.59 PRS_PLINK_0.001 227 Benign neoplasm of other endocrine glands and related structures Both 193 2198 2 neoplasms darkcyan 2198, 193 550, 62 549, 53 549, 42 550, 36 -0.225 0.0752 0.00272 2.566 0.798 0.689 0.925 -0.17 0.195 0.385 0.4145 0.844 0.575 1.24 -0.388 0.207 0.0613 1.212 0.679 0.452 1.02 -0.579 0.217 0.00774 2.111 0.561 0.366 0.858 PRS_PLINK_0.001 227.1 Benign neoplasm of adrenal gland Both 35 455 2 neoplasms darkcyan 455, 35 114, 13 114, 11 113, 4 114, 7 -0.319 0.176 0.0701 1.154 0.727 0.515 1.03 -0.211 0.42 0.615 0.2109 0.81 0.355 1.85 -1.08 0.534 0.0425 1.371 0.339 0.119 0.964 -0.641 0.464 0.168 0.7758 0.527 0.212 1.31 PRS_PLINK_0.001 227.2 Benign neoplasm of parathyroid gland Both 91 934 2 neoplasms darkcyan 934, 91 234, 29 233, 23 233, 21 234, 18 -0.204 0.11 0.0628 1.202 0.816 0.658 1.01 -0.236 0.29 0.416 0.3806 0.79 0.448 1.39 -0.308 0.297 0.3 0.5231 0.735 0.411 1.32 -0.48 0.309 0.12 0.9211 0.619 0.338 1.13 PRS_PLINK_0.001 227.3 Benign neoplasm of pituitary gland and craniopharyngeal duct (pouch) Both 71 819 2 neoplasms darkcyan 819, 71 205, 20 205, 21 204, 18 205, 12 -0.224 0.125 0.0718 1.144 0.799 0.626 1.02 0.0357 0.319 0.911 0.04057 1.04 0.555 1.94 -0.132 0.334 0.692 0.16 0.876 0.456 1.68 -0.538 0.37 0.146 0.8371 0.584 0.283 1.21 PRS_PLINK_0.001 228 Hemangioma and lymphangioma, any site Both 380 4076 2 neoplasms darkcyan 4076, 380 1019, 94 1019, 94 1019, 95 1019, 97 0.0205 0.0547 0.708 0.15 1.02 0.917 1.14 -0.00465 0.151 0.976 0.01076 0.995 0.74 1.34 -0.00541 0.152 0.972 0.01252 0.995 0.739 1.34 0.0607 0.151 0.688 0.1622 1.06 0.79 1.43 PRS_PLINK_0.001 229 Benign neoplasm of unspecified sites Both 546 6129 2 neoplasms darkcyan 6129, 546 1533, 140 1532, 130 1532, 149 1532, 127 -0.024 0.0448 0.592 0.2278 0.976 0.894 1.07 -0.0641 0.127 0.613 0.2126 0.938 0.732 1.2 0.0845 0.123 0.492 0.3077 1.09 0.855 1.39 -0.0962 0.127 0.45 0.3465 0.908 0.708 1.17 PRS_PLINK_0.001 240 Simple and unspecified goiter Both 124 1579 3 endocrine/metabolic brown 1579, 124 395, 31 395, 29 394, 30 395, 34 0.0406 0.0916 0.657 0.1822 1.04 0.87 1.25 -0.0697 0.264 0.792 0.1014 0.933 0.556 1.56 0.0164 0.264 0.951 0.02201 1.02 0.606 1.71 0.0952 0.256 0.71 0.1488 1.1 0.666 1.82 PRS_PLINK_0.001 241 Nontoxic nodular goiter Both 244 2876 3 endocrine/metabolic brown 2876, 244 719, 66 719, 76 719, 60 719, 42 -0.181 0.0676 0.00737 2.132 0.834 0.731 0.953 0.158 0.175 0.366 0.4362 1.17 0.831 1.65 -0.0596 0.185 0.747 0.1265 0.942 0.656 1.35 -0.427 0.204 0.0361 1.442 0.653 0.438 0.973 PRS_PLINK_0.001 241.1 Nontoxic uninodular goiter Both 102 1232 3 endocrine/metabolic brown 1232, 102 308, 29 308, 33 308, 23 308, 17 -0.252 0.104 0.0158 1.8 0.777 0.633 0.954 0.12 0.263 0.648 0.1882 1.13 0.674 1.89 -0.199 0.285 0.486 0.3136 0.82 0.469 1.43 -0.574 0.312 0.066 1.18 0.563 0.305 1.04 PRS_PLINK_0.001 241.2 Nontoxic multinodular goiter Both 151 1725 3 endocrine/metabolic brown 1725, 151 432, 40 431, 48 431, 37 431, 26 -0.148 0.0855 0.0838 1.077 0.863 0.73 1.02 0.229 0.223 0.305 0.5158 1.26 0.812 1.95 -0.0231 0.236 0.922 0.03517 0.977 0.615 1.55 -0.37 0.258 0.152 0.817 0.691 0.416 1.15 PRS_PLINK_0.001 242 Thyrotoxicosis with or without goiter Both 374 4717 3 endocrine/metabolic brown 4717, 374 1180, 88 1179, 105 1179, 113 1179, 68 -0.0747 0.0543 0.169 0.7724 0.928 0.834 1.03 0.192 0.15 0.201 0.6968 1.21 0.903 1.63 0.237 0.148 0.109 0.9622 1.27 0.948 1.69 -0.245 0.166 0.139 0.8577 0.783 0.566 1.08 PRS_PLINK_0.001 242.1 Graves' disease Both 102 1206 3 endocrine/metabolic brown 1206, 102 302, 23 301, 30 301, 28 302, 21 -0.0674 0.104 0.516 0.2875 0.935 0.763 1.15 0.303 0.284 0.286 0.5442 1.35 0.776 2.36 0.183 0.287 0.523 0.2817 1.2 0.685 2.11 -0.0287 0.306 0.925 0.03377 0.972 0.533 1.77 PRS_PLINK_0.001 242.2 Toxic multinodular goiter Both 24 251 3 endocrine/metabolic brown 251, 24 63, 5 63, 7 62, 5 63, 7 -0.0287 0.207 0.889 0.05089 0.972 0.648 1.46 0.476 0.576 0.408 0.3888 1.61 0.52 4.98 0.175 0.608 0.773 0.1116 1.19 0.362 3.93 0.255 0.566 0.652 0.1859 1.29 0.426 3.92 PRS_PLINK_0.001 242.3 Exophthalmos Both 28 342 3 endocrine/metabolic brown 342, 28 86, 6 85, 9 85, 11 86, 2 -0.216 0.199 0.278 0.5565 0.806 0.545 1.19 0.482 0.521 0.355 0.4501 1.62 0.584 4.49 0.573 0.502 0.253 0.5965 1.77 0.663 4.75 -0.943 0.666 0.157 0.8042 0.39 0.106 1.44 PRS_PLINK_0.001 244 Hypothyroidism Both 2830 37215 3 endocrine/metabolic brown 37215, 2830 9303, 733 9304, 731 9303, 687 9304, 679 -0.0382 0.0196 0.0505 1.297 0.962 0.926 1 -0.000953 0.0543 0.986 0.006125 0.999 0.898 1.11 -0.0619 0.0552 0.262 0.581 0.94 0.844 1.05 -0.0725 0.0555 0.191 0.719 0.93 0.834 1.04 PRS_PLINK_0.001 244.1 Secondary hypothyroidism Both 198 2779 3 endocrine/metabolic brown 2779, 198 695, 59 695, 41 694, 51 695, 47 -0.0581 0.0717 0.417 0.3794 0.944 0.82 1.09 -0.347 0.208 0.0965 1.015 0.707 0.47 1.06 -0.173 0.198 0.383 0.4169 0.841 0.571 1.24 -0.209 0.201 0.299 0.5246 0.812 0.548 1.2 PRS_PLINK_0.001 244.2 Acquired hypothyroidism Both 18 236 3 endocrine/metabolic brown 236, 18 59, 4 59, 3 59, 8 59, 3 -0.0258 0.239 0.914 0.03895 0.975 0.61 1.56 -0.127 0.774 0.869 0.06081 0.88 0.193 4.01 0.658 0.587 0.262 0.5817 1.93 0.611 6.1 -0.359 0.743 0.629 0.2015 0.698 0.163 3 PRS_PLINK_0.001 244.4 Hypothyroidism NOS Both 2689 35594 3 endocrine/metabolic brown 35594, 2689 8898, 691 8898, 700 8898, 650 8899, 648 -0.0363 0.02 0.0695 1.158 0.964 0.927 1 0.0149 0.0557 0.789 0.1027 1.01 0.91 1.13 -0.0592 0.0568 0.298 0.5261 0.943 0.843 1.05 -0.0592 0.0569 0.298 0.5253 0.943 0.843 1.05 PRS_PLINK_0.001 245 Thyroiditis Both 60 755 3 endocrine/metabolic brown 755, 60 189, 22 189, 14 188, 13 189, 11 -0.217 0.128 0.0909 1.042 0.805 0.626 1.04 -0.312 0.359 0.384 0.4156 0.732 0.362 1.48 -0.366 0.365 0.316 0.5009 0.694 0.339 1.42 -0.631 0.373 0.0901 1.045 0.532 0.256 1.1 PRS_PLINK_0.001 245.2 Chronic thyroiditis Both 44 579 3 endocrine/metabolic brown 579, 44 145, 18 145, 13 144, 6 145, 7 -0.325 0.153 0.0333 1.477 0.723 0.536 0.975 -0.276 0.382 0.47 0.3281 0.759 0.359 1.6 -0.919 0.466 0.0485 1.314 0.399 0.16 0.994 -0.855 0.439 0.0517 1.287 0.425 0.18 1.01 PRS_PLINK_0.001 245.21 Chronic lymphocytic thyroiditis Both 43 573 3 endocrine/metabolic brown 573, 43 144, 18 143, 12 143, 6 143, 7 -0.302 0.153 0.0492 1.308 0.74 0.548 0.999 -0.293 0.392 0.455 0.3419 0.746 0.346 1.61 -0.913 0.466 0.0501 1.301 0.401 0.161 1 -0.879 0.445 0.0484 1.315 0.415 0.173 0.994 PRS_PLINK_0.001 246 Other disorders of thyroid Both 87 1062 3 endocrine/metabolic brown 1062, 87 266, 22 265, 22 265, 14 266, 29 0.107 0.118 0.366 0.4368 1.11 0.883 1.4 0.0266 0.305 0.93 0.03131 1.03 0.565 1.87 -0.431 0.341 0.207 0.684 0.65 0.333 1.27 0.265 0.29 0.36 0.4438 1.3 0.739 2.3 PRS_PLINK_0.001 250 Diabetes mellitus Both 2758 48126 3 endocrine/metabolic brown 48126, 2758 12032, 700 12031, 672 12031, 709 12032, 677 -0.0134 0.0196 0.496 0.3045 0.987 0.95 1.03 -0.0402 0.0555 0.469 0.3284 0.961 0.862 1.07 0.0195 0.0549 0.722 0.1415 1.02 0.916 1.14 -0.0283 0.0557 0.611 0.214 0.972 0.872 1.08 PRS_PLINK_0.001 250.1 Type 1 diabetes Both 366 7172 3 endocrine/metabolic brown 7172, 366 1793, 95 1793, 97 1793, 86 1793, 88 -0.0345 0.0528 0.514 0.289 0.966 0.871 1.07 0.0385 0.148 0.794 0.1002 1.04 0.778 1.39 -0.11 0.152 0.471 0.3274 0.896 0.665 1.21 -0.072 0.152 0.635 0.197 0.931 0.691 1.25 PRS_PLINK_0.001 250.11 Type 1 diabetes with ketoacidosis Both 18 593 3 endocrine/metabolic brown 593, 18 149, 4 148, 3 148, 6 148, 5 0.0643 0.217 0.767 0.1149 1.07 0.696 1.63 -0.218 0.623 0.726 0.139 0.804 0.237 2.73 0.335 0.574 0.559 0.2522 1.4 0.454 4.31 0.317 0.59 0.591 0.2281 1.37 0.432 4.37 PRS_PLINK_0.001 250.12 Type 1 diabetes with renal manifestations Both 2 193 3 endocrine/metabolic brown 193, 2 49, 0 48, 0 48, 1 48, 1 0.395 0.438 0.367 0.4348 1.48 0.629 3.5 -0.17 1.06 0.873 0.05922 0.843 0.105 6.75 1.05 1.07 0.328 0.4841 2.85 0.349 23.2 0.947 1.15 0.408 0.3888 2.58 0.273 24.3 PRS_PLINK_0.001 250.13 Type 1 diabetes with ophthalmic manifestations Both 65 1248 3 endocrine/metabolic brown 1248, 65 312, 13 312, 18 312, 17 312, 17 0.0715 0.122 0.558 0.2533 1.07 0.845 1.36 0.351 0.357 0.326 0.4872 1.42 0.705 2.86 0.243 0.357 0.497 0.3037 1.27 0.633 2.57 0.259 0.361 0.473 0.3255 1.3 0.639 2.63 PRS_PLINK_0.001 250.14 Type 1 diabetes with neurological manifestations Both 19 419 3 endocrine/metabolic brown 419, 19 105, 3 105, 4 104, 5 105, 7 0.15 0.219 0.493 0.3073 1.16 0.757 1.78 0.273 0.647 0.673 0.1718 1.31 0.37 4.67 0.201 0.635 0.752 0.1241 1.22 0.352 4.24 0.78 0.634 0.219 0.6596 2.18 0.629 7.56 PRS_PLINK_0.001 250.2 Type 2 diabetes Both 2400 43882 3 endocrine/metabolic brown 43882, 2400 10971, 620 10970, 584 10970, 620 10971, 576 -0.0289 0.021 0.169 0.7728 0.972 0.932 1.01 -0.0596 0.0592 0.314 0.5025 0.942 0.839 1.06 0.00682 0.0585 0.907 0.04235 1.01 0.898 1.13 -0.0675 0.0597 0.258 0.588 0.935 0.832 1.05 PRS_PLINK_0.001 250.21 Type 2 diabetes with ketoacidosis Both 11 280 3 endocrine/metabolic brown 280, 11 70, 2 70, 4 70, 2 70, 3 0.261 0.258 0.311 0.5071 1.3 0.783 2.15 0.168 0.769 0.827 0.08238 1.18 0.262 5.34 -0.00886 0.785 0.991 0.003931 0.991 0.213 4.61 0.181 0.769 0.814 0.08963 1.2 0.266 5.41 PRS_PLINK_0.001 250.22 Type 2 diabetes with renal manifestations Both 9 520 3 endocrine/metabolic brown 520, 9 130, 0 130, 1 130, 4 130, 4 1 0.357 0.00506 2.296 2.72 1.35 5.49 0.976 1 0.33 0.481 2.65 0.372 18.9 2.61 1.32 0.048 1.318 13.6 1.02 182 1.96 1.13 0.0815 1.089 7.12 0.782 64.8 PRS_PLINK_0.001 250.23 Type 2 diabetes with ophthalmic manifestations Both 92 2507 3 endocrine/metabolic brown 2507, 92 627, 23 627, 23 626, 24 627, 22 -0.0512 0.104 0.623 0.2055 0.95 0.775 1.17 0.0209 0.29 0.943 0.02568 1.02 0.579 1.8 0.0461 0.288 0.873 0.05916 1.05 0.596 1.84 -0.0535 0.293 0.855 0.06779 0.948 0.533 1.68 PRS_PLINK_0.001 250.24 Type 2 diabetes with neurological manifestations Both 31 1312 3 endocrine/metabolic brown 1312, 31 328, 5 328, 11 328, 8 328, 7 -0.0193 0.174 0.911 0.0403 0.981 0.698 1.38 0.715 0.488 0.143 0.8443 2.04 0.785 5.32 0.388 0.507 0.443 0.3531 1.47 0.546 3.98 0.367 0.518 0.479 0.32 1.44 0.523 3.99 PRS_PLINK_0.001 250.4 Abnormal glucose Both 98 1789 3 endocrine/metabolic brown 1789, 98 448, 25 447, 25 447, 21 447, 27 0.0887 0.101 0.378 0.4229 1.09 0.897 1.33 0.0312 0.282 0.912 0.03998 1.03 0.593 1.79 -0.166 0.294 0.572 0.2426 0.847 0.476 1.51 0.0599 0.28 0.83 0.08069 1.06 0.614 1.84 PRS_PLINK_0.001 250.41 Impaired fasting glucose Both 45 694 3 endocrine/metabolic brown 694, 45 174, 9 173, 10 173, 11 174, 15 0.207 0.147 0.16 0.797 1.23 0.922 1.64 0.0958 0.439 0.827 0.08239 1.1 0.465 2.6 0.201 0.434 0.644 0.1914 1.22 0.522 2.86 0.53 0.418 0.204 0.6898 1.7 0.749 3.85 PRS_PLINK_0.001 250.42 Other abnormal glucose Both 53 1098 3 endocrine/metabolic brown 1098, 53 275, 14 274, 16 274, 11 275, 12 -0.0209 0.134 0.876 0.05757 0.979 0.754 1.27 0.112 0.361 0.755 0.1218 1.12 0.552 2.27 -0.258 0.387 0.505 0.2967 0.772 0.362 1.65 -0.291 0.387 0.452 0.3451 0.747 0.35 1.6 PRS_PLINK_0.001 250.5 Glycosuria or Acetonuria Both 20 342 3 endocrine/metabolic brown 342, 20 86, 1 85, 5 85, 6 86, 8 0.585 0.234 0.0126 1.901 1.79 1.13 2.84 1.37 0.824 0.0954 1.021 3.95 0.786 19.8 1.43 0.797 0.0736 1.133 4.16 0.873 19.8 1.69 0.814 0.0374 1.427 5.44 1.1 26.8 PRS_PLINK_0.001 250.6 Polyneuropathy in diabetes Both 30 928 3 endocrine/metabolic brown 928, 30 232, 6 232, 7 232, 8 232, 9 0.0639 0.176 0.716 0.145 1.07 0.755 1.5 0.157 0.503 0.755 0.1223 1.17 0.436 3.14 0.158 0.492 0.748 0.1261 1.17 0.446 3.07 0.293 0.483 0.544 0.2643 1.34 0.52 3.45 PRS_PLINK_0.001 250.7 Diabetic retinopathy Both 151 3332 3 endocrine/metabolic brown 3332, 151 833, 36 833, 41 833, 40 833, 34 -0.0238 0.0824 0.772 0.1122 0.976 0.831 1.15 0.144 0.229 0.529 0.2763 1.15 0.737 1.81 0.114 0.23 0.622 0.2066 1.12 0.713 1.76 -0.069 0.24 0.774 0.1114 0.933 0.583 1.49 PRS_PLINK_0.001 251.1 Hypoglycemia Both 91 2401 3 endocrine/metabolic brown 2401, 91 601, 19 600, 24 600, 25 600, 23 0.0742 0.106 0.484 0.3153 1.08 0.875 1.33 0.249 0.302 0.41 0.3872 1.28 0.709 2.32 0.278 0.299 0.353 0.4524 1.32 0.734 2.37 0.19 0.307 0.536 0.2711 1.21 0.663 2.21 PRS_PLINK_0.001 252 Disorders of parathyroid gland Both 182 2189 3 endocrine/metabolic brown 2189, 182 548, 44 547, 42 547, 63 547, 33 -0.0789 0.0766 0.303 0.5188 0.924 0.795 1.07 -0.0365 0.222 0.869 0.06078 0.964 0.624 1.49 0.347 0.206 0.0923 1.035 1.41 0.945 2.12 -0.297 0.237 0.209 0.6797 0.743 0.467 1.18 PRS_PLINK_0.001 252.1 Hyperparathyroidism Both 167 1936 3 endocrine/metabolic brown 1936, 167 484, 40 484, 35 484, 61 484, 31 -0.0584 0.0797 0.464 0.3338 0.943 0.807 1.1 -0.121 0.238 0.612 0.213 0.886 0.556 1.41 0.392 0.213 0.066 1.181 1.48 0.974 2.25 -0.267 0.246 0.277 0.557 0.766 0.473 1.24 PRS_PLINK_0.001 252.2 Hypoparathyroidism Both 27 386 3 endocrine/metabolic brown 386, 27 97, 6 96, 11 96, 4 97, 6 -0.0144 0.197 0.942 0.02601 0.986 0.669 1.45 0.774 0.531 0.145 0.8398 2.17 0.767 6.14 -0.261 0.588 0.657 0.1826 0.77 0.243 2.44 0.165 0.572 0.773 0.1121 1.18 0.384 3.62 PRS_PLINK_0.001 253 Disorders of the pituitary gland and its hypothalamic control Both 130 1696 3 endocrine/metabolic brown 1696, 130 424, 39 424, 35 424, 32 424, 24 -0.114 0.0888 0.2 0.6993 0.892 0.75 1.06 -0.1 0.239 0.675 0.1709 0.904 0.566 1.45 -0.182 0.244 0.456 0.3411 0.834 0.517 1.34 -0.497 0.264 0.0598 1.223 0.608 0.363 1.02 PRS_PLINK_0.001 253.1 Pituitary hyperfunction Both 42 497 3 endocrine/metabolic brown 497, 42 125, 10 124, 13 124, 11 124, 8 -0.0437 0.151 0.772 0.1125 0.957 0.713 1.29 0.254 0.423 0.548 0.2609 1.29 0.563 2.95 0.216 0.434 0.619 0.2085 1.24 0.53 2.9 -0.254 0.466 0.586 0.232 0.776 0.311 1.93 PRS_PLINK_0.001 253.11 Acromegaly and gigantism Both 18 224 3 endocrine/metabolic brown 224, 18 56, 7 56, 3 56, 4 56, 4 -0.218 0.217 0.314 0.5029 0.804 0.526 1.23 -0.786 0.653 0.229 0.6405 0.456 0.127 1.64 -0.388 0.604 0.52 0.2837 0.678 0.207 2.22 -0.763 0.655 0.244 0.6119 0.466 0.129 1.68 PRS_PLINK_0.001 253.2 Pituitary hypofunction Both 55 642 3 endocrine/metabolic brown 642, 55 161, 18 160, 16 160, 12 161, 9 -0.199 0.133 0.134 0.8729 0.82 0.632 1.06 -0.0668 0.351 0.849 0.07107 0.935 0.47 1.86 -0.351 0.385 0.363 0.4403 0.704 0.331 1.5 -0.61 0.407 0.134 0.8722 0.543 0.245 1.21 PRS_PLINK_0.001 253.3 Diabetes insipidus Both 15 243 3 endocrine/metabolic brown 243, 15 61, 4 61, 4 60, 3 61, 4 0.00861 0.248 0.972 0.01221 1.01 0.621 1.64 0.352 0.687 0.609 0.2156 1.42 0.37 5.47 -0.425 0.693 0.54 0.2679 0.654 0.168 2.54 -0.0512 0.705 0.942 0.0259 0.95 0.239 3.78 PRS_PLINK_0.001 253.7 Other disorders of neurohypophysis Both 21 340 3 endocrine/metabolic brown 340, 21 85, 9 85, 6 85, 5 85, 1 -0.419 0.222 0.0591 1.229 0.658 0.426 1.02 -0.474 0.521 0.363 0.4396 0.623 0.224 1.73 -0.603 0.541 0.265 0.5769 0.547 0.189 1.58 -1.88 0.803 0.0194 1.711 0.153 0.0318 0.739 PRS_PLINK_0.001 255 Disorders of adrenal glands Both 107 1630 3 endocrine/metabolic brown 1630, 107 408, 27 407, 24 407, 28 408, 28 0.0833 0.102 0.415 0.3823 1.09 0.89 1.33 -0.115 0.283 0.685 0.1645 0.892 0.513 1.55 0.0108 0.271 0.968 0.01399 1.01 0.594 1.72 0.0209 0.272 0.939 0.02742 1.02 0.599 1.74 PRS_PLINK_0.001 255.1 Adrenal hyperfunction Both 28 482 3 endocrine/metabolic brown 482, 28 121, 10 120, 8 120, 3 121, 7 -0.2 0.192 0.298 0.5264 0.819 0.562 1.19 -0.19 0.461 0.68 0.1674 0.827 0.335 2.04 -0.995 0.582 0.0871 1.06 0.37 0.118 1.16 -0.313 0.483 0.517 0.2864 0.731 0.284 1.88 PRS_PLINK_0.001 255.11 Cushing's syndrome Both 17 256 3 endocrine/metabolic brown 256, 17 64, 6 64, 3 64, 4 64, 4 -0.183 0.23 0.426 0.3703 0.833 0.53 1.31 -0.536 0.642 0.404 0.3938 0.585 0.166 2.06 -0.294 0.603 0.625 0.2038 0.745 0.229 2.43 -0.331 0.62 0.593 0.2267 0.718 0.213 2.42 PRS_PLINK_0.001 255.12 Hyperaldosteronism Both 12 206 3 endocrine/metabolic brown 206, 12 52, 4 51, 3 51, 2 52, 3 -0.123 0.277 0.658 0.1819 0.884 0.514 1.52 -0.203 0.728 0.78 0.1078 0.816 0.196 3.4 -0.468 0.747 0.531 0.2749 0.626 0.145 2.71 -0.302 0.721 0.676 0.1704 0.739 0.18 3.04 PRS_PLINK_0.001 255.2 Adrenal hypofunction Both 66 918 3 endocrine/metabolic brown 918, 66 230, 14 229, 15 229, 18 230, 19 0.115 0.13 0.375 0.426 1.12 0.87 1.45 0.124 0.372 0.739 0.1312 1.13 0.546 2.34 0.247 0.352 0.483 0.3157 1.28 0.642 2.55 0.294 0.353 0.405 0.3929 1.34 0.672 2.68 PRS_PLINK_0.001 255.21 Glucocorticoid deficiency Both 66 910 3 endocrine/metabolic brown 910, 66 228, 14 227, 15 227, 18 228, 19 0.12 0.13 0.357 0.4478 1.13 0.874 1.45 0.0988 0.371 0.79 0.1023 1.1 0.533 2.28 0.239 0.352 0.498 0.303 1.27 0.637 2.53 0.295 0.354 0.404 0.3939 1.34 0.672 2.69 PRS_PLINK_0.001 256 Ovarian dysfunction Female 78 661 3 endocrine/metabolic brown 661, 78 166, 18 165, 19 165, 20 165, 21 0.033 0.119 0.782 0.1067 1.03 0.818 1.31 0.0809 0.342 0.813 0.08976 1.08 0.554 2.12 0.164 0.338 0.627 0.2025 1.18 0.608 2.28 0.231 0.334 0.489 0.3106 1.26 0.655 2.42 PRS_PLINK_0.001 256.4 Polycystic ovaries Female 61 580 3 endocrine/metabolic brown 580, 61 145, 17 145, 13 145, 16 145, 15 -0.0227 0.133 0.865 0.06315 0.978 0.753 1.27 -0.251 0.374 0.502 0.2997 0.778 0.374 1.62 -0.00544 0.362 0.988 0.005238 0.995 0.489 2.02 -0.0849 0.362 0.815 0.08902 0.919 0.452 1.87 PRS_PLINK_0.001 257 Testicular dysfunction Male 36 388 3 endocrine/metabolic brown 388, 36 97, 11 97, 10 97, 6 97, 9 -0.0839 0.172 0.625 0.2041 0.92 0.657 1.29 -0.155 0.442 0.727 0.1385 0.857 0.36 2.04 -0.537 0.494 0.278 0.5566 0.585 0.222 1.54 -0.237 0.457 0.604 0.2192 0.789 0.322 1.93 PRS_PLINK_0.001 257.1 Testicular hypofunction Male 32 373 3 endocrine/metabolic brown 373, 32 94, 10 93, 8 93, 6 93, 8 -0.118 0.182 0.515 0.2883 0.888 0.622 1.27 -0.237 0.472 0.616 0.2106 0.789 0.313 1.99 -0.499 0.501 0.319 0.4959 0.607 0.227 1.62 -0.223 0.479 0.642 0.1928 0.8 0.313 2.05 PRS_PLINK_0.001 258 Iatrogenic endocrine disorders Both 19 258 3 endocrine/metabolic brown 258, 19 65, 8 64, 3 64, 5 65, 3 -0.316 0.22 0.15 0.8228 0.729 0.474 1.12 -1.07 0.688 0.119 0.9246 0.342 0.0887 1.32 -0.168 0.564 0.766 0.1159 0.845 0.28 2.55 -0.996 0.639 0.119 0.9232 0.369 0.105 1.29 PRS_PLINK_0.001 259 Other endocrine disorders Both 31 419 3 endocrine/metabolic brown 419, 31 105, 6 105, 10 104, 7 105, 8 0.0606 0.178 0.733 0.1348 1.06 0.75 1.51 0.481 0.494 0.33 0.481 1.62 0.614 4.26 0.263 0.53 0.619 0.2081 1.3 0.461 3.68 0.557 0.548 0.309 0.5101 1.75 0.597 5.11 PRS_PLINK_0.001 260 Protein-calorie malnutrition Both 19 482 3 endocrine/metabolic brown 482, 19 121, 4 120, 5 120, 3 121, 7 0.0727 0.219 0.74 0.1306 1.08 0.7 1.65 0.318 0.598 0.595 0.2257 1.37 0.426 4.44 -0.151 0.631 0.811 0.09123 0.86 0.249 2.96 0.522 0.577 0.366 0.4369 1.69 0.544 5.22 PRS_PLINK_0.001 260.1 Cachexia Both 3 109 3 endocrine/metabolic brown 109, 3 28, 2 27, 0 27, 1 27, 0 -0.626 0.476 0.188 0.7265 0.535 0.21 1.36 -1.92 1.4 0.169 0.7731 0.146 0.00947 2.26 0.342 1.09 0.754 0.1223 1.41 0.165 12 -1.34 1.21 0.271 0.5667 0.263 0.0243 2.84 PRS_PLINK_0.001 260.6 Anorexia Both 110 2030 3 endocrine/metabolic brown 2030, 110 508, 27 507, 25 507, 33 508, 25 0.019 0.0978 0.846 0.07282 1.02 0.842 1.23 -0.0625 0.277 0.822 0.08539 0.939 0.546 1.62 0.214 0.262 0.413 0.3837 1.24 0.741 2.07 -0.0578 0.279 0.836 0.07791 0.944 0.547 1.63 PRS_PLINK_0.001 261 Vitamin deficiency Both 181 3040 3 endocrine/metabolic brown 3040, 181 760, 38 760, 40 760, 57 760, 46 0.0892 0.0776 0.25 0.6015 1.09 0.939 1.27 0.0671 0.228 0.768 0.1144 1.07 0.684 1.67 0.416 0.213 0.051 1.293 1.52 0.998 2.3 0.195 0.223 0.382 0.4174 1.21 0.785 1.88 PRS_PLINK_0.001 261.2 Vitamin B-complex deficiencies Both 107 1867 3 endocrine/metabolic brown 1867, 107 467, 24 467, 24 466, 31 467, 28 0.0941 0.0996 0.345 0.4624 1.1 0.904 1.34 -0.0308 0.288 0.915 0.03865 0.97 0.552 1.7 0.251 0.275 0.361 0.4422 1.29 0.75 2.2 0.0985 0.283 0.728 0.1381 1.1 0.634 1.92 PRS_PLINK_0.001 261.4 Vitamin D deficiency Both 72 1187 3 endocrine/metabolic brown 1187, 72 297, 14 297, 19 296, 23 297, 16 0.0251 0.123 0.838 0.07666 1.03 0.806 1.31 0.385 0.35 0.272 0.5649 1.47 0.739 2.92 0.584 0.342 0.0874 1.059 1.79 0.918 3.5 0.172 0.357 0.631 0.2002 1.19 0.589 2.39 PRS_PLINK_0.001 261.41 Rickets or osteomalacia Both 12 190 3 endocrine/metabolic brown 190, 12 48, 1 47, 3 47, 3 48, 5 0.539 0.319 0.0906 1.043 1.71 0.918 3.2 0.875 0.87 0.315 0.5021 2.4 0.436 13.2 0.81 0.884 0.359 0.4449 2.25 0.398 12.7 1.51 0.878 0.085 1.071 4.54 0.812 25.4 PRS_PLINK_0.001 262 Mineral deficiency NEC Both 51 591 3 endocrine/metabolic brown 591, 51 147, 12 148, 20 147, 9 148, 10 -0.0351 0.142 0.804 0.0945 0.965 0.731 1.28 0.489 0.369 0.185 0.7319 1.63 0.791 3.36 -0.108 0.44 0.805 0.09399 0.897 0.379 2.12 -0.087 0.436 0.842 0.07475 0.917 0.39 2.16 PRS_PLINK_0.001 269 Proteinuria Both 58 857 3 endocrine/metabolic brown 857, 58 215, 14 214, 19 214, 10 214, 15 -0.0371 0.128 0.772 0.1124 0.964 0.75 1.24 0.393 0.356 0.27 0.5691 1.48 0.737 2.97 -0.342 0.403 0.395 0.4032 0.71 0.323 1.56 0.0369 0.369 0.92 0.0361 1.04 0.504 2.14 PRS_PLINK_0.001 270 Disorders of protein plasma/amino-acid transport and metabolism Both 49 741 3 endocrine/metabolic brown 741, 49 186, 8 185, 17 185, 11 185, 13 0.111 0.144 0.444 0.353 1.12 0.842 1.48 0.792 0.419 0.0587 1.232 2.21 0.971 5.02 0.344 0.447 0.443 0.354 1.41 0.587 3.39 0.43 0.434 0.322 0.4926 1.54 0.657 3.6 PRS_PLINK_0.001 270.3 Disorders of plasma protein metabolism Both 42 617 3 endocrine/metabolic brown 617, 42 155, 8 154, 14 154, 10 154, 10 0.0845 0.156 0.588 0.2305 1.09 0.802 1.48 0.597 0.432 0.166 0.7788 1.82 0.78 4.23 0.238 0.457 0.602 0.2202 1.27 0.518 3.11 0.11 0.458 0.81 0.09152 1.12 0.455 2.74 PRS_PLINK_0.001 270.32 Paraproteinemia Both 33 451 3 endocrine/metabolic brown 451, 33 113, 5 113, 12 112, 10 113, 6 0.0971 0.179 0.588 0.2307 1.1 0.776 1.57 0.795 0.51 0.119 0.9235 2.21 0.814 6.02 0.69 0.526 0.19 0.7216 1.99 0.711 5.59 0.0664 0.559 0.906 0.0431 1.07 0.357 3.2 PRS_PLINK_0.001 270.33 Amyloidosis Both 13 277 3 endocrine/metabolic brown 277, 13 70, 4 69, 2 69, 5 69, 2 0.0175 0.287 0.951 0.02163 1.02 0.579 1.79 -0.423 0.701 0.546 0.2626 0.655 0.166 2.59 0.0561 0.662 0.932 0.03037 1.06 0.289 3.87 -0.642 0.783 0.412 0.385 0.526 0.113 2.44 PRS_PLINK_0.001 270.35 Macroglobulinemia Both 9 155 3 endocrine/metabolic brown 155, 9 39, 3 39, 1 38, 1 39, 4 0.134 0.294 0.649 0.188 1.14 0.643 2.03 -0.483 0.913 0.597 0.2243 0.617 0.103 3.69 -0.714 0.842 0.396 0.402 0.49 0.094 2.55 0.114 0.748 0.878 0.05632 1.12 0.259 4.85 PRS_PLINK_0.001 271 Disorders of carbohydrate transport and metabolism Both 31 416 3 endocrine/metabolic brown 416, 31 104, 5 104, 7 104, 10 104, 9 0.375 0.184 0.0419 1.378 1.45 1.01 2.09 0.337 0.547 0.538 0.2692 1.4 0.48 4.09 0.686 0.525 0.192 0.7173 1.99 0.709 5.56 0.542 0.538 0.314 0.5031 1.72 0.599 4.94 PRS_PLINK_0.001 271.3 Intestinal disaccharidase deficiencies and disaccharide malabsorption Both 28 356 3 endocrine/metabolic brown 356, 28 89, 5 89, 7 89, 8 89, 8 0.355 0.192 0.0638 1.195 1.43 0.98 2.08 0.35 0.547 0.522 0.2823 1.42 0.486 4.14 0.471 0.55 0.392 0.4069 1.6 0.545 4.7 0.459 0.557 0.41 0.3869 1.58 0.531 4.71 PRS_PLINK_0.001 272 Disorders of lipoid metabolism Both 6032 61984 3 endocrine/metabolic brown 61984, 6032 15495, 1473 15496, 1550 15496, 1514 15496, 1495 0.00536 0.0136 0.694 0.1584 1.01 0.979 1.03 0.0497 0.0384 0.197 0.7066 1.05 0.975 1.13 0.032 0.0387 0.409 0.3883 1.03 0.957 1.11 0.0233 0.0389 0.549 0.2605 1.02 0.948 1.1 PRS_PLINK_0.001 272.1 Hyperlipidemia Both 6014 61915 3 endocrine/metabolic brown 61915, 6014 15478, 1470 15479, 1542 15478, 1509 15479, 1493 0.00524 0.0137 0.701 0.1541 1.01 0.979 1.03 0.0467 0.0385 0.225 0.6473 1.05 0.972 1.13 0.0305 0.0388 0.431 0.3651 1.03 0.956 1.11 0.0239 0.039 0.54 0.2677 1.02 0.949 1.11 PRS_PLINK_0.001 272.11 Hypercholesterolemia Both 5571 59897 3 endocrine/metabolic brown 59897, 5571 14974, 1359 14974, 1418 14974, 1391 14974, 1403 0.0122 0.0142 0.388 0.4111 1.01 0.985 1.04 0.0433 0.04 0.278 0.5557 1.04 0.966 1.13 0.0303 0.0402 0.451 0.3456 1.03 0.953 1.12 0.0437 0.0403 0.278 0.5562 1.04 0.965 1.13 PRS_PLINK_0.001 272.12 Hyperglyceridemia Both 11 164 3 endocrine/metabolic brown 164, 11 41, 3 41, 1 41, 5 41, 2 -0.0614 0.279 0.826 0.08302 0.94 0.544 1.63 -0.694 0.842 0.41 0.3877 0.499 0.0959 2.6 0.356 0.703 0.613 0.2128 1.43 0.36 5.66 -0.0653 0.779 0.933 0.03002 0.937 0.203 4.32 PRS_PLINK_0.001 272.13 Mixed hyperlipidemia Both 26 425 3 endocrine/metabolic brown 425, 26 107, 5 106, 5 106, 8 106, 8 0.181 0.178 0.309 0.5097 1.2 0.846 1.7 0.134 0.574 0.815 0.08876 1.14 0.371 3.52 0.426 0.534 0.425 0.3713 1.53 0.538 4.36 0.462 0.541 0.394 0.4047 1.59 0.549 4.58 PRS_PLINK_0.001 272.9 Unspecified disorder of lipoid metabolism Both 34 556 3 endocrine/metabolic brown 556, 34 139, 4 139, 13 139, 12 139, 5 0.0675 0.172 0.694 0.1583 1.07 0.764 1.5 1.06 0.528 0.0439 1.358 2.9 1.03 8.15 0.981 0.528 0.0633 1.199 2.67 0.947 7.51 0.071 0.619 0.909 0.04155 1.07 0.319 3.62 PRS_PLINK_0.001 274 Gout and other crystal arthropathies Both 577 9226 3 endocrine/metabolic brown 9226, 577 2306, 137 2306, 144 2306, 144 2307, 152 0.0493 0.0429 0.251 0.601 1.05 0.966 1.14 0.055 0.122 0.653 0.1849 1.06 0.831 1.34 0.051 0.122 0.677 0.1693 1.05 0.828 1.34 0.132 0.122 0.278 0.5555 1.14 0.899 1.45 PRS_PLINK_0.001 274.1 Gout Both 482 7841 3 endocrine/metabolic brown 7841, 482 1960, 114 1960, 122 1960, 125 1960, 121 0.0496 0.0466 0.288 0.5411 1.05 0.959 1.15 0.0699 0.133 0.6 0.2215 1.07 0.826 1.39 0.0983 0.133 0.459 0.338 1.1 0.85 1.43 0.0916 0.134 0.495 0.3056 1.1 0.842 1.43 PRS_PLINK_0.001 274.11 Gouty arthropathy Both 8 251 3 endocrine/metabolic brown 251, 8 63, 4 63, 1 62, 0 63, 3 -0.0483 0.297 0.871 0.06008 0.953 0.532 1.71 -1.51 0.87 0.0838 1.077 0.222 0.0403 1.22 -2.56 1.24 0.0395 1.403 0.0775 0.00678 0.885 -0.376 0.722 0.602 0.2202 0.686 0.167 2.83 PRS_PLINK_0.001 274.2 Crystal arthropathies Both 106 1560 3 endocrine/metabolic brown 1560, 106 390, 26 390, 25 390, 24 390, 31 0.0589 0.0986 0.551 0.2591 1.06 0.874 1.29 -0.0724 0.283 0.798 0.09813 0.93 0.534 1.62 -0.0697 0.284 0.806 0.09363 0.933 0.535 1.63 0.167 0.271 0.539 0.2683 1.18 0.694 2.01 PRS_PLINK_0.001 274.21 Chondrocalcinosis Both 102 1426 3 endocrine/metabolic brown 1426, 102 357, 24 356, 25 356, 23 357, 30 0.0602 0.1 0.548 0.2616 1.06 0.873 1.29 0.0332 0.289 0.908 0.04168 1.03 0.587 1.82 -0.0275 0.292 0.925 0.03389 0.973 0.549 1.72 0.226 0.279 0.418 0.3792 1.25 0.725 2.17 PRS_PLINK_0.001 275 Disorders of mineral metabolism Both 280 5222 3 endocrine/metabolic brown 5222, 280 1305, 75 1305, 65 1305, 78 1306, 62 -0.0481 0.0603 0.425 0.3712 0.953 0.847 1.07 -0.145 0.173 0.402 0.3955 0.865 0.617 1.21 0.0317 0.166 0.849 0.07125 1.03 0.746 1.43 -0.182 0.175 0.3 0.5233 0.834 0.591 1.18 PRS_PLINK_0.001 275.1 Disorders of iron metabolism Both 131 1634 4 hematopoietic darkorange1 1634, 131 409, 33 408, 34 408, 35 409, 29 0.0301 0.0873 0.73 0.1366 1.03 0.868 1.22 0.0124 0.249 0.96 0.01753 1.01 0.621 1.65 0.06 0.25 0.81 0.09153 1.06 0.651 1.73 -0.136 0.259 0.601 0.2211 0.873 0.525 1.45 PRS_PLINK_0.001 275.3 Disorders of magnesium metabolism Both 23 931 3 endocrine/metabolic brown 931, 23 233, 8 233, 3 232, 8 233, 4 -0.201 0.2 0.316 0.4999 0.818 0.552 1.21 -1.05 0.589 0.0733 1.135 0.348 0.11 1.1 -0.0148 0.466 0.975 0.01117 0.985 0.395 2.46 -0.756 0.545 0.165 0.7817 0.47 0.162 1.37 PRS_PLINK_0.001 275.5 Disorders of calcium/phosphorus metabolism Both 135 3015 3 endocrine/metabolic brown 3015, 135 753, 37 754, 31 753, 37 754, 30 -0.0729 0.0864 0.398 0.3997 0.93 0.785 1.1 -0.171 0.245 0.485 0.3141 0.843 0.521 1.36 -0.00801 0.235 0.973 0.012 0.992 0.626 1.57 -0.223 0.247 0.366 0.4361 0.8 0.492 1.3 PRS_PLINK_0.001 275.53 Disorders of phosphorus metabolism Both 15 448 3 endocrine/metabolic brown 448, 15 112, 3 112, 2 112, 4 112, 6 0.186 0.239 0.438 0.359 1.2 0.753 1.93 -0.406 0.714 0.57 0.2443 0.666 0.164 2.7 0.166 0.649 0.798 0.09789 1.18 0.331 4.21 0.761 0.635 0.231 0.6364 2.14 0.616 7.44 PRS_PLINK_0.001 276 Disorders of fluid, electrolyte, and acid-base balance Both 726 18056 3 endocrine/metabolic brown 18056, 726 4513, 191 4514, 167 4514, 179 4514, 189 0.00643 0.0379 0.865 0.06278 1.01 0.934 1.08 -0.136 0.108 0.207 0.6844 0.873 0.707 1.08 -0.077 0.106 0.468 0.3302 0.926 0.752 1.14 -0.000807 0.105 0.994 0.002676 0.999 0.814 1.23 PRS_PLINK_0.001 276.1 Electrolyte imbalance Both 402 10103 3 endocrine/metabolic brown 10103, 402 2525, 112 2526, 87 2525, 103 2526, 100 -0.0291 0.0507 0.566 0.2471 0.971 0.879 1.07 -0.261 0.145 0.0711 1.148 0.77 0.58 1.02 -0.0995 0.139 0.473 0.3252 0.905 0.69 1.19 -0.114 0.14 0.415 0.3816 0.892 0.678 1.17 PRS_PLINK_0.001 276.11 Hyperosmolality and/or hypernatremia Both 11 613 3 endocrine/metabolic brown 613, 11 154, 2 153, 4 153, 2 153, 3 0.0161 0.281 0.954 0.02038 1.02 0.586 1.76 0.457 0.669 0.495 0.3057 1.58 0.425 5.87 0.0833 0.759 0.913 0.03968 1.09 0.245 4.81 -0.252 0.839 0.764 0.1168 0.777 0.15 4.03 PRS_PLINK_0.001 276.12 Hyposmolality and/or hyponatremia Both 187 4566 3 endocrine/metabolic brown 4566, 187 1142, 56 1141, 42 1141, 48 1142, 41 -0.104 0.0743 0.163 0.788 0.902 0.779 1.04 -0.3 0.205 0.144 0.8429 0.741 0.496 1.11 -0.155 0.198 0.434 0.3628 0.856 0.58 1.26 -0.323 0.208 0.12 0.9213 0.724 0.482 1.09 PRS_PLINK_0.001 276.13 Hyperpotassemia Both 81 2352 3 endocrine/metabolic brown 2352, 81 588, 19 588, 18 588, 25 588, 19 -0.0248 0.11 0.822 0.08509 0.976 0.786 1.21 -0.0353 0.319 0.912 0.04003 0.965 0.517 1.8 0.275 0.3 0.358 0.4455 1.32 0.732 2.37 0.036 0.317 0.91 0.04112 1.04 0.557 1.93 PRS_PLINK_0.001 276.14 Hypopotassemia Both 153 3536 3 endocrine/metabolic brown 3536, 153 883, 44 884, 27 884, 43 884, 39 0.0144 0.0808 0.858 0.06632 1.01 0.866 1.19 -0.527 0.245 0.0311 1.507 0.59 0.366 0.953 -0.0403 0.216 0.852 0.06943 0.961 0.629 1.47 -0.0897 0.222 0.687 0.1633 0.914 0.591 1.41 PRS_PLINK_0.001 276.4 Acid-base balance disorder Both 85 2890 3 endocrine/metabolic brown 2890, 85 723, 16 722, 25 722, 17 723, 27 0.162 0.111 0.142 0.8477 1.18 0.947 1.46 0.415 0.31 0.181 0.7419 1.51 0.824 2.78 0.0283 0.334 0.932 0.03037 1.03 0.534 1.98 0.511 0.307 0.0961 1.017 1.67 0.913 3.04 PRS_PLINK_0.001 276.41 Acidosis Both 72 2624 3 endocrine/metabolic brown 2624, 72 656, 13 656, 24 656, 11 656, 24 0.137 0.119 0.251 0.5997 1.15 0.907 1.45 0.554 0.332 0.0954 1.02 1.74 0.908 3.33 -0.201 0.383 0.6 0.2217 0.818 0.386 1.73 0.586 0.333 0.0784 1.106 1.8 0.936 3.45 PRS_PLINK_0.001 276.42 Alkalosis Both 12 279 3 endocrine/metabolic brown 279, 12 70, 2 70, 1 69, 6 70, 3 0.332 0.279 0.235 0.6291 1.39 0.806 2.41 0.58 1.01 0.565 0.2481 1.79 0.248 12.9 1.01 0.745 0.175 0.7561 2.75 0.637 11.8 0.934 0.854 0.274 0.562 2.55 0.477 13.6 PRS_PLINK_0.001 276.5 Hypovolemia Both 287 7019 3 endocrine/metabolic brown 7019, 287 1754, 68 1755, 70 1754, 78 1755, 71 0.0212 0.0599 0.723 0.1408 1.02 0.908 1.15 0.0157 0.172 0.927 0.03283 1.02 0.725 1.42 0.119 0.168 0.478 0.321 1.13 0.81 1.57 0.0589 0.172 0.731 0.136 1.06 0.758 1.48 PRS_PLINK_0.001 276.6 Fluid overload Both 22 1079 3 endocrine/metabolic brown 1079, 22 270, 8 270, 5 269, 6 270, 3 -0.193 0.198 0.329 0.4831 0.824 0.559 1.22 -0.383 0.509 0.452 0.345 0.682 0.251 1.85 -0.238 0.486 0.625 0.2039 0.789 0.304 2.05 -0.719 0.582 0.217 0.6635 0.487 0.156 1.53 PRS_PLINK_0.001 276.8 Polydipsia Both 14 323 3 endocrine/metabolic brown 323, 14 81, 1 81, 1 80, 4 81, 8 0.754 0.279 0.00687 2.163 2.13 1.23 3.67 -0.296 0.87 0.734 0.1346 0.744 0.135 4.09 1.38 0.934 0.14 0.8537 3.97 0.636 24.8 1.52 0.794 0.0559 1.253 4.57 0.962 21.7 PRS_PLINK_0.001 277 Other disorders of metabolism Both 118 2237 3 endocrine/metabolic brown 2237, 118 560, 31 559, 26 559, 31 559, 30 0.0406 0.0948 0.668 0.1751 1.04 0.865 1.25 -0.158 0.265 0.551 0.2586 0.854 0.507 1.44 -0.000896 0.257 0.997 0.001212 0.999 0.604 1.65 -0.0438 0.26 0.866 0.06257 0.957 0.576 1.59 PRS_PLINK_0.001 277.4 Disorders of bilirubin excretion Both 83 931 3 endocrine/metabolic brown 931, 83 233, 17 233, 25 232, 18 233, 23 0.0356 0.113 0.752 0.1237 1.04 0.831 1.29 0.261 0.322 0.418 0.379 1.3 0.691 2.44 0.00108 0.342 0.997 0.001095 1 0.512 1.96 0.239 0.325 0.462 0.335 1.27 0.672 2.4 PRS_PLINK_0.001 277.5 Other disorders of lipoid metabolism Both 39 561 3 endocrine/metabolic brown 561, 39 141, 12 140, 5 140, 10 140, 12 -0.087 0.161 0.588 0.2308 0.917 0.669 1.26 -0.819 0.506 0.105 0.9779 0.441 0.164 1.19 -0.195 0.422 0.644 0.1913 0.823 0.36 1.88 0.0129 0.402 0.974 0.01129 1.01 0.461 2.23 PRS_PLINK_0.001 277.51 Lipoprotein disorders Both 8 115 3 endocrine/metabolic brown 115, 8 29, 2 29, 2 28, 3 29, 1 -0.0985 0.326 0.762 0.1179 0.906 0.479 1.72 -0.137 0.934 0.883 0.05392 0.872 0.14 5.44 0.259 0.848 0.76 0.1193 1.3 0.246 6.84 -0.921 0.968 0.342 0.4662 0.398 0.0597 2.66 PRS_PLINK_0.001 278 Overweight, obesity and other hyperalimentation Both 1681 27901 3 endocrine/metabolic brown 27901, 1681 6976, 410 6975, 403 6975, 418 6975, 450 0.0333 0.0252 0.186 0.7314 1.03 0.984 1.09 -0.0161 0.0721 0.823 0.08455 0.984 0.854 1.13 0.019 0.0716 0.79 0.1023 1.02 0.886 1.17 0.0854 0.0707 0.227 0.6439 1.09 0.948 1.25 PRS_PLINK_0.001 278.1 Obesity Both 1652 27504 3 endocrine/metabolic brown 27504, 1652 6876, 398 6876, 398 6876, 412 6876, 444 0.0379 0.0254 0.136 0.8679 1.04 0.988 1.09 0.00154 0.0729 0.983 0.007393 1 0.868 1.16 0.0332 0.0723 0.646 0.1899 1.03 0.897 1.19 0.101 0.0714 0.157 0.8047 1.11 0.962 1.27 PRS_PLINK_0.001 278.3 Localized adiposity Both 15 236 3 endocrine/metabolic brown 236, 15 59, 4 59, 4 59, 3 59, 4 -0.0864 0.251 0.731 0.1362 0.917 0.561 1.5 -0.168 0.651 0.796 0.09885 0.846 0.236 3.03 -0.294 0.67 0.661 0.1797 0.746 0.201 2.77 -0.125 0.642 0.846 0.07284 0.883 0.251 3.1 PRS_PLINK_0.001 278.4 Abnormal weight gain Both 13 189 3 endocrine/metabolic brown 189, 13 48, 7 47, 1 47, 3 47, 2 -0.681 0.338 0.0436 1.361 0.506 0.261 0.981 -1.66 0.835 0.047 1.328 0.19 0.0371 0.978 -1.05 0.703 0.136 0.8668 0.35 0.0883 1.39 -1.53 0.869 0.0792 1.101 0.218 0.0396 1.19 PRS_PLINK_0.001 279 Disorders involving the immune mechanism Both 44 656 3 endocrine/metabolic brown 656, 44 164, 9 164, 10 164, 14 164, 11 0.167 0.153 0.276 0.5593 1.18 0.875 1.59 0.119 0.439 0.787 0.104 1.13 0.476 2.66 0.329 0.415 0.428 0.3682 1.39 0.616 3.14 0.1 0.44 0.82 0.08634 1.11 0.466 2.62 PRS_PLINK_0.001 279.1 Immunity deficiency Both 36 541 3 endocrine/metabolic brown 541, 36 136, 5 135, 9 135, 12 135, 10 0.256 0.172 0.137 0.8626 1.29 0.922 1.81 0.546 0.516 0.291 0.5368 1.73 0.627 4.75 0.755 0.502 0.133 0.8773 2.13 0.795 5.69 0.582 0.519 0.263 0.5804 1.79 0.646 4.95 PRS_PLINK_0.001 279.11 Deficiency of humoral immunity Both 27 371 3 endocrine/metabolic brown 371, 27 93, 3 93, 7 92, 8 93, 9 0.287 0.19 0.132 0.8806 1.33 0.918 1.93 0.719 0.614 0.241 0.6171 2.05 0.616 6.83 0.651 0.599 0.278 0.5564 1.92 0.592 6.21 0.677 0.611 0.268 0.5719 1.97 0.594 6.52 PRS_PLINK_0.001 279.7 Other immunological findings Both 63 628 3 endocrine/metabolic brown 628, 63 157, 15 157, 10 157, 18 157, 20 0.151 0.136 0.267 0.5736 1.16 0.891 1.52 -0.5 0.417 0.23 0.6378 0.607 0.268 1.37 0.239 0.363 0.511 0.2913 1.27 0.623 2.59 0.258 0.359 0.474 0.3245 1.29 0.64 2.62 PRS_PLINK_0.001 280 Iron deficiency anemias Both 1462 19527 4 hematopoietic darkorange1 19527, 1462 4881, 339 4882, 384 4881, 360 4882, 379 0.036 0.0274 0.19 0.7219 1.04 0.982 1.09 0.132 0.0772 0.0874 1.058 1.14 0.981 1.33 0.0629 0.0784 0.423 0.3741 1.06 0.913 1.24 0.137 0.0778 0.0783 1.106 1.15 0.985 1.34 PRS_PLINK_0.001 280.1 Iron deficiency anemias, unspecified or not due to blood loss Both 1384 18733 4 hematopoietic darkorange1 18733, 1384 4683, 323 4683, 361 4683, 342 4683, 358 0.0315 0.0282 0.263 0.5807 1.03 0.977 1.09 0.121 0.0793 0.128 0.8931 1.13 0.966 1.32 0.0618 0.0803 0.441 0.3551 1.06 0.909 1.25 0.131 0.0798 0.102 0.9931 1.14 0.975 1.33 PRS_PLINK_0.001 280.2 Iron deficiency anemia secondary to blood loss (chronic) Both 95 1207 4 hematopoietic darkorange1 1207, 95 302, 22 302, 24 301, 22 302, 27 0.124 0.107 0.248 0.6063 1.13 0.918 1.4 0.0817 0.3 0.786 0.1047 1.09 0.602 1.95 0.0231 0.304 0.939 0.02711 1.02 0.564 1.86 0.218 0.293 0.457 0.3402 1.24 0.7 2.21 PRS_PLINK_0.001 281 Other deficiency anemia Both 145 2750 4 hematopoietic darkorange1 2750, 145 688, 45 687, 34 687, 35 688, 31 -0.0864 0.082 0.292 0.5343 0.917 0.781 1.08 -0.286 0.231 0.216 0.6653 0.751 0.477 1.18 -0.226 0.229 0.322 0.4919 0.797 0.509 1.25 -0.356 0.237 0.133 0.8749 0.701 0.44 1.11 PRS_PLINK_0.001 281.1 Megaloblastic anemia Both 139 2650 4 hematopoietic darkorange1 2650, 139 663, 44 662, 30 662, 35 663, 30 -0.0887 0.0839 0.291 0.5368 0.915 0.776 1.08 -0.362 0.239 0.13 0.8854 0.696 0.436 1.11 -0.189 0.23 0.41 0.3873 0.827 0.527 1.3 -0.351 0.24 0.143 0.8436 0.704 0.44 1.13 PRS_PLINK_0.001 281.11 Pernicious anemia Both 98 1859 4 hematopoietic darkorange1 1859, 98 465, 30 465, 17 464, 28 465, 23 -0.00223 0.101 0.982 0.007711 0.998 0.818 1.22 -0.53 0.302 0.0792 1.101 0.589 0.326 1.06 -0.0173 0.267 0.948 0.02305 0.983 0.583 1.66 -0.266 0.28 0.342 0.4663 0.766 0.443 1.33 PRS_PLINK_0.001 281.12 Other vitamin B12 deficiency anemia Both 30 416 4 hematopoietic darkorange1 416, 30 104, 11 104, 10 104, 4 104, 5 -0.283 0.185 0.126 0.8994 0.753 0.524 1.08 -0.067 0.454 0.883 0.05418 0.935 0.384 2.28 -0.975 0.555 0.0791 1.102 0.377 0.127 1.12 -0.737 0.512 0.15 0.8246 0.479 0.176 1.3 PRS_PLINK_0.001 281.13 Folate-deficiency anemia Both 16 499 4 hematopoietic darkorange1 499, 16 125, 7 125, 1 124, 4 125, 4 -0.253 0.215 0.239 0.6218 0.777 0.51 1.18 -1.58 0.783 0.043 1.367 0.205 0.0442 0.951 -0.411 0.563 0.466 0.3314 0.663 0.22 2 -0.521 0.559 0.352 0.4536 0.594 0.198 1.78 PRS_PLINK_0.001 281.9 Deficiency anemias Both 6 131 4 hematopoietic darkorange1 131, 6 33, 2 33, 0 32, 3 33, 1 0.041 0.326 0.9 0.04589 1.04 0.55 1.97 -1.42 1.13 0.209 0.6789 0.241 0.026 2.23 0.0231 0.808 0.977 0.01 1.02 0.21 4.99 0.31 0.999 0.756 0.1212 1.36 0.192 9.66 PRS_PLINK_0.001 282 Hereditary hemolytic anemias Both 31 407 4 hematopoietic darkorange1 407, 31 102, 7 102, 14 101, 7 102, 3 -0.236 0.175 0.177 0.752 0.79 0.561 1.11 0.603 0.458 0.188 0.7258 1.83 0.745 4.49 0.014 0.518 0.979 0.009437 1.01 0.367 2.8 -0.845 0.623 0.175 0.7565 0.43 0.127 1.46 PRS_PLINK_0.001 282.8 Other hemoglobinopathies Both 14 168 4 hematopoietic darkorange1 168, 14 42, 2 42, 7 42, 4 42, 1 -0.185 0.246 0.452 0.3445 0.831 0.513 1.35 0.984 0.706 0.164 0.7865 2.67 0.67 10.7 0.518 0.772 0.502 0.2989 1.68 0.37 7.62 -0.564 0.881 0.523 0.2819 0.569 0.101 3.2 PRS_PLINK_0.001 282.9 Other hereditary hemolytic anemias Both 14 195 4 hematopoietic darkorange1 195, 14 49, 3 49, 6 48, 4 49, 1 -0.206 0.238 0.387 0.412 0.814 0.51 1.3 0.64 0.672 0.341 0.467 1.9 0.508 7.07 0.189 0.704 0.789 0.1032 1.21 0.304 4.8 -0.594 0.915 0.516 0.2874 0.552 0.0918 3.32 PRS_PLINK_0.001 283 Acquired hemolytic anemias Both 18 332 4 hematopoietic darkorange1 332, 18 83, 3 83, 3 83, 6 83, 6 0.343 0.231 0.138 0.8613 1.41 0.896 2.22 -0.128 0.684 0.851 0.06984 0.88 0.23 3.36 0.488 0.642 0.448 0.349 1.63 0.462 5.74 0.412 0.662 0.534 0.2724 1.51 0.412 5.52 PRS_PLINK_0.001 283.1 Autoimmune hemolytic anemias Both 13 255 4 hematopoietic darkorange1 255, 13 64, 1 64, 2 63, 5 64, 5 0.357 0.276 0.196 0.7076 1.43 0.832 2.45 0.0631 0.86 0.941 0.02618 1.07 0.197 5.75 1.04 0.825 0.209 0.6789 2.82 0.559 14.2 1.38 0.954 0.147 0.832 3.98 0.614 25.8 PRS_PLINK_0.001 284 Aplastic anemia Both 45 1069 4 hematopoietic darkorange1 1069, 45 268, 10 267, 16 267, 8 267, 11 0.0493 0.15 0.742 0.1297 1.05 0.784 1.41 0.365 0.392 0.352 0.4534 1.44 0.668 3.11 -0.195 0.443 0.659 0.1809 0.823 0.346 1.96 0.198 0.419 0.636 0.1965 1.22 0.536 2.77 PRS_PLINK_0.001 285 Other anemias Both 1943 30867 4 hematopoietic darkorange1 30867, 1943 7716, 513 7717, 473 7716, 507 7717, 450 -0.0453 0.0235 0.0541 1.267 0.956 0.913 1 -0.075 0.0658 0.254 0.5948 0.928 0.816 1.06 -0.00926 0.0647 0.886 0.05243 0.991 0.873 1.12 -0.122 0.0668 0.0689 1.162 0.886 0.777 1.01 PRS_PLINK_0.001 285.1 Acute posthemorrhagic anemia Both 51 693 4 hematopoietic darkorange1 693, 51 174, 5 173, 17 173, 17 173, 12 0.15 0.144 0.299 0.5238 1.16 0.876 1.54 1.2 0.481 0.0124 1.908 3.33 1.3 8.54 1.12 0.475 0.0186 1.731 3.06 1.21 7.76 0.878 0.5 0.0793 1.101 2.41 0.902 6.42 PRS_PLINK_0.001 285.2 Anemia of chronic disease Both 56 1743 4 hematopoietic darkorange1 1743, 56 436, 15 436, 11 435, 13 436, 17 0.0484 0.133 0.716 0.145 1.05 0.808 1.36 -0.3 0.381 0.43 0.3663 0.741 0.351 1.56 -0.179 0.367 0.626 0.2036 0.836 0.407 1.72 0.148 0.346 0.669 0.1745 1.16 0.588 2.29 PRS_PLINK_0.001 285.22 Anemia in neoplastic disease Both 28 1021 4 hematopoietic darkorange1 1021, 28 256, 6 255, 8 255, 6 255, 8 0.0906 0.181 0.617 0.2095 1.09 0.767 1.56 0.326 0.489 0.505 0.2968 1.39 0.531 3.62 -0.0686 0.515 0.894 0.04865 0.934 0.34 2.56 0.329 0.49 0.501 0.2997 1.39 0.532 3.63 PRS_PLINK_0.001 286 Coagulation defects Both 163 2380 4 hematopoietic darkorange1 2380, 163 595, 36 595, 47 595, 41 595, 39 -0.0222 0.0809 0.784 0.1059 0.978 0.835 1.15 0.292 0.226 0.197 0.7066 1.34 0.86 2.08 0.0909 0.233 0.697 0.1569 1.1 0.693 1.73 0.0463 0.236 0.845 0.07325 1.05 0.659 1.66 PRS_PLINK_0.001 286.1 Congenital coagulation defects Both 111 1218 4 hematopoietic darkorange1 1218, 111 305, 22 304, 38 304, 21 305, 30 0.0361 0.0985 0.714 0.1462 1.04 0.855 1.26 0.561 0.276 0.0424 1.372 1.75 1.02 3.01 -0.055 0.307 0.858 0.06659 0.947 0.519 1.73 0.298 0.287 0.299 0.5245 1.35 0.768 2.36 PRS_PLINK_0.001 286.11 Von willebrand's disease Both 25 263 4 hematopoietic darkorange1 263, 25 66, 4 66, 8 65, 6 66, 7 0.137 0.209 0.514 0.2894 1.15 0.761 1.73 0.621 0.623 0.319 0.4964 1.86 0.549 6.31 0.264 0.669 0.693 0.1593 1.3 0.351 4.83 0.205 0.634 0.746 0.1272 1.23 0.355 4.25 PRS_PLINK_0.001 286.12 Congenital deficiency of other clotting factors (including factor VII) Both 68 757 4 hematopoietic darkorange1 757, 68 190, 14 189, 23 189, 12 189, 19 0.051 0.124 0.682 0.1663 1.05 0.825 1.34 0.453 0.347 0.192 0.7176 1.57 0.797 3.1 -0.106 0.388 0.784 0.1055 0.899 0.42 1.92 0.347 0.353 0.325 0.4885 1.42 0.709 2.82 PRS_PLINK_0.001 286.13 Congenital factor VIII disorder Both 15 171 4 hematopoietic darkorange1 171, 15 43, 4 43, 6 42, 2 43, 3 -0.242 0.261 0.355 0.4503 0.785 0.471 1.31 0.194 0.649 0.765 0.1162 1.21 0.34 4.33 -0.372 0.959 0.698 0.1559 0.69 0.105 4.52 PRS_PLINK_0.001 286.5 Hemorrhagic disorder due to intrinsic circulating anticoagulants Both 13 205 4 hematopoietic darkorange1 205, 13 52, 6 51, 3 51, 3 51, 1 -0.463 0.248 0.0622 1.206 0.629 0.387 1.02 -0.138 0.699 0.844 0.07369 0.871 0.221 3.43 -0.255 0.707 0.718 0.144 0.775 0.194 3.09 -1.34 0.846 0.112 0.9507 0.261 0.0497 1.37 PRS_PLINK_0.001 286.7 Other and unspecified coagulation defects Both 53 976 4 hematopoietic darkorange1 976, 53 244, 14 244, 13 244, 15 244, 11 -0.146 0.136 0.285 0.5455 0.865 0.662 1.13 -0.0491 0.38 0.897 0.04722 0.952 0.452 2 0.11 0.372 0.768 0.1146 1.12 0.538 2.32 -0.28 0.398 0.482 0.3171 0.756 0.346 1.65 PRS_PLINK_0.001 287 Purpura and other hemorrhagic conditions Both 237 4182 4 hematopoietic darkorange1 4182, 237 1046, 54 1045, 55 1045, 63 1046, 65 0.0618 0.0657 0.347 0.4597 1.06 0.935 1.21 0.0124 0.194 0.949 0.02284 1.01 0.693 1.48 0.152 0.189 0.42 0.3765 1.16 0.804 1.69 0.163 0.188 0.386 0.413 1.18 0.814 1.7 PRS_PLINK_0.001 287.1 Spontaneous ecchymoses Both 21 319 4 hematopoietic darkorange1 319, 21 80, 8 80, 2 79, 5 80, 6 -0.126 0.21 0.548 0.2609 0.881 0.584 1.33 -1.23 0.691 0.0745 1.128 0.291 0.0752 1.13 -0.417 0.545 0.444 0.3522 0.659 0.226 1.92 -0.167 0.534 0.754 0.1225 0.846 0.297 2.41 PRS_PLINK_0.001 287.2 Allergic purpura Both 8 132 4 hematopoietic darkorange1 132, 8 33, 2 33, 2 33, 2 33, 2 -0.329 0.31 0.289 0.5391 0.72 0.392 1.32 0.153 0.842 0.856 0.0676 1.17 0.224 6.07 0.443 1.16 0.702 0.1535 1.56 0.161 15.1 0.564 0.927 0.543 0.2652 1.76 0.286 10.8 PRS_PLINK_0.001 287.3 Thrombocytopenia Both 221 3945 4 hematopoietic darkorange1 3945, 221 987, 51 986, 50 986, 60 986, 60 0.0648 0.0679 0.34 0.4686 1.07 0.934 1.22 -0.0193 0.201 0.924 0.03456 0.981 0.662 1.45 0.154 0.193 0.425 0.3713 1.17 0.799 1.7 0.143 0.194 0.46 0.337 1.15 0.789 1.69 PRS_PLINK_0.001 287.31 Primary thrombocytopenia Both 83 1072 4 hematopoietic darkorange1 1072, 83 268, 14 268, 23 268, 21 268, 25 0.138 0.11 0.21 0.677 1.15 0.925 1.42 0.473 0.335 0.158 0.8024 1.61 0.833 3.1 0.337 0.343 0.326 0.4871 1.4 0.715 2.74 0.541 0.332 0.104 0.9836 1.72 0.895 3.29 PRS_PLINK_0.001 287.32 Secondary thrombocytopenia Both 7 181 4 hematopoietic darkorange1 181, 7 46, 0 45, 2 45, 2 45, 3 0.473 0.347 0.173 0.7616 1.6 0.813 3.17 1.68 1.19 0.158 0.8008 5.37 0.52 55.4 1.04 1.01 0.303 0.5183 2.82 0.392 20.2 1.98 1.18 0.0932 1.031 7.26 0.718 73.4 PRS_PLINK_0.001 288 Diseases of white blood cells Both 546 9599 4 hematopoietic darkorange1 9599, 546 2400, 140 2400, 141 2399, 120 2400, 145 0.00812 0.0446 0.856 0.06775 1.01 0.924 1.1 0.00741 0.122 0.952 0.02154 1.01 0.793 1.28 -0.143 0.127 0.26 0.5844 0.867 0.675 1.11 0.0241 0.122 0.844 0.07386 1.02 0.807 1.3 PRS_PLINK_0.001 288.1 Decreased white blood cell count Both 446 8100 4 hematopoietic darkorange1 8100, 446 2025, 114 2025, 116 2025, 91 2025, 125 0.00573 0.0491 0.907 0.04234 1.01 0.913 1.11 0.0188 0.135 0.889 0.05118 1.02 0.782 1.33 -0.223 0.143 0.119 0.9248 0.8 0.604 1.06 0.0747 0.133 0.575 0.2405 1.08 0.83 1.4 PRS_PLINK_0.001 288.11 Neutropenia Both 447 8119 4 hematopoietic darkorange1 8119, 447 2030, 114 2030, 116 2029, 93 2030, 124 0.00569 0.049 0.908 0.04211 1.01 0.914 1.11 0.0179 0.135 0.894 0.04844 1.02 0.782 1.33 -0.201 0.142 0.158 0.801 0.818 0.619 1.08 0.0652 0.133 0.625 0.2043 1.07 0.822 1.39 PRS_PLINK_0.001 288.3 Eosinophilia Both 15 182 4 hematopoietic darkorange1 182, 15 46, 3 45, 2 45, 8 46, 2 0.0363 0.27 0.893 0.04914 1.04 0.611 1.76 -0.159 0.783 0.839 0.07621 0.853 0.184 3.96 1.02 0.694 0.14 0.8526 2.78 0.714 10.8 -0.426 0.765 0.577 0.2388 0.653 0.146 2.92 PRS_PLINK_0.001 289 Other diseases of blood and blood-forming organs Both 160 2225 4 hematopoietic darkorange1 2225, 160 557, 35 556, 38 556, 36 556, 51 0.161 0.0834 0.0539 1.268 1.17 0.997 1.38 0.0759 0.237 0.749 0.1256 1.08 0.678 1.72 0.0257 0.24 0.915 0.03862 1.03 0.641 1.64 0.379 0.224 0.0907 1.042 1.46 0.942 2.27 PRS_PLINK_0.001 289.3 Personal history of diseases of blood and blood-forming organs Both 51 805 4 hematopoietic darkorange1 805, 51 202, 14 201, 9 201, 12 201, 16 0.215 0.148 0.146 0.8367 1.24 0.928 1.66 -0.405 0.412 0.327 0.486 0.667 0.297 1.5 -0.124 0.387 0.748 0.1261 0.883 0.414 1.89 0.24 0.373 0.521 0.2835 1.27 0.612 2.64 PRS_PLINK_0.001 289.4 Lymphadenitis Both 409 6611 4 hematopoietic darkorange1 6611, 409 1653, 118 1653, 92 1652, 92 1653, 107 -0.0527 0.0504 0.296 0.5289 0.949 0.859 1.05 -0.234 0.142 0.101 0.9964 0.792 0.599 1.05 -0.237 0.143 0.0968 1.014 0.789 0.597 1.04 -0.104 0.138 0.451 0.3459 0.901 0.687 1.18 PRS_PLINK_0.001 289.5 Diseases of spleen Both 67 1269 4 hematopoietic darkorange1 1269, 67 318, 18 317, 18 317, 16 317, 15 -0.0365 0.119 0.759 0.1195 0.964 0.763 1.22 0.00894 0.328 0.978 0.009543 1.01 0.53 1.92 -0.128 0.338 0.705 0.1519 0.88 0.454 1.71 -0.234 0.344 0.498 0.3031 0.792 0.403 1.55 PRS_PLINK_0.001 289.8 Polycythemia, secondary Both 41 710 4 hematopoietic darkorange1 710, 41 178, 11 177, 7 177, 13 178, 10 0.025 0.158 0.874 0.0583 1.03 0.752 1.4 -0.453 0.464 0.329 0.483 0.636 0.256 1.58 0.12 0.407 0.768 0.1148 1.13 0.508 2.5 -0.127 0.433 0.77 0.1134 0.881 0.377 2.06 PRS_PLINK_0.001 289.9 Abnormality of red blood cells Both 14 240 4 hematopoietic darkorange1 240, 14 60, 3 60, 3 60, 4 60, 4 0.0686 0.258 0.79 0.1024 1.07 0.646 1.78 -0.224 0.788 0.776 0.11 0.799 0.171 3.74 0.652 0.728 0.371 0.4311 1.92 0.461 7.99 0.339 0.719 0.637 0.1959 1.4 0.343 5.75 PRS_PLINK_0.001 290 Delirium dementia and amnestic and other cognitive disorders Both 89 4335 5 mental disorders magenta 4335, 89 1084, 13 1084, 22 1083, 24 1084, 30 0.261 0.103 0.0115 1.939 1.3 1.06 1.59 0.574 0.335 0.0868 1.062 1.77 0.92 3.42 0.643 0.332 0.0529 1.276 1.9 0.992 3.65 0.809 0.322 0.012 1.922 2.25 1.2 4.22 PRS_PLINK_0.001 290.1 Dementias Both 30 2229 5 mental disorders magenta 2229, 30 558, 3 557, 7 557, 8 557, 12 0.314 0.173 0.0701 1.154 1.37 0.975 1.92 0.951 0.582 0.102 0.9904 2.59 0.827 8.09 1.01 0.582 0.0827 1.083 2.75 0.877 8.59 1.26 0.564 0.0256 1.593 3.52 1.17 10.6 PRS_PLINK_0.001 290.11 Alzheimer's disease Both 7 957 5 mental disorders magenta 957, 7 240, 0 239, 3 239, 1 239, 3 0.411 0.317 0.194 0.7122 1.51 0.811 2.81 2.15 1.13 0.0579 1.237 8.55 0.93 78.6 1.45 1.11 0.19 0.7223 4.28 0.487 37.7 1.46 1.07 0.171 0.7675 4.31 0.533 34.9 PRS_PLINK_0.001 290.16 Vascular dementia Both 5 442 5 mental disorders magenta 442, 5 111, 0 110, 1 110, 1 111, 3 0.651 0.381 0.0876 1.058 1.92 0.909 4.05 1.68 1.28 0.188 0.727 5.37 0.441 65.4 0.958 1.08 0.376 0.4244 2.61 0.312 21.8 1.58 1.14 0.165 0.7835 4.85 0.523 45 PRS_PLINK_0.001 290.2 Delirium due to conditions classified elsewhere Both 37 1510 5 mental disorders magenta 1510, 37 378, 6 377, 6 377, 12 378, 13 0.404 0.159 0.0111 1.954 1.5 1.1 2.05 0.0423 0.507 0.933 0.0299 1.04 0.386 2.82 0.712 0.462 0.123 0.9111 2.04 0.825 5.04 0.665 0.454 0.143 0.8444 1.94 0.799 4.73 PRS_PLINK_0.001 290.3 Other persistent mental disorders due to conditions classified elsewhere Both 7 158 5 mental disorders magenta 158, 7 40, 2 39, 2 39, 2 40, 1 -0.17 0.312 0.587 0.2316 0.844 0.458 1.56 0.0849 0.865 0.922 0.03535 1.09 0.2 5.93 -0.186 0.817 0.819 0.08648 0.83 0.167 4.11 -0.586 0.895 0.513 0.2901 0.557 0.0963 3.22 PRS_PLINK_0.001 291 Other specified nonpsychotic and/or transient mental disorders Both 101 2020 5 mental disorders magenta 2020, 101 505, 25 505, 28 505, 24 505, 24 -0.102 0.1 0.309 0.5096 0.903 0.743 1.1 0.117 0.275 0.669 0.1746 1.12 0.656 1.93 -0.00818 0.284 0.977 0.01008 0.992 0.568 1.73 0.0473 0.286 0.869 0.0612 1.05 0.599 1.84 PRS_PLINK_0.001 291.1 Transient mental disorders due to conditions classified elsewhere Both 20 320 5 mental disorders magenta 320, 20 80, 6 80, 5 80, 2 80, 7 0.138 0.223 0.536 0.2708 1.15 0.742 1.78 -0.0761 0.611 0.901 0.04532 0.927 0.28 3.07 -0.857 0.693 0.216 0.6654 0.424 0.109 1.65 0.173 0.555 0.755 0.122 1.19 0.401 3.53 PRS_PLINK_0.001 291.4 Specific nonpsychotic mental disorders due to brain damage Both 20 670 5 mental disorders magenta 670, 20 168, 6 167, 3 167, 9 168, 2 -0.184 0.212 0.386 0.4137 0.832 0.55 1.26 -0.508 0.607 0.402 0.3959 0.601 0.183 1.97 0.476 0.496 0.338 0.4715 1.61 0.608 4.26 -0.761 0.665 0.252 0.5983 0.467 0.127 1.72 PRS_PLINK_0.001 291.8 Alteration of consciousness Both 61 1066 5 mental disorders magenta 1066, 61 267, 16 266, 17 266, 14 267, 14 -0.166 0.127 0.192 0.7173 0.847 0.66 1.09 0.0659 0.346 0.849 0.07108 1.07 0.542 2.11 -0.132 0.359 0.713 0.1468 0.876 0.434 1.77 -0.0915 0.359 0.799 0.09758 0.913 0.452 1.84 PRS_PLINK_0.001 292 Neurological disorders Both 535 11443 5 mental disorders magenta 11443, 535 2861, 124 2861, 133 2860, 137 2861, 141 0.0219 0.0445 0.623 0.2057 1.02 0.937 1.12 0.0654 0.127 0.606 0.2174 1.07 0.833 1.37 0.105 0.126 0.406 0.3913 1.11 0.867 1.42 0.129 0.126 0.305 0.5158 1.14 0.889 1.46 PRS_PLINK_0.001 292.1 Aphasia/speech disturbance Both 188 3793 5 mental disorders magenta 3793, 188 949, 38 948, 51 948, 46 948, 53 0.0772 0.0753 0.305 0.5151 1.08 0.932 1.25 0.296 0.215 0.169 0.773 1.34 0.882 2.05 0.213 0.22 0.333 0.4779 1.24 0.804 1.91 0.348 0.214 0.105 0.9794 1.42 0.93 2.16 PRS_PLINK_0.001 292.2 Mild cognitive impairment Both 12 442 5 mental disorders magenta 442, 12 111, 5 110, 1 110, 5 111, 1 -0.357 0.249 0.152 0.8188 0.7 0.429 1.14 -1.12 0.789 0.156 0.8069 0.327 0.0696 1.53 0.0897 0.573 0.876 0.05762 1.09 0.355 3.37 -1.05 0.786 0.181 0.7414 0.35 0.075 1.63 PRS_PLINK_0.001 292.3 Memory loss Both 129 1786 5 mental disorders magenta 1786, 129 447, 27 446, 34 446, 30 447, 38 0.0971 0.0933 0.298 0.5254 1.1 0.918 1.32 0.214 0.26 0.411 0.3859 1.24 0.744 2.06 0.0207 0.269 0.939 0.02755 1.02 0.603 1.73 0.327 0.259 0.207 0.6834 1.39 0.834 2.31 PRS_PLINK_0.001 292.4 Altered mental status Both 204 5358 5 mental disorders magenta 5358, 204 1340, 57 1339, 41 1339, 59 1340, 47 -0.0572 0.071 0.421 0.3759 0.944 0.822 1.09 -0.336 0.205 0.101 0.9942 0.715 0.478 1.07 0.0602 0.188 0.749 0.1257 1.06 0.735 1.54 -0.198 0.199 0.319 0.4955 0.82 0.555 1.21 PRS_PLINK_0.001 292.6 Hallucinations Both 26 739 5 mental disorders magenta 739, 26 185, 5 185, 5 184, 9 185, 7 0.18 0.19 0.344 0.4636 1.2 0.825 1.74 -0.00174 0.554 0.997 0.001092 0.998 0.337 2.96 0.633 0.519 0.223 0.6525 1.88 0.681 5.21 0.3 0.524 0.567 0.2462 1.35 0.483 3.77 PRS_PLINK_0.001 293 Symptoms involving head and neck Both 451 5311 5 mental disorders magenta 5311, 451 1328, 108 1328, 125 1327, 117 1328, 101 -0.0456 0.049 0.352 0.4537 0.955 0.868 1.05 0.136 0.136 0.319 0.4956 1.15 0.877 1.5 0.0759 0.138 0.583 0.2341 1.08 0.823 1.41 -0.06 0.144 0.676 0.1699 0.942 0.711 1.25 PRS_PLINK_0.001 293.1 Swelling, mass, or lump in head and neck [Space-occupying lesion, intracranial NOS] Both 153 2267 5 mental disorders magenta 2267, 153 567, 42 567, 41 566, 32 567, 38 -0.041 0.0843 0.627 0.2028 0.96 0.814 1.13 -0.0227 0.224 0.919 0.03658 0.978 0.63 1.52 -0.277 0.239 0.246 0.6083 0.758 0.475 1.21 -0.106 0.229 0.643 0.1917 0.899 0.574 1.41 PRS_PLINK_0.001 295 Schizophrenia and other psychotic disorders Both 62 2187 5 mental disorders magenta 2187, 62 547, 12 547, 16 546, 15 547, 19 0.163 0.13 0.21 0.6776 1.18 0.912 1.52 0.299 0.366 0.413 0.3836 1.35 0.659 2.76 0.249 0.371 0.503 0.2986 1.28 0.62 2.65 0.511 0.362 0.158 0.8006 1.67 0.82 3.39 PRS_PLINK_0.001 295.1 Schizophrenia Both 40 1457 5 mental disorders magenta 1457, 40 365, 8 364, 10 364, 8 364, 14 0.192 0.16 0.229 0.6404 1.21 0.886 1.66 0.226 0.443 0.61 0.2148 1.25 0.526 2.98 -0.0805 0.462 0.862 0.0646 0.923 0.373 2.28 0.558 0.424 0.189 0.7237 1.75 0.76 4.01 PRS_PLINK_0.001 295.2 Paranoid disorders Both 11 455 5 mental disorders magenta 455, 11 114, 1 114, 4 113, 2 114, 4 0.381 0.282 0.176 0.7538 1.46 0.843 2.54 0.911 0.772 0.238 0.623 2.49 0.547 11.3 0.415 0.84 0.622 0.2064 1.51 0.292 7.86 1.35 0.807 0.0942 1.026 3.86 0.794 18.8 PRS_PLINK_0.001 295.3 Psychosis Both 19 473 5 mental disorders magenta 473, 19 119, 5 118, 2 118, 7 118, 5 0.234 0.245 0.339 0.4702 1.26 0.782 2.04 -0.923 0.72 0.2 0.6982 0.397 0.0968 1.63 0.307 0.551 0.577 0.2387 1.36 0.462 4 0.49 0.654 0.454 0.3426 1.63 0.452 5.88 PRS_PLINK_0.001 296 Mood disorders Both 1702 33167 5 mental disorders magenta 33167, 1702 8292, 417 8292, 438 8291, 430 8292, 417 0.00362 0.0249 0.884 0.05338 1 0.956 1.05 0.0582 0.0701 0.407 0.3908 1.06 0.924 1.22 0.0329 0.0706 0.641 0.193 1.03 0.9 1.19 0.000729 0.0712 0.992 0.003563 1 0.87 1.15 PRS_PLINK_0.001 296.1 Bipolar Both 116 2810 5 mental disorders magenta 2810, 116 703, 26 702, 33 702, 32 703, 25 -0.0231 0.094 0.806 0.0937 0.977 0.813 1.17 0.255 0.261 0.328 0.4844 1.29 0.774 2.15 0.237 0.264 0.368 0.4341 1.27 0.756 2.12 -0.0361 0.278 0.897 0.04737 0.965 0.559 1.66 PRS_PLINK_0.001 296.2 Depression Both 1619 31422 5 mental disorders magenta 31422, 1619 7856, 402 7855, 411 7855, 403 7856, 403 0.00664 0.0255 0.795 0.09981 1.01 0.958 1.06 0.0318 0.0719 0.658 0.1818 1.03 0.897 1.19 0.00301 0.0724 0.967 0.01465 1 0.87 1.16 0.000743 0.0725 0.992 0.003564 1 0.868 1.15 PRS_PLINK_0.001 296.22 Major depressive disorder Both 38 970 5 mental disorders magenta 970, 38 243, 10 242, 10 242, 10 243, 8 -0.0471 0.161 0.77 0.1133 0.954 0.695 1.31 -0.112 0.433 0.796 0.09925 0.894 0.382 2.09 0.0183 0.423 0.965 0.01525 1.02 0.444 2.34 -0.126 0.443 0.777 0.1098 0.882 0.37 2.1 PRS_PLINK_0.001 297.2 Suicide or self-inflicted injury Both 31 756 5 mental disorders magenta 756, 31 189, 7 189, 12 189, 5 189, 7 -0.0735 0.167 0.66 0.1802 0.929 0.669 1.29 0.491 0.452 0.277 0.5572 1.63 0.674 3.97 -0.295 0.529 0.577 0.2387 0.745 0.264 2.1 -0.00482 0.501 0.992 0.003344 0.995 0.373 2.66 PRS_PLINK_0.001 300 Anxiety disorders Both 978 18102 5 mental disorders magenta 18102, 978 4526, 247 4525, 240 4525, 258 4526, 233 -0.0293 0.0326 0.369 0.4329 0.971 0.911 1.04 -0.0296 0.0928 0.75 0.1248 0.971 0.809 1.16 0.0534 0.0915 0.56 0.2518 1.05 0.882 1.26 -0.0548 0.0938 0.559 0.2527 0.947 0.788 1.14 PRS_PLINK_0.001 300.1 Anxiety disorder Both 909 16771 5 mental disorders magenta 16771, 909 4193, 230 4193, 237 4192, 231 4193, 211 -0.0448 0.0337 0.184 0.7343 0.956 0.895 1.02 0.0277 0.0949 0.771 0.1131 1.03 0.854 1.24 0.00985 0.0957 0.918 0.03714 1.01 0.837 1.22 -0.0848 0.0979 0.387 0.4126 0.919 0.758 1.11 PRS_PLINK_0.001 300.11 Generalized anxiety disorder Both 22 410 5 mental disorders magenta 410, 22 103, 4 102, 4 102, 8 103, 6 0.153 0.207 0.459 0.3378 1.17 0.777 1.75 -0.0622 0.63 0.921 0.03558 0.94 0.273 3.23 0.672 0.558 0.228 0.6422 1.96 0.657 5.84 0.42 0.588 0.475 0.3229 1.52 0.481 4.82 PRS_PLINK_0.001 300.12 Agorophobia, social phobia, and panic disorder Both 96 1812 5 mental disorders magenta 1812, 96 453, 23 453, 19 453, 27 453, 27 0.107 0.107 0.319 0.496 1.11 0.902 1.37 -0.204 0.307 0.505 0.2963 0.815 0.447 1.49 0.114 0.284 0.687 0.1631 1.12 0.643 1.96 0.0954 0.285 0.738 0.1319 1.1 0.629 1.92 PRS_PLINK_0.001 300.13 Phobia Both 90 1290 5 mental disorders magenta 1290, 90 323, 23 322, 24 322, 22 323, 21 -0.0959 0.107 0.371 0.4304 0.909 0.736 1.12 0.0262 0.295 0.929 0.0319 1.03 0.576 1.83 -0.121 0.303 0.69 0.1615 0.886 0.49 1.6 -0.111 0.307 0.716 0.1449 0.895 0.491 1.63 PRS_PLINK_0.001 300.3 Obsessive-compulsive disorders Both 16 370 5 mental disorders magenta 370, 16 93, 7 92, 4 92, 0 93, 5 -0.312 0.235 0.183 0.7383 0.732 0.462 1.16 -0.728 0.591 0.218 0.6612 0.483 0.151 1.54 -2.85 1.25 0.0222 1.654 0.0579 0.00503 0.665 -0.543 0.581 0.35 0.4561 0.581 0.186 1.81 PRS_PLINK_0.001 300.4 Dysthymic disorder Both 10 154 5 mental disorders magenta 154, 10 39, 0 38, 3 38, 3 39, 4 0.507 0.315 0.108 0.9674 1.66 0.895 3.08 0.959 1.15 0.406 0.3913 2.61 0.272 25.1 1.43 1.23 0.244 0.6127 4.18 0.377 46.5 2.07 1.2 0.0848 1.072 7.93 0.753 83.5 PRS_PLINK_0.001 300.8 Acute reaction to stress Both 13 320 5 mental disorders magenta 320, 13 80, 3 80, 1 80, 3 80, 6 0.235 0.276 0.395 0.4033 1.26 0.736 2.17 -0.792 0.876 0.366 0.4365 0.453 0.0814 2.52 -0.174 0.698 0.803 0.09505 0.84 0.214 3.3 0.804 0.689 0.243 0.6141 2.24 0.579 8.63 PRS_PLINK_0.001 300.9 Posttraumatic stress disorder Both 12 306 5 mental disorders magenta 306, 12 77, 5 76, 1 76, 3 77, 3 -0.0727 0.272 0.789 0.1029 0.93 0.546 1.58 -1 0.807 0.214 0.6697 0.367 0.0753 1.78 -0.514 0.658 0.435 0.3618 0.598 0.165 2.17 -0.349 0.65 0.592 0.2279 0.706 0.197 2.52 PRS_PLINK_0.001 301 Personality disorders Both 26 888 5 mental disorders magenta 888, 26 222, 5 222, 3 222, 11 222, 7 0.378 0.191 0.0485 1.315 1.46 1 2.12 -0.291 0.607 0.631 0.1996 0.747 0.227 2.46 0.732 0.494 0.139 0.8584 2.08 0.789 5.47 0.399 0.527 0.449 0.3478 1.49 0.531 4.18 PRS_PLINK_0.001 301.2 Antisocial/borderline personality disorder Both 11 306 5 mental disorders magenta 306, 11 77, 2 76, 3 76, 3 77, 3 0.154 0.281 0.582 0.2351 1.17 0.673 2.02 0.357 0.765 0.64 0.1935 1.43 0.319 6.41 0.363 0.73 0.619 0.2083 1.44 0.344 6.01 0.279 0.74 0.706 0.1511 1.32 0.31 5.63 PRS_PLINK_0.001 302 Sexual and gender identity disorders Both 50 743 5 mental disorders magenta 743, 50 186, 15 186, 8 185, 14 186, 13 0.0687 0.144 0.634 0.1978 1.07 0.807 1.42 -0.666 0.421 0.113 0.9453 0.514 0.225 1.17 -0.0582 0.369 0.875 0.05817 0.943 0.458 1.94 -0.154 0.376 0.681 0.1667 0.857 0.41 1.79 PRS_PLINK_0.001 303 Psychogenic and somatoform disorders Both 87 1268 5 mental disorders magenta 1268, 87 317, 23 317, 24 317, 22 317, 18 -0.057 0.112 0.61 0.2148 0.945 0.759 1.18 0.0615 0.294 0.834 0.07878 1.06 0.598 1.89 -0.0354 0.3 0.906 0.04288 0.965 0.537 1.74 -0.258 0.314 0.412 0.3851 0.773 0.417 1.43 PRS_PLINK_0.001 303.3 Psychogenic disorder Both 71 947 5 mental disorders magenta 947, 71 237, 20 237, 23 236, 16 237, 12 -0.127 0.121 0.292 0.5346 0.88 0.695 1.12 0.124 0.314 0.692 0.1598 1.13 0.612 2.09 -0.221 0.334 0.508 0.2943 0.801 0.416 1.54 -0.432 0.362 0.233 0.6332 0.649 0.32 1.32 PRS_PLINK_0.001 303.4 Somatoform disorder Both 17 312 5 mental disorders magenta 312, 17 78, 5 78, 2 78, 6 78, 4 -0.00789 0.245 0.974 0.0113 0.992 0.614 1.6 -0.782 0.694 0.26 0.5844 0.458 0.117 1.79 0.283 0.588 0.63 0.2006 1.33 0.419 4.21 -0.465 0.646 0.472 0.3263 0.628 0.177 2.23 PRS_PLINK_0.001 304 Adjustment reaction Both 40 782 5 mental disorders magenta 782, 40 196, 10 195, 11 195, 11 196, 8 -0.0787 0.156 0.613 0.2127 0.924 0.681 1.25 0.0466 0.421 0.912 0.04012 1.05 0.459 2.39 0.0646 0.42 0.878 0.05665 1.07 0.468 2.43 -0.214 0.451 0.636 0.1968 0.808 0.334 1.95 PRS_PLINK_0.001 305.2 Eating disorder Both 14 276 5 mental disorders magenta 276, 14 69, 2 69, 7 69, 1 69, 4 -0.046 0.238 0.847 0.07213 0.955 0.599 1.52 1.09 0.691 0.116 0.9352 2.96 0.765 11.5 -0.28 0.849 0.741 0.1299 0.756 0.143 3.99 0.885 0.789 0.262 0.5817 2.42 0.516 11.4 PRS_PLINK_0.001 306 Other mental disorder Both 4746 60687 5 mental disorders magenta 60687, 4746 15172, 1138 15172, 1151 15171, 1196 15172, 1261 0.0389 0.0151 0.0102 1.991 1.04 1.01 1.07 0.00896 0.0435 0.837 0.07743 1.01 0.927 1.1 0.0548 0.0432 0.204 0.6893 1.06 0.971 1.15 0.101 0.0428 0.0178 1.75 1.11 1.02 1.2 PRS_PLINK_0.001 306.9 Tension headache Both 45 823 5 mental disorders magenta 823, 45 206, 11 206, 8 205, 17 206, 9 -0.0436 0.149 0.769 0.1139 0.957 0.715 1.28 -0.266 0.442 0.547 0.2619 0.766 0.322 1.82 0.376 0.381 0.323 0.4903 1.46 0.69 3.07 -0.204 0.431 0.636 0.1965 0.815 0.35 1.9 PRS_PLINK_0.001 313 Pervasive developmental disorders Both 8 213 5 mental disorders magenta 213, 8 54, 1 53, 3 53, 1 53, 3 0.136 0.328 0.678 0.1688 1.15 0.603 2.18 0.576 0.884 0.514 0.2887 1.78 0.315 10.1 0.106 0.894 0.905 0.04321 1.11 0.193 6.41 1.07 0.881 0.226 0.6463 2.91 0.517 16.3 PRS_PLINK_0.001 313.3 Autism Both 5 142 5 mental disorders magenta 142, 5 36, 1 35, 2 35, 0 36, 2 0.0624 0.435 0.886 0.05267 1.06 0.454 2.5 0.281 1 0.779 0.1086 1.32 0.186 9.41 -0.454 1.09 0.678 0.1688 0.635 0.0746 5.41 0.363 0.928 0.696 0.1576 1.44 0.233 8.86 PRS_PLINK_0.001 315 Develomental delays and disorders Both 19 891 5 mental disorders magenta 891, 19 223, 5 223, 4 222, 8 223, 2 -0.0883 0.202 0.662 0.1788 0.915 0.616 1.36 -0.224 0.574 0.696 0.1571 0.799 0.259 2.46 0.413 0.512 0.419 0.3778 1.51 0.555 4.12 -0.89 0.67 0.184 0.735 0.411 0.11 1.53 PRS_PLINK_0.001 315.1 Learning disorder Both 2 407 5 mental disorders magenta 407, 2 102, 0 102, 1 101, 1 102, 0 -0.379 0.425 0.372 0.4292 0.684 0.297 1.57 0.0128 1.1 0.991 0.004027 1.01 0.116 8.82 0.731 1.02 0.476 0.3228 2.08 0.279 15.5 -0.013 1.07 0.99 0.004249 0.987 0.121 8.02 PRS_PLINK_0.001 315.2 Speech and language disorder Both 5 228 5 mental disorders magenta 228, 5 57, 0 57, 1 57, 4 57, 0 0.324 0.357 0.364 0.4387 1.38 0.687 2.78 0.625 1.03 0.543 0.2653 1.87 0.249 14 2.7 1.28 0.0354 1.451 14.9 1.2 185 0.286 1.09 0.793 0.1006 1.33 0.157 11.3 PRS_PLINK_0.001 316 Substance addiction and disorders Both 374 13669 5 mental disorders magenta 13669, 374 3418, 69 3417, 90 3417, 108 3417, 107 0.16 0.0529 0.00252 2.598 1.17 1.06 1.3 0.268 0.16 0.0948 1.023 1.31 0.955 1.79 0.472 0.155 0.00233 2.632 1.6 1.18 2.17 0.465 0.156 0.00278 2.556 1.59 1.17 2.16 PRS_PLINK_0.001 316.1 Polyneuropathy due to drugs Both 8 171 5 mental disorders magenta 171, 8 43, 1 43, 4 42, 2 43, 1 0.0563 0.286 0.844 0.07359 1.06 0.604 1.85 2.7 1.43 0.06 1.222 14.9 0.893 247 0.656 0.953 0.492 0.3085 1.93 0.297 12.5 0.59 1.08 0.583 0.2341 1.8 0.219 14.8 PRS_PLINK_0.001 317 Alcohol-related disorders Both 1799 33088 5 mental disorders magenta 33088, 1799 8272, 346 8272, 403 8272, 503 8272, 547 0.183 0.0245 8.55e-14 13.07 1.2 1.14 1.26 0.148 0.0749 0.0488 1.311 1.16 1 1.34 0.371 0.0717 2.26e-07 6.645 1.45 1.26 1.67 0.462 0.0707 6.43e-11 10.19 1.59 1.38 1.82 PRS_PLINK_0.001 317.1 Alcoholism Both 1442 23249 5 mental disorders magenta 23249, 1442 5813, 280 5812, 312 5812, 399 5812, 451 0.198 0.0274 4.47e-13 12.35 1.22 1.16 1.29 0.0992 0.0843 0.239 0.6214 1.1 0.936 1.3 0.345 0.0802 1.67e-05 4.778 1.41 1.21 1.65 0.477 0.0785 1.26e-09 8.898 1.61 1.38 1.88 PRS_PLINK_0.001 317.11 Alcoholic liver damage Both 30 2220 5 mental disorders magenta 2220, 30 555, 5 555, 8 555, 6 555, 11 0.294 0.175 0.0917 1.038 1.34 0.953 1.89 0.401 0.502 0.424 0.3723 1.49 0.559 3.99 0.217 0.529 0.682 0.1663 1.24 0.441 3.5 0.74 0.482 0.125 0.9036 2.1 0.815 5.39 PRS_PLINK_0.001 318 Tobacco use disorder Both 2262 48409 5 mental disorders magenta 48409, 2262 12103, 500 12102, 539 12102, 581 12102, 642 0.106 0.0217 1.05e-06 5.979 1.11 1.07 1.16 0.0793 0.0634 0.211 0.6755 1.08 0.956 1.23 0.157 0.0625 0.0117 1.931 1.17 1.04 1.32 0.249 0.0613 4.89e-05 4.311 1.28 1.14 1.45 PRS_PLINK_0.001 320 Meningitis Both 94 1196 6 neurological darkblue 1196, 94 299, 21 299, 28 299, 26 299, 19 -0.039 0.109 0.72 0.143 0.962 0.777 1.19 0.373 0.296 0.208 0.682 1.45 0.812 2.6 0.304 0.304 0.316 0.5001 1.36 0.748 2.46 -0.098 0.32 0.76 0.1193 0.907 0.484 1.7 PRS_PLINK_0.001 323 Encephalitis Both 63 870 6 neurological darkblue 870, 63 218, 19 217, 15 217, 12 218, 17 -0.071 0.131 0.587 0.2317 0.931 0.721 1.2 -0.2 0.346 0.563 0.2491 0.819 0.416 1.61 -0.482 0.366 0.187 0.7276 0.617 0.302 1.26 -0.075 0.336 0.823 0.08455 0.928 0.481 1.79 PRS_PLINK_0.001 323.2 Acute (transverse) myelitis Both 24 196 6 neurological darkblue 196, 24 49, 5 49, 6 49, 7 49, 6 0.139 0.226 0.541 0.2669 1.15 0.737 1.79 0.119 0.604 0.843 0.07398 1.13 0.345 3.68 0.37 0.602 0.539 0.2685 1.45 0.445 4.71 0.179 0.593 0.763 0.1173 1.2 0.374 3.82 PRS_PLINK_0.001 324 Other CNS infection and poliomyelitis Both 48 712 6 neurological darkblue 712, 48 178, 9 178, 12 178, 12 178, 15 0.155 0.145 0.284 0.5463 1.17 0.879 1.55 0.224 0.43 0.602 0.2206 1.25 0.539 2.91 0.197 0.425 0.643 0.1921 1.22 0.53 2.8 0.479 0.409 0.242 0.6164 1.61 0.724 3.6 PRS_PLINK_0.001 327 Sleep disorders Both 250 2968 6 neurological darkblue 2968, 250 742, 60 742, 66 742, 64 742, 60 -0.0275 0.0674 0.684 0.1652 0.973 0.852 1.11 0.0658 0.185 0.722 0.1416 1.07 0.744 1.53 0.0244 0.186 0.896 0.0479 1.02 0.712 1.47 -0.0417 0.189 0.826 0.08319 0.959 0.662 1.39 PRS_PLINK_0.001 327.3 Sleep apnea Both 861 11373 6 neurological darkblue 11373, 861 2844, 202 2843, 235 2843, 242 2843, 182 -0.0395 0.0356 0.267 0.5734 0.961 0.896 1.03 0.156 0.0993 0.117 0.9327 1.17 0.962 1.42 0.187 0.099 0.0587 1.232 1.21 0.993 1.46 -0.0913 0.106 0.388 0.4106 0.913 0.742 1.12 PRS_PLINK_0.001 327.4 Insomnia Both 28 410 6 neurological darkblue 410, 28 103, 8 102, 9 102, 6 103, 5 -0.15 0.188 0.425 0.3715 0.86 0.595 1.24 -0.0871 0.5 0.862 0.06466 0.917 0.344 2.44 -0.472 0.532 0.374 0.4267 0.624 0.22 1.77 -0.438 0.558 0.432 0.3642 0.645 0.216 1.93 PRS_PLINK_0.001 327.41 Organic or persistent insomnia Both 24 345 6 neurological darkblue 345, 24 87, 6 86, 7 86, 6 86, 5 -0.0723 0.201 0.72 0.143 0.93 0.627 1.38 0.0768 0.553 0.89 0.05081 1.08 0.365 3.19 -0.144 0.561 0.797 0.09856 0.866 0.288 2.6 -0.104 0.58 0.858 0.0663 0.902 0.289 2.81 PRS_PLINK_0.001 331 Other cerebral degenerations Both 87 2876 6 neurological darkblue 2876, 87 719, 17 719, 23 719, 23 719, 24 0.101 0.107 0.347 0.4599 1.11 0.897 1.36 0.24 0.311 0.44 0.3565 1.27 0.691 2.34 0.375 0.313 0.231 0.6357 1.45 0.788 2.69 0.35 0.308 0.256 0.592 1.42 0.776 2.6 PRS_PLINK_0.001 331.1 Hydrocephalus Both 57 1264 6 neurological darkblue 1264, 57 316, 13 316, 17 316, 15 316, 12 -0.00325 0.137 0.981 0.0083 0.997 0.762 1.3 0.256 0.359 0.476 0.3227 1.29 0.639 2.61 0.204 0.378 0.589 0.2301 1.23 0.585 2.57 -0.00964 0.388 0.98 0.008698 0.99 0.463 2.12 PRS_PLINK_0.001 331.9 Cerebral degeneration, unspecified Both 16 1098 6 neurological darkblue 1098, 16 275, 2 274, 1 274, 5 275, 8 0.607 0.231 0.00855 2.068 1.84 1.17 2.89 -0.574 0.778 0.461 0.3367 0.563 0.123 2.59 0.72 0.666 0.279 0.554 2.06 0.557 7.58 1.17 0.634 0.066 1.18 3.21 0.926 11.1 PRS_PLINK_0.001 332 Parkinson's disease Both 112 2828 6 neurological darkblue 2828, 112 707, 23 707, 30 707, 31 707, 28 0.0739 0.0951 0.437 0.3597 1.08 0.894 1.3 0.243 0.277 0.381 0.4193 1.27 0.741 2.19 0.234 0.275 0.395 0.4029 1.26 0.737 2.17 0.0782 0.282 0.781 0.1072 1.08 0.623 1.88 PRS_PLINK_0.001 333 Extrapyramidal disease and abnormal movement disorders Both 127 2261 6 neurological darkblue 2261, 127 566, 24 565, 42 565, 27 565, 34 0.0823 0.0898 0.36 0.4441 1.09 0.91 1.29 0.543 0.259 0.0359 1.445 1.72 1.04 2.86 0.126 0.279 0.653 0.1849 1.13 0.656 1.96 0.324 0.269 0.228 0.6414 1.38 0.816 2.34 PRS_PLINK_0.001 333.1 Essential tremor Both 28 516 6 neurological darkblue 516, 28 129, 7 129, 10 129, 7 129, 4 -0.124 0.176 0.478 0.3202 0.883 0.626 1.25 0.322 0.472 0.495 0.305 1.38 0.547 3.48 0.104 0.514 0.839 0.07625 1.11 0.405 3.04 -0.454 0.566 0.422 0.3747 0.635 0.209 1.92 PRS_PLINK_0.001 333.2 Myoclonus Both 13 241 6 neurological darkblue 241, 13 61, 3 60, 4 60, 2 60, 4 0.0875 0.246 0.722 0.1413 1.09 0.673 1.77 0.42 0.814 0.606 0.2175 1.52 0.309 7.49 -0.368 0.82 0.653 0.185 0.692 0.139 3.45 0.261 0.82 0.75 0.1249 1.3 0.26 6.48 PRS_PLINK_0.001 333.4 Torsion dystonia Both 46 652 6 neurological darkblue 652, 46 163, 7 163, 18 163, 5 163, 16 0.0242 0.15 0.872 0.05971 1.02 0.764 1.37 0.856 0.435 0.0492 1.308 2.35 1 5.52 -0.272 0.524 0.603 0.2194 0.762 0.272 2.13 0.823 0.443 0.063 1.201 2.28 0.956 5.42 PRS_PLINK_0.001 334 Degenerative disease of the spinal cord Both 231 4553 6 neurological darkblue 4553, 231 1139, 40 1138, 73 1138, 63 1138, 55 0.0788 0.0676 0.244 0.6124 1.08 0.948 1.24 0.598 0.198 0.00256 2.592 1.82 1.23 2.68 0.442 0.203 0.0294 1.531 1.56 1.05 2.32 0.328 0.209 0.117 0.9321 1.39 0.921 2.09 PRS_PLINK_0.001 334.1 Spinocerebellar disease Both 15 291 6 neurological darkblue 291, 15 73, 0 73, 6 72, 7 73, 2 0.217 0.237 0.361 0.4425 1.24 0.78 1.98 2.41 1.16 0.0376 1.424 11.2 1.15 108 2.51 1.18 0.0334 1.477 12.3 1.22 123 1.7 1.11 0.124 0.9079 5.49 0.628 48 PRS_PLINK_0.001 334.2 Anterior horn cell disease Both 11 599 6 neurological darkblue 599, 11 150, 3 150, 4 149, 1 150, 3 0.0243 0.247 0.922 0.03536 1.02 0.631 1.66 0.2 0.633 0.752 0.1238 1.22 0.353 4.22 -0.685 0.801 0.392 0.4063 0.504 0.105 2.42 0.293 0.685 0.669 0.1745 1.34 0.35 5.13 PRS_PLINK_0.001 335 Multiple sclerosis Both 277 3617 6 neurological darkblue 3617, 277 905, 68 904, 72 904, 64 904, 73 0.0652 0.0622 0.295 0.5309 1.07 0.945 1.21 0.0577 0.174 0.74 0.1307 1.06 0.753 1.49 -0.0824 0.179 0.646 0.1897 0.921 0.648 1.31 0.0663 0.174 0.703 0.153 1.07 0.76 1.5 PRS_PLINK_0.001 337 Disorders of the autonomic nervous system Both 40 673 6 neurological darkblue 673, 40 169, 8 168, 10 168, 9 168, 13 0.0758 0.151 0.616 0.2101 1.08 0.802 1.45 0.231 0.449 0.606 0.2173 1.26 0.523 3.04 0.15 0.463 0.746 0.1273 1.16 0.469 2.88 0.4 0.435 0.358 0.4465 1.49 0.636 3.5 PRS_PLINK_0.001 337.1 Peripheral autonomic neuropathy Both 11 177 6 neurological darkblue 177, 11 45, 3 44, 2 44, 1 44, 5 0.258 0.275 0.349 0.4574 1.29 0.755 2.22 -0.746 0.885 0.399 0.399 0.474 0.0837 2.69 -2.16 1.19 0.07 1.155 0.115 0.0111 1.19 0.369 0.703 0.599 0.2224 1.45 0.365 5.73 PRS_PLINK_0.001 338 Pain Both 119 2052 6 neurological darkblue 2052, 119 513, 33 513, 31 513, 30 513, 25 -0.0384 0.0932 0.681 0.1671 0.962 0.802 1.16 -0.0312 0.253 0.902 0.04486 0.969 0.591 1.59 -0.0587 0.255 0.818 0.08749 0.943 0.573 1.55 -0.249 0.266 0.348 0.4579 0.779 0.463 1.31 PRS_PLINK_0.001 338.1 Acute pain Both 63 1039 6 neurological darkblue 1039, 63 260, 18 260, 14 259, 15 260, 16 -0.0428 0.123 0.729 0.1374 0.958 0.752 1.22 -0.151 0.357 0.672 0.1725 0.86 0.428 1.73 -0.13 0.348 0.707 0.1504 0.878 0.444 1.73 -0.128 0.343 0.709 0.1492 0.88 0.449 1.72 PRS_PLINK_0.001 338.2 Chronic pain Both 57 1019 6 neurological darkblue 1019, 57 255, 13 255, 21 254, 14 255, 9 -0.0648 0.137 0.635 0.197 0.937 0.717 1.22 0.466 0.348 0.181 0.7433 1.59 0.806 3.15 0.0514 0.375 0.891 0.05016 1.05 0.505 2.19 -0.337 0.411 0.413 0.3841 0.714 0.319 1.6 PRS_PLINK_0.001 339 Other headache syndromes Both 1321 20176 6 neurological darkblue 20176, 1321 5044, 351 5044, 303 5044, 352 5044, 315 -0.0325 0.0285 0.255 0.594 0.968 0.915 1.02 -0.144 0.0808 0.0745 1.128 0.866 0.739 1.01 0.0127 0.078 0.871 0.06011 1.01 0.869 1.18 -0.114 0.0804 0.157 0.803 0.893 0.762 1.04 PRS_PLINK_0.001 340 Migraine Both 564 7551 6 neurological darkblue 7551, 564 1888, 141 1888, 150 1887, 139 1888, 134 -0.0224 0.0434 0.605 0.2179 0.978 0.898 1.06 0.0717 0.121 0.555 0.256 1.07 0.847 1.36 0.00695 0.124 0.955 0.01993 1.01 0.79 1.28 -0.0426 0.125 0.732 0.1352 0.958 0.75 1.22 PRS_PLINK_0.001 340.1 Migrain with aura Both 45 568 6 neurological darkblue 568, 45 142, 9 142, 11 142, 11 142, 14 0.208 0.155 0.18 0.7451 1.23 0.909 1.67 0.208 0.437 0.633 0.1983 1.23 0.523 2.9 0.27 0.446 0.544 0.2642 1.31 0.547 3.14 0.526 0.43 0.222 0.6546 1.69 0.728 3.93 PRS_PLINK_0.001 341 Other demyelinating diseases of central nervous system Both 48 703 6 neurological darkblue 703, 48 176, 8 176, 11 175, 11 176, 18 0.216 0.145 0.137 0.8645 1.24 0.934 1.65 0.482 0.462 0.296 0.5286 1.62 0.655 4 0.344 0.457 0.452 0.3451 1.41 0.576 3.46 0.861 0.42 0.0404 1.394 2.37 1.04 5.39 PRS_PLINK_0.001 342 Hemiplegia Both 145 3801 6 neurological darkblue 3801, 145 951, 44 950, 32 950, 35 950, 34 -0.0939 0.084 0.264 0.579 0.91 0.772 1.07 -0.312 0.232 0.178 0.7485 0.732 0.464 1.15 -0.22 0.227 0.332 0.4791 0.802 0.514 1.25 -0.254 0.229 0.268 0.5716 0.776 0.495 1.22 PRS_PLINK_0.001 343 Infantile cerebral palsy Both 21 400 6 neurological darkblue 400, 21 100, 4 100, 5 100, 7 100, 5 0.225 0.202 0.266 0.5747 1.25 0.842 1.86 0.367 0.626 0.558 0.2535 1.44 0.423 4.92 0.775 0.6 0.196 0.7068 2.17 0.67 7.04 0.462 0.666 0.487 0.3124 1.59 0.431 5.85 PRS_PLINK_0.001 344 Other paralytic syndromes Both 103 1690 6 neurological darkblue 1690, 103 423, 29 422, 25 422, 21 423, 28 -0.0823 0.102 0.419 0.3782 0.921 0.754 1.12 -0.0749 0.276 0.786 0.1044 0.928 0.54 1.59 -0.28 0.287 0.331 0.4806 0.756 0.43 1.33 -0.0116 0.27 0.966 0.0152 0.988 0.582 1.68 PRS_PLINK_0.001 345 Epilepsy, recurrent seizures, convulsions Both 641 12673 6 neurological darkblue 12673, 641 3169, 157 3168, 167 3168, 153 3168, 164 -0.00862 0.04 0.829 0.08123 0.991 0.917 1.07 0.0576 0.114 0.612 0.2133 1.06 0.848 1.32 -0.0394 0.116 0.734 0.1343 0.961 0.766 1.21 0.0442 0.115 0.7 0.1546 1.05 0.835 1.31 PRS_PLINK_0.001 345.1 Epilepsy Both 93 2222 6 neurological darkblue 2222, 93 556, 24 555, 26 555, 21 556, 22 -0.109 0.101 0.281 0.5513 0.897 0.736 1.09 0.118 0.281 0.676 0.1703 1.12 0.648 1.95 -0.164 0.295 0.579 0.2375 0.849 0.476 1.51 -0.0873 0.293 0.766 0.1157 0.916 0.516 1.63 PRS_PLINK_0.001 345.11 Generalized convulsive epilepsy Both 39 1109 6 neurological darkblue 1109, 39 278, 13 277, 10 277, 8 277, 8 -0.226 0.146 0.122 0.9123 0.798 0.599 1.06 -0.293 0.402 0.466 0.3317 0.746 0.339 1.64 -0.455 0.421 0.28 0.5533 0.634 0.278 1.45 -0.463 0.424 0.275 0.5607 0.629 0.274 1.45 PRS_PLINK_0.001 345.12 Partial epilepsy Both 37 671 6 neurological darkblue 671, 37 168, 11 168, 7 167, 8 168, 11 -0.109 0.147 0.459 0.3383 0.897 0.672 1.2 -0.385 0.463 0.405 0.3927 0.68 0.275 1.68 -0.385 0.447 0.389 0.4099 0.68 0.283 1.63 -0.0195 0.423 0.963 0.01624 0.981 0.428 2.25 PRS_PLINK_0.001 345.3 Convulsions Both 225 5620 6 neurological darkblue 5620, 225 1405, 57 1405, 52 1405, 50 1405, 66 0.0222 0.0673 0.741 0.1302 1.02 0.896 1.17 -0.0852 0.193 0.66 0.1807 0.918 0.629 1.34 -0.143 0.195 0.464 0.3336 0.867 0.592 1.27 0.16 0.184 0.384 0.4153 1.17 0.818 1.68 PRS_PLINK_0.001 346.1 Nonspecific abnormal findings on radiological and other examination of skull and head Both 14 363 6 neurological darkblue 363, 14 91, 3 91, 2 90, 4 91, 5 0.256 0.251 0.309 0.5103 1.29 0.789 2.11 -0.262 0.709 0.712 0.1476 0.77 0.192 3.09 0.267 0.676 0.693 0.1591 1.31 0.347 4.91 0.345 0.646 0.593 0.2267 1.41 0.398 5.01 PRS_PLINK_0.001 348 Other conditions of brain Both 77 2104 6 neurological darkblue 2104, 77 526, 17 526, 17 526, 22 526, 21 0.176 0.118 0.137 0.864 1.19 0.946 1.5 0.00846 0.333 0.98 0.008901 1.01 0.525 1.94 0.275 0.316 0.384 0.4162 1.32 0.709 2.45 0.174 0.32 0.588 0.2309 1.19 0.635 2.23 PRS_PLINK_0.001 348.2 Cerebral edema and compression of brain Both 23 733 6 neurological darkblue 733, 23 184, 8 183, 5 183, 5 183, 5 -0.161 0.201 0.423 0.3735 0.851 0.573 1.26 -0.516 0.52 0.321 0.4936 0.597 0.215 1.65 -0.461 0.519 0.374 0.427 0.631 0.228 1.74 -0.528 0.538 0.326 0.4866 0.59 0.206 1.69 PRS_PLINK_0.001 348.4 Cerebral cysts Both 25 369 6 neurological darkblue 369, 25 93, 5 92, 8 92, 7 92, 5 0.062 0.202 0.759 0.12 1.06 0.716 1.58 0.303 0.551 0.583 0.2346 1.35 0.459 3.99 0.434 0.589 0.461 0.3362 1.54 0.487 4.9 -0.00975 0.591 0.987 0.005759 0.99 0.311 3.15 PRS_PLINK_0.001 348.7 Coma Both 48 853 6 neurological darkblue 853, 48 214, 9 213, 13 213, 11 213, 15 0.122 0.144 0.395 0.4034 1.13 0.853 1.5 0.313 0.413 0.448 0.3484 1.37 0.609 3.07 0.207 0.432 0.633 0.1989 1.23 0.527 2.87 0.468 0.413 0.257 0.5901 1.6 0.711 3.59 PRS_PLINK_0.001 348.8 Encephalopathy, not elsewhere classified Both 25 638 6 neurological darkblue 638, 25 160, 3 159, 3 159, 8 160, 11 0.644 0.213 0.0025 2.602 1.9 1.25 2.89 0.0314 0.665 0.962 0.01671 1.03 0.281 3.8 0.864 0.583 0.138 0.86 2.37 0.757 7.44 1.04 0.574 0.0714 1.147 2.82 0.914 8.68 PRS_PLINK_0.001 348.9 Other conditions of brain, NOS Both 36 1018 6 neurological darkblue 1018, 36 255, 8 254, 12 254, 10 255, 6 -0.087 0.163 0.594 0.2264 0.917 0.666 1.26 0.384 0.441 0.384 0.4153 1.47 0.618 3.49 0.255 0.443 0.566 0.2475 1.29 0.541 3.07 -0.343 0.49 0.484 0.3152 0.709 0.271 1.86 PRS_PLINK_0.001 349 Other and unspecified disorders of the nervous system Both 44 878 6 neurological darkblue 878, 44 220, 14 219, 11 219, 10 220, 9 -0.254 0.149 0.0884 1.054 0.776 0.579 1.04 -0.238 0.394 0.546 0.2632 0.788 0.364 1.71 -0.284 0.401 0.48 0.3191 0.753 0.343 1.65 -0.406 0.416 0.329 0.4834 0.666 0.295 1.5 PRS_PLINK_0.001 350 Abnormal movement Both 295 6552 6 neurological darkblue 6552, 295 1638, 73 1638, 83 1638, 79 1638, 60 -0.0599 0.0585 0.306 0.5141 0.942 0.84 1.06 0.146 0.163 0.369 0.4326 1.16 0.841 1.59 0.0833 0.165 0.614 0.212 1.09 0.787 1.5 -0.149 0.177 0.399 0.399 0.862 0.61 1.22 PRS_PLINK_0.001 350.1 Abnormal involuntary movements Both 118 2186 6 neurological darkblue 2186, 118 547, 31 546, 31 546, 35 547, 21 -0.112 0.092 0.222 0.6533 0.894 0.746 1.07 -0.0132 0.255 0.959 0.01829 0.987 0.599 1.63 0.125 0.249 0.615 0.2108 1.13 0.695 1.85 -0.345 0.283 0.224 0.6505 0.708 0.407 1.23 PRS_PLINK_0.001 350.2 Abnormality of gait Both 140 3851 6 neurological darkblue 3851, 140 963, 28 963, 47 962, 34 963, 31 -0.0186 0.0845 0.826 0.08295 0.982 0.832 1.16 0.518 0.238 0.0295 1.53 1.68 1.05 2.68 0.212 0.253 0.401 0.3969 1.24 0.753 2.03 0.15 0.26 0.565 0.248 1.16 0.698 1.93 PRS_PLINK_0.001 350.3 Lack of coordination Both 55 909 6 neurological darkblue 909, 55 228, 18 227, 11 227, 16 227, 10 -0.101 0.128 0.43 0.3665 0.904 0.703 1.16 -0.378 0.377 0.315 0.5014 0.685 0.327 1.43 -0.183 0.348 0.598 0.2234 0.832 0.421 1.65 -0.571 0.387 0.14 0.855 0.565 0.265 1.21 PRS_PLINK_0.001 350.6 Disturbances of sensation of smell and taste Both 7 149 6 neurological darkblue 149, 7 38, 3 37, 1 37, 1 37, 2 -0.195 0.35 0.578 0.2381 0.823 0.415 1.63 -0.746 0.884 0.398 0.3997 0.474 0.0839 2.68 -1.8 1.15 0.116 0.9343 0.165 0.0174 1.56 -0.592 0.869 0.496 0.3049 0.553 0.101 3.04 PRS_PLINK_0.001 351 Other peripheral nerve disorders Both 2469 32386 6 neurological darkblue 32386, 2469 8096, 639 8096, 645 8096, 567 8097, 618 -0.0199 0.021 0.341 0.4666 0.98 0.941 1.02 0.0142 0.058 0.807 0.09297 1.01 0.905 1.14 -0.12 0.0599 0.0449 1.348 0.887 0.789 0.997 -0.0336 0.0588 0.568 0.2456 0.967 0.862 1.09 PRS_PLINK_0.001 352 Disorders of other cranial nerves Both 242 3503 6 neurological darkblue 3503, 242 876, 59 876, 51 875, 64 876, 68 0.0324 0.0661 0.624 0.2048 1.03 0.907 1.18 -0.131 0.195 0.501 0.3 0.877 0.599 1.29 0.0651 0.187 0.727 0.1382 1.07 0.74 1.54 0.162 0.183 0.379 0.4218 1.18 0.82 1.68 PRS_PLINK_0.001 352.1 Trigeminal nerve disorders [CN5] Both 78 1169 6 neurological darkblue 1169, 78 293, 14 292, 17 292, 20 292, 27 0.222 0.116 0.055 1.26 1.25 0.995 1.57 0.216 0.354 0.541 0.2664 1.24 0.62 2.48 0.349 0.346 0.313 0.5047 1.42 0.72 2.79 0.671 0.33 0.0423 1.374 1.96 1.02 3.74 PRS_PLINK_0.001 352.2 Facial nerve disorders [CN7] Both 158 2253 6 neurological darkblue 2253, 158 564, 43 563, 32 563, 44 563, 39 -0.0373 0.0813 0.647 0.1894 0.963 0.822 1.13 -0.292 0.237 0.218 0.6607 0.747 0.469 1.19 -0.0256 0.222 0.908 0.04171 0.975 0.631 1.51 -0.128 0.227 0.573 0.2418 0.88 0.564 1.37 PRS_PLINK_0.001 353 Nerve root and plexus disorders Both 203 2857 6 neurological darkblue 2857, 203 715, 62 714, 41 714, 48 714, 52 -0.0375 0.0727 0.606 0.2176 0.963 0.835 1.11 -0.42 0.206 0.0414 1.383 0.657 0.438 0.984 -0.248 0.197 0.208 0.6816 0.78 0.53 1.15 -0.187 0.194 0.336 0.474 0.83 0.567 1.21 PRS_PLINK_0.001 353.1 Nerve plexus lesions Both 24 329 6 neurological darkblue 329, 24 83, 8 82, 5 82, 5 82, 6 0.00255 0.207 0.99 0.004281 1 0.668 1.51 -0.438 0.556 0.43 0.3663 0.645 0.217 1.92 -0.607 0.572 0.289 0.5396 0.545 0.177 1.67 -0.164 0.525 0.755 0.1223 0.849 0.303 2.37 PRS_PLINK_0.001 353.2 Nerve root lesions Both 8 134 6 neurological darkblue 134, 8 34, 3 33, 0 33, 1 34, 4 -0.19 0.307 0.536 0.2706 0.827 0.453 1.51 -1.46 1.11 0.186 0.7315 0.231 0.0264 2.02 -0.795 0.907 0.38 0.4197 0.452 0.0764 2.67 -0.00876 0.738 0.991 0.004134 0.991 0.233 4.21 PRS_PLINK_0.001 356 Hereditary and idiopathic peripheral neuropathy Both 32 387 6 neurological darkblue 387, 32 97, 10 97, 10 96, 7 97, 5 -0.225 0.172 0.193 0.7155 0.799 0.57 1.12 -0.127 0.459 0.783 0.1064 0.881 0.358 2.17 -0.293 0.499 0.557 0.2539 0.746 0.281 1.98 -0.45 0.558 0.42 0.3767 0.638 0.214 1.9 PRS_PLINK_0.001 357 Inflammatory and toxic neuropathy Both 221 3417 6 neurological darkblue 3417, 221 855, 56 854, 63 854, 49 854, 53 -0.0692 0.0693 0.319 0.4968 0.933 0.815 1.07 0.0783 0.189 0.678 0.1685 1.08 0.747 1.57 -0.127 0.199 0.522 0.2822 0.88 0.596 1.3 -0.0653 0.196 0.74 0.1309 0.937 0.638 1.38 PRS_PLINK_0.001 358 Myoneural disorders Both 31 515 6 neurological darkblue 515, 31 129, 9 129, 7 128, 8 129, 7 -0.036 0.169 0.831 0.08041 0.965 0.693 1.34 -0.357 0.483 0.46 0.3376 0.7 0.272 1.8 -0.218 0.469 0.643 0.1919 0.805 0.321 2.02 -0.326 0.486 0.503 0.2986 0.722 0.279 1.87 PRS_PLINK_0.001 358.1 Myasthenia gravis Both 29 464 6 neurological darkblue 464, 29 116, 9 116, 6 116, 7 116, 7 -0.0486 0.176 0.782 0.1066 0.953 0.675 1.34 -0.401 0.499 0.422 0.375 0.67 0.252 1.78 -0.348 0.49 0.477 0.3216 0.706 0.27 1.84 -0.261 0.486 0.591 0.2286 0.77 0.297 2 PRS_PLINK_0.001 359 Muscular dystrophies and other myopathies Both 73 1188 6 neurological darkblue 1188, 73 297, 19 297, 21 297, 19 297, 14 -0.0649 0.119 0.587 0.2315 0.937 0.742 1.18 0.0608 0.317 0.848 0.07157 1.06 0.571 1.98 0.0644 0.329 0.845 0.0731 1.07 0.559 2.03 -0.301 0.35 0.39 0.4089 0.74 0.373 1.47 PRS_PLINK_0.001 359.1 Muscular dystrophies Both 19 305 6 neurological darkblue 305, 19 77, 4 76, 4 76, 6 76, 5 0.0345 0.218 0.874 0.05829 1.04 0.675 1.59 0.0347 0.629 0.956 0.01952 1.04 0.302 3.55 0.361 0.617 0.558 0.2532 1.44 0.428 4.81 0.188 0.666 0.778 0.1088 1.21 0.327 4.45 PRS_PLINK_0.001 359.2 Myopathy Both 56 924 6 neurological darkblue 924, 56 231, 19 231, 14 231, 14 231, 9 -0.166 0.138 0.229 0.6397 0.847 0.646 1.11 -0.311 0.349 0.373 0.4279 0.733 0.369 1.45 -0.28 0.351 0.426 0.3711 0.756 0.38 1.5 -0.657 0.393 0.0945 1.024 0.518 0.24 1.12 PRS_PLINK_0.001 360 Disorders of the globe Both 98 878 7 sense organs darkseagreen4 878, 98 220, 27 219, 24 219, 22 220, 25 -0.0189 0.108 0.861 0.06486 0.981 0.793 1.21 -0.109 0.293 0.711 0.1482 0.897 0.505 1.59 -0.209 0.298 0.482 0.317 0.811 0.452 1.45 -0.0739 0.29 0.799 0.09761 0.929 0.526 1.64 PRS_PLINK_0.001 360.2 Progressive myopia Both 78 658 7 sense organs darkseagreen4 658, 78 165, 19 164, 22 164, 18 165, 19 0.0279 0.124 0.822 0.08539 1.03 0.807 1.31 0.121 0.326 0.71 0.1488 1.13 0.596 2.14 -0.069 0.341 0.84 0.07591 0.933 0.478 1.82 0.0297 0.34 0.93 0.03134 1.03 0.529 2.01 PRS_PLINK_0.001 361 Retinal detachments and defects Both 978 8452 7 sense organs darkseagreen4 8452, 978 2113, 242 2113, 237 2113, 252 2113, 247 0.00546 0.034 0.873 0.05916 1.01 0.941 1.07 -0.032 0.0963 0.74 0.1309 0.969 0.802 1.17 0.0433 0.0951 0.649 0.1877 1.04 0.867 1.26 0.0202 0.0957 0.833 0.07944 1.02 0.846 1.23 PRS_PLINK_0.001 361.1 Retinal detachment with retinal defect Both 421 3720 7 sense organs darkseagreen4 3720, 421 930, 102 930, 102 930, 107 930, 110 0.0185 0.0521 0.722 0.1412 1.02 0.92 1.13 -0.0134 0.147 0.928 0.03264 0.987 0.739 1.32 0.0388 0.146 0.79 0.1021 1.04 0.781 1.38 0.0615 0.145 0.672 0.1729 1.06 0.8 1.41 PRS_PLINK_0.001 361.2 Retinoschisis and retinal cysts Both 20 168 7 sense organs darkseagreen4 168, 20 42, 1 42, 10 42, 4 42, 5 0.141 0.236 0.549 0.2601 1.15 0.725 1.83 1.76 0.839 0.0361 1.442 5.79 1.12 30 1.25 0.923 0.174 0.7588 3.51 0.574 21.4 1.28 0.949 0.176 0.7533 3.6 0.562 23.1 PRS_PLINK_0.001 362 Other retinal disorders Both 782 9252 7 sense organs darkseagreen4 9252, 782 2313, 193 2313, 181 2313, 196 2313, 212 0.0378 0.0371 0.308 0.5113 1.04 0.966 1.12 -0.0576 0.107 0.592 0.2276 0.944 0.765 1.17 0.0315 0.106 0.766 0.1159 1.03 0.839 1.27 0.0898 0.104 0.389 0.4104 1.09 0.892 1.34 PRS_PLINK_0.001 362.2 Degeneration of macula and posterior pole of retina Both 447 5133 7 sense organs darkseagreen4 5133, 447 1284, 110 1283, 96 1283, 115 1283, 126 0.069 0.049 0.159 0.7986 1.07 0.973 1.18 -0.132 0.144 0.36 0.4436 0.876 0.66 1.16 0.0681 0.139 0.625 0.2044 1.07 0.815 1.41 0.139 0.136 0.308 0.5115 1.15 0.88 1.5 PRS_PLINK_0.001 362.29 Macular degeneration (senile) of retina NOS Both 445 5132 7 sense organs darkseagreen4 5132, 445 1283, 109 1283, 95 1283, 115 1283, 126 0.073 0.0491 0.137 0.8629 1.08 0.977 1.18 -0.133 0.145 0.361 0.4429 0.876 0.659 1.16 0.076 0.139 0.586 0.2322 1.08 0.821 1.42 0.148 0.137 0.279 0.5541 1.16 0.887 1.52 PRS_PLINK_0.001 362.3 Other nondiabetic retinopathy Both 47 394 7 sense organs darkseagreen4 394, 47 99, 14 98, 12 98, 8 99, 13 -0.149 0.138 0.28 0.5525 0.861 0.657 1.13 -0.121 0.417 0.773 0.112 0.886 0.391 2.01 -0.545 0.449 0.224 0.6493 0.58 0.241 1.4 -0.0238 0.409 0.954 0.02065 0.976 0.438 2.17 PRS_PLINK_0.001 362.31 Separation of retinal layers Both 27 226 7 sense organs darkseagreen4 226, 27 57, 7 56, 6 56, 5 57, 9 0.0427 0.187 0.819 0.08674 1.04 0.724 1.5 -0.15 0.564 0.79 0.1023 0.861 0.285 2.6 -0.424 0.583 0.466 0.3312 0.654 0.209 2.05 0.241 0.522 0.644 0.1913 1.27 0.458 3.54 PRS_PLINK_0.001 362.4 Retinal vascular changes and abnomalities Both 150 2032 7 sense organs darkseagreen4 2032, 150 508, 35 508, 38 508, 35 508, 42 0.0194 0.0828 0.814 0.08912 1.02 0.867 1.2 0.107 0.24 0.655 0.1837 1.11 0.696 1.78 0.00548 0.244 0.982 0.007859 1.01 0.624 1.62 0.145 0.235 0.537 0.2697 1.16 0.729 1.83 PRS_PLINK_0.001 362.6 Peripheral retinal degenerations Both 54 497 7 sense organs darkseagreen4 497, 54 125, 12 124, 8 124, 21 124, 13 0.192 0.137 0.16 0.7952 1.21 0.927 1.58 -0.334 0.45 0.458 0.3393 0.716 0.296 1.73 0.648 0.378 0.087 1.06 1.91 0.91 4.01 0.127 0.409 0.757 0.121 1.14 0.509 2.53 PRS_PLINK_0.001 362.7 Hereditary retinal dystrophies Both 16 208 7 sense organs darkseagreen4 208, 16 52, 7 52, 2 52, 3 52, 4 0.0891 0.248 0.719 0.1432 1.09 0.673 1.78 -1.19 0.733 0.104 0.9848 0.303 0.072 1.28 -0.574 0.639 0.369 0.4326 0.564 0.161 1.97 -0.348 0.615 0.572 0.2429 0.706 0.212 2.36 PRS_PLINK_0.001 362.8 Retinal hemorrhage/ischemia Both 23 300 7 sense organs darkseagreen4 300, 23 75, 2 75, 9 75, 5 75, 7 0.205 0.213 0.337 0.4726 1.23 0.808 1.87 1.26 0.701 0.0734 1.135 3.51 0.888 13.9 1.37 0.784 0.0795 1.099 3.95 0.851 18.4 1.22 0.704 0.0825 1.083 3.39 0.854 13.5 PRS_PLINK_0.001 363 Chorioretinal inflammations, scars, and other disorders of choroid Both 48 419 7 sense organs darkseagreen4 419, 48 105, 12 105, 17 104, 8 105, 11 0.0279 0.144 0.846 0.07241 1.03 0.775 1.36 0.343 0.393 0.383 0.417 1.41 0.652 3.05 -0.359 0.45 0.424 0.3722 0.698 0.289 1.69 -0.0694 0.427 0.871 0.0601 0.933 0.404 2.15 PRS_PLINK_0.001 363.3 Chorioretinal scars Both 18 176 7 sense organs darkseagreen4 176, 18 44, 4 44, 8 44, 3 44, 3 -0.1 0.23 0.663 0.1786 0.905 0.576 1.42 0.748 0.623 0.23 0.638 2.11 0.623 7.16 -0.158 0.691 0.819 0.08648 0.854 0.22 3.31 0.155 0.744 0.835 0.07828 1.17 0.272 5.02 PRS_PLINK_0.001 364 Corneal opacity and other disorders of cornea Both 141 1559 7 sense organs darkseagreen4 1559, 141 390, 35 390, 45 389, 25 390, 36 0.0235 0.0876 0.788 0.1034 1.02 0.862 1.22 0.238 0.233 0.308 0.5114 1.27 0.803 2 -0.305 0.265 0.25 0.6026 0.737 0.438 1.24 0.0254 0.245 0.917 0.03741 1.03 0.635 1.66 PRS_PLINK_0.001 364.1 Corneal opacity Both 13 225 7 sense organs darkseagreen4 225, 13 57, 0 56, 4 56, 5 56, 4 0.332 0.276 0.229 0.6408 1.39 0.812 2.39 1.92 1.22 0.116 0.9358 6.83 0.622 75 2.11 1.17 0.0724 1.141 8.25 0.826 82.4 1.92 1.17 0.101 0.9955 6.85 0.687 68.4 PRS_PLINK_0.001 364.2 Corneal edema Both 14 196 7 sense organs darkseagreen4 196, 14 49, 2 49, 5 49, 4 49, 3 0.228 0.336 0.498 0.3027 1.26 0.65 2.43 0.576 0.768 0.453 0.3442 1.78 0.395 8.01 0.315 0.763 0.679 0.168 1.37 0.307 6.11 0.529 0.816 0.517 0.2863 1.7 0.343 8.4 PRS_PLINK_0.001 364.4 Corneal degenerations Both 43 468 7 sense organs darkseagreen4 468, 43 117, 12 117, 14 117, 4 117, 13 0.0865 0.144 0.547 0.2617 1.09 0.823 1.45 0.0958 0.41 0.815 0.08877 1.1 0.493 2.46 -0.932 0.545 0.087 1.06 0.394 0.135 1.14 0.0739 0.406 0.856 0.06775 1.08 0.486 2.39 PRS_PLINK_0.001 364.41 Keratoconus Both 22 217 7 sense organs darkseagreen4 217, 22 55, 4 54, 10 54, 2 54, 6 0.0107 0.217 0.961 0.01748 1.01 0.661 1.55 1.02 0.677 0.131 0.8829 2.78 0.738 10.5 -0.67 0.743 0.367 0.4354 0.511 0.119 2.19 0.424 0.619 0.493 0.3068 1.53 0.454 5.14 PRS_PLINK_0.001 364.5 Corneal dystrophy Both 42 502 7 sense organs darkseagreen4 502, 42 126, 13 125, 6 125, 11 126, 12 0.0372 0.159 0.815 0.08896 1.04 0.76 1.42 -0.665 0.485 0.171 0.7674 0.514 0.199 1.33 -0.093 0.416 0.823 0.0846 0.911 0.404 2.06 -0.1 0.411 0.807 0.09316 0.904 0.404 2.02 PRS_PLINK_0.001 364.9 Cornea replaced by transplant Both 23 251 7 sense organs darkseagreen4 251, 23 63, 8 63, 5 62, 5 63, 5 -0.108 0.214 0.615 0.2113 0.898 0.59 1.37 -0.655 0.581 0.259 0.5859 0.52 0.166 1.62 -0.523 0.56 0.35 0.4562 0.593 0.198 1.77 -0.471 0.563 0.403 0.3949 0.625 0.207 1.88 PRS_PLINK_0.001 365 Glaucoma Both 937 10695 7 sense organs darkseagreen4 10695, 937 2674, 235 2674, 250 2673, 239 2674, 213 -0.0211 0.0343 0.539 0.2685 0.979 0.916 1.05 0.0545 0.0947 0.565 0.2481 1.06 0.877 1.27 0.0172 0.0958 0.858 0.06665 1.02 0.843 1.23 -0.0991 0.0988 0.316 0.5004 0.906 0.746 1.1 PRS_PLINK_0.001 365.1 Open-angle glaucoma Both 225 2541 7 sense organs darkseagreen4 2541, 225 636, 66 635, 72 635, 45 635, 42 -0.152 0.0686 0.027 1.568 0.859 0.751 0.983 0.0778 0.178 0.663 0.1788 1.08 0.762 1.53 -0.358 0.199 0.0725 1.139 0.699 0.473 1.03 -0.412 0.203 0.043 1.366 0.663 0.445 0.987 PRS_PLINK_0.001 365.11 Primary open angle glaucoma Both 223 2537 7 sense organs darkseagreen4 2537, 223 635, 67 634, 71 634, 44 634, 41 -0.168 0.069 0.0146 1.835 0.845 0.738 0.967 0.0486 0.178 0.785 0.1051 1.05 0.74 1.49 -0.394 0.2 0.0488 1.311 0.674 0.456 0.998 -0.452 0.204 0.0269 1.571 0.636 0.426 0.95 PRS_PLINK_0.001 365.2 Primary angle-closure glaucoma Both 133 1660 7 sense organs darkseagreen4 1660, 133 415, 31 415, 43 415, 28 415, 31 -0.00608 0.0901 0.946 0.02401 0.994 0.833 1.19 0.318 0.242 0.188 0.7259 1.37 0.856 2.21 -0.103 0.265 0.698 0.1562 0.902 0.537 1.52 -0.0268 0.262 0.918 0.03695 0.974 0.583 1.63 PRS_PLINK_0.001 366 Cataract Both 4187 42000 7 sense organs darkseagreen4 42000, 4187 10499, 972 10500, 1072 10500, 1064 10500, 1079 0.037 0.0163 0.0234 1.631 1.04 1.01 1.07 0.0924 0.0465 0.0467 1.331 1.1 1 1.2 0.0821 0.0466 0.0783 1.107 1.09 0.991 1.19 0.091 0.0466 0.0511 1.292 1.1 1 1.2 PRS_PLINK_0.001 366.1 Nonsenile Cataract Both 11 177 7 sense organs darkseagreen4 177, 11 45, 1 44, 3 44, 5 44, 2 0.123 0.286 0.666 0.1766 1.13 0.646 1.98 0.596 0.892 0.504 0.2976 1.81 0.316 10.4 1.2 0.854 0.159 0.7993 3.33 0.625 17.8 0.409 0.827 0.621 0.2066 1.5 0.297 7.61 PRS_PLINK_0.001 366.2 Senile cataract Both 1640 19278 7 sense organs darkseagreen4 19278, 1640 4819, 415 4819, 418 4819, 403 4820, 404 0.0104 0.0258 0.688 0.1626 1.01 0.961 1.06 0.00804 0.0722 0.911 0.04031 1.01 0.875 1.16 -0.0286 0.073 0.696 0.1577 0.972 0.842 1.12 -0.0246 0.0731 0.737 0.1327 0.976 0.846 1.13 PRS_PLINK_0.001 366.3 Traumatic cataract Both 19 213 7 sense organs darkseagreen4 213, 19 54, 5 53, 4 53, 5 53, 5 0.0778 0.233 0.739 0.1316 1.08 0.685 1.71 -0.171 0.623 0.784 0.1056 0.843 0.248 2.86 0.0561 0.6 0.926 0.03362 1.06 0.327 3.43 0.128 0.637 0.84 0.07554 1.14 0.326 3.97 PRS_PLINK_0.001 367 Disorders of refraction and accommodation; blindness and low vision Both 565 6073 7 sense organs darkseagreen4 6073, 565 1519, 141 1518, 130 1518, 147 1518, 147 0.0368 0.0438 0.401 0.3969 1.04 0.952 1.13 -0.0848 0.126 0.502 0.2989 0.919 0.717 1.18 0.0297 0.123 0.81 0.09173 1.03 0.809 1.31 0.016 0.123 0.897 0.04738 1.02 0.798 1.29 PRS_PLINK_0.001 367.1 Myopia Both 368 3204 7 sense organs darkseagreen4 3204, 368 801, 89 801, 81 801, 103 801, 95 0.0852 0.0548 0.12 0.9218 1.09 0.978 1.21 -0.0838 0.16 0.601 0.2209 0.92 0.671 1.26 0.133 0.152 0.382 0.4182 1.14 0.848 1.54 0.0415 0.156 0.79 0.1023 1.04 0.768 1.42 PRS_PLINK_0.001 367.2 Astigmatism Both 38 471 7 sense organs darkseagreen4 471, 38 118, 8 118, 11 117, 11 118, 8 0.0844 0.17 0.62 0.2078 1.09 0.78 1.52 0.377 0.459 0.412 0.3853 1.46 0.593 3.58 0.23 0.456 0.615 0.2111 1.26 0.514 3.08 0.169 0.503 0.736 0.1329 1.18 0.442 3.17 PRS_PLINK_0.001 367.8 Hypermetropia Both 59 590 7 sense organs darkseagreen4 590, 59 148, 19 147, 11 147, 11 148, 18 -0.0421 0.135 0.754 0.1224 0.959 0.736 1.25 -0.458 0.383 0.232 0.6339 0.633 0.299 1.34 -0.572 0.388 0.14 0.8527 0.564 0.264 1.21 -0.0674 0.341 0.843 0.07404 0.935 0.479 1.82 PRS_PLINK_0.001 367.9 Blindness and low vision Both 90 1796 7 sense organs darkseagreen4 1796, 90 449, 25 449, 24 449, 19 449, 22 -0.101 0.105 0.334 0.4768 0.904 0.736 1.11 -0.0596 0.284 0.834 0.07885 0.942 0.54 1.64 -0.282 0.301 0.349 0.4568 0.755 0.418 1.36 -0.159 0.29 0.583 0.2342 0.853 0.483 1.51 PRS_PLINK_0.001 368 Visual disturbances Both 545 7351 7 sense organs darkseagreen4 7351, 545 1838, 148 1838, 142 1837, 130 1838, 125 -0.0615 0.0444 0.166 0.7806 0.94 0.862 1.03 -0.0403 0.122 0.74 0.1307 0.96 0.757 1.22 -0.142 0.124 0.255 0.5942 0.868 0.68 1.11 -0.183 0.126 0.145 0.838 0.832 0.65 1.07 PRS_PLINK_0.001 368.1 Amblyopia Both 107 1187 7 sense organs darkseagreen4 1187, 107 297, 28 297, 27 296, 26 297, 26 0.0303 0.0992 0.76 0.119 1.03 0.849 1.25 0.0197 0.278 0.943 0.02532 1.02 0.592 1.76 -0.108 0.283 0.704 0.1523 0.898 0.515 1.56 -0.0245 0.282 0.931 0.03105 0.976 0.561 1.7 PRS_PLINK_0.001 368.2 Diplopia and disorders of binocular vision Both 154 1857 7 sense organs darkseagreen4 1857, 154 465, 50 464, 40 464, 34 464, 30 -0.177 0.0812 0.0297 1.527 0.838 0.715 0.983 -0.222 0.22 0.312 0.5053 0.801 0.521 1.23 -0.361 0.228 0.114 0.9431 0.697 0.446 1.09 -0.535 0.237 0.0239 1.621 0.586 0.368 0.932 PRS_PLINK_0.001 368.3 Anisometropia Both 45 374 7 sense organs darkseagreen4 374, 45 94, 11 93, 13 93, 9 94, 12 0.146 0.166 0.377 0.4232 1.16 0.836 1.6 0.27 0.427 0.527 0.2786 1.31 0.567 3.03 -0.202 0.454 0.656 0.183 0.817 0.336 1.99 0.068 0.443 0.878 0.05651 1.07 0.449 2.55 PRS_PLINK_0.001 368.4 Visual field defects Both 53 895 7 sense organs darkseagreen4 895, 53 224, 15 224, 15 223, 13 224, 10 -0.117 0.133 0.38 0.4198 0.89 0.686 1.15 0.118 0.367 0.748 0.1262 1.13 0.548 2.31 -0.0825 0.38 0.828 0.08183 0.921 0.437 1.94 -0.331 0.405 0.413 0.3836 0.718 0.325 1.59 PRS_PLINK_0.001 368.9 Subjective visual disturbances Both 84 1572 7 sense organs darkseagreen4 1572, 84 393, 20 393, 19 393, 20 393, 25 0.0589 0.113 0.601 0.2209 1.06 0.85 1.32 -0.0791 0.317 0.803 0.09523 0.924 0.496 1.72 -0.0559 0.313 0.858 0.06634 0.946 0.512 1.75 0.159 0.301 0.598 0.2235 1.17 0.65 2.12 PRS_PLINK_0.001 369 Infection of the eye Both 111 1426 7 sense organs darkseagreen4 1426, 111 357, 30 356, 28 356, 26 357, 27 0.0122 0.0978 0.9 0.04552 1.01 0.836 1.23 -0.0642 0.27 0.812 0.09059 0.938 0.553 1.59 -0.177 0.275 0.52 0.2843 0.838 0.489 1.44 -0.2 0.274 0.464 0.3337 0.818 0.479 1.4 PRS_PLINK_0.001 369.2 Eye infection, viral Both 25 325 7 sense organs darkseagreen4 325, 25 82, 3 81, 10 81, 7 81, 5 0.132 0.203 0.518 0.286 1.14 0.766 1.7 1.23 0.626 0.049 1.31 3.43 1.01 11.7 0.952 0.673 0.157 0.8028 2.59 0.692 9.69 0.72 0.693 0.299 0.5247 2.05 0.528 7.99 PRS_PLINK_0.001 369.5 Conjunctivitis, infectious Both 33 551 7 sense organs darkseagreen4 551, 33 138, 8 138, 6 137, 6 138, 13 0.112 0.176 0.525 0.2799 1.12 0.792 1.58 -0.228 0.51 0.655 0.184 0.796 0.293 2.16 -0.222 0.51 0.663 0.1783 0.801 0.295 2.18 0.394 0.442 0.373 0.4287 1.48 0.624 3.53 PRS_PLINK_0.001 370 Keratitis Both 55 700 7 sense organs darkseagreen4 700, 55 175, 15 175, 14 175, 11 175, 15 -0.0208 0.135 0.878 0.05666 0.979 0.751 1.28 -0.0462 0.376 0.902 0.04469 0.955 0.457 1.99 -0.364 0.398 0.36 0.4432 0.695 0.318 1.52 -0.00859 0.366 0.981 0.008211 0.991 0.484 2.03 PRS_PLINK_0.001 370.1 Corneal ulcer Both 29 335 7 sense organs darkseagreen4 335, 29 84, 7 84, 5 83, 9 84, 8 0.0772 0.186 0.678 0.169 1.08 0.751 1.55 -0.239 0.565 0.672 0.1724 0.788 0.26 2.38 0.181 0.504 0.719 0.1431 1.2 0.447 3.22 0.0234 0.521 0.964 0.01583 1.02 0.369 2.84 PRS_PLINK_0.001 371 Inflammation of the eye Both 704 7780 7 sense organs darkseagreen4 7780, 704 1945, 183 1945, 172 1945, 163 1945, 186 -0.016 0.0391 0.682 0.1662 0.984 0.912 1.06 -0.0652 0.111 0.556 0.2553 0.937 0.754 1.16 -0.115 0.112 0.306 0.5137 0.892 0.716 1.11 0.0177 0.109 0.871 0.05997 1.02 0.822 1.26 PRS_PLINK_0.001 371.1 Uveitis, noninfectious or NOS Both 107 1274 7 sense organs darkseagreen4 1274, 107 319, 33 318, 28 318, 27 319, 19 -0.171 0.097 0.0781 1.107 0.843 0.697 1.02 -0.136 0.265 0.607 0.2169 0.873 0.519 1.47 -0.205 0.265 0.44 0.357 0.815 0.485 1.37 -0.542 0.29 0.0619 1.208 0.582 0.329 1.03 PRS_PLINK_0.001 371.3 Inflammation of eyelids Both 551 5932 7 sense organs darkseagreen4 5932, 551 1483, 144 1483, 142 1483, 119 1483, 146 -0.0289 0.0441 0.512 0.2911 0.971 0.891 1.06 -0.0118 0.123 0.924 0.03432 0.988 0.776 1.26 -0.18 0.129 0.162 0.7898 0.835 0.649 1.08 0.0179 0.123 0.884 0.05343 1.02 0.8 1.3 PRS_PLINK_0.001 372 Disorders of conjunctiva Both 146 1900 7 sense organs darkseagreen4 1900, 146 475, 28 475, 35 475, 44 475, 39 0.0945 0.0864 0.274 0.5618 1.1 0.928 1.3 0.228 0.259 0.378 0.4221 1.26 0.756 2.09 0.527 0.25 0.0353 1.453 1.69 1.04 2.77 0.362 0.255 0.155 0.8094 1.44 0.872 2.37 PRS_PLINK_0.001 374 Other disorders of eyelids Both 1213 14169 7 sense organs darkseagreen4 14169, 1213 3543, 283 3542, 294 3542, 311 3542, 325 0.03 0.0301 0.319 0.4964 1.03 0.971 1.09 0.0349 0.0865 0.687 0.1633 1.04 0.874 1.23 0.0959 0.0855 0.262 0.5818 1.1 0.931 1.3 0.139 0.0849 0.102 0.9908 1.15 0.973 1.36 PRS_PLINK_0.001 374.1 Ectropion or entropion Both 201 2573 7 sense organs darkseagreen4 2573, 201 644, 56 643, 46 643, 40 643, 59 0.00699 0.0721 0.923 0.03492 1.01 0.874 1.16 -0.168 0.205 0.412 0.3847 0.845 0.566 1.26 -0.321 0.212 0.13 0.8873 0.725 0.479 1.1 0.0763 0.194 0.694 0.1589 1.08 0.738 1.58 PRS_PLINK_0.001 374.3 Ptosis of eyelid Both 389 4467 7 sense organs darkseagreen4 4467, 389 1117, 90 1117, 93 1116, 107 1117, 99 0.0114 0.0532 0.831 0.08046 1.01 0.911 1.12 0.0149 0.153 0.922 0.03508 1.02 0.752 1.37 0.164 0.149 0.27 0.5694 1.18 0.881 1.58 0.0909 0.151 0.547 0.2618 1.1 0.814 1.47 PRS_PLINK_0.001 375 Disorders of lacrimal system Both 478 5322 7 sense organs darkseagreen4 5322, 478 1331, 119 1330, 115 1330, 122 1331, 122 0.0319 0.0476 0.503 0.2987 1.03 0.94 1.13 -0.029 0.136 0.831 0.08024 0.971 0.744 1.27 0.0142 0.134 0.916 0.03814 1.01 0.78 1.32 0.0356 0.134 0.791 0.1018 1.04 0.796 1.35 PRS_PLINK_0.001 375.2 Epiphora Both 194 2145 7 sense organs darkseagreen4 2145, 194 537, 41 536, 50 536, 52 536, 51 0.122 0.0755 0.106 0.9762 1.13 0.975 1.31 0.216 0.217 0.32 0.495 1.24 0.811 1.9 0.241 0.215 0.262 0.5814 1.27 0.835 1.94 0.193 0.217 0.374 0.4266 1.21 0.793 1.85 PRS_PLINK_0.001 376 Disorders of the orbit Both 13 249 7 sense organs darkseagreen4 249, 13 63, 2 62, 4 62, 1 62, 6 0.1 0.268 0.708 0.1501 1.11 0.654 1.87 0.322 0.761 0.672 0.1727 1.38 0.311 6.13 -0.605 0.87 0.487 0.3124 0.546 0.0992 3.01 0.78 0.706 0.269 0.5702 2.18 0.547 8.7 PRS_PLINK_0.001 377 Disorders of optic nerve and visual pathways Both 65 921 7 sense organs darkseagreen4 921, 65 231, 18 230, 19 230, 14 230, 14 -0.151 0.13 0.244 0.6121 0.859 0.666 1.11 0.0549 0.331 0.868 0.06134 1.06 0.552 2.02 -0.265 0.354 0.454 0.3428 0.767 0.384 1.53 -0.272 0.358 0.446 0.3503 0.762 0.378 1.54 PRS_PLINK_0.001 377.1 Optic atrophy Both 11 141 7 sense organs darkseagreen4 141, 11 36, 4 35, 4 35, 1 35, 2 -0.189 0.3 0.529 0.2766 0.828 0.46 1.49 0.545 0.795 0.493 0.307 1.72 0.363 8.19 -1.43 0.937 0.127 0.8954 0.24 0.0382 1.5 -0.218 0.883 0.805 0.09402 0.805 0.143 4.54 PRS_PLINK_0.001 377.3 Optic neuritis/neuropathy Both 21 326 7 sense organs darkseagreen4 326, 21 82, 5 81, 7 81, 7 82, 2 -0.363 0.23 0.114 0.9435 0.696 0.443 1.09 0.396 0.563 0.482 0.3168 1.49 0.493 4.48 0.156 0.575 0.786 0.1045 1.17 0.379 3.6 -0.809 0.693 0.243 0.6144 0.445 0.114 1.73 PRS_PLINK_0.001 378 Strabismus and other disorders of binocular eye movements Both 288 3588 7 sense organs darkseagreen4 3588, 288 897, 80 897, 68 897, 63 897, 77 0.0396 0.0618 0.522 0.2826 1.04 0.922 1.17 -0.137 0.17 0.42 0.3772 0.872 0.624 1.22 -0.2 0.174 0.251 0.6 0.819 0.582 1.15 -0.0242 0.166 0.884 0.05358 0.976 0.705 1.35 PRS_PLINK_0.001 378.1 Strabismus (not specified as paralytic) Both 212 2312 7 sense organs darkseagreen4 2312, 212 578, 56 578, 54 578, 45 578, 57 0.0862 0.0717 0.229 0.64 1.09 0.947 1.25 -0.0273 0.198 0.89 0.0506 0.973 0.661 1.43 -0.191 0.207 0.355 0.4496 0.826 0.55 1.24 0.0122 0.195 0.95 0.02227 1.01 0.69 1.48 PRS_PLINK_0.001 378.2 Nystagmus and other irregular eye movements Both 43 550 7 sense organs darkseagreen4 550, 43 138, 13 137, 10 137, 13 138, 7 -0.235 0.156 0.133 0.8747 0.791 0.582 1.07 -0.277 0.416 0.506 0.2961 0.758 0.335 1.71 -0.0672 0.402 0.867 0.06187 0.935 0.425 2.06 -0.668 0.455 0.142 0.8474 0.513 0.21 1.25 PRS_PLINK_0.001 378.5 Paralytic strabismus Both 35 707 7 sense organs darkseagreen4 707, 35 177, 10 177, 7 176, 7 177, 11 0.171 0.177 0.334 0.4761 1.19 0.839 1.68 -0.391 0.468 0.404 0.3934 0.677 0.27 1.69 -0.325 0.463 0.483 0.3163 0.723 0.292 1.79 0.195 0.44 0.658 0.1817 1.21 0.513 2.88 PRS_PLINK_0.001 379 Other disorders of eye Both 813 8986 7 sense organs darkseagreen4 8986, 813 2247, 193 2246, 213 2246, 186 2247, 221 0.0386 0.037 0.296 0.5285 1.04 0.967 1.12 0.0976 0.104 0.346 0.4606 1.1 0.9 1.35 -0.0348 0.107 0.745 0.1278 0.966 0.783 1.19 0.14 0.103 0.176 0.7535 1.15 0.939 1.41 PRS_PLINK_0.001 379.2 Disorders of vitreous body Both 340 3446 7 sense organs darkseagreen4 3446, 340 862, 76 861, 87 861, 83 862, 94 0.0334 0.057 0.558 0.2534 1.03 0.925 1.16 0.139 0.163 0.395 0.4036 1.15 0.834 1.58 0.0851 0.165 0.607 0.217 1.09 0.788 1.51 0.223 0.162 0.169 0.7728 1.25 0.91 1.72 PRS_PLINK_0.001 379.3 Aphakia and other disorders of lens Both 359 4189 7 sense organs darkseagreen4 4189, 359 1048, 93 1047, 91 1047, 88 1047, 87 -0.0181 0.0548 0.741 0.1302 0.982 0.882 1.09 -0.0175 0.153 0.909 0.04155 0.983 0.728 1.33 -0.0452 0.154 0.769 0.1139 0.956 0.707 1.29 -0.0513 0.155 0.741 0.1304 0.95 0.701 1.29 PRS_PLINK_0.001 379.4 Anomalies of pupillary function Both 15 190 7 sense organs darkseagreen4 190, 15 48, 3 47, 4 47, 4 48, 4 0.16 0.272 0.557 0.2545 1.17 0.689 2 0.381 0.731 0.602 0.2202 1.46 0.349 6.13 0.373 0.708 0.599 0.2229 1.45 0.363 5.81 0.213 0.677 0.754 0.1228 1.24 0.328 4.66 PRS_PLINK_0.001 379.5 Disorders of iris and ciliary body Both 83 1023 7 sense organs darkseagreen4 1023, 83 256, 20 256, 19 255, 18 256, 26 0.144 0.118 0.22 0.6569 1.15 0.917 1.45 -0.106 0.322 0.741 0.13 0.899 0.478 1.69 -0.138 0.327 0.674 0.1715 0.871 0.459 1.65 0.231 0.304 0.446 0.3504 1.26 0.695 2.29 PRS_PLINK_0.001 379.9 Pain, swelling or discharge of eye Both 26 436 7 sense organs darkseagreen4 436, 26 109, 8 109, 3 109, 9 109, 6 -0.156 0.18 0.386 0.4135 0.856 0.602 1.22 -0.822 0.618 0.183 0.7364 0.439 0.131 1.48 0.175 0.488 0.72 0.1424 1.19 0.457 3.1 -0.164 0.516 0.751 0.1246 0.849 0.308 2.34 PRS_PLINK_0.001 380 Disorders of external ear Both 138 1556 7 sense organs darkseagreen4 1556, 138 389, 29 389, 30 389, 48 389, 31 0.0816 0.0912 0.371 0.431 1.09 0.908 1.3 0.0366 0.265 0.89 0.05051 1.04 0.617 1.74 0.448 0.244 0.067 1.174 1.56 0.969 2.53 0.0117 0.265 0.965 0.01563 1.01 0.602 1.7 PRS_PLINK_0.001 380.1 Otitis externa Both 102 1248 7 sense organs darkseagreen4 1248, 102 312, 24 312, 18 312, 29 312, 31 0.184 0.107 0.085 1.07 1.2 0.975 1.48 -0.259 0.312 0.407 0.39 0.772 0.419 1.42 0.196 0.283 0.49 0.3099 1.22 0.698 2.12 0.287 0.284 0.312 0.5061 1.33 0.764 2.32 PRS_PLINK_0.001 380.4 Impacted cerumen Both 80 951 7 sense organs darkseagreen4 951, 80 238, 20 238, 20 237, 13 238, 27 0.102 0.111 0.357 0.447 1.11 0.891 1.38 0.0468 0.321 0.884 0.0534 1.05 0.558 1.97 -0.328 0.355 0.355 0.4495 0.72 0.359 1.44 0.328 0.303 0.279 0.5539 1.39 0.766 2.51 PRS_PLINK_0.001 381 Otitis media and Eustachian tube disorders Both 410 5331 7 sense organs darkseagreen4 5331, 410 1333, 106 1333, 103 1332, 113 1333, 88 -0.0326 0.051 0.524 0.2811 0.968 0.876 1.07 -0.0169 0.143 0.906 0.04296 0.983 0.743 1.3 0.0555 0.141 0.693 0.1592 1.06 0.803 1.39 -0.205 0.149 0.17 0.7689 0.815 0.608 1.09 PRS_PLINK_0.001 381.1 Otitis media Both 331 4330 7 sense organs darkseagreen4 4330, 331 1083, 79 1082, 87 1082, 92 1083, 73 -0.0112 0.057 0.845 0.07324 0.989 0.884 1.11 0.108 0.16 0.499 0.3018 1.11 0.814 1.53 0.155 0.159 0.328 0.4838 1.17 0.856 1.59 -0.0816 0.167 0.625 0.2039 0.922 0.664 1.28 PRS_PLINK_0.001 381.11 Suppurative and unspecified otitis media Both 141 2138 7 sense organs darkseagreen4 2138, 141 535, 43 534, 33 534, 35 535, 30 -0.0914 0.0878 0.298 0.5259 0.913 0.768 1.08 -0.241 0.236 0.305 0.5153 0.785 0.495 1.25 -0.199 0.233 0.393 0.4054 0.819 0.519 1.29 -0.325 0.241 0.178 0.7505 0.723 0.45 1.16 PRS_PLINK_0.001 381.2 Eustachian tube disorders Both 38 496 7 sense organs darkseagreen4 496, 38 124, 15 124, 5 124, 9 124, 9 -0.0761 0.164 0.643 0.1918 0.927 0.672 1.28 -1.03 0.489 0.0358 1.446 0.359 0.138 0.934 -0.416 0.425 0.328 0.484 0.66 0.287 1.52 -0.489 0.426 0.251 0.5996 0.613 0.266 1.41 PRS_PLINK_0.001 381.3 Mastoiditis & related conditions Both 32 414 7 sense organs darkseagreen4 414, 32 104, 2 103, 12 103, 14 104, 4 0.213 0.185 0.249 0.6033 1.24 0.861 1.78 1.89 0.687 0.00592 2.227 6.63 1.72 25.5 2.36 0.749 0.00158 2.801 10.6 2.45 46.1 0.837 0.793 0.291 0.5358 2.31 0.488 10.9 PRS_PLINK_0.001 381.9 Otorrhea Both 55 726 7 sense organs darkseagreen4 726, 55 182, 16 181, 14 181, 12 182, 13 -0.0963 0.13 0.458 0.3394 0.908 0.704 1.17 -0.0738 0.364 0.839 0.07599 0.929 0.455 1.9 -0.326 0.382 0.394 0.4045 0.722 0.342 1.53 -0.334 0.379 0.379 0.4219 0.716 0.341 1.51 PRS_PLINK_0.001 382 Otalgia Both 69 784 7 sense organs darkseagreen4 784, 69 196, 16 196, 18 196, 20 196, 15 -0.0452 0.125 0.718 0.1438 0.956 0.748 1.22 0.0703 0.347 0.839 0.07602 1.07 0.543 2.12 0.201 0.341 0.557 0.2545 1.22 0.626 2.38 -0.0149 0.361 0.967 0.01449 0.985 0.485 2 PRS_PLINK_0.001 383 Otosclerosis Both 94 749 7 sense organs darkseagreen4 749, 94 188, 26 187, 19 187, 28 187, 21 -0.0539 0.109 0.621 0.2067 0.948 0.765 1.17 -0.298 0.312 0.339 0.4693 0.742 0.403 1.37 0.0999 0.288 0.728 0.1377 1.11 0.629 1.94 -0.189 0.309 0.54 0.2677 0.828 0.452 1.52 PRS_PLINK_0.001 384 Other disorders of tympanic membrane Both 237 3348 7 sense organs darkseagreen4 3348, 237 837, 57 837, 62 837, 55 837, 63 -0.0102 0.0663 0.877 0.05685 0.99 0.869 1.13 0.0832 0.188 0.658 0.182 1.09 0.752 1.57 -0.0455 0.194 0.814 0.08914 0.956 0.653 1.4 0.106 0.188 0.574 0.241 1.11 0.769 1.61 PRS_PLINK_0.001 384.4 Perforation of tympanic membrane Both 179 2640 7 sense organs darkseagreen4 2640, 179 660, 37 660, 51 660, 42 660, 49 0.0363 0.0759 0.633 0.1985 1.04 0.894 1.2 0.303 0.22 0.168 0.7742 1.35 0.88 2.08 0.156 0.23 0.497 0.3035 1.17 0.745 1.83 0.289 0.222 0.194 0.7117 1.33 0.863 2.06 PRS_PLINK_0.001 385 Other disorders of middle ear and mastoid Both 159 2033 7 sense organs darkseagreen4 2033, 159 509, 38 508, 38 508, 50 508, 33 -0.0298 0.0816 0.715 0.146 0.971 0.827 1.14 -0.0242 0.234 0.918 0.0373 0.976 0.617 1.54 0.25 0.222 0.261 0.584 1.28 0.831 1.98 -0.196 0.244 0.421 0.3756 0.822 0.509 1.33 PRS_PLINK_0.001 385.3 Cholesteatoma Both 126 1589 7 sense organs darkseagreen4 1589, 126 398, 34 397, 31 397, 37 397, 24 -0.108 0.0911 0.237 0.6245 0.898 0.751 1.07 -0.151 0.254 0.552 0.258 0.86 0.523 1.41 0.0288 0.246 0.907 0.04263 1.03 0.636 1.67 -0.448 0.273 0.1 0.9981 0.639 0.374 1.09 PRS_PLINK_0.001 385.5 Tympanosclerosis and middle ear disease related to otitis media Both 34 596 7 sense organs darkseagreen4 596, 34 149, 5 149, 8 149, 12 149, 9 0.176 0.175 0.315 0.5022 1.19 0.846 1.68 0.393 0.547 0.472 0.3257 1.48 0.507 4.33 0.714 0.503 0.156 0.8071 2.04 0.762 5.47 0.605 0.538 0.261 0.5831 1.83 0.638 5.25 PRS_PLINK_0.001 386 Vertiginous syndromes and other disorders of vestibular system Both 352 4420 7 sense organs darkseagreen4 4420, 352 1105, 87 1105, 99 1105, 80 1105, 86 -0.0116 0.0545 0.831 0.08025 0.988 0.888 1.1 0.127 0.152 0.406 0.3918 1.14 0.842 1.53 -0.0806 0.16 0.614 0.2116 0.923 0.674 1.26 -0.0107 0.158 0.946 0.02415 0.989 0.726 1.35 PRS_PLINK_0.001 386.1 Meniere's disease Both 126 1465 7 sense organs darkseagreen4 1465, 126 367, 25 366, 31 366, 36 366, 34 0.164 0.0925 0.0771 1.113 1.18 0.982 1.41 0.203 0.274 0.458 0.3395 1.23 0.716 2.1 0.383 0.267 0.151 0.8219 1.47 0.87 2.47 0.284 0.271 0.294 0.5311 1.33 0.781 2.26 PRS_PLINK_0.001 386.2 Peripheral or central vertigo Both 72 944 7 sense organs darkseagreen4 944, 72 236, 17 236, 21 236, 12 236, 22 0.0778 0.115 0.497 0.3036 1.08 0.864 1.35 0.243 0.329 0.46 0.3377 1.28 0.669 2.43 -0.339 0.372 0.362 0.4412 0.712 0.343 1.48 0.268 0.326 0.41 0.3872 1.31 0.691 2.48 PRS_PLINK_0.001 386.3 Labyrinthitis Both 144 1966 7 sense organs darkseagreen4 1966, 144 492, 43 491, 40 491, 31 492, 30 -0.194 0.0846 0.0215 1.667 0.823 0.698 0.972 -0.0741 0.225 0.742 0.1295 0.929 0.597 1.44 -0.344 0.24 0.152 0.8193 0.709 0.443 1.13 -0.362 0.242 0.135 0.8702 0.696 0.434 1.12 PRS_PLINK_0.001 386.9 Dizziness and giddiness (Light-headedness and vertigo) Both 775 11412 7 sense organs darkseagreen4 11412, 775 2853, 197 2853, 201 2853, 189 2853, 188 -0.0179 0.0372 0.631 0.2 0.982 0.913 1.06 0.0255 0.103 0.805 0.09416 1.03 0.838 1.26 -0.0283 0.105 0.788 0.1037 0.972 0.791 1.19 -0.0385 0.106 0.716 0.1452 0.962 0.782 1.18 PRS_PLINK_0.001 388 Other disorders of ear Both 34 489 7 sense organs darkseagreen4 489, 34 123, 7 122, 9 122, 9 122, 9 0.0262 0.166 0.874 0.05826 1.03 0.742 1.42 0.198 0.483 0.681 0.1669 1.22 0.474 3.14 0.328 0.489 0.502 0.2989 1.39 0.532 3.62 0.226 0.486 0.642 0.1924 1.25 0.484 3.25 PRS_PLINK_0.001 389 Hearing loss Both 829 10404 7 sense organs darkseagreen4 10404, 829 2601, 225 2601, 190 2601, 200 2601, 214 -0.0269 0.0361 0.455 0.342 0.973 0.907 1.04 -0.165 0.102 0.105 0.9772 0.848 0.694 1.04 -0.121 0.101 0.231 0.6372 0.886 0.726 1.08 -0.05 0.0998 0.616 0.2103 0.951 0.782 1.16 PRS_PLINK_0.001 389.1 Sensorineural hearing loss Both 88 1160 7 sense organs darkseagreen4 1160, 88 290, 19 290, 19 290, 27 290, 23 0.0532 0.107 0.62 0.2076 1.05 0.855 1.3 -0.0243 0.325 0.94 0.02671 0.976 0.516 1.85 0.369 0.306 0.227 0.6434 1.45 0.795 2.63 0.219 0.315 0.487 0.3125 1.25 0.671 2.31 PRS_PLINK_0.001 389.2 Conductive hearing loss Both 109 1170 7 sense organs darkseagreen4 1170, 109 293, 23 292, 23 292, 31 293, 32 0.172 0.0974 0.0775 1.111 1.19 0.981 1.44 -0.0496 0.299 0.868 0.06127 0.952 0.529 1.71 0.312 0.282 0.268 0.5721 1.37 0.786 2.38 0.356 0.28 0.205 0.6885 1.43 0.824 2.47 PRS_PLINK_0.001 389.4 Tinnitus Both 106 1291 7 sense organs darkseagreen4 1291, 106 323, 22 323, 29 322, 25 323, 30 0.108 0.102 0.289 0.5391 1.11 0.912 1.36 0.293 0.286 0.306 0.5148 1.34 0.765 2.35 0.131 0.296 0.659 0.1814 1.14 0.638 2.04 0.313 0.284 0.271 0.5677 1.37 0.784 2.39 PRS_PLINK_0.001 394 Rheumatic disease of the heart valves Both 837 11851 8 circulatory system red 11851, 837 2963, 200 2963, 231 2962, 203 2963, 203 0.00507 0.0353 0.886 0.05275 1.01 0.938 1.08 0.142 0.0998 0.154 0.8138 1.15 0.948 1.4 0.0185 0.103 0.857 0.06684 1.02 0.832 1.25 0.0169 0.103 0.87 0.06052 1.02 0.831 1.25 PRS_PLINK_0.001 394.2 Mitral valve disease Both 548 7204 8 circulatory system red 7204, 548 1801, 127 1801, 152 1801, 132 1801, 137 0.0225 0.0436 0.606 0.2173 1.02 0.939 1.11 0.177 0.124 0.155 0.8108 1.19 0.935 1.52 0.0507 0.129 0.694 0.1587 1.05 0.817 1.35 0.067 0.128 0.6 0.2219 1.07 0.832 1.37 PRS_PLINK_0.001 394.3 Aortic valve disease Both 208 3087 8 circulatory system red 3087, 208 772, 52 772, 54 771, 48 772, 54 0.0136 0.0709 0.848 0.07169 1.01 0.882 1.16 0.0386 0.198 0.845 0.07289 1.04 0.705 1.53 -0.0843 0.204 0.679 0.168 0.919 0.616 1.37 0.0517 0.2 0.796 0.09886 1.05 0.711 1.56 PRS_PLINK_0.001 394.7 Disease of tricuspid valve Both 150 2551 8 circulatory system red 2551, 150 638, 29 638, 44 637, 32 638, 45 0.0863 0.0815 0.29 0.538 1.09 0.929 1.28 0.414 0.241 0.0853 1.069 1.51 0.944 2.43 0.0782 0.257 0.761 0.1186 1.08 0.653 1.79 0.394 0.241 0.103 0.9884 1.48 0.924 2.38 PRS_PLINK_0.001 395 Heart valve disorders Both 728 10153 8 circulatory system red 10153, 728 2539, 173 2538, 201 2538, 181 2538, 173 -0.00519 0.0379 0.891 0.05018 0.995 0.924 1.07 0.148 0.107 0.169 0.7732 1.16 0.939 1.43 0.0564 0.11 0.608 0.216 1.06 0.853 1.31 -0.00117 0.111 0.992 0.003661 0.999 0.803 1.24 PRS_PLINK_0.001 395.1 Nonrheumatic mitral valve disorders Both 525 6968 8 circulatory system red 6968, 525 1742, 123 1742, 139 1742, 128 1742, 135 0.0316 0.0444 0.476 0.322 1.03 0.946 1.13 0.122 0.128 0.339 0.4698 1.13 0.88 1.45 0.0502 0.131 0.701 0.1541 1.05 0.814 1.36 0.0809 0.129 0.531 0.2745 1.08 0.841 1.4 PRS_PLINK_0.001 395.2 Nonrheumatic aortic valve disorders Both 37 647 8 circulatory system red 647, 37 162, 11 162, 7 161, 8 162, 11 0.0584 0.161 0.716 0.1452 1.06 0.774 1.45 -0.431 0.46 0.348 0.458 0.65 0.264 1.6 -0.296 0.442 0.503 0.2984 0.744 0.313 1.77 -0.0327 0.425 0.939 0.0275 0.968 0.421 2.23 PRS_PLINK_0.001 395.3 Nonrheumatic tricuspid valve disorders Both 18 264 8 circulatory system red 264, 18 66, 6 66, 6 66, 3 66, 3 -0.261 0.228 0.252 0.5993 0.77 0.492 1.2 0.237 0.567 0.676 0.1699 1.27 0.417 3.85 -0.596 0.67 0.373 0.428 0.551 0.148 2.05 -0.479 0.646 0.459 0.3386 0.619 0.174 2.2 PRS_PLINK_0.001 395.4 Nonrheumatic pulmonary valve disorders Both 11 215 8 circulatory system red 215, 11 54, 1 54, 5 53, 1 54, 4 0.211 0.263 0.423 0.3739 1.24 0.737 2.07 1.1 0.795 0.167 0.7779 3 0.632 14.3 -0.248 0.943 0.792 0.1011 0.78 0.123 4.95 0.801 0.816 0.327 0.486 2.23 0.45 11 PRS_PLINK_0.001 395.6 Heart valve replaced Both 235 3630 8 circulatory system red 3630, 235 908, 58 907, 66 907, 58 908, 53 -0.0487 0.0677 0.472 0.3257 0.953 0.834 1.09 0.139 0.185 0.45 0.3466 1.15 0.801 1.65 0.0171 0.19 0.928 0.03233 1.02 0.701 1.48 -0.0822 0.195 0.674 0.1713 0.921 0.628 1.35 PRS_PLINK_0.001 396 Abnormal heart sounds Both 207 2592 8 circulatory system red 2592, 207 648, 49 648, 63 648, 45 648, 50 -0.0287 0.0717 0.689 0.162 0.972 0.844 1.12 0.233 0.197 0.235 0.6285 1.26 0.859 1.86 -0.0796 0.211 0.706 0.1512 0.924 0.611 1.4 0.0094 0.207 0.964 0.01602 1.01 0.673 1.51 PRS_PLINK_0.001 401 Hypertension Both 13018 73723 8 circulatory system red 73723, 13018 18430, 3163 18431, 3244 18430, 3247 18431, 3364 0.0156 0.00979 0.111 0.9544 1.02 0.996 1.04 0.0176 0.0278 0.525 0.2795 1.02 0.964 1.07 0.0136 0.0279 0.625 0.2042 1.01 0.96 1.07 0.043 0.0277 0.121 0.9185 1.04 0.989 1.1 PRS_PLINK_0.001 401.1 Essential hypertension Both 12994 73671 8 circulatory system red 73671, 12994 18417, 3151 18418, 3236 18417, 3245 18418, 3362 0.0168 0.0098 0.0865 1.063 1.02 0.998 1.04 0.0188 0.0278 0.499 0.302 1.02 0.965 1.08 0.0166 0.0279 0.551 0.2585 1.02 0.963 1.07 0.0458 0.0277 0.0986 1.006 1.05 0.991 1.11 PRS_PLINK_0.001 401.2 Hypertensive heart and/or renal disease Both 197 4977 8 circulatory system red 4977, 197 1245, 58 1244, 48 1244, 51 1244, 40 -0.102 0.0732 0.164 0.7852 0.903 0.783 1.04 -0.174 0.196 0.375 0.4259 0.84 0.572 1.23 -0.135 0.194 0.486 0.3135 0.874 0.598 1.28 -0.373 0.207 0.0725 1.14 0.689 0.459 1.03 PRS_PLINK_0.001 401.21 Hypertensive heart disease Both 28 945 8 circulatory system red 945, 28 237, 5 236, 11 236, 3 236, 9 0.0218 0.192 0.909 0.04127 1.02 0.702 1.49 0.601 0.501 0.231 0.6372 1.82 0.683 4.87 -0.665 0.634 0.295 0.5306 0.514 0.148 1.78 0.328 0.542 0.546 0.2629 1.39 0.479 4.02 PRS_PLINK_0.001 401.22 Hypertensive chronic kidney disease Both 170 4069 8 circulatory system red 4069, 170 1018, 53 1017, 39 1017, 46 1017, 32 -0.139 0.0786 0.0768 1.115 0.87 0.746 1.02 -0.301 0.211 0.155 0.8089 0.74 0.489 1.12 -0.139 0.203 0.494 0.3063 0.87 0.584 1.3 -0.524 0.225 0.0199 1.7 0.592 0.381 0.921 PRS_PLINK_0.001 401.3 Other hypertensive complications Both 17 381 8 circulatory system red 381, 17 96, 3 95, 3 95, 7 95, 4 0.145 0.244 0.551 0.2585 1.16 0.717 1.87 0.0574 0.682 0.933 0.03012 1.06 0.278 4.03 0.787 0.62 0.204 0.6899 2.2 0.652 7.41 0.432 0.67 0.519 0.2848 1.54 0.414 5.73 PRS_PLINK_0.001 402 Elevated blood pressure reading without diagnosis of hypertension Both 263 4064 8 circulatory system red 4064, 263 1016, 79 1016, 57 1016, 60 1016, 67 -0.0607 0.064 0.343 0.4648 0.941 0.83 1.07 -0.333 0.178 0.0617 1.209 0.717 0.506 1.02 -0.285 0.176 0.105 0.9797 0.752 0.533 1.06 -0.188 0.171 0.272 0.566 0.828 0.592 1.16 PRS_PLINK_0.001 411 Ischemic Heart Disease Both 5135 54675 8 circulatory system red 54675, 5135 13669, 1230 13669, 1365 13668, 1244 13669, 1296 0.00937 0.0147 0.525 0.2799 1.01 0.981 1.04 0.104 0.0414 0.0119 1.924 1.11 1.02 1.2 0.0147 0.0424 0.729 0.1375 1.01 0.934 1.1 0.0525 0.0421 0.212 0.6728 1.05 0.97 1.14 PRS_PLINK_0.001 411.1 Unstable angina (intermediate coronary syndrome) Both 787 13216 8 circulatory system red 13216, 787 3304, 192 3304, 214 3304, 191 3304, 190 0.00662 0.0368 0.857 0.06681 1.01 0.937 1.08 0.119 0.102 0.243 0.6147 1.13 0.922 1.38 0.00737 0.105 0.944 0.025 1.01 0.82 1.24 0.00441 0.105 0.967 0.01476 1 0.817 1.23 PRS_PLINK_0.001 411.2 Myocardial infarction Both 1807 29110 8 circulatory system red 29110, 1807 7278, 415 7277, 465 7277, 472 7278, 455 0.0353 0.0243 0.146 0.8346 1.04 0.988 1.09 0.114 0.0695 0.101 0.9953 1.12 0.978 1.28 0.132 0.0694 0.0577 1.239 1.14 0.996 1.31 0.0895 0.0702 0.202 0.6936 1.09 0.953 1.25 PRS_PLINK_0.001 411.3 Angina pectoris Both 2406 36889 8 circulatory system red 36889, 2406 9223, 568 9222, 660 9222, 588 9222, 590 0.00923 0.0211 0.662 0.1791 1.01 0.968 1.05 0.152 0.0591 0.0103 1.988 1.16 1.04 1.31 0.0407 0.0608 0.503 0.2982 1.04 0.925 1.17 0.044 0.061 0.471 0.3273 1.04 0.927 1.18 PRS_PLINK_0.001 411.4 Coronary atherosclerosis Both 3489 40271 8 circulatory system red 40271, 3489 10068, 838 10068, 928 10067, 854 10068, 869 0.00668 0.0178 0.707 0.1507 1.01 0.972 1.04 0.098 0.0499 0.0496 1.304 1.1 1 1.22 0.0191 0.0509 0.708 0.15 1.02 0.922 1.13 0.0369 0.0509 0.469 0.329 1.04 0.939 1.15 PRS_PLINK_0.001 411.41 Aneurysm and dissection of heart Both 166 1779 8 circulatory system red 1779, 166 445, 36 445, 40 444, 43 445, 47 0.141 0.0785 0.0735 1.134 1.15 0.987 1.34 0.104 0.236 0.659 0.1814 1.11 0.699 1.76 0.262 0.236 0.267 0.5729 1.3 0.818 2.07 0.317 0.23 0.169 0.7726 1.37 0.874 2.16 PRS_PLINK_0.001 411.8 Other chronic ischemic heart disease, unspecified Both 2047 33936 8 circulatory system red 33936, 2047 8484, 513 8484, 524 8484, 500 8484, 510 -0.00175 0.0228 0.939 0.02744 0.998 0.955 1.04 0.0213 0.064 0.74 0.131 1.02 0.901 1.16 -0.0263 0.0649 0.685 0.1643 0.974 0.858 1.11 -0.00419 0.0648 0.948 0.02301 0.996 0.877 1.13 PRS_PLINK_0.001 411.9 Other acute and subacute forms of ischemic heart disease Both 170 3116 8 circulatory system red 3116, 170 779, 39 779, 48 779, 46 779, 37 0.0319 0.0769 0.679 0.1683 1.03 0.888 1.2 0.223 0.218 0.307 0.5124 1.25 0.815 1.92 0.156 0.22 0.477 0.3217 1.17 0.76 1.8 0.00502 0.232 0.983 0.007551 1.01 0.637 1.58 PRS_PLINK_0.001 414 Other forms of chronic heart disease Both 246 4591 8 circulatory system red 4591, 246 1148, 58 1148, 59 1147, 64 1148, 65 0.0611 0.0656 0.351 0.4545 1.06 0.935 1.21 0.0186 0.187 0.92 0.03599 1.02 0.707 1.47 0.103 0.184 0.573 0.2416 1.11 0.774 1.59 0.115 0.183 0.531 0.2746 1.12 0.783 1.61 PRS_PLINK_0.001 414.2 ASCVD Both 5 209 8 circulatory system red 209, 5 53, 1 52, 1 52, 2 52, 1 -0.0149 0.362 0.967 0.01447 0.985 0.485 2 -0.428 1.01 0.673 0.1722 0.652 0.0894 4.75 0.501 0.849 0.555 0.2556 1.65 0.313 8.71 -0.0972 0.923 0.916 0.03801 0.907 0.149 5.54 PRS_PLINK_0.001 415 Pulmonary heart disease Both 617 11178 8 circulatory system red 11178, 617 2795, 179 2794, 141 2794, 137 2795, 160 -0.067 0.0415 0.107 0.972 0.935 0.862 1.01 -0.215 0.115 0.0625 1.204 0.807 0.643 1.01 -0.247 0.116 0.0339 1.469 0.781 0.622 0.981 -0.0993 0.112 0.377 0.4238 0.906 0.727 1.13 PRS_PLINK_0.001 415.11 Pulmonary embolism and infarction, acute Both 13 181 8 circulatory system red 181, 13 46, 4 45, 3 45, 3 45, 3 -0.0594 0.286 0.836 0.07789 0.942 0.538 1.65 -0.624 0.815 0.444 0.3531 0.536 0.109 2.64 0.186 0.777 0.811 0.09081 1.2 0.262 5.52 -0.371 0.728 0.61 0.2144 0.69 0.166 2.88 PRS_PLINK_0.001 415.2 Chronic pulmonary heart disease Both 67 1447 8 circulatory system red 1447, 67 362, 26 362, 9 361, 14 362, 18 -0.108 0.122 0.379 0.4212 0.898 0.707 1.14 -1.01 0.373 0.0069 2.161 0.365 0.176 0.758 -0.629 0.328 0.0552 1.258 0.533 0.28 1.01 -0.324 0.306 0.289 0.5393 0.723 0.397 1.32 PRS_PLINK_0.001 415.21 Primary pulmonary hypertension Both 59 1065 8 circulatory system red 1065, 59 267, 24 266, 7 266, 12 266, 16 -0.148 0.131 0.259 0.5869 0.863 0.668 1.11 -1.12 0.411 0.00622 2.206 0.325 0.145 0.727 -0.769 0.355 0.0303 1.519 0.463 0.231 0.929 -0.392 0.324 0.227 0.6441 0.676 0.358 1.28 PRS_PLINK_0.001 416 Cardiomegaly Both 365 6542 8 circulatory system red 6542, 365 1636, 95 1635, 98 1635, 80 1636, 92 -0.0567 0.0533 0.287 0.5415 0.945 0.851 1.05 0.0228 0.147 0.877 0.05707 1.02 0.767 1.37 -0.166 0.155 0.283 0.5475 0.847 0.626 1.15 -0.0263 0.15 0.861 0.06515 0.974 0.726 1.31 PRS_PLINK_0.001 418 Nonspecific chest pain Both 5138 70197 8 circulatory system red 70197, 5138 17550, 1274 17549, 1264 17549, 1274 17549, 1326 0.00222 0.0145 0.878 0.05634 1 0.974 1.03 -0.0107 0.0411 0.795 0.09953 0.989 0.913 1.07 -0.00112 0.0411 0.978 0.009541 0.999 0.921 1.08 0.0359 0.0409 0.379 0.421 1.04 0.957 1.12 PRS_PLINK_0.001 418.1 Precordial pain Both 615 9180 8 circulatory system red 9180, 615 2295, 155 2295, 155 2295, 153 2295, 152 -0.000824 0.0416 0.984 0.006916 0.999 0.921 1.08 -0.0057 0.117 0.961 0.0172 0.994 0.79 1.25 -0.0148 0.118 0.9 0.04579 0.985 0.782 1.24 -0.0421 0.118 0.721 0.142 0.959 0.761 1.21 PRS_PLINK_0.001 420 Carditis Both 359 5274 8 circulatory system red 5274, 359 1319, 88 1318, 99 1318, 78 1319, 94 -0.00251 0.0542 0.963 0.01636 0.997 0.897 1.11 0.103 0.151 0.494 0.3059 1.11 0.825 1.49 -0.121 0.159 0.449 0.3474 0.886 0.649 1.21 0.078 0.153 0.611 0.2142 1.08 0.801 1.46 PRS_PLINK_0.001 420.1 Myocarditis Both 26 305 8 circulatory system red 305, 26 77, 6 76, 5 76, 7 76, 8 0.16 0.205 0.435 0.3618 1.17 0.785 1.75 -0.172 0.58 0.767 0.1151 0.842 0.27 2.63 0.258 0.586 0.659 0.1812 1.29 0.411 4.08 0.243 0.531 0.647 0.1889 1.28 0.45 3.61 PRS_PLINK_0.001 420.2 Pericarditis Both 217 3382 8 circulatory system red 3382, 217 846, 51 845, 64 845, 45 846, 57 0.0235 0.0695 0.735 0.1336 1.02 0.893 1.17 0.214 0.192 0.265 0.5773 1.24 0.851 1.8 -0.133 0.208 0.52 0.2839 0.875 0.583 1.31 0.0898 0.198 0.649 0.1876 1.09 0.743 1.61 PRS_PLINK_0.001 420.21 Acute pericarditis Both 41 563 8 circulatory system red 563, 41 141, 3 141, 8 140, 16 141, 14 0.392 0.154 0.0107 1.969 1.48 1.09 2 0.92 0.621 0.139 0.8574 2.51 0.742 8.48 1.49 0.568 0.00881 2.055 4.43 1.45 13.5 1.33 0.574 0.0208 1.682 3.77 1.22 11.6 PRS_PLINK_0.001 420.22 Chronic pericarditis Both 12 270 8 circulatory system red 270, 12 68, 4 67, 2 67, 5 68, 1 -0.107 0.308 0.727 0.1385 0.898 0.491 1.64 -0.36 0.758 0.635 0.1975 0.698 0.158 3.08 0.33 0.642 0.607 0.2171 1.39 0.395 4.9 -0.182 0.891 0.838 0.07683 0.833 0.145 4.77 PRS_PLINK_0.001 420.3 Endocarditis Both 130 1781 8 circulatory system red 1781, 130 446, 35 445, 33 445, 26 445, 36 -0.055 0.0902 0.542 0.2661 0.946 0.793 1.13 -0.119 0.249 0.634 0.1981 0.888 0.545 1.45 -0.307 0.263 0.243 0.6138 0.736 0.439 1.23 0.0484 0.245 0.843 0.07395 1.05 0.649 1.7 PRS_PLINK_0.001 425 Cardiomyopathy Both 229 3173 8 circulatory system red 3173, 229 794, 61 793, 51 793, 56 793, 61 -0.0295 0.0681 0.664 0.1776 0.971 0.85 1.11 -0.181 0.194 0.352 0.454 0.834 0.57 1.22 -0.12 0.191 0.53 0.2759 0.887 0.61 1.29 -0.00131 0.187 0.994 0.002432 0.999 0.692 1.44 PRS_PLINK_0.001 425.1 Primary/intrinsic cardiomyopathies Both 225 3077 8 circulatory system red 3077, 225 770, 59 769, 51 769, 56 769, 59 -0.0274 0.0687 0.69 0.1613 0.973 0.85 1.11 -0.152 0.196 0.437 0.3596 0.859 0.585 1.26 -0.0845 0.192 0.661 0.1801 0.919 0.63 1.34 -0.00441 0.19 0.982 0.00811 0.996 0.686 1.45 PRS_PLINK_0.001 425.11 Hypertrophic obstructive cardiomyopathy Both 29 328 8 circulatory system red 328, 29 82, 7 82, 9 82, 6 82, 7 -0.022 0.185 0.905 0.04318 0.978 0.681 1.41 0.214 0.515 0.678 0.1687 1.24 0.452 3.39 -0.496 0.577 0.39 0.4094 0.609 0.197 1.89 -0.335 0.542 0.536 0.2707 0.715 0.247 2.07 PRS_PLINK_0.001 425.12 Other hypertrophic cardiomyopathy Both 36 405 8 circulatory system red 405, 36 102, 15 101, 9 101, 6 101, 6 -0.388 0.161 0.0156 1.807 0.678 0.495 0.929 -0.51 0.429 0.235 0.6293 0.601 0.259 1.39 -1.1 0.493 0.0253 1.597 0.332 0.127 0.872 -0.928 0.483 0.0545 1.264 0.395 0.153 1.02 PRS_PLINK_0.001 425.8 Other cardiomyopathy Both 4 144 8 circulatory system red 144, 4 36, 1 36, 1 36, 0 36, 2 0.423 0.484 0.382 0.4179 1.53 0.591 3.94 0.549 1.21 0.651 0.1864 1.73 0.161 18.7 -0.714 1.14 0.532 0.2744 0.49 0.0524 4.58 0.603 1.21 0.618 0.2092 1.83 0.171 19.5 PRS_PLINK_0.001 426 Cardiac conduction disorders Both 1208 17059 8 circulatory system red 17059, 1208 4264, 319 4265, 284 4264, 292 4265, 313 0.00221 0.0297 0.941 0.02651 1 0.945 1.06 -0.108 0.0844 0.2 0.6992 0.898 0.761 1.06 -0.0945 0.0839 0.26 0.5853 0.91 0.772 1.07 -0.018 0.0828 0.828 0.0819 0.982 0.835 1.16 PRS_PLINK_0.001 426.2 Atrioventricular [AV] block Both 375 5200 8 circulatory system red 5200, 375 1300, 79 1300, 90 1300, 103 1300, 103 0.106 0.0538 0.0486 1.314 1.11 1 1.24 0.129 0.158 0.413 0.3842 1.14 0.835 1.55 0.255 0.154 0.0984 1.007 1.29 0.954 1.75 0.256 0.154 0.0969 1.014 1.29 0.955 1.75 PRS_PLINK_0.001 426.21 First degree AV block Both 174 2449 8 circulatory system red 2449, 174 613, 40 612, 41 612, 42 612, 51 0.075 0.0775 0.333 0.4773 1.08 0.926 1.25 0.0975 0.228 0.669 0.1748 1.1 0.706 1.72 0.126 0.227 0.579 0.2375 1.13 0.727 1.77 0.267 0.217 0.219 0.6586 1.31 0.853 2 PRS_PLINK_0.001 426.23 Second degree AV block Both 94 1103 8 circulatory system red 1103, 94 276, 18 276, 16 275, 30 276, 30 0.203 0.108 0.06 1.222 1.22 0.991 1.51 -0.0828 0.339 0.807 0.09295 0.921 0.473 1.79 0.514 0.304 0.0911 1.04 1.67 0.921 3.04 0.439 0.304 0.148 0.8284 1.55 0.855 2.81 PRS_PLINK_0.001 426.24 Atrioventricular block, complete Both 106 1415 8 circulatory system red 1415, 106 354, 23 354, 29 353, 27 354, 27 0.0854 0.103 0.406 0.3912 1.09 0.89 1.33 0.227 0.284 0.423 0.3741 1.26 0.72 2.19 0.122 0.286 0.671 0.1733 1.13 0.644 1.98 0.156 0.287 0.587 0.2311 1.17 0.666 2.05 PRS_PLINK_0.001 426.25 Other heart block Both 21 295 8 circulatory system red 295, 21 74, 2 74, 5 73, 8 74, 6 0.389 0.242 0.108 0.9669 1.47 0.918 2.37 0.653 0.703 0.353 0.4519 1.92 0.484 7.63 1.2 0.693 0.0837 1.077 3.31 0.853 12.9 0.942 0.7 0.179 0.7479 2.56 0.65 10.1 PRS_PLINK_0.001 426.3 Bundle branch block Both 573 8101 8 circulatory system red 8101, 573 2025, 164 2025, 121 2025, 132 2025, 156 -0.0118 0.0428 0.783 0.106 0.988 0.909 1.07 -0.289 0.123 0.0191 1.719 0.749 0.588 0.954 -0.227 0.121 0.0607 1.217 0.797 0.629 1.01 -0.0379 0.116 0.744 0.1282 0.963 0.767 1.21 PRS_PLINK_0.001 426.31 Right bundle branch block Both 266 3641 8 circulatory system red 3641, 266 910, 83 910, 57 910, 65 910, 61 -0.0776 0.0611 0.204 0.6904 0.925 0.821 1.04 -0.374 0.177 0.0343 1.465 0.688 0.486 0.973 -0.254 0.171 0.137 0.8631 0.776 0.555 1.08 -0.29 0.174 0.0961 1.017 0.749 0.532 1.05 PRS_PLINK_0.001 426.32 Left bundle branch block Both 290 4243 8 circulatory system red 4243, 290 1061, 74 1061, 61 1060, 62 1061, 93 0.0862 0.0609 0.157 0.8051 1.09 0.967 1.23 -0.181 0.176 0.304 0.5168 0.834 0.591 1.18 -0.193 0.176 0.273 0.5633 0.825 0.584 1.16 0.24 0.161 0.136 0.8659 1.27 0.927 1.74 PRS_PLINK_0.001 426.4 Anomalous atrioventricular excitation Both 58 673 8 circulatory system red 673, 58 169, 15 168, 14 168, 18 168, 11 -0.0709 0.134 0.598 0.2232 0.932 0.716 1.21 -0.0137 0.372 0.971 0.01296 0.986 0.476 2.04 0.142 0.357 0.69 0.1611 1.15 0.572 2.32 -0.219 0.393 0.578 0.2381 0.804 0.372 1.74 PRS_PLINK_0.001 426.8 Other cardiac conduction disorders Both 8 133 8 circulatory system red 133, 8 34, 2 33, 1 33, 4 33, 1 -0.136 0.337 0.686 0.1636 0.873 0.451 1.69 -0.933 1.03 0.365 0.4378 0.393 0.0522 2.96 0.354 0.851 0.677 0.1693 1.43 0.269 7.55 -0.646 0.969 0.505 0.2971 0.524 0.0785 3.5 PRS_PLINK_0.001 426.9 Cardiac pacemaker/device in situ Both 373 6088 8 circulatory system red 6088, 373 1522, 97 1522, 92 1522, 91 1522, 93 -0.007 0.0534 0.896 0.04783 0.993 0.894 1.1 -0.0591 0.149 0.691 0.1602 0.943 0.704 1.26 -0.0699 0.15 0.64 0.1935 0.932 0.695 1.25 -0.0413 0.15 0.783 0.1063 0.96 0.715 1.29 PRS_PLINK_0.001 426.91 Cardiac pacemaker in situ Both 344 5577 8 circulatory system red 5577, 344 1395, 91 1394, 87 1394, 78 1394, 88 -0.0154 0.0558 0.783 0.1062 0.985 0.883 1.1 -0.0507 0.154 0.741 0.1301 0.951 0.703 1.28 -0.166 0.158 0.294 0.5316 0.847 0.621 1.15 -0.0367 0.154 0.812 0.09064 0.964 0.713 1.3 PRS_PLINK_0.001 427 Cardiac dysrhythmias Both 4365 52962 8 circulatory system red 52962, 4365 13240, 1084 13240, 1089 13240, 1014 13241, 1178 0.0246 0.0158 0.12 0.9215 1.02 0.994 1.06 0.00538 0.0447 0.904 0.04372 1.01 0.921 1.1 -0.063 0.0455 0.166 0.7789 0.939 0.859 1.03 0.0874 0.0441 0.0476 1.323 1.09 1 1.19 PRS_PLINK_0.001 427.1 Paroxysmal tachycardia, unspecified Both 607 8203 8 circulatory system red 8203, 607 2051, 157 2051, 157 2050, 154 2051, 139 -0.0415 0.0422 0.325 0.488 0.959 0.883 1.04 -0.00142 0.117 0.99 0.004251 0.999 0.794 1.26 -0.0167 0.117 0.887 0.05196 0.983 0.781 1.24 -0.124 0.121 0.305 0.5152 0.884 0.698 1.12 PRS_PLINK_0.001 427.11 Paroxysmal supraventricular tachycardia Both 472 6026 8 circulatory system red 6026, 472 1507, 128 1506, 119 1506, 125 1507, 100 -0.0755 0.0474 0.111 0.9539 0.927 0.845 1.02 -0.069 0.132 0.601 0.221 0.933 0.721 1.21 -0.0124 0.131 0.924 0.03422 0.988 0.764 1.28 -0.243 0.138 0.0782 1.107 0.784 0.598 1.03 PRS_PLINK_0.001 427.12 Paroxysmal ventricular tachycardia Both 147 2371 8 circulatory system red 2371, 147 593, 40 593, 39 592, 31 593, 37 0.0165 0.0856 0.847 0.0721 1.02 0.86 1.2 -0.0509 0.23 0.825 0.08347 0.95 0.605 1.49 -0.265 0.242 0.272 0.565 0.767 0.478 1.23 -0.0823 0.233 0.724 0.1402 0.921 0.583 1.45 PRS_PLINK_0.001 427.2 Atrial fibrillation and flutter Both 2560 33529 8 circulatory system red 33529, 2560 8383, 608 8382, 658 8382, 608 8382, 686 0.0385 0.0206 0.0617 1.209 1.04 0.998 1.08 0.083 0.0583 0.155 0.8097 1.09 0.969 1.22 0.00332 0.0595 0.956 0.01973 1 0.893 1.13 0.13 0.0581 0.0259 1.587 1.14 1.02 1.28 PRS_PLINK_0.001 427.3 Other specified cardiac dysrhythmias Both 614 8184 8 circulatory system red 8184, 614 2045, 153 2046, 141 2046, 165 2046, 155 0.0189 0.0416 0.649 0.1877 1.02 0.939 1.11 -0.0735 0.12 0.542 0.2662 0.929 0.734 1.18 0.0933 0.116 0.422 0.3742 1.1 0.874 1.38 0.0341 0.118 0.773 0.1117 1.03 0.82 1.31 PRS_PLINK_0.001 427.4 Cardiac arrest and ventricular fibrillation Both 132 3049 8 circulatory system red 3049, 132 763, 29 762, 30 762, 31 762, 42 0.123 0.0885 0.163 0.7866 1.13 0.951 1.35 0.0468 0.258 0.856 0.06748 1.05 0.632 1.74 0.103 0.258 0.69 0.1609 1.11 0.668 1.84 0.353 0.242 0.144 0.8404 1.42 0.886 2.29 PRS_PLINK_0.001 427.41 Ventricular fibrillation and flutter Both 69 916 8 circulatory system red 916, 69 229, 17 229, 12 229, 18 229, 22 0.111 0.124 0.371 0.4301 1.12 0.876 1.43 -0.287 0.373 0.442 0.3549 0.751 0.361 1.56 0.129 0.344 0.708 0.1498 1.14 0.58 2.23 0.22 0.33 0.505 0.2967 1.25 0.652 2.38 PRS_PLINK_0.001 427.42 Cardiac arrest Both 90 2510 8 circulatory system red 2510, 90 628, 16 627, 25 627, 20 628, 29 0.106 0.106 0.319 0.4959 1.11 0.903 1.37 0.429 0.311 0.168 0.7742 1.54 0.834 2.82 0.195 0.326 0.55 0.2598 1.22 0.641 2.3 0.537 0.306 0.0791 1.102 1.71 0.939 3.12 PRS_PLINK_0.001 427.5 Arrhythmia (cardiac) NOS Both 178 2360 8 circulatory system red 2360, 178 590, 50 590, 34 590, 36 590, 58 0.027 0.0776 0.728 0.1379 1.03 0.882 1.2 -0.398 0.228 0.0801 1.096 0.671 0.43 1.05 -0.302 0.224 0.177 0.7508 0.739 0.477 1.15 0.149 0.2 0.455 0.3416 1.16 0.784 1.72 PRS_PLINK_0.001 427.6 Premature beats Both 116 1405 8 circulatory system red 1405, 116 352, 26 351, 32 351, 29 351, 29 -0.00233 0.0954 0.98 0.008555 0.998 0.828 1.2 0.205 0.268 0.445 0.3517 1.23 0.726 2.08 0.139 0.276 0.615 0.211 1.15 0.669 1.97 0.101 0.276 0.713 0.1467 1.11 0.644 1.9 PRS_PLINK_0.001 427.61 Supraventricular premature beats Both 23 314 8 circulatory system red 314, 23 79, 5 78, 9 78, 1 79, 8 0.137 0.203 0.502 0.2996 1.15 0.77 1.71 0.64 0.544 0.239 0.622 1.9 0.654 5.5 -1.32 0.89 0.139 0.8578 0.268 0.0467 1.53 0.58 0.582 0.32 0.4954 1.79 0.57 5.59 PRS_PLINK_0.001 427.7 Tachycardia NOS Both 274 5557 8 circulatory system red 5557, 274 1390, 73 1389, 65 1389, 62 1389, 74 0.0218 0.0624 0.726 0.1388 1.02 0.904 1.15 -0.126 0.173 0.468 0.3297 0.882 0.628 1.24 -0.151 0.175 0.389 0.4099 0.86 0.61 1.21 0.0414 0.169 0.806 0.09347 1.04 0.749 1.45 PRS_PLINK_0.001 427.8 Sinoatrial node dysfunction (Bradycardia) Both 79 993 8 circulatory system red 993, 79 249, 14 248, 14 248, 27 248, 24 0.299 0.122 0.0141 1.852 1.35 1.06 1.71 0.0267 0.371 0.943 0.02567 1.03 0.496 2.13 0.655 0.33 0.0473 1.325 1.93 1.01 3.68 0.459 0.339 0.175 0.7557 1.58 0.815 3.07 PRS_PLINK_0.001 427.9 Palpitations Both 791 9698 8 circulatory system red 9698, 791 2425, 228 2424, 180 2424, 165 2425, 218 -0.0317 0.0367 0.387 0.4121 0.969 0.902 1.04 -0.233 0.103 0.0241 1.618 0.792 0.647 0.97 -0.312 0.106 0.00326 2.487 0.732 0.594 0.901 -0.0459 0.0991 0.643 0.1917 0.955 0.786 1.16 PRS_PLINK_0.001 428 Congestive heart failure; nonhypertensive Both 563 13485 8 circulatory system red 13485, 563 3372, 138 3371, 133 3371, 143 3371, 149 0.0308 0.0431 0.474 0.3239 1.03 0.948 1.12 -0.035 0.123 0.777 0.1098 0.966 0.758 1.23 0.0459 0.122 0.706 0.1514 1.05 0.825 1.33 0.0984 0.121 0.415 0.3815 1.1 0.871 1.4 PRS_PLINK_0.001 428.1 Congestive heart failure (CHF) NOS Both 162 5071 8 circulatory system red 5071, 162 1268, 44 1268, 37 1267, 33 1268, 48 -0.00383 0.0785 0.961 0.01722 0.996 0.854 1.16 -0.152 0.222 0.493 0.307 0.859 0.556 1.33 -0.276 0.229 0.229 0.6402 0.759 0.484 1.19 0.109 0.21 0.605 0.2185 1.11 0.738 1.68 PRS_PLINK_0.001 428.2 Heart failure NOS Both 461 10646 8 circulatory system red 10646, 461 2662, 109 2661, 113 2661, 122 2662, 117 0.0302 0.0478 0.527 0.2783 1.03 0.939 1.13 0.0376 0.136 0.782 0.1065 1.04 0.795 1.36 0.121 0.134 0.367 0.4359 1.13 0.868 1.47 0.0919 0.136 0.498 0.3025 1.1 0.84 1.43 PRS_PLINK_0.001 429 Ill-defined descriptions and complications of heart disease Both 144 1835 8 circulatory system red 1835, 144 459, 43 459, 35 458, 34 459, 32 -0.06 0.0887 0.499 0.3022 0.942 0.791 1.12 -0.197 0.233 0.399 0.3988 0.822 0.52 1.3 -0.188 0.236 0.427 0.3699 0.829 0.522 1.32 -0.278 0.24 0.248 0.6053 0.758 0.473 1.21 PRS_PLINK_0.001 429.1 Heart transplant/surgery Both 11 160 8 circulatory system red 160, 11 40, 7 40, 1 40, 2 40, 1 -0.575 0.309 0.0629 1.201 0.563 0.307 1.03 -1.49 0.821 0.0696 1.157 0.225 0.0451 1.13 -0.963 0.696 0.167 0.7784 0.382 0.0976 1.49 -1.52 0.815 0.0619 1.208 0.218 0.0442 1.08 PRS_PLINK_0.001 429.2 Abnormal function study of cardiovascular system Both 104 1333 8 circulatory system red 1333, 104 334, 30 333, 23 333, 22 333, 29 0.00443 0.105 0.966 0.01495 1 0.818 1.23 -0.264 0.28 0.347 0.4592 0.768 0.443 1.33 -0.273 0.287 0.341 0.467 0.761 0.434 1.34 -0.00677 0.27 0.98 0.008757 0.993 0.585 1.69 PRS_PLINK_0.001 429.3 Symptoms involving cardiovascular system Both 40 511 8 circulatory system red 511, 40 128, 13 128, 12 127, 11 128, 4 -0.245 0.167 0.143 0.8446 0.783 0.564 1.09 -0.0476 0.403 0.906 0.04279 0.954 0.432 2.1 -0.122 0.411 0.767 0.1151 0.885 0.396 1.98 -1.13 0.542 0.0371 1.431 0.323 0.112 0.935 PRS_PLINK_0.001 430 Intracranial hemorrhage Both 268 4716 8 circulatory system red 4716, 268 1179, 75 1179, 67 1179, 62 1179, 64 -0.0771 0.0637 0.226 0.6455 0.926 0.817 1.05 -0.114 0.171 0.507 0.2946 0.893 0.638 1.25 -0.148 0.176 0.403 0.3949 0.863 0.611 1.22 -0.167 0.175 0.339 0.4694 0.846 0.6 1.19 PRS_PLINK_0.001 430.1 Subarachnoid hemorrhage Both 152 2136 8 circulatory system red 2136, 152 534, 46 534, 31 534, 36 534, 39 -0.0649 0.084 0.44 0.3565 0.937 0.795 1.1 -0.406 0.237 0.0874 1.059 0.667 0.419 1.06 -0.26 0.229 0.256 0.5919 0.771 0.492 1.21 -0.196 0.225 0.383 0.4168 0.822 0.528 1.28 PRS_PLINK_0.001 430.2 Intracerebral hemorrhage Both 77 1877 8 circulatory system red 1877, 77 470, 20 469, 27 469, 12 469, 18 -0.0999 0.114 0.38 0.4203 0.905 0.724 1.13 0.297 0.291 0.309 0.5099 1.35 0.76 2.38 -0.437 0.354 0.217 0.663 0.646 0.323 1.29 -0.0867 0.322 0.788 0.1037 0.917 0.488 1.72 PRS_PLINK_0.001 430.3 Subdural hemorrhage Both 37 626 8 circulatory system red 626, 37 157, 9 156, 11 156, 9 157, 8 -0.0729 0.163 0.654 0.1844 0.93 0.676 1.28 0.205 0.438 0.639 0.1947 1.23 0.521 2.9 0.0443 0.45 0.922 0.03543 1.05 0.432 2.53 -0.0971 0.464 0.834 0.07868 0.907 0.365 2.25 PRS_PLINK_0.001 433 Cerebrovascular disease Both 1172 21552 8 circulatory system red 21552, 1172 5388, 298 5388, 290 5388, 280 5388, 304 -0.00123 0.0301 0.967 0.01445 0.999 0.942 1.06 -0.0215 0.0846 0.799 0.09734 0.979 0.829 1.16 -0.0461 0.0855 0.59 0.2293 0.955 0.808 1.13 0.0485 0.0841 0.564 0.2484 1.05 0.89 1.24 PRS_PLINK_0.001 433.1 Occlusion and stenosis of precerebral arteries Both 130 2816 8 circulatory system red 2816, 130 704, 29 704, 34 704, 30 704, 37 0.0162 0.0887 0.855 0.06824 1.02 0.854 1.21 0.167 0.251 0.507 0.2954 1.18 0.722 1.93 0.0534 0.259 0.836 0.07757 1.05 0.635 1.75 0.295 0.25 0.238 0.6236 1.34 0.823 2.19 PRS_PLINK_0.001 433.12 Cerebral atherosclerosis Both 19 547 8 circulatory system red 547, 19 137, 3 137, 4 136, 6 137, 6 0.14 0.219 0.523 0.2815 1.15 0.748 1.77 0.261 0.637 0.682 0.1665 1.3 0.373 4.52 0.503 0.613 0.412 0.3855 1.65 0.498 5.5 0.572 0.616 0.354 0.4515 1.77 0.529 5.93 PRS_PLINK_0.001 433.2 Occlusion of cerebral arteries Both 508 10312 8 circulatory system red 10312, 508 2578, 131 2578, 122 2578, 121 2578, 134 -0.00125 0.0451 0.978 0.009694 0.999 0.914 1.09 -0.0662 0.128 0.605 0.218 0.936 0.728 1.2 -0.0597 0.129 0.643 0.1918 0.942 0.732 1.21 0.0442 0.126 0.726 0.1391 1.05 0.816 1.34 PRS_PLINK_0.001 433.21 Cerebral artery occlusion, with cerebral infarction Both 182 4145 8 circulatory system red 4145, 182 1037, 51 1036, 43 1036, 43 1036, 45 -0.0453 0.0752 0.547 0.2622 0.956 0.825 1.11 -0.13 0.208 0.531 0.2746 0.878 0.583 1.32 -0.149 0.209 0.474 0.3245 0.861 0.572 1.3 -0.0887 0.207 0.668 0.1751 0.915 0.61 1.37 PRS_PLINK_0.001 433.3 Cerebral ischemia Both 406 7118 8 circulatory system red 7118, 406 1780, 104 1779, 95 1779, 96 1780, 111 0.0179 0.0511 0.726 0.139 1.02 0.921 1.13 -0.0833 0.145 0.565 0.2476 0.92 0.693 1.22 -0.0773 0.145 0.593 0.2269 0.926 0.697 1.23 0.1 0.141 0.476 0.3222 1.11 0.839 1.46 PRS_PLINK_0.001 433.31 Transient cerebral ischemia Both 335 5282 8 circulatory system red 5282, 335 1321, 88 1320, 79 1320, 76 1321, 92 0.0191 0.057 0.738 0.1322 1.02 0.912 1.14 -0.109 0.159 0.492 0.308 0.897 0.657 1.22 -0.15 0.16 0.349 0.4568 0.861 0.629 1.18 0.0753 0.154 0.625 0.204 1.08 0.797 1.46 PRS_PLINK_0.001 433.5 Cerebral aneurysm Both 53 1039 8 circulatory system red 1039, 53 260, 17 260, 12 259, 9 260, 15 -0.0188 0.144 0.896 0.04767 0.981 0.74 1.3 -0.331 0.366 0.366 0.4362 0.718 0.351 1.47 -0.588 0.398 0.14 0.8551 0.555 0.254 1.21 -0.0946 0.353 0.789 0.103 0.91 0.455 1.82 PRS_PLINK_0.001 433.8 Late effects of cerebrovascular disease Both 103 3276 8 circulatory system red 3276, 103 819, 30 819, 22 819, 26 819, 25 -0.0714 0.098 0.466 0.3313 0.931 0.768 1.13 -0.292 0.277 0.292 0.5347 0.747 0.434 1.28 -0.136 0.267 0.611 0.214 0.873 0.517 1.47 -0.159 0.271 0.557 0.2541 0.853 0.501 1.45 PRS_PLINK_0.001 440 Atherosclerosis Both 161 3232 8 circulatory system red 3232, 161 808, 41 808, 37 808, 33 808, 50 0.107 0.0807 0.184 0.7344 1.11 0.95 1.3 -0.105 0.228 0.644 0.1909 0.9 0.576 1.41 -0.187 0.234 0.424 0.3722 0.829 0.524 1.31 0.26 0.214 0.226 0.646 1.3 0.852 1.97 PRS_PLINK_0.001 440.1 Atherosclerosis of renal artery Both 9 280 8 circulatory system red 280, 9 70, 4 70, 1 70, 2 70, 2 -0.0265 0.304 0.931 0.0312 0.974 0.536 1.77 -1.32 0.85 0.12 0.9203 0.267 0.0505 1.41 -0.786 0.733 0.283 0.5477 0.455 0.108 1.92 -0.623 0.715 0.384 0.4157 0.536 0.132 2.18 PRS_PLINK_0.001 440.2 Atherosclerosis of the extremities Both 93 1851 8 circulatory system red 1851, 93 463, 22 463, 23 462, 20 463, 28 0.101 0.105 0.339 0.4693 1.11 0.9 1.36 0.0136 0.295 0.963 0.01627 1.01 0.569 1.81 -0.0873 0.304 0.774 0.1112 0.916 0.505 1.66 0.267 0.285 0.349 0.4566 1.31 0.747 2.28 PRS_PLINK_0.001 440.9 Atherosclerosis of aorta Both 36 667 8 circulatory system red 667, 36 167, 10 167, 10 166, 4 167, 12 0.0762 0.168 0.65 0.1868 1.08 0.776 1.5 -0.0112 0.449 0.98 0.008704 0.989 0.411 2.38 -0.959 0.573 0.094 1.027 0.383 0.125 1.18 0.289 0.441 0.512 0.2908 1.34 0.562 3.17 PRS_PLINK_0.001 441 Vascular insufficiency of intestine Both 83 1480 8 circulatory system red 1480, 83 370, 26 370, 23 370, 14 370, 20 -0.154 0.109 0.157 0.8029 0.857 0.692 1.06 -0.128 0.286 0.654 0.1845 0.879 0.502 1.54 -0.579 0.326 0.0759 1.12 0.561 0.296 1.06 -0.24 0.296 0.418 0.3783 0.787 0.44 1.41 PRS_PLINK_0.001 441.1 Acute vascular insufficiency of intestine Both 34 716 8 circulatory system red 716, 34 179, 10 179, 9 179, 3 179, 12 0.0577 0.175 0.742 0.1296 1.06 0.752 1.49 -0.0816 0.441 0.853 0.06899 0.922 0.389 2.19 -1.22 0.591 0.0385 1.414 0.294 0.0923 0.938 0.223 0.417 0.593 0.227 1.25 0.552 2.83 PRS_PLINK_0.001 442 Other aneurysm Both 324 4600 8 circulatory system red 4600, 324 1150, 98 1150, 72 1150, 75 1150, 79 -0.087 0.0566 0.125 0.9045 0.917 0.82 1.02 -0.301 0.159 0.0594 1.226 0.74 0.542 1.01 -0.262 0.158 0.0979 1.009 0.77 0.565 1.05 -0.195 0.157 0.214 0.6698 0.823 0.606 1.12 PRS_PLINK_0.001 442.1 Aortic aneurysm Both 234 3517 8 circulatory system red 3517, 234 880, 72 879, 56 879, 54 879, 52 -0.113 0.0661 0.0872 1.059 0.893 0.785 1.02 -0.239 0.183 0.191 0.7195 0.788 0.551 1.13 -0.285 0.185 0.122 0.9121 0.752 0.524 1.08 -0.323 0.187 0.0842 1.075 0.724 0.502 1.04 PRS_PLINK_0.001 442.11 Abdominal aortic aneurysm Both 154 2145 8 circulatory system red 2145, 154 537, 48 536, 28 536, 41 536, 37 -0.0889 0.0818 0.277 0.5568 0.915 0.779 1.07 -0.509 0.241 0.0348 1.458 0.601 0.375 0.964 -0.157 0.219 0.474 0.3243 0.855 0.556 1.31 -0.23 0.224 0.303 0.5183 0.794 0.512 1.23 PRS_PLINK_0.001 442.2 Aneurysm of iliac artery Both 20 229 8 circulatory system red 229, 20 58, 6 57, 3 57, 3 57, 8 -0.0495 0.224 0.825 0.08363 0.952 0.614 1.48 -0.625 0.681 0.358 0.4457 0.535 0.141 2.03 -0.66 0.647 0.308 0.5121 0.517 0.146 1.84 0.147 0.541 0.786 0.1047 1.16 0.401 3.34 PRS_PLINK_0.001 442.3 Aneurysm of artery of lower extremity Both 39 401 8 circulatory system red 401, 39 101, 7 100, 7 100, 10 100, 15 0.118 0.164 0.472 0.3264 1.12 0.816 1.55 -0.0596 0.513 0.908 0.04215 0.942 0.345 2.58 0.408 0.483 0.398 0.4001 1.5 0.584 3.88 0.721 0.464 0.12 0.9212 2.06 0.829 5.1 PRS_PLINK_0.001 442.4 Arterial dissection Both 14 148 8 circulatory system red 148, 14 37, 5 37, 4 37, 4 37, 1 -0.345 0.228 0.129 0.8881 0.708 0.453 1.11 -0.00413 0.674 0.995 0.002125 0.996 0.266 3.73 -0.332 0.704 0.637 0.1958 0.717 0.18 2.85 -1.03 0.844 0.222 0.6539 0.357 0.0681 1.87 PRS_PLINK_0.001 442.8 Aneurysm of other specified artery Both 37 522 8 circulatory system red 522, 37 131, 13 130, 6 130, 5 131, 13 -0.0664 0.167 0.69 0.1611 0.936 0.675 1.3 -0.691 0.471 0.143 0.8455 0.501 0.199 1.26 -0.888 0.503 0.0771 1.113 0.411 0.154 1.1 0.17 0.406 0.676 0.1702 1.19 0.534 2.63 PRS_PLINK_0.001 443 Peripheral vascular disease Both 495 9540 8 circulatory system red 9540, 495 2385, 131 2385, 116 2385, 118 2385, 130 -0.0144 0.0459 0.753 0.1231 0.986 0.901 1.08 -0.12 0.13 0.355 0.45 0.887 0.687 1.14 -0.116 0.13 0.373 0.4287 0.891 0.691 1.15 0.000519 0.127 0.997 0.001419 1 0.78 1.28 PRS_PLINK_0.001 443.1 Raynaud's syndrome Both 228 2937 8 circulatory system red 2937, 228 735, 62 734, 55 734, 61 734, 50 -0.082 0.0681 0.229 0.6404 0.921 0.806 1.05 -0.102 0.191 0.592 0.2277 0.903 0.621 1.31 -0.0126 0.186 0.946 0.02406 0.988 0.686 1.42 -0.202 0.196 0.302 0.5206 0.817 0.557 1.2 PRS_PLINK_0.001 443.7 Peripheral angiopathy in diseases classified elsewhere Both 23 965 8 circulatory system red 965, 23 242, 8 241, 9 241, 3 241, 3 -0.317 0.18 0.0788 1.103 0.728 0.512 1.04 0.101 0.455 0.824 0.08396 1.11 0.454 2.7 -1.02 0.589 0.0826 1.083 0.36 0.113 1.14 -0.75 0.582 0.197 0.7047 0.472 0.151 1.48 PRS_PLINK_0.001 443.8 Other specified peripheral vascular diseases Both 481 8895 8 circulatory system red 8895, 481 2224, 127 2224, 110 2223, 116 2224, 128 -0.00315 0.0467 0.946 0.02398 0.997 0.91 1.09 -0.14 0.133 0.291 0.5361 0.869 0.67 1.13 -0.0972 0.131 0.459 0.338 0.907 0.701 1.17 0.0161 0.128 0.9 0.04571 1.02 0.79 1.31 PRS_PLINK_0.001 443.9 Peripheral vascular disease, unspecified Both 259 6058 8 circulatory system red 6058, 259 1515, 67 1514, 58 1514, 58 1515, 76 0.058 0.0636 0.362 0.4415 1.06 0.936 1.2 -0.153 0.181 0.396 0.4023 0.858 0.602 1.22 -0.152 0.181 0.401 0.3972 0.859 0.602 1.22 0.146 0.17 0.392 0.4066 1.16 0.829 1.62 PRS_PLINK_0.001 444 Arterial embolism and thrombosis Both 98 2236 8 circulatory system red 2236, 98 559, 23 559, 22 559, 24 559, 29 0.0864 0.102 0.397 0.4016 1.09 0.893 1.33 -0.041 0.294 0.889 0.05119 0.96 0.54 1.71 0.0654 0.288 0.82 0.08613 1.07 0.608 1.88 0.261 0.277 0.347 0.4598 1.3 0.754 2.24 PRS_PLINK_0.001 444.1 Arterial embolism and thrombosis of lower extremity artery Both 58 1326 8 circulatory system red 1326, 58 332, 12 331, 12 331, 16 332, 18 0.192 0.134 0.152 0.8172 1.21 0.932 1.57 -0.00792 0.388 0.984 0.007125 0.992 0.463 2.12 0.235 0.368 0.524 0.281 1.26 0.615 2.6 0.415 0.364 0.254 0.5951 1.51 0.742 3.09 PRS_PLINK_0.001 446 Polyarteritis nodosa and allied conditions Both 147 1991 8 circulatory system red 1991, 147 498, 28 498, 42 497, 38 498, 39 0.101 0.0852 0.235 0.6292 1.11 0.936 1.31 0.368 0.247 0.137 0.8627 1.44 0.889 2.34 0.29 0.253 0.251 0.5995 1.34 0.814 2.19 0.376 0.253 0.137 0.8629 1.46 0.887 2.39 PRS_PLINK_0.001 446.4 Wegener's granulomatosis Both 44 492 8 circulatory system red 492, 44 123, 8 123, 13 123, 13 123, 10 0.107 0.153 0.484 0.3152 1.11 0.825 1.5 0.466 0.447 0.297 0.5268 1.59 0.663 3.83 0.424 0.444 0.34 0.4684 1.53 0.639 3.65 0.22 0.469 0.638 0.195 1.25 0.497 3.12 PRS_PLINK_0.001 446.5 Giant cell arteritis Both 57 920 8 circulatory system red 920, 57 230, 14 230, 12 230, 13 230, 18 0.0772 0.132 0.559 0.2524 1.08 0.834 1.4 -0.192 0.382 0.615 0.2109 0.825 0.39 1.75 -0.0977 0.377 0.795 0.0995 0.907 0.434 1.9 0.265 0.354 0.454 0.3432 1.3 0.651 2.61 PRS_PLINK_0.001 446.9 Arteritis NOS Both 46 580 8 circulatory system red 580, 46 145, 8 145, 11 145, 14 145, 13 0.143 0.155 0.356 0.449 1.15 0.852 1.56 0.0535 0.462 0.908 0.042 1.05 0.426 2.61 0.377 0.436 0.387 0.4128 1.46 0.621 3.43 0.49 0.437 0.262 0.5817 1.63 0.694 3.84 PRS_PLINK_0.001 447 Other disorders of arteries and arterioles Both 173 3243 8 circulatory system red 3243, 173 811, 37 811, 36 810, 43 811, 57 0.163 0.0769 0.0336 1.473 1.18 1.01 1.37 -0.0344 0.234 0.883 0.05396 0.966 0.61 1.53 0.137 0.226 0.543 0.2651 1.15 0.737 1.79 0.453 0.214 0.0346 1.461 1.57 1.03 2.39 PRS_PLINK_0.001 447.1 Stricture of artery Both 90 2082 8 circulatory system red 2082, 90 521, 16 520, 22 520, 27 521, 25 0.213 0.106 0.0447 1.349 1.24 1.01 1.52 0.303 0.318 0.341 0.4669 1.35 0.725 2.53 0.468 0.31 0.131 0.8838 1.6 0.87 2.93 0.501 0.314 0.111 0.9549 1.65 0.891 3.06 PRS_PLINK_0.001 448 Disease of capillaries Both 25 349 8 circulatory system red 349, 25 88, 8 87, 4 87, 8 87, 5 0.153 0.208 0.463 0.3344 1.17 0.775 1.75 -0.726 0.581 0.211 0.6748 0.484 0.155 1.51 -0.183 0.51 0.72 0.143 0.833 0.307 2.26 -0.447 0.561 0.426 0.3707 0.64 0.213 1.92 PRS_PLINK_0.001 450 Noninfectious disorders of lymphatic channels Both 103 1795 8 circulatory system red 1795, 103 449, 24 449, 23 448, 28 449, 28 0.064 0.101 0.527 0.2784 1.07 0.874 1.3 -0.0539 0.291 0.853 0.06912 0.947 0.536 1.68 0.186 0.279 0.505 0.2966 1.2 0.697 2.08 0.149 0.28 0.593 0.2268 1.16 0.671 2.01 PRS_PLINK_0.001 451 Phlebitis and thrombophlebitis Both 677 10181 8 circulatory system red 10181, 677 2546, 166 2545, 163 2545, 172 2545, 176 0.0213 0.0406 0.6 0.2222 1.02 0.943 1.11 -0.0168 0.113 0.882 0.05442 0.983 0.787 1.23 0.0372 0.112 0.74 0.1306 1.04 0.833 1.29 0.0439 0.112 0.696 0.1576 1.04 0.839 1.3 PRS_PLINK_0.001 451.2 Phlebitis and thrombophlebitis of lower extremities Both 632 9446 8 circulatory system red 9446, 632 2362, 157 2361, 153 2361, 160 2362, 162 0.0118 0.042 0.779 0.1087 1.01 0.932 1.1 -0.0261 0.117 0.824 0.08429 0.974 0.775 1.23 0.0217 0.116 0.851 0.06992 1.02 0.814 1.28 0.0168 0.116 0.885 0.05314 1.02 0.81 1.28 PRS_PLINK_0.001 452 Other venous embolism and thrombosis Both 75 1465 8 circulatory system red 1465, 75 367, 18 366, 24 366, 13 366, 20 -0.0113 0.114 0.921 0.03566 0.989 0.79 1.24 0.259 0.31 0.405 0.3927 1.3 0.705 2.38 -0.368 0.355 0.299 0.5236 0.692 0.345 1.39 -0.064 0.328 0.846 0.07286 0.938 0.493 1.79 PRS_PLINK_0.001 454 Varicose veins Both 2436 29007 8 circulatory system red 29007, 2436 7252, 567 7252, 635 7251, 576 7252, 658 0.0308 0.0213 0.148 0.8304 1.03 0.989 1.08 0.11 0.0601 0.0674 1.171 1.12 0.992 1.26 0.0172 0.0616 0.78 0.1077 1.02 0.902 1.15 0.135 0.06 0.0246 1.609 1.14 1.02 1.29 PRS_PLINK_0.001 454.1 Varicose veins of lower extremity Both 2512 29718 8 circulatory system red 29718, 2512 7430, 587 7429, 648 7429, 593 7430, 684 0.0312 0.021 0.138 0.8613 1.03 0.99 1.07 0.0969 0.0593 0.102 0.9895 1.1 0.981 1.24 0.0128 0.0606 0.833 0.07937 1.01 0.899 1.14 0.14 0.0589 0.0174 1.759 1.15 1.02 1.29 PRS_PLINK_0.001 454.11 Varicose veins of lower extremity, symptomtic Both 118 1572 8 circulatory system red 1572, 118 393, 28 393, 26 393, 26 393, 38 0.167 0.0939 0.0761 1.119 1.18 0.983 1.42 -0.0775 0.277 0.779 0.1083 0.925 0.538 1.59 -0.0964 0.278 0.729 0.1375 0.908 0.527 1.57 0.304 0.255 0.234 0.6306 1.35 0.822 2.23 PRS_PLINK_0.001 455 Hemorrhoids Both 5193 60512 8 circulatory system red 60512, 5193 15127, 1255 15128, 1380 15128, 1267 15128, 1291 0.00584 0.0145 0.687 0.1628 1.01 0.978 1.03 0.0997 0.0407 0.0143 1.844 1.1 1.02 1.2 0.0193 0.0416 0.643 0.1921 1.02 0.94 1.11 0.0356 0.0415 0.39 0.4084 1.04 0.955 1.12 PRS_PLINK_0.001 456 Chronic venous insufficiency [CVI] Both 27 468 8 circulatory system red 468, 27 117, 10 117, 5 117, 6 117, 6 -0.265 0.192 0.168 0.7736 0.767 0.526 1.12 -0.543 0.511 0.288 0.5411 0.581 0.213 1.58 -0.563 0.508 0.267 0.573 0.569 0.211 1.54 -0.452 0.501 0.367 0.435 0.637 0.238 1.7 PRS_PLINK_0.001 457 Encounter for long-term (current) use of anticoagulants, antithrombotics, aspirin Both 34 231 8 circulatory system red 231, 34 58, 10 58, 6 57, 6 58, 12 0.0786 0.198 0.691 0.1602 1.08 0.734 1.59 -0.305 0.538 0.571 0.2435 0.737 0.257 2.12 -0.609 0.549 0.267 0.5736 0.544 0.185 1.59 0.178 0.46 0.699 0.1553 1.19 0.485 2.94 PRS_PLINK_0.001 458 Hypotension Both 859 14581 8 circulatory system red 14581, 859 3646, 209 3645, 256 3645, 197 3645, 197 -0.0567 0.035 0.105 0.9785 0.945 0.882 1.01 0.212 0.0961 0.0274 1.561 1.24 1.02 1.49 -0.0557 0.102 0.584 0.2333 0.946 0.775 1.15 -0.0489 0.102 0.633 0.1989 0.952 0.779 1.16 PRS_PLINK_0.001 458.1 Orthostatic hypotension Both 134 3265 8 circulatory system red 3265, 134 817, 23 816, 47 816, 31 816, 33 0.0373 0.0871 0.669 0.1749 1.04 0.875 1.23 0.702 0.253 0.00544 2.265 2.02 1.23 3.31 0.29 0.271 0.283 0.5479 1.34 0.787 2.27 0.376 0.268 0.161 0.7936 1.46 0.861 2.46 PRS_PLINK_0.001 458.2 Iatrogenic hypotension Both 35 592 8 circulatory system red 592, 35 148, 9 148, 11 148, 7 148, 8 -0.101 0.167 0.548 0.2611 0.904 0.651 1.26 0.21 0.438 0.631 0.2 1.23 0.523 2.91 -0.282 0.481 0.558 0.2533 0.754 0.294 1.94 -0.126 0.465 0.787 0.1041 0.882 0.355 2.19 PRS_PLINK_0.001 458.9 Hypotension NOS Both 550 8817 8 circulatory system red 8817, 550 2205, 133 2204, 162 2204, 123 2204, 132 -0.0438 0.0442 0.321 0.4929 0.957 0.878 1.04 0.21 0.121 0.0812 1.091 1.23 0.974 1.56 -0.081 0.128 0.529 0.2768 0.922 0.717 1.19 -0.024 0.127 0.85 0.07063 0.976 0.762 1.25 PRS_PLINK_0.001 459 Other disorders of circulatory system Both 2523 40694 8 circulatory system red 40694, 2523 10174, 648 10173, 624 10173, 602 10174, 649 -0.0115 0.0206 0.577 0.2392 0.989 0.95 1.03 -0.0323 0.0578 0.576 0.2397 0.968 0.864 1.08 -0.0695 0.0584 0.234 0.6308 0.933 0.832 1.05 0.00618 0.0576 0.915 0.03879 1.01 0.899 1.13 PRS_PLINK_0.001 459.1 Hemorrhage NOS Both 15 322 8 circulatory system red 322, 15 81, 3 80, 3 80, 4 81, 5 0.185 0.251 0.461 0.3359 1.2 0.736 1.97 0.3 0.726 0.68 0.1675 1.35 0.325 5.6 0.312 0.726 0.667 0.1758 1.37 0.329 5.67 -0.0266 0.678 0.969 0.01383 0.974 0.258 3.68 PRS_PLINK_0.001 459.9 Circulatory disease NEC Both 2512 40368 8 circulatory system red 40368, 2512 10092, 648 10092, 625 10092, 598 10092, 641 -0.0152 0.0206 0.461 0.3359 0.985 0.946 1.03 -0.0308 0.0578 0.594 0.2265 0.97 0.866 1.09 -0.0766 0.0585 0.191 0.72 0.926 0.826 1.04 -0.00545 0.0577 0.925 0.03393 0.995 0.888 1.11 PRS_PLINK_0.001 464 Acute sinusitis Both 40 472 9 respiratory coral4 472, 40 118, 9 118, 9 118, 7 118, 15 0.143 0.157 0.363 0.4402 1.15 0.848 1.57 -0.103 0.468 0.826 0.08311 0.902 0.36 2.26 -0.235 0.499 0.637 0.1957 0.79 0.297 2.1 0.545 0.428 0.203 0.6917 1.72 0.745 3.99 PRS_PLINK_0.001 465 Acute upper respiratory infections of multiple or unspecified sites Both 424 5899 9 respiratory coral4 5899, 424 1475, 108 1475, 97 1474, 110 1475, 109 0.00272 0.0509 0.957 0.01892 1 0.907 1.11 -0.104 0.144 0.47 0.3282 0.901 0.68 1.19 0.0468 0.14 0.739 0.1315 1.05 0.796 1.38 0.0187 0.141 0.894 0.04864 1.02 0.773 1.34 PRS_PLINK_0.001 465.2 Acute pharyngitis Both 166 2181 9 respiratory coral4 2181, 166 546, 37 545, 37 545, 48 545, 44 0.0568 0.0817 0.487 0.3124 1.06 0.902 1.24 -0.00695 0.236 0.976 0.01033 0.993 0.626 1.58 0.28 0.224 0.211 0.675 1.32 0.853 2.05 0.142 0.227 0.533 0.273 1.15 0.738 1.8 PRS_PLINK_0.001 465.4 Acute laryngitis and tracheitis Both 26 405 9 respiratory coral4 405, 26 102, 10 101, 2 101, 5 101, 9 0.114 0.2 0.57 0.2444 1.12 0.757 1.66 -1.37 0.66 0.038 1.42 0.254 0.0697 0.927 -0.563 0.519 0.278 0.5563 0.569 0.206 1.57 -0.0833 0.462 0.857 0.06707 0.92 0.372 2.28 PRS_PLINK_0.001 470 Septal Deviations/Turbinate Hypertrophy Both 1012 11988 9 respiratory coral4 11988, 1012 2997, 244 2997, 250 2997, 254 2997, 264 0.0143 0.033 0.664 0.1777 1.01 0.951 1.08 0.01 0.0936 0.915 0.03879 1.01 0.841 1.21 0.0404 0.0935 0.665 0.1769 1.04 0.867 1.25 0.0579 0.0929 0.533 0.2734 1.06 0.883 1.27 PRS_PLINK_0.001 471 Nasal polyps Both 779 8146 9 respiratory coral4 8146, 779 2037, 198 2036, 175 2036, 200 2037, 206 0.00856 0.0376 0.82 0.08617 1.01 0.937 1.09 -0.119 0.108 0.272 0.5657 0.888 0.718 1.1 0.0292 0.105 0.781 0.1072 1.03 0.838 1.26 0.0347 0.105 0.74 0.1306 1.04 0.843 1.27 PRS_PLINK_0.001 472 Chronic pharyngitis and nasopharyngitis Both 210 2436 9 respiratory coral4 2436, 210 609, 47 609, 44 609, 56 609, 63 0.0903 0.0719 0.21 0.6786 1.09 0.951 1.26 -0.055 0.214 0.797 0.09832 0.946 0.622 1.44 0.182 0.204 0.373 0.4285 1.2 0.804 1.79 0.279 0.201 0.165 0.7813 1.32 0.891 1.96 PRS_PLINK_0.001 473 Diseases of the larynx and vocal cords Both 432 6303 9 respiratory coral4 6303, 432 1576, 128 1576, 95 1575, 96 1576, 113 -0.0153 0.0498 0.759 0.1195 0.985 0.893 1.09 -0.299 0.14 0.0321 1.493 0.742 0.564 0.975 -0.287 0.139 0.0392 1.406 0.75 0.571 0.986 -0.12 0.134 0.371 0.4308 0.887 0.682 1.15 PRS_PLINK_0.001 473.1 Chronic laryngitis Both 18 266 9 respiratory coral4 266, 18 67, 3 66, 6 66, 4 67, 5 0.0865 0.217 0.69 0.1611 1.09 0.713 1.67 0.617 0.658 0.348 0.4579 1.85 0.51 6.74 0.295 0.71 0.678 0.169 1.34 0.334 5.4 0.627 0.686 0.36 0.4432 1.87 0.488 7.19 PRS_PLINK_0.001 473.3 Paralysis/spasm of vocal cords or larynx Both 37 662 9 respiratory coral4 662, 37 166, 14 165, 6 165, 7 166, 10 -0.141 0.172 0.411 0.3862 0.868 0.62 1.22 -0.825 0.463 0.0748 1.126 0.438 0.177 1.09 -0.75 0.463 0.105 0.9786 0.472 0.191 1.17 -0.332 0.407 0.414 0.3828 0.717 0.323 1.59 PRS_PLINK_0.001 473.4 Voice disturbance Both 201 2594 9 respiratory coral4 2594, 201 649, 62 648, 45 648, 44 649, 50 -0.0249 0.0729 0.733 0.135 0.975 0.846 1.13 -0.29 0.202 0.152 0.8196 0.749 0.504 1.11 -0.292 0.203 0.151 0.8204 0.747 0.502 1.11 -0.193 0.197 0.326 0.4863 0.824 0.56 1.21 PRS_PLINK_0.001 474 Acute and chronic tonsillitis Both 370 4514 9 respiratory coral4 4514, 370 1129, 96 1128, 102 1128, 93 1129, 79 -0.072 0.0535 0.178 0.7489 0.931 0.838 1.03 0.0617 0.148 0.677 0.1694 1.06 0.796 1.42 -0.0219 0.151 0.885 0.05324 0.978 0.728 1.32 -0.197 0.157 0.209 0.6792 0.821 0.604 1.12 PRS_PLINK_0.001 474.1 Acute tonsillitis Both 89 1432 9 respiratory coral4 1432, 89 358, 21 358, 25 358, 24 358, 19 -0.037 0.105 0.724 0.14 0.964 0.785 1.18 0.166 0.297 0.575 0.2402 1.18 0.66 2.11 0.129 0.3 0.667 0.1756 1.14 0.632 2.05 -0.097 0.315 0.758 0.1205 0.908 0.49 1.68 PRS_PLINK_0.001 474.2 Chronic tonsillitis and adenoiditis Both 262 2890 9 respiratory coral4 2890, 262 723, 68 722, 67 722, 71 723, 56 -0.0276 0.0634 0.663 0.1782 0.973 0.859 1.1 -0.0335 0.179 0.852 0.06977 0.967 0.68 1.37 0.0497 0.177 0.779 0.1086 1.05 0.743 1.49 -0.206 0.187 0.271 0.5663 0.814 0.564 1.17 PRS_PLINK_0.001 475 Chronic sinusitis Both 566 6725 9 respiratory coral4 6725, 566 1682, 131 1681, 143 1681, 150 1681, 142 0.0148 0.0432 0.732 0.1354 1.01 0.932 1.1 0.0919 0.125 0.464 0.3338 1.1 0.857 1.4 0.147 0.124 0.238 0.6243 1.16 0.908 1.48 0.0739 0.126 0.557 0.2544 1.08 0.842 1.38 PRS_PLINK_0.001 476 Allergic rhinitis Both 275 2818 9 respiratory coral4 2818, 275 705, 65 704, 72 704, 67 705, 71 0.0186 0.0631 0.768 0.1149 1.02 0.9 1.15 0.117 0.178 0.512 0.291 1.12 0.793 1.59 0.0656 0.181 0.717 0.1444 1.07 0.749 1.52 0.0754 0.179 0.674 0.1715 1.08 0.759 1.53 PRS_PLINK_0.001 477 Epistaxis or throat hemorrhage Both 425 6067 9 respiratory coral4 6067, 425 1516, 106 1517, 111 1516, 86 1517, 122 0.0292 0.0506 0.564 0.2491 1.03 0.932 1.14 0.0386 0.14 0.782 0.1066 1.04 0.79 1.37 -0.204 0.149 0.169 0.7711 0.815 0.609 1.09 0.147 0.138 0.286 0.5433 1.16 0.884 1.52 PRS_PLINK_0.001 478 Throat pain Both 75 988 9 respiratory coral4 988, 75 247, 18 247, 13 247, 28 247, 16 0.0423 0.119 0.723 0.141 1.04 0.826 1.32 -0.306 0.363 0.4 0.3975 0.737 0.361 1.5 0.421 0.31 0.174 0.7582 1.52 0.83 2.8 -0.0576 0.343 0.867 0.06209 0.944 0.482 1.85 PRS_PLINK_0.001 479 Other upper respiratory disease Both 830 10277 9 respiratory coral4 10277, 830 2570, 207 2569, 202 2569, 214 2569, 207 0.00457 0.0366 0.901 0.04537 1 0.935 1.08 -0.0237 0.103 0.817 0.08751 0.977 0.799 1.19 0.0427 0.102 0.675 0.1709 1.04 0.855 1.27 -0.0175 0.103 0.864 0.06329 0.983 0.804 1.2 PRS_PLINK_0.001 480 Pneumonia Both 1272 25655 9 respiratory coral4 25655, 1272 6414, 327 6414, 323 6413, 319 6414, 303 -0.00674 0.0289 0.816 0.08848 0.993 0.939 1.05 -0.00508 0.0803 0.95 0.02248 0.995 0.85 1.16 -0.0133 0.0807 0.869 0.06098 0.987 0.842 1.16 -0.0604 0.082 0.461 0.3362 0.941 0.802 1.11 PRS_PLINK_0.001 480.1 Bacterial pneumonia Both 853 16506 9 respiratory coral4 16506, 853 4127, 227 4126, 205 4126, 216 4127, 205 -0.00251 0.0353 0.943 0.02535 0.997 0.931 1.07 -0.0956 0.0986 0.332 0.4783 0.909 0.749 1.1 -0.0354 0.0976 0.717 0.1445 0.965 0.797 1.17 -0.0814 0.0991 0.412 0.3855 0.922 0.759 1.12 PRS_PLINK_0.001 480.11 Pneumococcal pneumonia Both 749 14643 9 respiratory coral4 14643, 749 3661, 202 3661, 182 3660, 184 3661, 181 -0.00369 0.0377 0.922 0.03525 0.996 0.925 1.07 -0.101 0.105 0.336 0.4732 0.904 0.737 1.11 -0.079 0.104 0.449 0.3474 0.924 0.753 1.13 -0.0898 0.105 0.394 0.4049 0.914 0.744 1.12 PRS_PLINK_0.001 480.12 Pseudomonal pneumonia Both 5 246 9 respiratory coral4 246, 5 62, 1 61, 2 61, 2 62, 0 -0.063 0.432 0.884 0.05347 0.939 0.402 2.19 0.345 0.835 0.679 0.1679 1.41 0.275 7.26 -0.191 1.06 0.857 0.06713 0.826 0.104 6.57 -1.09 1.08 0.315 0.502 0.337 0.0405 2.81 PRS_PLINK_0.001 480.2 Viral pneumonia Both 14 191 9 respiratory coral4 191, 14 48, 5 48, 2 47, 3 48, 4 -0.0166 0.253 0.948 0.0234 0.983 0.599 1.61 -0.802 0.75 0.285 0.5451 0.448 0.103 1.95 -0.0278 0.699 0.968 0.01401 0.973 0.247 3.82 -0.521 0.668 0.435 0.3613 0.594 0.16 2.2 PRS_PLINK_0.001 480.3 Pneumonia due to fungus (mycoses) Both 11 221 9 respiratory coral4 221, 11 56, 3 55, 2 55, 4 55, 2 0.405 0.327 0.216 0.6651 1.5 0.789 2.85 0.25 0.919 0.786 0.1047 1.28 0.212 7.77 0.14 0.756 0.853 0.06919 1.15 0.262 5.06 -0.0572 0.835 0.945 0.02437 0.944 0.184 4.85 PRS_PLINK_0.001 480.5 Bronchopneumonia and lung abscess Both 33 1959 9 respiratory coral4 1959, 33 490, 7 490, 12 489, 9 490, 5 -0.0458 0.164 0.78 0.1078 0.955 0.692 1.32 0.56 0.438 0.201 0.6964 1.75 0.742 4.13 0.176 0.461 0.703 0.1532 1.19 0.483 2.94 -0.455 0.517 0.379 0.4215 0.635 0.23 1.75 PRS_PLINK_0.001 481 Influenza Both 51 889 9 respiratory coral4 889, 51 223, 4 222, 14 222, 19 222, 14 0.342 0.152 0.0248 1.606 1.41 1.04 1.9 1.33 0.526 0.0112 1.95 3.79 1.35 10.6 1.55 0.516 0.0026 2.586 4.73 1.72 13 1.21 0.531 0.0228 1.642 3.35 1.18 9.48 PRS_PLINK_0.001 483 Acute bronchitis and bronchiolitis Both 36 503 9 respiratory coral4 503, 36 125, 8 126, 8 125, 9 126, 11 0.0522 0.169 0.757 0.1209 1.05 0.757 1.47 -0.05 0.484 0.918 0.03729 0.951 0.369 2.46 -0.0989 0.489 0.84 0.07597 0.906 0.348 2.36 0.174 0.459 0.704 0.1524 1.19 0.484 2.93 PRS_PLINK_0.001 495 Asthma Both 5240 65472 9 respiratory coral4 65472, 5240 16367, 1224 16368, 1353 16368, 1298 16368, 1365 0.0213 0.0144 0.14 0.8549 1.02 0.993 1.05 0.103 0.041 0.0123 1.91 1.11 1.02 1.2 0.0658 0.0415 0.113 0.9484 1.07 0.985 1.16 0.112 0.0411 0.00623 2.206 1.12 1.03 1.21 PRS_PLINK_0.001 495.2 Asthma with exacerbation Both 33 659 9 respiratory coral4 659, 33 165, 7 165, 11 164, 5 165, 10 0.0569 0.184 0.757 0.121 1.06 0.738 1.52 0.445 0.459 0.332 0.4788 1.56 0.635 3.83 -0.383 0.54 0.479 0.3198 0.682 0.237 1.97 0.508 0.476 0.286 0.5438 1.66 0.654 4.23 PRS_PLINK_0.001 496 Chronic airway obstruction Both 1148 25096 9 respiratory coral4 25096, 1148 6273, 270 6274, 277 6274, 290 6274, 311 0.0469 0.0305 0.124 0.9079 1.05 0.987 1.11 0.0271 0.0872 0.756 0.1214 1.03 0.866 1.22 0.0685 0.0864 0.428 0.3687 1.07 0.904 1.27 0.134 0.0852 0.115 0.938 1.14 0.968 1.35 PRS_PLINK_0.001 496.1 Emphysema Both 156 4213 9 respiratory coral4 4213, 156 1054, 34 1053, 42 1053, 39 1053, 41 0.0273 0.0827 0.741 0.1301 1.03 0.874 1.21 0.207 0.23 0.366 0.4365 1.23 0.785 1.93 0.138 0.234 0.556 0.2553 1.15 0.726 1.82 0.166 0.232 0.475 0.3236 1.18 0.749 1.86 PRS_PLINK_0.001 496.2 Chronic bronchitis Both 183 7090 9 respiratory coral4 7090, 183 1773, 40 1772, 41 1772, 55 1773, 47 0.12 0.0755 0.112 0.9492 1.13 0.972 1.31 0.0118 0.22 0.957 0.01899 1.01 0.657 1.56 0.304 0.208 0.143 0.844 1.35 0.902 2.04 0.108 0.216 0.616 0.2106 1.11 0.73 1.7 PRS_PLINK_0.001 496.21 Obstructive chronic bronchitis Both 158 6473 9 respiratory coral4 6473, 158 1619, 34 1618, 33 1618, 48 1618, 43 0.12 0.081 0.137 0.8617 1.13 0.962 1.32 -0.0607 0.241 0.801 0.0963 0.941 0.587 1.51 0.339 0.223 0.128 0.8922 1.4 0.907 2.17 0.171 0.229 0.455 0.3423 1.19 0.758 1.86 PRS_PLINK_0.001 496.3 Bronchiectasis Both 322 4580 9 respiratory coral4 4580, 322 1145, 71 1145, 77 1145, 90 1145, 84 0.0533 0.0586 0.362 0.4409 1.05 0.94 1.18 0.0904 0.168 0.591 0.2281 1.09 0.787 1.52 0.246 0.163 0.132 0.8787 1.28 0.928 1.76 0.175 0.166 0.293 0.5336 1.19 0.86 1.65 PRS_PLINK_0.001 497 Bronchitis Both 90 1554 9 respiratory coral4 1554, 90 389, 26 388, 23 388, 25 389, 16 -0.136 0.106 0.201 0.696 0.873 0.709 1.08 -0.0836 0.286 0.771 0.1132 0.92 0.525 1.61 -0.0319 0.283 0.91 0.04088 0.969 0.556 1.69 -0.39 0.316 0.217 0.6637 0.677 0.364 1.26 PRS_PLINK_0.001 500 Lung disease due to external agents Both 28 943 9 respiratory coral4 943, 28 236, 5 236, 9 235, 11 236, 3 -0.0492 0.179 0.783 0.106 0.952 0.67 1.35 0.573 0.5 0.252 0.5979 1.77 0.665 4.73 0.697 0.496 0.159 0.7974 2.01 0.76 5.31 -0.406 0.601 0.499 0.3017 0.666 0.205 2.16 PRS_PLINK_0.001 500.1 Extrinsic allergic alveolitis Both 7 185 9 respiratory coral4 185, 7 47, 2 46, 2 46, 1 46, 2 0.0369 0.364 0.919 0.03662 1.04 0.509 2.12 0.296 0.831 0.722 0.1416 1.34 0.264 6.85 -0.299 0.973 0.758 0.1201 0.741 0.11 4.99 0.312 0.801 0.697 0.1567 1.37 0.284 6.56 PRS_PLINK_0.001 500.2 Pneumoconiosis Both 13 531 9 respiratory coral4 531, 13 133, 1 133, 8 132, 3 133, 1 -0.184 0.241 0.446 0.351 0.832 0.518 1.33 1.72 0.786 0.0285 1.545 5.59 1.2 26.1 0.651 0.812 0.423 0.3737 1.92 0.39 9.42 -0.0143 0.842 0.986 0.005913 0.986 0.189 5.13 PRS_PLINK_0.001 501 Pneumonitis due to inhalation of food or vomitus Both 23 1654 9 respiratory coral4 1654, 23 414, 4 413, 10 413, 4 414, 5 0.0698 0.194 0.718 0.1437 1.07 0.734 1.57 0.863 0.519 0.0966 1.015 2.37 0.857 6.55 -0.0595 0.58 0.918 0.03698 0.942 0.302 2.94 0.205 0.565 0.717 0.1444 1.23 0.405 3.72 PRS_PLINK_0.001 502 Postinflammatory pulmonary fibrosis Both 80 2236 9 respiratory coral4 2236, 80 559, 17 559, 22 559, 21 559, 20 0.0278 0.114 0.807 0.09328 1.03 0.823 1.28 0.238 0.317 0.453 0.3437 1.27 0.681 2.36 0.226 0.318 0.477 0.3214 1.25 0.673 2.34 0.285 0.326 0.382 0.4184 1.33 0.702 2.52 PRS_PLINK_0.001 503 Pulmonary congestion and hypostasis Both 49 1229 9 respiratory coral4 1229, 49 308, 14 307, 8 307, 9 307, 18 0.0677 0.143 0.635 0.1969 1.07 0.809 1.42 -0.564 0.419 0.178 0.7498 0.569 0.25 1.29 -0.443 0.406 0.275 0.5602 0.642 0.29 1.42 0.28 0.348 0.421 0.3761 1.32 0.669 2.62 PRS_PLINK_0.001 504 Other alveolar and parietoalveolar pneumonopathy Both 31 804 9 respiratory coral4 804, 31 201, 7 201, 7 201, 9 201, 8 -0.00366 0.172 0.983 0.007435 0.996 0.711 1.4 0.0166 0.496 0.973 0.01178 1.02 0.385 2.69 0.317 0.482 0.511 0.2918 1.37 0.534 3.53 0.224 0.493 0.649 0.1875 1.25 0.476 3.29 PRS_PLINK_0.001 505 Other pulmonary inflamation or edema Both 10 163 9 respiratory coral4 163, 10 41, 3 41, 3 40, 2 41, 2 0.0696 0.311 0.823 0.08449 1.07 0.582 1.97 0.685 0.87 0.431 0.3658 1.98 0.361 10.9 -0.0611 0.851 0.943 0.02559 0.941 0.177 4.99 -0.0241 0.793 0.976 0.01067 0.976 0.206 4.62 PRS_PLINK_0.001 506 Empyema and pneumothorax Both 177 2879 9 respiratory coral4 2879, 177 720, 43 720, 44 719, 50 720, 40 0.0618 0.0774 0.425 0.3719 1.06 0.914 1.24 0.0608 0.218 0.78 0.1079 1.06 0.694 1.63 0.163 0.211 0.442 0.3548 1.18 0.777 1.78 -0.0473 0.224 0.832 0.07967 0.954 0.615 1.48 PRS_PLINK_0.001 507 Pleurisy; pleural effusion Both 751 15842 9 respiratory coral4 15842, 751 3961, 177 3960, 192 3960, 185 3961, 197 0.0361 0.0376 0.338 0.4712 1.04 0.963 1.12 0.0874 0.106 0.411 0.3866 1.09 0.886 1.34 0.0518 0.107 0.629 0.2015 1.05 0.854 1.3 0.133 0.106 0.212 0.6727 1.14 0.927 1.41 PRS_PLINK_0.001 508 Pulmonary collapse; interstitial and compensatory emphysema Both 263 5027 9 respiratory coral4 5027, 263 1257, 62 1257, 64 1256, 75 1257, 62 0.00692 0.0641 0.914 0.03903 1.01 0.888 1.14 0.0409 0.18 0.821 0.0859 1.04 0.732 1.48 0.234 0.175 0.182 0.7388 1.26 0.896 1.78 0.0636 0.183 0.728 0.1379 1.07 0.745 1.52 PRS_PLINK_0.001 509 Respiratory failure, insufficiency, arrest Both 175 6488 9 respiratory coral4 6488, 175 1622, 52 1622, 42 1622, 41 1622, 40 -0.0912 0.0748 0.223 0.6522 0.913 0.788 1.06 -0.204 0.207 0.325 0.4887 0.816 0.544 1.22 -0.229 0.208 0.272 0.566 0.795 0.529 1.2 -0.3 0.21 0.154 0.8117 0.741 0.49 1.12 PRS_PLINK_0.001 509.1 Respiratory failure Both 116 5174 9 respiratory coral4 5174, 116 1294, 31 1293, 31 1293, 28 1294, 26 -0.0472 0.0915 0.606 0.2174 0.954 0.797 1.14 -0.0187 0.25 0.941 0.02661 0.982 0.601 1.6 -0.0984 0.256 0.701 0.1544 0.906 0.549 1.5 -0.212 0.262 0.418 0.3784 0.809 0.484 1.35 PRS_PLINK_0.001 509.2 Respiratory insufficiency Both 102 4515 9 respiratory coral4 4515, 102 1129, 29 1129, 25 1128, 23 1129, 25 -0.0515 0.0974 0.597 0.2241 0.95 0.785 1.15 -0.168 0.268 0.531 0.2753 0.845 0.5 1.43 -0.229 0.274 0.403 0.3947 0.795 0.465 1.36 -0.211 0.269 0.433 0.3638 0.81 0.478 1.37 PRS_PLINK_0.001 509.5 Respiratory arrest Both 11 356 9 respiratory coral4 356, 11 89, 4 89, 3 89, 1 89, 3 -0.0932 0.266 0.726 0.1388 0.911 0.54 1.54 -0.107 0.675 0.874 0.0586 0.898 0.239 3.37 -0.628 0.817 0.442 0.3546 0.534 0.108 2.65 -0.214 0.67 0.75 0.1252 0.807 0.217 3 PRS_PLINK_0.001 509.8 Dependence on respirator [Ventilator] or supplemental oxygen Both 48 957 9 respiratory coral4 957, 48 240, 17 239, 10 239, 12 239, 9 -0.214 0.144 0.136 0.868 0.807 0.609 1.07 -0.48 0.385 0.213 0.6718 0.619 0.291 1.32 -0.367 0.37 0.321 0.4933 0.693 0.336 1.43 -0.624 0.398 0.117 0.9324 0.536 0.245 1.17 PRS_PLINK_0.001 510 Other diseases of lung Both 95 1836 9 respiratory coral4 1836, 95 459, 22 459, 21 459, 27 459, 25 0.0438 0.102 0.667 0.1757 1.04 0.856 1.28 -0.0824 0.303 0.785 0.1049 0.921 0.509 1.67 0.202 0.287 0.482 0.3166 1.22 0.697 2.15 0.151 0.291 0.603 0.22 1.16 0.658 2.06 PRS_PLINK_0.001 512 Other symptoms of respiratory system Both 1404 22647 9 respiratory coral4 22647, 1404 5662, 350 5662, 330 5661, 355 5662, 369 0.0142 0.0277 0.608 0.2159 1.01 0.961 1.07 -0.0524 0.079 0.507 0.2949 0.949 0.813 1.11 0.0318 0.0778 0.683 0.1656 1.03 0.886 1.2 0.0663 0.0773 0.391 0.4076 1.07 0.918 1.24 PRS_PLINK_0.001 512.1 Wheezing Both 26 554 9 respiratory coral4 554, 26 139, 7 138, 6 138, 7 139, 6 -0.0247 0.182 0.892 0.04953 0.976 0.683 1.39 -0.0676 0.521 0.897 0.04725 0.935 0.336 2.6 -0.014 0.508 0.978 0.00962 0.986 0.364 2.67 -0.0937 0.534 0.861 0.06511 0.911 0.32 2.59 PRS_PLINK_0.001 512.2 Painful respiration Both 35 515 9 respiratory coral4 515, 35 129, 8 129, 9 128, 11 129, 7 -0.0867 0.163 0.595 0.2252 0.917 0.666 1.26 0.248 0.469 0.597 0.2237 1.28 0.511 3.22 0.445 0.458 0.332 0.4794 1.56 0.636 3.83 -0.141 0.492 0.774 0.1112 0.868 0.331 2.28 PRS_PLINK_0.001 512.7 Shortness of breath Both 834 14566 9 respiratory coral4 14566, 834 3642, 203 3641, 192 3641, 216 3642, 223 0.0264 0.0359 0.463 0.3341 1.03 0.957 1.1 -0.0507 0.103 0.623 0.2057 0.951 0.777 1.16 0.0732 0.101 0.466 0.3314 1.08 0.884 1.31 0.0993 0.1 0.321 0.4936 1.1 0.908 1.34 PRS_PLINK_0.001 512.8 Cough Both 483 7242 9 respiratory coral4 7242, 483 1811, 129 1810, 106 1810, 125 1811, 123 -0.000514 0.0469 0.991 0.003815 0.999 0.912 1.1 -0.189 0.135 0.162 0.7908 0.828 0.636 1.08 -0.0103 0.13 0.936 0.02851 0.99 0.768 1.28 -0.036 0.131 0.783 0.1063 0.965 0.747 1.25 PRS_PLINK_0.001 512.9 Other dyspnea Both 146 2185 9 respiratory coral4 2185, 146 547, 37 546, 41 546, 35 546, 33 -0.02 0.0864 0.817 0.08788 0.98 0.827 1.16 0.107 0.231 0.643 0.1915 1.11 0.708 1.75 -0.0391 0.24 0.87 0.06027 0.962 0.601 1.54 -0.108 0.243 0.657 0.1822 0.898 0.557 1.45 PRS_PLINK_0.001 513 Respiratory abnormalities Both 92 1495 9 respiratory coral4 1495, 92 374, 19 374, 27 373, 24 374, 22 0.0366 0.105 0.727 0.1386 1.04 0.845 1.27 0.352 0.303 0.245 0.6103 1.42 0.785 2.57 0.2 0.305 0.512 0.2904 1.22 0.671 2.22 0.12 0.313 0.701 0.1541 1.13 0.611 2.08 PRS_PLINK_0.001 513.3 Hypoventilation Both 11 209 9 respiratory coral4 209, 11 53, 3 52, 4 52, 1 52, 3 0.042 0.282 0.882 0.05456 1.04 0.599 1.81 0.21 0.679 0.757 0.1208 1.23 0.326 4.67 -0.89 0.86 0.301 0.522 0.41 0.0761 2.22 -0.0547 0.703 0.938 0.02784 0.947 0.239 3.75 PRS_PLINK_0.001 513.4 Hyperventilation Both 39 716 9 respiratory coral4 716, 39 179, 9 179, 12 179, 10 179, 8 -0.0487 0.155 0.753 0.1234 0.952 0.703 1.29 0.228 0.433 0.598 0.2231 1.26 0.538 2.94 -0.00191 0.446 0.997 0.001488 0.998 0.416 2.39 -0.207 0.468 0.659 0.1811 0.813 0.325 2.04 PRS_PLINK_0.001 513.8 Disorders of diaphragm Both 24 416 9 respiratory coral4 416, 24 104, 4 104, 6 104, 9 104, 5 0.0925 0.19 0.627 0.2027 1.1 0.755 1.59 0.576 0.601 0.337 0.4718 1.78 0.548 5.78 0.78 0.554 0.159 0.7987 2.18 0.737 6.46 0.06 0.638 0.925 0.03381 1.06 0.304 3.71 PRS_PLINK_0.001 514 Abnormal findings examination of lungs Both 304 5987 9 respiratory coral4 5987, 304 1497, 75 1497, 74 1496, 82 1497, 73 -0.000797 0.0588 0.989 0.004725 0.999 0.89 1.12 -0.0334 0.167 0.841 0.07515 0.967 0.698 1.34 0.0946 0.163 0.562 0.2502 1.1 0.798 1.51 -0.0209 0.168 0.901 0.04515 0.979 0.704 1.36 PRS_PLINK_0.001 516 Abnormal sputum Both 274 5164 9 respiratory coral4 5164, 274 1291, 59 1291, 63 1291, 75 1291, 77 0.0675 0.0627 0.282 0.5502 1.07 0.946 1.21 0.0601 0.183 0.743 0.1292 1.06 0.742 1.52 0.225 0.177 0.203 0.6923 1.25 0.885 1.77 0.267 0.177 0.131 0.8819 1.31 0.923 1.85 PRS_PLINK_0.001 516.1 Hemoptysis Both 271 5021 9 respiratory coral4 5021, 271 1256, 60 1255, 62 1255, 75 1255, 74 0.0579 0.0631 0.359 0.4446 1.06 0.936 1.2 0.0368 0.183 0.841 0.07529 1.04 0.724 1.49 0.207 0.176 0.242 0.6171 1.23 0.87 1.74 0.212 0.178 0.233 0.632 1.24 0.872 1.75 PRS_PLINK_0.001 519 Other diseases of respiratory system, not elsewhere classified Both 1246 23357 9 respiratory coral4 23357, 1246 5839, 286 5839, 317 5839, 349 5839, 294 0.00672 0.0292 0.818 0.08725 1.01 0.951 1.07 0.106 0.0835 0.206 0.6863 1.11 0.944 1.31 0.205 0.082 0.0124 1.908 1.23 1.05 1.44 0.0267 0.0854 0.754 0.1225 1.03 0.869 1.21 PRS_PLINK_0.001 519.2 Respiratory complications Both 33 832 9 respiratory coral4 832, 33 208, 11 208, 7 208, 10 208, 5 -0.145 0.162 0.372 0.4294 0.865 0.63 1.19 -0.4 0.457 0.381 0.4188 0.67 0.273 1.64 0.0314 0.431 0.942 0.02594 1.03 0.443 2.4 -0.693 0.513 0.177 0.7526 0.5 0.183 1.37 PRS_PLINK_0.001 519.8 Other diseases of respiratory system, NEC Both 1162 22004 9 respiratory coral4 22004, 1162 5500, 268 5501, 296 5501, 325 5501, 273 0.00717 0.0303 0.813 0.08997 1.01 0.949 1.07 0.105 0.0863 0.226 0.6461 1.11 0.937 1.31 0.202 0.0848 0.017 1.769 1.22 1.04 1.45 0.0239 0.0884 0.787 0.1041 1.02 0.861 1.22 PRS_PLINK_0.001 519.9 Symptoms involving respiratory system and other chest symptoms Both 51 773 9 respiratory coral4 773, 51 194, 14 193, 8 193, 14 193, 15 -0.071 0.147 0.628 0.202 0.931 0.699 1.24 -0.575 0.425 0.177 0.7529 0.563 0.245 1.3 -0.0333 0.377 0.93 0.03169 0.967 0.462 2.03 0.00154 0.376 0.997 0.001419 1 0.479 2.09 PRS_PLINK_0.001 520 Disorders of tooth development Both 522 5331 10 digestive chartreuse4 5331, 522 1333, 124 1333, 116 1332, 162 1333, 120 0.00602 0.0465 0.897 0.04719 1.01 0.918 1.1 -0.0573 0.134 0.67 0.1742 0.944 0.726 1.23 0.268 0.125 0.0328 1.484 1.31 1.02 1.67 -0.0322 0.134 0.81 0.09166 0.968 0.745 1.26 PRS_PLINK_0.001 520.1 Hereditary disturbances in tooth structure Both 14 130 10 digestive chartreuse4 130, 14 33, 5 32, 4 32, 1 33, 4 -0.136 0.275 0.622 0.2064 0.873 0.509 1.5 0.205 0.737 0.78 0.1077 1.23 0.29 5.2 -1.07 0.945 0.259 0.5873 0.344 0.0539 2.19 0.0873 0.742 0.906 0.04271 1.09 0.255 4.67 PRS_PLINK_0.001 520.2 Disturbances in tooth eruption Both 602 6111 10 digestive chartreuse4 6111, 602 1528, 135 1528, 140 1527, 184 1528, 143 0.0258 0.043 0.548 0.2611 1.03 0.943 1.12 0.0466 0.125 0.711 0.1484 1.05 0.819 1.34 0.312 0.119 0.00875 2.058 1.37 1.08 1.72 0.0638 0.126 0.612 0.213 1.07 0.833 1.36 PRS_PLINK_0.001 521 Diseases of hard tissues of teeth Both 622 7983 10 digestive chartreuse4 7983, 622 1996, 163 1996, 150 1995, 141 1996, 168 0.0303 0.0416 0.466 0.3315 1.03 0.95 1.12 -0.0728 0.117 0.534 0.2723 0.93 0.739 1.17 -0.134 0.119 0.262 0.5818 0.875 0.693 1.11 0.0396 0.115 0.73 0.1366 1.04 0.831 1.3 PRS_PLINK_0.001 521.1 Dental caries Both 621 7988 10 digestive chartreuse4 7988, 621 1997, 161 1997, 149 1997, 143 1997, 168 0.0344 0.0417 0.41 0.3876 1.04 0.954 1.12 -0.0701 0.118 0.551 0.2587 0.932 0.74 1.17 -0.111 0.119 0.351 0.4544 0.895 0.709 1.13 0.0511 0.115 0.657 0.1826 1.05 0.84 1.32 PRS_PLINK_0.001 522 Diseases of pulp and periapical tissues Both 411 4647 10 digestive chartreuse4 4647, 411 1162, 106 1162, 92 1161, 103 1162, 110 0.00848 0.0519 0.87 0.0604 1.01 0.911 1.12 -0.123 0.148 0.406 0.3912 0.884 0.661 1.18 -0.0205 0.144 0.887 0.05191 0.98 0.738 1.3 0.0571 0.143 0.688 0.1621 1.06 0.801 1.4 PRS_PLINK_0.001 522.5 Periapical abscess Both 266 3088 10 digestive chartreuse4 3088, 266 772, 68 772, 56 772, 71 772, 71 0.022 0.0633 0.728 0.1379 1.02 0.903 1.16 -0.181 0.187 0.332 0.4786 0.834 0.578 1.2 0.0533 0.177 0.763 0.1174 1.05 0.746 1.49 0.0697 0.177 0.694 0.1588 1.07 0.758 1.52 PRS_PLINK_0.001 523 Gingival and periodontal diseases Both 379 4424 10 digestive chartreuse4 4424, 379 1106, 94 1106, 95 1106, 103 1106, 87 -0.0463 0.053 0.383 0.4166 0.955 0.861 1.06 0.0105 0.151 0.945 0.02473 1.01 0.752 1.36 0.111 0.148 0.453 0.3437 1.12 0.836 1.5 -0.0708 0.155 0.647 0.1889 0.932 0.688 1.26 PRS_PLINK_0.001 523.1 Gingivitis Both 24 290 10 digestive chartreuse4 290, 24 73, 3 72, 7 72, 5 73, 9 0.266 0.198 0.179 0.748 1.3 0.885 1.92 0.854 0.654 0.191 0.7183 2.35 0.653 8.46 0.621 0.697 0.373 0.4279 1.86 0.474 7.29 0.678 0.652 0.298 0.5252 1.97 0.549 7.07 PRS_PLINK_0.001 523.3 Periodontitis (acute or chronic) Both 281 3118 10 digestive chartreuse4 3118, 281 780, 70 779, 73 779, 70 780, 68 -0.0505 0.0616 0.413 0.3844 0.951 0.843 1.07 0.0464 0.174 0.789 0.1028 1.05 0.745 1.47 0.0177 0.175 0.919 0.03652 1.02 0.722 1.44 -0.0101 0.177 0.955 0.02018 0.99 0.699 1.4 PRS_PLINK_0.001 523.31 Acute periodontitis Both 153 1807 10 digestive chartreuse4 1807, 153 452, 39 452, 38 451, 41 452, 35 -0.032 0.081 0.693 0.1595 0.969 0.826 1.14 0.00637 0.234 0.978 0.009538 1.01 0.636 1.59 0.0712 0.232 0.758 0.1201 1.07 0.682 1.69 -0.083 0.24 0.73 0.1367 0.92 0.575 1.47 PRS_PLINK_0.001 523.32 Chronic periodontitis Both 143 1470 10 digestive chartreuse4 1470, 143 368, 39 367, 39 367, 32 368, 33 -0.144 0.0893 0.107 0.9708 0.866 0.727 1.03 -0.0491 0.237 0.836 0.07786 0.952 0.598 1.52 -0.209 0.247 0.397 0.4017 0.811 0.5 1.32 -0.16 0.245 0.516 0.2876 0.853 0.527 1.38 PRS_PLINK_0.001 524 Dentofacial anomalies, including malocclusion Both 79 881 10 digestive chartreuse4 881, 79 221, 24 220, 19 220, 25 220, 11 -0.192 0.112 0.0864 1.064 0.825 0.663 1.03 -0.273 0.316 0.388 0.4112 0.761 0.41 1.41 0.0732 0.302 0.809 0.0922 1.08 0.595 1.95 -0.759 0.368 0.0394 1.405 0.468 0.227 0.964 PRS_PLINK_0.001 524.3 Anomalies of tooth position/malocclusion Both 77 793 10 digestive chartreuse4 793, 77 199, 20 198, 21 198, 25 198, 11 -0.176 0.115 0.127 0.8971 0.839 0.669 1.05 0.0257 0.322 0.936 0.02857 1.03 0.546 1.93 0.192 0.314 0.542 0.2662 1.21 0.654 2.24 -0.549 0.383 0.151 0.8209 0.577 0.273 1.22 PRS_PLINK_0.001 525 Other diseases of the teeth and supporting structures Both 545 6749 10 digestive chartreuse4 6749, 545 1688, 137 1687, 137 1687, 143 1687, 128 -0.0196 0.0442 0.657 0.1825 0.981 0.899 1.07 0.00564 0.125 0.964 0.0159 1.01 0.787 1.29 0.0491 0.124 0.692 0.1597 1.05 0.824 1.34 -0.0505 0.128 0.693 0.1594 0.951 0.74 1.22 PRS_PLINK_0.001 525.2 Atrophy of edentulous alveolar ridge Both 14 186 10 digestive chartreuse4 186, 14 47, 6 46, 1 46, 4 47, 3 0.0458 0.255 0.858 0.06674 1.05 0.635 1.73 -1.44 0.854 0.0912 1.04 0.236 0.0443 1.26 -0.194 0.637 0.761 0.1186 0.824 0.237 2.87 -0.407 0.66 0.538 0.2694 0.666 0.183 2.43 PRS_PLINK_0.001 526 Diseases of the jaws Both 203 2461 10 digestive chartreuse4 2461, 203 616, 56 615, 56 615, 49 615, 42 -0.127 0.074 0.0862 1.065 0.881 0.762 1.02 0.0192 0.195 0.922 0.03532 1.02 0.695 1.49 -0.113 0.201 0.575 0.24 0.893 0.602 1.33 -0.245 0.21 0.245 0.6114 0.783 0.519 1.18 PRS_PLINK_0.001 526.1 Cysts of the jaws Both 94 853 10 digestive chartreuse4 853, 94 214, 17 213, 29 213, 24 213, 24 0.0458 0.113 0.686 0.1639 1.05 0.839 1.31 0.535 0.312 0.0867 1.062 1.71 0.926 3.15 0.324 0.324 0.318 0.498 1.38 0.732 2.61 0.359 0.326 0.271 0.567 1.43 0.756 2.71 PRS_PLINK_0.001 526.3 Anomalies of jaw size/symmetry Both 13 177 10 digestive chartreuse4 177, 13 45, 4 44, 6 44, 1 44, 2 -0.54 0.284 0.0576 1.24 0.583 0.334 1.02 -0.0524 0.669 0.938 0.02798 0.949 0.256 3.52 -1.43 0.941 0.129 0.8884 0.24 0.0379 1.52 -1.28 0.932 0.169 0.7718 0.277 0.0446 1.73 PRS_PLINK_0.001 526.4 Temporomandibular joint disorders Both 47 636 10 digestive chartreuse4 636, 47 159, 16 159, 15 159, 8 159, 8 -0.364 0.154 0.0177 1.751 0.695 0.514 0.939 -0.0501 0.369 0.892 0.04963 0.951 0.462 1.96 -0.588 0.422 0.163 0.7876 0.555 0.243 1.27 -0.587 0.425 0.166 0.7788 0.556 0.242 1.28 PRS_PLINK_0.001 526.41 Temporomandibular joint disorder, unspecified Both 47 618 10 digestive chartreuse4 618, 47 155, 16 154, 15 154, 8 155, 8 -0.373 0.153 0.015 1.823 0.689 0.51 0.93 -0.0503 0.367 0.891 0.05012 0.951 0.463 1.95 -0.585 0.422 0.166 0.7797 0.557 0.243 1.27 -0.593 0.429 0.166 0.7796 0.552 0.239 1.28 PRS_PLINK_0.001 526.5 Inflammatory conditions of jaw Both 22 295 10 digestive chartreuse4 295, 22 74, 7 74, 6 73, 6 74, 3 -0.173 0.208 0.405 0.3927 0.841 0.559 1.26 -0.158 0.541 0.77 0.1135 0.854 0.296 2.46 0.11 0.567 0.846 0.07258 1.12 0.367 3.39 -0.615 0.632 0.33 0.4817 0.54 0.157 1.86 PRS_PLINK_0.001 526.9 Jaw disease NOS Both 34 573 10 digestive chartreuse4 573, 34 144, 9 143, 10 143, 7 143, 8 -0.0311 0.177 0.861 0.06522 0.969 0.685 1.37 0.132 0.448 0.769 0.1142 1.14 0.474 2.75 -0.201 0.479 0.674 0.171 0.818 0.32 2.09 -0.143 0.47 0.761 0.1187 0.867 0.345 2.18 PRS_PLINK_0.001 527 Diseases of the salivary glands Both 132 1818 10 digestive chartreuse4 1818, 132 455, 35 454, 39 454, 32 455, 26 -0.0857 0.0893 0.337 0.4725 0.918 0.771 1.09 0.0926 0.239 0.698 0.1559 1.1 0.687 1.75 -0.103 0.25 0.679 0.1682 0.902 0.553 1.47 -0.31 0.264 0.24 0.6202 0.733 0.437 1.23 PRS_PLINK_0.001 527.1 Hypertrophy of salivary gland Both 18 228 10 digestive chartreuse4 228, 18 57, 2 57, 5 57, 5 57, 6 0.249 0.265 0.346 0.4605 1.28 0.764 2.16 0.17 0.729 0.815 0.08867 1.19 0.284 4.95 0.104 0.745 0.889 0.05105 1.11 0.258 4.78 1.18 0.73 0.106 0.9739 3.25 0.778 13.6 PRS_PLINK_0.001 527.2 Sialoadenitis Both 74 929 10 digestive chartreuse4 929, 74 233, 22 232, 32 232, 15 232, 5 -0.249 0.116 0.0322 1.492 0.779 0.62 0.979 0.378 0.286 0.186 0.73 1.46 0.833 2.55 -0.386 0.336 0.25 0.6017 0.679 0.352 1.31 -1.36 0.463 0.0033 2.481 0.256 0.103 0.636 PRS_PLINK_0.001 527.7 Disturbance of salivary secretion Both 11 175 10 digestive chartreuse4 175, 11 44, 5 44, 2 43, 2 44, 2 -0.11 0.248 0.658 0.182 0.896 0.551 1.46 -0.616 0.738 0.404 0.3938 0.54 0.127 2.29 -0.625 0.727 0.39 0.4094 0.535 0.129 2.22 -0.895 0.754 0.236 0.6278 0.409 0.0932 1.79 PRS_PLINK_0.001 527.8 Other specified diseases of the salivary glands Both 27 288 10 digestive chartreuse4 288, 27 72, 3 72, 8 72, 5 72, 11 0.274 0.2 0.169 0.7717 1.32 0.89 1.95 0.658 0.613 0.283 0.5481 1.93 0.581 6.42 0.257 0.647 0.692 0.1602 1.29 0.364 4.59 1.24 0.602 0.0397 1.401 3.45 1.06 11.2 PRS_PLINK_0.001 528 Diseases of the oral soft tissues, excluding lesions specific for gingiva and tongue Both 798 10115 10 digestive chartreuse4 10115, 798 2529, 205 2529, 200 2528, 189 2529, 204 0.00245 0.0368 0.947 0.02369 1 0.933 1.08 -0.0238 0.103 0.817 0.08786 0.976 0.798 1.19 -0.0876 0.105 0.402 0.3955 0.916 0.746 1.12 -0.00937 0.103 0.927 0.03272 0.991 0.81 1.21 PRS_PLINK_0.001 528.1 Stomatitis and mucositis Both 64 1231 10 digestive chartreuse4 1231, 64 308, 17 308, 21 307, 13 308, 13 -0.146 0.131 0.267 0.5742 0.864 0.668 1.12 0.24 0.323 0.458 0.3394 1.27 0.675 2.4 -0.234 0.359 0.514 0.2886 0.791 0.392 1.6 -0.258 0.358 0.471 0.3274 0.773 0.383 1.56 PRS_PLINK_0.001 528.11 Stomatitis and mucositis (ulcerative) Both 53 1020 10 digestive chartreuse4 1020, 53 255, 16 255, 14 255, 11 255, 12 -0.142 0.142 0.316 0.5 0.868 0.657 1.15 -0.0625 0.36 0.862 0.06444 0.939 0.464 1.9 -0.318 0.381 0.404 0.3936 0.728 0.345 1.54 -0.26 0.374 0.487 0.3125 0.771 0.371 1.6 PRS_PLINK_0.001 528.12 Oral aphthae Both 12 212 10 digestive chartreuse4 212, 12 53, 3 53, 5 53, 2 53, 2 -0.187 0.3 0.532 0.2739 0.829 0.461 1.49 0.373 0.642 0.562 0.2504 1.45 0.412 5.11 -0.486 0.752 0.518 0.2854 0.615 0.141 2.69 -0.456 0.777 0.557 0.2539 0.634 0.138 2.91 PRS_PLINK_0.001 528.3 Cellulitis and abscess of oral soft tissues Both 43 467 10 digestive chartreuse4 467, 43 117, 12 117, 9 116, 11 117, 11 0.0496 0.153 0.746 0.1275 1.05 0.779 1.42 -0.145 0.442 0.742 0.1294 0.865 0.364 2.05 0.0272 0.423 0.949 0.02286 1.03 0.449 2.35 0.0535 0.423 0.899 0.04606 1.05 0.461 2.42 PRS_PLINK_0.001 528.4 Cysts of oral soft tissues Both 31 345 10 digestive chartreuse4 345, 31 87, 8 86, 8 86, 7 86, 8 0.119 0.181 0.511 0.2917 1.13 0.79 1.61 0.0999 0.49 0.838 0.07654 1.11 0.423 2.89 -0.226 0.507 0.655 0.1837 0.798 0.296 2.15 0.0786 0.486 0.872 0.05971 1.08 0.417 2.81 PRS_PLINK_0.001 528.41 Cyst of the salivary gland Both 25 259 10 digestive chartreuse4 259, 25 65, 5 65, 6 64, 6 65, 8 0.229 0.197 0.246 0.6089 1.26 0.854 1.85 0.404 0.594 0.496 0.3044 1.5 0.468 4.8 0.227 0.596 0.703 0.1528 1.25 0.39 4.04 0.433 0.546 0.428 0.3689 1.54 0.529 4.49 PRS_PLINK_0.001 528.5 Diseases of lips Both 141 1806 10 digestive chartreuse4 1806, 141 452, 42 451, 28 451, 46 452, 25 -0.097 0.0852 0.255 0.5936 0.908 0.768 1.07 -0.359 0.248 0.148 0.8294 0.698 0.429 1.14 0.132 0.222 0.551 0.2589 1.14 0.739 1.76 -0.491 0.257 0.0562 1.25 0.612 0.37 1.01 PRS_PLINK_0.001 528.6 Leukoplakia of oral mucosa Both 66 736 10 digestive chartreuse4 736, 66 184, 15 184, 14 184, 15 184, 22 0.175 0.127 0.167 0.776 1.19 0.929 1.53 -0.12 0.37 0.745 0.1278 0.887 0.429 1.83 -0.0287 0.37 0.938 0.02766 0.972 0.47 2.01 0.366 0.341 0.283 0.5479 1.44 0.739 2.82 PRS_PLINK_0.001 528.7 Sialolithiasis Both 64 802 10 digestive chartreuse4 802, 64 201, 11 200, 17 200, 19 201, 17 0.144 0.127 0.256 0.5923 1.15 0.901 1.48 0.452 0.386 0.242 0.6171 1.57 0.737 3.35 0.598 0.379 0.115 0.9399 1.82 0.865 3.82 0.382 0.385 0.321 0.4931 1.47 0.689 3.12 PRS_PLINK_0.001 529 Diseases and other conditions of the tongue Both 223 3163 10 digestive chartreuse4 3163, 223 791, 48 791, 48 790, 76 791, 51 0.0735 0.0699 0.293 0.5325 1.08 0.938 1.23 0.00075 0.207 0.997 0.001256 1 0.667 1.5 0.461 0.19 0.0154 1.814 1.59 1.09 2.3 0.0871 0.206 0.672 0.1724 1.09 0.729 1.63 PRS_PLINK_0.001 529.1 Glossitis Both 41 773 10 digestive chartreuse4 773, 41 194, 9 193, 3 193, 18 193, 11 0.172 0.16 0.282 0.5491 1.19 0.868 1.62 -0.92 0.582 0.114 0.9424 0.399 0.127 1.25 0.602 0.401 0.133 0.8759 1.83 0.832 4.01 0.284 0.44 0.518 0.2858 1.33 0.561 3.15 PRS_PLINK_0.001 530 Diseases of esophagus Both 6342 73619 10 digestive chartreuse4 73619, 6342 18404, 1589 18405, 1578 18404, 1572 18405, 1603 -0.00441 0.0131 0.737 0.1325 0.996 0.97 1.02 -0.0129 0.0371 0.728 0.138 0.987 0.918 1.06 -0.0197 0.0372 0.597 0.2238 0.981 0.912 1.05 -0.0068 0.0371 0.855 0.06819 0.993 0.923 1.07 PRS_PLINK_0.001 530.1 Esophagitis, GERD and related diseases Both 5971 71739 10 digestive chartreuse4 71739, 5971 17934, 1494 17935, 1506 17934, 1470 17935, 1501 -0.00589 0.0135 0.663 0.1782 0.994 0.968 1.02 0.00305 0.0381 0.936 0.02864 1 0.931 1.08 -0.0236 0.0384 0.538 0.2693 0.977 0.906 1.05 -0.00795 0.0383 0.835 0.07808 0.992 0.92 1.07 PRS_PLINK_0.001 530.11 GERD Both 4454 58697 10 digestive chartreuse4 58697, 4454 14674, 1138 14674, 1137 14674, 1104 14674, 1075 -0.0221 0.0156 0.156 0.8078 0.978 0.949 1.01 0.000186 0.0436 0.997 0.001484 1 0.918 1.09 -0.0289 0.0439 0.51 0.2922 0.971 0.891 1.06 -0.0559 0.0443 0.207 0.6845 0.946 0.867 1.03 PRS_PLINK_0.001 530.12 Ulcer of esophagus Both 887 13200 10 digestive chartreuse4 13200, 887 3300, 240 3300, 202 3300, 193 3300, 252 0.00487 0.0354 0.891 0.05033 1 0.938 1.08 -0.168 0.0984 0.0876 1.057 0.845 0.697 1.03 -0.203 0.0997 0.0419 1.378 0.816 0.671 0.993 0.0524 0.0937 0.576 0.2393 1.05 0.877 1.27 PRS_PLINK_0.001 530.14 Reflux esophagitis Both 2130 26891 10 digestive chartreuse4 26891, 2130 6723, 513 6723, 539 6722, 554 6723, 524 0.0095 0.0225 0.673 0.1721 1.01 0.966 1.06 0.0549 0.0641 0.392 0.407 1.06 0.932 1.2 0.0902 0.0638 0.157 0.8028 1.09 0.966 1.24 0.0281 0.0647 0.664 0.1777 1.03 0.906 1.17 PRS_PLINK_0.001 530.2 Esophageal bleeding (varices/hemorrhage) Both 232 4307 10 digestive chartreuse4 4307, 232 1077, 62 1077, 57 1076, 57 1077, 56 -0.0159 0.0669 0.811 0.09072 0.984 0.863 1.12 -0.0833 0.186 0.654 0.1844 0.92 0.639 1.32 -0.0735 0.186 0.693 0.1592 0.929 0.645 1.34 -0.0953 0.188 0.612 0.2129 0.909 0.629 1.31 PRS_PLINK_0.001 530.3 Stricture and stenosis of esophagus Both 355 4713 10 digestive chartreuse4 4713, 355 1179, 85 1178, 83 1178, 96 1178, 91 0.0331 0.0548 0.546 0.263 1.03 0.928 1.15 -0.0202 0.158 0.898 0.04651 0.98 0.718 1.34 0.127 0.154 0.408 0.3898 1.14 0.84 1.54 0.0711 0.156 0.649 0.1881 1.07 0.791 1.46 PRS_PLINK_0.001 530.5 Disorders of esophageal motility Both 136 1642 10 digestive chartreuse4 1642, 136 411, 42 410, 35 410, 32 411, 27 -0.154 0.0857 0.0714 1.146 0.857 0.724 1.01 -0.198 0.237 0.404 0.3939 0.821 0.516 1.31 -0.233 0.242 0.335 0.4749 0.792 0.493 1.27 -0.443 0.252 0.0787 1.104 0.642 0.392 1.05 PRS_PLINK_0.001 530.6 Diverticulum of esophagus, acquired Both 29 367 10 digestive chartreuse4 367, 29 92, 8 92, 3 91, 10 92, 8 0.0247 0.191 0.898 0.04696 1.02 0.704 1.49 -0.992 0.609 0.103 0.9864 0.371 0.112 1.22 0.149 0.482 0.757 0.1207 1.16 0.451 2.99 0.0269 0.489 0.956 0.01945 1.03 0.394 2.68 PRS_PLINK_0.001 530.7 Gastroesophageal laceration-hemorrhage syndrome Both 47 825 10 digestive chartreuse4 825, 47 207, 8 206, 10 206, 15 206, 14 0.138 0.148 0.349 0.4576 1.15 0.86 1.53 0.159 0.445 0.721 0.1422 1.17 0.49 2.81 0.577 0.422 0.172 0.7652 1.78 0.778 4.07 0.511 0.424 0.228 0.642 1.67 0.726 3.82 PRS_PLINK_0.001 530.9 Heartburn Both 427 5551 10 digestive chartreuse4 5551, 427 1388, 103 1388, 119 1387, 100 1388, 105 -0.0061 0.0507 0.904 0.04376 0.994 0.9 1.1 0.152 0.139 0.275 0.5603 1.16 0.886 1.53 -0.0406 0.145 0.78 0.1081 0.96 0.722 1.28 0.00182 0.144 0.99 0.004399 1 0.756 1.33 PRS_PLINK_0.001 531 Peptic ulcer (excl. esophageal) Both 1096 17512 10 digestive chartreuse4 17512, 1096 4378, 281 4378, 266 4378, 280 4378, 269 -0.0195 0.0311 0.53 0.2758 0.981 0.923 1.04 -0.0611 0.0881 0.488 0.3115 0.941 0.792 1.12 -0.013 0.0872 0.881 0.05479 0.987 0.832 1.17 -0.0453 0.0883 0.608 0.2162 0.956 0.804 1.14 PRS_PLINK_0.001 531.1 Hemorrhage from gastrointestinal ulcer Both 89 1505 10 digestive chartreuse4 1505, 89 377, 21 376, 22 376, 25 376, 21 0.034 0.106 0.749 0.1257 1.03 0.84 1.27 0.051 0.306 0.868 0.06169 1.05 0.578 1.92 0.135 0.296 0.649 0.1878 1.14 0.64 2.05 -0.00561 0.313 0.986 0.006252 0.994 0.538 1.84 PRS_PLINK_0.001 531.2 Gastric ulcer Both 636 10031 10 digestive chartreuse4 10031, 636 2508, 158 2508, 151 2507, 165 2508, 162 0.0113 0.0413 0.785 0.1051 1.01 0.933 1.1 -0.0496 0.117 0.671 0.1734 0.952 0.757 1.2 0.0345 0.115 0.764 0.1169 1.04 0.827 1.3 0.0113 0.116 0.922 0.0353 1.01 0.806 1.27 PRS_PLINK_0.001 531.3 Duodenal ulcer Both 450 7322 10 digestive chartreuse4 7322, 450 1831, 122 1830, 116 1830, 110 1831, 102 -0.0848 0.0485 0.0801 1.097 0.919 0.835 1.01 -0.0493 0.133 0.712 0.1478 0.952 0.733 1.24 -0.0868 0.135 0.521 0.2833 0.917 0.703 1.2 -0.145 0.138 0.293 0.5325 0.865 0.66 1.13 PRS_PLINK_0.001 531.4 Peptic ulcer, site unspecified Both 45 978 10 digestive chartreuse4 978, 45 245, 11 244, 9 244, 10 245, 15 0.123 0.147 0.404 0.3934 1.13 0.848 1.51 -0.22 0.44 0.616 0.2102 0.802 0.339 1.9 -0.115 0.418 0.783 0.1062 0.891 0.393 2.02 0.222 0.385 0.563 0.2491 1.25 0.587 2.66 PRS_PLINK_0.001 532 Dysphagia Both 1080 16582 10 digestive chartreuse4 16582, 1080 4145, 299 4145, 264 4145, 262 4146, 255 -0.0504 0.0315 0.109 0.9612 0.951 0.894 1.01 -0.116 0.0872 0.185 0.733 0.891 0.751 1.06 -0.127 0.0874 0.146 0.8344 0.881 0.742 1.05 -0.171 0.0884 0.053 1.276 0.843 0.709 1 PRS_PLINK_0.001 535 Gastritis and duodenitis Both 5208 68217 10 digestive chartreuse4 68217, 5208 17054, 1321 17054, 1283 17054, 1278 17054, 1326 0.000266 0.0144 0.985 0.006447 1 0.972 1.03 -0.0336 0.0407 0.409 0.3883 0.967 0.893 1.05 -0.0377 0.0408 0.355 0.4497 0.963 0.889 1.04 -0.00636 0.0406 0.875 0.05775 0.994 0.918 1.08 PRS_PLINK_0.001 535.1 Acute gastritis Both 220 2947 10 digestive chartreuse4 2947, 220 737, 59 737, 52 736, 55 737, 54 -0.0284 0.0711 0.689 0.1615 0.972 0.845 1.12 -0.113 0.195 0.561 0.2509 0.893 0.609 1.31 -0.0392 0.193 0.839 0.07629 0.962 0.659 1.4 -0.094 0.194 0.627 0.2024 0.91 0.623 1.33 PRS_PLINK_0.001 535.2 Atrophic gastritis Both 62 868 10 digestive chartreuse4 868, 62 217, 15 217, 13 217, 18 217, 16 0.00938 0.126 0.941 0.02654 1.01 0.788 1.29 -0.123 0.374 0.743 0.1292 0.884 0.425 1.84 0.185 0.353 0.599 0.2222 1.2 0.603 2.4 0.0818 0.364 0.822 0.08494 1.09 0.532 2.22 PRS_PLINK_0.001 535.6 Duodenitis Both 1397 19254 10 digestive chartreuse4 19254, 1397 4813, 360 4813, 365 4813, 336 4814, 336 -0.0472 0.0278 0.0892 1.05 0.954 0.903 1.01 0.0104 0.077 0.893 0.04921 1.01 0.869 1.18 -0.0639 0.0787 0.417 0.3803 0.938 0.804 1.09 -0.0714 0.0788 0.365 0.4373 0.931 0.798 1.09 PRS_PLINK_0.001 535.8 Other specified gastritis Both 1504 20373 10 digestive chartreuse4 20373, 1504 5094, 386 5093, 389 5093, 350 5093, 379 -0.0174 0.0267 0.515 0.2881 0.983 0.933 1.04 0.00981 0.0745 0.895 0.04807 1.01 0.873 1.17 -0.105 0.0766 0.171 0.7664 0.901 0.775 1.05 -0.0142 0.0753 0.85 0.0706 0.986 0.851 1.14 PRS_PLINK_0.001 535.9 Gastritis and duodenitis, NOS Both 26 284 10 digestive chartreuse4 284, 26 71, 6 71, 4 71, 7 71, 9 0.214 0.198 0.28 0.5522 1.24 0.84 1.83 -0.317 0.598 0.596 0.225 0.728 0.225 2.35 -0.0802 0.555 0.885 0.05305 0.923 0.311 2.74 0.331 0.517 0.522 0.2825 1.39 0.505 3.84 PRS_PLINK_0.001 536.8 Dyspepsia and other specified disorders of function of stomach Both 42 580 10 digestive chartreuse4 580, 42 145, 11 145, 6 145, 10 145, 15 0.0391 0.164 0.812 0.09059 1.04 0.754 1.43 -0.561 0.477 0.239 0.6215 0.571 0.224 1.45 -0.0646 0.434 0.882 0.05468 0.937 0.4 2.19 0.26 0.408 0.524 0.2808 1.3 0.583 2.88 PRS_PLINK_0.001 537 Other disorders of stomach and duodenum Both 550 8487 10 digestive chartreuse4 8487, 550 2122, 138 2122, 134 2121, 147 2122, 131 -0.0205 0.0445 0.646 0.19 0.98 0.898 1.07 -0.0311 0.125 0.803 0.09539 0.969 0.759 1.24 0.049 0.122 0.688 0.1622 1.05 0.827 1.33 -0.0629 0.126 0.617 0.2096 0.939 0.734 1.2 PRS_PLINK_0.001 540 Appendiceal conditions Both 727 7923 10 digestive chartreuse4 7923, 727 1981, 192 1981, 169 1980, 180 1981, 186 -0.0251 0.0387 0.517 0.2861 0.975 0.904 1.05 -0.123 0.11 0.263 0.5796 0.884 0.713 1.1 -0.0558 0.109 0.607 0.2165 0.946 0.764 1.17 -0.0366 0.108 0.735 0.1335 0.964 0.78 1.19 PRS_PLINK_0.001 540.1 Appendicitis Both 690 7428 10 digestive chartreuse4 7428, 690 1857, 180 1857, 165 1857, 168 1857, 177 -0.0248 0.0399 0.535 0.272 0.976 0.902 1.05 -0.0843 0.112 0.453 0.3435 0.919 0.737 1.15 -0.0648 0.112 0.563 0.2491 0.937 0.752 1.17 -0.0251 0.111 0.821 0.0854 0.975 0.784 1.21 PRS_PLINK_0.001 540.11 Acute appendicitis Both 630 6587 10 digestive chartreuse4 6587, 630 1647, 174 1647, 138 1646, 149 1647, 169 -0.0179 0.0417 0.668 0.1755 0.982 0.905 1.07 -0.23 0.119 0.0532 1.274 0.795 0.629 1 -0.15 0.117 0.2 0.6985 0.861 0.684 1.08 -0.0334 0.114 0.77 0.1136 0.967 0.773 1.21 PRS_PLINK_0.001 550 Abdominal hernia Both 9447 74083 10 digestive chartreuse4 74083, 9447 18520, 2413 18521, 2301 18520, 2327 18521, 2406 -0.00545 0.0111 0.623 0.2056 0.995 0.973 1.02 -0.0454 0.0313 0.147 0.8329 0.956 0.899 1.02 -0.0308 0.0313 0.326 0.4874 0.97 0.912 1.03 0.00148 0.0312 0.962 0.01674 1 0.942 1.06 PRS_PLINK_0.001 550.1 Inguinal hernia Both 3756 32050 10 digestive chartreuse4 32050, 3756 8013, 991 8012, 881 8012, 901 8013, 983 -0.00501 0.0173 0.772 0.1123 0.995 0.962 1.03 -0.124 0.0491 0.0116 1.934 0.883 0.802 0.973 -0.106 0.0489 0.03 1.523 0.899 0.817 0.99 -0.0215 0.0481 0.655 0.1835 0.979 0.891 1.08 PRS_PLINK_0.001 550.2 Diaphragmatic hernia Both 5052 62598 10 digestive chartreuse4 62598, 5052 15649, 1266 15649, 1221 15649, 1260 15650, 1305 -0.00264 0.0147 0.857 0.06677 0.997 0.969 1.03 -0.0353 0.0417 0.397 0.4007 0.965 0.89 1.05 -0.00959 0.0415 0.817 0.0876 0.99 0.913 1.07 0.0242 0.0413 0.558 0.2531 1.02 0.945 1.11 PRS_PLINK_0.001 550.3 Femoral hernia Both 144 1649 10 digestive chartreuse4 1649, 144 413, 43 412, 34 412, 34 412, 33 -0.123 0.0867 0.155 0.8099 0.884 0.746 1.05 -0.264 0.236 0.264 0.5784 0.768 0.483 1.22 -0.184 0.239 0.441 0.3555 0.832 0.521 1.33 -0.228 0.239 0.34 0.4681 0.796 0.498 1.27 PRS_PLINK_0.001 550.4 Umbilical hernia Both 690 9574 10 digestive chartreuse4 9574, 690 2394, 154 2393, 188 2393, 162 2394, 186 0.0351 0.0394 0.373 0.4281 1.04 0.959 1.12 0.193 0.112 0.0861 1.065 1.21 0.973 1.51 0.0528 0.116 0.649 0.1875 1.05 0.84 1.32 0.21 0.113 0.0627 1.202 1.23 0.989 1.54 PRS_PLINK_0.001 550.5 Ventral hernia Both 638 8772 10 digestive chartreuse4 8772, 638 2193, 157 2193, 159 2193, 178 2193, 144 -0.0248 0.0411 0.546 0.263 0.975 0.9 1.06 0.0108 0.116 0.926 0.03347 1.01 0.805 1.27 0.118 0.114 0.301 0.5219 1.12 0.9 1.41 -0.0837 0.12 0.484 0.3151 0.92 0.727 1.16 PRS_PLINK_0.001 555 Inflammatory bowel disease and other gastroenteritis and colitis Both 954 11569 10 digestive chartreuse4 11569, 954 2892, 231 2892, 267 2892, 244 2892, 212 -0.0212 0.0335 0.526 0.2787 0.979 0.917 1.05 0.144 0.0935 0.123 0.9086 1.15 0.962 1.39 0.0591 0.0954 0.536 0.2711 1.06 0.88 1.28 -0.0964 0.0989 0.329 0.4823 0.908 0.748 1.1 PRS_PLINK_0.001 555.1 Regional enteritis Both 343 4509 10 digestive chartreuse4 4509, 343 1128, 94 1127, 98 1127, 77 1127, 74 -0.0905 0.0545 0.0969 1.014 0.913 0.821 1.02 0.0503 0.15 0.736 0.1329 1.05 0.784 1.41 -0.196 0.158 0.215 0.6683 0.822 0.603 1.12 -0.243 0.16 0.129 0.8879 0.784 0.573 1.07 PRS_PLINK_0.001 555.2 Ulcerative colitis Both 702 8197 10 digestive chartreuse4 8197, 702 2049, 162 2049, 198 2049, 184 2049, 158 0.00132 0.0393 0.973 0.01178 1 0.927 1.08 0.199 0.11 0.0706 1.151 1.22 0.983 1.51 0.135 0.112 0.229 0.6401 1.14 0.919 1.43 -0.0426 0.116 0.714 0.1463 0.958 0.763 1.2 PRS_PLINK_0.001 555.21 Ulcerative colitis (chronic) Both 123 1404 10 digestive chartreuse4 1404, 123 351, 25 351, 36 351, 31 351, 31 0.0681 0.0949 0.473 0.3253 1.07 0.889 1.29 0.386 0.269 0.151 0.8208 1.47 0.869 2.49 0.187 0.277 0.499 0.3019 1.21 0.701 2.07 0.166 0.278 0.551 0.2588 1.18 0.684 2.04 PRS_PLINK_0.001 556 Ulceration of the lower GI tract Both 212 2745 10 digestive chartreuse4 2745, 212 687, 51 686, 51 686, 58 686, 52 0.0238 0.0713 0.739 0.1314 1.02 0.891 1.18 -0.0302 0.204 0.882 0.0545 0.97 0.651 1.45 0.128 0.197 0.517 0.2866 1.14 0.772 1.67 0.0253 0.203 0.9 0.04554 1.03 0.69 1.53 PRS_PLINK_0.001 556.1 Ulceration of intestine Both 132 1706 10 digestive chartreuse4 1706, 132 427, 36 426, 36 426, 27 427, 33 -0.066 0.0879 0.453 0.3442 0.936 0.788 1.11 -0.0251 0.244 0.918 0.0372 0.975 0.605 1.57 -0.251 0.259 0.333 0.4773 0.778 0.468 1.29 -0.092 0.247 0.71 0.1489 0.912 0.562 1.48 PRS_PLINK_0.001 557 Intestinal malabsorption (non-celiac) Both 84 806 10 digestive chartreuse4 806, 84 202, 24 201, 15 201, 25 202, 20 -0.0385 0.119 0.745 0.1277 0.962 0.763 1.21 -0.411 0.334 0.219 0.66 0.663 0.345 1.28 0.0781 0.3 0.795 0.09973 1.08 0.6 1.95 -0.12 0.318 0.706 0.151 0.887 0.476 1.65 PRS_PLINK_0.001 557.1 Celiac disease Both 440 4910 10 digestive chartreuse4 4910, 440 1228, 106 1227, 124 1227, 118 1228, 92 -0.085 0.0503 0.0909 1.041 0.918 0.832 1.01 0.167 0.138 0.226 0.646 1.18 0.902 1.55 0.104 0.14 0.458 0.3394 1.11 0.844 1.46 -0.163 0.149 0.272 0.5651 0.849 0.635 1.14 PRS_PLINK_0.001 558 Noninfectious gastroenteritis Both 2884 40649 10 digestive chartreuse4 40649, 2884 10162, 746 10162, 690 10162, 724 10162, 724 -0.0155 0.0193 0.42 0.3765 0.985 0.948 1.02 -0.0718 0.0547 0.189 0.7232 0.931 0.836 1.04 -0.0226 0.0541 0.676 0.1702 0.978 0.879 1.09 -0.029 0.0543 0.593 0.2268 0.971 0.873 1.08 PRS_PLINK_0.001 559 Ileostomy status Both 302 4277 10 digestive chartreuse4 4277, 302 1070, 81 1069, 74 1069, 73 1069, 74 -0.0243 0.0595 0.683 0.1656 0.976 0.869 1.1 -0.0757 0.165 0.647 0.189 0.927 0.671 1.28 -0.091 0.166 0.583 0.2342 0.913 0.66 1.26 -0.0855 0.166 0.607 0.2165 0.918 0.662 1.27 PRS_PLINK_0.001 560 Intestinal obstruction without mention of hernia Both 700 10054 10 digestive chartreuse4 10054, 700 2514, 170 2513, 184 2513, 171 2514, 175 0.00585 0.0393 0.882 0.05472 1.01 0.931 1.09 0.0748 0.11 0.496 0.3045 1.08 0.869 1.34 0.00641 0.112 0.954 0.02034 1.01 0.809 1.25 0.0244 0.111 0.827 0.08266 1.02 0.824 1.27 PRS_PLINK_0.001 560.1 Paralytic ileus Both 84 1267 10 digestive chartreuse4 1267, 84 317, 23 317, 19 316, 20 317, 22 -0.0251 0.111 0.821 0.08539 0.975 0.784 1.21 -0.193 0.312 0.536 0.2706 0.825 0.448 1.52 -0.138 0.307 0.653 0.1848 0.871 0.477 1.59 -0.0563 0.299 0.851 0.07027 0.945 0.526 1.7 PRS_PLINK_0.001 560.2 Impaction of intestine Both 31 664 10 digestive chartreuse4 664, 31 166, 11 166, 8 166, 7 166, 5 -0.418 0.176 0.0172 1.763 0.658 0.467 0.929 -0.292 0.445 0.511 0.2913 0.747 0.312 1.79 -0.453 0.46 0.325 0.4886 0.636 0.258 1.57 -0.779 0.508 0.125 0.9027 0.459 0.169 1.24 PRS_PLINK_0.001 560.3 Peritoneal or intestinal adhesions Both 167 2220 10 digestive chartreuse4 2220, 167 555, 26 555, 53 555, 44 555, 44 0.13 0.0803 0.107 0.9718 1.14 0.973 1.33 0.7 0.243 0.00392 2.406 2.01 1.25 3.24 0.519 0.249 0.0375 1.426 1.68 1.03 2.74 0.526 0.25 0.0356 1.448 1.69 1.04 2.76 PRS_PLINK_0.001 560.4 Other intestinal obstruction Both 621 8653 10 digestive chartreuse4 8653, 621 2164, 145 2163, 169 2163, 151 2163, 156 0.0221 0.0418 0.597 0.2243 1.02 0.942 1.11 0.146 0.117 0.212 0.6727 1.16 0.92 1.45 0.043 0.12 0.719 0.143 1.04 0.826 1.32 0.0739 0.119 0.535 0.2712 1.08 0.852 1.36 PRS_PLINK_0.001 561 Symptoms involving digestive system Both 3382 41675 10 digestive chartreuse4 41675, 3382 10418, 843 10419, 814 10418, 811 10419, 914 0.0201 0.0179 0.262 0.5811 1.02 0.985 1.06 -0.0285 0.0511 0.577 0.2388 0.972 0.879 1.07 -0.0391 0.0512 0.445 0.3518 0.962 0.87 1.06 0.0793 0.0499 0.112 0.9494 1.08 0.982 1.19 PRS_PLINK_0.001 561.1 Diarrhea Both 102 1177 10 digestive chartreuse4 1177, 102 295, 20 294, 19 294, 29 294, 34 0.253 0.102 0.0132 1.881 1.29 1.05 1.57 -0.0192 0.32 0.952 0.02128 0.981 0.524 1.84 0.378 0.295 0.201 0.6973 1.46 0.818 2.6 0.565 0.289 0.0504 1.298 1.76 0.999 3.1 PRS_PLINK_0.001 561.2 Flatulence Both 325 4571 10 digestive chartreuse4 4571, 325 1143, 74 1143, 81 1142, 81 1143, 89 0.0388 0.0578 0.502 0.2995 1.04 0.928 1.16 0.0792 0.165 0.631 0.2002 1.08 0.784 1.5 0.0873 0.165 0.596 0.2247 1.09 0.79 1.51 0.165 0.162 0.308 0.5109 1.18 0.859 1.62 PRS_PLINK_0.001 562 Diverticulosis and diverticulitis Both 5568 56658 10 digestive chartreuse4 56658, 5568 14164, 1302 14164, 1369 14164, 1473 14165, 1424 0.0234 0.0142 0.0981 1.008 1.02 0.996 1.05 0.0479 0.0406 0.238 0.6232 1.05 0.969 1.14 0.112 0.0401 0.00524 2.281 1.12 1.03 1.21 0.0688 0.0404 0.0889 1.051 1.07 0.99 1.16 PRS_PLINK_0.001 562.1 Diverticulosis Both 5561 56640 10 digestive chartreuse4 56640, 5561 14159, 1302 14160, 1367 14160, 1469 14160, 1423 0.0229 0.0142 0.105 0.9768 1.02 0.995 1.05 0.0465 0.0406 0.252 0.5983 1.05 0.967 1.13 0.109 0.0401 0.00639 2.194 1.12 1.03 1.21 0.0682 0.0404 0.0915 1.039 1.07 0.989 1.16 PRS_PLINK_0.001 563 Constipation Both 1615 26715 10 digestive chartreuse4 26715, 1615 6678, 408 6679, 405 6678, 389 6679, 413 0.00389 0.0258 0.88 0.05551 1 0.954 1.06 -0.00406 0.0722 0.955 0.01992 0.996 0.865 1.15 -0.0441 0.0731 0.546 0.2625 0.957 0.829 1.1 0.0181 0.0723 0.802 0.09582 1.02 0.884 1.17 PRS_PLINK_0.001 564 Functional digestive disorders Both 4274 55638 10 digestive chartreuse4 55638, 4274 13909, 1045 13909, 1063 13909, 1075 13910, 1091 0.0112 0.0159 0.482 0.3174 1.01 0.98 1.04 0.0203 0.0452 0.654 0.1845 1.02 0.934 1.12 0.0281 0.0452 0.534 0.2721 1.03 0.941 1.12 0.0331 0.0451 0.464 0.3339 1.03 0.946 1.13 PRS_PLINK_0.001 564.1 Irritable Bowel Syndrome Both 1037 14612 10 digestive chartreuse4 14612, 1037 3652, 263 3653, 259 3653, 249 3653, 266 0.0277 0.0322 0.388 0.4108 1.03 0.965 1.1 -0.00533 0.0905 0.953 0.02089 0.995 0.833 1.19 -0.0356 0.0917 0.698 0.1562 0.965 0.806 1.15 0.0176 0.0903 0.846 0.07273 1.02 0.853 1.21 PRS_PLINK_0.001 564.8 Abnormal findings on exam of gastrointestinal tract/ abdominal area Both 298 4304 10 digestive chartreuse4 4304, 298 1076, 79 1076, 69 1076, 70 1076, 80 0.0115 0.0601 0.849 0.07131 1.01 0.899 1.14 -0.127 0.17 0.453 0.344 0.88 0.631 1.23 -0.111 0.169 0.51 0.2922 0.895 0.642 1.25 0.0181 0.164 0.912 0.03979 1.02 0.738 1.41 PRS_PLINK_0.001 564.9 Personal history of diseases of digestive system Both 3010 39451 10 digestive chartreuse4 39451, 3010 9862, 727 9863, 745 9862, 777 9863, 761 0.00928 0.0189 0.623 0.2052 1.01 0.973 1.05 0.0279 0.0541 0.605 0.2181 1.03 0.925 1.14 0.0656 0.0537 0.221 0.655 1.07 0.961 1.19 0.0347 0.054 0.521 0.2832 1.04 0.931 1.15 PRS_PLINK_0.001 565 Anal and rectal conditions Both 3088 37377 10 digestive chartreuse4 37377, 3088 9345, 749 9344, 775 9344, 769 9344, 795 -0.00383 0.0188 0.839 0.07646 0.996 0.96 1.03 0.0364 0.0533 0.494 0.3059 1.04 0.934 1.15 0.0196 0.0535 0.714 0.1461 1.02 0.918 1.13 0.0584 0.0532 0.273 0.5645 1.06 0.955 1.18 PRS_PLINK_0.001 565.1 Anal and rectal polyp Both 1559 18479 10 digestive chartreuse4 18479, 1559 4620, 386 4620, 390 4619, 379 4620, 404 -0.0104 0.0265 0.695 0.1578 0.99 0.94 1.04 0.0116 0.0747 0.876 0.05728 1.01 0.874 1.17 -0.0189 0.0753 0.802 0.09609 0.981 0.847 1.14 0.0396 0.0745 0.595 0.2256 1.04 0.899 1.2 PRS_PLINK_0.001 567 Peritonitis and retroperitoneal infections Both 116 2307 10 digestive chartreuse4 2307, 116 577, 27 577, 34 576, 24 577, 31 0.0753 0.0946 0.426 0.3704 1.08 0.896 1.3 0.226 0.259 0.382 0.4175 1.25 0.755 2.08 -0.111 0.279 0.691 0.1605 0.895 0.518 1.55 0.0915 0.265 0.73 0.1368 1.1 0.652 1.84 PRS_PLINK_0.001 568 Other disorders of peritoneum Both 604 8269 10 digestive chartreuse4 8269, 604 2068, 156 2067, 167 2067, 144 2067, 137 -0.0427 0.0429 0.319 0.4958 0.958 0.881 1.04 0.0685 0.115 0.552 0.2577 1.07 0.854 1.34 -0.0747 0.12 0.532 0.2739 0.928 0.734 1.17 -0.107 0.121 0.378 0.4222 0.899 0.708 1.14 PRS_PLINK_0.001 568.1 Peritoneal adhesions (postoperative) (postinfection) Both 576 7823 10 digestive chartreuse4 7823, 576 1956, 145 1956, 161 1955, 136 1956, 134 -0.0221 0.0438 0.614 0.2117 0.978 0.898 1.07 0.107 0.118 0.369 0.4333 1.11 0.882 1.4 -0.053 0.123 0.667 0.1757 0.948 0.745 1.21 -0.0629 0.124 0.612 0.2131 0.939 0.736 1.2 PRS_PLINK_0.001 569 Other disorders of intestine Both 735 10611 10 digestive chartreuse4 10611, 735 2652, 188 2653, 195 2652, 173 2653, 179 -0.0237 0.0379 0.532 0.2737 0.977 0.907 1.05 0.0325 0.106 0.758 0.1202 1.03 0.84 1.27 -0.0805 0.109 0.458 0.3389 0.923 0.746 1.14 -0.0584 0.108 0.588 0.2307 0.943 0.764 1.17 PRS_PLINK_0.001 569.1 Toxic gastroenteritis and colitis Both 14 377 10 digestive chartreuse4 377, 14 95, 4 94, 5 94, 4 94, 1 -0.322 0.253 0.204 0.69 0.725 0.441 1.19 0.436 0.62 0.483 0.3164 1.55 0.458 5.21 -0.134 0.663 0.84 0.07595 0.874 0.238 3.21 -1.19 0.838 0.157 0.8048 0.305 0.059 1.58 PRS_PLINK_0.001 569.2 Gastrointestinal complications Both 93 1279 10 digestive chartreuse4 1279, 93 320, 19 320, 27 319, 21 320, 26 0.0244 0.109 0.824 0.08413 1.02 0.827 1.27 0.331 0.301 0.273 0.5643 1.39 0.771 2.51 0.191 0.317 0.547 0.262 1.21 0.65 2.26 0.278 0.304 0.36 0.4432 1.32 0.728 2.4 PRS_PLINK_0.001 571 Chronic liver disease and cirrhosis Both 346 7580 10 digestive chartreuse4 7580, 346 1895, 88 1895, 87 1895, 90 1895, 81 -0.00336 0.0552 0.952 0.02158 0.997 0.894 1.11 -0.011 0.153 0.943 0.02562 0.989 0.732 1.34 0.0119 0.153 0.938 0.02783 1.01 0.75 1.37 -0.0754 0.157 0.63 0.2005 0.927 0.682 1.26 PRS_PLINK_0.001 571.5 Other chronic nonalcoholic liver disease Both 235 4266 10 digestive chartreuse4 4266, 235 1067, 67 1066, 65 1066, 60 1067, 43 -0.104 0.0664 0.118 0.9267 0.901 0.791 1.03 -0.00506 0.178 0.977 0.009983 0.995 0.702 1.41 -0.103 0.182 0.572 0.2428 0.902 0.632 1.29 -0.42 0.198 0.0343 1.464 0.657 0.445 0.969 PRS_PLINK_0.001 571.51 Cirrhosis of liver without mention of alcohol Both 16 270 10 digestive chartreuse4 270, 16 68, 2 67, 5 67, 4 68, 5 0.142 0.227 0.532 0.2738 1.15 0.738 1.8 0.899 0.694 0.195 0.7102 2.46 0.631 9.57 0.903 0.754 0.231 0.6359 2.47 0.563 10.8 0.71 0.718 0.323 0.4907 2.03 0.498 8.31 PRS_PLINK_0.001 571.6 Primary biliary cirrhosis Both 35 625 10 digestive chartreuse4 625, 35 157, 10 156, 9 156, 10 156, 6 -0.0562 0.175 0.748 0.1261 0.945 0.671 1.33 -0.146 0.444 0.743 0.1292 0.864 0.362 2.06 -0.0122 0.432 0.978 0.009881 0.988 0.423 2.31 -0.469 0.486 0.335 0.4753 0.626 0.241 1.62 PRS_PLINK_0.001 571.8 Liver abscess and sequelae of chronic liver disease Both 77 2536 10 digestive chartreuse4 2536, 77 634, 16 634, 14 634, 22 634, 25 0.21 0.119 0.0777 1.109 1.23 0.977 1.56 -0.19 0.352 0.59 0.2293 0.827 0.415 1.65 0.253 0.32 0.428 0.3682 1.29 0.688 2.41 0.412 0.313 0.187 0.7271 1.51 0.818 2.79 PRS_PLINK_0.001 571.81 Portal hypertension Both 32 1353 10 digestive chartreuse4 1353, 32 339, 9 338, 7 338, 7 338, 9 0.0289 0.181 0.873 0.05897 1.03 0.722 1.47 -0.553 0.487 0.256 0.5913 0.575 0.222 1.49 -0.47 0.476 0.323 0.4905 0.625 0.246 1.59 -0.0745 0.448 0.868 0.06154 0.928 0.386 2.23 PRS_PLINK_0.001 572 Ascites (non malignant) Both 109 3834 10 digestive chartreuse4 3834, 109 959, 28 958, 34 958, 20 959, 27 -0.0649 0.0963 0.5 0.3007 0.937 0.776 1.13 0.193 0.252 0.444 0.3526 1.21 0.74 1.99 -0.35 0.286 0.221 0.6556 0.705 0.402 1.23 -0.0612 0.266 0.818 0.08731 0.941 0.558 1.58 PRS_PLINK_0.001 573 Other disorders of liver Both 201 3893 10 digestive chartreuse4 3893, 201 974, 55 973, 47 973, 51 973, 48 -0.018 0.0723 0.804 0.09482 0.982 0.852 1.13 -0.157 0.201 0.435 0.3612 0.855 0.576 1.27 -0.1 0.197 0.611 0.2137 0.905 0.615 1.33 -0.16 0.201 0.427 0.3697 0.852 0.575 1.26 PRS_PLINK_0.001 573.2 Liver replaced by transplant Both 13 215 10 digestive chartreuse4 215, 13 54, 5 54, 1 53, 5 54, 2 -0.214 0.253 0.397 0.4009 0.808 0.492 1.32 -1.04 0.825 0.21 0.6783 0.355 0.0704 1.79 0.222 0.636 0.727 0.1384 1.25 0.359 4.35 -0.899 0.744 0.227 0.6441 0.407 0.0947 1.75 PRS_PLINK_0.001 573.3 Hepatomegaly Both 26 746 10 digestive chartreuse4 746, 26 187, 6 186, 6 186, 2 187, 12 0.152 0.198 0.444 0.3524 1.16 0.789 1.72 0.0517 0.526 0.922 0.0354 1.05 0.376 2.95 -0.841 0.667 0.207 0.6837 0.431 0.117 1.59 0.675 0.467 0.148 0.8295 1.97 0.787 4.91 PRS_PLINK_0.001 573.5 Jaundice (not of newborn) Both 142 2268 10 digestive chartreuse4 2268, 142 567, 31 567, 42 567, 38 567, 31 0.0671 0.0869 0.44 0.3565 1.07 0.902 1.27 0.275 0.24 0.252 0.5994 1.32 0.823 2.11 0.204 0.244 0.402 0.3958 1.23 0.761 1.98 0.0276 0.256 0.914 0.03905 1.03 0.623 1.7 PRS_PLINK_0.001 573.7 Abnormal results of function study of liver Both 554 8740 10 digestive chartreuse4 8740, 554 2185, 130 2185, 139 2185, 132 2185, 153 0.062 0.0439 0.158 0.8004 1.06 0.976 1.16 0.0728 0.125 0.561 0.2513 1.08 0.842 1.37 0.0229 0.127 0.857 0.06713 1.02 0.798 1.31 0.154 0.123 0.211 0.675 1.17 0.916 1.48 PRS_PLINK_0.001 573.9 Abnormal serum enzyme levels Both 27 520 10 digestive chartreuse4 520, 27 130, 7 130, 10 130, 4 130, 6 -0.0428 0.189 0.821 0.08584 0.958 0.662 1.39 0.329 0.475 0.488 0.3115 1.39 0.548 3.52 -0.357 0.566 0.528 0.2772 0.7 0.231 2.12 -0.109 0.517 0.834 0.07898 0.897 0.325 2.47 PRS_PLINK_0.001 574 Cholelithiasis and cholecystitis Both 3097 40002 10 digestive chartreuse4 40002, 3097 10001, 792 10000, 827 10000, 748 10001, 730 -0.0165 0.0188 0.38 0.4197 0.984 0.948 1.02 0.047 0.0517 0.364 0.4393 1.05 0.947 1.16 -0.0505 0.053 0.341 0.4675 0.951 0.857 1.05 -0.0799 0.0534 0.135 0.8694 0.923 0.831 1.03 PRS_PLINK_0.001 574.1 Cholelithiasis Both 2651 34734 10 digestive chartreuse4 34734, 2651 8684, 674 8683, 712 8683, 642 8684, 623 -0.0166 0.0203 0.415 0.3816 0.984 0.945 1.02 0.0597 0.0558 0.285 0.5456 1.06 0.952 1.18 -0.0397 0.0573 0.489 0.3109 0.961 0.859 1.08 -0.0741 0.0579 0.2 0.698 0.929 0.829 1.04 PRS_PLINK_0.001 574.11 Cholelithiasis with acute cholecystitis Both 285 3792 10 digestive chartreuse4 3792, 285 948, 78 948, 73 948, 65 948, 69 -0.0602 0.06 0.315 0.5015 0.942 0.837 1.06 -0.0454 0.168 0.787 0.1038 0.956 0.687 1.33 -0.189 0.173 0.275 0.5607 0.828 0.59 1.16 -0.138 0.171 0.421 0.3757 0.872 0.623 1.22 PRS_PLINK_0.001 574.12 Cholelithiasis with other cholecystitis Both 1081 13841 10 digestive chartreuse4 13841, 1081 3461, 288 3460, 287 3460, 257 3460, 249 -0.0405 0.0318 0.202 0.6942 0.96 0.902 1.02 -0.000281 0.0867 0.997 0.001126 1 0.843 1.18 -0.105 0.0891 0.241 0.6182 0.901 0.756 1.07 -0.151 0.0901 0.0939 1.027 0.86 0.721 1.03 PRS_PLINK_0.001 574.2 Calculus of bile duct Both 494 6526 10 digestive chartreuse4 6526, 494 1632, 114 1631, 136 1631, 123 1632, 121 0.0575 0.0473 0.224 0.6495 1.06 0.965 1.16 0.19 0.131 0.147 0.834 1.21 0.936 1.56 0.0808 0.134 0.547 0.2621 1.08 0.834 1.41 0.0688 0.135 0.61 0.2148 1.07 0.823 1.4 PRS_PLINK_0.001 574.3 Cholecystitis without cholelithiasis Both 533 6918 10 digestive chartreuse4 6918, 533 1730, 148 1729, 141 1729, 128 1730, 116 -0.0969 0.0448 0.0305 1.515 0.908 0.831 0.991 -0.0457 0.122 0.708 0.15 0.955 0.752 1.21 -0.149 0.125 0.233 0.6324 0.861 0.674 1.1 -0.244 0.129 0.0573 1.242 0.783 0.609 1.01 PRS_PLINK_0.001 575 Other biliary tract disease Both 676 9730 10 digestive chartreuse4 9730, 676 2433, 186 2432, 181 2432, 136 2433, 173 -0.0559 0.0398 0.16 0.7949 0.946 0.875 1.02 -0.0266 0.108 0.806 0.09373 0.974 0.788 1.2 -0.305 0.116 0.00866 2.063 0.737 0.587 0.926 -0.0611 0.11 0.578 0.2383 0.941 0.759 1.17 PRS_PLINK_0.001 575.1 Cholangitis Both 66 1193 10 digestive chartreuse4 1193, 66 299, 12 298, 13 298, 15 298, 26 0.314 0.126 0.0124 1.908 1.37 1.07 1.75 0.0483 0.385 0.9 0.04572 1.05 0.494 2.23 0.191 0.375 0.611 0.2141 1.21 0.58 2.53 0.735 0.346 0.0338 1.471 2.08 1.06 4.11 PRS_PLINK_0.001 575.2 Obstruction of bile duct Both 105 1928 10 digestive chartreuse4 1928, 105 482, 27 482, 32 482, 30 482, 16 -0.147 0.0969 0.129 0.8881 0.863 0.714 1.04 0.132 0.263 0.616 0.2105 1.14 0.681 1.91 0.108 0.266 0.684 0.1648 1.11 0.662 1.88 -0.524 0.312 0.0933 1.03 0.592 0.321 1.09 PRS_PLINK_0.001 575.6 Cholesterolosis of gallbladder Both 92 1163 10 digestive chartreuse4 1163, 92 291, 27 291, 25 290, 20 291, 20 -0.0829 0.104 0.424 0.3721 0.92 0.751 1.13 -0.0346 0.285 0.903 0.04416 0.966 0.553 1.69 -0.27 0.299 0.366 0.4365 0.763 0.424 1.37 -0.264 0.299 0.377 0.4232 0.768 0.428 1.38 PRS_PLINK_0.001 575.7 Other disorders of gallbladder Both 290 3570 10 digestive chartreuse4 3570, 290 893, 78 892, 83 892, 59 893, 70 -0.0737 0.0601 0.22 0.6574 0.929 0.826 1.05 0.0704 0.164 0.667 0.1758 1.07 0.779 1.48 -0.265 0.177 0.135 0.8698 0.767 0.542 1.09 -0.099 0.171 0.562 0.25 0.906 0.648 1.27 PRS_PLINK_0.001 575.8 Other disorders of biliary tract Both 160 2644 10 digestive chartreuse4 2644, 160 661, 52 661, 41 661, 32 661, 35 -0.174 0.0824 0.0348 1.458 0.84 0.715 0.988 -0.256 0.213 0.229 0.6393 0.774 0.509 1.18 -0.487 0.228 0.0326 1.486 0.615 0.393 0.961 -0.45 0.225 0.0455 1.342 0.638 0.41 0.991 PRS_PLINK_0.001 575.9 Nonspecific abnormal findings on radiological and other examination of biliary tract Both 42 830 10 digestive chartreuse4 830, 42 208, 10 207, 9 207, 7 208, 16 0.155 0.16 0.331 0.4808 1.17 0.854 1.6 -0.0891 0.436 0.838 0.07666 0.915 0.389 2.15 -0.312 0.464 0.501 0.2998 0.732 0.295 1.82 0.566 0.399 0.156 0.8068 1.76 0.806 3.85 PRS_PLINK_0.001 577 Diseases of pancreas Both 384 6739 10 digestive chartreuse4 6739, 384 1685, 102 1685, 105 1684, 91 1685, 86 -0.0827 0.0518 0.111 0.9559 0.921 0.832 1.02 0.0241 0.142 0.866 0.06262 1.02 0.775 1.35 -0.107 0.148 0.471 0.3274 0.899 0.673 1.2 -0.179 0.151 0.235 0.6286 0.836 0.623 1.12 PRS_PLINK_0.001 577.1 Acute pancreatitis Both 310 5027 10 digestive chartreuse4 5027, 310 1257, 78 1257, 87 1256, 76 1257, 69 -0.0583 0.058 0.314 0.5024 0.943 0.842 1.06 0.107 0.16 0.501 0.2997 1.11 0.814 1.52 0.00361 0.165 0.983 0.007634 1 0.726 1.39 -0.121 0.17 0.477 0.3213 0.886 0.636 1.24 PRS_PLINK_0.001 577.2 Chronic pancreatitis Both 42 1287 10 digestive chartreuse4 1287, 42 322, 12 322, 7 321, 9 322, 14 -0.0188 0.15 0.9 0.04581 0.981 0.732 1.32 -0.459 0.448 0.306 0.5145 0.632 0.263 1.52 -0.297 0.419 0.479 0.3201 0.743 0.327 1.69 0.0237 0.384 0.951 0.02191 1.02 0.483 2.17 PRS_PLINK_0.001 577.3 Cyst and pseudocyst of pancreas Both 45 924 10 digestive chartreuse4 924, 45 231, 15 231, 11 231, 8 231, 11 -0.11 0.144 0.447 0.3499 0.896 0.676 1.19 -0.248 0.39 0.524 0.2809 0.78 0.363 1.67 -0.674 0.422 0.11 0.9571 0.51 0.223 1.17 -0.305 0.393 0.438 0.3589 0.737 0.342 1.59 PRS_PLINK_0.001 578 Gastrointestinal hemorrhage Both 4077 52942 10 digestive chartreuse4 52942, 4077 13235, 1034 13235, 1005 13235, 1039 13236, 999 -0.0138 0.0162 0.397 0.4017 0.986 0.955 1.02 -0.025 0.046 0.587 0.2311 0.975 0.891 1.07 0.0108 0.0457 0.814 0.08945 1.01 0.924 1.11 -0.0278 0.0463 0.548 0.2616 0.973 0.888 1.06 PRS_PLINK_0.001 578.1 Hematemesis Both 193 4914 10 digestive chartreuse4 4914, 193 1229, 43 1228, 47 1228, 50 1229, 53 0.0834 0.074 0.26 0.5855 1.09 0.94 1.26 0.0873 0.211 0.679 0.1679 1.09 0.721 1.65 0.153 0.209 0.463 0.3346 1.17 0.774 1.76 0.221 0.206 0.284 0.5461 1.25 0.832 1.87 PRS_PLINK_0.001 578.2 Blood in stool Both 383 6513 10 digestive chartreuse4 6513, 383 1629, 85 1628, 85 1628, 113 1628, 100 0.101 0.0527 0.0552 1.258 1.11 0.998 1.23 -0.00382 0.156 0.98 0.008558 0.996 0.733 1.35 0.287 0.147 0.052 1.284 1.33 0.998 1.78 0.166 0.152 0.273 0.5632 1.18 0.877 1.59 PRS_PLINK_0.001 578.8 Hemorrhage of rectum and anus Both 2793 33689 10 digestive chartreuse4 33689, 2793 8422, 729 8422, 697 8422, 701 8422, 666 -0.0321 0.0197 0.102 0.9896 0.968 0.932 1.01 -0.039 0.0552 0.48 0.3185 0.962 0.863 1.07 -0.0297 0.0552 0.591 0.2286 0.971 0.871 1.08 -0.0837 0.0561 0.136 0.8678 0.92 0.824 1.03 PRS_PLINK_0.001 578.9 Hemorrhage of gastrointestinal tract Both 988 13585 10 digestive chartreuse4 13585, 988 3396, 230 3396, 264 3396, 239 3396, 255 0.0118 0.033 0.721 0.1423 1.01 0.949 1.08 0.147 0.0933 0.115 0.9396 1.16 0.965 1.39 0.0555 0.0955 0.561 0.2508 1.06 0.877 1.27 0.126 0.0944 0.183 0.7375 1.13 0.942 1.36 PRS_PLINK_0.001 579 Other symptoms involving abdomen and pelvis Both 272 3992 10 digestive chartreuse4 3992, 272 998, 66 998, 75 998, 65 998, 66 0.00745 0.063 0.906 0.04298 1.01 0.891 1.14 0.111 0.174 0.524 0.2804 1.12 0.795 1.57 -0.0257 0.179 0.886 0.05266 0.975 0.686 1.38 -0.005 0.179 0.978 0.009764 0.995 0.7 1.41 PRS_PLINK_0.001 579.2 Splenomegaly Both 52 1099 10 digestive chartreuse4 1099, 52 275, 13 275, 13 274, 16 275, 10 -0.0705 0.139 0.613 0.2129 0.932 0.709 1.22 0.00446 0.385 0.991 0.004033 1 0.472 2.14 0.22 0.376 0.559 0.2529 1.25 0.596 2.6 -0.196 0.405 0.627 0.2025 0.822 0.372 1.82 PRS_PLINK_0.001 579.8 Nonspecific abnormal findings in stool contents Both 384 4333 10 digestive chartreuse4 4333, 384 1084, 91 1083, 88 1083, 91 1083, 114 0.0803 0.0541 0.138 0.8598 1.08 0.975 1.2 -0.0328 0.155 0.832 0.0798 0.968 0.714 1.31 0.0137 0.153 0.929 0.03197 1.01 0.75 1.37 0.226 0.147 0.125 0.9038 1.25 0.939 1.67 PRS_PLINK_0.001 580 Nephritis; nephrosis; renal sclerosis Both 175 3827 11 genitourinary black 3827, 175 957, 53 957, 28 956, 52 957, 42 0.0166 0.077 0.829 0.08135 1.02 0.874 1.18 -0.626 0.233 0.0071 2.149 0.535 0.339 0.843 -0.00348 0.198 0.986 0.006125 0.997 0.676 1.47 -0.221 0.208 0.29 0.5383 0.802 0.533 1.21 PRS_PLINK_0.001 580.1 Glomerulonephritis Both 114 2617 11 genitourinary black 2617, 114 655, 36 654, 19 654, 35 654, 24 -0.0516 0.0951 0.588 0.2308 0.95 0.788 1.14 -0.602 0.281 0.0318 1.498 0.547 0.316 0.949 0.0311 0.241 0.897 0.04702 1.03 0.643 1.65 -0.401 0.263 0.128 0.8944 0.669 0.4 1.12 PRS_PLINK_0.001 580.11 Proliferative glomerulonephritis Both 11 191 11 genitourinary black 191, 11 48, 2 48, 2 47, 2 48, 5 0.229 0.296 0.438 0.3587 1.26 0.705 2.25 -0.232 0.9 0.797 0.09875 0.793 0.136 4.63 1.51 0.92 0.101 0.9937 4.51 0.744 27.3 PRS_PLINK_0.001 580.12 Non-proliferative glomerulonephritis Both 23 338 11 genitourinary black 338, 23 85, 7 84, 2 84, 9 85, 5 -0.101 0.212 0.633 0.1987 0.904 0.596 1.37 -1.32 0.695 0.0571 1.243 0.266 0.0682 1.04 0.0528 0.505 0.917 0.03773 1.05 0.392 2.84 -0.41 0.563 0.467 0.3311 0.664 0.22 2 PRS_PLINK_0.001 580.14 Chronic glomerulonephritis, NOS Both 86 2178 11 genitourinary black 2178, 86 545, 29 544, 16 544, 22 545, 19 -0.057 0.108 0.596 0.2245 0.945 0.765 1.17 -0.521 0.307 0.0894 1.049 0.594 0.325 1.08 -0.16 0.284 0.572 0.2427 0.852 0.489 1.49 -0.373 0.292 0.202 0.6937 0.689 0.388 1.22 PRS_PLINK_0.001 580.2 Nephrotic syndrome without mention of glomerulonephritis Both 51 1164 11 genitourinary black 1164, 51 291, 15 291, 7 291, 13 291, 16 0.106 0.14 0.447 0.3495 1.11 0.846 1.46 -0.845 0.433 0.0506 1.295 0.429 0.184 1 -0.171 0.369 0.644 0.1911 0.843 0.409 1.74 0.0585 0.353 0.868 0.0613 1.06 0.531 2.12 PRS_PLINK_0.001 580.3 Nephritis and nephropathy without mention of glomerulonephritis Both 37 634 11 genitourinary black 634, 37 159, 10 158, 7 158, 12 159, 8 0.0181 0.159 0.91 0.04116 1.02 0.745 1.39 -0.334 0.464 0.472 0.3262 0.716 0.289 1.78 0.19 0.42 0.651 0.1866 1.21 0.531 2.75 -0.193 0.45 0.668 0.1752 0.824 0.341 1.99 PRS_PLINK_0.001 580.32 Nephritis and nephropathy with pathological lesion Both 38 650 11 genitourinary black 650, 38 163, 10 162, 6 162, 13 163, 9 0.0582 0.157 0.71 0.1488 1.06 0.78 1.44 -0.486 0.48 0.312 0.5062 0.615 0.24 1.58 0.226 0.413 0.585 0.2332 1.25 0.558 2.81 -0.0972 0.438 0.825 0.08378 0.907 0.384 2.14 PRS_PLINK_0.001 585 Renal failure Both 684 17264 11 genitourinary black 17264, 684 4315, 194 4316, 176 4316, 168 4316, 146 -0.132 0.0388 0.000689 3.162 0.877 0.812 0.946 -0.0967 0.106 0.361 0.4424 0.908 0.738 1.12 -0.136 0.107 0.206 0.6859 0.873 0.708 1.08 -0.265 0.112 0.0175 1.756 0.767 0.616 0.955 PRS_PLINK_0.001 585.1 Acute renal failure Both 341 11278 11 genitourinary black 11278, 341 2819, 91 2819, 90 2819, 85 2820, 75 -0.0679 0.0547 0.215 0.6685 0.934 0.839 1.04 -0.0189 0.15 0.9 0.04596 0.981 0.732 1.32 -0.0623 0.152 0.681 0.1666 0.94 0.698 1.27 -0.176 0.157 0.264 0.5792 0.839 0.617 1.14 PRS_PLINK_0.001 585.2 Renal failure NOS Both 157 3627 11 genitourinary black 3627, 157 907, 43 907, 34 906, 45 907, 35 -0.132 0.0803 0.1 1 0.876 0.749 1.03 -0.213 0.23 0.353 0.4519 0.808 0.515 1.27 0.0514 0.215 0.811 0.09112 1.05 0.691 1.6 -0.177 0.23 0.441 0.3553 0.838 0.534 1.31 PRS_PLINK_0.001 585.3 Chronic renal failure [CKD] Both 290 6513 11 genitourinary black 6513, 290 1629, 88 1628, 68 1628, 69 1628, 65 -0.132 0.0596 0.0273 1.563 0.877 0.78 0.985 -0.245 0.164 0.134 0.8741 0.782 0.568 1.08 -0.235 0.163 0.15 0.8231 0.791 0.574 1.09 -0.289 0.166 0.0824 1.084 0.749 0.541 1.04 PRS_PLINK_0.001 585.31 Renal dialysis Both 65 1270 11 genitourinary black 1270, 65 318, 22 317, 8 317, 19 318, 16 -0.0612 0.121 0.612 0.213 0.941 0.742 1.19 -0.963 0.396 0.0151 1.821 0.382 0.176 0.83 -0.152 0.313 0.627 0.2027 0.859 0.465 1.59 -0.231 0.329 0.483 0.3161 0.794 0.417 1.51 PRS_PLINK_0.001 586 Other disorders of the kidney and ureters Both 523 8522 11 genitourinary black 8522, 523 2131, 127 2130, 131 2130, 138 2131, 127 -0.0177 0.0448 0.693 0.1594 0.982 0.9 1.07 0.0378 0.128 0.767 0.1151 1.04 0.809 1.33 0.0798 0.126 0.527 0.2779 1.08 0.846 1.39 -0.00481 0.129 0.97 0.01313 0.995 0.773 1.28 PRS_PLINK_0.001 586.1 Anatomical abnormatilies of kidney and ureters Both 30 531 11 genitourinary black 531, 30 133, 6 133, 7 132, 7 133, 10 0.0187 0.176 0.915 0.03842 1.02 0.722 1.44 0.35 0.546 0.522 0.282 1.42 0.486 4.14 0.108 0.517 0.835 0.0785 1.11 0.404 3.07 0.42 0.488 0.39 0.4088 1.52 0.584 3.96 PRS_PLINK_0.001 586.11 Small kidney Both 26 448 11 genitourinary black 448, 26 112, 4 112, 9 112, 4 112, 9 0.0458 0.193 0.813 0.09003 1.05 0.717 1.53 0.876 0.579 0.13 0.8851 2.4 0.772 7.46 -0.146 0.607 0.81 0.09168 0.864 0.263 2.84 0.616 0.548 0.261 0.583 1.85 0.632 5.42 PRS_PLINK_0.001 586.2 Cyst of kidney, acquired Both 192 3139 11 genitourinary black 3139, 192 785, 52 785, 44 784, 56 785, 40 -0.048 0.0738 0.515 0.288 0.953 0.825 1.1 -0.164 0.207 0.429 0.3675 0.849 0.565 1.27 0.0635 0.196 0.746 0.127 1.07 0.725 1.57 -0.267 0.214 0.212 0.6746 0.766 0.504 1.16 PRS_PLINK_0.001 586.3 Vascular disorders of kidney/hypertrophy Both 6 192 11 genitourinary black 192, 6 48, 1 48, 2 48, 1 48, 2 -0.168 0.357 0.637 0.1956 0.845 0.42 1.7 0.446 0.99 0.653 0.1854 1.56 0.224 10.9 -0.287 0.951 0.763 0.1175 0.751 0.116 4.84 0.664 0.899 0.461 0.3367 1.94 0.333 11.3 PRS_PLINK_0.001 586.4 Stricture/obstruction of ureter Both 150 2365 11 genitourinary black 2365, 150 592, 32 591, 33 591, 49 591, 36 0.0376 0.0846 0.656 0.1829 1.04 0.88 1.23 0.0535 0.249 0.83 0.08092 1.05 0.647 1.72 0.438 0.231 0.0581 1.236 1.55 0.985 2.44 0.0958 0.246 0.697 0.1567 1.1 0.679 1.78 PRS_PLINK_0.001 587 Kidney replaced by transpant Both 63 940 11 genitourinary black 940, 63 235, 14 235, 8 235, 24 235, 17 0.124 0.127 0.327 0.4851 1.13 0.883 1.45 -0.406 0.435 0.351 0.4548 0.667 0.284 1.56 0.599 0.342 0.0802 1.096 1.82 0.93 3.56 0.266 0.366 0.468 0.3298 1.3 0.636 2.67 PRS_PLINK_0.001 588 Disorders resulting from impaired renal function Both 17 254 11 genitourinary black 254, 17 64, 4 63, 4 63, 6 64, 3 0.0413 0.225 0.855 0.06821 1.04 0.67 1.62 0.0896 0.651 0.891 0.05033 1.09 0.305 3.92 0.152 0.615 0.805 0.09439 1.16 0.349 3.89 -0.319 0.667 0.632 0.1992 0.727 0.196 2.69 PRS_PLINK_0.001 589 Abnormal results of function study of kidney Both 17 293 11 genitourinary black 293, 17 74, 4 73, 3 73, 5 73, 5 0.262 0.268 0.33 0.4817 1.3 0.768 2.2 0.0541 0.752 0.943 0.02568 1.06 0.242 4.61 0.474 0.652 0.467 0.3303 1.61 0.447 5.77 0.43 0.688 0.532 0.2743 1.54 0.399 5.92 PRS_PLINK_0.001 590 Pyelonephritis Both 222 3463 11 genitourinary black 3463, 222 866, 52 866, 63 865, 50 866, 57 -0.00921 0.069 0.894 0.04874 0.991 0.865 1.13 0.21 0.192 0.273 0.5634 1.23 0.847 1.8 -0.0355 0.201 0.86 0.06546 0.965 0.65 1.43 0.131 0.196 0.503 0.2985 1.14 0.776 1.68 PRS_PLINK_0.001 591 Urinary tract infection Both 2008 31358 11 genitourinary black 31358, 2008 7839, 484 7839, 490 7839, 526 7840, 508 0.00434 0.0231 0.851 0.07006 1 0.96 1.05 0.022 0.066 0.739 0.1314 1.02 0.898 1.16 0.0898 0.0651 0.168 0.775 1.09 0.963 1.24 0.065 0.0658 0.323 0.4904 1.07 0.938 1.21 PRS_PLINK_0.001 592 Cystitis and urethritis Both 534 7343 11 genitourinary black 7343, 534 1836, 134 1836, 117 1835, 134 1836, 149 0.0452 0.0448 0.313 0.5045 1.05 0.958 1.14 -0.127 0.13 0.329 0.4832 0.881 0.682 1.14 -0.0125 0.126 0.921 0.03566 0.988 0.771 1.27 0.114 0.124 0.354 0.4508 1.12 0.88 1.43 PRS_PLINK_0.001 592.1 Cystitis Both 530 7173 11 genitourinary black 7173, 530 1794, 132 1793, 115 1793, 136 1793, 147 0.0434 0.045 0.335 0.4755 1.04 0.956 1.14 -0.131 0.131 0.319 0.4968 0.877 0.679 1.13 0.021 0.126 0.868 0.06131 1.02 0.797 1.31 0.116 0.125 0.352 0.4533 1.12 0.88 1.43 PRS_PLINK_0.001 592.11 Acute cystitis Both 24 353 11 genitourinary black 353, 24 89, 6 88, 7 88, 4 88, 7 0.158 0.207 0.446 0.3504 1.17 0.78 1.76 0.322 0.543 0.553 0.2569 1.38 0.476 4 -0.491 0.603 0.415 0.3822 0.612 0.188 1.99 0.291 0.529 0.583 0.2345 1.34 0.474 3.77 PRS_PLINK_0.001 592.12 Chronic cystitis Both 154 2221 11 genitourinary black 2221, 154 556, 34 555, 42 555, 33 555, 45 0.0839 0.0822 0.307 0.5122 1.09 0.926 1.28 0.21 0.235 0.372 0.4297 1.23 0.778 1.96 -0.0311 0.247 0.9 0.04575 0.969 0.597 1.57 0.287 0.233 0.218 0.6622 1.33 0.844 2.1 PRS_PLINK_0.001 592.13 Chronic interstitial cystitis Both 53 576 11 genitourinary black 576, 53 144, 8 144, 11 144, 12 144, 22 0.223 0.141 0.114 0.9426 1.25 0.948 1.65 0.384 0.451 0.395 0.4037 1.47 0.607 3.55 0.391 0.451 0.386 0.4138 1.48 0.611 3.58 0.975 0.412 0.0179 1.747 2.65 1.18 5.94 PRS_PLINK_0.001 592.2 Urethritis and urethral syndrome Both 25 449 11 genitourinary black 449, 25 113, 7 112, 2 112, 10 112, 6 0.109 0.197 0.579 0.2375 1.12 0.758 1.64 -1.18 0.665 0.0767 1.115 0.308 0.0836 1.13 0.303 0.482 0.53 0.2757 1.35 0.526 3.48 -0.077 0.529 0.884 0.05347 0.926 0.328 2.61 PRS_PLINK_0.001 593 Hematuria Both 3413 40838 11 genitourinary black 40838, 3413 10210, 832 10209, 848 10209, 865 10210, 868 0.00538 0.0179 0.763 0.1172 1.01 0.971 1.04 0.0198 0.0508 0.697 0.1567 1.02 0.923 1.13 0.036 0.0507 0.477 0.3212 1.04 0.939 1.14 0.0449 0.0508 0.376 0.4244 1.05 0.947 1.16 PRS_PLINK_0.001 594 Urinary calculus Both 1328 16182 11 genitourinary black 16182, 1328 4046, 322 4045, 344 4045, 335 4046, 327 -0.00383 0.0286 0.893 0.04891 0.996 0.942 1.05 0.0694 0.0806 0.389 0.4103 1.07 0.915 1.26 0.0464 0.0812 0.568 0.246 1.05 0.893 1.23 0.0128 0.082 0.876 0.05769 1.01 0.863 1.19 PRS_PLINK_0.001 594.1 Calculus of kidney Both 630 8051 11 genitourinary black 8051, 630 2013, 147 2013, 170 2012, 166 2013, 147 -7.51e-05 0.0412 0.999 0.0006318 1 0.922 1.08 0.145 0.116 0.213 0.6712 1.16 0.92 1.45 0.122 0.117 0.297 0.5271 1.13 0.898 1.42 -0.0271 0.121 0.823 0.08473 0.973 0.768 1.23 PRS_PLINK_0.001 594.2 Calculus of lower urinary tract Both 152 1900 11 genitourinary black 1900, 152 475, 35 475, 32 475, 47 475, 38 0.00733 0.0849 0.931 0.03099 1.01 0.853 1.19 -0.13 0.249 0.601 0.2212 0.878 0.538 1.43 0.297 0.23 0.196 0.7068 1.35 0.857 2.11 0.0498 0.241 0.836 0.07782 1.05 0.656 1.68 PRS_PLINK_0.001 594.3 Calculus of ureter Both 502 6024 11 genitourinary black 6024, 502 1506, 135 1506, 127 1506, 132 1506, 108 -0.0885 0.0463 0.0558 1.253 0.915 0.836 1 -0.0647 0.128 0.614 0.2117 0.937 0.729 1.21 -0.0269 0.127 0.832 0.07968 0.973 0.759 1.25 -0.24 0.134 0.0735 1.134 0.786 0.605 1.02 PRS_PLINK_0.001 594.8 Renal colic Both 426 5162 11 genitourinary black 5162, 426 1291, 105 1290, 109 1290, 100 1291, 112 0.0339 0.0508 0.505 0.2971 1.03 0.936 1.14 0.0442 0.142 0.755 0.122 1.05 0.792 1.38 -0.0292 0.145 0.84 0.0757 0.971 0.731 1.29 0.0778 0.141 0.581 0.2355 1.08 0.82 1.43 PRS_PLINK_0.001 595 Hydronephrosis Both 277 4943 11 genitourinary black 4943, 277 1236, 59 1236, 78 1235, 73 1236, 67 0.0205 0.0622 0.742 0.1298 1.02 0.904 1.15 0.299 0.176 0.0886 1.053 1.35 0.956 1.9 0.239 0.178 0.18 0.7454 1.27 0.896 1.8 0.168 0.182 0.354 0.4506 1.18 0.829 1.69 PRS_PLINK_0.001 596 Other disorders of bladder Both 1938 24536 11 genitourinary black 24536, 1938 6134, 520 6134, 484 6134, 467 6134, 467 -0.0469 0.0236 0.0466 1.331 0.954 0.911 0.999 -0.069 0.0656 0.293 0.5328 0.933 0.821 1.06 -0.103 0.0663 0.122 0.9135 0.903 0.793 1.03 -0.107 0.0666 0.107 0.9702 0.898 0.788 1.02 PRS_PLINK_0.001 596.1 Bladder neck obstruction Both 411 4916 11 genitourinary black 4916, 411 1229, 113 1229, 102 1229, 97 1229, 99 -0.0435 0.0518 0.401 0.3968 0.957 0.865 1.06 -0.102 0.142 0.471 0.3267 0.903 0.684 1.19 -0.156 0.144 0.276 0.5594 0.855 0.646 1.13 -0.12 0.144 0.402 0.3959 0.887 0.669 1.17 PRS_PLINK_0.001 596.5 Functional disorders of bladder Both 270 4289 11 genitourinary black 4289, 270 1073, 72 1072, 69 1072, 59 1072, 70 -0.0804 0.0639 0.208 0.6815 0.923 0.814 1.05 -0.0291 0.173 0.866 0.06254 0.971 0.693 1.36 -0.178 0.18 0.323 0.4906 0.837 0.589 1.19 -0.00361 0.174 0.983 0.007262 0.996 0.709 1.4 PRS_PLINK_0.001 597 Other disorders of urethra and urinary tract Both 787 9812 11 genitourinary black 9812, 787 2452, 188 2453, 216 2453, 189 2453, 194 -0.0171 0.037 0.643 0.1918 0.983 0.914 1.06 0.144 0.104 0.165 0.7835 1.15 0.943 1.41 0.00832 0.107 0.938 0.02783 1.01 0.818 1.24 0.0262 0.107 0.806 0.09372 1.03 0.833 1.26 PRS_PLINK_0.001 597.1 Urethral stricture (not specified as infectious) Both 662 8295 11 genitourinary black 8295, 662 2074, 150 2074, 178 2073, 165 2074, 169 0.0218 0.0403 0.589 0.2299 1.02 0.944 1.11 0.181 0.115 0.115 0.9393 1.2 0.957 1.5 0.1 0.117 0.392 0.4069 1.11 0.879 1.39 0.108 0.117 0.355 0.4502 1.11 0.886 1.4 PRS_PLINK_0.001 597.2 Urinary complications NEC Both 6 217 11 genitourinary black 217, 6 55, 2 54, 1 54, 1 54, 2 -0.206 0.332 0.535 0.2715 0.814 0.424 1.56 -0.662 0.884 0.454 0.3426 0.516 0.0912 2.92 -0.911 0.883 0.302 0.5198 0.402 0.0713 2.27 -0.108 0.787 0.891 0.05026 0.898 0.192 4.2 PRS_PLINK_0.001 598 Abnormal findings on examination of urine Both 711 8899 11 genitourinary black 8899, 711 2225, 190 2225, 171 2224, 172 2225, 178 -0.0346 0.0387 0.371 0.4305 0.966 0.895 1.04 -0.102 0.109 0.348 0.4586 0.903 0.729 1.12 -0.101 0.109 0.357 0.4473 0.904 0.73 1.12 -0.0761 0.109 0.484 0.3154 0.927 0.749 1.15 PRS_PLINK_0.001 598.9 Other nonspecific findings on examination of urine Both 46 723 11 genitourinary black 723, 46 181, 14 181, 7 180, 10 181, 15 0.0233 0.151 0.877 0.05682 1.02 0.761 1.38 -0.726 0.454 0.11 0.9604 0.484 0.199 1.18 -0.334 0.412 0.417 0.3797 0.716 0.32 1.6 0.143 0.374 0.703 0.1531 1.15 0.554 2.4 PRS_PLINK_0.001 599 Other symptoms/disorders or the urinary system Both 3516 47518 11 genitourinary black 47518, 3516 11880, 945 11879, 864 11879, 876 11880, 831 -0.0468 0.0176 0.00776 2.11 0.954 0.922 0.988 -0.0853 0.0488 0.0805 1.094 0.918 0.834 1.01 -0.0724 0.0488 0.138 0.8613 0.93 0.845 1.02 -0.126 0.0495 0.0111 1.953 0.882 0.8 0.972 PRS_PLINK_0.001 599.1 Urinary obstruction Both 33 397 11 genitourinary black 397, 33 100, 11 99, 8 99, 7 99, 7 -0.17 0.167 0.309 0.5103 0.843 0.607 1.17 -0.28 0.458 0.541 0.2668 0.756 0.308 1.85 -0.391 0.477 0.413 0.3844 0.677 0.266 1.72 -0.241 0.494 0.626 0.2033 0.786 0.299 2.07 PRS_PLINK_0.001 599.2 Retention of urine Both 1192 17032 11 genitourinary black 17032, 1192 4258, 316 4258, 309 4258, 307 4258, 260 -0.0653 0.03 0.0295 1.53 0.937 0.883 0.994 -0.0232 0.0828 0.779 0.1083 0.977 0.831 1.15 -0.0244 0.083 0.769 0.114 0.976 0.829 1.15 -0.184 0.0866 0.0335 1.475 0.832 0.702 0.986 PRS_PLINK_0.001 599.3 Dysuria Both 224 3072 11 genitourinary black 3072, 224 768, 51 768, 69 768, 57 768, 47 -0.0216 0.0688 0.753 0.1231 0.979 0.855 1.12 0.302 0.19 0.112 0.9513 1.35 0.932 1.96 0.0999 0.198 0.613 0.2123 1.11 0.75 1.63 -0.0833 0.207 0.687 0.1629 0.92 0.613 1.38 PRS_PLINK_0.001 599.4 Urinary incontinence Both 1617 22789 11 genitourinary black 22789, 1617 5698, 421 5697, 405 5697, 402 5697, 389 -0.0254 0.0259 0.327 0.485 0.975 0.927 1.03 -0.0374 0.072 0.603 0.2197 0.963 0.836 1.11 -0.0364 0.0722 0.615 0.2115 0.964 0.837 1.11 -0.0672 0.073 0.357 0.447 0.935 0.81 1.08 PRS_PLINK_0.001 599.5 Frequency of urination and polyuria Both 762 10271 11 genitourinary black 10271, 762 2568, 204 2568, 173 2567, 175 2568, 210 -0.0115 0.0379 0.761 0.1187 0.989 0.918 1.06 -0.156 0.107 0.143 0.8432 0.855 0.694 1.05 -0.148 0.107 0.166 0.78 0.863 0.7 1.06 0.0441 0.103 0.667 0.1759 1.05 0.855 1.28 PRS_PLINK_0.001 599.6 Oliguria and anuria Both 14 263 11 genitourinary black 263, 14 66, 2 66, 4 65, 3 66, 5 0.172 0.246 0.484 0.3156 1.19 0.734 1.92 0.556 0.759 0.464 0.3333 1.74 0.394 7.72 0.0979 0.766 0.898 0.04655 1.1 0.246 4.95 0.317 0.739 0.668 0.1751 1.37 0.323 5.84 PRS_PLINK_0.001 599.8 Other symptoms involving urinary system Both 15 156 11 genitourinary black 156, 15 39, 4 39, 2 39, 4 39, 5 0.226 0.275 0.411 0.3863 1.25 0.732 2.15 0.303 1.02 0.767 0.1154 1.35 0.183 10 0.0491 0.71 0.945 0.02462 1.05 0.261 4.22 0.849 0.778 0.275 0.5603 2.34 0.509 10.7 PRS_PLINK_0.001 599.9 Other abnormality of urination Both 351 4802 11 genitourinary black 4802, 351 1201, 112 1200, 98 1200, 74 1201, 67 -0.229 0.0546 2.74e-05 4.562 0.795 0.715 0.885 -0.129 0.143 0.368 0.4344 0.879 0.663 1.16 -0.425 0.154 0.00599 2.223 0.654 0.483 0.885 -0.52 0.159 0.00107 2.972 0.594 0.435 0.812 PRS_PLINK_0.001 600 Hyperplasia of prostate Male 2428 22746 11 genitourinary black 22746, 2428 5687, 590 5686, 631 5686, 607 5687, 600 -0.00479 0.0214 0.823 0.08454 0.995 0.954 1.04 0.0591 0.0604 0.328 0.484 1.06 0.942 1.19 0.0199 0.061 0.745 0.1281 1.02 0.905 1.15 -0.00711 0.0614 0.908 0.042 0.993 0.88 1.12 PRS_PLINK_0.001 601 Inflammatory diseases of prostate Male 444 5263 11 genitourinary black 5263, 444 1316, 128 1316, 119 1315, 105 1316, 92 -0.137 0.0497 0.00574 2.241 0.872 0.791 0.961 -0.0683 0.133 0.607 0.2171 0.934 0.72 1.21 -0.193 0.137 0.159 0.7975 0.825 0.631 1.08 -0.34 0.142 0.0166 1.78 0.712 0.539 0.94 PRS_PLINK_0.001 601.1 Prostatitis Male 355 4038 11 genitourinary black 4038, 355 1010, 101 1009, 88 1009, 92 1010, 74 -0.132 0.0562 0.019 1.721 0.877 0.785 0.979 -0.131 0.152 0.388 0.4115 0.877 0.652 1.18 -0.0913 0.15 0.544 0.2647 0.913 0.68 1.23 -0.331 0.159 0.0371 1.431 0.718 0.526 0.98 PRS_PLINK_0.001 601.11 Acute prostatitis Male 51 627 11 genitourinary black 627, 51 157, 24 157, 9 156, 13 157, 5 -0.426 0.145 0.0032 2.494 0.653 0.492 0.867 -1.01 0.396 0.0105 1.979 0.363 0.167 0.789 -0.615 0.355 0.0829 1.082 0.54 0.27 1.08 -1.45 0.469 0.00194 2.712 0.234 0.0933 0.586 PRS_PLINK_0.001 601.12 Chronic prostatitis Male 206 2341 11 genitourinary black 2341, 206 586, 55 585, 52 585, 58 585, 41 -0.0835 0.0732 0.254 0.5956 0.92 0.797 1.06 -0.0369 0.2 0.854 0.06853 0.964 0.651 1.43 0.0631 0.196 0.747 0.1266 1.07 0.726 1.56 -0.303 0.212 0.154 0.8133 0.739 0.487 1.12 PRS_PLINK_0.001 601.3 Orchitis and epididymitis Male 9 133 11 genitourinary black 133, 9 34, 3 33, 1 33, 2 33, 3 -0.0644 0.309 0.835 0.07848 0.938 0.512 1.72 -0.753 0.874 0.389 0.4101 0.471 0.0849 2.61 -0.843 0.969 0.385 0.415 0.431 0.0644 2.88 -0.051 0.765 0.947 0.02371 0.95 0.212 4.26 PRS_PLINK_0.001 601.4 Balanoposthitis Male 47 658 11 genitourinary black 658, 47 165, 14 164, 16 164, 9 165, 8 -0.213 0.143 0.135 0.8698 0.808 0.611 1.07 0.133 0.373 0.721 0.142 1.14 0.55 2.37 -0.341 0.423 0.42 0.3764 0.711 0.311 1.63 -0.431 0.441 0.329 0.4829 0.65 0.274 1.54 PRS_PLINK_0.001 601.8 Other inflammatory disorders of male genital organs Male 50 740 11 genitourinary black 740, 50 185, 11 185, 18 185, 8 185, 13 0.0643 0.14 0.645 0.1904 1.07 0.811 1.4 0.438 0.382 0.252 0.5986 1.55 0.733 3.27 -0.214 0.446 0.632 0.1992 0.808 0.337 1.94 0.261 0.404 0.519 0.2851 1.3 0.588 2.87 PRS_PLINK_0.001 602 Other disorders of prostate Male 300 3301 11 genitourinary black 3301, 300 826, 78 825, 81 825, 85 825, 56 -0.0773 0.0597 0.196 0.7084 0.926 0.823 1.04 0.0331 0.165 0.841 0.07531 1.03 0.748 1.43 0.0941 0.163 0.565 0.248 1.1 0.797 1.51 -0.309 0.181 0.0888 1.052 0.734 0.515 1.05 PRS_PLINK_0.001 603 Other disorders of testis Male 407 5394 11 genitourinary black 5394, 407 1349, 120 1348, 96 1348, 88 1349, 103 -0.0913 0.051 0.0732 1.135 0.913 0.826 1.01 -0.219 0.142 0.122 0.9129 0.803 0.609 1.06 -0.317 0.145 0.0286 1.544 0.728 0.548 0.967 -0.141 0.139 0.313 0.5051 0.869 0.661 1.14 PRS_PLINK_0.001 603.1 Hydrocele Male 272 3332 11 genitourinary black 3332, 272 833, 81 833, 67 833, 53 833, 71 -0.093 0.0623 0.135 0.8685 0.911 0.806 1.03 -0.191 0.171 0.264 0.5785 0.826 0.591 1.16 -0.453 0.182 0.0129 1.889 0.635 0.444 0.908 -0.116 0.169 0.491 0.3089 0.89 0.64 1.24 PRS_PLINK_0.001 604 Disorders of penis Male 617 8267 11 genitourinary black 8267, 617 2067, 162 2067, 170 2066, 135 2067, 150 -0.0387 0.0417 0.354 0.4513 0.962 0.887 1.04 0.0524 0.114 0.645 0.1902 1.05 0.843 1.32 -0.169 0.12 0.16 0.797 0.844 0.667 1.07 -0.0779 0.118 0.508 0.2945 0.925 0.735 1.16 PRS_PLINK_0.001 604.1 Redundant prepuce and phimosis/BXO Male 517 6883 11 genitourinary black 6883, 517 1721, 140 1721, 136 1720, 117 1721, 124 -0.0524 0.0455 0.249 0.604 0.949 0.868 1.04 -0.0213 0.125 0.865 0.06312 0.979 0.766 1.25 -0.162 0.13 0.211 0.6758 0.85 0.66 1.1 -0.125 0.128 0.327 0.4853 0.882 0.687 1.13 PRS_PLINK_0.001 605 Erectile dysfunction [ED] Male 48 689 11 genitourinary black 689, 48 173, 11 172, 13 172, 9 172, 15 0.0469 0.148 0.751 0.1243 1.05 0.784 1.4 0.175 0.413 0.672 0.1723 1.19 0.53 2.67 -0.259 0.439 0.555 0.2557 0.772 0.327 1.82 0.332 0.397 0.403 0.3952 1.39 0.64 3.03 PRS_PLINK_0.001 608 Other disorders of male genital organs Male 567 7076 11 genitourinary black 7076, 567 1769, 139 1769, 150 1769, 128 1769, 150 -0.0232 0.0439 0.598 0.2234 0.977 0.896 1.06 0.0818 0.122 0.503 0.2987 1.09 0.854 1.38 -0.0715 0.127 0.573 0.2416 0.931 0.726 1.19 0.091 0.123 0.458 0.3393 1.1 0.861 1.39 PRS_PLINK_0.001 609 Male infertility and abnormal spermatozoa Male 54 490 11 genitourinary black 490, 54 123, 9 122, 14 122, 16 123, 15 0.089 0.145 0.538 0.2689 1.09 0.823 1.45 0.514 0.43 0.232 0.635 1.67 0.72 3.88 0.559 0.416 0.179 0.7474 1.75 0.774 3.95 0.504 0.42 0.23 0.6382 1.65 0.727 3.77 PRS_PLINK_0.001 609.1 Infertility, male Male 8 150 11 genitourinary black 150, 8 38, 1 37, 1 37, 3 38, 3 0.438 0.316 0.165 0.7825 1.55 0.835 2.88 -0.193 1.01 0.849 0.07131 0.824 0.113 5.99 0.748 0.919 0.416 0.3814 2.11 0.349 12.8 0.97 0.925 0.295 0.5308 2.64 0.43 16.2 PRS_PLINK_0.001 609.2 Abnormal spermatozoa Male 46 400 11 genitourinary black 400, 46 100, 8 100, 14 100, 12 100, 12 0.033 0.152 0.828 0.08216 1.03 0.768 1.39 0.592 0.45 0.189 0.7241 1.81 0.748 4.37 0.35 0.459 0.446 0.3508 1.42 0.577 3.49 0.444 0.458 0.332 0.4792 1.56 0.636 3.82 PRS_PLINK_0.001 610 Benign mammary dysplasias Female 633 6566 11 genitourinary black 6566, 633 1642, 160 1641, 166 1641, 163 1642, 144 -0.0519 0.0423 0.219 0.6591 0.949 0.874 1.03 0.0354 0.116 0.76 0.1192 1.04 0.826 1.3 0.0156 0.116 0.893 0.04906 1.02 0.809 1.28 -0.0982 0.12 0.414 0.3832 0.906 0.716 1.15 PRS_PLINK_0.001 610.1 Cystic mastopathy Female 235 2348 11 genitourinary black 2348, 235 587, 65 587, 61 587, 60 587, 49 -0.0904 0.068 0.184 0.7352 0.914 0.8 1.04 -0.0695 0.186 0.709 0.1496 0.933 0.648 1.34 -0.0855 0.187 0.648 0.1885 0.918 0.636 1.32 -0.294 0.198 0.137 0.863 0.746 0.506 1.1 PRS_PLINK_0.001 610.2 Fibroadenosis of breast Female 77 829 11 genitourinary black 829, 77 208, 24 207, 23 207, 18 207, 12 -0.203 0.119 0.0868 1.061 0.816 0.647 1.03 -0.0337 0.303 0.911 0.04031 0.967 0.534 1.75 -0.282 0.32 0.378 0.4225 0.754 0.403 1.41 -0.63 0.356 0.0767 1.115 0.532 0.265 1.07 PRS_PLINK_0.001 610.3 Fibrosclerosis of breast Female 85 796 11 genitourinary black 796, 85 199, 15 199, 23 199, 22 199, 25 0.165 0.113 0.145 0.8387 1.18 0.945 1.47 0.335 0.34 0.324 0.4896 1.4 0.719 2.72 0.385 0.341 0.259 0.5875 1.47 0.754 2.87 0.456 0.335 0.173 0.7629 1.58 0.819 3.04 PRS_PLINK_0.001 610.4 Benign neoplasm of breast Female 360 3654 11 genitourinary black 3654, 360 914, 95 913, 89 913, 91 914, 85 -0.0668 0.0562 0.235 0.6288 0.935 0.838 1.04 -0.0615 0.154 0.689 0.1615 0.94 0.696 1.27 -0.0468 0.153 0.76 0.119 0.954 0.707 1.29 -0.115 0.156 0.462 0.3357 0.891 0.656 1.21 PRS_PLINK_0.001 610.8 Other specified benign mammary dysplasias Female 141 1760 11 genitourinary black 1760, 141 440, 31 440, 25 440, 42 440, 43 0.109 0.0872 0.21 0.6771 1.12 0.94 1.32 -0.227 0.272 0.402 0.3954 0.797 0.468 1.36 0.279 0.244 0.252 0.599 1.32 0.82 2.13 0.307 0.244 0.208 0.682 1.36 0.843 2.19 PRS_PLINK_0.001 611 Abnormal findings on mammogram or breast exam Both 396 4173 11 genitourinary black 4173, 396 1044, 91 1043, 102 1043, 105 1043, 98 0.0354 0.0525 0.5 0.3014 1.04 0.935 1.15 0.104 0.15 0.486 0.3134 1.11 0.828 1.49 0.158 0.15 0.29 0.5373 1.17 0.874 1.57 0.082 0.152 0.589 0.2296 1.09 0.806 1.46 PRS_PLINK_0.001 611.1 Abnormal mammogram Both 10 148 11 genitourinary black 148, 10 37, 4 37, 3 37, 0 37, 3 -0.0758 0.295 0.797 0.09837 0.927 0.52 1.65 -0.306 0.704 0.664 0.1777 0.737 0.185 2.93 -1.77 1.38 0.199 0.702 0.17 0.0115 2.53 0.137 0.762 0.858 0.0666 1.15 0.257 5.1 PRS_PLINK_0.001 611.3 Lump or mass in breast Both 387 4023 11 genitourinary black 4023, 387 1006, 88 1006, 99 1005, 106 1006, 94 0.0318 0.053 0.549 0.2606 1.03 0.93 1.15 0.102 0.152 0.504 0.2977 1.11 0.821 1.49 0.19 0.151 0.206 0.6851 1.21 0.9 1.63 0.0668 0.155 0.667 0.1762 1.07 0.789 1.45 PRS_PLINK_0.001 612 Breast conditions, congenital or relating to hormones Both 179 2366 11 genitourinary black 2366, 179 592, 47 591, 50 591, 39 592, 43 -0.03 0.0777 0.7 0.1551 0.97 0.833 1.13 0.0599 0.209 0.775 0.1109 1.06 0.705 1.6 -0.184 0.22 0.405 0.3928 0.832 0.54 1.28 -0.109 0.218 0.616 0.2103 0.896 0.584 1.37 PRS_PLINK_0.001 612.2 Hypertrophy of breast (Gynecomastia) Both 167 2246 11 genitourinary black 2246, 167 562, 45 561, 48 561, 34 562, 40 -0.0298 0.0791 0.706 0.151 0.971 0.831 1.13 0.055 0.214 0.797 0.0984 1.06 0.694 1.61 -0.285 0.231 0.216 0.6649 0.752 0.478 1.18 -0.161 0.224 0.473 0.3255 0.851 0.548 1.32 PRS_PLINK_0.001 612.3 Congenital anomalies of breast Both 16 198 11 genitourinary black 198, 16 50, 4 49, 2 49, 5 50, 5 -1.05 0.872 0.228 0.6428 0.349 0.0631 1.93 0.36 0.682 0.598 0.2234 1.43 0.376 5.46 0.15 0.653 0.819 0.08689 1.16 0.323 4.18 PRS_PLINK_0.001 613 Other nonmalignant breast conditions Both 393 4263 11 genitourinary black 4263, 393 1066, 91 1066, 102 1065, 106 1066, 94 0.0264 0.0533 0.62 0.2076 1.03 0.925 1.14 0.113 0.15 0.449 0.3477 1.12 0.835 1.5 0.149 0.149 0.318 0.4971 1.16 0.866 1.55 0.0309 0.153 0.84 0.07553 1.03 0.764 1.39 PRS_PLINK_0.001 613.1 Inflammatory disease of breast Both 164 1805 11 genitourinary black 1805, 164 452, 35 451, 33 451, 47 451, 49 0.132 0.083 0.112 0.9519 1.14 0.97 1.34 -0.0727 0.247 0.768 0.1144 0.93 0.573 1.51 0.286 0.23 0.215 0.6678 1.33 0.847 2.09 0.308 0.23 0.181 0.7419 1.36 0.866 2.14 PRS_PLINK_0.001 613.5 Mastodynia Both 17 206 11 genitourinary black 206, 17 52, 4 51, 7 51, 4 52, 2 -0.159 0.239 0.506 0.2956 0.853 0.534 1.36 0.398 0.627 0.526 0.2794 1.49 0.436 5.09 -0.0206 0.727 0.977 0.009947 0.98 0.236 4.07 PRS_PLINK_0.001 613.7 Other signs and symptoms in breast Both 174 1745 11 genitourinary black 1745, 174 437, 40 436, 53 436, 42 436, 39 PRS_PLINK_0.001 613.8 Other specified disorders of breast Both 63 857 11 genitourinary black 857, 63 215, 14 214, 17 214, 19 214, 13 PRS_PLINK_0.001 613.9 Breast disorder NOS Both 64 552 11 genitourinary black 552, 64 138, 20 138, 16 138, 15 138, 13 -0.198 0.127 0.121 0.919 0.821 0.64 1.05 -0.271 0.365 0.457 0.3402 0.762 0.373 1.56 PRS_PLINK_0.001 614 Inflammatory diseases of female pelvic organs Female 1299 15483 11 genitourinary black 15483, 1299 3871, 316 3871, 316 3870, 337 3871, 330 0.0254 0.0291 0.383 0.4163 1.03 0.969 1.09 0.00437 0.0826 0.958 0.0187 1 0.854 1.18 0.0705 0.0816 0.388 0.4117 1.07 0.914 1.26 0.0519 0.0821 0.527 0.2778 1.05 0.897 1.24 PRS_PLINK_0.001 614.1 Pelvic peritoneal adhesions, female (postoperative) (postinfection) Female 553 6746 11 genitourinary black 6746, 553 1687, 147 1686, 145 1686, 133 1687, 128 -0.039 0.0441 0.377 0.4238 0.962 0.882 1.05 -0.0128 0.122 0.916 0.03794 0.987 0.778 1.25 -0.096 0.125 0.441 0.3559 0.908 0.712 1.16 -0.127 0.126 0.311 0.5078 0.88 0.688 1.13 PRS_PLINK_0.001 614.3 Pelvic inflammatory disease (PID) Female 178 2238 11 genitourinary black 2238, 178 560, 49 559, 41 559, 44 560, 44 0.00606 0.079 0.939 0.02739 1.01 0.862 1.17 -0.171 0.218 0.432 0.3645 0.843 0.55 1.29 -0.0853 0.214 0.69 0.1611 0.918 0.604 1.4 -0.0456 0.215 0.832 0.07967 0.955 0.627 1.46 PRS_PLINK_0.001 614.31 Acute inflammatory pelvic disease Female 8 190 11 genitourinary black 190, 8 48, 2 47, 1 47, 3 48, 2 -0.00879 0.338 0.979 0.009109 0.991 0.511 1.92 -0.542 0.898 0.546 0.263 0.581 0.1 3.38 0.583 0.806 0.47 0.3281 1.79 0.369 8.69 -0.0168 0.818 0.984 0.007152 0.983 0.198 4.89 PRS_PLINK_0.001 614.32 Chronic inflammatory pelvic disease Female 91 1113 11 genitourinary black 1113, 91 279, 21 278, 19 278, 27 278, 24 0.0915 0.109 0.403 0.3945 1.1 0.884 1.36 -0.0608 0.319 0.849 0.07122 0.941 0.503 1.76 0.238 0.3 0.429 0.3673 1.27 0.704 2.29 0.187 0.307 0.542 0.266 1.21 0.66 2.2 PRS_PLINK_0.001 614.33 Pelvic inflammatory disease, NOS Female 74 920 11 genitourinary black 920, 74 230, 20 230, 19 230, 18 230, 17 -0.0358 0.122 0.769 0.1139 0.965 0.759 1.23 0.00667 0.325 0.984 0.007177 1.01 0.533 1.9 -0.0353 0.331 0.915 0.03844 0.965 0.504 1.85 -0.112 0.335 0.739 0.1316 0.894 0.464 1.72 PRS_PLINK_0.001 614.4 Inflammatory diseases of uterus, except cervix Female 63 751 11 genitourinary black 751, 63 188, 9 188, 14 187, 20 188, 20 0.256 0.134 0.0558 1.253 1.29 0.994 1.68 0.469 0.421 0.266 0.5755 1.6 0.7 3.65 0.796 0.4 0.0465 1.333 2.22 1.01 4.85 0.8 0.409 0.0505 1.297 2.22 0.998 4.96 PRS_PLINK_0.001 614.5 Inflammatory disease of cervix, vagina, and vulva Female 618 7117 11 genitourinary black 7117, 618 1780, 148 1779, 141 1779, 164 1779, 165 0.0593 0.0422 0.16 0.7946 1.06 0.977 1.15 -0.0522 0.122 0.669 0.1748 0.949 0.747 1.21 0.102 0.118 0.389 0.4099 1.11 0.878 1.4 0.114 0.118 0.335 0.4747 1.12 0.889 1.41 PRS_PLINK_0.001 614.51 Cervicitis and endocervicitis Female 304 3576 11 genitourinary black 3576, 304 894, 86 894, 64 894, 77 894, 77 -0.0347 0.0593 0.558 0.253 0.966 0.86 1.08 -0.3 0.17 0.0782 1.107 0.741 0.53 1.03 -0.128 0.164 0.435 0.3616 0.88 0.639 1.21 -0.127 0.163 0.438 0.3585 0.881 0.639 1.21 PRS_PLINK_0.001 614.52 Vaginitis and vulvovaginitis Female 97 1162 11 genitourinary black 1162, 97 291, 8 290, 25 290, 35 291, 29 0.331 0.108 0.00226 2.646 1.39 1.13 1.72 1.17 0.396 0.00326 2.487 3.21 1.48 6.97 1.45 0.382 0.000141 3.851 4.28 2.02 9.05 1.28 0.39 0.00106 2.973 3.58 1.67 7.7 PRS_PLINK_0.001 614.53 Cyst or abscess of Bartholin's gland Female 191 2028 11 genitourinary black 2028, 191 507, 41 507, 53 507, 45 507, 52 0.0873 0.0752 0.245 0.6101 1.09 0.942 1.26 0.218 0.216 0.313 0.5045 1.24 0.814 1.9 0.118 0.222 0.594 0.2262 1.13 0.728 1.74 0.274 0.217 0.206 0.6852 1.31 0.86 2.01 PRS_PLINK_0.001 614.54 Abscess or ulceration of vulva Female 48 723 11 genitourinary black 723, 48 181, 8 181, 7 180, 12 181, 21 0.444 0.158 0.00501 2.3 1.56 1.14 2.13 -0.148 0.487 0.761 0.1183 0.863 0.332 2.24 0.358 0.438 0.413 0.3842 1.43 0.607 3.37 0.962 0.41 0.0189 1.723 2.62 1.17 5.85 PRS_PLINK_0.001 615 Endometriosis Female 983 11050 11 genitourinary black 11050, 983 2763, 206 2762, 247 2762, 260 2763, 270 0.0857 0.0338 0.0113 1.948 1.09 1.02 1.16 0.189 0.0979 0.0534 1.272 1.21 0.997 1.46 0.227 0.097 0.0191 1.719 1.26 1.04 1.52 0.281 0.0965 0.00358 2.447 1.32 1.1 1.6 PRS_PLINK_0.001 617 Disorders secondary to childbirth, surgery, trauma Female 54 782 11 genitourinary black 782, 54 196, 13 195, 19 195, 8 196, 14 -0.0305 0.133 0.819 0.08685 0.97 0.747 1.26 0.411 0.368 0.263 0.5792 1.51 0.734 3.1 -0.5 0.45 0.266 0.5746 0.606 0.251 1.46 0.0725 0.394 0.854 0.06862 1.08 0.497 2.33 PRS_PLINK_0.001 618 Genital prolapse Female 2592 29994 11 genitourinary black 29994, 2592 7498, 656 7498, 690 7498, 634 7499, 612 -0.029 0.0205 0.157 0.8043 0.971 0.933 1.01 0.0516 0.0569 0.364 0.4383 1.05 0.942 1.18 -0.0293 0.0582 0.615 0.2113 0.971 0.867 1.09 -0.0569 0.0587 0.332 0.4783 0.945 0.842 1.06 PRS_PLINK_0.001 618.1 Prolapse of vaginal walls Female 1583 18813 11 genitourinary black 18813, 1583 4704, 409 4703, 411 4703, 383 4703, 380 -0.0237 0.0263 0.368 0.4341 0.977 0.928 1.03 0.00162 0.0728 0.982 0.007768 1 0.868 1.16 -0.0634 0.0742 0.393 0.4053 0.939 0.811 1.09 -0.0643 0.0745 0.388 0.4111 0.938 0.81 1.09 PRS_PLINK_0.001 618.2 Uterine/Uterovaginal prolapse Female 1234 13805 11 genitourinary black 13805, 1234 3451, 318 3451, 311 3451, 307 3451, 298 -0.029 0.0298 0.331 0.4805 0.971 0.916 1.03 -0.0165 0.0832 0.843 0.07423 0.984 0.836 1.16 -0.0238 0.0836 0.776 0.1103 0.976 0.829 1.15 -0.0452 0.0843 0.592 0.2276 0.956 0.81 1.13 PRS_PLINK_0.001 618.5 Prolapse of vaginal vault after hysterectomy Female 130 1302 11 genitourinary black 1302, 130 326, 26 325, 45 325, 21 326, 38 0.0101 0.0907 0.911 0.04038 1.01 0.846 1.21 0.524 0.255 0.0394 1.404 1.69 1.03 2.78 -0.189 0.296 0.523 0.2818 0.828 0.463 1.48 0.452 0.265 0.0873 1.059 1.57 0.936 2.64 PRS_PLINK_0.001 618.6 Vaginal enterocele, congenital or acquired Female 128 1754 11 genitourinary black 1754, 128 439, 29 438, 33 438, 33 439, 33 -0.0384 0.0901 0.67 0.1738 0.962 0.807 1.15 0.15 0.26 0.562 0.2502 1.16 0.699 1.93 0.13 0.26 0.617 0.2097 1.14 0.685 1.89 0.111 0.26 0.67 0.1739 1.12 0.671 1.86 PRS_PLINK_0.001 619 Noninflammatory female genital disorders Female 2109 23263 11 genitourinary black 23263, 2109 5815, 466 5816, 576 5815, 526 5816, 541 0.0581 0.0231 0.0118 1.928 1.06 1.01 1.11 0.211 0.065 0.00114 2.943 1.24 1.09 1.4 0.121 0.0664 0.0684 1.165 1.13 0.991 1.29 0.146 0.0661 0.0271 1.567 1.16 1.02 1.32 PRS_PLINK_0.001 619.1 Noninflammatory disorders of ovary, fallopian tube, and broad ligament Female 176 1935 11 genitourinary black 1935, 176 484, 34 484, 45 483, 46 484, 51 0.144 0.0817 0.0775 1.111 1.16 0.984 1.36 0.269 0.233 0.25 0.6022 1.31 0.828 2.07 0.315 0.232 0.175 0.7577 1.37 0.869 2.16 0.391 0.229 0.088 1.055 1.48 0.943 2.32 PRS_PLINK_0.001 619.2 Disorders of uterus, NEC Female 802 8838 11 genitourinary black 8838, 802 2209, 187 2209, 200 2209, 205 2210, 210 0.0651 0.0373 0.081 1.091 1.07 0.992 1.15 0.0616 0.106 0.561 0.2512 1.06 0.864 1.31 0.0875 0.106 0.408 0.3896 1.09 0.887 1.34 0.106 0.105 0.315 0.5023 1.11 0.905 1.37 PRS_PLINK_0.001 619.3 Noninflammatory disorders of cervix Female 721 7726 11 genitourinary black 7726, 721 1931, 158 1931, 208 1931, 182 1932, 173 0.0289 0.0391 0.461 0.3362 1.03 0.953 1.11 0.281 0.11 0.0108 1.968 1.32 1.07 1.64 0.139 0.113 0.219 0.6589 1.15 0.921 1.43 0.083 0.115 0.47 0.3279 1.09 0.868 1.36 PRS_PLINK_0.001 619.4 Noninflammatory disorders of vagina Female 424 4592 11 genitourinary black 4592, 424 1147, 95 1148, 117 1148, 108 1148, 104 0.0182 0.0515 0.724 0.14 1.02 0.921 1.13 0.215 0.144 0.135 0.8706 1.24 0.936 1.64 0.136 0.146 0.352 0.4536 1.15 0.86 1.53 0.0957 0.148 0.518 0.2855 1.1 0.823 1.47 PRS_PLINK_0.001 619.5 Noninflammatory disorders of vulva and perineum Female 320 3526 11 genitourinary black 3526, 320 882, 75 881, 91 881, 77 882, 77 0.0203 0.0603 0.736 0.1329 1.02 0.907 1.15 0.191 0.162 0.239 0.6207 1.21 0.881 1.66 0.0243 0.168 0.885 0.05307 1.02 0.737 1.42 0.0183 0.169 0.914 0.03904 1.02 0.731 1.42 PRS_PLINK_0.001 620 Dysplasia of female genital organs Female 16 158 11 genitourinary black 158, 16 40, 4 39, 5 39, 3 40, 4 -0.374 0.271 0.168 0.7743 0.688 0.404 1.17 0.367 0.699 0.6 0.2219 1.44 0.367 5.68 0.0591 0.781 0.94 0.02705 1.06 0.23 4.9 -0.125 0.781 0.873 0.05908 0.882 0.191 4.08 PRS_PLINK_0.001 621 Endometrial hyperplasia Female 281 2913 11 genitourinary black 2913, 281 729, 73 728, 76 728, 65 728, 67 -0.00415 0.0623 0.947 0.02372 0.996 0.881 1.13 0.047 0.172 0.784 0.1057 1.05 0.749 1.47 -0.087 0.177 0.624 0.2047 0.917 0.647 1.3 -0.0869 0.176 0.622 0.206 0.917 0.649 1.3 PRS_PLINK_0.001 622 Polyp of female genital organs Female 2773 27717 11 genitourinary black 27717, 2773 6929, 679 6929, 751 6929, 655 6929, 688 0.00244 0.0201 0.903 0.04415 1 0.964 1.04 0.101 0.0556 0.069 1.161 1.11 0.992 1.23 -0.0314 0.0574 0.584 0.2334 0.969 0.866 1.08 0.0104 0.0569 0.855 0.06814 1.01 0.904 1.13 PRS_PLINK_0.001 622.1 Polyp of corpus uteri Female 2054 20820 11 genitourinary black 20820, 2054 5205, 499 5205, 549 5205, 491 5205, 515 0.00798 0.0234 0.733 0.1346 1.01 0.963 1.06 0.0957 0.0648 0.14 0.8541 1.1 0.969 1.25 -0.00775 0.0666 0.907 0.04222 0.992 0.871 1.13 0.0348 0.066 0.598 0.2237 1.04 0.91 1.18 PRS_PLINK_0.001 622.2 Mucous polyp of cervix Female 929 8888 11 genitourinary black 8888, 929 2222, 217 2222, 269 2222, 214 2222, 229 0.00667 0.0348 0.848 0.07162 1.01 0.94 1.08 0.213 0.0959 0.0265 1.578 1.24 1.03 1.49 -0.0228 0.101 0.822 0.08536 0.977 0.802 1.19 0.0311 0.0996 0.755 0.1221 1.03 0.849 1.25 PRS_PLINK_0.001 623 Hypertrophy of female genital organs Female 321 3395 11 genitourinary black 3395, 321 849, 85 849, 80 848, 84 849, 72 -0.0151 0.0577 0.794 0.1002 0.985 0.88 1.1 -0.081 0.162 0.618 0.2089 0.922 0.671 1.27 -0.0208 0.161 0.897 0.04711 0.979 0.714 1.34 -0.18 0.167 0.28 0.5534 0.835 0.602 1.16 PRS_PLINK_0.001 624 Symptoms involving female genital tract Female 173 1982 11 genitourinary black 1982, 173 496, 50 495, 30 495, 50 496, 43 0.0343 0.0791 0.664 0.1775 1.03 0.886 1.21 -0.462 0.236 0.0501 1.3 0.63 0.397 1 0.0382 0.21 0.856 0.06765 1.04 0.688 1.57 -0.104 0.216 0.632 0.1994 0.901 0.59 1.38 PRS_PLINK_0.001 624.1 Dystrophy of female genital tract Female 48 580 11 genitourinary black 580, 48 145, 15 145, 10 145, 16 145, 7 -0.114 0.15 0.447 0.3498 0.892 0.665 1.2 -0.317 0.409 0.439 0.3572 0.729 0.327 1.63 0.174 0.382 0.648 0.1883 1.19 0.563 2.52 -0.576 0.449 0.2 0.6988 0.562 0.233 1.36 PRS_PLINK_0.001 624.2 Atrophy of female genital tract Female 103 1118 11 genitourinary black 1118, 103 280, 33 279, 18 279, 22 280, 30 -0.00888 0.101 0.93 0.03168 0.991 0.814 1.21 -0.571 0.298 0.0555 1.256 0.565 0.315 1.01 -0.341 0.285 0.232 0.6348 0.711 0.407 1.24 -0.0422 0.266 0.874 0.05867 0.959 0.57 1.61 PRS_PLINK_0.001 624.9 stress incontinence, female Female 1225 15344 11 genitourinary black 15344, 1225 3836, 303 3836, 310 3836, 307 3836, 305 0.00593 0.03 0.843 0.07402 1.01 0.948 1.07 0.0256 0.0839 0.76 0.1192 1.03 0.87 1.21 0.0296 0.0842 0.726 0.1393 1.03 0.873 1.21 0.0313 0.0846 0.712 0.1477 1.03 0.874 1.22 PRS_PLINK_0.001 625 Pain and other symptoms associated with female genital organs Female 663 7857 11 genitourinary black 7857, 663 1965, 152 1964, 166 1964, 158 1964, 187 0.0808 0.0411 0.0493 1.308 1.08 1 1.18 0.0889 0.116 0.445 0.3515 1.09 0.87 1.37 0.0422 0.118 0.721 0.1422 1.04 0.828 1.31 0.188 0.114 0.0989 1.005 1.21 0.965 1.51 PRS_PLINK_0.001 625.1 Dyspareunia Female 248 3240 11 genitourinary black 3240, 248 810, 59 810, 59 810, 58 810, 72 0.083 0.0667 0.213 0.6709 1.09 0.953 1.24 -0.00593 0.189 0.975 0.011 0.994 0.686 1.44 -0.00201 0.19 0.992 0.003681 0.998 0.688 1.45 0.171 0.182 0.346 0.4614 1.19 0.831 1.69 PRS_PLINK_0.001 626 Disorders of menstruation and other abnormal bleeding from female genital tract Female 4001 32520 11 genitourinary black 32520, 4001 8130, 947 8130, 1034 8130, 974 8130, 1046 0.042 0.017 0.0136 1.866 1.04 1.01 1.08 0.0879 0.0478 0.0658 1.182 1.09 0.994 1.2 0.028 0.0485 0.563 0.2493 1.03 0.935 1.13 0.102 0.048 0.0329 1.483 1.11 1.01 1.22 PRS_PLINK_0.001 626.1 Irregular menstrual cycle/bleeding Female 3470 31274 11 genitourinary black 31274, 3470 7819, 827 7818, 904 7818, 854 7819, 885 0.0325 0.0181 0.0727 1.139 1.03 0.997 1.07 0.0886 0.0508 0.081 1.091 1.09 0.989 1.21 0.0298 0.0515 0.563 0.2493 1.03 0.931 1.14 0.07 0.0513 0.172 0.764 1.07 0.97 1.19 PRS_PLINK_0.001 626.11 Absent or infrequent menstruation Female 21 326 11 genitourinary black 326, 21 82, 4 81, 9 81, 3 82, 5 0.168 0.224 0.455 0.3424 1.18 0.762 1.84 0.668 0.57 0.241 0.6174 1.95 0.638 5.95 -0.262 0.68 0.7 0.1549 0.77 0.203 2.92 0.129 0.627 0.837 0.07723 1.14 0.333 3.89 PRS_PLINK_0.001 626.12 Excessive or frequent menstruation Female 2267 25618 11 genitourinary black 25618, 2267 6405, 538 6404, 598 6404, 563 6405, 568 0.019 0.0222 0.392 0.4062 1.02 0.976 1.06 0.109 0.062 0.0786 1.105 1.12 0.988 1.26 0.0419 0.0629 0.505 0.2965 1.04 0.922 1.18 0.0611 0.063 0.332 0.4787 1.06 0.94 1.2 PRS_PLINK_0.001 626.13 Irregular menstrual cycle Female 494 5369 11 genitourinary black 5369, 494 1343, 127 1342, 127 1342, 113 1342, 127 0.0209 0.0483 0.665 0.1769 1.02 0.929 1.12 0.0167 0.131 0.898 0.04651 1.02 0.787 1.31 -0.0995 0.135 0.461 0.3368 0.905 0.695 1.18 0.0163 0.132 0.901 0.04505 1.02 0.785 1.32 PRS_PLINK_0.001 626.14 Irregular menstrual bleeding Female 1014 10779 11 genitourinary black 10779, 1014 2695, 236 2695, 248 2694, 259 2695, 271 0.0555 0.0332 0.0942 1.026 1.06 0.991 1.13 0.0536 0.0947 0.572 0.2428 1.06 0.876 1.27 0.0949 0.0939 0.312 0.5054 1.1 0.915 1.32 0.153 0.0934 0.102 0.9903 1.16 0.97 1.4 PRS_PLINK_0.001 626.2 Dysmenorrhea Female 387 4942 11 genitourinary black 4942, 387 1236, 85 1235, 89 1235, 94 1236, 119 0.127 0.0536 0.0174 1.759 1.14 1.02 1.26 0.0737 0.156 0.637 0.1959 1.08 0.793 1.46 0.0928 0.154 0.548 0.2616 1.1 0.811 1.48 0.362 0.148 0.0146 1.834 1.44 1.07 1.92 PRS_PLINK_0.001 626.4 Premenstrual tension syndromes Female 27 447 11 genitourinary black 447, 27 112, 8 112, 4 111, 6 112, 9 0.135 0.205 0.512 0.2907 1.14 0.765 1.71 -0.593 0.561 0.291 0.536 0.553 0.184 1.66 -0.221 0.513 0.667 0.1762 0.802 0.294 2.19 0.252 0.489 0.607 0.2168 1.29 0.493 3.36 PRS_PLINK_0.001 626.8 Infertility, female Female 405 3754 11 genitourinary black 3754, 405 939, 84 938, 104 938, 105 939, 112 0.121 0.0537 0.0247 1.607 1.13 1.02 1.25 0.201 0.153 0.19 0.7206 1.22 0.905 1.65 0.215 0.153 0.161 0.7924 1.24 0.918 1.67 0.284 0.152 0.0615 1.211 1.33 0.986 1.79 PRS_PLINK_0.001 627 Menopausal and postmenopausal disorders Female 2494 26982 11 genitourinary black 26982, 2494 6745, 634 6745, 612 6745, 602 6746, 646 0.00695 0.0211 0.742 0.1297 1.01 0.966 1.05 -0.0368 0.0592 0.534 0.2721 0.964 0.858 1.08 -0.0548 0.0595 0.357 0.4474 0.947 0.842 1.06 0.0151 0.0587 0.797 0.09845 1.02 0.905 1.14 PRS_PLINK_0.001 627.1 Postmenopausal bleeding Female 2159 23326 11 genitourinary black 23326, 2159 5831, 547 5831, 525 5831, 525 5832, 562 0.0129 0.0227 0.569 0.245 1.01 0.969 1.06 -0.0432 0.0638 0.498 0.3026 0.958 0.845 1.09 -0.0443 0.0639 0.489 0.3111 0.957 0.844 1.08 0.0259 0.0631 0.681 0.1667 1.03 0.907 1.16 PRS_PLINK_0.001 627.2 Symptomatic menopause Female 43 460 11 genitourinary black 460, 43 115, 11 115, 11 115, 11 115, 10 -0.00339 0.164 0.984 0.007208 0.997 0.722 1.38 0.0389 0.433 0.928 0.03227 1.04 0.445 2.43 0.0617 0.429 0.886 0.05273 1.06 0.459 2.46 -0.0585 0.443 0.895 0.04815 0.943 0.396 2.25 PRS_PLINK_0.001 627.3 Postmenopausal atrophic vaginitis Female 232 2670 11 genitourinary black 2670, 232 668, 57 667, 51 667, 67 668, 57 0.0121 0.0676 0.858 0.0664 1.01 0.887 1.16 -0.108 0.198 0.586 0.2317 0.898 0.609 1.32 0.153 0.187 0.416 0.3813 1.16 0.807 1.68 0.0199 0.194 0.918 0.03693 1.02 0.697 1.49 PRS_PLINK_0.001 627.4 Premenopausal menorrhagia Female 85 841 11 genitourinary black 841, 85 211, 24 210, 28 210, 17 210, 16 -0.189 0.113 0.0943 1.025 0.828 0.664 1.03 0.123 0.293 0.673 0.1719 1.13 0.638 2.01 -0.331 0.324 0.307 0.5123 0.718 0.38 1.36 -0.394 0.33 0.233 0.6317 0.675 0.353 1.29 PRS_PLINK_0.001 628 Ovarian cyst Female 1098 12761 11 genitourinary black 12761, 1098 3191, 257 3190, 276 3190, 288 3190, 277 0.0188 0.0315 0.55 0.2593 1.02 0.958 1.08 0.0791 0.0901 0.38 0.4199 1.08 0.907 1.29 0.115 0.0895 0.197 0.7052 1.12 0.942 1.34 0.0833 0.0904 0.357 0.4477 1.09 0.91 1.3 PRS_PLINK_0.001 634 Miscarriage; stillbirth Female 1398 9828 12 pregnancy complications royalblue4 9828, 1398 2457, 337 2457, 348 2457, 340 2457, 373 0.0614 0.0292 0.0356 1.449 1.06 1 1.13 0.0339 0.082 0.679 0.1681 1.03 0.881 1.21 0.00689 0.0825 0.933 0.02989 1.01 0.857 1.18 0.115 0.0812 0.158 0.801 1.12 0.956 1.31 PRS_PLINK_0.001 634.1 Missed abortion/Hydatidiform mole Female 318 3013 12 pregnancy complications royalblue4 3013, 318 754, 76 753, 87 753, 84 753, 71 -0.0029 0.0602 0.962 0.01703 0.997 0.886 1.12 0.15 0.165 0.363 0.4395 1.16 0.841 1.61 0.0883 0.166 0.595 0.2255 1.09 0.789 1.51 -0.0932 0.174 0.591 0.2281 0.911 0.648 1.28 PRS_PLINK_0.001 634.3 Ectopic pregnancy Female 78 892 12 pregnancy complications royalblue4 892, 78 223, 13 223, 15 223, 22 223, 28 0.349 0.125 0.0052 2.284 1.42 1.11 1.81 0.0894 0.375 0.812 0.09069 1.09 0.525 2.28 0.473 0.351 0.178 0.7502 1.6 0.807 3.19 0.694 0.343 0.0429 1.367 2 1.02 3.92 PRS_PLINK_0.001 635 Hemorrhage during pregnancy; childbirth and postpartum Female 524 4654 12 pregnancy complications royalblue4 4654, 524 1164, 124 1163, 126 1163, 125 1164, 149 0.0681 0.0467 0.145 0.8381 1.07 0.977 1.17 0.00868 0.133 0.948 0.02326 1.01 0.778 1.31 0.0107 0.133 0.936 0.02873 1.01 0.779 1.31 0.177 0.129 0.167 0.7761 1.19 0.928 1.54 PRS_PLINK_0.001 635.2 Antepartum hemorrhage, abruptio placentae, and placenta previa Female 245 2277 12 pregnancy complications royalblue4 2277, 245 570, 50 569, 60 569, 62 569, 73 0.0957 0.068 0.16 0.7971 1.1 0.963 1.26 0.175 0.198 0.379 0.4215 1.19 0.807 1.76 0.215 0.197 0.276 0.5586 1.24 0.842 1.83 0.371 0.192 0.0528 1.277 1.45 0.995 2.11 PRS_PLINK_0.001 635.3 Placenta previa and abruptio placenta Female 324 3278 12 pregnancy complications royalblue4 3278, 324 820, 80 819, 78 819, 77 820, 89 0.0475 0.0585 0.417 0.3798 1.05 0.935 1.18 -0.036 0.166 0.828 0.08208 0.965 0.697 1.33 -0.0298 0.166 0.858 0.06664 0.971 0.7 1.35 0.097 0.162 0.548 0.261 1.1 0.803 1.51 PRS_PLINK_0.001 636 Early or threatened labor; hemorrhage in early pregnancy Female 585 5315 12 pregnancy complications royalblue4 5315, 585 1329, 142 1329, 145 1328, 147 1329, 151 0.0569 0.0444 0.2 0.7 1.06 0.97 1.15 0.0239 0.124 0.847 0.07208 1.02 0.803 1.31 0.0413 0.124 0.739 0.1314 1.04 0.817 1.33 0.0524 0.124 0.672 0.1729 1.05 0.827 1.34 PRS_PLINK_0.001 636.2 Early onset of delivery Female 164 1609 12 pregnancy complications royalblue4 1609, 164 403, 43 402, 42 402, 47 402, 32 -0.0879 0.0838 0.295 0.5307 0.916 0.777 1.08 -0.0123 0.226 0.957 0.01928 0.988 0.635 1.54 0.101 0.221 0.648 0.1884 1.11 0.718 1.71 -0.28 0.242 0.247 0.6079 0.756 0.47 1.21 PRS_PLINK_0.001 636.3 Hemorrhage in early pregnancy Female 239 2847 12 pregnancy complications royalblue4 2847, 239 712, 55 712, 64 711, 49 712, 71 0.127 0.0691 0.0651 1.186 1.14 0.992 1.3 0.136 0.189 0.472 0.3265 1.15 0.791 1.66 -0.113 0.201 0.575 0.2405 0.893 0.602 1.33 0.234 0.186 0.209 0.6802 1.26 0.877 1.82 PRS_PLINK_0.001 638 Other high-risk pregnancy Female 14 188 12 pregnancy complications royalblue4 188, 14 47, 3 47, 2 47, 5 47, 4 0.376 0.274 0.171 0.7677 1.46 0.851 2.49 0.161 0.886 0.855 0.06778 1.18 0.207 6.67 0.243 0.726 0.738 0.1319 1.27 0.307 5.29 0.29 0.755 0.701 0.1542 1.34 0.304 5.86 PRS_PLINK_0.001 642 Hypertension complicating pregnancy, childbirth, and the puerperium Female 300 2935 12 pregnancy complications royalblue4 2935, 300 734, 78 734, 71 733, 75 734, 76 -0.00657 0.0623 0.916 0.03812 0.993 0.879 1.12 -0.102 0.172 0.552 0.2583 0.903 0.645 1.26 -0.0433 0.17 0.798 0.09783 0.958 0.687 1.34 -0.0115 0.169 0.946 0.02409 0.989 0.709 1.38 PRS_PLINK_0.001 642.1 Preeclampsia and eclampsia Female 82 818 12 pregnancy complications royalblue4 818, 82 205, 17 204, 22 204, 23 205, 20 0.0588 0.12 0.625 0.2042 1.06 0.838 1.34 0.198 0.331 0.551 0.2589 1.22 0.637 2.33 0.399 0.331 0.228 0.6429 1.49 0.779 2.85 0.216 0.336 0.52 0.2837 1.24 0.642 2.4 PRS_PLINK_0.001 643 Excessive vomiting in pregnancy Female 65 573 12 pregnancy complications royalblue4 573, 65 144, 14 143, 21 143, 13 143, 17 -0.00512 0.134 0.97 0.0134 0.995 0.764 1.29 0.362 0.354 0.306 0.5137 1.44 0.717 2.88 -0.00754 0.39 0.985 0.006746 0.992 0.462 2.13 0.102 0.382 0.789 0.1031 1.11 0.524 2.34 PRS_PLINK_0.001 643.1 Hyperemesis gravidarum Female 46 397 12 pregnancy complications royalblue4 397, 46 100, 12 99, 14 99, 9 99, 11 0.0407 0.161 0.801 0.09639 1.04 0.759 1.43 0.17 0.41 0.679 0.1682 1.18 0.531 2.65 -0.169 0.456 0.711 0.1479 0.845 0.346 2.06 -0.204 0.446 0.648 0.1884 0.816 0.34 1.96 PRS_PLINK_0.001 645 Late pregnancy and failed induction Female 371 3323 12 pregnancy complications royalblue4 3323, 371 831, 86 831, 88 830, 89 831, 108 0.0974 0.0556 0.0796 1.099 1.1 0.989 1.23 0.0209 0.159 0.895 0.04817 1.02 0.748 1.39 0.0196 0.158 0.902 0.04497 1.02 0.748 1.39 0.25 0.153 0.102 0.9916 1.28 0.952 1.73 PRS_PLINK_0.001 646 Other complications of pregnancy NEC Female 548 5584 12 pregnancy complications royalblue4 5584, 548 1396, 149 1396, 141 1396, 127 1396, 131 -0.054 0.0454 0.234 0.6307 0.947 0.867 1.04 -0.0547 0.123 0.658 0.1821 0.947 0.743 1.21 -0.177 0.127 0.163 0.7891 0.838 0.654 1.07 -0.13 0.126 0.301 0.5216 0.878 0.686 1.12 PRS_PLINK_0.001 647 Infectious and parasitic complications affecting pregnancy Female 18 186 12 pregnancy complications royalblue4 186, 18 47, 1 46, 0 46, 10 47, 7 0.587 0.269 0.029 1.538 1.8 1.06 3.04 0.336 1.25 0.788 0.1034 1.4 0.121 16.2 2.05 0.883 0.0203 1.692 7.76 1.37 43.8 1.6 0.867 0.0647 1.189 4.96 0.907 27.1 PRS_PLINK_0.001 647.1 Infections of genitourinary tract during pregnancy Female 57 708 12 pregnancy complications royalblue4 708, 57 177, 11 177, 18 177, 15 177, 13 0.0612 0.136 0.652 0.186 1.06 0.815 1.39 0.476 0.386 0.218 0.6622 1.61 0.755 3.43 0.284 0.398 0.475 0.3237 1.33 0.61 2.9 0.191 0.41 0.641 0.193 1.21 0.542 2.71 PRS_PLINK_0.001 649 Other conditions or status of the mother complicating pregnancy, childbirth, or the puerperium Female 31 290 12 pregnancy complications royalblue4 290, 31 73, 13 72, 9 72, 4 73, 5 -0.374 0.191 0.0501 1.3 0.688 0.473 1 -0.492 0.477 0.303 0.5192 0.612 0.24 1.56 -1.21 0.578 0.0369 1.433 0.299 0.0964 0.929 -1.02 0.526 0.0516 1.288 0.359 0.128 1.01 PRS_PLINK_0.001 649.1 Diabetes or abnormal glucose tolerance complicating pregnancy Female 45 539 12 pregnancy complications royalblue4 539, 45 135, 9 135, 13 134, 10 135, 13 0.105 0.162 0.516 0.2877 1.11 0.809 1.53 0.334 0.43 0.437 0.3597 1.4 0.602 3.24 0.128 0.461 0.781 0.1074 1.14 0.461 2.8 0.518 0.438 0.237 0.6258 1.68 0.712 3.96 PRS_PLINK_0.001 650 Normal delivery Female 517 5050 12 pregnancy complications royalblue4 5050, 517 1263, 126 1262, 125 1262, 140 1263, 126 0.00886 0.0471 0.851 0.07018 1.01 0.92 1.11 -0.00589 0.132 0.964 0.01574 0.994 0.768 1.29 0.109 0.129 0.399 0.3989 1.11 0.866 1.43 0.0088 0.132 0.947 0.02374 1.01 0.779 1.31 PRS_PLINK_0.001 651 Multiple gestation Female 105 914 12 pregnancy complications royalblue4 914, 105 229, 23 228, 28 228, 31 229, 23 0.0681 0.105 0.518 0.2856 1.07 0.871 1.32 0.24 0.292 0.411 0.3862 1.27 0.717 2.26 0.286 0.285 0.317 0.4994 1.33 0.761 2.33 0.00201 0.302 0.995 0.002311 1 0.555 1.81 PRS_PLINK_0.001 652 Malposition and malpresentation of fetus or obstruction Female 473 4369 12 pregnancy complications royalblue4 4369, 473 1093, 118 1092, 129 1092, 117 1092, 109 -0.0192 0.0486 0.692 0.1599 0.981 0.892 1.08 0.0804 0.134 0.549 0.2602 1.08 0.833 1.41 -0.0148 0.137 0.914 0.03912 0.985 0.753 1.29 -0.094 0.14 0.502 0.2994 0.91 0.692 1.2 PRS_PLINK_0.001 653 Problems associated with amniotic cavity and membranes Female 384 3680 12 pregnancy complications royalblue4 3680, 384 920, 92 920, 95 920, 103 920, 94 -0.00327 0.0544 0.952 0.02132 0.997 0.896 1.11 0.0199 0.153 0.897 0.0474 1.02 0.756 1.38 0.109 0.15 0.469 0.3291 1.11 0.831 1.5 0.0207 0.153 0.893 0.04931 1.02 0.756 1.38 PRS_PLINK_0.001 654 Other and unspecified complications of birth; puerperium affecting management of mother Female 18 205 12 pregnancy complications royalblue4 205, 18 52, 5 51, 3 51, 3 51, 7 0.0188 0.23 0.935 0.02934 1.02 0.65 1.6 -0.542 0.676 0.423 0.3741 0.582 0.155 2.19 -0.332 0.682 0.627 0.2027 0.718 0.188 2.73 0.36 0.629 0.567 0.2462 1.43 0.418 4.92 PRS_PLINK_0.001 655 Known or suspected fetal abnormality affecting management of mother Female 1215 7855 12 pregnancy complications royalblue4 7855, 1215 1964, 315 1964, 299 1963, 287 1964, 314 0.00162 0.0316 0.959 0.01813 1 0.941 1.07 -0.0485 0.0875 0.579 0.2371 0.953 0.802 1.13 -0.1 0.0883 0.257 0.5899 0.905 0.761 1.08 0.00318 0.0869 0.971 0.01288 1 0.846 1.19 PRS_PLINK_0.001 656 Other perinatal conditions of fetus or newborn Both 26 282 12 pregnancy complications royalblue4 282, 26 71, 3 70, 9 70, 4 71, 10 0.376 0.205 0.0666 1.177 1.46 0.975 2.18 0.829 0.61 0.175 0.758 2.29 0.692 7.58 0.323 0.703 0.646 0.1897 1.38 0.348 5.48 0.91 0.601 0.13 0.887 2.49 0.765 8.07 PRS_PLINK_0.001 661 Fetal distress and abnormal forces of labor Female 707 4734 12 pregnancy complications royalblue4 4734, 707 1184, 180 1183, 165 1183, 177 1184, 185 0.0309 0.0413 0.455 0.3423 1.03 0.951 1.12 -0.101 0.116 0.383 0.4167 0.904 0.721 1.13 -0.0204 0.114 0.858 0.06662 0.98 0.784 1.22 0.0365 0.113 0.747 0.1268 1.04 0.831 1.29 PRS_PLINK_0.001 663 Umbilical cord complications during labor and delivery Female 138 1387 12 pregnancy complications royalblue4 1387, 138 347, 41 347, 32 346, 36 347, 29 -0.0732 0.0892 0.412 0.3851 0.929 0.78 1.11 -0.258 0.246 0.294 0.5322 0.772 0.477 1.25 -0.117 0.239 0.624 0.2046 0.89 0.557 1.42 -0.328 0.25 0.19 0.7205 0.721 0.441 1.18 PRS_PLINK_0.001 665 Obstetrical/birth trauma Female 1573 7729 12 pregnancy complications royalblue4 7729, 1573 1933, 401 1932, 407 1932, 394 1932, 371 -0.0191 0.0286 0.506 0.2961 0.981 0.928 1.04 0.0129 0.0792 0.87 0.06035 1.01 0.867 1.18 -0.0208 0.0798 0.794 0.1002 0.979 0.838 1.15 -0.0378 0.0813 0.642 0.1923 0.963 0.821 1.13 PRS_PLINK_0.001 669 Complications of labor and delivery NEC Female 741 5454 12 pregnancy complications royalblue4 5454, 741 1364, 172 1363, 192 1363, 182 1364, 195 0.0289 0.0398 0.468 0.3297 1.03 0.952 1.11 0.109 0.112 0.33 0.4817 1.12 0.896 1.39 0.052 0.113 0.646 0.1896 1.05 0.844 1.32 0.135 0.112 0.23 0.6392 1.14 0.919 1.42 PRS_PLINK_0.001 671 Venous/cerebrovascular complications embolism in pregnancy and the puerperium Female 49 423 12 pregnancy complications royalblue4 423, 49 106, 11 106, 10 105, 12 106, 16 0.206 0.152 0.177 0.753 1.23 0.912 1.65 0.000537 0.443 0.999 0.00042 1 0.42 2.39 0.0853 0.423 0.84 0.07562 1.09 0.475 2.5 0.384 0.409 0.348 0.4588 1.47 0.659 3.27 PRS_PLINK_0.001 674 Other complications of the puerperium NEC Female 62 669 12 pregnancy complications royalblue4 669, 62 168, 9 167, 19 167, 12 167, 22 0.245 0.136 0.0726 1.139 1.28 0.978 1.67 0.707 0.4 0.0773 1.112 2.03 0.925 4.44 0.266 0.433 0.539 0.2681 1.3 0.558 3.05 0.795 0.393 0.0433 1.364 2.21 1.02 4.78 PRS_PLINK_0.001 676 Other disorders of the breast associated with childbirth and disorders of lactation Female 12 150 12 pregnancy complications royalblue4 150, 12 38, 5 37, 1 37, 3 38, 3 -0.209 0.32 0.515 0.2884 0.812 0.433 1.52 -1.29 0.902 0.154 0.8123 0.277 0.0472 1.62 -0.653 0.728 0.369 0.4326 0.52 0.125 2.17 -0.392 0.769 0.61 0.2145 0.676 0.15 3.05 PRS_PLINK_0.001 679 Complications of in utero procedures Female 11 149 13 dermatologic firebrick 149, 11 38, 2 37, 4 37, 3 37, 2 0.0334 0.306 0.913 0.03947 1.03 0.568 1.88 1.35 0.972 0.165 0.782 3.85 0.574 25.9 0.356 0.839 0.672 0.1728 1.43 0.275 7.4 0.374 0.968 0.699 0.1555 1.45 0.218 9.68 PRS_PLINK_0.001 681 Superficial cellulitis and abscess Both 1193 18300 13 dermatologic firebrick 18300, 1193 4574, 294 4575, 289 4575, 302 4575, 308 0.000973 0.0298 0.974 0.01147 1 0.944 1.06 -0.0187 0.0853 0.827 0.08261 0.982 0.83 1.16 0.0204 0.0846 0.809 0.09187 1.02 0.865 1.2 0.046 0.0845 0.586 0.2317 1.05 0.887 1.24 PRS_PLINK_0.001 681.1 Cellulitis and abscess of fingers/toes Both 99 1435 13 dermatologic firebrick 1435, 99 359, 24 359, 23 358, 27 359, 25 0.0255 0.098 0.795 0.09961 1.03 0.846 1.24 -0.0201 0.293 0.945 0.02443 0.98 0.552 1.74 0.134 0.283 0.636 0.1966 1.14 0.656 1.99 0.0418 0.288 0.884 0.05331 1.04 0.593 1.83 PRS_PLINK_0.001 681.2 Cellulitis and abscess of face/neck Both 118 1315 13 dermatologic firebrick 1315, 118 329, 31 329, 24 328, 32 329, 31 0.0202 0.0975 0.836 0.07784 1.02 0.843 1.24 -0.251 0.277 0.366 0.4362 0.778 0.452 1.34 0.0233 0.26 0.929 0.03216 1.02 0.615 1.7 0.00804 0.261 0.975 0.01078 1.01 0.604 1.68 PRS_PLINK_0.001 681.3 Cellulitis and abscess of arm/hand Both 864 13866 13 dermatologic firebrick 13866, 864 3466, 211 3466, 214 3466, 212 3467, 227 -0.0045 0.0347 0.897 0.04725 0.996 0.93 1.07 0.0137 0.0997 0.891 0.05029 1.01 0.834 1.23 0.00276 0.1 0.978 0.009664 1 0.824 1.22 0.0696 0.0988 0.482 0.3173 1.07 0.883 1.3 PRS_PLINK_0.001 681.5 Cellulitis and abscess of leg, except foot Both 866 13851 13 dermatologic firebrick 13851, 866 3462, 208 3463, 219 3462, 213 3463, 226 -0.00567 0.0346 0.87 0.06047 0.994 0.929 1.06 0.0501 0.0995 0.615 0.2114 1.05 0.865 1.28 0.0203 0.1 0.839 0.0761 1.02 0.838 1.24 0.0788 0.0993 0.428 0.3689 1.08 0.891 1.31 PRS_PLINK_0.001 681.6 Cellulitis and abscess of foot, toe Both 859 13751 13 dermatologic firebrick 13751, 859 3437, 205 3438, 218 3437, 212 3438, 224 -0.00722 0.0348 0.836 0.07797 0.993 0.927 1.06 0.0595 0.0999 0.551 0.2586 1.06 0.873 1.29 0.0303 0.101 0.764 0.117 1.03 0.846 1.26 0.0845 0.0999 0.398 0.4006 1.09 0.895 1.32 PRS_PLINK_0.001 681.7 Cellulitis and abscess of trunk Both 93 1475 13 dermatologic firebrick 1475, 93 369, 18 369, 23 368, 25 369, 27 0.039 0.108 0.719 0.1433 1.04 0.841 1.29 0.271 0.315 0.39 0.4091 1.31 0.707 2.43 0.349 0.308 0.257 0.59 1.42 0.775 2.59 0.456 0.306 0.136 0.867 1.58 0.867 2.87 PRS_PLINK_0.001 686 Other local infections of skin and subcutaneous tissue Both 230 3364 13 dermatologic firebrick 3364, 230 841, 60 841, 59 841, 61 841, 50 -0.0775 0.0681 0.256 0.5924 0.925 0.81 1.06 -0.0131 0.189 0.945 0.02467 0.987 0.682 1.43 0.0156 0.188 0.934 0.02975 1.02 0.703 1.47 -0.189 0.197 0.337 0.4724 0.828 0.563 1.22 PRS_PLINK_0.001 686.1 Carbuncle and furuncle Both 412 5929 13 dermatologic firebrick 5929, 412 1483, 96 1482, 104 1482, 107 1482, 105 0.0141 0.0509 0.782 0.1069 1.01 0.918 1.12 0.0687 0.145 0.636 0.1964 1.07 0.806 1.42 0.112 0.145 0.44 0.3563 1.12 0.842 1.48 0.0761 0.146 0.601 0.221 1.08 0.811 1.44 PRS_PLINK_0.001 686.3 Pilonidal cyst Both 103 1456 13 dermatologic firebrick 1456, 103 364, 23 364, 16 364, 30 364, 34 0.155 0.0996 0.12 0.9194 1.17 0.96 1.42 -0.328 0.321 0.307 0.5131 0.721 0.385 1.35 0.268 0.28 0.337 0.472 1.31 0.756 2.26 0.364 0.274 0.185 0.7329 1.44 0.84 2.46 PRS_PLINK_0.001 686.4 Pyogenic granuloma Both 87 949 13 dermatologic firebrick 949, 87 238, 19 237, 25 237, 20 237, 23 0.0712 0.112 0.524 0.2807 1.07 0.863 1.34 0.289 0.314 0.358 0.4465 1.34 0.721 2.47 0.0715 0.322 0.824 0.0841 1.07 0.572 2.02 0.11 0.319 0.731 0.136 1.12 0.597 2.08 PRS_PLINK_0.001 687 Symptoms affecting skin Both 109 1434 13 dermatologic firebrick 1434, 109 359, 21 358, 34 358, 30 359, 24 0.0212 0.0971 0.827 0.08231 1.02 0.844 1.24 0.496 0.28 0.077 1.114 1.64 0.948 2.84 0.319 0.288 0.268 0.5718 1.38 0.782 2.42 0.126 0.299 0.674 0.1715 1.13 0.631 2.04 PRS_PLINK_0.001 687.1 Rash and other nonspecific skin eruption Both 364 5491 13 dermatologic firebrick 5491, 364 1373, 109 1373, 92 1372, 80 1373, 83 -0.114 0.0541 0.0347 1.46 0.892 0.802 0.992 -0.162 0.146 0.266 0.575 0.85 0.639 1.13 -0.309 0.151 0.0411 1.386 0.734 0.546 0.988 -0.284 0.15 0.059 1.229 0.753 0.561 1.01 PRS_PLINK_0.001 687.2 Localized superficial swelling, mass, or lump Both 65 720 13 dermatologic firebrick 720, 65 180, 17 180, 15 180, 19 180, 14 -0.0458 0.126 0.716 0.1449 0.955 0.746 1.22 -0.174 0.359 0.628 0.202 0.84 0.416 1.7 0.119 0.342 0.728 0.1376 1.13 0.576 2.2 -0.148 0.366 0.686 0.1634 0.863 0.421 1.77 PRS_PLINK_0.001 687.3 Changes in skin texture Both 22 281 13 dermatologic firebrick 281, 22 71, 6 70, 7 70, 4 70, 5 -0.0864 0.216 0.689 0.1618 0.917 0.601 1.4 0.275 0.57 0.629 0.2012 1.32 0.431 4.03 -0.701 0.658 0.287 0.542 0.496 0.137 1.8 -0.00837 0.599 0.989 0.004872 0.992 0.307 3.21 PRS_PLINK_0.001 687.4 Disturbance of skin sensation Both 473 7543 13 dermatologic firebrick 7543, 473 1886, 111 1886, 109 1885, 125 1886, 128 0.0394 0.0471 0.403 0.3951 1.04 0.949 1.14 -0.0196 0.138 0.887 0.05188 0.981 0.748 1.29 0.126 0.134 0.347 0.4599 1.13 0.872 1.48 0.126 0.134 0.346 0.4609 1.13 0.873 1.47 PRS_PLINK_0.001 689 Disorder of skin and subcutaneous tissue NOS Both 1313 14415 13 dermatologic firebrick 14415, 1313 3603, 338 3604, 325 3603, 319 3604, 331 -0.0234 0.0289 0.42 0.3771 0.977 0.923 1.03 -0.0366 0.0811 0.652 0.186 0.964 0.822 1.13 -0.0587 0.0816 0.472 0.3259 0.943 0.804 1.11 -0.0232 0.0812 0.775 0.1108 0.977 0.833 1.15 PRS_PLINK_0.001 690 Erythematosquamous dermatosis Both 12 188 13 dermatologic firebrick 188, 12 47, 3 47, 2 47, 5 47, 2 0.047 0.306 0.878 0.05643 1.05 0.575 1.91 -0.143 0.735 0.846 0.07268 0.867 0.205 3.66 0.311 0.683 0.649 0.188 1.37 0.358 5.21 -0.125 0.758 0.87 0.06071 0.883 0.2 3.9 PRS_PLINK_0.001 690.1 Seborrheic dermatitis Both 9 141 13 dermatologic firebrick 141, 9 36, 2 35, 2 35, 4 35, 1 -0.0984 0.328 0.764 0.1169 0.906 0.477 1.72 -0.0329 0.831 0.968 0.01392 0.968 0.19 4.93 0.205 0.839 0.807 0.09324 1.23 0.237 6.36 -0.522 0.869 0.548 0.2611 0.593 0.108 3.26 PRS_PLINK_0.001 691 Congenital anomalies of skin Both 30 304 13 dermatologic firebrick 304, 30 76, 4 76, 11 76, 7 76, 8 0.0811 0.17 0.634 0.198 1.08 0.777 1.51 0.921 0.553 0.096 1.018 2.51 0.849 7.43 0.451 0.575 0.432 0.364 1.57 0.509 4.85 0.564 0.564 0.317 0.4984 1.76 0.582 5.31 PRS_PLINK_0.001 694 Dyschromia and Vitiligo Both 242 2475 13 dermatologic firebrick 2475, 242 619, 60 619, 64 618, 56 619, 62 0.00896 0.0666 0.893 0.04913 1.01 0.885 1.15 0.0536 0.188 0.775 0.1106 1.06 0.73 1.52 -0.0409 0.193 0.833 0.07961 0.96 0.657 1.4 0.0473 0.189 0.803 0.0955 1.05 0.724 1.52 PRS_PLINK_0.001 694.1 Vitiligo Both 14 163 13 dermatologic firebrick 163, 14 41, 2 41, 6 40, 4 41, 2 -0.04 0.304 0.895 0.04812 0.961 0.53 1.74 0.848 0.767 0.269 0.5706 2.33 0.52 10.5 0.256 0.785 0.745 0.1281 1.29 0.277 6.02 0.0228 0.803 0.977 0.009943 1.02 0.212 4.94 PRS_PLINK_0.001 694.2 Other dyschromia Both 201 1984 13 dermatologic firebrick 1984, 201 496, 52 496, 48 496, 44 496, 57 0.0281 0.0722 0.697 0.1566 1.03 0.893 1.18 -0.101 0.209 0.629 0.2011 0.904 0.6 1.36 -0.147 0.213 0.491 0.3093 0.864 0.569 1.31 0.105 0.202 0.601 0.2208 1.11 0.748 1.65 PRS_PLINK_0.001 694.3 Vascular disorders of skin Both 21 282 13 dermatologic firebrick 282, 21 71, 3 70, 7 70, 4 71, 7 0.139 0.219 0.525 0.2796 1.15 0.748 1.77 0.951 0.637 0.135 0.8681 2.59 0.743 9.02 0.461 0.688 0.503 0.2985 1.59 0.412 6.1 0.634 0.63 0.314 0.5025 1.89 0.548 6.49 PRS_PLINK_0.001 695 Erythematous conditions Both 473 6023 13 dermatologic firebrick 6023, 473 1506, 119 1506, 121 1505, 123 1506, 110 -0.0254 0.0481 0.597 0.2241 0.975 0.887 1.07 0.0204 0.134 0.879 0.05623 1.02 0.785 1.33 0.025 0.134 0.852 0.06972 1.03 0.789 1.33 -0.0669 0.137 0.626 0.2037 0.935 0.715 1.22 PRS_PLINK_0.001 695.1 Toxic erythema Both 24 267 13 dermatologic firebrick 267, 24 67, 7 67, 8 66, 7 67, 2 -0.312 0.22 0.156 0.8069 0.732 0.475 1.13 0.159 0.534 0.766 0.116 1.17 0.412 3.34 0.069 0.537 0.898 0.04683 1.07 0.374 3.07 -1.29 0.716 0.0709 1.149 0.274 0.0674 1.12 PRS_PLINK_0.001 695.2 Bullous dermatoses Both 27 325 13 dermatologic firebrick 325, 27 82, 10 81, 5 81, 6 81, 6 -0.389 0.2 0.0514 1.289 0.677 0.458 1 -0.665 0.538 0.216 0.6648 0.514 0.179 1.48 -0.495 0.509 0.331 0.4805 0.609 0.225 1.65 -0.686 0.534 0.199 0.7019 0.504 0.177 1.43 PRS_PLINK_0.001 695.21 Dermatitis herpetiformis Both 12 139 13 dermatologic firebrick 139, 12 35, 3 35, 4 34, 2 35, 3 -0.257 0.304 0.398 0.3997 0.773 0.426 1.4 0.105 0.762 0.891 0.05027 1.11 0.249 4.95 0.002 0.874 0.998 0.0007953 1 0.181 5.55 0.2 0.78 0.797 0.09836 1.22 0.265 5.64 PRS_PLINK_0.001 695.22 Pemphigus and pemphigoid Both 16 175 13 dermatologic firebrick 175, 16 44, 7 44, 1 43, 4 44, 4 -0.299 0.236 0.204 0.6901 0.741 0.467 1.18 -1.54 0.878 0.0789 1.103 0.214 0.0383 1.19 -0.66 0.639 0.302 0.5198 0.517 0.148 1.81 -0.554 0.646 0.392 0.4072 0.575 0.162 2.04 PRS_PLINK_0.001 695.3 Rosacea Both 72 734 13 dermatologic firebrick 734, 72 184, 16 183, 20 183, 18 184, 18 0.0359 0.121 0.767 0.1152 1.04 0.818 1.31 0.187 0.343 0.586 0.2323 1.21 0.615 2.36 0.0531 0.35 0.88 0.05575 1.05 0.531 2.1 0.0845 0.35 0.809 0.09203 1.09 0.548 2.16 PRS_PLINK_0.001 695.4 Lupus (localized and systemic) Both 74 1041 13 dermatologic firebrick 1041, 74 261, 19 260, 19 260, 20 260, 16 -0.0501 0.118 0.672 0.1723 0.951 0.754 1.2 0.00593 0.326 0.985 0.006348 1.01 0.531 1.91 0.0578 0.32 0.857 0.06709 1.06 0.565 1.99 -0.13 0.337 0.699 0.1556 0.878 0.454 1.7 PRS_PLINK_0.001 695.41 Cutaneous lupus erythematosus Both 15 316 13 dermatologic firebrick 316, 15 79, 6 79, 1 79, 3 79, 5 0.0162 0.242 0.947 0.02385 1.02 0.632 1.63 -1.41 0.808 0.08 1.097 0.243 0.0498 1.18 -0.534 0.626 0.393 0.4051 0.586 0.172 2 -0.306 0.608 0.614 0.2115 0.736 0.224 2.42 PRS_PLINK_0.001 695.42 Systemic lupus erythematosus Both 68 869 13 dermatologic firebrick 869, 68 218, 20 217, 16 217, 18 217, 14 -0.139 0.127 0.273 0.564 0.87 0.678 1.12 -0.19 0.336 0.572 0.2424 0.827 0.428 1.6 -0.103 0.327 0.754 0.1228 0.903 0.476 1.71 -0.296 0.347 0.392 0.4062 0.743 0.377 1.47 PRS_PLINK_0.001 695.7 Prurigo and Lichen Both 176 2011 13 dermatologic firebrick 2011, 176 503, 50 503, 40 502, 45 503, 41 -0.028 0.0792 0.723 0.1407 0.972 0.833 1.14 -0.213 0.219 0.331 0.4798 0.808 0.526 1.24 -0.124 0.213 0.561 0.2512 0.883 0.582 1.34 -0.164 0.218 0.451 0.3458 0.849 0.554 1.3 PRS_PLINK_0.001 695.8 Other specified erythematous conditions Both 47 608 13 dermatologic firebrick 608, 47 152, 9 152, 14 152, 10 152, 14 0.136 0.156 0.386 0.4139 1.15 0.843 1.56 0.31 0.425 0.465 0.3326 1.36 0.593 3.14 0.0667 0.446 0.881 0.05496 1.07 0.446 2.56 0.445 0.424 0.294 0.5313 1.56 0.68 3.58 PRS_PLINK_0.001 695.81 Erythema nodosum Both 19 208 13 dermatologic firebrick 208, 19 52, 3 52, 4 52, 7 52, 5 0.0927 0.242 0.701 0.1541 1.1 0.683 1.76 0.064 0.677 0.925 0.03398 1.07 0.283 4.02 0.683 0.641 0.286 0.5434 1.98 0.564 6.95 0.222 0.666 0.739 0.1313 1.25 0.338 4.61 PRS_PLINK_0.001 695.9 Unspecified erythematous condition Both 61 1154 13 dermatologic firebrick 1154, 61 289, 15 288, 15 288, 16 289, 15 0.0162 0.13 0.901 0.04531 1.02 0.788 1.31 -0.0397 0.357 0.911 0.04033 0.961 0.478 1.93 0.0213 0.352 0.952 0.02149 1.02 0.512 2.04 0.0423 0.358 0.906 0.04281 1.04 0.517 2.11 PRS_PLINK_0.001 696 Psoriasis and related disorders Both 385 5658 13 dermatologic firebrick 5658, 385 1415, 95 1414, 98 1414, 99 1415, 93 0.034 0.053 0.522 0.2827 1.03 0.932 1.15 0.0432 0.148 0.77 0.1132 1.04 0.781 1.4 0.0586 0.148 0.692 0.1601 1.06 0.794 1.42 -0.0156 0.15 0.917 0.03751 0.985 0.733 1.32 PRS_PLINK_0.001 696.4 Psoriasis Both 371 5537 13 dermatologic firebrick 5537, 371 1385, 92 1384, 95 1384, 95 1384, 89 0.0327 0.0541 0.546 0.2631 1.03 0.929 1.15 0.0447 0.15 0.766 0.1156 1.05 0.779 1.4 0.0484 0.151 0.748 0.1263 1.05 0.781 1.41 -0.0336 0.153 0.826 0.083 0.967 0.716 1.31 PRS_PLINK_0.001 696.41 Psoriasis vulgaris Both 269 4216 13 dermatologic firebrick 4216, 269 1054, 61 1054, 76 1054, 70 1054, 62 0.0158 0.0631 0.802 0.09563 1.02 0.898 1.15 0.25 0.176 0.156 0.8057 1.28 0.909 1.81 0.147 0.179 0.413 0.3844 1.16 0.815 1.65 0.0162 0.184 0.93 0.03148 1.02 0.708 1.46 PRS_PLINK_0.001 696.42 Psoriatic arthropathy Both 119 1890 13 dermatologic firebrick 1890, 119 473, 33 472, 29 472, 27 473, 30 0.0286 0.0963 0.767 0.1154 1.03 0.852 1.24 -0.117 0.257 0.649 0.188 0.889 0.537 1.47 -0.191 0.262 0.466 0.3317 0.826 0.495 1.38 -0.0889 0.255 0.727 0.1383 0.915 0.555 1.51 PRS_PLINK_0.001 697 Sarcoidosis Both 114 1418 13 dermatologic firebrick 1418, 114 355, 30 354, 26 354, 32 355, 26 -0.0406 0.0987 0.681 0.167 0.96 0.791 1.17 -0.183 0.273 0.504 0.2978 0.833 0.488 1.42 0.0122 0.263 0.963 0.0164 1.01 0.604 1.7 -0.179 0.276 0.518 0.2861 0.836 0.487 1.44 PRS_PLINK_0.001 698 Pruritus and related conditions Both 155 1991 13 dermatologic firebrick 1991, 155 498, 39 498, 34 497, 39 498, 43 0.0752 0.0836 0.368 0.4338 1.08 0.915 1.27 -0.132 0.238 0.58 0.2366 0.877 0.55 1.4 -0.00191 0.231 0.993 0.002872 0.998 0.634 1.57 0.139 0.228 0.54 0.2673 1.15 0.736 1.8 PRS_PLINK_0.001 700 Corns and callosities Both 51 695 13 dermatologic firebrick 695, 51 174, 10 174, 9 173, 19 174, 13 0.0941 0.143 0.51 0.2926 1.1 0.831 1.45 -0.0101 0.442 0.982 0.00798 0.99 0.416 2.35 0.641 0.39 0.1 0.9985 1.9 0.884 4.07 0.363 0.416 0.383 0.4163 1.44 0.636 3.25 PRS_PLINK_0.001 701 Other hypertrophic and atrophic conditions of skin Both 1030 11941 13 dermatologic firebrick 11941, 1030 2986, 242 2985, 275 2985, 239 2985, 274 0.0489 0.0331 0.139 0.8557 1.05 0.984 1.12 0.126 0.0917 0.17 0.7707 1.13 0.948 1.36 -0.00902 0.0948 0.924 0.03421 0.991 0.823 1.19 0.119 0.0921 0.196 0.7086 1.13 0.941 1.35 PRS_PLINK_0.001 701.1 Keratoderma, acquired Both 16 219 13 dermatologic firebrick 219, 16 55, 3 55, 5 54, 7 55, 1 -0.00338 0.238 0.989 0.004961 0.997 0.626 1.59 -0.214 0.733 0.77 0.1133 0.807 0.192 3.4 0.947 0.663 0.153 0.8154 2.58 0.703 9.45 -0.678 0.858 0.429 0.3673 0.507 0.0944 2.73 PRS_PLINK_0.001 701.2 Scar conditions and fibrosis of skin Both 515 5983 13 dermatologic firebrick 5983, 515 1496, 122 1496, 146 1495, 113 1496, 134 0.0255 0.0465 0.583 0.2344 1.03 0.937 1.12 0.176 0.127 0.168 0.7737 1.19 0.928 1.53 -0.0661 0.135 0.625 0.2043 0.936 0.718 1.22 0.0799 0.13 0.54 0.2674 1.08 0.839 1.4 PRS_PLINK_0.001 701.3 Circumscribed scleroderma Both 11 143 13 dermatologic firebrick 143, 11 36, 3 36, 2 35, 1 36, 5 0.201 0.335 0.548 0.2612 1.22 0.634 2.36 -1.98 1.65 0.229 0.6395 0.138 0.00546 3.49 -2.56 1.43 0.0747 1.127 0.0777 0.00468 1.29 0.229 0.723 0.752 0.1239 1.26 0.305 5.19 PRS_PLINK_0.001 701.4 Keloid scar Both 42 593 13 dermatologic firebrick 593, 42 149, 11 148, 12 148, 9 148, 10 -0.0326 0.162 0.84 0.07558 0.968 0.705 1.33 -0.0102 0.42 0.981 0.008461 0.99 0.435 2.25 -0.275 0.435 0.528 0.2773 0.76 0.324 1.78 -0.0425 0.429 0.921 0.03577 0.958 0.414 2.22 PRS_PLINK_0.001 701.5 Abnormal granulation tissue Both 98 1223 13 dermatologic firebrick 1223, 98 306, 26 306, 23 305, 24 306, 25 0.0127 0.105 0.904 0.04394 1.01 0.824 1.24 -0.188 0.294 0.523 0.2812 0.829 0.466 1.48 -0.157 0.292 0.59 0.2294 0.854 0.482 1.51 -0.0698 0.289 0.809 0.09218 0.933 0.53 1.64 PRS_PLINK_0.001 701.6 Acquired acanthosis nigricans Both 29 223 13 dermatologic firebrick 223, 29 56, 7 56, 7 55, 10 56, 5 -0.114 0.199 0.567 0.2462 0.893 0.605 1.32 0.00241 0.565 0.997 0.001481 1 0.331 3.03 0.38 0.536 0.478 0.321 1.46 0.512 4.18 -0.266 0.567 0.639 0.1945 0.766 0.252 2.33 PRS_PLINK_0.001 702 Degenerative skin conditions and other dermatoses Both 1340 13590 13 dermatologic firebrick 13590, 1340 3398, 326 3397, 340 3397, 324 3398, 350 0.01 0.0288 0.728 0.1381 1.01 0.955 1.07 0.035 0.0812 0.666 0.1766 1.04 0.883 1.21 -0.0089 0.0822 0.914 0.03917 0.991 0.844 1.16 0.0576 0.081 0.478 0.3209 1.06 0.904 1.24 PRS_PLINK_0.001 702.1 Actinic keratosis Both 607 6368 13 dermatologic firebrick 6368, 607 1592, 153 1592, 153 1592, 151 1592, 150 -0.0162 0.0424 0.703 0.1531 0.984 0.905 1.07 -0.0158 0.119 0.895 0.0484 0.984 0.779 1.24 -0.0141 0.12 0.907 0.0425 0.986 0.779 1.25 -0.0183 0.12 0.879 0.05601 0.982 0.775 1.24 PRS_PLINK_0.001 702.2 Seborrheic keratosis Both 766 7624 13 dermatologic firebrick 7624, 766 1906, 180 1906, 195 1906, 182 1906, 209 0.0433 0.038 0.254 0.5948 1.04 0.969 1.12 0.076 0.108 0.481 0.3175 1.08 0.873 1.33 0.00811 0.11 0.941 0.02635 1.01 0.813 1.25 0.13 0.107 0.226 0.6465 1.14 0.923 1.4 PRS_PLINK_0.001 703 Diseases of nail, NOS Both 70 884 13 dermatologic firebrick 884, 70 221, 18 221, 24 221, 14 221, 14 -0.113 0.121 0.35 0.456 0.893 0.705 1.13 0.342 0.324 0.291 0.5365 1.41 0.746 2.66 -0.217 0.361 0.549 0.2605 0.805 0.397 1.64 -0.222 0.356 0.533 0.2731 0.801 0.399 1.61 PRS_PLINK_0.001 703.1 Ingrowing nail Both 150 2476 13 dermatologic firebrick 2476, 150 618, 36 619, 52 619, 34 619, 28 -0.0487 0.0812 0.548 0.2611 0.952 0.812 1.12 0.377 0.221 0.0879 1.056 1.46 0.946 2.25 -0.0269 0.242 0.911 0.04028 0.973 0.606 1.56 -0.225 0.254 0.376 0.4245 0.799 0.485 1.31 PRS_PLINK_0.001 704 Diseases of hair and hair follicles Both 1188 13572 13 dermatologic firebrick 13572, 1188 3393, 275 3393, 294 3393, 315 3393, 304 0.0397 0.0302 0.188 0.7256 1.04 0.981 1.1 0.0621 0.0872 0.477 0.3217 1.06 0.897 1.26 0.141 0.0861 0.101 0.9967 1.15 0.973 1.36 0.103 0.087 0.237 0.6259 1.11 0.935 1.31 PRS_PLINK_0.001 704.1 Alopecia Both 26 313 13 dermatologic firebrick 313, 26 79, 8 78, 10 78, 5 78, 3 -0.255 0.206 0.215 0.6684 0.775 0.518 1.16 0.236 0.486 0.628 0.2022 1.27 0.488 3.28 -0.772 0.585 0.187 0.728 0.462 0.147 1.45 -0.841 0.626 0.179 0.7464 0.431 0.127 1.47 PRS_PLINK_0.001 704.8 Other specified diseases of hair and hair follicles Both 22 198 13 dermatologic firebrick 198, 22 50, 6 49, 5 49, 6 50, 5 -0.176 0.209 0.4 0.3984 0.839 0.557 1.26 PRS_PLINK_0.001 705 Disorders of sweat glands Both 40 595 13 dermatologic firebrick 595, 40 149, 9 149, 10 148, 9 149, 12 0.106 0.162 0.512 0.291 1.11 0.81 1.53 0.177 0.45 0.694 0.1584 1.19 0.494 2.88 0.0123 0.451 0.978 0.009522 1.01 0.419 2.45 0.45 0.443 0.311 0.5079 1.57 0.657 3.74 PRS_PLINK_0.001 705.3 Hidradenitis Both 32 486 13 dermatologic firebrick 486, 32 122, 7 121, 8 121, 7 122, 10 0.0321 0.179 0.858 0.06676 1.03 0.728 1.47 0.186 0.488 0.703 0.1531 1.2 0.463 3.13 0.071 0.506 0.888 0.05143 1.07 0.399 2.89 0.373 0.474 0.431 0.3656 1.45 0.574 3.67 PRS_PLINK_0.001 705.8 Hyperhidrosis Both 102 1520 13 dermatologic firebrick 1520, 102 380, 30 380, 25 380, 27 380, 20 -0.124 0.0981 0.205 0.6876 0.883 0.729 1.07 -0.115 0.274 0.674 0.1713 0.891 0.521 1.52 -0.0389 0.273 0.887 0.05218 0.962 0.563 1.64 -0.374 0.29 0.197 0.7052 0.688 0.389 1.21 PRS_PLINK_0.001 706 Diseases of sebaceous glands Both 1853 21297 13 dermatologic firebrick 21297, 1853 5324, 422 5324, 467 5324, 479 5324, 485 0.0544 0.0243 0.0254 1.595 1.06 1.01 1.11 0.103 0.0699 0.141 0.8511 1.11 0.967 1.27 0.13 0.0696 0.0618 1.209 1.14 0.994 1.31 0.138 0.0696 0.0476 1.323 1.15 1 1.32 PRS_PLINK_0.001 706.1 Acne Both 13 197 13 dermatologic firebrick 197, 13 50, 2 49, 6 49, 2 49, 3 -0.177 0.244 0.468 0.3297 0.838 0.519 1.35 1.37 0.822 0.0946 1.024 3.95 0.789 19.8 0.22 0.822 0.789 0.1031 1.25 0.249 6.25 0.0822 0.817 0.92 0.03629 1.09 0.219 5.39 PRS_PLINK_0.001 706.2 Sebaceous cyst Both 1951 22241 13 dermatologic firebrick 22241, 1951 5560, 449 5560, 489 5560, 504 5560, 509 0.0548 0.0236 0.0203 1.693 1.06 1.01 1.11 0.0867 0.068 0.202 0.6939 1.09 0.954 1.25 0.121 0.0677 0.0732 1.136 1.13 0.989 1.29 0.127 0.0677 0.06 1.222 1.14 0.995 1.3 PRS_PLINK_0.001 707 Chronic ulcer of skin Both 136 4786 13 dermatologic firebrick 4786, 136 1197, 36 1196, 43 1196, 38 1197, 19 -0.231 0.0834 0.0056 2.252 0.794 0.674 0.935 0.164 0.225 0.467 0.331 1.18 0.758 1.83 0.0463 0.231 0.841 0.07521 1.05 0.666 1.65 -0.678 0.279 0.015 1.824 0.507 0.294 0.877 PRS_PLINK_0.001 707.1 Decubitus ulcer Both 37 2160 13 dermatologic firebrick 2160, 37 540, 11 540, 10 540, 13 540, 3 -0.29 0.155 0.0616 1.211 0.748 0.552 1.01 -0.0941 0.406 0.817 0.08787 0.91 0.41 2.02 0.204 0.385 0.597 0.2241 1.23 0.576 2.61 -1.17 0.564 0.0376 1.425 0.31 0.103 0.935 PRS_PLINK_0.001 709 Diffuse diseases of connective tissue Both 744 8736 13 dermatologic firebrick 8736, 744 2184, 184 2184, 182 2184, 183 2184, 195 0.000926 0.0383 0.981 0.008466 1 0.929 1.08 -0.00448 0.109 0.967 0.01454 0.996 0.805 1.23 0.00393 0.109 0.971 0.01268 1 0.811 1.24 0.047 0.107 0.662 0.1792 1.05 0.849 1.29 PRS_PLINK_0.001 709.2 Sicca syndrome Both 104 1309 13 dermatologic firebrick 1309, 104 328, 27 327, 24 327, 20 327, 33 0.0109 0.102 0.915 0.03844 1.01 0.827 1.24 -0.0927 0.284 0.744 0.1285 0.911 0.523 1.59 -0.276 0.298 0.355 0.4495 0.759 0.423 1.36 0.206 0.273 0.45 0.3466 1.23 0.72 2.1 PRS_PLINK_0.001 709.3 Systemic sclerosis Both 32 454 13 dermatologic firebrick 454, 32 114, 6 113, 5 113, 10 114, 11 0.133 0.174 0.445 0.3517 1.14 0.812 1.61 -0.139 0.558 0.804 0.09472 0.871 0.291 2.6 0.566 0.516 0.273 0.5645 1.76 0.641 4.84 0.296 0.502 0.556 0.2549 1.34 0.502 3.6 PRS_PLINK_0.001 709.6 Other specified diffuse diseases of connective tissue Both 11 162 13 dermatologic firebrick 162, 11 41, 1 40, 2 40, 3 41, 5 0.301 0.314 0.337 0.4718 1.35 0.73 2.5 -0.422 1.17 0.719 0.1433 0.655 0.0656 6.54 0.894 0.886 0.313 0.5039 2.44 0.43 13.9 1.39 0.857 0.105 0.9774 4.01 0.747 21.5 PRS_PLINK_0.001 709.7 Unspecified diffuse connective tissue disease Both 603 6920 13 dermatologic firebrick 6920, 603 1730, 153 1730, 147 1730, 152 1730, 151 -0.0134 0.0426 0.754 0.1227 0.987 0.908 1.07 -0.0339 0.12 0.778 0.1091 0.967 0.764 1.22 -0.00134 0.119 0.991 0.0039 0.999 0.79 1.26 -0.0231 0.12 0.847 0.07196 0.977 0.773 1.24 PRS_PLINK_0.001 710 Osteomyelitis, periostitis, and other infections involving bone Both 100 1587 14 musculoskeletal darkolivegreen 1587, 100 397, 21 397, 27 396, 24 397, 28 0.0488 0.097 0.615 0.211 1.05 0.868 1.27 0.243 0.289 0.4 0.3975 1.28 0.723 2.25 0.18 0.297 0.546 0.2627 1.2 0.668 2.14 0.246 0.289 0.395 0.4036 1.28 0.725 2.26 PRS_PLINK_0.001 710.1 Osteomyelitis Both 89 1483 14 musculoskeletal darkolivegreen 1483, 89 371, 20 371, 23 370, 23 371, 23 0.004 0.102 0.969 0.01382 1 0.822 1.23 0.136 0.303 0.652 0.1854 1.15 0.633 2.07 0.178 0.304 0.56 0.2521 1.19 0.658 2.17 0.0554 0.306 0.857 0.06724 1.06 0.58 1.93 PRS_PLINK_0.001 710.12 Chronic osteomyelitis Both 35 482 14 musculoskeletal darkolivegreen 482, 35 121, 7 120, 11 120, 9 121, 8 -0.0617 0.163 0.706 0.1514 0.94 0.682 1.3 0.504 0.476 0.29 0.5378 1.65 0.651 4.21 0.267 0.488 0.585 0.233 1.31 0.502 3.4 0.00176 0.502 0.997 0.001213 1 0.374 2.68 PRS_PLINK_0.001 710.19 Unspecified osteomyelitis Both 59 1091 14 musculoskeletal darkolivegreen 1091, 59 273, 12 273, 12 272, 20 273, 15 0.106 0.127 0.401 0.3968 1.11 0.868 1.43 -0.00648 0.391 0.987 0.005784 0.994 0.462 2.14 0.561 0.366 0.125 0.9026 1.75 0.856 3.59 0.0744 0.381 0.845 0.07304 1.08 0.51 2.27 PRS_PLINK_0.001 711 Arthropathy associated with infections Both 62 1159 14 musculoskeletal darkolivegreen 1159, 62 290, 14 290, 15 289, 18 290, 15 0.0268 0.125 0.831 0.08035 1.03 0.803 1.31 0.0423 0.365 0.908 0.04195 1.04 0.51 2.13 0.23 0.353 0.516 0.2878 1.26 0.63 2.51 0.071 0.362 0.845 0.07337 1.07 0.528 2.18 PRS_PLINK_0.001 711.1 Pyogenic arthritis Both 46 894 14 musculoskeletal darkolivegreen 894, 46 224, 12 223, 10 223, 10 224, 14 0.042 0.144 0.771 0.1132 1.04 0.787 1.38 -0.145 0.412 0.725 0.1399 0.865 0.385 1.94 -0.0665 0.414 0.872 0.05927 0.936 0.415 2.11 0.154 0.386 0.689 0.1618 1.17 0.548 2.49 PRS_PLINK_0.001 712 Infective connective tissue disorders Both 15 216 14 musculoskeletal darkolivegreen 216, 15 54, 2 54, 3 54, 4 54, 6 0.336 0.239 0.161 0.7935 1.4 0.875 2.24 0.17 0.745 0.819 0.08666 1.19 0.275 5.11 0.597 0.775 0.441 0.3552 1.82 0.397 8.31 0.973 0.739 0.188 0.7259 2.64 0.622 11.2 PRS_PLINK_0.001 713 Arthropathy associated with other disorders classified elsewhere Both 13 387 14 musculoskeletal darkolivegreen 387, 13 97, 2 97, 2 96, 7 97, 2 0.109 0.261 0.676 0.1699 1.12 0.669 1.86 -0.0957 0.8 0.905 0.04346 0.909 0.189 4.36 1.04 0.768 0.178 0.7508 2.82 0.625 12.7 0.0891 0.781 0.909 0.04135 1.09 0.236 5.05 PRS_PLINK_0.001 713.5 Arthropathy associated with neurological disorders Both 0 181 14 musculoskeletal darkolivegreen 181, 0 46 45 45 45 0.116 0.492 0.813 0.08966 1.12 0.428 2.95 -0.00608 1.1 0.996 0.001918 0.994 0.115 8.6 0.0921 1.07 0.931 0.03093 1.1 0.135 8.89 -0.0607 1.09 0.956 0.01967 0.941 0.11 8.02 PRS_PLINK_0.001 714 Rheumatoid arthritis and other inflammatory polyarthropathies Both 746 12478 14 musculoskeletal darkolivegreen 12478, 746 3120, 173 3119, 199 3119, 201 3120, 173 -0.0107 0.038 0.779 0.1085 0.989 0.918 1.07 0.141 0.107 0.186 0.7294 1.15 0.934 1.42 0.153 0.107 0.152 0.8169 1.17 0.945 1.44 0.000842 0.111 0.994 0.002645 1 0.806 1.24 PRS_PLINK_0.001 714.1 Rheumatoid arthritis Both 673 11266 14 musculoskeletal darkolivegreen 11266, 673 2817, 159 2816, 176 2816, 187 2817, 151 -0.0204 0.0398 0.608 0.2158 0.98 0.906 1.06 0.103 0.112 0.361 0.4421 1.11 0.889 1.38 0.166 0.111 0.135 0.8696 1.18 0.95 1.47 -0.0508 0.117 0.664 0.1779 0.951 0.756 1.2 PRS_PLINK_0.001 715 Other inflammatory spondylopathies Both 258 4304 14 musculoskeletal darkolivegreen 4304, 258 1076, 63 1076, 63 1076, 60 1076, 72 0.0274 0.0644 0.67 0.1736 1.03 0.906 1.17 -0.0049 0.181 0.978 0.009468 0.995 0.697 1.42 -0.0721 0.183 0.695 0.1583 0.93 0.649 1.33 0.12 0.177 0.495 0.305 1.13 0.798 1.59 PRS_PLINK_0.001 715.1 Sacroiliitis NEC Both 15 311 14 musculoskeletal darkolivegreen 311, 15 78, 5 78, 2 77, 6 78, 2 -0.155 0.242 0.521 0.2832 0.856 0.533 1.38 -0.718 0.696 0.302 0.5204 0.487 0.125 1.91 0.0971 0.574 0.866 0.06258 1.1 0.357 3.4 -0.831 0.686 0.226 0.6467 0.436 0.114 1.67 PRS_PLINK_0.001 715.2 Ankylosing spondylitis Both 120 1575 14 musculoskeletal darkolivegreen 1575, 120 394, 22 394, 32 393, 27 394, 39 0.126 0.0924 0.172 0.7645 1.13 0.947 1.36 0.331 0.279 0.236 0.6278 1.39 0.806 2.4 0.137 0.289 0.636 0.1969 1.15 0.651 2.02 0.513 0.27 0.0578 1.238 1.67 0.983 2.84 PRS_PLINK_0.001 716 Other arthropathies Both 6812 71088 14 musculoskeletal darkolivegreen 71088, 6812 17772, 1597 17772, 1679 17772, 1737 17772, 1798 0.0324 0.0128 0.0113 1.948 1.03 1.01 1.06 0.0416 0.0367 0.257 0.5898 1.04 0.97 1.12 0.064 0.0365 0.0793 1.101 1.07 0.993 1.15 0.0933 0.0363 0.0101 1.995 1.1 1.02 1.18 PRS_PLINK_0.001 716.1 Unspecified polyarthropathy or polyarthritis Both 587 9066 14 musculoskeletal darkolivegreen 9066, 587 2267, 127 2266, 159 2266, 151 2267, 150 0.0866 0.0427 0.0427 1.37 1.09 1 1.19 0.231 0.122 0.0588 1.231 1.26 0.991 1.6 0.164 0.124 0.188 0.725 1.18 0.923 1.5 0.17 0.125 0.172 0.7638 1.19 0.929 1.51 PRS_PLINK_0.001 716.2 Unspecified monoarthritis Both 2935 40438 14 musculoskeletal darkolivegreen 40438, 2935 10110, 707 10109, 733 10109, 757 10110, 738 0.0134 0.0192 0.484 0.3154 1.01 0.976 1.05 0.0377 0.0546 0.49 0.3102 1.04 0.933 1.16 0.0718 0.0543 0.186 0.7308 1.07 0.966 1.19 0.0477 0.0547 0.383 0.4173 1.05 0.942 1.17 PRS_PLINK_0.001 716.9 Arthropathy NOS Both 6514 70244 14 musculoskeletal darkolivegreen 70244, 6514 17561, 1545 17561, 1584 17561, 1659 17561, 1725 0.0289 0.0131 0.0269 1.571 1.03 1 1.06 0.0175 0.0374 0.639 0.1943 1.02 0.946 1.1 0.0533 0.0371 0.151 0.8208 1.05 0.981 1.13 0.0859 0.0369 0.0199 1.7 1.09 1.01 1.17 PRS_PLINK_0.001 717 Polymyalgia Rheumatica Both 231 2682 14 musculoskeletal darkolivegreen 2682, 231 671, 56 670, 56 670, 57 671, 62 0.0646 0.0676 0.339 0.4694 1.07 0.934 1.22 0.00349 0.195 0.986 0.006244 1 0.685 1.47 0.00127 0.194 0.995 0.002274 1 0.684 1.46 0.0668 0.192 0.728 0.1378 1.07 0.734 1.56 PRS_PLINK_0.001 720 Spinal stenosis Both 644 9271 14 musculoskeletal darkolivegreen 9271, 644 2318, 167 2318, 148 2317, 160 2318, 169 0.0199 0.0411 0.629 0.2015 1.02 0.941 1.11 -0.13 0.116 0.265 0.5771 0.878 0.699 1.1 -0.057 0.114 0.618 0.209 0.945 0.755 1.18 0.0136 0.114 0.905 0.04339 1.01 0.811 1.27 PRS_PLINK_0.001 721 Spondylosis and allied disorders Both 1261 19608 14 musculoskeletal darkolivegreen 19608, 1261 4902, 315 4902, 326 4902, 322 4902, 298 -0.00718 0.0292 0.805 0.09394 0.993 0.938 1.05 0.0371 0.0814 0.648 0.1881 1.04 0.885 1.22 0.0252 0.0818 0.758 0.1205 1.03 0.874 1.2 -0.0554 0.0836 0.508 0.2945 0.946 0.803 1.11 PRS_PLINK_0.001 721.1 Spondylosis without myelopathy Both 819 12490 14 musculoskeletal darkolivegreen 12490, 819 3123, 207 3122, 213 3122, 213 3123, 186 -0.0278 0.0363 0.444 0.3527 0.973 0.906 1.04 0.0351 0.101 0.727 0.1382 1.04 0.85 1.26 0.0379 0.101 0.707 0.1506 1.04 0.852 1.27 -0.0982 0.104 0.347 0.4598 0.906 0.739 1.11 PRS_PLINK_0.001 721.2 Spondylosis with myelopathy Both 31 528 14 musculoskeletal darkolivegreen 528, 31 132, 3 132, 11 132, 7 132, 10 0.246 0.176 0.161 0.7933 1.28 0.907 1.81 1.29 0.588 0.0285 1.544 3.62 1.14 11.5 0.868 0.623 0.163 0.7871 2.38 0.703 8.08 1.09 0.581 0.0609 1.215 2.97 0.951 9.27 PRS_PLINK_0.001 721.8 Other allied disorders of spine Both 57 846 14 musculoskeletal darkolivegreen 846, 57 212, 16 211, 13 211, 19 212, 9 -0.119 0.134 0.373 0.4284 0.887 0.682 1.15 -0.319 0.371 0.39 0.409 0.727 0.351 1.5 -0.00834 0.348 0.981 0.008385 0.992 0.501 1.96 -0.545 0.407 0.181 0.7431 0.58 0.261 1.29 PRS_PLINK_0.001 722 Intervertebral disc disorders Both 1726 23175 14 musculoskeletal darkolivegreen 23175, 1726 5794, 424 5794, 461 5793, 399 5794, 442 0.0109 0.0251 0.664 0.1778 1.01 0.962 1.06 0.0809 0.0698 0.246 0.6082 1.08 0.946 1.24 -0.0572 0.0723 0.429 0.368 0.944 0.82 1.09 0.0406 0.0708 0.566 0.247 1.04 0.907 1.2 PRS_PLINK_0.001 722.1 Displacement of intervertebral disc Both 91 1320 14 musculoskeletal darkolivegreen 1320, 91 330, 20 330, 26 330, 18 330, 27 0.125 0.105 0.234 0.6299 1.13 0.922 1.39 0.223 0.299 0.456 0.341 1.25 0.696 2.24 -0.137 0.324 0.672 0.1728 0.872 0.462 1.64 0.294 0.301 0.329 0.4824 1.34 0.744 2.42 PRS_PLINK_0.001 722.6 Degeneration of intervertebral disc Both 503 7313 14 musculoskeletal darkolivegreen 7313, 503 1829, 112 1828, 138 1828, 125 1828, 128 0.0405 0.0465 0.384 0.4155 1.04 0.951 1.14 0.201 0.131 0.125 0.9039 1.22 0.946 1.58 0.106 0.134 0.426 0.3703 1.11 0.856 1.45 0.127 0.133 0.34 0.4691 1.14 0.874 1.48 PRS_PLINK_0.001 722.8 Postlaminectomy syndrome Both 9 184 14 musculoskeletal darkolivegreen 184, 9 46, 4 46, 4 46, 0 46, 1 -0.528 0.307 0.0861 1.065 0.59 0.323 1.08 -0.0696 0.67 0.917 0.03751 0.933 0.251 3.47 -2.79 1.3 0.0326 1.487 0.0616 0.00478 0.794 -1.22 0.876 0.164 0.7855 0.295 0.0531 1.64 PRS_PLINK_0.001 722.9 Other and unspecified disc disorder Both 882 11262 14 musculoskeletal darkolivegreen 11262, 882 2816, 213 2815, 244 2815, 208 2816, 217 -7.84e-05 0.0353 0.998 0.000769 1 0.933 1.07 0.14 0.0975 0.151 0.82 1.15 0.95 1.39 -0.0107 0.101 0.915 0.03836 0.989 0.811 1.21 0.0277 0.1 0.783 0.1063 1.03 0.844 1.25 PRS_PLINK_0.001 723 Other disorders of cervical region Both 77 1272 14 musculoskeletal darkolivegreen 1272, 77 318, 11 318, 27 318, 23 318, 16 -0.016 0.118 0.892 0.04948 0.984 0.781 1.24 0.857 0.35 0.0144 1.842 2.36 1.19 4.68 0.685 0.359 0.0562 1.251 1.98 0.982 4.01 0.396 0.378 0.296 0.5287 1.49 0.707 3.12 PRS_PLINK_0.001 723.1 Torticollis Both 17 256 14 musculoskeletal darkolivegreen 256, 17 64, 2 64, 7 64, 3 64, 5 0.0763 0.224 0.733 0.1348 1.08 0.696 1.67 0.885 0.723 0.221 0.6555 2.42 0.587 10 0.343 0.752 0.648 0.1881 1.41 0.323 6.15 0.719 0.706 0.308 0.5111 2.05 0.515 8.18 PRS_PLINK_0.001 724 Other and unspecified disorders of back Both 363 5321 14 musculoskeletal darkolivegreen 5321, 363 1331, 99 1330, 91 1330, 92 1330, 81 -0.0804 0.0547 0.142 0.849 0.923 0.829 1.03 -0.0893 0.149 0.55 0.2598 0.915 0.682 1.23 -0.0741 0.149 0.619 0.2082 0.929 0.693 1.24 -0.174 0.154 0.26 0.5856 0.84 0.621 1.14 PRS_PLINK_0.001 724.1 Disorders of sacrum Both 78 1055 14 musculoskeletal darkolivegreen 1055, 78 264, 27 264, 17 263, 16 264, 18 -0.173 0.113 0.125 0.9021 0.841 0.674 1.05 -0.376 0.314 0.231 0.6368 0.687 0.371 1.27 -0.488 0.319 0.127 0.8973 0.614 0.328 1.15 -0.382 0.313 0.223 0.6518 0.682 0.369 1.26 PRS_PLINK_0.001 724.2 Disorders of coccyx Both 78 1063 14 musculoskeletal darkolivegreen 1063, 78 266, 27 266, 17 265, 16 266, 18 -0.16 0.113 0.159 0.7998 0.852 0.682 1.06 -0.367 0.314 0.243 0.6136 0.693 0.374 1.28 -0.508 0.318 0.111 0.9565 0.602 0.322 1.12 -0.362 0.313 0.248 0.6063 0.696 0.377 1.29 PRS_PLINK_0.001 724.8 Other symptoms referable to back Both 12 159 14 musculoskeletal darkolivegreen 159, 12 40, 4 40, 4 39, 4 40, 0 -0.534 0.308 0.0836 1.078 0.587 0.321 1.07 -0.309 0.689 0.654 0.1845 0.734 0.19 2.83 -0.227 0.714 0.75 0.1247 0.797 0.197 3.23 -3.05 1.44 0.0339 1.47 0.0473 0.00282 0.793 PRS_PLINK_0.001 724.9 Other unspecified back disorders Both 275 4164 14 musculoskeletal darkolivegreen 4164, 275 1041, 68 1041, 72 1041, 71 1041, 64 -0.0373 0.0631 0.554 0.2566 0.963 0.851 1.09 0.0527 0.173 0.761 0.1186 1.05 0.751 1.48 0.0528 0.174 0.761 0.1186 1.05 0.75 1.48 -0.0367 0.178 0.837 0.07734 0.964 0.68 1.37 PRS_PLINK_0.001 726 Peripheral enthesopathies and allied syndromes Both 3016 38060 14 musculoskeletal darkolivegreen 38060, 3016 9514, 727 9515, 755 9515, 739 9515, 795 0.0283 0.019 0.137 0.8631 1.03 0.991 1.07 0.034 0.0539 0.528 0.2773 1.03 0.931 1.15 0.0167 0.0543 0.758 0.1203 1.02 0.914 1.13 0.0843 0.0536 0.116 0.9373 1.09 0.98 1.21 PRS_PLINK_0.001 726.1 Enthesopathy Both 1987 24646 14 musculoskeletal darkolivegreen 24646, 1987 6161, 514 6161, 489 6161, 466 6162, 518 -0.0111 0.0235 0.636 0.1965 0.989 0.944 1.04 -0.0534 0.0657 0.416 0.3806 0.948 0.834 1.08 -0.0978 0.0666 0.142 0.8485 0.907 0.796 1.03 0.000984 0.065 0.988 0.005273 1 0.881 1.14 PRS_PLINK_0.001 726.2 Synoviopathy Both 78 917 14 musculoskeletal darkolivegreen 917, 78 230, 16 229, 17 229, 22 229, 23 0.153 0.118 0.195 0.7108 1.17 0.925 1.47 0.0402 0.348 0.908 0.04196 1.04 0.527 2.06 0.319 0.329 0.332 0.4784 1.38 0.722 2.62 0.34 0.33 0.303 0.5182 1.4 0.736 2.68 PRS_PLINK_0.001 726.3 Bursitis Both 158 2156 14 musculoskeletal darkolivegreen 2156, 158 539, 36 539, 42 539, 45 539, 35 0.0282 0.0841 0.737 0.1325 1.03 0.872 1.21 0.13 0.231 0.574 0.2411 1.14 0.724 1.79 0.225 0.227 0.323 0.4911 1.25 0.802 1.96 -0.0484 0.242 0.841 0.07503 0.953 0.593 1.53 PRS_PLINK_0.001 727 Other disorders of synovium, tendon, and bursa Both 1603 19040 14 musculoskeletal darkolivegreen 19040, 1603 4760, 397 4760, 403 4760, 390 4760, 413 0.0116 0.0262 0.658 0.1817 1.01 0.961 1.07 0.0155 0.0736 0.833 0.07921 1.02 0.879 1.17 -0.0142 0.0743 0.849 0.07118 0.986 0.852 1.14 0.0402 0.0734 0.584 0.2338 1.04 0.902 1.2 PRS_PLINK_0.001 727.1 Synovitis and tenosynovitis Both 553 7126 14 musculoskeletal darkolivegreen 7126, 553 1782, 157 1781, 137 1781, 136 1782, 123 -0.0839 0.0441 0.0571 1.243 0.92 0.843 1 -0.133 0.121 0.271 0.5666 0.875 0.69 1.11 -0.134 0.122 0.27 0.5686 0.875 0.689 1.11 -0.24 0.125 0.0549 1.26 0.787 0.616 1.01 PRS_PLINK_0.001 727.2 Bursitis disorders Both 26 262 14 musculoskeletal darkolivegreen 262, 26 66, 6 65, 7 65, 6 66, 7 0.0356 0.185 0.847 0.07202 1.04 0.721 1.49 0.171 0.539 0.752 0.1239 1.19 0.412 3.41 0.0781 0.551 0.887 0.05195 1.08 0.367 3.18 0.142 0.57 0.803 0.09522 1.15 0.377 3.52 PRS_PLINK_0.001 727.4 Ganglion and cyst of synovium, tendon, and bursa Both 735 8150 14 musculoskeletal darkolivegreen 8150, 735 2037, 170 2037, 197 2037, 168 2038, 200 0.018 0.0389 0.644 0.1911 1.02 0.943 1.1 0.145 0.109 0.183 0.7364 1.16 0.934 1.43 -0.0161 0.113 0.887 0.05226 0.984 0.788 1.23 0.154 0.109 0.157 0.8041 1.17 0.942 1.44 PRS_PLINK_0.001 727.5 Rupture of synovium Both 118 1511 14 musculoskeletal darkolivegreen 1511, 118 378, 22 378, 26 377, 37 378, 33 0.127 0.0949 0.181 0.7413 1.14 0.943 1.37 0.187 0.291 0.52 0.2841 1.21 0.682 2.13 0.521 0.275 0.0584 1.234 1.68 0.982 2.89 0.344 0.283 0.224 0.6505 1.41 0.811 2.45 PRS_PLINK_0.001 727.6 Rupture of tendon, nontraumatic Both 69 904 14 musculoskeletal darkolivegreen 904, 69 226, 10 226, 17 226, 17 226, 25 0.325 0.126 0.0101 1.996 1.38 1.08 1.77 0.565 0.393 0.15 0.8234 1.76 0.815 3.8 0.452 0.388 0.243 0.6136 1.57 0.735 3.36 0.921 0.372 0.0134 1.874 2.51 1.21 5.21 PRS_PLINK_0.001 727.7 Contracture of tendon (sheath) Both 23 404 14 musculoskeletal darkolivegreen 404, 23 101, 5 101, 5 101, 8 101, 5 0.139 0.205 0.495 0.3053 1.15 0.77 1.72 -0.00357 0.56 0.995 0.002214 0.996 0.332 2.99 0.379 0.527 0.472 0.3262 1.46 0.52 4.11 -0.0973 0.593 0.87 0.06059 0.907 0.284 2.9 PRS_PLINK_0.001 728 Disorders of muscle, ligament, and fascia Both 810 9240 14 musculoskeletal darkolivegreen 9240, 810 2310, 169 2310, 191 2310, 204 2310, 246 0.113 0.0369 0.00219 2.659 1.12 1.04 1.2 0.121 0.109 0.267 0.5739 1.13 0.911 1.4 0.197 0.108 0.0693 1.16 1.22 0.985 1.5 0.371 0.104 0.000376 3.425 1.45 1.18 1.78 PRS_PLINK_0.001 728.2 Laxity of ligament or hypermobility syndrome Both 100 1114 14 musculoskeletal darkolivegreen 1114, 100 279, 25 278, 27 278, 28 279, 20 -0.0502 0.103 0.626 0.2037 0.951 0.778 1.16 -0.0152 0.288 0.958 0.01867 0.985 0.56 1.73 0.119 0.284 0.675 0.1708 1.13 0.646 1.97 -0.288 0.308 0.351 0.4549 0.75 0.41 1.37 PRS_PLINK_0.001 728.7 Fasciitis Both 828 9606 14 musculoskeletal darkolivegreen 9606, 828 2402, 177 2401, 195 2401, 207 2402, 249 0.0974 0.0364 0.00741 2.13 1.1 1.03 1.18 0.103 0.108 0.34 0.4689 1.11 0.898 1.37 0.168 0.107 0.114 0.9426 1.18 0.96 1.46 0.337 0.103 0.00105 2.98 1.4 1.14 1.71 PRS_PLINK_0.001 728.71 Contracture of palmar fascia [Dupuytren's disease] Both 767 8680 14 musculoskeletal darkolivegreen 8680, 767 2170, 157 2170, 182 2170, 189 2170, 239 0.123 0.0377 0.0011 2.958 1.13 1.05 1.22 0.149 0.113 0.186 0.7301 1.16 0.931 1.45 0.192 0.112 0.0876 1.057 1.21 0.972 1.51 0.417 0.107 0.000104 3.984 1.52 1.23 1.87 PRS_PLINK_0.001 729 Other disorders of soft tissues Both 958 15389 14 musculoskeletal darkolivegreen 15389, 958 3848, 247 3847, 228 3847, 248 3847, 235 0.00202 0.0335 0.952 0.02141 1 0.938 1.07 -0.0749 0.0944 0.427 0.3693 0.928 0.771 1.12 0.0229 0.0928 0.805 0.09394 1.02 0.853 1.23 -0.0476 0.0941 0.613 0.2125 0.954 0.793 1.15 PRS_PLINK_0.001 729.1 Rheumatism, unspecified and fibrositis Both 126 2631 14 musculoskeletal darkolivegreen 2631, 126 658, 32 658, 31 657, 37 658, 26 -0.0573 0.0877 0.513 0.2897 0.944 0.795 1.12 -0.0291 0.251 0.908 0.04199 0.971 0.594 1.59 0.158 0.242 0.513 0.2902 1.17 0.729 1.88 -0.23 0.263 0.381 0.4188 0.795 0.475 1.33 PRS_PLINK_0.001 729.3 Panniculitis Both 19 266 14 musculoskeletal darkolivegreen 266, 19 67, 2 66, 2 66, 9 67, 6 0.316 0.214 0.141 0.8502 1.37 0.901 2.09 -0.397 0.82 0.629 0.2015 0.673 0.135 3.36 1.4 0.681 0.0394 1.404 4.07 1.07 15.5 1.25 0.748 0.0947 1.024 3.49 0.806 15.1 PRS_PLINK_0.001 731 Osteitis deformans and osteopathies associated with other disorders classified elsewhere Both 65 761 14 musculoskeletal darkolivegreen 761, 65 191, 16 190, 17 190, 13 190, 19 0.0537 0.132 0.684 0.1648 1.06 0.815 1.37 0.131 0.354 0.711 0.1479 1.14 0.569 2.28 -0.21 0.374 0.575 0.2407 0.811 0.389 1.69 0.244 0.347 0.482 0.3166 1.28 0.646 2.52 PRS_PLINK_0.001 731.1 Osteitis deformans [Paget's disease of bone] Both 61 732 14 musculoskeletal darkolivegreen 732, 61 183, 14 183, 17 183, 13 183, 17 0.0798 0.137 0.561 0.2513 1.08 0.828 1.42 0.307 0.37 0.406 0.3909 1.36 0.658 2.81 -0.0161 0.389 0.967 0.01461 0.984 0.459 2.11 0.271 0.368 0.461 0.3358 1.31 0.638 2.69 PRS_PLINK_0.001 732 Osteochondropathies Both 105 1219 14 musculoskeletal darkolivegreen 1219, 105 305, 27 305, 30 304, 27 305, 21 -0.0396 0.103 0.701 0.1541 0.961 0.785 1.18 0.0909 0.274 0.74 0.1307 1.1 0.64 1.87 0.0196 0.278 0.944 0.02511 1.02 0.591 1.76 -0.296 0.298 0.32 0.4946 0.744 0.415 1.33 PRS_PLINK_0.001 732.1 Juvenile osteochondrosis Both 47 542 14 musculoskeletal darkolivegreen 542, 47 136, 13 135, 14 135, 11 136, 9 -0.0441 0.157 0.779 0.1084 0.957 0.703 1.3 0.0788 0.392 0.841 0.07539 1.08 0.502 2.33 -0.166 0.409 0.684 0.1648 0.847 0.38 1.89 -0.204 0.437 0.64 0.194 0.815 0.346 1.92 PRS_PLINK_0.001 732.7 Osteochondritis dissecans Both 13 155 14 musculoskeletal darkolivegreen 155, 13 39, 3 39, 4 38, 3 39, 3 -0.189 0.266 0.478 0.3204 0.828 0.491 1.4 0.375 0.794 0.636 0.1965 1.46 0.307 6.89 0.483 0.77 0.531 0.2751 1.62 0.358 7.34 0.665 0.806 0.409 0.3881 1.94 0.401 9.43 PRS_PLINK_0.001 733 Other disorders of bone and cartilage Both 371 4528 14 musculoskeletal darkolivegreen 4528, 371 1132, 97 1132, 87 1132, 92 1132, 95 -0.0191 0.054 0.724 0.1404 0.981 0.883 1.09 -0.142 0.153 0.354 0.4505 0.868 0.643 1.17 -0.0634 0.151 0.674 0.171 0.939 0.698 1.26 -0.0512 0.15 0.733 0.1351 0.95 0.708 1.27 PRS_PLINK_0.001 733.2 Cyst of bone Both 66 779 14 musculoskeletal darkolivegreen 779, 66 195, 18 195, 14 194, 19 195, 15 -0.0576 0.13 0.659 0.1811 0.944 0.731 1.22 -0.305 0.357 0.393 0.4056 0.737 0.366 1.48 0.125 0.339 0.713 0.1471 1.13 0.583 2.2 -0.215 0.355 0.544 0.2641 0.806 0.402 1.62 PRS_PLINK_0.001 733.4 Aseptic necrosis of bone Both 109 1333 14 musculoskeletal darkolivegreen 1333, 109 334, 30 333, 20 333, 30 333, 29 0.0504 0.0968 0.603 0.2197 1.05 0.87 1.27 -0.364 0.292 0.213 0.6724 0.695 0.392 1.23 -0.0733 0.268 0.784 0.1055 0.929 0.55 1.57 -0.0411 0.268 0.878 0.05627 0.96 0.567 1.62 PRS_PLINK_0.001 733.6 Costochondritis Both 13 333 14 musculoskeletal darkolivegreen 333, 13 84, 4 83, 3 83, 1 83, 5 0.00453 0.26 0.986 0.006084 1 0.604 1.67 -0.82 0.729 0.261 0.5834 0.441 0.106 1.84 -1.22 0.827 0.14 0.8531 0.295 0.0585 1.49 0.193 0.635 0.761 0.1185 1.21 0.349 4.22 PRS_PLINK_0.001 733.8 Malunion and nonunion of fracture Both 237 3258 14 musculoskeletal darkolivegreen 3258, 237 815, 65 814, 53 814, 62 815, 57 -0.00464 0.0671 0.945 0.02459 0.995 0.873 1.14 -0.191 0.19 0.314 0.5032 0.826 0.57 1.2 -0.0338 0.183 0.854 0.06871 0.967 0.675 1.38 -0.137 0.187 0.465 0.3326 0.872 0.605 1.26 PRS_PLINK_0.001 733.9 Chondromalacia Both 20 327 14 musculoskeletal darkolivegreen 327, 20 82, 5 82, 6 81, 5 82, 4 -0.164 0.212 0.44 0.3568 0.849 0.56 1.29 0.201 0.579 0.728 0.1378 1.22 0.393 3.81 0.039 0.59 0.947 0.02347 1.04 0.327 3.31 -0.0165 0.632 0.979 0.009156 0.984 0.285 3.39 PRS_PLINK_0.001 735 Acquired foot deformities Both 2164 24807 14 musculoskeletal darkolivegreen 24807, 2164 6202, 590 6202, 533 6201, 522 6202, 518 -0.0418 0.0225 0.0625 1.204 0.959 0.918 1 -0.1 0.0624 0.109 0.9638 0.905 0.801 1.02 -0.123 0.0628 0.0511 1.292 0.885 0.782 1 -0.136 0.063 0.0307 1.513 0.873 0.771 0.987 PRS_PLINK_0.001 735.1 Flat foot Both 51 528 14 musculoskeletal darkolivegreen 528, 51 132, 12 132, 13 132, 15 132, 11 -0.0593 0.148 0.688 0.1624 0.942 0.705 1.26 0.113 0.402 0.778 0.1088 1.12 0.509 2.46 0.265 0.397 0.504 0.2975 1.3 0.599 2.84 -0.00369 0.418 0.993 0.003069 0.996 0.439 2.26 PRS_PLINK_0.001 735.2 Acquired toe deformities Both 1083 12760 14 musculoskeletal darkolivegreen 12760, 1083 3190, 299 3190, 268 3190, 264 3190, 252 -0.0508 0.0319 0.111 0.9535 0.95 0.893 1.01 -0.101 0.0877 0.251 0.5998 0.904 0.761 1.07 -0.124 0.0882 0.161 0.7924 0.884 0.743 1.05 -0.163 0.0893 0.0684 1.165 0.85 0.713 1.01 PRS_PLINK_0.001 735.21 Hammer toe (acquired) Both 399 4877 14 musculoskeletal darkolivegreen 4877, 399 1220, 106 1219, 94 1219, 85 1219, 114 0.00881 0.052 0.866 0.06272 1.01 0.911 1.12 -0.104 0.147 0.48 0.319 0.901 0.676 1.2 -0.221 0.151 0.144 0.8411 0.802 0.597 1.08 0.0907 0.141 0.52 0.2837 1.09 0.83 1.44 PRS_PLINK_0.001 735.23 Hallux rigidus Both 344 3957 14 musculoskeletal darkolivegreen 3957, 344 990, 92 989, 100 989, 81 989, 71 -0.0891 0.0564 0.114 0.9429 0.915 0.819 1.02 0.0862 0.151 0.568 0.246 1.09 0.811 1.46 -0.116 0.158 0.461 0.3358 0.89 0.653 1.21 -0.241 0.163 0.14 0.8524 0.786 0.571 1.08 PRS_PLINK_0.001 735.3 Hallux valgus (Bunion) Both 1517 17143 14 musculoskeletal darkolivegreen 17143, 1517 4286, 409 4286, 359 4285, 371 4286, 377 -0.0263 0.0268 0.326 0.4863 0.974 0.924 1.03 -0.131 0.0754 0.0819 1.087 0.877 0.756 1.02 -0.098 0.075 0.191 0.7184 0.907 0.783 1.05 -0.0967 0.0748 0.196 0.7071 0.908 0.784 1.05 PRS_PLINK_0.001 736 Other acquired deformities of limbs Both 320 4091 14 musculoskeletal darkolivegreen 4091, 320 1023, 76 1023, 96 1022, 82 1023, 66 -0.0165 0.0577 0.775 0.1105 0.984 0.878 1.1 0.218 0.159 0.17 0.77 1.24 0.911 1.7 0.0788 0.164 0.631 0.1999 1.08 0.784 1.49 -0.175 0.173 0.313 0.505 0.84 0.598 1.18 PRS_PLINK_0.001 736.2 Acquired deformities of finger Both 40 603 14 musculoskeletal darkolivegreen 603, 40 151, 15 151, 9 150, 9 151, 7 -0.286 0.161 0.0753 1.123 0.751 0.548 1.03 -0.487 0.415 0.24 0.6195 0.614 0.273 1.38 -0.686 0.429 0.11 0.9579 0.504 0.217 1.17 -0.809 0.456 0.0764 1.117 0.445 0.182 1.09 PRS_PLINK_0.001 737 Curvature of spine Both 188 2749 14 musculoskeletal darkolivegreen 2749, 188 688, 48 687, 49 687, 51 687, 40 -0.0274 0.0754 0.717 0.1448 0.973 0.839 1.13 0.0218 0.207 0.916 0.03794 1.02 0.681 1.53 0.0446 0.207 0.829 0.08118 1.05 0.697 1.57 -0.211 0.219 0.335 0.4743 0.809 0.526 1.24 PRS_PLINK_0.001 737.3 Kyphoscoliosis and scoliosis Both 176 2556 14 musculoskeletal darkolivegreen 2556, 176 639, 46 639, 46 639, 46 639, 38 -0.0407 0.0779 0.601 0.2208 0.96 0.824 1.12 0.00512 0.213 0.981 0.008412 1.01 0.662 1.53 -0.0145 0.214 0.946 0.02402 0.986 0.648 1.5 -0.201 0.225 0.372 0.4296 0.818 0.527 1.27 PRS_PLINK_0.001 738 Other acquired musculoskeletal deformity Both 350 4807 14 musculoskeletal darkolivegreen 4807, 350 1202, 101 1202, 79 1201, 97 1202, 73 -0.0911 0.0554 0.0999 1 0.913 0.819 1.02 -0.267 0.155 0.0856 1.068 0.766 0.565 1.04 -0.0598 0.148 0.685 0.1642 0.942 0.705 1.26 -0.337 0.159 0.0342 1.466 0.714 0.523 0.975 PRS_PLINK_0.001 738.4 Acquired spondylolisthesis Both 272 3722 14 musculoskeletal darkolivegreen 3722, 272 931, 82 930, 56 930, 74 931, 60 -0.0844 0.0625 0.176 0.7534 0.919 0.813 1.04 -0.398 0.179 0.026 1.585 0.672 0.473 0.954 -0.12 0.166 0.469 0.3285 0.887 0.64 1.23 -0.302 0.176 0.0858 1.067 0.739 0.524 1.04 PRS_PLINK_0.001 739 Contracture of joint Both 89 1208 14 musculoskeletal darkolivegreen 1208, 89 302, 30 302, 22 302, 16 302, 21 -0.0882 0.106 0.405 0.3929 0.916 0.744 1.13 -0.337 0.286 0.239 0.622 0.714 0.408 1.25 -0.552 0.311 0.0757 1.121 0.576 0.313 1.06 -0.348 0.29 0.23 0.6375 0.706 0.4 1.25 PRS_PLINK_0.001 740 Osteoarthrosis Both 5273 60354 14 musculoskeletal darkolivegreen 60354, 5273 15088, 1260 15088, 1333 15088, 1324 15089, 1356 0.0114 0.0145 0.43 0.3669 1.01 0.983 1.04 0.05 0.041 0.223 0.6516 1.05 0.97 1.14 0.0379 0.0412 0.357 0.4471 1.04 0.958 1.13 0.0531 0.0411 0.196 0.7083 1.05 0.973 1.14 PRS_PLINK_0.001 740.1 Osteoarthritis; localized Both 3556 42723 14 musculoskeletal darkolivegreen 42723, 3556 10681, 866 10681, 910 10680, 879 10681, 901 0.00862 0.0175 0.621 0.2066 1.01 0.975 1.04 0.0497 0.0494 0.315 0.5023 1.05 0.954 1.16 0.0106 0.0499 0.832 0.08008 1.01 0.916 1.11 0.0303 0.0498 0.543 0.265 1.03 0.935 1.14 PRS_PLINK_0.001 740.11 Osteoarthrosis, localized, primary Both 1810 22083 14 musculoskeletal darkolivegreen 22083, 1810 5521, 424 5521, 470 5520, 463 5521, 453 0.0071 0.0245 0.772 0.1122 1.01 0.96 1.06 0.105 0.0697 0.133 0.8749 1.11 0.969 1.27 0.0848 0.07 0.226 0.6463 1.09 0.949 1.25 0.0569 0.0706 0.42 0.3764 1.06 0.922 1.22 PRS_PLINK_0.001 740.12 Osteoarthrosis, localized, secondary Both 69 913 14 musculoskeletal darkolivegreen 913, 69 229, 20 228, 21 228, 17 228, 11 -0.191 0.123 0.12 0.9206 0.826 0.65 1.05 0.097 0.321 0.763 0.1177 1.1 0.587 2.07 -0.149 0.338 0.66 0.1806 0.862 0.444 1.67 -0.587 0.375 0.118 0.9299 0.556 0.267 1.16 PRS_PLINK_0.001 740.2 Osteoarthrosis, generalized Both 62 1582 14 musculoskeletal darkolivegreen 1582, 62 396, 23 395, 8 395, 15 396, 16 -0.166 0.127 0.191 0.718 0.847 0.661 1.09 -1.07 0.392 0.00613 2.212 0.342 0.159 0.736 -0.425 0.328 0.195 0.7092 0.654 0.344 1.24 -0.379 0.32 0.236 0.6266 0.685 0.366 1.28 PRS_PLINK_0.001 740.9 Osteoarthrosis NOS Both 2043 30776 14 musculoskeletal darkolivegreen 30776, 2043 7693, 485 7694, 508 7694, 532 7694, 518 0.0186 0.0229 0.417 0.3803 1.02 0.974 1.07 0.0477 0.0655 0.466 0.3319 1.05 0.923 1.19 0.0929 0.0649 0.152 0.8173 1.1 0.966 1.25 0.069 0.0655 0.292 0.5342 1.07 0.942 1.22 PRS_PLINK_0.001 741 Symptoms and disorders of the joints Both 658 9105 14 musculoskeletal darkolivegreen 9105, 658 2277, 148 2276, 174 2276, 170 2276, 166 0.0122 0.0406 0.764 0.1172 1.01 0.935 1.1 0.151 0.116 0.192 0.7157 1.16 0.927 1.46 0.135 0.116 0.245 0.6108 1.14 0.912 1.44 0.103 0.117 0.38 0.42 1.11 0.881 1.39 PRS_PLINK_0.001 741.1 Ankylosis of joint Both 14 263 14 musculoskeletal darkolivegreen 263, 14 66, 1 66, 5 65, 1 66, 7 0.534 0.26 0.0401 1.397 1.71 1.02 2.84 1.14 0.83 0.169 0.7723 3.13 0.616 15.9 -0.334 0.897 0.709 0.1491 0.716 0.123 4.15 1.34 0.813 0.0993 1.003 3.82 0.776 18.8 PRS_PLINK_0.001 741.2 Stiffness of joint Both 115 1565 14 musculoskeletal darkolivegreen 1565, 115 392, 21 391, 36 391, 30 391, 28 0.0253 0.0963 0.793 0.1008 1.03 0.849 1.24 0.594 0.28 0.0335 1.475 1.81 1.05 3.13 0.381 0.287 0.184 0.7352 1.46 0.834 2.57 0.281 0.292 0.336 0.4741 1.32 0.748 2.35 PRS_PLINK_0.001 741.3 Difficulty in walking Both 10 392 14 musculoskeletal darkolivegreen 392, 10 98, 1 98, 3 98, 2 98, 4 0.264 0.299 0.377 0.4242 1.3 0.725 2.34 1.09 0.864 0.207 0.6848 2.98 0.547 16.2 0.646 0.816 0.429 0.368 1.91 0.386 9.44 1.08 0.792 0.172 0.7649 2.95 0.625 13.9 PRS_PLINK_0.001 741.4 Joint effusions Both 230 3651 14 musculoskeletal darkolivegreen 3651, 230 913, 55 913, 55 912, 66 913, 54 0.0036 0.068 0.958 0.01873 1 0.878 1.15 0.0259 0.195 0.894 0.04857 1.03 0.701 1.5 0.174 0.187 0.353 0.4521 1.19 0.825 1.72 0.00356 0.196 0.985 0.00636 1 0.684 1.47 PRS_PLINK_0.001 741.5 Hemarthrosis Both 18 288 14 musculoskeletal darkolivegreen 288, 18 72, 3 72, 10 72, 1 72, 4 -0.0906 0.222 0.684 0.1653 0.913 0.591 1.41 1.07 0.609 0.0796 1.099 2.91 0.881 9.59 -1.13 0.864 0.19 0.7207 0.323 0.0593 1.75 -0.124 0.683 0.856 0.06767 0.883 0.231 3.37 PRS_PLINK_0.001 741.6 Villonodular synovitis Both 10 127 14 musculoskeletal darkolivegreen 127, 10 32, 5 32, 0 31, 2 32, 3 -0.405 0.296 0.171 0.7662 0.667 0.373 1.19 -2.28 1.2 0.0578 1.238 0.103 0.00975 1.08 -0.73 0.761 0.337 0.4718 0.482 0.108 2.14 -0.338 0.731 0.644 0.1912 0.713 0.17 2.99 PRS_PLINK_0.001 742 Derangement of joint, non-traumatic Both 604 7450 14 musculoskeletal darkolivegreen 7450, 604 1863, 136 1862, 166 1862, 146 1863, 156 0.011 0.0421 0.794 0.1 1.01 0.931 1.1 0.202 0.12 0.0916 1.038 1.22 0.968 1.55 0.0753 0.123 0.541 0.2666 1.08 0.847 1.37 0.147 0.122 0.228 0.6421 1.16 0.912 1.47 PRS_PLINK_0.001 742.1 Loose body in joint Both 77 881 14 musculoskeletal darkolivegreen 881, 77 221, 15 220, 24 220, 13 220, 25 0.061 0.117 0.601 0.2213 1.06 0.846 1.34 0.448 0.333 0.179 0.7471 1.56 0.814 3.01 -0.194 0.374 0.605 0.2182 0.824 0.396 1.72 0.518 0.333 0.12 0.9219 1.68 0.874 3.22 PRS_PLINK_0.001 742.2 Pathological, developmental or recurrent dislocation Both 18 243 14 musculoskeletal darkolivegreen 243, 18 61, 0 61, 7 60, 3 61, 8 0.39 0.23 0.0909 1.041 1.48 0.94 2.32 3.24 1.35 0.0161 1.794 25.6 1.83 358 1.77 1.09 0.105 0.9782 5.85 0.691 49.6 2.73 1.22 0.0256 1.592 15.3 1.39 167 PRS_PLINK_0.001 742.8 Articular cartilage disorder Both 89 1332 14 musculoskeletal darkolivegreen 1332, 89 333, 18 333, 25 333, 26 333, 20 0.0382 0.11 0.729 0.1372 1.04 0.837 1.29 0.297 0.309 0.336 0.4739 1.35 0.735 2.47 0.409 0.307 0.183 0.7369 1.51 0.824 2.75 0.151 0.322 0.638 0.1953 1.16 0.619 2.18 PRS_PLINK_0.001 742.9 Other derangement of joint Both 429 5171 14 musculoskeletal darkolivegreen 5171, 429 1293, 104 1293, 117 1292, 102 1293, 106 -0.0212 0.0497 0.67 0.1736 0.979 0.888 1.08 0.115 0.14 0.41 0.3868 1.12 0.853 1.47 -0.0171 0.144 0.906 0.04291 0.983 0.741 1.3 0.022 0.144 0.878 0.05638 1.02 0.771 1.35 PRS_PLINK_0.001 743 Osteoporosis, osteopenia and pathological fracture Both 1317 18376 14 musculoskeletal darkolivegreen 18376, 1317 4593, 334 4594, 338 4594, 321 4594, 324 -0.021 0.0287 0.464 0.3337 0.979 0.926 1.04 0.0157 0.0799 0.844 0.07374 1.02 0.869 1.19 -0.0394 0.0809 0.626 0.2034 0.961 0.82 1.13 -0.0137 0.081 0.866 0.06243 0.986 0.842 1.16 PRS_PLINK_0.001 743.1 Osteoporosis Both 1089 15385 14 musculoskeletal darkolivegreen 15385, 1089 3846, 268 3846, 282 3846, 268 3846, 271 0.00161 0.0315 0.959 0.0181 1 0.942 1.07 0.0531 0.0882 0.547 0.2619 1.05 0.887 1.25 -0.00602 0.0894 0.946 0.02395 0.994 0.834 1.18 0.0207 0.0894 0.817 0.08762 1.02 0.857 1.22 PRS_PLINK_0.001 743.11 Osteoporosis NOS Both 937 13345 14 musculoskeletal darkolivegreen 13345, 937 3336, 229 3336, 251 3336, 232 3336, 225 -0.0115 0.0339 0.735 0.1336 0.989 0.925 1.06 0.0996 0.0945 0.292 0.5349 1.1 0.918 1.33 0.00677 0.0963 0.944 0.02504 1.01 0.834 1.22 -0.00106 0.0973 0.991 0.003778 0.999 0.826 1.21 PRS_PLINK_0.001 743.13 Other specified osteoporosis Both 82 1292 14 musculoskeletal darkolivegreen 1292, 82 323, 17 323, 18 323, 16 323, 31 0.178 0.11 0.106 0.9757 1.19 0.963 1.48 -0.00687 0.335 0.984 0.00716 0.993 0.515 1.92 -0.0563 0.34 0.869 0.06119 0.945 0.485 1.84 0.59 0.304 0.0526 1.279 1.8 0.993 3.28 PRS_PLINK_0.001 743.2 Pathologic fracture Both 66 1248 14 musculoskeletal darkolivegreen 1248, 66 311, 20 312, 10 312, 18 312, 18 -0.0401 0.123 0.745 0.1278 0.961 0.754 1.22 -0.659 0.374 0.0781 1.107 0.517 0.249 1.08 -0.0694 0.322 0.829 0.08132 0.933 0.497 1.75 -0.0508 0.324 0.875 0.05781 0.95 0.504 1.79 PRS_PLINK_0.001 743.9 Osteopenia or other disorder of bone and cartilage Both 180 2066 14 musculoskeletal darkolivegreen 2066, 180 517, 56 516, 51 516, 38 517, 35 -0.198 0.0793 0.0126 1.9 0.82 0.702 0.958 -0.0965 0.202 0.632 0.199 0.908 0.611 1.35 -0.387 0.217 0.074 1.131 0.679 0.444 1.04 -0.429 0.222 0.0535 1.272 0.651 0.421 1.01 PRS_PLINK_0.001 745 Pain in joint Both 1406 20382 14 musculoskeletal darkolivegreen 20382, 1406 5096, 333 5095, 353 5095, 359 5096, 361 0.00618 0.0276 0.823 0.08455 1.01 0.953 1.06 0.0618 0.0789 0.433 0.3633 1.06 0.911 1.24 0.0814 0.0788 0.301 0.5208 1.08 0.93 1.27 0.0811 0.0788 0.303 0.5182 1.08 0.929 1.27 PRS_PLINK_0.001 747 Cardiac and circulatory congenital anomalies Both 470 6788 15 congenital anomalies mediumspringgreen 6788, 470 1697, 127 1697, 140 1697, 104 1697, 99 -0.0934 0.0474 0.0488 1.312 0.911 0.83 0.999 0.0952 0.127 0.452 0.3448 1.1 0.858 1.41 -0.204 0.136 0.135 0.8704 0.816 0.625 1.07 -0.252 0.139 0.0695 1.158 0.777 0.592 1.02 PRS_PLINK_0.001 747.1 Cardiac congenital anomalies Both 432 6367 15 congenital anomalies mediumspringgreen 6367, 432 1592, 112 1592, 129 1591, 100 1592, 91 -0.0734 0.0493 0.137 0.8635 0.929 0.844 1.02 0.14 0.133 0.294 0.5323 1.15 0.886 1.49 -0.11 0.141 0.438 0.3588 0.896 0.679 1.18 -0.204 0.146 0.163 0.789 0.816 0.613 1.09 PRS_PLINK_0.001 747.11 Cardiac shunt/ heart septal defect Both 118 1506 15 congenital anomalies mediumspringgreen 1506, 118 377, 32 376, 27 376, 25 377, 34 0.0358 0.0941 0.704 0.1525 1.04 0.862 1.25 -0.143 0.266 0.59 0.2292 0.867 0.515 1.46 -0.245 0.271 0.367 0.4358 0.783 0.46 1.33 0.0898 0.255 0.724 0.14 1.09 0.664 1.8 PRS_PLINK_0.001 747.12 Valvular heart disease/ heart chambers Both 47 628 15 congenital anomalies mediumspringgreen 628, 47 157, 14 157, 15 157, 7 157, 11 -0.147 0.15 0.326 0.4864 0.863 0.644 1.16 0.0874 0.374 0.815 0.08878 1.09 0.525 2.27 -0.722 0.451 0.11 0.9605 0.486 0.201 1.18 -0.372 0.418 0.374 0.4267 0.69 0.304 1.57 PRS_PLINK_0.001 747.13 Congenital anomalies of great vessels Both 256 4210 15 congenital anomalies mediumspringgreen 4210, 256 1053, 68 1052, 81 1052, 59 1053, 48 -0.121 0.0637 0.0585 1.232 0.886 0.782 1 0.164 0.168 0.33 0.4809 1.18 0.847 1.64 -0.128 0.182 0.482 0.3167 0.88 0.617 1.26 -0.352 0.193 0.0685 1.165 0.703 0.482 1.03 PRS_PLINK_0.001 747.2 Congenital anomalies of peripheral vascular system Both 34 428 15 congenital anomalies mediumspringgreen 428, 34 107, 14 107, 11 107, 1 107, 8 -0.365 0.171 0.0331 1.481 0.694 0.496 0.971 -0.281 0.42 0.503 0.2982 0.755 0.331 1.72 -2.4 0.8 0.00271 2.567 0.0909 0.019 0.436 -0.626 0.447 0.162 0.7918 0.535 0.223 1.28 PRS_PLINK_0.001 748 Anomalies of respiratory system, congenital Both 12 134 15 congenital anomalies mediumspringgreen 134, 12 34, 2 33, 4 33, 4 34, 2 0.00903 0.246 0.971 0.01291 1.01 0.623 1.63 0.357 0.835 0.669 0.1746 1.43 0.278 7.35 0.956 0.851 0.261 0.583 2.6 0.491 13.8 -0.247 0.829 0.765 0.1161 0.781 0.154 3.97 PRS_PLINK_0.001 749 Congenital anomalies of face and neck Both 69 744 15 congenital anomalies mediumspringgreen 744, 69 186, 16 186, 17 186, 19 186, 17 0.0189 0.131 0.885 0.05317 1.02 0.789 1.32 0.0297 0.352 0.933 0.03021 1.03 0.516 2.06 0.246 0.347 0.479 0.3199 1.28 0.648 2.52 -0.00739 0.36 0.984 0.00716 0.993 0.49 2.01 PRS_PLINK_0.001 750 Digestive congenital anomalies Both 163 1718 15 congenital anomalies mediumspringgreen 1718, 163 430, 43 429, 48 429, 33 430, 39 -0.0886 0.0833 0.287 0.5415 0.915 0.777 1.08 0.0944 0.219 0.666 0.1762 1.1 0.715 1.69 -0.25 0.237 0.291 0.5357 0.779 0.49 1.24 -0.0731 0.229 0.749 0.1253 0.929 0.593 1.46 PRS_PLINK_0.001 750.1 Upper gastrointestinal congenital anomalies Both 71 805 15 congenital anomalies mediumspringgreen 805, 71 202, 22 201, 21 201, 15 201, 13 -0.26 0.125 0.0371 1.43 0.771 0.604 0.985 -0.00283 0.317 0.993 0.003097 0.997 0.535 1.86 -0.36 0.338 0.288 0.5404 0.698 0.36 1.36 -0.494 0.35 0.158 0.8018 0.61 0.307 1.21 PRS_PLINK_0.001 750.13 Congenital anomalies of mouth/tongue Both 39 467 15 congenital anomalies mediumspringgreen 467, 39 117, 8 117, 12 116, 12 117, 7 -0.0164 0.17 0.923 0.03471 0.984 0.705 1.37 0.36 0.45 0.424 0.3723 1.43 0.593 3.47 0.429 0.449 0.34 0.4691 1.54 0.637 3.7 -0.0416 0.493 0.933 0.0302 0.959 0.365 2.52 PRS_PLINK_0.001 750.2 Lower gastrointestinal congenital anomalies Both 89 923 15 congenital anomalies mediumspringgreen 923, 89 231, 21 231, 26 230, 17 231, 25 0.0327 0.112 0.77 0.1134 1.03 0.83 1.29 0.195 0.301 0.517 0.2864 1.22 0.673 2.19 -0.221 0.33 0.503 0.2985 0.802 0.42 1.53 0.211 0.304 0.487 0.312 1.24 0.68 2.24 PRS_PLINK_0.001 750.21 Congenital anomalies of intestine Both 58 592 15 congenital anomalies mediumspringgreen 592, 58 148, 11 148, 19 148, 14 148, 14 0.032 0.143 0.823 0.08477 1.03 0.78 1.37 0.526 0.386 0.173 0.7629 1.69 0.795 3.61 0.318 0.404 0.432 0.3649 1.37 0.622 3.04 0.45 0.415 0.278 0.5553 1.57 0.695 3.54 PRS_PLINK_0.001 750.22 Congenital anomaly of gallbladder, bile ducts, liver, pancreas Both 29 301 15 congenital anomalies mediumspringgreen 301, 29 76, 8 75, 7 75, 4 75, 10 0.119 0.189 0.529 0.2767 1.13 0.778 1.63 -0.182 0.512 0.722 0.1414 0.833 0.305 2.28 -0.677 0.581 0.244 0.6134 0.508 0.163 1.59 0.207 0.476 0.664 0.1777 1.23 0.483 3.13 PRS_PLINK_0.001 751 Genitourinary congenital anomalies Both 358 4024 15 congenital anomalies mediumspringgreen 4024, 358 1006, 83 1006, 91 1006, 92 1006, 92 0.039 0.0553 0.48 0.3186 1.04 0.933 1.16 0.08 0.157 0.611 0.214 1.08 0.796 1.47 0.0943 0.157 0.548 0.2612 1.1 0.808 1.5 0.097 0.157 0.538 0.2693 1.1 0.809 1.5 PRS_PLINK_0.001 751.1 Congenital anomalies of genital organs Both 166 1875 15 congenital anomalies mediumspringgreen 1875, 166 469, 32 469, 43 468, 43 469, 48 0.113 0.0812 0.165 0.7812 1.12 0.955 1.31 0.309 0.239 0.196 0.707 1.36 0.852 2.18 0.315 0.238 0.186 0.7301 1.37 0.859 2.19 0.412 0.234 0.0789 1.103 1.51 0.954 2.39 PRS_PLINK_0.001 751.11 Congenital anomalies of female genital organs Female 115 1265 15 congenital anomalies mediumspringgreen 1265, 115 317, 22 316, 24 316, 34 316, 35 0.16 0.0971 0.0985 1.007 1.17 0.971 1.42 0.0922 0.298 0.757 0.1208 1.1 0.611 1.97 0.447 0.281 0.111 0.9533 1.56 0.902 2.71 0.439 0.28 0.116 0.9339 1.55 0.897 2.68 PRS_PLINK_0.001 751.12 Congenital anomalies of male genital organs Male 48 601 15 congenital anomalies mediumspringgreen 601, 48 151, 11 150, 17 150, 7 150, 13 0.0685 0.148 0.643 0.1915 1.07 0.801 1.43 0.466 0.394 0.237 0.6255 1.59 0.736 3.45 -0.205 0.473 0.665 0.1769 0.815 0.322 2.06 0.221 0.412 0.592 0.2278 1.25 0.556 2.8 PRS_PLINK_0.001 751.2 Congenital anomalies of urinary system Both 190 2143 15 congenital anomalies mediumspringgreen 2143, 190 536, 50 536, 44 535, 51 536, 45 -0.0152 0.0768 0.843 0.07411 0.985 0.847 1.14 -0.143 0.213 0.503 0.2982 0.867 0.571 1.32 -0.00356 0.207 0.986 0.00598 0.996 0.664 1.5 -0.11 0.214 0.609 0.2157 0.896 0.589 1.36 PRS_PLINK_0.001 751.21 Cystic kidney disease Both 88 1070 15 congenital anomalies mediumspringgreen 1070, 88 268, 26 267, 20 267, 26 268, 16 -0.132 0.117 0.259 0.5868 0.876 0.696 1.1 -0.258 0.302 0.393 0.4058 0.773 0.428 1.4 -0.0373 0.294 0.899 0.04627 0.963 0.542 1.71 -0.53 0.325 0.103 0.9885 0.589 0.312 1.11 PRS_PLINK_0.001 751.22 Other specified congenital anomalies of kidney Both 80 855 15 congenital anomalies mediumspringgreen 855, 80 214, 19 214, 14 213, 21 214, 26 0.148 0.117 0.205 0.6879 1.16 0.922 1.46 -0.303 0.357 0.397 0.4016 0.739 0.367 1.49 0.0422 0.324 0.897 0.04742 1.04 0.552 1.97 0.227 0.313 0.468 0.3299 1.26 0.68 2.32 PRS_PLINK_0.001 752 Nervous system congenital anomalies Both 56 876 15 congenital anomalies mediumspringgreen 876, 56 219, 17 219, 16 219, 11 219, 12 -0.142 0.129 0.273 0.5645 0.868 0.674 1.12 -0.0706 0.346 0.838 0.07656 0.932 0.473 1.84 -0.461 0.379 0.224 0.6491 0.631 0.3 1.33 -0.321 0.372 0.387 0.4121 0.725 0.35 1.5 PRS_PLINK_0.001 752.1 Neural tube defects Both 46 683 15 congenital anomalies mediumspringgreen 683, 46 171, 16 171, 11 170, 7 171, 12 -0.148 0.144 0.306 0.5137 0.863 0.65 1.14 -0.357 0.387 0.356 0.449 0.7 0.328 1.49 -0.87 0.439 0.0477 1.321 0.419 0.177 0.991 -0.257 0.382 0.502 0.2996 0.773 0.365 1.64 PRS_PLINK_0.001 752.11 Spina bifida Both 39 589 15 congenital anomalies mediumspringgreen 589, 39 148, 15 147, 12 147, 4 147, 8 -0.292 0.159 0.0662 1.179 0.747 0.547 1.02 -0.204 0.387 0.597 0.2239 0.815 0.382 1.74 -1.25 0.519 0.016 1.797 0.286 0.103 0.792 -0.571 0.429 0.183 0.7371 0.565 0.244 1.31 PRS_PLINK_0.001 752.2 Other specified congenital anomalies of nervous system Both 9 214 15 congenital anomalies mediumspringgreen 214, 9 54, 1 53, 4 53, 4 54, 0 -0.0447 0.277 0.872 0.05957 0.956 0.556 1.65 1.03 0.827 0.212 0.6728 2.8 0.555 14.2 1.06 0.842 0.209 0.6788 2.88 0.552 15 -0.5 1.08 0.642 0.1923 0.607 0.0737 5 PRS_PLINK_0.001 753 Congenital anomalies of the eye Both 37 313 15 congenital anomalies mediumspringgreen 313, 37 79, 6 78, 15 78, 8 78, 8 0.00263 0.168 0.987 0.005463 1 0.722 1.39 0.819 0.481 0.0889 1.051 2.27 0.883 5.82 0.186 0.545 0.733 0.1348 1.2 0.414 3.5 0.209 0.519 0.686 0.1634 1.23 0.446 3.41 PRS_PLINK_0.001 753.1 Congenital cataract and lens anomalies Both 20 196 15 congenital anomalies mediumspringgreen 196, 20 49, 3 49, 6 49, 5 49, 6 0.196 0.234 0.401 0.3971 1.22 0.77 1.92 0.354 0.659 0.592 0.228 1.42 0.391 5.19 0.37 0.683 0.588 0.2305 1.45 0.38 5.52 0.606 0.65 0.351 0.4545 1.83 0.513 6.55 PRS_PLINK_0.001 754 Congenital musculoskeletal deformities of spine Both 18 291 15 congenital anomalies mediumspringgreen 291, 18 73, 6 73, 6 72, 3 73, 3 -0.208 0.243 0.391 0.4081 0.812 0.504 1.31 0.234 0.592 0.692 0.1597 1.26 0.396 4.03 -0.514 0.657 0.434 0.3624 0.598 0.165 2.17 -0.469 0.656 0.474 0.3242 0.625 0.173 2.26 PRS_PLINK_0.001 755 Congenital anomalies of limbs Both 95 1160 15 congenital anomalies mediumspringgreen 1160, 95 290, 25 290, 23 290, 26 290, 21 0.000754 0.109 0.994 0.002396 1 0.808 1.24 -0.111 0.296 0.706 0.1511 0.895 0.501 1.6 0.0419 0.287 0.884 0.05369 1.04 0.594 1.83 -0.195 0.304 0.521 0.2834 0.822 0.453 1.49 PRS_PLINK_0.001 755.1 Congenital deformities of feet Both 43 556 15 congenital anomalies mediumspringgreen 556, 43 139, 11 139, 9 139, 10 139, 13 0.113 0.154 0.463 0.334 1.12 0.828 1.51 -0.199 0.438 0.65 0.1872 0.82 0.348 1.93 -0.0386 0.428 0.928 0.03241 0.962 0.416 2.22 0.158 0.415 0.703 0.1529 1.17 0.519 2.64 PRS_PLINK_0.001 755.6 Other congenital anomalies of lower limb, including pelvic girdle Both 38 411 15 congenital anomalies mediumspringgreen 411, 38 103, 11 103, 12 102, 9 103, 6 -0.152 0.166 0.361 0.4421 0.859 0.62 1.19 0.0583 0.43 0.892 0.0495 1.06 0.456 2.46 -0.226 0.456 0.62 0.2078 0.798 0.326 1.95 -0.62 0.509 0.224 0.6501 0.538 0.198 1.46 PRS_PLINK_0.001 755.61 Congenital hip dysplasia and deformity Both 26 274 15 congenital anomalies mediumspringgreen 274, 26 69, 7 68, 10 68, 6 69, 3 -0.182 0.202 0.367 0.435 0.834 0.562 1.24 0.543 0.522 0.298 0.5258 1.72 0.619 4.79 -0.0268 0.582 0.963 0.01624 0.974 0.311 3.05 -0.583 0.686 0.395 0.4032 0.558 0.146 2.14 PRS_PLINK_0.001 756 Other congenital musculoskeletal anomalies Both 107 1542 15 congenital anomalies mediumspringgreen 1542, 107 386, 26 385, 23 385, 26 386, 32 0.104 0.102 0.308 0.5119 1.11 0.908 1.36 -0.136 0.289 0.637 0.1961 0.872 0.495 1.54 -0.022 0.28 0.937 0.02806 0.978 0.565 1.69 0.21 0.268 0.432 0.3644 1.23 0.73 2.09 PRS_PLINK_0.001 756.3 Congenital anomalies of muscle, tendon, fascia, and connective tissue Both 21 212 15 congenital anomalies mediumspringgreen 212, 21 53, 1 53, 9 53, 7 53, 4 0.213 0.228 0.35 0.4555 1.24 0.792 1.93 1.82 0.817 0.0259 1.586 6.17 1.24 30.6 1.73 0.886 0.0505 1.297 5.66 0.996 32.1 1.85 0.981 0.0587 1.231 6.39 0.934 43.7 PRS_PLINK_0.001 756.5 Congenital osteodystrophies Both 74 1119 15 congenital anomalies mediumspringgreen 1119, 74 280, 21 280, 16 279, 15 280, 22 0.0251 0.119 0.834 0.07905 1.03 0.811 1.3 -0.271 0.333 0.416 0.3809 0.763 0.397 1.47 -0.332 0.334 0.32 0.4944 0.717 0.372 1.38 0.0451 0.306 0.883 0.05408 1.05 0.574 1.91 PRS_PLINK_0.001 758 Chromosomal anomalies and genetic disorders Both 37 456 15 congenital anomalies mediumspringgreen 456, 37 114, 9 114, 14 114, 5 114, 9 -0.186 0.166 0.261 0.5841 0.83 0.6 1.15 0.339 0.441 0.442 0.3542 1.4 0.591 3.33 -0.686 0.536 0.201 0.6979 0.504 0.176 1.44 0.116 0.48 0.808 0.09239 1.12 0.439 2.88 PRS_PLINK_0.001 758.1 Chromosomal anomalies Both 11 214 15 congenital anomalies mediumspringgreen 214, 11 54, 8 53, 1 53, 0 54, 2 -0.547 0.316 0.083 1.081 0.578 0.312 1.07 -1.46 0.811 0.0718 1.144 0.232 0.0473 1.14 -2.46 1.21 0.0419 1.378 0.0855 0.008 0.914 -0.413 0.751 0.583 0.2347 0.662 0.152 2.88 PRS_PLINK_0.001 759 Other and unspecified congenital anomalies Both 57 591 15 congenital anomalies mediumspringgreen 591, 57 148, 16 148, 16 147, 9 148, 16 -0.0366 0.142 0.796 0.09881 0.964 0.73 1.27 0.0388 0.362 0.915 0.03881 1.04 0.512 2.11 -0.542 0.408 0.183 0.7368 0.581 0.261 1.29 -0.0325 0.363 0.929 0.03208 0.968 0.475 1.97 PRS_PLINK_0.001 759.1 Anomalies of endocrine glands, congenital Both 31 264 15 congenital anomalies mediumspringgreen 264, 31 66, 3 66, 8 66, 4 66, 16 0.428 0.222 0.0539 1.268 1.53 0.993 2.37 0.958 0.632 0.129 0.8882 2.61 0.756 8.99 0.183 0.7 0.794 0.1001 1.2 0.305 4.73 1.67 0.621 0.00729 2.137 5.29 1.57 17.9 PRS_PLINK_0.001 760 Back pain Both 1792 28489 17 symptoms purple 28489, 1792 7122, 451 7122, 447 7122, 460 7122, 434 -0.00723 0.0244 0.767 0.1153 0.993 0.947 1.04 -0.0104 0.0688 0.88 0.05542 0.99 0.865 1.13 0.0149 0.0685 0.828 0.08184 1.01 0.888 1.16 -0.0449 0.0696 0.519 0.2851 0.956 0.834 1.1 PRS_PLINK_0.001 761 Cervicalgia Both 282 4588 17 symptoms purple 4588, 282 1147, 62 1147, 75 1147, 73 1147, 72 0.0327 0.0615 0.595 0.2256 1.03 0.916 1.17 0.18 0.175 0.304 0.5169 1.2 0.85 1.69 0.141 0.176 0.424 0.3723 1.15 0.815 1.63 0.106 0.177 0.549 0.2606 1.11 0.786 1.57 PRS_PLINK_0.001 764 Sciatica Both 435 6052 17 symptoms purple 6052, 435 1513, 105 1513, 117 1513, 95 1513, 118 0.0248 0.0495 0.616 0.2104 1.03 0.93 1.13 0.101 0.138 0.464 0.3339 1.11 0.844 1.45 -0.0846 0.145 0.561 0.2513 0.919 0.691 1.22 0.129 0.139 0.354 0.4506 1.14 0.866 1.49 PRS_PLINK_0.001 766 Neuralgia, neuritis, and radiculitis NOS Both 197 3005 17 symptoms purple 3005, 197 752, 55 751, 43 751, 50 751, 49 -0.0452 0.0739 0.541 0.2671 0.956 0.827 1.1 -0.265 0.208 0.202 0.6947 0.767 0.51 1.15 -0.152 0.201 0.452 0.3453 0.859 0.579 1.28 -0.15 0.203 0.46 0.3368 0.861 0.578 1.28 PRS_PLINK_0.001 770 Myalgia and myositis unspecified Both 99 1565 17 symptoms purple 1565, 99 392, 27 391, 27 391, 24 391, 21 -0.076 0.101 0.452 0.3448 0.927 0.76 1.13 0.031 0.277 0.911 0.04043 1.03 0.599 1.78 -0.0529 0.284 0.853 0.06929 0.949 0.543 1.66 -0.29 0.294 0.323 0.4905 0.748 0.421 1.33 PRS_PLINK_0.001 771 Musculoskeletal symptoms referable to limbs Both 181 2216 17 symptoms purple 2216, 181 554, 37 554, 55 554, 33 554, 56 0.0802 0.0771 0.298 0.5253 1.08 0.932 1.26 0.371 0.219 0.0897 1.047 1.45 0.944 2.22 -0.128 0.243 0.6 0.2219 0.88 0.546 1.42 0.381 0.221 0.0845 1.073 1.46 0.949 2.25 PRS_PLINK_0.001 771.1 Swelling of limb Both 749 11658 17 symptoms purple 11658, 749 2915, 189 2914, 182 2914, 191 2915, 187 0.0136 0.0377 0.719 0.1435 1.01 0.941 1.09 -0.0323 0.107 0.763 0.1177 0.968 0.785 1.19 0.0248 0.106 0.815 0.08908 1.03 0.833 1.26 -0.014 0.106 0.896 0.04781 0.986 0.8 1.22 PRS_PLINK_0.001 772 Symptoms of the muscles Both 96 1628 17 symptoms purple 1628, 96 407, 23 407, 23 407, 34 407, 16 0.0136 0.104 0.896 0.04757 1.01 0.827 1.24 0.0523 0.295 0.859 0.06597 1.05 0.591 1.88 0.406 0.274 0.138 0.8601 1.5 0.878 2.57 -0.19 0.328 0.562 0.2501 0.827 0.434 1.57 PRS_PLINK_0.001 773 Pain in limb Both 1056 15834 17 symptoms purple 15834, 1056 3958, 266 3958, 252 3958, 261 3959, 277 0.0289 0.0321 0.367 0.4356 1.03 0.967 1.1 -0.0529 0.0906 0.559 0.2526 0.948 0.794 1.13 -0.00813 0.09 0.928 0.03243 0.992 0.831 1.18 0.0463 0.089 0.603 0.2197 1.05 0.88 1.25 PRS_PLINK_0.001 780 Hypothermia/Chills Both 16 428 17 symptoms purple 428, 16 107, 2 107, 2 107, 5 107, 7 0.535 0.261 0.0405 1.393 1.71 1.02 2.85 0.148 0.755 0.845 0.07322 1.16 0.264 5.09 0.668 0.698 0.338 0.4709 1.95 0.497 7.66 1.35 0.716 0.06 1.222 3.85 0.945 15.7 PRS_PLINK_0.001 781 Symptoms involving nervous and musculoskeletal systems Both 282 4758 17 symptoms purple 4758, 282 1190, 78 1189, 80 1189, 59 1190, 65 -0.0998 0.0599 0.0961 1.017 0.905 0.805 1.02 0.0233 0.163 0.887 0.05225 1.02 0.743 1.41 -0.274 0.176 0.119 0.9247 0.76 0.539 1.07 -0.2 0.173 0.246 0.6092 0.818 0.584 1.15 PRS_PLINK_0.001 782.3 Edema Both 148 4098 17 symptoms purple 4098, 148 1025, 27 1024, 35 1024, 48 1025, 38 0.162 0.0839 0.0533 1.273 1.18 0.998 1.39 0.253 0.253 0.318 0.4979 1.29 0.784 2.11 0.557 0.239 0.0201 1.697 1.74 1.09 2.79 0.343 0.249 0.169 0.7713 1.41 0.864 2.3 PRS_PLINK_0.001 782.6 Pallor and flushing Both 27 431 17 symptoms purple 431, 27 108, 6 108, 6 107, 5 108, 10 0.182 0.197 0.355 0.4499 1.2 0.816 1.76 0.0913 0.536 0.865 0.06311 1.1 0.383 3.13 -0.0543 0.584 0.926 0.03341 0.947 0.302 2.97 0.358 0.509 0.482 0.3171 1.43 0.528 3.88 PRS_PLINK_0.001 783 Fever of unknown origin Both 651 10025 17 symptoms purple 10025, 651 2506, 168 2506, 179 2506, 148 2506, 156 -0.0161 0.0406 0.691 0.1605 0.984 0.909 1.07 0.0598 0.111 0.589 0.2296 1.06 0.854 1.32 -0.14 0.116 0.228 0.6417 0.869 0.692 1.09 -0.0927 0.115 0.421 0.3761 0.911 0.727 1.14 PRS_PLINK_0.001 785 Abdominal pain Both 8153 79337 17 symptoms purple 79337, 8153 19834, 1957 19834, 2098 19834, 2004 19834, 2094 0.00484 0.0117 0.679 0.1679 1 0.982 1.03 0.0602 0.0331 0.069 1.161 1.06 0.995 1.13 0.00224 0.0335 0.947 0.02382 1 0.939 1.07 0.0386 0.0333 0.246 0.6098 1.04 0.974 1.11 PRS_PLINK_0.001 788 Syncope and collapse Both 1561 22542 17 symptoms purple 22542, 1561 5636, 402 5635, 397 5635, 365 5636, 397 -0.0146 0.0262 0.577 0.2385 0.986 0.936 1.04 -0.011 0.0732 0.88 0.05545 0.989 0.857 1.14 -0.0891 0.0748 0.234 0.6314 0.915 0.79 1.06 -0.0051 0.0735 0.945 0.02473 0.995 0.862 1.15 PRS_PLINK_0.001 789 Nausea and vomiting Both 1740 29399 17 symptoms purple 29399, 1740 7349, 432 7350, 443 7349, 435 7350, 430 -0.00634 0.0248 0.799 0.09772 0.994 0.946 1.04 0.0225 0.0696 0.746 0.127 1.02 0.892 1.17 0.00486 0.07 0.945 0.02475 1 0.876 1.15 -0.0169 0.0704 0.811 0.09122 0.983 0.857 1.13 PRS_PLINK_0.001 790 Nonspecific findings on examination of blood Both 22 363 17 symptoms purple 363, 22 91, 5 91, 4 90, 9 91, 4 0.0393 0.243 0.871 0.05982 1.04 0.646 1.67 -0.254 0.62 0.682 0.166 0.776 0.23 2.62 0.45 0.549 0.412 0.3852 1.57 0.535 4.6 -0.256 0.606 0.673 0.1721 0.774 0.236 2.54 PRS_PLINK_0.001 790.1 Elevated sedimentation rate Both 12 225 17 symptoms purple 225, 12 57, 3 56, 1 56, 7 56, 1 0.0395 0.282 0.888 0.05137 1.04 0.599 1.81 -0.639 0.892 0.473 0.3249 0.528 0.0919 3.03 1.02 0.697 0.144 0.8428 2.77 0.707 10.9 -0.754 0.841 0.37 0.4317 0.47 0.0905 2.45 PRS_PLINK_0.001 790.6 Other abnormal blood chemistry Both 1275 15922 17 symptoms purple 15922, 1275 3981, 351 3980, 303 3980, 294 3981, 327 -0.0353 0.029 0.225 0.6486 0.965 0.912 1.02 -0.138 0.0815 0.0908 1.042 0.871 0.743 1.02 -0.156 0.0822 0.0576 1.24 0.855 0.728 1.01 -0.0558 0.0803 0.488 0.3119 0.946 0.808 1.11 PRS_PLINK_0.001 791 Gangrene Both 59 1331 17 symptoms purple 1331, 59 332, 11 333, 16 332, 15 333, 17 0.102 0.13 0.433 0.364 1.11 0.858 1.43 0.371 0.375 0.322 0.4919 1.45 0.695 3.02 0.389 0.385 0.312 0.5056 1.48 0.694 3.14 0.472 0.378 0.211 0.6753 1.6 0.765 3.36 PRS_PLINK_0.001 792 Abnormal Papanicolaou smear of cervix and cervical HPV Female 16 230 17 symptoms purple 230, 16 58, 4 57, 4 57, 4 58, 4 -0.161 0.242 0.507 0.2951 0.851 0.529 1.37 0.199 0.703 0.777 0.1095 1.22 0.307 4.84 0.228 0.708 0.748 0.1263 1.26 0.313 5.03 -0.000167 0.643 1 8.994e-05 1 0.283 3.53 PRS_PLINK_0.001 793 Nonspecific abnormal findings on radiological and other examination of musculoskeletal system Both 19 351 17 symptoms purple 351, 19 88, 4 88, 5 87, 6 88, 4 0.13 0.232 0.574 0.2413 1.14 0.723 1.79 0.262 0.604 0.664 0.1776 1.3 0.398 4.24 0.385 0.585 0.51 0.2925 1.47 0.467 4.63 0.00441 0.626 0.994 0.002446 1 0.294 3.43 PRS_PLINK_0.001 793.2 Nonspecific abnormal findings on radiological and other examination of other intrathoracic organs (echocardiogram, etc) Both 109 1383 17 symptoms purple 1383, 109 346, 28 346, 27 345, 29 346, 25 0.00844 0.1 0.933 0.03023 1.01 0.829 1.23 -0.0361 0.274 0.895 0.04807 0.965 0.564 1.65 0.0831 0.271 0.76 0.1195 1.09 0.638 1.85 -0.0312 0.282 0.912 0.04003 0.969 0.558 1.68 PRS_PLINK_0.001 794 Abnormal results of other function studies (bladder, pancreas, placenta, spleen, etc) Both 45 328 17 symptoms purple 328, 45 82, 12 82, 10 82, 13 82, 10 -0.185 0.173 0.286 0.5441 0.831 0.592 1.17 -0.174 0.444 0.696 0.1576 0.841 0.352 2.01 0.0819 0.439 0.852 0.06952 1.09 0.459 2.57 -0.179 0.456 0.695 0.1581 0.836 0.342 2.05 PRS_PLINK_0.001 797 Shock Both 11 391 17 symptoms purple 391, 11 98, 0 98, 4 97, 3 98, 4 0.535 0.288 0.0633 1.199 1.71 0.971 3 2.03 1.21 0.0927 1.033 7.62 0.714 81.2 1.86 1.08 0.086 1.065 6.4 0.769 53.3 1.98 1.15 0.0834 1.079 7.27 0.77 68.6 PRS_PLINK_0.001 797.1 Cardiogenic shock Both 3 255 17 symptoms purple 255, 3 64, 0 64, 0 63, 1 64, 2 1.28 0.514 0.0129 1.89 3.59 1.31 9.84 0.0397 1.08 0.971 0.01298 1.04 0.126 8.56 0.986 1.05 0.347 0.4594 2.68 0.343 21 1.77 1.17 0.132 0.8804 5.87 0.588 58.6 PRS_PLINK_0.001 798 Malaise and fatigue Both 527 8785 17 symptoms purple 8785, 527 2197, 133 2196, 136 2196, 136 2196, 122 -0.0541 0.0444 0.223 0.6516 0.947 0.868 1.03 0.0332 0.125 0.791 0.102 1.03 0.809 1.32 0.0382 0.125 0.76 0.119 1.04 0.813 1.33 -0.0636 0.129 0.622 0.2063 0.938 0.729 1.21 PRS_PLINK_0.001 798.1 Chronic fatigue syndrome Both 117 1671 17 symptoms purple 1671, 117 418, 35 418, 20 417, 37 418, 25 -0.113 0.0913 0.218 0.6621 0.894 0.747 1.07 -0.54 0.28 0.054 1.268 0.583 0.336 1.01 0.0736 0.242 0.761 0.1186 1.08 0.67 1.73 -0.279 0.267 0.296 0.5285 0.757 0.449 1.28 PRS_PLINK_0.001 800 Fracture of lower limb Both 1422 17634 18 injuries & poisonings gray50 17634, 1422 4409, 343 4408, 349 4408, 351 4409, 379 0.0316 0.0278 0.254 0.5944 1.03 0.977 1.09 0.0201 0.0789 0.799 0.09764 1.02 0.874 1.19 0.0278 0.079 0.725 0.1399 1.03 0.881 1.2 0.109 0.0778 0.16 0.7952 1.12 0.958 1.3 PRS_PLINK_0.001 800.1 Fracture of neck of femur Both 329 4441 18 injuries & poisonings gray50 4441, 329 1111, 75 1110, 85 1110, 97 1110, 72 0.0255 0.0569 0.654 0.1844 1.03 0.918 1.15 0.158 0.163 0.333 0.4769 1.17 0.85 1.61 0.279 0.159 0.0793 1.1 1.32 0.968 1.8 -0.000426 0.17 0.998 0.0008684 1 0.716 1.4 PRS_PLINK_0.001 800.2 Fracture of unspecified part of femur Both 24 399 18 injuries & poisonings gray50 399, 24 100, 6 100, 6 99, 5 100, 7 -0.0685 0.192 0.721 0.1423 0.934 0.641 1.36 -0.0643 0.556 0.908 0.04191 0.938 0.315 2.79 -0.316 0.577 0.584 0.2334 0.729 0.235 2.26 0.0631 0.552 0.909 0.04144 1.07 0.361 3.15 PRS_PLINK_0.001 800.3 Fracture of tibia and fibula Both 468 5497 18 injuries & poisonings gray50 5497, 468 1375, 107 1374, 116 1374, 116 1374, 129 0.0513 0.0483 0.288 0.5409 1.05 0.958 1.16 0.0635 0.139 0.648 0.1886 1.07 0.812 1.4 0.0848 0.139 0.542 0.266 1.09 0.829 1.43 0.178 0.137 0.193 0.7141 1.19 0.914 1.56 PRS_PLINK_0.001 800.4 Fracture of patella Both 163 1946 18 injuries & poisonings gray50 1946, 163 487, 32 486, 37 486, 49 487, 45 0.134 0.0821 0.102 0.992 1.14 0.974 1.34 0.133 0.245 0.589 0.23 1.14 0.706 1.85 0.399 0.233 0.0868 1.062 1.49 0.944 2.35 0.35 0.238 0.141 0.8522 1.42 0.891 2.26 PRS_PLINK_0.001 801 Fracture of ankle and foot Both 506 5615 18 injuries & poisonings gray50 5615, 506 1404, 107 1404, 136 1403, 131 1404, 132 0.0505 0.0464 0.277 0.5573 1.05 0.96 1.15 0.238 0.134 0.0761 1.119 1.27 0.975 1.65 0.219 0.136 0.106 0.9737 1.24 0.954 1.62 0.212 0.135 0.117 0.931 1.24 0.948 1.61 PRS_PLINK_0.001 801.1 Fracture of foot Both 439 4704 18 injuries & poisonings gray50 4704, 439 1176, 100 1176, 111 1176, 118 1176, 110 0.0181 0.05 0.718 0.1441 1.02 0.923 1.12 0.111 0.143 0.438 0.3585 1.12 0.844 1.48 0.192 0.142 0.177 0.7528 1.21 0.917 1.6 0.103 0.144 0.472 0.3259 1.11 0.836 1.47 PRS_PLINK_0.001 802 Fracture of pelvis Both 151 1882 18 injuries & poisonings gray50 1882, 151 471, 38 470, 33 470, 36 471, 44 0.0733 0.0862 0.395 0.4031 1.08 0.909 1.27 -0.164 0.243 0.5 0.3007 0.849 0.527 1.37 -0.0411 0.239 0.863 0.0639 0.96 0.601 1.53 0.183 0.23 0.425 0.3717 1.2 0.766 1.88 PRS_PLINK_0.001 803 Fracture of upper limb Both 1818 20913 18 injuries & poisonings gray50 20913, 1818 5229, 430 5228, 470 5228, 423 5228, 495 0.0329 0.0246 0.181 0.7421 1.03 0.985 1.08 0.0931 0.0696 0.181 0.7428 1.1 0.958 1.26 0.000666 0.0714 0.993 0.003246 1 0.87 1.15 0.161 0.0691 0.0201 1.697 1.17 1.03 1.34 PRS_PLINK_0.001 803.1 Fracture of humerus Both 308 4192 18 injuries & poisonings gray50 4192, 308 1048, 77 1048, 91 1048, 67 1048, 73 -0.0368 0.0584 0.529 0.2765 0.964 0.86 1.08 0.19 0.161 0.238 0.624 1.21 0.882 1.66 -0.101 0.172 0.557 0.2538 0.904 0.645 1.27 -0.0142 0.169 0.933 0.03015 0.986 0.709 1.37 PRS_PLINK_0.001 803.2 Fracture of radius and ulna Both 1191 13196 18 injuries & poisonings gray50 13196, 1191 3299, 286 3299, 304 3299, 275 3299, 326 0.0139 0.0304 0.647 0.1891 1.01 0.955 1.08 0.0621 0.0859 0.47 0.3284 1.06 0.899 1.26 -0.0265 0.0881 0.764 0.117 0.974 0.819 1.16 0.14 0.0851 0.101 0.9947 1.15 0.973 1.36 PRS_PLINK_0.001 803.3 Fracture of clavicle or scapula Both 344 3979 18 injuries & poisonings gray50 3979, 344 995, 82 995, 85 994, 68 995, 109 0.121 0.0562 0.0311 1.508 1.13 1.01 1.26 0.0479 0.16 0.765 0.1164 1.05 0.766 1.44 -0.17 0.169 0.313 0.5039 0.844 0.606 1.17 0.314 0.153 0.0393 1.405 1.37 1.02 1.85 PRS_PLINK_0.001 804 Fracture of hand or wrist Both 742 8448 18 injuries & poisonings gray50 8448, 742 2112, 182 2112, 186 2112, 185 2112, 189 0.00973 0.0388 0.802 0.09571 1.01 0.936 1.09 0.0234 0.108 0.829 0.08139 1.02 0.828 1.27 0.0267 0.109 0.806 0.0936 1.03 0.83 1.27 0.0348 0.108 0.748 0.1261 1.04 0.837 1.28 PRS_PLINK_0.001 805 Fracture of vertebral column without mention of spinal cord injury Both 236 3560 18 injuries & poisonings gray50 3560, 236 890, 66 890, 55 890, 46 890, 69 0.00901 0.0678 0.894 0.04853 1.01 0.883 1.15 -0.195 0.187 0.297 0.5268 0.823 0.57 1.19 -0.337 0.195 0.0846 1.073 0.714 0.487 1.05 0.0862 0.178 0.628 0.2024 1.09 0.769 1.54 PRS_PLINK_0.001 807 Fracture of ribs Both 156 1968 18 injuries & poisonings gray50 1968, 156 492, 30 492, 43 492, 46 492, 37 0.0674 0.0831 0.417 0.3796 1.07 0.909 1.26 0.383 0.242 0.114 0.9437 1.47 0.912 2.36 0.441 0.24 0.066 1.18 1.55 0.971 2.49 0.245 0.249 0.326 0.4863 1.28 0.783 2.08 PRS_PLINK_0.001 809 Fracture of unspecified bones Both 256 3335 18 injuries & poisonings gray50 3335, 256 834, 73 834, 65 833, 54 834, 64 -0.0784 0.0648 0.226 0.646 0.925 0.814 1.05 -0.114 0.176 0.518 0.2857 0.892 0.632 1.26 -0.274 0.185 0.138 0.859 0.76 0.529 1.09 -0.107 0.178 0.546 0.2626 0.898 0.634 1.27 PRS_PLINK_0.001 817 Concussion Both 63 593 18 injuries & poisonings gray50 593, 63 149, 18 148, 8 148, 19 148, 18 0.082 0.127 0.519 0.2849 1.09 0.846 1.39 -0.808 0.43 0.0603 1.219 0.446 0.192 1.04 0.133 0.342 0.696 0.1573 1.14 0.585 2.23 0.0578 0.345 0.867 0.06208 1.06 0.539 2.08 PRS_PLINK_0.001 818 Intracranial hemorrhage (injury) Both 66 1256 18 injuries & poisonings gray50 1256, 66 314, 17 314, 16 314, 13 314, 20 0.0478 0.123 0.698 0.1562 1.05 0.824 1.34 -0.0818 0.342 0.811 0.09115 0.921 0.472 1.8 -0.178 0.364 0.624 0.2047 0.837 0.41 1.71 0.163 0.326 0.617 0.2101 1.18 0.622 2.23 PRS_PLINK_0.001 819 Skull and face fracture and other intercranial injury Both 505 7248 18 injuries & poisonings gray50 7248, 505 1812, 116 1812, 119 1812, 118 1812, 152 0.158 0.0465 0.000661 3.18 1.17 1.07 1.28 0.0535 0.134 0.691 0.1607 1.05 0.811 1.37 0.0226 0.135 0.867 0.06192 1.02 0.785 1.33 0.274 0.128 0.0322 1.493 1.31 1.02 1.69 PRS_PLINK_0.001 823 Torus fracture Both 377 4275 18 injuries & poisonings gray50 4275, 377 1069, 83 1069, 96 1068, 93 1069, 105 0.0572 0.0532 0.283 0.5486 1.06 0.954 1.18 0.127 0.155 0.413 0.3845 1.14 0.838 1.54 0.106 0.156 0.499 0.3016 1.11 0.818 1.51 0.243 0.154 0.114 0.9423 1.27 0.943 1.72 PRS_PLINK_0.001 830 Dislocation Both 443 5155 18 injuries & poisonings gray50 5155, 443 1289, 95 1289, 116 1288, 125 1289, 107 0.0534 0.05 0.285 0.5453 1.05 0.956 1.16 0.195 0.143 0.172 0.7644 1.22 0.919 1.61 0.284 0.142 0.0453 1.344 1.33 1.01 1.75 0.121 0.146 0.408 0.3895 1.13 0.848 1.5 PRS_PLINK_0.001 835 Internal derangement of knee Both 3460 39215 18 injuries & poisonings gray50 39215, 3460 9804, 859 9804, 834 9803, 869 9804, 898 0.00752 0.0177 0.671 0.1731 1.01 0.973 1.04 -0.029 0.0507 0.567 0.2462 0.971 0.88 1.07 0.0122 0.0503 0.808 0.09232 1.01 0.917 1.12 0.0461 0.0501 0.357 0.4471 1.05 0.949 1.16 PRS_PLINK_0.001 836 Traumatic arthropathy Both 89 1413 18 injuries & poisonings gray50 1413, 89 354, 33 353, 15 353, 21 353, 20 -0.166 0.106 0.117 0.9304 0.847 0.688 1.04 -0.78 0.312 0.0126 1.901 0.458 0.249 0.846 -0.423 0.283 0.136 0.867 0.655 0.376 1.14 -0.486 0.287 0.0904 1.044 0.615 0.351 1.08 PRS_PLINK_0.001 840 Sprains and strains Both 106 1188 18 injuries & poisonings gray50 1188, 106 297, 18 297, 30 297, 36 297, 22 0.0257 0.0987 0.795 0.09977 1.03 0.846 1.24 0.467 0.303 0.123 0.9113 1.6 0.882 2.89 0.687 0.293 0.0189 1.723 1.99 1.12 3.53 0.164 0.319 0.608 0.2161 1.18 0.63 2.2 PRS_PLINK_0.001 850 Hemorrhage or hematoma complicating a procedure Both 979 13517 18 injuries & poisonings gray50 13517, 979 3380, 255 3379, 226 3379, 234 3379, 264 0.00967 0.0334 0.772 0.1125 1.01 0.946 1.08 -0.113 0.0944 0.233 0.6329 0.894 0.743 1.08 -0.0813 0.0937 0.386 0.4139 0.922 0.767 1.11 0.0543 0.0914 0.552 0.2579 1.06 0.883 1.26 PRS_PLINK_0.001 851 Complications of transplants and reattached limbs Both 19 419 18 injuries & poisonings gray50 419, 19 105, 7 105, 4 104, 2 105, 6 0.00271 0.233 0.991 0.004039 1 0.635 1.58 -0.67 0.586 0.253 0.5969 0.512 0.162 1.61 -1.37 0.704 0.0523 1.281 0.255 0.0642 1.01 -0.224 0.548 0.682 0.1662 0.799 0.273 2.34 PRS_PLINK_0.001 853 Complication of colostomy or enterostomy Both 68 1353 18 injuries & poisonings gray50 1353, 68 339, 13 338, 22 338, 18 338, 15 -0.00156 0.124 0.99 0.004378 0.998 0.783 1.27 0.452 0.344 0.189 0.7227 1.57 0.8 3.09 0.288 0.354 0.416 0.3813 1.33 0.667 2.67 0.133 0.37 0.72 0.1429 1.14 0.553 2.36 PRS_PLINK_0.001 854 Complications of cardiac/vascular device, implant, and graft Both 233 4551 18 injuries & poisonings gray50 4551, 233 1138, 69 1138, 54 1137, 54 1138, 56 -0.0382 0.0659 0.562 0.2502 0.963 0.846 1.1 -0.241 0.184 0.191 0.7192 0.786 0.548 1.13 -0.235 0.184 0.203 0.6929 0.791 0.551 1.13 -0.194 0.183 0.289 0.5394 0.823 0.575 1.18 PRS_PLINK_0.001 857 Mechanical complication of unspecified genitourinary device, implant, and graft Both 237 3304 18 injuries & poisonings gray50 3304, 237 826, 71 826, 60 826, 46 826, 60 -0.0545 0.0683 0.424 0.3722 0.947 0.828 1.08 -0.158 0.18 0.382 0.4177 0.854 0.6 1.22 -0.445 0.194 0.0217 1.664 0.641 0.438 0.937 -0.168 0.182 0.356 0.4491 0.845 0.592 1.21 PRS_PLINK_0.001 858 Complication of internal orthopedic device Both 611 7863 18 injuries & poisonings gray50 7863, 611 1966, 155 1966, 155 1965, 135 1966, 166 0.0113 0.042 0.788 0.1034 1.01 0.931 1.1 0.0108 0.118 0.927 0.03285 1.01 0.802 1.27 -0.124 0.122 0.309 0.5105 0.883 0.695 1.12 0.0555 0.117 0.634 0.1977 1.06 0.841 1.33 PRS_PLINK_0.001 859 Complication due to other implant and internal device Both 533 8246 18 injuries & poisonings gray50 8246, 533 2062, 139 2061, 143 2061, 114 2062, 137 -0.00708 0.0452 0.876 0.05769 0.993 0.909 1.08 0.0275 0.123 0.823 0.08482 1.03 0.808 1.31 -0.201 0.13 0.121 0.9163 0.818 0.634 1.05 -0.0106 0.125 0.932 0.03041 0.989 0.775 1.26 PRS_PLINK_0.001 860 Bone marrow or stem cell transplant Both 10 174 2 neoplasms darkcyan 174, 10 44, 4 43, 1 43, 2 44, 3 -0.104 0.283 0.714 0.1465 0.901 0.517 1.57 -1.21 0.976 0.214 0.6694 0.298 0.044 2.01 -0.243 0.83 0.77 0.1137 0.784 0.154 3.99 -0.223 0.693 0.748 0.1261 0.8 0.206 3.11 PRS_PLINK_0.001 870 Open wounds of head; neck; and trunk Both 512 8680 18 injuries & poisonings gray50 8680, 512 2170, 111 2170, 128 2170, 126 2170, 147 0.0868 0.0453 0.0551 1.259 1.09 0.998 1.19 0.154 0.133 0.246 0.6099 1.17 0.899 1.51 0.129 0.133 0.331 0.4795 1.14 0.877 1.48 0.292 0.129 0.0241 1.619 1.34 1.04 1.73 PRS_PLINK_0.001 870.1 Open wound or laceration of eye or eyelid Both 37 684 18 injuries & poisonings gray50 684, 37 171, 8 171, 10 171, 7 171, 12 0.136 0.164 0.407 0.3906 1.15 0.831 1.58 0.131 0.45 0.771 0.1129 1.14 0.472 2.75 -0.0715 0.482 0.882 0.05455 0.931 0.362 2.39 0.547 0.458 0.232 0.6339 1.73 0.704 4.24 PRS_PLINK_0.001 870.2 Open wound of ear Both 27 483 18 injuries & poisonings gray50 483, 27 121, 4 121, 10 120, 7 121, 6 0.16 0.198 0.419 0.3778 1.17 0.796 1.73 0.832 0.544 0.126 0.9 2.3 0.792 6.67 0.542 0.579 0.35 0.4561 1.72 0.552 5.35 0.37 0.591 0.531 0.2748 1.45 0.454 4.62 PRS_PLINK_0.001 870.3 Other open wound of head and face Both 427 7159 18 injuries & poisonings gray50 7159, 427 1790, 90 1790, 102 1789, 115 1790, 120 0.0988 0.0498 0.0471 1.327 1.1 1 1.22 0.129 0.148 0.383 0.4169 1.14 0.852 1.52 0.248 0.144 0.085 1.07 1.28 0.966 1.7 0.314 0.144 0.0287 1.542 1.37 1.03 1.81 PRS_PLINK_0.001 870.4 Open wound of nose and sinus Both 34 530 18 injuries & poisonings gray50 530, 34 133, 11 132, 9 132, 7 133, 7 -0.119 0.175 0.499 0.3021 0.888 0.63 1.25 -0.402 0.453 0.374 0.4266 0.669 0.275 1.62 -0.635 0.48 0.186 0.73 0.53 0.207 1.36 -0.712 0.489 0.145 0.8387 0.49 0.188 1.28 PRS_PLINK_0.001 870.6 Open wound of neck Both 11 155 18 injuries & poisonings gray50 155, 11 39, 1 39, 5 38, 1 39, 4 0.182 0.269 0.497 0.3033 1.2 0.709 2.03 1.2 0.833 0.148 0.829 3.33 0.652 17 0.344 0.942 0.715 0.1455 1.41 0.222 8.94 1.29 0.905 0.153 0.8164 3.65 0.619 21.5 PRS_PLINK_0.001 871 Open wounds of extremities Both 785 10354 18 injuries & poisonings gray50 10354, 785 2588, 161 2588, 203 2588, 203 2589, 218 0.0883 0.0371 0.0174 1.759 1.09 1.02 1.17 0.223 0.109 0.04 1.398 1.25 1.01 1.55 0.237 0.109 0.0296 1.529 1.27 1.02 1.57 0.308 0.108 0.00418 2.378 1.36 1.1 1.68 PRS_PLINK_0.001 871.1 Open wound of hand except finger(s) Both 6 116 18 injuries & poisonings gray50 116, 6 29, 1 29, 3 29, 1 29, 1 -0.162 0.385 0.673 0.1717 0.85 0.4 1.81 0.624 0.881 0.479 0.32 1.87 0.332 10.5 1.87 1.58 0.237 0.625 6.51 0.291 146 0.0171 1.07 0.987 0.005596 1.02 0.125 8.25 PRS_PLINK_0.001 871.2 Open wound of finger(s) Both 11 226 18 injuries & poisonings gray50 226, 11 57, 4 56, 1 56, 5 57, 1 -0.288 0.272 0.289 0.5392 0.75 0.44 1.28 -1.15 0.879 0.189 0.7226 0.316 0.0564 1.77 0.531 0.657 0.419 0.3778 1.7 0.469 6.16 -1.12 0.818 0.17 0.7697 0.326 0.0656 1.62 PRS_PLINK_0.001 871.3 Open wound of foot except toe(s) alone Both 36 417 18 injuries & poisonings gray50 417, 36 105, 11 104, 2 104, 8 104, 15 0.191 0.168 0.256 0.5921 1.21 0.87 1.68 -1.44 0.653 0.0276 1.559 0.237 0.0659 0.853 -0.248 0.47 0.598 0.2234 0.781 0.311 1.96 0.274 0.414 0.508 0.2937 1.32 0.584 2.96 PRS_PLINK_0.001 872 Traumatic amputation Both 91 1187 18 injuries & poisonings gray50 1187, 91 297, 19 297, 29 296, 17 297, 26 -0.0186 0.107 0.862 0.06437 0.982 0.796 1.21 0.39 0.301 0.196 0.7088 1.48 0.818 2.67 -0.129 0.335 0.7 0.1547 0.879 0.456 1.69 0.275 0.305 0.367 0.4349 1.32 0.724 2.4 PRS_PLINK_0.001 873 Broken tooth Both 56 590 18 injuries & poisonings gray50 590, 56 148, 17 147, 15 147, 15 148, 9 -0.264 0.144 0.067 1.174 0.768 0.579 1.02 -0.151 0.365 0.678 0.1685 0.86 0.42 1.76 -0.116 0.374 0.756 0.1215 0.89 0.428 1.85 -0.562 0.413 0.174 0.76 0.57 0.253 1.28 PRS_PLINK_0.001 874 Complication of amputation stump Both 15 435 18 injuries & poisonings gray50 435, 15 109, 5 109, 7 108, 3 109, 0 -0.504 0.227 0.0264 1.578 0.604 0.387 0.943 0.367 0.542 0.498 0.3031 1.44 0.499 4.17 -0.398 0.631 0.529 0.2769 0.672 0.195 2.31 -2.74 1.3 0.0345 1.462 0.0646 0.00509 0.819 PRS_PLINK_0.001 905 Late effects of musculoskeletal and connective tissue injuries Both 26 409 18 injuries & poisonings gray50 409, 26 103, 3 102, 12 102, 5 102, 6 0.0417 0.194 0.829 0.08129 1.04 0.714 1.52 1.17 0.582 0.045 1.347 3.21 1.03 10 0.26 0.647 0.688 0.1624 1.3 0.365 4.6 0.476 0.621 0.443 0.3537 1.61 0.477 5.43 PRS_PLINK_0.001 907 Injuries to the nervous system Both 270 3320 18 injuries & poisonings gray50 3320, 270 830, 68 830, 61 830, 82 830, 59 0.0072 0.0634 0.91 0.04119 1.01 0.89 1.14 -0.103 0.181 0.569 0.245 0.902 0.632 1.29 0.194 0.17 0.256 0.5918 1.21 0.869 1.69 -0.144 0.183 0.431 0.3655 0.866 0.604 1.24 PRS_PLINK_0.001 915 Superficial injury without mention of infection Both 662 10580 18 injuries & poisonings gray50 10580, 662 2645, 139 2645, 181 2645, 158 2645, 184 0.0847 0.0401 0.0344 1.464 1.09 1.01 1.18 0.268 0.116 0.0205 1.689 1.31 1.04 1.64 0.141 0.119 0.237 0.6251 1.15 0.911 1.45 0.299 0.116 0.00987 2.006 1.35 1.07 1.69 PRS_PLINK_0.001 916 Contusion Both 220 3503 18 injuries & poisonings gray50 3503, 220 876, 50 876, 66 875, 50 876, 54 -0.0141 0.0687 0.838 0.0768 0.986 0.862 1.13 0.287 0.191 0.133 0.8766 1.33 0.916 1.94 -0.0112 0.204 0.956 0.01941 0.989 0.664 1.47 0.0996 0.2 0.619 0.2086 1.1 0.746 1.64 PRS_PLINK_0.001 930 Allergic reaction to food Both 36 461 18 injuries & poisonings gray50 461, 36 116, 9 115, 9 115, 8 115, 10 0.118 0.177 0.505 0.2967 1.13 0.795 1.59 0.0633 0.468 0.892 0.04946 1.07 0.426 2.67 0.0131 0.474 0.978 0.009677 1.01 0.4 2.56 0.116 0.46 0.801 0.09616 1.12 0.456 2.77 PRS_PLINK_0.001 938 Dermatitis due to solar radiation Both 94 930 18 injuries & poisonings gray50 930, 94 233, 19 232, 21 232, 30 233, 24 0.0547 0.105 0.601 0.221 1.06 0.86 1.3 0.104 0.326 0.748 0.1259 1.11 0.586 2.1 0.489 0.31 0.115 0.9393 1.63 0.888 3 0.186 0.317 0.558 0.2537 1.2 0.647 2.24 PRS_PLINK_0.001 938.2 Chronic dermatitis due to solar radiation Both 70 580 18 injuries & poisonings gray50 580, 70 145, 18 145, 15 145, 21 145, 16 -0.0604 0.127 0.635 0.1972 0.941 0.734 1.21 -0.213 0.369 0.564 0.2489 0.808 0.392 1.67 0.144 0.34 0.672 0.1724 1.15 0.593 2.25 -0.0925 0.359 0.797 0.09873 0.912 0.451 1.84 PRS_PLINK_0.001 939 Atopic/contact dermatitis due to other or unspecified Both 415 5310 13 dermatologic firebrick 5310, 415 1328, 100 1327, 103 1327, 86 1328, 126 0.0708 0.0503 0.159 0.7984 1.07 0.973 1.18 0.0379 0.145 0.793 0.1005 1.04 0.782 1.38 -0.128 0.152 0.397 0.401 0.88 0.653 1.18 0.201 0.14 0.151 0.8204 1.22 0.929 1.61 PRS_PLINK_0.001 941 Adverse reaction to serum or vaccine Both 45 568 18 injuries & poisonings gray50 568, 45 142, 9 142, 8 142, 12 142, 16 0.275 0.141 0.0521 1.284 1.32 0.998 1.74 -0.126 0.472 0.79 0.1023 0.882 0.35 2.23 0.167 0.439 0.704 0.1527 1.18 0.5 2.8 0.492 0.416 0.238 0.6238 1.63 0.723 3.7 PRS_PLINK_0.001 942 Infusion and transfusion reaction Both 10 249 18 injuries & poisonings gray50 249, 10 63, 2 62, 3 62, 1 62, 4 0.158 0.27 0.56 0.2521 1.17 0.689 1.99 0.557 0.873 0.523 0.2812 1.75 0.316 9.66 -0.553 0.923 0.549 0.2603 0.575 0.0943 3.51 0.542 0.743 0.465 0.3322 1.72 0.401 7.38 PRS_PLINK_0.001 946 Anaphylactic shock NOS Both 115 1379 18 injuries & poisonings gray50 1379, 115 345, 24 345, 37 344, 26 345, 28 0.0819 0.0968 0.397 0.4007 1.09 0.898 1.31 0.434 0.266 0.103 0.987 1.54 0.916 2.6 0.079 0.287 0.783 0.1062 1.08 0.617 1.9 0.153 0.285 0.591 0.2286 1.17 0.667 2.04 PRS_PLINK_0.001 947 Urticaria Both 72 995 18 injuries & poisonings gray50 995, 72 249, 23 249, 13 248, 16 249, 20 -0.0946 0.114 0.408 0.3897 0.91 0.727 1.14 -0.569 0.347 0.101 0.9939 0.566 0.287 1.12 -0.326 0.332 0.325 0.4881 0.722 0.377 1.38 -0.135 0.311 0.665 0.1771 0.874 0.475 1.61 PRS_PLINK_0.001 949 Allergies, other Both 82 1052 18 injuries & poisonings gray50 1052, 82 263, 13 263, 26 263, 20 263, 23 0.103 0.114 0.365 0.4376 1.11 0.887 1.39 0.685 0.339 0.0435 1.362 1.98 1.02 3.85 0.406 0.352 0.249 0.6037 1.5 0.753 2.99 0.486 0.346 0.16 0.7969 1.63 0.826 3.2 PRS_PLINK_0.001 952 Spinal cord injury without evidence of spinal bone injury Both 81 1089 18 injuries & poisonings gray50 1089, 81 273, 25 272, 20 272, 14 272, 22 -0.103 0.112 0.357 0.4478 0.902 0.724 1.12 -0.223 0.306 0.467 0.3305 0.8 0.439 1.46 -0.541 0.334 0.105 0.9795 0.582 0.302 1.12 -0.0687 0.298 0.818 0.0875 0.934 0.521 1.67 PRS_PLINK_0.001 957 Injury to other and unspecified nerves Both 47 656 18 injuries & poisonings gray50 656, 47 164, 13 164, 9 164, 16 164, 9 0.00944 0.144 0.948 0.02323 1.01 0.761 1.34 -0.379 0.421 0.368 0.4337 0.685 0.3 1.56 0.32 0.384 0.405 0.3926 1.38 0.649 2.92 -0.316 0.434 0.467 0.3304 0.729 0.311 1.71 PRS_PLINK_0.001 958 Certain early complications of trauma or procedure Both 66 1222 18 injuries & poisonings gray50 1222, 66 306, 20 305, 16 305, 13 306, 17 -0.0643 0.122 0.599 0.2225 0.938 0.738 1.19 -0.193 0.336 0.566 0.2474 0.825 0.427 1.59 -0.331 0.35 0.344 0.4637 0.718 0.361 1.43 -0.107 0.331 0.747 0.1269 0.899 0.47 1.72 PRS_PLINK_0.001 958.1 Postoperative shock Both 10 131 18 injuries & poisonings gray50 131, 10 33, 1 33, 2 32, 4 33, 3 0.285 0.319 0.371 0.4302 1.33 0.712 2.49 -1.42 1.43 0.321 0.4936 0.243 0.0148 3.98 1.67 0.975 0.0866 1.062 5.32 0.786 36 0.602 0.955 0.529 0.2767 1.82 0.281 11.9 PRS_PLINK_0.001 958.2 Traumatic and surgical subcutaneous emphysema Both 11 197 18 injuries & poisonings gray50 197, 11 50, 4 49, 4 49, 0 49, 3 -0.12 0.294 0.683 0.1657 0.887 0.498 1.58 0.204 0.673 0.761 0.1185 1.23 0.328 4.59 -1.94 1.11 0.0805 1.094 0.144 0.0165 1.26 0.0303 0.702 0.966 0.01523 1.03 0.261 4.08 PRS_PLINK_0.001 960 Poisoning by antibiotics Both 3803 47343 18 injuries & poisonings gray50 47343, 3803 11835, 949 11836, 968 11835, 926 11836, 960 -0.0114 0.0169 0.498 0.3028 0.989 0.956 1.02 0.0171 0.0475 0.719 0.143 1.02 0.927 1.12 -0.0221 0.0481 0.645 0.1902 0.978 0.89 1.07 0.0104 0.0478 0.828 0.08197 1.01 0.92 1.11 PRS_PLINK_0.001 960.2 Allergy/adverse effect of penicillin Both 3301 41458 18 injuries & poisonings gray50 41458, 3301 10365, 817 10364, 840 10364, 807 10365, 837 -0.0112 0.018 0.537 0.2703 0.989 0.955 1.02 0.0236 0.0511 0.644 0.1911 1.02 0.926 1.13 -0.00922 0.0516 0.858 0.06636 0.991 0.895 1.1 0.0239 0.0513 0.642 0.1927 1.02 0.926 1.13 PRS_PLINK_0.001 961 Poisoning by other anti-infectives Both 105 1054 18 injuries & poisonings gray50 1054, 105 264, 23 263, 31 263, 29 264, 22 -0.0583 0.103 0.57 0.244 0.943 0.772 1.15 0.239 0.284 0.401 0.3965 1.27 0.727 2.22 0.241 0.288 0.402 0.3956 1.27 0.724 2.24 -0.114 0.306 0.71 0.149 0.892 0.49 1.62 PRS_PLINK_0.001 961.1 Poisoning/allergy of sulfonamides Both 203 2332 18 injuries & poisonings gray50 2332, 203 583, 56 583, 51 583, 50 583, 46 -0.0907 0.0727 0.212 0.6736 0.913 0.792 1.05 -0.1 0.2 0.616 0.2105 0.905 0.611 1.34 -0.104 0.201 0.604 0.2188 0.901 0.607 1.34 -0.237 0.206 0.251 0.6011 0.789 0.527 1.18 PRS_PLINK_0.001 962 Poisoning by hormones and synthetic substitutes Both 53 935 18 injuries & poisonings gray50 935, 53 234, 14 234, 17 233, 9 234, 13 -0.148 0.143 0.3 0.5229 0.862 0.652 1.14 -0.0389 0.368 0.916 0.03821 0.962 0.468 1.98 -0.456 0.412 0.269 0.5708 0.634 0.283 1.42 -0.0976 0.379 0.797 0.09867 0.907 0.432 1.91 PRS_PLINK_0.001 962.3 Hormones and synthetic substitutes causing adverse effects in therapeutic use Both 53 902 18 injuries & poisonings gray50 902, 53 226, 13 225, 19 225, 8 226, 13 -0.134 0.142 0.345 0.4619 0.875 0.662 1.16 0.106 0.367 0.773 0.112 1.11 0.542 2.28 -0.465 0.431 0.281 0.5518 0.628 0.27 1.46 -0.00564 0.384 0.988 0.005114 0.994 0.468 2.11 PRS_PLINK_0.001 963 Poisoning by primarily systemic agents Both 27 563 18 injuries & poisonings gray50 563, 27 141, 5 141, 7 140, 12 141, 3 -0.0799 0.187 0.669 0.1749 0.923 0.64 1.33 0.341 0.534 0.523 0.2815 1.41 0.494 4 0.758 0.495 0.126 0.8999 2.13 0.808 5.63 -0.346 0.616 0.574 0.2409 0.707 0.212 2.37 PRS_PLINK_0.001 964 Poisoning by agents primarily affecting blood constituents Both 38 728 18 injuries & poisonings gray50 728, 38 182, 11 182, 10 182, 5 182, 12 0.0677 0.161 0.675 0.1709 1.07 0.78 1.47 0.0529 0.446 0.906 0.04303 1.05 0.44 2.53 -0.289 0.531 0.587 0.2317 0.749 0.265 2.12 0.188 0.417 0.653 0.1854 1.21 0.533 2.73 PRS_PLINK_0.001 964.1 Anticoagulants causing adverse effects Both 37 709 18 injuries & poisonings gray50 709, 37 178, 11 177, 9 177, 5 177, 12 0.083 0.163 0.611 0.2142 1.09 0.789 1.5 -0.0543 0.452 0.904 0.04368 0.947 0.391 2.3 -0.274 0.527 0.602 0.2202 0.76 0.271 2.13 0.202 0.419 0.63 0.2006 1.22 0.539 2.78 PRS_PLINK_0.001 965 Poisoning by analgesics, antipyretics, and antirheumatics Both 976 15764 18 injuries & poisonings gray50 15764, 976 3941, 244 3941, 257 3941, 246 3941, 229 -0.0222 0.0333 0.505 0.2971 0.978 0.916 1.04 0.0551 0.0921 0.55 0.2599 1.06 0.882 1.27 0.0168 0.0933 0.857 0.06705 1.02 0.847 1.22 -0.0744 0.0951 0.434 0.3627 0.928 0.77 1.12 PRS_PLINK_0.001 965.1 Opiates and related narcotics causing adverse effects in therapeutic use Both 212 3010 18 injuries & poisonings gray50 3010, 212 753, 55 752, 60 752, 56 753, 41 -0.0965 0.0716 0.178 0.7496 0.908 0.789 1.04 0.107 0.191 0.576 0.2397 1.11 0.765 1.62 0.00884 0.195 0.964 0.016 1.01 0.688 1.48 -0.334 0.21 0.112 0.9493 0.716 0.474 1.08 PRS_PLINK_0.001 965.2 Antirheumatics causing adverse effects in therapeutic use Both 44 1293 18 injuries & poisonings gray50 1293, 44 324, 9 323, 17 323, 10 323, 8 -0.0784 0.144 0.587 0.2312 0.925 0.697 1.23 0.663 0.395 0.0927 1.033 1.94 0.896 4.21 0.111 0.43 0.796 0.09919 1.12 0.481 2.6 -0.0369 0.448 0.934 0.02948 0.964 0.401 2.32 PRS_PLINK_0.001 965.3 Salicylates causing adverse effects in therapeutic use Both 46 1023 18 injuries & poisonings gray50 1023, 46 256, 15 256, 16 255, 7 256, 8 -0.301 0.149 0.0435 1.362 0.74 0.552 0.991 0.0909 0.357 0.799 0.0974 1.1 0.544 2.2 -0.668 0.436 0.125 0.9015 0.513 0.218 1.2 -0.504 0.418 0.228 0.6423 0.604 0.266 1.37 PRS_PLINK_0.001 966 Poisoning by anticonvulsants and anti-Parkinsonism drugs Both 44 1315 18 injuries & poisonings gray50 1315, 44 329, 12 329, 11 328, 14 329, 7 -0.186 0.15 0.214 0.6689 0.831 0.62 1.11 -0.101 0.401 0.801 0.09661 0.904 0.412 1.98 0.0851 0.382 0.824 0.08426 1.09 0.515 2.3 -0.409 0.445 0.358 0.4457 0.665 0.278 1.59 PRS_PLINK_0.001 967 Adverse effects of sedatives or other central nervous system depressants and anesthetics Both 110 1491 18 injuries & poisonings gray50 1491, 110 373, 20 373, 32 372, 29 373, 29 0.153 0.0994 0.124 0.9059 1.17 0.959 1.42 0.49 0.288 0.0893 1.049 1.63 0.927 2.87 0.395 0.292 0.177 0.7528 1.48 0.837 2.63 0.361 0.294 0.22 0.6572 1.43 0.806 2.56 PRS_PLINK_0.001 969 Poisoning by psychotropic agents Both 169 5052 18 injuries & poisonings gray50 5052, 169 1263, 41 1263, 43 1263, 43 1263, 42 0.0101 0.0781 0.897 0.04706 1.01 0.867 1.18 0.0615 0.218 0.778 0.1091 1.06 0.694 1.63 0.0545 0.219 0.803 0.09524 1.06 0.688 1.62 0.0346 0.22 0.875 0.05809 1.04 0.673 1.59 PRS_PLINK_0.001 971 Poisoning by drugs primarily affecting the autonomic nervous system Both 20 485 18 injuries & poisonings gray50 485, 20 122, 1 121, 6 121, 7 121, 6 0.563 0.223 0.0114 1.943 1.76 1.14 2.72 1.54 0.807 0.0565 1.248 4.66 0.958 22.7 1.51 0.782 0.0531 1.275 4.53 0.98 21 1.45 0.779 0.0632 1.199 4.25 0.924 19.6 PRS_PLINK_0.001 972 Poisoning by agents primarily affecting the cardiovascular system Both 21 733 18 injuries & poisonings gray50 733, 21 184, 5 183, 2 183, 4 183, 10 0.163 0.202 0.419 0.3773 1.18 0.792 1.75 -0.736 0.655 0.261 0.5831 0.479 0.133 1.73 -0.19 0.569 0.738 0.1318 0.827 0.271 2.52 0.553 0.504 0.273 0.5645 1.74 0.647 4.67 PRS_PLINK_0.001 972.6 Antihypertensive agents causing adverse effects Both 3 227 18 injuries & poisonings gray50 227, 3 57, 0 57, 1 56, 0 57, 2 0.443 0.379 0.242 0.6154 1.56 0.741 3.27 0.892 1.07 0.403 0.3943 2.44 0.301 19.8 -0.156 1.05 0.882 0.05473 0.856 0.11 6.65 1.28 1.09 0.24 0.619 3.6 0.424 30.5 PRS_PLINK_0.001 973 Poisoning by agents primarily affecting the gastrointestinal system Both 10 298 18 injuries & poisonings gray50 298, 10 75, 4 74, 2 74, 2 75, 2 -0.378 0.273 0.167 0.7775 0.686 0.401 1.17 -0.576 0.721 0.424 0.3721 0.562 0.137 2.31 -0.138 0.751 0.855 0.06822 0.872 0.2 3.79 -0.512 0.72 0.477 0.3211 0.599 0.146 2.46 PRS_PLINK_0.001 974 Poisoning by water, mineral, and uric acid metabolism drugs Both 5 245 18 injuries & poisonings gray50 245, 5 62, 2 61, 1 61, 0 61, 2 -0.114 0.336 0.733 0.1347 0.892 0.462 1.72 -0.401 0.938 0.669 0.1746 0.67 0.107 4.21 -1.8 1.29 0.162 0.7902 0.165 0.0131 2.07 -0.173 0.878 0.844 0.07369 0.841 0.151 4.7 PRS_PLINK_0.001 975 Poisoning by agents primarily acting on the smooth and skeletal muscles and respiratory system Both 9 149 18 injuries & poisonings gray50 149, 9 38, 2 37, 5 37, 1 37, 1 -0.667 0.382 0.081 1.091 0.513 0.243 1.09 0.355 0.811 0.661 0.1796 1.43 0.291 6.98 -0.95 1.04 0.362 0.4418 0.387 0.0503 2.98 -1.32 1.2 0.27 0.5689 0.266 0.0254 2.79 PRS_PLINK_0.001 976 Poisoning by agents primarily affecting skin & mucous membrane, ophthalmological, otorhinolaryngological, & dental drugs Both 4 142 18 injuries & poisonings gray50 142, 4 36, 2 35, 0 35, 0 36, 2 -0.197 0.368 0.592 0.2277 0.821 0.399 1.69 -0.992 1.08 0.359 0.4455 0.371 0.0446 3.08 -0.588 1.08 0.585 0.233 0.556 0.0674 4.58 0.0456 0.828 0.956 0.01949 1.05 0.206 5.31 PRS_PLINK_0.001 977 Personal history of allergy to medicinal agents Both 41 635 18 injuries & poisonings gray50 635, 41 159, 8 159, 11 158, 10 159, 12 0.0648 0.161 0.688 0.1627 1.07 0.778 1.46 0.263 0.446 0.555 0.2559 1.3 0.543 3.12 0.14 0.458 0.759 0.1195 1.15 0.469 2.82 0.352 0.458 0.443 0.3538 1.42 0.579 3.49 PRS_PLINK_0.001 979 Adverse drug events and drug allergies Both 96 1841 18 injuries & poisonings gray50 1841, 96 461, 27 460, 16 460, 32 460, 21 0.0738 0.104 0.479 0.3193 1.08 0.877 1.32 -0.503 0.31 0.104 0.9816 0.604 0.329 1.11 0.213 0.264 0.421 0.3762 1.24 0.737 2.07 -0.187 0.292 0.522 0.2825 0.829 0.468 1.47 PRS_PLINK_0.001 981 Toxic effect of (non-ethyl) alcohol and petroleum and other solvents Both 19 515 18 injuries & poisonings gray50 515, 19 129, 8 129, 6 128, 3 129, 2 -0.561 0.222 0.0114 1.944 0.571 0.37 0.881 -0.306 0.521 0.557 0.2543 0.736 0.265 2.04 -0.946 0.605 0.118 0.9274 0.388 0.119 1.27 -1.22 0.666 0.0677 1.169 0.296 0.0803 1.09 PRS_PLINK_0.001 986 Toxic effect of carbon monoxide Both 9 147 18 injuries & poisonings gray50 147, 9 37, 1 37, 6 36, 2 37, 0 -0.285 0.368 0.438 0.3581 0.752 0.366 1.55 1.51 0.897 0.093 1.031 4.51 0.778 26.2 0.488 0.977 0.617 0.2095 1.63 0.24 11.1 -1.65 1.28 0.199 0.7004 0.193 0.0156 2.38 PRS_PLINK_0.001 987 Toxic effect of other gases, fumes, or vapors Both 9 258 18 injuries & poisonings gray50 258, 9 65, 2 64, 3 64, 0 65, 4 0.202 0.303 0.504 0.2974 1.22 0.676 2.22 0.439 0.813 0.59 0.2295 1.55 0.315 7.63 -1.71 1.17 0.144 0.8419 0.181 0.0183 1.79 0.705 0.744 0.344 0.4639 2.02 0.471 8.7 PRS_PLINK_0.001 988 Toxic effect of noxious substances eaten as food Both 24 282 18 injuries & poisonings gray50 282, 24 71, 8 70, 6 70, 2 71, 8 0.126 0.212 0.552 0.2578 1.13 0.749 1.72 -0.0917 0.566 0.871 0.0599 0.912 0.301 2.76 -0.98 0.707 0.166 0.7811 0.375 0.0939 1.5 0.304 0.543 0.576 0.2399 1.36 0.467 3.93 PRS_PLINK_0.001 989 Toxic effect of other substances, chiefly nonmedicinal as to source Both 10 229 18 injuries & poisonings gray50 229, 10 58, 1 57, 5 57, 3 57, 1 0.175 0.287 0.54 0.2673 1.19 0.68 2.09 2.04 0.913 0.0255 1.594 7.68 1.28 45.9 0.761 0.933 0.415 0.3824 2.14 0.344 13.3 0.011 0.993 0.991 0.00385 1.01 0.144 7.09 PRS_PLINK_0.001 990 Effects radiation NOS Both 469 7684 18 injuries & poisonings gray50 7684, 469 1921, 104 1921, 125 1921, 120 1921, 120 0.0667 0.0483 0.167 0.776 1.07 0.972 1.18 0.176 0.136 0.195 0.7094 1.19 0.914 1.56 0.138 0.137 0.314 0.5033 1.15 0.877 1.5 0.137 0.138 0.321 0.4936 1.15 0.875 1.5 PRS_PLINK_0.001 994 Sepsis and SIRS Both 284 7570 18 injuries & poisonings gray50 7570, 284 1893, 75 1892, 83 1892, 56 1893, 70 -0.0186 0.0603 0.758 0.1201 0.982 0.872 1.1 0.113 0.161 0.484 0.3149 1.12 0.816 1.54 -0.27 0.178 0.128 0.8915 0.763 0.539 1.08 -0.073 0.168 0.664 0.1781 0.93 0.669 1.29 PRS_PLINK_0.001 994.2 Sepsis Both 284 7570 18 injuries & poisonings gray50 7570, 284 1893, 75 1892, 83 1892, 56 1893, 70 -0.0186 0.0603 0.758 0.1201 0.982 0.872 1.1 0.113 0.161 0.484 0.3149 1.12 0.816 1.54 -0.27 0.178 0.128 0.8915 0.763 0.539 1.08 -0.073 0.168 0.664 0.1781 0.93 0.669 1.29 PRS_PLINK_0.001 1000 Burns Both 91 1490 18 injuries & poisonings gray50 1490, 91 373, 24 372, 15 372, 26 373, 26 -0.0305 0.11 0.781 0.1073 0.97 0.783 1.2 -0.451 0.324 0.164 0.7856 0.637 0.338 1.2 0.0984 0.284 0.729 0.1371 1.1 0.632 1.93 0.108 0.287 0.707 0.1503 1.11 0.635 1.95 PRS_PLINK_0.001 1001 Foreign body injury Both 227 2980 18 injuries & poisonings gray50 2980, 227 745, 61 745, 59 745, 62 745, 45 -0.0497 0.0687 0.469 0.3284 0.952 0.832 1.09 -0.0337 0.187 0.857 0.06677 0.967 0.67 1.4 0.00623 0.186 0.973 0.01176 1.01 0.699 1.45 -0.318 0.202 0.115 0.9409 0.727 0.49 1.08 PRS_PLINK_0.001 1002 Symptoms concerning nutrition, metabolism, and development Both 851 13887 18 injuries & poisonings gray50 13887, 851 3472, 243 3472, 201 3471, 195 3472, 212 -0.0466 0.0353 0.187 0.7281 0.954 0.891 1.02 -0.184 0.0981 0.0608 1.216 0.832 0.686 1.01 -0.22 0.0989 0.0265 1.577 0.803 0.661 0.975 -0.132 0.0971 0.173 0.7611 0.876 0.724 1.06 PRS_PLINK_0.001 1004 Other signs and symptoms involving emotional state Both 23 776 18 injuries & poisonings gray50 776, 23 194, 4 194, 10 194, 3 194, 6 -0.0356 0.199 0.858 0.06642 0.965 0.653 1.43 0.844 0.54 0.118 0.9275 2.33 0.807 6.7 -0.37 0.624 0.554 0.2568 0.691 0.203 2.35 0.561 0.581 0.334 0.4756 1.75 0.561 5.47 PRS_PLINK_0.001 1005 Other symptoms Both 159 3647 18 injuries & poisonings gray50 3647, 159 912, 42 912, 42 911, 37 912, 38 -0.0134 0.0802 0.868 0.06157 0.987 0.843 1.15 0.0081 0.219 0.97 0.01301 1.01 0.656 1.55 -0.12 0.226 0.594 0.226 0.887 0.569 1.38 -0.0802 0.226 0.722 0.1414 0.923 0.593 1.44 PRS_PLINK_0.001 1006 Crushing injury Both 36 639 18 injuries & poisonings gray50 639, 36 160, 4 160, 11 159, 7 160, 14 0.437 0.174 0.0118 1.927 1.55 1.1 2.18 0.872 0.53 0.0996 1.002 2.39 0.847 6.75 0.489 0.556 0.38 0.4208 1.63 0.548 4.85 1.17 0.519 0.0238 1.623 3.23 1.17 8.93 PRS_PLINK_0.001 1007 Injury to blood vessels Both 53 661 18 injuries & poisonings gray50 661, 53 166, 7 165, 12 165, 9 165, 25 0.398 0.139 0.00428 2.369 1.49 1.13 1.95 0.519 0.453 0.252 0.5991 1.68 0.692 4.08 0.0791 0.478 0.869 0.06121 1.08 0.424 2.76 1.29 0.424 0.00232 2.635 3.64 1.59 8.36 PRS_PLINK_0.001 1008 Crushing or internal injury to organs Both 192 2561 18 injuries & poisonings gray50 2561, 192 641, 53 640, 49 640, 35 640, 55 -0.00557 0.073 0.939 0.02729 0.994 0.862 1.15 -0.0474 0.204 0.816 0.08828 0.954 0.639 1.42 -0.372 0.221 0.0926 1.033 0.689 0.446 1.06 0.091 0.2 0.649 0.188 1.1 0.74 1.62 PRS_PLINK_0.001 1009 Injury, NOS Both 1559 21328 18 injuries & poisonings gray50 21328, 1559 5332, 394 5332, 413 5332, 363 5332, 389 -0.00661 0.0262 0.801 0.09637 0.993 0.944 1.05 0.0479 0.073 0.512 0.2905 1.05 0.909 1.21 -0.0712 0.0754 0.345 0.4618 0.931 0.803 1.08 -0.00157 0.0744 0.983 0.00738 0.998 0.863 1.16 PRS_PLINK_0.001 1010 Other tests Both 1120 15051 18 injuries & poisonings gray50 15051, 1120 3763, 265 3763, 291 3762, 289 3763, 275 0.0129 0.0311 0.68 0.1677 1.01 0.953 1.08 0.102 0.0878 0.247 0.6081 1.11 0.932 1.32 0.0986 0.0882 0.263 0.5796 1.1 0.929 1.31 0.0385 0.0893 0.666 0.1765 1.04 0.872 1.24 PRS_PLINK_0.001 1011 Complications of surgical and medical procedures Both 1581 22966 18 injuries & poisonings gray50 22966, 1581 5742, 391 5741, 432 5741, 374 5742, 384 -0.0238 0.0261 0.363 0.4397 0.977 0.928 1.03 0.109 0.0723 0.131 0.8824 1.12 0.968 1.28 -0.0389 0.0749 0.603 0.2196 0.962 0.831 1.11 -0.014 0.0746 0.851 0.07008 0.986 0.852 1.14 PRS_PLINK_0.001 1012 Late effect Both 18 271 18 injuries & poisonings gray50 271, 18 68, 4 68, 5 67, 4 68, 5 0.0584 0.236 0.805 0.0943 1.06 0.667 1.68 0.214 0.651 0.743 0.1293 1.24 0.346 4.44 0.0187 0.682 0.978 0.009631 1.02 0.268 3.87 0.0458 0.668 0.945 0.02443 1.05 0.283 3.88 PRS_PLINK_0.001 1013 Asphyxia and hypoxemia Both 27 779 18 injuries & poisonings gray50 779, 27 195, 3 195, 5 194, 12 195, 7 0.205 0.192 0.285 0.5449 1.23 0.843 1.79 0.258 0.637 0.685 0.1642 1.29 0.371 4.51 1.27 0.579 0.0286 1.543 3.55 1.14 11.1 0.463 0.608 0.446 0.3506 1.59 0.483 5.23 PRS_PLINK_0.001 1014 Effects of heat, cold and air pressure Both 14 148 18 injuries & poisonings gray50 148, 14 37, 2 37, 3 37, 5 37, 4 0.237 0.267 0.376 0.4251 1.27 0.75 2.14 0.297 0.87 0.733 0.1347 1.35 0.244 7.41 0.763 0.783 0.33 0.4821 2.15 0.462 9.95 0.769 0.861 0.372 0.4293 2.16 0.399 11.7 PRS_PLINK_0.001 1015 Effects of other external causes Both 611 10796 18 injuries & poisonings gray50 10796, 611 2699, 140 2699, 170 2699, 148 2699, 153 0.00647 0.0418 0.877 0.05705 1.01 0.927 1.09 0.189 0.117 0.107 0.9708 1.21 0.96 1.52 0.0428 0.121 0.723 0.141 1.04 0.824 1.32 0.0682 0.12 0.571 0.2437 1.07 0.846 1.36 PRS_PLINK_0.001 1019 Other ill-defined and unknown causes of morbidity and mortality Both 3269 41342 18 injuries & poisonings gray50 41342, 3269 10335, 784 10335, 839 10335, 800 10336, 846 0.0221 0.0183 0.226 0.6453 1.02 0.986 1.06 0.0702 0.0516 0.174 0.7601 1.07 0.97 1.19 0.0155 0.0522 0.767 0.1152 1.02 0.917 1.13 0.0799 0.0517 0.122 0.9122 1.08 0.979 1.2 PRS_PLINK_0.001