phewas_code phewas_string sex MatchedCases MatchedControls groupnum group color N N_Q1 N_Q2 N_Q3 N_Q4 PRS_BETA PRS_SEBETA PRS_P PRS_LOG10P PRS_OR PRS_CI1 PRS_CI2 Q1Q2_BETA Q1Q2_SEBETA Q1Q2_P Q1Q2_LOG10P Q1Q2_OR Q1Q2_CI1 Q1Q2_CI2 Q1Q3_BETA Q1Q3_SEBETA Q1Q3_P Q1Q3_LOG10P Q1Q3_OR Q1Q3_CI1 Q1Q3_CI2 Q1Q4_BETA Q1Q4_SEBETA Q1Q4_P Q1Q4_LOG10P Q1Q4_OR Q1Q4_CI1 Q1Q4_CI2 predictor exclude 008 Intestinal infection Both 55 284 1 infectious diseases blue 284, 55 70, 19 71, 12 71, 12 71, 12 -0.122 0.149 0.414 0.383 0.885 0.66 1.19 -0.456 0.424 0.282 0.549 0.634 0.269 1.44 -0.453 0.426 0.288 0.541 0.636 0.271 1.45 -0.498 0.42 0.236 0.628 0.608 0.262 1.37 PRS_PLINK_0.000199526231496888 FALSE 008.5 Bacterial enteritis Both 13 113 1 infectious diseases blue 113, 13 29, 4 28, 2 28, 2 28, 5 0.252 0.276 0.36 0.443 1.29 0.749 2.25 -0.241 0.912 0.792 0.101 0.786 0.0944 5.88 0.558 0.997 0.576 0.24 1.75 0.213 20.8 0.304 0.76 0.689 0.162 1.35 0.301 6.63 PRS_PLINK_0.000199526231496888 TRUE 008.52 Intestinal infection due to C. difficile Both 7 89 1 infectious diseases blue 89, 7 23, 1 22, 2 22, 1 22, 3 0.169 0.34 0.619 0.208 1.18 0.588 2.36 0.551 1.13 0.626 0.203 1.74 0.00602 37.8 0.0312 1.07 0.977 0.01 1.03 0.0954 16.1 1.2 1.1 0.277 0.558 3.31 0.376 26000 PRS_PLINK_0.000199526231496888 TRUE 008.6 Viral Enteritis Both 16 72 1 infectious diseases blue 72, 16 18, 5 18, 6 18, 3 18, 2 -0.151 0.313 0.63 0.201 0.86 0.457 1.58 -0.0321 0.726 0.965 0.016 0.968 0.245 3.73 -0.101 0.839 0.904 0.044 0.904 0.173 4.53 -0.963 1 0.337 0.472 0.382 0.039 2.36 PRS_PLINK_0.000199526231496888 TRUE 010 Tuberculosis Both 3 19 1 infectious diseases blue 19, 3 5, 2 5, 0 4, 1 5, 0 0.00941 0.815 0.991 0.004 1.01 0.00939 9.5 -0.498 2.04 0.807 0.093 0.608 0.524 18.9 -2.82 4.69 0.547 0.262 0.0594 0.0476 44.9 -0.73 2.13 0.732 0.136 0.482 0.0012 27.7 PRS_PLINK_0.000199526231496888 TRUE 031 Diseases due to other mycobacteria Both 1 7 1 infectious diseases blue 7, 1 2, 1 2, 0 1, 0 2, 0 -0.496 2.89 0.864 0.064 0.609 0.0482 6.35 -0.102 402 1 0 0.903 0.394 1.32 0.0982 3190 1 0 1.1 0.181 2.67 0.974 22900000 1 0 2.65 0.000281 9940 PRS_PLINK_0.000199526231496888 TRUE 038 Septicemia Both 31 151 1 infectious diseases blue 151, 31 38, 8 38, 10 37, 8 38, 5 -0.117 0.197 0.55 0.26 0.889 0.603 1.31 0.226 0.537 0.673 0.172 1.25 0.448 3.64 -0.193 0.592 0.745 0.128 0.825 0.254 2.6 -0.264 0.625 0.672 0.173 0.768 0.214 2.58 PRS_PLINK_0.000199526231496888 TRUE 038.1 Gram negative septicemia Both 8 29 1 infectious diseases blue 29, 8 8, 2 7, 4 7, 0 7, 2 0.00936 0.47 0.984 0.007 1.01 0.396 4.21 1.99 1.53 0.193 0.714 7.34 0.69 1410 -0.113 1.87 0.952 0.021 0.893 0.00251 87.7 -0.156 1.28 0.903 0.044 0.855 0.0291 10.2 PRS_PLINK_0.000199526231496888 TRUE 038.2 Gram positive septicemia Both 2 15 1 infectious diseases blue 15, 2 4, 1 4, 0 3, 1 4, 0 -0.309 0.764 0.686 0.164 0.734 0.024 5.25 0.744 45.1 0.987 0.006 2.1 2.31 4.45 1.61 4960000 1 0 4.99 0.0501 345 -1.79 90.5 0.984 0.007 0.168 0.0026 2.76 PRS_PLINK_0.000199526231496888 TRUE 038.3 Bacteremia Both 13 72 1 infectious diseases blue 72, 13 18, 2 18, 5 18, 4 18, 2 -0.0192 0.304 0.95 0.022 0.981 0.541 1.76 0.933 1.01 0.356 0.448 2.54 0.419 30.8 0.41 1.05 0.695 0.158 1.51 0.13 18.4 -0.118 0.945 0.901 0.045 0.889 0.139 6.77 PRS_PLINK_0.000199526231496888 TRUE 041 Bacterial infection NOS Both 107 332 1 infectious diseases blue 332, 107 82, 25 83, 27 83, 34 83, 21 -0.000974 0.116 0.993 0.003 0.999 0.797 1.25 0.0295 0.33 0.929 0.032 1.03 0.543 1.95 0.273 0.315 0.387 0.412 1.31 0.716 2.43 -0.159 0.351 0.651 0.187 0.853 0.429 1.68 PRS_PLINK_0.000199526231496888 FALSE 041.1 Staphylococcus infections Both 19 114 1 infectious diseases blue 114, 19 29, 3 28, 2 28, 8 29, 6 0.312 0.256 0.223 0.651 1.37 0.829 2.35 -0.141 0.921 0.878 0.057 0.868 0.1 6.89 0.852 0.735 0.246 0.609 2.34 0.569 11.7 0.532 0.719 0.459 0.338 1.7 0.429 7.75 PRS_PLINK_0.000199526231496888 TRUE 041.11 Methicillin sensitive Staphylococcus aureus Both 9 63 1 infectious diseases blue 63, 9 16, 2 16, 2 15, 3 16, 2 0.0916 0.325 0.778 0.109 1.1 0.563 2.18 0.025 1.07 0.981 0.008 1.03 0.0836 10.6 1.14 1.13 0.311 0.507 3.13 0.361 46.4 -0.111 0.971 0.909 0.042 0.895 0.125 9.79 PRS_PLINK_0.000199526231496888 TRUE 041.12 Methicillin resistant Staphylococcus aureus Both 9 65 1 infectious diseases blue 65, 9 17, 1 16, 0 16, 6 16, 2 0.303 0.337 0.369 0.433 1.35 0.692 2.83 -0.313 1.17 0.789 0.103 0.731 0.00998 27 2.02 1.32 0.127 0.896 7.51 0.666 225 0.557 1.17 0.633 0.199 1.74 0.16 37.4 PRS_PLINK_0.000199526231496888 TRUE 041.2 Streptococcus infection Both 32 118 1 infectious diseases blue 118, 32 30, 7 29, 11 29, 6 30, 8 0.000962 0.219 0.996 0.002 1 0.65 1.53 0.206 0.619 0.739 0.132 1.23 0.372 4.02 0.209 0.649 0.747 0.126 1.23 0.352 4.45 0.328 0.667 0.622 0.206 1.39 0.383 5.14 PRS_PLINK_0.000199526231496888 TRUE 041.21 Rheumatic fever / chorea Both 2 12 1 infectious diseases blue 12, 2 3, 1 3, 1 3, 0 3, 0 -0.386 1.59 0.808 0.093 0.68 0.000184 10.5 0.061 28.8 0.998 0.001 1.06 0.774 6.36e+08 0.0249 939000 1 0 1.03 0.677 1.47 0.0468 99.7 1 0 1.05 0.59 1.98 PRS_PLINK_0.000199526231496888 TRUE 041.4 E. coli Both 17 105 1 infectious diseases blue 105, 17 26, 5 26, 2 26, 6 26, 4 -0.184 0.243 0.449 0.348 0.832 0.514 1.34 -1.06 0.996 0.288 0.541 0.347 0.0311 2.33 -0.248 0.73 0.734 0.134 0.78 0.177 3.22 -0.447 0.787 0.57 0.244 0.64 0.128 2.88 PRS_PLINK_0.000199526231496888 TRUE 041.8 H. pylori Both 3 24 1 infectious diseases blue 24, 3 5, 0 6, 1 6, 1 6, 1 0.205 0.592 0.73 0.137 1.23 0.439 6.99 0.304 7.28 0.967 0.015 1.35 1.31 1.4 1.27 2.25 0.573 0.242 3.57 0.0869 453 -1.19 11.5 0.918 0.037 0.304 2.25e-08 19400000 PRS_PLINK_0.000199526231496888 TRUE 041.9 Infection with drug-resistant microorganisms Both 4 37 1 infectious diseases blue 37, 4 10, 0 9, 2 9, 0 9, 2 0.23 0.534 0.666 0.176 1.26 0.45 5.86 -0.341 2.86 0.905 0.043 0.711 2.41e-06 422 1.4 1.89 0.461 0.336 4.04 0.107 1960 PRS_PLINK_0.000199526231496888 TRUE 053 Herpes zoster Both 28 77 1 infectious diseases blue 77, 28 20, 10 19, 5 19, 6 19, 7 -0.255 0.24 0.286 0.543 0.775 0.489 1.21 -0.555 0.684 0.418 0.379 0.574 0.143 2.03 -0.164 0.65 0.801 0.096 0.849 0.25 2.83 -0.168 0.65 0.796 0.099 0.846 0.248 2.75 PRS_PLINK_0.000199526231496888 TRUE 053.1 Herpes zoster with nervous system complications Both 4 8 1 infectious diseases blue 8, 4 2, 2 2, 0 2, 0 2, 2 -0.314 1 0.754 0.122 0.731 0.708 0.762 -0.171 413 1 0 0.843 0.522 0.925 -0.142 438 1 0 0.867 0.362 0.648 -0.233 2360 1 0 0.792 0.263 1.16 PRS_PLINK_0.000199526231496888 TRUE 054 Herpes simplex Both 35 136 1 infectious diseases blue 136, 35 34, 9 34, 9 34, 11 34, 6 -0.178 0.192 0.354 0.451 0.837 0.572 1.21 -0.0211 0.558 0.97 0.013 0.979 0.334 2.88 0.17 0.531 0.749 0.125 1.18 0.427 3.4 -0.68 0.619 0.272 0.565 0.507 0.145 1.64 PRS_PLINK_0.000199526231496888 TRUE 070 Viral hepatitis Both 7 41 1 infectious diseases blue 41, 7 11, 3 10, 1 10, 2 10, 1 -0.0965 0.408 0.813 0.09 0.908 0.41 1.98 -0.309 1.69 0.855 0.068 0.734 0.0106 19 -0.389 1.14 0.732 0.136 0.678 0.0584 5.14 -0.0215 1.36 0.987 0.005 0.979 0.0395 16.5 PRS_PLINK_0.000199526231496888 TRUE 070.1 Viral hepatitis A Both 1 3 1 infectious diseases blue 3, 1 1, 0 1, 0 0, 1 1, 0 0.0219 4860 1 0 1.02 0.704 1.52 -0.0024 10.8 1 0 0.998 0.918 1.07 PRS_PLINK_0.000199526231496888 TRUE 070.2 Viral hepatitis B Both 0 9 1 infectious diseases blue 9, 0 3 2 2 2 PRS_PLINK_0.000199526231496888 TRUE 070.3 Viral hepatitis C Both 4 25 1 infectious diseases blue 25, 4 7, 2 6, 0 6, 2 6, 0 -0.604 0.612 0.323 0.49 0.546 0.144 1.51 -0.5 1.84 0.785 0.105 0.607 0.00359 24.3 1.26 2.02 0.533 0.273 3.53 0.0974 13300 -0.982 1.81 0.587 0.231 0.374 0.00246 13.4 PRS_PLINK_0.000199526231496888 TRUE 070.4 Chronic hepatitis Both 2 9 1 infectious diseases blue 9, 2 3, 2 2, 0 2, 0 2, 0 0.0699 3.4 0.984 0.007 1.07 0.000373 195 0.0428 663 1 0 1.04 0.673 1.71 -0.853 16900000 1 0 0.426 0.019 17.4 -0.0529 1860 1 0 0.948 0.339 2.56 PRS_PLINK_0.000199526231496888 TRUE 070.9 Hepatitis NOS Both 12 39 1 infectious diseases blue 39, 12 10, 4 10, 2 9, 4 10, 2 0.151 0.406 0.709 0.149 1.16 0.542 2.55 -0.343 1.15 0.766 0.116 0.709 0.0668 7.85 -1.29 1.31 0.325 0.489 0.274 0.0078 2.59 -0.623 1.24 0.617 0.21 0.537 0.0473 5.04 PRS_PLINK_0.000199526231496888 TRUE 071 Human immunodeficiency virus [HIV] disease Both 1 8 1 infectious diseases blue 8, 1 2, 0 2, 1 2, 0 2, 0 -0.274 21.7 0.99 0.004 0.76 0.000127 4380 0.121 586 1 0 1.13 0.673 3.22 PRS_PLINK_0.000199526231496888 TRUE 071.1 HIV infection, symptomatic Both 0 5 1 infectious diseases blue 5, 0 2 1 1 1 PRS_PLINK_0.000199526231496888 TRUE 078 Viral warts & HPV Both 85 203 1 infectious diseases blue 203, 85 50, 19 51, 21 50, 23 51, 22 -0.036 0.136 0.791 0.102 0.965 0.743 1.25 -0.0411 0.414 0.921 0.036 0.96 0.431 2.12 0.0234 0.403 0.954 0.021 1.02 0.471 2.22 0.232 0.4 0.562 0.25 1.26 0.589 2.73 PRS_PLINK_0.000199526231496888 FALSE 079 Viral infection Both 157 214 1 infectious diseases blue 214, 157 53, 40 53, 32 53, 39 54, 46 0.066 0.11 0.549 0.26 1.07 0.864 1.32 -0.115 0.323 0.721 0.142 0.891 0.478 1.66 -0.016 0.311 0.959 0.018 0.984 0.542 1.79 0.0983 0.316 0.756 0.122 1.1 0.601 2.02 PRS_PLINK_0.000199526231496888 FALSE 079.1 Varicella infection Both 92 205 1 infectious diseases blue 205, 92 51, 23 51, 19 51, 23 51, 27 0.0615 0.13 0.636 0.197 1.06 0.828 1.37 -0.041 0.394 0.917 0.038 0.96 0.448 2.06 0.0148 0.376 0.969 0.014 1.01 0.493 2.09 0.146 0.376 0.698 0.156 1.16 0.564 2.38 PRS_PLINK_0.000199526231496888 FALSE 079.2 Infectious mononucleosis Both 8 14 1 infectious diseases blue 14, 8 4, 2 3, 3 3, 1 4, 2 0.0323 0.647 0.96 0.018 1.03 0.254 4.08 -0.589 1.98 0.766 0.116 0.555 0.456 205 4.91 7.42 0.508 0.294 136 0.00891 186 1.29 2.82 0.648 0.188 3.63 0.0142 351000 PRS_PLINK_0.000199526231496888 TRUE 079.9 Viremia, NOS Both 31 60 1 infectious diseases blue 60, 31 15, 8 15, 8 15, 8 15, 7 0.0975 0.253 0.7 0.155 1.1 0.681 1.81 0.379 0.826 0.646 0.19 1.46 0.316 7.29 0.652 0.819 0.426 0.371 1.92 0.416 9.88 0.2 0.799 0.802 0.096 1.22 0.272 5.58 PRS_PLINK_0.000199526231496888 TRUE 080 Postoperative infection Both 32 253 1 infectious diseases blue 253, 32 63, 10 63, 6 63, 10 63, 6 -0.0775 0.18 0.667 0.176 0.925 0.648 1.32 -0.593 0.539 0.271 0.567 0.553 0.178 1.58 0.0608 0.489 0.901 0.045 1.06 0.402 2.82 -0.412 0.565 0.466 0.332 0.662 0.205 1.99 PRS_PLINK_0.000199526231496888 TRUE 081 Infection/inflammation of internal prosthetic device; implant; and graft Both 18 117 1 infectious diseases blue 117, 18 30, 4 29, 10 29, 3 29, 1 -0.39 0.277 0.159 0.798 0.677 0.385 1.15 0.899 0.662 0.174 0.759 2.46 0.732 9.94 -0.401 0.949 0.673 0.172 0.67 0.078 4.99 -2.37 1.28 0.063 1.201 0.0934 0.00268 0.882 PRS_PLINK_0.000199526231496888 TRUE 090 Sexually transmitted infections (not HIV or hepatitis) Both 34 146 1 infectious diseases blue 146, 34 36, 10 36, 8 36, 8 37, 8 -0.0634 0.189 0.737 0.133 0.939 0.651 1.35 -0.0737 0.586 0.9 0.046 0.929 0.294 2.85 0.0294 0.549 0.957 0.019 1.03 0.355 2.98 -0.253 0.654 0.699 0.156 0.776 0.21 2.71 PRS_PLINK_0.000199526231496888 TRUE 110 Dermatophytosis / Dermatomycosis Both 52 218 1 infectious diseases blue 218, 52 55, 13 54, 12 54, 15 55, 12 -0.0167 0.165 0.919 0.037 0.983 0.714 1.36 -0.146 0.482 0.762 0.118 0.864 0.329 2.23 0.154 0.44 0.727 0.139 1.17 0.497 2.76 -0.0549 0.461 0.905 0.043 0.947 0.383 2.32 PRS_PLINK_0.000199526231496888 FALSE 110.1 Dermatophytosis Both 47 185 1 infectious diseases blue 185, 47 47, 14 46, 8 46, 15 46, 10 -0.00927 0.173 0.957 0.019 0.991 0.708 1.39 -0.482 0.561 0.39 0.409 0.617 0.196 1.83 0.114 0.453 0.801 0.096 1.12 0.467 2.71 -0.201 0.484 0.678 0.169 0.818 0.314 2.07 PRS_PLINK_0.000199526231496888 TRUE 110.11 Dermatophytosis of nail Both 27 95 1 infectious diseases blue 95, 27 24, 7 24, 9 23, 4 24, 7 0.0483 0.243 0.842 0.075 1.05 0.657 1.69 0.351 0.775 0.651 0.186 1.42 0.323 7.02 -0.755 0.802 0.347 0.46 0.47 0.0845 2.2 0.181 0.667 0.786 0.104 1.2 0.338 4.44 PRS_PLINK_0.000199526231496888 TRUE 110.12 Althete's foot Both 12 50 1 infectious diseases blue 50, 12 13, 1 12, 3 12, 3 13, 5 0.347 0.369 0.347 0.46 1.41 0.709 3.08 0.628 1.03 0.54 0.267 1.87 0.274 16.5 0.276 1.24 0.824 0.084 1.32 0.0802 26.5 2.13 1.34 0.114 0.943 8.38 0.884 331 PRS_PLINK_0.000199526231496888 TRUE 110.13 Dermatophytosis of the body Both 12 50 1 infectious diseases blue 50, 12 13, 4 12, 1 12, 7 13, 0 -0.212 0.324 0.512 0.291 0.809 0.431 1.47 -0.612 1.03 0.552 0.258 0.542 0.0326 3.75 1.68 1.12 0.133 0.877 5.39 0.751 92.7 -1.72 1.42 0.224 0.649 0.179 0.00222 1.82 PRS_PLINK_0.000199526231496888 TRUE 110.2 Dermatomycoses Both 10 42 1 infectious diseases blue 42, 10 11, 1 10, 4 10, 3 11, 2 0.131 0.42 0.754 0.122 1.14 0.529 2.65 0.906 1.17 0.441 0.356 2.47 0.323 27.7 1.01 1.6 0.529 0.277 2.75 0.184 151 0.849 1.35 0.528 0.277 2.34 0.213 223 PRS_PLINK_0.000199526231496888 TRUE 112 Candidiasis Both 98 285 1 infectious diseases blue 285, 98 72, 16 71, 29 71, 27 71, 25 0.0339 0.127 0.79 0.102 1.03 0.809 1.33 0.469 0.376 0.213 0.672 1.6 0.776 3.36 0.463 0.38 0.223 0.651 1.59 0.763 3.38 0.42 0.383 0.273 0.564 1.52 0.727 3.23 PRS_PLINK_0.000199526231496888 FALSE 112.3 Candidiasis of skin and nails Both 15 63 1 infectious diseases blue 63, 15 16, 2 16, 5 15, 2 16, 6 0.61 0.369 0.098 1.009 1.84 0.931 3.9 0.434 0.905 0.632 0.199 1.54 0.285 11.6 0.83 1.14 0.465 0.332 2.29 0.275 30 1.05 0.949 0.269 0.57 2.85 0.502 22.5 PRS_PLINK_0.000199526231496888 TRUE 117 Mycoses Both 6 46 1 infectious diseases blue 46, 6 12, 2 11, 1 11, 1 12, 2 0.115 0.339 0.735 0.134 1.12 0.568 2.23 -0.463 1.3 0.721 0.142 0.629 0.00127 22.7 -0.786 1.28 0.541 0.267 0.456 0.0194 4.73 0.468 1.17 0.69 0.161 1.6 0.16 51.1 PRS_PLINK_0.000199526231496888 TRUE 117.1 Histoplasmosis Both 1 6 1 infectious diseases blue 6, 1 2, 1 1, 0 1, 0 2, 0 -0.0561 985 1 0 0.945 0.765 0.997 0.148 7880 1 0 1.16 0.425 9.32 0.00684 113 1 0 1.01 0.92 1.04 0.211 4560 1 0 1.24 0.523 1.53 PRS_PLINK_0.000199526231496888 TRUE 117.4 Aspergillosis Both 2 17 1 infectious diseases blue 17, 2 5, 0 4, 0 4, 1 4, 1 0.547 0.757 0.47 0.328 1.73 0.349 40.6 0.575 2.3 0.803 0.095 1.78 0.0518 195 -0.337 6.27 0.957 0.019 0.714 0.669 0.772 PRS_PLINK_0.000199526231496888 TRUE 130 Spirochetal infection Both 2 12 1 infectious diseases blue 12, 2 3, 1 3, 0 3, 0 3, 1 0.865 1.75 0.62 0.207 2.38 0.00898 771 -2.28 17.9 0.899 0.046 0.102 0.00157 6.1 0.418 2720 1 0 1.52 0.162 2.05 -3.78 12 0.753 0.123 0.0229 0.0173 0.0304 PRS_PLINK_0.000199526231496888 TRUE 130.1 Lyme disease Both 1 12 1 infectious diseases blue 12, 1 3, 0 3, 0 3, 0 3, 1 -0.28 1.78 0.875 0.058 0.756 0.00658 26.6 5.89 177 0.973 0.012 362 5070 536000 PRS_PLINK_0.000199526231496888 TRUE 131 Protozoan infection Both 4 13 1 infectious diseases blue 13, 4 3, 1 3, 0 3, 2 3, 1 -0.0727 0.801 0.928 0.033 0.93 0.035 3.27 0.309 97.7 0.997 0.001 1.36 0.00296 326 2.48 4.63 0.592 0.228 12 0.0174 1370000 -0.639 178 0.997 0.001 0.528 5.22 4.23 PRS_PLINK_0.000199526231496888 TRUE 132 Infestation (lice, mites) Both 3 25 1 infectious diseases blue 25, 3 7, 0 6, 0 6, 1 6, 2 0.418 0.68 0.538 0.269 1.52 0.459 8.93 1.41 2.32 0.544 0.264 4.09 0.0523 6200 0.733 1.74 0.673 0.172 2.08 0.0135 66.5 PRS_PLINK_0.000199526231496888 TRUE 134 Helminthiases Both 2 9 1 infectious diseases blue 9, 2 3, 0 2, 2 2, 0 2, 0 -0.657 1.48 0.656 0.183 0.518 0.504 0.532 -0.0735 1680 1 0 0.929 0.557 2.9 PRS_PLINK_0.000199526231496888 TRUE 134.1 Intestinal helminthiases Both 0 4 1 infectious diseases blue 4, 0 1 1 1 1 PRS_PLINK_0.000199526231496888 TRUE 136 Other infectious and parasitic diseases Both 82 308 1 infectious diseases blue 308, 82 76, 23 77, 21 77, 25 77, 13 -0.141 0.128 0.273 0.564 0.869 0.675 1.12 -0.0978 0.356 0.784 0.106 0.907 0.453 1.8 -0.0381 0.341 0.911 0.04 0.963 0.496 1.86 -0.657 0.402 0.102 0.99 0.518 0.229 1.12 PRS_PLINK_0.000199526231496888 FALSE 145 Cancer of mouth Both 2 74 2 neoplasms darkcyan 74, 2 19, 2 18, 0 18, 0 19, 0 -0.791 0.572 0.167 0.777 0.453 0.086 1.7 -1.04 1.24 0.403 0.395 0.354 5.83e-06 4.19 -1.22 1.29 0.346 0.46 0.296 8.25e-09 4.09 -0.713 1.39 0.609 0.216 0.49 0.00222 260 PRS_PLINK_0.000199526231496888 TRUE 145.1 Cancer of lip Both 0 3 2 neoplasms darkcyan 3, 0 1 1 1 1 PRS_PLINK_0.000199526231496888 TRUE 145.2 Cancer of tongue Both 0 33 2 neoplasms darkcyan 33, 0 9 8 8 8 PRS_PLINK_0.000199526231496888 TRUE 145.3 Cancer of major salivary glands Both 2 20 2 neoplasms darkcyan 20, 2 5, 2 5, 0 5, 0 5, 0 -0.747 0.905 0.409 0.388 0.474 0.0225 15.4 -0.373 1.59 0.814 0.089 0.689 0.0352 9.3 0.458 3.99 0.909 0.042 1.58 0.000826 1230 -0.526 1.98 0.791 0.102 0.591 0.00863 156 PRS_PLINK_0.000199526231496888 TRUE 145.4 Cancer of the gums Both 0 7 2 neoplasms darkcyan 7, 0 2 2 1 2 PRS_PLINK_0.000199526231496888 TRUE 145.5 Cancer of the mouth floor Both 0 10 2 neoplasms darkcyan 10, 0 3 2 2 3 PRS_PLINK_0.000199526231496888 TRUE 149 Cancer of larynx, pharynx, nasal cavities Both 1 60 2 neoplasms darkcyan 60, 1 15, 1 15, 0 15, 0 15, 0 -0.509 0.547 0.352 0.453 0.601 0.0207 2.41 -0.373 1.25 0.765 0.117 0.689 0.00709 39.4 -0.871 1.29 0.5 0.301 0.418 0.000846 5.4 -0.816 1.23 0.508 0.294 0.442 0.0053 6.57 PRS_PLINK_0.000199526231496888 TRUE 149.1 Cancer of oropharynx Both 1 13 2 neoplasms darkcyan 13, 1 4, 0 3, 1 3, 0 3, 0 -0.425 1.17 0.717 0.144 0.653 0.0324 3.75 1.09 421 0.998 0.001 2.98 1.51 2.5 PRS_PLINK_0.000199526231496888 TRUE 149.2 Cancer of nasopharynx Both 0 12 2 neoplasms darkcyan 12, 0 3 3 3 3 PRS_PLINK_0.000199526231496888 TRUE 149.3 Cancer of hypopharynx Both 0 8 2 neoplasms darkcyan 8, 0 2 2 2 2 PRS_PLINK_0.000199526231496888 TRUE 149.4 Cancer of larynx Both 0 15 2 neoplasms darkcyan 15, 0 4 4 3 4 PRS_PLINK_0.000199526231496888 TRUE 149.5 Hx of malignant neoplasm of oral cavity and pharynx Both 0 25 2 neoplasms darkcyan 25, 0 7 6 6 6 PRS_PLINK_0.000199526231496888 TRUE 149.9 Cancer of of nasal cavities Both 0 14 2 neoplasms darkcyan 14, 0 4 3 3 4 PRS_PLINK_0.000199526231496888 TRUE 150 Cancer of esophagus Both 0 22 2 neoplasms darkcyan 22, 0 6 5 5 6 PRS_PLINK_0.000199526231496888 TRUE 151 Cancer of stomach Both 2 17 2 neoplasms darkcyan 17, 2 5, 0 4, 0 4, 1 4, 1 -0.147 0.996 0.883 0.054 0.864 0.0568 23.6 0.118 2.16 0.957 0.019 1.13 0.0361 30.2 6.02e-14 8.6 1 0 1 0.000517 1750 PRS_PLINK_0.000199526231496888 TRUE 153 Colorectal cancer Both 8 73 2 neoplasms darkcyan 73, 8 19, 4 18, 3 18, 0 18, 1 -0.843 0.535 0.115 0.938 0.431 0.0518 1.31 0.463 1.1 0.674 0.171 1.59 0.168 30.6 -2.18 1.75 0.212 0.673 0.113 5.48e-08 2.89 -1.02 1.45 0.482 0.317 0.361 8.53e-08 7.73 PRS_PLINK_0.000199526231496888 TRUE 153.2 Colon cancer Both 3 57 2 neoplasms darkcyan 57, 3 15, 1 14, 2 14, 0 14, 0 -0.471 0.602 0.434 0.362 0.624 0.0962 3.05 0.645 1.42 0.65 0.187 1.91 0.0464 51.4 -0.417 1.56 0.789 0.103 0.659 0.00239 19 0.145 1.47 0.922 0.035 1.16 0.00127 372 PRS_PLINK_0.000199526231496888 TRUE 153.3 Malignant neoplasm of rectum, rectosigmoid junction, and anus Both 6 45 2 neoplasms darkcyan 45, 6 12, 3 11, 2 11, 0 11, 1 -0.77 0.583 0.187 0.729 0.463 0.0833 1.46 0.724 1.16 0.533 0.273 2.06 0.144 59.7 -1.35 1.59 0.395 0.403 0.258 1.01e-08 5.92 -0.769 1.43 0.591 0.228 0.464 3.45e-06 11 PRS_PLINK_0.000199526231496888 TRUE 155 Cancer of liver and intrahepatic bile duct Both 1 28 2 neoplasms darkcyan 28, 1 7, 0 7, 1 7, 0 7, 0 -0.291 0.909 0.749 0.126 0.747 0.00252 12 0.95 2.02 0.639 0.195 2.59 0.0129 14800 PRS_PLINK_0.000199526231496888 TRUE 155.1 Malignant neoplasm of liver, primary Both 1 16 2 neoplasms darkcyan 16, 1 4, 1 4, 0 4, 0 4, 0 -0.902 1.21 0.457 0.341 0.406 0.00112 4.46 -2.44 4.38 0.578 0.238 0.0874 6.5e-05 29.3 -0.777 127 0.995 0.002 0.46 0.438 0.483 -1.67 4.86 0.731 0.136 0.188 2.03e-05 137 PRS_PLINK_0.000199526231496888 TRUE 157 Pancreatic cancer Both 2 24 2 neoplasms darkcyan 24, 2 6, 0 6, 0 6, 0 6, 2 0.0195 0.75 0.979 0.009 1.02 0.0758 17.4 1.09 2.69 0.685 0.164 2.98 0.00469 9370 PRS_PLINK_0.000199526231496888 TRUE 158 Neoplasm of unspecified nature of digestive system Both 16 98 2 neoplasms darkcyan 98, 16 25, 5 24, 4 24, 1 25, 6 0.0534 0.296 0.856 0.067 1.05 0.583 1.92 -0.617 0.914 0.5 0.301 0.539 0.0651 3.04 -1.57 1.07 0.144 0.843 0.209 0.0103 1.56 0.286 0.715 0.689 0.161 1.33 0.345 5.43 PRS_PLINK_0.000199526231496888 TRUE 159 Malignant neoplasm of other and ill-defined sites within the digestive organs and peritoneum Both 9 105 2 neoplasms darkcyan 105, 9 27, 4 26, 1 26, 3 26, 1 -0.0835 0.346 0.809 0.092 0.92 0.44 1.88 -1.74 1.68 0.302 0.52 0.176 1.17e-05 5.46 -0.599 0.836 0.474 0.324 0.55 0.0926 2.76 -0.552 1.01 0.584 0.234 0.576 0.0457 5.29 PRS_PLINK_0.000199526231496888 TRUE 159.2 Malignant neoplasm of small intestine, including duodenum Both 1 14 2 neoplasms darkcyan 14, 1 4, 0 3, 0 3, 0 4, 1 -0.0256 1.75 0.988 0.005 0.975 0.0226 73 0.0552 781 1 0 1.06 0.839 1.63 PRS_PLINK_0.000199526231496888 TRUE 159.3 Malignant neoplasm of gallbladder and extrahepatic bile ducts Both 0 7 2 neoplasms darkcyan 7, 0 2 2 1 2 PRS_PLINK_0.000199526231496888 TRUE 159.4 Malignant neoplasm of retroperitoneum and peritoneum Both 0 28 2 neoplasms darkcyan 28, 0 7 7 7 7 PRS_PLINK_0.000199526231496888 TRUE 164 Cancer of intrathoracic organs Both 2 10 2 neoplasms darkcyan 10, 2 3, 2 2, 0 2, 0 3, 0 0.379 1.58 0.81 0.091 1.46 0.0992 86.5 -3.8 225 0.986 0.006 0.0223 0.0168 0.0285 -1.03 96.4 0.992 0.004 0.358 0.0178 3.7 0.924 3.87 0.811 0.091 2.52 0.00632 1080 PRS_PLINK_0.000199526231496888 TRUE 165 Cancer within the respiratory system Both 0 71 2 neoplasms darkcyan 71, 0 18 18 17 18 PRS_PLINK_0.000199526231496888 TRUE 165.1 Cancer of bronchus; lung Both 0 59 2 neoplasms darkcyan 59, 0 15 15 14 15 PRS_PLINK_0.000199526231496888 TRUE 170 Cancer of bone and connective tissue Both 5 125 2 neoplasms darkcyan 125, 5 31, 1 31, 1 31, 2 31, 1 0.335 0.405 0.408 0.39 1.4 0.585 3.87 0.0279 1.02 0.978 0.01 1.03 0.073 27.7 0.994 0.992 0.317 0.499 2.7 0.339 48.2 0.254 1.01 0.801 0.096 1.29 0.116 22.7 PRS_PLINK_0.000199526231496888 TRUE 170.1 Bone cancer Both 3 49 2 neoplasms darkcyan 49, 3 13, 0 12, 2 12, 1 12, 0 0.155 0.581 0.789 0.103 1.17 0.258 10.2 1.35 1.38 0.327 0.485 3.85 0.328 273000 0.683 1.36 0.616 0.211 1.98 0.079 74.1 PRS_PLINK_0.000199526231496888 TRUE 170.2 Cancer of connective tissue Both 2 92 2 neoplasms darkcyan 92, 2 22, 0 23, 1 23, 0 23, 1 0.611 0.532 0.251 0.6 1.84 0.55 10.6 0.398 1.31 0.761 0.119 1.49 0.0322 215 0.901 1.11 0.418 0.379 2.46 0.208 264 PRS_PLINK_0.000199526231496888 TRUE 172 Skin cancer Both 43 330 2 neoplasms darkcyan 330, 43 82, 13 82, 8 82, 7 83, 15 0.144 0.17 0.397 0.401 1.16 0.825 1.63 -0.285 0.478 0.552 0.258 0.752 0.282 1.93 -0.503 0.486 0.301 0.521 0.605 0.219 1.57 0.282 0.446 0.527 0.279 1.33 0.555 3.22 PRS_PLINK_0.000199526231496888 TRUE 172.1 Melanomas of skin, dx or hx Both 32 267 2 neoplasms darkcyan 267, 32 67, 9 67, 7 66, 4 67, 12 0.171 0.193 0.376 0.425 1.19 0.807 1.75 -0.128 0.523 0.807 0.093 0.88 0.304 2.49 -0.801 0.597 0.18 0.745 0.449 0.122 1.44 0.388 0.496 0.435 0.362 1.47 0.559 3.99 PRS_PLINK_0.000199526231496888 TRUE 172.11 Melanomas of skin Both 10 204 2 neoplasms darkcyan 204, 10 51, 3 51, 1 51, 1 51, 5 0.314 0.292 0.281 0.551 1.37 0.724 2.57 -0.946 0.875 0.28 0.553 0.388 0.037 2.51 -0.879 0.847 0.299 0.524 0.415 0.043 2.48 0.647 0.672 0.336 0.474 1.91 0.49 8.54 PRS_PLINK_0.000199526231496888 TRUE 172.2 Other non-epithelial cancer of skin Both 33 264 2 neoplasms darkcyan 264, 33 65, 10 66, 8 66, 4 66, 11 0.0946 0.193 0.624 0.205 1.1 0.748 1.62 -0.0149 0.518 0.977 0.01 0.985 0.347 2.77 -0.686 0.584 0.24 0.619 0.504 0.141 1.58 0.24 0.518 0.643 0.192 1.27 0.457 3.57 PRS_PLINK_0.000199526231496888 TRUE 172.21 Basal cell carcinoma Both 20 158 2 neoplasms darkcyan 158, 20 40, 7 39, 3 39, 4 40, 6 0.045 0.239 0.851 0.07 1.05 0.644 1.69 -0.468 0.659 0.477 0.321 0.626 0.146 2.25 -0.544 0.641 0.396 0.402 0.581 0.149 1.99 -0.0325 0.624 0.958 0.018 0.968 0.27 3.27 PRS_PLINK_0.000199526231496888 TRUE 172.22 Squamous cell carcinoma Both 11 84 2 neoplasms darkcyan 84, 11 21, 2 21, 4 21, 0 21, 5 0.31 0.307 0.312 0.506 1.36 0.749 2.68 0.459 0.82 0.576 0.24 1.58 0.322 9.1 -1.79 1.43 0.209 0.68 0.166 0.000993 2.45 1.12 0.891 0.21 0.679 3.06 0.583 30.6 PRS_PLINK_0.000199526231496888 TRUE 172.3 Carcinoma in situ of skin Both 11 71 2 neoplasms darkcyan 71, 11 18, 3 18, 2 17, 1 18, 5 0.338 0.371 0.362 0.441 1.4 0.676 3.15 -0.442 0.883 0.616 0.21 0.642 0.0972 3.45 -0.806 1.07 0.451 0.346 0.447 0.0417 3.35 0.915 0.922 0.321 0.494 2.5 0.47 18.4 PRS_PLINK_0.000199526231496888 TRUE 173 Neoplasm of uncertain behavior of skin Both 27 159 2 neoplasms darkcyan 159, 27 40, 5 40, 6 39, 8 40, 8 0.11 0.215 0.607 0.217 1.12 0.729 1.72 0.342 0.645 0.596 0.225 1.41 0.39 5.41 0.56 0.606 0.355 0.449 1.75 0.543 6.32 0.439 0.592 0.458 0.339 1.55 0.492 5.25 PRS_PLINK_0.000199526231496888 TRUE 174 Breast cancer Both 31 199 2 neoplasms darkcyan 199, 31 50, 9 50, 9 49, 11 50, 2 -0.402 0.22 0.0676 1.17 0.669 0.427 1.03 -0.136 0.576 0.814 0.09 0.873 0.278 2.75 -0.0758 0.571 0.894 0.048 0.927 0.3 2.82 -1.34 0.789 0.0903 1.044 0.263 0.0428 1.18 PRS_PLINK_0.000199526231496888 TRUE 174.1 Breast cancer [female] Female 30 193 2 neoplasms darkcyan 193, 30 49, 8 48, 9 48, 11 48, 2 -0.359 0.223 0.108 0.966 0.699 0.444 1.08 0.0192 0.584 0.974 0.012 1.02 0.32 3.34 0.0365 0.575 0.949 0.023 1.04 0.334 3.21 -1.22 0.789 0.122 0.915 0.295 0.0479 1.33 PRS_PLINK_0.000199526231496888 TRUE 174.11 Malignant neoplasm of female breast Female 29 189 2 neoplasms darkcyan 189, 29 48, 7 47, 9 47, 11 47, 2 -0.313 0.227 0.168 0.775 0.731 0.462 1.14 0.133 0.621 0.831 0.081 1.14 0.339 4.03 0.125 0.613 0.838 0.077 1.13 0.337 3.87 -1.19 0.837 0.156 0.806 0.305 0.0446 1.54 PRS_PLINK_0.000199526231496888 TRUE 174.3 Neoplasm of uncertain behavior of breast Both 3 21 2 neoplasms darkcyan 21, 3 6, 1 5, 0 5, 1 5, 1 -0.0732 0.958 0.939 0.027 0.929 0.0288 6.62 -0.0721 1.82 0.968 0.014 0.93 6.55e-05 23.1 -0.0895 1.55 0.954 0.02 0.914 0.0248 14.1 0.743 2.07 0.72 0.143 2.1 0.0234 782 PRS_PLINK_0.000199526231496888 TRUE 175 Acquired absence of breast Female 12 85 2 neoplasms darkcyan 85, 12 22, 3 21, 3 21, 4 21, 2 -0.218 0.363 0.548 0.261 0.804 0.383 1.57 0.364 1.25 0.771 0.113 1.44 0.117 34.7 0.561 0.907 0.536 0.271 1.75 0.296 12.8 -0.256 1.21 0.832 0.08 0.774 0.0536 19.3 PRS_PLINK_0.000199526231496888 TRUE 180 Cervical cancer and dysplasia Female 59 137 2 neoplasms darkcyan 137, 59 35, 13 34, 14 34, 24 34, 8 -0.121 0.17 0.475 0.323 0.886 0.637 1.23 -0.211 0.507 0.678 0.169 0.81 0.304 2.12 0.61 0.452 0.177 0.751 1.84 0.787 4.4 -0.268 0.59 0.65 0.187 0.765 0.236 2.37 PRS_PLINK_0.000199526231496888 FALSE 180.1 Cervical cancer Female 5 46 2 neoplasms darkcyan 46, 5 12, 1 11, 0 11, 2 12, 2 0.176 0.537 0.743 0.129 1.19 0.352 4.72 -0.699 1.72 0.684 0.165 0.497 0.00117 13.8 -0.0284 1.19 0.981 0.008 0.972 0.0804 11.9 1.49 1.46 0.305 0.516 4.46 0.352 426 PRS_PLINK_0.000199526231496888 TRUE 180.3 Cervical intraepithelial neoplasia [CIN] [Cervical dysplasia] Female 56 126 2 neoplasms darkcyan 126, 56 32, 14 31, 13 31, 22 32, 7 -0.145 0.173 0.403 0.394 0.865 0.618 1.21 -0.264 0.501 0.599 0.223 0.768 0.291 1.97 0.464 0.449 0.301 0.521 1.59 0.684 3.76 -0.468 0.606 0.44 0.357 0.626 0.186 1.98 PRS_PLINK_0.000199526231496888 FALSE 182 Malignant neoplasm of uterus Female 4 56 2 neoplasms darkcyan 56, 4 14, 2 14, 0 14, 1 14, 1 0.156 0.631 0.804 0.095 1.17 0.294 8.54 -1.01 1.5 0.502 0.3 0.365 0.00075 8.04 -0.0822 1.23 0.947 0.024 0.921 0.0665 26.4 0.261 1.57 0.868 0.062 1.3 0.0097 23100 PRS_PLINK_0.000199526231496888 TRUE 184 Cancer of other female genital organs Female 12 111 2 neoplasms darkcyan 111, 12 28, 4 28, 2 27, 2 28, 4 -0.184 0.348 0.597 0.224 0.832 0.414 1.63 -0.0876 1.03 0.932 0.031 0.916 0.0876 7.32 0.308 0.895 0.731 0.136 1.36 0.21 9.22 0.132 0.991 0.894 0.049 1.14 0.146 8.48 PRS_PLINK_0.000199526231496888 TRUE 184.1 Malignant neoplasm of ovary and other uterine adnexa Female 7 49 2 neoplasms darkcyan 49, 7 13, 2 12, 2 12, 1 12, 2 -0.419 0.523 0.423 0.374 0.658 0.172 1.78 0.834 1.53 0.586 0.232 2.3 0.108 1100 -0.0295 1.39 0.983 0.007 0.971 0.00215 61.2 -1.18 1.75 0.499 0.302 0.307 9.61e-05 7.26 PRS_PLINK_0.000199526231496888 TRUE 184.11 Malignant neoplasm of ovary Female 7 40 2 neoplasms darkcyan 40, 7 10, 2 10, 2 10, 1 10, 2 -0.17 0.594 0.775 0.111 0.844 0.198 2.71 1.22 1.92 0.526 0.279 3.39 0.0369 110 -0.0375 1.4 0.979 0.009 0.963 0.0835 20.7 -0.379 1.53 0.805 0.094 0.685 0.00141 14.1 PRS_PLINK_0.000199526231496888 TRUE 184.2 Cancer of other female genital organs (excluding uterus and ovary) Female 5 60 2 neoplasms darkcyan 60, 5 15, 1 15, 1 15, 1 15, 2 -0.104 0.664 0.875 0.058 0.901 0.188 7.92 -0.209 1.47 0.887 0.052 0.812 0.00444 17 -0.158 1.52 0.917 0.037 0.854 0.00288 158 0.0541 1.73 0.975 0.011 1.06 0.00432 607 PRS_PLINK_0.000199526231496888 TRUE 185 Cancer of prostate Male 5 41 2 neoplasms darkcyan 41, 5 11, 2 10, 1 10, 2 10, 0 -0.687 0.576 0.233 0.632 0.503 0.0994 1.41 -0.973 1.46 0.505 0.297 0.378 0.000404 10.7 -0.191 1.23 0.877 0.057 0.826 0.0462 13.7 -2.03 1.86 0.276 0.56 0.131 4.12e-06 3.18 PRS_PLINK_0.000199526231496888 TRUE 187 Cancer of other male genital organs Male 0 7 2 neoplasms darkcyan 7, 0 2 2 1 2 PRS_PLINK_0.000199526231496888 TRUE 187.1 Malignant neoplasm of unspecified male genital organ Male 0 2 2 neoplasms darkcyan 2, 0 1 1 1 1 PRS_PLINK_0.000199526231496888 TRUE 187.2 Malignant neoplasm of testis Male 0 4 2 neoplasms darkcyan 4, 0 1 1 1 1 PRS_PLINK_0.000199526231496888 TRUE 189 Cancer of urinary organs (incl. kidney and bladder) Both 8 140 2 neoplasms darkcyan 140, 8 35, 2 35, 2 35, 0 35, 4 0.418 0.375 0.265 0.576 1.52 0.69 3.57 -1.19 1.07 0.269 0.571 0.306 0.0136 3.12 -1.43 1.18 0.225 0.648 0.24 0.00255 2.87 0.46 0.876 0.599 0.222 1.58 0.285 12 PRS_PLINK_0.000199526231496888 TRUE 189.1 Cancer of kidney and renal pelvis Both 6 89 2 neoplasms darkcyan 89, 6 23, 1 22, 2 22, 0 22, 3 0.26 0.474 0.583 0.234 1.3 0.433 4.53 -0.51 1.44 0.724 0.14 0.601 0.000928 262 -0.57 1.38 0.68 0.167 0.566 0.000485 31.4 0.746 1.15 0.516 0.288 2.11 0.169 80.2 PRS_PLINK_0.000199526231496888 TRUE 189.11 Malignant neoplasm of kidney, except pelvis Both 5 73 2 neoplasms darkcyan 73, 5 19, 2 18, 0 18, 0 18, 3 0.0656 0.471 0.889 0.051 1.07 0.367 3.22 -1.09 1.46 0.454 0.343 0.336 0.000141 8.96 -1.36 1.51 0.37 0.432 0.258 0.00091 4.41 -0.399 1.13 0.724 0.14 0.671 0.0594 6.56 PRS_PLINK_0.000199526231496888 TRUE 189.12 Malignant neoplasm of renal pelvis Both 0 12 2 neoplasms darkcyan 12, 0 3 3 3 3 PRS_PLINK_0.000199526231496888 TRUE 189.2 Cancer of bladder Both 2 78 2 neoplasms darkcyan 78, 2 20, 1 19, 0 19, 0 20, 1 -0.32 0.555 0.564 0.249 0.726 0.109 3.16 -0.693 1.19 0.561 0.251 0.5 0.00102 8.49 -0.446 1.27 0.725 0.14 0.64 0.000967 67.5 -0.375 1.12 0.739 0.132 0.688 0.0189 8.9 PRS_PLINK_0.000199526231496888 TRUE 189.21 Malignant neoplasm of bladder Both 1 69 2 neoplasms darkcyan 69, 1 18, 0 17, 0 17, 0 17, 1 0.273 0.566 0.63 0.201 1.31 0.172 25.6 0.169 1.28 0.895 0.048 1.18 0.0222 707 PRS_PLINK_0.000199526231496888 TRUE 189.4 Malignant neoplasm of other urinary organs Both 0 33 2 neoplasms darkcyan 33, 0 9 8 8 8 PRS_PLINK_0.000199526231496888 TRUE 190 Cancer of eye Both 0 5 2 neoplasms darkcyan 5, 0 2 1 1 1 PRS_PLINK_0.000199526231496888 TRUE 191 Manlignant and unknown neoplasms of brain and nervous system Both 8 75 2 neoplasms darkcyan 75, 8 19, 2 19, 2 18, 1 19, 3 0.365 0.468 0.436 0.361 1.44 0.576 4.35 -0.736 1.44 0.609 0.215 0.479 0.000184 13.5 0.422 1.25 0.735 0.133 1.52 0.0903 31.6 2.89 1.88 0.125 0.904 18 0.682 415000 PRS_PLINK_0.000199526231496888 TRUE 191.1 Cancer of brain and nervous system Both 2 58 2 neoplasms darkcyan 58, 2 15, 0 14, 1 14, 0 15, 1 0.338 0.697 0.628 0.202 1.4 0.219 17 0.712 1.35 0.599 0.223 2.04 0.0743 638 0.582 1.28 0.65 0.187 1.79 0.107 107 PRS_PLINK_0.000199526231496888 TRUE 191.11 Cancer of brain Both 2 58 2 neoplasms darkcyan 58, 2 15, 0 14, 1 14, 0 15, 1 0.921 0.754 0.222 0.653 2.51 0.436 80 1.1 1.31 0.399 0.399 3.01 0.198 3510 0.859 1.37 0.53 0.276 2.36 0.169 345 PRS_PLINK_0.000199526231496888 TRUE 193 Thyroid cancer Both 13 101 2 neoplasms darkcyan 101, 13 25, 3 25, 3 25, 4 25, 3 -0.0824 0.295 0.78 0.108 0.921 0.512 1.69 0.407 0.872 0.64 0.194 1.5 0.263 11.1 0.306 0.828 0.712 0.147 1.36 0.273 8.07 -0.818 1.11 0.462 0.336 0.441 0.0357 3.68 PRS_PLINK_0.000199526231496888 TRUE 194 Cancer of other endocrine glands Both 11 60 2 neoplasms darkcyan 60, 11 14, 2 15, 3 15, 3 15, 3 0.234 0.405 0.564 0.249 1.26 0.599 2.87 0.755 1.13 0.504 0.298 2.13 0.279 37.1 0.973 1.14 0.393 0.405 2.65 0.286 53.5 1.41 1.45 0.332 0.479 4.1 0.282 158 PRS_PLINK_0.000199526231496888 TRUE 195 Cancer, suspected or other Both 97 308 2 neoplasms darkcyan 308, 97 76, 23 77, 31 77, 19 77, 24 0.0143 0.126 0.909 0.041 1.01 0.795 1.3 0.386 0.357 0.279 0.554 1.47 0.743 2.97 -0.218 0.394 0.581 0.236 0.804 0.37 1.73 0.0376 0.38 0.921 0.036 1.04 0.499 2.17 PRS_PLINK_0.000199526231496888 FALSE 195.1 Malignant neoplasm, other Both 96 308 2 neoplasms darkcyan 308, 96 76, 23 77, 30 77, 19 77, 24 0.0148 0.126 0.907 0.043 1.01 0.794 1.3 0.349 0.361 0.334 0.477 1.42 0.71 2.89 -0.218 0.394 0.581 0.236 0.804 0.37 1.73 0.0376 0.38 0.921 0.036 1.04 0.499 2.17 PRS_PLINK_0.000199526231496888 FALSE 195.3 Malignant neoplasm of head, face, and neck Both 1 57 2 neoplasms darkcyan 57, 1 15, 0 14, 1 14, 0 14, 0 0.443 0.637 0.486 0.313 1.56 0.301 21.2 1.29 1.37 0.343 0.464 3.65 0.244 326 PRS_PLINK_0.000199526231496888 TRUE 196 Radiotherapy Both 9 144 2 neoplasms darkcyan 144, 9 35, 3 36, 2 36, 3 36, 1 -0.136 0.321 0.671 0.173 0.872 0.44 1.73 -0.559 0.915 0.541 0.267 0.572 0.0626 3.91 -0.0561 0.846 0.947 0.024 0.945 0.149 5.89 -1.53 1.28 0.233 0.633 0.216 0.172 2.63 PRS_PLINK_0.000199526231496888 TRUE 197 Chemotherapy Both 26 279 2 neoplasms darkcyan 279, 26 69, 7 70, 11 69, 4 70, 4 -0.314 0.21 0.136 0.867 0.731 0.476 1.11 0.367 0.535 0.492 0.308 1.44 0.504 4.37 -0.94 0.689 0.173 0.763 0.391 0.082 1.53 -0.569 0.645 0.378 0.423 0.566 0.139 2.05 PRS_PLINK_0.000199526231496888 TRUE 198 Secondary malignant neoplasm Both 19 281 2 neoplasms darkcyan 281, 19 70, 4 70, 4 70, 3 70, 8 0.221 0.231 0.338 0.472 1.25 0.791 1.99 0.371 0.746 0.619 0.208 1.45 0.303 7.35 0.0901 0.795 0.91 0.041 1.09 0.19 6.2 0.524 0.65 0.42 0.376 1.69 0.475 6.71 PRS_PLINK_0.000199526231496888 TRUE 198.1 Secondary malignancy of lymph nodes Both 10 240 2 neoplasms darkcyan 240, 10 59, 1 60, 3 60, 3 60, 3 0.193 0.285 0.499 0.302 1.21 0.672 2.22 0.661 0.839 0.431 0.366 1.94 0.303 19.5 1.32 1.03 0.199 0.701 3.76 0.457 80 0.056 1.08 0.959 0.018 1.06 0.0445 37.4 PRS_PLINK_0.000199526231496888 TRUE 198.2 Secondary malignancy of respiratory organs Both 1 74 2 neoplasms darkcyan 74, 1 19, 1 18, 0 18, 0 19, 0 -0.713 0.697 0.306 0.514 0.49 0.00432 3.49 -1.25 1.35 0.354 0.452 0.287 0.00179 6.53 -1.12 1.36 0.41 0.387 0.326 0.00299 16.4 -1.32 1.35 0.33 0.481 0.268 0.00159 7.01 PRS_PLINK_0.000199526231496888 TRUE 198.3 Secondary malignant neoplasm of digestive systems Both 4 57 2 neoplasms darkcyan 57, 4 15, 2 14, 0 14, 1 14, 1 -0.803 0.615 0.192 0.718 0.448 0.0862 1.65 -1.76 1.5 0.241 0.619 0.173 0.000771 2.05 -0.773 1.3 0.553 0.257 0.462 0.00215 6.91 -0.854 1.51 0.573 0.242 0.426 0.0163 9.38 PRS_PLINK_0.000199526231496888 TRUE 198.4 Secondary malignant neoplasm of liver Both 1 57 2 neoplasms darkcyan 57, 1 15, 0 14, 0 14, 1 14, 0 -0.0303 0.525 0.954 0.02 0.97 0.244 4.01 0.945 1.33 0.479 0.32 2.57 0.134 431 PRS_PLINK_0.000199526231496888 TRUE 198.5 Secondary malignancy of brain/spine Both 4 46 2 neoplasms darkcyan 46, 4 12, 3 11, 0 11, 0 12, 1 -0.588 0.576 0.307 0.513 0.555 0.104 1.65 -1.03 1.52 0.499 0.302 0.357 1e-04 12.3 -0.97 1.44 0.5 0.301 0.379 0.000648 8.03 -2.22 1.93 0.25 0.602 0.108 1.08e-07 3.22 PRS_PLINK_0.000199526231496888 TRUE 198.6 Secondary malignancy of bone Both 1 59 2 neoplasms darkcyan 59, 1 15, 0 15, 1 14, 0 15, 0 -0.266 0.653 0.684 0.165 0.767 0.032 4.92 0.586 1.35 0.665 0.177 1.8 0.0132 123 PRS_PLINK_0.000199526231496888 TRUE 198.7 Secondary malignant neoplasm of skin Both 1 20 2 neoplasms darkcyan 20, 1 5, 1 5, 0 5, 0 5, 0 -0.26 0.68 0.702 0.154 0.771 0.198 3.81 -0.813 1.77 0.645 0.19 0.443 0.0142 5.99 0.516 2.26 0.82 0.086 1.68 0.0222 4170 0.307 2.56 0.905 0.043 1.36 0.021 355 PRS_PLINK_0.000199526231496888 TRUE 199 Neoplasm of uncertain behavior Both 54 305 2 neoplasms darkcyan 305, 54 76, 12 76, 19 76, 11 76, 12 -0.00492 0.157 0.975 0.011 0.995 0.731 1.35 0.401 0.437 0.358 0.446 1.49 0.64 3.6 -0.144 0.474 0.761 0.118 0.866 0.331 2.22 -0.0797 0.479 0.868 0.062 0.923 0.357 2.37 PRS_PLINK_0.000199526231496888 FALSE 199.4 Neurofibromatosis Both 1 6 2 neoplasms darkcyan 6, 1 2, 1 1, 0 1, 0 2, 0 0.149 520 1 0 1.16 1.45 1.02 0.179 2310 1 0 1.2 0.499 1.5 0.17 4430 1 0 1.18 0.624 4.66 -0.825 1960 1 0 0.438 1.69e-06 510000 PRS_PLINK_0.000199526231496888 TRUE 200 Myeloproliferative disease Both 12 89 2 neoplasms darkcyan 89, 12 22, 6 22, 0 22, 1 22, 5 -0.0628 0.275 0.819 0.087 0.939 0.544 1.63 -3.03 1.58 0.0548 1.261 0.0483 0.000161 0.773 -0.929 0.924 0.315 0.502 0.395 0.0407 2.23 -0.395 0.779 0.612 0.213 0.674 0.147 2.98 PRS_PLINK_0.000199526231496888 TRUE 200.1 Polycythemia vera Both 4 13 2 neoplasms darkcyan 13, 4 4, 3 3, 0 3, 0 3, 1 -0.843 1.08 0.437 0.36 0.43 0.0358 2.26 0.282 5.3 0.958 0.019 1.33 0.000811 18700 0.0959 947 1 0 1.1 0.906 2.95 -1.61 3.41 0.636 0.197 0.199 0.000351 36.8 PRS_PLINK_0.000199526231496888 TRUE 201 Hodgkin's disease Both 1 15 2 neoplasms darkcyan 15, 1 4, 0 4, 0 3, 1 4, 0 -0.00356 0.925 0.997 0.001 0.996 0.0987 9.99 0.0509 227 1 0 1.05 0.731 2.48 PRS_PLINK_0.000199526231496888 TRUE 202 Cancer of other lymphoid, histiocytic tissue Both 13 110 2 neoplasms darkcyan 110, 13 28, 2 27, 3 27, 5 28, 3 0.349 0.302 0.248 0.605 1.42 0.777 2.68 0.0634 0.892 0.943 0.025 1.07 0.152 9.12 1.18 0.92 0.2 0.699 3.25 0.576 26.8 0.367 0.948 0.699 0.156 1.44 0.186 12.7 PRS_PLINK_0.000199526231496888 TRUE 202.2 Non-Hodgkins lymphoma Both 12 95 2 neoplasms darkcyan 95, 12 24, 2 24, 4 23, 3 24, 3 0.283 0.311 0.363 0.44 1.33 0.718 2.53 0.834 0.949 0.38 0.42 2.3 0.349 26.4 1.05 1.1 0.339 0.47 2.87 0.336 51.9 0.407 0.969 0.674 0.171 1.5 0.208 13.1 PRS_PLINK_0.000199526231496888 TRUE 202.21 Nodular lymphoma Both 7 59 2 neoplasms darkcyan 59, 7 15, 1 15, 2 14, 1 15, 3 0.137 0.361 0.704 0.153 1.15 0.544 2.5 1.3 1.44 0.366 0.436 3.67 0.24 1290 0.0326 1.4 0.981 0.008 1.03 0.0102 44 0.432 1.09 0.691 0.161 1.54 0.124 27.8 PRS_PLINK_0.000199526231496888 TRUE 202.22 Reticulosarcoma Both 1 13 2 neoplasms darkcyan 13, 1 4, 0 3, 0 3, 0 3, 1 0.261 0.78 0.738 0.132 1.3 0.00245 18.7 -0.412 4050000 1 0 0.663 0.0629 1.04 PRS_PLINK_0.000199526231496888 TRUE 202.24 Large cell lymphoma Both 1 11 2 neoplasms darkcyan 11, 1 3, 0 3, 0 2, 0 3, 1 -0.0198 0.872 0.982 0.008 0.98 0.00791 7.43 -0.0827 5670000 1 0 0.921 0.0234 86.6 PRS_PLINK_0.000199526231496888 TRUE 204 Leukemia Both 3 38 2 neoplasms darkcyan 38, 3 10, 1 9, 0 9, 0 10, 2 -0.117 0.512 0.819 0.087 0.889 0.304 3.68 -1.22 1.49 0.414 0.383 0.295 6.01e-05 4.16 -1.23 1.56 0.43 0.366 0.293 4.9e-05 4.87 -0.234 1.44 0.871 0.06 0.791 0.00955 22.7 PRS_PLINK_0.000199526231496888 TRUE 204.1 Lymphoid leukemia Both 1 11 2 neoplasms darkcyan 11, 1 3, 0 3, 0 2, 0 3, 1 -0.416 1.41 0.768 0.114 0.66 0.046 15.4 0.895 7250000 1 0 2.45 0.00086 2250 PRS_PLINK_0.000199526231496888 TRUE 204.11 Lymphoid leukemia, acute Both 0 2 2 neoplasms darkcyan 2, 0 1 1 1 1 PRS_PLINK_0.000199526231496888 TRUE 204.12 Lymphoid leukemia, chronic Both 1 6 2 neoplasms darkcyan 6, 1 2, 0 1, 0 1, 0 2, 1 -0.346 5120 1 0 0.708 0.685 1.45 -0.495 9020 1 0 0.609 0.00724 4.74 PRS_PLINK_0.000199526231496888 TRUE 204.2 Myeloid leukemia Both 0 14 2 neoplasms darkcyan 14, 0 4 3 3 4 PRS_PLINK_0.000199526231496888 TRUE 204.21 Myeloid leukemia, acute Both 0 6 2 neoplasms darkcyan 6, 0 2 1 1 2 PRS_PLINK_0.000199526231496888 TRUE 204.22 Myeloid leukemia, chronic Both 0 6 2 neoplasms darkcyan 6, 0 2 1 1 2 PRS_PLINK_0.000199526231496888 TRUE 204.4 Multiple myeloma Both 1 9 2 neoplasms darkcyan 9, 1 3, 0 2, 0 2, 0 2, 1 -1.53 16.9 0.928 0.033 0.216 2.85e-05 1330 -0.144 2080 1 0 0.866 0.476 1.32 PRS_PLINK_0.000199526231496888 TRUE 208 Benign neoplasm of colon Both 116 326 2 neoplasms darkcyan 326, 116 81, 32 81, 33 81, 26 82, 25 -0.17 0.122 0.163 0.788 0.844 0.665 1.07 0.156 0.333 0.639 0.195 1.17 0.616 2.24 -0.169 0.357 0.635 0.197 0.844 0.419 1.69 -0.254 0.356 0.475 0.323 0.776 0.387 1.54 PRS_PLINK_0.000199526231496888 FALSE 209 Neuroendocrine tumors Both 4 9 2 neoplasms darkcyan 9, 4 3, 0 2, 2 2, 1 2, 1 1.08 1.63 0.506 0.295 2.95 0.266 54.5 -0.26 687 1 0 0.771 0.144 3.15 -0.149 232 0.999 0 0.861 0.137 5.89 0.0716 364 1 0 1.07 0.582 3.53 PRS_PLINK_0.000199526231496888 TRUE 210 Benign neoplasm of lip, oral cavity, and pharynx Both 15 150 2 neoplasms darkcyan 150, 15 38, 3 37, 6 37, 3 38, 3 -0.123 0.289 0.669 0.175 0.884 0.482 1.6 0.57 0.709 0.422 0.375 1.77 0.442 8.32 0.0229 0.753 0.976 0.011 1.02 0.2 5.28 -0.23 0.825 0.78 0.108 0.795 0.123 4.45 PRS_PLINK_0.000199526231496888 TRUE 211 Benign neoplasm of other parts of digestive system Both 112 326 2 neoplasms darkcyan 326, 112 81, 24 81, 35 81, 22 82, 31 0.0749 0.116 0.518 0.286 1.08 0.861 1.35 0.4 0.313 0.201 0.696 1.49 0.817 2.76 -0.157 0.346 0.65 0.187 0.855 0.433 1.68 0.301 0.327 0.358 0.446 1.35 0.719 2.56 PRS_PLINK_0.000199526231496888 FALSE 212 Benign neoplasm of respiratory and intrathoracic organs Both 6 142 2 neoplasms darkcyan 142, 6 36, 2 35, 1 35, 3 36, 0 -0.183 0.357 0.608 0.216 0.832 0.347 1.85 -0.649 1.02 0.525 0.28 0.523 0.0208 5.08 0.297 0.779 0.703 0.153 1.35 0.246 7.99 -0.977 1.01 0.333 0.477 0.376 0.0042 3.4 PRS_PLINK_0.000199526231496888 TRUE 213 Benign neoplasm of bone and articular cartilage Both 10 94 2 neoplasms darkcyan 94, 10 24, 3 23, 2 23, 5 24, 0 -0.638 0.447 0.153 0.815 0.528 0.187 1.27 -0.439 1.28 0.731 0.136 0.644 0.016 17.1 -0.422 1.08 0.696 0.158 0.656 0.0569 5.35 -1.1 1.43 0.441 0.355 0.332 8.01e-07 6.84 PRS_PLINK_0.000199526231496888 TRUE 214 Lipoma Both 28 113 2 neoplasms darkcyan 113, 28 29, 10 28, 3 28, 5 28, 10 0.0753 0.262 0.773 0.112 1.08 0.651 1.81 -0.941 0.784 0.23 0.638 0.39 0.0763 1.67 -0.619 0.727 0.395 0.404 0.539 0.118 2.14 0.756 0.699 0.279 0.554 2.13 0.562 8.98 PRS_PLINK_0.000199526231496888 TRUE 214.1 Lipoma of skin and subcutaneous tissue Both 19 75 2 neoplasms darkcyan 75, 19 19, 4 19, 4 18, 4 19, 7 -0.0984 0.334 0.768 0.115 0.906 0.475 1.75 -1.26 1.1 0.253 0.597 0.285 0.0245 2.01 0.0275 0.856 0.974 0.011 1.03 0.184 5.45 -0.816 1.16 0.483 0.316 0.442 0.0282 4.06 PRS_PLINK_0.000199526231496888 TRUE 215 Other benign neoplasm of connective and other soft tissue Both 63 367 2 neoplasms darkcyan 367, 63 92, 19 92, 18 91, 10 92, 15 -0.271 0.142 0.0565 1.248 0.763 0.574 1.01 -0.0125 0.376 0.973 0.012 0.988 0.471 2.06 -0.833 0.436 0.0558 1.253 0.435 0.175 1.01 -0.375 0.396 0.343 0.464 0.687 0.31 1.48 PRS_PLINK_0.000199526231496888 FALSE 216 Benign neoplasm of skin Both 179 268 2 neoplasms darkcyan 268, 179 66, 37 67, 37 67, 43 67, 62 0.161 0.104 0.122 0.914 1.17 0.961 1.44 -0.0532 0.315 0.866 0.063 0.948 0.517 1.73 0.18 0.303 0.553 0.257 1.2 0.669 2.15 0.423 0.294 0.15 0.823 1.53 0.869 2.7 PRS_PLINK_0.000199526231496888 FALSE 216.1 Screening for malignant neoplasms of the skin Both 4 15 2 neoplasms darkcyan 15, 4 4, 1 4, 2 3, 1 4, 0 0.0622 0.936 0.947 0.024 1.06 0.234 4.71 -0.754 3.55 0.832 0.08 0.47 0.000704 102 0.479 4.94 0.923 0.035 1.61 2.66 2.53 -1.09 11600000 1 0 0.336 0.000532 31.6 PRS_PLINK_0.000199526231496888 TRUE 217 Vascular hamartomas and non-neoplastic nevi Both 36 107 2 neoplasms darkcyan 107, 36 26, 9 27, 5 26, 8 27, 14 0.114 0.209 0.584 0.234 1.12 0.757 1.69 -0.813 0.691 0.239 0.621 0.444 0.111 1.55 -0.0327 0.596 0.956 0.019 0.968 0.31 3.02 0.613 0.608 0.314 0.503 1.85 0.6 6.1 PRS_PLINK_0.000199526231496888 TRUE 217.1 Nevus, non-neoplastic Both 33 98 2 neoplasms darkcyan 98, 33 24, 8 24, 6 24, 6 25, 13 0.18 0.224 0.422 0.375 1.2 0.787 1.86 -0.318 0.666 0.633 0.198 0.728 0.196 2.54 -0.215 0.681 0.752 0.124 0.807 0.212 3 0.757 0.653 0.246 0.608 2.13 0.65 7.69 PRS_PLINK_0.000199526231496888 TRUE 218 Benign neoplasm of uterus Female 150 159 2 neoplasms darkcyan 159, 150 40, 40 40, 35 39, 44 40, 30 -0.121 0.121 0.316 0.5 0.886 0.701 1.12 -0.232 0.341 0.497 0.304 0.793 0.411 1.52 -0.0109 0.33 0.974 0.012 0.989 0.525 1.86 -0.119 0.364 0.744 0.128 0.888 0.443 1.78 PRS_PLINK_0.000199526231496888 FALSE 218.1 Uterine leiomyoma Female 41 143 2 neoplasms darkcyan 143, 41 36, 13 36, 10 35, 10 36, 7 -0.307 0.194 0.113 0.947 0.736 0.5 1.07 -0.474 0.52 0.362 0.442 0.622 0.221 1.66 -0.583 0.524 0.266 0.575 0.558 0.194 1.49 -0.514 0.555 0.355 0.45 0.598 0.196 1.7 PRS_PLINK_0.000199526231496888 TRUE 218.2 Other benign neoplasm of uterus Female 135 158 2 neoplasms darkcyan 158, 135 40, 35 39, 32 39, 36 40, 31 -0.0965 0.125 0.441 0.356 0.908 0.713 1.15 -0.176 0.353 0.619 0.208 0.839 0.425 1.64 -0.0415 0.343 0.904 0.044 0.959 0.497 1.84 0.0749 0.373 0.841 0.075 1.08 0.528 2.21 PRS_PLINK_0.000199526231496888 FALSE 220 Benign neoplasm of ovary Female 22 97 2 neoplasms darkcyan 97, 22 25, 5 24, 7 24, 7 24, 3 -0.136 0.261 0.602 0.22 0.873 0.525 1.45 0.14 0.672 0.835 0.079 1.15 0.317 4.24 0.315 0.669 0.637 0.196 1.37 0.383 5.19 -0.677 0.862 0.433 0.364 0.508 0.0829 2.51 PRS_PLINK_0.000199526231496888 TRUE 221 Benign neoplasm of other female genital organs Female 63 147 2 neoplasms darkcyan 147, 63 37, 15 37, 13 36, 24 37, 11 -0.0327 0.163 0.84 0.076 0.968 0.706 1.33 -0.242 0.466 0.603 0.219 0.785 0.319 1.89 0.35 0.423 0.408 0.39 1.42 0.636 3.22 -0.515 0.525 0.326 0.486 0.598 0.21 1.61 PRS_PLINK_0.000199526231496888 FALSE 222 Benign neoplasm of male genital organs Male 3 34 2 neoplasms darkcyan 34, 3 9, 1 8, 1 8, 0 9, 1 0.392 0.555 0.48 0.319 1.48 0.507 5.31 1.21 1.95 0.536 0.271 3.34 0.00054 399000 -0.024 1.72 0.989 0.005 0.976 0.00828 449 0.85 1.58 0.591 0.228 2.34 0.039 568 PRS_PLINK_0.000199526231496888 TRUE 223 Benign neoplasm of kidney and other urinary organs Both 16 62 2 neoplasms darkcyan 62, 16 16, 4 15, 5 15, 4 16, 3 -0.137 0.34 0.688 0.163 0.872 0.441 1.67 -0.187 0.837 0.824 0.084 0.83 0.158 3.93 -0.388 0.945 0.682 0.166 0.679 0.096 3.93 -3.14 1.79 0.079 1.102 0.0432 6.43e-07 0.89 PRS_PLINK_0.000199526231496888 TRUE 224 Benign neoplasm of eye Both 12 32 2 neoplasms darkcyan 32, 12 8, 2 8, 0 8, 5 8, 5 0.687 0.442 0.12 0.921 1.99 0.886 5.43 -1.06 1.54 0.492 0.308 0.347 0.00487 3.82 -0.538 1.26 0.669 0.175 0.584 0.0297 5.54 0.915 1.2 0.444 0.353 2.5 0.324 28.8 PRS_PLINK_0.000199526231496888 TRUE 224.1 Benign neoplasm of eye, uveal Both 11 27 2 neoplasms darkcyan 27, 11 7, 2 7, 0 6, 3 7, 6 0.658 0.5 0.188 0.725 1.93 0.76 6 -0.727 1.65 0.659 0.181 0.483 0.00861 5.99 -0.913 1.49 0.539 0.268 0.401 0.0186 4.6 1.95 1.51 0.195 0.71 7.03 0.682 4280 PRS_PLINK_0.000199526231496888 TRUE 225 Benign neoplasm of brain and other parts of nervous system Both 11 93 2 neoplasms darkcyan 93, 11 24, 3 23, 2 23, 4 23, 2 -0.0493 0.325 0.879 0.056 0.952 0.5 1.8 0.491 1.24 0.692 0.16 1.63 0.14 23.7 0.267 0.943 0.777 0.109 1.31 0.197 9.46 -0.811 1.1 0.46 0.338 0.445 0.0338 3.57 PRS_PLINK_0.000199526231496888 TRUE 225.1 Benign neoplasm of brain, cranial nerves, meninges Both 9 69 2 neoplasms darkcyan 69, 9 18, 3 17, 1 17, 3 17, 2 0.0327 0.424 0.939 0.028 1.03 0.444 2.37 0.49 1.51 0.745 0.128 1.63 0.074 36.2 0.375 1.1 0.732 0.135 1.45 0.169 12.1 -0.899 1.26 0.477 0.321 0.407 0.00601 4.35 PRS_PLINK_0.000199526231496888 TRUE 225.2 Benign neoplasm of spinal cord, meninges Both 3 24 2 neoplasms darkcyan 24, 3 6, 1 6, 0 6, 1 6, 1 -0.563 0.712 0.429 0.368 0.569 0.0384 1.98 0.198 2.2 0.928 0.032 1.22 0.00277 647 0.328 2.52 0.896 0.047 1.39 1.92e-05 78.1 -0.902 1.67 0.59 0.229 0.406 0.00295 6.01 PRS_PLINK_0.000199526231496888 TRUE 226 Benign neoplasm of thyroid glands Both 22 140 2 neoplasms darkcyan 140, 22 35, 5 35, 8 35, 1 35, 8 -0.213 0.248 0.39 0.409 0.808 0.492 1.32 0.645 0.713 0.366 0.437 1.91 0.482 8.39 -1.36 0.919 0.139 0.856 0.257 0.025 1.47 0.275 0.649 0.672 0.172 1.32 0.377 4.95 PRS_PLINK_0.000199526231496888 TRUE 227 Benign neoplasm of other endocrine glands and related structures Both 15 139 2 neoplasms darkcyan 139, 15 35, 4 35, 4 34, 2 35, 5 0.00504 0.316 0.987 0.006 1.01 0.528 1.9 0.27 0.82 0.742 0.13 1.31 0.258 7.7 -0.591 1.02 0.564 0.249 0.554 0.0454 4.92 0.163 0.805 0.839 0.076 1.18 0.23 6.23 PRS_PLINK_0.000199526231496888 TRUE 227.1 Benign neoplasm of adrenal gland Both 4 40 2 neoplasms darkcyan 40, 4 10, 2 10, 0 10, 1 10, 1 -0.055 0.647 0.932 0.03 0.946 0.213 3.48 -0.526 1.27 0.678 0.169 0.591 0.01 29 -1.09 1.42 0.441 0.356 0.335 3.82e-05 41.8 -0.292 1.39 0.833 0.079 0.747 0.00736 13.1 PRS_PLINK_0.000199526231496888 TRUE 227.2 Benign neoplasm of parathyroid gland Both 8 57 2 neoplasms darkcyan 57, 8 15, 2 14, 3 14, 1 14, 2 -0.113 0.47 0.81 0.092 0.893 0.318 2.5 -1.24 1.75 0.481 0.318 0.29 3.65e-11 7.79 -0.263 1.4 0.851 0.07 0.769 0.000141 69.3 -0.339 1.31 0.796 0.099 0.712 0.0328 8.41 PRS_PLINK_0.000199526231496888 TRUE 227.3 Benign neoplasm of pituitary gland and craniopharyngeal duct (pouch) Both 4 35 2 neoplasms darkcyan 35, 4 9, 0 9, 1 8, 0 9, 3 1.36 0.935 0.145 0.838 3.91 0.666 54.6 0.69 1.49 0.644 0.191 1.99 0.144 1490 0.123 1.81 0.945 0.024 1.13 0.0122 57.7 PRS_PLINK_0.000199526231496888 TRUE 228 Hemangioma and lymphangioma, any site Both 44 160 2 neoplasms darkcyan 160, 44 39, 6 40, 9 40, 16 40, 13 0.331 0.189 0.0807 1.093 1.39 0.969 2.04 0.434 0.556 0.435 0.362 1.54 0.527 4.87 0.875 0.534 0.101 0.994 2.4 0.882 7.3 0.743 0.541 0.17 0.77 2.1 0.758 6.31 PRS_PLINK_0.000199526231496888 TRUE 228.1 Hemangioma of skin and subcutaneous tissue Both 27 89 2 neoplasms darkcyan 89, 27 23, 6 22, 3 22, 10 22, 8 0.343 0.262 0.191 0.719 1.41 0.864 2.37 -0.445 0.778 0.567 0.247 0.641 0.114 2.84 0.451 0.629 0.473 0.325 1.57 0.489 5.4 0.678 0.713 0.342 0.466 1.97 0.53 8.62 PRS_PLINK_0.000199526231496888 TRUE 229 Benign neoplasm of unspecified sites Both 50 379 2 neoplasms darkcyan 379, 50 94, 16 95, 11 94, 10 95, 13 -0.182 0.154 0.237 0.625 0.833 0.613 1.13 -0.495 0.423 0.242 0.616 0.61 0.257 1.4 -0.593 0.428 0.165 0.781 0.552 0.23 1.27 -0.452 0.424 0.286 0.543 0.636 0.271 1.45 PRS_PLINK_0.000199526231496888 TRUE 229.1 Benign neoplasm of lymph nodes Both 23 358 2 neoplasms darkcyan 358, 23 89, 7 89, 8 89, 4 90, 4 -0.387 0.206 0.0606 1.217 0.679 0.447 1.03 0.11 0.535 0.837 0.077 1.12 0.373 3.45 -0.599 0.599 0.317 0.499 0.549 0.146 1.89 -0.875 0.63 0.165 0.782 0.417 0.104 1.46 PRS_PLINK_0.000199526231496888 TRUE 240 Simple and unspecified goiter Both 24 124 3 endocrine/metabolic brown 124, 24 30, 8 31, 5 31, 4 31, 7 -0.0617 0.219 0.778 0.109 0.94 0.608 1.44 -0.478 0.666 0.473 0.325 0.62 0.159 2.24 -1.04 0.755 0.166 0.779 0.352 0.061 1.44 -0.386 0.607 0.525 0.28 0.68 0.204 2.12 PRS_PLINK_0.000199526231496888 TRUE 241 Nontoxic nodular goiter Both 46 260 3 endocrine/metabolic brown 260, 46 64, 12 65, 10 65, 8 65, 16 -0.0154 0.169 0.927 0.033 0.985 0.707 1.38 -0.287 0.489 0.557 0.254 0.751 0.281 1.97 -0.487 0.516 0.345 0.462 0.615 0.212 1.69 0.182 0.444 0.682 0.166 1.2 0.505 2.9 PRS_PLINK_0.000199526231496888 TRUE 241.1 Nontoxic uninodular goiter Both 39 226 3 endocrine/metabolic brown 226, 39 56, 9 56, 9 56, 7 57, 14 -0.0286 0.181 0.874 0.058 0.972 0.682 1.39 -0.0981 0.559 0.861 0.065 0.907 0.298 2.78 -0.39 0.568 0.492 0.308 0.677 0.211 2.05 0.275 0.489 0.574 0.241 1.32 0.508 3.51 PRS_PLINK_0.000199526231496888 TRUE 241.2 Nontoxic multinodular goiter Both 21 127 3 endocrine/metabolic brown 127, 21 31, 7 32, 5 31, 6 32, 3 -0.454 0.234 0.0524 1.281 0.635 0.392 0.996 -0.414 0.733 0.572 0.243 0.661 0.147 2.85 -0.463 0.656 0.481 0.318 0.63 0.162 2.23 -0.863 0.691 0.212 0.674 0.422 0.0968 1.56 PRS_PLINK_0.000199526231496888 TRUE 242 Thyrotoxicosis with or without goiter Both 31 154 3 endocrine/metabolic brown 154, 31 39, 7 38, 6 38, 7 39, 11 0.297 0.23 0.197 0.706 1.35 0.86 2.15 -0.172 0.602 0.775 0.111 0.842 0.252 2.74 -0.0243 0.575 0.966 0.015 0.976 0.311 3.08 0.395 0.546 0.47 0.328 1.48 0.519 4.44 PRS_PLINK_0.000199526231496888 TRUE 242.1 Graves' disease Both 10 71 3 endocrine/metabolic brown 71, 10 18, 3 18, 2 17, 2 18, 3 0.178 0.399 0.656 0.183 1.19 0.504 2.77 -1.68 1.36 0.215 0.668 0.186 0.0041 2.04 -0.0486 0.944 0.959 0.018 0.953 0.125 6.45 -0.734 1.12 0.513 0.29 0.48 0.0209 4.73 PRS_PLINK_0.000199526231496888 TRUE 242.2 Toxic multinodular goiter Both 1 13 3 endocrine/metabolic brown 13, 1 4, 0 3, 1 3, 0 3, 0 -0.472 0.968 0.626 0.203 0.624 0.035 4.24 0.291 9.69 0.976 0.011 1.34 1.57 1.78 PRS_PLINK_0.000199526231496888 TRUE 242.3 Exophthalmos Both 4 29 3 endocrine/metabolic brown 29, 4 8, 1 7, 1 7, 1 7, 1 0.00501 0.596 0.993 0.003 1.01 0.288 4.41 1.1 2.19 0.616 0.21 3 0.0882 1.03e+09 -0.056 1.67 0.973 0.012 0.946 0.0236 48.1 -0.404 1.65 0.807 0.093 0.668 0.000564 45.8 PRS_PLINK_0.000199526231496888 TRUE 242.31 Thyrotoxic exophthalmos Both 3 15 3 endocrine/metabolic brown 15, 3 4, 1 4, 1 3, 0 4, 1 -0.215 0.859 0.803 0.095 0.807 0.103 5.23 4.14 4.27 0.333 0.478 62.7 0.163 1.77e+08 -0.351 5.34 0.948 0.023 0.704 5.67e-07 4860 -0.0661 2.58 0.98 0.009 0.936 0.00318 61 PRS_PLINK_0.000199526231496888 TRUE 244 Hypothyroidism Both 96 305 3 endocrine/metabolic brown 305, 96 76, 25 76, 23 76, 26 76, 22 -0.0507 0.124 0.683 0.166 0.951 0.746 1.21 -0.117 0.346 0.735 0.134 0.889 0.452 1.74 0.0113 0.344 0.974 0.012 1.01 0.519 1.97 -0.209 0.361 0.564 0.249 0.812 0.401 1.62 PRS_PLINK_0.000199526231496888 FALSE 244.1 Secondary hypothyroidism Both 20 184 3 endocrine/metabolic brown 184, 20 45, 4 46, 6 46, 4 46, 6 -0.0945 0.237 0.69 0.161 0.91 0.563 1.48 0.272 0.635 0.668 0.175 1.31 0.369 5.02 -0.0892 0.684 0.896 0.048 0.915 0.216 3.79 -0.134 0.704 0.85 0.071 0.875 0.198 3.75 PRS_PLINK_0.000199526231496888 TRUE 244.2 Acquired hypothyroidism Both 34 149 3 endocrine/metabolic brown 149, 34 38, 10 37, 10 37, 7 37, 7 -0.106 0.197 0.59 0.229 0.899 0.607 1.32 -0.0572 0.529 0.914 0.039 0.944 0.337 2.64 -0.33 0.567 0.56 0.252 0.719 0.23 2.17 -0.154 0.572 0.787 0.104 0.857 0.275 2.58 PRS_PLINK_0.000199526231496888 TRUE 244.4 Hypothyroidism NOS Both 93 304 3 endocrine/metabolic brown 304, 93 75, 25 76, 21 76, 26 76, 21 -0.0522 0.125 0.676 0.17 0.949 0.744 1.21 -0.202 0.35 0.564 0.249 0.817 0.411 1.61 -0.00197 0.343 0.995 0.002 0.998 0.513 1.94 -0.286 0.367 0.436 0.361 0.751 0.367 1.52 PRS_PLINK_0.000199526231496888 FALSE 245 Thyroiditis Both 16 107 3 endocrine/metabolic brown 107, 16 27, 5 27, 2 26, 4 27, 5 -0.0424 0.266 0.873 0.059 0.958 0.554 1.63 -0.933 0.956 0.329 0.483 0.393 0.0445 2.38 -0.324 0.729 0.657 0.182 0.724 0.158 3.02 0.152 0.679 0.823 0.085 1.16 0.304 4.54 PRS_PLINK_0.000199526231496888 TRUE 245.2 Chronic thyroiditis Both 13 94 3 endocrine/metabolic brown 94, 13 24, 5 23, 2 23, 3 24, 3 -0.231 0.303 0.446 0.351 0.794 0.41 1.44 -0.768 0.974 0.431 0.366 0.464 0.0523 2.79 -0.549 0.785 0.484 0.315 0.578 0.108 2.61 -0.356 0.822 0.665 0.177 0.7 0.123 3.42 PRS_PLINK_0.000199526231496888 TRUE 245.21 Chronic lymphocytic thyroiditis Both 13 95 3 endocrine/metabolic brown 95, 13 24, 5 24, 2 23, 3 24, 3 -0.281 0.303 0.353 0.452 0.755 0.39 1.37 -1.11 0.973 0.252 0.598 0.328 0.0332 1.94 -0.591 0.773 0.444 0.353 0.554 0.106 2.43 -0.389 0.844 0.645 0.191 0.678 0.111 3.42 PRS_PLINK_0.000199526231496888 TRUE 246 Other disorders of thyroid Both 69 298 3 endocrine/metabolic brown 298, 69 74, 12 74, 22 74, 17 75, 18 0.0633 0.143 0.658 0.182 1.07 0.806 1.41 0.381 0.409 0.352 0.453 1.46 0.663 3.31 0.278 0.425 0.512 0.29 1.32 0.579 3.08 0.298 0.417 0.475 0.323 1.35 0.601 3.09 PRS_PLINK_0.000199526231496888 FALSE 246.2 Thyroid cyst Both 5 10 3 endocrine/metabolic brown 10, 5 3, 4 2, 0 2, 1 3, 0 -0.43 0.839 0.608 0.216 0.651 0.143 2.46 -0.472 9.1 0.959 0.018 0.624 0.604 0.645 -0.314 2.09 0.88 0.055 0.731 0.713 0.75 -1.6 80.3 0.984 0.007 0.201 5.43e-05 721 PRS_PLINK_0.000199526231496888 TRUE 246.7 Abnormal results of function study of thyroid Both 16 100 3 endocrine/metabolic brown 100, 16 24, 5 25, 5 25, 2 25, 4 -0.083 0.279 0.766 0.116 0.92 0.529 1.62 0.0717 0.727 0.921 0.036 1.07 0.251 4.74 -0.854 0.809 0.291 0.536 0.426 0.068 2.02 -0.203 0.731 0.781 0.107 0.816 0.19 3.34 PRS_PLINK_0.000199526231496888 TRUE 249 Secondary diabetes mellitus Both 7 44 3 endocrine/metabolic brown 44, 7 11, 3 11, 2 11, 1 11, 1 -0.331 0.408 0.418 0.379 0.718 0.329 1.54 0.464 1.17 0.693 0.16 1.59 0.194 44.4 -0.00807 1.41 0.995 0.002 0.992 0.0703 15.5 -1.1 1.4 0.431 0.366 0.332 5.92e-05 15.7 PRS_PLINK_0.000199526231496888 TRUE 250 Diabetes mellitus Both 180 272 3 endocrine/metabolic brown 272, 180 68, 42 68, 45 68, 47 68, 45 -0.024 0.102 0.815 0.089 0.976 0.801 1.19 0.087 0.292 0.766 0.116 1.09 0.621 1.92 0.0346 0.288 0.904 0.044 1.04 0.595 1.8 -0.0925 0.304 0.761 0.119 0.912 0.506 1.63 PRS_PLINK_0.000199526231496888 FALSE 250.1 Type 1 diabetes Both 8 67 3 endocrine/metabolic brown 67, 8 17, 1 17, 3 16, 0 17, 4 0.688 0.393 0.0794 1.1 1.99 0.945 4.73 1.09 1.28 0.394 0.405 2.98 0.241 87.5 0.642 1.52 0.673 0.172 1.9 0.0116 9000 1.4 1.09 0.198 0.704 4.07 0.588 107 PRS_PLINK_0.000199526231496888 TRUE 250.11 Type 1 diabetes with ketoacidosis Both 1 15 3 endocrine/metabolic brown 15, 1 4, 0 4, 0 3, 0 4, 1 0.415 1.11 0.708 0.15 1.51 0.205 42.9 1.27 33.6 0.97 0.013 3.56 3 196000 PRS_PLINK_0.000199526231496888 TRUE 250.12 Type 1 diabetes with renal manifestations Both 3 13 3 endocrine/metabolic brown 13, 3 4, 0 3, 0 3, 2 3, 1 1.7 1.53 0.267 0.574 5.46 0.575 890 0.651 24.3 0.979 0.009 1.92 2.15 3080 0.401 23700000 1 0 1.49 0.0701 21.4 PRS_PLINK_0.000199526231496888 TRUE 250.13 Type 1 diabetes with ophthalmic manifestations Both 2 17 3 endocrine/metabolic brown 17, 2 5, 0 4, 0 4, 0 4, 2 0.934 1.11 0.402 0.396 2.54 0.109 60.2 2.79 12.3 0.821 0.086 16.3 1.33e-06 5.15e+08 PRS_PLINK_0.000199526231496888 TRUE 250.14 Type 1 diabetes with neurological manifestations Both 2 13 3 endocrine/metabolic brown 13, 2 4, 0 3, 0 3, 0 3, 2 0.856 1.29 0.506 0.296 2.35 0.25 41.6 3.15 149 0.983 0.007 23.4 0.0217 190 PRS_PLINK_0.000199526231496888 TRUE 250.15 Diabetes type 1 with peripheral circulatory disorders Both 0 5 3 endocrine/metabolic brown 5, 0 2 1 1 1 PRS_PLINK_0.000199526231496888 TRUE 250.2 Type 2 diabetes Both 65 255 3 endocrine/metabolic brown 255, 65 64, 18 64, 16 63, 13 64, 18 -0.0329 0.153 0.83 0.081 0.968 0.716 1.3 -0.0802 0.419 0.848 0.071 0.923 0.403 2.1 -0.349 0.431 0.418 0.379 0.706 0.3 1.62 0.00513 0.426 0.99 0.004 1.01 0.436 2.31 PRS_PLINK_0.000199526231496888 FALSE 250.21 Type 2 diabetes with ketoacidosis Both 1 10 3 endocrine/metabolic brown 10, 1 3, 0 2, 0 2, 0 3, 1 1.61 6.33 0.799 0.097 5 0.00599 14000 0.156 867 1 0 1.17 0.689 3.8 PRS_PLINK_0.000199526231496888 TRUE 250.22 Type 2 diabetes with renal manifestations Both 8 62 3 endocrine/metabolic brown 62, 8 16, 3 15, 1 15, 3 16, 1 -0.583 0.486 0.23 0.638 0.558 0.18 1.43 0.0935 1.39 0.946 0.024 1.1 0.00392 122 -0.0437 1.16 0.97 0.013 0.957 0.0964 16 -0.667 1.13 0.553 0.257 0.513 0.0169 7.14 PRS_PLINK_0.000199526231496888 TRUE 250.23 Type 2 diabetes with ophthalmic manifestations Both 5 49 3 endocrine/metabolic brown 49, 5 13, 0 12, 1 12, 0 12, 4 0.934 0.497 0.0601 1.221 2.54 1.02 8.58 0.905 1.57 0.563 0.249 2.47 0.00567 2610 2.21 1.52 0.145 0.839 9.12 0.698 2390 PRS_PLINK_0.000199526231496888 TRUE 250.24 Type 2 diabetes with neurological manifestations Both 8 78 3 endocrine/metabolic brown 78, 8 20, 3 19, 1 19, 1 20, 3 0.281 0.39 0.471 0.327 1.32 0.597 2.96 0.92 1.27 0.469 0.329 2.51 0.167 177 -0.289 1.15 0.801 0.096 0.749 0.0646 13.3 0.702 1.16 0.545 0.263 2.02 0.207 62.5 PRS_PLINK_0.000199526231496888 TRUE 250.25 Diabetes type 2 with peripheral circulatory disorders Both 4 27 3 endocrine/metabolic brown 27, 4 7, 0 7, 0 6, 0 7, 4 1.52 0.841 0.0704 1.153 4.58 1.05 191 1.31 2.63 0.618 0.209 3.7 0.0161 827000 PRS_PLINK_0.000199526231496888 TRUE 250.3 Insulin pump user Both 24 128 3 endocrine/metabolic brown 128, 24 32, 4 32, 2 32, 6 32, 12 0.537 0.253 0.0336 1.473 1.71 1.06 2.86 -0.727 1.01 0.473 0.325 0.483 0.0332 4.01 0.186 0.724 0.797 0.098 1.2 0.276 5.25 0.768 0.696 0.27 0.569 2.16 0.564 9.04 PRS_PLINK_0.000199526231496888 TRUE 250.4 Abnormal glucose Both 160 268 3 endocrine/metabolic brown 268, 160 67, 36 67, 42 67, 42 67, 39 -0.0235 0.107 0.826 0.083 0.977 0.794 1.2 0.171 0.307 0.578 0.238 1.19 0.657 2.15 0.0696 0.304 0.819 0.087 1.07 0.598 1.93 -0.0804 0.324 0.804 0.095 0.923 0.493 1.72 PRS_PLINK_0.000199526231496888 FALSE 250.41 Impaired fasting glucose Both 70 108 3 endocrine/metabolic brown 108, 70 27, 21 27, 15 27, 15 27, 19 -0.069 0.158 0.662 0.179 0.933 0.69 1.26 -0.535 0.493 0.277 0.557 0.585 0.226 1.45 -0.773 0.503 0.125 0.905 0.462 0.171 1.16 -0.205 0.457 0.654 0.184 0.815 0.342 1.91 PRS_PLINK_0.000199526231496888 FALSE 250.42 Other abnormal glucose Both 121 255 3 endocrine/metabolic brown 255, 121 64, 22 64, 35 63, 36 64, 27 0.0314 0.123 0.798 0.098 1.03 0.814 1.31 0.477 0.346 0.168 0.774 1.61 0.831 3.18 0.421 0.343 0.22 0.657 1.52 0.792 2.97 0.0995 0.38 0.793 0.101 1.1 0.531 2.3 PRS_PLINK_0.000199526231496888 FALSE 250.5 Glycosuria or Acetonuria Both 5 21 3 endocrine/metabolic brown 21, 5 6, 3 5, 0 5, 1 5, 1 -0.192 0.808 0.812 0.091 0.825 0.159 3.84 -1.54 2.05 0.452 0.345 0.214 0.00182 5.69 -0.0226 1.85 0.99 0.004 0.978 0.00309 19.9 3.25 5.78 0.574 0.241 25.8 0.0074 32.6 PRS_PLINK_0.000199526231496888 TRUE 250.6 Polyneuropathy in diabetes Both 5 65 3 endocrine/metabolic brown 65, 5 17, 2 16, 0 16, 0 16, 3 0.379 0.426 0.374 0.427 1.46 0.609 3.76 0.0473 1.32 0.971 0.013 1.05 0.000721 89.6 -0.479 1.36 0.725 0.14 0.619 0.0102 74 0.991 1.2 0.409 0.388 2.69 0.289 74.9 PRS_PLINK_0.000199526231496888 TRUE 250.7 Diabetic retinopathy Both 5 65 3 endocrine/metabolic brown 65, 5 17, 0 16, 1 16, 0 16, 4 1.28 0.554 0.0205 1.689 3.61 1.32 24.4 0.175 1.34 0.896 0.047 1.19 0.0268 45.9 3.27 1.76 0.0624 1.205 26.4 1.53 2270000 PRS_PLINK_0.000199526231496888 TRUE 251 Other disorders of pancreatic internal secretion Both 15 72 3 endocrine/metabolic brown 72, 15 18, 3 18, 4 18, 5 18, 3 0.257 0.367 0.484 0.315 1.29 0.636 2.71 1.94 1.58 0.219 0.659 6.96 0.494 14900000 0.835 0.978 0.393 0.406 2.31 0.356 22.6 2.78 1.8 0.122 0.913 16.1 0.87 369000 PRS_PLINK_0.000199526231496888 TRUE 251.1 Hypoglycemia Both 22 58 3 endocrine/metabolic brown 58, 22 15, 4 14, 7 14, 3 15, 8 0.343 0.326 0.292 0.534 1.41 0.767 2.69 1.19 0.914 0.193 0.714 3.28 0.68 20.7 -0.0273 0.924 0.976 0.01 0.973 0.163 5.33 1.31 1.02 0.198 0.704 3.72 0.611 39 PRS_PLINK_0.000199526231496888 TRUE 252 Disorders of parathyroid gland Both 42 153 3 endocrine/metabolic brown 153, 42 39, 15 38, 9 38, 9 38, 9 -0.124 0.189 0.512 0.291 0.883 0.607 1.28 -0.421 0.51 0.408 0.389 0.656 0.241 1.73 -0.251 0.538 0.641 0.193 0.778 0.266 2.22 -0.0912 0.542 0.866 0.062 0.913 0.315 2.65 PRS_PLINK_0.000199526231496888 TRUE 252.1 Hyperparathyroidism Both 38 127 3 endocrine/metabolic brown 127, 38 32, 12 32, 10 31, 9 32, 7 -0.0992 0.196 0.613 0.212 0.906 0.615 1.33 -0.0911 0.529 0.863 0.064 0.913 0.329 2.52 -0.0218 0.584 0.97 0.013 0.978 0.31 3.1 0.0912 0.638 0.886 0.052 1.1 0.313 3.98 PRS_PLINK_0.000199526231496888 TRUE 252.2 Hypoparathyroidism Both 10 41 3 endocrine/metabolic brown 41, 10 11, 4 10, 1 10, 2 10, 3 -0.0735 0.394 0.852 0.07 0.929 0.444 2 -0.491 1.1 0.656 0.183 0.612 0.0685 4.47 -1.07 1.47 0.468 0.33 0.344 0.00318 5.72 0.432 1.19 0.717 0.145 1.54 0.186 14.8 PRS_PLINK_0.000199526231496888 TRUE 253 Disorders of the pituitary gland and its hypothalamic control Both 16 72 3 endocrine/metabolic brown 72, 16 17, 5 18, 3 18, 5 18, 3 -0.145 0.286 0.612 0.213 0.865 0.487 1.51 -0.512 0.845 0.544 0.264 0.599 0.108 3.01 -0.0143 0.774 0.985 0.006 0.986 0.232 4.27 -0.49 0.867 0.572 0.243 0.612 0.105 3.08 PRS_PLINK_0.000199526231496888 TRUE 253.1 Pituitary hyperfunction Both 10 27 3 endocrine/metabolic brown 27, 10 7, 3 7, 2 6, 4 7, 1 -0.19 0.416 0.647 0.189 0.827 0.314 1.88 0.59 1.69 0.727 0.138 1.8 0.00607 2.08 0.753 1.35 0.577 0.239 2.12 0.218 94.5 -0.908 1.6 0.571 0.244 0.403 0.0104 5.52 PRS_PLINK_0.000199526231496888 TRUE 253.11 Acromegaly and gigantism Both 1 2 3 endocrine/metabolic brown 2, 1 1, 0 1, 1 1, 0 1, 1 0.00361 262 1 0 1 0.732 1.23 -0.00148 52.6 1 0 0.999 0.946 1.06 PRS_PLINK_0.000199526231496888 TRUE 253.2 Pituitary hypofunction Both 3 12 3 endocrine/metabolic brown 12, 3 3, 1 3, 0 3, 2 3, 0 0.927 1.48 0.532 0.274 2.53 0.0986 4750 1.39 13700000 1 0 4.02 0.00107 56200 1.86 85.8 0.983 0.008 6.44 0.231 19.6 0.00419 925 1 0 1 0.797 1.57 PRS_PLINK_0.000199526231496888 TRUE 253.3 Diabetes insipidus Both 0 5 3 endocrine/metabolic brown 5, 0 2 1 1 1 PRS_PLINK_0.000199526231496888 TRUE 253.4 Anterior pituitary disorders Both 4 4 3 endocrine/metabolic brown 4, 4 1, 1 1, 1 1, 1 1, 1 -0.112 6270000 1 0 0.894 0.0536 16.1 -5.29 38300 1 0 0.00507 5.1e-10 267000 -0.628 50100 1 0 0.534 0.0967 7.8 -0.0111 814 1 0 0.989 0.617 1.51 PRS_PLINK_0.000199526231496888 TRUE 253.7 Other disorders of neurohypophysis Both 2 11 3 endocrine/metabolic brown 11, 2 3, 1 3, 0 2, 1 3, 0 0.0932 1.51 0.951 0.022 1.1 0.727 1.18 -0.167 97900000 1 0 0.846 1.5e-06 569000 1.09 31700 1 0 2.99 0.017 7.32 -0.0405 3860 1 0 0.96 0.255 1.89 PRS_PLINK_0.000199526231496888 TRUE 255 Disorders of adrenal glands Both 21 110 3 endocrine/metabolic brown 110, 21 28, 6 27, 3 27, 5 28, 7 0.0758 0.297 0.799 0.098 1.08 0.598 1.95 -0.669 0.805 0.406 0.392 0.512 0.0853 2.38 0.312 0.783 0.69 0.161 1.37 0.289 6.82 0.747 0.862 0.386 0.413 2.11 0.414 13 PRS_PLINK_0.000199526231496888 TRUE 255.1 Adrenal hyperfunction Both 8 38 3 endocrine/metabolic brown 38, 8 10, 2 9, 2 9, 1 10, 3 0.279 0.461 0.544 0.264 1.32 0.544 3.23 2.7 2.66 0.31 0.509 14.9 0.128 57200 -0.44 1.36 0.747 0.127 0.644 0.0437 7.48 0.852 1.57 0.587 0.232 2.34 0.0914 885 PRS_PLINK_0.000199526231496888 TRUE 255.11 Cushing's syndrome Both 5 21 3 endocrine/metabolic brown 21, 5 6, 0 5, 1 5, 2 5, 2 0.722 0.882 0.413 0.384 2.06 0.255 16.2 -0.185 2.73 0.946 0.024 0.831 0.0108 173 1.78 2.16 0.411 0.386 5.91 0.235 1410 -0.0642 2.34 0.978 0.01 0.938 0.00325 31.7 PRS_PLINK_0.000199526231496888 TRUE 255.12 Hyperaldosteronism Both 2 13 3 endocrine/metabolic brown 13, 2 4, 2 3, 0 3, 0 3, 0 -0.751 0.904 0.406 0.392 0.472 0.0345 2.1 -1.99 45 0.965 0.016 0.136 0.00247 7.21 -3.17 12.7 0.802 0.096 0.0418 0.0353 0.0483 -0.771 1680000 1 0 0.463 0.193 0.717 PRS_PLINK_0.000199526231496888 TRUE 255.2 Adrenal hypofunction Both 12 45 3 endocrine/metabolic brown 45, 12 12, 3 11, 4 11, 0 11, 5 0.0519 0.454 0.909 0.041 1.05 0.432 2.69 0.629 1.01 0.532 0.274 1.88 0.334 13 -0.578 1.66 0.729 0.138 0.561 0.00304 62.8 0.201 1.33 0.88 0.055 1.22 0.0483 37.5 PRS_PLINK_0.000199526231496888 TRUE 255.21 Glucocorticoid deficiency Both 11 41 3 endocrine/metabolic brown 41, 11 11, 4 10, 3 10, 0 10, 4 -0.57 0.525 0.277 0.557 0.565 0.187 1.51 0.287 1.02 0.779 0.109 1.33 0.211 9.61 -1.57 2 0.432 0.365 0.207 0.000216 24.1 -1.77 1.5 0.237 0.626 0.17 4.12e-06 2.37 PRS_PLINK_0.000199526231496888 TRUE 256 Ovarian dysfunction Female 86 201 3 endocrine/metabolic brown 201, 86 50, 18 50, 26 50, 17 50, 25 -0.0845 0.135 0.531 0.275 0.919 0.708 1.19 0.375 0.384 0.328 0.484 1.46 0.701 3.07 -0.159 0.4 0.692 0.16 0.853 0.394 1.83 0.19 0.407 0.642 0.193 1.21 0.555 2.65 PRS_PLINK_0.000199526231496888 FALSE 256.4 Polycystic ovaries Female 70 159 3 endocrine/metabolic brown 159, 70 39, 15 40, 23 39, 10 40, 22 -0.0669 0.151 0.659 0.181 0.935 0.699 1.25 0.385 0.43 0.371 0.431 1.47 0.651 3.39 -0.494 0.485 0.309 0.511 0.61 0.237 1.51 0.211 0.458 0.645 0.191 1.24 0.516 2.98 PRS_PLINK_0.000199526231496888 FALSE 257 Testicular dysfunction Male 8 24 3 endocrine/metabolic brown 24, 8 6, 1 6, 2 6, 1 6, 4 0.768 0.626 0.22 0.658 2.16 0.743 8.77 1.02 2.5 0.682 0.166 2.78 0.029 12900 -1.09 2.85 0.702 0.154 0.336 1.49e-07 1220 2.43 2.29 0.289 0.539 11.3 0.207 4.49e+16 PRS_PLINK_0.000199526231496888 TRUE 257.1 Testicular hypofunction Male 8 24 3 endocrine/metabolic brown 24, 8 6, 1 6, 2 6, 1 6, 4 0.768 0.626 0.22 0.658 2.16 0.743 8.77 1.02 2.5 0.682 0.166 2.78 0.029 12900 -1.09 2.85 0.702 0.154 0.336 1.49e-07 1220 2.43 2.29 0.289 0.539 11.3 0.207 4.49e+16 PRS_PLINK_0.000199526231496888 TRUE 258 Iatrogenic endocrine disorders Both 0 4 3 endocrine/metabolic brown 4, 0 1 1 1 1 PRS_PLINK_0.000199526231496888 TRUE 258.1 Postablative ovarian failure Female 3 16 3 endocrine/metabolic brown 16, 3 4, 2 4, 0 4, 1 4, 0 0.277 1.32 0.834 0.079 1.32 0.0123 57.3 -0.555 3.24 0.864 0.064 0.574 0.00183 218 -1.21 3.92 0.758 0.12 0.298 6.29e-05 210 -0.386 3.92 0.922 0.035 0.68 0.000588 127000 PRS_PLINK_0.000199526231496888 TRUE 259 Other endocrine disorders Both 33 88 3 endocrine/metabolic brown 88, 33 21, 5 22, 10 22, 8 22, 10 0.12 0.21 0.567 0.246 1.13 0.761 1.7 0.348 0.63 0.581 0.236 1.42 0.435 4.82 0.297 0.633 0.639 0.194 1.35 0.416 4.62 0.684 0.716 0.339 0.469 1.98 0.531 8.18 PRS_PLINK_0.000199526231496888 TRUE 260 Protein-calorie malnutrition Both 20 137 3 endocrine/metabolic brown 137, 20 35, 9 34, 6 34, 2 34, 3 -0.283 0.287 0.324 0.489 0.754 0.421 1.34 -0.217 0.694 0.754 0.123 0.805 0.199 3.13 -1.8 0.854 0.0354 1.451 0.166 0.0223 0.794 -0.929 0.765 0.224 0.649 0.395 0.343 0.488 PRS_PLINK_0.000199526231496888 TRUE 260.1 Cachexia Both 1 10 3 endocrine/metabolic brown 10, 1 3, 0 2, 0 2, 1 3, 0 -0.0562 3.31 0.986 0.006 0.945 0.0142 442 0.000114 14.4 1 0 1 0.807 1.21 PRS_PLINK_0.000199526231496888 TRUE 260.2 severe protein-calorie malnutrition Both 10 77 3 endocrine/metabolic brown 77, 10 20, 4 19, 2 19, 3 19, 1 -0.59 0.463 0.202 0.694 0.554 0.208 1.4 -0.347 1.15 0.764 0.117 0.707 0.0139 7.61 -0.142 0.976 0.884 0.053 0.868 0.114 6.28 -0.425 1.16 0.715 0.146 0.653 0.0473 7.87 PRS_PLINK_0.000199526231496888 TRUE 260.22 Nutritional marasmus Both 3 36 3 endocrine/metabolic brown 36, 3 9, 0 9, 1 9, 2 9, 0 0.102 0.671 0.879 0.056 1.11 0.307 5.79 1.14 1.51 0.449 0.347 3.12 0.256 975 0.639 1.5 0.67 0.174 1.89 0.116 66.3 PRS_PLINK_0.000199526231496888 TRUE 260.3 Adult failure to thrive Both 2 26 3 endocrine/metabolic brown 26, 2 7, 1 6, 0 6, 0 7, 1 0.501 0.739 0.498 0.303 1.65 0.337 32.9 -1 2.2 0.649 0.188 0.367 0.00445 42.8 -0.117 1.6 0.942 0.026 0.89 0.0146 29.5 0.339 1.66 0.839 0.076 1.4 0.0667 7460 PRS_PLINK_0.000199526231496888 TRUE 260.6 Anorexia Both 2 56 3 endocrine/metabolic brown 56, 2 14, 0 14, 0 14, 1 14, 1 0.287 0.693 0.678 0.169 1.33 0.257 9.38 0.248 1.35 0.854 0.068 1.28 0.00291 68.4 0.171 1.47 0.907 0.042 1.19 0.0099 216 PRS_PLINK_0.000199526231496888 TRUE 260.7 Polyphagia Both 1 9 3 endocrine/metabolic brown 9, 1 3, 0 2, 1 2, 0 2, 0 0.36 2990000 1 0 1.43 0.228 6.76 -0.0249 664 1 0 0.975 0.617 1.49 PRS_PLINK_0.000199526231496888 TRUE 261 Vitamin deficiency Both 193 240 3 endocrine/metabolic brown 240, 193 60, 64 60, 40 60, 35 60, 53 -0.0421 0.102 0.68 0.168 0.959 0.787 1.17 -0.347 0.283 0.22 0.657 0.707 0.41 1.22 -0.499 0.291 0.0861 1.065 0.607 0.346 1.06 -0.137 0.277 0.621 0.207 0.872 0.511 1.49 PRS_PLINK_0.000199526231496888 FALSE 261.1 Vitamin A deficiency Both 2 5 3 endocrine/metabolic brown 5, 2 2, 1 1, 0 1, 0 1, 1 -0.462 89.3 0.996 0.002 0.63 0.152 0.373 0.00737 221 1 0 1.01 0.917 1.12 -0.388 20500 1 0 0.679 0.00852 3.89 0.734 4500 1 0 2.08 0.184 20.1 PRS_PLINK_0.000199526231496888 TRUE 261.2 Vitamin B-complex deficiencies Both 21 58 3 endocrine/metabolic brown 58, 21 15, 10 14, 2 14, 4 15, 4 -0.439 0.3 0.144 0.843 0.644 0.358 1.12 -1.21 0.852 0.156 0.807 0.299 0.051 1.33 -0.903 0.801 0.259 0.586 0.405 0.0829 1.69 -0.331 0.808 0.682 0.166 0.718 0.143 3.29 PRS_PLINK_0.000199526231496888 TRUE 261.4 Vitamin D deficiency Both 188 240 3 endocrine/metabolic brown 240, 188 60, 62 60, 39 60, 35 60, 52 -0.0265 0.104 0.798 0.098 0.974 0.796 1.19 -0.337 0.286 0.239 0.622 0.714 0.411 1.23 -0.463 0.292 0.113 0.947 0.63 0.358 1.1 -0.128 0.28 0.646 0.19 0.879 0.513 1.51 PRS_PLINK_0.000199526231496888 FALSE 261.41 Rickets or osteomalacia Both 1 5 3 endocrine/metabolic brown 5, 1 2, 1 1, 0 1, 0 1, 0 0.0127 242 1 0 1.01 0.748 1.37 -0.0619 616 1 0 0.94 0.145 2.06 0.0449 551 1 0 1.05 0.808 1.79 0.0535 764 1 0 1.05 0.82 1.82 PRS_PLINK_0.000199526231496888 TRUE 262 Mineral deficiency NEC Both 32 94 3 endocrine/metabolic brown 94, 32 24, 6 23, 8 23, 9 24, 9 0.374 0.265 0.158 0.8 1.45 0.88 2.49 0.329 0.758 0.664 0.178 1.39 0.317 6.44 0.353 0.64 0.581 0.236 1.42 0.421 5.15 0.599 0.698 0.391 0.408 1.82 0.501 8.03 PRS_PLINK_0.000199526231496888 TRUE 263 Other nutritional deficiency Both 30 113 3 endocrine/metabolic brown 113, 30 29, 6 28, 4 28, 8 28, 12 0.449 0.248 0.0705 1.152 1.57 0.987 2.59 0.00596 0.763 0.994 0.003 1.01 0.209 4.47 0.549 0.64 0.391 0.408 1.73 0.519 6.32 0.582 0.607 0.338 0.471 1.79 0.571 6.05 PRS_PLINK_0.000199526231496888 TRUE 264 Lack of normal physiological development Both 2 17 3 endocrine/metabolic brown 17, 2 5, 0 4, 2 4, 0 4, 0 -0.00344 1.37 0.998 0.001 0.997 0.00527 57.8 -1.76 5.52 0.751 0.125 0.173 0.131 1360 PRS_PLINK_0.000199526231496888 TRUE 264.2 Failure to thrive (childhood) Both 2 9 3 endocrine/metabolic brown 9, 2 3, 0 2, 0 2, 2 2, 0 0.0638 4.59 0.989 0.005 1.07 4.1e-07 373000 -0.194 1760 1 0 0.824 0.125 4.38 PRS_PLINK_0.000199526231496888 TRUE 264.9 Lack of normal physiological development, unspecified Both 1 8 3 endocrine/metabolic brown 8, 1 2, 0 2, 0 2, 1 2, 0 0.653 722 0.999 0 1.92 1.84 2 -0.0442 8060000 1 0 0.957 1.14e-05 337 PRS_PLINK_0.000199526231496888 TRUE 269 Proteinuria Both 26 82 3 endocrine/metabolic brown 82, 26 21, 9 20, 6 20, 6 21, 5 0.00405 0.26 0.988 0.005 1 0.606 1.65 -0.161 0.732 0.826 0.083 0.851 0.209 3.43 -0.214 0.724 0.767 0.115 0.807 0.194 3.3 -0.318 0.699 0.649 0.188 0.728 0.184 2.68 PRS_PLINK_0.000199526231496888 TRUE 270 Disorders of protein plasma/amino-acid transport and metabolism Both 15 69 3 endocrine/metabolic brown 69, 15 18, 6 17, 2 17, 3 17, 4 -0.0535 0.31 0.863 0.064 0.948 0.524 1.79 -1.01 1.01 0.318 0.497 0.364 0.036 2.42 -0.221 0.84 0.792 0.101 0.802 0.149 4.27 -0.176 0.84 0.834 0.079 0.838 0.162 4.43 PRS_PLINK_0.000199526231496888 TRUE 270.1 Disturbances of amino-acid transport Both 3 26 3 endocrine/metabolic brown 26, 3 7, 1 6, 1 6, 0 7, 1 0.117 0.523 0.823 0.084 1.12 0.383 3.71 2.09 2.89 0.469 0.329 8.11 0.0927 21500 -0.396 1.68 0.813 0.09 0.673 0.00586 8.88 0.295 1.31 0.822 0.085 1.34 0.125 15.3 PRS_PLINK_0.000199526231496888 TRUE 270.11 Disturbances of sulphur-bearing amino-acid metabolism Both 3 23 3 endocrine/metabolic brown 23, 3 6, 1 6, 0 5, 1 6, 1 0.101 0.529 0.848 0.071 1.11 0.363 4.16 -0.952 2.12 0.653 0.185 0.386 0.00239 10.8 -0.648 2.06 0.753 0.123 0.523 0.0051 12.1 0.337 1.44 0.814 0.089 1.4 0.123 22.3 PRS_PLINK_0.000199526231496888 TRUE 270.2 Disorders of amino-acid metabolism Both 0 7 3 endocrine/metabolic brown 7, 0 2 2 1 2 PRS_PLINK_0.000199526231496888 TRUE 270.3 Disorders of plasma protein metabolism Both 12 39 3 endocrine/metabolic brown 39, 12 10, 6 10, 0 9, 2 10, 4 0.0867 0.373 0.816 0.088 1.09 0.563 2.2 -1.73 1.66 0.299 0.525 0.177 0.00178 4.27 0.267 1.17 0.82 0.086 1.31 0.164 15.4 0.266 1.01 0.792 0.102 1.3 0.211 9.34 PRS_PLINK_0.000199526231496888 TRUE 270.32 Paraproteinemia Both 7 14 3 endocrine/metabolic brown 14, 7 4, 2 3, 2 3, 3 4, 0 0.00769 0.536 0.989 0.005 1.01 0.4 2.7 2.82 4.07 0.488 0.311 16.8 0.0546 13400 2.91 3.35 0.385 0.415 18.4 0.151 20800 0.314 2.72 0.908 0.042 1.37 1.35 2.42 PRS_PLINK_0.000199526231496888 TRUE 270.33 Amyloidosis Both 0 7 3 endocrine/metabolic brown 7, 0 2 2 1 2 PRS_PLINK_0.000199526231496888 TRUE 270.34 Alpha-1-antitrypsin deficiency Both 2 5 3 endocrine/metabolic brown 5, 2 2, 0 1, 0 1, 0 1, 2 0.538 74.3 0.994 0.003 1.71 0.00252 1220 -0.294 1770 1 0 0.745 0.546 2.17 PRS_PLINK_0.000199526231496888 TRUE 270.38 Other specified disorders of plasma protein metabolism Both 4 20 3 endocrine/metabolic brown 20, 4 5, 3 5, 0 5, 0 5, 1 -0.341 0.599 0.569 0.245 0.711 0.196 2.45 -1.07 2.04 0.599 0.223 0.342 0.000288 8.49 -0.498 1.85 0.788 0.103 0.608 0.0171 27.1 -1.17 1.88 0.534 0.273 0.311 3.54e-05 5.75 PRS_PLINK_0.000199526231496888 TRUE 271 Disorders of carbohydrate transport and metabolism Both 69 208 3 endocrine/metabolic brown 208, 69 52, 17 52, 18 52, 17 52, 17 -0.0519 0.148 0.726 0.139 0.949 0.712 1.26 0.254 0.423 0.548 0.261 1.29 0.57 2.96 -0.168 0.412 0.684 0.165 0.845 0.381 1.86 -0.00251 0.434 0.995 0.002 0.997 0.43 2.3 PRS_PLINK_0.000199526231496888 FALSE 271.3 Intestinal disaccharidase deficiencies and disaccharide malabsorption Both 67 197 3 endocrine/metabolic brown 197, 67 50, 17 49, 17 49, 16 49, 17 -0.0488 0.155 0.753 0.123 0.952 0.705 1.29 0.149 0.428 0.727 0.138 1.16 0.505 2.69 -0.24 0.419 0.567 0.246 0.787 0.35 1.74 -0.0368 0.44 0.933 0.03 0.964 0.409 2.24 PRS_PLINK_0.000199526231496888 FALSE 271.9 Other disorders of carbohydrate transport and metabolism Both 3 8 3 endocrine/metabolic brown 8, 3 2, 0 2, 0 2, 1 2, 2 1.25 979 0.999 0 3.5 0.478 26 0.435 75400000 1 0 1.55 0.0136 81.2 0 7980 1 0 1 0.0668 208 PRS_PLINK_0.000199526231496888 TRUE 272 Disorders of lipoid metabolism Both 153 297 3 endocrine/metabolic brown 297, 153 74, 36 74, 43 74, 41 74, 33 0.1 0.116 0.391 0.408 1.11 0.881 1.39 0.46 0.32 0.15 0.823 1.58 0.858 2.97 0.275 0.325 0.397 0.402 1.32 0.706 2.49 0.11 0.348 0.753 0.123 1.12 0.569 2.2 PRS_PLINK_0.000199526231496888 FALSE 272.1 Hyperlipidemia Both 153 297 3 endocrine/metabolic brown 297, 153 74, 36 74, 43 74, 41 74, 33 0.1 0.116 0.391 0.408 1.11 0.881 1.39 0.46 0.32 0.15 0.823 1.58 0.858 2.97 0.275 0.325 0.397 0.402 1.32 0.706 2.49 0.11 0.348 0.753 0.123 1.12 0.569 2.2 PRS_PLINK_0.000199526231496888 FALSE 272.11 Hypercholesterolemia Both 61 176 3 endocrine/metabolic brown 176, 61 43, 17 44, 16 44, 16 44, 12 -0.00598 0.162 0.971 0.013 0.994 0.726 1.36 0.0579 0.451 0.898 0.047 1.06 0.447 2.52 0.137 0.462 0.767 0.115 1.15 0.476 2.79 -0.191 0.486 0.695 0.158 0.826 0.323 2.08 PRS_PLINK_0.000199526231496888 FALSE 272.12 Hyperglyceridemia Both 15 76 3 endocrine/metabolic brown 76, 15 19, 2 19, 6 19, 3 19, 4 0.106 0.317 0.739 0.132 1.11 0.601 2.12 1.2 0.92 0.192 0.716 3.32 0.624 26.4 0.0192 1.07 0.986 0.006 1.02 0.118 12.5 2 1.61 0.214 0.669 7.42 0.262 1.01e+09 PRS_PLINK_0.000199526231496888 TRUE 272.13 Mixed hyperlipidemia Both 38 119 3 endocrine/metabolic brown 119, 38 30, 8 30, 7 29, 14 30, 9 0.401 0.228 0.0789 1.103 1.49 0.967 2.36 0.211 0.674 0.754 0.122 1.23 0.336 4.72 1.01 0.608 0.0951 1.022 2.76 0.897 9.55 1.01 0.688 0.141 0.851 2.75 0.78 11.6 PRS_PLINK_0.000199526231496888 TRUE 272.9 Unspecified disorder of lipoid metabolism Both 12 18 3 endocrine/metabolic brown 18, 12 5, 1 4, 1 4, 7 5, 3 -0.287 0.545 0.599 0.223 0.751 0.225 2.06 -0.359 79 0.996 0.002 0.698 0.000227 6720 1.22 1.32 0.355 0.449 3.39 0.394 35.1 0.498 1.99 0.803 0.096 1.65 0.00907 1240 PRS_PLINK_0.000199526231496888 TRUE 274 Gout and other crystal arthropathies Both 32 112 3 endocrine/metabolic brown 112, 32 28, 13 28, 9 28, 9 28, 1 -0.469 0.228 0.0398 1.401 0.626 0.396 0.96 -0.294 0.534 0.581 0.236 0.745 0.268 2.02 -0.145 0.548 0.792 0.101 0.865 0.307 2.42 -2.08 0.898 0.0204 1.69 0.125 0.0121 0.604 PRS_PLINK_0.000199526231496888 TRUE 274.1 Gout Both 28 103 3 endocrine/metabolic brown 103, 28 26, 12 26, 9 25, 5 26, 2 -0.545 0.246 0.0269 1.57 0.58 0.353 0.918 -0.223 0.568 0.694 0.158 0.8 0.27 2.31 -0.688 0.636 0.279 0.554 0.502 0.141 1.61 -1.65 0.776 0.0339 1.47 0.193 0.0339 0.77 PRS_PLINK_0.000199526231496888 TRUE 274.11 Gouty arthropathy Both 17 43 3 endocrine/metabolic brown 43, 17 11, 4 11, 8 10, 3 11, 2 -0.142 0.331 0.667 0.176 0.867 0.456 1.59 1.7 1.07 0.113 0.948 5.5 0.916 59.8 0.00723 1.14 0.995 0.002 1.01 0.114 9.32 -0.0487 1.16 0.966 0.015 0.952 0.1 10.2 PRS_PLINK_0.000199526231496888 TRUE 274.2 Crystal arthropathies Both 5 10 3 endocrine/metabolic brown 10, 5 3, 1 2, 0 2, 4 3, 0 0.657 0.686 0.338 0.471 1.93 0.709 14.2 -0.175 1430 1 0 0.84 0.666 2.57 5.23 6.26 0.404 0.394 187 0.0473 253 0.0396 10700 1 0 1.04 0.127 4.57 PRS_PLINK_0.000199526231496888 TRUE 274.21 Chondrocalcinosis Both 5 7 3 endocrine/metabolic brown 7, 5 2, 1 2, 0 1, 3 2, 1 0.625 0.886 0.481 0.318 1.87 0.51 8.45 3.68 23800000 1 0 39.8 6.92e-06 17100000 2.32 123 0.985 0.007 10.2 1.43 5.11 -0.182 4960 1 0 0.833 0.0508 2.44 PRS_PLINK_0.000199526231496888 TRUE 275 Disorders of mineral metabolism Both 67 308 3 endocrine/metabolic brown 308, 67 77, 27 77, 14 77, 15 77, 11 -0.294 0.141 0.0366 1.437 0.745 0.564 0.979 -0.595 0.369 0.107 0.971 0.552 0.265 1.11 -0.296 0.377 0.432 0.365 0.744 0.354 1.54 -0.723 0.397 0.0691 1.161 0.485 0.217 1.03 PRS_PLINK_0.000199526231496888 FALSE 275.1 Disorders of iron metabolism Both 4 16 4 hematopoietic darkorange1 16, 4 4, 1 4, 1 4, 2 4, 0 -0.0988 0.593 0.868 0.062 0.906 0.325 2.59 0.192 1.96 0.922 0.035 1.21 1.04 1.37 2.2 2.29 0.337 0.473 9.03 0.328 451 0.0598 42.7 0.999 0 1.06 0.905 2.76 PRS_PLINK_0.000199526231496888 TRUE 275.11 Hereditary hemochromatosis Both 1 8 4 hematopoietic darkorange1 8, 1 2, 0 2, 0 2, 1 2, 0 -0.442 10200 1 0 0.643 0.421 0.717 -0.942 5860 1 0 0.39 0.1 6.53 PRS_PLINK_0.000199526231496888 TRUE 275.2 Disorders of copper metabolism Both 2 3 3 endocrine/metabolic brown 3, 2 1, 1 1, 0 1, 1 1, 1 1.17 10600 1 0 3.23 0.125 1590 0.551 22700 1 0 1.74 0.149 234 0.00043 52.3 1 0 1 0.958 1.04 PRS_PLINK_0.000199526231496888 TRUE 275.3 Disorders of magnesium metabolism Both 15 94 3 endocrine/metabolic brown 94, 15 24, 10 23, 4 23, 1 24, 0 -0.684 0.286 0.0169 1.773 0.504 0.274 0.866 -0.638 0.68 0.348 0.458 0.529 0.135 1.85 -1.37 0.962 0.156 0.807 0.255 0.0254 1.43 -2.89 1.28 0.0236 1.626 0.0555 0.000424 0.48 PRS_PLINK_0.000199526231496888 TRUE 275.5 Disorders of calcium/phosphorus metabolism Both 51 262 3 endocrine/metabolic brown 262, 51 66, 21 65, 8 65, 13 66, 9 -0.265 0.158 0.0943 1.025 0.767 0.561 1.04 -0.806 0.434 0.0634 1.198 0.446 0.181 1.02 -0.274 0.409 0.504 0.298 0.761 0.339 1.67 -0.685 0.435 0.116 0.936 0.504 0.208 1.15 PRS_PLINK_0.000199526231496888 FALSE 275.51 Hypocalcemia Both 15 96 3 endocrine/metabolic brown 96, 15 24, 3 24, 4 24, 3 24, 5 0.132 0.28 0.637 0.196 1.14 0.663 2.04 0.375 0.751 0.617 0.21 1.46 0.336 6.87 0.0701 0.77 0.927 0.033 1.07 0.225 5.08 0.391 0.741 0.598 0.223 1.48 0.349 6.88 PRS_PLINK_0.000199526231496888 TRUE 275.53 Disorders of phosphorus metabolism Both 20 94 3 endocrine/metabolic brown 94, 20 24, 12 23, 2 23, 3 24, 3 -0.33 0.281 0.241 0.618 0.719 0.402 1.22 -1.46 0.773 0.0585 1.233 0.232 0.0403 0.94 -0.863 0.797 0.279 0.555 0.422 0.0753 1.88 -0.841 0.776 0.278 0.556 0.431 0.088 1.8 PRS_PLINK_0.000199526231496888 TRUE 275.6 Hypercalcemia Both 19 87 3 endocrine/metabolic brown 87, 19 22, 8 22, 7 21, 2 22, 2 -0.59 0.283 0.037 1.431 0.554 0.311 0.948 -0.224 0.753 0.766 0.116 0.799 0.157 3.52 -0.736 0.786 0.349 0.457 0.479 0.086 2.14 -0.681 0.915 0.457 0.34 0.506 0.0723 2.85 PRS_PLINK_0.000199526231496888 TRUE 276 Disorders of fluid, electrolyte, and acid-base balance Both 100 350 3 endocrine/metabolic brown 350, 100 87, 35 87, 26 87, 22 88, 17 -0.18 0.119 0.13 0.886 0.835 0.66 1.05 -0.248 0.307 0.42 0.377 0.781 0.427 1.42 -0.326 0.322 0.312 0.506 0.722 0.383 1.35 -0.563 0.346 0.104 0.982 0.569 0.284 1.11 PRS_PLINK_0.000199526231496888 FALSE 276.1 Electrolyte imbalance Both 59 301 3 endocrine/metabolic brown 301, 59 75, 17 75, 18 75, 15 75, 9 -0.123 0.15 0.411 0.387 0.884 0.656 1.19 0.227 0.382 0.552 0.258 1.26 0.596 2.67 0.0787 0.413 0.849 0.071 1.08 0.478 2.46 -0.463 0.454 0.308 0.512 0.629 0.247 1.53 PRS_PLINK_0.000199526231496888 FALSE 276.11 Hyperosmolality and/or hypernatremia Both 3 29 3 endocrine/metabolic brown 29, 3 8, 1 7, 1 7, 0 7, 1 0.039 0.651 0.952 0.021 1.04 0.265 4.55 1.46 2.09 0.486 0.313 4.29 0.121 46100000 -0.0859 1.69 0.96 0.018 0.918 0.00222 115 2.2 2.38 0.356 0.448 9.01 0.179 2420 PRS_PLINK_0.000199526231496888 TRUE 276.12 Hyposmolality and/or hyponatremia Both 20 135 3 endocrine/metabolic brown 135, 20 34, 5 34, 6 33, 6 34, 3 -0.0297 0.234 0.899 0.046 0.971 0.602 1.55 0.0724 0.614 0.906 0.043 1.08 0.319 3.69 0.167 0.651 0.798 0.098 1.18 0.315 4.64 0.078 0.776 0.92 0.036 1.08 0.208 5.46 PRS_PLINK_0.000199526231496888 TRUE 276.13 Hyperpotassemia Both 29 151 3 endocrine/metabolic brown 151, 29 38, 6 38, 13 37, 7 38, 3 -0.0901 0.224 0.688 0.162 0.914 0.585 1.43 0.666 0.535 0.214 0.67 1.95 0.706 5.81 0.525 0.625 0.401 0.397 1.69 0.471 6.12 -0.461 0.746 0.536 0.271 0.631 0.123 2.91 PRS_PLINK_0.000199526231496888 TRUE 276.14 Hypopotassemia Both 18 179 3 endocrine/metabolic brown 179, 18 44, 11 45, 4 44, 0 45, 3 -0.58 0.266 0.0295 1.529 0.56 0.318 0.961 -1.6 0.709 0.0243 1.614 0.203 0.0412 0.75 -2.72 1.19 0.0218 1.661 0.0656 0.000516 0.508 -1 0.65 0.123 0.91 0.367 0.0857 1.29 PRS_PLINK_0.000199526231496888 TRUE 276.4 Acid-base balance disorder Both 23 132 3 endocrine/metabolic brown 132, 23 33, 6 33, 8 33, 8 33, 1 -0.164 0.261 0.53 0.276 0.849 0.502 1.43 0.14 0.613 0.819 0.087 1.15 0.345 3.92 0.563 0.72 0.434 0.362 1.76 0.434 10.1 -1 1.05 0.34 0.469 0.368 0.0107 3.73 PRS_PLINK_0.000199526231496888 TRUE 276.41 Acidosis Both 22 112 3 endocrine/metabolic brown 112, 22 28, 4 28, 9 28, 8 28, 1 -0.0419 0.283 0.882 0.054 0.959 0.543 1.69 0.364 0.673 0.589 0.23 1.44 0.388 5.63 0.859 0.714 0.229 0.64 2.36 0.608 11.4 -0.302 0.999 0.762 0.118 0.739 0.0141 0.949 PRS_PLINK_0.000199526231496888 TRUE 276.42 Alkalosis Both 2 35 3 endocrine/metabolic brown 35, 2 9, 0 9, 1 8, 1 9, 0 0.0829 0.646 0.898 0.047 1.09 0.126 63.2 -0.226 1.89 0.905 0.043 0.798 0.00256 504 0.977 1.59 0.539 0.269 2.66 0.137 611 PRS_PLINK_0.000199526231496888 TRUE 276.5 Hypovolemia Both 63 317 3 endocrine/metabolic brown 317, 63 79, 24 79, 14 79, 13 79, 12 -0.186 0.142 0.19 0.722 0.83 0.626 1.1 -0.708 0.393 0.0718 1.144 0.493 0.22 1.05 -0.515 0.392 0.189 0.724 0.598 0.271 1.28 -0.603 0.41 0.141 0.85 0.547 0.238 1.2 PRS_PLINK_0.000199526231496888 FALSE 276.6 Fluid overload Both 9 69 3 endocrine/metabolic brown 69, 9 18, 3 17, 2 17, 2 17, 2 -0.162 0.447 0.717 0.144 0.85 0.3 2.48 -0.478 0.999 0.632 0.199 0.62 0.0395 5.1 -0.55 1.06 0.603 0.219 0.577 0.0385 6.03 -0.311 1 0.756 0.122 0.733 0.0577 6.95 PRS_PLINK_0.000199526231496888 TRUE 276.8 Polydipsia Both 3 11 3 endocrine/metabolic brown 11, 3 3, 1 3, 2 2, 0 3, 0 -0.558 0.874 0.523 0.282 0.572 0.0348 3.57 0.562 3.67 0.878 0.056 1.75 0.00676 1220 -0.0445 969 1 0 0.956 0.583 1.41 -1.01 6.57 0.878 0.056 0.365 0.343 0.387 PRS_PLINK_0.000199526231496888 TRUE 277 Other disorders of metabolism Both 98 324 3 endocrine/metabolic brown 324, 98 81, 28 81, 18 81, 18 81, 33 0.0225 0.122 0.853 0.069 1.02 0.808 1.3 -0.48 0.353 0.174 0.759 0.619 0.307 1.22 -0.357 0.355 0.313 0.504 0.699 0.347 1.39 0.0907 0.323 0.779 0.109 1.09 0.586 2.05 PRS_PLINK_0.000199526231496888 FALSE 277.2 Other disorders of purine and pyrimidine metabolism Both 9 16 3 endocrine/metabolic brown 16, 9 4, 2 4, 1 4, 1 4, 5 0.318 0.53 0.549 0.261 1.37 0.566 3.82 0.31 9.5 0.974 0.011 1.36 6.37e-07 2.91e+08 2.32 5.49 0.673 0.172 10.1 8.89 11.6 1.44 1.71 0.398 0.4 4.22 0.368 2780 PRS_PLINK_0.000199526231496888 TRUE 277.4 Disorders of bilirubin excretion Both 7 47 3 endocrine/metabolic brown 47, 7 12, 2 12, 1 11, 2 12, 2 -0.117 0.513 0.82 0.086 0.889 0.302 2.48 0.51 1.38 0.712 0.147 1.67 0.119 34.4 -0.00493 1.32 0.997 0.001 0.995 0.0425 14.6 -0.0273 1.05 0.979 0.009 0.973 0.0951 7.56 PRS_PLINK_0.000199526231496888 TRUE 277.5 Other disorders of lipoid metabolism Both 25 75 3 endocrine/metabolic brown 75, 25 19, 4 19, 4 18, 5 19, 11 0.151 0.212 0.477 0.322 1.16 0.777 1.77 -0.0607 0.866 0.944 0.025 0.941 0.139 5.01 0.386 0.933 0.679 0.168 1.47 0.226 9.6 0.709 0.727 0.329 0.482 2.03 0.53 8.36 PRS_PLINK_0.000199526231496888 TRUE 277.51 Lipoprotein disorders Both 16 61 3 endocrine/metabolic brown 61, 16 16, 5 15, 1 15, 2 15, 7 -0.106 0.285 0.712 0.148 0.9 0.513 1.56 -1.12 1.19 0.347 0.459 0.327 0.0188 2.8 -0.676 0.942 0.473 0.325 0.509 0.0627 2.72 -0.429 0.897 0.632 0.199 0.651 0.107 3.36 PRS_PLINK_0.000199526231496888 TRUE 277.7 Dysmetabolic syndrome X Both 29 65 3 endocrine/metabolic brown 65, 29 17, 9 16, 5 16, 5 16, 10 0.0447 0.234 0.848 0.072 1.05 0.672 1.63 -0.933 0.778 0.23 0.638 0.393 0.0839 1.56 -0.611 0.711 0.39 0.409 0.543 0.133 1.98 -0.332 0.689 0.63 0.201 0.718 0.185 2.5 PRS_PLINK_0.000199526231496888 TRUE 278 Overweight, obesity and other hyperalimentation Both 270 183 3 endocrine/metabolic brown 183, 270 46, 78 46, 53 45, 54 46, 84 -0.0213 0.1 0.831 0.08 0.979 0.805 1.19 -0.417 0.283 0.141 0.851 0.659 0.381 1.13 -0.419 0.287 0.145 0.839 0.658 0.376 1.14 0.0191 0.274 0.944 0.025 1.02 0.6 1.73 PRS_PLINK_0.000199526231496888 FALSE 278.1 Obesity Both 230 183 3 endocrine/metabolic brown 183, 230 46, 69 46, 44 45, 44 46, 72 -0.0233 0.106 0.826 0.083 0.977 0.795 1.2 -0.446 0.298 0.135 0.871 0.64 0.359 1.13 -0.49 0.299 0.102 0.993 0.613 0.343 1.09 0.0324 0.286 0.91 0.041 1.03 0.595 1.79 PRS_PLINK_0.000199526231496888 FALSE 278.11 Morbid obesity Both 141 183 3 endocrine/metabolic brown 183, 141 46, 44 46, 33 45, 24 46, 40 -0.113 0.124 0.361 0.442 0.893 0.702 1.13 -0.305 0.333 0.36 0.444 0.737 0.387 1.39 -0.804 0.36 0.0255 1.593 0.447 0.219 0.885 -0.0539 0.328 0.869 0.061 0.948 0.505 1.78 PRS_PLINK_0.000199526231496888 FALSE 278.3 Localized adiposity Both 4 28 3 endocrine/metabolic brown 28, 4 7, 4 7, 0 7, 0 7, 0 -1.71 0.963 0.0759 1.12 0.181 0.009 1.03 -1.92 1.51 0.206 0.687 0.147 0.00132 1.63 -2.42 1.76 0.169 0.772 0.0888 0.000175 1.39 -1.92 1.74 0.271 0.568 0.147 0.000321 2.44 PRS_PLINK_0.000199526231496888 TRUE 278.4 Abnormal weight gain Both 70 149 3 endocrine/metabolic brown 149, 70 38, 18 37, 13 37, 12 37, 27 0.2 0.157 0.203 0.693 1.22 0.906 1.66 -0.339 0.494 0.493 0.307 0.713 0.273 1.8 -0.469 0.485 0.333 0.478 0.626 0.243 1.55 0.309 0.426 0.468 0.33 1.36 0.612 3.08 PRS_PLINK_0.000199526231496888 FALSE 279 Disorders involving the immune mechanism Both 67 225 3 endocrine/metabolic brown 225, 67 56, 25 56, 21 56, 8 56, 13 -0.0782 0.157 0.618 0.209 0.925 0.68 1.26 -0.0328 0.397 0.934 0.03 0.968 0.45 2.08 -0.745 0.462 0.107 0.97 0.475 0.186 1.14 -0.27 0.451 0.549 0.261 0.763 0.314 1.83 PRS_PLINK_0.000199526231496888 FALSE 279.1 Immunity deficiency Both 30 100 3 endocrine/metabolic brown 100, 30 25, 11 25, 11 25, 4 25, 4 -0.12 0.284 0.672 0.172 0.887 0.501 1.56 -0.0827 0.684 0.904 0.044 0.921 0.239 3.5 -0.314 0.728 0.666 0.176 0.731 0.168 3.06 0.121 0.935 0.897 0.047 1.13 0.17 7.54 PRS_PLINK_0.000199526231496888 TRUE 279.11 Deficiency of humoral immunity Both 4 14 3 endocrine/metabolic brown 14, 4 4, 1 3, 2 3, 1 4, 0 -0.0187 0.978 0.985 0.007 0.981 0.325 3.32 0.121 777 1 0 1.13 0.301 2.4 -0.0622 749 1 0 0.94 0.717 14.1 0.401 2890 1 0 1.49 0.51 2.06 PRS_PLINK_0.000199526231496888 TRUE 279.2 Autoimmune disease NEC Both 13 68 3 endocrine/metabolic brown 68, 13 17, 2 17, 5 17, 3 17, 3 0.159 0.369 0.668 0.175 1.17 0.57 2.49 0.0239 1 0.981 0.008 1.02 0.149 7.98 1.37 1.59 0.39 0.409 3.93 0.209 8.59e+09 0.851 1.11 0.443 0.353 2.34 0.298 23.2 PRS_PLINK_0.000199526231496888 TRUE 279.7 Other immunological findings Both 117 290 3 endocrine/metabolic brown 290, 117 72, 40 72, 33 72, 17 73, 27 -0.145 0.12 0.227 0.643 0.865 0.684 1.09 -0.0823 0.304 0.787 0.104 0.921 0.513 1.65 -0.817 0.354 0.0211 1.676 0.442 0.218 0.865 -0.255 0.327 0.435 0.362 0.775 0.41 1.45 PRS_PLINK_0.000199526231496888 FALSE 279.8 Other specified disorders involving the immune mechanism Both 12 58 3 endocrine/metabolic brown 58, 12 15, 1 14, 6 14, 2 15, 3 0.404 0.47 0.39 0.409 1.5 0.614 4.18 1.16 1.15 0.314 0.503 3.2 0.417 77.1 0.0703 1.45 0.961 0.017 1.07 0.0159 35.2 2.94 1.94 0.129 0.889 18.9 0.619 2.41e+09 PRS_PLINK_0.000199526231496888 TRUE 280 Iron deficiency anemias Both 79 263 4 hematopoietic darkorange1 263, 79 66, 32 66, 19 65, 16 66, 12 -0.253 0.135 0.0619 1.209 0.777 0.594 1.01 -0.437 0.355 0.218 0.661 0.646 0.322 1.28 -0.625 0.363 0.0852 1.07 0.535 0.26 1.08 -0.947 0.392 0.0156 1.807 0.388 0.175 0.816 PRS_PLINK_0.000199526231496888 FALSE 280.1 Iron deficiency anemias, unspecified or not due to blood loss Both 78 263 4 hematopoietic darkorange1 263, 78 66, 32 66, 19 65, 15 66, 12 -0.263 0.136 0.0529 1.277 0.768 0.587 1 -0.437 0.355 0.218 0.661 0.646 0.322 1.28 -0.703 0.369 0.0572 1.243 0.495 0.236 1.01 -0.947 0.392 0.0156 1.807 0.388 0.175 0.816 PRS_PLINK_0.000199526231496888 FALSE 280.2 Iron deficiency anemia secondary to blood loss (chronic) Both 25 144 4 hematopoietic darkorange1 144, 25 36, 4 36, 9 36, 6 36, 6 0.158 0.244 0.519 0.285 1.17 0.726 1.92 0.82 0.7 0.241 0.617 2.27 0.604 9.94 0.524 0.677 0.439 0.358 1.69 0.464 6.74 0.595 0.663 0.369 0.433 1.81 0.501 7.42 PRS_PLINK_0.000199526231496888 TRUE 281 Other deficiency anemia Both 9 39 4 hematopoietic darkorange1 39, 9 10, 2 10, 4 9, 1 10, 1 -0.601 0.437 0.169 0.771 0.548 0.226 1.2 0.355 1 0.723 0.141 1.43 0.228 10.3 -0.272 1.2 0.821 0.086 0.762 0.0245 7.73 -0.359 1.56 0.818 0.087 0.698 0.00117 22.6 PRS_PLINK_0.000199526231496888 TRUE 281.1 Megaloblastic anemia Both 8 25 4 hematopoietic darkorange1 25, 8 7, 2 6, 4 6, 0 6, 1 -0.632 0.452 0.162 0.79 0.531 0.21 1.13 0.49 1.11 0.658 0.182 1.63 0.255 11.5 -1.32 1.74 0.45 0.347 0.268 0.000493 5.55 -1.41 1.78 0.43 0.366 0.245 9.94e-08 3.54 PRS_PLINK_0.000199526231496888 TRUE 281.11 Pernicious anemia Both 4 9 4 hematopoietic darkorange1 9, 4 3, 2 2, 1 2, 0 2, 0 -0.161 175 0.999 0 0.851 0.503 1.59 -0.0276 593 1 0 0.973 0.824 1.18 -1.03 54.9 0.985 0.007 0.358 0.0277 2.06 -1.78 170 0.992 0.004 0.169 0.0376 0.0691 PRS_PLINK_0.000199526231496888 TRUE 281.12 Other vitamin B12 deficiency anemia Both 6 17 4 hematopoietic darkorange1 17, 6 5, 0 4, 4 4, 0 4, 1 -0.11 40.1 0.998 0.001 0.896 0.799 1.27 0.473 1.61 0.769 0.114 1.6 0.325 7.79 0.985 4.69 0.834 0.079 2.68 0.00134 14200 PRS_PLINK_0.000199526231496888 TRUE 281.9 Deficiency anemias Both 1 15 4 hematopoietic darkorange1 15, 1 4, 0 4, 1 3, 0 4, 0 0.528 2.94 0.857 0.067 1.69 0.00211 42800 0.364 348 0.999 0 1.44 2.81 4.56 PRS_PLINK_0.000199526231496888 TRUE 282 Hereditary hemolytic anemias Both 1 27 4 hematopoietic darkorange1 27, 1 7, 0 7, 0 6, 1 7, 0 -0.17 0.759 0.822 0.085 0.843 0.0107 4.45 -0.0278 1.9 0.988 0.005 0.973 0.00863 66.8 PRS_PLINK_0.000199526231496888 TRUE 282.8 Other hemoglobinopathies Both 0 15 4 hematopoietic darkorange1 15, 0 4 4 3 4 PRS_PLINK_0.000199526231496888 TRUE 282.9 Other hereditary hemolytic anemias Both 1 12 4 hematopoietic darkorange1 12, 1 3, 0 3, 0 3, 1 3, 0 -0.0267 0.913 0.977 0.01 0.974 0.105 6.13 0.408 495 0.999 0 1.5 2.95 3.48 PRS_PLINK_0.000199526231496888 TRUE 283 Acquired hemolytic anemias Both 3 15 4 hematopoietic darkorange1 15, 3 4, 2 4, 0 3, 1 4, 0 -0.869 1.47 0.553 0.257 0.419 6.96e-08 4.46 -4.65 132 0.972 0.012 0.00951 0.00713 0.0127 13.7 326 0.966 0.015 905000 8.24e+10 1.18e+10 -3.78 45.6 0.934 0.03 0.0228 0.0169 0.0323 PRS_PLINK_0.000199526231496888 TRUE 283.1 Autoimmune hemolytic anemias Both 0 4 4 hematopoietic darkorange1 4, 0 1 1 1 1 PRS_PLINK_0.000199526231496888 TRUE 284 Aplastic anemia Both 8 45 4 hematopoietic darkorange1 45, 8 12, 4 11, 3 11, 1 11, 0 -1.82 0.907 0.0443 1.354 0.161 0.00101 0.718 -0.491 1.44 0.734 0.134 0.612 0.000484 37.3 0.776 1.99 0.696 0.157 2.17 0.0101 127000 -2.79 1.71 0.103 0.987 0.0613 0.000146 0.94 PRS_PLINK_0.000199526231496888 TRUE 284.1 Pancytopenia Both 8 41 4 hematopoietic darkorange1 41, 8 11, 4 10, 3 10, 1 10, 0 -1.79 0.894 0.0455 1.342 0.167 0.000942 0.715 -0.388 1.49 0.794 0.1 0.678 0.001 42.4 0.583 2.4 0.808 0.093 1.79 0.00858 1.47e+12 -3.17 1.9 0.0949 1.023 0.042 0.000114 0.943 PRS_PLINK_0.000199526231496888 TRUE 285 Other anemias Both 165 268 4 hematopoietic darkorange1 268, 165 67, 51 67, 40 67, 37 67, 36 -0.114 0.102 0.263 0.58 0.892 0.732 1.09 -0.189 0.288 0.512 0.291 0.828 0.474 1.44 -0.231 0.29 0.426 0.371 0.794 0.453 1.39 -0.297 0.292 0.31 0.509 0.743 0.422 1.3 PRS_PLINK_0.000199526231496888 FALSE 285.1 Acute posthemorrhagic anemia Both 40 204 4 hematopoietic darkorange1 204, 40 51, 11 51, 15 51, 8 51, 6 -0.329 0.184 0.0733 1.135 0.719 0.496 1.03 0.125 0.462 0.786 0.104 1.13 0.461 2.81 -0.274 0.52 0.598 0.223 0.76 0.263 2.13 -0.546 0.544 0.316 0.501 0.579 0.185 1.66 PRS_PLINK_0.000199526231496888 TRUE 285.2 Anemia of chronic disease Both 32 121 4 hematopoietic darkorange1 121, 32 31, 12 30, 3 30, 10 30, 7 0.0822 0.206 0.69 0.161 1.09 0.726 1.64 -0.926 0.686 0.177 0.753 0.396 0.0903 1.45 0.268 0.583 0.645 0.19 1.31 0.431 4.21 -0.0674 0.605 0.911 0.04 0.935 0.283 3.11 PRS_PLINK_0.000199526231496888 TRUE 285.21 Anemia in chronic kidney disease Both 28 47 4 hematopoietic darkorange1 47, 28 12, 8 12, 8 11, 6 12, 6 0.15 0.314 0.633 0.199 1.16 0.638 2.23 -0.154 0.918 0.867 0.062 0.858 0.128 5 1.03 1.15 0.372 0.429 2.79 0.35 35.7 0.401 0.926 0.665 0.177 1.49 0.28 11.2 PRS_PLINK_0.000199526231496888 TRUE 285.22 Anemia in neoplastic disease Both 5 46 4 hematopoietic darkorange1 46, 5 12, 1 11, 1 11, 2 12, 1 -0.0727 0.461 0.875 0.058 0.93 0.344 2.24 0.0697 1.47 0.962 0.017 1.07 0.012 115 1.64 1.6 0.307 0.513 5.14 0.349 1030 -0.497 1.41 0.723 0.141 0.608 0.0133 15.2 PRS_PLINK_0.000199526231496888 TRUE 286 Coagulation defects Both 49 297 4 hematopoietic darkorange1 297, 49 74, 12 74, 12 74, 13 74, 12 0.0347 0.155 0.823 0.085 1.04 0.763 1.41 0.0586 0.442 0.894 0.048 1.06 0.439 2.56 -0.0466 0.445 0.917 0.038 0.955 0.395 2.29 0.22 0.435 0.613 0.212 1.25 0.525 2.97 PRS_PLINK_0.000199526231496888 TRUE 286.1 Congenital coagulation defects Both 5 28 4 hematopoietic darkorange1 28, 5 7, 1 7, 2 7, 0 7, 2 -0.0605 0.515 0.907 0.043 0.941 0.375 2.6 1.12 1.49 0.45 0.347 3.07 0.239 76.2 -0.124 1.97 0.95 0.022 0.883 0.00432 338 0.811 2.29 0.723 0.141 2.25 0.0644 308 PRS_PLINK_0.000199526231496888 TRUE 286.11 Von willebrand's disease Both 3 14 4 hematopoietic darkorange1 14, 3 4, 1 3, 1 3, 0 4, 1 -0.763 1.44 0.597 0.224 0.466 0.00719 7.18 1.16 80.2 0.988 0.005 3.18 2.98 3.4 0.0587 43.6 0.999 0 1.06 0.406 3.97 -1.78 20.2 0.93 0.032 0.168 0.149 0.19 PRS_PLINK_0.000199526231496888 TRUE 286.12 Congenital deficiency of other clotting factors (including factor VII) Both 2 14 4 hematopoietic darkorange1 14, 2 4, 1 3, 0 3, 0 4, 1 1.65 1.71 0.337 0.473 5.19 0.349 1160 -1.7e-12 22.8 1 0 1 0.958 15.5 4.21e-12 40.7 1 0 1 0.942 46 -0.282 44.4 0.995 0.002 0.754 0.962 1.62 PRS_PLINK_0.000199526231496888 TRUE 286.2 Encounter for long-term (current) use of anticoagulants Both 35 160 4 hematopoietic darkorange1 160, 35 39, 8 40, 9 40, 8 40, 10 0.139 0.197 0.48 0.318 1.15 0.787 1.69 0.801 0.634 0.206 0.685 2.23 0.653 8.49 0.114 0.582 0.845 0.073 1.12 0.36 3.55 0.38 0.556 0.495 0.306 1.46 0.506 4.42 PRS_PLINK_0.000199526231496888 TRUE 286.3 Coagulation defects complicating pregnancy or postpartum Female 17 33 4 hematopoietic darkorange1 33, 17 9, 8 8, 1 8, 4 8, 4 -0.163 0.337 0.63 0.201 0.85 0.441 1.6 -1.46 1.2 0.223 0.652 0.233 0.0144 1.7 -0.176 0.904 0.846 0.073 0.839 0.15 4.23 -0.576 0.912 0.528 0.278 0.562 0.0902 2.74 PRS_PLINK_0.000199526231496888 TRUE 286.4 Acquired coagulation factor deficiency Both 2 20 4 hematopoietic darkorange1 20, 2 5, 2 5, 0 5, 0 5, 0 -0.617 0.885 0.486 0.314 0.54 6.73e-06 2.41 -0.916 2.48 0.712 0.148 0.4 0.000906 17.3 -1.15 2.21 0.601 0.221 0.315 0.00291 10.1 -0.513 2.4 0.831 0.08 0.599 0.00454 386 PRS_PLINK_0.000199526231496888 TRUE 286.5 Hemorrhagic disorder due to intrinsic circulating anticoagulants Both 2 9 4 hematopoietic darkorange1 9, 2 3, 1 2, 0 2, 1 2, 0 -0.71 1.18 0.548 0.261 0.492 0.00986 3.46 0.0525 252 1 0 1.05 0.782 1.5 -1.41 1110 0.999 0 0.244 0.084 0.825 -0.0324 6530 1 0 0.968 0.565 9.04 PRS_PLINK_0.000199526231496888 TRUE 286.6 Defibrination syndrome Both 36 227 4 hematopoietic darkorange1 227, 36 56, 9 57, 6 56, 10 57, 11 0.0792 0.177 0.654 0.185 1.08 0.764 1.54 -0.389 0.569 0.495 0.305 0.678 0.207 2.07 0.0263 0.506 0.958 0.018 1.03 0.377 2.79 0.341 0.484 0.481 0.318 1.41 0.543 3.7 PRS_PLINK_0.000199526231496888 TRUE 286.7 Other and unspecified coagulation defects Both 41 273 4 hematopoietic darkorange1 273, 41 68, 12 68, 7 68, 11 68, 11 0.0284 0.163 0.862 0.065 1.03 0.745 1.43 -0.505 0.506 0.318 0.497 0.603 0.208 1.62 -0.141 0.452 0.756 0.122 0.869 0.352 2.11 0.112 0.445 0.802 0.096 1.12 0.461 2.7 PRS_PLINK_0.000199526231496888 TRUE 286.8 Hypercoagulable state Both 24 90 4 hematopoietic darkorange1 90, 24 23, 7 22, 4 22, 5 23, 8 0.0441 0.245 0.857 0.067 1.05 0.651 1.67 -1 0.911 0.27 0.568 0.366 0.043 1.93 -0.262 0.737 0.722 0.142 0.769 0.18 3.05 0.257 0.628 0.682 0.166 1.29 0.404 4.25 PRS_PLINK_0.000199526231496888 TRUE 286.81 Primary hypercoagulable state Both 22 84 4 hematopoietic darkorange1 84, 22 21, 7 21, 2 21, 5 21, 8 0.202 0.268 0.451 0.346 1.22 0.735 2.07 -1.26 0.949 0.183 0.738 0.283 0.0285 1.58 -0.269 0.749 0.72 0.143 0.764 0.177 3.13 0.293 0.658 0.656 0.183 1.34 0.401 4.66 PRS_PLINK_0.000199526231496888 TRUE 286.9 Abnormal coagulation profile Both 10 70 4 hematopoietic darkorange1 70, 10 18, 2 17, 3 17, 4 18, 1 -0.0026 0.356 0.994 0.003 0.997 0.467 1.98 2.83 1.55 0.0684 1.165 16.9 0.911 2780 0.572 0.957 0.55 0.26 1.77 0.241 14.2 0.762 1.22 0.532 0.274 2.14 0.165 300 PRS_PLINK_0.000199526231496888 TRUE 287 Purpura and other hemorrhagic conditions Both 39 190 4 hematopoietic darkorange1 190, 39 48, 13 47, 13 47, 8 48, 5 -0.278 0.192 0.147 0.833 0.757 0.518 1.1 0.0867 0.505 0.864 0.064 1.09 0.413 2.92 -0.405 0.521 0.437 0.36 0.667 0.233 1.81 -0.755 0.561 0.178 0.749 0.47 0.145 1.34 PRS_PLINK_0.000199526231496888 TRUE 287.1 Spontaneous ecchymoses Both 2 17 4 hematopoietic darkorange1 17, 2 4, 1 4, 0 4, 0 4, 1 -0.119 0.689 0.862 0.064 0.887 0.469 2.42 0.303 2630 1 0 1.35 0.139 14.3 -3.72 15.4 0.809 0.092 0.0242 8.13e-16 1.38e+10 0.378 4.54 0.934 0.03 1.46 1.21 1.89 PRS_PLINK_0.000199526231496888 TRUE 287.3 Thrombocytopenia Both 33 170 4 hematopoietic darkorange1 170, 33 43, 11 42, 11 42, 7 43, 4 -0.261 0.206 0.206 0.686 0.77 0.512 1.15 0.108 0.547 0.844 0.074 1.11 0.384 3.26 -0.238 0.544 0.661 0.18 0.788 0.266 2.26 -0.73 0.612 0.233 0.633 0.482 0.129 1.52 PRS_PLINK_0.000199526231496888 TRUE 287.31 Primary thrombocytopenia Both 7 43 4 hematopoietic darkorange1 43, 7 11, 3 11, 3 10, 1 11, 0 -0.574 0.501 0.252 0.598 0.563 0.164 1.47 -0.337 1.17 0.773 0.112 0.714 0.0461 5.97 -0.419 1.2 0.726 0.139 0.658 0.0425 5.97 -3.71 2.5 0.139 0.858 0.0245 4.06e-06 1.53 PRS_PLINK_0.000199526231496888 TRUE 287.32 Secondary thrombocytopenia Both 1 35 4 hematopoietic darkorange1 35, 1 9, 0 9, 0 8, 1 9, 0 0.0668 0.936 0.943 0.025 1.07 0.104 39.2 -0.262 2.04 0.898 0.047 0.769 0.000614 139 PRS_PLINK_0.000199526231496888 TRUE 287.4 Qualitative platelet defects Both 1 11 4 hematopoietic darkorange1 11, 1 3, 0 3, 0 2, 0 3, 1 1.48 4.25 0.728 0.138 4.39 0.0914 432 0.337 4240 1 0 1.4 0.453 6.03 PRS_PLINK_0.000199526231496888 TRUE 288 Diseases of white blood cells Both 63 321 4 hematopoietic darkorange1 321, 63 80, 15 80, 20 80, 14 80, 14 -0.00788 0.146 0.957 0.019 0.992 0.746 1.32 0.167 0.394 0.671 0.173 1.18 0.546 2.58 0.00118 0.416 0.998 0.001 1 0.441 2.27 -0.0669 0.424 0.875 0.058 0.935 0.406 2.14 PRS_PLINK_0.000199526231496888 FALSE 288.1 Decreased white blood cell count Both 28 127 4 hematopoietic darkorange1 127, 28 32, 9 32, 6 31, 8 32, 5 -0.147 0.239 0.54 0.268 0.864 0.54 1.37 -0.576 0.7 0.411 0.386 0.562 0.137 2.12 -0.0718 0.603 0.905 0.043 0.931 0.287 2.98 -1.23 0.909 0.177 0.753 0.293 0.0421 1.61 PRS_PLINK_0.000199526231496888 TRUE 288.11 Neutropenia Both 18 85 4 hematopoietic darkorange1 85, 18 22, 4 21, 6 21, 4 21, 4 0.0327 0.301 0.913 0.039 1.03 0.57 1.88 0.12 0.882 0.891 0.05 1.13 0.2 6.45 -0.0395 0.779 0.96 0.018 0.961 0.205 4.33 -0.293 1.38 0.832 0.08 0.746 2.16e-05 18.5 PRS_PLINK_0.000199526231496888 TRUE 288.2 Elevated white blood cell count Both 52 296 4 hematopoietic darkorange1 296, 52 74, 12 74, 15 74, 14 74, 11 0.0179 0.162 0.912 0.04 1.02 0.741 1.4 0.151 0.436 0.73 0.137 1.16 0.491 2.78 0.125 0.442 0.778 0.109 1.13 0.475 2.73 -0.249 0.471 0.598 0.223 0.78 0.304 1.96 PRS_PLINK_0.000199526231496888 FALSE 288.3 Eosinophilia Both 3 11 4 hematopoietic darkorange1 11, 3 3, 1 3, 0 2, 0 3, 2 0.0787 176 1 0 1.08 0.446 1.71 -0.0192 1280 1 0 0.981 0.654 1.41 1.39e-06 7050 1 0 1 0.273 7.79 -0.041 561 1 0 0.96 0.939 0.991 PRS_PLINK_0.000199526231496888 TRUE 289 Other diseases of blood and blood-forming organs Both 36 146 4 hematopoietic darkorange1 146, 36 37, 12 36, 13 36, 5 37, 6 -0.265 0.204 0.194 0.712 0.767 0.511 1.13 0.0788 0.536 0.883 0.054 1.08 0.381 3.08 -0.808 0.582 0.165 0.783 0.446 0.134 1.33 -0.588 0.594 0.322 0.492 0.555 0.164 1.7 PRS_PLINK_0.000199526231496888 TRUE 289.3 Personal history of diseases of blood and blood-forming organs Both 29 89 4 hematopoietic darkorange1 89, 29 22, 10 22, 7 22, 3 22, 9 0.0286 0.251 0.909 0.041 1.03 0.64 1.67 -0.342 0.67 0.61 0.215 0.71 0.176 3.06 -0.886 0.722 0.22 0.658 0.412 0.0896 1.55 0.122 0.613 0.843 0.074 1.13 0.361 3.65 PRS_PLINK_0.000199526231496888 TRUE 289.4 Lymphadenitis Both 50 305 4 hematopoietic darkorange1 305, 50 76, 14 76, 16 76, 8 76, 12 -0.153 0.155 0.322 0.492 0.858 0.632 1.17 0.0741 0.403 0.854 0.069 1.08 0.488 2.39 -0.598 0.461 0.194 0.712 0.55 0.212 1.35 -0.293 0.443 0.508 0.294 0.746 0.307 1.76 PRS_PLINK_0.000199526231496888 TRUE 289.5 Diseases of spleen Both 6 32 4 hematopoietic darkorange1 32, 6 8, 1 8, 0 8, 4 8, 1 -0.264 0.67 0.693 0.159 0.768 0.126 3.04 0.821 1.93 0.67 0.174 2.27 0.0259 352 0.209 1.33 0.876 0.058 1.23 1.05 1620 2.34 2.29 0.307 0.513 10.3 0.219 1030 PRS_PLINK_0.000199526231496888 TRUE 289.8 Polycythemia, secondary Both 4 9 4 hematopoietic darkorange1 9, 4 3, 3 2, 0 2, 0 2, 1 -0.792 2.65 0.765 0.116 0.453 0.000111 31.5 -0.669 314 0.998 0.001 0.512 0.03 136 0.0412 1310 1 0 1.04 0.629 1.18 2.79 395 0.994 0.002 16.3 3.09 7.83 PRS_PLINK_0.000199526231496888 TRUE 289.9 Abnormality of red blood cells Both 4 35 4 hematopoietic darkorange1 35, 4 9, 2 9, 1 8, 0 9, 1 -0.168 0.492 0.733 0.135 0.846 0.275 2.14 -1.08 1.67 0.517 0.287 0.338 0.000131 62.9 -1.28 1.57 0.416 0.381 0.279 0.00386 3.77 -0.432 1.28 0.735 0.134 0.649 0.0399 24.4 PRS_PLINK_0.000199526231496888 TRUE 290 Delirium dementia and amnestic and other cognitive disorders Both 7 48 5 mental disorders magenta 48, 7 12, 1 12, 3 12, 2 12, 1 -0.0403 0.381 0.916 0.038 0.961 0.459 2.01 -0.161 1.25 0.898 0.047 0.852 0.0252 9.58 -2.08 2.05 0.309 0.51 0.125 1.25e-06 5.41 -0.572 1.43 0.689 0.162 0.565 0.00489 12.6 PRS_PLINK_0.000199526231496888 TRUE 290.1 Dementias Both 2 10 5 mental disorders magenta 10, 2 3, 0 2, 0 2, 0 3, 2 1.06 1.22 0.383 0.417 2.89 0.58 24 -0.154 1920 1 0 0.858 0.409 0.989 PRS_PLINK_0.000199526231496888 TRUE 290.11 Alzheimer's disease Both 1 5 5 mental disorders magenta 5, 1 2, 0 1, 0 1, 0 1, 1 -4.26 1240 0.997 0.001 0.0141 3.53e-13 1e+09 -0.132 134000 1 0 0.876 0.183 4.15 PRS_PLINK_0.000199526231496888 TRUE 290.12 Dementia with cerebral degenerations Both 2 0 5 mental disorders magenta 0, 2 PRS_PLINK_0.000199526231496888 TRUE 290.13 Senile dementia Both 1 3 5 mental disorders magenta 3, 1 1, 0 1, 0 1, 1 1, 0 0.00367 967 1 0 1 0.925 1.11 0.00118 20.2 1 0 1 0.982 1.02 PRS_PLINK_0.000199526231496888 TRUE 290.16 Vascular dementia Both 1 3 5 mental disorders magenta 3, 1 1, 0 1, 0 1, 1 1, 0 0.117 7500 1 0 1.12 0.521 2.73 0.336 18900 1 0 1.4 0.514 2.07 PRS_PLINK_0.000199526231496888 TRUE 290.2 Delirium due to conditions classified elsewhere Both 4 35 5 mental disorders magenta 35, 4 9, 1 9, 3 8, 0 9, 0 -0.96 0.635 0.131 0.884 0.383 0.0317 1.15 0.602 1.4 0.667 0.176 1.83 0.0806 285 -0.36 1.97 0.855 0.068 0.697 0.00274 146 -0.497 1.51 0.742 0.13 0.609 0.0131 25.3 PRS_PLINK_0.000199526231496888 TRUE 290.3 Other persistent mental disorders due to conditions classified elsewhere Both 11 44 5 mental disorders magenta 44, 11 11, 4 11, 2 11, 2 11, 3 -0.125 0.511 0.807 0.093 0.883 0.319 2.39 0.0835 1.13 0.941 0.026 1.09 0.119 8.18 -0.777 1.16 0.503 0.299 0.46 0.0337 4.73 -0.512 1.18 0.664 0.178 0.6 0.0627 5.97 PRS_PLINK_0.000199526231496888 TRUE 291 Other specified nonpsychotic and/or transient mental disorders Both 53 209 5 mental disorders magenta 209, 53 53, 17 52, 8 52, 15 52, 13 -0.0752 0.162 0.643 0.191 0.928 0.676 1.27 -0.809 0.487 0.0969 1.014 0.446 0.164 1.12 -0.116 0.413 0.779 0.109 0.89 0.4 1.97 -0.338 0.426 0.428 0.368 0.713 0.31 1.6 PRS_PLINK_0.000199526231496888 FALSE 291.1 Transient mental disorders due to conditions classified elsewhere Both 21 44 5 mental disorders magenta 44, 21 11, 6 11, 3 11, 5 11, 7 -0.112 0.325 0.729 0.137 0.894 0.484 1.62 -0.446 1.21 0.711 0.148 0.64 0.0616 5.06 -0.612 0.935 0.513 0.29 0.542 0.0796 2.99 -0.416 1.05 0.693 0.159 0.66 0.0787 4.63 PRS_PLINK_0.000199526231496888 TRUE 291.4 Specific nonpsychotic mental disorders due to brain damage Both 7 44 5 mental disorders magenta 44, 7 11, 2 11, 1 11, 1 11, 3 -0.0695 0.467 0.882 0.055 0.933 0.365 2.47 -0.766 1.2 0.522 0.283 0.465 0.0184 3.81 -0.0998 1.31 0.939 0.027 0.905 0.0733 22.8 -0.335 1.29 0.794 0.1 0.715 0.0383 7.67 PRS_PLINK_0.000199526231496888 TRUE 291.8 Alteration of consciousness Both 26 152 5 mental disorders magenta 152, 26 38, 10 38, 6 38, 7 38, 3 -0.287 0.228 0.207 0.684 0.75 0.476 1.17 -0.591 0.6 0.324 0.489 0.554 0.162 1.73 -0.423 0.585 0.47 0.328 0.655 0.204 1.99 -1.03 0.654 0.116 0.935 0.358 0.0864 1.2 PRS_PLINK_0.000199526231496888 TRUE 292 Neurological disorders Both 59 341 5 mental disorders magenta 341, 59 85, 20 85, 17 85, 12 85, 10 -0.175 0.144 0.224 0.649 0.84 0.632 1.11 -0.106 0.372 0.776 0.11 0.9 0.434 1.85 -0.333 0.402 0.408 0.39 0.717 0.32 1.57 -0.632 0.422 0.134 0.873 0.531 0.225 1.19 PRS_PLINK_0.000199526231496888 FALSE 292.1 Aphasia/speech disturbance Both 11 138 5 mental disorders magenta 138, 11 34, 2 34, 2 34, 4 35, 3 0.21 0.306 0.494 0.307 1.23 0.669 2.42 0.0244 1.05 0.981 0.008 1.02 0.074 14 -0.121 0.842 0.886 0.053 0.886 0.139 5.82 0.394 1.04 0.704 0.152 1.48 0.163 19.2 PRS_PLINK_0.000199526231496888 TRUE 292.11 Aphasia Both 4 57 5 mental disorders magenta 57, 4 15, 0 14, 2 14, 1 14, 1 0.0654 0.6 0.913 0.039 1.07 0.231 6.12 2 1.65 0.225 0.647 7.4 0.366 83000 -0.578 1.68 0.731 0.136 0.561 0.000278 34 -0.277 1.47 0.85 0.07 0.758 0.0059 130 PRS_PLINK_0.000199526231496888 TRUE 292.12 Symbolic dysfunction Both 1 23 5 mental disorders magenta 23, 1 6, 1 6, 0 5, 0 6, 0 -0.127 0.841 0.88 0.056 0.88 0.105 21.5 0.129 2.25 0.954 0.02 1.14 0.008 107 -0.0595 1.92 0.975 0.011 0.942 0.0439 189 -0.138 2.71 0.959 0.018 0.871 0.00296 307 PRS_PLINK_0.000199526231496888 TRUE 292.2 Mild cognitive impairment Both 3 16 5 mental disorders magenta 16, 3 4, 1 4, 1 4, 1 4, 0 -0.668 0.664 0.314 0.503 0.513 0.0212 1.47 0.65 5.38 0.904 0.044 1.91 1.48 2.07 0.115 3.07 0.97 0.013 1.12 0.0127 138 -1.35 2.78 0.628 0.202 0.259 0.00195 11.6 PRS_PLINK_0.000199526231496888 TRUE 292.3 Memory loss Both 19 116 5 mental disorders magenta 116, 19 28, 7 29, 6 29, 3 29, 3 -0.271 0.246 0.27 0.569 0.763 0.467 1.24 -0.242 0.632 0.702 0.154 0.785 0.217 2.65 -0.872 0.694 0.209 0.679 0.418 0.0927 1.55 -0.524 0.704 0.457 0.34 0.592 0.129 2.28 PRS_PLINK_0.000199526231496888 TRUE 292.4 Altered mental status Both 21 141 5 mental disorders magenta 141, 21 35, 7 35, 10 35, 3 35, 1 -0.37 0.24 0.123 0.909 0.691 0.428 1.11 0.291 0.559 0.603 0.22 1.34 0.46 4.05 -0.0302 0.766 0.969 0.014 0.97 0.2 4.66 -0.918 0.884 0.299 0.524 0.399 0.0408 2.29 PRS_PLINK_0.000199526231496888 TRUE 292.5 Transient alteration of awareness Both 4 28 5 mental disorders magenta 28, 4 6, 1 7, 1 7, 1 7, 1 -0.111 0.719 0.877 0.057 0.895 0.192 6.91 -0.883 2.33 0.705 0.152 0.414 0.00422 65.5 0.606 1.85 0.743 0.129 1.83 0.1 637 3.2 4.35 0.462 0.336 24.6 0.0348 1.24e+08 PRS_PLINK_0.000199526231496888 TRUE 292.6 Hallucinations Both 4 20 5 mental disorders magenta 20, 4 5, 0 5, 3 5, 0 5, 1 0.0251 0.813 0.975 0.011 1.03 0.13 5.17 -0.456 2.9 0.875 0.058 0.634 0.000325 7180 1.14 2.3 0.619 0.208 3.14 0.0485 1620 PRS_PLINK_0.000199526231496888 TRUE 293 Symptoms involving head and neck Both 8 44 5 mental disorders magenta 44, 8 11, 2 11, 1 11, 3 11, 2 -0.166 0.363 0.646 0.189 0.847 0.406 1.66 -0.114 1.69 0.946 0.024 0.892 0.00259 24 0.392 1.13 0.728 0.138 1.48 0.169 17.6 -1.23 1.59 0.438 0.359 0.291 0.00785 4.13 PRS_PLINK_0.000199526231496888 TRUE 293.1 Swelling, mass, or lump in head and neck [Space-occupying lesion, intracranial NOS] Both 54 345 5 mental disorders magenta 345, 54 86, 13 86, 13 86, 12 86, 16 0.0382 0.148 0.797 0.099 1.04 0.776 1.4 0.0754 0.412 0.855 0.068 1.08 0.472 2.46 -0.118 0.429 0.784 0.106 0.889 0.375 2.09 0.143 0.415 0.731 0.136 1.15 0.507 2.64 PRS_PLINK_0.000199526231496888 FALSE 295 Schizophrenia and other psychotic disorders Both 7 39 5 mental disorders magenta 39, 7 10, 4 10, 0 9, 0 10, 3 -0.132 0.426 0.756 0.122 0.876 0.371 2 -1.47 1.48 0.318 0.498 0.229 0.00201 3.08 -0.708 2.15 0.742 0.13 0.493 7.09e-06 32.1 0.0768 1.16 0.947 0.024 1.08 0.093 31.1 PRS_PLINK_0.000199526231496888 TRUE 295.1 Schizophrenia Both 1 8 5 mental disorders magenta 8, 1 2, 0 2, 0 2, 0 2, 1 -0.381 3.15 0.904 0.044 0.683 0.00664 128 0.129 2050 1 0 1.14 0.523 1.27 PRS_PLINK_0.000199526231496888 TRUE 295.2 Paranoid disorders Both 0 4 5 mental disorders magenta 4, 0 1 1 1 1 PRS_PLINK_0.000199526231496888 TRUE 295.3 Psychosis Both 6 27 5 mental disorders magenta 27, 6 7, 4 7, 0 6, 0 7, 2 -0.598 0.626 0.339 0.469 0.55 0.00702 1.68 -1.17 1.6 0.466 0.331 0.311 0.00274 4.19 -1.35 2.64 0.61 0.215 0.26 0.000781 64.9 -0.717 1.44 0.618 0.209 0.488 0.00939 13.5 PRS_PLINK_0.000199526231496888 TRUE 296 Mood disorders Both 243 116 5 mental disorders magenta 116, 243 29, 56 29, 53 29, 65 29, 68 -0.0866 0.122 0.477 0.322 0.917 0.722 1.16 -0.155 0.361 0.669 0.175 0.857 0.424 1.72 -0.0458 0.353 0.897 0.047 0.955 0.48 1.88 -0.211 0.359 0.556 0.255 0.809 0.399 1.62 PRS_PLINK_0.000199526231496888 FALSE 296.1 Bipolar Both 27 89 5 mental disorders magenta 89, 27 23, 8 22, 8 22, 6 22, 5 -0.406 0.252 0.107 0.969 0.666 0.402 1.07 -0.0886 0.637 0.89 0.051 0.915 0.264 3.03 -0.399 0.665 0.549 0.26 0.671 0.184 2.28 -0.791 0.675 0.241 0.617 0.453 0.117 1.56 PRS_PLINK_0.000199526231496888 TRUE 296.2 Depression Both 239 116 5 mental disorders magenta 116, 239 29, 54 29, 52 29, 64 29, 68 -0.0736 0.122 0.546 0.262 0.929 0.731 1.18 -0.138 0.363 0.703 0.153 0.871 0.43 1.75 -0.0272 0.355 0.939 0.027 0.973 0.487 1.92 -0.173 0.36 0.632 0.199 0.841 0.414 1.68 PRS_PLINK_0.000199526231496888 FALSE 296.22 Major depressive disorder Both 219 116 5 mental disorders magenta 116, 219 29, 54 29, 45 29, 58 29, 61 -0.116 0.124 0.349 0.458 0.89 0.698 1.13 -0.232 0.367 0.527 0.278 0.793 0.388 1.6 -0.134 0.36 0.709 0.149 0.875 0.434 1.74 -0.36 0.372 0.333 0.477 0.697 0.334 1.42 PRS_PLINK_0.000199526231496888 FALSE 297 Suicidal ideation or attempt Both 17 78 5 mental disorders magenta 78, 17 20, 2 19, 6 19, 3 20, 6 0.337 0.341 0.324 0.49 1.4 0.728 2.85 0.651 0.935 0.487 0.313 1.92 0.311 14.7 0.331 1.02 0.745 0.128 1.39 0.184 13.5 0.965 0.964 0.317 0.499 2.62 0.45 23.6 PRS_PLINK_0.000199526231496888 TRUE 297.1 Suicidal ideation Both 10 62 5 mental disorders magenta 62, 10 16, 1 15, 4 15, 0 16, 5 0.442 0.445 0.321 0.494 1.56 0.65 4.29 0.639 0.992 0.52 0.284 1.89 0.268 17 -1.14 1.38 0.41 0.387 0.321 0.000183 5.59 1.23 1.16 0.292 0.535 3.41 0.479 53.6 PRS_PLINK_0.000199526231496888 TRUE 297.2 Suicide or self-inflicted injury Both 6 30 5 mental disorders magenta 30, 6 8, 2 7, 1 7, 0 8, 3 -0.147 0.6 0.806 0.094 0.863 0.245 3.4 -0.749 1.34 0.575 0.241 0.473 0.0318 4.71 -2.39 2.33 0.305 0.516 0.0912 2.87e-05 4.76 0.35 1.67 0.834 0.079 1.42 0.0743 1190 PRS_PLINK_0.000199526231496888 TRUE 300 Anxiety disorders Both 248 116 5 mental disorders magenta 116, 248 29, 60 29, 59 29, 63 29, 65 -0.139 0.121 0.253 0.597 0.871 0.686 1.1 -0.141 0.351 0.688 0.163 0.868 0.438 1.71 -0.133 0.346 0.702 0.154 0.876 0.446 1.7 -0.351 0.354 0.321 0.493 0.704 0.35 1.39 PRS_PLINK_0.000199526231496888 FALSE 300.1 Anxiety disorder Both 232 116 5 mental disorders magenta 116, 232 29, 57 29, 57 29, 59 29, 58 -0.161 0.123 0.189 0.724 0.851 0.668 1.08 -0.124 0.353 0.725 0.139 0.883 0.444 1.74 -0.149 0.35 0.671 0.174 0.862 0.435 1.68 -0.419 0.36 0.244 0.612 0.658 0.323 1.31 PRS_PLINK_0.000199526231496888 FALSE 300.11 Generalized anxiety disorder Both 129 115 5 mental disorders magenta 115, 129 29, 32 29, 27 28, 37 29, 32 -0.0945 0.136 0.489 0.311 0.91 0.696 1.18 -0.099 0.435 0.82 0.086 0.906 0.391 2.09 0.0176 0.418 0.966 0.015 1.02 0.452 2.26 -0.295 0.415 0.477 0.322 0.744 0.33 1.64 PRS_PLINK_0.000199526231496888 FALSE 300.12 Agorophobia, social phobia, and panic disorder Both 38 93 5 mental disorders magenta 93, 38 24, 10 23, 12 23, 8 23, 8 -0.199 0.206 0.334 0.476 0.819 0.547 1.21 0.19 0.576 0.742 0.13 1.21 0.408 3.58 0.133 0.589 0.822 0.085 1.14 0.373 3.53 -0.512 0.65 0.431 0.366 0.599 0.167 2.01 PRS_PLINK_0.000199526231496888 TRUE 300.13 Phobia Both 24 72 5 mental disorders magenta 72, 24 18, 6 18, 7 18, 5 18, 6 -0.12 0.244 0.624 0.205 0.887 0.548 1.41 0.0979 0.696 0.888 0.051 1.1 0.297 4.06 -0.166 0.765 0.828 0.082 0.847 0.196 3.56 -0.294 0.756 0.697 0.157 0.745 0.171 3.04 PRS_PLINK_0.000199526231496888 TRUE 300.3 Obsessive-compulsive disorders Both 5 33 5 mental disorders magenta 33, 5 9, 3 8, 0 8, 1 8, 1 -1.21 0.99 0.22 0.658 0.297 0.000148 2.22 -1.08 1.73 0.531 0.275 0.338 0.00397 28.5 -1.86 2.07 0.369 0.433 0.155 3.21e-05 17.3 -0.874 1.31 0.506 0.296 0.417 0.0118 5.54 PRS_PLINK_0.000199526231496888 TRUE 300.4 Dysthymic disorder Both 50 104 5 mental disorders magenta 104, 50 26, 14 26, 13 26, 12 26, 11 -0.23 0.199 0.248 0.606 0.794 0.536 1.16 0.0612 0.526 0.907 0.042 1.06 0.39 2.89 0.301 0.59 0.61 0.215 1.35 0.445 4.28 -0.565 0.6 0.346 0.46 0.568 0.173 1.74 PRS_PLINK_0.000199526231496888 TRUE 300.8 Acute reaction to stress Both 10 31 5 mental disorders magenta 31, 10 8, 4 8, 1 7, 5 8, 0 -0.308 0.401 0.443 0.354 0.735 0.327 1.53 -2.93 2.51 0.243 0.615 0.0533 6.23e-12 3.25 0.399 1.01 0.692 0.16 1.49 0.263 8.87 -1.63 1.84 0.374 0.427 0.195 0.000301 4.6 PRS_PLINK_0.000199526231496888 TRUE 300.9 Posttraumatic stress disorder Both 18 66 5 mental disorders magenta 66, 18 17, 5 16, 1 16, 7 17, 5 0.132 0.292 0.652 0.186 1.14 0.65 2.03 -1.02 1.16 0.383 0.417 0.362 0.00368 3.25 0.915 0.781 0.241 0.617 2.5 0.602 12.6 0.95 0.997 0.341 0.468 2.59 0.49 3.06 PRS_PLINK_0.000199526231496888 TRUE 301 Personality disorders Both 17 47 5 mental disorders magenta 47, 17 12, 4 12, 4 11, 4 12, 5 0.252 0.373 0.499 0.302 1.29 0.646 2.77 -0.452 0.998 0.651 0.187 0.637 0.0898 3.99 0.624 0.928 0.501 0.3 1.87 0.35 12.2 0.947 0.97 0.329 0.483 2.58 0.478 18.9 PRS_PLINK_0.000199526231496888 TRUE 301.2 Antisocial/borderline personality disorder Both 5 28 5 mental disorders magenta 28, 5 7, 4 7, 0 7, 1 7, 0 -0.0909 0.765 0.905 0.043 0.913 0.138 5.12 -1.15 1.79 0.52 0.284 0.316 0.00233 6.1 1.15 2.19 0.599 0.223 3.16 0.0386 90900 -0.405 1.81 0.823 0.085 0.667 0.00391 20.6 PRS_PLINK_0.000199526231496888 TRUE 302 Sexual and gender identity disorders Both 27 63 5 mental disorders magenta 63, 27 16, 4 16, 8 15, 8 16, 7 0.188 0.277 0.497 0.304 1.21 0.71 2.08 0.617 0.759 0.416 0.38 1.85 0.467 8.29 0.528 0.763 0.489 0.311 1.7 0.419 7.19 0.0119 0.841 0.989 0.005 1.01 0.212 4.99 PRS_PLINK_0.000199526231496888 TRUE 302.1 Decreased libido Both 11 19 5 mental disorders magenta 19, 11 5, 1 5, 4 4, 1 5, 5 0.285 0.517 0.581 0.236 1.33 0.526 3.58 3.17 2.77 0.252 0.599 23.9 0.472 3.11e+08 -0.998 4.23 0.814 0.09 0.369 2.28e-06 346 1.82 2.7 0.499 0.302 6.2 0.0619 22000 PRS_PLINK_0.000199526231496888 TRUE 303 Psychogenic and somatoform disorders Both 101 114 5 mental disorders magenta 114, 101 29, 25 28, 19 28, 25 29, 32 0.15 0.144 0.297 0.527 1.16 0.882 1.54 0.00617 0.463 0.989 0.005 1.01 0.415 2.45 0.249 0.458 0.586 0.232 1.28 0.54 3.1 0.317 0.443 0.475 0.324 1.37 0.588 3.28 PRS_PLINK_0.000199526231496888 FALSE 303.1 Dissociative disorder Both 2 15 5 mental disorders magenta 15, 2 4, 0 4, 0 3, 0 4, 2 0.373 0.739 0.614 0.212 1.45 0.357 14 1.49 2.29 0.515 0.288 4.46 0.136 2680 PRS_PLINK_0.000199526231496888 TRUE 303.3 Psychogenic disorder Both 96 114 5 mental disorders magenta 114, 96 29, 24 28, 18 28, 24 29, 30 0.162 0.147 0.27 0.569 1.18 0.888 1.57 0.055 0.473 0.907 0.042 1.06 0.429 2.63 0.285 0.467 0.541 0.267 1.33 0.552 3.27 0.329 0.46 0.475 0.323 1.39 0.575 3.44 PRS_PLINK_0.000199526231496888 FALSE 303.31 Gastrointestinal malfunction arising from mental factors Both 14 35 5 mental disorders magenta 35, 14 9, 5 9, 2 8, 2 9, 5 -0.206 0.383 0.59 0.229 0.813 0.373 1.66 -2.42 2.06 0.241 0.618 0.0891 4.46e-09 2.6 -0.966 1.19 0.418 0.379 0.381 0.031 3.16 -1.06 1.17 0.368 0.434 0.347 0.02 2.44 PRS_PLINK_0.000199526231496888 TRUE 303.4 Somatoform disorder Both 24 90 5 mental disorders magenta 90, 24 23, 6 22, 8 22, 3 23, 7 -0.122 0.23 0.594 0.226 0.885 0.562 1.38 0.192 0.69 0.78 0.108 1.21 0.318 4.76 -0.304 0.794 0.702 0.154 0.738 0.151 3.33 -0.505 0.716 0.481 0.318 0.603 0.147 2.29 PRS_PLINK_0.000199526231496888 TRUE 304 Adjustment reaction Both 75 116 5 mental disorders magenta 116, 75 29, 26 29, 14 29, 17 29, 18 -0.144 0.155 0.35 0.456 0.866 0.64 1.16 -0.557 0.484 0.25 0.601 0.573 0.223 1.42 -0.635 0.48 0.186 0.729 0.53 0.207 1.29 -0.359 0.451 0.427 0.37 0.699 0.291 1.64 PRS_PLINK_0.000199526231496888 FALSE 305.2 Eating disorder Both 27 81 5 mental disorders magenta 81, 27 21, 8 20, 7 20, 5 20, 7 -0.0774 0.238 0.746 0.128 0.926 0.581 1.46 -0.00908 0.646 0.989 0.005 0.991 0.291 3.33 -0.121 0.754 0.872 0.059 0.886 0.201 3.76 0.163 0.651 0.802 0.096 1.18 0.346 4.08 PRS_PLINK_0.000199526231496888 TRUE 306 Other mental disorder Both 67 98 5 mental disorders magenta 98, 67 25, 19 24, 22 24, 11 25, 15 -0.228 0.178 0.201 0.696 0.796 0.562 1.12 0.343 0.471 0.466 0.331 1.41 0.58 3.47 -0.52 0.555 0.349 0.457 0.595 0.197 1.69 -0.337 0.498 0.498 0.303 0.714 0.274 1.81 PRS_PLINK_0.000199526231496888 FALSE 306.1 Mental disorders durring/after pregnancy Female 86 65 5 mental disorders magenta 65, 86 17, 23 16, 26 16, 23 16, 14 -0.24 0.197 0.223 0.652 0.787 0.536 1.14 0.311 0.485 0.521 0.283 1.37 0.548 3.45 0.0689 0.514 0.893 0.049 1.07 0.408 2.85 -0.602 0.556 0.279 0.555 0.548 0.186 1.54 PRS_PLINK_0.000199526231496888 FALSE 306.9 Tension headache Both 33 69 5 mental disorders magenta 69, 33 18, 11 17, 13 17, 2 17, 7 -0.344 0.248 0.165 0.782 0.709 0.431 1.13 0.817 0.693 0.239 0.622 2.26 0.653 8.73 -1.37 0.8 0.0867 1.062 0.254 0.0446 1.04 -0.851 0.73 0.244 0.613 0.427 0.0963 1.6 PRS_PLINK_0.000199526231496888 TRUE 312 Conduct disorders Both 1 18 5 mental disorders magenta 18, 1 5, 1 4, 0 4, 0 5, 0 -0.263 0.766 0.732 0.136 0.769 0.0873 4.73 -0.568 3.21 0.859 0.066 0.567 0.00202 68.5 0.194 2500000 1 0 1.21 0.263 3.02 -0.701 2.95 0.812 0.09 0.496 2.51e-05 54.1 PRS_PLINK_0.000199526231496888 TRUE 312.3 Impulse control disorder Both 0 11 5 mental disorders magenta 11, 0 3 3 2 3 PRS_PLINK_0.000199526231496888 TRUE 313 Pervasive developmental disorders Both 26 192 5 mental disorders magenta 192, 26 47, 8 48, 8 48, 7 48, 3 -0.35 0.217 0.107 0.972 0.705 0.456 1.08 -0.17 0.545 0.755 0.122 0.844 0.279 2.49 -0.242 0.556 0.664 0.178 0.785 0.259 2.31 -0.982 0.745 0.187 0.727 0.374 0.0651 1.58 PRS_PLINK_0.000199526231496888 TRUE 313.1 Attention deficit hyperactivity disorder Both 26 179 5 mental disorders magenta 179, 26 44, 8 45, 10 44, 5 45, 3 -0.375 0.22 0.0884 1.054 0.687 0.442 1.06 -0.0301 0.537 0.955 0.02 0.97 0.336 2.78 -0.48 0.586 0.413 0.384 0.619 0.184 1.92 -0.985 0.745 0.186 0.73 0.374 0.0655 1.56 PRS_PLINK_0.000199526231496888 TRUE 313.2 Tics and stuttering Both 0 15 5 mental disorders magenta 15, 0 4 4 3 4 PRS_PLINK_0.000199526231496888 TRUE 313.3 Autism Both 1 8 5 mental disorders magenta 8, 1 2, 1 2, 0 2, 0 2, 0 0.838 8.97 0.926 0.034 2.31 2.19 2.44 0.000691 54.3 1 0 1 0.889 1.22 -0.4 1110 1 0 0.671 0.00199 463 -0.299 33.8 0.993 0.003 0.742 0.0562 3.47 PRS_PLINK_0.000199526231496888 TRUE 315 Develomental delays and disorders Both 5 65 5 mental disorders magenta 65, 5 17, 2 16, 0 16, 2 16, 1 -0.247 0.44 0.574 0.241 0.781 0.282 2.01 -1.69 1.3 0.193 0.714 0.185 0.000274 2.25 -0.159 0.966 0.869 0.061 0.853 0.105 5.81 -1.34 1.33 0.316 0.501 0.263 3.8e-05 4.11 PRS_PLINK_0.000199526231496888 TRUE 315.1 Learning disorder Both 0 10 5 mental disorders magenta 10, 0 3 2 2 3 PRS_PLINK_0.000199526231496888 TRUE 315.2 Speech and language disorder Both 1 26 5 mental disorders magenta 26, 1 6, 0 6, 0 6, 0 7, 1 0.00751 0.652 0.991 0.004 1.01 0.138 12.6 -0.84 2.59 0.745 0.128 0.432 0.00014 650 PRS_PLINK_0.000199526231496888 TRUE 316 Substance addiction and disorders Both 37 317 5 mental disorders magenta 317, 37 79, 12 79, 5 79, 10 79, 10 0.0266 0.172 0.877 0.057 1.03 0.728 1.45 -0.823 0.581 0.157 0.805 0.439 0.126 1.35 -0.0507 0.458 0.912 0.04 0.951 0.379 2.38 -0.0316 0.459 0.945 0.025 0.969 0.385 2.43 PRS_PLINK_0.000199526231496888 TRUE 316.1 Polyneuropathy due to drugs Both 6 62 5 mental disorders magenta 62, 6 16, 2 15, 1 15, 3 16, 0 -0.385 0.413 0.351 0.454 0.681 0.256 1.58 0.621 1.35 0.644 0.191 1.86 0.119 549 -0.0556 1.02 0.957 0.019 0.946 0.0994 7.44 -0.839 1.38 0.545 0.264 0.432 0.00103 14.4 PRS_PLINK_0.000199526231496888 TRUE 317 Alcohol-related disorders Both 24 169 5 mental disorders magenta 169, 24 42, 5 42, 3 42, 7 42, 9 0.357 0.23 0.121 0.917 1.43 0.907 2.32 -0.395 0.715 0.581 0.236 0.674 0.137 2.86 0.144 0.705 0.838 0.077 1.16 0.261 5.14 0.468 0.608 0.441 0.356 1.6 0.482 5.64 PRS_PLINK_0.000199526231496888 TRUE 317.1 Alcoholism Both 15 134 5 mental disorders magenta 134, 15 34, 3 33, 2 33, 6 34, 4 0.282 0.277 0.309 0.51 1.33 0.756 2.4 0.34 0.898 0.705 0.152 1.41 0.216 10.2 1.14 0.862 0.188 0.726 3.11 0.58 23.7 0.87 0.89 0.328 0.484 2.39 0.407 23.1 PRS_PLINK_0.000199526231496888 TRUE 317.11 Alcoholic liver damage Both 2 22 5 mental disorders magenta 22, 2 6, 1 5, 0 5, 1 6, 0 0.321 0.849 0.705 0.152 1.38 0.101 84.9 -0.51 2.76 0.853 0.069 0.6 0.000669 1830 0.0809 1.81 0.964 0.016 1.08 0.00366 57.3 0.896 4.58 0.845 0.073 2.45 0.00076 3450 PRS_PLINK_0.000199526231496888 TRUE 318 Tobacco use disorder Both 84 336 5 mental disorders magenta 336, 84 83, 20 84, 20 84, 17 84, 27 0.0887 0.127 0.483 0.316 1.09 0.854 1.4 -0.14 0.363 0.699 0.156 0.869 0.426 1.76 -0.19 0.369 0.607 0.216 0.827 0.399 1.7 0.376 0.345 0.276 0.559 1.46 0.746 2.88 PRS_PLINK_0.000199526231496888 FALSE 320 Meningitis Both 6 36 6 neurological darkblue 36, 6 9, 2 9, 2 9, 1 9, 1 1.11 0.921 0.228 0.642 3.03 0.394 147000 1.57 1.67 0.348 0.458 4.8 0.253 1010 -0.339 1.74 0.845 0.073 0.712 0.000747 79.4 0.0652 1.97 0.974 0.012 1.07 0.00289 242 PRS_PLINK_0.000199526231496888 TRUE 323 Encephalitis Both 6 19 6 neurological darkblue 19, 6 5, 5 5, 1 4, 0 5, 0 0.294 1.17 0.802 0.096 1.34 0.00279 39.8 -0.5 1.84 0.786 0.104 0.607 0.00119 267 0.437 2.58 0.865 0.063 1.55 4.22e-07 955 -0.42 2.2 0.849 0.071 0.657 0.00136 152 PRS_PLINK_0.000199526231496888 TRUE 323.8 Encephalitis, non-infectious Both 5 13 6 neurological darkblue 13, 5 4, 4 3, 1 3, 0 3, 0 -0.307 1.09 0.779 0.109 0.736 0.012 14.5 -0.348 2.69 0.897 0.047 0.706 0.00603 76.9 0.214 2.64 0.935 0.029 1.24 3.02e-05 237 -2.72 7.17 0.705 0.152 0.0661 2.07e-07 46900 PRS_PLINK_0.000199526231496888 TRUE 324 Other CNS infection and poliomyelitis Both 2 15 6 neurological darkblue 15, 2 4, 0 4, 2 3, 0 4, 0 -0.422 0.764 0.581 0.236 0.656 0.0415 2.11 -1.32 3.32 0.692 0.16 0.268 0.000192 25.8 PRS_PLINK_0.000199526231496888 TRUE 325 Phlebitis and thrombophlebitis of intracranial venous sinuses Both 0 6 6 neurological darkblue 6, 0 2 1 1 2 PRS_PLINK_0.000199526231496888 TRUE 327 Sleep disorders Both 190 262 6 neurological darkblue 262, 190 66, 49 65, 45 65, 45 66, 50 -0.0763 0.104 0.464 0.334 0.927 0.756 1.13 -0.0751 0.294 0.798 0.098 0.928 0.525 1.63 -0.166 0.295 0.573 0.242 0.847 0.478 1.49 -0.0244 0.288 0.933 0.03 0.976 0.561 1.7 PRS_PLINK_0.000199526231496888 FALSE 327.1 Hypersomnia Both 50 162 6 neurological darkblue 162, 50 41, 17 40, 11 40, 13 41, 8 -0.46 0.194 0.0176 1.755 0.631 0.43 0.912 -0.833 0.526 0.114 0.945 0.435 0.152 1.15 -0.309 0.47 0.511 0.291 0.734 0.293 1.79 -0.787 0.528 0.136 0.867 0.455 0.154 1.23 PRS_PLINK_0.000199526231496888 TRUE 327.3 Sleep apnea Both 135 262 6 neurological darkblue 262, 135 66, 38 65, 33 65, 30 66, 33 -0.126 0.117 0.281 0.551 0.882 0.702 1.11 -0.0533 0.317 0.866 0.062 0.948 0.514 1.74 -0.274 0.332 0.41 0.387 0.761 0.398 1.44 -0.183 0.321 0.569 0.245 0.833 0.449 1.54 PRS_PLINK_0.000199526231496888 FALSE 327.31 Central/nonobstroctive sleep apnea Both 7 22 6 neurological darkblue 22, 7 6, 3 5, 1 5, 2 6, 1 -0.433 0.465 0.353 0.453 0.649 0.209 1.53 -1.49 1.92 0.437 0.36 0.225 0.0014 4.17 -0.166 1.59 0.917 0.038 0.847 0.0588 11.9 -0.204 1.67 0.902 0.045 0.815 0.0279 0.952 PRS_PLINK_0.000199526231496888 TRUE 327.32 Obstructive sleep apnea Both 124 255 6 neurological darkblue 255, 124 64, 38 64, 35 63, 26 64, 24 -0.221 0.121 0.0684 1.165 0.802 0.633 1.01 -0.0164 0.313 0.958 0.019 0.984 0.538 1.8 -0.354 0.34 0.297 0.527 0.702 0.362 1.34 -0.492 0.342 0.15 0.823 0.611 0.314 1.17 PRS_PLINK_0.000199526231496888 FALSE 327.4 Insomnia Both 95 262 6 neurological darkblue 262, 95 66, 26 65, 20 65, 28 66, 21 -0.0764 0.137 0.578 0.238 0.926 0.709 1.21 -0.13 0.381 0.733 0.135 0.878 0.417 1.84 0.188 0.365 0.606 0.218 1.21 0.6 2.45 -0.344 0.383 0.369 0.433 0.709 0.334 1.48 PRS_PLINK_0.000199526231496888 FALSE 327.41 Organic or persistent insomnia Both 22 93 6 neurological darkblue 93, 22 24, 7 23, 5 23, 3 23, 7 -0.198 0.258 0.443 0.354 0.82 0.491 1.34 -0.543 0.756 0.473 0.325 0.581 0.12 2.34 -1.4 0.918 0.128 0.891 0.248 0.0288 1.32 0.117 0.68 0.864 0.064 1.12 0.307 4.09 PRS_PLINK_0.000199526231496888 TRUE 327.5 Parasomnia Both 8 42 6 neurological darkblue 42, 8 11, 5 10, 0 10, 2 11, 1 -1.07 0.633 0.0901 1.045 0.342 0.0319 1.09 -3.06 2.02 0.13 0.886 0.0469 3.71e-05 1.16 -2.6 1.52 0.0861 1.065 0.0742 0.00108 0.895 -4.61 2.22 0.0376 1.424 0.00999 5.68e-06 0.397 PRS_PLINK_0.000199526231496888 TRUE 327.6 Circadian rhythm sleep disorder Both 5 20 6 neurological darkblue 20, 5 5, 4 5, 1 5, 0 5, 0 -0.746 0.704 0.289 0.538 0.474 0.104 1.81 0.461 1.62 0.775 0.11 1.59 0.102 38.1 -1.43 2.22 0.518 0.285 0.239 0.00209 27.7 -1 2.12 0.637 0.196 0.367 0.00139 8.38 PRS_PLINK_0.000199526231496888 TRUE 327.7 Sleep related movement disorders Both 34 120 6 neurological darkblue 120, 34 30, 11 30, 4 30, 10 30, 9 -0.215 0.241 0.372 0.43 0.806 0.501 1.28 -1.81 0.836 0.0303 1.518 0.163 0.0231 0.732 -0.525 0.573 0.36 0.444 0.591 0.192 1.77 -0.447 0.632 0.479 0.319 0.64 0.178 2.15 PRS_PLINK_0.000199526231496888 TRUE 327.71 Restless legs syndrome Both 31 111 6 neurological darkblue 111, 31 28, 10 28, 3 27, 10 28, 8 -0.187 0.253 0.459 0.338 0.829 0.5 1.35 -1.7 0.869 0.0508 1.294 0.183 0.0252 0.871 -0.401 0.596 0.501 0.3 0.67 0.21 2.11 -0.414 0.65 0.524 0.281 0.661 0.177 2.3 PRS_PLINK_0.000199526231496888 TRUE 327.72 Sleep related leg cramps Both 1 3 6 neurological darkblue 3, 1 1, 0 1, 1 1, 0 1, 0 -0.228 37700 1 0 0.796 0.0671 2.16 -0.00819 57.4 1 0 0.992 0.827 1.17 PRS_PLINK_0.000199526231496888 TRUE 331 Other cerebral degenerations Both 5 38 6 neurological darkblue 38, 5 10, 2 9, 1 9, 0 10, 2 -0.22 0.58 0.704 0.152 0.802 0.169 4.67 -0.347 1.5 0.817 0.088 0.707 0.00574 21.3 -1.03 2.77 0.709 0.149 0.357 2.14e-06 3200 0.412 1.6 0.796 0.099 1.51 0.0143 1100 PRS_PLINK_0.000199526231496888 TRUE 331.1 Hydrocephalus Both 2 18 6 neurological darkblue 18, 2 5, 1 4, 1 4, 0 5, 0 -0.0802 0.77 0.917 0.038 0.923 0.191 65.5 0.0636 833 1 0 1.07 0.887 1.22 -0.186 4.94 0.97 0.013 0.831 0.78 1.01 -0.479 2.21 0.828 0.082 0.619 0.00303 23.8 PRS_PLINK_0.000199526231496888 TRUE 331.9 Cerebral degeneration, unspecified Both 3 17 6 neurological darkblue 17, 3 5, 1 4, 0 4, 0 4, 2 -0.0873 0.694 0.9 0.046 0.916 0.116 65.1 0.723 4.78 0.88 0.056 2.06 6.19e-06 12900 0.274 8.49 0.974 0.011 1.32 1.25 1.37 -0.413 5.76 0.943 0.026 0.661 3.21e-05 2090 PRS_PLINK_0.000199526231496888 TRUE 332 Parkinson's disease Both 2 13 6 neurological darkblue 13, 2 4, 0 3, 0 3, 0 3, 2 0.614 0.844 0.467 0.331 1.85 0.38 51.6 1.03 2740000 1 0 2.81 0.648 13.5 PRS_PLINK_0.000199526231496888 TRUE 333 Extrapyramidal disease and abnormal movement disorders Both 44 221 6 neurological darkblue 221, 44 55, 11 55, 10 55, 15 55, 8 -0.0789 0.177 0.656 0.183 0.924 0.651 1.31 -0.234 0.485 0.629 0.201 0.791 0.299 2.04 0.223 0.477 0.64 0.194 1.25 0.49 3.24 -0.693 0.559 0.216 0.666 0.5 0.153 1.46 PRS_PLINK_0.000199526231496888 TRUE 333.1 Essential tremor Both 10 41 6 neurological darkblue 41, 10 11, 0 10, 8 10, 2 10, 0 -0.0814 0.437 0.852 0.069 0.922 0.378 2.14 2.93 1.49 0.0498 1.303 18.7 2.12 25.3 0.434 1.68 0.796 0.099 1.54 0.0274 87.7 PRS_PLINK_0.000199526231496888 TRUE 333.2 Myoclonus Both 1 18 6 neurological darkblue 18, 1 5, 0 4, 1 4, 0 5, 0 -0.104 0.74 0.888 0.051 0.901 0.0216 7.37 0.187 7.08 0.979 0.009 1.21 1.18 1.23 PRS_PLINK_0.000199526231496888 TRUE 333.4 Torsion dystonia Both 4 30 6 neurological darkblue 30, 4 8, 0 7, 0 7, 1 8, 3 0.567 0.814 0.486 0.313 1.76 0.119 55.9 0.245 3.16 0.938 0.028 1.28 0.000876 9380 0.347 2.07 0.867 0.062 1.42 9.39e-05 687 PRS_PLINK_0.000199526231496888 TRUE 333.8 Other degenerative diseases of the basal ganglia Both 3 4 6 neurological darkblue 4, 3 1, 3 1, 0 1, 0 1, 0 0.000478 9.12 1 0 1 0.835 1.29 -0.25 6690 1 0 0.779 0.225 1.9 -0.0148 398 1 0 0.985 0.848 1.19 -0.036 655 1 0 0.965 0.772 1.15 PRS_PLINK_0.000199526231496888 TRUE 334 Degenerative disease of the spinal cord Both 14 74 6 neurological darkblue 74, 14 19, 5 18, 7 18, 1 19, 1 -0.567 0.36 0.115 0.938 0.567 0.265 1.12 0.577 0.85 0.497 0.303 1.78 0.364 9.91 -2.17 1.42 0.127 0.896 0.114 0.000206 1.21 -0.909 1.09 0.406 0.391 0.403 0.0279 3.02 PRS_PLINK_0.000199526231496888 TRUE 334.1 Spinocerebellar disease Both 1 6 6 neurological darkblue 6, 1 2, 0 1, 1 1, 0 2, 0 0.0217 1160 1 0 1.02 0.772 1.12 -0.00578 594 1 0 0.994 0.923 1.07 PRS_PLINK_0.000199526231496888 TRUE 334.2 Anterior horn cell disease Both 1 9 6 neurological darkblue 9, 1 3, 1 2, 0 2, 0 2, 0 0.315 3.55 0.929 0.032 1.37 1.34 1.4 -0.00581 827 1 0 0.994 0.774 1.83 -0.141 1880 1 0 0.869 0.72 1.77 -0.0388 36700000 1 0 0.962 0.245 3.25 PRS_PLINK_0.000199526231496888 TRUE 334.21 Amyotrophic Lateral Sclerosis Both 1 4 6 neurological darkblue 4, 1 1, 1 1, 0 1, 0 1, 0 0.000113 147 1 0 1 0.837 1.13 -0.00849 92.2 1 0 0.992 0.788 1.13 -0.0394 58.9 0.999 0 0.961 0.867 2.24 -0.052 29.1 0.999 0.001 0.949 0.913 1.56 PRS_PLINK_0.000199526231496888 TRUE 335 Multiple sclerosis Both 6 48 6 neurological darkblue 48, 6 12, 0 12, 2 12, 1 12, 3 0.408 0.536 0.447 0.35 1.5 0.525 5.12 0.583 1.48 0.693 0.159 1.79 0.0103 557 1.08 1.5 0.472 0.326 2.94 0.165 1330 2.25 1.71 0.188 0.725 9.53 0.476 7090 PRS_PLINK_0.000199526231496888 TRUE 337 Disorders of the autonomic nervous system Both 8 67 6 neurological darkblue 67, 8 17, 3 17, 4 16, 0 17, 1 -0.289 0.38 0.446 0.351 0.749 0.334 1.59 -0.501 0.962 0.603 0.22 0.606 0.081 4.02 -2.49 1.83 0.174 0.759 0.083 1.46e-05 1.87 -0.643 1.17 0.584 0.234 0.526 0.0322 5.44 PRS_PLINK_0.000199526231496888 TRUE 337.1 Peripheral autonomic neuropathy Both 3 22 6 neurological darkblue 22, 3 6, 2 5, 0 5, 0 6, 1 -0.2 0.867 0.817 0.088 0.818 0.0362 5.41 -1.46 2.1 0.484 0.315 0.231 0.00162 4.08 -1.77 4.19 0.673 0.172 0.171 1.3e-05 126 -0.869 2.39 0.716 0.145 0.419 0.00135 36.3 PRS_PLINK_0.000199526231496888 TRUE 338 Pain Both 230 223 6 neurological darkblue 223, 230 55, 59 56, 47 55, 62 56, 62 0.091 0.0995 0.36 0.443 1.1 0.904 1.33 -0.136 0.295 0.645 0.191 0.873 0.493 1.54 0.101 0.281 0.719 0.143 1.11 0.644 1.91 0.082 0.288 0.776 0.11 1.09 0.624 1.89 PRS_PLINK_0.000199526231496888 FALSE 338.1 Acute pain Both 171 223 6 neurological darkblue 223, 171 55, 43 56, 34 55, 47 56, 47 0.0994 0.108 0.359 0.445 1.1 0.896 1.36 -0.146 0.33 0.657 0.182 0.864 0.455 1.63 0.129 0.306 0.672 0.173 1.14 0.633 2.05 0.168 0.314 0.593 0.227 1.18 0.647 2.17 PRS_PLINK_0.000199526231496888 FALSE 338.2 Chronic pain Both 147 223 6 neurological darkblue 223, 147 55, 41 56, 32 55, 35 56, 39 0.047 0.112 0.675 0.17 1.05 0.844 1.3 -0.201 0.334 0.546 0.263 0.818 0.427 1.55 -0.192 0.33 0.562 0.25 0.826 0.437 1.55 -0.0341 0.325 0.916 0.038 0.966 0.519 1.8 PRS_PLINK_0.000199526231496888 FALSE 339 Other headache syndromes Both 206 213 6 neurological darkblue 213, 206 54, 58 53, 44 53, 40 53, 63 -0.0298 0.105 0.777 0.11 0.971 0.792 1.19 -0.321 0.295 0.276 0.559 0.725 0.41 1.27 -0.539 0.317 0.0885 1.053 0.583 0.314 1.07 -0.0415 0.296 0.889 0.051 0.959 0.541 1.7 PRS_PLINK_0.000199526231496888 FALSE 340 Migraine Both 152 204 6 neurological darkblue 204, 152 51, 44 51, 41 51, 28 51, 38 -0.219 0.123 0.0738 1.132 0.803 0.632 1.02 -0.132 0.315 0.675 0.171 0.876 0.477 1.6 -0.566 0.35 0.106 0.976 0.568 0.287 1.11 -0.291 0.335 0.385 0.415 0.747 0.39 1.42 PRS_PLINK_0.000199526231496888 FALSE 340.1 Migrain with aura Both 83 183 6 neurological darkblue 183, 83 46, 22 46, 22 45, 15 46, 23 -0.174 0.151 0.249 0.603 0.84 0.625 1.12 -0.0311 0.384 0.936 0.029 0.969 0.465 2.02 -0.355 0.413 0.39 0.409 0.701 0.314 1.54 -0.0496 0.399 0.901 0.045 0.952 0.442 2.05 PRS_PLINK_0.000199526231496888 FALSE 341 Other demyelinating diseases of central nervous system Both 1 11 6 neurological darkblue 11, 1 3, 0 3, 0 2, 1 3, 0 0.00661 1.1 0.995 0.002 1.01 0.0201 7.95 -0.0413 505 1 0 0.96 0.939 1.14 PRS_PLINK_0.000199526231496888 TRUE 342 Hemiplegia Both 5 31 6 neurological darkblue 31, 5 8, 1 8, 2 7, 1 8, 1 -0.431 0.596 0.469 0.328 0.65 0.143 2.67 -0.691 2.03 0.734 0.134 0.501 0.000275 57.5 0.36 1.62 0.824 0.084 1.43 0.0344 15800 -0.922 2.54 0.717 0.144 0.398 1.59e-05 177 PRS_PLINK_0.000199526231496888 TRUE 343 Infantile cerebral palsy Both 2 11 6 neurological darkblue 11, 2 3, 1 3, 1 2, 0 3, 0 -0.795 1.08 0.464 0.334 0.451 0.0291 13.5 -0.0295 2.44 0.99 0.004 0.971 0.012 39.2 0.133 2900 1 0 1.14 0.704 3.1 -4.9e-12 16.1 1 0 1 0.394 3.36 PRS_PLINK_0.000199526231496888 TRUE 344 Other paralytic syndromes Both 10 53 6 neurological darkblue 53, 10 14, 3 13, 4 13, 3 13, 0 -0.953 0.613 0.12 0.922 0.385 0.053 1.37 -2.02 1.78 0.258 0.588 0.133 0.00295 2.78 -0.453 1.25 0.717 0.145 0.636 0.0205 6.98 -1.93 1.74 0.265 0.576 0.144 3.64e-07 2.93 PRS_PLINK_0.000199526231496888 TRUE 345 Epilepsy, recurrent seizures, convulsions Both 25 267 6 neurological darkblue 267, 25 66, 5 67, 6 66, 6 67, 8 0.121 0.207 0.559 0.253 1.13 0.742 1.73 0.12 0.596 0.84 0.076 1.13 0.334 3.92 -0.112 0.63 0.859 0.066 0.894 0.245 3.3 0.303 0.617 0.624 0.205 1.35 0.388 5.01 PRS_PLINK_0.000199526231496888 TRUE 345.1 Epilepsy Both 9 89 6 neurological darkblue 89, 9 23, 1 22, 3 22, 4 22, 1 0.0693 0.351 0.843 0.074 1.07 0.506 2.29 1.37 1.22 0.262 0.582 3.92 0.385 2250 1.05 1.01 0.301 0.521 2.85 0.417 34.5 1.03 1.59 0.519 0.285 2.79 0.0158 2720000 PRS_PLINK_0.000199526231496888 TRUE 345.11 Generalized convulsive epilepsy Both 1 36 6 neurological darkblue 36, 1 9, 0 9, 1 9, 0 9, 0 -0.105 0.674 0.876 0.057 0.9 0.0368 10.2 0.963 1.87 0.607 0.217 2.62 0.0261 1050 PRS_PLINK_0.000199526231496888 TRUE 345.12 Partial epilepsy Both 9 60 6 neurological darkblue 60, 9 15, 1 15, 3 15, 3 15, 2 0.316 0.403 0.434 0.363 1.37 0.604 3.18 0.571 1.17 0.627 0.203 1.77 0.167 198 0.466 1.25 0.708 0.15 1.59 0.0733 113 1.02 1.68 0.543 0.266 2.79 0.0911 611000 PRS_PLINK_0.000199526231496888 TRUE 345.3 Convulsions Both 23 256 6 neurological darkblue 256, 23 63, 5 64, 5 64, 5 64, 8 0.16 0.211 0.45 0.347 1.17 0.764 1.82 -0.102 0.616 0.869 0.061 0.903 0.248 3.21 -0.193 0.636 0.762 0.118 0.825 0.215 3.09 0.356 0.623 0.568 0.246 1.43 0.408 5.4 PRS_PLINK_0.000199526231496888 TRUE 346 Abnormal findings on study of brain and/or nervous system Both 4 10 6 neurological darkblue 10, 4 3, 2 2, 1 2, 1 3, 0 0.798 2.11 0.706 0.151 2.22 0.00869 99.6 -0.1 2270 1 0 0.904 0.243 1.92 -0.223 7950 1 0 0.8 0.113 7.91 0.0149 1840 1 0 1.01 0.608 1.78 PRS_PLINK_0.000199526231496888 TRUE 346.1 Nonspecific abnormal findings on radiological and other examination of skull and head Both 17 106 6 neurological darkblue 106, 17 27, 7 26, 5 26, 1 27, 4 -0.0688 0.278 0.804 0.095 0.934 0.532 1.62 0.164 0.698 0.814 0.089 1.18 0.305 4.8 -1.64 1.08 0.127 0.896 0.194 0.00806 1.42 0.0261 0.756 0.972 0.012 1.03 0.225 4.78 PRS_PLINK_0.000199526231496888 TRUE 346.2 Nonspecific abnormal results of function study of brain and central nervous system Both 2 7 6 neurological darkblue 7, 2 2, 1 2, 0 1, 1 2, 0 1.11 2660 1 0 3.03 0.0578 197 -0.038 2510 1 0 0.963 3.13e-08 11600000 -2.64 1.42e+08 1 0 0.071 2.95e-11 0.182 2.53 2270 0.999 0 12.6 0.303 199 PRS_PLINK_0.000199526231496888 TRUE 346.3 Nonspecific abnormal findings in cerebrospinal fluid Both 1 11 6 neurological darkblue 11, 1 3, 1 3, 0 2, 0 3, 0 -0.0277 0.868 0.975 0.011 0.973 0.182 7.59 -0.0162 54 1 0 0.984 0.869 1.09 -0.0649 798 1 0 0.937 0.118 1.9 -0.0362 50.8 0.999 0 0.964 0.723 1.38 PRS_PLINK_0.000199526231496888 TRUE 347 Cataplexy and narcolepsy Both 5 16 6 neurological darkblue 16, 5 4, 0 4, 2 4, 2 4, 1 0.235 1.09 0.829 0.082 1.27 0.176 52.4 -0.355 2.74 0.897 0.047 0.701 0.557 0.94 0.195 16.2 0.99 0.004 1.21 6.52e-07 2100000 2.01 23.1 0.931 0.031 7.46 9.22e-07 67300000 PRS_PLINK_0.000199526231496888 TRUE 348 Other conditions of brain Both 19 159 6 neurological darkblue 159, 19 39, 5 40, 5 39, 5 40, 4 -0.0129 0.263 0.961 0.017 0.987 0.585 1.69 0.656 0.743 0.377 0.424 1.93 0.468 9.52 0.0298 0.722 0.967 0.015 1.03 0.238 4.32 -0.0689 0.732 0.925 0.034 0.933 0.207 4.14 PRS_PLINK_0.000199526231496888 TRUE 348.2 Cerebral edema and compression of brain Both 8 91 6 neurological darkblue 91, 8 23, 3 23, 0 22, 3 23, 2 0.364 0.472 0.44 0.357 1.44 0.58 4.16 -0.968 1.2 0.418 0.379 0.38 0.00166 4.48 0.0543 0.997 0.957 0.019 1.06 0.098 9.45 0.155 0.956 0.871 0.06 1.17 0.173 9.01 PRS_PLINK_0.000199526231496888 TRUE 348.4 Cerebral cysts Both 6 24 6 neurological darkblue 24, 6 6, 2 6, 2 6, 0 6, 2 -0.0823 14.2 0.995 0.002 0.921 0.862 1.2 -1.3 1.74 0.455 0.342 0.273 0.00135 3.28 -1.7 1.85 0.36 0.444 0.184 1.67e-05 4.6 -1 19 0.958 0.019 0.368 0.373 0.437 PRS_PLINK_0.000199526231496888 TRUE 348.7 Coma Both 0 13 6 neurological darkblue 13, 0 4 3 3 3 PRS_PLINK_0.000199526231496888 TRUE 348.8 Encephalopathy, not elsewhere classified Both 6 53 6 neurological darkblue 53, 6 14, 2 13, 3 13, 0 13, 1 -0.169 0.457 0.711 0.148 0.844 0.291 2.14 1.04 1.28 0.417 0.38 2.84 0.165 73.3 -0.79 1.52 0.604 0.219 0.454 0.0169 20.4 1.52 1.56 0.328 0.484 4.59 0.266 755 PRS_PLINK_0.000199526231496888 TRUE 348.9 Other conditions of brain, NOS Both 29 189 6 neurological darkblue 189, 29 48, 7 47, 8 47, 4 47, 10 0.258 0.213 0.227 0.645 1.29 0.859 1.98 0.474 0.624 0.448 0.349 1.61 0.491 5.68 -0.146 0.727 0.841 0.075 0.864 0.182 3.92 0.778 0.619 0.209 0.68 2.18 0.675 8.06 PRS_PLINK_0.000199526231496888 TRUE 349 Other and unspecified disorders of the nervous system Both 17 76 6 neurological darkblue 76, 17 19, 3 19, 6 19, 5 19, 3 0.057 0.373 0.879 0.056 1.06 0.498 2.26 1.03 0.959 0.285 0.546 2.79 0.495 21.4 0.329 0.938 0.726 0.139 1.39 0.217 9.44 0.475 1.05 0.652 0.186 1.61 0.217 20.7 PRS_PLINK_0.000199526231496888 TRUE 350 Abnormal movement Both 89 348 6 neurological darkblue 348, 89 86, 26 87, 24 87, 20 87, 19 -0.0484 0.134 0.719 0.143 0.953 0.732 1.24 -0.128 0.353 0.716 0.145 0.88 0.441 1.75 -0.394 0.395 0.318 0.497 0.675 0.307 1.44 -0.131 0.381 0.731 0.136 0.877 0.417 1.83 PRS_PLINK_0.000199526231496888 FALSE 350.1 Abnormal involuntary movements Both 57 233 6 neurological darkblue 233, 57 58, 18 58, 13 58, 18 58, 8 -0.104 0.159 0.511 0.291 0.901 0.658 1.23 -0.3 0.426 0.481 0.317 0.741 0.321 1.68 -0.242 0.446 0.588 0.231 0.785 0.324 1.86 -0.527 0.483 0.275 0.561 0.59 0.221 1.49 PRS_PLINK_0.000199526231496888 FALSE 350.2 Abnormality of gait Both 50 187 6 neurological darkblue 187, 50 47, 13 47, 8 46, 14 47, 15 0.124 0.169 0.464 0.334 1.13 0.816 1.57 -0.405 0.545 0.458 0.339 0.667 0.224 1.9 -0.181 0.485 0.709 0.149 0.834 0.32 2.12 0.279 0.479 0.56 0.252 1.32 0.529 3.35 PRS_PLINK_0.000199526231496888 TRUE 350.3 Lack of coordination Both 11 77 6 neurological darkblue 77, 11 20, 0 19, 5 19, 2 19, 4 -0.126 0.435 0.772 0.113 0.881 0.322 2.31 1 1.47 0.494 0.306 2.73 0.172 799 1.29 1.36 0.346 0.461 3.62 0.179 1590 0.562 1.25 0.652 0.186 1.75 0.113 2590 PRS_PLINK_0.000199526231496888 TRUE 350.5 Abnormal reflex Both 4 19 6 neurological darkblue 19, 4 5, 0 5, 3 4, 1 5, 0 -0.283 0.684 0.678 0.168 0.753 0.123 2.95 0.543 2.58 0.833 0.079 1.72 0.0119 12700 1.4 19.1 0.942 0.026 4.04 3.85 4.25 PRS_PLINK_0.000199526231496888 TRUE 350.6 Disturbances of sensation of smell and taste Both 2 40 6 neurological darkblue 40, 2 10, 0 10, 0 10, 0 10, 2 0.714 0.732 0.329 0.482 2.04 0.46 22.7 2.88 2.44 0.239 0.621 17.7 0.378 48300000 PRS_PLINK_0.000199526231496888 TRUE 351 Other peripheral nerve disorders Both 133 277 6 neurological darkblue 277, 133 70, 42 69, 28 69, 35 69, 27 -0.178 0.122 0.144 0.842 0.837 0.659 1.06 -0.401 0.353 0.257 0.591 0.67 0.334 1.32 -0.0955 0.319 0.765 0.116 0.909 0.489 1.69 -0.511 0.348 0.142 0.847 0.6 0.303 1.16 PRS_PLINK_0.000199526231496888 FALSE 352 Disorders of other cranial nerves Both 17 125 6 neurological darkblue 125, 17 32, 3 31, 4 31, 4 31, 6 0.123 0.281 0.662 0.179 1.13 0.644 2.02 -0.226 0.794 0.776 0.11 0.798 0.142 4.05 0.0383 0.767 0.96 0.018 1.04 0.208 5.13 0.315 0.826 0.703 0.153 1.37 0.254 7.65 PRS_PLINK_0.000199526231496888 TRUE 352.1 Trigeminal nerve disorders [CN5] Both 8 48 6 neurological darkblue 48, 8 12, 1 12, 2 12, 1 12, 4 0.341 0.482 0.479 0.319 1.41 0.558 4.54 0.00198 1.25 0.999 0.001 1 0.07 12.4 -0.885 1.53 0.562 0.25 0.413 6.93e-05 6.88 0.165 1.31 0.9 0.046 1.18 0.111 19.4 PRS_PLINK_0.000199526231496888 TRUE 352.2 Facial nerve disorders [CN7] Both 3 49 6 neurological darkblue 49, 3 13, 0 12, 0 12, 3 12, 0 0.511 0.599 0.393 0.405 1.67 0.484 40.5 1.56 1.37 0.257 0.591 4.75 0.424 8730 PRS_PLINK_0.000199526231496888 TRUE 353 Nerve root and plexus disorders Both 65 262 6 neurological darkblue 262, 65 66, 22 65, 16 65, 14 66, 13 -0.165 0.158 0.295 0.531 0.848 0.621 1.15 -0.185 0.429 0.666 0.176 0.831 0.356 1.91 -0.39 0.448 0.383 0.416 0.677 0.279 1.59 -0.594 0.463 0.199 0.701 0.552 0.215 1.34 PRS_PLINK_0.000199526231496888 FALSE 353.1 Nerve plexus lesions Both 7 42 6 neurological darkblue 42, 7 11, 2 10, 2 10, 2 11, 1 0.137 0.444 0.757 0.121 1.15 0.477 2.72 0.697 1.67 0.676 0.17 2.01 0.0478 1840 0.449 1.16 0.699 0.156 1.57 0.205 19.3 0.367 1.24 0.768 0.115 1.44 0.098 238 PRS_PLINK_0.000199526231496888 TRUE 353.2 Nerve root lesions Both 0 10 6 neurological darkblue 10, 0 3 2 2 3 PRS_PLINK_0.000199526231496888 TRUE 355 Complex regional/central pain syndrome Both 10 53 6 neurological darkblue 53, 10 14, 3 13, 1 13, 4 13, 2 -0.123 0.487 0.8 0.097 0.884 0.301 2.32 -0.467 1.36 0.732 0.135 0.627 0.00623 91.3 0.419 1.27 0.742 0.13 1.52 0.112 19.9 -0.422 1.59 0.79 0.102 0.656 0.0068 25.2 PRS_PLINK_0.000199526231496888 TRUE 355.1 Chronic pain syndrome Both 13 84 6 neurological darkblue 84, 13 21, 4 21, 2 21, 1 21, 6 0.222 0.322 0.49 0.31 1.25 0.67 2.37 -0.463 0.958 0.629 0.201 0.629 0.083 3.89 1.12 1.43 0.433 0.363 3.07 0.154 1e+05 0.152 0.819 0.853 0.069 1.16 0.245 5.61 PRS_PLINK_0.000199526231496888 TRUE 356 Hereditary and idiopathic peripheral neuropathy Both 53 107 6 neurological darkblue 107, 53 27, 18 27, 18 26, 9 27, 8 -0.38 0.226 0.0926 1.034 0.684 0.43 1.06 -0.247 0.567 0.663 0.178 0.781 0.252 2.31 -1.02 0.751 0.176 0.755 0.362 0.069 1.5 -0.916 0.719 0.202 0.694 0.4 0.0859 1.57 PRS_PLINK_0.000199526231496888 FALSE 357 Inflammatory and toxic neuropathy Both 65 162 6 neurological darkblue 162, 65 41, 20 40, 21 40, 10 41, 14 -0.151 0.18 0.399 0.399 0.859 0.602 1.22 -0.0185 0.436 0.966 0.015 0.982 0.424 2.26 -0.494 0.56 0.377 0.424 0.61 0.199 1.79 -0.67 0.58 0.248 0.606 0.512 0.154 1.55 PRS_PLINK_0.000199526231496888 FALSE 358 Myoneural disorders Both 18 92 6 neurological darkblue 92, 18 23, 4 23, 2 23, 8 23, 4 0.166 0.348 0.634 0.198 1.18 0.581 2.41 0.0326 0.939 0.972 0.012 1.03 0.141 8.7 1.04 0.906 0.249 0.604 2.84 0.526 31.7 -0.228 1.15 0.842 0.075 0.796 0.0555 44 PRS_PLINK_0.000199526231496888 TRUE 358.1 Myasthenia gravis Both 1 7 6 neurological darkblue 7, 1 2, 1 2, 0 1, 0 2, 0 1.19 67.3 0.986 0.006 3.28 0.00471 216000 0.0705 853 1 0 1.07 0.665 2.09 -0.137 1950 1 0 0.872 0.29 1.63 0.281 3690 1 0 1.32 0.5 8.84 PRS_PLINK_0.000199526231496888 TRUE 359 Muscular dystrophies and other myopathies Both 26 90 6 neurological darkblue 90, 26 22, 5 22, 11 22, 7 23, 3 -0.123 0.238 0.603 0.219 0.884 0.552 1.41 0.701 0.669 0.294 0.531 2.02 0.601 7.58 0.0715 0.722 0.921 0.036 1.07 0.27 4.31 -0.418 0.952 0.661 0.18 0.658 0.0708 4.56 PRS_PLINK_0.000199526231496888 TRUE 359.1 Muscular dystrophies Both 0 8 6 neurological darkblue 8, 0 2 2 2 2 PRS_PLINK_0.000199526231496888 TRUE 359.2 Myopathy Both 26 87 6 neurological darkblue 87, 26 21, 5 22, 11 21, 6 22, 4 -0.132 0.238 0.579 0.238 0.876 0.549 1.39 0.776 0.687 0.259 0.587 2.17 0.636 8.58 0.243 0.748 0.745 0.128 1.28 0.316 5.4 -0.338 0.945 0.721 0.142 0.714 0.0752 4.64 PRS_PLINK_0.000199526231496888 TRUE 360 Disorders of the globe Both 4 10 7 sense organs darkseagreen4 10, 4 3, 2 2, 1 2, 0 3, 1 0.0954 1.12 0.932 0.03 1.1 0.173 7.67 1.92 26.1 0.941 0.026 6.83 0.0989 507 -2.22 2250000 1 0 0.109 0.00212 4.09 0.296 3.43 0.931 0.031 1.34 1.13 1.43 PRS_PLINK_0.000199526231496888 TRUE 360.2 Progressive myopia Both 3 9 7 sense organs darkseagreen4 9, 3 3, 1 2, 0 2, 1 2, 1 0.139 1.09 0.898 0.047 1.15 0.208 38 0.0347 10100 1 0 1.04 0.255 5.09 -0.129 2570 1 0 0.879 0.295 1.59 -2.24e-05 6450 1 0 1 0.265 2.73 PRS_PLINK_0.000199526231496888 TRUE 361 Retinal detachments and defects Both 2 28 7 sense organs darkseagreen4 28, 2 7, 0 7, 2 7, 0 7, 0 -0.354 0.719 0.623 0.206 0.702 1.58e-05 2.82 0.134 2.23 0.952 0.021 1.14 0.00618 82.1 PRS_PLINK_0.000199526231496888 TRUE 361.1 Retinal detachment with retinal defect Both 0 12 7 sense organs darkseagreen4 12, 0 3 3 3 3 PRS_PLINK_0.000199526231496888 TRUE 362 Other retinal disorders Both 32 130 7 sense organs darkseagreen4 130, 32 33, 9 32, 7 32, 5 33, 11 0.0443 0.193 0.818 0.087 1.05 0.719 1.52 -0.312 0.633 0.622 0.206 0.732 0.205 2.43 -0.437 0.6 0.467 0.331 0.646 0.191 2.02 0.456 0.538 0.396 0.402 1.58 0.574 4.53 PRS_PLINK_0.000199526231496888 TRUE 362.2 Degeneration of macula and posterior pole of retina Both 18 74 7 sense organs darkseagreen4 74, 18 19, 3 18, 5 18, 3 19, 7 0.298 0.262 0.256 0.592 1.35 0.822 2.29 0.942 0.944 0.318 0.497 2.56 0.411 23.3 -0.119 0.958 0.901 0.045 0.888 0.114 5.26 0.948 0.806 0.24 0.62 2.58 0.612 13.8 PRS_PLINK_0.000199526231496888 TRUE 362.21 Macular degeneration, dry Both 2 11 7 sense organs darkseagreen4 11, 2 3, 0 3, 1 2, 0 3, 1 0.237 1.15 0.836 0.078 1.27 0.204 16.1 0.13 969 1 0 1.14 0.471 1.66 -0.78 3760000 1 0 0.459 0.0169 16.8 PRS_PLINK_0.000199526231496888 TRUE 362.22 Macular degeneration, wet Both 1 2 7 sense organs darkseagreen4 2, 1 1, 0 0, 1 1, 0 1, 0 -0.000544 607 1 0 0.999 0.992 1.01 -0.00216 273 1 0 0.998 0.996 1 PRS_PLINK_0.000199526231496888 TRUE 362.23 Cystoid macular degeneration of retina Both 5 19 7 sense organs darkseagreen4 19, 5 5, 1 5, 0 4, 2 5, 2 0.0022 0.492 0.996 0.002 1 0.408 2.33 -0.683 2.23 0.76 0.119 0.505 0.00952 11 0.882 3.93 0.823 0.085 2.42 0.000126 1530 -0.664 1.97 0.737 0.133 0.515 0.00513 32.3 PRS_PLINK_0.000199526231496888 TRUE 362.26 Macular puckering of retina Both 6 38 7 sense organs darkseagreen4 38, 6 10, 1 9, 0 9, 2 10, 3 0.37 0.44 0.401 0.397 1.45 0.624 4 -1.02 1.85 0.58 0.236 0.36 0.000706 8.69 -0.471 1.55 0.761 0.119 0.625 0.000249 114 -0.516 1.52 0.734 0.134 0.597 0.000968 34.9 PRS_PLINK_0.000199526231496888 TRUE 362.27 Drusen (degenerative) of retina Both 3 22 7 sense organs darkseagreen4 22, 3 6, 1 5, 1 5, 1 6, 0 0.743 0.971 0.444 0.353 2.1 0.389 112 1.14 1.96 0.559 0.253 3.14 0.034 249 2.65 3.9 0.498 0.303 14.1 0.00925 157000 -0.884 3.4 0.795 0.1 0.413 0.000376 151 PRS_PLINK_0.000199526231496888 TRUE 362.29 Macular degeneration (senile) of retina NOS Both 15 67 7 sense organs darkseagreen4 67, 15 17, 3 17, 4 16, 2 17, 6 0.276 0.28 0.325 0.489 1.32 0.777 2.33 0.373 0.865 0.667 0.176 1.45 0.277 8.72 -0.714 1.15 0.536 0.271 0.49 0.0185 5.92 0.883 0.83 0.287 0.542 2.42 0.559 13.1 PRS_PLINK_0.000199526231496888 TRUE 362.3 Other nondiabetic retinopathy Both 10 41 7 sense organs darkseagreen4 41, 10 11, 4 10, 3 10, 1 10, 2 -0.0471 0.414 0.909 0.041 0.954 0.434 2.11 0.62 1.06 0.56 0.252 1.86 0.207 2.27 0.227 1.31 0.863 0.064 1.25 0.113 21.9 1.52 1.57 0.336 0.474 4.55 0.225 242 PRS_PLINK_0.000199526231496888 TRUE 362.31 Separation of retinal layers Both 3 17 7 sense organs darkseagreen4 17, 3 5, 2 4, 1 4, 0 4, 0 -0.00889 1.26 0.994 0.002 0.991 0.0406 4190 0.129 3.24 0.968 0.014 1.14 0.00242 2230000 -0.338 2 0.866 0.063 0.713 0.00844 0.835 3.29 8.06 0.683 0.166 26.9 1.05 34.4 PRS_PLINK_0.000199526231496888 TRUE 362.4 Retinal vascular changes and abnomalities Both 11 31 7 sense organs darkseagreen4 31, 11 8, 2 8, 1 7, 2 8, 6 0.451 0.472 0.339 0.47 1.57 0.623 4.59 0.0814 1.86 0.965 0.015 1.08 0.00722 50.7 -0.0668 2.22 0.976 0.011 0.935 0.00103 287 2.3 1.85 0.214 0.669 9.99 0.376 129000 PRS_PLINK_0.000199526231496888 TRUE 362.6 Peripheral retinal degenerations Both 5 26 7 sense organs darkseagreen4 26, 5 7, 1 6, 2 6, 2 7, 0 -0.597 0.574 0.299 0.525 0.551 0.0243 1.52 1.04 1.9 0.585 0.233 2.82 0.0162 1600 -1.15 3.46 0.739 0.131 0.315 1.81e-05 274000 -0.742 1.73 0.668 0.176 0.476 0.0098 9.36 PRS_PLINK_0.000199526231496888 TRUE 362.7 Hereditary retinal dystrophies Both 3 10 7 sense organs darkseagreen4 10, 3 3, 1 2, 0 2, 0 3, 2 0.485 1.18 0.682 0.166 1.62 1.52 1.7 0.0738 9380 1 0 1.08 0.0909 13.9 0.993 17800000 1 0 2.7 8.53e-08 55800000 2.9 3.77 0.442 0.354 18.1 17.9 39.4 PRS_PLINK_0.000199526231496888 TRUE 362.8 Retinal hemorrhage/ischemia Both 5 15 7 sense organs darkseagreen4 15, 5 4, 0 4, 1 3, 1 4, 3 1.23 0.786 0.118 0.927 3.41 0.996 73.5 -0.378 253 0.999 0.001 0.685 0.0257 88.3 1.17 379 0.998 0.001 3.22 0.000208 63300 3.9 6.88 0.571 0.243 49.2 0.000337 4820000 PRS_PLINK_0.000199526231496888 TRUE 362.9 Retinal edema Both 3 22 7 sense organs darkseagreen4 22, 3 6, 0 5, 1 5, 0 6, 2 0.258 0.773 0.738 0.132 1.29 0.076 12.7 0.351 3.23 0.914 0.039 1.42 0.00491 18000 0.866 1.96 0.658 0.182 2.38 0.0554 199 PRS_PLINK_0.000199526231496888 TRUE 363 Chorioretinal inflammations, scars, and other disorders of choroid Both 1 32 7 sense organs darkseagreen4 32, 1 8, 0 8, 0 8, 0 8, 1 0.557 0.606 0.358 0.446 1.74 0.327 14.3 0.476 1.84 0.796 0.099 1.61 0.0123 223 PRS_PLINK_0.000199526231496888 TRUE 363.3 Chorioretinal scars Both 1 22 7 sense organs darkseagreen4 22, 1 6, 0 5, 0 5, 0 6, 1 0.0534 1.02 0.958 0.019 1.05 0.123 58.3 -0.0878 2.47 0.972 0.012 0.916 0.00793 467 PRS_PLINK_0.000199526231496888 TRUE 364 Corneal opacity and other disorders of cornea Both 12 73 7 sense organs darkseagreen4 73, 12 19, 3 18, 2 18, 1 18, 6 -0.241 0.342 0.481 0.318 0.786 0.382 1.58 -0.853 1.06 0.421 0.375 0.426 0.0344 6.01 -0.682 0.982 0.487 0.312 0.505 0.0543 3.34 -0.00832 0.911 0.993 0.003 0.992 0.15 6.03 PRS_PLINK_0.000199526231496888 TRUE 364.1 Corneal opacity Both 5 19 7 sense organs darkseagreen4 19, 5 5, 0 5, 1 4, 0 5, 4 0.795 1.14 0.487 0.312 2.22 0.185 2080 0.628 2.13 0.768 0.114 1.87 1.63 2.13 0.515 1.85 0.781 0.107 1.67 0.143 61.8 PRS_PLINK_0.000199526231496888 TRUE 364.2 Corneal edema Both 0 9 7 sense organs darkseagreen4 9, 0 3 2 2 2 PRS_PLINK_0.000199526231496888 TRUE 364.4 Corneal degenerations Both 6 27 7 sense organs darkseagreen4 27, 6 7, 3 7, 1 6, 1 7, 1 -0.821 0.607 0.177 0.753 0.44 0.091 1.33 -1.14 1.74 0.512 0.291 0.32 0.00113 4.6 2.23 2.5 0.374 0.428 9.28 0.174 1520 -0.271 2.71 0.921 0.036 0.763 0.00304 191 PRS_PLINK_0.000199526231496888 TRUE 364.41 Keratoconus Both 0 2 7 sense organs darkseagreen4 2, 0 1 1 1 1 PRS_PLINK_0.000199526231496888 TRUE 364.5 Corneal dystrophy Both 4 22 7 sense organs darkseagreen4 22, 4 6, 1 5, 0 5, 1 6, 2 -0.518 0.824 0.53 0.276 0.596 0.00328 4.03 -0.805 3.35 0.81 0.092 0.447 1.6e-05 875 -0.51 2.24 0.82 0.086 0.6 0.00449 23.2 0.604 2.84 0.831 0.08 1.83 9.73e-05 64900 PRS_PLINK_0.000199526231496888 TRUE 364.51 Fuchs' dystrophy Both 2 11 7 sense organs darkseagreen4 11, 2 3, 0 3, 0 2, 0 3, 2 0.0367 1.96 0.985 0.007 1.04 0.00604 52.7 0.0289 1240 1 0 1.03 0.278 1.23 PRS_PLINK_0.000199526231496888 TRUE 364.9 Cornea replaced by transplant Both 0 6 7 sense organs darkseagreen4 6, 0 2 1 1 2 PRS_PLINK_0.000199526231496888 TRUE 365 Glaucoma Both 19 128 7 sense organs darkseagreen4 128, 19 32, 3 32, 5 32, 7 32, 4 0.197 0.243 0.418 0.379 1.22 0.753 2 0.693 0.81 0.392 0.407 2 0.418 11.7 0.486 0.686 0.478 0.32 1.63 0.427 7.06 0.72 0.806 0.371 0.43 2.05 0.422 11 PRS_PLINK_0.000199526231496888 TRUE 365.1 Open-angle glaucoma Both 9 21 7 sense organs darkseagreen4 21, 9 6, 1 5, 0 5, 3 5, 5 0.57 0.434 0.189 0.723 1.77 0.871 5.14 -2.19 6.69 0.744 0.129 0.112 8.04e-07 1.11e+08 0.497 1.68 0.768 0.115 1.64 0.136 63.6 1.39 1.57 0.377 0.424 4.02 0.371 1180 PRS_PLINK_0.000199526231496888 TRUE 365.11 Primary open angle glaucoma Both 6 11 7 sense organs darkseagreen4 11, 6 3, 1 3, 0 2, 4 3, 1 1.68 2.16 0.436 0.361 5.37 0.26 6.05 0.0304 6160 1 0 1.03 0.354 3.09 1.31 3.16 0.678 0.169 3.72 0.0523 857 0.0649 16500000 1 0 1.07 0.12 16.8 PRS_PLINK_0.000199526231496888 TRUE 365.2 Primary angle-closure glaucoma Both 0 14 7 sense organs darkseagreen4 14, 0 4 3 3 4 PRS_PLINK_0.000199526231496888 TRUE 366 Cataract Both 70 181 7 sense organs darkseagreen4 181, 70 45, 18 45, 18 45, 18 45, 16 -0.121 0.169 0.472 0.326 0.886 0.637 1.23 0.26 0.483 0.591 0.229 1.3 0.513 3.38 -0.111 0.466 0.812 0.091 0.895 0.364 2.19 -0.106 0.502 0.833 0.079 0.9 0.34 2.37 PRS_PLINK_0.000199526231496888 FALSE 366.1 Nonsenile Cataract Both 3 9 7 sense organs darkseagreen4 9, 3 3, 2 2, 0 2, 1 2, 0 -0.104 1.11 0.925 0.034 0.901 0.131 5.32 -0.218 935 1 0 0.804 0.32 1.62 -0.0191 3100 1 0 0.981 0.0585 2.05 -2.69 1180 0.998 0.001 0.0676 1.4e-07 10900 PRS_PLINK_0.000199526231496888 TRUE 366.2 Senile cataract Both 55 130 7 sense organs darkseagreen4 130, 55 32, 18 32, 13 32, 12 33, 12 -0.248 0.193 0.198 0.703 0.78 0.535 1.13 -0.0569 0.535 0.915 0.038 0.945 0.332 2.71 -0.291 0.507 0.566 0.247 0.748 0.281 1.95 -0.379 0.555 0.495 0.305 0.685 0.231 1.95 PRS_PLINK_0.000199526231496888 FALSE 367 Disorders of refraction and accommodation; blindness and low vision Both 168 285 7 sense organs darkseagreen4 285, 168 71, 47 71, 45 71, 27 71, 49 -0.106 0.105 0.312 0.506 0.899 0.733 1.1 -0.019 0.285 0.947 0.024 0.981 0.565 1.7 -0.672 0.314 0.0327 1.485 0.511 0.276 0.928 -0.106 0.295 0.72 0.143 0.899 0.507 1.59 PRS_PLINK_0.000199526231496888 FALSE 367.1 Myopia Both 109 275 7 sense organs darkseagreen4 275, 109 68, 36 69, 30 68, 18 69, 25 -0.243 0.121 0.0452 1.345 0.784 0.618 0.99 -0.176 0.316 0.578 0.238 0.839 0.454 1.54 -0.924 0.367 0.0118 1.929 0.397 0.191 0.792 -0.424 0.338 0.209 0.68 0.654 0.337 1.25 PRS_PLINK_0.000199526231496888 FALSE 367.2 Astigmatism Both 82 254 7 sense organs darkseagreen4 254, 82 63, 24 63, 23 63, 15 64, 20 -0.199 0.139 0.153 0.816 0.819 0.624 1.07 -0.0167 0.367 0.964 0.016 0.983 0.482 2 -0.639 0.394 0.105 0.98 0.528 0.242 1.11 -0.325 0.384 0.397 0.402 0.722 0.339 1.51 PRS_PLINK_0.000199526231496888 FALSE 367.8 Hypermetropia Both 30 102 7 sense organs darkseagreen4 102, 30 26, 8 25, 11 25, 1 26, 10 -0.0953 0.228 0.676 0.17 0.909 0.585 1.42 0.262 0.579 0.651 0.186 1.3 0.434 3.91 -1.36 0.876 0.122 0.915 0.258 0.0278 1.23 -0.0265 0.637 0.967 0.015 0.974 0.285 3.25 PRS_PLINK_0.000199526231496888 TRUE 367.9 Blindness and low vision Both 18 64 7 sense organs darkseagreen4 64, 18 16, 3 16, 5 16, 3 16, 7 0.265 0.279 0.342 0.466 1.3 0.773 2.26 0.739 0.835 0.376 0.425 2.09 0.467 11.5 -0.178 1.03 0.862 0.064 0.837 0.119 6.62 0.769 0.79 0.33 0.481 2.16 0.526 10.8 PRS_PLINK_0.000199526231496888 TRUE 368 Visual disturbances Both 92 354 7 sense organs darkseagreen4 354, 92 88, 27 88, 21 88, 19 89, 25 -0.00818 0.123 0.947 0.024 0.992 0.78 1.26 -0.142 0.346 0.682 0.166 0.868 0.44 1.7 -0.254 0.351 0.469 0.329 0.775 0.388 1.53 -0.0727 0.339 0.83 0.081 0.93 0.482 1.79 PRS_PLINK_0.000199526231496888 FALSE 368.1 Amblyopia Both 14 47 7 sense organs darkseagreen4 47, 14 12, 3 12, 7 11, 2 12, 2 -0.124 0.304 0.684 0.165 0.883 0.498 1.56 2.29 1.27 0.0713 1.147 9.84 1.09 237 0.25 1.16 0.83 0.081 1.28 0.135 15.1 0.0762 1.35 0.955 0.02 1.08 0.0668 22 PRS_PLINK_0.000199526231496888 TRUE 368.2 Diplopia and disorders of binocular vision Both 13 73 7 sense organs darkseagreen4 73, 13 19, 3 18, 4 18, 3 18, 3 0.0129 0.296 0.965 0.015 1.01 0.575 1.8 0.586 0.899 0.514 0.289 1.8 0.324 12.7 0.0791 1.02 0.938 0.028 1.08 0.117 9.7 0.296 0.971 0.761 0.119 1.34 0.202 11 PRS_PLINK_0.000199526231496888 TRUE 368.3 Anisometropia Both 6 11 7 sense organs darkseagreen4 11, 6 3, 3 3, 1 2, 1 3, 1 -0.355 0.991 0.72 0.143 0.701 0.112 3.46 2.12 145 0.988 0.005 8.34 12.3 5930000 0.554 6550 1 0 1.74 1.06 19.1 -1.19 4.99 0.811 0.091 0.303 0.156 0.155 PRS_PLINK_0.000199526231496888 TRUE 368.4 Visual field defects Both 14 67 7 sense organs darkseagreen4 67, 14 17, 6 17, 3 16, 2 17, 3 -0.262 0.305 0.39 0.409 0.769 0.414 1.36 -0.374 0.84 0.656 0.183 0.688 0.135 3.26 -0.684 0.84 0.415 0.382 0.504 0.0892 2.93 -0.553 0.858 0.519 0.285 0.575 0.102 2.83 PRS_PLINK_0.000199526231496888 TRUE 368.9 Subjective visual disturbances Both 22 84 7 sense organs darkseagreen4 84, 22 21, 7 21, 5 21, 2 21, 8 0.0778 0.281 0.782 0.107 1.08 0.628 1.88 0.0671 0.708 0.924 0.034 1.07 0.281 4.33 -0.843 0.816 0.301 0.521 0.43 0.0749 1.87 -0.205 0.708 0.772 0.113 0.814 0.21 3.08 PRS_PLINK_0.000199526231496888 TRUE 368.91 Psychophysical visual disturbances Both 3 2 7 sense organs darkseagreen4 2, 3 1, 3 1, 0 1, 3 1, 0 0.308 3720 1 0 1.36 0.156 2.24 0.104 792 1 0 1.11 0.65 1.42 PRS_PLINK_0.000199526231496888 TRUE 369 Infection of the eye Both 84 272 7 sense organs darkseagreen4 272, 84 67, 15 68, 23 68, 20 68, 26 0.115 0.13 0.378 0.423 1.12 0.872 1.45 0.348 0.387 0.369 0.433 1.42 0.673 3.03 0.0585 0.39 0.881 0.055 1.06 0.497 2.28 0.322 0.387 0.405 0.392 1.38 0.657 2.95 PRS_PLINK_0.000199526231496888 FALSE 369.2 Eye infection, viral Both 8 49 7 sense organs darkseagreen4 49, 8 13, 0 12, 1 12, 5 12, 2 0.259 0.384 0.5 0.301 1.3 0.637 2.78 0.896 1.47 0.543 0.265 2.45 0.137 424 2.07 1.64 0.206 0.687 7.92 0.54 15800 1.5 1.56 0.335 0.475 4.49 0.215 1.62e+08 PRS_PLINK_0.000199526231496888 TRUE 369.5 Conjunctivitis, infectious Both 77 241 7 sense organs darkseagreen4 241, 77 60, 14 60, 22 60, 19 60, 22 0.0752 0.136 0.582 0.235 1.08 0.829 1.41 0.411 0.402 0.306 0.514 1.51 0.698 3.32 0.147 0.4 0.713 0.147 1.16 0.535 2.54 0.142 0.411 0.73 0.137 1.15 0.522 2.57 PRS_PLINK_0.000199526231496888 FALSE 370 Keratitis Both 15 106 7 sense organs darkseagreen4 106, 15 26, 4 26, 5 26, 2 27, 4 -0.272 0.276 0.325 0.488 0.762 0.432 1.33 0.21 0.863 0.808 0.093 1.23 0.207 6.88 -0.752 0.951 0.429 0.367 0.471 0.0404 3.64 -0.366 0.79 0.643 0.192 0.693 0.123 3.19 PRS_PLINK_0.000199526231496888 TRUE 370.1 Corneal ulcer Both 2 23 7 sense organs darkseagreen4 23, 2 6, 0 6, 0 5, 1 6, 1 0.859 0.808 0.288 0.541 2.36 0.594 175 -0.76 4.21 0.857 0.067 0.468 2.24e-06 28500 2.08 2.31 0.369 0.433 7.99 0.293 9050 PRS_PLINK_0.000199526231496888 TRUE 370.2 Superficial keratitis Both 6 44 7 sense organs darkseagreen4 44, 6 10, 2 11, 3 11, 0 11, 1 -0.453 0.451 0.315 0.502 0.636 0.241 1.87 0.786 1.18 0.507 0.295 2.19 0.263 39.7 -0.483 1.55 0.756 0.121 0.617 0.0254 15.2 -0.0991 1.43 0.945 0.025 0.906 0.0145 75.7 PRS_PLINK_0.000199526231496888 TRUE 370.3 Keratoconjunctivitis Both 5 46 7 sense organs darkseagreen4 46, 5 12, 0 11, 2 11, 0 12, 3 0.794 0.791 0.315 0.501 2.21 0.447 68.3 0.425 1.69 0.801 0.096 1.53 0.00875 8550 0.612 1.47 0.677 0.169 1.84 0.121 637 PRS_PLINK_0.000199526231496888 TRUE 370.31 Keratoconjunctivitis sicca Both 1 12 7 sense organs darkseagreen4 12, 1 3, 0 3, 0 3, 1 3, 0 -0.18 1.09 0.868 0.061 0.835 0.00963 8 0.316 2830 1 0 1.37 0.281 5.65 PRS_PLINK_0.000199526231496888 TRUE 371 Inflammation of the eye Both 67 251 7 sense organs darkseagreen4 251, 67 62, 12 63, 20 62, 17 63, 18 0.108 0.148 0.466 0.332 1.11 0.837 1.49 0.379 0.436 0.385 0.414 1.46 0.63 3.47 0.187 0.444 0.674 0.171 1.21 0.51 2.88 0.272 0.44 0.536 0.271 1.31 0.56 3.13 PRS_PLINK_0.000199526231496888 FALSE 371.1 Uveitis, noninfectious or NOS Both 5 41 7 sense organs darkseagreen4 41, 5 11, 1 10, 1 10, 2 10, 1 0.29 0.424 0.495 0.306 1.34 0.59 3.22 0.00769 1.29 0.995 0.002 1.01 0.0571 11.9 0.56 1.82 0.759 0.12 1.75 0.008 1410 -0.168 1.45 0.908 0.042 0.846 0.0149 27.9 PRS_PLINK_0.000199526231496888 TRUE 371.2 Conjunctivitis, noninfectious Both 24 77 7 sense organs darkseagreen4 77, 24 20, 3 19, 8 19, 4 19, 9 0.0562 0.25 0.822 0.085 1.06 0.655 1.72 0.686 0.81 0.397 0.401 1.99 0.44 10.3 0.212 0.833 0.8 0.097 1.24 0.243 6.52 0.873 0.798 0.274 0.563 2.39 0.552 13.1 PRS_PLINK_0.000199526231496888 TRUE 371.21 Allergic conjunctivitis Both 20 62 7 sense organs darkseagreen4 62, 20 16, 3 15, 7 15, 1 16, 9 0.0646 0.279 0.817 0.088 1.07 0.625 1.85 0.275 0.93 0.768 0.115 1.32 0.229 8.2 -1.05 1.14 0.357 0.448 0.349 0.0256 2.76 0.79 0.83 0.342 0.466 2.2 0.498 11.5 PRS_PLINK_0.000199526231496888 TRUE 371.3 Inflammation of eyelids Both 45 164 7 sense organs darkseagreen4 164, 45 40, 9 41, 14 41, 11 41, 11 0.12 0.186 0.517 0.286 1.13 0.788 1.62 0.381 0.51 0.456 0.341 1.46 0.553 4.04 0.144 0.531 0.787 0.104 1.15 0.411 3.28 0.115 0.527 0.827 0.083 1.12 0.408 3.11 PRS_PLINK_0.000199526231496888 TRUE 371.33 Noninfectious dermatoses of eyelid Both 4 6 7 sense organs darkseagreen4 6, 4 2, 2 1, 0 1, 1 2, 1 -0.0444 0.954 0.963 0.016 0.957 0.857 1.03 0.754 802 0.999 0 2.12 0.628 25.1 -1.24 521 0.998 0.001 0.289 0.00104 51.1 -0.0024 21.7 1 0 0.998 0.936 1.06 PRS_PLINK_0.000199526231496888 TRUE 372 Disorders of conjunctiva Both 12 56 7 sense organs darkseagreen4 56, 12 13, 1 14, 5 14, 4 14, 2 0.103 0.333 0.756 0.121 1.11 0.556 2.2 1.78 1.39 0.202 0.694 5.91 0.448 252 0.686 1.14 0.547 0.262 1.99 0.172 23.9 -0.257 1.12 0.818 0.087 0.774 0.0529 6.79 PRS_PLINK_0.000199526231496888 TRUE 374 Other disorders of eyelids Both 36 131 7 sense organs darkseagreen4 131, 36 33, 10 33, 9 32, 7 33, 10 0.0609 0.184 0.74 0.131 1.06 0.743 1.52 0.122 0.548 0.825 0.084 1.13 0.394 3.3 -0.285 0.605 0.638 0.195 0.752 0.221 2.38 0.208 0.538 0.7 0.155 1.23 0.445 3.46 PRS_PLINK_0.000199526231496888 TRUE 374.1 Ectropion or entropion Both 6 12 7 sense organs darkseagreen4 12, 6 3, 3 3, 1 3, 0 3, 2 0.378 0.665 0.569 0.245 1.46 0.523 8.32 1.8 9.1 0.843 0.074 6.07 1.59e-05 8.01 -1.03 276 0.997 0.001 0.357 0.0557 0.47 -0.32 17.1 0.985 0.007 0.726 0.0161 32.7 PRS_PLINK_0.000199526231496888 TRUE 374.2 Lagophthalmos Both 2 8 7 sense organs darkseagreen4 8, 2 2, 1 2, 0 2, 0 2, 1 -0.51 1.63 0.754 0.123 0.6 0.0467 7.16 0.317 3440 1 0 1.37 0.584 1.58 0.0479 929 1 0 1.05 0.638 1.33 0.439 3930 1 0 1.55 0.775 3.06 PRS_PLINK_0.000199526231496888 TRUE 374.3 Ptosis of eyelid Both 8 42 7 sense organs darkseagreen4 42, 8 11, 3 10, 2 10, 0 11, 3 -0.378 0.389 0.331 0.48 0.685 0.273 1.38 1.36 1.6 0.395 0.403 3.88 0.101 992 -1.43 1.36 0.296 0.529 0.24 0.00177 3.37 0.384 1.34 0.775 0.111 1.47 0.131 284 PRS_PLINK_0.000199526231496888 TRUE 374.6 Dermatochalasis Both 11 33 7 sense organs darkseagreen4 33, 11 9, 4 8, 2 8, 3 8, 2 -0.155 0.394 0.694 0.158 0.857 0.38 1.77 -0.298 1.24 0.81 0.092 0.742 0.0135 6.74 -0.33 1.07 0.758 0.12 0.719 0.0862 4.26 -0.357 1.52 0.814 0.09 0.699 0.00148 6.88 PRS_PLINK_0.000199526231496888 TRUE 375 Disorders of lacrimal system Both 54 197 7 sense organs darkseagreen4 197, 54 49, 15 49, 14 49, 13 49, 12 -0.0691 0.166 0.678 0.169 0.933 0.673 1.29 0.0433 0.483 0.928 0.032 1.04 0.405 2.69 -0.382 0.475 0.421 0.376 0.682 0.266 1.7 -0.0282 0.491 0.954 0.02 0.972 0.372 2.53 PRS_PLINK_0.000199526231496888 FALSE 375.1 Dry eyes Both 56 214 7 sense organs darkseagreen4 214, 56 53, 16 53, 14 53, 11 54, 15 -0.019 0.163 0.907 0.042 0.981 0.714 1.35 0.00108 0.467 0.998 0.001 1 0.4 2.5 -0.538 0.477 0.259 0.586 0.584 0.225 1.46 0.119 0.459 0.796 0.099 1.13 0.464 2.75 PRS_PLINK_0.000199526231496888 FALSE 375.2 Epiphora Both 5 23 7 sense organs darkseagreen4 23, 5 6, 1 6, 0 5, 2 6, 2 0.448 0.727 0.537 0.27 1.57 0.392 22.1 -1.23 2.57 0.633 0.199 0.293 0.000573 13.6 1.29 1.87 0.489 0.311 3.64 0.171 128 -0.652 3.47 0.851 0.07 0.521 1.28e-09 479 PRS_PLINK_0.000199526231496888 TRUE 376 Disorders of the orbit Both 2 29 7 sense organs darkseagreen4 29, 2 8, 0 7, 1 7, 1 7, 0 0.0558 0.606 0.927 0.033 1.06 0.311 4.79 0.82 2.01 0.684 0.165 2.27 0.0297 272 1.34 2.2 0.543 0.265 3.82 0.0934 2450 PRS_PLINK_0.000199526231496888 TRUE 377 Disorders of optic nerve and visual pathways Both 9 74 7 sense organs darkseagreen4 74, 9 19, 1 18, 3 18, 3 19, 2 0.197 0.338 0.559 0.253 1.22 0.618 2.46 1.55 1.24 0.213 0.672 4.71 0.492 662 0.63 1.06 0.552 0.258 1.88 0.155 28.9 0.193 1.25 0.877 0.057 1.21 0.0604 21.7 PRS_PLINK_0.000199526231496888 TRUE 377.1 Optic atrophy Both 4 17 7 sense organs darkseagreen4 17, 4 5, 1 4, 1 4, 1 4, 1 -0.116 0.587 0.844 0.074 0.891 0.14 5.41 -2.81 6.75 0.677 0.169 0.0602 0.0481 919 -1.23 7.74 0.874 0.059 0.292 4.85e-06 14200 -2.59 47.3 0.956 0.019 0.075 0.0639 0.0877 PRS_PLINK_0.000199526231496888 TRUE 377.3 Optic neuritis/neuropathy Both 5 54 7 sense organs darkseagreen4 54, 5 14, 0 13, 1 13, 2 14, 2 0.576 0.439 0.189 0.724 1.78 0.781 5.62 0.717 1.22 0.557 0.254 2.05 0.137 3500 -0.221 1.53 0.885 0.053 0.802 0.00625 180 1.3 1.22 0.284 0.547 3.68 0.337 332 PRS_PLINK_0.000199526231496888 TRUE 378 Strabismus and other disorders of binocular eye movements Both 11 84 7 sense organs darkseagreen4 84, 11 21, 3 21, 1 21, 4 21, 3 0.126 0.333 0.705 0.152 1.13 0.579 2.32 -1.27 1.14 0.268 0.572 0.282 0.234 2.31 -0.261 0.894 0.771 0.113 0.771 0.122 4.63 0.184 0.924 0.842 0.075 1.2 0.172 7.99 PRS_PLINK_0.000199526231496888 TRUE 378.1 Strabismus (not specified as paralytic) Both 8 56 7 sense organs darkseagreen4 56, 8 14, 3 14, 0 14, 3 14, 2 -0.545 0.449 0.225 0.649 0.58 0.185 1.49 -2.23 1.75 0.203 0.692 0.108 3.71e-05 2.54 -1.44 1.28 0.261 0.583 0.236 0.00858 2.17 -2.39 1.83 0.193 0.714 0.092 5.57e-10 2.56 PRS_PLINK_0.000199526231496888 TRUE 378.2 Nystagmus and other irregular eye movements Both 2 11 7 sense organs darkseagreen4 11, 2 3, 0 3, 1 2, 1 3, 0 0.375 0.932 0.687 0.163 1.45 0.0479 9.74 0.386 6390000 1 0 1.47 0.054 59 0.107 2690 1 0 1.11 0.554 1.25 PRS_PLINK_0.000199526231496888 TRUE 378.5 Paralytic strabismus Both 1 20 7 sense organs darkseagreen4 20, 1 5, 0 5, 0 5, 0 5, 1 0.597 0.799 0.455 0.342 1.82 0.403 18.4 2.25 3.91 0.565 0.248 9.51 0.0411 82.3 PRS_PLINK_0.000199526231496888 TRUE 379 Other disorders of eye Both 63 205 7 sense organs darkseagreen4 205, 63 51, 13 51, 11 51, 18 51, 21 0.3 0.157 0.0558 1.253 1.35 0.999 1.84 -0.059 0.494 0.905 0.043 0.943 0.356 2.45 0.363 0.445 0.415 0.382 1.44 0.612 3.45 0.569 0.428 0.184 0.736 1.77 0.784 4.09 PRS_PLINK_0.000199526231496888 FALSE 379.1 Scleritis and episcleritis Both 4 23 7 sense organs darkseagreen4 23, 4 5, 1 6, 1 5, 0 6, 2 0.501 0.728 0.491 0.309 1.65 0.528 44.3 1.78 2.68 0.506 0.295 5.92 0.101 7.74 0.165 5.14 0.974 0.011 1.18 6.01e-06 258000 1.21 2.01 0.549 0.261 3.35 0.0204 33400 PRS_PLINK_0.000199526231496888 TRUE 379.2 Disorders of vitreous body Both 43 118 7 sense organs darkseagreen4 118, 43 30, 9 29, 11 29, 12 30, 11 0.141 0.188 0.452 0.345 1.15 0.803 1.66 0.328 0.597 0.582 0.235 1.39 0.445 4.47 0.299 0.554 0.589 0.23 1.35 0.47 3.95 0.481 0.537 0.371 0.431 1.62 0.589 4.65 PRS_PLINK_0.000199526231496888 TRUE 379.3 Aphakia and other disorders of lens Both 1 5 7 sense organs darkseagreen4 5, 1 2, 1 1, 0 1, 0 1, 0 0.000503 133 1 0 1 0.902 1.13 2.71e-05 4790 1 0 1 0.301 2.53 -6.82e-06 9360 1 0 1 0.13 7.8 -1.34e-05 325 1 0 1 0.923 1.08 PRS_PLINK_0.000199526231496888 TRUE 379.4 Anomalies of pupillary function Both 2 23 7 sense organs darkseagreen4 23, 2 6, 0 6, 0 5, 1 6, 1 1.18 0.972 0.226 0.645 3.24 0.566 48.4 0.703 2.28 0.758 0.12 2.02 0.0522 95.2 -0.823 3.1 0.791 0.102 0.439 0.396 1.23 PRS_PLINK_0.000199526231496888 TRUE 379.5 Disorders of iris and ciliary body Both 4 21 7 sense organs darkseagreen4 21, 4 6, 1 5, 1 5, 1 5, 1 -0.0271 0.563 0.962 0.017 0.973 0.154 2.68 -0.0176 2.46 0.994 0.002 0.983 0.000388 1390 -0.866 2.52 0.731 0.136 0.421 0.00176 15.5 0.114 1.6 0.943 0.025 1.12 0.0846 14.4 PRS_PLINK_0.000199526231496888 TRUE 379.51 Pigmentary iris degeneration Both 2 10 7 sense organs darkseagreen4 10, 2 3, 1 2, 0 2, 1 3, 0 -0.913 1.21 0.45 0.347 0.401 0.0214 2.55 0.189 935 1 0 1.21 0.226 9.01 0.0138 116 1 0 1.01 0.909 1.16 -0.0854 316 1 0 0.918 0.327 1.41 PRS_PLINK_0.000199526231496888 TRUE 379.9 Pain, swelling or discharge of eye Both 22 113 7 sense organs darkseagreen4 113, 22 29, 5 28, 5 28, 7 28, 5 0.15 0.25 0.548 0.261 1.16 0.713 1.95 -0.169 0.713 0.813 0.09 0.845 0.205 3.32 0.415 0.649 0.523 0.282 1.51 0.435 5.52 -0.019 0.693 0.978 0.01 0.981 0.244 3.92 PRS_PLINK_0.000199526231496888 TRUE 380 Disorders of external ear Both 34 147 7 sense organs darkseagreen4 147, 34 37, 15 37, 6 36, 4 37, 9 -0.273 0.201 0.174 0.758 0.761 0.51 1.12 -1.15 0.583 0.0491 1.309 0.317 0.0937 0.927 -0.99 0.623 0.112 0.95 0.371 0.0992 1.18 -0.515 0.51 0.312 0.505 0.598 0.217 1.54 PRS_PLINK_0.000199526231496888 TRUE 380.1 Otitis externa Both 24 135 7 sense organs darkseagreen4 135, 24 34, 8 34, 3 33, 5 34, 8 -0.124 0.211 0.557 0.254 0.883 0.582 1.33 -0.606 0.716 0.398 0.401 0.545 0.114 2.18 -0.267 0.619 0.666 0.176 0.766 0.221 2.54 -0.039 0.587 0.947 0.024 0.962 0.305 2.98 PRS_PLINK_0.000199526231496888 TRUE 380.4 Impacted cerumen Both 43 163 7 sense organs darkseagreen4 163, 43 41, 16 41, 8 40, 8 41, 11 -0.19 0.189 0.315 0.501 0.827 0.569 1.19 -0.958 0.541 0.0769 1.114 0.384 0.127 1.05 -0.566 0.509 0.266 0.575 0.568 0.206 1.48 -0.357 0.491 0.467 0.331 0.7 0.266 1.76 PRS_PLINK_0.000199526231496888 TRUE 381 Otitis media and Eustachian tube disorders Both 93 329 7 sense organs darkseagreen4 329, 93 83, 27 82, 15 82, 23 82, 27 -0.00881 0.122 0.943 0.026 0.991 0.781 1.26 -0.708 0.384 0.0653 1.185 0.493 0.229 1.03 -0.324 0.342 0.344 0.464 0.723 0.37 1.4 -0.0429 0.34 0.899 0.046 0.958 0.494 1.85 PRS_PLINK_0.000199526231496888 FALSE 381.1 Otitis media Both 73 294 7 sense organs darkseagreen4 294, 73 74, 24 73, 11 73, 18 74, 20 -0.0685 0.138 0.621 0.207 0.934 0.711 1.22 -0.917 0.423 0.0303 1.518 0.4 0.17 0.894 -0.388 0.373 0.298 0.526 0.678 0.326 1.39 -0.261 0.374 0.485 0.314 0.77 0.37 1.59 PRS_PLINK_0.000199526231496888 FALSE 381.11 Suppurative and unspecified otitis media Both 60 258 7 sense organs darkseagreen4 258, 60 65, 19 64, 13 64, 12 65, 16 -0.0972 0.148 0.512 0.291 0.907 0.679 1.21 -0.375 0.434 0.387 0.413 0.687 0.29 1.59 -0.529 0.436 0.225 0.648 0.589 0.248 1.36 -0.215 0.408 0.599 0.223 0.807 0.361 1.78 PRS_PLINK_0.000199526231496888 FALSE 381.2 Eustachian tube disorders Both 37 179 7 sense organs darkseagreen4 179, 37 45, 9 45, 3 44, 12 45, 12 0.0138 0.181 0.939 0.027 1.01 0.71 1.45 -0.784 0.628 0.212 0.674 0.457 0.11 1.57 0.215 0.496 0.665 0.177 1.24 0.465 3.36 0.189 0.519 0.716 0.145 1.21 0.435 3.35 PRS_PLINK_0.000199526231496888 TRUE 381.3 Mastoiditis & related conditions Both 1 10 7 sense organs darkseagreen4 10, 1 3, 0 2, 0 2, 0 3, 1 0.71 1.21 0.558 0.253 2.03 0.158 24.2 0.0162 626 1 0 1.02 0.337 2.54 PRS_PLINK_0.000199526231496888 TRUE 381.9 Otorrhea Both 4 25 7 sense organs darkseagreen4 25, 4 7, 2 6, 0 6, 0 6, 2 -0.452 0.728 0.534 0.272 0.636 0.126 2.31 -0.103 2.92 0.972 0.012 0.902 2.72e-07 9540 -0.497 2.93 0.865 0.063 0.608 8.54e-05 192 0.613 1.45 0.673 0.172 1.85 0.113 2510 PRS_PLINK_0.000199526231496888 TRUE 382 Otalgia Both 44 212 7 sense organs darkseagreen4 212, 44 53, 9 53, 17 53, 7 53, 11 -0.0571 0.173 0.742 0.13 0.944 0.671 1.33 0.65 0.454 0.153 0.816 1.91 0.802 4.8 -0.337 0.53 0.525 0.28 0.714 0.241 2.04 0.0297 0.52 0.954 0.02 1.03 0.365 2.92 PRS_PLINK_0.000199526231496888 TRUE 383 Otosclerosis Both 1 12 7 sense organs darkseagreen4 12, 1 3, 0 3, 0 3, 1 3, 0 0.301 1.17 0.796 0.099 1.35 0.0203 24.2 0.149 43200000 1 0 1.16 0.0778 20.4 PRS_PLINK_0.000199526231496888 TRUE 384 Other disorders of tympanic membrane Both 8 34 7 sense organs darkseagreen4 34, 8 9, 2 8, 3 8, 0 9, 3 -0.389 0.446 0.383 0.416 0.678 0.278 1.51 0.606 1.22 0.618 0.209 1.83 0.232 18.3 -2.05 1.67 0.219 0.659 0.129 7.96e-05 1.94 0.133 1.19 0.911 0.04 1.14 0.135 9.38 PRS_PLINK_0.000199526231496888 TRUE 384.1 Myringitis Both 0 4 7 sense organs darkseagreen4 4, 0 1 1 1 1 PRS_PLINK_0.000199526231496888 TRUE 384.4 Perforation of tympanic membrane Both 5 33 7 sense organs darkseagreen4 33, 5 9, 2 8, 1 8, 1 8, 1 -1.03 0.615 0.0943 1.025 0.357 0.0717 1.06 -0.413 1.34 0.759 0.12 0.662 0.0199 18.9 -0.462 1.2 0.7 0.155 0.63 0.0336 4.97 -0.972 1.4 0.487 0.313 0.378 0.0146 3.79 PRS_PLINK_0.000199526231496888 TRUE 385 Other disorders of middle ear and mastoid Both 2 40 7 sense organs darkseagreen4 40, 2 10, 0 10, 0 10, 1 10, 1 1.23 0.867 0.155 0.808 3.43 0.615 2850 0.541 1.47 0.713 0.147 1.72 0.0835 225 2.66 2.35 0.257 0.59 14.4 0.274 20400 PRS_PLINK_0.000199526231496888 TRUE 385.3 Cholesteatoma Both 0 25 7 sense organs darkseagreen4 25, 0 7 6 6 6 PRS_PLINK_0.000199526231496888 TRUE 385.5 Tympanosclerosis and middle ear disease related to otitis media Both 1 11 7 sense organs darkseagreen4 11, 1 3, 0 3, 0 2, 0 3, 1 0.829 1.1 0.452 0.345 2.29 0.303 37.7 -0.26 14 0.985 0.006 0.771 0.501 0.415 PRS_PLINK_0.000199526231496888 TRUE 386 Vertiginous syndromes and other disorders of vestibular system Both 30 144 7 sense organs darkseagreen4 144, 30 35, 5 36, 7 36, 11 36, 7 0.0614 0.204 0.763 0.117 1.06 0.715 1.6 0.35 0.635 0.581 0.236 1.42 0.405 5.12 0.724 0.588 0.219 0.66 2.06 0.671 6.98 0.425 0.673 0.527 0.278 1.53 0.402 6.07 PRS_PLINK_0.000199526231496888 TRUE 386.1 Meniere's disease Both 4 22 7 sense organs darkseagreen4 22, 4 6, 1 5, 1 5, 1 6, 1 -0.483 0.607 0.427 0.37 0.617 0.0937 1.83 0.117 2.56 0.963 0.016 1.12 0.001 59.3 -0.857 2.76 0.756 0.121 0.425 0.000126 27 2.03 3.61 0.574 0.241 7.59 0.0236 23900 PRS_PLINK_0.000199526231496888 TRUE 386.2 Peripheral or central vertigo Both 24 102 7 sense organs darkseagreen4 102, 24 25, 4 25, 9 25, 8 26, 3 0.00135 0.222 0.995 0.002 1 0.652 1.56 0.762 0.682 0.264 0.579 2.14 0.59 8.6 0.824 0.708 0.244 0.612 2.28 0.607 9.57 -0.341 0.854 0.69 0.161 0.711 0.118 3.85 PRS_PLINK_0.000199526231496888 TRUE 386.21 Central origin vertigo Both 13 81 7 sense organs darkseagreen4 81, 13 20, 1 20, 9 20, 3 20, 0 -0.131 0.333 0.694 0.159 0.877 0.447 1.76 1.51 0.971 0.119 0.923 4.54 0.753 49.7 0.417 1.18 0.724 0.14 1.52 0.119 21.9 -1.26 1.41 0.373 0.428 0.285 0.000317 5.35 PRS_PLINK_0.000199526231496888 TRUE 386.3 Labyrinthitis Both 17 109 7 sense organs darkseagreen4 109, 17 27, 2 27, 5 27, 7 27, 3 -0.137 0.284 0.63 0.201 0.872 0.485 1.57 0.682 0.852 0.423 0.373 1.98 0.326 13 0.318 0.884 0.719 0.143 1.37 0.226 9.72 0.142 0.993 0.886 0.052 1.15 0.135 8.42 PRS_PLINK_0.000199526231496888 TRUE 386.9 Dizziness and giddiness (Light-headedness and vertigo) Both 121 326 7 sense organs darkseagreen4 326, 121 81, 26 81, 28 81, 39 82, 28 0.0301 0.112 0.787 0.104 1.03 0.829 1.28 0.182 0.333 0.585 0.233 1.2 0.63 2.3 0.295 0.32 0.356 0.449 1.34 0.727 2.51 0.175 0.338 0.605 0.218 1.19 0.62 2.3 PRS_PLINK_0.000199526231496888 FALSE 388 Other disorders of ear Both 16 84 7 sense organs darkseagreen4 84, 16 21, 4 21, 4 21, 2 21, 6 0.000554 0.293 0.998 0.001 1 0.564 1.77 0.129 0.735 0.86 0.065 1.14 0.27 4.95 -0.929 0.972 0.34 0.469 0.395 0.0417 2.57 -0.182 0.78 0.816 0.089 0.834 0.178 3.87 PRS_PLINK_0.000199526231496888 TRUE 389 Hearing loss Both 100 345 7 sense organs darkseagreen4 345, 100 86, 22 86, 36 86, 14 86, 28 -0.0906 0.122 0.457 0.34 0.913 0.72 1.16 0.638 0.338 0.059 1.229 1.89 0.993 3.69 -0.629 0.427 0.14 0.854 0.533 0.225 1.2 0.296 0.364 0.416 0.381 1.34 0.666 2.74 PRS_PLINK_0.000199526231496888 FALSE 389.1 Sensorineural hearing loss Both 47 192 7 sense organs darkseagreen4 192, 47 47, 11 48, 16 48, 9 48, 11 -0.0643 0.182 0.725 0.14 0.938 0.657 1.34 0.533 0.475 0.261 0.583 1.7 0.696 4.34 -0.537 0.578 0.353 0.452 0.585 0.181 1.76 0.0743 0.513 0.885 0.053 1.08 0.4 2.91 PRS_PLINK_0.000199526231496888 TRUE 389.2 Conductive hearing loss Both 8 102 7 sense organs darkseagreen4 102, 8 26, 1 25, 3 25, 1 26, 3 0.27 0.33 0.413 0.384 1.31 0.642 2.78 0.963 0.931 0.301 0.522 2.62 0.429 23 -0.363 1.05 0.729 0.137 0.696 0.0279 7.89 0.901 0.954 0.345 0.462 2.46 0.336 25.6 PRS_PLINK_0.000199526231496888 TRUE 389.3 Degenerative and vascular disorders of ear Both 1 15 7 sense organs darkseagreen4 15, 1 4, 0 4, 0 3, 0 4, 1 0.0603 0.871 0.945 0.025 1.06 0.194 9.41 0.156 49.2 0.997 0.001 1.17 14.2 14.9 PRS_PLINK_0.000199526231496888 TRUE 389.4 Tinnitus Both 44 156 7 sense organs darkseagreen4 156, 44 38, 7 39, 20 39, 8 39, 9 -0.31 0.186 0.0957 1.019 0.733 0.508 1.05 0.848 0.52 0.103 0.988 2.34 0.891 6.63 -0.238 0.632 0.706 0.151 0.788 0.223 2.75 -0.189 0.623 0.761 0.119 0.827 0.239 2.79 PRS_PLINK_0.000199526231496888 TRUE 389.5 Disorders of acoustic nerve Both 1 15 7 sense organs darkseagreen4 15, 1 4, 0 4, 0 3, 0 4, 1 -0.0983 0.786 0.9 0.046 0.906 0.0858 6.64 1.32 153 0.993 0.003 3.74 3.43 4.08 PRS_PLINK_0.000199526231496888 TRUE 394 Rheumatic disease of the heart valves Both 7 70 8 circulatory system red 70, 7 18, 0 17, 3 17, 4 18, 0 -0.0129 0.378 0.973 0.012 0.987 0.461 2.25 2.15 1.38 0.118 0.928 8.62 0.646 3700 1.51 1.28 0.24 0.621 4.52 0.359 537 PRS_PLINK_0.000199526231496888 TRUE 394.1 Mitral valve stenosis and aortic valve stenosis Both 4 9 8 circulatory system red 9, 4 3, 0 2, 1 2, 1 2, 2 -0.1 1.45 0.945 0.025 0.904 0.0818 17.2 0.102 388 1 0 1.11 0.7 1.72 -0.0504 205 1 0 0.951 0.841 1.09 0.356 2080 1 0 1.43 0.219 26.2 PRS_PLINK_0.000199526231496888 TRUE 394.2 Mitral valve disease Both 3 22 8 circulatory system red 22, 3 6, 0 5, 2 5, 1 6, 0 0.153 0.979 0.876 0.057 1.16 0.135 17.8 0.629 1.87 0.737 0.133 1.88 0.0617 113 1.33 3.94 0.736 0.133 3.78 0.00386 10900 PRS_PLINK_0.000199526231496888 TRUE 394.3 Aortic valve disease Both 0 7 8 circulatory system red 7, 0 2 2 1 2 PRS_PLINK_0.000199526231496888 TRUE 394.4 Acute rheumatic heart disease Both 2 6 8 circulatory system red 6, 2 2, 0 1, 1 1, 1 2, 0 0.193 3.17 0.951 0.022 1.21 0.0135 210 -0.256 11400 1 0 0.774 0.664 3.01 -0.916 24600000 1 0 0.4 0.00232 28.4 PRS_PLINK_0.000199526231496888 TRUE 394.7 Disease of tricuspid valve Both 2 26 8 circulatory system red 26, 2 7, 0 6, 2 6, 0 7, 0 0.105 0.643 0.871 0.06 1.11 0.303 11.8 1.23 2.08 0.553 0.257 3.44 0.186 1020 PRS_PLINK_0.000199526231496888 TRUE 395 Heart valve disorders Both 27 187 8 circulatory system red 187, 27 47, 3 47, 11 46, 6 47, 7 0.241 0.214 0.261 0.583 1.27 0.841 1.96 1.76 0.749 0.0187 1.729 5.83 1.5 31.4 1.13 0.795 0.156 0.807 3.09 0.662 20.8 1.25 0.75 0.0968 1.014 3.47 0.862 19.6 PRS_PLINK_0.000199526231496888 TRUE 395.1 Nonrheumatic mitral valve disorders Both 16 138 8 circulatory system red 138, 16 35, 4 34, 5 34, 2 35, 5 0.221 0.268 0.41 0.388 1.25 0.741 2.19 0.278 0.733 0.704 0.152 1.32 0.303 6.2 -0.571 0.818 0.485 0.314 0.565 0.0765 2.93 0.636 0.723 0.379 0.421 1.89 0.452 8.87 PRS_PLINK_0.000199526231496888 TRUE 395.2 Nonrheumatic aortic valve disorders Both 11 75 8 circulatory system red 75, 11 19, 1 19, 5 18, 4 19, 1 0.125 0.357 0.727 0.138 1.13 0.555 2.35 2.86 1.66 0.0846 1.073 17.5 0.947 13500 1.56 1.13 0.17 0.77 4.74 0.587 343 0.102 1.18 0.932 0.031 1.11 0.0591 40.8 PRS_PLINK_0.000199526231496888 TRUE 395.3 Nonrheumatic tricuspid valve disorders Both 2 22 8 circulatory system red 22, 2 6, 0 5, 1 5, 0 6, 1 0.076 0.728 0.917 0.038 1.08 0.103 7.74 -0.742 2.72 0.785 0.105 0.476 0.00143 96.8 -0.209 2.35 0.929 0.032 0.811 0.000568 260 PRS_PLINK_0.000199526231496888 TRUE 395.4 Nonrheumatic pulmonary valve disorders Both 1 10 8 circulatory system red 10, 1 3, 0 2, 0 2, 0 3, 1 0.39 2.36 0.869 0.061 1.48 0.0104 1280 1.83 56.5 0.974 0.011 6.26 0.257 16.8 PRS_PLINK_0.000199526231496888 TRUE 395.6 Heart valve replaced Both 6 48 8 circulatory system red 48, 6 12, 0 12, 3 12, 1 12, 2 0.406 0.424 0.339 0.47 1.5 0.648 4.06 0.641 1.24 0.606 0.218 1.9 0.162 35.4 1.06 1.44 0.463 0.334 2.88 0.164 1210 1.11 1.26 0.378 0.422 3.04 0.256 695 PRS_PLINK_0.000199526231496888 TRUE 396 Abnormal heart sounds Both 53 329 8 circulatory system red 329, 53 82, 16 82, 12 82, 18 82, 7 -0.209 0.151 0.168 0.775 0.812 0.602 1.09 -0.117 0.428 0.784 0.106 0.889 0.381 2.04 0.168 0.391 0.668 0.175 1.18 0.551 2.57 -0.877 0.496 0.0771 1.113 0.416 0.147 1.07 PRS_PLINK_0.000199526231496888 FALSE 401 Hypertension Both 184 268 8 circulatory system red 268, 184 66, 59 67, 39 67, 52 67, 34 -0.0617 0.109 0.573 0.242 0.94 0.759 1.16 -0.186 0.3 0.535 0.272 0.83 0.463 1.49 0.00719 0.29 0.98 0.009 1.01 0.575 1.77 -0.45 0.312 0.149 0.827 0.637 0.348 1.16 PRS_PLINK_0.000199526231496888 FALSE 401.1 Essential hypertension Both 180 268 8 circulatory system red 268, 180 66, 58 67, 38 67, 51 67, 33 -0.0705 0.112 0.527 0.278 0.932 0.75 1.16 -0.175 0.301 0.56 0.251 0.839 0.467 1.51 0.00466 0.293 0.987 0.006 1 0.57 1.78 -0.471 0.316 0.136 0.867 0.624 0.338 1.14 PRS_PLINK_0.000199526231496888 FALSE 401.2 Hypertensive heart and/or renal disease Both 44 89 8 circulatory system red 89, 44 23, 12 22, 10 22, 13 22, 9 0.0976 0.201 0.628 0.202 1.1 0.754 1.63 -0.396 0.626 0.527 0.278 0.673 0.195 2.16 0.435 0.6 0.468 0.33 1.54 0.508 4.95 0.0473 0.629 0.94 0.027 1.05 0.314 3.48 PRS_PLINK_0.000199526231496888 TRUE 401.21 Hypertensive heart disease Both 8 37 8 circulatory system red 37, 8 10, 2 9, 2 9, 1 9, 3 -0.155 0.429 0.718 0.144 0.857 0.805 2.08 0.522 1.39 0.707 0.15 1.69 0.0587 759 -0.635 1.59 0.689 0.162 0.53 0.00437 102 0.438 1.52 0.773 0.112 1.55 0.00722 121 PRS_PLINK_0.000199526231496888 TRUE 401.22 Hypertensive chronic kidney disease Both 39 70 8 circulatory system red 70, 39 18, 11 17, 9 17, 12 18, 7 0.158 0.229 0.491 0.309 1.17 0.763 1.83 -0.315 0.657 0.631 0.2 0.73 0.204 2.46 0.629 0.667 0.346 0.461 1.88 0.558 7.04 0.0485 0.72 0.946 0.024 1.05 0.279 4.18 PRS_PLINK_0.000199526231496888 TRUE 401.3 Other hypertensive complications Both 63 124 8 circulatory system red 124, 63 31, 17 31, 15 31, 18 31, 13 0.153 0.179 0.393 0.406 1.17 0.827 1.65 0.333 0.498 0.503 0.298 1.4 0.548 3.67 0.622 0.523 0.234 0.63 1.86 0.708 5.23 0.236 0.521 0.65 0.187 1.27 0.473 3.48 PRS_PLINK_0.000199526231496888 FALSE 411 Ischemic Heart Disease Both 47 242 8 circulatory system red 242, 47 61, 12 60, 9 60, 12 61, 14 0.161 0.183 0.379 0.422 1.17 0.822 1.69 -0.193 0.503 0.701 0.154 0.824 0.305 2.2 0.0393 0.498 0.937 0.028 1.04 0.389 2.77 0.324 0.528 0.539 0.268 1.38 0.495 3.95 PRS_PLINK_0.000199526231496888 TRUE 411.1 Unstable angina (intermediate coronary syndrome) Both 7 32 8 circulatory system red 32, 7 8, 2 8, 2 8, 1 8, 2 0.204 0.562 0.716 0.145 1.23 0.449 4.02 0.34 1.45 0.814 0.089 1.4 0.000484 3210 -0.542 1.49 0.716 0.145 0.582 0.00558 6.32 0.874 1.32 0.508 0.294 2.4 0.298 78.6 PRS_PLINK_0.000199526231496888 TRUE 411.2 Myocardial infarction Both 16 115 8 circulatory system red 115, 16 29, 3 29, 4 28, 3 29, 6 0.343 0.291 0.239 0.622 1.41 0.793 2.59 0.078 0.774 0.92 0.036 1.08 0.219 5.39 0.00449 0.828 0.996 0.002 1 0.164 5.69 0.369 0.821 0.653 0.185 1.45 0.28 8.58 PRS_PLINK_0.000199526231496888 TRUE 411.3 Angina pectoris Both 15 104 8 circulatory system red 104, 15 26, 3 26, 4 26, 2 26, 6 0.356 0.293 0.225 0.648 1.43 0.805 2.68 0.727 0.951 0.445 0.352 2.07 0.324 18.7 -0.335 0.901 0.71 0.149 0.715 0.074 4.54 3.77 1.95 0.0525 1.28 43.6 1.61 4.39e+10 PRS_PLINK_0.000199526231496888 TRUE 411.4 Coronary atherosclerosis Both 38 184 8 circulatory system red 184, 38 46, 11 46, 7 46, 10 46, 10 0.0334 0.204 0.87 0.061 1.03 0.693 1.54 -0.341 0.541 0.529 0.276 0.711 0.243 2 -0.107 0.522 0.837 0.077 0.898 0.321 2.47 0.0261 0.594 0.965 0.015 1.03 0.317 3.28 PRS_PLINK_0.000199526231496888 TRUE 411.41 Aneurysm and dissection of heart Both 0 6 8 circulatory system red 6, 0 2 1 1 2 PRS_PLINK_0.000199526231496888 TRUE 411.8 Other chronic ischemic heart disease, unspecified Both 24 158 8 circulatory system red 158, 24 40, 8 39, 5 39, 4 40, 7 -0.0144 0.243 0.953 0.021 0.986 0.608 1.6 -0.489 0.608 0.42 0.376 0.613 0.176 1.97 -0.971 0.704 0.168 0.776 0.379 0.0803 1.44 0.0557 0.67 0.934 0.03 1.06 0.274 4.03 PRS_PLINK_0.000199526231496888 TRUE 411.9 Other acute and subacute forms of ischemic heart disease Both 5 18 8 circulatory system red 18, 5 5, 1 4, 2 4, 0 5, 2 -0.00253 0.629 0.997 0.001 0.997 0.223 3.33 3.56 4.32 0.409 0.388 35.3 0.117 90500 -2.63 5.87 0.654 0.185 0.0719 6.69e-06 529 -0.901 2.09 0.666 0.177 0.406 0.00062 564 PRS_PLINK_0.000199526231496888 TRUE 414 Other forms of chronic heart disease Both 24 155 8 circulatory system red 155, 24 39, 6 39, 5 38, 7 39, 6 0.0158 0.234 0.946 0.024 1.02 0.641 1.62 -0.168 0.622 0.787 0.104 0.845 0.238 2.92 -0.144 0.632 0.819 0.087 0.865 0.242 3.06 -0.0527 0.759 0.945 0.025 0.949 0.188 4.36 PRS_PLINK_0.000199526231496888 TRUE 414.2 ASCVD Both 9 48 8 circulatory system red 48, 9 12, 2 12, 1 12, 2 12, 4 -0.0463 0.361 0.898 0.047 0.955 0.467 1.95 -0.693 1.35 0.608 0.216 0.5 0.0269 7.64 0.248 1.17 0.832 0.08 1.28 0.0835 12.6 0.457 1.1 0.679 0.168 1.58 0.125 79.6 PRS_PLINK_0.000199526231496888 TRUE 415 Pulmonary heart disease Both 28 209 8 circulatory system red 209, 28 53, 8 52, 11 52, 7 52, 2 -0.127 0.201 0.527 0.278 0.881 0.586 1.32 0.361 0.485 0.457 0.34 1.43 0.551 3.89 -0.268 0.565 0.635 0.197 0.765 0.237 2.37 -1.03 0.66 0.119 0.925 0.357 0.0694 1.29 PRS_PLINK_0.000199526231496888 TRUE 415.1 Acute pulmonary heart disease Both 21 137 8 circulatory system red 137, 21 35, 6 34, 8 34, 6 34, 1 -0.11 0.238 0.643 0.192 0.895 0.555 1.45 0.196 0.575 0.733 0.135 1.22 0.394 3.95 0.0519 0.604 0.932 0.031 1.05 0.314 3.53 -1.1 0.835 0.186 0.73 0.332 0.0352 1.63 PRS_PLINK_0.000199526231496888 TRUE 415.11 Pulmonary embolism and infarction, acute Both 21 136 8 circulatory system red 136, 21 34, 6 34, 8 34, 6 34, 1 -0.113 0.239 0.636 0.197 0.893 0.554 1.45 0.19 0.579 0.743 0.129 1.21 0.388 4.03 0.00681 0.608 0.991 0.004 1.01 0.298 3.38 -1.16 0.835 0.164 0.785 0.313 0.0332 1.54 PRS_PLINK_0.000199526231496888 TRUE 415.2 Chronic pulmonary heart disease Both 13 104 8 circulatory system red 104, 13 26, 4 26, 5 26, 3 26, 1 -0.0211 0.295 0.943 0.025 0.979 0.53 1.8 0.0154 0.697 0.982 0.008 1.02 0.252 4.21 -0.538 0.884 0.543 0.265 0.584 0.0675 3.55 -0.964 0.914 0.292 0.535 0.381 0.0327 2.39 PRS_PLINK_0.000199526231496888 TRUE 415.21 Primary pulmonary hypertension Both 5 43 8 circulatory system red 43, 5 11, 0 11, 3 10, 2 11, 0 -0.00378 0.512 0.994 0.003 0.996 0.294 2.82 1.01 1.25 0.421 0.375 2.74 0.229 165 1.61 1.63 0.324 0.49 4.98 0.304 59700 PRS_PLINK_0.000199526231496888 TRUE 416 Cardiomegaly Both 15 76 8 circulatory system red 76, 15 19, 5 19, 2 19, 5 19, 3 -0.089 0.31 0.774 0.111 0.915 0.497 1.66 -0.469 0.806 0.561 0.251 0.626 0.109 2.96 -0.245 0.775 0.752 0.124 0.782 0.166 3.51 -0.398 0.932 0.669 0.174 0.672 0.069 4.01 PRS_PLINK_0.000199526231496888 TRUE 418 Nonspecific chest pain Both 194 255 8 circulatory system red 255, 194 63, 47 64, 46 63, 50 64, 51 0.0723 0.104 0.487 0.313 1.07 0.879 1.32 0.109 0.303 0.72 0.143 1.11 0.622 2 0.175 0.306 0.567 0.246 1.19 0.661 2.16 0.0709 0.301 0.814 0.089 1.07 0.601 1.92 PRS_PLINK_0.000199526231496888 FALSE 418.1 Precordial pain Both 25 69 8 circulatory system red 69, 25 18, 6 17, 7 17, 6 17, 6 -0.224 0.266 0.4 0.398 0.799 0.477 1.31 0.029 0.761 0.97 0.013 1.03 0.225 4.36 0.0775 0.702 0.912 0.04 1.08 0.288 4.07 -0.347 0.748 0.643 0.192 0.707 0.165 2.76 PRS_PLINK_0.000199526231496888 TRUE 420 Carditis Both 12 106 8 circulatory system red 106, 12 27, 1 26, 1 26, 7 27, 3 0.404 0.336 0.229 0.641 1.5 0.758 3.04 0.113 0.926 0.902 0.045 1.12 0.112 11.3 1.32 0.946 0.163 0.788 3.74 0.643 40.3 0.969 1.07 0.365 0.438 2.64 0.282 43.2 PRS_PLINK_0.000199526231496888 TRUE 420.1 Myocarditis Both 0 4 8 circulatory system red 4, 0 1 1 1 1 PRS_PLINK_0.000199526231496888 TRUE 420.2 Pericarditis Both 7 59 8 circulatory system red 59, 7 15, 0 15, 1 14, 5 15, 1 0.322 0.399 0.419 0.378 1.38 0.617 3.21 0.898 1.23 0.465 0.332 2.46 0.2 159 2.73 1.88 0.145 0.838 15.4 0.639 95000 0.887 1.25 0.477 0.321 2.43 0.11 879 PRS_PLINK_0.000199526231496888 TRUE 420.21 Acute pericarditis Both 1 12 8 circulatory system red 12, 1 3, 0 3, 0 3, 1 3, 0 0.0353 3.7 0.992 0.003 1.04 4.69e-05 10300 0.0192 434 1 0 1.02 0.143 39.8 PRS_PLINK_0.000199526231496888 TRUE 420.22 Chronic pericarditis Both 1 7 8 circulatory system red 7, 1 2, 0 2, 1 1, 0 2, 0 0.029 97.8 1 0 1.03 0.888 3.07 -0.0238 157 1 0 0.977 0.464 1.95 PRS_PLINK_0.000199526231496888 TRUE 420.3 Endocarditis Both 6 55 8 circulatory system red 55, 6 14, 1 14, 1 13, 3 14, 1 0.201 0.466 0.666 0.176 1.22 0.431 3.78 -0.325 1.14 0.776 0.11 0.722 0.0318 17.3 0.319 1.24 0.796 0.099 1.38 0.115 29.8 -0.344 1.09 0.752 0.124 0.709 0.00962 7.54 PRS_PLINK_0.000199526231496888 TRUE 425 Cardiomyopathy Both 13 114 8 circulatory system red 114, 13 29, 1 28, 5 28, 2 29, 5 0.429 0.32 0.18 0.744 1.54 0.812 3.05 1.98 1.28 0.122 0.912 7.24 0.654 794 -0.0682 1.04 0.948 0.023 0.934 0.0564 15.2 1.82 1.2 0.13 0.885 6.18 0.648 290 PRS_PLINK_0.000199526231496888 TRUE 425.1 Primary/intrinsic cardiomyopathies Both 12 107 8 circulatory system red 107, 12 27, 1 27, 5 26, 2 27, 4 0.336 0.327 0.303 0.518 1.4 0.725 2.82 1.85 1.24 0.137 0.864 6.34 0.607 704 0.149 1.02 0.884 0.054 1.16 0.0681 19.1 1.62 1.18 0.172 0.765 5.04 0.532 167 PRS_PLINK_0.000199526231496888 TRUE 425.11 Hypertrophic obstructive cardiomyopathy Both 3 8 8 circulatory system red 8, 3 2, 2 2, 0 2, 0 2, 1 1.12 1.52 0.463 0.335 3.06 0.368 53.8 -0.65 7470 1 0 0.522 0.0301 7.01 -0.315 4240 1 0 0.73 0.544 3.07 -0.168 2390 1 0 0.845 0.745 1.49 PRS_PLINK_0.000199526231496888 TRUE 425.12 Other hypertrophic cardiomyopathy Both 2 11 8 circulatory system red 11, 2 3, 1 3, 0 2, 0 3, 1 0.539 1.3 0.677 0.169 1.71 0.182 15.4 0.0733 576 1 0 1.08 0.548 2.56 0.011 155 1 0 1.01 0.862 1.18 -1.44 58.5 0.98 0.009 0.236 1.85e-10 0.328 PRS_PLINK_0.000199526231496888 TRUE 425.2 Secondary/extrinsic cardiomyopathies Both 3 21 8 circulatory system red 21, 3 6, 1 5, 1 5, 0 5, 1 -0.05 0.638 0.938 0.028 0.951 0.255 3.06 1.5 2.24 0.505 0.297 4.46 0.0838 8.17e+08 0.399 1.68 0.812 0.09 1.49 0.0752 103 1.18 2.76 0.67 0.174 3.24 0.0526 4490000 PRS_PLINK_0.000199526231496888 TRUE 425.8 Other cardiomyopathy Both 2 7 8 circulatory system red 7, 2 2, 0 2, 0 1, 1 2, 1 0.428 4.58 0.926 0.034 1.53 0.322 2.15 0.264 5820 1 0 1.3 0.578 1.66 -0.0115 3300 1 0 0.989 0.375 1.64 PRS_PLINK_0.000199526231496888 TRUE 426 Cardiac conduction disorders Both 129 214 8 circulatory system red 214, 129 53, 32 53, 33 53, 32 54, 32 0.155 0.132 0.242 0.617 1.17 0.905 1.51 0.486 0.365 0.182 0.739 1.63 0.811 3.34 0.22 0.364 0.545 0.263 1.25 0.623 2.53 0.353 0.389 0.365 0.438 1.42 0.678 3.07 PRS_PLINK_0.000199526231496888 FALSE 426.2 Atrioventricular [AV] block Both 14 33 8 circulatory system red 33, 14 9, 3 8, 4 8, 4 8, 3 -0.0264 0.411 0.949 0.023 0.974 0.44 2.03 -0.644 1.39 0.642 0.192 0.525 0.0298 5.73 1.51 1.69 0.372 0.429 4.51 0.256 476 -0.721 1.51 0.632 0.199 0.486 0.00171 20.9 PRS_PLINK_0.000199526231496888 TRUE 426.21 First degree AV block Both 8 25 8 circulatory system red 25, 8 7, 3 6, 0 6, 3 6, 2 -0.127 0.552 0.819 0.087 0.881 0.314 2.39 0.235 2.22 0.916 0.038 1.26 0.00196 209 -0.323 1.21 0.79 0.102 0.724 0.0882 5.2 0.0503 1.46 0.972 0.012 1.05 0.00137 33.3 PRS_PLINK_0.000199526231496888 TRUE 426.23 Second degree AV block Both 0 7 8 circulatory system red 7, 0 2 2 1 2 PRS_PLINK_0.000199526231496888 TRUE 426.24 Atrioventricular block, complete Both 3 8 8 circulatory system red 8, 3 2, 0 2, 0 2, 2 2, 1 0.873 2.4 0.716 0.145 2.4 0.0665 77.8 0.353 7480 1 0 1.42 0.0528 1.67 -0.451 9410 1 0 0.637 0.554 3.66 PRS_PLINK_0.000199526231496888 TRUE 426.25 Other heart block Both 2 2 8 circulatory system red 2, 2 1, 0 0, 1 1, 1 1, 0 0.05 4500 1 0 1.05 0.823 1.21 -0.00194 85.8 1 0 0.998 0.972 1.08 -0.013 121 1 0 0.987 0.936 1.06 PRS_PLINK_0.000199526231496888 TRUE 426.3 Bundle branch block Both 14 57 8 circulatory system red 57, 14 15, 4 14, 3 14, 2 14, 5 0.227 0.333 0.496 0.305 1.25 0.673 2.43 0.228 0.904 0.801 0.096 1.26 0.218 7.35 -0.221 1.21 0.855 0.068 0.802 0.0559 1.05 0.589 0.934 0.528 0.277 1.8 0.342 11.7 PRS_PLINK_0.000199526231496888 TRUE 426.31 Right bundle branch block Both 9 37 8 circulatory system red 37, 9 10, 2 9, 2 9, 1 9, 4 0.471 0.475 0.321 0.493 1.6 0.675 4.26 0.812 1.28 0.527 0.278 2.25 0.223 2.73 -0.309 1.66 0.852 0.069 0.734 0.00301 61.4 1.21 1.51 0.422 0.375 3.36 0.265 2570 PRS_PLINK_0.000199526231496888 TRUE 426.32 Left bundle branch block Both 5 29 8 circulatory system red 29, 5 8, 2 7, 0 7, 2 7, 1 0.37 0.814 0.649 0.187 1.45 0.21 11.4 -0.952 2.02 0.638 0.195 0.386 0.00267 36 0.164 1.56 0.917 0.038 1.18 0.046 30.3 -0.0972 2.3 0.966 0.015 0.907 5.51e-05 89.8 PRS_PLINK_0.000199526231496888 TRUE 426.4 Anomalous atrioventricular excitation Both 0 6 8 circulatory system red 6, 0 2 1 1 2 PRS_PLINK_0.000199526231496888 TRUE 426.7 Abnormal electrocardiogram [ECG] [EKG] Both 120 214 8 circulatory system red 214, 120 53, 29 53, 28 53, 31 54, 32 0.229 0.137 0.0945 1.024 1.26 0.966 1.65 0.509 0.389 0.191 0.72 1.66 0.791 3.61 0.377 0.38 0.32 0.494 1.46 0.709 3.08 0.559 0.407 0.17 0.77 1.75 0.808 3.95 PRS_PLINK_0.000199526231496888 FALSE 426.8 Other cardiac conduction disorders Both 8 44 8 circulatory system red 44, 8 11, 4 11, 1 11, 2 11, 1 -0.422 0.415 0.309 0.511 0.656 0.287 1.39 -0.614 1.05 0.559 0.253 0.541 0.0564 3.84 -0.196 0.972 0.84 0.076 0.822 0.123 5.59 -0.536 1.13 0.636 0.197 0.585 0.0334 4.57 PRS_PLINK_0.000199526231496888 TRUE 426.9 Cardiac pacemaker/device in situ Both 9 41 8 circulatory system red 41, 9 11, 0 10, 3 10, 4 10, 2 0.252 0.502 0.616 0.21 1.29 0.47 3.47 2.43 1.81 0.179 0.747 11.4 0.546 93700000 1.38 1.62 0.396 0.402 3.96 0.244 17400 0.573 1.68 0.733 0.135 1.77 0.0057 2310 PRS_PLINK_0.000199526231496888 TRUE 426.91 Cardiac pacemaker in situ Both 7 25 8 circulatory system red 25, 7 7, 0 6, 1 6, 3 6, 3 0.41 0.622 0.509 0.293 1.51 0.487 6.23 1.1 2.87 0.702 0.154 3 0.0149 33300 -0.196 2.19 0.929 0.032 0.822 0.00629 126 0.758 2.43 0.755 0.122 2.13 0.00224 8240 PRS_PLINK_0.000199526231496888 TRUE 426.92 Cardiac defibrillator in situ Both 4 18 8 circulatory system red 18, 4 5, 0 4, 1 4, 2 5, 1 0.737 0.721 0.307 0.513 2.09 0.587 20.2 1.48 2.33 0.526 0.279 4.38 0.132 232 0.981 5.41 0.856 0.068 2.67 0.000201 222000 0.15 2.75 0.957 0.019 1.16 0.00238 246 PRS_PLINK_0.000199526231496888 TRUE 427 Cardiac dysrhythmias Both 197 216 8 circulatory system red 216, 197 53, 43 54, 46 54, 52 54, 56 0.101 0.109 0.351 0.454 1.11 0.897 1.37 0.203 0.317 0.522 0.282 1.22 0.666 2.26 0.241 0.304 0.428 0.368 1.27 0.712 2.29 0.501 0.311 0.107 0.97 1.65 0.914 3.03 PRS_PLINK_0.000199526231496888 FALSE 427.1 Paroxysmal tachycardia, unspecified Both 27 114 8 circulatory system red 114, 27 29, 5 28, 6 28, 10 29, 6 0.162 0.25 0.515 0.288 1.18 0.731 1.92 0.949 0.762 0.213 0.671 2.58 0.622 14.3 0.901 0.67 0.179 0.748 2.46 0.727 10.2 0.51 0.788 0.517 0.286 1.67 0.389 8.6 PRS_PLINK_0.000199526231496888 TRUE 427.11 Paroxysmal supraventricular tachycardia Both 21 97 8 circulatory system red 97, 21 25, 4 24, 6 24, 5 24, 6 0.0943 0.276 0.733 0.135 1.1 0.647 1.89 0.616 0.745 0.408 0.389 1.85 0.466 9.34 0.265 0.728 0.716 0.145 1.3 0.322 5.81 0.593 0.803 0.46 0.337 1.81 0.41 9.4 PRS_PLINK_0.000199526231496888 TRUE 427.12 Paroxysmal ventricular tachycardia Both 9 39 8 circulatory system red 39, 9 10, 2 10, 1 9, 2 10, 4 0.765 0.632 0.226 0.645 2.15 0.668 8.04 1.32 1.88 0.483 0.316 3.73 0.0527 48300 -0.879 1.78 0.621 0.207 0.415 0.000224 840 1.15 1.6 0.471 0.327 3.17 0.0619 150 PRS_PLINK_0.000199526231496888 TRUE 427.2 Atrial fibrillation and flutter Both 26 87 8 circulatory system red 87, 26 22, 5 22, 7 21, 9 22, 5 0.322 0.302 0.287 0.543 1.38 0.772 2.55 0.955 0.836 0.253 0.597 2.6 0.551 16.6 1 0.772 0.193 0.714 2.73 0.678 14.1 1.43 1.24 0.248 0.606 4.18 0.336 82.2 PRS_PLINK_0.000199526231496888 TRUE 427.21 Atrial fibrillation Both 25 82 8 circulatory system red 82, 25 21, 4 20, 7 20, 9 21, 5 0.369 0.305 0.226 0.647 1.45 0.809 2.69 1.79 1.02 0.0798 1.098 5.96 0.945 91.2 1.28 0.831 0.122 0.913 3.61 0.821 22.7 1.73 1.27 0.172 0.766 5.66 0.413 105 PRS_PLINK_0.000199526231496888 TRUE 427.22 Atrial flutter Both 11 34 8 circulatory system red 34, 11 9, 3 8, 2 8, 4 9, 2 -0.00636 0.453 0.989 0.005 0.994 0.434 2.38 -0.104 1.61 0.948 0.023 0.901 0.0158 44.5 0.691 1.22 0.573 0.242 2 0.245 98.5 -0.836 1.85 0.651 0.187 0.433 0.000404 9.95 PRS_PLINK_0.000199526231496888 TRUE 427.3 Other specified cardiac dysrhythmias Both 101 214 8 circulatory system red 214, 101 53, 22 53, 24 53, 27 54, 28 0.0608 0.136 0.656 0.183 1.06 0.817 1.39 0.375 0.387 0.332 0.479 1.46 0.696 3.09 0.275 0.372 0.459 0.338 1.32 0.649 2.71 0.42 0.39 0.281 0.551 1.52 0.726 3.28 PRS_PLINK_0.000199526231496888 FALSE 427.4 Cardiac arrest and ventricular fibrillation Both 4 19 8 circulatory system red 19, 4 5, 2 5, 1 4, 1 5, 0 -0.355 0.572 0.534 0.272 0.701 0.243 2 -2.72 4.38 0.534 0.272 0.0657 0.0564 25.7 -1.17 1.72 0.496 0.305 0.311 0.011 3.66 -0.981 2.48 0.693 0.159 0.375 0.00649 25.3 PRS_PLINK_0.000199526231496888 TRUE 427.41 Ventricular fibrillation and flutter Both 1 8 8 circulatory system red 8, 1 2, 1 2, 0 2, 0 2, 0 0.131 2.03 0.949 0.023 1.14 1.08 1.2 0.269 15900000 1 0 1.31 0.502 10.4 -0.199 2650 1 0 0.82 0.188 11.6 0.461 1080 1 0 1.59 0.728 1.63 PRS_PLINK_0.000199526231496888 TRUE 427.42 Cardiac arrest Both 3 9 8 circulatory system red 9, 3 3, 2 2, 1 2, 0 2, 0 0.0675 1.62 0.967 0.015 1.07 0.0362 36 0.00887 7020000 1 0 1.01 0.442 2.08 -0.00654 1870 1 0 0.993 0.607 2.37 -0.208 2930 1 0 0.812 0.262 0.908 PRS_PLINK_0.000199526231496888 TRUE 427.5 Arrhythmia (cardiac) NOS Both 62 215 8 circulatory system red 215, 62 53, 11 54, 15 53, 15 54, 21 0.313 0.16 0.0501 1.301 1.37 1.01 1.88 0.793 0.505 0.116 0.935 2.21 0.854 6.12 0.441 0.481 0.36 0.444 1.55 0.623 4.05 1 0.484 0.0386 1.413 2.72 1.1 7.34 PRS_PLINK_0.000199526231496888 FALSE 427.6 Premature beats Both 28 100 8 circulatory system red 100, 28 25, 5 25, 5 25, 8 25, 10 0.16 0.234 0.493 0.307 1.17 0.752 1.86 0.36 0.709 0.612 0.214 1.43 0.366 5.95 0.55 0.677 0.416 0.381 1.73 0.496 6.68 0.498 0.73 0.496 0.305 1.65 0.418 7.07 PRS_PLINK_0.000199526231496888 TRUE 427.61 Supraventricular premature beats Both 6 26 8 circulatory system red 26, 6 7, 1 6, 3 6, 0 7, 2 0.0386 0.49 0.937 0.028 1.04 0.394 2.54 0.849 1.41 0.547 0.262 2.34 0.275 37.4 -0.896 1.64 0.584 0.233 0.408 0.00683 14.9 0.417 1.51 0.783 0.106 1.52 0.0687 62.2 PRS_PLINK_0.000199526231496888 TRUE 427.7 Tachycardia NOS Both 78 215 8 circulatory system red 215, 78 53, 18 54, 25 53, 17 54, 18 -0.0865 0.141 0.538 0.269 0.917 0.698 1.21 0.415 0.388 0.285 0.546 1.52 0.724 3.22 0.0601 0.405 0.882 0.055 1.06 0.488 2.33 0.115 0.404 0.776 0.11 1.12 0.517 2.45 PRS_PLINK_0.000199526231496888 FALSE 427.8 Sinoatrial node dysfunction (Bradycardia) Both 10 25 8 circulatory system red 25, 10 7, 0 6, 2 6, 3 6, 5 0.45 0.425 0.29 0.538 1.57 0.745 4 2.33 3.13 0.457 0.34 10.3 0.094 12.6 0.747 2.01 0.71 0.149 2.11 0.0709 77400 3.17 2.12 0.136 0.867 23.7 1.1 10900 PRS_PLINK_0.000199526231496888 TRUE 427.9 Palpitations Both 92 213 8 circulatory system red 213, 92 53, 17 53, 25 53, 25 53, 25 0.122 0.141 0.387 0.412 1.13 0.861 1.49 0.574 0.398 0.149 0.827 1.78 0.831 3.88 0.336 0.391 0.39 0.409 1.4 0.662 3.01 0.666 0.416 0.109 0.961 1.95 0.885 4.42 PRS_PLINK_0.000199526231496888 FALSE 428 Congestive heart failure; nonhypertensive Both 21 124 8 circulatory system red 124, 21 31, 6 31, 5 31, 3 31, 7 0.205 0.254 0.42 0.377 1.23 0.749 2.04 -0.0364 0.663 0.956 0.019 0.964 0.259 3.6 -0.424 0.771 0.583 0.235 0.655 0.113 3.08 0.197 0.679 0.772 0.112 1.22 0.323 4.67 PRS_PLINK_0.000199526231496888 TRUE 428.1 Congestive heart failure (CHF) NOS Both 20 114 8 circulatory system red 114, 20 29, 5 28, 5 28, 3 29, 7 0.33 0.271 0.223 0.652 1.39 0.824 2.4 0.314 0.715 0.661 0.18 1.37 0.342 5.93 -0.124 0.818 0.88 0.056 0.884 0.143 4.86 0.606 0.749 0.418 0.378 1.83 0.438 8.88 PRS_PLINK_0.000199526231496888 TRUE 428.2 Heart failure NOS Both 11 105 8 circulatory system red 105, 11 27, 3 26, 4 26, 1 26, 3 0.0819 0.344 0.812 0.09 1.09 0.529 2.27 0.0636 0.839 0.94 0.027 1.07 0.162 6.32 -0.449 1.1 0.683 0.166 0.638 0.00638 7.63 0.199 0.884 0.822 0.085 1.22 0.186 7.62 PRS_PLINK_0.000199526231496888 TRUE 428.3 Heart failure with reduced EF [Systolic or combined heart failure] Both 7 68 8 circulatory system red 68, 7 17, 1 17, 4 17, 1 17, 1 0.0524 0.458 0.909 0.042 1.05 0.402 3.06 4.04 1.98 0.0415 1.382 57 1.77 513000 0.175 1.22 0.886 0.052 1.19 0.0374 78.7 0.861 1.51 0.568 0.246 2.37 0.056 45900 PRS_PLINK_0.000199526231496888 TRUE 428.4 Heart failure with preserved EF [Diastolic heart failure] Both 8 59 8 circulatory system red 59, 8 15, 3 15, 2 14, 1 15, 2 -0.225 0.562 0.689 0.162 0.799 0.169 2.57 -0.222 0.96 0.817 0.088 0.801 0.125 5.56 -0.945 1.27 0.458 0.339 0.389 0.00445 4.22 -0.628 1.33 0.636 0.197 0.533 0.442 18.5 PRS_PLINK_0.000199526231496888 TRUE 429 Ill-defined descriptions and complications of heart disease Both 159 288 8 circulatory system red 288, 159 71, 40 72, 35 72, 33 72, 51 0.0941 0.108 0.383 0.417 1.1 0.892 1.36 -0.0288 0.301 0.924 0.034 0.972 0.543 1.73 -0.268 0.31 0.388 0.412 0.765 0.42 1.38 0.341 0.294 0.247 0.607 1.41 0.801 2.49 PRS_PLINK_0.000199526231496888 FALSE 429.1 Heart transplant/surgery Both 14 54 8 circulatory system red 54, 14 14, 3 13, 2 13, 6 14, 3 0.197 0.329 0.549 0.26 1.22 0.655 2.39 1.01 1.32 0.446 0.35 2.74 0.233 62.2 -0.961 1.23 0.436 0.361 0.382 0.0164 4.55 0.076 1.15 0.947 0.023 1.08 0.0949 11.6 PRS_PLINK_0.000199526231496888 TRUE 429.2 Abnormal function study of cardiovascular system Both 60 247 8 circulatory system red 247, 60 61, 19 62, 10 61, 14 62, 17 0.17 0.159 0.285 0.545 1.19 0.871 1.62 -0.479 0.455 0.292 0.534 0.62 0.247 1.48 -0.255 0.427 0.55 0.259 0.775 0.336 1.76 0.191 0.446 0.669 0.175 1.21 0.512 2.92 PRS_PLINK_0.000199526231496888 FALSE 429.3 Symptoms involving cardiovascular system Both 136 288 8 circulatory system red 288, 136 71, 33 72, 31 72, 30 72, 42 0.0671 0.113 0.552 0.258 1.07 0.86 1.33 -0.00673 0.315 0.983 0.007 0.993 0.541 1.82 -0.157 0.32 0.623 0.205 0.854 0.459 1.58 0.341 0.308 0.269 0.571 1.41 0.78 2.56 PRS_PLINK_0.000199526231496888 FALSE 429.9 Cardiac complications, not elsewhere classified Both 2 25 8 circulatory system red 25, 2 7, 1 6, 1 6, 0 6, 0 -0.417 0.704 0.553 0.257 0.659 0.00468 3.05 -0.0192 1.85 0.992 0.004 0.981 0.0349 1090 -0.334 1.86 0.858 0.067 0.716 0.0113 18 -0.778 1.85 0.675 0.171 0.459 0.00702 126 PRS_PLINK_0.000199526231496888 TRUE 430 Intracranial hemorrhage Both 6 52 8 circulatory system red 52, 6 13, 0 13, 1 13, 3 13, 2 0.486 0.481 0.312 0.505 1.63 0.652 4.86 1.12 1.46 0.441 0.355 3.08 0.0584 660 0.269 1.3 0.836 0.078 1.31 0.0485 150 1.54 1.43 0.283 0.549 4.65 0.374 92300 PRS_PLINK_0.000199526231496888 TRUE 430.1 Subarachnoid hemorrhage Both 1 16 8 circulatory system red 16, 1 4, 0 4, 1 4, 0 4, 0 0.258 0.705 0.714 0.146 1.29 0.329 12.1 3.81 164 0.981 0.008 45.1 5.31e-08 2.37e+14 PRS_PLINK_0.000199526231496888 TRUE 430.2 Intracerebral hemorrhage Both 3 29 8 circulatory system red 29, 3 8, 0 7, 1 7, 1 7, 1 0.00921 0.641 0.989 0.005 1.01 0.212 3.84 0.415 1.73 0.81 0.091 1.51 0.00891 414 0.271 1.44 0.85 0.07 1.31 0.0272 26.7 0.606 1.64 0.711 0.148 1.83 0.0232 560 PRS_PLINK_0.000199526231496888 TRUE 430.3 Subdural hemorrhage Both 3 18 8 circulatory system red 18, 3 5, 0 4, 1 4, 2 5, 0 -0.141 0.749 0.851 0.07 0.868 0.184 3.36 -0.512 39.1 0.99 0.005 0.599 2.99e-07 1240000 0.159 3.31 0.962 0.017 1.17 0.00516 2310 PRS_PLINK_0.000199526231496888 TRUE 433 Cerebrovascular disease Both 31 232 8 circulatory system red 232, 31 58, 5 58, 6 58, 9 58, 11 0.342 0.201 0.0887 1.052 1.41 0.954 2.11 0.323 0.604 0.593 0.227 1.38 0.399 5.09 0.597 0.559 0.285 0.544 1.82 0.607 5.93 0.8 0.554 0.149 0.827 2.22 0.777 7.14 PRS_PLINK_0.000199526231496888 TRUE 433.1 Occlusion and stenosis of precerebral arteries Both 9 83 8 circulatory system red 83, 9 21, 2 21, 2 20, 1 21, 4 0.296 0.359 0.41 0.387 1.34 0.653 2.92 -0.096 0.984 0.922 0.035 0.908 0.109 8.59 -0.743 1.17 0.525 0.28 0.476 0.0168 5.25 0.494 0.936 0.597 0.224 1.64 0.261 12.8 PRS_PLINK_0.000199526231496888 TRUE 433.11 Occlusion of cerebral arteries, with cerebral infarction Both 1 12 8 circulatory system red 12, 1 3, 1 3, 0 3, 0 3, 0 -1.27 1.32 0.336 0.474 0.28 0.0105 1.7 -0.658 387 0.999 0.001 0.518 0.0914 0.469 -0.0757 67.2 0.999 0 0.927 0.604 0.469 0.242 1200 1 0 1.27 0.46 4.49 PRS_PLINK_0.000199526231496888 TRUE 433.12 Cerebral atherosclerosis Both 1 1 8 circulatory system red 1, 1 -0.00534 41.1 1 0 0.995 0.924 1.16 PRS_PLINK_0.000199526231496888 TRUE 433.2 Occlusion of cerebral arteries Both 13 139 8 circulatory system red 139, 13 35, 2 35, 5 34, 3 35, 3 0.263 0.285 0.355 0.449 1.3 0.742 2.35 1.2 0.902 0.182 0.739 3.33 0.585 29 1.02 1.01 0.309 0.511 2.78 0.346 32.5 0.615 0.886 0.487 0.312 1.85 0.275 15.6 PRS_PLINK_0.000199526231496888 TRUE 433.21 Cerebral artery occlusion, with cerebral infarction Both 12 132 8 circulatory system red 132, 12 33, 1 33, 6 33, 2 33, 3 0.367 0.322 0.255 0.594 1.44 0.762 2.9 1.94 1.02 0.0586 1.232 6.94 1.07 104 0.559 1.03 0.586 0.232 1.75 0.166 25.6 1.51 1.14 0.185 0.734 4.54 0.426 1100 PRS_PLINK_0.000199526231496888 TRUE 433.3 Cerebral ischemia Both 18 134 8 circulatory system red 134, 18 34, 2 33, 3 33, 6 34, 7 0.499 0.261 0.0559 1.253 1.65 1 2.84 0.553 0.842 0.511 0.291 1.74 0.304 12.6 0.836 0.735 0.256 0.592 2.31 0.548 13 1.37 0.832 0.0997 1.002 3.94 0.836 30.9 PRS_PLINK_0.000199526231496888 TRUE 433.31 Transient cerebral ischemia Both 13 127 8 circulatory system red 127, 13 32, 2 32, 2 31, 5 32, 4 0.382 0.308 0.215 0.668 1.47 0.799 2.85 0.139 0.915 0.88 0.056 1.15 0.15 8.64 0.617 0.741 0.405 0.393 1.85 0.424 10.2 0.536 0.936 0.567 0.247 1.71 0.252 17.6 PRS_PLINK_0.000199526231496888 TRUE 433.5 Cerebral aneurysm Both 3 30 8 circulatory system red 30, 3 8, 0 7, 0 7, 2 8, 1 0.488 0.663 0.461 0.336 1.63 0.479 13.5 1.05 1.49 0.48 0.319 2.87 0.222 12300 0.902 1.56 0.563 0.249 2.47 0.112 133 PRS_PLINK_0.000199526231496888 TRUE 433.6 Acute, but ill-defined cerebrovascular disease Both 4 27 8 circulatory system red 27, 4 7, 1 7, 1 6, 1 7, 1 -0.456 0.542 0.4 0.398 0.634 0.0281 1.8 0.142 1.29 0.913 0.04 1.15 0.151 25.4 0.101 1.27 0.937 0.028 1.11 0.136 9.62 0.229 1.38 0.868 0.062 1.26 0.126 37.3 PRS_PLINK_0.000199526231496888 TRUE 433.8 Late effects of cerebrovascular disease Both 5 46 8 circulatory system red 46, 5 12, 1 11, 2 11, 0 12, 2 -0.155 0.521 0.767 0.115 0.857 0.259 3.71 0.777 1.28 0.545 0.264 2.17 0.192 1940 -0.546 1.44 0.706 0.151 0.58 2.4e-05 212 0.867 1.29 0.503 0.298 2.38 0.175 85.3 PRS_PLINK_0.000199526231496888 TRUE 440 Atherosclerosis Both 22 103 8 circulatory system red 103, 22 26, 8 26, 5 25, 3 26, 6 -0.0375 0.219 0.864 0.063 0.963 0.624 1.48 -0.196 0.65 0.763 0.117 0.822 0.23 2.89 -0.81 0.744 0.276 0.559 0.445 0.0931 1.76 -0.231 0.651 0.722 0.141 0.793 0.216 2.73 PRS_PLINK_0.000199526231496888 TRUE 440.1 Atherosclerosis of renal artery Both 4 14 8 circulatory system red 14, 4 4, 2 3, 0 3, 2 4, 0 -0.301 0.624 0.63 0.201 0.74 0.216 2.53 4.44 399 0.991 0.004 84.5 8.01e-07 33100000 0.298 2.4 0.901 0.045 1.35 0.0389 55.4 4.16 22.3 0.852 0.07 63.9 9.77e-09 2.45e+11 PRS_PLINK_0.000199526231496888 TRUE 440.2 Atherosclerosis of the extremities Both 15 74 8 circulatory system red 74, 15 19, 5 18, 3 18, 4 19, 3 0.00935 0.249 0.97 0.013 1.01 0.622 1.65 -0.0158 0.91 0.986 0.006 0.984 0.151 6.88 -0.667 0.846 0.431 0.366 0.513 0.0793 2.43 -0.517 0.831 0.534 0.273 0.596 0.106 2.74 PRS_PLINK_0.000199526231496888 TRUE 440.21 Atherosclerosis of native arteries of the extremities with ulceration or gangrene Both 1 11 8 circulatory system red 11, 1 3, 0 3, 0 2, 0 3, 1 0.208 1.37 0.879 0.056 1.23 0.0345 21.8 2.48 2760 0.999 0 12 1.42e-08 1.5e+07 PRS_PLINK_0.000199526231496888 TRUE 440.22 Atherosclerosis of native arteries of the extremities with intermittent claudication Both 10 47 8 circulatory system red 47, 10 12, 4 12, 1 11, 3 12, 2 0.0134 0.295 0.964 0.016 1.01 0.571 1.77 -0.284 1.2 0.813 0.09 0.753 0.0459 10.9 -0.475 1.04 0.649 0.188 0.622 0.0451 4.03 -0.158 0.972 0.871 0.06 0.854 0.133 5.06 PRS_PLINK_0.000199526231496888 TRUE 440.9 Atherosclerosis of aorta Both 3 25 8 circulatory system red 25, 3 7, 0 6, 2 6, 0 6, 1 0.0844 0.655 0.898 0.047 1.09 0.262 5.68 2.72 2.72 0.317 0.499 15.1 0.278 138000 0.272 2.45 0.912 0.04 1.31 0.0369 26400 PRS_PLINK_0.000199526231496888 TRUE 441 Vascular insufficiency of intestine Both 6 30 8 circulatory system red 30, 6 8, 1 7, 1 7, 1 8, 3 0.52 0.591 0.379 0.421 1.68 0.517 7 -0.279 1.59 0.861 0.065 0.757 0.00689 16.9 -0.297 1.35 0.826 0.083 0.743 0.0742 7.05 0.658 1.26 0.602 0.22 1.93 0.224 35.7 PRS_PLINK_0.000199526231496888 TRUE 441.1 Acute vascular insufficiency of intestine Both 3 14 8 circulatory system red 14, 3 4, 0 3, 0 3, 1 4, 2 1.31 1.35 0.331 0.481 3.72 0.355 4720 -0.843 4.1 0.837 0.077 0.431 0.000352 298 1.43 2.68 0.593 0.227 4.18 0.0677 137 PRS_PLINK_0.000199526231496888 TRUE 441.2 Chronic vascular insufficiency of intestine Both 3 9 8 circulatory system red 9, 3 3, 1 2, 0 2, 1 2, 1 0.492 1.59 0.758 0.12 1.64 0.0652 1340 0.304 1520 1 0 1.36 0.625 3.09 0.152 62.2 0.998 0.001 1.16 2.62 2.52 1.25 730 0.999 0.001 3.49 0.0516 56.9 PRS_PLINK_0.000199526231496888 TRUE 442 Other aneurysm Both 25 105 8 circulatory system red 105, 25 27, 3 26, 8 26, 7 26, 7 0.262 0.247 0.287 0.542 1.3 0.811 2.15 1.1 0.768 0.151 0.821 3.01 0.729 16.5 0.994 0.728 0.172 0.764 2.7 0.704 12.8 0.798 0.77 0.3 0.523 2.22 0.519 11.3 PRS_PLINK_0.000199526231496888 TRUE 442.1 Aortic aneurysm Both 15 64 8 circulatory system red 64, 15 16, 2 16, 4 16, 5 16, 4 0.349 0.317 0.272 0.566 1.42 0.786 2.71 2.39 1.45 0.0995 1.002 10.9 1.02 1020 1.32 1.12 0.236 0.626 3.74 0.557 78.6 0.805 0.986 0.415 0.382 2.24 0.355 16.9 PRS_PLINK_0.000199526231496888 TRUE 442.11 Abdominal aortic aneurysm Both 7 31 8 circulatory system red 31, 7 8, 0 8, 1 7, 3 8, 3 0.649 0.473 0.17 0.769 1.91 0.85 7.47 1.24 1.65 0.451 0.345 3.45 0.211 139 1.57 1.47 0.287 0.542 4.8 0.479 17700 0.396 1.58 0.802 0.096 1.49 0.0397 1120000 PRS_PLINK_0.000199526231496888 TRUE 442.2 Aneurysm of iliac artery Both 1 5 8 circulatory system red 5, 1 2, 0 1, 0 1, 0 1, 1 -0.0984 2210 1 0 0.906 0.388 1.38 -0.067 2040 1 0 0.935 0.428 1.35 PRS_PLINK_0.000199526231496888 TRUE 442.3 Aneurysm of artery of lower extremity Both 1 8 8 circulatory system red 8, 1 2, 0 2, 0 2, 0 2, 1 -0.784 5.57 0.888 0.052 0.457 0.376 2410 -0.013 3800 1 0 0.987 0.315 7.32 PRS_PLINK_0.000199526231496888 TRUE 442.4 Arterial dissection Both 4 12 8 circulatory system red 12, 4 3, 1 3, 1 3, 0 3, 2 -0.568 0.686 0.407 0.39 0.566 0.0239 1.76 1.34 445 0.998 0.001 3.8 1.71 2.39 -0.339 357000 1 0 0.713 0.456 0.94 -1.86 3.64 0.609 0.215 0.156 0.139 16.3 PRS_PLINK_0.000199526231496888 TRUE 442.8 Aneurysm of other specified artery Both 8 23 8 circulatory system red 23, 8 6, 2 6, 2 5, 3 6, 1 -0.0577 0.477 0.904 0.044 0.944 0.365 2.25 -0.393 1.46 0.788 0.103 0.675 0.0914 7.66 0.776 1.84 0.673 0.172 2.17 0.00839 292 -0.173 1.4 0.902 0.045 0.841 0.053 13.3 PRS_PLINK_0.000199526231496888 TRUE 443 Peripheral vascular disease Both 30 155 8 circulatory system red 155, 30 39, 8 39, 9 38, 4 39, 9 0.0749 0.202 0.71 0.149 1.08 0.725 1.61 0.0927 0.589 0.875 0.058 1.1 0.347 3.51 -0.874 0.734 0.234 0.631 0.417 0.0766 1.71 -0.0272 0.596 0.964 0.016 0.973 0.3 3.12 PRS_PLINK_0.000199526231496888 TRUE 443.1 Raynaud's syndrome Both 13 80 8 circulatory system red 80, 13 20, 4 20, 4 20, 3 20, 2 -0.153 0.309 0.621 0.207 0.858 0.443 1.54 0.415 0.95 0.662 0.179 1.51 0.25 14.2 0.239 0.997 0.81 0.091 1.27 0.177 9.78 -0.834 1.01 0.407 0.39 0.434 0.0269 2.94 PRS_PLINK_0.000199526231496888 TRUE 443.7 Peripheral angiopathy in diseases classified elsewhere Both 1 10 8 circulatory system red 10, 1 3, 0 2, 0 2, 0 3, 1 0.37 2.45 0.88 0.056 1.45 0.0397 178 -0.0719 1480 1 0 0.931 0.296 2.53 PRS_PLINK_0.000199526231496888 TRUE 443.8 Other specified peripheral vascular diseases Both 29 136 8 circulatory system red 136, 29 34, 6 34, 10 34, 6 34, 7 0.118 0.206 0.566 0.247 1.13 0.753 1.7 0.441 0.64 0.491 0.309 1.55 0.453 5.63 -0.364 0.742 0.624 0.205 0.695 0.135 3.04 0.131 0.656 0.841 0.075 1.14 0.31 4.32 PRS_PLINK_0.000199526231496888 TRUE 443.9 Peripheral vascular disease, unspecified Both 17 92 8 circulatory system red 92, 17 23, 3 23, 6 23, 2 23, 6 0.479 0.31 0.123 0.912 1.61 0.895 3.15 0.272 0.967 0.779 0.109 1.31 0.175 11 -0.124 1.01 0.903 0.044 0.884 0.0708 8.12 0.947 0.915 0.301 0.522 2.58 0.439 22.5 PRS_PLINK_0.000199526231496888 TRUE 444 Arterial embolism and thrombosis Both 8 66 8 circulatory system red 66, 8 17, 1 16, 0 16, 4 17, 3 0.598 0.43 0.165 0.783 1.82 0.803 4.56 -0.52 1.29 0.686 0.164 0.594 0.00674 20.6 2.44 1.45 0.0916 1.038 11.5 0.895 1150 0.771 1.24 0.535 0.271 2.16 0.16 26.1 PRS_PLINK_0.000199526231496888 TRUE 444.1 Arterial embolism and thrombosis of lower extremity artery Both 2 22 8 circulatory system red 22, 2 6, 0 5, 0 5, 1 6, 1 0.0178 0.811 0.982 0.008 1.02 0.0527 159 1.53 3.19 0.632 0.199 4.6 0.00422 2950 -0.27 2.16 0.901 0.045 0.763 0.00068 1500 PRS_PLINK_0.000199526231496888 TRUE 444.2 Embolism and thrombosis of abdominal aorta Both 1 3 8 circulatory system red 3, 1 1, 0 1, 0 0, 1 1, 0 0.036 4990 1 0 1.04 0.275 4.25 -0.0219 32.7 0.999 0 0.978 0.701 4.32 PRS_PLINK_0.000199526231496888 TRUE 446 Polyarteritis nodosa and allied conditions Both 10 39 8 circulatory system red 39, 10 10, 4 10, 4 9, 1 10, 1 -0.458 0.429 0.286 0.544 0.632 0.257 1.37 0.266 1.31 0.839 0.076 1.3 0.118 31.8 -2.36 2.04 0.248 0.606 0.0944 5.39e-05 2.71 -2.4 1.73 0.165 0.782 0.0911 1e-04 1.53 PRS_PLINK_0.000199526231496888 TRUE 446.4 Wegener's granulomatosis Both 2 9 8 circulatory system red 9, 2 3, 2 2, 0 2, 0 2, 0 -0.571 1.35 0.673 0.172 0.565 0.0632 4.51 0.131 2330 1 0 1.14 0.586 4.78 -0.0996 1660 1 0 0.905 0.477 1.22 -0.032 149 1 0 0.969 0.418 2.68 PRS_PLINK_0.000199526231496888 TRUE 446.5 Giant cell arteritis Both 1 2 8 circulatory system red 2, 1 1, 0 1, 1 1, 0 1, 1 -0.0061 159 1 0 0.994 0.911 1.1 0.00197 49.8 1 0 1 0.96 1.04 PRS_PLINK_0.000199526231496888 TRUE 446.9 Arteritis NOS Both 9 20 8 circulatory system red 20, 9 5, 1 5, 4 5, 2 5, 2 0.0436 0.706 0.951 0.022 1.04 0.246 6.8 -1.15 2.93 0.696 0.157 0.318 0.000145 42 0.534 4.27 0.901 0.045 1.7 1.14e-06 2400 -0.088 2.21 0.968 0.014 0.916 0.00629 245 PRS_PLINK_0.000199526231496888 TRUE 447 Other disorders of arteries and arterioles Both 29 132 8 circulatory system red 132, 29 32, 12 33, 7 33, 6 33, 4 -0.261 0.211 0.217 0.663 0.771 0.506 1.16 -0.429 0.568 0.45 0.347 0.651 0.215 1.9 -0.216 0.644 0.737 0.132 0.806 0.226 2.85 -0.952 0.652 0.144 0.84 0.386 0.0997 1.29 PRS_PLINK_0.000199526231496888 TRUE 447.1 Stricture of artery Both 3 26 8 circulatory system red 26, 3 7, 0 6, 1 6, 0 7, 2 -0.0313 0.626 0.96 0.018 0.969 0.023 7.32 -2.04 3.18 0.52 0.284 0.129 3.57e-05 122 1.24 1.6 0.438 0.359 3.46 0.156 66.3 PRS_PLINK_0.000199526231496888 TRUE 447.7 Aortic ectasia Both 6 32 8 circulatory system red 32, 6 8, 2 8, 1 8, 2 8, 1 -0.142 0.468 0.761 0.119 0.867 0.348 2.16 -0.339 1.43 0.812 0.09 0.712 0.0116 30.3 1.98 1.77 0.262 0.582 7.27 0.469 30800 -0.287 1.38 0.835 0.078 0.751 2.74e-05 10.8 PRS_PLINK_0.000199526231496888 TRUE 448 Disease of capillaries Both 23 76 8 circulatory system red 76, 23 19, 6 19, 5 19, 7 19, 5 0.0622 0.262 0.813 0.09 1.06 0.649 1.78 -0.339 0.747 0.65 0.187 0.712 0.162 2.84 0.362 0.827 0.662 0.179 1.44 0.298 8.15 0.173 0.81 0.83 0.081 1.19 0.263 5.74 PRS_PLINK_0.000199526231496888 TRUE 450 Noninfectious disorders of lymphatic channels Both 27 190 8 circulatory system red 190, 27 48, 4 47, 10 47, 8 48, 5 0.0512 0.212 0.809 0.092 1.05 0.691 1.61 1.08 0.622 0.082 1.086 2.95 0.909 12 0.617 0.653 0.345 0.463 1.85 0.521 7.73 0.418 0.636 0.511 0.291 1.52 0.42 5.77 PRS_PLINK_0.000199526231496888 TRUE 451 Phlebitis and thrombophlebitis Both 14 54 8 circulatory system red 54, 14 13, 5 13, 5 13, 1 14, 3 -0.215 0.299 0.472 0.326 0.806 0.451 1.43 0.941 1.06 0.375 0.426 2.56 0.372 28.1 -0.918 1.19 0.441 0.356 0.399 0.0154 3.46 -0.29 0.964 0.763 0.117 0.748 0.111 5.39 PRS_PLINK_0.000199526231496888 TRUE 451.2 Phlebitis and thrombophlebitis of lower extremities Both 5 27 8 circulatory system red 27, 5 7, 2 7, 2 6, 0 7, 1 -0.321 0.483 0.506 0.296 0.725 0.271 1.8 -0.14 1.3 0.914 0.039 0.869 0.0381 13.3 -0.411 1.55 0.791 0.102 0.663 0.027 11.3 -0.128 1.46 0.93 0.031 0.88 0.0608 14.4 PRS_PLINK_0.000199526231496888 TRUE 452 Other venous embolism and thrombosis Both 49 239 8 circulatory system red 239, 49 59, 16 60, 13 59, 9 60, 11 -0.285 0.183 0.119 0.925 0.752 0.524 1.07 -0.347 0.445 0.435 0.361 0.706 0.294 1.66 -0.64 0.52 0.218 0.662 0.527 0.184 1.41 -0.747 0.488 0.126 0.901 0.474 0.177 1.18 PRS_PLINK_0.000199526231496888 TRUE 452.1 Iatrogenic pulmonary embolism and infarction Both 8 19 8 circulatory system red 19, 8 5, 2 5, 5 4, 1 5, 0 -0.275 0.473 0.561 0.251 0.76 0.304 1.72 1.4 1.35 0.302 0.519 4.04 0.498 190 -1.17 1.93 0.545 0.264 0.312 0.00554 9.02 1.18 3.19 0.711 0.148 3.26 2.81 3.68 PRS_PLINK_0.000199526231496888 TRUE 452.2 Deep vein thrombosis [DVT] Both 34 186 8 circulatory system red 186, 34 46, 8 46, 11 46, 6 47, 9 -0.138 0.212 0.515 0.288 0.871 0.572 1.32 0.258 0.525 0.623 0.206 1.29 0.469 3.66 -0.516 0.618 0.404 0.394 0.597 0.164 1.96 -0.211 0.548 0.701 0.154 0.81 0.271 2.35 PRS_PLINK_0.000199526231496888 TRUE 452.8 Postphlebitic syndrome Both 2 10 8 circulatory system red 10, 2 3, 0 2, 0 2, 1 3, 1 -0.335 1.76 0.849 0.071 0.715 0.0211 25.2 -0.71 1070 0.999 0 0.491 6.17e-05 80.1 -0.228 5200 1 0 0.796 0.703 1.61 PRS_PLINK_0.000199526231496888 TRUE 453 Chronic venous hypertension Both 5 16 8 circulatory system red 16, 5 3, 2 4, 0 4, 1 4, 2 -0.577 0.563 0.305 0.516 0.561 0.52 1.4 -0.825 4.38 0.851 0.07 0.438 0.011 21.2 -1.4 2.62 0.593 0.227 0.246 0.000359 111 -0.705 4.44 0.874 0.059 0.494 4.34e-05 1810 PRS_PLINK_0.000199526231496888 TRUE 454 Varicose veins Both 47 170 8 circulatory system red 170, 47 42, 13 42, 15 42, 7 43, 12 -0.288 0.185 0.119 0.926 0.749 0.52 1.07 0.154 0.473 0.745 0.128 1.17 0.474 2.91 -0.861 0.573 0.133 0.875 0.423 0.126 1.24 -0.584 0.543 0.282 0.55 0.558 0.189 1.55 PRS_PLINK_0.000199526231496888 TRUE 454.1 Varicose veins of lower extremity Both 45 157 8 circulatory system red 157, 45 39, 13 39, 15 39, 5 39, 12 -0.287 0.189 0.129 0.89 0.751 0.517 1.08 0.198 0.473 0.675 0.171 1.22 0.497 3.04 -1.31 0.662 0.0471 1.327 0.269 0.0605 0.918 -0.431 0.555 0.437 0.359 0.65 0.215 1.86 PRS_PLINK_0.000199526231496888 TRUE 454.11 Varicose veins of lower extremity, symptomtic Both 29 99 8 circulatory system red 99, 29 24, 8 25, 8 24, 5 25, 8 -0.296 0.242 0.222 0.653 0.744 0.459 1.19 -0.299 0.663 0.652 0.185 0.742 0.197 2.63 -0.705 0.733 0.336 0.473 0.494 0.11 1.91 -0.969 0.809 0.231 0.637 0.379 0.0678 1.74 PRS_PLINK_0.000199526231496888 TRUE 455 Hemorrhoids Both 90 255 8 circulatory system red 255, 90 63, 24 64, 21 63, 22 64, 23 0.0111 0.143 0.938 0.028 1.01 0.766 1.34 -0.0558 0.39 0.886 0.053 0.946 0.444 2.01 -0.0626 0.399 0.875 0.058 0.939 0.432 2.03 -0.135 0.394 0.732 0.136 0.874 0.405 1.86 PRS_PLINK_0.000199526231496888 FALSE 456 Chronic venous insufficiency [CVI] Both 74 191 8 circulatory system red 191, 74 47, 28 48, 16 47, 12 48, 18 -0.369 0.157 0.019 1.721 0.691 0.507 0.934 -0.835 0.427 0.0506 1.295 0.434 0.186 0.962 -1.06 0.447 0.0181 1.742 0.348 0.142 0.797 -0.974 0.43 0.0234 1.63 0.378 0.161 0.84 PRS_PLINK_0.000199526231496888 FALSE 457 Encounter for long-term (current) use of anticoagulants, antithrombotics, aspirin Both 12 60 8 circulatory system red 60, 12 15, 7 15, 2 15, 1 15, 2 -0.4 0.358 0.265 0.577 0.671 0.315 1.42 -0.0595 1.12 0.958 0.019 0.942 0.0994 11.7 -2.13 1.29 0.0994 1.003 0.119 0.00442 1.1 -0.87 1.04 0.401 0.397 0.419 0.0307 2.85 PRS_PLINK_0.000199526231496888 TRUE 457.2 Encounter for long-term (current) use of antiplatelets/antithrombotics Both 2 7 8 circulatory system red 7, 2 2, 1 2, 0 1, 0 2, 1 2.09 210 0.992 0.003 8.08 0.25 2950 1.43 14400000 1 0 4.17 0.000588 42600 -0.199 6510 1 0 0.819 0.149 3.28 -0.159 2700 1 0 0.853 0.234 2.57 PRS_PLINK_0.000199526231496888 TRUE 457.3 Encounter for long-term (current) use of aspirin Both 12 59 8 circulatory system red 59, 12 15, 7 15, 2 14, 1 15, 2 -0.4 0.358 0.264 0.579 0.67 0.315 1.41 -0.122 1.14 0.915 0.039 0.886 0.0916 11.7 -2.13 1.31 0.103 0.987 0.119 0.00437 1.12 -0.87 1.04 0.401 0.397 0.419 0.0307 2.85 PRS_PLINK_0.000199526231496888 TRUE 458 Hypotension Both 51 270 8 circulatory system red 270, 51 67, 19 67, 11 67, 10 68, 11 -0.0383 0.164 0.815 0.089 0.962 0.697 1.33 -0.464 0.432 0.282 0.55 0.629 0.264 1.44 -0.59 0.456 0.195 0.71 0.554 0.221 1.32 -0.0669 0.445 0.881 0.055 0.935 0.39 2.22 PRS_PLINK_0.000199526231496888 FALSE 458.1 Orthostatic hypotension Both 20 90 8 circulatory system red 90, 20 22, 7 22, 4 22, 4 23, 5 -0.175 0.258 0.498 0.303 0.84 0.509 1.38 0.0324 0.739 0.965 0.015 1.03 0.248 4.28 -0.735 0.814 0.367 0.436 0.48 0.0811 2.21 0.22 0.742 0.767 0.115 1.25 0.286 5.53 PRS_PLINK_0.000199526231496888 TRUE 458.2 Iatrogenic hypotension Both 8 54 8 circulatory system red 54, 8 14, 2 13, 1 13, 4 14, 1 -0.138 0.415 0.74 0.13 0.871 0.376 2.01 -1.82 1.73 0.295 0.53 0.163 7.89e-05 3.93 0.458 1.09 0.675 0.171 1.58 0.2 13.7 0.0716 1.29 0.956 0.02 1.07 0.0742 14.4 PRS_PLINK_0.000199526231496888 TRUE 458.9 Hypotension NOS Both 43 253 8 circulatory system red 253, 43 63, 17 63, 7 63, 10 63, 9 -0.0235 0.179 0.895 0.048 0.977 0.687 1.39 -0.666 0.485 0.17 0.77 0.514 0.19 1.29 -0.462 0.468 0.324 0.49 0.63 0.246 1.54 -0.0603 0.484 0.901 0.045 0.941 0.363 2.41 PRS_PLINK_0.000199526231496888 TRUE 459 Other disorders of circulatory system Both 79 324 8 circulatory system red 324, 79 80, 22 81, 22 81, 13 81, 22 -0.00475 0.139 0.973 0.012 0.995 0.758 1.31 0.153 0.361 0.672 0.172 1.16 0.578 2.36 -0.463 0.423 0.274 0.562 0.63 0.27 1.42 0.164 0.376 0.664 0.178 1.18 0.568 2.45 PRS_PLINK_0.000199526231496888 FALSE 459.1 Hemorrhage NOS Both 16 50 8 circulatory system red 50, 16 13, 6 12, 3 12, 4 13, 3 0.0314 0.293 0.915 0.039 1.03 0.585 1.83 -0.481 0.922 0.602 0.221 0.618 0.0986 3.19 -0.219 0.88 0.803 0.095 0.803 0.149 4.05 0.177 1.04 0.866 0.063 1.19 0.144 10.5 PRS_PLINK_0.000199526231496888 TRUE 459.7 Blood vessel replaced Both 4 87 8 circulatory system red 87, 4 21, 0 22, 0 21, 2 22, 2 0.87 0.619 0.16 0.796 2.39 0.704 18.1 1.45 1.34 0.28 0.552 4.27 0.257 803 1.27 1.5 0.396 0.402 3.56 0.0878 28800 PRS_PLINK_0.000199526231496888 TRUE 459.9 Circulatory disease NEC Both 65 307 8 circulatory system red 307, 65 76, 17 77, 19 76, 10 77, 19 0.04 0.153 0.793 0.101 1.04 0.773 1.41 0.204 0.395 0.605 0.218 1.23 0.57 2.67 -0.412 0.469 0.38 0.42 0.662 0.257 1.64 0.214 0.414 0.605 0.218 1.24 0.556 2.79 PRS_PLINK_0.000199526231496888 FALSE 464 Acute sinusitis Both 136 199 9 respiratory coral4 199, 136 49, 34 50, 43 49, 30 50, 29 -0.0918 0.119 0.442 0.355 0.912 0.724 1.15 0.229 0.331 0.49 0.31 1.26 0.667 2.38 -0.404 0.361 0.263 0.58 0.667 0.329 1.33 -0.265 0.357 0.459 0.338 0.767 0.385 1.51 PRS_PLINK_0.000199526231496888 FALSE 465 Acute upper respiratory infections of multiple or unspecified sites Both 224 207 9 respiratory coral4 207, 224 51, 51 52, 69 51, 50 52, 54 -0.026 0.103 0.801 0.096 0.974 0.798 1.19 0.297 0.297 0.316 0.5 1.35 0.761 2.39 -0.27 0.304 0.374 0.427 0.764 0.423 1.37 -0.106 0.303 0.726 0.139 0.899 0.501 1.61 PRS_PLINK_0.000199526231496888 FALSE 465.2 Acute pharyngitis Both 161 194 9 respiratory coral4 194, 161 48, 36 48, 56 48, 35 49, 34 -0.0943 0.116 0.414 0.383 0.91 0.727 1.14 0.511 0.321 0.111 0.954 1.67 0.906 3.11 -0.219 0.331 0.508 0.294 0.803 0.424 1.51 -0.233 0.34 0.494 0.307 0.792 0.411 1.51 PRS_PLINK_0.000199526231496888 FALSE 465.4 Acute laryngitis and tracheitis Both 8 27 9 respiratory coral4 27, 8 6, 3 7, 2 6, 2 7, 1 -0.352 0.429 0.412 0.385 0.703 0.26 1.54 0.465 1.33 0.726 0.139 1.59 0.14 1.75 -0.366 1.13 0.747 0.127 0.693 0.0882 4.24 -0.0591 1.39 0.966 0.015 0.943 0.682 14.6 PRS_PLINK_0.000199526231496888 TRUE 470 Septal Deviations/Turbinate Hypertrophy Both 29 114 9 respiratory coral4 114, 29 29, 5 28, 7 28, 11 29, 6 0.184 0.25 0.461 0.336 1.2 0.739 1.97 0.566 0.702 0.421 0.376 1.76 0.462 7.51 0.828 0.636 0.193 0.715 2.29 0.699 8.38 0.095 0.723 0.895 0.048 1.1 0.273 4.7 PRS_PLINK_0.000199526231496888 TRUE 471 Nasal polyps Both 10 52 9 respiratory coral4 52, 10 13, 2 13, 0 13, 3 13, 5 0.402 0.411 0.328 0.484 1.49 0.687 3.57 -0.846 1.43 0.555 0.256 0.429 0.000781 11.6 0.516 1.2 0.668 0.175 1.67 0.174 29.4 0.251 1.28 0.845 0.073 1.29 0.0775 86.6 PRS_PLINK_0.000199526231496888 TRUE 472 Chronic pharyngitis and nasopharyngitis Both 37 117 9 respiratory coral4 117, 37 30, 9 29, 11 29, 7 29, 10 0.017 0.218 0.938 0.028 1.02 0.664 1.56 0.221 0.591 0.708 0.15 1.25 0.396 3.99 -0.148 0.616 0.811 0.091 0.863 0.26 2.78 0.114 0.619 0.854 0.069 1.12 0.337 3.75 PRS_PLINK_0.000199526231496888 TRUE 473 Diseases of the larynx and vocal cords Both 31 148 9 respiratory coral4 148, 31 37, 8 37, 3 37, 10 37, 10 0.138 0.211 0.512 0.291 1.15 0.762 1.74 -1.47 0.814 0.0716 1.145 0.231 0.0352 1.06 -0.288 0.645 0.655 0.184 0.749 0.205 2.62 0.164 0.573 0.775 0.111 1.18 0.387 3.58 PRS_PLINK_0.000199526231496888 TRUE 473.1 Chronic laryngitis Both 0 5 9 respiratory coral4 5, 0 2 1 1 1 PRS_PLINK_0.000199526231496888 TRUE 473.3 Paralysis/spasm of vocal cords or larynx Both 4 25 9 respiratory coral4 25, 4 7, 1 6, 0 6, 2 6, 1 -0.0787 0.763 0.918 0.037 0.924 0.122 4.34 -0.106 1.59 0.947 0.024 0.9 0.00209 17 1.21 1.93 0.53 0.276 3.37 0.154 792 0.919 2.4 0.702 0.154 2.51 0.00967 670 PRS_PLINK_0.000199526231496888 TRUE 473.4 Voice disturbance Both 26 113 9 respiratory coral4 113, 26 29, 6 28, 2 28, 8 28, 10 0.278 0.229 0.226 0.645 1.32 0.85 2.09 -1.14 0.897 0.203 0.693 0.319 0.0401 1.72 -0.106 0.767 0.89 0.051 0.9 0.185 4.09 0.41 0.643 0.524 0.281 1.51 0.449 5.32 PRS_PLINK_0.000199526231496888 TRUE 474 Acute and chronic tonsillitis Both 21 96 9 respiratory coral4 96, 21 24, 4 24, 9 24, 4 24, 4 -0.328 0.267 0.22 0.657 0.72 0.422 1.2 0.218 0.713 0.759 0.119 1.24 0.302 5.26 -0.31 0.767 0.686 0.164 0.733 0.154 3.26 -0.312 0.846 0.712 0.147 0.732 0.13 3.91 PRS_PLINK_0.000199526231496888 TRUE 474.1 Acute tonsillitis Both 9 41 9 respiratory coral4 41, 9 11, 1 10, 3 10, 3 10, 2 -0.0675 0.441 0.878 0.056 0.935 0.384 2.23 2.11 1.97 0.284 0.547 8.26 0.316 25000 1.16 1.53 0.448 0.349 3.19 0.143 463 -1.24 1.66 0.454 0.343 0.289 0.000693 6.13 PRS_PLINK_0.000199526231496888 TRUE 474.2 Chronic tonsillitis and adenoiditis Both 15 82 9 respiratory coral4 82, 15 21, 4 20, 6 20, 3 21, 2 -0.608 0.332 0.067 1.174 0.545 0.27 1.02 -0.138 0.761 0.856 0.067 0.871 0.189 3.88 -0.664 0.858 0.439 0.357 0.515 0.0748 2.64 -0.824 0.917 0.369 0.433 0.439 0.0518 2.59 PRS_PLINK_0.000199526231496888 TRUE 475 Chronic sinusitis Both 89 176 9 respiratory coral4 176, 89 44, 24 44, 11 44, 30 44, 24 -0.0523 0.145 0.718 0.144 0.949 0.718 1.25 -1.17 0.51 0.0219 1.659 0.311 0.108 0.806 -0.128 0.404 0.751 0.124 0.88 0.401 1.91 -0.305 0.422 0.47 0.328 0.737 0.326 1.64 PRS_PLINK_0.000199526231496888 FALSE 475.9 Postnasal drip Both 23 51 9 respiratory coral4 51, 23 13, 5 13, 10 12, 2 13, 6 -0.0269 0.303 0.929 0.032 0.973 0.55 1.73 0.448 0.977 0.646 0.19 1.57 0.253 12.1 -0.64 1.01 0.527 0.278 0.527 0.0677 3.38 1.04 1.08 0.336 0.474 2.82 0.423 36 PRS_PLINK_0.000199526231496888 TRUE 476 Allergic rhinitis Both 206 177 9 respiratory coral4 177, 206 45, 54 44, 34 44, 61 44, 56 0.00742 0.109 0.946 0.024 1.01 0.816 1.24 -0.602 0.338 0.0748 1.126 0.547 0.283 1.04 0.0503 0.301 0.868 0.062 1.05 0.588 1.88 -0.0886 0.314 0.778 0.109 0.915 0.499 1.67 PRS_PLINK_0.000199526231496888 FALSE 477 Epistaxis or throat hemorrhage Both 12 74 9 respiratory coral4 74, 12 19, 1 18, 0 18, 11 19, 0 0.195 0.38 0.607 0.217 1.22 0.58 2.65 -0.887 1.48 0.549 0.261 0.412 0.000772 55.9 2.6 1.17 0.026 1.584 13.5 1.78 249 -1.43 1.45 0.324 0.49 0.238 0.00195 4.7 PRS_PLINK_0.000199526231496888 TRUE 478 Throat pain Both 9 29 9 respiratory coral4 29, 9 8, 1 7, 2 7, 3 7, 3 0.861 0.606 0.155 0.809 2.37 0.861 9.56 -0.719 1.55 0.642 0.192 0.487 0.00173 7.25 1.04 1.42 0.467 0.331 2.82 0.27 9930 1.74 1.62 0.282 0.55 5.7 0.334 6440 PRS_PLINK_0.000199526231496888 TRUE 479 Other upper respiratory disease Both 83 177 9 respiratory coral4 177, 83 45, 27 44, 14 44, 24 44, 18 -0.177 0.147 0.229 0.641 0.838 0.629 1.11 -0.749 0.432 0.0828 1.082 0.473 0.2 1.06 -0.245 0.395 0.535 0.272 0.783 0.363 1.66 -0.59 0.416 0.156 0.807 0.554 0.248 1.21 PRS_PLINK_0.000199526231496888 FALSE 480 Pneumonia Both 74 305 9 respiratory coral4 305, 74 76, 24 76, 21 76, 16 76, 13 -0.0721 0.133 0.588 0.23 0.93 0.717 1.21 -0.0686 0.356 0.847 0.072 0.934 0.464 1.87 -0.33 0.379 0.384 0.415 0.719 0.34 1.49 -0.421 0.382 0.27 0.568 0.656 0.305 1.37 PRS_PLINK_0.000199526231496888 FALSE 480.1 Bacterial pneumonia Both 11 67 9 respiratory coral4 67, 11 17, 4 17, 1 16, 4 17, 2 -0.131 0.304 0.667 0.176 0.877 0.477 1.6 -4.83 2.39 0.0436 1.361 0.00796 4.78e-08 0.526 0.118 0.849 0.889 0.051 1.13 0.233 5.89 -1.23 1.07 0.252 0.598 0.294 0.031 2.01 PRS_PLINK_0.000199526231496888 TRUE 480.11 Pneumococcal pneumonia Both 4 31 9 respiratory coral4 31, 4 8, 0 8, 0 7, 2 8, 2 1.01 0.618 0.104 0.984 2.73 0.927 24.9 2.74 2.14 0.201 0.697 15.4 0.519 22200000 1.6 1.49 0.283 0.548 4.97 0.497 137 PRS_PLINK_0.000199526231496888 TRUE 480.12 Pseudomonal pneumonia Both 0 10 9 respiratory coral4 10, 0 3 2 2 3 PRS_PLINK_0.000199526231496888 TRUE 480.13 MRSA pneumonia Both 1 7 9 respiratory coral4 7, 1 2, 1 2, 0 1, 0 2, 0 1.35 5220000 1 0 3.85 0.0387 201 -0.376 3450 1 0 0.687 0.163 3.04 -0.149 12700 1 0 0.861 0.0503 11.2 -0.876 17900 1 0 0.416 4.31e-05 1330 PRS_PLINK_0.000199526231496888 TRUE 480.2 Viral pneumonia Both 1 6 9 respiratory coral4 6, 1 2, 0 1, 0 1, 0 2, 1 0.147 335 1 0 1.16 0.404 2.75 0.524 13300000 1 0 1.69 0.41 6.9 PRS_PLINK_0.000199526231496888 TRUE 480.3 Pneumonia due to fungus (mycoses) Both 1 16 9 respiratory coral4 16, 1 4, 0 4, 0 4, 0 4, 1 0.4 0.818 0.625 0.204 1.49 0.209 24.8 -0.156 6.18 0.98 0.009 0.856 0.54 0.769 PRS_PLINK_0.000199526231496888 TRUE 480.5 Bronchopneumonia and lung abscess Both 0 6 9 respiratory coral4 6, 0 2 1 1 2 PRS_PLINK_0.000199526231496888 TRUE 481 Influenza Both 31 129 9 respiratory coral4 129, 31 32, 8 32, 8 32, 5 32, 10 0.0599 0.214 0.78 0.108 1.06 0.7 1.63 -0.00814 0.554 0.988 0.005 0.992 0.341 2.91 -0.394 0.66 0.55 0.259 0.674 0.178 2.43 0.254 0.603 0.673 0.172 1.29 0.406 4.26 PRS_PLINK_0.000199526231496888 TRUE 483 Acute bronchitis and bronchiolitis Both 72 260 9 respiratory coral4 260, 72 64, 21 65, 18 65, 20 65, 13 -0.169 0.141 0.23 0.638 0.845 0.641 1.11 -0.218 0.398 0.583 0.234 0.804 0.364 1.75 -0.163 0.378 0.666 0.176 0.85 0.407 1.76 -0.684 0.428 0.11 0.958 0.505 0.214 1.14 PRS_PLINK_0.000199526231496888 FALSE 495 Asthma Both 127 293 9 respiratory coral4 293, 127 74, 30 73, 22 73, 38 73, 36 0.0214 0.111 0.847 0.072 1.02 0.824 1.27 -0.308 0.336 0.359 0.445 0.735 0.381 1.4 0.171 0.315 0.588 0.231 1.19 0.644 2.2 0.0138 0.318 0.965 0.015 1.01 0.549 1.87 PRS_PLINK_0.000199526231496888 FALSE 495.1 Chronic obstructive asthma Both 4 34 9 respiratory coral4 34, 4 9, 1 8, 1 8, 2 9, 0 -0.303 0.67 0.652 0.186 0.739 0.0219 3.11 -0.632 1.53 0.679 0.168 0.532 0.000121 12 -1.33 2.03 0.512 0.291 0.264 6.49e-08 9.15 -1.3 1.74 0.457 0.34 0.274 5.3e-06 5.6 PRS_PLINK_0.000199526231496888 TRUE 495.11 Chronic obstructive asthma with exacerbation Both 2 8 9 respiratory coral4 8, 2 2, 0 2, 2 2, 0 2, 0 -0.542 14.9 0.971 0.013 0.581 0.564 0.599 -0.151 670 1 0 0.86 0.0782 5.43 PRS_PLINK_0.000199526231496888 TRUE 495.2 Asthma with exacerbation Both 42 197 9 respiratory coral4 197, 42 50, 9 49, 7 49, 14 49, 12 -0.0282 0.173 0.87 0.06 0.972 0.692 1.37 -0.224 0.565 0.691 0.16 0.799 0.249 2.47 0.624 0.497 0.21 0.678 1.87 0.711 5.23 0.0399 0.497 0.936 0.029 1.04 0.394 2.78 PRS_PLINK_0.000199526231496888 TRUE 496 Chronic airway obstruction Both 26 208 9 respiratory coral4 208, 26 52, 5 52, 6 52, 7 52, 8 0.0493 0.204 0.81 0.092 1.05 0.697 1.59 0.238 0.597 0.69 0.161 1.27 0.378 4.41 0.099 0.579 0.864 0.063 1.1 0.336 3.71 0.396 0.566 0.484 0.315 1.49 0.478 4.94 PRS_PLINK_0.000199526231496888 TRUE 496.1 Emphysema Both 8 98 9 respiratory coral4 98, 8 25, 1 24, 1 24, 2 25, 4 0.375 0.355 0.291 0.536 1.45 0.707 3.39 0.0939 1.18 0.937 0.028 1.1 0.0239 307 0.779 1.26 0.537 0.27 2.18 0.0966 438 1.13 0.94 0.231 0.637 3.08 0.499 51.2 PRS_PLINK_0.000199526231496888 TRUE 496.2 Chronic bronchitis Both 22 180 9 respiratory coral4 180, 22 45, 4 45, 6 45, 5 45, 7 0.0676 0.224 0.763 0.118 1.07 0.68 1.69 0.233 0.62 0.708 0.15 1.26 0.361 4.67 0.119 0.641 0.853 0.069 1.13 0.3 4.44 0.489 0.615 0.427 0.369 1.63 0.474 6.29 PRS_PLINK_0.000199526231496888 TRUE 496.21 Obstructive chronic bronchitis Both 20 157 9 respiratory coral4 157, 20 40, 4 39, 6 39, 4 39, 6 0.0777 0.23 0.736 0.133 1.08 0.68 1.73 0.22 0.628 0.727 0.139 1.25 0.353 4.62 -0.0612 0.691 0.929 0.032 0.941 0.222 4.08 0.551 0.628 0.38 0.42 1.74 0.498 6.82 PRS_PLINK_0.000199526231496888 TRUE 496.3 Bronchiectasis Both 3 32 9 respiratory coral4 32, 3 8, 0 8, 0 8, 1 8, 2 1.25 0.776 0.107 0.972 3.5 0.866 103 0.661 1.6 0.679 0.168 1.94 0.0104 73.1 1.07 1.4 0.444 0.352 2.91 0.247 129 PRS_PLINK_0.000199526231496888 TRUE 497 Bronchitis Both 25 157 9 respiratory coral4 157, 25 40, 6 39, 6 39, 7 39, 6 0.00205 0.225 0.993 0.003 1 0.636 1.57 0.171 0.658 0.795 0.1 1.19 0.315 4.64 0.407 0.655 0.534 0.272 1.5 0.401 5.9 -0.0487 0.702 0.945 0.025 0.953 0.222 3.96 PRS_PLINK_0.000199526231496888 TRUE 498 Acute bronchospasm Both 13 51 9 respiratory coral4 51, 13 13, 4 13, 2 12, 6 13, 1 -0.614 0.402 0.126 0.898 0.541 0.227 1.13 0.631 1.34 0.637 0.196 1.88 0.0494 31.1 0.105 0.906 0.908 0.042 1.11 0.199 6.16 -2.51 1.63 0.123 0.912 0.0812 0.000282 1.18 PRS_PLINK_0.000199526231496888 TRUE 499 Cystic fibrosis Both 5 22 9 respiratory coral4 22, 5 6, 1 5, 0 5, 3 6, 1 0.027 0.578 0.963 0.016 1.03 0.314 3.16 0.68 20.6 0.974 0.012 1.97 0.00308 1360 -1.48 2.46 0.546 0.263 0.227 0.000801 16.5 2.47 3.65 0.499 0.302 11.8 0.0744 85900 PRS_PLINK_0.000199526231496888 TRUE 500 Lung disease due to external agents Both 3 39 9 respiratory coral4 39, 3 10, 0 10, 0 9, 1 10, 2 0.831 0.621 0.181 0.743 2.3 0.775 20.2 0.247 1.42 0.862 0.065 1.28 0.044 58.8 1.7 1.85 0.359 0.446 5.49 0.164 56900 PRS_PLINK_0.000199526231496888 TRUE 500.1 Extrinsic allergic alveolitis Both 1 3 9 respiratory coral4 3, 1 1, 0 1, 0 1, 1 1, 0 -0.0555 2450 1 0 0.946 0.491 1.18 0.0215 126 1 0 1.02 0.83 1.16 PRS_PLINK_0.000199526231496888 TRUE 500.2 Pneumoconiosis Both 0 2 9 respiratory coral4 2, 0 1 1 1 1 PRS_PLINK_0.000199526231496888 TRUE 501 Pneumonitis due to inhalation of food or vomitus Both 2 32 9 respiratory coral4 32, 2 8, 2 8, 0 8, 0 8, 0 -0.126 0.546 0.818 0.087 0.882 0.0894 8.55 -1.78 2.48 0.473 0.325 0.169 0.000591 15 0.00322 1.85 0.999 0.001 1 0.000291 146 -0.358 1.83 0.845 0.073 0.699 3.11e-07 21000 PRS_PLINK_0.000199526231496888 TRUE 502 Postinflammatory pulmonary fibrosis Both 7 46 9 respiratory coral4 46, 7 12, 2 11, 1 11, 1 12, 3 0.391 0.393 0.32 0.495 1.48 0.7 3.47 0.415 1.23 0.736 0.133 1.51 0.124 46 -0.118 1.26 0.925 0.034 0.888 0.0577 13.4 0.356 0.949 0.708 0.15 1.43 0.254 9.16 PRS_PLINK_0.000199526231496888 TRUE 503 Pulmonary congestion and hypostasis Both 6 61 9 respiratory coral4 61, 6 15, 2 15, 3 15, 1 15, 0 0.348 0.602 0.563 0.249 1.42 0.393 18.8 1.35 1.5 0.37 0.432 3.85 0.262 311 -0.384 1.42 0.786 0.104 0.681 0.000151 136 -0.0899 1.43 0.95 0.022 0.914 1.38e-05 234 PRS_PLINK_0.000199526231496888 TRUE 504 Other alveolar and parietoalveolar pneumonopathy Both 3 24 9 respiratory coral4 24, 3 6, 1 6, 0 6, 1 6, 1 0.127 0.511 0.803 0.095 1.14 0.113 3.15 0.458 1.76 0.794 0.1 1.58 0.0479 226 -0.777 3.21 0.809 0.092 0.46 1.05e-10 117 0.012 1.64 0.994 0.003 1.01 0.101 16.3 PRS_PLINK_0.000199526231496888 TRUE 504.1 Idiopathic fibrosing alveolitis Both 2 9 9 respiratory coral4 9, 2 3, 1 2, 0 2, 1 2, 0 0.454 0.795 0.568 0.245 1.57 0.53 1.64 0.00297 535 1 0 1 0.0194 172 0.356 1910 1 0 1.43 0.504 5.61 0.0397 1790 1 0 1.04 0.719 1.56 PRS_PLINK_0.000199526231496888 TRUE 505 Other pulmonary inflamation or edema Both 19 98 9 respiratory coral4 98, 19 25, 6 24, 5 24, 7 25, 1 -0.291 0.249 0.243 0.615 0.748 0.453 1.21 -0.127 0.643 0.843 0.074 0.88 0.252 3 -0.042 0.656 0.949 0.023 0.959 0.272 3.38 -1.54 0.89 0.0837 1.077 0.215 0.0224 1.09 PRS_PLINK_0.000199526231496888 TRUE 506 Empyema and pneumothorax Both 19 159 9 respiratory coral4 159, 19 40, 4 40, 6 39, 7 40, 2 -0.0924 0.236 0.696 0.157 0.912 0.56 1.47 0.521 0.66 0.43 0.367 1.68 0.461 6.85 0.619 0.683 0.365 0.438 1.86 0.492 8.44 -1.14 0.993 0.251 0.6 0.32 0.00586 2.14 PRS_PLINK_0.000199526231496888 TRUE 507 Pleurisy; pleural effusion Both 26 173 9 respiratory coral4 173, 26 44, 8 43, 4 43, 9 43, 5 -0.12 0.208 0.565 0.248 0.887 0.586 1.35 -0.629 0.598 0.293 0.533 0.533 0.148 1.7 0.0781 0.539 0.885 0.053 1.08 0.371 3.19 -0.491 0.584 0.4 0.398 0.612 0.182 1.89 PRS_PLINK_0.000199526231496888 TRUE 508 Pulmonary collapse; interstitial and compensatory emphysema Both 19 146 9 respiratory coral4 146, 19 37, 3 36, 6 36, 9 37, 1 0.17 0.269 0.529 0.277 1.18 0.697 2.09 0.654 0.706 0.354 0.451 1.92 0.479 9.06 1.81 0.864 0.0361 1.443 6.12 1.29 47.9 -0.197 0.903 0.827 0.082 0.821 0.0853 5.43 PRS_PLINK_0.000199526231496888 TRUE 509 Respiratory failure, insufficiency, arrest Both 28 199 9 respiratory coral4 199, 28 50, 11 50, 2 49, 11 50, 4 0.0119 0.209 0.955 0.02 1.01 0.664 1.54 -1.51 0.743 0.0424 1.372 0.221 0.0375 0.867 0.183 0.518 0.724 0.14 1.2 0.437 3.36 -0.705 0.605 0.244 0.612 0.494 0.134 1.59 PRS_PLINK_0.000199526231496888 TRUE 509.1 Respiratory failure Both 14 111 9 respiratory coral4 111, 14 28, 3 28, 5 27, 6 28, 0 -0.273 0.319 0.391 0.408 0.761 0.391 1.46 1.26 0.955 0.186 0.73 3.53 0.568 34.8 0.726 0.872 0.405 0.392 2.07 0.38 18.9 -0.531 1.15 0.646 0.19 0.588 0.00581 14.5 PRS_PLINK_0.000199526231496888 TRUE 509.2 Respiratory insufficiency Both 10 74 9 respiratory coral4 74, 10 19, 1 18, 2 18, 3 19, 4 0.651 0.351 0.0637 1.196 1.92 0.955 4.05 3.77 2.28 0.0986 1.006 43.5 0.747 83200000 0.0819 1.36 0.952 0.021 1.09 0.0134 21.7 1.23 1.2 0.308 0.511 3.41 0.316 68.5 PRS_PLINK_0.000199526231496888 TRUE 509.3 Pulmonary insufficiency or respiratory failure following trauma and surgery Both 8 85 9 respiratory coral4 85, 8 22, 2 21, 1 21, 3 21, 2 0.535 0.404 0.186 0.731 1.71 0.744 4.92 0.847 1.17 0.469 0.329 2.33 0.182 114 2.03 1.55 0.19 0.722 7.62 0.286 4420000 1.55 1.32 0.242 0.617 4.71 0.314 89000 PRS_PLINK_0.000199526231496888 TRUE 509.8 Dependence on respirator [Ventilator] or supplemental oxygen Both 12 98 9 respiratory coral4 98, 12 25, 7 24, 0 24, 3 25, 2 -0.359 0.323 0.266 0.575 0.698 0.356 1.34 -2.49 1.24 0.0447 1.35 0.0833 0.00071 0.697 -0.943 0.848 0.266 0.575 0.389 0.0555 1.99 -1.11 0.814 0.173 0.762 0.33 0.0524 1.48 PRS_PLINK_0.000199526231496888 TRUE 510 Other diseases of lung Both 69 282 9 respiratory coral4 282, 69 70, 16 70, 9 70, 24 71, 20 0.182 0.141 0.196 0.707 1.2 0.912 1.58 -0.352 0.481 0.464 0.333 0.703 0.264 1.79 0.52 0.384 0.175 0.756 1.68 0.804 3.62 0.474 0.403 0.24 0.62 1.61 0.741 3.57 PRS_PLINK_0.000199526231496888 FALSE 510.2 Lung transplant Both 2 7 9 respiratory coral4 7, 2 2, 0 2, 0 1, 1 2, 1 -0.711 72.4 0.992 0.003 0.491 0.469 0.514 8.05 4950000 1 0 3130 1.43e-10 3.31e+13 0.395 2170 1 0 1.48 0.376 19.1 PRS_PLINK_0.000199526231496888 TRUE 512 Other symptoms of respiratory system Both 267 186 9 respiratory coral4 186, 267 47, 70 46, 46 46, 78 47, 72 -0.00122 0.101 0.99 0.004 0.999 0.82 1.22 -0.413 0.304 0.175 0.757 0.662 0.367 1.19 0.0931 0.283 0.742 0.129 1.1 0.634 1.9 -0.0421 0.29 0.884 0.053 0.959 0.547 1.68 PRS_PLINK_0.000199526231496888 FALSE 512.1 Wheezing Both 24 78 9 respiratory coral4 78, 24 20, 9 19, 5 19, 5 20, 5 -0.348 0.273 0.201 0.697 0.706 0.409 1.17 -0.128 0.698 0.854 0.068 0.88 0.229 3.29 -0.727 0.822 0.376 0.424 0.483 0.0905 2.14 -0.915 0.804 0.255 0.593 0.4 0.0766 1.69 PRS_PLINK_0.000199526231496888 TRUE 512.2 Painful respiration Both 50 140 9 respiratory coral4 140, 50 35, 12 35, 12 35, 17 35, 9 -0.109 0.197 0.58 0.237 0.897 0.611 1.31 -0.00153 0.507 0.998 0.001 0.998 0.375 2.63 0.391 0.503 0.437 0.359 1.48 0.564 3.98 -0.592 0.62 0.339 0.47 0.553 0.158 1.75 PRS_PLINK_0.000199526231496888 TRUE 512.3 Abnormal chest sounds Both 0 7 9 respiratory coral4 7, 0 2 2 1 2 PRS_PLINK_0.000199526231496888 TRUE 512.7 Shortness of breath Both 131 186 9 respiratory coral4 186, 131 47, 35 46, 27 46, 35 47, 34 -0.0121 0.129 0.925 0.034 0.988 0.769 1.27 -0.157 0.363 0.666 0.176 0.855 0.424 1.71 -0.0894 0.344 0.795 0.1 0.914 0.471 1.77 -0.0751 0.359 0.834 0.079 0.928 0.463 1.84 PRS_PLINK_0.000199526231496888 FALSE 512.8 Cough Both 176 186 9 respiratory coral4 186, 176 47, 46 46, 33 46, 48 47, 49 0.0266 0.118 0.821 0.085 1.03 0.818 1.29 -0.265 0.346 0.443 0.354 0.767 0.392 1.49 -0.0159 0.323 0.961 0.017 0.984 0.528 1.83 -0.00214 0.329 0.995 0.002 0.998 0.53 1.88 PRS_PLINK_0.000199526231496888 FALSE 512.9 Other dyspnea Both 137 186 9 respiratory coral4 186, 137 47, 38 46, 26 46, 38 47, 34 -0.0788 0.123 0.522 0.283 0.924 0.728 1.17 -0.411 0.376 0.274 0.562 0.663 0.318 1.35 -0.212 0.346 0.54 0.267 0.809 0.413 1.57 -0.126 0.351 0.719 0.143 0.881 0.449 1.72 PRS_PLINK_0.000199526231496888 FALSE 513 Respiratory abnormalities Both 169 284 9 respiratory coral4 284, 169 71, 48 71, 44 71, 38 71, 38 -0.0995 0.103 0.336 0.474 0.905 0.74 1.11 -0.0418 0.283 0.882 0.054 0.959 0.556 1.65 -0.247 0.299 0.41 0.388 0.781 0.437 1.39 -0.252 0.304 0.406 0.391 0.777 0.431 1.39 PRS_PLINK_0.000199526231496888 FALSE 513.3 Hypoventilation Both 15 68 9 respiratory coral4 68, 15 17, 4 17, 6 17, 4 17, 1 -0.0975 0.444 0.826 0.083 0.907 0.366 2.22 0.963 0.881 0.275 0.561 2.62 0.531 17.3 -0.0673 0.98 0.945 0.024 0.935 0.118 7.09 -1.02 1.41 0.469 0.328 0.359 0.0155 5.33 PRS_PLINK_0.000199526231496888 TRUE 513.31 Apnea Both 8 38 9 respiratory coral4 38, 8 10, 1 9, 3 9, 3 10, 1 0.411 0.706 0.56 0.252 1.51 0.354 13.2 -0.0246 1.76 0.989 0.005 0.976 0.00606 123 1.01 1.44 0.482 0.317 2.75 0.134 75.3 0.107 1.76 0.951 0.022 1.11 0.00232 465 PRS_PLINK_0.000199526231496888 TRUE 513.32 Orthopnea Both 3 11 9 respiratory coral4 11, 3 3, 1 3, 2 2, 0 3, 0 -0.724 1.88 0.7 0.155 0.485 0.427 7.34 4.54 8.55 0.595 0.225 93.7 0.00182 120 -0.0909 2920 1 0 0.913 0.125 2.62 0.00333 121 1 0 1 0.875 1.16 PRS_PLINK_0.000199526231496888 TRUE 513.4 Hyperventilation Both 2 31 9 respiratory coral4 31, 2 8, 1 8, 0 7, 0 8, 1 0.0775 0.575 0.893 0.049 1.08 0.306 3.89 -0.842 1.89 0.655 0.184 0.431 6.09e-07 9.1 -1.1 2.4 0.645 0.19 0.331 3.14e-05 30.3 0.334 1.35 0.804 0.095 1.4 0.0946 27.3 PRS_PLINK_0.000199526231496888 TRUE 513.8 Disorders of diaphragm Both 2 9 9 respiratory coral4 9, 2 3, 0 2, 0 2, 1 2, 1 0.351 1.97 0.858 0.066 1.42 1.31 1.52 -0.303 7010 1 0 0.739 0.555 1.59 0.0369 1040 1 0 1.04 0.682 2.37 PRS_PLINK_0.000199526231496888 TRUE 514 Abnormal findings examination of lungs Both 31 281 9 respiratory coral4 281, 31 70, 15 70, 10 70, 1 70, 5 -0.482 0.195 0.0133 1.876 0.618 0.415 0.906 -0.39 0.448 0.384 0.415 0.677 0.273 1.62 -2.24 0.814 0.00582 2.235 0.106 0.0113 0.46 -0.837 0.528 0.113 0.947 0.433 0.138 1.19 PRS_PLINK_0.000199526231496888 TRUE 514.1 Abnormal results of function study of pulmonary system Both 5 17 9 respiratory coral4 17, 5 5, 2 4, 1 4, 2 4, 0 0.447 1.12 0.69 0.161 1.56 0.229 14.1 1.2 2.16 0.578 0.238 3.32 0.089 855 2.37 4.71 0.614 0.211 10.7 0.00965 1.14e+09 4.6 233 0.984 0.007 99.6 74.5 133 PRS_PLINK_0.000199526231496888 TRUE 514.2 Solitary pulmonary nodule Both 22 186 9 respiratory coral4 186, 22 46, 9 46, 5 46, 2 47, 6 -0.286 0.234 0.222 0.653 0.751 0.464 1.19 -0.328 0.6 0.584 0.233 0.72 0.211 2.32 -1.52 0.798 0.0566 1.247 0.218 0.0317 0.997 -0.13 0.611 0.831 0.08 0.878 0.246 3.01 PRS_PLINK_0.000199526231496888 TRUE 516 Abnormal sputum Both 9 58 9 respiratory coral4 58, 9 15, 0 14, 2 14, 4 15, 3 0.553 0.403 0.17 0.77 1.74 0.809 4.09 1.54 1.35 0.255 0.594 4.65 0.387 4150 5.16 3.38 0.126 0.898 174 0.429 1.05e+13 1.03 1.55 0.506 0.296 2.81 0.0223 352 PRS_PLINK_0.000199526231496888 TRUE 516.1 Hemoptysis Both 7 46 9 respiratory coral4 46, 7 12, 0 11, 1 11, 4 12, 2 0.318 0.456 0.486 0.314 1.37 0.581 3.48 0.762 1.38 0.582 0.235 2.14 0.157 598 2.37 2.24 0.288 0.54 10.7 0.29 87700 1.6 1.96 0.413 0.384 4.97 0.0189 1300 PRS_PLINK_0.000199526231496888 TRUE 519 Other diseases of respiratory system, not elsewhere classified Both 75 360 9 respiratory coral4 360, 75 90, 26 90, 18 90, 14 90, 16 -0.278 0.135 0.0398 1.4 0.757 0.58 0.984 -0.336 0.364 0.356 0.449 0.715 0.348 1.45 -0.767 0.388 0.0478 1.321 0.464 0.211 0.978 -0.544 0.37 0.141 0.849 0.581 0.277 1.18 PRS_PLINK_0.000199526231496888 FALSE 519.1 Tracheostomy complications Both 1 12 9 respiratory coral4 12, 1 3, 1 3, 0 3, 0 3, 0 -0.149 1.16 0.898 0.047 0.862 0.0553 23.7 -0.0147 2340 1 0 0.985 0.565 1.67 0.0988 3720 1 0 1.1 0.386 1.15 -0.174 3530000 1 0 0.84 0.548 3.03 PRS_PLINK_0.000199526231496888 TRUE 519.2 Respiratory complications Both 1 27 9 respiratory coral4 27, 1 7, 0 7, 0 6, 1 7, 0 -0.0307 0.83 0.971 0.013 0.97 0.0827 27.2 0.099 3.4 0.977 0.01 1.1 0.0104 141 PRS_PLINK_0.000199526231496888 TRUE 519.8 Other diseases of respiratory system, NEC Both 20 131 9 respiratory coral4 131, 20 33, 10 33, 2 32, 4 33, 3 -0.651 0.259 0.012 1.92 0.522 0.303 0.856 -1.37 0.723 0.0575 1.24 0.253 0.045 0.984 -0.804 0.649 0.215 0.667 0.447 0.112 1.51 -1.11 0.663 0.0936 1.029 0.329 0.0726 1.14 PRS_PLINK_0.000199526231496888 TRUE 519.9 Symptoms involving respiratory system and other chest symptoms Both 48 276 9 respiratory coral4 276, 48 69, 19 69, 7 69, 9 69, 13 -0.193 0.165 0.241 0.619 0.824 0.594 1.14 -0.892 0.489 0.0681 1.167 0.41 0.147 1.04 -0.756 0.456 0.0971 1.013 0.47 0.184 1.12 -0.478 0.418 0.253 0.597 0.62 0.268 1.39 PRS_PLINK_0.000199526231496888 TRUE 520 Disorders of tooth development Both 5 36 10 digestive chartreuse4 36, 5 9, 2 9, 1 9, 0 9, 2 -0.48 0.46 0.297 0.527 0.619 0.224 1.47 -0.215 1.22 0.86 0.066 0.806 0.0758 19.4 -1.13 1.26 0.372 0.429 0.324 0.00822 2.75 -0.272 1.25 0.828 0.082 0.762 0.0617 11 PRS_PLINK_0.000199526231496888 TRUE 520.1 Hereditary disturbances in tooth structure Both 1 18 10 digestive chartreuse4 18, 1 5, 0 4, 0 4, 0 5, 1 0.0312 1.07 0.977 0.01 1.03 0.0149 55.5 -0.291 4.23 0.945 0.024 0.748 1.64e-05 547 PRS_PLINK_0.000199526231496888 TRUE 520.2 Disturbances in tooth eruption Both 4 20 10 digestive chartreuse4 20, 4 5, 2 5, 1 5, 1 5, 0 -0.503 0.569 0.376 0.424 0.604 0.179 1.64 -0.918 1.8 0.61 0.215 0.399 0.00141 20.2 0.162 1.74 0.926 0.034 1.18 0.0645 41.8 -1.17 2.64 0.659 0.181 0.312 0.00105 17.7 PRS_PLINK_0.000199526231496888 TRUE 521 Diseases of hard tissues of teeth Both 10 84 10 digestive chartreuse4 84, 10 21, 1 21, 2 21, 5 21, 2 0.14 0.339 0.68 0.167 1.15 0.566 2.33 0.23 1.11 0.835 0.078 1.26 0.124 28 1.01 0.996 0.31 0.509 2.75 0.412 33.7 -0.129 1.04 0.901 0.045 0.879 0.0835 18.8 PRS_PLINK_0.000199526231496888 TRUE 521.1 Dental caries Both 9 74 10 digestive chartreuse4 74, 9 19, 0 18, 4 18, 3 19, 2 0.241 0.361 0.504 0.297 1.27 0.614 2.72 1.46 1.17 0.212 0.674 4.32 0.479 350 1.29 1.15 0.263 0.58 3.64 0.404 199 0.799 1.19 0.502 0.299 2.22 0.2 239 PRS_PLINK_0.000199526231496888 TRUE 521.2 Dental abrasion, erosion and attrition Both 1 6 10 digestive chartreuse4 6, 1 2, 1 1, 0 1, 0 2, 0 -0.242 946 1 0 0.785 0.521 0.683 -0.481 22800 1 0 0.618 0.279 6.67 0.0794 7370 1 0 1.08 0.596 1.26 -0.00642 1050 1 0 0.994 0.779 1.25 PRS_PLINK_0.000199526231496888 TRUE 522 Diseases of pulp and periapical tissues Both 14 57 10 digestive chartreuse4 57, 14 14, 3 14, 5 14, 3 14, 3 0.294 0.343 0.39 0.408 1.34 0.713 2.74 0.154 0.905 0.865 0.063 1.17 0.215 6.4 0.778 1.05 0.461 0.337 2.18 0.319 22.2 1.12 1.13 0.321 0.493 3.06 0.428 43.9 PRS_PLINK_0.000199526231496888 TRUE 522.5 Periapical abscess Both 14 46 10 digestive chartreuse4 46, 14 11, 3 11, 6 11, 2 12, 3 0.261 0.325 0.423 0.374 1.3 0.717 2.52 0.613 0.958 0.522 0.282 1.85 0.349 10.9 0.105 1.12 0.926 0.033 1.11 0.131 18.9 0.785 1.07 0.462 0.335 2.19 0.307 24.8 PRS_PLINK_0.000199526231496888 TRUE 523 Gingival and periodontal diseases Both 15 65 10 digestive chartreuse4 65, 15 16, 4 16, 3 16, 3 16, 5 -0.195 0.336 0.562 0.25 0.823 0.407 1.59 -0.362 0.919 0.693 0.159 0.696 0.112 3.95 -0.309 0.899 0.731 0.136 0.734 0.129 4.01 -1.4 1.21 0.247 0.608 0.246 0.00165 2.26 PRS_PLINK_0.000199526231496888 TRUE 523.1 Gingivitis Both 3 10 10 digestive chartreuse4 10, 3 3, 1 2, 0 2, 0 3, 2 -0.245 3.04 0.936 0.029 0.783 0.000136 155 -0.0604 4520 1 0 0.941 0.283 2.9 -0.0631 4300 1 0 0.939 0.27 3.04 -3.94 509 0.994 0.003 0.0195 0.328 0.214 PRS_PLINK_0.000199526231496888 TRUE 523.3 Periodontitis (acute or chronic) Both 8 43 10 digestive chartreuse4 43, 8 10, 3 11, 2 10, 0 11, 3 -0.122 0.393 0.756 0.122 0.885 0.411 2.03 -0.485 1.08 0.652 0.186 0.616 0.0845 4.08 -1.2 1.37 0.382 0.418 0.302 0.0012 3.5 -0.407 1.02 0.691 0.16 0.666 0.0845 4.04 PRS_PLINK_0.000199526231496888 TRUE 523.31 Acute periodontitis Both 8 41 10 digestive chartreuse4 41, 8 10, 3 10, 2 10, 1 10, 2 -0.0783 0.396 0.843 0.074 0.925 0.442 2.11 -0.452 1.1 0.68 0.167 0.636 0.0862 4.24 -0.767 1.26 0.544 0.265 0.465 0.0116 6.1 0.477 1.57 0.761 0.119 1.61 0.0194 261 PRS_PLINK_0.000199526231496888 TRUE 523.32 Chronic periodontitis Both 2 5 10 digestive chartreuse4 5, 2 2, 1 1, 0 1, 0 1, 1 -0.0845 540 1 0 0.919 0.588 0.95 -0.212 12700 1 0 0.809 0.0507 9.66 -0.0738 4840 1 0 0.929 0.336 2.34 -0.109 5280 1 0 0.897 0.818 2.96 PRS_PLINK_0.000199526231496888 TRUE 524 Dentofacial anomalies, including malocclusion Both 5 43 10 digestive chartreuse4 43, 5 11, 3 11, 0 10, 1 11, 1 -0.406 0.526 0.44 0.356 0.666 0.198 1.94 -2.27 1.9 0.231 0.637 0.103 1.73e-05 3.54 -0.58 1.22 0.636 0.197 0.56 0.0327 5.37 -1.73 1.57 0.269 0.57 0.177 9.79e-10 2.98 PRS_PLINK_0.000199526231496888 TRUE 524.3 Anomalies of tooth position/malocclusion Both 3 27 10 digestive chartreuse4 27, 3 7, 1 7, 0 6, 1 7, 1 0.309 0.601 0.607 0.217 1.36 0.374 5.17 -0.953 1.94 0.623 0.205 0.386 0.000196 10.3 -0.0204 1.56 0.99 0.005 0.98 0.0585 17.6 -2.56 2.54 0.313 0.504 0.0776 3.04e-09 6.89 PRS_PLINK_0.000199526231496888 TRUE 525 Other diseases of the teeth and supporting structures Both 17 85 10 digestive chartreuse4 85, 17 21, 2 21, 2 21, 6 21, 7 0.361 0.275 0.19 0.72 1.43 0.853 2.57 0.109 0.963 0.91 0.041 1.11 0.139 12 0.368 0.817 0.652 0.186 1.45 0.301 8.09 0.911 0.76 0.231 0.637 2.49 0.612 15.1 PRS_PLINK_0.000199526231496888 TRUE 525.1 Loss of teeth or edentulism Both 7 26 10 digestive chartreuse4 26, 7 7, 2 6, 1 6, 2 7, 2 0.313 0.575 0.587 0.231 1.37 0.544 6.71 -1.26 2.01 0.531 0.275 0.283 0.243 6.38 2.4 2.82 0.394 0.405 11.1 0.101 10400000 0.68 1.85 0.713 0.147 1.97 0.0252 11900 PRS_PLINK_0.000199526231496888 TRUE 526 Diseases of the jaws Both 47 298 10 digestive chartreuse4 298, 47 74, 17 74, 10 74, 4 75, 16 -0.152 0.161 0.346 0.46 0.859 0.625 1.18 -0.426 0.441 0.333 0.477 0.653 0.27 1.52 -1.54 0.572 0.00704 2.153 0.214 0.0599 0.622 -0.0698 0.418 0.867 0.062 0.933 0.414 2.1 PRS_PLINK_0.000199526231496888 TRUE 526.1 Cysts of the jaws Both 4 23 10 digestive chartreuse4 23, 4 6, 1 6, 0 5, 1 6, 2 0.114 0.656 0.862 0.065 1.12 0.36 5.18 0.293 1.89 0.877 0.057 1.34 0.0251 7640 2.58 3.23 0.424 0.372 13.2 0.114 201000 -1.21 1.86 0.515 0.288 0.297 7.03e-07 8.85 PRS_PLINK_0.000199526231496888 TRUE 526.3 Anomalies of jaw size/symmetry Both 4 29 10 digestive chartreuse4 29, 4 8, 2 7, 0 7, 1 7, 1 -0.243 0.613 0.692 0.16 0.785 0.202 2.58 -1.39 2.02 0.491 0.309 0.248 1.56e-05 15.6 -1.67 1.89 0.378 0.422 0.189 9.66e-10 3.57 -0.674 1.55 0.664 0.178 0.51 0.0103 8.43 PRS_PLINK_0.000199526231496888 TRUE 526.4 Temporomandibular joint disorders Both 32 194 10 digestive chartreuse4 194, 32 48, 10 48, 9 48, 2 49, 11 -0.111 0.198 0.575 0.24 0.895 0.605 1.32 -0.155 0.521 0.767 0.115 0.857 0.307 2.34 -1.65 0.774 0.033 1.481 0.192 0.0309 0.806 -0.0428 0.535 0.936 0.029 0.958 0.341 2.71 PRS_PLINK_0.000199526231496888 TRUE 526.41 Temporomandibular joint disorder, unspecified Both 26 173 10 digestive chartreuse4 173, 26 43, 10 43, 4 43, 5 43, 7 -0.189 0.208 0.363 0.44 0.827 0.549 1.25 -0.727 0.618 0.239 0.621 0.483 0.133 1.53 -0.702 0.602 0.244 0.613 0.496 0.143 1.58 -0.378 0.597 0.527 0.278 0.685 0.208 2.15 PRS_PLINK_0.000199526231496888 TRUE 526.42 Arthralgia/ankylosis of temporomandibular joint Both 12 107 10 digestive chartreuse4 107, 12 27, 4 27, 3 26, 1 27, 4 -0.234 0.32 0.465 0.333 0.791 0.405 1.5 -0.39 0.877 0.657 0.183 0.677 0.0961 3.99 -1.02 0.977 0.295 0.531 0.359 0.0351 2.35 0.525 0.851 0.537 0.27 1.69 0.326 10 PRS_PLINK_0.000199526231496888 TRUE 526.5 Inflammatory conditions of jaw Both 2 12 10 digestive chartreuse4 12, 2 3, 0 3, 1 3, 0 3, 1 0.299 0.984 0.762 0.118 1.35 0.297 12.9 0.094 3400 1 0 1.1 0.0178 38.1 0.434 3700000 1 0 1.54 0.696 3.93 PRS_PLINK_0.000199526231496888 TRUE 526.8 Exostosis of jaw Both 0 5 10 digestive chartreuse4 5, 0 2 1 1 1 PRS_PLINK_0.000199526231496888 TRUE 526.9 Jaw disease NOS Both 3 42 10 digestive chartreuse4 42, 3 11, 1 10, 2 10, 0 11, 0 -0.4 0.538 0.457 0.34 0.67 0.178 1.93 0.0413 1.24 0.973 0.012 1.04 0.11 21.4 -1.6 1.74 0.357 0.448 0.201 6.3e-05 3.58 -1.53 1.69 0.363 0.44 0.216 0.00204 3.43 PRS_PLINK_0.000199526231496888 TRUE 527 Diseases of the salivary glands Both 23 132 10 digestive chartreuse4 132, 23 32, 7 33, 6 33, 6 33, 4 -0.117 0.236 0.62 0.208 0.89 0.552 1.43 -0.357 0.658 0.588 0.231 0.7 0.182 2.51 -0.22 0.644 0.732 0.135 0.802 0.222 2.81 -0.814 0.734 0.267 0.573 0.443 0.092 1.78 PRS_PLINK_0.000199526231496888 TRUE 527.1 Hypertrophy of salivary gland Both 2 5 10 digestive chartreuse4 5, 2 2, 0 1, 0 1, 1 1, 1 0.226 276000 1 0 1.25 0.852 1.56 0.154 27600 1 0 1.17 0.0576 4.45 -0.154 413 1 0 0.857 0.295 1.38 PRS_PLINK_0.000199526231496888 TRUE 527.2 Sialoadenitis Both 7 40 10 digestive chartreuse4 40, 7 9, 2 10, 0 10, 3 10, 2 -0.11 0.456 0.809 0.092 0.896 0.376 2.35 -1.46 1.96 0.457 0.34 0.232 0.00109 33.3 -0.493 1.45 0.733 0.135 0.611 0.00743 7.85 0.947 1.84 0.606 0.217 2.58 0.0544 1810 PRS_PLINK_0.000199526231496888 TRUE 527.7 Disturbance of salivary secretion Both 13 54 10 digestive chartreuse4 54, 13 14, 2 13, 2 13, 5 14, 4 0.277 0.332 0.405 0.392 1.32 0.703 2.65 -0.574 1.23 0.64 0.194 0.563 0.049 6.24 0.718 0.949 0.449 0.348 2.05 0.385 14 0.276 0.968 0.775 0.111 1.32 0.198 8.92 PRS_PLINK_0.000199526231496888 TRUE 527.8 Other specified diseases of the salivary glands Both 2 20 10 digestive chartreuse4 20, 2 5, 1 5, 0 5, 0 5, 1 -0.32 0.841 0.703 0.153 0.726 0.0322 4.13 -0.518 2.91 0.859 0.066 0.596 9.45e-05 134 -0.617 3.56 0.862 0.064 0.54 0.000208 2110 0.251 2.08 0.904 0.044 1.28 0.01 70.1 PRS_PLINK_0.000199526231496888 TRUE 528 Diseases of the oral soft tissues, excluding lesions specific for gingiva and tongue Both 27 240 10 digestive chartreuse4 240, 27 59, 7 60, 8 60, 6 60, 6 -0.0837 0.203 0.68 0.167 0.92 0.612 1.39 0.297 0.541 0.583 0.234 1.35 0.458 4.16 0.116 0.567 0.838 0.077 1.12 0.345 3.78 0.00536 0.58 0.993 0.003 1.01 0.307 3.26 PRS_PLINK_0.000199526231496888 TRUE 528.1 Stomatitis and mucositis Both 6 62 10 digestive chartreuse4 62, 6 16, 2 15, 1 15, 1 16, 2 -0.187 0.394 0.636 0.197 0.83 0.362 1.87 -1.02 1.2 0.395 0.404 0.359 0.00147 3.33 -0.392 1.11 0.723 0.141 0.676 0.0407 6.08 -1.01 1.34 0.451 0.345 0.363 0.00815 5.01 PRS_PLINK_0.000199526231496888 TRUE 528.11 Stomatitis and mucositis (ulcerative) Both 3 16 10 digestive chartreuse4 16, 3 4, 2 4, 0 4, 1 4, 0 -1.09 1.01 0.281 0.552 0.336 0.00735 1.65 0.469 2.49 0.851 0.07 1.6 0.0101 5670 -0.315 3.24 0.923 0.035 0.73 0.000332 146000 -0.219 1.84 0.905 0.043 0.803 0.014 14 PRS_PLINK_0.000199526231496888 TRUE 528.12 Oral aphthae Both 4 31 10 digestive chartreuse4 31, 4 7, 1 8, 1 7, 0 8, 2 0.17 0.456 0.709 0.15 1.19 0.504 3.12 -0.145 1.77 0.935 0.029 0.865 0.0233 32.8 -0.534 1.63 0.743 0.129 0.586 0.00169 12.3 0.0325 1.4 0.982 0.008 1.03 0.0754 12 PRS_PLINK_0.000199526231496888 TRUE 528.3 Cellulitis and abscess of oral soft tissues Both 3 24 10 digestive chartreuse4 24, 3 6, 0 6, 1 6, 1 6, 1 0.741 0.681 0.277 0.557 2.1 0.624 4370 0.99 2.43 0.684 0.165 2.69 0.0319 459 -0.056 2.56 0.983 0.008 0.946 0.00158 200 0.805 2.02 0.691 0.161 2.24 0.0843 87.5 PRS_PLINK_0.000199526231496888 TRUE 528.4 Cysts of oral soft tissues Both 0 14 10 digestive chartreuse4 14, 0 4 3 3 4 PRS_PLINK_0.000199526231496888 TRUE 528.41 Cyst of the salivary gland Both 0 11 10 digestive chartreuse4 11, 0 3 3 2 3 PRS_PLINK_0.000199526231496888 TRUE 528.5 Diseases of lips Both 6 47 10 digestive chartreuse4 47, 6 11, 1 12, 2 11, 2 12, 1 0.175 0.397 0.659 0.181 1.19 0.544 3.15 -0.0449 1.52 0.976 0.01 0.956 0.00889 39.8 1.36 1.44 0.345 0.462 3.91 0.326 246 -0.905 1.77 0.609 0.216 0.405 3.78e-05 190 PRS_PLINK_0.000199526231496888 TRUE 528.6 Leukoplakia of oral mucosa Both 1 3 10 digestive chartreuse4 3, 1 1, 0 1, 1 1, 0 1, 0 -0.021 2530 1 0 0.979 0.738 1.26 -0.000349 509 1 0 1 0.749 1.18 PRS_PLINK_0.000199526231496888 TRUE 528.7 Sialolithiasis Both 1 16 10 digestive chartreuse4 16, 1 4, 0 4, 0 4, 1 4, 0 0.105 0.81 0.897 0.047 1.11 0.144 5.15 2.54 51.8 0.961 0.017 12.7 0.000373 494000 PRS_PLINK_0.000199526231496888 TRUE 529 Diseases and other conditions of the tongue Both 5 41 10 digestive chartreuse4 41, 5 11, 1 10, 1 10, 0 10, 3 0.765 0.585 0.191 0.719 2.15 0.773 8.92 -0.613 1.59 0.699 0.156 0.542 0.00248 37 -0.37 2.07 0.858 0.066 0.69 0.00506 26.5 0.687 1.4 0.625 0.204 1.99 0.203 30 PRS_PLINK_0.000199526231496888 TRUE 529.1 Glossitis Both 1 9 10 digestive chartreuse4 9, 1 3, 0 2, 0 2, 0 2, 1 -0.395 58 0.995 0.002 0.674 0.657 0.691 0.00283 194 1 0 1 0.78 1.35 PRS_PLINK_0.000199526231496888 TRUE 529.6 Glossodynia Both 2 11 10 digestive chartreuse4 11, 2 3, 1 3, 0 2, 0 3, 1 -0.0789 1.03 0.939 0.028 0.924 0.0896 57.6 0.0843 445 1 0 1.09 0.767 2.35 0.0491 718 1 0 1.05 0.859 1.12 -0.0574 22.2 0.998 0.001 0.944 0.49 0.43 PRS_PLINK_0.000199526231496888 TRUE 530 Diseases of esophagus Both 207 231 10 digestive chartreuse4 231, 207 58, 74 58, 55 57, 38 58, 39 -0.241 0.102 0.0181 1.743 0.786 0.644 0.956 -0.279 0.271 0.304 0.517 0.757 0.449 1.27 -0.618 0.291 0.0334 1.476 0.539 0.307 0.938 -0.66 0.294 0.025 1.602 0.517 0.292 0.904 PRS_PLINK_0.000199526231496888 FALSE 530.1 Esophagitis, GERD and related diseases Both 204 231 10 digestive chartreuse4 231, 204 58, 73 58, 54 57, 38 58, 38 -0.24 0.102 0.0189 1.723 0.787 0.644 0.957 -0.284 0.272 0.296 0.528 0.753 0.446 1.27 -0.614 0.291 0.0345 1.462 0.541 0.308 0.941 -0.656 0.294 0.0257 1.589 0.519 0.294 0.907 PRS_PLINK_0.000199526231496888 FALSE 530.11 GERD Both 201 231 10 digestive chartreuse4 231, 201 58, 73 58, 52 57, 38 58, 37 -0.249 0.102 0.0152 1.817 0.78 0.638 0.949 -0.325 0.274 0.234 0.631 0.722 0.426 1.22 -0.614 0.291 0.0345 1.462 0.541 0.308 0.941 -0.694 0.296 0.0191 1.72 0.5 0.281 0.876 PRS_PLINK_0.000199526231496888 FALSE 530.12 Ulcer of esophagus Both 7 18 10 digestive chartreuse4 18, 7 5, 2 4, 1 4, 4 5, 0 -0.383 0.807 0.635 0.197 0.682 0.129 2.88 -0.204 2.9 0.944 0.025 0.815 0.00607 7120 0.572 1.52 0.706 0.151 1.77 0.151 21.8 -0.303 3.32 0.927 0.033 0.738 0.00219 255000 PRS_PLINK_0.000199526231496888 TRUE 530.13 Barrett's esophagus Both 6 40 10 digestive chartreuse4 40, 6 10, 1 10, 3 10, 1 10, 1 -0.246 0.461 0.594 0.226 0.782 0.31 1.96 0.989 1.41 0.482 0.317 2.69 0.23 193 -0.923 1.55 0.552 0.258 0.397 0.00464 9.04 -0.109 1.76 0.951 0.022 0.897 0.00286 127 PRS_PLINK_0.000199526231496888 TRUE 530.14 Reflux esophagitis Both 38 127 10 digestive chartreuse4 127, 38 32, 6 32, 12 31, 11 32, 9 0.163 0.195 0.402 0.396 1.18 0.812 1.73 0.737 0.623 0.237 0.625 2.09 0.648 7.32 0.822 0.606 0.175 0.757 2.27 0.74 7.72 0.431 0.595 0.469 0.329 1.54 0.503 4.96 PRS_PLINK_0.000199526231496888 TRUE 530.15 Eosinophilic esophagitis Both 6 24 10 digestive chartreuse4 24, 6 6, 1 6, 0 6, 1 6, 4 1.15 0.727 0.113 0.946 3.16 0.941 15.3 0.304 2.28 0.894 0.049 1.36 0.0097 262 0.651 1.59 0.683 0.166 1.92 0.12 34.5 1.5 2.4 0.531 0.275 4.49 0.0471 1340 PRS_PLINK_0.000199526231496888 TRUE 530.2 Esophageal bleeding (varices/hemorrhage) Both 7 23 10 digestive chartreuse4 23, 7 6, 1 6, 0 5, 2 6, 4 0.679 0.687 0.323 0.491 1.97 0.536 36.5 -0.694 1.94 0.72 0.143 0.5 0.000958 42.7 0.557 1.55 0.72 0.142 1.74 0.0628 42.1 1.06 1.7 0.532 0.274 2.89 0.117 431000 PRS_PLINK_0.000199526231496888 TRUE 530.3 Stricture and stenosis of esophagus Both 10 48 10 digestive chartreuse4 48, 10 12, 2 12, 1 12, 5 12, 2 0.216 0.332 0.515 0.288 1.24 0.669 2.43 -0.0894 1.12 0.936 0.029 0.914 0.0973 8.59 0.519 1.08 0.631 0.2 1.68 0.258 15.2 0.179 1.19 0.88 0.055 1.2 0.082 34.2 PRS_PLINK_0.000199526231496888 TRUE 530.5 Disorders of esophageal motility Both 4 38 10 digestive chartreuse4 38, 4 10, 0 9, 0 9, 1 10, 3 0.686 0.523 0.189 0.722 1.99 0.762 8.76 1.48 1.69 0.381 0.419 4.38 0.115 324 1.7 1.83 0.354 0.451 5.46 0.0819 8670000 PRS_PLINK_0.000199526231496888 TRUE 530.6 Diverticulum of esophagus, acquired Both 0 7 10 digestive chartreuse4 7, 0 2 2 1 2 PRS_PLINK_0.000199526231496888 TRUE 530.7 Gastroesophageal laceration-hemorrhage syndrome Both 4 4 10 digestive chartreuse4 4, 4 1, 1 1, 0 1, 1 1, 2 -0.204 3030000 1 0 0.816 0.108 10 -0.848 7680000 1 0 0.428 0.000567 116 0.0468 4650 1 0 1.05 0.766 2.46 -0.354 2600 1 0 0.702 0.0729 8.14 PRS_PLINK_0.000199526231496888 TRUE 530.9 Heartburn Both 30 120 10 digestive chartreuse4 120, 30 30, 7 30, 9 30, 9 30, 5 0.0285 0.207 0.89 0.05 1.03 0.687 1.54 0.436 0.655 0.506 0.296 1.55 0.45 5.69 0.248 0.571 0.664 0.178 1.28 0.43 3.89 -0.392 0.665 0.556 0.255 0.676 0.179 2.35 PRS_PLINK_0.000199526231496888 TRUE 531 Peptic ulcer (excl. esophageal) Both 26 181 10 digestive chartreuse4 181, 26 46, 5 45, 8 45, 8 45, 5 0.0814 0.221 0.713 0.147 1.08 0.7 1.69 0.583 0.64 0.362 0.441 1.79 0.526 6.79 0.376 0.594 0.527 0.278 1.46 0.452 5.06 0.169 0.636 0.791 0.102 1.18 0.325 4.41 PRS_PLINK_0.000199526231496888 TRUE 531.1 Hemorrhage from gastrointestinal ulcer Both 5 31 10 digestive chartreuse4 31, 5 8, 0 8, 1 7, 0 8, 4 0.517 0.653 0.429 0.368 1.68 0.415 13.2 -0.5 2.17 0.818 0.087 0.606 0.0027 38.3 0.701 1.61 0.664 0.178 2.02 0.0564 320 PRS_PLINK_0.000199526231496888 TRUE 531.2 Gastric ulcer Both 17 114 10 digestive chartreuse4 114, 17 29, 2 28, 7 28, 5 29, 3 0.0663 0.272 0.807 0.093 1.07 0.619 1.83 1.39 0.903 0.124 0.906 4.01 0.754 36.9 1.43 0.971 0.14 0.854 4.19 0.688 49 0.569 0.901 0.528 0.278 1.77 0.254 18.3 PRS_PLINK_0.000199526231496888 TRUE 531.3 Duodenal ulcer Both 7 37 10 digestive chartreuse4 37, 7 10, 1 9, 1 9, 3 9, 2 0.178 0.404 0.659 0.181 1.2 0.575 2.68 -0.397 2.01 0.844 0.074 0.673 0.000277 2660 0.796 1.37 0.561 0.251 2.22 0.182 51.5 0.501 1.26 0.692 0.16 1.65 0.156 95.6 PRS_PLINK_0.000199526231496888 TRUE 531.4 Peptic ulcer, site unspecified Both 17 81 10 digestive chartreuse4 81, 17 21, 6 20, 1 20, 5 20, 5 0.126 0.304 0.679 0.168 1.13 0.617 2.11 -1.35 1.07 0.206 0.686 0.258 0.0153 1.73 -0.156 0.692 0.821 0.085 0.855 0.225 3.19 -0.213 0.728 0.77 0.114 0.808 0.193 3.22 PRS_PLINK_0.000199526231496888 TRUE 531.5 Gastrojejunal ulcer Both 2 20 10 digestive chartreuse4 20, 2 5, 1 5, 0 5, 0 5, 1 0.458 0.823 0.578 0.238 1.58 0.234 19.2 -0.87 2.94 0.767 0.115 0.419 0.387 0.457 0.115 2.67 0.966 0.015 1.12 3.4e-06 1090 1.62 2.22 0.467 0.331 5.05 0.0953 1080 PRS_PLINK_0.000199526231496888 TRUE 532 Dysphagia Both 53 224 10 digestive chartreuse4 224, 53 56, 17 56, 11 56, 12 56, 13 -0.141 0.156 0.365 0.438 0.868 0.641 1.18 -0.389 0.447 0.385 0.415 0.678 0.277 1.6 -0.226 0.43 0.599 0.223 0.798 0.34 1.83 -0.212 0.455 0.642 0.193 0.809 0.332 1.92 PRS_PLINK_0.000199526231496888 FALSE 535 Gastritis and duodenitis Both 35 242 10 digestive chartreuse4 242, 35 60, 6 60, 10 60, 12 61, 7 0.127 0.19 0.503 0.298 1.14 0.781 1.67 0.944 0.607 0.12 0.922 2.57 0.799 9.4 0.641 0.522 0.22 0.658 1.9 0.694 5.64 0.26 0.57 0.649 0.188 1.3 0.41 4.31 PRS_PLINK_0.000199526231496888 TRUE 535.1 Acute gastritis Both 18 101 10 digestive chartreuse4 101, 18 26, 3 25, 6 25, 6 25, 3 0.0449 0.269 0.867 0.062 1.05 0.618 1.82 1.16 0.938 0.218 0.662 3.18 0.566 24.9 1.18 0.854 0.166 0.781 3.27 0.657 25 0.166 0.863 0.847 0.072 1.18 0.218 6.62 PRS_PLINK_0.000199526231496888 TRUE 535.2 Atrophic gastritis Both 6 36 10 digestive chartreuse4 36, 6 8, 0 9, 2 9, 3 9, 1 -0.789 0.651 0.226 0.646 0.454 0.05 2.67 0.0407 1.83 0.982 0.008 1.04 0.00306 135 -0.766 2.12 0.718 0.144 0.465 4.02e-05 54.9 -0.338 2.91 0.908 0.042 0.714 3.94e-05 986 PRS_PLINK_0.000199526231496888 TRUE 535.6 Duodenitis Both 1 28 10 digestive chartreuse4 28, 1 7, 0 7, 0 7, 0 7, 1 0.267 0.816 0.743 0.129 1.31 0.21 12.9 0.661 1.83 0.718 0.144 1.94 0.0869 48.8 PRS_PLINK_0.000199526231496888 TRUE 535.8 Other specified gastritis Both 11 52 10 digestive chartreuse4 52, 11 13, 2 13, 2 13, 5 13, 2 -0.62 0.482 0.198 0.703 0.538 0.179 1.31 -0.14 1.04 0.892 0.049 0.869 0.126 6.29 0.0272 1.11 0.98 0.009 1.03 0.121 9.49 -0.589 1.27 0.642 0.192 0.555 0.0303 6.92 PRS_PLINK_0.000199526231496888 TRUE 535.9 Gastritis and duodenitis, NOS Both 14 120 10 digestive chartreuse4 120, 14 29, 2 30, 3 30, 5 30, 4 0.313 0.289 0.279 0.555 1.37 0.753 2.61 -0.575 0.946 0.543 0.265 0.563 0.0365 4.92 0.19 0.825 0.818 0.087 1.21 0.21 7.98 0.374 0.773 0.629 0.201 1.45 0.292 9.69 PRS_PLINK_0.000199526231496888 TRUE 536 Disorders of function of stomach Both 43 268 10 digestive chartreuse4 268, 43 67, 11 67, 14 67, 5 67, 13 0.0313 0.168 0.852 0.07 1.03 0.739 1.44 0.126 0.461 0.784 0.106 1.13 0.458 2.83 -0.578 0.546 0.29 0.538 0.561 0.174 1.63 0.47 0.462 0.308 0.511 1.6 0.645 4.05 PRS_PLINK_0.000199526231496888 TRUE 536.3 Gastroparesis Both 7 62 10 digestive chartreuse4 62, 7 16, 2 15, 1 15, 1 16, 3 0.505 0.424 0.234 0.632 1.66 0.726 9.03 -0.674 1.44 0.641 0.193 0.51 0.000156 45 -0.0159 1.43 0.991 0.004 0.984 0.0152 418 0.775 1.04 0.457 0.34 2.17 0.271 3.11 PRS_PLINK_0.000199526231496888 TRUE 536.7 Complications of gastrostomy, colostomy and enterostomy Both 1 30 10 digestive chartreuse4 30, 1 8, 0 7, 0 7, 1 8, 0 0.286 0.87 0.742 0.13 1.33 0.0606 22.3 0.781 1.98 0.693 0.159 2.18 0.0251 49900 PRS_PLINK_0.000199526231496888 TRUE 536.8 Dyspepsia and other specified disorders of function of stomach Both 38 218 10 digestive chartreuse4 218, 38 55, 10 54, 8 54, 8 55, 12 0.136 0.183 0.456 0.341 1.15 0.797 1.65 -0.19 0.545 0.727 0.138 0.827 0.274 2.4 -0.145 0.524 0.782 0.107 0.865 0.302 2.42 0.435 0.503 0.387 0.413 1.55 0.574 4.25 PRS_PLINK_0.000199526231496888 TRUE 537 Other disorders of stomach and duodenum Both 37 259 10 digestive chartreuse4 259, 37 64, 7 65, 10 64, 8 65, 12 0.149 0.176 0.4 0.398 1.16 0.819 1.66 0.207 0.546 0.705 0.152 1.23 0.41 3.77 0.157 0.542 0.772 0.112 1.17 0.393 3.52 0.544 0.497 0.274 0.563 1.72 0.651 4.82 PRS_PLINK_0.000199526231496888 TRUE 537.1 Lesions of stomach and duodenum Both 1 8 10 digestive chartreuse4 8, 1 2, 0 2, 0 2, 0 2, 1 -2.06 80 0.979 0.009 0.127 0.112 0.145 0.103 344 1 0 1.11 0.24 8.55 PRS_PLINK_0.000199526231496888 TRUE 539 Bariatric surgery Both 48 172 10 digestive chartreuse4 172, 48 42, 21 43, 8 43, 7 43, 12 -0.0553 0.168 0.742 0.13 0.946 0.682 1.31 -0.872 0.484 0.0716 1.145 0.418 0.157 1.03 -0.967 0.495 0.051 1.293 0.38 0.138 0.957 -0.289 0.454 0.524 0.281 0.749 0.309 1.78 PRS_PLINK_0.000199526231496888 TRUE 540 Appendiceal conditions Both 18 59 10 digestive chartreuse4 59, 18 15, 3 15, 5 14, 4 15, 6 0.197 0.293 0.501 0.3 1.22 0.705 2.17 0.684 0.872 0.433 0.363 1.98 0.418 11.5 -0.328 1 0.744 0.129 0.72 0.0757 5.88 0.558 0.852 0.513 0.29 1.75 0.372 10.6 PRS_PLINK_0.000199526231496888 TRUE 540.1 Appendicitis Both 16 59 10 digestive chartreuse4 59, 16 15, 2 15, 5 14, 3 15, 6 0.328 0.319 0.303 0.518 1.39 0.769 2.66 0.588 0.934 0.529 0.277 1.8 0.309 11.3 0.0595 1.06 0.955 0.02 1.06 0.105 10.6 1.18 0.978 0.229 0.64 3.24 0.565 26.6 PRS_PLINK_0.000199526231496888 TRUE 540.11 Acute appendicitis Both 16 46 10 digestive chartreuse4 46, 16 12, 2 11, 4 11, 4 12, 6 0.356 0.322 0.27 0.568 1.43 0.798 2.76 0.817 0.985 0.407 0.39 2.26 0.405 16.7 0.389 1.1 0.723 0.141 1.48 0.203 11.3 1.19 0.99 0.23 0.638 3.28 0.58 28.8 PRS_PLINK_0.000199526231496888 TRUE 550 Abdominal hernia Both 82 332 10 digestive chartreuse4 332, 82 82, 27 83, 23 83, 15 83, 17 -0.168 0.127 0.185 0.732 0.845 0.659 1.08 -0.135 0.341 0.693 0.159 0.874 0.448 1.7 -0.489 0.391 0.211 0.677 0.613 0.282 1.3 -0.39 0.36 0.279 0.554 0.677 0.332 1.35 PRS_PLINK_0.000199526231496888 FALSE 550.1 Inguinal hernia Both 9 63 10 digestive chartreuse4 63, 9 16, 4 16, 1 15, 4 16, 0 -0.244 0.384 0.525 0.28 0.783 0.317 1.68 -0.643 1.21 0.594 0.226 0.526 0.0321 4.8 -0.197 1.04 0.849 0.071 0.821 0.0871 6.15 -1.45 1.41 0.304 0.517 0.234 3.6e-08 2.77 PRS_PLINK_0.000199526231496888 TRUE 550.2 Diaphragmatic hernia Both 32 191 10 digestive chartreuse4 191, 32 47, 10 48, 7 47, 8 48, 7 0.00338 0.187 0.986 0.006 1 0.695 1.46 -0.339 0.533 0.525 0.28 0.712 0.242 2.01 -0.285 0.528 0.589 0.23 0.752 0.262 2.09 -0.32 0.536 0.551 0.259 0.726 0.246 2.06 PRS_PLINK_0.000199526231496888 TRUE 550.3 Femoral hernia Both 2 10 10 digestive chartreuse4 10, 2 3, 0 2, 0 2, 1 3, 1 0.0487 0.861 0.955 0.02 1.05 0.101 3.26 -2.31 19500000 1 0 0.0989 2.69e-11 5.73e+08 -0.0447 531 1 0 0.956 0.252 1.31 PRS_PLINK_0.000199526231496888 TRUE 550.4 Umbilical hernia Both 28 91 10 digestive chartreuse4 91, 28 23, 7 23, 7 22, 8 23, 6 -0.0548 0.222 0.805 0.094 0.947 0.611 1.45 0.145 0.657 0.825 0.083 1.16 0.334 4.01 -0.0309 0.701 0.965 0.016 0.97 0.245 3.75 -0.253 0.68 0.711 0.148 0.777 0.211 2.8 PRS_PLINK_0.000199526231496888 TRUE 550.5 Ventral hernia Both 29 155 10 digestive chartreuse4 155, 29 38, 7 39, 6 38, 9 39, 7 -0.0458 0.205 0.823 0.084 0.955 0.638 1.43 0.154 0.605 0.799 0.097 1.17 0.35 4.02 0.116 0.56 0.836 0.078 1.12 0.374 3.43 0.0118 0.64 0.985 0.006 1.01 0.283 3.64 PRS_PLINK_0.000199526231496888 TRUE 550.6 Incisional hernia Both 23 89 10 digestive chartreuse4 89, 23 23, 4 22, 5 22, 8 22, 6 0.144 0.245 0.557 0.254 1.15 0.723 1.87 0.448 0.723 0.535 0.271 1.57 0.393 6.86 0.298 0.715 0.677 0.169 1.35 0.344 5.64 0.332 0.729 0.649 0.188 1.39 0.35 6.22 PRS_PLINK_0.000199526231496888 TRUE 555 Inflammatory bowel disease and other gastroenteritis and colitis Both 17 118 10 digestive chartreuse4 118, 17 29, 5 29, 3 29, 3 30, 6 0.0871 0.333 0.794 0.1 1.09 0.555 2.23 -0.637 0.952 0.503 0.298 0.529 0.0442 4.1 -0.0491 1.02 0.962 0.017 0.952 0.0923 9.14 0.427 1 0.671 0.173 1.53 0.175 16.5 PRS_PLINK_0.000199526231496888 TRUE 555.1 Regional enteritis Both 14 70 10 digestive chartreuse4 70, 14 18, 5 17, 4 17, 1 18, 4 0.165 0.385 0.669 0.175 1.18 0.554 2.71 0.823 1.34 0.54 0.267 2.28 0.125 555 0.294 1.18 0.804 0.095 1.34 0.0948 24.6 0.65 1.15 0.573 0.242 1.92 0.204 23.3 PRS_PLINK_0.000199526231496888 TRUE 555.2 Ulcerative colitis Both 7 69 10 digestive chartreuse4 69, 7 18, 1 17, 1 17, 2 17, 3 1.02 0.691 0.142 0.848 2.76 0.732 23 -0.0915 1.3 0.944 0.025 0.913 0.00769 22.3 1.07 1.39 0.442 0.355 2.91 0.123 42500 2.08 1.6 0.194 0.712 8.02 0.494 11300 PRS_PLINK_0.000199526231496888 TRUE 555.21 Ulcerative colitis (chronic) Both 2 38 10 digestive chartreuse4 38, 2 10, 0 9, 0 9, 0 10, 2 0.517 0.739 0.484 0.315 1.68 0.285 58.8 0.706 1.62 0.664 0.178 2.03 0.0863 472 PRS_PLINK_0.000199526231496888 TRUE 556 Ulceration of the lower GI tract Both 9 27 10 digestive chartreuse4 27, 9 7, 1 7, 3 6, 2 7, 3 -0.199 0.524 0.704 0.153 0.819 0.293 2.16 -2.77 3.29 0.399 0.399 0.0624 1.47e-06 412 1.34 2.51 0.593 0.227 3.84 0.0335 2910000 -0.165 1.68 0.922 0.035 0.848 0.0357 20.4 PRS_PLINK_0.000199526231496888 TRUE 556.1 Ulceration of intestine Both 9 24 10 digestive chartreuse4 24, 9 6, 2 6, 4 6, 0 6, 3 -1.19 0.839 0.157 0.805 0.305 0.0361 1.47 -1.44 2.3 0.533 0.273 0.238 8.54e-05 64.7 -0.617 2.24 0.783 0.106 0.54 0.000577 64.9 -0.734 2.68 0.784 0.106 0.48 4.42e-05 78.8 PRS_PLINK_0.000199526231496888 TRUE 556.11 Angiodysplasia of intestine (without mention of hemorrhage) Both 2 5 10 digestive chartreuse4 5, 2 2, 0 1, 2 1, 0 1, 0 -0.0711 1980 1 0 0.931 0.572 1.34 -0.0584 14800 1 0 0.943 0.112 7.54 PRS_PLINK_0.000199526231496888 TRUE 557 Intestinal malabsorption (non-celiac) Both 55 157 10 digestive chartreuse4 157, 55 39, 18 39, 11 39, 13 39, 13 -0.0136 0.163 0.933 0.03 0.986 0.72 1.36 -0.24 0.459 0.601 0.221 0.786 0.321 1.89 -0.349 0.455 0.443 0.354 0.705 0.291 1.67 -0.113 0.474 0.811 0.091 0.893 0.36 2.21 PRS_PLINK_0.000199526231496888 FALSE 557.1 Celiac disease Both 10 44 10 digestive chartreuse4 44, 10 11, 2 11, 4 11, 4 11, 0 -1.18 0.609 0.052 1.284 0.306 0.0716 0.931 -0.0388 1.43 0.978 0.009 0.962 0.0252 99 0.714 1.4 0.61 0.215 2.04 0.134 786 -1.61 2.07 0.437 0.36 0.2 0.000206 14.9 PRS_PLINK_0.000199526231496888 TRUE 558 Noninfectious gastroenteritis Both 71 200 10 digestive chartreuse4 200, 71 49, 21 50, 21 50, 14 50, 15 -0.108 0.147 0.462 0.336 0.897 0.674 1.19 -0.041 0.39 0.916 0.038 0.96 0.454 2.02 -0.372 0.418 0.374 0.427 0.689 0.302 1.53 -0.471 0.429 0.273 0.564 0.624 0.27 1.4 PRS_PLINK_0.000199526231496888 FALSE 559 Ileostomy status Both 2 44 10 digestive chartreuse4 44, 2 11, 1 11, 1 11, 0 11, 0 0.0363 0.845 0.966 0.015 1.04 0.0219 205 -0.553 1.47 0.707 0.15 0.575 0.00419 31 0.0188 1.77 0.992 0.004 1.02 0.000145 406 0.0403 1.5 0.979 0.009 1.04 0.00722 113 PRS_PLINK_0.000199526231496888 TRUE 560 Intestinal obstruction without mention of hernia Both 32 157 10 digestive chartreuse4 157, 32 39, 6 39, 8 39, 13 39, 5 0.0133 0.209 0.949 0.023 1.01 0.674 1.53 0.387 0.653 0.553 0.258 1.47 0.411 5.64 0.813 0.631 0.197 0.704 2.26 0.689 8.19 -0.176 0.671 0.793 0.101 0.839 0.212 3.19 PRS_PLINK_0.000199526231496888 TRUE 560.1 Paralytic ileus Both 15 76 10 digestive chartreuse4 76, 15 19, 3 19, 6 19, 3 19, 3 -0.0524 0.307 0.864 0.063 0.949 0.519 1.73 1.42 1.14 0.213 0.671 4.13 0.521 84 0.102 1.02 0.92 0.036 1.11 0.143 10.5 0.16 0.902 0.859 0.066 1.17 0.199 7.15 PRS_PLINK_0.000199526231496888 TRUE 560.2 Impaction of intestine Both 9 34 10 digestive chartreuse4 34, 9 8, 4 8, 0 8, 5 9, 0 -0.246 0.423 0.561 0.251 0.782 0.332 1.79 -0.0554 1.9 0.977 0.01 0.946 0.00557 90.2 0.799 1.21 0.51 0.292 2.22 0.293 40.2 -0.984 1.58 0.534 0.273 0.374 0.000116 6.53 PRS_PLINK_0.000199526231496888 TRUE 560.3 Peritoneal or intestinal adhesions Both 2 15 10 digestive chartreuse4 15, 2 4, 1 4, 0 3, 1 4, 0 0.156 0.88 0.86 0.066 1.17 0.0203 102 -4.18e-15 2.89 1 0 1 0.0198 207 -2.51 7.86 0.749 0.125 0.0811 2.67e-06 995 -0.271 408 0.999 0 0.762 0.0327 23.9 PRS_PLINK_0.000199526231496888 TRUE 560.4 Other intestinal obstruction Both 18 93 10 digestive chartreuse4 93, 18 23, 3 23, 8 23, 5 23, 2 -0.00953 0.259 0.971 0.013 0.991 0.599 1.66 0.567 0.76 0.455 0.342 1.76 0.402 8.37 0.736 0.97 0.448 0.349 2.09 0.304 17 -1.13 1.01 0.262 0.582 0.323 0.0225 2.57 PRS_PLINK_0.000199526231496888 TRUE 561 Symptoms involving digestive system Both 42 170 10 digestive chartreuse4 170, 42 42, 9 42, 13 42, 7 43, 13 0.154 0.196 0.431 0.365 1.17 0.798 1.73 0.398 0.535 0.458 0.34 1.49 0.538 4.37 0.0388 0.629 0.951 0.022 1.04 0.297 3.63 0.565 0.559 0.312 0.506 1.76 0.609 5.56 PRS_PLINK_0.000199526231496888 TRUE 562 Diverticulosis and diverticulitis Both 70 116 10 digestive chartreuse4 116, 70 28, 15 29, 17 29, 21 29, 17 0.156 0.177 0.378 0.423 1.17 0.832 1.65 -0.0524 0.518 0.919 0.036 0.949 0.351 2.53 0.103 0.542 0.849 0.071 1.11 0.396 3.13 0.00427 0.512 0.993 0.003 1 0.377 2.67 PRS_PLINK_0.000199526231496888 FALSE 562.1 Diverticulosis Both 70 116 10 digestive chartreuse4 116, 70 28, 15 29, 17 29, 21 29, 17 0.156 0.177 0.378 0.423 1.17 0.832 1.65 -0.0524 0.518 0.919 0.036 0.949 0.351 2.53 0.103 0.542 0.849 0.071 1.11 0.396 3.13 0.00427 0.512 0.993 0.003 1 0.377 2.67 PRS_PLINK_0.000199526231496888 FALSE 562.2 Diverticulitis Both 16 48 10 digestive chartreuse4 48, 16 12, 0 12, 6 12, 7 12, 3 0.335 0.294 0.255 0.594 1.4 0.821 2.48 3.26 1.79 0.0687 1.163 26.2 1.35 24500 2.67 1.61 0.0981 1.008 14.4 0.999 2660 0.303 1.41 0.829 0.081 1.35 0.0918 139 PRS_PLINK_0.000199526231496888 TRUE 564 Functional digestive disorders Both 159 205 10 digestive chartreuse4 205, 159 51, 40 51, 40 51, 35 51, 44 0.0799 0.113 0.48 0.319 1.08 0.871 1.35 0.0212 0.327 0.948 0.023 1.02 0.544 1.91 -0.236 0.337 0.484 0.315 0.79 0.412 1.5 0.00141 0.325 0.997 0.002 1 0.537 1.87 PRS_PLINK_0.000199526231496888 FALSE 564.1 Irritable Bowel Syndrome Both 77 191 10 digestive chartreuse4 191, 77 47, 18 48, 21 47, 20 48, 18 0.0947 0.144 0.512 0.291 1.1 0.834 1.46 0.23 0.433 0.595 0.225 1.26 0.548 2.94 0.137 0.423 0.746 0.127 1.15 0.51 2.62 -0.122 0.447 0.786 0.105 0.886 0.374 2.08 PRS_PLINK_0.000199526231496888 FALSE 564.9 Personal history of diseases of digestive system Both 39 185 10 digestive chartreuse4 185, 39 46, 12 46, 6 46, 8 46, 13 0.158 0.187 0.397 0.401 1.17 0.812 1.71 -0.666 0.556 0.231 0.637 0.514 0.161 1.48 -0.833 0.549 0.129 0.888 0.435 0.141 1.25 -0.0802 0.507 0.874 0.058 0.923 0.34 2.48 PRS_PLINK_0.000199526231496888 TRUE 565 Anal and rectal conditions Both 46 246 10 digestive chartreuse4 246, 46 61, 12 61, 12 61, 13 62, 9 -0.0715 0.166 0.667 0.176 0.931 0.674 1.29 0.315 0.477 0.509 0.293 1.37 0.544 3.55 -0.0391 0.478 0.935 0.029 0.962 0.377 2.45 -0.0764 0.517 0.883 0.054 0.926 0.336 2.54 PRS_PLINK_0.000199526231496888 TRUE 565.1 Anal and rectal polyp Both 18 62 10 digestive chartreuse4 62, 18 16, 6 15, 3 15, 7 16, 2 -0.22 0.292 0.453 0.344 0.803 0.45 1.38 -1.34 1.09 0.22 0.658 0.261 0.0172 2.02 0.181 0.743 0.808 0.093 1.2 0.303 4.73 -1.27 0.986 0.197 0.706 0.28 0.0262 1.59 PRS_PLINK_0.000199526231496888 TRUE 567 Peritonitis and retroperitoneal infections Both 11 102 10 digestive chartreuse4 102, 11 26, 4 25, 1 25, 3 26, 3 0.109 0.324 0.736 0.133 1.12 0.576 2.14 -0.681 0.952 0.475 0.324 0.506 0.0484 3.46 -0.318 0.839 0.705 0.152 0.728 0.115 3.86 -0.273 0.824 0.74 0.131 0.761 0.137 3.83 PRS_PLINK_0.000199526231496888 TRUE 568 Other disorders of peritoneum Both 14 112 10 digestive chartreuse4 112, 14 28, 6 28, 3 28, 2 28, 3 -0.0755 0.264 0.775 0.111 0.927 0.542 1.58 -0.974 0.85 0.252 0.599 0.378 0.0519 1.96 -0.582 0.759 0.443 0.354 0.559 0.103 2.51 -0.57 0.737 0.439 0.358 0.565 0.117 2.28 PRS_PLINK_0.000199526231496888 TRUE 568.1 Peritoneal adhesions (postoperative) (postinfection) Both 12 89 10 digestive chartreuse4 89, 12 23, 5 22, 2 22, 2 22, 3 -0.0775 0.285 0.786 0.105 0.925 0.513 1.64 -1.59 1.11 0.154 0.812 0.205 0.0101 1.59 -0.916 0.913 0.316 0.501 0.4 0.0517 2.24 -0.383 0.809 0.636 0.196 0.682 0.125 3.22 PRS_PLINK_0.000199526231496888 TRUE 569 Other disorders of intestine Both 91 319 10 digestive chartreuse4 319, 91 79, 25 80, 23 79, 21 80, 22 -0.0237 0.127 0.852 0.069 0.977 0.762 1.25 -0.0184 0.367 0.96 0.018 0.982 0.481 2 -0.162 0.371 0.663 0.178 0.851 0.411 1.75 -0.231 0.364 0.525 0.279 0.794 0.39 1.6 PRS_PLINK_0.000199526231496888 FALSE 569.1 Toxic gastroenteritis and colitis Both 3 34 10 digestive chartreuse4 34, 3 9, 1 8, 1 8, 1 9, 0 -0.755 0.737 0.306 0.514 0.47 0.0479 1.83 0.195 1.56 0.901 0.045 1.21 0.00461 159 0.157 1.89 0.934 0.03 1.17 0.00479 224 -0.47 1.73 0.786 0.104 0.625 3.21e-05 82.6 PRS_PLINK_0.000199526231496888 TRUE 569.2 Gastrointestinal complications Both 17 115 10 digestive chartreuse4 115, 17 29, 5 29, 5 28, 3 29, 4 0.0311 0.255 0.903 0.044 1.03 0.628 1.71 -0.539 0.76 0.478 0.32 0.583 0.121 2.54 -0.494 0.801 0.538 0.269 0.61 0.112 2.95 -0.318 0.765 0.678 0.169 0.728 0.152 3.32 PRS_PLINK_0.000199526231496888 TRUE 571 Chronic liver disease and cirrhosis Both 60 240 10 digestive chartreuse4 240, 60 59, 14 60, 18 60, 13 60, 15 0.0748 0.154 0.628 0.202 1.08 0.799 1.46 0.275 0.405 0.497 0.304 1.32 0.602 2.93 -0.0827 0.45 0.854 0.068 0.921 0.381 2.21 0.254 0.447 0.569 0.245 1.29 0.542 3.12 PRS_PLINK_0.000199526231496888 FALSE 571.5 Other chronic nonalcoholic liver disease Both 57 235 10 digestive chartreuse4 235, 57 58, 13 59, 17 58, 12 59, 15 0.0831 0.157 0.596 0.224 1.09 0.801 1.48 0.292 0.418 0.484 0.315 1.34 0.597 3.07 -0.0547 0.458 0.905 0.043 0.947 0.387 2.32 0.3 0.452 0.507 0.295 1.35 0.563 3.3 PRS_PLINK_0.000199526231496888 FALSE 571.51 Cirrhosis of liver without mention of alcohol Both 4 49 10 digestive chartreuse4 49, 4 13, 1 12, 2 12, 1 12, 0 -0.0562 0.582 0.923 0.035 0.945 0.269 4.04 0.0898 1.23 0.942 0.026 1.09 0.0946 18.3 -0.294 1.4 0.834 0.079 0.745 0.0124 31.2 -0.415 1.42 0.771 0.113 0.66 0.000391 16.5 PRS_PLINK_0.000199526231496888 TRUE 571.6 Primary biliary cirrhosis Both 1 18 10 digestive chartreuse4 18, 1 5, 0 4, 1 4, 0 5, 0 -0.0825 1.28 0.949 0.023 0.921 0.00485 40.3 -0.214 2.8 0.939 0.027 0.807 0.00304 453 PRS_PLINK_0.000199526231496888 TRUE 571.8 Liver abscess and sequelae of chronic liver disease Both 6 55 10 digestive chartreuse4 55, 6 14, 2 14, 1 13, 3 14, 0 -0.204 0.498 0.682 0.166 0.816 0.255 2.47 -0.813 1.37 0.554 0.256 0.444 0.01 8.72 -0.205 1.06 0.847 0.072 0.814 0.0844 6.49 -0.152 1.24 0.903 0.044 0.859 0.0413 34.2 PRS_PLINK_0.000199526231496888 TRUE 571.81 Portal hypertension Both 3 33 10 digestive chartreuse4 33, 3 9, 1 8, 2 8, 0 8, 0 -0.198 0.666 0.766 0.116 0.82 0.213 4.26 1.22 1.71 0.474 0.325 3.39 0.194 1200000 -0.155 1.6 0.923 0.035 0.856 6.6e-05 2260 -1.03 2.17 0.633 0.198 0.356 0.00208 81.7 PRS_PLINK_0.000199526231496888 TRUE 572 Ascites (non malignant) Both 34 158 10 digestive chartreuse4 158, 34 39, 10 39, 7 39, 7 40, 10 0.174 0.215 0.419 0.378 1.19 0.787 1.84 -0.298 0.61 0.625 0.204 0.742 0.216 2.4 -0.389 0.599 0.516 0.287 0.678 0.203 2.14 0.475 0.577 0.41 0.387 1.61 0.532 5.12 PRS_PLINK_0.000199526231496888 TRUE 573 Other disorders of liver Both 70 277 10 digestive chartreuse4 277, 70 69, 17 69, 22 69, 16 69, 15 -0.0363 0.144 0.801 0.096 0.964 0.728 1.28 0.229 0.375 0.542 0.266 1.26 0.61 2.63 -0.138 0.411 0.737 0.133 0.871 0.389 1.93 0.0726 0.426 0.864 0.063 1.08 0.467 2.47 PRS_PLINK_0.000199526231496888 FALSE 573.1 Chronic passive congestion of liver Both 2 8 10 digestive chartreuse4 8, 2 2, 0 2, 1 2, 1 2, 0 -9.4e-14 4.45 1 0 1 0.0176 72.7 0.48 1020 1 0 1.62 0.0136 2400 0.000497 66.8 1 0 1 0.629 1.49 PRS_PLINK_0.000199526231496888 TRUE 573.2 Liver replaced by transplant Both 8 22 10 digestive chartreuse4 22, 8 6, 6 5, 0 5, 1 6, 1 -0.467 0.567 0.411 0.387 0.627 0.214 1.66 -1.82 1.7 0.284 0.546 0.162 0.000715 2.08 -1.72 1.61 0.286 0.544 0.18 0.000186 2.04 -1.22 1.58 0.437 0.359 0.294 0.243 2.7 PRS_PLINK_0.000199526231496888 TRUE 573.3 Hepatomegaly Both 5 44 10 digestive chartreuse4 44, 5 11, 1 11, 2 11, 2 11, 0 -0.123 0.556 0.825 0.084 0.884 0.207 2.97 1.4 1.52 0.358 0.446 4.05 0.315 3410 0.615 1.28 0.63 0.2 1.85 0.125 25800 -0.903 1.57 0.565 0.248 0.405 0.00385 21.5 PRS_PLINK_0.000199526231496888 TRUE 573.4 Acute and subacute necrosis of liver Both 4 15 10 digestive chartreuse4 15, 4 4, 1 4, 0 3, 3 4, 0 -0.266 0.683 0.697 0.157 0.766 0.056 2.35 1.03e-11 69 1 0 1 2.25e-18 1.68e+18 -0.917 2.25 0.684 0.165 0.4 0.367 0.452 4.88e-13 4.56 1 0 1 0.000776 1010 PRS_PLINK_0.000199526231496888 TRUE 573.5 Jaundice (not of newborn) Both 8 61 10 digestive chartreuse4 61, 8 16, 4 15, 0 15, 2 15, 2 -0.209 0.432 0.628 0.202 0.811 0.329 1.92 -1.63 1.29 0.207 0.684 0.195 3.77e-05 1.76 -0.971 1.06 0.361 0.442 0.379 0.0189 2.57 -0.132 0.974 0.893 0.049 0.877 0.116 5.93 PRS_PLINK_0.000199526231496888 TRUE 573.6 Nonspecific elevation of levels of transaminase or lactic acid dehydrogenase [LDH] Both 55 163 10 digestive chartreuse4 163, 55 41, 15 41, 14 40, 9 41, 17 0.0355 0.168 0.832 0.08 1.04 0.749 1.44 -0.0496 0.463 0.915 0.039 0.952 0.388 2.32 -0.619 0.503 0.219 0.66 0.539 0.199 1.39 0.186 0.459 0.686 0.164 1.2 0.497 2.91 PRS_PLINK_0.000199526231496888 FALSE 573.7 Abnormal results of function study of liver Both 52 181 10 digestive chartreuse4 181, 52 46, 12 45, 19 45, 10 45, 11 0.0484 0.174 0.781 0.107 1.05 0.748 1.47 0.447 0.446 0.316 0.5 1.56 0.669 3.78 -0.18 0.487 0.711 0.148 0.835 0.32 2.14 0.465 0.509 0.362 0.442 1.59 0.599 4.39 PRS_PLINK_0.000199526231496888 FALSE 573.9 Abnormal serum enzyme levels Both 85 267 10 digestive chartreuse4 267, 85 66, 22 67, 21 66, 18 67, 24 0.0864 0.132 0.514 0.289 1.09 0.843 1.41 0.0177 0.369 0.962 0.017 1.02 0.496 2.09 -0.184 0.374 0.622 0.206 0.832 0.401 1.71 0.265 0.375 0.48 0.319 1.3 0.632 2.71 PRS_PLINK_0.000199526231496888 FALSE 574 Cholelithiasis and cholecystitis Both 78 292 10 digestive chartreuse4 292, 78 72, 17 73, 22 73, 16 73, 23 0.0949 0.131 0.467 0.331 1.1 0.854 1.42 0.0619 0.379 0.87 0.06 1.06 0.507 2.24 -0.0617 0.393 0.875 0.058 0.94 0.432 2.04 0.0362 0.387 0.926 0.034 1.04 0.487 2.21 PRS_PLINK_0.000199526231496888 FALSE 574.1 Cholelithiasis Both 78 277 10 digestive chartreuse4 277, 78 69, 17 69, 22 69, 15 69, 24 0.109 0.133 0.413 0.384 1.12 0.863 1.45 0.0726 0.38 0.848 0.071 1.08 0.513 2.27 -0.135 0.397 0.734 0.134 0.874 0.398 1.91 0.0856 0.387 0.825 0.084 1.09 0.514 2.32 PRS_PLINK_0.000199526231496888 FALSE 574.11 Cholelithiasis with acute cholecystitis Both 9 25 10 digestive chartreuse4 25, 9 7, 3 6, 3 6, 1 6, 2 -0.592 0.705 0.401 0.397 0.553 0.127 1.91 -0.319 1.25 0.798 0.098 0.727 0.0701 5.8 -1.05 1.86 0.574 0.241 0.352 8.55e-05 5.41 -0.951 2.07 0.646 0.19 0.386 0.000415 16.2 PRS_PLINK_0.000199526231496888 TRUE 574.12 Cholelithiasis with other cholecystitis Both 19 55 10 digestive chartreuse4 55, 19 14, 7 14, 4 13, 2 14, 6 -0.21 0.339 0.535 0.272 0.81 0.411 1.6 -1.85 1.1 0.0931 1.031 0.157 0.0098 1.09 -1.22 1.04 0.238 0.623 0.294 0.023 2.02 -0.622 0.818 0.447 0.35 0.537 0.104 2.43 PRS_PLINK_0.000199526231496888 TRUE 574.2 Calculus of bile duct Both 23 91 10 digestive chartreuse4 91, 23 23, 4 23, 7 22, 1 23, 11 0.26 0.267 0.33 0.482 1.3 0.779 2.22 0.189 0.772 0.806 0.094 1.21 0.257 5.68 0.0176 1.17 0.988 0.005 1.02 0.061 1.29 0.642 0.703 0.361 0.442 1.9 0.508 7.83 PRS_PLINK_0.000199526231496888 TRUE 574.3 Cholecystitis without cholelithiasis Both 12 72 10 digestive chartreuse4 72, 12 18, 4 18, 3 18, 2 18, 3 0.0829 0.326 0.799 0.098 1.09 0.585 2.04 -1.1 0.974 0.26 0.586 0.334 0.0372 1.96 -0.733 0.896 0.413 0.384 0.481 0.0693 2.56 -0.441 0.849 0.604 0.219 0.644 0.119 3.08 PRS_PLINK_0.000199526231496888 TRUE 575 Other biliary tract disease Both 49 189 10 digestive chartreuse4 189, 49 47, 14 47, 10 47, 15 47, 10 -0.0471 0.175 0.788 0.104 0.954 0.678 1.34 -0.403 0.473 0.394 0.405 0.668 0.263 1.65 -0.0184 0.436 0.966 0.015 0.982 0.421 2.29 -0.392 0.469 0.403 0.395 0.676 0.266 1.66 PRS_PLINK_0.000199526231496888 TRUE 575.1 Cholangitis Both 2 18 10 digestive chartreuse4 18, 2 5, 0 4, 0 4, 0 5, 2 0.674 0.826 0.415 0.382 1.96 0.47 1630 1.68 2.08 0.419 0.378 5.36 0.258 2260 PRS_PLINK_0.000199526231496888 TRUE 575.2 Obstruction of bile duct Both 6 36 10 digestive chartreuse4 36, 6 9, 2 9, 3 9, 0 9, 1 -0.228 0.645 0.724 0.14 0.796 0.186 2.8 -0.422 1.18 0.72 0.143 0.656 0.0604 4.99 -0.782 1.69 0.643 0.192 0.458 0.0011 10.7 -0.804 1.5 0.592 0.227 0.448 0.00735 9.54 PRS_PLINK_0.000199526231496888 TRUE 575.6 Cholesterolosis of gallbladder Both 9 21 10 digestive chartreuse4 21, 9 5, 4 5, 2 5, 2 5, 1 -0.256 0.527 0.627 0.203 0.774 0.251 1.98 -1.48 1.72 0.388 0.411 0.227 0.00727 3.23 -0.653 1.79 0.715 0.146 0.521 0.00282 10.7 -1.75 2.83 0.537 0.27 0.174 0.000142 13.4 PRS_PLINK_0.000199526231496888 TRUE 575.7 Other disorders of gallbladder Both 26 79 10 digestive chartreuse4 79, 26 20, 8 20, 8 19, 5 20, 5 -0.11 0.262 0.675 0.171 0.896 0.537 1.47 -0.0937 0.721 0.897 0.047 0.911 0.233 3.55 -0.639 0.728 0.38 0.42 0.528 0.114 2.09 -0.59 0.717 0.411 0.387 0.554 0.135 2.04 PRS_PLINK_0.000199526231496888 TRUE 575.8 Other disorders of biliary tract Both 20 91 10 digestive chartreuse4 91, 20 23, 6 23, 6 22, 3 23, 5 0.0461 0.321 0.886 0.053 1.05 0.553 2.01 -0.0597 0.688 0.931 0.031 0.942 0.242 3.64 -0.788 0.817 0.335 0.475 0.455 0.0802 2.2 0.0208 0.796 0.979 0.009 1.02 0.208 5.4 PRS_PLINK_0.000199526231496888 TRUE 575.9 Nonspecific abnormal findings on radiological and other examination of biliary tract Both 4 11 10 digestive chartreuse4 11, 4 3, 0 3, 2 2, 1 3, 1 1.08 1.16 0.353 0.453 2.93 0.529 46.1 -0.878 290 0.998 0.001 0.416 0.197 2.16 0.387 426 0.999 0 1.47 1.42 4.68 -0.212 542 1 0 0.809 0.0908 2.71 PRS_PLINK_0.000199526231496888 TRUE 577 Diseases of pancreas Both 27 178 10 digestive chartreuse4 178, 27 45, 8 44, 5 44, 3 45, 11 0.101 0.198 0.608 0.216 1.11 0.749 1.64 -0.263 0.604 0.663 0.178 0.769 0.219 2.53 -0.64 0.643 0.32 0.495 0.527 0.126 1.83 0.332 0.52 0.523 0.282 1.39 0.516 3.91 PRS_PLINK_0.000199526231496888 TRUE 577.1 Acute pancreatitis Both 13 108 10 digestive chartreuse4 108, 13 27, 5 27, 2 27, 1 27, 5 0.0295 0.309 0.924 0.034 1.03 0.548 1.97 -0.656 0.853 0.441 0.355 0.519 0.0765 2.65 -0.924 0.869 0.288 0.541 0.397 0.0379 2 -0.435 0.737 0.555 0.256 0.647 0.138 2.68 PRS_PLINK_0.000199526231496888 TRUE 577.2 Chronic pancreatitis Both 5 46 10 digestive chartreuse4 46, 5 12, 2 11, 1 11, 1 12, 1 -0.277 0.502 0.582 0.235 0.758 0.215 1.96 0.66 1.42 0.641 0.193 1.94 0.16 53.7 -0.0748 1.21 0.951 0.022 0.928 0.0773 12.6 -0.577 1.14 0.613 0.212 0.562 0.0385 4.81 PRS_PLINK_0.000199526231496888 TRUE 577.3 Cyst and pseudocyst of pancreas Both 6 44 10 digestive chartreuse4 44, 6 11, 4 11, 1 11, 0 11, 1 -0.937 0.664 0.158 0.801 0.392 0.0411 1.32 -0.577 1.54 0.707 0.15 0.561 0.0131 23.3 -4.21 2.8 0.133 0.878 0.0149 6.46e-09 3.97 -2.04 1.49 0.171 0.766 0.13 0.000924 1.56 PRS_PLINK_0.000199526231496888 TRUE 578 Gastrointestinal hemorrhage Both 76 318 10 digestive chartreuse4 318, 76 79, 13 79, 24 79, 21 80, 18 0.11 0.134 0.411 0.386 1.12 0.86 1.46 0.512 0.383 0.181 0.741 1.67 0.796 3.6 0.448 0.409 0.274 0.562 1.56 0.71 3.57 0.0333 0.411 0.935 0.029 1.03 0.462 2.33 PRS_PLINK_0.000199526231496888 FALSE 578.1 Hematemesis Both 11 34 10 digestive chartreuse4 34, 11 9, 1 8, 3 8, 5 9, 2 0.679 0.563 0.228 0.642 1.97 0.727 7.73 0.291 1.16 0.801 0.096 1.34 0.153 14 2.18 1.42 0.124 0.906 8.81 0.909 253 0.167 1.36 0.902 0.045 1.18 0.0338 76.1 PRS_PLINK_0.000199526231496888 TRUE 578.2 Blood in stool Both 35 194 10 digestive chartreuse4 194, 35 48, 4 48, 9 48, 12 49, 10 0.201 0.194 0.3 0.523 1.22 0.838 1.8 0.334 0.703 0.635 0.197 1.4 0.326 6.71 0.939 0.649 0.148 0.83 2.56 0.74 10.8 0.753 0.641 0.24 0.621 2.12 0.618 8.26 PRS_PLINK_0.000199526231496888 TRUE 578.8 Hemorrhage of rectum and anus Both 41 188 10 digestive chartreuse4 188, 41 46, 11 47, 14 47, 8 47, 8 -0.0243 0.184 0.895 0.048 0.976 0.681 1.41 0.14 0.46 0.76 0.119 1.15 0.476 2.84 -0.42 0.53 0.428 0.368 0.657 0.223 1.87 -0.337 0.52 0.517 0.286 0.714 0.248 1.98 PRS_PLINK_0.000199526231496888 TRUE 578.9 Hemorrhage of gastrointestinal tract Both 22 86 10 digestive chartreuse4 86, 22 21, 5 21, 2 21, 8 22, 7 0.17 0.238 0.475 0.324 1.19 0.753 1.9 -1.97 1.25 0.114 0.943 0.139 0.00447 1.2 0.0217 0.672 0.974 0.011 1.02 0.288 3.69 -0.00405 0.714 0.995 0.002 0.996 0.249 3.98 PRS_PLINK_0.000199526231496888 TRUE 579 Other symptoms involving abdomen and pelvis Both 62 304 10 digestive chartreuse4 304, 62 75, 19 76, 15 76, 12 76, 16 -0.0698 0.141 0.621 0.207 0.933 0.707 1.23 -0.326 0.392 0.406 0.392 0.722 0.33 1.54 -0.52 0.433 0.229 0.639 0.594 0.245 1.38 -0.197 0.407 0.628 0.202 0.821 0.367 1.81 PRS_PLINK_0.000199526231496888 FALSE 579.2 Splenomegaly Both 10 57 10 digestive chartreuse4 57, 10 15, 3 14, 1 14, 4 14, 2 0.22 0.376 0.559 0.253 1.25 0.605 2.82 -1.43 1.39 0.302 0.52 0.239 0.000769 2.89 -0.16 0.913 0.861 0.065 0.853 0.15 4.89 0.519 1.12 0.643 0.192 1.68 0.195 19 PRS_PLINK_0.000199526231496888 TRUE 579.8 Nonspecific abnormal findings in stool contents Both 21 107 10 digestive chartreuse4 107, 21 26, 10 27, 1 26, 6 27, 4 -0.209 0.24 0.385 0.415 0.811 0.507 1.3 -1.98 0.911 0.0301 1.522 0.139 0.014 0.703 -0.734 0.628 0.243 0.615 0.48 0.136 1.53 -1.16 0.755 0.126 0.901 0.315 0.0604 1.26 PRS_PLINK_0.000199526231496888 TRUE 580 Nephritis; nephrosis; renal sclerosis Both 40 113 11 genitourinary black 113, 40 29, 17 28, 11 28, 7 28, 5 -0.328 0.216 0.128 0.893 0.72 0.469 1.08 -0.242 0.575 0.674 0.171 0.785 0.252 2.37 -0.821 0.585 0.16 0.795 0.44 0.138 1.3 -1.13 0.659 0.0875 1.058 0.324 0.0806 1.09 PRS_PLINK_0.000199526231496888 TRUE 580.1 Glomerulonephritis Both 20 25 11 genitourinary black 25, 20 7, 6 6, 7 6, 4 6, 3 0.526 0.505 0.297 0.527 1.69 0.658 4.93 0.0985 1.21 0.935 0.029 1.1 0.132 11.5 1.22 1.38 0.379 0.421 3.37 0.353 90.4 2.04 2.1 0.331 0.48 7.68 0.125 543000 PRS_PLINK_0.000199526231496888 TRUE 580.11 Proliferative glomerulonephritis Both 11 14 11 genitourinary black 14, 11 4, 5 3, 4 3, 1 4, 1 0.408 0.891 0.647 0.189 1.5 0.318 14.8 1.25 1.88 0.505 0.296 3.49 0.176 108 3.31 4.27 0.438 0.359 27.4 0.0288 2250000 1.43 3.93 0.717 0.145 4.17 0.000612 69600 PRS_PLINK_0.000199526231496888 TRUE 580.12 Non-proliferative glomerulonephritis Both 6 5 11 genitourinary black 5, 6 2, 1 1, 2 1, 1 1, 2 0.217 1.95 0.911 0.04 1.24 0.155 326 -0.44 1750 1 0 0.644 0.41 1.81 -0.023 1640 1 0 0.977 0.575 1.2 -0.184 14400 1 0 0.832 0.327 1.85 PRS_PLINK_0.000199526231496888 TRUE 580.13 Acute glomerulonephritis, NOS Both 1 5 11 genitourinary black 5, 1 2, 0 1, 0 1, 1 1, 0 -0.134 818 1 0 0.874 0.487 1.68 -0.454 36700 1 0 0.635 8.71e-05 7.45 PRS_PLINK_0.000199526231496888 TRUE 580.14 Chronic glomerulonephritis, NOS Both 16 14 11 genitourinary black 14, 16 4, 5 3, 2 3, 4 4, 5 0.947 0.658 0.15 0.824 2.58 0.837 12.5 -0.418 2.59 0.872 0.059 0.659 2.45e-09 889 0.178 1.73 0.918 0.037 1.19 0.0653 97.7 2.03 1.73 0.24 0.62 7.62 0.587 1800 PRS_PLINK_0.000199526231496888 TRUE 580.2 Nephrotic syndrome without mention of glomerulonephritis Both 14 16 11 genitourinary black 16, 14 4, 7 4, 4 4, 1 4, 2 -0.459 0.675 0.497 0.304 0.632 0.145 2.18 -0.516 1.41 0.714 0.146 0.597 0.0198 10.4 -0.91 1.41 0.519 0.285 0.402 0.0382 3.61 -0.371 1.77 0.834 0.079 0.69 0.0334 336 PRS_PLINK_0.000199526231496888 TRUE 580.3 Nephritis and nephropathy without mention of glomerulonephritis Both 29 91 11 genitourinary black 91, 29 23, 14 23, 8 22, 4 23, 3 -0.573 0.265 0.0304 1.517 0.564 0.329 0.919 -0.176 0.668 0.793 0.101 0.839 0.225 3 -1.19 0.712 0.0936 1.029 0.303 0.0663 1.1 -2.3 0.907 0.0111 1.955 0.0999 0.011 0.493 PRS_PLINK_0.000199526231496888 TRUE 580.31 Nephritis and nephropathy in diseases classified elsewhere Both 7 46 11 genitourinary black 46, 7 12, 4 11, 1 11, 0 12, 2 -0.331 0.417 0.427 0.369 0.718 0.304 1.6 -0.775 1.13 0.494 0.307 0.461 0.0297 3.78 -4.55 2.51 0.0699 1.156 0.0106 1.11e-06 0.551 -2.19 1.55 0.156 0.808 0.111 6.36e-05 1.83 PRS_PLINK_0.000199526231496888 TRUE 580.32 Nephritis and nephropathy with pathological lesion Both 27 60 11 genitourinary black 60, 27 15, 13 15, 7 15, 2 15, 5 -0.422 0.295 0.153 0.816 0.656 0.359 1.12 -0.925 0.941 0.326 0.487 0.397 0.0447 2.22 -1.38 0.963 0.153 0.815 0.253 0.0327 1.44 -0.757 0.77 0.326 0.487 0.469 0.0992 1.91 PRS_PLINK_0.000199526231496888 TRUE 580.4 Renal sclerosis, NOS Both 8 25 11 genitourinary black 25, 8 7, 4 6, 1 6, 2 6, 1 -0.379 0.501 0.449 0.348 0.684 0.623 1.68 -0.231 1.38 0.868 0.062 0.794 0.00612 1960 -0.86 1.57 0.584 0.234 0.423 0.0205 5.72 -0.958 1.81 0.597 0.224 0.384 1.07e-05 8.94 PRS_PLINK_0.000199526231496888 TRUE 585 Renal failure Both 84 253 11 genitourinary black 253, 84 63, 26 63, 26 63, 22 63, 10 -0.229 0.136 0.0938 1.028 0.796 0.609 1.03 0.261 0.361 0.471 0.327 1.3 0.648 2.64 0.0572 0.363 0.875 0.058 1.06 0.528 2.14 -0.851 0.452 0.0594 1.226 0.427 0.171 0.996 PRS_PLINK_0.000199526231496888 FALSE 585.1 Acute renal failure Both 50 152 11 genitourinary black 152, 50 38, 15 38, 11 38, 17 38, 7 -0.104 0.181 0.566 0.248 0.901 0.634 1.28 -0.178 0.498 0.721 0.142 0.837 0.317 2.17 0.37 0.47 0.431 0.366 1.45 0.597 3.62 -0.612 0.568 0.281 0.551 0.543 0.17 1.58 PRS_PLINK_0.000199526231496888 TRUE 585.2 Renal failure NOS Both 16 44 11 genitourinary black 44, 16 11, 3 11, 6 11, 4 11, 3 0.479 0.393 0.223 0.651 1.61 0.821 4.18 0.865 1.4 0.536 0.271 2.38 0.0601 68.5 2.87 1.98 0.147 0.833 17.6 0.387 38400000 2.42 1.85 0.192 0.716 11.2 0.393 23100 PRS_PLINK_0.000199526231496888 TRUE 585.3 Chronic renal failure [CKD] Both 65 196 11 genitourinary black 196, 65 49, 23 49, 19 49, 16 49, 7 -0.287 0.155 0.0649 1.188 0.751 0.553 1.01 0.108 0.399 0.786 0.105 1.11 0.518 2.42 -0.105 0.415 0.8 0.097 0.9 0.405 2 -1.03 0.505 0.0413 1.384 0.357 0.127 0.907 PRS_PLINK_0.000199526231496888 FALSE 585.31 Renal dialysis Both 21 39 11 genitourinary black 39, 21 10, 11 10, 6 9, 3 10, 1 -0.231 0.329 0.483 0.316 0.794 0.417 1.48 -0.339 0.844 0.688 0.163 0.712 0.147 3.38 1.19 1.53 0.439 0.358 3.28 0.182 5810 -0.504 1.33 0.706 0.151 0.604 0.0361 8.07 PRS_PLINK_0.000199526231496888 TRUE 585.32 End stage renal disease Both 37 50 11 genitourinary black 50, 37 13, 14 12, 12 12, 6 13, 5 -0.0804 0.249 0.747 0.127 0.923 0.571 1.48 0.471 0.782 0.547 0.262 1.6 0.365 7.88 -0.509 0.751 0.498 0.303 0.601 0.147 2.37 -0.493 0.847 0.56 0.251 0.611 0.124 2.81 PRS_PLINK_0.000199526231496888 TRUE 585.33 Chronic Kidney Disease, Stage III Both 32 97 11 genitourinary black 97, 32 25, 14 24, 9 24, 6 24, 3 -0.441 0.234 0.06 1.222 0.644 0.404 1 -0.25 0.551 0.65 0.187 0.779 0.271 2.19 -0.724 0.608 0.234 0.632 0.485 0.149 1.46 -0.976 0.691 0.158 0.802 0.377 0.0898 1.3 PRS_PLINK_0.000199526231496888 TRUE 585.34 Chronic Kidney Disease, Stage IV Both 26 40 11 genitourinary black 40, 26 10, 8 10, 11 10, 3 10, 4 -0.337 0.341 0.324 0.489 0.714 0.351 1.34 0.294 0.775 0.705 0.152 1.34 0.334 5.5 -0.742 1.11 0.504 0.298 0.476 0.0525 3.62 -1.31 1.23 0.286 0.544 0.269 0.0153 2.36 PRS_PLINK_0.000199526231496888 TRUE 585.4 Chronic kidney disease, Stage I or II Both 13 60 11 genitourinary black 60, 13 15, 9 15, 2 15, 1 15, 1 -0.558 0.334 0.0944 1.025 0.572 0.283 1.06 -1.15 0.885 0.195 0.711 0.317 0.0464 1.48 -2.34 1.15 0.0426 1.37 0.0965 0.00695 0.675 -1.49 0.985 0.131 0.882 0.226 0.0217 1.2 PRS_PLINK_0.000199526231496888 TRUE 586 Other disorders of the kidney and ureters Both 96 305 11 genitourinary black 305, 96 76, 28 76, 26 76, 29 76, 13 -0.151 0.126 0.233 0.632 0.86 0.671 1.1 0.0961 0.351 0.784 0.105 1.1 0.555 2.19 0.198 0.327 0.544 0.264 1.22 0.651 2.31 -0.64 0.409 0.117 0.93 0.527 0.232 1.15 PRS_PLINK_0.000199526231496888 FALSE 586.1 Anatomical abnormatilies of kidney and ureters Both 9 32 11 genitourinary black 32, 9 8, 3 8, 2 8, 2 8, 2 0.0629 0.503 0.9 0.046 1.06 0.414 2.87 -1.83 2 0.36 0.444 0.16 0.000257 10.8 -0.0878 1.46 0.952 0.021 0.916 0.0572 14.5 -0.664 1.6 0.678 0.169 0.515 0.0268 8.35 PRS_PLINK_0.000199526231496888 TRUE 586.11 Small kidney Both 4 18 11 genitourinary black 18, 4 5, 2 4, 0 4, 2 5, 0 -0.641 0.763 0.401 0.397 0.527 0.0363 2 -0.469 1.84 0.799 0.098 0.625 0.0255 13.7 0.321 3.65 0.93 0.032 1.38 0.00414 546 -0.778 3.55 0.826 0.083 0.459 0.00196 73.4 PRS_PLINK_0.000199526231496888 TRUE 586.12 Vesicoureteral reflux Both 6 13 11 genitourinary black 13, 6 4, 2 3, 2 3, 0 3, 2 -0.139 0.699 0.843 0.074 0.87 0.124 2.81 -2.74 5.76 0.633 0.198 0.0643 3.82e-07 213 3.03 18.5 0.87 0.06 20.7 16.8 25.3 -2.51 6.77 0.711 0.148 0.0817 8.14e-11 4950 PRS_PLINK_0.000199526231496888 TRUE 586.2 Cyst of kidney, acquired Both 16 67 11 genitourinary black 67, 16 17, 3 17, 7 16, 4 17, 2 -0.182 0.297 0.54 0.267 0.834 0.466 1.47 1.35 0.934 0.149 0.826 3.85 0.744 34.5 -0.423 1.06 0.689 0.162 0.655 0.0772 4.8 -0.103 1 0.918 0.037 0.902 0.0831 6.43 PRS_PLINK_0.000199526231496888 TRUE 586.3 Vascular disorders of kidney/hypertrophy Both 4 8 11 genitourinary black 8, 4 2, 1 2, 0 2, 0 2, 3 0.851 0.745 0.253 0.596 2.34 0.851 12 -0.543 7460000 1 0 0.581 0.0153 17 0.0036 28.3 1 0 1 0.742 1.24 3.6 124 0.977 0.01 36.5 39.2 49.1 PRS_PLINK_0.000199526231496888 TRUE 586.4 Stricture/obstruction of ureter Both 28 124 11 genitourinary black 124, 28 31, 10 31, 8 31, 7 31, 3 -0.23 0.221 0.298 0.525 0.794 0.51 1.22 0.0687 0.613 0.911 0.041 1.07 0.326 3.56 0.00133 0.59 0.998 0.001 1 0.321 3.15 -1.11 0.772 0.15 0.825 0.329 0.0599 1.37 PRS_PLINK_0.000199526231496888 TRUE 587 Kidney replaced by transpant Both 39 51 11 genitourinary black 51, 39 13, 17 13, 8 12, 8 13, 6 -0.0836 0.258 0.746 0.127 0.92 0.559 1.5 -0.939 0.801 0.241 0.617 0.391 0.0754 1.67 0.145 0.789 0.855 0.068 1.16 0.271 5.57 -0.951 0.891 0.286 0.544 0.386 0.0632 1.92 PRS_PLINK_0.000199526231496888 TRUE 588 Disorders resulting from impaired renal function Both 37 53 11 genitourinary black 53, 37 14, 17 13, 11 13, 4 13, 5 -0.156 0.251 0.536 0.271 0.856 0.525 1.38 -0.406 0.7 0.562 0.251 0.666 0.176 2.42 -0.893 0.824 0.278 0.555 0.409 0.0866 1.82 -0.764 0.952 0.423 0.374 0.466 0.0638 2.64 PRS_PLINK_0.000199526231496888 TRUE 588.1 Renal osteodystrophy Both 27 13 11 genitourinary black 13, 27 4, 11 3, 4 3, 6 3, 6 -0.0443 0.412 0.914 0.039 0.957 0.443 2.09 0.263 2.16 0.903 0.044 1.3 0.0523 7180000 -0.321 1.12 0.775 0.111 0.726 0.104 5.32 0.431 1.38 0.756 0.122 1.54 0.135 156 PRS_PLINK_0.000199526231496888 TRUE 588.2 Secondary hyperparathyroidism (of renal origin) Both 21 43 11 genitourinary black 43, 21 11, 5 11, 6 10, 5 11, 5 0.639 0.365 0.0798 1.098 1.89 0.987 4.4 0.865 1.13 0.443 0.354 2.37 0.291 33.8 1.26 1.26 0.319 0.497 3.52 0.44 97 1.61 1.29 0.211 0.675 5.02 0.554 44900 PRS_PLINK_0.000199526231496888 TRUE 589 Abnormal results of function study of kidney Both 22 53 11 genitourinary black 53, 22 14, 5 13, 6 13, 6 13, 5 -0.0588 0.302 0.846 0.073 0.943 0.524 1.67 -0.593 1.11 0.593 0.227 0.552 0.0343 4.15 0.498 0.875 0.57 0.244 1.64 0.337 9.52 -0.499 0.897 0.578 0.238 0.607 0.101 3.04 PRS_PLINK_0.000199526231496888 TRUE 590 Pyelonephritis Both 38 136 11 genitourinary black 136, 38 33, 9 34, 4 34, 17 34, 8 0.124 0.183 0.496 0.304 1.13 0.798 1.62 -0.968 0.703 0.169 0.773 0.38 0.0841 1.41 0.62 0.505 0.22 0.658 1.86 0.724 5.03 0.0368 0.586 0.95 0.022 1.04 0.33 3.21 PRS_PLINK_0.000199526231496888 TRUE 591 Urinary tract infection Both 175 237 11 genitourinary black 237, 175 59, 38 59, 25 59, 57 59, 55 0.225 0.104 0.0302 1.52 1.25 1.03 1.53 -0.414 0.331 0.21 0.677 0.661 0.348 1.24 0.471 0.289 0.103 0.986 1.6 0.923 2.8 0.422 0.298 0.157 0.805 1.53 0.864 2.71 PRS_PLINK_0.000199526231496888 FALSE 592 Cystitis and urethritis Both 62 213 11 genitourinary black 213, 62 53, 9 53, 19 53, 18 53, 16 0.211 0.153 0.168 0.775 1.24 0.92 1.67 0.682 0.455 0.134 0.872 1.98 0.836 4.94 0.742 0.446 0.0962 1.017 2.1 0.896 5.22 0.65 0.5 0.193 0.714 1.92 0.739 5.25 PRS_PLINK_0.000199526231496888 FALSE 592.1 Cystitis Both 57 211 11 genitourinary black 211, 57 52, 9 53, 17 52, 15 53, 16 0.229 0.157 0.145 0.839 1.26 0.93 1.72 0.603 0.467 0.196 0.708 1.83 0.755 4.66 0.67 0.463 0.148 0.83 1.95 0.805 4.99 0.774 0.509 0.128 0.891 2.17 0.825 6.16 PRS_PLINK_0.000199526231496888 FALSE 592.11 Acute cystitis Both 38 139 11 genitourinary black 139, 38 35, 5 35, 11 34, 11 35, 11 0.241 0.204 0.237 0.625 1.27 0.862 1.92 0.513 0.588 0.383 0.416 1.67 0.536 5.56 0.917 0.576 0.111 0.954 2.5 0.848 8.17 0.666 0.621 0.284 0.547 1.95 0.601 7.06 PRS_PLINK_0.000199526231496888 TRUE 592.12 Chronic cystitis Both 5 15 11 genitourinary black 15, 5 4, 0 4, 0 3, 1 4, 4 -0.207 1.11 0.853 0.069 0.813 0.00293 10.9 -0.0772 136 1 0 0.926 0.654 1.4 -2.38 7.29 0.744 0.128 0.0925 0.0806 544 PRS_PLINK_0.000199526231496888 TRUE 592.13 Chronic interstitial cystitis Both 4 52 11 genitourinary black 52, 4 12, 1 13, 1 13, 1 13, 1 -0.205 0.531 0.7 0.155 0.815 0.201 3.13 -0.0431 1.73 0.98 0.009 0.958 0.0058 33.9 -0.334 1.41 0.813 0.09 0.716 0.0148 24 -2.39 2.05 0.244 0.613 0.0917 0.000273 4.43 PRS_PLINK_0.000199526231496888 TRUE 592.2 Urethritis and urethral syndrome Both 6 16 11 genitourinary black 16, 6 4, 1 4, 1 4, 2 4, 2 0.144 0.669 0.83 0.081 1.15 0.36 5.6 1.28 8.56 0.881 0.055 3.61 3.4 3.86 -1.95 25.9 0.94 0.027 0.142 0.126 0.158 0.514 3.36 0.878 0.056 1.67 0.0116 465 PRS_PLINK_0.000199526231496888 TRUE 593 Hematuria Both 74 235 11 genitourinary black 235, 74 58, 19 59, 10 58, 24 59, 21 0.081 0.135 0.55 0.26 1.08 0.835 1.41 -0.498 0.441 0.259 0.587 0.608 0.251 1.41 0.294 0.37 0.427 0.369 1.34 0.66 2.76 0.302 0.381 0.427 0.369 1.35 0.653 2.83 PRS_PLINK_0.000199526231496888 FALSE 593.1 Gross hematuria Both 18 75 11 genitourinary black 75, 18 19, 4 19, 4 18, 6 19, 4 0.118 0.259 0.649 0.188 1.13 0.693 1.86 -0.369 1.05 0.726 0.139 0.691 0.0702 5.79 1.06 0.8 0.184 0.735 2.89 0.689 15.2 0.117 0.793 0.883 0.054 1.12 0.251 5.07 PRS_PLINK_0.000199526231496888 TRUE 593.2 Microscopic hematuria Both 14 65 11 genitourinary black 65, 14 17, 6 16, 4 16, 1 16, 3 -0.156 0.306 0.61 0.215 0.856 0.461 1.53 -0.156 0.879 0.86 0.066 0.856 0.147 4.37 -1.26 0.959 0.19 0.722 0.284 0.0299 1.59 -0.102 0.842 0.903 0.044 0.903 0.175 4.25 PRS_PLINK_0.000199526231496888 TRUE 594 Urinary calculus Both 71 365 11 genitourinary black 365, 71 91, 20 91, 16 91, 19 91, 16 -0.012 0.134 0.928 0.032 0.988 0.76 1.29 -0.391 0.38 0.303 0.518 0.676 0.316 1.42 0.0559 0.356 0.875 0.058 1.06 0.525 2.13 -0.324 0.387 0.402 0.395 0.723 0.331 1.54 PRS_PLINK_0.000199526231496888 FALSE 594.1 Calculus of kidney Both 65 366 11 genitourinary black 366, 65 91, 18 91, 15 91, 18 92, 14 -0.0229 0.139 0.869 0.061 0.977 0.744 1.29 -0.332 0.389 0.395 0.404 0.718 0.328 1.54 0.115 0.366 0.753 0.123 1.12 0.546 2.32 -0.314 0.4 0.433 0.364 0.731 0.325 1.6 PRS_PLINK_0.000199526231496888 FALSE 594.2 Calculus of lower urinary tract Both 3 27 11 genitourinary black 27, 3 7, 1 7, 2 6, 0 7, 0 -0.385 0.641 0.548 0.261 0.681 0.052 2.31 0.596 1.94 0.759 0.12 1.81 0.00646 620 0.974 3.21 0.761 0.118 2.65 0.00104 240000 -0.608 1.54 0.693 0.16 0.545 0.00572 14.6 PRS_PLINK_0.000199526231496888 TRUE 594.3 Calculus of ureter Both 22 108 11 genitourinary black 108, 22 27, 7 27, 3 27, 8 27, 4 -0.117 0.252 0.643 0.192 0.89 0.541 1.46 -0.826 0.743 0.266 0.575 0.438 0.0906 1.77 0.214 0.621 0.73 0.137 1.24 0.381 4.22 -1.06 0.797 0.183 0.738 0.345 0.0556 1.52 PRS_PLINK_0.000199526231496888 TRUE 594.8 Renal colic Both 5 38 11 genitourinary black 38, 5 10, 2 9, 1 9, 1 10, 1 -0.224 0.55 0.684 0.165 0.799 0.231 2.33 0.487 1.5 0.744 0.128 1.63 0.104 279 -0.829 1.4 0.555 0.256 0.437 0.00814 6.33 -0.712 1.42 0.617 0.21 0.491 0.0178 10.1 PRS_PLINK_0.000199526231496888 TRUE 595 Hydronephrosis Both 26 152 11 genitourinary black 152, 26 38, 9 38, 5 38, 6 38, 6 -0.225 0.232 0.333 0.478 0.799 0.499 1.26 -0.432 0.661 0.513 0.29 0.649 0.163 2.33 -0.354 0.602 0.556 0.255 0.702 0.21 2.25 -0.485 0.619 0.433 0.363 0.616 0.171 2.07 PRS_PLINK_0.000199526231496888 TRUE 596 Other disorders of bladder Both 36 228 11 genitourinary black 228, 36 56, 7 57, 8 57, 10 57, 11 0.139 0.181 0.441 0.356 1.15 0.809 1.65 0.312 0.583 0.593 0.227 1.37 0.43 4.59 0.368 0.549 0.503 0.299 1.45 0.493 4.48 0.453 0.553 0.413 0.385 1.57 0.535 4.87 PRS_PLINK_0.000199526231496888 TRUE 596.1 Bladder neck obstruction Both 4 14 11 genitourinary black 14, 4 4, 0 3, 2 3, 0 4, 2 0.281 0.574 0.624 0.205 1.32 0.526 470 -1.85 15.6 0.906 0.043 0.157 0.137 0.185 1.05 1.92 0.585 0.233 2.85 0.163 107 PRS_PLINK_0.000199526231496888 TRUE 596.5 Functional disorders of bladder Both 24 150 11 genitourinary black 150, 24 38, 7 37, 6 37, 5 38, 6 -0.131 0.256 0.609 0.215 0.878 0.523 1.44 -0.0662 0.657 0.92 0.036 0.936 0.253 3.56 -0.24 0.676 0.723 0.141 0.787 0.194 2.99 -0.307 0.712 0.667 0.176 0.736 0.169 3.09 PRS_PLINK_0.000199526231496888 TRUE 597 Other disorders of urethra and urinary tract Both 11 81 11 genitourinary black 81, 11 20, 1 20, 5 20, 3 20, 2 0.501 0.394 0.203 0.693 1.65 0.779 4.02 0.656 1.11 0.553 0.257 1.93 0.191 32.8 1.24 1.21 0.305 0.516 3.45 0.308 89.9 0.525 1.26 0.677 0.169 1.69 0.101 318000 PRS_PLINK_0.000199526231496888 TRUE 597.1 Urethral stricture (not specified as infectious) Both 7 27 11 genitourinary black 27, 7 7, 1 7, 4 6, 2 7, 0 0.186 0.581 0.749 0.126 1.2 0.419 3.76 1.85 2.15 0.391 0.408 6.35 0.0709 7230 1.05 1.69 0.533 0.273 2.87 0.145 67.3 0.501 1.75 0.775 0.111 1.65 0.0212 929 PRS_PLINK_0.000199526231496888 TRUE 597.2 Urinary complications NEC Both 12 74 11 genitourinary black 74, 12 19, 2 18, 2 18, 3 19, 5 0.429 0.372 0.249 0.603 1.54 0.768 3.28 -0.0286 1.02 0.978 0.01 0.972 0.111 8.3 0.553 0.898 0.538 0.269 1.74 0.313 10.9 0.542 0.885 0.54 0.267 1.72 0.345 10.7 PRS_PLINK_0.000199526231496888 TRUE 597.8 Urethral hypermobility/ISD Both 3 17 11 genitourinary black 17, 3 5, 0 4, 1 4, 0 4, 2 1.35 1.43 0.348 0.459 3.85 0.343 311 1.2e-14 4.51 1 0 1 0.000746 585 0.854 2.48 0.73 0.137 2.35 0.0227 2930 PRS_PLINK_0.000199526231496888 TRUE 598 Abnormal findings on examination of urine Both 2 11 11 genitourinary black 11, 2 3, 0 3, 1 2, 0 3, 1 0.169 5.92 0.977 0.01 1.18 0.00108 1170 0.00107 55.7 1 0 1 0.958 1.06 0.612 25300000 1 0 1.84 0.027 111 PRS_PLINK_0.000199526231496888 TRUE 598.4 Other cells and casts in urine Both 1 9 11 genitourinary black 9, 1 3, 0 2, 0 2, 0 2, 1 2.99e-12 24.5 1 0 1 0.000616 1.12 -0.238 2780 1 0 0.788 0.126 6.92 PRS_PLINK_0.000199526231496888 TRUE 599 Other symptoms/disorders or the urinary system Both 203 235 11 genitourinary black 235, 203 58, 49 59, 41 58, 55 59, 58 0.0707 0.101 0.483 0.316 1.07 0.884 1.31 -0.204 0.3 0.496 0.305 0.815 0.457 1.45 0.0544 0.286 0.849 0.071 1.06 0.61 1.83 0.171 0.289 0.554 0.257 1.19 0.681 2.07 PRS_PLINK_0.000199526231496888 FALSE 599.1 Urinary obstruction Both 8 27 11 genitourinary black 27, 8 7, 3 7, 3 6, 0 7, 2 -0.0974 0.501 0.846 0.073 0.907 0.287 2.28 -0.0187 1.42 0.989 0.005 0.981 0.0744 13 -2.09 2.22 0.348 0.458 0.124 0.000634 5.01 0.199 1.2 0.868 0.062 1.22 0.152 10.5 PRS_PLINK_0.000199526231496888 TRUE 599.2 Retention of urine Both 61 210 11 genitourinary black 210, 61 52, 15 52, 15 52, 12 53, 19 0.13 0.163 0.425 0.371 1.14 0.832 1.57 0.0816 0.463 0.86 0.065 1.08 0.446 2.66 -0.211 0.469 0.652 0.186 0.809 0.326 1.99 0.329 0.422 0.435 0.361 1.39 0.624 3.14 PRS_PLINK_0.000199526231496888 FALSE 599.3 Dysuria Both 99 227 11 genitourinary black 227, 99 56, 25 57, 24 56, 22 57, 28 0.0411 0.126 0.744 0.128 1.04 0.817 1.33 -0.273 0.379 0.472 0.326 0.761 0.364 1.57 -0.141 0.362 0.698 0.156 0.869 0.431 1.74 0.24 0.364 0.51 0.293 1.27 0.63 2.57 PRS_PLINK_0.000199526231496888 FALSE 599.4 Urinary incontinence Both 70 223 11 genitourinary black 223, 70 55, 20 56, 14 55, 18 56, 18 -0.0617 0.145 0.67 0.174 0.94 0.709 1.25 -0.206 0.421 0.624 0.205 0.814 0.357 1.82 -0.179 0.403 0.656 0.183 0.836 0.38 1.82 -0.0676 0.415 0.871 0.06 0.935 0.416 2.08 PRS_PLINK_0.000199526231496888 FALSE 599.5 Frequency of urination and polyuria Both 84 234 11 genitourinary black 234, 84 58, 18 58, 15 58, 27 59, 24 0.155 0.139 0.266 0.575 1.17 0.893 1.53 -0.212 0.438 0.628 0.202 0.809 0.344 1.88 0.352 0.383 0.359 0.445 1.42 0.681 3.01 0.384 0.399 0.336 0.474 1.47 0.685 3.19 PRS_PLINK_0.000199526231496888 FALSE 599.6 Oliguria and anuria Both 5 24 11 genitourinary black 24, 5 6, 2 6, 0 6, 1 6, 2 -0.236 0.664 0.723 0.141 0.79 0.222 2.87 -2.14 2.43 0.378 0.423 0.117 1.56e-05 4.59 0.281 2.26 0.901 0.045 1.32 0.00645 2870 -1.51 2.05 0.46 0.338 0.22 1.73e-08 10.7 PRS_PLINK_0.000199526231496888 TRUE 599.7 Urethral discharge Both 0 2 11 genitourinary black 2, 0 1 1 1 1 PRS_PLINK_0.000199526231496888 TRUE 599.8 Other symptoms involving urinary system Both 64 224 11 genitourinary black 224, 64 55, 18 56, 13 56, 17 56, 16 -0.0831 0.151 0.581 0.236 0.92 0.686 1.24 -0.23 0.424 0.588 0.231 0.794 0.346 1.79 -0.0896 0.408 0.826 0.083 0.914 0.411 2.03 -0.141 0.433 0.745 0.128 0.868 0.371 2 PRS_PLINK_0.000199526231496888 FALSE 599.9 Other abnormality of urination Both 42 195 11 genitourinary black 195, 42 48, 11 49, 8 48, 12 49, 11 0.0651 0.177 0.713 0.147 1.07 0.757 1.51 -0.412 0.528 0.435 0.362 0.662 0.229 1.82 0.143 0.478 0.766 0.116 1.15 0.455 2.95 0.118 0.502 0.814 0.089 1.13 0.427 2.96 PRS_PLINK_0.000199526231496888 TRUE 600 Hyperplasia of prostate Male 18 42 11 genitourinary black 42, 18 11, 4 10, 4 10, 4 11, 6 0.223 0.329 0.499 0.302 1.25 0.688 2.38 0.509 1.14 0.655 0.183 1.66 0.185 24.1 0.246 1.09 0.821 0.086 1.28 0.16 17.8 -0.332 1.19 0.78 0.108 0.717 0.6 5.95 PRS_PLINK_0.000199526231496888 TRUE 601 Inflammatory diseases of prostate Male 5 31 11 genitourinary black 31, 5 8, 0 8, 1 7, 1 8, 3 0.373 0.485 0.442 0.355 1.45 0.464 16 0.299 1.73 0.863 0.064 1.35 0.000421 90.3 1.04 1.81 0.564 0.249 2.84 0.00355 562 0.976 1.51 0.517 0.286 2.65 0.172 1180 PRS_PLINK_0.000199526231496888 TRUE 601.1 Prostatitis Male 3 15 11 genitourinary black 15, 3 4, 0 4, 1 3, 0 4, 2 -0.224 0.675 0.739 0.131 0.799 0.0964 3.62 -0.0893 3 0.976 0.01 0.915 0.0035 134 1.12 3.39 0.742 0.13 3.05 0.021 505 PRS_PLINK_0.000199526231496888 TRUE 601.11 Acute prostatitis Male 1 7 11 genitourinary black 7, 1 2, 0 2, 0 1, 0 2, 1 0.139 66.6 0.998 0.001 1.15 0.122 67.3 -0.104 2760000 1 0 0.902 0.189 1.48 PRS_PLINK_0.000199526231496888 TRUE 601.12 Chronic prostatitis Male 0 4 11 genitourinary black 4, 0 1 1 1 1 PRS_PLINK_0.000199526231496888 TRUE 601.3 Orchitis and epididymitis Male 3 13 11 genitourinary black 13, 3 4, 0 3, 0 3, 1 3, 2 0.702 1.02 0.492 0.308 2.02 0.362 3410 -0.052 48.7 0.999 0 0.949 0.0646 2030 0.311 3.64 0.932 0.031 1.37 0.0059 2880 PRS_PLINK_0.000199526231496888 TRUE 601.4 Balanoposthitis Male 0 3 11 genitourinary black 3, 0 1 1 1 1 PRS_PLINK_0.000199526231496888 TRUE 601.8 Other inflammatory disorders of male genital organs Male 1 3 11 genitourinary black 3, 1 1, 0 1, 0 0, 1 1, 0 -0.692 43100000 1 0 0.501 0.0172 8.46 0.00139 20.8 1 0 1 0.972 1.03 PRS_PLINK_0.000199526231496888 TRUE 602 Other disorders of prostate Male 3 9 11 genitourinary black 9, 3 3, 1 2, 1 2, 0 2, 1 -0.939 1.06 0.376 0.425 0.391 0.00128 1.78 -1.32 141 0.993 0.003 0.267 0.049 1.76 0.132 103 0.999 0 1.14 0.922 1.92 -1.52 274 0.996 0.002 0.219 0.00126 0.00644 PRS_PLINK_0.000199526231496888 TRUE 602.3 Dysplasia of prostate Male 1 2 11 genitourinary black 2, 1 1, 1 1, 0 1, 1 1, 0 -0.011 4440 1 0 0.989 0.667 1.29 -0.0194 22900 1 0 0.981 0.281 3.67 PRS_PLINK_0.000199526231496888 TRUE 603 Other disorders of testis Male 1 7 11 genitourinary black 7, 1 2, 0 2, 0 1, 0 2, 1 0.278 2.1 0.895 0.048 1.32 0.0392 27.3 -0.0506 2260 1 0 0.951 0.358 2.25 PRS_PLINK_0.000199526231496888 TRUE 603.1 Hydrocele Male 0 7 11 genitourinary black 7, 0 2 2 1 2 PRS_PLINK_0.000199526231496888 TRUE 603.2 Spermatocele Male 1 2 11 genitourinary black 2, 1 1, 0 1, 1 1, 0 1, 1 0.0369 827 1 0 1.04 0.918 1.32 0.627 4960 1 0 1.87 0.525 1.91 PRS_PLINK_0.000199526231496888 TRUE 604 Disorders of penis Male 5 18 11 genitourinary black 18, 5 5, 1 4, 3 4, 1 5, 0 -0.696 0.721 0.335 0.475 0.499 0.113 1.62 1.77 1.74 0.309 0.509 5.88 0.49 4640000 -0.257 1.87 0.891 0.05 0.773 0.00728 31.3 -0.203 3.04 0.947 0.024 0.816 0.000352 84.5 PRS_PLINK_0.000199526231496888 TRUE 604.1 Redundant prepuce and phimosis/BXO Male 0 2 11 genitourinary black 2, 0 1 1 1 1 PRS_PLINK_0.000199526231496888 TRUE 604.3 Peyronie's disease Male 2 7 11 genitourinary black 7, 2 2, 1 2, 1 1, 0 2, 0 0.203 6530000 1 0 1.22 0.00518 8.32 -0.269 1870 1 0 0.764 0.0608 5.35 -0.868 20600 1 0 0.42 0.0264 7.98 0.0908 2620 1 0 1.1 0.388 1.87 PRS_PLINK_0.000199526231496888 TRUE 605 Erectile dysfunction [ED] Male 18 41 11 genitourinary black 41, 18 11, 2 10, 6 10, 6 10, 4 0.275 0.301 0.361 0.443 1.32 0.762 2.34 0.93 1.01 0.357 0.447 2.53 0.427 21.8 0.798 1.01 0.429 0.367 2.22 0.337 16.9 0.513 1.14 0.651 0.186 1.67 0.22 29.9 PRS_PLINK_0.000199526231496888 TRUE 608 Other disorders of male genital organs Male 8 45 11 genitourinary black 45, 8 12, 2 11, 0 11, 3 11, 3 0.431 0.405 0.288 0.541 1.54 0.749 3.84 -0.488 1.74 0.78 0.108 0.614 5.61e-05 359 -1.06 1.84 0.565 0.248 0.347 0.000154 23.4 0.366 1.1 0.739 0.131 1.44 0.185 12.2 PRS_PLINK_0.000199526231496888 TRUE 609 Male infertility and abnormal spermatozoa Male 2 11 11 genitourinary black 11, 2 3, 0 3, 0 2, 2 3, 0 0.252 1.05 0.811 0.091 1.29 0.231 7.26 0.434 537 0.999 0 1.54 0.815 3.67 PRS_PLINK_0.000199526231496888 TRUE 609.1 Infertility, male Male 2 9 11 genitourinary black 9, 2 3, 0 2, 0 2, 2 2, 0 1.22 4.25 0.774 0.111 3.39 0.0013 3920 0.0713 50.9 0.999 0 1.07 0.00497 150 PRS_PLINK_0.000199526231496888 TRUE 609.11 Azoospermia and oligospermia Male 0 4 11 genitourinary black 4, 0 1 1 1 1 PRS_PLINK_0.000199526231496888 TRUE 609.2 Abnormal spermatozoa Male 0 3 11 genitourinary black 3, 0 1 1 1 1 PRS_PLINK_0.000199526231496888 TRUE 610 Benign mammary dysplasias Female 76 195 11 genitourinary black 195, 76 49, 19 49, 19 48, 20 49, 17 -0.199 0.16 0.214 0.67 0.82 0.599 1.12 0.0464 0.459 0.92 0.036 1.05 0.43 2.56 0.0502 0.462 0.913 0.039 1.05 0.431 2.57 -0.115 0.455 0.801 0.097 0.891 0.367 2.15 PRS_PLINK_0.000199526231496888 FALSE 610.1 Cystic mastopathy Female 34 136 11 genitourinary black 136, 34 34, 12 34, 10 34, 6 34, 6 -0.208 0.213 0.33 0.481 0.812 0.533 1.23 -0.179 0.579 0.757 0.121 0.836 0.269 2.56 -0.975 0.701 0.164 0.784 0.377 0.0888 1.38 -0.4 0.637 0.531 0.275 0.67 0.185 2.3 PRS_PLINK_0.000199526231496888 TRUE 610.2 Fibroadenosis of breast Female 1 9 11 genitourinary black 9, 1 3, 0 2, 0 2, 0 2, 1 0.681 0.842 0.419 0.378 1.98 0.663 20.8 0.207 1480 1 0 1.23 0.581 6.01 PRS_PLINK_0.000199526231496888 TRUE 610.4 Benign neoplasm of breast Female 58 192 11 genitourinary black 192, 58 48, 13 48, 14 48, 17 48, 13 -0.244 0.18 0.177 0.753 0.784 0.549 1.11 0.102 0.511 0.841 0.075 1.11 0.41 3.03 0.362 0.504 0.473 0.325 1.44 0.552 3.87 -0.192 0.524 0.713 0.147 0.825 0.294 2.26 PRS_PLINK_0.000199526231496888 FALSE 610.8 Other specified benign mammary dysplasias Female 24 113 11 genitourinary black 113, 24 29, 8 28, 8 28, 3 28, 5 -0.0879 0.242 0.717 0.145 0.916 0.566 1.47 0.169 0.664 0.799 0.097 1.18 0.329 4.41 -2.28 1.16 0.0482 1.317 0.102 0.00685 0.756 0.101 0.745 0.892 0.05 1.11 0.249 4.94 PRS_PLINK_0.000199526231496888 TRUE 611 Abnormal findings on mammogram or breast exam Both 141 205 11 genitourinary black 205, 141 52, 31 51, 33 51, 35 51, 41 -0.00451 0.122 0.971 0.013 0.995 0.785 1.26 0.00599 0.361 0.987 0.006 1.01 0.502 2.02 0.0738 0.371 0.842 0.074 1.08 0.526 2.21 0.322 0.346 0.352 0.454 1.38 0.712 2.7 PRS_PLINK_0.000199526231496888 FALSE 611.1 Abnormal mammogram Both 103 184 11 genitourinary black 184, 103 46, 23 46, 27 46, 26 46, 26 -0.0701 0.147 0.635 0.197 0.932 0.699 1.24 0.254 0.405 0.531 0.275 1.29 0.593 2.84 0.169 0.418 0.687 0.163 1.18 0.532 2.66 0.192 0.415 0.644 0.191 1.21 0.545 2.71 PRS_PLINK_0.000199526231496888 FALSE 611.11 Mammographic microcalcification Both 20 58 11 genitourinary black 58, 20 15, 5 14, 4 14, 7 15, 4 0.0508 0.306 0.868 0.061 1.05 0.581 1.89 0.479 0.922 0.604 0.219 1.61 0.293 11.5 -0.124 0.806 0.877 0.057 0.883 0.191 3.82 0.16 0.948 0.866 0.063 1.17 0.183 7.32 PRS_PLINK_0.000199526231496888 TRUE 611.3 Lump or mass in breast Both 91 203 11 genitourinary black 203, 91 51, 19 51, 23 50, 20 51, 28 -0.0715 0.135 0.597 0.224 0.931 0.716 1.21 0.0683 0.409 0.867 0.062 1.07 0.487 2.36 -0.175 0.451 0.697 0.157 0.839 0.348 2 0.329 0.385 0.393 0.406 1.39 0.666 2.93 PRS_PLINK_0.000199526231496888 FALSE 612 Breast conditions, congenital or relating to hormones Both 24 116 11 genitourinary black 116, 24 29, 7 29, 5 29, 5 29, 7 -0.00731 0.273 0.979 0.009 0.993 0.579 1.71 -0.515 0.68 0.448 0.348 0.597 0.149 2.16 -0.232 0.724 0.749 0.125 0.793 0.183 3.31 -0.107 0.694 0.877 0.057 0.898 0.232 3.47 PRS_PLINK_0.000199526231496888 TRUE 612.1 Galactorrhea Both 4 32 11 genitourinary black 32, 4 8, 0 8, 0 8, 2 8, 2 0.716 0.595 0.229 0.641 2.05 0.66 11.1 1.17 1.66 0.482 0.317 3.21 0.0671 1.53e+08 1.54 1.71 0.367 0.435 4.66 0.131 523 PRS_PLINK_0.000199526231496888 TRUE 612.2 Hypertrophy of breast (Gynecomastia) Both 18 64 11 genitourinary black 64, 18 16, 6 16, 3 16, 5 16, 4 -0.0979 0.334 0.769 0.114 0.907 0.478 1.76 -0.361 0.827 0.663 0.179 0.697 0.131 3.37 -0.508 0.81 0.531 0.275 0.602 0.119 2.59 -0.423 0.918 0.645 0.191 0.655 0.117 3.52 PRS_PLINK_0.000199526231496888 TRUE 612.3 Congenital anomalies of breast Both 2 19 11 genitourinary black 19, 2 5, 1 5, 0 4, 0 5, 1 0.493 1.06 0.643 0.192 1.64 0.272 144 -0.0938 1.78 0.958 0.019 0.91 0.0378 36.7 -0.708 28.7 0.98 0.009 0.493 0.00206 0.611 0.454 1.64 0.782 0.107 1.57 0.122 144 PRS_PLINK_0.000199526231496888 TRUE 613 Other nonmalignant breast conditions Both 99 281 11 genitourinary black 281, 99 71, 26 70, 19 70, 29 70, 24 -0.128 0.124 0.303 0.518 0.88 0.69 1.12 -0.31 0.358 0.386 0.413 0.733 0.362 1.46 -0.0585 0.336 0.862 0.065 0.943 0.492 1.8 -0.0918 0.346 0.791 0.102 0.912 0.465 1.78 PRS_PLINK_0.000199526231496888 FALSE 613.1 Inflammatory disease of breast Both 28 73 11 genitourinary black 73, 28 19, 8 18, 11 18, 5 18, 4 -0.227 0.242 0.348 0.459 0.797 0.499 1.25 0.218 0.692 0.753 0.123 1.24 0.339 4.75 -0.841 0.758 0.267 0.574 0.431 0.0969 1.66 -0.536 0.786 0.495 0.305 0.585 0.118 2.53 PRS_PLINK_0.000199526231496888 TRUE 613.5 Mastodynia Both 48 211 11 genitourinary black 211, 48 53, 11 53, 5 52, 16 53, 16 0.15 0.166 0.368 0.435 1.16 0.842 1.62 -0.877 0.617 0.155 0.809 0.416 0.114 1.33 0.258 0.449 0.566 0.247 1.29 0.545 3.16 0.473 0.457 0.301 0.522 1.6 0.671 3.96 PRS_PLINK_0.000199526231496888 TRUE 613.7 Other signs and symptoms in breast Both 31 118 11 genitourinary black 118, 31 30, 3 29, 10 29, 9 30, 8 -0.0601 0.214 0.779 0.108 0.942 0.624 1.43 1.11 0.687 0.107 0.971 3.03 0.842 13.3 0.87 0.66 0.188 0.727 2.39 0.698 9.96 0.645 0.694 0.352 0.453 1.91 0.498 8.35 PRS_PLINK_0.000199526231496888 TRUE 613.8 Other specified disorders of breast Both 21 130 11 genitourinary black 130, 21 33, 5 32, 4 32, 8 33, 4 -0.341 0.271 0.209 0.679 0.711 0.411 1.21 -0.622 0.714 0.384 0.416 0.537 0.11 2.19 0.179 0.62 0.772 0.112 1.2 0.361 4.13 -0.753 0.766 0.326 0.487 0.471 0.0851 2.09 PRS_PLINK_0.000199526231496888 TRUE 613.9 Breast disorder NOS Both 24 138 11 genitourinary black 138, 24 35, 5 34, 5 34, 8 35, 5 -0.181 0.232 0.434 0.363 0.834 0.53 1.31 -0.076 0.696 0.913 0.039 0.927 0.224 3.69 0.493 0.63 0.434 0.363 1.64 0.498 5.79 -0.416 0.771 0.589 0.23 0.66 0.141 2.89 PRS_PLINK_0.000199526231496888 TRUE 614 Inflammatory diseases of female pelvic organs Female 164 194 11 genitourinary black 194, 164 48, 45 48, 42 48, 49 49, 28 -0.132 0.114 0.246 0.609 0.876 0.702 1.09 -0.131 0.314 0.676 0.17 0.877 0.479 1.6 0.145 0.309 0.638 0.195 1.16 0.64 2.1 -0.463 0.343 0.178 0.75 0.63 0.322 1.21 PRS_PLINK_0.000199526231496888 FALSE 614.1 Pelvic peritoneal adhesions, female (postoperative) (postinfection) Female 14 31 11 genitourinary black 31, 14 7, 7 8, 3 7, 2 8, 2 -0.254 0.402 0.527 0.278 0.775 0.357 1.63 -0.653 1.06 0.536 0.271 0.521 0.0546 3.39 -1.05 1.14 0.357 0.447 0.349 0.0242 2.3 -1.59 1.32 0.23 0.638 0.205 0.0116 1.78 PRS_PLINK_0.000199526231496888 TRUE 614.3 Pelvic inflammatory disease (PID) Female 23 62 11 genitourinary black 62, 23 15, 6 15, 3 15, 7 16, 7 0.0577 0.284 0.839 0.076 1.06 0.62 1.86 -0.318 0.986 0.747 0.127 0.727 0.0981 5.17 0.259 0.794 0.744 0.128 1.3 0.269 6.34 0.258 0.823 0.753 0.123 1.29 0.288 6.45 PRS_PLINK_0.000199526231496888 TRUE 614.31 Acute inflammatory pelvic disease Female 6 13 11 genitourinary black 13, 6 4, 2 3, 0 3, 3 3, 1 -0.677 0.813 0.405 0.392 0.508 0.454 1.76 5.19 21.2 0.806 0.093 180 121 262 -0.524 2.5 0.834 0.079 0.592 0.000101 343 -4.05 7.91 0.608 0.216 0.0174 0.0123 484 PRS_PLINK_0.000199526231496888 TRUE 614.32 Chronic inflammatory pelvic disease Female 9 20 11 genitourinary black 20, 9 5, 1 5, 2 5, 2 5, 4 0.556 0.712 0.435 0.361 1.74 0.413 7.86 1.94 2.21 0.382 0.418 6.94 0.169 61200 0.976 1.62 0.547 0.262 2.65 0.18 79.4 1.23 1.71 0.472 0.326 3.42 0.208 916 PRS_PLINK_0.000199526231496888 TRUE 614.33 Pelvic inflammatory disease, NOS Female 13 37 11 genitourinary black 37, 13 10, 5 9, 2 9, 4 9, 2 0.0646 0.38 0.865 0.063 1.07 0.515 2.21 -1.35 1.25 0.282 0.55 0.26 0.0174 2.18 0.0804 1.04 0.938 0.028 1.08 0.121 7.74 -0.395 1.1 0.72 0.142 0.674 0.0772 4.73 PRS_PLINK_0.000199526231496888 TRUE 614.4 Inflammatory diseases of uterus, except cervix Female 15 27 11 genitourinary black 27, 15 6, 6 7, 3 6, 3 7, 3 -0.00307 0.329 0.993 0.003 0.997 0.539 1.8 -0.768 1.49 0.606 0.217 0.464 0.0117 5.88 -0.512 1.43 0.72 0.142 0.599 0.0453 6.49 0.0602 1.42 0.966 0.015 1.06 0.0935 20.4 PRS_PLINK_0.000199526231496888 TRUE 614.5 Inflammatory disease of cervix, vagina, and vulva Female 143 194 11 genitourinary black 194, 143 48, 40 48, 36 48, 44 49, 23 -0.129 0.119 0.279 0.555 0.879 0.697 1.11 -0.173 0.326 0.597 0.224 0.841 0.449 1.57 0.21 0.321 0.513 0.29 1.23 0.667 2.3 -0.495 0.363 0.173 0.763 0.61 0.3 1.22 PRS_PLINK_0.000199526231496888 FALSE 614.51 Cervicitis and endocervicitis Female 16 40 11 genitourinary black 40, 16 10, 5 10, 4 10, 5 10, 2 -0.324 0.322 0.314 0.502 0.723 0.376 1.31 0.0464 1.32 0.972 0.012 1.05 0.103 15.6 0.276 0.973 0.777 0.11 1.32 0.217 8.76 -0.556 1.38 0.687 0.163 0.574 0.0359 7.82 PRS_PLINK_0.000199526231496888 TRUE 614.52 Vaginitis and vulvovaginitis Female 118 191 11 genitourinary black 191, 118 47, 29 48, 32 47, 37 48, 20 -0.0696 0.126 0.581 0.236 0.933 0.731 1.19 0.0582 0.35 0.868 0.062 1.06 0.543 2.07 0.463 0.346 0.182 0.741 1.59 0.822 3.12 -0.339 0.388 0.382 0.418 0.712 0.334 1.49 PRS_PLINK_0.000199526231496888 FALSE 614.53 Cyst or abscess of Bartholin's gland Female 4 10 11 genitourinary black 10, 4 3, 3 2, 0 2, 1 3, 0 -0.305 0.731 0.677 0.17 0.737 0.158 2.38 -0.873 9.65 0.928 0.032 0.418 0.372 174 -0.00854 6.36 0.999 0 0.991 7.45e-05 34000 -2.89 21 0.891 0.05 0.0557 0.0499 22.4 PRS_PLINK_0.000199526231496888 TRUE 614.54 Abscess or ulceration of vulva Female 4 27 11 genitourinary black 27, 4 6, 2 7, 2 6, 0 7, 0 -0.373 0.45 0.407 0.39 0.689 0.27 1.82 0.127 1.25 0.919 0.037 1.14 0.116 18.3 -1.9 2.25 0.399 0.4 0.15 0.0021 15.1 -2.34 2.12 0.271 0.567 0.0965 2e-07 2.3 PRS_PLINK_0.000199526231496888 TRUE 615 Endometriosis Female 44 163 11 genitourinary black 163, 44 40, 11 41, 14 40, 10 41, 9 -0.149 0.177 0.402 0.396 0.862 0.61 1.22 0.208 0.491 0.672 0.173 1.23 0.483 3.18 0.0285 0.519 0.956 0.019 1.03 0.378 2.81 -0.181 0.564 0.749 0.126 0.835 0.278 2.47 PRS_PLINK_0.000199526231496888 TRUE 618 Genital prolapse Female 45 222 11 genitourinary black 222, 45 55, 14 55, 11 55, 12 56, 8 -0.141 0.168 0.401 0.396 0.868 0.622 1.21 -0.241 0.439 0.583 0.235 0.786 0.327 1.85 -0.221 0.437 0.613 0.213 0.801 0.338 1.87 -0.665 0.496 0.18 0.745 0.514 0.187 1.33 PRS_PLINK_0.000199526231496888 TRUE 618.1 Prolapse of vaginal walls Female 25 128 11 genitourinary black 128, 25 31, 7 32, 7 32, 6 32, 5 -0.0348 0.221 0.875 0.058 0.966 0.627 1.5 0.285 0.629 0.651 0.187 1.33 0.39 4.8 -0.196 0.594 0.741 0.13 0.822 0.253 2.61 -0.517 0.699 0.46 0.338 0.596 0.143 2.29 PRS_PLINK_0.000199526231496888 TRUE 618.2 Uterine/Uterovaginal prolapse Female 5 52 11 genitourinary black 52, 5 12, 1 13, 0 13, 2 13, 2 0.261 0.505 0.605 0.218 1.3 0.508 5.39 -0.495 1.35 0.714 0.146 0.609 0.00485 26.5 0.642 1.18 0.587 0.232 1.9 0.202 33.1 0.384 1.28 0.765 0.116 1.47 0.119 24.2 PRS_PLINK_0.000199526231496888 TRUE 618.5 Prolapse of vaginal vault after hysterectomy Female 1 11 11 genitourinary black 11, 1 3, 1 3, 0 2, 0 3, 0 -0.259 0.593 0.662 0.179 0.772 0.137 3.6 -1.56 449 0.997 0.001 0.209 5.41e-06 2080 -0.291 19500 1 0 0.747 0.00086 38.9 -0.774 78.7 0.992 0.003 0.461 0.00315 68.9 PRS_PLINK_0.000199526231496888 TRUE 618.6 Vaginal enterocele, congenital or acquired Female 12 51 11 genitourinary black 51, 12 13, 5 13, 3 12, 3 13, 1 -0.383 0.369 0.3 0.523 0.682 0.32 1.43 0.0934 1.02 0.927 0.033 1.1 0.151 8.32 0.0781 1.09 0.943 0.026 1.08 0.0334 11.7 -1.69 1.28 0.187 0.729 0.185 0.00823 1.55 PRS_PLINK_0.000199526231496888 TRUE 619 Noninflammatory female genital disorders Female 221 155 11 genitourinary black 155, 221 39, 67 39, 62 38, 49 39, 42 -0.284 0.115 0.0138 1.86 0.753 0.6 0.939 -0.149 0.313 0.635 0.198 0.862 0.468 1.58 -0.277 0.315 0.38 0.42 0.758 0.413 1.39 -0.603 0.342 0.0779 1.109 0.547 0.281 1.05 PRS_PLINK_0.000199526231496888 FALSE 619.1 Noninflammatory disorders of ovary, fallopian tube, and broad ligament Female 45 128 11 genitourinary black 128, 45 32, 14 32, 12 32, 11 32, 8 -0.269 0.191 0.158 0.803 0.764 0.527 1.1 -0.28 0.53 0.597 0.224 0.756 0.272 2.05 0.0956 0.525 0.856 0.068 1.1 0.406 3.04 -0.899 0.63 0.154 0.813 0.407 0.113 1.3 PRS_PLINK_0.000199526231496888 TRUE 619.2 Disorders of uterus, NEC Female 31 56 11 genitourinary black 56, 31 14, 9 14, 7 14, 7 14, 8 -0.3 0.25 0.231 0.637 0.741 0.457 1.17 -0.238 0.688 0.729 0.137 0.788 0.217 2.74 -0.289 0.74 0.696 0.157 0.749 0.187 2.93 -0.478 0.789 0.544 0.264 0.62 0.134 2.67 PRS_PLINK_0.000199526231496888 TRUE 619.3 Noninflammatory disorders of cervix Female 23 60 11 genitourinary black 60, 23 15, 4 15, 10 15, 6 15, 3 -0.21 0.305 0.49 0.309 0.81 0.439 1.43 0.75 0.812 0.356 0.449 2.12 0.481 11.5 0.471 0.792 0.552 0.258 1.6 0.378 7.77 -0.808 0.985 0.412 0.385 0.446 0.0519 2.63 PRS_PLINK_0.000199526231496888 TRUE 619.4 Noninflammatory disorders of vagina Female 114 153 11 genitourinary black 153, 114 39, 38 38, 30 38, 24 38, 22 -0.302 0.144 0.0352 1.453 0.739 0.557 0.972 -0.186 0.375 0.62 0.208 0.83 0.403 1.7 -0.276 0.39 0.48 0.319 0.759 0.358 1.6 -0.487 0.42 0.246 0.609 0.614 0.271 1.37 PRS_PLINK_0.000199526231496888 FALSE 619.5 Noninflammatory disorders of vulva and perineum Female 33 102 11 genitourinary black 102, 33 26, 9 25, 12 25, 8 26, 4 -0.327 0.223 0.142 0.848 0.721 0.464 1.1 0.207 0.565 0.714 0.146 1.23 0.421 3.67 -0.465 0.62 0.453 0.344 0.628 0.182 1.98 -1.07 0.752 0.157 0.805 0.344 0.0697 1.36 PRS_PLINK_0.000199526231496888 TRUE 620 Dysplasia of female genital organs Female 14 66 11 genitourinary black 66, 14 17, 3 16, 5 16, 2 17, 4 0.125 0.305 0.681 0.167 1.13 0.638 2.06 0.49 0.86 0.569 0.245 1.63 0.335 8.8 1.1 1.45 0.446 0.351 3.02 0.198 86 0.182 1.03 0.86 0.065 1.2 0.154 9.51 PRS_PLINK_0.000199526231496888 TRUE 620.1 Dysplasia of cervix Female 9 39 11 genitourinary black 39, 9 10, 2 10, 2 9, 3 10, 2 -0.29 0.397 0.464 0.333 0.748 0.348 1.6 -0.413 1.13 0.716 0.145 0.662 0.0663 5.1 -0.167 1.07 0.876 0.057 0.846 0.665 16.8 -1.13 1.81 0.531 0.275 0.322 0.00471 7.82 PRS_PLINK_0.000199526231496888 TRUE 621 Endometrial hyperplasia Female 17 49 11 genitourinary black 49, 17 12, 6 12, 6 12, 2 12, 3 -0.289 0.347 0.406 0.391 0.749 0.384 1.45 0.44 0.87 0.613 0.213 1.55 0.322 7.99 -0.695 1.06 0.511 0.291 0.499 0.0576 3.27 -0.763 1.1 0.488 0.311 0.466 0.051 3.19 PRS_PLINK_0.000199526231496888 TRUE 622 Polyp of female genital organs Female 47 189 11 genitourinary black 189, 47 47, 14 47, 12 47, 9 47, 12 0.0341 0.174 0.844 0.074 1.03 0.737 1.46 -0.105 0.46 0.82 0.086 0.9 0.366 2.19 -0.462 0.477 0.333 0.478 0.63 0.242 1.57 0.069 0.463 0.882 0.055 1.07 0.435 2.66 PRS_PLINK_0.000199526231496888 TRUE 622.1 Polyp of corpus uteri Female 34 141 11 genitourinary black 141, 34 35, 10 35, 10 35, 6 35, 8 -0.0781 0.2 0.696 0.157 0.925 0.623 1.37 0.197 0.54 0.715 0.146 1.22 0.431 3.51 -0.357 0.565 0.528 0.278 0.7 0.223 2.11 -0.0704 0.555 0.899 0.046 0.932 0.315 2.76 PRS_PLINK_0.000199526231496888 TRUE 622.2 Mucous polyp of cervix Female 16 50 11 genitourinary black 50, 16 13, 3 12, 3 12, 3 13, 7 0.336 0.349 0.335 0.475 1.4 0.733 2.8 0.18 1.04 0.863 0.064 1.2 0.158 9.09 -0.146 1.24 0.906 0.043 0.864 0.0797 10.2 0.974 1.01 0.335 0.475 2.65 0.442 22.5 PRS_PLINK_0.000199526231496888 TRUE 623 Hypertrophy of female genital organs Female 18 110 11 genitourinary black 110, 18 27, 5 27, 3 27, 6 28, 4 -0.0798 0.233 0.732 0.136 0.923 0.579 1.47 0.786 0.936 0.401 0.397 2.2 0.319 17.9 0.143 0.718 0.842 0.075 1.15 0.28 4.72 -0.00708 0.843 0.993 0.003 0.993 0.164 5.91 PRS_PLINK_0.000199526231496888 TRUE 624 Symptoms involving female genital tract Female 70 130 11 genitourinary black 130, 70 32, 17 32, 16 32, 21 33, 16 0.0421 0.16 0.792 0.101 1.04 0.769 1.42 0.0391 0.477 0.935 0.029 1.04 0.421 2.55 0.365 0.458 0.426 0.371 1.44 0.609 3.45 0.108 0.474 0.819 0.087 1.11 0.454 2.76 PRS_PLINK_0.000199526231496888 FALSE 624.1 Dystrophy of female genital tract Female 5 15 11 genitourinary black 15, 5 4, 1 4, 1 3, 1 4, 2 0.0964 0.589 0.87 0.06 1.1 0.369 3.92 1.24 3.11 0.691 0.161 3.45 0.0316 371 0.172 2.16 0.937 0.028 1.19 0.0345 46.2 1.08 2.58 0.676 0.17 2.94 0.0587 4.1e+07 PRS_PLINK_0.000199526231496888 TRUE 624.2 Atrophy of female genital tract Female 0 6 11 genitourinary black 6, 0 2 1 1 2 PRS_PLINK_0.000199526231496888 TRUE 624.9 stress incontinence, female Female 54 119 11 genitourinary black 119, 54 29, 14 30, 13 29, 15 30, 12 -0.062 0.173 0.72 0.143 0.94 0.674 1.31 -0.0751 0.499 0.88 0.055 0.928 0.358 2.38 0.028 0.491 0.955 0.02 1.03 0.406 2.62 0.0277 0.512 0.957 0.019 1.03 0.389 2.74 PRS_PLINK_0.000199526231496888 FALSE 625 Pain and other symptoms associated with female genital organs Female 191 144 11 genitourinary black 144, 191 35, 47 36, 47 36, 51 36, 46 -0.0107 0.117 0.927 0.033 0.989 0.789 1.24 -0.0218 0.344 0.949 0.023 0.978 0.504 1.89 0.114 0.332 0.732 0.136 1.12 0.592 2.13 -0.169 0.359 0.638 0.195 0.845 0.422 1.68 PRS_PLINK_0.000199526231496888 FALSE 625.1 Dyspareunia Female 28 118 11 genitourinary black 118, 28 29, 3 29, 8 29, 8 30, 9 0.123 0.224 0.583 0.235 1.13 0.736 1.76 0.863 0.736 0.241 0.617 2.37 0.596 11 0.896 0.709 0.207 0.685 2.45 0.653 10.9 0.497 0.742 0.503 0.298 1.64 0.394 7.8 PRS_PLINK_0.000199526231496888 TRUE 626 Disorders of menstruation and other abnormal bleeding from female genital tract Female 252 96 11 genitourinary black 96, 252 24, 51 24, 75 24, 63 24, 62 0.00664 0.128 0.959 0.018 1.01 0.783 1.29 0.467 0.385 0.225 0.647 1.59 0.756 3.42 0.199 0.363 0.583 0.235 1.22 0.606 2.46 0.00382 0.378 0.992 0.004 1 0.482 2.08 PRS_PLINK_0.000199526231496888 FALSE 626.1 Irregular menstrual cycle/bleeding Female 211 93 11 genitourinary black 93, 211 24, 49 23, 61 23, 53 23, 48 -0.0641 0.134 0.632 0.199 0.938 0.722 1.22 0.402 0.398 0.312 0.506 1.49 0.693 3.28 0.0697 0.376 0.853 0.069 1.07 0.519 2.21 -0.255 0.396 0.52 0.284 0.775 0.359 1.65 PRS_PLINK_0.000199526231496888 FALSE 626.11 Absent or infrequent menstruation Female 86 75 11 genitourinary black 75, 86 19, 13 19, 34 18, 19 19, 20 0.139 0.168 0.408 0.39 1.15 0.836 1.59 0.766 0.504 0.128 0.892 2.15 0.842 5.6 0.463 0.562 0.41 0.388 1.59 0.553 4.67 0.248 0.571 0.664 0.178 1.28 0.437 3.78 PRS_PLINK_0.000199526231496888 FALSE 626.12 Excessive or frequent menstruation Female 92 85 11 genitourinary black 85, 92 22, 31 21, 24 21, 18 21, 19 -0.258 0.156 0.0981 1.008 0.773 0.57 1.04 -0.302 0.489 0.538 0.27 0.74 0.286 1.86 -0.383 0.482 0.427 0.37 0.681 0.269 1.69 -0.589 0.483 0.222 0.653 0.555 0.216 1.37 PRS_PLINK_0.000199526231496888 FALSE 626.13 Irregular menstrual cycle Female 107 84 11 genitourinary black 84, 107 21, 22 21, 33 21, 28 21, 24 0.0304 0.164 0.853 0.069 1.03 0.753 1.41 0.473 0.453 0.297 0.528 1.6 0.682 3.83 0.371 0.48 0.44 0.357 1.45 0.587 3.64 -0.342 0.509 0.501 0.3 0.71 0.266 1.83 PRS_PLINK_0.000199526231496888 FALSE 626.14 Irregular menstrual bleeding Female 48 72 11 genitourinary black 72, 48 18, 15 18, 13 18, 9 18, 11 -0.197 0.207 0.34 0.468 0.821 0.551 1.21 -0.159 0.638 0.803 0.095 0.853 0.252 2.79 -0.429 0.606 0.478 0.32 0.651 0.203 1.98 -0.488 0.653 0.455 0.342 0.614 0.173 2 PRS_PLINK_0.000199526231496888 TRUE 626.15 Infertility, female, associated with anovulation Female 53 44 11 genitourinary black 44, 53 11, 10 11, 13 11, 12 11, 18 0.1 0.217 0.645 0.191 1.11 0.737 1.67 0.153 0.71 0.83 0.081 1.17 0.315 4.28 0.552 0.735 0.453 0.344 1.74 0.459 7.09 0.431 0.694 0.534 0.272 1.54 0.427 5.9 PRS_PLINK_0.000199526231496888 FALSE 626.2 Dysmenorrhea Female 65 76 11 genitourinary black 76, 65 19, 14 19, 21 19, 16 19, 14 -0.0256 0.184 0.89 0.051 0.975 0.685 1.38 0.168 0.593 0.777 0.109 1.18 0.372 3.61 0.262 0.555 0.637 0.196 1.3 0.463 3.7 -0.528 0.672 0.432 0.365 0.59 0.152 2.01 PRS_PLINK_0.000199526231496888 FALSE 626.4 Premenstrual tension syndromes Female 16 30 11 genitourinary black 30, 16 8, 2 7, 10 7, 3 8, 1 -0.527 0.478 0.27 0.569 0.59 0.163 1.36 0.86 1.65 0.602 0.221 2.36 0.112 131 -0.68 1.63 0.677 0.17 0.507 0.00217 11.3 -2.17 1.82 0.231 0.636 0.114 0.00114 2.82 PRS_PLINK_0.000199526231496888 TRUE 626.8 Infertility, female Female 89 69 11 genitourinary black 69, 89 18, 16 17, 31 17, 17 17, 24 -0.055 0.172 0.749 0.125 0.947 0.68 1.31 0.437 0.525 0.406 0.392 1.55 0.573 4.18 0.21 0.577 0.716 0.145 1.23 0.417 3.7 0.0527 0.602 0.93 0.031 1.05 0.33 3.35 PRS_PLINK_0.000199526231496888 FALSE 627 Menopausal and postmenopausal disorders Female 91 91 11 genitourinary black 91, 91 23, 21 23, 23 22, 26 23, 21 -0.102 0.167 0.541 0.267 0.903 0.655 1.24 -0.0286 0.471 0.952 0.022 0.972 0.397 2.36 0.174 0.482 0.718 0.144 1.19 0.474 3 -0.113 0.499 0.821 0.085 0.893 0.341 2.28 PRS_PLINK_0.000199526231496888 FALSE 627.1 Postmenopausal bleeding Female 26 41 11 genitourinary black 41, 26 11, 5 10, 8 10, 10 10, 3 -0.195 0.295 0.509 0.294 0.823 0.466 1.4 0.597 0.81 0.461 0.336 1.82 0.439 8.47 0.534 0.761 0.483 0.316 1.71 0.434 6.91 -0.564 1.02 0.58 0.237 0.569 0.076 3.54 PRS_PLINK_0.000199526231496888 TRUE 627.2 Symptomatic menopause Female 53 78 11 genitourinary black 78, 53 20, 12 19, 16 19, 13 20, 12 -0.187 0.203 0.355 0.45 0.829 0.561 1.21 0.177 0.571 0.757 0.121 1.19 0.413 3.46 0.0148 0.598 0.98 0.009 1.01 0.328 3.14 -0.335 0.617 0.587 0.231 0.715 0.215 2.23 PRS_PLINK_0.000199526231496888 FALSE 627.21 Symptomatic artificial menopause Female 3 11 11 genitourinary black 11, 3 3, 2 3, 0 2, 0 3, 1 0.561 1.68 0.738 0.132 1.75 0.0776 377 -0.938 3.2 0.769 0.114 0.391 0.00246 105 -0.328 13500000 1 0 0.72 0.0266 29.3 2.26 3.66 0.536 0.271 9.63 0.0206 482 PRS_PLINK_0.000199526231496888 TRUE 627.22 Need for Hormone replacement therapy (postmenopausal) Female 4 17 11 genitourinary black 17, 4 5, 0 4, 1 4, 0 4, 3 0.0703 0.728 0.923 0.035 1.07 0.273 3.84 1.52 2.12 0.474 0.324 4.56 0.184 576 1.11 3.62 0.759 0.12 3.04 2.67 3.31 PRS_PLINK_0.000199526231496888 TRUE 627.3 Postmenopausal atrophic vaginitis Female 17 37 11 genitourinary black 37, 17 10, 4 9, 3 9, 7 9, 3 -0.275 0.338 0.416 0.381 0.76 0.398 1.4 -0.384 0.988 0.697 0.157 0.681 0.101 3.79 0.724 0.971 0.456 0.341 2.06 0.397 12.9 -0.286 1.17 0.806 0.094 0.752 0.0715 6.81 PRS_PLINK_0.000199526231496888 TRUE 627.4 Premenopausal menorrhagia Female 18 30 11 genitourinary black 30, 18 8, 4 7, 5 7, 4 8, 5 -0.2 0.341 0.558 0.253 0.819 0.42 1.5 0.324 1.16 0.779 0.109 1.38 0.172 10.2 -0.519 1.27 0.682 0.166 0.595 0.0388 5.09 -0.267 1.04 0.798 0.098 0.766 0.104 4.8 PRS_PLINK_0.000199526231496888 TRUE 627.5 Premature menopause and other ovarian failure Female 14 30 11 genitourinary black 30, 14 8, 4 7, 3 7, 1 8, 6 -0.0231 0.317 0.942 0.026 0.977 0.544 1.74 1.2 1.34 0.371 0.431 3.31 0.341 54.1 -0.447 1.38 0.746 0.128 0.64 0.0146 8.58 0.685 1.02 0.501 0.3 1.98 0.347 13.2 PRS_PLINK_0.000199526231496888 TRUE 628 Ovarian cyst Female 73 89 11 genitourinary black 89, 73 23, 15 22, 22 22, 17 22, 19 -0.0351 0.171 0.838 0.077 0.966 0.693 1.34 0.453 0.543 0.404 0.393 1.57 0.563 4.44 0.108 0.526 0.837 0.077 1.11 0.411 3.01 -0.268 0.587 0.648 0.189 0.765 0.239 2.3 PRS_PLINK_0.000199526231496888 FALSE 634 Miscarriage; stillbirth Female 89 92 12 pregnancy complications royalblue4 92, 89 23, 27 23, 27 23, 13 23, 22 -0.248 0.17 0.144 0.841 0.781 0.561 1.08 -0.0096 0.448 0.983 0.007 0.99 0.423 2.31 -0.645 0.497 0.195 0.711 0.525 0.199 1.33 -0.439 0.473 0.353 0.453 0.644 0.26 1.56 PRS_PLINK_0.000199526231496888 FALSE 634.1 Missed abortion/Hydatidiform mole Female 40 35 12 pregnancy complications royalblue4 35, 40 9, 12 9, 15 8, 5 9, 8 -0.308 0.257 0.231 0.637 0.735 0.444 1.18 0.658 0.796 0.409 0.389 1.93 0.446 9.14 -1.74 1.08 0.106 0.975 0.176 0.0169 1.1 -0.557 0.775 0.472 0.326 0.573 0.131 2.31 PRS_PLINK_0.000199526231496888 TRUE 634.3 Ectopic pregnancy Female 8 11 12 pregnancy complications royalblue4 11, 8 3, 5 3, 0 2, 0 3, 3 -0.342 1.01 0.735 0.134 0.711 0.089 3.57 -0.435 4.04 0.914 0.039 0.647 6e-07 7130 -4.14 402 0.992 0.004 0.0159 2.26e-13 51300 -0.908 2 0.649 0.188 0.403 0.00405 18.1 PRS_PLINK_0.000199526231496888 TRUE 635 Hemorrhage during pregnancy; childbirth and postpartum Female 82 74 12 pregnancy complications royalblue4 74, 82 19, 20 18, 35 18, 11 19, 15 -0.246 0.176 0.161 0.793 0.782 0.555 1.09 0.598 0.496 0.227 0.643 1.82 0.708 4.76 -0.601 0.562 0.285 0.545 0.548 0.183 1.55 -0.389 0.524 0.458 0.339 0.678 0.25 1.77 PRS_PLINK_0.000199526231496888 FALSE 635.2 Antepartum hemorrhage, abruptio placentae, and placenta previa Female 56 51 12 pregnancy complications royalblue4 51, 56 13, 17 13, 18 12, 9 13, 11 -0.177 0.21 0.399 0.399 0.838 0.557 1.24 0.0323 0.604 0.957 0.019 1.03 0.321 3.28 -0.186 0.679 0.784 0.106 0.83 0.229 3 -0.391 0.633 0.537 0.27 0.676 0.2 2.15 PRS_PLINK_0.000199526231496888 FALSE 635.3 Placenta previa and abruptio placenta Female 44 44 12 pregnancy complications royalblue4 44, 44 11, 15 11, 13 11, 8 11, 8 -0.175 0.258 0.497 0.304 0.839 0.509 1.36 0.07 0.676 0.918 0.037 1.07 0.302 3.91 -0.45 0.699 0.52 0.284 0.638 0.17 2.29 -0.717 0.768 0.35 0.455 0.488 0.113 1.92 PRS_PLINK_0.000199526231496888 TRUE 636 Early or threatened labor; hemorrhage in early pregnancy Female 150 101 12 pregnancy complications royalblue4 101, 150 26, 29 25, 49 25, 30 25, 42 0.027 0.134 0.841 0.075 1.03 0.794 1.33 0.643 0.407 0.114 0.942 1.9 0.882 4.16 0.146 0.407 0.72 0.143 1.16 0.538 2.51 0.435 0.399 0.276 0.559 1.54 0.73 3.31 PRS_PLINK_0.000199526231496888 FALSE 636.1 Threatened premature labor Female 50 46 12 pregnancy complications royalblue4 46, 50 12, 12 11, 17 11, 9 12, 12 -0.0678 0.259 0.793 0.101 0.934 0.571 1.52 0.533 0.63 0.398 0.401 1.7 0.557 5.52 0.452 0.842 0.591 0.228 1.57 0.352 7.88 -0.261 0.753 0.729 0.137 0.77 0.191 3.09 PRS_PLINK_0.000199526231496888 TRUE 636.2 Early onset of delivery Female 37 34 12 pregnancy complications royalblue4 34, 37 9, 8 8, 11 8, 8 9, 10 0.0339 0.25 0.892 0.05 1.03 0.65 1.66 0.704 0.794 0.376 0.425 2.02 0.502 9.01 0.281 0.837 0.737 0.132 1.32 0.3 6.08 0.429 0.79 0.587 0.231 1.54 0.374 7.1 PRS_PLINK_0.000199526231496888 TRUE 636.3 Hemorrhage in early pregnancy Female 64 59 12 pregnancy complications royalblue4 59, 64 15, 18 15, 22 14, 10 15, 14 -0.266 0.215 0.216 0.666 0.767 0.505 1.14 0.0925 0.537 0.863 0.064 1.1 0.402 2.98 -0.709 0.639 0.267 0.573 0.492 0.145 1.56 -0.0924 0.592 0.876 0.057 0.912 0.303 2.78 PRS_PLINK_0.000199526231496888 FALSE 636.8 Cervical incompetence Female 9 9 12 pregnancy complications royalblue4 9, 9 3, 4 2, 2 2, 1 2, 2 -0.443 1.46 0.762 0.118 0.642 0.017 1160 -0.87 15.8 0.956 0.019 0.419 0.39 0.46 -0.543 2.6 0.835 0.078 0.581 0.538 0.687 0.43 3.21 0.894 0.049 1.54 1.07 1.71 PRS_PLINK_0.000199526231496888 TRUE 637 Short gestation; low birth weight; and fetal growth retardation Both 4 6 12 pregnancy complications royalblue4 6, 4 2, 0 1, 2 1, 0 2, 2 -0.188 2.71 0.945 0.025 0.828 0.777 1.93 -0.0591 111 1 0 0.943 0.58 3.4 -0.0538 448 1 0 0.948 0.455 1.58 PRS_PLINK_0.000199526231496888 TRUE 642 Hypertension complicating pregnancy, childbirth, and the puerperium Female 86 127 12 pregnancy complications royalblue4 127, 86 32, 25 32, 18 31, 18 32, 24 -0.0837 0.154 0.586 0.232 0.92 0.682 1.24 -0.22 0.436 0.613 0.213 0.802 0.347 1.84 -0.449 0.429 0.296 0.529 0.638 0.278 1.44 -0.119 0.421 0.778 0.109 0.888 0.398 1.97 PRS_PLINK_0.000199526231496888 FALSE 642.1 Preeclampsia and eclampsia Female 38 69 12 pregnancy complications royalblue4 69, 38 18, 11 17, 11 17, 9 17, 7 -0.109 0.217 0.617 0.209 0.897 0.595 1.35 0.233 0.676 0.731 0.136 1.26 0.355 4.55 0.198 0.629 0.753 0.123 1.22 0.387 4 -0.152 0.63 0.81 0.092 0.859 0.267 2.73 PRS_PLINK_0.000199526231496888 TRUE 643 Excessive vomiting in pregnancy Female 36 78 12 pregnancy complications royalblue4 78, 36 20, 6 19, 7 19, 13 20, 9 0.103 0.218 0.637 0.196 1.11 0.737 1.69 -0.227 0.702 0.746 0.127 0.797 0.202 2.94 0.764 0.622 0.219 0.659 2.15 0.693 7.26 0.174 0.731 0.812 0.091 1.19 0.297 4.82 PRS_PLINK_0.000199526231496888 TRUE 643.1 Hyperemesis gravidarum Female 16 34 12 pregnancy complications royalblue4 34, 16 9, 3 8, 5 8, 3 9, 5 0.16 0.349 0.646 0.19 1.17 0.621 2.28 -0.257 1.14 0.823 0.085 0.774 0.071 5.65 0.336 0.993 0.735 0.133 1.4 0.254 8.1 0.463 0.95 0.626 0.203 1.59 0.304 9.39 PRS_PLINK_0.000199526231496888 TRUE 644 Anemia during pregnancy Female 32 83 12 pregnancy complications royalblue4 83, 32 20, 10 21, 6 20, 7 21, 9 -0.16 0.22 0.467 0.33 0.852 0.56 1.29 -0.58 0.635 0.361 0.443 0.56 0.158 1.8 -0.397 0.627 0.526 0.279 0.672 0.206 2.13 -0.342 0.649 0.598 0.223 0.71 0.205 2.34 PRS_PLINK_0.000199526231496888 TRUE 646 Other complications of pregnancy NEC Female 135 129 12 pregnancy complications royalblue4 129, 135 33, 37 32, 33 32, 37 32, 27 -0.18 0.133 0.175 0.756 0.835 0.645 1.08 -0.0506 0.362 0.889 0.051 0.951 0.477 1.9 -0.114 0.357 0.75 0.125 0.893 0.451 1.76 -0.373 0.399 0.349 0.457 0.689 0.32 1.47 PRS_PLINK_0.000199526231496888 FALSE 647 Infectious and parasitic complications affecting pregnancy Female 20 65 12 pregnancy complications royalblue4 65, 20 16, 4 16, 5 16, 4 16, 7 0.257 0.278 0.356 0.449 1.29 0.774 2.28 1.45 1.15 0.207 0.684 4.27 0.551 81.3 0.259 0.837 0.757 0.121 1.3 0.273 6.72 0.878 0.952 0.357 0.448 2.41 0.426 16.1 PRS_PLINK_0.000199526231496888 TRUE 647.1 Infections of genitourinary tract during pregnancy Female 38 57 12 pregnancy complications royalblue4 57, 38 14, 10 14, 12 14, 7 14, 9 0.0466 0.23 0.839 0.076 1.05 0.681 1.62 -0.19 0.635 0.765 0.116 0.827 0.252 2.67 -0.257 0.683 0.707 0.151 0.774 0.218 2.67 -0.217 0.68 0.75 0.125 0.805 0.227 2.77 PRS_PLINK_0.000199526231496888 TRUE 647.3 Major puerperal infection Female 14 21 12 pregnancy complications royalblue4 21, 14 5, 3 5, 3 5, 7 5, 1 -0.185 0.38 0.627 0.203 0.831 0.412 1.62 -1.26 1.6 0.433 0.364 0.285 0.00192 3.21 0.208 1.44 0.885 0.053 1.23 0.0219 25.3 -1.79 1.74 0.302 0.52 0.166 0.000831 2.26 PRS_PLINK_0.000199526231496888 TRUE 649 Other conditions or status of the mother complicating pregnancy, childbirth, or the puerperium Female 186 85 12 pregnancy complications royalblue4 85, 186 22, 37 21, 47 21, 48 21, 53 0.104 0.134 0.438 0.359 1.11 0.857 1.44 0.165 0.413 0.69 0.161 1.18 0.535 2.6 0.266 0.427 0.534 0.273 1.3 0.572 3 0.377 0.403 0.349 0.457 1.46 0.677 3.18 PRS_PLINK_0.000199526231496888 FALSE 649.1 Diabetes or abnormal glucose tolerance complicating pregnancy Female 131 51 12 pregnancy complications royalblue4 51, 131 13, 24 13, 34 12, 34 13, 38 0.11 0.168 0.513 0.29 1.12 0.81 1.54 0.478 0.509 0.348 0.458 1.61 0.625 4.24 0.501 0.544 0.358 0.446 1.65 0.595 4.73 0.324 0.513 0.527 0.278 1.38 0.52 3.71 PRS_PLINK_0.000199526231496888 FALSE 653 Problems associated with amniotic cavity and membranes Female 104 105 12 pregnancy complications royalblue4 105, 104 27, 22 26, 22 26, 22 26, 38 0.202 0.155 0.192 0.716 1.22 0.912 1.65 0.0689 0.452 0.879 0.056 1.07 0.455 2.5 -0.195 0.437 0.656 0.183 0.823 0.357 1.87 0.876 0.434 0.0437 1.359 2.4 1.07 5.61 PRS_PLINK_0.000199526231496888 FALSE 654.1 Abnormality of organs and soft tissues of pelvis complicating pregnancy, childbirth, or the puerperium Female 41 45 12 pregnancy complications royalblue4 45, 41 12, 10 11, 10 11, 7 11, 13 -0.0696 0.226 0.758 0.12 0.933 0.607 1.42 0.0558 0.687 0.935 0.029 1.06 0.296 3.69 -0.131 0.825 0.874 0.059 0.877 0.183 4.27 0.471 0.715 0.51 0.292 1.6 0.44 6.21 PRS_PLINK_0.000199526231496888 TRUE 654.2 Rhesus isoimmunization in pregnancy Female 33 27 12 pregnancy complications royalblue4 27, 33 7, 9 7, 7 6, 8 7, 9 0.0361 0.303 0.905 0.043 1.04 0.595 1.82 -0.0235 1.16 0.984 0.007 0.977 0.13 8.52 0.34 1.07 0.75 0.125 1.4 0.206 11.1 -0.0959 0.851 0.91 0.041 0.909 0.201 4.02 PRS_PLINK_0.000199526231496888 TRUE 655 Known or suspected fetal abnormality affecting management of mother Female 219 96 12 pregnancy complications royalblue4 96, 219 24, 52 24, 62 24, 52 24, 52 -0.095 0.128 0.457 0.34 0.909 0.708 1.16 0.0912 0.36 0.8 0.097 1.1 0.546 2.19 -0.015 0.367 0.968 0.014 0.985 0.486 1.99 -0.148 0.37 0.689 0.162 0.862 0.421 1.75 PRS_PLINK_0.000199526231496888 FALSE 655.1 Abnormality in fetal heart rate or rhythm Female 108 57 12 pregnancy complications royalblue4 57, 108 15, 19 14, 47 14, 17 14, 24 -0.0951 0.171 0.579 0.238 0.909 0.652 1.26 0.937 0.535 0.0797 1.098 2.55 0.94 7.25 0.125 0.589 0.832 0.08 1.13 0.381 3.46 0.403 0.587 0.492 0.308 1.5 0.508 4.72 PRS_PLINK_0.000199526231496888 FALSE 656 Other perinatal conditions of fetus or newborn Both 135 111 12 pregnancy complications royalblue4 111, 135 27, 34 28, 41 27, 31 28, 29 -0.0169 0.132 0.898 0.047 0.983 0.762 1.27 0.247 0.374 0.51 0.292 1.28 0.63 2.62 -0.0394 0.388 0.919 0.037 0.961 0.46 2.01 -0.129 0.4 0.748 0.126 0.879 0.413 1.88 PRS_PLINK_0.000199526231496888 FALSE 656.2 Respiratory conditions of fetus and newborn Both 2 5 12 pregnancy complications royalblue4 5, 2 2, 0 1, 0 1, 1 1, 1 -0.168 486000 1 0 0.845 0.631 1.27 -0.826 498 0.999 0.001 0.438 0.00285 147 -0.00181 7650 1 0 0.998 0.157 6.33 PRS_PLINK_0.000199526231496888 TRUE 669 Complications of labor and delivery NEC Female 137 122 12 pregnancy complications royalblue4 122, 137 31, 31 30, 37 30, 27 31, 41 0.0358 0.129 0.782 0.107 1.04 0.808 1.33 0.162 0.379 0.669 0.175 1.18 0.573 2.42 -0.224 0.388 0.564 0.249 0.8 0.381 1.67 0.22 0.372 0.554 0.256 1.25 0.615 2.54 PRS_PLINK_0.000199526231496888 FALSE 671 Venous/cerebrovascular complications embolism in pregnancy and the puerperium Female 18 52 12 pregnancy complications royalblue4 52, 18 13, 6 13, 1 13, 5 13, 6 -0.223 0.312 0.476 0.323 0.8 0.432 1.41 -1.76 1.41 0.213 0.672 0.173 0.00141 2.01 -0.159 0.926 0.864 0.064 0.853 0.145 4.5 -0.663 0.929 0.475 0.323 0.515 0.071 2.59 PRS_PLINK_0.000199526231496888 TRUE 674 Other complications of the puerperium NEC Female 31 36 12 pregnancy complications royalblue4 36, 31 9, 3 9, 7 9, 7 9, 14 0.658 0.328 0.0452 1.345 1.93 1.09 3.67 0.804 1.14 0.48 0.319 2.23 0.296 20.6 0.585 0.9 0.515 0.288 1.8 0.387 9.97 0.944 0.819 0.249 0.604 2.57 0.631 12 PRS_PLINK_0.000199526231496888 TRUE 676 Other disorders of the breast associated with childbirth and disorders of lactation Female 40 47 12 pregnancy complications royalblue4 47, 40 12, 6 12, 6 11, 16 12, 11 0.207 0.267 0.439 0.358 1.23 0.756 2.07 0.81 1.02 0.426 0.37 2.25 0.353 17.9 1.13 0.74 0.125 0.903 3.11 0.847 14.1 0.537 0.855 0.53 0.276 1.71 0.374 10.1 PRS_PLINK_0.000199526231496888 TRUE 681 Superficial cellulitis and abscess Both 115 308 13 dermatologic firebrick 308, 115 76, 40 77, 24 77, 25 77, 26 -0.156 0.116 0.178 0.75 0.855 0.682 1.07 -0.529 0.319 0.0971 1.013 0.589 0.316 1.08 -0.531 0.318 0.0946 1.024 0.588 0.316 1.08 -0.361 0.318 0.256 0.591 0.697 0.375 1.28 PRS_PLINK_0.000199526231496888 FALSE 681.1 Cellulitis and abscess of fingers/toes Both 30 78 13 dermatologic firebrick 78, 30 20, 10 19, 9 19, 4 20, 7 0.00261 0.226 0.991 0.004 1 0.65 1.55 0.0883 0.612 0.885 0.053 1.09 0.351 3.44 -0.436 0.703 0.535 0.272 0.646 0.167 2.32 -0.075 0.671 0.911 0.04 0.928 0.256 3.25 PRS_PLINK_0.000199526231496888 TRUE 681.2 Cellulitis and abscess of face/neck Both 19 62 13 dermatologic firebrick 62, 19 16, 7 15, 4 15, 6 16, 2 -0.299 0.298 0.316 0.501 0.742 0.41 1.29 -0.239 0.757 0.752 0.124 0.787 0.184 3.17 -0.231 0.702 0.743 0.129 0.794 0.21 2.86 -0.862 0.852 0.312 0.506 0.422 0.059 1.92 PRS_PLINK_0.000199526231496888 TRUE 681.3 Cellulitis and abscess of arm/hand Both 36 141 13 dermatologic firebrick 141, 36 36, 15 35, 4 35, 7 35, 10 -0.128 0.185 0.488 0.311 0.88 0.611 1.26 -1.1 0.618 0.0757 1.121 0.334 0.0892 1.04 -0.744 0.52 0.152 0.817 0.475 0.167 1.24 -0.2 0.503 0.692 0.16 0.819 0.308 2.14 PRS_PLINK_0.000199526231496888 TRUE 681.5 Cellulitis and abscess of leg, except foot Both 39 143 13 dermatologic firebrick 143, 39 36, 16 36, 3 35, 7 36, 13 0.00523 0.176 0.976 0.01 1.01 0.713 1.42 -1.69 0.668 0.0116 1.936 0.185 0.0411 0.619 -0.831 0.533 0.119 0.924 0.436 0.147 1.17 -0.145 0.464 0.755 0.122 0.865 0.354 2.09 PRS_PLINK_0.000199526231496888 TRUE 681.6 Cellulitis and abscess of foot, toe Both 30 118 13 dermatologic firebrick 118, 30 30, 12 29, 3 29, 7 30, 8 -0.0173 0.201 0.932 0.031 0.983 0.664 1.45 -1.38 0.747 0.0646 1.19 0.251 0.0482 0.975 -0.423 0.546 0.438 0.359 0.655 0.226 1.81 -0.199 0.556 0.72 0.142 0.82 0.279 2.36 PRS_PLINK_0.000199526231496888 TRUE 681.7 Cellulitis and abscess of trunk Both 29 126 13 dermatologic firebrick 126, 29 31, 7 31, 10 31, 9 32, 3 -0.163 0.237 0.49 0.31 0.849 0.534 1.35 0.43 0.594 0.469 0.328 1.54 0.502 5.12 0.0648 0.667 0.923 0.035 1.07 0.29 3.91 -0.808 0.702 0.249 0.603 0.446 0.0987 1.66 PRS_PLINK_0.000199526231496888 TRUE 686 Other local infections of skin and subcutaneous tissue Both 32 158 13 dermatologic firebrick 158, 32 40, 7 39, 4 39, 11 40, 10 0.0753 0.195 0.699 0.156 1.08 0.739 1.59 -0.13 0.665 0.845 0.073 0.878 0.225 3.33 0.313 0.559 0.576 0.24 1.37 0.465 4.16 0.599 0.563 0.287 0.542 1.82 0.628 5.63 PRS_PLINK_0.000199526231496888 TRUE 686.1 Carbuncle and furuncle Both 13 59 13 dermatologic firebrick 59, 13 15, 5 15, 4 14, 3 15, 1 -0.676 0.441 0.125 0.902 0.509 0.202 1.16 -0.469 1.12 0.675 0.171 0.626 0.0699 4.64 -1.51 1.13 0.179 0.748 0.22 0.0158 1.49 -2.28 1.67 0.173 0.761 0.102 6.41e-06 1.61 PRS_PLINK_0.000199526231496888 TRUE 686.2 Impetigo Both 10 43 13 dermatologic firebrick 43, 10 10, 3 11, 0 10, 4 11, 3 0.214 0.379 0.573 0.242 1.24 0.607 2.83 -1.32 1.38 0.34 0.469 0.267 0.000661 2.74 0.178 1.06 0.866 0.062 1.19 0.174 8.37 -1.23 1.35 0.359 0.444 0.291 0.00129 2.96 PRS_PLINK_0.000199526231496888 TRUE 686.3 Pilonidal cyst Both 3 19 13 dermatologic firebrick 19, 3 4, 1 5, 1 4, 1 5, 0 -0.675 1.03 0.513 0.29 0.509 4.07e-06 3.6 1.52 2.82 0.591 0.229 4.57 0.134 5.21 -0.603 2.71 0.824 0.084 0.547 0.00194 75.4 1.26 3.87 0.745 0.128 3.53 0.0136 2630 PRS_PLINK_0.000199526231496888 TRUE 686.4 Pyogenic granuloma Both 1 22 13 dermatologic firebrick 22, 1 5, 1 5, 0 5, 0 6, 0 -0.343 0.684 0.616 0.21 0.71 0.102 7.53 -0.741 2.08 0.722 0.141 0.476 0.00214 21.8 -0.471 2.46 0.848 0.071 0.625 0.000469 47.9 -1.1 2.49 0.658 0.182 0.331 9.24e-05 25.1 PRS_PLINK_0.000199526231496888 TRUE 686.5 Pyoderma Both 0 8 13 dermatologic firebrick 8, 0 2 2 2 2 PRS_PLINK_0.000199526231496888 TRUE 687 Symptoms affecting skin Both 29 109 13 dermatologic firebrick 109, 29 27, 7 27, 9 27, 6 27, 7 0.0708 0.216 0.743 0.129 1.07 0.71 1.64 0.251 0.628 0.689 0.162 1.29 0.388 4.55 0.117 0.678 0.863 0.064 1.12 0.299 4.27 0.267 0.661 0.687 0.163 1.31 0.36 5.19 PRS_PLINK_0.000199526231496888 TRUE 687.1 Rash and other nonspecific skin eruption Both 140 233 13 dermatologic firebrick 233, 140 58, 38 58, 39 58, 28 58, 35 -0.085 0.117 0.469 0.329 0.919 0.732 1.15 0.0835 0.312 0.789 0.103 1.09 0.598 1.98 -0.469 0.342 0.17 0.769 0.626 0.322 1.2 -0.343 0.331 0.301 0.522 0.71 0.374 1.33 PRS_PLINK_0.000199526231496888 FALSE 687.3 Changes in skin texture Both 7 23 13 dermatologic firebrick 23, 7 6, 1 6, 4 5, 0 6, 2 0.034 0.501 0.946 0.024 1.03 0.415 2.66 1.37 1.78 0.443 0.354 3.92 0.193 213 0.437 3.17 0.89 0.05 1.55 0.00525 2280 1.12 1.83 0.541 0.267 3.05 0.146 234 PRS_PLINK_0.000199526231496888 TRUE 687.4 Disturbance of skin sensation Both 129 233 13 dermatologic firebrick 233, 129 58, 37 58, 37 58, 26 58, 29 -0.0909 0.118 0.441 0.355 0.913 0.726 1.15 0.0291 0.338 0.931 0.031 1.03 0.538 1.97 -0.332 0.339 0.327 0.486 0.717 0.372 1.37 -0.357 0.342 0.297 0.527 0.7 0.361 1.34 PRS_PLINK_0.000199526231496888 FALSE 689 Disorder of skin and subcutaneous tissue NOS Both 143 310 13 dermatologic firebrick 310, 143 77, 32 77, 41 77, 32 78, 38 -0.0277 0.109 0.799 0.097 0.973 0.787 1.2 0.303 0.321 0.344 0.464 1.35 0.732 2.53 0.0233 0.329 0.943 0.025 1.02 0.543 1.93 0.0754 0.326 0.817 0.088 1.08 0.576 2.03 PRS_PLINK_0.000199526231496888 FALSE 690 Erythematosquamous dermatosis Both 75 238 13 dermatologic firebrick 238, 75 59, 16 59, 19 59, 11 60, 29 0.261 0.148 0.0781 1.107 1.3 0.977 1.74 0.482 0.474 0.309 0.511 1.62 0.651 4.22 -0.563 0.513 0.273 0.565 0.569 0.203 1.52 0.739 0.419 0.0775 1.111 2.09 0.949 4.83 PRS_PLINK_0.000199526231496888 FALSE 690.1 Seborrheic dermatitis Both 75 238 13 dermatologic firebrick 238, 75 59, 16 59, 19 59, 11 60, 29 0.261 0.148 0.0781 1.107 1.3 0.977 1.74 0.482 0.474 0.309 0.511 1.62 0.651 4.22 -0.563 0.513 0.273 0.565 0.569 0.203 1.52 0.739 0.419 0.0775 1.111 2.09 0.949 4.83 PRS_PLINK_0.000199526231496888 FALSE 691 Congenital anomalies of skin Both 13 49 13 dermatologic firebrick 49, 13 12, 3 12, 4 12, 3 12, 3 0.0351 0.333 0.916 0.038 1.04 0.56 1.99 0.319 0.9 0.723 0.141 1.38 0.27 7.66 0.081 0.982 0.934 0.03 1.08 0.164 6.97 0.628 1.15 0.585 0.233 1.87 0.235 21.9 PRS_PLINK_0.000199526231496888 TRUE 691.3 Congenital pigmentary anomalies of skin Both 2 5 13 dermatologic firebrick 5, 2 1, 0 1, 0 1, 1 1, 1 -0.0238 539 1 0 0.977 0.594 3.85 0.0523 178 1 0 1.05 0.72 2.3 -0.0461 5000 1 0 0.955 0.383 1.53 PRS_PLINK_0.000199526231496888 TRUE 694 Dyschromia and Vitiligo Both 37 131 13 dermatologic firebrick 131, 37 32, 5 33, 14 32, 2 33, 16 0.407 0.221 0.0653 1.185 1.5 0.987 2.35 0.931 0.595 0.118 0.928 2.54 0.837 8.57 -0.176 0.85 0.836 0.078 0.839 0.13 5.45 1.12 0.631 0.0762 1.118 3.06 0.95 11.5 PRS_PLINK_0.000199526231496888 TRUE 694.1 Vitiligo Both 2 13 13 dermatologic firebrick 13, 2 4, 1 3, 0 3, 1 3, 0 0.145 1.07 0.892 0.05 1.16 0.197 7.81 -0.631 174 0.997 0.001 0.532 0.0329 8.64 0.123 2.26 0.957 0.019 1.13 1.11 1.18 -2.01e-11 49.4 1 0 1 0.0215 46.1 PRS_PLINK_0.000199526231496888 TRUE 694.2 Other dyschromia Both 33 118 13 dermatologic firebrick 118, 33 29, 4 29, 12 29, 1 30, 16 0.483 0.24 0.0442 1.355 1.62 1.03 2.64 1.02 0.687 0.139 0.858 2.76 0.752 11.6 -0.629 0.966 0.515 0.288 0.533 0.0494 4.06 1.16 0.662 0.08 1.097 3.19 0.942 12.8 PRS_PLINK_0.000199526231496888 TRUE 694.3 Vascular disorders of skin Both 3 4 13 dermatologic firebrick 4, 3 1, 0 1, 0 1, 1 1, 2 1.55 1090000 1 0 4.72 0.592 41.5 0.315 6430 1 0 1.37 0.526 2.26 0.204 72900 1 0 1.23 0.484 1.99 PRS_PLINK_0.000199526231496888 TRUE 695 Erythematous conditions Both 66 282 13 dermatologic firebrick 282, 66 70, 10 70, 21 70, 11 71, 24 0.185 0.149 0.214 0.67 1.2 0.903 1.61 0.657 0.47 0.162 0.791 1.93 0.786 5.02 0.0876 0.468 0.852 0.07 1.09 0.43 2.82 0.637 0.422 0.131 0.884 1.89 0.848 4.43 PRS_PLINK_0.000199526231496888 FALSE 695.1 Toxic erythema Both 0 9 13 dermatologic firebrick 9, 0 3 2 2 2 PRS_PLINK_0.000199526231496888 TRUE 695.2 Bullous dermatoses Both 1 2 13 dermatologic firebrick 2, 1 1, 1 1, 0 1, 1 1, 0 0.0117 54.6 1 0 1.01 0.901 1.17 -0.0212 139 1 0 0.979 0.709 1.21 PRS_PLINK_0.000199526231496888 TRUE 695.3 Rosacea Both 38 155 13 dermatologic firebrick 155, 38 38, 6 39, 12 38, 6 39, 14 0.282 0.206 0.17 0.769 1.33 0.893 2.01 0.869 0.651 0.182 0.741 2.38 0.691 9.59 0.145 0.642 0.821 0.086 1.16 0.318 4.26 0.765 0.57 0.179 0.746 2.15 0.736 6.81 PRS_PLINK_0.000199526231496888 TRUE 695.4 Lupus (localized and systemic) Both 9 61 13 dermatologic firebrick 61, 9 16, 0 15, 5 15, 0 15, 4 0.628 0.514 0.222 0.654 1.87 0.675 8.34 0.99 1.39 0.476 0.322 2.69 0.119 172 2.45 1.6 0.125 0.903 11.6 0.649 1030 PRS_PLINK_0.000199526231496888 TRUE 695.41 Cutaneous lupus erythematosus Both 5 28 13 dermatologic firebrick 28, 5 7, 0 7, 3 7, 1 7, 1 0.165 0.699 0.813 0.09 1.18 0.268 5.54 0.0272 1.98 0.989 0.005 1.03 0.000513 788 0.356 2.39 0.882 0.055 1.43 0.00131 223 0.279 2.77 0.92 0.036 1.32 0.000225 13200 PRS_PLINK_0.000199526231496888 TRUE 695.42 Systemic lupus erythematosus Both 7 57 13 dermatologic firebrick 57, 7 15, 0 14, 2 14, 1 14, 4 0.78 0.565 0.168 0.776 2.18 0.72 13.1 0.263 1.53 0.864 0.064 1.3 0.00182 111 0.33 1.49 0.824 0.084 1.39 0.0202 475 1.73 1.61 0.283 0.549 5.66 0.207 563 PRS_PLINK_0.000199526231496888 TRUE 695.7 Prurigo and Lichen Both 7 50 13 dermatologic firebrick 50, 7 12, 0 12, 5 12, 1 13, 1 -0.123 0.397 0.756 0.122 0.884 0.395 1.88 3.62 2.05 0.0771 1.113 37.3 1.26 30500 0.848 1.9 0.656 0.183 2.33 0.0587 651 0.25 1.77 0.887 0.052 1.28 0.0161 707 PRS_PLINK_0.000199526231496888 TRUE 695.8 Other specified erythematous conditions Both 10 73 13 dermatologic firebrick 73, 10 19, 2 18, 3 18, 2 18, 3 0.145 0.351 0.68 0.168 1.16 0.575 2.35 0.203 1.1 0.853 0.069 1.23 0.0466 37 -0.644 1.11 0.562 0.25 0.525 0.0433 4.98 0.585 0.857 0.495 0.306 1.8 0.346 12.7 PRS_PLINK_0.000199526231496888 TRUE 695.81 Erythema nodosum Both 2 9 13 dermatologic firebrick 9, 2 3, 0 2, 0 2, 0 2, 2 -0.666 2.91 0.819 0.087 0.514 0.487 0.546 0.201 241 0.999 0 1.22 0.699 1.51 PRS_PLINK_0.000199526231496888 TRUE 695.9 Unspecified erythematous condition Both 11 49 13 dermatologic firebrick 49, 11 13, 5 12, 1 12, 1 12, 4 -0.17 0.32 0.594 0.226 0.844 0.459 1.55 -0.499 1.29 0.699 0.155 0.607 0.0334 11 -1.3 1.12 0.246 0.609 0.272 0.0225 1.93 -0.137 0.929 0.883 0.054 0.872 0.153 5.03 PRS_PLINK_0.000199526231496888 TRUE 696 Psoriasis and related disorders Both 25 116 13 dermatologic firebrick 116, 25 29, 11 29, 2 29, 2 29, 10 0.0834 0.244 0.732 0.135 1.09 0.674 1.75 -1.07 0.781 0.172 0.765 0.344 0.0614 1.46 -1.33 0.816 0.104 0.985 0.265 0.0461 1.18 -0.0629 0.589 0.915 0.039 0.939 0.302 2.93 PRS_PLINK_0.000199526231496888 TRUE 696.3 Pityriasis Both 4 9 13 dermatologic firebrick 9, 4 3, 1 2, 1 2, 0 2, 2 0.113 1.22 0.927 0.033 1.12 0.112 9.6 -0.111 118 0.999 0 0.895 0.000363 1870 -1.67 65.7 0.98 0.009 0.188 0.183 0.193 1.79 3.56 0.615 0.211 6 0.151 7.46 PRS_PLINK_0.000199526231496888 TRUE 696.4 Psoriasis Both 21 111 13 dermatologic firebrick 111, 21 28, 10 28, 1 27, 2 28, 8 0.082 0.261 0.753 0.123 1.09 0.647 1.81 -1.56 0.955 0.102 0.99 0.21 0.0189 1.19 -1.05 0.856 0.219 0.66 0.349 0.0588 1.73 -0.0295 0.676 0.965 0.015 0.971 0.258 3.69 PRS_PLINK_0.000199526231496888 TRUE 696.41 Psoriasis vulgaris Both 20 96 13 dermatologic firebrick 96, 20 24, 10 24, 1 24, 2 24, 7 0.038 0.266 0.887 0.052 1.04 0.614 1.74 -1.47 1.04 0.158 0.802 0.229 0.0192 1.61 -1.15 0.819 0.16 0.796 0.317 0.0574 1.4 -0.194 0.711 0.786 0.105 0.824 0.201 3.3 PRS_PLINK_0.000199526231496888 TRUE 696.42 Psoriatic arthropathy Both 5 25 13 dermatologic firebrick 25, 5 7, 2 6, 0 6, 0 6, 3 1.41 0.873 0.106 0.975 4.1 0.879 165 -0.348 2.27 0.878 0.057 0.706 0.000564 34.7 -0.138 2.15 0.949 0.023 0.871 0.00599 47.5 3.76 2.56 0.141 0.85 43 0.776 3730000 PRS_PLINK_0.000199526231496888 TRUE 697 Sarcoidosis Both 2 20 13 dermatologic firebrick 20, 2 5, 1 5, 0 5, 1 5, 0 -0.879 0.796 0.269 0.57 0.415 0.0375 1.98 -0.249 3.29 0.94 0.027 0.78 0.0146 261 -1.27 2.24 0.571 0.244 0.28 0.0014 16.5 -0.482 2.62 0.854 0.069 0.618 0.00982 77.8 PRS_PLINK_0.000199526231496888 TRUE 698 Pruritus and related conditions Both 56 255 13 dermatologic firebrick 255, 56 63, 12 64, 12 63, 13 64, 19 0.149 0.152 0.327 0.486 1.16 0.864 1.57 -0.128 0.457 0.78 0.108 0.88 0.356 2.16 -0.00153 0.435 0.997 0.001 0.998 0.425 2.35 0.243 0.441 0.582 0.235 1.27 0.539 3.07 PRS_PLINK_0.000199526231496888 FALSE 700 Corns and callosities Both 18 68 13 dermatologic firebrick 68, 18 17, 11 17, 3 17, 1 17, 3 -0.389 0.309 0.208 0.683 0.678 0.366 1.22 -1.05 0.826 0.205 0.689 0.351 0.0657 1.57 -1.42 1.08 0.189 0.724 0.241 0.0138 1.67 -1.44 0.862 0.0941 1.026 0.236 0.0325 1.08 PRS_PLINK_0.000199526231496888 TRUE 701 Other hypertrophic and atrophic conditions of skin Both 133 312 13 dermatologic firebrick 312, 133 77, 36 78, 31 78, 28 78, 38 -0.0728 0.109 0.503 0.298 0.93 0.753 1.15 -0.13 0.307 0.673 0.172 0.878 0.484 1.59 -0.39 0.315 0.215 0.667 0.677 0.366 1.24 0.0582 0.299 0.846 0.073 1.06 0.596 1.89 PRS_PLINK_0.000199526231496888 FALSE 701.1 Keratoderma, acquired Both 13 35 13 dermatologic firebrick 35, 13 9, 5 9, 0 8, 3 9, 5 -0.11 0.447 0.806 0.094 0.896 0.371 2.02 -2.27 1.52 0.135 0.87 0.103 0.000733 1.17 -0.235 1.03 0.82 0.086 0.791 0.129 4.2 0.121 1.1 0.912 0.04 1.13 0.169 13.9 PRS_PLINK_0.000199526231496888 TRUE 701.2 Scar conditions and fibrosis of skin Both 28 170 13 dermatologic firebrick 170, 28 42, 7 42, 9 42, 5 43, 7 -0.0439 0.215 0.838 0.077 0.957 0.63 1.46 0.449 0.57 0.43 0.366 1.57 0.522 5.03 -0.262 0.643 0.683 0.165 0.769 0.199 2.8 -0.00652 0.569 0.991 0.004 0.993 0.316 3.08 PRS_PLINK_0.000199526231496888 TRUE 701.3 Circumscribed scleroderma Both 8 49 13 dermatologic firebrick 49, 8 13, 2 12, 4 12, 2 12, 0 -0.272 0.4 0.497 0.303 0.762 0.329 1.73 1.14 1.31 0.383 0.417 3.13 0.324 82.5 0.676 1.18 0.567 0.246 1.97 0.199 30.9 -0.32 1.49 0.83 0.081 0.726 0.00191 46 PRS_PLINK_0.000199526231496888 TRUE 701.4 Keloid scar Both 7 53 13 dermatologic firebrick 53, 7 13, 2 13, 0 13, 2 13, 3 0.303 0.424 0.475 0.324 1.35 0.592 3.67 -1.2 1.32 0.364 0.439 0.301 0.00588 24.6 -0.589 1.12 0.598 0.223 0.555 0.052 4.44 0.0323 0.99 0.974 0.011 1.03 0.147 6.93 PRS_PLINK_0.000199526231496888 TRUE 701.5 Abnormal granulation tissue Both 5 36 13 dermatologic firebrick 36, 5 9, 1 9, 1 9, 2 9, 1 0.0589 0.531 0.912 0.04 1.06 0.379 3.47 -0.657 1.59 0.679 0.168 0.519 0.0201 9.97 1.61 1.73 0.349 0.457 5.02 0.257 24300 -0.584 1.37 0.669 0.175 0.557 2.4e-05 5.91 PRS_PLINK_0.000199526231496888 TRUE 702 Degenerative skin conditions and other dermatoses Both 94 201 13 dermatologic firebrick 201, 94 50, 22 50, 24 50, 21 50, 27 0.0928 0.144 0.52 0.284 1.1 0.831 1.46 0.331 0.431 0.443 0.354 1.39 0.606 3.27 -0.107 0.426 0.802 0.096 0.899 0.395 2.03 0.516 0.436 0.236 0.627 1.68 0.731 3.98 PRS_PLINK_0.000199526231496888 FALSE 702.1 Actinic keratosis Both 44 130 13 dermatologic firebrick 130, 44 33, 12 32, 11 32, 10 33, 11 0.108 0.199 0.588 0.231 1.11 0.761 1.65 -0.00947 0.54 0.986 0.006 0.991 0.349 2.8 -0.0808 0.567 0.887 0.052 0.922 0.306 2.72 0.0302 0.567 0.958 0.019 1.03 0.345 3.08 PRS_PLINK_0.000199526231496888 TRUE 702.2 Seborrheic keratosis Both 80 224 13 dermatologic firebrick 224, 80 55, 17 56, 20 56, 16 56, 27 0.246 0.144 0.0892 1.05 1.28 0.969 1.7 0.284 0.427 0.506 0.296 1.33 0.583 3.08 -0.24 0.473 0.612 0.213 0.787 0.311 1.95 0.869 0.441 0.0487 1.312 2.38 1.04 5.78 PRS_PLINK_0.000199526231496888 FALSE 702.4 Degenerative skin disorders Both 1 8 13 dermatologic firebrick 8, 1 2, 1 2, 0 2, 0 2, 0 -0.7 3950000 1 0 0.497 0.159 2.8 -0.842 10600 1 0 0.431 1.67e-06 55300 0.0162 5670 1 0 1.02 0.56 1.84 1.29 5840 1 0 3.63 0.561 76200000 PRS_PLINK_0.000199526231496888 TRUE 703 Diseases of nail, NOS Both 24 108 13 dermatologic firebrick 108, 24 26, 8 27, 5 27, 5 27, 6 -0.0465 0.232 0.841 0.075 0.955 0.609 1.51 -0.0268 0.717 0.97 0.013 0.974 0.25 4 -0.239 0.713 0.738 0.132 0.788 0.194 3.27 0.454 0.715 0.526 0.279 1.57 0.407 6.84 PRS_PLINK_0.000199526231496888 TRUE 703.1 Ingrowing nail Both 13 68 13 dermatologic firebrick 68, 13 16, 3 17, 3 17, 4 17, 3 0.159 0.32 0.62 0.208 1.17 0.635 2.28 -0.0905 0.952 0.924 0.034 0.913 0.147 5.38 0.902 1.11 0.416 0.381 2.47 0.352 53.7 1.13 1.15 0.328 0.485 3.09 0.314 52.4 PRS_PLINK_0.000199526231496888 TRUE 704 Diseases of hair and hair follicles Both 73 295 13 dermatologic firebrick 295, 73 73, 13 74, 21 73, 16 74, 23 0.0953 0.137 0.485 0.314 1.1 0.844 1.44 0.355 0.41 0.386 0.413 1.43 0.643 3.24 0.083 0.42 0.843 0.074 1.09 0.479 2.49 0.495 0.399 0.216 0.666 1.64 0.759 3.65 PRS_PLINK_0.000199526231496888 FALSE 704.1 Alopecia Both 34 177 13 dermatologic firebrick 177, 34 44, 8 44, 7 44, 5 44, 14 0.247 0.208 0.236 0.628 1.28 0.855 1.94 -0.356 0.602 0.554 0.256 0.7 0.207 2.3 -0.488 0.592 0.41 0.387 0.614 0.178 1.95 0.933 0.557 0.0938 1.028 2.54 0.89 7.97 PRS_PLINK_0.000199526231496888 TRUE 704.11 Alopecia Areata Both 1 3 13 dermatologic firebrick 3, 1 1, 0 1, 0 1, 1 1, 0 -0.27 7450 1 0 0.764 0.032 3.97 -0.000953 40.2 1 0 0.999 0.969 1.03 PRS_PLINK_0.000199526231496888 TRUE 704.12 Telogen effluvium Both 0 8 13 dermatologic firebrick 8, 0 2 2 2 2 PRS_PLINK_0.000199526231496888 TRUE 704.2 Hirsutism Both 23 53 13 dermatologic firebrick 53, 23 13, 4 13, 8 13, 4 13, 7 0.0841 0.291 0.772 0.112 1.09 0.64 1.93 0.582 0.889 0.513 0.29 1.79 0.367 13.5 -0.0828 0.875 0.925 0.034 0.921 0.182 4.65 0.77 0.874 0.378 0.422 2.16 0.461 12.4 PRS_PLINK_0.000199526231496888 TRUE 704.8 Other specified diseases of hair and hair follicles Both 38 163 13 dermatologic firebrick 163, 38 40, 6 41, 11 40, 12 41, 9 0.119 0.189 0.529 0.277 1.13 0.782 1.64 0.694 0.572 0.225 0.648 2 0.682 6.31 0.634 0.563 0.26 0.584 1.89 0.66 5.84 0.503 0.573 0.381 0.42 1.65 0.547 5.22 PRS_PLINK_0.000199526231496888 TRUE 705 Disorders of sweat glands Both 20 68 13 dermatologic firebrick 68, 20 16, 5 17, 4 17, 5 17, 6 0.114 0.276 0.68 0.168 1.12 0.666 1.94 0.205 0.924 0.824 0.084 1.23 0.201 9.26 -0.194 0.815 0.812 0.09 0.824 0.177 3.87 0.934 0.987 0.344 0.464 2.54 0.451 17.3 PRS_PLINK_0.000199526231496888 TRUE 705.1 Dyshidrosis Both 7 16 13 dermatologic firebrick 16, 7 4, 2 4, 0 4, 2 4, 3 0.0292 0.608 0.962 0.017 1.03 0.174 3.06 4.54 2880000 1 0 93.7 0.165 43000 2.22 4.24 0.6 0.222 9.21 0.0076 11100 -0.000666 1.78 1 0 0.999 0.00123 15.7 PRS_PLINK_0.000199526231496888 TRUE 705.3 Hidradenitis Both 6 31 13 dermatologic firebrick 31, 6 8, 1 8, 3 7, 1 8, 1 0.000426 0.491 0.999 0 1 0.406 2.57 0.174 1.46 0.905 0.043 1.19 0.0951 17 -0.112 218 1 0 0.894 0.362 2.21 -1.27 2.46 0.604 0.219 0.28 0.000489 23.4 PRS_PLINK_0.000199526231496888 TRUE 705.8 Hyperhidrosis Both 22 100 13 dermatologic firebrick 100, 22 24, 5 25, 4 25, 4 25, 9 0.0963 0.266 0.717 0.144 1.1 0.663 1.89 -0.209 0.754 0.781 0.107 0.811 0.173 3.55 -0.558 0.813 0.493 0.308 0.573 0.104 2.61 0.787 0.716 0.272 0.566 2.2 0.591 9.55 PRS_PLINK_0.000199526231496888 TRUE 706 Diseases of sebaceous glands Both 141 290 13 dermatologic firebrick 290, 141 72, 29 72, 44 72, 32 73, 36 -0.0438 0.107 0.681 0.167 0.957 0.778 1.18 0.343 0.304 0.259 0.587 1.41 0.788 2.54 0.0236 0.32 0.941 0.026 1.02 0.551 1.9 0.0606 0.318 0.849 0.071 1.06 0.575 1.96 PRS_PLINK_0.000199526231496888 FALSE 706.1 Acne Both 84 238 13 dermatologic firebrick 238, 84 59, 15 59, 27 59, 19 60, 23 0.113 0.136 0.405 0.392 1.12 0.861 1.46 0.498 0.381 0.19 0.72 1.65 0.8 3.47 0.318 0.398 0.423 0.373 1.37 0.641 3.01 0.427 0.393 0.277 0.557 1.53 0.722 3.32 PRS_PLINK_0.000199526231496888 FALSE 706.2 Sebaceous cyst Both 52 183 13 dermatologic firebrick 183, 52 46, 13 46, 18 45, 5 46, 16 -0.0868 0.164 0.597 0.224 0.917 0.666 1.26 0.375 0.428 0.382 0.418 1.45 0.642 3.39 -1.08 0.582 0.0641 1.193 0.341 0.0998 1.02 -0.0753 0.467 0.872 0.06 0.927 0.375 2.26 PRS_PLINK_0.000199526231496888 FALSE 706.3 Seborrhea Both 0 4 13 dermatologic firebrick 4, 0 1 1 1 1 PRS_PLINK_0.000199526231496888 TRUE 706.8 Other specified diseases of sebaceous glands Both 22 92 13 dermatologic firebrick 92, 22 23, 6 23, 8 23, 4 23, 4 -0.248 0.241 0.304 0.518 0.781 0.485 1.23 0.0786 0.693 0.91 0.041 1.08 0.282 4.15 0.0384 0.764 0.96 0.018 1.04 0.237 4.65 -0.267 0.759 0.725 0.14 0.765 0.167 3.14 PRS_PLINK_0.000199526231496888 TRUE 707 Chronic ulcer of skin Both 32 207 13 dermatologic firebrick 207, 32 51, 10 52, 7 51, 6 52, 9 -0.0804 0.187 0.668 0.176 0.923 0.637 1.34 -0.284 0.541 0.6 0.222 0.753 0.25 2.17 -0.403 0.556 0.468 0.33 0.668 0.211 1.98 -0.0293 0.489 0.952 0.021 0.971 0.37 2.54 PRS_PLINK_0.000199526231496888 TRUE 707.1 Decubitus ulcer Both 5 47 13 dermatologic firebrick 47, 5 12, 2 12, 2 11, 1 12, 0 -0.251 0.554 0.651 0.187 0.778 0.167 2.53 -0.0653 1.16 0.955 0.02 0.937 0.0853 8.94 -0.554 1.42 0.697 0.157 0.575 0.000965 15.4 -1.43 1.54 0.353 0.452 0.239 0.000348 3.96 PRS_PLINK_0.000199526231496888 TRUE 707.2 Chronic ulcer of leg or foot Both 12 64 13 dermatologic firebrick 64, 12 16, 5 16, 1 16, 2 16, 4 -0.19 0.32 0.552 0.258 0.827 0.435 1.54 -2.44 1.38 0.0782 1.107 0.0876 0.0022 0.919 -2.44 1.37 0.0747 1.126 0.0876 0.00121 0.907 -0.0773 0.848 0.927 0.033 0.926 0.176 4.38 PRS_PLINK_0.000199526231496888 TRUE 707.3 Chronic ulcer of unspecified site Both 22 133 13 dermatologic firebrick 133, 22 33, 3 33, 7 33, 5 33, 7 0.199 0.244 0.415 0.382 1.22 0.754 2.03 0.713 0.807 0.377 0.424 2.04 0.419 11.5 0.154 0.734 0.834 0.079 1.17 0.258 5.54 0.847 0.708 0.232 0.635 2.33 0.6 10.8 PRS_PLINK_0.000199526231496888 TRUE 709 Diffuse diseases of connective tissue Both 25 138 13 dermatologic firebrick 138, 25 34, 7 34, 10 34, 2 35, 6 -0.205 0.247 0.406 0.391 0.814 0.498 1.33 -1.07 0.804 0.183 0.737 0.343 0.0611 1.5 -1.64 0.893 0.0663 1.179 0.194 0.0207 1 -0.193 0.68 0.776 0.11 0.824 0.215 3.01 PRS_PLINK_0.000199526231496888 TRUE 709.2 Sicca syndrome Both 6 31 13 dermatologic firebrick 31, 6 8, 2 8, 1 7, 0 8, 3 -0.045 0.674 0.947 0.024 0.956 0.188 4.01 -0.513 2.08 0.805 0.094 0.599 0.0013 85.6 -1.32 1.65 0.423 0.373 0.267 0.000265 3.55 -0.427 1.52 0.778 0.109 0.653 0.00467 928 PRS_PLINK_0.000199526231496888 TRUE 709.3 Systemic sclerosis Both 1 19 13 dermatologic firebrick 19, 1 5, 0 5, 1 4, 0 5, 0 -0.152 0.848 0.858 0.067 0.859 0.0331 10.7 -1.5 3.85 0.697 0.157 0.224 0.000218 1950 PRS_PLINK_0.000199526231496888 TRUE 709.5 Dermatomyositis Both 1 8 13 dermatologic firebrick 8, 1 2, 1 2, 0 2, 0 2, 0 1.24 8.44 0.883 0.054 3.46 1.64e-05 2870000 0.0116 329 1 0 1.01 0.793 1.34 -0.434 1110 1 0 0.648 0.00581 18.2 0.623 1940 1 0 1.86 0.0483 46.2 PRS_PLINK_0.000199526231496888 TRUE 709.6 Other specified diffuse diseases of connective tissue Both 2 6 13 dermatologic firebrick 6, 2 2, 1 1, 1 1, 0 2, 0 -0.142 23.9 0.995 0.002 0.867 0.818 0.875 -1.34 25000 1 0 0.263 0.0422 15.6 0.129 10700 1 0 1.14 0.58 2.31 0.00552 323 1 0 1.01 0.398 2.09 PRS_PLINK_0.000199526231496888 TRUE 709.7 Unspecified diffuse connective tissue disease Both 19 88 13 dermatologic firebrick 88, 19 22, 4 22, 8 22, 3 22, 4 -0.188 0.294 0.522 0.282 0.828 0.468 1.46 -0.94 1.04 0.364 0.439 0.391 0.0388 2.59 -1.84 1.27 0.148 0.831 0.159 1.83e-05 1.6 -0.325 0.885 0.713 0.147 0.723 0.12 3.72 PRS_PLINK_0.000199526231496888 TRUE 710 Osteomyelitis, periostitis, and other infections involving bone Both 10 66 14 musculoskeletal darkolivegreen 66, 10 17, 4 16, 3 16, 0 17, 3 -0.128 0.34 0.705 0.152 0.879 0.448 1.7 0.388 0.96 0.686 0.163 1.47 0.216 17.5 -1.81 1.3 0.163 0.788 0.163 1.19e-05 1.88 -0.494 0.89 0.579 0.238 0.61 0.0968 3.13 PRS_PLINK_0.000199526231496888 TRUE 710.1 Osteomyelitis Both 10 59 14 musculoskeletal darkolivegreen 59, 10 15, 4 15, 3 14, 0 15, 3 -0.103 0.336 0.759 0.12 0.902 0.463 1.72 0.4 0.996 0.688 0.163 1.49 0.219 13.5 -1.6 1.31 0.219 0.659 0.201 0.000604 2.43 -0.551 0.916 0.548 0.261 0.576 0.0886 3.02 PRS_PLINK_0.000199526231496888 TRUE 710.11 Acute osteomyelitis Both 5 29 14 musculoskeletal darkolivegreen 29, 5 8, 2 7, 2 7, 0 7, 1 -0.106 0.436 0.808 0.093 0.899 0.382 1.99 0.29 1.74 0.868 0.062 1.34 0.00605 754 -1.06 1.73 0.539 0.268 0.347 0.000229 12.9 0.178 2.52 0.944 0.025 1.2 0.00363 462 PRS_PLINK_0.000199526231496888 TRUE 710.12 Chronic osteomyelitis Both 7 24 14 musculoskeletal darkolivegreen 24, 7 6, 4 6, 1 6, 0 6, 2 -0.392 0.469 0.403 0.394 0.676 0.236 1.51 -1.08 1.82 0.553 0.257 0.341 0.00401 8.93 -2.51 2.2 0.254 0.595 0.081 3.67e-05 2.71 -0.78 1.33 0.556 0.255 0.459 0.0277 6.69 PRS_PLINK_0.000199526231496888 TRUE 710.19 Unspecified osteomyelitis Both 10 55 14 musculoskeletal darkolivegreen 55, 10 14, 4 14, 3 13, 0 14, 3 -0.126 0.341 0.712 0.148 0.882 0.449 1.68 0.213 0.987 0.829 0.081 1.24 0.183 11.7 -1.73 1.34 0.194 0.711 0.177 0.000161 2.08 -0.407 0.89 0.648 0.189 0.666 0.111 3.33 PRS_PLINK_0.000199526231496888 TRUE 711 Arthropathy associated with infections Both 5 20 14 musculoskeletal darkolivegreen 20, 5 5, 1 5, 2 5, 1 5, 1 -0.092 0.697 0.895 0.048 0.912 0.233 3.54 0.652 2.56 0.799 0.097 1.92 0.00604 3190 -0.353 1.82 0.846 0.073 0.702 0.0247 18.7 -0.733 1.96 0.708 0.15 0.48 2.07e-05 24.4 PRS_PLINK_0.000199526231496888 TRUE 711.1 Pyogenic arthritis Both 3 14 14 musculoskeletal darkolivegreen 14, 3 4, 1 3, 1 3, 0 4, 1 -0.367 0.814 0.652 0.185 0.693 0.152 2.89 -0.201 5.97 0.973 0.012 0.818 0.791 0.836 -1.24 10300000 1 0 0.29 0.0488 1.78 -0.275 2.08 0.895 0.048 0.76 0.686 0.795 PRS_PLINK_0.000199526231496888 TRUE 712 Infective connective tissue disorders Both 2 10 14 musculoskeletal darkolivegreen 10, 2 3, 0 2, 0 2, 0 3, 2 0.0513 1.04 0.961 0.017 1.05 0.997 21.5 0.286 33.6 0.993 0.003 1.33 0.2 8.88 PRS_PLINK_0.000199526231496888 TRUE 713 Arthropathy associated with other disorders classified elsewhere Both 1 17 14 musculoskeletal darkolivegreen 17, 1 5, 1 4, 0 4, 0 4, 0 -0.305 1.07 0.776 0.11 0.737 0.0349 5.71 -2.38e-14 3.8 1 0 1 0.00288 229 0.15 950000 1 0 1.16 0.641 3.22 -1.86 21.7 0.932 0.031 0.155 0.0117 0.141 PRS_PLINK_0.000199526231496888 TRUE 713.5 Arthropathy associated with neurological disorders Both 1 4 14 musculoskeletal darkolivegreen 4, 1 1, 1 1, 0 1, 0 1, 0 -0.0729 4530 1 0 0.93 0.492 1.43 0.00224 63.2 1 0 1 0.915 1.09 0.00404 25.8 1 0 1 0.948 1.08 0.0101 82.8 1 0 1.01 0.915 1.11 PRS_PLINK_0.000199526231496888 TRUE 714 Rheumatoid arthritis and other inflammatory polyarthropathies Both 20 158 14 musculoskeletal darkolivegreen 158, 20 40, 7 39, 7 39, 2 40, 4 -0.192 0.265 0.467 0.331 0.825 0.486 1.38 -0.439 0.676 0.517 0.287 0.645 0.161 2.44 -1.01 0.808 0.211 0.676 0.364 0.0543 1.76 -0.637 0.652 0.329 0.483 0.529 0.134 1.83 PRS_PLINK_0.000199526231496888 TRUE 714.1 Rheumatoid arthritis Both 15 119 14 musculoskeletal darkolivegreen 119, 15 30, 4 30, 6 29, 2 30, 3 0.0763 0.321 0.812 0.09 1.08 0.572 2.05 0.109 0.824 0.894 0.048 1.12 0.211 6.03 -0.755 0.993 0.447 0.35 0.47 0.045 3.42 -0.314 0.77 0.683 0.165 0.73 0.142 3.33 PRS_PLINK_0.000199526231496888 TRUE 714.2 Juvenile rheumatoid arthritis Both 0 9 14 musculoskeletal darkolivegreen 9, 0 3 2 2 2 PRS_PLINK_0.000199526231496888 TRUE 715 Other inflammatory spondylopathies Both 15 77 14 musculoskeletal darkolivegreen 77, 15 20, 5 19, 3 19, 3 19, 4 -0.23 0.313 0.462 0.335 0.794 0.422 1.47 -0.149 0.907 0.87 0.061 0.862 0.138 5.39 -0.281 0.868 0.746 0.127 0.755 0.12 4.61 -0.0907 0.936 0.923 0.035 0.913 0.139 5.83 PRS_PLINK_0.000199526231496888 TRUE 715.1 Sacroiliitis NEC Both 7 30 14 musculoskeletal darkolivegreen 30, 7 8, 2 7, 3 7, 1 8, 1 -0.141 0.475 0.766 0.116 0.868 0.331 2.22 0.554 1.26 0.66 0.181 1.74 0.203 95.2 -1.41 1.76 0.423 0.373 0.244 0.000203 3.73 0.533 1.73 0.758 0.12 1.7 0.0269 1.39e+11 PRS_PLINK_0.000199526231496888 TRUE 715.2 Ankylosing spondylitis Both 1 18 14 musculoskeletal darkolivegreen 18, 1 5, 0 4, 1 4, 0 5, 0 -0.091 1.02 0.929 0.032 0.913 0.0728 6.35 0.708 4.35 0.871 0.06 2.03 0.0014 1400 PRS_PLINK_0.000199526231496888 TRUE 716 Other arthropathies Both 131 304 14 musculoskeletal darkolivegreen 304, 131 75, 35 76, 43 76, 21 76, 32 -0.0779 0.12 0.517 0.287 0.925 0.732 1.17 0.342 0.314 0.275 0.56 1.41 0.769 2.6 -0.796 0.408 0.0512 1.291 0.451 0.198 0.981 -0.0712 0.342 0.835 0.078 0.931 0.48 1.8 PRS_PLINK_0.000199526231496888 FALSE 716.1 Unspecified polyarthropathy or polyarthritis Both 6 14 14 musculoskeletal darkolivegreen 14, 6 4, 4 3, 1 3, 0 4, 1 -0.0313 0.828 0.97 0.013 0.969 0.183 7.6 -1.74 4.34 0.689 0.162 0.176 0.161 66.7 -0.962 6.28 0.878 0.056 0.382 3.47e-06 4950 0.54 2.07 0.794 0.1 1.72 0.0789 77.7 PRS_PLINK_0.000199526231496888 TRUE 716.2 Unspecified monoarthritis Both 1 13 14 musculoskeletal darkolivegreen 13, 1 4, 1 3, 0 3, 0 3, 0 0.628 1.34 0.64 0.194 1.87 0.146 147 -2.41 268 0.993 0.003 0.09 0.0915 1.64 -0.00221 24.2 1 0 0.998 0.9 1.12 0.0196 212 1 0 1.02 34.8 54.5 PRS_PLINK_0.000199526231496888 TRUE 716.9 Arthropathy NOS Both 128 304 14 musculoskeletal darkolivegreen 304, 128 75, 34 76, 42 76, 21 76, 31 -0.0793 0.121 0.513 0.29 0.924 0.729 1.17 0.341 0.318 0.285 0.546 1.41 0.761 2.62 -0.78 0.41 0.0571 1.243 0.458 0.201 1 -0.0671 0.344 0.845 0.073 0.935 0.48 1.82 PRS_PLINK_0.000199526231496888 FALSE 717 Polymyalgia Rheumatica Both 1 13 14 musculoskeletal darkolivegreen 13, 1 4, 1 3, 0 3, 0 3, 0 -0.545 2.31 0.814 0.09 0.58 0.000312 21 -0.0104 327 1 0 0.99 0.74 1.27 -0.309 453 0.999 0 0.735 2.59 0.711 0.347 541 0.999 0 1.41 1.71 6.66 PRS_PLINK_0.000199526231496888 TRUE 720 Spinal stenosis Both 34 163 14 musculoskeletal darkolivegreen 163, 34 41, 13 41, 8 40, 5 41, 8 -0.526 0.271 0.0519 1.285 0.591 0.336 0.999 -0.799 0.705 0.257 0.589 0.45 0.104 1.75 -1.6 0.742 0.0312 1.505 0.202 0.0375 0.799 -0.663 0.636 0.297 0.527 0.515 0.136 1.75 PRS_PLINK_0.000199526231496888 TRUE 720.1 Spinal stenosis of lumbar region Both 25 120 14 musculoskeletal darkolivegreen 120, 25 30, 11 30, 4 30, 5 30, 5 -0.616 0.359 0.0867 1.062 0.54 0.252 1.08 -0.746 0.916 0.415 0.382 0.474 0.0645 2.91 -1.15 0.769 0.134 0.873 0.316 0.0582 1.32 -0.943 0.867 0.277 0.558 0.39 0.0536 1.99 PRS_PLINK_0.000199526231496888 TRUE 721 Spondylosis and allied disorders Both 63 264 14 musculoskeletal darkolivegreen 264, 63 65, 23 66, 12 66, 13 66, 15 -0.088 0.161 0.584 0.234 0.916 0.666 1.26 -0.515 0.451 0.254 0.596 0.598 0.242 1.43 -0.793 0.444 0.0741 1.13 0.453 0.184 1.05 -0.389 0.443 0.381 0.419 0.678 0.279 1.6 PRS_PLINK_0.000199526231496888 FALSE 721.1 Spondylosis without myelopathy Both 59 256 14 musculoskeletal darkolivegreen 256, 59 64, 22 64, 11 64, 13 64, 13 -0.143 0.168 0.394 0.404 0.867 0.621 1.2 -0.559 0.468 0.232 0.634 0.572 0.222 1.41 -0.721 0.447 0.106 0.973 0.486 0.197 1.14 -0.452 0.454 0.32 0.495 0.637 0.256 1.52 PRS_PLINK_0.000199526231496888 FALSE 721.2 Spondylosis with myelopathy Both 15 41 14 musculoskeletal darkolivegreen 41, 15 11, 7 10, 4 10, 2 10, 2 -0.715 0.435 0.1 0.998 0.489 0.194 1.06 0.191 1.03 0.852 0.069 1.21 0.157 9.3 -0.87 1.09 0.424 0.372 0.419 0.0428 3 -1.34 1.1 0.225 0.648 0.262 0.0241 1.68 PRS_PLINK_0.000199526231496888 TRUE 721.8 Other allied disorders of spine Both 4 15 14 musculoskeletal darkolivegreen 15, 4 4, 1 4, 0 3, 2 4, 1 0.66 0.755 0.382 0.418 1.93 0.53 23.5 1.19 19.3 0.951 0.022 3.28 3.05 3.53 0.0767 2.98 0.979 0.009 1.08 0.0096 1320 0.481 1.77 0.786 0.105 1.62 0.11 127 PRS_PLINK_0.000199526231496888 TRUE 722 Intervertebral disc disorders Both 78 297 14 musculoskeletal darkolivegreen 297, 78 74, 24 74, 19 74, 17 74, 18 -0.133 0.152 0.382 0.418 0.876 0.649 1.18 -0.215 0.41 0.6 0.222 0.806 0.36 1.79 -0.621 0.423 0.142 0.846 0.538 0.229 1.21 -0.237 0.413 0.566 0.247 0.789 0.35 1.76 PRS_PLINK_0.000199526231496888 FALSE 722.1 Displacement of intervertebral disc Both 46 249 14 musculoskeletal darkolivegreen 249, 46 63, 14 62, 11 62, 8 62, 13 -0.0818 0.186 0.661 0.18 0.921 0.637 1.33 -0.417 0.477 0.382 0.418 0.659 0.253 1.66 -0.833 0.521 0.11 0.959 0.435 0.146 1.18 -0.165 0.473 0.728 0.138 0.848 0.333 2.12 PRS_PLINK_0.000199526231496888 TRUE 722.3 Schmorl's nodes Both 1 11 14 musculoskeletal darkolivegreen 11, 1 3, 1 3, 0 2, 0 3, 0 -0.284 0.967 0.769 0.114 0.752 0.0122 3.5 0.188 1480 1 0 1.21 0.741 1.26 -0.184 1.7e+07 1 0 0.832 0.0324 84.4 -0.558 4450000 1 0 0.572 0.038 3.95 PRS_PLINK_0.000199526231496888 TRUE 722.6 Degeneration of intervertebral disc Both 54 214 14 musculoskeletal darkolivegreen 214, 54 54, 18 53, 13 53, 10 54, 13 -0.0731 0.179 0.683 0.165 0.93 0.652 1.32 -0.106 0.466 0.82 0.086 0.899 0.36 2.25 -0.744 0.516 0.149 0.827 0.475 0.164 1.27 -0.223 0.49 0.649 0.188 0.8 0.303 2.07 PRS_PLINK_0.000199526231496888 FALSE 722.7 Intervertebral disc disorder with myelopathy Both 5 35 14 musculoskeletal darkolivegreen 35, 5 9, 3 9, 0 8, 1 9, 1 -1.57 1.04 0.13 0.885 0.209 0.00069 1.46 -0.641 1.52 0.674 0.172 0.527 4.08e-08 8.32 -0.848 1.36 0.534 0.272 0.428 0.000131 4.18 -1.12 1.4 0.424 0.373 0.326 0.00151 3.39 PRS_PLINK_0.000199526231496888 TRUE 722.8 Postlaminectomy syndrome Both 5 24 14 musculoskeletal darkolivegreen 24, 5 6, 1 6, 2 6, 2 6, 0 -0.0517 0.697 0.941 0.026 0.95 0.191 4.14 2.09 2.26 0.355 0.45 8.1 0.266 1.46e+09 2.18 3.11 0.484 0.315 8.84 0.0013 11.7 -0.629 2.8 0.822 0.085 0.533 0.452 397 PRS_PLINK_0.000199526231496888 TRUE 722.9 Other and unspecified disc disorder Both 31 139 14 musculoskeletal darkolivegreen 139, 31 34, 5 35, 12 34, 9 35, 5 -0.102 0.232 0.66 0.181 0.903 0.571 1.42 0.937 0.615 0.128 0.894 2.55 0.811 9.32 0.243 0.706 0.731 0.136 1.27 0.323 5.3 0.0794 0.692 0.909 0.042 1.08 0.267 4.41 PRS_PLINK_0.000199526231496888 TRUE 723 Other disorders of cervical region Both 12 89 14 musculoskeletal darkolivegreen 89, 12 23, 6 22, 0 22, 1 22, 5 -0.412 0.32 0.198 0.702 0.663 0.336 1.26 -2.23 1.19 0.0619 1.208 0.108 0.00103 0.815 -2.03 1.16 0.0795 1.1 0.132 0.0052 1.03 -0.547 0.765 0.475 0.324 0.579 0.125 2.43 PRS_PLINK_0.000199526231496888 TRUE 723.1 Torticollis Both 1 19 14 musculoskeletal darkolivegreen 19, 1 5, 0 5, 0 4, 0 5, 1 0.0755 1.18 0.949 0.023 1.08 0.0463 21 -0.000114 22.4 1 0 1 0.00154 660 PRS_PLINK_0.000199526231496888 TRUE 724 Other and unspecified disorders of back Both 79 291 14 musculoskeletal darkolivegreen 291, 79 72, 28 73, 14 72, 18 73, 19 -0.128 0.138 0.354 0.45 0.88 0.67 1.15 -0.606 0.393 0.123 0.908 0.546 0.249 1.16 -0.545 0.379 0.151 0.822 0.58 0.273 1.2 -0.299 0.366 0.414 0.383 0.741 0.361 1.5 PRS_PLINK_0.000199526231496888 FALSE 724.1 Disorders of sacrum Both 54 216 14 musculoskeletal darkolivegreen 216, 54 53, 19 54, 8 54, 12 54, 15 -0.0583 0.166 0.726 0.139 0.943 0.681 1.31 -0.628 0.477 0.188 0.725 0.534 0.204 1.33 -0.601 0.448 0.18 0.745 0.548 0.223 1.29 -0.137 0.418 0.744 0.129 0.872 0.387 1.95 PRS_PLINK_0.000199526231496888 FALSE 724.2 Disorders of coccyx Both 16 33 14 musculoskeletal darkolivegreen 33, 16 9, 3 8, 1 8, 6 8, 6 0.397 0.343 0.246 0.609 1.49 0.811 2.99 0.185 1.57 0.907 0.043 1.2 0.0399 38.4 0.462 0.993 0.641 0.193 1.59 0.282 10.6 0.984 1.22 0.422 0.375 2.68 0.307 28.6 PRS_PLINK_0.000199526231496888 TRUE 724.8 Other symptoms referable to back Both 21 77 14 musculoskeletal darkolivegreen 77, 21 19, 8 19, 2 19, 6 19, 5 -0.0258 0.301 0.932 0.031 0.975 0.535 1.77 -0.457 0.86 0.595 0.226 0.633 0.105 3.37 -0.528 0.747 0.48 0.319 0.59 0.141 2.31 0.187 0.778 0.81 0.091 1.21 0.276 5.52 PRS_PLINK_0.000199526231496888 TRUE 724.9 Other unspecified back disorders Both 20 99 14 musculoskeletal darkolivegreen 99, 20 24, 10 25, 1 24, 5 25, 4 -0.384 0.284 0.176 0.754 0.681 0.385 1.18 -1.94 1.06 0.0679 1.168 0.143 0.00591 0.949 -0.898 0.704 0.202 0.694 0.408 0.0929 1.48 -0.524 0.74 0.479 0.32 0.592 0.132 2.35 PRS_PLINK_0.000199526231496888 TRUE 726 Peripheral enthesopathies and allied syndromes Both 155 213 14 musculoskeletal darkolivegreen 213, 155 53, 34 53, 45 53, 40 53, 36 0.0427 0.119 0.719 0.143 1.04 0.829 1.32 0.585 0.344 0.0897 1.047 1.79 0.927 3.53 0.249 0.342 0.466 0.332 1.28 0.669 2.49 0.103 0.36 0.775 0.111 1.11 0.552 2.23 PRS_PLINK_0.000199526231496888 FALSE 726.1 Enthesopathy Both 113 213 14 musculoskeletal darkolivegreen 213, 113 53, 26 53, 32 53, 28 53, 27 0.0381 0.133 0.775 0.111 1.04 0.802 1.35 0.481 0.384 0.211 0.676 1.62 0.772 3.45 0.0139 0.387 0.971 0.013 1.01 0.481 2.14 0.18 0.396 0.648 0.188 1.2 0.557 2.59 PRS_PLINK_0.000199526231496888 FALSE 726.2 Synoviopathy Both 12 56 14 musculoskeletal darkolivegreen 56, 12 14, 6 14, 2 14, 3 14, 1 -0.654 0.393 0.0965 1.015 0.52 0.203 1.09 -1.38 1.2 0.252 0.598 0.253 0.00929 2.08 -1.08 1.11 0.332 0.479 0.34 0.0263 2.46 -1.2 1.12 0.284 0.546 0.3 0.0211 2.32 PRS_PLINK_0.000199526231496888 TRUE 726.3 Bursitis Both 32 105 14 musculoskeletal darkolivegreen 105, 32 27, 5 26, 12 26, 10 26, 5 0.251 0.225 0.264 0.578 1.29 0.839 2.01 1.39 0.672 0.039 1.409 4 1.17 16.7 1.4 0.76 0.0647 1.189 4.07 1.05 19.5 0.702 0.928 0.449 0.348 2.02 0.353 14.6 PRS_PLINK_0.000199526231496888 TRUE 726.4 Calcaneal spur; Exostosis NOS Both 17 69 14 musculoskeletal darkolivegreen 69, 17 18, 3 17, 5 17, 5 17, 4 0.0253 0.321 0.937 0.028 1.03 0.548 1.92 0.552 0.839 0.511 0.292 1.74 0.359 9.41 0.22 0.983 0.823 0.085 1.25 0.192 8.51 0.00831 0.877 0.992 0.003 1.01 0.188 5.92 PRS_PLINK_0.000199526231496888 TRUE 727 Other disorders of synovium, tendon, and bursa Both 105 213 14 musculoskeletal darkolivegreen 213, 105 53, 26 53, 27 53, 28 53, 24 -0.037 0.134 0.782 0.107 0.964 0.743 1.25 0.244 0.392 0.533 0.273 1.28 0.599 2.74 -0.0578 0.398 0.884 0.053 0.944 0.438 2.03 -0.0196 0.395 0.96 0.018 0.981 0.455 2.11 PRS_PLINK_0.000199526231496888 FALSE 727.1 Synovitis and tenosynovitis Both 43 186 14 musculoskeletal darkolivegreen 186, 43 46, 9 46, 9 46, 12 47, 13 0.124 0.178 0.488 0.312 1.13 0.801 1.61 0.124 0.544 0.82 0.086 1.13 0.386 3.3 0.209 0.527 0.692 0.16 1.23 0.446 3.49 0.648 0.545 0.234 0.63 1.91 0.68 5.7 PRS_PLINK_0.000199526231496888 TRUE 727.2 Bursitis disorders Both 2 27 14 musculoskeletal darkolivegreen 27, 2 7, 0 7, 1 6, 1 7, 0 -0.335 0.681 0.622 0.206 0.715 0.0274 3.86 -0.624 2.44 0.799 0.098 0.536 0.00128 49.9 0.834 3.38 0.805 0.094 2.3 0.000831 53400 PRS_PLINK_0.000199526231496888 TRUE 727.4 Ganglion and cyst of synovium, tendon, and bursa Both 26 88 14 musculoskeletal darkolivegreen 88, 26 22, 11 22, 6 22, 6 22, 3 -0.596 0.259 0.0213 1.672 0.551 0.323 0.888 -0.546 0.753 0.469 0.329 0.58 0.131 2.32 -0.83 0.742 0.263 0.58 0.436 0.0945 1.67 -1.61 0.873 0.0644 1.191 0.199 0.0296 0.912 PRS_PLINK_0.000199526231496888 TRUE 727.5 Rupture of synovium Both 11 24 14 musculoskeletal darkolivegreen 24, 11 6, 3 6, 3 6, 3 6, 2 -0.328 0.464 0.479 0.32 0.72 0.25 1.6 0.238 1.25 0.849 0.071 1.27 0.0607 11 0.409 1.59 0.797 0.098 1.5 0.0469 261 0.0208 1.91 0.991 0.004 1.02 0.0262 110 PRS_PLINK_0.000199526231496888 TRUE 727.6 Rupture of tendon, nontraumatic Both 26 84 14 musculoskeletal darkolivegreen 84, 26 21, 4 21, 7 21, 11 21, 4 0.175 0.248 0.481 0.318 1.19 0.738 1.96 1.46 0.9 0.105 0.979 4.3 0.826 33.1 1.12 0.766 0.143 0.844 3.07 0.772 15.9 0.216 0.972 0.824 0.084 1.24 0.176 16.5 PRS_PLINK_0.000199526231496888 TRUE 727.7 Contracture of tendon (sheath) Both 11 54 14 musculoskeletal darkolivegreen 54, 11 14, 2 13, 1 13, 6 14, 2 0.305 0.383 0.426 0.371 1.36 0.65 2.97 1.72 1.72 0.315 0.501 5.6 0.266 2730 1.46 1.37 0.287 0.542 4.3 0.374 222 1.27 1.47 0.389 0.41 3.55 0.229 752 PRS_PLINK_0.000199526231496888 TRUE 727.8 Plica syndrome Both 1 17 14 musculoskeletal darkolivegreen 17, 1 5, 0 4, 0 4, 0 4, 1 -0.0469 1.04 0.964 0.016 0.954 0.0158 60.1 -0.336 3.11 0.914 0.039 0.715 0.00277 168 PRS_PLINK_0.000199526231496888 TRUE 728 Disorders of muscle, ligament, and fascia Both 66 210 14 musculoskeletal darkolivegreen 210, 66 52, 13 52, 24 52, 22 53, 7 -0.136 0.16 0.395 0.403 0.873 0.638 1.19 0.622 0.445 0.162 0.79 1.86 0.802 4.49 0.482 0.447 0.281 0.552 1.62 0.695 3.92 -0.856 0.575 0.137 0.863 0.425 0.129 1.25 PRS_PLINK_0.000199526231496888 FALSE 728.1 Muscular calcification and ossification Both 1 4 14 musculoskeletal darkolivegreen 4, 1 1, 0 1, 0 1, 0 1, 1 0.139 1920 1 0 1.15 0.743 3.99 -0.00368 109 1 0 0.996 0.973 1.03 PRS_PLINK_0.000199526231496888 TRUE 728.2 Laxity of ligament or hypermobility syndrome Both 5 18 14 musculoskeletal darkolivegreen 18, 5 5, 1 4, 0 4, 2 5, 2 0.151 0.951 0.874 0.059 1.16 0.0814 66.5 -0.0552 793 1 0 0.946 0.00733 30.9 2.05 4.29 0.633 0.198 7.73 0.0087 13200 0.337 2.23 0.88 0.056 1.4 0.000263 78.7 PRS_PLINK_0.000199526231496888 TRUE 728.7 Fasciitis Both 56 154 14 musculoskeletal darkolivegreen 154, 56 38, 13 38, 17 38, 14 39, 12 -0.236 0.181 0.192 0.717 0.79 0.553 1.12 0.563 0.491 0.251 0.6 1.76 0.692 4.64 -0.205 0.511 0.688 0.162 0.815 0.305 2.14 -0.446 0.592 0.451 0.345 0.64 0.196 1.97 PRS_PLINK_0.000199526231496888 FALSE 728.71 Contracture of palmar fascia [Dupuytren's disease] Both 2 15 14 musculoskeletal darkolivegreen 15, 2 4, 0 4, 2 3, 0 4, 0 -1.43 1.48 0.333 0.478 0.238 0.0028 3.52 0.692 7.65 0.928 0.033 2 5.97e-05 1780000 PRS_PLINK_0.000199526231496888 TRUE 729 Other disorders of soft tissues Both 61 181 14 musculoskeletal darkolivegreen 181, 61 45, 20 45, 17 45, 14 45, 10 -0.259 0.159 0.105 0.98 0.772 0.564 1.05 -0.285 0.442 0.519 0.285 0.752 0.316 1.76 -0.738 0.486 0.129 0.89 0.478 0.182 1.19 -0.714 0.484 0.14 0.853 0.49 0.187 1.21 PRS_PLINK_0.000199526231496888 FALSE 729.1 Rheumatism, unspecified and fibrositis Both 0 9 14 musculoskeletal darkolivegreen 9, 0 3 2 2 2 PRS_PLINK_0.000199526231496888 TRUE 729.3 Panniculitis Both 2 7 14 musculoskeletal darkolivegreen 7, 2 2, 1 2, 0 1, 0 2, 1 -0.804 3.76 0.831 0.081 0.448 0.423 0.47 -0.803 12600000 1 0 0.448 0.00057 46.3 -0.216 1680 1 0 0.806 0.0959 4.02 -0.0421 480 1 0 0.959 0.425 2.05 PRS_PLINK_0.000199526231496888 TRUE 729.7 Nontraumatic compartment syndrome Both 0 4 14 musculoskeletal darkolivegreen 4, 0 1 1 1 1 PRS_PLINK_0.000199526231496888 TRUE 731 Osteitis deformans and osteopathies associated with other disorders classified elsewhere Both 3 11 14 musculoskeletal darkolivegreen 11, 3 3, 0 3, 0 2, 0 3, 3 0.417 0.715 0.56 0.252 1.52 0.401 7.99 1.76 181 0.992 0.003 5.79 33.3 100 PRS_PLINK_0.000199526231496888 TRUE 732 Osteochondropathies Both 2 38 14 musculoskeletal darkolivegreen 38, 2 10, 0 9, 1 9, 0 10, 1 0.435 0.579 0.453 0.344 1.54 0.515 94.7 1.09 1.49 0.466 0.332 2.96 0.155 785 0.893 1.41 0.527 0.279 2.44 0.157 282000 PRS_PLINK_0.000199526231496888 TRUE 732.1 Juvenile osteochondrosis Both 1 15 14 musculoskeletal darkolivegreen 15, 1 4, 0 4, 1 3, 0 4, 0 0.115 0.631 0.855 0.068 1.12 0.229 18.6 0.967 108 0.993 0.003 2.63 0.798 31.6 PRS_PLINK_0.000199526231496888 TRUE 732.7 Osteochondritis dissecans Both 0 13 14 musculoskeletal darkolivegreen 13, 0 4 3 3 3 PRS_PLINK_0.000199526231496888 TRUE 733 Other disorders of bone and cartilage Both 57 226 14 musculoskeletal darkolivegreen 226, 57 57, 15 56, 18 56, 10 57, 14 -0.106 0.169 0.529 0.276 0.899 0.647 1.25 0.428 0.449 0.34 0.468 1.53 0.658 3.72 -0.221 0.575 0.701 0.154 0.802 0.253 2.46 -0.0137 0.476 0.977 0.01 0.986 0.394 2.47 PRS_PLINK_0.000199526231496888 FALSE 733.2 Cyst of bone Both 1 17 14 musculoskeletal darkolivegreen 17, 1 4, 1 4, 0 4, 0 4, 0 -0.0988 0.657 0.881 0.055 0.906 0.193 4.92 -0.22 8280000 1 0 0.803 0.228 2.99 -0.0154 20.8 0.999 0 0.985 0.0878 5.86 0.0681 50.7 0.999 0 1.07 0.947 1.73 PRS_PLINK_0.000199526231496888 TRUE 733.4 Aseptic necrosis of bone Both 6 25 14 musculoskeletal darkolivegreen 25, 6 7, 2 6, 0 6, 3 6, 1 -0.875 1.05 0.403 0.395 0.417 0.0045 3.3 -0.489 1.8 0.786 0.104 0.613 0.000451 14.9 -0.088 1.71 0.959 0.018 0.916 0.00373 623 -1.42 1.93 0.46 0.337 0.241 0.0031 4.63 PRS_PLINK_0.000199526231496888 TRUE 733.6 Costochondritis Both 11 35 14 musculoskeletal darkolivegreen 35, 11 9, 5 9, 2 8, 1 9, 3 0.0752 0.406 0.853 0.069 1.08 0.489 2.47 -0.78 1.35 0.564 0.249 0.458 0.0193 5.44 -0.722 1.45 0.618 0.209 0.486 0.00958 5.63 -0.0278 1.06 0.979 0.009 0.973 0.061 7.2 PRS_PLINK_0.000199526231496888 TRUE 733.8 Malunion and nonunion of fracture Both 4 57 14 musculoskeletal darkolivegreen 57, 4 15, 2 14, 2 14, 0 14, 0 -0.536 0.563 0.341 0.467 0.585 0.0498 3.16 -0.533 1.15 0.643 0.192 0.587 0.0322 5.36 -1.3 1.21 0.283 0.548 0.273 0.00222 3.22 -1.28 1.31 0.328 0.484 0.278 0.00159 5.22 PRS_PLINK_0.000199526231496888 TRUE 733.9 Chondromalacia Both 3 11 14 musculoskeletal darkolivegreen 11, 3 3, 0 3, 2 2, 0 3, 1 0.201 1.42 0.887 0.052 1.22 0.113 33.3 0.959 247 0.997 0.001 2.61 10.6 2030 -0.0222 1430 1 0 0.978 0.891 1.32 PRS_PLINK_0.000199526231496888 TRUE 735 Acquired foot deformities Both 56 236 14 musculoskeletal darkolivegreen 236, 56 59, 15 59, 18 59, 10 59, 13 -0.127 0.155 0.414 0.384 0.881 0.65 1.19 0.376 0.414 0.363 0.44 1.46 0.658 3.29 -0.507 0.471 0.282 0.549 0.602 0.235 1.49 -0.271 0.445 0.543 0.265 0.763 0.317 1.79 PRS_PLINK_0.000199526231496888 FALSE 735.1 Flat foot Both 11 42 14 musculoskeletal darkolivegreen 42, 11 11, 3 10, 4 10, 2 11, 2 -0.502 0.428 0.24 0.62 0.605 0.254 1.33 -0.298 1.07 0.782 0.107 0.743 0.0889 5.3 -0.648 1.25 0.605 0.218 0.523 0.0196 4.88 -0.59 1.07 0.581 0.236 0.554 0.0343 3.41 PRS_PLINK_0.000199526231496888 TRUE 735.2 Acquired toe deformities Both 18 71 14 musculoskeletal darkolivegreen 71, 18 18, 6 18, 5 17, 4 18, 3 -0.376 0.306 0.219 0.66 0.686 0.368 1.25 -0.117 0.782 0.881 0.055 0.89 0.197 3.99 -0.558 0.868 0.52 0.284 0.572 0.0972 2.91 -0.841 0.894 0.347 0.46 0.431 0.0524 2.41 PRS_PLINK_0.000199526231496888 TRUE 735.21 Hammer toe (acquired) Both 13 41 14 musculoskeletal darkolivegreen 41, 13 11, 4 10, 3 10, 5 10, 1 -0.209 0.382 0.583 0.234 0.811 0.377 1.71 1.36 1.72 0.43 0.366 3.88 0.164 137 0.932 1.16 0.421 0.376 2.54 0.331 30.1 -0.862 1.27 0.499 0.302 0.422 0.0284 3.6 PRS_PLINK_0.000199526231496888 TRUE 735.23 Hallux rigidus Both 4 20 14 musculoskeletal darkolivegreen 20, 4 5, 2 5, 0 5, 1 5, 1 -1.96 1.44 0.174 0.759 0.141 1.63e-10 1.48 -0.653 2.48 0.792 0.101 0.52 0.282 0.604 -2.83 2.51 0.258 0.589 0.0587 1.37e-05 1.76 -1.1 2.47 0.657 0.183 0.333 0.00232 14.8 PRS_PLINK_0.000199526231496888 TRUE 735.3 Hallux valgus (Bunion) Both 29 121 14 musculoskeletal darkolivegreen 121, 29 31, 6 30, 9 30, 6 30, 8 -0.0975 0.231 0.673 0.172 0.907 0.574 1.43 0.312 0.639 0.626 0.204 1.37 0.39 4.84 -0.244 0.709 0.731 0.136 0.783 0.19 3.19 -0.192 0.676 0.776 0.11 0.825 0.216 3.08 PRS_PLINK_0.000199526231496888 TRUE 736 Other acquired deformities of limbs Both 48 217 14 musculoskeletal darkolivegreen 217, 48 55, 10 54, 19 54, 6 54, 13 0.0299 0.168 0.858 0.066 1.03 0.742 1.43 0.727 0.461 0.115 0.939 2.07 0.863 5.19 -0.335 0.557 0.547 0.262 0.715 0.227 2.13 0.159 0.5 0.75 0.125 1.17 0.442 3.13 PRS_PLINK_0.000199526231496888 TRUE 736.1 Acquired deformities of forearm Both 0 8 14 musculoskeletal darkolivegreen 8, 0 2 2 2 2 PRS_PLINK_0.000199526231496888 TRUE 736.2 Acquired deformities of finger Both 7 17 14 musculoskeletal darkolivegreen 17, 7 5, 1 4, 1 4, 3 4, 2 0.033 0.542 0.951 0.022 1.03 0.392 3.2 0.448 2.98 0.88 0.055 1.56 0.0113 9800 2.12 2.04 0.298 0.525 8.35 0.613 9.88 1.15 2.48 0.644 0.191 3.15 0.00248 5810 PRS_PLINK_0.000199526231496888 TRUE 736.3 Acquired deformities of hip Both 1 12 14 musculoskeletal darkolivegreen 12, 1 3, 0 3, 0 3, 0 3, 1 0.355 0.689 0.606 0.217 1.43 0.494 7.74 0.0122 775 1 0 1.01 0.714 2.68 PRS_PLINK_0.000199526231496888 TRUE 736.4 Genu valgum or varum (acquired) Both 1 20 14 musculoskeletal darkolivegreen 20, 1 5, 0 5, 0 5, 0 5, 1 0.198 0.794 0.803 0.096 1.22 0.0711 12 0.112 1.99 0.955 0.02 1.12 0.0136 119 PRS_PLINK_0.000199526231496888 TRUE 736.5 Acquired deformities of knee Both 0 11 14 musculoskeletal darkolivegreen 11, 0 3 3 2 3 PRS_PLINK_0.000199526231496888 TRUE 736.6 Unequal leg length (acquired) Both 8 24 14 musculoskeletal darkolivegreen 24, 8 6, 2 6, 5 6, 0 6, 1 -0.198 0.554 0.721 0.142 0.821 0.233 2.24 0.816 1.91 0.67 0.174 2.26 0.00984 162 -1.29 2.27 0.569 0.245 0.275 4.91e-08 11.6 2.55 3.51 0.467 0.33 12.8 0.0307 16.2 PRS_PLINK_0.000199526231496888 TRUE 737 Curvature of spine Both 18 128 14 musculoskeletal darkolivegreen 128, 18 32, 5 32, 3 32, 5 32, 5 -0.372 0.301 0.217 0.664 0.689 0.372 1.25 -0.392 0.786 0.617 0.209 0.675 0.12 3.31 -0.561 0.72 0.436 0.361 0.57 0.12 2.33 -0.823 0.842 0.328 0.484 0.439 0.0743 2.1 PRS_PLINK_0.000199526231496888 TRUE 737.1 Kyphosis (acquired) Both 2 33 14 musculoskeletal darkolivegreen 33, 2 9, 1 8, 0 8, 0 8, 1 0.0133 0.582 0.982 0.008 1.01 0.17 8.67 -1.25 2.27 0.582 0.235 0.286 5.56e-11 9.43 -0.424 1.49 0.775 0.111 0.654 1.6e-05 28.6 -0.134 1.79 0.941 0.027 0.875 1.01e-05 46.5 PRS_PLINK_0.000199526231496888 TRUE 737.2 Lordosis (acquired) Both 0 1 14 musculoskeletal darkolivegreen 1, 0 PRS_PLINK_0.000199526231496888 TRUE 737.3 Kyphoscoliosis and scoliosis Both 17 99 14 musculoskeletal darkolivegreen 99, 17 24, 5 25, 2 24, 6 25, 4 -0.36 0.289 0.212 0.674 0.698 0.389 1.22 -0.759 0.893 0.396 0.403 0.468 0.0587 2.53 0.0354 0.779 0.964 0.016 1.04 0.217 4.94 -1.22 0.923 0.186 0.731 0.295 0.041 1.57 PRS_PLINK_0.000199526231496888 TRUE 738 Other acquired musculoskeletal deformity Both 20 186 14 musculoskeletal darkolivegreen 186, 20 47, 5 46, 5 46, 6 47, 4 0.133 0.262 0.612 0.213 1.14 0.674 1.95 0.36 0.749 0.63 0.2 1.43 0.317 6.87 0.351 0.671 0.601 0.221 1.42 0.374 5.85 0.0237 0.791 0.976 0.01 1.02 0.193 5.2 PRS_PLINK_0.000199526231496888 TRUE 738.4 Acquired spondylolisthesis Both 10 65 14 musculoskeletal darkolivegreen 65, 10 17, 2 16, 5 16, 1 16, 2 -0.0187 0.525 0.972 0.013 0.981 0.314 3.11 -1.85 1.81 0.307 0.512 0.158 0.00038 6.76 -0.965 1.28 0.451 0.346 0.381 0.0171 5.18 0.271 1.24 0.827 0.083 1.31 0.0813 23.4 PRS_PLINK_0.000199526231496888 TRUE 739 Contracture of joint Both 9 55 14 musculoskeletal darkolivegreen 55, 9 14, 1 14, 1 13, 5 14, 2 0.296 0.424 0.485 0.314 1.34 0.601 3.28 0.108 1.11 0.923 0.035 1.11 0.1 16.7 0.962 1.06 0.363 0.44 2.62 0.378 24.9 1.43 1.6 0.372 0.43 4.18 0.145 2240 PRS_PLINK_0.000199526231496888 TRUE 740 Osteoarthrosis Both 147 306 14 musculoskeletal darkolivegreen 306, 147 76, 40 76, 44 76, 27 77, 36 -0.0807 0.116 0.488 0.312 0.922 0.735 1.16 0.262 0.31 0.398 0.4 1.3 0.713 2.39 -0.488 0.352 0.166 0.781 0.614 0.306 1.21 -0.12 0.326 0.712 0.148 0.886 0.471 1.66 PRS_PLINK_0.000199526231496888 FALSE 740.1 Osteoarthritis; localized Both 77 243 14 musculoskeletal darkolivegreen 243, 77 60, 21 61, 20 60, 19 61, 17 -0.121 0.155 0.436 0.361 0.886 0.654 1.2 0.011 0.447 0.98 0.009 1.01 0.42 2.44 -0.291 0.475 0.54 0.268 0.747 0.292 1.86 -0.288 0.447 0.52 0.284 0.75 0.314 1.76 PRS_PLINK_0.000199526231496888 FALSE 740.11 Osteoarthrosis, localized, primary Both 69 219 14 musculoskeletal darkolivegreen 219, 69 54, 19 55, 16 54, 17 55, 17 -0.0551 0.163 0.736 0.133 0.946 0.688 1.3 -0.0694 0.504 0.89 0.05 0.933 0.343 2.54 -0.329 0.506 0.516 0.287 0.72 0.262 1.9 -0.156 0.458 0.733 0.135 0.855 0.353 2.06 PRS_PLINK_0.000199526231496888 FALSE 740.12 Osteoarthrosis, localized, secondary Both 6 52 14 musculoskeletal darkolivegreen 52, 6 13, 1 13, 1 13, 2 13, 2 -0.0702 0.429 0.87 0.06 0.932 0.394 2.6 -0.0268 1.33 0.984 0.007 0.974 0.0328 24.9 0.292 1.15 0.8 0.097 1.34 0.0859 95.9 0.586 1.22 0.631 0.2 1.8 0.12 30.3 PRS_PLINK_0.000199526231496888 TRUE 740.2 Osteoarthrosis, generalized Both 28 61 14 musculoskeletal darkolivegreen 61, 28 16, 12 15, 8 15, 6 15, 2 -0.494 0.299 0.0985 1.006 0.61 0.331 1.05 -0.252 0.735 0.732 0.136 0.777 0.187 3.17 -0.661 0.843 0.433 0.364 0.516 0.0909 2.65 -1.04 0.993 0.293 0.533 0.352 0.0411 2.13 PRS_PLINK_0.000199526231496888 TRUE 740.3 Osteoarthrosis involving more than one site, but not specified as generalized Both 6 21 14 musculoskeletal darkolivegreen 21, 6 6, 4 5, 0 5, 1 5, 1 -0.357 0.508 0.482 0.317 0.7 0.241 1.64 -1 1.81 0.58 0.237 0.368 0.00417 5.92 -1.7 2.06 0.411 0.386 0.183 0.000132 3.59 0.0971 1.53 0.949 0.023 1.1 0.904 1.18 PRS_PLINK_0.000199526231496888 TRUE 740.9 Osteoarthrosis NOS Both 143 306 14 musculoskeletal darkolivegreen 306, 143 76, 39 76, 44 76, 25 77, 35 -0.0988 0.117 0.399 0.399 0.906 0.721 1.14 0.294 0.312 0.347 0.46 1.34 0.733 2.47 -0.527 0.359 0.142 0.848 0.591 0.291 1.17 -0.112 0.329 0.733 0.135 0.894 0.472 1.69 PRS_PLINK_0.000199526231496888 FALSE 741 Symptoms and disorders of the joints Both 107 300 14 musculoskeletal darkolivegreen 300, 107 74, 20 75, 25 75, 30 75, 32 0.157 0.125 0.208 0.682 1.17 0.92 1.49 0.456 0.377 0.227 0.644 1.58 0.764 3.33 0.229 0.365 0.53 0.276 1.26 0.624 2.56 0.522 0.369 0.157 0.805 1.69 0.834 3.49 PRS_PLINK_0.000199526231496888 FALSE 741.1 Ankylosis of joint Both 2 23 14 musculoskeletal darkolivegreen 23, 2 6, 1 6, 0 5, 0 6, 1 -0.234 0.688 0.734 0.134 0.791 0.0521 5.03 -0.529 2.23 0.813 0.09 0.589 0.00251 103 -0.153 1.99 0.939 0.027 0.858 0.00497 24.6 -1.42 1.72 0.407 0.39 0.241 0.000179 4.03 PRS_PLINK_0.000199526231496888 TRUE 741.2 Stiffness of joint Both 18 105 14 musculoskeletal darkolivegreen 105, 18 27, 3 26, 4 26, 6 26, 5 -0.0683 0.262 0.794 0.1 0.934 0.554 1.57 0.575 0.855 0.501 0.3 1.78 0.321 10 0.659 0.766 0.39 0.409 1.93 0.431 10.1 0.187 0.774 0.809 0.092 1.21 0.257 6.17 PRS_PLINK_0.000199526231496888 TRUE 741.3 Difficulty in walking Both 24 108 14 musculoskeletal darkolivegreen 108, 24 27, 6 27, 5 27, 3 27, 10 0.268 0.251 0.287 0.542 1.31 0.816 2.14 0.253 0.784 0.747 0.127 1.29 0.284 6.5 -0.535 1.01 0.595 0.226 0.586 0.0542 4.38 0.459 0.673 0.495 0.305 1.58 0.454 5.85 PRS_PLINK_0.000199526231496888 TRUE 741.4 Joint effusions Both 40 197 14 musculoskeletal darkolivegreen 197, 40 49, 10 49, 8 49, 12 49, 10 0.119 0.186 0.524 0.281 1.13 0.783 1.63 0.126 0.543 0.816 0.088 1.13 0.391 3.3 0.052 0.52 0.92 0.036 1.05 0.38 2.9 0.294 0.539 0.585 0.233 1.34 0.472 3.89 PRS_PLINK_0.000199526231496888 TRUE 741.5 Hemarthrosis Both 1 5 14 musculoskeletal darkolivegreen 5, 1 1, 0 1, 1 1, 0 1, 0 0.137 467 1 0 1.15 0.832 1.34 0.0456 439 1 0 1.05 0.868 1.53 PRS_PLINK_0.000199526231496888 TRUE 741.6 Villonodular synovitis Both 0 5 14 musculoskeletal darkolivegreen 5, 0 2 1 1 1 PRS_PLINK_0.000199526231496888 TRUE 742 Derangement of joint, non-traumatic Both 83 294 14 musculoskeletal darkolivegreen 294, 83 73, 18 73, 20 73, 16 74, 29 0.153 0.132 0.245 0.61 1.17 0.902 1.51 0.108 0.397 0.785 0.105 1.11 0.516 2.42 -0.298 0.417 0.475 0.324 0.742 0.326 1.66 0.543 0.372 0.145 0.839 1.72 0.844 3.6 PRS_PLINK_0.000199526231496888 FALSE 742.1 Loose body in joint Both 1 10 14 musculoskeletal darkolivegreen 10, 1 3, 0 2, 0 2, 1 3, 0 0.0202 1.07 0.985 0.007 1.02 0.104 7.67 -4.86 21200000 1 0 0.00779 6.98e-14 2.22e+11 PRS_PLINK_0.000199526231496888 TRUE 742.2 Pathological, developmental or recurrent dislocation Both 1 32 14 musculoskeletal darkolivegreen 32, 1 8, 0 8, 0 8, 0 8, 1 0.014 0.761 0.985 0.006 1.01 0.0832 8.44 -0.301 2.65 0.909 0.041 0.74 0.000183 685 PRS_PLINK_0.000199526231496888 TRUE 742.8 Articular cartilage disorder Both 3 28 14 musculoskeletal darkolivegreen 28, 3 7, 1 7, 1 7, 1 7, 0 -0.0292 0.693 0.966 0.015 0.971 0.225 4.34 0.359 1.7 0.833 0.08 1.43 0.0639 44100 0.423 1.76 0.81 0.092 1.53 0.00167 131 -0.446 2.02 0.825 0.083 0.64 0.0126 68.2 PRS_PLINK_0.000199526231496888 TRUE 742.9 Other derangement of joint Both 83 292 14 musculoskeletal darkolivegreen 292, 83 72, 18 73, 20 73, 16 73, 29 0.155 0.132 0.239 0.621 1.17 0.904 1.52 0.105 0.397 0.791 0.102 1.11 0.515 2.41 -0.302 0.416 0.468 0.33 0.739 0.325 1.65 0.573 0.376 0.127 0.896 1.77 0.865 3.74 PRS_PLINK_0.000199526231496888 FALSE 743 Osteoporosis, osteopenia and pathological fracture Both 104 340 14 musculoskeletal darkolivegreen 340, 104 84, 28 85, 21 85, 30 85, 25 -0.0344 0.128 0.788 0.103 0.966 0.752 1.24 -0.158 0.375 0.673 0.172 0.854 0.409 1.77 0.121 0.371 0.745 0.128 1.13 0.547 2.34 0.0378 0.373 0.919 0.036 1.04 0.504 2.15 PRS_PLINK_0.000199526231496888 FALSE 743.1 Osteoporosis Both 37 142 14 musculoskeletal darkolivegreen 142, 37 36, 12 35, 6 35, 15 36, 4 -0.314 0.235 0.182 0.739 0.731 0.455 1.15 -0.453 0.705 0.521 0.283 0.636 0.156 2.47 0.483 0.621 0.437 0.36 1.62 0.488 5.77 -1.11 0.845 0.188 0.726 0.329 0.051 1.67 PRS_PLINK_0.000199526231496888 TRUE 743.11 Osteoporosis NOS Both 34 142 14 musculoskeletal darkolivegreen 142, 34 36, 12 35, 5 35, 14 36, 3 -0.374 0.242 0.122 0.913 0.688 0.42 1.1 -0.522 0.706 0.46 0.337 0.594 0.146 2.3 0.448 0.62 0.47 0.328 1.56 0.473 5.54 -1.89 1.03 0.0655 1.184 0.151 0.0124 0.991 PRS_PLINK_0.000199526231496888 TRUE 743.12 Senile osteoporosis Both 8 17 14 musculoskeletal darkolivegreen 17, 8 5, 3 4, 1 4, 4 4, 0 -0.0814 0.57 0.886 0.052 0.922 0.296 2.59 0.8 2.55 0.754 0.123 2.22 0.000354 881 1.1 1.7 0.517 0.286 3.01 0.00513 771 -0.597 2.27 0.793 0.101 0.551 0.00508 56.5 PRS_PLINK_0.000199526231496888 TRUE 743.13 Other specified osteoporosis Both 6 12 14 musculoskeletal darkolivegreen 12, 6 3, 0 3, 1 3, 5 3, 0 0.592 0.831 0.476 0.323 1.81 0.33 143 -0.228 1580 1 0 0.796 0.0908 1.53 -0.945 14.4 0.948 0.023 0.389 0.361 0.421 PRS_PLINK_0.000199526231496888 TRUE 743.2 Pathologic fracture Both 8 50 14 musculoskeletal darkolivegreen 50, 8 13, 2 12, 1 12, 3 13, 2 -0.048 0.391 0.902 0.045 0.953 0.433 2.23 0.174 1.38 0.9 0.046 1.19 0.0753 124 0.105 1.03 0.919 0.037 1.11 0.162 9.15 0.678 1.18 0.565 0.248 1.97 0.2 31.5 PRS_PLINK_0.000199526231496888 TRUE 743.21 Pathologic fracture of vertebrae Both 4 20 14 musculoskeletal darkolivegreen 20, 4 5, 2 5, 0 5, 1 5, 1 0.251 0.65 0.7 0.155 1.28 0.402 10.7 -2.7 3.18 0.397 0.402 0.0673 3.33e-06 7.54 -0.342 1.68 0.838 0.076 0.71 0.00254 32.6 1.48 1.93 0.444 0.352 4.39 0.237 3170 PRS_PLINK_0.000199526231496888 TRUE 743.22 Pathologic fracture of femur Both 1 9 14 musculoskeletal darkolivegreen 9, 1 3, 0 2, 1 2, 0 2, 0 -2.69 4.88 0.582 0.235 0.0679 1.27e-06 70.6 0.0564 1760000 1 0 1.06 0.405 2.69 PRS_PLINK_0.000199526231496888 TRUE 743.4 Stress fracture Both 6 41 14 musculoskeletal darkolivegreen 41, 6 11, 2 10, 2 10, 0 10, 2 -0.147 0.5 0.769 0.114 0.863 0.319 2.24 0.918 1.56 0.555 0.256 2.5 0.0245 420 0.464 1.62 0.775 0.111 1.59 0.000973 9770 1.05 1.65 0.525 0.28 2.85 0.09 278 PRS_PLINK_0.000199526231496888 TRUE 743.9 Osteopenia or other disorder of bone and cartilage Both 92 308 14 musculoskeletal darkolivegreen 308, 92 76, 24 77, 19 77, 26 77, 23 -0.0155 0.132 0.906 0.043 0.985 0.761 1.27 -0.0759 0.386 0.844 0.074 0.927 0.436 1.97 0.167 0.37 0.652 0.186 1.18 0.577 2.44 0.0168 0.388 0.966 0.015 1.02 0.477 2.16 PRS_PLINK_0.000199526231496888 FALSE 745 Pain in joint Both 289 164 14 musculoskeletal darkolivegreen 164, 289 40, 64 41, 65 41, 67 41, 93 0.138 0.108 0.203 0.692 1.15 0.931 1.42 0.119 0.311 0.702 0.154 1.13 0.619 2.06 -0.127 0.316 0.689 0.162 0.881 0.474 1.62 0.177 0.31 0.569 0.245 1.19 0.653 2.18 PRS_PLINK_0.000199526231496888 FALSE 747 Cardiac and circulatory congenital anomalies Both 29 200 15 congenital anomalies mediumspringgreen 200, 29 49, 1 50, 7 50, 9 50, 12 0.454 0.205 0.0264 1.578 1.58 1.05 2.41 1.28 0.808 0.114 0.945 3.59 0.747 32.3 1.49 0.814 0.0675 1.171 4.43 0.946 40.4 1.92 0.8 0.0162 1.791 6.84 1.56 63.7 PRS_PLINK_0.000199526231496888 TRUE 747.1 Cardiac congenital anomalies Both 21 151 15 congenital anomalies mediumspringgreen 151, 21 38, 0 38, 7 37, 6 38, 8 0.504 0.243 0.0377 1.423 1.66 1.03 2.77 2.28 1.18 0.0521 1.283 9.82 1.18 1200 2.12 1.11 0.0559 1.253 8.34 1.07 821 2.65 1.19 0.026 1.584 14.2 1.75 1770 PRS_PLINK_0.000199526231496888 TRUE 747.11 Cardiac shunt/ heart septal defect Both 9 64 15 congenital anomalies mediumspringgreen 64, 9 16, 2 16, 3 16, 0 16, 4 0.394 0.435 0.365 0.437 1.48 0.623 3.65 0.404 1.09 0.712 0.148 1.5 0.169 14 -0.83 1.51 0.582 0.235 0.436 0.00035 16.9 0.996 1.21 0.41 0.387 2.71 0.309 48.6 PRS_PLINK_0.000199526231496888 TRUE 747.12 Valvular heart disease/ heart chambers Both 6 36 15 congenital anomalies mediumspringgreen 36, 6 9, 0 9, 1 9, 3 9, 2 1.32 0.653 0.0436 1.361 3.74 1.16 18.6 0.855 1.86 0.646 0.19 2.35 0.0116 3260 0.811 1.55 0.601 0.221 2.25 0.161 138 2.78 2.43 0.253 0.597 16.1 0.393 1180000 PRS_PLINK_0.000199526231496888 TRUE 747.13 Congenital anomalies of great vessels Both 4 39 15 congenital anomalies mediumspringgreen 39, 4 10, 0 10, 1 9, 1 10, 2 1.18 0.691 0.087 1.061 3.26 1 41.6 0.69 1.99 0.729 0.138 1.99 0.00122 2090 -0.185 1.88 0.922 0.035 0.831 0.000394 241 1.02 1.61 0.526 0.279 2.77 0.226 1830 PRS_PLINK_0.000199526231496888 TRUE 747.2 Congenital anomalies of peripheral vascular system Both 8 70 15 congenital anomalies mediumspringgreen 70, 8 17, 1 17, 3 17, 0 18, 4 0.332 0.436 0.447 0.35 1.39 0.579 3.79 0.585 1.18 0.619 0.208 1.79 0.159 31.6 -1.07 1.36 0.435 0.362 0.344 0.00273 6.41 1.04 1.24 0.405 0.393 2.82 0.0403 122 PRS_PLINK_0.000199526231496888 TRUE 748 Anomalies of respiratory system, congenital Both 1 12 15 congenital anomalies mediumspringgreen 12, 1 3, 0 3, 0 3, 0 3, 1 -0.201 0.92 0.827 0.082 0.818 0.000145 9.31 -0.0965 2730 1 0 0.908 0.28 3.11 PRS_PLINK_0.000199526231496888 TRUE 749 Congenital anomalies of face and neck Both 3 63 15 congenital anomalies mediumspringgreen 63, 3 16, 1 16, 1 15, 1 16, 0 -0.223 0.638 0.726 0.139 0.8 0.167 4.73 -0.774 1.32 0.558 0.254 0.461 0.0136 7.71 -0.259 1.12 0.818 0.087 0.772 0.0319 11.5 -0.0573 1.5 0.97 0.013 0.944 0.0262 153 PRS_PLINK_0.000199526231496888 TRUE 749.1 Cleft palate Both 0 9 15 congenital anomalies mediumspringgreen 9, 0 3 2 2 2 PRS_PLINK_0.000199526231496888 TRUE 749.2 Congenital anomalies of skull and face bones Both 3 21 15 congenital anomalies mediumspringgreen 21, 3 6, 1 5, 1 5, 1 5, 0 -0.0912 1.2 0.939 0.027 0.913 0.0242 62.9 -0.3 2.42 0.901 0.045 0.741 0.00153 45.9 -1.17 2.57 0.65 0.187 0.311 1.08e-05 83.3 0.935 3.27 0.775 0.111 2.55 0.00346 1130000 PRS_PLINK_0.000199526231496888 TRUE 750 Digestive congenital anomalies Both 17 68 15 congenital anomalies mediumspringgreen 68, 17 17, 9 17, 1 17, 6 17, 1 -0.341 0.302 0.259 0.587 0.711 0.385 1.25 -1.7 0.914 0.0631 1.2 0.183 0.0184 0.914 -0.121 0.744 0.871 0.06 0.886 0.214 3.52 -1.67 0.964 0.0836 1.078 0.188 0.0181 1.01 PRS_PLINK_0.000199526231496888 TRUE 750.1 Upper gastrointestinal congenital anomalies Both 3 20 15 congenital anomalies mediumspringgreen 20, 3 5, 0 5, 0 5, 1 5, 2 0.784 0.746 0.293 0.533 2.19 0.659 19.6 0.208 2.89 0.942 0.026 1.23 0.00371 283 0.0423 1.87 0.982 0.008 1.04 0.0132 30.9 PRS_PLINK_0.000199526231496888 TRUE 750.11 Esophageal atresia/tracheoesophageal fistula Both 1 7 15 congenital anomalies mediumspringgreen 7, 1 2, 0 2, 0 1, 0 2, 1 -0.00174 22.5 1 0 0.998 0.886 1.38 1.16e-05 107 1 0 1 0.541 1.74 PRS_PLINK_0.000199526231496888 TRUE 750.13 Congenital anomalies of mouth/tongue Both 0 10 15 congenital anomalies mediumspringgreen 10, 0 3 2 2 3 PRS_PLINK_0.000199526231496888 TRUE 750.14 Congenital anomalies of esophagus Both 0 14 15 congenital anomalies mediumspringgreen 14, 0 4 3 3 4 PRS_PLINK_0.000199526231496888 TRUE 750.15 Congenital anomalies of stomach Both 0 2 15 congenital anomalies mediumspringgreen 2, 0 1 1 1 1 PRS_PLINK_0.000199526231496888 TRUE 750.2 Lower gastrointestinal congenital anomalies Both 14 41 15 congenital anomalies mediumspringgreen 41, 14 11, 9 10, 1 10, 4 10, 0 -0.777 0.436 0.075 1.125 0.46 0.169 0.992 -1.46 1.01 0.146 0.835 0.232 0.023 1.27 -0.355 0.947 0.708 0.15 0.701 0.117 3.87 -2.57 1.46 0.0781 1.107 0.0766 0.000659 0.776 PRS_PLINK_0.000199526231496888 TRUE 750.21 Congenital anomalies of intestine Both 10 31 15 congenital anomalies mediumspringgreen 31, 10 8, 7 8, 1 7, 0 8, 2 -0.551 0.495 0.265 0.576 0.576 0.188 1.42 -1.43 1.32 0.279 0.554 0.24 0.00783 2.14 -3.81 2.76 0.167 0.778 0.0221 1.51e-05 1.7 -0.548 1.52 0.718 0.144 0.578 0.00981 17.1 PRS_PLINK_0.000199526231496888 TRUE 750.22 Congenital anomaly of gallbladder, bile ducts, liver, pancreas Both 5 15 15 congenital anomalies mediumspringgreen 15, 5 4, 3 4, 1 3, 1 4, 0 -0.756 0.803 0.346 0.46 0.47 0.0748 1.78 -0.482 2.06 0.815 0.089 0.618 0.0269 15 0.065 1.77 0.971 0.013 1.07 0.0526 143 -4.36 5.61 0.437 0.36 0.0128 4.3e-10 37.2 PRS_PLINK_0.000199526231496888 TRUE 751 Genitourinary congenital anomalies Both 51 196 15 congenital anomalies mediumspringgreen 196, 51 49, 11 49, 23 49, 6 49, 11 -0.106 0.161 0.512 0.291 0.9 0.655 1.23 0.731 0.443 0.0992 1.004 2.08 0.908 4.99 -0.553 0.545 0.31 0.508 0.575 0.184 1.65 0.0632 0.487 0.897 0.047 1.07 0.412 2.77 PRS_PLINK_0.000199526231496888 FALSE 751.1 Congenital anomalies of genital organs Both 22 82 15 congenital anomalies mediumspringgreen 82, 22 21, 9 20, 8 20, 2 21, 3 -0.378 0.255 0.139 0.858 0.686 0.404 1.11 0.612 0.727 0.4 0.398 1.84 0.482 7.84 -1.01 0.792 0.203 0.692 0.365 0.0587 1.53 -0.33 0.821 0.687 0.163 0.719 0.14 3.32 PRS_PLINK_0.000199526231496888 TRUE 751.11 Congenital anomalies of female genital organs Female 21 75 15 congenital anomalies mediumspringgreen 75, 21 19, 9 19, 8 18, 1 19, 3 -0.428 0.257 0.0962 1.017 0.652 0.383 1.05 0.282 0.668 0.673 0.172 1.33 0.386 4.7 -1.56 0.951 0.1 0.999 0.21 0.0166 1.11 -0.407 0.832 0.625 0.204 0.666 0.125 3.13 PRS_PLINK_0.000199526231496888 TRUE 751.12 Congenital anomalies of male genital organs Male 0 5 15 congenital anomalies mediumspringgreen 5, 0 2 1 1 1 PRS_PLINK_0.000199526231496888 TRUE 751.2 Congenital anomalies of urinary system Both 30 117 15 congenital anomalies mediumspringgreen 117, 30 30, 6 29, 11 29, 4 29, 9 -0.000821 0.21 0.997 0.001 0.999 0.663 1.51 0.469 0.633 0.459 0.338 1.6 0.479 5.61 -0.559 0.685 0.415 0.382 0.572 0.141 2.09 0.625 0.655 0.34 0.469 1.87 0.545 7.2 PRS_PLINK_0.000199526231496888 TRUE 751.21 Cystic kidney disease Both 20 76 15 congenital anomalies mediumspringgreen 76, 20 19, 4 19, 9 19, 3 19, 4 -0.165 0.254 0.516 0.287 0.848 0.513 1.39 0.475 0.775 0.54 0.268 1.61 0.377 7.57 -0.848 0.908 0.351 0.455 0.428 0.0616 2.27 0.0938 0.869 0.914 0.039 1.1 0.19 6.14 PRS_PLINK_0.000199526231496888 TRUE 751.22 Other specified congenital anomalies of kidney Both 6 20 15 congenital anomalies mediumspringgreen 20, 6 5, 1 5, 1 5, 1 5, 3 0.336 0.715 0.638 0.195 1.4 0.0314 1.94 -0.398 1.76 0.821 0.085 0.672 0.0175 24.2 0.862 1.9 0.649 0.187 2.37 0.15 80.7 1.14 2.06 0.579 0.237 3.14 0.114 1690 PRS_PLINK_0.000199526231496888 TRUE 751.3 Obstructive genitourinary defect Both 4 17 15 congenital anomalies mediumspringgreen 17, 4 5, 0 4, 2 4, 1 4, 1 0.77 1.29 0.552 0.258 2.16 0.0785 614 -0.115 3.38 0.973 0.012 0.891 0.0286 29.1 1.49 1020 0.999 0.001 4.42 3.86 5.04 2.88 16.8 0.864 0.064 17.9 9.85e-10 1.59e+12 PRS_PLINK_0.000199526231496888 TRUE 752 Nervous system congenital anomalies Both 15 113 15 congenital anomalies mediumspringgreen 113, 15 29, 4 28, 3 28, 5 28, 3 0.134 0.286 0.638 0.195 1.14 0.65 2.1 -0.516 0.802 0.52 0.284 0.597 0.105 2.86 -0.394 0.806 0.625 0.204 0.675 0.116 3.32 -0.12 0.848 0.888 0.052 0.887 0.137 5.09 PRS_PLINK_0.000199526231496888 TRUE 752.1 Neural tube defects Both 10 80 15 congenital anomalies mediumspringgreen 80, 10 20, 1 20, 5 20, 2 20, 2 0.022 0.336 0.948 0.023 1.02 0.512 2.08 0.937 1.1 0.393 0.406 2.55 0.295 44.1 0.0305 1.08 0.977 0.01 1.03 0.0838 11.6 0.998 1.26 0.427 0.37 2.71 0.0645 85.3 PRS_PLINK_0.000199526231496888 TRUE 752.11 Spina bifida Both 5 35 15 congenital anomalies mediumspringgreen 35, 5 8, 1 9, 1 8, 2 9, 1 -0.236 0.463 0.61 0.215 0.79 0.199 1.84 -0.194 1.56 0.901 0.045 0.823 2.38e-06 14.4 -0.593 1.53 0.699 0.155 0.553 0.0111 17.1 -0.275 2.21 0.901 0.045 0.759 1.7e-05 47.5 PRS_PLINK_0.000199526231496888 TRUE 752.2 Other specified congenital anomalies of nervous system Both 3 31 15 congenital anomalies mediumspringgreen 31, 3 8, 0 8, 1 7, 0 8, 2 -0.239 0.677 0.724 0.14 0.787 0.00182 4.01 0.75 2.51 0.765 0.116 2.12 4.14e-05 820 0.418 2 0.835 0.079 1.52 0.0229 5340 PRS_PLINK_0.000199526231496888 TRUE 753 Congenital anomalies of the eye Both 2 18 15 congenital anomalies mediumspringgreen 18, 2 5, 0 4, 0 4, 0 5, 2 0.184 0.959 0.848 0.072 1.2 0.137 93.9 0.636 2.1 0.762 0.118 1.89 0.0731 60.4 PRS_PLINK_0.000199526231496888 TRUE 753.1 Congenital cataract and lens anomalies Both 0 5 15 congenital anomalies mediumspringgreen 5, 0 2 1 1 1 PRS_PLINK_0.000199526231496888 TRUE 753.2 Congenital anomalies of posterior segment of eye Both 1 2 15 congenital anomalies mediumspringgreen 2, 1 1, 1 1, 0 1, 1 1, 0 -0.0189 258 1 0 0.981 0.771 1.11 -0.107 908 1 0 0.898 0.385 1.27 PRS_PLINK_0.000199526231496888 TRUE 754 Congenital musculoskeletal deformities of spine Both 11 88 15 congenital anomalies mediumspringgreen 88, 11 22, 2 22, 6 22, 2 22, 1 -0.305 0.416 0.464 0.333 0.737 0.297 1.77 -0.852 1.22 0.484 0.315 0.427 0.0126 5.11 -0.485 1.15 0.674 0.172 0.616 0.0505 5.76 -0.138 1.21 0.909 0.041 0.871 0.0232 15.5 PRS_PLINK_0.000199526231496888 TRUE 754.1 Lumbosacral spondylolysis, congenital Both 0 11 15 congenital anomalies mediumspringgreen 11, 0 3 3 2 3 PRS_PLINK_0.000199526231496888 TRUE 754.2 Spondylolisthesis, congenital Both 7 48 15 congenital anomalies mediumspringgreen 48, 7 12, 1 12, 3 12, 3 12, 0 -0.176 0.555 0.751 0.124 0.839 0.221 3.09 -0.395 1.74 0.82 0.086 0.674 0.00153 541 0.481 1.56 0.758 0.121 1.62 0.0642 94.2 -0.133 1.52 0.931 0.031 0.876 0.0117 75.1 PRS_PLINK_0.000199526231496888 TRUE 755 Congenital anomalies of limbs Both 16 91 15 congenital anomalies mediumspringgreen 91, 16 23, 8 23, 3 22, 1 23, 4 -0.632 0.344 0.0658 1.182 0.531 0.26 1.03 -0.616 0.741 0.405 0.392 0.54 0.118 2.16 -2.53 1.29 0.0492 1.308 0.0797 0.000649 0.647 -0.525 0.761 0.49 0.31 0.591 0.124 2.52 PRS_PLINK_0.000199526231496888 TRUE 755.1 Congenital deformities of feet Both 10 31 15 congenital anomalies mediumspringgreen 31, 10 7, 2 8, 3 7, 2 8, 3 0.227 0.533 0.671 0.173 1.25 0.457 3.9 -0.775 1.66 0.64 0.194 0.461 6.54e-07 8.33 0.666 1.9 0.726 0.139 1.95 0.0137 524 -0.902 1.99 0.65 0.187 0.406 0.000499 78.2 PRS_PLINK_0.000199526231496888 TRUE 755.4 Congenital anomalies of upper limb, including shoulder girdle Both 0 9 15 congenital anomalies mediumspringgreen 9, 0 3 2 2 2 PRS_PLINK_0.000199526231496888 TRUE 755.6 Other congenital anomalies of lower limb, including pelvic girdle Both 6 45 15 congenital anomalies mediumspringgreen 45, 6 12, 4 11, 1 11, 0 11, 1 -0.651 0.474 0.17 0.77 0.522 0.195 1.33 -0.472 1.13 0.676 0.17 0.624 0.0617 4.87 -2.13 1.49 0.152 0.818 0.119 0.000798 1.31 -0.658 1.62 0.684 0.165 0.518 0.0244 259 PRS_PLINK_0.000199526231496888 TRUE 755.61 Congenital hip dysplasia and deformity Both 2 34 15 congenital anomalies mediumspringgreen 34, 2 9, 1 8, 0 8, 0 9, 1 0.565 0.749 0.45 0.347 1.76 0.242 67.2 -0.0514 1.53 0.973 0.012 0.95 0.0162 38.2 0.104 1.58 0.948 0.023 1.11 0.0128 226 0.292 1.55 0.85 0.07 1.34 0.00461 115 PRS_PLINK_0.000199526231496888 TRUE 756 Other congenital musculoskeletal anomalies Both 17 138 15 congenital anomalies mediumspringgreen 138, 17 34, 4 34, 3 34, 4 35, 6 0.345 0.308 0.262 0.582 1.41 0.775 2.73 -0.434 0.932 0.642 0.193 0.648 0.0687 5.05 0.473 0.803 0.556 0.255 1.6 0.337 9.25 2.24 1.47 0.128 0.893 9.43 0.786 1520 PRS_PLINK_0.000199526231496888 TRUE 756.1 Congenital anomalies of abdominal wall; diaphram Both 0 11 15 congenital anomalies mediumspringgreen 11, 0 3 3 2 3 PRS_PLINK_0.000199526231496888 TRUE 756.2 Pectus and other congenital anomalies of ribs/sternum Both 0 6 15 congenital anomalies mediumspringgreen 6, 0 2 1 1 2 PRS_PLINK_0.000199526231496888 TRUE 756.3 Congenital anomalies of muscle, tendon, fascia, and connective tissue Both 2 36 15 congenital anomalies mediumspringgreen 36, 2 9, 0 9, 0 9, 0 9, 2 0.316 0.681 0.643 0.192 1.37 0.0721 126 1.2 1.64 0.465 0.332 3.31 0.221 370 PRS_PLINK_0.000199526231496888 TRUE 756.5 Congenital osteodystrophies Both 12 82 15 congenital anomalies mediumspringgreen 82, 12 20, 3 20, 2 20, 4 21, 3 0.24 0.319 0.452 0.345 1.27 0.687 2.49 0.0932 1.06 0.93 0.031 1.1 0.115 11.8 0.923 0.988 0.35 0.455 2.52 0.429 24.5 1.04 1.43 0.469 0.329 2.83 0.162 155 PRS_PLINK_0.000199526231496888 TRUE 757 Congenital anomalies of the integument Both 7 30 15 congenital anomalies mediumspringgreen 30, 7 8, 0 7, 2 7, 2 8, 3 0.595 0.483 0.218 0.661 1.81 0.789 7.75 1.11 1.96 0.57 0.244 3.04 0.00747 740 0.517 1.87 0.782 0.107 1.68 0.0169 129 1.96 1.56 0.21 0.677 7.1 0.595 770 PRS_PLINK_0.000199526231496888 TRUE 758 Chromosomal anomalies and genetic disorders Both 4 29 15 congenital anomalies mediumspringgreen 29, 4 7, 0 7, 2 7, 1 7, 1 0.261 0.519 0.615 0.211 1.3 0.512 4.8 0.654 2.08 0.753 0.123 1.92 0.0658 135000 1.12 2.49 0.653 0.185 3.06 0.0251 4880 0.218 2.45 0.929 0.032 1.24 0.00289 298 PRS_PLINK_0.000199526231496888 TRUE 758.1 Chromosomal anomalies Both 4 23 15 congenital anomalies mediumspringgreen 23, 4 5, 0 6, 2 5, 0 6, 2 0.218 0.513 0.67 0.174 1.24 0.535 4.53 -1.11 2.85 0.697 0.157 0.33 6.87e-05 87.6 2.83 3.01 0.347 0.46 16.9 0.133 332000 PRS_PLINK_0.000199526231496888 TRUE 759 Other and unspecified congenital anomalies Both 19 83 15 congenital anomalies mediumspringgreen 83, 19 21, 5 21, 5 20, 7 21, 2 -0.123 0.284 0.666 0.177 0.885 0.498 1.54 -0.851 0.904 0.347 0.46 0.427 0.057 2.35 0.355 0.691 0.607 0.217 1.43 0.391 5.62 -0.533 0.883 0.546 0.262 0.587 0.0901 3.17 PRS_PLINK_0.000199526231496888 TRUE 759.1 Anomalies of endocrine glands, congenital Both 1 12 15 congenital anomalies mediumspringgreen 12, 1 3, 0 3, 0 3, 0 3, 1 0.295 0.898 0.743 0.129 1.34 0.186 7.23 -0.54 11200000 1 0 0.583 5.9e-07 496000 PRS_PLINK_0.000199526231496888 TRUE 760 Back pain Both 247 206 17 symptoms purple 206, 247 51, 73 51, 49 51, 51 52, 74 -0.0333 0.101 0.742 0.13 0.967 0.794 1.18 -0.363 0.29 0.211 0.676 0.695 0.397 1.21 -0.474 0.285 0.0968 1.014 0.623 0.358 1.07 -0.115 0.277 0.678 0.169 0.891 0.521 1.52 PRS_PLINK_0.000199526231496888 FALSE 761 Cervicalgia Both 134 319 17 symptoms purple 319, 134 79, 40 80, 34 79, 25 80, 35 -0.103 0.108 0.342 0.466 0.902 0.731 1.11 -0.115 0.294 0.697 0.157 0.892 0.504 1.57 -0.511 0.326 0.118 0.929 0.6 0.316 1.12 -0.234 0.301 0.436 0.36 0.791 0.442 1.41 PRS_PLINK_0.000199526231496888 FALSE 763 Thoracic or lumbosacral neuritis or radiculitis, unspecified Both 44 234 17 symptoms purple 234, 44 58, 12 58, 12 58, 9 59, 11 -0.00442 0.176 0.98 0.009 0.996 0.705 1.41 -0.218 0.493 0.657 0.182 0.804 0.301 2.09 -0.303 0.561 0.59 0.229 0.739 0.236 2.23 0.033 0.493 0.947 0.024 1.03 0.391 2.72 PRS_PLINK_0.000199526231496888 TRUE 764 Sciatica Both 61 258 17 symptoms purple 258, 61 64, 11 64, 18 64, 14 65, 18 0.12 0.152 0.429 0.367 1.13 0.839 1.53 0.637 0.433 0.141 0.851 1.89 0.826 4.52 0.236 0.444 0.595 0.226 1.27 0.534 3.07 0.639 0.438 0.145 0.84 1.9 0.817 4.58 PRS_PLINK_0.000199526231496888 FALSE 765 Cervical radiculitis Both 43 120 17 symptoms purple 120, 43 30, 10 30, 16 30, 11 30, 6 -0.206 0.18 0.252 0.598 0.814 0.573 1.14 0.398 0.548 0.468 0.33 1.49 0.533 4.28 -0.214 0.601 0.722 0.141 0.807 0.253 2.52 -0.345 0.618 0.576 0.239 0.708 0.209 2.27 PRS_PLINK_0.000199526231496888 TRUE 766 Neuralgia, neuritis, and radiculitis NOS Both 86 316 17 symptoms purple 316, 86 78, 21 79, 27 79, 19 79, 19 -0.0452 0.131 0.73 0.137 0.956 0.74 1.23 0.353 0.356 0.322 0.492 1.42 0.718 2.86 -0.0803 0.387 0.836 0.078 0.923 0.434 1.96 -0.0124 0.393 0.975 0.011 0.988 0.456 2.13 PRS_PLINK_0.000199526231496888 FALSE 767 Cervicocranial/Cervicobrachial syndrome Both 2 6 17 symptoms purple 6, 2 2, 0 1, 0 1, 1 2, 1 0.364 177 0.998 0.001 1.44 0.885 2.31 -1.85 4040 1 0 0.158 8.92e-05 51.2 10.7 6400 0.999 0.001 43600 3.46e-28 7.58e+26 PRS_PLINK_0.000199526231496888 TRUE 769 Nonallopathic lesions NEC Both 30 113 17 symptoms purple 113, 30 29, 12 28, 8 28, 5 28, 5 -0.37 0.238 0.12 0.92 0.691 0.425 1.08 -0.218 0.546 0.69 0.161 0.804 0.281 2.23 -1.07 0.656 0.102 0.992 0.342 0.0874 1.14 -1.03 0.669 0.123 0.909 0.357 0.0832 1.2 PRS_PLINK_0.000199526231496888 TRUE 770 Myalgia and myositis unspecified Both 98 334 17 symptoms purple 334, 98 83, 26 83, 24 83, 27 84, 21 0.000775 0.121 0.995 0.002 1 0.791 1.27 -0.00475 0.353 0.989 0.005 0.995 0.499 1.98 0.0312 0.343 0.927 0.033 1.03 0.531 2.01 -0.0916 0.358 0.798 0.098 0.912 0.453 1.82 PRS_PLINK_0.000199526231496888 FALSE 771 Musculoskeletal symptoms referable to limbs Both 68 305 17 symptoms purple 305, 68 76, 14 76, 24 76, 14 76, 16 0.0655 0.148 0.659 0.181 1.07 0.798 1.43 0.609 0.407 0.134 0.871 1.84 0.846 4.14 0.0226 0.452 0.96 0.018 1.02 0.422 2.49 0.135 0.433 0.755 0.122 1.14 0.491 2.68 PRS_PLINK_0.000199526231496888 FALSE 771.1 Swelling of limb Both 92 296 17 symptoms purple 296, 92 73, 30 74, 31 74, 15 74, 16 -0.238 0.127 0.0617 1.21 0.788 0.614 1.01 0.015 0.331 0.964 0.016 1.02 0.535 1.93 -0.737 0.391 0.059 1.229 0.478 0.219 1 -0.572 0.383 0.135 0.869 0.564 0.265 1.17 PRS_PLINK_0.000199526231496888 FALSE 771.2 Cramp of limb Both 19 64 17 symptoms purple 64, 19 16, 9 16, 5 16, 2 16, 3 -0.556 0.429 0.195 0.711 0.574 0.244 1.3 -0.677 0.806 0.401 0.397 0.508 0.0942 2.28 -2.66 1.33 0.0445 1.352 0.0696 0.00128 0.689 -0.635 0.952 0.504 0.297 0.53 0.0769 3.02 PRS_PLINK_0.000199526231496888 TRUE 772 Symptoms of the muscles Both 44 210 17 symptoms purple 210, 44 52, 9 52, 15 52, 12 53, 8 0.0125 0.176 0.943 0.025 1.01 0.716 1.44 0.528 0.467 0.258 0.589 1.7 0.689 4.41 0.0706 0.488 0.885 0.053 1.07 0.416 2.81 -0.199 0.542 0.713 0.147 0.82 0.274 2.41 PRS_PLINK_0.000199526231496888 TRUE 772.1 Muscular wasting and disuse atrophy Both 3 34 17 symptoms purple 34, 3 9, 1 8, 0 8, 2 9, 0 -0.012 0.549 0.983 0.008 0.988 0.326 3.58 -0.304 2.2 0.89 0.051 0.738 0.00139 851 2.95 2.31 0.201 0.696 19.1 0.469 74200000 -1.25 1.71 0.465 0.333 0.287 4.58e-05 5.22 PRS_PLINK_0.000199526231496888 TRUE 772.2 Spasm of muscle Both 40 246 17 symptoms purple 246, 40 62, 10 61, 13 61, 11 62, 6 -0.0531 0.181 0.77 0.114 0.948 0.662 1.36 0.337 0.492 0.494 0.306 1.4 0.538 3.74 -0.114 0.493 0.817 0.088 0.892 0.337 2.35 -0.0905 0.593 0.879 0.056 0.913 0.271 3.1 PRS_PLINK_0.000199526231496888 TRUE 772.3 Muscle weakness Both 38 190 17 symptoms purple 190, 38 48, 10 47, 11 47, 8 48, 9 0.0112 0.192 0.953 0.021 1.01 0.693 1.48 -0.0773 0.494 0.876 0.058 0.926 0.35 2.44 -0.177 0.548 0.747 0.127 0.838 0.275 2.47 0.0213 0.54 0.969 0.014 1.02 0.35 2.95 PRS_PLINK_0.000199526231496888 TRUE 772.4 Rhabdomyolysis Both 2 10 17 symptoms purple 10, 2 3, 2 2, 0 2, 0 3, 0 -0.828 1.55 0.592 0.227 0.437 0.0228 5.17 -0.00749 364 1 0 0.993 0.73 1.33 -2.3 7180000 1 0 0.1 0.0275 0.271 -0.367 181 0.998 0.001 0.693 0.00773 53.9 PRS_PLINK_0.000199526231496888 TRUE 772.6 Facial weakness Both 2 33 17 symptoms purple 33, 2 9, 0 8, 1 8, 0 8, 1 0.756 0.768 0.325 0.488 2.13 0.301 2.73 0.622 1.73 0.719 0.144 1.86 0.0364 131 0.659 1.42 0.641 0.193 1.93 0.0837 313 PRS_PLINK_0.000199526231496888 TRUE 780 Hypothermia/Chills Both 6 46 17 symptoms purple 46, 6 12, 0 11, 3 11, 2 12, 1 -0.131 0.548 0.811 0.091 0.877 0.199 2.67 -0.368 1.72 0.83 0.081 0.692 0.00622 56.7 -0.0058 1.45 0.997 0.001 0.994 0.0287 200 0.645 1.7 0.704 0.153 1.91 0.0767 2090 PRS_PLINK_0.000199526231496888 TRUE 781 Symptoms involving nervous and musculoskeletal systems Both 40 189 17 symptoms purple 189, 40 48, 12 47, 9 47, 12 47, 7 0.00947 0.2 0.962 0.017 1.01 0.684 1.49 -0.0536 0.551 0.923 0.035 0.948 0.327 2.75 0.134 0.534 0.802 0.096 1.14 0.41 3.27 -0.285 0.565 0.613 0.212 0.752 0.247 2.2 PRS_PLINK_0.000199526231496888 TRUE 781.1 Loss of height Both 1 1 17 symptoms purple 1, 1 -0.00974 214 1 0 0.99 0.876 1.15 PRS_PLINK_0.000199526231496888 TRUE 781.2 Abnormal posture Both 1 4 17 symptoms purple 4, 1 1, 0 1, 0 1, 0 1, 1 -0.17 1440 1 0 0.844 0.345 1.07 -0.525 3910 1 0 0.591 0.573 1.75 PRS_PLINK_0.000199526231496888 TRUE 782.3 Edema Both 96 305 17 symptoms purple 305, 96 76, 30 76, 26 76, 23 76, 17 -0.161 0.127 0.205 0.689 0.851 0.664 1.09 -0.172 0.33 0.603 0.22 0.842 0.443 1.59 -0.272 0.345 0.431 0.366 0.762 0.389 1.48 -0.408 0.368 0.267 0.574 0.665 0.322 1.34 PRS_PLINK_0.000199526231496888 FALSE 782.6 Pallor and flushing Both 22 114 17 symptoms purple 114, 22 29, 3 28, 5 28, 9 29, 5 0.0326 0.285 0.909 0.041 1.03 0.59 1.85 0.622 0.863 0.471 0.327 1.86 0.369 13.2 0.61 0.749 0.415 0.382 1.84 0.446 9.29 0.116 0.873 0.894 0.049 1.12 0.208 7.86 PRS_PLINK_0.000199526231496888 TRUE 783 Fever of unknown origin Both 80 367 17 symptoms purple 367, 80 91, 20 92, 22 91, 23 92, 15 -0.0146 0.126 0.908 0.042 0.986 0.77 1.26 0.201 0.35 0.565 0.248 1.22 0.617 2.44 0.264 0.351 0.451 0.345 1.3 0.661 2.6 -0.184 0.379 0.628 0.202 0.832 0.391 1.74 PRS_PLINK_0.000199526231496888 FALSE 783.1 Postprocedural fever Both 3 24 17 symptoms purple 24, 3 6, 1 6, 2 6, 0 6, 0 -0.238 0.8 0.766 0.116 0.788 0.104 7.19 0.82 1.62 0.613 0.213 2.27 0.196 55.5 -0.0632 1.54 0.967 0.014 0.939 0.0406 62.7 0.314 3.01 0.917 0.038 1.37 2.12e-05 8380 PRS_PLINK_0.000199526231496888 TRUE 785 Abdominal pain Both 303 150 17 symptoms purple 150, 303 37, 58 37, 62 37, 100 38, 83 0.159 0.106 0.133 0.875 1.17 0.955 1.44 0.000966 0.328 0.998 0.001 1 0.53 1.88 0.425 0.302 0.159 0.799 1.53 0.856 2.74 0.151 0.318 0.636 0.196 1.16 0.627 2.15 PRS_PLINK_0.000199526231496888 FALSE 788 Syncope and collapse Both 47 346 17 symptoms purple 346, 47 86, 11 86, 19 86, 6 87, 11 0.0574 0.157 0.714 0.146 1.06 0.776 1.45 0.621 0.416 0.135 0.868 1.86 0.833 4.34 -0.479 0.499 0.338 0.472 0.62 0.215 1.67 0.116 0.446 0.794 0.1 1.12 0.459 2.76 PRS_PLINK_0.000199526231496888 TRUE 789 Nausea and vomiting Both 179 274 17 symptoms purple 274, 179 69, 41 68, 48 68, 42 69, 47 0.0385 0.101 0.704 0.152 1.04 0.854 1.27 0.104 0.294 0.723 0.141 1.11 0.629 1.95 -0.0223 0.293 0.939 0.027 0.978 0.556 1.72 0.049 0.297 0.869 0.061 1.05 0.592 1.86 PRS_PLINK_0.000199526231496888 FALSE 789.1 Persistent vomiting Both 12 87 17 symptoms purple 87, 12 22, 2 22, 2 21, 2 22, 6 0.403 0.374 0.281 0.552 1.5 0.719 3.48 -0.203 0.977 0.835 0.078 0.816 0.0778 7.07 0.817 1.04 0.434 0.363 2.26 0.268 58.9 1.53 1.03 0.135 0.87 4.64 0.673 69.4 PRS_PLINK_0.000199526231496888 TRUE 790 Nonspecific findings on examination of blood Both 32 133 17 symptoms purple 133, 32 33, 13 33, 5 33, 9 33, 5 -0.177 0.193 0.36 0.443 0.838 0.567 1.22 -0.685 0.602 0.256 0.592 0.504 0.145 1.55 -0.404 0.537 0.452 0.345 0.668 0.232 1.85 -0.579 0.614 0.346 0.461 0.561 0.157 1.78 PRS_PLINK_0.000199526231496888 TRUE 790.1 Elevated sedimentation rate Both 4 17 17 symptoms purple 17, 4 5, 2 4, 1 4, 0 4, 1 -0.928 1.07 0.388 0.412 0.395 0.0162 3.11 -2.44 23.8 0.919 0.037 0.0873 0.0723 0.106 -2.77 3.45 0.421 0.376 0.0625 4.07e-05 9.82 0.0898 1.95 0.963 0.016 1.09 0.019 20.1 PRS_PLINK_0.000199526231496888 TRUE 790.6 Other abnormal blood chemistry Both 125 318 17 symptoms purple 318, 125 79, 31 79, 30 79, 29 80, 35 0.0348 0.117 0.765 0.116 1.04 0.825 1.3 -0.0236 0.328 0.943 0.026 0.977 0.515 1.85 -0.175 0.327 0.592 0.228 0.839 0.444 1.57 0.334 0.323 0.301 0.521 1.4 0.75 2.63 PRS_PLINK_0.000199526231496888 FALSE 790.8 Elevated C-reactive protein (CRP) Both 5 33 17 symptoms purple 33, 5 8, 1 8, 1 8, 1 8, 2 0.316 0.5 0.527 0.278 1.37 0.528 4.87 1.33 2.38 0.577 0.239 3.77 0.00176 52300 -0.494 1.63 0.762 0.118 0.61 0.00229 18.5 2.04 2.04 0.317 0.499 7.72 0.299 5.35e+08 PRS_PLINK_0.000199526231496888 TRUE 790.9 Abnormal arterial blood gases Both 0 11 17 symptoms purple 11, 0 3 3 2 3 PRS_PLINK_0.000199526231496888 TRUE 791 Gangrene Both 2 15 17 symptoms purple 15, 2 4, 0 4, 0 3, 1 4, 1 0.265 0.602 0.659 0.181 1.3 0.379 4.88 -0.0289 1540 1 0 0.971 0.56 1.28 -0.29 1390 1 0 0.748 0.206 1.7 PRS_PLINK_0.000199526231496888 TRUE 792 Abnormal Papanicolaou smear of cervix and cervical HPV Female 132 149 11 genitourinary black 149, 132 38, 34 37, 31 37, 47 37, 20 -0.125 0.128 0.325 0.488 0.882 0.688 1.13 -0.301 0.369 0.415 0.382 0.74 0.363 1.49 0.354 0.342 0.3 0.523 1.42 0.743 2.75 -0.519 0.418 0.214 0.669 0.595 0.264 1.31 PRS_PLINK_0.000199526231496888 FALSE 792.1 Papanicolaou smear of cervix or vagina with atypical squamous cells Female 61 130 11 genitourinary black 130, 61 33, 15 32, 12 32, 27 33, 7 -0.0714 0.163 0.662 0.179 0.931 0.679 1.27 -0.365 0.497 0.462 0.335 0.694 0.265 1.76 0.593 0.437 0.174 0.759 1.81 0.797 4.21 -0.324 0.57 0.569 0.245 0.723 0.235 2.14 PRS_PLINK_0.000199526231496888 FALSE 794 Abnormal results of other function studies (bladder, pancreas, placenta, spleen, etc) Both 4 45 17 symptoms purple 45, 4 11, 0 11, 0 11, 4 11, 0 0.141 0.48 0.77 0.114 1.15 0.391 3.44 1.56 1.4 0.265 0.577 4.74 0.4 659 PRS_PLINK_0.000199526231496888 TRUE 795 Other and nonspecific abnormal cytological, histological and immunological findings Both 79 281 17 symptoms purple 281, 79 70, 20 70, 18 70, 23 70, 18 0.0113 0.13 0.931 0.031 1.01 0.785 1.31 -0.259 0.377 0.491 0.309 0.772 0.367 1.6 0.0642 0.352 0.855 0.068 1.07 0.54 2.11 0.00267 0.379 0.994 0.002 1 0.478 2.1 PRS_PLINK_0.000199526231496888 FALSE 795.8 Abnormal tumor markers Both 5 77 17 symptoms purple 77, 5 20, 3 19, 0 19, 1 19, 1 -0.451 0.405 0.265 0.576 0.637 0.248 1.48 -2.4 1.55 0.12 0.921 0.0903 0.000293 1.88 -0.364 1.08 0.736 0.133 0.695 0.0551 7.4 -0.919 0.987 0.352 0.454 0.399 0.0398 2.52 PRS_PLINK_0.000199526231496888 TRUE 795.81 Elevated carcinoembryonic antigen [CEA] Both 0 4 17 symptoms purple 4, 0 1 1 1 1 PRS_PLINK_0.000199526231496888 TRUE 795.82 Elevated cancer antigen 125 [CA 125] Both 1 20 17 symptoms purple 20, 1 5, 0 5, 0 5, 0 5, 1 0.166 0.748 0.825 0.084 1.18 0.183 41.4 0.512 2.52 0.839 0.076 1.67 0.0361 460 PRS_PLINK_0.000199526231496888 TRUE 796 Elevated prostate specific antigen [PSA] Male 8 40 11 genitourinary black 40, 8 10, 2 10, 3 10, 2 10, 1 -0.277 0.456 0.544 0.265 0.758 0.303 1.78 -1.28 1.67 0.445 0.352 0.279 0.0277 75.5 -0.233 1.27 0.854 0.068 0.792 0.037 16.3 -1.36 1.69 0.421 0.376 0.257 8.45e-10 4.71 PRS_PLINK_0.000199526231496888 TRUE 797 Shock Both 5 39 17 symptoms purple 39, 5 10, 3 10, 1 9, 0 10, 1 -0.0197 0.515 0.97 0.013 0.981 0.359 3.23 -1.01 1.59 0.526 0.279 0.365 0.000809 247 0.0711 1.75 0.968 0.014 1.07 0.00787 36.9 -0.247 1.33 0.853 0.069 0.781 0.0618 9.78 PRS_PLINK_0.000199526231496888 TRUE 797.1 Cardiogenic shock Both 3 13 17 symptoms purple 13, 3 4, 2 3, 1 3, 0 3, 0 0.0474 0.781 0.952 0.022 1.05 0.147 9.5 0.901 2.58 0.727 0.138 2.46 0.0544 27.3 0.584 7.37 0.937 0.028 1.79 3.43e-05 170000 -0.572 4.45 0.898 0.047 0.564 0.0659 0.493 PRS_PLINK_0.000199526231496888 TRUE 798 Malaise and fatigue Both 199 254 17 symptoms purple 254, 199 63, 46 63, 43 63, 54 64, 56 0.0185 0.103 0.857 0.067 1.02 0.835 1.24 -0.0821 0.318 0.796 0.099 0.921 0.498 1.7 -0.0536 0.294 0.856 0.068 0.948 0.536 1.67 0.0274 0.296 0.926 0.033 1.03 0.58 1.82 PRS_PLINK_0.000199526231496888 FALSE 798.1 Chronic fatigue syndrome Both 37 140 17 symptoms purple 140, 37 35, 6 35, 9 35, 12 35, 10 0.0787 0.22 0.72 0.143 1.08 0.709 1.66 0.497 0.634 0.433 0.364 1.64 0.477 6.23 0.556 0.621 0.371 0.431 1.74 0.538 6.2 0.122 0.683 0.859 0.066 1.13 0.302 4.29 PRS_PLINK_0.000199526231496888 TRUE 800 Fracture of lower limb Both 31 192 18 injuries & poisonings gray50 192, 31 47, 8 48, 9 48, 5 48, 9 0.0907 0.197 0.646 0.19 1.09 0.742 1.63 0.245 0.549 0.656 0.183 1.28 0.437 3.95 -0.509 0.624 0.414 0.383 0.601 0.158 2.09 0.354 0.609 0.561 0.251 1.43 0.436 4.94 PRS_PLINK_0.000199526231496888 TRUE 800.1 Fracture of neck of femur Both 7 35 18 injuries & poisonings gray50 35, 7 9, 3 9, 0 8, 1 9, 3 0.0538 0.548 0.922 0.035 1.06 0.318 3.09 -0.261 1.58 0.869 0.061 0.77 0.0175 71.1 -0.011 1.67 0.995 0.002 0.989 0.00719 227 0.071 1.25 0.955 0.02 1.07 0.0637 145 PRS_PLINK_0.000199526231496888 TRUE 800.2 Fracture of unspecified part of femur Both 7 46 18 injuries & poisonings gray50 46, 7 12, 1 11, 2 11, 1 12, 3 0.216 0.448 0.629 0.201 1.24 0.529 3.39 2.39 2.06 0.245 0.61 10.9 0.245 269 -0.32 1.48 0.829 0.081 0.726 0.00397 195 0.652 1.09 0.55 0.26 1.92 0.266 20.1 PRS_PLINK_0.000199526231496888 TRUE 800.3 Fracture of tibia and fibula Both 11 69 18 injuries & poisonings gray50 69, 11 18, 2 17, 5 17, 0 17, 4 -0.115 0.351 0.744 0.128 0.892 0.414 1.78 0.853 0.976 0.382 0.418 2.35 0.38 23.8 -1.43 1.36 0.291 0.537 0.239 4.08e-06 3.31 -0.303 1.25 0.809 0.092 0.739 0.0364 10.8 PRS_PLINK_0.000199526231496888 TRUE 800.4 Fracture of patella Both 5 38 18 injuries & poisonings gray50 38, 5 10, 0 9, 2 9, 1 10, 2 1.3 0.68 0.0567 1.246 3.66 1.13 18.2 2.45 1.91 0.198 0.703 11.6 0.543 136000 0.987 1.95 0.612 0.213 2.68 0.000823 942 1.19 1.77 0.501 0.3 3.29 0.0674 1300000 PRS_PLINK_0.000199526231496888 TRUE 801 Fracture of ankle and foot Both 46 215 18 injuries & poisonings gray50 215, 46 53, 15 54, 10 53, 10 54, 11 -0.0934 0.174 0.59 0.229 0.911 0.644 1.28 -0.479 0.466 0.305 0.516 0.62 0.244 1.51 -0.47 0.473 0.32 0.494 0.625 0.242 1.55 -0.221 0.495 0.655 0.184 0.802 0.299 2.11 PRS_PLINK_0.000199526231496888 TRUE 801.1 Fracture of foot Both 21 104 18 injuries & poisonings gray50 104, 21 26, 7 26, 4 26, 5 26, 5 -0.0728 0.273 0.789 0.103 0.93 0.537 1.61 -0.651 0.7 0.353 0.452 0.522 0.12 1.97 -0.235 0.655 0.719 0.143 0.79 0.219 2.71 -0.2 0.8 0.802 0.096 0.818 0.169 4.01 PRS_PLINK_0.000199526231496888 TRUE 802 Fracture of pelvis Both 6 24 18 injuries & poisonings gray50 24, 6 6, 3 6, 1 6, 0 6, 2 0.115 0.543 0.833 0.08 1.12 0.383 3.52 0.325 2.19 0.882 0.054 1.38 0.0152 112 -1.58 1.8 0.38 0.42 0.206 1.27e-05 6.97 0.484 1.93 0.802 0.096 1.62 0.0625 134 PRS_PLINK_0.000199526231496888 TRUE 803 Fracture of upper limb Both 19 162 18 injuries & poisonings gray50 162, 19 40, 4 40, 7 40, 4 41, 4 -0.0188 0.256 0.941 0.026 0.981 0.587 1.66 0.748 0.671 0.265 0.577 2.11 0.572 9.01 -0.22 0.727 0.762 0.118 0.802 0.156 3.63 -0.0862 0.734 0.907 0.043 0.917 0.195 4.21 PRS_PLINK_0.000199526231496888 TRUE 803.1 Fracture of humerus Both 5 49 18 injuries & poisonings gray50 49, 5 12, 1 12, 2 12, 0 12, 2 -0.217 0.522 0.677 0.169 0.805 0.145 3.57 0.00863 1.23 0.994 0.002 1.01 0.000232 12.1 0.169 1.55 0.914 0.039 1.18 0.0087 130 -0.0452 1.49 0.976 0.011 0.956 0.000219 69.4 PRS_PLINK_0.000199526231496888 TRUE 803.2 Fracture of radius and ulna Both 11 102 18 injuries & poisonings gray50 102, 11 26, 2 25, 3 25, 4 26, 2 0.0746 0.386 0.847 0.072 1.08 0.453 2.46 0.614 1.05 0.56 0.252 1.85 0.109 20 0.157 0.976 0.872 0.06 1.17 0.0364 10.4 0.169 0.958 0.86 0.066 1.18 0.136 15.5 PRS_PLINK_0.000199526231496888 TRUE 803.21 Colles' fracture Both 4 14 18 injuries & poisonings gray50 14, 4 4, 2 3, 0 3, 0 4, 2 -0.0414 1.08 0.969 0.013 0.959 0.0695 12.1 -1.82 10.5 0.862 0.064 0.163 0.147 0.179 -3.13 23.9 0.896 0.048 0.0439 0.0403 0.0467 0.282 1.8 0.876 0.058 1.33 0.0771 37.6 PRS_PLINK_0.000199526231496888 TRUE 803.3 Fracture of clavicle or scapula Both 5 28 18 injuries & poisonings gray50 28, 5 7, 1 7, 2 7, 1 7, 1 0.375 0.657 0.568 0.246 1.46 0.48 6.86 1.12 1.6 0.483 0.316 3.07 0.224 150 0.036 1.82 0.984 0.007 1.04 0.0147 25 0.808 1.82 0.658 0.182 2.24 0.0046 18200 PRS_PLINK_0.000199526231496888 TRUE 804 Fracture of hand or wrist Both 18 135 18 injuries & poisonings gray50 135, 18 34, 1 34, 8 33, 1 34, 8 0.279 0.259 0.282 0.55 1.32 0.789 2.27 2.11 0.881 0.0166 1.779 8.25 1.49 10.2 -0.0574 1.01 0.955 0.02 0.944 0.0642 14.1 1.78 0.906 0.0498 1.303 5.91 1.12 61 PRS_PLINK_0.000199526231496888 TRUE 805 Fracture of vertebral column without mention of spinal cord injury Both 14 78 18 injuries & poisonings gray50 78, 14 20, 4 19, 3 19, 3 20, 4 0.152 0.297 0.608 0.216 1.16 0.65 2.16 -0.468 0.975 0.631 0.2 0.626 0.074 3.9 -0.685 0.917 0.455 0.342 0.504 0.0728 2.76 0.403 0.858 0.638 0.195 1.5 0.288 8.99 PRS_PLINK_0.000199526231496888 TRUE 807 Fracture of ribs Both 11 34 18 injuries & poisonings gray50 34, 11 9, 2 8, 1 8, 3 9, 5 0.406 0.436 0.351 0.454 1.5 0.657 4.93 0.0666 1.34 0.96 0.018 1.07 0.0543 41.6 0.942 1.42 0.508 0.294 2.56 0.229 403 1.2 1.26 0.341 0.468 3.32 0.332 4410 PRS_PLINK_0.000199526231496888 TRUE 809 Fracture of unspecified bones Both 28 257 18 injuries & poisonings gray50 257, 28 65, 5 64, 11 64, 7 64, 5 -0.00783 0.199 0.969 0.014 0.992 0.666 1.48 0.917 0.557 0.0995 1.002 2.5 0.85 8.26 0.111 0.59 0.85 0.07 1.12 0.334 3.88 0.299 0.713 0.675 0.171 1.35 0.306 6.31 PRS_PLINK_0.000199526231496888 TRUE 816 Cerebral laceration and contusion Both 0 3 18 injuries & poisonings gray50 3, 0 1 1 1 1 PRS_PLINK_0.000199526231496888 TRUE 817 Concussion Both 17 107 18 injuries & poisonings gray50 107, 17 27, 4 27, 7 26, 2 27, 4 0.0243 0.297 0.935 0.029 1.02 0.561 1.91 0.797 0.819 0.331 0.481 2.22 0.464 13.3 -0.448 0.832 0.59 0.229 0.639 0.0868 3.44 -0.42 0.847 0.62 0.208 0.657 0.108 3.58 PRS_PLINK_0.000199526231496888 TRUE 818 Intracranial hemorrhage (injury) Both 4 14 18 injuries & poisonings gray50 14, 4 4, 3 3, 1 3, 0 4, 0 -0.766 0.833 0.358 0.447 0.465 0.0457 5.01 -1.78 3.37 0.597 0.224 0.168 0.000258 23.2 -1.29 11.4 0.91 0.041 0.276 0.255 0.299 -4.78e-14 5.43 1 0 1 0.000114 3500 PRS_PLINK_0.000199526231496888 TRUE 818.1 Subdural hemorrhage (injury) Both 1 4 18 injuries & poisonings gray50 4, 1 1, 1 1, 0 1, 0 1, 0 -0.00521 315 1 0 0.995 0.92 1.07 0.0189 59.1 1 0 1.02 0.951 1.16 0.0211 51.9 1 0 1.02 0.903 1.14 -0.273 1610 1 0 0.761 0.225 1.53 PRS_PLINK_0.000199526231496888 TRUE 818.2 Subarachnoid hemorrhage (injury) Both 1 6 18 injuries & poisonings gray50 6, 1 2, 1 1, 0 1, 0 2, 0 0.0494 1140 1 0 1.05 0.77 1.51 0.368 21000 1 0 1.44 0.236 12.4 0.119 4940 1 0 1.13 0.637 1.29 1.8 2020 0.999 0 6.07 0.0172 1980 PRS_PLINK_0.000199526231496888 TRUE 819 Skull and face fracture and other intercranial injury Both 33 199 18 injuries & poisonings gray50 199, 33 50, 7 50, 14 49, 8 50, 4 -0.26 0.204 0.203 0.693 0.771 0.51 1.15 0.89 0.56 0.112 0.95 2.43 0.838 7.83 0.141 0.559 0.801 0.096 1.15 0.377 3.63 -0.679 0.649 0.296 0.529 0.507 0.121 1.83 PRS_PLINK_0.000199526231496888 TRUE 830 Dislocation Both 56 344 18 injuries & poisonings gray50 344, 56 85, 15 86, 12 86, 11 86, 18 0.0778 0.152 0.61 0.215 1.08 0.8 1.47 -0.164 0.441 0.711 0.148 0.849 0.348 2.03 -0.479 0.444 0.281 0.552 0.62 0.25 1.48 0.0975 0.4 0.807 0.093 1.1 0.501 2.43 PRS_PLINK_0.000199526231496888 FALSE 835 Internal derangement of knee Both 23 189 18 injuries & poisonings gray50 189, 23 47, 5 47, 6 47, 6 47, 6 0.087 0.246 0.724 0.14 1.09 0.655 1.81 0.0449 0.618 0.942 0.026 1.05 0.295 3.82 -0.0804 0.632 0.899 0.046 0.923 0.258 3.26 0.135 0.646 0.835 0.079 1.14 0.312 4.53 PRS_PLINK_0.000199526231496888 TRUE 836 Traumatic arthropathy Both 3 29 18 injuries & poisonings gray50 29, 3 8, 1 7, 1 7, 0 7, 1 -0.176 0.948 0.853 0.069 0.839 0.0265 11.9 -0.485 1.6 0.762 0.118 0.616 0.0205 8.62 -1.04 2 0.603 0.22 0.354 0.00186 18.7 -0.46 2.13 0.829 0.081 0.632 1.55e-06 10100 PRS_PLINK_0.000199526231496888 TRUE 840 Sprains and strains Both 129 302 18 injuries & poisonings gray50 302, 129 75, 32 75, 41 75, 22 76, 34 -0.0265 0.11 0.81 0.092 0.974 0.786 1.21 0.351 0.302 0.245 0.61 1.42 0.794 2.57 -0.582 0.347 0.0936 1.029 0.559 0.282 1.08 0.0903 0.314 0.773 0.112 1.09 0.598 2.01 PRS_PLINK_0.000199526231496888 FALSE 840.1 Muscle/tendon sprain Both 3 18 18 injuries & poisonings gray50 18, 3 5, 1 4, 1 4, 0 5, 1 0.13 0.63 0.837 0.077 1.14 0.387 5.54 0.781 2.57 0.761 0.118 2.18 0.0117 488 0.757 3.98 0.849 0.071 2.13 0.00272 1120 0.503 2.43 0.836 0.078 1.65 1.49 1.92 PRS_PLINK_0.000199526231496888 TRUE 840.2 Rotator cuff (capsule) sprain Both 16 74 18 injuries & poisonings gray50 74, 16 19, 3 18, 3 18, 3 19, 7 0.305 0.332 0.358 0.446 1.36 0.722 2.64 0.427 0.875 0.626 0.203 1.53 0.278 9.31 0.277 0.882 0.753 0.123 1.32 0.232 8.77 2.11 1.09 0.0527 1.279 8.24 1.25 120 PRS_PLINK_0.000199526231496888 TRUE 840.3 Joint/ligament sprain Both 52 228 18 injuries & poisonings gray50 228, 52 56, 6 57, 24 57, 6 57, 16 0.101 0.165 0.539 0.268 1.11 0.801 1.53 1.31 0.489 0.00736 2.133 3.71 1.48 10.5 -0.0844 0.585 0.885 0.053 0.919 0.278 3.02 0.745 0.502 0.138 0.86 2.11 0.812 6.03 PRS_PLINK_0.000199526231496888 FALSE 841 Sprains and strains of back and neck Both 36 156 18 injuries & poisonings gray50 156, 36 38, 7 39, 12 39, 8 39, 9 0.0205 0.187 0.913 0.04 1.02 0.707 1.48 0.736 0.568 0.195 0.709 2.09 0.706 6.61 0.0763 0.559 0.891 0.05 1.08 0.363 3.29 0.246 0.581 0.672 0.173 1.28 0.415 4.1 PRS_PLINK_0.000199526231496888 TRUE 842 Other sprains and strains Both 31 109 18 injuries & poisonings gray50 109, 31 27, 6 27, 9 27, 9 27, 7 0.0201 0.203 0.921 0.036 1.02 0.691 1.53 0.7 0.662 0.29 0.537 2.01 0.58 7.8 -0.0355 0.623 0.955 0.02 0.965 0.283 3.21 0.451 0.647 0.486 0.313 1.57 0.46 5.57 PRS_PLINK_0.000199526231496888 TRUE 850 Hemorrhage or hematoma complicating a procedure Both 24 152 18 injuries & poisonings gray50 152, 24 37, 11 38, 2 38, 5 38, 6 0.0541 0.225 0.81 0.092 1.06 0.68 1.67 -1.92 0.841 0.0227 1.644 0.147 0.0157 0.671 -0.478 0.598 0.424 0.373 0.62 0.184 1.93 -0.233 0.567 0.681 0.167 0.792 0.256 2.36 PRS_PLINK_0.000199526231496888 TRUE 851 Complications of transplants and reattached limbs Both 48 186 18 injuries & poisonings gray50 186, 48 47, 11 46, 14 46, 13 47, 10 -0.0457 0.177 0.796 0.099 0.955 0.677 1.35 0.415 0.536 0.439 0.357 1.51 0.534 4.49 0.318 0.495 0.52 0.284 1.37 0.529 3.66 0.162 0.53 0.76 0.119 1.18 0.419 3.34 PRS_PLINK_0.000199526231496888 TRUE 853 Complication of colostomy or enterostomy Both 2 38 18 injuries & poisonings gray50 38, 2 10, 0 9, 2 9, 0 10, 0 -0.684 0.737 0.353 0.452 0.505 0.00772 3.08 0.0674 1.79 0.97 0.013 1.07 0.00295 378 PRS_PLINK_0.000199526231496888 TRUE 854 Complications of cardiac/vascular device, implant, and graft Both 22 125 18 injuries & poisonings gray50 125, 22 31, 8 31, 7 31, 3 31, 4 -0.247 0.249 0.321 0.493 0.781 0.475 1.29 0.0739 0.694 0.915 0.038 1.08 0.276 4.41 -0.424 0.723 0.558 0.254 0.655 0.141 2.68 -0.443 0.743 0.551 0.259 0.642 0.134 2.74 PRS_PLINK_0.000199526231496888 TRUE 855 Complication of nervous system device, implant, and graft Both 2 23 18 injuries & poisonings gray50 23, 2 6, 0 6, 0 5, 2 6, 0 -0.187 0.791 0.814 0.09 0.83 0.0855 4.62 1.4 3.16 0.657 0.183 4.08 0.0365 224000 PRS_PLINK_0.000199526231496888 TRUE 856 Vascular complications of surgery and medical procedures Both 3 29 18 injuries & poisonings gray50 29, 3 8, 0 7, 2 7, 0 7, 1 0.366 0.601 0.543 0.266 1.44 0.497 8.53 1.78 1.93 0.357 0.447 5.92 0.238 10700 1.21 1.98 0.54 0.268 3.37 0.138 1970 PRS_PLINK_0.000199526231496888 TRUE 857 Mechanical complication of unspecified genitourinary device, implant, and graft Both 37 157 18 injuries & poisonings gray50 157, 37 39, 6 39, 8 39, 10 39, 13 0.415 0.216 0.0543 1.265 1.51 1.01 2.33 0.178 0.757 0.814 0.089 1.2 0.268 6.08 0.288 0.591 0.626 0.203 1.33 0.43 4.31 0.847 0.627 0.177 0.753 2.33 0.724 8.64 PRS_PLINK_0.000199526231496888 TRUE 858 Complication of internal orthopedic device Both 13 190 18 injuries & poisonings gray50 190, 13 48, 9 47, 2 47, 0 48, 2 -0.543 0.284 0.0557 1.254 0.581 0.316 1.04 -1.29 0.725 0.074 1.131 0.274 0.0477 1.07 -2.94 1.24 0.0177 1.751 0.053 0.000413 0.439 -1.21 0.73 0.0985 1.006 0.3 0.0515 1.21 PRS_PLINK_0.000199526231496888 TRUE 859 Complication due to other implant and internal device Both 16 188 18 injuries & poisonings gray50 188, 16 47, 4 47, 5 47, 4 47, 3 -0.258 0.249 0.3 0.522 0.773 0.463 1.28 0.228 0.68 0.737 0.132 1.26 0.317 5.42 -0.241 0.712 0.735 0.134 0.786 0.17 3.36 -0.686 0.837 0.412 0.385 0.503 0.0724 2.67 PRS_PLINK_0.000199526231496888 TRUE 860 Bone marrow or stem cell transplant Both 1 19 2 neoplasms darkcyan 19, 1 5, 0 5, 0 4, 0 5, 1 0.0802 0.768 0.917 0.038 1.08 0.0583 10.6 0.289 5.52 0.958 0.018 1.33 4.62e-06 11500 PRS_PLINK_0.000199526231496888 TRUE 870 Open wounds of head; neck; and trunk Both 56 298 18 injuries & poisonings gray50 298, 56 74, 18 74, 16 74, 12 75, 10 -0.228 0.151 0.129 0.888 0.796 0.59 1.07 -0.0862 0.391 0.825 0.083 0.917 0.429 1.96 -0.342 0.412 0.407 0.391 0.71 0.309 1.59 -0.387 0.429 0.367 0.435 0.679 0.283 1.56 PRS_PLINK_0.000199526231496888 FALSE 870.1 Open wound or laceration of eye or eyelid Both 3 11 18 injuries & poisonings gray50 11, 3 3, 0 3, 1 2, 1 3, 1 0.0155 1.33 0.991 0.004 1.02 0.000241 37.9 0.156 2070 1 0 1.17 0.347 11.1 0.201 1810 1 0 1.22 0.557 3.4 -1.1 384 0.998 0.001 0.333 0.0135 13.5 PRS_PLINK_0.000199526231496888 TRUE 870.2 Open wound of ear Both 3 13 18 injuries & poisonings gray50 13, 3 4, 1 3, 0 3, 1 3, 1 0.672 1.02 0.509 0.293 1.96 0.295 26.5 -0.268 89.7 0.998 0.001 0.765 0.115 0.299 -0.132 3.6 0.971 0.013 0.877 4.55e-06 404 3.28 5.06 0.517 0.286 26.5 0.0372 172000 PRS_PLINK_0.000199526231496888 TRUE 870.3 Other open wound of head and face Both 14 98 18 injuries & poisonings gray50 98, 14 24, 5 24, 4 24, 2 25, 3 -0.00416 0.262 0.987 0.006 0.996 0.588 1.7 0.32 0.784 0.684 0.165 1.38 0.298 7.38 -0.562 0.865 0.516 0.287 0.57 0.0859 3.47 -0.431 0.779 0.58 0.237 0.65 0.137 2.88 PRS_PLINK_0.000199526231496888 TRUE 870.4 Open wound of nose and sinus Both 0 10 18 injuries & poisonings gray50 10, 0 3 2 2 3 PRS_PLINK_0.000199526231496888 TRUE 870.5 Open wound of lip and mouth Both 2 19 18 injuries & poisonings gray50 19, 2 5, 0 5, 0 4, 1 5, 1 0.94 0.935 0.315 0.502 2.56 0.552 343 1.49 2.91 0.608 0.216 4.44 0.0878 5.03 0.581 8.59 0.946 0.024 1.79 1.39 2.45 PRS_PLINK_0.000199526231496888 TRUE 870.6 Open wound of neck Both 2 13 18 injuries & poisonings gray50 13, 2 4, 0 3, 1 3, 0 3, 1 0.225 1.42 0.875 0.058 1.25 0.00614 46.7 -1.42 4.76 0.765 0.116 0.241 0.000153 242 -1.19e-12 12.8 1 0 1 7.76e-05 12800 PRS_PLINK_0.000199526231496888 TRUE 870.8 Open wound of genital organs Both 5 23 18 injuries & poisonings gray50 23, 5 6, 1 6, 2 5, 1 6, 1 0.0478 0.889 0.957 0.019 1.05 0.152 8.34 -0.907 2.21 0.682 0.166 0.404 0.000162 12.9 0.174 2.36 0.941 0.026 1.19 0.00398 1570 0.545 2.49 0.827 0.083 1.72 0.0113 708 PRS_PLINK_0.000199526231496888 TRUE 871 Open wounds of extremities Both 50 253 18 injuries & poisonings gray50 253, 50 63, 17 63, 15 63, 8 63, 10 -0.165 0.152 0.279 0.555 0.848 0.627 1.14 0.0344 0.416 0.934 0.03 1.03 0.46 2.33 -0.825 0.479 0.0852 1.069 0.438 0.162 1.1 -0.436 0.445 0.327 0.485 0.647 0.263 1.53 PRS_PLINK_0.000199526231496888 TRUE 871.1 Open wound of hand except finger(s) Both 14 46 18 injuries & poisonings gray50 46, 14 11, 4 11, 6 11, 2 12, 2 0.041 0.309 0.895 0.048 1.04 0.578 1.92 0.245 0.848 0.773 0.112 1.28 0.257 6.57 -0.746 1.09 0.492 0.308 0.474 0.0516 3.44 -0.684 1.2 0.57 0.244 0.505 0.0517 4 PRS_PLINK_0.000199526231496888 TRUE 871.2 Open wound of finger(s) Both 16 75 18 injuries & poisonings gray50 75, 16 19, 2 19, 5 18, 4 19, 5 0.046 0.266 0.863 0.064 1.05 0.631 1.78 0.502 0.902 0.578 0.238 1.65 0.278 13.4 0.0872 0.945 0.926 0.033 1.09 0.149 7.95 0.696 0.885 0.431 0.365 2.01 0.4 13.3 PRS_PLINK_0.000199526231496888 TRUE 871.3 Open wound of foot except toe(s) alone Both 5 22 18 injuries & poisonings gray50 22, 5 6, 2 5, 1 5, 2 6, 0 -1.27 0.92 0.169 0.773 0.282 0.000222 1.21 1.26 2.71 0.642 0.193 3.53 0.0409 6020 -0.311 2.42 0.898 0.047 0.733 0.00141 1030 -0.659 3.13 0.833 0.079 0.517 4.79e-05 69.6 PRS_PLINK_0.000199526231496888 TRUE 871.4 Open wound of toe(s) Both 6 16 18 injuries & poisonings gray50 16, 6 4, 3 4, 2 4, 0 4, 1 0.13 0.672 0.846 0.073 1.14 0.338 29.9 0.0339 2.76 0.99 0.004 1.03 0.00495 445 -1.59 14.9 0.915 0.039 0.203 0.185 0.223 -0.025 2.56 0.992 0.003 0.975 0.0189 7360 PRS_PLINK_0.000199526231496888 TRUE 872 Traumatic amputation Both 1 36 18 injuries & poisonings gray50 36, 1 9, 0 9, 0 9, 1 9, 0 -0.0416 0.624 0.947 0.024 0.959 0.126 8.24 -0.0259 1.57 0.987 0.006 0.974 0.00892 47.9 PRS_PLINK_0.000199526231496888 TRUE 874 Complication of amputation stump Both 0 7 18 injuries & poisonings gray50 7, 0 2 2 1 2 PRS_PLINK_0.000199526231496888 TRUE 875 Non-healing surgical wound Both 2 49 18 injuries & poisonings gray50 49, 2 13, 1 12, 0 12, 1 12, 0 -0.0783 0.633 0.902 0.045 0.925 0.174 5.62 -1 1.41 0.476 0.323 0.366 0.00346 5.66 -0.285 1.25 0.819 0.087 0.752 0.0499 9.21 -0.803 1.57 0.61 0.215 0.448 0.00326 13 PRS_PLINK_0.000199526231496888 TRUE 876 Posttraumatic wound infection not elsewhere classified Both 10 48 18 injuries & poisonings gray50 48, 10 12, 5 12, 0 12, 1 12, 4 -0.134 0.388 0.73 0.137 0.875 0.406 1.84 -1.98 1.44 0.169 0.772 0.138 0.000432 1.36 -0.757 1.01 0.456 0.341 0.469 0.0511 2.72 -0.151 1.03 0.884 0.054 0.86 0.105 5.54 PRS_PLINK_0.000199526231496888 TRUE 907 Injuries to the nervous system Both 14 82 18 injuries & poisonings gray50 82, 14 21, 4 20, 4 20, 4 21, 2 -0.0466 0.297 0.875 0.058 0.954 0.523 1.69 0.281 0.852 0.741 0.13 1.32 0.261 7.55 -0.258 0.848 0.761 0.118 0.773 0.146 3.81 0.602 1.02 0.554 0.257 1.83 0.233 19.4 PRS_PLINK_0.000199526231496888 TRUE 910 Superficial injury, infected Both 3 7 18 injuries & poisonings gray50 7, 3 2, 2 2, 1 1, 0 2, 0 -2.56 3.14 0.414 0.383 0.0774 0.000239 4.21 5.37 40900 1 0 215 1.13e-09 7.16e+13 0.657 7220 1 0 1.93 0.107 288 0.0777 1880 1 0 1.08 0.736 2.56 PRS_PLINK_0.000199526231496888 TRUE 911 Blister Both 7 31 18 injuries & poisonings gray50 31, 7 8, 4 8, 1 7, 0 8, 2 -0.64 0.581 0.27 0.568 0.527 0.0379 1.51 -1.95 2.14 0.363 0.44 0.142 6.77e-06 8.33 -1.49 1.8 0.408 0.39 0.225 1.5e-05 4.93 -0.345 1.39 0.804 0.095 0.708 0.0324 16.7 PRS_PLINK_0.000199526231496888 TRUE 912 Insect bite Both 16 53 18 injuries & poisonings gray50 53, 16 14, 3 13, 3 13, 4 13, 6 0.496 0.352 0.16 0.797 1.64 0.861 3.31 0.165 1.22 0.892 0.05 1.18 0.0968 12.6 0.734 1.09 0.5 0.301 2.08 0.288 31 1.01 1.06 0.339 0.47 2.76 0.437 22.1 PRS_PLINK_0.000199526231496888 TRUE 913 Toxic effect of venom Both 8 47 18 injuries & poisonings gray50 47, 8 11, 3 12, 3 11, 2 12, 0 -0.32 0.411 0.437 0.359 0.727 0.303 1.72 0.111 1.1 0.92 0.036 1.12 0.126 11.3 -0.394 1.36 0.772 0.112 0.674 0.0233 8.25 -1.84 1.77 0.299 0.524 0.159 0.000208 6.11 PRS_PLINK_0.000199526231496888 TRUE 916 Contusion Both 82 330 18 injuries & poisonings gray50 330, 82 82, 29 82, 20 82, 20 83, 13 -0.199 0.127 0.117 0.931 0.82 0.638 1.05 -0.259 0.333 0.437 0.36 0.772 0.399 1.47 -0.426 0.335 0.204 0.69 0.653 0.335 1.25 -0.826 0.373 0.0268 1.572 0.438 0.205 0.892 PRS_PLINK_0.000199526231496888 FALSE 930 Allergic reaction to food Both 19 67 18 injuries & poisonings gray50 67, 19 17, 7 17, 5 16, 2 17, 5 -0.204 0.281 0.467 0.331 0.815 0.464 1.38 -0.345 0.791 0.663 0.178 0.708 0.139 3.21 -1.08 0.894 0.229 0.641 0.341 0.0502 1.7 -0.371 0.763 0.627 0.203 0.69 0.158 2.81 PRS_PLINK_0.000199526231496888 TRUE 931 Contact dermatitis and other eczema due to plants [except food] Both 14 45 13 dermatologic firebrick 45, 14 12, 6 11, 0 11, 5 11, 3 -0.0188 0.342 0.956 0.019 0.981 0.52 1.84 -1.19 1.35 0.377 0.424 0.304 0.00414 3.82 -0.0669 0.974 0.945 0.024 0.935 0.143 6.27 -0.579 1.01 0.565 0.248 0.56 0.0799 4.74 PRS_PLINK_0.000199526231496888 TRUE 938 Dermatitis due to solar radiation Both 88 181 13 dermatologic firebrick 181, 88 46, 21 45, 18 45, 20 45, 29 0.0941 0.145 0.517 0.287 1.1 0.831 1.46 0.108 0.443 0.807 0.093 1.11 0.476 2.62 -0.195 0.435 0.654 0.185 0.823 0.357 1.88 0.422 0.416 0.31 0.509 1.53 0.692 3.45 PRS_PLINK_0.000199526231496888 FALSE 938.1 Acute dermatitis due to solar radiation Both 9 18 13 dermatologic firebrick 18, 9 5, 2 4, 1 4, 1 5, 5 0.586 0.537 0.275 0.56 1.8 0.737 8.78 4.39 8.73 0.615 0.211 80.9 0.000388 101 -0.681 2.66 0.798 0.098 0.506 0.00516 61.5 1.4 1.76 0.426 0.371 4.07 0.234 4.66 PRS_PLINK_0.000199526231496888 TRUE 938.2 Chronic dermatitis due to solar radiation Both 83 176 13 dermatologic firebrick 176, 83 44, 21 44, 16 44, 19 44, 27 0.102 0.151 0.498 0.303 1.11 0.828 1.49 -0.043 0.458 0.925 0.034 0.958 0.396 2.3 -0.282 0.441 0.522 0.282 0.754 0.322 1.74 0.329 0.422 0.435 0.362 1.39 0.623 3.17 PRS_PLINK_0.000199526231496888 FALSE 939 Atopic/contact dermatitis due to other or unspecified Both 139 207 13 dermatologic firebrick 207, 139 52, 36 52, 29 51, 33 52, 41 -0.0223 0.12 0.853 0.069 0.978 0.776 1.23 -0.284 0.35 0.418 0.379 0.753 0.382 1.47 -0.214 0.337 0.525 0.28 0.807 0.421 1.53 -0.203 0.342 0.553 0.258 0.816 0.421 1.56 PRS_PLINK_0.000199526231496888 FALSE 939.1 Contact and allergic dermatitis of eyelid Both 3 1 13 dermatologic firebrick 1, 3 0.723 15500 1 0 2.06 3.55e-15 3.37e+15 PRS_PLINK_0.000199526231496888 TRUE 941 Adverse reaction to serum or vaccine Both 4 18 18 injuries & poisonings gray50 18, 4 5, 3 4, 0 4, 1 5, 0 -0.219 0.951 0.818 0.087 0.803 0.117 4.43 -0.157 2.32 0.946 0.024 0.854 0.0023 35.1 -0.477 1.67 0.776 0.11 0.621 0.415 2.21 1.2 4.16 0.772 0.112 3.33 2.9 3.74 PRS_PLINK_0.000199526231496888 TRUE 942 Infusion and transfusion reaction Both 4 20 18 injuries & poisonings gray50 20, 4 5, 2 5, 0 5, 0 5, 2 0.509 0.876 0.561 0.251 1.66 0.422 1.83 -1.45 2.43 0.551 0.259 0.234 2.14e-06 5.92 -2.26 2.89 0.434 0.363 0.104 4.73e-07 6.11 -1.28 2.67 0.631 0.2 0.277 1.06e-06 16.6 PRS_PLINK_0.000199526231496888 TRUE 946 Anaphylactic shock NOS Both 15 34 18 injuries & poisonings gray50 34, 15 9, 4 8, 6 8, 2 9, 3 -0.133 0.347 0.701 0.154 0.875 0.465 1.66 0.929 1.05 0.376 0.425 2.53 0.44 19.1 -1.26 1.22 0.303 0.519 0.283 0.0152 2.13 -0.566 1.06 0.592 0.227 0.568 0.0787 3.4 PRS_PLINK_0.000199526231496888 TRUE 947 Urticaria Both 30 111 13 dermatologic firebrick 111, 30 28, 10 28, 6 27, 6 28, 8 0.0163 0.218 0.94 0.027 1.02 0.666 1.56 -0.281 0.647 0.664 0.178 0.755 0.206 2.62 -0.421 0.587 0.474 0.325 0.656 0.207 1.98 -0.235 0.586 0.689 0.162 0.791 0.249 2.4 PRS_PLINK_0.000199526231496888 TRUE 949 Allergies, other Both 133 207 18 injuries & poisonings gray50 207, 133 52, 33 52, 22 51, 36 52, 41 0.0573 0.122 0.64 0.194 1.06 0.836 1.34 -0.309 0.381 0.418 0.379 0.734 0.35 1.52 -0.165 0.343 0.63 0.201 0.848 0.437 1.63 0.126 0.347 0.716 0.145 1.13 0.582 2.22 PRS_PLINK_0.000199526231496888 FALSE 952 Spinal cord injury without evidence of spinal bone injury Both 11 39 18 injuries & poisonings gray50 39, 11 10, 3 10, 3 9, 2 10, 3 0.288 0.444 0.517 0.287 1.33 0.583 3.25 0.529 1.57 0.736 0.133 1.7 2.72e-05 293 -1.1 1.74 0.528 0.277 0.333 0.00689 6.29 0.959 1.15 0.404 0.394 2.61 0.351 56.6 PRS_PLINK_0.000199526231496888 TRUE 957 Injury to other and unspecified nerves Both 1 14 18 injuries & poisonings gray50 14, 1 4, 1 3, 0 3, 0 4, 0 0.132 0.802 0.869 0.061 1.14 0.139 11.7 0.301 188 0.999 0.001 1.35 0.273 4.3 -2.47e-12 14.9 1 0 1 0.00117 842 0.0378 19.4 0.998 0.001 1.04 0.233 3.35 PRS_PLINK_0.000199526231496888 TRUE 958 Certain early complications of trauma or procedure Both 14 102 18 injuries & poisonings gray50 102, 14 26, 4 25, 1 25, 3 26, 6 0.384 0.316 0.224 0.65 1.47 0.802 2.81 -0.335 0.924 0.717 0.144 0.715 0.0802 6.8 -0.000946 0.775 0.999 0 0.999 0.213 4.81 0.528 0.744 0.478 0.321 1.7 0.417 7.43 PRS_PLINK_0.000199526231496888 TRUE 958.1 Postoperative shock Both 0 8 18 injuries & poisonings gray50 8, 0 2 2 2 2 PRS_PLINK_0.000199526231496888 TRUE 958.2 Traumatic and surgical subcutaneous emphysema Both 3 11 18 injuries & poisonings gray50 11, 3 3, 0 3, 1 2, 2 3, 0 1.11 2.8 0.691 0.161 3.04 2.62 3.45 0.0638 465 1 0 1.07 0.308 3.28 -0.000125 467 1 0 1 0.714 1.41 PRS_PLINK_0.000199526231496888 TRUE 960 Poisoning by antibiotics Both 37 185 18 injuries & poisonings gray50 185, 37 47, 3 46, 7 46, 14 46, 13 0.445 0.201 0.0264 1.578 1.56 1.06 2.34 0.843 0.668 0.207 0.684 2.32 0.631 10.4 1.38 0.619 0.0261 1.583 3.97 1.26 16.2 1.38 0.626 0.0273 1.563 3.98 1.24 16.2 PRS_PLINK_0.000199526231496888 TRUE 960.1 Adverse effects of antibacterials (not penicillins) Both 2 37 18 injuries & poisonings gray50 37, 2 10, 0 9, 0 9, 0 9, 2 0.998 0.712 0.161 0.793 2.71 0.749 1350 2.09 2.11 0.321 0.494 8.11 0.108 2330 PRS_PLINK_0.000199526231496888 TRUE 960.2 Allergy/adverse effect of penicillin Both 25 122 18 injuries & poisonings gray50 122, 25 31, 1 30, 4 30, 9 31, 11 0.726 0.271 0.00726 2.139 2.07 1.25 3.66 1.63 1.25 0.194 0.712 5.08 0.493 268 1.55 0.863 0.0731 1.136 4.7 0.964 43.2 1.96 0.863 0.0231 1.636 7.1 1.55 64.6 PRS_PLINK_0.000199526231496888 TRUE 961 Poisoning by other anti-infectives Both 16 47 18 injuries & poisonings gray50 47, 16 12, 4 12, 3 11, 1 12, 8 0.487 0.366 0.183 0.736 1.63 0.824 3.43 -0.636 1.11 0.566 0.247 0.529 0.0508 4.02 -0.985 1.27 0.437 0.359 0.374 0.0119 3.37 0.715 0.816 0.381 0.419 2.04 0.48 10.3 PRS_PLINK_0.000199526231496888 TRUE 961.1 Poisoning/allergy of sulfonamides Both 20 83 18 injuries & poisonings gray50 83, 20 21, 7 21, 0 20, 7 21, 6 -0.0334 0.258 0.897 0.047 0.967 0.589 1.59 -2.43 1.26 0.0539 1.268 0.0882 0.000529 0.722 0.065 0.681 0.924 0.034 1.07 0.297 4.02 -0.0963 0.696 0.89 0.051 0.908 0.243 3.4 PRS_PLINK_0.000199526231496888 TRUE 962 Poisoning by hormones and synthetic substitutes Both 11 71 18 injuries & poisonings gray50 71, 11 18, 3 18, 3 17, 2 18, 3 0.25 0.374 0.504 0.298 1.28 0.609 2.87 0.33 0.876 0.706 0.151 1.39 0.254 8.99 -0.042 0.964 0.965 0.015 0.959 0.117 6.41 0.266 1.12 0.813 0.09 1.3 0.105 11.7 PRS_PLINK_0.000199526231496888 TRUE 962.1 Adrenal cortical steroids causing adverse effects in therapeutic use Both 7 32 18 injuries & poisonings gray50 32, 7 7, 0 8, 5 8, 1 8, 1 0.3 0.541 0.579 0.237 1.35 0.497 4.51 1.83 1.43 0.2 0.699 6.24 0.724 743 0.45 1.58 0.775 0.111 1.57 0.0349 45.7 0.797 1.81 0.659 0.181 2.22 0.098 1490000 PRS_PLINK_0.000199526231496888 TRUE 962.2 Insulins and antidiabetic agents causing adverse effects in therapeutic use Both 0 5 18 injuries & poisonings gray50 5, 0 2 1 1 1 PRS_PLINK_0.000199526231496888 TRUE 962.3 Hormones and synthetic substitutes causing adverse effects in therapeutic use Both 5 43 18 injuries & poisonings gray50 43, 5 11, 1 11, 0 10, 2 11, 2 0.331 0.547 0.545 0.263 1.39 0.413 8.79 0.183 1.51 0.904 0.044 1.2 0.00616 98.7 1.07 1.55 0.49 0.31 2.92 0.147 93200 0.0649 1.64 0.968 0.014 1.07 0.0165 2550 PRS_PLINK_0.000199526231496888 TRUE 963 Poisoning by primarily systemic agents Both 19 198 18 injuries & poisonings gray50 198, 19 49, 5 49, 3 49, 9 50, 2 -0.0829 0.234 0.723 0.141 0.92 0.565 1.49 -0.663 0.714 0.354 0.451 0.515 0.103 2.16 0.623 0.577 0.281 0.552 1.86 0.612 6.27 -0.76 0.837 0.364 0.439 0.468 0.0597 2.55 PRS_PLINK_0.000199526231496888 TRUE 963.1 Antineoplastic and immunosuppressive drugs causing adverse effects Both 18 190 18 injuries & poisonings gray50 190, 18 47, 5 47, 3 47, 8 48, 2 -0.0716 0.238 0.764 0.117 0.931 0.565 1.52 -0.666 0.712 0.35 0.456 0.514 0.104 2.14 0.523 0.592 0.377 0.423 1.69 0.535 5.82 -0.689 0.843 0.414 0.383 0.502 0.0644 2.76 PRS_PLINK_0.000199526231496888 TRUE 964 Poisoning by agents primarily affecting blood constituents Both 6 51 18 injuries & poisonings gray50 51, 6 12, 5 13, 1 12, 0 13, 0 -0.751 0.522 0.15 0.824 0.472 0.0542 1.18 -0.955 1.33 0.474 0.325 0.385 0.00124 4.71 -2.39 1.93 0.217 0.664 0.092 0.0688 3.2 -1.73 1.43 0.225 0.649 0.176 0.00453 2.16 PRS_PLINK_0.000199526231496888 TRUE 964.1 Anticoagulants causing adverse effects Both 6 50 18 injuries & poisonings gray50 50, 6 12, 5 12, 1 12, 0 13, 0 -0.737 0.516 0.153 0.814 0.479 0.0533 1.18 -0.939 1.39 0.499 0.302 0.391 0.000666 5.31 -1.61 1.56 0.303 0.519 0.2 1.29e-05 4.66 -1.84 1.54 0.232 0.634 0.159 3.35e-05 2.3 PRS_PLINK_0.000199526231496888 TRUE 965 Poisoning by analgesics, antipyretics, and antirheumatics Both 11 71 18 injuries & poisonings gray50 71, 11 18, 3 18, 2 17, 3 18, 3 0.15 0.351 0.668 0.175 1.16 0.592 2.49 0.98 1.73 0.571 0.243 2.66 0.0688 111000 0.858 1.01 0.396 0.402 2.36 0.364 24.8 0.831 1.19 0.486 0.313 2.3 0.252 39.4 PRS_PLINK_0.000199526231496888 TRUE 965.1 Opiates and related narcotics causing adverse effects in therapeutic use Both 18 131 18 injuries & poisonings gray50 131, 18 33, 5 33, 2 32, 5 33, 6 0.103 0.251 0.682 0.167 1.11 0.678 1.85 -1.16 0.862 0.179 0.748 0.314 0.0429 1.63 0.016 0.653 0.98 0.009 1.02 0.276 3.67 0.0845 0.696 0.903 0.044 1.09 0.276 4.44 PRS_PLINK_0.000199526231496888 TRUE 965.3 Salicylates causing adverse effects in therapeutic use Both 1 8 18 injuries & poisonings gray50 8, 1 2, 0 2, 0 2, 1 2, 0 0.43 6.72 0.949 0.023 1.54 1.5 1.58 0.304 2490 1 0 1.36 0.548 2.19 PRS_PLINK_0.000199526231496888 TRUE 966 Poisoning by anticonvulsants and anti-Parkinsonism drugs Both 1 11 18 injuries & poisonings gray50 11, 1 3, 0 3, 0 2, 1 3, 0 1.26 3.58 0.725 0.14 3.53 0.0218 2960 0.849 879 0.999 0 2.34 2.95e-05 76500 PRS_PLINK_0.000199526231496888 TRUE 967 Adverse effects of sedatives or other central nervous system depressants and anesthetics Both 25 127 18 injuries & poisonings gray50 127, 25 32, 6 32, 5 31, 4 32, 10 0.185 0.239 0.44 0.356 1.2 0.756 1.93 0.013 0.654 0.984 0.007 1.01 0.273 3.75 -0.672 0.756 0.374 0.428 0.511 0.106 2.2 0.487 0.62 0.432 0.364 1.63 0.514 5.5 PRS_PLINK_0.000199526231496888 TRUE 969 Poisoning by psychotropic agents Both 4 37 18 injuries & poisonings gray50 37, 4 10, 1 9, 1 9, 0 9, 2 -0.275 0.536 0.607 0.217 0.759 0.11 2.33 0.199 1.32 0.88 0.055 1.22 0.0249 206 0.308 1.64 0.851 0.07 1.36 0.00942 4020 -0.414 1.63 0.799 0.097 0.661 0.000107 9.95 PRS_PLINK_0.000199526231496888 TRUE 971 Poisoning by drugs primarily affecting the autonomic nervous system Both 1 6 18 injuries & poisonings gray50 6, 1 2, 0 1, 1 1, 0 2, 0 -0.0598 1570 1 0 0.942 0.438 1.47 9.93e-05 3950 1 0 1 0.17 5.4 PRS_PLINK_0.000199526231496888 TRUE 972 Poisoning by agents primarily affecting the cardiovascular system Both 3 18 18 injuries & poisonings gray50 18, 3 5, 0 4, 1 4, 2 5, 0 1.53 1.78 0.391 0.407 4.6 0.235 124000 -0.972 9.45 0.918 0.037 0.379 0.353 0.408 0.962 4.2 0.819 0.087 2.62 0.00351 279000 PRS_PLINK_0.000199526231496888 TRUE 972.1 Cardiac rhythm regulators causing adverse effects in therapeutic use Both 0 1 18 injuries & poisonings gray50 1, 0 PRS_PLINK_0.000199526231496888 TRUE 972.6 Antihypertensive agents causing adverse effects Both 1 4 18 injuries & poisonings gray50 4, 1 1, 0 1, 0 1, 0 1, 1 -0.0401 1870 1 0 0.961 0.301 2.25 0.0127 173 1 0 1.01 0.71 1.39 PRS_PLINK_0.000199526231496888 TRUE 974 Poisoning by water, mineral, and uric acid metabolism drugs Both 2 6 18 injuries & poisonings gray50 6, 2 2, 1 1, 0 1, 1 2, 0 -0.0676 6270000 1 0 0.935 0.43 1.82 -0.535 54200 1 0 0.586 0.00447 8.78 -0.0863 6180 1 0 0.917 0.304 2.52 -1.23 4130 1 0 0.292 0.004 33.8 PRS_PLINK_0.000199526231496888 TRUE 975 Poisoning by agents primarily acting on the smooth and skeletal muscles and respiratory system Both 3 10 18 injuries & poisonings gray50 10, 3 3, 0 2, 2 2, 0 3, 1 -1.36 1.72 0.431 0.365 0.257 0.00117 3.03 0.204 6840000 1 0 1.23 0.118 72.2 -0.0671 1830 1 0 0.935 4.52 5.4 PRS_PLINK_0.000199526231496888 TRUE 976 Poisoning by agents primarily affecting skin & mucous membrane, ophthalmological, otorhinolaryngological, & dental drugs Both 1 1 18 injuries & poisonings gray50 1, 1 -0.0261 292 1 0 0.974 0.524 14.4 PRS_PLINK_0.000199526231496888 TRUE 977 Personal history of allergy to medicinal agents Both 20 133 18 injuries & poisonings gray50 133, 20 34, 6 33, 2 33, 6 33, 6 0.106 0.243 0.663 0.179 1.11 0.682 1.81 -0.807 0.73 0.269 0.57 0.446 0.0821 1.78 0.00726 0.621 0.991 0.004 1.01 0.287 3.43 0.252 0.618 0.683 0.166 1.29 0.38 4.51 PRS_PLINK_0.000199526231496888 TRUE 979 Adverse drug events and drug allergies Both 56 281 18 injuries & poisonings gray50 281, 56 70, 13 70, 12 70, 18 70, 13 0.127 0.164 0.441 0.356 1.13 0.823 1.58 -0.047 0.452 0.917 0.038 0.954 0.386 2.32 0.316 0.41 0.442 0.355 1.37 0.621 3.11 0.198 0.442 0.654 0.185 1.22 0.513 2.93 PRS_PLINK_0.000199526231496888 FALSE 980 Encounter for long-term (current) use of antibiotics Both 14 95 1 infectious diseases blue 95, 14 24, 5 24, 2 23, 5 24, 2 -0.189 0.284 0.505 0.297 0.827 0.465 1.45 -1.59 1.18 0.179 0.746 0.204 0.0115 1.92 0.124 0.748 0.868 0.061 1.13 0.267 5.28 -0.761 0.874 0.384 0.416 0.467 0.0599 2.5 PRS_PLINK_0.000199526231496888 TRUE 985 Toxic effect of other metals Both 0 5 18 injuries & poisonings gray50 5, 0 2 1 1 1 PRS_PLINK_0.000199526231496888 TRUE 989 Toxic effect of other substances, chiefly nonmedicinal as to source Both 3 11 18 injuries & poisonings gray50 11, 3 3, 2 3, 0 2, 1 3, 0 -0.721 0.741 0.331 0.481 0.486 0.0773 1.59 -0.215 103 0.998 0.001 0.807 0.27 0.969 -0.526 723 0.999 0 0.591 0.0911 1.15 -0.116 1290 1 0 0.891 0.577 1.7 PRS_PLINK_0.000199526231496888 TRUE 990 Effects radiation NOS Both 15 227 18 injuries & poisonings gray50 227, 15 56, 4 57, 3 56, 5 57, 3 -0.0495 0.258 0.848 0.072 0.952 0.554 1.63 -0.311 0.697 0.655 0.183 0.733 0.151 3.2 0.392 0.704 0.578 0.238 1.48 0.348 7.23 -0.219 0.95 0.817 0.088 0.803 0.101 6.8 PRS_PLINK_0.000199526231496888 TRUE 994 Sepsis and SIRS Both 27 144 18 injuries & poisonings gray50 144, 27 36, 8 36, 8 36, 6 36, 5 -0.231 0.216 0.286 0.544 0.794 0.515 1.21 0.015 0.561 0.979 0.009 1.02 0.335 3.06 -0.324 0.605 0.592 0.228 0.723 0.209 2.33 -0.332 0.651 0.61 0.215 0.717 0.189 2.51 PRS_PLINK_0.000199526231496888 TRUE 994.1 Systemic inflammatory response syndrome (SIRS) Both 4 38 18 injuries & poisonings gray50 38, 4 10, 0 9, 2 9, 0 10, 2 -0.205 0.536 0.701 0.154 0.814 0.223 2.33 1.66 1.81 0.359 0.444 5.24 0.152 30800 1.65 2.04 0.421 0.376 5.18 0.13 42700 PRS_PLINK_0.000199526231496888 TRUE 994.2 Sepsis Both 26 129 18 injuries & poisonings gray50 129, 26 33, 8 32, 8 32, 6 32, 4 -0.224 0.218 0.305 0.516 0.8 0.517 1.22 0.0196 0.566 0.972 0.012 1.02 0.337 3.08 -0.239 0.621 0.7 0.155 0.787 0.224 2.61 -0.415 0.652 0.524 0.281 0.66 0.172 2.31 PRS_PLINK_0.000199526231496888 TRUE 994.21 Septic shock Both 3 31 18 injuries & poisonings gray50 31, 3 8, 0 8, 0 7, 1 8, 2 1.04 0.861 0.229 0.64 2.82 0.554 290 0.0593 1.95 0.976 0.011 1.06 0.00288 947 1.53 3.13 0.626 0.204 4.6 0.0321 1.08e+08 PRS_PLINK_0.000199526231496888 TRUE