phewas_code phewas_string sex MatchedCases MatchedControls groupnum group color N N_Q1 N_Q2 N_Q3 N_Q4 PRS_BETA PRS_SEBETA PRS_P PRS_LOG10P PRS_OR PRS_CI1 PRS_CI2 Q1Q2_BETA Q1Q2_SEBETA Q1Q2_P Q1Q2_LOG10P Q1Q2_OR Q1Q2_CI1 Q1Q2_CI2 Q1Q3_BETA Q1Q3_SEBETA Q1Q3_P Q1Q3_LOG10P Q1Q3_OR Q1Q3_CI1 Q1Q3_CI2 Q1Q4_BETA Q1Q4_SEBETA Q1Q4_P Q1Q4_LOG10P Q1Q4_OR Q1Q4_CI1 Q1Q4_CI2 predictor exclude 008 Intestinal infection Both 613 3458 1 infectious diseases blue 3458, 613 864, 157 864, 161 864, 142 865, 153 -0.0163 0.0453 0.719 0.1432 0.984 0.9 1.08 0.0495 0.123 0.688 0.1622 1.05 0.825 1.34 -0.0937 0.129 0.466 0.3317 0.911 0.708 1.17 0.023 0.128 0.857 0.06685 1.02 0.796 1.32 PRS_PLINK_0.00398107170553497 FALSE 008.5 Bacterial enteritis Both 213 1491 1 infectious diseases blue 1491, 213 373, 50 373, 59 372, 48 373, 56 0.026 0.0754 0.73 0.1365 1.03 0.885 1.19 0.188 0.207 0.364 0.4393 1.21 0.805 1.81 0.027 0.221 0.903 0.04448 1.03 0.666 1.58 0.23 0.215 0.284 0.5469 1.26 0.826 1.92 PRS_PLINK_0.00398107170553497 FALSE 008.52 Intestinal infection due to C. difficile Both 151 1133 1 infectious diseases blue 1133, 151 284, 32 283, 42 283, 38 283, 39 0.0567 0.0884 0.521 0.2829 1.06 0.89 1.26 0.281 0.246 0.254 0.595 1.32 0.817 2.15 0.197 0.258 0.446 0.3505 1.22 0.734 2.02 0.291 0.257 0.257 0.5895 1.34 0.808 2.22 PRS_PLINK_0.00398107170553497 FALSE 008.6 Viral Enteritis Both 153 948 1 infectious diseases blue 948, 153 237, 41 237, 38 237, 33 237, 41 0.0475 0.0863 0.582 0.2351 1.05 0.885 1.24 -0.0651 0.248 0.793 0.1006 0.937 0.576 1.52 -0.141 0.254 0.579 0.2376 0.868 0.528 1.43 0.0639 0.252 0.8 0.09709 1.07 0.651 1.75 PRS_PLINK_0.00398107170553497 FALSE 010 Tuberculosis Both 27 271 1 infectious diseases blue 271, 27 68, 4 68, 9 67, 6 68, 8 0.341 0.216 0.114 0.9443 1.41 0.922 2.15 0.94 0.604 0.119 0.9231 2.56 0.784 8.36 0.615 0.632 0.331 0.48 1.85 0.535 6.39 0.769 0.635 0.226 0.6465 2.16 0.622 7.48 PRS_PLINK_0.00398107170553497 TRUE 031 Diseases due to other mycobacteria Both 24 118 1 infectious diseases blue 118, 24 30, 5 29, 9 29, 5 30, 5 -0.0224 0.262 0.932 0.03054 0.978 0.585 1.64 0.49 0.613 0.424 0.3727 1.63 0.491 5.42 0.511 0.803 0.525 0.28 1.67 0.345 8.05 -0.283 0.767 0.712 0.1477 0.753 0.168 3.38 PRS_PLINK_0.00398107170553497 TRUE 038 Septicemia Both 278 2448 1 infectious diseases blue 2448, 278 612, 78 612, 74 612, 61 612, 65 -0.0591 0.0642 0.358 0.4463 0.943 0.831 1.07 -0.044 0.172 0.798 0.09783 0.957 0.683 1.34 -0.258 0.182 0.156 0.8082 0.773 0.541 1.1 -0.195 0.181 0.283 0.5481 0.823 0.577 1.17 PRS_PLINK_0.00398107170553497 FALSE 038.1 Gram negative septicemia Both 62 541 1 infectious diseases blue 541, 62 136, 17 135, 16 135, 9 135, 20 0.0827 0.139 0.551 0.2586 1.09 0.828 1.43 -0.0287 0.358 0.936 0.0287 0.972 0.482 1.96 -0.558 0.412 0.176 0.7543 0.572 0.255 1.28 0.238 0.355 0.502 0.2995 1.27 0.633 2.55 PRS_PLINK_0.00398107170553497 FALSE 038.2 Gram positive septicemia Both 17 223 1 infectious diseases blue 223, 17 56, 8 56, 3 55, 1 56, 5 -0.226 0.241 0.348 0.4585 0.797 0.497 1.28 -0.85 0.679 0.21 0.6772 0.427 0.113 1.62 -1.36 0.829 0.101 0.9956 0.257 0.0505 1.3 -0.364 0.61 0.551 0.2591 0.695 0.21 2.3 PRS_PLINK_0.00398107170553497 TRUE 038.3 Bacteremia Both 120 1135 1 infectious diseases blue 1135, 120 284, 32 284, 30 283, 23 284, 35 0.0496 0.0965 0.607 0.2168 1.05 0.87 1.27 -0.0415 0.268 0.877 0.05703 0.959 0.568 1.62 -0.275 0.284 0.333 0.4781 0.76 0.436 1.32 0.195 0.266 0.464 0.3331 1.22 0.721 2.05 PRS_PLINK_0.00398107170553497 FALSE 041 Bacterial infection NOS Both 843 4149 1 infectious diseases blue 4149, 843 1038, 218 1037, 206 1037, 212 1037, 206 0.0063 0.0387 0.871 0.06015 1.01 0.933 1.09 -0.0395 0.108 0.713 0.1469 0.961 0.779 1.19 -0.00966 0.108 0.929 0.03206 0.99 0.801 1.22 -0.013 0.111 0.907 0.04244 0.987 0.794 1.23 PRS_PLINK_0.00398107170553497 FALSE 041.1 Staphylococcus infections Both 180 1642 1 infectious diseases blue 1642, 180 411, 50 410, 43 410, 40 411, 47 -0.0201 0.0811 0.804 0.09455 0.98 0.836 1.15 -0.13 0.22 0.555 0.256 0.878 0.571 1.35 -0.221 0.226 0.328 0.4843 0.802 0.515 1.25 -0.0199 0.22 0.928 0.03243 0.98 0.637 1.51 PRS_PLINK_0.00398107170553497 FALSE 041.11 Methicillin sensitive Staphylococcus aureus Both 86 864 1 infectious diseases blue 864, 86 216, 27 216, 17 216, 18 216, 24 -0.0586 0.115 0.61 0.2146 0.943 0.753 1.18 -0.455 0.318 0.152 0.8186 0.634 0.34 1.18 -0.434 0.319 0.174 0.7603 0.648 0.347 1.21 -0.0593 0.303 0.845 0.07325 0.942 0.52 1.71 PRS_PLINK_0.00398107170553497 FALSE 041.12 Methicillin resistant Staphylococcus aureus Both 77 773 1 infectious diseases blue 773, 77 194, 26 193, 16 193, 18 193, 17 -0.18 0.126 0.152 0.8191 0.835 0.653 1.07 -0.414 0.33 0.209 0.6792 0.661 0.346 1.26 -0.337 0.326 0.301 0.5215 0.714 0.377 1.35 -0.334 0.334 0.317 0.4985 0.716 0.373 1.38 PRS_PLINK_0.00398107170553497 FALSE 041.2 Streptococcus infection Both 199 1692 1 infectious diseases blue 1692, 199 423, 55 423, 48 423, 49 423, 47 -0.0597 0.0754 0.429 0.3677 0.942 0.813 1.09 -0.114 0.208 0.584 0.2336 0.892 0.594 1.34 -0.0624 0.211 0.767 0.115 0.94 0.621 1.42 -0.175 0.215 0.416 0.3812 0.839 0.551 1.28 PRS_PLINK_0.00398107170553497 FALSE 041.21 Rheumatic fever / chorea Both 40 311 1 infectious diseases blue 311, 40 78, 8 78, 14 77, 9 78, 9 0.0336 0.175 0.848 0.07157 1.03 0.733 1.46 0.643 0.453 0.155 0.8085 1.9 0.783 4.62 0.321 0.514 0.532 0.2743 1.38 0.504 3.78 -0.111 0.52 0.831 0.08063 0.895 0.323 2.48 PRS_PLINK_0.00398107170553497 TRUE 041.4 E. coli Both 199 1438 1 infectious diseases blue 1438, 199 360, 51 359, 42 359, 51 360, 55 0.0775 0.0784 0.323 0.4914 1.08 0.927 1.26 -0.154 0.222 0.487 0.3127 0.857 0.555 1.32 -0.00723 0.213 0.973 0.01191 0.993 0.654 1.51 0.0979 0.215 0.648 0.1883 1.1 0.724 1.68 PRS_PLINK_0.00398107170553497 FALSE 041.8 H. pylori Both 45 352 1 infectious diseases blue 352, 45 88, 13 88, 13 88, 8 88, 11 -0.0826 0.159 0.603 0.2196 0.921 0.674 1.26 -0.02 0.411 0.961 0.01719 0.98 0.438 2.19 -0.626 0.47 0.183 0.7371 0.535 0.213 1.34 -0.235 0.43 0.585 0.2328 0.791 0.34 1.84 PRS_PLINK_0.00398107170553497 TRUE 041.9 Infection with drug-resistant microorganisms Both 39 409 1 infectious diseases blue 409, 39 103, 11 102, 10 102, 8 102, 10 -0.0759 0.176 0.666 0.1766 0.927 0.657 1.31 -0.136 0.45 0.762 0.1178 0.873 0.362 2.11 -0.319 0.473 0.5 0.301 0.727 0.288 1.84 -0.228 0.477 0.632 0.199 0.796 0.313 2.03 PRS_PLINK_0.00398107170553497 TRUE 053 Herpes zoster Both 399 1480 1 infectious diseases blue 1480, 399 370, 103 370, 102 370, 92 370, 102 -0.0326 0.0581 0.575 0.2407 0.968 0.864 1.08 -0.0418 0.162 0.796 0.09931 0.959 0.699 1.32 -0.132 0.167 0.428 0.3681 0.876 0.631 1.22 -0.0201 0.167 0.904 0.04363 0.98 0.706 1.36 PRS_PLINK_0.00398107170553497 FALSE 053.1 Herpes zoster with nervous system complications Both 55 226 1 infectious diseases blue 226, 55 57, 19 56, 12 56, 16 57, 8 -0.485 0.176 0.0058 2.237 0.616 0.436 0.869 -0.841 0.463 0.0691 1.161 0.431 0.174 1.07 -0.417 0.422 0.323 0.4907 0.659 0.289 1.51 -1.32 0.546 0.0153 1.817 0.266 0.0912 0.775 PRS_PLINK_0.00398107170553497 FALSE 054 Herpes simplex Both 426 1548 1 infectious diseases blue 1548, 426 387, 107 387, 116 387, 99 387, 103 0.0339 0.0571 0.553 0.257 1.03 0.925 1.16 0.062 0.156 0.691 0.1605 1.06 0.784 1.44 -0.114 0.162 0.484 0.3153 0.893 0.649 1.23 0.0438 0.165 0.791 0.102 1.04 0.756 1.44 PRS_PLINK_0.00398107170553497 FALSE 070 Viral hepatitis Both 92 586 1 infectious diseases blue 586, 92 147, 20 146, 23 146, 20 147, 29 0.121 0.12 0.312 0.5063 1.13 0.893 1.43 0.174 0.321 0.588 0.2307 1.19 0.634 2.24 0.0247 0.339 0.942 0.02605 1.03 0.528 1.99 0.482 0.327 0.14 0.8539 1.62 0.854 3.07 PRS_PLINK_0.00398107170553497 FALSE 070.1 Viral hepatitis A Both 13 73 1 infectious diseases blue 73, 13 19, 1 18, 4 18, 4 18, 4 0.263 0.349 0.451 0.3462 1.3 0.657 2.58 0.601 1.04 0.564 0.2488 1.82 0.237 14 1.17 1.05 0.267 0.573 3.22 0.408 25.4 1.01 1.05 0.336 0.4742 2.74 0.353 21.2 PRS_PLINK_0.00398107170553497 TRUE 070.2 Viral hepatitis B Both 30 166 1 infectious diseases blue 166, 30 42, 10 41, 10 41, 5 42, 5 -0.269 0.196 0.17 0.7708 0.764 0.52 1.12 0.0782 0.504 0.877 0.05719 1.08 0.403 2.9 -0.556 0.566 0.326 0.4871 0.573 0.189 1.74 -0.678 0.584 0.246 0.6087 0.508 0.162 1.6 PRS_PLINK_0.00398107170553497 TRUE 070.3 Viral hepatitis C Both 45 346 1 infectious diseases blue 346, 45 87, 10 86, 8 86, 11 87, 16 0.294 0.176 0.0957 1.019 1.34 0.949 1.9 -0.0811 0.488 0.868 0.06145 0.922 0.354 2.4 0.0805 0.459 0.861 0.06512 1.08 0.441 2.66 0.637 0.437 0.145 0.8401 1.89 0.804 4.45 PRS_PLINK_0.00398107170553497 TRUE 070.4 Chronic hepatitis Both 28 147 1 infectious diseases blue 147, 28 37, 8 37, 2 36, 11 37, 7 0.0475 0.205 0.817 0.08771 1.05 0.701 1.57 -1.46 0.828 0.0788 1.104 0.233 0.0461 1.18 0.0346 0.595 0.954 0.0206 1.04 0.322 3.32 -0.0125 0.648 0.985 0.006761 0.988 0.277 3.52 PRS_PLINK_0.00398107170553497 TRUE 070.9 Hepatitis NOS Both 156 877 1 infectious diseases blue 877, 156 220, 41 219, 42 219, 27 219, 46 -0.0112 0.0912 0.902 0.04473 0.989 0.827 1.18 0.108 0.242 0.657 0.1824 1.11 0.693 1.79 -0.429 0.277 0.122 0.9126 0.651 0.378 1.12 0.13 0.242 0.591 0.2285 1.14 0.708 1.83 PRS_PLINK_0.00398107170553497 FALSE 071 Human immunodeficiency virus [HIV] disease Both 15 79 1 infectious diseases blue 79, 15 20, 3 20, 4 19, 6 20, 2 0.0594 0.311 0.848 0.07139 1.06 0.577 1.95 0.226 0.805 0.779 0.1085 1.25 0.259 6.07 0.667 0.81 0.41 0.387 1.95 0.398 9.53 -0.416 0.886 0.639 0.1947 0.66 0.116 3.74 PRS_PLINK_0.00398107170553497 TRUE 071.1 HIV infection, symptomatic Both 14 56 1 infectious diseases blue 56, 14 14, 3 14, 5 14, 4 14, 2 0.0326 0.37 0.93 0.03162 1.03 0.5 2.13 -0.749 1.09 0.491 0.3085 0.473 0.056 3.99 0.667 1.02 0.512 0.2904 1.95 0.265 14.3 -0.137 1.43 0.924 0.03449 0.872 0.0528 14.4 PRS_PLINK_0.00398107170553497 TRUE 078 Viral warts & HPV Both 841 2514 1 infectious diseases blue 2514, 841 629, 211 628, 202 628, 203 629, 225 0.049 0.0409 0.231 0.6356 1.05 0.969 1.14 -0.0272 0.115 0.814 0.08958 0.973 0.776 1.22 0.00312 0.116 0.979 0.009397 1 0.799 1.26 0.0876 0.116 0.451 0.3459 1.09 0.869 1.37 PRS_PLINK_0.00398107170553497 FALSE 079 Viral infection Both 1568 2771 1 infectious diseases blue 2771, 1568 693, 410 693, 421 692, 376 693, 361 -0.03 0.0329 0.361 0.4423 0.97 0.91 1.04 0.0272 0.0897 0.762 0.1182 1.03 0.862 1.23 -0.0709 0.0924 0.443 0.3536 0.932 0.777 1.12 -0.0933 0.0943 0.322 0.492 0.911 0.757 1.1 PRS_PLINK_0.00398107170553497 FALSE 079.1 Varicella infection Both 1011 2649 1 infectious diseases blue 2649, 1011 663, 266 662, 270 662, 251 662, 224 -0.0498 0.0388 0.199 0.7007 0.951 0.882 1.03 -0.0123 0.105 0.907 0.04243 0.988 0.804 1.21 -0.0418 0.107 0.697 0.1567 0.959 0.777 1.18 -0.14 0.111 0.206 0.6858 0.869 0.699 1.08 PRS_PLINK_0.00398107170553497 FALSE 079.2 Infectious mononucleosis Both 39 228 1 infectious diseases blue 228, 39 57, 11 57, 11 57, 10 57, 7 -0.308 0.193 0.11 0.9582 0.735 0.504 1.07 -0.207 0.485 0.67 0.174 0.813 0.314 2.1 -0.399 0.507 0.431 0.3655 0.671 0.248 1.81 -0.712 0.554 0.199 0.7009 0.491 0.166 1.45 PRS_PLINK_0.00398107170553497 TRUE 079.9 Viremia, NOS Both 172 730 1 infectious diseases blue 730, 172 183, 55 182, 51 182, 30 183, 36 -0.21 0.0889 0.0179 1.747 0.81 0.681 0.964 -0.101 0.23 0.661 0.1798 0.904 0.576 1.42 -0.599 0.258 0.02 1.7 0.549 0.331 0.91 -0.457 0.248 0.0652 1.186 0.633 0.39 1.03 PRS_PLINK_0.00398107170553497 FALSE 080 Postoperative infection Both 269 2968 1 infectious diseases blue 2968, 269 742, 57 742, 64 742, 69 742, 79 0.124 0.0654 0.0571 1.243 1.13 0.996 1.29 0.112 0.188 0.551 0.2589 1.12 0.774 1.62 0.216 0.188 0.251 0.6005 1.24 0.858 1.79 0.345 0.186 0.0634 1.198 1.41 0.981 2.03 PRS_PLINK_0.00398107170553497 FALSE 081 Infection/inflammation of internal prosthetic device; implant; and graft Both 170 1651 1 infectious diseases blue 1651, 170 413, 36 413, 41 412, 44 413, 49 0.133 0.0817 0.103 0.9875 1.14 0.973 1.34 0.137 0.236 0.562 0.2504 1.15 0.722 1.82 0.213 0.237 0.369 0.4327 1.24 0.777 1.97 0.324 0.234 0.165 0.7824 1.38 0.875 2.19 PRS_PLINK_0.00398107170553497 FALSE 090 Sexually transmitted infections (not HIV or hepatitis) Both 206 1202 1 infectious diseases blue 1202, 206 301, 53 300, 56 300, 52 301, 45 0.0214 0.0768 0.78 0.1077 1.02 0.879 1.19 0.0751 0.211 0.722 0.1413 1.08 0.713 1.63 -0.0617 0.217 0.776 0.1099 0.94 0.614 1.44 -0.184 0.227 0.419 0.378 0.832 0.533 1.3 PRS_PLINK_0.00398107170553497 FALSE 110 Dermatophytosis / Dermatomycosis Both 791 3037 1 infectious diseases blue 3037, 791 760, 216 759, 185 759, 189 759, 200 -0.0411 0.0412 0.319 0.4959 0.96 0.885 1.04 -0.137 0.114 0.228 0.6419 0.872 0.697 1.09 -0.138 0.115 0.229 0.6395 0.871 0.695 1.09 -0.125 0.115 0.279 0.5547 0.883 0.705 1.11 PRS_PLINK_0.00398107170553497 FALSE 110.1 Dermatophytosis Both 724 2781 1 infectious diseases blue 2781, 724 696, 200 695, 169 695, 169 695, 185 -0.0416 0.0433 0.337 0.4721 0.959 0.881 1.04 -0.159 0.119 0.183 0.7382 0.853 0.676 1.08 -0.176 0.12 0.144 0.8425 0.839 0.662 1.06 -0.117 0.12 0.328 0.4844 0.889 0.703 1.12 PRS_PLINK_0.00398107170553497 FALSE 110.11 Dermatophytosis of nail Both 464 1862 1 infectious diseases blue 1862, 464 466, 133 465, 104 465, 117 466, 109 -0.0763 0.0544 0.16 0.7952 0.927 0.833 1.03 -0.24 0.148 0.106 0.9746 0.787 0.588 1.05 -0.112 0.146 0.442 0.3542 0.894 0.672 1.19 -0.228 0.15 0.129 0.8899 0.796 0.593 1.07 PRS_PLINK_0.00398107170553497 FALSE 110.12 Althete's foot Both 174 833 1 infectious diseases blue 833, 174 209, 52 208, 33 208, 34 208, 55 -0.0293 0.0871 0.736 0.1329 0.971 0.819 1.15 -0.457 0.247 0.0639 1.194 0.633 0.391 1.03 -0.538 0.252 0.0326 1.487 0.584 0.357 0.956 -0.0494 0.229 0.829 0.08132 0.952 0.607 1.49 PRS_PLINK_0.00398107170553497 FALSE 110.13 Dermatophytosis of the body Both 156 718 1 infectious diseases blue 718, 156 180, 39 179, 47 179, 35 180, 35 -0.00827 0.093 0.929 0.03193 0.992 0.827 1.19 0.184 0.247 0.455 0.3419 1.2 0.741 1.95 -0.0908 0.263 0.73 0.1366 0.913 0.545 1.53 -0.0668 0.269 0.804 0.09479 0.935 0.552 1.58 PRS_PLINK_0.00398107170553497 FALSE 110.2 Dermatomycoses Both 86 425 1 infectious diseases blue 425, 86 107, 23 106, 17 106, 20 106, 26 0.0358 0.124 0.773 0.1116 1.04 0.812 1.32 -0.236 0.361 0.513 0.2903 0.789 0.389 1.6 -0.169 0.353 0.633 0.1985 0.845 0.423 1.69 -0.00423 0.344 0.99 0.004279 0.996 0.507 1.95 PRS_PLINK_0.00398107170553497 FALSE 112 Candidiasis Both 670 3412 1 infectious diseases blue 3412, 670 853, 191 853, 183 853, 141 853, 155 -0.0558 0.0435 0.2 0.6989 0.946 0.868 1.03 -0.0015 0.116 0.99 0.004521 0.998 0.796 1.25 -0.287 0.123 0.0197 1.706 0.75 0.589 0.955 -0.159 0.122 0.19 0.7202 0.853 0.672 1.08 PRS_PLINK_0.00398107170553497 FALSE 112.3 Candidiasis of skin and nails Both 109 877 1 infectious diseases blue 877, 109 220, 30 219, 28 219, 19 219, 32 0.0329 0.106 0.756 0.1215 1.03 0.84 1.27 -0.102 0.278 0.713 0.1467 0.903 0.523 1.56 -0.573 0.308 0.0622 1.206 0.564 0.308 1.03 -0.0783 0.276 0.777 0.1096 0.925 0.538 1.59 PRS_PLINK_0.00398107170553497 FALSE 117 Mycoses Both 92 602 1 infectious diseases blue 602, 92 151, 35 150, 18 150, 24 151, 15 -0.205 0.118 0.0831 1.08 0.815 0.647 1.03 -0.55 0.311 0.0768 1.114 0.577 0.314 1.06 -0.316 0.298 0.289 0.5397 0.729 0.407 1.31 -0.694 0.33 0.0354 1.451 0.5 0.262 0.954 PRS_PLINK_0.00398107170553497 FALSE 117.1 Histoplasmosis Both 17 97 1 infectious diseases blue 97, 17 25, 7 24, 1 24, 6 24, 3 -0.172 0.293 0.558 0.2534 0.842 0.474 1.5 -1.73 1.07 0.107 0.9714 0.178 0.0219 1.45 -0.266 0.66 0.686 0.1634 0.766 0.21 2.79 -0.518 0.754 0.492 0.308 0.596 0.136 2.61 PRS_PLINK_0.00398107170553497 TRUE 117.4 Aspergillosis Both 23 135 1 infectious diseases blue 135, 23 34, 6 34, 6 33, 8 34, 3 -0.219 0.246 0.374 0.427 0.804 0.496 1.3 0.01 0.647 0.988 0.005403 1.01 0.284 3.59 0.0453 0.638 0.943 0.02533 1.05 0.3 3.65 -0.834 0.79 0.291 0.5357 0.435 0.0924 2.04 PRS_PLINK_0.00398107170553497 TRUE 130 Spirochetal infection Both 41 188 1 infectious diseases blue 188, 41 47, 11 47, 7 47, 11 47, 12 0.0924 0.184 0.615 0.2115 1.1 0.765 1.57 -0.433 0.546 0.428 0.3683 0.649 0.222 1.89 0.0508 0.51 0.921 0.0359 1.05 0.387 2.86 -0.57 0.563 0.311 0.5073 0.565 0.188 1.7 PRS_PLINK_0.00398107170553497 TRUE 130.1 Lyme disease Both 31 150 1 infectious diseases blue 150, 31 38, 10 37, 7 37, 10 38, 4 -0.231 0.201 0.25 0.6016 0.794 0.535 1.18 -0.444 0.545 0.415 0.382 0.641 0.22 1.87 0.245 0.561 0.662 0.1791 1.28 0.426 3.84 -1.1 0.686 0.108 0.9681 0.331 0.0863 1.27 PRS_PLINK_0.00398107170553497 TRUE 131 Protozoan infection Both 13 92 1 infectious diseases blue 92, 13 23, 3 23, 3 23, 3 23, 4 0.0732 0.323 0.821 0.08573 1.08 0.571 2.03 -0.916 1.06 0.389 0.4097 0.4 0.0497 3.22 0.299 0.749 0.689 0.1616 1.35 0.311 5.85 PRS_PLINK_0.00398107170553497 TRUE 132 Infestation (lice, mites) Both 35 222 1 infectious diseases blue 222, 35 56, 8 55, 11 55, 10 56, 6 -0.0509 0.192 0.791 0.102 0.95 0.652 1.38 0.419 0.5 0.402 0.3961 1.52 0.571 4.05 0.45 0.563 0.424 0.3722 1.57 0.52 4.73 -0.185 0.616 0.764 0.1167 0.831 0.248 2.78 PRS_PLINK_0.00398107170553497 TRUE 134 Helminthiases Both 23 97 1 infectious diseases blue 97, 23 25, 5 24, 5 24, 4 24, 9 0.152 0.268 0.572 0.2429 1.16 0.688 1.97 -0.047 0.749 0.95 0.02232 0.954 0.22 4.14 0.385 0.885 0.664 0.178 1.47 0.259 8.32 0.437 0.665 0.511 0.2918 1.55 0.421 5.7 PRS_PLINK_0.00398107170553497 TRUE 134.1 Intestinal helminthiases Both 16 63 1 infectious diseases blue 63, 16 16, 5 16, 3 15, 2 16, 6 -0.0673 0.319 0.833 0.07935 0.935 0.5 1.75 -0.246 0.824 0.765 0.1164 0.782 0.156 3.93 -0.476 1.01 0.639 0.1946 0.621 0.0851 4.54 -0.0354 0.817 0.965 0.01527 0.965 0.194 4.79 PRS_PLINK_0.00398107170553497 TRUE 136 Other infectious and parasitic diseases Both 558 3682 1 infectious diseases blue 3682, 558 920, 142 920, 149 920, 130 921, 137 -0.0134 0.0462 0.772 0.1123 0.987 0.901 1.08 0.0436 0.127 0.731 0.1364 1.04 0.815 1.34 -0.0956 0.132 0.468 0.3297 0.909 0.702 1.18 -0.0478 0.132 0.718 0.144 0.953 0.736 1.24 PRS_PLINK_0.00398107170553497 FALSE 145 Cancer of mouth Both 76 1363 2 neoplasms darkcyan 1363, 76 340, 19 341, 18 340, 23 341, 16 -0.051 0.119 0.669 0.1745 0.95 0.752 1.2 0.07 0.331 0.833 0.07952 1.07 0.56 2.05 0.217 0.321 0.499 0.3016 1.24 0.662 2.33 0.0326 0.357 0.927 0.0328 1.03 0.513 2.08 PRS_PLINK_0.00398107170553497 FALSE 145.1 Cancer of lip Both 3 65 2 neoplasms darkcyan 65, 3 17, 1 16, 1 16, 0 16, 1 -0.328 0.583 0.573 0.2417 0.72 0.23 2.26 0.374 1.53 0.806 0.09341 1.45 0.0729 29 -0.0347 1.24 0.978 0.009835 0.966 0.0856 10.9 0.452 1.34 0.736 0.1334 1.57 0.114 21.7 PRS_PLINK_0.00398107170553497 TRUE 145.2 Cancer of tongue Both 34 528 2 neoplasms darkcyan 528, 34 131, 7 132, 9 132, 11 132, 7 -0.0126 0.178 0.944 0.02521 0.988 0.697 1.4 0.287 0.503 0.568 0.2453 1.33 0.497 3.57 0.246 0.485 0.612 0.2133 1.28 0.494 3.31 0.0632 0.534 0.906 0.04293 1.07 0.374 3.04 PRS_PLINK_0.00398107170553497 TRUE 145.3 Cancer of major salivary glands Both 17 342 2 neoplasms darkcyan 342, 17 86, 5 85, 4 85, 6 86, 2 -0.0874 0.222 0.693 0.1591 0.916 0.593 1.41 -0.294 0.61 0.629 0.2012 0.745 0.225 2.46 0.338 0.636 0.595 0.2254 1.4 0.403 4.88 -0.493 0.684 0.472 0.3264 0.611 0.16 2.34 PRS_PLINK_0.00398107170553497 TRUE 145.4 Cancer of the gums Both 3 204 2 neoplasms darkcyan 204, 3 51, 2 51, 0 51, 0 51, 1 -0.434 0.382 0.257 0.5902 0.648 0.306 1.37 -1.43 1.2 0.233 0.6332 0.239 0.0228 2.51 -1.06 1.22 0.386 0.4139 0.347 0.0319 3.79 -0.306 1.02 0.764 0.1171 0.736 0.1 5.42 PRS_PLINK_0.00398107170553497 TRUE 145.5 Cancer of the mouth floor Both 12 178 2 neoplasms darkcyan 178, 12 44, 1 44, 4 44, 5 45, 2 0.0303 0.297 0.919 0.03683 1.03 0.576 1.85 1.4 1.04 0.177 0.753 4.06 0.532 30.9 0.995 1.09 0.362 0.4413 2.7 0.319 22.9 0.523 0.955 0.584 0.2336 1.69 0.259 11 PRS_PLINK_0.00398107170553497 TRUE 149 Cancer of larynx, pharynx, nasal cavities Both 80 1141 2 neoplasms darkcyan 1141, 80 285, 22 285, 18 285, 22 285, 18 -0.0405 0.118 0.73 0.1365 0.96 0.763 1.21 -0.164 0.321 0.609 0.2153 0.849 0.453 1.59 0.0137 0.314 0.965 0.01539 1.01 0.548 1.88 -0.0881 0.338 0.795 0.09985 0.916 0.472 1.78 PRS_PLINK_0.00398107170553497 FALSE 149.1 Cancer of oropharynx Both 29 255 2 neoplasms darkcyan 255, 29 64, 9 64, 2 63, 9 64, 9 0.2 0.201 0.319 0.496 1.22 0.824 1.81 -0.997 0.665 0.134 0.873 0.369 0.1 1.36 0.277 0.528 0.6 0.2217 1.32 0.468 3.71 0.169 0.529 0.749 0.1252 1.18 0.42 3.34 PRS_PLINK_0.00398107170553497 TRUE 149.2 Cancer of nasopharynx Both 11 109 2 neoplasms darkcyan 109, 11 28, 2 27, 4 27, 2 27, 3 -0.144 0.377 0.701 0.154 0.866 0.414 1.81 0.126 0.814 0.877 0.05697 1.13 0.23 5.59 0.0657 0.895 0.941 0.02622 1.07 0.185 6.17 -0.0853 0.852 0.92 0.03611 0.918 0.173 4.88 PRS_PLINK_0.00398107170553497 TRUE 149.3 Cancer of hypopharynx Both 8 71 2 neoplasms darkcyan 71, 8 18, 0 18, 3 17, 2 18, 3 0.494 0.389 0.205 0.6886 1.64 0.764 3.51 1.3 1.21 0.283 0.5489 3.66 0.343 39 0.643 1.23 0.601 0.221 1.9 0.171 21.2 1.15 1.26 0.361 0.4419 3.15 0.268 37.2 PRS_PLINK_0.00398107170553497 TRUE 149.4 Cancer of larynx Both 16 246 2 neoplasms darkcyan 246, 16 62, 3 61, 2 61, 7 62, 4 0.0987 0.257 0.7 0.1547 1.1 0.668 1.82 -0.738 0.812 0.363 0.4398 0.478 0.0973 2.35 0.116 0.685 0.866 0.06253 1.12 0.293 4.3 0.109 0.717 0.88 0.05566 1.11 0.273 4.55 PRS_PLINK_0.00398107170553497 TRUE 149.5 Hx of malignant neoplasm of oral cavity and pharynx Both 43 474 2 neoplasms darkcyan 474, 43 118, 9 118, 10 118, 12 119, 12 0.0947 0.165 0.566 0.2472 1.1 0.796 1.52 -0.0141 0.468 0.976 0.01057 0.986 0.394 2.47 0.232 0.451 0.607 0.2165 1.26 0.521 3.05 0.376 0.484 0.437 0.3596 1.46 0.564 3.76 PRS_PLINK_0.00398107170553497 TRUE 149.9 Cancer of of nasal cavities Both 14 264 2 neoplasms darkcyan 264, 14 66, 4 66, 3 66, 1 66, 6 0.122 0.256 0.633 0.1988 1.13 0.685 1.87 -0.00105 0.694 0.999 0.0005256 0.999 0.256 3.89 -0.933 0.803 0.245 0.6101 0.393 0.0815 1.9 0.319 0.671 0.634 0.1978 1.38 0.37 5.12 PRS_PLINK_0.00398107170553497 TRUE 150 Cancer of esophagus Both 29 315 2 neoplasms darkcyan 315, 29 79, 7 79, 5 78, 10 79, 7 -0.0298 0.192 0.877 0.05708 0.971 0.666 1.42 -0.0842 0.581 0.885 0.05317 0.919 0.295 2.87 0.226 0.517 0.662 0.1791 1.25 0.455 3.45 -0.145 0.564 0.797 0.09831 0.865 0.286 2.62 PRS_PLINK_0.00398107170553497 TRUE 151 Cancer of stomach Both 33 420 2 neoplasms darkcyan 420, 33 105, 12 105, 3 105, 7 105, 11 -0.0515 0.182 0.777 0.1094 0.95 0.665 1.36 -1.64 0.666 0.014 1.854 0.195 0.0528 0.718 -0.55 0.479 0.251 0.6 0.577 0.225 1.48 -0.231 0.445 0.603 0.2195 0.793 0.332 1.9 PRS_PLINK_0.00398107170553497 TRUE 153 Colorectal cancer Both 170 1121 2 neoplasms darkcyan 1121, 170 281, 43 280, 35 280, 39 280, 53 0.155 0.0864 0.0726 1.139 1.17 0.986 1.38 -0.149 0.243 0.539 0.2688 0.861 0.535 1.39 -0.0701 0.244 0.774 0.1111 0.932 0.578 1.5 0.31 0.23 0.177 0.753 1.36 0.87 2.14 PRS_PLINK_0.00398107170553497 FALSE 153.2 Colon cancer Both 136 853 2 neoplasms darkcyan 853, 136 214, 34 213, 24 213, 33 213, 45 0.184 0.0987 0.0619 1.208 1.2 0.991 1.46 -0.332 0.281 0.237 0.6245 0.717 0.413 1.24 -0.0849 0.271 0.754 0.1227 0.919 0.54 1.56 0.333 0.253 0.188 0.7268 1.4 0.85 2.29 PRS_PLINK_0.00398107170553497 FALSE 153.3 Malignant neoplasm of rectum, rectosigmoid junction, and anus Both 92 637 2 neoplasms darkcyan 637, 92 160, 26 159, 20 159, 21 159, 25 0.0346 0.117 0.768 0.1146 1.04 0.822 1.3 -0.306 0.317 0.335 0.4756 0.736 0.395 1.37 -0.198 0.319 0.535 0.272 0.82 0.439 1.53 0.0713 0.314 0.82 0.08612 1.07 0.581 1.99 PRS_PLINK_0.00398107170553497 FALSE 155 Cancer of liver and intrahepatic bile duct Both 36 475 2 neoplasms darkcyan 475, 36 119, 12 119, 4 118, 10 119, 10 -0.159 0.177 0.369 0.4331 0.853 0.602 1.21 -0.958 0.538 0.075 1.125 0.384 0.134 1.1 -0.345 0.445 0.438 0.3583 0.708 0.296 1.69 -0.297 0.465 0.522 0.282 0.743 0.299 1.85 PRS_PLINK_0.00398107170553497 TRUE 155.1 Malignant neoplasm of liver, primary Both 22 321 2 neoplasms darkcyan 321, 22 81, 7 80, 2 80, 5 80, 8 -0.171 0.221 0.44 0.357 0.843 0.546 1.3 -1.01 0.69 0.142 0.849 0.363 0.0939 1.4 -0.393 0.566 0.487 0.3127 0.675 0.223 2.04 -0.266 0.584 0.649 0.1876 0.767 0.244 2.41 PRS_PLINK_0.00398107170553497 TRUE 157 Pancreatic cancer Both 42 509 2 neoplasms darkcyan 509, 42 128, 12 127, 8 127, 10 127, 12 -0.133 0.168 0.426 0.3708 0.875 0.63 1.22 -0.565 0.45 0.21 0.6788 0.568 0.235 1.37 -0.336 0.447 0.453 0.3443 0.715 0.298 1.72 -0.126 0.427 0.769 0.1141 0.882 0.382 2.04 PRS_PLINK_0.00398107170553497 TRUE 158 Neoplasm of unspecified nature of digestive system Both 247 1650 2 neoplasms darkcyan 1650, 247 413, 71 412, 48 412, 60 413, 68 -0.0173 0.0697 0.804 0.09499 0.983 0.857 1.13 -0.365 0.2 0.0681 1.167 0.694 0.469 1.03 -0.127 0.193 0.511 0.2917 0.881 0.604 1.29 -0.0795 0.191 0.677 0.1695 0.924 0.635 1.34 PRS_PLINK_0.00398107170553497 FALSE 159 Malignant neoplasm of other and ill-defined sites within the digestive organs and peritoneum Both 178 1781 2 neoplasms darkcyan 1781, 178 446, 58 445, 32 445, 39 445, 49 -0.05 0.0818 0.541 0.2671 0.951 0.81 1.12 -0.591 0.228 0.00943 2.025 0.554 0.354 0.865 -0.432 0.219 0.0486 1.313 0.649 0.423 0.997 -0.165 0.209 0.428 0.3682 0.848 0.563 1.28 PRS_PLINK_0.00398107170553497 FALSE 159.2 Malignant neoplasm of small intestine, including duodenum Both 16 217 2 neoplasms darkcyan 217, 16 55, 4 54, 4 54, 4 54, 4 -0.0103 0.241 0.966 0.01503 0.99 0.617 1.59 -0.0774 0.651 0.905 0.04319 0.925 0.258 3.32 0.0429 0.651 0.947 0.02343 1.04 0.292 3.74 -0.265 0.669 0.692 0.1598 0.767 0.207 2.85 PRS_PLINK_0.00398107170553497 TRUE 159.3 Malignant neoplasm of gallbladder and extrahepatic bile ducts Both 8 176 2 neoplasms darkcyan 176, 8 44, 1 44, 2 44, 4 44, 1 0.0384 0.357 0.914 0.03888 1.04 0.516 2.09 1.4 1.14 0.219 0.6602 4.07 0.435 38.2 0.788 0.933 0.399 0.3995 2.2 0.353 13.7 -0.787 1.34 0.557 0.254 0.455 0.0328 6.31 PRS_PLINK_0.00398107170553497 TRUE 159.4 Malignant neoplasm of retroperitoneum and peritoneum Both 31 354 2 neoplasms darkcyan 354, 31 89, 10 88, 6 88, 10 89, 5 -0.143 0.185 0.441 0.3557 0.867 0.603 1.25 -0.519 0.526 0.324 0.4897 0.595 0.212 1.67 0.119 0.476 0.803 0.09546 1.13 0.443 2.86 -0.789 0.55 0.151 0.8206 0.454 0.155 1.33 PRS_PLINK_0.00398107170553497 TRUE 164 Cancer of intrathoracic organs Both 15 156 2 neoplasms darkcyan 156, 15 39, 4 39, 4 39, 2 39, 5 0.00524 0.262 0.984 0.006986 1.01 0.602 1.68 0.282 0.721 0.695 0.1578 1.33 0.323 5.45 -1.22 0.862 0.156 0.8064 0.295 0.0544 1.59 -0.555 0.783 0.478 0.3204 0.574 0.124 2.66 PRS_PLINK_0.00398107170553497 TRUE 165 Cancer within the respiratory system Both 107 1347 2 neoplasms darkcyan 1347, 107 337, 32 337, 19 336, 31 337, 24 -0.181 0.103 0.0772 1.112 0.834 0.682 1.02 -0.607 0.295 0.0392 1.407 0.545 0.306 0.97 -0.176 0.263 0.503 0.2981 0.839 0.501 1.4 -0.438 0.287 0.126 0.899 0.645 0.368 1.13 PRS_PLINK_0.00398107170553497 FALSE 165.1 Cancer of bronchus; lung Both 93 1105 2 neoplasms darkcyan 1105, 93 277, 28 276, 17 276, 27 276, 20 -0.179 0.111 0.108 0.9654 0.836 0.672 1.04 -0.602 0.313 0.0546 1.263 0.548 0.296 1.01 -0.157 0.28 0.577 0.2391 0.855 0.494 1.48 -0.442 0.305 0.147 0.8325 0.642 0.353 1.17 PRS_PLINK_0.00398107170553497 FALSE 170 Cancer of bone and connective tissue Both 124 1888 2 neoplasms darkcyan 1888, 124 472, 36 472, 30 472, 26 472, 32 -0.0168 0.0963 0.861 0.06493 0.983 0.814 1.19 -0.15 0.253 0.552 0.2581 0.86 0.524 1.41 -0.286 0.265 0.281 0.5508 0.752 0.447 1.26 -0.0384 0.257 0.881 0.05503 0.962 0.582 1.59 PRS_PLINK_0.00398107170553497 FALSE 170.1 Bone cancer Both 48 806 2 neoplasms darkcyan 806, 48 202, 13 201, 14 201, 7 202, 14 -0.0104 0.151 0.945 0.02452 0.99 0.736 1.33 0.238 0.406 0.558 0.2535 1.27 0.572 2.81 -0.415 0.465 0.372 0.43 0.66 0.266 1.64 0.231 0.403 0.566 0.2475 1.26 0.573 2.77 PRS_PLINK_0.00398107170553497 TRUE 170.2 Cancer of connective tissue Both 85 1321 2 neoplasms darkcyan 1321, 85 331, 25 330, 20 330, 20 330, 20 -0.0579 0.118 0.623 0.2052 0.944 0.749 1.19 -0.241 0.302 0.424 0.3723 0.786 0.435 1.42 -0.125 0.309 0.685 0.1643 0.882 0.481 1.62 -0.254 0.312 0.415 0.3817 0.776 0.421 1.43 PRS_PLINK_0.00398107170553497 FALSE 172 Skin cancer Both 996 3559 2 neoplasms darkcyan 3559, 996 890, 245 890, 247 889, 244 890, 259 0.0126 0.0385 0.744 0.1283 1.01 0.939 1.09 -0.0265 0.106 0.803 0.09511 0.974 0.791 1.2 -0.0156 0.109 0.886 0.05256 0.985 0.795 1.22 0.0313 0.111 0.777 0.1094 1.03 0.831 1.28 PRS_PLINK_0.00398107170553497 FALSE 172.1 Melanomas of skin, dx or hx Both 677 3224 2 neoplasms darkcyan 3224, 677 806, 161 806, 165 806, 168 806, 182 0.0413 0.0448 0.357 0.4472 1.04 0.955 1.14 -0.0228 0.125 0.855 0.06784 0.977 0.765 1.25 0.00614 0.127 0.962 0.01702 1.01 0.784 1.29 0.0969 0.128 0.449 0.3481 1.1 0.857 1.42 PRS_PLINK_0.00398107170553497 FALSE 172.11 Melanomas of skin Both 236 2544 2 neoplasms darkcyan 2544, 236 636, 62 636, 59 636, 52 636, 63 0.0317 0.0702 0.651 0.1863 1.03 0.9 1.18 -0.0572 0.192 0.766 0.1156 0.944 0.648 1.38 -0.106 0.201 0.598 0.2232 0.899 0.607 1.33 0.0147 0.197 0.94 0.0267 1.01 0.69 1.49 PRS_PLINK_0.00398107170553497 FALSE 172.2 Other non-epithelial cancer of skin Both 886 3305 2 neoplasms darkcyan 3305, 886 827, 211 826, 219 826, 218 826, 237 0.0296 0.0405 0.464 0.3332 1.03 0.951 1.12 0.0111 0.113 0.921 0.03565 1.01 0.811 1.26 0.00842 0.115 0.942 0.02614 1.01 0.805 1.26 0.0774 0.117 0.507 0.2946 1.08 0.859 1.36 PRS_PLINK_0.00398107170553497 FALSE 172.21 Basal cell carcinoma Both 591 2644 2 neoplasms darkcyan 2644, 591 661, 136 661, 155 661, 139 661, 161 0.0258 0.0483 0.594 0.2265 1.03 0.933 1.13 0.0826 0.132 0.531 0.2747 1.09 0.839 1.41 0.0075 0.138 0.957 0.01931 1.01 0.769 1.32 0.117 0.136 0.391 0.4076 1.12 0.86 1.47 PRS_PLINK_0.00398107170553497 FALSE 172.22 Squamous cell carcinoma Both 271 1752 2 neoplasms darkcyan 1752, 271 438, 58 438, 70 438, 65 438, 78 0.1 0.0674 0.138 0.8616 1.11 0.969 1.26 0.16 0.191 0.402 0.3952 1.17 0.807 1.71 0.126 0.201 0.528 0.2771 1.13 0.766 1.68 0.316 0.194 0.103 0.9871 1.37 0.938 2.01 PRS_PLINK_0.00398107170553497 FALSE 172.3 Carcinoma in situ of skin Both 245 1316 2 neoplasms darkcyan 1316, 245 329, 69 329, 58 329, 55 329, 63 -0.0084 0.0716 0.907 0.04257 0.992 0.862 1.14 -0.199 0.195 0.307 0.5135 0.819 0.559 1.2 -0.197 0.2 0.325 0.488 0.821 0.555 1.22 -0.0599 0.197 0.761 0.1186 0.942 0.64 1.39 PRS_PLINK_0.00398107170553497 FALSE 173 Neoplasm of uncertain behavior of skin Both 439 2240 2 neoplasms darkcyan 2240, 439 560, 102 560, 102 560, 111 560, 124 0.07 0.0537 0.192 0.7161 1.07 0.965 1.19 -0.00711 0.154 0.963 0.01631 0.993 0.734 1.34 0.0662 0.152 0.663 0.1783 1.07 0.793 1.44 0.218 0.152 0.15 0.8235 1.24 0.924 1.67 PRS_PLINK_0.00398107170553497 FALSE 174 Breast cancer Both 665 2135 2 neoplasms darkcyan 2135, 665 533, 150 534, 174 533, 170 534, 171 0.0249 0.0465 0.592 0.2275 1.03 0.936 1.12 0.106 0.13 0.414 0.3827 1.11 0.862 1.43 0.0915 0.132 0.489 0.3108 1.1 0.846 1.42 0.0946 0.135 0.483 0.316 1.1 0.844 1.43 PRS_PLINK_0.00398107170553497 FALSE 174.1 Breast cancer [female] Female 639 2090 2 neoplasms darkcyan 2090, 639 522, 140 522, 175 522, 160 523, 164 0.0252 0.0474 0.595 0.2257 1.03 0.935 1.13 0.18 0.132 0.173 0.7622 1.2 0.924 1.55 0.088 0.136 0.519 0.2852 1.09 0.836 1.43 0.124 0.138 0.368 0.4337 1.13 0.864 1.49 PRS_PLINK_0.00398107170553497 FALSE 174.11 Malignant neoplasm of female breast Female 625 2074 2 neoplasms darkcyan 2074, 625 518, 137 518, 168 518, 159 519, 161 0.0318 0.0477 0.504 0.2972 1.03 0.94 1.13 0.16 0.134 0.232 0.6349 1.17 0.903 1.52 0.101 0.137 0.46 0.3376 1.11 0.846 1.45 0.128 0.14 0.358 0.4459 1.14 0.865 1.49 PRS_PLINK_0.00398107170553497 FALSE 174.3 Neoplasm of uncertain behavior of breast Both 73 328 2 neoplasms darkcyan 328, 73 82, 12 82, 24 82, 21 82, 16 0.00995 0.143 0.944 0.02487 1.01 0.764 1.34 0.566 0.405 0.162 0.7916 1.76 0.797 3.89 PRS_PLINK_0.00398107170553497 FALSE 175 Acquired absence of breast Female 196 918 2 neoplasms darkcyan 918, 196 230, 47 229, 51 229, 48 230, 50 0.041 0.0814 0.615 0.2111 1.04 0.888 1.22 0.0747 0.224 0.738 0.1318 1.08 0.695 1.67 0.0378 0.23 0.869 0.06075 1.04 0.661 1.63 0.0472 0.227 0.836 0.07797 1.05 0.671 1.64 PRS_PLINK_0.00398107170553497 FALSE 180 Cervical cancer and dysplasia Female 290 1511 2 neoplasms darkcyan 1511, 290 377, 63 378, 61 377, 81 378, 85 0.174 0.0642 0.00655 2.184 1.19 1.05 1.35 0.021 0.195 0.914 0.03911 1.02 0.697 1.5 0.309 0.187 0.0987 1.006 1.36 0.944 1.96 0.351 0.187 0.0603 1.219 1.42 0.985 2.05 PRS_PLINK_0.00398107170553497 FALSE 180.1 Cervical cancer Female 49 613 2 neoplasms darkcyan 613, 49 154, 13 153, 9 153, 9 153, 18 0.287 0.149 0.0545 1.264 1.33 0.994 1.78 -0.201 0.423 0.634 0.1978 0.818 0.357 1.87 -0.3 0.452 0.508 0.2945 0.741 0.305 1.8 0.528 0.385 0.171 0.7676 1.7 0.797 3.61 PRS_PLINK_0.00398107170553497 TRUE 180.3 Cervical intraepithelial neoplasia [CIN] [Cervical dysplasia] Female 262 1098 2 neoplasms darkcyan 1098, 262 274, 55 274, 58 274, 75 275, 74 0.175 0.0691 0.0115 1.939 1.19 1.04 1.36 0.116 0.208 0.578 0.2378 1.12 0.746 1.69 0.395 0.203 0.0514 1.289 1.48 0.998 2.21 0.356 0.206 0.0842 1.074 1.43 0.953 2.14 PRS_PLINK_0.00398107170553497 FALSE 182 Malignant neoplasm of uterus Female 91 1107 2 neoplasms darkcyan 1107, 91 276, 19 277, 26 276, 28 277, 18 0.00626 0.112 0.955 0.01982 1.01 0.808 1.25 0.371 0.31 0.231 0.637 1.45 0.79 2.66 0.267 0.317 0.4 0.3981 1.31 0.702 2.43 0.0779 0.347 0.822 0.08506 1.08 0.548 2.13 PRS_PLINK_0.00398107170553497 FALSE 184 Cancer of other female genital organs Female 196 1817 2 neoplasms darkcyan 1817, 196 454, 40 454, 43 454, 59 454, 54 0.149 0.0777 0.0548 1.262 1.16 0.997 1.35 0.0276 0.228 0.904 0.04394 1.03 0.657 1.61 0.376 0.217 0.0839 1.076 1.46 0.951 2.23 0.327 0.224 0.144 0.8418 1.39 0.894 2.15 PRS_PLINK_0.00398107170553497 FALSE 184.1 Malignant neoplasm of ovary and other uterine adnexa Female 95 927 2 neoplasms darkcyan 927, 95 232, 21 232, 26 231, 26 232, 22 0.0728 0.11 0.508 0.2945 1.08 0.867 1.33 0.245 0.308 0.426 0.3707 1.28 0.699 2.34 0.309 0.319 0.333 0.4779 1.36 0.729 2.55 0.0846 0.323 0.794 0.1003 1.09 0.577 2.05 PRS_PLINK_0.00398107170553497 FALSE 184.11 Malignant neoplasm of ovary Female 68 685 2 neoplasms darkcyan 685, 68 172, 14 171, 18 171, 21 171, 15 0.0257 0.127 0.839 0.07611 1.03 0.8 1.32 0.273 0.372 0.462 0.335 1.31 0.634 2.72 0.518 0.365 0.156 0.8062 1.68 0.82 3.44 0.0582 0.384 0.879 0.05583 1.06 0.5 2.25 PRS_PLINK_0.00398107170553497 FALSE 184.2 Cancer of other female genital organs (excluding uterus and ovary) Female 113 981 2 neoplasms darkcyan 981, 113 246, 23 245, 24 245, 34 245, 32 0.163 0.102 0.112 0.9525 1.18 0.963 1.44 0.0482 0.3 0.872 0.05924 1.05 0.582 1.89 0.484 0.288 0.0935 1.029 1.62 0.922 2.85 0.438 0.297 0.14 0.8543 1.55 0.866 2.77 PRS_PLINK_0.00398107170553497 FALSE 185 Cancer of prostate Male 149 464 2 neoplasms darkcyan 464, 149 116, 27 116, 37 116, 45 116, 40 0.131 0.108 0.225 0.6475 1.14 0.922 1.41 0.341 0.311 0.273 0.5634 1.41 0.764 2.59 0.651 0.317 0.0398 1.4 1.92 1.03 3.57 0.34 0.317 0.284 0.5464 1.4 0.754 2.61 PRS_PLINK_0.00398107170553497 FALSE 187 Cancer of other male genital organs Male 21 168 2 neoplasms darkcyan 168, 21 42, 7 42, 3 42, 5 42, 6 -0.0843 0.231 0.716 0.1453 0.919 0.584 1.45 -0.622 0.678 0.359 0.4455 0.537 0.142 2.03 -0.489 0.697 0.483 0.3165 0.613 0.157 2.4 -0.695 0.64 0.278 0.5564 0.499 0.142 1.75 PRS_PLINK_0.00398107170553497 TRUE 187.1 Malignant neoplasm of unspecified male genital organ Male 4 55 2 neoplasms darkcyan 55, 4 14, 0 14, 1 13, 2 14, 1 1.57 1.05 0.135 0.8691 4.83 0.612 38.1 0.656 1.4 0.639 0.1943 1.93 0.124 29.9 1.18 1.39 0.396 0.4024 3.26 0.213 49.9 1.2 1.46 0.413 0.384 3.32 0.188 58.5 PRS_PLINK_0.00398107170553497 TRUE 187.2 Malignant neoplasm of testis Male 14 90 2 neoplasms darkcyan 90, 14 23, 6 22, 3 22, 0 23, 5 -0.386 0.288 0.179 0.7463 0.68 0.387 1.19 -1.51 0.913 0.0978 1.01 0.221 0.0368 1.32 -3.56 1.62 0.0281 1.551 0.0285 0.00119 0.682 -0.725 0.777 0.351 0.4548 0.485 0.106 2.22 PRS_PLINK_0.00398107170553497 TRUE 187.8 Neoplasm of uncertain behavior of male genital organs Male 5 21 2 neoplasms darkcyan 21, 5 6, 2 5, 1 5, 1 5, 1 -0.469 0.55 0.394 0.4045 0.626 0.213 1.84 1.53 2.23 0.493 0.3075 4.62 0.0585 365 -0.291 1.88 0.877 0.05712 0.748 0.0189 29.5 -1.71 1.75 0.33 0.4815 0.182 0.00586 5.62 PRS_PLINK_0.00398107170553497 TRUE 189 Cancer of urinary organs (incl. kidney and bladder) Both 178 2359 2 neoplasms darkcyan 2359, 178 590, 50 590, 47 589, 43 590, 38 -0.0775 0.0802 0.334 0.4765 0.925 0.791 1.08 -0.0687 0.212 0.746 0.1275 0.934 0.616 1.41 -0.15 0.217 0.488 0.3114 0.86 0.563 1.32 -0.304 0.228 0.182 0.7403 0.738 0.472 1.15 PRS_PLINK_0.00398107170553497 FALSE 189.1 Cancer of kidney and renal pelvis Both 89 1453 2 neoplasms darkcyan 1453, 89 364, 25 363, 26 363, 21 363, 17 -0.122 0.11 0.268 0.5713 0.885 0.713 1.1 0.0505 0.288 0.861 0.06512 1.05 0.598 1.85 -0.136 0.303 0.654 0.1844 0.873 0.482 1.58 -0.354 0.321 0.27 0.5679 0.702 0.374 1.32 PRS_PLINK_0.00398107170553497 FALSE 189.11 Malignant neoplasm of kidney, except pelvis Both 74 1220 2 neoplasms darkcyan 1220, 74 305, 22 305, 24 305, 15 305, 13 -0.114 0.12 0.344 0.4636 0.892 0.705 1.13 0.204 0.307 0.507 0.2954 1.23 0.672 2.24 -0.278 0.339 0.412 0.3853 0.757 0.39 1.47 -0.441 0.355 0.213 0.6707 0.643 0.321 1.29 PRS_PLINK_0.00398107170553497 FALSE 189.12 Malignant neoplasm of renal pelvis Both 16 218 2 neoplasms darkcyan 218, 16 55, 4 54, 8 54, 1 55, 3 -0.122 0.233 0.601 0.2211 0.885 0.56 1.4 0.921 0.696 0.185 0.7322 2.51 0.643 9.82 -0.847 0.833 0.309 0.5094 0.429 0.0838 2.19 0.445 0.806 0.581 0.2359 1.56 0.322 7.57 PRS_PLINK_0.00398107170553497 TRUE 189.2 Cancer of bladder Both 103 1380 2 neoplasms darkcyan 1380, 103 345, 23 345, 30 345, 26 345, 24 0.00673 0.106 0.949 0.02259 1.01 0.818 1.24 0.224 0.29 0.439 0.3572 1.25 0.709 2.21 0.107 0.292 0.715 0.1455 1.11 0.628 1.97 0.0443 0.309 0.886 0.05262 1.05 0.571 1.91 PRS_PLINK_0.00398107170553497 FALSE 189.21 Malignant neoplasm of bladder Both 84 1238 2 neoplasms darkcyan 1238, 84 310, 19 309, 23 309, 23 310, 19 0.00764 0.116 0.948 0.02337 1.01 0.802 1.27 0.165 0.323 0.61 0.2148 1.18 0.626 2.22 0.136 0.314 0.664 0.1779 1.15 0.62 2.12 -0.0848 0.341 0.803 0.09502 0.919 0.471 1.79 PRS_PLINK_0.00398107170553497 FALSE 189.4 Malignant neoplasm of other urinary organs Both 25 539 2 neoplasms darkcyan 539, 25 135, 7 135, 8 134, 8 135, 2 -0.138 0.197 0.484 0.3155 0.871 0.593 1.28 0.217 0.498 0.662 0.1789 1.24 0.468 3.3 0.203 0.496 0.683 0.1656 1.22 0.463 3.24 -0.902 0.691 0.192 0.7171 0.406 0.105 1.57 PRS_PLINK_0.00398107170553497 TRUE 190 Cancer of eye Both 14 153 2 neoplasms darkcyan 153, 14 39, 4 38, 1 38, 6 38, 3 -0.0562 0.307 0.855 0.06802 0.945 0.518 1.73 -0.84 0.889 0.345 0.4624 0.432 0.0756 2.47 0.0362 0.7 0.959 0.01828 1.04 0.263 4.09 -0.558 0.774 0.471 0.3271 0.572 0.126 2.61 PRS_PLINK_0.00398107170553497 TRUE 191 Manlignant and unknown neoplasms of brain and nervous system Both 86 1069 2 neoplasms darkcyan 1069, 86 268, 20 267, 20 267, 25 267, 21 -0.0177 0.115 0.878 0.05653 0.982 0.784 1.23 -0.0156 0.32 0.961 0.01723 0.985 0.526 1.84 0.224 0.306 0.464 0.3338 1.25 0.687 2.28 0.0715 0.325 0.826 0.08316 1.07 0.568 2.03 PRS_PLINK_0.00398107170553497 FALSE 191.1 Cancer of brain and nervous system Both 50 676 2 neoplasms darkcyan 676, 50 169, 12 169, 13 169, 17 169, 8 -0.152 0.152 0.319 0.4957 0.859 0.637 1.16 0.0482 0.399 0.904 0.04392 1.05 0.48 2.29 0.358 0.384 0.351 0.455 1.43 0.674 3.03 -0.426 0.446 0.339 0.4699 0.653 0.272 1.56 PRS_PLINK_0.00398107170553497 TRUE 191.11 Cancer of brain Both 41 563 2 neoplasms darkcyan 563, 41 141, 9 141, 10 140, 13 141, 9 -0.0449 0.168 0.79 0.1025 0.956 0.687 1.33 0.0931 0.44 0.832 0.07973 1.1 0.464 2.6 0.332 0.419 0.429 0.3676 1.39 0.612 3.17 -0.116 0.455 0.798 0.09783 0.89 0.365 2.17 PRS_PLINK_0.00398107170553497 TRUE 193 Thyroid cancer Both 89 1149 2 neoplasms darkcyan 1149, 89 288, 17 287, 25 287, 28 287, 19 -0.0219 0.111 0.843 0.0742 0.978 0.787 1.22 0.433 0.323 0.18 0.7443 1.54 0.818 2.91 0.436 0.322 0.176 0.7551 1.55 0.823 2.91 0.06 0.344 0.861 0.06477 1.06 0.541 2.08 PRS_PLINK_0.00398107170553497 FALSE 194 Cancer of other endocrine glands Both 77 721 2 neoplasms darkcyan 721, 77 181, 26 180, 17 180, 24 180, 10 -0.271 0.125 0.0297 1.528 0.762 0.597 0.974 -0.478 0.327 0.143 0.8445 0.62 0.327 1.18 -0.0539 0.312 0.863 0.06398 0.948 0.514 1.75 -1.03 0.388 0.00777 2.11 0.356 0.166 0.761 PRS_PLINK_0.00398107170553497 FALSE 195 Cancer, suspected or other Both 1881 2782 2 neoplasms darkcyan 2782, 1881 696, 468 695, 469 695, 490 696, 453 -0.016 0.0329 0.626 0.2035 0.984 0.923 1.05 -0.0341 0.0901 0.705 0.1516 0.967 0.81 1.15 0.0151 0.0914 0.869 0.06085 1.02 0.849 1.21 -0.0752 0.0944 0.426 0.3711 0.928 0.771 1.12 PRS_PLINK_0.00398107170553497 FALSE 195.1 Malignant neoplasm, other Both 1860 2782 2 neoplasms darkcyan 2782, 1860 696, 461 695, 463 695, 485 696, 450 -0.0128 0.033 0.698 0.1563 0.987 0.925 1.05 -0.0353 0.0906 0.697 0.1569 0.965 0.808 1.15 0.0228 0.0917 0.804 0.09476 1.02 0.855 1.22 -0.0628 0.0947 0.507 0.2949 0.939 0.78 1.13 PRS_PLINK_0.00398107170553497 FALSE 195.3 Malignant neoplasm of head, face, and neck Both 75 846 2 neoplasms darkcyan 846, 75 212, 17 211, 15 211, 21 212, 22 0.106 0.118 0.372 0.429 1.11 0.881 1.4 -0.0824 0.358 0.818 0.08712 0.921 0.456 1.86 0.253 0.351 0.471 0.3267 1.29 0.647 2.56 0.404 0.354 0.255 0.5943 1.5 0.748 3 PRS_PLINK_0.00398107170553497 FALSE 196 Radiotherapy Both 369 1922 2 neoplasms darkcyan 1922, 369 481, 89 480, 89 480, 93 481, 98 0.0417 0.0596 0.484 0.3152 1.04 0.928 1.17 -0.00864 0.166 0.959 0.01838 0.991 0.716 1.37 0.0241 0.168 0.885 0.05282 1.02 0.738 1.42 0.145 0.17 0.392 0.4072 1.16 0.829 1.61 PRS_PLINK_0.00398107170553497 FALSE 197 Chemotherapy Both 545 2469 2 neoplasms darkcyan 2469, 545 618, 138 617, 138 617, 131 617, 137 -0.00596 0.0492 0.904 0.04402 0.994 0.903 1.09 0.0123 0.136 0.928 0.03256 1.01 0.775 1.32 -0.0246 0.14 0.86 0.0653 0.976 0.741 1.28 0.00791 0.142 0.955 0.01978 1.01 0.764 1.33 PRS_PLINK_0.00398107170553497 FALSE 198 Secondary malignant neoplasm Both 441 2434 2 neoplasms darkcyan 2434, 441 609, 106 608, 126 608, 110 609, 98 -0.0743 0.0546 0.173 0.7612 0.928 0.834 1.03 0.153 0.146 0.296 0.5285 1.17 0.875 1.55 -0.00171 0.154 0.991 0.003875 0.998 0.739 1.35 -0.13 0.16 0.415 0.3825 0.878 0.642 1.2 PRS_PLINK_0.00398107170553497 FALSE 198.1 Secondary malignancy of lymph nodes Both 282 2245 2 neoplasms darkcyan 2245, 282 562, 69 561, 78 561, 70 561, 65 -0.0641 0.0657 0.329 0.4829 0.938 0.825 1.07 0.144 0.177 0.415 0.382 1.16 0.817 1.63 -0.0124 0.185 0.946 0.02396 0.988 0.687 1.42 -0.0709 0.191 0.711 0.1482 0.932 0.64 1.36 PRS_PLINK_0.00398107170553497 FALSE 198.2 Secondary malignancy of respiratory organs Both 80 980 2 neoplasms darkcyan 980, 80 245, 21 245, 23 245, 25 245, 11 -0.199 0.118 0.0907 1.042 0.82 0.651 1.03 0.125 0.307 0.684 0.1652 1.13 0.621 2.07 0.162 0.306 0.597 0.2239 1.18 0.645 2.14 -0.691 0.373 0.0642 1.192 0.501 0.241 1.04 PRS_PLINK_0.00398107170553497 FALSE 198.3 Secondary malignant neoplasm of digestive systems Both 78 950 2 neoplasms darkcyan 950, 78 238, 22 237, 21 237, 20 238, 15 -0.141 0.121 0.246 0.6097 0.869 0.685 1.1 -0.0519 0.313 0.868 0.06136 0.949 0.514 1.75 -0.0528 0.316 0.867 0.06186 0.949 0.511 1.76 -0.404 0.348 0.245 0.6103 0.667 0.337 1.32 PRS_PLINK_0.00398107170553497 FALSE 198.4 Secondary malignant neoplasm of liver Both 67 751 2 neoplasms darkcyan 751, 67 188, 22 188, 14 187, 19 188, 12 -0.163 0.129 0.208 0.6827 0.85 0.66 1.09 -0.377 0.349 0.28 0.5527 0.686 0.346 1.36 -0.149 0.328 0.649 0.1878 0.861 0.453 1.64 -0.712 0.374 0.0569 1.245 0.49 0.236 1.02 PRS_PLINK_0.00398107170553497 FALSE 198.5 Secondary malignancy of brain/spine Both 35 628 2 neoplasms darkcyan 628, 35 157, 11 157, 12 157, 8 157, 3 -0.469 0.17 0.00577 2.239 0.626 0.449 0.873 0.1 0.409 0.807 0.09332 1.11 0.496 2.47 -0.271 0.447 0.544 0.2643 0.763 0.318 1.83 -1.25 0.584 0.0319 1.497 0.285 0.0908 0.897 PRS_PLINK_0.00398107170553497 TRUE 198.6 Secondary malignancy of bone Both 60 801 2 neoplasms darkcyan 801, 60 201, 16 200, 17 200, 18 200, 8 -0.232 0.138 0.0929 1.032 0.793 0.605 1.04 0.0161 0.358 0.964 0.0159 1.02 0.504 2.05 0.172 0.355 0.628 0.2022 1.19 0.592 2.38 -0.792 0.436 0.0691 1.16 0.453 0.193 1.06 PRS_PLINK_0.00398107170553497 FALSE 198.7 Secondary malignant neoplasm of skin Both 24 331 2 neoplasms darkcyan 331, 24 83, 6 83, 7 82, 6 83, 5 -0.194 0.218 0.374 0.4274 0.824 0.538 1.26 0.0336 0.534 0.95 0.02235 1.03 0.363 2.94 -0.13 0.569 0.82 0.08623 0.879 0.288 2.68 -0.286 0.603 0.635 0.1975 0.751 0.231 2.45 PRS_PLINK_0.00398107170553497 TRUE 199 Neoplasm of uncertain behavior Both 771 2735 2 neoplasms darkcyan 2735, 771 684, 180 684, 189 683, 221 684, 181 0.0163 0.0439 0.71 0.1485 1.02 0.933 1.11 0.0331 0.121 0.785 0.1051 1.03 0.815 1.31 0.197 0.121 0.104 0.9845 1.22 0.961 1.54 0.0146 0.127 0.909 0.04167 1.01 0.791 1.3 PRS_PLINK_0.00398107170553497 FALSE 199.4 Neurofibromatosis Both 10 94 2 neoplasms darkcyan 94, 10 24, 3 23, 2 23, 4 24, 1 -0.51 0.348 0.143 0.8432 0.601 0.303 1.19 -0.336 1.05 0.749 0.1255 0.715 0.0915 5.59 -0.107 0.765 0.889 0.05093 0.899 0.201 4.03 -1.2 1.06 0.256 0.5923 0.301 0.0379 2.39 PRS_PLINK_0.00398107170553497 TRUE 200 Myeloproliferative disease Both 148 1167 2 neoplasms darkcyan 1167, 148 292, 32 292, 44 291, 40 292, 32 -0.0493 0.0893 0.581 0.2358 0.952 0.799 1.13 0.301 0.245 0.219 0.6589 1.35 0.836 2.19 0.18 0.253 0.477 0.3212 1.2 0.729 1.97 0.104 0.267 0.696 0.1575 1.11 0.658 1.87 PRS_PLINK_0.00398107170553497 FALSE 200.1 Polycythemia vera Both 29 192 2 neoplasms darkcyan 192, 29 48, 6 48, 9 48, 7 48, 7 0.0133 0.225 0.953 0.02089 1.01 0.652 1.57 0.246 0.531 0.643 0.1915 1.28 0.452 3.62 0.00958 0.592 0.987 0.005644 1.01 0.317 3.22 0.137 0.596 0.818 0.08733 1.15 0.356 3.69 PRS_PLINK_0.00398107170553497 TRUE 201 Hodgkin's disease Both 23 174 2 neoplasms darkcyan 174, 23 44, 5 43, 5 43, 8 44, 5 -0.0469 0.226 0.836 0.07803 0.954 0.613 1.49 0.0155 0.658 0.981 0.008213 1.02 0.28 3.69 0.516 0.595 0.386 0.4135 1.68 0.522 5.38 -0.241 0.711 0.734 0.1342 0.785 0.195 3.16 PRS_PLINK_0.00398107170553497 TRUE 202 Cancer of other lymphoid, histiocytic tissue Both 187 1687 2 neoplasms darkcyan 1687, 187 422, 47 422, 51 421, 46 422, 43 -0.0423 0.0794 0.594 0.2259 0.959 0.82 1.12 0.0816 0.212 0.7 0.1549 1.08 0.717 1.64 -0.0151 0.22 0.945 0.02447 0.985 0.64 1.52 0.0137 0.227 0.952 0.02145 1.01 0.65 1.58 PRS_PLINK_0.00398107170553497 FALSE 202.2 Non-Hodgkins lymphoma Both 163 1447 2 neoplasms darkcyan 1447, 163 362, 39 362, 45 361, 43 362, 36 -0.0198 0.0855 0.817 0.08787 0.98 0.829 1.16 0.159 0.229 0.489 0.3111 1.17 0.748 1.84 0.102 0.234 0.662 0.1794 1.11 0.701 1.75 0.0451 0.249 0.857 0.06725 1.05 0.642 1.71 PRS_PLINK_0.00398107170553497 FALSE 202.21 Nodular lymphoma Both 111 847 2 neoplasms darkcyan 847, 111 212, 25 212, 32 211, 34 212, 20 -0.0246 0.104 0.814 0.0893 0.976 0.795 1.2 0.232 0.28 0.406 0.391 1.26 0.729 2.18 0.279 0.284 0.326 0.4869 1.32 0.757 2.31 -0.169 0.317 0.594 0.2261 0.845 0.454 1.57 PRS_PLINK_0.00398107170553497 FALSE 202.22 Reticulosarcoma Both 11 151 2 neoplasms darkcyan 151, 11 38, 2 38, 1 37, 4 38, 4 0.134 0.292 0.647 0.1893 1.14 0.645 2.03 -0.435 0.91 0.632 0.199 0.647 0.109 3.85 0.182 0.878 0.836 0.07779 1.2 0.214 6.71 0.143 0.881 0.871 0.05997 1.15 0.205 6.49 PRS_PLINK_0.00398107170553497 TRUE 202.24 Large cell lymphoma Both 11 123 2 neoplasms darkcyan 123, 11 31, 2 31, 1 30, 4 31, 4 0.34 0.329 0.302 0.5203 1.41 0.737 2.68 -0.343 0.906 0.705 0.152 0.709 0.12 4.19 -0.00697 0.829 0.993 0.002922 0.993 0.196 5.04 0.51 0.912 0.576 0.2397 1.67 0.279 9.95 PRS_PLINK_0.00398107170553497 TRUE 204 Leukemia Both 85 687 2 neoplasms darkcyan 687, 85 172, 20 172, 25 171, 20 172, 20 0.0431 0.115 0.707 0.1507 1.04 0.834 1.31 0.238 0.318 0.454 0.3434 1.27 0.681 2.36 0.0456 0.331 0.891 0.05033 1.05 0.547 2 0.183 0.343 0.594 0.2261 1.2 0.613 2.35 PRS_PLINK_0.00398107170553497 FALSE 204.1 Lymphoid leukemia Both 25 233 2 neoplasms darkcyan 233, 25 59, 7 58, 6 58, 8 58, 4 -0.0888 0.211 0.674 0.1712 0.915 0.605 1.38 -0.156 0.551 0.777 0.1095 0.856 0.291 2.52 -0.0141 0.541 0.979 0.009132 0.986 0.342 2.84 -0.142 0.639 0.824 0.08431 0.867 0.248 3.03 PRS_PLINK_0.00398107170553497 TRUE 204.11 Lymphoid leukemia, acute Both 10 45 2 neoplasms darkcyan 45, 10 12, 1 11, 5 11, 1 11, 3 -0.181 0.401 0.653 0.1853 0.835 0.38 1.83 0.435 1.1 0.692 0.1597 1.55 0.179 13.4 -1.97 1.87 0.292 0.5347 0.139 0.00356 5.45 1.01 1.25 0.418 0.3786 2.75 0.237 32 PRS_PLINK_0.00398107170553497 TRUE 204.12 Lymphoid leukemia, chronic Both 17 180 2 neoplasms darkcyan 180, 17 45, 6 45, 5 45, 3 45, 3 -0.226 0.248 0.363 0.4396 0.798 0.49 1.3 0.0535 0.599 0.929 0.03205 1.05 0.326 3.42 -0.572 0.694 0.41 0.3873 0.565 0.145 2.2 0.0224 0.728 0.975 0.01081 1.02 0.245 4.26 PRS_PLINK_0.00398107170553497 TRUE 204.2 Myeloid leukemia Both 34 271 2 neoplasms darkcyan 271, 34 68, 6 68, 10 67, 7 68, 11 0.268 0.183 0.145 0.8401 1.31 0.912 1.87 0.39 0.528 0.46 0.3371 1.48 0.524 4.16 0.334 0.577 0.563 0.2495 1.4 0.45 4.33 0.636 0.507 0.209 0.6793 1.89 0.7 5.1 PRS_PLINK_0.00398107170553497 TRUE 204.21 Myeloid leukemia, acute Both 20 157 2 neoplasms darkcyan 157, 20 40, 4 39, 2 39, 5 39, 9 0.462 0.233 0.0471 1.327 1.59 1.01 2.5 -0.678 0.838 0.418 0.3783 0.508 0.0983 2.62 0.848 0.759 0.264 0.5786 2.34 0.527 10.3 1.26 0.678 0.0634 1.198 3.52 0.932 13.3 PRS_PLINK_0.00398107170553497 TRUE 204.22 Myeloid leukemia, chronic Both 11 63 2 neoplasms darkcyan 63, 11 16, 1 16, 3 15, 3 16, 4 0.731 0.416 0.0789 1.103 2.08 0.919 4.7 0.515 1.02 0.614 0.2118 1.67 0.226 12.4 0.453 1.11 0.682 0.1662 1.57 0.18 13.8 1.4 1.04 0.178 0.7491 4.04 0.53 30.7 PRS_PLINK_0.00398107170553497 TRUE 204.4 Multiple myeloma Both 23 234 2 neoplasms darkcyan 234, 23 59, 6 58, 8 58, 5 59, 4 -0.109 0.216 0.614 0.2118 0.897 0.587 1.37 0.402 0.567 0.478 0.3203 1.49 0.492 4.54 -0.0149 0.614 0.981 0.008521 0.985 0.296 3.28 0.0339 0.677 0.96 0.01772 1.03 0.275 3.9 PRS_PLINK_0.00398107170553497 TRUE 208 Benign neoplasm of colon Both 2087 2965 2 neoplasms darkcyan 2965, 2087 741, 470 741, 526 741, 531 741, 560 0.0548 0.0309 0.0762 1.118 1.06 0.994 1.12 0.0768 0.0864 0.374 0.4269 1.08 0.912 1.28 0.0918 0.088 0.297 0.5276 1.1 0.923 1.3 0.158 0.0891 0.0758 1.12 1.17 0.984 1.4 PRS_PLINK_0.00398107170553497 FALSE 209 Neuroendocrine tumors Both 25 294 2 neoplasms darkcyan 294, 25 74, 7 73, 5 73, 4 74, 9 -0.129 0.211 0.542 0.266 0.879 0.581 1.33 -0.404 0.566 0.475 0.3235 0.667 0.22 2.02 -0.397 0.613 0.517 0.2869 0.672 0.202 2.23 0.102 0.525 0.846 0.07265 1.11 0.396 3.1 PRS_PLINK_0.00398107170553497 TRUE 210 Benign neoplasm of lip, oral cavity, and pharynx Both 163 1824 2 neoplasms darkcyan 1824, 163 455, 40 456, 52 456, 34 456, 37 -0.0122 0.082 0.881 0.05484 0.988 0.841 1.16 0.369 0.226 0.103 0.9884 1.45 0.928 2.25 -0.0875 0.247 0.723 0.1411 0.916 0.565 1.49 0.0815 0.246 0.74 0.1306 1.08 0.67 1.76 PRS_PLINK_0.00398107170553497 FALSE 211 Benign neoplasm of other parts of digestive system Both 1222 3724 2 neoplasms darkcyan 3724, 1222 930, 302 931, 303 931, 307 931, 310 0.0188 0.034 0.581 0.2356 1.02 0.953 1.09 -0.00351 0.0952 0.971 0.01296 0.996 0.827 1.2 0.0133 0.0962 0.89 0.05043 1.01 0.839 1.22 0.0193 0.0973 0.843 0.07419 1.02 0.842 1.23 PRS_PLINK_0.00398107170553497 FALSE 212 Benign neoplasm of respiratory and intrathoracic organs Both 176 1792 2 neoplasms darkcyan 1792, 176 447, 61 448, 47 448, 34 448, 34 -0.272 0.0807 0.000737 3.132 0.762 0.65 0.892 -0.263 0.205 0.2 0.698 0.769 0.514 1.15 -0.606 0.228 0.00782 2.107 0.546 0.349 0.853 -0.621 0.23 0.00697 2.157 0.537 0.342 0.844 PRS_PLINK_0.00398107170553497 FALSE 213 Benign neoplasm of bone and articular cartilage Both 158 1017 2 neoplasms darkcyan 1017, 158 255, 41 254, 45 254, 35 254, 36 -0.0692 0.0882 0.433 0.3634 0.933 0.785 1.11 0.136 0.235 0.562 0.2502 1.15 0.723 1.82 -0.11 0.25 0.661 0.1801 0.896 0.549 1.46 0.118 0.257 0.647 0.1893 1.13 0.68 1.86 PRS_PLINK_0.00398107170553497 FALSE 214 Lipoma Both 277 1687 2 neoplasms darkcyan 1687, 277 421, 69 422, 74 421, 80 422, 54 -0.0638 0.0676 0.345 0.4618 0.938 0.822 1.07 0.0373 0.181 0.837 0.07721 1.04 0.727 1.48 0.13 0.181 0.472 0.326 1.14 0.799 1.62 -0.258 0.201 0.2 0.6987 0.773 0.521 1.15 PRS_PLINK_0.00398107170553497 FALSE 214.1 Lipoma of skin and subcutaneous tissue Both 176 1037 2 neoplasms darkcyan 1037, 176 259, 47 259, 46 259, 52 259, 31 -0.108 0.085 0.206 0.6871 0.898 0.76 1.06 -0.0816 0.225 0.717 0.1444 0.922 0.593 1.43 0.122 0.223 0.584 0.2335 1.13 0.73 1.75 -0.418 0.25 0.0948 1.023 0.658 0.403 1.08 PRS_PLINK_0.00398107170553497 FALSE 215 Other benign neoplasm of connective and other soft tissue Both 641 4149 2 neoplasms darkcyan 4149, 641 1037, 169 1037, 164 1037, 174 1037, 134 -0.0758 0.0438 0.0839 1.076 0.927 0.851 1.01 -0.0482 0.119 0.686 0.1637 0.953 0.755 1.2 0.0023 0.119 0.985 0.006738 1 0.794 1.27 -0.254 0.128 0.0465 1.333 0.776 0.604 0.996 PRS_PLINK_0.00398107170553497 FALSE 216 Benign neoplasm of skin Both 2276 2882 2 neoplasms darkcyan 2882, 2276 721, 610 720, 575 720, 511 721, 579 -0.0172 0.0292 0.555 0.256 0.983 0.928 1.04 -0.0589 0.0804 0.464 0.3336 0.943 0.805 1.1 -0.154 0.0826 0.062 1.207 0.857 0.729 1.01 -0.0159 0.0827 0.848 0.07182 0.984 0.837 1.16 PRS_PLINK_0.00398107170553497 FALSE 216.1 Screening for malignant neoplasms of the skin Both 53 190 2 neoplasms darkcyan 190, 53 48, 15 47, 10 47, 10 48, 18 0.0487 0.167 0.77 0.1135 1.05 0.757 1.46 -0.387 0.468 0.408 0.3889 0.679 0.272 1.7 -0.307 0.467 0.51 0.2925 0.735 0.295 1.83 0.295 0.429 0.493 0.3076 1.34 0.579 3.11 PRS_PLINK_0.00398107170553497 FALSE 217 Vascular hamartomas and non-neoplastic nevi Both 516 1726 2 neoplasms darkcyan 1726, 516 432, 131 431, 113 431, 121 432, 151 0.0657 0.0512 0.199 0.7004 1.07 0.966 1.18 -0.137 0.147 0.351 0.4548 0.872 0.653 1.16 -0.098 0.147 0.505 0.297 0.907 0.68 1.21 0.184 0.143 0.198 0.7038 1.2 0.908 1.59 PRS_PLINK_0.00398107170553497 FALSE 217.1 Nevus, non-neoplastic Both 500 1652 2 neoplasms darkcyan 1652, 500 413, 126 413, 109 413, 116 413, 149 0.0673 0.0521 0.196 0.707 1.07 0.966 1.18 -0.122 0.15 0.416 0.3807 0.885 0.66 1.19 -0.0932 0.15 0.533 0.273 0.911 0.679 1.22 0.249 0.145 0.0872 1.06 1.28 0.964 1.7 PRS_PLINK_0.00398107170553497 FALSE 218 Benign neoplasm of uterus Female 1117 2301 2 neoplasms darkcyan 2301, 1117 575, 227 575, 268 575, 308 575, 314 0.114 0.0383 0.0028 2.553 1.12 1.04 1.21 0.164 0.11 0.137 0.8627 1.18 0.949 1.46 0.286 0.108 0.0082 2.086 1.33 1.08 1.64 0.308 0.11 0.00509 2.293 1.36 1.1 1.69 PRS_PLINK_0.00398107170553497 FALSE 218.1 Uterine leiomyoma Female 485 2180 2 neoplasms darkcyan 2180, 485 544, 103 545, 110 545, 126 545, 146 0.105 0.0519 0.0441 1.355 1.11 1 1.23 0.0571 0.151 0.706 0.1514 1.06 0.787 1.42 0.164 0.148 0.269 0.5707 1.18 0.881 1.58 0.287 0.148 0.0523 1.281 1.33 0.997 1.78 PRS_PLINK_0.00398107170553497 FALSE 218.2 Other benign neoplasm of uterus Female 875 2237 2 neoplasms darkcyan 2237, 875 559, 179 559, 204 559, 242 559, 250 0.124 0.0417 0.00287 2.543 1.13 1.04 1.23 0.118 0.121 0.329 0.4826 1.13 0.888 1.43 0.276 0.118 0.0193 1.715 1.32 1.05 1.66 0.326 0.12 0.00646 2.19 1.39 1.1 1.75 PRS_PLINK_0.00398107170553497 FALSE 220 Benign neoplasm of ovary Female 170 1041 2 neoplasms darkcyan 1041, 170 260, 37 260, 39 260, 42 260, 52 0.0958 0.0825 0.245 0.6106 1.1 0.936 1.29 0.0224 0.245 0.927 0.03276 1.02 0.632 1.65 0.106 0.242 0.662 0.1791 1.11 0.692 1.79 0.413 0.24 0.0849 1.071 1.51 0.945 2.42 PRS_PLINK_0.00398107170553497 FALSE 221 Benign neoplasm of other female genital organs Female 368 1805 2 neoplasms darkcyan 1805, 368 451, 78 451, 77 451, 97 451, 116 0.136 0.0584 0.0201 1.696 1.15 1.02 1.28 0.0074 0.176 0.966 0.01485 1.01 0.714 1.42 0.203 0.168 0.227 0.644 1.23 0.881 1.7 0.442 0.167 0.00812 2.091 1.56 1.12 2.16 PRS_PLINK_0.00398107170553497 FALSE 222 Benign neoplasm of male genital organs Male 74 570 2 neoplasms darkcyan 570, 74 143, 12 142, 16 142, 17 143, 29 0.271 0.132 0.041 1.387 1.31 1.01 1.7 0.122 0.397 0.758 0.1204 1.13 0.519 2.46 0.0758 0.392 0.847 0.07227 1.08 0.5 2.33 0.667 0.363 0.0661 1.18 1.95 0.957 3.97 PRS_PLINK_0.00398107170553497 FALSE 223 Benign neoplasm of kidney and other urinary organs Both 122 815 2 neoplasms darkcyan 815, 122 204, 30 204, 36 203, 18 204, 38 0.0538 0.101 0.595 0.2254 1.06 0.865 1.29 0.19 0.269 0.481 0.3183 1.21 0.713 2.05 -0.57 0.315 0.0699 1.156 0.565 0.305 1.05 0.247 0.266 0.353 0.4525 1.28 0.76 2.16 PRS_PLINK_0.00398107170553497 FALSE 224 Benign neoplasm of eye Both 150 837 2 neoplasms darkcyan 837, 150 210, 36 209, 40 209, 40 209, 34 -0.0707 0.0934 0.449 0.3476 0.932 0.776 1.12 0.0638 0.256 0.803 0.09519 1.07 0.645 1.76 0.113 0.252 0.653 0.1852 1.12 0.683 1.84 -0.0917 0.271 0.735 0.1338 0.912 0.537 1.55 PRS_PLINK_0.00398107170553497 FALSE 224.1 Benign neoplasm of eye, uveal Both 137 693 2 neoplasms darkcyan 693, 137 174, 35 173, 34 173, 35 173, 33 -0.0849 0.102 0.405 0.3921 0.919 0.752 1.12 -0.0831 0.271 0.759 0.1198 0.92 0.541 1.56 0.0271 0.267 0.919 0.03658 1.03 0.609 1.73 -0.0614 0.277 0.824 0.0839 0.94 0.547 1.62 PRS_PLINK_0.00398107170553497 FALSE 225 Benign neoplasm of brain and other parts of nervous system Both 124 1344 2 neoplasms darkcyan 1344, 124 335, 27 336, 36 336, 36 336, 25 0.0101 0.096 0.917 0.03783 1.01 0.837 1.22 0.319 0.263 0.225 0.6483 1.38 0.822 2.3 0.424 0.266 0.111 0.9528 1.53 0.907 2.58 0.0821 0.296 0.781 0.1072 1.09 0.608 1.94 PRS_PLINK_0.00398107170553497 FALSE 225.1 Benign neoplasm of brain, cranial nerves, meninges Both 94 1075 2 neoplasms darkcyan 1075, 94 268, 22 269, 26 268, 24 269, 22 0.0322 0.109 0.769 0.1143 1.03 0.833 1.28 0.129 0.299 0.666 0.1762 1.14 0.633 2.04 0.306 0.31 0.324 0.4893 1.36 0.739 2.5 0.148 0.325 0.649 0.1879 1.16 0.613 2.19 PRS_PLINK_0.00398107170553497 FALSE 225.2 Benign neoplasm of spinal cord, meninges Both 36 329 2 neoplasms darkcyan 329, 36 83, 13 82, 9 82, 9 82, 5 -0.323 0.186 0.0815 1.089 0.724 0.503 1.04 -0.299 0.461 0.517 0.2864 0.742 0.301 1.83 -0.324 0.453 0.475 0.3236 0.723 0.298 1.76 -0.711 0.52 0.172 0.7653 0.491 0.177 1.36 PRS_PLINK_0.00398107170553497 TRUE 226 Benign neoplasm of thyroid glands Both 208 1825 2 neoplasms darkcyan 1825, 208 456, 55 456, 65 456, 39 456, 49 -0.0482 0.0738 0.514 0.2888 0.953 0.825 1.1 0.165 0.195 0.397 0.4015 1.18 0.805 1.73 -0.375 0.22 0.0881 1.055 0.687 0.447 1.06 -0.0603 0.212 0.776 0.11 0.941 0.621 1.43 PRS_PLINK_0.00398107170553497 FALSE 227 Benign neoplasm of other endocrine glands and related structures Both 171 2053 2 neoplasms darkcyan 2053, 171 513, 43 513, 40 513, 43 513, 45 0.0628 0.0817 0.442 0.3542 1.06 0.907 1.25 -0.0208 0.227 0.927 0.03287 0.979 0.628 1.53 -0.00826 0.225 0.971 0.0129 0.992 0.638 1.54 0.127 0.228 0.576 0.2395 1.14 0.727 1.78 PRS_PLINK_0.00398107170553497 FALSE 227.1 Benign neoplasm of adrenal gland Both 51 560 2 neoplasms darkcyan 560, 51 140, 16 140, 9 140, 16 140, 10 -0.0709 0.148 0.632 0.199 0.932 0.697 1.25 -0.615 0.416 0.14 0.8544 0.541 0.239 1.22 -0.0537 0.368 0.884 0.05362 0.948 0.461 1.95 -0.47 0.408 0.25 0.6029 0.625 0.281 1.39 PRS_PLINK_0.00398107170553497 FALSE 227.2 Benign neoplasm of parathyroid gland Both 92 1025 2 neoplasms darkcyan 1025, 92 256, 22 256, 29 256, 16 256, 25 0.0291 0.111 0.793 0.101 1.03 0.829 1.28 0.381 0.297 0.2 0.6991 1.46 0.818 2.62 -0.226 0.334 0.498 0.3031 0.797 0.415 1.53 0.146 0.31 0.639 0.1944 1.16 0.629 2.13 PRS_PLINK_0.00398107170553497 FALSE 227.3 Benign neoplasm of pituitary gland and craniopharyngeal duct (pouch) Both 25 498 2 neoplasms darkcyan 498, 25 125, 3 124, 5 124, 8 125, 9 0.549 0.205 0.00737 2.133 1.73 1.16 2.59 0.541 0.618 0.381 0.4187 1.72 0.511 5.77 1.29 0.648 0.0468 1.329 3.63 1.02 12.9 1.45 0.656 0.0274 1.562 4.25 1.17 15.4 PRS_PLINK_0.00398107170553497 TRUE 228 Hemangioma and lymphangioma, any site Both 547 2534 2 neoplasms darkcyan 2534, 547 633, 145 633, 109 633, 137 634, 156 0.0232 0.0495 0.64 0.1938 1.02 0.929 1.13 -0.276 0.14 0.0485 1.314 0.759 0.577 0.998 -0.0336 0.135 0.803 0.09548 0.967 0.743 1.26 0.0578 0.133 0.664 0.1775 1.06 0.816 1.38 PRS_PLINK_0.00398107170553497 FALSE 228.1 Hemangioma of skin and subcutaneous tissue Both 386 1664 2 neoplasms darkcyan 1664, 386 415, 106 416, 67 416, 105 416, 108 0.0285 0.0592 0.631 0.2001 1.03 0.916 1.16 -0.468 0.173 0.00675 2.171 0.626 0.446 0.879 -0.0194 0.158 0.902 0.04473 0.981 0.72 1.34 -0.00537 0.159 0.973 0.01183 0.995 0.728 1.36 PRS_PLINK_0.00398107170553497 FALSE 229 Benign neoplasm of unspecified sites Both 745 4040 2 neoplasms darkcyan 4040, 745 1009, 192 1010, 186 1010, 173 1010, 194 0.00617 0.0412 0.881 0.05497 1.01 0.928 1.09 -0.0557 0.114 0.624 0.2047 0.946 0.757 1.18 -0.126 0.118 0.285 0.545 0.882 0.701 1.11 0.00327 0.116 0.977 0.009904 1 0.8 1.26 PRS_PLINK_0.00398107170553497 FALSE 229.1 Benign neoplasm of lymph nodes Both 434 3754 2 neoplasms darkcyan 3754, 434 938, 116 938, 108 938, 101 939, 109 -0.0335 0.0522 0.521 0.2835 0.967 0.873 1.07 -0.0909 0.142 0.523 0.2818 0.913 0.691 1.21 -0.158 0.147 0.281 0.5517 0.854 0.64 1.14 -0.101 0.146 0.49 0.3097 0.904 0.679 1.2 PRS_PLINK_0.00398107170553497 FALSE 240 Simple and unspecified goiter Both 237 1459 3 endocrine/metabolic brown 1459, 237 365, 52 365, 69 364, 52 365, 64 0.0484 0.0732 0.509 0.2936 1.05 0.909 1.21 0.298 0.199 0.134 0.8732 1.35 0.912 1.99 0.0133 0.212 0.95 0.02217 1.01 0.668 1.54 0.26 0.208 0.211 0.6749 1.3 0.863 1.95 PRS_PLINK_0.00398107170553497 FALSE 241 Nontoxic nodular goiter Both 523 2775 3 endocrine/metabolic brown 2775, 523 694, 126 694, 146 693, 108 694, 143 0.0345 0.0489 0.48 0.319 1.04 0.941 1.14 0.164 0.134 0.221 0.6563 1.18 0.906 1.53 -0.103 0.146 0.481 0.3182 0.902 0.678 1.2 0.181 0.139 0.191 0.718 1.2 0.913 1.57 PRS_PLINK_0.00398107170553497 FALSE 241.1 Nontoxic uninodular goiter Both 427 2565 3 endocrine/metabolic brown 2565, 427 642, 100 641, 124 641, 93 641, 110 0.0227 0.0535 0.671 0.1733 1.02 0.921 1.14 0.217 0.146 0.138 0.8613 1.24 0.933 1.66 -0.026 0.159 0.87 0.06036 0.974 0.714 1.33 0.126 0.155 0.416 0.3809 1.13 0.837 1.54 PRS_PLINK_0.00398107170553497 FALSE 241.2 Nontoxic multinodular goiter Both 233 1781 3 endocrine/metabolic brown 1781, 233 446, 52 445, 62 445, 45 445, 74 0.0861 0.0726 0.236 0.6277 1.09 0.945 1.26 0.143 0.199 0.473 0.3251 1.15 0.78 1.71 -0.131 0.215 0.543 0.2649 0.877 0.575 1.34 0.339 0.198 0.0864 1.064 1.4 0.953 2.07 PRS_PLINK_0.00398107170553497 FALSE 242 Thyrotoxicosis with or without goiter Both 292 1835 3 endocrine/metabolic brown 1835, 292 459, 83 459, 77 458, 63 459, 69 -0.0858 0.0653 0.189 0.724 0.918 0.808 1.04 -0.0857 0.172 0.619 0.2084 0.918 0.655 1.29 -0.247 0.184 0.179 0.7478 0.781 0.545 1.12 -0.234 0.181 0.197 0.7051 0.792 0.555 1.13 PRS_PLINK_0.00398107170553497 FALSE 242.1 Graves' disease Both 100 690 3 endocrine/metabolic brown 690, 100 173, 31 172, 27 172, 20 173, 22 -0.173 0.114 0.13 0.8856 0.842 0.673 1.05 -0.189 0.287 0.511 0.2914 0.828 0.471 1.45 -0.561 0.321 0.0811 1.091 0.571 0.304 1.07 -0.517 0.315 0.1 0.9988 0.596 0.322 1.1 PRS_PLINK_0.00398107170553497 FALSE 242.2 Toxic multinodular goiter Both 23 177 3 endocrine/metabolic brown 177, 23 45, 3 44, 8 44, 5 44, 7 0.151 0.214 0.478 0.3202 1.16 0.766 1.77 1.24 0.7 0.0769 1.114 3.45 0.875 13.6 0.522 0.706 0.46 0.3372 1.69 0.422 6.73 0.585 0.697 0.402 0.3962 1.79 0.458 7.04 PRS_PLINK_0.00398107170553497 TRUE 242.3 Exophthalmos Both 56 358 3 endocrine/metabolic brown 358, 56 90, 18 89, 14 89, 11 90, 13 -0.116 0.142 0.415 0.3823 0.891 0.675 1.18 -0.251 0.387 0.517 0.2865 0.778 0.364 1.66 -0.399 0.414 0.335 0.4744 0.671 0.298 1.51 -0.49 0.407 0.229 0.6408 0.613 0.276 1.36 PRS_PLINK_0.00398107170553497 FALSE 242.31 Thyrotoxic exophthalmos Both 28 184 3 endocrine/metabolic brown 184, 28 46, 10 46, 5 46, 8 46, 5 -0.144 0.201 0.474 0.3239 0.866 0.584 1.28 -0.399 0.584 0.494 0.3065 0.671 0.214 2.11 -0.174 0.586 0.767 0.1152 0.841 0.267 2.65 -0.753 0.62 0.225 0.6486 0.471 0.14 1.59 PRS_PLINK_0.00398107170553497 TRUE 244 Hypothyroidism Both 1270 3352 3 endocrine/metabolic brown 3352, 1270 838, 326 838, 338 838, 318 838, 287 0.00623 0.035 0.859 0.06617 1.01 0.94 1.08 0.0784 0.0952 0.41 0.3868 1.08 0.897 1.3 0.0687 0.0984 0.485 0.3141 1.07 0.883 1.3 -0.0407 0.101 0.687 0.1631 0.96 0.788 1.17 PRS_PLINK_0.00398107170553497 FALSE 244.1 Secondary hypothyroidism Both 250 2129 3 endocrine/metabolic brown 2129, 250 533, 67 532, 61 532, 60 532, 62 -0.0444 0.0681 0.515 0.2882 0.957 0.837 1.09 -0.0289 0.189 0.879 0.05622 0.972 0.67 1.41 -0.0796 0.195 0.683 0.1655 0.923 0.63 1.35 -0.129 0.197 0.513 0.2903 0.879 0.597 1.29 PRS_PLINK_0.00398107170553497 FALSE 244.2 Acquired hypothyroidism Both 254 1626 3 endocrine/metabolic brown 1626, 254 407, 69 406, 67 406, 64 407, 53 -0.0652 0.068 0.337 0.4721 0.937 0.82 1.07 -0.0146 0.186 0.937 0.02804 0.986 0.685 1.42 0.0236 0.192 0.903 0.04453 1.02 0.702 1.49 -0.227 0.202 0.26 0.5848 0.797 0.536 1.18 PRS_PLINK_0.00398107170553497 FALSE 244.4 Hypothyroidism NOS Both 1224 3322 3 endocrine/metabolic brown 3322, 1224 831, 317 830, 324 830, 301 831, 281 0.00597 0.0355 0.867 0.06212 1.01 0.938 1.08 0.0711 0.0965 0.461 0.3362 1.07 0.889 1.3 0.0541 0.1 0.589 0.2299 1.06 0.868 1.28 -0.0325 0.102 0.75 0.1247 0.968 0.792 1.18 PRS_PLINK_0.00398107170553497 FALSE 245 Thyroiditis Both 166 1167 3 endocrine/metabolic brown 1167, 166 292, 38 292, 52 291, 37 292, 39 0.0198 0.0856 0.817 0.08776 1.02 0.862 1.21 0.324 0.229 0.156 0.8063 1.38 0.883 2.17 0.124 0.251 0.621 0.2067 1.13 0.692 1.85 0.0266 0.256 0.917 0.03752 1.03 0.622 1.7 PRS_PLINK_0.00398107170553497 FALSE 245.2 Chronic thyroiditis Both 136 1029 3 endocrine/metabolic brown 1029, 136 258, 32 257, 39 257, 33 257, 32 0.00611 0.0927 0.947 0.02345 1.01 0.839 1.21 0.152 0.253 0.546 0.2624 1.16 0.71 1.91 0.142 0.268 0.596 0.2248 1.15 0.682 1.95 -0.0101 0.275 0.971 0.01291 0.99 0.578 1.7 PRS_PLINK_0.00398107170553497 FALSE 245.21 Chronic lymphocytic thyroiditis Both 136 1016 3 endocrine/metabolic brown 1016, 136 254, 31 254, 37 254, 36 254, 32 0.0171 0.0931 0.854 0.06841 1.02 0.848 1.22 0.133 0.257 0.606 0.2178 1.14 0.69 1.89 0.254 0.266 0.339 0.4695 1.29 0.766 2.17 0.0188 0.277 0.946 0.02411 1.02 0.592 1.75 PRS_PLINK_0.00398107170553497 FALSE 246 Other disorders of thyroid Both 967 3192 3 endocrine/metabolic brown 3192, 967 798, 242 798, 247 798, 255 798, 222 0.00892 0.0389 0.819 0.08683 1.01 0.935 1.09 0.0698 0.107 0.515 0.2884 1.07 0.869 1.32 0.178 0.109 0.102 0.9904 1.19 0.965 1.48 0.0191 0.113 0.865 0.06275 1.02 0.817 1.27 PRS_PLINK_0.00398107170553497 FALSE 246.2 Thyroid cyst Both 26 117 3 endocrine/metabolic brown 117, 26 30, 4 29, 8 29, 8 29, 6 0.0959 0.26 0.713 0.1472 1.1 0.661 1.83 0.618 0.636 0.331 0.4799 1.85 0.534 6.45 0.632 0.675 0.349 0.4569 1.88 0.501 7.06 0.875 0.789 0.267 0.5727 2.4 0.511 11.3 PRS_PLINK_0.00398107170553497 TRUE 246.7 Abnormal results of function study of thyroid Both 213 1212 3 endocrine/metabolic brown 1212, 213 303, 61 303, 53 303, 44 303, 55 0.000499 0.0748 0.995 0.002319 1 0.864 1.16 -0.112 0.208 0.589 0.23 0.894 0.595 1.34 -0.252 0.222 0.256 0.5915 0.777 0.503 1.2 -0.0295 0.21 0.888 0.05138 0.971 0.643 1.47 PRS_PLINK_0.00398107170553497 FALSE 249 Secondary diabetes mellitus Both 146 720 3 endocrine/metabolic brown 720, 146 180, 45 180, 41 180, 25 180, 35 -0.181 0.11 0.102 0.9934 0.835 0.672 1.04 -0.0985 0.295 0.739 0.1316 0.906 0.508 1.62 -0.587 0.331 0.0765 1.116 0.556 0.291 1.06 -0.283 0.3 0.345 0.4619 0.753 0.418 1.36 PRS_PLINK_0.00398107170553497 FALSE 250 Diabetes mellitus Both 1962 3223 3 endocrine/metabolic brown 3223, 1962 805, 475 806, 526 805, 478 806, 483 -0.00351 0.0326 0.914 0.03892 0.996 0.935 1.06 0.15 0.0901 0.0959 1.018 1.16 0.974 1.39 0.0794 0.0934 0.396 0.4027 1.08 0.901 1.3 0.067 0.0945 0.478 0.3204 1.07 0.889 1.29 PRS_PLINK_0.00398107170553497 FALSE 250.1 Type 1 diabetes Both 536 1157 3 endocrine/metabolic brown 1157, 536 290, 148 289, 146 289, 114 289, 128 -0.0944 0.0772 0.221 0.6548 0.91 0.782 1.06 0.0637 0.222 0.774 0.111 1.07 0.69 1.65 -0.0274 0.238 0.909 0.04167 0.973 0.61 1.55 0.00393 0.226 0.986 0.006078 1 0.645 1.56 PRS_PLINK_0.00398107170553497 FALSE 250.11 Type 1 diabetes with ketoacidosis Both 105 86 3 endocrine/metabolic brown 86, 105 22, 28 21, 31 21, 26 22, 20 -0.19 0.183 0.299 0.5241 0.827 0.578 1.18 -0.0935 0.531 0.86 0.0653 0.911 0.321 2.58 0.0701 0.586 0.905 0.04352 1.07 0.34 3.38 -0.494 0.56 0.378 0.4229 0.61 0.203 1.83 PRS_PLINK_0.00398107170553497 FALSE 250.12 Type 1 diabetes with renal manifestations Both 166 267 3 endocrine/metabolic brown 267, 166 67, 39 67, 40 66, 40 67, 47 -0.0729 0.126 0.562 0.2502 0.93 0.727 1.19 -0.168 0.397 0.672 0.1723 0.846 0.389 1.84 -0.18 0.416 0.666 0.1765 0.836 0.37 1.89 -5.06e-05 0.359 1 4.884e-05 1 0.495 2.02 PRS_PLINK_0.00398107170553497 FALSE 250.13 Type 1 diabetes with ophthalmic manifestations Both 245 292 3 endocrine/metabolic brown 292, 245 73, 68 73, 59 73, 55 73, 63 -0.0979 0.12 0.416 0.3806 0.907 0.716 1.15 -0.206 0.368 0.577 0.2392 0.814 0.396 1.68 -0.112 0.393 0.776 0.11 0.894 0.414 1.93 -0.301 0.361 0.405 0.3921 0.74 0.365 1.5 PRS_PLINK_0.00398107170553497 FALSE 250.14 Type 1 diabetes with neurological manifestations Both 193 246 3 endocrine/metabolic brown 246, 193 62, 54 61, 48 61, 50 62, 41 -0.159 0.126 0.208 0.6823 0.853 0.667 1.09 -0.14 0.358 0.696 0.1575 0.869 0.431 1.75 -0.185 0.368 0.616 0.2103 0.831 0.404 1.71 -0.57 0.379 0.132 0.8794 0.565 0.269 1.19 PRS_PLINK_0.00398107170553497 FALSE 250.15 Diabetes type 1 with peripheral circulatory disorders Both 47 84 3 endocrine/metabolic brown 84, 47 21, 12 21, 14 21, 10 21, 11 -0.0876 0.231 0.705 0.1518 0.916 0.582 1.44 0.281 0.61 0.646 0.19 1.32 0.4 4.38 -0.584 0.663 0.379 0.4217 0.558 0.152 2.05 -0.14 0.627 0.824 0.08424 0.87 0.254 2.97 PRS_PLINK_0.00398107170553497 TRUE 250.2 Type 2 diabetes Both 1026 3064 3 endocrine/metabolic brown 3064, 1026 765, 265 766, 271 766, 241 766, 249 -0.038 0.0444 0.392 0.4064 0.963 0.882 1.05 0.116 0.123 0.348 0.4581 1.12 0.882 1.43 0.0195 0.129 0.88 0.05574 1.02 0.792 1.31 -0.00448 0.13 0.972 0.01212 0.996 0.772 1.28 PRS_PLINK_0.00398107170553497 FALSE 250.21 Type 2 diabetes with ketoacidosis Both 81 118 3 endocrine/metabolic brown 118, 81 30, 26 29, 15 29, 23 30, 17 -0.277 0.187 0.14 0.8546 0.758 0.525 1.09 -1.65 0.787 0.0355 1.45 0.191 0.0409 0.894 -0.438 0.511 0.392 0.4072 0.645 0.237 1.76 -0.988 0.533 0.0639 1.195 0.372 0.131 1.06 PRS_PLINK_0.00398107170553497 FALSE 250.22 Type 2 diabetes with renal manifestations Both 169 1283 3 endocrine/metabolic brown 1283, 169 321, 46 321, 35 320, 38 321, 50 -0.0563 0.0965 0.56 0.2519 0.945 0.782 1.14 -0.28 0.284 0.325 0.4886 0.756 0.433 1.32 -2e-04 0.28 0.999 0.0002469 1 0.577 1.73 -0.0329 0.272 0.904 0.04388 0.968 0.567 1.65 PRS_PLINK_0.00398107170553497 FALSE 250.23 Type 2 diabetes with ophthalmic manifestations Both 280 984 3 endocrine/metabolic brown 984, 280 246, 90 246, 61 246, 63 246, 66 -0.169 0.0905 0.0617 1.209 0.845 0.707 1.01 -0.0682 0.252 0.786 0.1043 0.934 0.57 1.53 -0.153 0.266 0.564 0.2486 0.858 0.51 1.44 -0.345 0.273 0.205 0.6876 0.708 0.415 1.21 PRS_PLINK_0.00398107170553497 FALSE 250.24 Type 2 diabetes with neurological manifestations Both 278 1601 3 endocrine/metabolic brown 1601, 278 401, 72 400, 65 400, 67 400, 74 -0.0847 0.0845 0.316 0.5003 0.919 0.779 1.08 -0.142 0.237 0.548 0.2609 0.868 0.546 1.38 -0.0493 0.238 0.836 0.07789 0.952 0.597 1.52 -0.189 0.238 0.428 0.3685 0.828 0.519 1.32 PRS_PLINK_0.00398107170553497 FALSE 250.25 Diabetes type 2 with peripheral circulatory disorders Both 62 522 3 endocrine/metabolic brown 522, 62 131, 18 130, 11 130, 18 131, 15 -0.144 0.167 0.387 0.4125 0.866 0.625 1.2 -0.1 0.475 0.833 0.07946 0.905 0.357 2.29 0.0839 0.433 0.846 0.07241 1.09 0.465 2.54 -0.0388 0.472 0.934 0.02945 0.962 0.382 2.42 PRS_PLINK_0.00398107170553497 FALSE 250.3 Insulin pump user Both 476 2026 3 endocrine/metabolic brown 2026, 476 506, 133 506, 123 506, 106 507, 114 -0.129 0.0755 0.0884 1.054 0.879 0.758 1.02 0.0493 0.205 0.81 0.09173 1.05 0.703 1.57 -0.0606 0.22 0.783 0.1065 0.941 0.612 1.45 -0.163 0.219 0.456 0.3411 0.85 0.554 1.3 PRS_PLINK_0.00398107170553497 FALSE 250.4 Abnormal glucose Both 1632 3163 3 endocrine/metabolic brown 3163, 1632 790, 387 791, 438 790, 400 791, 407 0.0197 0.0349 0.573 0.2422 1.02 0.952 1.09 0.173 0.0973 0.0761 1.119 1.19 0.982 1.44 0.111 0.101 0.269 0.5699 1.12 0.917 1.36 0.12 0.101 0.235 0.6292 1.13 0.925 1.38 PRS_PLINK_0.00398107170553497 FALSE 250.41 Impaired fasting glucose Both 400 1853 3 endocrine/metabolic brown 1853, 400 464, 93 463, 100 463, 98 463, 109 -0.00333 0.06 0.956 0.01965 0.997 0.886 1.12 0.107 0.168 0.526 0.2793 1.11 0.8 1.55 0.121 0.171 0.481 0.3177 1.13 0.807 1.58 0.133 0.171 0.438 0.3587 1.14 0.817 1.6 PRS_PLINK_0.00398107170553497 FALSE 250.42 Other abnormal glucose Both 1446 3118 3 endocrine/metabolic brown 3118, 1446 779, 342 779, 387 779, 356 780, 361 0.0261 0.0369 0.48 0.3189 1.03 0.955 1.1 0.199 0.103 0.0531 1.275 1.22 0.997 1.49 0.141 0.107 0.186 0.7303 1.15 0.934 1.42 0.139 0.107 0.194 0.7126 1.15 0.932 1.42 PRS_PLINK_0.00398107170553497 FALSE 250.5 Glycosuria or Acetonuria Both 25 120 3 endocrine/metabolic brown 120, 25 30, 6 30, 6 30, 5 30, 8 0.023 0.27 0.932 0.03043 1.02 0.602 1.74 -0.0267 0.682 0.969 0.01375 0.974 0.256 3.71 0.212 0.808 0.794 0.1004 1.24 0.253 6.03 0.335 0.82 0.683 0.1655 1.4 0.28 6.97 PRS_PLINK_0.00398107170553497 TRUE 250.6 Polyneuropathy in diabetes Both 256 1252 3 endocrine/metabolic brown 1252, 256 313, 75 313, 57 313, 63 313, 61 -0.171 0.091 0.0604 1.219 0.843 0.705 1.01 -0.382 0.259 0.141 0.8505 0.683 0.411 1.14 -0.0676 0.25 0.787 0.1042 0.935 0.573 1.53 -0.425 0.263 0.106 0.9759 0.654 0.391 1.09 PRS_PLINK_0.00398107170553497 FALSE 250.7 Diabetic retinopathy Both 318 1029 3 endocrine/metabolic brown 1029, 318 258, 100 257, 70 257, 71 257, 77 -0.0592 0.0691 0.391 0.4073 0.943 0.823 1.08 -0.208 0.197 0.291 0.5366 0.812 0.551 1.2 -0.239 0.197 0.224 0.6497 0.787 0.536 1.16 -0.116 0.199 0.558 0.253 0.89 0.603 1.31 PRS_PLINK_0.00398107170553497 FALSE 251 Other disorders of pancreatic internal secretion Both 195 1049 3 endocrine/metabolic brown 1049, 195 263, 49 262, 42 262, 49 262, 55 0.0341 0.0776 0.66 0.1801 1.03 0.889 1.2 -0.0764 0.228 0.737 0.1324 0.926 0.593 1.45 0.0136 0.224 0.951 0.02163 1.01 0.654 1.57 0.168 0.219 0.444 0.3525 1.18 0.77 1.82 PRS_PLINK_0.00398107170553497 FALSE 251.1 Hypoglycemia Both 271 870 3 endocrine/metabolic brown 870, 271 218, 71 217, 71 217, 61 218, 68 -0.117 0.0829 0.159 0.7978 0.89 0.756 1.05 -0.126 0.239 0.599 0.2223 0.882 0.552 1.41 -0.282 0.254 0.266 0.5755 0.754 0.458 1.24 -0.193 0.242 0.425 0.3719 0.824 0.513 1.32 PRS_PLINK_0.00398107170553497 FALSE 252 Disorders of parathyroid gland Both 368 2743 3 endocrine/metabolic brown 2743, 368 685, 88 686, 95 685, 89 686, 96 0.051 0.0574 0.375 0.4265 1.05 0.94 1.18 0.104 0.158 0.51 0.2925 1.11 0.814 1.51 0.0393 0.163 0.809 0.09208 1.04 0.756 1.43 0.171 0.163 0.293 0.5332 1.19 0.862 1.63 PRS_PLINK_0.00398107170553497 FALSE 252.1 Hyperparathyroidism Both 342 2549 3 endocrine/metabolic brown 2549, 342 637, 81 637, 90 637, 86 637, 85 0.0318 0.0596 0.594 0.2263 1.03 0.918 1.16 0.13 0.164 0.427 0.3696 1.14 0.826 1.57 0.0795 0.168 0.636 0.1968 1.08 0.779 1.5 0.123 0.171 0.471 0.3271 1.13 0.809 1.58 PRS_PLINK_0.00398107170553497 FALSE 252.2 Hypoparathyroidism Both 75 615 3 endocrine/metabolic brown 615, 75 154, 18 154, 18 153, 22 154, 17 -0.00714 0.123 0.954 0.02056 0.993 0.78 1.26 -0.144 0.36 0.689 0.1617 0.866 0.427 1.75 0.103 0.341 0.762 0.118 1.11 0.569 2.16 0.0314 0.359 0.93 0.03138 1.03 0.51 2.09 PRS_PLINK_0.00398107170553497 FALSE 253 Disorders of the pituitary gland and its hypothalamic control Both 98 918 3 endocrine/metabolic brown 918, 98 230, 29 229, 18 229, 22 230, 29 -0.0489 0.106 0.644 0.1908 0.952 0.774 1.17 -0.412 0.31 0.184 0.7346 0.662 0.361 1.22 -0.266 0.297 0.37 0.4321 0.766 0.428 1.37 -0.0575 0.287 0.841 0.07503 0.944 0.538 1.66 PRS_PLINK_0.00398107170553497 FALSE 253.1 Pituitary hyperfunction Both 27 335 3 endocrine/metabolic brown 335, 27 84, 7 84, 8 83, 6 84, 6 -0.00998 0.19 0.958 0.01864 0.99 0.683 1.44 0.201 0.501 0.688 0.1621 1.22 0.458 3.26 -0.0476 0.526 0.928 0.03251 0.954 0.34 2.67 0.0951 0.571 0.868 0.06165 1.1 0.359 3.37 PRS_PLINK_0.00398107170553497 TRUE 253.11 Acromegaly and gigantism Both 2 87 3 endocrine/metabolic brown 87, 2 22, 0 22, 1 21, 1 22, 0 -0.45 0.538 0.403 0.395 0.638 0.222 1.83 0.723 1.26 0.567 0.2462 2.06 0.173 24.5 0.54 1.26 0.667 0.1758 1.72 0.147 20.1 0.163 1.18 0.891 0.05029 1.18 0.116 12 PRS_PLINK_0.00398107170553497 TRUE 253.2 Pituitary hypofunction Both 14 194 3 endocrine/metabolic brown 194, 14 49, 3 48, 5 48, 3 49, 3 -0.0831 0.251 0.741 0.1305 0.92 0.563 1.5 0.726 0.707 0.305 0.5162 2.07 0.517 8.27 0.74 0.791 0.35 0.4565 2.1 0.445 9.88 -0.0126 0.789 0.987 0.00555 0.988 0.21 4.64 PRS_PLINK_0.00398107170553497 TRUE 253.3 Diabetes insipidus Both 10 103 3 endocrine/metabolic brown 103, 10 26, 3 26, 4 25, 2 26, 1 -0.225 0.3 0.452 0.3444 0.798 0.444 1.44 0.861 0.859 0.316 0.5005 2.37 0.44 12.7 -0.294 0.901 0.744 0.1286 0.745 0.127 4.35 -0.852 1.1 0.438 0.3586 0.427 0.0496 3.67 PRS_PLINK_0.00398107170553497 TRUE 253.4 Anterior pituitary disorders Both 14 102 3 endocrine/metabolic brown 102, 14 26, 6 25, 2 25, 1 26, 5 -0.25 0.286 0.382 0.4175 0.779 0.445 1.36 -0.434 0.787 0.581 0.2356 0.648 0.139 3.03 -1.18 0.9 0.19 0.7208 0.307 0.0526 1.8 0.0269 0.722 0.97 0.0131 1.03 0.249 4.23 PRS_PLINK_0.00398107170553497 TRUE 253.7 Other disorders of neurohypophysis Both 24 93 3 endocrine/metabolic brown 93, 24 24, 7 23, 3 23, 8 23, 6 -0.00604 0.237 0.98 0.008917 0.994 0.625 1.58 -0.499 0.785 0.525 0.2799 0.607 0.13 2.83 -0.138 0.677 0.839 0.07634 0.871 0.231 3.28 0.167 0.707 0.813 0.08989 1.18 0.296 4.73 PRS_PLINK_0.00398107170553497 TRUE 255 Disorders of adrenal glands Both 204 1747 3 endocrine/metabolic brown 1747, 204 437, 64 437, 47 436, 55 437, 38 -0.142 0.0748 0.057 1.244 0.867 0.749 1 -0.306 0.204 0.135 0.8707 0.737 0.493 1.1 -0.197 0.201 0.327 0.4853 0.822 0.555 1.22 -0.493 0.221 0.0257 1.59 0.611 0.396 0.942 PRS_PLINK_0.00398107170553497 FALSE 255.1 Adrenal hyperfunction Both 46 460 3 endocrine/metabolic brown 460, 46 115, 14 115, 12 115, 16 115, 4 -0.285 0.152 0.0606 1.218 0.752 0.559 1.01 -0.154 0.405 0.704 0.1527 0.857 0.388 1.89 0.191 0.395 0.629 0.2014 1.21 0.558 2.62 -1.07 0.527 0.0416 1.381 0.341 0.121 0.96 PRS_PLINK_0.00398107170553497 TRUE 255.11 Cushing's syndrome Both 18 229 3 endocrine/metabolic brown 229, 18 58, 6 57, 7 57, 4 57, 1 -0.393 0.252 0.119 0.9256 0.675 0.412 1.11 0.157 0.546 0.774 0.111 1.17 0.401 3.41 -0.319 0.639 0.618 0.2093 0.727 0.208 2.54 -1.16 0.782 0.139 0.8556 0.315 0.0679 1.46 PRS_PLINK_0.00398107170553497 TRUE 255.12 Hyperaldosteronism Both 10 157 3 endocrine/metabolic brown 157, 10 40, 1 39, 3 39, 4 39, 2 0.416 0.339 0.22 0.6577 1.52 0.78 2.95 0.936 0.928 0.313 0.5045 2.55 0.414 15.7 1.01 0.845 0.23 0.6374 2.76 0.526 14.5 -0.372 0.978 0.703 0.1529 0.689 0.101 4.68 PRS_PLINK_0.00398107170553497 TRUE 255.2 Adrenal hypofunction Both 103 757 3 endocrine/metabolic brown 757, 103 190, 31 189, 26 189, 23 189, 23 -0.0573 0.104 0.581 0.2359 0.944 0.771 1.16 -0.159 0.281 0.572 0.2428 0.853 0.491 1.48 -0.245 0.292 0.401 0.3965 0.783 0.442 1.39 -0.192 0.299 0.522 0.2826 0.826 0.459 1.48 PRS_PLINK_0.00398107170553497 FALSE 255.21 Glucocorticoid deficiency Both 99 709 3 endocrine/metabolic brown 709, 99 178, 29 177, 24 177, 23 177, 23 -0.0502 0.107 0.64 0.1938 0.951 0.771 1.17 -0.168 0.292 0.564 0.2485 0.845 0.477 1.5 -0.246 0.299 0.41 0.3871 0.782 0.435 1.4 -0.147 0.307 0.632 0.1991 0.863 0.473 1.58 PRS_PLINK_0.00398107170553497 FALSE 256 Ovarian dysfunction Female 231 1520 3 endocrine/metabolic brown 1520, 231 380, 60 380, 57 380, 54 380, 60 0.00918 0.0716 0.898 0.04672 1.01 0.877 1.16 -0.0588 0.199 0.768 0.1149 0.943 0.638 1.39 -0.149 0.203 0.464 0.3333 0.862 0.579 1.28 -0.0794 0.202 0.694 0.1587 0.924 0.622 1.37 PRS_PLINK_0.00398107170553497 FALSE 256.4 Polycystic ovaries Female 121 975 3 endocrine/metabolic brown 975, 121 244, 26 244, 29 243, 35 244, 31 0.0458 0.0975 0.639 0.1947 1.05 0.865 1.27 0.112 0.281 0.69 0.1612 1.12 0.644 1.94 0.235 0.278 0.397 0.4012 1.27 0.734 2.18 0.0325 0.288 0.91 0.0409 1.03 0.587 1.82 PRS_PLINK_0.00398107170553497 FALSE 257 Testicular dysfunction Male 79 494 3 endocrine/metabolic brown 494, 79 124, 16 123, 22 123, 14 124, 27 0.197 0.128 0.124 0.9051 1.22 0.947 1.56 0.369 0.356 0.301 0.5217 1.45 0.719 2.91 -0.127 0.384 0.742 0.1299 0.881 0.415 1.87 0.474 0.349 0.175 0.758 1.61 0.81 3.19 PRS_PLINK_0.00398107170553497 FALSE 257.1 Testicular hypofunction Male 78 475 3 endocrine/metabolic brown 475, 78 119, 15 119, 22 118, 14 119, 27 0.18 0.127 0.157 0.8029 1.2 0.933 1.54 0.406 0.362 0.262 0.5818 1.5 0.738 3.05 -0.0486 0.392 0.901 0.04511 0.953 0.441 2.06 0.562 0.36 0.119 0.9261 1.75 0.866 3.55 PRS_PLINK_0.00398107170553497 FALSE 258 Iatrogenic endocrine disorders Both 13 97 3 endocrine/metabolic brown 97, 13 25, 3 24, 6 24, 1 24, 3 -0.103 0.293 0.726 0.1388 0.903 0.508 1.6 -0.093 0.775 0.904 0.0436 0.911 0.2 4.16 -0.377 0.931 0.686 0.1639 0.686 0.111 4.25 0.0438 0.797 0.956 0.01948 1.04 0.219 4.98 PRS_PLINK_0.00398107170553497 TRUE 258.1 Postablative ovarian failure Female 23 152 3 endocrine/metabolic brown 152, 23 38, 5 38, 6 38, 7 38, 5 -0.149 0.245 0.542 0.2656 0.861 0.533 1.39 0.259 0.627 0.679 0.1679 1.3 0.379 4.43 0.404 0.608 0.507 0.2954 1.5 0.455 4.93 0.0998 0.66 0.88 0.05567 1.1 0.303 4.03 PRS_PLINK_0.00398107170553497 TRUE 259 Other endocrine disorders Both 198 1201 3 endocrine/metabolic brown 1201, 198 301, 48 300, 49 300, 46 300, 55 -0.0129 0.0796 0.872 0.05962 0.987 0.845 1.15 0.0418 0.22 0.849 0.07099 1.04 0.677 1.6 -0.0919 0.225 0.683 0.1654 0.912 0.587 1.42 0.163 0.223 0.465 0.3322 1.18 0.76 1.82 PRS_PLINK_0.00398107170553497 FALSE 260 Protein-calorie malnutrition Both 309 2245 3 endocrine/metabolic brown 2245, 309 561, 87 561, 80 561, 74 561, 68 -0.0843 0.062 0.173 0.7608 0.919 0.814 1.04 -0.11 0.167 0.509 0.293 0.896 0.645 1.24 -0.169 0.172 0.326 0.4873 0.844 0.602 1.18 -0.273 0.179 0.126 0.8996 0.761 0.536 1.08 PRS_PLINK_0.00398107170553497 FALSE 260.1 Cachexia Both 28 208 3 endocrine/metabolic brown 208, 28 52, 3 52, 7 52, 10 52, 8 0.432 0.225 0.0556 1.255 1.54 0.99 2.39 0.59 0.659 0.371 0.4311 1.8 0.496 6.57 1.3 0.675 0.0533 1.273 3.68 0.982 13.8 0.894 0.82 0.276 0.5597 2.44 0.49 12.2 PRS_PLINK_0.00398107170553497 TRUE 260.2 severe protein-calorie malnutrition Both 158 1348 3 endocrine/metabolic brown 1348, 158 336, 43 337, 38 337, 43 337, 34 -0.0307 0.0859 0.721 0.1421 0.97 0.819 1.15 -0.13 0.234 0.579 0.2376 0.878 0.554 1.39 -0.00873 0.233 0.97 0.01321 0.991 0.628 1.56 -0.274 0.25 0.274 0.5623 0.76 0.466 1.24 PRS_PLINK_0.00398107170553497 FALSE 260.22 Nutritional marasmus Both 58 529 3 endocrine/metabolic brown 529, 58 132, 15 132, 13 132, 16 132, 14 0.0431 0.144 0.765 0.1162 1.04 0.787 1.39 -0.168 0.383 0.66 0.1802 0.845 0.399 1.79 0.0531 0.374 0.887 0.05204 1.05 0.507 2.19 -0.0542 0.396 0.891 0.05008 0.947 0.436 2.06 PRS_PLINK_0.00398107170553497 FALSE 260.3 Adult failure to thrive Both 61 515 3 endocrine/metabolic brown 515, 61 129, 13 129, 18 128, 11 129, 19 0.167 0.13 0.198 0.7023 1.18 0.916 1.53 0.305 0.383 0.426 0.3708 1.36 0.641 2.87 -0.0679 0.418 0.871 0.05997 0.934 0.412 2.12 0.414 0.384 0.282 0.55 1.51 0.712 3.21 PRS_PLINK_0.00398107170553497 FALSE 260.6 Anorexia Both 119 773 3 endocrine/metabolic brown 773, 119 194, 33 193, 34 193, 29 193, 23 -0.0815 0.0993 0.412 0.3854 0.922 0.759 1.12 0.0156 0.265 0.953 0.02097 1.02 0.605 1.71 -0.13 0.276 0.639 0.1946 0.879 0.511 1.51 -0.435 0.297 0.143 0.8446 0.647 0.362 1.16 PRS_PLINK_0.00398107170553497 FALSE 260.7 Polyphagia Both 12 121 3 endocrine/metabolic brown 121, 12 31, 3 30, 5 30, 2 30, 2 -0.263 0.291 0.366 0.4361 0.769 0.434 1.36 0.115 0.769 0.881 0.0548 1.12 0.249 5.06 -2.06 1.41 0.144 0.8402 0.127 0.00799 2.03 -0.487 0.823 0.554 0.2567 0.614 0.122 3.08 PRS_PLINK_0.00398107170553497 TRUE 261 Vitamin deficiency Both 1671 3132 3 endocrine/metabolic brown 3132, 1671 782, 407 783, 436 783, 407 783, 421 0.0365 0.0318 0.25 0.6021 1.04 0.975 1.1 0.0795 0.0882 0.367 0.4351 1.08 0.911 1.29 0.0265 0.0908 0.771 0.1132 1.03 0.859 1.23 0.0957 0.091 0.293 0.5333 1.1 0.921 1.32 PRS_PLINK_0.00398107170553497 FALSE 261.1 Vitamin A deficiency Both 6 86 3 endocrine/metabolic brown 86, 6 22, 0 21, 1 21, 3 22, 2 1.01 0.574 0.0789 1.103 2.74 0.89 8.44 0.225 1.39 0.872 0.05945 1.25 0.0814 19.3 1.28 1.42 0.37 0.4315 3.58 0.22 58.2 0.857 1.22 0.484 0.3153 2.36 0.214 26 PRS_PLINK_0.00398107170553497 TRUE 261.2 Vitamin B-complex deficiencies Both 165 899 3 endocrine/metabolic brown 899, 165 225, 31 225, 39 224, 52 225, 43 0.1 0.0874 0.253 0.5976 1.11 0.931 1.31 0.27 0.259 0.297 0.5269 1.31 0.789 2.17 0.459 0.248 0.0643 1.192 1.58 0.973 2.57 0.299 0.262 0.254 0.5956 1.35 0.807 2.25 PRS_PLINK_0.00398107170553497 FALSE 261.4 Vitamin D deficiency Both 1606 3134 3 endocrine/metabolic brown 3134, 1606 783, 391 783, 426 783, 383 784, 406 0.036 0.0322 0.263 0.5805 1.04 0.973 1.1 0.0967 0.0892 0.278 0.5556 1.1 0.925 1.31 0.0146 0.0922 0.874 0.05827 1.01 0.847 1.22 0.103 0.0922 0.262 0.5817 1.11 0.926 1.33 PRS_PLINK_0.00398107170553497 FALSE 261.41 Rickets or osteomalacia Both 14 62 3 endocrine/metabolic brown 62, 14 16, 3 15, 4 15, 2 16, 5 0.128 0.288 0.657 0.1826 1.14 0.646 2 -0.234 0.891 0.793 0.1006 0.792 0.138 4.54 -0.436 1.02 0.669 0.1747 0.646 0.0875 4.77 0.0564 0.829 0.946 0.02421 1.06 0.208 5.37 PRS_PLINK_0.00398107170553497 TRUE 262 Mineral deficiency NEC Both 231 1301 3 endocrine/metabolic brown 1301, 231 326, 50 325, 47 325, 63 325, 71 0.2 0.0745 0.00741 2.13 1.22 1.05 1.41 -0.113 0.219 0.604 0.2186 0.893 0.581 1.37 0.217 0.21 0.3 0.5227 1.24 0.824 1.87 0.399 0.208 0.0554 1.256 1.49 0.991 2.24 PRS_PLINK_0.00398107170553497 FALSE 263 Other nutritional deficiency Both 316 1700 3 endocrine/metabolic brown 1700, 316 424, 86 425, 86 425, 73 425, 71 -0.0534 0.0627 0.394 0.4047 0.948 0.838 1.07 0.0193 0.168 0.908 0.04185 1.02 0.734 1.42 -0.18 0.176 0.308 0.5109 0.836 0.591 1.18 -0.168 0.18 0.351 0.4544 0.845 0.594 1.2 PRS_PLINK_0.00398107170553497 FALSE 264 Lack of normal physiological development Both 28 177 3 endocrine/metabolic brown 177, 28 45, 9 44, 6 44, 6 44, 7 -0.109 0.188 0.563 0.2497 0.897 0.621 1.3 -0.345 0.569 0.544 0.2642 0.708 0.232 2.16 -0.464 0.611 0.448 0.3492 0.629 0.19 2.08 -0.308 0.534 0.564 0.2488 0.735 0.258 2.09 PRS_PLINK_0.00398107170553497 TRUE 264.2 Failure to thrive (childhood) Both 17 97 3 endocrine/metabolic brown 97, 17 25, 5 24, 4 24, 2 24, 6 0.108 0.252 0.669 0.1744 1.11 0.679 1.83 -0.0554 0.698 0.937 0.0284 0.946 0.241 3.71 0.441 1.09 0.687 0.1631 1.55 0.182 13.3 -0.0211 0.693 0.976 0.01068 0.979 0.252 3.81 PRS_PLINK_0.00398107170553497 TRUE 264.9 Lack of normal physiological development, unspecified Both 9 62 3 endocrine/metabolic brown 62, 9 16, 3 15, 1 15, 4 16, 1 -0.0655 0.336 0.845 0.07293 0.937 0.485 1.81 -0.0751 1.17 0.949 0.02283 0.928 0.0938 9.17 -0.0414 1.21 0.973 0.01206 0.959 0.0902 10.2 -1.07 1.14 0.35 0.4561 0.343 0.0365 3.23 PRS_PLINK_0.00398107170553497 TRUE 269 Proteinuria Both 261 1601 3 endocrine/metabolic brown 1601, 261 401, 64 400, 68 400, 66 400, 63 -0.00301 0.068 0.965 0.01559 0.997 0.873 1.14 0.108 0.189 0.566 0.2472 1.11 0.77 1.61 0.0623 0.193 0.747 0.1267 1.06 0.729 1.55 -0.00565 0.198 0.977 0.01002 0.994 0.675 1.46 PRS_PLINK_0.00398107170553497 FALSE 270 Disorders of protein plasma/amino-acid transport and metabolism Both 152 1085 3 endocrine/metabolic brown 1085, 152 272, 39 271, 44 271, 35 271, 34 -0.0735 0.0916 0.422 0.3744 0.929 0.776 1.11 0.17 0.238 0.474 0.324 1.19 0.744 1.89 -0.0928 0.253 0.714 0.1464 0.911 0.555 1.5 -0.0882 0.264 0.738 0.132 0.916 0.546 1.54 PRS_PLINK_0.00398107170553497 FALSE 270.1 Disturbances of amino-acid transport Both 23 210 3 endocrine/metabolic brown 210, 23 53, 5 52, 3 52, 6 53, 9 0.205 0.236 0.384 0.4155 1.23 0.773 1.95 -0.153 0.674 0.821 0.08575 0.858 0.229 3.22 -0.018 0.611 0.977 0.01031 0.982 0.297 3.25 0.508 0.586 0.386 0.4137 1.66 0.527 5.24 PRS_PLINK_0.00398107170553497 TRUE 270.11 Disturbances of sulphur-bearing amino-acid metabolism Both 20 178 3 endocrine/metabolic brown 178, 20 45, 4 44, 2 44, 7 45, 7 0.172 0.253 0.495 0.3051 1.19 0.724 1.95 -0.301 0.846 0.722 0.1412 0.74 0.141 3.89 0.448 0.623 0.472 0.3264 1.57 0.462 5.31 0.28 0.638 0.661 0.1795 1.32 0.378 4.62 PRS_PLINK_0.00398107170553497 TRUE 270.2 Disorders of amino-acid metabolism Both 12 122 3 endocrine/metabolic brown 122, 12 31, 2 30, 6 30, 1 31, 3 -0.156 0.291 0.591 0.2281 0.856 0.484 1.51 1.23 0.845 0.147 0.8338 3.41 0.651 17.9 -0.288 0.957 0.763 0.1173 0.75 0.115 4.89 0.579 0.874 0.508 0.2945 1.78 0.322 9.89 PRS_PLINK_0.00398107170553497 TRUE 270.3 Disorders of plasma protein metabolism Both 124 812 3 endocrine/metabolic brown 812, 124 203, 34 203, 37 203, 27 203, 26 -0.0846 0.1 0.398 0.3997 0.919 0.755 1.12 0.0926 0.256 0.717 0.1443 1.1 0.664 1.81 -0.171 0.283 0.545 0.264 0.843 0.484 1.47 -0.246 0.293 0.401 0.3973 0.782 0.44 1.39 PRS_PLINK_0.00398107170553497 FALSE 270.32 Paraproteinemia Both 65 453 3 endocrine/metabolic brown 453, 65 114, 19 113, 16 113, 16 113, 14 -0.0264 0.138 0.849 0.07121 0.974 0.743 1.28 -0.131 0.359 0.715 0.1456 0.877 0.434 1.77 -0.324 0.381 0.395 0.4038 0.723 0.342 1.53 -0.169 0.402 0.674 0.1714 0.844 0.384 1.86 PRS_PLINK_0.00398107170553497 FALSE 270.33 Amyloidosis Both 7 89 3 endocrine/metabolic brown 89, 7 23, 2 22, 3 22, 0 22, 2 0.0612 0.349 0.861 0.065 1.06 0.536 2.11 0.231 0.939 0.806 0.09378 1.26 0.2 7.93 -0.916 1.18 0.438 0.3581 0.4 0.0395 4.06 -0.206 1.05 0.845 0.0733 0.814 0.103 6.41 PRS_PLINK_0.00398107170553497 TRUE 270.34 Alpha-1-antitrypsin deficiency Both 10 79 3 endocrine/metabolic brown 79, 10 20, 1 20, 3 19, 3 20, 3 0.788 0.434 0.0693 1.159 2.2 0.94 5.15 1.06 1.41 0.453 0.3442 2.88 0.182 45.5 1.5 1.18 0.202 0.6954 4.49 0.448 45 3.54 2.06 0.0856 1.067 34.6 0.608 1960 PRS_PLINK_0.00398107170553497 TRUE 270.38 Other specified disorders of plasma protein metabolism Both 48 319 3 endocrine/metabolic brown 319, 48 80, 13 80, 12 79, 16 80, 7 -0.222 0.147 0.129 0.8886 0.801 0.601 1.07 -0.174 0.431 0.687 0.1628 0.841 0.361 1.96 0.127 0.414 0.759 0.1195 1.14 0.504 2.56 -0.543 0.488 0.266 0.575 0.581 0.223 1.51 PRS_PLINK_0.00398107170553497 TRUE 271 Disorders of carbohydrate transport and metabolism Both 638 3388 3 endocrine/metabolic brown 3388, 638 846, 131 847, 169 847, 158 847, 180 0.0818 0.0452 0.0706 1.151 1.09 0.993 1.19 0.246 0.128 0.0544 1.264 1.28 0.995 1.64 0.183 0.131 0.164 0.7855 1.2 0.928 1.55 0.361 0.13 0.00536 2.271 1.43 1.11 1.85 PRS_PLINK_0.00398107170553497 FALSE 271.3 Intestinal disaccharidase deficiencies and disaccharide malabsorption Both 627 3319 3 endocrine/metabolic brown 3319, 627 829, 131 830, 159 829, 159 830, 178 0.08 0.0456 0.0789 1.103 1.08 0.991 1.18 0.183 0.13 0.158 0.8015 1.2 0.931 1.55 0.189 0.132 0.152 0.8178 1.21 0.933 1.56 0.341 0.13 0.0087 2.061 1.41 1.09 1.82 PRS_PLINK_0.00398107170553497 FALSE 271.9 Other disorders of carbohydrate transport and metabolism Both 17 121 3 endocrine/metabolic brown 121, 17 31, 3 30, 7 30, 4 30, 3 -0.128 0.273 0.639 0.1942 0.88 0.515 1.5 0.877 0.738 0.235 0.6292 2.4 0.566 10.2 -0.144 0.819 0.861 0.06521 0.866 0.174 4.31 0.00261 0.79 0.997 0.001146 1 0.213 4.72 PRS_PLINK_0.00398107170553497 TRUE 272 Disorders of lipoid metabolism Both 2590 2592 3 endocrine/metabolic brown 2592, 2590 648, 606 648, 663 648, 659 648, 661 -0.00529 0.032 0.869 0.06112 0.995 0.934 1.06 0.0267 0.0883 0.762 0.1179 1.03 0.864 1.22 0.0266 0.0902 0.768 0.1148 1.03 0.861 1.23 0.0111 0.0927 0.905 0.04353 1.01 0.843 1.21 PRS_PLINK_0.00398107170553497 FALSE 272.1 Hyperlipidemia Both 2579 2590 3 endocrine/metabolic brown 2590, 2579 648, 602 647, 658 647, 660 648, 658 -0.00404 0.0321 0.9 0.04584 0.996 0.935 1.06 0.0271 0.0885 0.76 0.1193 1.03 0.864 1.22 0.036 0.0903 0.69 0.161 1.04 0.869 1.24 0.015 0.0928 0.872 0.05955 1.02 0.846 1.22 PRS_PLINK_0.00398107170553497 FALSE 272.11 Hypercholesterolemia Both 927 2247 3 endocrine/metabolic brown 2247, 927 562, 213 562, 228 561, 241 562, 245 0.0209 0.0445 0.638 0.1951 1.02 0.936 1.11 0.0518 0.124 0.676 0.1703 1.05 0.826 1.34 0.121 0.125 0.336 0.4734 1.13 0.882 1.44 0.0774 0.13 0.551 0.2588 1.08 0.838 1.39 PRS_PLINK_0.00398107170553497 FALSE 272.12 Hyperglyceridemia Both 116 1097 3 endocrine/metabolic brown 1097, 116 275, 31 274, 28 274, 31 274, 26 -0.0638 0.1 0.524 0.2804 0.938 0.771 1.14 -0.0125 0.274 0.964 0.01615 0.988 0.577 1.69 0.0356 0.27 0.895 0.04814 1.04 0.61 1.76 -0.0557 0.285 0.845 0.07306 0.946 0.541 1.65 PRS_PLINK_0.00398107170553497 FALSE 272.13 Mixed hyperlipidemia Both 587 1861 3 endocrine/metabolic brown 1861, 587 466, 147 465, 140 465, 149 465, 150 0.00704 0.0528 0.894 0.04868 1.01 0.908 1.12 -0.01 0.148 0.946 0.02415 0.99 0.741 1.32 0.0231 0.15 0.878 0.05674 1.02 0.763 1.37 0.0791 0.151 0.6 0.2219 1.08 0.805 1.45 PRS_PLINK_0.00398107170553497 FALSE 272.9 Unspecified disorder of lipoid metabolism Both 78 294 3 endocrine/metabolic brown 294, 78 74, 18 73, 13 73, 22 74, 25 0.0951 0.132 0.47 0.3277 1.1 0.85 1.42 -0.24 0.409 0.558 0.2537 0.787 0.353 1.75 0.259 0.376 0.49 0.3095 1.3 0.62 2.71 0.16 0.386 0.679 0.1684 1.17 0.551 2.5 PRS_PLINK_0.00398107170553497 FALSE 274 Gout and other crystal arthropathies Both 247 2143 3 endocrine/metabolic brown 2143, 247 535, 57 536, 56 535, 55 536, 79 0.0856 0.0684 0.21 0.6768 1.09 0.953 1.25 -0.0393 0.198 0.842 0.07461 0.961 0.653 1.42 -0.0126 0.202 0.95 0.02218 0.987 0.665 1.47 0.258 0.19 0.174 0.7596 1.29 0.892 1.88 PRS_PLINK_0.00398107170553497 FALSE 274.1 Gout Both 217 2031 3 endocrine/metabolic brown 2031, 217 507, 52 508, 47 507, 52 508, 66 0.0717 0.0723 0.321 0.4932 1.07 0.932 1.24 -0.117 0.21 0.577 0.2391 0.889 0.589 1.34 0.0403 0.209 0.847 0.07216 1.04 0.691 1.57 0.166 0.201 0.409 0.388 1.18 0.796 1.75 PRS_PLINK_0.00398107170553497 FALSE 274.11 Gouty arthropathy Both 134 996 3 endocrine/metabolic brown 996, 134 248, 30 249, 26 249, 34 249, 44 0.151 0.0933 0.107 0.9726 1.16 0.968 1.4 -0.0935 0.286 0.744 0.1284 0.911 0.519 1.6 0.194 0.275 0.48 0.3184 1.21 0.708 2.08 0.4 0.266 0.132 0.8778 1.49 0.886 2.51 PRS_PLINK_0.00398107170553497 FALSE 274.2 Crystal arthropathies Both 44 246 3 endocrine/metabolic brown 246, 44 61, 7 61, 11 61, 11 62, 15 0.269 0.168 0.109 0.9613 1.31 0.942 1.82 0.543 0.515 0.292 0.535 1.72 0.627 4.72 0.348 0.496 0.482 0.3167 1.42 0.536 3.74 1.01 0.519 0.0522 1.282 2.74 0.99 7.57 PRS_PLINK_0.00398107170553497 TRUE 274.21 Chondrocalcinosis Both 41 228 3 endocrine/metabolic brown 228, 41 56, 7 57, 10 57, 10 57, 14 0.239 0.171 0.163 0.7883 1.27 0.908 1.78 0.503 0.52 0.334 0.4769 1.65 0.597 4.58 0.195 0.522 0.708 0.1499 1.22 0.437 3.38 0.743 0.504 0.14 0.8537 2.1 0.784 5.64 PRS_PLINK_0.00398107170553497 TRUE 275 Disorders of mineral metabolism Both 688 3994 3 endocrine/metabolic brown 3994, 688 999, 165 998, 178 998, 187 999, 157 -0.0223 0.0427 0.603 0.22 0.978 0.899 1.06 0.0859 0.118 0.467 0.3307 1.09 0.865 1.37 0.115 0.119 0.334 0.476 1.12 0.889 1.41 0.00422 0.125 0.973 0.01186 1 0.786 1.28 PRS_PLINK_0.00398107170553497 FALSE 275.1 Disorders of iron metabolism Both 30 255 4 hematopoietic darkorange1 255, 30 64, 6 64, 5 63, 10 64, 9 0.0742 0.211 0.725 0.1396 1.08 0.712 1.63 0.0464 0.566 0.935 0.02934 1.05 0.346 3.18 0.432 0.522 0.408 0.3891 1.54 0.554 4.28 -0.153 0.6 0.799 0.09727 0.858 0.265 2.78 PRS_PLINK_0.00398107170553497 TRUE 275.11 Hereditary hemochromatosis Both 11 113 4 hematopoietic darkorange1 113, 11 29, 2 28, 4 28, 1 28, 4 -0.0573 0.348 0.869 0.0608 0.944 0.477 1.87 0.158 0.951 0.868 0.06163 1.17 0.182 7.55 -0.359 1.02 0.723 0.1406 0.698 0.0954 5.11 -0.672 1.12 0.547 0.2619 0.511 0.0573 4.55 PRS_PLINK_0.00398107170553497 TRUE 275.2 Disorders of copper metabolism Both 7 77 3 endocrine/metabolic brown 77, 7 20, 5 19, 1 19, 1 19, 0 -0.841 0.401 0.0359 1.445 0.431 0.197 0.946 -1.23 0.942 0.193 0.7141 0.294 0.0464 1.86 -1.01 0.959 0.29 0.5378 0.363 0.0554 2.37 -1.5 1.17 0.201 0.6971 0.223 0.0224 2.22 PRS_PLINK_0.00398107170553497 TRUE 275.3 Disorders of magnesium metabolism Both 138 1263 3 endocrine/metabolic brown 1263, 138 316, 33 316, 33 315, 42 316, 30 0.0116 0.0932 0.901 0.0452 1.01 0.843 1.21 0.0639 0.259 0.805 0.09412 1.07 0.641 1.77 0.245 0.25 0.327 0.4851 1.28 0.783 2.08 -0.00652 0.273 0.981 0.008353 0.994 0.582 1.7 PRS_PLINK_0.00398107170553497 FALSE 275.5 Disorders of calcium/phosphorus metabolism Both 556 3543 3 endocrine/metabolic brown 3543, 556 886, 132 886, 149 885, 141 886, 133 -0.00866 0.0473 0.855 0.06822 0.991 0.904 1.09 0.125 0.13 0.335 0.4744 1.13 0.879 1.46 0.0672 0.133 0.614 0.2118 1.07 0.824 1.39 0.0789 0.136 0.563 0.2492 1.08 0.828 1.41 PRS_PLINK_0.00398107170553497 FALSE 275.51 Hypocalcemia Both 124 957 3 endocrine/metabolic brown 957, 124 240, 20 239, 34 239, 35 239, 35 0.183 0.1 0.0665 1.177 1.2 0.988 1.46 0.591 0.293 0.0438 1.359 1.81 1.02 3.21 0.584 0.302 0.053 1.276 1.79 0.993 3.24 0.654 0.302 0.0304 1.517 1.92 1.06 3.48 PRS_PLINK_0.00398107170553497 FALSE 275.53 Disorders of phosphorus metabolism Both 168 1348 3 endocrine/metabolic brown 1348, 168 337, 40 337, 49 337, 40 337, 39 0.00851 0.0837 0.919 0.03669 1.01 0.856 1.19 0.185 0.226 0.415 0.3822 1.2 0.772 1.87 0.0224 0.241 0.926 0.03339 1.02 0.637 1.64 0.0607 0.248 0.806 0.09348 1.06 0.654 1.73 PRS_PLINK_0.00398107170553497 FALSE 275.6 Hypercalcemia Both 317 1850 3 endocrine/metabolic brown 1850, 317 463, 72 462, 75 462, 89 463, 80 0.043 0.0619 0.487 0.3122 1.04 0.925 1.18 0.0448 0.178 0.801 0.09626 1.05 0.738 1.48 0.181 0.174 0.297 0.5265 1.2 0.853 1.68 0.159 0.18 0.377 0.4233 1.17 0.824 1.67 PRS_PLINK_0.00398107170553497 FALSE 276 Disorders of fluid, electrolyte, and acid-base balance Both 1376 3779 3 endocrine/metabolic brown 3779, 1376 945, 314 945, 367 944, 345 945, 349 0.0196 0.0331 0.554 0.2565 1.02 0.956 1.09 0.144 0.0924 0.118 0.9265 1.16 0.964 1.38 0.0851 0.0948 0.369 0.4327 1.09 0.904 1.31 0.0743 0.0959 0.438 0.3582 1.08 0.893 1.3 PRS_PLINK_0.00398107170553497 FALSE 276.1 Electrolyte imbalance Both 971 3550 3 endocrine/metabolic brown 3550, 971 888, 223 887, 260 887, 247 888, 241 0.00492 0.0383 0.898 0.04674 1 0.932 1.08 0.138 0.107 0.198 0.7025 1.15 0.93 1.42 0.0866 0.109 0.428 0.369 1.09 0.881 1.35 0.0291 0.111 0.794 0.1004 1.03 0.828 1.28 PRS_PLINK_0.00398107170553497 FALSE 276.11 Hyperosmolality and/or hypernatremia Both 74 493 3 endocrine/metabolic brown 493, 74 124, 22 123, 19 123, 18 123, 15 -0.0599 0.124 0.629 0.2014 0.942 0.739 1.2 -0.0551 0.335 0.869 0.06084 0.946 0.491 1.82 -0.0844 0.349 0.809 0.09228 0.919 0.464 1.82 -0.395 0.372 0.288 0.5405 0.674 0.325 1.4 PRS_PLINK_0.00398107170553497 FALSE 276.12 Hyposmolality and/or hyponatremia Both 389 2200 3 endocrine/metabolic brown 2200, 389 550, 96 550, 100 550, 101 550, 92 -0.0176 0.0563 0.755 0.1219 0.983 0.88 1.1 0.0343 0.157 0.827 0.08227 1.03 0.76 1.41 0.0247 0.16 0.878 0.0567 1.03 0.749 1.4 -0.0757 0.163 0.643 0.1917 0.927 0.673 1.28 PRS_PLINK_0.00398107170553497 FALSE 276.13 Hyperpotassemia Both 452 2511 3 endocrine/metabolic brown 2511, 452 628, 85 628, 134 627, 117 628, 116 0.0524 0.0529 0.321 0.4928 1.05 0.95 1.17 0.428 0.152 0.00474 2.324 1.53 1.14 2.07 0.311 0.158 0.0487 1.312 1.37 1 1.86 0.227 0.161 0.157 0.8038 1.26 0.916 1.72 PRS_PLINK_0.00398107170553497 FALSE 276.14 Hypopotassemia Both 355 2305 3 endocrine/metabolic brown 2305, 355 577, 92 576, 95 576, 92 576, 76 -0.0619 0.0586 0.291 0.5358 0.94 0.838 1.05 0.0719 0.159 0.651 0.1862 1.07 0.787 1.47 0.0595 0.163 0.716 0.1452 1.06 0.771 1.46 -0.184 0.172 0.283 0.5485 0.832 0.594 1.16 PRS_PLINK_0.00398107170553497 FALSE 276.4 Acid-base balance disorder Both 283 1923 3 endocrine/metabolic brown 1923, 283 481, 89 481, 69 480, 69 481, 56 -0.152 0.0655 0.0201 1.697 0.859 0.755 0.976 -0.283 0.174 0.105 0.9788 0.754 0.536 1.06 -0.25 0.177 0.159 0.7998 0.779 0.55 1.1 -0.485 0.187 0.00944 2.025 0.615 0.427 0.888 PRS_PLINK_0.00398107170553497 FALSE 276.41 Acidosis Both 243 1699 3 endocrine/metabolic brown 1699, 243 425, 75 425, 64 424, 60 425, 44 -0.183 0.0707 0.00984 2.007 0.833 0.725 0.957 -0.182 0.185 0.326 0.4872 0.834 0.58 1.2 -0.208 0.192 0.278 0.5555 0.812 0.558 1.18 -0.504 0.209 0.0157 1.803 0.604 0.401 0.909 PRS_PLINK_0.00398107170553497 FALSE 276.42 Alkalosis Both 65 443 3 endocrine/metabolic brown 443, 65 111, 15 111, 22 110, 18 111, 10 -0.092 0.131 0.483 0.3161 0.912 0.705 1.18 0.423 0.357 0.236 0.6272 1.53 0.758 3.08 0.0123 0.373 0.974 0.01156 1.01 0.487 2.1 -0.556 0.428 0.194 0.7125 0.574 0.248 1.33 PRS_PLINK_0.00398107170553497 FALSE 276.5 Hypovolemia Both 682 3509 3 endocrine/metabolic brown 3509, 682 878, 164 877, 166 877, 172 877, 179 0.0295 0.0428 0.491 0.3089 1.03 0.947 1.12 0.0173 0.121 0.887 0.05232 1.02 0.802 1.29 0.0757 0.123 0.539 0.2688 1.08 0.847 1.37 0.116 0.123 0.343 0.4651 1.12 0.883 1.43 PRS_PLINK_0.00398107170553497 FALSE 276.6 Fluid overload Both 162 1236 3 endocrine/metabolic brown 1236, 162 309, 44 309, 49 309, 35 309, 34 -0.0787 0.0834 0.345 0.4621 0.924 0.785 1.09 0.142 0.225 0.529 0.2762 1.15 0.741 1.79 -0.215 0.246 0.384 0.4155 0.807 0.498 1.31 -0.198 0.248 0.426 0.3707 0.821 0.504 1.34 PRS_PLINK_0.00398107170553497 FALSE 276.8 Polydipsia Both 28 158 3 endocrine/metabolic brown 158, 28 40, 6 39, 7 39, 4 40, 11 -0.00543 0.209 0.979 0.009097 0.995 0.66 1.5 0.168 0.629 0.789 0.1029 1.18 0.345 4.06 -0.174 0.747 0.815 0.08867 0.84 0.194 3.63 0.529 0.557 0.342 0.4654 1.7 0.569 5.06 PRS_PLINK_0.00398107170553497 TRUE 277 Other disorders of metabolism Both 724 4055 3 endocrine/metabolic brown 4055, 724 1013, 177 1014, 186 1013, 200 1014, 161 0.0155 0.0414 0.709 0.1492 1.02 0.936 1.1 0.0626 0.115 0.586 0.2319 1.06 0.85 1.33 0.115 0.115 0.318 0.4976 1.12 0.895 1.41 -0.0676 0.122 0.578 0.2381 0.935 0.737 1.19 PRS_PLINK_0.00398107170553497 FALSE 277.2 Other disorders of purine and pyrimidine metabolism Both 52 470 3 endocrine/metabolic brown 470, 52 118, 11 117, 12 117, 15 118, 14 0.186 0.15 0.214 0.6687 1.2 0.898 1.62 0.176 0.457 0.7 0.1551 1.19 0.487 2.92 0.418 0.429 0.33 0.4815 1.52 0.655 3.52 0.386 0.433 0.372 0.4289 1.47 0.63 3.43 PRS_PLINK_0.00398107170553497 FALSE 277.4 Disorders of bilirubin excretion Both 113 701 3 endocrine/metabolic brown 701, 113 175, 28 175, 22 175, 33 175, 30 0.0994 0.105 0.342 0.4662 1.1 0.9 1.36 -0.179 0.305 0.557 0.2542 0.836 0.459 1.52 0.277 0.286 0.333 0.4782 1.32 0.753 2.31 0.0367 0.293 0.9 0.04565 1.04 0.584 1.84 PRS_PLINK_0.00398107170553497 FALSE 277.5 Other disorders of lipoid metabolism Both 158 1161 3 endocrine/metabolic brown 1161, 158 291, 40 290, 53 290, 36 290, 29 -0.107 0.0913 0.241 0.6188 0.898 0.751 1.07 0.325 0.226 0.151 0.8219 1.38 0.889 2.15 -0.0676 0.245 0.783 0.1064 0.935 0.578 1.51 -0.232 0.262 0.377 0.4242 0.793 0.475 1.33 PRS_PLINK_0.00398107170553497 FALSE 277.51 Lipoprotein disorders Both 115 949 3 endocrine/metabolic brown 949, 115 238, 29 237, 34 237, 29 237, 23 -0.00237 0.105 0.982 0.007873 0.998 0.812 1.23 0.222 0.268 0.407 0.3902 1.25 0.739 2.11 0.0613 0.282 0.828 0.08192 1.06 0.611 1.85 -0.0418 0.299 0.889 0.05115 0.959 0.533 1.72 PRS_PLINK_0.00398107170553497 FALSE 277.7 Dysmetabolic syndrome X Both 126 1203 3 endocrine/metabolic brown 1203, 126 301, 26 301, 27 300, 42 301, 31 0.0639 0.0929 0.491 0.3085 1.07 0.889 1.28 0.025 0.282 0.929 0.03177 1.03 0.589 1.78 0.427 0.269 0.112 0.9505 1.53 0.905 2.6 0.174 0.28 0.535 0.2713 1.19 0.687 2.06 PRS_PLINK_0.00398107170553497 FALSE 278 Overweight, obesity and other hyperalimentation Both 2053 3169 3 endocrine/metabolic brown 3169, 2053 792, 476 792, 521 792, 524 792, 532 0.0888 0.0296 0.00272 2.565 1.09 1.03 1.16 0.125 0.0828 0.133 0.8771 1.13 0.963 1.33 0.145 0.0839 0.0843 1.074 1.16 0.981 1.36 0.239 0.0857 0.00528 2.278 1.27 1.07 1.5 PRS_PLINK_0.00398107170553497 FALSE 278.1 Obesity Both 1508 3168 3 endocrine/metabolic brown 3168, 1508 791, 349 792, 374 792, 389 792, 396 0.107 0.0328 0.00114 2.942 1.11 1.04 1.19 0.114 0.0921 0.214 0.6699 1.12 0.936 1.34 0.161 0.0928 0.0837 1.077 1.17 0.979 1.41 0.271 0.0948 0.00426 2.371 1.31 1.09 1.58 PRS_PLINK_0.00398107170553497 FALSE 278.11 Morbid obesity Both 704 3144 3 endocrine/metabolic brown 3144, 704 785, 156 786, 169 786, 176 786, 203 0.189 0.0436 1.44e-05 4.84 1.21 1.11 1.32 0.13 0.124 0.296 0.5293 1.14 0.893 1.45 0.186 0.125 0.137 0.8629 1.2 0.942 1.54 0.442 0.125 0.000425 3.372 1.56 1.22 1.99 PRS_PLINK_0.00398107170553497 FALSE 278.3 Localized adiposity Both 58 495 3 endocrine/metabolic brown 495, 58 124, 14 124, 13 123, 17 124, 14 0.118 0.149 0.428 0.3691 1.13 0.841 1.51 0.000716 0.397 0.999 0.000626 1 0.46 2.18 0.168 0.382 0.661 0.1797 1.18 0.559 2.5 0.181 0.406 0.656 0.1834 1.2 0.541 2.66 PRS_PLINK_0.00398107170553497 FALSE 278.4 Abnormal weight gain Both 552 2521 3 endocrine/metabolic brown 2521, 552 630, 129 630, 156 630, 125 630, 142 0.0321 0.0494 0.516 0.2877 1.03 0.937 1.14 0.19 0.133 0.154 0.8114 1.21 0.931 1.57 -0.0273 0.142 0.847 0.07205 0.973 0.737 1.28 0.177 0.14 0.206 0.6869 1.19 0.907 1.57 PRS_PLINK_0.00398107170553497 FALSE 279 Disorders involving the immune mechanism Both 550 3086 3 endocrine/metabolic brown 3086, 550 772, 154 771, 140 771, 123 772, 132 -0.0568 0.0477 0.234 0.6312 0.945 0.861 1.04 -0.0879 0.128 0.493 0.3075 0.916 0.713 1.18 -0.213 0.133 0.109 0.9613 0.808 0.622 1.05 -0.184 0.134 0.168 0.7738 0.832 0.64 1.08 PRS_PLINK_0.00398107170553497 FALSE 279.1 Immunity deficiency Both 199 1250 3 endocrine/metabolic brown 1250, 199 313, 58 312, 48 312, 45 313, 48 -0.0428 0.0796 0.591 0.2282 0.958 0.82 1.12 -0.197 0.211 0.352 0.4538 0.822 0.543 1.24 -0.218 0.215 0.31 0.5092 0.804 0.527 1.23 -0.199 0.216 0.357 0.4472 0.82 0.537 1.25 PRS_PLINK_0.00398107170553497 FALSE 279.11 Deficiency of humoral immunity Both 67 397 3 endocrine/metabolic brown 397, 67 100, 19 99, 23 99, 15 99, 10 -0.154 0.13 0.236 0.6277 0.857 0.664 1.11 0.131 0.35 0.709 0.1495 1.14 0.574 2.26 -0.178 0.369 0.629 0.2012 0.837 0.406 1.72 -0.61 0.415 0.141 0.8493 0.543 0.241 1.23 PRS_PLINK_0.00398107170553497 FALSE 279.2 Autoimmune disease NEC Both 183 1031 3 endocrine/metabolic brown 1031, 183 258, 52 258, 45 257, 44 258, 41 -0.0585 0.0819 0.475 0.323 0.943 0.803 1.11 -0.138 0.222 0.534 0.2726 0.871 0.564 1.35 -0.194 0.229 0.397 0.4014 0.824 0.526 1.29 -0.211 0.234 0.367 0.4358 0.81 0.512 1.28 PRS_PLINK_0.00398107170553497 FALSE 279.7 Other immunological findings Both 976 3766 3 endocrine/metabolic brown 3766, 976 942, 253 941, 224 941, 249 942, 250 -0.0132 0.0373 0.723 0.1409 0.987 0.917 1.06 -0.127 0.105 0.226 0.6453 0.881 0.717 1.08 -0.0472 0.104 0.649 0.1874 0.954 0.778 1.17 -0.0281 0.105 0.789 0.1027 0.972 0.791 1.19 PRS_PLINK_0.00398107170553497 FALSE 279.8 Other specified disorders involving the immune mechanism Both 144 805 3 endocrine/metabolic brown 805, 144 202, 39 201, 32 201, 35 201, 37 -0.00544 0.0925 0.953 0.02087 0.995 0.83 1.19 -0.225 0.258 0.382 0.4178 0.798 0.482 1.32 -0.114 0.255 0.655 0.184 0.892 0.542 1.47 -0.0978 0.257 0.704 0.1525 0.907 0.548 1.5 PRS_PLINK_0.00398107170553497 FALSE 280 Iron deficiency anemias Both 805 3065 4 hematopoietic darkorange1 3065, 805 766, 176 766, 197 766, 218 766, 214 0.0888 0.0412 0.031 1.508 1.09 1.01 1.18 0.123 0.118 0.298 0.5256 1.13 0.897 1.42 0.227 0.118 0.0534 1.272 1.25 0.997 1.58 0.247 0.12 0.0389 1.41 1.28 1.01 1.62 PRS_PLINK_0.00398107170553497 FALSE 280.1 Iron deficiency anemias, unspecified or not due to blood loss Both 779 3057 4 hematopoietic darkorange1 3057, 779 764, 175 764, 189 764, 210 764, 205 0.0807 0.0417 0.0529 1.277 1.08 0.999 1.18 0.0898 0.119 0.45 0.347 1.09 0.867 1.38 0.196 0.118 0.097 1.013 1.22 0.965 1.53 0.215 0.121 0.0753 1.123 1.24 0.978 1.57 PRS_PLINK_0.00398107170553497 FALSE 280.2 Iron deficiency anemia secondary to blood loss (chronic) Both 269 1724 4 hematopoietic darkorange1 1724, 269 431, 64 431, 56 431, 72 431, 77 0.0957 0.0659 0.146 0.8345 1.1 0.967 1.25 -0.137 0.196 0.484 0.3154 0.872 0.594 1.28 0.165 0.188 0.379 0.4209 1.18 0.816 1.71 0.265 0.189 0.161 0.7935 1.3 0.9 1.89 PRS_PLINK_0.00398107170553497 FALSE 281 Other deficiency anemia Both 101 555 4 hematopoietic darkorange1 555, 101 139, 20 139, 23 138, 37 139, 21 -0.00678 0.116 0.953 0.02071 0.993 0.791 1.25 0.157 0.328 0.633 0.1985 1.17 0.615 2.23 0.505 0.315 0.109 0.9643 1.66 0.894 3.07 0.127 0.359 0.723 0.141 1.14 0.562 2.29 PRS_PLINK_0.00398107170553497 FALSE 281.1 Megaloblastic anemia Both 55 302 4 hematopoietic darkorange1 302, 55 76, 15 75, 10 75, 19 76, 11 -0.139 0.168 0.41 0.387 0.871 0.626 1.21 -0.428 0.433 0.323 0.4914 0.652 0.279 1.52 0.16 0.384 0.676 0.1699 1.17 0.553 2.49 -0.316 0.424 0.456 0.3409 0.729 0.317 1.67 PRS_PLINK_0.00398107170553497 FALSE 281.11 Pernicious anemia Both 24 134 4 hematopoietic darkorange1 134, 24 34, 6 33, 4 33, 9 34, 5 -0.177 0.254 0.487 0.312 0.838 0.509 1.38 -1.15 0.753 0.128 0.8918 0.318 0.0726 1.39 0.452 0.632 0.474 0.3239 1.57 0.455 5.42 -0.234 0.645 0.716 0.145 0.791 0.224 2.8 PRS_PLINK_0.00398107170553497 TRUE 281.12 Other vitamin B12 deficiency anemia Both 43 231 4 hematopoietic darkorange1 231, 43 58, 8 58, 9 57, 15 58, 11 -0.00744 0.182 0.967 0.01442 0.993 0.695 1.42 0.111 0.518 0.83 0.08082 1.12 0.405 3.08 0.466 0.462 0.313 0.504 1.59 0.644 3.94 0.329 0.478 0.491 0.309 1.39 0.545 3.55 PRS_PLINK_0.00398107170553497 TRUE 281.9 Deficiency anemias Both 52 297 4 hematopoietic darkorange1 297, 52 75, 10 74, 18 74, 16 74, 8 -0.041 0.167 0.806 0.09379 0.96 0.692 1.33 0.605 0.439 0.168 0.7751 1.83 0.775 4.33 0.561 0.449 0.211 0.675 1.75 0.727 4.22 0.275 0.588 0.64 0.194 1.32 0.416 4.17 PRS_PLINK_0.00398107170553497 FALSE 282 Hereditary hemolytic anemias Both 47 328 4 hematopoietic darkorange1 328, 47 82, 16 82, 21 82, 7 82, 3 -0.422 0.166 0.0112 1.952 0.656 0.473 0.908 0.357 0.379 0.347 0.4591 1.43 0.679 3.01 -0.909 0.493 0.065 1.187 0.403 0.153 1.06 -1.41 0.59 0.0172 1.765 0.245 0.0771 0.779 PRS_PLINK_0.00398107170553497 TRUE 282.8 Other hemoglobinopathies Both 30 229 4 hematopoietic darkorange1 229, 30 58, 8 57, 13 57, 7 57, 2 -0.228 0.212 0.28 0.5522 0.796 0.526 1.2 0.58 0.486 0.232 0.6346 1.79 0.69 4.63 -0.212 0.544 0.697 0.1566 0.809 0.279 2.35 -0.908 0.675 0.178 0.7485 0.403 0.107 1.51 PRS_PLINK_0.00398107170553497 TRUE 282.9 Other hereditary hemolytic anemias Both 28 188 4 hematopoietic darkorange1 188, 28 47, 13 47, 9 47, 4 47, 2 -0.692 0.244 0.00454 2.343 0.501 0.311 0.807 -0.377 0.503 0.454 0.3429 0.686 0.256 1.84 -1.21 0.62 0.0508 1.295 0.298 0.0884 1 -1.83 0.723 0.0113 1.947 0.16 0.0388 0.661 PRS_PLINK_0.00398107170553497 TRUE 283 Acquired hemolytic anemias Both 12 148 4 hematopoietic darkorange1 148, 12 37, 5 37, 0 37, 3 37, 4 -0.0128 0.283 0.964 0.01598 0.987 0.567 1.72 -2.79 1.31 0.033 1.481 0.0616 0.00475 0.799 -0.457 0.725 0.528 0.2771 0.633 0.153 2.62 -0.469 0.722 0.516 0.2872 0.626 0.152 2.58 PRS_PLINK_0.00398107170553497 TRUE 283.1 Autoimmune hemolytic anemias Both 6 60 4 hematopoietic darkorange1 60, 6 15, 1 15, 1 15, 2 15, 2 0.355 0.523 0.498 0.3029 1.43 0.511 3.97 0.596 1.17 0.611 0.2137 1.82 0.182 18.1 0.0977 1.23 0.937 0.0283 1.1 0.0983 12.4 0.474 1.26 0.707 0.1509 1.61 0.136 18.9 PRS_PLINK_0.00398107170553497 TRUE 284 Aplastic anemia Both 83 649 4 hematopoietic darkorange1 649, 83 163, 27 162, 20 162, 18 162, 18 -0.193 0.119 0.104 0.9816 0.825 0.653 1.04 -0.384 0.312 0.219 0.6596 0.681 0.37 1.26 -0.48 0.326 0.142 0.8492 0.619 0.327 1.17 -0.307 0.322 0.341 0.4675 0.736 0.391 1.38 PRS_PLINK_0.00398107170553497 FALSE 284.1 Pancytopenia Both 63 543 4 hematopoietic darkorange1 543, 63 136, 23 136, 10 135, 16 136, 14 -0.259 0.141 0.0667 1.176 0.772 0.585 1.02 -0.881 0.385 0.022 1.657 0.414 0.195 0.881 -0.439 0.347 0.205 0.6872 0.645 0.327 1.27 -0.431 0.354 0.223 0.6524 0.65 0.325 1.3 PRS_PLINK_0.00398107170553497 FALSE 285 Other anemias Both 1835 3213 4 hematopoietic darkorange1 3213, 1835 803, 446 803, 459 803, 479 803, 451 0.0258 0.0306 0.4 0.3982 1.03 0.966 1.09 0.0206 0.0853 0.809 0.0918 1.02 0.864 1.21 0.0737 0.086 0.391 0.4076 1.08 0.91 1.27 0.0292 0.0883 0.741 0.1303 1.03 0.866 1.22 PRS_PLINK_0.00398107170553497 FALSE 285.1 Acute posthemorrhagic anemia Both 408 2548 4 hematopoietic darkorange1 2548, 408 636, 108 637, 106 637, 101 637, 93 -0.0108 0.0549 0.844 0.07344 0.989 0.888 1.1 -0.0193 0.15 0.897 0.04703 0.981 0.731 1.32 -0.0496 0.154 0.748 0.1264 0.952 0.704 1.29 -0.122 0.158 0.439 0.3575 0.885 0.649 1.21 PRS_PLINK_0.00398107170553497 FALSE 285.2 Anemia of chronic disease Both 252 1856 4 hematopoietic darkorange1 1856, 252 464, 58 464, 62 464, 77 464, 55 -0.00756 0.0692 0.913 0.03951 0.992 0.867 1.14 0.135 0.194 0.489 0.3109 1.14 0.782 1.67 0.298 0.192 0.122 0.9138 1.35 0.924 1.96 -0.0439 0.207 0.832 0.08 0.957 0.638 1.43 PRS_PLINK_0.00398107170553497 FALSE 285.21 Anemia in chronic kidney disease Both 137 872 4 hematopoietic darkorange1 872, 137 218, 34 218, 37 218, 38 218, 28 -0.0869 0.0953 0.362 0.4416 0.917 0.761 1.1 0.187 0.26 0.472 0.3262 1.21 0.725 2 0.0637 0.268 0.812 0.0904 1.07 0.63 1.8 -0.331 0.288 0.252 0.5988 0.719 0.408 1.26 PRS_PLINK_0.00398107170553497 FALSE 285.22 Anemia in neoplastic disease Both 76 670 4 hematopoietic darkorange1 670, 76 168, 12 167, 20 167, 26 168, 18 0.192 0.123 0.117 0.932 1.21 0.953 1.54 0.504 0.369 0.172 0.765 1.65 0.804 3.41 0.783 0.367 0.0328 1.485 2.19 1.07 4.49 0.599 0.39 0.125 0.9032 1.82 0.847 3.91 PRS_PLINK_0.00398107170553497 FALSE 286 Coagulation defects Both 480 3692 4 hematopoietic darkorange1 3692, 480 922, 113 923, 117 923, 120 923, 130 0.0276 0.0498 0.579 0.2373 1.03 0.932 1.13 0.0432 0.14 0.758 0.1203 1.04 0.793 1.37 0.0059 0.142 0.967 0.01465 1.01 0.762 1.33 0.161 0.141 0.254 0.5951 1.17 0.891 1.55 PRS_PLINK_0.00398107170553497 FALSE 286.1 Congenital coagulation defects Both 34 282 4 hematopoietic darkorange1 282, 34 71, 5 70, 10 70, 7 71, 12 0.367 0.187 0.0504 1.298 1.44 0.999 2.08 0.867 0.551 0.116 0.9358 2.38 0.807 7.01 0.395 0.571 0.49 0.3101 1.48 0.484 4.55 0.787 0.556 0.157 0.8037 2.2 0.738 6.53 PRS_PLINK_0.00398107170553497 TRUE 286.11 Von willebrand's disease Both 11 97 4 hematopoietic darkorange1 97, 11 25, 0 24, 3 24, 3 24, 5 0.724 0.382 0.0582 1.235 2.06 0.975 4.36 1.38 1.17 0.237 0.6256 3.98 0.403 39.3 1.5 1.1 0.171 0.7663 4.49 0.522 38.5 2.21 1.14 0.0527 1.278 9.12 0.974 85.3 PRS_PLINK_0.00398107170553497 TRUE 286.12 Congenital deficiency of other clotting factors (including factor VII) Both 17 156 4 hematopoietic darkorange1 156, 17 39, 4 39, 7 39, 2 39, 4 0.0313 0.248 0.9 0.04599 1.03 0.634 1.68 0.598 0.637 0.347 0.4593 1.82 0.522 6.34 -0.745 0.745 0.317 0.4988 0.475 0.11 2.04 -0.185 0.713 0.795 0.09939 0.831 0.205 3.36 PRS_PLINK_0.00398107170553497 TRUE 286.2 Encounter for long-term (current) use of anticoagulants Both 394 2625 4 hematopoietic darkorange1 2625, 394 656, 85 656, 93 656, 115 656, 101 0.0381 0.0563 0.499 0.3016 1.04 0.93 1.16 0.0584 0.163 0.72 0.1428 1.06 0.77 1.46 0.236 0.158 0.135 0.8699 1.27 0.929 1.73 0.113 0.166 0.494 0.3059 1.12 0.809 1.55 PRS_PLINK_0.00398107170553497 FALSE 286.3 Coagulation defects complicating pregnancy or postpartum Female 23 131 4 hematopoietic darkorange1 131, 23 33, 9 33, 2 32, 8 33, 4 -0.223 0.261 0.394 0.404 0.8 0.479 1.34 -1.34 0.769 0.0814 1.09 0.262 0.0581 1.18 -0.00526 0.612 0.993 0.002992 0.995 0.3 3.3 -1.26 0.82 0.125 0.9022 0.285 0.057 1.42 PRS_PLINK_0.00398107170553497 TRUE 286.4 Acquired coagulation factor deficiency Both 19 219 4 hematopoietic darkorange1 219, 19 55, 8 55, 4 54, 3 55, 4 -0.552 0.235 0.0188 1.727 0.576 0.363 0.912 -0.562 0.594 0.344 0.4633 0.57 0.178 1.83 -0.982 0.655 0.134 0.8738 0.374 0.104 1.35 -0.661 0.613 0.282 0.5505 0.517 0.155 1.72 PRS_PLINK_0.00398107170553497 TRUE 286.5 Hemorrhagic disorder due to intrinsic circulating anticoagulants Both 11 119 4 hematopoietic darkorange1 119, 11 30, 3 30, 2 29, 1 30, 5 0.224 0.324 0.491 0.309 1.25 0.662 2.36 -0.154 0.883 0.862 0.06463 0.857 0.152 4.84 -0.464 0.964 0.63 0.2006 0.629 0.0951 4.16 1.34 0.908 0.141 0.8512 3.81 0.642 22.6 PRS_PLINK_0.00398107170553497 TRUE 286.6 Defibrination syndrome Both 317 2813 4 hematopoietic darkorange1 2813, 317 703, 79 703, 72 703, 80 703, 86 0.00421 0.0601 0.944 0.02498 1 0.893 1.13 -0.0928 0.171 0.588 0.2305 0.911 0.651 1.28 -0.0658 0.17 0.699 0.1557 0.936 0.671 1.31 0.0784 0.17 0.644 0.1908 1.08 0.775 1.51 PRS_PLINK_0.00398107170553497 FALSE 286.7 Other and unspecified coagulation defects Both 374 3251 4 hematopoietic darkorange1 3251, 374 812, 90 813, 90 812, 91 813, 103 0.0091 0.0556 0.87 0.06051 1.01 0.905 1.13 0.000281 0.157 0.999 0.0006216 1 0.735 1.36 -0.0537 0.159 0.735 0.1336 0.948 0.694 1.29 0.106 0.157 0.5 0.3007 1.11 0.817 1.51 PRS_PLINK_0.00398107170553497 FALSE 286.8 Hypercoagulable state Both 109 1026 4 hematopoietic darkorange1 1026, 109 257, 30 256, 19 256, 28 257, 32 0.0129 0.102 0.899 0.04625 1.01 0.83 1.24 -0.32 0.3 0.287 0.5424 0.726 0.403 1.31 -0.0558 0.284 0.844 0.07351 0.946 0.542 1.65 0.0992 0.283 0.726 0.1391 1.1 0.634 1.92 PRS_PLINK_0.00398107170553497 FALSE 286.81 Primary hypercoagulable state Both 105 979 4 hematopoietic darkorange1 979, 105 245, 31 245, 19 244, 25 245, 30 -0.0194 0.104 0.852 0.06931 0.981 0.799 1.2 -0.413 0.3 0.168 0.775 0.662 0.368 1.19 -0.193 0.29 0.506 0.296 0.825 0.467 1.45 0.0559 0.282 0.843 0.07426 1.06 0.608 1.84 PRS_PLINK_0.00398107170553497 FALSE 286.9 Abnormal coagulation profile Both 136 1199 4 hematopoietic darkorange1 1199, 136 300, 32 300, 32 299, 36 300, 36 0.112 0.0939 0.235 0.6287 1.12 0.93 1.34 0.0782 0.262 0.765 0.1164 1.08 0.648 1.81 0.137 0.262 0.603 0.22 1.15 0.686 1.92 0.397 0.272 0.144 0.8412 1.49 0.873 2.53 PRS_PLINK_0.00398107170553497 FALSE 287 Purpura and other hemorrhagic conditions Both 420 2970 4 hematopoietic darkorange1 2970, 420 742, 103 742, 123 742, 108 743, 86 -0.111 0.0541 0.0397 1.401 0.895 0.805 0.995 0.144 0.144 0.318 0.4981 1.16 0.871 1.53 -0.0654 0.15 0.664 0.1779 0.937 0.698 1.26 -0.316 0.162 0.0511 1.291 0.729 0.531 1 PRS_PLINK_0.00398107170553497 FALSE 287.1 Spontaneous ecchymoses Both 55 240 4 hematopoietic darkorange1 240, 55 60, 9 60, 13 60, 13 60, 20 0.356 0.162 0.0281 1.552 1.43 1.04 1.96 0.509 0.478 0.287 0.5418 1.66 0.652 4.25 0.363 0.477 0.447 0.3501 1.44 0.565 3.66 0.708 0.451 0.116 0.9348 2.03 0.839 4.91 PRS_PLINK_0.00398107170553497 FALSE 287.3 Thrombocytopenia Both 365 2645 4 hematopoietic darkorange1 2645, 365 661, 90 661, 105 661, 95 661, 75 -0.0954 0.0582 0.101 0.9944 0.909 0.811 1.02 0.124 0.154 0.423 0.3735 1.13 0.836 1.53 -0.0376 0.16 0.814 0.08924 0.963 0.704 1.32 -0.28 0.172 0.104 0.9836 0.756 0.539 1.06 PRS_PLINK_0.00398107170553497 FALSE 287.31 Primary thrombocytopenia Both 67 615 4 hematopoietic darkorange1 615, 67 154, 18 154, 18 153, 18 154, 13 -0.161 0.13 0.216 0.6663 0.851 0.66 1.1 -0.03 0.346 0.931 0.03116 0.97 0.493 1.91 -0.112 0.347 0.747 0.1268 0.894 0.453 1.77 -0.35 0.375 0.351 0.4542 0.705 0.338 1.47 PRS_PLINK_0.00398107170553497 FALSE 287.32 Secondary thrombocytopenia Both 62 541 4 hematopoietic darkorange1 541, 62 136, 13 135, 23 135, 19 135, 7 -0.133 0.139 0.339 0.4699 0.876 0.667 1.15 0.562 0.356 0.115 0.9403 1.75 0.873 3.52 0.285 0.372 0.443 0.354 1.33 0.642 2.76 -0.444 0.478 0.353 0.4522 0.642 0.251 1.64 PRS_PLINK_0.00398107170553497 FALSE 287.4 Qualitative platelet defects Both 12 139 4 hematopoietic darkorange1 139, 12 35, 4 35, 2 34, 4 35, 2 -0.34 0.301 0.258 0.5879 0.712 0.395 1.28 -0.9 0.791 0.255 0.5928 0.407 0.0863 1.92 0.0851 0.763 0.911 0.0404 1.09 0.244 4.86 -0.0595 0.774 0.939 0.02747 0.942 0.207 4.3 PRS_PLINK_0.00398107170553497 TRUE 288 Diseases of white blood cells Both 724 3705 4 hematopoietic darkorange1 3705, 724 926, 175 926, 161 926, 197 926, 191 0.0418 0.0417 0.316 0.5001 1.04 0.961 1.13 -0.091 0.12 0.448 0.3489 0.913 0.722 1.15 0.0796 0.117 0.495 0.3053 1.08 0.862 1.36 0.0739 0.119 0.535 0.2714 1.08 0.852 1.36 PRS_PLINK_0.00398107170553497 FALSE 288.1 Decreased white blood cell count Both 294 1739 4 hematopoietic darkorange1 1739, 294 435, 69 435, 72 434, 75 435, 78 0.0333 0.0655 0.612 0.2133 1.03 0.909 1.18 0.0904 0.182 0.62 0.2076 1.09 0.766 1.56 0.0869 0.184 0.637 0.1961 1.09 0.761 1.56 0.212 0.185 0.253 0.5977 1.24 0.86 1.78 PRS_PLINK_0.00398107170553497 FALSE 288.11 Neutropenia Both 160 1173 4 hematopoietic darkorange1 1173, 160 294, 43 293, 38 293, 42 293, 37 -0.0153 0.0878 0.861 0.06485 0.985 0.829 1.17 -0.0382 0.236 0.872 0.05964 0.963 0.606 1.53 0.0139 0.234 0.953 0.02107 1.01 0.642 1.6 -0.0419 0.246 0.865 0.06291 0.959 0.592 1.55 PRS_PLINK_0.00398107170553497 FALSE 288.2 Elevated white blood cell count Both 599 3578 4 hematopoietic darkorange1 3578, 599 894, 152 894, 126 894, 165 895, 156 0.0297 0.0451 0.51 0.292 1.03 0.943 1.13 -0.203 0.13 0.12 0.9193 0.817 0.632 1.05 0.0488 0.125 0.696 0.1577 1.05 0.822 1.34 0.00053 0.128 0.997 0.001437 1 0.778 1.29 PRS_PLINK_0.00398107170553497 FALSE 288.3 Eosinophilia Both 33 202 4 hematopoietic darkorange1 202, 33 51, 10 50, 5 50, 9 51, 9 0.0332 0.208 0.873 0.05892 1.03 0.688 1.55 -0.938 0.586 0.109 0.9614 0.391 0.124 1.23 -0.347 0.528 0.511 0.2918 0.707 0.251 1.99 0.0414 0.537 0.938 0.02757 1.04 0.364 2.99 PRS_PLINK_0.00398107170553497 TRUE 289 Other diseases of blood and blood-forming organs Both 348 2027 4 hematopoietic darkorange1 2027, 348 507, 72 507, 82 506, 102 507, 92 0.118 0.0604 0.0509 1.293 1.13 1 1.27 0.148 0.174 0.394 0.4044 1.16 0.825 1.63 0.393 0.169 0.0203 1.693 1.48 1.06 2.06 0.271 0.175 0.122 0.9129 1.31 0.93 1.85 PRS_PLINK_0.00398107170553497 FALSE 289.3 Personal history of diseases of blood and blood-forming organs Both 197 1176 4 hematopoietic darkorange1 1176, 197 294, 43 294, 39 294, 52 294, 63 0.173 0.0797 0.0299 1.525 1.19 1.02 1.39 -0.086 0.236 0.716 0.1451 0.918 0.577 1.46 0.22 0.225 0.327 0.4854 1.25 0.802 1.94 0.345 0.22 0.117 0.9337 1.41 0.918 2.17 PRS_PLINK_0.00398107170553497 FALSE 289.4 Lymphadenitis Both 602 3530 4 hematopoietic darkorange1 3530, 602 882, 144 882, 159 882, 161 883, 138 -0.029 0.0451 0.52 0.2843 0.971 0.889 1.06 0.116 0.125 0.355 0.4492 1.12 0.878 1.44 0.123 0.127 0.332 0.4787 1.13 0.882 1.45 -0.0447 0.133 0.737 0.1326 0.956 0.737 1.24 PRS_PLINK_0.00398107170553497 FALSE 289.5 Diseases of spleen Both 51 365 4 hematopoietic darkorange1 365, 51 92, 9 91, 7 91, 21 91, 14 0.139 0.153 0.365 0.438 1.15 0.851 1.55 0.112 0.513 0.826 0.08281 1.12 0.41 3.06 0.77 0.424 0.0692 1.16 2.16 0.941 4.96 0.546 0.448 0.224 0.6507 1.73 0.717 4.16 PRS_PLINK_0.00398107170553497 FALSE 289.8 Polycythemia, secondary Both 29 195 4 hematopoietic darkorange1 195, 29 49, 4 49, 6 48, 12 49, 7 0.21 0.223 0.347 0.4602 1.23 0.797 1.91 0.272 0.605 0.653 0.185 1.31 0.401 4.29 1.29 0.622 0.0381 1.419 3.64 1.07 12.3 0.509 0.649 0.433 0.3632 1.66 0.466 5.94 PRS_PLINK_0.00398107170553497 TRUE 289.9 Abnormality of red blood cells Both 78 439 4 hematopoietic darkorange1 439, 78 110, 17 110, 19 109, 21 110, 21 0.0869 0.134 0.517 0.2868 1.09 0.839 1.42 0.248 0.378 0.513 0.2899 1.28 0.61 2.69 0.266 0.359 0.459 0.3385 1.3 0.646 2.64 0.304 0.379 0.422 0.3743 1.36 0.645 2.85 PRS_PLINK_0.00398107170553497 FALSE 290 Delirium dementia and amnestic and other cognitive disorders Both 202 1066 5 mental disorders magenta 1066, 202 267, 42 266, 63 266, 50 267, 46 -0.021 0.0803 0.794 0.1002 0.979 0.837 1.15 0.335 0.221 0.13 0.8862 1.4 0.906 2.16 0.19 0.233 0.415 0.3824 1.21 0.766 1.91 0.0597 0.247 0.809 0.09189 1.06 0.654 1.72 PRS_PLINK_0.00398107170553497 FALSE 290.1 Dementias Both 99 430 5 mental disorders magenta 430, 99 108, 23 107, 28 107, 22 108, 26 -0.00472 0.115 0.967 0.01444 0.995 0.794 1.25 0.185 0.332 0.577 0.2391 1.2 0.628 2.31 -0.0862 0.347 0.804 0.09488 0.917 0.465 1.81 0.226 0.345 0.512 0.2905 1.25 0.637 2.47 PRS_PLINK_0.00398107170553497 FALSE 290.11 Alzheimer's disease Both 34 147 5 mental disorders magenta 147, 34 37, 11 37, 9 36, 5 37, 9 -0.134 0.196 0.494 0.3063 0.874 0.595 1.28 -0.324 0.522 0.534 0.2722 0.723 0.26 2.01 -0.604 0.64 0.346 0.4614 0.547 0.156 1.92 0.29 0.574 0.614 0.212 1.34 0.434 4.12 PRS_PLINK_0.00398107170553497 TRUE 290.12 Dementia with cerebral degenerations Both 15 79 5 mental disorders magenta 79, 15 20, 1 20, 5 19, 2 20, 7 0.49 0.268 0.0674 1.172 1.63 0.966 2.76 1.88 1.2 0.115 0.9376 6.58 0.63 68.7 0.291 1.22 0.811 0.09072 1.34 0.123 14.6 1.45 0.886 0.101 0.9936 4.26 0.752 24.2 PRS_PLINK_0.00398107170553497 TRUE 290.13 Senile dementia Both 68 271 5 mental disorders magenta 271, 68 68, 20 68, 16 67, 21 68, 11 -0.104 0.135 0.443 0.3536 0.902 0.692 1.17 -0.0889 0.409 0.828 0.08208 0.915 0.411 2.04 0.163 0.383 0.67 0.174 1.18 0.556 2.49 -0.426 0.442 0.335 0.475 0.653 0.274 1.55 PRS_PLINK_0.00398107170553497 FALSE 290.16 Vascular dementia Both 14 66 5 mental disorders magenta 66, 14 17, 3 16, 3 16, 4 17, 4 -0.0874 0.331 0.792 0.1013 0.916 0.479 1.75 -0.0322 0.933 0.972 0.01212 0.968 0.156 6.03 0.0172 0.908 0.985 0.006622 1.02 0.172 6.03 -0.543 0.978 0.579 0.2376 0.581 0.0855 3.95 PRS_PLINK_0.00398107170553497 TRUE 290.2 Delirium due to conditions classified elsewhere Both 99 637 5 mental disorders magenta 637, 99 160, 19 159, 34 159, 21 159, 24 -0.0555 0.109 0.61 0.215 0.946 0.764 1.17 0.538 0.308 0.081 1.092 1.71 0.936 3.13 0.125 0.344 0.717 0.1446 1.13 0.578 2.22 0.275 0.338 0.417 0.3803 1.32 0.678 2.55 PRS_PLINK_0.00398107170553497 FALSE 290.3 Other persistent mental disorders due to conditions classified elsewhere Both 162 870 5 mental disorders magenta 870, 162 218, 37 217, 42 217, 37 218, 46 0.0629 0.0876 0.473 0.3252 1.06 0.897 1.26 0.168 0.247 0.497 0.3041 1.18 0.729 1.92 -0.0448 0.258 0.862 0.06435 0.956 0.576 1.59 0.259 0.255 0.309 0.5095 1.3 0.786 2.14 PRS_PLINK_0.00398107170553497 FALSE 291 Other specified nonpsychotic and/or transient mental disorders Both 436 2666 5 mental disorders magenta 2666, 436 667, 108 666, 110 666, 117 667, 101 0.0188 0.0537 0.727 0.1384 1.02 0.917 1.13 0.00871 0.147 0.953 0.02107 1.01 0.757 1.34 0.0889 0.147 0.545 0.2639 1.09 0.82 1.46 -0.105 0.154 0.493 0.3074 0.9 0.666 1.22 PRS_PLINK_0.00398107170553497 FALSE 291.1 Transient mental disorders due to conditions classified elsewhere Both 40 251 5 mental disorders magenta 251, 40 63, 10 63, 10 62, 11 63, 9 -0.0108 0.175 0.951 0.02181 0.989 0.702 1.39 0.156 0.479 0.745 0.1281 1.17 0.457 2.99 0.198 0.499 0.692 0.16 1.22 0.459 3.24 -0.165 0.505 0.745 0.1281 0.848 0.315 2.28 PRS_PLINK_0.00398107170553497 TRUE 291.4 Specific nonpsychotic mental disorders due to brain damage Both 82 537 5 mental disorders magenta 537, 82 135, 19 134, 20 134, 26 134, 17 0.0138 0.12 0.909 0.04146 1.01 0.801 1.28 0.0108 0.338 0.975 0.01119 1.01 0.522 1.96 0.253 0.323 0.432 0.364 1.29 0.685 2.42 -0.13 0.366 0.722 0.1414 0.878 0.429 1.8 PRS_PLINK_0.00398107170553497 FALSE 291.8 Alteration of consciousness Both 340 2112 5 mental disorders magenta 2112, 340 528, 81 528, 90 528, 89 528, 80 0.0338 0.0607 0.578 0.2382 1.03 0.918 1.16 0.101 0.166 0.542 0.2658 1.11 0.799 1.53 0.0635 0.168 0.705 0.1516 1.07 0.767 1.48 -0.0625 0.174 0.719 0.1434 0.939 0.669 1.32 PRS_PLINK_0.00398107170553497 FALSE 292 Neurological disorders Both 884 3965 5 mental disorders magenta 3965, 884 992, 205 991, 220 991, 223 991, 235 0.0651 0.0389 0.0943 1.026 1.07 0.989 1.15 0.0462 0.109 0.673 0.1718 1.05 0.845 1.3 0.0928 0.111 0.404 0.3939 1.1 0.882 1.36 0.123 0.111 0.27 0.569 1.13 0.909 1.41 PRS_PLINK_0.00398107170553497 FALSE 292.1 Aphasia/speech disturbance Both 254 1927 5 mental disorders magenta 1927, 254 482, 60 482, 70 481, 69 482, 55 -0.0292 0.0683 0.669 0.1746 0.971 0.849 1.11 0.135 0.187 0.47 0.3276 1.14 0.793 1.65 0.123 0.191 0.518 0.2855 1.13 0.778 1.64 -0.219 0.205 0.285 0.5447 0.804 0.538 1.2 PRS_PLINK_0.00398107170553497 FALSE 292.11 Aphasia Both 94 648 5 mental disorders magenta 648, 94 162, 20 162, 29 162, 23 162, 22 -0.0493 0.11 0.654 0.1846 0.952 0.767 1.18 0.372 0.306 0.225 0.6478 1.45 0.796 2.64 0.0599 0.325 0.854 0.06871 1.06 0.562 2.01 -0.0618 0.334 0.853 0.069 0.94 0.489 1.81 PRS_PLINK_0.00398107170553497 FALSE 292.12 Symbolic dysfunction Both 24 165 5 mental disorders magenta 165, 24 42, 4 41, 10 41, 2 41, 8 0.17 0.21 0.417 0.3796 1.19 0.786 1.79 0.832 0.61 0.172 0.7633 2.3 0.695 7.59 -0.348 0.785 0.658 0.182 0.706 0.152 3.29 0.475 0.65 0.465 0.3322 1.61 0.449 5.75 PRS_PLINK_0.00398107170553497 TRUE 292.2 Mild cognitive impairment Both 78 362 5 mental disorders magenta 362, 78 91, 18 90, 17 90, 18 91, 25 0.198 0.13 0.128 0.8924 1.22 0.945 1.57 0.123 0.377 0.744 0.1287 1.13 0.54 2.37 0.093 0.381 0.807 0.09298 1.1 0.52 2.32 0.484 0.37 0.192 0.7177 1.62 0.785 3.35 PRS_PLINK_0.00398107170553497 FALSE 292.3 Memory loss Both 396 1993 5 mental disorders magenta 1993, 396 499, 91 498, 95 498, 89 498, 121 0.0881 0.0576 0.126 0.9005 1.09 0.976 1.22 0.0531 0.162 0.744 0.1285 1.05 0.767 1.45 -0.0758 0.167 0.65 0.1873 0.927 0.668 1.29 0.281 0.16 0.0798 1.098 1.32 0.967 1.81 PRS_PLINK_0.00398107170553497 FALSE 292.4 Altered mental status Both 336 2227 5 mental disorders magenta 2227, 336 557, 95 557, 89 556, 77 557, 74 -0.0733 0.0602 0.224 0.6499 0.929 0.826 1.05 -0.0693 0.161 0.666 0.1765 0.933 0.681 1.28 -0.203 0.168 0.228 0.6415 0.816 0.587 1.14 -0.26 0.172 0.13 0.8869 0.771 0.551 1.08 PRS_PLINK_0.00398107170553497 FALSE 292.5 Transient alteration of awareness Both 76 461 5 mental disorders magenta 461, 76 116, 15 115, 21 115, 25 115, 15 0.0543 0.133 0.683 0.1653 1.06 0.813 1.37 0.402 0.361 0.265 0.5771 1.5 0.737 3.03 0.565 0.357 0.114 0.9449 1.76 0.874 3.54 -0.117 0.388 0.763 0.1174 0.89 0.416 1.9 PRS_PLINK_0.00398107170553497 FALSE 292.6 Hallucinations Both 38 227 5 mental disorders magenta 227, 38 57, 8 57, 8 56, 8 57, 14 0.143 0.174 0.411 0.3866 1.15 0.821 1.62 0.0244 0.534 0.964 0.01613 1.02 0.36 2.92 0.346 0.578 0.549 0.2602 1.41 0.455 4.39 0.549 0.482 0.254 0.5949 1.73 0.674 4.45 PRS_PLINK_0.00398107170553497 TRUE 293 Symptoms involving head and neck Both 100 512 5 mental disorders magenta 512, 100 128, 24 128, 22 128, 30 128, 24 0.0378 0.115 0.742 0.1295 1.04 0.829 1.3 -0.0843 0.321 0.793 0.1008 0.919 0.49 1.72 0.27 0.311 0.387 0.4127 1.31 0.711 2.41 0.125 0.332 0.706 0.1514 1.13 0.591 2.17 PRS_PLINK_0.00398107170553497 FALSE 293.1 Swelling, mass, or lump in head and neck [Space-occupying lesion, intracranial NOS] Both 618 4208 5 mental disorders magenta 4208, 618 1051, 153 1052, 174 1052, 167 1052, 124 -0.0619 0.0444 0.163 0.7869 0.94 0.862 1.03 0.157 0.12 0.191 0.7197 1.17 0.925 1.48 0.114 0.123 0.352 0.4532 1.12 0.881 1.43 -0.201 0.133 0.132 0.8798 0.818 0.63 1.06 PRS_PLINK_0.00398107170553497 FALSE 295 Schizophrenia and other psychotic disorders Both 171 602 5 mental disorders magenta 602, 171 151, 38 150, 47 150, 51 151, 34 0.014 0.0915 0.879 0.05614 1.01 0.848 1.21 0.24 0.251 0.339 0.4693 1.27 0.777 2.08 0.292 0.254 0.25 0.6026 1.34 0.814 2.2 -0.045 0.269 0.867 0.06205 0.956 0.565 1.62 PRS_PLINK_0.00398107170553497 FALSE 295.1 Schizophrenia Both 23 97 5 mental disorders magenta 97, 23 25, 1 24, 10 24, 7 24, 5 0.184 0.227 0.419 0.378 1.2 0.77 1.88 1.91 0.86 0.0263 1.58 6.76 1.25 36.5 1.53 0.892 0.0875 1.058 4.6 0.799 26.4 1.03 0.884 0.242 0.6154 2.81 0.497 15.9 PRS_PLINK_0.00398107170553497 TRUE 295.2 Paranoid disorders Both 18 70 5 mental disorders magenta 70, 18 18, 1 17, 3 17, 9 18, 5 0.422 0.316 0.183 0.7386 1.52 0.82 2.83 0.415 1.36 0.759 0.1195 1.51 0.106 21.6 2.13 1.13 0.0606 1.218 8.4 0.91 77.5 1.47 1 0.14 0.853 4.37 0.616 31 PRS_PLINK_0.00398107170553497 TRUE 295.3 Psychosis Both 153 490 5 mental disorders magenta 490, 153 123, 38 122, 42 122, 43 123, 29 -0.0952 0.1 0.342 0.4654 0.909 0.747 1.11 0.0875 0.261 0.738 0.1321 1.09 0.654 1.82 0.0745 0.27 0.782 0.1066 1.08 0.635 1.83 -0.253 0.284 0.373 0.4287 0.776 0.445 1.35 PRS_PLINK_0.00398107170553497 FALSE 296 Mood disorders Both 2307 1405 5 mental disorders magenta 1405, 2307 352, 569 351, 622 351, 557 351, 558 0.0422 0.0354 0.234 0.6306 1.04 0.973 1.12 0.142 0.0988 0.15 0.8225 1.15 0.95 1.4 0.0508 0.101 0.616 0.2105 1.05 0.863 1.28 0.0383 0.102 0.706 0.151 1.04 0.851 1.27 PRS_PLINK_0.00398107170553497 FALSE 296.1 Bipolar Both 222 891 5 mental disorders magenta 891, 222 223, 55 223, 64 222, 55 223, 48 0.00995 0.0769 0.897 0.04717 1.01 0.869 1.17 0.0686 0.212 0.746 0.1271 1.07 0.707 1.62 -0.089 0.221 0.687 0.1628 0.915 0.593 1.41 -0.0977 0.223 0.662 0.1793 0.907 0.585 1.4 PRS_PLINK_0.00398107170553497 FALSE 296.2 Depression Both 2240 1401 5 mental disorders magenta 1401, 2240 351, 552 350, 606 350, 537 350, 544 0.0457 0.0357 0.201 0.6965 1.05 0.976 1.12 0.152 0.0996 0.127 0.8961 1.16 0.958 1.42 0.05 0.102 0.625 0.2043 1.05 0.86 1.28 0.0459 0.102 0.654 0.1842 1.05 0.857 1.28 PRS_PLINK_0.00398107170553497 FALSE 296.22 Major depressive disorder Both 2061 1403 5 mental disorders magenta 1403, 2061 351, 508 351, 554 350, 497 351, 501 0.0514 0.0364 0.157 0.8028 1.05 0.98 1.13 0.144 0.102 0.156 0.8082 1.16 0.947 1.41 0.06 0.104 0.564 0.2486 1.06 0.866 1.3 0.0507 0.104 0.627 0.2028 1.05 0.858 1.29 PRS_PLINK_0.00398107170553497 FALSE 297 Suicidal ideation or attempt Both 155 649 5 mental disorders magenta 649, 155 163, 34 162, 48 162, 38 162, 35 0.00787 0.09 0.93 0.0314 1.01 0.845 1.2 0.473 0.263 0.0719 1.144 1.61 0.959 2.69 0.103 0.28 0.712 0.1476 1.11 0.64 1.92 0.209 0.281 0.457 0.3398 1.23 0.711 2.14 PRS_PLINK_0.00398107170553497 FALSE 297.1 Suicidal ideation Both 116 538 5 mental disorders magenta 538, 116 135, 23 134, 39 134, 31 135, 23 -0.0329 0.103 0.75 0.1248 0.968 0.79 1.18 0.512 0.294 0.0819 1.087 1.67 0.937 2.97 0.13 0.32 0.684 0.1651 1.14 0.609 2.13 0.0103 0.325 0.975 0.01111 1.01 0.535 1.91 PRS_PLINK_0.00398107170553497 FALSE 297.2 Suicide or self-inflicted injury Both 59 190 5 mental disorders magenta 190, 59 48, 14 47, 16 47, 16 48, 13 0.0887 0.161 0.581 0.2357 1.09 0.797 1.5 0.38 0.453 0.403 0.3951 1.46 0.601 3.56 0.193 0.475 0.684 0.1648 1.21 0.478 3.08 0.0712 0.466 0.878 0.0563 1.07 0.431 2.67 PRS_PLINK_0.00398107170553497 FALSE 300 Anxiety disorders Both 2425 1402 5 mental disorders magenta 1402, 2425 351, 604 350, 633 350, 586 351, 601 0.0546 0.0351 0.12 0.9203 1.06 0.986 1.13 0.0997 0.0982 0.31 0.5083 1.1 0.911 1.34 0.0346 0.1 0.731 0.1362 1.04 0.85 1.26 0.0822 0.1 0.412 0.3852 1.09 0.892 1.32 PRS_PLINK_0.00398107170553497 FALSE 300.1 Anxiety disorder Both 2264 1403 5 mental disorders magenta 1403, 2264 351, 567 351, 589 350, 546 351, 561 0.0612 0.0357 0.0865 1.063 1.06 0.991 1.14 0.0962 0.0998 0.335 0.475 1.1 0.905 1.34 0.0322 0.102 0.753 0.1234 1.03 0.845 1.26 0.0883 0.102 0.385 0.414 1.09 0.895 1.33 PRS_PLINK_0.00398107170553497 FALSE 300.11 Generalized anxiety disorder Both 1052 1391 5 mental disorders magenta 1391, 1052 348, 260 348, 271 347, 256 348, 264 0.0474 0.0434 0.275 0.5605 1.05 0.963 1.14 0.0642 0.12 0.594 0.2262 1.07 0.842 1.35 0.0115 0.124 0.926 0.03339 1.01 0.794 1.29 0.0568 0.122 0.642 0.1926 1.06 0.833 1.34 PRS_PLINK_0.00398107170553497 FALSE 300.12 Agorophobia, social phobia, and panic disorder Both 272 925 5 mental disorders magenta 925, 272 232, 64 231, 61 231, 72 231, 75 0.116 0.0722 0.107 0.9712 1.12 0.975 1.29 -0.0906 0.21 0.667 0.1761 0.913 0.605 1.38 0.0762 0.204 0.709 0.1495 1.08 0.723 1.61 0.17 0.207 0.411 0.3866 1.19 0.791 1.78 PRS_PLINK_0.00398107170553497 FALSE 300.13 Phobia Both 206 789 5 mental disorders magenta 789, 206 198, 49 197, 61 197, 55 197, 41 0.0103 0.0835 0.901 0.04506 1.01 0.858 1.19 0.195 0.223 0.382 0.4181 1.22 0.785 1.88 -0.0245 0.23 0.915 0.03851 0.976 0.622 1.53 -0.217 0.248 0.381 0.4195 0.805 0.495 1.31 PRS_PLINK_0.00398107170553497 FALSE 300.3 Obsessive-compulsive disorders Both 74 268 5 mental disorders magenta 268, 74 67, 13 67, 24 67, 20 67, 17 0.134 0.131 0.307 0.5132 1.14 0.884 1.48 0.42 0.393 0.285 0.5451 1.52 0.705 3.28 0.269 0.413 0.515 0.2886 1.31 0.583 2.94 0.377 0.426 0.375 0.4256 1.46 0.633 3.36 PRS_PLINK_0.00398107170553497 FALSE 300.4 Dysthymic disorder Both 532 1264 5 mental disorders magenta 1264, 532 316, 137 316, 130 316, 127 316, 138 0.0256 0.0531 0.629 0.2013 1.03 0.925 1.14 -0.0223 0.15 0.882 0.05438 0.978 0.728 1.31 -0.0541 0.154 0.725 0.1394 0.947 0.701 1.28 0.049 0.151 0.746 0.1274 1.05 0.781 1.41 PRS_PLINK_0.00398107170553497 FALSE 300.8 Acute reaction to stress Both 139 475 5 mental disorders magenta 475, 139 119, 21 119, 42 118, 41 119, 35 0.148 0.107 0.167 0.7771 1.16 0.94 1.43 0.684 0.308 0.0263 1.58 1.98 1.08 3.62 0.557 0.307 0.0689 1.162 1.75 0.958 3.18 0.532 0.321 0.0973 1.012 1.7 0.908 3.19 PRS_PLINK_0.00398107170553497 FALSE 300.9 Posttraumatic stress disorder Both 117 596 5 mental disorders magenta 596, 117 149, 26 149, 29 149, 31 149, 31 0.146 0.102 0.15 0.8227 1.16 0.948 1.41 0.108 0.305 0.722 0.1415 1.11 0.613 2.02 0.261 0.304 0.39 0.4089 1.3 0.716 2.35 0.324 0.313 0.3 0.5224 1.38 0.749 2.56 PRS_PLINK_0.00398107170553497 FALSE 301 Personality disorders Both 88 387 5 mental disorders magenta 387, 88 97, 21 97, 20 96, 30 97, 17 -0.0183 0.119 0.877 0.05683 0.982 0.778 1.24 -0.0883 0.352 0.802 0.09587 0.915 0.459 1.82 0.114 0.332 0.732 0.1353 1.12 0.584 2.15 -0.171 0.367 0.641 0.1935 0.843 0.411 1.73 PRS_PLINK_0.00398107170553497 FALSE 301.2 Antisocial/borderline personality disorder Both 43 193 5 mental disorders magenta 193, 43 49, 11 48, 13 48, 14 48, 5 -0.0882 0.172 0.608 0.2161 0.916 0.654 1.28 0.0524 0.471 0.911 0.04028 1.05 0.419 2.65 -0.0793 0.507 0.876 0.05771 0.924 0.342 2.49 -0.297 0.579 0.608 0.2158 0.743 0.239 2.31 PRS_PLINK_0.00398107170553497 TRUE 302 Sexual and gender identity disorders Both 371 769 5 mental disorders magenta 769, 371 193, 68 192, 88 192, 106 192, 109 0.0923 0.0682 0.176 0.7544 1.1 0.959 1.25 0.152 0.205 0.458 0.339 1.16 0.779 1.74 0.228 0.2 0.254 0.596 1.26 0.849 1.86 0.241 0.204 0.237 0.6245 1.27 0.853 1.9 PRS_PLINK_0.00398107170553497 FALSE 302.1 Decreased libido Both 94 372 5 mental disorders magenta 372, 94 93, 17 93, 25 93, 28 93, 24 0.0529 0.119 0.658 0.1817 1.05 0.834 1.33 0.323 0.352 0.36 0.4443 1.38 0.692 2.75 0.389 0.352 0.27 0.5693 1.47 0.74 2.94 0.176 0.357 0.623 0.2057 1.19 0.592 2.4 PRS_PLINK_0.00398107170553497 FALSE 303 Psychogenic and somatoform disorders Both 1558 1380 5 mental disorders magenta 1380, 1558 345, 407 345, 399 345, 381 345, 370 -0.0262 0.0399 0.511 0.2915 0.974 0.901 1.05 -0.0317 0.109 0.77 0.1135 0.969 0.783 1.2 -0.0548 0.111 0.622 0.2059 0.947 0.761 1.18 -0.119 0.113 0.296 0.5294 0.888 0.711 1.11 PRS_PLINK_0.00398107170553497 FALSE 303.1 Dissociative disorder Both 26 132 5 mental disorders magenta 132, 26 33, 4 33, 8 33, 7 33, 7 0.148 0.204 0.467 0.3303 1.16 0.777 1.73 0.993 0.749 0.185 0.7331 2.7 0.622 11.7 0.65 0.681 0.34 0.4684 1.92 0.504 7.28 0.901 0.747 0.227 0.6433 2.46 0.57 10.6 PRS_PLINK_0.00398107170553497 TRUE 303.3 Psychogenic disorder Both 1513 1371 5 mental disorders magenta 1371, 1513 343, 394 343, 396 342, 360 343, 362 -0.0287 0.0402 0.475 0.3229 0.972 0.898 1.05 -0.0206 0.109 0.85 0.07043 0.98 0.791 1.21 -0.0704 0.113 0.534 0.2728 0.932 0.747 1.16 -0.122 0.115 0.286 0.5432 0.885 0.707 1.11 PRS_PLINK_0.00398107170553497 FALSE 303.31 Gastrointestinal malfunction arising from mental factors Both 107 415 5 mental disorders magenta 415, 107 104, 19 104, 27 103, 38 104, 23 0.0935 0.114 0.411 0.386 1.1 0.879 1.37 0.269 0.336 0.423 0.3732 1.31 0.677 2.53 0.644 0.333 0.0531 1.275 1.9 0.992 3.66 0.0892 0.376 0.813 0.09012 1.09 0.523 2.29 PRS_PLINK_0.00398107170553497 FALSE 303.4 Somatoform disorder Both 197 896 5 mental disorders magenta 896, 197 224, 55 224, 44 224, 59 224, 39 -0.0551 0.0818 0.501 0.3005 0.946 0.806 1.11 -0.249 0.228 0.274 0.5616 0.78 0.499 1.22 -0.0313 0.222 0.888 0.05175 0.969 0.627 1.5 -0.29 0.24 0.227 0.6441 0.748 0.467 1.2 PRS_PLINK_0.00398107170553497 FALSE 304 Adjustment reaction Both 784 1393 5 mental disorders magenta 1393, 784 349, 218 348, 194 348, 183 348, 189 0.0114 0.0465 0.806 0.09365 1.01 0.923 1.11 -0.0664 0.13 0.609 0.2154 0.936 0.726 1.21 -0.0912 0.133 0.491 0.3088 0.913 0.704 1.18 -0.0925 0.132 0.484 0.3149 0.912 0.703 1.18 PRS_PLINK_0.00398107170553497 FALSE 305.2 Eating disorder Both 185 769 5 mental disorders magenta 769, 185 193, 50 192, 46 192, 36 192, 53 0.118 0.0809 0.144 0.8404 1.13 0.96 1.32 -0.112 0.236 0.635 0.1973 0.894 0.563 1.42 -0.34 0.251 0.176 0.7551 0.712 0.435 1.16 0.114 0.231 0.624 0.2051 1.12 0.712 1.76 PRS_PLINK_0.00398107170553497 FALSE 306 Other mental disorder Both 386 1145 5 mental disorders magenta 1145, 386 287, 86 286, 99 286, 110 286, 91 0.0491 0.0619 0.428 0.3689 1.05 0.93 1.19 0.222 0.174 0.202 0.694 1.25 0.888 1.76 0.231 0.174 0.185 0.7333 1.26 0.896 1.77 0.0544 0.181 0.764 0.1169 1.06 0.741 1.51 PRS_PLINK_0.00398107170553497 FALSE 306.1 Mental disorders durring/after pregnancy Female 129 358 5 mental disorders magenta 358, 129 90, 28 89, 29 89, 38 90, 34 0.196 0.109 0.073 1.136 1.22 0.982 1.51 0.25 0.327 0.444 0.3529 1.28 0.677 2.44 0.38 0.312 0.223 0.6509 1.46 0.793 2.7 0.2 0.319 0.531 0.2749 1.22 0.654 2.28 PRS_PLINK_0.00398107170553497 FALSE 306.9 Tension headache Both 168 684 5 mental disorders magenta 684, 168 171, 29 171, 41 171, 61 171, 37 0.0642 0.0908 0.479 0.3194 1.07 0.893 1.27 0.322 0.269 0.231 0.6358 1.38 0.815 2.34 0.668 0.259 0.01 1.998 1.95 1.17 3.24 0.183 0.281 0.516 0.2873 1.2 0.692 2.08 PRS_PLINK_0.00398107170553497 FALSE 312 Conduct disorders Both 48 220 5 mental disorders magenta 220, 48 55, 11 55, 7 55, 17 55, 13 0.231 0.174 0.185 0.7318 1.26 0.895 1.77 -0.198 0.516 0.702 0.1538 0.821 0.299 2.26 0.467 0.48 0.331 0.4802 1.6 0.622 4.09 0.284 0.482 0.557 0.2545 1.33 0.516 3.42 PRS_PLINK_0.00398107170553497 TRUE 312.3 Impulse control disorder Both 18 89 5 mental disorders magenta 89, 18 23, 2 22, 6 22, 6 22, 4 0.0859 0.289 0.766 0.1157 1.09 0.619 1.92 0.933 0.835 0.264 0.579 2.54 0.495 13 1.2 1.06 0.26 0.5857 3.32 0.413 26.6 0.455 0.911 0.618 0.2092 1.58 0.264 9.4 PRS_PLINK_0.00398107170553497 TRUE 313 Pervasive developmental disorders Both 216 1500 5 mental disorders magenta 1500, 216 374, 55 375, 63 375, 53 375, 45 -0.0665 0.0742 0.37 0.4318 0.936 0.809 1.08 0.155 0.198 0.434 0.3624 1.17 0.792 1.72 -0.0168 0.209 0.936 0.02878 0.983 0.652 1.48 -0.185 0.219 0.398 0.4001 0.831 0.541 1.28 PRS_PLINK_0.00398107170553497 FALSE 313.1 Attention deficit hyperactivity disorder Both 185 1339 5 mental disorders magenta 1339, 185 335, 47 335, 53 334, 44 335, 41 -0.0545 0.0804 0.498 0.3031 0.947 0.809 1.11 0.139 0.213 0.516 0.2876 1.15 0.756 1.75 -0.0487 0.226 0.829 0.08119 0.952 0.611 1.48 -0.147 0.232 0.527 0.2786 0.863 0.548 1.36 PRS_PLINK_0.00398107170553497 FALSE 313.2 Tics and stuttering Both 12 53 5 mental disorders magenta 53, 12 14, 5 13, 3 13, 1 13, 3 -0.254 0.332 0.444 0.3522 0.776 0.404 1.49 -0.289 0.914 0.751 0.1241 0.749 0.125 4.49 -2.46 1.84 0.182 0.7407 0.0853 0.0023 3.16 -0.62 0.897 0.49 0.31 0.538 0.0927 3.12 PRS_PLINK_0.00398107170553497 TRUE 313.3 Autism Both 9 41 5 mental disorders magenta 41, 9 11, 4 10, 1 10, 4 10, 0 -0.448 0.503 0.373 0.4284 0.639 0.238 1.71 -1.98 1.68 0.239 0.6212 0.138 0.00512 3.73 0.0463 0.954 0.961 0.01717 1.05 0.162 6.79 -1.06 1.41 0.454 0.3431 0.347 0.0217 5.54 PRS_PLINK_0.00398107170553497 TRUE 315 Develomental delays and disorders Both 101 695 5 mental disorders magenta 695, 101 174, 17 174, 30 173, 30 174, 24 0.0402 0.109 0.711 0.1478 1.04 0.841 1.29 0.487 0.315 0.122 0.9145 1.63 0.878 3.02 0.598 0.321 0.0622 1.206 1.82 0.97 3.41 0.225 0.333 0.5 0.3013 1.25 0.652 2.4 PRS_PLINK_0.00398107170553497 FALSE 315.1 Learning disorder Both 10 77 5 mental disorders magenta 77, 10 20, 3 19, 2 19, 4 19, 1 -0.37 0.461 0.422 0.3743 0.691 0.28 1.7 -0.148 1.08 0.891 0.05019 0.863 0.105 7.12 0.207 0.917 0.821 0.08554 1.23 0.204 7.42 -0.383 1.47 0.795 0.09981 0.681 0.038 12.2 PRS_PLINK_0.00398107170553497 TRUE 315.2 Speech and language disorder Both 43 260 5 mental disorders magenta 260, 43 65, 11 65, 10 65, 12 65, 10 -0.0815 0.17 0.631 0.2 0.922 0.661 1.29 -0.267 0.464 0.566 0.2475 0.766 0.308 1.9 0.0818 0.449 0.855 0.06784 1.09 0.45 2.62 -0.278 0.468 0.553 0.2572 0.758 0.303 1.9 PRS_PLINK_0.00398107170553497 TRUE 316 Substance addiction and disorders Both 525 3415 5 mental disorders magenta 3415, 525 854, 125 854, 125 853, 133 854, 141 0.0394 0.0477 0.409 0.3884 1.04 0.947 1.14 0.0178 0.136 0.896 0.04766 1.02 0.78 1.33 0.0709 0.136 0.603 0.2199 1.07 0.822 1.4 0.161 0.137 0.24 0.6197 1.17 0.898 1.54 PRS_PLINK_0.00398107170553497 FALSE 316.1 Polyneuropathy due to drugs Both 103 775 5 mental disorders magenta 775, 103 194, 28 194, 18 193, 21 194, 36 0.0952 0.106 0.37 0.4323 1.1 0.893 1.35 -0.478 0.313 0.127 0.8964 0.62 0.336 1.15 -0.313 0.317 0.323 0.4908 0.731 0.393 1.36 0.16 0.285 0.574 0.2413 1.17 0.672 2.05 PRS_PLINK_0.00398107170553497 FALSE 317 Alcohol-related disorders Both 402 1901 5 mental disorders magenta 1901, 402 476, 107 475, 105 475, 97 475, 93 -0.0578 0.0558 0.3 0.5232 0.944 0.846 1.05 -0.0385 0.155 0.803 0.09519 0.962 0.711 1.3 -0.14 0.16 0.381 0.4189 0.87 0.636 1.19 -0.178 0.163 0.275 0.5601 0.837 0.608 1.15 PRS_PLINK_0.00398107170553497 FALSE 317.1 Alcoholism Both 336 1560 5 mental disorders magenta 1560, 336 390, 85 390, 90 390, 78 390, 83 -0.0323 0.0606 0.593 0.2266 0.968 0.86 1.09 -0.0177 0.171 0.917 0.03751 0.982 0.703 1.37 -0.131 0.179 0.464 0.3338 0.877 0.618 1.25 -0.0701 0.178 0.694 0.1585 0.932 0.658 1.32 PRS_PLINK_0.00398107170553497 FALSE 317.11 Alcoholic liver damage Both 48 335 5 mental disorders magenta 335, 48 84, 8 84, 14 83, 12 84, 14 -0.0332 0.154 0.83 0.08102 0.967 0.715 1.31 0.425 0.469 0.365 0.4374 1.53 0.61 3.84 0.326 0.47 0.488 0.3116 1.38 0.552 3.48 0.57 0.472 0.227 0.6435 1.77 0.701 4.47 PRS_PLINK_0.00398107170553497 TRUE 318 Tobacco use disorder Both 919 3728 5 mental disorders magenta 3728, 919 932, 217 932, 289 932, 214 932, 199 -0.0585 0.0383 0.127 0.8977 0.943 0.875 1.02 0.261 0.102 0.0109 1.964 1.3 1.06 1.59 -0.0832 0.11 0.45 0.3468 0.92 0.742 1.14 -0.114 0.113 0.313 0.5043 0.892 0.715 1.11 PRS_PLINK_0.00398107170553497 FALSE 320 Meningitis Both 48 424 6 neurological darkblue 424, 48 106, 13 106, 6 106, 17 106, 12 0.119 0.155 0.441 0.3552 1.13 0.831 1.53 -0.647 0.48 0.178 0.75 0.524 0.204 1.34 0.401 0.397 0.312 0.5056 1.49 0.686 3.25 -0.0325 0.425 0.939 0.02734 0.968 0.421 2.22 PRS_PLINK_0.00398107170553497 TRUE 323 Encephalitis Both 29 189 6 neurological darkblue 189, 29 48, 10 47, 3 47, 6 47, 10 0.104 0.215 0.628 0.2019 1.11 0.729 1.69 -0.962 0.65 0.139 0.8572 0.382 0.107 1.37 -0.268 0.569 0.637 0.1956 0.765 0.251 2.33 0.0786 0.568 0.89 0.05066 1.08 0.355 3.29 PRS_PLINK_0.00398107170553497 TRUE 323.8 Encephalitis, non-infectious Both 26 156 6 neurological darkblue 156, 26 39, 5 39, 4 39, 6 39, 11 0.34 0.234 0.146 0.8344 1.4 0.888 2.22 -0.162 0.772 0.834 0.07872 0.851 0.187 3.87 0.461 0.688 0.503 0.2988 1.59 0.412 6.11 1.01 0.715 0.157 0.8039 2.75 0.677 11.2 PRS_PLINK_0.00398107170553497 TRUE 324 Other CNS infection and poliomyelitis Both 32 279 6 neurological darkblue 279, 32 70, 8 70, 10 69, 6 70, 8 0.0662 0.192 0.73 0.1367 1.07 0.734 1.56 0.53 0.535 0.322 0.4916 1.7 0.595 4.85 -0.206 0.554 0.711 0.1483 0.814 0.275 2.41 0.0322 0.525 0.951 0.02178 1.03 0.369 2.89 PRS_PLINK_0.00398107170553497 TRUE 325 Phlebitis and thrombophlebitis of intracranial venous sinuses Both 6 65 6 neurological darkblue 65, 6 17, 3 16, 1 16, 0 16, 2 0.163 0.4 0.683 0.1656 1.18 0.538 2.58 -1.9 1.71 0.266 0.5757 0.149 0.00523 4.25 -1.94 1.42 0.173 0.763 0.143 0.00877 2.34 0.0913 1.05 0.931 0.03115 1.1 0.14 8.6 PRS_PLINK_0.00398107170553497 TRUE 327 Sleep disorders Both 2136 3079 6 neurological darkblue 3079, 2136 769, 507 770, 558 769, 564 770, 507 0.0211 0.0296 0.476 0.3226 1.02 0.964 1.08 0.0705 0.0823 0.392 0.4071 1.07 0.913 1.26 0.0783 0.0836 0.349 0.4571 1.08 0.918 1.27 -0.0217 0.0859 0.8 0.09671 0.979 0.827 1.16 PRS_PLINK_0.00398107170553497 FALSE 327.1 Hypersomnia Both 375 2090 6 neurological darkblue 2090, 375 523, 84 522, 93 522, 92 523, 106 0.136 0.0585 0.0204 1.69 1.15 1.02 1.28 0.116 0.165 0.48 0.3186 1.12 0.813 1.55 0.0647 0.169 0.702 0.1537 1.07 0.766 1.49 0.242 0.164 0.14 0.8526 1.27 0.923 1.76 PRS_PLINK_0.00398107170553497 FALSE 327.3 Sleep apnea Both 1186 3041 6 neurological darkblue 3041, 1186 760, 277 760, 309 760, 313 760, 287 0.0432 0.0358 0.227 0.6445 1.04 0.974 1.12 0.0732 0.1 0.465 0.333 1.08 0.884 1.31 0.0663 0.101 0.513 0.2902 1.07 0.876 1.3 -0.0296 0.104 0.776 0.1101 0.971 0.792 1.19 PRS_PLINK_0.00398107170553497 FALSE 327.31 Central/nonobstroctive sleep apnea Both 78 477 6 neurological darkblue 477, 78 120, 20 119, 17 119, 22 119, 19 -0.0301 0.127 0.813 0.09001 0.97 0.757 1.24 -0.24 0.365 0.511 0.2917 0.787 0.385 1.61 0.0817 0.346 0.813 0.0897 1.09 0.551 2.14 -0.148 0.356 0.677 0.1696 0.862 0.429 1.73 PRS_PLINK_0.00398107170553497 FALSE 327.32 Obstructive sleep apnea Both 1028 2989 6 neurological darkblue 2989, 1028 747, 237 747, 261 747, 272 747, 258 0.06 0.0378 0.112 0.9496 1.06 0.986 1.14 0.0548 0.107 0.607 0.2169 1.06 0.857 1.3 0.0628 0.107 0.559 0.2528 1.06 0.863 1.31 0.00985 0.109 0.928 0.03232 1.01 0.815 1.25 PRS_PLINK_0.00398107170553497 FALSE 327.4 Insomnia Both 1195 3049 6 neurological darkblue 3049, 1195 762, 292 762, 314 762, 320 762, 269 0.00174 0.036 0.961 0.01706 1 0.934 1.07 0.07 0.099 0.479 0.3193 1.07 0.883 1.3 0.105 0.101 0.301 0.5217 1.11 0.911 1.35 -0.0754 0.105 0.474 0.3244 0.927 0.754 1.14 PRS_PLINK_0.00398107170553497 FALSE 327.41 Organic or persistent insomnia Both 343 1397 6 neurological darkblue 1397, 343 350, 89 349, 77 349, 102 349, 75 -0.0414 0.0624 0.507 0.2947 0.959 0.849 1.08 -0.134 0.177 0.448 0.3489 0.875 0.619 1.24 0.141 0.17 0.407 0.3903 1.15 0.825 1.61 -0.196 0.183 0.282 0.5491 0.822 0.574 1.18 PRS_PLINK_0.00398107170553497 FALSE 327.5 Parasomnia Both 92 561 6 neurological darkblue 561, 92 141, 20 140, 26 140, 23 140, 23 0.117 0.112 0.296 0.5286 1.12 0.902 1.4 0.234 0.322 0.469 0.329 1.26 0.671 2.38 0.247 0.343 0.472 0.3264 1.28 0.653 2.51 0.145 0.339 0.668 0.1751 1.16 0.595 2.25 PRS_PLINK_0.00398107170553497 FALSE 327.6 Circadian rhythm sleep disorder Both 57 328 6 neurological darkblue 328, 57 82, 7 82, 20 82, 16 82, 14 0.234 0.154 0.129 0.8904 1.26 0.934 1.71 0.814 0.46 0.0768 1.115 2.26 0.916 5.56 0.827 0.491 0.0923 1.035 2.29 0.873 5.99 0.648 0.471 0.169 0.7717 1.91 0.759 4.81 PRS_PLINK_0.00398107170553497 FALSE 327.7 Sleep related movement disorders Both 323 1963 6 neurological darkblue 1963, 323 490, 69 491, 78 490, 89 491, 87 0.0905 0.0614 0.141 0.8518 1.09 0.971 1.23 0.15 0.178 0.399 0.3991 1.16 0.82 1.65 0.271 0.176 0.124 0.9055 1.31 0.928 1.85 0.25 0.179 0.161 0.7927 1.28 0.905 1.82 PRS_PLINK_0.00398107170553497 FALSE 327.71 Restless legs syndrome Both 275 1777 6 neurological darkblue 1777, 275 444, 62 444, 60 444, 84 444, 69 0.0745 0.0664 0.262 0.5815 1.08 0.946 1.23 0.00141 0.193 0.994 0.002548 1 0.686 1.46 0.342 0.184 0.0632 1.2 1.41 0.981 2.02 0.131 0.193 0.498 0.3027 1.14 0.781 1.66 PRS_PLINK_0.00398107170553497 FALSE 327.72 Sleep related leg cramps Both 27 96 6 neurological darkblue 96, 27 24, 3 24, 4 24, 7 24, 13 0.435 0.289 0.132 0.881 1.55 0.878 2.72 -0.0978 0.843 0.908 0.0421 0.907 0.174 4.73 0.665 0.809 0.411 0.386 1.94 0.398 9.48 1.16 0.716 0.105 0.9805 3.19 0.786 13 PRS_PLINK_0.00398107170553497 TRUE 331 Other cerebral degenerations Both 102 697 6 neurological darkblue 697, 102 175, 23 174, 19 174, 35 174, 25 0.028 0.104 0.788 0.1032 1.03 0.838 1.26 -0.262 0.328 0.425 0.3716 0.77 0.405 1.46 0.373 0.291 0.2 0.6999 1.45 0.821 2.57 -0.0228 0.314 0.942 0.02591 0.977 0.528 1.81 PRS_PLINK_0.00398107170553497 FALSE 331.1 Hydrocephalus Both 22 272 6 neurological darkblue 272, 22 68, 6 68, 5 68, 6 68, 5 -0.102 0.218 0.64 0.1936 0.903 0.589 1.39 -0.041 0.594 0.945 0.02454 0.96 0.299 3.08 -0.28 0.594 0.638 0.1953 0.756 0.236 2.42 -0.414 0.604 0.493 0.3069 0.661 0.202 2.16 PRS_PLINK_0.00398107170553497 TRUE 331.9 Cerebral degeneration, unspecified Both 74 407 6 neurological darkblue 407, 74 102, 18 102, 13 101, 22 102, 21 0.0394 0.127 0.756 0.1214 1.04 0.811 1.33 -0.379 0.389 0.331 0.4806 0.685 0.319 1.47 0.115 0.351 0.743 0.1292 1.12 0.564 2.23 0.0297 0.357 0.934 0.02985 1.03 0.512 2.07 PRS_PLINK_0.00398107170553497 FALSE 332 Parkinson's disease Both 57 343 6 neurological darkblue 343, 57 86, 19 86, 11 85, 13 86, 14 0.00521 0.144 0.971 0.01271 1.01 0.758 1.33 -0.542 0.406 0.182 0.74 0.581 0.262 1.29 -0.175 0.407 0.668 0.1752 0.84 0.378 1.87 -0.256 0.403 0.524 0.2803 0.774 0.352 1.7 PRS_PLINK_0.00398107170553497 FALSE 333 Extrapyramidal disease and abnormal movement disorders Both 516 3047 6 neurological darkblue 3047, 516 762, 109 762, 111 761, 152 762, 144 0.124 0.049 0.0112 1.95 1.13 1.03 1.25 0.00611 0.145 0.967 0.0148 1.01 0.757 1.34 0.327 0.139 0.0188 1.727 1.39 1.06 1.82 0.241 0.142 0.0897 1.047 1.27 0.963 1.68 PRS_PLINK_0.00398107170553497 FALSE 333.1 Essential tremor Both 141 765 6 neurological darkblue 765, 141 192, 31 191, 33 191, 32 191, 45 0.15 0.0914 0.101 0.9978 1.16 0.971 1.39 0.0649 0.271 0.811 0.09111 1.07 0.627 1.81 0.16 0.282 0.57 0.2439 1.17 0.676 2.04 0.39 0.27 0.149 0.8255 1.48 0.869 2.51 PRS_PLINK_0.00398107170553497 FALSE 333.2 Myoclonus Both 31 182 6 neurological darkblue 182, 31 46, 5 45, 3 45, 11 46, 12 0.227 0.209 0.276 0.5585 1.26 0.834 1.89 -0.167 0.738 0.821 0.0858 0.846 0.199 3.59 0.709 0.551 0.199 0.7016 2.03 0.689 5.99 0.866 0.604 0.151 0.8203 2.38 0.729 7.76 PRS_PLINK_0.00398107170553497 TRUE 333.4 Torsion dystonia Both 67 398 6 neurological darkblue 398, 67 100, 16 99, 21 99, 14 100, 16 -0.00661 0.137 0.962 0.01701 0.993 0.759 1.3 0.106 0.365 0.772 0.1121 1.11 0.543 2.27 -0.209 0.402 0.604 0.2188 0.812 0.369 1.79 -0.169 0.409 0.68 0.1676 0.845 0.379 1.88 PRS_PLINK_0.00398107170553497 FALSE 333.8 Other degenerative diseases of the basal ganglia Both 18 77 6 neurological darkblue 77, 18 20, 4 19, 3 19, 6 19, 5 0.115 0.243 0.636 0.1962 1.12 0.696 1.81 -0.18 0.789 0.82 0.08632 0.835 0.178 3.92 0.786 0.802 0.327 0.4849 2.19 0.455 10.6 0.263 0.697 0.706 0.1514 1.3 0.332 5.1 PRS_PLINK_0.00398107170553497 TRUE 334 Degenerative disease of the spinal cord Both 120 1073 6 neurological darkblue 1073, 120 269, 26 268, 35 268, 29 268, 30 0.136 0.0995 0.17 0.7695 1.15 0.943 1.39 0.454 0.277 0.101 0.9966 1.57 0.916 2.71 0.217 0.291 0.455 0.3416 1.24 0.703 2.2 0.329 0.292 0.26 0.5857 1.39 0.784 2.46 PRS_PLINK_0.00398107170553497 FALSE 334.1 Spinocerebellar disease Both 5 77 6 neurological darkblue 77, 5 20, 0 19, 1 19, 4 19, 0 0.436 0.459 0.342 0.4656 1.55 0.629 3.8 0.775 1.24 0.53 0.2754 2.17 0.193 24.4 1.61 1.18 0.17 0.7687 5.02 0.5 50.3 -0.0255 1.13 0.982 0.007894 0.975 0.107 8.88 PRS_PLINK_0.00398107170553497 TRUE 334.2 Anterior horn cell disease Both 15 98 6 neurological darkblue 98, 15 25, 5 24, 1 24, 8 25, 1 -0.121 0.33 0.714 0.1461 0.886 0.464 1.69 -2.09 1.21 0.0853 1.069 0.124 0.0114 1.34 0.42 0.718 0.559 0.2527 1.52 0.373 6.21 -1.79 1.12 0.109 0.961 0.167 0.0187 1.49 PRS_PLINK_0.00398107170553497 TRUE 334.21 Amyotrophic Lateral Sclerosis Both 8 66 6 neurological darkblue 66, 8 17, 2 16, 1 16, 4 17, 1 0.342 0.465 0.463 0.3349 1.41 0.566 3.5 -0.394 1.55 0.8 0.09717 0.675 0.0323 14.1 1.23 1.06 0.247 0.6081 3.41 0.428 27.2 1.26 1.44 0.38 0.4201 3.54 0.21 59.5 PRS_PLINK_0.00398107170553497 TRUE 335 Multiple sclerosis Both 64 495 6 neurological darkblue 495, 64 124, 15 124, 12 123, 17 124, 20 0.195 0.133 0.142 0.8472 1.21 0.937 1.58 -0.265 0.402 0.509 0.2929 0.767 0.349 1.69 0.0888 0.386 0.818 0.08729 1.09 0.513 2.33 0.362 0.385 0.347 0.4597 1.44 0.675 3.06 PRS_PLINK_0.00398107170553497 FALSE 337 Disorders of the autonomic nervous system Both 127 859 6 neurological darkblue 859, 127 215, 37 215, 24 214, 33 215, 32 -0.0278 0.0937 0.767 0.1154 0.973 0.809 1.17 -0.452 0.281 0.107 0.9689 0.636 0.367 1.1 -0.144 0.27 0.594 0.2264 0.866 0.51 1.47 -0.127 0.269 0.635 0.1969 0.88 0.52 1.49 PRS_PLINK_0.00398107170553497 FALSE 337.1 Peripheral autonomic neuropathy Both 72 449 6 neurological darkblue 449, 72 113, 22 112, 17 112, 16 112, 17 -0.114 0.128 0.372 0.4291 0.892 0.695 1.15 -0.285 0.355 0.422 0.3748 0.752 0.375 1.51 -0.387 0.378 0.305 0.5158 0.679 0.324 1.42 -0.395 0.376 0.294 0.5321 0.674 0.322 1.41 PRS_PLINK_0.00398107170553497 FALSE 338 Pain Both 2864 2361 6 neurological darkblue 2361, 2864 591, 709 590, 773 590, 725 590, 656 -0.0172 0.0294 0.559 0.2528 0.983 0.928 1.04 0.0626 0.0814 0.442 0.3546 1.06 0.908 1.25 -0.00323 0.0832 0.969 0.01365 0.997 0.847 1.17 -0.0923 0.0853 0.28 0.5536 0.912 0.771 1.08 PRS_PLINK_0.00398107170553497 FALSE 338.1 Acute pain Both 2040 2344 6 neurological darkblue 2344, 2040 586, 533 586, 523 586, 525 586, 458 -0.0329 0.032 0.304 0.5174 0.968 0.909 1.03 -0.0547 0.0893 0.541 0.2672 0.947 0.795 1.13 -0.0511 0.0903 0.571 0.2431 0.95 0.796 1.13 -0.144 0.0935 0.123 0.9112 0.866 0.721 1.04 PRS_PLINK_0.00398107170553497 FALSE 338.2 Chronic pain Both 1906 2345 6 neurological darkblue 2345, 1906 587, 456 586, 529 586, 484 586, 436 0.0077 0.0328 0.814 0.08921 1.01 0.945 1.07 0.149 0.0906 0.1 0.9995 1.16 0.972 1.39 0.0489 0.0932 0.6 0.2221 1.05 0.875 1.26 -0.0414 0.0962 0.667 0.1757 0.959 0.795 1.16 PRS_PLINK_0.00398107170553497 FALSE 339 Other headache syndromes Both 1663 3170 6 neurological darkblue 3170, 1663 793, 444 792, 414 792, 414 793, 390 -0.00141 0.0317 0.964 0.01571 0.999 0.938 1.06 -0.0262 0.0873 0.765 0.1166 0.974 0.821 1.16 0.00719 0.0888 0.935 0.02899 1.01 0.846 1.2 -0.0315 0.0908 0.729 0.1376 0.969 0.811 1.16 PRS_PLINK_0.00398107170553497 FALSE 340 Migraine Both 1241 2958 6 neurological darkblue 2958, 1241 740, 336 739, 287 739, 307 740, 310 0.017 0.0353 0.629 0.2012 1.02 0.949 1.09 -0.126 0.0982 0.198 0.7026 0.881 0.727 1.07 -0.0323 0.0989 0.744 0.1284 0.968 0.798 1.18 -0.0096 0.0999 0.923 0.0346 0.99 0.814 1.2 PRS_PLINK_0.00398107170553497 FALSE 340.1 Migrain with aura Both 771 2605 6 neurological darkblue 2605, 771 652, 207 651, 178 651, 209 651, 177 -0.0195 0.0428 0.648 0.1882 0.981 0.902 1.07 -0.149 0.118 0.205 0.6875 0.861 0.684 1.09 0.0403 0.116 0.729 0.1374 1.04 0.829 1.31 -0.124 0.121 0.307 0.5133 0.883 0.696 1.12 PRS_PLINK_0.00398107170553497 FALSE 341 Other demyelinating diseases of central nervous system Both 27 158 6 neurological darkblue 158, 27 40, 6 39, 5 39, 7 40, 9 0.0356 0.204 0.861 0.06481 1.04 0.695 1.55 -0.0655 0.629 0.917 0.03756 0.937 0.273 3.21 0.597 0.671 0.374 0.4276 1.82 0.488 6.76 -0.0139 0.62 0.982 0.007856 0.986 0.293 3.32 PRS_PLINK_0.00398107170553497 TRUE 342 Hemiplegia Both 54 467 6 neurological darkblue 467, 54 117, 15 117, 12 116, 12 117, 15 0.055 0.144 0.703 0.1532 1.06 0.796 1.4 -0.17 0.398 0.67 0.1736 0.844 0.387 1.84 -0.142 0.411 0.73 0.1366 0.868 0.388 1.94 -0.215 0.397 0.588 0.2308 0.806 0.37 1.76 PRS_PLINK_0.00398107170553497 FALSE 343 Infantile cerebral palsy Both 10 81 6 neurological darkblue 81, 10 21, 1 20, 2 20, 3 20, 4 0.928 0.394 0.0184 1.734 2.53 1.17 5.47 0.554 1.31 0.673 0.1721 1.74 0.133 22.7 0.746 1.03 0.467 0.3311 2.11 0.283 15.7 0.992 1.09 0.361 0.4423 2.7 0.321 22.7 PRS_PLINK_0.00398107170553497 TRUE 344 Other paralytic syndromes Both 93 678 6 neurological darkblue 678, 93 170, 23 169, 25 169, 20 170, 25 0.068 0.113 0.548 0.2614 1.07 0.857 1.34 0.135 0.311 0.663 0.1782 1.14 0.622 2.11 -0.086 0.33 0.795 0.09979 0.918 0.48 1.75 0.174 0.329 0.597 0.2238 1.19 0.624 2.27 PRS_PLINK_0.00398107170553497 FALSE 345 Epilepsy, recurrent seizures, convulsions Both 314 2642 6 neurological darkblue 2642, 314 661, 65 660, 75 660, 107 661, 67 0.0386 0.06 0.52 0.2837 1.04 0.924 1.17 0.139 0.177 0.433 0.3639 1.15 0.812 1.63 0.475 0.169 0.00488 2.312 1.61 1.16 2.24 -0.0533 0.187 0.776 0.1102 0.948 0.657 1.37 PRS_PLINK_0.00398107170553497 FALSE 345.1 Epilepsy Both 104 763 6 neurological darkblue 763, 104 191, 25 191, 23 190, 32 191, 24 -0.00297 0.107 0.978 0.009706 0.997 0.808 1.23 -0.0429 0.303 0.887 0.05189 0.958 0.529 1.73 0.24 0.287 0.403 0.3951 1.27 0.725 2.23 -0.187 0.309 0.545 0.2639 0.829 0.453 1.52 PRS_PLINK_0.00398107170553497 FALSE 345.11 Generalized convulsive epilepsy Both 27 208 6 neurological darkblue 208, 27 52, 7 52, 9 52, 6 52, 5 -0.22 0.216 0.308 0.5108 0.802 0.525 1.23 0.119 0.531 0.823 0.08476 1.13 0.398 3.19 -0.392 0.593 0.509 0.293 0.676 0.211 2.16 -0.471 0.616 0.445 0.3515 0.625 0.187 2.09 PRS_PLINK_0.00398107170553497 TRUE 345.12 Partial epilepsy Both 76 553 6 neurological darkblue 553, 76 139, 16 138, 18 138, 24 138, 18 0.0483 0.128 0.706 0.1512 1.05 0.817 1.35 0.287 0.373 0.442 0.3547 1.33 0.641 2.77 0.44 0.338 0.194 0.7131 1.55 0.8 3.01 -0.101 0.372 0.787 0.1043 0.904 0.436 1.87 PRS_PLINK_0.00398107170553497 FALSE 345.3 Convulsions Both 298 2468 6 neurological darkblue 2468, 298 617, 64 617, 69 617, 101 617, 64 0.0368 0.0619 0.552 0.2584 1.04 0.919 1.17 0.0667 0.181 0.713 0.1469 1.07 0.749 1.52 0.424 0.172 0.0135 1.87 1.53 1.09 2.14 -0.0971 0.191 0.61 0.2143 0.907 0.624 1.32 PRS_PLINK_0.00398107170553497 FALSE 346 Abnormal findings on study of brain and/or nervous system Both 29 188 6 neurological darkblue 188, 29 47, 8 47, 6 47, 10 47, 5 -0.047 0.199 0.813 0.08982 0.954 0.646 1.41 -0.2 0.546 0.714 0.1465 0.819 0.281 2.39 0.168 0.492 0.733 0.1349 1.18 0.451 3.1 -0.404 0.602 0.502 0.2997 0.667 0.205 2.17 PRS_PLINK_0.00398107170553497 TRUE 346.1 Nonspecific abnormal findings on radiological and other examination of skull and head Both 268 1568 6 neurological darkblue 1568, 268 392, 67 392, 63 392, 69 392, 68 -0.0079 0.0679 0.907 0.04219 0.992 0.869 1.13 -0.0642 0.189 0.734 0.1343 0.938 0.647 1.36 0.0173 0.187 0.926 0.03322 1.02 0.705 1.47 0.0613 0.191 0.748 0.1258 1.06 0.731 1.55 PRS_PLINK_0.00398107170553497 FALSE 346.2 Nonspecific abnormal results of function study of brain and central nervous system Both 17 113 6 neurological darkblue 113, 17 29, 3 28, 4 28, 5 28, 5 0.202 0.252 0.423 0.3741 1.22 0.747 2.01 0.214 0.823 0.795 0.09958 1.24 0.247 6.22 0.501 0.713 0.482 0.3168 1.65 0.408 6.68 0.726 0.756 0.338 0.4717 2.07 0.469 9.1 PRS_PLINK_0.00398107170553497 TRUE 346.3 Nonspecific abnormal findings in cerebrospinal fluid Both 13 118 6 neurological darkblue 118, 13 30, 3 29, 1 29, 8 30, 1 0.0621 0.297 0.834 0.07869 1.06 0.595 1.9 -0.414 1.04 0.691 0.1606 0.661 0.0862 5.08 1.07 0.717 0.138 0.8613 2.9 0.711 11.8 0.219 0.944 0.816 0.08811 1.25 0.196 7.92 PRS_PLINK_0.00398107170553497 TRUE 347 Cataplexy and narcolepsy Both 13 127 6 neurological darkblue 127, 13 32, 5 32, 4 31, 2 32, 2 -0.223 0.302 0.461 0.3364 0.8 0.443 1.45 0.31 0.827 0.708 0.1501 1.36 0.27 6.89 -0.898 0.781 0.25 0.6022 0.407 0.0882 1.88 -0.454 0.796 0.568 0.2453 0.635 0.133 3.02 PRS_PLINK_0.00398107170553497 TRUE 348 Other conditions of brain Both 201 1827 6 neurological darkblue 1827, 201 457, 43 457, 62 456, 46 457, 50 0.0496 0.0757 0.512 0.2906 1.05 0.906 1.22 0.427 0.211 0.043 1.367 1.53 1.01 2.32 0.0637 0.226 0.778 0.1092 1.07 0.685 1.66 0.13 0.227 0.569 0.2451 1.14 0.729 1.78 PRS_PLINK_0.00398107170553497 FALSE 348.2 Cerebral edema and compression of brain Both 68 851 6 neurological darkblue 851, 68 213, 18 213, 15 212, 18 213, 17 -0.0579 0.133 0.664 0.178 0.944 0.727 1.23 -0.158 0.353 0.654 0.1841 0.854 0.428 1.7 -0.15 0.345 0.664 0.1781 0.86 0.437 1.69 -0.219 0.375 0.56 0.252 0.804 0.386 1.68 PRS_PLINK_0.00398107170553497 FALSE 348.4 Cerebral cysts Both 35 226 6 neurological darkblue 226, 35 57, 4 56, 13 56, 7 57, 11 0.237 0.192 0.217 0.6626 1.27 0.87 1.85 1.16 0.565 0.0397 1.401 3.2 1.06 9.68 0.497 0.68 0.465 0.3324 1.64 0.433 6.24 0.86 0.627 0.17 0.7693 2.36 0.692 8.07 PRS_PLINK_0.00398107170553497 TRUE 348.7 Coma Both 38 231 6 neurological darkblue 231, 38 58, 13 58, 6 57, 13 58, 6 -0.249 0.18 0.167 0.7773 0.78 0.548 1.11 -0.764 0.523 0.144 0.8428 0.466 0.167 1.3 -0.0229 0.45 0.959 0.01801 0.977 0.404 2.36 -0.826 0.574 0.15 0.8244 0.438 0.142 1.35 PRS_PLINK_0.00398107170553497 TRUE 348.8 Encephalopathy, not elsewhere classified Both 113 872 6 neurological darkblue 872, 113 218, 24 218, 37 218, 23 218, 29 0.0485 0.0993 0.625 0.2042 1.05 0.864 1.28 0.491 0.28 0.0799 1.097 1.63 0.943 2.83 0.0327 0.311 0.916 0.03791 1.03 0.561 1.9 0.31 0.306 0.31 0.5083 1.36 0.749 2.48 PRS_PLINK_0.00398107170553497 FALSE 348.9 Other conditions of brain, NOS Both 271 2366 6 neurological darkblue 2366, 271 592, 66 591, 64 591, 58 592, 83 0.0427 0.0647 0.51 0.2924 1.04 0.919 1.18 -0.0283 0.184 0.878 0.05645 0.972 0.678 1.39 -0.119 0.192 0.535 0.2717 0.888 0.609 1.29 0.161 0.181 0.375 0.4259 1.17 0.824 1.67 PRS_PLINK_0.00398107170553497 FALSE 349 Other and unspecified disorders of the nervous system Both 133 982 6 neurological darkblue 982, 133 246, 32 245, 27 245, 37 246, 37 0.104 0.0943 0.272 0.5651 1.11 0.922 1.33 -0.0867 0.276 0.753 0.1229 0.917 0.534 1.58 0.183 0.26 0.482 0.3172 1.2 0.722 2 0.218 0.266 0.411 0.3859 1.24 0.739 2.09 PRS_PLINK_0.00398107170553497 FALSE 350 Abnormal movement Both 1142 3891 6 neurological darkblue 3891, 1142 972, 272 973, 296 972, 265 973, 309 0.0552 0.0358 0.123 0.9096 1.06 0.985 1.13 0.0413 0.0988 0.676 0.17 1.04 0.859 1.26 -0.0465 0.103 0.651 0.1866 0.955 0.78 1.17 0.0841 0.102 0.408 0.3891 1.09 0.891 1.33 PRS_PLINK_0.00398107170553497 FALSE 350.1 Abnormal involuntary movements Both 576 3231 6 neurological darkblue 3231, 576 807, 123 808, 156 807, 126 808, 171 0.115 0.047 0.0141 1.852 1.12 1.02 1.23 0.219 0.132 0.0952 1.022 1.25 0.962 1.61 0.0456 0.139 0.743 0.1292 1.05 0.797 1.37 0.299 0.133 0.025 1.602 1.35 1.04 1.75 PRS_PLINK_0.00398107170553497 FALSE 350.2 Abnormality of gait Both 682 3075 6 neurological darkblue 3075, 682 768, 175 769, 171 768, 152 769, 184 0.0238 0.0446 0.593 0.2268 1.02 0.938 1.12 -0.0596 0.123 0.628 0.2019 0.942 0.74 1.2 -0.188 0.128 0.142 0.8464 0.829 0.645 1.07 -0.0264 0.126 0.834 0.07866 0.974 0.761 1.25 PRS_PLINK_0.00398107170553497 FALSE 350.3 Lack of coordination Both 187 1138 6 neurological darkblue 1138, 187 284, 42 284, 48 284, 50 285, 47 0.0456 0.0813 0.575 0.2404 1.05 0.892 1.23 0.0816 0.228 0.721 0.1423 1.08 0.694 1.7 0.158 0.232 0.495 0.3052 1.17 0.744 1.84 0.0361 0.235 0.878 0.05638 1.04 0.653 1.64 PRS_PLINK_0.00398107170553497 FALSE 350.5 Abnormal reflex Both 42 244 6 neurological darkblue 244, 42 61, 13 61, 13 61, 8 61, 8 -0.147 0.169 0.385 0.4149 0.864 0.621 1.2 0.0345 0.436 0.937 0.02831 1.04 0.441 2.43 -0.557 0.482 0.248 0.6058 0.573 0.223 1.47 -0.551 0.473 0.244 0.6119 0.577 0.228 1.46 PRS_PLINK_0.00398107170553497 TRUE 350.6 Disturbances of sensation of smell and taste Both 82 548 6 neurological darkblue 548, 82 137, 17 137, 21 137, 17 137, 27 0.156 0.122 0.199 0.7009 1.17 0.921 1.48 0.175 0.341 0.608 0.2163 1.19 0.611 2.32 0.0967 0.367 0.792 0.1011 1.1 0.537 2.26 0.488 0.342 0.154 0.8132 1.63 0.833 3.18 PRS_PLINK_0.00398107170553497 FALSE 351 Other peripheral nerve disorders Both 1354 3281 6 neurological darkblue 3281, 1354 821, 327 820, 335 820, 323 820, 368 0.0534 0.034 0.116 0.9341 1.05 0.987 1.13 0.0287 0.0946 0.761 0.1185 1.03 0.855 1.24 -0.0226 0.0969 0.816 0.08838 0.978 0.809 1.18 0.124 0.0964 0.199 0.7022 1.13 0.937 1.37 PRS_PLINK_0.00398107170553497 FALSE 352 Disorders of other cranial nerves Both 180 1642 6 neurological darkblue 1642, 180 411, 52 410, 42 410, 42 411, 44 -0.0457 0.0804 0.569 0.2445 0.955 0.816 1.12 -0.216 0.219 0.325 0.4883 0.806 0.524 1.24 -0.212 0.219 0.334 0.4765 0.809 0.527 1.24 -0.119 0.224 0.595 0.2252 0.888 0.572 1.38 PRS_PLINK_0.00398107170553497 FALSE 352.1 Trigeminal nerve disorders [CN5] Both 90 589 6 neurological darkblue 589, 90 148, 28 147, 16 147, 23 147, 23 -0.111 0.118 0.346 0.4611 0.895 0.71 1.13 -0.567 0.335 0.091 1.041 0.567 0.294 1.09 -0.191 0.306 0.533 0.2731 0.826 0.453 1.51 -0.23 0.313 0.462 0.3352 0.795 0.431 1.47 PRS_PLINK_0.00398107170553497 FALSE 352.2 Facial nerve disorders [CN7] Both 72 789 6 neurological darkblue 789, 72 198, 19 197, 18 197, 16 197, 19 0.0599 0.125 0.632 0.199 1.06 0.831 1.36 -0.0127 0.342 0.97 0.01309 0.987 0.505 1.93 -0.141 0.355 0.69 0.1609 0.868 0.433 1.74 0.26 0.353 0.462 0.3352 1.3 0.649 2.59 PRS_PLINK_0.00398107170553497 FALSE 353 Nerve root and plexus disorders Both 744 3138 6 neurological darkblue 3138, 744 785, 175 784, 203 784, 181 785, 184 0.0118 0.0422 0.779 0.1082 1.01 0.932 1.1 0.118 0.117 0.315 0.5014 1.12 0.894 1.41 -0.012 0.121 0.921 0.03594 0.988 0.78 1.25 -0.00019 0.123 0.999 0.0005353 1 0.786 1.27 PRS_PLINK_0.00398107170553497 FALSE 353.1 Nerve plexus lesions Both 46 348 6 neurological darkblue 348, 46 87, 11 87, 13 87, 12 87, 10 0.0478 0.168 0.776 0.1104 1.05 0.755 1.46 0.232 0.434 0.592 0.2275 1.26 0.539 2.95 0.0639 0.465 0.891 0.05026 1.07 0.429 2.65 0.499 0.515 0.333 0.4777 1.65 0.6 4.52 PRS_PLINK_0.00398107170553497 TRUE 353.2 Nerve root lesions Both 20 122 6 neurological darkblue 122, 20 31, 8 30, 4 30, 4 31, 4 -0.22 0.244 0.368 0.4344 0.803 0.498 1.29 -0.584 0.67 0.383 0.4167 0.557 0.15 2.07 -0.562 0.658 0.393 0.4054 0.57 0.157 2.07 -0.436 0.66 0.508 0.2938 0.646 0.177 2.36 PRS_PLINK_0.00398107170553497 TRUE 355 Complex regional/central pain syndrome Both 81 541 6 neurological darkblue 541, 81 136, 28 135, 13 135, 14 135, 25 0.0449 0.118 0.704 0.1527 1.05 0.83 1.32 -0.65 0.348 0.0616 1.21 0.522 0.264 1.03 -0.66 0.345 0.056 1.252 0.517 0.263 1.02 -0.0433 0.311 0.889 0.05093 0.958 0.52 1.76 PRS_PLINK_0.00398107170553497 FALSE 355.1 Chronic pain syndrome Both 132 882 6 neurological darkblue 882, 132 221, 29 220, 32 220, 29 221, 42 0.224 0.0959 0.0197 1.706 1.25 1.04 1.51 0.289 0.279 0.3 0.5224 1.34 0.772 2.31 -0.0257 0.286 0.928 0.03223 0.975 0.556 1.71 0.65 0.281 0.0208 1.682 1.92 1.1 3.32 PRS_PLINK_0.00398107170553497 FALSE 356 Hereditary and idiopathic peripheral neuropathy Both 368 2282 6 neurological darkblue 2282, 368 571, 79 570, 78 570, 95 571, 116 0.131 0.0583 0.0241 1.618 1.14 1.02 1.28 -0.0278 0.171 0.871 0.06003 0.973 0.696 1.36 0.14 0.167 0.401 0.3964 1.15 0.83 1.59 0.336 0.162 0.0383 1.417 1.4 1.02 1.92 PRS_PLINK_0.00398107170553497 FALSE 357 Inflammatory and toxic neuropathy Both 491 3260 6 neurological darkblue 3260, 491 814, 100 815, 112 815, 130 815, 149 0.126 0.0504 0.0124 1.908 1.13 1.03 1.25 0.115 0.147 0.436 0.3609 1.12 0.841 1.5 0.232 0.145 0.11 0.9604 1.26 0.949 1.68 0.368 0.144 0.0107 1.97 1.45 1.09 1.92 PRS_PLINK_0.00398107170553497 FALSE 358 Myoneural disorders Both 209 1420 6 neurological darkblue 1420, 209 355, 49 355, 44 355, 63 355, 53 0.0808 0.0748 0.28 0.5529 1.08 0.936 1.26 -0.079 0.223 0.723 0.141 0.924 0.597 1.43 0.239 0.207 0.249 0.6044 1.27 0.846 1.91 0.186 0.219 0.396 0.4026 1.2 0.784 1.85 PRS_PLINK_0.00398107170553497 FALSE 358.1 Myasthenia gravis Both 15 110 6 neurological darkblue 110, 15 28, 4 27, 0 27, 6 28, 5 0.234 0.292 0.424 0.373 1.26 0.713 2.24 -1.63 1.18 0.169 0.7709 0.197 0.0194 2 -0.267 0.823 0.746 0.1274 0.766 0.153 3.84 0.0556 0.781 0.943 0.02534 1.06 0.229 4.89 PRS_PLINK_0.00398107170553497 TRUE 359 Muscular dystrophies and other myopathies Both 248 1386 6 neurological darkblue 1386, 248 347, 50 346, 61 346, 57 347, 80 0.106 0.0728 0.146 0.8356 1.11 0.964 1.28 0.253 0.206 0.219 0.6597 1.29 0.86 1.93 0.13 0.211 0.538 0.2692 1.14 0.753 1.72 0.487 0.201 0.0154 1.813 1.63 1.1 2.41 PRS_PLINK_0.00398107170553497 FALSE 359.1 Muscular dystrophies Both 7 65 6 neurological darkblue 65, 7 17, 2 16, 1 16, 2 16, 2 -0.111 0.392 0.777 0.1097 0.895 0.415 1.93 -0.412 1.1 0.707 0.1504 0.662 0.0769 5.7 -0.0513 1.08 0.962 0.01674 0.95 0.114 7.92 0.139 0.911 0.878 0.0563 1.15 0.193 6.85 PRS_PLINK_0.00398107170553497 TRUE 359.2 Myopathy Both 243 1311 6 neurological darkblue 1311, 243 328, 48 328, 60 327, 57 328, 78 0.116 0.0736 0.116 0.9356 1.12 0.972 1.3 0.293 0.21 0.163 0.7867 1.34 0.888 2.02 0.195 0.215 0.365 0.4373 1.22 0.797 1.85 0.503 0.204 0.0139 1.858 1.65 1.11 2.47 PRS_PLINK_0.00398107170553497 FALSE 360 Disorders of the globe Both 29 128 7 sense organs darkseagreen4 128, 29 32, 11 32, 3 32, 6 32, 9 -0.0839 0.219 0.702 0.1536 0.92 0.598 1.41 -1.42 0.738 0.0544 1.264 0.242 0.0569 1.03 -0.745 0.591 0.208 0.6818 0.475 0.149 1.51 -0.19 0.526 0.718 0.144 0.827 0.295 2.32 PRS_PLINK_0.00398107170553497 TRUE 360.2 Progressive myopia Both 17 75 7 sense organs darkseagreen4 75, 17 19, 8 19, 3 18, 2 19, 4 -0.167 0.294 0.57 0.2442 0.846 0.475 1.51 -1.26 0.925 0.173 0.7615 0.283 0.0462 1.74 -1.41 0.897 0.115 0.9383 0.244 0.042 1.41 -0.294 0.775 0.704 0.1524 0.745 0.163 3.4 PRS_PLINK_0.00398107170553497 TRUE 361 Retinal detachments and defects Both 166 730 7 sense organs darkseagreen4 730, 166 183, 35 182, 39 182, 46 183, 46 0.0517 0.0873 0.554 0.2564 1.05 0.887 1.25 0.157 0.258 0.544 0.2645 1.17 0.705 1.94 0.408 0.256 0.111 0.954 1.5 0.91 2.49 0.273 0.253 0.28 0.5521 1.31 0.8 2.16 PRS_PLINK_0.00398107170553497 FALSE 361.1 Retinal detachment with retinal defect Both 72 304 7 sense organs darkseagreen4 304, 72 76, 17 76, 20 76, 16 76, 19 -0.0415 0.138 0.763 0.1175 0.959 0.733 1.26 0.294 0.376 0.435 0.3617 1.34 0.642 2.8 0.109 0.399 0.784 0.1056 1.12 0.51 2.44 0.197 0.374 0.599 0.2226 1.22 0.585 2.53 PRS_PLINK_0.00398107170553497 FALSE 362 Other retinal disorders Both 800 2283 7 sense organs darkseagreen4 2283, 800 571, 200 571, 189 570, 220 571, 190 -0.0303 0.0442 0.493 0.307 0.97 0.89 1.06 -0.0454 0.123 0.711 0.148 0.956 0.751 1.22 0.137 0.121 0.258 0.5877 1.15 0.904 1.46 -0.075 0.127 0.554 0.2563 0.928 0.724 1.19 PRS_PLINK_0.00398107170553497 FALSE 362.2 Degeneration of macula and posterior pole of retina Both 515 1587 7 sense organs darkseagreen4 1587, 515 397, 124 397, 117 396, 146 397, 127 -0.0105 0.0537 0.845 0.07332 0.99 0.891 1.1 -0.075 0.152 0.622 0.2061 0.928 0.689 1.25 0.154 0.15 0.303 0.5179 1.17 0.87 1.56 -0.0122 0.156 0.938 0.02795 0.988 0.728 1.34 PRS_PLINK_0.00398107170553497 FALSE 362.21 Macular degeneration, dry Both 103 298 7 sense organs darkseagreen4 298, 103 75, 25 74, 28 74, 26 75, 24 -0.0778 0.123 0.528 0.2773 0.925 0.727 1.18 0.101 0.327 0.758 0.1205 1.11 0.582 2.1 -0.124 0.349 0.722 0.1417 0.883 0.446 1.75 -0.215 0.351 0.541 0.2672 0.807 0.406 1.6 PRS_PLINK_0.00398107170553497 FALSE 362.22 Macular degeneration, wet Both 27 106 7 sense organs darkseagreen4 106, 27 27, 6 26, 6 26, 8 27, 7 -0.00359 0.234 0.988 0.005362 0.996 0.63 1.58 -0.508 0.692 0.463 0.3345 0.602 0.155 2.34 -0.0576 0.729 0.937 0.02822 0.944 0.226 3.94 0.169 0.637 0.791 0.1019 1.18 0.34 4.12 PRS_PLINK_0.00398107170553497 TRUE 362.23 Cystoid macular degeneration of retina Both 100 384 7 sense organs darkseagreen4 384, 100 96, 18 96, 23 96, 29 96, 29 0.0782 0.11 0.475 0.3231 1.08 0.872 1.34 0.236 0.352 0.503 0.2986 1.27 0.635 2.52 0.417 0.341 0.221 0.6553 1.52 0.778 2.96 0.316 0.346 0.361 0.4425 1.37 0.696 2.7 PRS_PLINK_0.00398107170553497 FALSE 362.26 Macular puckering of retina Both 238 916 7 sense organs darkseagreen4 916, 238 229, 51 229, 56 229, 70 229, 60 0.0839 0.0748 0.262 0.5809 1.09 0.939 1.26 0.15 0.221 0.497 0.3038 1.16 0.754 1.79 0.342 0.214 0.111 0.9546 1.41 0.924 2.14 0.26 0.225 0.247 0.6075 1.3 0.835 2.02 PRS_PLINK_0.00398107170553497 FALSE 362.27 Drusen (degenerative) of retina Both 158 516 7 sense organs darkseagreen4 516, 158 129, 46 129, 40 129, 37 129, 35 -0.0746 0.0952 0.433 0.3633 0.928 0.77 1.12 -0.092 0.259 0.723 0.1411 0.912 0.549 1.52 -0.17 0.266 0.523 0.2817 0.844 0.501 1.42 -0.298 0.267 0.266 0.5755 0.743 0.44 1.25 PRS_PLINK_0.00398107170553497 FALSE 362.29 Macular degeneration (senile) of retina NOS Both 457 1483 7 sense organs darkseagreen4 1483, 457 371, 107 371, 104 370, 125 371, 120 0.00819 0.0569 0.886 0.05278 1.01 0.902 1.13 -0.0614 0.161 0.704 0.1526 0.94 0.686 1.29 0.141 0.158 0.374 0.4269 1.15 0.844 1.57 0.0544 0.163 0.739 0.1313 1.06 0.767 1.45 PRS_PLINK_0.00398107170553497 FALSE 362.3 Other nondiabetic retinopathy Both 188 880 7 sense organs darkseagreen4 880, 188 220, 38 220, 45 220, 60 220, 45 0.0816 0.0835 0.329 0.4833 1.08 0.921 1.28 0.233 0.248 0.347 0.4598 1.26 0.777 2.05 0.586 0.24 0.0148 1.829 1.8 1.12 2.88 0.253 0.252 0.316 0.4998 1.29 0.785 2.11 PRS_PLINK_0.00398107170553497 FALSE 362.31 Separation of retinal layers Both 86 388 7 sense organs darkseagreen4 388, 86 97, 17 97, 23 97, 26 97, 20 0.0423 0.12 0.725 0.1396 1.04 0.824 1.32 0.307 0.357 0.391 0.4081 1.36 0.675 2.74 0.566 0.379 0.135 0.8695 1.76 0.838 3.7 -0.0413 0.381 0.914 0.03919 0.96 0.455 2.02 PRS_PLINK_0.00398107170553497 FALSE 362.4 Retinal vascular changes and abnomalities Both 131 552 7 sense organs darkseagreen4 552, 131 138, 33 138, 31 138, 34 138, 33 -0.00236 0.0999 0.981 0.008249 0.998 0.82 1.21 -0.136 0.285 0.633 0.1987 0.873 0.499 1.53 0.0286 0.282 0.919 0.03667 1.03 0.593 1.79 -0.165 0.293 0.572 0.2425 0.848 0.478 1.5 PRS_PLINK_0.00398107170553497 FALSE 362.6 Peripheral retinal degenerations Both 106 431 7 sense organs darkseagreen4 431, 106 108, 28 108, 29 107, 28 108, 21 -0.173 0.117 0.138 0.8589 0.841 0.669 1.06 0.0548 0.302 0.856 0.06757 1.06 0.585 1.91 -0.011 0.306 0.971 0.01266 0.989 0.543 1.8 -0.347 0.338 0.304 0.5173 0.707 0.364 1.37 PRS_PLINK_0.00398107170553497 FALSE 362.7 Hereditary retinal dystrophies Both 52 245 7 sense organs darkseagreen4 245, 52 62, 9 61, 9 61, 20 61, 14 0.114 0.157 0.467 0.3311 1.12 0.825 1.52 0.168 0.521 0.746 0.127 1.18 0.427 3.28 0.746 0.441 0.091 1.041 2.11 0.888 5.01 0.198 0.505 0.695 0.1579 1.22 0.453 3.28 PRS_PLINK_0.00398107170553497 FALSE 362.8 Retinal hemorrhage/ischemia Both 59 249 7 sense organs darkseagreen4 249, 59 63, 9 62, 18 62, 19 62, 13 0.0547 0.149 0.714 0.1464 1.06 0.789 1.41 0.55 0.463 0.235 0.6291 1.73 0.7 4.29 0.728 0.44 0.0975 1.011 2.07 0.875 4.9 0.372 0.455 0.413 0.3837 1.45 0.595 3.54 PRS_PLINK_0.00398107170553497 FALSE 362.9 Retinal edema Both 54 347 7 sense organs darkseagreen4 347, 54 87, 16 87, 11 86, 14 87, 13 -0.0591 0.147 0.688 0.1624 0.943 0.706 1.26 -0.276 0.415 0.506 0.296 0.758 0.336 1.71 -0.000679 0.404 0.999 0.000583 0.999 0.453 2.21 -0.065 0.417 0.876 0.05735 0.937 0.413 2.12 PRS_PLINK_0.00398107170553497 FALSE 363 Chorioretinal inflammations, scars, and other disorders of choroid Both 107 474 7 sense organs darkseagreen4 474, 107 119, 34 118, 24 118, 25 119, 24 -0.0631 0.109 0.563 0.2493 0.939 0.758 1.16 -0.282 0.306 0.356 0.4484 0.754 0.414 1.37 -0.205 0.312 0.512 0.2906 0.815 0.442 1.5 -0.251 0.315 0.425 0.3713 0.778 0.42 1.44 PRS_PLINK_0.00398107170553497 FALSE 363.3 Chorioretinal scars Both 73 299 7 sense organs darkseagreen4 299, 73 75, 19 75, 16 74, 21 75, 17 0.0475 0.135 0.725 0.1397 1.05 0.805 1.37 0.11 0.41 0.788 0.1032 1.12 0.5 2.49 0.268 0.391 0.494 0.3062 1.31 0.607 2.81 0.166 0.412 0.686 0.1635 1.18 0.527 2.65 PRS_PLINK_0.00398107170553497 FALSE 364 Corneal opacity and other disorders of cornea Both 251 1172 7 sense organs darkseagreen4 1172, 251 293, 56 293, 72 293, 64 293, 59 -0.00277 0.0723 0.969 0.0135 0.997 0.866 1.15 0.229 0.198 0.247 0.6069 1.26 0.853 1.85 0.164 0.207 0.429 0.3671 1.18 0.785 1.77 0.0218 0.212 0.918 0.0371 1.02 0.674 1.55 PRS_PLINK_0.00398107170553497 FALSE 364.1 Corneal opacity Both 86 434 7 sense organs darkseagreen4 434, 86 109, 25 108, 21 108, 23 109, 17 -0.124 0.124 0.318 0.4974 0.883 0.692 1.13 -0.0797 0.336 0.813 0.09015 0.923 0.478 1.78 -0.00492 0.324 0.988 0.005303 0.995 0.528 1.88 -0.121 0.367 0.741 0.1301 0.886 0.431 1.82 PRS_PLINK_0.00398107170553497 FALSE 364.2 Corneal edema Both 20 102 7 sense organs darkseagreen4 102, 20 26, 8 25, 7 25, 2 26, 3 -0.238 0.277 0.389 0.4098 0.788 0.458 1.36 0.206 0.617 0.739 0.1316 1.23 0.367 4.11 -1.36 0.946 0.151 0.822 0.257 0.0402 1.64 -1.23 0.8 0.124 0.9066 0.292 0.0609 1.4 PRS_PLINK_0.00398107170553497 TRUE 364.4 Corneal degenerations Both 93 469 7 sense organs darkseagreen4 469, 93 118, 17 117, 34 117, 21 117, 21 -0.00353 0.119 0.976 0.01039 0.996 0.789 1.26 0.676 0.331 0.0414 1.383 1.97 1.03 3.76 0.274 0.36 0.448 0.3487 1.31 0.649 2.66 0.0988 0.362 0.785 0.1052 1.1 0.543 2.24 PRS_PLINK_0.00398107170553497 FALSE 364.41 Keratoconus Both 11 99 7 sense organs darkseagreen4 99, 11 25, 2 25, 4 24, 1 25, 4 0.13 0.38 0.732 0.1356 1.14 0.541 2.4 0.701 0.849 0.409 0.3881 2.02 0.382 10.7 -0.356 0.895 0.69 0.1609 0.7 0.121 4.04 0.893 0.923 0.333 0.4776 2.44 0.4 14.9 PRS_PLINK_0.00398107170553497 TRUE 364.5 Corneal dystrophy Both 118 515 7 sense organs darkseagreen4 515, 118 129, 26 129, 24 128, 35 129, 33 0.0997 0.105 0.341 0.4675 1.1 0.9 1.36 -0.118 0.311 0.704 0.1525 0.889 0.483 1.63 0.289 0.291 0.322 0.4925 1.33 0.754 2.36 0.28 0.304 0.357 0.4468 1.32 0.729 2.4 PRS_PLINK_0.00398107170553497 FALSE 364.51 Fuchs' dystrophy Both 62 282 7 sense organs darkseagreen4 282, 62 71, 17 70, 9 70, 24 71, 12 -0.0311 0.143 0.828 0.08221 0.969 0.733 1.28 -0.558 0.444 0.209 0.6791 0.573 0.24 1.37 0.313 0.366 0.393 0.406 1.37 0.667 2.8 -0.417 0.435 0.338 0.4712 0.659 0.281 1.55 PRS_PLINK_0.00398107170553497 FALSE 364.9 Cornea replaced by transplant Both 12 80 7 sense organs darkseagreen4 80, 12 20, 5 20, 3 20, 1 20, 3 -0.341 0.368 0.354 0.4513 0.711 0.346 1.46 -0.245 0.872 0.779 0.1086 0.783 0.142 4.32 -1.99 1.17 0.0877 1.057 0.136 0.0138 1.34 -0.104 0.933 0.912 0.04023 0.902 0.145 5.61 PRS_PLINK_0.00398107170553497 TRUE 365 Glaucoma Both 548 2279 7 sense organs darkseagreen4 2279, 548 570, 128 570, 130 569, 144 570, 145 0.0183 0.0492 0.711 0.1483 1.02 0.925 1.12 0.00195 0.141 0.989 0.004832 1 0.761 1.32 0.15 0.14 0.285 0.5448 1.16 0.883 1.53 0.111 0.142 0.433 0.3639 1.12 0.847 1.48 PRS_PLINK_0.00398107170553497 FALSE 365.1 Open-angle glaucoma Both 181 673 7 sense organs darkseagreen4 673, 181 169, 40 168, 52 168, 35 168, 54 0.035 0.0854 0.682 0.1664 1.04 0.876 1.22 0.227 0.24 0.343 0.4645 1.26 0.785 2.01 -0.0958 0.263 0.716 0.1451 0.909 0.542 1.52 0.34 0.246 0.166 0.7805 1.41 0.869 2.27 PRS_PLINK_0.00398107170553497 FALSE 365.11 Primary open angle glaucoma Both 96 376 7 sense organs darkseagreen4 376, 96 94, 23 94, 32 94, 15 94, 26 -0.0456 0.117 0.696 0.1577 0.955 0.76 1.2 0.382 0.314 0.225 0.6479 1.46 0.791 2.71 -0.249 0.369 0.499 0.3018 0.779 0.378 1.61 0.156 0.353 0.658 0.1818 1.17 0.585 2.33 PRS_PLINK_0.00398107170553497 FALSE 365.2 Primary angle-closure glaucoma Both 64 278 7 sense organs darkseagreen4 278, 64 70, 12 69, 17 69, 14 70, 20 -0.0457 0.144 0.752 0.124 0.955 0.72 1.27 0.181 0.422 0.669 0.1749 1.2 0.524 2.74 0.104 0.427 0.807 0.09295 1.11 0.48 2.56 0.397 0.404 0.327 0.486 1.49 0.673 3.29 PRS_PLINK_0.00398107170553497 FALSE 366 Cataract Both 1787 2678 7 sense organs darkseagreen4 2678, 1787 670, 423 669, 443 669, 446 670, 474 0.0126 0.0363 0.728 0.1379 1.01 0.943 1.09 0.0336 0.0998 0.736 0.133 1.03 0.85 1.26 0.0461 0.103 0.653 0.185 1.05 0.856 1.28 0.113 0.103 0.27 0.5683 1.12 0.916 1.37 PRS_PLINK_0.00398107170553497 FALSE 366.1 Nonsenile Cataract Both 53 180 7 sense organs darkseagreen4 180, 53 45, 10 45, 15 45, 15 45, 13 0.0689 0.172 0.688 0.1622 1.07 0.765 1.5 0.544 0.491 0.269 0.5709 1.72 0.657 4.51 0.312 0.5 0.533 0.2735 1.37 0.512 3.64 0.17 0.525 0.745 0.1276 1.19 0.424 3.32 PRS_PLINK_0.00398107170553497 FALSE 366.2 Senile cataract Both 1308 2397 7 sense organs darkseagreen4 2397, 1308 600, 296 599, 312 599, 344 599, 355 0.0268 0.0401 0.505 0.297 1.03 0.949 1.11 0.0599 0.112 0.592 0.2278 1.06 0.853 1.32 0.182 0.114 0.11 0.9598 1.2 0.96 1.5 0.202 0.115 0.0789 1.103 1.22 0.977 1.53 PRS_PLINK_0.00398107170553497 FALSE 367 Disorders of refraction and accommodation; blindness and low vision Both 2143 3089 7 sense organs darkseagreen4 3089, 2143 773, 541 772, 531 772, 548 772, 522 -0.00453 0.0293 0.877 0.05698 0.995 0.94 1.05 -0.00636 0.0811 0.938 0.02802 0.994 0.848 1.16 0.0623 0.0827 0.451 0.346 1.06 0.905 1.25 -0.00228 0.0839 0.978 0.00952 0.998 0.846 1.18 PRS_PLINK_0.00398107170553497 FALSE 367.1 Myopia Both 1318 2991 7 sense organs darkseagreen4 2991, 1318 748, 333 748, 330 747, 328 748, 327 -0.000378 0.0341 0.991 0.003856 1 0.935 1.07 0.00748 0.0943 0.937 0.02835 1.01 0.837 1.21 0.0415 0.0967 0.668 0.1754 1.04 0.862 1.26 0.012 0.0972 0.902 0.04491 1.01 0.836 1.22 PRS_PLINK_0.00398107170553497 FALSE 367.2 Astigmatism Both 1090 2899 7 sense organs darkseagreen4 2899, 1090 725, 277 725, 267 724, 288 725, 258 -0.0219 0.0369 0.553 0.2575 0.978 0.91 1.05 -0.0488 0.102 0.634 0.1982 0.952 0.779 1.16 0.0855 0.103 0.405 0.3922 1.09 0.891 1.33 -0.0605 0.106 0.567 0.2465 0.941 0.765 1.16 PRS_PLINK_0.00398107170553497 FALSE 367.8 Hypermetropia Both 571 1870 7 sense organs darkseagreen4 1870, 571 468, 147 467, 133 467, 151 468, 139 -0.0239 0.0508 0.638 0.1949 0.976 0.884 1.08 -0.0862 0.14 0.537 0.2704 0.917 0.698 1.21 0.0517 0.138 0.708 0.1501 1.05 0.804 1.38 -0.0423 0.14 0.763 0.1174 0.959 0.728 1.26 PRS_PLINK_0.00398107170553497 FALSE 367.9 Blindness and low vision Both 237 1091 7 sense organs darkseagreen4 1091, 237 273, 54 273, 52 272, 64 273, 67 0.0857 0.074 0.247 0.6081 1.09 0.942 1.26 -0.0267 0.214 0.901 0.04528 0.974 0.64 1.48 0.198 0.211 0.349 0.457 1.22 0.806 1.84 0.288 0.21 0.171 0.7665 1.33 0.883 2.01 PRS_PLINK_0.00398107170553497 FALSE 368 Visual disturbances Both 1179 3942 7 sense organs darkseagreen4 3942, 1179 985, 269 985, 273 985, 338 986, 299 0.0771 0.0349 0.0271 1.567 1.08 1.01 1.16 0.0075 0.0995 0.94 0.02693 1.01 0.829 1.22 0.271 0.0978 0.00552 2.258 1.31 1.08 1.59 0.148 0.101 0.142 0.8469 1.16 0.951 1.41 PRS_PLINK_0.00398107170553497 FALSE 368.1 Amblyopia Both 131 728 7 sense organs darkseagreen4 728, 131 182, 34 182, 27 182, 32 182, 38 0.0877 0.0992 0.377 0.4241 1.09 0.899 1.33 -0.237 0.275 0.388 0.4106 0.789 0.46 1.35 -0.0727 0.275 0.792 0.1014 0.93 0.542 1.6 0.174 0.272 0.522 0.282 1.19 0.699 2.03 PRS_PLINK_0.00398107170553497 FALSE 368.2 Diplopia and disorders of binocular vision Both 196 1121 7 sense organs darkseagreen4 1121, 196 281, 49 280, 48 280, 44 280, 55 0.0195 0.0823 0.812 0.09032 1.02 0.868 1.2 0.00898 0.222 0.968 0.01426 1.01 0.653 1.56 -0.0426 0.228 0.852 0.06962 0.958 0.612 1.5 0.199 0.223 0.373 0.4284 1.22 0.788 1.89 PRS_PLINK_0.00398107170553497 FALSE 368.3 Anisometropia Both 59 231 7 sense organs darkseagreen4 231, 59 58, 13 58, 12 57, 19 58, 15 0.0759 0.157 0.628 0.2018 1.08 0.793 1.47 -0.206 0.438 0.639 0.1945 0.814 0.345 1.92 0.29 0.407 0.475 0.3231 1.34 0.602 2.97 0.0706 0.421 0.867 0.06214 1.07 0.47 2.45 PRS_PLINK_0.00398107170553497 FALSE 368.4 Visual field defects Both 206 1242 7 sense organs darkseagreen4 1242, 206 310, 48 310, 52 310, 61 311, 45 0.0125 0.0764 0.87 0.06029 1.01 0.872 1.18 0.0637 0.217 0.769 0.1139 1.07 0.696 1.63 0.279 0.214 0.194 0.7124 1.32 0.868 2.01 -0.0489 0.229 0.831 0.08053 0.952 0.608 1.49 PRS_PLINK_0.00398107170553497 FALSE 368.9 Subjective visual disturbances Both 254 1203 7 sense organs darkseagreen4 1203, 254 301, 67 301, 56 300, 70 301, 61 -0.0431 0.0726 0.553 0.2576 0.958 0.831 1.1 -0.227 0.2 0.255 0.5933 0.797 0.538 1.18 0.0916 0.194 0.637 0.1961 1.1 0.749 1.6 -0.136 0.202 0.502 0.2995 0.873 0.587 1.3 PRS_PLINK_0.00398107170553497 FALSE 368.91 Psychophysical visual disturbances Both 18 115 7 sense organs darkseagreen4 115, 18 29, 3 29, 8 28, 4 29, 3 0.00694 0.247 0.978 0.009847 1.01 0.621 1.63 1.34 0.763 0.0799 1.097 3.81 0.853 17 0.43 0.786 0.585 0.2331 1.54 0.329 7.17 -0.189 0.834 0.821 0.08577 0.828 0.161 4.24 PRS_PLINK_0.00398107170553497 TRUE 369 Infection of the eye Both 801 2837 7 sense organs darkseagreen4 2837, 801 710, 187 709, 219 709, 223 709, 172 0.00269 0.0407 0.947 0.02348 1 0.926 1.09 0.195 0.114 0.0875 1.058 1.22 0.972 1.52 0.233 0.116 0.0451 1.346 1.26 1.01 1.58 -0.0362 0.122 0.767 0.1151 0.964 0.759 1.23 PRS_PLINK_0.00398107170553497 FALSE 369.2 Eye infection, viral Both 120 550 7 sense organs darkseagreen4 550, 120 138, 36 137, 31 137, 31 138, 22 -0.0372 0.105 0.722 0.1413 0.963 0.785 1.18 -0.246 0.288 0.393 0.4053 0.782 0.445 1.37 0.0493 0.288 0.864 0.06329 1.05 0.597 1.85 -0.29 0.313 0.354 0.4505 0.748 0.405 1.38 PRS_PLINK_0.00398107170553497 FALSE 369.5 Conjunctivitis, infectious Both 697 2628 7 sense organs darkseagreen4 2628, 697 657, 153 657, 191 657, 201 657, 152 0.0322 0.0433 0.457 0.3403 1.03 0.949 1.12 0.242 0.123 0.0485 1.314 1.27 1 1.62 0.311 0.124 0.0124 1.908 1.37 1.07 1.74 0.00793 0.131 0.952 0.0215 1.01 0.78 1.3 PRS_PLINK_0.00398107170553497 FALSE 370 Keratitis Both 339 1430 7 sense organs darkseagreen4 1430, 339 358, 88 357, 84 357, 99 358, 68 -0.0798 0.0625 0.202 0.6946 0.923 0.817 1.04 -0.0526 0.172 0.76 0.1195 0.949 0.678 1.33 0.151 0.17 0.374 0.4275 1.16 0.833 1.62 -0.27 0.183 0.141 0.852 0.764 0.534 1.09 PRS_PLINK_0.00398107170553497 FALSE 370.1 Corneal ulcer Both 58 271 7 sense organs darkseagreen4 271, 58 68, 26 68, 11 67, 11 68, 10 -0.389 0.159 0.0143 1.843 0.678 0.496 0.925 -0.902 0.408 0.0273 1.564 0.406 0.182 0.904 -0.874 0.405 0.031 1.509 0.417 0.189 0.923 -1.05 0.427 0.0138 1.859 0.35 0.152 0.807 PRS_PLINK_0.00398107170553497 FALSE 370.2 Superficial keratitis Both 149 592 7 sense organs darkseagreen4 592, 149 148, 31 148, 37 148, 44 148, 37 0.0639 0.0968 0.509 0.2932 1.07 0.882 1.29 0.142 0.273 0.603 0.2198 1.15 0.675 1.97 0.408 0.269 0.129 0.8878 1.5 0.887 2.55 0.208 0.282 0.461 0.336 1.23 0.708 2.14 PRS_PLINK_0.00398107170553497 FALSE 370.3 Keratoconjunctivitis Both 150 718 7 sense organs darkseagreen4 718, 150 180, 43 179, 36 179, 48 180, 23 -0.221 0.0932 0.0178 1.749 0.802 0.668 0.963 -0.147 0.251 0.558 0.2533 0.863 0.528 1.41 0.115 0.243 0.636 0.1965 1.12 0.697 1.81 -0.656 0.288 0.0229 1.641 0.519 0.295 0.913 PRS_PLINK_0.00398107170553497 FALSE 370.31 Keratoconjunctivitis sicca Both 55 239 7 sense organs darkseagreen4 239, 55 60, 19 60, 16 59, 12 60, 8 -0.217 0.159 0.171 0.7658 0.805 0.589 1.1 -0.131 0.389 0.736 0.1329 0.877 0.409 1.88 -0.468 0.43 0.277 0.5577 0.626 0.27 1.46 -0.829 0.464 0.0738 1.132 0.437 0.176 1.08 PRS_PLINK_0.00398107170553497 FALSE 371 Inflammation of the eye Both 1121 3056 7 sense organs darkseagreen4 3056, 1121 764, 275 764, 274 764, 335 764, 236 -0.0264 0.0365 0.468 0.3293 0.974 0.907 1.05 -0.0139 0.102 0.892 0.04974 0.986 0.808 1.2 0.24 0.101 0.0173 1.762 1.27 1.04 1.55 -0.159 0.107 0.139 0.8576 0.853 0.692 1.05 PRS_PLINK_0.00398107170553497 FALSE 371.1 Uveitis, noninfectious or NOS Both 119 601 7 sense organs darkseagreen4 601, 119 151, 29 150, 26 150, 36 150, 28 -0.0357 0.105 0.733 0.1352 0.965 0.786 1.18 -0.143 0.294 0.627 0.2025 0.867 0.487 1.54 0.264 0.278 0.342 0.466 1.3 0.755 2.25 0.0275 0.299 0.927 0.03305 1.03 0.572 1.85 PRS_PLINK_0.00398107170553497 FALSE 371.2 Conjunctivitis, noninfectious Both 268 1060 7 sense organs darkseagreen4 1060, 268 265, 51 265, 74 265, 92 265, 51 0.00976 0.0704 0.89 0.05077 1.01 0.88 1.16 0.415 0.205 0.0431 1.366 1.51 1.01 2.26 0.672 0.203 0.00092 3.036 1.96 1.32 2.91 -0.0179 0.221 0.935 0.02908 0.982 0.637 1.51 PRS_PLINK_0.00398107170553497 FALSE 371.21 Allergic conjunctivitis Both 228 897 7 sense organs darkseagreen4 897, 228 225, 46 224, 65 224, 73 224, 44 -0.0156 0.0763 0.838 0.07661 0.985 0.848 1.14 0.355 0.217 0.102 0.992 1.43 0.932 2.18 0.498 0.216 0.0215 1.668 1.64 1.08 2.51 -0.0517 0.234 0.825 0.08358 0.95 0.601 1.5 PRS_PLINK_0.00398107170553497 FALSE 371.3 Inflammation of eyelids Both 882 2644 7 sense organs darkseagreen4 2644, 882 661, 218 661, 213 661, 256 661, 194 -0.024 0.0407 0.555 0.2555 0.976 0.901 1.06 -0.0389 0.113 0.731 0.136 0.962 0.77 1.2 0.185 0.112 0.0988 1.005 1.2 0.966 1.5 -0.138 0.118 0.245 0.6111 0.872 0.691 1.1 PRS_PLINK_0.00398107170553497 FALSE 371.33 Noninfectious dermatoses of eyelid Both 49 183 7 sense organs darkseagreen4 183, 49 46, 16 46, 13 45, 12 46, 8 -0.336 0.166 0.0426 1.371 0.714 0.516 0.989 -0.172 0.435 0.693 0.1592 0.842 0.359 1.98 -0.24 0.447 0.591 0.2281 0.787 0.328 1.89 -0.863 0.524 0.0998 1.001 0.422 0.151 1.18 PRS_PLINK_0.00398107170553497 TRUE 372 Disorders of conjunctiva Both 294 1082 7 sense organs darkseagreen4 1082, 294 271, 75 270, 74 270, 86 271, 59 -0.0667 0.0679 0.325 0.4876 0.935 0.819 1.07 0.0327 0.187 0.861 0.06501 1.03 0.716 1.49 0.173 0.185 0.35 0.4558 1.19 0.827 1.71 -0.221 0.2 0.269 0.5695 0.802 0.542 1.19 PRS_PLINK_0.00398107170553497 FALSE 374 Other disorders of eyelids Both 669 2375 7 sense organs darkseagreen4 2375, 669 594, 157 594, 170 593, 201 594, 141 -0.0274 0.0462 0.552 0.2579 0.973 0.889 1.07 0.0575 0.128 0.654 0.1841 1.06 0.823 1.36 0.271 0.128 0.0337 1.473 1.31 1.02 1.68 -0.142 0.136 0.296 0.5286 0.868 0.664 1.13 PRS_PLINK_0.00398107170553497 FALSE 374.1 Ectropion or entropion Both 73 328 7 sense organs darkseagreen4 328, 73 82, 15 82, 15 82, 29 82, 14 0.121 0.134 0.367 0.4357 1.13 0.868 1.47 0.209 0.403 0.604 0.2187 1.23 0.559 2.72 0.84 0.376 0.0257 1.589 2.32 1.11 4.84 0.209 0.432 0.629 0.2011 1.23 0.528 2.87 PRS_PLINK_0.00398107170553497 FALSE 374.2 Lagophthalmos Both 26 184 7 sense organs darkseagreen4 184, 26 46, 7 46, 9 46, 6 46, 4 -0.282 0.217 0.194 0.7113 0.754 0.493 1.15 0.23 0.578 0.691 0.1603 1.26 0.405 3.91 -0.07 0.693 0.92 0.03644 0.932 0.24 3.63 0.0598 0.804 0.941 0.02653 1.06 0.219 5.14 PRS_PLINK_0.00398107170553497 TRUE 374.3 Ptosis of eyelid Both 256 1110 7 sense organs darkseagreen4 1110, 256 278, 62 277, 57 277, 78 278, 59 0.0524 0.072 0.467 0.3308 1.05 0.915 1.21 -0.0589 0.203 0.772 0.1125 0.943 0.633 1.4 0.346 0.196 0.0775 1.111 1.41 0.963 2.08 -0.019 0.207 0.927 0.03299 0.981 0.654 1.47 PRS_PLINK_0.00398107170553497 FALSE 374.6 Dermatochalasis Both 274 1067 7 sense organs darkseagreen4 1067, 274 267, 61 267, 72 266, 78 267, 63 0.0102 0.0693 0.883 0.0542 1.01 0.882 1.16 0.18 0.198 0.365 0.4377 1.2 0.811 1.77 0.314 0.198 0.113 0.9485 1.37 0.929 2.02 -0.0256 0.206 0.901 0.04522 0.975 0.651 1.46 PRS_PLINK_0.00398107170553497 FALSE 375 Disorders of lacrimal system Both 985 2628 7 sense organs darkseagreen4 2628, 985 657, 249 657, 231 657, 271 657, 233 -0.0446 0.0402 0.268 0.5718 0.956 0.884 1.03 -0.0977 0.111 0.377 0.4234 0.907 0.73 1.13 0.0474 0.111 0.669 0.1747 1.05 0.844 1.3 -0.124 0.115 0.281 0.5511 0.884 0.706 1.11 PRS_PLINK_0.00398107170553497 FALSE 375.1 Dry eyes Both 1112 2692 7 sense organs darkseagreen4 2692, 1112 673, 277 673, 257 673, 313 673, 264 -0.0277 0.0384 0.471 0.3268 0.973 0.902 1.05 -0.0969 0.106 0.363 0.4404 0.908 0.737 1.12 0.0966 0.106 0.362 0.4417 1.1 0.895 1.36 -0.102 0.11 0.355 0.4501 0.903 0.728 1.12 PRS_PLINK_0.00398107170553497 FALSE 375.2 Epiphora Both 88 437 7 sense organs darkseagreen4 437, 88 110, 23 109, 26 109, 26 109, 13 -0.179 0.121 0.138 0.8595 0.836 0.66 1.06 0.146 0.325 0.654 0.1844 1.16 0.612 2.19 0.0391 0.328 0.905 0.04334 1.04 0.547 1.98 -0.637 0.385 0.0979 1.009 0.529 0.249 1.12 PRS_PLINK_0.00398107170553497 FALSE 376 Disorders of the orbit Both 51 297 7 sense organs darkseagreen4 297, 51 75, 11 74, 14 74, 13 74, 13 0.0806 0.168 0.631 0.1999 1.08 0.78 1.51 0.296 0.431 0.491 0.3087 1.35 0.578 3.13 0.236 0.437 0.59 0.2294 1.27 0.537 2.98 0.166 0.458 0.717 0.1447 1.18 0.481 2.9 PRS_PLINK_0.00398107170553497 FALSE 377 Disorders of optic nerve and visual pathways Both 142 873 7 sense organs darkseagreen4 873, 142 219, 35 218, 37 218, 33 218, 37 0.0042 0.093 0.964 0.01595 1 0.837 1.2 0.129 0.261 0.62 0.2079 1.14 0.683 1.9 0.027 0.269 0.92 0.03617 1.03 0.607 1.74 0.207 0.272 0.447 0.3501 1.23 0.722 2.1 PRS_PLINK_0.00398107170553497 FALSE 377.1 Optic atrophy Both 62 270 7 sense organs darkseagreen4 270, 62 68, 16 67, 18 67, 14 68, 14 -0.075 0.15 0.617 0.2094 0.928 0.691 1.25 0.194 0.397 0.626 0.2037 1.21 0.557 2.64 -0.0496 0.439 0.91 0.04088 0.952 0.402 2.25 0.168 0.462 0.716 0.1448 1.18 0.478 2.93 PRS_PLINK_0.00398107170553497 FALSE 377.3 Optic neuritis/neuropathy Both 77 538 7 sense organs darkseagreen4 538, 77 135, 20 134, 21 134, 16 135, 20 -0.0418 0.125 0.739 0.1313 0.959 0.75 1.23 0.298 0.353 0.399 0.3991 1.35 0.674 2.69 -0.04 0.362 0.912 0.04001 0.961 0.473 1.95 0.232 0.361 0.521 0.2834 1.26 0.621 2.56 PRS_PLINK_0.00398107170553497 FALSE 378 Strabismus and other disorders of binocular eye movements Both 196 1113 7 sense organs darkseagreen4 1113, 196 279, 56 278, 40 278, 52 278, 48 -0.0157 0.0804 0.845 0.07316 0.984 0.841 1.15 -0.345 0.227 0.13 0.8876 0.708 0.454 1.11 0.0118 0.216 0.957 0.0193 1.01 0.662 1.55 -0.143 0.224 0.522 0.2821 0.867 0.559 1.34 PRS_PLINK_0.00398107170553497 FALSE 378.1 Strabismus (not specified as paralytic) Both 136 735 7 sense organs darkseagreen4 735, 136 184, 40 184, 23 183, 37 184, 36 0.00557 0.0973 0.954 0.02027 1.01 0.831 1.22 -0.647 0.288 0.0249 1.604 0.524 0.298 0.922 -0.076 0.257 0.767 0.1151 0.927 0.56 1.53 -0.17 0.266 0.521 0.283 0.843 0.501 1.42 PRS_PLINK_0.00398107170553497 FALSE 378.2 Nystagmus and other irregular eye movements Both 24 155 7 sense organs darkseagreen4 155, 24 39, 9 39, 6 38, 6 39, 3 -0.425 0.247 0.0861 1.065 0.654 0.403 1.06 -0.121 0.586 0.837 0.07746 0.886 0.281 2.79 -0.574 0.604 0.342 0.4664 0.563 0.172 1.84 -0.936 0.684 0.171 0.767 0.392 0.103 1.5 PRS_PLINK_0.00398107170553497 TRUE 378.5 Paralytic strabismus Both 37 291 7 sense organs darkseagreen4 291, 37 73, 9 73, 10 72, 7 73, 11 -0.0673 0.187 0.719 0.1433 0.935 0.648 1.35 -0.00403 0.472 0.993 0.002965 0.996 0.395 2.51 -0.489 0.535 0.361 0.4427 0.613 0.215 1.75 0.116 0.494 0.814 0.08947 1.12 0.426 2.96 PRS_PLINK_0.00398107170553497 TRUE 379 Other disorders of eye Both 1240 2801 7 sense organs darkseagreen4 2801, 1240 701, 305 700, 278 700, 320 700, 336 0.0358 0.0369 0.332 0.4785 1.04 0.964 1.11 -0.11 0.104 0.294 0.5318 0.896 0.73 1.1 0.0896 0.105 0.394 0.4048 1.09 0.89 1.34 0.0857 0.104 0.409 0.3885 1.09 0.889 1.34 PRS_PLINK_0.00398107170553497 FALSE 379.1 Scleritis and episcleritis Both 37 218 7 sense organs darkseagreen4 218, 37 55, 9 54, 7 54, 12 55, 9 -0.014 0.182 0.938 0.02763 0.986 0.691 1.41 -0.19 0.553 0.731 0.1361 0.827 0.28 2.44 0.161 0.493 0.743 0.1287 1.18 0.447 3.09 -0.0535 0.518 0.918 0.03732 0.948 0.344 2.61 PRS_PLINK_0.00398107170553497 TRUE 379.2 Disorders of vitreous body Both 969 2240 7 sense organs darkseagreen4 2240, 969 560, 228 560, 207 560, 265 560, 268 0.0459 0.0413 0.266 0.5746 1.05 0.966 1.14 -0.123 0.119 0.299 0.5241 0.884 0.7 1.12 0.119 0.117 0.313 0.505 1.13 0.894 1.42 0.12 0.117 0.303 0.5191 1.13 0.897 1.42 PRS_PLINK_0.00398107170553497 FALSE 379.3 Aphakia and other disorders of lens Both 32 115 7 sense organs darkseagreen4 115, 32 29, 12 29, 3 28, 9 29, 8 -0.2 0.205 0.33 0.4813 0.819 0.547 1.22 -0.993 0.668 0.137 0.8629 0.37 0.1 1.37 -0.429 0.561 0.444 0.3523 0.651 0.217 1.95 0.0537 0.633 0.932 0.03038 1.06 0.305 3.65 PRS_PLINK_0.00398107170553497 TRUE 379.4 Anomalies of pupillary function Both 47 280 7 sense organs darkseagreen4 280, 47 70, 7 70, 8 70, 15 70, 17 0.432 0.163 0.00792 2.101 1.54 1.12 2.12 -0.0228 0.519 0.965 0.01551 0.977 0.353 2.7 0.611 0.483 0.206 0.6871 1.84 0.715 4.74 0.719 0.495 0.146 0.8362 2.05 0.779 5.41 PRS_PLINK_0.00398107170553497 TRUE 379.5 Disorders of iris and ciliary body Both 62 279 7 sense organs darkseagreen4 279, 62 70, 18 70, 10 69, 24 70, 10 -0.107 0.142 0.45 0.3472 0.899 0.681 1.19 -0.246 0.458 0.591 0.2287 0.782 0.319 1.92 0.525 0.391 0.179 0.7467 1.69 0.786 3.64 -0.925 0.503 0.0659 1.181 0.396 0.148 1.06 PRS_PLINK_0.00398107170553497 FALSE 379.51 Pigmentary iris degeneration Both 23 58 7 sense organs darkseagreen4 58, 23 15, 5 14, 5 14, 5 15, 8 0.318 0.296 0.283 0.5482 1.37 0.769 2.45 0.152 0.8 0.849 0.07105 1.16 0.243 5.58 0.364 0.869 0.676 0.1703 1.44 0.262 7.9 0.788 1.07 0.46 0.3373 2.2 0.272 17.8 PRS_PLINK_0.00398107170553497 TRUE 379.9 Pain, swelling or discharge of eye Both 253 1171 7 sense organs darkseagreen4 1171, 253 293, 63 293, 69 292, 65 293, 56 -0.0206 0.0696 0.767 0.1152 0.98 0.855 1.12 0.0375 0.195 0.847 0.07209 1.04 0.709 1.52 0.0716 0.201 0.722 0.1416 1.07 0.724 1.59 -0.163 0.209 0.436 0.3604 0.85 0.564 1.28 PRS_PLINK_0.00398107170553497 FALSE 380 Disorders of external ear Both 540 2190 7 sense organs darkseagreen4 2190, 540 548, 131 547, 129 547, 141 548, 139 0.0179 0.0498 0.719 0.1435 1.02 0.923 1.12 -0.0267 0.14 0.848 0.07148 0.974 0.741 1.28 0.0566 0.14 0.685 0.1642 1.06 0.805 1.39 0.0409 0.142 0.773 0.112 1.04 0.789 1.38 PRS_PLINK_0.00398107170553497 FALSE 380.1 Otitis externa Both 278 1703 7 sense organs darkseagreen4 1703, 278 425, 72 426, 65 425, 68 426, 73 0.0308 0.0668 0.645 0.1904 1.03 0.905 1.18 -0.0949 0.185 0.607 0.2165 0.909 0.633 1.31 -0.0283 0.187 0.879 0.05582 0.972 0.674 1.4 -0.00334 0.188 0.986 0.006215 0.997 0.69 1.44 PRS_PLINK_0.00398107170553497 FALSE 380.4 Impacted cerumen Both 670 2538 7 sense organs darkseagreen4 2538, 670 635, 150 634, 166 634, 171 635, 183 0.072 0.0446 0.107 0.9714 1.07 0.985 1.17 0.0972 0.128 0.446 0.3502 1.1 0.858 1.42 0.0991 0.129 0.442 0.3542 1.1 0.858 1.42 0.156 0.13 0.229 0.6407 1.17 0.907 1.51 PRS_PLINK_0.00398107170553497 FALSE 381 Otitis media and Eustachian tube disorders Both 834 3853 7 sense organs darkseagreen4 3853, 834 963, 214 963, 205 963, 202 963, 213 0.0181 0.0389 0.642 0.1923 1.02 0.943 1.1 -0.0394 0.109 0.717 0.1445 0.961 0.777 1.19 -0.0336 0.111 0.761 0.1186 0.967 0.779 1.2 0.0336 0.111 0.762 0.118 1.03 0.832 1.29 PRS_PLINK_0.00398107170553497 FALSE 381.1 Otitis media Both 523 3194 7 sense organs darkseagreen4 3194, 523 798, 138 798, 120 798, 135 799, 130 0.0167 0.0479 0.728 0.1378 1.02 0.926 1.12 -0.132 0.135 0.327 0.485 0.876 0.672 1.14 0.019 0.134 0.888 0.0518 1.02 0.783 1.33 -0.00936 0.137 0.946 0.02426 0.991 0.757 1.3 PRS_PLINK_0.00398107170553497 FALSE 381.11 Suppurative and unspecified otitis media Both 437 2771 7 sense organs darkseagreen4 2771, 437 692, 114 693, 101 692, 114 693, 108 0.0109 0.0528 0.837 0.07721 1.01 0.912 1.12 -0.111 0.147 0.45 0.3465 0.895 0.67 1.19 0.0294 0.147 0.841 0.07506 1.03 0.772 1.37 -0.0113 0.151 0.94 0.0267 0.989 0.735 1.33 PRS_PLINK_0.00398107170553497 FALSE 381.2 Eustachian tube disorders Both 473 2202 7 sense organs darkseagreen4 2202, 473 550, 115 550, 123 550, 105 551, 130 0.047 0.0517 0.363 0.4399 1.05 0.947 1.16 0.0517 0.145 0.721 0.142 1.05 0.793 1.4 -0.0896 0.153 0.559 0.2529 0.914 0.677 1.23 0.11 0.149 0.461 0.3363 1.12 0.833 1.5 PRS_PLINK_0.00398107170553497 FALSE 381.3 Mastoiditis & related conditions Both 11 145 7 sense organs darkseagreen4 145, 11 37, 2 36, 2 36, 2 36, 5 0.245 0.282 0.385 0.415 1.28 0.735 2.22 -0.212 0.864 0.806 0.09365 0.809 0.149 4.4 0.206 0.838 0.805 0.09404 1.23 0.238 6.35 0.587 0.833 0.481 0.318 1.8 0.352 9.21 PRS_PLINK_0.00398107170553497 TRUE 381.9 Otorrhea Both 48 359 7 sense organs darkseagreen4 359, 48 90, 14 90, 8 89, 15 90, 11 0.0688 0.154 0.655 0.1835 1.07 0.792 1.45 -0.661 0.464 0.155 0.8106 0.516 0.208 1.28 0.0123 0.399 0.975 0.01082 1.01 0.464 2.21 -0.158 0.429 0.713 0.1471 0.854 0.369 1.98 PRS_PLINK_0.00398107170553497 TRUE 382 Otalgia Both 423 2371 7 sense organs darkseagreen4 2371, 423 592, 94 593, 105 592, 105 593, 119 0.0784 0.0544 0.15 0.8252 1.08 0.972 1.2 0.104 0.155 0.502 0.2996 1.11 0.819 1.5 0.0979 0.158 0.535 0.272 1.1 0.81 1.5 0.178 0.157 0.257 0.5898 1.19 0.878 1.62 PRS_PLINK_0.00398107170553497 FALSE 383 Otosclerosis Both 19 126 7 sense organs darkseagreen4 126, 19 32, 6 31, 4 31, 5 32, 4 -0.251 0.28 0.37 0.4315 0.778 0.45 1.35 -0.409 0.656 0.533 0.2731 0.664 0.184 2.4 -0.88 0.735 0.231 0.6359 0.415 0.0981 1.75 -0.433 0.667 0.516 0.287 0.648 0.175 2.4 PRS_PLINK_0.00398107170553497 TRUE 384 Other disorders of tympanic membrane Both 80 508 7 sense organs darkseagreen4 508, 80 127, 19 127, 21 127, 18 127, 22 0.0213 0.124 0.864 0.06355 1.02 0.801 1.3 0.0616 0.341 0.856 0.06731 1.06 0.546 2.07 -0.263 0.369 0.476 0.3225 0.769 0.373 1.58 0.193 0.351 0.582 0.2353 1.21 0.61 2.41 PRS_PLINK_0.00398107170553497 FALSE 384.1 Myringitis Both 10 49 7 sense organs darkseagreen4 49, 10 13, 1 12, 3 12, 1 12, 5 0.214 0.358 0.55 0.2594 1.24 0.614 2.5 0.209 1.14 0.855 0.06811 1.23 0.131 11.6 0.117 1.1 0.915 0.03852 1.12 0.13 9.7 1.17 1.05 0.263 0.5801 3.24 0.414 25.3 PRS_PLINK_0.00398107170553497 TRUE 384.4 Perforation of tympanic membrane Both 66 400 7 sense organs darkseagreen4 400, 66 100, 14 100, 18 100, 15 100, 19 0.0136 0.137 0.921 0.03581 1.01 0.775 1.33 0.155 0.38 0.684 0.165 1.17 0.554 2.46 -0.206 0.419 0.622 0.2061 0.813 0.358 1.85 0.313 0.391 0.422 0.3743 1.37 0.636 2.94 PRS_PLINK_0.00398107170553497 FALSE 385 Other disorders of middle ear and mastoid Both 46 382 7 sense organs darkseagreen4 382, 46 96, 10 95, 9 95, 12 96, 15 0.274 0.178 0.124 0.9079 1.32 0.928 1.87 -0.093 0.463 0.841 0.07523 0.911 0.368 2.26 0.155 0.445 0.727 0.1385 1.17 0.489 2.79 0.287 0.454 0.527 0.2781 1.33 0.548 3.24 PRS_PLINK_0.00398107170553497 TRUE 385.3 Cholesteatoma Both 18 202 7 sense organs darkseagreen4 202, 18 51, 4 50, 6 50, 3 51, 5 0.0234 0.263 0.929 0.03201 1.02 0.612 1.71 0.204 0.607 0.737 0.1327 1.23 0.373 4.03 -0.0523 0.74 0.944 0.02521 0.949 0.223 4.05 0.301 0.737 0.683 0.1657 1.35 0.319 5.73 PRS_PLINK_0.00398107170553497 TRUE 385.5 Tympanosclerosis and middle ear disease related to otitis media Both 11 97 7 sense organs darkseagreen4 97, 11 25, 2 24, 2 24, 5 24, 2 0.271 0.355 0.446 0.3508 1.31 0.653 2.63 -0.14 0.961 0.884 0.05356 0.869 0.132 5.72 0.613 0.844 0.467 0.3304 1.85 0.353 9.65 -0.297 1.06 0.78 0.108 0.743 0.0928 5.95 PRS_PLINK_0.00398107170553497 TRUE 386 Vertiginous syndromes and other disorders of vestibular system Both 387 2108 7 sense organs darkseagreen4 2108, 387 527, 85 527, 101 527, 90 527, 111 0.0948 0.0563 0.0922 1.035 1.1 0.985 1.23 0.159 0.161 0.324 0.489 1.17 0.855 1.61 0.0361 0.166 0.828 0.0819 1.04 0.748 1.44 0.231 0.163 0.158 0.8026 1.26 0.915 1.73 PRS_PLINK_0.00398107170553497 FALSE 386.1 Meniere's disease Both 40 370 7 sense organs darkseagreen4 370, 40 93, 11 92, 13 92, 5 93, 11 0.0218 0.177 0.902 0.04471 1.02 0.722 1.45 0.0544 0.437 0.901 0.04527 1.06 0.448 2.49 -0.579 0.528 0.273 0.5639 0.561 0.199 1.58 0.208 0.457 0.649 0.1875 1.23 0.502 3.02 PRS_PLINK_0.00398107170553497 TRUE 386.2 Peripheral or central vertigo Both 338 1843 7 sense organs darkseagreen4 1843, 338 461, 72 461, 86 460, 80 461, 100 0.105 0.0608 0.0838 1.077 1.11 0.986 1.25 0.163 0.174 0.349 0.4576 1.18 0.837 1.65 0.0736 0.178 0.679 0.1683 1.08 0.76 1.53 0.281 0.175 0.108 0.9647 1.32 0.94 1.87 PRS_PLINK_0.00398107170553497 FALSE 386.21 Central origin vertigo Both 255 1446 7 sense organs darkseagreen4 1446, 255 362, 60 361, 62 361, 63 362, 70 0.0473 0.0702 0.5 0.3009 1.05 0.914 1.2 0.00855 0.197 0.965 0.01529 1.01 0.685 1.48 0.0478 0.198 0.809 0.09212 1.05 0.712 1.55 0.147 0.199 0.461 0.3359 1.16 0.784 1.71 PRS_PLINK_0.00398107170553497 FALSE 386.3 Labyrinthitis Both 300 1707 7 sense organs darkseagreen4 1707, 300 427, 74 427, 73 426, 74 427, 79 0.0528 0.0646 0.414 0.3835 1.05 0.929 1.2 -0.0317 0.18 0.86 0.06534 0.969 0.68 1.38 0.00326 0.182 0.986 0.006266 1 0.703 1.43 0.091 0.184 0.62 0.2076 1.1 0.764 1.57 PRS_PLINK_0.00398107170553497 FALSE 386.9 Dizziness and giddiness (Light-headedness and vertigo) Both 1377 3749 7 sense organs darkseagreen4 3749, 1377 938, 338 937, 321 937, 362 937, 355 0.0518 0.033 0.117 0.9329 1.05 0.987 1.12 -0.0429 0.0939 0.648 0.1887 0.958 0.797 1.15 0.0789 0.0927 0.395 0.404 1.08 0.902 1.3 0.0442 0.094 0.639 0.1948 1.05 0.869 1.26 PRS_PLINK_0.00398107170553497 FALSE 388 Other disorders of ear Both 195 1103 7 sense organs darkseagreen4 1103, 195 276, 59 276, 51 275, 47 276, 38 -0.148 0.0821 0.071 1.149 0.862 0.734 1.01 -0.174 0.21 0.406 0.391 0.84 0.557 1.27 -0.243 0.216 0.261 0.5833 0.785 0.514 1.2 -0.527 0.229 0.0216 1.666 0.591 0.377 0.925 PRS_PLINK_0.00398107170553497 FALSE 389 Hearing loss Both 1407 3687 7 sense organs darkseagreen4 3687, 1407 921, 371 922, 330 921, 334 922, 372 -0.00892 0.0336 0.79 0.1021 0.991 0.928 1.06 -0.166 0.0934 0.0747 1.126 0.847 0.705 1.02 -0.155 0.0949 0.102 0.9896 0.856 0.711 1.03 -0.0684 0.0937 0.466 0.3319 0.934 0.777 1.12 PRS_PLINK_0.00398107170553497 FALSE 389.1 Sensorineural hearing loss Both 842 2888 7 sense organs darkseagreen4 2888, 842 721, 224 722, 203 722, 186 722, 229 -0.0195 0.0417 0.64 0.1941 0.981 0.904 1.06 -0.114 0.115 0.325 0.4882 0.893 0.712 1.12 -0.189 0.119 0.111 0.9557 0.828 0.656 1.04 -0.0826 0.116 0.475 0.3234 0.921 0.734 1.15 PRS_PLINK_0.00398107170553497 FALSE 389.2 Conductive hearing loss Both 135 855 7 sense organs darkseagreen4 855, 135 214, 36 214, 27 213, 33 214, 39 0.0248 0.096 0.796 0.09893 1.03 0.849 1.24 -0.402 0.277 0.147 0.8325 0.669 0.389 1.15 -0.134 0.266 0.615 0.2108 0.875 0.52 1.47 -0.0433 0.26 0.868 0.06167 0.958 0.576 1.59 PRS_PLINK_0.00398107170553497 FALSE 389.3 Degenerative and vascular disorders of ear Both 58 189 7 sense organs darkseagreen4 189, 58 48, 16 47, 14 47, 12 47, 16 0.0436 0.172 0.8 0.0969 1.04 0.745 1.46 0.000901 0.464 0.998 0.000673 1 0.403 2.49 -0.163 0.451 0.717 0.1445 0.849 0.351 2.06 0.278 0.476 0.559 0.2527 1.32 0.519 3.36 PRS_PLINK_0.00398107170553497 FALSE 389.4 Tinnitus Both 461 2272 7 sense organs darkseagreen4 2272, 461 567, 122 568, 111 568, 106 568, 122 -0.0136 0.0542 0.802 0.09585 0.986 0.887 1.1 -0.0858 0.146 0.557 0.2538 0.918 0.689 1.22 -0.151 0.15 0.313 0.5041 0.86 0.641 1.15 -0.0262 0.147 0.858 0.06644 0.974 0.731 1.3 PRS_PLINK_0.00398107170553497 FALSE 389.5 Disorders of acoustic nerve Both 32 150 7 sense organs darkseagreen4 150, 32 38, 7 37, 10 37, 9 38, 6 0.0767 0.214 0.72 0.1429 1.08 0.71 1.64 0.34 0.588 0.563 0.2497 1.41 0.444 4.45 0.205 0.577 0.722 0.1416 1.23 0.396 3.81 -0.077 0.612 0.9 0.04583 0.926 0.279 3.07 PRS_PLINK_0.00398107170553497 TRUE 394 Rheumatic disease of the heart valves Both 268 1324 8 circulatory system red 1324, 268 330, 62 331, 78 331, 65 331, 63 -0.0561 0.0687 0.414 0.3829 0.945 0.826 1.08 0.151 0.19 0.427 0.3696 1.16 0.801 1.69 -0.0323 0.199 0.871 0.05995 0.968 0.655 1.43 -0.0578 0.205 0.778 0.1093 0.944 0.632 1.41 PRS_PLINK_0.00398107170553497 FALSE 394.1 Mitral valve stenosis and aortic valve stenosis Both 65 280 8 circulatory system red 280, 65 69, 15 70, 20 70, 17 70, 13 -0.0678 0.135 0.614 0.2116 0.934 0.718 1.22 0.186 0.408 0.649 0.1879 1.2 0.541 2.68 0.151 0.414 0.714 0.1462 1.16 0.517 2.62 -0.155 0.448 0.73 0.1365 0.857 0.356 2.06 PRS_PLINK_0.00398107170553497 FALSE 394.2 Mitral valve disease Both 87 501 8 circulatory system red 501, 87 126, 23 125, 26 125, 20 125, 18 -0.128 0.12 0.284 0.5472 0.88 0.696 1.11 0.147 0.316 0.64 0.1935 1.16 0.624 2.15 -0.0951 0.335 0.777 0.1097 0.909 0.471 1.75 -0.275 0.343 0.424 0.3728 0.76 0.388 1.49 PRS_PLINK_0.00398107170553497 FALSE 394.3 Aortic valve disease Both 38 103 8 circulatory system red 103, 38 26, 9 26, 10 25, 12 26, 7 -0.11 0.201 0.584 0.2339 0.895 0.603 1.33 0.0609 0.591 0.918 0.03719 1.06 0.334 3.38 0.0683 0.544 0.9 0.04568 1.07 0.368 3.11 -0.284 0.652 0.663 0.1784 0.753 0.21 2.7 PRS_PLINK_0.00398107170553497 TRUE 394.4 Acute rheumatic heart disease Both 12 65 8 circulatory system red 65, 12 17, 2 16, 7 16, 2 16, 1 -0.538 0.392 0.17 0.7692 0.584 0.271 1.26 0.754 0.886 0.395 0.4037 2.13 0.374 12.1 0.403 1.07 0.706 0.1515 1.5 0.185 12.1 -1.95 1.86 0.293 0.5326 0.142 0.00371 5.42 PRS_PLINK_0.00398107170553497 TRUE 394.7 Disease of tricuspid valve Both 90 546 8 circulatory system red 546, 90 137, 21 136, 30 136, 20 137, 19 -0.0877 0.111 0.43 0.3664 0.916 0.737 1.14 0.32 0.313 0.306 0.5139 1.38 0.746 2.55 0.00836 0.333 0.98 0.008777 1.01 0.525 1.94 -0.129 0.343 0.708 0.1502 0.879 0.449 1.72 PRS_PLINK_0.00398107170553497 FALSE 395 Heart valve disorders Both 658 2974 8 circulatory system red 2974, 658 743, 152 743, 179 743, 159 744, 168 -0.0197 0.0458 0.667 0.1756 0.981 0.896 1.07 0.0945 0.125 0.45 0.3465 1.1 0.86 1.4 -0.0268 0.13 0.837 0.07745 0.974 0.754 1.26 0.000562 0.13 0.997 0.001497 1 0.775 1.29 PRS_PLINK_0.00398107170553497 FALSE 395.1 Nonrheumatic mitral valve disorders Both 400 2315 8 circulatory system red 2315, 400 578, 88 579, 115 578, 96 579, 101 -0.00834 0.0568 0.883 0.05386 0.992 0.887 1.11 0.196 0.155 0.204 0.6898 1.22 0.899 1.65 0.0251 0.162 0.877 0.05716 1.03 0.747 1.41 0.0516 0.162 0.75 0.1248 1.05 0.767 1.45 PRS_PLINK_0.00398107170553497 FALSE 395.2 Nonrheumatic aortic valve disorders Both 327 1569 8 circulatory system red 1569, 327 392, 92 392, 73 392, 86 392, 76 -0.079 0.0632 0.212 0.6746 0.924 0.816 1.05 -0.309 0.176 0.0795 1.1 0.734 0.52 1.04 -0.114 0.173 0.511 0.2916 0.892 0.635 1.25 -0.247 0.179 0.168 0.7737 0.781 0.55 1.11 PRS_PLINK_0.00398107170553497 FALSE 395.3 Nonrheumatic tricuspid valve disorders Both 82 497 8 circulatory system red 497, 82 124, 20 124, 26 124, 18 124, 18 -0.041 0.122 0.737 0.1327 0.96 0.756 1.22 0.157 0.323 0.627 0.2026 1.17 0.621 2.2 -0.0836 0.356 0.814 0.0893 0.92 0.458 1.85 -0.232 0.356 0.514 0.289 0.793 0.394 1.59 PRS_PLINK_0.00398107170553497 FALSE 395.4 Nonrheumatic pulmonary valve disorders Both 13 98 8 circulatory system red 98, 13 25, 6 24, 1 24, 3 25, 3 -0.218 0.321 0.498 0.3029 0.804 0.428 1.51 -1.15 0.9 0.201 0.6968 0.316 0.0543 1.85 -0.925 1.03 0.368 0.4346 0.397 0.053 2.97 -0.436 0.844 0.605 0.2182 0.646 0.124 3.38 PRS_PLINK_0.00398107170553497 TRUE 395.6 Heart valve replaced Both 156 831 8 circulatory system red 831, 156 208, 34 208, 39 207, 45 208, 38 0.0567 0.0895 0.527 0.2786 1.06 0.888 1.26 0.0195 0.255 0.939 0.0273 1.02 0.619 1.68 0.285 0.254 0.261 0.583 1.33 0.809 2.19 0.107 0.266 0.688 0.1625 1.11 0.661 1.87 PRS_PLINK_0.00398107170553497 FALSE 396 Abnormal heart sounds Both 866 3680 8 circulatory system red 3680, 866 919, 222 920, 218 920, 215 920, 211 -0.0573 0.0393 0.145 0.8376 0.944 0.874 1.02 -0.0434 0.108 0.688 0.1622 0.958 0.775 1.18 -0.0371 0.11 0.736 0.1334 0.964 0.777 1.2 -0.0669 0.112 0.551 0.2592 0.935 0.751 1.16 PRS_PLINK_0.00398107170553497 FALSE 401 Hypertension Both 2512 2711 8 circulatory system red 2711, 2512 677, 616 678, 613 677, 660 678, 623 0.00223 0.0321 0.945 0.02477 1 0.941 1.07 -0.0803 0.0889 0.366 0.4364 0.923 0.775 1.1 -0.00184 0.0896 0.984 0.007194 0.998 0.837 1.19 -0.0703 0.0906 0.438 0.3584 0.932 0.78 1.11 PRS_PLINK_0.00398107170553497 FALSE 401.1 Essential hypertension Both 2494 2710 8 circulatory system red 2710, 2494 677, 607 677, 613 677, 656 678, 618 0.00183 0.0322 0.955 0.02008 1 0.94 1.07 -0.065 0.0891 0.466 0.332 0.937 0.787 1.12 0.00784 0.0899 0.93 0.0313 1.01 0.845 1.2 -0.0649 0.091 0.476 0.3226 0.937 0.784 1.12 PRS_PLINK_0.00398107170553497 FALSE 401.2 Hypertensive heart and/or renal disease Both 416 1727 8 circulatory system red 1727, 416 431, 101 432, 102 431, 102 432, 111 0.0224 0.0605 0.711 0.1479 1.02 0.908 1.15 -0.0534 0.166 0.748 0.1259 0.948 0.684 1.31 -0.0227 0.168 0.893 0.0492 0.978 0.703 1.36 0.0141 0.168 0.933 0.02996 1.01 0.729 1.41 PRS_PLINK_0.00398107170553497 FALSE 401.21 Hypertensive heart disease Both 123 754 8 circulatory system red 754, 123 189, 31 188, 24 188, 33 189, 35 0.00265 0.106 0.98 0.008762 1 0.815 1.23 -0.274 0.298 0.358 0.4456 0.76 0.424 1.36 0.054 0.285 0.85 0.07078 1.06 0.604 1.84 -0.00149 0.281 0.996 0.00184 0.999 0.575 1.73 PRS_PLINK_0.00398107170553497 FALSE 401.22 Hypertensive chronic kidney disease Both 296 1507 8 circulatory system red 1507, 296 376, 70 377, 74 376, 75 377, 77 0.0575 0.0678 0.397 0.4015 1.06 0.927 1.21 0.0262 0.187 0.888 0.05139 1.03 0.712 1.48 0.0259 0.19 0.892 0.04969 1.03 0.707 1.49 0.0412 0.193 0.831 0.0802 1.04 0.713 1.52 PRS_PLINK_0.00398107170553497 FALSE 401.3 Other hypertensive complications Both 418 1908 8 circulatory system red 1908, 418 476, 110 477, 94 477, 118 477, 96 -0.0109 0.0579 0.851 0.07 0.989 0.883 1.11 -0.159 0.16 0.321 0.4929 0.853 0.624 1.17 0.00581 0.155 0.97 0.01314 1.01 0.742 1.36 -0.184 0.164 0.262 0.5818 0.832 0.603 1.15 PRS_PLINK_0.00398107170553497 FALSE 411 Ischemic Heart Disease Both 991 3370 8 circulatory system red 3370, 991 842, 232 842, 272 842, 241 843, 246 -0.0357 0.0396 0.368 0.4342 0.965 0.893 1.04 0.0815 0.108 0.45 0.3466 1.08 0.878 1.34 -0.116 0.112 0.3 0.523 0.89 0.715 1.11 -0.0845 0.115 0.461 0.3363 0.919 0.734 1.15 PRS_PLINK_0.00398107170553497 FALSE 411.1 Unstable angina (intermediate coronary syndrome) Both 95 788 8 circulatory system red 788, 95 197, 16 197, 27 197, 17 197, 35 0.181 0.107 0.0911 1.041 1.2 0.971 1.48 0.621 0.331 0.061 1.215 1.86 0.972 3.56 0.151 0.357 0.672 0.1726 1.16 0.578 2.34 0.807 0.332 0.0152 1.819 2.24 1.17 4.3 PRS_PLINK_0.00398107170553497 FALSE 411.2 Myocardial infarction Both 272 2226 8 circulatory system red 2226, 272 556, 70 556, 79 556, 52 557, 71 -0.07 0.0655 0.285 0.545 0.932 0.82 1.06 0.0822 0.177 0.643 0.1919 1.09 0.767 1.54 -0.365 0.196 0.0628 1.202 0.694 0.473 1.02 -0.0767 0.186 0.679 0.168 0.926 0.644 1.33 PRS_PLINK_0.00398107170553497 FALSE 411.3 Angina pectoris Both 270 1861 8 circulatory system red 1861, 270 466, 71 465, 68 465, 61 465, 70 -0.0474 0.0669 0.478 0.3205 0.954 0.837 1.09 -0.0563 0.183 0.759 0.1197 0.945 0.66 1.35 -0.226 0.191 0.237 0.6261 0.798 0.549 1.16 -0.0498 0.188 0.791 0.1019 0.951 0.658 1.37 PRS_PLINK_0.00398107170553497 FALSE 411.4 Coronary atherosclerosis Both 845 3061 8 circulatory system red 3061, 845 765, 192 765, 231 765, 211 765, 211 -0.0362 0.0426 0.396 0.4026 0.964 0.887 1.05 0.135 0.116 0.246 0.6096 1.14 0.911 1.44 -0.0646 0.12 0.591 0.2287 0.937 0.741 1.19 -0.0689 0.124 0.577 0.2386 0.933 0.732 1.19 PRS_PLINK_0.00398107170553497 FALSE 411.41 Aneurysm and dissection of heart Both 18 140 8 circulatory system red 140, 18 35, 3 35, 7 35, 3 35, 5 -0.000601 0.259 0.998 0.0008049 0.999 0.602 1.66 0.463 0.697 0.507 0.2953 1.59 0.405 6.22 0.0465 0.75 0.951 0.02201 1.05 0.241 4.55 0.081 0.746 0.914 0.03923 1.08 0.251 4.68 PRS_PLINK_0.00398107170553497 TRUE 411.8 Other chronic ischemic heart disease, unspecified Both 589 2783 8 circulatory system red 2783, 589 695, 133 696, 163 695, 150 696, 143 -0.0401 0.0487 0.41 0.3877 0.961 0.873 1.06 0.144 0.133 0.28 0.5534 1.16 0.889 1.5 -0.0112 0.138 0.936 0.02887 0.989 0.754 1.3 -0.0896 0.143 0.532 0.2743 0.914 0.691 1.21 PRS_PLINK_0.00398107170553497 FALSE 411.9 Other acute and subacute forms of ischemic heart disease Both 66 442 8 circulatory system red 442, 66 111, 20 110, 17 110, 15 111, 14 -0.0645 0.127 0.613 0.2129 0.937 0.73 1.2 -0.163 0.367 0.657 0.1825 0.85 0.414 1.74 -0.318 0.375 0.397 0.4017 0.727 0.349 1.52 -0.276 0.383 0.471 0.3273 0.759 0.358 1.61 PRS_PLINK_0.00398107170553497 FALSE 414 Other forms of chronic heart disease Both 454 2413 8 circulatory system red 2413, 454 603, 94 603, 132 603, 113 603, 115 0.0177 0.0528 0.737 0.1326 1.02 0.918 1.13 0.343 0.148 0.0208 1.682 1.41 1.05 1.89 0.0908 0.156 0.561 0.2512 1.1 0.806 1.49 0.169 0.157 0.282 0.5501 1.18 0.871 1.61 PRS_PLINK_0.00398107170553497 FALSE 414.2 ASCVD Both 100 647 8 circulatory system red 647, 100 162, 22 162, 32 161, 22 162, 24 0.0152 0.109 0.889 0.05085 1.02 0.82 1.26 0.37 0.298 0.214 0.6695 1.45 0.807 2.6 -0.00998 0.328 0.976 0.01068 0.99 0.521 1.88 0.0585 0.33 0.859 0.0659 1.06 0.555 2.02 PRS_PLINK_0.00398107170553497 FALSE 415 Pulmonary heart disease Both 376 3259 8 circulatory system red 3259, 376 814, 93 815, 88 814, 94 815, 101 0.0291 0.0564 0.606 0.2175 1.03 0.922 1.15 -0.0757 0.158 0.631 0.2 0.927 0.681 1.26 -0.039 0.157 0.804 0.09448 0.962 0.706 1.31 0.0711 0.157 0.65 0.1869 1.07 0.789 1.46 PRS_PLINK_0.00398107170553497 FALSE 415.1 Acute pulmonary heart disease Both 182 2016 8 circulatory system red 2016, 182 504, 54 504, 40 504, 40 504, 48 -0.0304 0.0784 0.699 0.1558 0.97 0.832 1.13 -0.283 0.217 0.193 0.7145 0.754 0.493 1.15 -0.346 0.22 0.116 0.9368 0.708 0.46 1.09 -0.114 0.212 0.59 0.2294 0.892 0.589 1.35 PRS_PLINK_0.00398107170553497 FALSE 415.11 Pulmonary embolism and infarction, acute Both 182 2014 8 circulatory system red 2014, 182 504, 55 503, 39 503, 40 504, 48 -0.0318 0.0785 0.685 0.1642 0.969 0.83 1.13 -0.322 0.218 0.14 0.8549 0.725 0.473 1.11 -0.361 0.22 0.1 0.9981 0.697 0.453 1.07 -0.126 0.211 0.55 0.26 0.881 0.582 1.33 PRS_PLINK_0.00398107170553497 FALSE 415.2 Chronic pulmonary heart disease Both 239 1954 8 circulatory system red 1954, 239 488, 51 488, 60 488, 64 489, 64 0.0599 0.0708 0.398 0.4006 1.06 0.924 1.22 0.137 0.2 0.494 0.3059 1.15 0.775 1.7 0.181 0.2 0.366 0.4362 1.2 0.809 1.77 0.211 0.203 0.298 0.5263 1.24 0.83 1.84 PRS_PLINK_0.00398107170553497 FALSE 415.21 Primary pulmonary hypertension Both 89 808 8 circulatory system red 808, 89 202, 16 202, 26 202, 23 202, 24 0.0688 0.11 0.533 0.2732 1.07 0.863 1.33 0.444 0.327 0.174 0.7604 1.56 0.822 2.96 0.332 0.337 0.325 0.4876 1.39 0.719 2.7 0.317 0.339 0.349 0.457 1.37 0.707 2.67 PRS_PLINK_0.00398107170553497 FALSE 416 Cardiomegaly Both 208 1330 8 circulatory system red 1330, 208 333, 51 332, 46 332, 58 333, 53 0.0695 0.0776 0.37 0.4314 1.07 0.921 1.25 -0.0377 0.221 0.864 0.06333 0.963 0.625 1.48 0.169 0.215 0.43 0.3667 1.18 0.778 1.8 0.0831 0.225 0.711 0.1479 1.09 0.7 1.69 PRS_PLINK_0.00398107170553497 FALSE 418 Nonspecific chest pain Both 2336 2873 8 circulatory system red 2873, 2336 718, 563 718, 591 718, 586 718, 596 0.0571 0.0296 0.054 1.267 1.06 0.999 1.12 0.0361 0.082 0.66 0.1807 1.04 0.883 1.22 0.0309 0.0838 0.713 0.1472 1.03 0.875 1.22 0.0825 0.0845 0.329 0.4823 1.09 0.92 1.28 PRS_PLINK_0.00398107170553497 FALSE 418.1 Precordial pain Both 273 1205 8 circulatory system red 1205, 273 301, 71 301, 70 301, 68 301, 64 -0.0485 0.0715 0.498 0.3032 0.953 0.828 1.1 0.00636 0.191 0.973 0.01167 1.01 0.692 1.46 -0.0878 0.194 0.651 0.1865 0.916 0.626 1.34 -0.0937 0.198 0.636 0.1963 0.911 0.618 1.34 PRS_PLINK_0.00398107170553497 FALSE 420 Carditis Both 232 1638 8 circulatory system red 1638, 232 410, 59 409, 55 409, 62 410, 56 -0.0611 0.0719 0.395 0.4031 0.941 0.817 1.08 -0.095 0.202 0.637 0.1957 0.909 0.613 1.35 0.0951 0.201 0.635 0.197 1.1 0.742 1.63 -0.0901 0.211 0.669 0.1746 0.914 0.605 1.38 PRS_PLINK_0.00398107170553497 FALSE 420.1 Myocarditis Both 16 88 8 circulatory system red 88, 16 22, 5 22, 4 22, 5 22, 2 -0.0435 0.265 0.869 0.06084 0.957 0.57 1.61 -0.174 0.791 0.826 0.08317 0.84 0.178 3.96 0.658 0.812 0.418 0.3791 1.93 0.393 9.48 -0.345 0.984 0.726 0.1394 0.708 0.103 4.87 PRS_PLINK_0.00398107170553497 TRUE 420.2 Pericarditis Both 128 890 8 circulatory system red 890, 128 223, 31 222, 28 222, 38 223, 31 -0.0135 0.0954 0.887 0.05183 0.987 0.818 1.19 -0.0983 0.279 0.725 0.1398 0.906 0.524 1.57 0.275 0.27 0.309 0.5105 1.32 0.775 2.23 0.112 0.289 0.699 0.1552 1.12 0.634 1.97 PRS_PLINK_0.00398107170553497 FALSE 420.21 Acute pericarditis Both 34 180 8 circulatory system red 180, 34 45, 17 45, 3 45, 8 45, 6 -0.273 0.2 0.171 0.7676 0.761 0.515 1.13 -1.68 0.668 0.0119 1.923 0.186 0.0503 0.691 -0.345 0.505 0.494 0.3059 0.708 0.263 1.91 -0.907 0.548 0.098 1.009 0.404 0.138 1.18 PRS_PLINK_0.00398107170553497 TRUE 420.22 Chronic pericarditis Both 13 124 8 circulatory system red 124, 13 31, 3 31, 4 31, 4 31, 2 -0.482 0.307 0.117 0.9331 0.617 0.338 1.13 0.462 0.817 0.572 0.2424 1.59 0.32 7.87 -0.297 1.01 0.77 0.1136 0.743 0.102 5.43 0.539 1.06 0.61 0.2148 1.71 0.216 13.6 PRS_PLINK_0.00398107170553497 TRUE 420.3 Endocarditis Both 108 792 8 circulatory system red 792, 108 198, 23 198, 36 198, 25 198, 24 -0.0796 0.104 0.444 0.3529 0.923 0.753 1.13 0.375 0.285 0.188 0.7264 1.46 0.833 2.54 0.0254 0.307 0.934 0.02966 1.03 0.562 1.87 -0.0725 0.315 0.818 0.08734 0.93 0.502 1.72 PRS_PLINK_0.00398107170553497 FALSE 425 Cardiomyopathy Both 245 1935 8 circulatory system red 1935, 245 484, 60 484, 70 483, 62 484, 53 -0.0583 0.0706 0.409 0.388 0.943 0.821 1.08 0.102 0.188 0.586 0.2323 1.11 0.766 1.6 -0.0632 0.196 0.748 0.1263 0.939 0.639 1.38 -0.157 0.204 0.442 0.3551 0.855 0.574 1.27 PRS_PLINK_0.00398107170553497 FALSE 425.1 Primary/intrinsic cardiomyopathies Both 236 1836 8 circulatory system red 1836, 236 459, 60 459, 69 459, 59 459, 48 -0.0973 0.072 0.177 0.7531 0.907 0.788 1.04 0.101 0.189 0.594 0.2264 1.11 0.764 1.6 -0.0985 0.199 0.62 0.2075 0.906 0.614 1.34 -0.257 0.209 0.218 0.6609 0.773 0.514 1.16 PRS_PLINK_0.00398107170553497 FALSE 425.11 Hypertrophic obstructive cardiomyopathy Both 20 193 8 circulatory system red 193, 20 49, 4 48, 4 48, 5 48, 7 0.0427 0.242 0.86 0.06556 1.04 0.65 1.68 0.118 0.638 0.853 0.06883 1.13 0.322 3.93 0.196 0.651 0.763 0.1173 1.22 0.34 4.35 0.333 0.622 0.592 0.2274 1.4 0.412 4.73 PRS_PLINK_0.00398107170553497 TRUE 425.12 Other hypertrophic cardiomyopathy Both 24 218 8 circulatory system red 218, 24 55, 9 54, 5 54, 6 55, 4 -0.306 0.215 0.154 0.8125 0.736 0.483 1.12 -0.463 0.551 0.4 0.3974 0.629 0.214 1.85 -0.426 0.56 0.447 0.3501 0.653 0.218 1.96 -0.772 0.609 0.205 0.6878 0.462 0.14 1.53 PRS_PLINK_0.00398107170553497 TRUE 425.2 Secondary/extrinsic cardiomyopathies Both 32 299 8 circulatory system red 299, 32 75, 3 75, 10 74, 8 75, 11 0.285 0.173 0.0997 1.001 1.33 0.947 1.87 1.27 0.652 0.0508 1.294 3.57 0.995 12.8 0.97 0.618 0.117 0.9336 2.64 0.786 8.86 1.24 0.605 0.0401 1.397 3.46 1.06 11.3 PRS_PLINK_0.00398107170553497 TRUE 425.8 Other cardiomyopathy Both 18 102 8 circulatory system red 102, 18 26, 5 25, 5 25, 6 26, 2 -0.315 0.28 0.261 0.5831 0.73 0.421 1.26 0.435 0.73 0.551 0.2587 1.54 0.37 6.45 0.182 0.696 0.794 0.1004 1.2 0.307 4.69 -0.238 0.794 0.764 0.1169 0.788 0.166 3.74 PRS_PLINK_0.00398107170553497 TRUE 426 Cardiac conduction disorders Both 1816 2171 8 circulatory system red 2171, 1816 542, 479 543, 432 542, 503 543, 402 -0.0587 0.0359 0.102 0.9908 0.943 0.879 1.01 -0.192 0.0985 0.0518 1.286 0.826 0.681 1 -0.00959 0.0989 0.923 0.03493 0.99 0.816 1.2 -0.304 0.103 0.0032 2.495 0.738 0.603 0.903 PRS_PLINK_0.00398107170553497 FALSE 426.2 Atrioventricular [AV] block Both 214 800 8 circulatory system red 800, 214 200, 48 200, 49 200, 48 200, 69 0.0983 0.0867 0.257 0.59 1.1 0.931 1.31 -0.0421 0.243 0.863 0.06417 0.959 0.595 1.54 -0.124 0.248 0.617 0.21 0.883 0.543 1.44 0.128 0.238 0.591 0.2281 1.14 0.712 1.81 PRS_PLINK_0.00398107170553497 FALSE 426.21 First degree AV block Both 126 582 8 circulatory system red 582, 126 146, 25 145, 31 145, 27 146, 43 0.144 0.107 0.179 0.7467 1.16 0.936 1.43 0.156 0.307 0.611 0.2143 1.17 0.641 2.13 -0.0573 0.323 0.859 0.06584 0.944 0.501 1.78 0.334 0.3 0.265 0.576 1.4 0.776 2.51 PRS_PLINK_0.00398107170553497 FALSE 426.22 Mobitz II AV block Both 12 39 8 circulatory system red 39, 12 10, 2 10, 0 9, 3 10, 7 0.327 0.348 0.346 0.4603 1.39 0.702 2.74 -0.68 1.34 0.613 0.2126 0.506 0.0363 7.07 -0.264 1.24 0.831 0.08044 0.768 0.068 8.67 0.585 1.02 0.568 0.246 1.79 0.242 13.3 PRS_PLINK_0.00398107170553497 TRUE 426.23 Second degree AV block Both 30 120 8 circulatory system red 120, 30 30, 4 30, 8 30, 8 30, 10 0.114 0.222 0.608 0.2161 1.12 0.725 1.73 0.504 0.668 0.451 0.3459 1.65 0.447 6.13 0.899 0.755 0.234 0.6312 2.46 0.56 10.8 0.517 0.755 0.494 0.3067 1.68 0.382 7.36 PRS_PLINK_0.00398107170553497 TRUE 426.24 Atrioventricular block, complete Both 59 243 8 circulatory system red 243, 59 61, 19 61, 10 60, 11 61, 19 0.0663 0.168 0.693 0.1592 1.07 0.769 1.48 -0.758 0.455 0.0954 1.02 0.468 0.192 1.14 -0.617 0.448 0.169 0.7726 0.54 0.224 1.3 -0.202 0.414 0.625 0.2041 0.817 0.363 1.84 PRS_PLINK_0.00398107170553497 FALSE 426.25 Other heart block Both 34 108 8 circulatory system red 108, 34 27, 10 27, 6 27, 4 27, 14 -0.0545 0.232 0.815 0.08903 0.947 0.601 1.49 -0.697 0.679 0.305 0.5163 0.498 0.132 1.88 -1.47 0.832 0.0771 1.113 0.23 0.0451 1.17 -0.0871 0.605 0.886 0.05281 0.917 0.28 3 PRS_PLINK_0.00398107170553497 TRUE 426.3 Bundle branch block Both 268 1065 8 circulatory system red 1065, 268 266, 61 266, 64 266, 75 266, 68 0.04 0.0737 0.587 0.2312 1.04 0.901 1.2 -0.0772 0.21 0.713 0.1468 0.926 0.613 1.4 0.13 0.204 0.523 0.2813 1.14 0.764 1.7 -0.0664 0.212 0.754 0.1227 0.936 0.618 1.42 PRS_PLINK_0.00398107170553497 FALSE 426.31 Right bundle branch block Both 158 746 8 circulatory system red 746, 158 187, 41 186, 39 186, 36 187, 42 -0.0376 0.0927 0.685 0.1642 0.963 0.803 1.16 -0.0686 0.255 0.788 0.1036 0.934 0.567 1.54 -0.163 0.259 0.529 0.2763 0.85 0.511 1.41 -0.0861 0.253 0.734 0.1344 0.917 0.558 1.51 PRS_PLINK_0.00398107170553497 FALSE 426.32 Left bundle branch block Both 118 598 8 circulatory system red 598, 118 150, 22 149, 26 149, 41 150, 29 0.119 0.11 0.28 0.5527 1.13 0.907 1.4 0.11 0.321 0.733 0.1352 1.12 0.595 2.09 0.437 0.296 0.14 0.853 1.55 0.866 2.77 0.0798 0.313 0.799 0.09745 1.08 0.586 2 PRS_PLINK_0.00398107170553497 FALSE 426.4 Anomalous atrioventricular excitation Both 7 47 8 circulatory system red 47, 7 12, 2 12, 2 11, 2 12, 1 -0.521 0.541 0.336 0.4743 0.594 0.205 1.72 0.568 1.37 0.678 0.1685 1.77 0.12 25.9 0.507 1.41 0.72 0.1426 1.66 0.104 26.5 -1.45 1.83 0.427 0.3694 0.234 0.00653 8.42 PRS_PLINK_0.00398107170553497 TRUE 426.7 Abnormal electrocardiogram [ECG] [EKG] Both 1672 2168 8 circulatory system red 2168, 1672 541, 441 542, 398 542, 461 542, 372 -0.0612 0.0367 0.0957 1.019 0.941 0.875 1.01 -0.195 0.101 0.0532 1.274 0.823 0.676 1 -0.00241 0.101 0.981 0.008346 0.998 0.818 1.22 -0.303 0.106 0.00408 2.389 0.739 0.601 0.908 PRS_PLINK_0.00398107170553497 FALSE 426.8 Other cardiac conduction disorders Both 107 557 8 circulatory system red 557, 107 140, 33 139, 23 139, 34 139, 17 -0.229 0.108 0.0348 1.459 0.795 0.643 0.984 -0.334 0.304 0.272 0.5648 0.716 0.394 1.3 0.101 0.289 0.727 0.1386 1.11 0.627 1.95 -0.77 0.333 0.0209 1.681 0.463 0.241 0.89 PRS_PLINK_0.00398107170553497 FALSE 426.9 Cardiac pacemaker/device in situ Both 163 779 8 circulatory system red 779, 163 195, 36 195, 45 194, 46 195, 36 -0.0205 0.0982 0.835 0.07853 0.98 0.808 1.19 0.119 0.256 0.641 0.1933 1.13 0.683 1.86 0.11 0.267 0.68 0.1672 1.12 0.662 1.88 -0.114 0.271 0.674 0.1712 0.892 0.525 1.52 PRS_PLINK_0.00398107170553497 FALSE 426.91 Cardiac pacemaker in situ Both 115 530 8 circulatory system red 530, 115 133, 26 132, 27 132, 32 133, 30 -0.00293 0.116 0.98 0.008856 0.997 0.794 1.25 -0.133 0.314 0.671 0.173 0.875 0.473 1.62 0.0563 0.308 0.855 0.06795 1.06 0.578 1.94 -0.0615 0.312 0.844 0.07382 0.94 0.511 1.73 PRS_PLINK_0.00398107170553497 FALSE 426.92 Cardiac defibrillator in situ Both 77 438 8 circulatory system red 438, 77 110, 14 109, 25 109, 26 110, 12 -0.0811 0.139 0.558 0.2532 0.922 0.703 1.21 0.423 0.36 0.24 0.6189 1.53 0.753 3.09 0.315 0.375 0.4 0.398 1.37 0.658 2.86 -0.35 0.416 0.4 0.3985 0.704 0.312 1.59 PRS_PLINK_0.00398107170553497 FALSE 427 Cardiac dysrhythmias Both 2553 2199 8 circulatory system red 2199, 2553 549, 668 550, 627 549, 694 550, 564 -0.0499 0.0313 0.11 0.9569 0.951 0.895 1.01 -0.134 0.0867 0.124 0.9081 0.875 0.738 1.04 0.0241 0.0873 0.783 0.1063 1.02 0.863 1.22 -0.244 0.0903 0.00702 2.153 0.784 0.657 0.936 PRS_PLINK_0.00398107170553497 FALSE 427.1 Paroxysmal tachycardia, unspecified Both 365 1471 8 circulatory system red 1471, 365 367, 106 368, 87 367, 96 368, 76 -0.104 0.0625 0.0953 1.021 0.901 0.797 1.02 -0.258 0.169 0.126 0.8986 0.772 0.555 1.08 -0.176 0.172 0.306 0.5141 0.839 0.599 1.17 -0.37 0.178 0.0374 1.427 0.691 0.487 0.979 PRS_PLINK_0.00398107170553497 FALSE 427.11 Paroxysmal supraventricular tachycardia Both 260 1166 8 circulatory system red 1166, 260 291, 80 291, 53 291, 71 292, 56 -0.117 0.0731 0.111 0.9561 0.89 0.771 1.03 -0.451 0.199 0.0238 1.624 0.637 0.431 0.942 -0.184 0.195 0.345 0.4625 0.832 0.568 1.22 -0.433 0.202 0.0325 1.488 0.649 0.436 0.965 PRS_PLINK_0.00398107170553497 FALSE 427.12 Paroxysmal ventricular tachycardia Both 143 683 8 circulatory system red 683, 143 171, 35 171, 44 170, 33 171, 31 -0.0908 0.1 0.364 0.4385 0.913 0.751 1.11 0.0768 0.262 0.769 0.1139 1.08 0.646 1.8 -0.163 0.287 0.569 0.2446 0.85 0.484 1.49 -0.274 0.288 0.341 0.4674 0.76 0.432 1.34 PRS_PLINK_0.00398107170553497 FALSE 427.2 Atrial fibrillation and flutter Both 598 1505 8 circulatory system red 1505, 598 376, 146 376, 141 376, 174 376, 137 -0.0502 0.0554 0.365 0.4379 0.951 0.853 1.06 -0.149 0.156 0.338 0.4705 0.861 0.635 1.17 -0.00336 0.154 0.983 0.007626 0.997 0.737 1.35 -0.275 0.162 0.09 1.046 0.759 0.553 1.04 PRS_PLINK_0.00398107170553497 FALSE 427.21 Atrial fibrillation Both 582 1477 8 circulatory system red 1477, 582 369, 139 369, 131 369, 177 369, 135 -0.0327 0.0563 0.561 0.2511 0.968 0.867 1.08 -0.175 0.161 0.276 0.5592 0.839 0.612 1.15 0.063 0.156 0.686 0.1636 1.06 0.785 1.45 -0.227 0.165 0.17 0.7695 0.797 0.576 1.1 PRS_PLINK_0.00398107170553497 FALSE 427.22 Atrial flutter Both 222 714 8 circulatory system red 714, 222 178, 57 178, 44 178, 62 179, 59 -0.0171 0.086 0.842 0.07443 0.983 0.831 1.16 -0.262 0.24 0.275 0.5607 0.77 0.481 1.23 -0.0257 0.238 0.914 0.0391 0.975 0.612 1.55 -0.166 0.233 0.476 0.3221 0.847 0.537 1.34 PRS_PLINK_0.00398107170553497 FALSE 427.3 Other specified cardiac dysrhythmias Both 1316 2163 8 circulatory system red 2163, 1316 540, 346 541, 330 540, 339 541, 301 -0.0647 0.0379 0.0874 1.058 0.937 0.87 1.01 -0.187 0.106 0.0784 1.106 0.83 0.674 1.02 -0.0887 0.106 0.405 0.3927 0.915 0.743 1.13 -0.302 0.11 0.00612 2.213 0.739 0.596 0.917 PRS_PLINK_0.00398107170553497 FALSE 427.4 Cardiac arrest and ventricular fibrillation Both 49 352 8 circulatory system red 352, 49 88, 9 88, 12 88, 15 88, 13 0.243 0.169 0.15 0.8225 1.27 0.916 1.78 0.198 0.46 0.668 0.1755 1.22 0.494 3 0.622 0.458 0.175 0.757 1.86 0.758 4.57 0.289 0.451 0.522 0.2827 1.34 0.551 3.24 PRS_PLINK_0.00398107170553497 TRUE 427.41 Ventricular fibrillation and flutter Both 17 147 8 circulatory system red 147, 17 37, 2 37, 5 36, 6 37, 4 0.394 0.257 0.125 0.9034 1.48 0.897 2.45 0.846 0.787 0.282 0.5498 2.33 0.499 10.9 0.587 0.722 0.416 0.3806 1.8 0.437 7.4 0.318 0.784 0.685 0.1645 1.38 0.296 6.4 PRS_PLINK_0.00398107170553497 TRUE 427.42 Cardiac arrest Both 40 276 8 circulatory system red 276, 40 69, 7 69, 11 69, 13 69, 9 0.111 0.186 0.551 0.259 1.12 0.776 1.61 0.409 0.498 0.411 0.3862 1.51 0.568 3.99 0.695 0.514 0.176 0.7548 2 0.732 5.48 0.186 0.511 0.716 0.1448 1.2 0.442 3.28 PRS_PLINK_0.00398107170553497 TRUE 427.5 Arrhythmia (cardiac) NOS Both 1027 2157 8 circulatory system red 2157, 1027 539, 262 539, 265 539, 271 539, 229 -0.0482 0.0415 0.245 0.6108 0.953 0.879 1.03 -0.0716 0.115 0.533 0.2734 0.931 0.743 1.17 -0.00908 0.117 0.938 0.02771 0.991 0.788 1.25 -0.227 0.121 0.0614 1.212 0.797 0.628 1.01 PRS_PLINK_0.00398107170553497 FALSE 427.6 Premature beats Both 406 1395 8 circulatory system red 1395, 406 348, 102 349, 105 348, 114 349, 85 -0.0541 0.0605 0.371 0.4301 0.947 0.841 1.07 -0.0791 0.167 0.635 0.1972 0.924 0.667 1.28 0.0716 0.165 0.665 0.1771 1.07 0.777 1.49 -0.32 0.177 0.0702 1.154 0.726 0.513 1.03 PRS_PLINK_0.00398107170553497 FALSE 427.61 Supraventricular premature beats Both 133 534 8 circulatory system red 534, 133 133, 30 133, 39 133, 32 134, 32 -0.0423 0.0967 0.662 0.1794 0.959 0.793 1.16 0.169 0.286 0.555 0.2554 1.18 0.676 2.07 0.0576 0.293 0.844 0.0736 1.06 0.597 1.88 -0.155 0.296 0.599 0.2226 0.856 0.479 1.53 PRS_PLINK_0.00398107170553497 FALSE 427.7 Tachycardia NOS Both 737 2171 8 circulatory system red 2171, 737 542, 207 543, 172 542, 194 543, 164 -0.0894 0.0447 0.0454 1.343 0.914 0.838 0.998 -0.238 0.123 0.0541 1.267 0.788 0.619 1 -0.0539 0.123 0.662 0.1794 0.948 0.744 1.21 -0.275 0.128 0.0313 1.504 0.76 0.592 0.976 PRS_PLINK_0.00398107170553497 FALSE 427.8 Sinoatrial node dysfunction (Bradycardia) Both 155 513 8 circulatory system red 513, 155 129, 46 128, 22 128, 39 128, 48 0.00209 0.0997 0.983 0.00733 1 0.824 1.22 -0.684 0.295 0.0204 1.69 0.504 0.283 0.9 -0.22 0.261 0.4 0.3978 0.803 0.481 1.34 -0.0504 0.25 0.84 0.07553 0.951 0.582 1.55 PRS_PLINK_0.00398107170553497 FALSE 427.9 Palpitations Both 1121 2166 8 circulatory system red 2166, 1121 541, 305 541, 272 541, 307 542, 237 -0.0699 0.0393 0.0752 1.124 0.932 0.863 1.01 -0.155 0.108 0.148 0.8283 0.856 0.693 1.06 0.00206 0.109 0.985 0.006577 1 0.809 1.24 -0.296 0.113 0.00903 2.044 0.744 0.595 0.929 PRS_PLINK_0.00398107170553497 FALSE 428 Congestive heart failure; nonhypertensive Both 496 2126 8 circulatory system red 2126, 496 531, 119 531, 138 531, 129 532, 110 -0.0632 0.0543 0.245 0.6115 0.939 0.844 1.04 0.111 0.146 0.449 0.3477 1.12 0.839 1.49 -0.0353 0.15 0.814 0.08913 0.965 0.719 1.3 -0.228 0.158 0.149 0.8265 0.796 0.584 1.09 PRS_PLINK_0.00398107170553497 FALSE 428.1 Congestive heart failure (CHF) NOS Both 427 1978 8 circulatory system red 1978, 427 494, 102 494, 117 494, 114 495, 94 -0.0433 0.0577 0.453 0.344 0.958 0.855 1.07 0.114 0.156 0.462 0.3349 1.12 0.826 1.52 -0.00352 0.158 0.982 0.007789 0.996 0.731 1.36 -0.23 0.168 0.171 0.7682 0.794 0.572 1.1 PRS_PLINK_0.00398107170553497 FALSE 428.2 Heart failure NOS Both 394 1898 8 circulatory system red 1898, 394 474, 94 474, 112 474, 105 475, 83 -0.0622 0.06 0.3 0.5235 0.94 0.835 1.06 0.156 0.161 0.332 0.4793 1.17 0.853 1.6 -0.00623 0.165 0.97 0.01325 0.994 0.719 1.37 -0.209 0.174 0.23 0.6374 0.811 0.576 1.14 PRS_PLINK_0.00398107170553497 FALSE 428.3 Heart failure with reduced EF [Systolic or combined heart failure] Both 196 1090 8 circulatory system red 1090, 196 273, 50 272, 55 272, 54 273, 37 -0.147 0.0846 0.0825 1.083 0.863 0.732 1.02 0.0797 0.218 0.715 0.146 1.08 0.706 1.66 -0.0525 0.223 0.814 0.08937 0.949 0.612 1.47 -0.386 0.242 0.111 0.9544 0.68 0.423 1.09 PRS_PLINK_0.00398107170553497 FALSE 428.4 Heart failure with preserved EF [Diastolic heart failure] Both 210 1136 8 circulatory system red 1136, 210 284, 55 284, 51 284, 57 284, 47 -0.0811 0.0817 0.321 0.4942 0.922 0.786 1.08 -0.032 0.22 0.884 0.05356 0.968 0.63 1.49 -0.00656 0.216 0.976 0.01065 0.993 0.651 1.52 -0.188 0.228 0.409 0.3878 0.829 0.53 1.3 PRS_PLINK_0.00398107170553497 FALSE 429 Ill-defined descriptions and complications of heart disease Both 2081 3018 8 circulatory system red 3018, 2081 754, 546 754, 532 754, 517 755, 486 -0.0368 0.0303 0.225 0.6484 0.964 0.908 1.02 -0.0581 0.0834 0.486 0.3133 0.944 0.801 1.11 -0.101 0.0851 0.236 0.6262 0.904 0.765 1.07 -0.154 0.0869 0.0755 1.122 0.857 0.723 1.02 PRS_PLINK_0.00398107170553497 FALSE 429.1 Heart transplant/surgery Both 155 845 8 circulatory system red 845, 155 212, 40 211, 41 211, 35 211, 39 0.0201 0.0926 0.828 0.08181 1.02 0.851 1.22 -0.0238 0.248 0.923 0.03459 0.976 0.601 1.59 -0.102 0.257 0.692 0.1601 0.903 0.546 1.49 0.0544 0.264 0.837 0.07749 1.06 0.63 1.77 PRS_PLINK_0.00398107170553497 FALSE 429.2 Abnormal function study of cardiovascular system Both 994 2802 8 circulatory system red 2802, 994 700, 257 700, 259 700, 248 701, 230 -0.0425 0.0402 0.29 0.5381 0.958 0.886 1.04 -0.0197 0.109 0.856 0.06733 0.98 0.792 1.21 -0.125 0.112 0.263 0.5806 0.882 0.709 1.1 -0.191 0.115 0.0949 1.023 0.826 0.66 1.03 PRS_PLINK_0.00398107170553497 FALSE 429.3 Symptoms involving cardiovascular system Both 1659 3020 8 circulatory system red 3020, 1659 754, 438 755, 417 755, 412 755, 392 -0.0336 0.0321 0.296 0.528 0.967 0.908 1.03 -0.0731 0.089 0.411 0.3858 0.929 0.781 1.11 -0.0931 0.0905 0.304 0.5173 0.911 0.763 1.09 -0.144 0.0927 0.121 0.9186 0.866 0.722 1.04 PRS_PLINK_0.00398107170553497 FALSE 429.9 Cardiac complications, not elsewhere classified Both 88 474 8 circulatory system red 474, 88 119, 29 118, 25 118, 16 119, 18 -0.154 0.125 0.217 0.6629 0.857 0.671 1.1 -0.184 0.308 0.551 0.2591 0.832 0.455 1.52 -0.57 0.336 0.09 1.046 0.566 0.293 1.09 -0.429 0.333 0.198 0.7038 0.651 0.339 1.25 PRS_PLINK_0.00398107170553497 FALSE 430 Intracranial hemorrhage Both 101 790 8 circulatory system red 790, 101 198, 27 197, 18 197, 32 198, 24 -0.0107 0.11 0.923 0.03495 0.989 0.797 1.23 -0.43 0.314 0.171 0.7679 0.65 0.351 1.2 0.156 0.283 0.58 0.2366 1.17 0.672 2.03 -0.265 0.306 0.388 0.4116 0.768 0.421 1.4 PRS_PLINK_0.00398107170553497 FALSE 430.1 Subarachnoid hemorrhage Both 40 265 8 circulatory system red 265, 40 67, 10 66, 11 66, 12 66, 7 0.117 0.188 0.535 0.2716 1.12 0.777 1.63 0.138 0.487 0.777 0.1096 1.15 0.442 2.98 0.0459 0.491 0.925 0.03364 1.05 0.4 2.74 -0.56 0.532 0.293 0.533 0.571 0.201 1.62 PRS_PLINK_0.00398107170553497 TRUE 430.2 Intracerebral hemorrhage Both 50 377 8 circulatory system red 377, 50 95, 13 94, 9 94, 16 94, 12 -0.035 0.164 0.831 0.08031 0.966 0.7 1.33 -0.291 0.442 0.51 0.2925 0.747 0.314 1.78 0.013 0.409 0.975 0.01112 1.01 0.455 2.26 -0.332 0.445 0.455 0.3422 0.717 0.3 1.71 PRS_PLINK_0.00398107170553497 TRUE 430.3 Subdural hemorrhage Both 33 246 8 circulatory system red 246, 33 62, 8 61, 8 61, 8 62, 9 0.063 0.193 0.744 0.1284 1.07 0.729 1.56 0.0928 0.529 0.861 0.06519 1.1 0.389 3.09 0.0134 0.522 0.98 0.008967 1.01 0.364 2.82 -0.347 0.581 0.55 0.2597 0.707 0.226 2.21 PRS_PLINK_0.00398107170553497 TRUE 433 Cerebrovascular disease Both 702 3606 8 circulatory system red 3606, 702 901, 171 901, 166 901, 183 902, 182 0.0286 0.0437 0.513 0.2899 1.03 0.945 1.12 -0.0807 0.123 0.512 0.2907 0.922 0.725 1.17 -0.00884 0.122 0.942 0.0259 0.991 0.781 1.26 -0.0423 0.125 0.735 0.1337 0.959 0.75 1.22 PRS_PLINK_0.00398107170553497 FALSE 433.1 Occlusion and stenosis of precerebral arteries Both 277 1710 8 circulatory system red 1710, 277 428, 64 427, 71 427, 72 428, 70 0.00227 0.0671 0.973 0.01189 1 0.879 1.14 0.0344 0.188 0.855 0.06825 1.04 0.716 1.5 0.0566 0.191 0.767 0.1151 1.06 0.728 1.54 -0.0645 0.196 0.742 0.1295 0.938 0.638 1.38 PRS_PLINK_0.00398107170553497 FALSE 433.11 Occlusion of cerebral arteries, with cerebral infarction Both 31 277 8 circulatory system red 277, 31 70, 10 69, 5 69, 9 69, 7 -0.0777 0.183 0.671 0.1736 0.925 0.647 1.32 -0.746 0.548 0.173 0.7622 0.474 0.162 1.39 -0.225 0.501 0.653 0.1849 0.799 0.299 2.13 -0.628 0.527 0.233 0.6325 0.534 0.19 1.5 PRS_PLINK_0.00398107170553497 TRUE 433.12 Cerebral atherosclerosis Both 8 72 8 circulatory system red 72, 8 18, 3 18, 1 18, 1 18, 3 -0.21 0.351 0.549 0.2602 0.811 0.408 1.61 -0.825 0.98 0.4 0.3983 0.438 0.0643 2.99 -1.74 1.3 0.182 0.7404 0.176 0.0138 2.25 -0.67 1.08 0.534 0.2728 0.512 0.0621 4.22 PRS_PLINK_0.00398107170553497 TRUE 433.2 Occlusion of cerebral arteries Both 263 2347 8 circulatory system red 2347, 263 586, 69 587, 61 586, 68 587, 65 0.0032 0.0668 0.962 0.01696 1 0.88 1.14 -0.142 0.186 0.446 0.351 0.868 0.603 1.25 -0.0675 0.185 0.715 0.1458 0.935 0.651 1.34 -0.0621 0.189 0.743 0.1292 0.94 0.649 1.36 PRS_PLINK_0.00398107170553497 FALSE 433.21 Cerebral artery occlusion, with cerebral infarction Both 255 2267 8 circulatory system red 2267, 255 566, 66 567, 59 566, 68 567, 62 0.00257 0.0679 0.97 0.01333 1 0.878 1.15 -0.127 0.189 0.504 0.2978 0.881 0.608 1.28 -0.0393 0.187 0.834 0.07894 0.961 0.666 1.39 -0.0619 0.194 0.749 0.1254 0.94 0.643 1.37 PRS_PLINK_0.00398107170553497 FALSE 433.3 Cerebral ischemia Both 364 2507 8 circulatory system red 2507, 364 626, 88 627, 87 626, 98 627, 91 0.0485 0.0581 0.404 0.3936 1.05 0.937 1.18 -0.0253 0.164 0.877 0.05681 0.975 0.707 1.34 0.0623 0.163 0.702 0.1537 1.06 0.774 1.46 -0.0304 0.169 0.857 0.06713 0.97 0.697 1.35 PRS_PLINK_0.00398107170553497 FALSE 433.31 Transient cerebral ischemia Both 294 2279 8 circulatory system red 2279, 294 569, 76 570, 68 569, 78 570, 72 0.0286 0.0634 0.652 0.1856 1.03 0.909 1.17 -0.142 0.179 0.428 0.3687 0.867 0.61 1.23 -0.0184 0.177 0.917 0.03748 0.982 0.694 1.39 -0.12 0.185 0.516 0.2871 0.887 0.618 1.27 PRS_PLINK_0.00398107170553497 FALSE 433.5 Cerebral aneurysm Both 62 599 8 circulatory system red 599, 62 150, 14 150, 12 149, 20 150, 16 0.0824 0.137 0.548 0.2615 1.09 0.83 1.42 -0.325 0.4 0.416 0.3808 0.722 0.33 1.58 0.282 0.365 0.44 0.3561 1.33 0.648 2.71 -0.0322 0.381 0.933 0.03023 0.968 0.459 2.04 PRS_PLINK_0.00398107170553497 FALSE 433.6 Acute, but ill-defined cerebrovascular disease Both 67 499 8 circulatory system red 499, 67 125, 21 125, 18 124, 18 125, 10 -0.192 0.134 0.152 0.8193 0.826 0.635 1.07 -0.312 0.355 0.38 0.4204 0.732 0.365 1.47 -0.0653 0.354 0.854 0.06868 0.937 0.468 1.88 -0.783 0.416 0.0598 1.223 0.457 0.202 1.03 PRS_PLINK_0.00398107170553497 FALSE 433.8 Late effects of cerebrovascular disease Both 93 718 8 circulatory system red 718, 93 179, 31 179, 20 179, 20 180, 22 -0.171 0.109 0.118 0.9282 0.843 0.681 1.04 -0.447 0.304 0.141 0.8497 0.639 0.352 1.16 -0.5 0.311 0.108 0.9661 0.607 0.33 1.12 -0.582 0.312 0.062 1.208 0.559 0.303 1.03 PRS_PLINK_0.00398107170553497 FALSE 440 Atherosclerosis Both 352 1848 8 circulatory system red 1848, 352 462, 88 462, 97 462, 84 462, 83 -0.0252 0.0601 0.675 0.1707 0.975 0.867 1.1 0.0882 0.166 0.596 0.2247 1.09 0.788 1.51 -0.0818 0.172 0.635 0.1973 0.921 0.657 1.29 -0.0919 0.174 0.598 0.2231 0.912 0.648 1.28 PRS_PLINK_0.00398107170553497 FALSE 440.1 Atherosclerosis of renal artery Both 41 251 8 circulatory system red 251, 41 63, 9 63, 11 62, 9 63, 12 0.13 0.173 0.451 0.3463 1.14 0.812 1.6 0.327 0.497 0.51 0.2921 1.39 0.523 3.68 0.0986 0.533 0.853 0.06891 1.1 0.388 3.14 0.315 0.494 0.524 0.281 1.37 0.52 3.61 PRS_PLINK_0.00398107170553497 TRUE 440.2 Atherosclerosis of the extremities Both 200 1253 8 circulatory system red 1253, 200 314, 54 313, 55 313, 48 313, 43 -0.0764 0.0765 0.318 0.4976 0.926 0.798 1.08 0.00329 0.212 0.988 0.005406 1 0.662 1.52 -0.147 0.22 0.504 0.2973 0.863 0.561 1.33 -0.215 0.226 0.342 0.4666 0.806 0.518 1.26 PRS_PLINK_0.00398107170553497 FALSE 440.21 Atherosclerosis of native arteries of the extremities with ulceration or gangrene Both 31 241 8 circulatory system red 241, 31 60, 6 60, 12 60, 5 60, 8 -0.0115 0.201 0.954 0.02027 0.989 0.667 1.46 0.862 0.579 0.136 0.8663 2.37 0.762 7.36 -0.0494 0.66 0.94 0.0267 0.952 0.261 3.47 0.483 0.629 0.442 0.3541 1.62 0.472 5.57 PRS_PLINK_0.00398107170553497 TRUE 440.22 Atherosclerosis of native arteries of the extremities with intermittent claudication Both 161 930 8 circulatory system red 930, 161 233, 37 232, 45 232, 42 233, 37 -0.00173 0.0844 0.984 0.007184 0.998 0.846 1.18 0.206 0.242 0.395 0.4034 1.23 0.765 1.97 0.0939 0.247 0.704 0.1525 1.1 0.677 1.78 -0.0144 0.256 0.955 0.01996 0.986 0.597 1.63 PRS_PLINK_0.00398107170553497 FALSE 440.9 Atherosclerosis of aorta Both 124 715 8 circulatory system red 715, 124 179, 32 179, 37 178, 28 179, 27 -0.00643 0.0979 0.948 0.02337 0.994 0.82 1.2 0.0739 0.267 0.782 0.1071 1.08 0.639 1.82 -0.161 0.284 0.571 0.2431 0.852 0.489 1.48 -0.26 0.294 0.376 0.4245 0.771 0.434 1.37 PRS_PLINK_0.00398107170553497 FALSE 441 Vascular insufficiency of intestine Both 70 531 8 circulatory system red 531, 70 133, 20 133, 18 132, 16 133, 16 -0.119 0.14 0.396 0.4027 0.888 0.675 1.17 -0.169 0.355 0.634 0.1977 0.845 0.422 1.69 -0.363 0.375 0.332 0.4788 0.695 0.334 1.45 -0.239 0.37 0.518 0.2857 0.787 0.381 1.63 PRS_PLINK_0.00398107170553497 FALSE 441.1 Acute vascular insufficiency of intestine Both 40 253 8 circulatory system red 253, 40 64, 11 63, 12 63, 9 63, 8 -0.22 0.188 0.243 0.6148 0.803 0.555 1.16 -0.0468 0.505 0.926 0.03331 0.954 0.355 2.57 -0.126 0.486 0.796 0.09908 0.882 0.34 2.29 -0.64 0.524 0.222 0.6529 0.527 0.189 1.47 PRS_PLINK_0.00398107170553497 TRUE 441.2 Chronic vascular insufficiency of intestine Both 18 168 8 circulatory system red 168, 18 42, 5 42, 5 42, 4 42, 4 -0.0707 0.256 0.782 0.1068 0.932 0.564 1.54 -0.0117 0.665 0.986 0.00612 0.988 0.269 3.64 -0.519 1.01 0.607 0.217 0.595 0.0824 4.3 -0.0582 0.676 0.931 0.03091 0.943 0.251 3.55 PRS_PLINK_0.00398107170553497 TRUE 442 Other aneurysm Both 347 1899 8 circulatory system red 1899, 347 475, 82 475, 97 474, 89 475, 79 -0.0284 0.0617 0.645 0.1906 0.972 0.861 1.1 0.101 0.167 0.544 0.2641 1.11 0.798 1.54 -0.0516 0.173 0.766 0.1157 0.95 0.676 1.33 -0.19 0.181 0.295 0.5307 0.827 0.58 1.18 PRS_PLINK_0.00398107170553497 FALSE 442.1 Aortic aneurysm Both 262 1328 8 circulatory system red 1328, 262 332, 67 332, 69 332, 67 332, 59 -0.0174 0.0711 0.807 0.09326 0.983 0.855 1.13 -0.0134 0.191 0.944 0.02496 0.987 0.678 1.44 -0.0573 0.196 0.77 0.1134 0.944 0.643 1.39 -0.203 0.204 0.32 0.4954 0.816 0.547 1.22 PRS_PLINK_0.00398107170553497 FALSE 442.11 Abdominal aortic aneurysm Both 138 788 8 circulatory system red 788, 138 197, 32 197, 43 197, 28 197, 35 0.00259 0.0962 0.979 0.009428 1 0.83 1.21 0.246 0.258 0.34 0.469 1.28 0.772 2.12 -0.24 0.279 0.389 0.4097 0.787 0.456 1.36 0.0615 0.272 0.821 0.08573 1.06 0.624 1.81 PRS_PLINK_0.00398107170553497 FALSE 442.2 Aneurysm of iliac artery Both 17 116 8 circulatory system red 116, 17 29, 3 29, 7 29, 5 29, 2 0.126 0.286 0.66 0.1805 1.13 0.647 1.99 1.44 0.829 0.0823 1.085 4.22 0.832 21.4 0.696 0.769 0.365 0.4374 2.01 0.444 9.06 -0.124 0.846 0.884 0.05371 0.884 0.168 4.64 PRS_PLINK_0.00398107170553497 TRUE 442.3 Aneurysm of artery of lower extremity Both 16 117 8 circulatory system red 117, 16 30, 6 29, 5 29, 3 29, 2 -0.246 0.267 0.356 0.4488 0.782 0.463 1.32 -0.0416 0.674 0.951 0.02188 0.959 0.256 3.6 -0.719 0.74 0.331 0.4805 0.487 0.114 2.08 -0.639 0.854 0.454 0.343 0.528 0.0991 2.81 PRS_PLINK_0.00398107170553497 TRUE 442.4 Arterial dissection Both 23 130 8 circulatory system red 130, 23 33, 4 32, 10 32, 4 33, 5 -0.166 0.221 0.453 0.3441 0.847 0.55 1.31 1.11 0.723 0.124 0.9076 3.05 0.738 12.6 -0.224 0.777 0.774 0.1115 0.8 0.174 3.67 0.18 0.802 0.823 0.0848 1.2 0.248 5.77 PRS_PLINK_0.00398107170553497 TRUE 442.8 Aneurysm of other specified artery Both 59 382 8 circulatory system red 382, 59 96, 18 95, 19 95, 13 96, 9 -0.155 0.155 0.319 0.496 0.857 0.632 1.16 0.00558 0.356 0.987 0.005469 1.01 0.501 2.02 -0.326 0.385 0.397 0.4017 0.722 0.34 1.53 -0.501 0.431 0.244 0.6123 0.606 0.26 1.41 PRS_PLINK_0.00398107170553497 FALSE 443 Peripheral vascular disease Both 484 2557 8 circulatory system red 2557, 484 639, 116 639, 132 639, 127 639, 109 -0.00464 0.0516 0.928 0.03228 0.995 0.9 1.1 0.155 0.142 0.277 0.5579 1.17 0.883 1.54 0.0996 0.144 0.488 0.3112 1.1 0.833 1.46 -0.0732 0.151 0.627 0.203 0.929 0.692 1.25 PRS_PLINK_0.00398107170553497 FALSE 443.1 Raynaud's syndrome Both 199 959 8 circulatory system red 959, 199 240, 46 240, 43 239, 53 240, 57 0.111 0.0807 0.169 0.7716 1.12 0.954 1.31 -0.098 0.231 0.671 0.1732 0.907 0.577 1.43 0.237 0.229 0.3 0.523 1.27 0.809 1.99 0.175 0.226 0.439 0.358 1.19 0.765 1.86 PRS_PLINK_0.00398107170553497 FALSE 443.7 Peripheral angiopathy in diseases classified elsewhere Both 27 230 8 circulatory system red 230, 27 58, 8 57, 6 57, 9 58, 4 -0.114 0.222 0.609 0.2155 0.893 0.578 1.38 -0.22 0.567 0.698 0.1562 0.803 0.264 2.44 0.111 0.535 0.835 0.07831 1.12 0.392 3.19 -0.325 0.63 0.606 0.2178 0.722 0.21 2.48 PRS_PLINK_0.00398107170553497 TRUE 443.8 Other specified peripheral vascular diseases Both 392 2221 8 circulatory system red 2221, 392 555, 95 555, 110 555, 100 555, 87 -0.015 0.0565 0.791 0.1019 0.985 0.882 1.1 0.136 0.156 0.383 0.4164 1.15 0.844 1.55 0.0657 0.159 0.68 0.1677 1.07 0.782 1.46 -0.104 0.167 0.533 0.2737 0.901 0.65 1.25 PRS_PLINK_0.00398107170553497 FALSE 443.9 Peripheral vascular disease, unspecified Both 295 1798 8 circulatory system red 1798, 295 449, 72 449, 94 449, 66 450, 63 -0.0778 0.0655 0.235 0.6297 0.925 0.814 1.05 0.254 0.175 0.147 0.8323 1.29 0.915 1.82 -0.176 0.189 0.352 0.4538 0.838 0.578 1.21 -0.207 0.195 0.288 0.5405 0.813 0.555 1.19 PRS_PLINK_0.00398107170553497 FALSE 444 Arterial embolism and thrombosis Both 115 770 8 circulatory system red 770, 115 193, 34 192, 33 192, 21 193, 27 -0.135 0.101 0.18 0.7447 0.874 0.717 1.06 -0.131 0.268 0.625 0.2043 0.877 0.518 1.48 -0.541 0.3 0.0715 1.145 0.582 0.323 1.05 -0.193 0.285 0.498 0.3029 0.824 0.472 1.44 PRS_PLINK_0.00398107170553497 FALSE 444.1 Arterial embolism and thrombosis of lower extremity artery Both 43 277 8 circulatory system red 277, 43 70, 11 69, 16 69, 10 69, 6 -0.267 0.175 0.128 0.8944 0.766 0.544 1.08 0.0922 0.438 0.833 0.07932 1.1 0.465 2.59 -0.0174 0.481 0.971 0.0127 0.983 0.383 2.52 -0.688 0.571 0.228 0.6428 0.502 0.164 1.54 PRS_PLINK_0.00398107170553497 TRUE 444.2 Embolism and thrombosis of abdominal aorta Both 21 136 8 circulatory system red 136, 21 34, 7 34, 5 34, 7 34, 2 -0.208 0.214 0.331 0.48 0.813 0.535 1.24 -0.5 0.64 0.434 0.3622 0.606 0.173 2.13 -0.00394 0.563 0.994 0.002429 0.996 0.33 3 -0.942 0.792 0.234 0.6302 0.39 0.0825 1.84 PRS_PLINK_0.00398107170553497 TRUE 446 Polyarteritis nodosa and allied conditions Both 86 496 8 circulatory system red 496, 86 124, 21 124, 28 124, 10 124, 27 0.0648 0.119 0.585 0.2331 1.07 0.846 1.35 0.393 0.32 0.22 0.6586 1.48 0.791 2.78 -0.732 0.392 0.0616 1.21 0.481 0.223 1.04 0.231 0.327 0.479 0.3194 1.26 0.664 2.39 PRS_PLINK_0.00398107170553497 FALSE 446.4 Wegener's granulomatosis Both 18 118 8 circulatory system red 118, 18 30, 6 29, 6 29, 0 30, 6 -0.373 0.276 0.176 0.755 0.688 0.401 1.18 0.0196 0.67 0.977 0.01024 1.02 0.274 3.79 -2.7 1.32 0.0409 1.388 0.0675 0.00509 0.895 -0.158 0.648 0.808 0.09271 0.854 0.24 3.04 PRS_PLINK_0.00398107170553497 TRUE 446.5 Giant cell arteritis Both 23 86 8 circulatory system red 86, 23 22, 5 21, 8 21, 5 22, 5 0.153 0.228 0.501 0.3003 1.17 0.746 1.82 0.939 0.716 0.189 0.7227 2.56 0.629 10.4 0.16 0.714 0.823 0.08484 1.17 0.289 4.76 -0.368 0.761 0.629 0.2017 0.692 0.156 3.07 PRS_PLINK_0.00398107170553497 TRUE 446.9 Arteritis NOS Both 55 309 8 circulatory system red 309, 55 78, 15 77, 19 77, 4 77, 17 -0.095 0.155 0.539 0.2682 0.909 0.671 1.23 0.356 0.393 0.365 0.4375 1.43 0.661 3.08 -1.21 0.536 0.0239 1.622 0.298 0.104 0.852 0.115 0.402 0.776 0.1104 1.12 0.51 2.46 PRS_PLINK_0.00398107170553497 FALSE 447 Other disorders of arteries and arterioles Both 376 2081 8 circulatory system red 2081, 376 520, 94 520, 111 520, 91 520, 80 -0.0649 0.0587 0.268 0.5713 0.937 0.835 1.05 0.166 0.156 0.287 0.5424 1.18 0.87 1.6 -0.0629 0.167 0.707 0.1507 0.939 0.677 1.3 -0.234 0.174 0.179 0.7473 0.792 0.563 1.11 PRS_PLINK_0.00398107170553497 FALSE 447.1 Stricture of artery Both 70 476 8 circulatory system red 476, 70 119, 19 119, 22 119, 18 119, 11 -0.244 0.136 0.0731 1.136 0.784 0.6 1.02 0.112 0.341 0.743 0.1292 1.12 0.573 2.18 -0.242 0.364 0.505 0.2964 0.785 0.385 1.6 -0.572 0.407 0.16 0.7971 0.564 0.254 1.25 PRS_PLINK_0.00398107170553497 FALSE 447.7 Aortic ectasia Both 124 580 8 circulatory system red 580, 124 145, 37 145, 35 145, 31 145, 21 -0.111 0.101 0.271 0.5676 0.895 0.734 1.09 -0.00477 0.273 0.986 0.006097 0.995 0.583 1.7 -0.0844 0.283 0.766 0.116 0.919 0.528 1.6 -0.678 0.313 0.0306 1.515 0.508 0.275 0.938 PRS_PLINK_0.00398107170553497 FALSE 448 Disease of capillaries Both 338 1479 8 circulatory system red 1479, 338 370, 77 370, 86 369, 82 370, 93 0.0712 0.0616 0.248 0.6063 1.07 0.952 1.21 0.127 0.174 0.468 0.3299 1.14 0.806 1.6 0.0367 0.181 0.839 0.07637 1.04 0.728 1.48 0.261 0.178 0.141 0.8495 1.3 0.917 1.84 PRS_PLINK_0.00398107170553497 FALSE 450 Noninfectious disorders of lymphatic channels Both 323 2755 8 circulatory system red 2755, 323 688, 81 689, 78 688, 73 689, 91 0.0309 0.0604 0.609 0.2151 1.03 0.916 1.16 0.00611 0.168 0.971 0.01282 1.01 0.724 1.4 -0.0757 0.173 0.661 0.18 0.927 0.661 1.3 0.208 0.167 0.214 0.6705 1.23 0.887 1.71 PRS_PLINK_0.00398107170553497 FALSE 451 Phlebitis and thrombophlebitis Both 123 642 8 circulatory system red 642, 123 161, 34 160, 23 160, 30 161, 36 -0.0101 0.108 0.925 0.03383 0.99 0.801 1.22 -0.458 0.304 0.132 0.8807 0.633 0.349 1.15 -0.22 0.279 0.431 0.3654 0.803 0.465 1.39 0.101 0.284 0.723 0.1409 1.11 0.633 1.93 PRS_PLINK_0.00398107170553497 FALSE 451.2 Phlebitis and thrombophlebitis of lower extremities Both 42 223 8 circulatory system red 223, 42 56, 11 56, 10 55, 7 56, 14 0.0305 0.189 0.872 0.05968 1.03 0.712 1.49 0.00861 0.53 0.987 0.005661 1.01 0.357 2.85 -0.468 0.566 0.408 0.3895 0.626 0.207 1.9 0.428 0.482 0.374 0.4269 1.53 0.597 3.94 PRS_PLINK_0.00398107170553497 TRUE 452 Other venous embolism and thrombosis Both 520 2491 8 circulatory system red 2491, 520 622, 130 623, 128 622, 136 623, 126 -0.016 0.0502 0.75 0.1248 0.984 0.892 1.09 -0.0257 0.142 0.856 0.06759 0.975 0.738 1.29 -0.0167 0.14 0.905 0.04326 0.983 0.747 1.29 0.0454 0.146 0.756 0.1216 1.05 0.786 1.39 PRS_PLINK_0.00398107170553497 FALSE 452.1 Iatrogenic pulmonary embolism and infarction Both 30 234 8 circulatory system red 234, 30 59, 14 58, 5 58, 5 59, 6 -0.217 0.184 0.239 0.6216 0.805 0.561 1.16 -1.09 0.553 0.0492 1.308 0.337 0.114 0.996 -1.02 0.543 0.0613 1.213 0.362 0.125 1.05 -0.466 0.514 0.364 0.4391 0.627 0.229 1.72 PRS_PLINK_0.00398107170553497 TRUE 452.2 Deep vein thrombosis [DVT] Both 350 2250 8 circulatory system red 2250, 350 562, 90 562, 90 562, 84 563, 86 -0.0229 0.0592 0.699 0.1558 0.977 0.87 1.1 -0.00779 0.163 0.962 0.01693 0.992 0.721 1.36 -0.108 0.167 0.517 0.2869 0.897 0.647 1.24 0.0106 0.169 0.95 0.02216 1.01 0.725 1.41 PRS_PLINK_0.00398107170553497 FALSE 452.8 Postphlebitic syndrome Both 10 114 8 circulatory system red 114, 10 29, 3 28, 4 28, 2 29, 1 -0.345 0.353 0.328 0.4845 0.708 0.354 1.41 0.607 0.879 0.49 0.3097 1.83 0.328 10.3 -0.112 0.907 0.902 0.04472 0.894 0.151 5.29 -0.519 0.961 0.589 0.2299 0.595 0.0905 3.91 PRS_PLINK_0.00398107170553497 TRUE 453 Chronic venous hypertension Both 61 241 8 circulatory system red 241, 61 61, 17 60, 19 60, 11 60, 14 -0.0251 0.15 0.867 0.06204 0.975 0.727 1.31 0.125 0.385 0.746 0.1271 1.13 0.532 2.41 -0.33 0.435 0.449 0.3479 0.719 0.306 1.69 -0.413 0.448 0.357 0.4477 0.662 0.275 1.59 PRS_PLINK_0.00398107170553497 FALSE 454 Varicose veins Both 602 2233 8 circulatory system red 2233, 602 558, 159 558, 141 558, 133 558, 169 0.00648 0.0481 0.893 0.0492 1.01 0.916 1.11 -0.0964 0.134 0.471 0.3267 0.908 0.699 1.18 -0.22 0.137 0.108 0.9655 0.802 0.613 1.05 0.126 0.133 0.343 0.4647 1.13 0.874 1.47 PRS_PLINK_0.00398107170553497 FALSE 454.1 Varicose veins of lower extremity Both 585 2097 8 circulatory system red 2097, 585 524, 156 524, 138 524, 127 524, 164 -0.00309 0.0487 0.949 0.02255 0.997 0.906 1.1 -0.119 0.135 0.378 0.4225 0.888 0.681 1.16 -0.262 0.14 0.0613 1.213 0.77 0.585 1.01 0.083 0.135 0.539 0.2685 1.09 0.834 1.42 PRS_PLINK_0.00398107170553497 FALSE 454.11 Varicose veins of lower extremity, symptomtic Both 383 1513 8 circulatory system red 1513, 383 379, 100 378, 84 378, 89 378, 110 0.0166 0.0599 0.782 0.1068 1.02 0.904 1.14 -0.189 0.167 0.258 0.5883 0.828 0.596 1.15 -0.124 0.167 0.458 0.3392 0.884 0.637 1.23 0.119 0.163 0.465 0.3328 1.13 0.818 1.55 PRS_PLINK_0.00398107170553497 FALSE 455 Hemorrhoids Both 1391 2638 8 circulatory system red 2638, 1391 659, 333 659, 345 659, 355 660, 358 0.00748 0.0362 0.836 0.07766 1.01 0.939 1.08 -0.00828 0.1 0.934 0.0296 0.992 0.815 1.21 0.00608 0.101 0.952 0.02143 1.01 0.826 1.23 0.072 0.103 0.485 0.3143 1.07 0.878 1.32 PRS_PLINK_0.00398107170553497 FALSE 456 Chronic venous insufficiency [CVI] Both 657 2326 8 circulatory system red 2326, 657 581, 168 581, 146 581, 146 582, 197 0.0285 0.0461 0.537 0.2704 1.03 0.94 1.13 -0.144 0.131 0.274 0.5624 0.866 0.67 1.12 -0.197 0.133 0.14 0.8554 0.821 0.633 1.07 0.178 0.128 0.165 0.7829 1.19 0.929 1.54 PRS_PLINK_0.00398107170553497 FALSE 457 Encounter for long-term (current) use of anticoagulants, antithrombotics, aspirin Both 211 1156 8 circulatory system red 1156, 211 289, 52 289, 55 289, 51 289, 53 -0.0319 0.0775 0.681 0.1671 0.969 0.832 1.13 -0.0584 0.217 0.788 0.1036 0.943 0.617 1.44 -0.141 0.219 0.521 0.2829 0.869 0.565 1.34 -0.152 0.225 0.5 0.3012 0.859 0.552 1.34 PRS_PLINK_0.00398107170553497 FALSE 457.2 Encounter for long-term (current) use of antiplatelets/antithrombotics Both 26 198 8 circulatory system red 198, 26 50, 6 49, 8 49, 2 50, 10 -0.0497 0.22 0.821 0.08562 0.952 0.619 1.46 0.132 0.562 0.814 0.08926 1.14 0.379 3.43 -0.865 0.712 0.224 0.6493 0.421 0.104 1.7 0.395 0.579 0.494 0.306 1.48 0.478 4.61 PRS_PLINK_0.00398107170553497 TRUE 457.3 Encounter for long-term (current) use of aspirin Both 197 1120 8 circulatory system red 1120, 197 280, 47 280, 52 280, 49 280, 49 -0.0178 0.0797 0.824 0.08422 0.982 0.84 1.15 -0.0022 0.225 0.992 0.003404 0.998 0.642 1.55 -0.0767 0.226 0.734 0.1341 0.926 0.595 1.44 -0.132 0.235 0.574 0.2415 0.876 0.553 1.39 PRS_PLINK_0.00398107170553497 FALSE 458 Hypotension Both 707 3399 8 circulatory system red 3399, 707 849, 185 850, 180 849, 164 850, 178 -0.0205 0.0433 0.636 0.1963 0.98 0.9 1.07 -0.0757 0.118 0.522 0.2825 0.927 0.735 1.17 -0.184 0.122 0.133 0.8777 0.832 0.654 1.06 -0.0764 0.122 0.532 0.2743 0.926 0.729 1.18 PRS_PLINK_0.00398107170553497 FALSE 458.1 Orthostatic hypotension Both 229 1288 8 circulatory system red 1288, 229 322, 62 322, 52 322, 54 322, 61 -0.0146 0.0735 0.843 0.07421 0.986 0.853 1.14 -0.165 0.208 0.427 0.3692 0.848 0.565 1.27 -0.138 0.207 0.505 0.2964 0.871 0.58 1.31 -0.0347 0.204 0.865 0.06317 0.966 0.648 1.44 PRS_PLINK_0.00398107170553497 FALSE 458.2 Iatrogenic hypotension Both 141 1064 8 circulatory system red 1064, 141 266, 39 266, 36 266, 30 266, 36 0.00158 0.0944 0.987 0.005833 1 0.832 1.21 -0.0385 0.247 0.876 0.05742 0.962 0.593 1.56 -0.271 0.261 0.3 0.5229 0.763 0.457 1.27 0.0216 0.256 0.933 0.03032 1.02 0.619 1.69 PRS_PLINK_0.00398107170553497 FALSE 458.9 Hypotension NOS Both 638 3287 8 circulatory system red 3287, 638 821, 168 822, 165 821, 145 822, 160 -0.0221 0.0453 0.626 0.2034 0.978 0.895 1.07 -0.0435 0.123 0.723 0.1408 0.957 0.753 1.22 -0.2 0.128 0.119 0.925 0.818 0.636 1.05 -0.0787 0.128 0.538 0.2694 0.924 0.72 1.19 PRS_PLINK_0.00398107170553497 FALSE 459 Other disorders of circulatory system Both 978 3666 8 circulatory system red 3666, 978 916, 253 916, 233 916, 239 917, 253 0.00411 0.0381 0.914 0.03899 1 0.932 1.08 -0.125 0.105 0.234 0.63 0.882 0.718 1.08 -0.114 0.107 0.284 0.5467 0.892 0.724 1.1 -0.0176 0.107 0.869 0.06075 0.983 0.797 1.21 PRS_PLINK_0.00398107170553497 FALSE 459.1 Hemorrhage NOS Both 146 941 8 circulatory system red 941, 146 236, 40 235, 31 235, 37 235, 38 0.0368 0.0903 0.684 0.1651 1.04 0.869 1.24 -0.253 0.258 0.328 0.4848 0.777 0.469 1.29 -0.127 0.254 0.617 0.2099 0.881 0.535 1.45 -0.103 0.258 0.689 0.1619 0.902 0.544 1.5 PRS_PLINK_0.00398107170553497 FALSE 459.7 Blood vessel replaced Both 130 1183 8 circulatory system red 1183, 130 296, 37 296, 37 295, 26 296, 30 -0.0907 0.0988 0.359 0.4453 0.913 0.753 1.11 -0.0695 0.25 0.781 0.1075 0.933 0.572 1.52 -0.368 0.27 0.173 0.7631 0.692 0.408 1.17 -0.238 0.266 0.37 0.4314 0.788 0.468 1.33 PRS_PLINK_0.00398107170553497 FALSE 459.9 Circulatory disease NEC Both 804 3534 8 circulatory system red 3534, 804 883, 208 883, 191 883, 198 884, 207 0.0105 0.0413 0.799 0.09767 1.01 0.932 1.1 -0.127 0.115 0.268 0.5715 0.88 0.703 1.1 -0.112 0.116 0.333 0.477 0.894 0.713 1.12 -0.0232 0.117 0.842 0.07456 0.977 0.777 1.23 PRS_PLINK_0.00398107170553497 FALSE 464 Acute sinusitis Both 1295 2441 9 respiratory coral4 2441, 1295 611, 295 610, 323 610, 344 610, 332 0.0873 0.0361 0.0157 1.805 1.09 1.02 1.17 0.113 0.102 0.265 0.5764 1.12 0.918 1.37 0.201 0.102 0.0485 1.314 1.22 1 1.49 0.167 0.104 0.107 0.9699 1.18 0.964 1.45 PRS_PLINK_0.00398107170553497 FALSE 465 Acute upper respiratory infections of multiple or unspecified sites Both 2323 2584 9 respiratory coral4 2584, 2323 646, 578 646, 575 646, 577 646, 592 0.0452 0.0298 0.129 0.8889 1.05 0.987 1.11 0.033 0.0835 0.693 0.1595 1.03 0.878 1.22 0.0484 0.0846 0.567 0.2463 1.05 0.889 1.24 0.0634 0.0858 0.46 0.3376 1.07 0.901 1.26 PRS_PLINK_0.00398107170553497 FALSE 465.2 Acute pharyngitis Both 1289 2441 9 respiratory coral4 2441, 1289 611, 319 610, 330 610, 321 610, 319 0.0411 0.036 0.253 0.5972 1.04 0.971 1.12 0.0846 0.1 0.397 0.4008 1.09 0.895 1.32 0.0546 0.102 0.591 0.2281 1.06 0.865 1.29 0.0518 0.103 0.616 0.2106 1.05 0.86 1.29 PRS_PLINK_0.00398107170553497 FALSE 465.4 Acute laryngitis and tracheitis Both 106 393 9 respiratory coral4 393, 106 99, 33 98, 30 98, 18 98, 24 -0.075 0.114 0.51 0.2926 0.928 0.742 1.16 0.0322 0.309 0.917 0.03759 1.03 0.564 1.89 -0.392 0.343 0.254 0.5958 0.676 0.345 1.32 -0.246 0.335 0.462 0.3357 0.782 0.405 1.51 PRS_PLINK_0.00398107170553497 FALSE 470 Septal Deviations/Turbinate Hypertrophy Both 264 1232 9 respiratory coral4 1232, 264 308, 63 308, 61 308, 64 308, 76 0.17 0.0698 0.015 1.823 1.18 1.03 1.36 0.0358 0.202 0.86 0.0656 1.04 0.697 1.54 0.11 0.203 0.587 0.2316 1.12 0.75 1.66 0.195 0.196 0.321 0.494 1.22 0.827 1.79 PRS_PLINK_0.00398107170553497 FALSE 471 Nasal polyps Both 84 435 9 respiratory coral4 435, 84 109, 15 109, 20 108, 25 109, 24 0.107 0.118 0.367 0.4356 1.11 0.883 1.4 0.182 0.371 0.623 0.2057 1.2 0.58 2.48 0.434 0.364 0.233 0.6322 1.54 0.756 3.15 0.401 0.364 0.271 0.5677 1.49 0.731 3.05 PRS_PLINK_0.00398107170553497 FALSE 472 Chronic pharyngitis and nasopharyngitis Both 379 1537 9 respiratory coral4 1537, 379 385, 82 384, 110 384, 95 384, 92 0.0303 0.0613 0.62 0.2073 1.03 0.914 1.16 0.303 0.166 0.0686 1.164 1.35 0.977 1.88 0.134 0.172 0.435 0.3612 1.14 0.816 1.6 0.0868 0.178 0.625 0.2039 1.09 0.77 1.54 PRS_PLINK_0.00398107170553497 FALSE 473 Diseases of the larynx and vocal cords Both 485 1941 9 respiratory coral4 1941, 485 486, 117 485, 117 485, 132 485, 119 0.0387 0.0528 0.464 0.3338 1.04 0.937 1.15 0.0346 0.149 0.816 0.08835 1.04 0.773 1.39 0.17 0.148 0.252 0.5978 1.18 0.886 1.58 -0.00665 0.151 0.965 0.01552 0.993 0.739 1.34 PRS_PLINK_0.00398107170553497 FALSE 473.1 Chronic laryngitis Both 16 55 9 respiratory coral4 55, 16 14, 2 14, 4 13, 7 14, 3 0.201 0.34 0.554 0.2566 1.22 0.628 2.38 -0.0921 1.05 0.93 0.0315 0.912 0.117 7.13 1.05 0.998 0.291 0.5365 2.87 0.406 20.3 0.62 1.2 0.605 0.2184 1.86 0.178 19.4 PRS_PLINK_0.00398107170553497 TRUE 473.3 Paralysis/spasm of vocal cords or larynx Both 92 515 9 respiratory coral4 515, 92 129, 27 129, 22 128, 22 129, 21 -0.0351 0.118 0.765 0.1162 0.965 0.767 1.22 -0.189 0.31 0.541 0.2664 0.828 0.451 1.52 -0.0687 0.322 0.831 0.08036 0.934 0.497 1.76 -0.221 0.316 0.485 0.3147 0.802 0.432 1.49 PRS_PLINK_0.00398107170553497 FALSE 473.4 Voice disturbance Both 379 1721 9 respiratory coral4 1721, 379 431, 93 430, 92 430, 97 430, 97 0.041 0.0582 0.482 0.3172 1.04 0.929 1.17 0.0327 0.165 0.842 0.07445 1.03 0.748 1.43 0.0705 0.166 0.671 0.1734 1.07 0.775 1.49 0.036 0.166 0.828 0.08193 1.04 0.749 1.43 PRS_PLINK_0.00398107170553497 FALSE 474 Acute and chronic tonsillitis Both 135 615 9 respiratory coral4 615, 135 154, 35 154, 30 153, 34 154, 36 0.0878 0.0963 0.361 0.4419 1.09 0.904 1.32 -0.164 0.276 0.552 0.2581 0.849 0.494 1.46 0.0149 0.274 0.957 0.01922 1.01 0.593 1.74 0.0359 0.273 0.895 0.04814 1.04 0.608 1.77 PRS_PLINK_0.00398107170553497 FALSE 474.1 Acute tonsillitis Both 58 222 9 respiratory coral4 222, 58 56, 14 55, 12 55, 15 56, 17 0.189 0.157 0.228 0.6429 1.21 0.888 1.64 -0.0817 0.452 0.857 0.0672 0.922 0.38 2.24 0.135 0.438 0.757 0.1209 1.15 0.486 2.7 0.394 0.459 0.391 0.408 1.48 0.603 3.65 PRS_PLINK_0.00398107170553497 FALSE 474.2 Chronic tonsillitis and adenoiditis Both 95 471 9 respiratory coral4 471, 95 118, 25 118, 21 117, 25 118, 24 0.107 0.113 0.344 0.4636 1.11 0.892 1.39 -0.312 0.337 0.355 0.4504 0.732 0.378 1.42 0.0913 0.322 0.777 0.1097 1.1 0.583 2.06 -0.107 0.325 0.743 0.129 0.899 0.475 1.7 PRS_PLINK_0.00398107170553497 FALSE 475 Chronic sinusitis Both 894 2139 9 respiratory coral4 2139, 894 535, 207 535, 226 534, 229 535, 232 0.0942 0.0415 0.0231 1.636 1.1 1.01 1.19 0.112 0.117 0.338 0.471 1.12 0.89 1.41 0.173 0.118 0.143 0.8452 1.19 0.943 1.5 0.138 0.119 0.248 0.6062 1.15 0.909 1.45 PRS_PLINK_0.00398107170553497 FALSE 475.9 Postnasal drip Both 226 859 9 respiratory coral4 859, 226 215, 51 215, 49 214, 46 215, 80 0.175 0.0801 0.0289 1.538 1.19 1.02 1.39 -0.0502 0.225 0.824 0.08422 0.951 0.612 1.48 -0.104 0.232 0.654 0.1844 0.901 0.572 1.42 0.418 0.209 0.0461 1.336 1.52 1.01 2.29 PRS_PLINK_0.00398107170553497 FALSE 476 Allergic rhinitis Both 2323 2158 9 respiratory coral4 2158, 2323 540, 559 539, 609 539, 552 540, 602 0.0725 0.0313 0.0204 1.691 1.08 1.01 1.14 0.114 0.0876 0.192 0.7168 1.12 0.944 1.33 0.0535 0.0892 0.549 0.2606 1.05 0.886 1.26 0.139 0.0895 0.119 0.9235 1.15 0.965 1.37 PRS_PLINK_0.00398107170553497 FALSE 477 Epistaxis or throat hemorrhage Both 195 897 9 respiratory coral4 897, 195 225, 46 224, 51 224, 47 224, 51 0.0296 0.0797 0.71 0.1486 1.03 0.881 1.2 0.133 0.226 0.557 0.2543 1.14 0.734 1.78 -0.0467 0.231 0.84 0.07593 0.954 0.607 1.5 0.0585 0.231 0.8 0.09668 1.06 0.674 1.67 PRS_PLINK_0.00398107170553497 FALSE 478 Throat pain Both 66 328 9 respiratory coral4 328, 66 82, 19 82, 19 82, 17 82, 11 -0.201 0.143 0.158 0.8011 0.818 0.618 1.08 0.0506 0.373 0.892 0.04957 1.05 0.506 2.18 -0.278 0.398 0.484 0.3152 0.757 0.347 1.65 -0.902 0.444 0.042 1.377 0.406 0.17 0.968 PRS_PLINK_0.00398107170553497 FALSE 479 Other upper respiratory disease Both 944 2149 9 respiratory coral4 2149, 944 538, 197 537, 255 537, 236 537, 255 0.155 0.041 0.000156 3.808 1.17 1.08 1.27 0.286 0.116 0.0138 1.862 1.33 1.06 1.67 0.234 0.119 0.0492 1.308 1.26 1 1.6 0.275 0.118 0.0204 1.691 1.32 1.04 1.66 PRS_PLINK_0.00398107170553497 FALSE 480 Pneumonia Both 903 3545 9 respiratory coral4 3545, 903 886, 215 886, 270 886, 218 886, 200 -0.0171 0.0387 0.659 0.181 0.983 0.911 1.06 0.22 0.105 0.0369 1.433 1.25 1.01 1.53 0.0415 0.111 0.709 0.1494 1.04 0.838 1.3 -0.0538 0.115 0.639 0.1944 0.948 0.757 1.19 PRS_PLINK_0.00398107170553497 FALSE 480.1 Bacterial pneumonia Both 207 1079 9 respiratory coral4 1079, 207 270, 48 270, 59 269, 55 270, 45 0.0155 0.0794 0.845 0.07308 1.02 0.869 1.19 0.205 0.214 0.338 0.4714 1.23 0.807 1.87 0.099 0.219 0.651 0.1861 1.1 0.719 1.7 -0.0863 0.232 0.71 0.1488 0.917 0.582 1.45 PRS_PLINK_0.00398107170553497 FALSE 480.11 Pneumococcal pneumonia Both 117 532 9 respiratory coral4 532, 117 133, 29 133, 31 133, 33 133, 24 0.0194 0.105 0.853 0.0689 1.02 0.83 1.25 0.0746 0.29 0.797 0.09867 1.08 0.611 1.9 0.0724 0.29 0.803 0.09548 1.08 0.609 1.9 -0.287 0.315 0.362 0.4417 0.75 0.404 1.39 PRS_PLINK_0.00398107170553497 FALSE 480.12 Pseudomonal pneumonia Both 20 140 9 respiratory coral4 140, 20 35, 5 35, 6 35, 6 35, 3 -0.0521 0.237 0.826 0.083 0.949 0.597 1.51 0.27 0.642 0.674 0.1714 1.31 0.372 4.61 -0.106 0.667 0.873 0.05887 0.899 0.243 3.33 -0.592 0.777 0.446 0.3507 0.553 0.121 2.54 PRS_PLINK_0.00398107170553497 TRUE 480.13 MRSA pneumonia Both 8 115 9 respiratory coral4 115, 8 29, 1 29, 3 28, 1 29, 3 0.14 0.375 0.708 0.1499 1.15 0.552 2.4 0.693 0.986 0.482 0.3168 2 0.289 13.8 2.43 1.83 0.184 0.7359 11.4 0.315 411 0.884 0.878 0.314 0.503 2.42 0.433 13.5 PRS_PLINK_0.00398107170553497 TRUE 480.2 Viral pneumonia Both 40 184 9 respiratory coral4 184, 40 46, 10 46, 16 46, 4 46, 10 -0.231 0.18 0.198 0.7031 0.794 0.558 1.13 0.367 0.475 0.44 0.3566 1.44 0.569 3.66 -1.17 0.638 0.0663 1.179 0.31 0.0889 1.08 -0.241 0.527 0.647 0.1888 0.786 0.28 2.21 PRS_PLINK_0.00398107170553497 TRUE 480.3 Pneumonia due to fungus (mycoses) Both 33 129 9 respiratory coral4 129, 33 33, 10 32, 10 32, 9 32, 4 -0.159 0.211 0.452 0.3447 0.853 0.564 1.29 0.0021 0.534 0.997 0.001367 1 0.352 2.85 -0.198 0.556 0.721 0.1419 0.82 0.276 2.44 -0.782 0.648 0.227 0.6436 0.457 0.129 1.63 PRS_PLINK_0.00398107170553497 TRUE 480.5 Bronchopneumonia and lung abscess Both 14 130 9 respiratory coral4 130, 14 33, 6 32, 1 32, 5 33, 2 -0.0946 0.272 0.728 0.1376 0.91 0.533 1.55 -1.29 0.869 0.137 0.8639 0.275 0.05 1.51 0.0265 0.681 0.969 0.01367 1.03 0.27 3.9 -1.34 0.847 0.114 0.9448 0.262 0.0498 1.38 PRS_PLINK_0.00398107170553497 TRUE 481 Influenza Both 312 1562 9 respiratory coral4 1562, 312 391, 72 390, 69 390, 95 391, 76 0.0495 0.0655 0.449 0.3473 1.05 0.924 1.19 -0.0141 0.186 0.94 0.027 0.986 0.684 1.42 0.329 0.177 0.0628 1.202 1.39 0.983 1.97 0.127 0.184 0.491 0.3087 1.14 0.791 1.63 PRS_PLINK_0.00398107170553497 FALSE 483 Acute bronchitis and bronchiolitis Both 810 3226 9 respiratory coral4 3226, 810 806, 204 806, 219 806, 206 807, 181 0.0147 0.0403 0.715 0.1457 1.01 0.938 1.1 0.0939 0.111 0.396 0.4022 1.1 0.884 1.36 0.0362 0.114 0.75 0.1249 1.04 0.83 1.3 -0.0755 0.118 0.521 0.2832 0.927 0.737 1.17 PRS_PLINK_0.00398107170553497 FALSE 495 Asthma Both 1252 3425 9 respiratory coral4 3425, 1252 857, 311 856, 323 856, 334 856, 284 0.0204 0.0341 0.55 0.26 1.02 0.955 1.09 0.0701 0.0944 0.457 0.3397 1.07 0.892 1.29 0.134 0.0954 0.159 0.7976 1.14 0.949 1.38 -0.00825 0.0992 0.934 0.02979 0.992 0.817 1.2 PRS_PLINK_0.00398107170553497 FALSE 495.1 Chronic obstructive asthma Both 72 507 9 respiratory coral4 507, 72 127, 24 127, 15 126, 17 127, 16 -0.131 0.13 0.312 0.5064 0.877 0.68 1.13 -0.552 0.358 0.124 0.9071 0.576 0.285 1.16 -0.486 0.35 0.165 0.7836 0.615 0.31 1.22 -0.361 0.356 0.311 0.5074 0.697 0.347 1.4 PRS_PLINK_0.00398107170553497 FALSE 495.11 Chronic obstructive asthma with exacerbation Both 20 132 9 respiratory coral4 132, 20 33, 3 33, 7 33, 6 33, 4 0.0937 0.268 0.726 0.1389 1.1 0.65 1.86 0.349 0.734 0.634 0.1978 1.42 0.336 5.97 1.29 0.905 0.154 0.8116 3.63 0.616 21.4 0.5 0.819 0.542 0.2662 1.65 0.331 8.21 PRS_PLINK_0.00398107170553497 TRUE 495.2 Asthma with exacerbation Both 373 2074 9 respiratory coral4 2074, 373 519, 80 518, 92 518, 104 519, 97 0.108 0.0575 0.0599 1.223 1.11 0.996 1.25 0.133 0.166 0.422 0.3742 1.14 0.825 1.58 0.24 0.165 0.146 0.8358 1.27 0.92 1.76 0.182 0.168 0.279 0.5551 1.2 0.863 1.67 PRS_PLINK_0.00398107170553497 FALSE 496 Chronic airway obstruction Both 556 2919 9 respiratory coral4 2919, 556 730, 152 730, 150 729, 128 730, 125 -0.0751 0.0484 0.12 0.92 0.928 0.844 1.02 -0.0603 0.13 0.643 0.1919 0.941 0.729 1.21 -0.233 0.137 0.0884 1.054 0.792 0.606 1.04 -0.241 0.139 0.0817 1.088 0.786 0.599 1.03 PRS_PLINK_0.00398107170553497 FALSE 496.1 Emphysema Both 232 1816 9 respiratory coral4 1816, 232 454, 70 454, 63 454, 54 454, 45 -0.133 0.0708 0.0596 1.225 0.875 0.762 1.01 -0.114 0.187 0.541 0.2665 0.892 0.618 1.29 -0.28 0.197 0.156 0.8071 0.756 0.514 1.11 -0.472 0.207 0.0227 1.644 0.624 0.416 0.936 PRS_PLINK_0.00398107170553497 FALSE 496.2 Chronic bronchitis Both 425 2733 9 respiratory coral4 2733, 425 684, 124 683, 111 683, 94 683, 95 -0.0993 0.054 0.066 1.18 0.906 0.815 1.01 -0.142 0.144 0.324 0.49 0.868 0.654 1.15 -0.331 0.152 0.0293 1.534 0.718 0.533 0.967 -0.297 0.153 0.0526 1.279 0.743 0.551 1 PRS_PLINK_0.00398107170553497 FALSE 496.21 Obstructive chronic bronchitis Both 389 2604 9 respiratory coral4 2604, 389 651, 113 651, 103 651, 84 651, 88 -0.0871 0.0561 0.12 0.9195 0.917 0.821 1.02 -0.129 0.15 0.39 0.4093 0.879 0.655 1.18 -0.348 0.16 0.0294 1.532 0.706 0.517 0.966 -0.257 0.159 0.106 0.9755 0.773 0.567 1.06 PRS_PLINK_0.00398107170553497 FALSE 496.3 Bronchiectasis Both 108 619 9 respiratory coral4 619, 108 155, 28 155, 30 154, 25 155, 25 0.103 0.112 0.358 0.4457 1.11 0.89 1.38 0.0778 0.291 0.789 0.1029 1.08 0.611 1.91 0.00833 0.304 0.978 0.009594 1.01 0.555 1.83 -0.153 0.304 0.615 0.2111 0.858 0.473 1.56 PRS_PLINK_0.00398107170553497 FALSE 497 Bronchitis Both 457 2394 9 respiratory coral4 2394, 457 599, 121 598, 118 598, 113 599, 105 -0.0576 0.0525 0.273 0.5646 0.944 0.852 1.05 -0.009 0.143 0.95 0.02229 0.991 0.748 1.31 -0.103 0.148 0.487 0.3121 0.902 0.675 1.21 -0.14 0.151 0.354 0.4506 0.869 0.647 1.17 PRS_PLINK_0.00398107170553497 FALSE 498 Acute bronchospasm Both 114 614 9 respiratory coral4 614, 114 154, 18 153, 32 153, 33 154, 31 0.104 0.103 0.313 0.5045 1.11 0.907 1.36 0.545 0.322 0.0908 1.042 1.72 0.917 3.24 0.588 0.316 0.0629 1.201 1.8 0.969 3.35 0.474 0.325 0.145 0.8392 1.61 0.849 3.04 PRS_PLINK_0.00398107170553497 FALSE 499 Cystic fibrosis Both 39 232 9 respiratory coral4 232, 39 58, 11 58, 7 58, 10 58, 11 0.141 0.194 0.467 0.3305 1.15 0.787 1.69 -0.745 0.576 0.196 0.7084 0.475 0.153 1.47 -0.0105 0.537 0.984 0.006821 0.99 0.345 2.84 0.156 0.524 0.766 0.1156 1.17 0.418 3.26 PRS_PLINK_0.00398107170553497 TRUE 500 Lung disease due to external agents Both 72 585 9 respiratory coral4 585, 72 147, 18 146, 16 146, 21 146, 17 0.0697 0.127 0.584 0.2338 1.07 0.836 1.38 -0.0223 0.36 0.951 0.02196 0.978 0.483 1.98 0.0824 0.342 0.81 0.09161 1.09 0.555 2.12 -0.0452 0.36 0.9 0.04567 0.956 0.472 1.94 PRS_PLINK_0.00398107170553497 FALSE 500.1 Extrinsic allergic alveolitis Both 22 137 9 respiratory coral4 137, 22 35, 6 34, 3 34, 8 34, 5 0.102 0.246 0.678 0.1685 1.11 0.683 1.8 -0.9 0.723 0.214 0.6704 0.407 0.0985 1.68 0.122 0.612 0.841 0.075 1.13 0.341 3.75 -0.109 0.679 0.872 0.05933 0.897 0.237 3.39 PRS_PLINK_0.00398107170553497 TRUE 500.2 Pneumoconiosis Both 8 56 9 respiratory coral4 56, 8 14, 3 14, 3 14, 2 14, 0 -0.506 0.405 0.212 0.6743 0.603 0.273 1.33 0.449 0.97 0.644 0.1912 1.57 0.234 10.5 -0.422 1.1 0.701 0.1542 0.656 0.0758 5.67 -1.58 1.4 0.256 0.5913 0.205 0.0133 3.16 PRS_PLINK_0.00398107170553497 TRUE 501 Pneumonitis due to inhalation of food or vomitus Both 76 559 9 respiratory coral4 559, 76 140, 17 140, 20 139, 22 140, 17 0.0051 0.122 0.967 0.01476 1.01 0.792 1.28 0.167 0.354 0.637 0.1956 1.18 0.591 2.36 0.24 0.347 0.489 0.3106 1.27 0.644 2.51 -0.138 0.368 0.707 0.1503 0.871 0.423 1.79 PRS_PLINK_0.00398107170553497 FALSE 502 Postinflammatory pulmonary fibrosis Both 125 848 9 respiratory coral4 848, 125 212, 36 212, 30 212, 28 212, 31 0.00108 0.0986 0.991 0.003819 1 0.825 1.21 -0.178 0.264 0.501 0.3003 0.837 0.499 1.4 -0.153 0.272 0.574 0.2414 0.858 0.504 1.46 -0.166 0.269 0.538 0.2692 0.847 0.5 1.44 PRS_PLINK_0.00398107170553497 FALSE 503 Pulmonary congestion and hypostasis Both 104 824 9 respiratory coral4 824, 104 206, 30 206, 31 206, 22 206, 21 -0.127 0.107 0.235 0.6293 0.88 0.714 1.09 -0.000131 0.274 1 0.0001663 1 0.585 1.71 -0.443 0.303 0.144 0.8418 0.642 0.354 1.16 -0.435 0.308 0.159 0.7993 0.647 0.354 1.19 PRS_PLINK_0.00398107170553497 FALSE 504 Other alveolar and parietoalveolar pneumonopathy Both 103 673 9 respiratory coral4 673, 103 169, 25 168, 26 168, 28 168, 24 0.00931 0.11 0.932 0.03047 1.01 0.814 1.25 0.0862 0.298 0.772 0.1123 1.09 0.608 1.95 0.174 0.303 0.564 0.2485 1.19 0.658 2.15 -0.107 0.307 0.726 0.1389 0.898 0.492 1.64 PRS_PLINK_0.00398107170553497 FALSE 504.1 Idiopathic fibrosing alveolitis Both 54 341 9 respiratory coral4 341, 54 86, 14 85, 11 85, 16 85, 13 -0.00606 0.154 0.969 0.01384 0.994 0.735 1.34 -0.209 0.413 0.613 0.2123 0.812 0.361 1.82 0.0588 0.405 0.885 0.05326 1.06 0.48 2.35 -0.203 0.42 0.629 0.2014 0.816 0.358 1.86 PRS_PLINK_0.00398107170553497 FALSE 505 Other pulmonary inflamation or edema Both 209 1606 9 respiratory coral4 1606, 209 402, 44 401, 57 401, 54 402, 54 0.0743 0.0752 0.323 0.4905 1.08 0.93 1.25 0.272 0.213 0.202 0.6949 1.31 0.864 1.99 0.175 0.217 0.421 0.3757 1.19 0.778 1.82 0.16 0.222 0.47 0.3281 1.17 0.76 1.81 PRS_PLINK_0.00398107170553497 FALSE 506 Empyema and pneumothorax Both 304 2372 9 respiratory coral4 2372, 304 593, 69 593, 87 593, 79 593, 68 -0.11 0.0628 0.0793 1.101 0.896 0.792 1.01 0.175 0.173 0.309 0.5096 1.19 0.85 1.67 0.0476 0.178 0.789 0.103 1.05 0.74 1.49 -0.171 0.187 0.359 0.4448 0.842 0.584 1.22 PRS_PLINK_0.00398107170553497 FALSE 507 Pleurisy; pleural effusion Both 361 2708 9 respiratory coral4 2708, 361 677, 91 677, 98 677, 89 677, 83 -0.0461 0.0571 0.42 0.3768 0.955 0.854 1.07 0.0779 0.157 0.619 0.2084 1.08 0.795 1.47 -0.00928 0.162 0.954 0.02031 0.991 0.721 1.36 -0.0791 0.167 0.635 0.1973 0.924 0.667 1.28 PRS_PLINK_0.00398107170553497 FALSE 508 Pulmonary collapse; interstitial and compensatory emphysema Both 259 2311 9 respiratory coral4 2311, 259 578, 67 578, 69 577, 61 578, 62 -0.059 0.0666 0.375 0.4257 0.943 0.827 1.07 0.0179 0.182 0.921 0.03552 1.02 0.713 1.45 -0.104 0.188 0.58 0.2368 0.901 0.623 1.3 -0.137 0.19 0.47 0.3283 0.872 0.601 1.26 PRS_PLINK_0.00398107170553497 FALSE 509 Respiratory failure, insufficiency, arrest Both 462 3044 9 respiratory coral4 3044, 462 761, 113 761, 126 761, 115 761, 108 -0.0346 0.0514 0.501 0.3004 0.966 0.873 1.07 0.0441 0.142 0.755 0.1218 1.05 0.792 1.38 -0.0365 0.146 0.803 0.09521 0.964 0.724 1.28 -0.143 0.151 0.345 0.4616 0.867 0.645 1.17 PRS_PLINK_0.00398107170553497 FALSE 509.1 Respiratory failure Both 236 1873 9 respiratory coral4 1873, 236 469, 58 468, 65 468, 63 468, 50 -0.00287 0.07 0.967 0.01442 0.997 0.869 1.14 0.119 0.192 0.536 0.2709 1.13 0.773 1.64 0.085 0.197 0.666 0.1763 1.09 0.74 1.6 -0.154 0.21 0.464 0.3338 0.858 0.569 1.29 PRS_PLINK_0.00398107170553497 FALSE 509.2 Respiratory insufficiency Both 146 1056 9 respiratory coral4 1056, 146 264, 40 264, 40 264, 31 264, 35 -0.0139 0.0894 0.876 0.05743 0.986 0.828 1.17 0.0432 0.242 0.858 0.06644 1.04 0.65 1.68 -0.247 0.261 0.344 0.4634 0.781 0.469 1.3 -0.211 0.258 0.414 0.383 0.81 0.489 1.34 PRS_PLINK_0.00398107170553497 FALSE 509.3 Pulmonary insufficiency or respiratory failure following trauma and surgery Both 199 1430 9 respiratory coral4 1430, 199 358, 46 357, 59 357, 48 358, 46 0.0213 0.0771 0.783 0.1063 1.02 0.878 1.19 0.236 0.213 0.267 0.5732 1.27 0.835 1.92 -0.00336 0.221 0.988 0.005303 0.997 0.646 1.54 -0.0817 0.228 0.72 0.1424 0.922 0.589 1.44 PRS_PLINK_0.00398107170553497 FALSE 509.8 Dependence on respirator [Ventilator] or supplemental oxygen Both 195 1736 9 respiratory coral4 1736, 195 434, 49 434, 63 434, 50 434, 33 -0.119 0.0771 0.124 0.9074 0.888 0.764 1.03 0.234 0.201 0.245 0.6105 1.26 0.852 1.87 -0.0207 0.216 0.924 0.03451 0.98 0.642 1.49 -0.43 0.24 0.0726 1.139 0.65 0.407 1.04 PRS_PLINK_0.00398107170553497 FALSE 510 Other diseases of lung Both 896 3832 9 respiratory coral4 3832, 896 957, 221 958, 239 958, 213 958, 223 -0.0265 0.0388 0.494 0.3059 0.974 0.903 1.05 0.0572 0.106 0.59 0.2291 1.06 0.86 1.3 -0.0516 0.11 0.639 0.1943 0.95 0.765 1.18 -0.0187 0.111 0.866 0.06257 0.981 0.79 1.22 PRS_PLINK_0.00398107170553497 FALSE 510.2 Lung transplant Both 41 141 9 respiratory coral4 141, 41 36, 12 35, 12 35, 8 35, 9 -0.017 0.194 0.93 0.03142 0.983 0.672 1.44 -0.00909 0.5 0.985 0.006351 0.991 0.372 2.64 -0.408 0.588 0.488 0.312 0.665 0.21 2.1 -0.399 0.554 0.471 0.3265 0.671 0.226 1.99 PRS_PLINK_0.00398107170553497 TRUE 512 Other symptoms of respiratory system Both 3144 2087 9 respiratory coral4 2087, 3144 522, 702 522, 748 521, 840 522, 853 0.0957 0.0299 0.00139 2.858 1.1 1.04 1.17 0.0525 0.0846 0.535 0.272 1.05 0.893 1.24 0.163 0.0848 0.0547 1.262 1.18 0.997 1.39 0.185 0.0862 0.0315 1.502 1.2 1.02 1.43 PRS_PLINK_0.00398107170553497 FALSE 512.1 Wheezing Both 292 1192 9 respiratory coral4 1192, 292 298, 70 298, 68 298, 85 298, 69 0.0537 0.0675 0.426 0.3704 1.06 0.924 1.2 0.00236 0.195 0.99 0.004214 1 0.684 1.47 0.188 0.187 0.315 0.5013 1.21 0.836 1.74 0.0191 0.196 0.922 0.03505 1.02 0.694 1.5 PRS_PLINK_0.00398107170553497 FALSE 512.2 Painful respiration Both 499 1744 9 respiratory coral4 1744, 499 436, 126 436, 96 436, 135 436, 142 0.0835 0.0536 0.12 0.9223 1.09 0.979 1.21 -0.282 0.156 0.0703 1.153 0.754 0.556 1.02 0.0259 0.147 0.86 0.06535 1.03 0.769 1.37 0.09 0.148 0.543 0.2654 1.09 0.819 1.46 PRS_PLINK_0.00398107170553497 FALSE 512.3 Abnormal chest sounds Both 48 193 9 respiratory coral4 193, 48 49, 8 48, 15 48, 11 48, 14 0.106 0.179 0.554 0.2568 1.11 0.783 1.58 0.639 0.523 0.221 0.6551 1.89 0.68 5.28 0.0207 0.54 0.969 0.01349 1.02 0.354 2.94 0.795 0.511 0.12 0.9222 2.21 0.814 6.02 PRS_PLINK_0.00398107170553497 TRUE 512.7 Shortness of breath Both 1681 2082 9 respiratory coral4 2082, 1681 521, 396 520, 387 520, 449 521, 449 0.0562 0.0352 0.111 0.9555 1.06 0.987 1.13 -0.0393 0.0996 0.693 0.1593 0.961 0.791 1.17 0.0943 0.0991 0.341 0.4667 1.1 0.905 1.33 0.0891 0.101 0.377 0.4236 1.09 0.897 1.33 PRS_PLINK_0.00398107170553497 FALSE 512.8 Cough Both 2035 2087 9 respiratory coral4 2087, 2035 522, 471 522, 478 521, 538 522, 547 0.091 0.0332 0.00609 2.216 1.1 1.03 1.17 0.0151 0.094 0.872 0.05948 1.02 0.844 1.22 0.143 0.0939 0.128 0.8942 1.15 0.96 1.39 0.158 0.0959 0.0984 1.007 1.17 0.971 1.41 PRS_PLINK_0.00398107170553497 FALSE 512.9 Other dyspnea Both 1712 2083 9 respiratory coral4 2083, 1712 521, 382 521, 404 520, 470 521, 455 0.0866 0.0354 0.0144 1.84 1.09 1.02 1.17 0.0291 0.0998 0.771 0.1132 1.03 0.847 1.25 0.173 0.099 0.0805 1.094 1.19 0.979 1.44 0.126 0.102 0.216 0.6649 1.13 0.929 1.38 PRS_PLINK_0.00398107170553497 FALSE 513 Respiratory abnormalities Both 1995 3235 9 respiratory coral4 3235, 1995 809, 476 809, 527 808, 490 809, 501 0.0186 0.03 0.535 0.2715 1.02 0.961 1.08 0.0739 0.0834 0.375 0.4259 1.08 0.914 1.27 -0.0121 0.0854 0.887 0.05206 0.988 0.836 1.17 0.0292 0.0861 0.735 0.1338 1.03 0.87 1.22 PRS_PLINK_0.00398107170553497 FALSE 513.3 Hypoventilation Both 128 865 9 respiratory coral4 865, 128 217, 32 216, 32 216, 33 216, 31 -0.0457 0.0958 0.633 0.1983 0.955 0.792 1.15 -0.0336 0.27 0.901 0.04528 0.967 0.569 1.64 -0.0368 0.271 0.892 0.04972 0.964 0.567 1.64 -0.0505 0.277 0.856 0.06774 0.951 0.552 1.64 PRS_PLINK_0.00398107170553497 FALSE 513.31 Apnea Both 82 423 9 respiratory coral4 423, 82 106, 20 106, 16 105, 24 106, 22 0.0415 0.122 0.735 0.1338 1.04 0.82 1.32 -0.25 0.377 0.507 0.2951 0.779 0.372 1.63 0.0755 0.348 0.828 0.08177 1.08 0.545 2.13 0.034 0.362 0.925 0.03375 1.03 0.509 2.1 PRS_PLINK_0.00398107170553497 FALSE 513.32 Orthopnea Both 22 181 9 respiratory coral4 181, 22 46, 7 45, 9 45, 3 45, 3 -0.382 0.233 0.1 0.9988 0.682 0.433 1.08 0.473 0.558 0.397 0.4008 1.6 0.537 4.79 -0.994 0.722 0.169 0.7728 0.37 0.0899 1.52 -0.706 0.627 0.26 0.5852 0.493 0.144 1.69 PRS_PLINK_0.00398107170553497 TRUE 513.4 Hyperventilation Both 83 445 9 respiratory coral4 445, 83 112, 21 111, 25 111, 18 111, 19 0.015 0.119 0.9 0.0459 1.02 0.804 1.28 0.24 0.338 0.477 0.3213 1.27 0.656 2.46 -0.0935 0.358 0.794 0.1001 0.911 0.451 1.84 0.0106 0.357 0.976 0.01036 1.01 0.502 2.04 PRS_PLINK_0.00398107170553497 FALSE 513.8 Disorders of diaphragm Both 33 190 9 respiratory coral4 190, 33 48, 7 47, 6 47, 9 48, 11 0.123 0.191 0.52 0.2837 1.13 0.777 1.65 0.211 0.638 0.741 0.1303 1.23 0.354 4.31 -0.0123 0.6 0.984 0.007134 0.988 0.305 3.2 0.219 0.591 0.711 0.1481 1.25 0.391 3.97 PRS_PLINK_0.00398107170553497 TRUE 514 Abnormal findings examination of lungs Both 721 3789 9 respiratory coral4 3789, 721 948, 175 947, 199 947, 169 947, 177 -0.00816 0.0427 0.849 0.07131 0.992 0.912 1.08 0.111 0.116 0.336 0.4733 1.12 0.891 1.4 -0.0114 0.122 0.926 0.0335 0.989 0.779 1.26 -0.0452 0.122 0.712 0.1476 0.956 0.752 1.21 PRS_PLINK_0.00398107170553497 FALSE 514.1 Abnormal results of function study of pulmonary system Both 58 296 9 respiratory coral4 296, 58 74, 16 74, 16 74, 14 74, 12 -0.116 0.151 0.442 0.3542 0.89 0.662 1.2 -0.0717 0.403 0.859 0.06613 0.931 0.423 2.05 -0.141 0.41 0.731 0.1358 0.869 0.389 1.94 -0.478 0.448 0.287 0.5425 0.62 0.258 1.49 PRS_PLINK_0.00398107170553497 FALSE 514.2 Solitary pulmonary nodule Both 414 2978 9 respiratory coral4 2978, 414 745, 106 744, 112 744, 100 745, 95 -0.0317 0.0541 0.557 0.2539 0.969 0.871 1.08 0.0636 0.146 0.663 0.1785 1.07 0.8 1.42 0.0347 0.153 0.821 0.0857 1.04 0.767 1.4 -0.141 0.156 0.367 0.4354 0.869 0.64 1.18 PRS_PLINK_0.00398107170553497 FALSE 516 Abnormal sputum Both 101 761 9 respiratory coral4 761, 101 191, 35 190, 29 190, 21 190, 16 -0.245 0.115 0.0327 1.485 0.783 0.625 0.98 -0.21 0.273 0.442 0.3543 0.811 0.475 1.38 -0.558 0.299 0.0624 1.205 0.573 0.319 1.03 -0.606 0.321 0.0593 1.227 0.546 0.291 1.02 PRS_PLINK_0.00398107170553497 FALSE 516.1 Hemoptysis Both 82 631 9 respiratory coral4 631, 82 158, 27 158, 25 157, 16 158, 14 -0.186 0.124 0.133 0.8771 0.83 0.651 1.06 -0.156 0.301 0.604 0.2189 0.856 0.475 1.54 -0.55 0.337 0.102 0.9906 0.577 0.298 1.12 -0.501 0.345 0.146 0.8342 0.606 0.308 1.19 PRS_PLINK_0.00398107170553497 FALSE 519 Other diseases of respiratory system, not elsewhere classified Both 959 4138 9 respiratory coral4 4138, 959 1034, 227 1034, 264 1034, 229 1035, 239 -0.0105 0.0373 0.778 0.1089 0.99 0.92 1.06 0.133 0.102 0.193 0.7138 1.14 0.935 1.39 -0.0132 0.107 0.902 0.04472 0.987 0.8 1.22 0.0363 0.108 0.736 0.1332 1.04 0.84 1.28 PRS_PLINK_0.00398107170553497 FALSE 519.1 Tracheostomy complications Both 13 180 9 respiratory coral4 180, 13 45, 5 45, 0 45, 4 45, 4 -0.188 0.271 0.488 0.3119 0.829 0.487 1.41 -2.23 1.12 0.0472 1.326 0.108 0.012 0.972 -0.515 0.697 0.46 0.337 0.598 0.153 2.34 -0.011 0.673 0.987 0.005685 0.989 0.265 3.7 PRS_PLINK_0.00398107170553497 TRUE 519.2 Respiratory complications Both 46 351 9 respiratory coral4 351, 46 88, 19 88, 10 87, 7 88, 10 -0.325 0.166 0.0502 1.299 0.722 0.522 1 -0.553 0.419 0.186 0.7295 0.575 0.253 1.31 -1.07 0.464 0.0216 1.665 0.344 0.139 0.855 -0.748 0.439 0.0882 1.055 0.473 0.2 1.12 PRS_PLINK_0.00398107170553497 TRUE 519.8 Other diseases of respiratory system, NEC Both 258 1784 9 respiratory coral4 1784, 258 446, 57 446, 76 446, 58 446, 67 -0.000241 0.0676 0.997 0.001238 1 0.876 1.14 0.276 0.188 0.142 0.8463 1.32 0.911 1.9 0.00826 0.202 0.967 0.01443 1.01 0.679 1.5 0.17 0.199 0.394 0.4048 1.18 0.802 1.75 PRS_PLINK_0.00398107170553497 FALSE 519.9 Symptoms involving respiratory system and other chest symptoms Both 675 3623 9 respiratory coral4 3623, 675 905, 156 906, 175 905, 171 906, 173 0.00174 0.0434 0.968 0.01413 1 0.92 1.09 0.0951 0.121 0.433 0.3639 1.1 0.867 1.39 0.0738 0.124 0.551 0.2586 1.08 0.845 1.37 0.0788 0.125 0.53 0.2761 1.08 0.846 1.38 PRS_PLINK_0.00398107170553497 FALSE 520 Disorders of tooth development Both 22 325 10 digestive chartreuse4 325, 22 82, 5 81, 3 81, 10 81, 4 0.127 0.202 0.529 0.2765 1.14 0.764 1.69 -0.543 0.718 0.449 0.3473 0.581 0.142 2.37 0.666 0.52 0.2 0.6988 1.95 0.703 5.39 -0.119 0.6 0.843 0.07407 0.888 0.274 2.88 PRS_PLINK_0.00398107170553497 TRUE 520.1 Hereditary disturbances in tooth structure Both 11 167 10 digestive chartreuse4 167, 11 42, 3 42, 1 41, 5 42, 2 0.0684 0.29 0.813 0.08974 1.07 0.607 1.89 -0.685 0.862 0.427 0.3694 0.504 0.093 2.73 0.37 0.66 0.575 0.2403 1.45 0.397 5.28 -0.0879 0.831 0.916 0.03818 0.916 0.18 4.67 PRS_PLINK_0.00398107170553497 TRUE 520.2 Disturbances in tooth eruption Both 11 162 10 digestive chartreuse4 162, 11 41, 1 40, 3 40, 3 41, 4 0.224 0.277 0.419 0.378 1.25 0.727 2.15 0.798 0.958 0.405 0.3925 2.22 0.34 14.5 0.611 0.856 0.475 0.323 1.84 0.344 9.87 -0.232 0.987 0.814 0.08926 0.793 0.115 5.49 PRS_PLINK_0.00398107170553497 TRUE 521 Diseases of hard tissues of teeth Both 64 826 10 digestive chartreuse4 826, 64 207, 13 206, 17 206, 15 207, 19 -0.0206 0.138 0.882 0.05473 0.98 0.747 1.28 0.311 0.373 0.403 0.3945 1.37 0.658 2.83 0.111 0.386 0.773 0.1116 1.12 0.525 2.38 0.189 0.373 0.612 0.2129 1.21 0.582 2.51 PRS_PLINK_0.00398107170553497 FALSE 521.1 Dental caries Both 59 768 10 digestive chartreuse4 768, 59 192, 11 192, 16 192, 13 192, 19 0.0523 0.142 0.713 0.1472 1.05 0.798 1.39 0.449 0.396 0.257 0.5908 1.57 0.721 3.4 0.143 0.421 0.734 0.1344 1.15 0.506 2.63 0.358 0.389 0.357 0.4475 1.43 0.668 3.07 PRS_PLINK_0.00398107170553497 FALSE 521.2 Dental abrasion, erosion and attrition Both 6 49 10 digestive chartreuse4 49, 6 13, 2 12, 1 12, 3 12, 0 -0.754 0.677 0.265 0.576 0.471 0.125 1.77 1.21 1.69 0.474 0.3238 3.36 0.122 92.6 -0.125 1.25 0.921 0.03587 0.883 0.0756 10.3 -0.542 1.57 0.731 0.1364 0.582 0.0266 12.7 PRS_PLINK_0.00398107170553497 TRUE 522 Diseases of pulp and periapical tissues Both 50 556 10 digestive chartreuse4 556, 50 139, 12 139, 15 139, 8 139, 15 0.122 0.154 0.428 0.3683 1.13 0.835 1.53 0.111 0.401 0.782 0.1067 1.12 0.51 2.45 -0.405 0.454 0.372 0.4289 0.667 0.274 1.62 0.191 0.407 0.639 0.1945 1.21 0.545 2.69 PRS_PLINK_0.00398107170553497 TRUE 522.5 Periapical abscess Both 45 481 10 digestive chartreuse4 481, 45 121, 11 120, 12 120, 8 120, 14 0.149 0.162 0.357 0.4473 1.16 0.845 1.6 0.161 0.431 0.709 0.1495 1.17 0.504 2.74 -0.154 0.462 0.739 0.1313 0.857 0.346 2.12 0.193 0.424 0.648 0.1881 1.21 0.529 2.78 PRS_PLINK_0.00398107170553497 TRUE 523 Gingival and periodontal diseases Both 80 739 10 digestive chartreuse4 739, 80 185, 17 185, 27 184, 13 185, 23 0.178 0.126 0.158 0.8014 1.19 0.933 1.53 0.47 0.324 0.147 0.8313 1.6 0.847 3.02 -0.2 0.38 0.598 0.2232 0.819 0.389 1.72 0.389 0.354 0.271 0.5665 1.48 0.737 2.95 PRS_PLINK_0.00398107170553497 FALSE 523.1 Gingivitis Both 19 141 10 digestive chartreuse4 141, 19 36, 5 35, 5 35, 2 35, 7 0.203 0.256 0.428 0.3685 1.23 0.742 2.02 -0.29 0.679 0.67 0.1742 0.748 0.198 2.83 -2.02 1.15 0.0802 1.096 0.133 0.0138 1.27 0.0479 0.621 0.938 0.02758 1.05 0.311 3.54 PRS_PLINK_0.00398107170553497 TRUE 523.3 Periodontitis (acute or chronic) Both 32 361 10 digestive chartreuse4 361, 32 91, 5 90, 10 90, 6 90, 11 0.297 0.197 0.132 0.8797 1.35 0.914 1.98 0.371 0.555 0.504 0.2974 1.45 0.488 4.3 0.00606 0.611 0.992 0.003448 1.01 0.304 3.33 0.544 0.552 0.325 0.4879 1.72 0.583 5.08 PRS_PLINK_0.00398107170553497 TRUE 523.31 Acute periodontitis Both 27 304 10 digestive chartreuse4 304, 27 76, 3 76, 8 76, 4 76, 12 0.511 0.215 0.0177 1.752 1.67 1.09 2.54 0.572 0.674 0.396 0.4027 1.77 0.473 6.64 0.233 0.695 0.738 0.1322 1.26 0.323 4.93 1.32 0.657 0.0437 1.36 3.76 1.04 13.6 PRS_PLINK_0.00398107170553497 TRUE 523.32 Chronic periodontitis Both 9 111 10 digestive chartreuse4 111, 9 28, 2 28, 3 27, 2 28, 2 -0.0139 0.388 0.971 0.01257 0.986 0.461 2.11 0.0802 0.897 0.929 0.03209 1.08 0.187 6.28 0.000599 0.927 0.999 0.000224 1 0.163 6.15 -0.241 0.902 0.79 0.1026 0.786 0.134 4.61 PRS_PLINK_0.00398107170553497 TRUE 524 Dentofacial anomalies, including malocclusion Both 32 309 10 digestive chartreuse4 309, 32 78, 7 77, 11 77, 9 77, 5 -0.0145 0.185 0.938 0.028 0.986 0.686 1.42 0.322 0.503 0.522 0.2822 1.38 0.515 3.7 0.19 0.511 0.71 0.1488 1.21 0.444 3.29 -0.177 0.562 0.753 0.1234 0.838 0.279 2.52 PRS_PLINK_0.00398107170553497 TRUE 524.3 Anomalies of tooth position/malocclusion Both 20 165 10 digestive chartreuse4 165, 20 42, 3 41, 8 41, 6 41, 3 0.0704 0.224 0.753 0.1229 1.07 0.691 1.66 0.715 0.71 0.314 0.5028 2.04 0.508 8.22 0.426 0.686 0.535 0.2715 1.53 0.399 5.87 0.401 0.873 0.646 0.1898 1.49 0.27 8.27 PRS_PLINK_0.00398107170553497 TRUE 525 Other diseases of the teeth and supporting structures Both 121 1093 10 digestive chartreuse4 1093, 121 274, 30 273, 35 273, 27 273, 29 0.0692 0.0999 0.488 0.3115 1.07 0.881 1.3 0.197 0.262 0.453 0.3442 1.22 0.729 2.03 -0.0912 0.279 0.743 0.1287 0.913 0.529 1.58 -0.0876 0.281 0.755 0.1221 0.916 0.528 1.59 PRS_PLINK_0.00398107170553497 FALSE 525.1 Loss of teeth or edentulism Both 32 379 10 digestive chartreuse4 379, 32 95, 9 95, 12 94, 5 95, 6 0.019 0.185 0.918 0.03708 1.02 0.709 1.47 0.55 0.467 0.238 0.6232 1.73 0.695 4.33 -0.381 0.612 0.533 0.2731 0.683 0.206 2.27 -0.21 0.548 0.701 0.1542 0.81 0.277 2.37 PRS_PLINK_0.00398107170553497 TRUE 526 Diseases of the jaws Both 433 3099 10 digestive chartreuse4 3099, 433 775, 109 775, 107 774, 120 775, 97 -0.0453 0.0522 0.385 0.4146 0.956 0.863 1.06 -0.0361 0.145 0.804 0.09468 0.965 0.725 1.28 0.0276 0.145 0.849 0.07126 1.03 0.774 1.37 -0.157 0.152 0.303 0.5188 0.855 0.634 1.15 PRS_PLINK_0.00398107170553497 FALSE 526.1 Cysts of the jaws Both 12 180 10 digestive chartreuse4 180, 12 45, 5 45, 2 45, 3 45, 2 -0.604 0.321 0.0593 1.227 0.546 0.292 1.02 -0.722 0.708 0.307 0.5123 0.486 0.121 1.94 -0.658 0.752 0.381 0.4191 0.518 0.119 2.26 -2.83 1.39 0.0421 1.376 0.0593 0.00389 0.904 PRS_PLINK_0.00398107170553497 TRUE 526.3 Anomalies of jaw size/symmetry Both 25 182 10 digestive chartreuse4 182, 25 46, 2 45, 3 45, 11 46, 9 0.343 0.228 0.133 0.8762 1.41 0.901 2.2 0.231 0.789 0.77 0.1137 1.26 0.269 5.91 1.17 0.725 0.108 0.9686 3.21 0.776 13.3 1.37 0.787 0.0825 1.083 3.92 0.839 18.3 PRS_PLINK_0.00398107170553497 TRUE 526.4 Temporomandibular joint disorders Both 298 1947 10 digestive chartreuse4 1947, 298 487, 75 487, 77 486, 83 487, 63 -0.0539 0.0629 0.392 0.4072 0.948 0.838 1.07 -0.00149 0.175 0.993 0.002969 0.999 0.709 1.41 0.0418 0.175 0.811 0.09074 1.04 0.74 1.47 -0.193 0.187 0.301 0.5209 0.824 0.571 1.19 PRS_PLINK_0.00398107170553497 FALSE 526.41 Temporomandibular joint disorder, unspecified Both 226 1567 10 digestive chartreuse4 1567, 226 392, 61 392, 58 391, 63 392, 44 -0.116 0.0739 0.117 0.9318 0.891 0.77 1.03 -0.104 0.197 0.596 0.2249 0.901 0.612 1.32 -0.013 0.195 0.947 0.02366 0.987 0.673 1.45 -0.297 0.214 0.164 0.7858 0.743 0.489 1.13 PRS_PLINK_0.00398107170553497 FALSE 526.42 Arthralgia/ankylosis of temporomandibular joint Both 136 934 10 digestive chartreuse4 934, 136 234, 28 233, 34 233, 39 234, 35 0.113 0.0913 0.217 0.6629 1.12 0.936 1.34 0.185 0.268 0.49 0.3094 1.2 0.711 2.03 0.235 0.265 0.375 0.4258 1.27 0.752 2.13 0.176 0.272 0.518 0.2857 1.19 0.7 2.03 PRS_PLINK_0.00398107170553497 FALSE 526.5 Inflammatory conditions of jaw Both 23 298 10 digestive chartreuse4 298, 23 75, 1 74, 10 74, 8 75, 4 0.0693 0.239 0.772 0.1125 1.07 0.671 1.71 1.74 0.787 0.0273 1.564 5.68 1.21 26.5 1.58 0.831 0.0566 1.247 4.87 0.956 24.8 1.43 0.926 0.123 0.9103 4.17 0.679 25.6 PRS_PLINK_0.00398107170553497 TRUE 526.8 Exostosis of jaw Both 9 60 10 digestive chartreuse4 60, 9 15, 4 15, 2 15, 1 15, 2 -0.0214 0.441 0.961 0.01717 0.979 0.413 2.32 -0.308 1.03 0.764 0.1167 0.735 0.0978 5.52 -1.06 1.28 0.411 0.3861 0.348 0.028 4.32 0.619 1.4 0.659 0.1808 1.86 0.118 29.1 PRS_PLINK_0.00398107170553497 TRUE 526.9 Jaw disease NOS Both 64 528 10 digestive chartreuse4 528, 64 132, 11 132, 21 132, 13 132, 19 0.0278 0.135 0.837 0.07711 1.03 0.789 1.34 0.58 0.387 0.133 0.8749 1.79 0.837 3.81 0.068 0.426 0.873 0.05891 1.07 0.465 2.47 0.539 0.415 0.194 0.7132 1.71 0.761 3.87 PRS_PLINK_0.00398107170553497 FALSE 527 Diseases of the salivary glands Both 239 1840 10 digestive chartreuse4 1840, 239 460, 52 460, 74 460, 52 460, 61 0.0938 0.0701 0.181 0.7435 1.1 0.957 1.26 0.366 0.195 0.0601 1.221 1.44 0.985 2.11 0.0106 0.21 0.96 0.01789 1.01 0.67 1.53 0.217 0.207 0.294 0.5312 1.24 0.828 1.86 PRS_PLINK_0.00398107170553497 FALSE 527.1 Hypertrophy of salivary gland Both 5 71 10 digestive chartreuse4 71, 5 18, 3 18, 0 17, 1 18, 1 -0.646 0.432 0.135 0.8712 0.524 0.225 1.22 -1.5 1.37 0.272 0.5658 0.222 0.0152 3.25 -1.07 1.07 0.317 0.4994 0.342 0.0419 2.79 -1.18 1.09 0.278 0.5558 0.308 0.0366 2.59 PRS_PLINK_0.00398107170553497 TRUE 527.2 Sialoadenitis Both 61 453 10 digestive chartreuse4 453, 61 114, 17 113, 12 113, 12 113, 20 0.0828 0.14 0.553 0.2572 1.09 0.826 1.43 -0.208 0.39 0.595 0.2257 0.813 0.378 1.75 -0.234 0.402 0.561 0.251 0.792 0.36 1.74 0.243 0.371 0.512 0.2911 1.28 0.617 2.64 PRS_PLINK_0.00398107170553497 FALSE 527.7 Disturbance of salivary secretion Both 131 1000 10 digestive chartreuse4 1000, 131 250, 29 250, 41 250, 27 250, 34 0.11 0.0946 0.243 0.6138 1.12 0.928 1.34 0.347 0.26 0.181 0.7424 1.42 0.851 2.35 -0.0973 0.282 0.73 0.1367 0.907 0.522 1.58 0.159 0.271 0.556 0.2546 1.17 0.69 1.99 PRS_PLINK_0.00398107170553497 FALSE 527.8 Other specified diseases of the salivary glands Both 29 256 10 digestive chartreuse4 256, 29 64, 2 64, 11 64, 8 64, 8 0.17 0.193 0.378 0.4221 1.19 0.812 1.73 1.29 0.694 0.0633 1.199 3.63 0.931 14.2 1.51 0.723 0.0366 1.437 4.53 1.1 18.7 1.27 0.737 0.0836 1.078 3.58 0.844 15.2 PRS_PLINK_0.00398107170553497 TRUE 528 Diseases of the oral soft tissues, excluding lesions specific for gingiva and tongue Both 425 2966 10 digestive chartreuse4 2966, 425 741, 110 741, 100 741, 109 742, 106 0.0223 0.0534 0.676 0.17 1.02 0.921 1.14 -0.0536 0.148 0.718 0.144 0.948 0.709 1.27 0.0124 0.148 0.933 0.0301 1.01 0.758 1.35 -0.0284 0.15 0.85 0.07058 0.972 0.724 1.3 PRS_PLINK_0.00398107170553497 FALSE 528.1 Stomatitis and mucositis Both 126 804 10 digestive chartreuse4 804, 126 201, 39 201, 26 201, 31 201, 30 -0.062 0.101 0.54 0.2679 0.94 0.771 1.15 -0.329 0.271 0.225 0.6483 0.72 0.423 1.22 -0.259 0.263 0.323 0.4908 0.771 0.461 1.29 -0.259 0.269 0.337 0.4728 0.772 0.455 1.31 PRS_PLINK_0.00398107170553497 FALSE 528.11 Stomatitis and mucositis (ulcerative) Both 37 246 10 digestive chartreuse4 246, 37 62, 11 61, 6 61, 11 62, 9 -0.00463 0.192 0.981 0.00844 0.995 0.683 1.45 -0.342 0.518 0.509 0.2929 0.71 0.257 1.96 0.0693 0.474 0.884 0.05359 1.07 0.423 2.72 -0.37 0.524 0.48 0.3183 0.691 0.247 1.93 PRS_PLINK_0.00398107170553497 TRUE 528.12 Oral aphthae Both 56 307 10 digestive chartreuse4 307, 56 77, 16 77, 12 76, 17 77, 11 -0.0484 0.149 0.746 0.1273 0.953 0.711 1.28 -0.176 0.413 0.67 0.1741 0.839 0.373 1.88 0.0234 0.393 0.952 0.02118 1.02 0.474 2.21 -0.437 0.434 0.313 0.5043 0.646 0.276 1.51 PRS_PLINK_0.00398107170553497 FALSE 528.3 Cellulitis and abscess of oral soft tissues Both 25 211 10 digestive chartreuse4 211, 25 53, 4 53, 9 52, 6 53, 6 0.205 0.229 0.37 0.4315 1.23 0.784 1.92 1.21 0.682 0.0765 1.117 3.35 0.879 12.8 0.176 0.676 0.795 0.09964 1.19 0.317 4.48 0.493 0.678 0.467 0.3304 1.64 0.433 6.19 PRS_PLINK_0.00398107170553497 TRUE 528.4 Cysts of oral soft tissues Both 17 134 10 digestive chartreuse4 134, 17 34, 2 33, 6 33, 4 34, 5 0.352 0.25 0.159 0.7987 1.42 0.871 2.32 0.943 0.726 0.194 0.7125 2.57 0.619 10.7 0.444 0.765 0.562 0.2504 1.56 0.348 6.98 0.658 0.794 0.407 0.3903 1.93 0.407 9.16 PRS_PLINK_0.00398107170553497 TRUE 528.41 Cyst of the salivary gland Both 11 73 10 digestive chartreuse4 73, 11 19, 1 18, 2 18, 4 18, 4 0.554 0.344 0.107 0.9703 1.74 0.887 3.41 1.04 1.1 0.341 0.4672 2.84 0.331 24.4 0.83 1.04 0.427 0.3696 2.29 0.296 17.8 1.2 1.04 0.251 0.5997 3.31 0.428 25.6 PRS_PLINK_0.00398107170553497 TRUE 528.5 Diseases of lips Both 109 590 10 digestive chartreuse4 590, 109 148, 28 147, 22 147, 27 148, 32 0.0881 0.109 0.417 0.3797 1.09 0.883 1.35 -0.0875 0.308 0.776 0.1101 0.916 0.501 1.67 -0.0441 0.297 0.882 0.05464 0.957 0.535 1.71 0.0669 0.296 0.821 0.08556 1.07 0.599 1.91 PRS_PLINK_0.00398107170553497 FALSE 528.6 Leukoplakia of oral mucosa Both 12 139 10 digestive chartreuse4 139, 12 35, 4 35, 3 34, 3 35, 2 -0.454 0.353 0.198 0.7033 0.635 0.318 1.27 -0.251 0.812 0.757 0.1207 0.778 0.159 3.82 -0.0924 0.855 0.914 0.03906 0.912 0.17 4.88 -1.21 0.98 0.218 0.661 0.299 0.0439 2.04 PRS_PLINK_0.00398107170553497 TRUE 528.7 Sialolithiasis Both 22 177 10 digestive chartreuse4 177, 22 45, 4 44, 7 44, 8 44, 3 0.0462 0.219 0.833 0.07943 1.05 0.682 1.61 0.4 0.646 0.535 0.2713 1.49 0.421 5.29 0.765 0.667 0.251 0.5997 2.15 0.582 7.93 -0.602 0.887 0.498 0.303 0.548 0.0963 3.12 PRS_PLINK_0.00398107170553497 TRUE 529 Diseases and other conditions of the tongue Both 107 741 10 digestive chartreuse4 741, 107 185, 30 185, 30 185, 21 185, 26 -0.0969 0.107 0.363 0.4403 0.908 0.737 1.12 0.0286 0.277 0.918 0.03724 1.03 0.597 1.77 -0.516 0.308 0.0942 1.026 0.597 0.326 1.09 -0.134 0.294 0.647 0.1891 0.874 0.492 1.55 PRS_PLINK_0.00398107170553497 FALSE 529.1 Glossitis Both 25 155 10 digestive chartreuse4 155, 25 38, 7 39, 6 38, 8 39, 4 -0.0512 0.207 0.805 0.09435 0.95 0.633 1.43 -0.309 0.637 0.628 0.2023 0.734 0.211 2.56 0.224 0.549 0.683 0.1658 1.25 0.427 3.67 -0.513 0.661 0.437 0.3593 0.598 0.164 2.19 PRS_PLINK_0.00398107170553497 TRUE 529.6 Glossodynia Both 28 186 10 digestive chartreuse4 186, 28 47, 9 46, 7 46, 3 47, 9 0.0141 0.186 0.94 0.02693 1.01 0.704 1.46 0.0784 0.543 0.885 0.05292 1.08 0.373 3.14 -0.88 0.645 0.173 0.7631 0.415 0.117 1.47 0.0597 0.532 0.911 0.04062 1.06 0.374 3.01 PRS_PLINK_0.00398107170553497 TRUE 530 Diseases of esophagus Both 2358 2700 10 digestive chartreuse4 2700, 2358 674, 567 675, 571 675, 622 675, 598 0.0566 0.0298 0.0572 1.242 1.06 0.998 1.12 -0.00479 0.0838 0.954 0.02029 0.995 0.845 1.17 0.0934 0.0839 0.265 0.5764 1.1 0.932 1.29 0.0579 0.0853 0.497 0.3032 1.06 0.896 1.25 PRS_PLINK_0.00398107170553497 FALSE 530.1 Esophagitis, GERD and related diseases Both 2311 2700 10 digestive chartreuse4 2700, 2311 674, 554 675, 559 675, 610 675, 588 0.0595 0.0299 0.0469 1.329 1.06 1 1.13 -0.00354 0.0843 0.966 0.01481 0.996 0.845 1.18 0.0958 0.0843 0.256 0.592 1.1 0.933 1.3 0.0639 0.0857 0.456 0.3409 1.07 0.901 1.26 PRS_PLINK_0.00398107170553497 FALSE 530.11 GERD Both 2249 2699 10 digestive chartreuse4 2699, 2249 674, 542 675, 547 674, 595 675, 565 0.0521 0.0301 0.0837 1.077 1.05 0.993 1.12 -0.00166 0.0847 0.984 0.006852 0.998 0.846 1.18 0.0964 0.0848 0.256 0.5918 1.1 0.932 1.3 0.0487 0.0865 0.573 0.2415 1.05 0.886 1.24 PRS_PLINK_0.00398107170553497 FALSE 530.12 Ulcer of esophagus Both 66 352 10 digestive chartreuse4 352, 66 88, 10 88, 17 88, 17 88, 22 0.28 0.133 0.0346 1.461 1.32 1.02 1.72 0.393 0.425 0.355 0.4499 1.48 0.644 3.41 0.618 0.425 0.146 0.8349 1.85 0.806 4.27 0.756 0.419 0.0716 1.145 2.13 0.936 4.84 PRS_PLINK_0.00398107170553497 FALSE 530.13 Barrett's esophagus Both 73 642 10 digestive chartreuse4 642, 73 161, 21 160, 19 160, 16 161, 17 -0.0451 0.127 0.723 0.1408 0.956 0.745 1.23 -0.0503 0.334 0.88 0.05533 0.951 0.494 1.83 -0.3 0.353 0.395 0.4032 0.741 0.37 1.48 0.0386 0.352 0.913 0.03961 1.04 0.521 2.07 PRS_PLINK_0.00398107170553497 FALSE 530.14 Reflux esophagitis Both 381 1956 10 digestive chartreuse4 1956, 381 488, 76 489, 95 489, 113 489, 97 0.105 0.0579 0.0713 1.147 1.11 0.991 1.24 0.222 0.17 0.191 0.7187 1.25 0.895 1.74 0.383 0.167 0.0215 1.667 1.47 1.06 2.03 0.158 0.175 0.367 0.4353 1.17 0.831 1.65 PRS_PLINK_0.00398107170553497 FALSE 530.15 Eosinophilic esophagitis Both 55 234 10 digestive chartreuse4 234, 55 59, 17 58, 15 58, 8 59, 15 -0.0371 0.165 0.822 0.08505 0.964 0.698 1.33 -0.18 0.421 0.669 0.1746 0.835 0.366 1.91 -0.751 0.482 0.119 0.9243 0.472 0.183 1.21 -0.197 0.46 0.668 0.175 0.821 0.333 2.02 PRS_PLINK_0.00398107170553497 FALSE 530.2 Esophageal bleeding (varices/hemorrhage) Both 65 571 10 digestive chartreuse4 571, 65 143, 16 143, 18 142, 15 143, 16 -0.138 0.133 0.297 0.5271 0.871 0.672 1.13 0.105 0.367 0.774 0.1113 1.11 0.541 2.28 -0.248 0.378 0.511 0.2915 0.78 0.372 1.64 -0.181 0.388 0.641 0.1932 0.834 0.39 1.79 PRS_PLINK_0.00398107170553497 FALSE 530.3 Stricture and stenosis of esophagus Both 133 888 10 digestive chartreuse4 888, 133 222, 30 222, 36 222, 25 222, 42 0.139 0.0903 0.123 0.91 1.15 0.963 1.37 0.152 0.262 0.561 0.2507 1.16 0.696 1.95 -0.135 0.29 0.642 0.1921 0.874 0.495 1.54 0.329 0.263 0.211 0.6759 1.39 0.83 2.33 PRS_PLINK_0.00398107170553497 FALSE 530.5 Disorders of esophageal motility Both 88 606 10 digestive chartreuse4 606, 88 152, 21 151, 18 151, 23 152, 26 0.0595 0.117 0.611 0.2142 1.06 0.844 1.33 -0.0627 0.344 0.855 0.0678 0.939 0.479 1.84 0.15 0.332 0.652 0.1861 1.16 0.606 2.23 0.14 0.332 0.673 0.1717 1.15 0.6 2.2 PRS_PLINK_0.00398107170553497 FALSE 530.6 Diverticulum of esophagus, acquired Both 8 95 10 digestive chartreuse4 95, 8 24, 1 24, 3 23, 1 24, 3 0.183 0.395 0.644 0.1914 1.2 0.553 2.61 1.34 1.13 0.238 0.6235 3.8 0.414 35 0.306 1.34 0.819 0.08691 1.36 0.0992 18.6 0.915 1.14 0.423 0.374 2.5 0.267 23.4 PRS_PLINK_0.00398107170553497 TRUE 530.7 Gastroesophageal laceration-hemorrhage syndrome Both 16 95 10 digestive chartreuse4 95, 16 24, 2 24, 2 23, 4 24, 8 0.573 0.327 0.0796 1.099 1.77 0.935 3.36 0.369 0.958 0.7 0.1547 1.45 0.221 9.46 1.96 1.85 0.29 0.5381 7.13 0.188 270 1.53 0.969 0.115 0.9376 4.6 0.688 30.8 PRS_PLINK_0.00398107170553497 TRUE 530.9 Heartburn Both 291 1747 10 digestive chartreuse4 1747, 291 437, 68 437, 78 436, 78 437, 67 0.0133 0.0651 0.838 0.07677 1.01 0.892 1.15 0.134 0.181 0.461 0.3367 1.14 0.801 1.63 0.0928 0.184 0.614 0.2121 1.1 0.765 1.57 -0.0254 0.192 0.895 0.04832 0.975 0.67 1.42 PRS_PLINK_0.00398107170553497 FALSE 531 Peptic ulcer (excl. esophageal) Both 314 2365 10 digestive chartreuse4 2365, 314 592, 73 591, 81 591, 76 591, 83 0.0108 0.0599 0.857 0.06703 1.01 0.899 1.14 0.0979 0.172 0.57 0.2443 1.1 0.787 1.55 0.0788 0.176 0.654 0.1847 1.08 0.767 1.53 0.107 0.174 0.539 0.2687 1.11 0.792 1.56 PRS_PLINK_0.00398107170553497 FALSE 531.1 Hemorrhage from gastrointestinal ulcer Both 54 369 10 digestive chartreuse4 369, 54 93, 11 92, 17 92, 12 92, 14 0.00822 0.142 0.954 0.0205 1.01 0.763 1.33 0.336 0.416 0.419 0.3777 1.4 0.619 3.16 0.0846 0.447 0.85 0.07071 1.09 0.453 2.61 0.246 0.426 0.563 0.2493 1.28 0.555 2.95 PRS_PLINK_0.00398107170553497 FALSE 531.2 Gastric ulcer Both 188 1392 10 digestive chartreuse4 1392, 188 348, 36 348, 53 348, 46 348, 52 0.0444 0.0778 0.568 0.2456 1.05 0.898 1.22 0.365 0.229 0.11 0.9586 1.44 0.921 2.26 0.267 0.236 0.258 0.5879 1.31 0.822 2.07 0.312 0.233 0.18 0.7436 1.37 0.865 2.16 PRS_PLINK_0.00398107170553497 FALSE 531.3 Duodenal ulcer Both 63 422 10 digestive chartreuse4 422, 63 106, 14 105, 20 105, 14 106, 15 0.0732 0.135 0.588 0.2305 1.08 0.826 1.4 0.253 0.368 0.492 0.3083 1.29 0.626 2.65 0.075 0.399 0.851 0.07016 1.08 0.494 2.35 0.14 0.407 0.731 0.1359 1.15 0.518 2.56 PRS_PLINK_0.00398107170553497 FALSE 531.4 Peptic ulcer, site unspecified Both 156 999 10 digestive chartreuse4 999, 156 250, 31 250, 47 249, 44 250, 34 -0.00634 0.0868 0.942 0.02607 0.994 0.838 1.18 0.357 0.247 0.149 0.8259 1.43 0.88 2.32 0.356 0.249 0.154 0.8137 1.43 0.875 2.33 0.0943 0.265 0.722 0.1416 1.1 0.654 1.85 PRS_PLINK_0.00398107170553497 FALSE 531.5 Gastrojejunal ulcer Both 23 180 10 digestive chartreuse4 180, 23 45, 8 45, 4 45, 4 45, 7 -0.123 0.225 0.583 0.2344 0.884 0.569 1.37 -0.55 0.607 0.365 0.4377 0.577 0.176 1.9 -0.587 0.627 0.349 0.4572 0.556 0.163 1.9 -0.129 0.542 0.812 0.09052 0.879 0.304 2.54 PRS_PLINK_0.00398107170553497 TRUE 532 Dysphagia Both 807 2574 10 digestive chartreuse4 2574, 807 643, 178 643, 211 643, 226 644, 192 0.069 0.0426 0.105 0.9772 1.07 0.986 1.16 0.163 0.121 0.177 0.7528 1.18 0.929 1.49 0.241 0.121 0.0453 1.344 1.27 1.01 1.61 0.04 0.127 0.752 0.1237 1.04 0.812 1.33 PRS_PLINK_0.00398107170553497 FALSE 535 Gastritis and duodenitis Both 490 3089 10 digestive chartreuse4 3089, 490 773, 115 772, 126 772, 131 772, 117 0.0355 0.0498 0.476 0.3223 1.04 0.94 1.14 0.0913 0.14 0.513 0.29 1.1 0.833 1.44 0.132 0.14 0.348 0.4588 1.14 0.867 1.5 0.0141 0.145 0.923 0.03498 1.01 0.763 1.35 PRS_PLINK_0.00398107170553497 FALSE 535.1 Acute gastritis Both 187 1353 10 digestive chartreuse4 1353, 187 339, 46 338, 48 338, 50 338, 42 -0.0531 0.0789 0.501 0.3004 0.948 0.812 1.11 0.063 0.222 0.777 0.1098 1.06 0.689 1.65 0.15 0.221 0.497 0.3039 1.16 0.754 1.79 -0.0491 0.232 0.832 0.0798 0.952 0.604 1.5 PRS_PLINK_0.00398107170553497 FALSE 535.2 Atrophic gastritis Both 66 381 10 digestive chartreuse4 381, 66 96, 17 95, 17 95, 21 95, 11 -0.123 0.143 0.392 0.4069 0.885 0.668 1.17 -0.0661 0.375 0.86 0.06551 0.936 0.449 1.95 0.122 0.362 0.736 0.1329 1.13 0.556 2.3 -0.492 0.413 0.234 0.6315 0.611 0.272 1.37 PRS_PLINK_0.00398107170553497 FALSE 535.6 Duodenitis Both 47 297 10 digestive chartreuse4 297, 47 75, 11 74, 6 74, 21 74, 9 -0.0472 0.156 0.762 0.1182 0.954 0.703 1.29 -0.498 0.521 0.34 0.4691 0.608 0.219 1.69 0.573 0.419 0.172 0.7651 1.77 0.78 4.04 -0.269 0.491 0.583 0.2342 0.764 0.292 2 PRS_PLINK_0.00398107170553497 TRUE 535.8 Other specified gastritis Both 130 723 10 digestive chartreuse4 723, 130 181, 22 181, 41 180, 35 181, 32 0.112 0.102 0.273 0.5632 1.12 0.915 1.37 0.507 0.29 0.0801 1.097 1.66 0.941 2.93 0.437 0.303 0.149 0.8269 1.55 0.855 2.8 0.445 0.307 0.147 0.8319 1.56 0.855 2.85 PRS_PLINK_0.00398107170553497 FALSE 535.9 Gastritis and duodenitis, NOS Both 238 1458 10 digestive chartreuse4 1458, 238 365, 63 364, 61 364, 62 365, 52 0.00657 0.0719 0.927 0.0328 1.01 0.874 1.16 -0.0149 0.194 0.939 0.02745 0.985 0.673 1.44 -0.0377 0.197 0.849 0.0712 0.963 0.654 1.42 -0.216 0.205 0.292 0.534 0.806 0.539 1.2 PRS_PLINK_0.00398107170553497 FALSE 536 Disorders of function of stomach Both 598 3192 10 digestive chartreuse4 3192, 598 798, 151 798, 146 798, 143 798, 158 0.0245 0.046 0.595 0.2253 1.02 0.936 1.12 -0.0653 0.127 0.609 0.2157 0.937 0.73 1.2 -0.0844 0.129 0.513 0.2898 0.919 0.714 1.18 0.00297 0.129 0.982 0.008066 1 0.78 1.29 PRS_PLINK_0.00398107170553497 FALSE 536.3 Gastroparesis Both 121 904 10 digestive chartreuse4 904, 121 226, 27 226, 28 226, 31 226, 35 0.102 0.0999 0.309 0.5096 1.11 0.91 1.35 0.104 0.285 0.715 0.1455 1.11 0.635 1.94 0.166 0.284 0.56 0.252 1.18 0.676 2.06 0.333 0.283 0.24 0.6207 1.4 0.801 2.43 PRS_PLINK_0.00398107170553497 FALSE 536.7 Complications of gastrostomy, colostomy and enterostomy Both 38 374 10 digestive chartreuse4 374, 38 94, 8 93, 11 93, 7 94, 12 0.0693 0.175 0.692 0.1598 1.07 0.761 1.51 0.251 0.469 0.592 0.2273 1.29 0.512 3.23 -0.135 0.532 0.799 0.09734 0.873 0.308 2.48 0.463 0.473 0.327 0.4848 1.59 0.629 4.02 PRS_PLINK_0.00398107170553497 TRUE 536.8 Dyspepsia and other specified disorders of function of stomach Both 497 2558 10 digestive chartreuse4 2558, 497 640, 131 639, 124 639, 119 640, 123 -0.0158 0.0511 0.758 0.1206 0.984 0.891 1.09 -0.0977 0.139 0.481 0.3176 0.907 0.691 1.19 -0.135 0.141 0.338 0.4713 0.874 0.663 1.15 -0.0876 0.143 0.539 0.2684 0.916 0.693 1.21 PRS_PLINK_0.00398107170553497 FALSE 537 Other disorders of stomach and duodenum Both 523 3323 10 digestive chartreuse4 3323, 523 831, 122 831, 137 830, 135 831, 129 0.0348 0.0483 0.471 0.3272 1.04 0.942 1.14 0.114 0.135 0.398 0.4006 1.12 0.861 1.46 0.0986 0.137 0.471 0.3271 1.1 0.844 1.44 0.0838 0.14 0.551 0.2591 1.09 0.826 1.43 PRS_PLINK_0.00398107170553497 FALSE 537.1 Lesions of stomach and duodenum Both 19 188 10 digestive chartreuse4 188, 19 47, 5 47, 7 47, 5 47, 2 -0.458 0.273 0.0925 1.034 0.632 0.371 1.08 -0.17 0.633 0.788 0.1033 0.844 0.244 2.92 -0.72 0.856 0.4 0.3976 0.487 0.091 2.6 -1.73 1.01 0.0877 1.057 0.177 0.0243 1.29 PRS_PLINK_0.00398107170553497 TRUE 539 Bariatric surgery Both 240 2002 10 digestive chartreuse4 2002, 240 500, 63 500, 55 500, 63 501, 59 0.0249 0.0686 0.716 0.1449 1.03 0.896 1.17 -0.115 0.194 0.554 0.2565 0.891 0.609 1.3 0.00473 0.191 0.98 0.008645 1 0.69 1.46 0.0138 0.195 0.944 0.02517 1.01 0.692 1.49 PRS_PLINK_0.00398107170553497 FALSE 540 Appendiceal conditions Both 99 554 10 digestive chartreuse4 554, 99 139, 20 138, 19 138, 27 139, 33 0.182 0.113 0.109 0.9633 1.2 0.96 1.5 -0.0511 0.342 0.881 0.05488 0.95 0.486 1.86 0.143 0.326 0.661 0.1797 1.15 0.609 2.19 0.46 0.318 0.148 0.8299 1.58 0.849 2.95 PRS_PLINK_0.00398107170553497 FALSE 540.1 Appendicitis Both 81 448 10 digestive chartreuse4 448, 81 112, 15 112, 16 112, 20 112, 30 0.25 0.123 0.0424 1.372 1.28 1.01 1.63 0.0608 0.377 0.872 0.05952 1.06 0.507 2.23 0.214 0.368 0.561 0.2507 1.24 0.602 2.55 0.603 0.348 0.083 1.081 1.83 0.924 3.62 PRS_PLINK_0.00398107170553497 FALSE 540.11 Acute appendicitis Both 76 398 10 digestive chartreuse4 398, 76 100, 14 99, 14 99, 21 100, 27 0.26 0.13 0.0454 1.343 1.3 1.01 1.67 -0.0822 0.401 0.838 0.07691 0.921 0.42 2.02 0.324 0.373 0.384 0.4158 1.38 0.667 2.87 0.616 0.364 0.0909 1.042 1.85 0.907 3.78 PRS_PLINK_0.00398107170553497 FALSE 550 Abdominal hernia Both 974 3990 10 digestive chartreuse4 3990, 974 997, 206 997, 221 997, 266 998, 281 0.105 0.0377 0.00556 2.255 1.11 1.03 1.2 0.0144 0.109 0.895 0.04802 1.01 0.819 1.26 0.188 0.108 0.0806 1.094 1.21 0.977 1.49 0.222 0.108 0.0398 1.4 1.25 1.01 1.54 PRS_PLINK_0.00398107170553497 FALSE 550.1 Inguinal hernia Both 267 993 10 digestive chartreuse4 993, 267 249, 50 248, 66 248, 68 248, 83 0.185 0.0729 0.011 1.958 1.2 1.04 1.39 0.248 0.213 0.244 0.6122 1.28 0.844 1.95 0.343 0.215 0.11 0.9596 1.41 0.925 2.15 0.543 0.213 0.0107 1.971 1.72 1.13 2.61 PRS_PLINK_0.00398107170553497 FALSE 550.2 Diaphragmatic hernia Both 462 3030 10 digestive chartreuse4 3030, 462 757, 100 757, 112 757, 131 758, 119 0.0879 0.0513 0.0862 1.065 1.09 0.988 1.21 0.111 0.147 0.45 0.3471 1.12 0.838 1.49 0.216 0.144 0.134 0.8736 1.24 0.936 1.65 0.143 0.149 0.337 0.472 1.15 0.861 1.55 PRS_PLINK_0.00398107170553497 FALSE 550.3 Femoral hernia Both 37 150 10 digestive chartreuse4 150, 37 38, 13 37, 8 37, 10 38, 6 -0.0469 0.204 0.818 0.08724 0.954 0.64 1.42 -0.301 0.507 0.553 0.257 0.74 0.274 2 -0.185 0.485 0.703 0.153 0.831 0.321 2.15 -0.429 0.581 0.461 0.3365 0.651 0.209 2.03 PRS_PLINK_0.00398107170553497 TRUE 550.4 Umbilical hernia Both 150 1121 10 digestive chartreuse4 1121, 150 281, 43 280, 26 280, 34 280, 47 0.0604 0.0888 0.497 0.3039 1.06 0.892 1.26 -0.531 0.26 0.041 1.387 0.588 0.354 0.979 -0.209 0.248 0.398 0.3999 0.811 0.499 1.32 0.0873 0.234 0.709 0.1493 1.09 0.69 1.73 PRS_PLINK_0.00398107170553497 FALSE 550.5 Ventral hernia Both 270 2271 10 digestive chartreuse4 2271, 270 568, 60 568, 61 567, 71 568, 78 0.0794 0.0661 0.229 0.6394 1.08 0.951 1.23 -0.0021 0.191 0.991 0.003819 0.998 0.686 1.45 0.201 0.189 0.289 0.5388 1.22 0.843 1.77 0.337 0.191 0.0782 1.107 1.4 0.963 2.04 PRS_PLINK_0.00398107170553497 FALSE 550.6 Incisional hernia Both 151 1361 10 digestive chartreuse4 1361, 151 341, 41 340, 29 340, 42 340, 39 0.0264 0.0886 0.766 0.116 1.03 0.863 1.22 -0.35 0.251 0.163 0.7869 0.705 0.431 1.15 0.032 0.235 0.892 0.04969 1.03 0.651 1.64 -0.00692 0.246 0.978 0.009873 0.993 0.614 1.61 PRS_PLINK_0.00398107170553497 FALSE 555 Inflammatory bowel disease and other gastroenteritis and colitis Both 202 1234 10 digestive chartreuse4 1234, 202 309, 44 308, 47 308, 51 309, 60 0.0805 0.0778 0.301 0.522 1.08 0.931 1.26 0.0747 0.227 0.742 0.1295 1.08 0.69 1.68 0.273 0.227 0.229 0.6407 1.31 0.843 2.05 0.331 0.222 0.136 0.8664 1.39 0.901 2.15 PRS_PLINK_0.00398107170553497 FALSE 555.1 Regional enteritis Both 112 696 10 digestive chartreuse4 696, 112 174, 28 174, 26 174, 24 174, 34 0.0252 0.103 0.807 0.09298 1.03 0.837 1.26 -0.0999 0.298 0.737 0.1323 0.905 0.505 1.62 -0.0369 0.299 0.902 0.0449 0.964 0.536 1.73 0.199 0.288 0.489 0.3104 1.22 0.694 2.15 PRS_PLINK_0.00398107170553497 FALSE 555.2 Ulcerative colitis Both 129 751 10 digestive chartreuse4 751, 129 188, 26 188, 30 187, 35 188, 38 0.0884 0.0996 0.375 0.4262 1.09 0.899 1.33 0.0636 0.285 0.823 0.08444 1.07 0.61 1.86 0.354 0.282 0.21 0.6787 1.42 0.82 2.48 0.386 0.283 0.173 0.7609 1.47 0.844 2.56 PRS_PLINK_0.00398107170553497 FALSE 555.21 Ulcerative colitis (chronic) Both 79 413 10 digestive chartreuse4 413, 79 104, 16 103, 19 103, 14 103, 30 0.163 0.129 0.207 0.6848 1.18 0.914 1.52 0.102 0.361 0.778 0.1092 1.11 0.546 2.25 -0.0682 0.391 0.862 0.06467 0.934 0.434 2.01 0.643 0.345 0.0628 1.202 1.9 0.966 3.74 PRS_PLINK_0.00398107170553497 FALSE 556 Ulceration of the lower GI tract Both 112 528 10 digestive chartreuse4 528, 112 132, 26 132, 28 132, 25 132, 33 0.0865 0.106 0.414 0.3831 1.09 0.886 1.34 0.0326 0.311 0.917 0.03779 1.03 0.561 1.9 -0.129 0.312 0.679 0.1684 0.879 0.477 1.62 0.121 0.3 0.687 0.1631 1.13 0.627 2.03 PRS_PLINK_0.00398107170553497 FALSE 556.1 Ulceration of intestine Both 100 476 10 digestive chartreuse4 476, 100 119, 23 119, 24 119, 25 119, 28 0.0963 0.113 0.396 0.4028 1.1 0.882 1.38 -0.0395 0.335 0.906 0.04285 0.961 0.499 1.85 -0.057 0.325 0.861 0.06511 0.945 0.499 1.79 0.161 0.322 0.617 0.2095 1.17 0.625 2.21 PRS_PLINK_0.00398107170553497 FALSE 556.11 Angiodysplasia of intestine (without mention of hemorrhage) Both 36 161 10 digestive chartreuse4 161, 36 41, 13 40, 7 40, 7 40, 9 0.0288 0.194 0.882 0.05454 1.03 0.704 1.5 -0.518 0.573 0.366 0.4367 0.596 0.194 1.83 -0.711 0.555 0.2 0.6995 0.491 0.166 1.46 -0.149 0.508 0.77 0.1137 0.862 0.318 2.33 PRS_PLINK_0.00398107170553497 TRUE 557 Intestinal malabsorption (non-celiac) Both 353 1640 10 digestive chartreuse4 1640, 353 410, 95 410, 87 410, 80 410, 91 0.0304 0.0603 0.614 0.2116 1.03 0.916 1.16 -0.108 0.166 0.513 0.29 0.897 0.649 1.24 -0.198 0.172 0.251 0.6008 0.82 0.585 1.15 0.046 0.17 0.787 0.1043 1.05 0.751 1.46 PRS_PLINK_0.00398107170553497 FALSE 557.1 Celiac disease Both 88 442 10 digestive chartreuse4 442, 88 111, 30 110, 17 110, 16 111, 25 -0.0348 0.12 0.771 0.1127 0.966 0.764 1.22 -0.6 0.34 0.078 1.108 0.549 0.282 1.07 -0.653 0.352 0.0635 1.197 0.52 0.261 1.04 -0.11 0.315 0.726 0.1389 0.896 0.484 1.66 PRS_PLINK_0.00398107170553497 FALSE 558 Noninfectious gastroenteritis Both 609 2176 10 digestive chartreuse4 2176, 609 544, 154 544, 180 544, 131 544, 144 -0.0179 0.048 0.709 0.1495 0.982 0.894 1.08 0.166 0.129 0.198 0.7028 1.18 0.917 1.52 -0.112 0.14 0.421 0.3757 0.894 0.68 1.18 0.0264 0.137 0.848 0.07172 1.03 0.784 1.34 PRS_PLINK_0.00398107170553497 FALSE 559 Ileostomy status Both 78 593 10 digestive chartreuse4 593, 78 149, 17 148, 13 148, 23 148, 25 0.175 0.125 0.16 0.7969 1.19 0.933 1.52 -0.348 0.374 0.353 0.4526 0.706 0.339 1.47 0.215 0.336 0.523 0.2818 1.24 0.641 2.4 0.315 0.333 0.344 0.4635 1.37 0.713 2.63 PRS_PLINK_0.00398107170553497 FALSE 560 Intestinal obstruction without mention of hernia Both 387 1868 10 digestive chartreuse4 1868, 387 467, 103 467, 96 467, 98 467, 90 -0.0406 0.0579 0.483 0.3162 0.96 0.857 1.08 -0.0874 0.16 0.586 0.2323 0.916 0.669 1.25 -0.0387 0.162 0.811 0.09072 0.962 0.7 1.32 -0.157 0.167 0.348 0.4581 0.855 0.616 1.19 PRS_PLINK_0.00398107170553497 FALSE 560.1 Paralytic ileus Both 161 1005 10 digestive chartreuse4 1005, 161 252, 42 251, 40 251, 40 251, 39 -0.0199 0.0868 0.819 0.0869 0.98 0.827 1.16 -0.0181 0.239 0.94 0.02699 0.982 0.615 1.57 0.0179 0.241 0.941 0.02655 1.02 0.635 1.63 -0.0512 0.249 0.837 0.07729 0.95 0.583 1.55 PRS_PLINK_0.00398107170553497 FALSE 560.2 Impaction of intestine Both 83 394 10 digestive chartreuse4 394, 83 99, 15 98, 24 98, 25 99, 19 0.0272 0.126 0.829 0.08149 1.03 0.803 1.32 0.546 0.368 0.139 0.8582 1.73 0.838 3.55 0.498 0.359 0.166 0.7791 1.64 0.813 3.33 0.127 0.377 0.736 0.1329 1.14 0.543 2.37 PRS_PLINK_0.00398107170553497 FALSE 560.3 Peritoneal or intestinal adhesions Both 45 207 10 digestive chartreuse4 207, 45 52, 17 52, 11 51, 7 52, 10 -0.214 0.175 0.223 0.6509 0.808 0.573 1.14 -0.426 0.444 0.338 0.4715 0.653 0.274 1.56 -0.966 0.523 0.0649 1.188 0.381 0.136 1.06 -0.63 0.471 0.181 0.7419 0.533 0.211 1.34 PRS_PLINK_0.00398107170553497 TRUE 560.4 Other intestinal obstruction Both 227 1227 10 digestive chartreuse4 1227, 227 307, 65 307, 53 306, 55 307, 54 -0.0587 0.0769 0.445 0.3515 0.943 0.811 1.1 -0.197 0.205 0.337 0.473 0.821 0.55 1.23 -0.222 0.207 0.283 0.5486 0.801 0.534 1.2 -0.215 0.209 0.303 0.5188 0.806 0.535 1.21 PRS_PLINK_0.00398107170553497 FALSE 561 Symptoms involving digestive system Both 548 1970 10 digestive chartreuse4 1970, 548 493, 136 492, 134 492, 135 493, 143 0.0299 0.0506 0.554 0.2563 1.03 0.933 1.14 -0.063 0.141 0.656 0.1834 0.939 0.712 1.24 -0.0178 0.143 0.901 0.04548 0.982 0.743 1.3 0.0585 0.143 0.682 0.1661 1.06 0.801 1.4 PRS_PLINK_0.00398107170553497 FALSE 562 Diverticulosis and diverticulitis Both 1305 1897 10 digestive chartreuse4 1897, 1305 475, 293 474, 313 474, 351 474, 348 0.056 0.041 0.172 0.7653 1.06 0.976 1.15 0.0132 0.115 0.909 0.04153 1.01 0.809 1.27 0.147 0.114 0.198 0.7043 1.16 0.926 1.45 0.144 0.116 0.212 0.6734 1.16 0.921 1.45 PRS_PLINK_0.00398107170553497 FALSE 562.1 Diverticulosis Both 1299 1885 10 digestive chartreuse4 1885, 1299 472, 292 471, 312 471, 350 471, 345 0.0552 0.0411 0.18 0.7459 1.06 0.975 1.15 0.0065 0.115 0.955 0.02002 1.01 0.803 1.26 0.154 0.115 0.18 0.7455 1.17 0.932 1.46 0.14 0.116 0.228 0.6417 1.15 0.916 1.44 PRS_PLINK_0.00398107170553497 FALSE 562.2 Diverticulitis Both 238 1227 10 digestive chartreuse4 1227, 238 307, 58 307, 60 306, 64 307, 56 -0.0162 0.0746 0.828 0.08193 0.984 0.85 1.14 -0.0121 0.206 0.953 0.02081 0.988 0.66 1.48 0.0773 0.205 0.706 0.151 1.08 0.723 1.62 -0.0145 0.216 0.946 0.02396 0.986 0.646 1.5 PRS_PLINK_0.00398107170553497 FALSE 564 Functional digestive disorders Both 1871 2279 10 digestive chartreuse4 2279, 1871 570, 448 570, 497 569, 477 570, 448 0.0364 0.0332 0.273 0.5645 1.04 0.972 1.11 0.0883 0.0922 0.339 0.4703 1.09 0.912 1.31 0.0837 0.0944 0.375 0.4258 1.09 0.904 1.31 0.0598 0.0958 0.533 0.2735 1.06 0.88 1.28 PRS_PLINK_0.00398107170553497 FALSE 564.1 Irritable Bowel Syndrome Both 700 2049 10 digestive chartreuse4 2049, 700 513, 176 512, 179 512, 171 512, 174 0.0213 0.0456 0.64 0.1941 1.02 0.934 1.12 0.00788 0.127 0.95 0.0221 1.01 0.786 1.29 0.00957 0.129 0.941 0.0264 1.01 0.783 1.3 0.0224 0.131 0.865 0.0632 1.02 0.791 1.32 PRS_PLINK_0.00398107170553497 FALSE 564.9 Personal history of diseases of digestive system Both 495 2025 10 digestive chartreuse4 2025, 495 507, 111 506, 144 506, 131 506, 109 0.0168 0.0528 0.751 0.1246 1.02 0.917 1.13 0.245 0.144 0.0899 1.046 1.28 0.963 1.69 0.208 0.15 0.165 0.7832 1.23 0.918 1.65 0.0299 0.155 0.847 0.07193 1.03 0.76 1.4 PRS_PLINK_0.00398107170553497 FALSE 565 Anal and rectal conditions Both 684 2992 10 digestive chartreuse4 2992, 684 747, 169 748, 170 748, 171 748, 174 0.00198 0.0442 0.964 0.01583 1 0.919 1.09 -0.0238 0.122 0.845 0.0729 0.976 0.768 1.24 -0.015 0.124 0.904 0.04399 0.985 0.773 1.26 -0.0401 0.126 0.75 0.1251 0.961 0.751 1.23 PRS_PLINK_0.00398107170553497 FALSE 565.1 Anal and rectal polyp Both 307 1275 10 digestive chartreuse4 1275, 307 318, 82 319, 83 318, 72 319, 70 -0.0993 0.0665 0.135 0.8681 0.906 0.795 1.03 -0.0176 0.178 0.921 0.03557 0.983 0.693 1.39 -0.185 0.185 0.317 0.4983 0.831 0.579 1.19 -0.205 0.191 0.284 0.5469 0.815 0.56 1.19 PRS_PLINK_0.00398107170553497 FALSE 567 Peritonitis and retroperitoneal infections Both 177 1106 10 digestive chartreuse4 1106, 177 276, 47 276, 37 276, 43 277, 50 -0.0105 0.0796 0.895 0.04835 0.99 0.847 1.16 -0.268 0.236 0.256 0.5924 0.765 0.482 1.21 -0.174 0.233 0.455 0.3419 0.84 0.533 1.33 0.00559 0.225 0.98 0.00867 1.01 0.646 1.56 PRS_PLINK_0.00398107170553497 FALSE 568 Other disorders of peritoneum Both 165 1501 10 digestive chartreuse4 1501, 165 375, 47 375, 40 375, 40 375, 38 -0.0944 0.0858 0.271 0.5668 0.91 0.769 1.08 -0.218 0.228 0.339 0.4704 0.804 0.515 1.26 -0.203 0.233 0.382 0.4178 0.816 0.517 1.29 -0.295 0.238 0.215 0.6673 0.744 0.467 1.19 PRS_PLINK_0.00398107170553497 FALSE 568.1 Peritoneal adhesions (postoperative) (postinfection) Both 109 1104 10 digestive chartreuse4 1104, 109 275, 33 276, 23 276, 28 276, 25 -0.121 0.102 0.237 0.625 0.886 0.725 1.08 -0.382 0.282 0.175 0.7568 0.682 0.393 1.19 -0.21 0.272 0.441 0.3557 0.811 0.476 1.38 -0.394 0.284 0.166 0.7809 0.674 0.386 1.18 PRS_PLINK_0.00398107170553497 FALSE 569 Other disorders of intestine Both 1359 3341 10 digestive chartreuse4 3341, 1359 835, 335 835, 338 835, 328 835, 358 0.0312 0.034 0.358 0.4464 1.03 0.965 1.1 -0.0216 0.0948 0.82 0.08628 0.979 0.813 1.18 -0.0228 0.0961 0.813 0.09017 0.977 0.81 1.18 0.0731 0.0959 0.446 0.3505 1.08 0.891 1.3 PRS_PLINK_0.00398107170553497 FALSE 569.1 Toxic gastroenteritis and colitis Both 40 324 10 digestive chartreuse4 324, 40 81, 9 81, 12 81, 11 81, 8 -0.0779 0.169 0.645 0.1905 0.925 0.664 1.29 0.186 0.474 0.694 0.1586 1.2 0.476 3.05 0.131 0.463 0.776 0.11 1.14 0.461 2.82 -0.0808 0.496 0.871 0.06018 0.922 0.349 2.44 PRS_PLINK_0.00398107170553497 TRUE 569.2 Gastrointestinal complications Both 161 1257 10 digestive chartreuse4 1257, 161 315, 51 314, 34 314, 30 314, 46 -0.0707 0.0862 0.412 0.3851 0.932 0.787 1.1 -0.39 0.234 0.0948 1.023 0.677 0.428 1.07 -0.536 0.245 0.0286 1.543 0.585 0.362 0.946 -0.132 0.225 0.556 0.2549 0.876 0.564 1.36 PRS_PLINK_0.00398107170553497 FALSE 571 Chronic liver disease and cirrhosis Both 507 3317 10 digestive chartreuse4 3317, 507 830, 131 829, 137 829, 111 829, 128 -0.0622 0.0493 0.207 0.684 0.94 0.853 1.03 0.0384 0.133 0.773 0.1121 1.04 0.801 1.35 -0.19 0.141 0.18 0.7457 0.827 0.627 1.09 -0.0549 0.139 0.694 0.1588 0.947 0.72 1.24 PRS_PLINK_0.00398107170553497 FALSE 571.5 Other chronic nonalcoholic liver disease Both 481 3292 10 digestive chartreuse4 3292, 481 823, 125 823, 130 823, 105 823, 121 -0.0717 0.0504 0.155 0.8095 0.931 0.843 1.03 0.022 0.136 0.872 0.05971 1.02 0.783 1.33 -0.192 0.145 0.185 0.7327 0.826 0.622 1.1 -0.0673 0.142 0.637 0.1961 0.935 0.707 1.24 PRS_PLINK_0.00398107170553497 FALSE 571.51 Cirrhosis of liver without mention of alcohol Both 92 967 10 digestive chartreuse4 967, 92 242, 27 242, 20 241, 20 242, 25 -0.128 0.112 0.255 0.5931 0.88 0.706 1.1 -0.361 0.304 0.235 0.629 0.697 0.385 1.26 -0.365 0.311 0.24 0.619 0.694 0.377 1.28 -0.148 0.304 0.628 0.2022 0.863 0.475 1.57 PRS_PLINK_0.00398107170553497 FALSE 571.6 Primary biliary cirrhosis Both 17 188 10 digestive chartreuse4 188, 17 47, 3 47, 3 47, 5 47, 6 0.0566 0.257 0.826 0.08317 1.06 0.64 1.75 0.00888 0.713 0.99 0.004336 1.01 0.249 4.08 0.589 0.759 0.438 0.3589 1.8 0.407 7.98 1.8 1.02 0.0758 1.12 6.07 0.829 44.4 PRS_PLINK_0.00398107170553497 TRUE 571.8 Liver abscess and sequelae of chronic liver disease Both 85 877 10 digestive chartreuse4 877, 85 220, 20 219, 26 219, 14 219, 25 -0.0737 0.12 0.539 0.2687 0.929 0.734 1.18 0.197 0.31 0.526 0.2794 1.22 0.663 2.23 -0.382 0.371 0.302 0.5193 0.682 0.33 1.41 0.148 0.33 0.655 0.1839 1.16 0.607 2.21 PRS_PLINK_0.00398107170553497 FALSE 571.81 Portal hypertension Both 46 539 10 digestive chartreuse4 539, 46 135, 10 135, 15 134, 12 135, 9 -0.217 0.158 0.169 0.7723 0.805 0.59 1.1 0.322 0.408 0.43 0.3667 1.38 0.62 3.07 0.035 0.452 0.938 0.0277 1.04 0.427 2.51 -0.101 0.484 0.835 0.0784 0.904 0.35 2.33 PRS_PLINK_0.00398107170553497 TRUE 572 Ascites (non malignant) Both 271 2243 10 digestive chartreuse4 2243, 271 561, 75 561, 56 560, 70 561, 70 -0.0941 0.0659 0.154 0.8136 0.91 0.8 1.04 -0.291 0.186 0.117 0.9308 0.748 0.519 1.08 -0.107 0.182 0.557 0.2539 0.898 0.628 1.28 -0.0895 0.185 0.628 0.2021 0.914 0.637 1.31 PRS_PLINK_0.00398107170553497 FALSE 573 Other disorders of liver Both 722 3446 10 digestive chartreuse4 3446, 722 862, 183 861, 191 861, 174 862, 174 -0.0547 0.0428 0.201 0.6964 0.947 0.871 1.03 0.0186 0.116 0.872 0.05928 1.02 0.812 1.28 -0.0595 0.12 0.62 0.2079 0.942 0.745 1.19 -0.0906 0.122 0.458 0.3389 0.913 0.719 1.16 PRS_PLINK_0.00398107170553497 FALSE 573.1 Chronic passive congestion of liver Both 13 108 10 digestive chartreuse4 108, 13 27, 4 27, 6 27, 3 27, 0 -0.478 0.299 0.109 0.9627 0.62 0.345 1.11 0.654 0.785 0.404 0.3932 1.92 0.413 8.95 0.081 0.817 0.921 0.03572 1.08 0.219 5.37 -2.4 1.42 0.0899 1.046 0.0905 0.00563 1.45 PRS_PLINK_0.00398107170553497 TRUE 573.2 Liver replaced by transplant Both 43 240 10 digestive chartreuse4 240, 43 60, 12 60, 10 60, 7 60, 14 -0.0874 0.181 0.629 0.2014 0.916 0.643 1.31 -0.0548 0.464 0.906 0.04289 0.947 0.381 2.35 -0.706 0.533 0.185 0.7317 0.493 0.173 1.4 -0.129 0.465 0.781 0.1073 0.879 0.353 2.19 PRS_PLINK_0.00398107170553497 TRUE 573.3 Hepatomegaly Both 52 506 10 digestive chartreuse4 506, 52 127, 13 126, 14 126, 15 127, 10 -0.107 0.152 0.481 0.3178 0.898 0.666 1.21 0.0134 0.391 0.973 0.01205 1.01 0.471 2.18 0.0749 0.399 0.851 0.06996 1.08 0.493 2.36 -0.264 0.427 0.537 0.2703 0.768 0.333 1.77 PRS_PLINK_0.00398107170553497 FALSE 573.4 Acute and subacute necrosis of liver Both 42 284 10 digestive chartreuse4 284, 42 71, 14 71, 15 71, 3 71, 10 -0.164 0.176 0.351 0.4543 0.848 0.6 1.2 0.0303 0.419 0.942 0.02578 1.03 0.453 2.34 -1.69 0.694 0.0152 1.819 0.185 0.0475 0.722 -0.373 0.467 0.425 0.3717 0.689 0.276 1.72 PRS_PLINK_0.00398107170553497 TRUE 573.5 Jaundice (not of newborn) Both 126 869 10 digestive chartreuse4 869, 126 218, 26 217, 26 217, 39 217, 35 0.0924 0.0977 0.344 0.463 1.1 0.906 1.33 0.0185 0.293 0.95 0.0225 1.02 0.574 1.81 0.424 0.275 0.123 0.911 1.53 0.892 2.62 0.313 0.287 0.276 0.5597 1.37 0.779 2.4 PRS_PLINK_0.00398107170553497 FALSE 573.6 Nonspecific elevation of levels of transaminase or lactic acid dehydrogenase [LDH] Both 467 2683 10 digestive chartreuse4 2683, 467 671, 107 671, 121 670, 114 671, 125 -0.00188 0.0515 0.971 0.01281 0.998 0.902 1.1 0.0844 0.144 0.559 0.2528 1.09 0.82 1.44 -0.000943 0.148 0.995 0.002211 0.999 0.747 1.34 0.137 0.148 0.352 0.453 1.15 0.859 1.53 PRS_PLINK_0.00398107170553497 FALSE 573.7 Abnormal results of function study of liver Both 524 2906 10 digestive chartreuse4 2906, 524 727, 134 726, 133 726, 120 727, 137 -0.046 0.0484 0.342 0.4661 0.955 0.869 1.05 -0.0566 0.135 0.674 0.1714 0.945 0.726 1.23 -0.192 0.14 0.171 0.767 0.826 0.628 1.09 -0.0125 0.137 0.927 0.03282 0.988 0.755 1.29 PRS_PLINK_0.00398107170553497 FALSE 573.9 Abnormal serum enzyme levels Both 787 3454 10 digestive chartreuse4 3454, 787 864, 187 863, 207 863, 190 864, 202 -0.0372 0.0406 0.359 0.4447 0.963 0.89 1.04 0.0666 0.114 0.557 0.2538 1.07 0.856 1.34 -0.0237 0.117 0.84 0.07583 0.977 0.776 1.23 0.0627 0.117 0.592 0.2276 1.06 0.846 1.34 PRS_PLINK_0.00398107170553497 FALSE 574 Cholelithiasis and cholecystitis Both 468 3627 10 digestive chartreuse4 3627, 468 907, 108 907, 117 906, 107 907, 136 0.0938 0.05 0.0608 1.216 1.1 0.996 1.21 0.114 0.142 0.42 0.3764 1.12 0.849 1.48 0.0185 0.147 0.9 0.04575 1.02 0.763 1.36 0.263 0.142 0.0637 1.196 1.3 0.985 1.72 PRS_PLINK_0.00398107170553497 FALSE 574.1 Cholelithiasis Both 437 3472 10 digestive chartreuse4 3472, 437 868, 101 868, 109 868, 99 868, 128 0.101 0.0515 0.0494 1.306 1.11 1 1.22 0.114 0.147 0.437 0.3591 1.12 0.84 1.5 0.0154 0.153 0.92 0.03641 1.02 0.753 1.37 0.264 0.146 0.0712 1.148 1.3 0.978 1.73 PRS_PLINK_0.00398107170553497 FALSE 574.11 Cholelithiasis with acute cholecystitis Both 55 404 10 digestive chartreuse4 404, 55 101, 12 101, 11 101, 17 101, 15 0.176 0.149 0.238 0.623 1.19 0.89 1.6 -0.0414 0.422 0.922 0.03537 0.959 0.42 2.19 0.313 0.398 0.432 0.365 1.37 0.627 2.98 0.267 0.411 0.517 0.2866 1.31 0.583 2.92 PRS_PLINK_0.00398107170553497 FALSE 574.12 Cholelithiasis with other cholecystitis Both 83 658 10 digestive chartreuse4 658, 83 165, 15 164, 21 164, 18 165, 29 0.193 0.117 0.097 1.013 1.21 0.966 1.52 0.389 0.354 0.273 0.5645 1.48 0.737 2.95 0.101 0.371 0.785 0.1053 1.11 0.535 2.29 0.741 0.346 0.0324 1.489 2.1 1.06 4.14 PRS_PLINK_0.00398107170553497 FALSE 574.2 Calculus of bile duct Both 149 968 10 digestive chartreuse4 968, 149 242, 38 242, 24 242, 43 242, 44 0.022 0.0918 0.811 0.09113 1.02 0.854 1.22 -0.415 0.278 0.135 0.8694 0.66 0.383 1.14 0.0707 0.244 0.772 0.1123 1.07 0.665 1.73 0.12 0.251 0.631 0.1998 1.13 0.69 1.84 PRS_PLINK_0.00398107170553497 FALSE 574.3 Cholecystitis without cholelithiasis Both 120 967 10 digestive chartreuse4 967, 120 242, 24 242, 33 241, 27 242, 36 0.142 0.0977 0.147 0.8336 1.15 0.952 1.4 0.366 0.279 0.19 0.7207 1.44 0.834 2.49 0.118 0.297 0.692 0.1596 1.12 0.628 2.01 0.467 0.284 0.0998 1.001 1.59 0.915 2.78 PRS_PLINK_0.00398107170553497 FALSE 575 Other biliary tract disease Both 344 2636 10 digestive chartreuse4 2636, 344 659, 81 659, 91 659, 81 659, 90 -0.0181 0.0591 0.76 0.1194 0.982 0.875 1.1 0.144 0.163 0.379 0.4214 1.15 0.838 1.59 -0.0165 0.171 0.923 0.03472 0.984 0.703 1.38 0.142 0.168 0.399 0.3985 1.15 0.829 1.6 PRS_PLINK_0.00398107170553497 FALSE 575.1 Cholangitis Both 42 354 10 digestive chartreuse4 354, 42 89, 10 88, 7 88, 12 89, 13 0.058 0.166 0.727 0.1382 1.06 0.765 1.47 -0.493 0.506 0.33 0.4819 0.611 0.227 1.65 0.115 0.45 0.798 0.09773 1.12 0.464 2.71 0.346 0.454 0.445 0.3514 1.41 0.581 3.44 PRS_PLINK_0.00398107170553497 TRUE 575.2 Obstruction of bile duct Both 75 651 10 digestive chartreuse4 651, 75 163, 19 163, 22 162, 12 163, 22 -0.0305 0.127 0.81 0.09142 0.97 0.756 1.24 0.145 0.34 0.669 0.1749 1.16 0.594 2.25 -0.402 0.392 0.305 0.5157 0.669 0.31 1.44 0.208 0.338 0.537 0.2701 1.23 0.636 2.39 PRS_PLINK_0.00398107170553497 FALSE 575.6 Cholesterolosis of gallbladder Both 34 250 10 digestive chartreuse4 250, 34 63, 9 62, 8 62, 11 63, 6 0.0672 0.17 0.692 0.1601 1.07 0.767 1.49 -0.277 0.524 0.597 0.224 0.758 0.271 2.12 0.491 0.489 0.315 0.5023 1.63 0.627 4.26 -0.258 0.514 0.616 0.2106 0.773 0.282 2.12 PRS_PLINK_0.00398107170553497 TRUE 575.7 Other disorders of gallbladder Both 151 1175 10 digestive chartreuse4 1175, 151 294, 36 294, 48 293, 27 294, 40 -0.0426 0.091 0.639 0.1942 0.958 0.802 1.15 0.347 0.238 0.144 0.841 1.41 0.888 2.25 -0.368 0.274 0.179 0.7468 0.692 0.404 1.18 0.157 0.251 0.532 0.274 1.17 0.715 1.92 PRS_PLINK_0.00398107170553497 FALSE 575.8 Other disorders of biliary tract Both 168 1291 10 digestive chartreuse4 1291, 168 323, 42 323, 40 322, 35 323, 50 -0.0476 0.0847 0.575 0.2406 0.954 0.808 1.13 -0.0103 0.238 0.965 0.01528 0.99 0.62 1.58 -0.118 0.25 0.638 0.1952 0.889 0.544 1.45 0.237 0.231 0.305 0.5159 1.27 0.806 1.99 PRS_PLINK_0.00398107170553497 FALSE 575.9 Nonspecific abnormal findings on radiological and other examination of biliary tract Both 40 298 10 digestive chartreuse4 298, 40 75, 7 74, 7 74, 12 75, 14 0.157 0.184 0.394 0.404 1.17 0.816 1.68 0.0611 0.527 0.908 0.04208 1.06 0.378 2.99 0.489 0.488 0.316 0.4999 1.63 0.626 4.25 0.53 0.477 0.267 0.5728 1.7 0.666 4.33 PRS_PLINK_0.00398107170553497 TRUE 577 Diseases of pancreas Both 288 2617 10 digestive chartreuse4 2617, 288 655, 69 654, 83 654, 61 654, 74 -0.0494 0.0649 0.446 0.3508 0.952 0.838 1.08 0.157 0.172 0.363 0.4406 1.17 0.835 1.64 -0.169 0.188 0.367 0.4348 0.845 0.585 1.22 0.0687 0.183 0.707 0.1503 1.07 0.748 1.53 PRS_PLINK_0.00398107170553497 FALSE 577.1 Acute pancreatitis Both 160 1399 10 digestive chartreuse4 1399, 160 350, 36 350, 49 349, 35 350, 39 -0.128 0.0858 0.135 0.87 0.88 0.743 1.04 0.266 0.232 0.252 0.5983 1.3 0.828 2.06 -0.0904 0.255 0.723 0.1408 0.914 0.554 1.51 0.0367 0.25 0.883 0.05385 1.04 0.635 1.69 PRS_PLINK_0.00398107170553497 FALSE 577.2 Chronic pancreatitis Both 64 538 10 digestive chartreuse4 538, 64 135, 13 134, 24 134, 13 135, 14 -0.12 0.136 0.378 0.4225 0.887 0.68 1.16 0.648 0.373 0.0824 1.084 1.91 0.92 3.97 0.0248 0.414 0.952 0.02124 1.03 0.455 2.31 0.0899 0.407 0.825 0.0835 1.09 0.493 2.43 PRS_PLINK_0.00398107170553497 FALSE 577.3 Cyst and pseudocyst of pancreas Both 83 711 10 digestive chartreuse4 711, 83 178, 22 178, 17 177, 18 178, 26 -0.0436 0.124 0.725 0.1399 0.957 0.751 1.22 -0.268 0.342 0.432 0.3641 0.765 0.391 1.49 -0.148 0.34 0.662 0.179 0.862 0.443 1.68 0.163 0.326 0.617 0.21 1.18 0.622 2.23 PRS_PLINK_0.00398107170553497 FALSE 578 Gastrointestinal hemorrhage Both 800 3660 10 digestive chartreuse4 3660, 800 914, 192 915, 199 915, 202 915, 207 0.00538 0.0404 0.894 0.04867 1.01 0.929 1.09 0.0159 0.113 0.888 0.05157 1.02 0.815 1.27 0.0312 0.114 0.785 0.105 1.03 0.825 1.29 0.0477 0.115 0.678 0.1689 1.05 0.837 1.31 PRS_PLINK_0.00398107170553497 FALSE 578.1 Hematemesis Both 69 468 10 digestive chartreuse4 468, 69 117, 13 117, 20 117, 14 117, 22 0.0919 0.129 0.476 0.3228 1.1 0.852 1.41 0.413 0.372 0.268 0.5721 1.51 0.728 3.14 0.0276 0.395 0.944 0.02486 1.03 0.474 2.23 0.417 0.38 0.272 0.565 1.52 0.72 3.2 PRS_PLINK_0.00398107170553497 FALSE 578.2 Blood in stool Both 494 2687 10 digestive chartreuse4 2687, 494 672, 114 672, 132 671, 117 672, 131 0.00967 0.0503 0.848 0.07185 1.01 0.915 1.11 0.141 0.141 0.316 0.4999 1.15 0.874 1.52 0.00531 0.146 0.971 0.01278 1.01 0.755 1.34 0.132 0.144 0.362 0.4412 1.14 0.86 1.51 PRS_PLINK_0.00398107170553497 FALSE 578.8 Hemorrhage of rectum and anus Both 429 2250 10 digestive chartreuse4 2250, 429 562, 117 562, 93 562, 114 563, 105 -0.000442 0.0537 0.993 0.002859 1 0.9 1.11 -0.232 0.152 0.127 0.8946 0.793 0.588 1.07 -0.0487 0.149 0.744 0.1286 0.952 0.711 1.28 -0.111 0.153 0.468 0.3301 0.895 0.662 1.21 PRS_PLINK_0.00398107170553497 FALSE 578.9 Hemorrhage of gastrointestinal tract Both 215 1461 10 digestive chartreuse4 1461, 215 366, 48 365, 54 365, 54 365, 59 0.0209 0.0732 0.775 0.1105 1.02 0.885 1.18 0.0992 0.212 0.64 0.1936 1.1 0.728 1.67 0.0463 0.214 0.829 0.08158 1.05 0.689 1.59 0.154 0.212 0.467 0.3309 1.17 0.771 1.77 PRS_PLINK_0.00398107170553497 FALSE 579 Other symptoms involving abdomen and pelvis Both 694 3481 10 digestive chartreuse4 3481, 694 870, 160 870, 165 870, 193 870, 176 0.0246 0.0428 0.566 0.2475 1.02 0.942 1.11 0.0134 0.122 0.913 0.03971 1.01 0.797 1.29 0.177 0.121 0.143 0.8455 1.19 0.942 1.51 0.106 0.124 0.393 0.4056 1.11 0.872 1.42 PRS_PLINK_0.00398107170553497 FALSE 579.2 Splenomegaly Both 62 654 10 digestive chartreuse4 654, 62 164, 14 163, 17 163, 17 164, 14 0.0364 0.141 0.797 0.09873 1.04 0.786 1.37 0.159 0.372 0.669 0.1743 1.17 0.565 2.43 0.317 0.373 0.396 0.4023 1.37 0.66 2.85 0.106 0.412 0.797 0.09854 1.11 0.496 2.49 PRS_PLINK_0.00398107170553497 FALSE 579.8 Nonspecific abnormal findings in stool contents Both 307 1541 10 digestive chartreuse4 1541, 307 386, 72 385, 81 385, 76 385, 78 0.017 0.0635 0.789 0.1031 1.02 0.898 1.15 0.0735 0.18 0.684 0.1652 1.08 0.756 1.53 -0.0356 0.182 0.845 0.07313 0.965 0.676 1.38 0.0367 0.183 0.841 0.0751 1.04 0.725 1.49 PRS_PLINK_0.00398107170553497 FALSE 580 Nephritis; nephrosis; renal sclerosis Both 270 1671 11 genitourinary black 1671, 270 418, 68 418, 61 417, 79 418, 62 0.00834 0.066 0.899 0.04603 1.01 0.886 1.15 -0.0341 0.192 0.859 0.06607 0.967 0.664 1.41 0.216 0.184 0.241 0.6172 1.24 0.865 1.78 -0.0287 0.194 0.883 0.0542 0.972 0.664 1.42 PRS_PLINK_0.00398107170553497 FALSE 580.1 Glomerulonephritis Both 71 398 11 genitourinary black 398, 71 100, 13 99, 22 99, 20 100, 16 0.0241 0.131 0.854 0.06859 1.02 0.792 1.32 0.551 0.385 0.153 0.8166 1.74 0.815 3.69 0.694 0.428 0.105 0.9772 2 0.864 4.63 0.00667 0.44 0.988 0.005283 1.01 0.425 2.38 PRS_PLINK_0.00398107170553497 FALSE 580.11 Proliferative glomerulonephritis Both 29 133 11 genitourinary black 133, 29 34, 8 33, 7 33, 9 33, 5 0.00526 0.213 0.98 0.008663 1.01 0.663 1.53 -0.212 0.668 0.751 0.1244 0.809 0.218 3 0.472 0.641 0.461 0.336 1.6 0.457 5.63 -0.545 0.744 0.463 0.334 0.58 0.135 2.49 PRS_PLINK_0.00398107170553497 TRUE 580.12 Non-proliferative glomerulonephritis Both 17 92 11 genitourinary black 92, 17 23, 6 23, 5 23, 5 23, 1 -0.517 0.289 0.074 1.131 0.596 0.338 1.05 -0.263 0.777 0.735 0.1339 0.769 0.168 3.52 -0.13 0.703 0.853 0.06914 0.878 0.221 3.48 -1.14 0.956 0.233 0.6332 0.319 0.049 2.08 PRS_PLINK_0.00398107170553497 TRUE 580.13 Acute glomerulonephritis, NOS Both 11 59 11 genitourinary black 59, 11 15, 5 15, 4 14, 2 15, 0 -0.697 0.413 0.0913 1.039 0.498 0.222 1.12 -0.787 1.12 0.484 0.3154 0.455 0.0503 4.12 -0.242 0.958 0.801 0.09653 0.785 0.12 5.14 -2.12 1.47 0.149 0.8266 0.12 0.00677 2.14 PRS_PLINK_0.00398107170553497 TRUE 580.14 Chronic glomerulonephritis, NOS Both 45 284 11 genitourinary black 284, 45 71, 8 71, 12 71, 16 71, 9 0.0529 0.16 0.742 0.1298 1.05 0.77 1.44 0.558 0.494 0.259 0.587 1.75 0.663 4.6 1.1 0.538 0.0414 1.383 2.99 1.04 8.58 0.183 0.536 0.733 0.1346 1.2 0.42 3.43 PRS_PLINK_0.00398107170553497 TRUE 580.2 Nephrotic syndrome without mention of glomerulonephritis Both 34 224 11 genitourinary black 224, 34 56, 14 56, 9 56, 8 56, 3 -0.579 0.204 0.0045 2.347 0.56 0.376 0.836 -0.504 0.476 0.29 0.5375 0.604 0.238 1.54 -0.441 0.522 0.398 0.4002 0.643 0.232 1.79 -1.44 0.668 0.0314 1.503 0.238 0.0643 0.88 PRS_PLINK_0.00398107170553497 TRUE 580.3 Nephritis and nephropathy without mention of glomerulonephritis Both 220 1310 11 genitourinary black 1310, 220 328, 55 327, 45 327, 66 328, 54 0.04 0.0729 0.583 0.2341 1.04 0.902 1.2 -0.07 0.219 0.75 0.1251 0.932 0.607 1.43 0.245 0.204 0.23 0.6376 1.28 0.856 1.9 0.0512 0.214 0.811 0.09108 1.05 0.692 1.6 PRS_PLINK_0.00398107170553497 FALSE 580.31 Nephritis and nephropathy in diseases classified elsewhere Both 139 858 11 genitourinary black 858, 139 215, 33 214, 26 214, 38 215, 42 0.158 0.0916 0.0849 1.071 1.17 0.979 1.4 -0.134 0.282 0.636 0.1967 0.875 0.504 1.52 0.199 0.262 0.446 0.3503 1.22 0.731 2.04 0.311 0.262 0.236 0.6279 1.36 0.817 2.28 PRS_PLINK_0.00398107170553497 FALSE 580.32 Nephritis and nephropathy with pathological lesion Both 111 732 11 genitourinary black 732, 111 183, 28 183, 23 183, 34 183, 26 0.0227 0.102 0.824 0.08417 1.02 0.838 1.25 -0.037 0.306 0.904 0.04388 0.964 0.529 1.76 0.227 0.289 0.433 0.3636 1.25 0.712 2.21 -0.089 0.3 0.767 0.1152 0.915 0.508 1.65 PRS_PLINK_0.00398107170553497 FALSE 580.4 Renal sclerosis, NOS Both 44 374 11 genitourinary black 374, 44 94, 10 93, 14 93, 12 94, 8 -0.0443 0.159 0.781 0.1074 0.957 0.7 1.31 0.554 0.439 0.208 0.6824 1.74 0.735 4.12 0.431 0.463 0.352 0.4535 1.54 0.621 3.81 -0.15 0.484 0.756 0.1213 0.861 0.333 2.22 PRS_PLINK_0.00398107170553497 TRUE 585 Renal failure Both 882 3416 11 genitourinary black 3416, 882 853, 198 854, 232 854, 240 854, 212 0.0205 0.0402 0.61 0.2144 1.02 0.943 1.1 0.122 0.113 0.279 0.5537 1.13 0.906 1.41 0.165 0.112 0.141 0.8519 1.18 0.947 1.47 0.0502 0.117 0.667 0.1762 1.05 0.837 1.32 PRS_PLINK_0.00398107170553497 FALSE 585.1 Acute renal failure Both 486 2788 11 genitourinary black 2788, 486 696, 120 697, 125 697, 134 697, 107 -0.0634 0.0512 0.216 0.6652 0.939 0.849 1.04 0.0483 0.141 0.732 0.1355 1.05 0.796 1.38 0.0734 0.141 0.602 0.2202 1.08 0.816 1.42 -0.133 0.149 0.373 0.4279 0.875 0.653 1.17 PRS_PLINK_0.00398107170553497 FALSE 585.2 Renal failure NOS Both 111 836 11 genitourinary black 836, 111 209, 23 209, 23 209, 31 209, 34 0.163 0.104 0.119 0.9244 1.18 0.959 1.44 -0.0141 0.305 0.963 0.01629 0.986 0.543 1.79 0.221 0.295 0.454 0.343 1.25 0.699 2.23 0.48 0.295 0.103 0.9867 1.62 0.907 2.88 PRS_PLINK_0.00398107170553497 FALSE 585.3 Chronic renal failure [CKD] Both 682 3153 11 genitourinary black 3153, 682 788, 142 788, 182 788, 186 788, 172 0.0782 0.0446 0.0796 1.099 1.08 0.991 1.18 0.245 0.128 0.0552 1.258 1.28 0.995 1.64 0.283 0.127 0.026 1.586 1.33 1.03 1.7 0.216 0.131 0.0994 1.003 1.24 0.96 1.6 PRS_PLINK_0.00398107170553497 FALSE 585.31 Renal dialysis Both 95 759 11 genitourinary black 759, 95 189, 18 190, 28 189, 26 190, 23 0.034 0.11 0.758 0.1204 1.03 0.833 1.28 0.334 0.319 0.295 0.53 1.4 0.747 2.61 0.282 0.333 0.397 0.4016 1.33 0.69 2.55 -0.0269 0.351 0.939 0.02738 0.973 0.489 1.94 PRS_PLINK_0.00398107170553497 FALSE 585.32 End stage renal disease Both 153 955 11 genitourinary black 955, 153 239, 34 239, 43 238, 43 239, 33 0.00173 0.0887 0.984 0.006814 1 0.842 1.19 0.26 0.248 0.294 0.5313 1.3 0.798 2.11 0.211 0.258 0.414 0.3835 1.23 0.745 2.05 -0.159 0.274 0.561 0.2509 0.853 0.499 1.46 PRS_PLINK_0.00398107170553497 FALSE 585.33 Chronic Kidney Disease, Stage III Both 412 2290 11 genitourinary black 2290, 412 572, 76 572, 109 572, 116 573, 111 0.126 0.056 0.0242 1.616 1.13 1.02 1.27 0.394 0.165 0.0166 1.781 1.48 1.07 2.05 0.463 0.164 0.00466 2.331 1.59 1.15 2.19 0.408 0.167 0.0146 1.835 1.5 1.08 2.09 PRS_PLINK_0.00398107170553497 FALSE 585.34 Chronic Kidney Disease, Stage IV Both 138 954 11 genitourinary black 954, 138 239, 28 238, 40 238, 39 239, 31 0.0841 0.0935 0.368 0.4338 1.09 0.906 1.31 0.395 0.264 0.135 0.8705 1.48 0.885 2.49 0.298 0.275 0.279 0.554 1.35 0.785 2.31 0.0651 0.286 0.82 0.08631 1.07 0.61 1.87 PRS_PLINK_0.00398107170553497 FALSE 585.4 Chronic kidney disease, Stage I or II Both 175 1202 11 genitourinary black 1202, 175 300, 48 300, 36 300, 42 301, 49 0.0618 0.0829 0.456 0.3411 1.06 0.904 1.25 -0.254 0.235 0.281 0.5512 0.776 0.489 1.23 -0.139 0.228 0.542 0.2658 0.87 0.556 1.36 0.0441 0.223 0.843 0.07405 1.05 0.675 1.62 PRS_PLINK_0.00398107170553497 FALSE 586 Other disorders of the kidney and ureters Both 1011 3563 11 genitourinary black 3563, 1011 890, 223 891, 268 890, 267 891, 253 0.0316 0.0374 0.398 0.4 1.03 0.959 1.11 0.176 0.106 0.0962 1.017 1.19 0.969 1.47 0.181 0.106 0.0869 1.061 1.2 0.974 1.48 0.0978 0.109 0.371 0.4303 1.1 0.89 1.37 PRS_PLINK_0.00398107170553497 FALSE 586.1 Anatomical abnormatilies of kidney and ureters Both 44 391 11 genitourinary black 391, 44 98, 11 98, 15 97, 9 98, 9 -0.07 0.155 0.651 0.1865 0.932 0.689 1.26 0.352 0.425 0.407 0.3906 1.42 0.619 3.27 -0.0506 0.455 0.911 0.04029 0.951 0.39 2.32 -0.13 0.455 0.776 0.1101 0.879 0.36 2.14 PRS_PLINK_0.00398107170553497 TRUE 586.11 Small kidney Both 25 243 11 genitourinary black 243, 25 61, 4 61, 8 60, 7 61, 6 0.116 0.206 0.574 0.241 1.12 0.75 1.68 0.823 0.602 0.172 0.7654 2.28 0.7 7.41 0.618 0.607 0.309 0.51 1.86 0.564 6.1 0.389 0.601 0.517 0.2864 1.48 0.455 4.79 PRS_PLINK_0.00398107170553497 TRUE 586.12 Vesicoureteral reflux Both 19 164 11 genitourinary black 164, 19 40, 7 41, 5 41, 3 41, 4 -0.193 0.245 0.43 0.3668 0.824 0.51 1.33 -0.344 0.646 0.595 0.2258 0.709 0.2 2.52 -0.659 0.658 0.317 0.4992 0.518 0.143 1.88 -0.582 0.674 0.388 0.4114 0.559 0.149 2.09 PRS_PLINK_0.00398107170553497 TRUE 586.2 Cyst of kidney, acquired Both 184 1275 11 genitourinary black 1275, 184 318, 39 319, 52 318, 45 319, 48 0.0301 0.0817 0.712 0.1472 1.03 0.878 1.21 0.33 0.228 0.148 0.8299 1.39 0.889 2.18 0.165 0.235 0.481 0.3176 1.18 0.745 1.87 0.175 0.237 0.462 0.335 1.19 0.748 1.9 PRS_PLINK_0.00398107170553497 FALSE 586.3 Vascular disorders of kidney/hypertrophy Both 24 167 11 genitourinary black 167, 24 42, 5 42, 7 41, 6 42, 6 0.184 0.253 0.468 0.33 1.2 0.731 1.98 0.39 0.577 0.499 0.3019 1.48 0.476 4.58 0.157 0.673 0.816 0.08834 1.17 0.313 4.37 0.412 0.64 0.52 0.2842 1.51 0.431 5.29 PRS_PLINK_0.00398107170553497 TRUE 586.4 Stricture/obstruction of ureter Both 153 1506 11 genitourinary black 1506, 153 377, 28 376, 46 376, 46 377, 33 -0.0218 0.0889 0.806 0.09368 0.978 0.822 1.16 0.499 0.249 0.0452 1.345 1.65 1.01 2.69 0.474 0.25 0.058 1.236 1.61 0.984 2.62 0.151 0.272 0.579 0.2375 1.16 0.682 1.98 PRS_PLINK_0.00398107170553497 FALSE 587 Kidney replaced by transpant Both 155 741 11 genitourinary black 741, 155 186, 41 185, 37 185, 40 185, 37 -0.0232 0.0924 0.802 0.09606 0.977 0.815 1.17 -0.0602 0.251 0.811 0.0911 0.942 0.575 1.54 -0.0823 0.257 0.749 0.1258 0.921 0.557 1.52 -0.272 0.265 0.304 0.5174 0.762 0.454 1.28 PRS_PLINK_0.00398107170553497 FALSE 588 Disorders resulting from impaired renal function Both 181 1017 11 genitourinary black 1017, 181 254, 46 254, 43 254, 53 254, 39 0.0122 0.0858 0.887 0.05186 1.01 0.855 1.2 -0.0216 0.233 0.926 0.03328 0.979 0.62 1.54 0.239 0.229 0.298 0.5257 1.27 0.81 1.99 -0.0688 0.243 0.777 0.1093 0.934 0.579 1.5 PRS_PLINK_0.00398107170553497 FALSE 588.1 Renal osteodystrophy Both 60 243 11 genitourinary black 243, 60 61, 23 61, 12 60, 10 61, 15 -0.0889 0.144 0.536 0.2709 0.915 0.691 1.21 -0.644 0.415 0.121 0.9184 0.525 0.233 1.18 -0.778 0.447 0.0818 1.087 0.459 0.191 1.1 -0.342 0.387 0.378 0.4229 0.711 0.332 1.52 PRS_PLINK_0.00398107170553497 FALSE 588.2 Secondary hyperparathyroidism (of renal origin) Both 141 833 11 genitourinary black 833, 141 208, 30 208, 34 208, 45 208, 32 0.106 0.098 0.277 0.5574 1.11 0.918 1.35 0.179 0.272 0.511 0.2912 1.2 0.701 2.04 0.442 0.265 0.0954 1.021 1.56 0.926 2.61 0.137 0.281 0.628 0.2024 1.15 0.66 1.99 PRS_PLINK_0.00398107170553497 FALSE 589 Abnormal results of function study of kidney Both 176 1020 11 genitourinary black 1020, 176 255, 47 255, 40 255, 40 255, 49 0.0628 0.0835 0.452 0.345 1.06 0.904 1.25 -0.13 0.235 0.581 0.2357 0.878 0.554 1.39 -0.19 0.242 0.431 0.3657 0.827 0.515 1.33 0.166 0.239 0.487 0.3126 1.18 0.739 1.88 PRS_PLINK_0.00398107170553497 FALSE 590 Pyelonephritis Both 244 1454 11 genitourinary black 1454, 244 364, 53 363, 57 363, 68 364, 66 0.113 0.0706 0.111 0.9559 1.12 0.975 1.29 0.12 0.205 0.56 0.2519 1.13 0.754 1.69 0.309 0.202 0.126 0.9011 1.36 0.917 2.02 0.363 0.208 0.0811 1.091 1.44 0.956 2.16 PRS_PLINK_0.00398107170553497 FALSE 591 Urinary tract infection Both 1876 2906 11 genitourinary black 2906, 1876 727, 489 726, 454 726, 462 727, 470 0.025 0.0312 0.424 0.3728 1.03 0.964 1.09 -0.0498 0.0874 0.569 0.2448 0.951 0.802 1.13 0.0237 0.0878 0.787 0.104 1.02 0.862 1.22 0.108 0.0896 0.23 0.6391 1.11 0.934 1.33 PRS_PLINK_0.00398107170553497 FALSE 592 Cystitis and urethritis Both 611 2502 11 genitourinary black 2502, 611 626, 148 625, 151 625, 143 626, 169 0.0607 0.0466 0.193 0.715 1.06 0.97 1.16 0.00703 0.132 0.957 0.01891 1.01 0.778 1.3 -0.0419 0.133 0.754 0.1227 0.959 0.738 1.25 0.209 0.133 0.115 0.9407 1.23 0.951 1.6 PRS_PLINK_0.00398107170553497 FALSE 592.1 Cystitis Both 596 2451 11 genitourinary black 2451, 596 613, 144 613, 146 612, 141 613, 165 0.0502 0.0473 0.288 0.5409 1.05 0.958 1.15 -0.0201 0.133 0.88 0.05531 0.98 0.755 1.27 -0.0397 0.135 0.768 0.1144 0.961 0.738 1.25 0.193 0.134 0.149 0.8277 1.21 0.933 1.58 PRS_PLINK_0.00398107170553497 FALSE 592.11 Acute cystitis Both 409 1924 11 genitourinary black 1924, 409 481, 105 481, 91 481, 101 481, 112 0.0164 0.0562 0.77 0.1134 1.02 0.91 1.14 -0.156 0.16 0.329 0.4826 0.856 0.625 1.17 -0.0742 0.156 0.635 0.1972 0.928 0.684 1.26 0.126 0.156 0.418 0.3783 1.13 0.835 1.54 PRS_PLINK_0.00398107170553497 FALSE 592.12 Chronic cystitis Both 48 317 11 genitourinary black 317, 48 80, 12 79, 15 79, 14 79, 7 -0.0478 0.146 0.743 0.1287 0.953 0.716 1.27 0.2 0.411 0.626 0.2032 1.22 0.546 2.73 0.153 0.422 0.716 0.1449 1.17 0.51 2.66 -0.225 0.49 0.647 0.1891 0.799 0.306 2.09 PRS_PLINK_0.00398107170553497 TRUE 592.13 Chronic interstitial cystitis Both 69 543 11 genitourinary black 543, 69 136, 14 136, 16 135, 20 136, 19 0.089 0.129 0.492 0.3083 1.09 0.848 1.41 -0.0367 0.378 0.923 0.03492 0.964 0.459 2.02 0.434 0.37 0.241 0.6175 1.54 0.747 3.19 0.212 0.366 0.562 0.2501 1.24 0.604 2.53 PRS_PLINK_0.00398107170553497 FALSE 592.2 Urethritis and urethral syndrome Both 30 204 11 genitourinary black 204, 30 51, 6 51, 8 51, 6 51, 10 0.33 0.2 0.1 0.9988 1.39 0.939 2.06 0.0454 0.544 0.934 0.02984 1.05 0.36 3.04 0.0746 0.578 0.897 0.04709 1.08 0.347 3.34 0.462 0.543 0.395 0.4036 1.59 0.547 4.61 PRS_PLINK_0.00398107170553497 TRUE 593 Hematuria Both 797 2863 11 genitourinary black 2863, 797 716, 197 716, 209 715, 193 716, 198 0.0165 0.0417 0.693 0.1592 1.02 0.937 1.1 0.0525 0.116 0.65 0.187 1.05 0.84 1.32 -0.00176 0.119 0.988 0.005178 0.998 0.791 1.26 0.0798 0.121 0.509 0.2929 1.08 0.854 1.37 PRS_PLINK_0.00398107170553497 FALSE 593.1 Gross hematuria Both 189 1194 11 genitourinary black 1194, 189 299, 41 298, 53 298, 45 299, 50 0.011 0.0836 0.895 0.04796 1.01 0.858 1.19 0.315 0.228 0.167 0.776 1.37 0.876 2.14 0.0996 0.235 0.671 0.1731 1.1 0.697 1.75 0.309 0.238 0.193 0.7141 1.36 0.855 2.17 PRS_PLINK_0.00398107170553497 FALSE 593.2 Microscopic hematuria Both 230 1097 11 genitourinary black 1097, 230 275, 60 274, 58 274, 59 274, 53 -0.0133 0.0763 0.861 0.06483 0.987 0.85 1.15 0.0155 0.206 0.94 0.02686 1.02 0.679 1.52 0.0201 0.207 0.923 0.03483 1.02 0.68 1.53 0.0287 0.219 0.895 0.04796 1.03 0.671 1.58 PRS_PLINK_0.00398107170553497 FALSE 594 Urinary calculus Both 638 4353 11 genitourinary black 4353, 638 1088, 129 1088, 150 1088, 167 1088, 192 0.099 0.0436 0.0232 1.634 1.1 1.01 1.2 0.141 0.128 0.273 0.5642 1.15 0.895 1.48 0.278 0.127 0.0288 1.541 1.32 1.03 1.7 0.365 0.125 0.00352 2.454 1.44 1.13 1.84 PRS_PLINK_0.00398107170553497 FALSE 594.1 Calculus of kidney Both 594 4327 11 genitourinary black 4327, 594 1081, 122 1082, 140 1081, 153 1082, 179 0.0973 0.045 0.0304 1.517 1.1 1.01 1.2 0.122 0.132 0.354 0.4507 1.13 0.873 1.46 0.244 0.131 0.0625 1.204 1.28 0.987 1.65 0.34 0.129 0.00818 2.087 1.4 1.09 1.81 PRS_PLINK_0.00398107170553497 FALSE 594.2 Calculus of lower urinary tract Both 28 286 11 genitourinary black 286, 28 72, 4 71, 8 71, 10 72, 6 0.203 0.199 0.308 0.5121 1.23 0.83 1.81 0.732 0.624 0.241 0.6185 2.08 0.612 7.06 1.16 0.61 0.0581 1.236 3.18 0.961 10.5 0.634 0.638 0.321 0.4937 1.88 0.539 6.59 PRS_PLINK_0.00398107170553497 TRUE 594.3 Calculus of ureter Both 142 1383 11 genitourinary black 1383, 142 346, 26 346, 32 345, 42 346, 42 0.092 0.0913 0.313 0.5038 1.1 0.917 1.31 0.234 0.271 0.387 0.4123 1.26 0.743 2.15 0.529 0.261 0.0425 1.372 1.7 1.02 2.83 0.533 0.266 0.0454 1.343 1.7 1.01 2.87 PRS_PLINK_0.00398107170553497 FALSE 594.8 Renal colic Both 51 421 11 genitourinary black 421, 51 106, 10 105, 13 105, 14 105, 14 0.1 0.155 0.519 0.285 1.11 0.816 1.5 0.266 0.426 0.533 0.2735 1.3 0.566 3 0.588 0.423 0.165 0.7829 1.8 0.785 4.13 0.524 0.436 0.23 0.6391 1.69 0.719 3.97 PRS_PLINK_0.00398107170553497 FALSE 595 Hydronephrosis Both 164 1737 11 genitourinary black 1737, 164 434, 28 434, 42 434, 47 434, 47 0.0987 0.083 0.234 0.6309 1.1 0.938 1.3 0.413 0.249 0.0974 1.011 1.51 0.927 2.46 0.547 0.248 0.0276 1.56 1.73 1.06 2.81 0.616 0.252 0.0144 1.841 1.85 1.13 3.03 PRS_PLINK_0.00398107170553497 FALSE 596 Other disorders of bladder Both 416 3124 11 genitourinary black 3124, 416 780, 88 781, 100 781, 101 781, 127 0.11 0.0536 0.0404 1.394 1.12 1 1.24 0.0996 0.155 0.52 0.2843 1.1 0.816 1.5 0.103 0.156 0.509 0.293 1.11 0.816 1.51 0.366 0.151 0.0156 1.808 1.44 1.07 1.94 PRS_PLINK_0.00398107170553497 FALSE 596.1 Bladder neck obstruction Both 28 284 11 genitourinary black 284, 28 71, 2 71, 6 71, 7 71, 13 0.431 0.205 0.0356 1.448 1.54 1.03 2.3 0.621 0.681 0.362 0.4411 1.86 0.49 7.07 0.668 0.679 0.325 0.4883 1.95 0.516 7.38 2.03 0.786 0.00996 2.002 7.59 1.62 35.4 PRS_PLINK_0.00398107170553497 TRUE 596.5 Functional disorders of bladder Both 273 2090 11 genitourinary black 2090, 273 522, 62 522, 62 522, 66 523, 83 0.104 0.066 0.114 0.9431 1.11 0.975 1.26 -0.00272 0.19 0.989 0.005 0.997 0.688 1.45 0.0933 0.189 0.622 0.2061 1.1 0.758 1.59 0.318 0.183 0.0812 1.091 1.37 0.961 1.97 PRS_PLINK_0.00398107170553497 FALSE 597 Other disorders of urethra and urinary tract Both 106 1139 11 genitourinary black 1139, 106 285, 33 285, 25 284, 21 285, 27 -0.0522 0.103 0.614 0.212 0.949 0.775 1.16 -0.307 0.276 0.266 0.5756 0.735 0.428 1.26 -0.536 0.291 0.0653 1.185 0.585 0.331 1.03 -0.248 0.279 0.374 0.4268 0.78 0.451 1.35 PRS_PLINK_0.00398107170553497 FALSE 597.1 Urethral stricture (not specified as infectious) Both 28 425 11 genitourinary black 425, 28 107, 11 106, 5 106, 7 106, 5 -0.182 0.19 0.339 0.4696 0.834 0.574 1.21 -0.526 0.536 0.327 0.4851 0.591 0.207 1.69 -0.327 0.481 0.497 0.3037 0.721 0.281 1.85 -0.667 0.54 0.217 0.663 0.513 0.178 1.48 PRS_PLINK_0.00398107170553497 TRUE 597.2 Urinary complications NEC Both 99 1005 11 genitourinary black 1005, 99 252, 29 251, 23 251, 24 251, 23 -0.118 0.114 0.3 0.5231 0.889 0.711 1.11 -0.167 0.296 0.571 0.243 0.846 0.474 1.51 -0.0993 0.3 0.74 0.1306 0.905 0.503 1.63 -0.185 0.306 0.545 0.2636 0.831 0.457 1.51 PRS_PLINK_0.00398107170553497 FALSE 597.8 Urethral hypermobility/ISD Both 24 280 11 genitourinary black 280, 24 70, 7 70, 5 70, 3 70, 9 0.154 0.211 0.466 0.3319 1.17 0.771 1.76 -0.57 0.582 0.328 0.4846 0.566 0.181 1.77 -1.04 0.648 0.108 0.9675 0.353 0.0992 1.26 -0.166 0.564 0.769 0.114 0.847 0.281 2.56 PRS_PLINK_0.00398107170553497 TRUE 598 Abnormal findings on examination of urine Both 24 162 11 genitourinary black 162, 24 41, 3 40, 11 40, 3 41, 7 0.297 0.236 0.209 0.6808 1.35 0.847 2.14 1.23 0.629 0.0506 1.296 3.42 0.997 11.8 0.129 0.745 0.863 0.06414 1.14 0.264 4.9 0.832 0.671 0.215 0.6676 2.3 0.617 8.56 PRS_PLINK_0.00398107170553497 TRUE 598.4 Other cells and casts in urine Both 23 143 11 genitourinary black 143, 23 36, 3 36, 8 35, 5 36, 7 0.315 0.239 0.188 0.7266 1.37 0.858 2.19 0.961 0.671 0.152 0.8181 2.61 0.702 9.74 0.888 0.778 0.254 0.595 2.43 0.528 11.2 0.918 0.697 0.188 0.7268 2.5 0.639 9.81 PRS_PLINK_0.00398107170553497 TRUE 599 Other symptoms/disorders or the urinary system Both 2320 2768 11 genitourinary black 2768, 2320 691, 557 692, 614 692, 559 692, 590 0.0245 0.0297 0.408 0.3888 1.02 0.967 1.09 0.0863 0.0827 0.297 0.5276 1.09 0.927 1.28 -0.0132 0.0845 0.876 0.05731 0.987 0.836 1.16 0.0935 0.0854 0.274 0.5625 1.1 0.929 1.3 PRS_PLINK_0.00398107170553497 FALSE 599.1 Urinary obstruction Both 67 414 11 genitourinary black 414, 67 104, 13 103, 14 103, 22 104, 18 0.0626 0.139 0.653 0.1853 1.06 0.811 1.4 0.189 0.423 0.655 0.1834 1.21 0.527 2.77 0.587 0.384 0.126 0.8983 1.8 0.847 3.82 0.216 0.399 0.588 0.2303 1.24 0.568 2.71 PRS_PLINK_0.00398107170553497 FALSE 599.2 Retention of urine Both 588 2434 11 genitourinary black 2434, 588 608, 131 608, 149 608, 147 609, 161 0.0525 0.048 0.274 0.5626 1.05 0.959 1.16 0.1 0.136 0.462 0.3349 1.11 0.846 1.44 0.0507 0.138 0.713 0.1471 1.05 0.803 1.38 0.178 0.139 0.201 0.696 1.19 0.909 1.57 PRS_PLINK_0.00398107170553497 FALSE 599.3 Dysuria Both 962 2631 11 genitourinary black 2631, 962 657, 232 658, 252 657, 225 658, 253 0.0467 0.039 0.232 0.6353 1.05 0.971 1.13 0.0869 0.109 0.424 0.3722 1.09 0.881 1.35 -0.0225 0.112 0.84 0.07558 0.978 0.785 1.22 0.107 0.112 0.34 0.4687 1.11 0.894 1.39 PRS_PLINK_0.00398107170553497 FALSE 599.4 Urinary incontinence Both 915 2567 11 genitourinary black 2567, 915 641, 225 642, 242 641, 203 642, 245 0.0192 0.0408 0.638 0.1952 1.02 0.941 1.1 0.022 0.115 0.848 0.07168 1.02 0.816 1.28 -0.148 0.118 0.211 0.6755 0.862 0.684 1.09 0.121 0.118 0.305 0.5161 1.13 0.896 1.42 PRS_PLINK_0.00398107170553497 FALSE 599.5 Frequency of urination and polyuria Both 1008 2701 11 genitourinary black 2701, 1008 675, 231 675, 263 675, 238 675, 276 0.0403 0.0387 0.298 0.5256 1.04 0.965 1.12 0.0838 0.109 0.442 0.3547 1.09 0.878 1.35 -0.00488 0.111 0.965 0.01546 0.995 0.8 1.24 0.187 0.111 0.0916 1.038 1.21 0.97 1.5 PRS_PLINK_0.00398107170553497 FALSE 599.6 Oliguria and anuria Both 83 458 11 genitourinary black 458, 83 115, 17 114, 20 114, 21 115, 25 0.148 0.125 0.237 0.6253 1.16 0.907 1.48 0.214 0.357 0.55 0.26 1.24 0.615 2.49 0.28 0.369 0.449 0.348 1.32 0.641 2.73 0.513 0.352 0.146 0.8369 1.67 0.837 3.33 PRS_PLINK_0.00398107170553497 FALSE 599.7 Urethral discharge Both 13 71 11 genitourinary black 71, 13 18, 2 18, 3 17, 5 18, 3 0.139 0.305 0.649 0.1876 1.15 0.631 2.09 1.13 1.36 0.406 0.3919 3.09 0.216 44.2 0.434 0.935 0.643 0.1919 1.54 0.247 9.64 0.255 0.96 0.791 0.102 1.29 0.197 8.47 PRS_PLINK_0.00398107170553497 TRUE 599.8 Other symptoms involving urinary system Both 824 2612 11 genitourinary black 2612, 824 652, 200 653, 208 653, 191 653, 225 0.0232 0.042 0.581 0.2356 1.02 0.943 1.11 0.013 0.117 0.912 0.04 1.01 0.805 1.28 -0.0979 0.12 0.416 0.3813 0.907 0.716 1.15 0.117 0.119 0.327 0.4852 1.12 0.89 1.42 PRS_PLINK_0.00398107170553497 FALSE 599.9 Other abnormality of urination Both 559 2440 11 genitourinary black 2440, 559 609, 124 610, 139 610, 151 610, 145 0.0259 0.0492 0.598 0.2234 1.03 0.932 1.13 0.0907 0.139 0.513 0.2895 1.09 0.834 1.44 0.133 0.138 0.336 0.4733 1.14 0.871 1.5 0.154 0.143 0.282 0.5504 1.17 0.881 1.54 PRS_PLINK_0.00398107170553497 FALSE 600 Hyperplasia of prostate Male 341 521 11 genitourinary black 521, 341 131, 65 130, 76 130, 106 130, 94 0.119 0.0816 0.144 0.8423 1.13 0.96 1.32 0.0717 0.233 0.758 0.1203 1.07 0.681 1.7 0.457 0.234 0.051 1.293 1.58 0.998 2.5 0.264 0.229 0.248 0.6048 1.3 0.832 2.04 PRS_PLINK_0.00398107170553497 FALSE 601 Inflammatory diseases of prostate Male 81 455 11 genitourinary black 455, 81 114, 13 114, 22 113, 22 114, 24 0.225 0.135 0.0953 1.021 1.25 0.961 1.63 0.519 0.386 0.178 0.7488 1.68 0.789 3.58 0.788 0.395 0.0464 1.334 2.2 1.01 4.77 0.774 0.383 0.0435 1.362 2.17 1.02 4.6 PRS_PLINK_0.00398107170553497 FALSE 601.1 Prostatitis Male 45 223 11 genitourinary black 223, 45 56, 5 56, 10 55, 18 56, 12 0.294 0.181 0.105 0.9771 1.34 0.94 1.91 0.597 0.591 0.312 0.5059 1.82 0.571 5.79 1.24 0.571 0.0304 1.517 3.44 1.12 10.6 0.913 0.569 0.109 0.9642 2.49 0.817 7.6 PRS_PLINK_0.00398107170553497 TRUE 601.11 Acute prostatitis Male 10 62 11 genitourinary black 62, 10 16, 2 15, 4 15, 1 16, 3 -0.105 0.335 0.753 0.123 0.9 0.467 1.73 0.559 0.869 0.52 0.2841 1.75 0.319 9.59 -1.25 1.33 0.347 0.4592 0.286 0.021 3.9 0.36 0.854 0.673 0.1717 1.43 0.269 7.64 PRS_PLINK_0.00398107170553497 TRUE 601.12 Chronic prostatitis Male 8 46 11 genitourinary black 46, 8 12, 2 11, 2 11, 3 12, 1 -0.0898 0.414 0.828 0.08183 0.914 0.406 2.06 -0.363 1.32 0.783 0.1064 0.695 0.0526 9.19 -0.438 1.38 0.75 0.1249 0.645 0.0435 9.56 1.41 1.7 0.408 0.3893 4.08 0.146 114 PRS_PLINK_0.00398107170553497 TRUE 601.3 Orchitis and epididymitis Male 29 172 11 genitourinary black 172, 29 43, 6 43, 11 43, 6 43, 6 0.0179 0.218 0.935 0.02938 1.02 0.664 1.56 0.439 0.545 0.421 0.3761 1.55 0.533 4.51 0.0525 0.61 0.932 0.03081 1.05 0.319 3.49 0.189 0.6 0.753 0.1232 1.21 0.372 3.92 PRS_PLINK_0.00398107170553497 TRUE 601.4 Balanoposthitis Male 7 60 11 genitourinary black 60, 7 15, 0 15, 2 15, 3 15, 2 0.149 0.378 0.693 0.1593 1.16 0.554 2.43 0.232 1.42 0.87 0.06056 1.26 0.0786 20.2 2 1.46 0.168 0.7735 7.42 0.428 129 1.2 1.36 0.377 0.4232 3.33 0.231 47.9 PRS_PLINK_0.00398107170553497 TRUE 601.8 Other inflammatory disorders of male genital organs Male 10 75 11 genitourinary black 75, 10 19, 3 19, 1 18, 3 19, 3 -0.032 0.334 0.924 0.0345 0.968 0.503 1.86 -0.85 0.926 0.359 0.4452 0.427 0.0695 2.63 0.158 0.905 0.861 0.06487 1.17 0.199 6.91 -0.297 0.928 0.749 0.1257 0.743 0.12 4.58 PRS_PLINK_0.00398107170553497 TRUE 602 Other disorders of prostate Male 31 166 11 genitourinary black 166, 31 42, 6 41, 9 41, 5 42, 11 0.0772 0.203 0.703 0.1531 1.08 0.726 1.61 0.353 0.579 0.542 0.2661 1.42 0.458 4.43 -0.303 0.632 0.632 0.1994 0.739 0.214 2.55 0.52 0.562 0.355 0.4495 1.68 0.559 5.06 PRS_PLINK_0.00398107170553497 TRUE 602.3 Dysplasia of prostate Male 11 41 11 genitourinary black 41, 11 11, 3 10, 2 10, 2 10, 4 0.28 0.408 0.493 0.3067 1.32 0.594 2.94 -0.0941 1.09 0.931 0.03103 0.91 0.108 7.67 -0.577 1.12 0.605 0.2182 0.562 0.0631 5 -0.139 1.07 0.896 0.04767 0.87 0.107 7.04 PRS_PLINK_0.00398107170553497 TRUE 603 Other disorders of testis Male 28 172 11 genitourinary black 172, 28 43, 9 43, 5 43, 5 43, 9 -0.075 0.215 0.727 0.1383 0.928 0.609 1.41 -0.576 0.583 0.323 0.4902 0.562 0.179 1.76 -0.785 0.592 0.185 0.7333 0.456 0.143 1.46 -0.0948 0.527 0.857 0.06692 0.91 0.324 2.56 PRS_PLINK_0.00398107170553497 TRUE 603.1 Hydrocele Male 16 126 11 genitourinary black 126, 16 32, 4 31, 4 31, 2 32, 6 -0.0568 0.255 0.823 0.08446 0.945 0.574 1.56 -0.357 0.737 0.629 0.2017 0.7 0.165 2.97 -0.54 0.812 0.506 0.2956 0.583 0.119 2.86 0.00559 0.681 0.993 0.002855 1.01 0.265 3.82 PRS_PLINK_0.00398107170553497 TRUE 603.2 Spermatocele Male 18 58 11 genitourinary black 58, 18 15, 4 14, 3 14, 6 15, 5 0.0462 0.297 0.877 0.05724 1.05 0.585 1.88 -0.202 0.875 0.817 0.08773 0.817 0.147 4.54 0.356 0.789 0.652 0.1861 1.43 0.304 6.7 0.0545 0.842 0.948 0.02302 1.06 0.203 5.5 PRS_PLINK_0.00398107170553497 TRUE 604 Disorders of penis Male 41 257 11 genitourinary black 257, 41 65, 4 64, 14 64, 11 64, 12 0.341 0.179 0.0564 1.248 1.41 0.991 2 1.21 0.559 0.0301 1.521 3.36 1.12 10 1.04 0.577 0.0728 1.138 2.82 0.909 8.73 0.963 0.585 0.0994 1.003 2.62 0.833 8.24 PRS_PLINK_0.00398107170553497 TRUE 604.1 Redundant prepuce and phimosis/BXO Male 7 67 11 genitourinary black 67, 7 17, 2 17, 1 16, 2 17, 2 -0.2 0.402 0.619 0.2086 0.818 0.372 1.8 2.08 2.02 0.305 0.5159 7.98 0.151 422 0.186 1.06 0.861 0.06503 1.2 0.151 9.59 0.164 1.06 0.877 0.05718 1.18 0.148 9.37 PRS_PLINK_0.00398107170553497 TRUE 604.3 Peyronie's disease Male 11 79 11 genitourinary black 79, 11 20, 1 20, 4 19, 4 20, 2 0.257 0.327 0.433 0.364 1.29 0.681 2.46 3.52 1.95 0.0705 1.152 33.8 0.745 1530 0.99 0.978 0.311 0.5069 2.69 0.396 18.3 0.677 1.02 0.508 0.2942 1.97 0.265 14.6 PRS_PLINK_0.00398107170553497 TRUE 605 Erectile dysfunction [ED] Male 285 505 11 genitourinary black 505, 285 127, 56 126, 76 126, 77 126, 76 0.0816 0.0831 0.326 0.4864 1.08 0.922 1.28 0.406 0.234 0.0829 1.081 1.5 0.949 2.37 0.408 0.238 0.0862 1.065 1.5 0.944 2.4 0.403 0.238 0.0896 1.048 1.5 0.94 2.38 PRS_PLINK_0.00398107170553497 FALSE 608 Other disorders of male genital organs Male 150 540 11 genitourinary black 540, 150 135, 27 135, 39 135, 38 135, 46 0.159 0.098 0.104 0.9824 1.17 0.968 1.42 0.308 0.29 0.288 0.5399 1.36 0.77 2.4 0.366 0.288 0.204 0.69 1.44 0.82 2.54 0.526 0.28 0.0608 1.216 1.69 0.977 2.93 PRS_PLINK_0.00398107170553497 FALSE 609 Male infertility and abnormal spermatozoa Male 34 224 11 genitourinary black 224, 34 56, 6 56, 8 56, 10 56, 10 0.0558 0.203 0.783 0.1061 1.06 0.711 1.57 0.0428 0.568 0.94 0.02691 1.04 0.343 3.17 0.505 0.551 0.359 0.4448 1.66 0.563 4.88 0.448 0.548 0.414 0.3829 1.56 0.534 4.58 PRS_PLINK_0.00398107170553497 TRUE 609.1 Infertility, male Male 22 152 11 genitourinary black 152, 22 38, 4 38, 5 38, 5 38, 8 0.114 0.252 0.651 0.1862 1.12 0.684 1.84 -0.0726 0.715 0.919 0.03664 0.93 0.229 3.78 0.44 0.737 0.551 0.2592 1.55 0.366 6.58 0.688 0.695 0.322 0.4926 1.99 0.51 7.77 PRS_PLINK_0.00398107170553497 TRUE 609.11 Azoospermia and oligospermia Male 6 49 11 genitourinary black 49, 6 13, 1 12, 1 12, 2 12, 2 0.185 0.546 0.735 0.1335 1.2 0.412 3.51 -0.587 1.44 0.684 0.1647 0.556 0.0328 9.43 -1.36 1.52 0.371 0.4303 0.257 0.013 5.06 0.78 1.44 0.589 0.2301 2.18 0.129 36.8 PRS_PLINK_0.00398107170553497 TRUE 609.2 Abnormal spermatozoa Male 12 65 11 genitourinary black 65, 12 17, 4 16, 2 16, 5 16, 1 -0.236 0.371 0.525 0.2795 0.79 0.382 1.64 0.0188 0.9 0.983 0.00729 1.02 0.175 5.94 -0.273 0.903 0.763 0.1176 0.761 0.13 4.47 -1.45 1.26 0.253 0.5971 0.235 0.0197 2.81 PRS_PLINK_0.00398107170553497 TRUE 610 Benign mammary dysplasias Female 1038 1709 11 genitourinary black 1709, 1038 428, 231 427, 246 427, 276 427, 285 0.0481 0.0417 0.249 0.6039 1.05 0.967 1.14 0.0279 0.118 0.813 0.08985 1.03 0.816 1.3 0.125 0.117 0.287 0.5418 1.13 0.9 1.43 0.147 0.119 0.214 0.6689 1.16 0.918 1.46 PRS_PLINK_0.00398107170553497 FALSE 610.1 Cystic mastopathy Female 450 1500 11 genitourinary black 1500, 450 375, 104 375, 110 375, 114 375, 122 -0.00513 0.0559 0.927 0.03298 0.995 0.892 1.11 9.74e-06 0.157 1 2.147e-05 1 0.735 1.36 0.0158 0.157 0.92 0.03622 1.02 0.746 1.38 0.0513 0.159 0.747 0.1267 1.05 0.771 1.44 PRS_PLINK_0.00398107170553497 FALSE 610.2 Fibroadenosis of breast Female 13 50 11 genitourinary black 50, 13 13, 3 12, 2 12, 1 13, 7 0.378 0.347 0.276 0.5591 1.46 0.739 2.88 -0.275 0.996 0.783 0.1064 0.76 0.108 5.35 -0.206 1.07 0.848 0.07168 0.814 0.0996 6.66 0.917 0.879 0.297 0.5279 2.5 0.447 14 PRS_PLINK_0.00398107170553497 TRUE 610.4 Benign neoplasm of breast Female 824 1697 11 genitourinary black 1697, 824 425, 182 424, 190 424, 218 424, 234 0.0653 0.045 0.147 0.8336 1.07 0.977 1.17 0.00676 0.128 0.958 0.01865 1.01 0.783 1.29 0.133 0.128 0.298 0.5251 1.14 0.889 1.47 0.181 0.128 0.157 0.8038 1.2 0.933 1.54 PRS_PLINK_0.00398107170553497 FALSE 610.8 Other specified benign mammary dysplasias Female 312 1284 11 genitourinary black 1284, 312 321, 64 321, 87 321, 74 321, 87 0.0276 0.0649 0.671 0.1735 1.03 0.905 1.17 0.28 0.185 0.131 0.8843 1.32 0.92 1.9 0.0955 0.19 0.616 0.2108 1.1 0.758 1.6 0.228 0.189 0.228 0.6412 1.26 0.867 1.82 PRS_PLINK_0.00398107170553497 FALSE 611 Abnormal findings on mammogram or breast exam Both 1957 1869 11 genitourinary black 1869, 1957 468, 436 467, 451 467, 523 467, 546 0.0926 0.0347 0.00762 2.118 1.1 1.02 1.17 0.0178 0.0981 0.856 0.0675 1.02 0.84 1.23 0.165 0.0977 0.0923 1.035 1.18 0.973 1.43 0.245 0.0984 0.0127 1.898 1.28 1.05 1.55 PRS_PLINK_0.00398107170553497 FALSE 611.1 Abnormal mammogram Both 1691 1699 11 genitourinary black 1699, 1691 425, 360 425, 396 424, 449 425, 485 0.0962 0.0366 0.0086 2.066 1.1 1.02 1.18 0.182 0.104 0.0795 1.1 1.2 0.979 1.47 PRS_PLINK_0.00398107170553497 FALSE 611.11 Mammographic microcalcification Both 424 1145 11 genitourinary black 1145, 424 287, 101 286, 86 286, 128 286, 109 0.0617 0.0599 0.303 0.5183 1.06 0.946 1.2 -0.176 0.172 0.306 0.5139 0.839 0.598 1.17 0.236 0.163 0.148 0.8303 1.27 0.92 1.74 0.06 0.172 0.727 0.1387 1.06 0.759 1.49 PRS_PLINK_0.00398107170553497 FALSE 611.3 Lump or mass in breast Both 1070 1863 11 genitourinary black 1863, 1070 466, 246 466, 229 465, 290 466, 305 0.0927 0.0404 0.0217 1.663 1.1 1.01 1.19 -0.0749 0.117 0.521 0.2833 0.928 0.738 1.17 0.136 0.114 0.231 0.637 1.15 0.917 1.43 0.18 0.115 0.116 0.9362 1.2 0.957 1.5 PRS_PLINK_0.00398107170553497 FALSE 612 Breast conditions, congenital or relating to hormones Both 236 983 11 genitourinary black 983, 236 246, 43 246, 53 245, 69 246, 71 0.226 0.0771 0.00342 2.466 1.25 1.08 1.46 0.172 0.228 0.452 0.3452 1.19 0.759 1.86 0.459 0.221 0.0377 1.424 1.58 1.03 2.44 0.479 0.225 0.0333 1.477 1.61 1.04 2.51 PRS_PLINK_0.00398107170553497 FALSE 612.1 Galactorrhea Both 36 168 11 genitourinary black 168, 36 42, 3 42, 11 42, 9 42, 13 0.877 0.638 0.17 0.7706 2.4 0.688 8.4 1.35 0.658 0.0406 1.391 3.85 1.06 14 PRS_PLINK_0.00398107170553497 TRUE 612.2 Hypertrophy of breast (Gynecomastia) Both 165 717 11 genitourinary black 717, 165 180, 34 179, 32 179, 50 179, 49 0.132 0.0936 0.158 0.8018 1.14 0.95 1.37 -0.223 0.28 0.426 0.3707 0.8 0.463 1.38 0.287 0.252 0.253 0.5966 1.33 0.814 2.18 0.245 0.266 0.357 0.4469 1.28 0.758 2.15 PRS_PLINK_0.00398107170553497 FALSE 612.3 Congenital anomalies of breast Both 30 101 11 genitourinary black 101, 30 26, 6 25, 6 25, 8 25, 10 0.535 0.263 0.0415 1.381 1.71 1.02 2.86 0.352 0.691 0.61 0.2146 1.42 0.367 5.51 1.41 0.835 0.0901 1.045 4.12 0.801 21.1 0.723 0.666 0.277 0.5574 2.06 0.559 7.6 PRS_PLINK_0.00398107170553497 TRUE 613 Other nonmalignant breast conditions Both 1076 3084 11 genitourinary black 3084, 1076 770, 228 771, 260 771, 312 771, 276 0.0646 0.0367 0.0786 1.105 1.07 0.993 1.15 0.0973 0.106 0.357 0.4474 1.1 0.896 1.36 0.262 0.103 0.0109 1.961 1.3 1.06 1.59 0.15 0.107 0.159 0.798 1.16 0.943 1.43 PRS_PLINK_0.00398107170553497 FALSE 613.1 Inflammatory disease of breast Both 135 861 11 genitourinary black 861, 135 215, 26 215, 32 215, 40 215, 37 PRS_PLINK_0.00398107170553497 FALSE 613.5 Mastodynia Both 524 2359 11 genitourinary black 2359, 524 589, 117 590, 115 589, 149 590, 143 0.0824 0.0495 0.096 1.018 1.09 0.985 1.2 -0.0614 0.145 0.672 0.1723 0.94 0.707 1.25 0.19 0.138 0.17 0.7705 1.21 0.922 1.59 0.164 0.142 0.247 0.6069 1.18 0.892 1.56 PRS_PLINK_0.00398107170553497 FALSE 613.7 Other signs and symptoms in breast Both 255 1368 11 genitourinary black 1368, 255 342, 52 342, 55 342, 74 342, 74 0.141 0.0695 0.0422 1.375 1.15 1.01 1.32 0.0432 0.209 0.836 0.07763 1.04 0.693 1.57 0.328 0.198 0.0986 1.006 1.39 0.941 2.05 0.333 0.204 0.103 0.987 1.39 0.935 2.08 PRS_PLINK_0.00398107170553497 FALSE 613.8 Other specified disorders of breast Both 245 1371 11 genitourinary black 1371, 245 342, 40 343, 56 342, 81 343, 68 PRS_PLINK_0.00398107170553497 FALSE 613.9 Breast disorder NOS Both 402 2182 11 genitourinary black 2182, 402 546, 84 545, 100 545, 121 546, 97 0.0375 0.0563 0.506 0.2957 1.04 0.93 1.16 0.113 0.166 0.497 0.3034 1.12 0.808 1.55 PRS_PLINK_0.00398107170553497 FALSE 614 Inflammatory diseases of female pelvic organs Female 1039 2855 11 genitourinary black 2855, 1039 713, 256 714, 263 713, 260 714, 260 0.0183 0.0374 0.624 0.2045 1.02 0.946 1.1 0.0197 0.104 0.85 0.07068 1.02 0.832 1.25 0.00908 0.106 0.932 0.03074 1.01 0.82 1.24 0.0159 0.107 0.882 0.05473 1.02 0.824 1.25 PRS_PLINK_0.00398107170553497 FALSE 614.1 Pelvic peritoneal adhesions, female (postoperative) (postinfection) Female 64 432 11 genitourinary black 432, 64 107, 20 108, 14 108, 17 108, 13 -0.084 0.131 0.521 0.2831 0.919 0.711 1.19 -0.444 0.377 0.239 0.6222 0.641 0.306 1.34 -0.148 0.359 0.681 0.1672 0.863 0.427 1.74 -0.359 0.389 0.356 0.4488 0.699 0.326 1.5 PRS_PLINK_0.00398107170553497 FALSE 614.3 Pelvic inflammatory disease (PID) Female 106 610 11 genitourinary black 610, 106 153, 29 152, 26 152, 33 153, 18 -0.114 0.103 0.266 0.5743 0.892 0.73 1.09 -0.0566 0.292 0.846 0.07242 0.945 0.533 1.68 0.0679 0.279 0.808 0.0928 1.07 0.62 1.85 -0.466 0.321 0.147 0.8324 0.628 0.334 1.18 PRS_PLINK_0.00398107170553497 FALSE 614.31 Acute inflammatory pelvic disease Female 18 120 11 genitourinary black 120, 18 30, 8 30, 6 30, 2 30, 2 -0.395 0.241 0.101 0.9966 0.673 0.42 1.08 -0.341 0.615 0.579 0.2374 0.711 0.213 2.37 -0.887 0.753 0.238 0.6225 0.412 0.0942 1.8 -1.31 0.747 0.0788 1.103 0.269 0.0622 1.16 PRS_PLINK_0.00398107170553497 TRUE 614.32 Chronic inflammatory pelvic disease Female 49 233 11 genitourinary black 233, 49 59, 14 58, 7 58, 19 58, 9 -0.103 0.154 0.506 0.2955 0.902 0.667 1.22 -0.482 0.488 0.324 0.4898 0.618 0.237 1.61 0.337 0.406 0.407 0.3906 1.4 0.632 3.1 -0.369 0.47 0.433 0.3635 0.692 0.275 1.74 PRS_PLINK_0.00398107170553497 TRUE 614.33 Pelvic inflammatory disease, NOS Female 53 307 11 genitourinary black 307, 53 77, 18 77, 9 76, 14 77, 12 -0.0793 0.147 0.59 0.2294 0.924 0.692 1.23 -0.827 0.45 0.0664 1.178 0.437 0.181 1.06 -0.278 0.412 0.5 0.3006 0.757 0.338 1.7 -0.266 0.415 0.522 0.2827 0.767 0.34 1.73 PRS_PLINK_0.00398107170553497 FALSE 614.4 Inflammatory diseases of uterus, except cervix Female 37 202 11 genitourinary black 202, 37 51, 12 50, 6 50, 8 51, 11 -0.0132 0.188 0.944 0.02503 0.987 0.682 1.43 -0.557 0.517 0.281 0.5508 0.573 0.208 1.58 -0.28 0.503 0.578 0.2379 0.756 0.282 2.03 0.132 0.479 0.783 0.106 1.14 0.446 2.92 PRS_PLINK_0.00398107170553497 TRUE 614.5 Inflammatory disease of cervix, vagina, and vulva Female 942 2830 11 genitourinary black 2830, 942 707, 228 707, 246 707, 231 708, 237 0.0166 0.0387 0.668 0.1754 1.02 0.942 1.1 0.0677 0.108 0.529 0.2766 1.07 0.867 1.32 0.00193 0.11 0.986 0.006107 1 0.807 1.24 0.0318 0.111 0.774 0.1114 1.03 0.831 1.28 PRS_PLINK_0.00398107170553497 FALSE 614.51 Cervicitis and endocervicitis Female 72 371 11 genitourinary black 371, 72 93, 19 93, 23 92, 12 93, 18 -0.0794 0.123 0.519 0.2847 0.924 0.725 1.18 0.287 0.35 0.413 0.3841 1.33 0.671 2.64 -0.316 0.397 0.426 0.3704 0.729 0.335 1.59 -0.0687 0.369 0.852 0.06946 0.934 0.453 1.92 PRS_PLINK_0.00398107170553497 FALSE 614.52 Vaginitis and vulvovaginitis Female 822 2738 11 genitourinary black 2738, 822 684, 188 684, 217 684, 211 685, 206 0.0481 0.0408 0.239 0.6223 1.05 0.969 1.14 0.127 0.115 0.267 0.5736 1.14 0.907 1.42 0.0908 0.117 0.437 0.3597 1.1 0.871 1.38 0.0938 0.118 0.428 0.3687 1.1 0.871 1.38 PRS_PLINK_0.00398107170553497 FALSE 614.53 Cyst or abscess of Bartholin's gland Female 34 208 11 genitourinary black 208, 34 52, 11 52, 8 52, 8 52, 7 -0.174 0.176 0.323 0.4903 0.84 0.595 1.19 -0.219 0.511 0.668 0.175 0.803 0.295 2.19 -0.682 0.548 0.213 0.6707 0.506 0.173 1.48 -0.623 0.526 0.236 0.627 0.536 0.191 1.5 PRS_PLINK_0.00398107170553497 TRUE 614.54 Abscess or ulceration of vulva Female 56 325 11 genitourinary black 325, 56 82, 14 81, 16 81, 14 81, 12 -0.03 0.145 0.836 0.0777 0.97 0.73 1.29 0.105 0.411 0.797 0.09839 1.11 0.497 2.49 0.362 0.436 0.406 0.391 1.44 0.611 3.37 0.0546 0.443 0.902 0.04491 1.06 0.443 2.52 PRS_PLINK_0.00398107170553497 FALSE 615 Endometriosis Female 311 1990 11 genitourinary black 1990, 311 497, 82 497, 86 497, 79 498, 64 -0.0678 0.0617 0.272 0.5656 0.934 0.828 1.05 0.0553 0.168 0.741 0.13 1.06 0.761 1.47 -0.0169 0.172 0.922 0.03539 0.983 0.702 1.38 -0.203 0.182 0.265 0.5776 0.816 0.571 1.17 PRS_PLINK_0.00398107170553497 FALSE 618 Genital prolapse Female 440 3043 11 genitourinary black 3043, 440 760, 100 761, 107 760, 109 761, 124 0.108 0.0526 0.0397 1.401 1.11 1.01 1.24 0.0601 0.148 0.686 0.1638 1.06 0.794 1.42 0.07 0.15 0.64 0.1938 1.07 0.8 1.44 0.232 0.149 0.119 0.9258 1.26 0.942 1.69 PRS_PLINK_0.00398107170553497 FALSE 618.1 Prolapse of vaginal walls Female 294 2352 11 genitourinary black 2352, 294 587, 66 588, 70 588, 72 588, 86 0.143 0.0632 0.024 1.62 1.15 1.02 1.31 0.0559 0.18 0.756 0.1215 1.06 0.743 1.5 0.0748 0.183 0.682 0.1663 1.08 0.753 1.54 0.304 0.178 0.0883 1.054 1.36 0.955 1.92 PRS_PLINK_0.00398107170553497 FALSE 618.2 Uterine/Uterovaginal prolapse Female 136 960 11 genitourinary black 960, 136 240, 29 240, 31 240, 38 240, 38 0.104 0.0957 0.277 0.5572 1.11 0.92 1.34 0.0644 0.27 0.812 0.0906 1.07 0.628 1.81 0.238 0.264 0.367 0.4353 1.27 0.756 2.13 0.21 0.266 0.43 0.3666 1.23 0.732 2.08 PRS_PLINK_0.00398107170553497 FALSE 618.5 Prolapse of vaginal vault after hysterectomy Female 37 526 11 genitourinary black 526, 37 132, 5 131, 9 131, 7 132, 16 0.378 0.181 0.0368 1.434 1.46 1.02 2.08 0.648 0.528 0.22 0.6583 1.91 0.679 5.37 0.316 0.549 0.565 0.2478 1.37 0.468 4.02 1.08 0.497 0.0292 1.535 2.96 1.12 7.83 PRS_PLINK_0.00398107170553497 TRUE 618.6 Vaginal enterocele, congenital or acquired Female 82 728 11 genitourinary black 728, 82 182, 16 182, 22 182, 15 182, 29 0.179 0.126 0.154 0.8125 1.2 0.935 1.53 0.342 0.343 0.319 0.4966 1.41 0.718 2.76 -0.044 0.369 0.905 0.0433 0.957 0.464 1.97 0.577 0.342 0.0912 1.04 1.78 0.912 3.48 PRS_PLINK_0.00398107170553497 FALSE 619 Noninflammatory female genital disorders Female 1410 2663 11 genitourinary black 2663, 1410 666, 335 666, 336 665, 361 666, 377 0.0428 0.0342 0.21 0.6778 1.04 0.976 1.12 0.0011 0.0962 0.991 0.003964 1 0.829 1.21 0.0584 0.0962 0.544 0.2642 1.06 0.878 1.28 0.095 0.0968 0.326 0.4867 1.1 0.91 1.33 PRS_PLINK_0.00398107170553497 FALSE 619.1 Noninflammatory disorders of ovary, fallopian tube, and broad ligament Female 250 1543 11 genitourinary black 1543, 250 386, 63 386, 65 385, 68 386, 53 -0.0497 0.0702 0.479 0.32 0.951 0.829 1.09 0.0116 0.19 0.951 0.02168 1.01 0.697 1.47 0.0638 0.19 0.737 0.1325 1.07 0.735 1.55 -0.132 0.202 0.515 0.2886 0.876 0.589 1.3 PRS_PLINK_0.00398107170553497 FALSE 619.2 Disorders of uterus, NEC Female 162 821 11 genitourinary black 821, 162 206, 38 205, 35 205, 48 205, 41 0.0637 0.0872 0.465 0.3328 1.07 0.898 1.26 -0.064 0.256 0.802 0.0956 0.938 0.568 1.55 0.209 0.24 0.383 0.4171 1.23 0.771 1.97 0.14 0.254 0.581 0.2357 1.15 0.7 1.89 PRS_PLINK_0.00398107170553497 FALSE 619.3 Noninflammatory disorders of cervix Female 139 634 11 genitourinary black 634, 139 159, 38 158, 37 158, 27 159, 37 0.00848 0.0968 0.93 0.0314 1.01 0.834 1.22 -0.00393 0.258 0.988 0.005313 0.996 0.601 1.65 -0.403 0.282 0.153 0.816 0.668 0.385 1.16 -0.0155 0.261 0.953 0.021 0.985 0.59 1.64 PRS_PLINK_0.00398107170553497 FALSE 619.4 Noninflammatory disorders of vagina Female 672 2583 11 genitourinary black 2583, 672 646, 147 646, 159 645, 177 646, 189 0.0954 0.0449 0.0338 1.471 1.1 1.01 1.2 0.0713 0.13 0.583 0.2347 1.07 0.833 1.38 0.194 0.129 0.132 0.8809 1.21 0.944 1.56 0.24 0.129 0.0617 1.21 1.27 0.988 1.64 PRS_PLINK_0.00398107170553497 FALSE 619.5 Noninflammatory disorders of vulva and perineum Female 333 1748 11 genitourinary black 1748, 333 437, 75 437, 86 437, 85 437, 87 0.0646 0.062 0.298 0.5265 1.07 0.945 1.2 0.109 0.174 0.532 0.2744 1.11 0.793 1.57 0.0944 0.174 0.587 0.2312 1.1 0.782 1.55 0.115 0.176 0.513 0.2896 1.12 0.795 1.58 PRS_PLINK_0.00398107170553497 FALSE 620 Dysplasia of female genital organs Female 89 571 11 genitourinary black 571, 89 143, 23 143, 24 142, 21 143, 21 0.0795 0.12 0.506 0.2958 1.08 0.857 1.37 0.171 0.325 0.6 0.2218 1.19 0.627 2.24 -0.146 0.335 0.664 0.178 0.864 0.448 1.67 -0.114 0.334 0.733 0.1347 0.892 0.464 1.72 PRS_PLINK_0.00398107170553497 FALSE 620.1 Dysplasia of cervix Female 49 242 11 genitourinary black 242, 49 61, 13 60, 10 60, 14 61, 12 0.0481 0.163 0.768 0.1145 1.05 0.762 1.44 -0.0426 0.479 0.929 0.03191 0.958 0.375 2.45 0.139 0.443 0.753 0.1231 1.15 0.482 2.74 -0.376 0.478 0.431 0.3653 0.686 0.269 1.75 PRS_PLINK_0.00398107170553497 TRUE 621 Endometrial hyperplasia Female 87 635 11 genitourinary black 635, 87 159, 20 159, 20 158, 24 159, 23 0.128 0.12 0.285 0.5446 1.14 0.899 1.44 0.0635 0.339 0.852 0.06978 1.07 0.548 2.07 0.346 0.326 0.289 0.5394 1.41 0.746 2.68 0.424 0.342 0.214 0.6688 1.53 0.782 2.99 PRS_PLINK_0.00398107170553497 FALSE 622 Polyp of female genital organs Female 471 2283 11 genitourinary black 2283, 471 570, 95 571, 111 570, 135 571, 130 0.0953 0.0519 0.0662 1.179 1.1 0.994 1.22 0.153 0.153 0.316 0.5001 1.17 0.864 1.57 0.404 0.15 0.00714 2.146 1.5 1.12 2.01 0.283 0.152 0.0633 1.199 1.33 0.985 1.79 PRS_PLINK_0.00398107170553497 FALSE 622.1 Polyp of corpus uteri Female 348 1783 11 genitourinary black 1783, 348 445, 69 446, 92 445, 93 446, 94 0.0905 0.061 0.138 0.8605 1.09 0.971 1.23 0.279 0.173 0.107 0.9703 1.32 0.941 1.86 0.337 0.177 0.0569 1.245 1.4 0.99 1.98 0.28 0.179 0.117 0.9312 1.32 0.932 1.88 PRS_PLINK_0.00398107170553497 FALSE 622.2 Mucous polyp of cervix Female 172 722 11 genitourinary black 722, 172 180, 32 180, 37 180, 49 181, 54 0.192 0.0888 0.0305 1.516 1.21 1.02 1.44 0.105 0.27 0.698 0.1559 1.11 0.654 1.88 0.503 0.257 0.0502 1.299 1.65 1 2.74 0.579 0.261 0.0265 1.577 1.78 1.07 2.98 PRS_PLINK_0.00398107170553497 FALSE 623 Hypertrophy of female genital organs Female 229 1329 11 genitourinary black 1329, 229 333, 45 332, 64 332, 67 332, 53 0.0731 0.0731 0.317 0.4984 1.08 0.932 1.24 0.338 0.211 0.109 0.964 1.4 0.928 2.12 0.393 0.21 0.0608 1.216 1.48 0.982 2.23 0.156 0.222 0.484 0.3152 1.17 0.756 1.81 PRS_PLINK_0.00398107170553497 FALSE 624 Symptoms involving female genital tract Female 373 1515 11 genitourinary black 1515, 373 379, 88 379, 106 378, 85 379, 94 0.0384 0.0585 0.512 0.291 1.04 0.927 1.17 0.148 0.164 0.365 0.4374 1.16 0.841 1.6 -0.102 0.173 0.555 0.2556 0.903 0.644 1.27 0.0636 0.171 0.71 0.1488 1.07 0.762 1.49 PRS_PLINK_0.00398107170553497 FALSE 624.1 Dystrophy of female genital tract Female 53 273 11 genitourinary black 273, 53 69, 15 68, 18 68, 8 68, 12 0.061 0.155 0.695 0.1583 1.06 0.784 1.44 0.2 0.412 0.627 0.2029 1.22 0.545 2.74 -0.67 0.484 0.167 0.7784 0.512 0.198 1.32 -0.228 0.422 0.59 0.2294 0.796 0.348 1.82 PRS_PLINK_0.00398107170553497 FALSE 624.2 Atrophy of female genital tract Female 20 82 11 genitourinary black 82, 20 21, 4 20, 5 20, 5 21, 6 0.0718 0.295 0.808 0.09269 1.07 0.603 1.92 0.439 1.03 0.668 0.1752 1.55 0.208 11.6 -0.0276 0.742 0.97 0.01308 0.973 0.227 4.16 0.671 0.768 0.382 0.4181 1.96 0.435 8.81 PRS_PLINK_0.00398107170553497 TRUE 624.9 stress incontinence, female Female 452 1990 11 genitourinary black 1990, 452 497, 113 497, 127 497, 97 498, 115 0.00416 0.053 0.937 0.0281 1 0.905 1.11 0.0825 0.145 0.569 0.2449 1.09 0.818 1.44 -0.216 0.155 0.164 0.7856 0.806 0.594 1.09 -0.074 0.152 0.626 0.2037 0.929 0.69 1.25 PRS_PLINK_0.00398107170553497 FALSE 625 Pain and other symptoms associated with female genital organs Female 1556 2198 11 genitourinary black 2198, 1556 549, 405 549, 409 549, 360 550, 382 -0.0423 0.0344 0.218 0.6611 0.959 0.896 1.03 -0.0184 0.0949 0.846 0.0726 0.982 0.815 1.18 -0.159 0.0976 0.102 0.9904 0.853 0.704 1.03 -0.107 0.0986 0.278 0.5566 0.899 0.741 1.09 PRS_PLINK_0.00398107170553497 FALSE 625.1 Dyspareunia Female 323 1466 11 genitourinary black 1466, 323 366, 85 366, 93 366, 72 367, 73 -0.0723 0.0624 0.246 0.609 0.93 0.823 1.05 0.0606 0.168 0.719 0.1434 1.06 0.764 1.48 -0.218 0.181 0.227 0.6431 0.804 0.565 1.15 -0.128 0.18 0.476 0.3224 0.88 0.618 1.25 PRS_PLINK_0.00398107170553497 FALSE 626 Disorders of menstruation and other abnormal bleeding from female genital tract Female 1510 1651 11 genitourinary black 1651, 1510 413, 335 413, 392 412, 381 413, 402 0.0667 0.0379 0.0782 1.107 1.07 0.992 1.15 0.19 0.108 0.0775 1.11 1.21 0.979 1.49 0.166 0.109 0.127 0.8972 1.18 0.954 1.46 0.202 0.109 0.0636 1.197 1.22 0.989 1.51 PRS_PLINK_0.00398107170553497 FALSE 626.1 Irregular menstrual cycle/bleeding Female 1208 1519 11 genitourinary black 1519, 1208 380, 257 380, 321 379, 300 380, 330 0.0802 0.0407 0.0491 1.309 1.08 1 1.17 0.262 0.117 0.0249 1.603 1.3 1.03 1.63 0.193 0.118 0.103 0.989 1.21 0.962 1.53 0.255 0.119 0.032 1.495 1.29 1.02 1.63 PRS_PLINK_0.00398107170553497 FALSE 626.11 Absent or infrequent menstruation Female 269 829 11 genitourinary black 829, 269 208, 44 207, 69 207, 72 207, 84 0.212 0.0735 0.00398 2.4 1.24 1.07 1.43 0.462 0.219 0.0348 1.459 1.59 1.03 2.44 0.503 0.22 0.0226 1.646 1.65 1.07 2.55 0.58 0.22 0.00843 2.074 1.79 1.16 2.75 PRS_PLINK_0.00398107170553497 FALSE 626.12 Excessive or frequent menstruation Female 567 1203 11 genitourinary black 1203, 567 301, 124 301, 143 300, 141 301, 159 0.089 0.053 0.093 1.031 1.09 0.985 1.21 0.189 0.154 0.22 0.6584 1.21 0.893 1.63 0.193 0.154 0.211 0.6753 1.21 0.896 1.64 0.274 0.154 0.0744 1.129 1.32 0.973 1.78 PRS_PLINK_0.00398107170553497 FALSE 626.13 Irregular menstrual cycle Female 574 1260 11 genitourinary black 1260, 574 315, 129 315, 143 315, 137 315, 165 0.0936 0.0524 0.0738 1.132 1.1 0.991 1.22 0.15 0.151 0.318 0.4977 1.16 0.865 1.56 0.0796 0.153 0.604 0.2193 1.08 0.802 1.46 0.266 0.151 0.0777 1.11 1.3 0.971 1.75 PRS_PLINK_0.00398107170553497 FALSE 626.14 Irregular menstrual bleeding Female 265 879 11 genitourinary black 879, 265 220, 53 220, 72 219, 66 220, 74 0.106 0.0723 0.143 0.8457 1.11 0.965 1.28 0.369 0.209 0.0775 1.111 1.45 0.96 2.18 0.275 0.213 0.198 0.704 1.32 0.867 2 0.39 0.213 0.0673 1.172 1.48 0.973 2.24 PRS_PLINK_0.00398107170553497 FALSE 626.15 Infertility, female, associated with anovulation Female 120 432 11 genitourinary black 432, 120 108, 29 108, 22 108, 36 108, 33 0.0282 0.105 0.789 0.103 1.03 0.837 1.26 -0.228 0.325 0.483 0.316 0.796 0.421 1.51 0.177 0.301 0.556 0.2546 1.19 0.662 2.15 0.119 0.317 0.706 0.1511 1.13 0.606 2.1 PRS_PLINK_0.00398107170553497 FALSE 626.2 Dysmenorrhea Female 313 958 11 genitourinary black 958, 313 240, 65 239, 75 239, 89 240, 84 0.114 0.0689 0.0996 1.002 1.12 0.979 1.28 0.13 0.199 0.513 0.2901 1.14 0.771 1.68 0.271 0.194 0.162 0.7906 1.31 0.897 1.92 0.255 0.198 0.198 0.7041 1.29 0.876 1.9 PRS_PLINK_0.00398107170553497 FALSE 626.4 Premenstrual tension syndromes Female 112 365 11 genitourinary black 365, 112 92, 18 91, 34 91, 24 91, 36 0.0391 0.113 0.728 0.1377 1.04 0.834 1.3 0.491 0.339 0.148 0.8305 1.63 0.84 3.18 0.17 0.379 0.653 0.1852 1.19 0.565 2.49 0.628 0.345 0.0686 1.164 1.87 0.953 3.68 PRS_PLINK_0.00398107170553497 FALSE 626.8 Infertility, female Female 216 658 11 genitourinary black 658, 216 165, 45 164, 59 164, 48 165, 64 0.0626 0.0797 0.432 0.3644 1.06 0.911 1.24 0.235 0.234 0.314 0.5029 1.27 0.8 2 0.114 0.243 0.637 0.1959 1.12 0.697 1.8 0.264 0.238 0.266 0.575 1.3 0.818 2.08 PRS_PLINK_0.00398107170553497 FALSE 627 Menopausal and postmenopausal disorders Female 1533 1565 11 genitourinary black 1565, 1533 392, 362 391, 394 391, 394 391, 383 0.00538 0.0375 0.886 0.05264 1.01 0.934 1.08 0.0645 0.104 0.536 0.2706 1.07 0.869 1.31 0.0447 0.106 0.672 0.1727 1.05 0.85 1.29 0.0229 0.107 0.831 0.08053 1.02 0.83 1.26 PRS_PLINK_0.00398107170553497 FALSE 627.1 Postmenopausal bleeding Female 396 1186 11 genitourinary black 1186, 396 297, 83 296, 110 296, 102 297, 101 0.0164 0.0618 0.791 0.1017 1.02 0.901 1.15 0.254 0.17 0.136 0.867 1.29 0.923 1.8 0.186 0.174 0.285 0.5449 1.2 0.856 1.7 0.161 0.176 0.36 0.4441 1.17 0.832 1.66 PRS_PLINK_0.00398107170553497 FALSE 627.2 Symptomatic menopause Female 1097 1488 11 genitourinary black 1488, 1097 372, 263 372, 282 372, 274 372, 278 -0.00505 0.0416 0.903 0.04415 0.995 0.917 1.08 0.0454 0.115 0.692 0.1596 1.05 0.836 1.31 0.0205 0.117 0.861 0.06516 1.02 0.812 1.28 0.0326 0.117 0.781 0.1073 1.03 0.821 1.3 PRS_PLINK_0.00398107170553497 FALSE 627.21 Symptomatic artificial menopause Female 40 169 11 genitourinary black 169, 40 43, 8 42, 10 42, 11 42, 11 0.0603 0.184 0.743 0.1289 1.06 0.741 1.52 0.138 0.548 0.801 0.09653 1.15 0.392 3.36 0.189 0.542 0.727 0.1385 1.21 0.418 3.49 0.668 0.545 0.221 0.6563 1.95 0.67 5.68 PRS_PLINK_0.00398107170553497 TRUE 627.22 Need for Hormone replacement therapy (postmenopausal) Female 156 428 11 genitourinary black 428, 156 107, 48 107, 41 107, 46 107, 21 -0.32 0.104 0.00201 2.697 0.726 0.592 0.889 -0.212 0.264 0.422 0.375 0.809 0.482 1.36 -0.11 0.259 0.671 0.173 0.896 0.539 1.49 -0.789 0.305 0.00971 2.013 0.454 0.25 0.826 PRS_PLINK_0.00398107170553497 FALSE 627.3 Postmenopausal atrophic vaginitis Female 375 1118 11 genitourinary black 1118, 375 280, 94 279, 107 279, 82 280, 92 -0.0104 0.0629 0.869 0.06106 0.99 0.875 1.12 0.132 0.166 0.427 0.3693 1.14 0.824 1.58 -0.153 0.176 0.386 0.4138 0.858 0.608 1.21 -0.0617 0.173 0.722 0.1414 0.94 0.669 1.32 PRS_PLINK_0.00398107170553497 FALSE 627.4 Premenopausal menorrhagia Female 105 368 11 genitourinary black 368, 105 92, 21 92, 18 92, 25 92, 41 0.327 0.122 0.00751 2.124 1.39 1.09 1.76 0.00333 0.356 0.993 0.003256 1 0.499 2.02 0.37 0.347 0.286 0.543 1.45 0.733 2.86 0.891 0.335 0.00772 2.113 2.44 1.27 4.7 PRS_PLINK_0.00398107170553497 FALSE 627.5 Premature menopause and other ovarian failure Female 81 330 11 genitourinary black 330, 81 83, 22 82, 21 82, 15 83, 23 0.169 0.132 0.199 0.7001 1.18 0.915 1.53 -0.068 0.345 0.844 0.07367 0.934 0.475 1.84 -0.246 0.375 0.511 0.2912 0.782 0.374 1.63 0.0201 0.357 0.955 0.01994 1.02 0.507 2.06 PRS_PLINK_0.00398107170553497 FALSE 628 Ovarian cyst Female 487 1423 11 genitourinary black 1423, 487 356, 108 356, 117 355, 134 356, 127 0.0561 0.0543 0.302 0.5202 1.06 0.951 1.18 0.0424 0.157 0.787 0.1042 1.04 0.767 1.42 0.217 0.155 0.161 0.7944 1.24 0.917 1.68 0.119 0.158 0.452 0.3448 1.13 0.826 1.54 PRS_PLINK_0.00398107170553497 FALSE 634 Miscarriage; stillbirth Female 216 1096 12 pregnancy complications royalblue4 1096, 216 274, 60 274, 48 274, 43 274, 65 0.0378 0.0745 0.612 0.2134 1.04 0.897 1.2 -0.215 0.212 0.31 0.509 0.807 0.533 1.22 -0.333 0.22 0.13 0.8854 0.717 0.466 1.1 0.0447 0.203 0.826 0.08304 1.05 0.702 1.56 PRS_PLINK_0.00398107170553497 FALSE 634.1 Missed abortion/Hydatidiform mole Female 81 385 12 pregnancy complications royalblue4 385, 81 97, 19 96, 19 96, 17 96, 26 0.199 0.118 0.0912 1.04 1.22 0.969 1.54 0.0514 0.353 0.884 0.0535 1.05 0.527 2.1 -0.159 0.37 0.667 0.1759 0.853 0.413 1.76 0.383 0.343 0.264 0.5781 1.47 0.749 2.87 PRS_PLINK_0.00398107170553497 FALSE 634.3 Ectopic pregnancy Female 19 138 12 pregnancy complications royalblue4 138, 19 35, 4 34, 7 34, 3 35, 5 0.09 0.235 0.702 0.1535 1.09 0.69 1.74 0.684 0.657 0.298 0.5261 1.98 0.547 7.19 0.0563 0.767 0.941 0.02621 1.06 0.235 4.76 0.373 0.658 0.57 0.2439 1.45 0.4 5.27 PRS_PLINK_0.00398107170553497 TRUE 635 Hemorrhage during pregnancy; childbirth and postpartum Female 150 666 12 pregnancy complications royalblue4 666, 150 167, 31 166, 35 166, 43 167, 41 0.147 0.0939 0.119 0.9257 1.16 0.963 1.39 0.156 0.268 0.562 0.2504 1.17 0.691 1.98 0.286 0.262 0.275 0.5609 1.33 0.796 2.23 0.288 0.269 0.283 0.548 1.33 0.788 2.26 PRS_PLINK_0.00398107170553497 FALSE 635.2 Antepartum hemorrhage, abruptio placentae, and placenta previa Female 105 462 12 pregnancy complications royalblue4 462, 105 116, 23 115, 21 115, 30 116, 31 0.167 0.114 0.143 0.8444 1.18 0.945 1.48 -0.0485 0.326 0.882 0.05469 0.953 0.503 1.8 0.328 0.316 0.3 0.5227 1.39 0.747 2.58 0.365 0.315 0.246 0.6093 1.44 0.778 2.67 PRS_PLINK_0.00398107170553497 FALSE 635.3 Placenta previa and abruptio placenta Female 72 325 12 pregnancy complications royalblue4 325, 72 82, 16 81, 16 81, 20 81, 20 0.108 0.135 0.424 0.3727 1.11 0.855 1.45 0.0406 0.377 0.914 0.03898 1.04 0.498 2.18 0.133 0.378 0.724 0.14 1.14 0.545 2.4 0.197 0.367 0.592 0.2279 1.22 0.593 2.5 PRS_PLINK_0.00398107170553497 FALSE 636 Early or threatened labor; hemorrhage in early pregnancy Female 277 1023 12 pregnancy complications royalblue4 1023, 277 256, 55 256, 58 255, 76 256, 88 0.211 0.0697 0.00249 2.604 1.23 1.08 1.42 0.0639 0.21 0.761 0.1185 1.07 0.706 1.61 0.289 0.202 0.152 0.8189 1.34 0.899 1.98 0.448 0.198 0.024 1.621 1.57 1.06 2.31 PRS_PLINK_0.00398107170553497 FALSE 636.1 Threatened premature labor Female 100 451 12 pregnancy complications royalblue4 451, 100 113, 19 113, 23 112, 23 113, 35 0.284 0.117 0.0153 1.814 1.33 1.06 1.67 0.261 0.344 0.448 0.349 1.3 0.662 2.55 0.174 0.337 0.605 0.2185 1.19 0.615 2.3 0.528 0.319 0.0978 1.01 1.7 0.908 3.17 PRS_PLINK_0.00398107170553497 FALSE 636.2 Early onset of delivery Female 74 369 12 pregnancy complications royalblue4 369, 74 93, 18 92, 12 92, 21 92, 23 0.243 0.133 0.0671 1.173 1.27 0.983 1.65 -0.334 0.401 0.405 0.3928 0.716 0.326 1.57 0.168 0.367 0.647 0.1892 1.18 0.576 2.43 0.49 0.365 0.179 0.7463 1.63 0.798 3.34 PRS_PLINK_0.00398107170553497 FALSE 636.3 Hemorrhage in early pregnancy Female 112 565 12 pregnancy complications royalblue4 565, 112 142, 27 141, 29 141, 27 141, 29 0.0482 0.107 0.651 0.1862 1.05 0.851 1.29 0.0281 0.299 0.925 0.03381 1.03 0.572 1.85 -0.0303 0.302 0.92 0.03614 0.97 0.536 1.75 -0.036 0.304 0.906 0.04301 0.965 0.532 1.75 PRS_PLINK_0.00398107170553497 FALSE 636.8 Cervical incompetence Female 16 97 12 pregnancy complications royalblue4 97, 16 25, 5 24, 4 24, 3 24, 4 0.0523 0.292 0.858 0.06662 1.05 0.595 1.87 0.98 0.969 0.312 0.5063 2.66 0.399 17.8 -0.615 0.838 0.463 0.3347 0.541 0.105 2.79 -0.0363 0.743 0.961 0.01725 0.964 0.225 4.14 PRS_PLINK_0.00398107170553497 TRUE 637 Short gestation; low birth weight; and fetal growth retardation Both 12 80 12 pregnancy complications royalblue4 80, 12 20, 2 20, 4 20, 1 20, 5 0.256 0.324 0.429 0.3671 1.29 0.684 2.44 0.231 0.905 0.799 0.09769 1.26 0.214 7.43 -1.05 1.15 0.359 0.4446 0.35 0.037 3.31 1.01 0.851 0.233 0.6325 2.76 0.521 14.6 PRS_PLINK_0.00398107170553497 TRUE 642 Hypertension complicating pregnancy, childbirth, and the puerperium Female 130 870 12 pregnancy complications royalblue4 870, 130 218, 29 217, 28 217, 38 218, 35 0.084 0.0953 0.378 0.4227 1.09 0.902 1.31 -0.103 0.279 0.713 0.1471 0.903 0.523 1.56 0.288 0.266 0.279 0.5546 1.33 0.792 2.24 0.147 0.273 0.59 0.2295 1.16 0.679 1.98 PRS_PLINK_0.00398107170553497 FALSE 642.1 Preeclampsia and eclampsia Female 72 474 12 pregnancy complications royalblue4 474, 72 119, 16 118, 18 118, 20 119, 18 -0.0342 0.131 0.794 0.1 0.966 0.747 1.25 -0.0687 0.375 0.855 0.06821 0.934 0.448 1.95 0.171 0.364 0.638 0.1951 1.19 0.581 2.42 0.16 0.382 0.676 0.1701 1.17 0.555 2.48 PRS_PLINK_0.00398107170553497 FALSE 643 Excessive vomiting in pregnancy Female 61 350 12 pregnancy complications royalblue4 350, 61 88, 13 87, 16 87, 14 88, 18 0.196 0.147 0.182 0.7407 1.22 0.912 1.62 0.199 0.391 0.61 0.2146 1.22 0.567 2.63 0.0232 0.407 0.954 0.02024 1.02 0.461 2.27 0.29 0.386 0.452 0.3448 1.34 0.627 2.85 PRS_PLINK_0.00398107170553497 FALSE 643.1 Hyperemesis gravidarum Female 33 175 12 pregnancy complications royalblue4 175, 33 44, 5 44, 11 43, 7 44, 10 0.254 0.205 0.215 0.6668 1.29 0.863 1.93 0.719 0.604 0.234 0.6307 2.05 0.628 6.71 0.158 0.592 0.79 0.1024 1.17 0.367 3.73 0.562 0.571 0.324 0.4889 1.75 0.573 5.37 PRS_PLINK_0.00398107170553497 TRUE 644 Anemia during pregnancy Female 53 303 12 pregnancy complications royalblue4 303, 53 76, 12 76, 9 75, 16 76, 16 0.151 0.148 0.309 0.5106 1.16 0.87 1.55 -0.336 0.473 0.478 0.3206 0.715 0.283 1.81 0.208 0.415 0.617 0.2097 1.23 0.545 2.78 0.262 0.415 0.528 0.2773 1.3 0.576 2.93 PRS_PLINK_0.00398107170553497 FALSE 646 Other complications of pregnancy NEC Female 202 807 12 pregnancy complications royalblue4 807, 202 202, 45 202, 53 201, 45 202, 59 0.0961 0.0778 0.217 0.6634 1.1 0.945 1.28 0.153 0.228 0.501 0.2999 1.17 0.746 1.82 -0.0082 0.236 0.972 0.01219 0.992 0.624 1.58 0.241 0.229 0.292 0.5346 1.27 0.813 1.99 PRS_PLINK_0.00398107170553497 FALSE 647 Infectious and parasitic complications affecting pregnancy Female 61 323 12 pregnancy complications royalblue4 323, 61 81, 16 81, 16 80, 13 81, 16 0.0532 0.149 0.72 0.1425 1.05 0.788 1.41 0.114 0.387 0.769 0.1139 1.12 0.525 2.39 -0.119 0.418 0.776 0.1099 0.888 0.391 2.02 0.0432 0.415 0.917 0.0376 1.04 0.463 2.35 PRS_PLINK_0.00398107170553497 FALSE 647.1 Infections of genitourinary tract during pregnancy Female 49 284 12 pregnancy complications royalblue4 284, 49 71, 18 71, 8 71, 11 71, 12 -0.131 0.157 0.403 0.3947 0.877 0.645 1.19 -0.835 0.457 0.0679 1.168 0.434 0.177 1.06 -0.459 0.417 0.271 0.5667 0.632 0.279 1.43 -0.409 0.404 0.311 0.5073 0.664 0.301 1.47 PRS_PLINK_0.00398107170553497 TRUE 647.3 Major puerperal infection Female 19 89 12 pregnancy complications royalblue4 89, 19 23, 6 22, 6 22, 5 22, 2 -0.205 0.244 0.401 0.3967 0.815 0.505 1.31 0.646 0.773 0.403 0.3944 1.91 0.42 8.67 0.126 0.745 0.866 0.06258 1.13 0.264 4.88 -1.4 0.949 0.139 0.8568 0.246 0.0383 1.58 PRS_PLINK_0.00398107170553497 TRUE 649 Other conditions or status of the mother complicating pregnancy, childbirth, or the puerperium Female 317 1031 12 pregnancy complications royalblue4 1031, 317 258, 68 258, 83 257, 85 258, 81 0.0859 0.0655 0.19 0.721 1.09 0.958 1.24 0.245 0.19 0.197 0.7054 1.28 0.881 1.85 0.219 0.19 0.251 0.601 1.24 0.857 1.81 0.082 0.194 0.673 0.1721 1.09 0.742 1.59 PRS_PLINK_0.00398107170553497 FALSE 649.1 Diabetes or abnormal glucose tolerance complicating pregnancy Female 170 879 12 pregnancy complications royalblue4 879, 170 220, 51 220, 46 219, 41 220, 32 -0.15 0.0863 0.0821 1.086 0.861 0.727 1.02 -0.067 0.231 0.772 0.1126 0.935 0.595 1.47 -0.153 0.238 0.522 0.2825 0.858 0.538 1.37 -0.572 0.258 0.0264 1.579 0.564 0.34 0.935 PRS_PLINK_0.00398107170553497 FALSE 653 Problems associated with amniotic cavity and membranes Female 144 739 12 pregnancy complications royalblue4 739, 144 185, 34 185, 35 184, 34 185, 41 0.116 0.0925 0.21 0.6784 1.12 0.937 1.35 0.0896 0.261 0.732 0.1356 1.09 0.655 1.83 0.014 0.264 0.958 0.0187 1.01 0.604 1.7 0.22 0.261 0.4 0.3984 1.25 0.747 2.08 PRS_PLINK_0.00398107170553497 FALSE 654.1 Abnormality of organs and soft tissues of pelvis complicating pregnancy, childbirth, or the puerperium Female 50 259 12 pregnancy complications royalblue4 259, 50 65, 15 65, 12 64, 7 65, 16 -0.0313 0.166 0.851 0.0703 0.969 0.7 1.34 -0.44 0.442 0.319 0.4955 0.644 0.271 1.53 -1.03 0.51 0.0433 1.363 0.357 0.131 0.969 -0.0181 0.424 0.966 0.01506 0.982 0.428 2.25 PRS_PLINK_0.00398107170553497 TRUE 654.2 Rhesus isoimmunization in pregnancy Female 53 254 12 pregnancy complications royalblue4 254, 53 64, 11 63, 13 63, 13 64, 16 0.277 0.155 0.0742 1.13 1.32 0.973 1.79 0.186 0.448 0.678 0.1685 1.2 0.5 2.9 0.472 0.459 0.304 0.5177 1.6 0.652 3.94 0.458 0.436 0.293 0.5327 1.58 0.673 3.71 PRS_PLINK_0.00398107170553497 FALSE 655 Known or suspected fetal abnormality affecting management of mother Female 435 1364 12 pregnancy complications royalblue4 1364, 435 341, 87 341, 115 341, 119 341, 114 0.126 0.0565 0.0259 1.587 1.13 1.02 1.27 0.326 0.165 0.0481 1.318 1.38 1 1.91 0.331 0.165 0.0449 1.348 1.39 1.01 1.92 0.258 0.168 0.125 0.9022 1.29 0.931 1.8 PRS_PLINK_0.00398107170553497 FALSE 655.1 Abnormality in fetal heart rate or rhythm Female 168 666 12 pregnancy complications royalblue4 666, 168 167, 40 166, 44 166, 42 167, 42 0.044 0.0879 0.616 0.2101 1.05 0.88 1.24 0.0999 0.248 0.687 0.1631 1.11 0.68 1.8 0.0765 0.251 0.76 0.119 1.08 0.66 1.76 -0.00851 0.254 0.973 0.01179 0.992 0.603 1.63 PRS_PLINK_0.00398107170553497 FALSE 656 Other perinatal conditions of fetus or newborn Both 203 830 12 pregnancy complications royalblue4 830, 203 208, 52 207, 45 207, 49 208, 57 0.11 0.0804 0.173 0.763 1.12 0.953 1.31 -0.0691 0.227 0.761 0.1188 0.933 0.598 1.46 -0.0144 0.229 0.95 0.02244 0.986 0.63 1.54 0.142 0.221 0.522 0.2825 1.15 0.747 1.78 PRS_PLINK_0.00398107170553497 FALSE 656.2 Respiratory conditions of fetus and newborn Both 10 64 12 pregnancy complications royalblue4 64, 10 16, 2 16, 1 16, 5 16, 2 0.542 0.42 0.197 0.7056 1.72 0.755 3.91 0.124 1.26 0.922 0.03544 1.13 0.0966 13.3 1.59 1.21 0.189 0.7242 4.92 0.457 53 1.19 1.28 0.354 0.4515 3.28 0.267 40.2 PRS_PLINK_0.00398107170553497 TRUE 669 Complications of labor and delivery NEC Female 203 906 12 pregnancy complications royalblue4 906, 203 227, 58 226, 46 226, 46 227, 53 -0.00308 0.0764 0.968 0.01421 0.997 0.858 1.16 -0.181 0.22 0.41 0.3874 0.834 0.543 1.28 -0.188 0.22 0.392 0.4067 0.828 0.538 1.28 -0.0913 0.216 0.673 0.1719 0.913 0.597 1.39 PRS_PLINK_0.00398107170553497 FALSE 671 Venous/cerebrovascular complications embolism in pregnancy and the puerperium Female 61 335 12 pregnancy complications royalblue4 335, 61 84, 15 84, 11 83, 18 84, 17 0.063 0.141 0.656 0.1834 1.07 0.807 1.4 -0.221 0.43 0.607 0.2165 0.802 0.345 1.86 0.23 0.399 0.564 0.2486 1.26 0.576 2.75 0.261 0.399 0.512 0.2907 1.3 0.594 2.84 PRS_PLINK_0.00398107170553497 FALSE 674 Other complications of the puerperium NEC Female 34 220 12 pregnancy complications royalblue4 220, 34 55, 12 55, 4 55, 10 55, 8 -0.122 0.178 0.494 0.3066 0.885 0.625 1.25 -0.964 0.558 0.0841 1.075 0.382 0.128 1.14 -0.145 0.466 0.755 0.1218 0.865 0.347 2.15 -0.158 0.52 0.761 0.1187 0.854 0.308 2.36 PRS_PLINK_0.00398107170553497 TRUE 676 Other disorders of the breast associated with childbirth and disorders of lactation Female 55 266 12 pregnancy complications royalblue4 266, 55 67, 9 66, 12 66, 16 67, 18 0.268 0.154 0.0808 1.093 1.31 0.968 1.77 0.143 0.457 0.755 0.1222 1.15 0.471 2.83 0.635 0.455 0.163 0.7865 1.89 0.773 4.61 0.673 0.444 0.129 0.8885 1.96 0.822 4.68 PRS_PLINK_0.00398107170553497 FALSE 681 Superficial cellulitis and abscess Both 1060 3818 13 dermatologic firebrick 3818, 1060 954, 234 954, 290 954, 264 955, 272 0.0429 0.0359 0.232 0.6337 1.04 0.973 1.12 0.205 0.101 0.0416 1.381 1.23 1.01 1.5 0.104 0.104 0.314 0.5027 1.11 0.906 1.36 0.134 0.105 0.202 0.6938 1.14 0.93 1.41 PRS_PLINK_0.00398107170553497 FALSE 681.1 Cellulitis and abscess of fingers/toes Both 244 1368 13 dermatologic firebrick 1368, 244 342, 60 342, 55 342, 58 342, 71 0.0619 0.0731 0.397 0.401 1.06 0.922 1.23 -0.0628 0.205 0.759 0.1198 0.939 0.629 1.4 -0.124 0.207 0.549 0.2604 0.883 0.589 1.32 0.13 0.204 0.523 0.2813 1.14 0.764 1.7 PRS_PLINK_0.00398107170553497 FALSE 681.2 Cellulitis and abscess of face/neck Both 166 1022 13 dermatologic firebrick 1022, 166 256, 37 255, 49 255, 45 256, 35 -0.0317 0.0868 0.715 0.1457 0.969 0.817 1.15 0.253 0.236 0.285 0.5448 1.29 0.81 2.05 0.312 0.249 0.21 0.6769 1.37 0.838 2.23 0.047 0.26 0.856 0.06728 1.05 0.63 1.74 PRS_PLINK_0.00398107170553497 FALSE 681.3 Cellulitis and abscess of arm/hand Both 357 2096 13 dermatologic firebrick 2096, 357 524, 96 524, 94 524, 83 524, 84 -0.0542 0.0588 0.356 0.448 0.947 0.844 1.06 -0.0468 0.159 0.768 0.1145 0.954 0.699 1.3 -0.192 0.167 0.248 0.605 0.825 0.595 1.14 -0.179 0.167 0.285 0.5449 0.836 0.603 1.16 PRS_PLINK_0.00398107170553497 FALSE 681.5 Cellulitis and abscess of leg, except foot Both 350 2098 13 dermatologic firebrick 2098, 350 525, 96 524, 88 524, 80 525, 86 -0.0347 0.0596 0.56 0.2516 0.966 0.859 1.09 -0.113 0.162 0.485 0.314 0.893 0.651 1.23 -0.211 0.168 0.208 0.6814 0.81 0.583 1.12 -0.165 0.166 0.321 0.4929 0.848 0.612 1.17 PRS_PLINK_0.00398107170553497 FALSE 681.6 Cellulitis and abscess of foot, toe Both 296 1734 13 dermatologic firebrick 1734, 296 434, 83 433, 73 433, 69 434, 71 -0.0253 0.0643 0.695 0.1583 0.975 0.86 1.11 -0.159 0.177 0.368 0.4338 0.853 0.604 1.21 -0.212 0.181 0.24 0.6197 0.809 0.568 1.15 -0.172 0.181 0.342 0.4665 0.842 0.59 1.2 PRS_PLINK_0.00398107170553497 FALSE 681.7 Cellulitis and abscess of trunk Both 175 1614 13 dermatologic firebrick 1614, 175 403, 40 403, 38 403, 44 404, 53 0.0913 0.082 0.265 0.5762 1.1 0.933 1.29 -0.0614 0.235 0.794 0.1 0.94 0.593 1.49 0.0988 0.231 0.669 0.1748 1.1 0.702 1.74 0.179 0.229 0.435 0.3612 1.2 0.763 1.87 PRS_PLINK_0.00398107170553497 FALSE 686 Other local infections of skin and subcutaneous tissue Both 371 2243 13 dermatologic firebrick 2243, 371 561, 103 561, 98 560, 78 561, 92 -0.0159 0.0575 0.782 0.1066 0.984 0.879 1.1 -0.0528 0.155 0.733 0.1349 0.949 0.701 1.28 -0.333 0.166 0.0445 1.351 0.717 0.518 0.992 -0.139 0.161 0.389 0.41 0.87 0.634 1.19 PRS_PLINK_0.00398107170553497 FALSE 686.1 Carbuncle and furuncle Both 106 715 13 dermatologic firebrick 715, 106 179, 20 179, 26 178, 30 179, 30 0.151 0.111 0.176 0.7556 1.16 0.935 1.45 0.3 0.316 0.344 0.4639 1.35 0.726 2.51 0.396 0.308 0.199 0.7013 1.49 0.812 2.72 0.348 0.307 0.257 0.5906 1.42 0.776 2.59 PRS_PLINK_0.00398107170553497 FALSE 686.2 Impetigo Both 87 519 13 dermatologic firebrick 519, 87 129, 25 130, 20 129, 27 130, 15 -0.148 0.12 0.218 0.6624 0.862 0.681 1.09 -0.141 0.332 0.67 0.1738 0.868 0.453 1.66 0.0129 0.321 0.968 0.01412 1.01 0.54 1.9 -0.578 0.362 0.11 0.9586 0.561 0.276 1.14 PRS_PLINK_0.00398107170553497 FALSE 686.3 Pilonidal cyst Both 25 171 13 dermatologic firebrick 171, 25 43, 9 43, 6 42, 4 43, 6 -0.0696 0.219 0.751 0.1246 0.933 0.607 1.43 -0.233 0.618 0.706 0.1513 0.792 0.236 2.66 -0.568 0.682 0.405 0.3927 0.567 0.149 2.16 -0.196 0.605 0.747 0.1269 0.822 0.251 2.69 PRS_PLINK_0.00398107170553497 TRUE 686.4 Pyogenic granuloma Both 34 194 13 dermatologic firebrick 194, 34 49, 7 48, 9 48, 9 49, 9 0.041 0.199 0.837 0.07727 1.04 0.705 1.54 0.387 0.542 0.475 0.3235 1.47 0.509 4.26 0.447 0.55 0.416 0.3807 1.56 0.532 4.6 -0.036 0.618 0.953 0.02069 0.965 0.288 3.24 PRS_PLINK_0.00398107170553497 TRUE 686.5 Pyoderma Both 13 71 13 dermatologic firebrick 71, 13 18, 3 18, 5 17, 2 18, 3 -0.0723 0.276 0.793 0.1006 0.93 0.542 1.6 -0.13 0.87 0.881 0.0549 0.878 0.159 4.84 -0.494 0.989 0.617 0.2094 0.61 0.0878 4.24 0.0413 0.901 0.963 0.01617 1.04 0.178 6.09 PRS_PLINK_0.00398107170553497 TRUE 687 Symptoms affecting skin Both 392 1607 13 dermatologic firebrick 1607, 392 402, 110 402, 94 401, 96 402, 92 -0.0592 0.0584 0.311 0.5075 0.943 0.841 1.06 -0.152 0.159 0.339 0.4692 0.859 0.628 1.17 -0.156 0.159 0.328 0.4843 0.856 0.626 1.17 -0.179 0.163 0.272 0.5649 0.836 0.608 1.15 PRS_PLINK_0.00398107170553497 FALSE 687.1 Rash and other nonspecific skin eruption Both 1618 2787 13 dermatologic firebrick 2787, 1618 697, 414 697, 412 696, 381 697, 411 0.0133 0.0326 0.682 0.166 1.01 0.951 1.08 0.0163 0.09 0.856 0.06749 1.02 0.852 1.21 -0.0505 0.0919 0.583 0.2346 0.951 0.794 1.14 0.0276 0.0925 0.765 0.1162 1.03 0.858 1.23 PRS_PLINK_0.00398107170553497 FALSE 687.3 Changes in skin texture Both 82 460 13 dermatologic firebrick 460, 82 115, 23 115, 20 115, 13 115, 26 0.0151 0.124 0.903 0.04414 1.02 0.796 1.3 -0.0117 0.342 0.973 0.012 0.988 0.506 1.93 -0.422 0.376 0.262 0.581 0.656 0.314 1.37 0.234 0.328 0.476 0.3228 1.26 0.665 2.4 PRS_PLINK_0.00398107170553497 FALSE 687.4 Disturbance of skin sensation Both 1205 2767 13 dermatologic firebrick 2767, 1205 692, 315 692, 302 691, 277 692, 310 0.00179 0.0359 0.96 0.01763 1 0.934 1.07 -0.0418 0.0989 0.672 0.1724 0.959 0.79 1.16 -0.132 0.102 0.194 0.7131 0.876 0.718 1.07 -0.00904 0.101 0.929 0.03207 0.991 0.813 1.21 PRS_PLINK_0.00398107170553497 FALSE 689 Disorder of skin and subcutaneous tissue NOS Both 2075 3152 13 dermatologic firebrick 3152, 2075 787, 560 788, 506 788, 511 788, 498 -0.0475 0.0299 0.112 0.9521 0.954 0.899 1.01 -0.129 0.0825 0.119 0.9248 0.879 0.748 1.03 -0.104 0.0831 0.209 0.6805 0.901 0.765 1.06 -0.149 0.0851 0.08 1.097 0.862 0.729 1.02 PRS_PLINK_0.00398107170553497 FALSE 690 Erythematosquamous dermatosis Both 1327 2824 13 dermatologic firebrick 2824, 1327 706, 348 706, 332 706, 312 706, 334 -0.00737 0.0353 0.835 0.07843 0.993 0.926 1.06 -0.0631 0.0977 0.518 0.2855 0.939 0.775 1.14 -0.0947 0.1 0.345 0.4622 0.91 0.747 1.11 0.0193 0.1 0.848 0.07174 1.02 0.837 1.24 PRS_PLINK_0.00398107170553497 FALSE 690.1 Seborrheic dermatitis Both 1325 2824 13 dermatologic firebrick 2824, 1325 706, 347 706, 331 706, 312 706, 334 -0.00656 0.0354 0.853 0.06914 0.993 0.927 1.06 -0.0652 0.0979 0.505 0.2964 0.937 0.773 1.13 -0.0921 0.1 0.359 0.4455 0.912 0.749 1.11 0.0214 0.1 0.831 0.08037 1.02 0.839 1.24 PRS_PLINK_0.00398107170553497 FALSE 691 Congenital anomalies of skin Both 103 552 13 dermatologic firebrick 552, 103 138, 29 138, 24 138, 23 138, 27 -0.0411 0.108 0.702 0.1534 0.96 0.777 1.19 -0.142 0.304 0.64 0.1942 0.867 0.478 1.57 -0.176 0.309 0.568 0.2455 0.838 0.457 1.54 -0.142 0.311 0.649 0.1879 0.868 0.472 1.6 PRS_PLINK_0.00398107170553497 FALSE 691.3 Congenital pigmentary anomalies of skin Both 9 59 13 dermatologic firebrick 59, 9 15, 2 15, 2 14, 2 15, 3 0.125 0.359 0.728 0.1377 1.13 0.561 2.29 1.18 1.35 0.379 0.4212 3.27 0.233 45.8 0.574 1.09 0.597 0.2241 1.78 0.211 14.9 0.468 1 0.64 0.1937 1.6 0.224 11.4 PRS_PLINK_0.00398107170553497 TRUE 694 Dyschromia and Vitiligo Both 523 1831 13 dermatologic firebrick 1831, 523 458, 128 458, 140 457, 128 458, 127 -0.0241 0.0511 0.637 0.1957 0.976 0.883 1.08 0.0511 0.14 0.716 0.1454 1.05 0.799 1.39 -0.0327 0.145 0.822 0.08538 0.968 0.728 1.29 -0.00881 0.147 0.952 0.02122 0.991 0.743 1.32 PRS_PLINK_0.00398107170553497 FALSE 694.1 Vitiligo Both 25 152 13 dermatologic firebrick 152, 25 38, 9 38, 8 38, 6 38, 2 -0.497 0.234 0.0337 1.472 0.608 0.384 0.962 -0.393 0.575 0.495 0.3058 0.675 0.219 2.08 -0.525 0.595 0.378 0.4225 0.592 0.184 1.9 -1.48 0.777 0.0573 1.241 0.228 0.0497 1.05 PRS_PLINK_0.00398107170553497 TRUE 694.2 Other dyschromia Both 493 1673 13 dermatologic firebrick 1673, 493 419, 118 418, 132 418, 122 418, 121 -0.0031 0.0527 0.953 0.02085 0.997 0.899 1.11 0.0774 0.146 0.595 0.2253 1.08 0.812 1.44 -0.0197 0.151 0.896 0.04774 0.98 0.73 1.32 0.0118 0.153 0.939 0.0274 1.01 0.749 1.37 PRS_PLINK_0.00398107170553497 FALSE 694.3 Vascular disorders of skin Both 14 77 13 dermatologic firebrick 77, 14 20, 3 19, 2 19, 4 19, 5 0.194 0.346 0.574 0.2408 1.21 0.617 2.39 -0.527 1.01 0.602 0.2205 0.59 0.0815 4.28 0.016 1.02 0.987 0.005481 1.02 0.139 7.45 0.647 0.892 0.468 0.3294 1.91 0.332 11 PRS_PLINK_0.00398107170553497 TRUE 695 Erythematous conditions Both 861 2821 13 dermatologic firebrick 2821, 861 706, 224 705, 233 705, 203 705, 201 -0.0221 0.0406 0.587 0.2317 0.978 0.903 1.06 0.0523 0.111 0.637 0.1958 1.05 0.848 1.31 -0.0759 0.115 0.509 0.2933 0.927 0.74 1.16 -0.0234 0.117 0.841 0.07512 0.977 0.777 1.23 PRS_PLINK_0.00398107170553497 FALSE 695.1 Toxic erythema Both 14 82 13 dermatologic firebrick 82, 14 21, 2 20, 6 20, 1 21, 5 0.3 0.319 0.346 0.4609 1.35 0.723 2.52 1.41 0.973 0.148 0.8283 4.08 0.606 27.4 -0.697 1.15 0.543 0.2649 0.498 0.0525 4.72 0.556 0.897 0.536 0.2711 1.74 0.3 10.1 PRS_PLINK_0.00398107170553497 TRUE 695.2 Bullous dermatoses Both 17 78 13 dermatologic firebrick 78, 17 20, 5 19, 2 19, 5 20, 5 -0.0976 0.27 0.718 0.1441 0.907 0.534 1.54 -0.388 0.882 0.66 0.1807 0.678 0.12 3.82 0.201 0.79 0.799 0.09735 1.22 0.26 5.75 -0.161 0.875 0.854 0.06834 0.852 0.153 4.73 PRS_PLINK_0.00398107170553497 TRUE 695.3 Rosacea Both 474 1862 13 dermatologic firebrick 1862, 474 466, 121 465, 129 465, 112 466, 112 0.014 0.0537 0.794 0.1002 1.01 0.913 1.13 0.0777 0.144 0.591 0.2287 1.08 0.814 1.43 -0.0694 0.15 0.644 0.1908 0.933 0.695 1.25 -0.0121 0.152 0.937 0.02842 0.988 0.734 1.33 PRS_PLINK_0.00398107170553497 FALSE 695.4 Lupus (localized and systemic) Both 136 758 13 dermatologic firebrick 758, 136 190, 37 189, 31 189, 37 190, 31 -0.0187 0.0939 0.842 0.0747 0.981 0.816 1.18 -0.0517 0.268 0.847 0.07196 0.95 0.561 1.61 0.0811 0.259 0.754 0.1225 1.08 0.653 1.8 0.0367 0.285 0.898 0.04694 1.04 0.593 1.81 PRS_PLINK_0.00398107170553497 FALSE 695.41 Cutaneous lupus erythematosus Both 60 276 13 dermatologic firebrick 276, 60 69, 14 69, 12 69, 22 69, 12 -0.0333 0.15 0.825 0.08378 0.967 0.721 1.3 -0.183 0.434 0.674 0.1714 0.833 0.356 1.95 0.441 0.395 0.265 0.5772 1.55 0.716 3.37 0.0328 0.458 0.943 0.02547 1.03 0.421 2.54 PRS_PLINK_0.00398107170553497 FALSE 695.42 Systemic lupus erythematosus Both 128 723 13 dermatologic firebrick 723, 128 181, 35 181, 30 180, 31 181, 32 -0.00372 0.0962 0.969 0.01359 0.996 0.825 1.2 -0.0573 0.274 0.834 0.07883 0.944 0.552 1.61 -0.00718 0.273 0.979 0.009198 0.993 0.581 1.7 0.0441 0.284 0.877 0.05718 1.05 0.599 1.82 PRS_PLINK_0.00398107170553497 FALSE 695.7 Prurigo and Lichen Both 112 649 13 dermatologic firebrick 649, 112 163, 23 162, 38 162, 24 162, 27 0.0145 0.1 0.885 0.05319 1.01 0.834 1.23 0.648 0.294 0.0276 1.559 1.91 1.07 3.4 0.0263 0.315 0.933 0.02992 1.03 0.554 1.9 0.211 0.311 0.497 0.3034 1.23 0.671 2.27 PRS_PLINK_0.00398107170553497 FALSE 695.8 Other specified erythematous conditions Both 158 853 13 dermatologic firebrick 853, 158 214, 43 213, 42 213, 39 213, 34 -0.0797 0.0901 0.376 0.4247 0.923 0.774 1.1 0.00946 0.239 0.968 0.01394 1.01 0.632 1.61 -0.141 0.246 0.566 0.2471 0.868 0.536 1.41 -0.197 0.254 0.437 0.3592 0.821 0.499 1.35 PRS_PLINK_0.00398107170553497 FALSE 695.81 Erythema nodosum Both 14 51 13 dermatologic firebrick 51, 14 13, 6 13, 4 12, 0 13, 4 -0.373 0.315 0.236 0.6266 0.689 0.371 1.28 -0.596 1 0.553 0.2575 0.551 0.0772 3.94 -1.88 1.36 0.166 0.7808 0.152 0.0106 2.18 0.11 0.839 0.896 0.04772 1.12 0.216 5.78 PRS_PLINK_0.00398107170553497 TRUE 695.9 Unspecified erythematous condition Both 109 648 13 dermatologic firebrick 648, 109 162, 33 162, 29 162, 23 162, 24 -0.0572 0.108 0.596 0.2246 0.944 0.764 1.17 -0.0488 0.287 0.865 0.06289 0.952 0.542 1.67 -0.303 0.303 0.318 0.4982 0.739 0.408 1.34 -0.259 0.303 0.392 0.407 0.771 0.426 1.4 PRS_PLINK_0.00398107170553497 FALSE 696 Psoriasis and related disorders Both 263 1262 13 dermatologic firebrick 1262, 263 316, 67 315, 75 315, 58 316, 63 -0.00235 0.0694 0.973 0.01189 0.998 0.871 1.14 0.0804 0.189 0.67 0.1738 1.08 0.749 1.57 -0.204 0.201 0.31 0.5082 0.816 0.55 1.21 -0.00822 0.2 0.967 0.01449 0.992 0.671 1.47 PRS_PLINK_0.00398107170553497 FALSE 696.3 Pityriasis Both 33 91 13 dermatologic firebrick 91, 33 23, 10 23, 7 22, 10 23, 6 -0.063 0.2 0.753 0.1233 0.939 0.635 1.39 -0.273 0.577 0.637 0.1959 0.761 0.246 2.36 0.0884 0.626 0.888 0.05169 1.09 0.32 3.73 -0.374 0.627 0.551 0.2591 0.688 0.201 2.35 PRS_PLINK_0.00398107170553497 TRUE 696.4 Psoriasis Both 234 1183 13 dermatologic firebrick 1183, 234 296, 60 296, 67 295, 52 296, 55 -0.0267 0.0743 0.72 0.1429 0.974 0.842 1.13 0.0234 0.199 0.907 0.0426 1.02 0.693 1.51 -0.207 0.211 0.327 0.4857 0.813 0.538 1.23 -0.0661 0.21 0.753 0.1233 0.936 0.62 1.41 PRS_PLINK_0.00398107170553497 FALSE 696.41 Psoriasis vulgaris Both 224 1085 13 dermatologic firebrick 1085, 224 272, 55 271, 69 271, 49 271, 51 -0.0273 0.0758 0.719 0.1433 0.973 0.839 1.13 0.145 0.204 0.476 0.3222 1.16 0.775 1.73 -0.19 0.22 0.386 0.4129 0.827 0.537 1.27 -0.0527 0.219 0.81 0.09147 0.949 0.617 1.46 PRS_PLINK_0.00398107170553497 FALSE 696.42 Psoriatic arthropathy Both 43 214 13 dermatologic firebrick 214, 43 54, 8 53, 11 53, 12 54, 12 0.162 0.171 0.343 0.4653 1.18 0.841 1.64 0.0758 0.512 0.882 0.05442 1.08 0.396 2.94 0.171 0.554 0.758 0.1205 1.19 0.401 3.51 0.544 0.498 0.275 0.5604 1.72 0.649 4.57 PRS_PLINK_0.00398107170553497 TRUE 697 Sarcoidosis Both 47 313 13 dermatologic firebrick 313, 47 79, 13 78, 12 78, 11 78, 10 -0.236 0.166 0.153 0.8141 0.789 0.571 1.09 0.0175 0.436 0.968 0.01411 1.02 0.433 2.39 0.0289 0.454 0.949 0.02261 1.03 0.423 2.51 -0.199 0.456 0.663 0.1787 0.82 0.336 2 PRS_PLINK_0.00398107170553497 TRUE 698 Pruritus and related conditions Both 533 3004 13 dermatologic firebrick 3004, 533 750, 127 751, 133 751, 141 751, 132 0.0155 0.0483 0.748 0.1261 1.02 0.924 1.12 0.0597 0.135 0.658 0.1814 1.06 0.815 1.38 0.0966 0.135 0.475 0.3229 1.1 0.845 1.44 -0.00513 0.139 0.97 0.01302 0.995 0.758 1.31 PRS_PLINK_0.00398107170553497 FALSE 700 Corns and callosities Both 305 1317 13 dermatologic firebrick 1317, 305 330, 77 329, 69 329, 84 329, 75 0.0109 0.0655 0.868 0.06165 1.01 0.889 1.15 -0.0844 0.185 0.649 0.1879 0.919 0.639 1.32 0.0888 0.181 0.624 0.2047 1.09 0.766 1.56 -0.00421 0.189 0.982 0.007792 0.996 0.688 1.44 PRS_PLINK_0.00398107170553497 FALSE 701 Other hypertrophic and atrophic conditions of skin Both 1549 3499 13 dermatologic firebrick 3499, 1549 874, 386 875, 374 874, 387 875, 402 0.0548 0.0319 0.0859 1.066 1.06 0.992 1.12 -0.0292 0.0893 0.743 0.1288 0.971 0.815 1.16 0.0163 0.0899 0.856 0.06749 1.02 0.852 1.21 0.0968 0.0905 0.285 0.5455 1.1 0.923 1.32 PRS_PLINK_0.00398107170553497 FALSE 701.1 Keratoderma, acquired Both 140 661 13 dermatologic firebrick 661, 140 166, 39 165, 31 165, 36 165, 34 0.00206 0.0972 0.983 0.007402 1 0.828 1.21 -0.074 0.27 0.784 0.1057 0.929 0.547 1.58 0.0366 0.261 0.888 0.05142 1.04 0.622 1.73 0.0706 0.272 0.795 0.09936 1.07 0.629 1.83 PRS_PLINK_0.00398107170553497 FALSE 701.2 Scar conditions and fibrosis of skin Both 390 2225 13 dermatologic firebrick 2225, 390 557, 97 556, 84 556, 110 556, 99 0.0595 0.0571 0.297 0.5268 1.06 0.949 1.19 -0.111 0.161 0.492 0.3082 0.895 0.653 1.23 0.11 0.154 0.476 0.3222 1.12 0.825 1.51 -0.0311 0.161 0.847 0.07209 0.969 0.707 1.33 PRS_PLINK_0.00398107170553497 FALSE 701.3 Circumscribed scleroderma Both 138 765 13 dermatologic firebrick 765, 138 191, 29 191, 45 191, 31 191, 33 0.0879 0.0968 0.364 0.4386 1.09 0.903 1.32 0.4 0.259 0.123 0.9117 1.49 0.898 2.48 0.169 0.276 0.542 0.266 1.18 0.689 2.03 0.236 0.279 0.398 0.4004 1.27 0.732 2.19 PRS_PLINK_0.00398107170553497 FALSE 701.4 Keloid scar Both 117 615 13 dermatologic firebrick 615, 117 154, 29 154, 18 153, 42 154, 28 0.0446 0.108 0.679 0.1679 1.05 0.846 1.29 -0.593 0.333 0.075 1.125 0.553 0.288 1.06 0.367 0.271 0.176 0.7557 1.44 0.849 2.45 0.0706 0.304 0.816 0.08806 1.07 0.591 1.95 PRS_PLINK_0.00398107170553497 FALSE 701.5 Abnormal granulation tissue Both 47 397 13 dermatologic firebrick 397, 47 100, 10 99, 16 99, 9 99, 12 -0.0567 0.152 0.709 0.149 0.945 0.701 1.27 0.478 0.416 0.251 0.6007 1.61 0.714 3.64 -0.242 0.475 0.611 0.2141 0.785 0.31 1.99 0.149 0.453 0.743 0.1291 1.16 0.477 2.82 PRS_PLINK_0.00398107170553497 TRUE 702 Degenerative skin conditions and other dermatoses Both 1752 2430 13 dermatologic firebrick 2430, 1752 608, 464 607, 418 607, 423 608, 446 -0.00308 0.0342 0.928 0.03234 0.997 0.932 1.07 -0.117 0.0948 0.216 0.666 0.889 0.739 1.07 -0.107 0.0961 0.266 0.5747 0.899 0.744 1.08 -0.0646 0.0968 0.504 0.2973 0.937 0.775 1.13 PRS_PLINK_0.00398107170553497 FALSE 702.1 Actinic keratosis Both 1061 2328 13 dermatologic firebrick 2328, 1061 582, 276 582, 260 582, 244 582, 280 -0.0154 0.04 0.7 0.1551 0.985 0.91 1.07 -0.0943 0.109 0.385 0.4141 0.91 0.736 1.13 -0.175 0.112 0.117 0.9322 0.839 0.674 1.04 -0.0594 0.111 0.594 0.2263 0.942 0.758 1.17 PRS_PLINK_0.00398107170553497 FALSE 702.2 Seborrheic keratosis Both 1440 2916 13 dermatologic firebrick 2916, 1440 729, 388 729, 335 729, 344 729, 372 -0.00531 0.0346 0.878 0.05657 0.995 0.93 1.06 -0.158 0.096 0.0987 1.006 0.853 0.707 1.03 -0.124 0.0967 0.201 0.6975 0.884 0.731 1.07 -0.0318 0.0968 0.742 0.1295 0.969 0.801 1.17 PRS_PLINK_0.00398107170553497 FALSE 702.4 Degenerative skin disorders Both 20 112 13 dermatologic firebrick 112, 20 28, 4 28, 4 28, 4 28, 8 0.154 0.287 0.591 0.2283 1.17 0.665 2.05 -0.0519 0.81 0.949 0.02279 0.949 0.194 4.64 -0.0999 0.725 0.89 0.05043 0.905 0.219 3.75 0.0653 0.696 0.925 0.03369 1.07 0.273 4.18 PRS_PLINK_0.00398107170553497 TRUE 703 Diseases of nail, NOS Both 379 1811 13 dermatologic firebrick 1811, 379 453, 101 453, 80 452, 89 453, 109 0.0978 0.0582 0.0932 1.031 1.1 0.984 1.24 -0.221 0.167 0.185 0.7328 0.802 0.579 1.11 -0.161 0.164 0.328 0.4846 0.851 0.617 1.18 0.128 0.161 0.427 0.3696 1.14 0.829 1.56 PRS_PLINK_0.00398107170553497 FALSE 703.1 Ingrowing nail Both 176 1095 13 dermatologic firebrick 1095, 176 274, 41 274, 44 273, 44 274, 47 0.0675 0.0853 0.429 0.3675 1.07 0.905 1.26 -0.0169 0.24 0.944 0.02505 0.983 0.614 1.57 0.0118 0.238 0.961 0.01741 1.01 0.634 1.61 0.331 0.245 0.177 0.7509 1.39 0.861 2.25 PRS_PLINK_0.00398107170553497 FALSE 704 Diseases of hair and hair follicles Both 760 3432 13 dermatologic firebrick 3432, 760 857, 177 858, 195 858, 188 858, 200 0.0322 0.0414 0.437 0.3599 1.03 0.952 1.12 0.0833 0.116 0.471 0.3272 1.09 0.867 1.36 0.000274 0.118 0.998 0.0008038 1 0.794 1.26 0.0581 0.119 0.625 0.2043 1.06 0.84 1.34 PRS_PLINK_0.00398107170553497 FALSE 704.1 Alopecia Both 421 1969 13 dermatologic firebrick 1969, 421 492, 99 492, 106 492, 100 492, 116 0.0619 0.0548 0.259 0.5874 1.06 0.955 1.18 0.0621 0.156 0.69 0.1609 1.06 0.784 1.44 -0.0741 0.159 0.641 0.193 0.929 0.68 1.27 0.0992 0.158 0.531 0.2747 1.1 0.81 1.51 PRS_PLINK_0.00398107170553497 FALSE 704.11 Alopecia Areata Both 18 96 13 dermatologic firebrick 96, 18 24, 6 24, 3 24, 4 24, 5 -0.012 0.262 0.964 0.01612 0.988 0.591 1.65 -0.278 0.731 0.704 0.1526 0.757 0.181 3.17 -0.815 0.771 0.291 0.5362 0.443 0.0976 2.01 0.0298 0.758 0.969 0.01385 1.03 0.233 4.55 PRS_PLINK_0.00398107170553497 TRUE 704.12 Telogen effluvium Both 20 82 13 dermatologic firebrick 82, 20 21, 7 20, 5 20, 4 21, 4 -0.214 0.29 0.46 0.337 0.807 0.458 1.42 -0.672 0.901 0.456 0.3412 0.511 0.0874 2.99 -0.552 0.848 0.515 0.2884 0.576 0.109 3.03 -0.76 0.919 0.409 0.3886 0.468 0.0772 2.84 PRS_PLINK_0.00398107170553497 TRUE 704.2 Hirsutism Both 65 398 13 dermatologic firebrick 398, 65 100, 13 99, 20 99, 17 100, 15 0.0331 0.143 0.816 0.08815 1.03 0.782 1.37 0.632 0.428 0.14 0.8536 1.88 0.813 4.35 0.1 0.425 0.813 0.08974 1.11 0.481 2.54 0.0211 0.424 0.96 0.01754 1.02 0.445 2.35 PRS_PLINK_0.00398107170553497 FALSE 704.8 Other specified diseases of hair and hair follicles Both 355 1866 13 dermatologic firebrick 1866, 355 467, 81 466, 87 466, 95 467, 92 0.0329 0.0613 0.592 0.2278 1.03 0.916 1.17 0.058 0.169 0.731 0.136 1.06 0.761 1.48 0.0798 0.169 0.636 0.1964 1.08 0.778 1.51 0.0649 0.173 0.708 0.1501 1.07 0.76 1.5 PRS_PLINK_0.00398107170553497 FALSE 705 Disorders of sweat glands Both 96 667 13 dermatologic firebrick 667, 96 166, 30 167, 19 166, 26 167, 21 -0.108 0.107 0.313 0.5048 0.897 0.727 1.11 -0.444 0.315 0.158 0.8005 0.642 0.346 1.19 -0.0791 0.29 0.785 0.1051 0.924 0.523 1.63 -0.267 0.307 0.384 0.4161 0.765 0.419 1.4 PRS_PLINK_0.00398107170553497 FALSE 705.1 Dyshidrosis Both 34 179 13 dermatologic firebrick 179, 34 44, 10 45, 5 44, 12 45, 7 0.00556 0.178 0.975 0.01095 1.01 0.709 1.43 -0.564 0.579 0.33 0.4816 0.569 0.183 1.77 0.131 0.5 0.793 0.1007 1.14 0.428 3.04 -0.309 0.539 0.567 0.2464 0.734 0.255 2.11 PRS_PLINK_0.00398107170553497 TRUE 705.3 Hidradenitis Both 22 241 13 dermatologic firebrick 241, 22 61, 7 60, 3 60, 6 60, 6 0.0529 0.221 0.811 0.09093 1.05 0.683 1.63 -0.452 0.661 0.495 0.3056 0.637 0.174 2.33 -0.169 0.561 0.763 0.1172 0.845 0.281 2.54 0.0658 0.567 0.908 0.04207 1.07 0.351 3.25 PRS_PLINK_0.00398107170553497 TRUE 705.8 Hyperhidrosis Both 241 1141 13 dermatologic firebrick 1141, 241 286, 54 285, 52 285, 71 285, 64 0.0888 0.0712 0.212 0.6732 1.09 0.951 1.26 -0.0816 0.215 0.704 0.1522 0.922 0.605 1.4 0.226 0.203 0.264 0.5778 1.25 0.843 1.86 0.138 0.211 0.514 0.2894 1.15 0.759 1.73 PRS_PLINK_0.00398107170553497 FALSE 706 Diseases of sebaceous glands Both 1435 3607 13 dermatologic firebrick 3607, 1435 901, 380 902, 339 901, 374 902, 342 -0.0013 0.0321 0.968 0.01426 0.999 0.938 1.06 -0.07 0.0896 0.434 0.3622 0.932 0.782 1.11 0.0306 0.0891 0.731 0.1359 1.03 0.866 1.23 -0.0319 0.092 0.729 0.1373 0.969 0.809 1.16 PRS_PLINK_0.00398107170553497 FALSE 706.1 Acne Both 664 2360 13 dermatologic firebrick 2360, 664 589, 171 590, 187 590, 159 590, 147 -0.0397 0.0447 0.374 0.4267 0.961 0.88 1.05 0.121 0.122 0.323 0.4906 1.13 0.888 1.43 -0.0785 0.127 0.538 0.2695 0.925 0.72 1.19 -0.0774 0.132 0.558 0.2536 0.925 0.714 1.2 PRS_PLINK_0.00398107170553497 FALSE 706.2 Sebaceous cyst Both 691 2758 13 dermatologic firebrick 2758, 691 690, 187 689, 147 689, 194 690, 163 -0.00568 0.0437 0.897 0.04739 0.994 0.913 1.08 -0.228 0.124 0.0658 1.182 0.796 0.625 1.01 0.0188 0.119 0.875 0.05822 1.02 0.807 1.29 -0.0961 0.124 0.44 0.357 0.908 0.712 1.16 PRS_PLINK_0.00398107170553497 FALSE 706.3 Seborrhea Both 13 63 13 dermatologic firebrick 63, 13 16, 3 16, 2 15, 4 16, 4 0.0205 0.306 0.947 0.02387 1.02 0.56 1.86 0.222 1.06 0.834 0.07895 1.25 0.157 9.9 -0.275 1.07 0.797 0.0987 0.76 0.0939 6.15 0.0925 0.862 0.915 0.0388 1.1 0.203 5.94 PRS_PLINK_0.00398107170553497 TRUE 706.8 Other specified diseases of sebaceous glands Both 385 1653 13 dermatologic firebrick 1653, 385 414, 98 413, 82 413, 97 413, 108 0.0635 0.058 0.273 0.5631 1.07 0.951 1.19 -0.137 0.167 0.412 0.3853 0.872 0.628 1.21 0.038 0.162 0.815 0.08909 1.04 0.756 1.43 0.129 0.164 0.432 0.3641 1.14 0.824 1.57 PRS_PLINK_0.00398107170553497 FALSE 707 Chronic ulcer of skin Both 365 3043 13 dermatologic firebrick 3043, 365 760, 97 761, 88 760, 91 761, 89 -0.021 0.0563 0.709 0.1494 0.979 0.877 1.09 -0.0505 0.157 0.747 0.1265 0.951 0.699 1.29 -0.0361 0.157 0.818 0.08714 0.965 0.709 1.31 -0.0432 0.16 0.787 0.1039 0.958 0.7 1.31 PRS_PLINK_0.00398107170553497 FALSE 707.1 Decubitus ulcer Both 93 820 13 dermatologic firebrick 820, 93 205, 27 205, 22 205, 17 205, 27 0.00638 0.108 0.953 0.02103 1.01 0.815 1.24 -0.184 0.301 0.541 0.2666 0.832 0.462 1.5 -0.412 0.326 0.207 0.6839 0.663 0.35 1.26 0.0255 0.296 0.932 0.03081 1.03 0.574 1.83 PRS_PLINK_0.00398107170553497 FALSE 707.2 Chronic ulcer of leg or foot Both 149 1052 13 dermatologic firebrick 1052, 149 262, 42 263, 34 263, 34 263, 39 -0.0018 0.0874 0.984 0.007177 0.998 0.841 1.18 -0.215 0.252 0.392 0.4062 0.806 0.492 1.32 -0.172 0.255 0.5 0.3012 0.842 0.511 1.39 -0.00199 0.251 0.994 0.002748 0.998 0.61 1.63 PRS_PLINK_0.00398107170553497 FALSE 707.3 Chronic ulcer of unspecified site Both 218 1990 13 dermatologic firebrick 1990, 218 497, 48 497, 61 497, 54 498, 55 0.0587 0.0729 0.421 0.3758 1.06 0.919 1.22 0.254 0.201 0.208 0.6822 1.29 0.868 1.91 0.151 0.209 0.47 0.3275 1.16 0.772 1.75 0.159 0.211 0.452 0.3453 1.17 0.775 1.77 PRS_PLINK_0.00398107170553497 FALSE 709 Diffuse diseases of connective tissue Both 345 1607 13 dermatologic firebrick 1607, 345 402, 92 402, 89 401, 84 402, 79 -0.0204 0.061 0.738 0.1319 0.98 0.869 1.1 -0.00439 0.166 0.979 0.009285 0.996 0.72 1.38 -0.108 0.17 0.525 0.2796 0.898 0.644 1.25 -0.112 0.173 0.517 0.2862 0.894 0.636 1.26 PRS_PLINK_0.00398107170553497 FALSE 709.2 Sicca syndrome Both 119 540 13 dermatologic firebrick 540, 119 135, 35 135, 30 135, 26 135, 28 -0.0223 0.107 0.835 0.07821 0.978 0.793 1.21 -0.159 0.278 0.568 0.246 0.853 0.495 1.47 -0.345 0.291 0.235 0.6282 0.708 0.4 1.25 -0.179 0.289 0.536 0.2706 0.836 0.475 1.47 PRS_PLINK_0.00398107170553497 FALSE 709.3 Systemic sclerosis Both 41 240 13 dermatologic firebrick 240, 41 60, 10 60, 7 60, 14 60, 10 0.0127 0.174 0.942 0.02601 1.01 0.721 1.42 -0.255 0.529 0.63 0.2004 0.775 0.275 2.19 0.564 0.473 0.234 0.6311 1.76 0.695 4.44 -0.0432 0.487 0.929 0.03178 0.958 0.368 2.49 PRS_PLINK_0.00398107170553497 TRUE 709.5 Dermatomyositis Both 21 100 13 dermatologic firebrick 100, 21 25, 6 25, 4 25, 5 25, 6 0.088 0.274 0.748 0.126 1.09 0.638 1.87 -0.169 0.734 0.817 0.08755 0.844 0.2 3.56 -0.284 0.692 0.681 0.1665 0.753 0.194 2.92 0.0787 0.654 0.904 0.04377 1.08 0.301 3.89 PRS_PLINK_0.00398107170553497 TRUE 709.6 Other specified diffuse diseases of connective tissue Both 20 81 13 dermatologic firebrick 81, 20 21, 6 20, 5 20, 1 20, 8 -0.0578 0.267 0.828 0.08179 0.944 0.56 1.59 -1.95 1.12 0.0827 1.082 0.143 0.0158 1.29 0.0835 0.682 0.903 0.04452 1.09 0.286 4.14 PRS_PLINK_0.00398107170553497 TRUE 709.7 Unspecified diffuse connective tissue disease Both 230 1048 13 dermatologic firebrick 1048, 230 262, 61 262, 62 262, 51 262, 55 -0.0114 0.0749 0.879 0.056 0.989 0.854 1.14 0.0442 0.201 0.826 0.08314 1.05 0.705 1.55 -0.18 0.212 0.395 0.403 0.835 0.551 1.27 -0.0525 0.21 0.803 0.09525 0.949 0.628 1.43 PRS_PLINK_0.00398107170553497 FALSE 710 Osteomyelitis, periostitis, and other infections involving bone Both 124 1034 14 musculoskeletal darkolivegreen 1034, 124 259, 30 258, 31 258, 31 259, 32 0.00772 0.0966 0.936 0.02857 1.01 0.834 1.22 0.0726 0.271 0.789 0.103 1.08 0.632 1.83 0.026 0.277 0.925 0.03376 1.03 0.596 1.77 0.125 0.278 0.653 0.1852 1.13 0.657 1.96 PRS_PLINK_0.00398107170553497 FALSE 710.1 Osteomyelitis Both 116 985 14 musculoskeletal darkolivegreen 985, 116 247, 27 246, 30 246, 29 246, 30 -0.00448 0.0995 0.964 0.01589 0.996 0.819 1.21 0.142 0.279 0.612 0.2131 1.15 0.666 1.99 0.031 0.289 0.914 0.03888 1.03 0.586 1.82 0.155 0.291 0.594 0.2264 1.17 0.66 2.07 PRS_PLINK_0.00398107170553497 FALSE 710.11 Acute osteomyelitis Both 45 497 14 musculoskeletal darkolivegreen 497, 45 125, 11 124, 17 124, 4 124, 13 -0.116 0.157 0.462 0.3351 0.891 0.654 1.21 0.455 0.414 0.271 0.5666 1.58 0.701 3.55 -1.07 0.579 0.0638 1.195 0.342 0.11 1.06 0.14 0.432 0.745 0.1277 1.15 0.493 2.68 PRS_PLINK_0.00398107170553497 TRUE 710.12 Chronic osteomyelitis Both 53 427 14 musculoskeletal darkolivegreen 427, 53 107, 13 107, 11 106, 11 107, 18 0.0893 0.157 0.571 0.2437 1.09 0.803 1.49 -0.237 0.438 0.589 0.23 0.789 0.335 1.86 -0.536 0.466 0.25 0.6021 0.585 0.235 1.46 0.185 0.408 0.651 0.1865 1.2 0.541 2.68 PRS_PLINK_0.00398107170553497 FALSE 710.19 Unspecified osteomyelitis Both 110 927 14 musculoskeletal darkolivegreen 927, 110 232, 25 232, 30 231, 26 232, 29 0.00253 0.103 0.981 0.008548 1 0.819 1.23 0.203 0.287 0.48 0.3185 1.22 0.698 2.15 0.00148 0.302 0.996 0.001702 1 0.554 1.81 0.201 0.298 0.499 0.3016 1.22 0.682 2.19 PRS_PLINK_0.00398107170553497 FALSE 711 Arthropathy associated with infections Both 55 339 14 musculoskeletal darkolivegreen 339, 55 85, 17 85, 12 84, 11 85, 15 0.0134 0.145 0.926 0.03316 1.01 0.762 1.35 -0.253 0.445 0.569 0.2449 0.776 0.325 1.86 -0.246 0.434 0.572 0.243 0.782 0.334 1.83 -0.105 0.408 0.797 0.09877 0.9 0.405 2 PRS_PLINK_0.00398107170553497 FALSE 711.1 Pyogenic arthritis Both 35 211 14 musculoskeletal darkolivegreen 211, 35 53, 9 53, 7 52, 8 53, 11 0.0552 0.183 0.763 0.1175 1.06 0.738 1.51 0.351 0.643 0.585 0.2331 1.42 0.403 5.01 0.23 0.589 0.696 0.1572 1.26 0.397 3.99 0.212 0.537 0.693 0.1595 1.24 0.432 3.54 PRS_PLINK_0.00398107170553497 TRUE 712 Infective connective tissue disorders Both 15 151 14 musculoskeletal darkolivegreen 151, 15 38, 3 38, 2 37, 5 38, 5 -0.0488 0.263 0.853 0.06921 0.952 0.569 1.59 -0.172 0.777 0.824 0.08391 0.842 0.184 3.86 0.29 0.713 0.684 0.1648 1.34 0.33 5.41 0.175 0.709 0.805 0.09428 1.19 0.297 4.78 PRS_PLINK_0.00398107170553497 TRUE 713 Arthropathy associated with other disorders classified elsewhere Both 52 361 14 musculoskeletal darkolivegreen 361, 52 91, 12 90, 7 90, 13 90, 20 0.242 0.146 0.0969 1.014 1.27 0.957 1.69 -0.512 0.467 0.274 0.563 0.599 0.24 1.5 0.0673 0.427 0.875 0.05813 1.07 0.463 2.47 0.517 0.394 0.189 0.7225 1.68 0.775 3.63 PRS_PLINK_0.00398107170553497 FALSE 713.5 Arthropathy associated with neurological disorders Both 31 227 14 musculoskeletal darkolivegreen 227, 31 57, 8 57, 2 56, 8 57, 13 0.265 0.187 0.156 0.8057 1.3 0.903 1.88 -1.13 0.689 0.102 0.9896 0.324 0.084 1.25 -0.0981 0.557 0.86 0.06536 0.907 0.304 2.7 0.584 0.513 0.255 0.5929 1.79 0.656 4.91 PRS_PLINK_0.00398107170553497 TRUE 714 Rheumatoid arthritis and other inflammatory polyarthropathies Both 378 1955 14 musculoskeletal darkolivegreen 1955, 378 489, 94 489, 107 488, 75 489, 102 0.00598 0.0592 0.919 0.03645 1.01 0.896 1.13 0.155 0.159 0.33 0.481 1.17 0.855 1.6 -0.254 0.174 0.144 0.8404 0.776 0.552 1.09 0.0595 0.166 0.72 0.1428 1.06 0.767 1.47 PRS_PLINK_0.00398107170553497 FALSE 714.1 Rheumatoid arthritis Both 305 1657 14 musculoskeletal darkolivegreen 1657, 305 415, 78 414, 86 414, 62 414, 79 -0.0133 0.0652 0.839 0.07647 0.987 0.868 1.12 0.1 0.175 0.567 0.2462 1.11 0.784 1.56 -0.26 0.19 0.17 0.7693 0.771 0.531 1.12 -0.0587 0.184 0.75 0.1247 0.943 0.657 1.35 PRS_PLINK_0.00398107170553497 FALSE 714.2 Juvenile rheumatoid arthritis Both 7 74 14 musculoskeletal darkolivegreen 74, 7 19, 1 18, 3 18, 2 19, 1 -0.21 0.423 0.619 0.2084 0.81 0.354 1.86 1.1 1.17 0.349 0.4569 3 0.3 30 0.28 1.12 0.802 0.09567 1.32 0.147 11.9 -0.368 1.1 0.738 0.1322 0.692 0.0807 5.94 PRS_PLINK_0.00398107170553497 TRUE 715 Other inflammatory spondylopathies Both 225 1170 14 musculoskeletal darkolivegreen 1170, 225 293, 53 292, 61 292, 61 293, 50 -0.00891 0.0751 0.906 0.04309 0.991 0.855 1.15 0.193 0.208 0.354 0.4509 1.21 0.807 1.82 0.0501 0.21 0.812 0.09056 1.05 0.696 1.59 -0.0691 0.22 0.754 0.1226 0.933 0.606 1.44 PRS_PLINK_0.00398107170553497 FALSE 715.1 Sacroiliitis NEC Both 57 292 14 musculoskeletal darkolivegreen 292, 57 73, 12 73, 11 73, 19 73, 15 0.0436 0.154 0.777 0.1097 1.04 0.773 1.41 -0.409 0.462 0.376 0.4248 0.664 0.269 1.64 0.338 0.41 0.41 0.3871 1.4 0.627 3.13 -0.0845 0.463 0.855 0.06789 0.919 0.371 2.28 PRS_PLINK_0.00398107170553497 FALSE 715.2 Ankylosing spondylitis Both 26 196 14 musculoskeletal darkolivegreen 196, 26 49, 7 49, 5 49, 5 49, 9 0.251 0.206 0.223 0.6524 1.29 0.858 1.93 -0.0816 0.618 0.895 0.04824 0.922 0.275 3.09 -0.295 0.588 0.616 0.2102 0.745 0.235 2.36 0.439 0.544 0.42 0.3772 1.55 0.534 4.5 PRS_PLINK_0.00398107170553497 TRUE 716 Other arthropathies Both 2131 2897 14 musculoskeletal darkolivegreen 2897, 2131 725, 557 724, 572 724, 495 724, 506 -0.0345 0.0321 0.283 0.5489 0.966 0.907 1.03 -0.0306 0.0874 0.726 0.1388 0.97 0.817 1.15 -0.161 0.0895 0.0719 1.144 0.851 0.714 1.01 -0.107 0.0909 0.241 0.6177 0.899 0.752 1.07 PRS_PLINK_0.00398107170553497 FALSE 716.1 Unspecified polyarthropathy or polyarthritis Both 39 217 14 musculoskeletal darkolivegreen 217, 39 55, 10 54, 9 54, 6 54, 14 0.177 0.177 0.315 0.5015 1.19 0.845 1.69 -0.363 0.51 0.477 0.3213 0.696 0.256 1.89 -0.637 0.535 0.234 0.631 0.529 0.185 1.51 0.342 0.484 0.48 0.3189 1.41 0.545 3.64 PRS_PLINK_0.00398107170553497 TRUE 716.2 Unspecified monoarthritis Both 27 124 14 musculoskeletal darkolivegreen 124, 27 31, 3 31, 11 31, 7 31, 6 0.136 0.201 0.497 0.3035 1.15 0.773 1.7 1.02 0.665 0.123 0.9088 2.79 0.757 10.2 0.696 0.688 0.312 0.5054 2.01 0.52 7.73 0.21 0.729 0.773 0.1118 1.23 0.296 5.15 PRS_PLINK_0.00398107170553497 TRUE 716.9 Arthropathy NOS Both 2119 2896 14 musculoskeletal darkolivegreen 2896, 2119 724, 555 724, 566 724, 494 724, 503 -0.0356 0.0321 0.268 0.5717 0.965 0.906 1.03 -0.0412 0.0876 0.638 0.195 0.96 0.808 1.14 -0.164 0.0896 0.0669 1.174 0.849 0.712 1.01 -0.111 0.0911 0.223 0.6526 0.895 0.748 1.07 PRS_PLINK_0.00398107170553497 FALSE 717 Polymyalgia Rheumatica Both 64 333 14 musculoskeletal darkolivegreen 333, 64 83, 16 83, 15 83, 15 83, 18 0.0596 0.136 0.661 0.1796 1.06 0.813 1.39 -0.0387 0.394 0.922 0.03546 0.962 0.445 2.08 -0.0145 0.397 0.971 0.01288 0.986 0.453 2.14 0.187 0.39 0.632 0.1991 1.21 0.561 2.59 PRS_PLINK_0.00398107170553497 FALSE 720 Spinal stenosis Both 617 2581 14 musculoskeletal darkolivegreen 2581, 617 646, 146 645, 165 645, 145 645, 160 -0.00239 0.0476 0.96 0.01771 0.998 0.909 1.1 0.0748 0.132 0.571 0.2437 1.08 0.832 1.4 -0.0738 0.136 0.588 0.231 0.929 0.712 1.21 0.0473 0.135 0.726 0.1388 1.05 0.805 1.37 PRS_PLINK_0.00398107170553497 FALSE 720.1 Spinal stenosis of lumbar region Both 449 2100 14 musculoskeletal darkolivegreen 2100, 449 525, 109 525, 123 525, 106 525, 110 -0.0426 0.055 0.438 0.3584 0.958 0.86 1.07 0.0528 0.15 0.725 0.1397 1.05 0.786 1.41 -0.0744 0.156 0.633 0.1986 0.928 0.684 1.26 -0.0648 0.156 0.678 0.1686 0.937 0.69 1.27 PRS_PLINK_0.00398107170553497 FALSE 721 Spondylosis and allied disorders Both 1092 3020 14 musculoskeletal darkolivegreen 3020, 1092 755, 262 755, 296 755, 268 755, 265 -0.0212 0.0375 0.573 0.2421 0.979 0.91 1.05 0.102 0.103 0.321 0.4929 1.11 0.905 1.36 -0.0189 0.106 0.859 0.06609 0.981 0.797 1.21 -0.0587 0.11 0.592 0.2279 0.943 0.761 1.17 PRS_PLINK_0.00398107170553497 FALSE 721.1 Spondylosis without myelopathy Both 1048 3002 14 musculoskeletal darkolivegreen 3002, 1048 751, 251 750, 282 750, 259 751, 255 -0.0222 0.0382 0.561 0.2512 0.978 0.908 1.05 0.0952 0.105 0.365 0.4376 1.1 0.895 1.35 -0.0133 0.108 0.902 0.04472 0.987 0.798 1.22 -0.0498 0.111 0.655 0.184 0.951 0.765 1.18 PRS_PLINK_0.00398107170553497 FALSE 721.2 Spondylosis with myelopathy Both 127 776 14 musculoskeletal darkolivegreen 776, 127 194, 30 194, 37 194, 32 194, 28 0.014 0.0985 0.887 0.05224 1.01 0.836 1.23 0.266 0.269 0.322 0.4923 1.31 0.771 2.21 0.0495 0.277 0.858 0.06651 1.05 0.611 1.81 -0.0789 0.296 0.79 0.1026 0.924 0.518 1.65 PRS_PLINK_0.00398107170553497 FALSE 721.8 Other allied disorders of spine Both 50 269 14 musculoskeletal darkolivegreen 269, 50 68, 7 67, 15 67, 18 67, 10 0.121 0.162 0.455 0.3416 1.13 0.822 1.55 0.853 0.487 0.0801 1.097 2.35 0.903 6.1 0.973 0.486 0.0451 1.346 2.65 1.02 6.85 0.0745 0.53 0.888 0.05146 1.08 0.381 3.05 PRS_PLINK_0.00398107170553497 TRUE 722 Intervertebral disc disorders Both 1097 3148 14 musculoskeletal darkolivegreen 3148, 1097 787, 253 787, 312 787, 280 787, 252 0.000471 0.0375 0.99 0.004374 1 0.93 1.08 0.18 0.102 0.0778 1.109 1.2 0.98 1.46 0.0612 0.105 0.559 0.2523 1.06 0.866 1.31 -0.0566 0.109 0.604 0.2192 0.945 0.763 1.17 PRS_PLINK_0.00398107170553497 FALSE 722.1 Displacement of intervertebral disc Both 644 2932 14 musculoskeletal darkolivegreen 2932, 644 733, 160 733, 174 733, 172 733, 138 -0.0483 0.0457 0.29 0.5373 0.953 0.871 1.04 0.0519 0.124 0.675 0.1709 1.05 0.827 1.34 0.0072 0.125 0.954 0.02042 1.01 0.788 1.29 -0.243 0.133 0.0667 1.176 0.784 0.604 1.02 PRS_PLINK_0.00398107170553497 FALSE 722.3 Schmorl's nodes Both 18 66 14 musculoskeletal darkolivegreen 66, 18 17, 7 16, 5 16, 2 17, 4 -0.341 0.323 0.291 0.5356 0.711 0.378 1.34 0.00289 0.768 0.997 0.001306 1 0.223 4.52 -1.42 0.98 0.148 0.8303 0.242 0.0355 1.65 -0.65 0.79 0.41 0.3868 0.522 0.111 2.45 PRS_PLINK_0.00398107170553497 TRUE 722.6 Degeneration of intervertebral disc Both 734 2879 14 musculoskeletal darkolivegreen 2879, 734 720, 163 720, 221 719, 183 720, 167 -0.0082 0.0439 0.852 0.06957 0.992 0.91 1.08 0.275 0.119 0.0211 1.675 1.32 1.04 1.66 0.0861 0.125 0.491 0.3093 1.09 0.853 1.39 -0.0214 0.129 0.869 0.06115 0.979 0.76 1.26 PRS_PLINK_0.00398107170553497 FALSE 722.7 Intervertebral disc disorder with myelopathy Both 72 477 14 musculoskeletal darkolivegreen 477, 72 120, 17 119, 21 119, 15 119, 19 -0.0212 0.126 0.867 0.06216 0.979 0.765 1.25 0.175 0.361 0.627 0.2029 1.19 0.588 2.42 -0.109 0.378 0.773 0.1116 0.897 0.427 1.88 -0.166 0.371 0.655 0.1839 0.847 0.409 1.75 PRS_PLINK_0.00398107170553497 FALSE 722.8 Postlaminectomy syndrome Both 61 370 14 musculoskeletal darkolivegreen 370, 61 93, 13 92, 14 92, 13 93, 21 0.124 0.141 0.379 0.4213 1.13 0.859 1.49 0.00199 0.411 0.996 0.001684 1 0.448 2.24 0.0254 0.411 0.951 0.02194 1.03 0.458 2.3 0.544 0.394 0.167 0.7763 1.72 0.796 3.73 PRS_PLINK_0.00398107170553497 FALSE 722.9 Other and unspecified disc disorder Both 326 1894 14 musculoskeletal darkolivegreen 1894, 326 474, 77 473, 89 473, 79 474, 81 0.0312 0.0624 0.618 0.2093 1.03 0.913 1.17 0.179 0.17 0.295 0.5302 1.2 0.856 1.67 -0.0281 0.175 0.873 0.05922 0.972 0.69 1.37 0.0268 0.177 0.88 0.05553 1.03 0.726 1.45 PRS_PLINK_0.00398107170553497 FALSE 723 Other disorders of cervical region Both 183 964 14 musculoskeletal darkolivegreen 964, 183 241, 46 241, 40 241, 50 241, 47 -0.0511 0.0822 0.535 0.2719 0.95 0.809 1.12 -0.155 0.237 0.513 0.29 0.856 0.538 1.36 0.0152 0.229 0.947 0.02369 1.02 0.649 1.59 -0.0854 0.236 0.718 0.144 0.918 0.578 1.46 PRS_PLINK_0.00398107170553497 FALSE 723.1 Torticollis Both 49 241 14 musculoskeletal darkolivegreen 241, 49 61, 12 60, 12 60, 13 60, 12 -0.0243 0.165 0.883 0.05404 0.976 0.706 1.35 -0.103 0.48 0.831 0.0806 0.903 0.353 2.31 0.0424 0.447 0.925 0.03406 1.04 0.434 2.51 -0.108 0.459 0.814 0.08941 0.898 0.365 2.21 PRS_PLINK_0.00398107170553497 TRUE 724 Other and unspecified disorders of back Both 908 3091 14 musculoskeletal darkolivegreen 3091, 908 773, 225 773, 230 772, 234 773, 218 0.00963 0.0393 0.807 0.09329 1.01 0.935 1.09 0.00844 0.109 0.938 0.02765 1.01 0.814 1.25 0.00717 0.11 0.948 0.02311 1.01 0.811 1.25 -0.0567 0.114 0.618 0.2087 0.945 0.756 1.18 PRS_PLINK_0.00398107170553497 FALSE 724.1 Disorders of sacrum Both 605 2495 14 musculoskeletal darkolivegreen 2495, 605 624, 154 624, 157 623, 152 624, 142 -0.00284 0.0474 0.952 0.02126 0.997 0.909 1.09 0.00294 0.129 0.982 0.007957 1 0.779 1.29 -0.0842 0.132 0.523 0.2816 0.919 0.71 1.19 -0.125 0.135 0.358 0.4464 0.883 0.677 1.15 PRS_PLINK_0.00398107170553497 FALSE 724.2 Disorders of coccyx Both 106 468 14 musculoskeletal darkolivegreen 468, 106 117, 25 117, 22 117, 29 117, 30 0.155 0.107 0.148 0.8289 1.17 0.946 1.44 -0.101 0.32 0.753 0.1232 0.904 0.483 1.69 0.14 0.308 0.65 0.1874 1.15 0.629 2.1 0.165 0.308 0.593 0.2272 1.18 0.645 2.15 PRS_PLINK_0.00398107170553497 FALSE 724.8 Other symptoms referable to back Both 181 882 14 musculoskeletal darkolivegreen 882, 181 221, 48 220, 32 220, 51 221, 50 0.03 0.0825 0.716 0.1452 1.03 0.877 1.21 -0.379 0.248 0.126 0.8983 0.685 0.421 1.11 0.0852 0.225 0.705 0.1518 1.09 0.7 1.69 0.036 0.229 0.875 0.05795 1.04 0.661 1.62 PRS_PLINK_0.00398107170553497 FALSE 724.9 Other unspecified back disorders Both 229 1285 14 musculoskeletal darkolivegreen 1285, 229 322, 57 321, 58 321, 60 321, 53 -0.0504 0.0733 0.492 0.3082 0.951 0.824 1.1 0.0177 0.204 0.931 0.03113 1.02 0.682 1.52 0.0133 0.205 0.948 0.02301 1.01 0.677 1.52 -0.067 0.213 0.753 0.1234 0.935 0.617 1.42 PRS_PLINK_0.00398107170553497 FALSE 726 Peripheral enthesopathies and allied syndromes Both 2202 2088 14 musculoskeletal darkolivegreen 2088, 2202 522, 549 522, 557 522, 554 522, 542 -0.00836 0.0327 0.798 0.09777 0.992 0.93 1.06 -0.00523 0.091 0.954 0.02037 0.995 0.832 1.19 0.00435 0.0926 0.963 0.0166 1 0.838 1.2 0.0401 0.0949 0.673 0.1722 1.04 0.864 1.25 PRS_PLINK_0.00398107170553497 FALSE 726.1 Enthesopathy Both 1748 2077 14 musculoskeletal darkolivegreen 2077, 1748 520, 442 519, 452 519, 432 519, 422 -0.0336 0.0347 0.333 0.4781 0.967 0.903 1.03 -0.00725 0.0964 0.94 0.02686 0.993 0.822 1.2 -0.0288 0.0982 0.769 0.114 0.972 0.801 1.18 -0.0169 0.101 0.867 0.06199 0.983 0.806 1.2 PRS_PLINK_0.00398107170553497 FALSE 726.2 Synoviopathy Both 214 745 14 musculoskeletal darkolivegreen 745, 214 187, 51 186, 53 186, 56 186, 54 -0.0136 0.0816 0.867 0.06192 0.986 0.841 1.16 0.0278 0.231 0.904 0.04369 1.03 0.654 1.62 0.00495 0.233 0.983 0.007442 1 0.637 1.59 0.076 0.236 0.748 0.1263 1.08 0.679 1.71 PRS_PLINK_0.00398107170553497 FALSE 726.3 Bursitis Both 440 1333 14 musculoskeletal darkolivegreen 1333, 440 334, 111 333, 108 333, 113 333, 108 -0.0199 0.0574 0.728 0.1376 0.98 0.876 1.1 -0.0548 0.159 0.731 0.1361 0.947 0.693 1.29 -0.0379 0.161 0.814 0.08926 0.963 0.702 1.32 -0.00658 0.167 0.969 0.01386 0.993 0.716 1.38 PRS_PLINK_0.00398107170553497 FALSE 726.4 Calcaneal spur; Exostosis NOS Both 280 960 14 musculoskeletal darkolivegreen 960, 280 240, 70 240, 61 240, 89 240, 60 -0.0214 0.0694 0.758 0.1206 0.979 0.854 1.12 -0.194 0.202 0.337 0.4724 0.823 0.554 1.22 0.153 0.19 0.42 0.3766 1.17 0.803 1.69 -0.141 0.208 0.496 0.3048 0.868 0.578 1.3 PRS_PLINK_0.00398107170553497 FALSE 727 Other disorders of synovium, tendon, and bursa Both 1629 2075 14 musculoskeletal darkolivegreen 2075, 1629 519, 387 519, 407 518, 432 519, 402 0.00708 0.0356 0.842 0.07464 1.01 0.939 1.08 0.0196 0.0997 0.844 0.07372 1.02 0.839 1.24 0.0968 0.101 0.335 0.4744 1.1 0.905 1.34 0.0845 0.104 0.416 0.381 1.09 0.888 1.33 PRS_PLINK_0.00398107170553497 FALSE 727.1 Synovitis and tenosynovitis Both 734 1874 14 musculoskeletal darkolivegreen 1874, 734 469, 175 468, 183 468, 193 469, 182 -0.00753 0.0457 0.869 0.061 0.992 0.908 1.09 0.0106 0.129 0.934 0.02958 1.01 0.785 1.3 0.05 0.13 0.702 0.1539 1.05 0.814 1.36 0.0645 0.134 0.63 0.201 1.07 0.821 1.39 PRS_PLINK_0.00398107170553497 FALSE 727.2 Bursitis disorders Both 109 355 14 musculoskeletal darkolivegreen 355, 109 89, 22 89, 29 88, 30 89, 28 0.0382 0.121 0.752 0.1237 1.04 0.82 1.32 0.247 0.336 0.463 0.3343 1.28 0.662 2.47 0.329 0.331 0.321 0.4939 1.39 0.726 2.66 0.204 0.352 0.563 0.2496 1.23 0.615 2.44 PRS_PLINK_0.00398107170553497 FALSE 727.4 Ganglion and cyst of synovium, tendon, and bursa Both 396 1113 14 musculoskeletal darkolivegreen 1113, 396 279, 91 278, 98 278, 121 278, 86 0.0491 0.0614 0.423 0.3732 1.05 0.931 1.18 0.0585 0.177 0.74 0.1305 1.06 0.75 1.5 0.249 0.168 0.139 0.8561 1.28 0.922 1.78 0.0437 0.185 0.814 0.08955 1.04 0.727 1.5 PRS_PLINK_0.00398107170553497 FALSE 727.5 Rupture of synovium Both 130 387 14 musculoskeletal darkolivegreen 387, 130 97, 41 97, 27 96, 32 97, 30 -0.123 0.105 0.238 0.6228 0.884 0.72 1.09 -0.465 0.3 0.12 0.919 0.628 0.349 1.13 -0.236 0.283 0.404 0.394 0.79 0.454 1.37 -0.304 0.29 0.296 0.5293 0.738 0.418 1.3 PRS_PLINK_0.00398107170553497 FALSE 727.6 Rupture of tendon, nontraumatic Both 520 1413 14 musculoskeletal darkolivegreen 1413, 520 354, 129 353, 127 353, 127 353, 137 -0.0172 0.0537 0.749 0.1255 0.983 0.885 1.09 -0.0221 0.15 0.883 0.05422 0.978 0.729 1.31 -0.0177 0.152 0.907 0.04236 0.982 0.73 1.32 0.082 0.155 0.596 0.2247 1.09 0.802 1.47 PRS_PLINK_0.00398107170553497 FALSE 727.7 Contracture of tendon (sheath) Both 115 431 14 musculoskeletal darkolivegreen 431, 115 108, 25 108, 29 107, 44 108, 17 -0.064 0.116 0.58 0.2368 0.938 0.748 1.18 0.0531 0.313 0.865 0.06284 1.05 0.571 1.95 0.425 0.301 0.157 0.8035 1.53 0.849 2.76 -0.478 0.357 0.181 0.7422 0.62 0.308 1.25 PRS_PLINK_0.00398107170553497 FALSE 727.8 Plica syndrome Both 13 60 14 musculoskeletal darkolivegreen 60, 13 15, 2 15, 4 15, 1 15, 6 0.553 0.44 0.209 0.6792 1.74 0.733 4.12 0.0703 1.27 0.956 0.01967 1.07 0.0899 12.8 0.284 1.3 0.826 0.0828 1.33 0.105 16.9 1.63 1.37 0.233 0.6321 5.11 0.349 74.9 PRS_PLINK_0.00398107170553497 TRUE 728 Disorders of muscle, ligament, and fascia Both 844 2013 14 musculoskeletal darkolivegreen 2013, 844 504, 215 503, 210 503, 211 503, 208 -0.00344 0.0431 0.936 0.02854 0.997 0.916 1.08 -0.0476 0.121 0.694 0.1586 0.954 0.752 1.21 -0.0516 0.122 0.671 0.1731 0.95 0.748 1.21 0.0604 0.126 0.631 0.1998 1.06 0.83 1.36 PRS_PLINK_0.00398107170553497 FALSE 728.1 Muscular calcification and ossification Both 9 52 14 musculoskeletal darkolivegreen 52, 9 13, 5 13, 0 13, 2 13, 2 -0.357 0.366 0.329 0.4827 0.699 0.341 1.43 -0.99 1.42 0.485 0.3146 0.371 0.0231 5.97 -0.76 1.13 0.5 0.3012 0.468 0.0515 4.25 0.261 1.25 0.834 0.07864 1.3 0.112 15 PRS_PLINK_0.00398107170553497 TRUE 728.2 Laxity of ligament or hypermobility syndrome Both 47 208 14 musculoskeletal darkolivegreen 208, 47 52, 9 52, 12 52, 13 52, 13 0.0965 0.161 0.548 0.2609 1.1 0.804 1.51 0.356 0.481 0.46 0.3375 1.43 0.556 3.67 0.402 0.499 0.421 0.3757 1.49 0.562 3.98 0.503 0.534 0.346 0.4606 1.65 0.58 4.71 PRS_PLINK_0.00398107170553497 TRUE 728.7 Fasciitis Both 694 1781 14 musculoskeletal darkolivegreen 1781, 694 446, 161 445, 170 445, 180 445, 183 0.0496 0.0468 0.289 0.539 1.05 0.959 1.15 0.0417 0.132 0.751 0.1242 1.04 0.805 1.35 0.105 0.132 0.426 0.371 1.11 0.857 1.44 0.162 0.136 0.235 0.6287 1.18 0.9 1.53 PRS_PLINK_0.00398107170553497 FALSE 728.71 Contracture of palmar fascia [Dupuytren's disease] Both 108 312 14 musculoskeletal darkolivegreen 312, 108 78, 17 78, 32 78, 30 78, 29 0.163 0.118 0.168 0.774 1.18 0.934 1.48 0.721 0.361 0.0457 1.34 2.06 1.01 4.17 0.572 0.354 0.106 0.9756 1.77 0.886 3.54 0.779 0.379 0.0398 1.4 2.18 1.04 4.58 PRS_PLINK_0.00398107170553497 FALSE 729 Other disorders of soft tissues Both 624 1895 14 musculoskeletal darkolivegreen 1895, 624 474, 147 474, 164 473, 175 474, 138 -0.0113 0.0485 0.816 0.08805 0.989 0.899 1.09 0.07 0.135 0.605 0.2183 1.07 0.823 1.4 0.106 0.136 0.436 0.361 1.11 0.852 1.45 -0.0534 0.146 0.715 0.1458 0.948 0.712 1.26 PRS_PLINK_0.00398107170553497 FALSE 729.1 Rheumatism, unspecified and fibrositis Both 21 70 14 musculoskeletal darkolivegreen 70, 21 18, 3 17, 8 17, 2 18, 8 0.259 0.237 0.276 0.5597 1.3 0.814 2.06 1.2 0.939 0.201 0.6974 3.33 0.528 21 -0.808 1.03 0.434 0.3629 0.446 0.0589 3.37 0.946 0.837 0.258 0.5877 2.57 0.499 13.3 PRS_PLINK_0.00398107170553497 TRUE 729.3 Panniculitis Both 20 90 14 musculoskeletal darkolivegreen 90, 20 23, 5 22, 5 22, 2 23, 8 0.0258 0.265 0.922 0.0351 1.03 0.611 1.72 -0.0289 0.705 0.967 0.01443 0.972 0.244 3.87 -0.76 0.799 0.341 0.4671 0.468 0.0977 2.24 0.171 0.663 0.796 0.09907 1.19 0.324 4.35 PRS_PLINK_0.00398107170553497 TRUE 729.7 Nontraumatic compartment syndrome Both 8 41 14 musculoskeletal darkolivegreen 41, 8 11, 3 10, 2 10, 2 10, 1 -0.223 0.437 0.61 0.215 0.8 0.34 1.88 -0.76 1.46 0.603 0.2199 0.468 0.0267 8.18 0.803 1.81 0.657 0.1827 2.23 0.0648 76.8 -0.271 2.01 0.893 0.04917 0.763 0.0147 39.5 PRS_PLINK_0.00398107170553497 TRUE 731 Osteitis deformans and osteopathies associated with other disorders classified elsewhere Both 22 184 14 musculoskeletal darkolivegreen 184, 22 46, 6 46, 6 46, 6 46, 4 -0.137 0.247 0.579 0.2372 0.872 0.538 1.41 -0.563 0.709 0.428 0.369 0.57 0.142 2.29 -0.762 0.703 0.278 0.5557 0.467 0.118 1.85 -0.646 0.757 0.394 0.4047 0.524 0.119 2.31 PRS_PLINK_0.00398107170553497 TRUE 732 Osteochondropathies Both 47 298 14 musculoskeletal darkolivegreen 298, 47 75, 14 74, 11 74, 7 75, 15 -0.0249 0.15 0.869 0.06108 0.975 0.726 1.31 -0.185 0.447 0.679 0.1678 0.831 0.346 2 -0.651 0.473 0.169 0.7727 0.521 0.206 1.32 0.0918 0.421 0.827 0.08223 1.1 0.48 2.5 PRS_PLINK_0.00398107170553497 TRUE 732.1 Juvenile osteochondrosis Both 29 166 14 musculoskeletal darkolivegreen 166, 29 42, 7 41, 4 41, 8 42, 10 0.198 0.199 0.319 0.4958 1.22 0.826 1.8 -0.48 0.627 0.444 0.3522 0.619 0.181 2.12 0.291 0.562 0.604 0.2188 1.34 0.445 4.03 0.398 0.543 0.464 0.3334 1.49 0.513 4.32 PRS_PLINK_0.00398107170553497 TRUE 732.7 Osteochondritis dissecans Both 13 65 14 musculoskeletal darkolivegreen 65, 13 17, 3 16, 4 16, 1 16, 5 0.132 0.257 0.607 0.2165 1.14 0.69 1.89 -0.0736 0.968 0.939 0.02715 0.929 0.139 6.19 -1.35 1.11 0.225 0.6481 0.26 0.0295 2.29 0.501 0.849 0.555 0.2554 1.65 0.312 8.72 PRS_PLINK_0.00398107170553497 TRUE 733 Other disorders of bone and cartilage Both 1270 2417 14 musculoskeletal darkolivegreen 2417, 1270 605, 329 604, 299 604, 328 604, 313 -0.00852 0.0393 0.828 0.08176 0.992 0.918 1.07 -0.136 0.112 0.224 0.6497 0.873 0.702 1.09 0.00184 0.11 0.987 0.005817 1 0.807 1.24 0.0409 0.111 0.713 0.1472 1.04 0.838 1.29 PRS_PLINK_0.00398107170553497 FALSE 733.2 Cyst of bone Both 35 163 14 musculoskeletal darkolivegreen 163, 35 41, 14 41, 4 40, 8 41, 9 -0.152 0.219 0.489 0.3105 0.859 0.559 1.32 -1.19 0.62 0.0552 1.258 0.305 0.0904 1.03 -0.415 0.542 0.443 0.3531 0.66 0.228 1.91 -0.176 0.526 0.737 0.1324 0.838 0.299 2.35 PRS_PLINK_0.00398107170553497 TRUE 733.4 Aseptic necrosis of bone Both 78 399 14 musculoskeletal darkolivegreen 399, 78 100, 25 100, 18 99, 16 100, 19 -0.114 0.13 0.382 0.418 0.893 0.692 1.15 -0.154 0.344 0.653 0.185 0.857 0.437 1.68 -0.291 0.37 0.432 0.3641 0.748 0.362 1.55 -0.0722 0.35 0.837 0.07742 0.93 0.468 1.85 PRS_PLINK_0.00398107170553497 FALSE 733.6 Costochondritis Both 88 379 14 musculoskeletal darkolivegreen 379, 88 95, 25 95, 21 94, 25 95, 17 -0.0308 0.126 0.806 0.09349 0.97 0.758 1.24 -0.309 0.346 0.372 0.4295 0.734 0.373 1.45 -0.102 0.331 0.758 0.1205 0.903 0.471 1.73 -0.366 0.373 0.327 0.4858 0.694 0.334 1.44 PRS_PLINK_0.00398107170553497 FALSE 733.8 Malunion and nonunion of fracture Both 109 624 14 musculoskeletal darkolivegreen 624, 109 156, 32 156, 31 156, 17 156, 28 -0.0442 0.111 0.691 0.1607 0.957 0.77 1.19 0.043 0.285 0.88 0.05539 1.04 0.597 1.83 -0.495 0.332 0.136 0.8674 0.61 0.318 1.17 0.0739 0.298 0.804 0.09456 1.08 0.6 1.93 PRS_PLINK_0.00398107170553497 FALSE 733.9 Chondromalacia Both 13 65 14 musculoskeletal darkolivegreen 65, 13 17, 5 16, 3 16, 3 16, 2 -0.406 0.288 0.158 0.8009 0.666 0.379 1.17 -0.553 0.872 0.526 0.279 0.575 0.104 3.18 -0.254 0.839 0.762 0.1178 0.776 0.15 4.02 -0.59 0.905 0.514 0.2891 0.554 0.0941 3.26 PRS_PLINK_0.00398107170553497 TRUE 735 Acquired foot deformities Both 805 3216 14 musculoskeletal darkolivegreen 3216, 805 803, 200 804, 207 804, 199 804, 199 0.0107 0.0406 0.792 0.1012 1.01 0.934 1.09 0.0406 0.112 0.718 0.1441 1.04 0.836 1.3 -0.00922 0.115 0.936 0.02873 0.991 0.791 1.24 -0.0239 0.116 0.837 0.07721 0.976 0.777 1.23 PRS_PLINK_0.00398107170553497 FALSE 735.1 Flat foot Both 116 727 14 musculoskeletal darkolivegreen 727, 116 182, 32 182, 33 181, 21 182, 30 -0.0787 0.0979 0.422 0.375 0.924 0.763 1.12 0.0646 0.271 0.811 0.09075 1.07 0.628 1.81 -0.372 0.304 0.221 0.6554 0.689 0.38 1.25 0.00878 0.281 0.975 0.01096 1.01 0.582 1.75 PRS_PLINK_0.00398107170553497 FALSE 735.2 Acquired toe deformities Both 357 1527 14 musculoskeletal darkolivegreen 1527, 357 382, 85 382, 98 381, 95 382, 79 -0.0123 0.0614 0.842 0.07485 0.988 0.876 1.11 0.134 0.166 0.419 0.3776 1.14 0.826 1.58 0.103 0.169 0.543 0.2648 1.11 0.795 1.54 -0.0546 0.178 0.759 0.1198 0.947 0.668 1.34 PRS_PLINK_0.00398107170553497 FALSE 735.21 Hammer toe (acquired) Both 225 988 14 musculoskeletal darkolivegreen 988, 225 247, 54 247, 55 247, 65 247, 51 -0.022 0.0777 0.777 0.1093 0.978 0.84 1.14 -0.0318 0.217 0.883 0.05392 0.969 0.633 1.48 0.147 0.212 0.488 0.3113 1.16 0.764 1.76 -0.074 0.225 0.742 0.1293 0.929 0.597 1.44 PRS_PLINK_0.00398107170553497 FALSE 735.23 Hallux rigidus Both 118 526 14 musculoskeletal darkolivegreen 526, 118 132, 27 131, 40 131, 26 132, 25 -0.068 0.113 0.549 0.2607 0.934 0.748 1.17 0.426 0.282 0.132 0.8805 1.53 0.88 2.66 -0.0776 0.307 0.801 0.09655 0.925 0.507 1.69 -0.163 0.309 0.599 0.2226 0.85 0.464 1.56 PRS_PLINK_0.00398107170553497 FALSE 735.3 Hallux valgus (Bunion) Both 448 1809 14 musculoskeletal darkolivegreen 1809, 448 452, 107 452, 118 452, 116 452, 107 0.0285 0.0541 0.598 0.223 1.03 0.925 1.14 0.0762 0.15 0.612 0.2129 1.08 0.804 1.45 0.0281 0.152 0.853 0.06909 1.03 0.764 1.38 -0.0362 0.157 0.818 0.08737 0.964 0.709 1.31 PRS_PLINK_0.00398107170553497 FALSE 736 Other acquired deformities of limbs Both 557 2792 14 musculoskeletal darkolivegreen 2792, 557 697, 140 698, 147 698, 135 698, 135 -0.0168 0.0476 0.724 0.1401 0.983 0.896 1.08 0.0292 0.131 0.824 0.08421 1.03 0.796 1.33 -0.0651 0.134 0.628 0.2019 0.937 0.72 1.22 -0.0503 0.136 0.712 0.1474 0.951 0.728 1.24 PRS_PLINK_0.00398107170553497 FALSE 736.1 Acquired deformities of forearm Both 15 84 14 musculoskeletal darkolivegreen 84, 15 21, 7 21, 3 21, 1 21, 4 -0.345 0.273 0.206 0.6856 0.708 0.415 1.21 -0.577 0.758 0.447 0.3499 0.562 0.127 2.48 -1.55 0.96 0.105 0.9769 0.211 0.0322 1.39 -0.227 0.724 0.754 0.1226 0.797 0.193 3.29 PRS_PLINK_0.00398107170553497 TRUE 736.2 Acquired deformities of finger Both 52 189 14 musculoskeletal darkolivegreen 189, 52 48, 17 47, 14 47, 10 47, 11 -0.156 0.161 0.333 0.4778 0.856 0.625 1.17 -0.0512 0.439 0.907 0.04234 0.95 0.402 2.25 -0.613 0.49 0.211 0.6763 0.542 0.208 1.41 -0.491 0.472 0.298 0.5261 0.612 0.243 1.54 PRS_PLINK_0.00398107170553497 FALSE 736.3 Acquired deformities of hip Both 9 45 14 musculoskeletal darkolivegreen 45, 9 12, 5 11, 0 11, 3 11, 1 -0.7 0.55 0.203 0.6916 0.497 0.169 1.46 -3.23 2.03 0.11 0.9568 0.0394 0.000742 2.09 -0.819 1.31 0.531 0.275 0.441 0.0341 5.71 -2.78 1.94 0.152 0.817 0.062 0.00138 2.79 PRS_PLINK_0.00398107170553497 TRUE 736.4 Genu valgum or varum (acquired) Both 61 348 14 musculoskeletal darkolivegreen 348, 61 87, 16 87, 16 87, 11 87, 18 0.0409 0.144 0.776 0.11 1.04 0.786 1.38 0.107 0.383 0.779 0.1083 1.11 0.526 2.36 -0.309 0.414 0.456 0.3414 0.734 0.327 1.65 0.207 0.391 0.596 0.2248 1.23 0.572 2.65 PRS_PLINK_0.00398107170553497 FALSE 736.5 Acquired deformities of knee Both 33 236 14 musculoskeletal darkolivegreen 236, 33 59, 11 59, 6 59, 7 59, 9 -0.0353 0.194 0.856 0.06765 0.965 0.66 1.41 -0.431 0.52 0.408 0.3898 0.65 0.235 1.8 -0.337 0.499 0.499 0.3019 0.714 0.269 1.9 -0.179 0.493 0.716 0.145 0.836 0.318 2.2 PRS_PLINK_0.00398107170553497 TRUE 736.6 Unequal leg length (acquired) Both 83 369 14 musculoskeletal darkolivegreen 369, 83 93, 17 92, 19 92, 21 92, 26 0.117 0.131 0.372 0.4294 1.12 0.87 1.45 0.24 0.369 0.515 0.2883 1.27 0.617 2.62 0.239 0.356 0.501 0.2999 1.27 0.632 2.55 0.421 0.352 0.231 0.6371 1.52 0.765 3.04 PRS_PLINK_0.00398107170553497 FALSE 737 Curvature of spine Both 303 1686 14 musculoskeletal darkolivegreen 1686, 303 422, 61 421, 81 421, 76 422, 85 0.0925 0.064 0.148 0.8286 1.1 0.968 1.24 0.312 0.185 0.0905 1.043 1.37 0.952 1.96 0.182 0.188 0.333 0.4771 1.2 0.83 1.73 0.363 0.189 0.0547 1.262 1.44 0.993 2.08 PRS_PLINK_0.00398107170553497 FALSE 737.1 Kyphosis (acquired) Both 67 473 14 musculoskeletal darkolivegreen 473, 67 119, 12 118, 19 118, 16 118, 20 0.103 0.137 0.449 0.3476 1.11 0.849 1.45 0.425 0.379 0.263 0.5804 1.53 0.727 3.22 0.108 0.405 0.79 0.1021 1.11 0.504 2.46 0.444 0.404 0.272 0.5661 1.56 0.706 3.44 PRS_PLINK_0.00398107170553497 FALSE 737.2 Lordosis (acquired) Both 7 61 14 musculoskeletal darkolivegreen 61, 7 16, 1 15, 2 15, 2 15, 2 0.668 0.511 0.191 0.718 1.95 0.716 5.31 1.01 1.16 0.386 0.4134 2.74 0.28 26.8 1.21 1.25 0.333 0.4779 3.37 0.289 39.3 1.51 1.32 0.252 0.5985 4.51 0.343 59.4 PRS_PLINK_0.00398107170553497 TRUE 737.3 Kyphoscoliosis and scoliosis Both 248 1316 14 musculoskeletal darkolivegreen 1316, 248 329, 50 329, 66 329, 59 329, 73 0.114 0.0714 0.111 0.9554 1.12 0.974 1.29 0.288 0.204 0.159 0.7994 1.33 0.894 1.99 0.149 0.21 0.477 0.3214 1.16 0.77 1.75 0.438 0.205 0.0326 1.486 1.55 1.04 2.32 PRS_PLINK_0.00398107170553497 FALSE 738 Other acquired musculoskeletal deformity Both 370 2360 14 musculoskeletal darkolivegreen 2360, 370 590, 103 590, 101 590, 87 590, 79 -0.0516 0.0567 0.363 0.4405 0.95 0.85 1.06 -0.0123 0.153 0.936 0.02873 0.988 0.731 1.33 -0.187 0.161 0.245 0.6106 0.83 0.605 1.14 -0.273 0.166 0.0998 1.001 0.761 0.55 1.05 PRS_PLINK_0.00398107170553497 FALSE 738.4 Acquired spondylolisthesis Both 186 1093 14 musculoskeletal darkolivegreen 1093, 186 274, 54 273, 54 273, 43 273, 35 -0.159 0.0824 0.0542 1.266 0.853 0.726 1 0.0498 0.212 0.815 0.08903 1.05 0.693 1.59 -0.193 0.226 0.393 0.4054 0.825 0.53 1.28 -0.443 0.241 0.0661 1.18 0.642 0.4 1.03 PRS_PLINK_0.00398107170553497 FALSE 739 Contracture of joint Both 115 617 14 musculoskeletal darkolivegreen 617, 115 155, 31 154, 25 154, 31 154, 28 0.00924 0.1 0.927 0.03306 1.01 0.829 1.23 -0.236 0.296 0.425 0.3718 0.79 0.442 1.41 0.0344 0.282 0.903 0.04435 1.03 0.596 1.8 -0.0847 0.295 0.774 0.1111 0.919 0.515 1.64 PRS_PLINK_0.00398107170553497 FALSE 740 Osteoarthrosis Both 2489 2692 14 musculoskeletal darkolivegreen 2692, 2489 673, 667 673, 641 673, 574 673, 606 -0.0345 0.032 0.281 0.5506 0.966 0.907 1.03 -0.112 0.088 0.204 0.6894 0.894 0.753 1.06 -0.201 0.0899 0.0254 1.596 0.818 0.686 0.976 -0.0894 0.0909 0.325 0.4877 0.914 0.765 1.09 PRS_PLINK_0.00398107170553497 FALSE 740.1 Osteoarthritis; localized Both 1449 2424 14 musculoskeletal darkolivegreen 2424, 1449 606, 388 606, 367 606, 334 606, 359 -0.0574 0.0384 0.135 0.8695 0.944 0.876 1.02 -0.105 0.105 0.318 0.4973 0.9 0.733 1.11 -0.215 0.107 0.0448 1.349 0.806 0.654 0.995 -0.0802 0.107 0.455 0.3415 0.923 0.748 1.14 PRS_PLINK_0.00398107170553497 FALSE 740.11 Osteoarthrosis, localized, primary Both 1325 2335 14 musculoskeletal darkolivegreen 2335, 1325 584, 354 584, 335 583, 306 584, 329 -0.058 0.0396 0.144 0.8422 0.944 0.873 1.02 -0.115 0.108 0.29 0.5372 0.892 0.721 1.1 -0.219 0.111 0.0474 1.324 0.803 0.647 0.998 -0.0998 0.111 0.369 0.4332 0.905 0.728 1.13 PRS_PLINK_0.00398107170553497 FALSE 740.12 Osteoarthrosis, localized, secondary Both 118 566 14 musculoskeletal darkolivegreen 566, 118 142, 39 141, 30 141, 26 142, 23 -0.275 0.11 0.0119 1.923 0.759 0.613 0.941 -0.381 0.279 0.172 0.7638 0.683 0.395 1.18 -0.441 0.285 0.122 0.9141 0.643 0.368 1.13 -0.631 0.299 0.0348 1.458 0.532 0.296 0.956 PRS_PLINK_0.00398107170553497 FALSE 740.2 Osteoarthrosis, generalized Both 445 1176 14 musculoskeletal darkolivegreen 1176, 445 294, 123 294, 114 294, 97 294, 111 -0.119 0.0636 0.0619 1.208 0.888 0.784 1.01 -0.211 0.169 0.212 0.674 0.81 0.581 1.13 -0.401 0.175 0.0222 1.654 0.67 0.475 0.944 -0.271 0.17 0.112 0.9519 0.763 0.546 1.06 PRS_PLINK_0.00398107170553497 FALSE 740.3 Osteoarthrosis involving more than one site, but not specified as generalized Both 100 381 14 musculoskeletal darkolivegreen 381, 100 96, 28 95, 30 95, 22 95, 20 -0.204 0.125 0.101 0.9963 0.815 0.639 1.04 0.027 0.31 0.931 0.03121 1.03 0.56 1.89 -0.256 0.33 0.437 0.3593 0.774 0.405 1.48 -0.436 0.341 0.201 0.6963 0.647 0.332 1.26 PRS_PLINK_0.00398107170553497 FALSE 740.9 Osteoarthrosis NOS Both 2392 2681 14 musculoskeletal darkolivegreen 2681, 2392 671, 641 670, 617 670, 551 670, 582 -0.0345 0.0325 0.288 0.5411 0.966 0.907 1.03 -0.112 0.0892 0.209 0.6793 0.894 0.751 1.06 -0.207 0.0912 0.0232 1.635 0.813 0.68 0.972 -0.0864 0.0921 0.348 0.4581 0.917 0.766 1.1 PRS_PLINK_0.00398107170553497 FALSE 741 Symptoms and disorders of the joints Both 1625 3231 14 musculoskeletal darkolivegreen 3231, 1625 807, 402 808, 411 807, 406 808, 406 0.00387 0.0321 0.904 0.04376 1 0.943 1.07 -0.0139 0.0891 0.876 0.05769 0.986 0.828 1.17 -0.0141 0.0909 0.877 0.05705 0.986 0.825 1.18 -0.00319 0.0923 0.972 0.01216 0.997 0.832 1.19 PRS_PLINK_0.00398107170553497 FALSE 741.1 Ankylosis of joint Both 26 168 14 musculoskeletal darkolivegreen 168, 26 42, 9 42, 5 42, 4 42, 8 -0.067 0.204 0.743 0.1291 0.935 0.627 1.4 -0.458 0.601 0.446 0.3508 0.632 0.195 2.05 -1.35 0.756 0.0745 1.128 0.26 0.059 1.14 -0.0548 0.537 0.919 0.0368 0.947 0.33 2.71 PRS_PLINK_0.00398107170553497 TRUE 741.2 Stiffness of joint Both 258 1286 14 musculoskeletal darkolivegreen 1286, 258 322, 62 321, 63 321, 74 322, 59 0.000745 0.0693 0.991 0.003739 1 0.874 1.15 0.0527 0.198 0.79 0.1022 1.05 0.715 1.55 0.203 0.196 0.301 0.5213 1.22 0.834 1.8 -0.00468 0.206 0.982 0.007954 0.995 0.665 1.49 PRS_PLINK_0.00398107170553497 FALSE 741.3 Difficulty in walking Both 411 1963 14 musculoskeletal darkolivegreen 1963, 411 490, 102 491, 115 490, 90 491, 104 0.00523 0.0554 0.925 0.03398 1.01 0.902 1.12 0.0925 0.154 0.547 0.2618 1.1 0.812 1.48 -0.134 0.164 0.414 0.3834 0.874 0.634 1.21 -0.0656 0.162 0.686 0.1636 0.937 0.681 1.29 PRS_PLINK_0.00398107170553497 FALSE 741.4 Joint effusions Both 576 2296 14 musculoskeletal darkolivegreen 2296, 576 573, 136 574, 143 574, 137 574, 160 0.0204 0.048 0.671 0.1735 1.02 0.929 1.12 -0.00427 0.136 0.975 0.01098 0.996 0.762 1.3 -0.0236 0.14 0.866 0.06233 0.977 0.742 1.29 0.16 0.138 0.247 0.6073 1.17 0.895 1.54 PRS_PLINK_0.00398107170553497 FALSE 741.5 Hemarthrosis Both 18 95 14 musculoskeletal darkolivegreen 95, 18 24, 4 24, 2 23, 6 24, 6 -0.14 0.26 0.592 0.2277 0.87 0.522 1.45 -0.553 0.888 0.533 0.2729 0.575 0.101 3.28 0.134 0.717 0.852 0.06947 1.14 0.281 4.66 -0.0352 0.713 0.961 0.01743 0.965 0.239 3.9 PRS_PLINK_0.00398107170553497 TRUE 741.6 Villonodular synovitis Both 18 60 14 musculoskeletal darkolivegreen 60, 18 15, 8 15, 3 15, 6 15, 1 -0.48 0.318 0.131 0.8823 0.619 0.332 1.15 -1.79 1.08 0.097 1.013 0.167 0.0202 1.38 -0.845 0.893 0.344 0.4636 0.43 0.0746 2.47 -1.8 1.11 0.104 0.9828 0.165 0.0188 1.45 PRS_PLINK_0.00398107170553497 TRUE 742 Derangement of joint, non-traumatic Both 857 3098 14 musculoskeletal darkolivegreen 3098, 857 774, 228 774, 219 774, 222 775, 188 -0.043 0.0398 0.281 0.552 0.958 0.886 1.04 -0.0511 0.11 0.641 0.1933 0.95 0.766 1.18 -0.0431 0.111 0.698 0.1563 0.958 0.771 1.19 -0.2 0.116 0.0853 1.069 0.818 0.652 1.03 PRS_PLINK_0.00398107170553497 FALSE 742.1 Loose body in joint Both 21 116 14 musculoskeletal darkolivegreen 116, 21 29, 6 29, 2 29, 5 29, 8 0.154 0.249 0.536 0.271 1.17 0.716 1.9 -0.864 0.822 0.293 0.5334 0.421 0.0842 2.11 0.243 0.791 0.758 0.1201 1.28 0.271 6.01 0.117 0.665 0.86 0.06553 1.12 0.305 4.14 PRS_PLINK_0.00398107170553497 TRUE 742.2 Pathological, developmental or recurrent dislocation Both 25 180 14 musculoskeletal darkolivegreen 180, 25 45, 6 45, 5 45, 8 45, 6 0.0451 0.195 0.817 0.08761 1.05 0.714 1.53 0.194 0.672 0.773 0.1118 1.21 0.325 4.53 0.687 0.616 0.265 0.5768 1.99 0.594 6.65 0.124 0.602 0.836 0.07762 1.13 0.348 3.68 PRS_PLINK_0.00398107170553497 TRUE 742.8 Articular cartilage disorder Both 34 200 14 musculoskeletal darkolivegreen 200, 34 50, 7 50, 9 50, 6 50, 12 0.253 0.194 0.192 0.7172 1.29 0.881 1.88 0.248 0.542 0.647 0.1891 1.28 0.443 3.71 -0.164 0.601 0.784 0.1055 0.848 0.261 2.75 0.916 0.577 0.112 0.9507 2.5 0.807 7.74 PRS_PLINK_0.00398107170553497 TRUE 742.9 Other derangement of joint Both 823 3067 14 musculoskeletal darkolivegreen 3067, 823 766, 217 767, 216 766, 212 767, 178 -0.0471 0.0406 0.246 0.6088 0.954 0.881 1.03 -0.02 0.111 0.857 0.06713 0.98 0.789 1.22 -0.0489 0.113 0.666 0.1765 0.952 0.763 1.19 -0.204 0.119 0.086 1.065 0.815 0.646 1.03 PRS_PLINK_0.00398107170553497 FALSE 743 Osteoporosis, osteopenia and pathological fracture Both 2051 3098 14 musculoskeletal darkolivegreen 3098, 2051 775, 510 774, 555 774, 496 775, 489 -0.0189 0.0336 0.573 0.2419 0.981 0.919 1.05 0.0892 0.0923 0.334 0.4764 1.09 0.912 1.31 0.0101 0.0952 0.916 0.03817 1.01 0.838 1.22 0.015 0.0959 0.876 0.0576 1.02 0.841 1.22 PRS_PLINK_0.00398107170553497 FALSE 743.1 Osteoporosis Both 984 1904 14 musculoskeletal darkolivegreen 1904, 984 476, 241 476, 266 476, 226 476, 250 -0.0462 0.0462 0.316 0.4998 0.955 0.872 1.05 0.022 0.129 0.864 0.06334 1.02 0.794 1.32 -0.155 0.134 0.248 0.6052 0.856 0.658 1.11 -0.00778 0.131 0.953 0.02102 0.992 0.767 1.28 PRS_PLINK_0.00398107170553497 FALSE 743.11 Osteoporosis NOS Both 973 1895 14 musculoskeletal darkolivegreen 1895, 973 474, 238 474, 265 473, 220 474, 249 -0.0443 0.0463 0.339 0.4697 0.957 0.874 1.05 0.0354 0.129 0.784 0.1058 1.04 0.805 1.33 -0.168 0.136 0.217 0.663 0.846 0.648 1.1 0.00097 0.132 0.994 0.002558 1 0.773 1.3 PRS_PLINK_0.00398107170553497 FALSE 743.12 Senile osteoporosis Both 305 555 14 musculoskeletal darkolivegreen 555, 305 139, 83 139, 74 138, 72 139, 76 -0.0759 0.077 0.325 0.4887 0.927 0.797 1.08 -0.187 0.214 0.382 0.4175 0.83 0.546 1.26 -0.268 0.221 0.225 0.6482 0.765 0.496 1.18 -0.237 0.226 0.294 0.5314 0.789 0.507 1.23 PRS_PLINK_0.00398107170553497 FALSE 743.13 Other specified osteoporosis Both 102 315 14 musculoskeletal darkolivegreen 315, 102 79, 30 79, 24 78, 25 79, 23 -0.151 0.119 0.204 0.6913 0.86 0.682 1.09 -0.146 0.329 0.657 0.1822 0.864 0.453 1.65 -0.18 0.33 0.586 0.2322 0.836 0.438 1.59 -0.259 0.338 0.443 0.3534 0.772 0.398 1.5 PRS_PLINK_0.00398107170553497 FALSE 743.2 Pathologic fracture Both 253 898 14 musculoskeletal darkolivegreen 898, 253 225, 67 224, 69 224, 62 225, 54 -0.0833 0.0735 0.257 0.5899 0.92 0.797 1.06 -0.0209 0.202 0.918 0.03727 0.979 0.659 1.46 -0.163 0.208 0.435 0.3617 0.85 0.565 1.28 -0.28 0.218 0.2 0.6982 0.756 0.493 1.16 PRS_PLINK_0.00398107170553497 FALSE 743.21 Pathologic fracture of vertebrae Both 97 349 14 musculoskeletal darkolivegreen 349, 97 88, 25 87, 23 87, 22 87, 26 -0.00383 0.119 0.974 0.01129 0.996 0.789 1.26 -0.193 0.345 0.575 0.24 0.824 0.419 1.62 -0.312 0.344 0.364 0.4384 0.732 0.373 1.44 0.0218 0.342 0.949 0.02267 1.02 0.523 2 PRS_PLINK_0.00398107170553497 FALSE 743.22 Pathologic fracture of femur Both 31 114 14 musculoskeletal darkolivegreen 114, 31 29, 10 28, 3 28, 11 29, 7 -0.14 0.245 0.569 0.2449 0.87 0.538 1.41 -1.03 0.684 0.134 0.874 0.359 0.0939 1.37 0.179 0.537 0.739 0.1314 1.2 0.417 3.43 -0.621 0.663 0.349 0.4577 0.537 0.147 1.97 PRS_PLINK_0.00398107170553497 TRUE 743.4 Stress fracture Both 119 483 14 musculoskeletal darkolivegreen 483, 119 121, 35 121, 30 120, 26 121, 28 -0.0873 0.107 0.416 0.3808 0.916 0.742 1.13 -0.102 0.286 0.721 0.1418 0.903 0.516 1.58 -0.154 0.307 0.615 0.2108 0.857 0.47 1.56 -0.142 0.299 0.636 0.1966 0.868 0.483 1.56 PRS_PLINK_0.00398107170553497 FALSE 743.9 Osteopenia or other disorder of bone and cartilage Both 1705 2966 14 musculoskeletal darkolivegreen 2966, 1705 742, 421 741, 454 741, 411 742, 419 -0.0117 0.0357 0.743 0.1293 0.988 0.921 1.06 0.0913 0.0986 0.355 0.4503 1.1 0.903 1.33 0.0138 0.102 0.893 0.04912 1.01 0.829 1.24 0.0752 0.101 0.458 0.3393 1.08 0.884 1.31 PRS_PLINK_0.00398107170553497 FALSE 745 Pain in joint Both 3658 1574 14 musculoskeletal darkolivegreen 1574, 3658 394, 847 393, 1025 393, 906 394, 879 0.0198 0.0318 0.533 0.273 1.02 0.958 1.09 0.191 0.0888 0.0317 1.498 1.21 1.02 1.44 0.0919 0.0911 0.313 0.5046 1.1 0.917 1.31 0.0949 0.0926 0.306 0.5147 1.1 0.917 1.32 PRS_PLINK_0.00398107170553497 FALSE 747 Cardiac and circulatory congenital anomalies Both 347 2270 15 congenital anomalies mediumspringgreen 2270, 347 567, 90 567, 86 567, 90 568, 81 -0.0353 0.0604 0.558 0.253 0.965 0.858 1.09 -0.0744 0.163 0.648 0.1881 0.928 0.674 1.28 -0.0489 0.166 0.768 0.1145 0.952 0.688 1.32 -0.0875 0.171 0.608 0.2158 0.916 0.656 1.28 PRS_PLINK_0.00398107170553497 FALSE 747.1 Cardiac congenital anomalies Both 282 1740 15 congenital anomalies mediumspringgreen 1740, 282 434, 68 435, 73 435, 73 435, 68 -0.0142 0.0678 0.835 0.07857 0.986 0.863 1.13 0.00823 0.184 0.964 0.01583 1.01 0.704 1.44 -0.0387 0.187 0.836 0.07787 0.962 0.667 1.39 -0.00441 0.192 0.982 0.008008 0.996 0.683 1.45 PRS_PLINK_0.00398107170553497 FALSE 747.11 Cardiac shunt/ heart septal defect Both 114 711 15 congenital anomalies mediumspringgreen 711, 114 177, 28 178, 34 177, 24 178, 28 -0.0157 0.106 0.882 0.05434 0.984 0.8 1.21 0.169 0.281 0.549 0.2606 1.18 0.682 2.05 -0.0876 0.305 0.774 0.1111 0.916 0.504 1.67 -0.00785 0.307 0.98 0.008948 0.992 0.544 1.81 PRS_PLINK_0.00398107170553497 FALSE 747.12 Valvular heart disease/ heart chambers Both 115 648 15 congenital anomalies mediumspringgreen 648, 115 162, 23 162, 30 162, 33 162, 29 0.058 0.105 0.579 0.2373 1.06 0.863 1.3 0.18 0.301 0.551 0.2587 1.2 0.663 2.16 0.179 0.302 0.554 0.2567 1.2 0.661 2.16 0.13 0.309 0.675 0.1709 1.14 0.621 2.09 PRS_PLINK_0.00398107170553497 FALSE 747.13 Congenital anomalies of great vessels Both 59 366 15 congenital anomalies mediumspringgreen 366, 59 92, 12 91, 13 91, 20 92, 14 0.114 0.147 0.436 0.3606 1.12 0.841 1.49 0.104 0.423 0.805 0.094 1.11 0.484 2.54 0.328 0.413 0.427 0.37 1.39 0.618 3.12 0.192 0.441 0.663 0.1784 1.21 0.51 2.88 PRS_PLINK_0.00398107170553497 FALSE 747.2 Congenital anomalies of peripheral vascular system Both 64 529 15 congenital anomalies mediumspringgreen 529, 64 133, 22 132, 13 132, 14 132, 15 -0.0875 0.138 0.526 0.2793 0.916 0.699 1.2 -0.46 0.366 0.209 0.6806 0.631 0.308 1.29 -0.42 0.359 0.242 0.6155 0.657 0.325 1.33 -0.268 0.362 0.46 0.3369 0.765 0.376 1.56 PRS_PLINK_0.00398107170553497 FALSE 748 Anomalies of respiratory system, congenital Both 15 124 15 congenital anomalies mediumspringgreen 124, 15 31, 4 31, 4 31, 3 31, 4 -0.267 0.309 0.388 0.4112 0.766 0.418 1.4 -0.105 0.735 0.887 0.05231 0.9 0.213 3.8 -0.162 0.776 0.835 0.07852 0.85 0.186 3.9 -0.552 0.8 0.49 0.3098 0.576 0.12 2.76 PRS_PLINK_0.00398107170553497 TRUE 749 Congenital anomalies of face and neck Both 60 529 15 congenital anomalies mediumspringgreen 529, 60 133, 14 132, 17 132, 14 132, 15 -0.0785 0.135 0.562 0.2501 0.924 0.709 1.21 -0.0148 0.38 0.969 0.01375 0.985 0.468 2.07 -0.111 0.395 0.779 0.1084 0.895 0.413 1.94 -0.186 0.395 0.638 0.1952 0.83 0.383 1.8 PRS_PLINK_0.00398107170553497 FALSE 749.1 Cleft palate Both 1 59 15 congenital anomalies mediumspringgreen 59, 1 15, 0 15, 0 14, 0 15, 1 0.266 0.728 0.715 0.1458 1.3 0.313 5.43 0.354 1.25 0.777 0.1095 1.43 0.123 16.6 0.147 1.43 0.918 0.03722 1.16 0.0707 19 0.807 1.45 0.578 0.2384 2.24 0.131 38.3 PRS_PLINK_0.00398107170553497 TRUE 749.2 Congenital anomalies of skull and face bones Both 10 88 15 congenital anomalies mediumspringgreen 88, 10 22, 2 22, 3 22, 2 22, 3 -0.0605 0.329 0.854 0.06858 0.941 0.494 1.79 0.181 0.847 0.831 0.08066 1.2 0.228 6.3 -0.391 0.936 0.676 0.17 0.676 0.108 4.24 -0.7 1.03 0.498 0.3032 0.496 0.0657 3.75 PRS_PLINK_0.00398107170553497 TRUE 750 Digestive congenital anomalies Both 188 1087 15 congenital anomalies mediumspringgreen 1087, 188 271, 48 272, 47 271, 43 272, 50 0.00916 0.0806 0.91 0.04118 1.01 0.862 1.18 -0.122 0.226 0.589 0.2301 0.885 0.569 1.38 -0.115 0.232 0.619 0.2081 0.891 0.566 1.4 -0.0181 0.226 0.936 0.02872 0.982 0.631 1.53 PRS_PLINK_0.00398107170553497 FALSE 750.1 Upper gastrointestinal congenital anomalies Both 58 426 15 congenital anomalies mediumspringgreen 426, 58 107, 11 106, 14 106, 19 107, 14 0.0966 0.144 0.503 0.298 1.1 0.83 1.46 0.0737 0.418 0.86 0.0654 1.08 0.474 2.44 0.581 0.403 0.15 0.8241 1.79 0.811 3.94 0.325 0.436 0.456 0.3409 1.38 0.589 3.25 PRS_PLINK_0.00398107170553497 FALSE 750.11 Esophageal atresia/tracheoesophageal fistula Both 25 147 15 congenital anomalies mediumspringgreen 147, 25 37, 8 37, 4 36, 8 37, 5 -0.117 0.229 0.609 0.2155 0.89 0.568 1.39 -0.703 0.645 0.276 0.5591 0.495 0.14 1.75 0.159 0.624 0.799 0.09751 1.17 0.345 3.98 -0.539 0.658 0.413 0.3842 0.584 0.161 2.12 PRS_PLINK_0.00398107170553497 TRUE 750.13 Congenital anomalies of mouth/tongue Both 13 88 15 congenital anomalies mediumspringgreen 88, 13 22, 0 22, 4 22, 5 22, 4 0.613 0.372 0.0993 1.003 1.85 0.89 3.83 1.42 1.33 0.288 0.5413 4.13 0.302 56.5 10.5 5.01 0.0368 1.434 34900 1.9 6.39e+08 1.24 1.27 0.327 0.4849 3.47 0.288 41.9 PRS_PLINK_0.00398107170553497 TRUE 750.14 Congenital anomalies of esophagus Both 26 163 15 congenital anomalies mediumspringgreen 163, 26 41, 7 41, 6 40, 8 41, 5 -0.24 0.223 0.282 0.55 0.787 0.509 1.22 -0.302 0.617 0.624 0.2046 0.739 0.221 2.48 0.0234 0.593 0.969 0.01389 1.02 0.32 3.27 -0.443 0.68 0.515 0.2882 0.642 0.169 2.44 PRS_PLINK_0.00398107170553497 TRUE 750.15 Congenital anomalies of stomach Both 11 81 15 congenital anomalies mediumspringgreen 81, 11 21, 2 20, 3 20, 3 20, 3 0.00517 0.34 0.988 0.00531 1.01 0.516 1.96 0.202 0.96 0.833 0.07923 1.22 0.186 8.04 0.462 0.926 0.617 0.2094 1.59 0.259 9.75 0.355 0.919 0.699 0.1554 1.43 0.236 8.63 PRS_PLINK_0.00398107170553497 TRUE 750.2 Lower gastrointestinal congenital anomalies Both 133 662 15 congenital anomalies mediumspringgreen 662, 133 166, 38 165, 35 165, 23 166, 37 -0.0375 0.101 0.712 0.1478 0.963 0.79 1.17 -0.194 0.265 0.464 0.3336 0.823 0.49 1.38 -0.515 0.288 0.0733 1.135 0.597 0.34 1.05 -0.0401 0.265 0.879 0.05578 0.961 0.572 1.61 PRS_PLINK_0.00398107170553497 FALSE 750.21 Congenital anomalies of intestine Both 97 401 15 congenital anomalies mediumspringgreen 401, 97 100, 31 100, 26 100, 17 100, 23 -0.129 0.113 0.254 0.596 0.879 0.705 1.1 -0.25 0.305 0.413 0.3846 0.779 0.429 1.42 -0.601 0.336 0.0736 1.133 0.548 0.284 1.06 -0.289 0.317 0.363 0.4403 0.749 0.402 1.4 PRS_PLINK_0.00398107170553497 FALSE 750.22 Congenital anomaly of gallbladder, bile ducts, liver, pancreas Both 40 265 15 congenital anomalies mediumspringgreen 265, 40 67, 9 66, 10 66, 9 66, 12 0.0771 0.18 0.668 0.1755 1.08 0.76 1.54 -0.0101 0.519 0.985 0.006775 0.99 0.358 2.74 -0.145 0.493 0.768 0.1145 0.865 0.329 2.27 0.0979 0.487 0.841 0.07537 1.1 0.425 2.86 PRS_PLINK_0.00398107170553497 TRUE 751 Genitourinary congenital anomalies Both 297 2129 15 congenital anomalies mediumspringgreen 2129, 297 532, 76 532, 76 532, 75 532, 70 -0.0267 0.0644 0.679 0.1681 0.974 0.858 1.1 0.0089 0.174 0.959 0.01812 1.01 0.718 1.42 0.0207 0.176 0.907 0.04256 1.02 0.722 1.44 -0.061 0.182 0.737 0.1326 0.941 0.659 1.34 PRS_PLINK_0.00398107170553497 FALSE 751.1 Congenital anomalies of genital organs Both 109 670 15 congenital anomalies mediumspringgreen 670, 109 168, 28 167, 28 167, 26 168, 27 -0.00913 0.108 0.933 0.03023 0.991 0.802 1.22 -0.0279 0.285 0.922 0.03526 0.972 0.556 1.7 -0.0646 0.295 0.827 0.08267 0.937 0.526 1.67 -0.0896 0.298 0.764 0.1172 0.914 0.51 1.64 PRS_PLINK_0.00398107170553497 FALSE 751.11 Congenital anomalies of female genital organs Female 96 589 15 congenital anomalies mediumspringgreen 589, 96 148, 24 147, 23 147, 23 147, 26 0.0352 0.114 0.757 0.1208 1.04 0.829 1.29 0.00455 0.311 0.988 0.005105 1 0.546 1.85 -0.0668 0.31 0.829 0.08126 0.935 0.51 1.72 -0.0398 0.309 0.898 0.0469 0.961 0.524 1.76 PRS_PLINK_0.00398107170553497 FALSE 751.12 Congenital anomalies of male genital organs Male 8 57 15 congenital anomalies mediumspringgreen 57, 8 15, 5 14, 0 14, 2 14, 1 -0.327 0.397 0.41 0.3872 0.721 0.331 1.57 -1.89 1.36 0.165 0.7828 0.152 0.0106 2.17 -0.308 1 0.758 0.1204 0.735 0.103 5.22 -0.888 1 0.376 0.4247 0.411 0.0575 2.94 PRS_PLINK_0.00398107170553497 TRUE 751.2 Congenital anomalies of urinary system Both 189 1406 15 congenital anomalies mediumspringgreen 1406, 189 351, 50 351, 47 351, 50 352, 42 -0.0316 0.0801 0.693 0.159 0.969 0.828 1.13 -0.00266 0.218 0.99 0.004238 0.997 0.65 1.53 0.0795 0.219 0.716 0.1449 1.08 0.705 1.66 -0.141 0.229 0.539 0.2681 0.869 0.554 1.36 PRS_PLINK_0.00398107170553497 FALSE 751.21 Cystic kidney disease Both 144 1018 15 congenital anomalies mediumspringgreen 1018, 144 254, 34 254, 32 254, 39 255, 39 0.0408 0.0928 0.661 0.1801 1.04 0.868 1.25 -0.0648 0.263 0.805 0.094 0.937 0.56 1.57 0.219 0.257 0.395 0.403 1.24 0.751 2.06 0.187 0.26 0.472 0.3259 1.21 0.724 2.01 PRS_PLINK_0.00398107170553497 FALSE 751.22 Other specified congenital anomalies of kidney Both 31 299 15 congenital anomalies mediumspringgreen 299, 31 75, 9 75, 8 74, 11 75, 3 -0.196 0.198 0.322 0.4916 0.822 0.558 1.21 -0.0162 0.499 0.974 0.01135 0.984 0.37 2.62 0.213 0.496 0.668 0.1753 1.24 0.468 3.27 -1.18 0.634 0.0639 1.194 0.309 0.0891 1.07 PRS_PLINK_0.00398107170553497 TRUE 751.3 Obstructive genitourinary defect Both 17 181 15 congenital anomalies mediumspringgreen 181, 17 46, 4 45, 5 45, 3 45, 5 -0.00637 0.247 0.979 0.009021 0.994 0.612 1.61 -0.219 0.711 0.758 0.1201 0.804 0.2 3.24 -0.207 0.774 0.789 0.1029 0.813 0.178 3.7 -0.0701 0.706 0.921 0.03575 0.932 0.234 3.72 PRS_PLINK_0.00398107170553497 TRUE 752 Nervous system congenital anomalies Both 170 1323 15 congenital anomalies mediumspringgreen 1323, 170 330, 48 331, 47 330, 45 331, 30 -0.13 0.0818 0.112 0.9519 0.878 0.748 1.03 -0.00927 0.221 0.967 0.01474 0.991 0.642 1.53 -0.0519 0.225 0.818 0.08745 0.949 0.611 1.48 -0.525 0.253 0.0382 1.418 0.591 0.36 0.972 PRS_PLINK_0.00398107170553497 FALSE 752.1 Neural tube defects Both 140 1086 15 congenital anomalies mediumspringgreen 1086, 140 272, 40 271, 39 271, 37 272, 24 -0.148 0.0924 0.11 0.9578 0.863 0.72 1.03 0.0046 0.245 0.985 0.006558 1 0.622 1.62 -0.0192 0.25 0.939 0.02739 0.981 0.601 1.6 -0.495 0.281 0.0779 1.108 0.61 0.352 1.06 PRS_PLINK_0.00398107170553497 FALSE 752.11 Spina bifida Both 20 184 15 congenital anomalies mediumspringgreen 184, 20 46, 5 46, 2 46, 4 46, 9 0.468 0.244 0.0557 1.254 1.6 0.989 2.58 -1.07 0.946 0.259 0.5871 0.344 0.0538 2.19 0.221 0.76 0.771 0.1129 1.25 0.281 5.53 1.12 0.626 0.0748 1.126 3.05 0.894 10.4 PRS_PLINK_0.00398107170553497 TRUE 752.2 Other specified congenital anomalies of nervous system Both 25 237 15 congenital anomalies mediumspringgreen 237, 25 59, 2 59, 9 59, 7 59, 7 0.189 0.19 0.32 0.495 1.21 0.832 1.75 1.29 0.678 0.0565 1.248 3.65 0.965 13.8 0.909 0.695 0.191 0.7197 2.48 0.636 9.69 1 0.696 0.15 0.8228 2.72 0.695 10.7 PRS_PLINK_0.00398107170553497 TRUE 753 Congenital anomalies of the eye Both 43 268 15 congenital anomalies mediumspringgreen 268, 43 67, 8 67, 11 67, 8 67, 16 0.155 0.167 0.353 0.4522 1.17 0.842 1.62 0.217 0.482 0.653 0.1853 1.24 0.483 3.19 0.101 0.539 0.852 0.06973 1.11 0.385 3.18 0.68 0.464 0.142 0.8465 1.97 0.796 4.9 PRS_PLINK_0.00398107170553497 TRUE 753.1 Congenital cataract and lens anomalies Both 14 76 15 congenital anomalies mediumspringgreen 76, 14 19, 5 19, 3 19, 3 19, 3 -0.315 0.284 0.266 0.5749 0.73 0.418 1.27 -0.305 0.865 0.724 0.14 0.737 0.135 4.02 -0.00543 0.87 0.995 0.002169 0.995 0.181 5.47 -0.242 0.79 0.759 0.1197 0.785 0.167 3.69 PRS_PLINK_0.00398107170553497 TRUE 753.2 Congenital anomalies of posterior segment of eye Both 12 79 15 congenital anomalies mediumspringgreen 79, 12 20, 3 20, 2 19, 1 20, 6 0.342 0.325 0.293 0.5337 1.41 0.745 2.66 0.0588 0.892 0.947 0.02346 1.06 0.185 6.09 -0.00537 1.18 0.996 0.001584 0.995 0.0992 9.97 0.285 0.766 0.71 0.1489 1.33 0.296 5.97 PRS_PLINK_0.00398107170553497 TRUE 754 Congenital musculoskeletal deformities of spine Both 212 1425 15 congenital anomalies mediumspringgreen 1425, 212 357, 58 356, 59 356, 57 356, 38 -0.155 0.0764 0.0431 1.365 0.857 0.738 0.995 0.0235 0.203 0.908 0.04214 1.02 0.688 1.52 -0.0663 0.207 0.749 0.1258 0.936 0.624 1.4 -0.541 0.232 0.0194 1.712 0.582 0.37 0.916 PRS_PLINK_0.00398107170553497 FALSE 754.1 Lumbosacral spondylolysis, congenital Both 37 172 15 congenital anomalies mediumspringgreen 172, 37 43, 7 43, 6 43, 16 43, 8 0.321 0.21 0.126 0.8986 1.38 0.914 2.08 0.155 0.6 0.796 0.09893 1.17 0.36 3.78 0.915 0.523 0.0802 1.096 2.5 0.896 6.95 0.272 0.66 0.68 0.1674 1.31 0.36 4.78 PRS_PLINK_0.00398107170553497 TRUE 754.2 Spondylolisthesis, congenital Both 92 697 15 congenital anomalies mediumspringgreen 697, 92 175, 23 174, 27 174, 24 174, 18 -0.1 0.114 0.378 0.4221 0.905 0.724 1.13 0.213 0.304 0.483 0.3161 1.24 0.682 2.25 0.00828 0.317 0.979 0.009131 1.01 0.541 1.88 -0.337 0.341 0.323 0.4907 0.714 0.365 1.39 PRS_PLINK_0.00398107170553497 FALSE 755 Congenital anomalies of limbs Both 144 854 15 congenital anomalies mediumspringgreen 854, 144 213, 34 213, 34 213, 31 214, 45 0.0648 0.092 0.481 0.3176 1.07 0.891 1.28 -0.0548 0.261 0.834 0.07901 0.947 0.568 1.58 -0.0497 0.272 0.855 0.06792 0.952 0.558 1.62 0.284 0.252 0.26 0.5843 1.33 0.81 2.18 PRS_PLINK_0.00398107170553497 FALSE 755.1 Congenital deformities of feet Both 78 426 15 congenital anomalies mediumspringgreen 426, 78 107, 13 106, 17 106, 23 107, 25 0.254 0.127 0.0456 1.341 1.29 1 1.65 0.12 0.384 0.755 0.1222 1.13 0.531 2.39 0.643 0.38 0.0908 1.042 1.9 0.903 4.01 0.648 0.374 0.0834 1.079 1.91 0.918 3.98 PRS_PLINK_0.00398107170553497 FALSE 755.4 Congenital anomalies of upper limb, including shoulder girdle Both 14 78 15 congenital anomalies mediumspringgreen 78, 14 19, 3 19, 3 19, 3 20, 5 0.228 0.263 0.387 0.4121 1.26 0.749 2.1 0.8 1.07 0.457 0.3402 2.22 0.271 18.3 0.00315 0.905 0.997 0.001209 1 0.17 5.91 0.0552 0.82 0.946 0.02393 1.06 0.212 5.27 PRS_PLINK_0.00398107170553497 TRUE 755.6 Other congenital anomalies of lower limb, including pelvic girdle Both 53 345 15 congenital anomalies mediumspringgreen 345, 53 87, 19 86, 15 86, 7 86, 12 -0.326 0.16 0.0421 1.376 0.722 0.527 0.988 -0.296 0.389 0.447 0.35 0.744 0.347 1.59 -0.9 0.476 0.0588 1.231 0.407 0.16 1.03 -0.393 0.408 0.336 0.4739 0.675 0.304 1.5 PRS_PLINK_0.00398107170553497 FALSE 755.61 Congenital hip dysplasia and deformity Both 31 214 15 congenital anomalies mediumspringgreen 214, 31 54, 13 53, 8 53, 5 54, 5 -0.385 0.207 0.0623 1.205 0.68 0.454 1.02 -0.626 0.514 0.223 0.6519 0.535 0.195 1.46 -0.748 0.577 0.195 0.7104 0.473 0.153 1.47 -0.828 0.524 0.114 0.9428 0.437 0.156 1.22 PRS_PLINK_0.00398107170553497 TRUE 756 Other congenital musculoskeletal anomalies Both 197 1459 15 congenital anomalies mediumspringgreen 1459, 197 365, 55 365, 48 364, 44 365, 50 -0.0503 0.0776 0.517 0.2865 0.951 0.817 1.11 -0.162 0.211 0.442 0.355 0.85 0.563 1.29 -0.199 0.218 0.361 0.4427 0.819 0.535 1.26 -0.0351 0.214 0.869 0.06084 0.965 0.635 1.47 PRS_PLINK_0.00398107170553497 FALSE 756.1 Congenital anomalies of abdominal wall; diaphram Both 5 69 15 congenital anomalies mediumspringgreen 69, 5 18, 0 17, 2 17, 3 17, 0 -0.177 0.41 0.666 0.1768 0.838 0.375 1.87 1.62 1.3 0.213 0.6711 5.06 0.394 65 1.16 1.26 0.354 0.4507 3.2 0.273 37.5 0.113 1.38 0.934 0.02949 1.12 0.0755 16.6 PRS_PLINK_0.00398107170553497 TRUE 756.2 Pectus and other congenital anomalies of ribs/sternum Both 5 46 15 congenital anomalies mediumspringgreen 46, 5 12, 1 11, 1 11, 0 12, 3 0.015 0.496 0.976 0.0106 1.02 0.384 2.68 -0.538 1.38 0.696 0.1573 0.584 0.0392 8.7 -0.631 1.39 0.649 0.1874 0.532 0.0349 8.1 0.121 1.3 0.926 0.03354 1.13 0.0889 14.3 PRS_PLINK_0.00398107170553497 TRUE 756.3 Congenital anomalies of muscle, tendon, fascia, and connective tissue Both 51 352 15 congenital anomalies mediumspringgreen 352, 51 88, 13 88, 12 88, 9 88, 17 0.066 0.155 0.671 0.1731 1.07 0.788 1.45 -0.0344 0.424 0.935 0.02902 0.966 0.421 2.22 -0.322 0.443 0.467 0.3304 0.725 0.304 1.73 0.281 0.402 0.486 0.3137 1.32 0.602 2.91 PRS_PLINK_0.00398107170553497 FALSE 756.5 Congenital osteodystrophies Both 146 1113 15 congenital anomalies mediumspringgreen 1113, 146 279, 44 278, 35 278, 29 278, 38 -0.00712 0.0927 0.939 0.02743 0.993 0.828 1.19 -0.249 0.244 0.307 0.5135 0.78 0.484 1.26 -0.379 0.256 0.138 0.8588 0.684 0.414 1.13 -0.103 0.244 0.672 0.1729 0.902 0.559 1.45 PRS_PLINK_0.00398107170553497 FALSE 757 Congenital anomalies of the integument Both 57 519 15 congenital anomalies mediumspringgreen 519, 57 130, 20 130, 11 129, 13 130, 13 -0.111 0.139 0.425 0.3718 0.895 0.681 1.18 -0.486 0.387 0.209 0.6793 0.615 0.288 1.31 -0.221 0.38 0.56 0.2517 0.801 0.38 1.69 -0.388 0.378 0.305 0.5156 0.679 0.324 1.42 PRS_PLINK_0.00398107170553497 FALSE 758 Chromosomal anomalies and genetic disorders Both 29 227 15 congenital anomalies mediumspringgreen 227, 29 57, 5 57, 10 56, 8 57, 6 0.0238 0.199 0.905 0.0435 1.02 0.694 1.51 0.968 0.631 0.125 0.9041 2.63 0.765 9.07 0.375 0.563 0.506 0.296 1.45 0.482 4.38 -0.0775 0.638 0.903 0.0442 0.925 0.265 3.23 PRS_PLINK_0.00398107170553497 TRUE 758.1 Chromosomal anomalies Both 25 171 15 congenital anomalies mediumspringgreen 171, 25 43, 5 43, 9 42, 7 43, 4 -0.0649 0.219 0.767 0.1151 0.937 0.61 1.44 0.527 0.657 0.422 0.3743 1.69 0.467 6.14 0.284 0.631 0.653 0.1851 1.33 0.386 4.57 -1.21 0.823 0.142 0.8471 0.299 0.0595 1.5 PRS_PLINK_0.00398107170553497 TRUE 759 Other and unspecified congenital anomalies Both 93 651 15 congenital anomalies mediumspringgreen 651, 93 163, 26 163, 22 162, 19 163, 26 0.000167 0.119 0.999 0.0004874 1 0.793 1.26 -0.298 0.31 0.336 0.4734 0.742 0.404 1.36 -0.396 0.325 0.223 0.6516 0.673 0.356 1.27 -0.104 0.307 0.734 0.1344 0.901 0.493 1.65 PRS_PLINK_0.00398107170553497 FALSE 759.1 Anomalies of endocrine glands, congenital Both 15 101 15 congenital anomalies mediumspringgreen 101, 15 26, 5 25, 3 25, 1 25, 6 -0.166 0.29 0.568 0.2456 0.847 0.48 1.5 -0.00725 0.822 0.993 0.003069 0.993 0.198 4.97 -1.33 0.914 0.145 0.839 0.264 0.044 1.58 0.399 0.787 0.612 0.2134 1.49 0.319 6.97 PRS_PLINK_0.00398107170553497 TRUE 760 Back pain Both 2895 2335 17 symptoms purple 2335, 2895 584, 674 584, 773 583, 778 584, 669 0.0252 0.0294 0.391 0.4083 1.03 0.968 1.09 0.135 0.0819 0.0999 1.001 1.14 0.975 1.34 0.168 0.083 0.0426 1.37 1.18 1.01 1.39 0.00398 0.086 0.963 0.01634 1 0.848 1.19 PRS_PLINK_0.00398107170553497 FALSE 761 Cervicalgia Both 1457 3753 17 symptoms purple 3753, 1457 938, 369 938, 376 938, 368 938, 344 -0.00292 0.0322 0.928 0.0326 0.997 0.936 1.06 0.0256 0.0888 0.773 0.1116 1.03 0.862 1.22 0.0143 0.0901 0.874 0.05858 1.01 0.85 1.21 -0.0541 0.0928 0.56 0.2518 0.947 0.79 1.14 PRS_PLINK_0.00398107170553497 FALSE 763 Thoracic or lumbosacral neuritis or radiculitis, unspecified Both 700 3237 17 symptoms purple 3237, 700 810, 168 809, 200 809, 175 809, 156 -0.0329 0.0435 0.449 0.3479 0.968 0.889 1.05 0.165 0.119 0.163 0.7869 1.18 0.935 1.49 0.000507 0.123 0.997 0.001434 1 0.787 1.27 -0.131 0.128 0.305 0.516 0.877 0.683 1.13 PRS_PLINK_0.00398107170553497 FALSE 764 Sciatica Both 696 3329 17 symptoms purple 3329, 696 833, 165 832, 185 832, 180 832, 165 -0.000661 0.0437 0.988 0.005278 0.999 0.917 1.09 0.11 0.12 0.359 0.4451 1.12 0.883 1.41 0.0297 0.122 0.808 0.09281 1.03 0.811 1.31 -0.0569 0.126 0.651 0.1866 0.945 0.738 1.21 PRS_PLINK_0.00398107170553497 FALSE 765 Cervical radiculitis Both 364 1909 17 symptoms purple 1909, 364 478, 93 477, 77 477, 96 477, 98 0.036 0.0596 0.546 0.263 1.04 0.922 1.17 -0.193 0.169 0.252 0.5991 0.824 0.592 1.15 -0.0145 0.162 0.929 0.03216 0.986 0.718 1.35 0.0198 0.164 0.904 0.04379 1.02 0.74 1.41 PRS_PLINK_0.00398107170553497 FALSE 766 Neuralgia, neuritis, and radiculitis NOS Both 937 3581 17 symptoms purple 3581, 937 896, 214 895, 250 895, 235 895, 237 0.0306 0.0382 0.423 0.3741 1.03 0.957 1.11 0.129 0.107 0.229 0.6409 1.14 0.922 1.4 0.0553 0.108 0.61 0.2146 1.06 0.854 1.31 0.0587 0.11 0.594 0.2264 1.06 0.855 1.32 PRS_PLINK_0.00398107170553497 FALSE 767 Cervicocranial/Cervicobrachial syndrome Both 29 163 17 symptoms purple 163, 29 41, 3 41, 6 40, 15 41, 5 0.226 0.217 0.299 0.5248 1.25 0.819 1.92 0.209 0.686 0.761 0.1188 1.23 0.322 4.72 1.27 0.623 0.0421 1.376 3.55 1.05 12 0.477 0.673 0.479 0.3196 1.61 0.43 6.03 PRS_PLINK_0.00398107170553497 TRUE 769 Nonallopathic lesions NEC Both 315 1557 17 symptoms purple 1557, 315 390, 74 389, 87 389, 81 389, 73 -0.0671 0.0647 0.3 0.5231 0.935 0.824 1.06 0.134 0.176 0.447 0.3495 1.14 0.809 1.62 0.0241 0.18 0.893 0.04894 1.02 0.72 1.46 -0.0746 0.187 0.689 0.1616 0.928 0.644 1.34 PRS_PLINK_0.00398107170553497 FALSE 770 Myalgia and myositis unspecified Both 1172 3764 17 symptoms purple 3764, 1172 940, 303 941, 288 941, 286 941, 295 0.00634 0.0347 0.855 0.06814 1.01 0.94 1.08 -0.0476 0.0955 0.618 0.209 0.953 0.791 1.15 -0.0707 0.0973 0.468 0.3302 0.932 0.77 1.13 0.0145 0.098 0.883 0.05422 1.01 0.837 1.23 PRS_PLINK_0.00398107170553497 FALSE 771 Musculoskeletal symptoms referable to limbs Both 795 3404 17 symptoms purple 3404, 795 851, 215 851, 210 851, 183 851, 186 -0.0266 0.0412 0.518 0.286 0.974 0.898 1.06 -0.0461 0.11 0.676 0.1698 0.955 0.769 1.19 -0.157 0.115 0.174 0.7595 0.855 0.682 1.07 -0.154 0.117 0.186 0.7311 0.857 0.682 1.08 PRS_PLINK_0.00398107170553497 FALSE 771.1 Swelling of limb Both 996 3442 17 symptoms purple 3442, 996 861, 243 860, 264 860, 246 861, 243 0.0172 0.0379 0.65 0.1871 1.02 0.944 1.1 0.071 0.104 0.494 0.3064 1.07 0.876 1.32 -0.00593 0.107 0.956 0.01956 0.994 0.805 1.23 0.0178 0.109 0.871 0.06011 1.02 0.822 1.26 PRS_PLINK_0.00398107170553497 FALSE 771.2 Cramp of limb Both 246 1245 17 symptoms purple 1245, 246 312, 66 311, 65 311, 51 311, 64 -0.0277 0.0755 0.714 0.1466 0.973 0.839 1.13 -0.0233 0.195 0.905 0.04343 0.977 0.667 1.43 -0.293 0.207 0.158 0.8018 0.746 0.497 1.12 -0.018 0.206 0.93 0.03139 0.982 0.656 1.47 PRS_PLINK_0.00398107170553497 FALSE 772 Symptoms of the muscles Both 482 2338 17 symptoms purple 2338, 482 585, 115 584, 126 584, 109 585, 132 0.00777 0.052 0.881 0.05493 1.01 0.91 1.12 0.04 0.143 0.78 0.1079 1.04 0.786 1.38 -0.103 0.149 0.488 0.3115 0.902 0.673 1.21 0.0849 0.146 0.56 0.2518 1.09 0.818 1.45 PRS_PLINK_0.00398107170553497 FALSE 772.1 Muscular wasting and disuse atrophy Both 74 344 17 symptoms purple 344, 74 86, 18 86, 20 86, 14 86, 22 0.0339 0.129 0.793 0.1007 1.03 0.803 1.33 0.109 0.367 0.765 0.1162 1.12 0.544 2.29 -0.381 0.422 0.367 0.4352 0.683 0.299 1.56 0.235 0.359 0.513 0.2901 1.27 0.626 2.56 PRS_PLINK_0.00398107170553497 FALSE 772.2 Spasm of muscle Both 442 2654 17 symptoms purple 2654, 442 663, 114 663, 121 663, 117 664, 90 -0.0693 0.0537 0.197 0.705 0.933 0.84 1.04 0.0505 0.143 0.724 0.1404 1.05 0.795 1.39 -0.00362 0.145 0.98 0.008714 0.996 0.749 1.32 -0.244 0.157 0.12 0.9198 0.784 0.576 1.07 PRS_PLINK_0.00398107170553497 FALSE 772.3 Muscle weakness Both 514 2831 17 symptoms purple 2831, 514 707, 146 708, 117 707, 123 708, 128 -0.0646 0.05 0.196 0.708 0.937 0.85 1.03 -0.237 0.137 0.0828 1.082 0.789 0.603 1.03 -0.195 0.137 0.156 0.8073 0.823 0.629 1.08 -0.122 0.139 0.379 0.4217 0.885 0.675 1.16 PRS_PLINK_0.00398107170553497 FALSE 772.4 Rhabdomyolysis Both 21 121 17 symptoms purple 121, 21 31, 5 30, 10 30, 5 30, 1 -0.338 0.227 0.137 0.8642 0.713 0.457 1.11 0.662 0.634 0.297 0.5271 1.94 0.559 6.72 -0.0627 0.737 0.932 0.03046 0.939 0.221 3.98 -1.35 1.05 0.198 0.7042 0.259 0.0333 2.02 PRS_PLINK_0.00398107170553497 TRUE 772.6 Facial weakness Both 49 478 17 symptoms purple 478, 49 120, 12 119, 11 119, 11 120, 15 0.0331 0.146 0.821 0.08563 1.03 0.776 1.38 -0.0364 0.432 0.933 0.03017 0.964 0.414 2.25 -0.115 0.421 0.784 0.1056 0.891 0.39 2.03 0.0946 0.414 0.819 0.08661 1.1 0.489 2.47 PRS_PLINK_0.00398107170553497 TRUE 780 Hypothermia/Chills Both 78 502 17 symptoms purple 502, 78 126, 15 125, 21 125, 24 126, 18 0.121 0.128 0.346 0.4615 1.13 0.878 1.45 0.376 0.367 0.306 0.5147 1.46 0.709 2.99 0.527 0.35 0.132 0.878 1.69 0.853 3.36 0.309 0.389 0.427 0.3695 1.36 0.636 2.92 PRS_PLINK_0.00398107170553497 FALSE 781 Symptoms involving nervous and musculoskeletal systems Both 506 2894 17 symptoms purple 2894, 506 724, 124 723, 129 723, 109 724, 143 0.0604 0.0501 0.228 0.6417 1.06 0.963 1.17 0.0104 0.137 0.94 0.02698 1.01 0.772 1.32 -0.197 0.145 0.173 0.7616 0.821 0.618 1.09 0.118 0.138 0.392 0.4066 1.13 0.859 1.47 PRS_PLINK_0.00398107170553497 FALSE 781.1 Loss of height Both 41 155 17 symptoms purple 155, 41 39, 10 39, 11 38, 10 39, 10 -0.0452 0.183 0.805 0.09412 0.956 0.667 1.37 0.12 0.509 0.814 0.08926 1.13 0.416 3.06 0.00804 0.528 0.988 0.005311 1.01 0.358 2.84 -0.0632 0.543 0.907 0.04219 0.939 0.324 2.72 PRS_PLINK_0.00398107170553497 TRUE 781.2 Abnormal posture Both 18 65 17 symptoms purple 65, 18 17, 0 16, 7 16, 4 16, 7 0.303 0.283 0.284 0.5461 1.35 0.777 2.36 3.65 1.69 0.0312 1.506 38.5 1.39 1070 1.62 1.19 0.176 0.755 5.03 0.485 52.2 3.06 1.47 0.0371 1.431 21.3 1.2 378 PRS_PLINK_0.00398107170553497 TRUE 782.3 Edema Both 993 3758 17 symptoms purple 3758, 993 939, 238 939, 252 939, 234 940, 269 0.0248 0.0373 0.506 0.2959 1.03 0.953 1.1 0.05 0.104 0.63 0.2003 1.05 0.858 1.29 -0.000203 0.107 0.998 0.0006595 1 0.811 1.23 0.157 0.106 0.138 0.8587 1.17 0.951 1.44 PRS_PLINK_0.00398107170553497 FALSE 782.6 Pallor and flushing Both 246 1277 17 symptoms purple 1277, 246 320, 49 319, 71 319, 52 319, 74 0.0812 0.0726 0.263 0.5798 1.08 0.941 1.25 0.37 0.202 0.0676 1.17 1.45 0.974 2.15 0.0694 0.216 0.748 0.1259 1.07 0.701 1.64 0.418 0.207 0.0428 1.368 1.52 1.01 2.28 PRS_PLINK_0.00398107170553497 FALSE 783 Fever of unknown origin Both 875 4312 17 symptoms purple 4312, 875 1077, 224 1078, 235 1078, 213 1078, 203 -0.0469 0.0381 0.219 0.6602 0.954 0.886 1.03 0.0424 0.104 0.683 0.1654 1.04 0.851 1.28 -0.0626 0.107 0.56 0.2517 0.939 0.761 1.16 -0.111 0.11 0.314 0.5025 0.895 0.721 1.11 PRS_PLINK_0.00398107170553497 FALSE 783.1 Postprocedural fever Both 30 267 17 symptoms purple 267, 30 67, 10 67, 5 66, 7 67, 8 -0.167 0.206 0.417 0.3797 0.846 0.565 1.27 -0.865 0.558 0.121 0.9162 0.421 0.141 1.26 -0.498 0.512 0.33 0.481 0.608 0.223 1.66 -0.342 0.506 0.498 0.3024 0.71 0.264 1.91 PRS_PLINK_0.00398107170553497 TRUE 785 Abdominal pain Both 2843 2389 17 symptoms purple 2389, 2843 598, 709 597, 691 597, 745 597, 697 0.0233 0.029 0.422 0.3748 1.02 0.967 1.08 -0.0211 0.0812 0.794 0.09991 0.979 0.835 1.15 0.0734 0.0814 0.367 0.435 1.08 0.917 1.26 0.0116 0.0831 0.889 0.05129 1.01 0.86 1.19 PRS_PLINK_0.00398107170553497 FALSE 788 Syncope and collapse Both 696 3844 17 symptoms purple 3844, 696 961, 163 961, 161 961, 194 961, 177 0.0542 0.0425 0.202 0.6937 1.06 0.971 1.15 -0.0145 0.121 0.905 0.04339 0.986 0.777 1.25 0.151 0.119 0.203 0.6934 1.16 0.922 1.47 0.0628 0.122 0.607 0.2165 1.06 0.838 1.35 PRS_PLINK_0.00398107170553497 FALSE 789 Nausea and vomiting Both 1625 3592 17 symptoms purple 3592, 1625 898, 438 898, 401 898, 388 898, 397 -0.00957 0.031 0.758 0.1205 0.99 0.932 1.05 -0.0612 0.0854 0.474 0.3244 0.941 0.796 1.11 -0.0783 0.087 0.368 0.434 0.925 0.78 1.1 -0.0192 0.0882 0.828 0.08214 0.981 0.825 1.17 PRS_PLINK_0.00398107170553497 FALSE 789.1 Persistent vomiting Both 105 868 17 symptoms purple 868, 105 217, 26 217, 29 217, 23 217, 27 0.0521 0.105 0.619 0.2085 1.05 0.858 1.29 0.0861 0.28 0.759 0.1198 1.09 0.629 1.89 -0.136 0.296 0.645 0.1904 0.873 0.488 1.56 0.108 0.291 0.71 0.1485 1.11 0.63 1.97 PRS_PLINK_0.00398107170553497 FALSE 790 Nonspecific findings on examination of blood Both 456 2289 17 symptoms purple 2289, 456 573, 106 572, 122 572, 107 572, 121 -0.00177 0.0538 0.974 0.01158 0.998 0.898 1.11 0.177 0.148 0.233 0.6332 1.19 0.893 1.6 0.0306 0.153 0.841 0.07524 1.03 0.765 1.39 0.183 0.153 0.232 0.6344 1.2 0.889 1.62 PRS_PLINK_0.00398107170553497 FALSE 790.1 Elevated sedimentation rate Both 53 265 17 symptoms purple 265, 53 67, 9 66, 14 66, 15 66, 15 0.209 0.152 0.169 0.7724 1.23 0.915 1.66 0.532 0.476 0.263 0.5792 1.7 0.67 4.32 0.605 0.466 0.195 0.7106 1.83 0.734 4.57 0.831 0.483 0.0856 1.068 2.29 0.89 5.92 PRS_PLINK_0.00398107170553497 FALSE 790.6 Other abnormal blood chemistry Both 1484 3576 17 symptoms purple 3576, 1484 893, 349 894, 348 894, 372 894, 415 0.0386 0.0327 0.237 0.6244 1.04 0.975 1.11 -0.0358 0.0929 0.7 0.1548 0.965 0.804 1.16 0.0255 0.0926 0.783 0.1063 1.03 0.856 1.23 0.173 0.0921 0.0601 1.221 1.19 0.993 1.42 PRS_PLINK_0.00398107170553497 FALSE 790.8 Elevated C-reactive protein (CRP) Both 44 317 17 symptoms purple 317, 44 80, 17 79, 10 79, 5 79, 12 -0.167 0.163 0.304 0.5164 0.846 0.615 1.16 -0.632 0.432 0.144 0.8423 0.532 0.228 1.24 -1.12 0.509 0.0275 1.561 0.325 0.12 0.883 -0.351 0.442 0.426 0.3702 0.704 0.296 1.67 PRS_PLINK_0.00398107170553497 TRUE 790.9 Abnormal arterial blood gases Both 26 149 17 symptoms purple 149, 26 38, 3 37, 6 37, 12 37, 5 0.252 0.217 0.247 0.6074 1.29 0.84 1.97 1.43 0.867 0.0995 1.002 4.17 0.763 22.8 1.28 0.686 0.0612 1.214 3.61 0.942 13.8 0.782 0.764 0.306 0.5141 2.19 0.489 9.77 PRS_PLINK_0.00398107170553497 TRUE 791 Gangrene Both 34 303 17 symptoms purple 303, 34 76, 7 76, 10 75, 7 76, 10 0.00796 0.181 0.965 0.0155 1.01 0.707 1.44 0.169 0.501 0.736 0.1331 1.18 0.444 3.16 0.0332 0.553 0.952 0.02132 1.03 0.35 3.05 0.288 0.513 0.575 0.2402 1.33 0.488 3.64 PRS_PLINK_0.00398107170553497 TRUE 792 Abnormal Papanicolaou smear of cervix and cervical HPV Female 818 1941 11 genitourinary black 1941, 818 485, 169 485, 201 485, 237 485, 211 0.0913 0.0429 0.0332 1.479 1.1 1.01 1.19 0.206 0.125 0.0999 1 1.23 0.961 1.57 0.363 0.123 0.00307 2.514 1.44 1.13 1.83 0.218 0.126 0.0836 1.078 1.24 0.971 1.59 PRS_PLINK_0.00398107170553497 FALSE 792.1 Papanicolaou smear of cervix or vagina with atypical squamous cells Female 299 1190 11 genitourinary black 1190, 299 297, 60 297, 70 297, 86 298, 83 0.173 0.0652 0.00787 2.104 1.19 1.05 1.35 0.208 0.198 0.293 0.5331 1.23 0.836 1.81 0.397 0.192 0.0384 1.415 1.49 1.02 2.17 0.389 0.195 0.0466 1.331 1.48 1.01 2.16 PRS_PLINK_0.00398107170553497 FALSE 794 Abnormal results of other function studies (bladder, pancreas, placenta, spleen, etc) Both 68 588 17 symptoms purple 588, 68 146, 18 147, 22 147, 13 147, 15 -0.213 0.137 0.121 0.9184 0.808 0.617 1.06 0.094 0.342 0.784 0.106 1.1 0.562 2.15 -0.466 0.395 0.237 0.625 0.627 0.289 1.36 -0.214 0.376 0.57 0.244 0.808 0.386 1.69 PRS_PLINK_0.00398107170553497 FALSE 795 Other and nonspecific abnormal cytological, histological and immunological findings Both 532 2912 17 symptoms purple 2912, 532 727, 135 728, 129 728, 128 728, 140 0.0166 0.0481 0.731 0.1362 1.02 0.925 1.12 -0.0349 0.135 0.795 0.09943 0.966 0.742 1.26 -0.0577 0.136 0.672 0.1725 0.944 0.723 1.23 0.0664 0.136 0.626 0.2036 1.07 0.818 1.4 PRS_PLINK_0.00398107170553497 FALSE 795.8 Abnormal tumor markers Both 168 1160 17 symptoms purple 1160, 168 289, 50 290, 38 290, 44 290, 36 -0.146 0.0853 0.086 1.066 0.864 0.731 1.02 -0.304 0.237 0.199 0.7001 0.738 0.463 1.17 -0.226 0.227 0.321 0.4935 0.798 0.511 1.25 -0.502 0.242 0.0382 1.418 0.605 0.376 0.973 PRS_PLINK_0.00398107170553497 FALSE 795.81 Elevated carcinoembryonic antigen [CEA] Both 11 76 17 symptoms purple 76, 11 19, 4 19, 3 19, 3 19, 1 -0.344 0.382 0.369 0.4335 0.709 0.335 1.5 0.221 0.92 0.81 0.09168 1.25 0.206 7.57 -0.654 0.977 0.503 0.2982 0.52 0.0766 3.53 -2.02 1.33 0.13 0.8865 0.133 0.0098 1.81 PRS_PLINK_0.00398107170553497 TRUE 795.82 Elevated cancer antigen 125 [CA 125] Both 34 294 17 symptoms purple 294, 34 73, 7 73, 12 73, 9 74, 6 -0.107 0.189 0.572 0.2425 0.898 0.62 1.3 0.484 0.541 0.371 0.4305 1.62 0.562 4.68 0.285 0.521 0.585 0.2332 1.33 0.479 3.69 -0.292 0.592 0.622 0.2061 0.747 0.234 2.38 PRS_PLINK_0.00398107170553497 TRUE 796 Elevated prostate specific antigen [PSA] Male 171 450 11 genitourinary black 450, 171 113, 31 112, 43 112, 52 113, 45 0.121 0.1 0.23 0.6385 1.13 0.927 1.37 0.333 0.293 0.256 0.5913 1.39 0.785 2.48 0.64 0.297 0.0309 1.51 1.9 1.06 3.39 0.391 0.295 0.186 0.731 1.48 0.829 2.64 PRS_PLINK_0.00398107170553497 FALSE 797 Shock Both 71 551 17 symptoms purple 551, 71 138, 13 138, 20 137, 21 138, 17 0.051 0.125 0.683 0.1653 1.05 0.824 1.34 0.468 0.378 0.215 0.6667 1.6 0.762 3.35 0.476 0.374 0.203 0.6918 1.61 0.773 3.35 0.238 0.392 0.544 0.2648 1.27 0.589 2.73 PRS_PLINK_0.00398107170553497 FALSE 797.1 Cardiogenic shock Both 22 199 17 symptoms purple 199, 22 50, 3 50, 7 49, 5 50, 7 0.199 0.218 0.362 0.4411 1.22 0.795 1.87 0.727 0.731 0.32 0.4949 2.07 0.494 8.66 0.554 0.72 0.442 0.3546 1.74 0.424 7.14 1.36 0.756 0.0728 1.138 3.88 0.882 17.1 PRS_PLINK_0.00398107170553497 TRUE 798 Malaise and fatigue Both 2324 2907 17 symptoms purple 2907, 2324 727, 571 727, 615 726, 556 727, 581 0.0128 0.0292 0.66 0.1802 1.01 0.957 1.07 0.0633 0.0806 0.432 0.3643 1.07 0.91 1.25 -0.0279 0.0833 0.737 0.1324 0.972 0.826 1.14 0.0329 0.084 0.696 0.1576 1.03 0.877 1.22 PRS_PLINK_0.00398107170553497 FALSE 798.1 Chronic fatigue syndrome Both 390 1817 17 symptoms purple 1817, 390 455, 92 454, 94 454, 97 454, 107 0.0486 0.0573 0.396 0.4027 1.05 0.938 1.17 -0.0183 0.164 0.911 0.04043 0.982 0.712 1.35 0.0842 0.165 0.609 0.2151 1.09 0.787 1.5 0.166 0.164 0.311 0.5078 1.18 0.856 1.63 PRS_PLINK_0.00398107170553497 FALSE 800 Fracture of lower limb Both 448 2367 18 injuries & poisonings gray50 2367, 448 592, 115 592, 115 591, 105 592, 113 0.00248 0.0539 0.963 0.0162 1 0.902 1.11 0.0046 0.146 0.975 0.01107 1 0.755 1.34 -0.0647 0.151 0.667 0.1757 0.937 0.698 1.26 0.0368 0.15 0.807 0.09324 1.04 0.773 1.39 PRS_PLINK_0.00398107170553497 FALSE 800.1 Fracture of neck of femur Both 110 472 18 injuries & poisonings gray50 472, 110 118, 30 118, 29 118, 32 118, 19 -0.0823 0.107 0.442 0.3546 0.921 0.747 1.14 -0.0286 0.297 0.923 0.03467 0.972 0.543 1.74 0.0345 0.297 0.907 0.04227 1.04 0.579 1.85 -0.449 0.329 0.172 0.7656 0.638 0.335 1.22 PRS_PLINK_0.00398107170553497 FALSE 800.2 Fracture of unspecified part of femur Both 115 610 18 injuries & poisonings gray50 610, 115 153, 34 152, 28 152, 29 153, 24 -0.0396 0.105 0.707 0.1509 0.961 0.782 1.18 -0.252 0.287 0.379 0.4218 0.777 0.443 1.36 -0.14 0.279 0.617 0.2099 0.87 0.504 1.5 -0.364 0.297 0.221 0.6551 0.695 0.388 1.24 PRS_PLINK_0.00398107170553497 FALSE 800.3 Fracture of tibia and fibula Both 155 853 18 injuries & poisonings gray50 853, 155 214, 36 213, 41 213, 43 213, 35 -0.00353 0.0869 0.968 0.01428 0.996 0.84 1.18 0.154 0.248 0.535 0.272 1.17 0.717 1.9 0.152 0.256 0.554 0.2568 1.16 0.704 1.92 0.0723 0.267 0.787 0.1041 1.07 0.636 1.82 PRS_PLINK_0.00398107170553497 FALSE 800.4 Fracture of patella Both 84 360 18 injuries & poisonings gray50 360, 84 90, 21 90, 21 90, 17 90, 25 0.0834 0.123 0.499 0.3022 1.09 0.854 1.38 -0.117 0.358 0.743 0.1291 0.889 0.441 1.79 -0.175 0.371 0.637 0.1961 0.839 0.405 1.74 0.421 0.366 0.249 0.6029 1.52 0.744 3.12 PRS_PLINK_0.00398107170553497 FALSE 801 Fracture of ankle and foot Both 539 2535 18 injuries & poisonings gray50 2535, 539 634, 141 634, 122 633, 126 634, 150 0.0582 0.0498 0.242 0.6154 1.06 0.961 1.17 -0.144 0.137 0.292 0.5347 0.866 0.662 1.13 -0.102 0.139 0.463 0.3344 0.903 0.688 1.19 0.134 0.136 0.326 0.4873 1.14 0.876 1.49 PRS_PLINK_0.00398107170553497 FALSE 801.1 Fracture of foot Both 225 1248 18 injuries & poisonings gray50 1248, 225 312, 58 312, 54 312, 50 312, 63 0.052 0.0769 0.499 0.3021 1.05 0.906 1.22 -0.0639 0.206 0.756 0.1212 0.938 0.626 1.4 -0.104 0.213 0.625 0.2038 0.901 0.594 1.37 0.133 0.206 0.519 0.2846 1.14 0.762 1.71 PRS_PLINK_0.00398107170553497 FALSE 802 Fracture of pelvis Both 66 359 18 injuries & poisonings gray50 359, 66 90, 19 90, 11 89, 19 90, 17 0.0219 0.14 0.876 0.05748 1.02 0.777 1.35 -0.625 0.413 0.13 0.8849 0.535 0.238 1.2 -0.0823 0.37 0.824 0.08422 0.921 0.446 1.9 -0.166 0.374 0.657 0.1826 0.847 0.407 1.76 PRS_PLINK_0.00398107170553497 FALSE 803 Fracture of upper limb Both 452 2101 18 injuries & poisonings gray50 2101, 452 526, 129 525, 106 525, 98 525, 118 -0.0476 0.0536 0.374 0.4266 0.954 0.859 1.06 -0.245 0.148 0.0979 1.009 0.783 0.585 1.05 -0.291 0.151 0.0535 1.272 0.747 0.556 1 -0.119 0.149 0.426 0.3703 0.888 0.663 1.19 PRS_PLINK_0.00398107170553497 FALSE 803.1 Fracture of humerus Both 146 764 18 injuries & poisonings gray50 764, 146 191, 48 191, 36 191, 24 191, 37 -0.195 0.0919 0.0343 1.464 0.823 0.687 0.986 -0.322 0.244 0.187 0.729 0.725 0.45 1.17 -0.719 0.273 0.00847 2.072 0.487 0.285 0.832 -0.346 0.249 0.165 0.7828 0.707 0.434 1.15 PRS_PLINK_0.00398107170553497 FALSE 803.2 Fracture of radius and ulna Both 291 1233 18 injuries & poisonings gray50 1233, 291 309, 78 308, 68 308, 64 308, 81 0.00991 0.068 0.884 0.05347 1.01 0.884 1.15 -0.168 0.189 0.372 0.4293 0.845 0.584 1.22 -0.197 0.191 0.304 0.5171 0.821 0.565 1.2 0.0428 0.188 0.82 0.08599 1.04 0.722 1.51 PRS_PLINK_0.00398107170553497 FALSE 803.21 Colles' fracture Both 98 337 18 injuries & poisonings gray50 337, 98 85, 29 84, 19 84, 27 84, 23 0.0284 0.12 0.813 0.08995 1.03 0.813 1.3 -0.405 0.341 0.235 0.6281 0.667 0.342 1.3 0.033 0.326 0.919 0.03651 1.03 0.546 1.96 -0.156 0.338 0.643 0.1916 0.855 0.441 1.66 PRS_PLINK_0.00398107170553497 FALSE 803.3 Fracture of clavicle or scapula Both 87 393 18 injuries & poisonings gray50 393, 87 99, 28 98, 18 98, 18 98, 23 -0.044 0.118 0.71 0.1487 0.957 0.759 1.21 -0.546 0.342 0.11 0.9574 0.58 0.297 1.13 -0.518 0.343 0.13 0.8847 0.595 0.304 1.17 -0.238 0.32 0.458 0.3394 0.788 0.421 1.48 PRS_PLINK_0.00398107170553497 FALSE 804 Fracture of hand or wrist Both 349 1557 18 injuries & poisonings gray50 1557, 349 390, 94 389, 80 389, 82 389, 93 -0.02 0.0622 0.747 0.1265 0.98 0.868 1.11 -0.206 0.17 0.226 0.646 0.814 0.583 1.14 -0.147 0.173 0.397 0.4017 0.863 0.614 1.21 0.0204 0.171 0.905 0.04338 1.02 0.73 1.43 PRS_PLINK_0.00398107170553497 FALSE 805 Fracture of vertebral column without mention of spinal cord injury Both 231 1248 18 injuries & poisonings gray50 1248, 231 312, 53 312, 50 312, 66 312, 61 0.123 0.0749 0.0996 1.002 1.13 0.977 1.31 -0.116 0.216 0.589 0.2295 0.89 0.583 1.36 0.144 0.206 0.483 0.3157 1.16 0.771 1.73 0.121 0.212 0.566 0.2471 1.13 0.746 1.71 PRS_PLINK_0.00398107170553497 FALSE 807 Fracture of ribs Both 118 588 18 injuries & poisonings gray50 588, 118 147, 26 147, 29 147, 34 147, 29 0.141 0.1 0.16 0.7963 1.15 0.946 1.4 0.13 0.292 0.656 0.1832 1.14 0.643 2.02 0.315 0.292 0.28 0.5529 1.37 0.774 2.43 0.2 0.301 0.506 0.2956 1.22 0.677 2.21 PRS_PLINK_0.00398107170553497 FALSE 809 Fracture of unspecified bones Both 504 2804 18 injuries & poisonings gray50 2804, 504 701, 126 701, 131 701, 118 701, 128 0.0138 0.0504 0.784 0.1055 1.01 0.919 1.12 0.00795 0.138 0.954 0.02044 1.01 0.769 1.32 -0.0955 0.143 0.505 0.2965 0.909 0.686 1.2 0.0939 0.142 0.509 0.2929 1.1 0.831 1.45 PRS_PLINK_0.00398107170553497 FALSE 816 Cerebral laceration and contusion Both 8 42 18 injuries & poisonings gray50 42, 8 11, 1 10, 0 10, 5 11, 2 0.294 0.528 0.578 0.2384 1.34 0.476 3.78 -0.371 1.47 0.801 0.09664 0.69 0.0389 12.2 1.53 1.27 0.229 0.6393 4.62 0.381 56 -0.219 1.45 0.88 0.05571 0.803 0.0471 13.7 PRS_PLINK_0.00398107170553497 TRUE 817 Concussion Both 191 1104 18 injuries & poisonings gray50 1104, 191 275, 53 276, 49 276, 50 276, 39 -0.0697 0.0807 0.387 0.4118 0.933 0.796 1.09 -0.043 0.219 0.845 0.07338 0.958 0.624 1.47 -0.0427 0.219 0.846 0.07278 0.958 0.624 1.47 -0.32 0.235 0.174 0.76 0.726 0.458 1.15 PRS_PLINK_0.00398107170553497 FALSE 818 Intracranial hemorrhage (injury) Both 53 295 18 injuries & poisonings gray50 295, 53 74, 5 74, 19 73, 20 74, 9 0.0406 0.151 0.789 0.1031 1.04 0.774 1.4 1.32 0.511 0.00986 2.006 3.74 1.37 10.2 1.15 0.521 0.0276 1.559 3.15 1.13 8.76 0.415 0.571 0.468 0.3299 1.51 0.494 4.64 PRS_PLINK_0.00398107170553497 FALSE 818.1 Subdural hemorrhage (injury) Both 17 81 18 injuries & poisonings gray50 81, 17 21, 0 20, 6 20, 8 20, 3 0.178 0.298 0.55 0.2598 1.2 0.666 2.15 2.61 1.46 0.0737 1.132 13.7 0.778 240 1.91 1.24 0.123 0.9088 6.75 0.595 76.5 2.04 1.51 0.175 0.7559 7.71 0.402 148 PRS_PLINK_0.00398107170553497 TRUE 818.2 Subarachnoid hemorrhage (injury) Both 12 92 18 injuries & poisonings gray50 92, 12 23, 2 23, 3 23, 6 23, 1 -0.0237 0.3 0.937 0.02822 0.977 0.542 1.76 -0.0446 0.866 0.959 0.01821 0.956 0.175 5.22 0.806 0.81 0.32 0.4952 2.24 0.458 11 -0.635 1.31 0.628 0.2023 0.53 0.0408 6.89 PRS_PLINK_0.00398107170553497 TRUE 819 Skull and face fracture and other intercranial injury Both 364 2249 18 injuries & poisonings gray50 2249, 364 562, 93 562, 94 562, 99 562, 78 -0.0112 0.0578 0.846 0.07281 0.989 0.883 1.11 0.00259 0.158 0.987 0.005705 1 0.735 1.37 0.0837 0.159 0.599 0.2228 1.09 0.796 1.49 -0.172 0.17 0.312 0.5057 0.842 0.603 1.18 PRS_PLINK_0.00398107170553497 FALSE 830 Dislocation Both 727 3534 18 injuries & poisonings gray50 3534, 727 884, 183 883, 162 883, 174 884, 207 0.0505 0.0419 0.228 0.6427 1.05 0.969 1.14 -0.149 0.119 0.213 0.6718 0.862 0.682 1.09 -0.0683 0.119 0.565 0.2483 0.934 0.74 1.18 0.0772 0.116 0.507 0.2949 1.08 0.86 1.36 PRS_PLINK_0.00398107170553497 FALSE 835 Internal derangement of knee Both 468 2207 18 injuries & poisonings gray50 2207, 468 552, 102 552, 123 551, 112 552, 131 0.0633 0.0533 0.235 0.6293 1.07 0.96 1.18 0.191 0.149 0.199 0.7017 1.21 0.904 1.62 0.0831 0.153 0.587 0.2313 1.09 0.805 1.47 0.277 0.152 0.0684 1.165 1.32 0.979 1.78 PRS_PLINK_0.00398107170553497 FALSE 836 Traumatic arthropathy Both 88 480 18 injuries & poisonings gray50 480, 88 120, 27 120, 27 120, 17 120, 17 -0.105 0.123 0.391 0.408 0.9 0.708 1.14 0.053 0.302 0.861 0.06517 1.05 0.583 1.91 -0.471 0.356 0.185 0.7317 0.624 0.311 1.25 -0.348 0.344 0.312 0.5064 0.706 0.36 1.39 PRS_PLINK_0.00398107170553497 FALSE 840 Sprains and strains Both 1647 3386 18 injuries & poisonings gray50 3386, 1647 847, 408 846, 428 846, 406 847, 404 0.00632 0.031 0.838 0.07661 1.01 0.947 1.07 0.0508 0.0858 0.553 0.2569 1.05 0.889 1.24 0.0126 0.0878 0.885 0.05284 1.01 0.853 1.2 -0.0281 0.0892 0.753 0.1231 0.972 0.816 1.16 PRS_PLINK_0.00398107170553497 FALSE 840.1 Muscle/tendon sprain Both 140 472 18 injuries & poisonings gray50 472, 140 118, 33 118, 34 118, 28 118, 45 0.107 0.108 0.321 0.4936 1.11 0.901 1.38 0.0613 0.28 0.827 0.08259 1.06 0.614 1.84 -0.133 0.286 0.642 0.1925 0.875 0.499 1.53 0.324 0.277 0.242 0.6153 1.38 0.803 2.38 PRS_PLINK_0.00398107170553497 FALSE 840.2 Rotator cuff (capsule) sprain Both 336 1395 18 injuries & poisonings gray50 1395, 336 349, 89 349, 76 348, 74 349, 97 0.0278 0.0624 0.656 0.1829 1.03 0.91 1.16 -0.111 0.178 0.533 0.2732 0.895 0.632 1.27 -0.164 0.18 0.361 0.4429 0.849 0.597 1.21 0.0836 0.174 0.631 0.2001 1.09 0.773 1.53 PRS_PLINK_0.00398107170553497 FALSE 840.3 Joint/ligament sprain Both 526 2274 18 injuries & poisonings gray50 2274, 526 569, 117 568, 146 568, 130 569, 133 0.0517 0.0498 0.299 0.5239 1.05 0.955 1.16 0.202 0.141 0.151 0.8219 1.22 0.929 1.61 0.109 0.145 0.453 0.3442 1.11 0.839 1.48 0.13 0.146 0.371 0.4304 1.14 0.856 1.52 PRS_PLINK_0.00398107170553497 FALSE 841 Sprains and strains of back and neck Both 369 1632 18 injuries & poisonings gray50 1632, 369 408, 85 408, 97 408, 100 408, 87 0.0331 0.0608 0.586 0.2321 1.03 0.918 1.16 0.0704 0.167 0.673 0.1717 1.07 0.774 1.49 0.158 0.168 0.346 0.4608 1.17 0.843 1.63 -0.0315 0.175 0.857 0.06685 0.969 0.688 1.37 PRS_PLINK_0.00398107170553497 FALSE 842 Other sprains and strains Both 309 1297 18 injuries & poisonings gray50 1297, 309 325, 80 324, 69 324, 98 324, 62 -0.0166 0.0655 0.801 0.09657 0.984 0.865 1.12 -0.143 0.187 0.446 0.3508 0.867 0.601 1.25 0.22 0.176 0.212 0.673 1.25 0.882 1.76 -0.207 0.196 0.289 0.5389 0.813 0.554 1.19 PRS_PLINK_0.00398107170553497 FALSE 850 Hemorrhage or hematoma complicating a procedure Both 249 2227 18 injuries & poisonings gray50 2227, 249 557, 55 557, 60 556, 57 557, 77 0.129 0.0694 0.064 1.194 1.14 0.993 1.3 0.0976 0.194 0.615 0.2108 1.1 0.753 1.61 0.0138 0.199 0.945 0.02473 1.01 0.686 1.5 0.321 0.19 0.0908 1.042 1.38 0.95 2 PRS_PLINK_0.00398107170553497 FALSE 851 Complications of transplants and reattached limbs Both 324 2779 18 injuries & poisonings gray50 2779, 324 695, 85 695, 86 694, 71 695, 82 -0.0202 0.0606 0.738 0.1317 0.98 0.87 1.1 0.0358 0.162 0.825 0.08334 1.04 0.754 1.43 -0.121 0.173 0.485 0.3141 0.886 0.632 1.24 0.0026 0.171 0.988 0.005321 1 0.718 1.4 PRS_PLINK_0.00398107170553497 FALSE 853 Complication of colostomy or enterostomy Both 48 455 18 injuries & poisonings gray50 455, 48 114, 14 114, 12 113, 7 114, 15 -0.00595 0.15 0.968 0.01397 0.994 0.741 1.33 -0.269 0.405 0.506 0.2956 0.764 0.346 1.69 -0.687 0.467 0.141 0.8501 0.503 0.202 1.26 0.0408 0.401 0.919 0.03669 1.04 0.475 2.29 PRS_PLINK_0.00398107170553497 TRUE 854 Complications of cardiac/vascular device, implant, and graft Both 187 1961 18 injuries & poisonings gray50 1961, 187 491, 45 490, 41 490, 52 490, 49 -0.0069 0.0784 0.93 0.03157 0.993 0.852 1.16 -0.135 0.223 0.545 0.2634 0.874 0.565 1.35 0.0932 0.214 0.663 0.1782 1.1 0.722 1.67 0.0723 0.219 0.741 0.1301 1.08 0.7 1.65 PRS_PLINK_0.00398107170553497 FALSE 855 Complication of nervous system device, implant, and graft Both 15 264 18 injuries & poisonings gray50 264, 15 66, 2 66, 9 66, 2 66, 2 -0.0331 0.249 0.894 0.04854 0.967 0.594 1.58 1.22 0.663 0.0667 1.176 3.37 0.92 12.4 0.317 0.796 0.69 0.1609 1.37 0.289 6.53 0.339 0.863 0.695 0.1582 1.4 0.259 7.61 PRS_PLINK_0.00398107170553497 TRUE 856 Vascular complications of surgery and medical procedures Both 36 326 18 injuries & poisonings gray50 326, 36 82, 9 81, 6 81, 10 82, 11 0.0719 0.178 0.687 0.1632 1.07 0.758 1.52 -0.389 0.527 0.46 0.337 0.678 0.241 1.9 0.119 0.491 0.809 0.09212 1.13 0.43 2.95 0.197 0.468 0.674 0.1711 1.22 0.486 3.05 PRS_PLINK_0.00398107170553497 TRUE 857 Mechanical complication of unspecified genitourinary device, implant, and graft Both 143 1432 18 injuries & poisonings gray50 1432, 143 358, 29 358, 36 358, 42 358, 36 -0.00737 0.0896 0.934 0.02945 0.993 0.833 1.18 0.159 0.256 0.533 0.2734 1.17 0.711 1.94 0.44 0.253 0.0823 1.085 1.55 0.945 2.55 0.133 0.264 0.614 0.2122 1.14 0.681 1.92 PRS_PLINK_0.00398107170553497 FALSE 858 Complication of internal orthopedic device Both 261 2251 18 injuries & poisonings gray50 2251, 261 563, 54 563, 70 562, 59 563, 78 0.0969 0.0663 0.144 0.8427 1.1 0.968 1.25 0.303 0.19 0.112 0.95 1.35 0.932 1.97 0.195 0.199 0.328 0.4842 1.22 0.822 1.8 0.449 0.19 0.0183 1.736 1.57 1.08 2.28 PRS_PLINK_0.00398107170553497 FALSE 859 Complication due to other implant and internal device Both 238 2300 18 injuries & poisonings gray50 2300, 238 575, 45 575, 69 575, 71 575, 52 0.00277 0.0693 0.968 0.01406 1 0.875 1.15 0.406 0.199 0.0408 1.389 1.5 1.02 2.22 0.479 0.2 0.0167 1.777 1.61 1.09 2.39 0.23 0.217 0.289 0.5391 1.26 0.823 1.92 PRS_PLINK_0.00398107170553497 FALSE 860 Bone marrow or stem cell transplant Both 24 159 2 neoplasms darkcyan 159, 24 40, 9 40, 3 39, 8 40, 4 -0.0103 0.216 0.962 0.01685 0.99 0.648 1.51 -0.718 0.732 0.326 0.4865 0.488 0.116 2.05 0.0553 0.545 0.919 0.03659 1.06 0.363 3.07 -0.366 0.632 0.562 0.25 0.693 0.201 2.39 PRS_PLINK_0.00398107170553497 TRUE 870 Open wounds of head; neck; and trunk Both 578 3756 18 injuries & poisonings gray50 3756, 578 938, 153 939, 151 939, 138 939, 136 -0.0512 0.0458 0.263 0.5797 0.95 0.869 1.04 -0.0111 0.125 0.929 0.03208 0.989 0.775 1.26 -0.134 0.129 0.301 0.5214 0.875 0.679 1.13 -0.147 0.131 0.262 0.5819 0.863 0.667 1.12 PRS_PLINK_0.00398107170553497 FALSE 870.1 Open wound or laceration of eye or eyelid Both 32 174 18 injuries & poisonings gray50 174, 32 44, 10 43, 9 43, 8 44, 5 -0.256 0.221 0.246 0.6085 0.774 0.502 1.19 -0.152 0.542 0.779 0.1084 0.859 0.297 2.49 -0.0915 0.551 0.868 0.06143 0.913 0.31 2.69 -0.58 0.611 0.342 0.4657 0.56 0.169 1.85 PRS_PLINK_0.00398107170553497 TRUE 870.2 Open wound of ear Both 27 153 18 injuries & poisonings gray50 153, 27 39, 11 38, 7 38, 6 38, 3 -0.556 0.231 0.0161 1.792 0.573 0.364 0.902 -0.176 0.529 0.74 0.1309 0.839 0.298 2.36 -0.441 0.566 0.437 0.36 0.644 0.212 1.95 -1.22 0.675 0.0714 1.147 0.296 0.079 1.11 PRS_PLINK_0.00398107170553497 TRUE 870.3 Other open wound of head and face Both 230 1381 18 injuries & poisonings gray50 1381, 230 346, 60 345, 50 345, 67 345, 53 -0.0203 0.074 0.784 0.1058 0.98 0.848 1.13 -0.172 0.206 0.402 0.3954 0.842 0.562 1.26 0.157 0.197 0.425 0.3715 1.17 0.795 1.72 -0.0992 0.211 0.639 0.1946 0.906 0.598 1.37 PRS_PLINK_0.00398107170553497 FALSE 870.4 Open wound of nose and sinus Both 32 236 18 injuries & poisonings gray50 236, 32 59, 10 59, 8 59, 8 59, 6 -0.311 0.196 0.112 0.9507 0.732 0.499 1.08 -0.202 0.521 0.698 0.1564 0.817 0.294 2.27 -0.126 0.516 0.808 0.09279 0.882 0.321 2.43 -0.503 0.558 0.368 0.4344 0.605 0.203 1.81 PRS_PLINK_0.00398107170553497 TRUE 870.5 Open wound of lip and mouth Both 46 248 18 injuries & poisonings gray50 248, 46 62, 11 62, 9 62, 15 62, 11 0.182 0.169 0.28 0.5525 1.2 0.862 1.67 0.0236 0.494 0.962 0.0169 1.02 0.389 2.7 0.969 0.516 0.0602 1.22 2.64 0.959 7.25 0.238 0.492 0.629 0.2011 1.27 0.483 3.33 PRS_PLINK_0.00398107170553497 TRUE 870.6 Open wound of neck Both 11 172 18 injuries & poisonings gray50 172, 11 43, 4 43, 4 43, 2 43, 1 -0.446 0.335 0.183 0.7387 0.64 0.332 1.23 -0.153 0.727 0.833 0.07943 0.858 0.206 3.56 -1.3 0.893 0.147 0.8327 0.274 0.0476 1.58 -1.07 0.917 0.243 0.6149 0.342 0.0567 2.07 PRS_PLINK_0.00398107170553497 TRUE 870.8 Open wound of genital organs Both 23 184 18 injuries & poisonings gray50 184, 23 46, 4 46, 8 46, 4 46, 7 0.1 0.203 0.622 0.2065 1.11 0.743 1.65 0.497 0.641 0.438 0.3584 1.64 0.468 5.78 -0.106 0.704 0.88 0.05549 0.899 0.226 3.57 0.264 0.633 0.676 0.17 1.3 0.377 4.51 PRS_PLINK_0.00398107170553497 TRUE 871 Open wounds of extremities Both 590 3431 18 injuries & poisonings gray50 3431, 590 857, 166 858, 133 857, 156 858, 135 -0.0332 0.0454 0.465 0.3324 0.967 0.885 1.06 -0.211 0.127 0.0983 1.008 0.81 0.631 1.04 -0.107 0.124 0.388 0.4106 0.898 0.704 1.15 -0.225 0.13 0.0838 1.077 0.799 0.619 1.03 PRS_PLINK_0.00398107170553497 FALSE 871.1 Open wound of hand except finger(s) Both 113 605 18 injuries & poisonings gray50 605, 113 151, 32 151, 27 151, 26 151, 28 -0.0237 0.102 0.816 0.08832 0.977 0.8 1.19 -0.0738 0.289 0.799 0.09766 0.929 0.527 1.64 -0.205 0.298 0.493 0.3075 0.815 0.454 1.46 -0.113 0.292 0.7 0.155 0.894 0.504 1.58 PRS_PLINK_0.00398107170553497 FALSE 871.2 Open wound of finger(s) Both 206 1060 18 injuries & poisonings gray50 1060, 206 265, 59 265, 46 265, 52 265, 49 -0.0287 0.079 0.716 0.1451 0.972 0.832 1.13 -0.26 0.221 0.238 0.6242 0.771 0.5 1.19 -0.247 0.215 0.25 0.6024 0.781 0.513 1.19 -0.303 0.221 0.171 0.7675 0.739 0.479 1.14 PRS_PLINK_0.00398107170553497 FALSE 871.3 Open wound of foot except toe(s) alone Both 63 485 18 injuries & poisonings gray50 485, 63 121, 18 121, 13 121, 17 121, 15 -0.0226 0.137 0.869 0.06087 0.978 0.748 1.28 -0.318 0.388 0.413 0.3839 0.728 0.34 1.56 -0.0694 0.374 0.853 0.06928 0.933 0.449 1.94 -0.117 0.393 0.766 0.1159 0.889 0.411 1.92 PRS_PLINK_0.00398107170553497 FALSE 871.4 Open wound of toe(s) Both 47 380 18 injuries & poisonings gray50 380, 47 95, 16 95, 7 95, 12 95, 12 0.0279 0.156 0.858 0.06652 1.03 0.758 1.4 -0.76 0.466 0.103 0.9878 0.468 0.188 1.17 -0.289 0.416 0.487 0.3129 0.749 0.331 1.69 -0.177 0.417 0.671 0.1735 0.838 0.37 1.9 PRS_PLINK_0.00398107170553497 TRUE 872 Traumatic amputation Both 38 449 18 injuries & poisonings gray50 449, 38 112, 10 112, 5 112, 9 112, 14 0.206 0.18 0.251 0.5996 1.23 0.864 1.75 -0.621 0.528 0.24 0.6204 0.537 0.191 1.51 -0.0885 0.466 0.849 0.07094 0.915 0.367 2.28 0.394 0.432 0.361 0.4422 1.48 0.636 3.46 PRS_PLINK_0.00398107170553497 TRUE 874 Complication of amputation stump Both 11 131 18 injuries & poisonings gray50 131, 11 33, 2 33, 3 32, 3 33, 3 0.169 0.333 0.611 0.214 1.18 0.617 2.27 0.29 0.943 0.758 0.1202 1.34 0.211 8.48 0.338 0.774 0.663 0.1787 1.4 0.308 6.38 0.33 0.797 0.679 0.1684 1.39 0.292 6.64 PRS_PLINK_0.00398107170553497 TRUE 875 Non-healing surgical wound Both 51 587 18 injuries & poisonings gray50 587, 51 147, 9 147, 14 146, 12 147, 16 0.165 0.142 0.244 0.6126 1.18 0.893 1.56 0.365 0.415 0.379 0.4218 1.44 0.639 3.25 0.315 0.431 0.464 0.3331 1.37 0.589 3.19 0.424 0.414 0.306 0.514 1.53 0.678 3.44 PRS_PLINK_0.00398107170553497 FALSE 876 Posttraumatic wound infection not elsewhere classified Both 86 852 18 injuries & poisonings gray50 852, 86 213, 24 213, 24 213, 14 213, 24 -0.0685 0.114 0.546 0.2626 0.934 0.748 1.17 -0.0257 0.299 0.931 0.03087 0.975 0.543 1.75 -0.61 0.347 0.0788 1.104 0.543 0.275 1.07 -0.0639 0.308 0.836 0.07798 0.938 0.513 1.72 PRS_PLINK_0.00398107170553497 FALSE 907 Injuries to the nervous system Both 103 947 18 injuries & poisonings gray50 947, 103 237, 29 237, 29 236, 28 237, 17 -0.113 0.108 0.297 0.5267 0.893 0.722 1.1 0.0356 0.284 0.9 0.0456 1.04 0.594 1.81 0.0815 0.296 0.783 0.1061 1.08 0.607 1.94 -0.385 0.339 0.256 0.5918 0.681 0.35 1.32 PRS_PLINK_0.00398107170553497 FALSE 910 Superficial injury, infected Both 22 127 18 injuries & poisonings gray50 127, 22 32, 8 32, 2 31, 5 32, 7 0.0658 0.232 0.776 0.1099 1.07 0.678 1.68 -1.33 0.762 0.08 1.097 0.263 0.0592 1.17 -0.416 0.614 0.498 0.3032 0.659 0.198 2.2 -0.427 0.682 0.531 0.2749 0.652 0.172 2.48 PRS_PLINK_0.00398107170553497 TRUE 911 Blister Both 51 358 18 injuries & poisonings gray50 358, 51 90, 13 89, 7 89, 18 90, 13 0.092 0.144 0.523 0.2816 1.1 0.827 1.45 -0.683 0.489 0.162 0.7897 0.505 0.194 1.32 0.176 0.403 0.662 0.1793 1.19 0.541 2.63 -0.0679 0.426 0.873 0.05882 0.934 0.405 2.15 PRS_PLINK_0.00398107170553497 FALSE 912 Insect bite Both 143 690 18 injuries & poisonings gray50 690, 143 173, 31 172, 44 172, 27 173, 40 0.0163 0.0948 0.864 0.06355 1.02 0.844 1.22 0.475 0.265 0.0732 1.135 1.61 0.956 2.71 -0.09 0.288 0.755 0.1222 0.914 0.52 1.61 0.144 0.273 0.597 0.2242 1.16 0.677 1.97 PRS_PLINK_0.00398107170553497 FALSE 913 Toxic effect of venom Both 102 485 18 injuries & poisonings gray50 485, 102 122, 20 121, 29 121, 26 121, 27 0.0556 0.114 0.625 0.204 1.06 0.846 1.32 0.311 0.32 0.331 0.4806 1.36 0.729 2.55 0.142 0.327 0.664 0.1776 1.15 0.607 2.19 0.285 0.333 0.393 0.4062 1.33 0.692 2.55 PRS_PLINK_0.00398107170553497 FALSE 916 Contusion Both 909 4049 18 injuries & poisonings gray50 4049, 909 1012, 230 1012, 231 1012, 198 1012, 250 0.00507 0.0379 0.893 0.04895 1.01 0.933 1.08 0.0142 0.104 0.891 0.04999 1.01 0.827 1.24 -0.143 0.109 0.189 0.7235 0.866 0.699 1.07 0.0738 0.105 0.484 0.3151 1.08 0.876 1.32 PRS_PLINK_0.00398107170553497 FALSE 930 Allergic reaction to food Both 162 646 18 injuries & poisonings gray50 646, 162 162, 46 161, 31 161, 39 162, 46 0.0755 0.0924 0.414 0.383 1.08 0.9 1.29 -0.28 0.264 0.29 0.5373 0.756 0.45 1.27 -0.0776 0.255 0.761 0.1185 0.925 0.561 1.53 0.00872 0.255 0.973 0.01202 1.01 0.612 1.66 PRS_PLINK_0.00398107170553497 FALSE 931 Contact dermatitis and other eczema due to plants [except food] Both 189 652 13 dermatologic firebrick 652, 189 163, 47 163, 38 163, 61 163, 43 0.0413 0.0896 0.645 0.1905 1.04 0.874 1.24 -0.268 0.252 0.289 0.5393 0.765 0.466 1.25 0.367 0.241 0.129 0.891 1.44 0.899 2.32 -0.0137 0.254 0.957 0.01918 0.986 0.6 1.62 PRS_PLINK_0.00398107170553497 FALSE 938 Dermatitis due to solar radiation Both 1421 2072 13 dermatologic firebrick 2072, 1421 518, 391 518, 329 518, 354 518, 346 -0.0358 0.0369 0.332 0.4789 0.965 0.898 1.04 -0.222 0.102 0.0296 1.528 0.801 0.656 0.978 -0.132 0.102 0.197 0.7061 0.876 0.717 1.07 -0.156 0.104 0.135 0.8706 0.855 0.697 1.05 PRS_PLINK_0.00398107170553497 FALSE 938.1 Acute dermatitis due to solar radiation Both 45 211 13 dermatologic firebrick 211, 45 53, 8 53, 11 52, 12 53, 14 0.271 0.189 0.152 0.8173 1.31 0.905 1.9 0.292 0.531 0.583 0.2344 1.34 0.473 3.79 0.678 0.523 0.194 0.7112 1.97 0.707 5.49 0.783 0.554 0.158 0.8018 2.19 0.738 6.49 PRS_PLINK_0.00398107170553497 TRUE 938.2 Chronic dermatitis due to solar radiation Both 1388 2050 13 dermatologic firebrick 2050, 1388 513, 385 512, 324 512, 346 513, 332 -0.0458 0.0372 0.218 0.6609 0.955 0.888 1.03 -0.226 0.103 0.0278 1.556 0.798 0.653 0.976 -0.148 0.103 0.151 0.8215 0.863 0.705 1.06 -0.186 0.105 0.0774 1.112 0.83 0.675 1.02 PRS_PLINK_0.00398107170553497 FALSE 939 Atopic/contact dermatitis due to other or unspecified Both 1655 2206 13 dermatologic firebrick 2206, 1655 552, 442 551, 421 551, 404 552, 388 -0.0188 0.0344 0.585 0.2329 0.981 0.917 1.05 -0.0473 0.094 0.615 0.2111 0.954 0.793 1.15 -0.0656 0.0963 0.495 0.305 0.936 0.775 1.13 -0.0977 0.0978 0.318 0.4978 0.907 0.749 1.1 PRS_PLINK_0.00398107170553497 FALSE 939.1 Contact and allergic dermatitis of eyelid Both 37 103 13 dermatologic firebrick 103, 37 26, 11 26, 7 25, 14 26, 5 0.435 0.552 0.43 0.3667 1.55 0.524 4.56 PRS_PLINK_0.00398107170553497 TRUE 941 Adverse reaction to serum or vaccine Both 29 189 18 injuries & poisonings gray50 189, 29 48, 8 47, 8 47, 7 47, 6 -0.169 0.204 0.408 0.3894 0.845 0.566 1.26 -0.205 0.558 0.713 0.1469 0.814 0.273 2.43 -0.387 0.611 0.526 0.2787 0.679 0.205 2.25 -0.505 0.615 0.412 0.3856 0.603 0.181 2.02 PRS_PLINK_0.00398107170553497 TRUE 942 Infusion and transfusion reaction Both 33 175 18 injuries & poisonings gray50 175, 33 44, 5 44, 7 43, 11 44, 10 0.11 0.212 0.606 0.2179 1.12 0.736 1.69 0.486 0.663 0.463 0.3342 1.63 0.444 5.96 1.26 0.677 0.063 1.201 3.52 0.934 13.3 1.08 0.755 0.153 0.8158 2.94 0.67 12.9 PRS_PLINK_0.00398107170553497 TRUE 946 Anaphylactic shock NOS Both 116 454 18 injuries & poisonings gray50 454, 116 114, 28 113, 30 113, 26 114, 32 0.0487 0.113 0.666 0.1767 1.05 0.842 1.31 0.129 0.307 0.674 0.1715 1.14 0.624 2.08 0.0892 0.321 0.781 0.1073 1.09 0.583 2.05 0.343 0.325 0.292 0.5353 1.41 0.745 2.67 PRS_PLINK_0.00398107170553497 FALSE 947 Urticaria Both 268 1087 13 dermatologic firebrick 1087, 268 272, 55 272, 73 271, 76 272, 64 0.0375 0.0709 0.597 0.2241 1.04 0.904 1.19 0.279 0.2 0.164 0.7863 1.32 0.893 1.96 0.267 0.205 0.192 0.7176 1.31 0.875 1.95 0.0365 0.212 0.863 0.06375 1.04 0.684 1.57 PRS_PLINK_0.00398107170553497 FALSE 949 Allergies, other Both 1616 2207 18 injuries & poisonings gray50 2207, 1616 552, 416 552, 393 551, 413 552, 394 0.043 0.0345 0.212 0.6728 1.04 0.976 1.12 -0.0452 0.0971 0.642 0.1926 0.956 0.79 1.16 0.0784 0.0973 0.42 0.3768 1.08 0.894 1.31 0.0201 0.0994 0.84 0.07584 1.02 0.84 1.24 PRS_PLINK_0.00398107170553497 FALSE 952 Spinal cord injury without evidence of spinal bone injury Both 60 443 18 injuries & poisonings gray50 443, 60 111, 15 111, 7 110, 17 111, 21 0.151 0.142 0.289 0.5396 1.16 0.88 1.54 -0.605 0.463 0.191 0.7181 0.546 0.221 1.35 0.206 0.385 0.592 0.2275 1.23 0.578 2.61 0.347 0.365 0.341 0.4667 1.41 0.692 2.89 PRS_PLINK_0.00398107170553497 FALSE 957 Injury to other and unspecified nerves Both 20 137 18 injuries & poisonings gray50 137, 20 34, 4 34, 1 34, 9 34, 6 0.159 0.243 0.512 0.2904 1.17 0.729 1.89 -1.58 1.02 0.12 0.921 0.205 0.0279 1.51 0.669 0.659 0.31 0.5088 1.95 0.537 7.1 -0.14 0.76 0.854 0.0685 0.87 0.196 3.85 PRS_PLINK_0.00398107170553497 TRUE 958 Certain early complications of trauma or procedure Both 137 1264 18 injuries & poisonings gray50 1264, 137 316, 37 316, 33 316, 32 316, 35 -0.0315 0.0932 0.735 0.1335 0.969 0.807 1.16 -0.107 0.251 0.669 0.1748 0.898 0.549 1.47 -0.245 0.257 0.34 0.4681 0.783 0.473 1.3 -0.107 0.253 0.671 0.1734 0.898 0.547 1.47 PRS_PLINK_0.00398107170553497 FALSE 958.1 Postoperative shock Both 25 148 18 injuries & poisonings gray50 148, 25 37, 10 37, 7 37, 4 37, 4 -0.384 0.244 0.116 0.9373 0.681 0.422 1.1 -0.2 0.56 0.721 0.1423 0.819 0.273 2.45 -1.16 0.687 0.0912 1.04 0.313 0.0815 1.2 -0.929 0.695 0.181 0.7417 0.395 0.101 1.54 PRS_PLINK_0.00398107170553497 TRUE 958.2 Traumatic and surgical subcutaneous emphysema Both 15 101 18 injuries & poisonings gray50 101, 15 26, 5 25, 3 25, 6 25, 1 -0.168 0.286 0.555 0.2555 0.845 0.483 1.48 -0.0734 0.77 0.924 0.03431 0.929 0.206 4.2 0.27 0.709 0.703 0.1528 1.31 0.326 5.26 -1.67 1.04 0.107 0.9691 0.188 0.0246 1.44 PRS_PLINK_0.00398107170553497 TRUE 960 Poisoning by antibiotics Both 330 2380 18 injuries & poisonings gray50 2380, 330 595, 75 595, 96 595, 82 595, 77 0.048 0.0602 0.425 0.3712 1.05 0.932 1.18 0.261 0.166 0.115 0.9379 1.3 0.938 1.8 0.175 0.174 0.313 0.5043 1.19 0.848 1.67 0.0618 0.178 0.728 0.1377 1.06 0.751 1.51 PRS_PLINK_0.00398107170553497 FALSE 960.1 Adverse effects of antibacterials (not penicillins) Both 61 425 18 injuries & poisonings gray50 425, 61 107, 17 106, 21 106, 13 106, 10 -0.117 0.139 0.4 0.3982 0.89 0.678 1.17 0.233 0.361 0.519 0.2848 1.26 0.622 2.56 -0.143 0.386 0.711 0.1482 0.867 0.406 1.85 -0.367 0.409 0.37 0.4322 0.693 0.311 1.54 PRS_PLINK_0.00398107170553497 FALSE 960.2 Allergy/adverse effect of penicillin Both 210 1760 18 injuries & poisonings gray50 1760, 210 440, 46 440, 53 440, 54 440, 57 0.112 0.0747 0.135 0.869 1.12 0.966 1.29 0.149 0.212 0.482 0.317 1.16 0.766 1.76 0.204 0.213 0.337 0.4724 1.23 0.808 1.86 0.282 0.216 0.192 0.7156 1.33 0.868 2.03 PRS_PLINK_0.00398107170553497 FALSE 961 Poisoning by other anti-infectives Both 115 641 18 injuries & poisonings gray50 641, 115 161, 25 160, 25 160, 27 160, 38 0.143 0.104 0.166 0.7787 1.15 0.942 1.41 -0.0691 0.307 0.822 0.0853 0.933 0.512 1.7 0.0403 0.312 0.897 0.04705 1.04 0.564 1.92 0.442 0.29 0.127 0.8954 1.56 0.882 2.74 PRS_PLINK_0.00398107170553497 FALSE 961.1 Poisoning/allergy of sulfonamides Both 162 1300 18 injuries & poisonings gray50 1300, 162 325, 34 325, 49 325, 36 325, 43 0.0746 0.0848 0.379 0.421 1.08 0.912 1.27 0.388 0.236 0.1 0.9998 1.47 0.928 2.34 0.0893 0.253 0.724 0.1404 1.09 0.666 1.79 0.237 0.247 0.338 0.4708 1.27 0.78 2.06 PRS_PLINK_0.00398107170553497 FALSE 962 Poisoning by hormones and synthetic substitutes Both 148 898 18 injuries & poisonings gray50 898, 148 225, 45 224, 35 224, 34 225, 34 -0.143 0.0906 0.115 0.9406 0.867 0.726 1.04 -0.303 0.248 0.221 0.6554 0.738 0.454 1.2 -0.17 0.251 0.5 0.3012 0.844 0.516 1.38 -0.248 0.251 0.324 0.4898 0.781 0.477 1.28 PRS_PLINK_0.00398107170553497 FALSE 962.1 Adrenal cortical steroids causing adverse effects in therapeutic use Both 72 400 18 injuries & poisonings gray50 400, 72 100, 19 100, 19 100, 16 100, 18 -0.0386 0.13 0.767 0.115 0.962 0.745 1.24 -0.0235 0.359 0.948 0.02329 0.977 0.484 1.97 -0.128 0.379 0.736 0.133 0.88 0.419 1.85 -0.00232 0.37 0.995 0.00218 0.998 0.483 2.06 PRS_PLINK_0.00398107170553497 FALSE 962.2 Insulins and antidiabetic agents causing adverse effects in therapeutic use Both 17 120 18 injuries & poisonings gray50 120, 17 30, 6 30, 3 30, 7 30, 1 -0.478 0.291 0.101 0.9965 0.62 0.35 1.1 -0.0422 0.78 0.957 0.01915 0.959 0.208 4.42 0.535 0.683 0.434 0.3629 1.71 0.448 6.51 -0.79 0.897 0.379 0.4218 0.454 0.0782 2.63 PRS_PLINK_0.00398107170553497 TRUE 962.3 Hormones and synthetic substitutes causing adverse effects in therapeutic use Both 87 521 18 injuries & poisonings gray50 521, 87 131, 29 130, 22 130, 15 130, 21 -0.228 0.119 0.0553 1.257 0.796 0.631 1.01 -0.306 0.312 0.327 0.4853 0.736 0.399 1.36 -0.698 0.346 0.0437 1.359 0.498 0.253 0.981 -0.29 0.313 0.355 0.45 0.749 0.405 1.38 PRS_PLINK_0.00398107170553497 FALSE 963 Poisoning by primarily systemic agents Both 388 2640 18 injuries & poisonings gray50 2640, 388 659, 113 660, 88 660, 90 660, 97 -0.0537 0.0558 0.336 0.4738 0.948 0.85 1.06 -0.251 0.154 0.102 0.9906 0.778 0.576 1.05 -0.216 0.156 0.167 0.7782 0.806 0.594 1.09 -0.167 0.154 0.28 0.5532 0.846 0.626 1.15 PRS_PLINK_0.00398107170553497 FALSE 963.1 Antineoplastic and immunosuppressive drugs causing adverse effects Both 375 2587 18 injuries & poisonings gray50 2587, 375 646, 109 647, 86 646, 83 647, 97 -0.0533 0.0566 0.347 0.46 0.948 0.848 1.06 -0.237 0.156 0.127 0.8949 0.789 0.581 1.07 -0.26 0.16 0.103 0.9854 0.771 0.563 1.05 -0.131 0.156 0.4 0.3977 0.877 0.646 1.19 PRS_PLINK_0.00398107170553497 FALSE 964 Poisoning by agents primarily affecting blood constituents Both 101 714 18 injuries & poisonings gray50 714, 101 179, 27 178, 28 178, 19 179, 27 -0.0762 0.105 0.468 0.3295 0.927 0.754 1.14 0.0238 0.292 0.935 0.02909 1.02 0.578 1.82 -0.296 0.318 0.352 0.4538 0.744 0.399 1.39 -0.0146 0.305 0.962 0.01692 0.985 0.542 1.79 PRS_PLINK_0.00398107170553497 FALSE 964.1 Anticoagulants causing adverse effects Both 91 675 18 injuries & poisonings gray50 675, 91 169, 25 169, 25 168, 17 169, 24 -0.0636 0.112 0.569 0.2449 0.938 0.754 1.17 -0.0498 0.309 0.872 0.05953 0.951 0.519 1.74 -0.356 0.338 0.292 0.5347 0.701 0.362 1.36 -0.0755 0.325 0.816 0.08825 0.927 0.491 1.75 PRS_PLINK_0.00398107170553497 FALSE 965 Poisoning by analgesics, antipyretics, and antirheumatics Both 134 970 18 injuries & poisonings gray50 970, 134 243, 21 242, 36 242, 40 243, 37 0.169 0.0964 0.0789 1.103 1.18 0.981 1.43 0.537 0.286 0.0602 1.221 1.71 0.977 2.99 0.628 0.282 0.0258 1.589 1.87 1.08 3.26 0.479 0.289 0.0976 1.011 1.61 0.916 2.84 PRS_PLINK_0.00398107170553497 FALSE 965.1 Opiates and related narcotics causing adverse effects in therapeutic use Both 192 1639 18 injuries & poisonings gray50 1639, 192 410, 46 410, 54 409, 40 410, 52 0.0177 0.0785 0.822 0.08531 1.02 0.873 1.19 0.0752 0.214 0.725 0.1395 1.08 0.709 1.64 -0.172 0.231 0.456 0.341 0.842 0.535 1.32 0.124 0.219 0.572 0.2429 1.13 0.737 1.74 PRS_PLINK_0.00398107170553497 FALSE 965.3 Salicylates causing adverse effects in therapeutic use Both 19 118 18 injuries & poisonings gray50 118, 19 30, 0 29, 5 29, 11 30, 3 0.401 0.264 0.129 0.8901 1.49 0.89 2.51 1.91 1.12 0.0881 1.055 6.74 0.752 60.3 2.9 1.26 0.0209 1.68 18.3 1.55 215 1.16 1.09 0.289 0.5385 3.18 0.374 27 PRS_PLINK_0.00398107170553497 TRUE 966 Poisoning by anticonvulsants and anti-Parkinsonism drugs Both 19 114 18 injuries & poisonings gray50 114, 19 29, 10 28, 4 28, 2 29, 3 -0.298 0.249 0.231 0.6359 0.742 0.456 1.21 -0.745 0.649 0.251 0.6006 0.475 0.133 1.69 -1.5 0.807 0.0639 1.194 0.224 0.0461 1.09 -0.94 0.648 0.147 0.833 0.391 0.11 1.39 PRS_PLINK_0.00398107170553497 TRUE 967 Adverse effects of sedatives or other central nervous system depressants and anesthetics Both 188 1439 18 injuries & poisonings gray50 1439, 188 360, 53 360, 50 359, 40 360, 45 -0.0668 0.0813 0.411 0.3861 0.935 0.798 1.1 -0.0577 0.213 0.786 0.1044 0.944 0.622 1.43 -0.289 0.225 0.2 0.6994 0.749 0.482 1.16 -0.16 0.223 0.473 0.3252 0.852 0.551 1.32 PRS_PLINK_0.00398107170553497 FALSE 969 Poisoning by psychotropic agents Both 45 285 18 injuries & poisonings gray50 285, 45 72, 12 71, 19 71, 5 71, 9 -0.213 0.167 0.202 0.6946 0.808 0.583 1.12 0.546 0.412 0.186 0.7314 1.73 0.769 3.87 -0.795 0.54 0.141 0.8508 0.452 0.157 1.3 -0.239 0.462 0.605 0.218 0.787 0.318 1.95 PRS_PLINK_0.00398107170553497 TRUE 971 Poisoning by drugs primarily affecting the autonomic nervous system Both 16 61 18 injuries & poisonings gray50 61, 16 16, 6 15, 3 15, 4 15, 3 -0.0937 0.294 0.75 0.1251 0.911 0.512 1.62 -0.571 0.855 0.504 0.2972 0.565 0.106 3.02 -0.633 0.901 0.482 0.3166 0.531 0.0908 3.1 -0.0855 0.898 0.924 0.03426 0.918 0.158 5.34 PRS_PLINK_0.00398107170553497 TRUE 972 Poisoning by agents primarily affecting the cardiovascular system Both 58 283 18 injuries & poisonings gray50 283, 58 71, 13 71, 11 70, 15 71, 19 0.176 0.149 0.238 0.6233 1.19 0.89 1.6 -0.021 0.442 0.962 0.01675 0.979 0.412 2.33 0.068 0.433 0.875 0.05791 1.07 0.458 2.5 0.318 0.437 0.467 0.3308 1.37 0.584 3.24 PRS_PLINK_0.00398107170553497 FALSE 972.1 Cardiac rhythm regulators causing adverse effects in therapeutic use Both 14 69 18 injuries & poisonings gray50 69, 14 18, 3 17, 2 17, 7 17, 2 -0.0809 0.338 0.811 0.09107 0.922 0.475 1.79 0.0641 0.869 0.941 0.02631 1.07 0.194 5.86 0.581 1.01 0.567 0.2463 1.79 0.245 13.1 0.276 0.903 0.76 0.1193 1.32 0.225 7.73 PRS_PLINK_0.00398107170553497 TRUE 972.6 Antihypertensive agents causing adverse effects Both 28 113 18 injuries & poisonings gray50 113, 28 29, 5 28, 8 28, 6 28, 9 0.107 0.205 0.603 0.2198 1.11 0.744 1.66 0.448 0.621 0.471 0.3273 1.57 0.463 5.29 0.275 0.748 0.714 0.1465 1.32 0.304 5.71 0.784 0.701 0.263 0.5797 2.19 0.555 8.65 PRS_PLINK_0.00398107170553497 TRUE 974 Poisoning by water, mineral, and uric acid metabolism drugs Both 15 126 18 injuries & poisonings gray50 126, 15 32, 5 31, 4 31, 4 32, 2 -0.311 0.283 0.272 0.5653 0.732 0.42 1.28 -0.0562 0.684 0.935 0.02942 0.945 0.247 3.61 -0.413 0.71 0.561 0.2512 0.661 0.164 2.66 -0.628 0.76 0.409 0.3888 0.533 0.12 2.37 PRS_PLINK_0.00398107170553497 TRUE 975 Poisoning by agents primarily acting on the smooth and skeletal muscles and respiratory system Both 20 78 18 injuries & poisonings gray50 78, 20 20, 4 19, 9 19, 1 20, 6 0.0803 0.309 0.795 0.0995 1.08 0.591 1.99 0.327 0.72 0.65 0.1873 1.39 0.338 5.69 -0.716 0.913 0.433 0.3639 0.489 0.0816 2.92 -0.0675 0.827 0.935 0.02924 0.935 0.185 4.72 PRS_PLINK_0.00398107170553497 TRUE 976 Poisoning by agents primarily affecting skin & mucous membrane, ophthalmological, otorhinolaryngological, & dental drugs Both 10 93 18 injuries & poisonings gray50 93, 10 24, 3 23, 2 23, 2 23, 3 -0.0406 0.293 0.89 0.0506 0.96 0.54 1.71 0.0827 0.953 0.931 0.03112 1.09 0.168 7.04 -0.574 0.887 0.517 0.2864 0.563 0.099 3.2 0.119 0.796 0.881 0.05515 1.13 0.237 5.36 PRS_PLINK_0.00398107170553497 TRUE 977 Personal history of allergy to medicinal agents Both 255 1865 18 injuries & poisonings gray50 1865, 255 467, 54 466, 69 466, 70 466, 62 0.0585 0.0693 0.398 0.4001 1.06 0.926 1.21 0.246 0.194 0.206 0.6854 1.28 0.873 1.87 0.225 0.195 0.248 0.6058 1.25 0.855 1.83 0.147 0.202 0.468 0.3294 1.16 0.779 1.72 PRS_PLINK_0.00398107170553497 FALSE 979 Adverse drug events and drug allergies Both 589 3409 18 injuries & poisonings gray50 3409, 589 852, 135 852, 166 852, 141 852, 147 0.0488 0.0456 0.285 0.5458 1.05 0.96 1.15 0.205 0.127 0.106 0.9748 1.23 0.957 1.57 0.0612 0.133 0.645 0.1901 1.06 0.819 1.38 0.0659 0.133 0.62 0.2073 1.07 0.823 1.39 PRS_PLINK_0.00398107170553497 FALSE 980 Encounter for long-term (current) use of antibiotics Both 150 1341 1 infectious diseases blue 1341, 150 336, 41 335, 30 335, 33 335, 46 -0.0145 0.0879 0.869 0.06076 0.986 0.83 1.17 -0.296 0.251 0.239 0.6222 0.744 0.454 1.22 -0.196 0.249 0.43 0.3666 0.822 0.504 1.34 0.0565 0.237 0.811 0.09082 1.06 0.665 1.68 PRS_PLINK_0.00398107170553497 FALSE 985 Toxic effect of other metals Both 9 67 18 injuries & poisonings gray50 67, 9 17, 2 17, 2 16, 4 17, 1 -0.125 0.406 0.758 0.1205 0.882 0.398 1.96 -1.25 1.33 0.349 0.4569 0.287 0.021 3.92 -0.0669 0.893 0.94 0.02674 0.935 0.162 5.38 -0.628 1.2 0.602 0.2203 0.534 0.0504 5.65 PRS_PLINK_0.00398107170553497 TRUE 989 Toxic effect of other substances, chiefly nonmedicinal as to source Both 31 154 18 injuries & poisonings gray50 154, 31 39, 10 38, 10 38, 5 39, 6 -0.188 0.236 0.425 0.372 0.829 0.522 1.31 -0.0873 0.535 0.87 0.0603 0.916 0.321 2.61 -0.326 0.594 0.583 0.2341 0.722 0.225 2.31 -0.616 0.576 0.285 0.5452 0.54 0.175 1.67 PRS_PLINK_0.00398107170553497 TRUE 990 Effects radiation NOS Both 397 3485 18 injuries & poisonings gray50 3485, 397 871, 102 871, 100 871, 94 871, 101 -0.00339 0.0546 0.951 0.02203 0.997 0.896 1.11 -0.0132 0.15 0.93 0.03171 0.987 0.736 1.32 -0.0648 0.155 0.675 0.1704 0.937 0.692 1.27 -0.0209 0.154 0.892 0.04959 0.979 0.724 1.32 PRS_PLINK_0.00398107170553497 FALSE 994 Sepsis and SIRS Both 240 2205 18 injuries & poisonings gray50 2205, 240 552, 70 551, 65 551, 49 551, 56 -0.102 0.0694 0.143 0.8455 0.903 0.788 1.03 -0.0811 0.183 0.657 0.1825 0.922 0.645 1.32 -0.352 0.197 0.075 1.125 0.704 0.478 1.04 -0.278 0.194 0.152 0.8176 0.757 0.517 1.11 PRS_PLINK_0.00398107170553497 FALSE 994.1 Systemic inflammatory response syndrome (SIRS) Both 38 309 18 injuries & poisonings gray50 309, 38 78, 9 77, 6 77, 8 77, 15 0.203 0.179 0.258 0.5889 1.23 0.862 1.74 -0.274 0.543 0.614 0.2121 0.76 0.262 2.2 0.114 0.497 0.818 0.08702 1.12 0.423 2.97 0.63 0.462 0.173 0.763 1.88 0.759 4.64 PRS_PLINK_0.00398107170553497 TRUE 994.2 Sepsis Both 225 2086 18 injuries & poisonings gray50 2086, 225 522, 64 521, 63 521, 48 522, 50 -0.0984 0.0712 0.167 0.7776 0.906 0.788 1.04 -0.0252 0.188 0.893 0.04891 0.975 0.675 1.41 -0.304 0.202 0.133 0.8773 0.738 0.497 1.1 -0.29 0.204 0.155 0.8107 0.748 0.502 1.12 PRS_PLINK_0.00398107170553497 FALSE 994.21 Septic shock Both 48 603 18 injuries & poisonings gray50 603, 48 151, 22 151, 10 150, 4 151, 12 -0.266 0.148 0.0734 1.134 0.767 0.573 1.03 -0.835 0.397 0.0353 1.452 0.434 0.2 0.944 -1.45 0.527 0.00608 2.216 0.235 0.0838 0.662 -0.536 0.384 0.163 0.7882 0.585 0.276 1.24 PRS_PLINK_0.00398107170553497 TRUE