phewas_code phewas_string sex MatchedCases MatchedControls groupnum group color N N_Q1 N_Q2 N_Q3 N_Q4 PRS_BETA PRS_SEBETA PRS_P PRS_LOG10P PRS_OR PRS_CI1 PRS_CI2 Q1Q2_BETA Q1Q2_SEBETA Q1Q2_P Q1Q2_LOG10P Q1Q2_OR Q1Q2_CI1 Q1Q2_CI2 Q1Q3_BETA Q1Q3_SEBETA Q1Q3_P Q1Q3_LOG10P Q1Q3_OR Q1Q3_CI1 Q1Q3_CI2 Q1Q4_BETA Q1Q4_SEBETA Q1Q4_P Q1Q4_LOG10P Q1Q4_OR Q1Q4_CI1 Q1Q4_CI2 predictor 008 Intestinal infection Both 1113 14731 1 infectious diseases blue 14731, 1113 3683, 288 3683, 290 3682, 281 3683, 253 -0.0496 0.0309 0.109 0.9645 0.952 0.896 1.01 0.00497 0.0863 0.954 0.02041 1 0.849 1.19 -0.0216 0.0869 0.804 0.09492 0.979 0.825 1.16 -0.121 0.0892 0.176 0.7537 0.886 0.744 1.06 PRS_PLINK_1e.04 008.5 Bacterial enteritis Both 390 6068 1 infectious diseases blue 6068, 390 1517, 98 1517, 107 1517, 106 1517, 79 -0.0852 0.0524 0.104 0.9844 0.918 0.829 1.02 0.0873 0.143 0.543 0.2655 1.09 0.824 1.45 0.0732 0.144 0.611 0.214 1.08 0.811 1.43 -0.218 0.155 0.16 0.7963 0.804 0.594 1.09 PRS_PLINK_1e.04 008.52 Intestinal infection due to C. difficile Both 290 4692 1 infectious diseases blue 4692, 290 1173, 76 1173, 81 1173, 78 1173, 55 -0.111 0.0599 0.0629 1.201 0.895 0.796 1.01 0.0598 0.163 0.714 0.1462 1.06 0.771 1.46 0.00347 0.165 0.983 0.007354 1 0.726 1.39 -0.326 0.18 0.0696 1.158 0.722 0.508 1.03 PRS_PLINK_1e.04 008.6 Viral Enteritis Both 278 4076 1 infectious diseases blue 4076, 278 1019, 79 1019, 70 1019, 57 1019, 71 -0.0826 0.0623 0.185 0.7338 0.921 0.815 1.04 -0.101 0.168 0.547 0.2617 0.904 0.65 1.26 -0.342 0.177 0.0538 1.269 0.71 0.502 1.01 -0.113 0.168 0.501 0.3005 0.893 0.643 1.24 PRS_PLINK_1e.04 010 Tuberculosis Both 98 1131 1 infectious diseases blue 1131, 98 283, 22 283, 30 282, 21 283, 25 0.0855 0.102 0.4 0.3978 1.09 0.893 1.33 0.313 0.287 0.275 0.5608 1.37 0.78 2.4 -0.0091 0.306 0.976 0.01043 0.991 0.544 1.8 0.1 0.294 0.733 0.135 1.11 0.621 1.97 PRS_PLINK_1e.04 031 Diseases due to other mycobacteria Both 39 431 1 infectious diseases blue 431, 39 108, 8 108, 10 107, 10 108, 11 0.0923 0.166 0.577 0.2385 1.1 0.793 1.52 0.371 0.479 0.438 0.3582 1.45 0.567 3.71 0.0709 0.476 0.881 0.05482 1.07 0.423 2.73 0.524 0.477 0.273 0.564 1.69 0.662 4.3 PRS_PLINK_1e.04 038 Septicemia Both 605 10999 1 infectious diseases blue 10999, 605 2750, 144 2750, 161 2749, 156 2750, 144 0.0051 0.0419 0.903 0.04426 1.01 0.926 1.09 0.111 0.117 0.346 0.4614 1.12 0.888 1.41 0.0869 0.118 0.462 0.3356 1.09 0.865 1.37 -0.000533 0.12 0.996 0.001535 0.999 0.789 1.27 PRS_PLINK_1e.04 038.1 Gram negative septicemia Both 108 2326 1 infectious diseases blue 2326, 108 582, 23 581, 32 581, 28 582, 25 0.0853 0.0959 0.373 0.4278 1.09 0.903 1.31 0.364 0.272 0.18 0.744 1.44 0.845 2.45 0.193 0.278 0.488 0.3118 1.21 0.703 2.09 0.0962 0.285 0.735 0.1334 1.1 0.63 1.92 PRS_PLINK_1e.04 038.2 Gram positive septicemia Both 46 1037 1 infectious diseases blue 1037, 46 260, 11 259, 11 259, 10 259, 14 0.0822 0.149 0.58 0.2365 1.09 0.811 1.45 -0.023 0.404 0.955 0.02014 0.977 0.443 2.16 -0.123 0.415 0.767 0.1155 0.884 0.392 1.99 0.168 0.388 0.665 0.1775 1.18 0.553 2.53 PRS_PLINK_1e.04 038.3 Bacteremia Both 234 5167 1 infectious diseases blue 5167, 234 1292, 52 1292, 60 1291, 64 1292, 58 0.0136 0.0665 0.838 0.07677 1.01 0.89 1.15 0.131 0.191 0.493 0.3072 1.14 0.784 1.66 0.201 0.188 0.287 0.5424 1.22 0.845 1.77 0.127 0.193 0.511 0.292 1.14 0.778 1.66 PRS_PLINK_1e.04 041 Bacterial infection NOS Both 1952 20195 1 infectious diseases blue 20195, 1952 5049, 536 5049, 478 5048, 502 5049, 435 -0.0616 0.0237 0.00931 2.031 0.94 0.898 0.985 -0.117 0.066 0.0769 1.114 0.89 0.782 1.01 -0.073 0.0653 0.263 0.5796 0.93 0.818 1.06 -0.212 0.0676 0.00166 2.78 0.809 0.708 0.923 PRS_PLINK_1e.04 041.1 Staphylococcus infections Both 477 8209 1 infectious diseases blue 8209, 477 2053, 122 2052, 131 2052, 109 2052, 114 -0.0656 0.046 0.154 0.8117 0.937 0.856 1.02 0.0608 0.129 0.637 0.1958 1.06 0.825 1.37 -0.118 0.134 0.379 0.4216 0.888 0.683 1.16 -0.0672 0.133 0.614 0.2116 0.935 0.72 1.21 PRS_PLINK_1e.04 041.11 Methicillin sensitive Staphylococcus aureus Both 238 4400 1 infectious diseases blue 4400, 238 1100, 62 1100, 65 1100, 54 1100, 56 -0.0727 0.0657 0.269 0.5706 0.93 0.818 1.06 0.0431 0.18 0.811 0.09093 1.04 0.733 1.49 -0.148 0.188 0.43 0.3661 0.862 0.596 1.25 -0.115 0.187 0.539 0.2687 0.891 0.618 1.29 PRS_PLINK_1e.04 041.12 Methicillin resistant Staphylococcus aureus Both 217 3770 1 infectious diseases blue 3770, 217 943, 59 942, 56 942, 49 943, 53 -0.0703 0.0677 0.299 0.5248 0.932 0.816 1.06 -0.0479 0.19 0.801 0.0966 0.953 0.657 1.38 -0.193 0.196 0.324 0.4892 0.824 0.562 1.21 -0.0961 0.192 0.617 0.2098 0.908 0.623 1.32 PRS_PLINK_1e.04 041.2 Streptococcus infection Both 469 7374 1 infectious diseases blue 7374, 469 1844, 125 1843, 112 1843, 115 1844, 117 -0.0373 0.0472 0.429 0.3673 0.963 0.878 1.06 -0.119 0.133 0.371 0.4304 0.888 0.684 1.15 -0.0857 0.132 0.518 0.2859 0.918 0.708 1.19 -0.0632 0.132 0.633 0.1988 0.939 0.725 1.22 PRS_PLINK_1e.04 041.21 Rheumatic fever / chorea Both 83 1046 1 infectious diseases blue 1046, 83 262, 23 261, 20 261, 22 262, 18 -0.0529 0.108 0.624 0.2047 0.948 0.768 1.17 -0.113 0.306 0.711 0.1483 0.893 0.49 1.63 -0.0292 0.3 0.922 0.03506 0.971 0.54 1.75 -0.241 0.315 0.444 0.3529 0.786 0.424 1.46 PRS_PLINK_1e.04 041.4 E. coli Both 275 5187 1 infectious diseases blue 5187, 275 1297, 74 1297, 69 1296, 72 1297, 59 -0.077 0.0613 0.209 0.6797 0.926 0.821 1.04 -0.0815 0.17 0.631 0.1998 0.922 0.661 1.29 -0.035 0.168 0.835 0.07835 0.966 0.695 1.34 -0.232 0.177 0.19 0.7223 0.793 0.561 1.12 PRS_PLINK_1e.04 041.8 H. pylori Both 118 1278 1 infectious diseases blue 1278, 118 320, 36 319, 28 319, 29 320, 25 -0.124 0.0937 0.186 0.7303 0.883 0.735 1.06 -0.245 0.258 0.342 0.4662 0.783 0.473 1.3 -0.233 0.257 0.365 0.438 0.792 0.479 1.31 -0.388 0.267 0.146 0.8343 0.678 0.401 1.15 PRS_PLINK_1e.04 041.9 Infection with drug-resistant microorganisms Both 84 1772 1 infectious diseases blue 1772, 84 443, 26 443, 26 443, 21 443, 11 -0.196 0.102 0.0564 1.249 0.822 0.673 1.01 0.0128 0.277 0.963 0.01632 1.01 0.589 1.74 -0.188 0.292 0.519 0.285 0.828 0.468 1.47 -0.798 0.345 0.0209 1.68 0.45 0.229 0.886 PRS_PLINK_1e.04 053 Herpes zoster Both 534 6543 1 infectious diseases blue 6543, 534 1636, 141 1636, 143 1635, 122 1636, 128 -0.0624 0.0448 0.163 0.7873 0.94 0.861 1.03 0.0154 0.123 0.901 0.04544 1.02 0.798 1.29 -0.138 0.128 0.28 0.5536 0.871 0.678 1.12 -0.098 0.126 0.438 0.3583 0.907 0.708 1.16 PRS_PLINK_1e.04 053.1 Herpes zoster with nervous system complications Both 58 860 1 infectious diseases blue 860, 58 215, 12 215, 14 215, 11 215, 21 0.129 0.137 0.345 0.4624 1.14 0.87 1.49 0.0983 0.384 0.798 0.09811 1.1 0.52 2.34 -0.0476 0.393 0.903 0.0441 0.953 0.442 2.06 0.548 0.358 0.125 0.9019 1.73 0.858 3.49 PRS_PLINK_1e.04 054 Herpes simplex Both 839 8495 1 infectious diseases blue 8495, 839 2124, 218 2124, 225 2123, 204 2124, 192 -0.0381 0.0362 0.292 0.5349 0.963 0.897 1.03 0.0349 0.0998 0.727 0.1386 1.04 0.852 1.26 -0.0739 0.102 0.469 0.3292 0.929 0.761 1.13 -0.13 0.103 0.207 0.6835 0.878 0.717 1.07 PRS_PLINK_1e.04 070 Viral hepatitis Both 286 3678 1 infectious diseases blue 3678, 286 920, 80 919, 72 919, 73 920, 61 -0.107 0.0614 0.0812 1.09 0.899 0.797 1.01 -0.11 0.168 0.513 0.2897 0.896 0.645 1.24 -0.102 0.167 0.541 0.2667 0.903 0.651 1.25 -0.274 0.175 0.116 0.9345 0.76 0.54 1.07 PRS_PLINK_1e.04 070.1 Viral hepatitis A Both 29 314 1 infectious diseases blue 314, 29 79, 8 78, 10 78, 6 79, 5 -0.191 0.18 0.289 0.5388 0.826 0.58 1.18 0.284 0.479 0.554 0.2565 1.33 0.519 3.4 -0.227 0.542 0.676 0.1703 0.797 0.275 2.31 -0.327 0.545 0.548 0.2609 0.721 0.248 2.1 PRS_PLINK_1e.04 070.2 Viral hepatitis B Both 72 948 1 infectious diseases blue 948, 72 237, 17 237, 16 237, 17 237, 22 0.0941 0.118 0.426 0.3708 1.1 0.871 1.39 -0.0561 0.346 0.871 0.06 0.945 0.48 1.86 0.0277 0.346 0.936 0.0286 1.03 0.521 2.03 0.239 0.325 0.462 0.335 1.27 0.672 2.4 PRS_PLINK_1e.04 070.3 Viral hepatitis C Both 179 2354 1 infectious diseases blue 2354, 179 589, 55 588, 42 588, 45 589, 37 -0.121 0.078 0.121 0.9176 0.886 0.761 1.03 -0.26 0.21 0.216 0.6656 0.771 0.511 1.16 -0.209 0.208 0.314 0.5035 0.811 0.54 1.22 -0.4 0.218 0.0666 1.176 0.671 0.437 1.03 PRS_PLINK_1e.04 070.4 Chronic hepatitis Both 56 832 1 infectious diseases blue 832, 56 208, 14 208, 12 208, 19 208, 11 -0.0469 0.134 0.727 0.1386 0.954 0.733 1.24 -0.109 0.395 0.782 0.1068 0.896 0.413 1.94 0.256 0.349 0.463 0.334 1.29 0.651 2.56 -0.261 0.396 0.51 0.2923 0.77 0.354 1.68 PRS_PLINK_1e.04 070.9 Hepatitis NOS Both 381 4700 1 infectious diseases blue 4700, 381 1175, 92 1175, 106 1175, 91 1175, 92 -0.0216 0.0529 0.684 0.1651 0.979 0.882 1.09 0.142 0.147 0.337 0.4726 1.15 0.863 1.54 -0.000756 0.152 0.996 0.001724 0.999 0.741 1.35 0.00345 0.152 0.982 0.00791 1 0.744 1.35 PRS_PLINK_1e.04 071 Human immunodeficiency virus [HIV] disease Both 52 755 1 infectious diseases blue 755, 52 189, 16 189, 13 188, 13 189, 10 -0.0994 0.131 0.449 0.3478 0.905 0.7 1.17 -0.152 0.373 0.683 0.1653 0.859 0.414 1.78 -0.164 0.366 0.654 0.1845 0.849 0.415 1.74 -0.399 0.389 0.305 0.5158 0.671 0.313 1.44 PRS_PLINK_1e.04 071.1 HIV infection, symptomatic Both 45 595 1 infectious diseases blue 595, 45 149, 13 149, 9 148, 11 149, 12 -0.0438 0.149 0.769 0.1139 0.957 0.714 1.28 -0.253 0.426 0.552 0.2577 0.776 0.337 1.79 -0.129 0.403 0.748 0.126 0.879 0.399 1.94 -0.0895 0.394 0.82 0.08612 0.914 0.423 1.98 PRS_PLINK_1e.04 078 Viral warts & HPV Both 1755 15918 1 infectious diseases blue 15918, 1755 3980, 451 3979, 421 3979, 446 3980, 436 -0.0177 0.0251 0.482 0.317 0.982 0.935 1.03 -0.0739 0.0715 0.302 0.5203 0.929 0.807 1.07 -0.0168 0.0705 0.812 0.09063 0.983 0.856 1.13 -0.0368 0.0709 0.604 0.2193 0.964 0.839 1.11 PRS_PLINK_1e.04 079 Viral infection Both 3021 18189 1 infectious diseases blue 18189, 3021 4548, 744 4547, 785 4547, 756 4547, 736 -0.00853 0.0197 0.666 0.1768 0.992 0.954 1.03 0.0552 0.0558 0.322 0.4918 1.06 0.947 1.18 0.0111 0.0562 0.843 0.07397 1.01 0.906 1.13 -0.00866 0.0565 0.878 0.05639 0.991 0.887 1.11 PRS_PLINK_1e.04 079.1 Varicella infection Both 1689 15563 1 infectious diseases blue 15563, 1689 3891, 397 3891, 440 3890, 432 3891, 420 0.00847 0.0256 0.741 0.1303 1.01 0.959 1.06 0.109 0.0731 0.136 0.8653 1.11 0.966 1.29 0.0786 0.0732 0.283 0.5483 1.08 0.937 1.25 0.0555 0.0737 0.451 0.3454 1.06 0.915 1.22 PRS_PLINK_1e.04 079.2 Infectious mononucleosis Both 185 1947 1 infectious diseases blue 1947, 185 487, 54 487, 40 486, 47 487, 44 -0.0787 0.0763 0.302 0.5198 0.924 0.796 1.07 -0.285 0.218 0.19 0.7207 0.752 0.491 1.15 -0.163 0.208 0.433 0.3633 0.849 0.565 1.28 -0.237 0.212 0.262 0.581 0.789 0.521 1.19 PRS_PLINK_1e.04 079.9 Viremia, NOS Both 339 4630 1 infectious diseases blue 4630, 339 1158, 91 1157, 97 1157, 73 1158, 78 -0.0892 0.0559 0.111 0.9552 0.915 0.82 1.02 0.0778 0.152 0.608 0.2162 1.08 0.803 1.45 -0.206 0.161 0.201 0.6966 0.814 0.593 1.12 -0.129 0.159 0.416 0.3814 0.879 0.644 1.2 PRS_PLINK_1e.04 080 Postoperative infection Both 932 12596 1 infectious diseases blue 12596, 932 3149, 235 3149, 213 3149, 241 3149, 243 0.0257 0.0342 0.453 0.3438 1.03 0.959 1.1 -0.102 0.0977 0.294 0.5311 0.903 0.745 1.09 0.0257 0.0948 0.786 0.1044 1.03 0.852 1.24 0.0311 0.0946 0.742 0.1295 1.03 0.857 1.24 PRS_PLINK_1e.04 081 Infection/inflammation of internal prosthetic device; implant; and graft Both 512 7420 1 infectious diseases blue 7420, 512 1855, 117 1855, 135 1855, 140 1855, 120 0.0104 0.0463 0.822 0.08494 1.01 0.923 1.11 0.142 0.13 0.274 0.5624 1.15 0.894 1.49 0.182 0.129 0.158 0.8025 1.2 0.932 1.54 0.0206 0.133 0.877 0.05692 1.02 0.786 1.33 PRS_PLINK_1e.04 090 Sexually transmitted infections (not HIV or hepatitis) Both 488 5522 1 infectious diseases blue 5522, 488 1381, 125 1380, 117 1380, 129 1381, 117 -0.00736 0.0466 0.875 0.05823 0.993 0.906 1.09 -0.0602 0.133 0.651 0.1862 0.942 0.725 1.22 0.0398 0.131 0.761 0.1188 1.04 0.806 1.34 -0.0446 0.134 0.739 0.1314 0.956 0.736 1.24 PRS_PLINK_1e.04 110 Dermatophytosis / Dermatomycosis Both 1180 14384 1 infectious diseases blue 14384, 1180 3596, 306 3596, 268 3596, 299 3596, 307 0.00213 0.0303 0.944 0.0251 1 0.944 1.06 -0.119 0.087 0.171 0.768 0.888 0.748 1.05 -0.0187 0.0847 0.825 0.08345 0.981 0.831 1.16 0.0234 0.0843 0.781 0.1073 1.02 0.868 1.21 PRS_PLINK_1e.04 110.1 Dermatophytosis Both 1011 12666 1 infectious diseases blue 12666, 1011 3167, 264 3166, 224 3166, 255 3167, 268 0.00209 0.0325 0.949 0.02278 1 0.94 1.07 -0.157 0.0942 0.0957 1.019 0.855 0.711 1.03 -0.0334 0.0913 0.715 0.146 0.967 0.809 1.16 0.0345 0.0904 0.703 0.1533 1.04 0.867 1.24 PRS_PLINK_1e.04 110.11 Dermatophytosis of nail Both 541 6998 1 infectious diseases blue 6998, 541 1750, 141 1749, 129 1749, 137 1750, 134 0.00419 0.0443 0.925 0.03402 1 0.921 1.1 -0.0896 0.126 0.477 0.3212 0.914 0.714 1.17 -0.0232 0.124 0.852 0.06965 0.977 0.766 1.25 -0.0321 0.125 0.797 0.09844 0.968 0.758 1.24 PRS_PLINK_1e.04 110.12 Althete's foot Both 248 3449 1 infectious diseases blue 3449, 248 863, 64 862, 59 862, 63 862, 62 0.0157 0.0649 0.809 0.09186 1.02 0.894 1.15 -0.0732 0.185 0.692 0.1599 0.929 0.647 1.34 -0.0117 0.182 0.949 0.02276 0.988 0.692 1.41 -0.041 0.182 0.822 0.08499 0.96 0.671 1.37 PRS_PLINK_1e.04 110.13 Dermatophytosis of the body Both 288 3863 1 infectious diseases blue 3863, 288 966, 74 966, 51 965, 73 966, 90 0.0364 0.0599 0.544 0.2645 1.04 0.922 1.17 -0.342 0.185 0.0651 1.186 0.711 0.494 1.02 0.00442 0.17 0.979 0.009111 1 0.72 1.4 0.241 0.163 0.14 0.8538 1.27 0.924 1.75 PRS_PLINK_1e.04 110.2 Dermatomycoses Both 208 2289 1 infectious diseases blue 2289, 208 573, 51 572, 45 572, 61 572, 51 0.00322 0.0724 0.964 0.01571 1 0.871 1.16 -0.101 0.211 0.631 0.2002 0.904 0.598 1.37 0.178 0.197 0.365 0.4382 1.2 0.813 1.76 0.0201 0.205 0.922 0.03521 1.02 0.682 1.53 PRS_PLINK_1e.04 112 Candidiasis Both 1517 15933 1 infectious diseases blue 15933, 1517 3984, 391 3983, 368 3983, 367 3983, 390 -0.00202 0.027 0.94 0.02667 0.998 0.947 1.05 -0.0658 0.076 0.387 0.4126 0.936 0.807 1.09 -0.0709 0.076 0.351 0.4546 0.932 0.803 1.08 -0.0018 0.0752 0.981 0.008395 0.998 0.861 1.16 PRS_PLINK_1e.04 112.3 Candidiasis of skin and nails Both 168 3228 1 infectious diseases blue 3228, 168 807, 48 807, 49 807, 40 807, 31 -0.154 0.0796 0.0526 1.279 0.857 0.733 1 0.00267 0.206 0.99 0.004528 1 0.67 1.5 -0.182 0.215 0.398 0.4001 0.834 0.546 1.27 -0.432 0.229 0.0594 1.226 0.649 0.414 1.02 PRS_PLINK_1e.04 117 Mycoses Both 231 3012 1 infectious diseases blue 3012, 231 753, 57 753, 71 753, 48 753, 55 -0.0551 0.0676 0.415 0.3821 0.946 0.829 1.08 0.222 0.183 0.226 0.6458 1.25 0.872 1.79 -0.162 0.2 0.416 0.3813 0.85 0.575 1.26 -0.0234 0.193 0.904 0.04393 0.977 0.669 1.43 PRS_PLINK_1e.04 117.1 Histoplasmosis Both 27 340 1 infectious diseases blue 340, 27 85, 9 85, 6 85, 1 85, 11 0.0244 0.199 0.902 0.04458 1.02 0.693 1.51 -0.83 0.568 0.144 0.8411 0.436 0.143 1.33 -1.98 0.82 0.0156 1.807 0.138 0.0275 0.686 0.129 0.466 0.781 0.1074 1.14 0.457 2.83 PRS_PLINK_1e.04 117.4 Aspergillosis Both 43 663 1 infectious diseases blue 663, 43 166, 9 166, 15 165, 8 166, 11 -0.0715 0.152 0.638 0.1952 0.931 0.691 1.25 0.487 0.411 0.237 0.626 1.63 0.727 3.64 -0.146 0.465 0.753 0.1234 0.864 0.348 2.15 0.23 0.438 0.6 0.2222 1.26 0.533 2.97 PRS_PLINK_1e.04 130 Spirochetal infection Both 79 821 1 infectious diseases blue 821, 79 206, 15 205, 16 205, 23 205, 25 0.179 0.117 0.128 0.8935 1.2 0.95 1.5 0.11 0.357 0.757 0.1209 1.12 0.555 2.25 0.415 0.333 0.212 0.6728 1.51 0.789 2.91 0.505 0.336 0.133 0.8774 1.66 0.858 3.2 PRS_PLINK_1e.04 130.1 Lyme disease Both 59 588 1 infectious diseases blue 588, 59 147, 11 147, 12 147, 15 147, 21 0.242 0.144 0.092 1.036 1.27 0.961 1.69 0.0883 0.407 0.828 0.0819 1.09 0.492 2.42 0.317 0.393 0.419 0.3774 1.37 0.636 2.97 0.6 0.38 0.114 0.9431 1.82 0.866 3.83 PRS_PLINK_1e.04 131 Protozoan infection Both 39 406 1 infectious diseases blue 406, 39 101, 11 101, 9 101, 9 102, 10 -0.0779 0.168 0.642 0.1925 0.925 0.666 1.28 -0.244 0.454 0.591 0.2284 0.783 0.322 1.91 -0.163 0.446 0.714 0.1461 0.849 0.354 2.04 -0.163 0.438 0.71 0.1486 0.85 0.361 2 PRS_PLINK_1e.04 132 Infestation (lice, mites) Both 95 1045 1 infectious diseases blue 1045, 95 262, 21 261, 21 261, 23 261, 30 0.173 0.106 0.101 0.9948 1.19 0.967 1.46 0.0253 0.311 0.935 0.02912 1.03 0.557 1.89 0.0799 0.311 0.797 0.09842 1.08 0.589 1.99 0.323 0.289 0.263 0.5797 1.38 0.784 2.43 PRS_PLINK_1e.04 134 Helminthiases Both 29 419 1 infectious diseases blue 419, 29 105, 12 105, 7 104, 5 105, 5 -0.345 0.177 0.0514 1.289 0.708 0.5 1 -0.561 0.464 0.226 0.6453 0.571 0.23 1.42 -0.977 0.517 0.0587 1.232 0.376 0.137 1.04 -0.815 0.501 0.104 0.9826 0.443 0.166 1.18 PRS_PLINK_1e.04 134.1 Intestinal helminthiases Both 21 259 1 infectious diseases blue 259, 21 65, 9 65, 7 64, 4 65, 1 -0.415 0.194 0.0323 1.491 0.661 0.452 0.966 -0.162 0.501 0.746 0.1272 0.85 0.319 2.27 -0.729 0.58 0.209 0.6804 0.482 0.155 1.5 -1.73 0.791 0.0283 1.548 0.176 0.0374 0.832 PRS_PLINK_1e.04 136 Other infectious and parasitic diseases Both 1311 15873 1 infectious diseases blue 15873, 1311 3968, 330 3968, 328 3968, 346 3968, 307 -0.0234 0.0288 0.418 0.3786 0.977 0.923 1.03 -0.00999 0.081 0.902 0.04485 0.99 0.845 1.16 0.045 0.08 0.574 0.2411 1.05 0.894 1.22 -0.0678 0.0823 0.41 0.3874 0.934 0.795 1.1 PRS_PLINK_1e.04 145 Cancer of mouth Both 600 5428 2 neoplasms darkcyan 5428, 600 1357, 158 1357, 147 1357, 159 1357, 136 -0.0396 0.0425 0.351 0.4542 0.961 0.884 1.04 -0.0733 0.12 0.543 0.2654 0.929 0.734 1.18 0.0157 0.118 0.894 0.04843 1.02 0.805 1.28 -0.152 0.123 0.217 0.663 0.859 0.675 1.09 PRS_PLINK_1e.04 145.1 Cancer of lip Both 28 265 2 neoplasms darkcyan 265, 28 67, 9 66, 9 66, 4 66, 6 -0.183 0.205 0.373 0.4281 0.833 0.557 1.25 -0.0546 0.489 0.911 0.0404 0.947 0.363 2.47 -0.597 0.609 0.327 0.4855 0.551 0.167 1.82 -0.266 0.532 0.617 0.2095 0.767 0.27 2.18 PRS_PLINK_1e.04 145.2 Cancer of tongue Both 272 2391 2 neoplasms darkcyan 2391, 272 598, 65 598, 72 597, 67 598, 68 -0.0101 0.0638 0.874 0.05844 0.99 0.874 1.12 0.0783 0.18 0.663 0.1783 1.08 0.76 1.54 0.0416 0.182 0.819 0.08654 1.04 0.73 1.49 0.024 0.182 0.895 0.0482 1.02 0.717 1.46 PRS_PLINK_1e.04 145.3 Cancer of major salivary glands Both 153 1398 2 neoplasms darkcyan 1398, 153 350, 42 349, 36 349, 40 350, 35 -0.07 0.0847 0.409 0.3885 0.932 0.79 1.1 -0.138 0.236 0.558 0.2533 0.871 0.549 1.38 -0.0512 0.23 0.824 0.08417 0.95 0.605 1.49 -0.179 0.239 0.453 0.3444 0.836 0.524 1.33 PRS_PLINK_1e.04 145.4 Cancer of the gums Both 51 553 2 neoplasms darkcyan 553, 51 139, 13 138, 13 138, 13 138, 12 -0.0197 0.142 0.889 0.051 0.98 0.743 1.29 -0.0805 0.401 0.841 0.07528 0.923 0.42 2.02 0.0141 0.394 0.972 0.01255 1.01 0.469 2.19 -0.089 0.402 0.825 0.08372 0.915 0.416 2.01 PRS_PLINK_1e.04 145.5 Cancer of the mouth floor Both 74 767 2 neoplasms darkcyan 767, 74 192, 18 192, 20 191, 20 192, 16 -0.047 0.124 0.705 0.1516 0.954 0.748 1.22 0.144 0.336 0.667 0.1759 1.16 0.598 2.23 0.109 0.331 0.743 0.1292 1.11 0.583 2.13 -0.152 0.349 0.663 0.1785 0.859 0.434 1.7 PRS_PLINK_1e.04 149 Cancer of larynx, pharynx, nasal cavities Both 546 4749 2 neoplasms darkcyan 4749, 546 1188, 133 1187, 135 1187, 152 1187, 126 -0.0135 0.0446 0.761 0.1185 0.987 0.904 1.08 0.0298 0.128 0.817 0.08797 1.03 0.801 1.33 0.147 0.125 0.242 0.6167 1.16 0.906 1.48 -0.0489 0.13 0.708 0.1501 0.952 0.737 1.23 PRS_PLINK_1e.04 149.1 Cancer of oropharynx Both 152 1271 2 neoplasms darkcyan 1271, 152 318, 41 318, 34 317, 44 318, 33 -0.0927 0.0848 0.274 0.5617 0.911 0.772 1.08 -0.155 0.243 0.524 0.2807 0.857 0.533 1.38 0.0902 0.229 0.694 0.1588 1.09 0.699 1.71 -0.191 0.248 0.442 0.3551 0.826 0.508 1.34 PRS_PLINK_1e.04 149.2 Cancer of nasopharynx Both 44 442 2 neoplasms darkcyan 442, 44 111, 13 110, 10 110, 13 111, 8 -0.0332 0.153 0.828 0.0821 0.967 0.717 1.3 -0.214 0.421 0.611 0.2141 0.807 0.353 1.84 0.0206 0.401 0.959 0.01815 1.02 0.465 2.24 -0.386 0.442 0.382 0.418 0.679 0.286 1.62 PRS_PLINK_1e.04 149.3 Cancer of hypopharynx Both 32 311 2 neoplasms darkcyan 311, 32 78, 11 78, 6 77, 9 78, 6 -0.0459 0.173 0.791 0.1021 0.955 0.681 1.34 -0.414 0.512 0.419 0.378 0.661 0.243 1.8 -0.142 0.465 0.761 0.1188 0.868 0.349 2.16 -0.615 0.513 0.23 0.6374 0.541 0.198 1.48 PRS_PLINK_1e.04 149.4 Cancer of larynx Both 160 1387 2 neoplasms darkcyan 1387, 160 347, 38 347, 44 346, 47 347, 31 -0.0445 0.0813 0.584 0.2333 0.957 0.816 1.12 0.173 0.232 0.455 0.3424 1.19 0.755 1.87 0.239 0.229 0.296 0.5281 1.27 0.811 1.99 -0.177 0.251 0.482 0.3167 0.838 0.512 1.37 PRS_PLINK_1e.04 149.5 Hx of malignant neoplasm of oral cavity and pharynx Both 218 1958 2 neoplasms darkcyan 1958, 218 490, 56 489, 53 489, 56 490, 53 -0.0202 0.07 0.773 0.1116 0.98 0.854 1.12 -0.0373 0.201 0.852 0.06941 0.963 0.65 1.43 0.0276 0.197 0.889 0.05119 1.03 0.698 1.51 -0.0483 0.201 0.81 0.09169 0.953 0.643 1.41 PRS_PLINK_1e.04 149.9 Cancer of of nasal cavities Both 100 927 2 neoplasms darkcyan 927, 100 232, 21 232, 24 231, 33 232, 22 0.0147 0.107 0.891 0.05027 1.01 0.823 1.25 0.146 0.305 0.633 0.1987 1.16 0.637 2.1 0.466 0.29 0.107 0.9688 1.59 0.904 2.81 0.0646 0.313 0.837 0.07746 1.07 0.577 1.97 PRS_PLINK_1e.04 150 Cancer of esophagus Both 141 1620 2 neoplasms darkcyan 1620, 141 405, 26 405, 40 405, 35 405, 40 0.0965 0.0865 0.265 0.5774 1.1 0.93 1.3 0.427 0.256 0.0955 1.02 1.53 0.928 2.53 0.309 0.263 0.241 0.6188 1.36 0.813 2.28 0.404 0.256 0.114 0.9416 1.5 0.907 2.47 PRS_PLINK_1e.04 151 Cancer of stomach Both 154 1832 2 neoplasms darkcyan 1832, 154 458, 34 458, 47 458, 34 458, 39 0.0363 0.0834 0.664 0.1781 1.04 0.881 1.22 0.341 0.231 0.14 0.8526 1.41 0.894 2.21 0.0183 0.247 0.941 0.02641 1.02 0.628 1.65 0.134 0.239 0.575 0.2406 1.14 0.715 1.83 PRS_PLINK_1e.04 153 Colorectal cancer Both 534 5986 2 neoplasms darkcyan 5986, 534 1497, 138 1496, 143 1496, 128 1497, 125 -0.0257 0.0452 0.569 0.245 0.975 0.892 1.06 0.0414 0.124 0.739 0.1312 1.04 0.817 1.33 -0.0693 0.128 0.587 0.2316 0.933 0.727 1.2 -0.0977 0.128 0.446 0.3503 0.907 0.705 1.17 PRS_PLINK_1e.04 153.2 Colon cancer Both 410 4615 2 neoplasms darkcyan 4615, 410 1154, 106 1154, 111 1153, 96 1154, 97 -0.0297 0.0513 0.563 0.2494 0.971 0.878 1.07 0.0505 0.141 0.721 0.1422 1.05 0.797 1.39 -0.0989 0.146 0.498 0.3026 0.906 0.68 1.21 -0.0836 0.146 0.567 0.2468 0.92 0.691 1.22 PRS_PLINK_1e.04 153.3 Malignant neoplasm of rectum, rectosigmoid junction, and anus Both 325 3567 2 neoplasms darkcyan 3567, 325 892, 88 892, 88 891, 79 892, 70 -0.0775 0.0576 0.178 0.7491 0.925 0.827 1.04 -0.00592 0.157 0.97 0.01326 0.994 0.731 1.35 -0.107 0.161 0.507 0.295 0.899 0.656 1.23 -0.235 0.166 0.157 0.8039 0.791 0.571 1.09 PRS_PLINK_1e.04 155 Cancer of liver and intrahepatic bile duct Both 152 2059 2 neoplasms darkcyan 2059, 152 515, 45 515, 32 514, 35 515, 40 -0.0641 0.0824 0.437 0.36 0.938 0.798 1.1 -0.317 0.236 0.178 0.7485 0.728 0.459 1.16 -0.228 0.229 0.32 0.4951 0.796 0.508 1.25 -0.107 0.223 0.633 0.1985 0.899 0.58 1.39 PRS_PLINK_1e.04 155.1 Malignant neoplasm of liver, primary Both 98 1363 2 neoplasms darkcyan 1363, 98 341, 28 341, 25 340, 23 341, 22 -0.0703 0.101 0.488 0.3115 0.932 0.764 1.14 -0.0995 0.279 0.721 0.1419 0.905 0.524 1.56 -0.129 0.285 0.651 0.1867 0.879 0.503 1.54 -0.239 0.289 0.408 0.3894 0.787 0.447 1.39 PRS_PLINK_1e.04 157 Pancreatic cancer Both 166 1857 2 neoplasms darkcyan 1857, 166 465, 45 464, 31 464, 46 464, 44 0.00384 0.0804 0.962 0.01688 1 0.858 1.18 -0.383 0.239 0.109 0.9646 0.682 0.427 1.09 -0.00317 0.217 0.988 0.005095 0.997 0.652 1.53 -0.0167 0.22 0.939 0.02711 0.983 0.639 1.51 PRS_PLINK_1e.04 158 Neoplasm of unspecified nature of digestive system Both 532 6301 2 neoplasms darkcyan 6301, 532 1576, 128 1575, 135 1575, 142 1575, 127 -0.0519 0.0443 0.242 0.6166 0.949 0.87 1.04 0.0514 0.128 0.687 0.1631 1.05 0.82 1.35 0.0972 0.126 0.441 0.3552 1.1 0.86 1.41 -0.00513 0.129 0.968 0.01394 0.995 0.772 1.28 PRS_PLINK_1e.04 159 Malignant neoplasm of other and ill-defined sites within the digestive organs and peritoneum Both 623 7209 2 neoplasms darkcyan 7209, 623 1803, 148 1802, 173 1802, 147 1802, 155 0.00424 0.0414 0.918 0.03693 1 0.926 1.09 0.154 0.116 0.186 0.7302 1.17 0.928 1.46 -0.00276 0.121 0.982 0.007997 0.997 0.787 1.26 0.0424 0.119 0.722 0.1412 1.04 0.826 1.32 PRS_PLINK_1e.04 159.2 Malignant neoplasm of small intestine, including duodenum Both 71 893 2 neoplasms darkcyan 893, 71 224, 21 223, 17 223, 18 223, 15 -0.0991 0.131 0.45 0.347 0.906 0.7 1.17 -0.309 0.333 0.354 0.4511 0.734 0.382 1.41 -0.177 0.325 0.586 0.232 0.838 0.443 1.58 -0.356 0.339 0.294 0.5322 0.701 0.361 1.36 PRS_PLINK_1e.04 159.3 Malignant neoplasm of gallbladder and extrahepatic bile ducts Both 58 577 2 neoplasms darkcyan 577, 58 145, 21 144, 9 144, 12 144, 16 -0.0645 0.127 0.613 0.2127 0.938 0.73 1.2 -0.784 0.401 0.0507 1.295 0.456 0.208 1 -0.411 0.372 0.27 0.5689 0.663 0.319 1.38 -0.238 0.342 0.486 0.313 0.788 0.403 1.54 PRS_PLINK_1e.04 159.4 Malignant neoplasm of retroperitoneum and peritoneum Both 121 1276 2 neoplasms darkcyan 1276, 121 319, 27 319, 27 319, 39 319, 28 0.0761 0.0939 0.418 0.3789 1.08 0.898 1.3 0.00603 0.278 0.983 0.007578 1.01 0.584 1.73 0.379 0.259 0.143 0.8445 1.46 0.88 2.43 0.0491 0.275 0.858 0.06635 1.05 0.612 1.8 PRS_PLINK_1e.04 164 Cancer of intrathoracic organs Both 50 541 2 neoplasms darkcyan 541, 50 136, 13 135, 16 135, 7 135, 14 -0.204 0.131 0.12 0.919 0.816 0.631 1.05 0.166 0.384 0.666 0.1768 1.18 0.556 2.51 -0.624 0.452 0.167 0.7761 0.536 0.221 1.3 0.123 0.39 0.753 0.123 1.13 0.526 2.43 PRS_PLINK_1e.04 165 Cancer within the respiratory system Both 441 4808 2 neoplasms darkcyan 4808, 441 1202, 113 1202, 111 1202, 115 1202, 102 -0.0408 0.0491 0.406 0.3917 0.96 0.872 1.06 -0.0156 0.139 0.911 0.04053 0.985 0.75 1.29 0.0318 0.138 0.818 0.08726 1.03 0.787 1.35 -0.103 0.142 0.468 0.3301 0.902 0.683 1.19 PRS_PLINK_1e.04 165.1 Cancer of bronchus; lung Both 332 3722 2 neoplasms darkcyan 3722, 332 931, 90 930, 75 930, 87 931, 80 -0.0557 0.0568 0.327 0.4854 0.946 0.846 1.06 -0.189 0.162 0.243 0.6151 0.828 0.603 1.14 -0.0247 0.156 0.874 0.05834 0.976 0.718 1.33 -0.121 0.159 0.448 0.3488 0.886 0.648 1.21 PRS_PLINK_1e.04 170 Cancer of bone and connective tissue Both 730 7352 2 neoplasms darkcyan 7352, 730 1838, 192 1838, 172 1838, 189 1838, 177 -0.0269 0.0382 0.48 0.3186 0.973 0.903 1.05 -0.111 0.11 0.312 0.5052 0.895 0.722 1.11 -0.017 0.107 0.875 0.05822 0.983 0.796 1.21 -0.0877 0.109 0.422 0.3742 0.916 0.739 1.13 PRS_PLINK_1e.04 170.1 Bone cancer Both 306 3145 2 neoplasms darkcyan 3145, 306 787, 72 786, 72 786, 92 786, 70 0.00917 0.0592 0.877 0.05706 1.01 0.899 1.13 0.00522 0.173 0.976 0.01059 1.01 0.716 1.41 0.239 0.164 0.146 0.8369 1.27 0.92 1.75 -0.0198 0.174 0.909 0.04125 0.98 0.697 1.38 PRS_PLINK_1e.04 170.2 Cancer of connective tissue Both 533 5300 2 neoplasms darkcyan 5300, 533 1325, 143 1325, 126 1325, 130 1325, 134 -0.0358 0.0445 0.421 0.3757 0.965 0.884 1.05 -0.123 0.128 0.337 0.4718 0.885 0.689 1.14 -0.0965 0.127 0.447 0.3499 0.908 0.708 1.16 -0.0669 0.126 0.596 0.2246 0.935 0.73 1.2 PRS_PLINK_1e.04 172 Skin cancer Both 3190 16307 2 neoplasms darkcyan 16307, 3190 4076, 793 4077, 798 4076, 766 4077, 833 -0.000583 0.02 0.977 0.01024 0.999 0.961 1.04 0.00668 0.0565 0.906 0.04288 1.01 0.901 1.12 -0.0485 0.0571 0.396 0.4025 0.953 0.852 1.07 0.0411 0.0563 0.465 0.3322 1.04 0.933 1.16 PRS_PLINK_1e.04 172.1 Melanomas of skin, dx or hx Both 1971 13971 2 neoplasms darkcyan 13971, 1971 3492, 478 3493, 486 3492, 488 3493, 519 0.0196 0.0244 0.423 0.374 1.02 0.972 1.07 0.0117 0.0694 0.866 0.06244 1.01 0.883 1.16 0.0149 0.0694 0.83 0.08073 1.01 0.886 1.16 0.0735 0.0686 0.284 0.5463 1.08 0.941 1.23 PRS_PLINK_1e.04 172.11 Melanomas of skin Both 1296 11043 2 neoplasms darkcyan 11043, 1296 2760, 329 2761, 300 2760, 326 2761, 341 0.017 0.0293 0.562 0.2502 1.02 0.96 1.08 -0.0925 0.0842 0.272 0.566 0.912 0.773 1.08 -0.00959 0.0827 0.908 0.04206 0.99 0.842 1.16 0.0413 0.082 0.615 0.2113 1.04 0.887 1.22 PRS_PLINK_1e.04 172.2 Other non-epithelial cancer of skin Both 2482 14073 2 neoplasms darkcyan 14073, 2482 3518, 619 3518, 606 3518, 583 3518, 674 0.00587 0.0223 0.792 0.101 1.01 0.963 1.05 -0.0256 0.0636 0.687 0.163 0.975 0.86 1.1 -0.0864 0.0643 0.179 0.7472 0.917 0.809 1.04 0.0714 0.0624 0.253 0.5973 1.07 0.95 1.21 PRS_PLINK_1e.04 172.21 Basal cell carcinoma Both 1282 9590 2 neoplasms darkcyan 9590, 1282 2398, 318 2397, 318 2397, 306 2398, 340 0.00667 0.0299 0.823 0.08439 1.01 0.949 1.07 -0.00419 0.0849 0.961 0.01744 0.996 0.843 1.18 -0.0501 0.0857 0.559 0.2527 0.951 0.804 1.13 0.0477 0.0839 0.57 0.2442 1.05 0.89 1.24 PRS_PLINK_1e.04 172.22 Squamous cell carcinoma Both 696 6242 2 neoplasms darkcyan 6242, 696 1561, 190 1560, 177 1560, 150 1561, 179 -0.0444 0.0398 0.265 0.5771 0.957 0.885 1.03 -0.0884 0.111 0.424 0.3721 0.915 0.737 1.14 -0.246 0.115 0.0327 1.485 0.782 0.624 0.98 -0.0686 0.11 0.534 0.2723 0.934 0.752 1.16 PRS_PLINK_1e.04 172.3 Carcinoma in situ of skin Both 444 4257 2 neoplasms darkcyan 4257, 444 1065, 126 1064, 126 1064, 91 1064, 101 -0.0792 0.0488 0.105 0.9798 0.924 0.84 1.02 0.00499 0.133 0.97 0.01318 1.01 0.774 1.3 -0.335 0.143 0.0196 1.707 0.715 0.54 0.948 -0.235 0.14 0.0936 1.029 0.791 0.601 1.04 PRS_PLINK_1e.04 173 Neoplasm of uncertain behavior of skin Both 775 8071 2 neoplasms darkcyan 8071, 775 2018, 193 2018, 194 2017, 188 2018, 200 0.0223 0.0374 0.551 0.2586 1.02 0.95 1.1 0.00105 0.106 0.992 0.003458 1 0.813 1.23 -0.0286 0.107 0.789 0.1031 0.972 0.788 1.2 0.0389 0.105 0.712 0.1475 1.04 0.846 1.28 PRS_PLINK_1e.04 174 Breast cancer Both 1597 8141 2 neoplasms darkcyan 8141, 1597 2036, 356 2035, 405 2035, 407 2035, 429 0.0511 0.0282 0.07 1.155 1.05 0.996 1.11 0.132 0.0803 0.0998 1.001 1.14 0.975 1.34 0.133 0.08 0.0962 1.017 1.14 0.977 1.34 0.194 0.0793 0.0143 1.843 1.21 1.04 1.42 PRS_PLINK_1e.04 174.1 Breast cancer [female] Female 1542 7813 2 neoplasms darkcyan 7813, 1542 1954, 339 1953, 394 1953, 390 1953, 419 0.0612 0.0287 0.033 1.481 1.06 1 1.12 0.154 0.082 0.0597 1.224 1.17 0.994 1.37 0.14 0.0819 0.0867 1.062 1.15 0.98 1.35 0.223 0.0808 0.00587 2.231 1.25 1.07 1.46 PRS_PLINK_1e.04 174.11 Malignant neoplasm of female breast Female 1520 7764 2 neoplasms darkcyan 7764, 1520 1941, 333 1941, 386 1941, 386 1941, 415 0.0663 0.0289 0.0219 1.66 1.07 1.01 1.13 0.148 0.0827 0.074 1.131 1.16 0.986 1.36 0.145 0.0824 0.0786 1.104 1.16 0.984 1.36 0.227 0.0813 0.00522 2.282 1.25 1.07 1.47 PRS_PLINK_1e.04 174.3 Neoplasm of uncertain behavior of breast Both 107 1115 2 neoplasms darkcyan 1115, 107 279, 22 279, 26 278, 31 279, 28 0.0758 0.103 0.462 0.3355 1.08 0.881 1.32 0.152 0.296 0.607 0.217 1.16 0.652 2.08 PRS_PLINK_1e.04 175 Acquired absence of breast Female 504 4737 2 neoplasms darkcyan 4737, 504 1185, 123 1184, 132 1184, 130 1184, 119 0.00092 0.0478 0.985 0.006724 1 0.911 1.1 0.0786 0.132 0.552 0.2583 1.08 0.835 1.4 0.0627 0.132 0.635 0.1974 1.06 0.822 1.38 -0.0247 0.135 0.855 0.06822 0.976 0.749 1.27 PRS_PLINK_1e.04 180 Cervical cancer and dysplasia Female 892 7316 2 neoplasms darkcyan 7316, 892 1829, 220 1829, 236 1829, 197 1829, 238 0.00675 0.0355 0.849 0.07111 1.01 0.939 1.08 0.064 0.0995 0.52 0.2839 1.07 0.877 1.3 -0.118 0.103 0.254 0.5946 0.889 0.726 1.09 0.0724 0.0991 0.465 0.3323 1.08 0.885 1.31 PRS_PLINK_1e.04 180.1 Cervical cancer Female 274 2762 2 neoplasms darkcyan 2762, 274 691, 66 690, 77 690, 62 691, 69 0.0123 0.0635 0.846 0.07243 1.01 0.894 1.15 0.16 0.175 0.362 0.4413 1.17 0.832 1.65 -0.0788 0.183 0.668 0.1755 0.924 0.645 1.32 0.0365 0.179 0.838 0.07658 1.04 0.731 1.47 PRS_PLINK_1e.04 180.3 Cervical intraepithelial neoplasia [CIN] [Cervical dysplasia] Female 696 6099 2 neoplasms darkcyan 6099, 696 1525, 173 1525, 183 1524, 150 1525, 189 0.00356 0.0397 0.928 0.03223 1 0.928 1.08 0.0535 0.112 0.633 0.1983 1.05 0.847 1.31 -0.144 0.117 0.22 0.658 0.866 0.688 1.09 0.0823 0.111 0.459 0.3381 1.09 0.873 1.35 PRS_PLINK_1e.04 182 Malignant neoplasm of uterus Female 271 3281 2 neoplasms darkcyan 3281, 271 821, 66 820, 70 820, 73 820, 62 -0.0112 0.0635 0.86 0.06574 0.989 0.873 1.12 0.0538 0.177 0.762 0.1182 1.06 0.745 1.49 0.105 0.176 0.548 0.2608 1.11 0.787 1.57 -0.0643 0.182 0.724 0.1403 0.938 0.656 1.34 PRS_PLINK_1e.04 184 Cancer of other female genital organs Female 528 5611 2 neoplasms darkcyan 5611, 528 1403, 132 1403, 148 1402, 118 1403, 130 -0.0245 0.0461 0.594 0.226 0.976 0.892 1.07 0.123 0.125 0.325 0.4884 1.13 0.885 1.45 -0.105 0.132 0.427 0.3699 0.901 0.696 1.17 -0.00666 0.129 0.959 0.01831 0.993 0.772 1.28 PRS_PLINK_1e.04 184.1 Malignant neoplasm of ovary and other uterine adnexa Female 251 2639 2 neoplasms darkcyan 2639, 251 660, 49 660, 73 659, 59 660, 70 0.0904 0.0676 0.182 0.7408 1.09 0.959 1.25 0.395 0.192 0.0393 1.405 1.48 1.02 2.16 0.204 0.199 0.306 0.5137 1.23 0.83 1.81 0.388 0.193 0.0442 1.354 1.47 1.01 2.15 PRS_PLINK_1e.04 184.11 Malignant neoplasm of ovary Female 198 2037 2 neoplasms darkcyan 2037, 198 510, 40 509, 57 509, 48 509, 53 0.0682 0.0768 0.374 0.4271 1.07 0.921 1.24 0.354 0.213 0.0962 1.017 1.42 0.939 2.16 0.202 0.22 0.358 0.446 1.22 0.796 1.88 0.284 0.216 0.188 0.7249 1.33 0.87 2.03 PRS_PLINK_1e.04 184.2 Cancer of other female genital organs (excluding uterus and ovary) Female 257 2877 2 neoplasms darkcyan 2877, 257 720, 73 719, 66 719, 53 719, 65 -0.0603 0.0658 0.359 0.4445 0.941 0.828 1.07 -0.0764 0.177 0.665 0.1769 0.926 0.655 1.31 -0.305 0.186 0.101 0.997 0.737 0.512 1.06 -0.123 0.177 0.486 0.3136 0.884 0.625 1.25 PRS_PLINK_1e.04 185 Cancer of prostate Male 904 3884 2 neoplasms darkcyan 3884, 904 971, 218 971, 239 971, 226 971, 221 0.000692 0.0382 0.986 0.006324 1 0.928 1.08 0.102 0.11 0.353 0.4522 1.11 0.893 1.37 0.0129 0.111 0.908 0.04211 1.01 0.815 1.26 -0.0279 0.111 0.802 0.09602 0.972 0.782 1.21 PRS_PLINK_1e.04 187 Cancer of other male genital organs Male 150 1440 2 neoplasms darkcyan 1440, 150 360, 33 360, 46 360, 34 360, 37 -0.00881 0.0828 0.915 0.03844 0.991 0.843 1.17 0.346 0.237 0.145 0.8401 1.41 0.888 2.25 0.012 0.252 0.962 0.0168 1.01 0.618 1.66 0.0903 0.246 0.714 0.1464 1.09 0.675 1.77 PRS_PLINK_1e.04 187.1 Malignant neoplasm of unspecified male genital organ Male 39 382 2 neoplasms darkcyan 382, 39 96, 11 95, 10 95, 9 96, 9 -0.129 0.143 0.364 0.4384 0.879 0.664 1.16 -0.0362 0.442 0.935 0.02935 0.964 0.406 2.29 -0.181 0.445 0.684 0.1647 0.834 0.349 2 -0.184 0.448 0.68 0.1672 0.832 0.346 2 PRS_PLINK_1e.04 187.2 Malignant neoplasm of testis Male 100 935 2 neoplasms darkcyan 935, 100 234, 19 234, 34 233, 24 234, 23 0.0426 0.103 0.68 0.1673 1.04 0.852 1.28 0.574 0.296 0.0524 1.281 1.78 0.994 3.17 0.209 0.311 0.502 0.2993 1.23 0.669 2.27 0.135 0.316 0.668 0.175 1.14 0.616 2.13 PRS_PLINK_1e.04 187.8 Neoplasm of uncertain behavior of male genital organs Male 21 177 2 neoplasms darkcyan 177, 21 45, 8 44, 5 44, 2 44, 6 -0.39 0.218 0.0739 1.131 0.677 0.442 1.04 -0.507 0.591 0.392 0.4071 0.603 0.189 1.92 -1.15 0.716 0.109 0.9631 0.317 0.0779 1.29 -0.222 0.568 0.695 0.1578 0.801 0.263 2.44 PRS_PLINK_1e.04 189 Cancer of urinary organs (incl. kidney and bladder) Both 844 9163 2 neoplasms darkcyan 9163, 844 2291, 208 2291, 214 2290, 208 2291, 214 0.00494 0.0359 0.89 0.05044 1 0.937 1.08 0.0358 0.102 0.726 0.1392 1.04 0.849 1.27 0.025 0.103 0.807 0.09315 1.03 0.839 1.25 0.0515 0.102 0.614 0.212 1.05 0.862 1.29 PRS_PLINK_1e.04 189.1 Cancer of kidney and renal pelvis Both 368 5494 2 neoplasms darkcyan 5494, 368 1374, 85 1373, 87 1373, 99 1374, 97 0.0365 0.0535 0.495 0.3052 1.04 0.934 1.15 0.019 0.156 0.903 0.04424 1.02 0.751 1.38 0.163 0.152 0.283 0.5478 1.18 0.874 1.59 0.169 0.153 0.27 0.5688 1.18 0.877 1.6 PRS_PLINK_1e.04 189.11 Malignant neoplasm of kidney, except pelvis Both 312 4813 2 neoplasms darkcyan 4813, 312 1204, 78 1203, 64 1203, 83 1203, 87 0.0357 0.0578 0.537 0.2697 1.04 0.925 1.16 -0.205 0.172 0.234 0.6308 0.815 0.582 1.14 0.079 0.162 0.626 0.2034 1.08 0.788 1.49 0.155 0.161 0.335 0.4753 1.17 0.852 1.6 PRS_PLINK_1e.04 189.12 Malignant neoplasm of renal pelvis Both 54 751 2 neoplasms darkcyan 751, 54 188, 14 188, 12 187, 19 188, 9 -0.0776 0.139 0.577 0.2389 0.925 0.705 1.22 -0.235 0.391 0.548 0.261 0.791 0.367 1.7 0.251 0.364 0.49 0.3098 1.29 0.63 2.62 -0.448 0.419 0.285 0.545 0.639 0.281 1.45 PRS_PLINK_1e.04 189.2 Cancer of bladder Both 541 5243 2 neoplasms darkcyan 5243, 541 1311, 137 1311, 136 1310, 139 1311, 129 -0.0257 0.0447 0.565 0.2479 0.975 0.893 1.06 -0.0175 0.127 0.89 0.05051 0.983 0.766 1.26 0.0235 0.126 0.852 0.06953 1.02 0.799 1.31 -0.0528 0.129 0.682 0.1665 0.949 0.737 1.22 PRS_PLINK_1e.04 189.21 Malignant neoplasm of bladder Both 495 4761 2 neoplasms darkcyan 4761, 495 1191, 131 1190, 118 1190, 124 1190, 122 -0.0365 0.0466 0.433 0.3631 0.964 0.88 1.06 -0.112 0.133 0.401 0.3974 0.894 0.689 1.16 -0.0425 0.132 0.747 0.1268 0.958 0.741 1.24 -0.0553 0.132 0.675 0.1705 0.946 0.73 1.23 PRS_PLINK_1e.04 189.4 Malignant neoplasm of other urinary organs Both 181 2012 2 neoplasms darkcyan 2012, 181 503, 45 503, 55 503, 42 503, 39 -0.028 0.0774 0.717 0.1443 0.972 0.835 1.13 0.192 0.208 0.356 0.4491 1.21 0.806 1.82 -0.0641 0.221 0.772 0.1125 0.938 0.608 1.45 -0.124 0.224 0.582 0.2354 0.884 0.569 1.37 PRS_PLINK_1e.04 190 Cancer of eye Both 49 500 2 neoplasms darkcyan 500, 49 125, 22 125, 9 125, 8 125, 10 -0.382 0.143 0.00755 2.122 0.682 0.516 0.903 -0.823 0.398 0.0385 1.414 0.439 0.201 0.957 -0.965 0.41 0.0186 1.73 0.381 0.17 0.851 -0.684 0.384 0.0752 1.124 0.505 0.238 1.07 PRS_PLINK_1e.04 191 Manlignant and unknown neoplasms of brain and nervous system Both 511 5369 2 neoplasms darkcyan 5369, 511 1343, 129 1342, 129 1342, 137 1342, 116 -0.0189 0.0456 0.679 0.1682 0.981 0.897 1.07 0.000944 0.13 0.994 0.00253 1 0.776 1.29 0.0573 0.128 0.655 0.184 1.06 0.824 1.36 -0.104 0.133 0.436 0.3605 0.902 0.695 1.17 PRS_PLINK_1e.04 191.1 Cancer of brain and nervous system Both 337 3509 2 neoplasms darkcyan 3509, 337 878, 85 877, 84 877, 85 877, 83 0.00197 0.0555 0.972 0.01244 1 0.899 1.12 -0.0166 0.16 0.917 0.03747 0.984 0.719 1.35 -0.00601 0.16 0.97 0.01325 0.994 0.727 1.36 -0.0231 0.16 0.886 0.05275 0.977 0.714 1.34 PRS_PLINK_1e.04 191.11 Cancer of brain Both 297 3068 2 neoplasms darkcyan 3068, 297 767, 70 767, 73 767, 77 767, 77 0.0408 0.0604 0.5 0.3013 1.04 0.925 1.17 0.0422 0.173 0.808 0.09279 1.04 0.743 1.47 0.0764 0.172 0.656 0.1831 1.08 0.771 1.51 0.0977 0.171 0.568 0.2455 1.1 0.788 1.54 PRS_PLINK_1e.04 193 Thyroid cancer Both 451 4935 2 neoplasms darkcyan 4935, 451 1234, 125 1234, 128 1233, 110 1234, 88 -0.134 0.0476 0.00492 2.308 0.875 0.797 0.96 0.0326 0.132 0.804 0.0945 1.03 0.798 1.34 -0.129 0.136 0.342 0.4665 0.879 0.673 1.15 -0.341 0.144 0.018 1.744 0.711 0.536 0.943 PRS_PLINK_1e.04 194 Cancer of other endocrine glands Both 235 2816 2 neoplasms darkcyan 2816, 235 704, 62 704, 67 704, 59 704, 47 -0.107 0.0656 0.102 0.9911 0.898 0.79 1.02 0.0592 0.182 0.746 0.1275 1.06 0.742 1.52 -0.0143 0.189 0.94 0.02707 0.986 0.681 1.43 -0.239 0.199 0.23 0.6381 0.787 0.532 1.16 PRS_PLINK_1e.04 195 Cancer, suspected or other Both 6612 14992 2 neoplasms darkcyan 14992, 6612 3747, 1674 3748, 1681 3748, 1614 3748, 1643 -0.0257 0.0159 0.106 0.9761 0.975 0.945 1.01 0.0142 0.0447 0.751 0.1243 1.01 0.929 1.11 -0.0437 0.0449 0.331 0.4804 0.957 0.877 1.05 -0.0278 0.0449 0.537 0.2704 0.973 0.891 1.06 PRS_PLINK_1e.04 195.1 Malignant neoplasm, other Both 6493 14983 2 neoplasms darkcyan 14983, 6493 3745, 1630 3746, 1652 3745, 1587 3746, 1624 -0.0217 0.016 0.175 0.7581 0.979 0.948 1.01 0.0216 0.045 0.632 0.1991 1.02 0.935 1.12 -0.0334 0.0453 0.46 0.3372 0.967 0.885 1.06 -0.0133 0.0452 0.768 0.1145 0.987 0.903 1.08 PRS_PLINK_1e.04 195.3 Malignant neoplasm of head, face, and neck Both 440 3879 2 neoplasms darkcyan 3879, 440 970, 104 970, 112 969, 125 970, 99 -0.0202 0.0506 0.69 0.1612 0.98 0.888 1.08 0.0611 0.143 0.67 0.1741 1.06 0.803 1.41 0.197 0.14 0.159 0.7986 1.22 0.926 1.6 -0.0506 0.147 0.731 0.1361 0.951 0.712 1.27 PRS_PLINK_1e.04 196 Radiotherapy Both 964 7772 2 neoplasms darkcyan 7772, 964 1943, 215 1943, 245 1943, 272 1943, 232 0.0179 0.0343 0.601 0.2209 1.02 0.952 1.09 0.121 0.0992 0.223 0.6526 1.13 0.929 1.37 0.217 0.0971 0.0256 1.592 1.24 1.03 1.5 0.0675 0.1 0.5 0.3008 1.07 0.879 1.3 PRS_PLINK_1e.04 197 Chemotherapy Both 1998 12925 2 neoplasms darkcyan 12925, 1998 3231, 474 3231, 501 3231, 513 3231, 510 0.00329 0.0246 0.893 0.04894 1 0.956 1.05 0.066 0.0703 0.348 0.4587 1.07 0.931 1.23 0.0704 0.0697 0.313 0.5048 1.07 0.936 1.23 0.077 0.0699 0.27 0.5685 1.08 0.942 1.24 PRS_PLINK_1e.04 198 Secondary malignant neoplasm Both 2300 12782 2 neoplasms darkcyan 12782, 2300 3195, 576 3195, 583 3195, 560 3196, 581 -0.0206 0.0231 0.371 0.4304 0.98 0.936 1.02 0.0225 0.0655 0.732 0.1357 1.02 0.899 1.16 -0.0292 0.0661 0.659 0.1814 0.971 0.853 1.11 0.00667 0.0658 0.919 0.03658 1.01 0.885 1.15 PRS_PLINK_1e.04 198.1 Secondary malignancy of lymph nodes Both 1585 11268 2 neoplasms darkcyan 11268, 1585 2816, 388 2817, 389 2817, 410 2817, 398 -0.00896 0.0269 0.739 0.1312 0.991 0.94 1.04 0.0115 0.0771 0.881 0.05489 1.01 0.87 1.18 0.0491 0.0764 0.52 0.2837 1.05 0.904 1.22 0.0248 0.0771 0.748 0.1261 1.03 0.881 1.19 PRS_PLINK_1e.04 198.2 Secondary malignancy of respiratory organs Both 378 4481 2 neoplasms darkcyan 4481, 378 1121, 99 1120, 93 1120, 92 1120, 94 -0.0229 0.0528 0.665 0.1773 0.977 0.881 1.08 -0.0728 0.15 0.627 0.2029 0.93 0.693 1.25 -0.0743 0.15 0.62 0.2074 0.928 0.692 1.25 -0.0474 0.149 0.751 0.1246 0.954 0.712 1.28 PRS_PLINK_1e.04 198.3 Secondary malignant neoplasm of digestive systems Both 323 3640 2 neoplasms darkcyan 3640, 323 910, 81 910, 85 910, 84 910, 73 -0.0755 0.0576 0.19 0.7221 0.927 0.828 1.04 0.0393 0.161 0.807 0.09299 1.04 0.758 1.43 0.0427 0.162 0.792 0.1013 1.04 0.76 1.43 -0.105 0.167 0.528 0.2772 0.9 0.649 1.25 PRS_PLINK_1e.04 198.4 Secondary malignant neoplasm of liver Both 279 3281 2 neoplasms darkcyan 3281, 279 821, 70 820, 69 820, 67 820, 73 -0.0484 0.0601 0.421 0.3756 0.953 0.847 1.07 -0.0333 0.176 0.849 0.07086 0.967 0.686 1.36 -0.0323 0.176 0.855 0.06821 0.968 0.685 1.37 0.0226 0.173 0.896 0.04766 1.02 0.728 1.44 PRS_PLINK_1e.04 198.5 Secondary malignancy of brain/spine Both 262 2753 2 neoplasms darkcyan 2753, 262 689, 65 688, 66 688, 67 688, 64 0.0272 0.0641 0.671 0.1734 1.03 0.906 1.17 -0.00522 0.182 0.977 0.01007 0.995 0.697 1.42 0.0247 0.181 0.891 0.04998 1.03 0.719 1.46 -0.0177 0.183 0.923 0.03496 0.982 0.687 1.41 PRS_PLINK_1e.04 198.6 Secondary malignancy of bone Both 313 3410 2 neoplasms darkcyan 3410, 313 853, 83 852, 80 852, 85 853, 65 -0.0759 0.0574 0.186 0.7293 0.927 0.828 1.04 -0.0461 0.163 0.778 0.1092 0.955 0.694 1.31 0.0308 0.161 0.848 0.07178 1.03 0.753 1.41 -0.244 0.172 0.156 0.8057 0.784 0.56 1.1 PRS_PLINK_1e.04 198.7 Secondary malignant neoplasm of skin Both 115 1253 2 neoplasms darkcyan 1253, 115 314, 27 313, 26 313, 25 313, 37 0.122 0.0959 0.204 0.691 1.13 0.936 1.36 -0.022 0.28 0.937 0.02813 0.978 0.565 1.69 -0.0616 0.283 0.828 0.08221 0.94 0.54 1.64 0.324 0.261 0.214 0.6692 1.38 0.829 2.3 PRS_PLINK_1e.04 199 Neoplasm of uncertain behavior Both 2200 14451 2 neoplasms darkcyan 14451, 2200 3612, 540 3613, 561 3612, 557 3613, 542 -0.0206 0.0232 0.375 0.4264 0.98 0.936 1.03 0.0491 0.0658 0.455 0.3418 1.05 0.923 1.19 0.0367 0.0657 0.577 0.2387 1.04 0.912 1.18 0.00285 0.0662 0.966 0.01515 1 0.881 1.14 PRS_PLINK_1e.04 199.4 Neurofibromatosis Both 52 551 2 neoplasms darkcyan 551, 52 138, 12 138, 18 137, 13 138, 9 -0.0864 0.137 0.53 0.276 0.917 0.701 1.2 0.389 0.381 0.308 0.512 1.47 0.699 3.11 0.0853 0.401 0.832 0.08013 1.09 0.496 2.39 -0.316 0.428 0.46 0.3374 0.729 0.315 1.69 PRS_PLINK_1e.04 200 Myeloproliferative disease Both 335 4765 2 neoplasms darkcyan 4765, 335 1192, 84 1191, 72 1191, 105 1191, 74 -0.0469 0.0568 0.409 0.3885 0.954 0.854 1.07 -0.157 0.164 0.337 0.4718 0.855 0.62 1.18 0.21 0.151 0.163 0.7876 1.23 0.918 1.66 -0.127 0.163 0.436 0.3603 0.881 0.64 1.21 PRS_PLINK_1e.04 200.1 Polycythemia vera Both 45 897 2 neoplasms darkcyan 897, 45 225, 11 224, 15 224, 11 224, 8 -0.215 0.151 0.154 0.8131 0.807 0.601 1.08 0.289 0.382 0.45 0.3468 1.33 0.631 2.82 -0.124 0.412 0.764 0.1171 0.884 0.394 1.98 -0.337 0.43 0.433 0.3634 0.714 0.307 1.66 PRS_PLINK_1e.04 201 Hodgkin's disease Both 78 837 2 neoplasms darkcyan 837, 78 210, 13 209, 19 209, 23 209, 23 0.245 0.118 0.0376 1.425 1.28 1.01 1.61 0.4 0.36 0.266 0.5744 1.49 0.737 3.02 0.537 0.345 0.12 0.921 1.71 0.87 3.36 0.571 0.349 0.101 0.994 1.77 0.894 3.5 PRS_PLINK_1e.04 202 Cancer of other lymphoid, histiocytic tissue Both 597 6415 2 neoplasms darkcyan 6415, 597 1604, 142 1604, 141 1603, 162 1604, 152 -0.00255 0.0425 0.952 0.02131 0.997 0.918 1.08 0.000145 0.124 0.999 0.0004082 1 0.785 1.27 0.141 0.12 0.237 0.6245 1.15 0.911 1.46 0.0835 0.121 0.492 0.3082 1.09 0.857 1.38 PRS_PLINK_1e.04 202.2 Non-Hodgkins lymphoma Both 516 5427 2 neoplasms darkcyan 5427, 516 1357, 129 1357, 115 1356, 144 1357, 128 -0.0219 0.0454 0.629 0.2012 0.978 0.895 1.07 -0.108 0.133 0.416 0.3806 0.897 0.691 1.17 0.12 0.127 0.344 0.4631 1.13 0.879 1.44 0.0125 0.13 0.924 0.03449 1.01 0.785 1.31 PRS_PLINK_1e.04 202.21 Nodular lymphoma Both 279 2879 2 neoplasms darkcyan 2879, 279 720, 70 720, 63 719, 78 720, 68 -0.0353 0.0608 0.562 0.2505 0.965 0.857 1.09 -0.0862 0.18 0.631 0.1997 0.917 0.645 1.3 0.0804 0.171 0.639 0.1945 1.08 0.775 1.52 -0.0058 0.177 0.974 0.01152 0.994 0.703 1.41 PRS_PLINK_1e.04 202.22 Reticulosarcoma Both 58 653 2 neoplasms darkcyan 653, 58 164, 17 163, 14 163, 13 163, 14 -0.0563 0.131 0.666 0.1763 0.945 0.732 1.22 -0.0994 0.37 0.788 0.1033 0.905 0.438 1.87 -0.235 0.369 0.524 0.2804 0.791 0.383 1.63 -0.146 0.365 0.689 0.1616 0.864 0.422 1.77 PRS_PLINK_1e.04 202.24 Large cell lymphoma Both 50 586 2 neoplasms darkcyan 586, 50 147, 14 146, 7 146, 16 147, 13 0.0117 0.144 0.935 0.02913 1.01 0.763 1.34 -0.578 0.438 0.187 0.7279 0.561 0.238 1.32 0.16 0.373 0.668 0.1754 1.17 0.565 2.44 -0.086 0.387 0.824 0.08394 0.918 0.43 1.96 PRS_PLINK_1e.04 204 Leukemia Both 202 2550 2 neoplasms darkcyan 2550, 202 638, 46 637, 60 637, 46 638, 50 -0.0132 0.0712 0.853 0.06885 0.987 0.858 1.13 0.276 0.201 0.17 0.7693 1.32 0.888 1.95 0.00836 0.213 0.969 0.01383 1.01 0.664 1.53 0.0864 0.208 0.678 0.1689 1.09 0.725 1.64 PRS_PLINK_1e.04 204.1 Lymphoid leukemia Both 80 901 2 neoplasms darkcyan 901, 80 226, 21 225, 26 225, 16 225, 17 -0.126 0.114 0.27 0.5694 0.882 0.705 1.1 0.165 0.301 0.584 0.2336 1.18 0.653 2.13 -0.232 0.334 0.486 0.3133 0.793 0.412 1.52 -0.224 0.328 0.495 0.3056 0.799 0.42 1.52 PRS_PLINK_1e.04 204.11 Lymphoid leukemia, acute Both 25 384 2 neoplasms darkcyan 384, 25 96, 8 96, 5 96, 9 96, 3 -0.16 0.183 0.383 0.4173 0.852 0.595 1.22 -0.389 0.531 0.464 0.3331 0.678 0.239 1.92 0.149 0.477 0.756 0.1217 1.16 0.455 2.96 -0.844 0.624 0.176 0.7545 0.43 0.127 1.46 PRS_PLINK_1e.04 204.12 Lymphoid leukemia, chronic Both 60 561 2 neoplasms darkcyan 561, 60 141, 14 140, 21 140, 9 140, 16 -0.0851 0.131 0.517 0.2861 0.918 0.71 1.19 0.437 0.36 0.225 0.6487 1.55 0.765 3.13 -0.437 0.428 0.307 0.5134 0.646 0.279 1.49 0.175 0.381 0.646 0.1895 1.19 0.565 2.51 PRS_PLINK_1e.04 204.2 Myeloid leukemia Both 69 1020 2 neoplasms darkcyan 1020, 69 255, 11 255, 29 255, 16 255, 13 -0.021 0.12 0.861 0.06517 0.979 0.774 1.24 0.924 0.35 0.00824 2.084 2.52 1.27 5 0.352 0.378 0.351 0.4541 1.42 0.678 2.98 0.17 0.389 0.663 0.1788 1.19 0.553 2.54 PRS_PLINK_1e.04 204.21 Myeloid leukemia, acute Both 37 580 2 neoplasms darkcyan 580, 37 145, 6 145, 13 145, 9 145, 9 0.0441 0.158 0.781 0.1074 1.05 0.766 1.43 0.639 0.48 0.183 0.7382 1.9 0.74 4.85 0.259 0.494 0.6 0.2217 1.3 0.492 3.41 0.496 0.489 0.311 0.5077 1.64 0.63 4.28 PRS_PLINK_1e.04 204.22 Myeloid leukemia, chronic Both 16 245 2 neoplasms darkcyan 245, 16 62, 2 61, 5 61, 4 61, 5 0.292 0.261 0.262 0.5816 1.34 0.804 2.23 0.976 0.755 0.196 0.7078 2.65 0.605 11.6 0.448 0.734 0.541 0.2665 1.57 0.371 6.6 0.707 0.72 0.326 0.4862 2.03 0.494 8.31 PRS_PLINK_1e.04 204.4 Multiple myeloma Both 50 724 2 neoplasms darkcyan 724, 50 181, 13 181, 8 181, 18 181, 11 0.0863 0.145 0.551 0.259 1.09 0.821 1.45 -0.428 0.428 0.318 0.4975 0.652 0.282 1.51 0.295 0.362 0.415 0.3819 1.34 0.661 2.73 -0.146 0.397 0.713 0.1471 0.864 0.397 1.88 PRS_PLINK_1e.04 208 Benign neoplasm of colon Both 3716 18648 2 neoplasms darkcyan 18648, 3716 4661, 956 4662, 923 4662, 941 4662, 896 -0.0188 0.0183 0.304 0.517 0.981 0.947 1.02 -0.0317 0.0517 0.54 0.2676 0.969 0.876 1.07 -0.0194 0.0514 0.707 0.1508 0.981 0.887 1.08 -0.0723 0.052 0.164 0.784 0.93 0.84 1.03 PRS_PLINK_1e.04 209 Neuroendocrine tumors Both 85 1024 2 neoplasms darkcyan 1024, 85 256, 20 256, 30 256, 20 256, 15 -0.17 0.111 0.125 0.9045 0.843 0.678 1.05 0.367 0.293 0.21 0.6782 1.44 0.813 2.56 0.0158 0.322 0.961 0.01732 1.02 0.541 1.91 -0.31 0.337 0.359 0.4453 0.734 0.379 1.42 PRS_PLINK_1e.04 210 Benign neoplasm of lip, oral cavity, and pharynx Both 929 8904 2 neoplasms darkcyan 8904, 929 2226, 251 2226, 207 2226, 237 2226, 234 -0.00297 0.0343 0.931 0.03108 0.997 0.932 1.07 -0.193 0.0983 0.0494 1.306 0.824 0.68 1 -0.0535 0.0952 0.574 0.241 0.948 0.787 1.14 -0.0724 0.0954 0.448 0.3487 0.93 0.771 1.12 PRS_PLINK_1e.04 211 Benign neoplasm of other parts of digestive system Both 2855 19297 2 neoplasms darkcyan 19297, 2855 4824, 686 4824, 717 4824, 743 4824, 709 0.00493 0.0202 0.807 0.09317 1 0.966 1.05 0.0435 0.0573 0.447 0.3493 1.04 0.934 1.17 0.0717 0.0569 0.207 0.6832 1.07 0.961 1.2 0.0264 0.0574 0.646 0.1897 1.03 0.917 1.15 PRS_PLINK_1e.04 212 Benign neoplasm of respiratory and intrathoracic organs Both 784 8392 2 neoplasms darkcyan 8392, 784 2098, 178 2098, 223 2098, 209 2098, 174 -0.0177 0.0368 0.63 0.2009 0.982 0.914 1.06 0.231 0.105 0.0278 1.556 1.26 1.03 1.55 0.165 0.106 0.119 0.9243 1.18 0.958 1.45 -0.0171 0.111 0.877 0.05689 0.983 0.792 1.22 PRS_PLINK_1e.04 213 Benign neoplasm of bone and articular cartilage Both 781 8398 2 neoplasms darkcyan 8398, 781 2100, 206 2099, 209 2099, 171 2100, 195 -0.0644 0.0375 0.0854 1.069 0.938 0.871 1.01 0.0118 0.103 0.909 0.0416 1.01 0.828 1.24 -0.184 0.107 0.0865 1.063 0.832 0.674 1.03 -0.0611 0.104 0.558 0.2531 0.941 0.767 1.15 PRS_PLINK_1e.04 214 Lipoma Both 620 6623 2 neoplasms darkcyan 6623, 620 1655, 149 1656, 150 1655, 164 1656, 157 0.0387 0.042 0.357 0.4469 1.04 0.957 1.13 0.00538 0.12 0.964 0.01578 1.01 0.794 1.27 0.0973 0.118 0.409 0.3878 1.1 0.875 1.39 0.0576 0.119 0.629 0.2015 1.06 0.839 1.34 PRS_PLINK_1e.04 214.1 Lipoma of skin and subcutaneous tissue Both 398 4185 2 neoplasms darkcyan 4185, 398 1047, 86 1046, 103 1046, 102 1046, 107 0.0803 0.0532 0.131 0.8822 1.08 0.976 1.2 0.186 0.151 0.219 0.6598 1.2 0.895 1.62 0.174 0.152 0.252 0.5994 1.19 0.884 1.6 0.22 0.15 0.143 0.8435 1.25 0.928 1.67 PRS_PLINK_1e.04 215 Other benign neoplasm of connective and other soft tissue Both 2032 19582 2 neoplasms darkcyan 19582, 2032 4895, 530 4895, 511 4895, 491 4896, 500 -0.0253 0.0233 0.279 0.5548 0.975 0.931 1.02 -0.0369 0.0652 0.571 0.2431 0.964 0.848 1.1 -0.0751 0.0658 0.254 0.5957 0.928 0.815 1.06 -0.06 0.0655 0.36 0.444 0.942 0.828 1.07 PRS_PLINK_1e.04 216 Benign neoplasm of skin Both 5227 18052 2 neoplasms darkcyan 18052, 5227 4513, 1292 4513, 1268 4513, 1307 4513, 1359 0.0162 0.0159 0.308 0.5117 1.02 0.985 1.05 -0.0216 0.0453 0.634 0.198 0.979 0.895 1.07 0.00359 0.0451 0.937 0.02845 1 0.919 1.1 0.0435 0.0447 0.331 0.4803 1.04 0.957 1.14 PRS_PLINK_1e.04 216.1 Screening for malignant neoplasms of the skin Both 88 848 2 neoplasms darkcyan 848, 88 212, 17 212, 34 212, 16 212, 21 0.0625 0.112 0.576 0.2396 1.06 0.855 1.33 0.693 0.306 0.0236 1.627 2 1.1 3.64 -0.0733 0.348 0.833 0.07927 0.929 0.47 1.84 0.311 0.332 0.35 0.456 1.36 0.711 2.62 PRS_PLINK_1e.04 217 Vascular hamartomas and non-neoplastic nevi Both 797 7209 2 neoplasms darkcyan 7209, 797 1803, 196 1802, 207 1802, 199 1802, 195 -0.0181 0.037 0.624 0.2046 0.982 0.913 1.06 0.0538 0.105 0.608 0.2165 1.06 0.859 1.3 0.0131 0.106 0.901 0.04529 1.01 0.824 1.25 -0.00533 0.106 0.96 0.01775 0.995 0.808 1.22 PRS_PLINK_1e.04 217.1 Nevus, non-neoplastic Both 725 6575 2 neoplasms darkcyan 6575, 725 1644, 178 1644, 185 1643, 183 1644, 179 -0.0118 0.0389 0.762 0.1183 0.988 0.916 1.07 0.0364 0.11 0.742 0.1298 1.04 0.835 1.29 0.0257 0.11 0.816 0.08836 1.03 0.826 1.27 0.00463 0.111 0.967 0.01468 1 0.808 1.25 PRS_PLINK_1e.04 218 Benign neoplasm of uterus Female 2393 9453 2 neoplasms darkcyan 9453, 2393 2364, 599 2363, 577 2363, 610 2363, 606 0.0118 0.0231 0.611 0.2142 1.01 0.967 1.06 -0.0375 0.0653 0.566 0.2469 0.963 0.847 1.09 0.0193 0.0647 0.765 0.1164 1.02 0.898 1.16 0.0116 0.0648 0.858 0.06666 1.01 0.891 1.15 PRS_PLINK_1e.04 218.1 Uterine leiomyoma Female 913 8666 2 neoplasms darkcyan 8666, 913 2167, 231 2166, 239 2166, 229 2167, 214 -0.0285 0.0351 0.417 0.3801 0.972 0.907 1.04 0.029 0.0972 0.765 0.1163 1.03 0.851 1.25 -0.0143 0.0984 0.885 0.05325 0.986 0.813 1.2 -0.0805 0.0999 0.42 0.3768 0.923 0.759 1.12 PRS_PLINK_1e.04 218.2 Other benign neoplasm of uterus Female 1976 9325 2 neoplasms darkcyan 9325, 1976 2332, 500 2331, 463 2331, 507 2331, 505 0.0123 0.025 0.622 0.2065 1.01 0.964 1.06 -0.0764 0.071 0.282 0.5505 0.926 0.806 1.06 0.0199 0.0696 0.775 0.1109 1.02 0.89 1.17 0.0156 0.0699 0.824 0.08428 1.02 0.886 1.16 PRS_PLINK_1e.04 220 Benign neoplasm of ovary Female 497 4963 2 neoplasms darkcyan 4963, 497 1241, 120 1241, 134 1240, 141 1241, 102 -0.0161 0.0473 0.733 0.1348 0.984 0.897 1.08 0.119 0.132 0.366 0.4364 1.13 0.87 1.46 0.157 0.13 0.227 0.6436 1.17 0.907 1.51 -0.167 0.14 0.232 0.6354 0.846 0.643 1.11 PRS_PLINK_1e.04 221 Benign neoplasm of other female genital organs Female 1198 8167 2 neoplasms darkcyan 8167, 1198 2042, 299 2042, 303 2041, 304 2042, 292 0.00185 0.0312 0.953 0.02109 1 0.943 1.06 0.014 0.0875 0.872 0.05927 1.01 0.854 1.2 0.0151 0.0874 0.863 0.06409 1.02 0.855 1.2 -0.0296 0.0882 0.737 0.1324 0.971 0.817 1.15 PRS_PLINK_1e.04 222 Benign neoplasm of male genital organs Male 422 3651 2 neoplasms darkcyan 3651, 422 913, 113 913, 118 912, 84 913, 107 -0.0653 0.0494 0.186 0.73 0.937 0.85 1.03 0.031 0.14 0.824 0.08406 1.03 0.785 1.36 -0.296 0.151 0.0494 1.307 0.744 0.553 0.999 -0.063 0.142 0.658 0.1816 0.939 0.71 1.24 PRS_PLINK_1e.04 223 Benign neoplasm of kidney and other urinary organs Both 601 5985 2 neoplasms darkcyan 5985, 601 1497, 139 1496, 157 1496, 147 1496, 158 0.0346 0.043 0.42 0.3764 1.04 0.952 1.13 0.123 0.122 0.314 0.5029 1.13 0.89 1.44 0.0642 0.124 0.605 0.2181 1.07 0.836 1.36 0.13 0.122 0.287 0.5419 1.14 0.896 1.45 PRS_PLINK_1e.04 224 Benign neoplasm of eye Both 212 2502 2 neoplasms darkcyan 2502, 212 626, 52 625, 51 625, 55 626, 54 -0.0366 0.0718 0.611 0.2143 0.964 0.837 1.11 -0.014 0.201 0.945 0.02467 0.986 0.664 1.46 0.0609 0.198 0.759 0.1197 1.06 0.72 1.57 0.0592 0.2 0.768 0.1148 1.06 0.717 1.57 PRS_PLINK_1e.04 224.1 Benign neoplasm of eye, uveal Both 163 1995 2 neoplasms darkcyan 1995, 163 499, 38 499, 40 498, 41 499, 44 -0.0235 0.082 0.775 0.1108 0.977 0.832 1.15 0.0433 0.23 0.851 0.07031 1.04 0.666 1.64 0.0755 0.229 0.742 0.1297 1.08 0.688 1.69 0.171 0.227 0.451 0.3461 1.19 0.761 1.85 PRS_PLINK_1e.04 225 Benign neoplasm of brain and other parts of nervous system Both 532 5928 2 neoplasms darkcyan 5928, 532 1482, 127 1482, 127 1482, 147 1482, 131 0.0174 0.0451 0.699 0.1553 1.02 0.931 1.11 0.00104 0.13 0.994 0.002791 1 0.776 1.29 0.151 0.126 0.23 0.6386 1.16 0.909 1.49 0.0391 0.129 0.762 0.118 1.04 0.807 1.34 PRS_PLINK_1e.04 225.1 Benign neoplasm of brain, cranial nerves, meninges Both 426 4627 2 neoplasms darkcyan 4627, 426 1157, 103 1157, 108 1156, 115 1157, 100 0.00467 0.0503 0.926 0.03333 1 0.91 1.11 0.0481 0.143 0.737 0.1328 1.05 0.793 1.39 0.116 0.141 0.412 0.3853 1.12 0.851 1.48 -0.0235 0.146 0.872 0.05956 0.977 0.734 1.3 PRS_PLINK_1e.04 225.2 Benign neoplasm of spinal cord, meninges Both 116 1443 2 neoplasms darkcyan 1443, 116 361, 26 361, 20 360, 37 361, 33 0.0424 0.0982 0.666 0.1765 1.04 0.861 1.26 -0.236 0.295 0.424 0.3723 0.79 0.443 1.41 0.371 0.26 0.153 0.8161 1.45 0.871 2.41 0.246 0.266 0.357 0.4478 1.28 0.758 2.15 PRS_PLINK_1e.04 226 Benign neoplasm of thyroid glands Both 599 6462 2 neoplasms darkcyan 6462, 599 1616, 155 1615, 148 1615, 160 1616, 136 -0.0267 0.0421 0.526 0.2787 0.974 0.896 1.06 -0.0484 0.12 0.686 0.1636 0.953 0.754 1.2 0.0237 0.118 0.84 0.07551 1.02 0.813 1.29 -0.134 0.122 0.273 0.5638 0.875 0.689 1.11 PRS_PLINK_1e.04 227 Benign neoplasm of other endocrine glands and related structures Both 602 8045 2 neoplasms darkcyan 8045, 602 2012, 160 2011, 156 2011, 145 2011, 141 -0.0257 0.042 0.54 0.2676 0.975 0.898 1.06 -0.0133 0.116 0.909 0.04133 0.987 0.786 1.24 -0.0964 0.118 0.415 0.3818 0.908 0.72 1.15 -0.125 0.119 0.297 0.5276 0.883 0.699 1.12 PRS_PLINK_1e.04 227.1 Benign neoplasm of adrenal gland Both 103 2062 2 neoplasms darkcyan 2062, 103 516, 31 515, 21 515, 25 516, 26 -0.0652 0.103 0.527 0.2785 0.937 0.766 1.15 -0.391 0.28 0.162 0.7903 0.676 0.391 1.17 -0.194 0.268 0.469 0.329 0.823 0.487 1.39 -0.169 0.266 0.524 0.281 0.844 0.501 1.42 PRS_PLINK_1e.04 227.2 Benign neoplasm of parathyroid gland Both 320 3797 2 neoplasms darkcyan 3797, 320 950, 75 949, 96 949, 75 949, 74 0.0235 0.0578 0.684 0.1649 1.02 0.914 1.15 0.26 0.16 0.104 0.984 1.3 0.948 1.77 -0.00538 0.168 0.974 0.01122 0.995 0.715 1.38 -0.00611 0.169 0.971 0.01271 0.994 0.714 1.38 PRS_PLINK_1e.04 227.3 Benign neoplasm of pituitary gland and craniopharyngeal duct (pouch) Both 178 2164 2 neoplasms darkcyan 2164, 178 541, 50 541, 42 541, 46 541, 40 -0.0543 0.078 0.486 0.3132 0.947 0.813 1.1 -0.162 0.214 0.449 0.3473 0.85 0.559 1.29 -0.0847 0.21 0.687 0.1632 0.919 0.609 1.39 -0.206 0.218 0.345 0.4627 0.814 0.531 1.25 PRS_PLINK_1e.04 228 Hemangioma and lymphangioma, any site Both 911 8904 2 neoplasms darkcyan 8904, 911 2226, 232 2226, 243 2226, 213 2226, 223 -0.0154 0.0347 0.656 0.1828 0.985 0.92 1.05 0.0405 0.0965 0.674 0.1712 1.04 0.862 1.26 -0.0885 0.0992 0.373 0.4288 0.915 0.754 1.11 -0.0341 0.0982 0.728 0.1378 0.966 0.797 1.17 PRS_PLINK_1e.04 228.1 Hemangioma of skin and subcutaneous tissue Both 557 5326 2 neoplasms darkcyan 5326, 557 1332, 143 1331, 146 1331, 137 1332, 131 -0.0251 0.0443 0.57 0.2439 0.975 0.894 1.06 0.0239 0.123 0.846 0.07245 1.02 0.804 1.3 -0.0391 0.125 0.754 0.1224 0.962 0.753 1.23 -0.0846 0.126 0.503 0.2984 0.919 0.717 1.18 PRS_PLINK_1e.04 229 Benign neoplasm of unspecified sites Both 3513 18275 2 neoplasms darkcyan 18275, 3513 4568, 874 4569, 871 4568, 876 4569, 892 0.0181 0.0186 0.33 0.4809 1.02 0.982 1.06 0.000494 0.0528 0.993 0.003254 1 0.902 1.11 -0.000908 0.0527 0.986 0.006005 0.999 0.901 1.11 0.0145 0.0527 0.783 0.1064 1.01 0.915 1.12 PRS_PLINK_1e.04 229.1 Benign neoplasm of lymph nodes Both 2571 16673 2 neoplasms darkcyan 16673, 2571 4168, 652 4168, 621 4168, 651 4168, 647 0.0205 0.0214 0.337 0.4724 1.02 0.979 1.06 -0.0472 0.0607 0.436 0.36 0.954 0.847 1.07 -0.00139 0.06 0.982 0.008088 0.999 0.888 1.12 -0.00729 0.0602 0.904 0.04402 0.993 0.882 1.12 PRS_PLINK_1e.04 240 Simple and unspecified goiter Both 469 5093 3 endocrine/metabolic brown 5093, 469 1274, 111 1273, 124 1273, 114 1273, 120 0.00489 0.0478 0.918 0.03693 1 0.915 1.1 0.129 0.136 0.345 0.4626 1.14 0.871 1.48 0.0157 0.138 0.91 0.04114 1.02 0.775 1.33 0.0741 0.137 0.589 0.2301 1.08 0.823 1.41 PRS_PLINK_1e.04 241 Nontoxic nodular goiter Both 1277 11488 3 endocrine/metabolic brown 11488, 1277 2871, 311 2872, 329 2872, 324 2872, 313 -0.00293 0.0296 0.921 0.03562 0.997 0.941 1.06 0.063 0.0834 0.451 0.3463 1.06 0.904 1.25 0.0388 0.0837 0.643 0.192 1.04 0.882 1.22 0.00914 0.0845 0.914 0.0391 1.01 0.855 1.19 PRS_PLINK_1e.04 241.1 Nontoxic uninodular goiter Both 981 10098 3 endocrine/metabolic brown 10098, 981 2524, 234 2524, 258 2524, 242 2525, 247 0.00537 0.0335 0.873 0.0591 1.01 0.941 1.07 0.103 0.0944 0.276 0.5598 1.11 0.921 1.33 0.0323 0.0957 0.736 0.1332 1.03 0.856 1.25 0.052 0.0954 0.586 0.2323 1.05 0.874 1.27 PRS_PLINK_1e.04 241.2 Nontoxic multinodular goiter Both 536 6158 3 endocrine/metabolic brown 6158, 536 1540, 142 1539, 143 1539, 137 1540, 114 -0.0675 0.0449 0.133 0.8766 0.935 0.856 1.02 0.00692 0.123 0.955 0.01987 1.01 0.791 1.28 -0.0343 0.124 0.783 0.1065 0.966 0.757 1.23 -0.216 0.13 0.0963 1.017 0.805 0.624 1.04 PRS_PLINK_1e.04 242 Thyrotoxicosis with or without goiter Both 539 6564 3 endocrine/metabolic brown 6564, 539 1641, 132 1641, 130 1641, 145 1641, 132 -0.0169 0.0444 0.703 0.1527 0.983 0.901 1.07 -0.0099 0.128 0.938 0.02767 0.99 0.771 1.27 0.107 0.125 0.39 0.4085 1.11 0.871 1.42 0.00351 0.127 0.978 0.009642 1 0.782 1.29 PRS_PLINK_1e.04 242.1 Graves' disease Both 231 2687 3 endocrine/metabolic brown 2687, 231 672, 59 672, 54 671, 61 672, 57 -0.041 0.0672 0.541 0.2665 0.96 0.841 1.09 -0.0886 0.194 0.647 0.1888 0.915 0.626 1.34 0.0622 0.188 0.741 0.13 1.06 0.736 1.54 -0.0233 0.191 0.903 0.04438 0.977 0.672 1.42 PRS_PLINK_1e.04 242.2 Toxic multinodular goiter Both 45 569 3 endocrine/metabolic brown 569, 45 143, 12 142, 12 142, 8 142, 13 -0.0286 0.153 0.852 0.06952 0.972 0.719 1.31 0.0697 0.406 0.864 0.06357 1.07 0.483 2.38 -0.444 0.446 0.319 0.4956 0.641 0.268 1.54 0.0747 0.399 0.852 0.06976 1.08 0.493 2.36 PRS_PLINK_1e.04 242.3 Exophthalmos Both 129 1464 3 endocrine/metabolic brown 1464, 129 366, 29 366, 30 366, 40 366, 30 0.0254 0.09 0.778 0.1091 1.03 0.86 1.22 0.0246 0.266 0.926 0.03324 1.02 0.609 1.73 0.281 0.252 0.265 0.5773 1.32 0.808 2.17 0.08 0.265 0.763 0.1173 1.08 0.644 1.82 PRS_PLINK_1e.04 242.31 Thyrotoxic exophthalmos Both 71 748 3 endocrine/metabolic brown 748, 71 187, 13 187, 14 187, 27 187, 17 0.0648 0.122 0.595 0.2256 1.07 0.84 1.35 0.115 0.378 0.762 0.1182 1.12 0.535 2.35 0.658 0.344 0.0556 1.255 1.93 0.984 3.79 0.256 0.369 0.488 0.312 1.29 0.627 2.66 PRS_PLINK_1e.04 244 Hypothyroidism Both 3226 16531 3 endocrine/metabolic brown 16531, 3226 4132, 794 4133, 836 4132, 833 4133, 763 -0.0125 0.0198 0.527 0.2786 0.988 0.95 1.03 0.046 0.0556 0.408 0.389 1.05 0.939 1.17 0.0386 0.0557 0.488 0.3119 1.04 0.932 1.16 -0.0522 0.0567 0.357 0.4471 0.949 0.849 1.06 PRS_PLINK_1e.04 244.1 Secondary hypothyroidism Both 769 8789 3 endocrine/metabolic brown 8789, 769 2197, 202 2197, 204 2197, 195 2197, 168 -0.0612 0.037 0.0978 1.01 0.941 0.875 1.01 0.0183 0.104 0.86 0.06565 1.02 0.831 1.25 -0.0315 0.104 0.763 0.1176 0.969 0.79 1.19 -0.182 0.108 0.0941 1.027 0.834 0.674 1.03 PRS_PLINK_1e.04 244.2 Acquired hypothyroidism Both 497 6018 3 endocrine/metabolic brown 6018, 497 1505, 122 1504, 138 1504, 126 1505, 111 -0.0285 0.047 0.545 0.2637 0.972 0.886 1.07 0.143 0.129 0.269 0.5708 1.15 0.896 1.49 0.032 0.132 0.808 0.09262 1.03 0.798 1.34 -0.0805 0.136 0.553 0.2576 0.923 0.707 1.2 PRS_PLINK_1e.04 244.4 Hypothyroidism NOS Both 2941 16198 3 endocrine/metabolic brown 16198, 2941 4049, 731 4049, 759 4049, 758 4050, 693 -0.0164 0.0206 0.426 0.371 0.984 0.945 1.02 0.0325 0.0578 0.575 0.2406 1.03 0.922 1.16 0.031 0.0578 0.592 0.228 1.03 0.921 1.16 -0.0568 0.0589 0.335 0.4746 0.945 0.842 1.06 PRS_PLINK_1e.04 245 Thyroiditis Both 406 4452 3 endocrine/metabolic brown 4452, 406 1112, 96 1113, 109 1113, 102 1113, 99 0.0172 0.0521 0.741 0.1303 1.02 0.919 1.13 0.143 0.145 0.327 0.4861 1.15 0.867 1.53 0.0639 0.147 0.664 0.1776 1.07 0.799 1.42 0.04 0.148 0.787 0.1039 1.04 0.778 1.39 PRS_PLINK_1e.04 245.2 Chronic thyroiditis Both 332 3722 3 endocrine/metabolic brown 3722, 332 931, 76 930, 85 930, 86 931, 85 0.0501 0.0574 0.383 0.4167 1.05 0.939 1.18 0.139 0.163 0.396 0.4018 1.15 0.834 1.58 0.125 0.163 0.444 0.3524 1.13 0.823 1.56 0.122 0.163 0.453 0.3439 1.13 0.821 1.56 PRS_PLINK_1e.04 245.21 Chronic lymphocytic thyroiditis Both 330 3698 3 endocrine/metabolic brown 3698, 330 925, 76 924, 85 924, 86 925, 83 0.0365 0.0576 0.526 0.2786 1.04 0.926 1.16 0.141 0.163 0.387 0.4123 1.15 0.836 1.59 0.134 0.163 0.411 0.386 1.14 0.831 1.57 0.0998 0.164 0.543 0.2653 1.11 0.801 1.52 PRS_PLINK_1e.04 246 Other disorders of thyroid Both 2433 14991 3 endocrine/metabolic brown 14991, 2433 3747, 607 3748, 633 3747, 636 3748, 557 -0.0383 0.0223 0.0862 1.065 0.962 0.921 1.01 0.0383 0.0626 0.54 0.2673 1.04 0.919 1.17 0.0452 0.0624 0.468 0.3293 1.05 0.926 1.18 -0.106 0.0644 0.0991 1.004 0.899 0.793 1.02 PRS_PLINK_1e.04 246.2 Thyroid cyst Both 39 457 3 endocrine/metabolic brown 457, 39 115, 11 114, 8 114, 8 114, 12 -0.0138 0.156 0.929 0.03187 0.986 0.727 1.34 -0.281 0.463 0.544 0.2643 0.755 0.305 1.87 -0.416 0.479 0.385 0.4148 0.659 0.258 1.69 0.119 0.429 0.781 0.1076 1.13 0.486 2.61 PRS_PLINK_1e.04 246.7 Abnormal results of function study of thyroid Both 339 4237 3 endocrine/metabolic brown 4237, 339 1059, 87 1059, 75 1059, 89 1059, 88 0.0227 0.0564 0.688 0.1626 1.02 0.916 1.14 -0.17 0.163 0.296 0.528 0.844 0.614 1.16 0.0372 0.156 0.811 0.09083 1.04 0.765 1.41 0.0142 0.156 0.927 0.03279 1.01 0.747 1.38 PRS_PLINK_1e.04 249 Secondary diabetes mellitus Both 115 4112 3 endocrine/metabolic brown 4112, 115 1028, 30 1028, 35 1028, 29 1028, 21 -0.123 0.102 0.228 0.6421 0.884 0.724 1.08 0.297 0.263 0.259 0.5865 1.35 0.803 2.26 0.0962 0.28 0.731 0.1359 1.1 0.636 1.91 -0.102 0.304 0.738 0.1318 0.903 0.498 1.64 PRS_PLINK_1e.04 250 Diabetes mellitus Both 3324 19213 3 endocrine/metabolic brown 19213, 3324 4803, 825 4803, 810 4803, 838 4803, 851 0.0307 0.0202 0.128 0.8915 1.03 0.991 1.07 0.0148 0.0572 0.795 0.09948 1.01 0.907 1.14 0.0158 0.0572 0.782 0.1066 1.02 0.908 1.14 0.0533 0.0568 0.348 0.4586 1.05 0.944 1.18 PRS_PLINK_1e.04 250.1 Type 1 diabetes Both 535 6158 3 endocrine/metabolic brown 6158, 535 1540, 143 1539, 138 1539, 123 1540, 131 0.0161 0.0715 0.822 0.08516 1.02 0.883 1.17 0.277 0.188 0.141 0.8504 1.32 0.912 1.91 -0.154 0.205 0.453 0.344 0.858 0.574 1.28 0.19 0.198 0.337 0.4718 1.21 0.821 1.78 PRS_PLINK_1e.04 250.11 Type 1 diabetes with ketoacidosis Both 89 603 3 endocrine/metabolic brown 603, 89 151, 27 151, 15 150, 25 151, 22 0.0815 0.179 0.648 0.1883 1.08 0.765 1.54 -0.62 0.496 0.211 0.6757 0.538 0.203 1.42 -0.106 0.471 0.821 0.08548 0.899 0.357 2.26 0.0993 0.448 0.825 0.08376 1.1 0.459 2.66 PRS_PLINK_1e.04 250.12 Type 1 diabetes with renal manifestations Both 63 1484 3 endocrine/metabolic brown 1484, 63 371, 17 371, 19 371, 14 371, 13 0.107 0.174 0.538 0.2694 1.11 0.792 1.56 0.496 0.42 0.237 0.6244 1.64 0.721 3.74 0.00934 0.442 0.983 0.007385 1.01 0.425 2.4 0.409 0.476 0.39 0.4094 1.51 0.593 3.82 PRS_PLINK_1e.04 250.13 Type 1 diabetes with ophthalmic manifestations Both 144 1632 3 endocrine/metabolic brown 1632, 144 408, 32 408, 34 408, 38 408, 40 0.242 0.134 0.0697 1.157 1.27 0.981 1.66 0.457 0.355 0.197 0.7046 1.58 0.788 3.17 0.321 0.354 0.364 0.4388 1.38 0.689 2.76 0.862 0.373 0.0209 1.679 2.37 1.14 4.92 PRS_PLINK_1e.04 250.14 Type 1 diabetes with neurological manifestations Both 83 1444 3 endocrine/metabolic brown 1444, 83 361, 19 361, 20 361, 21 361, 23 0.225 0.151 0.137 0.8634 1.25 0.931 1.68 0.542 0.399 0.174 0.759 1.72 0.787 3.75 0.344 0.426 0.419 0.3778 1.41 0.612 3.25 0.829 0.439 0.0586 1.232 2.29 0.97 5.42 PRS_PLINK_1e.04 250.15 Diabetes type 1 with peripheral circulatory disorders Both 6 444 3 endocrine/metabolic brown 444, 6 111, 2 111, 0 111, 0 111, 4 0.473 0.369 0.2 0.6991 1.61 0.778 3.31 -1.82 1.14 0.11 0.9571 0.163 0.0175 1.51 -1.03 1 0.304 0.5176 0.358 0.0504 2.54 1.19 0.825 0.148 0.8283 3.29 0.654 16.6 PRS_PLINK_1e.04 250.2 Type 2 diabetes Both 1795 17250 3 endocrine/metabolic brown 17250, 1795 4312, 457 4312, 453 4312, 431 4313, 454 0.0064 0.0275 0.816 0.0884 1.01 0.954 1.06 0.0546 0.0769 0.477 0.3213 1.06 0.908 1.23 -0.0561 0.0788 0.477 0.3215 0.945 0.81 1.1 0.0485 0.0774 0.531 0.2746 1.05 0.902 1.22 PRS_PLINK_1e.04 250.21 Type 2 diabetes with ketoacidosis Both 65 757 3 endocrine/metabolic brown 757, 65 190, 18 189, 15 189, 15 189, 17 0.0236 0.175 0.893 0.0493 1.02 0.727 1.44 -0.319 0.469 0.497 0.3041 0.727 0.29 1.82 -0.33 0.445 0.458 0.339 0.719 0.301 1.72 -0.0298 0.459 0.948 0.02305 0.971 0.395 2.39 PRS_PLINK_1e.04 250.22 Type 2 diabetes with renal manifestations Both 70 5998 3 endocrine/metabolic brown 5998, 70 1500, 17 1499, 16 1499, 19 1500, 18 0.0533 0.129 0.68 0.1676 1.05 0.819 1.36 0.0777 0.347 0.823 0.08485 1.08 0.548 2.13 0.00123 0.36 0.997 0.001186 1 0.494 2.03 0.171 0.361 0.636 0.1962 1.19 0.584 2.41 PRS_PLINK_1e.04 250.23 Type 2 diabetes with ophthalmic manifestations Both 144 4482 3 endocrine/metabolic brown 4482, 144 1121, 37 1120, 35 1120, 42 1121, 30 0.000464 0.103 0.996 0.001566 1 0.818 1.22 0.115 0.271 0.671 0.1734 1.12 0.66 1.91 0.0898 0.276 0.745 0.1279 1.09 0.637 1.88 0.0456 0.286 0.873 0.05885 1.05 0.597 1.83 PRS_PLINK_1e.04 250.24 Type 2 diabetes with neurological manifestations Both 189 7656 3 endocrine/metabolic brown 7656, 189 1914, 52 1914, 48 1914, 47 1914, 42 0.0238 0.0819 0.771 0.1129 1.02 0.872 1.2 0.0613 0.221 0.781 0.1073 1.06 0.69 1.64 0.0163 0.222 0.942 0.02617 1.02 0.657 1.57 -0.0316 0.232 0.892 0.04977 0.969 0.614 1.53 PRS_PLINK_1e.04 250.25 Diabetes type 2 with peripheral circulatory disorders Both 17 2504 3 endocrine/metabolic brown 2504, 17 626, 3 626, 7 626, 4 626, 3 -0.152 0.222 0.494 0.3067 0.859 0.557 1.33 0.857 0.59 0.146 0.8349 2.36 0.742 7.48 0.291 0.61 0.634 0.1981 1.34 0.405 4.42 0.264 0.68 0.698 0.1563 1.3 0.343 4.94 PRS_PLINK_1e.04 250.3 Insulin pump user Both 545 10572 3 endocrine/metabolic brown 10572, 545 2643, 141 2643, 141 2643, 134 2643, 129 0.0148 0.0611 0.808 0.09246 1.01 0.9 1.14 0.227 0.166 0.171 0.7664 1.26 0.906 1.74 0.0814 0.171 0.634 0.1981 1.08 0.776 1.52 0.107 0.176 0.541 0.2668 1.11 0.789 1.57 PRS_PLINK_1e.04 250.4 Abnormal glucose Both 2248 18142 3 endocrine/metabolic brown 18142, 2248 4535, 555 4535, 541 4535, 586 4536, 566 0.0354 0.0244 0.147 0.8333 1.04 0.988 1.09 0.00554 0.0692 0.936 0.02866 1.01 0.878 1.15 0.063 0.0683 0.357 0.4477 1.06 0.932 1.22 0.0412 0.0688 0.549 0.2601 1.04 0.911 1.19 PRS_PLINK_1e.04 250.41 Impaired fasting glucose Both 492 8065 3 endocrine/metabolic brown 8065, 492 2017, 116 2016, 125 2016, 127 2016, 124 0.0341 0.0479 0.477 0.3217 1.03 0.942 1.14 0.0818 0.135 0.545 0.2636 1.09 0.833 1.41 0.121 0.134 0.368 0.4345 1.13 0.868 1.47 0.0951 0.136 0.483 0.3157 1.1 0.843 1.44 PRS_PLINK_1e.04 250.42 Other abnormal glucose Both 1978 17613 3 endocrine/metabolic brown 17613, 1978 4403, 494 4403, 481 4403, 502 4403, 501 0.0347 0.026 0.183 0.7382 1.04 0.984 1.09 0.0239 0.0734 0.744 0.1283 1.02 0.887 1.18 0.0307 0.0733 0.675 0.1704 1.03 0.893 1.19 0.0515 0.0732 0.482 0.3171 1.05 0.912 1.22 PRS_PLINK_1e.04 250.5 Glycosuria or Acetonuria Both 38 658 3 endocrine/metabolic brown 658, 38 165, 9 164, 11 164, 9 165, 9 -0.0139 0.167 0.934 0.02976 0.986 0.711 1.37 0.337 0.445 0.449 0.3476 1.4 0.585 3.35 0.203 0.467 0.663 0.1785 1.23 0.491 3.06 0.166 0.472 0.725 0.1399 1.18 0.468 2.98 PRS_PLINK_1e.04 250.6 Polyneuropathy in diabetes Both 163 6159 3 endocrine/metabolic brown 6159, 163 1540, 43 1540, 39 1539, 42 1540, 39 0.0647 0.093 0.487 0.3129 1.07 0.889 1.28 0.238 0.252 0.345 0.4621 1.27 0.774 2.08 0.163 0.258 0.527 0.2784 1.18 0.71 1.95 0.176 0.27 0.513 0.29 1.19 0.703 2.02 PRS_PLINK_1e.04 250.7 Diabetic retinopathy Both 198 4330 3 endocrine/metabolic brown 4330, 198 1083, 47 1082, 51 1082, 51 1083, 49 0.0243 0.0775 0.754 0.1226 1.02 0.88 1.19 0.23 0.216 0.289 0.5397 1.26 0.823 1.92 0.0806 0.22 0.714 0.1463 1.08 0.704 1.67 0.202 0.221 0.36 0.4434 1.22 0.794 1.89 PRS_PLINK_1e.04 251 Other disorders of pancreatic internal secretion Both 316 4168 3 endocrine/metabolic brown 4168, 316 1042, 89 1042, 75 1042, 83 1042, 69 -0.0818 0.0589 0.165 0.7822 0.922 0.821 1.03 -0.124 0.163 0.448 0.349 0.883 0.641 1.22 -0.0594 0.159 0.708 0.1499 0.942 0.691 1.29 -0.235 0.166 0.156 0.807 0.79 0.571 1.09 PRS_PLINK_1e.04 251.1 Hypoglycemia Both 390 4982 3 endocrine/metabolic brown 4982, 390 1246, 114 1245, 90 1245, 107 1246, 79 -0.0834 0.0578 0.149 0.8273 0.92 0.822 1.03 -0.231 0.16 0.15 0.8226 0.794 0.58 1.09 -0.0274 0.152 0.857 0.06688 0.973 0.722 1.31 -0.283 0.163 0.0825 1.084 0.753 0.547 1.04 PRS_PLINK_1e.04 252 Disorders of parathyroid gland Both 634 10554 3 endocrine/metabolic brown 10554, 634 2639, 155 2638, 164 2638, 173 2639, 142 0.0257 0.0407 0.527 0.2779 1.03 0.947 1.11 0.0658 0.115 0.567 0.2465 1.07 0.853 1.34 0.113 0.113 0.317 0.4985 1.12 0.897 1.4 -0.087 0.119 0.464 0.3336 0.917 0.726 1.16 PRS_PLINK_1e.04 252.1 Hyperparathyroidism Both 553 9475 3 endocrine/metabolic brown 9475, 553 2369, 137 2369, 146 2368, 147 2369, 123 0.0152 0.0436 0.727 0.1382 1.02 0.932 1.11 0.072 0.122 0.555 0.256 1.07 0.846 1.36 0.0712 0.122 0.558 0.2533 1.07 0.846 1.36 -0.11 0.127 0.387 0.4121 0.896 0.699 1.15 PRS_PLINK_1e.04 252.2 Hypoparathyroidism Both 180 2571 3 endocrine/metabolic brown 2571, 180 643, 52 643, 45 642, 43 643, 40 -0.0438 0.0758 0.563 0.2493 0.957 0.825 1.11 -0.128 0.208 0.539 0.2687 0.88 0.586 1.32 -0.196 0.21 0.35 0.4564 0.822 0.545 1.24 -0.244 0.215 0.254 0.5944 0.783 0.514 1.19 PRS_PLINK_1e.04 253 Disorders of the pituitary gland and its hypothalamic control Both 332 4279 3 endocrine/metabolic brown 4279, 332 1070, 72 1070, 110 1069, 77 1070, 73 -0.0154 0.0566 0.786 0.1044 0.985 0.881 1.1 0.429 0.156 0.00613 2.213 1.54 1.13 2.09 0.0683 0.168 0.684 0.1649 1.07 0.771 1.49 0.023 0.17 0.893 0.04936 1.02 0.733 1.43 PRS_PLINK_1e.04 253.1 Pituitary hyperfunction Both 123 1495 3 endocrine/metabolic brown 1495, 123 374, 29 374, 33 373, 31 374, 30 -0.00673 0.095 0.944 0.02522 0.993 0.824 1.2 0.156 0.259 0.546 0.2626 1.17 0.703 1.94 0.11 0.267 0.68 0.1672 1.12 0.662 1.88 0.12 0.269 0.655 0.1837 1.13 0.666 1.91 PRS_PLINK_1e.04 253.11 Acromegaly and gigantism Both 36 469 3 endocrine/metabolic brown 469, 36 118, 9 117, 12 117, 10 117, 5 -0.103 0.176 0.56 0.2522 0.902 0.639 1.27 0.233 0.44 0.597 0.2242 1.26 0.533 2.99 0.189 0.473 0.689 0.1616 1.21 0.478 3.05 -0.558 0.527 0.29 0.5382 0.572 0.204 1.61 PRS_PLINK_1e.04 253.2 Pituitary hypofunction Both 93 1136 3 endocrine/metabolic brown 1136, 93 284, 21 284, 33 284, 16 284, 23 0.0186 0.107 0.862 0.06426 1.02 0.826 1.26 0.475 0.284 0.0941 1.027 1.61 0.922 2.8 -0.214 0.33 0.517 0.2868 0.807 0.423 1.54 0.0596 0.303 0.844 0.07358 1.06 0.586 1.92 PRS_PLINK_1e.04 253.3 Diabetes insipidus Both 32 454 3 endocrine/metabolic brown 454, 32 114, 4 113, 14 113, 6 114, 8 0.096 0.172 0.576 0.2395 1.1 0.786 1.54 1.27 0.542 0.019 1.721 3.57 1.23 10.3 0.307 0.567 0.588 0.231 1.36 0.448 4.13 0.688 0.562 0.221 0.6551 1.99 0.661 5.99 PRS_PLINK_1e.04 253.4 Anterior pituitary disorders Both 35 535 3 endocrine/metabolic brown 535, 35 134, 10 134, 15 133, 2 134, 8 -0.132 0.167 0.428 0.369 0.876 0.632 1.21 0.405 0.407 0.32 0.4954 1.5 0.676 3.33 -1.32 0.639 0.0397 1.401 0.268 0.0767 0.94 -0.122 0.453 0.787 0.1041 0.885 0.364 2.15 PRS_PLINK_1e.04 253.7 Other disorders of neurohypophysis Both 19 420 3 endocrine/metabolic brown 420, 19 105, 4 105, 11 105, 2 105, 2 -0.284 0.211 0.179 0.7481 0.753 0.498 1.14 0.928 0.536 0.0833 1.079 2.53 0.885 7.23 -0.494 0.704 0.483 0.3163 0.61 0.153 2.43 -0.98 0.818 0.231 0.6367 0.375 0.0755 1.86 PRS_PLINK_1e.04 255 Disorders of adrenal glands Both 415 7178 3 endocrine/metabolic brown 7178, 415 1795, 108 1794, 102 1794, 94 1795, 111 0.00297 0.0511 0.954 0.02063 1 0.907 1.11 -0.0398 0.141 0.778 0.1091 0.961 0.729 1.27 -0.134 0.144 0.352 0.4538 0.875 0.66 1.16 0.0277 0.138 0.841 0.07513 1.03 0.784 1.35 PRS_PLINK_1e.04 255.1 Adrenal hyperfunction Both 78 2044 3 endocrine/metabolic brown 2044, 78 511, 17 511, 20 511, 18 511, 23 0.0588 0.118 0.619 0.2083 1.06 0.841 1.34 0.226 0.32 0.481 0.3179 1.25 0.669 2.35 0.0203 0.332 0.951 0.02172 1.02 0.532 1.96 0.316 0.312 0.311 0.5071 1.37 0.744 2.53 PRS_PLINK_1e.04 255.11 Cushing's syndrome Both 48 1085 3 endocrine/metabolic brown 1085, 48 272, 11 271, 13 271, 8 271, 16 0.0967 0.143 0.498 0.3026 1.1 0.833 1.46 0.29 0.396 0.464 0.3337 1.34 0.615 2.9 -0.239 0.44 0.587 0.2316 0.787 0.332 1.86 0.399 0.373 0.286 0.5443 1.49 0.717 3.1 PRS_PLINK_1e.04 255.12 Hyperaldosteronism Both 11 599 3 endocrine/metabolic brown 599, 11 150, 2 150, 2 149, 3 150, 4 0.185 0.281 0.51 0.2928 1.2 0.694 2.09 -0.164 0.752 0.828 0.0822 0.849 0.194 3.71 0.373 0.709 0.599 0.2223 1.45 0.361 5.83 1 0.739 0.176 0.7545 2.72 0.639 11.6 PRS_PLINK_1e.04 255.2 Adrenal hypofunction Both 193 3164 3 endocrine/metabolic brown 3164, 193 791, 49 791, 44 791, 49 791, 51 -0.00637 0.0749 0.932 0.03049 0.994 0.858 1.15 -0.0769 0.21 0.714 0.1464 0.926 0.614 1.4 -0.00149 0.204 0.994 0.002525 0.999 0.669 1.49 0.0264 0.203 0.897 0.0474 1.03 0.689 1.53 PRS_PLINK_1e.04 255.21 Glucocorticoid deficiency Both 180 3019 3 endocrine/metabolic brown 3019, 180 755, 41 755, 45 754, 46 755, 48 0.0418 0.0778 0.591 0.2284 1.04 0.895 1.21 0.116 0.218 0.596 0.225 1.12 0.733 1.72 0.094 0.216 0.664 0.1778 1.1 0.719 1.68 0.141 0.215 0.511 0.2912 1.15 0.755 1.76 PRS_PLINK_1e.04 256 Ovarian dysfunction Female 697 7600 3 endocrine/metabolic brown 7600, 697 1899, 168 1900, 181 1900, 179 1900, 169 0.027 0.04 0.499 0.3015 1.03 0.95 1.11 0.0803 0.112 0.473 0.3249 1.08 0.87 1.35 0.0704 0.112 0.53 0.2757 1.07 0.861 1.34 0.0193 0.113 0.865 0.06323 1.02 0.816 1.27 PRS_PLINK_1e.04 256.4 Polycystic ovaries Female 433 5474 3 endocrine/metabolic brown 5474, 433 1368, 105 1368, 115 1368, 103 1369, 110 0.0139 0.0501 0.782 0.1069 1.01 0.919 1.12 0.0981 0.14 0.483 0.3157 1.1 0.838 1.45 -0.0194 0.144 0.893 0.0492 0.981 0.74 1.3 0.0669 0.141 0.635 0.1969 1.07 0.811 1.41 PRS_PLINK_1e.04 257 Testicular dysfunction Male 289 3828 3 endocrine/metabolic brown 3828, 289 957, 76 957, 83 957, 70 957, 60 -0.0752 0.06 0.21 0.6772 0.928 0.825 1.04 0.0994 0.164 0.545 0.2635 1.1 0.801 1.52 -0.0807 0.171 0.637 0.1956 0.922 0.659 1.29 -0.227 0.176 0.198 0.7034 0.797 0.564 1.13 PRS_PLINK_1e.04 257.1 Testicular hypofunction Male 274 3675 3 endocrine/metabolic brown 3675, 274 919, 71 919, 80 918, 66 919, 57 -0.0695 0.0619 0.262 0.5825 0.933 0.826 1.05 0.142 0.168 0.399 0.399 1.15 0.829 1.6 -0.0941 0.177 0.595 0.2255 0.91 0.643 1.29 -0.221 0.182 0.224 0.6495 0.802 0.562 1.14 PRS_PLINK_1e.04 258 Iatrogenic endocrine disorders Both 28 405 3 endocrine/metabolic brown 405, 28 102, 6 101, 8 101, 8 101, 6 0.0352 0.187 0.851 0.07 1.04 0.717 1.5 0.222 0.511 0.664 0.1779 1.25 0.459 3.4 0.277 0.54 0.608 0.2163 1.32 0.458 3.8 -0.14 0.541 0.795 0.09951 0.869 0.301 2.51 PRS_PLINK_1e.04 258.1 Postablative ovarian failure Female 62 754 3 endocrine/metabolic brown 754, 62 189, 15 188, 13 188, 18 189, 16 0.0211 0.133 0.874 0.05865 1.02 0.787 1.32 -0.0965 0.378 0.798 0.09778 0.908 0.433 1.9 0.156 0.351 0.657 0.1824 1.17 0.587 2.33 0.0467 0.36 0.897 0.04736 1.05 0.518 2.12 PRS_PLINK_1e.04 259 Other endocrine disorders Both 365 5397 3 endocrine/metabolic brown 5397, 365 1350, 97 1349, 97 1349, 88 1349, 83 -0.0825 0.0544 0.129 0.8889 0.921 0.828 1.02 0.0178 0.148 0.904 0.04371 1.02 0.762 1.36 -0.0974 0.151 0.518 0.2853 0.907 0.675 1.22 -0.155 0.153 0.311 0.5072 0.856 0.634 1.16 PRS_PLINK_1e.04 260 Protein-calorie malnutrition Both 915 12534 3 endocrine/metabolic brown 12534, 915 3133, 229 3133, 216 3133, 236 3134, 234 -0.0166 0.0339 0.624 0.2045 0.984 0.92 1.05 -0.0584 0.0978 0.551 0.2592 0.943 0.779 1.14 0.0238 0.0958 0.803 0.09503 1.02 0.849 1.24 0.0197 0.0961 0.838 0.07695 1.02 0.845 1.23 PRS_PLINK_1e.04 260.1 Cachexia Both 101 1268 3 endocrine/metabolic brown 1268, 101 317, 30 317, 19 317, 27 317, 25 -0.00273 0.0993 0.978 0.009628 0.997 0.821 1.21 -0.542 0.3 0.0704 1.152 0.582 0.323 1.05 -0.0707 0.274 0.796 0.09889 0.932 0.545 1.59 -0.188 0.277 0.498 0.3032 0.829 0.481 1.43 PRS_PLINK_1e.04 260.2 severe protein-calorie malnutrition Both 536 7580 3 endocrine/metabolic brown 7580, 536 1895, 121 1895, 136 1895, 142 1895, 137 0.0193 0.0443 0.663 0.1782 1.02 0.935 1.11 0.112 0.128 0.383 0.4165 1.12 0.87 1.44 0.163 0.127 0.2 0.6989 1.18 0.917 1.51 0.11 0.128 0.39 0.4085 1.12 0.868 1.44 PRS_PLINK_1e.04 260.22 Nutritional marasmus Both 196 2835 3 endocrine/metabolic brown 2835, 196 709, 54 709, 31 708, 55 709, 56 0.00141 0.0713 0.984 0.006885 1 0.871 1.15 -0.568 0.227 0.0123 1.91 0.567 0.363 0.884 0.0168 0.196 0.931 0.03086 1.02 0.693 1.49 0.0337 0.195 0.863 0.06401 1.03 0.706 1.52 PRS_PLINK_1e.04 260.3 Adult failure to thrive Both 150 2552 3 endocrine/metabolic brown 2552, 150 638, 39 638, 35 638, 36 638, 40 -0.0188 0.0809 0.817 0.08801 0.981 0.837 1.15 -0.122 0.235 0.604 0.219 0.885 0.558 1.4 -0.0861 0.234 0.713 0.1467 0.917 0.58 1.45 0.0243 0.229 0.915 0.03843 1.02 0.654 1.6 PRS_PLINK_1e.04 260.6 Anorexia Both 286 3883 3 endocrine/metabolic brown 3883, 286 971, 68 971, 64 970, 82 971, 72 0.0644 0.0622 0.301 0.5221 1.07 0.944 1.2 -0.0535 0.178 0.763 0.1172 0.948 0.669 1.34 0.196 0.168 0.244 0.6118 1.22 0.875 1.69 0.0749 0.173 0.666 0.1766 1.08 0.767 1.51 PRS_PLINK_1e.04 260.7 Polyphagia Both 33 385 3 endocrine/metabolic brown 385, 33 97, 8 96, 6 96, 13 96, 6 -0.079 0.173 0.648 0.1884 0.924 0.658 1.3 -0.234 0.5 0.64 0.1939 0.791 0.297 2.11 0.441 0.442 0.318 0.4974 1.56 0.654 3.7 -0.336 0.517 0.515 0.2878 0.715 0.26 1.97 PRS_PLINK_1e.04 261 Vitamin deficiency Both 2863 19005 3 endocrine/metabolic brown 19005, 2863 4751, 710 4751, 723 4751, 697 4751, 733 0.0195 0.0205 0.342 0.4659 1.02 0.98 1.06 0.028 0.0577 0.627 0.2027 1.03 0.918 1.15 -0.027 0.0583 0.643 0.1915 0.973 0.868 1.09 0.0395 0.0575 0.493 0.3076 1.04 0.929 1.16 PRS_PLINK_1e.04 261.1 Vitamin A deficiency Both 24 394 3 endocrine/metabolic brown 394, 24 99, 8 98, 4 98, 6 99, 6 -0.0485 0.21 0.817 0.08753 0.953 0.631 1.44 -0.35 0.565 0.535 0.2717 0.705 0.233 2.13 -0.0348 0.53 0.948 0.02333 0.966 0.341 2.73 -0.103 0.512 0.841 0.07507 0.903 0.331 2.46 PRS_PLINK_1e.04 261.2 Vitamin B-complex deficiencies Both 271 3936 3 endocrine/metabolic brown 3936, 271 984, 69 984, 59 984, 67 984, 76 0.06 0.063 0.341 0.4677 1.06 0.939 1.2 -0.157 0.181 0.387 0.4127 0.855 0.6 1.22 -0.0527 0.175 0.763 0.1172 0.949 0.673 1.34 0.099 0.17 0.561 0.2511 1.1 0.791 1.54 PRS_PLINK_1e.04 261.4 Vitamin D deficiency Both 2719 19039 3 endocrine/metabolic brown 19039, 2719 4759, 672 4760, 686 4759, 669 4760, 692 0.0215 0.021 0.305 0.5156 1.02 0.981 1.06 0.0321 0.0591 0.587 0.2312 1.03 0.92 1.16 -0.0102 0.0595 0.864 0.06343 0.99 0.881 1.11 0.0388 0.059 0.51 0.2921 1.04 0.926 1.17 PRS_PLINK_1e.04 261.41 Rickets or osteomalacia Both 12 265 3 endocrine/metabolic brown 265, 12 67, 3 66, 2 66, 2 66, 5 0.214 0.289 0.459 0.3378 1.24 0.703 2.18 -0.304 0.799 0.703 0.153 0.738 0.154 3.53 -0.789 0.816 0.333 0.4773 0.454 0.0918 2.25 0.235 0.668 0.725 0.1395 1.26 0.341 4.69 PRS_PLINK_1e.04 262 Mineral deficiency NEC Both 383 6300 3 endocrine/metabolic brown 6300, 383 1575, 90 1575, 95 1575, 103 1575, 95 0.0569 0.0526 0.279 0.5538 1.06 0.955 1.17 0.0491 0.15 0.744 0.1287 1.05 0.783 1.41 0.143 0.148 0.333 0.4774 1.15 0.864 1.54 0.0688 0.15 0.647 0.1888 1.07 0.798 1.44 PRS_PLINK_1e.04 263 Other nutritional deficiency Both 551 7967 3 endocrine/metabolic brown 7967, 551 1991, 130 1992, 156 1991, 144 1992, 121 -0.0293 0.0435 0.501 0.3003 0.971 0.892 1.06 0.192 0.123 0.117 0.93 1.21 0.953 1.54 0.105 0.124 0.399 0.3989 1.11 0.87 1.42 -0.0614 0.129 0.635 0.1969 0.94 0.73 1.21 PRS_PLINK_1e.04 264 Lack of normal physiological development Both 131 1506 3 endocrine/metabolic brown 1506, 131 377, 33 376, 40 376, 29 377, 29 -0.0146 0.0907 0.872 0.05966 0.985 0.825 1.18 0.226 0.244 0.355 0.4499 1.25 0.777 2.02 -0.168 0.259 0.516 0.287 0.845 0.509 1.4 -0.12 0.26 0.644 0.1911 0.887 0.532 1.48 PRS_PLINK_1e.04 264.2 Failure to thrive (childhood) Both 50 621 3 endocrine/metabolic brown 621, 50 156, 10 155, 19 155, 8 155, 13 0.112 0.14 0.423 0.3732 1.12 0.85 1.47 0.663 0.391 0.0901 1.045 1.94 0.902 4.18 -0.134 0.451 0.767 0.1153 0.875 0.362 2.12 0.406 0.419 0.332 0.4785 1.5 0.661 3.41 PRS_PLINK_1e.04 264.9 Lack of normal physiological development, unspecified Both 57 618 3 endocrine/metabolic brown 618, 57 155, 13 154, 17 154, 12 155, 15 0.0085 0.137 0.951 0.02204 1.01 0.771 1.32 0.292 0.38 0.442 0.3549 1.34 0.636 2.82 -0.104 0.404 0.797 0.09855 0.901 0.408 1.99 0.104 0.382 0.786 0.1047 1.11 0.524 2.35 PRS_PLINK_1e.04 269 Proteinuria Both 196 6241 3 endocrine/metabolic brown 6241, 196 1561, 45 1560, 39 1560, 56 1560, 56 0.0722 0.0736 0.326 0.4862 1.07 0.931 1.24 -0.0798 0.219 0.715 0.1457 0.923 0.602 1.42 0.218 0.201 0.278 0.5552 1.24 0.838 1.84 0.248 0.201 0.217 0.6625 1.28 0.864 1.9 PRS_PLINK_1e.04 270 Disorders of protein plasma/amino-acid transport and metabolism Both 268 4171 3 endocrine/metabolic brown 4171, 268 1043, 68 1043, 71 1042, 60 1043, 69 0.0228 0.0625 0.716 0.1452 1.02 0.905 1.16 0.0438 0.173 0.8 0.09703 1.04 0.745 1.47 -0.116 0.18 0.519 0.285 0.891 0.626 1.27 0.0128 0.174 0.941 0.0262 1.01 0.72 1.43 PRS_PLINK_1e.04 270.1 Disturbances of amino-acid transport Both 68 959 3 endocrine/metabolic brown 959, 68 240, 22 240, 12 239, 15 240, 19 -0.105 0.123 0.396 0.4026 0.9 0.707 1.15 -0.61 0.355 0.0857 1.067 0.543 0.271 1.09 -0.393 0.337 0.243 0.6148 0.675 0.349 1.31 -0.18 0.315 0.568 0.2456 0.835 0.45 1.55 PRS_PLINK_1e.04 270.11 Disturbances of sulphur-bearing amino-acid metabolism Both 60 782 3 endocrine/metabolic brown 782, 60 196, 21 195, 11 195, 14 196, 14 -0.208 0.129 0.108 0.9667 0.812 0.63 1.05 -0.652 0.367 0.0757 1.121 0.521 0.254 1.07 -0.441 0.348 0.205 0.6887 0.644 0.326 1.27 -0.455 0.347 0.19 0.7219 0.634 0.321 1.25 PRS_PLINK_1e.04 270.2 Disorders of amino-acid metabolism Both 27 440 3 endocrine/metabolic brown 440, 27 110, 5 110, 5 110, 8 110, 9 0.0359 0.184 0.846 0.07277 1.04 0.722 1.49 -0.0627 0.555 0.91 0.04096 0.939 0.317 2.79 0.276 0.516 0.592 0.2274 1.32 0.48 3.62 0.386 0.524 0.461 0.3364 1.47 0.527 4.1 PRS_PLINK_1e.04 270.3 Disorders of plasma protein metabolism Both 180 2914 3 endocrine/metabolic brown 2914, 180 729, 43 728, 55 728, 38 729, 44 0.0541 0.076 0.477 0.3216 1.06 0.909 1.23 0.25 0.206 0.224 0.65 1.28 0.858 1.92 -0.103 0.223 0.645 0.1907 0.902 0.583 1.4 0.0361 0.216 0.868 0.06171 1.04 0.679 1.58 PRS_PLINK_1e.04 270.32 Paraproteinemia Both 72 1286 3 endocrine/metabolic brown 1286, 72 322, 19 321, 18 321, 23 322, 12 -0.0806 0.117 0.49 0.3095 0.923 0.734 1.16 -0.0229 0.322 0.943 0.02532 0.977 0.52 1.84 0.226 0.308 0.462 0.3353 1.25 0.686 2.29 -0.477 0.361 0.186 0.7303 0.621 0.306 1.26 PRS_PLINK_1e.04 270.33 Amyloidosis Both 22 281 3 endocrine/metabolic brown 281, 22 71, 4 70, 6 70, 9 70, 3 0.0542 0.194 0.779 0.1083 1.06 0.722 1.54 0.703 0.615 0.253 0.5977 2.02 0.606 6.74 0.907 0.591 0.125 0.9044 2.48 0.778 7.88 -0.0363 0.69 0.958 0.0186 0.964 0.249 3.73 PRS_PLINK_1e.04 270.34 Alpha-1-antitrypsin deficiency Both 28 324 3 endocrine/metabolic brown 324, 28 81, 4 81, 8 81, 6 81, 10 0.492 0.202 0.0149 1.826 1.64 1.1 2.43 0.611 0.565 0.279 0.5536 1.84 0.609 5.57 0.456 0.594 0.443 0.3539 1.58 0.492 5.06 0.944 0.583 0.106 0.9762 2.57 0.819 8.06 PRS_PLINK_1e.04 270.38 Other specified disorders of plasma protein metabolism Both 85 1392 3 endocrine/metabolic brown 1392, 85 348, 18 348, 26 348, 14 348, 27 0.144 0.11 0.189 0.7226 1.16 0.931 1.43 0.355 0.306 0.245 0.6101 1.43 0.783 2.6 -0.208 0.342 0.543 0.265 0.812 0.415 1.59 0.403 0.305 0.187 0.7286 1.5 0.822 2.72 PRS_PLINK_1e.04 271 Disorders of carbohydrate transport and metabolism Both 979 12425 3 endocrine/metabolic brown 12425, 979 3106, 255 3106, 228 3106, 247 3106, 249 0.0104 0.0335 0.757 0.121 1.01 0.946 1.08 -0.118 0.0944 0.212 0.673 0.889 0.739 1.07 -0.0326 0.0927 0.725 0.1398 0.968 0.807 1.16 -0.0248 0.0925 0.789 0.1032 0.975 0.814 1.17 PRS_PLINK_1e.04 271.3 Intestinal disaccharidase deficiencies and disaccharide malabsorption Both 940 12039 3 endocrine/metabolic brown 12039, 940 3009, 247 3010, 219 3009, 236 3010, 238 0.0119 0.0341 0.727 0.1383 1.01 0.947 1.08 -0.126 0.0961 0.188 0.7252 0.881 0.73 1.06 -0.0462 0.0945 0.625 0.2042 0.955 0.794 1.15 -0.0364 0.0942 0.7 0.1551 0.964 0.802 1.16 PRS_PLINK_1e.04 271.9 Other disorders of carbohydrate transport and metabolism Both 47 497 3 endocrine/metabolic brown 497, 47 125, 13 124, 10 124, 12 124, 12 -0.121 0.15 0.42 0.377 0.886 0.661 1.19 -0.181 0.413 0.661 0.18 0.834 0.371 1.87 -0.0245 0.402 0.951 0.02163 0.976 0.444 2.14 -0.126 0.406 0.756 0.1215 0.881 0.398 1.95 PRS_PLINK_1e.04 272 Disorders of lipoid metabolism Both 4703 17608 3 endocrine/metabolic brown 17608, 4703 4401, 1111 4402, 1189 4402, 1244 4402, 1159 0.03 0.0174 0.0844 1.074 1.03 0.996 1.07 0.0803 0.0498 0.107 0.9718 1.08 0.983 1.19 0.114 0.0493 0.0209 1.68 1.12 1.02 1.23 0.0441 0.0499 0.377 0.4239 1.05 0.948 1.15 PRS_PLINK_1e.04 272.1 Hyperlipidemia Both 4678 17592 3 endocrine/metabolic brown 17592, 4678 4397, 1106 4398, 1184 4398, 1231 4398, 1157 0.0295 0.0174 0.0896 1.048 1.03 0.995 1.07 0.082 0.0498 0.0998 1.001 1.09 0.984 1.2 0.109 0.0494 0.0274 1.562 1.12 1.01 1.23 0.0446 0.0499 0.371 0.4304 1.05 0.948 1.15 PRS_PLINK_1e.04 272.11 Hypercholesterolemia Both 1253 13101 3 endocrine/metabolic brown 13101, 1253 3276, 300 3275, 322 3275, 311 3275, 320 0.0353 0.0299 0.238 0.6231 1.04 0.977 1.1 0.0812 0.0851 0.34 0.4686 1.08 0.918 1.28 0.0324 0.0856 0.705 0.1516 1.03 0.873 1.22 0.0746 0.0852 0.381 0.4186 1.08 0.912 1.27 PRS_PLINK_1e.04 272.12 Hyperglyceridemia Both 299 6615 3 endocrine/metabolic brown 6615, 299 1654, 72 1654, 91 1653, 83 1654, 53 -0.0818 0.058 0.158 0.8006 0.921 0.823 1.03 0.239 0.16 0.135 0.8702 1.27 0.928 1.74 0.146 0.164 0.372 0.43 1.16 0.84 1.59 -0.275 0.182 0.13 0.8844 0.76 0.532 1.08 PRS_PLINK_1e.04 272.13 Mixed hyperlipidemia Both 613 10611 3 endocrine/metabolic brown 10611, 613 2653, 129 2653, 166 2652, 169 2653, 149 0.0439 0.042 0.295 0.5296 1.04 0.962 1.13 0.271 0.122 0.0261 1.584 1.31 1.03 1.66 0.259 0.121 0.0321 1.493 1.3 1.02 1.64 0.153 0.125 0.22 0.6568 1.17 0.912 1.49 PRS_PLINK_1e.04 272.9 Unspecified disorder of lipoid metabolism Both 83 1580 3 endocrine/metabolic brown 1580, 83 395, 21 395, 20 395, 23 395, 19 -0.0403 0.11 0.714 0.1464 0.96 0.774 1.19 -0.0767 0.309 0.804 0.09479 0.926 0.506 1.7 0.0427 0.304 0.888 0.05142 1.04 0.575 1.89 -0.0964 0.315 0.759 0.1195 0.908 0.49 1.68 PRS_PLINK_1e.04 274 Gout and other crystal arthropathies Both 419 8694 3 endocrine/metabolic brown 8694, 419 2174, 110 2173, 96 2173, 110 2174, 103 -0.0145 0.0494 0.77 0.1137 0.986 0.895 1.09 -0.124 0.142 0.381 0.4186 0.883 0.669 1.17 0.0105 0.137 0.939 0.02727 1.01 0.772 1.32 -0.0655 0.139 0.638 0.1949 0.937 0.713 1.23 PRS_PLINK_1e.04 274.1 Gout Both 380 8351 3 endocrine/metabolic brown 8351, 380 2088, 96 2088, 92 2087, 100 2088, 92 -0.0169 0.0518 0.744 0.1287 0.983 0.888 1.09 -0.0291 0.148 0.844 0.07379 0.971 0.727 1.3 0.0466 0.145 0.748 0.1263 1.05 0.789 1.39 -0.0435 0.148 0.769 0.1143 0.957 0.716 1.28 PRS_PLINK_1e.04 274.11 Gouty arthropathy Both 174 3935 3 endocrine/metabolic brown 3935, 174 984, 45 984, 39 983, 43 984, 47 0.0365 0.0743 0.623 0.2054 1.04 0.897 1.2 -0.107 0.218 0.626 0.2036 0.899 0.586 1.38 -0.0452 0.214 0.833 0.07958 0.956 0.628 1.45 0.0431 0.211 0.838 0.07676 1.04 0.691 1.58 PRS_PLINK_1e.04 274.2 Crystal arthropathies Both 47 616 3 endocrine/metabolic brown 616, 47 154, 14 154, 8 154, 11 154, 14 0.0643 0.146 0.66 0.1807 1.07 0.801 1.42 -0.513 0.431 0.234 0.6308 0.599 0.257 1.39 -0.21 0.394 0.594 0.2261 0.811 0.374 1.76 0.00344 0.393 0.993 0.003047 1 0.465 2.17 PRS_PLINK_1e.04 274.21 Chondrocalcinosis Both 43 557 3 endocrine/metabolic brown 557, 43 140, 14 139, 7 139, 11 139, 11 -0.0347 0.153 0.821 0.08575 0.966 0.715 1.3 -0.596 0.452 0.187 0.7289 0.551 0.227 1.33 -0.229 0.402 0.569 0.2446 0.796 0.362 1.75 -0.257 0.42 0.541 0.2672 0.773 0.34 1.76 PRS_PLINK_1e.04 275 Disorders of mineral metabolism Both 1135 17928 3 endocrine/metabolic brown 17928, 1135 4482, 274 4482, 292 4482, 302 4482, 267 -0.00845 0.0306 0.782 0.1066 0.992 0.934 1.05 0.0655 0.0864 0.449 0.3481 1.07 0.901 1.26 0.0974 0.0859 0.257 0.5907 1.1 0.932 1.3 -0.0346 0.0884 0.696 0.1576 0.966 0.812 1.15 PRS_PLINK_1e.04 275.1 Disorders of iron metabolism Both 66 1029 4 hematopoietic darkorange1 1029, 66 258, 19 257, 11 257, 11 257, 25 0.171 0.128 0.18 0.7446 1.19 0.924 1.52 -0.479 0.37 0.195 0.7108 0.619 0.3 1.28 -0.487 0.367 0.184 0.734 0.615 0.3 1.26 0.269 0.305 0.379 0.4218 1.31 0.719 2.38 PRS_PLINK_1e.04 275.11 Hereditary hemochromatosis Both 28 455 4 hematopoietic darkorange1 455, 28 114, 7 114, 5 113, 7 114, 9 0.271 0.19 0.154 0.8129 1.31 0.903 1.9 -0.338 0.541 0.533 0.2735 0.714 0.247 2.06 0.0257 0.493 0.958 0.01845 1.03 0.39 2.7 0.243 0.471 0.606 0.2174 1.27 0.507 3.21 PRS_PLINK_1e.04 275.2 Disorders of copper metabolism Both 29 353 3 endocrine/metabolic brown 353, 29 89, 4 88, 10 88, 6 88, 9 0.198 0.184 0.281 0.5514 1.22 0.851 1.75 0.878 0.549 0.11 0.9604 2.41 0.821 7.06 0.255 0.606 0.674 0.1711 1.29 0.393 4.23 0.63 0.561 0.261 0.583 1.88 0.626 5.63 PRS_PLINK_1e.04 275.3 Disorders of magnesium metabolism Both 234 5153 3 endocrine/metabolic brown 5153, 234 1289, 59 1288, 60 1288, 56 1288, 59 -0.0714 0.0664 0.282 0.5493 0.931 0.817 1.06 0.0177 0.185 0.924 0.03439 1.02 0.708 1.46 -0.0895 0.188 0.634 0.1982 0.914 0.633 1.32 -0.026 0.186 0.889 0.05115 0.974 0.677 1.4 PRS_PLINK_1e.04 275.5 Disorders of calcium/phosphorus metabolism Both 901 14914 3 endocrine/metabolic brown 14914, 901 3729, 217 3728, 239 3728, 249 3729, 196 -0.0301 0.0342 0.378 0.4228 0.97 0.907 1.04 0.0978 0.0962 0.309 0.5095 1.1 0.913 1.33 0.141 0.0954 0.139 0.8583 1.15 0.955 1.39 -0.104 0.101 0.304 0.5176 0.902 0.74 1.1 PRS_PLINK_1e.04 275.51 Hypocalcemia Both 296 4361 3 endocrine/metabolic brown 4361, 296 1091, 68 1090, 72 1090, 74 1090, 82 0.0442 0.0605 0.465 0.3321 1.05 0.928 1.18 0.0701 0.172 0.684 0.1649 1.07 0.765 1.5 0.0736 0.171 0.667 0.1756 1.08 0.77 1.51 0.193 0.168 0.25 0.6016 1.21 0.873 1.68 PRS_PLINK_1e.04 275.53 Disorders of phosphorus metabolism Both 283 6260 3 endocrine/metabolic brown 6260, 283 1565, 67 1565, 89 1565, 68 1565, 59 -0.0654 0.06 0.276 0.5595 0.937 0.833 1.05 0.278 0.164 0.0891 1.05 1.32 0.958 1.82 0.0161 0.173 0.926 0.03348 1.02 0.724 1.43 -0.126 0.18 0.483 0.3156 0.882 0.62 1.25 PRS_PLINK_1e.04 275.6 Hypercalcemia Both 326 6160 3 endocrine/metabolic brown 6160, 326 1540, 82 1540, 83 1540, 98 1540, 63 -0.0372 0.057 0.513 0.2895 0.963 0.862 1.08 0.019 0.158 0.905 0.04358 1.02 0.748 1.39 0.196 0.153 0.198 0.7039 1.22 0.903 1.64 -0.256 0.169 0.131 0.8835 0.774 0.556 1.08 PRS_PLINK_1e.04 276 Disorders of fluid, electrolyte, and acid-base balance Both 2452 20596 3 endocrine/metabolic brown 20596, 2452 5149, 602 5149, 587 5149, 648 5149, 614 0.0012 0.0214 0.955 0.01989 1 0.96 1.04 -0.02 0.0615 0.746 0.1275 0.98 0.869 1.11 0.0743 0.0601 0.217 0.664 1.08 0.957 1.21 0.0186 0.0608 0.759 0.1195 1.02 0.904 1.15 PRS_PLINK_1e.04 276.1 Electrolyte imbalance Both 1289 18188 3 endocrine/metabolic brown 18188, 1289 4547, 302 4547, 304 4547, 354 4547, 328 0.0299 0.0289 0.301 0.5215 1.03 0.974 1.09 0.0105 0.0838 0.9 0.04576 1.01 0.857 1.19 0.164 0.081 0.0426 1.37 1.18 1.01 1.38 0.0851 0.0824 0.302 0.5206 1.09 0.926 1.28 PRS_PLINK_1e.04 276.11 Hyperosmolality and/or hypernatremia Both 82 2291 3 endocrine/metabolic brown 2291, 82 573, 19 573, 22 572, 24 573, 17 -0.00449 0.109 0.967 0.01453 0.996 0.804 1.23 0.159 0.304 0.602 0.2204 1.17 0.646 2.13 0.234 0.3 0.434 0.3626 1.26 0.703 2.27 -0.134 0.321 0.675 0.1705 0.874 0.466 1.64 PRS_PLINK_1e.04 276.12 Hyposmolality and/or hyponatremia Both 457 10290 3 endocrine/metabolic brown 10290, 457 2573, 109 2572, 110 2572, 123 2573, 115 0.0566 0.0478 0.236 0.6266 1.06 0.964 1.16 0.00878 0.137 0.949 0.02283 1.01 0.772 1.32 0.126 0.133 0.345 0.4618 1.13 0.873 1.47 0.059 0.135 0.663 0.1782 1.06 0.813 1.38 PRS_PLINK_1e.04 276.13 Hyperpotassemia Both 480 11464 3 endocrine/metabolic brown 11464, 480 2866, 106 2866, 108 2866, 124 2866, 142 0.112 0.0469 0.0171 1.767 1.12 1.02 1.23 0.0178 0.138 0.897 0.04714 1.02 0.777 1.33 0.173 0.134 0.195 0.7089 1.19 0.915 1.55 0.304 0.13 0.0197 1.707 1.36 1.05 1.75 PRS_PLINK_1e.04 276.14 Hypopotassemia Both 426 10040 3 endocrine/metabolic brown 10040, 426 2510, 101 2510, 95 2510, 120 2510, 109 -0.0235 0.0495 0.635 0.1975 0.977 0.887 1.08 -0.0651 0.144 0.652 0.1858 0.937 0.706 1.24 0.175 0.137 0.201 0.6962 1.19 0.911 1.56 0.0705 0.14 0.615 0.2111 1.07 0.815 1.41 PRS_PLINK_1e.04 276.4 Acid-base balance disorder Both 360 9462 3 endocrine/metabolic brown 9462, 360 2366, 97 2365, 91 2365, 83 2366, 89 -0.034 0.0533 0.523 0.2812 0.967 0.871 1.07 -0.0679 0.147 0.644 0.1909 0.934 0.7 1.25 -0.156 0.151 0.302 0.5206 0.856 0.637 1.15 -0.0825 0.148 0.577 0.2385 0.921 0.689 1.23 PRS_PLINK_1e.04 276.41 Acidosis Both 292 8206 3 endocrine/metabolic brown 8206, 292 2052, 79 2051, 76 2051, 65 2052, 72 -0.044 0.0588 0.454 0.3427 0.957 0.853 1.07 -0.0402 0.162 0.804 0.09501 0.961 0.7 1.32 -0.195 0.168 0.247 0.6077 0.823 0.592 1.14 -0.0934 0.164 0.568 0.2456 0.911 0.661 1.26 PRS_PLINK_1e.04 276.42 Alkalosis Both 88 2156 3 endocrine/metabolic brown 2156, 88 539, 26 539, 23 539, 21 539, 18 -0.179 0.108 0.099 1.004 0.836 0.676 1.03 -0.124 0.282 0.659 0.1812 0.883 0.509 1.53 -0.203 0.288 0.481 0.3179 0.816 0.464 1.44 -0.381 0.299 0.203 0.6932 0.683 0.381 1.23 PRS_PLINK_1e.04 276.5 Hypovolemia Both 1420 18562 3 endocrine/metabolic brown 18562, 1420 4641, 350 4640, 345 4640, 380 4641, 345 -0.0175 0.0276 0.525 0.2799 0.983 0.931 1.04 -0.00237 0.0786 0.976 0.01055 0.998 0.855 1.16 0.0855 0.0768 0.266 0.5757 1.09 0.937 1.27 -0.00922 0.0786 0.907 0.04255 0.991 0.849 1.16 PRS_PLINK_1e.04 276.6 Fluid overload Both 141 5514 3 endocrine/metabolic brown 5514, 141 1379, 41 1378, 37 1378, 30 1379, 33 -0.0583 0.0827 0.481 0.3182 0.943 0.802 1.11 -0.112 0.224 0.619 0.2086 0.894 0.576 1.39 -0.31 0.236 0.19 0.7212 0.734 0.462 1.17 -0.256 0.231 0.268 0.5719 0.774 0.492 1.22 PRS_PLINK_1e.04 276.8 Polydipsia Both 59 726 3 endocrine/metabolic brown 726, 59 182, 16 181, 12 181, 17 182, 14 -0.0805 0.132 0.541 0.267 0.923 0.713 1.19 -0.282 0.379 0.457 0.3398 0.754 0.359 1.59 0.123 0.353 0.728 0.1377 1.13 0.566 2.26 -0.0656 0.362 0.856 0.06752 0.936 0.461 1.9 PRS_PLINK_1e.04 277 Other disorders of metabolism Both 1305 17554 3 endocrine/metabolic brown 17554, 1305 4388, 323 4388, 350 4388, 316 4389, 316 -0.0169 0.0288 0.557 0.2544 0.983 0.929 1.04 0.0845 0.0801 0.292 0.5351 1.09 0.93 1.27 -0.0267 0.0819 0.745 0.128 0.974 0.829 1.14 -0.0159 0.0819 0.846 0.0725 0.984 0.838 1.16 PRS_PLINK_1e.04 277.2 Other disorders of purine and pyrimidine metabolism Both 54 1499 3 endocrine/metabolic brown 1499, 54 375, 13 375, 12 374, 15 375, 14 0.101 0.141 0.473 0.325 1.11 0.84 1.46 -0.0293 0.381 0.939 0.0275 0.971 0.46 2.05 0.107 0.371 0.774 0.1114 1.11 0.538 2.3 0.169 0.368 0.646 0.19 1.18 0.575 2.44 PRS_PLINK_1e.04 277.4 Disorders of bilirubin excretion Both 274 3368 3 endocrine/metabolic brown 3368, 274 842, 67 842, 61 842, 62 842, 84 0.0413 0.0639 0.518 0.2858 1.04 0.919 1.18 -0.0692 0.182 0.704 0.1525 0.933 0.653 1.33 -0.0768 0.181 0.671 0.1734 0.926 0.65 1.32 0.229 0.169 0.176 0.7539 1.26 0.902 1.75 PRS_PLINK_1e.04 277.5 Other disorders of lipoid metabolism Both 297 4429 3 endocrine/metabolic brown 4429, 297 1108, 70 1107, 78 1107, 61 1107, 88 0.0267 0.0595 0.653 0.1849 1.03 0.914 1.15 0.116 0.168 0.492 0.308 1.12 0.807 1.56 -0.115 0.178 0.518 0.2857 0.891 0.628 1.26 0.236 0.165 0.152 0.8181 1.27 0.917 1.75 PRS_PLINK_1e.04 277.51 Lipoprotein disorders Both 242 3610 3 endocrine/metabolic brown 3610, 242 903, 60 902, 60 902, 49 903, 73 0.0147 0.0653 0.822 0.08527 1.01 0.893 1.15 0.00891 0.186 0.962 0.01693 1.01 0.701 1.45 -0.18 0.195 0.358 0.4465 0.836 0.57 1.23 0.207 0.179 0.248 0.6053 1.23 0.866 1.75 PRS_PLINK_1e.04 277.7 Dysmetabolic syndrome X Both 176 4065 3 endocrine/metabolic brown 4065, 176 1017, 44 1016, 48 1016, 40 1016, 44 -0.00723 0.0769 0.925 0.03381 0.993 0.854 1.15 0.103 0.209 0.621 0.2066 1.11 0.736 1.67 -0.113 0.217 0.604 0.2187 0.893 0.583 1.37 0.000767 0.214 0.997 0.001242 1 0.658 1.52 PRS_PLINK_1e.04 278 Overweight, obesity and other hyperalimentation Both 6929 16514 3 endocrine/metabolic brown 16514, 6929 4129, 1749 4128, 1774 4128, 1740 4129, 1665 -0.0238 0.0144 0.0989 1.005 0.976 0.949 1 0.0147 0.0406 0.717 0.1444 1.01 0.937 1.1 -0.0118 0.0407 0.772 0.1126 0.988 0.913 1.07 -0.0591 0.041 0.149 0.8256 0.943 0.87 1.02 PRS_PLINK_1e.04 278.1 Obesity Both 5730 16504 3 endocrine/metabolic brown 16504, 5730 4126, 1447 4126, 1454 4126, 1457 4126, 1372 -0.0185 0.0154 0.23 0.6382 0.982 0.952 1.01 0.00695 0.0435 0.873 0.05899 1.01 0.925 1.1 0.00126 0.0434 0.977 0.01018 1 0.92 1.09 -0.0619 0.0439 0.158 0.8003 0.94 0.863 1.02 PRS_PLINK_1e.04 278.11 Morbid obesity Both 2350 16388 3 endocrine/metabolic brown 16388, 2350 4097, 587 4097, 580 4097, 595 4097, 588 0.00393 0.0222 0.86 0.06558 1 0.961 1.05 -0.00884 0.0631 0.889 0.0513 0.991 0.876 1.12 -0.00599 0.0628 0.924 0.03428 0.994 0.879 1.12 -0.011 0.0628 0.861 0.06511 0.989 0.874 1.12 PRS_PLINK_1e.04 278.3 Localized adiposity Both 109 1993 3 endocrine/metabolic brown 1993, 109 499, 26 498, 34 498, 19 498, 30 -0.0091 0.0943 0.923 0.03474 0.991 0.824 1.19 0.274 0.261 0.292 0.5339 1.32 0.789 2.19 -0.318 0.299 0.287 0.5421 0.728 0.405 1.31 0.17 0.271 0.53 0.2755 1.19 0.697 2.01 PRS_PLINK_1e.04 278.4 Abnormal weight gain Both 944 11140 3 endocrine/metabolic brown 11140, 944 2785, 238 2785, 245 2785, 223 2785, 237 -0.00414 0.034 0.903 0.04433 0.996 0.932 1.06 0.0282 0.0949 0.767 0.1154 1.03 0.854 1.24 -0.0737 0.097 0.447 0.3494 0.929 0.768 1.12 -0.00847 0.0956 0.929 0.03181 0.992 0.822 1.2 PRS_PLINK_1e.04 279 Disorders involving the immune mechanism Both 951 14675 3 endocrine/metabolic brown 14675, 951 3668, 221 3669, 257 3668, 250 3669, 223 0.00416 0.0335 0.901 0.04519 1 0.94 1.07 0.154 0.0945 0.104 0.9828 1.17 0.969 1.4 0.124 0.095 0.191 0.7183 1.13 0.94 1.36 0.00634 0.0975 0.948 0.02313 1.01 0.831 1.22 PRS_PLINK_1e.04 279.1 Immunity deficiency Both 331 5824 3 endocrine/metabolic brown 5824, 331 1456, 81 1456, 100 1456, 82 1456, 68 -0.0718 0.056 0.2 0.6994 0.931 0.834 1.04 0.211 0.153 0.166 0.7789 1.24 0.916 1.67 -0.00545 0.16 0.973 0.012 0.995 0.727 1.36 -0.194 0.167 0.246 0.6089 0.824 0.594 1.14 PRS_PLINK_1e.04 279.11 Deficiency of humoral immunity Both 107 1527 3 endocrine/metabolic brown 1527, 107 382, 23 382, 29 381, 30 382, 25 0.00966 0.0992 0.922 0.03506 1.01 0.831 1.23 0.218 0.279 0.435 0.3614 1.24 0.72 2.15 0.249 0.279 0.372 0.4295 1.28 0.743 2.22 0.0652 0.292 0.823 0.08435 1.07 0.602 1.89 PRS_PLINK_1e.04 279.2 Autoimmune disease NEC Both 288 3917 3 endocrine/metabolic brown 3917, 288 979, 70 979, 72 979, 81 979, 65 -0.0276 0.0615 0.654 0.1847 0.973 0.862 1.1 0.0296 0.172 0.864 0.06368 1.03 0.735 1.44 0.153 0.168 0.362 0.4413 1.17 0.839 1.62 -0.0895 0.176 0.611 0.2137 0.914 0.647 1.29 PRS_PLINK_1e.04 279.7 Other immunological findings Both 1629 18435 3 endocrine/metabolic brown 18435, 1629 4608, 399 4609, 411 4608, 400 4609, 419 0.0292 0.0261 0.262 0.5818 1.03 0.978 1.08 0.0317 0.0733 0.665 0.1769 1.03 0.894 1.19 0.00373 0.0739 0.96 0.01785 1 0.868 1.16 0.0577 0.0731 0.43 0.3665 1.06 0.918 1.22 PRS_PLINK_1e.04 279.8 Other specified disorders involving the immune mechanism Both 241 3237 3 endocrine/metabolic brown 3237, 241 809, 55 809, 64 809, 71 809, 51 -0.01 0.066 0.879 0.05588 0.99 0.87 1.13 0.135 0.188 0.474 0.3245 1.14 0.791 1.65 0.258 0.184 0.161 0.7927 1.29 0.902 1.86 -0.11 0.198 0.578 0.2379 0.896 0.608 1.32 PRS_PLINK_1e.04 280 Iron deficiency anemias Both 1411 16515 4 hematopoietic darkorange1 16515, 1411 4128, 330 4129, 375 4128, 373 4129, 333 0.00047 0.0278 0.987 0.005889 1 0.947 1.06 0.13 0.0786 0.0993 1.003 1.14 0.976 1.33 0.125 0.0789 0.112 0.9489 1.13 0.971 1.32 0.0154 0.0811 0.85 0.07062 1.02 0.866 1.19 PRS_PLINK_1e.04 280.1 Iron deficiency anemias, unspecified or not due to blood loss Both 1369 16380 4 hematopoietic darkorange1 16380, 1369 4094, 320 4095, 365 4095, 358 4095, 326 0.00236 0.0282 0.933 0.02997 1 0.948 1.06 0.132 0.0797 0.0966 1.015 1.14 0.976 1.33 0.116 0.0802 0.148 0.8309 1.12 0.96 1.31 0.0254 0.0821 0.758 0.1206 1.03 0.873 1.2 PRS_PLINK_1e.04 280.2 Iron deficiency anemia secondary to blood loss (chronic) Both 516 8499 4 hematopoietic darkorange1 8499, 516 2125, 120 2125, 134 2124, 144 2125, 118 -0.000939 0.0455 0.984 0.007209 0.999 0.914 1.09 0.111 0.129 0.387 0.4122 1.12 0.869 1.44 0.2 0.127 0.115 0.9381 1.22 0.952 1.57 -0.00131 0.133 0.992 0.003443 0.999 0.77 1.3 PRS_PLINK_1e.04 281 Other deficiency anemia Both 132 2362 4 hematopoietic darkorange1 2362, 132 591, 34 590, 27 590, 37 591, 34 0.0996 0.0905 0.271 0.5673 1.1 0.925 1.32 -0.21 0.257 0.415 0.3818 0.811 0.49 1.34 0.0958 0.24 0.69 0.1614 1.1 0.688 1.76 0.0239 0.245 0.923 0.03503 1.02 0.633 1.66 PRS_PLINK_1e.04 281.1 Megaloblastic anemia Both 74 1190 4 hematopoietic darkorange1 1190, 74 298, 21 297, 16 297, 20 298, 17 0.0904 0.122 0.458 0.3387 1.09 0.862 1.39 -0.301 0.333 0.367 0.4358 0.74 0.385 1.42 -0.0632 0.315 0.841 0.07523 0.939 0.506 1.74 -0.147 0.326 0.651 0.1867 0.863 0.456 1.63 PRS_PLINK_1e.04 281.11 Pernicious anemia Both 30 528 4 hematopoietic darkorange1 528, 30 132, 9 132, 9 132, 7 132, 5 -0.0162 0.176 0.927 0.03297 0.984 0.696 1.39 0.0305 0.463 0.947 0.02343 1.03 0.416 2.56 -0.278 0.479 0.561 0.2507 0.757 0.296 1.93 -0.484 0.512 0.344 0.4633 0.616 0.226 1.68 PRS_PLINK_1e.04 281.12 Other vitamin B12 deficiency anemia Both 60 875 4 hematopoietic darkorange1 875, 60 219, 14 219, 14 218, 17 219, 15 0.206 0.136 0.13 0.8854 1.23 0.941 1.61 -0.0232 0.377 0.951 0.02181 0.977 0.467 2.05 0.303 0.368 0.41 0.3873 1.35 0.659 2.78 0.205 0.373 0.583 0.2344 1.23 0.591 2.55 PRS_PLINK_1e.04 281.9 Deficiency anemias Both 62 1259 4 hematopoietic darkorange1 1259, 62 315, 15 315, 12 314, 17 315, 18 0.0905 0.13 0.486 0.3133 1.09 0.849 1.41 -0.211 0.369 0.567 0.2462 0.81 0.393 1.67 0.174 0.348 0.618 0.209 1.19 0.601 2.35 0.117 0.344 0.734 0.1343 1.12 0.573 2.21 PRS_PLINK_1e.04 282 Hereditary hemolytic anemias Both 107 1535 4 hematopoietic darkorange1 1535, 107 384, 27 384, 21 383, 21 384, 38 0.132 0.0991 0.183 0.7376 1.14 0.94 1.39 -0.254 0.295 0.388 0.411 0.775 0.435 1.38 -0.232 0.29 0.424 0.3722 0.793 0.449 1.4 0.387 0.259 0.135 0.8711 1.47 0.887 2.45 PRS_PLINK_1e.04 282.8 Other hemoglobinopathies Both 72 996 4 hematopoietic darkorange1 996, 72 249, 21 249, 13 249, 15 249, 23 -0.0194 0.117 0.868 0.06155 0.981 0.78 1.23 -0.533 0.361 0.139 0.8556 0.587 0.289 1.19 -0.345 0.338 0.307 0.5135 0.708 0.365 1.37 -0.0127 0.31 0.967 0.01447 0.987 0.538 1.81 PRS_PLINK_1e.04 282.9 Other hereditary hemolytic anemias Both 54 875 4 hematopoietic darkorange1 875, 54 219, 14 219, 10 218, 10 219, 20 0.206 0.139 0.139 0.8563 1.23 0.935 1.61 -0.304 0.403 0.451 0.3458 0.738 0.335 1.63 -0.316 0.397 0.426 0.3706 0.729 0.335 1.59 0.487 0.351 0.166 0.7798 1.63 0.817 3.24 PRS_PLINK_1e.04 283 Acquired hemolytic anemias Both 33 721 4 hematopoietic darkorange1 721, 33 181, 7 180, 8 180, 10 180, 8 0.095 0.175 0.586 0.2318 1.1 0.781 1.55 0.0347 0.493 0.944 0.02508 1.04 0.394 2.72 0.366 0.466 0.432 0.3641 1.44 0.578 3.6 0.188 0.474 0.691 0.1607 1.21 0.477 3.05 PRS_PLINK_1e.04 283.1 Autoimmune hemolytic anemias Both 15 285 4 hematopoietic darkorange1 285, 15 72, 3 71, 3 71, 4 71, 5 0.386 0.258 0.135 0.8692 1.47 0.887 2.44 -0.0708 0.722 0.922 0.03535 0.932 0.227 3.83 0.0884 0.667 0.895 0.04837 1.09 0.296 4.04 0.515 0.662 0.437 0.3596 1.67 0.457 6.12 PRS_PLINK_1e.04 284 Aplastic anemia Both 183 3261 4 hematopoietic darkorange1 3261, 183 816, 48 815, 43 815, 54 815, 38 -0.0681 0.0732 0.352 0.4538 0.934 0.809 1.08 -0.0836 0.212 0.694 0.1586 0.92 0.607 1.39 0.162 0.202 0.424 0.373 1.18 0.791 1.75 -0.18 0.219 0.411 0.3864 0.835 0.544 1.28 PRS_PLINK_1e.04 284.1 Pancytopenia Both 162 2862 4 hematopoietic darkorange1 2862, 162 716, 44 715, 38 715, 48 716, 32 -0.111 0.078 0.153 0.8142 0.895 0.768 1.04 -0.0966 0.224 0.666 0.1763 0.908 0.585 1.41 0.146 0.213 0.493 0.3073 1.16 0.763 1.75 -0.266 0.234 0.255 0.5931 0.766 0.484 1.21 PRS_PLINK_1e.04 285 Other anemias Both 4075 18678 4 hematopoietic darkorange1 18678, 4075 4669, 1019 4669, 1041 4669, 1004 4670, 1011 -0.0113 0.0176 0.519 0.2847 0.989 0.955 1.02 0.0168 0.0494 0.733 0.1349 1.02 0.923 1.12 -0.0267 0.0498 0.592 0.2275 0.974 0.883 1.07 -0.0244 0.0498 0.624 0.2047 0.976 0.885 1.08 PRS_PLINK_1e.04 285.1 Acute posthemorrhagic anemia Both 878 13898 4 hematopoietic darkorange1 13898, 878 3475, 234 3474, 224 3474, 217 3475, 203 -0.0407 0.0345 0.237 0.6251 0.96 0.897 1.03 -0.0464 0.0961 0.629 0.2015 0.955 0.791 1.15 -0.0766 0.0969 0.429 0.3675 0.926 0.766 1.12 -0.146 0.0985 0.139 0.8557 0.865 0.713 1.05 PRS_PLINK_1e.04 285.2 Anemia of chronic disease Both 399 9311 4 hematopoietic darkorange1 9311, 399 2328, 108 2328, 89 2327, 100 2328, 102 -0.0557 0.0501 0.266 0.5744 0.946 0.857 1.04 -0.185 0.145 0.202 0.6954 0.831 0.626 1.1 -0.062 0.141 0.66 0.1807 0.94 0.713 1.24 -0.0491 0.14 0.726 0.1388 0.952 0.723 1.25 PRS_PLINK_1e.04 285.21 Anemia in chronic kidney disease Both 25 4014 4 hematopoietic darkorange1 4014, 25 1004, 9 1003, 6 1003, 5 1004, 5 -0.203 0.174 0.241 0.6171 0.816 0.581 1.15 -0.356 0.46 0.439 0.3572 0.701 0.285 1.73 -0.543 0.48 0.258 0.588 0.581 0.227 1.49 -0.575 0.481 0.232 0.6344 0.563 0.219 1.44 PRS_PLINK_1e.04 285.22 Anemia in neoplastic disease Both 251 3351 4 hematopoietic darkorange1 3351, 251 838, 65 838, 54 837, 70 838, 62 -0.075 0.0641 0.242 0.6158 0.928 0.818 1.05 -0.178 0.188 0.344 0.4631 0.837 0.579 1.21 0.1 0.178 0.573 0.2419 1.11 0.78 1.57 -0.0256 0.183 0.889 0.05115 0.975 0.681 1.4 PRS_PLINK_1e.04 286 Coagulation defects Both 1153 16667 4 hematopoietic darkorange1 16667, 1153 4167, 298 4167, 286 4166, 297 4167, 272 -0.028 0.0302 0.354 0.4512 0.972 0.916 1.03 -0.0415 0.0854 0.627 0.2029 0.959 0.811 1.13 -0.00344 0.0847 0.968 0.01429 0.997 0.844 1.18 -0.0956 0.0864 0.269 0.5705 0.909 0.767 1.08 PRS_PLINK_1e.04 286.1 Congenital coagulation defects Both 105 1388 4 hematopoietic darkorange1 1388, 105 347, 29 347, 29 347, 27 347, 20 -0.0576 0.0982 0.557 0.2538 0.944 0.779 1.14 0.0117 0.268 0.965 0.01542 1.01 0.599 1.71 -0.0864 0.273 0.751 0.1242 0.917 0.538 1.57 -0.368 0.291 0.206 0.6866 0.692 0.391 1.22 PRS_PLINK_1e.04 286.11 Von willebrand's disease Both 38 454 4 hematopoietic darkorange1 454, 38 114, 11 113, 12 113, 10 114, 5 -0.144 0.168 0.392 0.4066 0.866 0.623 1.2 0.00377 0.428 0.993 0.003063 1 0.433 2.32 -0.223 0.446 0.617 0.2097 0.8 0.334 1.92 -0.795 0.511 0.12 0.9214 0.452 0.166 1.23 PRS_PLINK_1e.04 286.12 Congenital deficiency of other clotting factors (including factor VII) Both 50 720 4 hematopoietic darkorange1 720, 50 180, 12 180, 13 180, 12 180, 13 0.0371 0.147 0.801 0.09642 1.04 0.778 1.38 0.106 0.389 0.785 0.105 1.11 0.519 2.38 -0.0324 0.404 0.936 0.02871 0.968 0.439 2.14 0.0749 0.395 0.85 0.07073 1.08 0.497 2.34 PRS_PLINK_1e.04 286.2 Encounter for long-term (current) use of anticoagulants Both 684 11376 4 hematopoietic darkorange1 11376, 684 2844, 155 2844, 174 2844, 186 2844, 169 0.0468 0.0396 0.237 0.6248 1.05 0.97 1.13 0.115 0.113 0.307 0.5127 1.12 0.9 1.4 0.186 0.111 0.0953 1.021 1.2 0.968 1.5 0.0875 0.114 0.442 0.355 1.09 0.873 1.36 PRS_PLINK_1e.04 286.3 Coagulation defects complicating pregnancy or postpartum Female 67 812 4 hematopoietic darkorange1 812, 67 202, 16 203, 20 203, 18 203, 13 -0.0927 0.121 0.442 0.3541 0.911 0.719 1.15 0.171 0.348 0.622 0.206 1.19 0.6 2.35 0.0897 0.344 0.794 0.09993 1.09 0.557 2.15 -0.169 0.371 0.649 0.1878 0.845 0.408 1.75 PRS_PLINK_1e.04 286.4 Acquired coagulation factor deficiency Both 49 1101 4 hematopoietic darkorange1 1101, 49 276, 15 275, 12 275, 11 275, 11 -0.051 0.145 0.725 0.1394 0.95 0.715 1.26 -0.194 0.371 0.6 0.2216 0.823 0.398 1.7 -0.3 0.385 0.435 0.3612 0.741 0.348 1.57 -0.362 0.381 0.342 0.4656 0.696 0.33 1.47 PRS_PLINK_1e.04 286.5 Hemorrhagic disorder due to intrinsic circulating anticoagulants Both 26 552 4 hematopoietic darkorange1 552, 26 138, 9 138, 5 138, 5 138, 7 0.00573 0.181 0.975 0.0111 1.01 0.705 1.43 -0.502 0.506 0.321 0.4939 0.605 0.225 1.63 -0.557 0.519 0.283 0.548 0.573 0.207 1.58 -0.199 0.47 0.672 0.1729 0.819 0.326 2.06 PRS_PLINK_1e.04 286.6 Defibrination syndrome Both 820 12168 4 hematopoietic darkorange1 12168, 820 3042, 192 3042, 203 3042, 218 3042, 207 0.0312 0.0362 0.389 0.4099 1.03 0.961 1.11 0.0537 0.104 0.604 0.2191 1.06 0.861 1.29 0.122 0.102 0.229 0.6395 1.13 0.926 1.38 0.066 0.103 0.522 0.2825 1.07 0.873 1.31 PRS_PLINK_1e.04 286.7 Other and unspecified coagulation defects Both 942 14209 4 hematopoietic darkorange1 14209, 942 3552, 228 3552, 236 3552, 238 3552, 240 0.0141 0.0337 0.676 0.1702 1.01 0.949 1.08 0.0357 0.0956 0.709 0.1494 1.04 0.859 1.25 0.0402 0.0954 0.673 0.1718 1.04 0.863 1.26 0.0449 0.0952 0.637 0.1959 1.05 0.868 1.26 PRS_PLINK_1e.04 286.8 Hypercoagulable state Both 331 4523 4 hematopoietic darkorange1 4523, 331 1131, 85 1131, 80 1130, 84 1131, 82 -0.0287 0.0562 0.609 0.2151 0.972 0.87 1.08 -0.0507 0.16 0.751 0.1245 0.951 0.695 1.3 -0.00919 0.158 0.954 0.02062 0.991 0.727 1.35 -0.0417 0.159 0.793 0.101 0.959 0.703 1.31 PRS_PLINK_1e.04 286.81 Primary hypercoagulable state Both 316 4319 4 hematopoietic darkorange1 4319, 316 1080, 81 1080, 75 1079, 81 1080, 79 -0.0199 0.0573 0.728 0.1379 0.98 0.876 1.1 -0.0666 0.164 0.685 0.1644 0.936 0.678 1.29 0.0117 0.161 0.942 0.02581 1.01 0.738 1.39 -0.0236 0.162 0.884 0.05349 0.977 0.711 1.34 PRS_PLINK_1e.04 286.9 Abnormal coagulation profile Both 237 4724 4 hematopoietic darkorange1 4724, 237 1181, 67 1181, 61 1181, 63 1181, 46 -0.131 0.0641 0.0405 1.392 0.877 0.773 0.994 -0.0724 0.179 0.687 0.1632 0.93 0.654 1.32 -0.0645 0.178 0.717 0.1447 0.938 0.662 1.33 -0.361 0.193 0.0609 1.215 0.697 0.478 1.02 PRS_PLINK_1e.04 287 Purpura and other hemorrhagic conditions Both 930 13349 4 hematopoietic darkorange1 13349, 930 3338, 237 3337, 222 3337, 256 3337, 215 -0.0311 0.0335 0.353 0.4517 0.969 0.908 1.04 -0.0659 0.0962 0.494 0.3065 0.936 0.775 1.13 0.0832 0.0932 0.372 0.4299 1.09 0.905 1.3 -0.086 0.0971 0.376 0.4253 0.918 0.759 1.11 PRS_PLINK_1e.04 287.1 Spontaneous ecchymoses Both 56 977 4 hematopoietic darkorange1 977, 56 245, 12 244, 13 244, 19 244, 12 -0.0249 0.135 0.854 0.06871 0.975 0.749 1.27 -0.0527 0.393 0.893 0.04901 0.949 0.44 2.05 0.453 0.365 0.215 0.6681 1.57 0.769 3.21 0.0434 0.391 0.912 0.04022 1.04 0.486 2.25 PRS_PLINK_1e.04 287.3 Thrombocytopenia Both 825 12146 4 hematopoietic darkorange1 12146, 825 3037, 207 3036, 188 3036, 237 3037, 193 -0.0205 0.0357 0.565 0.2481 0.98 0.914 1.05 -0.0949 0.104 0.36 0.4441 0.909 0.742 1.11 0.142 0.0983 0.149 0.8271 1.15 0.95 1.4 -0.0585 0.103 0.57 0.2439 0.943 0.771 1.15 PRS_PLINK_1e.04 287.31 Primary thrombocytopenia Both 198 2763 4 hematopoietic darkorange1 2763, 198 691, 48 691, 44 690, 59 691, 47 0.0275 0.0725 0.705 0.1518 1.03 0.892 1.18 -0.0779 0.211 0.713 0.1471 0.925 0.611 1.4 0.218 0.199 0.274 0.5626 1.24 0.841 1.84 0.0206 0.209 0.922 0.03544 1.02 0.678 1.54 PRS_PLINK_1e.04 287.32 Secondary thrombocytopenia Both 171 2570 4 hematopoietic darkorange1 2570, 171 643, 31 642, 42 642, 55 643, 43 0.0907 0.0791 0.251 0.5997 1.09 0.938 1.28 0.31 0.237 0.19 0.7206 1.36 0.857 2.17 0.579 0.226 0.0105 1.98 1.78 1.15 2.78 0.342 0.236 0.147 0.8337 1.41 0.887 2.24 PRS_PLINK_1e.04 287.4 Qualitative platelet defects Both 39 550 4 hematopoietic darkorange1 550, 39 138, 9 137, 13 137, 7 138, 10 -0.0262 0.156 0.866 0.0623 0.974 0.718 1.32 0.409 0.431 0.342 0.4659 1.51 0.647 3.5 -0.218 0.468 0.64 0.1936 0.804 0.321 2.01 0.0971 0.449 0.829 0.08159 1.1 0.457 2.65 PRS_PLINK_1e.04 288 Diseases of white blood cells Both 1584 19077 4 hematopoietic darkorange1 19077, 1584 4769, 375 4769, 425 4769, 417 4769, 367 -0.0346 0.0261 0.185 0.732 0.966 0.918 1.02 0.127 0.0738 0.086 1.065 1.14 0.982 1.31 0.107 0.074 0.149 0.8266 1.11 0.962 1.29 -0.0219 0.0762 0.774 0.1115 0.978 0.843 1.14 PRS_PLINK_1e.04 288.1 Decreased white blood cell count Both 635 7833 4 hematopoietic darkorange1 7833, 635 1959, 153 1958, 177 1958, 166 1958, 139 -0.0651 0.0411 0.113 0.9468 0.937 0.865 1.02 0.154 0.115 0.18 0.744 1.17 0.931 1.46 0.0847 0.116 0.465 0.3327 1.09 0.867 1.37 -0.0916 0.121 0.449 0.3481 0.912 0.72 1.16 PRS_PLINK_1e.04 288.11 Neutropenia Both 426 5342 4 hematopoietic darkorange1 5342, 426 1336, 102 1335, 118 1335, 118 1336, 88 -0.0655 0.0504 0.193 0.7137 0.937 0.848 1.03 0.163 0.14 0.243 0.6143 1.18 0.895 1.55 0.148 0.14 0.29 0.537 1.16 0.881 1.52 -0.154 0.15 0.303 0.5182 0.857 0.639 1.15 PRS_PLINK_1e.04 288.2 Elevated white blood cell count Both 1241 17853 4 hematopoietic darkorange1 17853, 1241 4463, 294 4463, 328 4463, 328 4463, 291 -0.0226 0.0293 0.44 0.3561 0.978 0.923 1.04 0.108 0.0829 0.191 0.7195 1.11 0.947 1.31 0.111 0.0829 0.179 0.7483 1.12 0.95 1.32 -0.00644 0.0852 0.94 0.027 0.994 0.841 1.17 PRS_PLINK_1e.04 288.3 Eosinophilia Both 88 966 4 hematopoietic darkorange1 966, 88 242, 21 241, 27 241, 23 242, 17 -0.0731 0.108 0.499 0.3016 0.93 0.752 1.15 0.169 0.298 0.571 0.2433 1.18 0.66 2.13 0.118 0.309 0.703 0.1533 1.13 0.614 2.06 -0.227 0.326 0.486 0.3137 0.797 0.421 1.51 PRS_PLINK_1e.04 289 Other diseases of blood and blood-forming organs Both 615 8459 4 hematopoietic darkorange1 8459, 615 2114, 153 2115, 167 2114, 151 2115, 144 -0.0218 0.0419 0.604 0.2192 0.978 0.901 1.06 0.0896 0.116 0.439 0.3575 1.09 0.872 1.37 -0.0175 0.118 0.882 0.05444 0.983 0.779 1.24 -0.0491 0.12 0.682 0.1662 0.952 0.753 1.2 PRS_PLINK_1e.04 289.3 Personal history of diseases of blood and blood-forming organs Both 382 4803 4 hematopoietic darkorange1 4803, 382 1200, 91 1201, 103 1200, 94 1201, 94 0.00974 0.0541 0.857 0.067 1.01 0.908 1.12 0.116 0.149 0.436 0.3604 1.12 0.839 1.5 0.0291 0.151 0.848 0.07183 1.03 0.765 1.38 0.0401 0.152 0.792 0.1015 1.04 0.773 1.4 PRS_PLINK_1e.04 289.4 Lymphadenitis Both 1682 17910 4 hematopoietic darkorange1 17910, 1682 4477, 421 4477, 423 4477, 416 4478, 422 -0.0152 0.0253 0.549 0.2604 0.985 0.937 1.04 0.00463 0.072 0.949 0.02283 1 0.872 1.16 -0.00967 0.0723 0.894 0.04887 0.99 0.86 1.14 0.00705 0.072 0.922 0.03526 1.01 0.874 1.16 PRS_PLINK_1e.04 289.5 Diseases of spleen Both 122 1824 4 hematopoietic darkorange1 1824, 122 456, 27 456, 27 456, 37 456, 31 -0.0339 0.0903 0.707 0.1503 0.967 0.81 1.15 -0.0364 0.274 0.894 0.04858 0.964 0.564 1.65 0.268 0.256 0.295 0.5307 1.31 0.792 2.16 0.132 0.263 0.616 0.2103 1.14 0.681 1.91 PRS_PLINK_1e.04 289.8 Polycythemia, secondary Both 58 1121 4 hematopoietic darkorange1 1121, 58 281, 15 280, 17 280, 8 280, 18 -0.017 0.13 0.896 0.04773 0.983 0.762 1.27 0.146 0.346 0.673 0.1723 1.16 0.587 2.28 -0.601 0.416 0.148 0.8301 0.548 0.243 1.24 0.299 0.346 0.388 0.4113 1.35 0.684 2.66 PRS_PLINK_1e.04 289.9 Abnormality of red blood cells Both 104 1661 4 hematopoietic darkorange1 1661, 104 415, 29 415, 27 415, 24 415, 24 -0.0694 0.0981 0.479 0.3193 0.933 0.77 1.13 -0.0795 0.271 0.769 0.1138 0.924 0.543 1.57 -0.184 0.276 0.506 0.2957 0.832 0.484 1.43 -0.177 0.276 0.521 0.2834 0.838 0.488 1.44 PRS_PLINK_1e.04 290 Delirium dementia and amnestic and other cognitive disorders Both 220 3976 5 mental disorders magenta 3976, 220 994, 47 994, 67 994, 52 994, 54 0.0342 0.069 0.621 0.2072 1.03 0.904 1.18 0.355 0.192 0.0647 1.189 1.43 0.979 2.08 0.104 0.203 0.609 0.2152 1.11 0.745 1.65 0.137 0.201 0.494 0.306 1.15 0.774 1.7 PRS_PLINK_1e.04 290.1 Dementias Both 102 1425 5 mental disorders magenta 1425, 102 357, 26 356, 33 356, 20 356, 23 -0.0315 0.101 0.755 0.1221 0.969 0.795 1.18 0.254 0.265 0.338 0.4707 1.29 0.767 2.17 -0.217 0.296 0.463 0.3347 0.805 0.451 1.44 -0.123 0.286 0.667 0.176 0.884 0.505 1.55 PRS_PLINK_1e.04 290.11 Alzheimer's disease Both 32 374 5 mental disorders magenta 374, 32 94, 10 93, 11 93, 8 94, 3 -0.214 0.192 0.266 0.5755 0.808 0.554 1.18 0.192 0.457 0.675 0.1709 1.21 0.494 2.97 -0.0926 0.484 0.848 0.07144 0.912 0.353 2.36 -1.12 0.597 0.0601 1.221 0.325 0.101 1.05 PRS_PLINK_1e.04 290.12 Dementia with cerebral degenerations Both 19 254 5 mental disorders magenta 254, 19 64, 6 63, 5 63, 3 64, 5 -0.103 0.215 0.632 0.1991 0.902 0.592 1.38 -0.169 0.578 0.77 0.1133 0.845 0.272 2.62 -0.704 0.661 0.287 0.5426 0.494 0.135 1.81 0.0315 0.586 0.957 0.01899 1.03 0.327 3.26 PRS_PLINK_1e.04 290.13 Senile dementia Both 56 808 5 mental disorders magenta 808, 56 202, 14 202, 18 202, 12 202, 12 0.00162 0.139 0.991 0.004074 1 0.763 1.31 0.231 0.353 0.514 0.2892 1.26 0.63 2.52 -0.178 0.381 0.641 0.1931 0.837 0.397 1.77 -0.203 0.38 0.594 0.226 0.817 0.388 1.72 PRS_PLINK_1e.04 290.16 Vascular dementia Both 8 230 5 mental disorders magenta 230, 8 58, 2 57, 4 57, 0 58, 2 0.11 0.299 0.712 0.1475 1.12 0.621 2.01 1.22 0.909 0.18 0.7455 3.39 0.57 20.1 -0.436 1.1 0.693 0.1595 0.646 0.0742 5.63 0.179 0.779 0.818 0.08728 1.2 0.26 5.51 PRS_PLINK_1e.04 290.2 Delirium due to conditions classified elsewhere Both 112 2648 5 mental disorders magenta 2648, 112 662, 22 662, 38 662, 24 662, 28 0.0609 0.0956 0.524 0.2803 1.06 0.881 1.28 0.548 0.264 0.0375 1.426 1.73 1.03 2.9 0.0996 0.288 0.729 0.1372 1.1 0.629 1.94 0.248 0.28 0.376 0.4245 1.28 0.74 2.22 PRS_PLINK_1e.04 290.3 Other persistent mental disorders due to conditions classified elsewhere Both 266 3563 5 mental disorders magenta 3563, 266 891, 61 891, 73 890, 67 891, 65 0.0479 0.0635 0.45 0.3466 1.05 0.926 1.19 0.191 0.177 0.282 0.5501 1.21 0.855 1.71 0.0886 0.181 0.624 0.2047 1.09 0.767 1.56 0.0776 0.183 0.671 0.1735 1.08 0.756 1.55 PRS_PLINK_1e.04 291 Other specified nonpsychotic and/or transient mental disorders Both 883 12406 5 mental disorders magenta 12406, 883 3101, 223 3101, 235 3101, 199 3102, 226 0.000159 0.035 0.996 0.001576 1 0.934 1.07 0.0493 0.0967 0.61 0.2144 1.05 0.869 1.27 -0.109 0.101 0.278 0.5552 0.897 0.736 1.09 0.0185 0.0976 0.85 0.07077 1.02 0.841 1.23 PRS_PLINK_1e.04 291.1 Transient mental disorders due to conditions classified elsewhere Both 111 1244 5 mental disorders magenta 1244, 111 311, 32 311, 30 311, 22 311, 27 -0.114 0.0959 0.234 0.6299 0.892 0.739 1.08 -0.126 0.263 0.632 0.1994 0.881 0.526 1.48 -0.375 0.279 0.18 0.7451 0.687 0.398 1.19 -0.172 0.267 0.519 0.2845 0.842 0.499 1.42 PRS_PLINK_1e.04 291.4 Specific nonpsychotic mental disorders due to brain damage Both 198 2462 5 mental disorders magenta 2462, 198 616, 48 615, 53 615, 46 616, 51 0.0291 0.0746 0.696 0.1574 1.03 0.89 1.19 0.129 0.204 0.529 0.2764 1.14 0.762 1.7 0.000737 0.211 0.997 0.001212 1 0.662 1.51 0.0745 0.205 0.716 0.145 1.08 0.721 1.61 PRS_PLINK_1e.04 291.8 Alteration of consciousness Both 619 9415 5 mental disorders magenta 9415, 619 2353, 153 2354, 166 2353, 144 2354, 156 0.0154 0.0421 0.714 0.1465 1.02 0.935 1.1 0.0787 0.115 0.495 0.3056 1.08 0.863 1.36 -0.049 0.119 0.681 0.1668 0.952 0.754 1.2 0.0212 0.117 0.857 0.06726 1.02 0.812 1.28 PRS_PLINK_1e.04 292 Neurological disorders Both 1853 20094 5 mental disorders magenta 20094, 1853 5023, 449 5023, 483 5023, 494 5024, 427 -0.0111 0.0243 0.647 0.1891 0.989 0.943 1.04 0.0771 0.0686 0.261 0.5832 1.08 0.944 1.24 0.0957 0.0682 0.161 0.7938 1.1 0.963 1.26 -0.0497 0.0705 0.481 0.318 0.952 0.829 1.09 PRS_PLINK_1e.04 292.1 Aphasia/speech disturbance Both 692 8862 5 mental disorders magenta 8862, 692 2216, 151 2215, 173 2215, 218 2216, 150 0.0411 0.0396 0.299 0.5238 1.04 0.964 1.13 0.133 0.115 0.246 0.6096 1.14 0.912 1.43 0.374 0.11 0.000635 3.197 1.45 1.17 1.8 -0.00362 0.119 0.976 0.01069 0.996 0.79 1.26 PRS_PLINK_1e.04 292.11 Aphasia Both 214 2930 5 mental disorders magenta 2930, 214 733, 46 732, 59 732, 67 733, 42 0.0239 0.0706 0.735 0.1336 1.02 0.892 1.18 0.253 0.2 0.206 0.6862 1.29 0.87 1.91 0.393 0.196 0.0448 1.349 1.48 1.01 2.17 -0.0747 0.217 0.73 0.1367 0.928 0.607 1.42 PRS_PLINK_1e.04 292.12 Symbolic dysfunction Both 80 948 5 mental disorders magenta 948, 80 237, 17 237, 23 237, 25 237, 15 0.00512 0.112 0.964 0.01615 1.01 0.807 1.25 0.303 0.321 0.345 0.4616 1.35 0.722 2.54 0.363 0.317 0.252 0.5982 1.44 0.772 2.68 -0.179 0.349 0.607 0.2165 0.836 0.422 1.66 PRS_PLINK_1e.04 292.2 Mild cognitive impairment Both 74 1255 5 mental disorders magenta 1255, 74 314, 19 314, 20 313, 18 314, 17 0.0811 0.119 0.497 0.3038 1.08 0.858 1.37 0.0408 0.316 0.897 0.0471 1.04 0.561 1.93 -0.0229 0.324 0.944 0.02516 0.977 0.518 1.84 -0.0192 0.328 0.953 0.0207 0.981 0.516 1.87 PRS_PLINK_1e.04 292.3 Memory loss Both 615 7825 5 mental disorders magenta 7825, 615 1957, 162 1956, 152 1956, 156 1956, 145 -0.0309 0.0414 0.455 0.3423 0.97 0.894 1.05 -0.0593 0.117 0.612 0.2134 0.942 0.749 1.19 -0.0383 0.116 0.742 0.1297 0.962 0.766 1.21 -0.105 0.118 0.375 0.4259 0.901 0.714 1.14 PRS_PLINK_1e.04 292.4 Altered mental status Both 505 9637 5 mental disorders magenta 9637, 505 2410, 112 2409, 130 2409, 125 2409, 138 0.0708 0.0455 0.12 0.9213 1.07 0.982 1.17 0.154 0.131 0.24 0.6201 1.17 0.902 1.51 0.106 0.132 0.421 0.3761 1.11 0.858 1.44 0.221 0.13 0.0877 1.057 1.25 0.968 1.61 PRS_PLINK_1e.04 292.5 Transient alteration of awareness Both 124 2011 5 mental disorders magenta 2011, 124 503, 30 503, 35 502, 28 503, 31 0.0164 0.093 0.86 0.06553 1.02 0.847 1.22 0.152 0.251 0.544 0.2642 1.16 0.712 1.9 -0.0425 0.263 0.872 0.05962 0.958 0.572 1.61 0.0878 0.259 0.734 0.134 1.09 0.657 1.81 PRS_PLINK_1e.04 292.6 Hallucinations Both 56 985 5 mental disorders magenta 985, 56 247, 15 246, 20 246, 10 246, 11 -0.161 0.136 0.235 0.6282 0.851 0.653 1.11 0.369 0.339 0.276 0.5598 1.45 0.745 2.81 -0.509 0.393 0.195 0.709 0.601 0.278 1.3 -0.271 0.385 0.481 0.3178 0.762 0.359 1.62 PRS_PLINK_1e.04 293 Symptoms involving head and neck Both 181 2041 5 mental disorders magenta 2041, 181 511, 48 510, 44 510, 44 510, 45 -0.00978 0.0769 0.899 0.04632 0.99 0.852 1.15 -0.0964 0.216 0.655 0.184 0.908 0.595 1.39 -0.0494 0.215 0.818 0.08723 0.952 0.625 1.45 -0.0426 0.215 0.843 0.07425 0.958 0.629 1.46 PRS_PLINK_1e.04 293.1 Swelling, mass, or lump in head and neck [Space-occupying lesion, intracranial NOS] Both 1922 18780 5 mental disorders magenta 18780, 1922 4695, 481 4695, 480 4695, 525 4695, 436 -0.0208 0.0239 0.385 0.4149 0.979 0.935 1.03 0.000838 0.0677 0.99 0.004308 1 0.876 1.14 0.0888 0.0663 0.181 0.7431 1.09 0.96 1.24 -0.0948 0.0692 0.171 0.7678 0.91 0.794 1.04 PRS_PLINK_1e.04 295 Schizophrenia and other psychotic disorders Both 260 3827 5 mental disorders magenta 3827, 260 957, 62 957, 80 956, 63 957, 55 0.00101 0.0647 0.988 0.005426 1 0.882 1.14 0.277 0.178 0.12 0.9214 1.32 0.931 1.87 0.0372 0.187 0.842 0.07474 1.04 0.72 1.5 -0.114 0.191 0.551 0.2592 0.892 0.614 1.3 PRS_PLINK_1e.04 295.1 Schizophrenia Both 62 792 5 mental disorders magenta 792, 62 198, 17 198, 21 198, 13 198, 11 -0.0646 0.129 0.616 0.2105 0.937 0.728 1.21 0.16 0.339 0.637 0.1955 1.17 0.604 2.28 -0.291 0.378 0.441 0.3552 0.747 0.356 1.57 -0.442 0.392 0.26 0.5853 0.643 0.298 1.39 PRS_PLINK_1e.04 295.2 Paranoid disorders Both 37 494 5 mental disorders magenta 494, 37 124, 10 123, 12 123, 11 124, 4 -0.165 0.163 0.31 0.508 0.848 0.616 1.17 0.393 0.443 0.376 0.425 1.48 0.621 3.53 -0.102 0.469 0.829 0.08166 0.903 0.36 2.27 -1 0.556 0.0723 1.141 0.368 0.124 1.09 PRS_PLINK_1e.04 295.3 Psychosis Both 192 3040 5 mental disorders magenta 3040, 192 760, 43 760, 59 760, 48 760, 42 0.0167 0.0747 0.823 0.08457 1.02 0.878 1.18 0.362 0.211 0.0866 1.062 1.44 0.949 2.17 0.143 0.216 0.508 0.2941 1.15 0.755 1.76 -0.0103 0.221 0.963 0.01636 0.99 0.642 1.53 PRS_PLINK_1e.04 296 Mood disorders Both 7035 11598 5 mental disorders magenta 11598, 7035 2900, 1734 2899, 1770 2899, 1832 2900, 1698 -0.0102 0.0156 0.512 0.291 0.99 0.96 1.02 0.0141 0.0444 0.751 0.1245 1.01 0.93 1.11 0.0396 0.044 0.369 0.4334 1.04 0.954 1.13 -0.033 0.0445 0.459 0.3383 0.968 0.887 1.06 PRS_PLINK_1e.04 296.1 Bipolar Both 661 7146 5 mental disorders magenta 7146, 661 1787, 174 1786, 170 1786, 160 1787, 157 -0.0305 0.0408 0.455 0.3424 0.97 0.895 1.05 -0.0598 0.115 0.603 0.2193 0.942 0.752 1.18 -0.096 0.116 0.408 0.3891 0.909 0.724 1.14 -0.109 0.116 0.346 0.4609 0.897 0.714 1.13 PRS_PLINK_1e.04 296.2 Depression Both 6761 11593 5 mental disorders magenta 11593, 6761 2899, 1670 2898, 1704 2898, 1759 2898, 1627 -0.0119 0.0158 0.451 0.346 0.988 0.958 1.02 0.0155 0.0449 0.73 0.1366 1.02 0.93 1.11 0.0366 0.0446 0.412 0.3849 1.04 0.95 1.13 -0.0373 0.0452 0.409 0.3884 0.963 0.882 1.05 PRS_PLINK_1e.04 296.22 Major depressive disorder Both 6323 11594 5 mental disorders magenta 11594, 6323 2899, 1547 2898, 1602 2898, 1662 2899, 1512 -0.00883 0.0162 0.586 0.2322 0.991 0.96 1.02 0.0323 0.046 0.483 0.3163 1.03 0.944 1.13 0.0554 0.0456 0.225 0.6479 1.06 0.967 1.16 -0.0359 0.0463 0.438 0.358 0.965 0.881 1.06 PRS_PLINK_1e.04 297 Suicidal ideation or attempt Both 484 5874 5 mental disorders magenta 5874, 484 1469, 130 1468, 121 1468, 103 1469, 130 -0.0259 0.0483 0.592 0.2275 0.974 0.886 1.07 -0.0251 0.135 0.853 0.06928 0.975 0.748 1.27 -0.217 0.141 0.125 0.9025 0.805 0.611 1.06 0.000788 0.134 0.995 0.002043 1 0.77 1.3 PRS_PLINK_1e.04 297.1 Suicidal ideation Both 386 4749 5 mental disorders magenta 4749, 386 1188, 106 1187, 88 1187, 82 1187, 110 -0.0236 0.0545 0.664 0.1775 0.977 0.878 1.09 -0.144 0.153 0.347 0.4592 0.866 0.642 1.17 -0.252 0.157 0.109 0.9633 0.777 0.571 1.06 0.0195 0.147 0.894 0.04858 1.02 0.765 1.36 PRS_PLINK_1e.04 297.2 Suicide or self-inflicted injury Both 157 1843 5 mental disorders magenta 1843, 157 461, 45 461, 41 460, 32 461, 39 -0.0469 0.0834 0.574 0.241 0.954 0.81 1.12 -0.12 0.23 0.602 0.2206 0.887 0.565 1.39 -0.364 0.241 0.131 0.8824 0.695 0.433 1.11 -0.119 0.232 0.608 0.2164 0.887 0.563 1.4 PRS_PLINK_1e.04 300 Anxiety disorders Both 7346 11590 5 mental disorders magenta 11590, 7346 2898, 1770 2897, 1847 2897, 1950 2898, 1778 -0.00362 0.0155 0.815 0.0889 0.996 0.967 1.03 0.038 0.044 0.388 0.4109 1.04 0.953 1.13 0.0881 0.0436 0.0432 1.365 1.09 1 1.19 -0.0024 0.0442 0.957 0.01923 0.998 0.915 1.09 PRS_PLINK_1e.04 300.1 Anxiety disorder Both 6937 11594 5 mental disorders magenta 11594, 6937 2899, 1674 2898, 1732 2898, 1849 2899, 1681 -0.00352 0.0157 0.823 0.08458 0.996 0.966 1.03 0.0276 0.0449 0.539 0.2684 1.03 0.941 1.12 0.0889 0.0444 0.0452 1.345 1.09 1 1.19 -0.00142 0.045 0.975 0.01111 0.999 0.914 1.09 PRS_PLINK_1e.04 300.11 Generalized anxiety disorder Both 2551 11311 5 mental disorders magenta 11311, 2551 2828, 627 2828, 619 2827, 680 2828, 624 -0.00441 0.0228 0.847 0.07236 0.996 0.952 1.04 -0.00704 0.0656 0.914 0.03882 0.993 0.873 1.13 0.0757 0.0643 0.239 0.621 1.08 0.951 1.22 -0.00763 0.0653 0.907 0.04241 0.992 0.873 1.13 PRS_PLINK_1e.04 300.12 Agorophobia, social phobia, and panic disorder Both 666 7109 5 mental disorders magenta 7109, 666 1778, 170 1777, 177 1777, 163 1777, 156 0.00577 0.0433 0.894 0.04864 1.01 0.924 1.09 0.0989 0.121 0.415 0.3821 1.1 0.87 1.4 -0.0167 0.125 0.893 0.04899 0.983 0.77 1.26 -0.0467 0.124 0.706 0.1512 0.954 0.749 1.22 PRS_PLINK_1e.04 300.13 Phobia Both 483 5486 5 mental disorders magenta 5486, 483 1372, 127 1371, 115 1371, 131 1372, 109 -0.0406 0.0495 0.412 0.3848 0.96 0.871 1.06 -0.0964 0.143 0.499 0.3019 0.908 0.687 1.2 0.0785 0.137 0.568 0.2459 1.08 0.826 1.42 -0.0979 0.142 0.489 0.3103 0.907 0.687 1.2 PRS_PLINK_1e.04 300.3 Obsessive-compulsive disorders Both 186 1993 5 mental disorders magenta 1993, 186 499, 47 498, 54 498, 41 498, 44 -0.0485 0.0781 0.535 0.272 0.953 0.818 1.11 0.0923 0.214 0.667 0.1762 1.1 0.721 1.67 -0.111 0.227 0.625 0.2041 0.895 0.574 1.4 -0.137 0.222 0.538 0.269 0.872 0.564 1.35 PRS_PLINK_1e.04 300.4 Dysthymic disorder Both 1079 9276 5 mental disorders magenta 9276, 1079 2319, 261 2319, 264 2319, 264 2319, 290 0.00926 0.0324 0.775 0.1105 1.01 0.947 1.08 0.0343 0.094 0.715 0.1456 1.03 0.861 1.24 0.0123 0.0942 0.896 0.04746 1.01 0.842 1.22 0.104 0.0921 0.257 0.5898 1.11 0.927 1.33 PRS_PLINK_1e.04 300.8 Acute reaction to stress Both 209 2844 5 mental disorders magenta 2844, 209 711, 48 711, 55 711, 55 711, 50 -0.0287 0.0711 0.686 0.1636 0.972 0.845 1.12 0.192 0.205 0.349 0.4567 1.21 0.811 1.81 0.196 0.204 0.336 0.4736 1.22 0.816 1.81 0.046 0.206 0.823 0.08437 1.05 0.699 1.57 PRS_PLINK_1e.04 300.9 Posttraumatic stress disorder Both 425 5147 5 mental disorders magenta 5147, 425 1287, 104 1287, 106 1286, 115 1287, 100 -0.00394 0.0514 0.939 0.02735 0.996 0.901 1.1 0.0441 0.147 0.764 0.117 1.05 0.784 1.39 0.138 0.145 0.341 0.4671 1.15 0.864 1.53 -0.0286 0.149 0.848 0.07176 0.972 0.726 1.3 PRS_PLINK_1e.04 301 Personality disorders Both 256 3037 5 mental disorders magenta 3037, 256 760, 57 759, 65 759, 67 759, 67 0.0146 0.0655 0.824 0.08433 1.01 0.893 1.15 0.136 0.192 0.478 0.3202 1.15 0.786 1.67 0.203 0.19 0.285 0.5448 1.22 0.844 1.78 0.201 0.189 0.288 0.5399 1.22 0.844 1.77 PRS_PLINK_1e.04 301.2 Antisocial/borderline personality disorder Both 142 1680 5 mental disorders magenta 1680, 142 420, 39 420, 29 420, 37 420, 37 -0.0526 0.0882 0.551 0.2592 0.949 0.798 1.13 -0.329 0.26 0.206 0.6864 0.72 0.433 1.2 -0.0417 0.243 0.864 0.06368 0.959 0.596 1.54 -0.0794 0.243 0.744 0.1286 0.924 0.574 1.49 PRS_PLINK_1e.04 302 Sexual and gender identity disorders Both 1274 7229 5 mental disorders magenta 7229, 1274 1808, 296 1807, 316 1807, 345 1807, 316 0.0223 0.0306 0.466 0.3317 1.02 0.963 1.09 0.0697 0.0891 0.434 0.3625 1.07 0.9 1.28 0.17 0.0877 0.0529 1.276 1.19 0.998 1.41 0.0784 0.0889 0.377 0.4233 1.08 0.909 1.29 PRS_PLINK_1e.04 302.1 Decreased libido Both 202 2304 5 mental disorders magenta 2304, 202 576, 48 576, 57 576, 49 576, 48 -0.0101 0.0735 0.891 0.05012 0.99 0.857 1.14 0.173 0.203 0.394 0.4044 1.19 0.798 1.77 0.0144 0.212 0.946 0.02419 1.01 0.67 1.54 -0.0322 0.211 0.879 0.0562 0.968 0.641 1.46 PRS_PLINK_1e.04 303 Psychogenic and somatoform disorders Both 2721 10830 5 mental disorders magenta 10830, 2721 2708, 666 2707, 641 2707, 732 2708, 682 0.0112 0.0217 0.606 0.2174 1.01 0.969 1.06 -0.0376 0.0631 0.551 0.259 0.963 0.851 1.09 0.0909 0.0615 0.139 0.8562 1.1 0.971 1.24 0.00895 0.0621 0.885 0.05289 1.01 0.893 1.14 PRS_PLINK_1e.04 303.1 Dissociative disorder Both 58 973 5 mental disorders magenta 973, 58 244, 19 243, 10 243, 22 243, 7 -0.174 0.13 0.183 0.7372 0.841 0.651 1.09 -0.523 0.394 0.185 0.7338 0.593 0.274 1.28 0.0993 0.32 0.756 0.1213 1.1 0.59 2.07 -0.907 0.433 0.036 1.443 0.404 0.173 0.943 PRS_PLINK_1e.04 303.3 Psychogenic disorder Both 2582 10695 5 mental disorders magenta 10695, 2582 2674, 640 2674, 614 2673, 685 2674, 643 0.00521 0.0221 0.814 0.08942 1.01 0.963 1.05 -0.0391 0.0642 0.543 0.2654 0.962 0.848 1.09 0.0683 0.0628 0.277 0.5578 1.07 0.947 1.21 -0.00281 0.0634 0.965 0.01566 0.997 0.881 1.13 PRS_PLINK_1e.04 303.31 Gastrointestinal malfunction arising from mental factors Both 232 2566 5 mental disorders magenta 2566, 232 642, 51 641, 69 641, 58 642, 54 -0.0122 0.0678 0.857 0.06701 0.988 0.865 1.13 0.263 0.192 0.17 0.7697 1.3 0.893 1.89 0.135 0.197 0.495 0.3057 1.14 0.777 1.68 0.0198 0.203 0.922 0.03529 1.02 0.686 1.52 PRS_PLINK_1e.04 303.4 Somatoform disorder Both 600 6828 5 mental disorders magenta 6828, 600 1707, 138 1707, 156 1707, 152 1707, 154 0.0386 0.0427 0.366 0.437 1.04 0.956 1.13 0.118 0.122 0.333 0.4776 1.13 0.886 1.43 0.103 0.123 0.402 0.3962 1.11 0.872 1.41 0.0994 0.122 0.416 0.3808 1.1 0.869 1.4 PRS_PLINK_1e.04 304 Adjustment reaction Both 1639 11237 5 mental disorders magenta 11237, 1639 2810, 395 2809, 413 2809, 409 2809, 422 0.00651 0.0265 0.806 0.09393 1.01 0.956 1.06 0.0562 0.0762 0.461 0.3366 1.06 0.911 1.23 0.0308 0.0765 0.687 0.1629 1.03 0.888 1.2 0.0568 0.0758 0.454 0.3429 1.06 0.912 1.23 PRS_PLINK_1e.04 305.2 Eating disorder Both 374 5278 5 mental disorders magenta 5278, 374 1320, 80 1319, 95 1319, 103 1320, 96 0.0466 0.0532 0.381 0.4186 1.05 0.944 1.16 0.188 0.157 0.231 0.6355 1.21 0.887 1.64 0.268 0.155 0.0838 1.077 1.31 0.965 1.77 0.168 0.157 0.284 0.5471 1.18 0.87 1.61 PRS_PLINK_1e.04 306 Other mental disorder Both 927 8284 5 mental disorders magenta 8284, 927 2071, 230 2071, 231 2071, 240 2071, 226 -0.000247 0.0348 0.994 0.002461 1 0.934 1.07 0.0315 0.0995 0.752 0.1239 1.03 0.849 1.25 0.0531 0.0988 0.591 0.2284 1.05 0.869 1.28 -0.00076 0.0996 0.994 0.00265 0.999 0.822 1.21 PRS_PLINK_1e.04 306.1 Mental disorders durring/after pregnancy Female 444 2938 5 mental disorders magenta 2938, 444 735, 122 734, 108 734, 99 735, 115 -0.0164 0.0515 0.75 0.125 0.984 0.889 1.09 -0.0912 0.148 0.538 0.2695 0.913 0.683 1.22 -0.178 0.15 0.237 0.6259 0.837 0.624 1.12 -0.00219 0.144 0.988 0.005292 0.998 0.752 1.32 PRS_PLINK_1e.04 306.9 Tension headache Both 377 4669 5 mental disorders magenta 4669, 377 1168, 98 1167, 88 1167, 106 1167, 85 -0.0465 0.0525 0.376 0.4248 0.955 0.861 1.06 -0.109 0.152 0.474 0.3243 0.897 0.666 1.21 0.0942 0.146 0.518 0.2856 1.1 0.826 1.46 -0.129 0.153 0.399 0.3992 0.879 0.651 1.19 PRS_PLINK_1e.04 312 Conduct disorders Both 126 1442 5 mental disorders magenta 1442, 126 361, 30 360, 34 360, 31 361, 31 0.0465 0.0935 0.619 0.2084 1.05 0.872 1.26 0.15 0.257 0.56 0.2521 1.16 0.702 1.92 0.0522 0.265 0.844 0.07386 1.05 0.627 1.77 0.0286 0.261 0.913 0.03969 1.03 0.617 1.72 PRS_PLINK_1e.04 312.3 Impulse control disorder Both 45 474 5 mental disorders magenta 474, 45 119, 12 118, 11 118, 6 119, 16 0.15 0.159 0.344 0.4634 1.16 0.851 1.59 0.0154 0.425 0.971 0.01272 1.02 0.442 2.34 -0.57 0.469 0.224 0.6501 0.565 0.226 1.42 0.289 0.387 0.456 0.3413 1.33 0.625 2.85 PRS_PLINK_1e.04 313 Pervasive developmental disorders Both 1038 9717 5 mental disorders magenta 9717, 1038 2430, 289 2429, 242 2429, 266 2429, 240 -0.0508 0.0328 0.121 0.9161 0.95 0.891 1.01 -0.17 0.0916 0.0628 1.202 0.843 0.705 1.01 -0.078 0.0898 0.385 0.4146 0.925 0.776 1.1 -0.177 0.0919 0.0539 1.268 0.838 0.7 1 PRS_PLINK_1e.04 313.1 Attention deficit hyperactivity disorder Both 945 8973 5 mental disorders magenta 8973, 945 2244, 259 2243, 223 2243, 237 2243, 225 -0.0462 0.0344 0.179 0.7461 0.955 0.893 1.02 -0.142 0.096 0.14 0.8544 0.868 0.719 1.05 -0.0826 0.0947 0.383 0.4167 0.921 0.765 1.11 -0.133 0.0958 0.165 0.7823 0.875 0.726 1.06 PRS_PLINK_1e.04 313.2 Tics and stuttering Both 41 478 5 mental disorders magenta 478, 41 120, 12 119, 8 119, 11 120, 10 -0.0398 0.156 0.799 0.09771 0.961 0.708 1.3 -0.283 0.459 0.537 0.2696 0.754 0.307 1.85 -0.184 0.423 0.663 0.1784 0.832 0.363 1.91 -0.247 0.429 0.565 0.2476 0.781 0.337 1.81 PRS_PLINK_1e.04 313.3 Autism Both 46 460 5 mental disorders magenta 460, 46 115, 10 115, 17 115, 10 115, 9 -0.109 0.161 0.499 0.3016 0.897 0.654 1.23 0.524 0.407 0.198 0.704 1.69 0.761 3.75 0.0336 0.445 0.94 0.02696 1.03 0.432 2.47 -0.0673 0.447 0.88 0.0553 0.935 0.389 2.25 PRS_PLINK_1e.04 315 Develomental delays and disorders Both 228 3398 5 mental disorders magenta 3398, 228 850, 56 849, 66 849, 62 850, 44 -0.0761 0.0676 0.261 0.5842 0.927 0.812 1.06 0.193 0.187 0.3 0.5228 1.21 0.842 1.75 0.118 0.188 0.53 0.2761 1.13 0.778 1.63 -0.214 0.204 0.295 0.5308 0.807 0.541 1.2 PRS_PLINK_1e.04 315.1 Learning disorder Both 48 612 5 mental disorders magenta 612, 48 153, 12 153, 13 153, 11 153, 12 -0.151 0.152 0.321 0.4934 0.86 0.638 1.16 0.0302 0.404 0.94 0.02665 1.03 0.467 2.28 -0.15 0.426 0.724 0.1404 0.86 0.373 1.98 -0.213 0.412 0.605 0.218 0.808 0.361 1.81 PRS_PLINK_1e.04 315.2 Speech and language disorder Both 103 1284 5 mental disorders magenta 1284, 103 321, 31 321, 29 321, 22 321, 21 -0.143 0.0997 0.152 0.817 0.867 0.713 1.05 -0.0444 0.266 0.867 0.06184 0.957 0.568 1.61 -0.334 0.283 0.238 0.6234 0.716 0.411 1.25 -0.35 0.286 0.221 0.6566 0.705 0.403 1.23 PRS_PLINK_1e.04 316 Substance addiction and disorders Both 1582 17317 5 mental disorders magenta 17317, 1582 4329, 396 4329, 394 4329, 396 4329, 396 0.000557 0.0265 0.983 0.007354 1 0.95 1.05 0.00452 0.0748 0.952 0.02145 1 0.868 1.16 0.000809 0.0746 0.991 0.003777 1 0.865 1.16 0.0088 0.0748 0.906 0.04271 1.01 0.871 1.17 PRS_PLINK_1e.04 316.1 Polyneuropathy due to drugs Both 283 2989 5 mental disorders magenta 2989, 283 748, 70 747, 64 747, 74 747, 75 0.0281 0.0626 0.653 0.1849 1.03 0.91 1.16 -0.0956 0.179 0.593 0.2271 0.909 0.64 1.29 0.072 0.174 0.679 0.1682 1.07 0.764 1.51 0.0675 0.173 0.697 0.1568 1.07 0.762 1.5 PRS_PLINK_1e.04 317 Alcohol-related disorders Both 975 11667 5 mental disorders magenta 11667, 975 2916, 278 2917, 236 2916, 224 2917, 237 -0.0427 0.0331 0.198 0.7041 0.958 0.898 1.02 -0.144 0.0927 0.119 0.9227 0.866 0.722 1.04 -0.21 0.0938 0.0254 1.594 0.811 0.675 0.975 -0.138 0.0927 0.136 0.8652 0.871 0.726 1.04 PRS_PLINK_1e.04 317.1 Alcoholism Both 736 9664 5 mental disorders magenta 9664, 736 2415, 213 2416, 163 2416, 179 2416, 181 -0.0433 0.038 0.254 0.5954 0.958 0.889 1.03 -0.256 0.108 0.0178 1.749 0.774 0.626 0.957 -0.171 0.106 0.105 0.9773 0.843 0.685 1.04 -0.141 0.105 0.181 0.7423 0.868 0.706 1.07 PRS_PLINK_1e.04 317.11 Alcoholic liver damage Both 90 1791 5 mental disorders magenta 1791, 90 448, 19 448, 23 447, 24 448, 24 0.0853 0.106 0.423 0.3742 1.09 0.884 1.34 0.186 0.304 0.539 0.2681 1.2 0.665 2.18 0.291 0.306 0.341 0.4675 1.34 0.735 2.44 0.211 0.303 0.486 0.3133 1.23 0.682 2.24 PRS_PLINK_1e.04 318 Tobacco use disorder Both 3511 18361 5 mental disorders magenta 18361, 3511 4590, 899 4590, 907 4590, 863 4590, 842 -0.0257 0.0185 0.164 0.7846 0.975 0.94 1.01 0.00697 0.0516 0.892 0.04939 1.01 0.91 1.11 -0.0446 0.0522 0.392 0.4068 0.956 0.863 1.06 -0.072 0.0525 0.17 0.7705 0.93 0.84 1.03 PRS_PLINK_1e.04 320 Meningitis Both 164 1909 6 neurological darkblue 1909, 164 478, 44 477, 40 477, 45 477, 35 -0.0932 0.0791 0.239 0.6221 0.911 0.78 1.06 -0.093 0.224 0.678 0.1686 0.911 0.587 1.41 0.0298 0.22 0.892 0.04942 1.03 0.669 1.59 -0.257 0.232 0.27 0.5694 0.774 0.491 1.22 PRS_PLINK_1e.04 323 Encephalitis Both 66 859 6 neurological darkblue 859, 66 215, 15 215, 16 214, 19 215, 16 0.018 0.122 0.883 0.05404 1.02 0.801 1.29 0.0805 0.359 0.822 0.08488 1.08 0.537 2.19 0.247 0.348 0.479 0.3195 1.28 0.646 2.53 0.0854 0.355 0.81 0.09158 1.09 0.543 2.18 PRS_PLINK_1e.04 323.8 Encephalitis, non-infectious Both 56 726 6 neurological darkblue 726, 56 182, 13 181, 11 181, 18 182, 14 0.0285 0.129 0.826 0.08314 1.03 0.799 1.33 -0.166 0.401 0.68 0.1677 0.847 0.386 1.86 0.334 0.369 0.365 0.4374 1.4 0.678 2.88 0.0333 0.382 0.93 0.0313 1.03 0.489 2.18 PRS_PLINK_1e.04 324 Other CNS infection and poliomyelitis Both 99 1165 6 neurological darkblue 1165, 99 292, 24 291, 30 291, 24 291, 20 -0.157 0.0999 0.117 0.9329 0.855 0.703 1.04 0.234 0.28 0.403 0.3943 1.26 0.73 2.19 0.0255 0.293 0.931 0.03123 1.03 0.577 1.82 -0.164 0.304 0.59 0.2291 0.849 0.468 1.54 PRS_PLINK_1e.04 325 Phlebitis and thrombophlebitis of intracranial venous sinuses Both 22 252 6 neurological darkblue 252, 22 63, 4 63, 5 63, 7 63, 6 -0.0511 0.213 0.81 0.09128 0.95 0.626 1.44 -0.344 0.661 0.603 0.2198 0.709 0.194 2.59 0.255 0.618 0.68 0.1677 1.29 0.384 4.34 0.384 0.59 0.515 0.2883 1.47 0.462 4.67 PRS_PLINK_1e.04 327 Sleep disorders Both 5035 18318 6 neurological darkblue 18318, 5035 4580, 1246 4579, 1256 4579, 1283 4580, 1249 -0.000624 0.016 0.969 0.01369 0.999 0.968 1.03 0.0117 0.0455 0.796 0.09886 1.01 0.926 1.11 0.0272 0.0454 0.549 0.2603 1.03 0.94 1.12 -0.00125 0.0456 0.978 0.009629 0.999 0.913 1.09 PRS_PLINK_1e.04 327.1 Hypersomnia Both 803 10759 6 neurological darkblue 10759, 803 2690, 192 2690, 185 2689, 213 2690, 213 0.0256 0.0367 0.487 0.3128 1.03 0.955 1.1 -0.0359 0.106 0.736 0.1333 0.965 0.783 1.19 0.114 0.103 0.271 0.5666 1.12 0.915 1.37 0.119 0.103 0.249 0.6045 1.13 0.92 1.38 PRS_PLINK_1e.04 327.3 Sleep apnea Both 3107 18035 6 neurological darkblue 18035, 3107 4509, 792 4509, 739 4508, 810 4509, 766 -0.00137 0.0195 0.944 0.02502 0.999 0.961 1.04 -0.0646 0.0558 0.247 0.6065 0.937 0.84 1.05 0.021 0.0549 0.702 0.1536 1.02 0.917 1.14 -0.0384 0.0555 0.489 0.3103 0.962 0.863 1.07 PRS_PLINK_1e.04 327.31 Central/nonobstroctive sleep apnea Both 114 2068 6 neurological darkblue 2068, 114 517, 30 517, 29 517, 24 517, 31 -0.0198 0.0956 0.836 0.078 0.98 0.813 1.18 -0.0239 0.264 0.928 0.03241 0.976 0.581 1.64 -0.227 0.272 0.403 0.395 0.797 0.468 1.36 0.0549 0.256 0.83 0.08073 1.06 0.639 1.75 PRS_PLINK_1e.04 327.32 Obstructive sleep apnea Both 2336 17313 6 neurological darkblue 17313, 2336 4329, 587 4328, 575 4328, 615 4328, 559 -0.00685 0.0221 0.756 0.1212 0.993 0.951 1.04 -0.0195 0.0629 0.756 0.1212 0.981 0.867 1.11 0.0455 0.0621 0.464 0.3336 1.05 0.927 1.18 -0.0538 0.0634 0.396 0.4027 0.948 0.837 1.07 PRS_PLINK_1e.04 327.4 Insomnia Both 2078 17733 6 neurological darkblue 17733, 2078 4434, 495 4433, 548 4433, 508 4433, 526 0.00517 0.0234 0.825 0.0835 1.01 0.96 1.05 0.103 0.0659 0.117 0.9324 1.11 0.975 1.26 0.0136 0.0672 0.84 0.07572 1.01 0.889 1.16 0.0578 0.0665 0.385 0.4148 1.06 0.93 1.21 PRS_PLINK_1e.04 327.41 Organic or persistent insomnia Both 481 6380 6 neurological darkblue 6380, 481 1595, 107 1595, 128 1595, 121 1595, 125 0.0424 0.0478 0.375 0.4262 1.04 0.95 1.15 0.183 0.135 0.175 0.757 1.2 0.922 1.56 0.125 0.137 0.36 0.4437 1.13 0.867 1.48 0.166 0.136 0.222 0.6539 1.18 0.905 1.54 PRS_PLINK_1e.04 327.5 Parasomnia Both 169 2842 6 neurological darkblue 2842, 169 711, 33 710, 50 710, 45 711, 41 0.0294 0.0767 0.701 0.154 1.03 0.886 1.2 0.445 0.225 0.0481 1.318 1.56 1 2.43 0.319 0.23 0.165 0.7837 1.38 0.877 2.16 0.217 0.233 0.352 0.4536 1.24 0.786 1.96 PRS_PLINK_1e.04 327.6 Circadian rhythm sleep disorder Both 121 1530 6 neurological darkblue 1530, 121 383, 29 382, 35 382, 34 383, 23 -0.0374 0.0925 0.686 0.1637 0.963 0.803 1.15 0.163 0.256 0.524 0.2804 1.18 0.713 1.94 0.209 0.26 0.421 0.3755 1.23 0.741 2.05 -0.136 0.282 0.629 0.2011 0.873 0.503 1.52 PRS_PLINK_1e.04 327.7 Sleep related movement disorders Both 579 8755 6 neurological darkblue 8755, 579 2189, 140 2189, 153 2188, 142 2189, 144 -0.0145 0.0426 0.734 0.1344 0.986 0.907 1.07 0.09 0.12 0.454 0.3433 1.09 0.865 1.38 0.0214 0.122 0.861 0.0651 1.02 0.804 1.3 0.0408 0.122 0.738 0.1318 1.04 0.82 1.32 PRS_PLINK_1e.04 327.71 Restless legs syndrome Both 501 7772 6 neurological darkblue 7772, 501 1943, 119 1943, 134 1943, 127 1943, 121 -0.0279 0.0457 0.541 0.2667 0.972 0.889 1.06 0.118 0.129 0.36 0.4436 1.13 0.874 1.45 0.0741 0.131 0.571 0.2435 1.08 0.834 1.39 0.0268 0.132 0.84 0.07584 1.03 0.792 1.33 PRS_PLINK_1e.04 327.72 Sleep related leg cramps Both 32 352 6 neurological darkblue 352, 32 88, 8 88, 7 88, 8 88, 9 0.0214 0.175 0.903 0.04447 1.02 0.725 1.44 -0.194 0.493 0.695 0.1583 0.824 0.313 2.17 0.137 0.498 0.783 0.1061 1.15 0.432 3.04 0.179 0.48 0.709 0.1495 1.2 0.467 3.06 PRS_PLINK_1e.04 331 Other cerebral degenerations Both 200 2884 6 neurological darkblue 2884, 200 721, 45 721, 62 721, 50 721, 43 0.00538 0.0716 0.94 0.02681 1.01 0.874 1.16 0.333 0.2 0.0953 1.021 1.4 0.943 2.06 0.11 0.208 0.597 0.2237 1.12 0.742 1.68 -0.0265 0.215 0.902 0.04485 0.974 0.639 1.49 PRS_PLINK_1e.04 331.1 Hydrocephalus Both 116 1491 6 neurological darkblue 1491, 116 373, 27 373, 35 372, 27 373, 27 0.0221 0.0916 0.81 0.09172 1.02 0.854 1.22 0.25 0.26 0.336 0.474 1.28 0.772 2.14 -0.0106 0.273 0.969 0.01367 0.989 0.579 1.69 -0.0349 0.274 0.899 0.04648 0.966 0.565 1.65 PRS_PLINK_1e.04 331.9 Cerebral degeneration, unspecified Both 82 1345 6 neurological darkblue 1345, 82 337, 19 336, 27 336, 20 336, 16 -0.0238 0.112 0.831 0.08031 0.976 0.785 1.22 0.36 0.298 0.228 0.6422 1.43 0.798 2.57 0.0746 0.316 0.813 0.08978 1.08 0.58 2 -0.0983 0.33 0.766 0.1159 0.906 0.475 1.73 PRS_PLINK_1e.04 332 Parkinson's disease Both 132 1286 6 neurological darkblue 1286, 132 322, 31 321, 34 321, 37 322, 30 -0.0575 0.0886 0.516 0.287 0.944 0.794 1.12 0.0393 0.259 0.879 0.05583 1.04 0.626 1.73 0.172 0.251 0.494 0.3064 1.19 0.726 1.94 -0.0517 0.265 0.845 0.0729 0.95 0.565 1.6 PRS_PLINK_1e.04 333 Extrapyramidal disease and abnormal movement disorders Both 969 12561 6 neurological darkblue 12561, 969 3141, 245 3140, 256 3140, 245 3140, 223 -0.0529 0.0331 0.11 0.9568 0.948 0.889 1.01 0.0491 0.0927 0.596 0.2246 1.05 0.876 1.26 -0.00353 0.0936 0.97 0.01328 0.996 0.83 1.2 -0.0937 0.0958 0.328 0.4844 0.911 0.755 1.1 PRS_PLINK_1e.04 333.1 Essential tremor Both 188 2673 6 neurological darkblue 2673, 188 669, 47 668, 60 668, 41 668, 40 -0.0846 0.0735 0.25 0.6022 0.919 0.796 1.06 0.257 0.2 0.198 0.7042 1.29 0.875 1.91 -0.14 0.217 0.517 0.2862 0.869 0.568 1.33 -0.149 0.218 0.495 0.3055 0.862 0.562 1.32 PRS_PLINK_1e.04 333.2 Myoclonus Both 47 754 6 neurological darkblue 754, 47 189, 12 188, 11 188, 12 189, 12 0.0117 0.144 0.935 0.02916 1.01 0.763 1.34 -0.0554 0.407 0.892 0.04975 0.946 0.426 2.1 -0.0717 0.395 0.856 0.06755 0.931 0.429 2.02 0.0668 0.4 0.867 0.06177 1.07 0.488 2.34 PRS_PLINK_1e.04 333.4 Torsion dystonia Both 148 1684 6 neurological darkblue 1684, 148 421, 38 421, 41 421, 34 421, 35 -0.092 0.0871 0.291 0.536 0.912 0.769 1.08 0.118 0.233 0.612 0.2134 1.13 0.713 1.78 -0.0964 0.241 0.689 0.1615 0.908 0.566 1.46 -0.0998 0.241 0.678 0.1686 0.905 0.565 1.45 PRS_PLINK_1e.04 333.8 Other degenerative diseases of the basal ganglia Both 22 330 6 neurological darkblue 330, 22 83, 4 82, 6 82, 7 83, 5 0.0517 0.204 0.8 0.09691 1.05 0.706 1.57 0.119 0.591 0.841 0.07529 1.13 0.354 3.59 0.386 0.577 0.504 0.298 1.47 0.475 4.55 0.288 0.628 0.646 0.1898 1.33 0.39 4.57 PRS_PLINK_1e.04 334 Degenerative disease of the spinal cord Both 382 4890 6 neurological darkblue 4890, 382 1223, 109 1222, 94 1222, 76 1223, 102 -0.0686 0.0524 0.19 0.7205 0.934 0.843 1.03 -0.153 0.145 0.294 0.5322 0.858 0.645 1.14 -0.36 0.154 0.0191 1.719 0.698 0.516 0.943 -0.0787 0.143 0.582 0.2348 0.924 0.698 1.22 PRS_PLINK_1e.04 334.1 Spinocerebellar disease Both 21 355 6 neurological darkblue 355, 21 89, 9 89, 2 88, 5 89, 5 -0.221 0.203 0.275 0.56 0.802 0.539 1.19 -1.3 0.674 0.0536 1.271 0.272 0.0726 1.02 -0.512 0.519 0.324 0.4893 0.599 0.216 1.66 -0.567 0.537 0.291 0.5362 0.567 0.198 1.63 PRS_PLINK_1e.04 334.2 Anterior horn cell disease Both 38 441 6 neurological darkblue 441, 38 111, 9 110, 13 110, 6 110, 10 0.0741 0.153 0.628 0.2023 1.08 0.798 1.45 0.409 0.44 0.353 0.4519 1.51 0.635 3.57 -0.209 0.504 0.679 0.168 0.812 0.302 2.18 0.437 0.472 0.354 0.4508 1.55 0.614 3.9 PRS_PLINK_1e.04 334.21 Amyotrophic Lateral Sclerosis Both 23 269 6 neurological darkblue 269, 23 68, 4 67, 6 67, 8 67, 5 0.176 0.203 0.386 0.4135 1.19 0.801 1.77 0.359 0.59 0.543 0.2655 1.43 0.451 4.55 0.714 0.594 0.229 0.64 2.04 0.638 6.54 0.667 0.672 0.322 0.4927 1.95 0.521 7.28 PRS_PLINK_1e.04 335 Multiple sclerosis Both 187 2148 6 neurological darkblue 2148, 187 537, 41 537, 56 537, 40 537, 50 0.036 0.0761 0.636 0.1966 1.04 0.893 1.2 0.34 0.211 0.107 0.9706 1.41 0.929 2.13 -0.00348 0.226 0.988 0.005353 0.997 0.639 1.55 0.22 0.217 0.311 0.5078 1.25 0.815 1.9 PRS_PLINK_1e.04 337 Disorders of the autonomic nervous system Both 221 3547 6 neurological darkblue 3547, 221 887, 54 887, 53 886, 56 887, 58 -0.0108 0.068 0.874 0.0585 0.989 0.866 1.13 -0.027 0.196 0.89 0.05046 0.973 0.663 1.43 0.0426 0.193 0.826 0.08313 1.04 0.714 1.52 0.0647 0.192 0.736 0.1332 1.07 0.733 1.55 PRS_PLINK_1e.04 337.1 Peripheral autonomic neuropathy Both 38 1182 6 neurological darkblue 1182, 38 296, 10 295, 7 295, 8 296, 13 0.0139 0.155 0.929 0.03214 1.01 0.748 1.37 -0.307 0.447 0.493 0.3074 0.736 0.306 1.77 -0.209 0.435 0.63 0.2004 0.811 0.346 1.9 0.227 0.395 0.566 0.2469 1.25 0.578 2.72 PRS_PLINK_1e.04 338 Pain Both 9104 14343 6 neurological darkblue 14343, 9104 3586, 2252 3586, 2251 3585, 2347 3586, 2253 0.00168 0.0135 0.901 0.0453 1 0.976 1.03 -0.00466 0.0383 0.903 0.04429 0.995 0.923 1.07 0.0389 0.038 0.306 0.5136 1.04 0.965 1.12 -0.00897 0.0383 0.815 0.08902 0.991 0.919 1.07 PRS_PLINK_1e.04 338.1 Acute pain Both 6977 14252 6 neurological darkblue 14252, 6977 3563, 1756 3563, 1741 3563, 1826 3563, 1653 -0.0205 0.0147 0.164 0.7844 0.98 0.952 1.01 -0.0101 0.0416 0.807 0.09288 0.99 0.912 1.07 0.0366 0.0413 0.375 0.4256 1.04 0.957 1.12 -0.0679 0.042 0.106 0.9755 0.934 0.861 1.01 PRS_PLINK_1e.04 338.2 Chronic pain Both 4454 14303 6 neurological darkblue 14303, 4454 3576, 1091 3576, 1068 3575, 1159 3576, 1135 0.0172 0.0173 0.319 0.4959 1.02 0.983 1.05 -0.0319 0.0494 0.518 0.2854 0.969 0.879 1.07 0.0538 0.0487 0.269 0.5702 1.06 0.959 1.16 0.0257 0.0488 0.598 0.2231 1.03 0.932 1.13 PRS_PLINK_1e.04 339 Other headache syndromes Both 4428 17398 6 neurological darkblue 17398, 4428 4350, 1090 4349, 1078 4349, 1157 4350, 1102 0.00286 0.0173 0.869 0.06107 1 0.969 1.04 -0.0178 0.0492 0.718 0.144 0.982 0.892 1.08 0.0496 0.0485 0.307 0.5133 1.05 0.955 1.16 0.000164 0.049 0.997 0.00116 1 0.909 1.1 PRS_PLINK_1e.04 340 Migraine Both 3533 16153 6 neurological darkblue 16153, 3533 4039, 833 4038, 902 4038, 904 4038, 893 0.0141 0.0191 0.461 0.3362 1.01 0.977 1.05 0.0743 0.0543 0.171 0.7665 1.08 0.968 1.2 0.0757 0.0542 0.163 0.7888 1.08 0.97 1.2 0.0523 0.0544 0.336 0.4742 1.05 0.947 1.17 PRS_PLINK_1e.04 340.1 Migrain with aura Both 1902 12862 6 neurological darkblue 12862, 1902 3216, 447 3215, 501 3215, 477 3216, 477 0.0109 0.0248 0.661 0.1795 1.01 0.963 1.06 0.115 0.0701 0.102 0.9923 1.12 0.978 1.29 0.0658 0.0708 0.352 0.4528 1.07 0.93 1.23 0.0566 0.0709 0.424 0.3723 1.06 0.921 1.22 PRS_PLINK_1e.04 341 Other demyelinating diseases of central nervous system Both 59 735 6 neurological darkblue 735, 59 184, 8 184, 15 183, 17 184, 19 0.166 0.13 0.202 0.6938 1.18 0.915 1.52 0.499 0.429 0.245 0.6103 1.65 0.71 3.82 0.847 0.422 0.0445 1.351 2.33 1.02 5.33 0.823 0.404 0.0416 1.381 2.28 1.03 5.02 PRS_PLINK_1e.04 342 Hemiplegia Both 120 2050 6 neurological darkblue 2050, 120 513, 24 512, 28 512, 31 513, 37 0.178 0.0941 0.0577 1.239 1.2 0.994 1.44 0.161 0.275 0.558 0.2536 1.17 0.686 2.01 0.237 0.27 0.38 0.4203 1.27 0.746 2.15 0.427 0.263 0.104 0.9833 1.53 0.916 2.57 PRS_PLINK_1e.04 343 Infantile cerebral palsy Both 56 573 6 neurological darkblue 573, 56 144, 18 143, 11 143, 16 143, 11 -0.12 0.136 0.378 0.4221 0.887 0.68 1.16 -0.499 0.381 0.191 0.7193 0.607 0.288 1.28 -0.165 0.358 0.646 0.1899 0.848 0.42 1.71 -0.518 0.391 0.185 0.7322 0.596 0.277 1.28 PRS_PLINK_1e.04 344 Other paralytic syndromes Both 245 3268 6 neurological darkblue 3268, 245 817, 61 817, 55 817, 56 817, 72 -0.00139 0.0662 0.983 0.007365 0.999 0.877 1.14 -0.114 0.19 0.549 0.2602 0.892 0.615 1.3 -0.0875 0.189 0.644 0.1912 0.916 0.632 1.33 0.167 0.179 0.351 0.455 1.18 0.832 1.68 PRS_PLINK_1e.04 345 Epilepsy, recurrent seizures, convulsions Both 1095 13790 6 neurological darkblue 13790, 1095 3448, 256 3447, 296 3447, 277 3448, 266 0.0254 0.0316 0.421 0.3757 1.03 0.964 1.09 0.141 0.0885 0.11 0.9592 1.15 0.969 1.37 0.0755 0.0898 0.401 0.397 1.08 0.904 1.29 0.0419 0.0906 0.644 0.1913 1.04 0.873 1.25 PRS_PLINK_1e.04 345.1 Epilepsy Both 349 4134 6 neurological darkblue 4134, 349 1034, 67 1033, 93 1033, 96 1034, 93 0.101 0.0559 0.0699 1.155 1.11 0.992 1.23 0.32 0.165 0.0515 1.288 1.38 0.998 1.9 0.355 0.164 0.03 1.523 1.43 1.03 1.97 0.332 0.165 0.0436 1.361 1.39 1.01 1.93 PRS_PLINK_1e.04 345.11 Generalized convulsive epilepsy Both 128 1420 6 neurological darkblue 1420, 128 355, 27 355, 32 355, 35 355, 34 0.0421 0.0909 0.643 0.1918 1.04 0.873 1.25 0.137 0.269 0.61 0.2149 1.15 0.677 1.94 0.255 0.262 0.33 0.4818 1.29 0.773 2.16 0.235 0.265 0.375 0.4255 1.26 0.753 2.12 PRS_PLINK_1e.04 345.12 Partial epilepsy Both 256 2923 6 neurological darkblue 2923, 256 731, 43 731, 69 730, 70 731, 74 0.158 0.0669 0.0178 1.75 1.17 1.03 1.34 0.466 0.198 0.0186 1.73 1.59 1.08 2.35 0.469 0.198 0.0177 1.751 1.6 1.08 2.36 0.541 0.196 0.0057 2.244 1.72 1.17 2.52 PRS_PLINK_1e.04 345.3 Convulsions Both 1023 13013 6 neurological darkblue 13013, 1023 3254, 241 3253, 272 3253, 261 3253, 249 0.0283 0.0326 0.385 0.4143 1.03 0.965 1.1 0.116 0.0916 0.207 0.6843 1.12 0.938 1.34 0.0756 0.0925 0.414 0.3834 1.08 0.9 1.29 0.0372 0.0934 0.691 0.1607 1.04 0.864 1.25 PRS_PLINK_1e.04 346 Abnormal findings on study of brain and/or nervous system Both 72 903 6 neurological darkblue 903, 72 226, 14 226, 19 225, 20 226, 19 0.0863 0.121 0.474 0.3239 1.09 0.861 1.38 0.346 0.35 0.322 0.4922 1.41 0.712 2.81 0.254 0.348 0.466 0.3313 1.29 0.651 2.55 0.249 0.348 0.475 0.3237 1.28 0.648 2.54 PRS_PLINK_1e.04 346.1 Nonspecific abnormal findings on radiological and other examination of skull and head Both 511 6536 6 neurological darkblue 6536, 511 1634, 112 1634, 145 1634, 123 1634, 131 0.0532 0.0461 0.249 0.6046 1.05 0.963 1.15 0.268 0.13 0.0392 1.407 1.31 1.01 1.69 0.0951 0.134 0.478 0.3203 1.1 0.846 1.43 0.164 0.133 0.217 0.6636 1.18 0.908 1.53 PRS_PLINK_1e.04 346.2 Nonspecific abnormal results of function study of brain and central nervous system Both 47 582 6 neurological darkblue 582, 47 146, 8 145, 9 145, 15 146, 15 0.231 0.151 0.127 0.8953 1.26 0.936 1.69 0.138 0.457 0.763 0.1175 1.15 0.468 2.81 0.526 0.434 0.226 0.6455 1.69 0.722 3.96 0.518 0.422 0.219 0.6592 1.68 0.735 3.84 PRS_PLINK_1e.04 346.3 Nonspecific abnormal findings in cerebrospinal fluid Both 36 562 6 neurological darkblue 562, 36 141, 9 140, 7 140, 10 141, 10 0.116 0.163 0.478 0.3206 1.12 0.815 1.55 -0.346 0.481 0.472 0.3259 0.708 0.276 1.82 -0.000662 0.443 0.999 0.0005184 0.999 0.42 2.38 0.0732 0.438 0.867 0.06186 1.08 0.456 2.54 PRS_PLINK_1e.04 347 Cataplexy and narcolepsy Both 51 631 6 neurological darkblue 631, 51 158, 9 158, 12 157, 13 158, 17 0.0919 0.148 0.535 0.2718 1.1 0.82 1.47 0.253 0.423 0.55 0.2595 1.29 0.562 2.95 0.25 0.418 0.549 0.2608 1.28 0.567 2.91 0.519 0.401 0.196 0.7087 1.68 0.766 3.69 PRS_PLINK_1e.04 348 Other conditions of brain Both 618 9092 6 neurological darkblue 9092, 618 2273, 135 2273, 146 2273, 175 2273, 162 0.0702 0.0416 0.0911 1.041 1.07 0.989 1.16 0.082 0.122 0.503 0.2987 1.09 0.854 1.38 0.264 0.118 0.025 1.601 1.3 1.03 1.64 0.184 0.12 0.123 0.91 1.2 0.951 1.52 PRS_PLINK_1e.04 348.2 Cerebral edema and compression of brain Both 381 4899 6 neurological darkblue 4899, 381 1225, 86 1225, 89 1224, 110 1225, 96 0.0499 0.0537 0.353 0.4528 1.05 0.946 1.17 0.0323 0.155 0.835 0.0784 1.03 0.762 1.4 0.246 0.149 0.0977 1.01 1.28 0.956 1.71 0.115 0.153 0.451 0.3461 1.12 0.832 1.51 PRS_PLINK_1e.04 348.4 Cerebral cysts Both 117 1352 6 neurological darkblue 1352, 117 338, 27 338, 32 338, 26 338, 32 0.0247 0.0953 0.796 0.09923 1.02 0.85 1.24 0.193 0.267 0.47 0.3281 1.21 0.719 2.05 -0.056 0.278 0.84 0.07566 0.946 0.549 1.63 0.124 0.268 0.644 0.1913 1.13 0.669 1.91 PRS_PLINK_1e.04 348.7 Coma Both 84 1147 6 neurological darkblue 1147, 84 287, 16 287, 25 286, 29 287, 14 -0.0246 0.11 0.822 0.08491 0.976 0.787 1.21 0.4 0.322 0.215 0.668 1.49 0.793 2.81 0.557 0.313 0.0749 1.125 1.75 0.946 3.22 -0.0726 0.357 0.839 0.07634 0.93 0.462 1.87 PRS_PLINK_1e.04 348.8 Encephalopathy, not elsewhere classified Both 170 3681 6 neurological darkblue 3681, 170 921, 27 920, 45 920, 54 920, 44 0.182 0.08 0.0233 1.633 1.2 1.03 1.4 0.53 0.241 0.0281 1.551 1.7 1.06 2.72 0.659 0.234 0.00492 2.308 1.93 1.22 3.06 0.477 0.242 0.0489 1.311 1.61 1 2.59 PRS_PLINK_1e.04 348.9 Other conditions of brain, NOS Both 911 11389 6 neurological darkblue 11389, 911 2848, 211 2847, 240 2847, 244 2847, 216 0.0394 0.0344 0.252 0.5989 1.04 0.972 1.11 0.131 0.0977 0.181 0.7432 1.14 0.941 1.38 0.148 0.0973 0.128 0.8918 1.16 0.958 1.4 0.0244 0.1 0.807 0.09292 1.02 0.842 1.25 PRS_PLINK_1e.04 349 Other and unspecified disorders of the nervous system Both 341 4664 6 neurological darkblue 4664, 341 1166, 78 1166, 89 1166, 87 1166, 87 0.0201 0.0558 0.719 0.1435 1.02 0.915 1.14 0.136 0.159 0.393 0.4057 1.15 0.839 1.56 0.111 0.159 0.486 0.3135 1.12 0.818 1.53 0.118 0.16 0.459 0.3383 1.13 0.823 1.54 PRS_PLINK_1e.04 350 Abnormal movement Both 2218 20240 6 neurological darkblue 20240, 2218 5060, 542 5060, 565 5060, 584 5060, 526 -0.00702 0.0224 0.754 0.1226 0.993 0.95 1.04 0.0459 0.0635 0.469 0.3286 1.05 0.925 1.19 0.0716 0.0631 0.256 0.5911 1.07 0.949 1.22 -0.0344 0.0645 0.594 0.2264 0.966 0.851 1.1 PRS_PLINK_1e.04 350.1 Abnormal involuntary movements Both 1113 14398 6 neurological darkblue 14398, 1113 3600, 268 3599, 273 3599, 295 3600, 276 0.00695 0.0309 0.822 0.085 1.01 0.948 1.07 0.0229 0.0889 0.797 0.0985 1.02 0.86 1.22 0.103 0.0874 0.24 0.6201 1.11 0.934 1.32 0.0349 0.0887 0.694 0.1585 1.04 0.87 1.23 PRS_PLINK_1e.04 350.2 Abnormality of gait Both 1083 13864 6 neurological darkblue 13864, 1083 3466, 261 3466, 275 3466, 296 3466, 250 -0.0127 0.0314 0.686 0.1636 0.987 0.928 1.05 0.0572 0.0894 0.522 0.2821 1.06 0.889 1.26 0.13 0.0881 0.141 0.8519 1.14 0.958 1.35 -0.0386 0.0915 0.673 0.1721 0.962 0.804 1.15 PRS_PLINK_1e.04 350.3 Lack of coordination Both 382 5015 6 neurological darkblue 5015, 382 1254, 104 1254, 109 1253, 85 1254, 84 -0.102 0.053 0.0534 1.273 0.903 0.814 1 0.0427 0.142 0.764 0.1171 1.04 0.79 1.38 -0.211 0.151 0.161 0.7929 0.81 0.603 1.09 -0.204 0.151 0.176 0.7543 0.816 0.607 1.1 PRS_PLINK_1e.04 350.5 Abnormal reflex Both 84 945 6 neurological darkblue 945, 84 237, 16 236, 16 236, 22 236, 30 0.232 0.116 0.0446 1.35 1.26 1.01 1.58 -0.0373 0.349 0.915 0.03867 0.963 0.487 1.91 0.319 0.33 0.334 0.4767 1.38 0.721 2.63 0.619 0.312 0.0471 1.327 1.86 1.01 3.42 PRS_PLINK_1e.04 350.6 Disturbances of sensation of smell and taste Both 229 2510 6 neurological darkblue 2510, 229 628, 63 627, 53 627, 52 628, 61 -0.0771 0.0682 0.258 0.5881 0.926 0.81 1.06 -0.169 0.193 0.381 0.4191 0.845 0.579 1.23 -0.186 0.194 0.336 0.4743 0.83 0.568 1.21 -0.0179 0.187 0.924 0.03449 0.982 0.681 1.42 PRS_PLINK_1e.04 351 Other peripheral nerve disorders Both 2661 18107 6 neurological darkblue 18107, 2661 4527, 657 4527, 656 4526, 642 4527, 705 0.00918 0.0209 0.66 0.1802 1.01 0.969 1.05 -0.00156 0.0593 0.979 0.009198 0.998 0.889 1.12 -0.0281 0.0596 0.637 0.1957 0.972 0.865 1.09 0.0659 0.0584 0.259 0.586 1.07 0.953 1.2 PRS_PLINK_1e.04 352 Disorders of other cranial nerves Both 753 8290 6 neurological darkblue 8290, 753 2073, 187 2072, 196 2072, 179 2073, 191 0.0055 0.0376 0.884 0.05359 1.01 0.934 1.08 0.0508 0.106 0.633 0.1987 1.05 0.854 1.3 -0.0348 0.109 0.749 0.1256 0.966 0.781 1.2 0.0275 0.107 0.798 0.09819 1.03 0.833 1.27 PRS_PLINK_1e.04 352.1 Trigeminal nerve disorders [CN5] Both 240 2692 6 neurological darkblue 2692, 240 673, 56 673, 69 673, 67 673, 48 -0.0425 0.0668 0.525 0.2802 0.958 0.841 1.09 0.213 0.186 0.251 0.6001 1.24 0.86 1.78 0.176 0.188 0.35 0.4565 1.19 0.825 1.72 -0.167 0.202 0.406 0.3913 0.846 0.57 1.26 PRS_PLINK_1e.04 352.2 Facial nerve disorders [CN7] Both 310 3632 6 neurological darkblue 3632, 310 908, 78 908, 87 908, 70 908, 75 0.00088 0.0576 0.988 0.005323 1 0.894 1.12 0.108 0.162 0.506 0.2963 1.11 0.811 1.53 -0.104 0.169 0.54 0.2674 0.901 0.647 1.26 -0.0117 0.167 0.944 0.02484 0.988 0.712 1.37 PRS_PLINK_1e.04 353 Nerve root and plexus disorders Both 1664 17150 6 neurological darkblue 17150, 1664 4288, 405 4287, 417 4287, 404 4288, 437 0.0166 0.0257 0.518 0.2854 1.02 0.967 1.07 0.0301 0.0729 0.68 0.1676 1.03 0.893 1.19 -0.00438 0.0735 0.952 0.02117 0.996 0.862 1.15 0.0747 0.0722 0.301 0.5212 1.08 0.935 1.24 PRS_PLINK_1e.04 353.1 Nerve plexus lesions Both 191 2221 6 neurological darkblue 2221, 191 556, 56 555, 44 555, 40 555, 51 -0.0116 0.0766 0.88 0.05554 0.989 0.851 1.15 -0.251 0.207 0.223 0.6511 0.778 0.519 1.17 -0.31 0.212 0.144 0.8425 0.733 0.484 1.11 -0.0913 0.199 0.647 0.189 0.913 0.618 1.35 PRS_PLINK_1e.04 353.2 Nerve root lesions Both 45 563 6 neurological darkblue 563, 45 141, 16 141, 7 140, 11 141, 11 -0.151 0.147 0.303 0.5188 0.86 0.644 1.15 -0.904 0.443 0.0412 1.386 0.405 0.17 0.964 -0.535 0.403 0.184 0.7341 0.586 0.266 1.29 -0.386 0.397 0.33 0.4817 0.679 0.312 1.48 PRS_PLINK_1e.04 355 Complex regional/central pain syndrome Both 234 2934 6 neurological darkblue 2934, 234 734, 65 733, 50 733, 63 734, 56 -0.0159 0.0672 0.813 0.09003 0.984 0.863 1.12 -0.238 0.192 0.215 0.6667 0.788 0.541 1.15 -0.0279 0.182 0.878 0.05634 0.973 0.681 1.39 -0.132 0.188 0.482 0.3166 0.877 0.607 1.27 PRS_PLINK_1e.04 355.1 Chronic pain syndrome Both 288 4434 6 neurological darkblue 4434, 288 1109, 58 1108, 80 1108, 67 1109, 82 0.0999 0.0616 0.105 0.9796 1.11 0.979 1.25 0.337 0.175 0.0547 1.262 1.4 0.993 1.98 0.168 0.182 0.355 0.45 1.18 0.828 1.69 0.345 0.175 0.0484 1.315 1.41 1 1.99 PRS_PLINK_1e.04 356 Hereditary and idiopathic peripheral neuropathy Both 538 8567 6 neurological darkblue 8567, 538 2142, 133 2142, 136 2141, 139 2142, 130 -0.0324 0.0443 0.465 0.3329 0.968 0.888 1.06 0.0314 0.125 0.802 0.09589 1.03 0.807 1.32 0.0415 0.124 0.739 0.1315 1.04 0.817 1.33 -0.00582 0.126 0.963 0.01626 0.994 0.776 1.27 PRS_PLINK_1e.04 357 Inflammatory and toxic neuropathy Both 857 12989 6 neurological darkblue 12989, 857 3248, 218 3247, 216 3247, 230 3247, 193 -0.0491 0.035 0.161 0.7924 0.952 0.889 1.02 -0.00204 0.0988 0.984 0.007211 0.998 0.822 1.21 0.0507 0.0975 0.603 0.2195 1.05 0.869 1.27 -0.118 0.102 0.245 0.6104 0.889 0.728 1.08 PRS_PLINK_1e.04 358 Myoneural disorders Both 394 5230 6 neurological darkblue 5230, 394 1308, 103 1307, 89 1307, 95 1308, 107 0.0212 0.0527 0.688 0.1622 1.02 0.921 1.13 -0.145 0.149 0.329 0.4831 0.865 0.647 1.16 -0.0763 0.146 0.602 0.2203 0.927 0.696 1.23 0.0409 0.142 0.774 0.1112 1.04 0.788 1.38 PRS_PLINK_1e.04 358.1 Myasthenia gravis Both 37 473 6 neurological darkblue 473, 37 119, 9 118, 5 118, 14 118, 9 0.0168 0.172 0.922 0.03535 1.02 0.726 1.42 -0.467 0.516 0.365 0.4377 0.627 0.228 1.72 0.455 0.437 0.298 0.5258 1.58 0.669 3.72 -0.0417 0.457 0.927 0.0328 0.959 0.392 2.35 PRS_PLINK_1e.04 359 Muscular dystrophies and other myopathies Both 435 5321 6 neurological darkblue 5321, 435 1331, 106 1330, 124 1330, 99 1330, 106 -0.00087 0.0495 0.986 0.006142 0.999 0.907 1.1 0.156 0.137 0.253 0.5961 1.17 0.894 1.53 -0.0699 0.144 0.628 0.2023 0.933 0.703 1.24 -0.00248 0.142 0.986 0.006106 0.998 0.756 1.32 PRS_PLINK_1e.04 359.1 Muscular dystrophies Both 22 327 6 neurological darkblue 327, 22 82, 7 82, 10 81, 3 82, 2 -0.317 0.203 0.119 0.9227 0.728 0.489 1.09 0.37 0.498 0.457 0.3399 1.45 0.546 3.84 -0.804 0.642 0.21 0.678 0.447 0.127 1.57 -0.992 0.706 0.16 0.7962 0.371 0.093 1.48 PRS_PLINK_1e.04 359.2 Myopathy Both 420 5133 6 neurological darkblue 5133, 420 1284, 101 1283, 118 1283, 98 1283, 103 0.00905 0.0505 0.858 0.06654 1.01 0.914 1.11 0.159 0.14 0.258 0.5887 1.17 0.89 1.54 -0.0264 0.146 0.857 0.06705 0.974 0.731 1.3 0.0184 0.144 0.899 0.04642 1.02 0.768 1.35 PRS_PLINK_1e.04 360 Disorders of the globe Both 41 509 7 sense organs darkseagreen4 509, 41 128, 6 127, 14 127, 11 127, 10 0.138 0.162 0.392 0.4064 1.15 0.837 1.58 0.75 0.458 0.102 0.9928 2.12 0.862 5.2 0.703 0.488 0.15 0.825 2.02 0.776 5.25 0.391 0.497 0.431 0.3658 1.48 0.559 3.91 PRS_PLINK_1e.04 360.2 Progressive myopia Both 25 274 7 sense organs darkseagreen4 274, 25 69, 4 68, 8 68, 8 69, 5 0.17 0.203 0.402 0.3955 1.19 0.796 1.77 0.751 0.583 0.198 0.7034 2.12 0.675 6.65 0.626 0.575 0.276 0.5583 1.87 0.606 5.77 -0.0329 0.625 0.958 0.01864 0.968 0.284 3.3 PRS_PLINK_1e.04 361 Retinal detachments and defects Both 215 2680 7 sense organs darkseagreen4 2680, 215 670, 53 670, 60 670, 64 670, 38 -0.0547 0.07 0.434 0.3626 0.947 0.825 1.09 0.1 0.194 0.604 0.2187 1.11 0.756 1.62 0.183 0.191 0.338 0.4709 1.2 0.826 1.74 -0.339 0.215 0.115 0.941 0.712 0.467 1.09 PRS_PLINK_1e.04 361.1 Retinal detachment with retinal defect Both 94 1113 7 sense organs darkseagreen4 1113, 94 279, 19 278, 25 278, 30 278, 20 0.0277 0.106 0.793 0.1005 1.03 0.836 1.26 0.252 0.304 0.408 0.3897 1.29 0.709 2.33 0.397 0.299 0.184 0.7353 1.49 0.828 2.67 0.0501 0.319 0.875 0.05785 1.05 0.563 1.96 PRS_PLINK_1e.04 362 Other retinal disorders Both 806 9457 7 sense organs darkseagreen4 9457, 806 2365, 181 2364, 218 2364, 220 2364, 187 0.0125 0.0368 0.734 0.1344 1.01 0.942 1.09 0.189 0.105 0.0716 1.145 1.21 0.984 1.48 0.19 0.105 0.0688 1.163 1.21 0.985 1.48 0.0253 0.108 0.815 0.08907 1.03 0.83 1.27 PRS_PLINK_1e.04 362.2 Degeneration of macula and posterior pole of retina Both 451 5511 7 sense organs darkseagreen4 5511, 451 1378, 107 1378, 116 1377, 130 1378, 98 -0.0106 0.0488 0.829 0.08167 0.989 0.899 1.09 0.0663 0.139 0.633 0.1986 1.07 0.814 1.4 0.184 0.136 0.174 0.7599 1.2 0.922 1.57 -0.109 0.144 0.448 0.3488 0.896 0.676 1.19 PRS_PLINK_1e.04 362.21 Macular degeneration, dry Both 57 946 7 sense organs darkseagreen4 946, 57 237, 14 236, 10 236, 18 237, 15 0.102 0.133 0.444 0.3526 1.11 0.853 1.44 -0.421 0.396 0.287 0.5414 0.656 0.302 1.43 0.191 0.357 0.593 0.2267 1.21 0.601 2.44 0.0612 0.363 0.866 0.06241 1.06 0.522 2.17 PRS_PLINK_1e.04 362.22 Macular degeneration, wet Both 16 321 7 sense organs darkseagreen4 321, 16 81, 5 80, 5 80, 4 80, 2 -0.184 0.24 0.444 0.3531 0.832 0.519 1.33 -0.355 0.666 0.594 0.2259 0.701 0.19 2.59 -0.365 0.621 0.557 0.2543 0.694 0.205 2.35 -0.461 0.68 0.498 0.3027 0.631 0.166 2.39 PRS_PLINK_1e.04 362.23 Cystoid macular degeneration of retina Both 103 1253 7 sense organs darkseagreen4 1253, 103 314, 23 313, 26 313, 36 313, 18 0.0178 0.105 0.866 0.06264 1.02 0.828 1.25 0.136 0.288 0.637 0.196 1.15 0.651 2.02 0.434 0.272 0.11 0.9572 1.54 0.906 2.63 -0.282 0.312 0.366 0.4364 0.754 0.409 1.39 PRS_PLINK_1e.04 362.26 Macular puckering of retina Both 195 2875 7 sense organs darkseagreen4 2875, 195 719, 54 719, 56 718, 49 719, 36 -0.0837 0.0735 0.255 0.594 0.92 0.796 1.06 -0.00219 0.196 0.991 0.003897 0.998 0.68 1.46 -0.12 0.202 0.552 0.258 0.887 0.597 1.32 -0.451 0.218 0.039 1.409 0.637 0.415 0.978 PRS_PLINK_1e.04 362.27 Drusen (degenerative) of retina Both 117 1472 7 sense organs darkseagreen4 1472, 117 368, 27 368, 27 368, 28 368, 35 0.0606 0.0967 0.531 0.2752 1.06 0.879 1.28 -0.00743 0.273 0.978 0.009542 0.993 0.582 1.69 0.0356 0.275 0.897 0.04723 1.04 0.604 1.78 0.247 0.261 0.344 0.464 1.28 0.768 2.13 PRS_PLINK_1e.04 362.29 Macular degeneration (senile) of retina NOS Both 389 4798 7 sense organs darkseagreen4 4798, 389 1200, 93 1199, 99 1199, 104 1200, 93 -0.00754 0.0526 0.886 0.05253 0.992 0.895 1.1 0.0442 0.149 0.768 0.1149 1.05 0.78 1.4 0.0871 0.148 0.557 0.2544 1.09 0.816 1.46 -0.0327 0.152 0.829 0.08136 0.968 0.719 1.3 PRS_PLINK_1e.04 362.3 Other nondiabetic retinopathy Both 155 3194 7 sense organs darkseagreen4 3194, 155 799, 34 798, 44 798, 42 799, 35 0.0266 0.081 0.743 0.1292 1.03 0.876 1.2 0.262 0.228 0.25 0.6023 1.3 0.832 2.03 0.199 0.231 0.389 0.4102 1.22 0.776 1.92 0.0137 0.239 0.954 0.02025 1.01 0.634 1.62 PRS_PLINK_1e.04 362.31 Separation of retinal layers Both 119 1534 7 sense organs darkseagreen4 1534, 119 384, 23 383, 33 383, 38 384, 25 0.0289 0.0933 0.757 0.1209 1.03 0.857 1.24 0.356 0.273 0.192 0.716 1.43 0.836 2.44 0.48 0.267 0.0719 1.143 1.62 0.958 2.73 0.0297 0.287 0.918 0.03739 1.03 0.587 1.81 PRS_PLINK_1e.04 362.4 Retinal vascular changes and abnomalities Both 116 2061 7 sense organs darkseagreen4 2061, 116 516, 30 515, 29 515, 28 515, 29 -0.00839 0.0932 0.928 0.03231 0.992 0.826 1.19 -0.0384 0.264 0.884 0.05337 0.962 0.574 1.61 -0.0233 0.263 0.929 0.03177 0.977 0.584 1.64 0.0059 0.262 0.982 0.007889 1.01 0.602 1.68 PRS_PLINK_1e.04 362.6 Peripheral retinal degenerations Both 131 1605 7 sense organs darkseagreen4 1605, 131 402, 28 401, 47 401, 32 401, 24 -0.0853 0.0871 0.328 0.4846 0.918 0.774 1.09 0.519 0.244 0.033 1.482 1.68 1.04 2.71 0.13 0.261 0.619 0.2082 1.14 0.682 1.9 -0.159 0.277 0.567 0.2464 0.853 0.496 1.47 PRS_PLINK_1e.04 362.7 Hereditary retinal dystrophies Both 69 837 7 sense organs darkseagreen4 837, 69 210, 11 209, 19 209, 14 209, 25 0.247 0.128 0.0536 1.271 1.28 0.996 1.64 0.514 0.375 0.171 0.7671 1.67 0.801 3.49 0.238 0.388 0.539 0.268 1.27 0.593 2.71 0.761 0.357 0.0332 1.478 2.14 1.06 4.31 PRS_PLINK_1e.04 362.8 Retinal hemorrhage/ischemia Both 60 864 7 sense organs darkseagreen4 864, 60 216, 11 216, 13 216, 21 216, 15 0.101 0.127 0.43 0.3668 1.11 0.862 1.42 0.0888 0.393 0.821 0.08557 1.09 0.506 2.36 0.702 0.369 0.057 1.244 2.02 0.979 4.16 0.268 0.384 0.485 0.314 1.31 0.616 2.77 PRS_PLINK_1e.04 362.9 Retinal edema Both 63 1020 7 sense organs darkseagreen4 1020, 63 255, 12 255, 16 255, 21 255, 14 0.0224 0.131 0.864 0.06357 1.02 0.791 1.32 0.258 0.373 0.49 0.3096 1.29 0.622 2.69 0.532 0.356 0.136 0.868 1.7 0.847 3.42 0.0665 0.385 0.863 0.06409 1.07 0.503 2.27 PRS_PLINK_1e.04 363 Chorioretinal inflammations, scars, and other disorders of choroid Both 145 1755 7 sense organs darkseagreen4 1755, 145 439, 34 439, 43 438, 33 439, 35 0.0246 0.0872 0.778 0.1089 1.02 0.864 1.22 0.211 0.235 0.369 0.4326 1.23 0.779 1.96 -0.0244 0.247 0.921 0.03551 0.976 0.601 1.58 0.0126 0.245 0.959 0.01815 1.01 0.626 1.64 PRS_PLINK_1e.04 363.3 Chorioretinal scars Both 93 1149 7 sense organs darkseagreen4 1149, 93 288, 18 287, 28 287, 24 287, 23 0.0482 0.109 0.658 0.1814 1.05 0.847 1.3 0.386 0.303 0.204 0.6913 1.47 0.811 2.67 0.298 0.312 0.339 0.4692 1.35 0.731 2.48 0.216 0.315 0.494 0.3064 1.24 0.669 2.3 PRS_PLINK_1e.04 364 Corneal opacity and other disorders of cornea Both 375 4437 7 sense organs darkseagreen4 4437, 375 1110, 82 1109, 104 1109, 98 1109, 91 -0.0216 0.0534 0.686 0.1638 0.979 0.881 1.09 0.241 0.153 0.114 0.9437 1.27 0.944 1.72 0.188 0.154 0.222 0.6531 1.21 0.892 1.63 0.0904 0.157 0.564 0.2488 1.09 0.805 1.49 PRS_PLINK_1e.04 364.1 Corneal opacity Both 135 1702 7 sense organs darkseagreen4 1702, 135 426, 32 425, 41 425, 29 426, 33 -0.0733 0.0876 0.402 0.3953 0.929 0.783 1.1 0.274 0.242 0.257 0.5894 1.32 0.818 2.12 -0.0863 0.261 0.741 0.1303 0.917 0.55 1.53 0.0582 0.252 0.818 0.08745 1.06 0.646 1.74 PRS_PLINK_1e.04 364.2 Corneal edema Both 38 493 7 sense organs darkseagreen4 493, 38 124, 10 123, 10 123, 7 123, 11 0.0329 0.153 0.83 0.08114 1.03 0.766 1.4 0.0782 0.435 0.858 0.06676 1.08 0.461 2.54 -0.252 0.477 0.597 0.2242 0.777 0.305 1.98 0.163 0.426 0.703 0.1532 1.18 0.511 2.71 PRS_PLINK_1e.04 364.4 Corneal degenerations Both 163 1763 7 sense organs darkseagreen4 1763, 163 441, 35 441, 50 440, 44 441, 34 -0.0189 0.0849 0.824 0.08433 0.981 0.831 1.16 0.37 0.23 0.107 0.9695 1.45 0.923 2.27 0.242 0.235 0.302 0.5203 1.27 0.804 2.02 -0.0314 0.246 0.898 0.04649 0.969 0.599 1.57 PRS_PLINK_1e.04 364.41 Keratoconus Both 32 338 7 sense organs darkseagreen4 338, 32 85, 9 84, 9 84, 8 85, 6 -0.0654 0.188 0.727 0.1384 0.937 0.649 1.35 0.309 0.52 0.553 0.2575 1.36 0.491 3.77 -0.125 0.499 0.803 0.09544 0.883 0.332 2.35 -0.245 0.525 0.641 0.1929 0.783 0.28 2.19 PRS_PLINK_1e.04 364.5 Corneal dystrophy Both 126 1546 7 sense organs darkseagreen4 1546, 126 387, 36 386, 23 386, 37 387, 30 -0.124 0.0906 0.171 0.7663 0.883 0.74 1.06 -0.435 0.27 0.108 0.9682 0.647 0.381 1.1 0.018 0.242 0.941 0.02652 1.02 0.634 1.63 -0.203 0.253 0.421 0.3754 0.816 0.497 1.34 PRS_PLINK_1e.04 364.51 Fuchs' dystrophy Both 68 801 7 sense organs darkseagreen4 801, 68 201, 18 200, 12 200, 15 200, 23 -0.062 0.123 0.615 0.2113 0.94 0.738 1.2 -0.408 0.368 0.267 0.5731 0.665 0.324 1.37 -0.193 0.347 0.578 0.2381 0.824 0.418 1.63 0.134 0.324 0.679 0.1678 1.14 0.605 2.16 PRS_PLINK_1e.04 364.9 Cornea replaced by transplant Both 23 282 7 sense organs darkseagreen4 282, 23 71, 5 70, 5 70, 6 71, 7 0.134 0.211 0.526 0.2789 1.14 0.756 1.73 0.0417 0.622 0.947 0.02385 1.04 0.308 3.53 0.272 0.594 0.647 0.1892 1.31 0.41 4.21 0.417 0.567 0.462 0.3356 1.52 0.5 4.61 PRS_PLINK_1e.04 365 Glaucoma Both 719 8560 7 sense organs darkseagreen4 8560, 719 2140, 165 2140, 174 2140, 219 2140, 161 0.0261 0.0389 0.503 0.2984 1.03 0.951 1.11 0.0569 0.113 0.613 0.2123 1.06 0.849 1.32 0.281 0.108 0.00902 2.045 1.32 1.07 1.64 -0.0195 0.115 0.865 0.06316 0.981 0.783 1.23 PRS_PLINK_1e.04 365.1 Open-angle glaucoma Both 175 2172 7 sense organs darkseagreen4 2172, 175 543, 47 543, 31 543, 54 543, 43 0.0358 0.0765 0.639 0.1942 1.04 0.892 1.2 -0.393 0.235 0.0947 1.024 0.675 0.426 1.07 0.157 0.206 0.446 0.3502 1.17 0.781 1.75 -0.0583 0.216 0.787 0.1038 0.943 0.618 1.44 PRS_PLINK_1e.04 365.11 Primary open angle glaucoma Both 96 1098 7 sense organs darkseagreen4 1098, 96 275, 25 274, 16 274, 28 275, 27 0.0767 0.109 0.481 0.3174 1.08 0.872 1.34 -0.426 0.32 0.183 0.737 0.653 0.349 1.22 0.0948 0.284 0.739 0.1315 1.1 0.63 1.92 0.0811 0.283 0.774 0.1111 1.08 0.623 1.89 PRS_PLINK_1e.04 365.2 Primary angle-closure glaucoma Both 62 822 7 sense organs darkseagreen4 822, 62 206, 23 205, 17 205, 14 206, 8 -0.265 0.128 0.0376 1.425 0.767 0.597 0.985 -0.268 0.325 0.41 0.3875 0.765 0.405 1.45 -0.492 0.343 0.151 0.8219 0.611 0.312 1.2 -0.987 0.4 0.0137 1.864 0.373 0.17 0.817 PRS_PLINK_1e.04 366 Cataract Both 2075 12994 7 sense organs darkseagreen4 12994, 2075 3249, 508 3248, 512 3248, 545 3249, 510 0.0222 0.0248 0.37 0.4313 1.02 0.974 1.07 -0.0323 0.0708 0.649 0.1879 0.968 0.843 1.11 0.0469 0.0699 0.502 0.2992 1.05 0.914 1.2 -0.0254 0.0709 0.72 0.1429 0.975 0.848 1.12 PRS_PLINK_1e.04 366.1 Nonsenile Cataract Both 46 674 7 sense organs darkseagreen4 674, 46 169, 15 168, 14 168, 8 169, 9 -0.129 0.148 0.382 0.4176 0.879 0.657 1.17 -0.123 0.381 0.748 0.1263 0.885 0.419 1.87 -0.573 0.428 0.18 0.7446 0.564 0.244 1.3 -0.419 0.403 0.299 0.5249 0.658 0.298 1.45 PRS_PLINK_1e.04 366.2 Senile cataract Both 1271 10894 7 sense organs darkseagreen4 10894, 1271 2724, 320 2723, 317 2723, 336 2724, 298 -0.00369 0.0306 0.904 0.04383 0.996 0.938 1.06 -0.0419 0.0863 0.628 0.2023 0.959 0.81 1.14 0.0381 0.0854 0.655 0.1835 1.04 0.879 1.23 -0.0968 0.0876 0.269 0.5698 0.908 0.765 1.08 PRS_PLINK_1e.04 367 Disorders of refraction and accommodation; blindness and low vision Both 3566 19873 7 sense organs darkseagreen4 19873, 3566 4968, 886 4968, 915 4968, 899 4968, 866 -0.00846 0.0185 0.648 0.1886 0.992 0.956 1.03 0.0369 0.0521 0.479 0.3199 1.04 0.937 1.15 0.0123 0.0523 0.813 0.08967 1.01 0.914 1.12 -0.0217 0.0528 0.681 0.1666 0.979 0.882 1.09 PRS_PLINK_1e.04 367.1 Myopia Both 2261 18169 7 sense organs darkseagreen4 18169, 2261 4542, 568 4542, 577 4542, 556 4542, 560 -0.00378 0.0226 0.867 0.0619 0.996 0.953 1.04 0.0256 0.0634 0.686 0.1635 1.03 0.906 1.16 -0.0242 0.064 0.705 0.1519 0.976 0.861 1.11 -0.00777 0.0639 0.903 0.04425 0.992 0.876 1.12 PRS_PLINK_1e.04 367.2 Astigmatism Both 1778 16392 7 sense organs darkseagreen4 16392, 1778 4097, 446 4098, 448 4098, 444 4098, 440 -0.00266 0.0251 0.916 0.03818 0.997 0.949 1.05 0.0116 0.071 0.87 0.06026 1.01 0.88 1.16 -0.00435 0.0712 0.951 0.0217 0.996 0.866 1.14 -0.0062 0.0713 0.931 0.03121 0.994 0.864 1.14 PRS_PLINK_1e.04 367.8 Hypermetropia Both 753 8272 7 sense organs darkseagreen4 8272, 753 2068, 189 2068, 193 2068, 209 2068, 162 -0.0246 0.0381 0.517 0.2864 0.976 0.906 1.05 0.019 0.107 0.859 0.06591 1.02 0.827 1.26 0.106 0.105 0.311 0.5073 1.11 0.905 1.37 -0.154 0.111 0.166 0.7793 0.857 0.689 1.07 PRS_PLINK_1e.04 367.9 Blindness and low vision Both 378 5418 7 sense organs darkseagreen4 5418, 378 1355, 87 1354, 106 1354, 90 1355, 95 0.019 0.053 0.72 0.1426 1.02 0.919 1.13 0.195 0.149 0.19 0.7219 1.22 0.908 1.63 0.0279 0.154 0.856 0.06739 1.03 0.76 1.39 0.0917 0.152 0.546 0.2625 1.1 0.814 1.48 PRS_PLINK_1e.04 368 Visual disturbances Both 2077 20239 7 sense organs darkseagreen4 20239, 2077 5059, 498 5060, 536 5059, 564 5060, 479 0.00447 0.0231 0.846 0.07238 1 0.96 1.05 0.0704 0.0654 0.282 0.5504 1.07 0.944 1.22 0.122 0.0648 0.0599 1.223 1.13 0.995 1.28 -0.0459 0.0671 0.494 0.3061 0.955 0.837 1.09 PRS_PLINK_1e.04 368.1 Amblyopia Both 258 3085 7 sense organs darkseagreen4 3085, 258 772, 57 771, 64 771, 68 771, 69 0.0719 0.0648 0.267 0.5733 1.07 0.946 1.22 0.109 0.186 0.558 0.253 1.12 0.774 1.61 0.17 0.184 0.355 0.4493 1.19 0.827 1.7 0.187 0.183 0.308 0.511 1.21 0.841 1.73 PRS_PLINK_1e.04 368.2 Diplopia and disorders of binocular vision Both 385 4674 7 sense organs darkseagreen4 4674, 385 1168, 104 1168, 109 1168, 90 1169, 82 -0.0674 0.0525 0.199 0.7005 0.935 0.843 1.04 0.0487 0.142 0.732 0.1357 1.05 0.795 1.39 -0.14 0.149 0.346 0.4606 0.869 0.649 1.16 -0.227 0.152 0.135 0.8697 0.797 0.591 1.07 PRS_PLINK_1e.04 368.3 Anisometropia Both 91 965 7 sense organs darkseagreen4 965, 91 242, 20 241, 27 241, 25 241, 19 0.0307 0.11 0.781 0.1075 1.03 0.831 1.28 0.274 0.298 0.358 0.4457 1.32 0.733 2.36 0.252 0.303 0.407 0.3903 1.29 0.71 2.33 0.0108 0.321 0.973 0.01181 1.01 0.539 1.9 PRS_PLINK_1e.04 368.4 Visual field defects Both 308 4414 7 sense organs darkseagreen4 4414, 308 1104, 55 1103, 83 1103, 87 1104, 83 0.112 0.0598 0.0618 1.209 1.12 0.995 1.26 0.412 0.177 0.0199 1.701 1.51 1.07 2.13 0.461 0.175 0.00852 2.07 1.59 1.12 2.24 0.412 0.177 0.0198 1.704 1.51 1.07 2.13 PRS_PLINK_1e.04 368.9 Subjective visual disturbances Both 366 4795 7 sense organs darkseagreen4 4795, 366 1199, 89 1199, 94 1198, 103 1199, 80 -0.0242 0.0548 0.659 0.181 0.976 0.877 1.09 0.057 0.152 0.708 0.15 1.06 0.786 1.43 0.153 0.149 0.307 0.5123 1.16 0.869 1.56 -0.0919 0.158 0.562 0.2506 0.912 0.669 1.24 PRS_PLINK_1e.04 368.91 Psychophysical visual disturbances Both 28 435 7 sense organs darkseagreen4 435, 28 109, 6 109, 8 108, 10 109, 4 -0.158 0.191 0.406 0.392 0.853 0.587 1.24 0.424 0.54 0.432 0.364 1.53 0.53 4.41 0.404 0.521 0.439 0.3577 1.5 0.539 4.16 -0.511 0.608 0.4 0.3978 0.6 0.182 1.97 PRS_PLINK_1e.04 369 Infection of the eye Both 1436 15164 7 sense organs darkseagreen4 15164, 1436 3791, 342 3791, 366 3791, 366 3791, 361 0.0229 0.0278 0.41 0.3876 1.02 0.969 1.08 0.0715 0.0787 0.364 0.4393 1.07 0.921 1.25 0.0698 0.0787 0.375 0.4257 1.07 0.919 1.25 0.0613 0.0789 0.438 0.3589 1.06 0.911 1.24 PRS_PLINK_1e.04 369.2 Eye infection, viral Both 221 2434 7 sense organs darkseagreen4 2434, 221 609, 56 608, 71 608, 43 609, 51 -0.0995 0.0687 0.148 0.831 0.905 0.791 1.04 0.227 0.186 0.221 0.6551 1.25 0.872 1.81 -0.256 0.207 0.218 0.662 0.774 0.516 1.16 -0.133 0.199 0.505 0.2964 0.876 0.592 1.29 PRS_PLINK_1e.04 369.5 Conjunctivitis, infectious Both 1242 13524 7 sense organs darkseagreen4 13524, 1242 3381, 290 3381, 311 3381, 326 3381, 314 0.0427 0.03 0.155 0.8087 1.04 0.984 1.11 0.0741 0.0852 0.385 0.415 1.08 0.911 1.27 0.121 0.0844 0.152 0.8186 1.13 0.957 1.33 0.0833 0.085 0.327 0.4854 1.09 0.92 1.28 PRS_PLINK_1e.04 370 Keratitis Both 512 5853 7 sense organs darkseagreen4 5853, 512 1464, 121 1463, 151 1463, 125 1463, 115 -0.0236 0.0459 0.607 0.2165 0.977 0.893 1.07 0.229 0.127 0.071 1.148 1.26 0.981 1.61 0.0402 0.132 0.761 0.1187 1.04 0.804 1.35 -0.0462 0.134 0.731 0.1361 0.955 0.734 1.24 PRS_PLINK_1e.04 370.1 Corneal ulcer Both 91 1060 7 sense organs darkseagreen4 1060, 91 265, 20 265, 33 265, 15 265, 23 -0.0548 0.106 0.607 0.217 0.947 0.769 1.17 0.488 0.294 0.0966 1.015 1.63 0.916 2.9 -0.28 0.343 0.414 0.3831 0.755 0.386 1.48 0.126 0.311 0.686 0.1638 1.13 0.616 2.09 PRS_PLINK_1e.04 370.2 Superficial keratitis Both 209 2281 7 sense organs darkseagreen4 2281, 209 571, 47 570, 56 570, 58 570, 48 -0.00398 0.0734 0.957 0.0192 0.996 0.863 1.15 0.17 0.203 0.402 0.3959 1.19 0.796 1.77 0.219 0.202 0.279 0.5546 1.25 0.837 1.85 0.00931 0.21 0.965 0.01565 1.01 0.669 1.52 PRS_PLINK_1e.04 370.3 Keratoconjunctivitis Both 220 2632 7 sense organs darkseagreen4 2632, 220 658, 52 658, 66 658, 57 658, 45 -0.00805 0.0688 0.907 0.04248 0.992 0.867 1.14 0.23 0.191 0.227 0.6443 1.26 0.867 1.83 0.0857 0.196 0.663 0.1787 1.09 0.741 1.6 -0.154 0.207 0.458 0.3395 0.857 0.571 1.29 PRS_PLINK_1e.04 370.31 Keratoconjunctivitis sicca Both 52 683 7 sense organs darkseagreen4 683, 52 171, 7 171, 18 170, 15 171, 12 0.101 0.14 0.469 0.3287 1.11 0.841 1.46 0.888 0.428 0.0382 1.418 2.43 1.05 5.62 0.723 0.43 0.0925 1.034 2.06 0.887 4.79 0.435 0.444 0.327 0.4857 1.55 0.647 3.69 PRS_PLINK_1e.04 371 Inflammation of the eye Both 1593 15580 7 sense organs darkseagreen4 15580, 1593 3895, 393 3895, 400 3895, 411 3895, 388 -0.0113 0.0264 0.67 0.174 0.989 0.939 1.04 0.0171 0.0747 0.818 0.08702 1.02 0.879 1.18 0.0405 0.0742 0.585 0.2328 1.04 0.9 1.2 -0.0189 0.0752 0.801 0.09628 0.981 0.847 1.14 PRS_PLINK_1e.04 371.1 Uveitis, noninfectious or NOS Both 187 2274 7 sense organs darkseagreen4 2274, 187 569, 43 568, 52 568, 54 569, 38 -0.0315 0.0752 0.675 0.1705 0.969 0.836 1.12 0.167 0.212 0.43 0.3667 1.18 0.78 1.79 0.244 0.211 0.247 0.6073 1.28 0.844 1.93 -0.138 0.226 0.543 0.2653 0.871 0.559 1.36 PRS_PLINK_1e.04 371.2 Conjunctivitis, noninfectious Both 377 4450 7 sense organs darkseagreen4 4450, 377 1113, 96 1112, 90 1112, 94 1113, 96 -0.00662 0.0536 0.902 0.04489 0.993 0.894 1.1 -0.0669 0.152 0.659 0.1812 0.935 0.695 1.26 -0.0114 0.15 0.939 0.02716 0.989 0.737 1.33 0.00688 0.149 0.963 0.01627 1.01 0.752 1.35 PRS_PLINK_1e.04 371.21 Allergic conjunctivitis Both 320 3779 7 sense organs darkseagreen4 3779, 320 945, 79 945, 76 944, 79 945, 85 0.0186 0.0583 0.75 0.1249 1.02 0.909 1.14 -0.0404 0.166 0.807 0.0929 0.96 0.694 1.33 0.0301 0.165 0.855 0.06807 1.03 0.746 1.42 0.0696 0.162 0.666 0.1762 1.07 0.781 1.47 PRS_PLINK_1e.04 371.3 Inflammation of eyelids Both 1142 12133 7 sense organs darkseagreen4 12133, 1142 3034, 278 3033, 285 3033, 298 3033, 281 0.00305 0.0311 0.922 0.03534 1 0.944 1.07 0.0284 0.088 0.747 0.1266 1.03 0.866 1.22 0.0665 0.0872 0.446 0.3511 1.07 0.901 1.27 0.00328 0.0883 0.97 0.01309 1 0.844 1.19 PRS_PLINK_1e.04 371.33 Noninfectious dermatoses of eyelid Both 65 674 7 sense organs darkseagreen4 674, 65 169, 14 168, 23 168, 20 169, 8 -0.173 0.134 0.196 0.7083 0.841 0.647 1.09 0.477 0.349 0.172 0.7656 1.61 0.813 3.19 0.418 0.356 0.24 0.6196 1.52 0.756 3.05 -0.441 0.421 0.295 0.5309 0.643 0.282 1.47 PRS_PLINK_1e.04 372 Disorders of conjunctiva Both 370 4330 7 sense organs darkseagreen4 4330, 370 1083, 78 1082, 107 1082, 98 1083, 87 0.0612 0.0556 0.271 0.5669 1.06 0.953 1.19 0.303 0.154 0.0488 1.312 1.35 1 1.83 0.231 0.157 0.139 0.8559 1.26 0.927 1.71 0.101 0.16 0.528 0.2774 1.11 0.808 1.51 PRS_PLINK_1e.04 374 Other disorders of eyelids Both 957 10366 7 sense organs darkseagreen4 10366, 957 2592, 230 2591, 254 2591, 238 2592, 235 0.0185 0.0338 0.584 0.2333 1.02 0.953 1.09 0.0987 0.095 0.299 0.525 1.1 0.916 1.33 0.0329 0.0964 0.733 0.1351 1.03 0.856 1.25 0.0186 0.0967 0.847 0.07197 1.02 0.843 1.23 PRS_PLINK_1e.04 374.1 Ectropion or entropion Both 127 1426 7 sense organs darkseagreen4 1426, 127 357, 28 356, 33 356, 29 357, 37 0.0584 0.0943 0.536 0.2708 1.06 0.881 1.28 0.184 0.262 0.482 0.3173 1.2 0.72 2.01 0.0487 0.269 0.856 0.06731 1.05 0.62 1.78 0.301 0.256 0.239 0.6215 1.35 0.819 2.23 PRS_PLINK_1e.04 374.2 Lagophthalmos Both 96 1060 7 sense organs darkseagreen4 1060, 96 265, 19 265, 29 265, 29 265, 19 -0.045 0.103 0.66 0.1802 0.956 0.782 1.17 0.433 0.298 0.146 0.8354 1.54 0.86 2.76 0.361 0.298 0.227 0.6441 1.43 0.799 2.57 -0.00409 0.326 0.99 0.004368 0.996 0.525 1.89 PRS_PLINK_1e.04 374.3 Ptosis of eyelid Both 323 4032 7 sense organs darkseagreen4 4032, 323 1008, 65 1008, 92 1008, 88 1008, 78 0.0605 0.0578 0.295 0.5299 1.06 0.949 1.19 0.364 0.167 0.0291 1.536 1.44 1.04 1.99 0.315 0.168 0.0602 1.221 1.37 0.987 1.9 0.167 0.172 0.333 0.4778 1.18 0.843 1.66 PRS_PLINK_1e.04 374.6 Dermatochalasis Both 248 3212 7 sense organs darkseagreen4 3212, 248 803, 63 803, 60 803, 63 803, 62 0.00696 0.0664 0.917 0.03785 1.01 0.884 1.15 -0.0428 0.185 0.817 0.08784 0.958 0.667 1.38 0.0155 0.183 0.933 0.03027 1.02 0.709 1.45 -0.0121 0.184 0.947 0.02345 0.988 0.689 1.42 PRS_PLINK_1e.04 375 Disorders of lacrimal system Both 1202 12138 7 sense organs darkseagreen4 12138, 1202 3034, 307 3034, 307 3034, 311 3035, 277 -0.0167 0.0303 0.581 0.2357 0.983 0.927 1.04 -0.000188 0.0851 0.998 0.0007672 1 0.846 1.18 0.013 0.0848 0.878 0.05638 1.01 0.858 1.2 -0.113 0.087 0.196 0.7087 0.894 0.753 1.06 PRS_PLINK_1e.04 375.1 Dry eyes Both 1297 12510 7 sense organs darkseagreen4 12510, 1297 3127, 322 3127, 327 3127, 342 3128, 306 -0.00318 0.0294 0.914 0.03909 0.997 0.941 1.06 0.0142 0.0832 0.865 0.06317 1.01 0.862 1.19 0.0609 0.0823 0.459 0.3381 1.06 0.905 1.25 -0.0542 0.0841 0.52 0.2842 0.947 0.803 1.12 PRS_PLINK_1e.04 375.2 Epiphora Both 156 1783 7 sense organs darkseagreen4 1783, 156 446, 43 446, 38 445, 42 446, 33 -0.0806 0.081 0.319 0.4959 0.923 0.787 1.08 -0.115 0.228 0.615 0.2111 0.891 0.57 1.39 -0.0399 0.223 0.858 0.06647 0.961 0.621 1.49 -0.28 0.237 0.237 0.6251 0.756 0.475 1.2 PRS_PLINK_1e.04 376 Disorders of the orbit Both 174 1787 7 sense organs darkseagreen4 1787, 174 447, 51 447, 49 446, 45 447, 29 -0.164 0.0778 0.0348 1.458 0.849 0.729 0.988 -0.0412 0.209 0.844 0.07384 0.96 0.637 1.45 -0.121 0.214 0.572 0.2424 0.886 0.582 1.35 -0.515 0.238 0.0305 1.516 0.597 0.375 0.953 PRS_PLINK_1e.04 377 Disorders of optic nerve and visual pathways Both 354 4262 7 sense organs darkseagreen4 4262, 354 1066, 95 1065, 93 1065, 90 1066, 76 -0.075 0.0546 0.169 0.7712 0.928 0.834 1.03 -0.00962 0.151 0.949 0.02261 0.99 0.736 1.33 -0.0385 0.153 0.801 0.09661 0.962 0.714 1.3 -0.218 0.159 0.169 0.7712 0.804 0.589 1.1 PRS_PLINK_1e.04 377.1 Optic atrophy Both 97 1153 7 sense organs darkseagreen4 1153, 97 289, 25 288, 26 288, 28 288, 18 -0.0694 0.104 0.503 0.2983 0.933 0.761 1.14 0.0529 0.284 0.852 0.06961 1.05 0.605 1.84 0.147 0.281 0.601 0.2213 1.16 0.668 2.01 -0.285 0.31 0.357 0.4474 0.752 0.41 1.38 PRS_PLINK_1e.04 377.3 Optic neuritis/neuropathy Both 232 2857 7 sense organs darkseagreen4 2857, 232 715, 61 714, 58 714, 58 714, 55 -0.0424 0.0682 0.534 0.2727 0.958 0.839 1.1 -0.0441 0.188 0.815 0.08887 0.957 0.662 1.38 -0.0367 0.188 0.845 0.07291 0.964 0.666 1.39 -0.0935 0.191 0.625 0.204 0.911 0.626 1.33 PRS_PLINK_1e.04 378 Strabismus and other disorders of binocular eye movements Both 503 5990 7 sense organs darkseagreen4 5990, 503 1497, 124 1497, 109 1497, 140 1498, 130 0.0362 0.0466 0.438 0.3588 1.04 0.946 1.14 -0.123 0.136 0.364 0.4385 0.884 0.678 1.15 0.133 0.128 0.299 0.5239 1.14 0.889 1.47 0.0435 0.13 0.738 0.1318 1.04 0.809 1.35 PRS_PLINK_1e.04 378.1 Strabismus (not specified as paralytic) Both 329 3908 7 sense organs darkseagreen4 3908, 329 977, 82 977, 67 977, 96 977, 84 0.0222 0.0582 0.703 0.1531 1.02 0.912 1.15 -0.175 0.169 0.301 0.5219 0.839 0.602 1.17 0.172 0.156 0.27 0.5686 1.19 0.875 1.61 0.0231 0.16 0.885 0.05291 1.02 0.748 1.4 PRS_PLINK_1e.04 378.2 Nystagmus and other irregular eye movements Both 78 863 7 sense organs darkseagreen4 863, 78 216, 22 216, 14 215, 16 216, 26 0.0501 0.119 0.672 0.1724 1.05 0.833 1.33 -0.391 0.345 0.258 0.5887 0.677 0.344 1.33 -0.305 0.336 0.364 0.4393 0.737 0.382 1.42 0.196 0.302 0.517 0.2865 1.22 0.673 2.2 PRS_PLINK_1e.04 378.5 Paralytic strabismus Both 130 1592 7 sense organs darkseagreen4 1592, 130 398, 34 398, 38 398, 29 398, 29 0.0467 0.091 0.608 0.2161 1.05 0.877 1.25 0.0806 0.242 0.739 0.1314 1.08 0.675 1.74 -0.18 0.257 0.485 0.3143 0.836 0.505 1.38 -0.153 0.256 0.551 0.2586 0.858 0.519 1.42 PRS_PLINK_1e.04 379 Other disorders of eye Both 1515 13994 7 sense organs darkseagreen4 13994, 1515 3499, 371 3498, 394 3498, 380 3499, 370 0.0142 0.0273 0.602 0.2201 1.01 0.961 1.07 0.0612 0.0767 0.425 0.3715 1.06 0.915 1.24 0.0282 0.0776 0.717 0.1446 1.03 0.883 1.2 -0.00181 0.0778 0.981 0.008152 0.998 0.857 1.16 PRS_PLINK_1e.04 379.1 Scleritis and episcleritis Both 75 942 7 sense organs darkseagreen4 942, 75 236, 21 235, 16 235, 19 236, 19 -0.0299 0.118 0.801 0.0966 0.971 0.77 1.22 -0.263 0.332 0.429 0.3676 0.769 0.401 1.47 -0.0893 0.316 0.778 0.1093 0.915 0.492 1.7 -0.0887 0.322 0.783 0.1063 0.915 0.487 1.72 PRS_PLINK_1e.04 379.2 Disorders of vitreous body Both 979 9550 7 sense organs darkseagreen4 9550, 979 2388, 238 2387, 259 2387, 246 2388, 236 0.009 0.0338 0.79 0.1024 1.01 0.944 1.08 0.0699 0.0948 0.461 0.336 1.07 0.89 1.29 0.0248 0.0961 0.796 0.09913 1.03 0.849 1.24 -0.0145 0.0965 0.88 0.05529 0.986 0.816 1.19 PRS_PLINK_1e.04 379.3 Aphakia and other disorders of lens Both 38 466 7 sense organs darkseagreen4 466, 38 117, 8 116, 10 116, 9 117, 11 0.0704 0.168 0.674 0.1711 1.07 0.773 1.49 0.231 0.456 0.613 0.2126 1.26 0.515 3.08 0.0566 0.467 0.904 0.04405 1.06 0.424 2.64 0.376 0.454 0.408 0.3891 1.46 0.598 3.55 PRS_PLINK_1e.04 379.4 Anomalies of pupillary function Both 99 1269 7 sense organs darkseagreen4 1269, 99 318, 29 317, 20 317, 28 317, 22 -0.1 0.0995 0.313 0.5039 0.905 0.744 1.1 -0.355 0.291 0.222 0.6532 0.701 0.396 1.24 -0.0584 0.272 0.83 0.08099 0.943 0.554 1.61 -0.293 0.286 0.306 0.5145 0.746 0.426 1.31 PRS_PLINK_1e.04 379.5 Disorders of iris and ciliary body Both 101 1202 7 sense organs darkseagreen4 1202, 101 301, 27 300, 25 300, 29 301, 20 -0.078 0.103 0.45 0.3465 0.925 0.755 1.13 -0.0867 0.284 0.76 0.1192 0.917 0.526 1.6 0.051 0.273 0.852 0.06948 1.05 0.616 1.8 -0.318 0.301 0.291 0.5359 0.728 0.403 1.31 PRS_PLINK_1e.04 379.51 Pigmentary iris degeneration Both 34 324 7 sense organs darkseagreen4 324, 34 81, 10 81, 9 81, 11 81, 4 -0.275 0.168 0.101 0.9955 0.759 0.547 1.06 -0.125 0.491 0.799 0.09743 0.882 0.337 2.31 0.129 0.45 0.774 0.1112 1.14 0.471 2.75 -0.877 0.581 0.131 0.8813 0.416 0.133 1.3 PRS_PLINK_1e.04 379.9 Pain, swelling or discharge of eye Both 454 5680 7 sense organs darkseagreen4 5680, 454 1420, 125 1420, 100 1420, 107 1420, 122 0.0163 0.0494 0.742 0.1296 1.02 0.923 1.12 -0.22 0.139 0.112 0.9505 0.802 0.612 1.05 -0.142 0.136 0.297 0.5273 0.868 0.664 1.13 -0.0159 0.132 0.904 0.04373 0.984 0.76 1.28 PRS_PLINK_1e.04 380 Disorders of external ear Both 767 8347 7 sense organs darkseagreen4 8347, 767 2087, 201 2087, 186 2086, 193 2087, 187 -0.0361 0.0374 0.335 0.4751 0.965 0.896 1.04 -0.0842 0.106 0.427 0.37 0.919 0.747 1.13 -0.0413 0.105 0.694 0.1585 0.96 0.781 1.18 -0.0698 0.106 0.51 0.2927 0.933 0.758 1.15 PRS_PLINK_1e.04 380.1 Otitis externa Both 590 7185 7 sense organs darkseagreen4 7185, 590 1797, 140 1796, 162 1796, 147 1796, 141 -0.00223 0.0432 0.959 0.01829 0.998 0.917 1.09 0.14 0.119 0.24 0.6203 1.15 0.911 1.45 0.0492 0.122 0.687 0.1633 1.05 0.827 1.33 0.00343 0.123 0.978 0.009739 1 0.788 1.28 PRS_PLINK_1e.04 380.4 Impacted cerumen Both 914 10023 7 sense organs darkseagreen4 10023, 914 2506, 239 2506, 226 2505, 227 2506, 222 -0.0474 0.0342 0.166 0.7796 0.954 0.892 1.02 -0.0585 0.0967 0.545 0.2636 0.943 0.78 1.14 -0.0487 0.0967 0.615 0.2112 0.953 0.788 1.15 -0.0732 0.0971 0.451 0.3457 0.929 0.768 1.12 PRS_PLINK_1e.04 381 Otitis media and Eustachian tube disorders Both 2081 19198 7 sense organs darkseagreen4 19198, 2081 4799, 485 4799, 537 4799, 533 4800, 526 0.0278 0.0232 0.231 0.6363 1.03 0.982 1.08 0.103 0.0659 0.118 0.9297 1.11 0.974 1.26 0.0998 0.066 0.131 0.883 1.1 0.971 1.26 0.0827 0.0663 0.212 0.673 1.09 0.954 1.24 PRS_PLINK_1e.04 381.1 Otitis media Both 1545 16610 7 sense organs darkseagreen4 16610, 1545 4152, 357 4152, 408 4152, 391 4153, 389 0.0319 0.0268 0.233 0.6323 1.03 0.98 1.09 0.132 0.0756 0.0805 1.094 1.14 0.984 1.32 0.0891 0.0764 0.243 0.6139 1.09 0.941 1.27 0.0837 0.0766 0.274 0.5619 1.09 0.936 1.26 PRS_PLINK_1e.04 381.11 Suppurative and unspecified otitis media Both 1317 14427 7 sense organs darkseagreen4 14427, 1317 3606, 314 3607, 345 3606, 329 3607, 329 0.0213 0.0289 0.461 0.3364 1.02 0.965 1.08 0.0942 0.0813 0.247 0.6074 1.1 0.937 1.29 0.0497 0.0822 0.546 0.2631 1.05 0.894 1.23 0.0406 0.0824 0.622 0.2064 1.04 0.886 1.22 PRS_PLINK_1e.04 381.2 Eustachian tube disorders Both 862 9326 7 sense organs darkseagreen4 9326, 862 2331, 203 2331, 214 2331, 241 2332, 204 -0.00271 0.0358 0.94 0.02705 0.997 0.93 1.07 0.0519 0.102 0.611 0.2142 1.05 0.862 1.29 0.173 0.0993 0.0806 1.094 1.19 0.979 1.44 -0.00404 0.103 0.969 0.01381 0.996 0.814 1.22 PRS_PLINK_1e.04 381.3 Mastoiditis & related conditions Both 76 799 7 sense organs darkseagreen4 799, 76 200, 17 200, 25 199, 18 200, 16 -0.043 0.119 0.718 0.1438 0.958 0.758 1.21 0.338 0.323 0.296 0.5288 1.4 0.744 2.64 0.0672 0.34 0.843 0.07395 1.07 0.549 2.08 -0.0224 0.35 0.949 0.02279 0.978 0.492 1.94 PRS_PLINK_1e.04 381.9 Otorrhea Both 168 1903 7 sense organs darkseagreen4 1903, 168 476, 37 476, 46 475, 40 476, 45 0.0337 0.0811 0.678 0.1691 1.03 0.882 1.21 0.221 0.226 0.329 0.4824 1.25 0.8 1.94 0.121 0.234 0.606 0.2172 1.13 0.713 1.79 0.218 0.229 0.341 0.4677 1.24 0.794 1.95 PRS_PLINK_1e.04 382 Otalgia Both 891 10246 7 sense organs darkseagreen4 10246, 891 2561, 204 2561, 229 2561, 248 2562, 210 -0.00207 0.0352 0.953 0.02092 0.998 0.931 1.07 0.118 0.0998 0.237 0.6253 1.13 0.925 1.37 0.198 0.0982 0.0439 1.358 1.22 1.01 1.48 0.0328 0.102 0.748 0.1262 1.03 0.846 1.26 PRS_PLINK_1e.04 383 Otosclerosis Both 74 639 7 sense organs darkseagreen4 639, 74 160, 19 160, 14 159, 23 160, 18 -0.0591 0.12 0.622 0.2062 0.943 0.745 1.19 -0.274 0.361 0.447 0.3495 0.76 0.375 1.54 0.288 0.33 0.382 0.4175 1.33 0.699 2.55 0.0123 0.342 0.971 0.01263 1.01 0.518 1.98 PRS_PLINK_1e.04 384 Other disorders of tympanic membrane Both 268 2909 7 sense organs darkseagreen4 2909, 268 728, 58 727, 81 727, 70 727, 59 -0.0527 0.064 0.41 0.3869 0.949 0.837 1.08 0.325 0.178 0.067 1.174 1.38 0.977 1.96 0.187 0.183 0.305 0.5159 1.21 0.843 1.72 0.0414 0.19 0.828 0.08207 1.04 0.718 1.51 PRS_PLINK_1e.04 384.1 Myringitis Both 26 283 7 sense organs darkseagreen4 283, 26 71, 4 71, 5 70, 9 71, 8 0.295 0.209 0.158 0.8011 1.34 0.892 2.02 0.348 0.619 0.574 0.2412 1.42 0.421 4.77 0.7 0.569 0.219 0.6602 2.01 0.66 6.14 0.558 0.572 0.33 0.482 1.75 0.569 5.36 PRS_PLINK_1e.04 384.4 Perforation of tympanic membrane Both 208 2297 7 sense organs darkseagreen4 2297, 208 575, 45 574, 60 574, 54 574, 49 -0.0476 0.072 0.508 0.294 0.953 0.828 1.1 0.286 0.203 0.158 0.8015 1.33 0.895 1.98 0.176 0.207 0.395 0.4034 1.19 0.795 1.79 0.12 0.212 0.573 0.2416 1.13 0.743 1.71 PRS_PLINK_1e.04 385 Other disorders of middle ear and mastoid Both 251 2408 7 sense organs darkseagreen4 2408, 251 602, 55 602, 65 602, 69 602, 62 -0.00439 0.067 0.948 0.0233 0.996 0.873 1.14 0.167 0.191 0.381 0.4185 1.18 0.813 1.72 0.237 0.189 0.21 0.6776 1.27 0.875 1.83 0.109 0.192 0.57 0.2445 1.12 0.766 1.62 PRS_PLINK_1e.04 385.3 Cholesteatoma Both 178 1619 7 sense organs darkseagreen4 1619, 178 404, 39 405, 51 404, 46 405, 42 -0.0147 0.078 0.85 0.07054 0.985 0.846 1.15 0.258 0.221 0.242 0.6153 1.29 0.84 1.99 0.174 0.227 0.445 0.3519 1.19 0.762 1.86 0.0646 0.23 0.779 0.1084 1.07 0.679 1.68 PRS_PLINK_1e.04 385.5 Tympanosclerosis and middle ear disease related to otitis media Both 75 689 7 sense organs darkseagreen4 689, 75 173, 17 172, 22 172, 20 172, 16 -0.0388 0.123 0.752 0.124 0.962 0.756 1.22 0.358 0.34 0.293 0.5329 1.43 0.734 2.79 0.218 0.342 0.524 0.2809 1.24 0.637 2.43 0.0199 0.356 0.955 0.01981 1.02 0.507 2.05 PRS_PLINK_1e.04 386 Vertiginous syndromes and other disorders of vestibular system Both 675 8232 7 sense organs darkseagreen4 8232, 675 2058, 164 2058, 181 2058, 164 2058, 166 -0.0152 0.0403 0.705 0.1516 0.985 0.91 1.07 0.0969 0.112 0.386 0.4136 1.1 0.885 1.37 0.0025 0.114 0.983 0.007642 1 0.802 1.25 0.0138 0.114 0.903 0.04417 1.01 0.811 1.27 PRS_PLINK_1e.04 386.1 Meniere's disease Both 117 1388 7 sense organs darkseagreen4 1388, 117 347, 24 347, 37 347, 23 347, 33 0.0409 0.0976 0.675 0.1706 1.04 0.86 1.26 0.452 0.267 0.0913 1.04 1.57 0.93 2.65 -0.0353 0.292 0.904 0.04394 0.965 0.545 1.71 0.32 0.272 0.239 0.6219 1.38 0.808 2.35 PRS_PLINK_1e.04 386.2 Peripheral or central vertigo Both 537 6772 7 sense organs darkseagreen4 6772, 537 1693, 129 1693, 144 1693, 128 1693, 136 -0.0123 0.045 0.785 0.1053 0.988 0.904 1.08 0.107 0.125 0.394 0.4049 1.11 0.87 1.42 -0.0141 0.129 0.913 0.03952 0.986 0.766 1.27 0.0496 0.127 0.696 0.1573 1.05 0.819 1.35 PRS_PLINK_1e.04 386.21 Central origin vertigo Both 423 5225 7 sense organs darkseagreen4 5225, 423 1307, 100 1306, 125 1306, 93 1306, 105 -0.0204 0.0508 0.688 0.1624 0.98 0.887 1.08 0.228 0.139 0.1 0.9987 1.26 0.957 1.65 -0.0668 0.148 0.652 0.1859 0.935 0.7 1.25 0.0498 0.144 0.729 0.1371 1.05 0.793 1.39 PRS_PLINK_1e.04 386.3 Labyrinthitis Both 550 6627 7 sense organs darkseagreen4 6627, 550 1657, 132 1657, 153 1656, 126 1657, 139 0.00221 0.0443 0.96 0.01761 1 0.919 1.09 0.148 0.123 0.229 0.6406 1.16 0.911 1.48 -0.0369 0.129 0.774 0.1111 0.964 0.749 1.24 0.056 0.126 0.656 0.1833 1.06 0.827 1.35 PRS_PLINK_1e.04 386.9 Dizziness and giddiness (Light-headedness and vertigo) Both 2529 19746 7 sense organs darkseagreen4 19746, 2529 4936, 634 4936, 613 4936, 668 4937, 614 -0.00567 0.0212 0.789 0.1027 0.994 0.954 1.04 -0.0374 0.0604 0.536 0.2712 0.963 0.856 1.08 0.0477 0.0593 0.421 0.3752 1.05 0.934 1.18 -0.0373 0.0604 0.537 0.27 0.963 0.856 1.08 PRS_PLINK_1e.04 388 Other disorders of ear Both 440 4802 7 sense organs darkseagreen4 4802, 440 1201, 112 1200, 114 1200, 120 1201, 94 -0.0671 0.0495 0.175 0.7565 0.935 0.849 1.03 0.0143 0.138 0.918 0.03734 1.01 0.774 1.33 0.0671 0.137 0.623 0.2056 1.07 0.818 1.4 -0.186 0.145 0.198 0.7037 0.83 0.625 1.1 PRS_PLINK_1e.04 389 Hearing loss Both 3045 20043 7 sense organs darkseagreen4 20043, 3045 5010, 779 5011, 761 5010, 788 5011, 717 -0.0292 0.0196 0.137 0.8646 0.971 0.935 1.01 -0.0184 0.0554 0.739 0.1313 0.982 0.881 1.09 0.0094 0.0551 0.864 0.06327 1.01 0.906 1.12 -0.0886 0.0562 0.115 0.9405 0.915 0.82 1.02 PRS_PLINK_1e.04 389.1 Sensorineural hearing loss Both 1446 13028 7 sense organs darkseagreen4 13028, 1446 3257, 371 3257, 354 3257, 382 3257, 339 -0.0243 0.0276 0.38 0.4203 0.976 0.925 1.03 -0.044 0.0784 0.575 0.2405 0.957 0.821 1.12 0.0299 0.0773 0.699 0.1555 1.03 0.886 1.2 -0.0828 0.0793 0.296 0.5288 0.92 0.788 1.08 PRS_PLINK_1e.04 389.2 Conductive hearing loss Both 505 5147 7 sense organs darkseagreen4 5147, 505 1287, 127 1287, 147 1286, 117 1287, 114 -0.0675 0.0468 0.149 0.8271 0.935 0.853 1.02 0.144 0.127 0.256 0.5915 1.15 0.901 1.48 -0.0776 0.133 0.56 0.2516 0.925 0.713 1.2 -0.112 0.134 0.405 0.3924 0.894 0.688 1.16 PRS_PLINK_1e.04 389.3 Degenerative and vascular disorders of ear Both 53 593 7 sense organs darkseagreen4 593, 53 149, 18 148, 18 148, 11 148, 6 -0.403 0.136 0.00311 2.507 0.668 0.511 0.873 0.0581 0.347 0.867 0.06206 1.06 0.537 2.09 -0.542 0.395 0.171 0.7682 0.582 0.268 1.26 -1.12 0.457 0.0147 1.834 0.328 0.134 0.803 PRS_PLINK_1e.04 389.4 Tinnitus Both 962 9927 7 sense organs darkseagreen4 9927, 962 2482, 240 2482, 241 2481, 243 2482, 238 -0.0278 0.0336 0.408 0.3889 0.973 0.911 1.04 0.00485 0.0952 0.959 0.01801 1 0.834 1.21 0.0112 0.095 0.906 0.043 1.01 0.84 1.22 -0.0108 0.0955 0.91 0.04091 0.989 0.82 1.19 PRS_PLINK_1e.04 389.5 Disorders of acoustic nerve Both 57 600 7 sense organs darkseagreen4 600, 57 150, 22 150, 12 150, 12 150, 11 -0.225 0.128 0.0777 1.11 0.798 0.621 1.03 -0.552 0.362 0.127 0.8962 0.576 0.283 1.17 -0.601 0.36 0.0951 1.022 0.548 0.271 1.11 -0.672 0.369 0.0684 1.165 0.51 0.248 1.05 PRS_PLINK_1e.04 394 Rheumatic disease of the heart valves Both 244 5156 8 circulatory system red 5156, 244 1289, 56 1289, 67 1289, 65 1289, 56 0.00199 0.0645 0.975 0.01085 1 0.883 1.14 0.206 0.183 0.261 0.5841 1.23 0.858 1.76 0.175 0.184 0.342 0.4657 1.19 0.83 1.71 0.0138 0.19 0.942 0.02577 1.01 0.698 1.47 PRS_PLINK_1e.04 394.1 Mitral valve stenosis and aortic valve stenosis Both 39 1115 8 circulatory system red 1115, 39 279, 4 279, 15 278, 10 279, 10 0.0796 0.157 0.613 0.2125 1.08 0.795 1.47 1.23 0.506 0.0154 1.812 3.4 1.26 9.18 0.689 0.517 0.182 0.7388 1.99 0.723 5.48 0.91 0.531 0.0866 1.062 2.48 0.877 7.03 PRS_PLINK_1e.04 394.2 Mitral valve disease Both 88 1643 8 circulatory system red 1643, 88 411, 20 411, 27 410, 24 411, 17 -0.00824 0.108 0.939 0.02725 0.992 0.803 1.23 0.334 0.294 0.256 0.5916 1.4 0.785 2.48 0.282 0.305 0.354 0.4511 1.33 0.73 2.41 -0.125 0.322 0.699 0.1554 0.883 0.469 1.66 PRS_PLINK_1e.04 394.3 Aortic valve disease Both 22 567 8 circulatory system red 567, 22 142, 5 142, 5 141, 9 142, 3 -0.046 0.196 0.814 0.08929 0.955 0.651 1.4 -0.166 0.577 0.774 0.1113 0.847 0.273 2.63 0.642 0.525 0.222 0.6544 1.9 0.679 5.32 -0.391 0.615 0.525 0.2798 0.676 0.203 2.26 PRS_PLINK_1e.04 394.4 Acute rheumatic heart disease Both 15 236 8 circulatory system red 236, 15 59, 3 59, 3 59, 2 59, 7 0.197 0.233 0.399 0.3987 1.22 0.77 1.92 -0.131 0.712 0.854 0.06859 0.877 0.217 3.54 -0.458 0.773 0.554 0.2569 0.633 0.139 2.88 0.768 0.643 0.232 0.6345 2.16 0.612 7.6 PRS_PLINK_1e.04 394.7 Disease of tricuspid valve Both 94 2200 8 circulatory system red 2200, 94 550, 24 550, 25 550, 21 550, 24 0.00069 0.101 0.995 0.002386 1 0.822 1.22 0.0972 0.283 0.732 0.1357 1.1 0.632 1.92 -0.0776 0.293 0.791 0.1016 0.925 0.521 1.64 0.0216 0.284 0.94 0.0271 1.02 0.585 1.78 PRS_PLINK_1e.04 395 Heart valve disorders Both 871 12897 8 circulatory system red 12897, 871 3224, 221 3224, 236 3224, 212 3224, 202 -0.0368 0.0346 0.288 0.5408 0.964 0.901 1.03 0.0613 0.0966 0.526 0.279 1.06 0.88 1.28 -0.0386 0.0991 0.697 0.157 0.962 0.792 1.17 -0.0869 0.1 0.385 0.4143 0.917 0.753 1.12 PRS_PLINK_1e.04 395.1 Nonrheumatic mitral valve disorders Both 569 8556 8 circulatory system red 8556, 569 2138, 139 2139, 161 2139, 141 2139, 128 -0.0402 0.0432 0.352 0.4536 0.961 0.883 1.05 0.146 0.119 0.221 0.6553 1.16 0.916 1.46 0.0245 0.123 0.842 0.07468 1.02 0.805 1.3 -0.0805 0.126 0.522 0.2825 0.923 0.721 1.18 PRS_PLINK_1e.04 395.2 Nonrheumatic aortic valve disorders Both 269 6479 8 circulatory system red 6479, 269 1620, 66 1620, 61 1619, 75 1620, 67 0.0297 0.0611 0.627 0.203 1.03 0.914 1.16 -0.0665 0.178 0.709 0.1492 0.936 0.66 1.33 0.138 0.171 0.42 0.3768 1.15 0.821 1.6 0.0355 0.175 0.839 0.07625 1.04 0.736 1.46 PRS_PLINK_1e.04 395.3 Nonrheumatic tricuspid valve disorders Both 91 1845 8 circulatory system red 1845, 91 462, 25 461, 25 461, 18 461, 23 -0.0262 0.105 0.802 0.09559 0.974 0.794 1.2 0.0506 0.282 0.857 0.06682 1.05 0.606 1.83 -0.253 0.308 0.411 0.3866 0.776 0.425 1.42 -0.0422 0.286 0.883 0.05421 0.959 0.547 1.68 PRS_PLINK_1e.04 395.4 Nonrheumatic pulmonary valve disorders Both 44 559 8 circulatory system red 559, 44 140, 11 140, 18 139, 5 140, 10 -0.0841 0.144 0.559 0.2526 0.919 0.693 1.22 0.438 0.382 0.252 0.5981 1.55 0.732 3.28 -0.77 0.52 0.139 0.8576 0.463 0.167 1.28 -0.0709 0.431 0.869 0.06083 0.932 0.4 2.17 PRS_PLINK_1e.04 395.6 Heart valve replaced Both 164 3887 8 circulatory system red 3887, 164 972, 49 972, 41 971, 38 972, 36 -0.0731 0.0766 0.34 0.469 0.929 0.8 1.08 -0.149 0.213 0.484 0.3149 0.861 0.567 1.31 -0.228 0.219 0.299 0.525 0.796 0.519 1.22 -0.273 0.22 0.216 0.6659 0.761 0.494 1.17 PRS_PLINK_1e.04 396 Abnormal heart sounds Both 1478 17288 8 circulatory system red 17288, 1478 4321, 369 4322, 387 4322, 370 4322, 352 -0.0279 0.027 0.301 0.5211 0.972 0.922 1.03 0.0502 0.0759 0.508 0.294 1.05 0.906 1.22 0.00474 0.0766 0.951 0.02195 1 0.865 1.17 -0.0461 0.0775 0.552 0.2578 0.955 0.82 1.11 PRS_PLINK_1e.04 401 Hypertension Both 0 23367 8 circulatory system red 23367, 0 5841 5842 5841 5842 -0.503 0.354 0.156 0.8072 0.605 0.302 1.21 0.207 0.841 0.806 0.09374 1.23 0.237 6.39 0.0536 0.836 0.949 0.02279 1.06 0.205 5.43 0.0189 0.844 0.982 0.007807 1.02 0.195 5.33 PRS_PLINK_1e.04 401.1 Essential hypertension Both 0 23364 8 circulatory system red 23364, 0 5840 5841 5841 5841 -0.503 0.355 0.156 0.8072 0.604 0.302 1.21 0.198 0.84 0.813 0.08964 1.22 0.235 6.33 0.0563 0.836 0.946 0.02397 1.06 0.206 5.44 0.0144 0.844 0.986 0.005963 1.01 0.194 5.31 PRS_PLINK_1e.04 401.2 Hypertensive heart and/or renal disease Both 0 14616 8 circulatory system red 14616, 0 3654 3654 3654 3654 -0.367 0.408 0.369 0.4335 0.693 0.312 1.54 0.221 0.882 0.802 0.09557 1.25 0.221 7.03 0.207 0.889 0.816 0.08817 1.23 0.215 7.02 0.258 0.897 0.774 0.1114 1.29 0.223 7.51 PRS_PLINK_1e.04 401.21 Hypertensive heart disease Both 0 6607 8 circulatory system red 6607, 0 1652 1652 1651 1652 -0.0238 0.43 0.956 0.01962 0.976 0.42 2.27 0.316 0.903 0.726 0.139 1.37 0.234 8.06 0.142 0.933 0.879 0.05602 1.15 0.185 7.17 0.167 0.896 0.852 0.06966 1.18 0.204 6.85 PRS_PLINK_1e.04 401.22 Hypertensive chronic kidney disease Both 0 13072 8 circulatory system red 13072, 0 3268 3268 3268 3268 -0.573 0.405 0.157 0.8036 0.564 0.255 1.25 0.161 0.922 0.861 0.06475 1.17 0.193 7.15 0.121 0.916 0.895 0.04806 1.13 0.187 6.79 0.152 0.92 0.868 0.06127 1.16 0.192 7.07 PRS_PLINK_1e.04 401.3 Other hypertensive complications Both 0 15833 8 circulatory system red 15833, 0 3959 3958 3958 3958 -0.303 0.403 0.451 0.3454 0.738 0.335 1.63 0.205 0.878 0.816 0.08853 1.23 0.22 6.86 0.253 0.885 0.775 0.1109 1.29 0.228 7.29 0.298 0.88 0.735 0.1336 1.35 0.24 7.55 PRS_PLINK_1e.04 411 Ischemic Heart Disease Both 1354 15898 8 circulatory system red 15898, 1354 3975, 319 3974, 314 3974, 388 3975, 333 0.0494 0.0287 0.0853 1.069 1.05 0.993 1.11 -0.000745 0.0836 0.993 0.003101 0.999 0.848 1.18 0.207 0.0798 0.00938 2.028 1.23 1.05 1.44 0.0503 0.0824 0.542 0.2664 1.05 0.895 1.24 PRS_PLINK_1e.04 411.1 Unstable angina (intermediate coronary syndrome) Both 54 3370 8 circulatory system red 3370, 54 843, 14 842, 16 842, 12 843, 12 0.0102 0.13 0.937 0.02812 1.01 0.783 1.3 0.192 0.347 0.579 0.2373 1.21 0.614 2.39 -0.0904 0.369 0.807 0.0933 0.914 0.443 1.88 -0.129 0.365 0.724 0.1404 0.879 0.43 1.8 PRS_PLINK_1e.04 411.2 Myocardial infarction Both 429 9929 8 circulatory system red 9929, 429 2483, 96 2482, 107 2482, 108 2482, 118 0.0988 0.0493 0.0448 1.348 1.1 1 1.22 0.116 0.142 0.413 0.384 1.12 0.85 1.48 0.118 0.142 0.405 0.3928 1.13 0.852 1.49 0.213 0.139 0.126 0.8997 1.24 0.942 1.63 PRS_PLINK_1e.04 411.3 Angina pectoris Both 266 8096 8 circulatory system red 8096, 266 2024, 62 2024, 66 2024, 74 2024, 64 0.0409 0.0616 0.506 0.2955 1.04 0.923 1.18 0.0609 0.177 0.731 0.1362 1.06 0.751 1.5 0.166 0.173 0.337 0.4727 1.18 0.841 1.66 0.0369 0.178 0.836 0.07797 1.04 0.732 1.47 PRS_PLINK_1e.04 411.4 Coronary atherosclerosis Both 997 13733 8 circulatory system red 13733, 997 3434, 228 3433, 225 3433, 303 3433, 241 0.0627 0.0332 0.0589 1.23 1.06 0.998 1.14 -0.00439 0.0978 0.964 0.01581 0.996 0.822 1.21 0.278 0.0917 0.00246 2.61 1.32 1.1 1.58 0.0563 0.0963 0.559 0.2529 1.06 0.876 1.28 PRS_PLINK_1e.04 411.41 Aneurysm and dissection of heart Both 23 635 8 circulatory system red 635, 23 159, 6 159, 4 158, 8 159, 5 0.00193 0.193 0.992 0.003485 1 0.687 1.46 -0.4 0.557 0.474 0.3246 0.671 0.225 2 0.256 0.499 0.608 0.2162 1.29 0.486 3.44 -0.0541 0.545 0.921 0.03582 0.947 0.326 2.76 PRS_PLINK_1e.04 411.8 Other chronic ischemic heart disease, unspecified Both 736 12498 8 circulatory system red 12498, 736 3125, 175 3124, 171 3124, 215 3125, 175 0.0512 0.0381 0.179 0.7484 1.05 0.977 1.13 -0.0109 0.111 0.922 0.03547 0.989 0.796 1.23 0.208 0.105 0.0478 1.321 1.23 1 1.51 0.0103 0.11 0.926 0.03348 1.01 0.814 1.25 PRS_PLINK_1e.04 411.9 Other acute and subacute forms of ischemic heart disease Both 49 1720 8 circulatory system red 1720, 49 430, 16 430, 10 430, 13 430, 10 -0.0784 0.135 0.561 0.2508 0.925 0.71 1.2 -0.495 0.38 0.192 0.7161 0.609 0.289 1.28 -0.215 0.356 0.546 0.2625 0.807 0.402 1.62 -0.45 0.377 0.233 0.6325 0.638 0.304 1.34 PRS_PLINK_1e.04 414 Other forms of chronic heart disease Both 498 10637 8 circulatory system red 10637, 498 2660, 130 2659, 117 2659, 130 2659, 121 -0.00437 0.0453 0.923 0.03473 0.996 0.911 1.09 -0.11 0.13 0.395 0.4038 0.896 0.695 1.15 -0.00266 0.126 0.983 0.007353 0.997 0.778 1.28 -0.0804 0.129 0.532 0.2737 0.923 0.717 1.19 PRS_PLINK_1e.04 414.2 ASCVD Both 107 2822 8 circulatory system red 2822, 107 706, 28 705, 27 705, 26 706, 26 -0.0325 0.0986 0.742 0.1296 0.968 0.798 1.17 -0.0682 0.267 0.798 0.09782 0.934 0.553 1.58 -0.0579 0.269 0.83 0.08104 0.944 0.557 1.6 -0.143 0.271 0.599 0.2224 0.867 0.51 1.48 PRS_PLINK_1e.04 415 Pulmonary heart disease Both 784 13102 8 circulatory system red 13102, 784 3276, 187 3275, 199 3275, 213 3276, 185 -0.0172 0.0368 0.64 0.1938 0.983 0.915 1.06 0.062 0.104 0.553 0.2576 1.06 0.867 1.31 0.133 0.103 0.194 0.7112 1.14 0.934 1.4 -0.012 0.106 0.91 0.04099 0.988 0.803 1.22 PRS_PLINK_1e.04 415.1 Acute pulmonary heart disease Both 564 8245 8 circulatory system red 8245, 564 2062, 134 2061, 138 2061, 160 2061, 132 -0.0266 0.0435 0.54 0.2673 0.974 0.894 1.06 0.0331 0.125 0.791 0.102 1.03 0.81 1.32 0.173 0.121 0.153 0.816 1.19 0.938 1.51 -0.018 0.126 0.886 0.05238 0.982 0.768 1.26 PRS_PLINK_1e.04 415.11 Pulmonary embolism and infarction, acute Both 562 8206 8 circulatory system red 8206, 562 2052, 134 2051, 137 2051, 160 2052, 131 -0.0297 0.0435 0.495 0.3053 0.971 0.891 1.06 0.0266 0.125 0.831 0.0802 1.03 0.804 1.31 0.173 0.121 0.151 0.8197 1.19 0.939 1.51 -0.0231 0.126 0.855 0.06821 0.977 0.763 1.25 PRS_PLINK_1e.04 415.2 Chronic pulmonary heart disease Both 255 6810 8 circulatory system red 6810, 255 1703, 71 1702, 69 1702, 68 1703, 47 -0.122 0.0627 0.0528 1.277 0.886 0.783 1 -0.0183 0.17 0.914 0.03884 0.982 0.703 1.37 -0.0358 0.171 0.834 0.07892 0.965 0.69 1.35 -0.413 0.188 0.0283 1.549 0.662 0.457 0.957 PRS_PLINK_1e.04 415.21 Primary pulmonary hypertension Both 79 2727 8 circulatory system red 2727, 79 682, 23 682, 21 681, 17 682, 18 -0.105 0.109 0.337 0.4729 0.9 0.726 1.12 -0.102 0.292 0.727 0.1384 0.903 0.509 1.6 -0.278 0.309 0.368 0.4338 0.758 0.414 1.39 -0.213 0.305 0.485 0.3142 0.808 0.445 1.47 PRS_PLINK_1e.04 416 Cardiomegaly Both 209 4957 8 circulatory system red 4957, 209 1240, 52 1239, 53 1239, 55 1239, 49 -0.048 0.0687 0.485 0.3146 0.953 0.833 1.09 0.0545 0.196 0.781 0.1072 1.06 0.719 1.55 0.0602 0.194 0.756 0.1212 1.06 0.726 1.55 -0.0244 0.2 0.903 0.04454 0.976 0.66 1.44 PRS_PLINK_1e.04 418 Nonspecific chest pain Both 4366 19006 8 circulatory system red 19006, 4366 4752, 1105 4751, 1059 4751, 1118 4752, 1083 -0.00235 0.0169 0.889 0.05097 0.998 0.965 1.03 -0.0427 0.0479 0.373 0.4286 0.958 0.872 1.05 0.00521 0.0474 0.913 0.03974 1.01 0.916 1.1 -0.0254 0.0477 0.594 0.2261 0.975 0.888 1.07 PRS_PLINK_1e.04 418.1 Precordial pain Both 274 5931 8 circulatory system red 5931, 274 1483, 67 1483, 81 1482, 62 1483, 64 -0.0342 0.0612 0.576 0.2392 0.966 0.857 1.09 0.185 0.167 0.27 0.5678 1.2 0.866 1.67 -0.0679 0.177 0.701 0.1541 0.934 0.66 1.32 -0.0396 0.177 0.823 0.08485 0.961 0.68 1.36 PRS_PLINK_1e.04 420 Carditis Both 343 6271 8 circulatory system red 6271, 343 1568, 93 1568, 80 1567, 88 1568, 82 -0.0451 0.0545 0.408 0.3893 0.956 0.859 1.06 -0.147 0.155 0.342 0.4657 0.863 0.637 1.17 -0.028 0.152 0.854 0.06867 0.972 0.722 1.31 -0.107 0.155 0.487 0.3121 0.898 0.663 1.22 PRS_PLINK_1e.04 420.1 Myocarditis Both 26 419 8 circulatory system red 419, 26 105, 3 105, 9 104, 6 105, 8 0.177 0.201 0.378 0.4222 1.19 0.805 1.77 1.21 0.626 0.0537 1.27 3.35 0.981 11.4 0.602 0.611 0.325 0.4887 1.83 0.551 6.05 1 0.654 0.126 0.8984 2.72 0.754 9.81 PRS_PLINK_1e.04 420.2 Pericarditis Both 192 3499 8 circulatory system red 3499, 192 875, 55 875, 44 874, 47 875, 46 -0.0637 0.0723 0.378 0.4225 0.938 0.814 1.08 -0.235 0.204 0.249 0.6045 0.79 0.53 1.18 -0.139 0.201 0.49 0.3095 0.871 0.587 1.29 -0.159 0.202 0.43 0.3663 0.853 0.574 1.27 PRS_PLINK_1e.04 420.21 Acute pericarditis Both 48 792 8 circulatory system red 792, 48 198, 16 198, 14 198, 6 198, 12 -0.244 0.138 0.0767 1.115 0.784 0.598 1.03 -0.145 0.361 0.687 0.1629 0.865 0.426 1.76 -0.926 0.449 0.0392 1.406 0.396 0.164 0.955 -0.317 0.375 0.398 0.4004 0.728 0.349 1.52 PRS_PLINK_1e.04 420.22 Chronic pericarditis Both 24 517 8 circulatory system red 517, 24 130, 5 129, 9 129, 5 129, 5 -0.0556 0.189 0.769 0.1139 0.946 0.652 1.37 0.543 0.515 0.292 0.5343 1.72 0.627 4.72 0.0639 0.552 0.908 0.04202 1.07 0.362 3.14 0.00548 0.572 0.992 0.003337 1.01 0.328 3.08 PRS_PLINK_1e.04 420.3 Endocarditis Both 132 2825 8 circulatory system red 2825, 132 707, 35 706, 32 706, 34 706, 31 -0.058 0.0861 0.5 0.3008 0.944 0.797 1.12 -0.0725 0.244 0.766 0.1157 0.93 0.577 1.5 9.24e-05 0.241 1 0.0001331 1 0.624 1.6 -0.129 0.246 0.601 0.2212 0.879 0.542 1.42 PRS_PLINK_1e.04 425 Cardiomyopathy Both 330 7684 8 circulatory system red 7684, 330 1921, 91 1921, 80 1921, 81 1921, 78 -0.00138 0.0558 0.98 0.008622 0.999 0.895 1.11 -0.138 0.155 0.375 0.4257 0.871 0.643 1.18 -0.114 0.155 0.462 0.3349 0.893 0.659 1.21 -0.146 0.157 0.351 0.4548 0.864 0.636 1.17 PRS_PLINK_1e.04 425.1 Primary/intrinsic cardiomyopathies Both 311 7274 8 circulatory system red 7274, 311 1819, 83 1818, 78 1818, 77 1819, 73 0.00234 0.0575 0.968 0.01433 1 0.896 1.12 -0.067 0.16 0.675 0.1709 0.935 0.684 1.28 -0.0735 0.16 0.646 0.19 0.929 0.679 1.27 -0.116 0.163 0.475 0.3233 0.89 0.647 1.22 PRS_PLINK_1e.04 425.11 Hypertrophic obstructive cardiomyopathy Both 38 848 8 circulatory system red 848, 38 212, 9 212, 11 212, 10 212, 8 -0.142 0.153 0.355 0.45 0.868 0.643 1.17 0.143 0.429 0.739 0.1314 1.15 0.497 2.68 0.135 0.446 0.763 0.1177 1.14 0.477 2.74 -0.185 0.458 0.687 0.1631 0.831 0.339 2.04 PRS_PLINK_1e.04 425.12 Other hypertrophic cardiomyopathy Both 43 884 8 circulatory system red 884, 43 221, 16 221, 9 221, 12 221, 6 -0.302 0.145 0.0376 1.425 0.739 0.556 0.983 -0.524 0.407 0.198 0.7043 0.592 0.267 1.31 -0.282 0.384 0.463 0.3346 0.754 0.355 1.6 -0.923 0.457 0.0434 1.362 0.397 0.162 0.973 PRS_PLINK_1e.04 425.2 Secondary/extrinsic cardiomyopathies Both 63 1413 8 circulatory system red 1413, 63 354, 21 353, 16 353, 14 353, 12 -0.155 0.126 0.217 0.6632 0.856 0.669 1.1 -0.337 0.328 0.304 0.517 0.714 0.375 1.36 -0.409 0.341 0.23 0.6383 0.664 0.34 1.3 -0.569 0.358 0.112 0.9505 0.566 0.281 1.14 PRS_PLINK_1e.04 425.8 Other cardiomyopathy Both 8 391 8 circulatory system red 391, 8 98, 4 98, 0 97, 2 98, 2 -0.0677 0.288 0.814 0.08937 0.935 0.532 1.64 -1.92 1.23 0.119 0.9246 0.147 0.0131 1.64 -0.754 0.769 0.327 0.4861 0.47 0.104 2.12 -0.285 0.844 0.735 0.1334 0.752 0.144 3.93 PRS_PLINK_1e.04 426 Cardiac conduction disorders Both 3177 15885 8 circulatory system red 15885, 3177 3972, 759 3971, 831 3971, 825 3971, 761 -0.00631 0.02 0.752 0.1237 0.994 0.956 1.03 0.102 0.0567 0.0733 1.135 1.11 0.99 1.24 0.078 0.0568 0.17 0.7702 1.08 0.967 1.21 -0.00655 0.0574 0.909 0.04132 0.993 0.888 1.11 PRS_PLINK_1e.04 426.2 Atrioventricular [AV] block Both 263 5340 8 circulatory system red 5340, 263 1335, 59 1335, 67 1335, 86 1335, 51 0.00316 0.0617 0.959 0.01811 1 0.889 1.13 0.135 0.18 0.452 0.3453 1.15 0.805 1.63 0.39 0.172 0.0234 1.631 1.48 1.05 2.07 -0.129 0.192 0.501 0.3002 0.879 0.603 1.28 PRS_PLINK_1e.04 426.21 First degree AV block Both 163 3828 8 circulatory system red 3828, 163 957, 39 957, 44 957, 51 957, 29 -0.0557 0.0778 0.474 0.3247 0.946 0.812 1.1 0.123 0.219 0.574 0.2408 1.13 0.736 1.74 0.285 0.215 0.185 0.7323 1.33 0.872 2.03 -0.274 0.243 0.259 0.5863 0.76 0.472 1.22 PRS_PLINK_1e.04 426.22 Mobitz II AV block Both 8 214 8 circulatory system red 214, 8 54, 1 53, 2 53, 1 54, 4 0.21 0.339 0.536 0.2708 1.23 0.634 2.4 -0.243 0.869 0.779 0.1083 0.784 0.143 4.3 -0.21 0.914 0.818 0.08734 0.81 0.135 4.86 0.899 0.834 0.281 0.5512 2.46 0.479 12.6 PRS_PLINK_1e.04 426.23 Second degree AV block Both 27 777 8 circulatory system red 777, 27 195, 4 194, 9 194, 8 194, 6 0.197 0.185 0.287 0.542 1.22 0.847 1.75 0.833 0.539 0.123 0.9111 2.3 0.799 6.62 1.04 0.597 0.0814 1.089 2.83 0.878 9.11 0.373 0.559 0.505 0.2964 1.45 0.485 4.34 PRS_PLINK_1e.04 426.24 Atrioventricular block, complete Both 61 1595 8 circulatory system red 1595, 61 399, 12 399, 15 398, 21 399, 13 0.156 0.126 0.215 0.6676 1.17 0.913 1.5 0.375 0.375 0.317 0.499 1.45 0.698 3.03 0.673 0.356 0.0588 1.231 1.96 0.975 3.94 0.26 0.39 0.505 0.2968 1.3 0.604 2.79 PRS_PLINK_1e.04 426.25 Other heart block Both 33 730 8 circulatory system red 730, 33 183, 8 182, 6 182, 9 183, 10 0.152 0.17 0.371 0.4304 1.16 0.835 1.62 -0.117 0.519 0.822 0.08498 0.89 0.322 2.46 0.182 0.467 0.697 0.1569 1.2 0.48 2.99 0.358 0.466 0.442 0.3542 1.43 0.574 3.57 PRS_PLINK_1e.04 426.3 Bundle branch block Both 433 6861 8 circulatory system red 6861, 433 1716, 105 1715, 129 1715, 106 1715, 93 -0.0474 0.0487 0.33 0.4809 0.954 0.867 1.05 0.204 0.135 0.129 0.8889 1.23 0.942 1.6 0.00473 0.141 0.973 0.0118 1 0.763 1.32 -0.129 0.145 0.375 0.4262 0.879 0.661 1.17 PRS_PLINK_1e.04 426.31 Right bundle branch block Both 286 4964 8 circulatory system red 4964, 286 1241, 64 1241, 89 1241, 71 1241, 62 -0.0312 0.0595 0.6 0.222 0.969 0.863 1.09 0.33 0.166 0.0476 1.323 1.39 1 1.93 0.101 0.174 0.563 0.2495 1.11 0.786 1.56 -0.0324 0.18 0.857 0.06685 0.968 0.68 1.38 PRS_PLINK_1e.04 426.32 Left bundle branch block Both 142 3483 8 circulatory system red 3483, 142 871, 38 871, 38 870, 37 871, 29 -0.0737 0.0818 0.368 0.4344 0.929 0.791 1.09 0.0069 0.229 0.976 0.01055 1.01 0.642 1.58 0.00324 0.231 0.989 0.004901 1 0.638 1.58 -0.258 0.245 0.291 0.5354 0.773 0.478 1.25 PRS_PLINK_1e.04 426.4 Anomalous atrioventricular excitation Both 50 550 8 circulatory system red 550, 50 138, 10 137, 9 137, 15 138, 16 0.19 0.145 0.191 0.7197 1.21 0.91 1.61 -0.13 0.448 0.772 0.1124 0.878 0.365 2.11 0.55 0.416 0.186 0.7307 1.73 0.767 3.91 0.465 0.403 0.249 0.6033 1.59 0.722 3.51 PRS_PLINK_1e.04 426.7 Abnormal electrocardiogram [ECG] [EKG] Both 2666 15643 8 circulatory system red 15643, 2666 3911, 633 3911, 700 3910, 688 3911, 645 0.00137 0.0214 0.949 0.02263 1 0.96 1.04 0.108 0.0608 0.0755 1.122 1.11 0.989 1.25 0.0802 0.061 0.188 0.7248 1.08 0.961 1.22 0.00738 0.0616 0.905 0.04351 1.01 0.893 1.14 PRS_PLINK_1e.04 426.8 Other cardiac conduction disorders Both 119 3260 8 circulatory system red 3260, 119 815, 24 815, 37 815, 33 815, 24 -0.0532 0.0927 0.566 0.2474 0.948 0.791 1.14 0.453 0.259 0.0805 1.094 1.57 0.946 2.62 0.361 0.266 0.175 0.7567 1.43 0.852 2.42 0.0179 0.282 0.949 0.02258 1.02 0.586 1.77 PRS_PLINK_1e.04 426.9 Cardiac pacemaker/device in situ Both 295 5424 8 circulatory system red 5424, 295 1356, 66 1356, 77 1356, 79 1356, 73 0.0229 0.0589 0.698 0.1562 1.02 0.912 1.15 0.157 0.17 0.354 0.4514 1.17 0.839 1.63 0.189 0.169 0.263 0.5796 1.21 0.867 1.68 0.1 0.172 0.56 0.252 1.11 0.789 1.55 PRS_PLINK_1e.04 426.91 Cardiac pacemaker in situ Both 174 3532 8 circulatory system red 3532, 174 883, 35 883, 49 883, 46 883, 44 0.0434 0.0764 0.57 0.2441 1.04 0.899 1.21 0.335 0.221 0.13 0.8867 1.4 0.906 2.16 0.271 0.224 0.227 0.6443 1.31 0.845 2.03 0.222 0.227 0.326 0.4867 1.25 0.801 1.95 PRS_PLINK_1e.04 426.92 Cardiac defibrillator in situ Both 121 3198 8 circulatory system red 3198, 121 800, 32 799, 30 799, 34 800, 25 -0.0669 0.0898 0.456 0.3407 0.935 0.784 1.12 -0.0359 0.251 0.886 0.05244 0.965 0.59 1.58 0.0959 0.247 0.697 0.1565 1.1 0.679 1.79 -0.261 0.263 0.32 0.4944 0.77 0.46 1.29 PRS_PLINK_1e.04 427 Cardiac dysrhythmias Both 6054 16166 8 circulatory system red 16166, 6054 4042, 1527 4041, 1553 4041, 1545 4042, 1428 -0.0391 0.0152 0.0103 1.985 0.962 0.933 0.991 0.0183 0.0429 0.671 0.1734 1.02 0.936 1.11 0.00765 0.043 0.859 0.06614 1.01 0.926 1.1 -0.0765 0.0435 0.0788 1.104 0.926 0.851 1.01 PRS_PLINK_1e.04 427.1 Paroxysmal tachycardia, unspecified Both 643 9985 8 circulatory system red 9985, 643 2497, 181 2496, 156 2496, 155 2496, 151 -0.0516 0.0403 0.201 0.6977 0.95 0.878 1.03 -0.152 0.112 0.176 0.7552 0.859 0.689 1.07 -0.147 0.113 0.193 0.7146 0.864 0.693 1.08 -0.174 0.113 0.124 0.9061 0.84 0.673 1.05 PRS_PLINK_1e.04 427.11 Paroxysmal supraventricular tachycardia Both 482 7638 8 circulatory system red 7638, 482 1910, 130 1909, 120 1909, 114 1910, 118 -0.0306 0.0466 0.512 0.2908 0.97 0.885 1.06 -0.0957 0.13 0.462 0.3354 0.909 0.704 1.17 -0.133 0.132 0.312 0.5054 0.875 0.676 1.13 -0.0959 0.131 0.463 0.3342 0.909 0.703 1.17 PRS_PLINK_1e.04 427.12 Paroxysmal ventricular tachycardia Both 200 4636 8 circulatory system red 4636, 200 1159, 67 1159, 47 1159, 46 1159, 40 -0.195 0.0711 0.00617 2.21 0.823 0.716 0.946 -0.335 0.193 0.0817 1.088 0.715 0.49 1.04 -0.379 0.193 0.05 1.301 0.685 0.469 1 -0.523 0.201 0.00922 2.035 0.592 0.4 0.879 PRS_PLINK_1e.04 427.2 Atrial fibrillation and flutter Both 1018 10046 8 circulatory system red 10046, 1018 2512, 262 2511, 259 2511, 267 2512, 230 -0.0487 0.033 0.14 0.8534 0.952 0.893 1.02 0.00417 0.0941 0.965 0.01562 1 0.835 1.21 0.0267 0.093 0.774 0.1112 1.03 0.856 1.23 -0.122 0.0966 0.206 0.6864 0.885 0.732 1.07 PRS_PLINK_1e.04 427.21 Atrial fibrillation Both 984 9811 8 circulatory system red 9811, 984 2453, 256 2453, 255 2452, 255 2453, 218 -0.0541 0.0336 0.107 0.9699 0.947 0.887 1.01 0.0139 0.0949 0.884 0.05372 1.01 0.842 1.22 0.00625 0.0945 0.947 0.02355 1.01 0.836 1.21 -0.15 0.0983 0.128 0.8937 0.861 0.71 1.04 PRS_PLINK_1e.04 427.22 Atrial flutter Both 295 5017 8 circulatory system red 5017, 295 1255, 61 1254, 82 1254, 81 1254, 71 0.0612 0.059 0.3 0.5231 1.06 0.947 1.19 0.3 0.171 0.0801 1.097 1.35 0.965 1.89 0.296 0.172 0.0855 1.068 1.34 0.96 1.88 0.153 0.177 0.388 0.4112 1.17 0.824 1.65 PRS_PLINK_1e.04 427.3 Other specified cardiac dysrhythmias Both 2686 16001 8 circulatory system red 16001, 2686 4001, 682 4000, 686 4000, 668 4000, 650 -0.0297 0.021 0.157 0.8039 0.971 0.932 1.01 0.0167 0.0592 0.778 0.1089 1.02 0.905 1.14 -0.0204 0.0597 0.733 0.1351 0.98 0.872 1.1 -0.056 0.0599 0.35 0.4563 0.946 0.841 1.06 PRS_PLINK_1e.04 427.4 Cardiac arrest and ventricular fibrillation Both 94 2433 8 circulatory system red 2433, 94 609, 26 608, 29 608, 22 608, 17 -0.0931 0.102 0.359 0.4449 0.911 0.747 1.11 0.133 0.268 0.621 0.207 1.14 0.675 1.93 -0.156 0.289 0.589 0.2301 0.855 0.485 1.51 -0.396 0.306 0.195 0.7109 0.673 0.37 1.22 PRS_PLINK_1e.04 427.41 Ventricular fibrillation and flutter Both 35 979 8 circulatory system red 979, 35 245, 12 245, 11 244, 8 245, 4 -0.286 0.153 0.0615 1.211 0.751 0.557 1.01 0.027 0.408 0.947 0.02354 1.03 0.462 2.28 -0.483 0.438 0.27 0.569 0.617 0.262 1.45 -1.03 0.523 0.0494 1.306 0.358 0.129 0.998 PRS_PLINK_1e.04 427.42 Cardiac arrest Both 67 1869 8 circulatory system red 1869, 67 468, 18 467, 18 467, 18 467, 13 0.00979 0.123 0.937 0.0284 1.01 0.793 1.29 -0.00569 0.323 0.986 0.006145 0.994 0.528 1.87 0.0528 0.33 0.873 0.05901 1.05 0.552 2.01 -0.296 0.352 0.401 0.3968 0.744 0.373 1.48 PRS_PLINK_1e.04 427.5 Arrhythmia (cardiac) NOS Both 2093 15919 8 circulatory system red 15919, 2093 3980, 539 3980, 533 3979, 539 3980, 482 -0.0417 0.0233 0.073 1.136 0.959 0.916 1 -0.00599 0.0655 0.927 0.03284 0.994 0.874 1.13 -0.00209 0.0654 0.974 0.01122 0.998 0.878 1.13 -0.121 0.0669 0.071 1.149 0.886 0.777 1.01 PRS_PLINK_1e.04 427.6 Premature beats Both 559 8385 8 circulatory system red 8385, 559 2097, 140 2096, 146 2096, 141 2096, 132 -0.0466 0.0433 0.282 0.5501 0.954 0.877 1.04 0.0378 0.122 0.756 0.1215 1.04 0.818 1.32 0.00732 0.123 0.952 0.02119 1.01 0.792 1.28 -0.0631 0.124 0.612 0.2135 0.939 0.736 1.2 PRS_PLINK_1e.04 427.61 Supraventricular premature beats Both 141 2781 8 circulatory system red 2781, 141 696, 35 695, 32 695, 38 695, 36 0.042 0.0865 0.627 0.2026 1.04 0.88 1.24 -0.11 0.244 0.652 0.1856 0.896 0.555 1.45 0.076 0.234 0.746 0.1274 1.08 0.682 1.71 0.027 0.236 0.909 0.04143 1.03 0.646 1.63 PRS_PLINK_1e.04 427.7 Tachycardia NOS Both 1688 15983 8 circulatory system red 15983, 1688 3996, 442 3996, 408 3995, 427 3996, 410 -0.042 0.0254 0.0986 1.006 0.959 0.912 1.01 -0.0834 0.0722 0.248 0.6056 0.92 0.799 1.06 -0.0425 0.0714 0.552 0.2579 0.958 0.833 1.1 -0.0787 0.0721 0.275 0.5608 0.924 0.802 1.06 PRS_PLINK_1e.04 427.8 Sinoatrial node dysfunction (Bradycardia) Both 177 3271 8 circulatory system red 3271, 177 818, 34 818, 48 817, 46 818, 49 0.105 0.0761 0.167 0.7785 1.11 0.957 1.29 0.354 0.225 0.117 0.9335 1.42 0.916 2.22 0.341 0.227 0.132 0.8794 1.41 0.902 2.19 0.394 0.224 0.079 1.102 1.48 0.955 2.3 PRS_PLINK_1e.04 427.9 Palpitations Both 1659 15055 8 circulatory system red 15055, 1659 3764, 408 3764, 417 3763, 424 3764, 410 -0.012 0.026 0.645 0.1904 0.988 0.939 1.04 0.00985 0.0737 0.894 0.04886 1.01 0.874 1.17 0.0322 0.0734 0.661 0.1798 1.03 0.894 1.19 0.00158 0.074 0.983 0.007442 1 0.866 1.16 PRS_PLINK_1e.04 428 Congestive heart failure; nonhypertensive Both 556 11679 8 circulatory system red 11679, 556 2920, 135 2920, 149 2919, 149 2920, 123 0.0157 0.0431 0.716 0.145 1.02 0.934 1.11 0.0957 0.121 0.429 0.368 1.1 0.868 1.39 0.101 0.121 0.405 0.392 1.11 0.872 1.4 -0.0852 0.126 0.501 0.3004 0.918 0.717 1.18 PRS_PLINK_1e.04 428.1 Congestive heart failure (CHF) NOS Both 475 10814 8 circulatory system red 10814, 475 2704, 114 2703, 131 2703, 126 2704, 104 0.00849 0.0463 0.854 0.0683 1.01 0.921 1.1 0.134 0.13 0.304 0.5176 1.14 0.886 1.47 0.096 0.131 0.464 0.3336 1.1 0.851 1.42 -0.0863 0.137 0.528 0.277 0.917 0.701 1.2 PRS_PLINK_1e.04 428.2 Heart failure NOS Both 432 10372 8 circulatory system red 10372, 432 2593, 99 2593, 114 2593, 117 2593, 102 0.0624 0.0489 0.202 0.6957 1.06 0.967 1.17 0.137 0.139 0.324 0.4896 1.15 0.874 1.51 0.164 0.138 0.234 0.6299 1.18 0.899 1.55 0.0338 0.142 0.812 0.09036 1.03 0.783 1.37 PRS_PLINK_1e.04 428.3 Heart failure with reduced EF [Systolic or combined heart failure] Both 192 6241 8 circulatory system red 6241, 192 1561, 44 1560, 59 1560, 49 1560, 40 0.0291 0.072 0.687 0.1632 1.03 0.894 1.19 0.305 0.199 0.125 0.9029 1.36 0.919 2.01 0.135 0.207 0.513 0.2898 1.15 0.763 1.72 -0.0782 0.217 0.718 0.1439 0.925 0.605 1.41 PRS_PLINK_1e.04 428.4 Heart failure with preserved EF [Diastolic heart failure] Both 124 5587 8 circulatory system red 5587, 124 1397, 36 1397, 35 1396, 33 1397, 20 -0.106 0.0878 0.226 0.6467 0.899 0.757 1.07 -0.0237 0.234 0.919 0.03665 0.977 0.618 1.54 -0.0632 0.237 0.79 0.1024 0.939 0.59 1.49 -0.577 0.27 0.0324 1.489 0.562 0.331 0.953 PRS_PLINK_1e.04 429 Ill-defined descriptions and complications of heart disease Both 3960 19046 8 circulatory system red 19046, 3960 4762, 1001 4761, 1004 4761, 1010 4762, 944 -0.0219 0.0176 0.213 0.6724 0.978 0.945 1.01 0.00221 0.0496 0.965 0.01569 1 0.909 1.1 0.00361 0.0496 0.942 0.02601 1 0.911 1.11 -0.0694 0.0502 0.167 0.7774 0.933 0.845 1.03 PRS_PLINK_1e.04 429.1 Heart transplant/surgery Both 227 5129 8 circulatory system red 5129, 227 1283, 57 1282, 61 1282, 54 1282, 55 0.0132 0.0658 0.841 0.07528 1.01 0.891 1.15 0.0993 0.186 0.594 0.2262 1.1 0.766 1.59 -0.0399 0.191 0.834 0.07863 0.961 0.661 1.4 -0.028 0.19 0.883 0.05423 0.972 0.67 1.41 PRS_PLINK_1e.04 429.2 Abnormal function study of cardiovascular system Both 1322 16099 8 circulatory system red 16099, 1322 4025, 327 4025, 338 4024, 361 4025, 296 -0.0153 0.0287 0.594 0.2262 0.985 0.931 1.04 0.0344 0.0809 0.671 0.1734 1.03 0.883 1.21 0.0991 0.0799 0.215 0.6677 1.1 0.944 1.29 -0.107 0.0835 0.199 0.701 0.898 0.763 1.06 PRS_PLINK_1e.04 429.3 Symptoms involving cardiovascular system Both 3202 18970 8 circulatory system red 18970, 3202 4743, 813 4742, 814 4742, 799 4743, 775 -0.0267 0.0191 0.162 0.7901 0.974 0.938 1.01 -0.0018 0.0539 0.973 0.01172 0.998 0.898 1.11 -0.0214 0.0542 0.692 0.1598 0.979 0.88 1.09 -0.0565 0.0545 0.3 0.5232 0.945 0.849 1.05 PRS_PLINK_1e.04 429.9 Cardiac complications, not elsewhere classified Both 129 2897 8 circulatory system red 2897, 129 725, 29 724, 33 724, 30 724, 37 0.0533 0.0865 0.538 0.2692 1.05 0.89 1.25 0.131 0.253 0.604 0.2191 1.14 0.694 1.87 0.0671 0.258 0.795 0.09969 1.07 0.645 1.77 0.253 0.247 0.306 0.5137 1.29 0.793 2.09 PRS_PLINK_1e.04 430 Intracranial hemorrhage Both 205 3392 8 circulatory system red 3392, 205 848, 57 848, 60 848, 45 848, 43 -0.0801 0.0732 0.274 0.5622 0.923 0.8 1.07 0.0625 0.189 0.74 0.1305 1.06 0.735 1.54 -0.217 0.202 0.284 0.5464 0.805 0.542 1.2 -0.279 0.204 0.172 0.7651 0.756 0.507 1.13 PRS_PLINK_1e.04 430.1 Subarachnoid hemorrhage Both 61 1122 8 circulatory system red 1122, 61 281, 21 280, 18 280, 14 281, 8 -0.209 0.126 0.0965 1.016 0.811 0.634 1.04 -0.124 0.321 0.698 0.156 0.883 0.471 1.66 -0.367 0.34 0.281 0.5515 0.693 0.356 1.35 -0.903 0.399 0.0237 1.625 0.405 0.185 0.887 PRS_PLINK_1e.04 430.2 Intracerebral hemorrhage Both 88 1607 8 circulatory system red 1607, 88 402, 21 402, 31 401, 17 402, 19 -0.0803 0.111 0.467 0.3303 0.923 0.743 1.15 0.381 0.282 0.177 0.753 1.46 0.842 2.54 -0.277 0.326 0.396 0.4025 0.758 0.4 1.44 -0.0768 0.311 0.805 0.09415 0.926 0.503 1.7 PRS_PLINK_1e.04 430.3 Subdural hemorrhage Both 70 1066 8 circulatory system red 1066, 70 267, 17 266, 23 266, 16 267, 14 -0.0265 0.12 0.825 0.08329 0.974 0.769 1.23 0.372 0.324 0.251 0.6006 1.45 0.769 2.74 -0.0539 0.352 0.878 0.05632 0.948 0.475 1.89 -0.217 0.354 0.539 0.2683 0.805 0.402 1.61 PRS_PLINK_1e.04 433 Cerebrovascular disease Both 1127 14940 8 circulatory system red 14940, 1127 3735, 271 3735, 281 3735, 310 3735, 265 0.00504 0.0309 0.87 0.06024 1.01 0.946 1.07 0.0335 0.0881 0.704 0.1527 1.03 0.87 1.23 0.127 0.0863 0.14 0.8541 1.14 0.959 1.35 -0.028 0.0894 0.754 0.1227 0.972 0.816 1.16 PRS_PLINK_1e.04 433.1 Occlusion and stenosis of precerebral arteries Both 255 5779 8 circulatory system red 5779, 255 1445, 55 1445, 73 1444, 68 1445, 59 0.0297 0.0628 0.636 0.1965 1.03 0.911 1.17 0.289 0.18 0.108 0.9649 1.34 0.938 1.9 0.221 0.182 0.225 0.6474 1.25 0.873 1.78 0.0741 0.188 0.693 0.1592 1.08 0.745 1.56 PRS_PLINK_1e.04 433.11 Occlusion of cerebral arteries, with cerebral infarction Both 29 873 8 circulatory system red 873, 29 219, 6 218, 13 218, 7 218, 3 -0.232 0.179 0.195 0.7102 0.793 0.558 1.13 0.745 0.471 0.114 0.9425 2.11 0.836 5.31 0.17 0.508 0.738 0.1321 1.19 0.438 3.21 -0.513 0.591 0.386 0.4137 0.599 0.188 1.91 PRS_PLINK_1e.04 433.12 Cerebral atherosclerosis Both 7 256 8 circulatory system red 256, 7 64, 2 64, 2 64, 3 64, 0 -0.425 0.308 0.168 0.7755 0.654 0.357 1.2 -0.0575 0.758 0.939 0.02712 0.944 0.214 4.17 0.44 0.737 0.55 0.2596 1.55 0.367 6.58 -1.53 1.05 0.148 0.8311 0.217 0.0276 1.71 PRS_PLINK_1e.04 433.2 Occlusion of cerebral arteries Both 478 8788 8 circulatory system red 8788, 478 2197, 116 2197, 112 2197, 139 2197, 111 -0.00779 0.0468 0.868 0.06163 0.992 0.905 1.09 -0.0367 0.135 0.785 0.105 0.964 0.74 1.26 0.184 0.129 0.154 0.8137 1.2 0.934 1.55 -0.0313 0.135 0.817 0.08776 0.969 0.744 1.26 PRS_PLINK_1e.04 433.21 Cerebral artery occlusion, with cerebral infarction Both 453 8476 8 circulatory system red 8476, 453 2119, 111 2119, 104 2119, 135 2119, 103 -0.00528 0.0481 0.913 0.03972 0.995 0.905 1.09 -0.0672 0.139 0.628 0.2021 0.935 0.713 1.23 0.199 0.131 0.129 0.8885 1.22 0.944 1.58 -0.0631 0.139 0.65 0.1871 0.939 0.715 1.23 PRS_PLINK_1e.04 433.3 Cerebral ischemia Both 535 9237 8 circulatory system red 9237, 535 2310, 128 2309, 128 2309, 160 2309, 119 0.0135 0.0446 0.762 0.1182 1.01 0.929 1.11 -0.00819 0.128 0.949 0.02282 0.992 0.772 1.27 0.212 0.122 0.0818 1.087 1.24 0.974 1.57 -0.0732 0.13 0.573 0.2421 0.929 0.721 1.2 PRS_PLINK_1e.04 433.31 Transient cerebral ischemia Both 450 8189 8 circulatory system red 8189, 450 2048, 112 2047, 107 2047, 137 2047, 94 -0.00228 0.0483 0.962 0.01666 0.998 0.908 1.1 -0.0476 0.138 0.729 0.137 0.954 0.728 1.25 0.194 0.13 0.137 0.8636 1.21 0.94 1.57 -0.173 0.142 0.224 0.6502 0.841 0.637 1.11 PRS_PLINK_1e.04 433.5 Cerebral aneurysm Both 127 2135 8 circulatory system red 2135, 127 534, 42 534, 28 533, 28 534, 29 -0.127 0.091 0.164 0.7853 0.881 0.737 1.05 -0.414 0.246 0.0929 1.032 0.661 0.408 1.07 -0.4 0.247 0.105 0.9779 0.671 0.414 1.09 -0.335 0.245 0.172 0.7642 0.715 0.442 1.16 PRS_PLINK_1e.04 433.6 Acute, but ill-defined cerebrovascular disease Both 55 1625 8 circulatory system red 1625, 55 407, 11 406, 14 406, 12 406, 18 0.195 0.137 0.154 0.813 1.22 0.929 1.59 0.218 0.378 0.565 0.248 1.24 0.592 2.61 0.0409 0.393 0.917 0.03764 1.04 0.482 2.25 0.492 0.364 0.177 0.7528 1.64 0.801 3.34 PRS_PLINK_1e.04 433.8 Late effects of cerebrovascular disease Both 124 2711 8 circulatory system red 2711, 124 678, 37 678, 30 677, 29 678, 28 -0.00931 0.0916 0.919 0.03668 0.991 0.828 1.19 -0.168 0.245 0.491 0.3086 0.845 0.523 1.37 -0.229 0.247 0.354 0.451 0.795 0.49 1.29 -0.237 0.25 0.343 0.4643 0.789 0.483 1.29 PRS_PLINK_1e.04 440 Atherosclerosis Both 298 7947 8 circulatory system red 7947, 298 1987, 70 1987, 76 1986, 83 1987, 69 0.0351 0.0587 0.55 0.2595 1.04 0.923 1.16 0.0604 0.167 0.717 0.1442 1.06 0.766 1.47 0.172 0.163 0.293 0.5334 1.19 0.862 1.64 -0.0148 0.17 0.93 0.0313 0.985 0.706 1.37 PRS_PLINK_1e.04 440.1 Atherosclerosis of renal artery Both 11 848 8 circulatory system red 848, 11 212, 3 212, 0 212, 4 212, 4 0.197 0.264 0.456 0.3415 1.22 0.726 2.04 -1.81 1.04 0.082 1.086 0.164 0.0214 1.26 0.0683 0.651 0.916 0.03788 1.07 0.299 3.84 0.305 0.618 0.622 0.206 1.36 0.404 4.55 PRS_PLINK_1e.04 440.2 Atherosclerosis of the extremities Both 179 5179 8 circulatory system red 5179, 179 1295, 37 1295, 47 1294, 49 1295, 46 0.0784 0.0764 0.305 0.5162 1.08 0.931 1.26 0.223 0.218 0.308 0.5112 1.25 0.814 1.92 0.265 0.217 0.223 0.6522 1.3 0.851 1.99 0.206 0.219 0.346 0.4611 1.23 0.8 1.89 PRS_PLINK_1e.04 440.21 Atherosclerosis of native arteries of the extremities with ulceration or gangrene Both 14 895 8 circulatory system red 895, 14 224, 2 224, 4 223, 3 224, 5 0.19 0.251 0.449 0.348 1.21 0.74 1.98 0.5 0.66 0.448 0.3483 1.65 0.452 6.01 0.162 0.724 0.823 0.08463 1.18 0.285 4.86 1.07 0.686 0.117 0.9314 2.93 0.764 11.2 PRS_PLINK_1e.04 440.22 Atherosclerosis of native arteries of the extremities with intermittent claudication Both 121 3481 8 circulatory system red 3481, 121 871, 28 870, 33 870, 33 870, 27 0.0212 0.091 0.816 0.08856 1.02 0.855 1.22 0.174 0.255 0.495 0.3058 1.19 0.722 1.96 0.152 0.254 0.551 0.2589 1.16 0.707 1.92 -0.0546 0.265 0.837 0.07753 0.947 0.564 1.59 PRS_PLINK_1e.04 440.9 Atherosclerosis of aorta Both 77 2798 8 circulatory system red 2798, 77 700, 18 699, 25 699, 18 700, 16 -0.0239 0.111 0.829 0.08162 0.976 0.786 1.21 0.294 0.3 0.327 0.4849 1.34 0.745 2.42 0.0439 0.321 0.891 0.04993 1.04 0.556 1.96 -0.118 0.328 0.719 0.1432 0.889 0.467 1.69 PRS_PLINK_1e.04 441 Vascular insufficiency of intestine Both 138 2118 8 circulatory system red 2118, 138 530, 32 529, 34 529, 30 530, 42 0.0974 0.0859 0.257 0.5909 1.1 0.932 1.3 0.0547 0.248 0.825 0.08338 1.06 0.65 1.72 -0.0218 0.256 0.932 0.03056 0.978 0.593 1.62 0.268 0.237 0.259 0.5875 1.31 0.821 2.08 PRS_PLINK_1e.04 441.1 Acute vascular insufficiency of intestine Both 64 1007 8 circulatory system red 1007, 64 252, 19 252, 16 251, 12 252, 17 -0.0528 0.125 0.673 0.1718 0.949 0.742 1.21 -0.0977 0.336 0.771 0.1129 0.907 0.47 1.75 -0.352 0.366 0.336 0.4742 0.703 0.343 1.44 -0.108 0.332 0.745 0.1281 0.898 0.469 1.72 PRS_PLINK_1e.04 441.2 Chronic vascular insufficiency of intestine Both 31 599 8 circulatory system red 599, 31 150, 6 150, 6 149, 8 150, 11 0.326 0.18 0.0711 1.148 1.38 0.972 1.97 0.116 0.519 0.824 0.08432 1.12 0.406 3.11 0.287 0.504 0.569 0.2448 1.33 0.496 3.58 0.615 0.479 0.199 0.7012 1.85 0.724 4.73 PRS_PLINK_1e.04 442 Other aneurysm Both 490 9117 8 circulatory system red 9117, 490 2280, 134 2279, 135 2279, 109 2279, 112 -0.0512 0.0459 0.265 0.5771 0.95 0.868 1.04 -0.000529 0.125 0.997 0.001474 0.999 0.783 1.28 -0.203 0.131 0.122 0.9126 0.816 0.631 1.06 -0.178 0.13 0.171 0.7668 0.837 0.648 1.08 PRS_PLINK_1e.04 442.1 Aortic aneurysm Both 308 6476 8 circulatory system red 6476, 308 1619, 79 1619, 84 1619, 70 1619, 75 -0.0134 0.0572 0.814 0.08919 0.987 0.882 1.1 0.0627 0.159 0.693 0.1591 1.06 0.78 1.45 -0.11 0.166 0.507 0.2949 0.896 0.647 1.24 -0.0513 0.163 0.753 0.1234 0.95 0.69 1.31 PRS_PLINK_1e.04 442.11 Abdominal aortic aneurysm Both 155 3705 8 circulatory system red 3705, 155 927, 40 926, 40 926, 35 926, 40 0.0134 0.079 0.865 0.06303 1.01 0.868 1.18 -0.00704 0.224 0.975 0.01104 0.993 0.641 1.54 -0.128 0.231 0.58 0.2363 0.88 0.56 1.38 0.00319 0.222 0.989 0.004992 1 0.649 1.55 PRS_PLINK_1e.04 442.2 Aneurysm of iliac artery Both 25 645 8 circulatory system red 645, 25 162, 9 161, 5 161, 7 161, 4 -0.322 0.18 0.0738 1.132 0.725 0.509 1.03 -0.629 0.514 0.221 0.6553 0.533 0.195 1.46 -0.34 0.477 0.476 0.3222 0.712 0.279 1.81 -0.75 0.538 0.163 0.7878 0.472 0.164 1.36 PRS_PLINK_1e.04 442.3 Aneurysm of artery of lower extremity Both 28 659 8 circulatory system red 659, 28 165, 7 165, 8 164, 5 165, 8 -0.0976 0.18 0.587 0.2314 0.907 0.638 1.29 0.2 0.493 0.684 0.1649 1.22 0.465 3.21 -0.388 0.533 0.467 0.3307 0.678 0.238 1.93 -0.0148 0.492 0.976 0.01054 0.985 0.376 2.58 PRS_PLINK_1e.04 442.4 Arterial dissection Both 31 782 8 circulatory system red 782, 31 196, 9 195, 10 195, 5 196, 7 -0.105 0.181 0.56 0.2519 0.9 0.631 1.28 0.0946 0.453 0.835 0.07843 1.1 0.452 2.67 -0.648 0.518 0.211 0.6766 0.523 0.19 1.44 -0.24 0.473 0.611 0.2137 0.787 0.311 1.99 PRS_PLINK_1e.04 442.8 Aneurysm of other specified artery Both 81 1708 8 circulatory system red 1708, 81 427, 22 427, 26 427, 11 427, 22 -0.122 0.106 0.252 0.5981 0.886 0.719 1.09 0.174 0.289 0.547 0.2618 1.19 0.675 2.1 -0.705 0.358 0.0488 1.312 0.494 0.245 0.996 -0.00749 0.297 0.98 0.008826 0.993 0.554 1.78 PRS_PLINK_1e.04 443 Peripheral vascular disease Both 626 11113 8 circulatory system red 11113, 626 2779, 149 2778, 155 2778, 150 2778, 172 0.0418 0.0412 0.31 0.5083 1.04 0.962 1.13 0.0403 0.117 0.731 0.1362 1.04 0.827 1.31 0.00999 0.118 0.933 0.03027 1.01 0.801 1.27 0.14 0.115 0.222 0.6534 1.15 0.919 1.44 PRS_PLINK_1e.04 443.1 Raynaud's syndrome Both 348 3932 8 circulatory system red 3932, 348 983, 74 983, 84 983, 87 983, 103 0.131 0.0576 0.023 1.639 1.14 1.02 1.28 0.127 0.164 0.439 0.3578 1.14 0.823 1.57 0.159 0.163 0.33 0.4818 1.17 0.852 1.61 0.328 0.158 0.0372 1.429 1.39 1.02 1.89 PRS_PLINK_1e.04 443.7 Peripheral angiopathy in diseases classified elsewhere Both 8 669 8 circulatory system red 669, 8 168, 2 167, 2 167, 1 167, 3 0.0985 0.293 0.737 0.1325 1.1 0.621 1.96 0.0646 0.731 0.93 0.03173 1.07 0.255 4.47 -0.828 0.844 0.326 0.4864 0.437 0.0835 2.28 0.267 0.683 0.696 0.1575 1.31 0.342 4.98 PRS_PLINK_1e.04 443.8 Other specified peripheral vascular diseases Both 532 9500 8 circulatory system red 9500, 532 2375, 122 2375, 131 2375, 125 2375, 154 0.0721 0.0446 0.106 0.9749 1.07 0.985 1.17 0.0708 0.128 0.581 0.2356 1.07 0.835 1.38 0.0275 0.13 0.832 0.07976 1.03 0.797 1.33 0.23 0.124 0.0634 1.198 1.26 0.987 1.61 PRS_PLINK_1e.04 443.9 Peripheral vascular disease, unspecified Both 288 7457 8 circulatory system red 7457, 288 1865, 75 1864, 75 1864, 62 1864, 76 -0.047 0.0589 0.425 0.3717 0.954 0.85 1.07 0.00334 0.164 0.984 0.007102 1 0.727 1.38 -0.199 0.173 0.248 0.6053 0.819 0.584 1.15 0.0218 0.164 0.894 0.0485 1.02 0.741 1.41 PRS_PLINK_1e.04 444 Arterial embolism and thrombosis Both 167 3608 8 circulatory system red 3608, 167 902, 51 902, 40 902, 40 902, 36 -0.0971 0.0773 0.209 0.68 0.907 0.78 1.06 -0.28 0.214 0.192 0.7174 0.756 0.497 1.15 -0.255 0.213 0.232 0.6354 0.775 0.51 1.18 -0.376 0.219 0.0868 1.062 0.687 0.447 1.06 PRS_PLINK_1e.04 444.1 Arterial embolism and thrombosis of lower extremity artery Both 48 1164 8 circulatory system red 1164, 48 291, 16 291, 8 291, 10 291, 14 -0.0518 0.142 0.716 0.1453 0.949 0.718 1.25 -0.859 0.433 0.0474 1.324 0.424 0.181 0.99 -0.489 0.393 0.213 0.6712 0.613 0.284 1.32 -0.206 0.364 0.571 0.2432 0.814 0.399 1.66 PRS_PLINK_1e.04 444.2 Embolism and thrombosis of abdominal aorta Both 11 577 8 circulatory system red 577, 11 145, 4 144, 2 144, 3 144, 2 -0.0689 0.267 0.796 0.09896 0.933 0.553 1.57 -0.553 0.678 0.415 0.3823 0.575 0.152 2.17 -0.153 0.637 0.81 0.09131 0.858 0.246 2.99 -0.321 0.702 0.648 0.1886 0.726 0.183 2.87 PRS_PLINK_1e.04 446 Polyarteritis nodosa and allied conditions Both 117 2034 8 circulatory system red 2034, 117 509, 27 508, 36 508, 32 509, 22 -0.0413 0.0915 0.652 0.1858 0.96 0.802 1.15 0.276 0.255 0.278 0.5555 1.32 0.8 2.17 0.172 0.262 0.511 0.2918 1.19 0.711 1.98 -0.247 0.283 0.383 0.4174 0.781 0.448 1.36 PRS_PLINK_1e.04 446.4 Wegener's granulomatosis Both 34 511 8 circulatory system red 511, 34 128, 7 128, 12 127, 9 128, 6 -0.0503 0.167 0.764 0.1172 0.951 0.685 1.32 0.536 0.465 0.25 0.6029 1.71 0.687 4.25 0.181 0.486 0.709 0.1492 1.2 0.462 3.11 -0.229 0.527 0.663 0.1783 0.795 0.283 2.23 PRS_PLINK_1e.04 446.5 Giant cell arteritis Both 14 234 8 circulatory system red 234, 14 59, 5 58, 4 58, 3 59, 2 -0.251 0.271 0.354 0.4507 0.778 0.457 1.32 -0.189 0.63 0.764 0.1166 0.828 0.241 2.84 -0.488 0.659 0.459 0.3378 0.614 0.169 2.24 -0.809 0.72 0.261 0.5838 0.445 0.109 1.82 PRS_PLINK_1e.04 446.9 Arteritis NOS Both 69 1321 8 circulatory system red 1321, 69 331, 16 330, 18 330, 25 330, 10 -0.04 0.12 0.739 0.1315 0.961 0.76 1.22 0.0663 0.336 0.843 0.074 1.07 0.554 2.06 0.401 0.316 0.205 0.6886 1.49 0.804 2.77 -0.481 0.383 0.209 0.6792 0.618 0.291 1.31 PRS_PLINK_1e.04 447 Other disorders of arteries and arterioles Both 491 10029 8 circulatory system red 10029, 491 2508, 135 2507, 132 2507, 118 2507, 105 -0.111 0.0456 0.0151 1.821 0.895 0.818 0.979 -0.0346 0.125 0.782 0.1069 0.966 0.756 1.23 -0.14 0.129 0.277 0.5574 0.87 0.676 1.12 -0.25 0.132 0.0588 1.231 0.779 0.601 1.01 PRS_PLINK_1e.04 447.1 Stricture of artery Both 73 2083 8 circulatory system red 2083, 73 521, 24 521, 22 520, 19 521, 8 -0.236 0.113 0.0361 1.443 0.789 0.633 0.985 -0.174 0.294 0.553 0.2572 0.84 0.473 1.49 -0.34 0.305 0.265 0.5768 0.712 0.391 1.29 -1.19 0.391 0.0024 2.62 0.305 0.142 0.657 PRS_PLINK_1e.04 447.7 Aortic ectasia Both 144 3103 8 circulatory system red 3103, 144 776, 38 776, 36 775, 33 776, 37 -0.0328 0.0845 0.698 0.1559 0.968 0.82 1.14 -0.0593 0.233 0.799 0.09755 0.942 0.597 1.49 -0.12 0.237 0.613 0.2124 0.887 0.557 1.41 -0.00176 0.233 0.994 0.002624 0.998 0.633 1.57 PRS_PLINK_1e.04 448 Disease of capillaries Both 542 5336 8 circulatory system red 5336, 542 1334, 126 1334, 140 1334, 134 1334, 142 0.038 0.0446 0.395 0.4035 1.04 0.952 1.13 0.0989 0.128 0.441 0.3558 1.1 0.859 1.42 0.0502 0.129 0.698 0.1561 1.05 0.816 1.35 0.113 0.128 0.375 0.4264 1.12 0.872 1.44 PRS_PLINK_1e.04 450 Noninfectious disorders of lymphatic channels Both 812 9316 8 circulatory system red 9316, 812 2329, 188 2329, 195 2329, 192 2329, 237 0.0514 0.0371 0.166 0.7803 1.05 0.979 1.13 0.0354 0.106 0.738 0.1318 1.04 0.842 1.28 0.0233 0.106 0.827 0.08261 1.02 0.831 1.26 0.233 0.102 0.022 1.657 1.26 1.03 1.54 PRS_PLINK_1e.04 451 Phlebitis and thrombophlebitis Both 263 3595 8 circulatory system red 3595, 263 899, 62 899, 67 898, 74 899, 60 0.00442 0.0648 0.946 0.02433 1 0.885 1.14 0.06 0.18 0.739 0.1313 1.06 0.746 1.51 0.17 0.176 0.336 0.474 1.18 0.839 1.67 -0.0543 0.185 0.769 0.1141 0.947 0.659 1.36 PRS_PLINK_1e.04 451.2 Phlebitis and thrombophlebitis of lower extremities Both 95 1202 8 circulatory system red 1202, 95 301, 22 300, 23 300, 26 301, 24 0.035 0.106 0.742 0.1297 1.04 0.841 1.28 0.05 0.298 0.867 0.0621 1.05 0.586 1.88 0.172 0.292 0.555 0.2558 1.19 0.671 2.1 0.046 0.297 0.877 0.05712 1.05 0.585 1.87 PRS_PLINK_1e.04 452 Other venous embolism and thrombosis Both 1592 16025 8 circulatory system red 16025, 1592 4007, 376 4006, 420 4006, 408 4006, 387 -0.00772 0.0264 0.77 0.1136 0.992 0.942 1.04 0.109 0.0745 0.144 0.8413 1.12 0.963 1.29 0.0765 0.0751 0.309 0.5106 1.08 0.932 1.25 0.015 0.076 0.844 0.07385 1.02 0.875 1.18 PRS_PLINK_1e.04 452.1 Iatrogenic pulmonary embolism and infarction Both 80 1310 8 circulatory system red 1310, 80 328, 14 327, 26 327, 19 328, 21 0.106 0.118 0.368 0.4336 1.11 0.882 1.4 0.644 0.327 0.0489 1.311 1.9 1 3.61 0.242 0.347 0.486 0.3137 1.27 0.645 2.51 0.373 0.338 0.27 0.5685 1.45 0.748 2.82 PRS_PLINK_1e.04 452.2 Deep vein thrombosis [DVT] Both 1079 13613 8 circulatory system red 13613, 1079 3404, 243 3403, 271 3403, 290 3403, 274 0.0237 0.0317 0.455 0.3416 1.02 0.962 1.09 0.11 0.0913 0.227 0.6438 1.12 0.934 1.34 0.177 0.0901 0.0496 1.304 1.19 1 1.42 0.111 0.0911 0.224 0.6498 1.12 0.934 1.34 PRS_PLINK_1e.04 452.8 Postphlebitic syndrome Both 74 864 8 circulatory system red 864, 74 216, 15 216, 21 216, 17 216, 20 -0.0185 0.117 0.875 0.05815 0.982 0.781 1.23 0.359 0.341 0.293 0.5335 1.43 0.734 2.79 0.0856 0.354 0.809 0.09218 1.09 0.545 2.18 0.24 0.343 0.484 0.3154 1.27 0.649 2.49 PRS_PLINK_1e.04 453 Chronic venous hypertension Both 86 1055 8 circulatory system red 1055, 86 264, 18 264, 24 263, 24 264, 20 -0.0265 0.113 0.814 0.08937 0.974 0.781 1.21 0.294 0.316 0.352 0.4539 1.34 0.723 2.49 0.308 0.319 0.335 0.4746 1.36 0.727 2.54 -0.0197 0.326 0.952 0.02141 0.981 0.517 1.86 PRS_PLINK_1e.04 454 Varicose veins Both 1154 12453 8 circulatory system red 12453, 1154 3114, 279 3113, 309 3113, 277 3113, 289 0.00378 0.0309 0.903 0.04444 1 0.945 1.07 0.106 0.0862 0.219 0.6594 1.11 0.939 1.32 -0.00812 0.0884 0.927 0.03299 0.992 0.834 1.18 0.0307 0.0875 0.726 0.1391 1.03 0.869 1.22 PRS_PLINK_1e.04 454.1 Varicose veins of lower extremity Both 948 10389 8 circulatory system red 10389, 948 2598, 227 2597, 245 2597, 236 2597, 240 0.0209 0.0342 0.541 0.2664 1.02 0.955 1.09 0.0847 0.096 0.378 0.4229 1.09 0.902 1.31 0.0393 0.0968 0.685 0.1644 1.04 0.86 1.26 0.0518 0.0965 0.591 0.2282 1.05 0.872 1.27 PRS_PLINK_1e.04 454.11 Varicose veins of lower extremity, symptomtic Both 588 6991 8 circulatory system red 6991, 588 1748, 141 1748, 153 1747, 137 1748, 157 0.0133 0.0434 0.76 0.1194 1.01 0.931 1.1 0.0867 0.121 0.475 0.3238 1.09 0.86 1.38 -0.0249 0.124 0.841 0.07544 0.975 0.765 1.24 0.101 0.12 0.403 0.3943 1.11 0.873 1.4 PRS_PLINK_1e.04 455 Hemorrhoids Both 2176 15926 8 circulatory system red 15926, 2176 3982, 552 3981, 551 3981, 550 3982, 523 -0.038 0.023 0.0984 1.007 0.963 0.92 1.01 -0.00555 0.0648 0.932 0.03068 0.994 0.876 1.13 -0.0043 0.065 0.947 0.02355 0.996 0.877 1.13 -0.057 0.0656 0.385 0.4141 0.945 0.831 1.07 PRS_PLINK_1e.04 456 Chronic venous insufficiency [CVI] Both 1018 12425 8 circulatory system red 12425, 1018 3107, 267 3106, 267 3106, 238 3106, 246 -0.0395 0.0327 0.227 0.6435 0.961 0.902 1.02 0.000698 0.0901 0.994 0.002691 1 0.839 1.19 -0.122 0.0926 0.189 0.7238 0.885 0.739 1.06 -0.0879 0.0918 0.338 0.4705 0.916 0.765 1.1 PRS_PLINK_1e.04 457 Encounter for long-term (current) use of anticoagulants, antithrombotics, aspirin Both 297 6267 8 circulatory system red 6267, 297 1567, 90 1567, 87 1566, 61 1567, 59 -0.138 0.0577 0.0169 1.773 0.871 0.778 0.976 -0.0294 0.153 0.848 0.07172 0.971 0.719 1.31 -0.384 0.168 0.0222 1.653 0.681 0.49 0.947 -0.406 0.169 0.0165 1.782 0.666 0.478 0.929 PRS_PLINK_1e.04 457.2 Encounter for long-term (current) use of antiplatelets/antithrombotics Both 36 1136 8 circulatory system red 1136, 36 284, 11 284, 12 284, 6 284, 7 -0.178 0.162 0.272 0.5647 0.837 0.609 1.15 0.131 0.4 0.743 0.1293 1.14 0.521 2.5 -0.569 0.475 0.231 0.6368 0.566 0.223 1.44 -0.412 0.445 0.355 0.4502 0.662 0.277 1.58 PRS_PLINK_1e.04 457.3 Encounter for long-term (current) use of aspirin Both 277 6000 8 circulatory system red 6000, 277 1500, 83 1500, 82 1500, 57 1500, 55 -0.131 0.0597 0.0278 1.556 0.877 0.78 0.986 -0.00652 0.158 0.967 0.01451 0.994 0.729 1.35 -0.372 0.174 0.0321 1.493 0.689 0.491 0.969 -0.39 0.176 0.0261 1.583 0.677 0.48 0.955 PRS_PLINK_1e.04 458 Hypotension Both 1252 17078 8 circulatory system red 17078, 1252 4270, 297 4269, 311 4269, 348 4270, 296 0.015 0.0294 0.609 0.2154 1.02 0.958 1.08 0.0464 0.0839 0.58 0.2363 1.05 0.889 1.23 0.154 0.0819 0.0598 1.224 1.17 0.994 1.37 -0.00232 0.0849 0.978 0.009577 0.998 0.845 1.18 PRS_PLINK_1e.04 458.1 Orthostatic hypotension Both 330 5851 8 circulatory system red 5851, 330 1463, 78 1463, 79 1462, 94 1463, 79 0.00895 0.0568 0.875 0.05813 1.01 0.903 1.13 0.0353 0.162 0.828 0.082 1.04 0.754 1.42 0.193 0.157 0.217 0.6639 1.21 0.893 1.65 0.0221 0.163 0.892 0.04953 1.02 0.743 1.41 PRS_PLINK_1e.04 458.2 Iatrogenic hypotension Both 210 4589 8 circulatory system red 4589, 210 1148, 47 1147, 57 1147, 62 1147, 44 0.0364 0.0711 0.609 0.2155 1.04 0.902 1.19 0.175 0.198 0.375 0.4256 1.19 0.809 1.76 0.301 0.196 0.123 0.9088 1.35 0.921 1.98 -0.0685 0.21 0.744 0.1282 0.934 0.619 1.41 PRS_PLINK_1e.04 458.9 Hypotension NOS Both 1132 16280 8 circulatory system red 16280, 1132 4070, 267 4070, 288 4070, 309 4070, 268 0.0142 0.0308 0.645 0.1906 1.01 0.955 1.08 0.074 0.0876 0.399 0.3994 1.08 0.907 1.28 0.14 0.0863 0.105 0.9792 1.15 0.971 1.36 0.00542 0.0891 0.951 0.02161 1.01 0.844 1.2 PRS_PLINK_1e.04 459 Other disorders of circulatory system Both 2086 19297 8 circulatory system red 19297, 2086 4825, 527 4824, 489 4824, 543 4824, 526 -0.0127 0.0231 0.582 0.2353 0.987 0.944 1.03 -0.0688 0.0662 0.299 0.5243 0.934 0.82 1.06 0.0312 0.0648 0.63 0.2006 1.03 0.909 1.17 -0.00576 0.0652 0.93 0.03169 0.994 0.875 1.13 PRS_PLINK_1e.04 459.1 Hemorrhage NOS Both 237 3829 8 circulatory system red 3829, 237 958, 69 957, 46 957, 56 957, 66 -0.0663 0.0659 0.314 0.5026 0.936 0.822 1.06 -0.407 0.193 0.0346 1.46 0.666 0.456 0.971 -0.19 0.184 0.301 0.5215 0.827 0.577 1.19 -0.0496 0.177 0.779 0.1087 0.952 0.673 1.34 PRS_PLINK_1e.04 459.7 Blood vessel replaced Both 363 6037 8 circulatory system red 6037, 363 1510, 87 1509, 86 1509, 92 1509, 98 0.0254 0.0538 0.636 0.1963 1.03 0.923 1.14 -0.0137 0.155 0.93 0.03155 0.986 0.728 1.34 0.065 0.153 0.671 0.1734 1.07 0.791 1.44 0.12 0.151 0.425 0.3716 1.13 0.839 1.52 PRS_PLINK_1e.04 459.9 Circulatory disease NEC Both 1658 18242 8 circulatory system red 18242, 1658 4561, 419 4560, 399 4560, 427 4561, 412 -0.0159 0.0257 0.535 0.2717 0.984 0.936 1.03 -0.0404 0.0731 0.58 0.2363 0.96 0.832 1.11 0.0221 0.0721 0.759 0.1197 1.02 0.888 1.18 -0.0188 0.0728 0.796 0.09884 0.981 0.851 1.13 PRS_PLINK_1e.04 464 Acute sinusitis Both 2127 16706 9 respiratory coral4 16706, 2127 4177, 511 4176, 500 4176, 585 4177, 531 0.0388 0.0233 0.0958 1.019 1.04 0.993 1.09 -0.0189 0.067 0.778 0.1091 0.981 0.86 1.12 0.136 0.0648 0.0352 1.453 1.15 1.01 1.3 0.036 0.0661 0.586 0.2322 1.04 0.911 1.18 PRS_PLINK_1e.04 465 Acute upper respiratory infections of multiple or unspecified sites Both 4549 18333 9 respiratory coral4 18333, 4549 4584, 1098 4583, 1100 4583, 1181 4583, 1169 0.028 0.0169 0.0965 1.016 1.03 0.995 1.06 -8.86e-05 0.0483 0.999 0.0006363 1 0.91 1.1 0.0755 0.0477 0.113 0.946 1.08 0.982 1.18 0.0717 0.0477 0.133 0.8773 1.07 0.978 1.18 PRS_PLINK_1e.04 465.2 Acute pharyngitis Both 2878 17348 9 respiratory coral4 17348, 2878 4337, 677 4337, 702 4337, 753 4337, 746 0.0337 0.0205 0.101 0.9975 1.03 0.994 1.08 0.0364 0.0589 0.537 0.2699 1.04 0.924 1.16 0.109 0.0582 0.06 1.222 1.12 0.995 1.25 0.112 0.0582 0.0552 1.258 1.12 0.997 1.25 PRS_PLINK_1e.04 465.4 Acute laryngitis and tracheitis Both 180 2277 9 respiratory coral4 2277, 180 570, 33 569, 36 569, 61 569, 50 0.132 0.0775 0.0886 1.053 1.14 0.98 1.33 0.0849 0.241 0.725 0.1397 1.09 0.678 1.75 0.616 0.22 0.00502 2.3 1.85 1.2 2.85 0.403 0.228 0.0772 1.112 1.5 0.957 2.34 PRS_PLINK_1e.04 470 Septal Deviations/Turbinate Hypertrophy Both 970 9935 9 respiratory coral4 9935, 970 2484, 224 2484, 232 2483, 241 2484, 273 0.0384 0.0335 0.251 0.6003 1.04 0.973 1.11 0.035 0.0976 0.72 0.1428 1.04 0.855 1.25 0.073 0.0967 0.45 0.3465 1.08 0.89 1.3 0.202 0.0943 0.0325 1.488 1.22 1.02 1.47 PRS_PLINK_1e.04 471 Nasal polyps Both 284 3051 9 respiratory coral4 3051, 284 763, 52 763, 86 762, 70 763, 76 0.0617 0.0623 0.322 0.4921 1.06 0.941 1.2 0.497 0.181 0.00617 2.21 1.64 1.15 2.34 0.308 0.188 0.101 0.9965 1.36 0.942 1.97 0.374 0.185 0.0431 1.366 1.45 1.01 2.09 PRS_PLINK_1e.04 472 Chronic pharyngitis and nasopharyngitis Both 740 8684 9 respiratory coral4 8684, 740 2171, 159 2171, 194 2171, 188 2171, 199 0.0547 0.0386 0.157 0.8047 1.06 0.979 1.14 0.197 0.111 0.0754 1.123 1.22 0.98 1.51 0.169 0.112 0.13 0.8877 1.18 0.952 1.47 0.224 0.11 0.0415 1.382 1.25 1.01 1.55 PRS_PLINK_1e.04 473 Diseases of the larynx and vocal cords Both 1198 12356 9 respiratory coral4 12356, 1198 3089, 294 3089, 314 3089, 288 3089, 302 -0.00964 0.03 0.748 0.126 0.99 0.934 1.05 0.0652 0.0849 0.442 0.3541 1.07 0.904 1.26 -0.0208 0.0865 0.81 0.0915 0.979 0.827 1.16 0.0213 0.0857 0.804 0.09473 1.02 0.864 1.21 PRS_PLINK_1e.04 473.1 Chronic laryngitis Both 23 310 9 respiratory coral4 310, 23 78, 6 77, 3 77, 6 78, 8 0.0637 0.204 0.755 0.1218 1.07 0.714 1.59 -0.624 0.636 0.326 0.4866 0.536 0.154 1.86 0.0233 0.539 0.965 0.01526 1.02 0.356 2.94 0.322 0.525 0.539 0.2681 1.38 0.493 3.86 PRS_PLINK_1e.04 473.3 Paralysis/spasm of vocal cords or larynx Both 254 2915 9 respiratory coral4 2915, 254 729, 58 729, 66 728, 61 729, 69 0.0607 0.0649 0.349 0.4573 1.06 0.936 1.21 0.152 0.186 0.414 0.3829 1.16 0.809 1.68 0.0512 0.189 0.786 0.1045 1.05 0.727 1.52 0.192 0.184 0.295 0.5298 1.21 0.846 1.74 PRS_PLINK_1e.04 473.4 Voice disturbance Both 917 10319 9 respiratory coral4 10319, 917 2580, 225 2580, 239 2579, 220 2580, 233 0.00268 0.0341 0.937 0.02812 1 0.938 1.07 0.0588 0.0967 0.543 0.2652 1.06 0.877 1.28 -0.0119 0.0985 0.904 0.04399 0.988 0.815 1.2 0.0381 0.0973 0.695 0.1577 1.04 0.859 1.26 PRS_PLINK_1e.04 474 Acute and chronic tonsillitis Both 598 5635 9 respiratory coral4 5635, 598 1409, 158 1409, 147 1408, 135 1409, 157 -0.00346 0.043 0.936 0.02873 0.997 0.916 1.08 -0.0758 0.121 0.53 0.2755 0.927 0.732 1.17 -0.154 0.123 0.21 0.6779 0.857 0.673 1.09 -0.00463 0.119 0.969 0.01369 0.995 0.788 1.26 PRS_PLINK_1e.04 474.1 Acute tonsillitis Both 263 2524 9 respiratory coral4 2524, 263 631, 84 631, 66 631, 49 631, 63 -0.112 0.0629 0.0741 1.13 0.894 0.79 1.01 -0.239 0.173 0.167 0.7768 0.787 0.561 1.11 -0.548 0.187 0.00337 2.472 0.578 0.4 0.834 -0.273 0.175 0.119 0.9259 0.761 0.541 1.07 PRS_PLINK_1e.04 474.2 Chronic tonsillitis and adenoiditis Both 471 4654 9 respiratory coral4 4654, 471 1164, 119 1163, 109 1163, 111 1164, 132 0.0502 0.0489 0.304 0.5175 1.05 0.956 1.16 -0.0845 0.138 0.542 0.2663 0.919 0.701 1.21 -0.0664 0.138 0.63 0.2007 0.936 0.714 1.23 0.1 0.133 0.45 0.3468 1.11 0.852 1.43 PRS_PLINK_1e.04 475 Chronic sinusitis Both 1966 14606 9 respiratory coral4 14606, 1966 3652, 475 3651, 475 3651, 506 3652, 510 0.0351 0.0243 0.148 0.8285 1.04 0.988 1.09 -0.00854 0.0693 0.902 0.04483 0.991 0.866 1.14 0.0559 0.0684 0.413 0.3838 1.06 0.925 1.21 0.0681 0.0681 0.317 0.499 1.07 0.937 1.22 PRS_PLINK_1e.04 475.9 Postnasal drip Both 353 4201 9 respiratory coral4 4201, 353 1051, 89 1050, 95 1050, 86 1050, 83 -0.0173 0.0551 0.753 0.1231 0.983 0.882 1.09 0.0593 0.152 0.697 0.1569 1.06 0.787 1.43 -0.0318 0.156 0.839 0.07642 0.969 0.713 1.32 -0.0668 0.157 0.671 0.1735 0.935 0.688 1.27 PRS_PLINK_1e.04 476 Allergic rhinitis Both 5950 14724 9 respiratory coral4 14724, 5950 3681, 1497 3681, 1428 3681, 1531 3681, 1493 0.00332 0.0155 0.83 0.08072 1 0.973 1.03 -0.0493 0.0441 0.263 0.5794 0.952 0.873 1.04 0.0172 0.0436 0.693 0.1594 1.02 0.934 1.11 -0.00973 0.0438 0.824 0.08389 0.99 0.909 1.08 PRS_PLINK_1e.04 477 Epistaxis or throat hemorrhage Both 367 5421 9 respiratory coral4 5421, 367 1356, 92 1355, 95 1355, 84 1355, 96 0.0229 0.0532 0.666 0.1763 1.02 0.922 1.14 0.0147 0.15 0.922 0.0352 1.01 0.756 1.36 -0.105 0.155 0.495 0.305 0.9 0.665 1.22 0.00825 0.15 0.956 0.01948 1.01 0.752 1.35 PRS_PLINK_1e.04 478 Throat pain Both 193 2304 9 respiratory coral4 2304, 193 576, 54 576, 46 576, 55 576, 38 -0.0726 0.0736 0.324 0.4892 0.93 0.805 1.07 -0.168 0.206 0.413 0.3837 0.845 0.565 1.26 -0.0109 0.199 0.956 0.01941 0.989 0.669 1.46 -0.356 0.218 0.102 0.9922 0.7 0.457 1.07 PRS_PLINK_1e.04 479 Other upper respiratory disease Both 2367 14685 9 respiratory coral4 14685, 2367 3672, 578 3671, 579 3671, 586 3671, 623 0.0208 0.0222 0.348 0.4584 1.02 0.978 1.07 -0.00195 0.0635 0.976 0.01076 0.998 0.881 1.13 0.0171 0.0632 0.787 0.1042 1.02 0.899 1.15 0.0785 0.0624 0.209 0.6805 1.08 0.957 1.22 PRS_PLINK_1e.04 480 Pneumonia Both 1874 19436 9 respiratory coral4 19436, 1874 4859, 478 4859, 481 4859, 507 4859, 408 -0.0474 0.0241 0.0496 1.305 0.954 0.91 1 0.00823 0.0678 0.903 0.04414 1.01 0.883 1.15 0.0544 0.067 0.417 0.3802 1.06 0.926 1.2 -0.159 0.0704 0.024 1.62 0.853 0.743 0.979 PRS_PLINK_1e.04 480.1 Bacterial pneumonia Both 322 5077 9 respiratory coral4 5077, 322 1270, 67 1269, 88 1269, 103 1269, 64 0.0176 0.0577 0.761 0.1186 1.02 0.909 1.14 0.282 0.165 0.0886 1.052 1.33 0.958 1.83 0.424 0.16 0.00815 2.089 1.53 1.12 2.09 -0.0574 0.177 0.745 0.1276 0.944 0.668 1.34 PRS_PLINK_1e.04 480.11 Pneumococcal pneumonia Both 162 2492 9 respiratory coral4 2492, 162 623, 32 623, 42 623, 53 623, 35 0.0293 0.0818 0.72 0.1425 1.03 0.877 1.21 0.27 0.236 0.254 0.5956 1.31 0.824 2.08 0.494 0.227 0.0295 1.531 1.64 1.05 2.56 0.0431 0.246 0.861 0.06507 1.04 0.645 1.69 PRS_PLINK_1e.04 480.12 Pseudomonal pneumonia Both 34 730 9 respiratory coral4 730, 34 183, 10 182, 9 182, 7 183, 8 -0.0909 0.167 0.586 0.2321 0.913 0.658 1.27 -0.0819 0.434 0.85 0.07041 0.921 0.394 2.16 -0.224 0.456 0.624 0.2051 0.799 0.327 1.95 -0.273 0.452 0.546 0.2627 0.761 0.314 1.85 PRS_PLINK_1e.04 480.13 MRSA pneumonia Both 23 542 9 respiratory coral4 542, 23 136, 5 135, 9 135, 6 136, 3 -0.0636 0.196 0.745 0.1277 0.938 0.639 1.38 0.632 0.516 0.22 0.6575 1.88 0.685 5.17 0.216 0.564 0.702 0.1539 1.24 0.411 3.75 -0.409 0.605 0.499 0.3018 0.664 0.203 2.18 PRS_PLINK_1e.04 480.2 Viral pneumonia Both 43 798 9 respiratory coral4 798, 43 200, 11 199, 13 199, 9 200, 10 -0.14 0.153 0.358 0.4457 0.869 0.644 1.17 0.152 0.395 0.701 0.1543 1.16 0.536 2.52 -0.166 0.426 0.697 0.1566 0.847 0.368 1.95 -0.17 0.425 0.689 0.1618 0.844 0.367 1.94 PRS_PLINK_1e.04 480.3 Pneumonia due to fungus (mycoses) Both 42 714 9 respiratory coral4 714, 42 179, 12 178, 15 178, 8 179, 7 -0.227 0.16 0.156 0.8078 0.797 0.582 1.09 0.241 0.385 0.533 0.2736 1.27 0.598 2.71 -0.268 0.449 0.551 0.2589 0.765 0.317 1.85 -0.493 0.448 0.271 0.567 0.611 0.254 1.47 PRS_PLINK_1e.04 480.5 Bronchopneumonia and lung abscess Both 37 539 9 respiratory coral4 539, 37 135, 7 135, 12 134, 9 135, 9 0.061 0.154 0.693 0.1594 1.06 0.785 1.44 0.303 0.484 0.531 0.2753 1.35 0.525 3.5 0.201 0.469 0.668 0.1755 1.22 0.488 3.06 0.21 0.479 0.662 0.1794 1.23 0.482 3.15 PRS_PLINK_1e.04 481 Influenza Both 535 7023 9 respiratory coral4 7023, 535 1756, 145 1756, 132 1755, 154 1756, 104 -0.0951 0.0445 0.0325 1.489 0.909 0.833 0.992 -0.0939 0.125 0.451 0.3459 0.91 0.713 1.16 0.0478 0.12 0.691 0.1607 1.05 0.829 1.33 -0.355 0.132 0.00729 2.138 0.701 0.541 0.909 PRS_PLINK_1e.04 483 Acute bronchitis and bronchiolitis Both 1255 15233 9 respiratory coral4 15233, 1255 3809, 302 3808, 309 3808, 320 3808, 323 0.000191 0.0295 0.995 0.002247 1 0.944 1.06 0.0266 0.084 0.751 0.1242 1.03 0.871 1.21 0.0578 0.0833 0.488 0.3117 1.06 0.9 1.25 0.0723 0.0832 0.385 0.4151 1.07 0.913 1.27 PRS_PLINK_1e.04 495 Asthma Both 4072 17993 9 respiratory coral4 17993, 4072 4499, 967 4498, 1007 4498, 1084 4498, 1013 0.0224 0.0176 0.202 0.694 1.02 0.988 1.06 0.0323 0.0501 0.519 0.2846 1.03 0.936 1.14 0.105 0.0494 0.0333 1.477 1.11 1.01 1.22 0.0374 0.0501 0.455 0.3416 1.04 0.941 1.15 PRS_PLINK_1e.04 495.1 Chronic obstructive asthma Both 92 1660 9 respiratory coral4 1660, 92 415, 24 415, 30 415, 18 415, 20 -0.0616 0.106 0.562 0.2503 0.94 0.763 1.16 0.196 0.279 0.481 0.3178 1.22 0.705 2.1 -0.27 0.312 0.385 0.4141 0.763 0.414 1.41 -0.1 0.303 0.741 0.1304 0.905 0.5 1.64 PRS_PLINK_1e.04 495.11 Chronic obstructive asthma with exacerbation Both 9 312 9 respiratory coral4 312, 9 78, 1 78, 4 78, 2 78, 2 0.143 0.274 0.602 0.2204 1.15 0.674 1.97 1.16 0.802 0.149 0.8277 3.18 0.661 15.3 0.801 0.842 0.341 0.4669 2.23 0.428 11.6 0.166 0.832 0.842 0.07462 1.18 0.231 6.03 PRS_PLINK_1e.04 495.2 Asthma with exacerbation Both 765 9424 9 respiratory coral4 9424, 765 2356, 181 2356, 194 2356, 205 2356, 184 0.00757 0.0377 0.841 0.07538 1.01 0.936 1.08 0.0673 0.107 0.529 0.2764 1.07 0.867 1.32 0.12 0.106 0.257 0.5908 1.13 0.916 1.39 0.0183 0.108 0.866 0.06247 1.02 0.824 1.26 PRS_PLINK_1e.04 496 Chronic airway obstruction Both 1419 13475 9 respiratory coral4 13475, 1419 3369, 336 3369, 372 3368, 393 3369, 318 -0.00954 0.028 0.734 0.1345 0.991 0.938 1.05 0.108 0.0795 0.175 0.7557 1.11 0.953 1.3 0.155 0.0787 0.0486 1.313 1.17 1 1.36 -0.0591 0.0823 0.473 0.3255 0.943 0.802 1.11 PRS_PLINK_1e.04 496.1 Emphysema Both 539 7645 9 respiratory coral4 7645, 539 1912, 128 1911, 135 1911, 146 1911, 130 0.0096 0.0443 0.828 0.08184 1.01 0.926 1.1 0.0601 0.127 0.636 0.1965 1.06 0.828 1.36 0.129 0.125 0.303 0.5188 1.14 0.89 1.45 0.0101 0.128 0.937 0.02822 1.01 0.786 1.3 PRS_PLINK_1e.04 496.2 Chronic bronchitis Both 1039 12173 9 respiratory coral4 12173, 1039 3044, 247 3043, 275 3043, 287 3043, 230 -0.0188 0.0323 0.561 0.2509 0.981 0.921 1.05 0.11 0.0913 0.229 0.6403 1.12 0.933 1.33 0.148 0.0906 0.102 0.9922 1.16 0.971 1.38 -0.0803 0.0951 0.399 0.3993 0.923 0.766 1.11 PRS_PLINK_1e.04 496.21 Obstructive chronic bronchitis Both 892 11270 9 respiratory coral4 11270, 892 2818, 220 2817, 232 2817, 243 2818, 197 -0.0332 0.0347 0.339 0.4702 0.967 0.904 1.04 0.0534 0.0978 0.585 0.233 1.05 0.871 1.28 0.0916 0.0968 0.344 0.463 1.1 0.906 1.32 -0.114 0.101 0.261 0.584 0.892 0.731 1.09 PRS_PLINK_1e.04 496.3 Bronchiectasis Both 151 2188 9 respiratory coral4 2188, 151 547, 36 547, 42 547, 49 547, 24 -0.0861 0.0824 0.296 0.5286 0.917 0.781 1.08 0.155 0.23 0.502 0.2993 1.17 0.743 1.83 0.229 0.225 0.31 0.5083 1.26 0.808 1.96 -0.392 0.263 0.136 0.8649 0.676 0.403 1.13 PRS_PLINK_1e.04 497 Bronchitis Both 688 9410 9 respiratory coral4 9410, 688 2353, 169 2352, 165 2352, 188 2353, 166 0.0183 0.0397 0.645 0.1905 1.02 0.942 1.1 -0.00699 0.113 0.951 0.02195 0.993 0.796 1.24 0.119 0.11 0.276 0.5593 1.13 0.909 1.4 -0.000685 0.113 0.995 0.002108 0.999 0.801 1.25 PRS_PLINK_1e.04 498 Acute bronchospasm Both 203 2610 9 respiratory coral4 2610, 203 653, 55 652, 46 652, 58 653, 44 -0.0785 0.0723 0.277 0.557 0.924 0.802 1.07 -0.143 0.205 0.486 0.3133 0.867 0.58 1.3 0.0902 0.194 0.643 0.192 1.09 0.748 1.6 -0.231 0.208 0.266 0.5754 0.793 0.528 1.19 PRS_PLINK_1e.04 499 Cystic fibrosis Both 68 819 9 respiratory coral4 819, 68 205, 12 205, 25 204, 17 205, 14 -0.0467 0.129 0.717 0.1443 0.954 0.741 1.23 0.662 0.349 0.0579 1.237 1.94 0.978 3.84 0.3 0.371 0.418 0.3793 1.35 0.653 2.79 0.0972 0.388 0.802 0.09575 1.1 0.515 2.36 PRS_PLINK_1e.04 500 Lung disease due to external agents Both 164 2325 9 respiratory coral4 2325, 164 582, 36 581, 45 581, 47 581, 36 0.0227 0.0787 0.773 0.1117 1.02 0.877 1.19 0.2 0.228 0.38 0.4197 1.22 0.781 1.91 0.263 0.224 0.241 0.6177 1.3 0.838 2.02 -0.01 0.238 0.967 0.01478 0.99 0.62 1.58 PRS_PLINK_1e.04 500.1 Extrinsic allergic alveolitis Both 24 389 9 respiratory coral4 389, 24 98, 6 97, 5 97, 7 97, 6 0.11 0.201 0.585 0.2325 1.12 0.752 1.66 -0.0736 0.556 0.895 0.04833 0.929 0.312 2.76 0.184 0.528 0.727 0.1385 1.2 0.427 3.39 0.044 0.537 0.935 0.0293 1.04 0.365 2.99 PRS_PLINK_1e.04 500.2 Pneumoconiosis Both 12 252 9 respiratory coral4 252, 12 63, 1 63, 5 63, 3 63, 3 0.158 0.26 0.543 0.2654 1.17 0.704 1.95 1.26 0.87 0.147 0.833 3.53 0.642 19.4 0.952 0.827 0.25 0.6025 2.59 0.512 13.1 1.05 0.879 0.231 0.6369 2.87 0.512 16.1 PRS_PLINK_1e.04 501 Pneumonitis due to inhalation of food or vomitus Both 130 2509 9 respiratory coral4 2509, 130 628, 30 627, 31 627, 39 627, 30 0.0539 0.0883 0.542 0.2663 1.06 0.888 1.25 0.0386 0.256 0.88 0.05544 1.04 0.629 1.72 0.25 0.244 0.306 0.5146 1.28 0.796 2.07 0.00112 0.258 0.997 0.001506 1 0.604 1.66 PRS_PLINK_1e.04 502 Postinflammatory pulmonary fibrosis Both 207 3266 9 respiratory coral4 3266, 207 817, 51 816, 59 816, 57 817, 40 -0.0395 0.0712 0.58 0.2368 0.961 0.836 1.11 0.149 0.194 0.443 0.3531 1.16 0.793 1.7 0.104 0.196 0.595 0.2256 1.11 0.756 1.63 -0.219 0.213 0.304 0.517 0.803 0.529 1.22 PRS_PLINK_1e.04 503 Pulmonary congestion and hypostasis Both 106 3370 9 respiratory coral4 3370, 106 843, 32 842, 32 842, 19 843, 23 -0.0561 0.097 0.563 0.2493 0.945 0.782 1.14 -0.0105 0.248 0.966 0.01494 0.99 0.608 1.61 -0.555 0.285 0.0515 1.288 0.574 0.328 1 -0.307 0.272 0.259 0.5865 0.736 0.432 1.25 PRS_PLINK_1e.04 504 Other alveolar and parietoalveolar pneumonopathy Both 145 2358 9 respiratory coral4 2358, 145 590, 35 589, 43 589, 42 590, 25 -0.0671 0.084 0.424 0.3724 0.935 0.793 1.1 0.207 0.232 0.372 0.4291 1.23 0.781 1.94 0.182 0.231 0.432 0.365 1.2 0.763 1.88 -0.29 0.26 0.266 0.575 0.749 0.449 1.25 PRS_PLINK_1e.04 504.1 Idiopathic fibrosing alveolitis Both 75 1177 9 respiratory coral4 1177, 75 295, 19 294, 22 294, 23 294, 11 -0.0813 0.116 0.484 0.315 0.922 0.734 1.16 0.176 0.317 0.578 0.2382 1.19 0.641 2.22 0.221 0.313 0.48 0.3185 1.25 0.675 2.3 -0.543 0.365 0.137 0.864 0.581 0.284 1.19 PRS_PLINK_1e.04 505 Other pulmonary inflamation or edema Both 271 6539 9 respiratory coral4 6539, 271 1635, 72 1635, 72 1634, 63 1635, 64 -0.0251 0.061 0.681 0.167 0.975 0.865 1.1 -0.00901 0.169 0.957 0.01888 0.991 0.712 1.38 -0.136 0.174 0.435 0.3612 0.873 0.621 1.23 -0.144 0.173 0.408 0.3899 0.866 0.617 1.22 PRS_PLINK_1e.04 506 Empyema and pneumothorax Both 830 11812 9 respiratory coral4 11812, 830 2953, 199 2953, 204 2953, 232 2953, 195 0.00477 0.0357 0.894 0.04873 1 0.937 1.08 0.026 0.103 0.8 0.09696 1.03 0.839 1.25 0.147 0.0997 0.14 0.8527 1.16 0.953 1.41 -0.0214 0.104 0.836 0.07769 0.979 0.799 1.2 PRS_PLINK_1e.04 507 Pleurisy; pleural effusion Both 739 12103 9 respiratory coral4 12103, 739 3026, 174 3026, 201 3025, 189 3026, 175 -0.00968 0.0379 0.798 0.09783 0.99 0.919 1.07 0.148 0.106 0.163 0.7888 1.16 0.942 1.43 0.087 0.108 0.42 0.377 1.09 0.883 1.35 0.0115 0.11 0.916 0.03795 1.01 0.816 1.25 PRS_PLINK_1e.04 508 Pulmonary collapse; interstitial and compensatory emphysema Both 594 10133 9 respiratory coral4 10133, 594 2534, 142 2533, 157 2533, 162 2533, 133 0.0132 0.0421 0.754 0.1225 1.01 0.933 1.1 0.105 0.118 0.375 0.4259 1.11 0.881 1.4 0.137 0.118 0.245 0.6103 1.15 0.91 1.44 -0.0649 0.123 0.598 0.2232 0.937 0.736 1.19 PRS_PLINK_1e.04 509 Respiratory failure, insufficiency, arrest Both 817 14043 9 respiratory coral4 14043, 817 3511, 231 3511, 218 3510, 214 3511, 154 -0.104 0.0355 0.00344 2.464 0.901 0.841 0.966 -0.056 0.097 0.564 0.249 0.946 0.782 1.14 -0.0684 0.0975 0.483 0.3159 0.934 0.771 1.13 -0.395 0.106 0.000201 3.697 0.674 0.547 0.83 PRS_PLINK_1e.04 509.1 Respiratory failure Both 385 8239 9 respiratory coral4 8239, 385 2060, 115 2060, 100 2059, 104 2060, 66 -0.134 0.0511 0.00852 2.069 0.874 0.791 0.966 -0.145 0.139 0.298 0.5259 0.865 0.659 1.14 -0.1 0.138 0.467 0.3303 0.905 0.691 1.19 -0.546 0.156 0.000465 3.333 0.579 0.427 0.786 PRS_PLINK_1e.04 509.2 Respiratory insufficiency Both 218 5060 9 respiratory coral4 5060, 218 1265, 63 1265, 55 1265, 58 1265, 42 -0.0678 0.0675 0.315 0.5013 0.934 0.819 1.07 -0.139 0.186 0.456 0.3409 0.871 0.604 1.25 -0.0773 0.184 0.674 0.171 0.926 0.645 1.33 -0.417 0.2 0.0367 1.436 0.659 0.446 0.974 PRS_PLINK_1e.04 509.3 Pulmonary insufficiency or respiratory failure following trauma and surgery Both 324 7086 9 respiratory coral4 7086, 324 1772, 77 1771, 88 1771, 89 1772, 70 -0.0188 0.0562 0.738 0.132 0.981 0.879 1.1 0.125 0.158 0.427 0.3695 1.13 0.832 1.54 0.157 0.158 0.321 0.494 1.17 0.858 1.6 -0.0986 0.166 0.553 0.257 0.906 0.654 1.26 PRS_PLINK_1e.04 509.8 Dependence on respirator [Ventilator] or supplemental oxygen Both 301 7171 9 respiratory coral4 7171, 301 1793, 89 1793, 85 1792, 78 1793, 49 -0.149 0.0569 0.00899 2.046 0.862 0.771 0.964 -0.0445 0.154 0.772 0.1123 0.957 0.708 1.29 -0.135 0.157 0.391 0.4078 0.874 0.643 1.19 -0.595 0.178 0.000854 3.068 0.552 0.389 0.783 PRS_PLINK_1e.04 510 Other diseases of lung Both 1602 17229 9 respiratory coral4 17229, 1602 4308, 363 4307, 443 4307, 405 4307, 391 0.025 0.0263 0.342 0.4656 1.03 0.974 1.08 0.203 0.0743 0.00637 2.196 1.22 1.06 1.42 0.112 0.0758 0.138 0.8589 1.12 0.964 1.3 0.077 0.0763 0.313 0.5049 1.08 0.93 1.25 PRS_PLINK_1e.04 510.2 Lung transplant Both 20 798 9 respiratory coral4 798, 20 200, 4 199, 9 199, 5 200, 2 -0.22 0.201 0.272 0.5654 0.802 0.541 1.19 0.651 0.531 0.221 0.6559 1.92 0.676 5.43 0.155 0.572 0.786 0.1045 1.17 0.381 3.58 -0.412 0.661 0.533 0.2732 0.662 0.181 2.42 PRS_PLINK_1e.04 512 Other symptoms of respiratory system Both 7016 16446 9 respiratory coral4 16446, 7016 4112, 1766 4111, 1738 4111, 1788 4112, 1723 -0.00524 0.0143 0.715 0.1457 0.995 0.967 1.02 -0.0142 0.0406 0.727 0.1387 0.986 0.91 1.07 0.00956 0.0404 0.813 0.08999 1.01 0.933 1.09 -0.0282 0.0407 0.488 0.3114 0.972 0.898 1.05 PRS_PLINK_1e.04 512.1 Wheezing Both 423 7101 9 respiratory coral4 7101, 423 1776, 108 1775, 110 1775, 115 1775, 90 -0.0596 0.0497 0.23 0.6382 0.942 0.855 1.04 -0.000911 0.139 0.995 0.002281 0.999 0.761 1.31 0.0646 0.137 0.638 0.1952 1.07 0.815 1.4 -0.183 0.145 0.207 0.684 0.832 0.626 1.11 PRS_PLINK_1e.04 512.2 Painful respiration Both 843 11797 9 respiratory coral4 11797, 843 2950, 228 2949, 201 2949, 233 2949, 181 -0.0539 0.0355 0.129 0.8887 0.948 0.884 1.02 -0.135 0.1 0.178 0.7498 0.874 0.718 1.06 0.02 0.0966 0.836 0.07769 1.02 0.844 1.23 -0.23 0.103 0.025 1.602 0.795 0.65 0.972 PRS_PLINK_1e.04 512.3 Abnormal chest sounds Both 66 1162 9 respiratory coral4 1162, 66 291, 14 290, 13 290, 21 291, 18 0.13 0.125 0.299 0.525 1.14 0.892 1.45 -0.0544 0.371 0.883 0.0538 0.947 0.457 1.96 0.355 0.338 0.294 0.5319 1.43 0.735 2.77 0.204 0.346 0.557 0.2544 1.23 0.622 2.42 PRS_PLINK_1e.04 512.7 Shortness of breath Both 2975 16377 9 respiratory coral4 16377, 2975 4095, 756 4094, 739 4094, 771 4094, 708 -0.0202 0.02 0.313 0.5047 0.98 0.942 1.02 -0.018 0.0567 0.751 0.1246 0.982 0.879 1.1 0.0129 0.0562 0.819 0.08673 1.01 0.907 1.13 -0.0689 0.0572 0.228 0.6415 0.933 0.835 1.04 PRS_PLINK_1e.04 512.8 Cough Both 3544 16441 9 respiratory coral4 16441, 3544 4111, 891 4110, 849 4110, 934 4110, 870 -0.000911 0.0187 0.961 0.01724 0.999 0.963 1.04 -0.0486 0.0533 0.362 0.4418 0.953 0.858 1.06 0.0389 0.0522 0.457 0.3405 1.04 0.939 1.15 -0.029 0.0529 0.584 0.2335 0.971 0.876 1.08 PRS_PLINK_1e.04 512.9 Other dyspnea Both 3480 16397 9 respiratory coral4 16397, 3480 4100, 889 4099, 865 4099, 873 4099, 853 -0.015 0.0187 0.423 0.3737 0.985 0.95 1.02 -0.0229 0.0529 0.666 0.1767 0.977 0.881 1.08 -0.0238 0.0528 0.652 0.186 0.976 0.88 1.08 -0.0437 0.053 0.409 0.3879 0.957 0.863 1.06 PRS_PLINK_1e.04 513 Respiratory abnormalities Both 4287 19153 9 respiratory coral4 19153, 4287 4789, 1052 4788, 1080 4788, 1125 4788, 1029 -0.00329 0.017 0.846 0.07253 0.997 0.964 1.03 0.0284 0.0481 0.556 0.2552 1.03 0.936 1.13 0.0647 0.0477 0.175 0.756 1.07 0.972 1.17 -0.026 0.0486 0.592 0.2276 0.974 0.886 1.07 PRS_PLINK_1e.04 513.3 Hypoventilation Both 223 4032 9 respiratory coral4 4032, 223 1008, 64 1008, 42 1008, 68 1008, 49 -0.0698 0.0687 0.309 0.5097 0.933 0.815 1.07 -0.395 0.2 0.0481 1.318 0.673 0.455 0.997 0.0767 0.178 0.667 0.1759 1.08 0.761 1.53 -0.232 0.192 0.228 0.6417 0.793 0.544 1.16 PRS_PLINK_1e.04 513.31 Apnea Both 150 2264 9 respiratory coral4 2264, 150 566, 40 566, 28 566, 46 566, 36 -0.0271 0.0831 0.744 0.1284 0.973 0.827 1.15 -0.308 0.248 0.214 0.6697 0.735 0.452 1.19 0.138 0.221 0.533 0.273 1.15 0.744 1.77 -0.078 0.234 0.739 0.1313 0.925 0.585 1.46 PRS_PLINK_1e.04 513.32 Orthopnea Both 32 844 9 respiratory coral4 844, 32 211, 11 211, 7 211, 11 211, 3 -0.326 0.176 0.0638 1.195 0.722 0.511 1.02 -0.458 0.453 0.313 0.505 0.633 0.26 1.54 0.0984 0.428 0.818 0.08714 1.1 0.477 2.55 -1.22 0.566 0.0312 1.506 0.295 0.0975 0.896 PRS_PLINK_1e.04 513.4 Hyperventilation Both 101 2329 9 respiratory coral4 2329, 101 583, 25 582, 30 582, 21 582, 25 0.0109 0.101 0.914 0.03924 1.01 0.83 1.23 0.18 0.267 0.501 0.3005 1.2 0.709 2.02 -0.147 0.291 0.613 0.2122 0.863 0.488 1.53 0.0209 0.281 0.941 0.02656 1.02 0.588 1.77 PRS_PLINK_1e.04 513.8 Disorders of diaphragm Both 63 1127 9 respiratory coral4 1127, 63 282, 14 282, 12 281, 22 282, 15 -0.0122 0.124 0.922 0.03543 0.988 0.775 1.26 -0.041 0.378 0.914 0.03917 0.96 0.457 2.01 0.455 0.336 0.175 0.7574 1.58 0.817 3.04 0.138 0.363 0.704 0.1525 1.15 0.564 2.34 PRS_PLINK_1e.04 514 Abnormal findings examination of lungs Both 1710 16312 9 respiratory coral4 16312, 1710 4077, 381 4078, 420 4078, 447 4078, 462 0.065 0.0256 0.0111 1.953 1.07 1.01 1.12 0.102 0.0743 0.17 0.7705 1.11 0.957 1.28 0.162 0.0734 0.0273 1.564 1.18 1.02 1.36 0.198 0.0729 0.00672 2.173 1.22 1.06 1.41 PRS_PLINK_1e.04 514.1 Abnormal results of function study of pulmonary system Both 44 996 9 respiratory coral4 996, 44 249, 11 249, 18 249, 7 249, 8 -0.198 0.148 0.183 0.738 0.821 0.613 1.1 0.476 0.371 0.199 0.7005 1.61 0.778 3.33 -0.467 0.441 0.29 0.538 0.627 0.264 1.49 -0.35 0.43 0.416 0.3807 0.705 0.304 1.64 PRS_PLINK_1e.04 514.2 Solitary pulmonary nodule Both 970 11420 9 respiratory coral4 11420, 970 2855, 231 2855, 224 2855, 247 2855, 268 0.0443 0.0335 0.186 0.7296 1.05 0.979 1.12 -0.0262 0.0971 0.787 0.104 0.974 0.805 1.18 0.0713 0.095 0.453 0.3439 1.07 0.891 1.29 0.16 0.0935 0.0868 1.061 1.17 0.977 1.41 PRS_PLINK_1e.04 516 Abnormal sputum Both 190 3071 9 respiratory coral4 3071, 190 768, 39 768, 46 767, 56 768, 49 0.0494 0.0737 0.502 0.2989 1.05 0.909 1.21 0.133 0.219 0.545 0.2635 1.14 0.743 1.75 0.372 0.211 0.0769 1.114 1.45 0.961 2.19 0.194 0.216 0.371 0.4308 1.21 0.794 1.85 PRS_PLINK_1e.04 516.1 Hemoptysis Both 163 2645 9 respiratory coral4 2645, 163 662, 32 661, 42 661, 50 661, 39 0.0333 0.079 0.674 0.1716 1.03 0.886 1.21 0.26 0.236 0.27 0.5687 1.3 0.817 2.06 0.451 0.229 0.0487 1.312 1.57 1 2.46 0.156 0.239 0.513 0.2903 1.17 0.732 1.87 PRS_PLINK_1e.04 519 Other diseases of respiratory system, not elsewhere classified Both 2042 20344 9 respiratory coral4 20344, 2042 5085, 519 5086, 506 5086, 549 5086, 468 -0.0328 0.0232 0.158 0.8013 0.968 0.925 1.01 -0.0255 0.0657 0.698 0.1562 0.975 0.857 1.11 0.059 0.0645 0.36 0.4434 1.06 0.935 1.2 -0.11 0.0669 0.1 0.9995 0.896 0.786 1.02 PRS_PLINK_1e.04 519.1 Tracheostomy complications Both 62 971 9 respiratory coral4 971, 62 243, 15 243, 17 242, 19 243, 11 -0.0828 0.126 0.512 0.2906 0.921 0.719 1.18 0.131 0.352 0.709 0.1493 1.14 0.572 2.27 0.199 0.343 0.561 0.2514 1.22 0.624 2.39 -0.321 0.384 0.404 0.394 0.726 0.342 1.54 PRS_PLINK_1e.04 519.2 Respiratory complications Both 110 2009 9 respiratory coral4 2009, 110 503, 29 502, 24 502, 29 502, 28 0.0108 0.0947 0.91 0.04119 1.01 0.84 1.22 -0.136 0.276 0.621 0.2068 0.872 0.508 1.5 -0.0268 0.263 0.919 0.03683 0.974 0.582 1.63 0.00245 0.265 0.993 0.003215 1 0.596 1.69 PRS_PLINK_1e.04 519.8 Other diseases of respiratory system, NEC Both 569 7545 9 respiratory coral4 7545, 569 1887, 132 1886, 134 1886, 167 1886, 136 0.0213 0.0436 0.626 0.2038 1.02 0.938 1.11 0.0129 0.126 0.918 0.03701 1.01 0.791 1.3 0.247 0.12 0.0401 1.397 1.28 1.01 1.62 0.025 0.126 0.842 0.0746 1.03 0.802 1.31 PRS_PLINK_1e.04 519.9 Symptoms involving respiratory system and other chest symptoms Both 1375 16705 9 respiratory coral4 16705, 1375 4176, 358 4176, 355 4176, 360 4176, 302 -0.0531 0.0279 0.0571 1.243 0.948 0.898 1 -0.00652 0.078 0.933 0.02994 0.993 0.853 1.16 0.012 0.0779 0.878 0.05664 1.01 0.869 1.18 -0.169 0.0811 0.0377 1.423 0.845 0.721 0.99 PRS_PLINK_1e.04 520 Disorders of tooth development Both 214 2162 10 digestive chartreuse4 2162, 214 540, 52 540, 52 540, 57 541, 53 0.0498 0.0703 0.479 0.32 1.05 0.916 1.21 -0.00656 0.203 0.974 0.01137 0.993 0.668 1.48 0.091 0.199 0.647 0.1892 1.1 0.742 1.62 -0.0203 0.202 0.92 0.03619 0.98 0.66 1.46 PRS_PLINK_1e.04 520.1 Hereditary disturbances in tooth structure Both 81 791 10 digestive chartreuse4 791, 81 198, 19 198, 13 197, 29 198, 20 0.157 0.117 0.179 0.7462 1.17 0.93 1.47 -0.43 0.364 0.238 0.6243 0.651 0.319 1.33 0.41 0.308 0.183 0.7365 1.51 0.824 2.76 0.0017 0.329 0.996 0.001797 1 0.526 1.91 PRS_PLINK_1e.04 520.2 Disturbances in tooth eruption Both 146 1460 10 digestive chartreuse4 1460, 146 364, 36 365, 40 365, 34 365, 36 0.0104 0.0846 0.902 0.04462 1.01 0.856 1.19 0.111 0.237 0.641 0.1929 1.12 0.701 1.78 -0.03 0.245 0.902 0.04459 0.97 0.601 1.57 -0.00735 0.242 0.976 0.01063 0.993 0.617 1.6 PRS_PLINK_1e.04 521 Diseases of hard tissues of teeth Both 357 4494 10 digestive chartreuse4 4494, 357 1123, 88 1123, 94 1123, 92 1124, 83 -0.00254 0.0551 0.963 0.01625 0.997 0.895 1.11 0.0759 0.153 0.62 0.2074 1.08 0.799 1.46 0.0611 0.154 0.692 0.1602 1.06 0.786 1.44 -0.0452 0.158 0.774 0.1111 0.956 0.702 1.3 PRS_PLINK_1e.04 521.1 Dental caries Both 332 4155 10 digestive chartreuse4 4155, 332 1038, 81 1039, 87 1038, 85 1039, 79 -0.000498 0.0576 0.993 0.003007 1 0.893 1.12 0.0767 0.159 0.63 0.2003 1.08 0.79 1.48 0.059 0.161 0.713 0.1467 1.06 0.774 1.45 -0.00614 0.163 0.97 0.01325 0.994 0.722 1.37 PRS_PLINK_1e.04 521.2 Dental abrasion, erosion and attrition Both 22 272 10 digestive chartreuse4 272, 22 68, 6 68, 5 68, 8 68, 3 -0.222 0.22 0.312 0.5052 0.801 0.52 1.23 -0.367 0.605 0.544 0.2647 0.693 0.212 2.27 0.121 0.537 0.822 0.08498 1.13 0.394 3.23 -0.574 0.625 0.359 0.4453 0.563 0.165 1.92 PRS_PLINK_1e.04 522 Diseases of pulp and periapical tissues Both 221 2814 10 digestive chartreuse4 2814, 221 704, 59 703, 48 703, 56 704, 58 0.00594 0.0707 0.933 0.03011 1.01 0.876 1.16 -0.213 0.199 0.284 0.5468 0.808 0.547 1.19 -0.0386 0.191 0.84 0.07563 0.962 0.661 1.4 -0.0276 0.19 0.885 0.05316 0.973 0.67 1.41 PRS_PLINK_1e.04 522.5 Periapical abscess Both 184 2394 10 digestive chartreuse4 2394, 184 599, 47 598, 40 598, 49 599, 48 0.0174 0.0771 0.822 0.08537 1.02 0.875 1.18 -0.178 0.219 0.417 0.3804 0.837 0.544 1.29 0.0517 0.209 0.804 0.09466 1.05 0.7 1.58 0.00633 0.21 0.976 0.01055 1.01 0.666 1.52 PRS_PLINK_1e.04 523 Gingival and periodontal diseases Both 264 3493 10 digestive chartreuse4 3493, 264 873, 66 873, 59 873, 67 873, 72 0.0866 0.0658 0.188 0.7258 1.09 0.959 1.24 -0.121 0.183 0.507 0.2949 0.886 0.619 1.27 0.00431 0.178 0.981 0.008485 1 0.709 1.42 0.0951 0.176 0.588 0.2305 1.1 0.779 1.55 PRS_PLINK_1e.04 523.1 Gingivitis Both 47 733 10 digestive chartreuse4 733, 47 184, 15 183, 12 183, 10 183, 10 -0.103 0.138 0.456 0.3406 0.902 0.689 1.18 -0.231 0.386 0.551 0.2592 0.794 0.372 1.69 -0.33 0.399 0.409 0.3886 0.719 0.329 1.57 -0.361 0.399 0.366 0.4369 0.697 0.319 1.52 PRS_PLINK_1e.04 523.3 Periodontitis (acute or chronic) Both 138 1808 10 digestive chartreuse4 1808, 138 451, 39 452, 27 452, 36 452, 36 0.0338 0.0909 0.71 0.1489 1.03 0.866 1.24 -0.384 0.253 0.129 0.8907 0.681 0.415 1.12 -0.0838 0.235 0.721 0.1418 0.92 0.58 1.46 -0.0597 0.236 0.8 0.0968 0.942 0.593 1.5 PRS_PLINK_1e.04 523.31 Acute periodontitis Both 123 1578 10 digestive chartreuse4 1578, 123 394, 34 394, 25 394, 32 395, 32 0.00973 0.0969 0.92 0.0362 1.01 0.835 1.22 -0.336 0.266 0.206 0.6868 0.714 0.424 1.2 -0.0755 0.251 0.763 0.1172 0.927 0.567 1.52 -0.0692 0.251 0.783 0.1062 0.933 0.57 1.53 PRS_PLINK_1e.04 523.32 Chronic periodontitis Both 45 517 10 digestive chartreuse4 517, 45 130, 15 129, 9 129, 10 129, 11 0.133 0.157 0.397 0.401 1.14 0.84 1.55 -0.444 0.414 0.283 0.5478 0.641 0.285 1.44 -0.32 0.406 0.429 0.3671 0.726 0.328 1.61 -0.263 0.395 0.505 0.2965 0.769 0.354 1.67 PRS_PLINK_1e.04 524 Dentofacial anomalies, including malocclusion Both 261 2450 10 digestive chartreuse4 2450, 261 613, 57 612, 60 612, 68 613, 76 0.141 0.0667 0.035 1.456 1.15 1.01 1.31 0.051 0.192 0.79 0.1022 1.05 0.722 1.53 0.186 0.187 0.32 0.4949 1.2 0.835 1.74 0.267 0.183 0.144 0.8402 1.31 0.913 1.87 PRS_PLINK_1e.04 524.3 Anomalies of tooth position/malocclusion Both 174 1600 10 digestive chartreuse4 1600, 174 400, 37 400, 36 400, 49 400, 52 0.169 0.0801 0.0353 1.452 1.18 1.01 1.38 0.000596 0.242 0.998 0.0008528 1 0.622 1.61 0.28 0.225 0.213 0.6714 1.32 0.851 2.06 0.343 0.224 0.127 0.8969 1.41 0.907 2.19 PRS_PLINK_1e.04 525 Other diseases of the teeth and supporting structures Both 455 5459 10 digestive chartreuse4 5459, 455 1365, 120 1365, 101 1364, 118 1365, 116 0.0471 0.049 0.337 0.4726 1.05 0.952 1.15 -0.17 0.139 0.224 0.6499 0.844 0.642 1.11 -0.0112 0.134 0.933 0.02994 0.989 0.76 1.29 -0.0244 0.135 0.857 0.0672 0.976 0.749 1.27 PRS_PLINK_1e.04 525.1 Loss of teeth or edentulism Both 168 1908 10 digestive chartreuse4 1908, 168 477, 47 477, 37 477, 47 477, 37 0.0242 0.0813 0.766 0.1157 1.02 0.874 1.2 -0.255 0.226 0.259 0.5868 0.775 0.498 1.21 0.0103 0.213 0.962 0.017 1.01 0.665 1.53 -0.22 0.226 0.329 0.4832 0.802 0.516 1.25 PRS_PLINK_1e.04 526 Diseases of the jaws Both 1431 14513 10 digestive chartreuse4 14513, 1431 3628, 337 3628, 347 3628, 364 3628, 383 0.0489 0.028 0.0811 1.091 1.05 0.994 1.11 0.0241 0.0799 0.763 0.1174 1.02 0.876 1.2 0.0812 0.0791 0.304 0.5168 1.08 0.929 1.27 0.129 0.0782 0.0991 1.004 1.14 0.976 1.33 PRS_PLINK_1e.04 526.1 Cysts of the jaws Both 135 1319 10 digestive chartreuse4 1319, 135 330, 36 330, 25 329, 44 330, 30 -0.0504 0.09 0.576 0.2399 0.951 0.797 1.13 -0.361 0.267 0.177 0.7517 0.697 0.413 1.18 0.215 0.236 0.362 0.4412 1.24 0.781 1.97 -0.176 0.255 0.491 0.3091 0.839 0.509 1.38 PRS_PLINK_1e.04 526.3 Anomalies of jaw size/symmetry Both 201 1720 10 digestive chartreuse4 1720, 201 430, 47 430, 43 430, 52 430, 59 0.11 0.0773 0.154 0.8136 1.12 0.96 1.3 -0.0897 0.219 0.682 0.1663 0.914 0.596 1.4 0.0742 0.21 0.724 0.14 1.08 0.713 1.63 0.231 0.206 0.262 0.5817 1.26 0.841 1.89 PRS_PLINK_1e.04 526.4 Temporomandibular joint disorders Both 845 8630 10 digestive chartreuse4 8630, 845 2157, 192 2157, 217 2157, 205 2158, 231 0.0776 0.0369 0.0356 1.449 1.08 1.01 1.16 0.12 0.103 0.244 0.6127 1.13 0.921 1.38 0.065 0.105 0.534 0.2723 1.07 0.869 1.31 0.183 0.102 0.0728 1.138 1.2 0.983 1.47 PRS_PLINK_1e.04 526.41 Temporomandibular joint disorder, unspecified Both 683 6893 10 digestive chartreuse4 6893, 683 1723, 158 1723, 174 1723, 166 1723, 185 0.0665 0.041 0.105 0.979 1.07 0.986 1.16 0.0924 0.115 0.42 0.377 1.1 0.876 1.37 0.0538 0.116 0.642 0.1924 1.06 0.841 1.32 0.157 0.113 0.165 0.7824 1.17 0.937 1.46 PRS_PLINK_1e.04 526.42 Arthralgia/ankylosis of temporomandibular joint Both 452 4504 10 digestive chartreuse4 4504, 452 1126, 100 1126, 128 1126, 101 1126, 123 0.0633 0.0507 0.212 0.6743 1.07 0.965 1.18 0.242 0.139 0.0823 1.085 1.27 0.969 1.67 0.00626 0.146 0.966 0.01511 1.01 0.756 1.34 0.208 0.14 0.138 0.8614 1.23 0.935 1.62 PRS_PLINK_1e.04 526.5 Inflammatory conditions of jaw Both 130 1348 10 digestive chartreuse4 1348, 130 337, 21 337, 34 337, 40 337, 35 0.14 0.0912 0.124 0.9049 1.15 0.962 1.38 0.498 0.284 0.0798 1.098 1.65 0.943 2.87 0.644 0.275 0.0191 1.719 1.9 1.11 3.26 0.474 0.28 0.0901 1.045 1.61 0.929 2.78 PRS_PLINK_1e.04 526.8 Exostosis of jaw Both 21 221 10 digestive chartreuse4 221, 21 56, 4 55, 8 55, 3 55, 6 0.194 0.227 0.391 0.4074 1.21 0.779 1.89 0.712 0.59 0.228 0.6426 2.04 0.641 6.48 0.136 0.734 0.853 0.06915 1.15 0.272 4.83 0.412 0.623 0.508 0.2944 1.51 0.446 5.12 PRS_PLINK_1e.04 526.9 Jaw disease NOS Both 234 2421 10 digestive chartreuse4 2421, 234 606, 46 605, 62 605, 63 605, 63 0.0882 0.0688 0.2 0.6994 1.09 0.954 1.25 0.287 0.201 0.154 0.8136 1.33 0.898 1.98 0.316 0.2 0.114 0.9413 1.37 0.926 2.03 0.321 0.199 0.107 0.9705 1.38 0.933 2.04 PRS_PLINK_1e.04 527 Diseases of the salivary glands Both 711 7801 10 digestive chartreuse4 7801, 711 1951, 174 1950, 180 1950, 200 1950, 157 0.00172 0.0392 0.965 0.01544 1 0.928 1.08 0.0422 0.111 0.703 0.153 1.04 0.84 1.3 0.145 0.108 0.18 0.7449 1.16 0.935 1.43 -0.106 0.114 0.354 0.4506 0.9 0.719 1.13 PRS_PLINK_1e.04 527.1 Hypertrophy of salivary gland Both 28 254 10 digestive chartreuse4 254, 28 64, 12 63, 4 63, 9 64, 3 -0.305 0.188 0.104 0.983 0.737 0.51 1.06 -0.769 0.557 0.167 0.7767 0.463 0.156 1.38 -0.324 0.487 0.505 0.2965 0.723 0.278 1.88 -1.38 0.618 0.0257 1.591 0.252 0.075 0.846 PRS_PLINK_1e.04 527.2 Sialoadenitis Both 170 1836 10 digestive chartreuse4 1836, 170 459, 41 459, 42 459, 48 459, 39 0.0422 0.0818 0.606 0.2175 1.04 0.889 1.22 0.0361 0.227 0.874 0.05865 1.04 0.664 1.62 0.152 0.219 0.486 0.313 1.16 0.758 1.79 -0.0617 0.229 0.788 0.1035 0.94 0.6 1.47 PRS_PLINK_1e.04 527.7 Disturbance of salivary secretion Both 339 3754 10 digestive chartreuse4 3754, 339 939, 87 938, 85 938, 96 939, 71 -0.0441 0.0558 0.429 0.3674 0.957 0.858 1.07 -0.0154 0.158 0.923 0.03503 0.985 0.722 1.34 0.107 0.154 0.486 0.3136 1.11 0.823 1.51 -0.201 0.165 0.224 0.6501 0.818 0.592 1.13 PRS_PLINK_1e.04 527.8 Other specified diseases of the salivary glands Both 99 1049 10 digestive chartreuse4 1049, 99 263, 22 262, 31 262, 23 262, 23 -0.0246 0.103 0.812 0.09031 0.976 0.797 1.2 0.329 0.287 0.253 0.5969 1.39 0.791 2.44 0.0547 0.301 0.856 0.06763 1.06 0.585 1.91 0.0935 0.305 0.759 0.1196 1.1 0.604 2 PRS_PLINK_1e.04 528 Diseases of the oral soft tissues, excluding lesions specific for gingiva and tongue Both 1205 12542 10 digestive chartreuse4 12542, 1205 3136, 294 3135, 300 3135, 305 3136, 306 0.0164 0.03 0.584 0.2336 1.02 0.959 1.08 0.0191 0.0857 0.824 0.08408 1.02 0.862 1.21 0.0394 0.0853 0.644 0.1912 1.04 0.88 1.23 0.0424 0.0853 0.619 0.2083 1.04 0.883 1.23 PRS_PLINK_1e.04 528.1 Stomatitis and mucositis Both 292 3254 10 digestive chartreuse4 3254, 292 814, 69 813, 77 813, 74 814, 72 0.00329 0.0603 0.956 0.01932 1 0.891 1.13 0.109 0.171 0.524 0.2805 1.12 0.797 1.56 0.0561 0.173 0.745 0.1276 1.06 0.754 1.48 0.0271 0.174 0.876 0.05735 1.03 0.731 1.44 PRS_PLINK_1e.04 528.11 Stomatitis and mucositis (ulcerative) Both 85 997 10 digestive chartreuse4 997, 85 250, 16 249, 27 249, 18 249, 24 0.0936 0.113 0.409 0.3883 1.1 0.879 1.37 0.515 0.316 0.103 0.9868 1.67 0.901 3.11 0.0751 0.338 0.824 0.08402 1.08 0.556 2.09 0.403 0.322 0.21 0.6772 1.5 0.796 2.81 PRS_PLINK_1e.04 528.12 Oral aphthae Both 106 1164 10 digestive chartreuse4 1164, 106 291, 33 291, 25 291, 19 291, 29 -0.0798 0.102 0.432 0.3643 0.923 0.757 1.13 -0.273 0.27 0.312 0.5056 0.761 0.448 1.29 -0.514 0.292 0.0776 1.11 0.598 0.338 1.06 -0.137 0.264 0.605 0.2181 0.872 0.52 1.46 PRS_PLINK_1e.04 528.3 Cellulitis and abscess of oral soft tissues Both 110 1209 10 digestive chartreuse4 1209, 110 303, 26 302, 24 302, 31 302, 29 0.0444 0.0983 0.651 0.1861 1.05 0.862 1.27 -0.0557 0.288 0.847 0.07228 0.946 0.538 1.66 0.217 0.274 0.429 0.3674 1.24 0.725 2.13 0.0864 0.274 0.753 0.1233 1.09 0.637 1.87 PRS_PLINK_1e.04 528.4 Cysts of oral soft tissues Both 68 634 10 digestive chartreuse4 634, 68 159, 19 158, 12 158, 24 159, 13 -0.0921 0.123 0.455 0.3424 0.912 0.717 1.16 -0.351 0.375 0.35 0.4564 0.704 0.338 1.47 0.227 0.325 0.484 0.3151 1.26 0.664 2.37 -0.416 0.369 0.26 0.5851 0.66 0.32 1.36 PRS_PLINK_1e.04 528.41 Cyst of the salivary gland Both 43 394 10 digestive chartreuse4 394, 43 99, 12 98, 12 98, 13 99, 6 -0.173 0.163 0.287 0.5417 0.841 0.611 1.16 0.0891 0.426 0.834 0.07869 1.09 0.475 2.52 0.0659 0.424 0.876 0.05727 1.07 0.465 2.45 -0.803 0.503 0.111 0.9552 0.448 0.167 1.2 PRS_PLINK_1e.04 528.5 Diseases of lips Both 199 2156 10 digestive chartreuse4 2156, 199 539, 47 539, 47 539, 51 539, 54 0.0791 0.0744 0.288 0.5409 1.08 0.935 1.25 0.00174 0.212 0.993 0.002862 1 0.661 1.52 0.0848 0.208 0.683 0.1657 1.09 0.725 1.64 0.156 0.207 0.449 0.3478 1.17 0.78 1.75 PRS_PLINK_1e.04 528.6 Leukoplakia of oral mucosa Both 53 537 10 digestive chartreuse4 537, 53 135, 9 134, 16 134, 12 134, 16 0.214 0.151 0.156 0.8072 1.24 0.922 1.67 0.555 0.414 0.18 0.7444 1.74 0.774 3.92 0.259 0.429 0.546 0.2624 1.3 0.558 3.01 0.471 0.414 0.256 0.5919 1.6 0.711 3.61 PRS_PLINK_1e.04 528.7 Sialolithiasis Both 88 759 10 digestive chartreuse4 759, 88 190, 25 190, 24 189, 23 190, 16 -0.1 0.112 0.369 0.4324 0.904 0.726 1.13 -0.0722 0.303 0.811 0.09073 0.93 0.514 1.68 -0.0694 0.302 0.818 0.08707 0.933 0.516 1.69 -0.391 0.329 0.235 0.6295 0.677 0.355 1.29 PRS_PLINK_1e.04 529 Diseases and other conditions of the tongue Both 267 2935 10 digestive chartreuse4 2935, 267 734, 54 734, 79 733, 60 734, 74 0.0481 0.0634 0.448 0.349 1.05 0.927 1.19 0.37 0.182 0.0425 1.372 1.45 1.01 2.07 0.101 0.192 0.6 0.222 1.11 0.759 1.61 0.323 0.185 0.0805 1.094 1.38 0.962 1.99 PRS_PLINK_1e.04 529.1 Glossitis Both 50 580 10 digestive chartreuse4 580, 50 145, 14 145, 15 145, 10 145, 11 -0.135 0.145 0.35 0.4557 0.873 0.657 1.16 -0.0212 0.384 0.956 0.01955 0.979 0.462 2.08 -0.296 0.423 0.484 0.3148 0.744 0.325 1.7 -0.185 0.406 0.649 0.188 0.831 0.375 1.84 PRS_PLINK_1e.04 529.6 Glossodynia Both 67 673 10 digestive chartreuse4 673, 67 169, 13 168, 21 168, 17 168, 16 -0.00116 0.126 0.993 0.003188 0.999 0.78 1.28 0.428 0.359 0.234 0.6315 1.53 0.759 3.1 0.333 0.373 0.371 0.4302 1.4 0.672 2.9 0.223 0.376 0.554 0.2567 1.25 0.598 2.61 PRS_PLINK_1e.04 530 Diseases of esophagus Both 6239 16440 10 digestive chartreuse4 16440, 6239 4110, 1504 4110, 1558 4110, 1600 4110, 1576 0.0155 0.0152 0.308 0.5118 1.02 0.986 1.05 0.033 0.0432 0.445 0.3514 1.03 0.95 1.12 0.0558 0.043 0.194 0.7114 1.06 0.972 1.15 0.0355 0.0431 0.41 0.3874 1.04 0.952 1.13 PRS_PLINK_1e.04 530.1 Esophagitis, GERD and related diseases Both 6006 16440 10 digestive chartreuse4 16440, 6006 4110, 1458 4110, 1497 4110, 1537 4110, 1513 0.0143 0.0154 0.353 0.4526 1.01 0.984 1.05 0.025 0.0437 0.568 0.2456 1.03 0.941 1.12 0.0466 0.0436 0.285 0.5452 1.05 0.962 1.14 0.0263 0.0436 0.547 0.2622 1.03 0.943 1.12 PRS_PLINK_1e.04 530.11 GERD Both 5811 16438 10 digestive chartreuse4 16438, 5811 4110, 1410 4109, 1450 4109, 1477 4110, 1473 0.0147 0.0156 0.347 0.4603 1.01 0.984 1.05 0.0254 0.0443 0.565 0.2477 1.03 0.941 1.12 0.0386 0.0442 0.382 0.4179 1.04 0.953 1.13 0.0314 0.0441 0.476 0.3222 1.03 0.946 1.13 PRS_PLINK_1e.04 530.12 Ulcer of esophagus Both 92 1815 10 digestive chartreuse4 1815, 92 454, 28 454, 20 453, 19 454, 25 -0.0356 0.102 0.728 0.1381 0.965 0.79 1.18 -0.315 0.289 0.277 0.5579 0.73 0.414 1.29 -0.367 0.292 0.209 0.6797 0.693 0.391 1.23 -0.121 0.276 0.662 0.1795 0.886 0.516 1.52 PRS_PLINK_1e.04 530.13 Barrett's esophagus Both 224 3170 10 digestive chartreuse4 3170, 224 793, 55 792, 62 792, 61 793, 46 -0.0354 0.0679 0.602 0.2206 0.965 0.845 1.1 0.132 0.189 0.484 0.315 1.14 0.788 1.65 0.1 0.19 0.598 0.2235 1.11 0.762 1.6 -0.157 0.204 0.442 0.3549 0.855 0.574 1.27 PRS_PLINK_1e.04 530.14 Reflux esophagitis Both 617 8823 10 digestive chartreuse4 8823, 617 2206, 166 2206, 154 2205, 147 2206, 150 -0.0383 0.0413 0.354 0.4507 0.962 0.888 1.04 -0.0729 0.115 0.528 0.2773 0.93 0.741 1.17 -0.122 0.117 0.297 0.5279 0.885 0.705 1.11 -0.0994 0.116 0.391 0.4077 0.905 0.721 1.14 PRS_PLINK_1e.04 530.15 Eosinophilic esophagitis Both 137 1406 10 digestive chartreuse4 1406, 137 352, 35 351, 39 351, 39 352, 24 -0.0425 0.087 0.625 0.204 0.958 0.808 1.14 0.09 0.244 0.712 0.1472 1.09 0.678 1.77 0.119 0.241 0.621 0.2071 1.13 0.703 1.81 -0.359 0.271 0.186 0.731 0.699 0.411 1.19 PRS_PLINK_1e.04 530.2 Esophageal bleeding (varices/hemorrhage) Both 188 3025 10 digestive chartreuse4 3025, 188 757, 39 756, 57 756, 49 756, 43 0.017 0.0739 0.818 0.08746 1.02 0.88 1.18 0.375 0.21 0.0744 1.128 1.46 0.964 2.2 0.23 0.217 0.291 0.5368 1.26 0.822 1.93 0.0922 0.222 0.678 0.169 1.1 0.71 1.69 PRS_PLINK_1e.04 530.3 Stricture and stenosis of esophagus Both 315 4131 10 digestive chartreuse4 4131, 315 1033, 72 1033, 79 1032, 76 1033, 88 0.0752 0.0577 0.192 0.7162 1.08 0.963 1.21 0.0918 0.167 0.583 0.2346 1.1 0.79 1.52 0.0849 0.169 0.615 0.211 1.09 0.782 1.52 0.196 0.164 0.231 0.6368 1.22 0.883 1.68 PRS_PLINK_1e.04 530.5 Disorders of esophageal motility Both 187 2653 10 digestive chartreuse4 2653, 187 664, 45 663, 48 663, 47 663, 47 -0.0111 0.0748 0.882 0.05463 0.989 0.854 1.15 0.0548 0.211 0.795 0.09954 1.06 0.699 1.6 0.0602 0.212 0.776 0.1099 1.06 0.701 1.61 0.0387 0.212 0.855 0.06784 1.04 0.686 1.58 PRS_PLINK_1e.04 530.6 Diverticulum of esophagus, acquired Both 54 448 10 digestive chartreuse4 448, 54 112, 13 112, 14 112, 13 112, 14 -0.00485 0.136 0.971 0.01258 0.995 0.763 1.3 0.0908 0.394 0.818 0.08726 1.1 0.506 2.37 -0.0261 0.396 0.947 0.02349 0.974 0.448 2.12 0.0674 0.39 0.863 0.06402 1.07 0.498 2.3 PRS_PLINK_1e.04 530.7 Gastroesophageal laceration-hemorrhage syndrome Both 21 405 10 digestive chartreuse4 405, 21 102, 5 101, 7 101, 6 101, 3 -0.0338 0.194 0.862 0.06457 0.967 0.661 1.41 0.454 0.564 0.421 0.3762 1.57 0.522 4.75 0.425 0.576 0.461 0.3359 1.53 0.494 4.73 -0.386 0.657 0.557 0.254 0.68 0.188 2.47 PRS_PLINK_1e.04 530.9 Heartburn Both 554 8138 10 digestive chartreuse4 8138, 554 2035, 129 2034, 138 2034, 148 2035, 139 0.0435 0.044 0.323 0.4911 1.04 0.958 1.14 0.0793 0.126 0.528 0.2771 1.08 0.846 1.39 0.153 0.124 0.216 0.6654 1.17 0.914 1.49 0.0811 0.126 0.518 0.2854 1.08 0.848 1.39 PRS_PLINK_1e.04 531 Peptic ulcer (excl. esophageal) Both 630 8833 10 digestive chartreuse4 8833, 630 2209, 164 2208, 155 2208, 174 2208, 137 -0.0464 0.0409 0.256 0.591 0.955 0.881 1.03 -0.0546 0.115 0.636 0.1968 0.947 0.755 1.19 0.0573 0.113 0.611 0.2142 1.06 0.849 1.32 -0.18 0.119 0.13 0.8868 0.835 0.661 1.05 PRS_PLINK_1e.04 531.1 Hemorrhage from gastrointestinal ulcer Both 78 1460 10 digestive chartreuse4 1460, 78 365, 23 365, 26 365, 19 365, 10 -0.21 0.109 0.0532 1.274 0.811 0.655 1 0.117 0.286 0.682 0.1659 1.12 0.642 1.97 -0.191 0.309 0.537 0.27 0.826 0.451 1.51 -0.752 0.362 0.0376 1.425 0.471 0.232 0.958 PRS_PLINK_1e.04 531.2 Gastric ulcer Both 358 5179 10 digestive chartreuse4 5179, 358 1295, 98 1295, 89 1294, 90 1295, 81 -0.0631 0.054 0.243 0.6147 0.939 0.844 1.04 -0.0937 0.15 0.532 0.2738 0.911 0.679 1.22 -0.0873 0.15 0.561 0.2513 0.916 0.683 1.23 -0.185 0.153 0.229 0.6408 0.831 0.615 1.12 PRS_PLINK_1e.04 531.3 Duodenal ulcer Both 128 1795 10 digestive chartreuse4 1795, 128 449, 34 449, 36 448, 30 449, 28 -0.0809 0.0898 0.368 0.4345 0.922 0.773 1.1 0.091 0.242 0.707 0.1506 1.1 0.681 1.76 -0.11 0.254 0.665 0.1769 0.896 0.545 1.47 -0.173 0.258 0.502 0.2994 0.841 0.507 1.39 PRS_PLINK_1e.04 531.4 Peptic ulcer, site unspecified Both 226 3280 10 digestive chartreuse4 3280, 226 820, 57 820, 54 820, 71 820, 44 -0.0329 0.0692 0.635 0.1976 0.968 0.845 1.11 -0.0621 0.193 0.748 0.1261 0.94 0.643 1.37 0.229 0.183 0.211 0.6767 1.26 0.879 1.8 -0.268 0.204 0.188 0.7255 0.765 0.513 1.14 PRS_PLINK_1e.04 531.5 Gastrojejunal ulcer Both 49 740 10 digestive chartreuse4 740, 49 185, 11 185, 14 185, 15 185, 9 -0.0707 0.143 0.621 0.207 0.932 0.704 1.23 0.154 0.401 0.701 0.1544 1.17 0.532 2.56 0.21 0.393 0.593 0.2268 1.23 0.571 2.66 -0.187 0.427 0.661 0.18 0.829 0.359 1.91 PRS_PLINK_1e.04 532 Dysphagia Both 1965 15456 10 digestive chartreuse4 15456, 1965 3864, 467 3864, 505 3864, 511 3864, 482 0.0137 0.0241 0.568 0.2456 1.01 0.967 1.06 0.08 0.0686 0.244 0.6135 1.08 0.947 1.24 0.0865 0.0684 0.206 0.6854 1.09 0.953 1.25 0.0195 0.0693 0.779 0.1086 1.02 0.89 1.17 PRS_PLINK_1e.04 535 Gastritis and duodenitis Both 975 13262 10 digestive chartreuse4 13262, 975 3316, 264 3315, 245 3315, 252 3316, 214 -0.058 0.033 0.0785 1.105 0.944 0.885 1.01 -0.0718 0.0918 0.434 0.3624 0.931 0.777 1.11 -0.0498 0.0912 0.585 0.2329 0.951 0.796 1.14 -0.203 0.095 0.0323 1.491 0.816 0.677 0.983 PRS_PLINK_1e.04 535.1 Acute gastritis Both 383 5367 10 digestive chartreuse4 5367, 383 1342, 109 1342, 93 1341, 99 1342, 82 -0.11 0.0528 0.0376 1.425 0.896 0.808 0.994 -0.159 0.145 0.273 0.5631 0.853 0.642 1.13 -0.117 0.143 0.414 0.3825 0.89 0.672 1.18 -0.285 0.15 0.0567 1.246 0.752 0.56 1.01 PRS_PLINK_1e.04 535.2 Atrophic gastritis Both 124 1682 10 digestive chartreuse4 1682, 124 421, 32 420, 31 420, 31 421, 30 -0.00529 0.0921 0.954 0.02037 0.995 0.83 1.19 -0.0269 0.254 0.916 0.03822 0.973 0.591 1.6 -0.0188 0.255 0.941 0.02633 0.981 0.595 1.62 -0.078 0.257 0.762 0.1181 0.925 0.558 1.53 PRS_PLINK_1e.04 535.6 Duodenitis Both 96 1525 10 digestive chartreuse4 1525, 96 382, 30 381, 20 381, 20 381, 26 -0.0916 0.102 0.368 0.4338 0.912 0.747 1.11 -0.41 0.29 0.158 0.8009 0.664 0.376 1.17 -0.448 0.293 0.126 0.8994 0.639 0.359 1.13 -0.213 0.276 0.439 0.3573 0.808 0.47 1.39 PRS_PLINK_1e.04 535.8 Other specified gastritis Both 205 2960 10 digestive chartreuse4 2960, 205 740, 54 740, 58 740, 47 740, 46 -0.0411 0.0728 0.572 0.2425 0.96 0.832 1.11 0.0892 0.194 0.645 0.1904 1.09 0.748 1.6 -0.136 0.204 0.505 0.2966 0.873 0.586 1.3 -0.158 0.204 0.44 0.3565 0.854 0.572 1.27 PRS_PLINK_1e.04 535.9 Gastritis and duodenitis, NOS Both 451 6063 10 digestive chartreuse4 6063, 451 1516, 118 1516, 114 1515, 114 1516, 105 -0.0172 0.0487 0.724 0.1403 0.983 0.893 1.08 -0.0406 0.136 0.765 0.1164 0.96 0.736 1.25 -0.0483 0.135 0.721 0.142 0.953 0.731 1.24 -0.106 0.138 0.443 0.3535 0.899 0.686 1.18 PRS_PLINK_1e.04 536 Disorders of function of stomach Both 1092 13968 10 digestive chartreuse4 13968, 1092 3492, 269 3492, 246 3492, 294 3492, 282 0.00262 0.0314 0.934 0.02985 1 0.943 1.07 -0.0856 0.0912 0.348 0.4589 0.918 0.768 1.1 0.0885 0.0875 0.312 0.5064 1.09 0.92 1.3 0.055 0.0884 0.534 0.2724 1.06 0.888 1.26 PRS_PLINK_1e.04 536.3 Gastroparesis Both 193 3435 10 digestive chartreuse4 3435, 193 859, 52 859, 47 858, 50 859, 44 -0.0989 0.0738 0.18 0.7438 0.906 0.784 1.05 -0.0975 0.203 0.632 0.1995 0.907 0.609 1.35 -0.0532 0.2 0.79 0.1021 0.948 0.64 1.4 -0.148 0.207 0.473 0.3256 0.862 0.575 1.29 PRS_PLINK_1e.04 536.7 Complications of gastrostomy, colostomy and enterostomy Both 153 1877 10 digestive chartreuse4 1877, 153 470, 34 469, 46 469, 38 469, 35 0.00219 0.0842 0.979 0.009096 1 0.85 1.18 0.313 0.232 0.178 0.7505 1.37 0.868 2.16 0.114 0.241 0.638 0.1955 1.12 0.698 1.8 0.0359 0.245 0.884 0.05372 1.04 0.641 1.68 PRS_PLINK_1e.04 536.8 Dyspepsia and other specified disorders of function of stomach Both 839 10505 10 digestive chartreuse4 10505, 839 2627, 210 2626, 185 2626, 226 2626, 217 -0.00504 0.0358 0.888 0.05152 0.995 0.927 1.07 -0.127 0.104 0.221 0.6553 0.88 0.718 1.08 0.0749 0.0994 0.451 0.3454 1.08 0.887 1.31 0.0433 0.101 0.667 0.1761 1.04 0.857 1.27 PRS_PLINK_1e.04 537 Other disorders of stomach and duodenum Both 1037 14545 10 digestive chartreuse4 14545, 1037 3637, 251 3636, 274 3636, 250 3636, 262 0.0114 0.0322 0.723 0.1408 1.01 0.95 1.08 0.0901 0.0902 0.318 0.4978 1.09 0.917 1.31 -0.0064 0.0922 0.945 0.02473 0.994 0.829 1.19 0.044 0.0912 0.63 0.201 1.04 0.874 1.25 PRS_PLINK_1e.04 537.1 Lesions of stomach and duodenum Both 25 593 10 digestive chartreuse4 593, 25 149, 7 148, 6 148, 7 148, 5 -0.0751 0.196 0.701 0.1541 0.928 0.632 1.36 -0.183 0.513 0.722 0.1415 0.833 0.304 2.28 0.0178 0.487 0.971 0.01288 1.02 0.392 2.64 -0.324 0.529 0.54 0.2673 0.723 0.256 2.04 PRS_PLINK_1e.04 539 Bariatric surgery Both 508 8113 10 digestive chartreuse4 8113, 508 2029, 107 2028, 138 2028, 132 2028, 131 0.0499 0.0464 0.281 0.5506 1.05 0.96 1.15 0.241 0.132 0.0674 1.172 1.27 0.983 1.65 0.203 0.133 0.125 0.9017 1.23 0.945 1.59 0.193 0.133 0.148 0.8305 1.21 0.934 1.57 PRS_PLINK_1e.04 540 Appendiceal conditions Both 242 2783 10 digestive chartreuse4 2783, 242 696, 60 696, 52 695, 60 696, 70 0.132 0.0674 0.051 1.293 1.14 0.999 1.3 -0.131 0.194 0.5 0.3012 0.877 0.599 1.28 0.0119 0.188 0.949 0.02254 1.01 0.701 1.46 0.176 0.182 0.335 0.4755 1.19 0.834 1.7 PRS_PLINK_1e.04 540.1 Appendicitis Both 210 2403 10 digestive chartreuse4 2403, 210 601, 53 601, 42 600, 53 601, 62 0.12 0.0729 0.0989 1.005 1.13 0.978 1.3 -0.21 0.212 0.322 0.4921 0.811 0.535 1.23 0.00737 0.199 0.971 0.013 1.01 0.682 1.49 0.189 0.194 0.329 0.4831 1.21 0.826 1.77 PRS_PLINK_1e.04 540.11 Acute appendicitis Both 179 1987 10 digestive chartreuse4 1987, 179 497, 50 497, 33 496, 43 497, 53 0.0985 0.0793 0.214 0.6695 1.1 0.945 1.29 -0.407 0.23 0.0767 1.115 0.666 0.424 1.04 -0.139 0.214 0.516 0.2878 0.87 0.573 1.32 0.0734 0.205 0.72 0.1427 1.08 0.72 1.61 PRS_PLINK_1e.04 550 Abdominal hernia Both 2385 19008 10 digestive chartreuse4 19008, 2385 4751, 568 4752, 616 4752, 604 4752, 597 0.013 0.0218 0.553 0.2573 1.01 0.971 1.06 0.089 0.0621 0.152 0.8184 1.09 0.968 1.23 0.0617 0.0624 0.322 0.4917 1.06 0.941 1.2 0.0536 0.0625 0.39 0.4084 1.06 0.934 1.19 PRS_PLINK_1e.04 550.1 Inguinal hernia Both 689 6863 10 digestive chartreuse4 6863, 689 1716, 140 1716, 182 1715, 182 1716, 185 0.109 0.0399 0.0063 2.201 1.12 1.03 1.21 0.264 0.117 0.024 1.62 1.3 1.04 1.64 0.267 0.117 0.0226 1.646 1.31 1.04 1.64 0.292 0.117 0.0124 1.905 1.34 1.06 1.68 PRS_PLINK_1e.04 550.2 Diaphragmatic hernia Both 884 11250 10 digestive chartreuse4 11250, 884 2813, 208 2812, 240 2812, 226 2813, 210 -0.0246 0.035 0.482 0.3173 0.976 0.911 1.04 0.15 0.0982 0.127 0.8975 1.16 0.958 1.41 0.0754 0.0994 0.448 0.3484 1.08 0.887 1.31 0.00832 0.101 0.934 0.02949 1.01 0.827 1.23 PRS_PLINK_1e.04 550.3 Femoral hernia Both 61 595 10 digestive chartreuse4 595, 61 149, 15 149, 10 148, 14 149, 22 0.123 0.13 0.344 0.4637 1.13 0.877 1.46 -0.359 0.402 0.372 0.4289 0.698 0.317 1.54 -0.117 0.376 0.756 0.1213 0.89 0.425 1.86 0.411 0.349 0.24 0.6201 1.51 0.76 2.99 PRS_PLINK_1e.04 550.4 Umbilical hernia Both 467 6021 10 digestive chartreuse4 6021, 467 1506, 115 1505, 117 1505, 115 1505, 120 0.0118 0.0475 0.804 0.09501 1.01 0.922 1.11 0.0193 0.136 0.886 0.05232 1.02 0.782 1.33 0.0114 0.136 0.933 0.03018 1.01 0.775 1.32 0.0595 0.135 0.659 0.1814 1.06 0.815 1.38 PRS_PLINK_1e.04 550.5 Ventral hernia Both 737 9773 10 digestive chartreuse4 9773, 737 2444, 186 2443, 183 2443, 189 2443, 179 0.00598 0.0382 0.876 0.05765 1.01 0.933 1.08 -0.0236 0.108 0.826 0.08296 0.977 0.791 1.21 0.0126 0.107 0.906 0.0429 1.01 0.822 1.25 -0.037 0.108 0.732 0.1353 0.964 0.78 1.19 PRS_PLINK_1e.04 550.6 Incisional hernia Both 412 5770 10 digestive chartreuse4 5770, 412 1443, 88 1442, 113 1442, 108 1443, 103 0.0433 0.0514 0.399 0.3987 1.04 0.944 1.16 0.248 0.146 0.0883 1.054 1.28 0.963 1.71 0.194 0.147 0.188 0.7247 1.21 0.909 1.62 0.154 0.148 0.301 0.522 1.17 0.872 1.56 PRS_PLINK_1e.04 555 Inflammatory bowel disease and other gastroenteritis and colitis Both 777 8644 10 digestive chartreuse4 8644, 777 2161, 203 2161, 192 2161, 182 2161, 200 -0.00205 0.0377 0.957 0.01927 0.998 0.927 1.07 -0.0592 0.105 0.572 0.2424 0.943 0.767 1.16 -0.1 0.106 0.344 0.4629 0.904 0.734 1.11 -0.00284 0.104 0.978 0.009576 0.997 0.813 1.22 PRS_PLINK_1e.04 555.1 Regional enteritis Both 489 5400 10 digestive chartreuse4 5400, 489 1350, 120 1350, 123 1350, 121 1350, 125 0.0488 0.0472 0.301 0.5219 1.05 0.957 1.15 0.0312 0.134 0.815 0.08878 1.03 0.794 1.34 0.0217 0.134 0.872 0.05972 1.02 0.786 1.33 0.0618 0.133 0.643 0.1917 1.06 0.819 1.38 PRS_PLINK_1e.04 555.2 Ulcerative colitis Both 478 5262 10 digestive chartreuse4 5262, 478 1316, 127 1315, 128 1315, 104 1316, 119 -0.0461 0.0478 0.335 0.4752 0.955 0.869 1.05 0.00903 0.131 0.945 0.02463 1.01 0.781 1.3 -0.19 0.137 0.164 0.785 0.827 0.632 1.08 -0.0608 0.133 0.647 0.189 0.941 0.726 1.22 PRS_PLINK_1e.04 555.21 Ulcerative colitis (chronic) Both 290 3170 10 digestive chartreuse4 3170, 290 793, 76 792, 83 792, 63 793, 68 -0.0743 0.0614 0.226 0.6453 0.928 0.823 1.05 0.0789 0.166 0.634 0.1981 1.08 0.782 1.5 -0.189 0.176 0.282 0.5491 0.828 0.587 1.17 -0.114 0.173 0.51 0.2924 0.892 0.636 1.25 PRS_PLINK_1e.04 556 Ulceration of the lower GI tract Both 196 2783 10 digestive chartreuse4 2783, 196 696, 55 696, 52 695, 45 696, 44 -0.0586 0.0724 0.418 0.3784 0.943 0.818 1.09 -0.0251 0.198 0.899 0.04605 0.975 0.661 1.44 -0.173 0.206 0.4 0.3985 0.841 0.562 1.26 -0.197 0.207 0.341 0.4678 0.821 0.548 1.23 PRS_PLINK_1e.04 556.1 Ulceration of intestine Both 170 2429 10 digestive chartreuse4 2429, 170 608, 47 607, 45 607, 38 607, 40 -0.0443 0.0775 0.567 0.2462 0.957 0.822 1.11 -0.0437 0.213 0.838 0.07694 0.957 0.63 1.45 -0.179 0.223 0.423 0.3741 0.836 0.541 1.29 -0.125 0.22 0.57 0.2441 0.883 0.574 1.36 PRS_PLINK_1e.04 556.11 Angiodysplasia of intestine (without mention of hemorrhage) Both 29 657 10 digestive chartreuse4 657, 29 165, 7 164, 8 164, 4 164, 10 0.18 0.181 0.321 0.4941 1.2 0.839 1.71 0.218 0.485 0.653 0.1852 1.24 0.481 3.22 -0.336 0.552 0.543 0.2652 0.715 0.242 2.11 0.296 0.457 0.517 0.2868 1.35 0.549 3.3 PRS_PLINK_1e.04 557 Intestinal malabsorption (non-celiac) Both 768 9763 10 digestive chartreuse4 9763, 768 2441, 198 2441, 192 2440, 171 2441, 207 0.0046 0.0377 0.903 0.04429 1 0.933 1.08 -0.0323 0.105 0.758 0.1202 0.968 0.788 1.19 -0.148 0.108 0.169 0.7715 0.862 0.698 1.07 0.0444 0.103 0.667 0.176 1.05 0.854 1.28 PRS_PLINK_1e.04 557.1 Celiac disease Both 233 2365 10 digestive chartreuse4 2365, 233 592, 58 591, 65 591, 49 591, 61 -0.00326 0.0678 0.962 0.01701 0.997 0.873 1.14 0.111 0.188 0.554 0.2568 1.12 0.773 1.62 -0.165 0.201 0.411 0.3863 0.848 0.572 1.26 0.0532 0.19 0.78 0.1079 1.05 0.726 1.53 PRS_PLINK_1e.04 558 Noninfectious gastroenteritis Both 1409 14833 10 digestive chartreuse4 14833, 1409 3709, 361 3708, 325 3708, 370 3708, 353 0.0207 0.0279 0.46 0.3373 1.02 0.966 1.08 -0.109 0.0798 0.171 0.7664 0.897 0.767 1.05 0.0229 0.0776 0.768 0.1144 1.02 0.879 1.19 -0.0281 0.0785 0.721 0.1423 0.972 0.834 1.13 PRS_PLINK_1e.04 559 Ileostomy status Both 406 4709 10 digestive chartreuse4 4709, 406 1178, 89 1177, 108 1177, 110 1177, 99 0.0671 0.0515 0.193 0.7143 1.07 0.967 1.18 0.206 0.148 0.165 0.7817 1.23 0.919 1.64 0.219 0.148 0.139 0.8579 1.24 0.932 1.66 0.11 0.151 0.469 0.329 1.12 0.83 1.5 PRS_PLINK_1e.04 560 Intestinal obstruction without mention of hernia Both 1085 13004 10 digestive chartreuse4 13004, 1085 3251, 262 3251, 290 3251, 266 3251, 266 -0.00283 0.0315 0.928 0.0323 0.997 0.938 1.06 0.106 0.0887 0.233 0.6319 1.11 0.934 1.32 0.0199 0.0905 0.826 0.08323 1.02 0.854 1.22 0.0197 0.0904 0.828 0.08218 1.02 0.854 1.22 PRS_PLINK_1e.04 560.1 Paralytic ileus Both 520 7289 10 digestive chartreuse4 7289, 520 1823, 134 1822, 140 1822, 124 1822, 121 -0.049 0.0449 0.276 0.5596 0.952 0.872 1.04 0.0443 0.125 0.722 0.1412 1.05 0.819 1.33 -0.0769 0.128 0.549 0.2603 0.926 0.72 1.19 -0.106 0.129 0.41 0.3873 0.899 0.699 1.16 PRS_PLINK_1e.04 560.2 Impaction of intestine Both 149 1974 10 digestive chartreuse4 1974, 149 494, 36 493, 42 493, 41 494, 30 -0.00932 0.0857 0.913 0.03937 0.991 0.838 1.17 0.116 0.232 0.616 0.2107 1.12 0.713 1.77 0.163 0.233 0.483 0.3163 1.18 0.746 1.86 -0.141 0.249 0.572 0.2423 0.869 0.533 1.42 PRS_PLINK_1e.04 560.3 Peritoneal or intestinal adhesions Both 87 1258 10 digestive chartreuse4 1258, 87 315, 22 314, 19 314, 24 315, 22 0.0447 0.113 0.692 0.1598 1.05 0.838 1.3 -0.193 0.313 0.537 0.2697 0.824 0.446 1.52 0.0519 0.302 0.863 0.0638 1.05 0.583 1.9 0.0312 0.302 0.918 0.03733 1.03 0.571 1.87 PRS_PLINK_1e.04 560.4 Other intestinal obstruction Both 628 8190 10 digestive chartreuse4 8190, 628 2048, 146 2047, 158 2047, 163 2048, 161 0.0326 0.0416 0.433 0.3631 1.03 0.952 1.12 0.0748 0.118 0.528 0.2773 1.08 0.854 1.36 0.116 0.118 0.324 0.4895 1.12 0.892 1.41 0.108 0.118 0.359 0.4451 1.11 0.884 1.4 PRS_PLINK_1e.04 561 Symptoms involving digestive system Both 1047 11790 10 digestive chartreuse4 11790, 1047 2948, 280 2947, 234 2947, 283 2948, 249 -0.0352 0.0321 0.273 0.5645 0.965 0.907 1.03 -0.176 0.0922 0.056 1.251 0.839 0.7 1 0.0049 0.0881 0.956 0.01969 1 0.846 1.19 -0.117 0.0908 0.196 0.7086 0.889 0.744 1.06 PRS_PLINK_1e.04 562 Diverticulosis and diverticulitis Both 1746 11479 10 digestive chartreuse4 11479, 1746 2870, 453 2870, 457 2869, 419 2870, 417 -0.0399 0.026 0.125 0.9033 0.961 0.913 1.01 -0.00754 0.073 0.918 0.03728 0.992 0.86 1.15 -0.1 0.0741 0.176 0.754 0.905 0.782 1.05 -0.102 0.0741 0.169 0.7732 0.903 0.781 1.04 PRS_PLINK_1e.04 562.1 Diverticulosis Both 1733 11440 10 digestive chartreuse4 11440, 1733 2860, 450 2860, 451 2860, 420 2860, 412 -0.0406 0.0261 0.12 0.9217 0.96 0.912 1.01 -0.013 0.0733 0.859 0.06577 0.987 0.855 1.14 -0.0922 0.0742 0.214 0.6696 0.912 0.788 1.05 -0.108 0.0745 0.146 0.8362 0.897 0.775 1.04 PRS_PLINK_1e.04 562.2 Diverticulitis Both 449 6589 10 digestive chartreuse4 6589, 449 1648, 109 1647, 123 1647, 96 1647, 121 0.0337 0.0486 0.489 0.3109 1.03 0.94 1.14 0.116 0.135 0.392 0.4071 1.12 0.862 1.46 -0.126 0.143 0.379 0.4213 0.882 0.666 1.17 0.101 0.136 0.458 0.3393 1.11 0.848 1.44 PRS_PLINK_1e.04 564 Functional digestive disorders Both 4660 16176 10 digestive chartreuse4 16176, 4660 4044, 1142 4044, 1180 4044, 1211 4044, 1126 -0.0102 0.0169 0.546 0.2627 0.99 0.958 1.02 0.0282 0.0477 0.554 0.2564 1.03 0.937 1.13 0.0473 0.0475 0.319 0.496 1.05 0.955 1.15 -0.0299 0.0482 0.534 0.2724 0.971 0.883 1.07 PRS_PLINK_1e.04 564.1 Irritable Bowel Syndrome Both 1614 12760 10 digestive chartreuse4 12760, 1614 3190, 405 3190, 387 3190, 413 3190, 409 -0.000577 0.0266 0.983 0.00759 0.999 0.949 1.05 -0.047 0.0755 0.533 0.2729 0.954 0.823 1.11 0.0204 0.0745 0.784 0.1054 1.02 0.882 1.18 -0.00348 0.0748 0.963 0.0164 0.997 0.861 1.15 PRS_PLINK_1e.04 564.9 Personal history of diseases of digestive system Both 1169 13824 10 digestive chartreuse4 13824, 1169 3456, 302 3456, 297 3456, 290 3456, 280 -0.0354 0.0302 0.242 0.6164 0.965 0.91 1.02 -0.0151 0.085 0.859 0.0662 0.985 0.834 1.16 -0.0358 0.0855 0.675 0.1704 0.965 0.816 1.14 -0.0681 0.0863 0.43 0.3667 0.934 0.789 1.11 PRS_PLINK_1e.04 565 Anal and rectal conditions Both 1374 15363 10 digestive chartreuse4 15363, 1374 3840, 363 3841, 343 3840, 348 3841, 320 -0.0454 0.0279 0.104 0.982 0.956 0.905 1.01 -0.0624 0.0785 0.427 0.3696 0.94 0.805 1.1 -0.0457 0.0783 0.559 0.2525 0.955 0.819 1.11 -0.129 0.0799 0.105 0.9776 0.879 0.751 1.03 PRS_PLINK_1e.04 565.1 Anal and rectal polyp Both 404 5049 10 digestive chartreuse4 5049, 404 1263, 118 1262, 92 1262, 102 1262, 92 -0.076 0.0509 0.135 0.869 0.927 0.839 1.02 -0.26 0.144 0.0705 1.152 0.771 0.582 1.02 -0.151 0.14 0.279 0.555 0.859 0.654 1.13 -0.264 0.144 0.0668 1.175 0.768 0.579 1.02 PRS_PLINK_1e.04 567 Peritonitis and retroperitoneal infections Both 456 6556 10 digestive chartreuse4 6556, 456 1639, 135 1639, 95 1639, 119 1639, 107 -0.0332 0.0479 0.488 0.3115 0.967 0.881 1.06 -0.347 0.138 0.0116 1.936 0.707 0.54 0.925 -0.121 0.13 0.35 0.4556 0.886 0.687 1.14 -0.236 0.133 0.0762 1.118 0.789 0.608 1.03 PRS_PLINK_1e.04 568 Other disorders of peritoneum Both 564 8056 10 digestive chartreuse4 8056, 564 2014, 144 2014, 136 2014, 153 2014, 131 -0.0422 0.0436 0.333 0.4776 0.959 0.88 1.04 -0.0544 0.123 0.659 0.1814 0.947 0.744 1.21 0.0642 0.12 0.592 0.2277 1.07 0.843 1.35 -0.0913 0.124 0.462 0.3355 0.913 0.716 1.16 PRS_PLINK_1e.04 568.1 Peritoneal adhesions (postoperative) (postinfection) Both 432 5858 10 digestive chartreuse4 5858, 432 1465, 111 1464, 109 1464, 111 1465, 101 -0.0626 0.0494 0.205 0.6872 0.939 0.853 1.03 -0.0214 0.139 0.878 0.0567 0.979 0.745 1.29 0.00386 0.138 0.978 0.009786 1 0.766 1.32 -0.0943 0.141 0.505 0.297 0.91 0.69 1.2 PRS_PLINK_1e.04 569 Other disorders of intestine Both 2859 18737 10 digestive chartreuse4 18737, 2859 4684, 739 4684, 727 4684, 706 4684, 687 -0.0251 0.0202 0.215 0.6677 0.975 0.937 1.01 -0.019 0.0567 0.738 0.1322 0.981 0.878 1.1 -0.0488 0.0571 0.392 0.4062 0.952 0.852 1.07 -0.0855 0.0574 0.136 0.8651 0.918 0.82 1.03 PRS_PLINK_1e.04 569.1 Toxic gastroenteritis and colitis Both 97 1544 10 digestive chartreuse4 1544, 97 386, 28 386, 22 386, 25 386, 22 -0.097 0.102 0.344 0.464 0.908 0.742 1.11 -0.244 0.285 0.391 0.4082 0.783 0.448 1.37 -0.0936 0.28 0.738 0.1317 0.911 0.526 1.58 -0.256 0.287 0.371 0.4307 0.774 0.441 1.36 PRS_PLINK_1e.04 569.2 Gastrointestinal complications Both 513 6970 10 digestive chartreuse4 6970, 513 1742, 124 1742, 143 1742, 124 1743, 122 -0.00758 0.0458 0.868 0.06127 0.992 0.907 1.09 0.142 0.127 0.261 0.5839 1.15 0.9 1.48 0.00213 0.131 0.987 0.005679 1 0.776 1.29 -0.00245 0.131 0.985 0.006503 0.998 0.771 1.29 PRS_PLINK_1e.04 571 Chronic liver disease and cirrhosis Both 1362 16965 10 digestive chartreuse4 16965, 1362 4241, 345 4241, 344 4241, 345 4241, 328 -0.0201 0.0281 0.474 0.324 0.98 0.928 1.04 0.000205 0.0792 0.998 0.0008971 1 0.856 1.17 0.00154 0.0793 0.985 0.006763 1 0.857 1.17 -0.0423 0.0802 0.598 0.2234 0.959 0.819 1.12 PRS_PLINK_1e.04 571.5 Other chronic nonalcoholic liver disease Both 1292 16720 10 digestive chartreuse4 16720, 1292 4179, 326 4180, 331 4180, 327 4180, 308 -0.0211 0.0287 0.463 0.3346 0.979 0.925 1.04 0.0176 0.081 0.828 0.08176 1.02 0.868 1.19 0.00468 0.0813 0.954 0.02041 1 0.857 1.18 -0.0474 0.0825 0.565 0.2477 0.954 0.811 1.12 PRS_PLINK_1e.04 571.51 Cirrhosis of liver without mention of alcohol Both 224 4552 10 digestive chartreuse4 4552, 224 1138, 48 1138, 66 1138, 54 1138, 56 0.0438 0.0682 0.52 0.2837 1.04 0.914 1.19 0.312 0.191 0.103 0.9862 1.37 0.939 1.99 0.114 0.199 0.568 0.2454 1.12 0.759 1.65 0.141 0.197 0.476 0.3221 1.15 0.782 1.7 PRS_PLINK_1e.04 571.6 Primary biliary cirrhosis Both 62 874 10 digestive chartreuse4 874, 62 219, 10 218, 19 218, 16 219, 17 0.187 0.133 0.159 0.7979 1.21 0.929 1.56 0.674 0.388 0.0823 1.085 1.96 0.917 4.2 0.365 0.391 0.35 0.4553 1.44 0.67 3.1 0.529 0.389 0.173 0.7609 1.7 0.792 3.64 PRS_PLINK_1e.04 571.8 Liver abscess and sequelae of chronic liver disease Both 227 4258 10 digestive chartreuse4 4258, 227 1065, 55 1064, 60 1064, 55 1065, 57 -0.00129 0.0681 0.985 0.0066 0.999 0.874 1.14 0.0813 0.189 0.666 0.1762 1.08 0.749 1.57 -0.0181 0.193 0.925 0.03373 0.982 0.673 1.43 0.0205 0.191 0.915 0.03881 1.02 0.702 1.48 PRS_PLINK_1e.04 571.81 Portal hypertension Both 134 2547 10 digestive chartreuse4 2547, 134 637, 30 637, 41 636, 31 637, 32 0.0193 0.0859 0.822 0.08493 1.02 0.861 1.21 0.316 0.242 0.19 0.7203 1.37 0.855 2.2 0.0445 0.255 0.861 0.06485 1.05 0.634 1.72 0.0508 0.254 0.842 0.07481 1.05 0.639 1.73 PRS_PLINK_1e.04 572 Ascites (non malignant) Both 707 11032 10 digestive chartreuse4 11032, 707 2758, 168 2758, 191 2758, 191 2758, 157 -0.0315 0.0387 0.416 0.3807 0.969 0.898 1.05 0.129 0.109 0.234 0.6307 1.14 0.92 1.41 0.132 0.109 0.226 0.6462 1.14 0.922 1.41 -0.0599 0.114 0.598 0.2231 0.942 0.754 1.18 PRS_PLINK_1e.04 573 Other disorders of liver Both 1837 17771 10 digestive chartreuse4 17771, 1837 4442, 456 4443, 434 4442, 467 4443, 480 0.0147 0.0246 0.55 0.2598 1.01 0.967 1.06 -0.0492 0.0705 0.485 0.3138 0.952 0.829 1.09 0.0208 0.0695 0.765 0.1166 1.02 0.891 1.17 0.0519 0.0691 0.453 0.3438 1.05 0.92 1.21 PRS_PLINK_1e.04 573.1 Chronic passive congestion of liver Both 12 648 10 digestive chartreuse4 648, 12 162, 6 162, 4 162, 0 162, 2 -0.542 0.244 0.0263 1.58 0.582 0.361 0.938 -0.456 0.562 0.417 0.3795 0.634 0.211 1.91 -2.54 1.16 0.0284 1.547 0.0792 0.0082 0.765 -1.05 0.672 0.117 0.9305 0.349 0.0937 1.3 PRS_PLINK_1e.04 573.2 Liver replaced by transplant Both 37 1379 10 digestive chartreuse4 1379, 37 345, 8 345, 19 344, 6 345, 4 -0.204 0.151 0.176 0.7537 0.816 0.607 1.1 0.817 0.401 0.0414 1.383 2.26 1.03 4.96 -0.369 0.481 0.443 0.354 0.691 0.269 1.77 -0.589 0.526 0.262 0.5811 0.555 0.198 1.55 PRS_PLINK_1e.04 573.3 Hepatomegaly Both 150 2446 10 digestive chartreuse4 2446, 150 612, 43 611, 39 611, 30 612, 38 -0.0341 0.0835 0.683 0.1653 0.967 0.821 1.14 -0.104 0.223 0.641 0.1934 0.901 0.582 1.4 -0.342 0.239 0.152 0.8194 0.71 0.445 1.13 -0.121 0.226 0.592 0.2275 0.886 0.569 1.38 PRS_PLINK_1e.04 573.4 Acute and subacute necrosis of liver Both 70 1528 10 digestive chartreuse4 1528, 70 382, 19 382, 16 382, 16 382, 19 -0.0789 0.122 0.516 0.2872 0.924 0.728 1.17 -0.176 0.329 0.592 0.2277 0.838 0.44 1.6 -0.175 0.329 0.595 0.2257 0.839 0.441 1.6 -0.057 0.318 0.858 0.0666 0.945 0.507 1.76 PRS_PLINK_1e.04 573.5 Jaundice (not of newborn) Both 346 4433 10 digestive chartreuse4 4433, 346 1108, 89 1108, 88 1108, 80 1108, 89 -0.0384 0.0555 0.489 0.3104 0.962 0.863 1.07 -0.00951 0.155 0.951 0.02174 0.991 0.731 1.34 -0.098 0.159 0.537 0.27 0.907 0.664 1.24 0.0137 0.155 0.93 0.03163 1.01 0.748 1.37 PRS_PLINK_1e.04 573.6 Nonspecific elevation of levels of transaminase or lactic acid dehydrogenase [LDH] Both 851 13171 10 digestive chartreuse4 13171, 851 3292, 212 3293, 235 3292, 202 3293, 202 -0.0264 0.0351 0.453 0.3441 0.974 0.909 1.04 0.113 0.0976 0.248 0.6055 1.12 0.924 1.36 -0.0366 0.101 0.717 0.1443 0.964 0.791 1.18 -0.0317 0.101 0.755 0.1223 0.969 0.794 1.18 PRS_PLINK_1e.04 573.7 Abnormal results of function study of liver Both 952 13754 10 digestive chartreuse4 13754, 952 3438, 221 3438, 230 3438, 268 3439, 233 0.0216 0.0335 0.518 0.2856 1.02 0.957 1.09 0.0433 0.0969 0.655 0.1834 1.04 0.864 1.26 0.197 0.0939 0.0361 1.442 1.22 1.01 1.46 0.0653 0.0969 0.501 0.3003 1.07 0.883 1.29 PRS_PLINK_1e.04 573.9 Abnormal serum enzyme levels Both 1513 18011 10 digestive chartreuse4 18011, 1513 4502, 376 4503, 359 4502, 390 4503, 388 0.0128 0.0268 0.634 0.1976 1.01 0.961 1.07 -0.0406 0.0768 0.597 0.2239 0.96 0.826 1.12 0.0444 0.0755 0.556 0.2548 1.05 0.902 1.21 0.0414 0.0756 0.584 0.2332 1.04 0.899 1.21 PRS_PLINK_1e.04 574 Cholelithiasis and cholecystitis Both 1153 14934 10 digestive chartreuse4 14934, 1153 3733, 281 3733, 303 3733, 277 3734, 292 0.00585 0.0307 0.849 0.07118 1.01 0.947 1.07 0.072 0.0858 0.401 0.3965 1.07 0.908 1.27 -0.0186 0.0875 0.832 0.07991 0.982 0.827 1.17 0.0366 0.0865 0.672 0.1726 1.04 0.876 1.23 PRS_PLINK_1e.04 574.1 Cholelithiasis Both 1073 14039 10 digestive chartreuse4 14039, 1073 3509, 263 3510, 284 3509, 265 3510, 261 -0.011 0.0318 0.729 0.1373 0.989 0.929 1.05 0.07 0.0886 0.429 0.3673 1.07 0.902 1.28 0.00304 0.09 0.973 0.01188 1 0.841 1.2 -0.0094 0.0903 0.917 0.0376 0.991 0.83 1.18 PRS_PLINK_1e.04 574.11 Cholelithiasis with acute cholecystitis Both 124 1571 10 digestive chartreuse4 1571, 124 393, 30 393, 27 392, 40 393, 27 0.013 0.0949 0.891 0.05009 1.01 0.841 1.22 -0.0988 0.268 0.712 0.1476 0.906 0.536 1.53 0.276 0.247 0.263 0.5793 1.32 0.812 2.14 -0.134 0.269 0.618 0.2089 0.875 0.517 1.48 PRS_PLINK_1e.04 574.12 Cholelithiasis with other cholecystitis Both 213 2743 10 digestive chartreuse4 2743, 213 686, 53 686, 53 685, 51 686, 56 0.000442 0.072 0.995 0.002129 1 0.869 1.15 -0.00844 0.198 0.966 0.01499 0.992 0.672 1.46 -0.0654 0.201 0.745 0.1276 0.937 0.631 1.39 0.0402 0.197 0.838 0.07664 1.04 0.708 1.53 PRS_PLINK_1e.04 574.2 Calculus of bile duct Both 319 4195 10 digestive chartreuse4 4195, 319 1048, 80 1049, 82 1048, 84 1049, 73 -0.00305 0.0589 0.959 0.0183 0.997 0.888 1.12 0.0306 0.161 0.85 0.07067 1.03 0.751 1.41 0.0487 0.161 0.762 0.1182 1.05 0.766 1.44 -0.0791 0.166 0.634 0.1977 0.924 0.667 1.28 PRS_PLINK_1e.04 574.3 Cholecystitis without cholelithiasis Both 285 3834 10 digestive chartreuse4 3834, 285 958, 62 958, 73 958, 67 959, 83 0.0775 0.062 0.211 0.6759 1.08 0.957 1.22 0.182 0.176 0.302 0.5207 1.2 0.849 1.7 0.0907 0.18 0.614 0.212 1.09 0.77 1.56 0.295 0.172 0.0868 1.061 1.34 0.958 1.88 PRS_PLINK_1e.04 575 Other biliary tract disease Both 817 10798 10 digestive chartreuse4 10798, 817 2699, 218 2699, 189 2699, 214 2700, 196 -0.0357 0.0361 0.323 0.4908 0.965 0.899 1.04 -0.148 0.103 0.15 0.8226 0.863 0.706 1.06 -0.0154 0.0997 0.877 0.05686 0.985 0.81 1.2 -0.106 0.102 0.299 0.5238 0.9 0.737 1.1 PRS_PLINK_1e.04 575.1 Cholangitis Both 123 1513 10 digestive chartreuse4 1513, 123 379, 28 378, 37 378, 30 378, 28 0.0115 0.0939 0.903 0.0444 1.01 0.841 1.22 0.303 0.257 0.239 0.6223 1.35 0.818 2.24 0.103 0.267 0.7 0.1547 1.11 0.657 1.87 0.0769 0.273 0.778 0.1089 1.08 0.633 1.84 PRS_PLINK_1e.04 575.2 Obstruction of bile duct Both 214 2686 10 digestive chartreuse4 2686, 214 672, 55 671, 55 671, 53 672, 51 -0.00377 0.0711 0.958 0.01878 0.996 0.867 1.15 0.00332 0.196 0.986 0.005916 1 0.684 1.47 -0.0361 0.197 0.855 0.06801 0.965 0.655 1.42 -0.0499 0.201 0.804 0.09498 0.951 0.642 1.41 PRS_PLINK_1e.04 575.6 Cholesterolosis of gallbladder Both 113 1169 10 digestive chartreuse4 1169, 113 293, 35 292, 20 292, 31 292, 27 -0.157 0.0948 0.0988 1.005 0.855 0.71 1.03 -0.53 0.284 0.0618 1.209 0.589 0.338 1.03 -0.121 0.255 0.635 0.1974 0.886 0.537 1.46 -0.329 0.268 0.219 0.6595 0.72 0.426 1.22 PRS_PLINK_1e.04 575.7 Other disorders of gallbladder Both 326 4627 10 digestive chartreuse4 4627, 326 1156, 87 1157, 81 1156, 81 1157, 77 -0.0432 0.0571 0.449 0.3479 0.958 0.856 1.07 -0.0721 0.158 0.649 0.188 0.93 0.682 1.27 -0.0644 0.158 0.684 0.1648 0.938 0.688 1.28 -0.126 0.16 0.431 0.366 0.881 0.644 1.21 PRS_PLINK_1e.04 575.8 Other disorders of biliary tract Both 399 5220 10 digestive chartreuse4 5220, 399 1305, 96 1305, 96 1305, 112 1305, 95 0.0202 0.0517 0.696 0.1575 1.02 0.922 1.13 -0.00327 0.148 0.982 0.007706 0.997 0.745 1.33 0.154 0.143 0.282 0.5496 1.17 0.881 1.55 -0.00795 0.149 0.957 0.01894 0.992 0.741 1.33 PRS_PLINK_1e.04 575.9 Nonspecific abnormal findings on radiological and other examination of biliary tract Both 77 1167 10 digestive chartreuse4 1167, 77 292, 22 292, 19 291, 20 292, 16 0.00786 0.113 0.944 0.02482 1.01 0.808 1.26 -0.157 0.314 0.617 0.2096 0.855 0.462 1.58 -0.0462 0.312 0.882 0.05444 0.955 0.518 1.76 -0.287 0.324 0.376 0.4251 0.751 0.398 1.42 PRS_PLINK_1e.04 577 Diseases of pancreas Both 716 9505 10 digestive chartreuse4 9505, 716 2377, 196 2376, 159 2376, 180 2376, 181 -0.0163 0.0389 0.675 0.1708 0.984 0.912 1.06 -0.21 0.11 0.0571 1.243 0.811 0.653 1.01 -0.0946 0.107 0.377 0.4239 0.91 0.738 1.12 -0.0804 0.107 0.451 0.3454 0.923 0.749 1.14 PRS_PLINK_1e.04 577.1 Acute pancreatitis Both 404 5547 10 digestive chartreuse4 5547, 404 1387, 111 1387, 86 1386, 111 1387, 96 -0.0254 0.0518 0.625 0.2044 0.975 0.881 1.08 -0.249 0.147 0.0905 1.043 0.78 0.584 1.04 0.00531 0.139 0.969 0.01346 1.01 0.766 1.32 -0.14 0.143 0.327 0.4851 0.869 0.656 1.15 PRS_PLINK_1e.04 577.2 Chronic pancreatitis Both 157 2225 10 digestive chartreuse4 2225, 157 557, 43 556, 36 556, 46 556, 32 -0.0347 0.0842 0.68 0.1674 0.966 0.819 1.14 -0.17 0.228 0.457 0.3404 0.844 0.54 1.32 0.0849 0.217 0.696 0.1576 1.09 0.711 1.67 -0.305 0.236 0.196 0.7072 0.737 0.464 1.17 PRS_PLINK_1e.04 577.3 Cyst and pseudocyst of pancreas Both 180 2069 10 digestive chartreuse4 2069, 180 518, 48 517, 36 517, 56 517, 40 -0.0342 0.0755 0.65 0.1869 0.966 0.833 1.12 -0.267 0.224 0.234 0.6302 0.766 0.494 1.19 0.155 0.204 0.448 0.3485 1.17 0.783 1.74 -0.157 0.22 0.476 0.3226 0.855 0.556 1.31 PRS_PLINK_1e.04 578 Gastrointestinal hemorrhage Both 1609 19236 10 digestive chartreuse4 19236, 1609 4809, 403 4809, 394 4809, 428 4809, 383 -0.0195 0.026 0.453 0.3444 0.981 0.932 1.03 -0.0218 0.0737 0.768 0.1148 0.978 0.847 1.13 0.0551 0.0723 0.446 0.3506 1.06 0.917 1.22 -0.0488 0.0742 0.511 0.2916 0.952 0.824 1.1 PRS_PLINK_1e.04 578.1 Hematemesis Both 139 2409 10 digestive chartreuse4 2409, 139 603, 34 602, 34 602, 44 602, 27 -0.0261 0.0846 0.758 0.1205 0.974 0.825 1.15 -0.0224 0.243 0.926 0.03316 0.978 0.608 1.57 0.246 0.23 0.286 0.5432 1.28 0.814 2.01 -0.219 0.257 0.392 0.4062 0.803 0.486 1.33 PRS_PLINK_1e.04 578.2 Blood in stool Both 913 12756 10 digestive chartreuse4 12756, 913 3189, 227 3189, 211 3189, 262 3189, 213 -0.0119 0.0342 0.728 0.138 0.988 0.924 1.06 -0.0678 0.0986 0.492 0.3082 0.934 0.77 1.13 0.144 0.0939 0.125 0.9024 1.15 0.961 1.39 -0.0596 0.0984 0.545 0.2638 0.942 0.777 1.14 PRS_PLINK_1e.04 578.8 Hemorrhage of rectum and anus Both 876 11148 10 digestive chartreuse4 11148, 876 2787, 220 2787, 218 2787, 225 2787, 212 -0.0295 0.0349 0.397 0.4007 0.971 0.907 1.04 -0.00822 0.0989 0.934 0.02976 0.992 0.817 1.2 0.0191 0.0985 0.846 0.07245 1.02 0.84 1.24 -0.0298 0.0998 0.765 0.1162 0.971 0.798 1.18 PRS_PLINK_1e.04 578.9 Hemorrhage of gastrointestinal tract Both 355 6592 10 digestive chartreuse4 6592, 355 1648, 97 1648, 97 1648, 83 1648, 78 -0.0918 0.0538 0.0879 1.056 0.912 0.821 1.01 -0.00717 0.147 0.961 0.01729 0.993 0.745 1.32 -0.145 0.152 0.341 0.4668 0.865 0.642 1.17 -0.217 0.155 0.16 0.7971 0.805 0.594 1.09 PRS_PLINK_1e.04 579 Other symptoms involving abdomen and pelvis Both 1603 17573 10 digestive chartreuse4 17573, 1603 4394, 372 4393, 395 4393, 423 4393, 412 0.0255 0.0263 0.332 0.479 1.03 0.974 1.08 0.0557 0.0755 0.461 0.3365 1.06 0.912 1.23 0.127 0.0743 0.0866 1.062 1.14 0.982 1.31 0.102 0.0747 0.171 0.7665 1.11 0.957 1.28 PRS_PLINK_1e.04 579.2 Splenomegaly Both 200 3675 10 digestive chartreuse4 3675, 200 919, 42 919, 56 918, 58 919, 44 -0.0278 0.0736 0.705 0.1516 0.973 0.842 1.12 0.284 0.205 0.166 0.7786 1.33 0.888 1.99 0.394 0.206 0.0555 1.256 1.48 0.991 2.22 0.0727 0.218 0.739 0.1315 1.08 0.702 1.65 PRS_PLINK_1e.04 579.8 Nonspecific abnormal findings in stool contents Both 434 6057 10 digestive chartreuse4 6057, 434 1515, 98 1514, 111 1514, 118 1514, 107 0.0214 0.0499 0.668 0.1749 1.02 0.926 1.13 0.126 0.143 0.377 0.424 1.13 0.858 1.5 0.174 0.141 0.216 0.6658 1.19 0.903 1.57 0.0821 0.144 0.567 0.2461 1.09 0.819 1.44 PRS_PLINK_1e.04 580 Nephritis; nephrosis; renal sclerosis Both 218 7712 11 genitourinary black 7712, 218 1928, 53 1928, 57 1928, 55 1928, 53 0.0477 0.0686 0.487 0.3125 1.05 0.917 1.2 0.0714 0.19 0.708 0.1502 1.07 0.739 1.56 0.0409 0.191 0.831 0.0806 1.04 0.716 1.51 0.0167 0.194 0.932 0.03079 1.02 0.695 1.49 PRS_PLINK_1e.04 580.1 Glomerulonephritis Both 22 2042 11 genitourinary black 2042, 22 511, 8 510, 4 510, 5 511, 5 -0.0951 0.198 0.631 0.1998 0.909 0.617 1.34 -0.608 0.521 0.244 0.6135 0.545 0.196 1.51 -0.474 0.495 0.338 0.4707 0.623 0.236 1.64 -0.421 0.498 0.397 0.4008 0.656 0.247 1.74 PRS_PLINK_1e.04 580.11 Proliferative glomerulonephritis Both 4 804 11 genitourinary black 804, 4 201, 2 201, 0 201, 2 201, 0 -0.455 0.335 0.174 0.759 0.635 0.329 1.22 -1.85 1.12 0.0991 1.004 0.157 0.0174 1.42 0.086 0.761 0.91 0.04093 1.09 0.245 4.84 -2.67 1.33 0.0446 1.351 0.0691 0.0051 0.937 PRS_PLINK_1e.04 580.12 Non-proliferative glomerulonephritis Both 4 621 11 genitourinary black 621, 4 156, 3 155, 0 155, 0 155, 1 -0.507 0.337 0.132 0.8804 0.602 0.311 1.16 -1.93 1.15 0.0925 1.034 0.145 0.0154 1.37 -1.45 1.06 0.173 0.7624 0.235 0.0294 1.88 -0.56 0.808 0.488 0.3112 0.571 0.117 2.79 PRS_PLINK_1e.04 580.13 Acute glomerulonephritis, NOS Both 6 308 11 genitourinary black 308, 6 77, 1 77, 0 77, 3 77, 2 0.783 0.36 0.0295 1.53 2.19 1.08 4.43 -0.27 1.09 0.804 0.0948 0.763 0.0903 6.45 1.31 0.921 0.155 0.8095 3.71 0.609 22.6 0.616 0.831 0.459 0.3382 1.85 0.363 9.44 PRS_PLINK_1e.04 580.14 Chronic glomerulonephritis, NOS Both 11 1403 11 genitourinary black 1403, 11 351, 4 351, 4 350, 2 351, 1 -0.446 0.245 0.0688 1.162 0.64 0.396 1.04 -0.0157 0.584 0.979 0.009427 0.984 0.313 3.09 -0.845 0.689 0.22 0.6581 0.429 0.111 1.66 -1.17 0.755 0.12 0.9207 0.309 0.0704 1.36 PRS_PLINK_1e.04 580.2 Nephrotic syndrome without mention of glomerulonephritis Both 20 1186 11 genitourinary black 1186, 20 297, 9 296, 4 296, 4 297, 3 -0.421 0.202 0.0367 1.436 0.656 0.442 0.974 -0.707 0.534 0.185 0.7321 0.493 0.173 1.4 -0.731 0.527 0.166 0.7811 0.481 0.171 1.35 -1 0.584 0.086 1.065 0.367 0.117 1.15 PRS_PLINK_1e.04 580.3 Nephritis and nephropathy without mention of glomerulonephritis Both 134 5912 11 genitourinary black 5912, 134 1478, 24 1478, 39 1478, 32 1478, 39 0.193 0.0891 0.0301 1.522 1.21 1.02 1.44 0.494 0.254 0.052 1.284 1.64 0.996 2.7 0.306 0.262 0.244 0.6125 1.36 0.812 2.27 0.515 0.254 0.0424 1.372 1.67 1.02 2.75 PRS_PLINK_1e.04 580.31 Nephritis and nephropathy in diseases classified elsewhere Both 49 3330 11 genitourinary black 3330, 49 833, 8 832, 14 832, 11 833, 16 0.242 0.143 0.0899 1.046 1.27 0.963 1.69 0.605 0.406 0.136 0.8663 1.83 0.827 4.05 0.32 0.419 0.445 0.3515 1.38 0.606 3.13 0.768 0.401 0.0553 1.257 2.16 0.983 4.73 PRS_PLINK_1e.04 580.32 Nephritis and nephropathy with pathological lesion Both 89 3365 11 genitourinary black 3365, 89 842, 16 841, 27 841, 21 841, 25 0.154 0.11 0.162 0.7893 1.17 0.94 1.45 0.439 0.307 0.153 0.8163 1.55 0.85 2.83 0.246 0.318 0.44 0.3567 1.28 0.685 2.39 0.39 0.309 0.207 0.685 1.48 0.806 2.71 PRS_PLINK_1e.04 580.4 Renal sclerosis, NOS Both 60 1684 11 genitourinary black 1684, 60 421, 19 421, 16 421, 17 421, 8 -0.162 0.128 0.206 0.6854 0.851 0.662 1.09 -0.194 0.34 0.568 0.2457 0.824 0.423 1.6 -0.156 0.325 0.631 0.1999 0.856 0.453 1.62 -0.848 0.396 0.0323 1.491 0.428 0.197 0.931 PRS_PLINK_1e.04 585 Renal failure Both 1251 18025 11 genitourinary black 18025, 1251 4507, 329 4506, 316 4506, 309 4506, 297 -0.0297 0.0293 0.31 0.5087 0.971 0.917 1.03 -0.0317 0.0817 0.698 0.1559 0.969 0.825 1.14 -0.0687 0.0824 0.405 0.393 0.934 0.794 1.1 -0.106 0.0832 0.204 0.6913 0.9 0.764 1.06 PRS_PLINK_1e.04 585.1 Acute renal failure Both 630 13961 11 genitourinary black 13961, 630 3491, 160 3490, 164 3490, 160 3490, 146 -0.0289 0.0404 0.474 0.3241 0.972 0.898 1.05 0.0364 0.113 0.748 0.1263 1.04 0.831 1.29 0.0115 0.114 0.92 0.03628 1.01 0.809 1.26 -0.0824 0.116 0.478 0.3201 0.921 0.733 1.16 PRS_PLINK_1e.04 585.2 Renal failure NOS Both 73 3753 11 genitourinary black 3753, 73 939, 14 938, 17 938, 25 938, 17 0.104 0.117 0.375 0.4262 1.11 0.882 1.39 0.192 0.341 0.573 0.2416 1.21 0.621 2.36 0.597 0.32 0.0619 1.209 1.82 0.971 3.4 0.2 0.34 0.557 0.2541 1.22 0.627 2.38 PRS_PLINK_1e.04 585.3 Chronic renal failure [CKD] Both 759 15601 11 genitourinary black 15601, 759 3901, 208 3900, 188 3900, 181 3900, 182 -0.0324 0.0372 0.384 0.4158 0.968 0.9 1.04 -0.0901 0.103 0.381 0.4191 0.914 0.747 1.12 -0.149 0.104 0.153 0.8152 0.862 0.703 1.06 -0.135 0.104 0.193 0.7139 0.873 0.712 1.07 PRS_PLINK_1e.04 585.31 Renal dialysis Both 30 3707 11 genitourinary black 3707, 30 927, 11 927, 6 926, 10 927, 3 -0.191 0.164 0.242 0.6158 0.826 0.599 1.14 -0.579 0.45 0.198 0.7031 0.56 0.232 1.35 -0.117 0.4 0.771 0.1131 0.89 0.406 1.95 -1.18 0.549 0.0316 1.501 0.307 0.105 0.901 PRS_PLINK_1e.04 585.32 End stage renal disease Both 45 4852 11 genitourinary black 4852, 45 1213, 17 1213, 11 1213, 8 1213, 9 -0.176 0.138 0.201 0.6972 0.838 0.64 1.1 -0.41 0.36 0.255 0.5941 0.664 0.328 1.34 -0.738 0.394 0.0608 1.216 0.478 0.221 1.03 -0.597 0.38 0.116 0.9345 0.55 0.261 1.16 PRS_PLINK_1e.04 585.33 Chronic Kidney Disease, Stage III Both 255 9646 11 genitourinary black 9646, 255 2412, 69 2411, 59 2411, 60 2412, 67 0.0177 0.0628 0.778 0.1092 1.02 0.9 1.15 -0.174 0.177 0.327 0.4853 0.841 0.594 1.19 -0.151 0.176 0.391 0.4075 0.86 0.609 1.21 -0.0568 0.172 0.741 0.1299 0.945 0.674 1.32 PRS_PLINK_1e.04 585.34 Chronic Kidney Disease, Stage IV Both 33 4030 11 genitourinary black 4030, 33 1008, 10 1007, 5 1007, 8 1008, 10 0.0501 0.161 0.755 0.1219 1.05 0.767 1.44 -0.646 0.47 0.169 0.7723 0.524 0.209 1.32 -0.251 0.42 0.55 0.2593 0.778 0.341 1.77 -0.0194 0.405 0.962 0.0169 0.981 0.443 2.17 PRS_PLINK_1e.04 585.4 Chronic kidney disease, Stage I or II Both 110 4956 11 genitourinary black 4956, 110 1239, 25 1239, 28 1239, 30 1239, 27 0.0473 0.0948 0.617 0.2094 1.05 0.871 1.26 0.104 0.268 0.698 0.156 1.11 0.657 1.87 0.167 0.263 0.525 0.28 1.18 0.706 1.98 0.0747 0.27 0.782 0.107 1.08 0.635 1.83 PRS_PLINK_1e.04 586 Other disorders of the kidney and ureters Both 1987 19738 11 genitourinary black 19738, 1987 4935, 506 4934, 489 4934, 477 4935, 514 -0.00734 0.0236 0.755 0.1218 0.993 0.948 1.04 -0.0279 0.0669 0.677 0.1695 0.973 0.853 1.11 -0.0529 0.0672 0.431 0.3653 0.948 0.831 1.08 0.0203 0.0662 0.759 0.1199 1.02 0.896 1.16 PRS_PLINK_1e.04 586.1 Anatomical abnormatilies of kidney and ureters Both 111 2035 11 genitourinary black 2035, 111 509, 37 509, 20 508, 32 509, 21 -0.237 0.093 0.0108 1.968 0.789 0.657 0.947 -0.627 0.28 0.025 1.603 0.534 0.309 0.924 -0.154 0.244 0.528 0.2776 0.857 0.531 1.38 -0.535 0.274 0.0505 1.297 0.585 0.342 1 PRS_PLINK_1e.04 586.11 Small kidney Both 51 1134 11 genitourinary black 1134, 51 284, 19 283, 10 283, 17 284, 5 -0.272 0.141 0.0541 1.267 0.762 0.577 1 -0.659 0.39 0.0913 1.039 0.517 0.241 1.11 -0.0748 0.33 0.821 0.0858 0.928 0.486 1.77 -1.24 0.464 0.00741 2.13 0.289 0.116 0.717 PRS_PLINK_1e.04 586.12 Vesicoureteral reflux Both 62 895 11 genitourinary black 895, 62 224, 20 224, 12 223, 15 224, 14 -0.24 0.116 0.0389 1.41 0.787 0.627 0.988 -0.464 0.359 0.197 0.7065 0.629 0.311 1.27 -0.233 0.343 0.496 0.3047 0.792 0.404 1.55 -0.295 0.345 0.393 0.406 0.744 0.378 1.46 PRS_PLINK_1e.04 586.2 Cyst of kidney, acquired Both 319 5553 11 genitourinary black 5553, 319 1389, 85 1388, 74 1388, 68 1388, 92 -0.000934 0.0569 0.987 0.00572 0.999 0.894 1.12 -0.12 0.162 0.459 0.3379 0.887 0.646 1.22 -0.198 0.165 0.231 0.6359 0.82 0.593 1.13 0.107 0.154 0.489 0.3105 1.11 0.822 1.5 PRS_PLINK_1e.04 586.3 Vascular disorders of kidney/hypertrophy Both 17 887 11 genitourinary black 887, 17 222, 3 222, 5 221, 2 222, 7 0.31 0.224 0.166 0.7803 1.36 0.879 2.12 0.493 0.599 0.411 0.3862 1.64 0.506 5.3 -0.0182 0.689 0.979 0.009254 0.982 0.254 3.79 0.921 0.591 0.119 0.9255 2.51 0.79 8 PRS_PLINK_1e.04 586.4 Stricture/obstruction of ureter Both 629 8539 11 genitourinary black 8539, 629 2135, 168 2135, 164 2134, 141 2135, 155 -0.0295 0.041 0.472 0.3263 0.971 0.896 1.05 -0.0246 0.113 0.829 0.08167 0.976 0.781 1.22 -0.168 0.118 0.152 0.8174 0.845 0.671 1.06 -0.0775 0.115 0.5 0.301 0.925 0.739 1.16 PRS_PLINK_1e.04 587 Kidney replaced by transpant Both 64 4296 11 genitourinary black 4296, 64 1074, 7 1074, 21 1074, 19 1074, 17 0.0766 0.121 0.527 0.2778 1.08 0.851 1.37 1.01 0.399 0.0112 1.95 2.75 1.26 6 0.889 0.406 0.0286 1.544 2.43 1.1 5.39 0.825 0.406 0.0421 1.375 2.28 1.03 5.05 PRS_PLINK_1e.04 588 Disorders resulting from impaired renal function Both 57 4482 11 genitourinary black 4482, 57 1121, 17 1120, 15 1120, 17 1121, 8 -0.113 0.126 0.37 0.4317 0.893 0.698 1.14 -0.142 0.333 0.67 0.1738 0.868 0.452 1.67 -0.0469 0.325 0.885 0.05302 0.954 0.505 1.8 -0.722 0.39 0.0643 1.192 0.486 0.226 1.04 PRS_PLINK_1e.04 588.1 Renal osteodystrophy Both 2 1520 11 genitourinary black 1520, 2 380, 0 380, 0 380, 1 380, 1 1.07 0.493 0.0303 1.519 2.91 1.11 7.63 0.374 0.936 0.69 0.1613 1.45 0.232 9.09 1.37 1.01 0.174 0.7606 3.94 0.547 28.5 1.09 0.93 0.239 0.6209 2.99 0.483 18.5 PRS_PLINK_1e.04 588.2 Secondary hyperparathyroidism (of renal origin) Both 41 3418 11 genitourinary black 3418, 41 855, 14 854, 9 854, 11 855, 7 -0.0995 0.145 0.494 0.3066 0.905 0.681 1.2 -0.473 0.392 0.228 0.6416 0.623 0.289 1.34 -0.304 0.373 0.415 0.3814 0.738 0.355 1.53 -0.689 0.416 0.0979 1.009 0.502 0.222 1.14 PRS_PLINK_1e.04 589 Abnormal results of function study of kidney Both 166 4611 11 genitourinary black 4611, 166 1153, 44 1153, 38 1152, 40 1153, 44 0.0111 0.0773 0.886 0.05245 1.01 0.869 1.18 -0.18 0.221 0.415 0.3818 0.835 0.541 1.29 -0.0937 0.218 0.667 0.1759 0.911 0.594 1.4 0.00134 0.213 0.995 0.002183 1 0.659 1.52 PRS_PLINK_1e.04 590 Pyelonephritis Both 514 7824 11 genitourinary black 7824, 514 1956, 144 1956, 122 1956, 121 1956, 126 -0.0318 0.0453 0.483 0.3158 0.969 0.886 1.06 -0.177 0.127 0.162 0.7895 0.838 0.654 1.07 -0.163 0.127 0.198 0.7044 0.849 0.663 1.09 -0.137 0.125 0.274 0.562 0.872 0.682 1.11 PRS_PLINK_1e.04 591 Urinary tract infection Both 3887 17023 11 genitourinary black 17023, 3887 4256, 1021 4256, 958 4255, 912 4256, 995 -0.0136 0.0181 0.453 0.3441 0.987 0.952 1.02 -0.075 0.0508 0.14 0.8546 0.928 0.84 1.02 -0.131 0.0514 0.0108 1.966 0.877 0.793 0.97 -0.0374 0.0503 0.457 0.3398 0.963 0.873 1.06 PRS_PLINK_1e.04 592 Cystitis and urethritis Both 1096 12717 11 genitourinary black 12717, 1096 3180, 268 3179, 274 3179, 270 3179, 283 0.0127 0.0316 0.688 0.1624 1.01 0.952 1.08 0.0184 0.0892 0.837 0.07753 1.02 0.855 1.21 0.0025 0.0896 0.978 0.009755 1 0.841 1.2 0.0548 0.0886 0.537 0.2703 1.06 0.888 1.26 PRS_PLINK_1e.04 592.1 Cystitis Both 1022 12179 11 genitourinary black 12179, 1022 3045, 250 3045, 258 3044, 251 3045, 262 0.0114 0.0328 0.727 0.1384 1.01 0.949 1.08 0.0255 0.0921 0.782 0.1066 1.03 0.856 1.23 0.00234 0.0928 0.98 0.008815 1 0.836 1.2 0.047 0.0918 0.609 0.2156 1.05 0.876 1.25 PRS_PLINK_1e.04 592.11 Acute cystitis Both 591 8142 11 genitourinary black 8142, 591 2036, 139 2035, 139 2035, 154 2036, 158 0.0444 0.0428 0.3 0.5231 1.05 0.961 1.14 0.00274 0.123 0.982 0.007772 1 0.788 1.28 0.108 0.121 0.371 0.4308 1.11 0.88 1.41 0.132 0.12 0.27 0.5679 1.14 0.902 1.44 PRS_PLINK_1e.04 592.12 Chronic cystitis Both 82 1099 11 genitourinary black 1099, 82 275, 20 275, 21 274, 16 275, 24 0.0599 0.115 0.604 0.2189 1.06 0.847 1.33 0.03 0.313 0.923 0.0346 1.03 0.558 1.9 -0.235 0.336 0.485 0.3145 0.791 0.409 1.53 0.212 0.305 0.487 0.3123 1.24 0.68 2.25 PRS_PLINK_1e.04 592.13 Chronic interstitial cystitis Both 223 2617 11 genitourinary black 2617, 223 655, 58 654, 50 654, 61 654, 54 0.00687 0.0698 0.922 0.03545 1.01 0.878 1.15 -0.16 0.198 0.419 0.3777 0.852 0.578 1.26 0.0834 0.19 0.66 0.1803 1.09 0.749 1.58 -0.0533 0.194 0.784 0.1058 0.948 0.648 1.39 PRS_PLINK_1e.04 592.2 Urethritis and urethral syndrome Both 89 1219 11 genitourinary black 1219, 89 305, 31 305, 14 304, 19 305, 25 -0.0664 0.108 0.539 0.2682 0.936 0.757 1.16 -0.777 0.323 0.016 1.795 0.46 0.244 0.865 -0.416 0.293 0.156 0.8082 0.66 0.371 1.17 -0.179 0.275 0.515 0.2878 0.836 0.488 1.43 PRS_PLINK_1e.04 593 Hematuria Both 1592 16674 11 genitourinary black 16674, 1592 4169, 421 4168, 385 4168, 387 4169, 398 -0.0201 0.0263 0.443 0.3534 0.98 0.931 1.03 -0.0858 0.074 0.246 0.6092 0.918 0.794 1.06 -0.0832 0.0739 0.26 0.5848 0.92 0.796 1.06 -0.0578 0.0733 0.431 0.3659 0.944 0.818 1.09 PRS_PLINK_1e.04 593.1 Gross hematuria Both 446 6066 11 genitourinary black 6066, 446 1517, 134 1516, 110 1516, 101 1517, 101 -0.104 0.0492 0.0336 1.474 0.901 0.818 0.992 -0.197 0.133 0.138 0.8595 0.821 0.633 1.07 -0.278 0.136 0.0402 1.395 0.757 0.58 0.988 -0.275 0.136 0.0426 1.371 0.759 0.582 0.991 PRS_PLINK_1e.04 593.2 Microscopic hematuria Both 371 4764 11 genitourinary black 4764, 371 1191, 88 1191, 87 1191, 106 1191, 90 0.0188 0.0538 0.727 0.1384 1.02 0.917 1.13 0.0015 0.155 0.992 0.003366 1 0.739 1.36 0.209 0.149 0.161 0.7931 1.23 0.92 1.65 0.0391 0.154 0.8 0.09691 1.04 0.769 1.41 PRS_PLINK_1e.04 594 Urinary calculus Both 2574 19688 11 genitourinary black 19688, 2574 4922, 630 4922, 626 4922, 662 4922, 656 0.0253 0.021 0.229 0.6399 1.03 0.984 1.07 -0.00397 0.06 0.947 0.02352 0.996 0.886 1.12 0.0522 0.0592 0.378 0.4227 1.05 0.938 1.18 0.0403 0.0594 0.497 0.3033 1.04 0.927 1.17 PRS_PLINK_1e.04 594.1 Calculus of kidney Both 2387 19598 11 genitourinary black 19598, 2387 4900, 591 4899, 580 4899, 606 4900, 610 0.0202 0.0217 0.351 0.4552 1.02 0.978 1.06 -0.0149 0.0619 0.81 0.09172 0.985 0.873 1.11 0.0287 0.0613 0.639 0.1944 1.03 0.913 1.16 0.0313 0.0612 0.61 0.2149 1.03 0.915 1.16 PRS_PLINK_1e.04 594.2 Calculus of lower urinary tract Both 132 1405 11 genitourinary black 1405, 132 352, 30 351, 35 351, 32 351, 35 0.0522 0.0927 0.573 0.2415 1.05 0.879 1.26 0.178 0.255 0.486 0.3132 1.19 0.724 1.97 0.0766 0.259 0.767 0.1151 1.08 0.65 1.79 0.124 0.256 0.628 0.2022 1.13 0.686 1.87 PRS_PLINK_1e.04 594.3 Calculus of ureter Both 525 6657 11 genitourinary black 6657, 525 1665, 118 1664, 151 1664, 131 1664, 125 -0.00176 0.0455 0.969 0.01358 0.998 0.913 1.09 0.253 0.127 0.0465 1.333 1.29 1 1.65 0.109 0.131 0.404 0.3933 1.12 0.863 1.44 0.0594 0.132 0.653 0.1854 1.06 0.819 1.37 PRS_PLINK_1e.04 594.8 Renal colic Both 158 2015 11 genitourinary black 2015, 158 504, 36 504, 41 503, 42 504, 39 0.0349 0.0828 0.673 0.172 1.04 0.88 1.22 0.125 0.234 0.593 0.2269 1.13 0.717 1.79 0.185 0.232 0.426 0.3706 1.2 0.764 1.89 0.0666 0.235 0.777 0.1096 1.07 0.674 1.69 PRS_PLINK_1e.04 595 Hydronephrosis Both 589 7917 11 genitourinary black 7917, 589 1980, 144 1979, 158 1979, 129 1979, 157 0.00816 0.0431 0.85 0.07058 1.01 0.926 1.1 0.0972 0.119 0.414 0.3833 1.1 0.873 1.39 -0.102 0.124 0.41 0.3872 0.903 0.707 1.15 0.0897 0.119 0.451 0.3457 1.09 0.866 1.38 PRS_PLINK_1e.04 596 Other disorders of bladder Both 1041 12285 11 genitourinary black 12285, 1041 3072, 264 3071, 251 3071, 253 3071, 272 0.00608 0.0323 0.851 0.07018 1.01 0.944 1.07 -0.0441 0.0915 0.63 0.2009 0.957 0.8 1.14 -0.0412 0.0913 0.652 0.1858 0.96 0.802 1.15 0.0361 0.0898 0.688 0.1627 1.04 0.869 1.24 PRS_PLINK_1e.04 596.1 Bladder neck obstruction Both 114 1288 11 genitourinary black 1288, 114 322, 29 322, 27 322, 24 322, 34 0.0916 0.0942 0.331 0.4806 1.1 0.911 1.32 -0.0554 0.275 0.84 0.07558 0.946 0.552 1.62 -0.197 0.281 0.484 0.3153 0.821 0.473 1.43 0.195 0.261 0.454 0.3429 1.22 0.729 2.03 PRS_PLINK_1e.04 596.5 Functional disorders of bladder Both 597 7477 11 genitourinary black 7477, 597 1870, 152 1869, 138 1869, 149 1869, 157 -0.0182 0.0427 0.671 0.1736 0.982 0.903 1.07 -0.093 0.121 0.444 0.3528 0.911 0.718 1.16 -0.0141 0.119 0.906 0.04294 0.986 0.78 1.25 0.03 0.118 0.799 0.09732 1.03 0.818 1.3 PRS_PLINK_1e.04 597 Other disorders of urethra and urinary tract Both 457 5150 11 genitourinary black 5150, 457 1288, 116 1287, 109 1287, 128 1288, 104 -0.0467 0.0481 0.331 0.4802 0.954 0.869 1.05 -0.0694 0.138 0.615 0.2112 0.933 0.712 1.22 0.0944 0.133 0.478 0.3205 1.1 0.847 1.43 -0.108 0.14 0.439 0.3575 0.898 0.683 1.18 PRS_PLINK_1e.04 597.1 Urethral stricture (not specified as infectious) Both 224 2652 11 genitourinary black 2652, 224 663, 58 663, 54 663, 59 663, 53 -0.021 0.0684 0.759 0.1197 0.979 0.856 1.12 -0.0676 0.194 0.727 0.1383 0.935 0.639 1.37 0.0134 0.19 0.944 0.02517 1.01 0.698 1.47 -0.0716 0.195 0.714 0.1462 0.931 0.635 1.37 PRS_PLINK_1e.04 597.2 Urinary complications NEC Both 341 4435 11 genitourinary black 4435, 341 1109, 89 1109, 97 1108, 85 1109, 70 -0.0755 0.0556 0.175 0.7579 0.927 0.831 1.03 0.0715 0.152 0.639 0.1948 1.07 0.797 1.45 -0.0554 0.157 0.724 0.1402 0.946 0.696 1.29 -0.249 0.164 0.129 0.889 0.78 0.566 1.08 PRS_PLINK_1e.04 597.8 Urethral hypermobility/ISD Both 87 841 11 genitourinary black 841, 87 211, 24 210, 20 210, 19 210, 24 -0.0126 0.109 0.909 0.04161 0.988 0.797 1.22 -0.158 0.311 0.612 0.2133 0.854 0.465 1.57 -0.239 0.315 0.448 0.3491 0.787 0.425 1.46 0.0421 0.301 0.889 0.05111 1.04 0.578 1.88 PRS_PLINK_1e.04 598 Abnormal findings on examination of urine Both 45 545 11 genitourinary black 545, 45 137, 9 136, 14 136, 11 136, 11 0.151 0.156 0.333 0.4781 1.16 0.857 1.58 0.399 0.413 0.334 0.4762 1.49 0.664 3.34 0.0628 0.444 0.888 0.05181 1.06 0.446 2.54 0.297 0.442 0.502 0.2993 1.35 0.566 3.2 PRS_PLINK_1e.04 598.4 Other cells and casts in urine Both 44 465 11 genitourinary black 465, 44 117, 9 116, 13 116, 12 116, 10 0.0864 0.158 0.583 0.2342 1.09 0.801 1.48 0.344 0.427 0.421 0.3761 1.41 0.61 3.26 0.138 0.441 0.755 0.1221 1.15 0.483 2.73 0.0443 0.454 0.922 0.03514 1.05 0.43 2.54 PRS_PLINK_1e.04 599 Other symptoms/disorders or the urinary system Both 5687 17008 11 genitourinary black 17008, 5687 4252, 1428 4252, 1396 4252, 1458 4252, 1404 -0.00818 0.0156 0.6 0.2221 0.992 0.962 1.02 -0.0244 0.0442 0.582 0.2354 0.976 0.895 1.06 0.0146 0.044 0.74 0.1309 1.01 0.931 1.11 -0.0285 0.0441 0.519 0.2849 0.972 0.891 1.06 PRS_PLINK_1e.04 599.1 Urinary obstruction Both 164 2492 11 genitourinary black 2492, 164 623, 46 623, 56 623, 29 623, 33 -0.105 0.0802 0.19 0.7221 0.9 0.769 1.05 0.182 0.205 0.375 0.426 1.2 0.803 1.79 -0.447 0.239 0.0619 1.208 0.639 0.4 1.02 -0.324 0.23 0.16 0.7968 0.723 0.46 1.14 PRS_PLINK_1e.04 599.2 Retention of urine Both 1709 14971 11 genitourinary black 14971, 1709 3743, 416 3743, 433 3742, 431 3743, 429 0.00223 0.0257 0.931 0.03112 1 0.953 1.05 0.0508 0.0729 0.486 0.3134 1.05 0.912 1.21 0.0398 0.0731 0.586 0.232 1.04 0.902 1.2 0.0351 0.0731 0.631 0.2001 1.04 0.898 1.2 PRS_PLINK_1e.04 599.3 Dysuria Both 1861 14838 11 genitourinary black 14838, 1861 3710, 450 3709, 455 3709, 480 3710, 475 0.0234 0.0248 0.345 0.4619 1.02 0.975 1.07 0.00362 0.0706 0.959 0.01811 1 0.874 1.15 0.0618 0.0698 0.376 0.4243 1.06 0.928 1.22 0.0485 0.0699 0.488 0.3116 1.05 0.915 1.2 PRS_PLINK_1e.04 599.4 Urinary incontinence Both 2070 13948 11 genitourinary black 13948, 2070 3487, 500 3487, 516 3487, 546 3487, 507 0.00566 0.0239 0.813 0.09006 1.01 0.96 1.05 0.029 0.068 0.67 0.1742 1.03 0.901 1.18 0.0835 0.0673 0.215 0.6672 1.09 0.953 1.24 0.00884 0.0681 0.897 0.04732 1.01 0.883 1.15 PRS_PLINK_1e.04 599.5 Frequency of urination and polyuria Both 2063 15289 11 genitourinary black 15289, 2063 3823, 528 3822, 482 3822, 527 3822, 526 -0.00733 0.0235 0.755 0.1222 0.993 0.948 1.04 -0.0912 0.0673 0.175 0.7562 0.913 0.8 1.04 0.00247 0.0662 0.97 0.01314 1 0.881 1.14 -0.00806 0.066 0.903 0.04435 0.992 0.872 1.13 PRS_PLINK_1e.04 599.6 Oliguria and anuria Both 110 2479 11 genitourinary black 2479, 110 620, 29 620, 24 619, 30 620, 27 0.0411 0.0961 0.668 0.1749 1.04 0.863 1.26 -0.193 0.272 0.478 0.3204 0.824 0.483 1.41 0.0418 0.26 0.872 0.0593 1.04 0.626 1.74 -0.0354 0.265 0.894 0.04876 0.965 0.574 1.62 PRS_PLINK_1e.04 599.7 Urethral discharge Both 35 461 11 genitourinary black 461, 35 116, 4 115, 10 115, 10 115, 11 0.276 0.174 0.113 0.9456 1.32 0.936 1.85 0.836 0.527 0.113 0.9481 2.31 0.821 6.48 0.775 0.53 0.144 0.8418 2.17 0.768 6.14 0.993 0.531 0.0614 1.212 2.7 0.954 7.65 PRS_PLINK_1e.04 599.8 Other symptoms involving urinary system Both 1999 14643 11 genitourinary black 14643, 1999 3661, 516 3661, 485 3660, 521 3661, 477 -0.0272 0.024 0.256 0.5911 0.973 0.928 1.02 -0.0637 0.0681 0.35 0.4562 0.938 0.821 1.07 0.00561 0.0672 0.934 0.02987 1.01 0.881 1.15 -0.0824 0.0683 0.228 0.6427 0.921 0.806 1.05 PRS_PLINK_1e.04 599.9 Other abnormality of urination Both 1169 12417 11 genitourinary black 12417, 1169 3105, 311 3104, 275 3104, 282 3104, 301 -0.0133 0.0305 0.663 0.1783 0.987 0.93 1.05 -0.117 0.0864 0.175 0.7559 0.889 0.751 1.05 -0.0885 0.0859 0.303 0.5183 0.915 0.773 1.08 -0.024 0.0847 0.777 0.1096 0.976 0.827 1.15 PRS_PLINK_1e.04 600 Hyperplasia of prostate Male 1009 4454 11 genitourinary black 4454, 1009 1114, 269 1113, 280 1113, 232 1114, 228 -0.0653 0.0361 0.0706 1.151 0.937 0.873 1.01 0.0438 0.103 0.671 0.1735 1.04 0.854 1.28 -0.17 0.105 0.106 0.9737 0.843 0.686 1.04 -0.182 0.106 0.0856 1.068 0.834 0.678 1.03 PRS_PLINK_1e.04 601 Inflammatory diseases of prostate Male 332 3978 11 genitourinary black 3978, 332 995, 59 994, 92 994, 83 995, 98 0.174 0.0576 0.0025 2.602 1.19 1.06 1.33 0.447 0.171 0.00907 2.043 1.56 1.12 2.19 0.331 0.174 0.0579 1.237 1.39 0.989 1.96 0.506 0.169 0.00279 2.554 1.66 1.19 2.31 PRS_PLINK_1e.04 601.1 Prostatitis Male 142 1583 11 genitourinary black 1583, 142 396, 36 396, 35 395, 33 396, 38 0.0557 0.0859 0.517 0.2868 1.06 0.893 1.25 -0.00772 0.245 0.975 0.01105 0.992 0.614 1.6 -0.0835 0.248 0.737 0.1327 0.92 0.565 1.5 0.0389 0.239 0.871 0.06022 1.04 0.651 1.66 PRS_PLINK_1e.04 601.11 Acute prostatitis Male 48 419 11 genitourinary black 419, 48 105, 15 105, 12 104, 7 105, 14 -0.117 0.143 0.413 0.3842 0.889 0.672 1.18 -0.174 0.406 0.668 0.175 0.84 0.38 1.86 -0.705 0.456 0.123 0.9115 0.494 0.202 1.21 -0.137 0.396 0.73 0.1369 0.872 0.401 1.9 PRS_PLINK_1e.04 601.12 Chronic prostatitis Male 29 321 11 genitourinary black 321, 29 81, 4 80, 8 80, 6 80, 11 0.346 0.199 0.0813 1.09 1.41 0.958 2.09 0.839 0.592 0.156 0.8058 2.31 0.725 7.38 0.329 0.629 0.601 0.2209 1.39 0.405 4.77 0.883 0.56 0.115 0.9395 2.42 0.807 7.25 PRS_PLINK_1e.04 601.3 Orchitis and epididymitis Male 144 1709 11 genitourinary black 1709, 144 428, 21 427, 41 427, 40 427, 42 0.231 0.0894 0.00963 2.016 1.26 1.06 1.5 0.663 0.27 0.0142 1.846 1.94 1.14 3.29 0.601 0.271 0.0266 1.575 1.82 1.07 3.1 0.689 0.268 0.0101 1.996 1.99 1.18 3.37 PRS_PLINK_1e.04 601.4 Balanoposthitis Male 41 482 11 genitourinary black 482, 41 121, 8 120, 6 120, 12 121, 15 0.316 0.156 0.0428 1.369 1.37 1.01 1.86 -0.148 0.51 0.771 0.1127 0.862 0.317 2.34 0.377 0.451 0.403 0.395 1.46 0.603 3.53 0.723 0.439 0.0993 1.003 2.06 0.872 4.87 PRS_PLINK_1e.04 601.8 Other inflammatory disorders of male genital organs Male 40 629 11 genitourinary black 629, 40 158, 1 157, 22 157, 8 157, 9 0.231 0.158 0.144 0.8408 1.26 0.924 1.72 2.81 0.791 0.000383 3.417 16.6 3.52 78.2 2.01 0.853 0.0185 1.734 7.46 1.4 39.7 1.79 0.784 0.0224 1.651 5.99 1.29 27.8 PRS_PLINK_1e.04 602 Other disorders of prostate Male 110 996 11 genitourinary black 996, 110 249, 28 249, 33 249, 21 249, 28 -0.0597 0.0959 0.533 0.2729 0.942 0.781 1.14 0.169 0.271 0.532 0.2738 1.18 0.697 2.01 -0.262 0.297 0.378 0.423 0.77 0.43 1.38 0.00473 0.279 0.986 0.005909 1 0.581 1.74 PRS_PLINK_1e.04 602.3 Dysplasia of prostate Male 30 197 11 genitourinary black 197, 30 50, 11 49, 9 49, 5 49, 5 -0.314 0.188 0.0955 1.02 0.731 0.505 1.06 -0.0506 0.494 0.918 0.03695 0.951 0.361 2.5 -0.608 0.596 0.308 0.512 0.545 0.169 1.75 -0.63 0.559 0.26 0.5845 0.533 0.178 1.59 PRS_PLINK_1e.04 603 Other disorders of testis Male 175 2023 11 genitourinary black 2023, 175 506, 40 506, 46 505, 44 506, 45 0.0136 0.0752 0.857 0.06709 1.01 0.875 1.17 0.125 0.221 0.572 0.2423 1.13 0.734 1.75 0.101 0.224 0.654 0.1845 1.11 0.712 1.72 0.121 0.223 0.588 0.2306 1.13 0.728 1.75 PRS_PLINK_1e.04 603.1 Hydrocele Male 101 1219 11 genitourinary black 1219, 101 305, 21 305, 29 304, 24 305, 27 0.0726 0.0986 0.461 0.3359 1.08 0.886 1.3 0.293 0.291 0.313 0.5044 1.34 0.758 2.37 0.18 0.304 0.553 0.2574 1.2 0.66 2.17 0.292 0.299 0.329 0.4827 1.34 0.745 2.4 PRS_PLINK_1e.04 603.2 Spermatocele Male 71 730 11 genitourinary black 730, 71 183, 18 182, 17 182, 23 183, 13 -0.061 0.122 0.618 0.2091 0.941 0.74 1.2 -0.094 0.341 0.783 0.1065 0.91 0.467 1.77 0.239 0.325 0.462 0.3352 1.27 0.671 2.4 -0.365 0.367 0.32 0.4946 0.694 0.338 1.43 PRS_PLINK_1e.04 604 Disorders of penis Male 241 2893 11 genitourinary black 2893, 241 724, 53 723, 59 723, 68 723, 61 0.0677 0.0656 0.302 0.5199 1.07 0.941 1.22 0.123 0.194 0.526 0.2793 1.13 0.774 1.65 0.225 0.189 0.233 0.6318 1.25 0.865 1.81 0.169 0.193 0.382 0.4182 1.18 0.811 1.73 PRS_PLINK_1e.04 604.1 Redundant prepuce and phimosis/BXO Male 35 569 11 genitourinary black 569, 35 143, 9 142, 11 142, 5 142, 10 -0.0356 0.163 0.827 0.08255 0.965 0.701 1.33 0.213 0.443 0.631 0.2002 1.24 0.519 2.95 -0.544 0.527 0.302 0.5196 0.581 0.207 1.63 0.239 0.461 0.605 0.2185 1.27 0.514 3.13 PRS_PLINK_1e.04 604.3 Peyronie's disease Male 89 884 11 genitourinary black 884, 89 221, 24 221, 24 221, 20 221, 21 0.00901 0.109 0.934 0.02968 1.01 0.816 1.25 -0.0319 0.297 0.915 0.03874 0.969 0.541 1.74 -0.272 0.311 0.383 0.4169 0.762 0.414 1.4 -0.138 0.307 0.654 0.1847 0.871 0.478 1.59 PRS_PLINK_1e.04 605 Erectile dysfunction [ED] Male 1136 5693 11 genitourinary black 5693, 1136 1424, 256 1423, 291 1423, 313 1423, 276 0.0331 0.0329 0.314 0.5026 1.03 0.969 1.1 0.154 0.0956 0.107 0.9701 1.17 0.967 1.41 0.198 0.0943 0.036 1.443 1.22 1.01 1.47 0.0706 0.0961 0.463 0.3347 1.07 0.889 1.3 PRS_PLINK_1e.04 608 Other disorders of male genital organs Male 635 6701 11 genitourinary black 6701, 635 1676, 142 1675, 166 1675, 151 1675, 176 0.0645 0.0412 0.117 0.9307 1.07 0.984 1.16 0.164 0.119 0.167 0.7761 1.18 0.933 1.49 0.0579 0.122 0.634 0.1981 1.06 0.835 1.34 0.218 0.118 0.0635 1.197 1.24 0.988 1.57 PRS_PLINK_1e.04 609 Male infertility and abnormal spermatozoa Male 241 2456 11 genitourinary black 2456, 241 614, 59 614, 67 614, 59 614, 56 -0.0324 0.068 0.634 0.198 0.968 0.847 1.11 0.111 0.185 0.548 0.2609 1.12 0.777 1.61 -0.00485 0.191 0.98 0.00891 0.995 0.685 1.45 -0.0478 0.193 0.804 0.0947 0.953 0.653 1.39 PRS_PLINK_1e.04 609.1 Infertility, male Male 197 1934 11 genitourinary black 1934, 197 484, 50 483, 53 483, 48 484, 46 -0.0374 0.0756 0.621 0.207 0.963 0.831 1.12 0.0432 0.205 0.833 0.07925 1.04 0.699 1.56 -0.0367 0.209 0.861 0.06523 0.964 0.64 1.45 -0.08 0.211 0.704 0.1522 0.923 0.611 1.4 PRS_PLINK_1e.04 609.11 Azoospermia and oligospermia Male 74 689 11 genitourinary black 689, 74 173, 18 172, 22 172, 17 172, 17 -0.042 0.128 0.742 0.1297 0.959 0.747 1.23 0.212 0.327 0.516 0.2877 1.24 0.652 2.35 -0.0736 0.342 0.83 0.08098 0.929 0.475 1.82 -0.0812 0.344 0.814 0.08961 0.922 0.47 1.81 PRS_PLINK_1e.04 609.2 Abnormal spermatozoa Male 70 769 11 genitourinary black 769, 70 193, 17 192, 24 192, 12 192, 17 0.017 0.123 0.89 0.05037 1.02 0.799 1.3 0.316 0.325 0.33 0.481 1.37 0.726 2.6 -0.356 0.373 0.341 0.4678 0.701 0.337 1.46 0.0568 0.345 0.869 0.06084 1.06 0.538 2.08 PRS_PLINK_1e.04 610 Benign mammary dysplasias Female 1958 9460 11 genitourinary black 9460, 1958 2365, 451 2365, 474 2365, 528 2365, 505 0.0391 0.0255 0.125 0.9047 1.04 0.989 1.09 0.0356 0.0728 0.625 0.2043 1.04 0.898 1.2 0.153 0.0711 0.0311 1.507 1.17 1.01 1.34 0.103 0.0717 0.151 0.8201 1.11 0.963 1.28 PRS_PLINK_1e.04 610.1 Cystic mastopathy Female 850 7436 11 genitourinary black 7436, 850 1859, 206 1859, 206 1859, 232 1859, 206 -0.000617 0.0367 0.987 0.005869 0.999 0.93 1.07 -0.00228 0.104 0.983 0.007658 0.998 0.814 1.22 0.118 0.101 0.245 0.6116 1.12 0.923 1.37 -0.00426 0.104 0.967 0.01441 0.996 0.812 1.22 PRS_PLINK_1e.04 610.2 Fibroadenosis of breast Female 35 350 11 genitourinary black 350, 35 88, 13 87, 7 87, 7 88, 8 -0.144 0.188 0.445 0.3518 0.866 0.599 1.25 -0.561 0.476 0.238 0.6228 0.571 0.224 1.45 -0.442 0.484 0.362 0.4419 0.643 0.249 1.66 -0.464 0.463 0.316 0.5 0.629 0.254 1.56 PRS_PLINK_1e.04 610.4 Benign neoplasm of breast Female 1546 9369 11 genitourinary black 9369, 1546 2343, 348 2342, 377 2342, 414 2342, 407 0.049 0.028 0.0804 1.095 1.05 0.994 1.11 0.0707 0.0806 0.38 0.4197 1.07 0.916 1.26 0.175 0.0789 0.0267 1.574 1.19 1.02 1.39 0.154 0.0791 0.0515 1.289 1.17 0.999 1.36 PRS_PLINK_1e.04 610.8 Other specified benign mammary dysplasias Female 668 6329 11 genitourinary black 6329, 668 1583, 152 1582, 167 1582, 183 1582, 166 0.0199 0.0413 0.63 0.2008 1.02 0.941 1.11 0.1 0.117 0.393 0.4057 1.11 0.878 1.39 0.188 0.115 0.103 0.9864 1.21 0.963 1.51 0.089 0.118 0.449 0.3481 1.09 0.868 1.38 PRS_PLINK_1e.04 611 Abnormal findings on mammogram or breast exam Both 3040 10282 11 genitourinary black 10282, 3040 2571, 730 2570, 724 2570, 795 2571, 791 0.0364 0.0214 0.0884 1.054 1.04 0.995 1.08 -0.0202 0.0609 0.74 0.1306 0.98 0.87 1.1 0.0833 0.0598 0.164 0.7854 1.09 0.967 1.22 0.0744 0.0599 0.214 0.6703 1.08 0.958 1.21 PRS_PLINK_1e.04 611.1 Abnormal mammogram Both 2462 8836 11 genitourinary black 8836, 2462 2209, 606 2209, 571 2209, 640 2209, 645 0.0376 0.0235 0.11 0.9598 1.04 0.992 1.09 -0.0723 0.067 0.281 0.552 0.93 0.816 1.06 0.0571 0.0656 0.384 0.4156 1.06 0.931 1.2 0.0598 0.0654 0.36 0.4435 1.06 0.934 1.21 PRS_PLINK_1e.04 611.11 Mammographic microcalcification Both 481 4695 11 genitourinary black 4695, 481 1174, 101 1174, 119 1173, 133 1174, 128 0.0791 0.0489 0.106 0.9754 1.08 0.983 1.19 0.165 0.141 0.242 0.6164 1.18 0.895 1.56 0.278 0.138 0.0433 1.363 1.32 1.01 1.73 0.224 0.139 0.106 0.975 1.25 0.953 1.64 PRS_PLINK_1e.04 611.3 Lump or mass in breast Both 1813 10278 11 genitourinary black 10278, 1813 2570, 429 2569, 437 2569, 494 2570, 453 0.0276 0.0261 0.29 0.5382 1.03 0.977 1.08 0.00622 0.0743 0.933 0.03 1.01 0.87 1.16 0.14 0.0723 0.0524 1.281 1.15 0.999 1.33 0.0538 0.0736 0.464 0.333 1.06 0.914 1.22 PRS_PLINK_1e.04 612 Breast conditions, congenital or relating to hormones Both 598 6140 11 genitourinary black 6140, 598 1535, 129 1535, 155 1535, 165 1535, 149 0.028 0.0437 0.521 0.2832 1.03 0.944 1.12 0.185 0.124 0.137 0.8639 1.2 0.943 1.53 0.25 0.122 0.0407 1.39 1.28 1.01 1.63 0.144 0.125 0.25 0.6012 1.15 0.904 1.48 PRS_PLINK_1e.04 612.1 Galactorrhea Both 84 977 11 genitourinary black 977, 84 245, 22 244, 17 244, 24 244, 21 -0.0256 0.114 0.823 0.08476 0.975 0.78 1.22 -0.206 0.33 0.533 0.2734 0.814 0.426 1.56 0.092 0.302 0.761 0.1186 1.1 0.606 1.98 -0.0476 0.313 0.879 0.05607 0.953 0.517 1.76 PRS_PLINK_1e.04 612.2 Hypertrophy of breast (Gynecomastia) Both 425 4502 11 genitourinary black 4502, 425 1126, 91 1125, 124 1125, 105 1126, 105 0.0141 0.052 0.787 0.1042 1.01 0.916 1.12 0.313 0.143 0.0289 1.539 1.37 1.03 1.81 0.141 0.148 0.34 0.4685 1.15 0.862 1.54 0.147 0.148 0.321 0.4934 1.16 0.866 1.55 PRS_PLINK_1e.04 612.3 Congenital anomalies of breast Both 56 528 11 genitourinary black 528, 56 132, 8 132, 15 132, 20 132, 13 0.0747 0.132 0.573 0.2422 1.08 0.831 1.4 0.682 0.439 0.12 0.9212 1.98 0.837 4.68 0.84 0.413 0.0418 1.379 2.32 1.03 5.2 0.47 0.441 0.287 0.5424 1.6 0.674 3.8 PRS_PLINK_1e.04 613 Other nonmalignant breast conditions Both 2043 12145 11 genitourinary black 12145, 2043 3037, 473 3036, 488 3036, 557 3036, 524 0.0406 0.0243 0.0951 1.022 1.04 0.993 1.09 0.0311 0.0699 0.657 0.1825 1.03 0.899 1.18 0.161 0.0679 0.0178 1.75 1.17 1.03 1.34 0.101 0.0688 0.14 0.8531 1.11 0.967 1.27 PRS_PLINK_1e.04 613.1 Inflammatory disease of breast Both 337 3325 11 genitourinary black 3325, 337 832, 70 831, 82 831, 86 831, 99 0.127 0.0592 0.0315 1.501 1.14 1.01 1.28 0.175 0.169 0.301 0.5219 1.19 0.856 1.66 0.211 0.168 0.207 0.6833 1.24 0.889 1.72 0.339 0.163 0.0367 1.435 1.4 1.02 1.93 PRS_PLINK_1e.04 613.5 Mastodynia Both 882 8715 11 genitourinary black 8715, 882 2179, 215 2179, 210 2178, 244 2179, 212 -0.00559 0.0358 0.876 0.05749 0.994 0.927 1.07 -0.0119 0.102 0.907 0.04255 0.988 0.81 1.21 0.123 0.0981 0.211 0.6766 1.13 0.933 1.37 -0.00457 0.101 0.964 0.01591 0.995 0.816 1.21 PRS_PLINK_1e.04 613.7 Other signs and symptoms in breast Both 460 4794 11 genitourinary black 4794, 460 1199, 109 1198, 114 1198, 126 1199, 111 0.00665 0.0489 0.892 0.04968 1.01 0.915 1.11 0.0527 0.14 0.706 0.151 1.05 0.801 1.39 0.138 0.136 0.312 0.5052 1.15 0.878 1.5 0.00583 0.14 0.967 0.01466 1.01 0.764 1.32 PRS_PLINK_1e.04 613.8 Other specified disorders of breast Both 503 5074 11 genitourinary black 5074, 503 1269, 106 1268, 114 1268, 148 1269, 135 0.0995 0.0477 0.0369 1.433 1.1 1.01 1.21 0.0673 0.14 0.631 0.2 1.07 0.813 1.41 0.325 0.132 0.014 1.853 1.38 1.07 1.79 0.233 0.135 0.0843 1.074 1.26 0.969 1.64 PRS_PLINK_1e.04 613.9 Breast disorder NOS Both 712 6871 11 genitourinary black 6871, 712 1718, 166 1718, 166 1717, 198 1718, 182 0.0538 0.04 0.178 0.7497 1.06 0.976 1.14 0.00329 0.115 0.977 0.01006 1 0.801 1.26 0.181 0.11 0.101 0.9946 1.2 0.965 1.49 0.0911 0.112 0.417 0.3795 1.1 0.879 1.37 PRS_PLINK_1e.04 614 Inflammatory diseases of female pelvic organs Female 2108 10987 11 genitourinary black 10987, 2108 2747, 526 2747, 518 2746, 509 2747, 554 0.0288 0.0242 0.233 0.6323 1.03 0.982 1.08 -0.0199 0.0678 0.769 0.114 0.98 0.858 1.12 -0.0344 0.068 0.613 0.2122 0.966 0.846 1.1 0.0614 0.067 0.36 0.444 1.06 0.932 1.21 PRS_PLINK_1e.04 614.1 Pelvic peritoneal adhesions, female (postoperative) (postinfection) Female 186 1982 11 genitourinary black 1982, 186 496, 50 495, 40 495, 50 496, 46 -0.00254 0.0772 0.974 0.01153 0.997 0.857 1.16 -0.216 0.218 0.323 0.4912 0.806 0.525 1.24 0.00506 0.208 0.981 0.008531 1.01 0.669 1.51 -0.0907 0.211 0.667 0.1761 0.913 0.604 1.38 PRS_PLINK_1e.04 614.3 Pelvic inflammatory disease (PID) Female 264 3003 11 genitourinary black 3003, 264 751, 80 751, 59 750, 63 751, 61 -0.0812 0.0629 0.197 0.7064 0.922 0.815 1.04 -0.292 0.177 0.0989 1.005 0.746 0.527 1.06 -0.231 0.174 0.185 0.7338 0.794 0.564 1.12 -0.248 0.176 0.16 0.7972 0.781 0.553 1.1 PRS_PLINK_1e.04 614.31 Acute inflammatory pelvic disease Female 59 651 11 genitourinary black 651, 59 163, 19 163, 14 162, 13 163, 13 -0.124 0.129 0.338 0.471 0.883 0.685 1.14 -0.222 0.36 0.538 0.2692 0.801 0.395 1.62 -0.312 0.361 0.387 0.4118 0.732 0.36 1.49 -0.331 0.366 0.366 0.4363 0.718 0.35 1.47 PRS_PLINK_1e.04 614.32 Chronic inflammatory pelvic disease Female 98 1083 11 genitourinary black 1083, 98 271, 30 271, 25 270, 23 271, 20 -0.216 0.105 0.0395 1.403 0.805 0.656 0.99 -0.267 0.283 0.345 0.4618 0.766 0.44 1.33 -0.241 0.285 0.399 0.3993 0.786 0.449 1.37 -0.471 0.301 0.118 0.9298 0.625 0.346 1.13 PRS_PLINK_1e.04 614.33 Pelvic inflammatory disease, NOS Female 134 1562 11 genitourinary black 1562, 134 391, 44 390, 20 390, 33 391, 36 0.00244 0.0876 0.978 0.009773 1 0.844 1.19 -0.725 0.272 0.00765 2.116 0.484 0.284 0.825 -0.28 0.236 0.236 0.627 0.756 0.476 1.2 -0.177 0.233 0.447 0.35 0.838 0.53 1.32 PRS_PLINK_1e.04 614.4 Inflammatory diseases of uterus, except cervix Female 115 1162 11 genitourinary black 1162, 115 291, 25 290, 31 290, 33 291, 26 -0.00186 0.0966 0.985 0.006734 0.998 0.826 1.21 0.229 0.277 0.409 0.3881 1.26 0.73 2.16 0.275 0.272 0.313 0.5049 1.32 0.772 2.24 0.128 0.288 0.658 0.1816 1.14 0.646 2 PRS_PLINK_1e.04 614.5 Inflammatory disease of cervix, vagina, and vulva Female 1821 10967 11 genitourinary black 10967, 1821 2742, 443 2742, 456 2741, 438 2742, 483 0.0402 0.0257 0.119 0.9258 1.04 0.99 1.09 0.0252 0.0723 0.728 0.138 1.03 0.89 1.18 -0.0108 0.0729 0.882 0.0545 0.989 0.858 1.14 0.0993 0.0716 0.165 0.7818 1.1 0.96 1.27 PRS_PLINK_1e.04 614.51 Cervicitis and endocervicitis Female 158 1785 11 genitourinary black 1785, 158 447, 46 446, 44 446, 32 446, 35 -0.161 0.0804 0.0452 1.345 0.851 0.727 0.997 -0.0271 0.218 0.901 0.04527 0.973 0.635 1.49 -0.341 0.235 0.148 0.8311 0.711 0.449 1.13 -0.274 0.23 0.233 0.6319 0.761 0.485 1.19 PRS_PLINK_1e.04 614.52 Vaginitis and vulvovaginitis Female 1563 10781 11 genitourinary black 10781, 1563 2696, 378 2695, 392 2695, 377 2695, 415 0.0472 0.0276 0.0866 1.063 1.05 0.993 1.11 0.0299 0.0773 0.699 0.1553 1.03 0.885 1.2 -0.00786 0.0779 0.92 0.03638 0.992 0.852 1.16 0.104 0.0765 0.172 0.7633 1.11 0.955 1.29 PRS_PLINK_1e.04 614.53 Cyst or abscess of Bartholin's gland Female 85 806 11 genitourinary black 806, 85 202, 18 201, 23 201, 22 202, 22 0.0626 0.115 0.587 0.2314 1.06 0.849 1.33 0.249 0.322 0.439 0.3573 1.28 0.682 2.41 0.17 0.325 0.601 0.221 1.19 0.627 2.24 0.188 0.323 0.56 0.2515 1.21 0.641 2.27 PRS_PLINK_1e.04 614.54 Abscess or ulceration of vulva Female 112 1354 11 genitourinary black 1354, 112 339, 32 338, 25 338, 23 339, 32 0.048 0.0995 0.63 0.2009 1.05 0.863 1.28 -0.215 0.272 0.43 0.3668 0.806 0.473 1.38 -0.346 0.276 0.21 0.6775 0.708 0.412 1.22 0.0173 0.258 0.946 0.02391 1.02 0.614 1.69 PRS_PLINK_1e.04 615 Endometriosis Female 894 8823 11 genitourinary black 8823, 894 2206, 220 2206, 216 2205, 224 2206, 234 0.0277 0.0354 0.434 0.3627 1.03 0.959 1.1 -0.0163 0.1 0.871 0.05982 0.984 0.808 1.2 0.0244 0.0994 0.806 0.09349 1.02 0.843 1.25 0.058 0.0984 0.556 0.2553 1.06 0.874 1.29 PRS_PLINK_1e.04 618 Genital prolapse Female 989 9039 11 genitourinary black 9039, 989 2260, 252 2260, 236 2259, 238 2260, 263 0.0165 0.034 0.627 0.203 1.02 0.951 1.09 -0.0692 0.0952 0.468 0.3302 0.933 0.774 1.12 -0.0612 0.0951 0.52 0.2837 0.941 0.781 1.13 0.0331 0.0931 0.722 0.1412 1.03 0.861 1.24 PRS_PLINK_1e.04 618.1 Prolapse of vaginal walls Female 664 6089 11 genitourinary black 6089, 664 1523, 164 1522, 155 1522, 165 1522, 180 0.014 0.0415 0.736 0.1332 1.01 0.935 1.1 -0.0623 0.117 0.595 0.2253 0.94 0.747 1.18 0.00571 0.116 0.961 0.01742 1.01 0.802 1.26 0.0885 0.114 0.436 0.3602 1.09 0.874 1.37 PRS_PLINK_1e.04 618.2 Uterine/Uterovaginal prolapse Female 259 2338 11 genitourinary black 2338, 259 585, 67 584, 53 584, 74 585, 65 0.027 0.0656 0.681 0.1666 1.03 0.903 1.17 -0.229 0.191 0.23 0.6387 0.795 0.547 1.16 0.0944 0.178 0.595 0.2256 1.1 0.776 1.56 -0.0261 0.182 0.886 0.05263 0.974 0.682 1.39 PRS_PLINK_1e.04 618.5 Prolapse of vaginal vault after hysterectomy Female 149 1206 11 genitourinary black 1206, 149 302, 34 301, 33 301, 38 302, 44 0.143 0.0883 0.106 0.974 1.15 0.97 1.37 -0.0127 0.255 0.96 0.01754 0.987 0.599 1.63 0.0838 0.248 0.736 0.1334 1.09 0.669 1.77 0.271 0.24 0.259 0.5871 1.31 0.819 2.1 PRS_PLINK_1e.04 618.6 Vaginal enterocele, congenital or acquired Female 177 2045 11 genitourinary black 2045, 177 512, 43 511, 52 511, 39 511, 43 0.0251 0.0792 0.751 0.1242 1.03 0.878 1.2 0.195 0.213 0.36 0.4435 1.22 0.8 1.84 -0.0898 0.227 0.692 0.1599 0.914 0.586 1.43 0.00639 0.221 0.977 0.01012 1.01 0.652 1.55 PRS_PLINK_1e.04 619 Noninflammatory female genital disorders Female 3303 10374 11 genitourinary black 10374, 3303 2593, 846 2593, 820 2593, 808 2594, 829 0.0145 0.0203 0.474 0.3242 1.01 0.975 1.06 -0.0377 0.0566 0.506 0.2958 0.963 0.862 1.08 -0.0463 0.0567 0.414 0.3825 0.955 0.854 1.07 -0.0128 0.0565 0.821 0.08589 0.987 0.884 1.1 PRS_PLINK_1e.04 619.1 Noninflammatory disorders of ovary, fallopian tube, and broad ligament Female 743 7643 11 genitourinary black 7643, 743 1910, 183 1911, 182 1910, 183 1911, 195 0.0343 0.0388 0.377 0.4241 1.03 0.959 1.12 -0.0103 0.109 0.925 0.03381 0.99 0.799 1.23 -0.00558 0.109 0.959 0.01806 0.994 0.803 1.23 0.055 0.108 0.61 0.2147 1.06 0.855 1.31 PRS_PLINK_1e.04 619.2 Disorders of uterus, NEC Female 320 3485 11 genitourinary black 3485, 320 872, 83 871, 66 871, 86 871, 85 0.0502 0.0584 0.39 0.4087 1.05 0.938 1.18 -0.225 0.17 0.186 0.7307 0.798 0.572 1.11 0.0317 0.16 0.843 0.07416 1.03 0.754 1.41 0.037 0.16 0.818 0.08733 1.04 0.758 1.42 PRS_PLINK_1e.04 619.3 Noninflammatory disorders of cervix Female 283 2995 11 genitourinary black 2995, 283 749, 75 749, 66 748, 59 749, 83 0.0182 0.061 0.765 0.1161 1.02 0.904 1.15 -0.129 0.175 0.461 0.3368 0.879 0.624 1.24 -0.234 0.18 0.193 0.7146 0.791 0.556 1.13 0.123 0.167 0.46 0.3377 1.13 0.816 1.57 PRS_PLINK_1e.04 619.4 Noninflammatory disorders of vagina Female 1482 10295 11 genitourinary black 10295, 1482 2573, 398 2574, 363 2573, 378 2574, 343 -0.0133 0.0282 0.638 0.1953 0.987 0.934 1.04 -0.0955 0.078 0.221 0.6554 0.909 0.78 1.06 -0.0553 0.0774 0.475 0.323 0.946 0.813 1.1 -0.137 0.0793 0.0847 1.072 0.872 0.747 1.02 PRS_PLINK_1e.04 619.5 Noninflammatory disorders of vulva and perineum Female 597 6506 11 genitourinary black 6506, 597 1626, 161 1626, 153 1626, 142 1627, 141 -0.0233 0.0428 0.586 0.2322 0.977 0.898 1.06 -0.0549 0.118 0.642 0.1926 0.947 0.751 1.19 -0.131 0.12 0.275 0.5604 0.877 0.693 1.11 -0.13 0.12 0.28 0.5522 0.878 0.694 1.11 PRS_PLINK_1e.04 620 Dysplasia of female genital organs Female 232 2318 11 genitourinary black 2318, 232 580, 62 579, 57 579, 54 580, 58 -0.0135 0.0701 0.847 0.07206 0.987 0.86 1.13 -0.0569 0.191 0.766 0.1158 0.945 0.65 1.37 -0.116 0.193 0.548 0.2613 0.89 0.609 1.3 -0.0675 0.19 0.723 0.141 0.935 0.644 1.36 PRS_PLINK_1e.04 620.1 Dysplasia of cervix Female 127 1207 11 genitourinary black 1207, 127 302, 30 302, 31 301, 30 302, 35 0.0028 0.0932 0.976 0.01055 1 0.835 1.2 0.103 0.266 0.698 0.1562 1.11 0.659 1.87 0.0768 0.269 0.775 0.1107 1.08 0.638 1.83 0.179 0.261 0.494 0.3061 1.2 0.717 1.99 PRS_PLINK_1e.04 621 Endometrial hyperplasia Female 172 2399 11 genitourinary black 2399, 172 600, 45 600, 49 599, 45 600, 33 -0.0881 0.0794 0.268 0.5725 0.916 0.784 1.07 0.0991 0.212 0.64 0.1938 1.1 0.729 1.67 0.00244 0.216 0.991 0.003935 1 0.657 1.53 -0.308 0.233 0.185 0.7318 0.735 0.466 1.16 PRS_PLINK_1e.04 622 Polyp of female genital organs Female 718 7661 11 genitourinary black 7661, 718 1916, 171 1915, 199 1915, 174 1915, 174 0.0137 0.0394 0.728 0.138 1.01 0.938 1.1 0.159 0.109 0.144 0.8403 1.17 0.947 1.45 0.0228 0.112 0.839 0.07608 1.02 0.821 1.27 0.0235 0.112 0.834 0.07864 1.02 0.822 1.28 PRS_PLINK_1e.04 622.1 Polyp of corpus uteri Female 545 6105 11 genitourinary black 6105, 545 1527, 137 1526, 138 1526, 133 1526, 137 0.012 0.045 0.789 0.1028 1.01 0.927 1.11 0.0141 0.126 0.911 0.04071 1.01 0.792 1.3 -0.0263 0.127 0.836 0.07793 0.974 0.76 1.25 0.00282 0.126 0.982 0.007827 1 0.784 1.28 PRS_PLINK_1e.04 622.2 Mucous polyp of cervix Female 228 2324 11 genitourinary black 2324, 228 581, 50 581, 62 581, 54 581, 62 0.0901 0.0714 0.207 0.6832 1.09 0.951 1.26 0.221 0.197 0.261 0.5826 1.25 0.848 1.84 0.0932 0.202 0.645 0.1908 1.1 0.739 1.63 0.245 0.198 0.217 0.6643 1.28 0.866 1.88 PRS_PLINK_1e.04 623 Hypertrophy of female genital organs Female 420 4565 11 genitourinary black 4565, 420 1142, 116 1141, 106 1141, 97 1141, 101 -0.04 0.0509 0.432 0.3645 0.961 0.869 1.06 -0.0924 0.14 0.51 0.2928 0.912 0.693 1.2 -0.17 0.143 0.233 0.633 0.843 0.637 1.12 -0.138 0.142 0.331 0.4796 0.871 0.66 1.15 PRS_PLINK_1e.04 624 Symptoms involving female genital tract Female 845 7757 11 genitourinary black 7757, 845 1940, 225 1939, 201 1939, 219 1939, 199 -0.0188 0.0368 0.61 0.2146 0.981 0.913 1.05 -0.124 0.102 0.226 0.6456 0.884 0.723 1.08 -0.033 0.1 0.742 0.1298 0.968 0.795 1.18 -0.12 0.102 0.241 0.6171 0.887 0.726 1.08 PRS_PLINK_1e.04 624.1 Dystrophy of female genital tract Female 84 956 11 genitourinary black 956, 84 239, 16 239, 19 239, 25 239, 24 0.159 0.115 0.165 0.7819 1.17 0.936 1.47 0.216 0.342 0.529 0.2767 1.24 0.634 2.43 0.466 0.325 0.152 0.8184 1.59 0.842 3.01 0.377 0.324 0.245 0.6116 1.46 0.772 2.75 PRS_PLINK_1e.04 624.2 Atrophy of female genital tract Female 26 295 11 genitourinary black 295, 26 74, 8 74, 4 73, 8 74, 6 0.0901 0.221 0.684 0.1648 1.09 0.709 1.69 -0.609 0.572 0.287 0.5419 0.544 0.177 1.67 0.081 0.488 0.868 0.06143 1.08 0.417 2.82 -0.113 0.535 0.832 0.07983 0.893 0.313 2.55 PRS_PLINK_1e.04 624.9 stress incontinence, female Female 917 7990 11 genitourinary black 7990, 917 1998, 240 1997, 230 1997, 226 1998, 221 -0.0351 0.0351 0.317 0.499 0.966 0.901 1.03 -0.0439 0.0975 0.652 0.1855 0.957 0.791 1.16 -0.0656 0.0977 0.502 0.2994 0.936 0.773 1.13 -0.0861 0.0983 0.381 0.419 0.918 0.757 1.11 PRS_PLINK_1e.04 625 Pain and other symptoms associated with female genital organs Female 3236 9699 11 genitourinary black 9699, 3236 2425, 850 2425, 755 2424, 807 2425, 823 -0.00806 0.0205 0.695 0.1583 0.992 0.953 1.03 -0.123 0.0579 0.0342 1.465 0.885 0.79 0.991 -0.0516 0.0572 0.367 0.4359 0.95 0.849 1.06 -0.0255 0.057 0.655 0.1838 0.975 0.872 1.09 PRS_PLINK_1e.04 625.1 Dyspareunia Female 782 7695 11 genitourinary black 7695, 782 1924, 224 1924, 170 1923, 185 1924, 203 -0.0314 0.0376 0.405 0.3929 0.969 0.9 1.04 -0.274 0.107 0.0103 1.988 0.761 0.617 0.937 -0.198 0.104 0.0571 1.244 0.82 0.669 1.01 -0.102 0.102 0.319 0.4959 0.903 0.74 1.1 PRS_PLINK_1e.04 626 Disorders of menstruation and other abnormal bleeding from female genital tract Female 3674 8719 11 genitourinary black 8719, 3674 2180, 955 2180, 884 2179, 926 2180, 909 -0.00651 0.0202 0.747 0.1268 0.994 0.955 1.03 -0.082 0.0565 0.147 0.8336 0.921 0.825 1.03 -0.0249 0.0559 0.656 0.1828 0.975 0.874 1.09 -0.0357 0.0562 0.526 0.2793 0.965 0.864 1.08 PRS_PLINK_1e.04 626.1 Irregular menstrual cycle/bleeding Female 2719 8506 11 genitourinary black 8506, 2719 2127, 690 2126, 651 2126, 707 2127, 671 0.00553 0.0226 0.806 0.09352 1.01 0.962 1.05 -0.0626 0.0635 0.324 0.4892 0.939 0.829 1.06 0.0298 0.0624 0.634 0.1982 1.03 0.912 1.16 -0.0108 0.0632 0.864 0.06325 0.989 0.874 1.12 PRS_PLINK_1e.04 626.11 Absent or infrequent menstruation Female 704 6082 11 genitourinary black 6082, 704 1521, 170 1520, 189 1520, 165 1521, 180 0.0218 0.0408 0.593 0.2267 1.02 0.943 1.11 0.118 0.112 0.295 0.5303 1.12 0.903 1.4 -0.0263 0.115 0.82 0.08642 0.974 0.777 1.22 0.0673 0.113 0.552 0.2581 1.07 0.857 1.34 PRS_PLINK_1e.04 626.12 Excessive or frequent menstruation Female 1305 7660 11 genitourinary black 7660, 1305 1915, 314 1915, 313 1915, 347 1915, 331 0.0292 0.0303 0.336 0.4737 1.03 0.97 1.09 7.96e-06 0.0862 1 3.199e-05 1 0.845 1.18 0.0971 0.0845 0.25 0.6012 1.1 0.934 1.3 0.0594 0.0852 0.485 0.3139 1.06 0.898 1.25 PRS_PLINK_1e.04 626.13 Irregular menstrual cycle Female 1201 7767 11 genitourinary black 7767, 1201 1942, 309 1942, 274 1941, 312 1942, 306 0.0181 0.0316 0.568 0.2456 1.02 0.957 1.08 -0.12 0.0895 0.179 0.7482 0.887 0.744 1.06 0.0122 0.0868 0.888 0.05145 1.01 0.854 1.2 0.00322 0.0874 0.971 0.01295 1 0.845 1.19 PRS_PLINK_1e.04 626.14 Irregular menstrual bleeding Female 601 6132 11 genitourinary black 6132, 601 1533, 171 1533, 137 1533, 151 1533, 142 -0.071 0.0427 0.0966 1.015 0.931 0.857 1.01 -0.221 0.12 0.0659 1.181 0.802 0.634 1.01 -0.113 0.117 0.333 0.4774 0.893 0.71 1.12 -0.184 0.119 0.123 0.9103 0.832 0.659 1.05 PRS_PLINK_1e.04 626.15 Infertility, female, associated with anovulation Female 287 2840 11 genitourinary black 2840, 287 710, 80 710, 79 710, 73 710, 55 -0.104 0.0626 0.0968 1.014 0.901 0.797 1.02 -0.0123 0.167 0.941 0.02632 0.988 0.712 1.37 -0.0935 0.17 0.583 0.2344 0.911 0.652 1.27 -0.388 0.182 0.033 1.482 0.678 0.475 0.969 PRS_PLINK_1e.04 626.2 Dysmenorrhea Female 943 6827 11 genitourinary black 6827, 943 1707, 254 1707, 218 1706, 219 1707, 252 -0.0202 0.0352 0.566 0.2472 0.98 0.915 1.05 -0.151 0.0987 0.126 0.8989 0.86 0.709 1.04 -0.151 0.0986 0.126 0.9008 0.86 0.709 1.04 0.00443 0.0958 0.963 0.01634 1 0.833 1.21 PRS_PLINK_1e.04 626.4 Premenstrual tension syndromes Female 224 2242 11 genitourinary black 2242, 224 561, 63 560, 52 560, 55 561, 54 -0.00962 0.0716 0.893 0.04913 0.99 0.861 1.14 -0.17 0.194 0.382 0.4183 0.844 0.577 1.23 -0.128 0.192 0.507 0.2952 0.88 0.604 1.28 -0.101 0.194 0.604 0.2191 0.904 0.618 1.32 PRS_PLINK_1e.04 626.8 Infertility, female Female 597 4973 11 genitourinary black 4973, 597 1244, 150 1243, 158 1243, 150 1243, 139 0.00772 0.0441 0.861 0.06503 1.01 0.924 1.1 0.0525 0.121 0.665 0.1774 1.05 0.831 1.34 0.0244 0.122 0.842 0.07464 1.02 0.806 1.3 -0.0599 0.124 0.63 0.2008 0.942 0.738 1.2 PRS_PLINK_1e.04 627 Menopausal and postmenopausal disorders Female 2056 7742 11 genitourinary black 7742, 2056 1936, 545 1935, 497 1935, 532 1936, 482 -0.0409 0.0254 0.107 0.9692 0.96 0.913 1.01 -0.107 0.0711 0.134 0.8739 0.899 0.782 1.03 -0.0382 0.0701 0.586 0.2324 0.963 0.839 1.1 -0.134 0.0717 0.0609 1.215 0.874 0.76 1.01 PRS_PLINK_1e.04 627.1 Postmenopausal bleeding Female 398 4469 11 genitourinary black 4469, 398 1118, 109 1117, 96 1117, 91 1117, 102 -0.0337 0.0529 0.525 0.2801 0.967 0.872 1.07 -0.12 0.146 0.411 0.3866 0.887 0.667 1.18 -0.183 0.147 0.214 0.6694 0.833 0.624 1.11 -0.0584 0.144 0.685 0.1645 0.943 0.712 1.25 PRS_PLINK_1e.04 627.2 Symptomatic menopause Female 1393 7036 11 genitourinary black 7036, 1393 1759, 365 1759, 328 1759, 360 1759, 340 -0.0379 0.0299 0.205 0.6878 0.963 0.908 1.02 -0.126 0.0844 0.135 0.87 0.881 0.747 1.04 -0.0241 0.0822 0.77 0.1136 0.976 0.831 1.15 -0.0854 0.0837 0.307 0.5123 0.918 0.779 1.08 PRS_PLINK_1e.04 627.21 Symptomatic artificial menopause Female 69 886 11 genitourinary black 886, 69 222, 11 221, 14 221, 26 222, 18 0.188 0.126 0.134 0.8718 1.21 0.944 1.54 0.227 0.392 0.562 0.2506 1.26 0.583 2.7 0.803 0.356 0.024 1.619 2.23 1.11 4.48 0.479 0.374 0.201 0.6968 1.61 0.775 3.36 PRS_PLINK_1e.04 627.22 Need for Hormone replacement therapy (postmenopausal) Female 139 1417 11 genitourinary black 1417, 139 355, 50 354, 36 354, 31 354, 22 -0.236 0.0907 0.00911 2.04 0.789 0.661 0.943 -0.323 0.23 0.16 0.7958 0.724 0.461 1.14 -0.472 0.239 0.0485 1.314 0.624 0.39 0.997 -0.832 0.262 0.0015 2.823 0.435 0.26 0.727 PRS_PLINK_1e.04 627.3 Postmenopausal atrophic vaginitis Female 404 4031 11 genitourinary black 4031, 404 1008, 116 1008, 89 1007, 106 1008, 93 -0.0478 0.053 0.367 0.4353 0.953 0.859 1.06 -0.256 0.147 0.082 1.086 0.774 0.58 1.03 -0.0974 0.142 0.491 0.3087 0.907 0.687 1.2 -0.245 0.146 0.0928 1.033 0.783 0.588 1.04 PRS_PLINK_1e.04 627.4 Premenopausal menorrhagia Female 187 2171 11 genitourinary black 2171, 187 543, 52 543, 43 542, 44 543, 48 -0.00486 0.0755 0.949 0.02288 0.995 0.858 1.15 -0.193 0.212 0.362 0.4407 0.825 0.545 1.25 -0.171 0.21 0.416 0.3812 0.843 0.558 1.27 -0.1 0.206 0.627 0.2025 0.905 0.604 1.36 PRS_PLINK_1e.04 627.5 Premature menopause and other ovarian failure Female 200 2033 11 genitourinary black 2033, 200 509, 61 508, 48 508, 52 508, 39 -0.093 0.0753 0.217 0.6643 0.911 0.786 1.06 -0.23 0.202 0.255 0.5936 0.795 0.535 1.18 -0.149 0.198 0.452 0.3452 0.862 0.585 1.27 -0.459 0.212 0.0304 1.517 0.632 0.417 0.958 PRS_PLINK_1e.04 628 Ovarian cyst Female 1129 8187 11 genitourinary black 8187, 1129 2047, 282 2047, 267 2046, 290 2047, 289 0.000816 0.0321 0.98 0.008896 1 0.94 1.07 -0.0638 0.0913 0.485 0.3147 0.938 0.785 1.12 0.0259 0.0897 0.773 0.1118 1.03 0.861 1.22 0.0394 0.0896 0.66 0.1804 1.04 0.873 1.24 PRS_PLINK_1e.04 634 Miscarriage; stillbirth Female 575 5635 12 pregnancy complications royalblue4 5635, 575 1409, 130 1409, 152 1408, 150 1409, 143 0.0701 0.045 0.119 0.9235 1.07 0.982 1.17 0.159 0.125 0.203 0.6919 1.17 0.918 1.5 0.138 0.125 0.271 0.5676 1.15 0.898 1.47 0.103 0.127 0.415 0.3817 1.11 0.865 1.42 PRS_PLINK_1e.04 634.1 Missed abortion/Hydatidiform mole Female 197 2018 12 pregnancy complications royalblue4 2018, 197 505, 56 504, 48 504, 52 505, 41 -0.0594 0.076 0.435 0.3618 0.942 0.812 1.09 -0.152 0.204 0.455 0.342 0.859 0.576 1.28 -0.045 0.202 0.823 0.08439 0.956 0.644 1.42 -0.316 0.212 0.137 0.8631 0.729 0.481 1.11 PRS_PLINK_1e.04 634.3 Ectopic pregnancy Female 88 836 12 pregnancy complications royalblue4 836, 88 209, 21 209, 21 209, 23 209, 23 0.11 0.115 0.342 0.4658 1.12 0.89 1.4 0.0559 0.321 0.862 0.06469 1.06 0.564 1.98 0.131 0.311 0.674 0.1714 1.14 0.619 2.1 0.128 0.31 0.68 0.1675 1.14 0.619 2.09 PRS_PLINK_1e.04 635 Hemorrhage during pregnancy; childbirth and postpartum Female 445 4192 12 pregnancy complications royalblue4 4192, 445 1048, 120 1048, 108 1048, 108 1048, 109 -0.0236 0.0507 0.642 0.1925 0.977 0.884 1.08 -0.108 0.139 0.439 0.3575 0.898 0.683 1.18 -0.0962 0.139 0.49 0.3099 0.908 0.691 1.19 -0.0804 0.139 0.563 0.2497 0.923 0.703 1.21 PRS_PLINK_1e.04 635.2 Antepartum hemorrhage, abruptio placentae, and placenta previa Female 287 2897 12 pregnancy complications royalblue4 2897, 287 725, 71 724, 66 724, 73 724, 77 0.0543 0.0634 0.392 0.4063 1.06 0.932 1.2 -0.0793 0.178 0.655 0.1835 0.924 0.652 1.31 0.0313 0.174 0.857 0.067 1.03 0.734 1.45 0.0901 0.172 0.599 0.2222 1.09 0.782 1.53 PRS_PLINK_1e.04 635.3 Placenta previa and abruptio placenta Female 241 2322 12 pregnancy complications royalblue4 2322, 241 581, 71 580, 61 580, 55 581, 54 -0.0681 0.0682 0.318 0.4976 0.934 0.817 1.07 -0.146 0.183 0.423 0.3736 0.864 0.604 1.24 -0.241 0.188 0.199 0.7004 0.786 0.544 1.14 -0.244 0.189 0.198 0.703 0.784 0.541 1.14 PRS_PLINK_1e.04 636 Early or threatened labor; hemorrhage in early pregnancy Female 841 5969 12 pregnancy complications royalblue4 5969, 841 1493, 218 1492, 194 1492, 194 1492, 234 0.0473 0.0374 0.207 0.6846 1.05 0.974 1.13 -0.108 0.106 0.308 0.5117 0.898 0.73 1.1 -0.119 0.105 0.258 0.5879 0.888 0.722 1.09 0.0852 0.101 0.4 0.3984 1.09 0.893 1.33 PRS_PLINK_1e.04 636.1 Threatened premature labor Female 295 3018 12 pregnancy complications royalblue4 3018, 295 755, 84 754, 64 754, 66 755, 80 0.00253 0.0618 0.967 0.01443 1 0.888 1.13 -0.244 0.172 0.157 0.8045 0.783 0.559 1.1 -0.231 0.172 0.178 0.7491 0.794 0.567 1.11 -0.0173 0.164 0.916 0.03818 0.983 0.713 1.35 PRS_PLINK_1e.04 636.2 Early onset of delivery Female 213 2214 12 pregnancy complications royalblue4 2214, 213 554, 56 553, 50 553, 41 554, 66 0.0718 0.0739 0.331 0.4805 1.07 0.93 1.24 -0.102 0.201 0.612 0.2133 0.903 0.608 1.34 -0.318 0.212 0.132 0.8785 0.727 0.48 1.1 0.16 0.19 0.399 0.3987 1.17 0.808 1.71 PRS_PLINK_1e.04 636.3 Hemorrhage in early pregnancy Female 337 3420 12 pregnancy complications royalblue4 3420, 337 855, 83 855, 79 855, 87 855, 88 0.0572 0.0584 0.327 0.4858 1.06 0.944 1.19 -0.0293 0.164 0.858 0.06636 0.971 0.704 1.34 0.0539 0.16 0.736 0.1331 1.06 0.771 1.44 0.0697 0.16 0.662 0.1791 1.07 0.784 1.47 PRS_PLINK_1e.04 636.8 Cervical incompetence Female 59 621 12 pregnancy complications royalblue4 621, 59 156, 19 155, 9 155, 15 155, 16 -0.0713 0.132 0.59 0.2292 0.931 0.719 1.21 -0.772 0.401 0.0544 1.264 0.462 0.211 1.01 -0.162 0.354 0.646 0.1896 0.85 0.425 1.7 -0.15 0.347 0.666 0.1765 0.861 0.436 1.7 PRS_PLINK_1e.04 637 Short gestation; low birth weight; and fetal growth retardation Both 41 480 12 pregnancy complications royalblue4 480, 41 120, 14 120, 10 120, 8 120, 9 -0.218 0.162 0.177 0.7508 0.804 0.586 1.1 -0.356 0.409 0.384 0.4152 0.7 0.314 1.56 -0.475 0.433 0.273 0.5646 0.622 0.266 1.45 -0.462 0.426 0.278 0.5564 0.63 0.273 1.45 PRS_PLINK_1e.04 642 Hypertension complicating pregnancy, childbirth, and the puerperium Female 295 4480 12 pregnancy complications royalblue4 4480, 295 1119, 95 1120, 70 1120, 62 1120, 68 -0.0993 0.0592 0.0936 1.029 0.905 0.806 1.02 -0.31 0.162 0.0553 1.257 0.733 0.534 1.01 -0.415 0.168 0.0133 1.875 0.661 0.476 0.917 -0.337 0.163 0.0393 1.405 0.714 0.519 0.984 PRS_PLINK_1e.04 642.1 Preeclampsia and eclampsia Female 151 2328 12 pregnancy complications royalblue4 2328, 151 582, 48 582, 39 582, 32 582, 32 -0.142 0.0854 0.0953 1.021 0.867 0.734 1.03 -0.201 0.22 0.359 0.4443 0.818 0.531 1.26 -0.41 0.232 0.0769 1.114 0.663 0.421 1.05 -0.379 0.231 0.101 0.9972 0.685 0.436 1.08 PRS_PLINK_1e.04 643 Excessive vomiting in pregnancy Female 189 2015 12 pregnancy complications royalblue4 2015, 189 504, 47 504, 44 503, 49 504, 49 0.0254 0.0768 0.741 0.1302 1.03 0.882 1.19 -0.0552 0.216 0.798 0.09799 0.946 0.62 1.44 0.0427 0.211 0.84 0.07583 1.04 0.69 1.58 0.0755 0.211 0.72 0.1424 1.08 0.713 1.63 PRS_PLINK_1e.04 643.1 Hyperemesis gravidarum Female 91 909 12 pregnancy complications royalblue4 909, 91 228, 25 227, 18 227, 21 227, 27 0.0626 0.11 0.571 0.2433 1.06 0.857 1.32 -0.249 0.314 0.428 0.3688 0.779 0.421 1.44 -0.154 0.306 0.614 0.212 0.857 0.471 1.56 0.117 0.287 0.683 0.1653 1.12 0.64 1.97 PRS_PLINK_1e.04 644 Anemia during pregnancy Female 173 1824 12 pregnancy complications royalblue4 1824, 173 456, 49 456, 40 456, 43 456, 41 -0.0232 0.0801 0.773 0.1121 0.977 0.835 1.14 -0.193 0.22 0.382 0.418 0.825 0.535 1.27 -0.126 0.217 0.562 0.2499 0.882 0.576 1.35 -0.167 0.22 0.446 0.3505 0.846 0.55 1.3 PRS_PLINK_1e.04 646 Other complications of pregnancy NEC Female 646 5208 12 pregnancy complications royalblue4 5208, 646 1301, 183 1302, 156 1302, 129 1302, 178 0.00594 0.0423 0.888 0.05144 1.01 0.926 1.09 -0.154 0.116 0.185 0.7332 0.858 0.684 1.08 -0.347 0.122 0.00436 2.361 0.707 0.557 0.897 -0.0101 0.112 0.929 0.0322 0.99 0.794 1.23 PRS_PLINK_1e.04 647 Infectious and parasitic complications affecting pregnancy Female 163 1627 12 pregnancy complications royalblue4 1627, 163 406, 42 407, 43 406, 38 407, 40 0.00927 0.0813 0.909 0.04134 1.01 0.861 1.18 0.0183 0.225 0.935 0.02903 1.02 0.655 1.58 -0.0751 0.231 0.745 0.1276 0.928 0.589 1.46 -0.0102 0.229 0.964 0.01578 0.99 0.632 1.55 PRS_PLINK_1e.04 647.1 Infections of genitourinary tract during pregnancy Female 169 1795 12 pregnancy complications royalblue4 1795, 169 449, 46 449, 48 448, 37 449, 38 -0.048 0.0824 0.56 0.2515 0.953 0.811 1.12 0.0539 0.216 0.803 0.09534 1.06 0.691 1.61 -0.191 0.227 0.401 0.397 0.826 0.529 1.29 -0.139 0.228 0.544 0.2647 0.87 0.556 1.36 PRS_PLINK_1e.04 647.3 Major puerperal infection Female 54 518 12 pregnancy complications royalblue4 518, 54 130, 11 129, 19 129, 10 130, 14 0.0473 0.148 0.75 0.1252 1.05 0.784 1.4 0.519 0.384 0.177 0.7523 1.68 0.791 3.57 -0.077 0.427 0.857 0.06705 0.926 0.401 2.14 0.294 0.404 0.467 0.331 1.34 0.608 2.96 PRS_PLINK_1e.04 649 Other conditions or status of the mother complicating pregnancy, childbirth, or the puerperium Female 981 6125 12 pregnancy complications royalblue4 6125, 981 1532, 283 1531, 238 1531, 210 1531, 249 -0.018 0.0347 0.605 0.2181 0.982 0.918 1.05 -0.167 0.0957 0.0805 1.094 0.846 0.701 1.02 -0.293 0.0986 0.00295 2.531 0.746 0.615 0.905 -0.107 0.0947 0.259 0.5871 0.899 0.746 1.08 PRS_PLINK_1e.04 649.1 Diabetes or abnormal glucose tolerance complicating pregnancy Female 345 3837 12 pregnancy complications royalblue4 3837, 345 960, 76 959, 89 959, 84 959, 96 0.114 0.0579 0.048 1.319 1.12 1 1.26 0.172 0.163 0.292 0.5348 1.19 0.863 1.63 0.118 0.166 0.475 0.3233 1.13 0.813 1.56 0.296 0.162 0.0684 1.165 1.34 0.978 1.85 PRS_PLINK_1e.04 653 Problems associated with amniotic cavity and membranes Female 483 4270 12 pregnancy complications royalblue4 4270, 483 1067, 132 1067, 116 1067, 122 1068, 113 -0.0416 0.0485 0.391 0.4079 0.959 0.872 1.05 -0.145 0.135 0.28 0.5522 0.865 0.664 1.13 -0.092 0.133 0.488 0.3113 0.912 0.703 1.18 -0.154 0.135 0.253 0.5972 0.857 0.658 1.12 PRS_PLINK_1e.04 654.1 Abnormality of organs and soft tissues of pelvis complicating pregnancy, childbirth, or the puerperium Female 145 1644 12 pregnancy complications royalblue4 1644, 145 410, 37 411, 37 411, 27 411, 44 0.1 0.0888 0.259 0.5866 1.11 0.929 1.32 -0.00821 0.239 0.973 0.01206 0.992 0.621 1.58 -0.297 0.258 0.249 0.6035 0.743 0.449 1.23 0.175 0.231 0.449 0.3479 1.19 0.757 1.87 PRS_PLINK_1e.04 654.2 Rhesus isoimmunization in pregnancy Female 162 1589 12 pregnancy complications royalblue4 1589, 162 398, 55 397, 31 397, 34 397, 42 -0.0885 0.0829 0.285 0.5447 0.915 0.778 1.08 -0.572 0.233 0.014 1.853 0.564 0.358 0.891 -0.492 0.227 0.0306 1.515 0.612 0.392 0.955 -0.249 0.216 0.248 0.605 0.779 0.511 1.19 PRS_PLINK_1e.04 655 Known or suspected fetal abnormality affecting management of mother Female 1250 7332 12 pregnancy complications royalblue4 7332, 1250 1833, 333 1833, 304 1833, 289 1833, 323 0.00597 0.031 0.847 0.0719 1.01 0.947 1.07 -0.0969 0.0865 0.263 0.5807 0.908 0.766 1.08 -0.141 0.0874 0.106 0.975 0.868 0.732 1.03 -0.0158 0.0852 0.853 0.0693 0.984 0.833 1.16 PRS_PLINK_1e.04 655.1 Abnormality in fetal heart rate or rhythm Female 481 4371 12 pregnancy complications royalblue4 4371, 481 1093, 131 1093, 128 1092, 98 1093, 123 0.00204 0.0482 0.966 0.01489 1 0.912 1.1 -0.0253 0.131 0.848 0.07177 0.975 0.754 1.26 -0.304 0.14 0.0305 1.515 0.738 0.56 0.972 -0.0515 0.133 0.698 0.1563 0.95 0.733 1.23 PRS_PLINK_1e.04 656 Other perinatal conditions of fetus or newborn Both 652 5224 12 pregnancy complications royalblue4 5224, 652 1305, 169 1306, 168 1306, 147 1306, 168 0.017 0.0418 0.684 0.1648 1.02 0.937 1.1 0.0106 0.116 0.928 0.03268 1.01 0.805 1.27 -0.121 0.12 0.312 0.5052 0.886 0.701 1.12 0.0191 0.116 0.869 0.06085 1.02 0.812 1.28 PRS_PLINK_1e.04 656.2 Respiratory conditions of fetus and newborn Both 21 326 12 pregnancy complications royalblue4 326, 21 82, 4 81, 4 81, 6 82, 7 0.288 0.227 0.204 0.6906 1.33 0.855 2.08 -0.0686 0.611 0.911 0.04068 0.934 0.282 3.09 0.392 0.593 0.509 0.2931 1.48 0.462 4.73 0.514 0.579 0.375 0.4265 1.67 0.537 5.2 PRS_PLINK_1e.04 669 Complications of labor and delivery NEC Female 662 5331 12 pregnancy complications royalblue4 5331, 662 1332, 197 1333, 152 1332, 138 1333, 175 -0.0228 0.0416 0.583 0.2343 0.977 0.901 1.06 -0.255 0.115 0.0266 1.575 0.775 0.619 0.971 -0.362 0.118 0.00215 2.667 0.697 0.553 0.878 -0.106 0.111 0.34 0.4686 0.899 0.723 1.12 PRS_PLINK_1e.04 671 Venous/cerebrovascular complications embolism in pregnancy and the puerperium Female 136 1579 12 pregnancy complications royalblue4 1579, 136 395, 53 395, 26 394, 22 395, 34 -0.257 0.0844 0.0023 2.639 0.773 0.655 0.912 -0.723 0.248 0.00353 2.453 0.485 0.299 0.789 -0.825 0.258 0.00136 2.868 0.438 0.264 0.726 -0.388 0.229 0.0906 1.043 0.679 0.433 1.06 PRS_PLINK_1e.04 674 Other complications of the puerperium NEC Female 103 1272 12 pregnancy complications royalblue4 1272, 103 318, 29 318, 28 318, 17 318, 29 -0.0403 0.104 0.699 0.1558 0.96 0.783 1.18 -0.0508 0.271 0.851 0.06992 0.951 0.559 1.62 -0.477 0.304 0.117 0.9312 0.621 0.342 1.13 0.02 0.269 0.941 0.02644 1.02 0.602 1.73 PRS_PLINK_1e.04 676 Other disorders of the breast associated with childbirth and disorders of lactation Female 160 1486 12 pregnancy complications royalblue4 1486, 160 372, 46 371, 38 371, 36 372, 40 0.0148 0.0857 0.863 0.06418 1.01 0.858 1.2 -0.188 0.229 0.412 0.385 0.829 0.529 1.3 -0.158 0.235 0.503 0.2983 0.854 0.538 1.36 -0.0723 0.229 0.752 0.1238 0.93 0.594 1.46 PRS_PLINK_1e.04 681 Superficial cellulitis and abscess Both 2252 20261 13 dermatologic firebrick 20261, 2252 5065, 520 5065, 564 5065, 585 5065, 583 0.0294 0.0222 0.187 0.7283 1.03 0.986 1.08 0.0864 0.064 0.177 0.7522 1.09 0.962 1.24 0.123 0.0636 0.0533 1.274 1.13 0.998 1.28 0.113 0.0636 0.0765 1.116 1.12 0.988 1.27 PRS_PLINK_1e.04 681.1 Cellulitis and abscess of fingers/toes Both 378 5513 13 dermatologic firebrick 5513, 378 1379, 82 1378, 95 1378, 111 1378, 90 0.0179 0.0526 0.734 0.1343 1.02 0.918 1.13 0.169 0.154 0.275 0.5609 1.18 0.875 1.6 0.335 0.15 0.0253 1.597 1.4 1.04 1.88 0.108 0.156 0.489 0.3105 1.11 0.82 1.51 PRS_PLINK_1e.04 681.2 Cellulitis and abscess of face/neck Both 362 4788 13 dermatologic firebrick 4788, 362 1197, 95 1197, 74 1197, 105 1197, 88 0.00917 0.0551 0.868 0.06158 1.01 0.906 1.12 -0.247 0.159 0.121 0.9185 0.781 0.572 1.07 0.117 0.146 0.426 0.3709 1.12 0.843 1.5 -0.0651 0.152 0.669 0.1744 0.937 0.695 1.26 PRS_PLINK_1e.04 681.3 Cellulitis and abscess of arm/hand Both 553 9381 13 dermatologic firebrick 9381, 553 2346, 119 2345, 143 2345, 148 2345, 143 0.0537 0.044 0.222 0.6534 1.06 0.968 1.15 0.185 0.127 0.146 0.8368 1.2 0.938 1.54 0.215 0.126 0.0877 1.057 1.24 0.969 1.59 0.184 0.127 0.147 0.8337 1.2 0.938 1.54 PRS_PLINK_1e.04 681.5 Cellulitis and abscess of leg, except foot Both 565 9722 13 dermatologic firebrick 9722, 565 2431, 126 2430, 137 2430, 147 2431, 155 0.062 0.0434 0.152 0.8168 1.06 0.977 1.16 0.0932 0.126 0.46 0.3376 1.1 0.857 1.41 0.156 0.124 0.21 0.6786 1.17 0.916 1.49 0.216 0.123 0.078 1.108 1.24 0.976 1.58 PRS_PLINK_1e.04 681.6 Cellulitis and abscess of foot, toe Both 438 7745 13 dermatologic firebrick 7745, 438 1937, 95 1936, 111 1936, 115 1936, 117 0.0554 0.0492 0.261 0.5839 1.06 0.96 1.16 0.158 0.143 0.268 0.5724 1.17 0.886 1.55 0.181 0.141 0.199 0.7005 1.2 0.909 1.58 0.208 0.141 0.139 0.8576 1.23 0.935 1.62 PRS_PLINK_1e.04 681.7 Cellulitis and abscess of trunk Both 517 7747 13 dermatologic firebrick 7747, 517 1937, 136 1937, 149 1936, 118 1937, 114 -0.102 0.0452 0.024 1.619 0.903 0.826 0.987 0.0908 0.122 0.458 0.3392 1.1 0.862 1.39 -0.149 0.129 0.247 0.6068 0.861 0.669 1.11 -0.179 0.13 0.169 0.7719 0.836 0.648 1.08 PRS_PLINK_1e.04 686 Other local infections of skin and subcutaneous tissue Both 752 10533 13 dermatologic firebrick 10533, 752 2634, 172 2633, 195 2633, 180 2633, 205 0.031 0.0377 0.41 0.387 1.03 0.958 1.11 0.124 0.108 0.251 0.6011 1.13 0.916 1.4 0.0448 0.11 0.683 0.1659 1.05 0.844 1.3 0.173 0.107 0.104 0.983 1.19 0.965 1.47 PRS_PLINK_1e.04 686.1 Carbuncle and furuncle Both 222 2978 13 dermatologic firebrick 2978, 222 745, 39 744, 72 744, 56 745, 55 0.116 0.0699 0.0976 1.011 1.12 0.979 1.29 0.621 0.203 0.00227 2.645 1.86 1.25 2.77 0.34 0.211 0.108 0.9672 1.4 0.928 2.13 0.354 0.212 0.0946 1.024 1.43 0.941 2.16 PRS_PLINK_1e.04 686.2 Impetigo Both 203 2206 13 dermatologic firebrick 2206, 203 552, 49 551, 53 551, 38 552, 63 0.032 0.0723 0.659 0.1814 1.03 0.896 1.19 0.113 0.205 0.581 0.2357 1.12 0.749 1.67 -0.219 0.221 0.321 0.4933 0.803 0.521 1.24 0.26 0.197 0.187 0.7288 1.3 0.882 1.91 PRS_PLINK_1e.04 686.3 Pilonidal cyst Both 90 956 13 dermatologic firebrick 956, 90 239, 17 239, 24 239, 25 239, 24 0.11 0.108 0.309 0.5102 1.12 0.903 1.38 0.354 0.317 0.264 0.5783 1.42 0.766 2.65 0.413 0.318 0.194 0.7125 1.51 0.811 2.82 0.324 0.318 0.31 0.5092 1.38 0.74 2.58 PRS_PLINK_1e.04 686.4 Pyogenic granuloma Both 65 835 13 dermatologic firebrick 835, 65 209, 18 209, 12 208, 14 209, 21 0.134 0.129 0.299 0.5242 1.14 0.888 1.47 -0.376 0.367 0.306 0.5145 0.687 0.334 1.41 -0.186 0.357 0.603 0.2194 0.831 0.413 1.67 0.102 0.329 0.756 0.1216 1.11 0.581 2.11 PRS_PLINK_1e.04 686.5 Pyoderma Both 20 293 13 dermatologic firebrick 293, 20 74, 3 73, 7 73, 8 73, 2 -0.0957 0.218 0.661 0.18 0.909 0.593 1.39 0.841 0.641 0.19 0.7222 2.32 0.66 8.16 1.04 0.616 0.0902 1.045 2.84 0.849 9.49 -0.378 0.721 0.6 0.2219 0.685 0.167 2.81 PRS_PLINK_1e.04 687 Symptoms affecting skin Both 633 7566 13 dermatologic firebrick 7566, 633 1892, 173 1891, 139 1891, 169 1892, 152 -0.0197 0.0406 0.627 0.2025 0.98 0.905 1.06 -0.213 0.118 0.0711 1.148 0.808 0.641 1.02 -0.0222 0.112 0.844 0.07383 0.978 0.785 1.22 -0.127 0.115 0.271 0.5667 0.881 0.703 1.1 PRS_PLINK_1e.04 687.1 Rash and other nonspecific skin eruption Both 2831 18287 13 dermatologic firebrick 18287, 2831 4572, 681 4572, 637 4571, 739 4572, 774 0.0468 0.0204 0.0222 1.654 1.05 1.01 1.09 -0.0733 0.0594 0.217 0.6642 0.929 0.827 1.04 0.0798 0.0575 0.166 0.781 1.08 0.968 1.21 0.127 0.057 0.0261 1.584 1.14 1.02 1.27 PRS_PLINK_1e.04 687.3 Changes in skin texture Both 135 1772 13 dermatologic firebrick 1772, 135 443, 31 443, 29 443, 38 443, 37 0.11 0.0879 0.212 0.6735 1.12 0.939 1.33 -0.0496 0.26 0.849 0.07127 0.952 0.572 1.58 0.166 0.245 0.497 0.3037 1.18 0.731 1.91 0.184 0.247 0.455 0.3416 1.2 0.741 1.95 PRS_PLINK_1e.04 687.4 Disturbance of skin sensation Both 2587 17906 13 dermatologic firebrick 17906, 2587 4477, 683 4476, 624 4476, 632 4477, 647 -0.0196 0.021 0.352 0.4535 0.981 0.941 1.02 -0.093 0.0594 0.117 0.9316 0.911 0.811 1.02 -0.0846 0.0593 0.154 0.8133 0.919 0.818 1.03 -0.062 0.0589 0.293 0.5336 0.94 0.837 1.05 PRS_PLINK_1e.04 689 Disorder of skin and subcutaneous tissue NOS Both 3702 19637 13 dermatologic firebrick 19637, 3702 4910, 910 4909, 863 4909, 985 4909, 943 0.0073 0.0181 0.687 0.1629 1.01 0.972 1.04 -0.0566 0.0522 0.278 0.5554 0.945 0.853 1.05 0.0738 0.0508 0.146 0.8346 1.08 0.975 1.19 0.0285 0.0513 0.578 0.2382 1.03 0.931 1.14 PRS_PLINK_1e.04 690 Erythematosquamous dermatosis Both 1924 14827 13 dermatologic firebrick 14827, 1924 3707, 492 3707, 448 3706, 494 3707, 490 -0.00361 0.0244 0.883 0.05427 0.996 0.95 1.05 -0.104 0.0699 0.136 0.8677 0.901 0.786 1.03 -0.00652 0.0684 0.924 0.0343 0.993 0.869 1.14 -0.0163 0.0684 0.812 0.0907 0.984 0.86 1.13 PRS_PLINK_1e.04 690.1 Seborrheic dermatitis Both 1919 14803 13 dermatologic firebrick 14803, 1919 3701, 491 3701, 447 3700, 493 3701, 488 -0.00444 0.0244 0.856 0.06764 0.996 0.949 1.04 -0.105 0.0699 0.132 0.8778 0.9 0.785 1.03 -0.00653 0.0685 0.924 0.03429 0.993 0.869 1.14 -0.0182 0.0685 0.79 0.1022 0.982 0.859 1.12 PRS_PLINK_1e.04 691 Congenital anomalies of skin Both 255 2909 13 dermatologic firebrick 2909, 255 728, 75 727, 66 727, 64 727, 50 -0.136 0.0659 0.0392 1.407 0.873 0.767 0.993 -0.119 0.175 0.497 0.3034 0.888 0.631 1.25 -0.16 0.176 0.365 0.4377 0.853 0.604 1.2 -0.408 0.188 0.0296 1.529 0.665 0.46 0.96 PRS_PLINK_1e.04 691.3 Congenital pigmentary anomalies of skin Both 31 380 13 dermatologic firebrick 380, 31 95, 12 95, 5 95, 8 95, 6 -0.29 0.192 0.132 0.8802 0.749 0.514 1.09 -0.824 0.525 0.116 0.9348 0.439 0.157 1.23 -0.442 0.49 0.367 0.4356 0.643 0.246 1.68 -0.774 0.509 0.129 0.891 0.461 0.17 1.25 PRS_PLINK_1e.04 694 Dyschromia and Vitiligo Both 797 8369 13 dermatologic firebrick 8369, 797 2093, 188 2092, 192 2092, 215 2092, 202 0.0324 0.0369 0.379 0.4209 1.03 0.961 1.11 0.0132 0.107 0.902 0.04484 1.01 0.822 1.25 0.131 0.104 0.207 0.6842 1.14 0.93 1.4 0.0678 0.106 0.521 0.2832 1.07 0.87 1.32 PRS_PLINK_1e.04 694.1 Vitiligo Both 54 635 13 dermatologic firebrick 635, 54 159, 10 159, 14 158, 16 159, 14 0.118 0.135 0.381 0.4192 1.13 0.864 1.47 0.354 0.41 0.387 0.412 1.43 0.638 3.18 0.455 0.397 0.251 0.6 1.58 0.724 3.43 0.605 0.424 0.154 0.8138 1.83 0.798 4.2 PRS_PLINK_1e.04 694.2 Other dyschromia Both 732 7558 13 dermatologic firebrick 7558, 732 1890, 181 1889, 174 1889, 194 1890, 183 0.0167 0.0386 0.665 0.1773 1.02 0.943 1.1 -0.0458 0.111 0.679 0.1681 0.955 0.769 1.19 0.0654 0.108 0.545 0.2639 1.07 0.864 1.32 0.00598 0.109 0.956 0.01934 1.01 0.812 1.25 PRS_PLINK_1e.04 694.3 Vascular disorders of skin Both 23 393 13 dermatologic firebrick 393, 23 99, 3 98, 5 98, 6 98, 9 0.351 0.202 0.0818 1.087 1.42 0.957 2.11 0.474 0.649 0.465 0.3325 1.61 0.45 5.74 0.583 0.613 0.342 0.4666 1.79 0.539 5.95 1.4 0.629 0.0257 1.589 4.07 1.19 14 PRS_PLINK_1e.04 695 Erythematous conditions Both 1538 14790 13 dermatologic firebrick 14790, 1538 3697, 374 3697, 367 3697, 417 3698, 380 0.0215 0.027 0.426 0.3705 1.02 0.969 1.08 -0.0279 0.0773 0.718 0.1439 0.972 0.836 1.13 0.104 0.075 0.165 0.7816 1.11 0.958 1.29 0.0117 0.0766 0.878 0.05637 1.01 0.871 1.18 PRS_PLINK_1e.04 695.1 Toxic erythema Both 30 353 13 dermatologic firebrick 353, 30 89, 10 88, 7 88, 7 88, 6 -0.082 0.187 0.661 0.1798 0.921 0.639 1.33 -0.457 0.494 0.355 0.4502 0.633 0.241 1.67 -0.288 0.478 0.547 0.2624 0.75 0.294 1.91 -0.365 0.511 0.474 0.324 0.694 0.255 1.89 PRS_PLINK_1e.04 695.2 Bullous dermatoses Both 27 289 13 dermatologic firebrick 289, 27 73, 7 72, 5 72, 6 72, 9 0.0637 0.192 0.741 0.1304 1.07 0.731 1.55 -0.542 0.61 0.374 0.4267 0.582 0.176 1.92 0.152 0.559 0.785 0.105 1.16 0.39 3.48 0.223 0.499 0.655 0.1837 1.25 0.47 3.32 PRS_PLINK_1e.04 695.3 Rosacea Both 710 7995 13 dermatologic firebrick 7995, 710 1998, 162 1999, 179 1998, 179 1999, 190 0.0493 0.0392 0.209 0.6804 1.05 0.973 1.13 0.101 0.113 0.373 0.4285 1.11 0.886 1.38 0.103 0.113 0.36 0.4433 1.11 0.889 1.38 0.167 0.111 0.134 0.8742 1.18 0.95 1.47 PRS_PLINK_1e.04 695.4 Lupus (localized and systemic) Both 269 3547 13 dermatologic firebrick 3547, 269 886, 73 887, 57 886, 85 887, 54 -0.0277 0.0624 0.657 0.1825 0.973 0.861 1.1 -0.279 0.181 0.123 0.9092 0.757 0.531 1.08 0.157 0.165 0.339 0.4693 1.17 0.848 1.62 -0.302 0.183 0.0993 1.003 0.739 0.516 1.06 PRS_PLINK_1e.04 695.41 Cutaneous lupus erythematosus Both 102 1350 13 dermatologic firebrick 1350, 102 338, 36 337, 17 337, 30 338, 19 -0.106 0.0987 0.282 0.5493 0.899 0.741 1.09 -0.781 0.296 0.00832 2.08 0.458 0.256 0.818 -0.18 0.254 0.478 0.3208 0.835 0.508 1.37 -0.589 0.286 0.0396 1.403 0.555 0.317 0.972 PRS_PLINK_1e.04 695.42 Systemic lupus erythematosus Both 256 3373 13 dermatologic firebrick 3373, 256 843, 69 843, 55 843, 81 843, 51 -0.0298 0.0639 0.641 0.1932 0.971 0.856 1.1 -0.256 0.185 0.166 0.7803 0.774 0.539 1.11 0.158 0.169 0.348 0.4578 1.17 0.841 1.63 -0.301 0.188 0.11 0.96 0.74 0.511 1.07 PRS_PLINK_1e.04 695.7 Prurigo and Lichen Both 232 2639 13 dermatologic firebrick 2639, 232 660, 55 660, 60 659, 56 660, 61 0.0418 0.0693 0.546 0.2625 1.04 0.91 1.19 0.105 0.192 0.584 0.2336 1.11 0.763 1.62 0.0249 0.195 0.898 0.04655 1.03 0.7 1.5 0.0939 0.191 0.624 0.2049 1.1 0.755 1.6 PRS_PLINK_1e.04 695.8 Other specified erythematous conditions Both 256 3650 13 dermatologic firebrick 3650, 256 913, 57 912, 56 912, 80 913, 63 0.0641 0.0656 0.329 0.4831 1.07 0.938 1.21 -0.00195 0.192 0.992 0.003546 0.998 0.686 1.45 0.379 0.178 0.0332 1.479 1.46 1.03 2.07 0.11 0.187 0.556 0.2552 1.12 0.774 1.61 PRS_PLINK_1e.04 695.81 Erythema nodosum Both 34 340 13 dermatologic firebrick 340, 34 85, 6 85, 10 85, 8 85, 10 0.097 0.189 0.608 0.2161 1.1 0.761 1.6 0.566 0.535 0.29 0.537 1.76 0.617 5.02 0.312 0.519 0.548 0.2614 1.37 0.494 3.78 0.743 0.526 0.158 0.8015 2.1 0.75 5.89 PRS_PLINK_1e.04 695.9 Unspecified erythematous condition Both 203 3007 13 dermatologic firebrick 3007, 203 752, 43 752, 59 751, 47 752, 54 0.0523 0.0748 0.484 0.3149 1.05 0.91 1.22 0.304 0.205 0.138 0.8592 1.36 0.907 2.03 0.0943 0.214 0.659 0.1812 1.1 0.723 1.67 0.25 0.208 0.229 0.6411 1.28 0.855 1.93 PRS_PLINK_1e.04 696 Psoriasis and related disorders Both 570 6794 13 dermatologic firebrick 6794, 570 1699, 129 1698, 137 1698, 143 1699, 161 0.0764 0.044 0.0824 1.084 1.08 0.99 1.18 0.0604 0.127 0.633 0.1983 1.06 0.829 1.36 0.117 0.126 0.353 0.4528 1.12 0.879 1.44 0.221 0.123 0.071 1.149 1.25 0.981 1.59 PRS_PLINK_1e.04 696.3 Pityriasis Both 60 588 13 dermatologic firebrick 588, 60 147, 15 147, 12 147, 21 147, 12 -0.0574 0.134 0.668 0.1749 0.944 0.726 1.23 -0.26 0.397 0.512 0.2904 0.771 0.354 1.68 0.369 0.351 0.293 0.5335 1.45 0.727 2.88 -0.166 0.389 0.67 0.1742 0.847 0.395 1.82 PRS_PLINK_1e.04 696.4 Psoriasis Both 509 6233 13 dermatologic firebrick 6233, 509 1559, 112 1558, 125 1558, 121 1558, 151 0.0992 0.0467 0.0337 1.472 1.1 1.01 1.21 0.11 0.134 0.414 0.3835 1.12 0.858 1.45 0.0841 0.135 0.533 0.2732 1.09 0.835 1.42 0.296 0.129 0.0219 1.66 1.34 1.04 1.73 PRS_PLINK_1e.04 696.41 Psoriasis vulgaris Both 463 5691 13 dermatologic firebrick 5691, 463 1423, 100 1423, 115 1422, 111 1423, 137 0.11 0.0489 0.0242 1.616 1.12 1.01 1.23 0.142 0.141 0.312 0.5064 1.15 0.875 1.52 0.115 0.142 0.415 0.3816 1.12 0.85 1.48 0.312 0.136 0.0219 1.661 1.37 1.05 1.78 PRS_PLINK_1e.04 696.42 Psoriatic arthropathy Both 105 1364 13 dermatologic firebrick 1364, 105 341, 23 341, 25 341, 23 341, 34 0.176 0.103 0.0866 1.062 1.19 0.975 1.46 0.107 0.292 0.715 0.1458 1.11 0.628 1.97 0.0305 0.297 0.918 0.03709 1.03 0.576 1.85 0.385 0.276 0.163 0.787 1.47 0.855 2.53 PRS_PLINK_1e.04 697 Sarcoidosis Both 112 1453 13 dermatologic firebrick 1453, 112 364, 33 363, 29 363, 26 363, 24 -0.0769 0.0999 0.441 0.3552 0.926 0.761 1.13 -0.0748 0.26 0.774 0.1115 0.928 0.558 1.54 -0.221 0.265 0.404 0.3937 0.801 0.477 1.35 -0.317 0.274 0.247 0.6071 0.729 0.426 1.25 PRS_PLINK_1e.04 698 Pruritus and related conditions Both 925 11171 13 dermatologic firebrick 11171, 925 2792, 244 2793, 210 2792, 223 2793, 248 -0.00998 0.0346 0.773 0.112 0.99 0.925 1.06 -0.152 0.0977 0.119 0.9234 0.859 0.709 1.04 -0.0848 0.0963 0.379 0.4218 0.919 0.761 1.11 0.0265 0.094 0.778 0.1089 1.03 0.854 1.23 PRS_PLINK_1e.04 700 Corns and callosities Both 324 4527 13 dermatologic firebrick 4527, 324 1132, 84 1132, 83 1131, 88 1132, 69 -0.0483 0.058 0.405 0.3925 0.953 0.851 1.07 0.0195 0.16 0.903 0.04447 1.02 0.746 1.39 0.0484 0.158 0.759 0.1198 1.05 0.77 1.43 -0.169 0.167 0.31 0.5091 0.844 0.609 1.17 PRS_PLINK_1e.04 701 Other hypertrophic and atrophic conditions of skin Both 3267 19749 13 dermatologic firebrick 19749, 3267 4937, 779 4937, 823 4937, 815 4937, 850 0.0259 0.0191 0.175 0.7564 1.03 0.989 1.07 0.0528 0.0544 0.331 0.48 1.05 0.948 1.17 0.035 0.0545 0.521 0.2834 1.04 0.931 1.15 0.076 0.054 0.159 0.7984 1.08 0.971 1.2 PRS_PLINK_1e.04 701.1 Keratoderma, acquired Both 188 2326 13 dermatologic firebrick 2326, 188 582, 48 581, 44 581, 48 582, 48 -0.0675 0.0749 0.368 0.4347 0.935 0.807 1.08 -0.0977 0.213 0.647 0.1893 0.907 0.597 1.38 0.0299 0.21 0.887 0.05232 1.03 0.683 1.55 0.0361 0.209 0.863 0.06401 1.04 0.688 1.56 PRS_PLINK_1e.04 701.2 Scar conditions and fibrosis of skin Both 1052 10612 13 dermatologic firebrick 10612, 1052 2652, 269 2653, 255 2653, 255 2653, 273 0.0131 0.0325 0.688 0.1627 1.01 0.951 1.08 -0.0493 0.0914 0.59 0.2292 0.952 0.796 1.14 -0.0518 0.0914 0.571 0.2431 0.95 0.794 1.14 0.0205 0.0901 0.82 0.08604 1.02 0.856 1.22 PRS_PLINK_1e.04 701.3 Circumscribed scleroderma Both 216 2564 13 dermatologic firebrick 2564, 216 641, 51 641, 48 641, 57 641, 60 0.0965 0.0705 0.171 0.7668 1.1 0.959 1.26 -0.0502 0.206 0.807 0.09299 0.951 0.635 1.42 0.132 0.198 0.506 0.2955 1.14 0.773 1.68 0.182 0.196 0.354 0.4512 1.2 0.817 1.76 PRS_PLINK_1e.04 701.4 Keloid scar Both 329 3257 13 dermatologic firebrick 3257, 329 814, 77 814, 92 814, 78 814, 82 0.0229 0.0584 0.695 0.1581 1.02 0.912 1.15 0.186 0.161 0.248 0.6058 1.2 0.879 1.65 -0.000649 0.167 0.997 0.001351 0.999 0.721 1.39 0.055 0.165 0.738 0.1318 1.06 0.765 1.46 PRS_PLINK_1e.04 701.5 Abnormal granulation tissue Both 158 1906 13 dermatologic firebrick 1906, 158 477, 36 476, 59 476, 33 477, 30 -0.0784 0.0823 0.341 0.4678 0.925 0.787 1.09 0.527 0.219 0.016 1.796 1.69 1.1 2.6 -0.0965 0.244 0.692 0.1598 0.908 0.563 1.46 -0.193 0.252 0.444 0.3523 0.825 0.503 1.35 PRS_PLINK_1e.04 702 Degenerative skin conditions and other dermatoses Both 2462 13947 13 dermatologic firebrick 13947, 2462 3486, 637 3487, 574 3486, 652 3487, 599 -0.0174 0.0223 0.434 0.3626 0.983 0.941 1.03 -0.118 0.0638 0.064 1.194 0.889 0.784 1.01 0.0141 0.0621 0.82 0.0862 1.01 0.898 1.15 -0.0718 0.0631 0.255 0.594 0.931 0.822 1.05 PRS_PLINK_1e.04 702.1 Actinic keratosis Both 1314 10566 13 dermatologic firebrick 10566, 1314 2642, 355 2641, 293 2641, 351 2642, 315 -0.0341 0.0293 0.246 0.6099 0.967 0.913 1.02 -0.211 0.0843 0.0122 1.913 0.809 0.686 0.955 -0.0219 0.0806 0.786 0.1046 0.978 0.835 1.15 -0.129 0.0826 0.119 0.9238 0.879 0.748 1.03 PRS_PLINK_1e.04 702.2 Seborrheic keratosis Both 1959 14035 13 dermatologic firebrick 14035, 1959 3509, 502 3509, 457 3508, 518 3509, 482 -0.0195 0.0243 0.423 0.3737 0.981 0.935 1.03 -0.111 0.0698 0.11 0.9567 0.895 0.78 1.03 0.0147 0.0679 0.828 0.08173 1.01 0.888 1.16 -0.0525 0.0688 0.446 0.3508 0.949 0.829 1.09 PRS_PLINK_1e.04 702.4 Degenerative skin disorders Both 40 427 13 dermatologic firebrick 427, 40 107, 8 107, 10 106, 11 107, 11 0.0871 0.16 0.587 0.2312 1.09 0.797 1.49 0.184 0.473 0.697 0.1567 1.2 0.476 3.04 0.444 0.466 0.341 0.4667 1.56 0.625 3.89 0.424 0.45 0.347 0.4597 1.53 0.632 3.69 PRS_PLINK_1e.04 703 Diseases of nail, NOS Both 486 6396 13 dermatologic firebrick 6396, 486 1598, 112 1599, 124 1599, 137 1599, 113 -0.0118 0.0464 0.799 0.09751 0.988 0.902 1.08 0.102 0.134 0.447 0.35 1.11 0.851 1.44 0.217 0.132 0.0988 1.005 1.24 0.96 1.61 0.0172 0.137 0.9 0.0456 1.02 0.778 1.33 PRS_PLINK_1e.04 703.1 Ingrowing nail Both 280 4103 13 dermatologic firebrick 4103, 280 1025, 58 1026, 65 1025, 83 1026, 74 0.0712 0.0614 0.247 0.6077 1.07 0.952 1.21 0.117 0.184 0.525 0.2796 1.12 0.784 1.61 0.364 0.175 0.0372 1.43 1.44 1.02 2.03 0.261 0.179 0.143 0.8436 1.3 0.915 1.84 PRS_PLINK_1e.04 704 Diseases of hair and hair follicles Both 1463 15672 13 dermatologic firebrick 15672, 1463 3917, 339 3918, 366 3918, 388 3918, 370 0.0575 0.0276 0.0371 1.431 1.06 1 1.12 0.0808 0.0786 0.304 0.5174 1.08 0.929 1.26 0.132 0.0776 0.0882 1.055 1.14 0.98 1.33 0.0858 0.0785 0.274 0.5617 1.09 0.934 1.27 PRS_PLINK_1e.04 704.1 Alopecia Both 722 7644 13 dermatologic firebrick 7644, 722 1910, 173 1911, 163 1911, 201 1911, 185 0.0636 0.0394 0.106 0.9737 1.07 0.987 1.15 -0.0557 0.113 0.623 0.2056 0.946 0.757 1.18 0.152 0.108 0.162 0.7915 1.16 0.941 1.44 0.0584 0.11 0.596 0.2249 1.06 0.854 1.32 PRS_PLINK_1e.04 704.11 Alopecia Areata Both 40 410 13 dermatologic firebrick 410, 40 103, 11 102, 13 102, 7 103, 9 -0.0318 0.163 0.845 0.07317 0.969 0.704 1.33 -0.0245 0.422 0.954 0.02056 0.976 0.427 2.23 -0.291 0.476 0.541 0.2668 0.748 0.294 1.9 -0.312 0.486 0.52 0.2837 0.732 0.282 1.9 PRS_PLINK_1e.04 704.12 Telogen effluvium Both 36 372 13 dermatologic firebrick 372, 36 93, 9 93, 5 93, 10 93, 12 0.171 0.183 0.351 0.4542 1.19 0.828 1.7 -0.386 0.533 0.469 0.329 0.68 0.239 1.93 0.153 0.469 0.745 0.128 1.16 0.465 2.92 0.201 0.457 0.66 0.1803 1.22 0.5 2.99 PRS_PLINK_1e.04 704.2 Hirsutism Both 143 1954 13 dermatologic firebrick 1954, 143 489, 44 488, 34 488, 29 489, 36 0.0307 0.0857 0.72 0.1424 1.03 0.872 1.22 -0.24 0.232 0.302 0.5206 0.787 0.499 1.24 -0.396 0.242 0.102 0.9915 0.673 0.418 1.08 -0.163 0.23 0.477 0.3212 0.849 0.542 1.33 PRS_PLINK_1e.04 704.8 Other specified diseases of hair and hair follicles Both 749 8810 13 dermatologic firebrick 8810, 749 2203, 172 2202, 196 2202, 186 2203, 195 0.0481 0.0385 0.211 0.6752 1.05 0.973 1.13 0.135 0.108 0.212 0.6729 1.14 0.926 1.42 0.0726 0.109 0.507 0.2948 1.08 0.868 1.33 0.116 0.108 0.283 0.5478 1.12 0.908 1.39 PRS_PLINK_1e.04 705 Disorders of sweat glands Both 317 3624 13 dermatologic firebrick 3624, 317 906, 75 906, 83 906, 89 906, 70 -0.00798 0.0593 0.893 0.04914 0.992 0.883 1.11 0.11 0.165 0.504 0.2977 1.12 0.808 1.54 0.183 0.162 0.259 0.5867 1.2 0.874 1.65 -0.069 0.171 0.686 0.1634 0.933 0.668 1.3 PRS_PLINK_1e.04 705.1 Dyshidrosis Both 81 874 13 dermatologic firebrick 874, 81 219, 23 218, 20 218, 18 219, 20 -0.0801 0.114 0.481 0.3177 0.923 0.739 1.15 -0.0326 0.315 0.918 0.03735 0.968 0.522 1.79 -0.278 0.321 0.385 0.4145 0.757 0.404 1.42 -0.106 0.308 0.73 0.1368 0.899 0.492 1.64 PRS_PLINK_1e.04 705.3 Hidradenitis Both 121 1541 13 dermatologic firebrick 1541, 121 386, 17 385, 38 385, 43 385, 23 0.164 0.0971 0.0906 1.043 1.18 0.974 1.43 0.818 0.293 0.00527 2.278 2.27 1.28 4.03 0.942 0.288 0.00106 2.977 2.57 1.46 4.51 0.321 0.314 0.306 0.5147 1.38 0.746 2.55 PRS_PLINK_1e.04 705.8 Hyperhidrosis Both 425 5731 13 dermatologic firebrick 5731, 425 1433, 108 1433, 100 1432, 110 1433, 107 0.0146 0.0507 0.774 0.1115 1.01 0.919 1.12 -0.0781 0.143 0.584 0.2336 0.925 0.699 1.22 0.014 0.14 0.92 0.03627 1.01 0.772 1.33 -0.00519 0.141 0.971 0.01296 0.995 0.755 1.31 PRS_PLINK_1e.04 706 Diseases of sebaceous glands Both 2824 20189 13 dermatologic firebrick 20189, 2824 5048, 682 5047, 703 5047, 736 5047, 702 0.00273 0.0203 0.893 0.0492 1 0.964 1.04 0.0295 0.0577 0.61 0.215 1.03 0.92 1.15 0.0731 0.0572 0.201 0.6965 1.08 0.962 1.2 0.0339 0.0578 0.558 0.2536 1.03 0.924 1.16 PRS_PLINK_1e.04 706.1 Acne Both 1560 13529 13 dermatologic firebrick 13529, 1560 3383, 371 3382, 387 3382, 412 3382, 389 0.0102 0.0271 0.706 0.151 1.01 0.958 1.07 0.0429 0.077 0.578 0.2384 1.04 0.898 1.21 0.108 0.0759 0.156 0.8058 1.11 0.96 1.29 0.0566 0.0768 0.461 0.3359 1.06 0.91 1.23 PRS_PLINK_1e.04 706.2 Sebaceous cyst Both 1202 12783 13 dermatologic firebrick 12783, 1202 3196, 286 3196, 303 3195, 318 3196, 295 -0.000585 0.0302 0.985 0.006772 0.999 0.942 1.06 0.0555 0.086 0.519 0.2849 1.06 0.893 1.25 0.0978 0.0851 0.251 0.6007 1.1 0.933 1.3 0.0292 0.0865 0.736 0.1331 1.03 0.869 1.22 PRS_PLINK_1e.04 706.3 Seborrhea Both 22 287 13 dermatologic firebrick 287, 22 72, 5 72, 8 71, 4 72, 5 0.0167 0.222 0.94 0.02674 1.02 0.658 1.57 0.352 0.552 0.524 0.2807 1.42 0.482 4.19 -0.136 0.594 0.819 0.08648 0.873 0.272 2.8 0.0193 0.587 0.974 0.01151 1.02 0.322 3.22 PRS_PLINK_1e.04 706.8 Other specified diseases of sebaceous glands Both 509 6108 13 dermatologic firebrick 6108, 509 1527, 115 1527, 137 1527, 126 1527, 131 0.0314 0.0466 0.5 0.3012 1.03 0.942 1.13 0.178 0.131 0.174 0.759 1.19 0.924 1.54 0.0854 0.133 0.52 0.2837 1.09 0.839 1.41 0.125 0.132 0.341 0.4669 1.13 0.876 1.47 PRS_PLINK_1e.04 707 Chronic ulcer of skin Both 719 11646 13 dermatologic firebrick 11646, 719 2912, 201 2911, 174 2911, 165 2912, 179 -0.0895 0.0378 0.018 1.746 0.914 0.849 0.985 -0.141 0.106 0.186 0.731 0.869 0.705 1.07 -0.197 0.108 0.068 1.168 0.821 0.665 1.01 -0.111 0.106 0.292 0.5346 0.895 0.727 1.1 PRS_PLINK_1e.04 707.1 Decubitus ulcer Both 166 3132 13 dermatologic firebrick 3132, 166 783, 41 783, 38 783, 44 783, 43 0.0177 0.079 0.823 0.08465 1.02 0.872 1.19 -0.0415 0.226 0.855 0.06822 0.959 0.616 1.5 0.081 0.219 0.712 0.1476 1.08 0.706 1.67 0.052 0.22 0.813 0.0897 1.05 0.684 1.62 PRS_PLINK_1e.04 707.2 Chronic ulcer of leg or foot Both 154 3817 13 dermatologic firebrick 3817, 154 955, 49 954, 34 954, 36 954, 35 -0.159 0.0809 0.0492 1.308 0.853 0.728 0.999 -0.334 0.222 0.133 0.8759 0.716 0.463 1.11 -0.276 0.221 0.212 0.674 0.759 0.493 1.17 -0.327 0.221 0.139 0.8575 0.721 0.467 1.11 PRS_PLINK_1e.04 707.3 Chronic ulcer of unspecified site Both 484 7175 13 dermatologic firebrick 7175, 484 1794, 135 1794, 120 1793, 114 1794, 115 -0.108 0.0467 0.0211 1.675 0.898 0.82 0.984 -0.125 0.129 0.335 0.4748 0.883 0.685 1.14 -0.176 0.131 0.179 0.747 0.839 0.649 1.08 -0.167 0.131 0.2 0.6997 0.846 0.655 1.09 PRS_PLINK_1e.04 709 Diffuse diseases of connective tissue Both 555 7190 13 dermatologic firebrick 7190, 555 1798, 137 1797, 139 1797, 152 1798, 127 -0.00769 0.0442 0.862 0.06457 0.992 0.91 1.08 0.0106 0.124 0.932 0.03064 1.01 0.792 1.29 0.106 0.122 0.387 0.4126 1.11 0.875 1.41 -0.0791 0.127 0.533 0.2731 0.924 0.72 1.18 PRS_PLINK_1e.04 709.2 Sicca syndrome Both 184 2301 13 dermatologic firebrick 2301, 184 576, 45 575, 40 575, 60 575, 39 -0.0126 0.0752 0.867 0.06223 0.987 0.852 1.14 -0.113 0.222 0.611 0.2142 0.893 0.578 1.38 0.281 0.204 0.168 0.7746 1.32 0.888 1.97 -0.13 0.222 0.559 0.2527 0.878 0.568 1.36 PRS_PLINK_1e.04 709.3 Systemic sclerosis Both 72 1106 13 dermatologic firebrick 1106, 72 277, 21 276, 17 276, 20 277, 14 -0.0843 0.122 0.49 0.3095 0.919 0.723 1.17 -0.232 0.325 0.474 0.3242 0.793 0.42 1.5 -0.011 0.315 0.972 0.01222 0.989 0.533 1.84 -0.394 0.342 0.25 0.6027 0.674 0.345 1.32 PRS_PLINK_1e.04 709.5 Dermatomyositis Both 28 430 13 dermatologic firebrick 430, 28 108, 6 107, 9 107, 8 108, 5 -0.00272 0.195 0.989 0.004853 0.997 0.68 1.46 0.368 0.499 0.46 0.3369 1.45 0.544 3.84 0.315 0.515 0.541 0.2672 1.37 0.499 3.76 -0.0906 0.566 0.873 0.05905 0.913 0.301 2.77 PRS_PLINK_1e.04 709.6 Other specified diffuse diseases of connective tissue Both 44 506 13 dermatologic firebrick 506, 44 127, 14 126, 12 126, 9 127, 9 -0.0659 0.149 0.658 0.1816 0.936 0.699 1.25 -0.089 0.398 0.823 0.08463 0.915 0.42 1.99 -0.464 0.442 0.294 0.5319 0.629 0.264 1.5 -0.485 0.426 0.255 0.594 0.616 0.267 1.42 PRS_PLINK_1e.04 709.7 Unspecified diffuse connective tissue disease Both 354 4744 13 dermatologic firebrick 4744, 354 1186, 83 1186, 92 1186, 94 1186, 85 0.0302 0.0554 0.585 0.2325 1.03 0.925 1.15 0.101 0.156 0.516 0.2877 1.11 0.816 1.5 0.131 0.155 0.396 0.4019 1.14 0.842 1.54 0.0212 0.158 0.893 0.04894 1.02 0.749 1.39 PRS_PLINK_1e.04 710 Osteomyelitis, periostitis, and other infections involving bone Both 355 5514 14 musculoskeletal darkolivegreen 5514, 355 1379, 88 1378, 88 1378, 88 1379, 91 0.0137 0.0544 0.801 0.09658 1.01 0.911 1.13 -0.0174 0.154 0.91 0.04103 0.983 0.727 1.33 0.00218 0.154 0.989 0.004922 1 0.741 1.36 0.0206 0.153 0.893 0.0491 1.02 0.756 1.38 PRS_PLINK_1e.04 710.1 Osteomyelitis Both 329 5256 14 musculoskeletal darkolivegreen 5256, 329 1314, 83 1314, 81 1314, 82 1314, 83 0.00247 0.0564 0.965 0.01547 1 0.898 1.12 -0.0441 0.159 0.782 0.1068 0.957 0.7 1.31 -0.0128 0.159 0.936 0.02887 0.987 0.723 1.35 -0.0181 0.159 0.909 0.04135 0.982 0.719 1.34 PRS_PLINK_1e.04 710.11 Acute osteomyelitis Both 124 2507 14 musculoskeletal darkolivegreen 2507, 124 627, 28 627, 38 626, 30 627, 28 -0.0413 0.0914 0.652 0.186 0.96 0.802 1.15 0.302 0.25 0.227 0.6448 1.35 0.829 2.21 0.0497 0.262 0.849 0.07092 1.05 0.629 1.76 -0.0436 0.267 0.87 0.06039 0.957 0.568 1.61 PRS_PLINK_1e.04 710.12 Chronic osteomyelitis Both 132 2296 14 musculoskeletal darkolivegreen 2296, 132 574, 32 574, 32 574, 29 574, 39 0.0263 0.089 0.768 0.1149 1.03 0.862 1.22 -0.014 0.252 0.956 0.01969 0.986 0.602 1.61 -0.0647 0.258 0.802 0.09577 0.937 0.565 1.55 0.135 0.243 0.58 0.2363 1.14 0.71 1.84 PRS_PLINK_1e.04 710.19 Unspecified osteomyelitis Both 317 5032 14 musculoskeletal darkolivegreen 5032, 317 1258, 80 1258, 80 1258, 79 1258, 78 -0.0124 0.0572 0.828 0.08189 0.988 0.883 1.1 -0.0273 0.162 0.866 0.06263 0.973 0.709 1.34 -0.0156 0.162 0.923 0.03477 0.984 0.717 1.35 -0.0434 0.163 0.79 0.1026 0.958 0.696 1.32 PRS_PLINK_1e.04 711 Arthropathy associated with infections Both 123 1940 14 musculoskeletal darkolivegreen 1940, 123 485, 41 485, 24 485, 31 485, 27 -0.185 0.0947 0.0512 1.291 0.831 0.691 1 -0.527 0.257 0.0404 1.394 0.59 0.357 0.977 -0.267 0.242 0.269 0.5698 0.766 0.477 1.23 -0.424 0.251 0.0917 1.037 0.654 0.4 1.07 PRS_PLINK_1e.04 711.1 Pyogenic arthritis Both 75 1357 14 musculoskeletal darkolivegreen 1357, 75 340, 22 339, 15 339, 21 339, 17 -0.0725 0.119 0.542 0.2656 0.93 0.737 1.17 -0.401 0.33 0.225 0.6484 0.67 0.35 1.28 -0.0405 0.305 0.894 0.04846 0.96 0.528 1.75 -0.263 0.318 0.408 0.3891 0.769 0.413 1.43 PRS_PLINK_1e.04 712 Infective connective tissue disorders Both 45 808 14 musculoskeletal darkolivegreen 808, 45 202, 9 202, 17 202, 7 202, 12 -0.0143 0.153 0.926 0.03353 0.986 0.73 1.33 0.533 0.405 0.188 0.7255 1.7 0.771 3.77 -0.31 0.472 0.511 0.2918 0.733 0.291 1.85 0.24 0.421 0.57 0.2445 1.27 0.556 2.9 PRS_PLINK_1e.04 713 Arthropathy associated with other disorders classified elsewhere Both 75 1404 14 musculoskeletal darkolivegreen 1404, 75 351, 22 351, 20 351, 18 351, 15 -0.118 0.113 0.297 0.5277 0.889 0.712 1.11 -0.128 0.308 0.677 0.1696 0.88 0.481 1.61 -0.218 0.319 0.495 0.3058 0.804 0.431 1.5 -0.455 0.334 0.173 0.7621 0.635 0.33 1.22 PRS_PLINK_1e.04 713.5 Arthropathy associated with neurological disorders Both 18 632 14 musculoskeletal darkolivegreen 632, 18 158, 5 158, 8 158, 4 158, 1 -0.313 0.206 0.129 0.8878 0.731 0.488 1.1 0.664 0.535 0.214 0.6688 1.94 0.681 5.55 0.0255 0.596 0.966 0.0151 1.03 0.319 3.3 -1.1 0.783 0.159 0.7993 0.332 0.0715 1.54 PRS_PLINK_1e.04 714 Rheumatoid arthritis and other inflammatory polyarthropathies Both 743 9042 14 musculoskeletal darkolivegreen 9042, 743 2260, 185 2260, 168 2260, 198 2261, 192 0.0101 0.0383 0.792 0.1013 1.01 0.937 1.09 -0.0982 0.11 0.373 0.4287 0.907 0.731 1.12 0.0647 0.106 0.542 0.266 1.07 0.867 1.31 0.0276 0.107 0.796 0.09912 1.03 0.834 1.27 PRS_PLINK_1e.04 714.1 Rheumatoid arthritis Both 599 7295 14 musculoskeletal darkolivegreen 7295, 599 1823, 146 1824, 139 1823, 168 1824, 146 0.0141 0.0426 0.741 0.13 1.01 0.933 1.1 -0.0514 0.122 0.674 0.171 0.95 0.748 1.21 0.135 0.117 0.248 0.605 1.15 0.91 1.44 -0.00478 0.121 0.969 0.0139 0.995 0.785 1.26 PRS_PLINK_1e.04 714.2 Juvenile rheumatoid arthritis Both 47 510 14 musculoskeletal darkolivegreen 510, 47 128, 15 127, 7 127, 10 128, 15 -0.0898 0.139 0.518 0.286 0.914 0.696 1.2 -0.71 0.45 0.114 0.9416 0.492 0.204 1.19 -0.287 0.416 0.491 0.3093 0.751 0.332 1.7 -0.0261 0.374 0.944 0.02489 0.974 0.468 2.03 PRS_PLINK_1e.04 715 Other inflammatory spondylopathies Both 374 5452 14 musculoskeletal darkolivegreen 5452, 374 1363, 101 1363, 86 1363, 86 1363, 101 -0.0125 0.0529 0.813 0.08981 0.988 0.89 1.1 -0.169 0.151 0.264 0.5783 0.845 0.629 1.14 -0.182 0.151 0.228 0.6417 0.834 0.621 1.12 -0.0121 0.145 0.933 0.02998 0.988 0.743 1.31 PRS_PLINK_1e.04 715.1 Sacroiliitis NEC Both 104 1338 14 musculoskeletal darkolivegreen 1338, 104 335, 28 334, 29 334, 24 335, 23 -0.133 0.0984 0.176 0.7549 0.875 0.722 1.06 0.0542 0.272 0.842 0.07462 1.06 0.62 1.8 -0.167 0.28 0.552 0.258 0.846 0.489 1.47 -0.215 0.286 0.452 0.3445 0.807 0.461 1.41 PRS_PLINK_1e.04 715.2 Ankylosing spondylitis Both 88 1096 14 musculoskeletal darkolivegreen 1096, 88 274, 26 274, 19 274, 18 274, 25 -0.0824 0.107 0.441 0.3555 0.921 0.747 1.14 -0.287 0.301 0.341 0.4676 0.75 0.416 1.35 -0.306 0.31 0.323 0.4908 0.736 0.401 1.35 -0.0326 0.286 0.909 0.04133 0.968 0.552 1.7 PRS_PLINK_1e.04 716 Other arthropathies Both 4792 17674 14 musculoskeletal darkolivegreen 17674, 4792 4418, 1186 4418, 1195 4418, 1222 4419, 1189 -0.00772 0.0168 0.645 0.1901 0.992 0.96 1.03 0.0101 0.0477 0.832 0.07999 1.01 0.92 1.11 0.0289 0.0475 0.543 0.2656 1.03 0.938 1.13 -0.0123 0.0476 0.796 0.09882 0.988 0.9 1.08 PRS_PLINK_1e.04 716.1 Unspecified polyarthropathy or polyarthritis Both 66 972 14 musculoskeletal darkolivegreen 972, 66 243, 18 243, 12 243, 17 243, 19 -0.052 0.124 0.676 0.1699 0.949 0.744 1.21 -0.379 0.365 0.299 0.5238 0.685 0.335 1.4 -0.0656 0.335 0.845 0.07328 0.937 0.486 1.81 0.0388 0.325 0.905 0.04344 1.04 0.55 1.97 PRS_PLINK_1e.04 716.2 Unspecified monoarthritis Both 49 613 14 musculoskeletal darkolivegreen 613, 49 154, 14 153, 17 153, 7 153, 11 -0.0944 0.142 0.507 0.2954 0.91 0.689 1.2 0.2 0.366 0.585 0.2326 1.22 0.596 2.5 -0.649 0.439 0.139 0.8563 0.523 0.221 1.24 -0.208 0.403 0.605 0.2181 0.812 0.369 1.79 PRS_PLINK_1e.04 716.9 Arthropathy NOS Both 4758 17663 14 musculoskeletal darkolivegreen 17663, 4758 4415, 1176 4416, 1187 4415, 1213 4416, 1182 -0.00725 0.0168 0.667 0.1762 0.993 0.961 1.03 0.0123 0.0478 0.798 0.09822 1.01 0.922 1.11 0.0307 0.0476 0.52 0.2843 1.03 0.939 1.13 -0.00924 0.0477 0.846 0.0724 0.991 0.902 1.09 PRS_PLINK_1e.04 717 Polymyalgia Rheumatica Both 58 723 14 musculoskeletal darkolivegreen 723, 58 181, 14 181, 14 180, 9 181, 21 0.146 0.138 0.29 0.5378 1.16 0.883 1.52 -0.132 0.382 0.729 0.1372 0.876 0.414 1.85 -0.434 0.418 0.299 0.5238 0.648 0.285 1.47 0.402 0.35 0.25 0.6015 1.49 0.753 2.97 PRS_PLINK_1e.04 720 Spinal stenosis Both 1119 13086 14 musculoskeletal darkolivegreen 13086, 1119 3272, 283 3271, 268 3271, 292 3272, 276 0.0199 0.0312 0.523 0.2816 1.02 0.96 1.08 -0.0496 0.0886 0.575 0.2403 0.952 0.8 1.13 0.0332 0.087 0.702 0.1535 1.03 0.872 1.23 -0.029 0.0879 0.742 0.1297 0.971 0.818 1.15 PRS_PLINK_1e.04 720.1 Spinal stenosis of lumbar region Both 751 9890 14 musculoskeletal darkolivegreen 9890, 751 2473, 172 2472, 190 2472, 212 2473, 177 0.0372 0.0377 0.323 0.4904 1.04 0.964 1.12 0.109 0.109 0.315 0.5019 1.12 0.902 1.38 0.213 0.106 0.0451 1.345 1.24 1 1.52 0.0337 0.11 0.76 0.1192 1.03 0.833 1.28 PRS_PLINK_1e.04 721 Spondylosis and allied disorders Both 1749 16034 14 musculoskeletal darkolivegreen 16034, 1749 4009, 435 4008, 416 4008, 450 4009, 447 0.0108 0.0252 0.668 0.1751 1.01 0.962 1.06 -0.0363 0.0723 0.615 0.2109 0.964 0.837 1.11 0.028 0.071 0.693 0.159 1.03 0.895 1.18 0.0316 0.0711 0.657 0.1827 1.03 0.898 1.19 PRS_PLINK_1e.04 721.1 Spondylosis without myelopathy Both 1621 15621 14 musculoskeletal darkolivegreen 15621, 1621 3906, 401 3905, 386 3905, 419 3905, 414 0.0107 0.0261 0.683 0.1658 1.01 0.96 1.06 -0.0315 0.075 0.675 0.1707 0.969 0.837 1.12 0.0392 0.0736 0.595 0.2258 1.04 0.9 1.2 0.0347 0.0737 0.638 0.1954 1.04 0.896 1.2 PRS_PLINK_1e.04 721.2 Spondylosis with myelopathy Both 260 3648 14 musculoskeletal darkolivegreen 3648, 260 912, 65 912, 68 912, 66 912, 60 -0.0299 0.0634 0.637 0.1961 0.971 0.857 1.1 0.0532 0.178 0.764 0.1168 1.05 0.745 1.49 0.0459 0.179 0.797 0.0983 1.05 0.737 1.49 -0.0813 0.183 0.658 0.1819 0.922 0.644 1.32 PRS_PLINK_1e.04 721.8 Other allied disorders of spine Both 85 1127 14 musculoskeletal darkolivegreen 1127, 85 282, 17 282, 27 281, 21 282, 19 -0.0342 0.112 0.761 0.1186 0.966 0.775 1.2 0.425 0.312 0.172 0.7635 1.53 0.831 2.82 0.164 0.324 0.613 0.2123 1.18 0.624 2.22 0.125 0.332 0.708 0.1503 1.13 0.591 2.17 PRS_PLINK_1e.04 722 Intervertebral disc disorders Both 2318 17733 14 musculoskeletal darkolivegreen 17733, 2318 4434, 569 4433, 599 4433, 569 4433, 580 0.00501 0.0222 0.821 0.08567 1.01 0.962 1.05 0.0549 0.0624 0.379 0.421 1.06 0.935 1.19 -0.00476 0.0632 0.94 0.02691 0.995 0.879 1.13 0.0169 0.0628 0.789 0.1031 1.02 0.899 1.15 PRS_PLINK_1e.04 722.1 Displacement of intervertebral disc Both 1414 15837 14 musculoskeletal darkolivegreen 15837, 1414 3960, 347 3959, 375 3959, 356 3959, 336 -0.0122 0.0277 0.66 0.1807 0.988 0.936 1.04 0.0788 0.0777 0.311 0.5075 1.08 0.929 1.26 0.0242 0.0786 0.758 0.1201 1.02 0.878 1.2 -0.0298 0.0796 0.708 0.15 0.971 0.83 1.13 PRS_PLINK_1e.04 722.3 Schmorl's nodes Both 41 624 14 musculoskeletal darkolivegreen 624, 41 156, 11 156, 10 156, 10 156, 9 -0.221 0.151 0.143 0.8445 0.802 0.597 1.08 -0.0792 0.43 0.854 0.06857 0.924 0.397 2.15 0.0153 0.434 0.972 0.01241 1.02 0.433 2.38 -0.137 0.431 0.751 0.1242 0.872 0.375 2.03 PRS_PLINK_1e.04 722.6 Degeneration of intervertebral disc Both 1338 14764 14 musculoskeletal darkolivegreen 14764, 1338 3691, 314 3691, 343 3691, 337 3691, 344 0.048 0.0287 0.0947 1.024 1.05 0.992 1.11 0.0961 0.0814 0.238 0.6233 1.1 0.938 1.29 0.0748 0.0818 0.361 0.443 1.08 0.918 1.26 0.0974 0.0813 0.231 0.6362 1.1 0.94 1.29 PRS_PLINK_1e.04 722.7 Intervertebral disc disorder with myelopathy Both 163 2289 14 musculoskeletal darkolivegreen 2289, 163 573, 35 572, 44 572, 43 572, 41 0.0357 0.0808 0.658 0.1815 1.04 0.885 1.21 0.195 0.23 0.397 0.401 1.21 0.774 1.91 0.205 0.231 0.375 0.4258 1.23 0.78 1.93 0.112 0.234 0.634 0.198 1.12 0.707 1.77 PRS_PLINK_1e.04 722.8 Postlaminectomy syndrome Both 127 1804 14 musculoskeletal darkolivegreen 1804, 127 451, 23 451, 38 451, 35 451, 31 0.0192 0.0926 0.836 0.07774 1.02 0.85 1.22 0.546 0.266 0.0404 1.393 1.73 1.02 2.91 0.426 0.27 0.114 0.9429 1.53 0.903 2.6 0.28 0.275 0.309 0.5107 1.32 0.772 2.27 PRS_PLINK_1e.04 722.9 Other and unspecified disc disorder Both 752 9284 14 musculoskeletal darkolivegreen 9284, 752 2321, 168 2321, 204 2321, 192 2321, 187 0.0219 0.0376 0.56 0.2522 1.02 0.95 1.1 0.203 0.108 0.0599 1.222 1.22 0.992 1.51 0.148 0.109 0.174 0.7592 1.16 0.936 1.44 0.115 0.11 0.297 0.5267 1.12 0.904 1.39 PRS_PLINK_1e.04 723 Other disorders of cervical region Both 390 4730 14 musculoskeletal darkolivegreen 4730, 390 1183, 95 1182, 97 1182, 84 1183, 114 0.0672 0.0531 0.205 0.6872 1.07 0.964 1.19 0.0245 0.149 0.869 0.06101 1.02 0.766 1.37 -0.118 0.154 0.444 0.3526 0.889 0.658 1.2 0.185 0.144 0.198 0.7043 1.2 0.908 1.6 PRS_PLINK_1e.04 723.1 Torticollis Both 110 1265 14 musculoskeletal darkolivegreen 1265, 110 317, 26 316, 26 316, 26 316, 32 0.0888 0.0946 0.348 0.4585 1.09 0.908 1.32 0.0173 0.281 0.951 0.02189 1.02 0.586 1.77 0.0188 0.281 0.947 0.02383 1.02 0.588 1.77 0.217 0.267 0.416 0.3807 1.24 0.736 2.1 PRS_PLINK_1e.04 724 Other and unspecified disorders of back Both 1639 16632 14 musculoskeletal darkolivegreen 16632, 1639 4158, 391 4158, 418 4158, 434 4158, 395 0.0058 0.026 0.824 0.08431 1.01 0.956 1.06 0.0626 0.0737 0.396 0.4025 1.06 0.921 1.23 0.102 0.0732 0.161 0.7922 1.11 0.96 1.28 0.00428 0.0747 0.954 0.02034 1 0.868 1.16 PRS_PLINK_1e.04 724.1 Disorders of sacrum Both 914 11200 14 musculoskeletal darkolivegreen 11200, 914 2800, 209 2800, 247 2800, 234 2800, 223 0.00566 0.0347 0.871 0.06022 1.01 0.94 1.08 0.167 0.0975 0.0859 1.066 1.18 0.977 1.43 0.108 0.0986 0.272 0.566 1.11 0.919 1.35 0.0632 0.0997 0.526 0.279 1.07 0.876 1.3 PRS_PLINK_1e.04 724.2 Disorders of coccyx Both 190 2255 14 musculoskeletal darkolivegreen 2255, 190 564, 45 564, 38 563, 57 564, 50 0.027 0.0747 0.718 0.1438 1.03 0.887 1.19 -0.186 0.225 0.408 0.3892 0.83 0.534 1.29 0.226 0.207 0.276 0.5598 1.25 0.835 1.88 0.102 0.211 0.628 0.2018 1.11 0.732 1.68 PRS_PLINK_1e.04 724.8 Other symptoms referable to back Both 359 4723 14 musculoskeletal darkolivegreen 4723, 359 1181, 92 1181, 86 1180, 97 1181, 84 -0.0552 0.0548 0.313 0.5043 0.946 0.85 1.05 -0.095 0.155 0.539 0.2683 0.909 0.672 1.23 0.0547 0.15 0.715 0.1454 1.06 0.787 1.42 -0.0792 0.155 0.61 0.2148 0.924 0.682 1.25 PRS_PLINK_1e.04 724.9 Other unspecified back disorders Both 511 6570 14 musculoskeletal darkolivegreen 6570, 511 1643, 124 1642, 127 1642, 131 1643, 129 0.0424 0.0464 0.361 0.4431 1.04 0.953 1.14 0.0119 0.13 0.927 0.03272 1.01 0.784 1.31 0.0652 0.13 0.615 0.2115 1.07 0.828 1.38 0.0365 0.13 0.778 0.1088 1.04 0.804 1.34 PRS_PLINK_1e.04 726 Peripheral enthesopathies and allied syndromes Both 4325 16180 14 musculoskeletal darkolivegreen 16180, 4325 4045, 1122 4045, 1022 4045, 1109 4045, 1071 -0.0104 0.0172 0.545 0.2633 0.99 0.957 1.02 -0.0896 0.049 0.0673 1.172 0.914 0.831 1.01 -0.00435 0.0482 0.928 0.03242 0.996 0.906 1.09 -0.0443 0.0485 0.361 0.4421 0.957 0.87 1.05 PRS_PLINK_1e.04 726.1 Enthesopathy Both 3300 16121 14 musculoskeletal darkolivegreen 16121, 3300 4031, 854 4030, 782 4030, 839 4030, 825 -0.00382 0.0192 0.842 0.07449 0.996 0.959 1.03 -0.085 0.0546 0.119 0.9229 0.919 0.825 1.02 -0.0106 0.0538 0.843 0.07413 0.989 0.89 1.1 -0.0333 0.054 0.537 0.2702 0.967 0.87 1.08 PRS_PLINK_1e.04 726.2 Synoviopathy Both 407 4653 14 musculoskeletal darkolivegreen 4653, 407 1164, 100 1163, 93 1163, 107 1163, 107 0.0456 0.051 0.372 0.4299 1.05 0.947 1.16 -0.0581 0.149 0.697 0.1565 0.944 0.704 1.26 0.0793 0.145 0.583 0.2341 1.08 0.815 1.44 0.0824 0.145 0.568 0.2454 1.09 0.818 1.44 PRS_PLINK_1e.04 726.3 Bursitis Both 689 8062 14 musculoskeletal darkolivegreen 8062, 689 2016, 190 2015, 159 2015, 193 2016, 147 -0.066 0.0393 0.0927 1.033 0.936 0.867 1.01 -0.172 0.112 0.124 0.9049 0.842 0.677 1.05 0.0217 0.107 0.839 0.07621 1.02 0.829 1.26 -0.244 0.114 0.0322 1.492 0.783 0.626 0.979 PRS_PLINK_1e.04 726.4 Calcaneal spur; Exostosis NOS Both 468 5641 14 musculoskeletal darkolivegreen 5641, 468 1411, 122 1410, 114 1410, 121 1410, 110 -0.056 0.0471 0.234 0.6303 0.946 0.862 1.04 -0.0487 0.135 0.718 0.1437 0.952 0.731 1.24 0.00456 0.134 0.973 0.01199 1 0.773 1.31 -0.0902 0.136 0.508 0.2941 0.914 0.7 1.19 PRS_PLINK_1e.04 727 Other disorders of synovium, tendon, and bursa Both 3139 16123 14 musculoskeletal darkolivegreen 16123, 3139 4031, 817 4031, 732 4030, 793 4031, 797 0.00232 0.0196 0.906 0.04299 1 0.965 1.04 -0.111 0.0559 0.0478 1.32 0.895 0.802 0.999 -0.0289 0.055 0.599 0.2223 0.972 0.872 1.08 -0.0263 0.0549 0.631 0.1999 0.974 0.875 1.08 PRS_PLINK_1e.04 727.1 Synovitis and tenosynovitis Both 1281 13070 14 musculoskeletal darkolivegreen 13070, 1281 3268, 342 3267, 304 3267, 310 3268, 325 -0.0135 0.0291 0.643 0.1918 0.987 0.932 1.04 -0.116 0.0826 0.16 0.7958 0.89 0.757 1.05 -0.0969 0.0822 0.238 0.6229 0.908 0.773 1.07 -0.0507 0.0813 0.533 0.2734 0.951 0.811 1.11 PRS_PLINK_1e.04 727.2 Bursitis disorders Both 131 1784 14 musculoskeletal darkolivegreen 1784, 131 446, 39 446, 30 446, 28 446, 34 -0.0239 0.0887 0.788 0.1035 0.976 0.821 1.16 -0.236 0.246 0.338 0.4714 0.79 0.487 1.28 -0.294 0.252 0.243 0.614 0.746 0.455 1.22 -0.119 0.239 0.62 0.2079 0.888 0.556 1.42 PRS_PLINK_1e.04 727.4 Ganglion and cyst of synovium, tendon, and bursa Both 614 6826 14 musculoskeletal darkolivegreen 6826, 614 1707, 150 1706, 131 1706, 166 1707, 167 0.0243 0.0419 0.562 0.2502 1.02 0.944 1.11 -0.118 0.124 0.339 0.4699 0.888 0.697 1.13 0.101 0.117 0.389 0.4106 1.11 0.879 1.39 0.105 0.117 0.371 0.4304 1.11 0.883 1.4 PRS_PLINK_1e.04 727.5 Rupture of synovium Both 175 2126 14 musculoskeletal darkolivegreen 2126, 175 532, 44 531, 47 531, 41 532, 43 -0.0256 0.0781 0.743 0.1288 0.975 0.836 1.14 0.0913 0.216 0.672 0.1723 1.1 0.718 1.67 -0.0728 0.222 0.743 0.1288 0.93 0.601 1.44 -0.0231 0.22 0.916 0.03798 0.977 0.635 1.5 PRS_PLINK_1e.04 727.6 Rupture of tendon, nontraumatic Both 861 9674 14 musculoskeletal darkolivegreen 9674, 861 2419, 236 2418, 199 2418, 219 2419, 207 -0.0203 0.0351 0.563 0.2496 0.98 0.915 1.05 -0.17 0.1 0.0905 1.043 0.844 0.694 1.03 -0.0659 0.0981 0.502 0.2997 0.936 0.772 1.13 -0.128 0.0992 0.198 0.703 0.88 0.725 1.07 PRS_PLINK_1e.04 727.7 Contracture of tendon (sheath) Both 294 3346 14 musculoskeletal darkolivegreen 3346, 294 837, 73 836, 76 836, 74 837, 71 -0.00455 0.0606 0.94 0.02679 0.995 0.884 1.12 0.044 0.17 0.796 0.09919 1.04 0.749 1.46 0.0191 0.172 0.912 0.04018 1.02 0.728 1.43 -0.0111 0.172 0.949 0.0228 0.989 0.705 1.39 PRS_PLINK_1e.04 727.8 Plica syndrome Both 111 925 14 musculoskeletal darkolivegreen 925, 111 232, 27 231, 26 231, 34 231, 24 -0.00393 0.097 0.968 0.01426 0.996 0.824 1.2 0.0242 0.29 0.933 0.02992 1.02 0.58 1.81 0.259 0.272 0.34 0.4681 1.3 0.761 2.21 -0.111 0.288 0.701 0.1543 0.895 0.509 1.58 PRS_PLINK_1e.04 728 Disorders of muscle, ligament, and fascia Both 1648 15555 14 musculoskeletal darkolivegreen 15555, 1648 3889, 416 3889, 391 3888, 421 3889, 420 0.00963 0.0259 0.71 0.149 1.01 0.96 1.06 -0.0573 0.074 0.439 0.3574 0.944 0.817 1.09 0.00778 0.0729 0.915 0.0386 1.01 0.874 1.16 0.0069 0.0729 0.925 0.03408 1.01 0.873 1.16 PRS_PLINK_1e.04 728.1 Muscular calcification and ossification Both 32 418 14 musculoskeletal darkolivegreen 418, 32 105, 9 104, 8 104, 7 105, 8 -0.0952 0.177 0.59 0.2289 0.909 0.643 1.29 -0.102 0.484 0.833 0.07924 0.903 0.35 2.33 -0.337 0.496 0.497 0.304 0.714 0.27 1.89 -0.246 0.481 0.61 0.2147 0.782 0.305 2.01 PRS_PLINK_1e.04 728.2 Laxity of ligament or hypermobility syndrome Both 126 1526 14 musculoskeletal darkolivegreen 1526, 126 382, 24 381, 28 381, 39 382, 35 0.108 0.094 0.249 0.6045 1.11 0.927 1.34 0.126 0.282 0.655 0.1837 1.13 0.652 1.97 0.438 0.265 0.0986 1.006 1.55 0.922 2.61 0.402 0.27 0.136 0.8662 1.5 0.881 2.54 PRS_PLINK_1e.04 728.7 Fasciitis Both 1135 11587 14 musculoskeletal darkolivegreen 11587, 1135 2897, 294 2897, 282 2896, 290 2897, 269 -0.0547 0.031 0.0777 1.11 0.947 0.891 1.01 -0.0425 0.0875 0.627 0.2027 0.958 0.807 1.14 -0.0209 0.0869 0.81 0.09166 0.979 0.826 1.16 -0.0951 0.0884 0.282 0.5499 0.909 0.765 1.08 PRS_PLINK_1e.04 728.71 Contracture of palmar fascia [Dupuytren's disease] Both 138 1555 14 musculoskeletal darkolivegreen 1555, 138 389, 37 389, 38 388, 28 389, 35 -0.13 0.0848 0.126 0.8981 0.878 0.744 1.04 0.025 0.238 0.916 0.03788 1.03 0.643 1.63 -0.229 0.256 0.371 0.4305 0.795 0.481 1.31 -0.0836 0.242 0.73 0.1368 0.92 0.572 1.48 PRS_PLINK_1e.04 729 Other disorders of soft tissues Both 1166 13805 14 musculoskeletal darkolivegreen 13805, 1166 3452, 294 3451, 274 3451, 310 3451, 287 0.00764 0.0305 0.802 0.09588 1.01 0.949 1.07 -0.0606 0.0873 0.488 0.3118 0.941 0.793 1.12 0.0579 0.0849 0.495 0.3052 1.06 0.897 1.25 -0.021 0.0863 0.807 0.09294 0.979 0.827 1.16 PRS_PLINK_1e.04 729.1 Rheumatism, unspecified and fibrositis Both 19 327 14 musculoskeletal darkolivegreen 327, 19 82, 6 82, 4 81, 3 82, 6 -0.0235 0.21 0.911 0.04057 0.977 0.647 1.47 -0.262 0.61 0.668 0.1752 0.77 0.233 2.54 -0.629 0.638 0.325 0.4888 0.533 0.153 1.86 -0.00808 0.535 0.988 0.005266 0.992 0.347 2.83 PRS_PLINK_1e.04 729.3 Panniculitis Both 33 596 14 musculoskeletal darkolivegreen 596, 33 149, 6 149, 10 149, 9 149, 8 0.0673 0.174 0.699 0.1556 1.07 0.76 1.5 0.333 0.482 0.49 0.3098 1.39 0.542 3.59 0.437 0.488 0.371 0.431 1.55 0.595 4.03 0.298 0.506 0.556 0.2549 1.35 0.5 3.63 PRS_PLINK_1e.04 729.7 Nontraumatic compartment syndrome Both 19 339 14 musculoskeletal darkolivegreen 339, 19 85, 7 85, 3 84, 4 85, 5 -0.595 0.234 0.0111 1.955 0.551 0.348 0.873 -0.66 0.625 0.291 0.5359 0.517 0.152 1.76 -0.585 0.595 0.325 0.4876 0.557 0.174 1.79 -0.281 0.538 0.602 0.2203 0.755 0.263 2.17 PRS_PLINK_1e.04 731 Osteitis deformans and osteopathies associated with other disorders classified elsewhere Both 28 765 14 musculoskeletal darkolivegreen 765, 28 192, 4 191, 9 191, 10 191, 5 0.0228 0.179 0.899 0.04638 1.02 0.72 1.45 0.773 0.529 0.144 0.8409 2.17 0.767 6.12 0.927 0.537 0.0842 1.075 2.53 0.882 7.24 0.291 0.574 0.612 0.213 1.34 0.434 4.12 PRS_PLINK_1e.04 732 Osteochondropathies Both 225 2367 14 musculoskeletal darkolivegreen 2367, 225 592, 73 592, 53 591, 47 592, 52 -0.158 0.0697 0.0233 1.632 0.854 0.745 0.979 -0.31 0.189 0.101 0.9976 0.734 0.507 1.06 -0.44 0.195 0.0241 1.619 0.644 0.44 0.944 -0.311 0.189 0.1 0.9998 0.733 0.506 1.06 PRS_PLINK_1e.04 732.1 Juvenile osteochondrosis Both 111 1182 14 musculoskeletal darkolivegreen 1182, 111 296, 40 295, 24 295, 24 296, 23 -0.211 0.0987 0.0322 1.492 0.809 0.667 0.982 -0.459 0.269 0.0886 1.053 0.632 0.373 1.07 -0.518 0.269 0.0546 1.263 0.596 0.352 1.01 -0.483 0.27 0.0737 1.133 0.617 0.364 1.05 PRS_PLINK_1e.04 732.7 Osteochondritis dissecans Both 65 621 14 musculoskeletal darkolivegreen 621, 65 156, 24 155, 12 155, 12 155, 17 -0.206 0.125 0.098 1.009 0.813 0.637 1.04 -0.671 0.364 0.0653 1.185 0.511 0.25 1.04 -0.698 0.36 0.0528 1.278 0.498 0.246 1.01 -0.303 0.336 0.368 0.4345 0.739 0.382 1.43 PRS_PLINK_1e.04 733 Other disorders of bone and cartilage Both 1730 13356 14 musculoskeletal darkolivegreen 13356, 1730 3338, 420 3339, 459 3339, 428 3339, 423 0.00228 0.026 0.93 0.03142 1 0.952 1.05 0.0883 0.0727 0.225 0.6484 1.09 0.947 1.26 0.00832 0.0738 0.91 0.04087 1.01 0.873 1.17 -0.00105 0.074 0.989 0.004946 0.999 0.864 1.15 PRS_PLINK_1e.04 733.2 Cyst of bone Both 91 1007 14 musculoskeletal darkolivegreen 1007, 91 252, 22 252, 22 251, 27 252, 20 -0.0272 0.108 0.801 0.09663 0.973 0.788 1.2 -0.038 0.304 0.901 0.04545 0.963 0.53 1.75 0.209 0.293 0.477 0.3214 1.23 0.693 2.19 -0.112 0.309 0.717 0.1444 0.894 0.488 1.64 PRS_PLINK_1e.04 733.4 Aseptic necrosis of bone Both 195 2396 14 musculoskeletal darkolivegreen 2396, 195 599, 55 599, 44 599, 52 599, 44 -0.00492 0.073 0.946 0.024 0.995 0.862 1.15 -0.216 0.207 0.297 0.5267 0.806 0.537 1.21 -0.0448 0.199 0.822 0.08491 0.956 0.647 1.41 -0.206 0.207 0.32 0.4948 0.814 0.542 1.22 PRS_PLINK_1e.04 733.6 Costochondritis Both 175 2042 14 musculoskeletal darkolivegreen 2042, 175 511, 43 510, 45 510, 44 511, 43 -0.0233 0.0768 0.761 0.1184 0.977 0.84 1.14 0.0971 0.221 0.66 0.1804 1.1 0.715 1.7 0.034 0.22 0.877 0.05699 1.03 0.672 1.59 0.0271 0.221 0.902 0.04458 1.03 0.667 1.58 PRS_PLINK_1e.04 733.8 Malunion and nonunion of fracture Both 392 4355 14 musculoskeletal darkolivegreen 4355, 392 1089, 90 1089, 100 1088, 104 1089, 98 0.0294 0.0527 0.577 0.2389 1.03 0.929 1.14 0.0848 0.151 0.574 0.2412 1.09 0.81 1.46 0.146 0.149 0.329 0.4834 1.16 0.864 1.55 0.104 0.152 0.492 0.3081 1.11 0.825 1.49 PRS_PLINK_1e.04 733.9 Chondromalacia Both 68 660 14 musculoskeletal darkolivegreen 660, 68 165, 25 165, 11 165, 16 165, 16 -0.164 0.125 0.19 0.721 0.849 0.664 1.08 -0.778 0.368 0.0345 1.462 0.459 0.223 0.945 -0.487 0.337 0.149 0.8264 0.615 0.317 1.19 -0.542 0.337 0.108 0.9671 0.582 0.301 1.13 PRS_PLINK_1e.04 735 Acquired foot deformities Both 1273 14033 14 musculoskeletal darkolivegreen 14033, 1273 3509, 318 3508, 314 3508, 322 3508, 319 -0.0145 0.0293 0.62 0.2074 0.986 0.931 1.04 -0.0113 0.083 0.892 0.04975 0.989 0.84 1.16 0.0086 0.0826 0.917 0.03758 1.01 0.858 1.19 0.00665 0.0827 0.936 0.02876 1.01 0.856 1.18 PRS_PLINK_1e.04 735.1 Flat foot Both 242 2802 14 musculoskeletal darkolivegreen 2802, 242 701, 48 700, 56 700, 82 701, 56 0.0542 0.068 0.426 0.371 1.06 0.924 1.21 0.158 0.203 0.436 0.3606 1.17 0.787 1.74 0.501 0.188 0.00771 2.113 1.65 1.14 2.39 0.173 0.201 0.391 0.4079 1.19 0.801 1.76 PRS_PLINK_1e.04 735.2 Acquired toe deformities Both 389 4817 14 musculoskeletal darkolivegreen 4817, 389 1205, 95 1204, 107 1204, 94 1204, 93 -0.0308 0.0519 0.553 0.2575 0.97 0.876 1.07 0.137 0.146 0.346 0.4604 1.15 0.862 1.53 -0.0111 0.15 0.941 0.02638 0.989 0.737 1.33 -0.0162 0.151 0.914 0.03901 0.984 0.733 1.32 PRS_PLINK_1e.04 735.21 Hammer toe (acquired) Both 194 2757 14 musculoskeletal darkolivegreen 2757, 194 690, 50 689, 53 689, 50 689, 41 -0.076 0.0723 0.293 0.5325 0.927 0.804 1.07 0.0588 0.202 0.771 0.1132 1.06 0.714 1.57 -0.00858 0.205 0.967 0.01475 0.991 0.664 1.48 -0.211 0.214 0.324 0.4893 0.81 0.532 1.23 PRS_PLINK_1e.04 735.23 Hallux rigidus Both 164 1659 14 musculoskeletal darkolivegreen 1659, 164 415, 38 415, 47 414, 39 415, 40 0.0169 0.0791 0.831 0.08056 1.02 0.871 1.19 0.2 0.225 0.374 0.4269 1.22 0.785 1.9 -0.00747 0.235 0.975 0.01117 0.993 0.627 1.57 0.00444 0.235 0.985 0.00659 1 0.633 1.59 PRS_PLINK_1e.04 735.3 Hallux valgus (Bunion) Both 614 6723 14 musculoskeletal darkolivegreen 6723, 614 1681, 160 1681, 156 1680, 147 1681, 151 -0.0519 0.0419 0.215 0.6678 0.949 0.875 1.03 -0.0235 0.117 0.841 0.07502 0.977 0.776 1.23 -0.0724 0.119 0.542 0.2657 0.93 0.737 1.17 -0.0471 0.118 0.69 0.1611 0.954 0.757 1.2 PRS_PLINK_1e.04 736 Other acquired deformities of limbs Both 1176 12795 14 musculoskeletal darkolivegreen 12795, 1176 3199, 297 3199, 273 3198, 315 3199, 291 -0.00954 0.0304 0.754 0.1228 0.991 0.933 1.05 -0.0792 0.0873 0.364 0.4387 0.924 0.779 1.1 0.064 0.0846 0.449 0.3476 1.07 0.903 1.26 -0.0123 0.0861 0.887 0.05219 0.988 0.834 1.17 PRS_PLINK_1e.04 736.1 Acquired deformities of forearm Both 39 498 14 musculoskeletal darkolivegreen 498, 39 125, 8 124, 11 124, 11 125, 9 0.0359 0.158 0.82 0.08606 1.04 0.761 1.41 0.374 0.453 0.41 0.3877 1.45 0.598 3.53 0.362 0.449 0.42 0.3767 1.44 0.596 3.46 0.242 0.478 0.613 0.2123 1.27 0.499 3.25 PRS_PLINK_1e.04 736.2 Acquired deformities of finger Both 97 1109 14 musculoskeletal darkolivegreen 1109, 97 278, 26 277, 24 277, 27 277, 20 -0.133 0.104 0.198 0.7024 0.875 0.714 1.07 -0.0792 0.288 0.783 0.1061 0.924 0.525 1.62 -0.000286 0.284 0.999 0.0003484 1 0.573 1.74 -0.297 0.3 0.323 0.4913 0.743 0.412 1.34 PRS_PLINK_1e.04 736.3 Acquired deformities of hip Both 42 399 14 musculoskeletal darkolivegreen 399, 42 100, 12 100, 8 99, 9 100, 13 -0.0388 0.16 0.809 0.09226 0.962 0.703 1.32 -0.441 0.449 0.326 0.4871 0.644 0.267 1.55 -0.253 0.449 0.573 0.242 0.776 0.322 1.87 0.0459 0.412 0.911 0.04033 1.05 0.467 2.35 PRS_PLINK_1e.04 736.4 Genu valgum or varum (acquired) Both 139 1366 14 musculoskeletal darkolivegreen 1366, 139 342, 34 341, 34 341, 42 342, 29 -0.0298 0.0898 0.74 0.1305 0.971 0.814 1.16 0.00283 0.249 0.991 0.003956 1 0.615 1.63 0.245 0.24 0.307 0.5126 1.28 0.798 2.05 -0.133 0.26 0.609 0.2155 0.876 0.526 1.46 PRS_PLINK_1e.04 736.5 Acquired deformities of knee Both 100 1060 14 musculoskeletal darkolivegreen 1060, 100 265, 25 265, 24 265, 33 265, 18 -0.0803 0.104 0.441 0.3551 0.923 0.752 1.13 -0.0539 0.291 0.853 0.06897 0.948 0.536 1.68 0.28 0.274 0.306 0.5144 1.32 0.774 2.26 -0.307 0.311 0.323 0.4906 0.735 0.4 1.35 PRS_PLINK_1e.04 736.6 Unequal leg length (acquired) Both 146 1636 14 musculoskeletal darkolivegreen 1636, 146 409, 50 409, 21 409, 37 409, 38 -0.0274 0.0854 0.748 0.126 0.973 0.823 1.15 -0.827 0.265 0.00181 2.742 0.437 0.26 0.735 -0.301 0.224 0.179 0.7465 0.74 0.477 1.15 -0.255 0.225 0.258 0.5881 0.775 0.499 1.21 PRS_PLINK_1e.04 737 Curvature of spine Both 663 7538 14 musculoskeletal darkolivegreen 7538, 663 1885, 164 1884, 171 1884, 164 1885, 164 0.00652 0.0409 0.873 0.05887 1.01 0.929 1.09 0.0435 0.114 0.702 0.1537 1.04 0.836 1.3 -0.00412 0.115 0.971 0.01263 0.996 0.795 1.25 -4.2e-05 0.115 1 0.000127 1 0.799 1.25 PRS_PLINK_1e.04 737.1 Kyphosis (acquired) Both 165 2097 14 musculoskeletal darkolivegreen 2097, 165 525, 43 524, 49 524, 36 524, 37 -0.119 0.0792 0.133 0.8758 0.888 0.76 1.04 0.126 0.214 0.557 0.2538 1.13 0.745 1.73 -0.167 0.23 0.467 0.331 0.846 0.54 1.33 -0.138 0.228 0.545 0.2637 0.871 0.557 1.36 PRS_PLINK_1e.04 737.2 Lordosis (acquired) Both 22 310 14 musculoskeletal darkolivegreen 310, 22 78, 3 77, 7 77, 7 78, 5 0.128 0.212 0.547 0.2624 1.14 0.75 1.72 0.879 0.652 0.178 0.7501 2.41 0.671 8.65 0.946 0.696 0.174 0.7603 2.58 0.659 10.1 0.224 0.674 0.739 0.1312 1.25 0.334 4.68 PRS_PLINK_1e.04 737.3 Kyphoscoliosis and scoliosis Both 528 5855 14 musculoskeletal darkolivegreen 5855, 528 1464, 127 1464, 135 1463, 128 1464, 138 0.042 0.0459 0.36 0.4431 1.04 0.953 1.14 0.0619 0.128 0.63 0.2006 1.06 0.827 1.37 0.00333 0.13 0.98 0.008982 1 0.778 1.29 0.0815 0.128 0.524 0.2809 1.08 0.845 1.39 PRS_PLINK_1e.04 738 Other acquired musculoskeletal deformity Both 1060 11505 14 musculoskeletal darkolivegreen 11505, 1060 2877, 240 2876, 282 2876, 261 2876, 277 0.0428 0.0323 0.185 0.7336 1.04 0.98 1.11 0.161 0.0914 0.0781 1.107 1.17 0.982 1.41 0.0903 0.0931 0.332 0.4787 1.09 0.912 1.31 0.147 0.0918 0.11 0.9572 1.16 0.967 1.39 PRS_PLINK_1e.04 738.4 Acquired spondylolisthesis Both 326 4218 14 musculoskeletal darkolivegreen 4218, 326 1055, 70 1054, 88 1054, 83 1055, 85 0.0673 0.0576 0.242 0.6157 1.07 0.956 1.2 0.254 0.165 0.123 0.9085 1.29 0.933 1.78 0.198 0.167 0.235 0.6298 1.22 0.879 1.69 0.202 0.166 0.223 0.6517 1.22 0.884 1.69 PRS_PLINK_1e.04 739 Contracture of joint Both 269 3059 14 musculoskeletal darkolivegreen 3059, 269 765, 75 765, 71 764, 73 765, 50 -0.162 0.0632 0.0105 1.977 0.851 0.752 0.963 -0.0686 0.172 0.69 0.1611 0.934 0.666 1.31 -0.0309 0.171 0.857 0.06722 0.97 0.694 1.36 -0.41 0.188 0.0289 1.539 0.664 0.459 0.959 PRS_PLINK_1e.04 740 Osteoarthrosis Both 5715 17429 14 musculoskeletal darkolivegreen 17429, 5715 4357, 1421 4357, 1434 4357, 1459 4357, 1401 -0.0101 0.0159 0.524 0.2804 0.99 0.96 1.02 0.0091 0.0451 0.84 0.07578 1.01 0.924 1.1 0.0182 0.045 0.686 0.164 1.02 0.932 1.11 -0.0331 0.0452 0.463 0.3341 0.967 0.885 1.06 PRS_PLINK_1e.04 740.1 Osteoarthritis; localized Both 2402 14859 14 musculoskeletal darkolivegreen 14859, 2402 3714, 603 3715, 602 3714, 627 3715, 570 -0.0248 0.0222 0.265 0.5774 0.976 0.934 1.02 0.00449 0.0632 0.943 0.02532 1 0.888 1.14 0.0358 0.0628 0.569 0.2451 1.04 0.916 1.17 -0.0688 0.0639 0.281 0.5509 0.933 0.824 1.06 PRS_PLINK_1e.04 740.11 Osteoarthrosis, localized, primary Both 2070 13762 14 musculoskeletal darkolivegreen 13762, 2070 3441, 523 3440, 532 3440, 533 3441, 482 -0.0253 0.0237 0.287 0.5425 0.975 0.931 1.02 0.0194 0.0671 0.773 0.1119 1.02 0.894 1.16 0.02 0.0673 0.766 0.1158 1.02 0.894 1.16 -0.0923 0.0686 0.179 0.748 0.912 0.797 1.04 PRS_PLINK_1e.04 740.12 Osteoarthrosis, localized, secondary Both 317 3514 14 musculoskeletal darkolivegreen 3514, 317 879, 94 878, 79 878, 67 879, 77 -0.133 0.0579 0.0214 1.669 0.875 0.781 0.98 -0.171 0.159 0.282 0.55 0.843 0.617 1.15 -0.327 0.166 0.0479 1.319 0.721 0.521 0.997 -0.188 0.16 0.24 0.6205 0.829 0.606 1.13 PRS_PLINK_1e.04 740.2 Osteoarthrosis, generalized Both 393 5158 14 musculoskeletal darkolivegreen 5158, 393 1290, 87 1289, 95 1289, 120 1290, 91 0.0517 0.0524 0.324 0.4897 1.05 0.95 1.17 0.0713 0.152 0.64 0.1938 1.07 0.797 1.45 0.297 0.146 0.0412 1.385 1.35 1.01 1.79 -0.00127 0.154 0.993 0.00286 0.999 0.738 1.35 PRS_PLINK_1e.04 740.3 Osteoarthrosis involving more than one site, but not specified as generalized Both 79 1463 14 musculoskeletal darkolivegreen 1463, 79 366, 17 366, 13 365, 26 366, 23 0.154 0.114 0.177 0.7522 1.17 0.933 1.46 -0.248 0.352 0.481 0.3174 0.78 0.391 1.56 0.398 0.308 0.197 0.7066 1.49 0.814 2.72 0.205 0.315 0.515 0.2882 1.23 0.662 2.28 PRS_PLINK_1e.04 740.9 Osteoarthrosis NOS Both 5377 17311 14 musculoskeletal darkolivegreen 17311, 5377 4327, 1329 4328, 1349 4327, 1373 4328, 1326 -0.00474 0.0163 0.771 0.1128 0.995 0.964 1.03 0.0123 0.0463 0.791 0.1018 1.01 0.925 1.11 0.0248 0.0462 0.591 0.2283 1.03 0.936 1.12 -0.021 0.0463 0.651 0.1867 0.979 0.894 1.07 PRS_PLINK_1e.04 741 Symptoms and disorders of the joints Both 3501 18659 14 musculoskeletal darkolivegreen 18659, 3501 4665, 880 4665, 851 4664, 909 4665, 861 -0.00209 0.0184 0.91 0.04102 0.998 0.963 1.03 -0.0309 0.0524 0.556 0.2548 0.97 0.875 1.07 0.0404 0.0517 0.435 0.3617 1.04 0.941 1.15 -0.0164 0.0523 0.754 0.1229 0.984 0.888 1.09 PRS_PLINK_1e.04 741.1 Ankylosis of joint Both 137 1353 14 musculoskeletal darkolivegreen 1353, 137 339, 35 338, 36 338, 31 338, 35 -0.0246 0.0874 0.778 0.1089 0.976 0.822 1.16 0.0607 0.248 0.807 0.09337 1.06 0.654 1.73 -0.127 0.255 0.617 0.2099 0.88 0.534 1.45 -0.0335 0.248 0.893 0.04923 0.967 0.594 1.57 PRS_PLINK_1e.04 741.2 Stiffness of joint Both 593 6341 14 musculoskeletal darkolivegreen 6341, 593 1586, 158 1585, 140 1585, 155 1585, 140 -0.0165 0.0431 0.703 0.1533 0.984 0.904 1.07 -0.119 0.121 0.326 0.4864 0.888 0.701 1.13 -0.017 0.118 0.885 0.05288 0.983 0.78 1.24 -0.125 0.121 0.3 0.5233 0.882 0.696 1.12 PRS_PLINK_1e.04 741.3 Difficulty in walking Both 681 9820 14 musculoskeletal darkolivegreen 9820, 681 2455, 157 2455, 168 2455, 179 2455, 177 0.0348 0.0398 0.382 0.4184 1.04 0.958 1.12 0.0688 0.114 0.546 0.2625 1.07 0.857 1.34 0.136 0.112 0.227 0.6442 1.15 0.919 1.43 0.125 0.113 0.268 0.5713 1.13 0.908 1.41 PRS_PLINK_1e.04 741.4 Joint effusions Both 962 12264 14 musculoskeletal darkolivegreen 12264, 962 3066, 253 3066, 236 3066, 250 3066, 223 -0.036 0.0335 0.283 0.5479 0.965 0.903 1.03 -0.0707 0.0941 0.452 0.3446 0.932 0.775 1.12 -0.00394 0.0928 0.966 0.01498 0.996 0.83 1.19 -0.125 0.0954 0.189 0.7241 0.882 0.732 1.06 PRS_PLINK_1e.04 741.5 Hemarthrosis Both 29 446 14 musculoskeletal darkolivegreen 446, 29 112, 10 111, 4 111, 9 112, 6 -0.142 0.175 0.418 0.379 0.868 0.616 1.22 -0.903 0.579 0.119 0.926 0.405 0.13 1.26 -0.0243 0.462 0.958 0.01858 0.976 0.395 2.41 -0.363 0.494 0.463 0.3346 0.696 0.264 1.83 PRS_PLINK_1e.04 741.6 Villonodular synovitis Both 36 378 14 musculoskeletal darkolivegreen 378, 36 95, 8 94, 11 94, 8 95, 9 0.0729 0.162 0.652 0.1859 1.08 0.784 1.48 0.752 0.497 0.131 0.8844 2.12 0.8 5.62 -0.208 0.521 0.689 0.1616 0.812 0.293 2.25 0.181 0.476 0.704 0.1525 1.2 0.472 3.04 PRS_PLINK_1e.04 742 Derangement of joint, non-traumatic Both 2185 17928 14 musculoskeletal darkolivegreen 17928, 2185 4482, 540 4482, 540 4482, 548 4482, 556 0.0205 0.0228 0.368 0.4337 1.02 0.976 1.07 -0.0101 0.0647 0.876 0.05766 0.99 0.872 1.12 0.0164 0.0645 0.799 0.09726 1.02 0.896 1.15 0.0294 0.0642 0.647 0.1893 1.03 0.908 1.17 PRS_PLINK_1e.04 742.1 Loose body in joint Both 89 937 14 musculoskeletal darkolivegreen 937, 89 235, 28 234, 18 234, 20 234, 23 -0.0476 0.107 0.655 0.1836 0.953 0.774 1.18 -0.417 0.306 0.173 0.7622 0.659 0.361 1.2 -0.309 0.298 0.3 0.5224 0.734 0.409 1.32 -0.183 0.29 0.527 0.278 0.832 0.471 1.47 PRS_PLINK_1e.04 742.2 Pathological, developmental or recurrent dislocation Both 190 1971 14 musculoskeletal darkolivegreen 1971, 190 493, 42 493, 50 492, 51 493, 47 0.0811 0.077 0.292 0.5345 1.08 0.933 1.26 0.18 0.216 0.406 0.3918 1.2 0.784 1.83 0.218 0.214 0.309 0.5095 1.24 0.817 1.89 0.122 0.219 0.577 0.2385 1.13 0.736 1.73 PRS_PLINK_1e.04 742.8 Articular cartilage disorder Both 152 1506 14 musculoskeletal darkolivegreen 1506, 152 377, 38 376, 36 376, 34 377, 44 0.0353 0.0836 0.673 0.1719 1.04 0.879 1.22 -0.084 0.24 0.726 0.139 0.919 0.575 1.47 -0.0958 0.243 0.694 0.1587 0.909 0.564 1.46 0.131 0.23 0.569 0.2447 1.14 0.726 1.79 PRS_PLINK_1e.04 742.9 Other derangement of joint Both 2019 17650 14 musculoskeletal darkolivegreen 17650, 2019 4413, 499 4412, 497 4412, 512 4413, 510 0.0156 0.0236 0.508 0.2942 1.02 0.97 1.06 -0.0127 0.0671 0.85 0.07062 0.987 0.866 1.13 0.0271 0.0667 0.684 0.1648 1.03 0.902 1.17 0.0221 0.0666 0.74 0.131 1.02 0.897 1.16 PRS_PLINK_1e.04 743 Osteoporosis, osteopenia and pathological fracture Both 3446 19463 14 musculoskeletal darkolivegreen 19463, 3446 4865, 874 4866, 827 4865, 902 4866, 843 -0.0167 0.0191 0.382 0.4175 0.983 0.947 1.02 -0.0625 0.0542 0.249 0.6039 0.939 0.845 1.04 0.022 0.0532 0.68 0.1678 1.02 0.921 1.13 -0.0508 0.0538 0.345 0.4627 0.95 0.855 1.06 PRS_PLINK_1e.04 743.1 Osteoporosis Both 1165 8635 14 musculoskeletal darkolivegreen 8635, 1165 2159, 290 2159, 285 2158, 323 2159, 267 0.000332 0.0327 0.992 0.003534 1 0.938 1.07 -0.0202 0.0913 0.825 0.08345 0.98 0.819 1.17 0.103 0.0894 0.248 0.6051 1.11 0.931 1.32 -0.106 0.0933 0.255 0.5938 0.899 0.749 1.08 PRS_PLINK_1e.04 743.11 Osteoporosis NOS Both 1148 8559 14 musculoskeletal darkolivegreen 8559, 1148 2140, 286 2140, 282 2139, 316 2140, 264 -0.00159 0.0329 0.961 0.01707 0.998 0.936 1.06 -0.0201 0.0918 0.827 0.08262 0.98 0.819 1.17 0.0912 0.0902 0.312 0.5058 1.1 0.918 1.31 -0.107 0.0936 0.255 0.5934 0.899 0.748 1.08 PRS_PLINK_1e.04 743.12 Senile osteoporosis Both 209 2009 14 musculoskeletal darkolivegreen 2009, 209 503, 50 502, 57 502, 58 502, 44 -0.0176 0.0725 0.808 0.09267 0.983 0.852 1.13 0.133 0.202 0.512 0.2906 1.14 0.768 1.7 0.135 0.202 0.504 0.2978 1.14 0.77 1.7 -0.131 0.214 0.539 0.268 0.877 0.576 1.33 PRS_PLINK_1e.04 743.13 Other specified osteoporosis Both 96 1262 14 musculoskeletal darkolivegreen 1262, 96 316, 24 315, 23 315, 24 316, 25 -0.00994 0.106 0.925 0.0337 0.99 0.804 1.22 -0.0182 0.294 0.951 0.02202 0.982 0.552 1.75 0.0691 0.296 0.815 0.08877 1.07 0.6 1.91 0.0423 0.288 0.883 0.05394 1.04 0.593 1.83 PRS_PLINK_1e.04 743.2 Pathologic fracture Both 349 4326 14 musculoskeletal darkolivegreen 4326, 349 1082, 89 1081, 87 1081, 98 1082, 75 -0.0543 0.0553 0.326 0.4863 0.947 0.85 1.06 -0.0196 0.155 0.9 0.0459 0.981 0.723 1.33 0.0788 0.152 0.603 0.2195 1.08 0.804 1.46 -0.16 0.161 0.32 0.4942 0.852 0.622 1.17 PRS_PLINK_1e.04 743.21 Pathologic fracture of vertebrae Both 115 1728 14 musculoskeletal darkolivegreen 1728, 115 432, 33 432, 27 432, 29 432, 26 -0.154 0.096 0.11 0.9603 0.858 0.71 1.04 -0.173 0.262 0.51 0.2924 0.841 0.503 1.41 -0.137 0.259 0.598 0.2234 0.872 0.525 1.45 -0.228 0.263 0.387 0.412 0.796 0.475 1.33 PRS_PLINK_1e.04 743.22 Pathologic fracture of femur Both 49 568 14 musculoskeletal darkolivegreen 568, 49 142, 13 142, 12 142, 9 142, 15 0.101 0.148 0.494 0.3061 1.11 0.828 1.48 -0.0307 0.397 0.938 0.0276 0.97 0.445 2.11 -0.316 0.427 0.46 0.3376 0.729 0.316 1.68 0.173 0.381 0.65 0.1872 1.19 0.563 2.51 PRS_PLINK_1e.04 743.4 Stress fracture Both 167 2146 14 musculoskeletal darkolivegreen 2146, 167 537, 45 536, 41 536, 41 537, 40 0.0142 0.0822 0.863 0.06385 1.01 0.863 1.19 -0.104 0.22 0.635 0.1969 0.901 0.585 1.39 -0.0867 0.22 0.694 0.1588 0.917 0.595 1.41 -0.111 0.222 0.617 0.2094 0.895 0.579 1.38 PRS_PLINK_1e.04 743.9 Osteopenia or other disorder of bone and cartilage Both 2596 18128 14 musculoskeletal darkolivegreen 18128, 2596 4532, 664 4532, 640 4532, 662 4532, 630 -0.0283 0.0213 0.184 0.7355 0.972 0.932 1.01 -0.0411 0.0602 0.495 0.3055 0.96 0.853 1.08 -0.00674 0.0598 0.91 0.04087 0.993 0.883 1.12 -0.0613 0.0603 0.309 0.51 0.941 0.836 1.06 PRS_PLINK_1e.04 745 Pain in joint Both 9316 14137 14 musculoskeletal darkolivegreen 14137, 9316 3535, 2365 3534, 2274 3534, 2361 3534, 2315 -0.0103 0.0134 0.444 0.3531 0.99 0.964 1.02 -0.0416 0.038 0.273 0.5634 0.959 0.89 1.03 0.00188 0.0377 0.96 0.01761 1 0.93 1.08 -0.0152 0.0379 0.688 0.1626 0.985 0.914 1.06 PRS_PLINK_1e.04 747 Cardiac and circulatory congenital anomalies Both 768 10507 15 congenital anomalies mediumspringgreen 10507, 768 2627, 204 2627, 202 2626, 193 2627, 168 -0.0608 0.0373 0.103 0.9875 0.941 0.875 1.01 -0.0171 0.103 0.868 0.06144 0.983 0.804 1.2 -0.0536 0.104 0.606 0.2176 0.948 0.773 1.16 -0.2 0.107 0.0627 1.202 0.819 0.663 1.01 PRS_PLINK_1e.04 747.1 Cardiac congenital anomalies Both 552 8098 15 congenital anomalies mediumspringgreen 8098, 552 2025, 146 2024, 136 2024, 142 2025, 128 -0.0213 0.0441 0.63 0.2008 0.979 0.898 1.07 -0.0781 0.123 0.524 0.2805 0.925 0.727 1.18 -0.0245 0.121 0.84 0.0756 0.976 0.769 1.24 -0.132 0.125 0.29 0.5377 0.876 0.687 1.12 PRS_PLINK_1e.04 747.11 Cardiac shunt/ heart septal defect Both 249 3284 15 congenital anomalies mediumspringgreen 3284, 249 821, 74 821, 60 821, 60 821, 55 -0.0939 0.0645 0.146 0.8371 0.91 0.802 1.03 -0.226 0.178 0.205 0.6889 0.798 0.562 1.13 -0.228 0.179 0.203 0.6918 0.796 0.561 1.13 -0.296 0.183 0.105 0.9781 0.744 0.52 1.06 PRS_PLINK_1e.04 747.12 Valvular heart disease/ heart chambers Both 172 3093 15 congenital anomalies mediumspringgreen 3093, 172 774, 42 773, 47 773, 44 773, 39 0.0303 0.0777 0.697 0.1567 1.03 0.885 1.2 0.0936 0.214 0.662 0.1791 1.1 0.722 1.67 0.0617 0.219 0.778 0.1092 1.06 0.693 1.63 -0.0268 0.225 0.905 0.04336 0.974 0.627 1.51 PRS_PLINK_1e.04 747.13 Congenital anomalies of great vessels Both 120 1826 15 congenital anomalies mediumspringgreen 1826, 120 457, 33 456, 32 456, 21 457, 34 0.0137 0.0926 0.882 0.05451 1.01 0.846 1.22 -0.00817 0.251 0.974 0.0114 0.992 0.606 1.62 -0.481 0.279 0.0848 1.072 0.618 0.358 1.07 0.0134 0.25 0.957 0.01896 1.01 0.621 1.65 PRS_PLINK_1e.04 747.2 Congenital anomalies of peripheral vascular system Both 225 2554 15 congenital anomalies mediumspringgreen 2554, 225 639, 58 638, 69 638, 50 639, 47 -0.11 0.0698 0.115 0.9381 0.896 0.781 1.03 0.175 0.185 0.344 0.4637 1.19 0.829 1.71 -0.16 0.198 0.42 0.3767 0.853 0.578 1.26 -0.195 0.201 0.333 0.4778 0.823 0.555 1.22 PRS_PLINK_1e.04 748 Anomalies of respiratory system, congenital Both 49 577 15 congenital anomalies mediumspringgreen 577, 49 145, 9 144, 14 144, 13 144, 13 0.0583 0.14 0.677 0.1691 1.06 0.805 1.4 0.462 0.422 0.274 0.5625 1.59 0.694 3.63 0.367 0.428 0.39 0.4084 1.44 0.624 3.34 0.297 0.442 0.502 0.2993 1.35 0.566 3.2 PRS_PLINK_1e.04 749 Congenital anomalies of face and neck Both 342 3364 15 congenital anomalies mediumspringgreen 3364, 342 841, 92 841, 78 841, 84 841, 88 0.0429 0.0571 0.452 0.3445 1.04 0.933 1.17 -0.166 0.16 0.3 0.5234 0.847 0.618 1.16 -0.089 0.157 0.572 0.243 0.915 0.672 1.25 -0.0387 0.156 0.804 0.09481 0.962 0.709 1.31 PRS_PLINK_1e.04 749.1 Cleft palate Both 77 698 15 congenital anomalies mediumspringgreen 698, 77 175, 21 174, 21 174, 17 175, 18 -0.0273 0.118 0.816 0.08818 0.973 0.773 1.23 0.0428 0.321 0.894 0.04869 1.04 0.556 1.96 -0.188 0.338 0.577 0.2387 0.828 0.427 1.61 -0.0544 0.335 0.871 0.06005 0.947 0.491 1.83 PRS_PLINK_1e.04 749.2 Congenital anomalies of skull and face bones Both 68 713 15 congenital anomalies mediumspringgreen 713, 68 179, 17 178, 20 178, 16 178, 15 0.016 0.131 0.903 0.04423 1.02 0.785 1.31 0.134 0.341 0.695 0.1581 1.14 0.586 2.23 -0.0577 0.352 0.87 0.06064 0.944 0.474 1.88 -0.132 0.356 0.711 0.148 0.877 0.436 1.76 PRS_PLINK_1e.04 750 Digestive congenital anomalies Both 360 4273 15 congenital anomalies mediumspringgreen 4273, 360 1069, 82 1068, 95 1068, 101 1068, 82 0.00762 0.0549 0.89 0.05075 1.01 0.905 1.12 0.156 0.155 0.317 0.4991 1.17 0.861 1.58 0.213 0.154 0.166 0.7788 1.24 0.915 1.67 0.00348 0.161 0.983 0.007554 1 0.732 1.38 PRS_PLINK_1e.04 750.1 Upper gastrointestinal congenital anomalies Both 154 1673 15 congenital anomalies mediumspringgreen 1673, 154 419, 34 418, 45 418, 41 418, 34 -0.0458 0.0841 0.586 0.2319 0.955 0.81 1.13 0.278 0.233 0.232 0.6339 1.32 0.837 2.09 0.2 0.238 0.4 0.3976 1.22 0.766 1.95 -0.00771 0.247 0.975 0.01094 0.992 0.611 1.61 PRS_PLINK_1e.04 750.11 Esophageal atresia/tracheoesophageal fistula Both 49 493 15 congenital anomalies mediumspringgreen 493, 49 124, 7 123, 12 123, 15 123, 15 0.226 0.154 0.144 0.8417 1.25 0.926 1.7 0.429 0.468 0.359 0.4447 1.54 0.614 3.84 0.676 0.445 0.129 0.8902 1.97 0.822 4.7 0.81 0.449 0.0712 1.147 2.25 0.932 5.42 PRS_PLINK_1e.04 750.13 Congenital anomalies of mouth/tongue Both 61 584 15 congenital anomalies mediumspringgreen 584, 61 146, 17 146, 15 146, 15 146, 14 -0.146 0.13 0.261 0.5841 0.864 0.67 1.11 -0.113 0.361 0.755 0.1219 0.893 0.44 1.81 -0.128 0.362 0.723 0.141 0.88 0.433 1.79 -0.157 0.369 0.67 0.1742 0.854 0.415 1.76 PRS_PLINK_1e.04 750.14 Congenital anomalies of esophagus Both 49 544 15 congenital anomalies mediumspringgreen 544, 49 136, 6 136, 13 136, 17 136, 13 0.214 0.149 0.15 0.8233 1.24 0.925 1.66 0.616 0.48 0.199 0.7003 1.85 0.723 4.75 0.971 0.468 0.038 1.421 2.64 1.06 6.61 0.728 0.488 0.136 0.8678 2.07 0.796 5.38 PRS_PLINK_1e.04 750.15 Congenital anomalies of stomach Both 17 213 15 congenital anomalies mediumspringgreen 213, 17 54, 4 53, 6 53, 4 53, 3 -0.0737 0.232 0.75 0.1248 0.929 0.59 1.46 0.631 0.635 0.321 0.4939 1.88 0.541 6.52 0.108 0.643 0.866 0.06241 1.11 0.316 3.93 -0.159 0.698 0.82 0.08606 0.853 0.217 3.35 PRS_PLINK_1e.04 750.2 Lower gastrointestinal congenital anomalies Both 208 2560 15 congenital anomalies mediumspringgreen 2560, 208 640, 47 640, 49 640, 62 640, 50 0.047 0.0723 0.516 0.2875 1.05 0.91 1.21 0.0724 0.21 0.73 0.1368 1.08 0.713 1.62 0.296 0.199 0.138 0.8598 1.34 0.909 1.99 0.0459 0.208 0.825 0.0835 1.05 0.697 1.57 PRS_PLINK_1e.04 750.21 Congenital anomalies of intestine Both 136 1496 15 congenital anomalies mediumspringgreen 1496, 136 374, 31 374, 34 374, 36 374, 35 0.067 0.0891 0.452 0.3447 1.07 0.898 1.27 0.139 0.257 0.588 0.2308 1.15 0.695 1.9 0.227 0.254 0.372 0.4298 1.25 0.763 2.06 0.155 0.256 0.545 0.2639 1.17 0.707 1.93 PRS_PLINK_1e.04 750.22 Congenital anomaly of gallbladder, bile ducts, liver, pancreas Both 74 1091 15 congenital anomalies mediumspringgreen 1091, 74 273, 19 273, 13 272, 27 273, 15 0.0039 0.12 0.974 0.01138 1 0.793 1.27 -0.387 0.351 0.271 0.5673 0.679 0.341 1.35 0.382 0.303 0.207 0.6838 1.47 0.809 2.65 -0.325 0.343 0.344 0.464 0.723 0.369 1.42 PRS_PLINK_1e.04 751 Genitourinary congenital anomalies Both 791 10267 15 congenital anomalies mediumspringgreen 10267, 791 2567, 203 2567, 177 2566, 198 2567, 212 -0.0145 0.0373 0.696 0.1571 0.986 0.916 1.06 -0.141 0.106 0.185 0.7317 0.869 0.705 1.07 -0.0268 0.103 0.795 0.09966 0.974 0.795 1.19 0.042 0.102 0.68 0.1673 1.04 0.854 1.27 PRS_PLINK_1e.04 751.1 Congenital anomalies of genital organs Both 317 3554 15 congenital anomalies mediumspringgreen 3554, 317 889, 74 888, 73 888, 87 889, 83 0.0281 0.0589 0.634 0.1981 1.03 0.916 1.15 -0.0117 0.17 0.945 0.02444 0.988 0.708 1.38 0.15 0.163 0.358 0.4455 1.16 0.843 1.6 0.127 0.166 0.444 0.3522 1.14 0.82 1.57 PRS_PLINK_1e.04 751.11 Congenital anomalies of female genital organs Female 230 2518 15 congenital anomalies mediumspringgreen 2518, 230 630, 56 629, 53 629, 64 630, 57 0.0143 0.07 0.839 0.07645 1.01 0.884 1.16 -0.053 0.197 0.788 0.1034 0.948 0.644 1.4 0.112 0.189 0.555 0.2557 1.12 0.772 1.62 0.0179 0.194 0.926 0.03318 1.02 0.696 1.49 PRS_PLINK_1e.04 751.12 Congenital anomalies of male genital organs Male 73 834 15 congenital anomalies mediumspringgreen 834, 73 209, 13 208, 19 208, 19 209, 22 0.0205 0.118 0.862 0.0643 1.02 0.81 1.29 0.362 0.36 0.315 0.5022 1.44 0.709 2.91 0.395 0.358 0.27 0.5693 1.48 0.736 3 0.506 0.348 0.146 0.8367 1.66 0.839 3.28 PRS_PLINK_1e.04 751.2 Congenital anomalies of urinary system Both 434 6316 15 congenital anomalies mediumspringgreen 6316, 434 1579, 115 1579, 99 1579, 107 1579, 112 -0.0394 0.0492 0.423 0.3732 0.961 0.873 1.06 -0.137 0.141 0.33 0.481 0.872 0.662 1.15 -0.0668 0.138 0.628 0.2022 0.935 0.714 1.23 -0.0117 0.137 0.932 0.03073 0.988 0.756 1.29 PRS_PLINK_1e.04 751.21 Cystic kidney disease Both 258 4236 15 congenital anomalies mediumspringgreen 4236, 258 1059, 73 1059, 53 1059, 60 1059, 72 -0.0325 0.0649 0.616 0.2105 0.968 0.852 1.1 -0.318 0.183 0.0817 1.088 0.727 0.508 1.04 -0.197 0.177 0.265 0.577 0.821 0.581 1.16 -0.00675 0.17 0.968 0.014 0.993 0.712 1.39 PRS_PLINK_1e.04 751.22 Other specified congenital anomalies of kidney Both 110 1486 15 congenital anomalies mediumspringgreen 1486, 110 372, 34 371, 21 371, 30 372, 25 -0.0385 0.0976 0.693 0.1591 0.962 0.795 1.17 -0.451 0.281 0.108 0.9655 0.637 0.367 1.1 -0.0894 0.254 0.725 0.1395 0.914 0.555 1.51 -0.267 0.268 0.32 0.4943 0.766 0.453 1.3 PRS_PLINK_1e.04 751.3 Obstructive genitourinary defect Both 103 1083 15 congenital anomalies mediumspringgreen 1083, 103 271, 29 271, 23 270, 16 271, 35 0.0639 0.1 0.523 0.2812 1.07 0.876 1.3 -0.223 0.284 0.431 0.3652 0.8 0.458 1.4 -0.537 0.313 0.0864 1.063 0.584 0.316 1.08 0.204 0.263 0.438 0.3588 1.23 0.733 2.05 PRS_PLINK_1e.04 752 Nervous system congenital anomalies Both 454 5353 15 congenital anomalies mediumspringgreen 5353, 454 1339, 102 1338, 124 1338, 120 1338, 108 0.0138 0.049 0.779 0.1085 1.01 0.921 1.12 0.199 0.138 0.149 0.8261 1.22 0.931 1.6 0.174 0.139 0.213 0.6718 1.19 0.905 1.56 0.0511 0.142 0.719 0.1432 1.05 0.796 1.39 PRS_PLINK_1e.04 752.1 Neural tube defects Both 340 4135 15 congenital anomalies mediumspringgreen 4135, 340 1034, 81 1034, 90 1033, 90 1034, 79 0.0107 0.0568 0.851 0.07008 1.01 0.904 1.13 0.103 0.158 0.513 0.2897 1.11 0.813 1.51 0.115 0.158 0.467 0.3309 1.12 0.823 1.53 -0.0226 0.163 0.889 0.05095 0.978 0.711 1.34 PRS_PLINK_1e.04 752.11 Spina bifida Both 100 1106 15 congenital anomalies mediumspringgreen 1106, 100 277, 28 276, 22 276, 30 277, 20 -0.00176 0.103 0.986 0.005935 0.998 0.815 1.22 -0.284 0.29 0.327 0.4857 0.753 0.426 1.33 0.0864 0.271 0.749 0.1252 1.09 0.642 1.85 -0.376 0.296 0.204 0.6904 0.687 0.385 1.23 PRS_PLINK_1e.04 752.2 Other specified congenital anomalies of nervous system Both 127 1385 15 congenital anomalies mediumspringgreen 1385, 127 347, 31 346, 37 346, 28 346, 31 -0.0523 0.0906 0.564 0.2488 0.949 0.795 1.13 0.145 0.25 0.562 0.25 1.16 0.709 1.88 -0.105 0.265 0.692 0.1599 0.9 0.535 1.51 -0.0285 0.259 0.913 0.03972 0.972 0.585 1.62 PRS_PLINK_1e.04 753 Congenital anomalies of the eye Both 81 981 15 congenital anomalies mediumspringgreen 981, 81 246, 21 245, 20 245, 21 245, 19 -0.0546 0.114 0.633 0.1987 0.947 0.757 1.18 -0.0212 0.316 0.946 0.02388 0.979 0.527 1.82 0.00728 0.308 0.981 0.008261 1.01 0.55 1.84 -0.0904 0.316 0.775 0.1107 0.914 0.491 1.7 PRS_PLINK_1e.04 753.1 Congenital cataract and lens anomalies Both 22 261 15 congenital anomalies mediumspringgreen 261, 22 66, 10 65, 3 65, 7 65, 2 -0.321 0.214 0.134 0.8729 0.725 0.476 1.1 -0.84 0.595 0.158 0.8021 0.432 0.135 1.38 -0.155 0.495 0.754 0.1225 0.857 0.325 2.26 -1.69 0.68 0.013 1.885 0.185 0.0487 0.701 PRS_PLINK_1e.04 753.2 Congenital anomalies of posterior segment of eye Both 28 276 15 congenital anomalies mediumspringgreen 276, 28 69, 6 69, 7 69, 7 69, 8 0.0881 0.204 0.666 0.1763 1.09 0.732 1.63 0.225 0.551 0.683 0.1659 1.25 0.425 3.69 0.172 0.557 0.757 0.1208 1.19 0.399 3.54 0.297 0.535 0.579 0.2371 1.35 0.471 3.84 PRS_PLINK_1e.04 754 Congenital musculoskeletal deformities of spine Both 407 5087 15 congenital anomalies mediumspringgreen 5087, 407 1272, 99 1272, 112 1271, 104 1272, 92 0.00253 0.0514 0.961 0.01737 1 0.906 1.11 0.135 0.143 0.344 0.4629 1.14 0.865 1.51 0.0722 0.145 0.619 0.2082 1.07 0.808 1.43 -0.0478 0.15 0.75 0.1252 0.953 0.711 1.28 PRS_PLINK_1e.04 754.1 Lumbosacral spondylolysis, congenital Both 58 627 15 congenital anomalies mediumspringgreen 627, 58 157, 11 157, 15 156, 16 157, 16 0.102 0.133 0.444 0.3531 1.11 0.854 1.44 0.492 0.401 0.22 0.6585 1.64 0.746 3.59 0.451 0.399 0.258 0.5879 1.57 0.718 3.43 0.542 0.406 0.182 0.7406 1.72 0.776 3.81 PRS_PLINK_1e.04 754.2 Spondylolisthesis, congenital Both 185 2290 15 congenital anomalies mediumspringgreen 2290, 185 573, 43 572, 51 572, 49 573, 42 0.0305 0.0778 0.695 0.1581 1.03 0.885 1.2 0.195 0.214 0.362 0.441 1.21 0.799 1.85 0.107 0.215 0.618 0.2091 1.11 0.73 1.7 -0.0278 0.223 0.901 0.04547 0.973 0.629 1.5 PRS_PLINK_1e.04 755 Congenital anomalies of limbs Both 406 4286 15 congenital anomalies mediumspringgreen 4286, 406 1072, 117 1071, 87 1071, 93 1072, 109 -0.0199 0.0512 0.697 0.1567 0.98 0.887 1.08 -0.294 0.147 0.0453 1.344 0.745 0.558 0.994 -0.234 0.145 0.105 0.9773 0.791 0.596 1.05 -0.0586 0.139 0.674 0.1713 0.943 0.718 1.24 PRS_PLINK_1e.04 755.1 Congenital deformities of feet Both 176 1897 15 congenital anomalies mediumspringgreen 1897, 176 475, 47 474, 46 474, 37 474, 46 -0.04 0.077 0.603 0.2196 0.961 0.826 1.12 -0.0116 0.214 0.957 0.01914 0.988 0.649 1.5 -0.242 0.226 0.284 0.5462 0.785 0.505 1.22 -0.0263 0.215 0.903 0.0444 0.974 0.639 1.48 PRS_PLINK_1e.04 755.4 Congenital anomalies of upper limb, including shoulder girdle Both 38 409 15 congenital anomalies mediumspringgreen 409, 38 103, 9 102, 4 102, 11 102, 14 0.228 0.165 0.167 0.7778 1.26 0.909 1.74 -0.675 0.555 0.224 0.6497 0.509 0.171 1.51 0.257 0.453 0.571 0.2432 1.29 0.532 3.14 0.419 0.427 0.327 0.4856 1.52 0.658 3.51 PRS_PLINK_1e.04 755.6 Other congenital anomalies of lower limb, including pelvic girdle Both 213 2143 15 congenital anomalies mediumspringgreen 2143, 213 536, 68 536, 40 535, 45 536, 60 -0.0758 0.0731 0.3 0.5228 0.927 0.803 1.07 -0.513 0.206 0.0127 1.896 0.598 0.4 0.896 -0.421 0.201 0.0359 1.445 0.656 0.443 0.973 -0.107 0.186 0.565 0.2478 0.899 0.624 1.29 PRS_PLINK_1e.04 755.61 Congenital hip dysplasia and deformity Both 129 1318 15 congenital anomalies mediumspringgreen 1318, 129 330, 41 329, 26 329, 28 330, 34 -0.1 0.0918 0.275 0.5605 0.905 0.756 1.08 -0.395 0.257 0.124 0.9074 0.674 0.407 1.11 -0.352 0.255 0.168 0.7758 0.703 0.427 1.16 -0.176 0.243 0.47 0.3279 0.839 0.521 1.35 PRS_PLINK_1e.04 756 Other congenital musculoskeletal anomalies Both 662 7290 15 congenital anomalies mediumspringgreen 7290, 662 1822, 170 1822, 165 1822, 161 1823, 166 -0.0204 0.0409 0.618 0.2092 0.98 0.904 1.06 -0.0303 0.114 0.79 0.1024 0.97 0.776 1.21 -0.0533 0.114 0.641 0.193 0.948 0.758 1.19 -0.0152 0.114 0.894 0.04874 0.985 0.788 1.23 PRS_PLINK_1e.04 756.1 Congenital anomalies of abdominal wall; diaphram Both 39 395 15 congenital anomalies mediumspringgreen 395, 39 99, 15 99, 8 98, 11 99, 5 -0.2 0.171 0.24 0.6201 0.818 0.586 1.14 -0.547 0.447 0.221 0.6554 0.579 0.241 1.39 -0.263 0.407 0.518 0.2855 0.769 0.347 1.71 -1.01 0.506 0.0468 1.33 0.366 0.136 0.986 PRS_PLINK_1e.04 756.2 Pectus and other congenital anomalies of ribs/sternum Both 49 505 15 congenital anomalies mediumspringgreen 505, 49 126, 12 126, 17 126, 7 126, 13 0.0111 0.148 0.94 0.02675 1.01 0.757 1.35 0.224 0.383 0.558 0.2532 1.25 0.591 2.65 -0.503 0.461 0.275 0.5604 0.605 0.245 1.49 0.0939 0.41 0.819 0.08686 1.1 0.492 2.45 PRS_PLINK_1e.04 756.3 Congenital anomalies of muscle, tendon, fascia, and connective tissue Both 173 1815 15 congenital anomalies mediumspringgreen 1815, 173 454, 35 454, 50 453, 43 454, 45 0.0614 0.0803 0.445 0.3521 1.06 0.909 1.24 0.36 0.227 0.113 0.9484 1.43 0.919 2.24 0.22 0.234 0.345 0.4618 1.25 0.789 1.97 0.224 0.231 0.333 0.4774 1.25 0.795 1.97 PRS_PLINK_1e.04 756.5 Congenital osteodystrophies Both 437 4931 15 congenital anomalies mediumspringgreen 4931, 437 1232, 117 1233, 105 1232, 113 1233, 102 -0.065 0.0503 0.197 0.7066 0.937 0.849 1.03 -0.126 0.14 0.368 0.4346 0.881 0.67 1.16 -0.0374 0.137 0.785 0.105 0.963 0.736 1.26 -0.129 0.14 0.36 0.4436 0.879 0.668 1.16 PRS_PLINK_1e.04 757 Congenital anomalies of the integument Both 156 1698 15 congenital anomalies mediumspringgreen 1698, 156 424, 36 424, 48 424, 33 425, 39 0.0335 0.0837 0.689 0.1617 1.03 0.878 1.22 0.278 0.228 0.223 0.6521 1.32 0.845 2.06 -0.0575 0.246 0.815 0.08868 0.944 0.583 1.53 0.103 0.238 0.664 0.1778 1.11 0.696 1.77 PRS_PLINK_1e.04 758 Chromosomal anomalies and genetic disorders Both 90 1085 15 congenital anomalies mediumspringgreen 1085, 90 272, 19 271, 23 271, 21 271, 27 0.121 0.111 0.278 0.5552 1.13 0.907 1.4 0.239 0.312 0.445 0.352 1.27 0.689 2.34 0.0812 0.318 0.798 0.09777 1.08 0.582 2.02 0.362 0.302 0.231 0.6366 1.44 0.795 2.59 PRS_PLINK_1e.04 758.1 Chromosomal anomalies Both 64 800 15 congenital anomalies mediumspringgreen 800, 64 200, 15 200, 16 200, 12 200, 21 0.137 0.129 0.286 0.5434 1.15 0.891 1.48 0.0163 0.359 0.964 0.01608 1.02 0.503 2.05 -0.269 0.379 0.479 0.32 0.765 0.364 1.61 0.369 0.34 0.277 0.5573 1.45 0.743 2.82 PRS_PLINK_1e.04 759 Other and unspecified congenital anomalies Both 304 3303 15 congenital anomalies mediumspringgreen 3303, 304 826, 76 826, 71 825, 75 826, 82 0.013 0.0597 0.828 0.08185 1.01 0.901 1.14 -0.0588 0.17 0.73 0.1368 0.943 0.675 1.32 -0.00764 0.168 0.964 0.01602 0.992 0.713 1.38 0.0806 0.165 0.625 0.2041 1.08 0.785 1.5 PRS_PLINK_1e.04 759.1 Anomalies of endocrine glands, congenital Both 43 390 15 congenital anomalies mediumspringgreen 390, 43 98, 15 97, 6 97, 11 98, 11 -0.164 0.152 0.283 0.5487 0.849 0.63 1.14 -0.746 0.474 0.115 0.9379 0.474 0.187 1.2 -0.19 0.426 0.656 0.1829 0.827 0.359 1.91 -0.271 0.408 0.507 0.2953 0.762 0.342 1.7 PRS_PLINK_1e.04 760 Back pain Both 6822 16617 17 symptoms purple 16617, 6822 4155, 1627 4154, 1707 4154, 1753 4154, 1734 0.0177 0.0145 0.222 0.6544 1.02 0.989 1.05 0.0432 0.0414 0.297 0.5279 1.04 0.963 1.13 0.0698 0.0412 0.09 1.046 1.07 0.989 1.16 0.0553 0.0413 0.18 0.7442 1.06 0.975 1.15 PRS_PLINK_1e.04 761 Cervicalgia Both 2813 20227 17 symptoms purple 20227, 2813 5056, 672 5057, 706 5056, 719 5057, 716 0.0209 0.0203 0.303 0.5193 1.02 0.981 1.06 0.0433 0.0578 0.454 0.3434 1.04 0.932 1.17 0.062 0.0575 0.28 0.5521 1.06 0.951 1.19 0.0545 0.0575 0.343 0.4643 1.06 0.943 1.18 PRS_PLINK_1e.04 763 Thoracic or lumbosacral neuritis or radiculitis, unspecified Both 1294 15417 17 symptoms purple 15417, 1294 3855, 306 3854, 340 3854, 327 3854, 320 0.0252 0.029 0.384 0.4161 1.03 0.969 1.09 0.1 0.0819 0.222 0.654 1.11 0.941 1.3 0.0641 0.0826 0.438 0.3586 1.07 0.907 1.25 0.0442 0.083 0.594 0.2259 1.05 0.888 1.23 PRS_PLINK_1e.04 764 Sciatica Both 1261 15362 17 symptoms purple 15362, 1261 3841, 308 3840, 319 3840, 322 3841, 311 0.0115 0.0292 0.694 0.1589 1.01 0.955 1.07 0.036 0.0829 0.664 0.1776 1.04 0.881 1.22 0.0484 0.0828 0.558 0.253 1.05 0.892 1.23 0.0147 0.0834 0.86 0.06559 1.01 0.862 1.2 PRS_PLINK_1e.04 765 Cervical radiculitis Both 734 8442 17 symptoms purple 8442, 734 2111, 191 2110, 166 2110, 185 2111, 192 0.00516 0.0387 0.894 0.04865 1.01 0.932 1.08 -0.126 0.11 0.255 0.594 0.882 0.711 1.09 -0.0225 0.107 0.834 0.07895 0.978 0.792 1.21 0.0246 0.107 0.818 0.08742 1.02 0.832 1.26 PRS_PLINK_1e.04 766 Neuralgia, neuritis, and radiculitis NOS Both 2027 18767 17 symptoms purple 18767, 2027 4692, 485 4692, 518 4691, 491 4692, 532 0.0188 0.0235 0.425 0.3718 1.02 0.973 1.07 0.0663 0.0664 0.318 0.4971 1.07 0.938 1.22 0.0098 0.0673 0.884 0.05346 1.01 0.885 1.15 0.0896 0.0661 0.176 0.7554 1.09 0.961 1.25 PRS_PLINK_1e.04 767 Cervicocranial/Cervicobrachial syndrome Both 41 547 17 symptoms purple 547, 41 137, 12 137, 6 136, 8 137, 15 0.198 0.161 0.22 0.6568 1.22 0.888 1.67 -0.759 0.477 0.112 0.9525 0.468 0.184 1.19 -0.416 0.436 0.34 0.4683 0.66 0.281 1.55 0.171 0.394 0.664 0.1776 1.19 0.548 2.57 PRS_PLINK_1e.04 769 Nonallopathic lesions NEC Both 461 5347 17 symptoms purple 5347, 461 1337, 118 1337, 108 1336, 112 1337, 123 -0.00569 0.0485 0.907 0.04251 0.994 0.904 1.09 -0.0929 0.138 0.5 0.3013 0.911 0.696 1.19 -0.0561 0.136 0.681 0.167 0.945 0.724 1.24 0.0322 0.134 0.809 0.09179 1.03 0.795 1.34 PRS_PLINK_1e.04 770 Myalgia and myositis unspecified Both 2371 17442 17 symptoms purple 17442, 2371 4361, 600 4360, 590 4360, 580 4361, 600 -0.00641 0.0221 0.772 0.1123 0.994 0.951 1.04 -0.0244 0.0621 0.695 0.1581 0.976 0.864 1.1 -0.0436 0.0623 0.484 0.3148 0.957 0.847 1.08 -0.00729 0.062 0.906 0.0427 0.993 0.879 1.12 PRS_PLINK_1e.04 771 Musculoskeletal symptoms referable to limbs Both 1786 18564 17 symptoms purple 18564, 1786 4641, 445 4641, 457 4641, 442 4641, 441 -0.0165 0.0247 0.504 0.2978 0.984 0.937 1.03 0.0304 0.0697 0.663 0.1784 1.03 0.899 1.18 -0.00498 0.0703 0.944 0.02524 0.995 0.867 1.14 -0.00935 0.0703 0.894 0.04858 0.991 0.863 1.14 PRS_PLINK_1e.04 771.1 Swelling of limb Both 1786 18493 17 symptoms purple 18493, 1786 4624, 424 4623, 444 4623, 473 4623, 444 0.0277 0.0249 0.267 0.5742 1.03 0.979 1.08 0.0548 0.0711 0.441 0.3556 1.06 0.919 1.21 0.112 0.0701 0.112 0.9512 1.12 0.974 1.28 0.0418 0.0711 0.557 0.2544 1.04 0.907 1.2 PRS_PLINK_1e.04 771.2 Cramp of limb Both 314 4653 17 symptoms purple 4653, 314 1164, 76 1163, 75 1163, 98 1163, 65 -0.0289 0.0587 0.622 0.2064 0.971 0.866 1.09 0.0016 0.167 0.992 0.003334 1 0.722 1.39 0.267 0.157 0.0897 1.047 1.31 0.96 1.78 -0.133 0.172 0.437 0.3592 0.875 0.625 1.23 PRS_PLINK_1e.04 772 Symptoms of the muscles Both 901 9877 17 symptoms purple 9877, 901 2470, 241 2469, 221 2469, 219 2469, 220 0.00295 0.0348 0.932 0.03039 1 0.937 1.07 -0.079 0.0971 0.416 0.381 0.924 0.764 1.12 -0.0949 0.0973 0.33 0.4818 0.909 0.752 1.1 -0.092 0.0972 0.344 0.4632 0.912 0.754 1.1 PRS_PLINK_1e.04 772.1 Muscular wasting and disuse atrophy Both 193 2274 17 symptoms purple 2274, 193 569, 57 568, 44 568, 49 569, 43 -0.0649 0.0734 0.376 0.4243 0.937 0.811 1.08 -0.295 0.207 0.154 0.8133 0.744 0.496 1.12 -0.185 0.202 0.359 0.4454 0.831 0.559 1.23 -0.294 0.208 0.157 0.8029 0.745 0.496 1.12 PRS_PLINK_1e.04 772.2 Spasm of muscle Both 991 12250 17 symptoms purple 12250, 991 3062, 234 3062, 242 3062, 251 3063, 264 0.049 0.0332 0.14 0.8536 1.05 0.984 1.12 0.0311 0.0949 0.743 0.1288 1.03 0.856 1.24 0.0703 0.0942 0.455 0.3417 1.07 0.892 1.29 0.12 0.0931 0.198 0.7034 1.13 0.939 1.35 PRS_PLINK_1e.04 772.3 Muscle weakness Both 904 12450 17 symptoms purple 12450, 904 3113, 223 3112, 234 3112, 229 3113, 218 -0.0137 0.0343 0.689 0.1615 0.986 0.922 1.05 0.0538 0.0966 0.577 0.2386 1.06 0.873 1.28 0.0305 0.0971 0.754 0.1229 1.03 0.852 1.25 -0.014 0.0983 0.887 0.05207 0.986 0.813 1.2 PRS_PLINK_1e.04 772.4 Rhabdomyolysis Both 32 743 17 symptoms purple 743, 32 186, 11 186, 8 185, 6 186, 7 -0.343 0.161 0.0327 1.485 0.71 0.518 0.972 -0.184 0.436 0.673 0.1718 0.832 0.354 1.96 -0.416 0.475 0.381 0.4192 0.66 0.26 1.67 -0.387 0.452 0.392 0.4068 0.679 0.28 1.65 PRS_PLINK_1e.04 772.6 Facial weakness Both 124 1943 17 symptoms purple 1943, 124 486, 35 486, 29 485, 36 486, 24 -0.0859 0.0933 0.357 0.4471 0.918 0.764 1.1 -0.171 0.253 0.5 0.3008 0.843 0.513 1.38 0.0232 0.241 0.923 0.03471 1.02 0.639 1.64 -0.324 0.266 0.224 0.6488 0.724 0.429 1.22 PRS_PLINK_1e.04 780 Hypothermia/Chills Both 135 1996 17 symptoms purple 1996, 135 499, 43 499, 31 499, 28 499, 33 -0.113 0.0872 0.196 0.7085 0.893 0.753 1.06 -0.311 0.238 0.193 0.715 0.733 0.459 1.17 -0.409 0.244 0.0941 1.026 0.664 0.411 1.07 -0.297 0.237 0.21 0.6769 0.743 0.467 1.18 PRS_PLINK_1e.04 781 Symptoms involving nervous and musculoskeletal systems Both 815 11404 17 symptoms purple 11404, 815 2851, 194 2851, 191 2851, 225 2851, 205 0.00342 0.0366 0.925 0.03364 1 0.934 1.08 -0.0152 0.105 0.885 0.05305 0.985 0.802 1.21 0.145 0.101 0.151 0.8211 1.16 0.948 1.41 0.046 0.104 0.657 0.1826 1.05 0.855 1.28 PRS_PLINK_1e.04 781.1 Loss of height Both 32 395 17 symptoms purple 395, 32 99, 9 99, 6 98, 7 99, 10 0.188 0.175 0.282 0.5494 1.21 0.857 1.7 -0.603 0.51 0.237 0.6253 0.547 0.201 1.49 -0.128 0.484 0.791 0.1018 0.88 0.34 2.27 0.173 0.453 0.703 0.1533 1.19 0.49 2.89 PRS_PLINK_1e.04 781.2 Abnormal posture Both 23 260 17 symptoms purple 260, 23 65, 12 65, 4 65, 2 65, 5 -0.367 0.193 0.0568 1.245 0.693 0.475 1.01 -0.854 0.558 0.126 0.9009 0.426 0.143 1.27 -1.57 0.656 0.0165 1.782 0.208 0.0574 0.751 -0.881 0.532 0.0979 1.009 0.414 0.146 1.18 PRS_PLINK_1e.04 782.3 Edema Both 1489 18570 17 symptoms purple 18570, 1489 4643, 376 4642, 367 4642, 391 4643, 354 -0.0152 0.027 0.574 0.2409 0.985 0.934 1.04 -0.0236 0.0762 0.757 0.1208 0.977 0.841 1.13 0.0353 0.0752 0.639 0.1944 1.04 0.894 1.2 -0.0674 0.0769 0.38 0.42 0.935 0.804 1.09 PRS_PLINK_1e.04 782.6 Pallor and flushing Both 470 5207 17 symptoms purple 5207, 470 1302, 136 1302, 107 1301, 101 1302, 126 -0.0603 0.0481 0.21 0.6785 0.941 0.857 1.03 -0.228 0.135 0.0905 1.043 0.796 0.611 1.04 -0.301 0.136 0.0276 1.559 0.74 0.567 0.967 -0.0759 0.129 0.557 0.2543 0.927 0.72 1.19 PRS_PLINK_1e.04 783 Fever of unknown origin Both 2068 21167 17 symptoms purple 21167, 2068 5292, 524 5292, 517 5291, 533 5292, 493 -0.0241 0.023 0.295 0.53 0.976 0.933 1.02 -0.0127 0.065 0.846 0.07288 0.987 0.869 1.12 0.022 0.0645 0.733 0.1351 1.02 0.901 1.16 -0.0603 0.0657 0.359 0.4454 0.941 0.828 1.07 PRS_PLINK_1e.04 783.1 Postprocedural fever Both 104 1472 17 symptoms purple 1472, 104 368, 23 368, 22 368, 32 368, 27 0.0828 0.103 0.419 0.3776 1.09 0.889 1.33 -0.0119 0.298 0.968 0.01403 0.988 0.551 1.77 0.354 0.277 0.201 0.696 1.42 0.828 2.45 0.149 0.286 0.601 0.2213 1.16 0.664 2.03 PRS_PLINK_1e.04 785 Abdominal pain Both 7292 16153 17 symptoms purple 16153, 7292 4039, 1826 4038, 1834 4038, 1819 4038, 1812 -0.00377 0.0143 0.792 0.1011 0.996 0.969 1.02 -0.00306 0.0403 0.939 0.02711 0.997 0.921 1.08 -0.0112 0.0406 0.783 0.106 0.989 0.913 1.07 -0.0131 0.0405 0.746 0.1275 0.987 0.912 1.07 PRS_PLINK_1e.04 788 Syncope and collapse Both 1343 17366 17 symptoms purple 17366, 1343 4342, 323 4341, 328 4341, 361 4342, 331 0.00305 0.0284 0.914 0.03882 1 0.949 1.06 0.0149 0.0811 0.854 0.06858 1.02 0.866 1.19 0.111 0.0794 0.161 0.792 1.12 0.957 1.31 0.023 0.081 0.776 0.1099 1.02 0.873 1.2 PRS_PLINK_1e.04 789 Nausea and vomiting Both 4627 18769 17 symptoms purple 18769, 4627 4693, 1174 4692, 1162 4692, 1143 4692, 1147 -0.0212 0.0167 0.204 0.6909 0.979 0.948 1.01 -0.0197 0.0468 0.675 0.171 0.981 0.895 1.07 -0.0439 0.047 0.351 0.455 0.957 0.873 1.05 -0.0393 0.0471 0.404 0.3932 0.961 0.877 1.05 PRS_PLINK_1e.04 789.1 Persistent vomiting Both 313 4461 17 symptoms purple 4461, 313 1116, 90 1115, 70 1115, 78 1115, 75 -0.105 0.0579 0.0694 1.158 0.9 0.804 1.01 -0.254 0.164 0.121 0.9166 0.776 0.563 1.07 -0.154 0.159 0.333 0.478 0.858 0.628 1.17 -0.195 0.161 0.226 0.6466 0.823 0.601 1.13 PRS_PLINK_1e.04 790 Nonspecific findings on examination of blood Both 578 10151 17 symptoms purple 10151, 578 2537, 127 2538, 154 2537, 145 2538, 152 0.0648 0.043 0.131 0.8813 1.07 0.981 1.16 0.189 0.122 0.124 0.9081 1.21 0.95 1.53 0.147 0.124 0.236 0.6267 1.16 0.908 1.48 0.187 0.123 0.128 0.894 1.21 0.948 1.53 PRS_PLINK_1e.04 790.1 Elevated sedimentation rate Both 69 1144 17 symptoms purple 1144, 69 286, 19 286, 12 286, 18 286, 20 0.0303 0.123 0.806 0.09385 1.03 0.81 1.31 -0.503 0.363 0.167 0.778 0.605 0.297 1.23 0.0204 0.328 0.95 0.02215 1.02 0.537 1.94 0.14 0.32 0.662 0.1789 1.15 0.615 2.15 PRS_PLINK_1e.04 790.6 Other abnormal blood chemistry Both 2345 20299 17 symptoms purple 20299, 2345 5074, 539 5075, 575 5074, 612 5075, 619 0.0558 0.0221 0.0115 1.939 1.06 1.01 1.1 0.0733 0.0635 0.249 0.6042 1.08 0.95 1.22 0.128 0.0628 0.0414 1.383 1.14 1.01 1.29 0.147 0.0626 0.0188 1.725 1.16 1.02 1.31 PRS_PLINK_1e.04 790.8 Elevated C-reactive protein (CRP) Both 120 1739 17 symptoms purple 1739, 120 434, 27 435, 28 434, 33 435, 32 0.0881 0.0944 0.351 0.4552 1.09 0.908 1.31 0.0299 0.269 0.912 0.04019 1.03 0.608 1.75 0.229 0.261 0.38 0.4201 1.26 0.754 2.1 0.144 0.265 0.586 0.2322 1.16 0.687 1.94 PRS_PLINK_1e.04 790.9 Abnormal arterial blood gases Both 36 641 17 symptoms purple 641, 36 161, 10 160, 14 160, 4 160, 8 -0.12 0.161 0.455 0.3416 0.887 0.646 1.22 0.379 0.407 0.352 0.4533 1.46 0.657 3.25 -0.892 0.532 0.0934 1.03 0.41 0.145 1.16 -0.12 0.453 0.791 0.1016 0.887 0.365 2.16 PRS_PLINK_1e.04 791 Gangrene Both 53 1223 17 symptoms purple 1223, 53 306, 13 306, 17 305, 10 306, 13 -0.125 0.133 0.346 0.4608 0.882 0.68 1.14 0.309 0.355 0.385 0.415 1.36 0.679 2.73 -0.244 0.393 0.535 0.2714 0.784 0.363 1.69 0.0214 0.376 0.955 0.02015 1.02 0.489 2.14 PRS_PLINK_1e.04 792 Abnormal Papanicolaou smear of cervix and cervical HPV Female 1741 8578 11 genitourinary black 8578, 1741 2145, 452 2144, 452 2144, 389 2145, 447 -0.00556 0.0263 0.833 0.07951 0.994 0.944 1.05 0.00867 0.0734 0.906 0.04288 1.01 0.874 1.16 -0.145 0.0757 0.0545 1.264 0.865 0.745 1 -0.0108 0.0735 0.883 0.05404 0.989 0.856 1.14 PRS_PLINK_1e.04 792.1 Papanicolaou smear of cervix or vagina with atypical squamous cells Female 744 6486 11 genitourinary black 6486, 744 1622, 183 1621, 192 1621, 159 1622, 209 0.036 0.0387 0.353 0.4521 1.04 0.961 1.12 0.0644 0.109 0.555 0.2558 1.07 0.861 1.32 -0.138 0.114 0.226 0.6459 0.871 0.697 1.09 0.134 0.107 0.21 0.6783 1.14 0.927 1.41 PRS_PLINK_1e.04 794 Abnormal results of other function studies (bladder, pancreas, placenta, spleen, etc) Both 223 2254 17 symptoms purple 2254, 223 564, 51 563, 49 563, 59 564, 64 0.0498 0.0711 0.484 0.3154 1.05 0.914 1.21 -0.0536 0.207 0.795 0.09946 0.948 0.632 1.42 0.141 0.198 0.476 0.3228 1.15 0.782 1.7 0.224 0.196 0.252 0.5978 1.25 0.853 1.84 PRS_PLINK_1e.04 795 Other and nonspecific abnormal cytological, histological and immunological findings Both 1240 11473 17 symptoms purple 11473, 1240 2868, 333 2868, 306 2868, 308 2868, 293 -0.0273 0.0302 0.365 0.4373 0.973 0.917 1.03 -0.0813 0.0835 0.33 0.4812 0.922 0.783 1.09 -0.0754 0.0832 0.365 0.4378 0.927 0.788 1.09 -0.13 0.0844 0.122 0.9129 0.878 0.744 1.04 PRS_PLINK_1e.04 795.8 Abnormal tumor markers Both 568 5220 17 symptoms purple 5220, 568 1305, 141 1305, 146 1305, 133 1305, 148 0.0136 0.0437 0.756 0.1214 1.01 0.931 1.1 0.0271 0.124 0.827 0.08249 1.03 0.806 1.31 -0.0527 0.127 0.678 0.1688 0.949 0.74 1.22 0.0529 0.124 0.669 0.1748 1.05 0.827 1.34 PRS_PLINK_1e.04 795.81 Elevated carcinoembryonic antigen [CEA] Both 20 215 17 symptoms purple 215, 20 54, 4 54, 7 53, 4 54, 5 0.00471 0.242 0.984 0.006814 1 0.626 1.61 0.25 0.63 0.691 0.1605 1.28 0.374 4.41 0.141 0.654 0.829 0.08139 1.15 0.32 4.15 -0.00676 0.662 0.992 0.003557 0.993 0.272 3.63 PRS_PLINK_1e.04 795.82 Elevated cancer antigen 125 [CA 125] Both 84 837 17 symptoms purple 837, 84 210, 15 209, 17 209, 25 209, 27 0.152 0.114 0.182 0.7397 1.16 0.931 1.46 0.128 0.352 0.717 0.1443 1.14 0.569 2.27 0.567 0.335 0.0907 1.043 1.76 0.914 3.4 0.649 0.332 0.0508 1.294 1.91 0.998 3.67 PRS_PLINK_1e.04 796 Elevated prostate specific antigen [PSA] Male 641 3602 11 genitourinary black 3602, 641 901, 162 900, 183 900, 136 901, 160 -0.00814 0.0426 0.848 0.0714 0.992 0.912 1.08 0.108 0.121 0.371 0.4308 1.11 0.879 1.41 -0.192 0.128 0.134 0.8735 0.825 0.642 1.06 -0.0217 0.123 0.86 0.06549 0.979 0.769 1.25 PRS_PLINK_1e.04 797 Shock Both 82 2361 17 symptoms purple 2361, 82 591, 22 590, 16 590, 22 590, 22 0.0834 0.109 0.444 0.353 1.09 0.878 1.35 -0.265 0.319 0.407 0.3906 0.767 0.41 1.43 -0.00709 0.295 0.981 0.008409 0.993 0.557 1.77 0.00468 0.295 0.987 0.00554 1 0.564 1.79 PRS_PLINK_1e.04 797.1 Cardiogenic shock Both 18 885 17 symptoms purple 885, 18 222, 4 221, 5 221, 5 221, 4 0.0662 0.218 0.761 0.1184 1.07 0.697 1.64 0.289 0.575 0.616 0.2106 1.33 0.432 4.12 0.081 0.587 0.89 0.05052 1.08 0.343 3.42 -0.0844 0.59 0.886 0.05239 0.919 0.289 2.92 PRS_PLINK_1e.04 798 Malaise and fatigue Both 4596 18829 17 symptoms purple 18829, 4596 4708, 1173 4707, 1134 4707, 1155 4707, 1133 -0.0119 0.0167 0.475 0.3229 0.988 0.956 1.02 -0.0387 0.047 0.41 0.3872 0.962 0.877 1.05 -0.0242 0.0468 0.605 0.218 0.976 0.89 1.07 -0.0413 0.0469 0.379 0.4213 0.96 0.875 1.05 PRS_PLINK_1e.04 798.1 Chronic fatigue syndrome Both 744 8939 17 symptoms purple 8939, 744 2235, 197 2235, 176 2234, 175 2235, 196 -0.00227 0.0382 0.953 0.02104 0.998 0.926 1.08 -0.109 0.108 0.312 0.5063 0.897 0.726 1.11 -0.113 0.108 0.296 0.5292 0.893 0.723 1.1 0.0115 0.105 0.913 0.03952 1.01 0.823 1.24 PRS_PLINK_1e.04 800 Fracture of lower limb Both 1024 11458 18 injuries & poisonings gray50 11458, 1024 2865, 255 2864, 252 2864, 264 2865, 253 0.0105 0.0328 0.75 0.1252 1.01 0.948 1.08 -0.0107 0.0925 0.908 0.04197 0.989 0.825 1.19 0.0359 0.0915 0.694 0.1584 1.04 0.866 1.24 -0.0115 0.0924 0.901 0.04509 0.989 0.825 1.18 PRS_PLINK_1e.04 800.1 Fracture of neck of femur Both 155 1974 18 injuries & poisonings gray50 1974, 155 494, 35 493, 40 493, 46 494, 34 0.054 0.0822 0.511 0.2915 1.06 0.898 1.24 0.115 0.236 0.628 0.2024 1.12 0.706 1.78 0.265 0.231 0.252 0.5992 1.3 0.829 2.05 -8.32e-05 0.243 1 0.0001186 1 0.621 1.61 PRS_PLINK_1e.04 800.2 Fracture of unspecified part of femur Both 234 2901 18 injuries & poisonings gray50 2901, 234 726, 57 725, 64 725, 57 725, 56 0.013 0.0675 0.848 0.07175 1.01 0.888 1.16 0.121 0.187 0.519 0.2851 1.13 0.782 1.63 -0.00277 0.192 0.989 0.005013 0.997 0.684 1.45 -0.0188 0.193 0.922 0.03523 0.981 0.673 1.43 PRS_PLINK_1e.04 800.3 Fracture of tibia and fibula Both 434 4759 18 injuries & poisonings gray50 4759, 434 1190, 105 1190, 111 1189, 112 1190, 106 0.012 0.0499 0.81 0.09155 1.01 0.918 1.12 0.0545 0.141 0.699 0.1553 1.06 0.801 1.39 0.0826 0.141 0.558 0.2532 1.09 0.824 1.43 0.0233 0.143 0.87 0.06032 1.02 0.774 1.35 PRS_PLINK_1e.04 800.4 Fracture of patella Both 155 1811 18 injuries & poisonings gray50 1811, 155 453, 41 453, 29 452, 43 453, 42 0.0918 0.0817 0.261 0.5832 1.1 0.934 1.29 -0.365 0.248 0.141 0.8493 0.694 0.427 1.13 0.0626 0.227 0.782 0.1067 1.06 0.683 1.66 0.0474 0.227 0.834 0.07862 1.05 0.672 1.64 PRS_PLINK_1e.04 801 Fracture of ankle and foot Both 1046 11934 18 injuries & poisonings gray50 11934, 1046 2983, 264 2983, 257 2983, 270 2984, 255 0.00167 0.0319 0.958 0.01846 1 0.941 1.07 -0.0264 0.0911 0.772 0.1125 0.974 0.815 1.16 0.0237 0.0901 0.793 0.1009 1.02 0.858 1.22 -0.0333 0.0913 0.716 0.1454 0.967 0.809 1.16 PRS_PLINK_1e.04 801.1 Fracture of foot Both 516 5923 18 injuries & poisonings gray50 5923, 516 1480, 120 1481, 133 1480, 131 1481, 132 0.0403 0.0462 0.382 0.4176 1.04 0.951 1.14 0.0946 0.13 0.468 0.3295 1.1 0.851 1.42 0.0878 0.131 0.502 0.299 1.09 0.845 1.41 0.0895 0.131 0.493 0.307 1.09 0.847 1.41 PRS_PLINK_1e.04 802 Fracture of pelvis Both 151 1739 18 injuries & poisonings gray50 1739, 151 435, 35 435, 37 434, 39 435, 40 0.0873 0.0848 0.303 0.5181 1.09 0.924 1.29 0.0892 0.242 0.712 0.1476 1.09 0.681 1.76 0.126 0.238 0.597 0.2241 1.13 0.712 1.81 0.118 0.237 0.619 0.2083 1.13 0.707 1.79 PRS_PLINK_1e.04 803 Fracture of upper limb Both 1036 10502 18 injuries & poisonings gray50 10502, 1036 2626, 267 2625, 247 2625, 272 2626, 250 -0.00743 0.0327 0.82 0.08614 0.993 0.931 1.06 -0.0789 0.0923 0.393 0.4057 0.924 0.771 1.11 0.0195 0.0903 0.829 0.08119 1.02 0.854 1.22 -0.0598 0.0921 0.517 0.2869 0.942 0.786 1.13 PRS_PLINK_1e.04 803.1 Fracture of humerus Both 317 3483 18 injuries & poisonings gray50 3483, 317 871, 84 871, 81 870, 76 871, 76 -0.0426 0.0585 0.466 0.3313 0.958 0.855 1.07 -0.0242 0.163 0.881 0.05478 0.976 0.71 1.34 -0.0725 0.164 0.659 0.1811 0.93 0.674 1.28 -0.0836 0.164 0.61 0.2144 0.92 0.667 1.27 PRS_PLINK_1e.04 803.2 Fracture of radius and ulna Both 591 5868 18 injuries & poisonings gray50 5868, 591 1467, 149 1467, 147 1467, 157 1467, 138 -0.0175 0.0431 0.685 0.1645 0.983 0.903 1.07 -0.00886 0.121 0.942 0.02602 0.991 0.781 1.26 0.0465 0.12 0.698 0.1562 1.05 0.828 1.32 -0.0608 0.123 0.622 0.206 0.941 0.739 1.2 PRS_PLINK_1e.04 803.21 Colles' fracture Both 140 1421 18 injuries & poisonings gray50 1421, 140 356, 36 355, 37 355, 35 355, 32 -0.0393 0.0877 0.654 0.1846 0.961 0.81 1.14 0.0407 0.242 0.867 0.06219 1.04 0.648 1.67 0.00859 0.246 0.972 0.01226 1.01 0.623 1.63 -0.014 0.252 0.956 0.01959 0.986 0.601 1.62 PRS_PLINK_1e.04 803.3 Fracture of clavicle or scapula Both 254 2656 18 injuries & poisonings gray50 2656, 254 663, 61 664, 60 664, 67 664, 66 0.0513 0.0661 0.437 0.3591 1.05 0.925 1.2 -0.0257 0.188 0.891 0.05004 0.975 0.675 1.41 0.0924 0.183 0.615 0.2114 1.1 0.766 1.57 0.1 0.185 0.588 0.2309 1.11 0.77 1.59 PRS_PLINK_1e.04 804 Fracture of hand or wrist Both 874 8647 18 injuries & poisonings gray50 8647, 874 2162, 208 2162, 215 2161, 249 2162, 202 -0.00497 0.0357 0.889 0.05103 0.995 0.928 1.07 0.0289 0.102 0.776 0.1101 1.03 0.843 1.26 0.175 0.0985 0.0757 1.121 1.19 0.982 1.44 -0.0266 0.103 0.797 0.09869 0.974 0.796 1.19 PRS_PLINK_1e.04 805 Fracture of vertebral column without mention of spinal cord injury Both 441 5642 18 injuries & poisonings gray50 5642, 441 1411, 111 1410, 104 1410, 115 1411, 111 0.0356 0.0501 0.477 0.3212 1.04 0.939 1.14 -0.0658 0.14 0.639 0.1944 0.936 0.711 1.23 0.0335 0.137 0.807 0.0929 1.03 0.79 1.35 0.0023 0.138 0.987 0.005806 1 0.764 1.31 PRS_PLINK_1e.04 807 Fracture of ribs Both 240 2887 18 injuries & poisonings gray50 2887, 240 722, 60 722, 62 721, 60 722, 58 -0.0204 0.0687 0.767 0.1154 0.98 0.856 1.12 0.0279 0.186 0.881 0.05506 1.03 0.714 1.48 0.00371 0.188 0.984 0.00691 1 0.695 1.45 -0.0257 0.189 0.892 0.04958 0.975 0.672 1.41 PRS_PLINK_1e.04 809 Fracture of unspecified bones Both 1413 14668 18 injuries & poisonings gray50 14668, 1413 3666, 342 3667, 364 3667, 356 3667, 351 0.0186 0.028 0.506 0.2956 1.02 0.964 1.08 0.0514 0.0789 0.514 0.2888 1.05 0.902 1.23 0.0421 0.0792 0.595 0.2258 1.04 0.893 1.22 0.0286 0.0795 0.719 0.1431 1.03 0.881 1.2 PRS_PLINK_1e.04 816 Cerebral laceration and contusion Both 24 265 18 injuries & poisonings gray50 265, 24 67, 5 66, 10 66, 3 66, 6 0.0146 0.206 0.944 0.02522 1.01 0.678 1.52 0.653 0.529 0.217 0.6639 1.92 0.681 5.42 -0.373 0.636 0.557 0.2542 0.688 0.198 2.39 -0.0913 0.589 0.877 0.05703 0.913 0.288 2.9 PRS_PLINK_1e.04 817 Concussion Both 526 5861 18 injuries & poisonings gray50 5861, 526 1466, 141 1465, 137 1465, 126 1465, 122 -0.0277 0.0457 0.545 0.2638 0.973 0.889 1.06 -0.0354 0.125 0.777 0.1096 0.965 0.756 1.23 -0.105 0.128 0.412 0.3852 0.901 0.701 1.16 -0.136 0.129 0.292 0.5351 0.873 0.679 1.12 PRS_PLINK_1e.04 818 Intracranial hemorrhage (injury) Both 81 1238 18 injuries & poisonings gray50 1238, 81 310, 19 309, 22 309, 25 310, 15 5.66e-05 0.112 1 0.0001753 1 0.803 1.25 0.174 0.313 0.579 0.2375 1.19 0.644 2.2 0.209 0.308 0.497 0.3034 1.23 0.674 2.25 -0.219 0.337 0.516 0.2873 0.804 0.415 1.55 PRS_PLINK_1e.04 818.1 Subdural hemorrhage (injury) Both 19 335 18 injuries & poisonings gray50 335, 19 84, 6 84, 5 83, 5 84, 3 -0.122 0.23 0.597 0.2241 0.886 0.564 1.39 -0.0647 0.552 0.907 0.0425 0.937 0.318 2.77 -0.21 0.579 0.717 0.1442 0.811 0.261 2.52 -0.511 0.626 0.414 0.383 0.6 0.176 2.04 PRS_PLINK_1e.04 818.2 Subarachnoid hemorrhage (injury) Both 34 421 18 injuries & poisonings gray50 421, 34 106, 13 105, 5 105, 12 105, 4 -0.186 0.16 0.245 0.6107 0.83 0.606 1.14 -0.847 0.488 0.0826 1.083 0.429 0.165 1.12 -0.0905 0.408 0.824 0.08384 0.913 0.411 2.03 -1.08 0.52 0.0382 1.418 0.341 0.123 0.943 PRS_PLINK_1e.04 819 Skull and face fracture and other intercranial injury Both 1119 12173 18 injuries & poisonings gray50 12173, 1119 3044, 287 3043, 282 3043, 290 3043, 260 -0.00995 0.0313 0.751 0.1246 0.99 0.931 1.05 -0.0195 0.0875 0.823 0.08438 0.981 0.826 1.16 0.0135 0.087 0.877 0.05714 1.01 0.855 1.2 -0.096 0.0892 0.282 0.5494 0.909 0.763 1.08 PRS_PLINK_1e.04 830 Dislocation Both 2001 17878 18 injuries & poisonings gray50 17878, 2001 4470, 530 4469, 467 4469, 515 4470, 488 -0.00925 0.0236 0.695 0.1578 0.991 0.946 1.04 -0.133 0.0672 0.0478 1.32 0.875 0.767 0.999 -0.0192 0.0657 0.77 0.1137 0.981 0.862 1.12 -0.0688 0.0665 0.301 0.5211 0.934 0.819 1.06 PRS_PLINK_1e.04 835 Internal derangement of knee Both 1172 11457 18 injuries & poisonings gray50 11457, 1172 2865, 302 2864, 268 2864, 308 2864, 294 0.0111 0.0306 0.717 0.1446 1.01 0.952 1.07 -0.129 0.0879 0.142 0.8482 0.879 0.74 1.04 0.0253 0.0851 0.767 0.1154 1.03 0.868 1.21 -0.0217 0.086 0.801 0.09651 0.979 0.827 1.16 PRS_PLINK_1e.04 836 Traumatic arthropathy Both 193 2154 18 injuries & poisonings gray50 2154, 193 539, 59 538, 34 538, 52 539, 48 -0.0432 0.0764 0.572 0.2428 0.958 0.824 1.11 -0.522 0.22 0.0178 1.75 0.593 0.385 0.914 -0.122 0.198 0.538 0.2689 0.885 0.6 1.31 -0.197 0.202 0.329 0.4832 0.821 0.553 1.22 PRS_PLINK_1e.04 840 Sprains and strains Both 3996 18997 18 injuries & poisonings gray50 18997, 3996 4749, 1033 4749, 950 4749, 1021 4749, 992 0.00539 0.0175 0.758 0.1202 1.01 0.971 1.04 -0.0872 0.0498 0.0798 1.098 0.916 0.831 1.01 -0.00157 0.0491 0.975 0.01119 0.998 0.907 1.1 -0.025 0.0494 0.612 0.2132 0.975 0.885 1.07 PRS_PLINK_1e.04 840.1 Muscle/tendon sprain Both 191 2110 18 injuries & poisonings gray50 2110, 191 528, 48 527, 51 527, 45 528, 47 -0.0786 0.0743 0.29 0.5373 0.924 0.799 1.07 0.0485 0.207 0.815 0.0888 1.05 0.699 1.58 -0.0578 0.214 0.787 0.104 0.944 0.621 1.44 -0.0304 0.213 0.887 0.05229 0.97 0.639 1.47 PRS_PLINK_1e.04 840.2 Rotator cuff (capsule) sprain Both 577 6583 18 injuries & poisonings gray50 6583, 577 1646, 155 1646, 141 1645, 140 1646, 141 -0.00903 0.0433 0.835 0.07844 0.991 0.91 1.08 -0.105 0.121 0.386 0.4137 0.9 0.71 1.14 -0.0941 0.121 0.438 0.3589 0.91 0.718 1.15 -0.0997 0.121 0.41 0.3873 0.905 0.714 1.15 PRS_PLINK_1e.04 840.3 Joint/ligament sprain Both 1738 14182 18 injuries & poisonings gray50 14182, 1738 3546, 436 3545, 422 3545, 455 3546, 425 0.00637 0.0256 0.804 0.09496 1.01 0.957 1.06 -0.0389 0.0728 0.593 0.2269 0.962 0.834 1.11 0.0472 0.0716 0.51 0.2927 1.05 0.911 1.21 -0.0112 0.0727 0.877 0.0569 0.989 0.858 1.14 PRS_PLINK_1e.04 841 Sprains and strains of back and neck Both 739 8375 18 injuries & poisonings gray50 8375, 739 2093, 194 2094, 178 2093, 193 2094, 174 -0.0258 0.0383 0.501 0.3005 0.975 0.904 1.05 -0.0863 0.108 0.424 0.3729 0.917 0.742 1.13 -0.000789 0.106 0.994 0.002588 0.999 0.812 1.23 -0.11 0.109 0.312 0.506 0.896 0.724 1.11 PRS_PLINK_1e.04 842 Other sprains and strains Both 696 7539 18 injuries & poisonings gray50 7539, 696 1885, 206 1885, 178 1884, 161 1885, 151 -0.0973 0.0391 0.0129 1.888 0.907 0.84 0.98 -0.149 0.107 0.164 0.7841 0.862 0.698 1.06 -0.246 0.11 0.0253 1.597 0.782 0.631 0.97 -0.308 0.112 0.00574 2.241 0.735 0.59 0.914 PRS_PLINK_1e.04 850 Hemorrhage or hematoma complicating a procedure Both 703 9805 18 injuries & poisonings gray50 9805, 703 2452, 186 2451, 181 2451, 177 2451, 158 -0.0446 0.0386 0.248 0.6051 0.956 0.887 1.03 -0.027 0.108 0.803 0.09552 0.973 0.788 1.2 -0.0577 0.109 0.595 0.2254 0.944 0.763 1.17 -0.157 0.111 0.158 0.8011 0.854 0.687 1.06 PRS_PLINK_1e.04 851 Complications of transplants and reattached limbs Both 767 13385 18 injuries & poisonings gray50 13385, 767 3347, 187 3346, 204 3346, 207 3346, 168 -0.0554 0.0367 0.131 0.8818 0.946 0.88 1.02 0.0838 0.104 0.42 0.3773 1.09 0.887 1.33 0.0992 0.103 0.337 0.4718 1.1 0.902 1.35 -0.121 0.109 0.265 0.5761 0.886 0.716 1.1 PRS_PLINK_1e.04 853 Complication of colostomy or enterostomy Both 169 2174 18 injuries & poisonings gray50 2174, 169 544, 42 543, 42 543, 50 544, 35 -0.071 0.08 0.375 0.4261 0.932 0.796 1.09 -0.000265 0.225 0.999 0.0004096 1 0.644 1.55 0.182 0.217 0.402 0.3958 1.2 0.784 1.83 -0.216 0.233 0.354 0.4511 0.805 0.51 1.27 PRS_PLINK_1e.04 854 Complications of cardiac/vascular device, implant, and graft Both 437 8900 18 injuries & poisonings gray50 8900, 437 2225, 110 2225, 107 2225, 115 2225, 105 -0.0272 0.0487 0.576 0.2396 0.973 0.885 1.07 -0.0372 0.138 0.788 0.1035 0.963 0.735 1.26 0.0382 0.136 0.779 0.1085 1.04 0.796 1.36 -0.0572 0.139 0.681 0.1669 0.944 0.719 1.24 PRS_PLINK_1e.04 855 Complication of nervous system device, implant, and graft Both 114 1379 18 injuries & poisonings gray50 1379, 114 345, 32 345, 29 344, 30 345, 23 -0.142 0.0937 0.129 0.8903 0.867 0.722 1.04 -0.0586 0.262 0.823 0.08455 0.943 0.564 1.58 -0.0608 0.26 0.815 0.08861 0.941 0.565 1.57 -0.353 0.277 0.203 0.6923 0.703 0.408 1.21 PRS_PLINK_1e.04 856 Vascular complications of surgery and medical procedures Both 72 1231 18 injuries & poisonings gray50 1231, 72 308, 16 308, 17 307, 17 308, 22 0.0697 0.12 0.562 0.2504 1.07 0.847 1.36 0.121 0.343 0.724 0.1404 1.13 0.576 2.21 0.0745 0.34 0.827 0.08275 1.08 0.553 2.1 0.306 0.328 0.35 0.4562 1.36 0.715 2.58 PRS_PLINK_1e.04 857 Mechanical complication of unspecified genitourinary device, implant, and graft Both 518 6858 18 injuries & poisonings gray50 6858, 518 1715, 124 1714, 110 1714, 139 1715, 145 0.0737 0.046 0.109 0.963 1.08 0.984 1.18 -0.145 0.135 0.281 0.5508 0.865 0.664 1.13 0.101 0.128 0.428 0.3687 1.11 0.862 1.42 0.15 0.127 0.236 0.6264 1.16 0.906 1.49 PRS_PLINK_1e.04 858 Complication of internal orthopedic device Both 1020 11510 18 injuries & poisonings gray50 11510, 1020 2878, 234 2877, 253 2877, 287 2878, 246 0.0171 0.0327 0.602 0.2202 1.02 0.954 1.08 0.0819 0.0943 0.385 0.4148 1.09 0.902 1.31 0.211 0.0918 0.0217 1.663 1.23 1.03 1.48 0.0488 0.0949 0.607 0.2169 1.05 0.872 1.26 PRS_PLINK_1e.04 859 Complication due to other implant and internal device Both 846 10614 18 injuries & poisonings gray50 10614, 846 2654, 223 2653, 205 2653, 215 2654, 203 -0.0391 0.0354 0.27 0.5689 0.962 0.897 1.03 -0.0843 0.1 0.401 0.3973 0.919 0.755 1.12 -0.0273 0.0991 0.783 0.1064 0.973 0.801 1.18 -0.0893 0.101 0.374 0.4266 0.915 0.751 1.11 PRS_PLINK_1e.04 860 Bone marrow or stem cell transplant Both 43 774 2 neoplasms darkcyan 774, 43 194, 9 193, 12 193, 13 194, 9 -0.0777 0.152 0.61 0.215 0.925 0.687 1.25 0.32 0.421 0.447 0.3494 1.38 0.603 3.15 0.36 0.417 0.388 0.4109 1.43 0.633 3.25 0.0566 0.44 0.898 0.04684 1.06 0.447 2.51 PRS_PLINK_1e.04 870 Open wounds of head; neck; and trunk Both 1610 18355 18 injuries & poisonings gray50 18355, 1610 4588, 411 4589, 416 4588, 395 4589, 388 -0.0314 0.0258 0.224 0.6492 0.969 0.921 1.02 0.0137 0.0725 0.851 0.07027 1.01 0.879 1.17 -0.0383 0.0734 0.602 0.2207 0.962 0.833 1.11 -0.0539 0.0738 0.465 0.3327 0.948 0.82 1.09 PRS_PLINK_1e.04 870.1 Open wound or laceration of eye or eyelid Both 85 914 18 injuries & poisonings gray50 914, 85 229, 15 228, 22 228, 19 229, 29 0.227 0.114 0.0463 1.334 1.25 1 1.57 0.44 0.338 0.193 0.7154 1.55 0.801 3.01 0.219 0.344 0.525 0.28 1.24 0.634 2.44 0.621 0.32 0.0522 1.282 1.86 0.994 3.48 PRS_PLINK_1e.04 870.2 Open wound of ear Both 68 695 18 injuries & poisonings gray50 695, 68 174, 25 174, 15 173, 16 174, 12 -0.2 0.124 0.107 0.9686 0.819 0.642 1.04 -0.53 0.337 0.116 0.9365 0.589 0.304 1.14 -0.439 0.328 0.181 0.7412 0.645 0.339 1.23 -0.631 0.358 0.0779 1.109 0.532 0.264 1.07 PRS_PLINK_1e.04 870.3 Other open wound of head and face Both 582 6206 18 injuries & poisonings gray50 6206, 582 1551, 145 1551, 150 1551, 137 1552, 150 0.000313 0.0432 0.994 0.002513 1 0.919 1.09 0.0378 0.121 0.756 0.1218 1.04 0.819 1.32 -0.0484 0.124 0.696 0.1576 0.953 0.748 1.21 0.0473 0.121 0.697 0.1569 1.05 0.826 1.33 PRS_PLINK_1e.04 870.4 Open wound of nose and sinus Both 84 905 18 injuries & poisonings gray50 905, 84 227, 24 226, 25 226, 14 226, 21 -0.13 0.111 0.241 0.6188 0.878 0.707 1.09 0.0624 0.295 0.832 0.07968 1.06 0.597 1.9 -0.5 0.336 0.137 0.8641 0.606 0.314 1.17 -0.183 0.309 0.555 0.256 0.833 0.455 1.53 PRS_PLINK_1e.04 870.5 Open wound of lip and mouth Both 119 1315 18 injuries & poisonings gray50 1315, 119 329, 28 329, 31 328, 30 329, 30 -0.0932 0.092 0.311 0.5071 0.911 0.761 1.09 0.119 0.266 0.656 0.1832 1.13 0.668 1.9 0.108 0.269 0.688 0.1623 1.11 0.658 1.89 0.0852 0.268 0.75 0.1247 1.09 0.644 1.84 PRS_PLINK_1e.04 870.6 Open wound of neck Both 87 863 18 injuries & poisonings gray50 863, 87 216, 23 216, 24 215, 18 216, 22 -0.0888 0.106 0.402 0.3955 0.915 0.743 1.13 -0.0142 0.305 0.963 0.0165 0.986 0.543 1.79 -0.219 0.325 0.501 0.3001 0.804 0.425 1.52 -0.00209 0.307 0.995 0.002367 0.998 0.547 1.82 PRS_PLINK_1e.04 870.8 Open wound of genital organs Both 80 849 18 injuries & poisonings gray50 849, 80 213, 21 212, 25 212, 17 212, 17 -0.159 0.111 0.152 0.8189 0.853 0.686 1.06 0.18 0.301 0.551 0.2591 1.2 0.663 2.16 -0.163 0.326 0.617 0.2097 0.85 0.448 1.61 -0.211 0.328 0.52 0.2839 0.81 0.426 1.54 PRS_PLINK_1e.04 871 Open wounds of extremities Both 1368 16177 18 injuries & poisonings gray50 16177, 1368 4045, 381 4044, 350 4044, 325 4044, 312 -0.0768 0.0279 0.00581 2.236 0.926 0.877 0.978 -0.0853 0.0772 0.269 0.5703 0.918 0.789 1.07 -0.154 0.0787 0.0509 1.294 0.858 0.735 1 -0.19 0.0795 0.0169 1.773 0.827 0.708 0.966 PRS_PLINK_1e.04 871.1 Open wound of hand except finger(s) Both 261 2886 18 injuries & poisonings gray50 2886, 261 722, 73 721, 71 721, 67 722, 50 -0.111 0.0644 0.0862 1.065 0.895 0.789 1.02 -0.0267 0.173 0.877 0.05679 0.974 0.694 1.37 -0.0813 0.176 0.644 0.1912 0.922 0.653 1.3 -0.369 0.189 0.0513 1.29 0.692 0.478 1 PRS_PLINK_1e.04 871.2 Open wound of finger(s) Both 453 4989 18 injuries & poisonings gray50 4989, 453 1248, 124 1247, 108 1247, 118 1247, 103 -0.088 0.0484 0.0687 1.163 0.916 0.833 1.01 -0.138 0.137 0.311 0.5072 0.871 0.666 1.14 -0.038 0.134 0.776 0.11 0.963 0.741 1.25 -0.179 0.138 0.196 0.7075 0.836 0.638 1.1 PRS_PLINK_1e.04 871.3 Open wound of foot except toe(s) alone Both 126 2127 18 injuries & poisonings gray50 2127, 126 532, 37 532, 31 531, 31 532, 27 -0.159 0.0886 0.0735 1.134 0.853 0.717 1.02 -0.182 0.246 0.459 0.3385 0.833 0.514 1.35 -0.159 0.244 0.514 0.2886 0.853 0.528 1.38 -0.314 0.254 0.217 0.6635 0.731 0.444 1.2 PRS_PLINK_1e.04 871.4 Open wound of toe(s) Both 63 1122 18 injuries & poisonings gray50 1122, 63 281, 13 280, 14 280, 16 281, 20 0.16 0.13 0.221 0.6558 1.17 0.909 1.51 0.166 0.377 0.66 0.1803 1.18 0.564 2.47 0.189 0.37 0.61 0.2148 1.21 0.585 2.49 0.517 0.354 0.144 0.8426 1.68 0.838 3.36 PRS_PLINK_1e.04 872 Traumatic amputation Both 166 2384 18 injuries & poisonings gray50 2384, 166 596, 42 596, 47 596, 36 596, 41 -0.0727 0.0777 0.349 0.4572 0.93 0.799 1.08 0.106 0.217 0.626 0.2031 1.11 0.727 1.7 -0.14 0.23 0.542 0.2657 0.869 0.553 1.36 -0.0174 0.224 0.938 0.02776 0.983 0.633 1.52 PRS_PLINK_1e.04 874 Complication of amputation stump Both 30 736 18 injuries & poisonings gray50 736, 30 184, 12 184, 6 184, 3 184, 9 -0.194 0.184 0.291 0.5358 0.824 0.575 1.18 -0.548 0.47 0.243 0.614 0.578 0.23 1.45 -1.18 0.562 0.0361 1.443 0.308 0.103 0.926 -0.138 0.424 0.744 0.1283 0.871 0.379 2 PRS_PLINK_1e.04 875 Non-healing surgical wound Both 194 2680 18 injuries & poisonings gray50 2680, 194 670, 57 670, 47 670, 45 670, 45 -0.085 0.0735 0.247 0.6067 0.919 0.795 1.06 -0.203 0.202 0.314 0.5027 0.816 0.55 1.21 -0.244 0.204 0.231 0.6372 0.783 0.525 1.17 -0.253 0.204 0.216 0.6658 0.777 0.52 1.16 PRS_PLINK_1e.04 876 Posttraumatic wound infection not elsewhere classified Both 230 3678 18 injuries & poisonings gray50 3678, 230 920, 59 919, 50 919, 47 920, 74 0.0372 0.0673 0.58 0.2364 1.04 0.91 1.18 -0.16 0.195 0.411 0.3865 0.852 0.582 1.25 -0.234 0.198 0.238 0.6233 0.792 0.537 1.17 0.229 0.179 0.202 0.6951 1.26 0.885 1.79 PRS_PLINK_1e.04 907 Injuries to the nervous system Both 474 5022 18 injuries & poisonings gray50 5022, 474 1256, 113 1255, 112 1255, 126 1256, 123 0.0547 0.0482 0.257 0.5904 1.06 0.961 1.16 -0.00251 0.138 0.985 0.006353 0.997 0.761 1.31 0.102 0.135 0.452 0.3449 1.11 0.849 1.44 0.0956 0.136 0.481 0.3179 1.1 0.843 1.44 PRS_PLINK_1e.04 910 Superficial injury, infected Both 40 563 18 injuries & poisonings gray50 563, 40 141, 8 141, 14 140, 9 141, 9 0.0189 0.157 0.904 0.04391 1.02 0.75 1.39 0.592 0.437 0.176 0.7552 1.81 0.767 4.25 0.13 0.46 0.778 0.1089 1.14 0.462 2.8 0.0705 0.465 0.88 0.0557 1.07 0.431 2.67 PRS_PLINK_1e.04 911 Blister Both 61 1174 18 injuries & poisonings gray50 1174, 61 294, 14 293, 19 293, 12 294, 16 -0.0178 0.125 0.886 0.05239 0.982 0.77 1.25 0.269 0.344 0.434 0.3621 1.31 0.667 2.57 -0.0949 0.377 0.801 0.09618 0.909 0.434 1.9 0.0582 0.358 0.871 0.06003 1.06 0.525 2.14 PRS_PLINK_1e.04 912 Insect bite Both 207 2299 18 injuries & poisonings gray50 2299, 207 575, 44 575, 50 574, 55 575, 58 0.0446 0.0721 0.536 0.2709 1.05 0.908 1.2 0.113 0.212 0.595 0.2256 1.12 0.739 1.69 0.255 0.208 0.221 0.6554 1.29 0.858 1.94 0.279 0.205 0.175 0.7571 1.32 0.883 1.98 PRS_PLINK_1e.04 913 Toxic effect of venom Both 157 1544 18 injuries & poisonings gray50 1544, 157 386, 48 386, 38 386, 30 386, 41 -0.0569 0.0835 0.496 0.3046 0.945 0.802 1.11 -0.224 0.226 0.321 0.4936 0.799 0.513 1.24 -0.476 0.24 0.0477 1.322 0.621 0.388 0.995 -0.178 0.223 0.424 0.3722 0.837 0.541 1.3 PRS_PLINK_1e.04 916 Contusion Both 1603 19241 18 injuries & poisonings gray50 19241, 1603 4810, 380 4810, 403 4810, 422 4810, 398 0.0193 0.0261 0.46 0.3371 1.02 0.969 1.07 0.0579 0.0742 0.436 0.361 1.06 0.916 1.23 0.106 0.0735 0.147 0.8312 1.11 0.963 1.28 0.0474 0.0745 0.524 0.2803 1.05 0.906 1.21 PRS_PLINK_1e.04 930 Allergic reaction to food Both 380 4453 18 injuries & poisonings gray50 4453, 380 1114, 100 1113, 90 1113, 97 1113, 93 -0.0531 0.0527 0.314 0.5034 0.948 0.855 1.05 -0.0953 0.15 0.525 0.2799 0.909 0.678 1.22 -0.0234 0.148 0.874 0.05863 0.977 0.732 1.3 -0.0774 0.149 0.604 0.2191 0.926 0.691 1.24 PRS_PLINK_1e.04 931 Contact dermatitis and other eczema due to plants [except food] Both 325 3572 13 dermatologic firebrick 3572, 325 893, 62 893, 87 893, 91 893, 85 0.0984 0.0586 0.0935 1.029 1.1 0.984 1.24 0.355 0.171 0.038 1.421 1.43 1.02 2 0.385 0.17 0.0232 1.634 1.47 1.05 2.05 0.318 0.172 0.064 1.194 1.37 0.982 1.92 PRS_PLINK_1e.04 938 Dermatitis due to solar radiation Both 2152 14191 13 dermatologic firebrick 14191, 2152 3548, 551 3548, 503 3547, 566 3548, 532 -0.018 0.0232 0.438 0.3582 0.982 0.938 1.03 -0.112 0.0669 0.0943 1.025 0.894 0.784 1.02 0.012 0.0651 0.854 0.0686 1.01 0.891 1.15 -0.0474 0.0657 0.471 0.3269 0.954 0.838 1.08 PRS_PLINK_1e.04 938.1 Acute dermatitis due to solar radiation Both 83 1110 13 dermatologic firebrick 1110, 83 278, 20 277, 21 277, 21 278, 21 0.0939 0.113 0.407 0.39 1.1 0.88 1.37 0.142 0.316 0.654 0.1847 1.15 0.62 2.14 0.124 0.316 0.695 0.1578 1.13 0.609 2.1 0.126 0.314 0.689 0.1618 1.13 0.612 2.1 PRS_PLINK_1e.04 938.2 Chronic dermatitis due to solar radiation Both 2040 13822 13 dermatologic firebrick 13822, 2040 3456, 518 3455, 476 3455, 540 3456, 506 -0.0127 0.0238 0.593 0.2273 0.987 0.942 1.03 -0.105 0.0687 0.126 0.9001 0.9 0.787 1.03 0.0247 0.0667 0.711 0.1483 1.03 0.899 1.17 -0.0387 0.0675 0.566 0.2468 0.962 0.843 1.1 PRS_PLINK_1e.04 939 Atopic/contact dermatitis due to other or unspecified Both 2875 17149 13 dermatologic firebrick 17149, 2875 4288, 689 4287, 690 4287, 750 4287, 745 0.0345 0.0205 0.0921 1.036 1.04 0.994 1.08 -0.00933 0.0587 0.874 0.0587 0.991 0.883 1.11 0.0771 0.0578 0.182 0.7392 1.08 0.964 1.21 0.0645 0.0578 0.264 0.578 1.07 0.952 1.19 PRS_PLINK_1e.04 939.1 Contact and allergic dermatitis of eyelid Both 35 429 13 dermatologic firebrick 429, 35 108, 10 107, 11 107, 11 107, 3 -0.221 0.176 0.21 0.6779 0.802 0.568 1.13 0.25 0.45 0.578 0.2381 1.28 0.532 3.1 -0.0211 0.44 0.962 0.0169 0.979 0.413 2.32 -0.979 0.581 0.0919 1.037 0.376 0.12 1.17 PRS_PLINK_1e.04 941 Adverse reaction to serum or vaccine Both 64 902 18 injuries & poisonings gray50 902, 64 226, 23 225, 16 225, 13 226, 12 -0.236 0.118 0.0459 1.338 0.79 0.626 0.996 -0.321 0.327 0.326 0.4862 0.725 0.382 1.38 -0.567 0.351 0.106 0.973 0.567 0.285 1.13 -0.603 0.353 0.0874 1.058 0.547 0.274 1.09 PRS_PLINK_1e.04 942 Infusion and transfusion reaction Both 77 1343 18 injuries & poisonings gray50 1343, 77 336, 17 336, 23 335, 23 336, 14 -0.0563 0.115 0.624 0.2046 0.945 0.754 1.18 0.234 0.315 0.458 0.339 1.26 0.682 2.34 0.314 0.316 0.321 0.4938 1.37 0.736 2.55 -0.218 0.347 0.53 0.2753 0.804 0.407 1.59 PRS_PLINK_1e.04 946 Anaphylactic shock NOS Both 199 2617 18 injuries & poisonings gray50 2617, 199 655, 57 654, 44 654, 58 654, 40 -0.0462 0.0716 0.518 0.2853 0.955 0.83 1.1 -0.255 0.205 0.214 0.6699 0.775 0.519 1.16 0.0228 0.192 0.906 0.043 1.02 0.702 1.49 -0.317 0.21 0.131 0.8829 0.728 0.482 1.1 PRS_PLINK_1e.04 947 Urticaria Both 571 6593 13 dermatologic firebrick 6593, 571 1649, 153 1648, 115 1648, 146 1648, 156 0.00824 0.0433 0.849 0.07109 1.01 0.926 1.1 -0.294 0.128 0.0214 1.669 0.745 0.58 0.957 -0.0458 0.12 0.704 0.1527 0.955 0.755 1.21 0.0171 0.119 0.885 0.05296 1.02 0.806 1.28 PRS_PLINK_1e.04 949 Allergies, other Both 3121 17119 18 injuries & poisonings gray50 17119, 3121 4280, 798 4280, 747 4279, 806 4280, 769 -0.0141 0.0197 0.473 0.3249 0.986 0.949 1.02 -0.0819 0.056 0.144 0.8415 0.921 0.826 1.03 0.00108 0.0552 0.984 0.006805 1 0.898 1.12 -0.055 0.0557 0.324 0.4895 0.947 0.849 1.06 PRS_PLINK_1e.04 952 Spinal cord injury without evidence of spinal bone injury Both 208 2369 18 injuries & poisonings gray50 2369, 208 593, 42 592, 56 592, 50 592, 60 0.18 0.076 0.0177 1.752 1.2 1.03 1.39 0.288 0.209 0.169 0.7733 1.33 0.885 2.01 0.18 0.214 0.401 0.3971 1.2 0.787 1.82 0.388 0.207 0.0609 1.215 1.47 0.982 2.21 PRS_PLINK_1e.04 957 Injury to other and unspecified nerves Both 63 724 18 injuries & poisonings gray50 724, 63 181, 16 181, 19 181, 15 181, 13 -0.0415 0.129 0.747 0.1265 0.959 0.745 1.23 0.194 0.342 0.57 0.2441 1.21 0.621 2.37 -0.116 0.361 0.749 0.1254 0.891 0.439 1.81 -0.154 0.373 0.679 0.1679 0.857 0.413 1.78 PRS_PLINK_1e.04 958 Certain early complications of trauma or procedure Both 436 5668 18 injuries & poisonings gray50 5668, 436 1417, 120 1417, 105 1417, 105 1417, 106 -0.0682 0.0496 0.169 0.771 0.934 0.847 1.03 -0.133 0.138 0.334 0.4761 0.875 0.668 1.15 -0.135 0.138 0.328 0.4837 0.874 0.667 1.15 -0.12 0.138 0.386 0.4136 0.887 0.677 1.16 PRS_PLINK_1e.04 958.1 Postoperative shock Both 35 675 18 injuries & poisonings gray50 675, 35 169, 10 169, 12 168, 7 169, 6 -0.0867 0.159 0.586 0.2322 0.917 0.671 1.25 0.17 0.418 0.684 0.1649 1.19 0.523 2.69 -0.329 0.463 0.478 0.3208 0.72 0.29 1.78 -0.436 0.487 0.37 0.4312 0.647 0.249 1.68 PRS_PLINK_1e.04 958.2 Traumatic and surgical subcutaneous emphysema Both 44 495 18 injuries & poisonings gray50 495, 44 124, 13 124, 11 123, 11 124, 9 -0.157 0.154 0.308 0.5119 0.855 0.633 1.16 -0.111 0.404 0.783 0.1061 0.895 0.405 1.98 -0.135 0.406 0.739 0.1316 0.873 0.394 1.93 -0.35 0.427 0.412 0.3855 0.704 0.305 1.63 PRS_PLINK_1e.04 960 Poisoning by antibiotics Both 841 11097 18 injuries & poisonings gray50 11097, 841 2775, 193 2774, 224 2774, 228 2774, 196 0.0167 0.0359 0.641 0.1932 1.02 0.948 1.09 0.148 0.102 0.144 0.8422 1.16 0.951 1.42 0.167 0.101 0.0996 1.002 1.18 0.969 1.44 0.0132 0.105 0.9 0.04579 1.01 0.825 1.24 PRS_PLINK_1e.04 960.1 Adverse effects of antibacterials (not penicillins) Both 98 1682 18 injuries & poisonings gray50 1682, 98 421, 31 420, 23 420, 24 421, 20 -0.0959 0.106 0.367 0.4349 0.909 0.738 1.12 -0.319 0.275 0.246 0.6084 0.727 0.424 1.25 -0.263 0.273 0.337 0.4729 0.769 0.45 1.31 -0.495 0.285 0.0826 1.083 0.609 0.348 1.07 PRS_PLINK_1e.04 960.2 Allergy/adverse effect of penicillin Both 568 7926 18 injuries & poisonings gray50 7926, 568 1982, 123 1981, 152 1981, 161 1982, 132 0.0304 0.0436 0.486 0.3137 1.03 0.946 1.12 0.216 0.125 0.0833 1.079 1.24 0.972 1.58 0.281 0.123 0.0226 1.646 1.32 1.04 1.69 0.0788 0.128 0.54 0.2679 1.08 0.841 1.39 PRS_PLINK_1e.04 961 Poisoning by other anti-infectives Both 167 2600 18 injuries & poisonings gray50 2600, 167 650, 40 650, 40 650, 47 650, 40 0.0204 0.0788 0.796 0.09921 1.02 0.875 1.19 0.00219 0.226 0.992 0.003364 1 0.643 1.56 0.157 0.218 0.471 0.3267 1.17 0.763 1.79 0.00302 0.226 0.989 0.004657 1 0.644 1.56 PRS_PLINK_1e.04 961.1 Poisoning/allergy of sulfonamides Both 325 4865 18 injuries & poisonings gray50 4865, 325 1217, 96 1216, 72 1216, 77 1216, 80 -0.0742 0.0569 0.192 0.7164 0.928 0.831 1.04 -0.291 0.16 0.069 1.161 0.747 0.546 1.02 -0.2 0.157 0.204 0.6903 0.819 0.602 1.11 -0.171 0.155 0.271 0.567 0.843 0.622 1.14 PRS_PLINK_1e.04 962 Poisoning by hormones and synthetic substitutes Both 183 3784 18 injuries & poisonings gray50 3784, 183 946, 43 946, 43 946, 61 946, 36 0.0172 0.0762 0.821 0.08551 1.02 0.876 1.18 0.00756 0.216 0.972 0.01231 1.01 0.66 1.54 0.331 0.201 0.0987 1.006 1.39 0.94 2.06 -0.185 0.225 0.411 0.3866 0.831 0.534 1.29 PRS_PLINK_1e.04 962.1 Adrenal cortical steroids causing adverse effects in therapeutic use Both 80 1773 18 injuries & poisonings gray50 1773, 80 444, 19 443, 22 443, 23 443, 16 0.00736 0.113 0.948 0.02327 1.01 0.808 1.26 0.206 0.309 0.505 0.2966 1.23 0.67 2.25 0.185 0.307 0.547 0.262 1.2 0.659 2.2 -0.0902 0.332 0.786 0.1045 0.914 0.476 1.75 PRS_PLINK_1e.04 962.2 Insulins and antidiabetic agents causing adverse effects in therapeutic use Both 8 262 18 injuries & poisonings gray50 262, 8 66, 2 65, 0 65, 1 66, 5 0.485 0.317 0.126 0.8999 1.62 0.873 3.02 -1.61 1.23 0.192 0.7171 0.201 0.018 2.24 -0.438 0.849 0.606 0.2174 0.646 0.122 3.41 0.981 0.774 0.205 0.6875 2.67 0.584 12.2 PRS_PLINK_1e.04 962.3 Hormones and synthetic substitutes causing adverse effects in therapeutic use Both 113 2226 18 injuries & poisonings gray50 2226, 113 557, 18 556, 30 556, 43 557, 22 0.11 0.098 0.26 0.5848 1.12 0.922 1.35 0.492 0.291 0.0917 1.038 1.63 0.923 2.89 0.854 0.277 0.00206 2.687 2.35 1.36 4.04 0.173 0.309 0.576 0.2397 1.19 0.648 2.18 PRS_PLINK_1e.04 963 Poisoning by primarily systemic agents Both 1004 12020 18 injuries & poisonings gray50 12020, 1004 3005, 257 3005, 242 3005, 253 3005, 252 -0.0297 0.0328 0.365 0.4379 0.971 0.91 1.04 -0.0601 0.0931 0.519 0.2852 0.942 0.785 1.13 -0.0197 0.0921 0.831 0.0805 0.981 0.819 1.17 -0.0301 0.0923 0.744 0.1283 0.97 0.81 1.16 PRS_PLINK_1e.04 963.1 Antineoplastic and immunosuppressive drugs causing adverse effects Both 984 11796 18 injuries & poisonings gray50 11796, 984 2949, 251 2949, 236 2949, 252 2949, 245 -0.0299 0.0332 0.367 0.4348 0.971 0.91 1.04 -0.0606 0.0942 0.52 0.2839 0.941 0.783 1.13 -0.000215 0.0927 0.998 0.0008026 1 0.834 1.2 -0.0313 0.0934 0.737 0.1323 0.969 0.807 1.16 PRS_PLINK_1e.04 964 Poisoning by agents primarily affecting blood constituents Both 125 2949 18 injuries & poisonings gray50 2949, 125 738, 30 737, 25 737, 34 737, 36 0.029 0.0933 0.756 0.1215 1.03 0.857 1.24 -0.177 0.265 0.504 0.2978 0.837 0.498 1.41 0.0746 0.25 0.765 0.1162 1.08 0.66 1.76 0.146 0.246 0.552 0.258 1.16 0.714 1.88 PRS_PLINK_1e.04 964.1 Anticoagulants causing adverse effects Both 117 2813 18 injuries & poisonings gray50 2813, 117 704, 25 703, 26 703, 31 703, 35 0.0567 0.0966 0.557 0.2539 1.06 0.876 1.28 0.0376 0.274 0.891 0.05014 1.04 0.606 1.78 0.187 0.267 0.483 0.3161 1.21 0.715 2.03 0.307 0.259 0.237 0.6251 1.36 0.817 2.26 PRS_PLINK_1e.04 965 Poisoning by analgesics, antipyretics, and antirheumatics Both 308 4486 18 injuries & poisonings gray50 4486, 308 1122, 74 1121, 88 1121, 69 1122, 77 -0.0188 0.0584 0.748 0.1263 0.981 0.875 1.1 0.192 0.162 0.235 0.6282 1.21 0.882 1.66 -0.0432 0.171 0.8 0.09673 0.958 0.686 1.34 0.0507 0.166 0.76 0.1189 1.05 0.759 1.46 PRS_PLINK_1e.04 965.1 Opiates and related narcotics causing adverse effects in therapeutic use Both 468 7248 18 injuries & poisonings gray50 7248, 468 1812, 126 1812, 124 1812, 114 1812, 103 -0.112 0.0474 0.0178 1.75 0.894 0.815 0.981 0.00146 0.13 0.991 0.003899 1 0.776 1.29 -0.102 0.133 0.442 0.3548 0.903 0.696 1.17 -0.205 0.136 0.133 0.8757 0.815 0.624 1.06 PRS_PLINK_1e.04 965.3 Salicylates causing adverse effects in therapeutic use Both 62 617 18 injuries & poisonings gray50 617, 62 155, 16 154, 16 154, 14 154, 16 0.0208 0.133 0.876 0.0577 1.02 0.787 1.32 -0.027 0.362 0.941 0.02659 0.973 0.479 1.98 -0.163 0.371 0.661 0.18 0.85 0.41 1.76 -0.0152 0.357 0.966 0.01497 0.985 0.489 1.98 PRS_PLINK_1e.04 966 Poisoning by anticonvulsants and anti-Parkinsonism drugs Both 34 512 18 injuries & poisonings gray50 512, 34 128, 16 128, 4 128, 7 128, 7 -0.308 0.162 0.0584 1.233 0.735 0.535 1.01 -1.84 0.616 0.00284 2.547 0.159 0.0475 0.532 -0.807 0.464 0.0822 1.085 0.446 0.18 1.11 -0.796 0.442 0.0714 1.146 0.451 0.19 1.07 PRS_PLINK_1e.04 967 Adverse effects of sedatives or other central nervous system depressants and anesthetics Both 493 6471 18 injuries & poisonings gray50 6471, 493 1618, 135 1618, 121 1617, 129 1618, 108 -0.0648 0.0466 0.164 0.7843 0.937 0.855 1.03 -0.112 0.129 0.387 0.4126 0.894 0.694 1.15 -0.0461 0.127 0.717 0.1444 0.955 0.744 1.23 -0.229 0.133 0.0843 1.074 0.795 0.613 1.03 PRS_PLINK_1e.04 969 Poisoning by psychotropic agents Both 104 1662 18 injuries & poisonings gray50 1662, 104 416, 28 415, 26 415, 20 416, 30 -0.0231 0.102 0.82 0.08604 0.977 0.8 1.19 -0.0896 0.273 0.743 0.1293 0.914 0.536 1.56 -0.367 0.292 0.209 0.679 0.693 0.391 1.23 0.0634 0.264 0.811 0.09115 1.07 0.634 1.79 PRS_PLINK_1e.04 971 Poisoning by drugs primarily affecting the autonomic nervous system Both 16 280 18 injuries & poisonings gray50 280, 16 70, 4 70, 5 70, 4 70, 3 0.123 0.261 0.637 0.1956 1.13 0.678 1.88 0.254 0.608 0.676 0.1703 1.29 0.392 4.24 0.00803 0.646 0.99 0.00433 1.01 0.284 3.58 -0.27 0.695 0.698 0.1562 0.764 0.196 2.98 PRS_PLINK_1e.04 972 Poisoning by agents primarily affecting the cardiovascular system Both 31 1072 18 injuries & poisonings gray50 1072, 31 268, 4 268, 9 268, 6 268, 12 0.185 0.175 0.289 0.5389 1.2 0.855 1.69 0.843 0.526 0.108 0.9646 2.32 0.83 6.51 0.658 0.578 0.255 0.5936 1.93 0.622 5.99 0.981 0.52 0.0592 1.227 2.67 0.963 7.39 PRS_PLINK_1e.04 972.1 Cardiac rhythm regulators causing adverse effects in therapeutic use Both 6 244 18 injuries & poisonings gray50 244, 6 61, 2 61, 0 61, 1 61, 3 0.0445 0.341 0.896 0.04753 1.05 0.535 2.04 -0.0447 1.06 0.966 0.01489 0.956 0.121 7.59 -0.0207 0.897 0.982 0.008061 0.98 0.169 5.68 0.646 0.897 0.471 0.3266 1.91 0.329 11.1 PRS_PLINK_1e.04 972.6 Antihypertensive agents causing adverse effects Both 7 399 18 injuries & poisonings gray50 399, 7 100, 2 100, 4 99, 0 100, 1 -0.499 0.315 0.113 0.9459 0.607 0.327 1.13 0.613 0.692 0.376 0.4249 1.85 0.475 7.16 -0.736 0.99 0.457 0.3398 0.479 0.0689 3.33 0.136 0.893 0.879 0.05582 1.15 0.199 6.59 PRS_PLINK_1e.04 974 Poisoning by water, mineral, and uric acid metabolism drugs Both 9 424 18 injuries & poisonings gray50 424, 9 106, 2 106, 2 106, 1 106, 4 0.173 0.282 0.539 0.2683 1.19 0.684 2.07 0.175 0.745 0.815 0.08905 1.19 0.276 5.13 -0.762 0.925 0.41 0.3874 0.467 0.0762 2.86 0.716 0.71 0.314 0.5037 2.05 0.508 8.24 PRS_PLINK_1e.04 975 Poisoning by agents primarily acting on the smooth and skeletal muscles and respiratory system Both 39 460 18 injuries & poisonings gray50 460, 39 115, 10 115, 7 115, 8 115, 14 0.229 0.167 0.17 0.7684 1.26 0.906 1.75 -0.4 0.481 0.405 0.3923 0.67 0.261 1.72 -0.186 0.458 0.684 0.1649 0.83 0.338 2.04 0.346 0.419 0.408 0.389 1.41 0.622 3.21 PRS_PLINK_1e.04 976 Poisoning by agents primarily affecting skin & mucous membrane, ophthalmological, otorhinolaryngological, & dental drugs Both 21 296 18 injuries & poisonings gray50 296, 21 74, 5 74, 3 74, 9 74, 4 -0.068 0.208 0.744 0.1283 0.934 0.621 1.41 -0.506 0.659 0.442 0.3547 0.603 0.166 2.19 0.348 0.546 0.524 0.281 1.42 0.486 4.13 -0.372 0.623 0.551 0.2589 0.69 0.203 2.34 PRS_PLINK_1e.04 977 Personal history of allergy to medicinal agents Both 484 8167 18 injuries & poisonings gray50 8167, 484 2042, 131 2042, 112 2041, 138 2042, 103 -0.0664 0.0463 0.152 0.819 0.936 0.855 1.02 -0.153 0.132 0.247 0.6079 0.858 0.663 1.11 0.0542 0.125 0.665 0.1772 1.06 0.826 1.35 -0.236 0.134 0.0788 1.104 0.79 0.607 1.03 PRS_PLINK_1e.04 979 Adverse drug events and drug allergies Both 1236 15874 18 injuries & poisonings gray50 15874, 1236 3969, 304 3968, 313 3968, 314 3969, 304 0.00826 0.0296 0.78 0.1076 1.01 0.951 1.07 0.0277 0.0836 0.74 0.1308 1.03 0.873 1.21 0.0311 0.0834 0.709 0.1492 1.03 0.876 1.21 -0.0013 0.084 0.988 0.005377 0.999 0.847 1.18 PRS_PLINK_1e.04 980 Encounter for long-term (current) use of antibiotics Both 480 5721 1 infectious diseases blue 5721, 480 1430, 126 1430, 121 1430, 110 1430, 123 -0.0153 0.0475 0.747 0.1269 0.985 0.897 1.08 -0.0393 0.132 0.766 0.1159 0.961 0.742 1.25 -0.137 0.135 0.312 0.5064 0.872 0.67 1.14 -0.0235 0.131 0.858 0.06653 0.977 0.755 1.26 PRS_PLINK_1e.04 985 Toxic effect of other metals Both 9 211 18 injuries & poisonings gray50 211, 9 53, 3 53, 1 52, 2 53, 3 0.188 0.312 0.546 0.2626 1.21 0.655 2.22 -1.05 0.886 0.234 0.6305 0.348 0.0614 1.98 -0.594 0.768 0.439 0.3574 0.552 0.123 2.49 -0.267 0.805 0.74 0.1308 0.766 0.158 3.71 PRS_PLINK_1e.04 989 Toxic effect of other substances, chiefly nonmedicinal as to source Both 51 586 18 injuries & poisonings gray50 586, 51 147, 19 146, 10 146, 4 147, 18 0.15 0.144 0.297 0.5267 1.16 0.876 1.54 -0.638 0.386 0.0988 1.005 0.529 0.248 1.13 -1.42 0.504 0.00473 2.325 0.241 0.0898 0.647 -0.0353 0.338 0.917 0.0377 0.965 0.498 1.87 PRS_PLINK_1e.04 990 Effects radiation NOS Both 1497 13899 18 injuries & poisonings gray50 13899, 1497 3474, 348 3475, 375 3474, 417 3475, 357 0.00942 0.0272 0.729 0.1373 1.01 0.957 1.06 0.0775 0.0782 0.322 0.4926 1.08 0.927 1.26 0.181 0.0765 0.0178 1.749 1.2 1.03 1.39 0.03 0.079 0.704 0.1524 1.03 0.883 1.2 PRS_PLINK_1e.04 994 Sepsis and SIRS Both 509 9238 18 injuries & poisonings gray50 9238, 509 2310, 118 2309, 136 2309, 130 2310, 125 0.0251 0.0461 0.586 0.2319 1.03 0.937 1.12 0.14 0.128 0.275 0.561 1.15 0.895 1.48 0.0954 0.13 0.462 0.3353 1.1 0.853 1.42 0.0517 0.131 0.693 0.1592 1.05 0.815 1.36 PRS_PLINK_1e.04 994.1 Systemic inflammatory response syndrome (SIRS) Both 79 1372 18 injuries & poisonings gray50 1372, 79 343, 21 343, 18 343, 20 343, 20 -0.13 0.113 0.252 0.5989 0.879 0.704 1.1 -0.234 0.32 0.465 0.3322 0.792 0.423 1.48 -0.0529 0.311 0.865 0.06302 0.948 0.515 1.75 -0.0832 0.31 0.789 0.1032 0.92 0.501 1.69 PRS_PLINK_1e.04 994.2 Sepsis Both 469 8715 18 injuries & poisonings gray50 8715, 469 2179, 105 2179, 129 2178, 120 2179, 115 0.0521 0.0481 0.279 0.5544 1.05 0.959 1.16 0.206 0.134 0.124 0.9074 1.23 0.945 1.6 0.134 0.136 0.326 0.4874 1.14 0.876 1.49 0.0903 0.137 0.511 0.2914 1.09 0.836 1.43 PRS_PLINK_1e.04 994.21 Septic shock Both 111 2535 18 injuries & poisonings gray50 2535, 111 634, 33 634, 25 633, 27 634, 26 -0.0371 0.096 0.699 0.1554 0.964 0.798 1.16 -0.274 0.263 0.297 0.5269 0.76 0.454 1.27 -0.173 0.258 0.501 0.3003 0.841 0.507 1.39 -0.256 0.261 0.326 0.4874 0.774 0.464 1.29 PRS_PLINK_1e.04