phewas_code phewas_string sex MatchedCases MatchedControls groupnum group color N N_Q1 N_Q2 N_Q3 N_Q4 PRS_BETA PRS_SEBETA PRS_P PRS_LOG10P PRS_OR PRS_CI1 PRS_CI2 Q1Q2_BETA Q1Q2_SEBETA Q1Q2_P Q1Q2_LOG10P Q1Q2_OR Q1Q2_CI1 Q1Q2_CI2 Q1Q3_BETA Q1Q3_SEBETA Q1Q3_P Q1Q3_LOG10P Q1Q3_OR Q1Q3_CI1 Q1Q3_CI2 Q1Q4_BETA Q1Q4_SEBETA Q1Q4_P Q1Q4_LOG10P Q1Q4_OR Q1Q4_CI1 Q1Q4_CI2 predictor exclude 008 Intestinal infection Both 946 8151 1 infectious diseases blue 8151, 946 2038, 203 2038, 247 2037, 240 2038, 255 0.0972 0.0355 0.00622 2.206 1.1 1.03 1.18 0.204 0.1 0.0415 1.382 1.23 1.01 1.49 0.182 0.102 0.0737 1.132 1.2 0.983 1.47 0.212 0.104 0.0413 1.384 1.24 1.01 1.52 PRS_PLINK_0.0199526231496888 FALSE 008.5 Bacterial enteritis Both 417 3348 1 infectious diseases blue 3348, 417 837, 87 837, 108 837, 112 837, 110 0.139 0.0535 0.0092 2.036 1.15 1.04 1.28 0.218 0.152 0.152 0.8173 1.24 0.923 1.68 0.267 0.153 0.0818 1.087 1.31 0.967 1.76 0.226 0.16 0.157 0.8029 1.25 0.917 1.71 PRS_PLINK_0.0199526231496888 FALSE 008.52 Intestinal infection due to C. difficile Both 333 2590 1 infectious diseases blue 2590, 333 648, 65 647, 87 647, 92 648, 89 0.167 0.0596 0.00516 2.288 1.18 1.05 1.33 0.32 0.174 0.0648 1.188 1.38 0.981 1.94 0.371 0.175 0.0335 1.475 1.45 1.03 2.04 0.292 0.181 0.107 0.969 1.34 0.938 1.91 PRS_PLINK_0.0199526231496888 FALSE 008.6 Viral Enteritis Both 254 2299 1 infectious diseases blue 2299, 254 575, 62 575, 63 574, 61 575, 67 0.0388 0.0675 0.565 0.2476 1.04 0.911 1.19 -0.00158 0.187 0.993 0.002945 0.998 0.692 1.44 0.000635 0.191 0.997 0.001156 1 0.689 1.45 0.0328 0.194 0.866 0.06252 1.03 0.706 1.51 PRS_PLINK_0.0199526231496888 FALSE 010 Tuberculosis Both 72 579 1 infectious diseases blue 579, 72 145, 13 145, 20 144, 14 145, 25 0.186 0.131 0.155 0.809 1.2 0.932 1.56 0.523 0.375 0.163 0.7891 1.69 0.81 3.52 0.338 0.407 0.406 0.3912 1.4 0.631 3.11 0.701 0.384 0.0674 1.171 2.02 0.951 4.28 PRS_PLINK_0.0199526231496888 FALSE 031 Diseases due to other mycobacteria Both 36 211 1 infectious diseases blue 211, 36 53, 5 53, 5 52, 14 53, 12 0.448 0.188 0.017 1.769 1.57 1.08 2.26 0.189 0.642 0.768 0.1144 1.21 0.343 4.25 1.24 0.594 0.0374 1.428 3.44 1.07 11 1.19 0.619 0.0534 1.272 3.3 0.983 11.1 PRS_PLINK_0.0199526231496888 TRUE 038 Septicemia Both 859 5489 1 infectious diseases blue 5489, 859 1373, 188 1372, 210 1372, 212 1372, 248 0.127 0.0375 0.000716 3.145 1.14 1.05 1.22 0.132 0.108 0.221 0.6559 1.14 0.924 1.41 0.124 0.109 0.257 0.5899 1.13 0.914 1.4 0.277 0.108 0.0104 1.981 1.32 1.07 1.63 PRS_PLINK_0.0199526231496888 FALSE 038.1 Gram negative septicemia Both 181 1149 1 infectious diseases blue 1149, 181 288, 32 287, 56 287, 45 287, 48 0.127 0.0838 0.128 0.8916 1.14 0.964 1.34 0.573 0.235 0.0148 1.831 1.77 1.12 2.81 0.288 0.246 0.241 0.6172 1.33 0.824 2.16 0.38 0.252 0.131 0.8818 1.46 0.893 2.4 PRS_PLINK_0.0199526231496888 FALSE 038.2 Gram positive septicemia Both 84 492 1 infectious diseases blue 492, 84 123, 17 123, 18 123, 22 123, 27 0.196 0.121 0.105 0.9776 1.22 0.96 1.54 0.0558 0.365 0.879 0.05624 1.06 0.517 2.16 0.381 0.361 0.291 0.5355 1.46 0.721 2.97 0.504 0.352 0.152 0.8185 1.65 0.831 3.3 PRS_PLINK_0.0199526231496888 FALSE 038.3 Bacteremia Both 379 2492 1 infectious diseases blue 2492, 379 623, 72 623, 103 623, 91 623, 112 0.167 0.0565 0.00318 2.497 1.18 1.06 1.32 0.37 0.164 0.024 1.62 1.45 1.05 2 0.258 0.171 0.131 0.8835 1.29 0.926 1.81 0.438 0.168 0.00912 2.04 1.55 1.11 2.15 PRS_PLINK_0.0199526231496888 FALSE 041 Bacterial infection NOS Both 1829 10344 1 infectious diseases blue 10344, 1829 2586, 438 2586, 439 2586, 437 2586, 514 0.0894 0.0262 0.000641 3.193 1.09 1.04 1.15 0.0171 0.0736 0.816 0.08836 1.02 0.881 1.18 0.00686 0.0746 0.927 0.03303 1.01 0.87 1.17 0.18 0.0742 0.0151 1.822 1.2 1.04 1.39 PRS_PLINK_0.0199526231496888 FALSE 041.1 Staphylococcus infections Both 513 4030 1 infectious diseases blue 4030, 513 1008, 132 1007, 103 1007, 131 1008, 147 0.0885 0.0478 0.064 1.194 1.09 0.995 1.2 -0.239 0.139 0.0863 1.064 0.787 0.599 1.03 0.0024 0.133 0.986 0.006302 1 0.772 1.3 0.117 0.133 0.378 0.423 1.12 0.867 1.46 PRS_PLINK_0.0199526231496888 FALSE 041.11 Methicillin sensitive Staphylococcus aureus Both 292 2120 1 infectious diseases blue 2120, 292 530, 69 530, 62 530, 68 530, 93 0.136 0.0629 0.0313 1.505 1.15 1.01 1.3 -0.0411 0.188 0.827 0.0826 0.96 0.664 1.39 -0.0166 0.183 0.928 0.03241 0.984 0.687 1.41 0.311 0.177 0.079 1.103 1.37 0.965 1.93 PRS_PLINK_0.0199526231496888 FALSE 041.12 Methicillin resistant Staphylococcus aureus Both 229 1868 1 infectious diseases blue 1868, 229 467, 50 467, 46 467, 61 467, 72 0.157 0.0694 0.0233 1.632 1.17 1.02 1.34 -0.1 0.213 0.639 0.1946 0.905 0.596 1.37 0.189 0.202 0.349 0.4568 1.21 0.813 1.8 0.314 0.2 0.116 0.9365 1.37 0.926 2.02 PRS_PLINK_0.0199526231496888 FALSE 041.2 Streptococcus infection Both 497 3806 1 infectious diseases blue 3806, 497 952, 127 951, 115 951, 113 952, 141 0.0711 0.0483 0.141 0.8497 1.07 0.977 1.18 -0.113 0.137 0.412 0.3852 0.894 0.683 1.17 -0.16 0.14 0.252 0.599 0.852 0.648 1.12 0.121 0.137 0.379 0.4211 1.13 0.862 1.48 PRS_PLINK_0.0199526231496888 FALSE 041.21 Rheumatic fever / chorea Both 49 583 1 infectious diseases blue 583, 49 146, 14 146, 13 145, 10 146, 12 -0.00521 0.144 0.971 0.01273 0.995 0.75 1.32 0.00489 0.388 0.99 0.004382 1 0.469 2.15 -0.349 0.43 0.417 0.3797 0.706 0.304 1.64 -0.118 0.414 0.777 0.1098 0.889 0.395 2 PRS_PLINK_0.0199526231496888 TRUE 041.4 E. coli Both 361 2752 1 infectious diseases blue 2752, 361 688, 79 688, 101 688, 78 688, 103 0.107 0.0576 0.0636 1.196 1.11 0.994 1.25 0.264 0.159 0.0982 1.008 1.3 0.952 1.78 0.0144 0.171 0.933 0.03032 1.01 0.726 1.42 0.257 0.166 0.123 0.9092 1.29 0.933 1.79 PRS_PLINK_0.0199526231496888 FALSE 041.8 H. pylori Both 76 686 1 infectious diseases blue 686, 76 172, 14 171, 25 171, 22 172, 15 0.0266 0.12 0.824 0.08388 1.03 0.812 1.3 0.687 0.352 0.0511 1.292 1.99 0.997 3.96 0.536 0.362 0.139 0.8555 1.71 0.84 3.48 -0.0969 0.413 0.814 0.08915 0.908 0.404 2.04 PRS_PLINK_0.0199526231496888 FALSE 041.9 Infection with drug-resistant microorganisms Both 118 868 1 infectious diseases blue 868, 118 217, 23 217, 31 217, 27 217, 36 0.202 0.1 0.0437 1.359 1.22 1.01 1.49 0.339 0.29 0.241 0.6176 1.4 0.796 2.48 0.0999 0.308 0.746 0.1275 1.11 0.604 2.02 0.561 0.297 0.0586 1.232 1.75 0.98 3.14 PRS_PLINK_0.0199526231496888 FALSE 053 Herpes zoster Both 389 3645 1 infectious diseases blue 3645, 389 912, 102 911, 93 911, 91 911, 103 -0.0546 0.0559 0.328 0.4839 0.947 0.849 1.06 -0.12 0.151 0.427 0.3697 0.887 0.659 1.19 -0.18 0.154 0.242 0.6154 0.835 0.618 1.13 -0.0799 0.155 0.605 0.2182 0.923 0.682 1.25 PRS_PLINK_0.0199526231496888 FALSE 053.1 Herpes zoster with nervous system complications Both 47 490 1 infectious diseases blue 490, 47 123, 12 122, 10 122, 12 123, 13 0.0033 0.155 0.983 0.007456 1 0.741 1.36 -0.268 0.428 0.531 0.2747 0.765 0.331 1.77 -0.149 0.426 0.726 0.139 0.861 0.374 1.98 0.024 0.422 0.955 0.02021 1.02 0.448 2.34 PRS_PLINK_0.0199526231496888 TRUE 054 Herpes simplex Both 573 4848 1 infectious diseases blue 4848, 573 1212, 165 1212, 135 1212, 144 1212, 129 -0.0781 0.0458 0.0882 1.055 0.925 0.845 1.01 -0.206 0.123 0.0949 1.023 0.814 0.639 1.04 -0.157 0.123 0.202 0.6945 0.855 0.672 1.09 -0.309 0.129 0.0166 1.779 0.734 0.57 0.945 PRS_PLINK_0.0199526231496888 FALSE 070 Viral hepatitis Both 216 1915 1 infectious diseases blue 1915, 216 479, 48 479, 47 478, 61 479, 60 0.108 0.0719 0.132 0.878 1.11 0.968 1.28 -0.0548 0.215 0.799 0.09772 0.947 0.622 1.44 0.285 0.207 0.169 0.7731 1.33 0.886 2 0.171 0.213 0.423 0.3741 1.19 0.781 1.8 PRS_PLINK_0.0199526231496888 FALSE 070.1 Viral hepatitis A Both 17 173 1 infectious diseases blue 173, 17 44, 4 43, 5 43, 6 43, 2 0.0552 0.258 0.83 0.08071 1.06 0.637 1.75 0.303 0.665 0.649 0.1879 1.35 0.368 4.98 0.537 0.75 0.474 0.3241 1.71 0.393 7.44 -0.0798 0.882 0.928 0.03247 0.923 0.164 5.2 PRS_PLINK_0.0199526231496888 TRUE 070.2 Viral hepatitis B Both 66 491 1 infectious diseases blue 491, 66 123, 14 123, 10 122, 24 123, 18 0.027 0.134 0.84 0.07587 1.03 0.791 1.34 -0.404 0.424 0.34 0.4683 0.668 0.291 1.53 0.354 0.372 0.341 0.4674 1.42 0.688 2.95 -0.0233 0.405 0.954 0.02043 0.977 0.442 2.16 PRS_PLINK_0.0199526231496888 FALSE 070.3 Viral hepatitis C Both 133 1196 1 infectious diseases blue 1196, 133 299, 28 299, 28 299, 37 299, 40 0.194 0.0921 0.0349 1.457 1.21 1.01 1.45 0.0136 0.275 0.96 0.01757 1.01 0.592 1.74 0.366 0.268 0.172 0.7654 1.44 0.853 2.44 0.27 0.27 0.316 0.5003 1.31 0.773 2.22 PRS_PLINK_0.0199526231496888 FALSE 070.4 Chronic hepatitis Both 56 459 1 infectious diseases blue 459, 56 115, 13 115, 11 114, 17 115, 15 0.0947 0.142 0.506 0.2959 1.1 0.832 1.45 -0.0658 0.431 0.879 0.05611 0.936 0.402 2.18 0.37 0.404 0.36 0.4439 1.45 0.656 3.19 0.314 0.428 0.462 0.3352 1.37 0.592 3.17 PRS_PLINK_0.0199526231496888 FALSE 070.9 Hepatitis NOS Both 264 2528 1 infectious diseases blue 2528, 264 632, 66 632, 50 632, 76 632, 72 0.0759 0.0654 0.246 0.6099 1.08 0.949 1.23 -0.27 0.195 0.165 0.7814 0.763 0.521 1.12 0.163 0.18 0.364 0.4392 1.18 0.828 1.67 0.161 0.186 0.385 0.4147 1.18 0.817 1.69 PRS_PLINK_0.0199526231496888 FALSE 071 Human immunodeficiency virus [HIV] disease Both 38 368 1 infectious diseases blue 368, 38 92, 9 92, 4 92, 7 92, 18 0.214 0.165 0.193 0.7135 1.24 0.897 1.71 -0.774 0.572 0.176 0.7544 0.461 0.15 1.42 -0.326 0.5 0.515 0.2885 0.722 0.271 1.92 0.631 0.463 0.173 0.7614 1.88 0.758 4.66 PRS_PLINK_0.0199526231496888 TRUE 071.1 HIV infection, symptomatic Both 32 269 1 infectious diseases blue 269, 32 68, 8 67, 3 67, 6 67, 15 0.289 0.188 0.124 0.908 1.34 0.924 1.93 -0.784 0.602 0.193 0.7152 0.457 0.14 1.49 -0.347 0.543 0.523 0.2814 0.707 0.244 2.05 0.744 0.492 0.131 0.8833 2.1 0.802 5.52 PRS_PLINK_0.0199526231496888 TRUE 078 Viral warts & HPV Both 1104 8387 1 infectious diseases blue 8387, 1104 2097, 324 2097, 269 2096, 251 2097, 259 -0.0694 0.0333 0.037 1.431 0.933 0.874 0.996 -0.19 0.0889 0.0328 1.484 0.827 0.695 0.985 -0.285 0.0917 0.00184 2.734 0.752 0.628 0.9 -0.252 0.0932 0.00673 2.172 0.777 0.647 0.933 PRS_PLINK_0.0199526231496888 FALSE 079 Viral infection Both 2022 9425 1 infectious diseases blue 9425, 2022 2357, 508 2356, 501 2356, 500 2356, 513 -0.00378 0.0255 0.882 0.05452 0.996 0.948 1.05 -0.0149 0.0704 0.832 0.07962 0.985 0.858 1.13 -0.025 0.0712 0.725 0.1396 0.975 0.848 1.12 -0.0247 0.0731 0.735 0.1337 0.976 0.845 1.13 PRS_PLINK_0.0199526231496888 FALSE 079.1 Varicella infection Both 1041 8455 1 infectious diseases blue 8455, 1041 2114, 266 2114, 258 2113, 269 2114, 248 -0.035 0.034 0.302 0.5197 0.966 0.903 1.03 -0.0194 0.0935 0.836 0.07804 0.981 0.817 1.18 0.028 0.0938 0.765 0.1164 1.03 0.856 1.24 -0.0654 0.0985 0.507 0.2953 0.937 0.772 1.14 PRS_PLINK_0.0199526231496888 FALSE 079.2 Infectious mononucleosis Both 101 976 1 infectious diseases blue 976, 101 244, 32 244, 21 244, 16 244, 32 0.00547 0.105 0.959 0.01836 1.01 0.818 1.24 -0.418 0.294 0.154 0.8118 0.658 0.37 1.17 -0.609 0.321 0.058 1.236 0.544 0.29 1.02 0.0551 0.28 0.844 0.07356 1.06 0.61 1.83 PRS_PLINK_0.0199526231496888 FALSE 079.9 Viremia, NOS Both 248 2464 1 infectious diseases blue 2464, 248 616, 64 616, 62 616, 62 616, 60 0.000372 0.0693 0.996 0.001862 1 0.873 1.15 -0.0522 0.187 0.78 0.1078 0.949 0.658 1.37 -0.0347 0.189 0.855 0.06813 0.966 0.666 1.4 -0.0373 0.196 0.849 0.07111 0.963 0.656 1.41 PRS_PLINK_0.0199526231496888 FALSE 080 Postoperative infection Both 798 6866 1 infectious diseases blue 6866, 798 1717, 183 1716, 200 1716, 211 1717, 203 0.0535 0.0384 0.163 0.7872 1.05 0.979 1.14 0.0962 0.108 0.374 0.4276 1.1 0.891 1.36 0.139 0.108 0.199 0.7017 1.15 0.93 1.42 0.121 0.112 0.28 0.5522 1.13 0.906 1.41 PRS_PLINK_0.0199526231496888 FALSE 081 Infection/inflammation of internal prosthetic device; implant; and graft Both 503 3937 1 infectious diseases blue 3937, 503 985, 109 984, 125 984, 129 984, 139 0.116 0.0486 0.0167 1.777 1.12 1.02 1.24 0.15 0.139 0.28 0.5533 1.16 0.885 1.52 0.142 0.139 0.309 0.5105 1.15 0.877 1.51 0.261 0.141 0.0635 1.197 1.3 0.985 1.71 PRS_PLINK_0.0199526231496888 FALSE 090 Sexually transmitted infections (not HIV or hepatitis) Both 345 3263 1 infectious diseases blue 3263, 345 816, 78 816, 97 815, 87 816, 83 0.0362 0.0585 0.536 0.2706 1.04 0.925 1.16 0.209 0.159 0.19 0.721 1.23 0.902 1.68 0.083 0.165 0.615 0.2109 1.09 0.786 1.5 0.0368 0.173 0.831 0.08047 1.04 0.74 1.45 PRS_PLINK_0.0199526231496888 FALSE 110 Dermatophytosis / Dermatomycosis Both 831 7508 1 infectious diseases blue 7508, 831 1877, 234 1877, 211 1877, 181 1877, 205 -0.0447 0.0381 0.241 0.6182 0.956 0.887 1.03 -0.115 0.102 0.259 0.5874 0.891 0.73 1.09 -0.259 0.107 0.016 1.797 0.772 0.626 0.953 -0.13 0.107 0.227 0.6443 0.878 0.712 1.08 PRS_PLINK_0.0199526231496888 FALSE 110.1 Dermatophytosis Both 736 6632 1 infectious diseases blue 6632, 736 1658, 201 1658, 191 1658, 161 1658, 183 -0.0326 0.0407 0.422 0.3746 0.968 0.894 1.05 -0.0659 0.108 0.543 0.2653 0.936 0.757 1.16 -0.224 0.114 0.0508 1.294 0.8 0.639 1 -0.0733 0.115 0.523 0.2815 0.929 0.742 1.16 PRS_PLINK_0.0199526231496888 FALSE 110.11 Dermatophytosis of nail Both 437 3789 1 infectious diseases blue 3789, 437 948, 114 947, 119 947, 103 947, 101 -0.0187 0.0524 0.722 0.1417 0.981 0.886 1.09 0.0388 0.141 0.783 0.1064 1.04 0.789 1.37 -0.0988 0.147 0.501 0.3006 0.906 0.68 1.21 -0.116 0.153 0.447 0.3495 0.89 0.659 1.2 PRS_PLINK_0.0199526231496888 FALSE 110.12 Althete's foot Both 174 1776 1 infectious diseases blue 1776, 174 444, 42 444, 42 444, 40 444, 50 0.0506 0.0799 0.526 0.2788 1.05 0.899 1.23 0.0401 0.227 0.86 0.06559 1.04 0.667 1.62 -0.0624 0.238 0.793 0.1006 0.94 0.589 1.5 0.277 0.231 0.231 0.6372 1.32 0.839 2.07 PRS_PLINK_0.0199526231496888 FALSE 110.13 Dermatophytosis of the body Both 201 2011 1 infectious diseases blue 2011, 201 503, 55 503, 54 502, 49 503, 43 -0.0961 0.0771 0.213 0.6724 0.908 0.781 1.06 -0.0582 0.202 0.773 0.112 0.943 0.636 1.4 -0.0957 0.208 0.646 0.1897 0.909 0.604 1.37 -0.285 0.222 0.199 0.7021 0.752 0.487 1.16 PRS_PLINK_0.0199526231496888 FALSE 110.2 Dermatomycoses Both 119 1190 1 infectious diseases blue 1190, 119 298, 44 297, 29 297, 19 298, 27 -0.168 0.0975 0.0843 1.074 0.845 0.698 1.02 -0.38 0.249 0.126 0.898 0.684 0.42 1.11 -0.776 0.284 0.00628 2.202 0.46 0.264 0.803 -0.399 0.264 0.132 0.8808 0.671 0.4 1.13 PRS_PLINK_0.0199526231496888 FALSE 112 Candidiasis Both 1270 8911 1 infectious diseases blue 8911, 1270 2228, 333 2228, 302 2227, 302 2228, 332 -0.00312 0.031 0.92 0.03628 0.997 0.938 1.06 -0.103 0.0852 0.228 0.6416 0.902 0.764 1.07 -0.114 0.0866 0.187 0.7277 0.892 0.753 1.06 -0.0122 0.0871 0.889 0.05126 0.988 0.833 1.17 PRS_PLINK_0.0199526231496888 FALSE 112.3 Candidiasis of skin and nails Both 156 1829 1 infectious diseases blue 1829, 156 458, 52 457, 22 457, 36 457, 46 -0.0434 0.0861 0.614 0.212 0.957 0.809 1.13 -0.843 0.259 0.00111 2.955 0.43 0.259 0.714 -0.316 0.229 0.167 0.7779 0.729 0.465 1.14 -0.0304 0.222 0.891 0.04989 0.97 0.627 1.5 PRS_PLINK_0.0199526231496888 FALSE 117 Mycoses Both 203 1613 1 infectious diseases blue 1613, 203 404, 47 403, 38 403, 58 403, 60 0.133 0.0761 0.0809 1.092 1.14 0.984 1.33 -0.216 0.228 0.344 0.4634 0.806 0.515 1.26 0.207 0.21 0.324 0.489 1.23 0.815 1.86 0.275 0.214 0.2 0.6999 1.32 0.865 2 PRS_PLINK_0.0199526231496888 FALSE 117.1 Histoplasmosis Both 21 187 1 infectious diseases blue 187, 21 47, 2 47, 6 46, 11 47, 2 -0.058 0.254 0.819 0.08648 0.944 0.573 1.55 1.18 0.819 0.151 0.8204 3.24 0.651 16.1 1.37 0.705 0.052 1.284 3.93 0.988 15.7 0.366 0.86 0.671 0.1733 1.44 0.267 7.78 PRS_PLINK_0.0199526231496888 TRUE 117.4 Aspergillosis Both 42 358 1 infectious diseases blue 358, 42 90, 9 89, 18 89, 8 90, 7 -0.0695 0.177 0.694 0.1587 0.933 0.66 1.32 0.684 0.422 0.105 0.979 1.98 0.867 4.53 -0.301 0.487 0.537 0.2703 0.74 0.285 1.92 0.0215 0.534 0.968 0.01418 1.02 0.358 2.91 PRS_PLINK_0.0199526231496888 TRUE 130 Spirochetal infection Both 63 441 1 infectious diseases blue 441, 63 111, 19 110, 9 110, 18 110, 17 0.0517 0.136 0.703 0.1528 1.05 0.807 1.37 -0.648 0.421 0.124 0.9053 0.523 0.229 1.2 0.101 0.359 0.778 0.1091 1.11 0.548 2.23 -0.0233 0.37 0.95 0.02235 0.977 0.473 2.02 PRS_PLINK_0.0199526231496888 FALSE 130.1 Lyme disease Both 43 323 1 infectious diseases blue 323, 43 81, 15 81, 6 80, 14 81, 8 -0.0456 0.168 0.786 0.1045 0.955 0.687 1.33 -0.815 0.485 0.0929 1.032 0.443 0.171 1.15 0.193 0.424 0.649 0.1879 1.21 0.528 2.79 -0.422 0.46 0.359 0.4448 0.656 0.266 1.62 PRS_PLINK_0.0199526231496888 TRUE 131 Protozoan infection Both 30 260 1 infectious diseases blue 260, 30 65, 7 65, 6 65, 4 65, 13 0.224 0.197 0.254 0.5959 1.25 0.851 1.84 -0.288 0.57 0.613 0.2128 0.749 0.245 2.29 -0.504 0.609 0.407 0.39 0.604 0.183 1.99 0.42 0.515 0.415 0.3815 1.52 0.554 4.18 PRS_PLINK_0.0199526231496888 TRUE 132 Infestation (lice, mites) Both 64 588 1 infectious diseases blue 588, 64 147, 18 147, 12 147, 12 147, 22 0.0868 0.129 0.5 0.3014 1.09 0.848 1.4 -0.352 0.374 0.347 0.4593 0.703 0.338 1.47 -0.291 0.38 0.444 0.3531 0.747 0.355 1.57 0.207 0.348 0.552 0.2584 1.23 0.622 2.44 PRS_PLINK_0.0199526231496888 FALSE 134 Helminthiases Both 31 216 1 infectious diseases blue 216, 31 54, 13 54, 7 54, 5 54, 6 -0.286 0.197 0.147 0.8318 0.751 0.51 1.11 -0.411 0.507 0.418 0.3791 0.663 0.245 1.79 -0.817 0.581 0.16 0.7958 0.442 0.141 1.38 -0.666 0.591 0.259 0.5859 0.514 0.161 1.64 PRS_PLINK_0.0199526231496888 TRUE 134.1 Intestinal helminthiases Both 21 145 1 infectious diseases blue 145, 21 37, 10 36, 3 36, 3 36, 5 -0.287 0.23 0.213 0.6718 0.751 0.478 1.18 -1.1 0.649 0.0899 1.046 0.332 0.0931 1.19 -0.75 0.707 0.289 0.5396 0.472 0.118 1.89 -0.538 0.616 0.382 0.4176 0.584 0.175 1.95 PRS_PLINK_0.0199526231496888 TRUE 136 Other infectious and parasitic diseases Both 1009 8983 1 infectious diseases blue 8983, 1009 2246, 253 2246, 266 2245, 249 2246, 240 0.0102 0.0344 0.768 0.1147 1.01 0.944 1.08 0.0589 0.0933 0.528 0.2776 1.06 0.883 1.27 0.02 0.096 0.835 0.07811 1.02 0.845 1.23 -0.0486 0.0999 0.626 0.2031 0.953 0.783 1.16 PRS_PLINK_0.0199526231496888 FALSE 145 Cancer of mouth Both 275 3038 2 neoplasms darkcyan 3038, 275 759, 79 759, 62 759, 75 760, 59 -0.11 0.0632 0.0814 1.09 0.896 0.791 1.01 -0.246 0.176 0.162 0.7904 0.782 0.554 1.1 -0.0699 0.17 0.682 0.1665 0.933 0.668 1.3 -0.295 0.185 0.111 0.9565 0.745 0.518 1.07 PRS_PLINK_0.0199526231496888 FALSE 145.1 Cancer of lip Both 12 140 2 neoplasms darkcyan 140, 12 35, 3 35, 5 35, 2 35, 2 -0.113 0.265 0.67 0.1742 0.893 0.532 1.5 0.357 0.706 0.613 0.2128 1.43 0.359 5.7 -0.096 0.874 0.913 0.03975 0.908 0.164 5.04 -0.271 0.837 0.746 0.1274 0.762 0.148 3.93 PRS_PLINK_0.0199526231496888 TRUE 145.2 Cancer of tongue Both 124 1319 2 neoplasms darkcyan 1319, 124 330, 33 330, 27 329, 33 330, 31 -0.0312 0.096 0.745 0.1278 0.969 0.803 1.17 -0.167 0.27 0.535 0.2715 0.846 0.498 1.44 -0.0233 0.263 0.929 0.0318 0.977 0.584 1.63 -0.0616 0.272 0.821 0.08571 0.94 0.551 1.6 PRS_PLINK_0.0199526231496888 FALSE 145.3 Cancer of major salivary glands Both 75 791 2 neoplasms darkcyan 791, 75 197, 23 198, 14 197, 20 198, 18 -0.0864 0.122 0.48 0.3188 0.917 0.722 1.17 -0.482 0.347 0.165 0.7831 0.618 0.313 1.22 -0.263 0.325 0.418 0.3788 0.768 0.406 1.45 -0.115 0.342 0.737 0.1325 0.891 0.456 1.74 PRS_PLINK_0.0199526231496888 FALSE 145.4 Cancer of the gums Both 25 293 2 neoplasms darkcyan 293, 25 74, 9 73, 3 73, 9 73, 4 -0.167 0.198 0.399 0.3994 0.846 0.573 1.25 -1.02 0.613 0.0969 1.014 0.362 0.109 1.2 0.11 0.492 0.824 0.08427 1.12 0.425 2.93 -0.817 0.59 0.166 0.7791 0.442 0.139 1.4 PRS_PLINK_0.0199526231496888 TRUE 145.5 Cancer of the mouth floor Both 34 416 2 neoplasms darkcyan 416, 34 104, 7 104, 10 104, 10 104, 7 -0.145 0.18 0.42 0.3763 0.865 0.608 1.23 0.461 0.504 0.361 0.443 1.59 0.59 4.26 0.391 0.492 0.427 0.3694 1.48 0.563 3.88 0.00216 0.529 0.997 0.001414 1 0.355 2.83 PRS_PLINK_0.0199526231496888 TRUE 149 Cancer of larynx, pharynx, nasal cavities Both 276 2681 2 neoplasms darkcyan 2681, 276 670, 77 670, 56 670, 67 670, 76 -0.0118 0.0626 0.851 0.07002 0.988 0.874 1.12 -0.299 0.183 0.103 0.989 0.742 0.518 1.06 -0.113 0.177 0.524 0.2805 0.894 0.632 1.26 -0.0486 0.178 0.784 0.1054 0.953 0.673 1.35 PRS_PLINK_0.0199526231496888 FALSE 149.1 Cancer of oropharynx Both 76 689 2 neoplasms darkcyan 689, 76 173, 17 172, 16 172, 17 172, 26 0.0681 0.125 0.586 0.2319 1.07 0.838 1.37 -0.0143 0.355 0.968 0.01418 0.986 0.491 1.98 0.0853 0.358 0.812 0.09049 1.09 0.539 2.2 0.333 0.338 0.324 0.4897 1.4 0.72 2.71 PRS_PLINK_0.0199526231496888 FALSE 149.2 Cancer of nasopharynx Both 28 262 2 neoplasms darkcyan 262, 28 66, 10 65, 5 65, 3 66, 10 -0.0675 0.208 0.746 0.1275 0.935 0.622 1.41 -0.494 0.536 0.356 0.4484 0.61 0.214 1.74 -0.976 0.603 0.106 0.9752 0.377 0.116 1.23 0.057 0.487 0.907 0.04246 1.06 0.408 2.75 PRS_PLINK_0.0199526231496888 TRUE 149.3 Cancer of hypopharynx Both 20 158 2 neoplasms darkcyan 158, 20 40, 5 39, 6 39, 4 40, 5 -0.212 0.24 0.378 0.4226 0.809 0.505 1.3 0.188 0.598 0.753 0.123 1.21 0.374 3.9 -0.299 0.681 0.661 0.1798 0.742 0.195 2.82 0.0579 0.662 0.93 0.03134 1.06 0.289 3.88 PRS_PLINK_0.0199526231496888 TRUE 149.4 Cancer of larynx Both 81 816 2 neoplasms darkcyan 816, 81 204, 17 204, 15 204, 20 204, 29 0.176 0.113 0.119 0.9246 1.19 0.956 1.49 -0.0992 0.355 0.78 0.108 0.906 0.452 1.81 0.135 0.336 0.688 0.1622 1.14 0.592 2.21 0.469 0.332 0.157 0.8029 1.6 0.834 3.07 PRS_PLINK_0.0199526231496888 FALSE 149.5 Hx of malignant neoplasm of oral cavity and pharynx Both 126 1129 2 neoplasms darkcyan 1129, 126 283, 43 282, 27 282, 29 282, 27 -0.191 0.0947 0.0434 1.362 0.826 0.686 0.994 -0.447 0.259 0.084 1.076 0.64 0.385 1.06 -0.443 0.256 0.0841 1.075 0.642 0.388 1.06 -0.493 0.267 0.0646 1.19 0.611 0.362 1.03 PRS_PLINK_0.0199526231496888 FALSE 149.9 Cancer of of nasal cavities Both 39 503 2 neoplasms darkcyan 503, 39 126, 10 126, 11 125, 11 126, 7 -0.116 0.167 0.485 0.3138 0.89 0.642 1.23 0.223 0.446 0.618 0.2093 1.25 0.521 3 0.21 0.445 0.636 0.1964 1.23 0.516 2.95 -0.163 0.533 0.76 0.1195 0.85 0.299 2.41 PRS_PLINK_0.0199526231496888 TRUE 150 Cancer of esophagus Both 156 821 2 neoplasms darkcyan 821, 156 206, 44 205, 28 205, 42 205, 42 0.0167 0.0884 0.85 0.07072 1.02 0.855 1.21 -0.45 0.262 0.0855 1.068 0.638 0.382 1.06 -0.0491 0.24 0.838 0.07679 0.952 0.595 1.52 -0.0837 0.249 0.737 0.1325 0.92 0.564 1.5 PRS_PLINK_0.0199526231496888 FALSE 151 Cancer of stomach Both 148 969 2 neoplasms darkcyan 969, 148 243, 38 242, 43 242, 31 242, 36 -0.0223 0.0862 0.796 0.09896 0.978 0.826 1.16 0.0572 0.243 0.814 0.08957 1.06 0.658 1.7 -0.198 0.258 0.442 0.3544 0.82 0.495 1.36 -0.015 0.262 0.954 0.02031 0.985 0.589 1.65 PRS_PLINK_0.0199526231496888 FALSE 153 Colorectal cancer Both 340 3013 2 neoplasms darkcyan 3013, 340 754, 74 753, 90 753, 83 753, 92 0.0496 0.0585 0.396 0.402 1.05 0.937 1.18 0.199 0.164 0.224 0.6501 1.22 0.885 1.68 0.115 0.168 0.494 0.3066 1.12 0.807 1.56 0.199 0.17 0.241 0.618 1.22 0.875 1.7 PRS_PLINK_0.0199526231496888 FALSE 153.2 Colon cancer Both 270 2265 2 neoplasms darkcyan 2265, 270 567, 59 566, 74 566, 62 566, 75 0.0687 0.0658 0.296 0.5282 1.07 0.942 1.22 0.224 0.183 0.221 0.6549 1.25 0.874 1.79 0.045 0.191 0.814 0.0893 1.05 0.719 1.52 0.174 0.19 0.36 0.444 1.19 0.82 1.73 PRS_PLINK_0.0199526231496888 FALSE 153.3 Malignant neoplasm of rectum, rectosigmoid junction, and anus Both 207 1771 2 neoplasms darkcyan 1771, 207 443, 34 443, 53 442, 61 443, 58 0.109 0.0747 0.146 0.836 1.11 0.963 1.29 0.425 0.227 0.0614 1.212 1.53 0.98 2.39 0.605 0.224 0.00693 2.16 1.83 1.18 2.84 0.576 0.232 0.0129 1.89 1.78 1.13 2.8 PRS_PLINK_0.0199526231496888 FALSE 155 Cancer of liver and intrahepatic bile duct Both 129 1113 2 neoplasms darkcyan 1113, 129 279, 32 278, 30 278, 27 278, 40 0.154 0.0963 0.11 0.9605 1.17 0.966 1.41 -0.0645 0.267 0.809 0.0921 0.938 0.556 1.58 -0.233 0.28 0.405 0.3923 0.792 0.458 1.37 0.104 0.269 0.7 0.1548 1.11 0.654 1.88 PRS_PLINK_0.0199526231496888 FALSE 155.1 Malignant neoplasm of liver, primary Both 89 722 2 neoplasms darkcyan 722, 89 181, 23 180, 19 180, 19 181, 28 0.143 0.119 0.229 0.6406 1.15 0.914 1.46 -0.169 0.326 0.605 0.2184 0.845 0.446 1.6 -0.238 0.333 0.474 0.3239 0.788 0.41 1.51 0.0511 0.324 0.875 0.05817 1.05 0.558 1.99 PRS_PLINK_0.0199526231496888 FALSE 157 Pancreatic cancer Both 134 1038 2 neoplasms darkcyan 1038, 134 260, 40 259, 29 259, 23 260, 42 0.0624 0.0953 0.512 0.2903 1.06 0.883 1.28 -0.343 0.257 0.182 0.7391 0.71 0.429 1.17 -0.518 0.276 0.0603 1.219 0.596 0.347 1.02 0.0906 0.244 0.71 0.1489 1.09 0.679 1.76 PRS_PLINK_0.0199526231496888 FALSE 158 Neoplasm of unspecified nature of digestive system Both 372 3386 2 neoplasms darkcyan 3386, 372 847, 82 846, 103 846, 83 847, 104 0.0516 0.0562 0.358 0.4462 1.05 0.943 1.18 0.217 0.156 0.163 0.7872 1.24 0.916 1.69 -0.00536 0.165 0.974 0.01143 0.995 0.72 1.37 0.235 0.162 0.147 0.8322 1.26 0.921 1.74 PRS_PLINK_0.0199526231496888 FALSE 159 Malignant neoplasm of other and ill-defined sites within the digestive organs and peritoneum Both 470 3774 2 neoplasms darkcyan 3774, 470 944, 105 943, 120 943, 116 944, 128 0.0602 0.0494 0.224 0.6504 1.06 0.964 1.17 0.137 0.141 0.331 0.4801 1.15 0.87 1.51 0.0895 0.143 0.533 0.2736 1.09 0.826 1.45 0.202 0.144 0.161 0.7923 1.22 0.923 1.62 PRS_PLINK_0.0199526231496888 FALSE 159.2 Malignant neoplasm of small intestine, including duodenum Both 49 476 2 neoplasms darkcyan 476, 49 119, 8 119, 18 119, 8 119, 15 0.129 0.148 0.382 0.4175 1.14 0.852 1.52 0.728 0.422 0.0844 1.073 2.07 0.906 4.74 0.058 0.478 0.903 0.04411 1.06 0.415 2.7 0.693 0.445 0.119 0.9241 2 0.836 4.78 PRS_PLINK_0.0199526231496888 TRUE 159.3 Malignant neoplasm of gallbladder and extrahepatic bile ducts Both 49 300 2 neoplasms darkcyan 300, 49 75, 14 75, 8 75, 18 75, 9 0.0421 0.161 0.793 0.1005 1.04 0.761 1.43 -0.623 0.459 0.175 0.7567 0.537 0.218 1.32 0.217 0.383 0.571 0.2432 1.24 0.587 2.63 -0.518 0.458 0.258 0.5889 0.596 0.243 1.46 PRS_PLINK_0.0199526231496888 TRUE 159.4 Malignant neoplasm of retroperitoneum and peritoneum Both 93 705 2 neoplasms darkcyan 705, 93 177, 28 176, 25 176, 18 176, 22 0.00769 0.114 0.946 0.02394 1.01 0.805 1.26 -0.128 0.303 0.673 0.1721 0.88 0.486 1.59 -0.469 0.323 0.147 0.8328 0.626 0.332 1.18 -0.144 0.316 0.649 0.1879 0.866 0.467 1.61 PRS_PLINK_0.0199526231496888 FALSE 164 Cancer of intrathoracic organs Both 48 294 2 neoplasms darkcyan 294, 48 74, 16 73, 13 73, 7 74, 12 -0.0434 0.154 0.778 0.1088 0.958 0.708 1.3 -0.281 0.419 0.503 0.2983 0.755 0.332 1.72 -0.897 0.481 0.0623 1.205 0.408 0.159 1.05 -0.185 0.427 0.664 0.1778 0.831 0.36 1.92 PRS_PLINK_0.0199526231496888 TRUE 165 Cancer within the respiratory system Both 350 2628 2 neoplasms darkcyan 2628, 350 657, 95 657, 84 657, 87 657, 84 -0.0534 0.0576 0.354 0.4511 0.948 0.847 1.06 -0.107 0.159 0.502 0.2993 0.899 0.657 1.23 -0.1 0.161 0.533 0.273 0.905 0.66 1.24 -0.0842 0.165 0.609 0.2151 0.919 0.666 1.27 PRS_PLINK_0.0199526231496888 FALSE 165.1 Cancer of bronchus; lung Both 289 2052 2 neoplasms darkcyan 2052, 289 513, 82 513, 64 513, 72 513, 71 -0.0541 0.0636 0.395 0.4032 0.947 0.836 1.07 -0.236 0.178 0.186 0.7314 0.79 0.557 1.12 -0.16 0.176 0.364 0.4384 0.852 0.604 1.2 -0.106 0.181 0.558 0.2537 0.899 0.631 1.28 PRS_PLINK_0.0199526231496888 FALSE 170 Cancer of bone and connective tissue Both 426 3932 2 neoplasms darkcyan 3932, 426 983, 104 983, 101 983, 119 983, 102 0.0227 0.0516 0.659 0.1808 1.02 0.925 1.13 -0.00335 0.147 0.982 0.007964 0.997 0.747 1.33 0.181 0.143 0.207 0.6842 1.2 0.905 1.59 -0.0416 0.152 0.784 0.1057 0.959 0.712 1.29 PRS_PLINK_0.0199526231496888 FALSE 170.1 Bone cancer Both 183 1665 2 neoplasms darkcyan 1665, 183 417, 44 416, 40 416, 58 416, 41 0.0266 0.0772 0.731 0.1362 1.03 0.883 1.19 -0.0857 0.226 0.705 0.1519 0.918 0.589 1.43 0.317 0.212 0.135 0.8707 1.37 0.906 2.08 -0.0321 0.234 0.891 0.05011 0.968 0.612 1.53 PRS_PLINK_0.0199526231496888 FALSE 170.2 Cancer of connective tissue Both 322 2816 2 neoplasms darkcyan 2816, 322 704, 81 704, 78 704, 85 704, 78 0.00581 0.0588 0.921 0.03559 1.01 0.896 1.13 -0.022 0.167 0.895 0.04801 0.978 0.705 1.36 0.0768 0.166 0.643 0.1915 1.08 0.78 1.49 -0.0779 0.174 0.654 0.1841 0.925 0.658 1.3 PRS_PLINK_0.0199526231496888 FALSE 172 Skin cancer Both 1620 9111 2 neoplasms darkcyan 9111, 1620 2277, 437 2278, 418 2277, 422 2278, 343 -0.0476 0.0282 0.0917 1.038 0.954 0.902 1.01 0.0184 0.0766 0.81 0.09148 1.02 0.877 1.18 0.0124 0.0779 0.873 0.05884 1.01 0.869 1.18 -0.123 0.0833 0.139 0.8573 0.884 0.751 1.04 PRS_PLINK_0.0199526231496888 FALSE 172.1 Melanomas of skin, dx or hx Both 972 7834 2 neoplasms darkcyan 7834, 972 1958, 274 1958, 242 1958, 251 1959, 205 -0.0565 0.0351 0.107 0.9702 0.945 0.882 1.01 -0.0723 0.0948 0.446 0.3506 0.93 0.772 1.12 -0.0599 0.0956 0.531 0.2749 0.942 0.781 1.14 -0.232 0.103 0.0241 1.617 0.793 0.648 0.97 PRS_PLINK_0.0199526231496888 FALSE 172.11 Melanomas of skin Both 530 6234 2 neoplasms darkcyan 6234, 530 1559, 138 1558, 143 1558, 132 1559, 117 -0.0355 0.0462 0.443 0.3539 0.965 0.882 1.06 0.056 0.125 0.653 0.1852 1.06 0.829 1.35 -0.0722 0.129 0.574 0.2411 0.93 0.723 1.2 -0.196 0.136 0.15 0.8225 0.822 0.63 1.07 PRS_PLINK_0.0199526231496888 FALSE 172.2 Other non-epithelial cancer of skin Both 1316 7859 2 neoplasms darkcyan 7859, 1316 1964, 351 1965, 336 1964, 346 1965, 283 -0.0578 0.031 0.0623 1.205 0.944 0.888 1 0.0169 0.0848 0.842 0.07458 1.02 0.861 1.2 0.0414 0.0855 0.628 0.2017 1.04 0.881 1.23 -0.121 0.0913 0.185 0.7331 0.886 0.741 1.06 PRS_PLINK_0.0199526231496888 FALSE 172.21 Basal cell carcinoma Both 650 5535 2 neoplasms darkcyan 5535, 650 1383, 170 1384, 173 1383, 163 1384, 144 -0.0485 0.0424 0.252 0.5979 0.953 0.877 1.04 0.0512 0.116 0.658 0.1817 1.05 0.839 1.32 -0.0259 0.118 0.826 0.08281 0.974 0.773 1.23 -0.161 0.125 0.196 0.7083 0.851 0.667 1.09 PRS_PLINK_0.0199526231496888 FALSE 172.22 Squamous cell carcinoma Both 402 3581 2 neoplasms darkcyan 3581, 402 896, 106 895, 98 895, 113 895, 85 -0.0649 0.0536 0.225 0.647 0.937 0.844 1.04 -0.0413 0.149 0.781 0.1075 0.959 0.717 1.28 0.1 0.145 0.49 0.31 1.11 0.832 1.47 -0.204 0.158 0.197 0.7062 0.815 0.598 1.11 PRS_PLINK_0.0199526231496888 FALSE 172.3 Carcinoma in situ of skin Both 238 2475 2 neoplasms darkcyan 2475, 238 619, 67 619, 56 618, 61 619, 54 -0.0818 0.0695 0.239 0.6219 0.921 0.804 1.06 -0.147 0.188 0.436 0.3604 0.864 0.597 1.25 -0.0683 0.188 0.717 0.1447 0.934 0.646 1.35 -0.19 0.198 0.336 0.4742 0.827 0.561 1.22 PRS_PLINK_0.0199526231496888 FALSE 173 Neoplasm of uncertain behavior of skin Both 449 4788 2 neoplasms darkcyan 4788, 449 1196, 126 1197, 111 1197, 120 1197, 92 -0.116 0.0511 0.0238 1.624 0.891 0.806 0.985 -0.12 0.136 0.38 0.4205 0.887 0.679 1.16 -0.0594 0.135 0.661 0.1798 0.942 0.723 1.23 -0.339 0.148 0.0223 1.651 0.712 0.533 0.953 PRS_PLINK_0.0199526231496888 FALSE 174 Breast cancer Both 918 4932 2 neoplasms darkcyan 4932, 918 1232, 253 1233, 241 1233, 221 1233, 203 -0.0669 0.0377 0.0756 1.121 0.935 0.869 1.01 -0.0107 0.101 0.915 0.03848 0.989 0.812 1.21 -0.101 0.103 0.327 0.4858 0.904 0.738 1.11 -0.124 0.108 0.251 0.6003 0.884 0.715 1.09 PRS_PLINK_0.0199526231496888 FALSE 174.1 Breast cancer [female] Female 873 4758 2 neoplasms darkcyan 4758, 873 1189, 244 1189, 226 1189, 214 1190, 189 -0.0743 0.0386 0.0541 1.266 0.928 0.861 1 -0.0436 0.103 0.672 0.1725 0.957 0.782 1.17 -0.103 0.105 0.325 0.4875 0.902 0.734 1.11 -0.166 0.111 0.134 0.8715 0.847 0.682 1.05 PRS_PLINK_0.0199526231496888 FALSE 174.11 Malignant neoplasm of female breast Female 854 4725 2 neoplasms darkcyan 4725, 854 1181, 241 1181, 222 1181, 209 1181, 182 -0.0794 0.0389 0.0414 1.383 0.924 0.856 0.997 -0.0541 0.104 0.602 0.2204 0.947 0.773 1.16 -0.114 0.106 0.282 0.5493 0.892 0.725 1.1 -0.19 0.112 0.0892 1.05 0.827 0.664 1.03 PRS_PLINK_0.0199526231496888 FALSE 174.3 Neoplasm of uncertain behavior of breast Both 72 622 2 neoplasms darkcyan 622, 72 156, 28 155, 16 155, 13 156, 15 -0.251 0.135 0.0637 1.196 0.778 0.597 1.01 -0.635 0.353 0.0721 1.142 0.53 0.265 1.06 -0.698 0.346 0.0439 1.358 0.498 0.253 0.981 PRS_PLINK_0.0199526231496888 FALSE 175 Acquired absence of breast Female 322 2794 2 neoplasms darkcyan 2794, 322 698, 94 698, 85 698, 79 699, 64 -0.105 0.0613 0.0868 1.062 0.9 0.799 1.02 -0.0951 0.159 0.55 0.2599 0.909 0.666 1.24 -0.125 0.164 0.445 0.3517 0.882 0.64 1.22 -0.399 0.176 0.0234 1.631 0.671 0.475 0.947 PRS_PLINK_0.0199526231496888 FALSE 180 Cervical cancer and dysplasia Female 611 4514 2 neoplasms darkcyan 4514, 611 1128, 140 1128, 164 1128, 151 1129, 156 0.00351 0.0448 0.938 0.02801 1 0.919 1.1 0.146 0.123 0.235 0.6297 1.16 0.91 1.47 0.0555 0.127 0.663 0.1786 1.06 0.824 1.36 0.0319 0.129 0.805 0.09429 1.03 0.802 1.33 PRS_PLINK_0.0199526231496888 FALSE 180.1 Cervical cancer Female 182 1626 2 neoplasms darkcyan 1626, 182 407, 40 406, 50 406, 42 407, 50 0.0385 0.0807 0.633 0.1983 1.04 0.887 1.22 0.214 0.222 0.335 0.4756 1.24 0.802 1.91 0.0444 0.234 0.849 0.071 1.05 0.661 1.65 0.175 0.233 0.452 0.3445 1.19 0.754 1.88 PRS_PLINK_0.0199526231496888 FALSE 180.3 Cervical intraepithelial neoplasia [CIN] [Cervical dysplasia] Female 489 3794 2 neoplasms darkcyan 3794, 489 948, 125 948, 130 948, 119 949, 115 -0.0176 0.0495 0.723 0.141 0.983 0.892 1.08 0.0357 0.133 0.789 0.1031 1.04 0.798 1.35 -0.0583 0.138 0.673 0.1717 0.943 0.719 1.24 -0.129 0.142 0.364 0.4393 0.879 0.665 1.16 PRS_PLINK_0.0199526231496888 FALSE 182 Malignant neoplasm of uterus Female 172 1953 2 neoplasms darkcyan 1953, 172 489, 43 488, 48 488, 34 488, 47 0.00732 0.0815 0.928 0.03227 1.01 0.859 1.18 0.12 0.218 0.581 0.2356 1.13 0.736 1.73 -0.28 0.238 0.24 0.6203 0.756 0.474 1.21 0.00672 0.225 0.976 0.01049 1.01 0.648 1.56 PRS_PLINK_0.0199526231496888 FALSE 184 Cancer of other female genital organs Female 359 3328 2 neoplasms darkcyan 3328, 359 831, 81 832, 99 832, 86 832, 93 0.0217 0.0581 0.709 0.1495 1.02 0.912 1.15 0.214 0.158 0.175 0.7581 1.24 0.909 1.69 0.0176 0.163 0.914 0.03888 1.02 0.739 1.4 0.0782 0.166 0.638 0.1951 1.08 0.781 1.5 PRS_PLINK_0.0199526231496888 FALSE 184.1 Malignant neoplasm of ovary and other uterine adnexa Female 186 1597 2 neoplasms darkcyan 1597, 186 400, 42 399, 57 399, 44 399, 43 -0.0303 0.0814 0.71 0.1487 0.97 0.827 1.14 0.301 0.215 0.161 0.7931 1.35 0.887 2.06 0.0334 0.23 0.885 0.05322 1.03 0.659 1.62 -0.0705 0.24 0.769 0.1143 0.932 0.583 1.49 PRS_PLINK_0.0199526231496888 FALSE 184.11 Malignant neoplasm of ovary Female 147 1267 2 neoplasms darkcyan 1267, 147 317, 33 317, 43 316, 39 317, 32 -0.0364 0.0912 0.69 0.1613 0.964 0.806 1.15 0.25 0.245 0.308 0.5117 1.28 0.794 2.07 0.17 0.253 0.501 0.3005 1.19 0.722 1.95 -0.157 0.272 0.565 0.2481 0.855 0.501 1.46 PRS_PLINK_0.0199526231496888 FALSE 184.2 Cancer of other female genital organs (excluding uterus and ovary) Female 169 1695 2 neoplasms darkcyan 1695, 169 423, 35 424, 47 423, 36 424, 51 0.105 0.0837 0.212 0.6747 1.11 0.942 1.31 0.255 0.233 0.274 0.5625 1.29 0.817 2.04 -0.0664 0.247 0.788 0.1034 0.936 0.577 1.52 0.304 0.239 0.204 0.6907 1.35 0.848 2.16 PRS_PLINK_0.0199526231496888 FALSE 185 Cancer of prostate Male 387 1924 2 neoplasms darkcyan 1924, 387 481, 109 481, 107 481, 91 481, 80 -0.0869 0.0584 0.137 0.8645 0.917 0.818 1.03 0.0199 0.156 0.899 0.04638 1.02 0.751 1.39 -0.156 0.166 0.347 0.4591 0.856 0.619 1.18 -0.287 0.176 0.102 0.9894 0.751 0.532 1.06 PRS_PLINK_0.0199526231496888 FALSE 187 Cancer of other male genital organs Male 62 683 2 neoplasms darkcyan 683, 62 171, 16 171, 16 170, 18 171, 12 -0.0259 0.131 0.843 0.07414 0.974 0.754 1.26 -0.0778 0.363 0.83 0.08079 0.925 0.454 1.88 0.0703 0.354 0.842 0.07447 1.07 0.536 2.15 0.0358 0.403 0.929 0.0319 1.04 0.471 2.28 PRS_PLINK_0.0199526231496888 FALSE 187.1 Malignant neoplasm of unspecified male genital organ Male 22 205 2 neoplasms darkcyan 205, 22 52, 8 51, 4 51, 6 51, 4 -0.103 0.229 0.652 0.186 0.902 0.575 1.41 -0.612 0.609 0.315 0.5016 0.542 0.164 1.79 -0.344 0.572 0.548 0.2615 0.709 0.231 2.17 -0.514 0.625 0.411 0.3865 0.598 0.176 2.03 PRS_PLINK_0.0199526231496888 TRUE 187.2 Malignant neoplasm of testis Male 33 378 2 neoplasms darkcyan 378, 33 95, 5 94, 10 94, 11 95, 7 0.0915 0.179 0.609 0.215 1.1 0.771 1.56 0.719 0.527 0.172 0.7639 2.05 0.731 5.77 0.65 0.51 0.202 0.6939 1.92 0.705 5.2 0.587 0.61 0.336 0.4736 1.8 0.544 5.95 PRS_PLINK_0.0199526231496888 TRUE 187.8 Neoplasm of uncertain behavior of male genital organs Male 10 100 2 neoplasms darkcyan 100, 10 25, 4 25, 2 25, 2 25, 2 -0.156 0.363 0.667 0.1759 0.855 0.42 1.74 -0.875 0.875 0.317 0.4984 0.417 0.075 2.32 -1.95 1.3 0.133 0.8775 0.142 0.0111 1.81 0.0397 1.01 0.969 0.0138 1.04 0.143 7.56 PRS_PLINK_0.0199526231496888 TRUE 189 Cancer of urinary organs (incl. kidney and bladder) Both 538 4911 2 neoplasms darkcyan 4911, 538 1228, 133 1228, 109 1227, 146 1228, 150 0.0965 0.0463 0.037 1.432 1.1 1.01 1.21 -0.186 0.135 0.169 0.7719 0.83 0.637 1.08 0.125 0.128 0.33 0.4816 1.13 0.881 1.46 0.175 0.131 0.183 0.7385 1.19 0.921 1.54 PRS_PLINK_0.0199526231496888 FALSE 189.1 Cancer of kidney and renal pelvis Both 271 2928 2 neoplasms darkcyan 2928, 271 732, 65 732, 55 732, 74 732, 77 0.119 0.0639 0.0623 1.205 1.13 0.994 1.28 -0.15 0.19 0.428 0.3685 0.861 0.594 1.25 0.158 0.179 0.377 0.4236 1.17 0.825 1.66 0.17 0.182 0.349 0.4569 1.19 0.83 1.69 PRS_PLINK_0.0199526231496888 FALSE 189.11 Malignant neoplasm of kidney, except pelvis Both 228 2540 2 neoplasms darkcyan 2540, 228 635, 54 635, 45 635, 65 635, 64 0.103 0.0703 0.142 0.8492 1.11 0.966 1.27 -0.166 0.208 0.426 0.3704 0.847 0.564 1.27 0.213 0.194 0.272 0.5661 1.24 0.847 1.81 0.189 0.2 0.346 0.4605 1.21 0.816 1.79 PRS_PLINK_0.0199526231496888 FALSE 189.12 Malignant neoplasm of renal pelvis Both 38 429 2 neoplasms darkcyan 429, 38 108, 9 107, 13 107, 6 107, 10 -0.0999 0.166 0.548 0.2611 0.905 0.653 1.25 0.281 0.452 0.534 0.2722 1.32 0.546 3.21 -0.605 0.529 0.253 0.5975 0.546 0.194 1.54 -0.0362 0.498 0.942 0.02592 0.964 0.363 2.56 PRS_PLINK_0.0199526231496888 TRUE 189.2 Cancer of bladder Both 304 2895 2 neoplasms darkcyan 2895, 304 724, 75 724, 67 723, 81 724, 81 0.0533 0.061 0.382 0.4176 1.05 0.936 1.19 -0.0984 0.176 0.575 0.2404 0.906 0.642 1.28 0.0853 0.17 0.616 0.2103 1.09 0.78 1.52 0.136 0.176 0.44 0.3566 1.15 0.812 1.62 PRS_PLINK_0.0199526231496888 FALSE 189.21 Malignant neoplasm of bladder Both 277 2657 2 neoplasms darkcyan 2657, 277 665, 70 664, 59 664, 70 664, 78 0.053 0.0637 0.406 0.3917 1.05 0.931 1.19 -0.149 0.184 0.417 0.3796 0.861 0.6 1.24 0.0191 0.179 0.915 0.03851 1.02 0.718 1.45 0.172 0.18 0.338 0.4705 1.19 0.835 1.69 PRS_PLINK_0.0199526231496888 FALSE 189.4 Malignant neoplasm of other urinary organs Both 119 1128 2 neoplasms darkcyan 1128, 119 282, 34 282, 25 282, 32 282, 28 -0.0782 0.0973 0.422 0.3752 0.925 0.764 1.12 -0.304 0.275 0.269 0.571 0.738 0.431 1.26 -0.0552 0.262 0.833 0.07924 0.946 0.566 1.58 -0.0861 0.275 0.754 0.1226 0.918 0.535 1.57 PRS_PLINK_0.0199526231496888 FALSE 190 Cancer of eye Both 28 276 2 neoplasms darkcyan 276, 28 69, 6 69, 11 69, 9 69, 2 -0.363 0.208 0.0807 1.093 0.695 0.462 1.05 0.462 0.515 0.369 0.4326 1.59 0.579 4.36 0.329 0.528 0.534 0.2727 1.39 0.494 3.91 -0.88 0.694 0.205 0.6885 0.415 0.106 1.62 PRS_PLINK_0.0199526231496888 TRUE 191 Manlignant and unknown neoplasms of brain and nervous system Both 282 2847 2 neoplasms darkcyan 2847, 282 712, 73 712, 59 711, 70 712, 80 0.0583 0.0646 0.367 0.4352 1.06 0.934 1.2 -0.168 0.182 0.356 0.4489 0.845 0.591 1.21 -0.0233 0.178 0.896 0.04769 0.977 0.689 1.38 0.118 0.178 0.507 0.2951 1.13 0.794 1.59 PRS_PLINK_0.0199526231496888 FALSE 191.1 Cancer of brain and nervous system Both 198 1864 2 neoplasms darkcyan 1864, 198 466, 43 466, 45 466, 53 466, 57 0.112 0.076 0.139 0.8561 1.12 0.964 1.3 0.106 0.222 0.635 0.1972 1.11 0.719 1.72 0.226 0.217 0.297 0.5266 1.25 0.819 1.92 0.298 0.223 0.18 0.744 1.35 0.871 2.08 PRS_PLINK_0.0199526231496888 FALSE 191.11 Cancer of brain Both 171 1651 2 neoplasms darkcyan 1651, 171 413, 38 413, 35 412, 49 413, 49 0.132 0.0813 0.105 0.9806 1.14 0.973 1.34 -0.062 0.241 0.797 0.09859 0.94 0.586 1.51 0.288 0.229 0.208 0.6821 1.33 0.852 2.09 0.308 0.238 0.196 0.7072 1.36 0.853 2.17 PRS_PLINK_0.0199526231496888 FALSE 193 Thyroid cancer Both 193 2880 2 neoplasms darkcyan 2880, 193 719, 48 720, 38 720, 44 720, 63 0.0771 0.0768 0.315 0.5013 1.08 0.929 1.26 -0.231 0.221 0.295 0.5299 0.794 0.515 1.22 -0.111 0.216 0.607 0.217 0.895 0.587 1.37 0.198 0.207 0.337 0.4721 1.22 0.813 1.83 PRS_PLINK_0.0199526231496888 FALSE 194 Cancer of other endocrine glands Both 159 1685 2 neoplasms darkcyan 1685, 159 422, 35 421, 39 421, 39 421, 46 0.0774 0.0854 0.365 0.4378 1.08 0.914 1.28 0.0568 0.244 0.816 0.08815 1.06 0.656 1.71 0.01 0.247 0.968 0.01428 1.01 0.623 1.64 0.187 0.247 0.448 0.3484 1.21 0.743 1.96 PRS_PLINK_0.0199526231496888 FALSE 195 Cancer, suspected or other Both 3794 7948 2 neoplasms darkcyan 7948, 3794 1986, 990 1987, 958 1987, 943 1987, 903 0.00415 0.0215 0.847 0.07223 1 0.963 1.05 0.0226 0.0596 0.704 0.1522 1.02 0.91 1.15 -0.00759 0.0602 0.9 0.04597 0.992 0.882 1.12 0.0222 0.0624 0.722 0.1416 1.02 0.905 1.16 PRS_PLINK_0.0199526231496888 FALSE 195.1 Malignant neoplasm, other Both 3724 7943 2 neoplasms darkcyan 7943, 3724 1985, 978 1986, 943 1985, 922 1986, 881 0.00149 0.0216 0.945 0.02458 1 0.96 1.04 0.0215 0.0599 0.72 0.1428 1.02 0.909 1.15 -0.0142 0.0606 0.815 0.08905 0.986 0.876 1.11 0.0127 0.0628 0.839 0.07602 1.01 0.895 1.15 PRS_PLINK_0.0199526231496888 FALSE 195.3 Malignant neoplasm of head, face, and neck Both 231 2037 2 neoplasms darkcyan 2037, 231 510, 57 509, 49 509, 67 509, 58 -0.0247 0.0705 0.726 0.139 0.976 0.85 1.12 -0.151 0.204 0.457 0.3397 0.86 0.577 1.28 0.158 0.192 0.411 0.3857 1.17 0.804 1.71 0.0254 0.204 0.901 0.04531 1.03 0.687 1.53 PRS_PLINK_0.0199526231496888 FALSE 196 Radiotherapy Both 585 4280 2 neoplasms darkcyan 4280, 585 1069, 143 1070, 158 1070, 139 1070, 145 0.0185 0.0449 0.68 0.1673 1.02 0.933 1.11 0.124 0.125 0.318 0.497 1.13 0.887 1.45 -0.0313 0.129 0.808 0.09248 0.969 0.753 1.25 0.00529 0.131 0.968 0.01421 1.01 0.777 1.3 PRS_PLINK_0.0199526231496888 FALSE 197 Chemotherapy Both 1436 6896 2 neoplasms darkcyan 6896, 1436 1723, 387 1724, 360 1724, 354 1724, 335 -0.0243 0.0302 0.42 0.3763 0.976 0.92 1.04 -0.0242 0.0834 0.772 0.1125 0.976 0.829 1.15 -0.0849 0.0846 0.315 0.5012 0.919 0.778 1.08 -0.0671 0.0881 0.446 0.3503 0.935 0.787 1.11 PRS_PLINK_0.0199526231496888 FALSE 198 Secondary malignant neoplasm Both 1393 6811 2 neoplasms darkcyan 6811, 1393 1702, 362 1703, 338 1702, 341 1703, 352 0.0317 0.0309 0.304 0.5173 1.03 0.972 1.1 -0.00668 0.086 0.938 0.02774 0.993 0.839 1.18 -0.0641 0.0873 0.463 0.3341 0.938 0.79 1.11 0.0928 0.0885 0.295 0.5305 1.1 0.922 1.31 PRS_PLINK_0.0199526231496888 FALSE 198.1 Secondary malignancy of lymph nodes Both 878 6020 2 neoplasms darkcyan 6020, 878 1504, 242 1505, 211 1505, 214 1505, 211 -0.00902 0.0372 0.808 0.09234 0.991 0.921 1.07 -0.0843 0.103 0.413 0.3843 0.919 0.751 1.12 -0.14 0.104 0.179 0.7475 0.869 0.709 1.07 -0.0473 0.107 0.657 0.1821 0.954 0.774 1.18 PRS_PLINK_0.0199526231496888 FALSE 198.2 Secondary malignancy of respiratory organs Both 297 2432 2 neoplasms darkcyan 2432, 297 607, 87 608, 64 608, 74 608, 72 -0.0614 0.0629 0.329 0.483 0.94 0.831 1.06 -0.297 0.174 0.0879 1.056 0.743 0.528 1.05 -0.206 0.171 0.227 0.644 0.814 0.582 1.14 -0.156 0.177 0.379 0.4217 0.855 0.604 1.21 PRS_PLINK_0.0199526231496888 FALSE 198.3 Secondary malignant neoplasm of digestive systems Both 247 1985 2 neoplasms darkcyan 1985, 247 497, 69 496, 63 496, 55 496, 60 -0.0539 0.0696 0.439 0.3579 0.948 0.827 1.09 -0.107 0.186 0.565 0.2481 0.898 0.623 1.29 -0.255 0.195 0.19 0.7211 0.775 0.529 1.13 -0.199 0.196 0.31 0.5084 0.82 0.559 1.2 PRS_PLINK_0.0199526231496888 FALSE 198.4 Secondary malignant neoplasm of liver Both 221 1762 2 neoplasms darkcyan 1762, 221 441, 56 440, 52 440, 51 441, 62 0.06 0.0728 0.41 0.387 1.06 0.921 1.22 -0.0616 0.202 0.761 0.1188 0.94 0.633 1.4 -0.115 0.207 0.578 0.2378 0.891 0.594 1.34 0.155 0.204 0.449 0.3478 1.17 0.782 1.74 PRS_PLINK_0.0199526231496888 FALSE 198.5 Secondary malignancy of brain/spine Both 166 1488 2 neoplasms darkcyan 1488, 166 372, 48 372, 42 372, 36 372, 40 -0.123 0.0848 0.147 0.8315 0.884 0.749 1.04 -0.167 0.223 0.454 0.3429 0.847 0.547 1.31 -0.358 0.234 0.127 0.8979 0.699 0.442 1.11 -0.277 0.239 0.246 0.6097 0.758 0.475 1.21 PRS_PLINK_0.0199526231496888 FALSE 198.6 Secondary malignancy of bone Both 240 1852 2 neoplasms darkcyan 1852, 240 463, 63 463, 57 463, 60 463, 60 -0.00274 0.0696 0.969 0.01387 0.997 0.87 1.14 -0.116 0.193 0.55 0.2594 0.891 0.61 1.3 -0.101 0.193 0.602 0.2204 0.904 0.619 1.32 -0.125 0.198 0.527 0.278 0.882 0.599 1.3 PRS_PLINK_0.0199526231496888 FALSE 198.7 Secondary malignant neoplasm of skin Both 99 713 2 neoplasms darkcyan 713, 99 179, 25 178, 28 178, 22 178, 24 -0.0223 0.11 0.839 0.07604 0.978 0.788 1.21 0.0992 0.292 0.734 0.1341 1.1 0.623 1.96 -0.157 0.313 0.616 0.2101 0.855 0.463 1.58 -0.0242 0.314 0.939 0.02754 0.976 0.528 1.8 PRS_PLINK_0.0199526231496888 FALSE 199 Neoplasm of uncertain behavior Both 1347 7743 2 neoplasms darkcyan 7743, 1347 1935, 344 1936, 336 1935, 343 1936, 324 0.0207 0.0307 0.5 0.3008 1.02 0.961 1.08 0.0142 0.0853 0.868 0.06135 1.01 0.858 1.2 0.0139 0.0856 0.871 0.05989 1.01 0.857 1.2 0.0139 0.0892 0.876 0.05726 1.01 0.851 1.21 PRS_PLINK_0.0199526231496888 FALSE 199.4 Neurofibromatosis Both 22 297 2 neoplasms darkcyan 297, 22 75, 8 74, 2 74, 7 74, 5 -0.0976 0.215 0.649 0.1876 0.907 0.595 1.38 -1.68 0.755 0.0257 1.59 0.186 0.0423 0.815 -0.177 0.517 0.732 0.1354 0.838 0.304 2.31 -0.726 0.603 0.229 0.6406 0.484 0.148 1.58 PRS_PLINK_0.0199526231496888 TRUE 200 Myeloproliferative disease Both 326 2629 2 neoplasms darkcyan 2629, 326 658, 70 657, 83 657, 83 657, 90 0.118 0.0604 0.0506 1.295 1.13 1 1.27 0.178 0.171 0.297 0.528 1.2 0.855 1.67 0.214 0.173 0.217 0.6632 1.24 0.882 1.74 0.219 0.174 0.208 0.6815 1.25 0.885 1.75 PRS_PLINK_0.0199526231496888 FALSE 200.1 Polycythemia vera Both 47 440 2 neoplasms darkcyan 440, 47 110, 15 110, 7 110, 11 110, 14 -0.0479 0.158 0.762 0.1181 0.953 0.699 1.3 -0.768 0.453 0.0898 1.047 0.464 0.191 1.13 -0.32 0.418 0.444 0.3527 0.726 0.32 1.65 -0.207 0.408 0.611 0.2137 0.813 0.365 1.81 PRS_PLINK_0.0199526231496888 TRUE 201 Hodgkin's disease Both 68 458 2 neoplasms darkcyan 458, 68 115, 12 114, 14 114, 25 115, 17 0.116 0.137 0.397 0.401 1.12 0.858 1.47 0.265 0.406 0.513 0.2895 1.3 0.589 2.89 0.774 0.382 0.0428 1.368 2.17 1.03 4.59 0.0719 0.395 0.856 0.06769 1.07 0.495 2.33 PRS_PLINK_0.0199526231496888 FALSE 202 Cancer of other lymphoid, histiocytic tissue Both 431 3541 2 neoplasms darkcyan 3541, 431 886, 99 885, 93 885, 125 885, 114 0.1 0.0529 0.0582 1.235 1.11 0.997 1.23 -0.0529 0.152 0.727 0.1382 0.948 0.704 1.28 0.205 0.145 0.156 0.808 1.23 0.925 1.63 0.0308 0.151 0.838 0.07675 1.03 0.768 1.39 PRS_PLINK_0.0199526231496888 FALSE 202.2 Non-Hodgkins lymphoma Both 373 2996 2 neoplasms darkcyan 2996, 373 749, 83 749, 78 749, 110 749, 102 0.0973 0.058 0.0935 1.029 1.1 0.984 1.23 -0.0281 0.166 0.865 0.06281 0.972 0.703 1.35 0.249 0.157 0.112 0.9502 1.28 0.943 1.74 0.11 0.163 0.5 0.3007 1.12 0.811 1.54 PRS_PLINK_0.0199526231496888 FALSE 202.21 Nodular lymphoma Both 194 1595 2 neoplasms darkcyan 1595, 194 399, 37 399, 51 398, 56 399, 50 0.11 0.0807 0.174 0.7603 1.12 0.953 1.31 0.337 0.226 0.135 0.8696 1.4 0.9 2.18 0.383 0.227 0.0911 1.04 1.47 0.94 2.29 0.157 0.236 0.506 0.2955 1.17 0.736 1.86 PRS_PLINK_0.0199526231496888 FALSE 202.22 Reticulosarcoma Both 48 346 2 neoplasms darkcyan 346, 48 87, 9 86, 7 86, 20 87, 12 0.239 0.164 0.145 0.8372 1.27 0.921 1.75 -0.187 0.509 0.714 0.1466 0.83 0.306 2.25 0.681 0.423 0.107 0.9692 1.98 0.862 4.53 0.209 0.476 0.661 0.1797 1.23 0.484 3.14 PRS_PLINK_0.0199526231496888 TRUE 202.24 Large cell lymphoma Both 48 299 2 neoplasms darkcyan 299, 48 75, 9 75, 10 74, 14 75, 15 0.212 0.162 0.193 0.7153 1.24 0.899 1.7 0.241 0.485 0.619 0.2084 1.27 0.492 3.29 0.354 0.474 0.456 0.3414 1.42 0.563 3.61 0.493 0.479 0.304 0.5168 1.64 0.64 4.19 PRS_PLINK_0.0199526231496888 TRUE 204 Leukemia Both 186 1454 2 neoplasms darkcyan 1454, 186 364, 37 363, 40 363, 55 364, 54 0.141 0.0791 0.0752 1.124 1.15 0.986 1.34 0.0886 0.237 0.708 0.15 1.09 0.687 1.74 0.38 0.225 0.0906 1.043 1.46 0.942 2.27 0.314 0.231 0.174 0.7591 1.37 0.87 2.15 PRS_PLINK_0.0199526231496888 FALSE 204.1 Lymphoid leukemia Both 64 480 2 neoplasms darkcyan 480, 64 120, 18 120, 13 120, 19 120, 14 -0.107 0.137 0.436 0.3601 0.899 0.687 1.18 -0.24 0.382 0.529 0.2762 0.787 0.372 1.66 -0.0989 0.364 0.786 0.1045 0.906 0.443 1.85 -0.544 0.405 0.179 0.746 0.581 0.263 1.28 PRS_PLINK_0.0199526231496888 FALSE 204.11 Lymphoid leukemia, acute Both 24 199 2 neoplasms darkcyan 199, 24 50, 6 50, 6 49, 9 50, 3 -0.102 0.209 0.624 0.2045 0.903 0.6 1.36 0.0689 0.565 0.903 0.04433 1.07 0.354 3.24 0.478 0.561 0.394 0.4044 1.61 0.537 4.84 -1.06 0.718 0.139 0.8558 0.346 0.0848 1.41 PRS_PLINK_0.0199526231496888 TRUE 204.12 Lymphoid leukemia, chronic Both 44 298 2 neoplasms darkcyan 298, 44 75, 11 74, 11 74, 11 75, 11 -0.0253 0.164 0.877 0.057 0.975 0.707 1.34 0.111 0.462 0.809 0.09191 1.12 0.452 2.76 -0.132 0.471 0.779 0.1084 0.876 0.348 2.21 -0.454 0.485 0.349 0.4568 0.635 0.245 1.64 PRS_PLINK_0.0199526231496888 TRUE 204.2 Myeloid leukemia Both 81 562 2 neoplasms darkcyan 562, 81 141, 18 140, 21 140, 25 141, 17 -0.00633 0.125 0.96 0.01787 0.994 0.777 1.27 0.134 0.337 0.691 0.1607 1.14 0.59 2.22 0.288 0.329 0.381 0.4188 1.33 0.7 2.54 0.145 0.366 0.693 0.1593 1.16 0.564 2.37 PRS_PLINK_0.0199526231496888 FALSE 204.21 Myeloid leukemia, acute Both 37 315 2 neoplasms darkcyan 315, 37 79, 7 79, 14 78, 10 79, 6 0.0237 0.18 0.895 0.04798 1.02 0.719 1.46 0.702 0.481 0.144 0.8417 2.02 0.787 5.18 0.376 0.492 0.444 0.3524 1.46 0.555 3.82 0.25 0.57 0.661 0.1799 1.28 0.42 3.92 PRS_PLINK_0.0199526231496888 TRUE 204.22 Myeloid leukemia, chronic Both 21 130 2 neoplasms darkcyan 130, 21 33, 5 32, 4 32, 6 33, 6 0.085 0.235 0.718 0.1441 1.09 0.687 1.73 -0.189 0.703 0.788 0.1035 0.828 0.209 3.28 -0.00364 0.681 0.996 0.001857 0.996 0.262 3.79 0.346 0.69 0.616 0.2104 1.41 0.366 5.46 PRS_PLINK_0.0199526231496888 TRUE 204.4 Multiple myeloma Both 52 416 2 neoplasms darkcyan 416, 52 104, 8 104, 8 104, 17 104, 19 0.397 0.154 0.01 1.999 1.49 1.1 2.01 0.107 0.497 0.829 0.08121 1.11 0.42 2.95 0.583 0.445 0.191 0.7196 1.79 0.748 4.29 0.797 0.434 0.0662 1.179 2.22 0.948 5.19 PRS_PLINK_0.0199526231496888 FALSE 208 Benign neoplasm of colon Both 2518 9791 2 neoplasms darkcyan 9791, 2518 2448, 680 2448, 668 2447, 593 2448, 576 -0.0424 0.0234 0.0708 1.15 0.959 0.915 1 0.0127 0.0631 0.84 0.0756 1.01 0.895 1.15 -0.115 0.0656 0.0797 1.098 0.891 0.784 1.01 -0.107 0.068 0.115 0.9398 0.898 0.786 1.03 PRS_PLINK_0.0199526231496888 FALSE 209 Neuroendocrine tumors Both 52 584 2 neoplasms darkcyan 584, 52 145, 18 146, 12 146, 14 146, 8 -0.185 0.134 0.168 0.7754 0.831 0.639 1.08 -0.427 0.375 0.254 0.5949 0.652 0.313 1.36 -0.314 0.366 0.39 0.4085 0.73 0.357 1.5 -0.847 0.427 0.0474 1.324 0.429 0.186 0.99 PRS_PLINK_0.0199526231496888 FALSE 210 Benign neoplasm of lip, oral cavity, and pharynx Both 432 4954 2 neoplasms darkcyan 4954, 432 1238, 102 1238, 103 1238, 114 1239, 113 0.0238 0.0517 0.646 0.1901 1.02 0.925 1.13 0.0121 0.145 0.934 0.02987 1.01 0.761 1.35 0.0889 0.144 0.537 0.2704 1.09 0.824 1.45 0.114 0.149 0.445 0.3516 1.12 0.837 1.5 PRS_PLINK_0.0199526231496888 FALSE 211 Benign neoplasm of other parts of digestive system Both 2061 10051 2 neoplasms darkcyan 10051, 2061 2513, 480 2513, 538 2512, 498 2513, 544 0.0603 0.025 0.0157 1.804 1.06 1.01 1.12 0.125 0.0694 0.0717 1.145 1.13 0.989 1.3 0.0606 0.0714 0.396 0.4022 1.06 0.924 1.22 0.129 0.0724 0.0752 1.124 1.14 0.987 1.31 PRS_PLINK_0.0199526231496888 FALSE 212 Benign neoplasm of respiratory and intrathoracic organs Both 480 4540 2 neoplasms darkcyan 4540, 480 1135, 117 1135, 120 1135, 123 1135, 120 0.0194 0.0493 0.695 0.1583 1.02 0.926 1.12 0.0457 0.137 0.738 0.132 1.05 0.801 1.37 0.0245 0.138 0.859 0.06601 1.02 0.782 1.34 0.0101 0.142 0.943 0.02547 1.01 0.765 1.33 PRS_PLINK_0.0199526231496888 FALSE 213 Benign neoplasm of bone and articular cartilage Both 464 4459 2 neoplasms darkcyan 4459, 464 1115, 123 1115, 104 1114, 117 1115, 120 0.0392 0.0497 0.43 0.366 1.04 0.943 1.15 -0.146 0.139 0.294 0.531 0.864 0.657 1.14 -0.0082 0.138 0.953 0.02113 0.992 0.757 1.3 -0.0195 0.14 0.889 0.05093 0.981 0.745 1.29 PRS_PLINK_0.0199526231496888 FALSE 214 Lipoma Both 364 3749 2 neoplasms darkcyan 3749, 364 938, 107 937, 83 937, 85 937, 89 -0.0688 0.0567 0.225 0.6478 0.934 0.835 1.04 -0.242 0.153 0.114 0.9423 0.785 0.582 1.06 -0.203 0.154 0.189 0.724 0.816 0.603 1.1 -0.165 0.157 0.291 0.5356 0.848 0.624 1.15 PRS_PLINK_0.0199526231496888 FALSE 214.1 Lipoma of skin and subcutaneous tissue Both 223 2368 2 neoplasms darkcyan 2368, 223 592, 52 592, 56 592, 51 592, 64 0.05 0.0741 0.5 0.3011 1.05 0.909 1.22 0.0791 0.2 0.693 0.1593 1.08 0.731 1.6 0.0129 0.209 0.951 0.02191 1.01 0.673 1.53 0.229 0.205 0.264 0.579 1.26 0.842 1.88 PRS_PLINK_0.0199526231496888 FALSE 215 Other benign neoplasm of connective and other soft tissue Both 1191 10735 2 neoplasms darkcyan 10735, 1191 2684, 298 2684, 288 2683, 297 2684, 307 0.0395 0.0313 0.207 0.6838 1.04 0.978 1.11 -0.00244 0.0875 0.978 0.009766 0.998 0.84 1.18 0.0404 0.088 0.646 0.1897 1.04 0.876 1.24 0.114 0.0901 0.207 0.6846 1.12 0.939 1.34 PRS_PLINK_0.0199526231496888 FALSE 216 Benign neoplasm of skin Both 3057 9668 2 neoplasms darkcyan 9668, 3057 2416, 805 2417, 776 2417, 776 2417, 700 -0.0344 0.0216 0.111 0.9555 0.966 0.926 1.01 -0.0111 0.0588 0.85 0.07037 0.989 0.881 1.11 -0.0158 0.0597 0.792 0.1015 0.984 0.876 1.11 -0.0945 0.0626 0.131 0.8818 0.91 0.805 1.03 PRS_PLINK_0.0199526231496888 FALSE 216.1 Screening for malignant neoplasms of the skin Both 57 483 2 neoplasms darkcyan 483, 57 121, 15 121, 10 120, 13 121, 19 0.159 0.15 0.289 0.5392 1.17 0.874 1.57 -0.36 0.412 0.382 0.4176 0.697 0.311 1.57 -0.189 0.407 0.643 0.192 0.828 0.373 1.84 0.356 0.404 0.378 0.422 1.43 0.647 3.15 PRS_PLINK_0.0199526231496888 FALSE 217 Vascular hamartomas and non-neoplastic nevi Both 461 4206 2 neoplasms darkcyan 4206, 461 1052, 128 1051, 115 1051, 121 1052, 97 -0.11 0.0505 0.0296 1.529 0.896 0.812 0.989 -0.14 0.136 0.304 0.5165 0.869 0.666 1.14 -0.103 0.136 0.449 0.3476 0.902 0.69 1.18 -0.301 0.147 0.0411 1.386 0.74 0.555 0.988 PRS_PLINK_0.0199526231496888 FALSE 217.1 Nevus, non-neoplastic Both 423 3867 2 neoplasms darkcyan 3867, 423 967, 119 967, 105 966, 111 967, 88 -0.122 0.0529 0.021 1.678 0.885 0.798 0.982 -0.154 0.142 0.278 0.5561 0.857 0.649 1.13 -0.122 0.142 0.392 0.4063 0.885 0.67 1.17 -0.323 0.154 0.0357 1.447 0.724 0.535 0.979 PRS_PLINK_0.0199526231496888 FALSE 218 Benign neoplasm of uterus Female 1573 5737 2 neoplasms darkcyan 5737, 1573 1434, 404 1434, 399 1434, 372 1434, 398 0.0126 0.0296 0.671 0.1732 1.01 0.956 1.07 0.000428 0.0806 0.996 0.001844 1 0.854 1.17 -0.0686 0.0829 0.408 0.3893 0.934 0.794 1.1 0.033 0.0841 0.695 0.1581 1.03 0.877 1.22 PRS_PLINK_0.0199526231496888 FALSE 218.1 Uterine leiomyoma Female 598 5233 2 neoplasms darkcyan 5233, 598 1308, 160 1308, 163 1308, 130 1308, 145 -0.0201 0.0449 0.654 0.1843 0.98 0.898 1.07 0.0396 0.119 0.739 0.1315 1.04 0.824 1.31 -0.197 0.127 0.121 0.9167 0.821 0.64 1.05 -0.0364 0.127 0.774 0.1112 0.964 0.752 1.24 PRS_PLINK_0.0199526231496888 FALSE 218.2 Other benign neoplasm of uterus Female 1302 5661 2 neoplasms darkcyan 5661, 1302 1415, 334 1415, 325 1415, 305 1415, 338 0.0112 0.0319 0.726 0.1393 1.01 0.95 1.08 -0.0233 0.087 0.789 0.1029 0.977 0.824 1.16 -0.0878 0.0896 0.327 0.4853 0.916 0.768 1.09 0.0303 0.0898 0.736 0.1331 1.03 0.864 1.23 PRS_PLINK_0.0199526231496888 FALSE 220 Benign neoplasm of ovary Female 333 3027 2 neoplasms darkcyan 3027, 333 756, 62 757, 97 756, 76 757, 98 0.117 0.0604 0.0533 1.273 1.12 0.998 1.27 0.457 0.17 0.00735 2.134 1.58 1.13 2.2 0.23 0.182 0.206 0.687 1.26 0.882 1.8 0.525 0.178 0.00317 2.499 1.69 1.19 2.4 PRS_PLINK_0.0199526231496888 FALSE 221 Benign neoplasm of other female genital organs Female 824 4996 2 neoplasms darkcyan 4996, 824 1248, 188 1249, 225 1249, 181 1249, 230 0.0477 0.0391 0.222 0.6533 1.05 0.972 1.13 0.19 0.107 0.0762 1.118 1.21 0.98 1.49 -0.0196 0.114 0.863 0.06381 0.981 0.785 1.23 0.223 0.112 0.0456 1.342 1.25 1 1.56 PRS_PLINK_0.0199526231496888 FALSE 222 Benign neoplasm of male genital organs Male 172 1980 2 neoplasms darkcyan 1980, 172 495, 46 495, 42 495, 42 495, 42 0.00327 0.0786 0.967 0.01464 1 0.86 1.17 -0.0626 0.22 0.776 0.11 0.939 0.61 1.45 -0.0771 0.223 0.729 0.1373 0.926 0.599 1.43 -0.0625 0.228 0.784 0.1056 0.939 0.601 1.47 PRS_PLINK_0.0199526231496888 FALSE 223 Benign neoplasm of kidney and other urinary organs Both 385 3388 2 neoplasms darkcyan 3388, 385 847, 98 847, 100 847, 92 847, 95 0.0373 0.0545 0.493 0.3072 1.04 0.933 1.15 0.0145 0.151 0.923 0.03466 1.01 0.755 1.36 -0.0754 0.155 0.626 0.2036 0.927 0.685 1.26 -0.0119 0.157 0.94 0.02697 0.988 0.726 1.34 PRS_PLINK_0.0199526231496888 FALSE 224 Benign neoplasm of eye Both 138 1443 2 neoplasms darkcyan 1443, 138 360, 29 361, 42 360, 31 361, 36 0.0157 0.0949 0.869 0.06116 1.02 0.843 1.22 0.293 0.251 0.243 0.6144 1.34 0.82 2.19 0.0794 0.268 0.767 0.1152 1.08 0.64 1.83 0.165 0.269 0.539 0.2685 1.18 0.696 2 PRS_PLINK_0.0199526231496888 FALSE 224.1 Benign neoplasm of eye, uveal Both 113 1157 2 neoplasms darkcyan 1157, 113 290, 22 289, 32 289, 29 289, 30 0.057 0.106 0.592 0.2277 1.06 0.859 1.3 0.265 0.285 0.352 0.454 1.3 0.746 2.28 0.239 0.29 0.41 0.3872 1.27 0.72 2.24 0.298 0.298 0.316 0.5003 1.35 0.752 2.41 PRS_PLINK_0.0199526231496888 FALSE 225 Benign neoplasm of brain and other parts of nervous system Both 287 3234 2 neoplasms darkcyan 3234, 287 809, 72 808, 56 808, 81 809, 78 0.104 0.0639 0.103 0.9874 1.11 0.979 1.26 -0.2 0.184 0.279 0.5546 0.819 0.571 1.18 0.17 0.172 0.322 0.4928 1.19 0.847 1.66 0.169 0.18 0.347 0.4601 1.18 0.832 1.69 PRS_PLINK_0.0199526231496888 FALSE 225.1 Benign neoplasm of brain, cranial nerves, meninges Both 204 2517 2 neoplasms darkcyan 2517, 204 630, 53 629, 33 629, 64 629, 54 0.139 0.0761 0.0677 1.169 1.15 0.99 1.33 -0.413 0.227 0.069 1.161 0.662 0.424 1.03 0.225 0.196 0.251 0.6001 1.25 0.853 1.84 0.102 0.211 0.628 0.2021 1.11 0.732 1.68 PRS_PLINK_0.0199526231496888 FALSE 225.2 Benign neoplasm of spinal cord, meninges Both 88 798 2 neoplasms darkcyan 798, 88 200, 22 199, 17 199, 19 200, 30 0.136 0.113 0.229 0.6399 1.15 0.918 1.43 -0.173 0.329 0.599 0.2229 0.841 0.442 1.6 -0.103 0.323 0.75 0.1247 0.902 0.479 1.7 0.338 0.306 0.27 0.568 1.4 0.769 2.55 PRS_PLINK_0.0199526231496888 FALSE 226 Benign neoplasm of thyroid glands Both 240 3889 2 neoplasms darkcyan 3889, 240 972, 54 972, 58 972, 59 972, 69 0.0942 0.0687 0.17 0.7683 1.1 0.96 1.26 0.0447 0.193 0.817 0.08792 1.05 0.716 1.53 0.0756 0.194 0.697 0.1567 1.08 0.737 1.58 0.28 0.196 0.153 0.8141 1.32 0.901 1.94 PRS_PLINK_0.0199526231496888 FALSE 227 Benign neoplasm of other endocrine glands and related structures Both 275 4589 2 neoplasms darkcyan 4589, 275 1148, 72 1147, 70 1147, 69 1147, 64 -0.0511 0.0633 0.42 0.3772 0.95 0.839 1.08 -0.0257 0.173 0.882 0.05469 0.975 0.695 1.37 -0.0327 0.175 0.852 0.06944 0.968 0.686 1.36 -0.103 0.183 0.572 0.2426 0.902 0.63 1.29 PRS_PLINK_0.0199526231496888 FALSE 227.1 Benign neoplasm of adrenal gland Both 105 1199 2 neoplasms darkcyan 1199, 105 300, 24 300, 30 299, 30 300, 21 -0.106 0.103 0.305 0.5161 0.899 0.734 1.1 0.205 0.282 0.468 0.3298 1.23 0.706 2.13 0.239 0.286 0.403 0.3946 1.27 0.725 2.22 -0.155 0.317 0.623 0.2053 0.856 0.46 1.59 PRS_PLINK_0.0199526231496888 FALSE 227.2 Benign neoplasm of parathyroid gland Both 86 2153 2 neoplasms darkcyan 2153, 86 539, 23 538, 25 538, 18 538, 20 -0.0578 0.113 0.609 0.2152 0.944 0.756 1.18 0.019 0.288 0.947 0.02347 1.02 0.579 1.79 -0.282 0.314 0.369 0.4333 0.754 0.408 1.39 -0.168 0.312 0.591 0.2282 0.846 0.458 1.56 PRS_PLINK_0.0199526231496888 FALSE 227.3 Benign neoplasm of pituitary gland and craniopharyngeal duct (pouch) Both 82 1215 2 neoplasms darkcyan 1215, 82 304, 26 304, 12 303, 21 304, 23 0.011 0.116 0.924 0.03437 1.01 0.806 1.27 -0.735 0.351 0.0362 1.442 0.48 0.241 0.954 -0.199 0.307 0.516 0.287 0.819 0.448 1.5 -0.00122 0.314 0.997 0.001353 0.999 0.54 1.85 PRS_PLINK_0.0199526231496888 FALSE 228 Hemangioma and lymphangioma, any site Both 537 5072 2 neoplasms darkcyan 5072, 537 1268, 148 1268, 123 1268, 142 1268, 124 -0.0585 0.0459 0.203 0.6934 0.943 0.862 1.03 -0.184 0.128 0.152 0.8182 0.832 0.648 1.07 -0.0837 0.125 0.505 0.2967 0.92 0.719 1.18 -0.259 0.133 0.051 1.292 0.771 0.594 1 PRS_PLINK_0.0199526231496888 FALSE 228.1 Hemangioma of skin and subcutaneous tissue Both 317 3060 2 neoplasms darkcyan 3060, 317 765, 81 765, 80 765, 83 765, 73 -0.0661 0.0589 0.262 0.5811 0.936 0.834 1.05 -0.018 0.165 0.913 0.03954 0.982 0.711 1.36 -0.0289 0.166 0.861 0.06476 0.971 0.702 1.34 -0.175 0.175 0.316 0.4999 0.839 0.596 1.18 PRS_PLINK_0.0199526231496888 FALSE 229 Benign neoplasm of unspecified sites Both 1762 10271 2 neoplasms darkcyan 10271, 1762 2568, 461 2568, 473 2567, 431 2568, 396 -0.0329 0.0266 0.217 0.6639 0.968 0.918 1.02 0.0394 0.0719 0.583 0.234 1.04 0.903 1.2 -0.0791 0.0744 0.287 0.5414 0.924 0.799 1.07 -0.129 0.0779 0.0985 1.006 0.879 0.755 1.02 PRS_PLINK_0.0199526231496888 FALSE 229.1 Benign neoplasm of lymph nodes Both 1206 9457 2 neoplasms darkcyan 9457, 1206 2365, 329 2364, 328 2364, 299 2364, 250 -0.0643 0.0316 0.0415 1.382 0.938 0.881 0.998 0.0174 0.084 0.836 0.07795 1.02 0.863 1.2 -0.113 0.0869 0.192 0.7164 0.893 0.753 1.06 -0.26 0.0931 0.0053 2.276 0.771 0.643 0.926 PRS_PLINK_0.0199526231496888 FALSE 240 Simple and unspecified goiter Both 286 3047 3 endocrine/metabolic brown 3047, 286 762, 66 762, 73 761, 75 762, 72 0.0279 0.0652 0.668 0.1749 1.03 0.905 1.17 0.0769 0.178 0.666 0.1766 1.08 0.762 1.53 0.176 0.182 0.335 0.4747 1.19 0.834 1.7 0.0316 0.188 0.866 0.06232 1.03 0.715 1.49 PRS_PLINK_0.0199526231496888 FALSE 241 Nontoxic nodular goiter Both 703 6763 3 endocrine/metabolic brown 6763, 703 1691, 165 1691, 191 1690, 172 1691, 175 0.0245 0.0414 0.554 0.2567 1.02 0.945 1.11 0.16 0.113 0.156 0.8063 1.17 0.941 1.46 0.0854 0.117 0.466 0.3315 1.09 0.866 1.37 0.0657 0.12 0.585 0.2327 1.07 0.843 1.35 PRS_PLINK_0.0199526231496888 FALSE 241.1 Nontoxic uninodular goiter Both 540 5890 3 endocrine/metabolic brown 5890, 540 1473, 129 1472, 146 1472, 130 1473, 135 0.00646 0.0468 0.89 0.05058 1.01 0.918 1.1 0.123 0.127 0.331 0.48 1.13 0.882 1.45 0.0347 0.132 0.793 0.1007 1.04 0.799 1.34 0.0373 0.135 0.782 0.1066 1.04 0.796 1.35 PRS_PLINK_0.0199526231496888 FALSE 241.2 Nontoxic multinodular goiter Both 257 3636 3 endocrine/metabolic brown 3636, 257 909, 62 909, 66 909, 53 909, 76 0.0772 0.0671 0.25 0.6024 1.08 0.947 1.23 0.0965 0.182 0.596 0.2246 1.1 0.771 1.57 -0.0685 0.196 0.726 0.1391 0.934 0.637 1.37 0.197 0.185 0.286 0.5438 1.22 0.848 1.75 PRS_PLINK_0.0199526231496888 FALSE 242 Thyrotoxicosis with or without goiter Both 358 3808 3 endocrine/metabolic brown 3808, 358 952, 86 952, 103 952, 70 952, 99 0.0283 0.0561 0.614 0.2121 1.03 0.922 1.15 0.194 0.153 0.206 0.6866 1.21 0.899 1.64 -0.172 0.169 0.309 0.5096 0.842 0.605 1.17 0.193 0.161 0.231 0.6362 1.21 0.885 1.66 PRS_PLINK_0.0199526231496888 FALSE 242.1 Graves' disease Both 144 1543 3 endocrine/metabolic brown 1543, 144 386, 32 386, 41 385, 31 386, 40 0.0615 0.0872 0.481 0.318 1.06 0.896 1.26 0.23 0.245 0.347 0.4591 1.26 0.779 2.04 -0.00698 0.26 0.979 0.009383 0.993 0.596 1.65 0.303 0.254 0.232 0.6349 1.35 0.824 2.23 PRS_PLINK_0.0199526231496888 FALSE 242.2 Toxic multinodular goiter Both 30 346 3 endocrine/metabolic brown 346, 30 87, 4 86, 12 86, 6 87, 8 0.0689 0.193 0.72 0.1424 1.07 0.735 1.56 1.09 0.546 0.0463 1.335 2.97 1.02 8.64 0.526 0.6 0.381 0.4195 1.69 0.522 5.48 0.428 0.621 0.491 0.3087 1.53 0.454 5.18 PRS_PLINK_0.0199526231496888 TRUE 242.3 Exophthalmos Both 59 798 3 endocrine/metabolic brown 798, 59 200, 9 199, 23 199, 15 200, 12 -0.0159 0.135 0.906 0.04274 0.984 0.756 1.28 0.833 0.381 0.029 1.538 2.3 1.09 4.86 0.465 0.413 0.26 0.5846 1.59 0.708 3.58 0.381 0.436 0.382 0.4174 1.46 0.622 3.44 PRS_PLINK_0.0199526231496888 FALSE 242.31 Thyrotoxic exophthalmos Both 28 432 3 endocrine/metabolic brown 432, 28 108, 8 108, 10 108, 7 108, 3 -0.267 0.19 0.159 0.799 0.765 0.528 1.11 0.0199 0.479 0.967 0.0146 1.02 0.399 2.61 -0.254 0.52 0.625 0.204 0.776 0.28 2.15 -0.561 0.623 0.368 0.4343 0.571 0.168 1.93 PRS_PLINK_0.0199526231496888 TRUE 244 Hypothyroidism Both 2135 9210 3 endocrine/metabolic brown 9210, 2135 2303, 501 2302, 544 2302, 536 2303, 553 0.0715 0.0255 0.005 2.301 1.07 1.02 1.13 0.116 0.0709 0.103 0.9878 1.12 0.977 1.29 0.11 0.0718 0.125 0.9041 1.12 0.97 1.29 0.191 0.0738 0.00973 2.012 1.21 1.05 1.4 PRS_PLINK_0.0199526231496888 FALSE 244.1 Secondary hypothyroidism Both 395 4994 3 endocrine/metabolic brown 4994, 395 1249, 79 1248, 99 1248, 96 1249, 121 0.154 0.054 0.00438 2.358 1.17 1.05 1.3 0.203 0.156 0.192 0.7177 1.23 0.903 1.66 0.205 0.16 0.2 0.7001 1.23 0.898 1.68 0.485 0.157 0.002 2.698 1.62 1.19 2.21 PRS_PLINK_0.0199526231496888 FALSE 244.2 Acquired hypothyroidism Both 399 3512 3 endocrine/metabolic brown 3512, 399 878, 84 878, 104 878, 100 878, 111 0.143 0.0542 0.00825 2.083 1.15 1.04 1.28 0.216 0.154 0.161 0.794 1.24 0.918 1.68 0.203 0.157 0.197 0.7059 1.23 0.9 1.67 0.355 0.159 0.0258 1.588 1.43 1.04 1.95 PRS_PLINK_0.0199526231496888 FALSE 244.4 Hypothyroidism NOS Both 2005 9099 3 endocrine/metabolic brown 9099, 2005 2275, 472 2275, 509 2274, 505 2275, 518 0.0718 0.0261 0.00603 2.22 1.07 1.02 1.13 0.113 0.073 0.123 0.9115 1.12 0.97 1.29 0.115 0.0737 0.119 0.9241 1.12 0.971 1.3 0.189 0.0758 0.0124 1.905 1.21 1.04 1.4 PRS_PLINK_0.0199526231496888 FALSE 245 Thyroiditis Both 265 2707 3 endocrine/metabolic brown 2707, 265 677, 58 677, 77 676, 65 677, 65 0.0752 0.0673 0.264 0.5788 1.08 0.945 1.23 0.285 0.182 0.117 0.9334 1.33 0.931 1.9 0.153 0.191 0.423 0.3734 1.17 0.801 1.69 0.165 0.198 0.403 0.3942 1.18 0.801 1.74 PRS_PLINK_0.0199526231496888 FALSE 245.2 Chronic thyroiditis Both 210 2268 3 endocrine/metabolic brown 2268, 210 567, 44 567, 60 567, 58 567, 48 0.0801 0.0754 0.288 0.5407 1.08 0.935 1.26 0.314 0.207 0.13 0.8851 1.37 0.912 2.05 0.328 0.213 0.124 0.907 1.39 0.914 2.11 0.176 0.229 0.443 0.3535 1.19 0.761 1.87 PRS_PLINK_0.0199526231496888 FALSE 245.21 Chronic lymphocytic thyroiditis Both 208 2257 3 endocrine/metabolic brown 2257, 208 565, 44 564, 60 564, 58 564, 46 0.0648 0.0757 0.392 0.4071 1.07 0.92 1.24 0.319 0.208 0.125 0.9028 1.38 0.915 2.07 0.331 0.214 0.122 0.9126 1.39 0.915 2.12 0.143 0.231 0.535 0.2719 1.15 0.734 1.81 PRS_PLINK_0.0199526231496888 FALSE 246 Other disorders of thyroid Both 1535 8519 3 endocrine/metabolic brown 8519, 1535 2130, 386 2130, 384 2129, 375 2130, 389 0.0296 0.0292 0.31 0.5086 1.03 0.973 1.09 0.036 0.0808 0.656 0.183 1.04 0.885 1.21 0.0203 0.0819 0.804 0.09476 1.02 0.869 1.2 0.126 0.0842 0.135 0.8701 1.13 0.962 1.34 PRS_PLINK_0.0199526231496888 FALSE 246.2 Thyroid cyst Both 27 245 3 endocrine/metabolic brown 245, 27 62, 4 61, 6 61, 10 61, 7 0.126 0.196 0.52 0.2837 1.13 0.773 1.66 0.454 0.595 0.445 0.3512 1.57 0.491 5.05 0.848 0.595 0.154 0.8135 2.34 0.728 7.49 0.274 0.625 0.661 0.1796 1.31 0.387 4.47 PRS_PLINK_0.0199526231496888 TRUE 246.7 Abnormal results of function study of thyroid Both 253 2521 3 endocrine/metabolic brown 2521, 253 631, 55 630, 57 630, 56 630, 84 0.102 0.0667 0.127 0.8967 1.11 0.972 1.26 0.0141 0.197 0.943 0.0255 1.01 0.69 1.49 0.0291 0.2 0.885 0.05325 1.03 0.695 1.52 0.492 0.192 0.0103 1.985 1.63 1.12 2.38 PRS_PLINK_0.0199526231496888 FALSE 249 Secondary diabetes mellitus Both 200 2060 3 endocrine/metabolic brown 2060, 200 515, 38 515, 47 515, 44 515, 71 0.264 0.0823 0.00134 2.874 1.3 1.11 1.53 0.116 0.238 0.626 0.2035 1.12 0.704 1.79 0.0149 0.246 0.952 0.02145 1.01 0.627 1.64 0.559 0.23 0.015 1.824 1.75 1.11 2.74 PRS_PLINK_0.0199526231496888 FALSE 250 Diabetes mellitus Both 2645 9884 3 endocrine/metabolic brown 9884, 2645 2470, 662 2471, 617 2471, 669 2471, 697 0.0837 0.0246 0.00066 3.18 1.09 1.04 1.14 -0.0587 0.069 0.395 0.4039 0.943 0.824 1.08 0.0583 0.0687 0.396 0.4024 1.06 0.927 1.21 0.192 0.0703 0.0062 2.208 1.21 1.06 1.39 PRS_PLINK_0.0199526231496888 FALSE 250.1 Type 1 diabetes Both 485 3068 3 endocrine/metabolic brown 3068, 485 767, 109 767, 114 767, 126 767, 136 0.129 0.0726 0.0749 1.125 1.14 0.987 1.31 -0.0732 0.211 0.728 0.1378 0.929 0.615 1.4 -0.0348 0.208 0.867 0.06199 0.966 0.643 1.45 0.301 0.198 0.128 0.8921 1.35 0.917 1.99 PRS_PLINK_0.0199526231496888 FALSE 250.11 Type 1 diabetes with ketoacidosis Both 90 317 3 endocrine/metabolic brown 317, 90 80, 20 79, 26 79, 20 79, 24 0.158 0.174 0.364 0.4384 1.17 0.832 1.65 0.167 0.473 0.725 0.1399 1.18 0.468 2.98 -0.0501 0.511 0.922 0.03531 0.951 0.349 2.59 -0.00358 0.475 0.994 0.002621 0.996 0.393 2.53 PRS_PLINK_0.0199526231496888 FALSE 250.12 Type 1 diabetes with renal manifestations Both 80 719 3 endocrine/metabolic brown 719, 80 180, 19 180, 14 179, 22 180, 25 0.179 0.15 0.233 0.6331 1.2 0.891 1.6 -0.0243 0.434 0.955 0.01982 0.976 0.417 2.28 -0.25 0.431 0.562 0.25 0.779 0.335 1.81 0.262 0.41 0.523 0.2814 1.3 0.582 2.9 PRS_PLINK_0.0199526231496888 FALSE 250.13 Type 1 diabetes with ophthalmic manifestations Both 133 813 3 endocrine/metabolic brown 813, 133 204, 30 203, 27 203, 45 203, 31 0.171 0.136 0.209 0.6792 1.19 0.909 1.55 -0.13 0.43 0.762 0.1181 0.878 0.378 2.04 0.297 0.37 0.421 0.3753 1.35 0.652 2.78 0.321 0.369 0.384 0.4157 1.38 0.669 2.84 PRS_PLINK_0.0199526231496888 FALSE 250.14 Type 1 diabetes with neurological manifestations Both 108 722 3 endocrine/metabolic brown 722, 108 181, 23 180, 21 180, 33 181, 31 0.25 0.143 0.0798 1.098 1.28 0.971 1.7 -0.626 0.449 0.163 0.7887 0.535 0.222 1.29 0.0151 0.385 0.969 0.01378 1.02 0.477 2.16 0.58 0.368 0.115 0.9378 1.79 0.868 3.68 PRS_PLINK_0.0199526231496888 FALSE 250.15 Diabetes type 1 with peripheral circulatory disorders Both 23 213 3 endocrine/metabolic brown 213, 23 54, 3 53, 6 53, 6 53, 8 0.928 0.335 0.00561 2.251 2.53 1.31 4.88 1.94 1.19 0.103 0.9877 6.94 0.677 71.2 1.57 1.03 0.125 0.9022 4.83 0.645 36.1 2.01 1.03 0.0511 1.291 7.5 0.99 56.8 PRS_PLINK_0.0199526231496888 TRUE 250.2 Type 2 diabetes Both 1705 8843 3 endocrine/metabolic brown 8843, 1705 2210, 408 2211, 392 2210, 428 2211, 477 0.134 0.0303 9.28e-06 5.032 1.14 1.08 1.21 -0.0538 0.0865 0.534 0.2722 0.948 0.8 1.12 0.0724 0.0859 0.399 0.3986 1.08 0.908 1.27 0.29 0.0862 0.000765 3.116 1.34 1.13 1.58 PRS_PLINK_0.0199526231496888 FALSE 250.21 Type 2 diabetes with ketoacidosis Both 77 388 3 endocrine/metabolic brown 388, 77 97, 11 97, 26 97, 17 97, 23 0.315 0.165 0.0557 1.254 1.37 0.992 1.89 0.734 0.485 0.13 0.8849 2.08 0.805 5.39 0.464 0.554 0.402 0.3956 1.59 0.537 4.71 0.608 0.494 0.218 0.6615 1.84 0.698 4.83 PRS_PLINK_0.0199526231496888 FALSE 250.22 Type 2 diabetes with renal manifestations Both 278 2907 3 endocrine/metabolic brown 2907, 278 727, 60 727, 63 726, 59 727, 96 0.244 0.0699 0.000484 3.315 1.28 1.11 1.46 0.00979 0.201 0.961 0.01723 1.01 0.681 1.5 -0.0859 0.209 0.681 0.1671 0.918 0.61 1.38 0.489 0.192 0.0111 1.956 1.63 1.12 2.38 PRS_PLINK_0.0199526231496888 FALSE 250.23 Type 2 diabetes with ophthalmic manifestations Both 199 2189 3 endocrine/metabolic brown 2189, 199 548, 48 547, 41 547, 52 547, 58 0.156 0.092 0.0893 1.049 1.17 0.976 1.4 -0.0327 0.265 0.902 0.04487 0.968 0.575 1.63 0.128 0.255 0.616 0.2103 1.14 0.69 1.87 0.302 0.26 0.245 0.6108 1.35 0.813 2.25 PRS_PLINK_0.0199526231496888 FALSE 250.24 Type 2 diabetes with neurological manifestations Both 363 3815 3 endocrine/metabolic brown 3815, 363 954, 69 954, 82 953, 83 954, 129 0.335 0.0643 1.83e-07 6.738 1.4 1.23 1.59 0.0849 0.194 0.661 0.1797 1.09 0.745 1.59 0.0501 0.194 0.796 0.09915 1.05 0.719 1.54 0.695 0.179 0.000105 3.98 2 1.41 2.85 PRS_PLINK_0.0199526231496888 FALSE 250.25 Diabetes type 2 with peripheral circulatory disorders Both 154 1220 3 endocrine/metabolic brown 1220, 154 305, 29 305, 32 305, 36 305, 57 0.325 0.0942 0.000554 3.257 1.38 1.15 1.67 0.145 0.284 0.61 0.2146 1.16 0.662 2.02 0.149 0.287 0.602 0.2201 1.16 0.662 2.04 0.703 0.278 0.0114 1.942 2.02 1.17 3.48 PRS_PLINK_0.0199526231496888 FALSE 250.3 Insulin pump user Both 622 5325 3 endocrine/metabolic brown 5325, 622 1331, 133 1331, 148 1331, 156 1331, 185 0.286 0.054 1.17e-07 6.932 1.33 1.2 1.48 0.135 0.161 0.399 0.3991 1.15 0.836 1.57 0.219 0.162 0.175 0.7563 1.25 0.907 1.71 0.618 0.155 6.56e-05 4.183 1.85 1.37 2.51 PRS_PLINK_0.0199526231496888 FALSE 250.4 Abnormal glucose Both 1679 9394 3 endocrine/metabolic brown 9394, 1679 2348, 424 2348, 399 2348, 432 2349, 424 0.0544 0.0301 0.0708 1.15 1.06 0.995 1.12 -0.0475 0.0838 0.571 0.2437 0.954 0.809 1.12 0.0624 0.083 0.453 0.3443 1.06 0.905 1.25 0.13 0.086 0.13 0.8852 1.14 0.962 1.35 PRS_PLINK_0.0199526231496888 FALSE 250.41 Impaired fasting glucose Both 366 4225 3 endocrine/metabolic brown 4225, 366 1056, 97 1056, 89 1056, 91 1056, 89 -0.0511 0.0583 0.38 0.42 0.95 0.848 1.07 -0.116 0.161 0.472 0.3259 0.891 0.65 1.22 -0.0463 0.158 0.77 0.1134 0.955 0.7 1.3 -0.0428 0.164 0.794 0.1001 0.958 0.695 1.32 PRS_PLINK_0.0199526231496888 FALSE 250.42 Other abnormal glucose Both 1486 9087 3 endocrine/metabolic brown 9087, 1486 2271, 375 2272, 346 2271, 378 2272, 387 0.0623 0.0319 0.0511 1.291 1.06 1 1.13 -0.0525 0.0891 0.556 0.2552 0.949 0.797 1.13 0.0221 0.0887 0.804 0.09493 1.02 0.859 1.22 0.15 0.0908 0.0977 1.01 1.16 0.973 1.39 PRS_PLINK_0.0199526231496888 FALSE 250.5 Glycosuria or Acetonuria Both 34 340 3 endocrine/metabolic brown 340, 34 85, 5 85, 11 85, 9 85, 9 0.088 0.198 0.656 0.1828 1.09 0.741 1.61 0.265 0.547 0.628 0.2023 1.3 0.447 3.81 0.221 0.563 0.694 0.1583 1.25 0.414 3.76 0.281 0.561 0.616 0.2102 1.32 0.441 3.98 PRS_PLINK_0.0199526231496888 TRUE 250.6 Polyneuropathy in diabetes Both 301 3020 3 endocrine/metabolic brown 3020, 301 755, 59 755, 65 755, 78 755, 99 0.278 0.0743 0.000183 3.737 1.32 1.14 1.53 -0.0405 0.219 0.853 0.06883 0.96 0.625 1.48 0.0601 0.211 0.776 0.1102 1.06 0.702 1.61 0.499 0.204 0.0146 1.837 1.65 1.1 2.46 PRS_PLINK_0.0199526231496888 FALSE 250.7 Diabetic retinopathy Both 229 2363 3 endocrine/metabolic brown 2363, 229 591, 61 591, 43 590, 68 591, 57 0.063 0.077 0.413 0.3839 1.07 0.916 1.24 -0.449 0.225 0.0457 1.34 0.639 0.411 0.992 0.097 0.203 0.633 0.1985 1.1 0.74 1.64 -0.0708 0.216 0.743 0.1289 0.932 0.61 1.42 PRS_PLINK_0.0199526231496888 FALSE 251 Other disorders of pancreatic internal secretion Both 312 2373 3 endocrine/metabolic brown 2373, 312 594, 76 593, 71 593, 79 593, 86 0.0822 0.0624 0.188 0.7268 1.09 0.961 1.23 -0.074 0.178 0.678 0.169 0.929 0.655 1.32 0.0661 0.176 0.707 0.1503 1.07 0.756 1.51 0.156 0.178 0.378 0.422 1.17 0.826 1.66 PRS_PLINK_0.0199526231496888 FALSE 251.1 Hypoglycemia Both 375 2682 3 endocrine/metabolic brown 2682, 375 671, 90 670, 93 670, 88 671, 104 0.105 0.0617 0.0899 1.046 1.11 0.984 1.25 0.118 0.175 0.5 0.3014 1.13 0.798 1.59 0.116 0.179 0.516 0.2875 1.12 0.791 1.6 0.311 0.177 0.0793 1.101 1.37 0.964 1.93 PRS_PLINK_0.0199526231496888 FALSE 252 Disorders of parathyroid gland Both 350 5844 3 endocrine/metabolic brown 5844, 350 1461, 80 1461, 79 1461, 76 1461, 114 0.11 0.0562 0.0508 1.294 1.12 1 1.25 -0.0162 0.162 0.92 0.0361 0.984 0.716 1.35 -0.0654 0.166 0.694 0.1588 0.937 0.676 1.3 0.364 0.156 0.0198 1.704 1.44 1.06 1.96 PRS_PLINK_0.0199526231496888 FALSE 252.1 Hyperparathyroidism Both 305 5239 3 endocrine/metabolic brown 5239, 305 1310, 69 1310, 71 1309, 67 1310, 97 0.117 0.0604 0.0519 1.285 1.12 0.999 1.27 0.0239 0.172 0.89 0.05073 1.02 0.731 1.44 -0.0357 0.177 0.84 0.07559 0.965 0.682 1.37 0.332 0.168 0.0483 1.316 1.39 1 1.94 PRS_PLINK_0.0199526231496888 FALSE 252.2 Hypoparathyroidism Both 79 1372 3 endocrine/metabolic brown 1372, 79 343, 25 343, 14 343, 18 343, 22 0.00676 0.118 0.954 0.02033 1.01 0.799 1.27 -0.524 0.331 0.113 0.9451 0.592 0.309 1.13 -0.245 0.315 0.438 0.3586 0.783 0.422 1.45 -0.0707 0.315 0.823 0.08484 0.932 0.502 1.73 PRS_PLINK_0.0199526231496888 FALSE 253 Disorders of the pituitary gland and its hypothalamic control Both 225 2387 3 endocrine/metabolic brown 2387, 225 597, 56 597, 52 596, 49 597, 68 0.0989 0.0693 0.154 0.8129 1.1 0.964 1.26 -0.0938 0.199 0.638 0.1952 0.91 0.616 1.35 -0.139 0.205 0.499 0.302 0.871 0.582 1.3 0.147 0.195 0.449 0.3481 1.16 0.791 1.7 PRS_PLINK_0.0199526231496888 FALSE 253.1 Pituitary hyperfunction Both 74 845 3 endocrine/metabolic brown 845, 74 212, 16 211, 17 211, 18 211, 23 0.147 0.124 0.234 0.6302 1.16 0.909 1.48 0.133 0.354 0.707 0.1508 1.14 0.571 2.29 0.224 0.35 0.523 0.2812 1.25 0.629 2.49 0.364 0.354 0.304 0.5174 1.44 0.719 2.88 PRS_PLINK_0.0199526231496888 FALSE 253.11 Acromegaly and gigantism Both 12 216 3 endocrine/metabolic brown 216, 12 54, 3 54, 2 54, 3 54, 4 0.117 0.281 0.676 0.1699 1.12 0.649 1.95 -0.283 0.851 0.74 0.1311 0.754 0.142 3.99 -0.00289 0.715 0.997 0.001403 0.997 0.246 4.05 0.14 0.748 0.851 0.07007 1.15 0.266 4.98 PRS_PLINK_0.0199526231496888 TRUE 253.2 Pituitary hypofunction Both 50 602 3 endocrine/metabolic brown 602, 50 151, 13 150, 11 150, 10 151, 16 0.135 0.147 0.358 0.446 1.14 0.858 1.53 -0.136 0.401 0.735 0.1338 0.873 0.397 1.92 -0.195 0.415 0.639 0.1945 0.823 0.365 1.86 0.0227 0.396 0.954 0.02029 1.02 0.471 2.22 PRS_PLINK_0.0199526231496888 TRUE 253.3 Diabetes insipidus Both 15 247 3 endocrine/metabolic brown 247, 15 62, 2 62, 4 61, 2 62, 7 0.591 0.227 0.00921 2.036 1.81 1.16 2.82 0.447 0.722 0.536 0.2708 1.56 0.38 6.43 -0.593 1.04 0.568 0.246 0.553 0.0725 4.22 0.907 0.725 0.211 0.6764 2.48 0.599 10.2 PRS_PLINK_0.0199526231496888 TRUE 253.4 Anterior pituitary disorders Both 28 277 3 endocrine/metabolic brown 277, 28 70, 5 69, 11 69, 3 69, 9 0.101 0.196 0.607 0.2172 1.11 0.753 1.63 0.72 0.531 0.175 0.7574 2.06 0.726 5.82 -0.513 0.694 0.46 0.3376 0.599 0.154 2.33 0.297 0.571 0.603 0.2196 1.35 0.44 4.12 PRS_PLINK_0.0199526231496888 TRUE 253.7 Other disorders of neurohypophysis Both 25 246 3 endocrine/metabolic brown 246, 25 62, 3 61, 4 61, 11 62, 7 0.177 0.209 0.398 0.4004 1.19 0.792 1.8 0.163 0.666 0.807 0.09324 1.18 0.319 4.34 1.07 0.609 0.0781 1.108 2.93 0.886 9.66 0.808 0.68 0.235 0.6292 2.24 0.591 8.51 PRS_PLINK_0.0199526231496888 TRUE 255 Disorders of adrenal glands Both 394 4078 3 endocrine/metabolic brown 4078, 394 1020, 95 1019, 108 1019, 83 1020, 107 0.00122 0.0538 0.982 0.007911 1 0.901 1.11 0.104 0.147 0.479 0.3198 1.11 0.832 1.48 -0.161 0.158 0.31 0.5085 0.852 0.625 1.16 0.0353 0.154 0.818 0.08726 1.04 0.767 1.4 PRS_PLINK_0.0199526231496888 FALSE 255.1 Adrenal hyperfunction Both 74 1198 3 endocrine/metabolic brown 1198, 74 300, 17 299, 19 299, 17 300, 21 0.0475 0.124 0.702 0.154 1.05 0.823 1.34 0.192 0.332 0.563 0.2494 1.21 0.632 2.32 0.0215 0.342 0.95 0.02238 1.02 0.523 2 0.0589 0.339 0.862 0.06457 1.06 0.546 2.06 PRS_PLINK_0.0199526231496888 FALSE 255.11 Cushing's syndrome Both 42 659 3 endocrine/metabolic brown 659, 42 165, 11 165, 13 164, 7 165, 11 0.00644 0.16 0.968 0.01414 1.01 0.735 1.38 0.306 0.419 0.466 0.3317 1.36 0.597 3.09 -0.142 0.463 0.759 0.12 0.867 0.35 2.15 -0.0296 0.431 0.945 0.02452 0.971 0.417 2.26 PRS_PLINK_0.0199526231496888 TRUE 255.12 Hyperaldosteronism Both 16 327 3 endocrine/metabolic brown 327, 16 82, 4 82, 5 81, 3 82, 4 -0.0473 0.24 0.844 0.07367 0.954 0.595 1.53 0.066 0.616 0.915 0.03874 1.07 0.319 3.57 -0.0256 0.69 0.97 0.01306 0.975 0.252 3.77 -0.119 0.716 0.868 0.06157 0.888 0.218 3.61 PRS_PLINK_0.0199526231496888 TRUE 255.2 Adrenal hypofunction Both 195 1814 3 endocrine/metabolic brown 1814, 195 454, 43 453, 52 453, 34 454, 65 0.121 0.076 0.11 0.9594 1.13 0.973 1.31 0.192 0.214 0.369 0.4326 1.21 0.797 1.84 -0.168 0.239 0.483 0.3164 0.845 0.529 1.35 0.381 0.214 0.0744 1.128 1.46 0.963 2.22 PRS_PLINK_0.0199526231496888 FALSE 255.21 Glucocorticoid deficiency Both 184 1744 3 endocrine/metabolic brown 1744, 184 436, 40 436, 47 436, 36 436, 60 0.133 0.0785 0.0908 1.042 1.14 0.979 1.33 0.169 0.222 0.447 0.3496 1.18 0.766 1.83 -0.0255 0.24 0.915 0.03847 0.975 0.61 1.56 0.377 0.223 0.091 1.041 1.46 0.942 2.26 PRS_PLINK_0.0199526231496888 FALSE 256 Ovarian dysfunction Female 445 4842 3 endocrine/metabolic brown 4842, 445 1211, 118 1210, 104 1210, 133 1211, 90 -0.00412 0.052 0.937 0.02834 0.996 0.899 1.1 -0.118 0.14 0.401 0.3967 0.889 0.675 1.17 0.202 0.135 0.135 0.8686 1.22 0.939 1.59 -0.206 0.151 0.173 0.7623 0.814 0.605 1.09 PRS_PLINK_0.0199526231496888 FALSE 256.4 Polycystic ovaries Female 276 3570 3 endocrine/metabolic brown 3570, 276 893, 76 892, 59 892, 79 893, 62 0.0381 0.0653 0.559 0.2523 1.04 0.914 1.18 -0.24 0.178 0.178 0.7495 0.786 0.554 1.12 0.112 0.169 0.508 0.294 1.12 0.803 1.56 -0.147 0.183 0.422 0.3749 0.863 0.603 1.24 PRS_PLINK_0.0199526231496888 FALSE 257 Testicular dysfunction Male 186 1704 3 endocrine/metabolic brown 1704, 186 426, 52 426, 43 426, 42 426, 49 -0.0252 0.0799 0.752 0.1236 0.975 0.834 1.14 -0.214 0.218 0.327 0.4857 0.807 0.527 1.24 -0.266 0.225 0.237 0.6262 0.766 0.493 1.19 -0.082 0.228 0.719 0.1434 0.921 0.589 1.44 PRS_PLINK_0.0199526231496888 FALSE 257.1 Testicular hypofunction Male 178 1633 3 endocrine/metabolic brown 1633, 178 409, 49 408, 41 408, 41 408, 47 -0.0195 0.082 0.812 0.09041 0.981 0.835 1.15 -0.187 0.224 0.402 0.3955 0.829 0.535 1.29 -0.222 0.229 0.331 0.4796 0.801 0.511 1.25 -0.0106 0.235 0.964 0.0159 0.989 0.625 1.57 PRS_PLINK_0.0199526231496888 FALSE 258 Iatrogenic endocrine disorders Both 17 219 3 endocrine/metabolic brown 219, 17 55, 4 55, 3 54, 5 55, 5 0.292 0.24 0.224 0.65 1.34 0.837 2.14 -0.0731 0.69 0.916 0.03828 0.929 0.24 3.6 0.431 0.639 0.5 0.3011 1.54 0.44 5.39 0.424 0.653 0.516 0.2871 1.53 0.425 5.49 PRS_PLINK_0.0199526231496888 TRUE 258.1 Postablative ovarian failure Female 50 463 3 endocrine/metabolic brown 463, 50 116, 8 116, 14 115, 11 116, 17 0.224 0.157 0.154 0.8128 1.25 0.92 1.7 0.586 0.448 0.191 0.7194 1.8 0.747 4.33 0.377 0.467 0.42 0.3772 1.46 0.584 3.64 0.553 0.451 0.22 0.6575 1.74 0.718 4.21 PRS_PLINK_0.0199526231496888 TRUE 259 Other endocrine disorders Both 274 3112 3 endocrine/metabolic brown 3112, 274 778, 70 778, 66 778, 70 778, 68 0.0433 0.066 0.512 0.291 1.04 0.918 1.19 -0.038 0.178 0.831 0.08021 0.963 0.679 1.37 0.0349 0.18 0.846 0.07278 1.04 0.728 1.47 -0.0617 0.185 0.738 0.1319 0.94 0.655 1.35 PRS_PLINK_0.0199526231496888 FALSE 260 Protein-calorie malnutrition Both 1057 6262 3 endocrine/metabolic brown 6262, 1057 1566, 221 1565, 256 1565, 292 1566, 287 0.134 0.034 8.39e-05 4.076 1.14 1.07 1.22 0.158 0.0991 0.112 0.9517 1.17 0.964 1.42 0.295 0.0982 0.00263 2.58 1.34 1.11 1.63 0.319 0.101 0.00155 2.809 1.38 1.13 1.68 PRS_PLINK_0.0199526231496888 FALSE 260.1 Cachexia Both 148 596 3 endocrine/metabolic brown 596, 148 149, 35 149, 29 149, 43 149, 41 0.105 0.0919 0.251 0.5998 1.11 0.928 1.33 -0.176 0.276 0.524 0.2805 0.839 0.488 1.44 0.239 0.262 0.361 0.4419 1.27 0.76 2.12 0.169 0.264 0.523 0.2817 1.18 0.706 1.98 PRS_PLINK_0.0199526231496888 FALSE 260.2 severe protein-calorie malnutrition Both 666 3739 3 endocrine/metabolic brown 3739, 666 935, 139 935, 179 934, 171 935, 176 0.0994 0.0429 0.0205 1.688 1.1 1.02 1.2 0.262 0.123 0.0323 1.49 1.3 1.02 1.65 0.23 0.126 0.0679 1.168 1.26 0.983 1.61 0.298 0.128 0.0195 1.71 1.35 1.05 1.73 PRS_PLINK_0.0199526231496888 FALSE 260.22 Nutritional marasmus Both 232 1413 3 endocrine/metabolic brown 1413, 232 354, 50 353, 55 353, 61 353, 65 0.177 0.0726 0.0149 1.827 1.19 1.04 1.38 0.12 0.21 0.569 0.2453 1.13 0.747 1.7 0.146 0.207 0.48 0.3185 1.16 0.771 1.74 0.289 0.211 0.17 0.769 1.33 0.883 2.02 PRS_PLINK_0.0199526231496888 FALSE 260.3 Adult failure to thrive Both 223 1252 3 endocrine/metabolic brown 1252, 223 313, 57 313, 34 313, 58 313, 73 0.15 0.0744 0.0436 1.36 1.16 1 1.34 -0.492 0.232 0.0343 1.465 0.611 0.388 0.964 0.0714 0.209 0.733 0.1349 1.07 0.713 1.62 0.237 0.201 0.238 0.6226 1.27 0.855 1.88 PRS_PLINK_0.0199526231496888 FALSE 260.6 Anorexia Both 299 2003 3 endocrine/metabolic brown 2003, 299 501, 84 501, 74 500, 67 501, 74 -0.0194 0.064 0.762 0.1181 0.981 0.865 1.11 -0.137 0.172 0.426 0.3704 0.872 0.623 1.22 -0.2 0.178 0.262 0.581 0.819 0.578 1.16 -0.14 0.183 0.443 0.3533 0.869 0.608 1.24 PRS_PLINK_0.0199526231496888 FALSE 260.7 Polyphagia Both 22 252 3 endocrine/metabolic brown 252, 22 63, 9 63, 7 63, 4 63, 2 -0.522 0.223 0.0193 1.716 0.593 0.383 0.919 -0.12 0.511 0.815 0.08903 0.887 0.326 2.42 -0.606 0.576 0.293 0.5329 0.546 0.176 1.69 -1.33 0.702 0.0582 1.235 0.264 0.0667 1.05 PRS_PLINK_0.0199526231496888 TRUE 261 Vitamin deficiency Both 2033 9510 3 endocrine/metabolic brown 9510, 2033 2378, 521 2377, 510 2377, 480 2378, 521 0.0325 0.0256 0.204 0.6914 1.03 0.983 1.09 0.00857 0.0704 0.903 0.04428 1.01 0.879 1.16 -0.0413 0.0722 0.568 0.2459 0.96 0.833 1.11 0.0847 0.0732 0.247 0.6065 1.09 0.943 1.26 PRS_PLINK_0.0199526231496888 FALSE 261.1 Vitamin A deficiency Both 32 244 3 endocrine/metabolic brown 244, 32 61, 9 61, 5 61, 5 61, 13 0.174 0.187 0.352 0.4531 1.19 0.825 1.72 -0.403 0.551 0.465 0.3324 0.668 0.227 1.97 -0.469 0.578 0.417 0.3795 0.626 0.202 1.94 0.217 0.485 0.655 0.1837 1.24 0.48 3.22 PRS_PLINK_0.0199526231496888 TRUE 261.2 Vitamin B-complex deficiencies Both 236 2212 3 endocrine/metabolic brown 2212, 236 553, 55 553, 54 553, 53 553, 74 0.129 0.0705 0.0675 1.171 1.14 0.991 1.31 -0.00558 0.199 0.978 0.009816 0.994 0.673 1.47 -0.0545 0.203 0.788 0.1033 0.947 0.636 1.41 0.33 0.194 0.0901 1.045 1.39 0.95 2.04 PRS_PLINK_0.0199526231496888 FALSE 261.4 Vitamin D deficiency Both 1910 9518 3 endocrine/metabolic brown 9518, 1910 2380, 486 2379, 488 2379, 455 2380, 480 0.0262 0.0263 0.319 0.4958 1.03 0.975 1.08 0.0319 0.072 0.658 0.1818 1.03 0.896 1.19 -0.0267 0.0741 0.719 0.1432 0.974 0.842 1.13 0.0616 0.0756 0.415 0.3819 1.06 0.917 1.23 PRS_PLINK_0.0199526231496888 FALSE 261.41 Rickets or osteomalacia Both 12 139 3 endocrine/metabolic brown 139, 12 35, 3 35, 2 34, 4 35, 3 0.0917 0.292 0.754 0.1229 1.1 0.618 1.94 0.288 0.794 0.717 0.1447 1.33 0.281 6.33 -0.0171 0.818 0.983 0.007297 0.983 0.198 4.88 0.664 0.873 0.447 0.3499 1.94 0.351 10.8 PRS_PLINK_0.0199526231496888 TRUE 262 Mineral deficiency NEC Both 357 3536 3 endocrine/metabolic brown 3536, 357 884, 89 884, 89 884, 78 884, 100 0.0446 0.058 0.442 0.3549 1.05 0.933 1.17 -0.0149 0.157 0.925 0.03408 0.985 0.724 1.34 -0.124 0.164 0.451 0.3454 0.884 0.64 1.22 0.11 0.16 0.492 0.3078 1.12 0.816 1.53 PRS_PLINK_0.0199526231496888 FALSE 263 Other nutritional deficiency Both 456 4263 3 endocrine/metabolic brown 4263, 456 1066, 112 1066, 121 1065, 107 1066, 116 0.0374 0.0506 0.459 0.3378 1.04 0.94 1.15 0.0709 0.138 0.608 0.2162 1.07 0.819 1.41 -0.0142 0.143 0.921 0.03569 0.986 0.744 1.31 0.0836 0.145 0.564 0.2486 1.09 0.818 1.44 PRS_PLINK_0.0199526231496888 FALSE 264 Lack of normal physiological development Both 109 768 3 endocrine/metabolic brown 768, 109 192, 27 192, 27 192, 22 192, 33 0.144 0.108 0.182 0.7391 1.16 0.934 1.43 0.0809 0.292 0.782 0.1069 1.08 0.612 1.92 -0.0988 0.309 0.749 0.1253 0.906 0.494 1.66 0.142 0.294 0.63 0.2006 1.15 0.648 2.05 PRS_PLINK_0.0199526231496888 FALSE 264.2 Failure to thrive (childhood) Both 48 334 3 endocrine/metabolic brown 334, 48 84, 11 83, 13 83, 11 84, 13 0.0948 0.161 0.556 0.2549 1.1 0.802 1.51 0.191 0.428 0.655 0.1839 1.21 0.524 2.8 0.148 0.451 0.742 0.1296 1.16 0.479 2.81 0.0717 0.427 0.867 0.06206 1.07 0.465 2.48 PRS_PLINK_0.0199526231496888 TRUE 264.9 Lack of normal physiological development, unspecified Both 48 327 3 endocrine/metabolic brown 327, 48 82, 16 82, 11 81, 9 82, 12 -0.15 0.162 0.355 0.4498 0.861 0.626 1.18 -0.301 0.42 0.473 0.3255 0.74 0.325 1.68 -0.506 0.457 0.268 0.5713 0.603 0.246 1.48 -0.389 0.44 0.377 0.4239 0.678 0.286 1.61 PRS_PLINK_0.0199526231496888 TRUE 269 Proteinuria Both 287 3347 3 endocrine/metabolic brown 3347, 287 837, 66 837, 75 836, 63 837, 83 0.138 0.064 0.0314 1.502 1.15 1.01 1.3 0.125 0.176 0.476 0.322 1.13 0.803 1.6 -0.064 0.185 0.729 0.1372 0.938 0.653 1.35 0.247 0.181 0.172 0.764 1.28 0.898 1.83 PRS_PLINK_0.0199526231496888 FALSE 270 Disorders of protein plasma/amino-acid transport and metabolism Both 289 2336 3 endocrine/metabolic brown 2336, 289 584, 66 584, 72 584, 52 584, 99 0.148 0.0635 0.0196 1.709 1.16 1.02 1.31 0.099 0.179 0.581 0.2361 1.1 0.777 1.57 -0.224 0.195 0.25 0.6013 0.799 0.545 1.17 0.377 0.176 0.032 1.495 1.46 1.03 2.06 PRS_PLINK_0.0199526231496888 FALSE 270.1 Disturbances of amino-acid transport Both 53 577 3 endocrine/metabolic brown 577, 53 145, 10 144, 16 144, 9 144, 18 0.306 0.145 0.0348 1.459 1.36 1.02 1.8 0.397 0.406 0.327 0.4849 1.49 0.672 3.3 -0.00845 0.455 0.985 0.006477 0.992 0.406 2.42 0.703 0.419 0.0931 1.031 2.02 0.889 4.59 PRS_PLINK_0.0199526231496888 FALSE 270.11 Disturbances of sulphur-bearing amino-acid metabolism Both 50 466 3 endocrine/metabolic brown 466, 50 117, 10 116, 13 116, 7 117, 20 0.363 0.153 0.0181 1.743 1.44 1.06 1.94 0.24 0.43 0.577 0.2389 1.27 0.548 2.95 -0.235 0.492 0.634 0.1981 0.791 0.301 2.08 0.775 0.431 0.072 1.142 2.17 0.933 5.05 PRS_PLINK_0.0199526231496888 TRUE 270.2 Disorders of amino-acid metabolism Both 24 247 3 endocrine/metabolic brown 247, 24 62, 5 62, 7 61, 3 62, 9 0.279 0.213 0.19 0.7222 1.32 0.871 2.01 0.174 0.596 0.77 0.1135 1.19 0.37 3.82 0.086 0.69 0.901 0.0454 1.09 0.282 4.21 0.588 0.582 0.313 0.5051 1.8 0.575 5.64 PRS_PLINK_0.0199526231496888 TRUE 270.3 Disorders of plasma protein metabolism Both 219 1591 3 endocrine/metabolic brown 1591, 219 398, 53 398, 51 397, 43 398, 72 0.112 0.0734 0.126 0.9002 1.12 0.969 1.29 -0.016 0.207 0.938 0.02761 0.984 0.657 1.48 -0.211 0.217 0.331 0.4804 0.81 0.529 1.24 0.272 0.2 0.174 0.7597 1.31 0.887 1.94 PRS_PLINK_0.0199526231496888 FALSE 270.32 Paraproteinemia Both 80 712 3 endocrine/metabolic brown 712, 80 178, 17 178, 14 178, 17 178, 32 0.162 0.117 0.165 0.7818 1.18 0.935 1.48 -0.19 0.359 0.597 0.2239 0.827 0.409 1.67 -0.0772 0.352 0.826 0.08288 0.926 0.465 1.84 0.37 0.333 0.267 0.5738 1.45 0.754 2.78 PRS_PLINK_0.0199526231496888 FALSE 270.33 Amyloidosis Both 23 164 3 endocrine/metabolic brown 164, 23 41, 4 41, 5 41, 6 41, 8 0.166 0.234 0.478 0.3204 1.18 0.747 1.87 0.725 0.779 0.352 0.4533 2.06 0.448 9.51 0.289 0.681 0.671 0.1733 1.34 0.352 5.07 0.41 0.646 0.526 0.2789 1.51 0.425 5.34 PRS_PLINK_0.0199526231496888 TRUE 270.34 Alpha-1-antitrypsin deficiency Both 25 185 3 endocrine/metabolic brown 185, 25 47, 5 46, 7 46, 8 46, 5 -0.0113 0.207 0.957 0.01928 0.989 0.659 1.48 0.374 0.62 0.546 0.2629 1.45 0.432 4.9 0.403 0.618 0.515 0.2882 1.5 0.445 5.03 -0.0122 0.644 0.985 0.006612 0.988 0.279 3.49 PRS_PLINK_0.0199526231496888 TRUE 270.38 Other specified disorders of plasma protein metabolism Both 122 741 3 endocrine/metabolic brown 741, 122 186, 27 185, 31 185, 32 185, 32 0.117 0.104 0.258 0.588 1.12 0.917 1.38 0.126 0.282 0.656 0.1833 1.13 0.653 1.97 0.164 0.282 0.562 0.2503 1.18 0.677 2.05 0.251 0.288 0.383 0.4168 1.29 0.731 2.26 PRS_PLINK_0.0199526231496888 FALSE 271 Disorders of carbohydrate transport and metabolism Both 580 7084 3 endocrine/metabolic brown 7084, 580 1770, 153 1771, 145 1771, 132 1771, 150 0.0347 0.0446 0.437 0.3595 1.04 0.949 1.13 -0.0129 0.121 0.915 0.03845 0.987 0.779 1.25 -0.105 0.125 0.4 0.3985 0.9 0.704 1.15 0.0234 0.125 0.851 0.07001 1.02 0.802 1.31 PRS_PLINK_0.0199526231496888 FALSE 271.3 Intestinal disaccharidase deficiencies and disaccharide malabsorption Both 557 6858 3 endocrine/metabolic brown 6858, 557 1714, 148 1714, 136 1714, 129 1715, 144 0.0277 0.0456 0.543 0.2648 1.03 0.94 1.12 -0.0436 0.124 0.725 0.1399 0.957 0.751 1.22 -0.0943 0.127 0.458 0.3395 0.91 0.71 1.17 0.0053 0.127 0.967 0.01469 1.01 0.784 1.29 PRS_PLINK_0.0199526231496888 FALSE 271.9 Other disorders of carbohydrate transport and metabolism Both 27 299 3 endocrine/metabolic brown 299, 27 75, 7 75, 10 74, 5 75, 5 0.0144 0.188 0.939 0.02734 1.01 0.702 1.47 0.428 0.495 0.387 0.4121 1.53 0.582 4.05 -0.216 0.556 0.697 0.1568 0.805 0.271 2.39 0.085 0.584 0.884 0.05338 1.09 0.347 3.42 PRS_PLINK_0.0199526231496888 TRUE 272 Disorders of lipoid metabolism Both 3646 8678 3 endocrine/metabolic brown 8678, 3646 2170, 927 2169, 849 2169, 936 2170, 933 0.0945 0.0228 3.4e-05 4.468 1.1 1.05 1.15 -0.0285 0.063 0.651 0.1864 0.972 0.859 1.1 0.11 0.0634 0.0818 1.087 1.12 0.986 1.26 0.207 0.0656 0.00163 2.788 1.23 1.08 1.4 PRS_PLINK_0.0199526231496888 FALSE 272.1 Hyperlipidemia Both 3635 8673 3 endocrine/metabolic brown 8673, 3635 2169, 922 2168, 846 2168, 936 2168, 930 0.0943 0.0228 3.59e-05 4.445 1.1 1.05 1.15 -0.0271 0.0631 0.668 0.1751 0.973 0.86 1.1 0.115 0.0634 0.0703 1.153 1.12 0.991 1.27 0.208 0.0658 0.00157 2.804 1.23 1.08 1.4 PRS_PLINK_0.0199526231496888 FALSE 272.11 Hypercholesterolemia Both 1031 6216 3 endocrine/metabolic brown 6216, 1031 1554, 248 1554, 232 1554, 273 1554, 278 0.137 0.0373 0.000246 3.609 1.15 1.07 1.23 -0.0142 0.104 0.891 0.04989 0.986 0.804 1.21 0.195 0.103 0.0585 1.233 1.22 0.993 1.49 0.304 0.106 0.00429 2.368 1.36 1.1 1.67 PRS_PLINK_0.0199526231496888 FALSE 272.12 Hyperglyceridemia Both 242 3080 3 endocrine/metabolic brown 3080, 242 770, 58 770, 53 770, 67 770, 64 0.0903 0.0697 0.195 0.7094 1.09 0.955 1.25 -0.0841 0.197 0.669 0.1744 0.919 0.625 1.35 0.174 0.189 0.356 0.4489 1.19 0.823 1.72 0.147 0.196 0.452 0.3447 1.16 0.789 1.7 PRS_PLINK_0.0199526231496888 FALSE 272.13 Mixed hyperlipidemia Both 604 4857 3 endocrine/metabolic brown 4857, 604 1215, 156 1214, 138 1214, 147 1214, 163 0.0984 0.0475 0.0382 1.418 1.1 1.01 1.21 -0.0512 0.132 0.697 0.1565 0.95 0.734 1.23 -0.0113 0.132 0.932 0.0306 0.989 0.763 1.28 0.168 0.135 0.211 0.6761 1.18 0.909 1.54 PRS_PLINK_0.0199526231496888 FALSE 272.9 Unspecified disorder of lipoid metabolism Both 55 692 3 endocrine/metabolic brown 692, 55 173, 13 173, 14 173, 15 173, 13 0.00124 0.144 0.993 0.003 1 0.755 1.33 0.192 0.395 0.626 0.2035 1.21 0.559 2.63 0.205 0.382 0.591 0.2281 1.23 0.581 2.59 -0.0825 0.413 0.842 0.07491 0.921 0.41 2.07 PRS_PLINK_0.0199526231496888 FALSE 274 Gout and other crystal arthropathies Both 489 4546 3 endocrine/metabolic brown 4546, 489 1137, 116 1136, 108 1136, 122 1137, 143 0.114 0.0482 0.0178 1.749 1.12 1.02 1.23 -0.0609 0.14 0.664 0.1781 0.941 0.715 1.24 0.0508 0.137 0.711 0.1478 1.05 0.804 1.38 0.286 0.138 0.039 1.409 1.33 1.01 1.74 PRS_PLINK_0.0199526231496888 FALSE 274.1 Gout Both 458 4366 3 endocrine/metabolic brown 4366, 458 1092, 104 1091, 99 1091, 118 1092, 137 0.139 0.0498 0.00531 2.275 1.15 1.04 1.27 -0.0342 0.146 0.815 0.08882 0.966 0.726 1.29 0.12 0.142 0.396 0.4021 1.13 0.854 1.49 0.352 0.143 0.0139 1.855 1.42 1.07 1.88 PRS_PLINK_0.0199526231496888 FALSE 274.11 Gouty arthropathy Both 237 2104 3 endocrine/metabolic brown 2104, 237 526, 56 526, 41 526, 63 526, 77 0.182 0.0684 0.0077 2.114 1.2 1.05 1.37 -0.316 0.213 0.139 0.8569 0.729 0.48 1.11 0.125 0.194 0.519 0.2846 1.13 0.775 1.66 0.367 0.196 0.0606 1.218 1.44 0.984 2.12 PRS_PLINK_0.0199526231496888 FALSE 274.2 Crystal arthropathies Both 48 322 3 endocrine/metabolic brown 322, 48 81, 16 80, 12 80, 6 81, 14 -0.0965 0.146 0.508 0.2937 0.908 0.682 1.21 -0.192 0.413 0.643 0.1921 0.826 0.368 1.85 -0.754 0.471 0.11 0.959 0.471 0.187 1.19 -0.169 0.422 0.689 0.1618 0.845 0.369 1.93 PRS_PLINK_0.0199526231496888 TRUE 274.21 Chondrocalcinosis Both 42 298 3 endocrine/metabolic brown 298, 42 75, 16 74, 9 74, 8 75, 9 -0.184 0.155 0.236 0.6279 0.832 0.614 1.13 -0.489 0.442 0.269 0.5697 0.613 0.258 1.46 -0.44 0.454 0.332 0.4783 0.644 0.265 1.57 -0.512 0.468 0.274 0.5627 0.599 0.24 1.5 PRS_PLINK_0.0199526231496888 TRUE 275 Disorders of mineral metabolism Both 1032 9586 3 endocrine/metabolic brown 9586, 1032 2396, 245 2396, 243 2396, 255 2397, 289 0.105 0.0336 0.00184 2.736 1.11 1.04 1.19 0.00498 0.0954 0.958 0.01846 1 0.834 1.21 0.0554 0.0957 0.563 0.2497 1.06 0.876 1.28 0.181 0.0959 0.0598 1.223 1.2 0.993 1.45 PRS_PLINK_0.0199526231496888 FALSE 275.1 Disorders of iron metabolism Both 66 556 4 hematopoietic darkorange1 556, 66 139, 21 139, 14 139, 14 139, 17 -0.0573 0.128 0.654 0.1843 0.944 0.735 1.21 -0.394 0.354 0.265 0.5761 0.674 0.337 1.35 -0.4 0.353 0.257 0.5899 0.67 0.335 1.34 -0.29 0.345 0.4 0.3975 0.748 0.381 1.47 PRS_PLINK_0.0199526231496888 FALSE 275.11 Hereditary hemochromatosis Both 25 259 4 hematopoietic darkorange1 259, 25 65, 10 65, 5 64, 4 65, 6 -0.206 0.195 0.291 0.5366 0.814 0.555 1.19 -0.787 0.554 0.156 0.8081 0.455 0.153 1.35 -1.04 0.59 0.0792 1.101 0.355 0.112 1.13 -0.528 0.542 0.33 0.4811 0.59 0.204 1.71 PRS_PLINK_0.0199526231496888 TRUE 275.2 Disorders of copper metabolism Both 23 185 3 endocrine/metabolic brown 185, 23 47, 10 46, 5 46, 2 46, 6 -0.177 0.222 0.425 0.3717 0.838 0.543 1.29 -0.377 0.607 0.535 0.2715 0.686 0.209 2.26 -0.965 0.726 0.183 0.7368 0.381 0.0919 1.58 -0.512 0.591 0.386 0.4129 0.599 0.188 1.91 PRS_PLINK_0.0199526231496888 TRUE 275.3 Disorders of magnesium metabolism Both 315 2817 3 endocrine/metabolic brown 2817, 315 704, 59 704, 77 704, 87 704, 92 0.177 0.0614 0.00388 2.412 1.19 1.06 1.35 0.261 0.18 0.147 0.8322 1.3 0.912 1.85 0.415 0.18 0.0211 1.675 1.51 1.06 2.15 0.455 0.183 0.013 1.887 1.58 1.1 2.26 PRS_PLINK_0.0199526231496888 FALSE 275.5 Disorders of calcium/phosphorus metabolism Both 777 7978 3 endocrine/metabolic brown 7978, 777 1994, 181 1994, 182 1994, 192 1995, 222 0.108 0.0387 0.00511 2.291 1.11 1.03 1.2 0.0123 0.11 0.911 0.04051 1.01 0.816 1.26 0.0707 0.11 0.521 0.2835 1.07 0.865 1.33 0.209 0.11 0.0575 1.24 1.23 0.993 1.53 PRS_PLINK_0.0199526231496888 FALSE 275.51 Hypocalcemia Both 210 2384 3 endocrine/metabolic brown 2384, 210 595, 52 596, 49 596, 54 596, 55 0.09 0.0744 0.227 0.6448 1.09 0.946 1.27 -0.0758 0.205 0.712 0.1478 0.927 0.62 1.39 0.0236 0.206 0.909 0.04162 1.02 0.684 1.53 0.133 0.211 0.529 0.2766 1.14 0.755 1.73 PRS_PLINK_0.0199526231496888 FALSE 275.53 Disorders of phosphorus metabolism Both 381 3255 3 endocrine/metabolic brown 3255, 381 814, 73 814, 103 813, 92 814, 113 0.186 0.0545 0.000667 3.176 1.2 1.08 1.34 0.391 0.162 0.0156 1.806 1.48 1.08 2.03 0.284 0.168 0.0916 1.038 1.33 0.955 1.85 0.475 0.168 0.00467 2.33 1.61 1.16 2.23 PRS_PLINK_0.0199526231496888 FALSE 275.6 Hypercalcemia Both 264 3280 3 endocrine/metabolic brown 3280, 264 820, 65 820, 67 820, 62 820, 70 0.0893 0.0659 0.175 0.7566 1.09 0.961 1.24 0.00741 0.179 0.967 0.01455 1.01 0.709 1.43 -0.0112 0.185 0.952 0.02154 0.989 0.688 1.42 0.0616 0.186 0.74 0.1308 1.06 0.739 1.53 PRS_PLINK_0.0199526231496888 FALSE 276 Disorders of fluid, electrolyte, and acid-base balance Both 2588 10057 3 endocrine/metabolic brown 10057, 2588 2515, 615 2514, 634 2514, 652 2514, 686 0.1 0.0232 1.68e-05 4.774 1.11 1.06 1.16 0.06 0.0649 0.355 0.4495 1.06 0.935 1.21 0.084 0.0657 0.201 0.6976 1.09 0.956 1.24 0.189 0.067 0.00482 2.317 1.21 1.06 1.38 PRS_PLINK_0.0199526231496888 FALSE 276.1 Electrolyte imbalance Both 1601 8864 3 endocrine/metabolic brown 8864, 1601 2216, 372 2216, 380 2216, 417 2216, 431 0.133 0.0285 2.83e-06 5.549 1.14 1.08 1.21 0.0621 0.0807 0.441 0.3553 1.06 0.908 1.25 0.148 0.0807 0.0659 1.181 1.16 0.99 1.36 0.237 0.0826 0.00416 2.381 1.27 1.08 1.49 PRS_PLINK_0.0199526231496888 FALSE 276.11 Hyperosmolality and/or hypernatremia Both 170 1046 3 endocrine/metabolic brown 1046, 170 262, 33 261, 43 261, 42 262, 52 0.209 0.0848 0.0136 1.868 1.23 1.04 1.46 0.262 0.248 0.29 0.5377 1.3 0.8 2.11 0.234 0.253 0.355 0.4499 1.26 0.77 2.08 0.385 0.252 0.126 0.9005 1.47 0.898 2.41 PRS_PLINK_0.0199526231496888 FALSE 276.12 Hyposmolality and/or hyponatremia Both 702 4715 3 endocrine/metabolic brown 4715, 702 1179, 162 1179, 169 1178, 180 1179, 191 0.153 0.0415 0.000223 3.653 1.17 1.07 1.26 0.0698 0.118 0.554 0.2563 1.07 0.851 1.35 0.127 0.118 0.281 0.5514 1.14 0.901 1.43 0.186 0.12 0.122 0.9125 1.2 0.951 1.52 PRS_PLINK_0.0199526231496888 FALSE 276.13 Hyperpotassemia Both 709 5346 3 endocrine/metabolic brown 5346, 709 1337, 151 1336, 162 1336, 178 1337, 217 0.201 0.0415 1.27e-06 5.897 1.22 1.13 1.33 0.108 0.12 0.37 0.4314 1.11 0.88 1.41 0.178 0.12 0.138 0.8608 1.19 0.945 1.51 0.447 0.119 0.000171 3.768 1.56 1.24 1.97 PRS_PLINK_0.0199526231496888 FALSE 276.14 Hypopotassemia Both 633 4977 3 endocrine/metabolic brown 4977, 633 1245, 133 1244, 145 1244, 169 1244, 186 0.174 0.0438 7.07e-05 4.151 1.19 1.09 1.3 0.0998 0.126 0.43 0.3668 1.1 0.862 1.42 0.241 0.124 0.0529 1.276 1.27 0.997 1.62 0.36 0.126 0.00428 2.368 1.43 1.12 1.84 PRS_PLINK_0.0199526231496888 FALSE 276.4 Acid-base balance disorder Both 667 4458 3 endocrine/metabolic brown 4458, 667 1115, 143 1114, 158 1114, 171 1115, 194 0.163 0.043 0.000155 3.81 1.18 1.08 1.28 0.112 0.124 0.367 0.4355 1.12 0.877 1.43 0.194 0.123 0.117 0.9331 1.21 0.953 1.55 0.296 0.124 0.0173 1.763 1.34 1.05 1.72 PRS_PLINK_0.0199526231496888 FALSE 276.41 Acidosis Both 557 3851 3 endocrine/metabolic brown 3851, 557 963, 118 963, 134 962, 144 963, 160 0.165 0.0465 0.000396 3.402 1.18 1.08 1.29 0.142 0.135 0.292 0.5343 1.15 0.885 1.5 0.219 0.135 0.105 0.9798 1.25 0.955 1.62 0.303 0.137 0.0264 1.579 1.35 1.04 1.77 PRS_PLINK_0.0199526231496888 FALSE 276.42 Alkalosis Both 190 958 3 endocrine/metabolic brown 958, 190 240, 40 239, 50 239, 46 240, 53 0.124 0.0839 0.139 0.8567 1.13 0.96 1.33 0.256 0.231 0.268 0.5726 1.29 0.821 2.03 0.197 0.237 0.406 0.3917 1.22 0.765 1.94 0.271 0.24 0.26 0.5846 1.31 0.818 2.1 PRS_PLINK_0.0199526231496888 FALSE 276.5 Hypovolemia Both 1419 9169 3 endocrine/metabolic brown 9169, 1419 2293, 338 2292, 340 2292, 364 2292, 376 0.0928 0.0296 0.0017 2.769 1.1 1.04 1.16 0.0115 0.083 0.89 0.05064 1.01 0.86 1.19 0.0808 0.083 0.331 0.4806 1.08 0.921 1.28 0.148 0.0848 0.0799 1.097 1.16 0.982 1.37 PRS_PLINK_0.0199526231496888 FALSE 276.6 Fluid overload Both 457 2575 3 endocrine/metabolic brown 2575, 457 644, 79 644, 103 643, 118 644, 157 0.296 0.0526 1.95e-08 7.71 1.34 1.21 1.49 0.323 0.161 0.0457 1.34 1.38 1.01 1.9 0.434 0.158 0.00608 2.216 1.54 1.13 2.1 0.766 0.157 1.14e-06 5.944 2.15 1.58 2.93 PRS_PLINK_0.0199526231496888 FALSE 276.8 Polydipsia Both 36 389 3 endocrine/metabolic brown 389, 36 98, 7 97, 10 97, 9 97, 10 0.0727 0.175 0.678 0.1686 1.08 0.763 1.52 0.165 0.483 0.733 0.1348 1.18 0.458 3.04 0.132 0.5 0.792 0.1013 1.14 0.428 3.04 0.195 0.508 0.701 0.1541 1.22 0.449 3.29 PRS_PLINK_0.0199526231496888 TRUE 277 Other disorders of metabolism Both 1048 9852 3 endocrine/metabolic brown 9852, 1048 2462, 246 2463, 283 2463, 251 2463, 268 0.0309 0.0337 0.358 0.4456 1.03 0.966 1.1 0.142 0.0924 0.125 0.9016 1.15 0.961 1.38 0.0246 0.0963 0.798 0.09794 1.02 0.849 1.24 0.0985 0.0979 0.314 0.5026 1.1 0.911 1.34 PRS_PLINK_0.0199526231496888 FALSE 277.2 Other disorders of purine and pyrimidine metabolism Both 67 802 3 endocrine/metabolic brown 802, 67 201, 16 200, 14 200, 18 201, 19 0.188 0.127 0.139 0.8571 1.21 0.941 1.55 0.0519 0.369 0.888 0.05156 1.05 0.511 2.17 0.291 0.359 0.418 0.3793 1.34 0.662 2.71 0.388 0.365 0.288 0.5406 1.47 0.721 3.01 PRS_PLINK_0.0199526231496888 FALSE 277.4 Disorders of bilirubin excretion Both 235 1678 3 endocrine/metabolic brown 1678, 235 420, 61 419, 62 419, 55 420, 57 -0.0231 0.0702 0.742 0.1295 0.977 0.852 1.12 -0.0102 0.193 0.958 0.01872 0.99 0.678 1.45 -0.137 0.204 0.502 0.299 0.872 0.584 1.3 -0.0265 0.207 0.898 0.04669 0.974 0.649 1.46 PRS_PLINK_0.0199526231496888 FALSE 277.5 Other disorders of lipoid metabolism Both 247 2484 3 endocrine/metabolic brown 2484, 247 621, 63 621, 58 621, 72 621, 54 -0.0551 0.07 0.431 0.3654 0.946 0.825 1.09 -0.153 0.191 0.423 0.3732 0.858 0.591 1.25 0.107 0.184 0.561 0.251 1.11 0.776 1.59 -0.149 0.198 0.452 0.3447 0.861 0.584 1.27 PRS_PLINK_0.0199526231496888 FALSE 277.51 Lipoprotein disorders Both 207 2019 3 endocrine/metabolic brown 2019, 207 505, 50 505, 53 504, 57 505, 47 -0.0652 0.0757 0.389 0.41 0.937 0.808 1.09 0.0224 0.207 0.914 0.0392 1.02 0.682 1.53 0.103 0.205 0.617 0.2094 1.11 0.741 1.66 -0.0345 0.218 0.874 0.05827 0.966 0.63 1.48 PRS_PLINK_0.0199526231496888 FALSE 277.7 Dysmetabolic syndrome X Both 157 2400 3 endocrine/metabolic brown 2400, 157 600, 37 600, 49 600, 35 600, 36 -0.0656 0.0851 0.441 0.3557 0.936 0.793 1.11 0.274 0.221 0.216 0.665 1.31 0.852 2.03 -0.11 0.241 0.648 0.1884 0.896 0.559 1.44 -0.165 0.248 0.506 0.2959 0.848 0.522 1.38 PRS_PLINK_0.0199526231496888 FALSE 278 Overweight, obesity and other hyperalimentation Both 4202 8627 3 endocrine/metabolic brown 8627, 4202 2157, 1014 2157, 979 2156, 1069 2157, 1139 0.0811 0.0196 3.58e-05 4.446 1.08 1.04 1.13 -0.0274 0.0552 0.62 0.2079 0.973 0.873 1.08 0.0646 0.0549 0.239 0.6214 1.07 0.958 1.19 0.14 0.0562 0.0126 1.898 1.15 1.03 1.28 PRS_PLINK_0.0199526231496888 FALSE 278.1 Obesity Both 3397 8620 3 endocrine/metabolic brown 8620, 3397 2155, 802 2155, 795 2155, 865 2155, 935 0.0957 0.0212 6.28e-06 5.202 1.1 1.06 1.15 -0.0069 0.0598 0.908 0.04185 0.993 0.883 1.12 0.0831 0.0595 0.162 0.7897 1.09 0.967 1.22 0.174 0.0606 0.00411 2.386 1.19 1.06 1.34 PRS_PLINK_0.0199526231496888 FALSE 278.11 Morbid obesity Both 1517 8570 3 endocrine/metabolic brown 8570, 1517 2143, 331 2142, 354 2142, 397 2143, 435 0.141 0.0291 1.33e-06 5.875 1.15 1.09 1.22 0.0745 0.0835 0.372 0.4297 1.08 0.915 1.27 0.2 0.0824 0.0155 1.81 1.22 1.04 1.44 0.308 0.0838 0.000237 3.625 1.36 1.15 1.6 PRS_PLINK_0.0199526231496888 FALSE 278.3 Localized adiposity Both 110 1131 3 endocrine/metabolic brown 1131, 110 283, 28 283, 24 282, 33 283, 25 0.0231 0.103 0.823 0.08445 1.02 0.836 1.25 -0.221 0.286 0.44 0.357 0.802 0.458 1.4 0.122 0.274 0.657 0.1824 1.13 0.66 1.93 -0.195 0.292 0.505 0.2967 0.823 0.464 1.46 PRS_PLINK_0.0199526231496888 FALSE 278.4 Abnormal weight gain Both 693 6446 3 endocrine/metabolic brown 6446, 693 1612, 162 1611, 165 1611, 169 1612, 197 0.0797 0.0419 0.0572 1.243 1.08 0.998 1.18 0.0171 0.116 0.883 0.05409 1.02 0.81 1.28 0.0349 0.118 0.766 0.1155 1.04 0.822 1.3 0.174 0.118 0.14 0.8532 1.19 0.945 1.5 PRS_PLINK_0.0199526231496888 FALSE 279 Disorders involving the immune mechanism Both 850 7915 3 endocrine/metabolic brown 7915, 850 1979, 204 1979, 232 1978, 196 1979, 217 0.031 0.0371 0.404 0.3935 1.03 0.959 1.11 0.135 0.101 0.183 0.7373 1.14 0.938 1.4 -0.0265 0.107 0.804 0.09497 0.974 0.79 1.2 0.0937 0.107 0.382 0.4182 1.1 0.89 1.35 PRS_PLINK_0.0199526231496888 FALSE 279.1 Immunity deficiency Both 337 3145 3 endocrine/metabolic brown 3145, 337 787, 91 786, 90 786, 74 786, 81 -0.0373 0.0593 0.53 0.2761 0.963 0.858 1.08 -0.00822 0.157 0.958 0.01849 0.992 0.729 1.35 -0.241 0.166 0.145 0.8372 0.786 0.568 1.09 -0.139 0.167 0.404 0.3933 0.87 0.627 1.21 PRS_PLINK_0.0199526231496888 FALSE 279.11 Deficiency of humoral immunity Both 89 854 3 endocrine/metabolic brown 854, 89 214, 23 213, 21 213, 18 214, 27 0.163 0.114 0.153 0.8157 1.18 0.941 1.47 -0.126 0.311 0.685 0.1643 0.881 0.479 1.62 -0.289 0.326 0.375 0.4258 0.749 0.396 1.42 0.139 0.3 0.643 0.1921 1.15 0.638 2.07 PRS_PLINK_0.0199526231496888 FALSE 279.2 Autoimmune disease NEC Both 240 2180 3 endocrine/metabolic brown 2180, 240 545, 55 545, 59 545, 60 545, 65 6.92e-05 0.071 0.999 0.0003379 1 0.87 1.15 0.0677 0.196 0.729 0.1371 1.07 0.729 1.57 0.0648 0.197 0.742 0.1293 1.07 0.725 1.57 0.188 0.2 0.347 0.4594 1.21 0.815 1.79 PRS_PLINK_0.0199526231496888 FALSE 279.7 Other immunological findings Both 1329 9941 3 endocrine/metabolic brown 9941, 1329 2486, 314 2485, 331 2485, 349 2485, 334 0.0375 0.0302 0.215 0.6681 1.04 0.978 1.1 0.06 0.0842 0.476 0.3222 1.06 0.9 1.25 0.121 0.0847 0.153 0.8152 1.13 0.956 1.33 0.0948 0.0879 0.281 0.5518 1.1 0.925 1.31 PRS_PLINK_0.0199526231496888 FALSE 279.8 Other specified disorders involving the immune mechanism Both 206 1841 3 endocrine/metabolic brown 1841, 206 461, 48 460, 52 460, 46 460, 59 0.0237 0.0774 0.759 0.1196 1.02 0.88 1.19 0.0887 0.208 0.67 0.1737 1.09 0.726 1.64 -0.0432 0.218 0.842 0.07445 0.958 0.625 1.47 0.19 0.211 0.367 0.4353 1.21 0.8 1.83 PRS_PLINK_0.0199526231496888 FALSE 280 Iron deficiency anemias Both 1442 8110 4 hematopoietic darkorange1 8110, 1442 2028, 317 2027, 362 2027, 350 2028, 412 0.132 0.0297 8.38e-06 5.077 1.14 1.08 1.21 0.154 0.0838 0.0671 1.173 1.17 0.989 1.37 0.147 0.0856 0.0857 1.067 1.16 0.98 1.37 0.298 0.0855 0.000484 3.315 1.35 1.14 1.59 PRS_PLINK_0.0199526231496888 FALSE 280.1 Iron deficiency anemias, unspecified or not due to blood loss Both 1390 8068 4 hematopoietic darkorange1 8068, 1390 2017, 306 2017, 349 2017, 336 2017, 398 0.131 0.0302 1.45e-05 4.839 1.14 1.07 1.21 0.148 0.0851 0.0825 1.083 1.16 0.981 1.37 0.136 0.087 0.119 0.9239 1.15 0.966 1.36 0.291 0.0867 0.000805 3.094 1.34 1.13 1.58 PRS_PLINK_0.0199526231496888 FALSE 280.2 Iron deficiency anemia secondary to blood loss (chronic) Both 589 4183 4 hematopoietic darkorange1 4183, 589 1046, 111 1046, 154 1045, 151 1046, 172 0.174 0.046 0.000153 3.814 1.19 1.09 1.3 0.333 0.132 0.0118 1.929 1.4 1.08 1.81 0.344 0.135 0.011 1.96 1.41 1.08 1.84 0.414 0.137 0.00244 2.613 1.51 1.16 1.98 PRS_PLINK_0.0199526231496888 FALSE 281 Other deficiency anemia Both 159 1126 4 hematopoietic darkorange1 1126, 159 282, 25 281, 44 281, 47 282, 43 0.169 0.0875 0.0537 1.27 1.18 0.997 1.41 0.559 0.263 0.0334 1.476 1.75 1.04 2.93 0.658 0.263 0.0123 1.912 1.93 1.15 3.23 0.499 0.275 0.0692 1.16 1.65 0.961 2.82 PRS_PLINK_0.0199526231496888 FALSE 281.1 Megaloblastic anemia Both 74 573 4 hematopoietic darkorange1 573, 74 144, 17 143, 18 143, 24 143, 15 0.0552 0.126 0.661 0.1801 1.06 0.826 1.35 -0.0338 0.359 0.925 0.03381 0.967 0.478 1.95 0.384 0.343 0.263 0.5803 1.47 0.749 2.88 -0.221 0.38 0.562 0.2502 0.802 0.381 1.69 PRS_PLINK_0.0199526231496888 FALSE 281.11 Pernicious anemia Both 25 239 4 hematopoietic darkorange1 239, 25 60, 3 60, 7 59, 7 60, 8 0.171 0.215 0.427 0.3696 1.19 0.778 1.81 0.643 0.682 0.346 0.461 1.9 0.5 7.24 0.516 0.694 0.457 0.34 1.68 0.43 6.53 0.334 0.653 0.609 0.2152 1.4 0.388 5.02 PRS_PLINK_0.0199526231496888 TRUE 281.12 Other vitamin B12 deficiency anemia Both 54 420 4 hematopoietic darkorange1 420, 54 105, 17 105, 14 105, 14 105, 9 -0.127 0.141 0.366 0.4363 0.88 0.668 1.16 -0.0763 0.389 0.845 0.0734 0.927 0.432 1.99 -0.0897 0.387 0.817 0.08798 0.914 0.428 1.95 -0.632 0.433 0.145 0.8398 0.531 0.227 1.24 PRS_PLINK_0.0199526231496888 FALSE 281.9 Deficiency anemias Both 93 584 4 hematopoietic darkorange1 584, 93 146, 11 146, 21 146, 30 146, 31 0.315 0.116 0.00654 2.184 1.37 1.09 1.72 0.576 0.384 0.134 0.8745 1.78 0.838 3.77 1.07 0.373 0.00393 2.406 2.93 1.41 6.08 0.929 0.373 0.0128 1.892 2.53 1.22 5.27 PRS_PLINK_0.0199526231496888 FALSE 282 Hereditary hemolytic anemias Both 100 747 4 hematopoietic darkorange1 747, 100 187, 29 187, 21 186, 23 187, 27 -0.0159 0.109 0.885 0.05328 0.984 0.795 1.22 -0.266 0.299 0.374 0.4276 0.766 0.426 1.38 -0.215 0.296 0.468 0.3301 0.806 0.451 1.44 -0.172 0.301 0.567 0.2462 0.842 0.467 1.52 PRS_PLINK_0.0199526231496888 FALSE 282.8 Other hemoglobinopathies Both 65 482 4 hematopoietic darkorange1 482, 65 121, 17 120, 10 120, 16 121, 22 0.17 0.136 0.211 0.6766 1.19 0.908 1.55 -0.355 0.404 0.379 0.4209 0.701 0.318 1.55 0.0622 0.371 0.867 0.06204 1.06 0.514 2.2 0.178 0.364 0.626 0.2037 1.19 0.585 2.44 PRS_PLINK_0.0199526231496888 FALSE 282.9 Other hereditary hemolytic anemias Both 51 407 4 hematopoietic darkorange1 407, 51 102, 14 102, 15 101, 10 102, 12 -0.0416 0.156 0.79 0.1024 0.959 0.706 1.3 0.0186 0.386 0.962 0.01704 1.02 0.478 2.17 -0.258 0.422 0.542 0.2663 0.773 0.338 1.77 -0.0588 0.434 0.892 0.04954 0.943 0.403 2.21 PRS_PLINK_0.0199526231496888 FALSE 283 Acquired hemolytic anemias Both 57 351 4 hematopoietic darkorange1 351, 57 88, 6 88, 16 87, 15 88, 20 0.38 0.157 0.0157 1.805 1.46 1.07 1.99 1.02 0.487 0.0364 1.439 2.77 1.07 7.2 0.904 0.489 0.0643 1.192 2.47 0.948 6.44 1.1 0.486 0.0241 1.618 2.99 1.15 7.74 PRS_PLINK_0.0199526231496888 FALSE 283.1 Autoimmune hemolytic anemias Both 17 136 4 hematopoietic darkorange1 136, 17 34, 2 34, 5 34, 6 34, 4 0.284 0.265 0.284 0.5462 1.33 0.79 2.23 0.988 0.98 0.313 0.504 2.68 0.394 18.3 0.634 0.826 0.443 0.3536 1.88 0.373 9.51 0.148 0.791 0.852 0.06949 1.16 0.246 5.47 PRS_PLINK_0.0199526231496888 TRUE 284 Aplastic anemia Both 244 1551 4 hematopoietic darkorange1 1551, 244 388, 46 388, 62 387, 76 388, 60 0.125 0.0708 0.077 1.113 1.13 0.987 1.3 0.342 0.209 0.101 0.9965 1.41 0.936 2.12 0.56 0.206 0.00651 2.186 1.75 1.17 2.62 0.283 0.22 0.198 0.7031 1.33 0.863 2.04 PRS_PLINK_0.0199526231496888 FALSE 284.1 Pancytopenia Both 214 1378 4 hematopoietic darkorange1 1378, 214 345, 38 344, 57 344, 69 345, 50 0.127 0.0759 0.0946 1.024 1.14 0.978 1.32 0.447 0.224 0.0465 1.333 1.56 1.01 2.43 0.668 0.223 0.00276 2.559 1.95 1.26 3.02 0.323 0.241 0.179 0.7462 1.38 0.862 2.22 PRS_PLINK_0.0199526231496888 FALSE 285 Other anemias Both 3669 8751 4 hematopoietic darkorange1 8751, 3669 2188, 871 2188, 959 2187, 892 2188, 946 0.0695 0.0206 0.000747 3.127 1.07 1.03 1.12 0.123 0.057 0.0308 1.512 1.13 1.01 1.26 0.0601 0.0585 0.304 0.5169 1.06 0.947 1.19 0.129 0.0596 0.0302 1.519 1.14 1.01 1.28 PRS_PLINK_0.0199526231496888 FALSE 285.1 Acute posthemorrhagic anemia Both 1142 6514 4 hematopoietic darkorange1 6514, 1142 1629, 267 1628, 306 1628, 268 1629, 300 0.0878 0.0332 0.00827 2.082 1.09 1.02 1.17 0.157 0.0918 0.0878 1.056 1.17 0.977 1.4 0.049 0.0956 0.608 0.2158 1.05 0.871 1.27 0.153 0.096 0.111 0.9555 1.17 0.966 1.41 PRS_PLINK_0.0199526231496888 FALSE 285.2 Anemia of chronic disease Both 576 4299 4 hematopoietic darkorange1 4299, 576 1075, 123 1075, 134 1074, 157 1075, 161 0.141 0.0461 0.00216 2.666 1.15 1.05 1.26 0.108 0.133 0.416 0.3814 1.11 0.859 1.44 0.247 0.131 0.0582 1.235 1.28 0.991 1.65 0.318 0.134 0.0172 1.763 1.37 1.06 1.79 PRS_PLINK_0.0199526231496888 FALSE 285.21 Anemia in chronic kidney disease Both 166 1817 4 hematopoietic darkorange1 1817, 166 455, 27 454, 38 454, 44 454, 57 0.33 0.0852 0.000109 3.962 1.39 1.18 1.64 0.387 0.258 0.134 0.8737 1.47 0.888 2.44 0.542 0.253 0.0319 1.496 1.72 1.05 2.82 0.911 0.254 0.000339 3.47 2.49 1.51 4.09 PRS_PLINK_0.0199526231496888 FALSE 285.22 Anemia in neoplastic disease Both 248 1555 4 hematopoietic darkorange1 1555, 248 389, 64 389, 61 388, 61 389, 62 0.00685 0.0718 0.924 0.03432 1.01 0.875 1.16 -0.0481 0.193 0.803 0.09516 0.953 0.653 1.39 -0.117 0.198 0.553 0.2572 0.889 0.603 1.31 -0.0642 0.202 0.751 0.1243 0.938 0.631 1.39 PRS_PLINK_0.0199526231496888 FALSE 286 Coagulation defects Both 1231 8384 4 hematopoietic darkorange1 8384, 1231 2096, 261 2096, 297 2096, 337 2096, 335 0.144 0.0318 5.62e-06 5.25 1.16 1.09 1.23 0.156 0.0912 0.0881 1.055 1.17 0.977 1.4 0.254 0.0901 0.00481 2.318 1.29 1.08 1.54 0.255 0.0933 0.00626 2.203 1.29 1.07 1.55 PRS_PLINK_0.0199526231496888 FALSE 286.1 Congenital coagulation defects Both 74 752 4 hematopoietic darkorange1 752, 74 188, 18 188, 14 188, 26 188, 16 0.0551 0.13 0.671 0.173 1.06 0.819 1.36 -0.247 0.354 0.485 0.3144 0.781 0.39 1.56 0.431 0.321 0.179 0.7474 1.54 0.821 2.88 -0.075 0.356 0.833 0.07912 0.928 0.461 1.87 PRS_PLINK_0.0199526231496888 FALSE 286.11 Von willebrand's disease Both 24 247 4 hematopoietic darkorange1 247, 24 62, 5 62, 3 61, 7 62, 9 0.322 0.223 0.148 0.8294 1.38 0.892 2.13 -0.405 0.678 0.551 0.2591 0.667 0.176 2.52 0.477 0.595 0.423 0.3742 1.61 0.502 5.17 0.16 0.586 0.785 0.1049 1.17 0.372 3.7 PRS_PLINK_0.0199526231496888 TRUE 286.12 Congenital deficiency of other clotting factors (including factor VII) Both 40 395 4 hematopoietic darkorange1 395, 40 99, 10 99, 11 98, 16 99, 3 -0.21 0.168 0.21 0.6773 0.81 0.583 1.13 0.0763 0.445 0.864 0.06361 1.08 0.451 2.58 0.385 0.411 0.35 0.456 1.47 0.656 3.29 -0.989 0.592 0.0948 1.023 0.372 0.117 1.19 PRS_PLINK_0.0199526231496888 TRUE 286.2 Encounter for long-term (current) use of anticoagulants Both 1049 5399 4 hematopoietic darkorange1 5399, 1049 1350, 243 1350, 236 1349, 288 1350, 282 0.093 0.0351 0.00808 2.093 1.1 1.02 1.18 0.00653 0.101 0.948 0.02303 1.01 0.826 1.23 0.194 0.0979 0.0471 1.327 1.21 1 1.47 0.195 0.102 0.0559 1.253 1.22 0.995 1.48 PRS_PLINK_0.0199526231496888 FALSE 286.3 Coagulation defects complicating pregnancy or postpartum Female 52 527 4 hematopoietic darkorange1 527, 52 132, 11 132, 12 131, 9 132, 20 0.334 0.152 0.0282 1.55 1.4 1.04 1.88 0.0623 0.43 0.885 0.05313 1.06 0.458 2.47 -0.269 0.451 0.551 0.2591 0.764 0.316 1.85 0.692 0.394 0.0791 1.102 2 0.923 4.32 PRS_PLINK_0.0199526231496888 FALSE 286.4 Acquired coagulation factor deficiency Both 97 500 4 hematopoietic darkorange1 500, 97 125, 15 125, 30 125, 19 125, 33 0.222 0.115 0.0528 1.278 1.25 0.997 1.56 0.616 0.336 0.0665 1.177 1.85 0.959 3.58 0.253 0.367 0.491 0.309 1.29 0.627 2.65 0.566 0.351 0.107 0.971 1.76 0.885 3.51 PRS_PLINK_0.0199526231496888 FALSE 286.5 Hemorrhagic disorder due to intrinsic circulating anticoagulants Both 41 248 4 hematopoietic darkorange1 248, 41 62, 5 62, 13 62, 5 62, 18 0.296 0.176 0.0934 1.029 1.34 0.951 1.9 0.461 0.549 0.401 0.3964 1.59 0.54 4.65 0.207 0.636 0.744 0.1283 1.23 0.354 4.28 1.15 0.636 0.0716 1.145 3.14 0.904 10.9 PRS_PLINK_0.0199526231496888 TRUE 286.6 Defibrination syndrome Both 812 6117 4 hematopoietic darkorange1 6117, 812 1530, 176 1529, 194 1529, 224 1529, 217 0.12 0.0387 0.00198 2.704 1.13 1.04 1.22 0.137 0.111 0.216 0.6647 1.15 0.923 1.43 0.226 0.109 0.039 1.409 1.25 1.01 1.55 0.247 0.114 0.03 1.523 1.28 1.02 1.6 PRS_PLINK_0.0199526231496888 FALSE 286.7 Other and unspecified coagulation defects Both 973 7152 4 hematopoietic darkorange1 7152, 973 1788, 211 1788, 231 1788, 263 1788, 267 0.138 0.0353 9.03e-05 4.044 1.15 1.07 1.23 0.126 0.102 0.216 0.6646 1.13 0.929 1.38 0.22 0.1 0.0285 1.546 1.25 1.02 1.52 0.28 0.103 0.00678 2.169 1.32 1.08 1.62 PRS_PLINK_0.0199526231496888 FALSE 286.8 Hypercoagulable state Both 290 2319 4 hematopoietic darkorange1 2319, 290 580, 84 580, 73 579, 74 580, 58 -0.0725 0.064 0.258 0.5892 0.93 0.82 1.05 -0.135 0.17 0.426 0.3709 0.873 0.626 1.22 -0.0902 0.171 0.598 0.2232 0.914 0.653 1.28 -0.312 0.188 0.0964 1.016 0.732 0.506 1.06 PRS_PLINK_0.0199526231496888 FALSE 286.81 Primary hypercoagulable state Both 277 2255 4 hematopoietic darkorange1 2255, 277 564, 83 564, 69 563, 69 564, 55 -0.0956 0.0655 0.144 0.8407 0.909 0.799 1.03 -0.168 0.173 0.331 0.4799 0.845 0.602 1.19 -0.156 0.175 0.374 0.4271 0.856 0.607 1.21 -0.352 0.192 0.0664 1.178 0.703 0.483 1.02 PRS_PLINK_0.0199526231496888 FALSE 286.9 Abnormal coagulation profile Both 380 2335 4 hematopoietic darkorange1 2335, 380 584, 71 584, 89 583, 107 584, 113 0.206 0.0563 0.000257 3.59 1.23 1.1 1.37 0.24 0.172 0.161 0.7921 1.27 0.908 1.78 0.395 0.169 0.0192 1.717 1.48 1.07 2.07 0.422 0.173 0.0144 1.841 1.53 1.09 2.14 PRS_PLINK_0.0199526231496888 FALSE 287 Purpura and other hemorrhagic conditions Both 1018 6489 4 hematopoietic darkorange1 6489, 1018 1623, 207 1622, 253 1622, 271 1622, 286 0.155 0.035 9.87e-06 5.005 1.17 1.09 1.25 0.22 0.101 0.0297 1.528 1.25 1.02 1.52 0.269 0.101 0.008 2.097 1.31 1.07 1.6 0.396 0.103 0.000119 3.924 1.49 1.21 1.82 PRS_PLINK_0.0199526231496888 FALSE 287.1 Spontaneous ecchymoses Both 69 523 4 hematopoietic darkorange1 523, 69 131, 13 131, 12 130, 20 131, 24 0.363 0.139 0.00921 2.036 1.44 1.09 1.89 0.0764 0.408 0.851 0.06989 1.08 0.485 2.4 0.395 0.371 0.287 0.5418 1.48 0.717 3.07 0.859 0.393 0.0287 1.542 2.36 1.09 5.1 PRS_PLINK_0.0199526231496888 FALSE 287.3 Thrombocytopenia Both 941 5846 4 hematopoietic darkorange1 5846, 941 1462, 187 1461, 244 1461, 246 1462, 263 0.154 0.0363 2.27e-05 4.643 1.17 1.09 1.25 0.285 0.105 0.00662 2.179 1.33 1.08 1.63 0.268 0.107 0.0119 1.926 1.31 1.06 1.61 0.41 0.108 0.000146 3.834 1.51 1.22 1.86 PRS_PLINK_0.0199526231496888 FALSE 287.31 Primary thrombocytopenia Both 174 1374 4 hematopoietic darkorange1 1374, 174 344, 32 343, 44 343, 48 344, 49 0.16 0.0828 0.0536 1.271 1.17 0.998 1.38 0.339 0.244 0.165 0.7817 1.4 0.869 2.27 0.388 0.245 0.112 0.9489 1.47 0.913 2.38 0.448 0.25 0.0736 1.133 1.57 0.958 2.56 PRS_PLINK_0.0199526231496888 FALSE 287.32 Secondary thrombocytopenia Both 195 1284 4 hematopoietic darkorange1 1284, 195 321, 46 321, 51 321, 45 321, 53 0.107 0.0786 0.172 0.7634 1.11 0.954 1.3 0.126 0.219 0.563 0.2494 1.13 0.739 1.74 -0.023 0.226 0.919 0.03661 0.977 0.627 1.52 0.226 0.225 0.315 0.5019 1.25 0.807 1.95 PRS_PLINK_0.0199526231496888 FALSE 287.4 Qualitative platelet defects Both 37 298 4 hematopoietic darkorange1 298, 37 75, 9 74, 5 74, 9 75, 14 0.226 0.173 0.191 0.7189 1.25 0.893 1.76 -0.48 0.545 0.378 0.4222 0.619 0.212 1.8 -0.244 0.53 0.645 0.1904 0.783 0.277 2.21 0.509 0.473 0.282 0.5491 1.66 0.658 4.21 PRS_PLINK_0.0199526231496888 TRUE 288 Diseases of white blood cells Both 1487 9729 4 hematopoietic darkorange1 9729, 1487 2432, 365 2432, 341 2432, 403 2432, 378 0.0749 0.0288 0.00919 2.037 1.08 1.02 1.14 -0.0442 0.0815 0.587 0.231 0.957 0.815 1.12 0.118 0.0797 0.138 0.8596 1.13 0.963 1.32 0.0821 0.0833 0.324 0.4888 1.09 0.922 1.28 PRS_PLINK_0.0199526231496888 FALSE 288.1 Decreased white blood cell count Both 555 4045 4 hematopoietic darkorange1 4045, 555 1012, 131 1011, 146 1011, 160 1011, 118 -0.024 0.0469 0.609 0.2157 0.976 0.89 1.07 0.115 0.129 0.371 0.4307 1.12 0.872 1.44 0.188 0.128 0.142 0.8489 1.21 0.939 1.55 -0.0982 0.14 0.482 0.317 0.906 0.689 1.19 PRS_PLINK_0.0199526231496888 FALSE 288.11 Neutropenia Both 386 2768 4 hematopoietic darkorange1 2768, 386 692, 92 692, 106 692, 108 692, 80 -0.0308 0.0564 0.586 0.2322 0.97 0.868 1.08 0.14 0.153 0.359 0.4446 1.15 0.853 1.55 0.149 0.154 0.332 0.4789 1.16 0.859 1.57 -0.153 0.169 0.366 0.4368 0.858 0.617 1.2 PRS_PLINK_0.0199526231496888 FALSE 288.2 Elevated white blood cell count Both 1234 9108 4 hematopoietic darkorange1 9108, 1234 2276, 300 2277, 276 2277, 332 2277, 326 0.0938 0.0313 0.00271 2.567 1.1 1.03 1.17 -0.0562 0.0893 0.529 0.2765 0.945 0.793 1.13 0.128 0.0868 0.14 0.8551 1.14 0.959 1.35 0.125 0.0899 0.166 0.7804 1.13 0.95 1.35 PRS_PLINK_0.0199526231496888 FALSE 288.3 Eosinophilia Both 69 520 4 hematopoietic darkorange1 520, 69 130, 20 130, 16 130, 17 130, 16 0.0778 0.133 0.558 0.2533 1.08 0.833 1.4 -0.197 0.352 0.575 0.2402 0.821 0.411 1.64 -0.0753 0.359 0.834 0.07888 0.927 0.459 1.87 -0.125 0.378 0.741 0.1303 0.882 0.42 1.85 PRS_PLINK_0.0199526231496888 FALSE 289 Other diseases of blood and blood-forming organs Both 560 4595 4 hematopoietic darkorange1 4595, 560 1148, 116 1149, 139 1148, 149 1149, 156 0.128 0.0471 0.00635 2.197 1.14 1.04 1.25 0.198 0.132 0.134 0.8717 1.22 0.941 1.58 0.281 0.133 0.0345 1.462 1.32 1.02 1.72 0.333 0.137 0.0148 1.829 1.39 1.07 1.82 PRS_PLINK_0.0199526231496888 FALSE 289.3 Personal history of diseases of blood and blood-forming organs Both 300 2671 4 hematopoietic darkorange1 2671, 300 668, 62 668, 75 667, 86 668, 77 0.0852 0.0641 0.184 0.7359 1.09 0.96 1.23 0.195 0.179 0.276 0.5597 1.22 0.856 1.72 0.312 0.178 0.0787 1.104 1.37 0.965 1.94 0.171 0.187 0.361 0.4425 1.19 0.822 1.71 PRS_PLINK_0.0199526231496888 FALSE 289.4 Lymphadenitis Both 1163 9256 4 hematopoietic darkorange1 9256, 1163 2313, 289 2314, 275 2314, 303 2314, 296 0.025 0.0323 0.438 0.3581 1.03 0.962 1.09 -0.0365 0.0896 0.684 0.1648 0.964 0.809 1.15 0.0273 0.0889 0.759 0.1198 1.03 0.863 1.22 0.051 0.0922 0.58 0.2364 1.05 0.878 1.26 PRS_PLINK_0.0199526231496888 FALSE 289.5 Diseases of spleen Both 129 945 4 hematopoietic darkorange1 945, 129 237, 25 236, 42 236, 27 236, 35 0.0758 0.0941 0.421 0.376 1.08 0.897 1.3 0.477 0.268 0.0753 1.123 1.61 0.952 2.73 -0.0271 0.293 0.926 0.03316 0.973 0.548 1.73 0.299 0.29 0.302 0.5196 1.35 0.764 2.38 PRS_PLINK_0.0199526231496888 FALSE 289.8 Polycythemia, secondary Both 49 517 4 hematopoietic darkorange1 517, 49 130, 10 129, 9 129, 16 129, 14 0.203 0.153 0.184 0.7349 1.22 0.908 1.65 -0.282 0.454 0.535 0.272 0.754 0.31 1.84 0.306 0.413 0.459 0.3384 1.36 0.605 3.05 0.245 0.422 0.562 0.2504 1.28 0.559 2.92 PRS_PLINK_0.0199526231496888 TRUE 289.9 Abnormality of red blood cells Both 116 909 4 hematopoietic darkorange1 909, 116 228, 21 227, 28 227, 26 227, 41 0.294 0.103 0.00413 2.384 1.34 1.1 1.64 0.391 0.304 0.198 0.7036 1.48 0.815 2.68 0.402 0.31 0.195 0.7093 1.49 0.814 2.74 0.773 0.297 0.00917 2.038 2.17 1.21 3.87 PRS_PLINK_0.0199526231496888 FALSE 290 Delirium dementia and amnestic and other cognitive disorders Both 296 2095 5 mental disorders magenta 2095, 296 524, 66 524, 76 523, 69 524, 85 0.0696 0.0628 0.267 0.5729 1.07 0.948 1.21 0.135 0.179 0.451 0.3458 1.14 0.806 1.62 0.0869 0.185 0.638 0.195 1.09 0.759 1.57 0.254 0.182 0.163 0.7877 1.29 0.902 1.84 PRS_PLINK_0.0199526231496888 FALSE 290.1 Dementias Both 92 785 5 mental disorders magenta 785, 92 197, 22 196, 23 196, 17 196, 30 0.0426 0.111 0.702 0.1539 1.04 0.839 1.3 0.0851 0.311 0.784 0.1056 1.09 0.592 2 -0.155 0.336 0.644 0.1912 0.856 0.443 1.65 0.309 0.307 0.315 0.5015 1.36 0.746 2.49 PRS_PLINK_0.0199526231496888 FALSE 290.11 Alzheimer's disease Both 19 209 5 mental disorders magenta 209, 19 53, 5 52, 4 52, 2 52, 8 -0.0145 0.262 0.956 0.01957 0.986 0.59 1.65 -0.285 0.653 0.663 0.1788 0.752 0.209 2.71 -0.59 0.722 0.413 0.3835 0.554 0.135 2.28 0.626 0.653 0.338 0.4714 1.87 0.52 6.73 PRS_PLINK_0.0199526231496888 TRUE 290.12 Dementia with cerebral degenerations Both 16 126 5 mental disorders magenta 126, 16 32, 2 31, 7 31, 2 32, 5 0.147 0.293 0.616 0.2106 1.16 0.652 2.06 1.06 0.751 0.159 0.7989 2.88 0.661 12.5 0.273 0.873 0.755 0.1222 1.31 0.237 7.27 0.677 0.83 0.415 0.3824 1.97 0.387 10 PRS_PLINK_0.0199526231496888 TRUE 290.13 Senile dementia Both 55 435 5 mental disorders magenta 435, 55 109, 14 109, 13 108, 13 109, 15 -0.0273 0.141 0.847 0.07232 0.973 0.738 1.28 -0.125 0.409 0.76 0.1194 0.882 0.396 1.97 -0.0146 0.409 0.971 0.01258 0.985 0.442 2.2 -0.00358 0.401 0.993 0.003109 0.996 0.454 2.19 PRS_PLINK_0.0199526231496888 FALSE 290.16 Vascular dementia Both 9 110 5 mental disorders magenta 110, 9 28, 0 27, 1 27, 2 28, 6 0.816 0.366 0.0257 1.589 2.26 1.1 4.63 1.29 1.19 0.28 0.5527 3.62 0.35 37.5 1.51 1.15 0.191 0.7188 4.52 0.471 43.4 2.32 1.39 0.0965 1.015 10.1 0.66 155 PRS_PLINK_0.0199526231496888 TRUE 290.2 Delirium due to conditions classified elsewhere Both 201 1391 5 mental disorders magenta 1391, 201 348, 41 348, 55 347, 48 348, 57 0.0676 0.0752 0.369 0.4331 1.07 0.923 1.24 0.255 0.22 0.246 0.6085 1.29 0.839 1.98 0.176 0.228 0.438 0.3586 1.19 0.764 1.86 0.291 0.226 0.197 0.7049 1.34 0.86 2.08 PRS_PLINK_0.0199526231496888 FALSE 290.3 Other persistent mental disorders due to conditions classified elsewhere Both 196 1856 5 mental disorders magenta 1856, 196 464, 53 464, 43 464, 42 464, 58 -0.0228 0.0764 0.765 0.1162 0.977 0.842 1.14 -0.18 0.213 0.398 0.4003 0.835 0.551 1.27 -0.243 0.216 0.26 0.5855 0.784 0.513 1.2 0.0493 0.208 0.812 0.09028 1.05 0.699 1.58 PRS_PLINK_0.0199526231496888 FALSE 291 Other specified nonpsychotic and/or transient mental disorders Both 746 6631 5 mental disorders magenta 6631, 746 1657, 172 1658, 177 1657, 172 1658, 225 0.0926 0.0398 0.0199 1.7 1.1 1.01 1.19 0.044 0.113 0.697 0.1568 1.04 0.837 1.3 0.00798 0.115 0.945 0.02473 1.01 0.805 1.26 0.32 0.113 0.00459 2.338 1.38 1.1 1.72 PRS_PLINK_0.0199526231496888 FALSE 291.1 Transient mental disorders due to conditions classified elsewhere Both 86 789 5 mental disorders magenta 789, 86 198, 21 197, 23 197, 19 197, 23 -0.03 0.119 0.8 0.09682 0.97 0.769 1.22 0.0934 0.31 0.763 0.1175 1.1 0.598 2.01 -0.115 0.325 0.723 0.1407 0.891 0.472 1.68 0.226 0.327 0.489 0.3107 1.25 0.66 2.38 PRS_PLINK_0.0199526231496888 FALSE 291.4 Specific nonpsychotic mental disorders due to brain damage Both 139 1263 5 mental disorders magenta 1263, 139 316, 27 316, 38 315, 36 316, 38 0.133 0.0934 0.154 0.8134 1.14 0.951 1.37 0.359 0.258 0.165 0.7826 1.43 0.863 2.37 0.254 0.264 0.338 0.4717 1.29 0.767 2.16 0.317 0.277 0.252 0.5987 1.37 0.798 2.36 PRS_PLINK_0.0199526231496888 FALSE 291.8 Alteration of consciousness Both 563 5008 5 mental disorders magenta 5008, 563 1251, 134 1252, 130 1252, 127 1252, 172 0.0762 0.0453 0.0927 1.033 1.08 0.987 1.18 -0.0281 0.13 0.828 0.08175 0.972 0.754 1.25 -0.043 0.132 0.745 0.1281 0.958 0.739 1.24 0.25 0.128 0.0514 1.289 1.28 0.999 1.65 PRS_PLINK_0.0199526231496888 FALSE 292 Neurological disorders Both 1477 10442 5 mental disorders magenta 10442, 1477 2610, 373 2610, 359 2610, 365 2611, 380 0.0456 0.0287 0.112 0.951 1.05 0.989 1.11 -0.00354 0.0798 0.965 0.01567 0.996 0.852 1.17 0.00149 0.0805 0.985 0.006457 1 0.855 1.17 0.0914 0.0822 0.267 0.5743 1.1 0.933 1.29 PRS_PLINK_0.0199526231496888 FALSE 292.1 Aphasia/speech disturbance Both 485 4507 5 mental disorders magenta 4507, 485 1127, 127 1127, 114 1126, 126 1127, 118 0.00608 0.0489 0.901 0.0453 1.01 0.914 1.11 -0.0743 0.136 0.585 0.2325 0.928 0.711 1.21 -0.0281 0.135 0.835 0.07841 0.972 0.747 1.27 -0.0809 0.14 0.562 0.2499 0.922 0.701 1.21 PRS_PLINK_0.0199526231496888 FALSE 292.11 Aphasia Both 164 1507 5 mental disorders magenta 1507, 164 377, 33 377, 42 376, 38 377, 51 0.15 0.0838 0.0736 1.133 1.16 0.986 1.37 0.265 0.24 0.27 0.5678 1.3 0.814 2.09 0.113 0.249 0.649 0.1877 1.12 0.688 1.82 0.389 0.239 0.103 0.9858 1.48 0.924 2.36 PRS_PLINK_0.0199526231496888 FALSE 292.12 Symbolic dysfunction Both 36 507 5 mental disorders magenta 507, 36 127, 7 127, 9 126, 11 127, 9 0.127 0.175 0.467 0.331 1.14 0.806 1.6 0.265 0.483 0.583 0.2344 1.3 0.506 3.36 0.503 0.47 0.284 0.5463 1.65 0.659 4.15 0.274 0.515 0.595 0.2256 1.32 0.479 3.61 PRS_PLINK_0.0199526231496888 TRUE 292.2 Mild cognitive impairment Both 84 647 5 mental disorders magenta 647, 84 162, 20 162, 17 161, 18 162, 29 0.00946 0.119 0.937 0.02836 1.01 0.799 1.28 -0.154 0.337 0.647 0.1893 0.857 0.443 1.66 -0.171 0.341 0.616 0.2104 0.843 0.432 1.65 0.377 0.321 0.239 0.6215 1.46 0.778 2.73 PRS_PLINK_0.0199526231496888 FALSE 292.3 Memory loss Both 434 4138 5 mental disorders magenta 4138, 434 1034, 113 1034, 108 1034, 94 1035, 119 -0.00287 0.0518 0.956 0.01964 0.997 0.901 1.1 -0.0291 0.141 0.837 0.07748 0.971 0.736 1.28 -0.131 0.148 0.378 0.4231 0.877 0.656 1.17 0.0838 0.145 0.564 0.249 1.09 0.818 1.45 PRS_PLINK_0.0199526231496888 FALSE 292.4 Altered mental status Both 643 4976 5 mental disorders magenta 4976, 643 1244, 158 1244, 152 1244, 151 1244, 182 0.0607 0.0424 0.153 0.8155 1.06 0.978 1.15 -0.0371 0.121 0.759 0.1199 0.964 0.761 1.22 -0.0174 0.122 0.887 0.05219 0.983 0.774 1.25 0.17 0.121 0.158 0.8018 1.19 0.936 1.5 PRS_PLINK_0.0199526231496888 FALSE 292.5 Transient alteration of awareness Both 120 1030 5 mental disorders magenta 1030, 120 258, 38 257, 30 257, 24 258, 28 -0.118 0.102 0.248 0.6048 0.889 0.728 1.09 -0.209 0.259 0.418 0.3789 0.811 0.489 1.35 -0.447 0.277 0.107 0.9716 0.64 0.372 1.1 -0.362 0.277 0.19 0.7208 0.696 0.405 1.2 PRS_PLINK_0.0199526231496888 FALSE 292.6 Hallucinations Both 66 520 5 mental disorders magenta 520, 66 130, 11 130, 19 130, 20 130, 16 0.124 0.131 0.345 0.4625 1.13 0.876 1.46 0.615 0.395 0.12 0.9225 1.85 0.853 4.01 0.444 0.403 0.271 0.5664 1.56 0.707 3.44 0.481 0.424 0.256 0.5911 1.62 0.705 3.71 PRS_PLINK_0.0199526231496888 FALSE 293 Symptoms involving head and neck Both 121 1202 5 mental disorders magenta 1202, 121 301, 25 300, 37 300, 28 301, 31 0.0223 0.1 0.824 0.08382 1.02 0.84 1.25 0.35 0.266 0.188 0.7254 1.42 0.842 2.39 0.0697 0.282 0.805 0.09435 1.07 0.617 1.86 0.152 0.289 0.6 0.2215 1.16 0.66 2.05 PRS_PLINK_0.0199526231496888 FALSE 293.1 Swelling, mass, or lump in head and neck [Space-occupying lesion, intracranial NOS] Both 1095 10433 5 mental disorders magenta 10433, 1095 2608, 270 2608, 253 2608, 276 2608, 296 0.0248 0.0328 0.449 0.3479 1.03 0.961 1.09 -0.0658 0.0922 0.475 0.3231 0.936 0.781 1.12 0.02 0.0915 0.827 0.08253 1.02 0.853 1.22 0.0959 0.0928 0.301 0.5208 1.1 0.918 1.32 PRS_PLINK_0.0199526231496888 FALSE 295 Schizophrenia and other psychotic disorders Both 248 1910 5 mental disorders magenta 1910, 248 478, 63 477, 62 477, 65 478, 58 -0.00692 0.0693 0.92 0.03598 0.993 0.867 1.14 0.0374 0.192 0.845 0.07304 1.04 0.713 1.51 -0.00326 0.194 0.987 0.005867 0.997 0.682 1.46 -0.0206 0.203 0.919 0.03671 0.98 0.658 1.46 PRS_PLINK_0.0199526231496888 FALSE 295.1 Schizophrenia Both 42 436 5 mental disorders magenta 436, 42 109, 14 109, 11 109, 11 109, 6 -0.181 0.167 0.278 0.556 0.835 0.602 1.16 -0.296 0.426 0.487 0.3123 0.744 0.323 1.71 -0.258 0.438 0.556 0.2551 0.773 0.327 1.82 -0.742 0.499 0.137 0.8623 0.476 0.179 1.27 PRS_PLINK_0.0199526231496888 TRUE 295.2 Paranoid disorders Both 30 255 5 mental disorders magenta 255, 30 64, 7 64, 5 63, 9 64, 9 0.292 0.213 0.17 0.769 1.34 0.882 2.03 -0.0909 0.585 0.877 0.05722 0.913 0.29 2.88 0.134 0.6 0.824 0.0842 1.14 0.353 3.7 0.791 0.605 0.192 0.7177 2.21 0.673 7.22 PRS_PLINK_0.0199526231496888 TRUE 295.3 Psychosis Both 198 1529 5 mental disorders magenta 1529, 198 383, 46 382, 49 382, 54 382, 49 0.00791 0.0775 0.919 0.03682 1.01 0.866 1.17 0.124 0.218 0.571 0.2435 1.13 0.738 1.74 0.0838 0.218 0.701 0.1543 1.09 0.709 1.67 0.0803 0.229 0.726 0.1389 1.08 0.691 1.7 PRS_PLINK_0.0199526231496888 FALSE 296 Mood disorders Both 4648 5553 5 mental disorders magenta 5553, 4648 1389, 1117 1388, 1166 1388, 1193 1388, 1171 0.0341 0.0209 0.102 0.9899 1.03 0.993 1.08 0.0336 0.0584 0.566 0.2473 1.03 0.922 1.16 0.0549 0.0586 0.349 0.4576 1.06 0.942 1.19 0.0533 0.0608 0.38 0.4197 1.05 0.936 1.19 PRS_PLINK_0.0199526231496888 FALSE 296.1 Bipolar Both 451 3697 5 mental disorders magenta 3697, 451 925, 101 924, 114 924, 102 924, 134 0.0735 0.0515 0.154 0.8126 1.08 0.973 1.19 0.0955 0.146 0.514 0.2893 1.1 0.826 1.47 0.000621 0.152 0.997 0.001418 1 0.743 1.35 0.271 0.148 0.067 1.174 1.31 0.981 1.75 PRS_PLINK_0.0199526231496888 FALSE 296.2 Depression Both 4507 5550 5 mental disorders magenta 5550, 4507 1388, 1094 1387, 1119 1387, 1156 1388, 1137 0.0339 0.0211 0.108 0.9677 1.03 0.993 1.08 0.0147 0.059 0.803 0.09522 1.01 0.904 1.14 0.0427 0.0591 0.47 0.3279 1.04 0.93 1.17 0.0448 0.0612 0.464 0.3336 1.05 0.928 1.18 PRS_PLINK_0.0199526231496888 FALSE 296.22 Major depressive disorder Both 4189 5551 5 mental disorders magenta 5551, 4189 1388, 1030 1388, 1038 1387, 1077 1388, 1043 0.0281 0.0215 0.191 0.7192 1.03 0.986 1.07 -0.00366 0.0602 0.952 0.02155 0.996 0.885 1.12 0.0367 0.0602 0.542 0.266 1.04 0.922 1.17 0.0183 0.0625 0.77 0.1134 1.02 0.901 1.15 PRS_PLINK_0.0199526231496888 FALSE 297 Suicidal ideation or attempt Both 354 2946 5 mental disorders magenta 2946, 354 737, 84 736, 92 736, 89 737, 89 0.0572 0.0601 0.342 0.4662 1.06 0.941 1.19 0.0602 0.164 0.714 0.1465 1.06 0.77 1.46 0.0174 0.17 0.919 0.03686 1.02 0.729 1.42 0.042 0.175 0.81 0.09131 1.04 0.74 1.47 PRS_PLINK_0.0199526231496888 FALSE 297.1 Suicidal ideation Both 294 2383 5 mental disorders magenta 2383, 294 596, 66 596, 80 595, 73 596, 75 0.0786 0.0665 0.237 0.6244 1.08 0.95 1.23 0.163 0.18 0.364 0.4384 1.18 0.827 1.68 0.0419 0.189 0.825 0.08351 1.04 0.719 1.51 0.096 0.193 0.619 0.2081 1.1 0.754 1.61 PRS_PLINK_0.0199526231496888 FALSE 297.2 Suicide or self-inflicted injury Both 114 967 5 mental disorders magenta 967, 114 242, 30 242, 23 241, 32 242, 29 0.0751 0.102 0.463 0.3345 1.08 0.882 1.32 -0.307 0.299 0.304 0.5174 0.735 0.409 1.32 0.175 0.281 0.535 0.2719 1.19 0.686 2.07 -0.115 0.297 0.699 0.1554 0.891 0.498 1.6 PRS_PLINK_0.0199526231496888 FALSE 300 Anxiety disorders Both 4814 5550 5 mental disorders magenta 5550, 4814 1388, 1152 1387, 1211 1387, 1247 1388, 1203 0.0296 0.0208 0.154 0.8121 1.03 0.989 1.07 0.0499 0.058 0.39 0.4094 1.05 0.938 1.18 0.0809 0.0581 0.163 0.7866 1.08 0.968 1.21 0.0502 0.0605 0.406 0.391 1.05 0.934 1.18 PRS_PLINK_0.0199526231496888 FALSE 300.1 Anxiety disorder Both 4556 5552 5 mental disorders magenta 5552, 4556 1388, 1091 1388, 1143 1388, 1177 1388, 1144 0.0303 0.0211 0.15 0.8235 1.03 0.989 1.07 0.0424 0.0589 0.471 0.3267 1.04 0.93 1.17 0.0737 0.0589 0.211 0.676 1.08 0.959 1.21 0.0459 0.0613 0.454 0.3427 1.05 0.928 1.18 PRS_PLINK_0.0199526231496888 FALSE 300.11 Generalized anxiety disorder Both 1803 5462 5 mental disorders magenta 5462, 1803 1366, 442 1365, 448 1365, 464 1366, 449 0.014 0.029 0.629 0.2013 1.01 0.958 1.07 -0.0101 0.0807 0.901 0.0454 0.99 0.845 1.16 0.0244 0.0808 0.763 0.1176 1.02 0.875 1.2 0.00194 0.0844 0.982 0.008015 1 0.849 1.18 PRS_PLINK_0.0199526231496888 FALSE 300.12 Agorophobia, social phobia, and panic disorder Both 467 3721 5 mental disorders magenta 3721, 467 931, 115 930, 109 930, 124 930, 119 0.0434 0.0537 0.419 0.3779 1.04 0.94 1.16 -0.0408 0.149 0.785 0.1051 0.96 0.716 1.29 0.107 0.147 0.468 0.3295 1.11 0.834 1.48 0.0889 0.155 0.566 0.2475 1.09 0.807 1.48 PRS_PLINK_0.0199526231496888 FALSE 300.13 Phobia Both 306 2894 5 mental disorders magenta 2894, 306 724, 78 723, 70 723, 87 724, 71 0.0217 0.0647 0.737 0.1324 1.02 0.9 1.16 -0.106 0.179 0.556 0.255 0.9 0.633 1.28 0.0662 0.177 0.708 0.1501 1.07 0.756 1.51 -0.053 0.193 0.784 0.1059 0.948 0.65 1.38 PRS_PLINK_0.0199526231496888 FALSE 300.3 Obsessive-compulsive disorders Both 112 1087 5 mental disorders magenta 1087, 112 272, 32 272, 18 271, 31 272, 31 0.0545 0.102 0.595 0.2258 1.06 0.864 1.29 -0.504 0.313 0.107 0.972 0.604 0.327 1.11 0.0935 0.28 0.738 0.1319 1.1 0.635 1.9 0.106 0.286 0.711 0.1481 1.11 0.635 1.95 PRS_PLINK_0.0199526231496888 FALSE 300.4 Dysthymic disorder Both 796 4664 5 mental disorders magenta 4664, 796 1166, 197 1166, 227 1166, 192 1166, 180 -0.0232 0.0401 0.562 0.2501 0.977 0.903 1.06 0.13 0.108 0.229 0.641 1.14 0.921 1.41 -0.00459 0.113 0.968 0.01433 0.995 0.798 1.24 -0.0849 0.119 0.474 0.3241 0.919 0.728 1.16 PRS_PLINK_0.0199526231496888 FALSE 300.8 Acute reaction to stress Both 158 1471 5 mental disorders magenta 1471, 158 368, 46 368, 32 367, 41 368, 39 -0.0642 0.0876 0.464 0.3335 0.938 0.79 1.11 -0.332 0.241 0.169 0.7729 0.717 0.447 1.15 -0.121 0.233 0.605 0.2184 0.886 0.561 1.4 -0.081 0.242 0.738 0.1321 0.922 0.574 1.48 PRS_PLINK_0.0199526231496888 FALSE 300.9 Posttraumatic stress disorder Both 297 2710 5 mental disorders magenta 2710, 297 678, 63 677, 79 677, 71 678, 84 0.0965 0.0646 0.135 0.8686 1.1 0.97 1.25 0.222 0.178 0.214 0.6688 1.25 0.88 1.77 0.00628 0.189 0.974 0.01166 1.01 0.695 1.46 0.224 0.185 0.227 0.6432 1.25 0.87 1.8 PRS_PLINK_0.0199526231496888 FALSE 301 Personality disorders Both 184 1671 5 mental disorders magenta 1671, 184 418, 38 418, 46 417, 49 418, 51 0.107 0.0816 0.19 0.7222 1.11 0.948 1.31 0.2 0.231 0.385 0.4141 1.22 0.777 1.92 0.233 0.233 0.317 0.4989 1.26 0.8 1.99 0.226 0.241 0.347 0.4598 1.25 0.782 2.01 PRS_PLINK_0.0199526231496888 FALSE 301.2 Antisocial/borderline personality disorder Both 104 927 5 mental disorders magenta 927, 104 232, 26 232, 26 231, 27 232, 25 -0.0536 0.109 0.623 0.2056 0.948 0.765 1.17 0.0568 0.295 0.847 0.07189 1.06 0.593 1.89 0.0436 0.299 0.884 0.05347 1.04 0.581 1.88 -0.22 0.315 0.486 0.3136 0.803 0.433 1.49 PRS_PLINK_0.0199526231496888 FALSE 302 Sexual and gender identity disorders Both 702 3343 5 mental disorders magenta 3343, 702 836, 174 836, 188 835, 170 836, 170 0.00169 0.0434 0.969 0.01373 1 0.92 1.09 0.106 0.119 0.373 0.4282 1.11 0.88 1.41 0.0436 0.123 0.724 0.1402 1.04 0.82 1.33 0.0608 0.128 0.634 0.1983 1.06 0.828 1.36 PRS_PLINK_0.0199526231496888 FALSE 302.1 Decreased libido Both 130 1124 5 mental disorders magenta 1124, 130 281, 38 281, 32 281, 29 281, 31 -0.0468 0.0994 0.638 0.1954 0.954 0.785 1.16 -0.103 0.262 0.695 0.1581 0.902 0.54 1.51 -0.165 0.27 0.54 0.2675 0.848 0.5 1.44 -0.0944 0.274 0.73 0.1364 0.91 0.532 1.56 PRS_PLINK_0.0199526231496888 FALSE 303 Psychogenic and somatoform disorders Both 1651 5340 5 mental disorders magenta 5340, 1651 1335, 466 1335, 395 1335, 418 1335, 372 -0.0267 0.0296 0.367 0.4353 0.974 0.919 1.03 -0.148 0.0807 0.0668 1.175 0.862 0.736 1.01 -0.0873 0.0807 0.279 0.554 0.916 0.782 1.07 -0.147 0.0858 0.0873 1.059 0.864 0.73 1.02 PRS_PLINK_0.0199526231496888 FALSE 303.1 Dissociative disorder Both 53 541 5 mental disorders magenta 541, 53 136, 14 135, 11 135, 12 135, 16 0.0386 0.151 0.798 0.09823 1.04 0.774 1.4 -0.284 0.41 0.488 0.3114 0.752 0.337 1.68 -0.0953 0.41 0.816 0.08806 0.909 0.407 2.03 0.179 0.402 0.656 0.1833 1.2 0.544 2.63 PRS_PLINK_0.0199526231496888 FALSE 303.3 Psychogenic disorder Both 1545 5309 5 mental disorders magenta 5309, 1545 1328, 440 1327, 371 1327, 386 1327, 348 -0.0316 0.0304 0.3 0.5235 0.969 0.913 1.03 -0.158 0.0828 0.0556 1.255 0.853 0.726 1 -0.111 0.083 0.18 0.7455 0.895 0.76 1.05 -0.159 0.088 0.0704 1.152 0.853 0.718 1.01 PRS_PLINK_0.0199526231496888 FALSE 303.31 Gastrointestinal malfunction arising from mental factors Both 134 1358 5 mental disorders magenta 1358, 134 340, 47 339, 30 339, 29 340, 28 -0.203 0.0898 0.0236 1.627 0.816 0.684 0.973 -0.379 0.245 0.122 0.9137 0.684 0.423 1.11 -0.447 0.251 0.0744 1.128 0.639 0.391 1.05 -0.446 0.263 0.0901 1.045 0.64 0.382 1.07 PRS_PLINK_0.0199526231496888 FALSE 303.4 Somatoform disorder Both 394 3607 5 mental disorders magenta 3607, 394 902, 109 902, 100 901, 92 902, 93 -0.0586 0.0546 0.284 0.5469 0.943 0.847 1.05 -0.0711 0.148 0.63 0.2004 0.931 0.697 1.24 -0.129 0.153 0.399 0.3985 0.879 0.651 1.19 -0.11 0.157 0.483 0.3159 0.895 0.658 1.22 PRS_PLINK_0.0199526231496888 FALSE 304 Adjustment reaction Both 1136 5454 5 mental disorders magenta 5454, 1136 1364, 290 1363, 284 1363, 279 1364, 283 0.0282 0.034 0.407 0.3902 1.03 0.962 1.1 -0.0249 0.0937 0.791 0.1021 0.975 0.812 1.17 -0.0551 0.095 0.561 0.2507 0.946 0.786 1.14 -0.00442 0.0985 0.964 0.01583 0.996 0.821 1.21 PRS_PLINK_0.0199526231496888 FALSE 305.2 Eating disorder Both 255 2912 5 mental disorders magenta 2912, 255 728, 65 728, 66 728, 59 728, 65 0.0203 0.0682 0.766 0.1159 1.02 0.893 1.17 0.0109 0.183 0.953 0.02111 1.01 0.706 1.45 -0.0355 0.191 0.853 0.06913 0.965 0.663 1.4 0.126 0.194 0.518 0.2858 1.13 0.775 1.66 PRS_PLINK_0.0199526231496888 FALSE 306 Other mental disorder Both 643 4267 5 mental disorders magenta 4267, 643 1067, 155 1067, 167 1066, 161 1067, 159 0.0365 0.0443 0.41 0.3869 1.04 0.951 1.13 0.0948 0.123 0.44 0.357 1.1 0.865 1.4 0.0675 0.125 0.589 0.2298 1.07 0.837 1.37 0.0521 0.129 0.687 0.163 1.05 0.818 1.36 PRS_PLINK_0.0199526231496888 FALSE 306.1 Mental disorders durring/after pregnancy Female 344 1818 5 mental disorders magenta 1818, 344 455, 89 454, 89 454, 78 455, 88 0.029 0.0606 0.633 0.1989 1.03 0.914 1.16 1.39e-05 0.168 1 2.865e-05 1 0.719 1.39 -0.0604 0.175 0.73 0.1367 0.941 0.668 1.33 0.0256 0.178 0.886 0.05279 1.03 0.724 1.45 PRS_PLINK_0.0199526231496888 FALSE 306.9 Tension headache Both 267 2524 5 mental disorders magenta 2524, 267 631, 72 631, 73 631, 59 631, 62 -0.0768 0.0665 0.248 0.6054 0.926 0.813 1.06 0.0116 0.176 0.948 0.02331 1.01 0.716 1.43 -0.174 0.187 0.354 0.4516 0.841 0.583 1.21 -0.17 0.191 0.373 0.4286 0.844 0.581 1.23 PRS_PLINK_0.0199526231496888 FALSE 312 Conduct disorders Both 82 728 5 mental disorders magenta 728, 82 182, 20 182, 19 182, 22 182, 21 0.0251 0.114 0.825 0.0836 1.03 0.821 1.28 -0.0598 0.328 0.855 0.06792 0.942 0.495 1.79 0.0926 0.32 0.772 0.1121 1.1 0.586 2.05 0.0229 0.34 0.946 0.02402 1.02 0.526 1.99 PRS_PLINK_0.0199526231496888 FALSE 312.3 Impulse control disorder Both 24 244 5 mental disorders magenta 244, 24 61, 7 61, 4 61, 7 61, 6 -0.00281 0.208 0.989 0.004707 0.997 0.664 1.5 -0.505 0.586 0.388 0.411 0.603 0.192 1.9 0.108 0.532 0.839 0.07627 1.11 0.392 3.16 0.164 0.596 0.783 0.1065 1.18 0.367 3.79 PRS_PLINK_0.0199526231496888 TRUE 313 Pervasive developmental disorders Both 600 5151 5 mental disorders magenta 5151, 600 1287, 154 1288, 141 1287, 163 1288, 142 -0.0352 0.0454 0.438 0.3589 0.965 0.883 1.06 -0.0885 0.123 0.474 0.3247 0.915 0.719 1.17 0.0189 0.121 0.876 0.05746 1.02 0.804 1.29 -0.0741 0.129 0.565 0.2481 0.929 0.721 1.2 PRS_PLINK_0.0199526231496888 FALSE 313.1 Attention deficit hyperactivity disorder Both 545 4684 5 mental disorders magenta 4684, 545 1170, 138 1171, 133 1171, 147 1171, 127 -0.0351 0.0474 0.459 0.3378 0.966 0.88 1.06 -0.0394 0.129 0.76 0.1194 0.961 0.747 1.24 0.0159 0.128 0.901 0.0453 1.02 0.791 1.31 -0.0852 0.136 0.53 0.2756 0.918 0.704 1.2 PRS_PLINK_0.0199526231496888 FALSE 313.2 Tics and stuttering Both 20 229 5 mental disorders magenta 229, 20 58, 6 57, 1 57, 8 57, 5 0.0429 0.257 0.867 0.0618 1.04 0.631 1.73 -1.07 0.805 0.184 0.7355 0.343 0.0709 1.66 0.258 0.616 0.676 0.1704 1.29 0.387 4.33 -0.0117 0.625 0.985 0.006559 0.988 0.291 3.36 PRS_PLINK_0.0199526231496888 TRUE 313.3 Autism Both 29 249 5 mental disorders magenta 249, 29 63, 6 62, 6 62, 9 62, 8 0.131 0.191 0.492 0.3084 1.14 0.785 1.66 0.178 0.589 0.763 0.1175 1.19 0.377 3.79 0.434 0.551 0.432 0.3649 1.54 0.524 4.54 0.491 0.576 0.394 0.4048 1.63 0.528 5.06 PRS_PLINK_0.0199526231496888 TRUE 315 Develomental delays and disorders Both 210 1783 5 mental disorders magenta 1783, 210 446, 73 446, 46 445, 48 446, 43 -0.234 0.0753 0.00192 2.718 0.792 0.683 0.918 -0.459 0.199 0.0214 1.669 0.632 0.428 0.934 -0.417 0.2 0.0372 1.429 0.659 0.445 0.976 -0.605 0.211 0.00419 2.378 0.546 0.361 0.826 PRS_PLINK_0.0199526231496888 FALSE 315.1 Learning disorder Both 37 314 5 mental disorders magenta 314, 37 79, 11 78, 8 78, 13 79, 5 -0.11 0.181 0.542 0.2661 0.895 0.628 1.28 -0.2 0.477 0.676 0.1704 0.819 0.321 2.09 0.224 0.435 0.606 0.2175 1.25 0.534 2.93 -0.752 0.544 0.167 0.7775 0.472 0.162 1.37 PRS_PLINK_0.0199526231496888 TRUE 315.2 Speech and language disorder Both 75 660 5 mental disorders magenta 660, 75 165, 26 165, 17 165, 17 165, 15 -0.197 0.13 0.131 0.8823 0.822 0.637 1.06 -0.355 0.33 0.282 0.5504 0.701 0.367 1.34 -0.405 0.331 0.221 0.6548 0.667 0.348 1.28 -0.498 0.354 0.16 0.7967 0.607 0.303 1.22 PRS_PLINK_0.0199526231496888 FALSE 316 Substance addiction and disorders Both 1105 8841 5 mental disorders magenta 8841, 1105 2211, 282 2210, 258 2210, 278 2210, 286 0.0241 0.0327 0.461 0.3359 1.02 0.961 1.09 -0.0894 0.0917 0.329 0.4825 0.914 0.764 1.09 -0.0356 0.0916 0.698 0.1563 0.965 0.807 1.15 0.0287 0.0933 0.758 0.1203 1.03 0.857 1.24 PRS_PLINK_0.0199526231496888 FALSE 316.1 Polyneuropathy due to drugs Both 179 1581 5 mental disorders magenta 1581, 179 396, 59 395, 34 395, 52 395, 34 -0.183 0.0829 0.027 1.568 0.832 0.708 0.979 -0.562 0.227 0.0132 1.88 0.57 0.366 0.889 -0.238 0.21 0.258 0.5887 0.788 0.522 1.19 -0.51 0.235 0.03 1.523 0.6 0.379 0.952 PRS_PLINK_0.0199526231496888 FALSE 317 Alcohol-related disorders Both 672 5471 5 mental disorders magenta 5471, 672 1368, 144 1368, 186 1367, 177 1368, 165 0.084 0.0416 0.0436 1.361 1.09 1 1.18 0.263 0.118 0.0258 1.588 1.3 1.03 1.64 0.212 0.121 0.0779 1.108 1.24 0.977 1.57 0.189 0.125 0.133 0.8765 1.21 0.944 1.54 PRS_PLINK_0.0199526231496888 FALSE 317.1 Alcoholism Both 544 4532 5 mental disorders magenta 4532, 544 1133, 112 1133, 149 1133, 149 1133, 134 0.0986 0.0461 0.0324 1.49 1.1 1.01 1.21 0.294 0.132 0.0264 1.579 1.34 1.04 1.74 0.277 0.134 0.0385 1.415 1.32 1.01 1.71 0.219 0.14 0.118 0.9284 1.24 0.946 1.64 PRS_PLINK_0.0199526231496888 FALSE 317.11 Alcoholic liver damage Both 139 869 5 mental disorders magenta 869, 139 218, 29 217, 36 217, 36 217, 38 0.139 0.0928 0.134 0.8726 1.15 0.958 1.38 0.267 0.266 0.315 0.5011 1.31 0.776 2.2 0.347 0.271 0.2 0.6994 1.41 0.832 2.41 0.355 0.275 0.196 0.7077 1.43 0.833 2.44 PRS_PLINK_0.0199526231496888 FALSE 318 Tobacco use disorder Both 2421 9429 5 mental disorders magenta 9429, 2421 2358, 583 2357, 575 2357, 607 2357, 656 0.0555 0.0235 0.0183 1.738 1.06 1.01 1.11 -0.0168 0.0664 0.8 0.09672 0.983 0.863 1.12 0.0434 0.0666 0.514 0.2888 1.04 0.917 1.19 0.127 0.0673 0.0591 1.228 1.14 0.995 1.3 PRS_PLINK_0.0199526231496888 FALSE 320 Meningitis Both 113 1048 6 neurological darkblue 1048, 113 262, 31 262, 28 262, 22 262, 32 0.0124 0.1 0.902 0.04498 1.01 0.832 1.23 -0.165 0.275 0.549 0.2603 0.848 0.495 1.45 -0.285 0.286 0.319 0.4963 0.752 0.429 1.32 0.159 0.272 0.561 0.2513 1.17 0.687 2 PRS_PLINK_0.0199526231496888 FALSE 323 Encephalitis Both 54 465 6 neurological darkblue 465, 54 117, 11 116, 14 116, 16 116, 13 0.034 0.141 0.809 0.09186 1.03 0.785 1.36 0.248 0.412 0.548 0.2616 1.28 0.571 2.87 0.329 0.404 0.416 0.381 1.39 0.629 3.07 0.198 0.443 0.654 0.1845 1.22 0.512 2.9 PRS_PLINK_0.0199526231496888 FALSE 323.8 Encephalitis, non-infectious Both 47 385 6 neurological darkblue 385, 47 97, 10 96, 15 96, 13 96, 9 -0.0709 0.151 0.64 0.1939 0.932 0.692 1.25 0.411 0.419 0.327 0.4854 1.51 0.663 3.43 0.246 0.438 0.574 0.2409 1.28 0.542 3.02 -0.155 0.489 0.752 0.1238 0.857 0.328 2.24 PRS_PLINK_0.0199526231496888 TRUE 324 Other CNS infection and poliomyelitis Both 60 639 6 neurological darkblue 639, 60 160, 15 160, 9 159, 18 160, 18 0.124 0.137 0.364 0.4393 1.13 0.866 1.48 -0.517 0.416 0.214 0.6698 0.596 0.264 1.35 0.381 0.374 0.309 0.51 1.46 0.703 3.05 0.228 0.368 0.536 0.2709 1.26 0.61 2.58 PRS_PLINK_0.0199526231496888 FALSE 325 Phlebitis and thrombophlebitis of intracranial venous sinuses Both 14 162 6 neurological darkblue 162, 14 41, 5 40, 0 40, 5 41, 4 -0.143 0.307 0.641 0.1934 0.866 0.475 1.58 -2.88 1.39 0.0382 1.418 0.0559 0.00366 0.855 -0.757 0.769 0.325 0.4882 0.469 0.104 2.12 -0.253 0.703 0.719 0.1432 0.777 0.196 3.08 PRS_PLINK_0.0199526231496888 TRUE 327 Sleep disorders Both 3569 9210 6 neurological darkblue 9210, 3569 2303, 908 2302, 933 2302, 848 2303, 879 0.0137 0.0207 0.509 0.2929 1.01 0.973 1.06 0.0557 0.0567 0.326 0.4867 1.06 0.946 1.18 -0.04 0.0582 0.491 0.3086 0.961 0.857 1.08 0.0222 0.0598 0.711 0.1483 1.02 0.909 1.15 PRS_PLINK_0.0199526231496888 FALSE 327.1 Hypersomnia Both 522 5532 6 neurological darkblue 5532, 522 1383, 152 1383, 123 1383, 124 1383, 123 -0.0436 0.0471 0.355 0.4496 0.957 0.873 1.05 -0.206 0.127 0.106 0.9756 0.814 0.634 1.04 -0.177 0.129 0.169 0.7722 0.838 0.651 1.08 -0.218 0.133 0.101 0.9942 0.804 0.62 1.04 PRS_PLINK_0.0199526231496888 FALSE 327.3 Sleep apnea Both 2208 9054 6 neurological darkblue 9054, 2208 2264, 562 2263, 571 2263, 525 2264, 549 0.0208 0.0251 0.406 0.3912 1.02 0.972 1.07 0.0624 0.069 0.365 0.4372 1.06 0.93 1.22 -0.0391 0.0707 0.581 0.2361 0.962 0.837 1.1 0.0436 0.0727 0.549 0.2607 1.04 0.906 1.2 PRS_PLINK_0.0199526231496888 FALSE 327.31 Central/nonobstroctive sleep apnea Both 124 977 6 neurological darkblue 977, 124 245, 23 244, 40 244, 27 244, 34 0.082 0.103 0.426 0.3703 1.09 0.887 1.33 0.613 0.277 0.0268 1.572 1.85 1.07 3.17 0.17 0.293 0.562 0.2505 1.19 0.667 2.11 0.425 0.296 0.151 0.8205 1.53 0.856 2.74 PRS_PLINK_0.0199526231496888 FALSE 327.32 Obstructive sleep apnea Both 1763 8671 6 neurological darkblue 8671, 1763 2168, 464 2168, 449 2167, 416 2168, 433 0.00781 0.0275 0.776 0.1099 1.01 0.955 1.06 0.0142 0.0754 0.851 0.07031 1.01 0.875 1.18 -0.0894 0.0773 0.248 0.6057 0.915 0.786 1.06 -0.00207 0.0795 0.979 0.009138 0.998 0.854 1.17 PRS_PLINK_0.0199526231496888 FALSE 327.4 Insomnia Both 1603 9035 6 neurological darkblue 9035, 1603 2259, 421 2259, 425 2258, 375 2259, 382 -0.0165 0.0283 0.56 0.2517 0.984 0.931 1.04 0.0371 0.0762 0.626 0.2034 1.04 0.894 1.21 -0.0856 0.0791 0.279 0.5543 0.918 0.786 1.07 -0.0236 0.0814 0.772 0.1124 0.977 0.833 1.15 PRS_PLINK_0.0199526231496888 FALSE 327.41 Organic or persistent insomnia Both 345 3285 6 neurological darkblue 3285, 345 822, 93 821, 90 821, 83 821, 79 -0.0712 0.0584 0.222 0.6528 0.931 0.831 1.04 -0.0115 0.156 0.941 0.02641 0.989 0.728 1.34 -0.0618 0.162 0.702 0.1535 0.94 0.685 1.29 -0.116 0.168 0.489 0.3105 0.89 0.641 1.24 PRS_PLINK_0.0199526231496888 FALSE 327.5 Parasomnia Both 141 1441 6 neurological darkblue 1441, 141 361, 42 360, 27 360, 39 360, 33 0.00289 0.0899 0.974 0.01128 1 0.841 1.2 -0.431 0.253 0.0887 1.052 0.65 0.396 1.07 -0.07 0.232 0.763 0.1174 0.932 0.591 1.47 -0.211 0.247 0.393 0.4055 0.81 0.499 1.31 PRS_PLINK_0.0199526231496888 FALSE 327.6 Circadian rhythm sleep disorder Both 84 810 6 neurological darkblue 810, 84 203, 20 202, 30 202, 16 203, 18 -0.0521 0.119 0.662 0.1795 0.949 0.752 1.2 0.392 0.309 0.204 0.6899 1.48 0.808 2.71 -0.053 0.358 0.882 0.05443 0.948 0.471 1.91 0.0395 0.372 0.915 0.03835 1.04 0.501 2.16 PRS_PLINK_0.0199526231496888 FALSE 327.7 Sleep related movement disorders Both 455 4570 6 neurological darkblue 4570, 455 1143, 108 1142, 123 1142, 100 1143, 124 0.0982 0.0509 0.0538 1.269 1.1 0.998 1.22 0.148 0.138 0.284 0.546 1.16 0.884 1.52 -0.0774 0.147 0.598 0.2236 0.926 0.694 1.23 0.195 0.144 0.175 0.7558 1.22 0.917 1.61 PRS_PLINK_0.0199526231496888 FALSE 327.71 Restless legs syndrome Both 402 4065 6 neurological darkblue 4065, 402 1017, 94 1016, 108 1016, 88 1016, 112 0.117 0.0543 0.0309 1.51 1.12 1.01 1.25 0.169 0.148 0.253 0.5974 1.18 0.886 1.58 -0.0385 0.156 0.806 0.09388 0.962 0.708 1.31 0.231 0.152 0.129 0.8911 1.26 0.935 1.7 PRS_PLINK_0.0199526231496888 FALSE 327.72 Sleep related leg cramps Both 19 199 6 neurological darkblue 199, 19 50, 7 50, 7 49, 3 50, 2 -0.391 0.246 0.112 0.9508 0.676 0.418 1.1 0.0402 0.557 0.943 0.02572 1.04 0.349 3.1 -0.917 0.689 0.183 0.7365 0.4 0.104 1.54 -1.13 0.792 0.153 0.8153 0.323 0.0683 1.52 PRS_PLINK_0.0199526231496888 TRUE 331 Other cerebral degenerations Both 144 1435 6 neurological darkblue 1435, 144 359, 38 359, 31 358, 29 359, 46 0.0399 0.0891 0.655 0.184 1.04 0.874 1.24 -0.204 0.251 0.417 0.3803 0.816 0.499 1.33 -0.295 0.26 0.257 0.5901 0.745 0.448 1.24 0.28 0.244 0.251 0.6008 1.32 0.821 2.13 PRS_PLINK_0.0199526231496888 FALSE 331.1 Hydrocephalus Both 64 721 6 neurological darkblue 721, 64 181, 15 180, 11 180, 13 180, 25 0.12 0.131 0.362 0.4418 1.13 0.871 1.46 -0.231 0.387 0.551 0.2589 0.794 0.372 1.7 -0.167 0.38 0.661 0.1801 0.846 0.402 1.78 0.577 0.354 0.104 0.985 1.78 0.889 3.57 PRS_PLINK_0.0199526231496888 FALSE 331.9 Cerebral degeneration, unspecified Both 77 717 6 neurological darkblue 717, 77 180, 22 179, 14 179, 17 179, 24 0.0358 0.12 0.765 0.1163 1.04 0.819 1.31 -0.419 0.348 0.228 0.6428 0.657 0.333 1.3 -0.248 0.343 0.47 0.3283 0.78 0.398 1.53 -0.00244 0.321 0.994 0.002638 0.998 0.532 1.87 PRS_PLINK_0.0199526231496888 FALSE 332 Parkinson's disease Both 78 702 6 neurological darkblue 702, 78 176, 31 175, 13 175, 16 176, 18 -0.114 0.118 0.336 0.4732 0.892 0.708 1.13 -0.827 0.345 0.0165 1.783 0.437 0.223 0.86 -0.654 0.326 0.0451 1.346 0.52 0.274 0.986 -0.587 0.322 0.0684 1.165 0.556 0.296 1.05 PRS_PLINK_0.0199526231496888 FALSE 333 Extrapyramidal disease and abnormal movement disorders Both 724 6789 6 neurological darkblue 6789, 724 1698, 180 1697, 188 1697, 169 1697, 187 0.0321 0.0405 0.428 0.3687 1.03 0.954 1.12 0.0663 0.11 0.547 0.2616 1.07 0.861 1.33 -0.0327 0.115 0.775 0.1105 0.968 0.773 1.21 0.127 0.115 0.27 0.5684 1.14 0.906 1.42 PRS_PLINK_0.0199526231496888 FALSE 333.1 Essential tremor Both 148 1417 6 neurological darkblue 1417, 148 355, 35 354, 33 354, 39 354, 41 0.0545 0.0909 0.549 0.2607 1.06 0.884 1.26 -0.0737 0.251 0.769 0.1142 0.929 0.568 1.52 0.176 0.244 0.472 0.3264 1.19 0.739 1.92 0.229 0.248 0.355 0.4497 1.26 0.774 2.04 PRS_PLINK_0.0199526231496888 FALSE 333.2 Myoclonus Both 37 394 6 neurological darkblue 394, 37 99, 7 98, 10 98, 13 99, 7 0.108 0.178 0.542 0.2662 1.11 0.787 1.58 0.439 0.477 0.357 0.4475 1.55 0.61 3.95 0.772 0.466 0.0971 1.013 2.17 0.869 5.39 0.308 0.525 0.558 0.2537 1.36 0.486 3.8 PRS_PLINK_0.0199526231496888 TRUE 333.4 Torsion dystonia Both 100 908 6 neurological darkblue 908, 100 227, 30 227, 23 227, 26 227, 21 -0.105 0.108 0.33 0.4815 0.9 0.729 1.11 -0.254 0.289 0.38 0.4205 0.776 0.44 1.37 -0.0869 0.284 0.759 0.1196 0.917 0.526 1.6 -0.249 0.306 0.416 0.3813 0.779 0.428 1.42 PRS_PLINK_0.0199526231496888 FALSE 333.8 Other degenerative diseases of the basal ganglia Both 25 159 6 neurological darkblue 159, 25 40, 7 40, 6 39, 9 40, 3 -0.24 0.218 0.271 0.5666 0.787 0.513 1.21 -0.513 0.629 0.415 0.3818 0.599 0.174 2.06 -0.0237 0.582 0.967 0.01438 0.977 0.312 3.05 -1.2 0.776 0.122 0.915 0.301 0.0658 1.38 PRS_PLINK_0.0199526231496888 TRUE 334 Degenerative disease of the spinal cord Both 251 2507 6 neurological darkblue 2507, 251 627, 53 627, 57 626, 70 627, 71 0.135 0.0688 0.0493 1.307 1.14 1 1.31 0.0803 0.199 0.686 0.1637 1.08 0.734 1.6 0.276 0.192 0.151 0.8212 1.32 0.904 1.92 0.261 0.2 0.193 0.7139 1.3 0.876 1.92 PRS_PLINK_0.0199526231496888 FALSE 334.1 Spinocerebellar disease Both 16 178 6 neurological darkblue 178, 16 45, 4 44, 5 44, 5 45, 2 -0.156 0.256 0.541 0.2667 0.855 0.518 1.41 0.0787 0.664 0.906 0.04299 1.08 0.294 3.98 0.139 0.672 0.836 0.07787 1.15 0.308 4.29 -0.657 0.775 0.397 0.4017 0.519 0.114 2.37 PRS_PLINK_0.0199526231496888 TRUE 334.2 Anterior horn cell disease Both 31 238 6 neurological darkblue 238, 31 60, 5 59, 2 59, 9 60, 15 0.583 0.212 0.00589 2.23 1.79 1.18 2.71 -0.668 0.795 0.401 0.3969 0.513 0.108 2.44 0.671 0.552 0.224 0.6495 1.96 0.663 5.77 0.967 0.52 0.0631 1.2 2.63 0.949 7.29 PRS_PLINK_0.0199526231496888 TRUE 334.21 Amyotrophic Lateral Sclerosis Both 17 135 6 neurological darkblue 135, 17 34, 3 34, 1 33, 6 34, 7 0.786 0.292 0.00699 2.155 2.2 1.24 3.89 -0.353 0.951 0.71 0.1484 0.702 0.109 4.53 0.743 0.69 0.281 0.5506 2.1 0.544 8.13 0.762 0.711 0.284 0.5466 2.14 0.532 8.63 PRS_PLINK_0.0199526231496888 TRUE 335 Multiple sclerosis Both 126 1149 6 neurological darkblue 1149, 126 288, 33 287, 31 287, 27 287, 35 0.0872 0.0922 0.344 0.4634 1.09 0.911 1.31 -0.0854 0.261 0.744 0.1285 0.918 0.55 1.53 -0.154 0.272 0.57 0.2438 0.857 0.503 1.46 -0.0266 0.266 0.92 0.03606 0.974 0.579 1.64 PRS_PLINK_0.0199526231496888 FALSE 337 Disorders of the autonomic nervous system Both 212 1898 6 neurological darkblue 1898, 212 475, 50 474, 44 474, 59 475, 59 0.0701 0.0738 0.342 0.4662 1.07 0.928 1.24 -0.14 0.217 0.52 0.2843 0.87 0.568 1.33 0.157 0.206 0.447 0.3499 1.17 0.781 1.75 0.0769 0.21 0.715 0.1459 1.08 0.715 1.63 PRS_PLINK_0.0199526231496888 FALSE 337.1 Peripheral autonomic neuropathy Both 72 655 6 neurological darkblue 655, 72 164, 16 164, 16 163, 21 164, 19 0.163 0.129 0.207 0.6833 1.18 0.914 1.52 0.00266 0.369 0.994 0.002508 1 0.487 2.07 0.314 0.354 0.376 0.4249 1.37 0.683 2.74 0.159 0.357 0.657 0.1822 1.17 0.582 2.36 PRS_PLINK_0.0199526231496888 FALSE 338 Pain Both 5720 7111 6 neurological darkblue 7111, 5720 1778, 1440 1778, 1357 1777, 1495 1778, 1427 0.0157 0.0184 0.395 0.4039 1.02 0.98 1.05 -0.0549 0.0514 0.285 0.5452 0.947 0.856 1.05 0.0378 0.0514 0.463 0.3348 1.04 0.939 1.15 -0.00768 0.0533 0.885 0.05284 0.992 0.894 1.1 PRS_PLINK_0.0199526231496888 FALSE 338.1 Acute pain Both 4412 7071 6 neurological darkblue 7071, 4412 1768, 1089 1768, 1033 1767, 1171 1768, 1118 0.0267 0.0199 0.181 0.7432 1.03 0.988 1.07 -0.0552 0.0558 0.323 0.4909 0.946 0.848 1.06 0.0619 0.0555 0.265 0.576 1.06 0.954 1.19 0.00564 0.0575 0.922 0.03532 1.01 0.898 1.13 PRS_PLINK_0.0199526231496888 FALSE 338.2 Chronic pain Both 2996 7086 6 neurological darkblue 7086, 2996 1772, 796 1771, 706 1771, 771 1772, 722 -0.011 0.0227 0.628 0.2021 0.989 0.946 1.03 -0.117 0.0628 0.0631 1.2 0.89 0.787 1.01 -0.0246 0.0625 0.694 0.1586 0.976 0.863 1.1 -0.0698 0.0652 0.284 0.5463 0.933 0.821 1.06 PRS_PLINK_0.0199526231496888 FALSE 339 Other headache syndromes Both 2928 8967 6 neurological darkblue 8967, 2928 2242, 728 2242, 723 2241, 730 2242, 746 0.00582 0.0225 0.795 0.09941 1.01 0.963 1.05 -0.036 0.0622 0.563 0.2496 0.965 0.854 1.09 -0.0119 0.0628 0.85 0.07068 0.988 0.874 1.12 -0.0164 0.0647 0.801 0.09663 0.984 0.867 1.12 PRS_PLINK_0.0199526231496888 FALSE 340 Migraine Both 2324 8300 6 neurological darkblue 8300, 2324 2075, 561 2075, 553 2075, 602 2075, 607 0.0192 0.0248 0.44 0.3563 1.02 0.971 1.07 -0.0269 0.0693 0.698 0.1564 0.973 0.85 1.12 0.0531 0.0694 0.444 0.3526 1.05 0.92 1.21 0.0245 0.0717 0.733 0.1349 1.02 0.89 1.18 PRS_PLINK_0.0199526231496888 FALSE 340.1 Migrain with aura Both 1221 6970 6 neurological darkblue 6970, 1221 1743, 300 1742, 310 1742, 304 1743, 307 0.00649 0.0324 0.841 0.07505 1.01 0.945 1.07 0.0211 0.0887 0.812 0.09043 1.02 0.858 1.22 0.0176 0.0906 0.846 0.07244 1.02 0.852 1.22 0.00869 0.0933 0.926 0.03349 1.01 0.84 1.21 PRS_PLINK_0.0199526231496888 FALSE 341 Other demyelinating diseases of central nervous system Both 44 382 6 neurological darkblue 382, 44 96, 10 95, 11 95, 10 96, 13 0.102 0.15 0.498 0.3032 1.11 0.825 1.49 0.035 0.446 0.937 0.02804 1.04 0.432 2.48 0.135 0.45 0.763 0.1172 1.14 0.474 2.76 0.132 0.443 0.765 0.1163 1.14 0.479 2.72 PRS_PLINK_0.0199526231496888 TRUE 342 Hemiplegia Both 113 1089 6 neurological darkblue 1089, 113 273, 26 272, 23 272, 36 272, 28 -0.01 0.101 0.921 0.0358 0.99 0.813 1.21 -0.0422 0.295 0.886 0.05242 0.959 0.538 1.71 0.334 0.276 0.226 0.645 1.4 0.813 2.4 0.0566 0.298 0.849 0.07092 1.06 0.59 1.9 PRS_PLINK_0.0199526231496888 FALSE 343 Infantile cerebral palsy Both 32 327 6 neurological darkblue 327, 32 82, 10 82, 4 81, 7 82, 11 0.139 0.174 0.422 0.3742 1.15 0.818 1.62 -0.977 0.573 0.088 1.056 0.376 0.123 1.16 -0.201 0.496 0.685 0.1642 0.818 0.309 2.16 0.428 0.489 0.381 0.4192 1.53 0.589 4 PRS_PLINK_0.0199526231496888 TRUE 344 Other paralytic syndromes Both 194 1653 6 neurological darkblue 1653, 194 414, 43 413, 50 413, 49 413, 52 0.0519 0.0785 0.508 0.294 1.05 0.903 1.23 0.152 0.218 0.486 0.3135 1.16 0.759 1.79 0.0841 0.222 0.705 0.1521 1.09 0.704 1.68 0.163 0.224 0.466 0.3316 1.18 0.759 1.83 PRS_PLINK_0.0199526231496888 FALSE 345 Epilepsy, recurrent seizures, convulsions Both 800 7274 6 neurological darkblue 7274, 800 1819, 183 1818, 181 1818, 224 1819, 211 0.0721 0.0383 0.0597 1.224 1.07 0.997 1.16 -0.00826 0.11 0.94 0.02681 0.992 0.799 1.23 0.234 0.107 0.0283 1.547 1.26 1.03 1.56 0.178 0.111 0.109 0.9632 1.19 0.961 1.48 PRS_PLINK_0.0199526231496888 FALSE 345.1 Epilepsy Both 257 2159 6 neurological darkblue 2159, 257 540, 68 540, 61 539, 58 540, 70 0.0168 0.0687 0.807 0.09314 1.02 0.889 1.16 -0.0945 0.185 0.61 0.2144 0.91 0.633 1.31 -0.108 0.19 0.57 0.2443 0.898 0.618 1.3 0.0587 0.19 0.757 0.1207 1.06 0.731 1.54 PRS_PLINK_0.0199526231496888 FALSE 345.11 Generalized convulsive epilepsy Both 83 732 6 neurological darkblue 732, 83 183, 19 183, 16 183, 22 183, 26 0.213 0.12 0.0754 1.123 1.24 0.978 1.57 -0.147 0.344 0.669 0.1743 0.863 0.44 1.69 0.233 0.335 0.486 0.3129 1.26 0.654 2.44 0.361 0.335 0.281 0.5507 1.44 0.744 2.77 PRS_PLINK_0.0199526231496888 FALSE 345.12 Partial epilepsy Both 178 1517 6 neurological darkblue 1517, 178 380, 53 379, 34 379, 44 379, 47 -0.0483 0.0822 0.557 0.254 0.953 0.811 1.12 -0.407 0.229 0.0752 1.124 0.665 0.425 1.04 -0.136 0.217 0.53 0.2755 0.872 0.57 1.34 -0.126 0.22 0.568 0.2457 0.882 0.573 1.36 PRS_PLINK_0.0199526231496888 FALSE 345.3 Convulsions Both 741 6885 6 neurological darkblue 6885, 741 1722, 176 1721, 161 1721, 209 1721, 194 0.0615 0.0397 0.122 0.9147 1.06 0.984 1.15 -0.0873 0.114 0.445 0.352 0.916 0.733 1.15 0.202 0.109 0.0649 1.188 1.22 0.988 1.52 0.131 0.114 0.252 0.5979 1.14 0.911 1.43 PRS_PLINK_0.0199526231496888 FALSE 346 Abnormal findings on study of brain and/or nervous system Both 48 433 6 neurological darkblue 433, 48 109, 15 108, 7 108, 13 108, 12 -0.111 0.154 0.471 0.3267 0.895 0.661 1.21 -0.79 0.449 0.0783 1.106 0.454 0.188 1.09 -0.094 0.393 0.811 0.09101 0.91 0.421 1.97 -0.386 0.412 0.348 0.4579 0.68 0.303 1.52 PRS_PLINK_0.0199526231496888 TRUE 346.1 Nonspecific abnormal findings on radiological and other examination of skull and head Both 373 3468 6 neurological darkblue 3468, 373 867, 91 867, 79 867, 98 867, 105 0.0864 0.0572 0.131 0.882 1.09 0.975 1.22 -0.13 0.161 0.419 0.3774 0.878 0.641 1.2 0.0671 0.155 0.665 0.1773 1.07 0.789 1.45 0.135 0.157 0.389 0.4105 1.14 0.842 1.56 PRS_PLINK_0.0199526231496888 FALSE 346.2 Nonspecific abnormal results of function study of brain and central nervous system Both 31 285 6 neurological darkblue 285, 31 72, 10 71, 3 71, 8 71, 10 0.0842 0.206 0.684 0.1652 1.09 0.726 1.63 -1.28 0.641 0.0462 1.335 0.279 0.0793 0.979 -0.244 0.491 0.619 0.2086 0.783 0.299 2.05 0.0209 0.489 0.966 0.01502 1.02 0.391 2.66 PRS_PLINK_0.0199526231496888 TRUE 346.3 Nonspecific abnormal findings in cerebrospinal fluid Both 32 308 6 neurological darkblue 308, 32 77, 8 77, 6 77, 11 77, 7 0.113 0.186 0.542 0.266 1.12 0.778 1.61 -0.0871 0.541 0.872 0.05939 0.917 0.317 2.65 0.287 0.481 0.551 0.2592 1.33 0.519 3.42 -0.0415 0.542 0.939 0.02739 0.959 0.332 2.77 PRS_PLINK_0.0199526231496888 TRUE 347 Cataplexy and narcolepsy Both 33 346 6 neurological darkblue 346, 33 87, 10 86, 5 86, 8 87, 10 0.051 0.182 0.779 0.1086 1.05 0.737 1.5 -0.855 0.533 0.109 0.9629 0.425 0.15 1.21 -0.345 0.47 0.463 0.3349 0.708 0.282 1.78 -0.124 0.459 0.787 0.1041 0.883 0.359 2.17 PRS_PLINK_0.0199526231496888 TRUE 348 Other conditions of brain Both 478 4727 6 neurological darkblue 4727, 478 1182, 104 1182, 117 1181, 132 1182, 125 0.0949 0.0494 0.0549 1.26 1.1 0.998 1.21 0.109 0.141 0.439 0.3572 1.11 0.846 1.47 0.228 0.139 0.1 0.9995 1.26 0.957 1.65 0.193 0.144 0.18 0.7443 1.21 0.915 1.61 PRS_PLINK_0.0199526231496888 FALSE 348.2 Cerebral edema and compression of brain Both 230 2585 6 neurological darkblue 2585, 230 647, 61 646, 53 646, 59 646, 57 0.018 0.0705 0.799 0.09752 1.02 0.887 1.17 -0.123 0.193 0.526 0.2786 0.885 0.605 1.29 -0.0453 0.19 0.812 0.09057 0.956 0.659 1.39 -0.0445 0.197 0.821 0.08547 0.956 0.65 1.41 PRS_PLINK_0.0199526231496888 FALSE 348.4 Cerebral cysts Both 67 717 6 neurological darkblue 717, 67 180, 17 179, 11 179, 21 179, 18 0.0672 0.133 0.614 0.2119 1.07 0.824 1.39 -0.548 0.389 0.159 0.7988 0.578 0.27 1.24 0.138 0.339 0.683 0.1655 1.15 0.591 2.23 -0.092 0.37 0.804 0.09501 0.912 0.442 1.88 PRS_PLINK_0.0199526231496888 FALSE 348.7 Coma Both 59 551 6 neurological darkblue 551, 59 138, 17 138, 9 137, 16 138, 17 0.037 0.141 0.793 0.1006 1.04 0.787 1.37 -0.656 0.411 0.11 0.9569 0.519 0.232 1.16 -0.00228 0.36 0.995 0.002199 0.998 0.493 2.02 0.18 0.375 0.632 0.1992 1.2 0.574 2.5 PRS_PLINK_0.0199526231496888 FALSE 348.8 Encephalopathy, not elsewhere classified Both 214 1888 6 neurological darkblue 1888, 214 472, 41 472, 56 472, 58 472, 59 0.111 0.073 0.129 0.8908 1.12 0.968 1.29 0.325 0.215 0.13 0.8877 1.38 0.909 2.11 0.342 0.214 0.11 0.9578 1.41 0.925 2.14 0.379 0.218 0.0818 1.087 1.46 0.953 2.24 PRS_PLINK_0.0199526231496888 FALSE 348.9 Other conditions of brain, NOS Both 577 6002 6 neurological darkblue 6002, 577 1501, 158 1500, 120 1500, 141 1501, 158 0.024 0.0452 0.595 0.2254 1.02 0.938 1.12 -0.268 0.126 0.0341 1.468 0.765 0.597 0.98 -0.132 0.124 0.286 0.5433 0.877 0.688 1.12 -0.00704 0.123 0.954 0.02024 0.993 0.78 1.26 PRS_PLINK_0.0199526231496888 FALSE 349 Other and unspecified disorders of the nervous system Both 262 2498 6 neurological darkblue 2498, 262 625, 72 624, 53 624, 61 625, 76 0.0473 0.0662 0.476 0.3227 1.05 0.921 1.19 -0.295 0.188 0.116 0.935 0.745 0.516 1.08 -0.168 0.184 0.361 0.4425 0.845 0.59 1.21 0.0116 0.179 0.948 0.02305 1.01 0.713 1.44 PRS_PLINK_0.0199526231496888 FALSE 350 Abnormal movement Both 1662 10736 6 neurological darkblue 10736, 1662 2683, 434 2684, 397 2684, 406 2684, 425 0.00891 0.0273 0.744 0.1285 1.01 0.956 1.06 -0.0583 0.0756 0.44 0.3562 0.943 0.813 1.09 -0.0312 0.0761 0.682 0.1665 0.969 0.835 1.13 0.0605 0.0778 0.437 0.3598 1.06 0.912 1.24 PRS_PLINK_0.0199526231496888 FALSE 350.1 Abnormal involuntary movements Both 879 7829 6 neurological darkblue 7829, 879 1958, 251 1957, 198 1957, 206 1957, 224 -0.0467 0.0365 0.201 0.6977 0.954 0.888 1.03 -0.226 0.1 0.0245 1.61 0.798 0.655 0.971 -0.193 0.101 0.0557 1.254 0.825 0.677 1 -0.118 0.101 0.242 0.6157 0.888 0.729 1.08 PRS_PLINK_0.0199526231496888 FALSE 350.2 Abnormality of gait Both 853 7330 6 neurological darkblue 7330, 853 1833, 202 1832, 190 1832, 216 1833, 245 0.0882 0.0373 0.018 1.744 1.09 1.02 1.17 -0.0068 0.107 0.949 0.02256 0.993 0.805 1.23 0.121 0.105 0.249 0.6042 1.13 0.919 1.39 0.28 0.106 0.00816 2.089 1.32 1.08 1.63 PRS_PLINK_0.0199526231496888 FALSE 350.3 Lack of coordination Both 275 2672 6 neurological darkblue 2672, 275 668, 80 668, 72 668, 63 668, 60 -0.172 0.065 0.00805 2.094 0.842 0.741 0.956 -0.133 0.171 0.437 0.3591 0.876 0.627 1.22 -0.226 0.178 0.206 0.686 0.798 0.562 1.13 -0.274 0.187 0.143 0.8449 0.76 0.526 1.1 PRS_PLINK_0.0199526231496888 FALSE 350.5 Abnormal reflex Both 46 473 6 neurological darkblue 473, 46 119, 15 118, 10 118, 9 118, 12 -0.0698 0.156 0.654 0.1843 0.933 0.687 1.27 -0.377 0.405 0.353 0.4525 0.686 0.31 1.52 -0.413 0.438 0.346 0.4605 0.662 0.28 1.56 -0.0765 0.405 0.85 0.07058 0.926 0.419 2.05 PRS_PLINK_0.0199526231496888 TRUE 350.6 Disturbances of sensation of smell and taste Both 137 1271 6 neurological darkblue 1271, 137 318, 36 318, 32 317, 32 318, 37 -0.0959 0.0894 0.284 0.5472 0.909 0.762 1.08 -0.134 0.252 0.595 0.2252 0.875 0.533 1.43 -0.13 0.255 0.609 0.2155 0.878 0.533 1.45 0.0237 0.252 0.925 0.03377 1.02 0.624 1.68 PRS_PLINK_0.0199526231496888 FALSE 351 Other peripheral nerve disorders Both 1791 9677 6 neurological darkblue 9677, 1791 2420, 492 2419, 439 2419, 447 2419, 412 -0.0422 0.0267 0.114 0.9447 0.959 0.91 1.01 -0.101 0.0727 0.163 0.7872 0.904 0.784 1.04 -0.0936 0.0734 0.203 0.6934 0.911 0.789 1.05 -0.108 0.077 0.162 0.7914 0.898 0.772 1.04 PRS_PLINK_0.0199526231496888 FALSE 352 Disorders of other cranial nerves Both 398 4523 6 neurological darkblue 4523, 398 1131, 104 1131, 104 1130, 88 1131, 102 0.0103 0.0537 0.848 0.07146 1.01 0.909 1.12 -0.00293 0.144 0.984 0.007111 0.997 0.752 1.32 -0.181 0.152 0.236 0.6275 0.835 0.619 1.13 -0.00269 0.151 0.986 0.006212 0.997 0.741 1.34 PRS_PLINK_0.0199526231496888 FALSE 352.1 Trigeminal nerve disorders [CN5] Both 141 1525 6 neurological darkblue 1525, 141 382, 35 381, 34 381, 32 381, 40 0.0519 0.0899 0.564 0.2489 1.05 0.883 1.26 -0.0206 0.247 0.934 0.02983 0.98 0.604 1.59 -0.108 0.257 0.674 0.1716 0.898 0.543 1.48 0.0742 0.25 0.767 0.1154 1.08 0.66 1.76 PRS_PLINK_0.0199526231496888 FALSE 352.2 Facial nerve disorders [CN7] Both 183 2044 6 neurological darkblue 2044, 183 511, 53 511, 42 511, 43 511, 45 -0.0216 0.079 0.785 0.1053 0.979 0.838 1.14 -0.229 0.213 0.282 0.5492 0.795 0.524 1.21 -0.192 0.214 0.37 0.4316 0.825 0.542 1.26 -0.0875 0.218 0.688 0.1622 0.916 0.597 1.41 PRS_PLINK_0.0199526231496888 FALSE 353 Nerve root and plexus disorders Both 1023 9096 6 neurological darkblue 9096, 1023 2274, 253 2274, 295 2274, 236 2274, 239 -0.0387 0.034 0.256 0.5923 0.962 0.9 1.03 0.157 0.0912 0.0849 1.071 1.17 0.979 1.4 -0.0581 0.0971 0.55 0.2598 0.944 0.78 1.14 -0.0179 0.1 0.858 0.06673 0.982 0.807 1.19 PRS_PLINK_0.0199526231496888 FALSE 353.1 Nerve plexus lesions Both 118 1196 6 neurological darkblue 1196, 118 299, 32 299, 37 299, 30 299, 19 -0.137 0.0993 0.168 0.7746 0.872 0.718 1.06 0.121 0.251 0.629 0.2013 1.13 0.69 1.85 -0.0193 0.265 0.942 0.02599 0.981 0.583 1.65 -0.421 0.304 0.167 0.7768 0.657 0.362 1.19 PRS_PLINK_0.0199526231496888 FALSE 353.2 Nerve root lesions Both 30 301 6 neurological darkblue 301, 30 76, 8 75, 6 75, 5 75, 11 0.201 0.195 0.303 0.5185 1.22 0.834 1.79 -0.336 0.524 0.521 0.283 0.714 0.256 2 -0.26 0.535 0.628 0.2023 0.771 0.27 2.2 0.322 0.491 0.512 0.2907 1.38 0.527 3.61 PRS_PLINK_0.0199526231496888 TRUE 355 Complex regional/central pain syndrome Both 155 1632 6 neurological darkblue 1632, 155 408, 37 408, 50 408, 34 408, 33 -0.0716 0.0857 0.403 0.3943 0.931 0.787 1.1 0.326 0.227 0.151 0.8211 1.39 0.888 2.16 -0.134 0.248 0.588 0.2308 0.874 0.538 1.42 -0.178 0.26 0.493 0.3072 0.837 0.503 1.39 PRS_PLINK_0.0199526231496888 FALSE 355.1 Chronic pain syndrome Both 259 2519 6 neurological darkblue 2519, 259 630, 54 630, 70 629, 63 630, 72 0.151 0.0663 0.0231 1.637 1.16 1.02 1.32 0.253 0.189 0.179 0.7462 1.29 0.89 1.86 0.157 0.195 0.42 0.3769 1.17 0.799 1.71 0.292 0.194 0.131 0.8813 1.34 0.916 1.96 PRS_PLINK_0.0199526231496888 FALSE 356 Hereditary and idiopathic peripheral neuropathy Both 448 4646 6 neurological darkblue 4646, 448 1162, 112 1161, 111 1161, 113 1162, 112 0.0278 0.0513 0.588 0.2303 1.03 0.93 1.14 0.0123 0.141 0.93 0.03147 1.01 0.769 1.33 0.00253 0.141 0.986 0.006255 1 0.76 1.32 -0.00617 0.146 0.966 0.01494 0.994 0.747 1.32 PRS_PLINK_0.0199526231496888 FALSE 357 Inflammatory and toxic neuropathy Both 738 6991 6 neurological darkblue 6991, 738 1748, 209 1748, 171 1747, 182 1748, 175 -0.031 0.0399 0.437 0.3593 0.97 0.897 1.05 -0.181 0.109 0.0968 1.014 0.834 0.674 1.03 -0.15 0.109 0.166 0.7788 0.86 0.695 1.06 -0.165 0.113 0.144 0.8426 0.848 0.679 1.06 PRS_PLINK_0.0199526231496888 FALSE 358 Myoneural disorders Both 295 2950 6 neurological darkblue 2950, 295 738, 90 737, 65 737, 63 738, 77 -0.0257 0.0624 0.681 0.1671 0.975 0.862 1.1 -0.347 0.172 0.0433 1.363 0.707 0.505 0.99 -0.349 0.173 0.0437 1.36 0.706 0.503 0.99 -0.173 0.169 0.306 0.5145 0.841 0.603 1.17 PRS_PLINK_0.0199526231496888 FALSE 358.1 Myasthenia gravis Both 35 262 6 neurological darkblue 262, 35 66, 12 65, 7 65, 5 66, 11 -0.0818 0.185 0.657 0.1821 0.921 0.642 1.32 -0.479 0.498 0.336 0.4735 0.62 0.234 1.64 -0.9 0.538 0.0945 1.025 0.407 0.142 1.17 -0.332 0.46 0.47 0.3282 0.717 0.291 1.77 PRS_PLINK_0.0199526231496888 TRUE 359 Muscular dystrophies and other myopathies Both 332 3005 6 neurological darkblue 3005, 332 752, 91 751, 79 751, 81 751, 81 -0.028 0.0613 0.648 0.1883 0.972 0.862 1.1 -0.154 0.161 0.34 0.4692 0.857 0.625 1.18 -0.129 0.162 0.426 0.3702 0.879 0.64 1.21 -0.177 0.168 0.293 0.533 0.838 0.603 1.16 PRS_PLINK_0.0199526231496888 FALSE 359.1 Muscular dystrophies Both 22 158 6 neurological darkblue 158, 22 40, 8 39, 4 39, 3 40, 7 -0.175 0.224 0.436 0.3604 0.84 0.541 1.3 -0.53 0.663 0.424 0.3726 0.589 0.161 2.16 -1.34 0.747 0.0733 1.135 0.262 0.0606 1.13 -0.339 0.638 0.595 0.2252 0.713 0.204 2.49 PRS_PLINK_0.0199526231496888 TRUE 359.2 Myopathy Both 316 2906 6 neurological darkblue 2906, 316 727, 85 726, 77 726, 78 727, 76 -0.0243 0.0631 0.7 0.1549 0.976 0.863 1.1 -0.112 0.165 0.499 0.3022 0.894 0.647 1.24 -0.0898 0.166 0.589 0.2302 0.914 0.66 1.27 -0.183 0.173 0.292 0.5348 0.833 0.593 1.17 PRS_PLINK_0.0199526231496888 FALSE 360 Disorders of the globe Both 27 285 7 sense organs darkseagreen4 285, 27 72, 2 71, 9 71, 8 71, 8 0.358 0.211 0.0901 1.045 1.43 0.945 2.16 1.2 0.689 0.083 1.081 3.3 0.856 12.8 1.27 0.671 0.0587 1.231 3.55 0.954 13.2 1.25 0.682 0.0677 1.169 3.48 0.913 13.2 PRS_PLINK_0.0199526231496888 TRUE 360.2 Progressive myopia Both 16 155 7 sense organs darkseagreen4 155, 16 39, 1 39, 4 38, 7 39, 4 0.256 0.285 0.369 0.4328 1.29 0.739 2.26 1.53 0.968 0.114 0.9429 4.62 0.693 30.8 1.36 0.851 0.11 0.958 3.89 0.735 20.6 1.49 1.04 0.152 0.8179 4.42 0.578 33.7 PRS_PLINK_0.0199526231496888 TRUE 361 Retinal detachments and defects Both 162 1498 7 sense organs darkseagreen4 1498, 162 375, 43 374, 45 374, 40 375, 34 -0.0947 0.0849 0.265 0.577 0.91 0.77 1.07 0.0395 0.224 0.86 0.06549 1.04 0.67 1.61 -0.0706 0.232 0.761 0.1184 0.932 0.591 1.47 -0.083 0.249 0.739 0.1313 0.92 0.565 1.5 PRS_PLINK_0.0199526231496888 FALSE 361.1 Retinal detachment with retinal defect Both 72 631 7 sense organs darkseagreen4 631, 72 158, 18 158, 22 157, 15 158, 17 -0.0862 0.131 0.509 0.2932 0.917 0.71 1.19 0.141 0.33 0.67 0.1742 1.15 0.603 2.2 -0.168 0.359 0.639 0.1942 0.845 0.418 1.71 0.0201 0.364 0.956 0.01956 1.02 0.5 2.08 PRS_PLINK_0.0199526231496888 FALSE 362 Other retinal disorders Both 622 5139 7 sense organs darkseagreen4 5139, 622 1285, 146 1285, 158 1284, 165 1285, 153 0.0404 0.0444 0.363 0.4403 1.04 0.954 1.14 0.0986 0.124 0.425 0.3712 1.1 0.866 1.41 0.14 0.125 0.263 0.5797 1.15 0.9 1.47 0.139 0.13 0.288 0.5413 1.15 0.89 1.48 PRS_PLINK_0.0199526231496888 FALSE 362.2 Degeneration of macula and posterior pole of retina Both 329 3062 7 sense organs darkseagreen4 3062, 329 766, 81 765, 86 765, 85 766, 77 -0.013 0.0604 0.83 0.08088 0.987 0.877 1.11 0.105 0.164 0.522 0.2821 1.11 0.805 1.53 0.0561 0.168 0.739 0.1315 1.06 0.761 1.47 -0.0245 0.177 0.89 0.05059 0.976 0.69 1.38 PRS_PLINK_0.0199526231496888 FALSE 362.21 Macular degeneration, dry Both 63 542 7 sense organs darkseagreen4 542, 63 136, 20 135, 14 135, 16 136, 13 -0.0912 0.139 0.512 0.2909 0.913 0.695 1.2 -0.297 0.367 0.419 0.378 0.743 0.362 1.53 -0.262 0.361 0.467 0.3308 0.769 0.379 1.56 -0.248 0.399 0.535 0.272 0.781 0.357 1.71 PRS_PLINK_0.0199526231496888 FALSE 362.22 Macular degeneration, wet Both 22 166 7 sense organs darkseagreen4 166, 22 42, 6 41, 7 41, 7 42, 2 -0.183 0.253 0.469 0.3285 0.833 0.508 1.37 0.0503 0.684 0.941 0.02622 1.05 0.275 4.02 0.2 0.676 0.767 0.115 1.22 0.325 4.6 -0.87 0.839 0.3 0.5231 0.419 0.0808 2.17 PRS_PLINK_0.0199526231496888 TRUE 362.23 Cystoid macular degeneration of retina Both 65 723 7 sense organs darkseagreen4 723, 65 181, 12 181, 18 180, 19 181, 16 0.115 0.132 0.384 0.4162 1.12 0.866 1.45 0.378 0.371 0.309 0.5106 1.46 0.705 3.02 0.474 0.375 0.207 0.6844 1.61 0.77 3.35 0.428 0.398 0.282 0.5495 1.53 0.703 3.35 PRS_PLINK_0.0199526231496888 FALSE 362.26 Macular puckering of retina Both 129 1627 7 sense organs darkseagreen4 1627, 129 407, 30 407, 32 406, 29 407, 38 0.0266 0.0922 0.773 0.1119 1.03 0.857 1.23 0.0689 0.259 0.79 0.1025 1.07 0.645 1.78 -0.0577 0.27 0.83 0.08067 0.944 0.556 1.6 0.129 0.265 0.628 0.2022 1.14 0.676 1.91 PRS_PLINK_0.0199526231496888 FALSE 362.27 Drusen (degenerative) of retina Both 81 816 7 sense organs darkseagreen4 816, 81 204, 12 204, 26 204, 22 204, 21 0.158 0.125 0.207 0.6848 1.17 0.917 1.5 0.723 0.352 0.0399 1.399 2.06 1.03 4.1 0.694 0.364 0.0566 1.247 2 0.981 4.09 0.591 0.383 0.123 0.9113 1.81 0.853 3.82 PRS_PLINK_0.0199526231496888 FALSE 362.29 Macular degeneration (senile) of retina NOS Both 283 2684 7 sense organs darkseagreen4 2684, 283 671, 68 671, 72 671, 75 671, 68 0.0254 0.065 0.697 0.157 1.03 0.903 1.17 0.112 0.178 0.529 0.2765 1.12 0.789 1.59 0.111 0.181 0.541 0.2667 1.12 0.783 1.59 0.0392 0.191 0.837 0.0771 1.04 0.716 1.51 PRS_PLINK_0.0199526231496888 FALSE 362.3 Other nondiabetic retinopathy Both 146 1792 7 sense organs darkseagreen4 1792, 146 448, 42 448, 35 448, 35 448, 34 -0.0139 0.0898 0.877 0.05702 0.986 0.827 1.18 -0.129 0.237 0.586 0.232 0.879 0.553 1.4 -0.12 0.24 0.618 0.2089 0.887 0.554 1.42 -0.0802 0.249 0.747 0.1268 0.923 0.567 1.5 PRS_PLINK_0.0199526231496888 FALSE 362.31 Separation of retinal layers Both 78 866 7 sense organs darkseagreen4 866, 78 217, 29 216, 21 216, 14 217, 14 -0.326 0.122 0.00755 2.122 0.722 0.568 0.917 -0.295 0.298 0.323 0.4902 0.745 0.415 1.34 -0.719 0.337 0.0328 1.484 0.487 0.252 0.943 -0.58 0.339 0.0868 1.062 0.56 0.288 1.09 PRS_PLINK_0.0199526231496888 FALSE 362.4 Retinal vascular changes and abnomalities Both 127 1152 7 sense organs darkseagreen4 1152, 127 288, 29 288, 24 288, 40 288, 34 0.12 0.0969 0.214 0.6696 1.13 0.933 1.36 -0.144 0.283 0.612 0.2132 0.866 0.497 1.51 0.311 0.259 0.23 0.6391 1.36 0.822 2.27 0.129 0.277 0.641 0.1934 1.14 0.662 1.96 PRS_PLINK_0.0199526231496888 FALSE 362.6 Peripheral retinal degenerations Both 91 883 7 sense organs darkseagreen4 883, 91 221, 15 221, 23 220, 27 221, 26 0.12 0.113 0.291 0.5361 1.13 0.902 1.41 0.404 0.335 0.228 0.6422 1.5 0.776 2.89 0.58 0.337 0.0849 1.071 1.79 0.923 3.45 0.615 0.37 0.096 1.018 1.85 0.897 3.82 PRS_PLINK_0.0199526231496888 FALSE 362.7 Hereditary retinal dystrophies Both 46 463 7 sense organs darkseagreen4 463, 46 116, 10 116, 10 115, 17 116, 9 -0.132 0.163 0.419 0.378 0.876 0.637 1.21 0.12 0.446 0.787 0.1039 1.13 0.471 2.7 0.584 0.427 0.171 0.7659 1.79 0.777 4.14 -0.199 0.478 0.677 0.1695 0.819 0.321 2.09 PRS_PLINK_0.0199526231496888 TRUE 362.8 Retinal hemorrhage/ischemia Both 41 539 7 sense organs darkseagreen4 539, 41 135, 8 135, 14 134, 8 135, 11 0.151 0.162 0.35 0.4554 1.16 0.847 1.6 0.538 0.434 0.215 0.6681 1.71 0.732 4 0.15 0.491 0.76 0.119 1.16 0.444 3.04 0.33 0.455 0.468 0.3294 1.39 0.57 3.39 PRS_PLINK_0.0199526231496888 TRUE 362.9 Retinal edema Both 34 629 7 sense organs darkseagreen4 629, 34 158, 6 157, 3 157, 12 157, 13 0.41 0.179 0.0222 1.653 1.51 1.06 2.14 -0.454 0.599 0.448 0.3485 0.635 0.196 2.05 0.699 0.486 0.15 0.8237 2.01 0.776 5.22 0.802 0.502 0.11 0.9579 2.23 0.834 5.97 PRS_PLINK_0.0199526231496888 TRUE 363 Chorioretinal inflammations, scars, and other disorders of choroid Both 107 1008 7 sense organs darkseagreen4 1008, 107 252, 26 252, 29 252, 35 252, 17 -0.12 0.104 0.246 0.6088 0.887 0.724 1.09 0.0678 0.281 0.809 0.09204 1.07 0.618 1.85 0.26 0.275 0.345 0.4628 1.3 0.757 2.22 -0.402 0.334 0.229 0.6404 0.669 0.348 1.29 PRS_PLINK_0.0199526231496888 FALSE 363.3 Chorioretinal scars Both 70 664 7 sense organs darkseagreen4 664, 70 166, 13 166, 23 166, 24 166, 10 -0.195 0.13 0.133 0.877 0.823 0.638 1.06 0.491 0.354 0.166 0.7795 1.63 0.816 3.27 0.653 0.36 0.0701 1.154 1.92 0.948 3.89 -0.522 0.434 0.229 0.6411 0.593 0.254 1.39 PRS_PLINK_0.0199526231496888 FALSE 364 Corneal opacity and other disorders of cornea Both 231 2495 7 sense organs darkseagreen4 2495, 231 624, 65 624, 63 623, 67 624, 36 -0.102 0.0715 0.154 0.8135 0.903 0.785 1.04 -0.0201 0.185 0.914 0.03922 0.98 0.682 1.41 0.0939 0.185 0.612 0.2131 1.1 0.764 1.58 -0.536 0.224 0.0167 1.779 0.585 0.377 0.907 PRS_PLINK_0.0199526231496888 FALSE 364.1 Corneal opacity Both 85 931 7 sense organs darkseagreen4 931, 85 233, 20 233, 19 232, 31 233, 15 0.0345 0.119 0.772 0.1126 1.04 0.82 1.31 -0.0922 0.327 0.778 0.1091 0.912 0.481 1.73 0.394 0.301 0.19 0.7209 1.48 0.822 2.68 -0.244 0.359 0.497 0.3038 0.784 0.388 1.58 PRS_PLINK_0.0199526231496888 FALSE 364.2 Corneal edema Both 27 292 7 sense organs darkseagreen4 292, 27 73, 8 73, 6 73, 10 73, 3 -0.171 0.197 0.387 0.412 0.843 0.572 1.24 -0.144 0.539 0.79 0.1025 0.866 0.301 2.49 0.293 0.498 0.557 0.2543 1.34 0.505 3.56 -0.638 0.645 0.323 0.4911 0.528 0.149 1.87 PRS_PLINK_0.0199526231496888 TRUE 364.4 Corneal degenerations Both 94 990 7 sense organs darkseagreen4 990, 94 248, 31 247, 24 247, 23 248, 16 -0.173 0.11 0.116 0.9374 0.841 0.678 1.04 -0.259 0.282 0.36 0.4441 0.772 0.444 1.34 -0.234 0.289 0.417 0.3794 0.791 0.449 1.39 -0.714 0.328 0.0294 1.532 0.49 0.258 0.931 PRS_PLINK_0.0199526231496888 FALSE 364.41 Keratoconus Both 20 187 7 sense organs darkseagreen4 187, 20 47, 6 47, 5 46, 3 47, 6 -0.0581 0.224 0.795 0.09964 0.944 0.609 1.46 -0.258 0.633 0.683 0.1655 0.772 0.224 2.67 -0.737 0.685 0.282 0.5504 0.478 0.125 1.83 0.256 0.645 0.692 0.1601 1.29 0.365 4.57 PRS_PLINK_0.0199526231496888 TRUE 364.5 Corneal dystrophy Both 84 866 7 sense organs darkseagreen4 866, 84 217, 17 216, 23 216, 29 217, 15 0.035 0.117 0.765 0.1163 1.04 0.823 1.3 0.316 0.322 0.327 0.4851 1.37 0.729 2.58 0.658 0.319 0.0391 1.407 1.93 1.03 3.61 -0.048 0.372 0.897 0.04701 0.953 0.46 1.98 PRS_PLINK_0.0199526231496888 FALSE 364.51 Fuchs' dystrophy Both 54 464 7 sense organs darkseagreen4 464, 54 116, 13 116, 12 116, 18 116, 11 0.0424 0.147 0.773 0.1116 1.04 0.782 1.39 -0.00013 0.403 1 0.000112 1 0.453 2.2 0.5 0.393 0.202 0.6937 1.65 0.764 3.56 -0.0638 0.433 0.883 0.05413 0.938 0.402 2.19 PRS_PLINK_0.0199526231496888 FALSE 364.9 Cornea replaced by transplant Both 22 164 7 sense organs darkseagreen4 164, 22 41, 4 41, 9 41, 6 41, 3 -0.355 0.251 0.158 0.8009 0.701 0.428 1.15 0.749 0.621 0.228 0.643 2.12 0.627 7.14 0.348 0.652 0.594 0.2264 1.42 0.395 5.08 -0.339 0.788 0.667 0.176 0.712 0.152 3.34 PRS_PLINK_0.0199526231496888 TRUE 365 Glaucoma Both 467 4682 7 sense organs darkseagreen4 4682, 467 1171, 113 1170, 117 1170, 117 1171, 119 -0.00845 0.0495 0.865 0.0632 0.992 0.9 1.09 0.0523 0.139 0.706 0.1511 1.05 0.803 1.38 0.0878 0.14 0.531 0.2751 1.09 0.83 1.44 0.0781 0.144 0.588 0.2306 1.08 0.815 1.43 PRS_PLINK_0.0199526231496888 FALSE 365.1 Open-angle glaucoma Both 108 1195 7 sense organs darkseagreen4 1195, 108 299, 22 299, 25 298, 24 299, 37 0.0918 0.103 0.375 0.4261 1.1 0.895 1.34 0.0858 0.297 0.772 0.1121 1.09 0.609 1.95 0.141 0.3 0.639 0.1946 1.15 0.64 2.07 0.463 0.284 0.103 0.9873 1.59 0.911 2.77 PRS_PLINK_0.0199526231496888 FALSE 365.11 Primary open angle glaucoma Both 47 631 7 sense organs darkseagreen4 631, 47 158, 10 158, 11 157, 10 158, 16 0.161 0.153 0.294 0.5321 1.17 0.87 1.59 0.0147 0.429 0.973 0.01208 1.01 0.438 2.35 0.142 0.433 0.744 0.1285 1.15 0.493 2.69 0.329 0.411 0.424 0.3724 1.39 0.62 3.11 PRS_PLINK_0.0199526231496888 TRUE 365.2 Primary angle-closure glaucoma Both 34 467 7 sense organs darkseagreen4 467, 34 117, 9 117, 8 116, 11 117, 6 -0.007 0.176 0.968 0.01403 0.993 0.704 1.4 -0.104 0.478 0.828 0.08218 0.901 0.353 2.3 0.29 0.456 0.526 0.2794 1.34 0.546 3.27 -0.155 0.553 0.779 0.1083 0.856 0.29 2.53 PRS_PLINK_0.0199526231496888 TRUE 366 Cataract Both 1475 6983 7 sense organs darkseagreen4 6983, 1475 1746, 408 1746, 361 1745, 369 1746, 336 -0.0186 0.0313 0.551 0.2588 0.982 0.923 1.04 -0.0652 0.0865 0.451 0.3458 0.937 0.791 1.11 -0.0454 0.0856 0.596 0.2245 0.956 0.808 1.13 -0.131 0.0898 0.145 0.8398 0.877 0.736 1.05 PRS_PLINK_0.0199526231496888 FALSE 366.1 Nonsenile Cataract Both 36 375 7 sense organs darkseagreen4 375, 36 94, 13 94, 7 93, 8 94, 8 -0.136 0.19 0.472 0.3262 0.873 0.602 1.27 -0.792 0.499 0.113 0.9477 0.453 0.17 1.21 -0.366 0.462 0.428 0.3682 0.694 0.28 1.72 -0.395 0.488 0.419 0.3782 0.674 0.259 1.75 PRS_PLINK_0.0199526231496888 TRUE 366.2 Senile cataract Both 915 5857 7 sense organs darkseagreen4 5857, 915 1465, 256 1464, 216 1464, 233 1464, 210 -0.0277 0.038 0.466 0.3314 0.973 0.903 1.05 -0.13 0.106 0.217 0.6635 0.878 0.714 1.08 -0.0796 0.104 0.443 0.3538 0.923 0.754 1.13 -0.157 0.109 0.15 0.8252 0.854 0.69 1.06 PRS_PLINK_0.0199526231496888 FALSE 367 Disorders of refraction and accommodation; blindness and low vision Both 2289 10543 7 sense organs darkseagreen4 10543, 2289 2635, 618 2636, 582 2635, 560 2636, 529 -0.031 0.0244 0.203 0.6915 0.969 0.924 1.02 -0.0219 0.0656 0.739 0.1314 0.978 0.86 1.11 -0.0593 0.0673 0.378 0.4226 0.942 0.826 1.08 -0.066 0.0703 0.348 0.4589 0.936 0.816 1.07 PRS_PLINK_0.0199526231496888 FALSE 367.1 Myopia Both 1412 9925 7 sense organs darkseagreen4 9925, 1412 2481, 371 2481, 376 2481, 343 2481, 322 -0.0289 0.0301 0.337 0.4728 0.971 0.916 1.03 0.0549 0.0802 0.494 0.3064 1.06 0.903 1.24 -0.0353 0.0833 0.672 0.1728 0.965 0.82 1.14 -0.0627 0.0873 0.473 0.3255 0.939 0.792 1.11 PRS_PLINK_0.0199526231496888 FALSE 367.2 Astigmatism Both 1045 9032 7 sense organs darkseagreen4 9032, 1045 2257, 286 2258, 258 2258, 263 2258, 238 -0.0423 0.0343 0.217 0.6628 0.959 0.896 1.03 -0.0815 0.0923 0.378 0.423 0.922 0.769 1.1 -0.0577 0.0934 0.536 0.2705 0.944 0.786 1.13 -0.11 0.0982 0.264 0.5778 0.896 0.739 1.09 PRS_PLINK_0.0199526231496888 FALSE 367.8 Hypermetropia Both 481 4557 7 sense organs darkseagreen4 4557, 481 1139, 139 1139, 110 1139, 110 1139, 122 -0.0446 0.0493 0.366 0.4371 0.956 0.868 1.05 -0.204 0.135 0.13 0.8865 0.815 0.626 1.06 -0.194 0.137 0.156 0.807 0.824 0.63 1.08 -0.0351 0.137 0.798 0.09791 0.966 0.738 1.26 PRS_PLINK_0.0199526231496888 FALSE 367.9 Blindness and low vision Both 315 3028 7 sense organs darkseagreen4 3028, 315 757, 82 757, 70 757, 82 757, 81 0.0271 0.0616 0.66 0.1803 1.03 0.911 1.16 -0.15 0.17 0.376 0.4245 0.86 0.617 1.2 0.0239 0.166 0.885 0.05287 1.02 0.74 1.42 0.00908 0.173 0.958 0.01859 1.01 0.719 1.42 PRS_PLINK_0.0199526231496888 FALSE 368 Visual disturbances Both 1470 10996 7 sense organs darkseagreen4 10996, 1470 2749, 390 2749, 364 2749, 356 2749, 359 -0.00673 0.0287 0.815 0.08904 0.993 0.939 1.05 -0.0408 0.0784 0.603 0.2196 0.96 0.823 1.12 -0.0731 0.0798 0.36 0.4439 0.93 0.795 1.09 -0.0162 0.0822 0.844 0.0738 0.984 0.838 1.16 PRS_PLINK_0.0199526231496888 FALSE 368.1 Amblyopia Both 156 1765 7 sense organs darkseagreen4 1765, 156 442, 37 441, 41 441, 41 441, 37 0.0275 0.0833 0.741 0.1302 1.03 0.873 1.21 0.0859 0.234 0.713 0.1469 1.09 0.689 1.72 0.0856 0.235 0.716 0.1452 1.09 0.687 1.73 0.0311 0.251 0.901 0.04514 1.03 0.631 1.69 PRS_PLINK_0.0199526231496888 FALSE 368.2 Diplopia and disorders of binocular vision Both 265 2545 7 sense organs darkseagreen4 2545, 265 637, 82 636, 66 636, 65 636, 52 -0.171 0.0657 0.0093 2.032 0.843 0.741 0.959 -0.205 0.174 0.239 0.6221 0.815 0.58 1.15 -0.225 0.176 0.202 0.6938 0.799 0.565 1.13 -0.436 0.194 0.0244 1.613 0.647 0.443 0.945 PRS_PLINK_0.0199526231496888 FALSE 368.3 Anisometropia Both 60 565 7 sense organs darkseagreen4 565, 60 142, 22 141, 8 141, 15 141, 15 -0.0872 0.141 0.536 0.271 0.917 0.696 1.21 -0.831 0.417 0.0464 1.333 0.436 0.192 0.987 -0.235 0.356 0.51 0.2928 0.791 0.394 1.59 -0.329 0.375 0.38 0.4203 0.72 0.345 1.5 PRS_PLINK_0.0199526231496888 FALSE 368.4 Visual field defects Both 220 2477 7 sense organs darkseagreen4 2477, 220 620, 54 619, 55 619, 60 619, 51 -0.0229 0.0729 0.753 0.123 0.977 0.847 1.13 0.066 0.199 0.74 0.1305 1.07 0.723 1.58 0.0978 0.196 0.617 0.2096 1.1 0.751 1.62 0.0185 0.21 0.93 0.03175 1.02 0.675 1.54 PRS_PLINK_0.0199526231496888 FALSE 368.9 Subjective visual disturbances Both 280 2728 7 sense organs darkseagreen4 2728, 280 682, 72 682, 66 682, 80 682, 62 -0.021 0.0645 0.745 0.1279 0.979 0.863 1.11 -0.0639 0.178 0.719 0.1431 0.938 0.662 1.33 0.134 0.172 0.436 0.3604 1.14 0.816 1.6 -0.126 0.19 0.507 0.2953 0.882 0.608 1.28 PRS_PLINK_0.0199526231496888 FALSE 368.91 Psychophysical visual disturbances Both 28 236 7 sense organs darkseagreen4 236, 28 59, 10 59, 3 59, 9 59, 6 0.064 0.218 0.769 0.1138 1.07 0.695 1.64 -0.998 0.637 0.118 0.9297 0.369 0.106 1.29 -0.0971 0.503 0.847 0.07215 0.907 0.338 2.43 -0.435 0.566 0.442 0.3543 0.647 0.213 1.96 PRS_PLINK_0.0199526231496888 TRUE 369 Infection of the eye Both 937 8460 7 sense organs darkseagreen4 8460, 937 2114, 272 2115, 223 2115, 239 2115, 203 -0.0995 0.0359 0.00555 2.256 0.905 0.844 0.971 -0.183 0.096 0.0563 1.25 0.832 0.69 1 -0.134 0.0958 0.162 0.7903 0.875 0.725 1.06 -0.295 0.103 0.00407 2.39 0.745 0.609 0.911 PRS_PLINK_0.0199526231496888 FALSE 369.2 Eye infection, viral Both 141 1373 7 sense organs darkseagreen4 1373, 141 344, 40 343, 37 343, 39 343, 25 -0.135 0.0907 0.137 0.8643 0.874 0.731 1.04 -0.0399 0.238 0.867 0.06193 0.961 0.602 1.53 -0.0197 0.239 0.934 0.02961 0.98 0.614 1.57 -0.478 0.27 0.0765 1.117 0.62 0.365 1.05 PRS_PLINK_0.0199526231496888 FALSE 369.5 Conjunctivitis, infectious Both 813 7587 7 sense organs darkseagreen4 7587, 813 1896, 235 1897, 195 1896, 202 1897, 181 -0.0927 0.0384 0.0156 1.806 0.911 0.845 0.983 -0.169 0.103 0.101 0.9969 0.845 0.691 1.03 -0.153 0.103 0.138 0.8616 0.858 0.701 1.05 -0.259 0.109 0.0177 1.751 0.772 0.623 0.956 PRS_PLINK_0.0199526231496888 FALSE 370 Keratitis Both 330 3350 7 sense organs darkseagreen4 3350, 330 838, 104 837, 83 837, 76 838, 67 -0.149 0.0593 0.0121 1.918 0.862 0.767 0.968 -0.177 0.156 0.255 0.5941 0.837 0.617 1.14 -0.283 0.161 0.0776 1.11 0.753 0.55 1.03 -0.381 0.171 0.0258 1.588 0.683 0.489 0.955 PRS_PLINK_0.0199526231496888 FALSE 370.1 Corneal ulcer Both 61 634 7 sense organs darkseagreen4 634, 61 159, 20 158, 16 158, 12 159, 13 -0.168 0.133 0.206 0.6857 0.845 0.651 1.1 -0.0565 0.352 0.873 0.05919 0.945 0.474 1.88 -0.494 0.368 0.18 0.7456 0.61 0.296 1.26 -0.39 0.375 0.298 0.5253 0.677 0.324 1.41 PRS_PLINK_0.0199526231496888 FALSE 370.2 Superficial keratitis Both 137 1276 7 sense organs darkseagreen4 1276, 137 319, 38 319, 39 319, 34 319, 26 -0.121 0.092 0.187 0.7287 0.886 0.74 1.06 0.104 0.242 0.668 0.1752 1.11 0.69 1.78 -0.0997 0.251 0.691 0.1607 0.905 0.554 1.48 -0.334 0.278 0.229 0.6404 0.716 0.415 1.23 PRS_PLINK_0.0199526231496888 FALSE 370.3 Keratoconjunctivitis Both 140 1508 7 sense organs darkseagreen4 1508, 140 377, 49 377, 31 377, 29 377, 31 -0.217 0.0927 0.0195 1.709 0.805 0.671 0.966 -0.428 0.238 0.0726 1.139 0.652 0.409 1.04 -0.488 0.246 0.0476 1.322 0.614 0.379 0.995 -0.455 0.249 0.068 1.168 0.634 0.389 1.03 PRS_PLINK_0.0199526231496888 FALSE 370.31 Keratoconjunctivitis sicca Both 37 403 7 sense organs darkseagreen4 403, 37 101, 13 101, 7 100, 8 101, 9 0.00442 0.18 0.98 0.008587 1 0.706 1.43 -0.517 0.46 0.26 0.5843 0.596 0.242 1.47 -0.406 0.459 0.376 0.4244 0.666 0.271 1.64 -0.223 0.447 0.618 0.2091 0.8 0.333 1.92 PRS_PLINK_0.0199526231496888 TRUE 371 Inflammation of the eye Both 1063 8629 7 sense organs darkseagreen4 8629, 1063 2157, 283 2157, 264 2157, 265 2157, 251 -0.0399 0.0336 0.234 0.6304 0.961 0.9 1.03 -0.0318 0.0919 0.729 0.1373 0.969 0.809 1.16 -0.0316 0.0927 0.733 0.1346 0.969 0.808 1.16 -0.0535 0.0967 0.58 0.2363 0.948 0.784 1.15 PRS_PLINK_0.0199526231496888 FALSE 371.1 Uveitis, noninfectious or NOS Both 121 1278 7 sense organs darkseagreen4 1278, 121 320, 37 319, 31 319, 27 320, 26 -0.189 0.096 0.0491 1.309 0.828 0.686 0.999 -0.191 0.253 0.449 0.3473 0.826 0.503 1.36 -0.311 0.265 0.24 0.6192 0.732 0.436 1.23 -0.463 0.275 0.0927 1.033 0.63 0.367 1.08 PRS_PLINK_0.0199526231496888 FALSE 371.2 Conjunctivitis, noninfectious Both 233 2543 7 sense organs darkseagreen4 2543, 233 635, 68 636, 53 635, 63 636, 49 -0.0944 0.0704 0.18 0.7444 0.91 0.793 1.04 -0.241 0.191 0.207 0.6834 0.786 0.541 1.14 -0.047 0.185 0.8 0.09706 0.954 0.664 1.37 -0.311 0.202 0.124 0.905 0.733 0.493 1.09 PRS_PLINK_0.0199526231496888 FALSE 371.21 Allergic conjunctivitis Both 197 2168 7 sense organs darkseagreen4 2168, 197 541, 58 542, 43 542, 57 542, 39 -0.0861 0.0756 0.255 0.5933 0.918 0.791 1.06 -0.284 0.209 0.173 0.7607 0.753 0.5 1.13 -0.00305 0.197 0.988 0.005391 0.997 0.678 1.47 -0.437 0.221 0.0479 1.32 0.646 0.419 0.996 PRS_PLINK_0.0199526231496888 FALSE 371.3 Inflammation of eyelids Both 786 6730 7 sense organs darkseagreen4 6730, 786 1682, 203 1682, 192 1682, 196 1683, 195 -0.0163 0.0389 0.674 0.1711 0.984 0.912 1.06 -0.0364 0.107 0.735 0.134 0.964 0.781 1.19 -0.00965 0.108 0.929 0.03215 0.99 0.802 1.22 0.0167 0.112 0.882 0.05473 1.02 0.817 1.27 PRS_PLINK_0.0199526231496888 FALSE 371.33 Noninfectious dermatoses of eyelid Both 40 370 7 sense organs darkseagreen4 370, 40 93, 8 92, 9 92, 13 93, 10 0.0584 0.163 0.721 0.142 1.06 0.769 1.46 0.059 0.486 0.903 0.04412 1.06 0.409 2.75 0.443 0.456 0.332 0.4794 1.56 0.637 3.81 0.136 0.491 0.782 0.1069 1.15 0.438 3 PRS_PLINK_0.0199526231496888 TRUE 372 Disorders of conjunctiva Both 211 2391 7 sense organs darkseagreen4 2391, 211 598, 48 598, 62 597, 44 598, 57 0.0168 0.0735 0.82 0.08644 1.02 0.88 1.17 0.267 0.201 0.184 0.7345 1.31 0.881 1.94 -0.138 0.218 0.528 0.2776 0.872 0.569 1.34 0.195 0.212 0.356 0.448 1.22 0.803 1.84 PRS_PLINK_0.0199526231496888 FALSE 374 Other disorders of eyelids Both 589 5790 7 sense organs darkseagreen4 5790, 589 1447, 175 1447, 143 1447, 131 1448, 140 -0.093 0.0444 0.0361 1.442 0.911 0.835 0.994 -0.188 0.119 0.113 0.9459 0.828 0.656 1.05 -0.291 0.123 0.0182 1.74 0.748 0.587 0.952 -0.181 0.124 0.145 0.8399 0.834 0.654 1.06 PRS_PLINK_0.0199526231496888 FALSE 374.1 Ectropion or entropion Both 70 797 7 sense organs darkseagreen4 797, 70 199, 25 199, 14 199, 18 199, 13 -0.27 0.125 0.031 1.509 0.763 0.597 0.976 -0.56 0.339 0.0992 1.004 0.571 0.294 1.11 -0.431 0.33 0.192 0.7178 0.65 0.34 1.24 -0.858 0.362 0.018 1.745 0.424 0.209 0.863 PRS_PLINK_0.0199526231496888 FALSE 374.2 Lagophthalmos Both 53 577 7 sense organs darkseagreen4 577, 53 145, 19 144, 11 144, 15 144, 8 -0.317 0.149 0.0329 1.483 0.728 0.544 0.975 -0.507 0.389 0.193 0.7153 0.602 0.281 1.29 -0.278 0.369 0.451 0.3454 0.757 0.368 1.56 -0.845 0.434 0.0515 1.288 0.429 0.183 1.01 PRS_PLINK_0.0199526231496888 FALSE 374.3 Ptosis of eyelid Both 195 2277 7 sense organs darkseagreen4 2277, 195 570, 47 569, 50 569, 50 569, 48 0.0077 0.0771 0.92 0.03599 1.01 0.866 1.17 0.102 0.211 0.628 0.2018 1.11 0.732 1.67 0.0414 0.214 0.846 0.07238 1.04 0.686 1.58 -0.0477 0.224 0.831 0.08032 0.953 0.615 1.48 PRS_PLINK_0.0199526231496888 FALSE 374.6 Dermatochalasis Both 171 1856 7 sense organs darkseagreen4 1856, 171 464, 47 464, 45 464, 45 464, 34 -0.0883 0.0828 0.287 0.5427 0.916 0.778 1.08 -0.053 0.219 0.809 0.09199 0.948 0.617 1.46 -0.0385 0.222 0.862 0.06427 0.962 0.622 1.49 -0.291 0.24 0.226 0.6457 0.748 0.467 1.2 PRS_PLINK_0.0199526231496888 FALSE 375 Disorders of lacrimal system Both 837 6858 7 sense organs darkseagreen4 6858, 837 1715, 237 1714, 199 1714, 210 1715, 191 -0.0406 0.038 0.285 0.5447 0.96 0.891 1.03 -0.12 0.103 0.244 0.613 0.886 0.724 1.09 -0.0923 0.103 0.371 0.4306 0.912 0.745 1.12 -0.143 0.109 0.192 0.7158 0.867 0.7 1.07 PRS_PLINK_0.0199526231496888 FALSE 375.1 Dry eyes Both 909 7100 7 sense organs darkseagreen4 7100, 909 1775, 256 1775, 217 1775, 234 1775, 202 -0.0451 0.0367 0.219 0.6586 0.956 0.889 1.03 -0.11 0.0997 0.268 0.5721 0.895 0.737 1.09 -0.0562 0.0988 0.57 0.2445 0.945 0.779 1.15 -0.158 0.106 0.135 0.871 0.853 0.693 1.05 PRS_PLINK_0.0199526231496888 FALSE 375.2 Epiphora Both 95 1044 7 sense organs darkseagreen4 1044, 95 261, 30 261, 29 261, 18 261, 18 -0.166 0.109 0.13 0.8855 0.847 0.684 1.05 -0.0913 0.273 0.738 0.1318 0.913 0.534 1.56 -0.451 0.305 0.139 0.8565 0.637 0.35 1.16 -0.44 0.318 0.167 0.7767 0.644 0.345 1.2 PRS_PLINK_0.0199526231496888 FALSE 376 Disorders of the orbit Both 90 944 7 sense organs darkseagreen4 944, 90 236, 25 236, 27 236, 17 236, 21 -0.141 0.112 0.207 0.6844 0.868 0.698 1.08 0.0413 0.286 0.885 0.05299 1.04 0.595 1.83 -0.452 0.326 0.165 0.7829 0.636 0.336 1.2 -0.183 0.313 0.56 0.2518 0.833 0.451 1.54 PRS_PLINK_0.0199526231496888 FALSE 377 Disorders of optic nerve and visual pathways Both 221 2417 7 sense organs darkseagreen4 2417, 221 605, 43 604, 56 604, 58 604, 63 0.109 0.0719 0.129 0.8895 1.12 0.969 1.28 0.262 0.208 0.209 0.6796 1.3 0.864 1.95 0.279 0.208 0.181 0.7433 1.32 0.879 1.99 0.453 0.217 0.0366 1.436 1.57 1.03 2.4 PRS_PLINK_0.0199526231496888 FALSE 377.1 Optic atrophy Both 73 677 7 sense organs darkseagreen4 677, 73 170, 13 169, 24 169, 22 169, 13 -0.0287 0.123 0.815 0.08889 0.972 0.764 1.24 0.606 0.353 0.0858 1.066 1.83 0.918 3.66 0.471 0.357 0.187 0.728 1.6 0.795 3.23 0.176 0.42 0.675 0.1709 1.19 0.523 2.72 PRS_PLINK_0.0199526231496888 FALSE 377.3 Optic neuritis/neuropathy Both 139 1583 7 sense organs darkseagreen4 1583, 139 396, 30 396, 28 395, 34 396, 47 0.209 0.0899 0.02 1.698 1.23 1.03 1.47 -0.0478 0.265 0.857 0.06704 0.953 0.567 1.6 0.117 0.256 0.648 0.1881 1.12 0.68 1.86 0.489 0.254 0.0547 1.262 1.63 0.99 2.68 PRS_PLINK_0.0199526231496888 FALSE 378 Strabismus and other disorders of binocular eye movements Both 321 3260 7 sense organs darkseagreen4 3260, 321 815, 92 815, 79 815, 83 815, 67 -0.0925 0.0607 0.127 0.8949 0.912 0.809 1.03 -0.142 0.161 0.378 0.423 0.867 0.632 1.19 -0.0893 0.161 0.58 0.2363 0.915 0.666 1.26 -0.251 0.177 0.156 0.8061 0.778 0.55 1.1 PRS_PLINK_0.0199526231496888 FALSE 378.1 Strabismus (not specified as paralytic) Both 212 2148 7 sense organs darkseagreen4 2148, 212 537, 61 537, 54 537, 52 537, 45 -0.146 0.0741 0.0486 1.314 0.864 0.747 0.999 -0.0821 0.197 0.676 0.1698 0.921 0.626 1.35 -0.158 0.2 0.429 0.3674 0.854 0.577 1.26 -0.248 0.215 0.248 0.6049 0.78 0.512 1.19 PRS_PLINK_0.0199526231496888 FALSE 378.2 Nystagmus and other irregular eye movements Both 48 472 7 sense organs darkseagreen4 472, 48 118, 10 118, 12 118, 16 118, 10 0.0588 0.151 0.696 0.1572 1.06 0.789 1.42 0.234 0.43 0.586 0.2323 1.26 0.544 2.93 0.481 0.426 0.259 0.5865 1.62 0.702 3.73 0.241 0.466 0.605 0.2185 1.27 0.511 3.17 PRS_PLINK_0.0199526231496888 TRUE 378.5 Paralytic strabismus Both 79 857 7 sense organs darkseagreen4 857, 79 215, 23 214, 20 214, 25 214, 11 -0.2 0.12 0.0942 1.026 0.818 0.647 1.03 -0.249 0.318 0.434 0.3621 0.78 0.418 1.45 0.0411 0.305 0.893 0.04928 1.04 0.573 1.89 -0.776 0.386 0.0443 1.354 0.46 0.216 0.98 PRS_PLINK_0.0199526231496888 FALSE 379 Other disorders of eye Both 997 7637 7 sense organs darkseagreen4 7637, 997 1910, 274 1909, 225 1909, 261 1909, 236 0.00753 0.0351 0.83 0.08075 1.01 0.941 1.08 -0.15 0.0975 0.124 0.9067 0.861 0.711 1.04 -0.0189 0.0953 0.843 0.07418 0.981 0.814 1.18 -0.0647 0.1 0.519 0.2847 0.937 0.77 1.14 PRS_PLINK_0.0199526231496888 FALSE 379.1 Scleritis and episcleritis Both 49 502 7 sense organs darkseagreen4 502, 49 126, 10 125, 10 125, 13 126, 16 0.197 0.152 0.195 0.7108 1.22 0.904 1.64 -0.0076 0.426 0.986 0.006229 0.992 0.431 2.29 0.206 0.425 0.627 0.2025 1.23 0.535 2.82 0.462 0.423 0.274 0.5617 1.59 0.693 3.63 PRS_PLINK_0.0199526231496888 TRUE 379.2 Disorders of vitreous body Both 649 5308 7 sense organs darkseagreen4 5308, 649 1327, 176 1327, 166 1327, 155 1327, 151 -0.0102 0.0432 0.814 0.08964 0.99 0.909 1.08 -0.00549 0.117 0.963 0.01658 0.995 0.791 1.25 -0.0953 0.12 0.427 0.3699 0.909 0.719 1.15 -0.0358 0.124 0.773 0.1116 0.965 0.756 1.23 PRS_PLINK_0.0199526231496888 FALSE 379.3 Aphakia and other disorders of lens Both 29 238 7 sense organs darkseagreen4 238, 29 60, 12 59, 6 59, 7 60, 4 -0.394 0.204 0.0533 1.273 0.674 0.452 1.01 -0.52 0.509 0.307 0.5129 0.595 0.219 1.61 -0.432 0.493 0.381 0.4193 0.649 0.247 1.71 -0.804 0.603 0.182 0.7391 0.448 0.137 1.46 PRS_PLINK_0.0199526231496888 TRUE 379.4 Anomalies of pupillary function Both 64 707 7 sense organs darkseagreen4 707, 64 177, 15 177, 12 176, 18 177, 19 0.114 0.134 0.398 0.4003 1.12 0.861 1.46 -0.158 0.38 0.678 0.1686 0.854 0.406 1.8 0.286 0.361 0.428 0.369 1.33 0.656 2.7 0.188 0.356 0.598 0.2233 1.21 0.601 2.42 PRS_PLINK_0.0199526231496888 FALSE 379.5 Disorders of iris and ciliary body Both 59 676 7 sense organs darkseagreen4 676, 59 169, 16 169, 14 169, 13 169, 16 -0.0203 0.142 0.886 0.05237 0.98 0.741 1.3 -0.0132 0.372 0.972 0.01242 0.987 0.476 2.05 -0.153 0.389 0.695 0.1579 0.859 0.4 1.84 0.164 0.371 0.658 0.1816 1.18 0.569 2.44 PRS_PLINK_0.0199526231496888 FALSE 379.51 Pigmentary iris degeneration Both 18 190 7 sense organs darkseagreen4 190, 18 48, 3 47, 3 47, 5 48, 7 0.322 0.284 0.257 0.5905 1.38 0.791 2.41 0.141 0.73 0.847 0.07206 1.15 0.275 4.82 0.434 0.682 0.525 0.2797 1.54 0.405 5.88 0.748 0.707 0.29 0.5376 2.11 0.529 8.44 PRS_PLINK_0.0199526231496888 TRUE 379.9 Pain, swelling or discharge of eye Both 322 3215 7 sense organs darkseagreen4 3215, 322 804, 88 804, 83 803, 75 804, 76 -0.0581 0.0616 0.345 0.4619 0.944 0.836 1.06 -0.0496 0.161 0.758 0.1203 0.952 0.694 1.31 -0.165 0.167 0.324 0.489 0.848 0.611 1.18 -0.081 0.172 0.638 0.1952 0.922 0.658 1.29 PRS_PLINK_0.0199526231496888 FALSE 380 Disorders of external ear Both 528 4615 7 sense organs darkseagreen4 4615, 528 1153, 160 1154, 111 1153, 129 1154, 128 -0.0548 0.0477 0.251 0.6008 0.947 0.862 1.04 -0.37 0.131 0.00463 2.334 0.691 0.535 0.892 -0.209 0.127 0.1 1 0.811 0.632 1.04 -0.201 0.132 0.128 0.8919 0.818 0.631 1.06 PRS_PLINK_0.0199526231496888 FALSE 380.1 Otitis externa Both 389 4124 7 sense organs darkseagreen4 4124, 389 1030, 104 1031, 98 1031, 79 1031, 108 -0.0611 0.0552 0.268 0.5711 0.941 0.844 1.05 -0.0621 0.148 0.674 0.1711 0.94 0.704 1.26 -0.284 0.157 0.0711 1.148 0.753 0.553 1.02 0.0412 0.152 0.787 0.104 1.04 0.773 1.4 PRS_PLINK_0.0199526231496888 FALSE 380.4 Impacted cerumen Both 634 5538 7 sense organs darkseagreen4 5538, 634 1384, 178 1384, 159 1384, 145 1385, 152 -0.0417 0.0434 0.336 0.4733 0.959 0.881 1.04 -0.101 0.116 0.385 0.4141 0.904 0.72 1.14 -0.196 0.12 0.103 0.9881 0.822 0.649 1.04 -0.119 0.123 0.333 0.4777 0.888 0.698 1.13 PRS_PLINK_0.0199526231496888 FALSE 381 Otitis media and Eustachian tube disorders Both 1259 10333 7 sense organs darkseagreen4 10333, 1259 2583, 342 2583, 309 2583, 285 2583, 323 -0.0273 0.031 0.379 0.4208 0.973 0.916 1.03 -0.0984 0.084 0.241 0.6176 0.906 0.769 1.07 -0.183 0.0867 0.0347 1.46 0.833 0.703 0.987 -0.0112 0.087 0.898 0.04694 0.989 0.834 1.17 PRS_PLINK_0.0199526231496888 FALSE 381.1 Otitis media Both 918 9055 7 sense organs darkseagreen4 9055, 918 2263, 248 2264, 233 2263, 203 2264, 234 -0.0243 0.0359 0.498 0.3026 0.976 0.91 1.05 -0.0669 0.0965 0.488 0.3114 0.935 0.774 1.13 -0.205 0.101 0.0421 1.376 0.814 0.668 0.993 -0.0245 0.101 0.808 0.09272 0.976 0.801 1.19 PRS_PLINK_0.0199526231496888 FALSE 381.11 Suppurative and unspecified otitis media Both 778 7895 7 sense organs darkseagreen4 7895, 778 1973, 217 1974, 194 1973, 164 1974, 203 -0.034 0.039 0.383 0.4166 0.967 0.895 1.04 -0.115 0.104 0.268 0.5712 0.891 0.727 1.09 -0.295 0.11 0.00727 2.138 0.744 0.6 0.923 -0.0401 0.107 0.709 0.1494 0.961 0.778 1.19 PRS_PLINK_0.0199526231496888 FALSE 381.2 Eustachian tube disorders Both 528 5207 7 sense organs darkseagreen4 5207, 528 1302, 160 1302, 132 1301, 107 1302, 129 -0.0892 0.0476 0.061 1.214 0.915 0.833 1 -0.179 0.124 0.15 0.8234 0.836 0.656 1.07 -0.381 0.133 0.00412 2.386 0.683 0.527 0.886 -0.171 0.131 0.192 0.7167 0.843 0.653 1.09 PRS_PLINK_0.0199526231496888 FALSE 381.3 Mastoiditis & related conditions Both 41 441 7 sense organs darkseagreen4 441, 41 111, 7 110, 17 110, 8 110, 9 0.0339 0.168 0.84 0.07593 1.03 0.745 1.44 0.771 0.44 0.08 1.097 2.16 0.912 5.13 0.00816 0.499 0.987 0.005708 1.01 0.379 2.68 0.237 0.516 0.647 0.1893 1.27 0.461 3.48 PRS_PLINK_0.0199526231496888 TRUE 381.9 Otorrhea Both 103 1016 7 sense organs darkseagreen4 1016, 103 254, 21 254, 23 254, 26 254, 33 0.188 0.107 0.0793 1.101 1.21 0.978 1.49 0.183 0.313 0.559 0.2527 1.2 0.65 2.22 0.201 0.308 0.514 0.2891 1.22 0.669 2.24 0.458 0.305 0.133 0.8774 1.58 0.87 2.87 PRS_PLINK_0.0199526231496888 FALSE 382 Otalgia Both 610 5920 7 sense organs darkseagreen4 5920, 610 1479, 164 1480, 145 1480, 144 1480, 157 -0.0431 0.0444 0.331 0.4795 0.958 0.878 1.04 -0.13 0.12 0.277 0.5574 0.878 0.694 1.11 -0.189 0.122 0.123 0.9084 0.828 0.651 1.05 -0.0766 0.123 0.534 0.2725 0.926 0.728 1.18 PRS_PLINK_0.0199526231496888 FALSE 383 Otosclerosis Both 35 369 7 sense organs darkseagreen4 369, 35 93, 15 92, 9 92, 6 92, 5 -0.402 0.177 0.0231 1.636 0.669 0.473 0.946 -0.52 0.443 0.24 0.6192 0.594 0.249 1.42 -0.856 0.482 0.0756 1.121 0.425 0.165 1.09 -1.07 0.526 0.0413 1.384 0.342 0.122 0.958 PRS_PLINK_0.0199526231496888 TRUE 384 Other disorders of tympanic membrane Both 151 1483 7 sense organs darkseagreen4 1483, 151 371, 45 371, 38 370, 37 371, 31 -0.0694 0.0853 0.416 0.3809 0.933 0.789 1.1 -0.197 0.23 0.394 0.405 0.822 0.523 1.29 -0.214 0.234 0.36 0.4432 0.807 0.51 1.28 -0.273 0.252 0.278 0.5565 0.761 0.465 1.25 PRS_PLINK_0.0199526231496888 FALSE 384.1 Myringitis Both 15 144 7 sense organs darkseagreen4 144, 15 36, 3 36, 7 36, 2 36, 3 -0.47 0.321 0.143 0.8444 0.625 0.333 1.17 0.435 0.686 0.525 0.2795 1.55 0.403 5.92 -0.752 0.855 0.379 0.4209 0.472 0.0882 2.52 -0.324 0.941 0.73 0.1364 0.723 0.114 4.57 PRS_PLINK_0.0199526231496888 TRUE 384.4 Perforation of tympanic membrane Both 116 1146 7 sense organs darkseagreen4 1146, 116 287, 37 286, 26 286, 30 287, 23 -0.048 0.0981 0.625 0.2042 0.953 0.786 1.16 -0.331 0.265 0.212 0.6731 0.718 0.427 1.21 -0.228 0.259 0.378 0.4228 0.796 0.479 1.32 -0.346 0.289 0.23 0.6376 0.707 0.401 1.25 PRS_PLINK_0.0199526231496888 FALSE 385 Other disorders of middle ear and mastoid Both 109 1273 7 sense organs darkseagreen4 1273, 109 319, 26 318, 34 318, 20 318, 29 -0.0364 0.102 0.721 0.1424 0.964 0.79 1.18 0.227 0.269 0.397 0.4008 1.26 0.741 2.13 -0.295 0.306 0.335 0.4755 0.744 0.409 1.36 0.158 0.292 0.588 0.2303 1.17 0.661 2.08 PRS_PLINK_0.0199526231496888 FALSE 385.3 Cholesteatoma Both 75 848 7 sense organs darkseagreen4 848, 75 212, 19 212, 28 212, 11 212, 17 -0.116 0.122 0.34 0.469 0.89 0.702 1.13 0.318 0.308 0.301 0.521 1.37 0.752 2.51 -0.678 0.391 0.0829 1.081 0.507 0.236 1.09 -0.185 0.356 0.603 0.2193 0.831 0.414 1.67 PRS_PLINK_0.0199526231496888 FALSE 385.5 Tympanosclerosis and middle ear disease related to otitis media Both 29 382 7 sense organs darkseagreen4 382, 29 96, 8 95, 5 95, 4 96, 12 0.0464 0.195 0.812 0.09047 1.05 0.715 1.53 -0.451 0.555 0.416 0.3814 0.637 0.215 1.89 -0.481 0.582 0.409 0.3888 0.618 0.198 1.93 0.408 0.481 0.397 0.4013 1.5 0.585 3.86 PRS_PLINK_0.0199526231496888 TRUE 386 Vertiginous syndromes and other disorders of vestibular system Both 441 4612 7 sense organs darkseagreen4 4612, 441 1153, 133 1153, 114 1153, 96 1153, 98 -0.0759 0.0514 0.14 0.8532 0.927 0.838 1.03 -0.15 0.134 0.265 0.5774 0.861 0.662 1.12 -0.33 0.142 0.0203 1.693 0.719 0.544 0.95 -0.222 0.146 0.126 0.8985 0.801 0.602 1.06 PRS_PLINK_0.0199526231496888 FALSE 386.1 Meniere's disease Both 83 794 7 sense organs darkseagreen4 794, 83 199, 21 198, 20 198, 19 199, 23 0.0204 0.116 0.86 0.06525 1.02 0.813 1.28 -0.0442 0.328 0.893 0.04924 0.957 0.503 1.82 -0.0933 0.335 0.781 0.1075 0.911 0.472 1.76 0.234 0.331 0.48 0.319 1.26 0.661 2.41 PRS_PLINK_0.0199526231496888 FALSE 386.2 Peripheral or central vertigo Both 362 3816 7 sense organs darkseagreen4 3816, 362 954, 112 954, 99 954, 73 954, 78 -0.102 0.0564 0.0707 1.151 0.903 0.809 1.01 -0.115 0.145 0.427 0.3694 0.891 0.67 1.18 -0.417 0.159 0.00871 2.06 0.659 0.482 0.9 -0.294 0.161 0.0673 1.172 0.745 0.544 1.02 PRS_PLINK_0.0199526231496888 FALSE 386.21 Central origin vertigo Both 276 2906 7 sense organs darkseagreen4 2906, 276 727, 85 726, 71 726, 51 727, 69 -0.0486 0.0646 0.452 0.3448 0.953 0.839 1.08 -0.174 0.168 0.301 0.5208 0.84 0.604 1.17 -0.493 0.186 0.00801 2.096 0.611 0.424 0.879 -0.115 0.177 0.514 0.289 0.891 0.63 1.26 PRS_PLINK_0.0199526231496888 FALSE 386.3 Labyrinthitis Both 340 3692 7 sense organs darkseagreen4 3692, 340 923, 104 923, 80 923, 69 923, 87 -0.0332 0.0588 0.573 0.2418 0.967 0.862 1.09 -0.259 0.155 0.0945 1.024 0.772 0.569 1.05 -0.401 0.163 0.0141 1.851 0.67 0.486 0.922 -0.0737 0.159 0.643 0.1915 0.929 0.68 1.27 PRS_PLINK_0.0199526231496888 FALSE 386.9 Dizziness and giddiness (Light-headedness and vertigo) Both 1934 10481 7 sense organs darkseagreen4 10481, 1934 2621, 491 2620, 505 2620, 461 2620, 476 -0.0161 0.0256 0.529 0.2764 0.984 0.936 1.03 0.0278 0.07 0.691 0.1605 1.03 0.896 1.18 -0.0637 0.0722 0.378 0.4224 0.938 0.814 1.08 0.022 0.074 0.766 0.116 1.02 0.884 1.18 PRS_PLINK_0.0199526231496888 FALSE 388 Other disorders of ear Both 277 2635 7 sense organs darkseagreen4 2635, 277 659, 86 659, 74 658, 56 659, 61 -0.15 0.0653 0.0213 1.671 0.86 0.757 0.978 -0.155 0.167 0.355 0.4499 0.857 0.617 1.19 -0.396 0.182 0.0294 1.531 0.673 0.471 0.961 -0.23 0.184 0.21 0.6773 0.794 0.554 1.14 PRS_PLINK_0.0199526231496888 FALSE 389 Hearing loss Both 1771 10840 7 sense organs darkseagreen4 10840, 1771 2710, 507 2710, 428 2710, 418 2710, 417 -0.0448 0.0267 0.0928 1.033 0.956 0.908 1.01 -0.139 0.0721 0.0532 1.274 0.87 0.755 1 -0.157 0.0735 0.0326 1.486 0.855 0.74 0.987 -0.0792 0.0759 0.297 0.5276 0.924 0.796 1.07 PRS_PLINK_0.0199526231496888 FALSE 389.1 Sensorineural hearing loss Both 832 7198 7 sense organs darkseagreen4 7198, 832 1800, 255 1799, 189 1799, 185 1800, 203 -0.0639 0.0378 0.0912 1.04 0.938 0.871 1.01 -0.291 0.102 0.00446 2.351 0.747 0.611 0.913 -0.3 0.104 0.00391 2.408 0.741 0.604 0.908 -0.144 0.105 0.17 0.7699 0.866 0.705 1.06 PRS_PLINK_0.0199526231496888 FALSE 389.2 Conductive hearing loss Both 260 2754 7 sense organs darkseagreen4 2754, 260 689, 76 688, 71 688, 57 689, 56 -0.105 0.0682 0.123 0.9096 0.9 0.788 1.03 -0.0872 0.174 0.616 0.2106 0.917 0.652 1.29 -0.308 0.186 0.0979 1.009 0.735 0.51 1.06 -0.269 0.194 0.166 0.7811 0.764 0.523 1.12 PRS_PLINK_0.0199526231496888 FALSE 389.3 Degenerative and vascular disorders of ear Both 33 365 7 sense organs darkseagreen4 365, 33 92, 8 91, 12 91, 7 91, 6 -0.117 0.201 0.56 0.2516 0.89 0.601 1.32 0.302 0.457 0.509 0.2932 1.35 0.552 3.32 -0.116 0.496 0.816 0.08839 0.891 0.337 2.36 -0.211 0.532 0.692 0.1602 0.81 0.285 2.3 PRS_PLINK_0.0199526231496888 TRUE 389.4 Tinnitus Both 555 5539 7 sense organs darkseagreen4 5539, 555 1385, 147 1385, 141 1384, 126 1385, 141 -0.0491 0.046 0.285 0.5451 0.952 0.87 1.04 -0.0452 0.124 0.715 0.1458 0.956 0.75 1.22 -0.139 0.13 0.282 0.5492 0.87 0.674 1.12 -0.0119 0.131 0.927 0.03276 0.988 0.765 1.28 PRS_PLINK_0.0199526231496888 FALSE 389.5 Disorders of acoustic nerve Both 34 333 7 sense organs darkseagreen4 333, 34 84, 7 83, 12 83, 8 83, 7 -0.133 0.176 0.45 0.3464 0.876 0.62 1.24 0.465 0.484 0.337 0.4724 1.59 0.616 4.11 0.3 0.518 0.562 0.2502 1.35 0.489 3.72 -0.065 0.533 0.903 0.04427 0.937 0.329 2.67 PRS_PLINK_0.0199526231496888 TRUE 394 Rheumatic disease of the heart valves Both 548 2534 8 circulatory system red 2534, 548 634, 106 633, 129 633, 136 634, 177 0.198 0.049 5.07e-05 4.295 1.22 1.11 1.34 0.196 0.144 0.175 0.7577 1.22 0.917 1.61 0.224 0.145 0.124 0.9056 1.25 0.94 1.66 0.477 0.142 0.000793 3.101 1.61 1.22 2.13 PRS_PLINK_0.0199526231496888 FALSE 394.1 Mitral valve stenosis and aortic valve stenosis Both 132 518 8 circulatory system red 518, 132 130, 21 129, 35 129, 33 130, 43 0.187 0.107 0.0821 1.086 1.21 0.976 1.49 0.459 0.309 0.138 0.8608 1.58 0.863 2.9 0.441 0.32 0.169 0.773 1.55 0.829 2.91 0.742 0.323 0.0215 1.668 2.1 1.12 3.95 PRS_PLINK_0.0199526231496888 FALSE 394.2 Mitral valve disease Both 175 814 8 circulatory system red 814, 175 204, 38 203, 43 203, 36 204, 58 0.147 0.0883 0.097 1.013 1.16 0.974 1.38 0.11 0.246 0.654 0.1842 1.12 0.69 1.81 -0.083 0.259 0.749 0.1256 0.92 0.554 1.53 0.344 0.248 0.165 0.7816 1.41 0.867 2.3 PRS_PLINK_0.0199526231496888 FALSE 394.3 Aortic valve disease Both 64 244 8 circulatory system red 244, 64 61, 9 61, 21 61, 21 61, 13 0.0924 0.146 0.526 0.2791 1.1 0.824 1.46 0.921 0.46 0.0453 1.344 2.51 1.02 6.19 0.896 0.45 0.0465 1.332 2.45 1.01 5.92 0.266 0.488 0.586 0.2318 1.3 0.501 3.4 PRS_PLINK_0.0199526231496888 FALSE 394.4 Acute rheumatic heart disease Both 21 122 8 circulatory system red 122, 21 31, 4 30, 6 30, 8 31, 3 0.154 0.223 0.489 0.3104 1.17 0.753 1.81 0.472 0.712 0.507 0.2949 1.6 0.397 6.47 0.893 0.693 0.198 0.7035 2.44 0.627 9.5 0.139 0.872 0.874 0.05872 1.15 0.208 6.34 PRS_PLINK_0.0199526231496888 TRUE 394.7 Disease of tricuspid valve Both 276 1080 8 circulatory system red 1080, 276 270, 56 270, 60 270, 55 270, 105 0.243 0.0725 0.000794 3.1 1.28 1.11 1.47 0.0973 0.207 0.638 0.1954 1.1 0.735 1.65 -0.0167 0.216 0.938 0.02759 0.983 0.644 1.5 0.577 0.197 0.00333 2.478 1.78 1.21 2.62 PRS_PLINK_0.0199526231496888 FALSE 395 Heart valve disorders Both 1225 6432 8 circulatory system red 6432, 1225 1608, 254 1608, 304 1608, 327 1608, 340 0.142 0.0327 1.35e-05 4.871 1.15 1.08 1.23 0.211 0.0937 0.0242 1.616 1.24 1.03 1.48 0.272 0.0935 0.00367 2.435 1.31 1.09 1.58 0.335 0.0965 0.000516 3.287 1.4 1.16 1.69 PRS_PLINK_0.0199526231496888 FALSE 395.1 Nonrheumatic mitral valve disorders Both 776 4373 8 circulatory system red 4373, 776 1094, 163 1093, 194 1093, 207 1093, 212 0.135 0.0407 0.000903 3.045 1.14 1.06 1.24 0.193 0.116 0.095 1.022 1.21 0.967 1.52 0.245 0.116 0.0347 1.46 1.28 1.02 1.6 0.322 0.12 0.00707 2.151 1.38 1.09 1.74 PRS_PLINK_0.0199526231496888 FALSE 395.2 Nonrheumatic aortic valve disorders Both 554 3063 8 circulatory system red 3063, 554 766, 106 766, 135 765, 147 766, 166 0.186 0.0484 0.000117 3.931 1.2 1.1 1.32 0.273 0.141 0.0537 1.27 1.31 0.996 1.73 0.345 0.14 0.0139 1.857 1.41 1.07 1.86 0.46 0.144 0.00137 2.862 1.58 1.2 2.1 PRS_PLINK_0.0199526231496888 FALSE 395.3 Nonrheumatic tricuspid valve disorders Both 237 918 8 circulatory system red 918, 237 230, 57 229, 48 229, 59 230, 73 0.13 0.0766 0.0908 1.042 1.14 0.98 1.32 -0.121 0.22 0.583 0.2344 0.886 0.576 1.36 0.0146 0.215 0.946 0.02425 1.01 0.666 1.55 0.193 0.213 0.365 0.4379 1.21 0.799 1.84 PRS_PLINK_0.0199526231496888 FALSE 395.4 Nonrheumatic pulmonary valve disorders Both 45 289 8 circulatory system red 289, 45 73, 11 72, 10 72, 12 72, 12 0.149 0.157 0.341 0.4669 1.16 0.854 1.58 0.251 0.52 0.628 0.2017 1.29 0.464 3.56 0.292 0.465 0.53 0.2759 1.34 0.538 3.33 0.373 0.522 0.475 0.3234 1.45 0.522 4.04 PRS_PLINK_0.0199526231496888 TRUE 395.6 Heart valve replaced Both 406 1826 8 circulatory system red 1826, 406 457, 80 456, 106 456, 111 457, 109 0.111 0.0572 0.052 1.284 1.12 0.999 1.25 0.312 0.164 0.0565 1.248 1.37 0.991 1.88 0.318 0.164 0.0525 1.28 1.37 0.997 1.89 0.335 0.173 0.0528 1.277 1.4 0.996 1.96 PRS_PLINK_0.0199526231496888 FALSE 396 Abnormal heart sounds Both 1245 9086 8 circulatory system red 9086, 1245 2271, 279 2271, 308 2271, 305 2272, 353 0.107 0.0313 0.000588 3.231 1.11 1.05 1.18 0.126 0.089 0.157 0.803 1.13 0.953 1.35 0.131 0.09 0.145 0.8397 1.14 0.956 1.36 0.312 0.091 0.000604 3.219 1.37 1.14 1.63 PRS_PLINK_0.0199526231496888 FALSE 401 Hypertension Both 3333 9450 8 circulatory system red 9450, 3333 2363, 647 2362, 794 2362, 873 2363, 1018 0.3 0.024 8.86e-36 35.05 1.35 1.29 1.41 0.301 0.0674 8.09e-06 5.092 1.35 1.18 1.54 0.468 0.0686 9.68e-12 11.01 1.6 1.4 1.83 0.788 0.0709 1.07e-28 27.97 2.2 1.91 2.53 PRS_PLINK_0.0199526231496888 FALSE 401.1 Essential hypertension Both 3266 9447 8 circulatory system red 9447, 3266 2362, 631 2362, 774 2361, 852 2362, 1008 0.307 0.0242 7.51e-37 36.12 1.36 1.3 1.42 0.3 0.068 1.01e-05 4.994 1.35 1.18 1.54 0.47 0.0693 1.18e-11 10.93 1.6 1.4 1.83 0.811 0.0715 7.61e-30 29.12 2.25 1.96 2.59 PRS_PLINK_0.0199526231496888 FALSE 401.2 Hypertensive heart and/or renal disease Both 728 4936 8 circulatory system red 4936, 728 1234, 120 1234, 148 1234, 192 1234, 267 0.449 0.045 1.68e-23 22.78 1.57 1.43 1.71 0.323 0.136 0.0173 1.762 1.38 1.06 1.8 0.592 0.133 8.39e-06 5.076 1.81 1.39 2.35 1.17 0.136 7.79e-18 17.11 3.21 2.46 4.18 PRS_PLINK_0.0199526231496888 FALSE 401.21 Hypertensive heart disease Both 261 1891 8 circulatory system red 1891, 261 473, 33 473, 59 472, 61 473, 107 0.474 0.0721 5.07e-11 10.3 1.61 1.39 1.85 0.642 0.227 0.00469 2.329 1.9 1.22 2.97 0.703 0.227 0.00197 2.705 2.02 1.29 3.15 1.33 0.219 1.31e-09 8.883 3.78 2.46 5.82 PRS_PLINK_0.0199526231496888 FALSE 401.22 Hypertensive chronic kidney disease Both 441 4290 8 circulatory system red 4290, 441 1073, 75 1072, 77 1072, 116 1073, 173 0.48 0.055 2.71e-18 17.57 1.62 1.45 1.8 0.131 0.171 0.446 0.3506 1.14 0.815 1.59 0.542 0.161 0.000759 3.12 1.72 1.25 2.36 1.18 0.161 2.49e-13 12.6 3.25 2.37 4.45 PRS_PLINK_0.0199526231496888 FALSE 401.3 Other hypertensive complications Both 281 5602 8 circulatory system red 5602, 281 1401, 54 1400, 69 1400, 64 1401, 94 0.248 0.064 0.000105 3.977 1.28 1.13 1.45 0.277 0.184 0.133 0.8773 1.32 0.919 1.89 0.23 0.192 0.232 0.6354 1.26 0.864 1.83 0.725 0.185 8.61e-05 4.065 2.06 1.44 2.96 PRS_PLINK_0.0199526231496888 FALSE 411 Ischemic Heart Disease Both 1982 7317 8 circulatory system red 7317, 1982 1830, 445 1829, 481 1829, 514 1829, 541 0.14 0.0283 7.7e-07 6.113 1.15 1.09 1.22 0.126 0.0793 0.113 0.9481 1.13 0.971 1.32 0.197 0.0801 0.0138 1.861 1.22 1.04 1.43 0.32 0.082 9.75e-05 4.011 1.38 1.17 1.62 PRS_PLINK_0.0199526231496888 FALSE 411.1 Unstable angina (intermediate coronary syndrome) Both 196 1391 8 circulatory system red 1391, 196 348, 35 348, 46 347, 55 348, 59 0.218 0.0804 0.00678 2.169 1.24 1.06 1.46 0.306 0.238 0.2 0.6992 1.36 0.851 2.17 0.399 0.232 0.0861 1.065 1.49 0.945 2.35 0.775 0.247 0.00174 2.759 2.17 1.34 3.52 PRS_PLINK_0.0199526231496888 FALSE 411.2 Myocardial infarction Both 884 4243 8 circulatory system red 4243, 884 1061, 175 1061, 207 1060, 213 1061, 288 0.207 0.0397 1.76e-07 6.755 1.23 1.14 1.33 0.183 0.115 0.11 0.958 1.2 0.959 1.5 0.224 0.115 0.0522 1.282 1.25 0.998 1.57 0.518 0.115 6.34e-06 5.198 1.68 1.34 2.1 PRS_PLINK_0.0199526231496888 FALSE 411.3 Angina pectoris Both 561 3460 8 circulatory system red 3460, 561 865, 113 865, 135 865, 143 865, 169 0.192 0.0477 5.61e-05 4.251 1.21 1.1 1.33 0.21 0.138 0.129 0.8878 1.23 0.94 1.62 0.244 0.138 0.078 1.108 1.28 0.973 1.67 0.5 0.139 0.000336 3.474 1.65 1.25 2.17 PRS_PLINK_0.0199526231496888 FALSE 411.4 Coronary atherosclerosis Both 1637 6123 8 circulatory system red 6123, 1637 1531, 348 1531, 387 1530, 428 1531, 473 0.181 0.0311 5.6e-09 8.252 1.2 1.13 1.27 0.129 0.0888 0.147 0.8321 1.14 0.956 1.35 0.266 0.0888 0.00274 2.562 1.3 1.1 1.55 0.422 0.0908 3.35e-06 5.475 1.53 1.28 1.82 PRS_PLINK_0.0199526231496888 FALSE 411.41 Aneurysm and dissection of heart Both 54 281 8 circulatory system red 281, 54 71, 6 70, 14 70, 17 70, 17 0.315 0.16 0.0491 1.309 1.37 1 1.88 0.913 0.519 0.0786 1.105 2.49 0.901 6.9 1.08 0.501 0.0313 1.505 2.94 1.1 7.87 1.14 0.566 0.0433 1.364 3.14 1.04 9.52 PRS_PLINK_0.0199526231496888 FALSE 411.8 Other chronic ischemic heart disease, unspecified Both 1412 5415 8 circulatory system red 5415, 1412 1354, 285 1354, 332 1353, 365 1354, 429 0.206 0.0331 4.58e-10 9.339 1.23 1.15 1.31 0.173 0.0957 0.0709 1.149 1.19 0.985 1.43 0.284 0.0956 0.00298 2.526 1.33 1.1 1.6 0.503 0.0969 2.16e-07 6.665 1.65 1.37 2 PRS_PLINK_0.0199526231496888 FALSE 411.9 Other acute and subacute forms of ischemic heart disease Both 133 692 8 circulatory system red 692, 133 173, 22 173, 32 173, 35 173, 44 0.281 0.0999 0.00487 2.313 1.32 1.09 1.61 0.341 0.294 0.246 0.6091 1.41 0.79 2.5 0.426 0.297 0.151 0.821 1.53 0.856 2.74 0.678 0.294 0.0213 1.671 1.97 1.11 3.51 PRS_PLINK_0.0199526231496888 FALSE 414 Other forms of chronic heart disease Both 1003 4669 8 circulatory system red 4669, 1003 1168, 218 1167, 216 1167, 261 1167, 307 0.185 0.0368 4.63e-07 6.335 1.2 1.12 1.29 0.0214 0.107 0.841 0.07502 1.02 0.828 1.26 0.198 0.104 0.0583 1.234 1.22 0.993 1.5 0.38 0.105 0.000296 3.528 1.46 1.19 1.8 PRS_PLINK_0.0199526231496888 FALSE 414.2 ASCVD Both 195 1164 8 circulatory system red 1164, 195 291, 49 291, 42 291, 47 291, 57 0.141 0.0803 0.0798 1.098 1.15 0.983 1.35 -0.0907 0.227 0.69 0.1614 0.913 0.585 1.43 0.01 0.223 0.964 0.01588 1.01 0.652 1.56 0.112 0.221 0.614 0.212 1.12 0.725 1.73 PRS_PLINK_0.0199526231496888 FALSE 415 Pulmonary heart disease Both 1049 6666 8 circulatory system red 6666, 1049 1667, 229 1666, 246 1666, 298 1667, 275 0.117 0.0341 0.000588 3.23 1.12 1.05 1.2 0.101 0.0991 0.309 0.5107 1.11 0.911 1.34 0.27 0.0965 0.00517 2.287 1.31 1.08 1.58 0.229 0.101 0.0237 1.625 1.26 1.03 1.53 PRS_PLINK_0.0199526231496888 FALSE 415.1 Acute pulmonary heart disease Both 554 4156 8 circulatory system red 4156, 554 1039, 132 1039, 145 1039, 163 1039, 113 0.0146 0.0459 0.75 0.1248 1.01 0.927 1.11 0.109 0.129 0.396 0.4018 1.12 0.867 1.44 0.209 0.127 0.0991 1.004 1.23 0.961 1.58 -0.129 0.142 0.364 0.4386 0.879 0.666 1.16 PRS_PLINK_0.0199526231496888 FALSE 415.11 Pulmonary embolism and infarction, acute Both 551 4134 8 circulatory system red 4134, 551 1034, 131 1033, 145 1033, 163 1034, 111 0.0114 0.0461 0.804 0.0946 1.01 0.924 1.11 0.12 0.129 0.35 0.4553 1.13 0.876 1.45 0.219 0.127 0.0847 1.072 1.25 0.97 1.6 -0.136 0.143 0.342 0.4661 0.873 0.66 1.15 PRS_PLINK_0.0199526231496888 FALSE 415.2 Chronic pulmonary heart disease Both 615 3493 8 circulatory system red 3493, 615 874, 121 873, 141 873, 159 873, 194 0.202 0.045 6.75e-06 5.171 1.22 1.12 1.34 0.183 0.134 0.17 0.7703 1.2 0.925 1.56 0.256 0.133 0.0537 1.27 1.29 0.996 1.68 0.495 0.132 0.000186 3.73 1.64 1.27 2.13 PRS_PLINK_0.0199526231496888 FALSE 415.21 Primary pulmonary hypertension Both 253 1385 8 circulatory system red 1385, 253 347, 47 346, 57 346, 65 346, 84 0.25 0.0702 0.000366 3.437 1.28 1.12 1.47 0.226 0.211 0.285 0.5457 1.25 0.829 1.9 0.323 0.211 0.126 0.8983 1.38 0.913 2.09 0.542 0.208 0.00905 2.043 1.72 1.14 2.59 PRS_PLINK_0.0199526231496888 FALSE 416 Cardiomegaly Both 339 2503 8 circulatory system red 2503, 339 626, 73 626, 79 625, 82 626, 105 0.167 0.0598 0.00528 2.277 1.18 1.05 1.33 0.0949 0.173 0.583 0.2345 1.1 0.784 1.54 0.0968 0.173 0.575 0.2404 1.1 0.785 1.55 0.34 0.168 0.043 1.366 1.4 1.01 1.95 PRS_PLINK_0.0199526231496888 FALSE 418 Nonspecific chest pain Both 3531 9246 8 circulatory system red 9246, 3531 2312, 883 2311, 887 2311, 887 2312, 873 0.0262 0.0207 0.205 0.6888 1.03 0.986 1.07 0.0231 0.0571 0.686 0.1637 1.02 0.915 1.14 0.0192 0.058 0.741 0.1304 1.02 0.91 1.14 0.0281 0.0598 0.639 0.1948 1.03 0.915 1.16 PRS_PLINK_0.0199526231496888 FALSE 418.1 Precordial pain Both 338 2870 8 circulatory system red 2870, 338 718, 71 717, 90 717, 91 718, 85 0.0695 0.0586 0.236 0.6276 1.07 0.956 1.2 0.244 0.167 0.144 0.842 1.28 0.92 1.77 0.32 0.168 0.0577 1.238 1.38 0.99 1.91 0.176 0.176 0.317 0.4996 1.19 0.845 1.68 PRS_PLINK_0.0199526231496888 FALSE 420 Carditis Both 569 3051 8 circulatory system red 3051, 569 763, 134 763, 130 762, 161 763, 143 0.0926 0.0468 0.0476 1.322 1.1 1 1.2 0.00215 0.135 0.987 0.005561 1 0.77 1.3 0.192 0.131 0.142 0.8479 1.21 0.938 1.56 0.107 0.138 0.437 0.3596 1.11 0.85 1.46 PRS_PLINK_0.0199526231496888 FALSE 420.1 Myocarditis Both 50 221 8 circulatory system red 221, 50 56, 11 55, 17 55, 11 55, 11 -0.0694 0.159 0.662 0.179 0.933 0.683 1.27 0.516 0.442 0.243 0.615 1.68 0.705 3.99 -0.0857 0.493 0.862 0.06452 0.918 0.35 2.41 -0.229 0.495 0.644 0.1912 0.796 0.302 2.1 PRS_PLINK_0.0199526231496888 TRUE 420.2 Pericarditis Both 312 1686 8 circulatory system red 1686, 312 422, 72 421, 83 421, 74 422, 82 0.0764 0.062 0.218 0.6625 1.08 0.956 1.22 0.182 0.177 0.304 0.5173 1.2 0.848 1.7 0.0291 0.182 0.873 0.05884 1.03 0.72 1.47 0.156 0.185 0.397 0.4016 1.17 0.814 1.68 PRS_PLINK_0.0199526231496888 FALSE 420.21 Acute pericarditis Both 69 398 8 circulatory system red 398, 69 100, 10 99, 22 99, 14 100, 23 0.122 0.13 0.351 0.4546 1.13 0.875 1.46 0.998 0.413 0.0157 1.804 2.71 1.21 6.1 0.34 0.43 0.43 0.3666 1.4 0.604 3.27 0.664 0.406 0.102 0.9924 1.94 0.877 4.31 PRS_PLINK_0.0199526231496888 FALSE 420.22 Chronic pericarditis Both 55 229 8 circulatory system red 229, 55 58, 7 57, 17 57, 8 57, 23 0.435 0.167 0.00915 2.039 1.55 1.11 2.14 1.07 0.495 0.0302 1.52 2.92 1.11 7.7 0.251 0.597 0.674 0.1714 1.29 0.399 4.14 0.99 0.489 0.0431 1.365 2.69 1.03 7.02 PRS_PLINK_0.0199526231496888 FALSE 420.3 Endocarditis Both 255 1351 8 circulatory system red 1351, 255 338, 54 338, 57 337, 79 338, 65 0.11 0.0698 0.116 0.9354 1.12 0.973 1.28 0.0859 0.206 0.677 0.1694 1.09 0.727 1.63 0.391 0.196 0.0463 1.335 1.48 1.01 2.17 0.224 0.211 0.288 0.5406 1.25 0.828 1.89 PRS_PLINK_0.0199526231496888 FALSE 425 Cardiomyopathy Both 825 3671 8 circulatory system red 3671, 825 918, 144 918, 205 917, 218 918, 257 0.229 0.0402 1.24e-08 7.906 1.26 1.16 1.36 0.349 0.119 0.00343 2.464 1.42 1.12 1.79 0.409 0.12 0.000649 3.188 1.51 1.19 1.9 0.621 0.121 2.66e-07 6.575 1.86 1.47 2.36 PRS_PLINK_0.0199526231496888 FALSE 425.1 Primary/intrinsic cardiomyopathies Both 793 3464 8 circulatory system red 3464, 793 866, 141 866, 199 866, 207 866, 245 0.222 0.041 6.07e-08 7.217 1.25 1.15 1.35 0.339 0.121 0.00517 2.286 1.4 1.11 1.78 0.368 0.122 0.00255 2.594 1.45 1.14 1.84 0.593 0.123 1.42e-06 5.849 1.81 1.42 2.3 PRS_PLINK_0.0199526231496888 FALSE 425.11 Hypertrophic obstructive cardiomyopathy Both 92 376 8 circulatory system red 376, 92 94, 16 94, 19 94, 25 94, 32 0.172 0.122 0.159 0.7989 1.19 0.935 1.51 -0.0582 0.392 0.882 0.05456 0.943 0.437 2.03 0.292 0.363 0.42 0.3766 1.34 0.658 2.73 0.663 0.378 0.08 1.097 1.94 0.924 4.07 PRS_PLINK_0.0199526231496888 FALSE 425.12 Other hypertrophic cardiomyopathy Both 70 419 8 circulatory system red 419, 70 105, 20 105, 14 104, 16 105, 20 -0.00537 0.137 0.969 0.01379 0.995 0.76 1.3 -0.414 0.386 0.284 0.5473 0.661 0.31 1.41 -0.237 0.371 0.523 0.2817 0.789 0.381 1.63 0.0522 0.362 0.886 0.05281 1.05 0.518 2.14 PRS_PLINK_0.0199526231496888 FALSE 425.2 Secondary/extrinsic cardiomyopathies Both 167 648 8 circulatory system red 648, 167 162, 32 162, 38 162, 40 162, 57 0.252 0.0885 0.00435 2.361 1.29 1.08 1.53 0.175 0.273 0.522 0.2822 1.19 0.697 2.04 0.228 0.265 0.39 0.4094 1.26 0.748 2.11 0.642 0.256 0.0123 1.909 1.9 1.15 3.14 PRS_PLINK_0.0199526231496888 FALSE 425.8 Other cardiomyopathy Both 37 189 8 circulatory system red 189, 37 48, 3 47, 7 47, 9 47, 18 0.567 0.204 0.00539 2.268 1.76 1.18 2.63 0.871 0.744 0.242 0.6168 2.39 0.556 10.3 1.11 0.664 0.0934 1.03 3.05 0.829 11.2 1.37 0.624 0.0283 1.549 3.93 1.16 13.3 PRS_PLINK_0.0199526231496888 TRUE 426 Cardiac conduction disorders Both 3131 7038 8 circulatory system red 7038, 3131 1760, 773 1759, 795 1759, 796 1760, 766 0.0786 0.0244 0.00129 2.888 1.08 1.03 1.13 0.0886 0.0672 0.187 0.7274 1.09 0.958 1.25 0.0811 0.0682 0.234 0.6304 1.08 0.949 1.24 0.142 0.0711 0.0453 1.344 1.15 1 1.33 PRS_PLINK_0.0199526231496888 FALSE 426.2 Atrioventricular [AV] block Both 539 1970 8 circulatory system red 1970, 539 493, 114 492, 122 492, 134 493, 169 0.168 0.0526 0.00145 2.839 1.18 1.07 1.31 0.148 0.154 0.336 0.4734 1.16 0.858 1.57 0.177 0.152 0.244 0.6126 1.19 0.886 1.61 0.486 0.152 0.00139 2.857 1.63 1.21 2.19 PRS_PLINK_0.0199526231496888 FALSE 426.21 First degree AV block Both 343 1377 8 circulatory system red 1377, 343 345, 79 344, 74 344, 83 344, 107 0.146 0.064 0.0224 1.649 1.16 1.02 1.31 0.0414 0.186 0.824 0.08409 1.04 0.724 1.5 0.0688 0.182 0.706 0.1515 1.07 0.75 1.53 0.388 0.185 0.0364 1.438 1.47 1.02 2.12 PRS_PLINK_0.0199526231496888 FALSE 426.22 Mobitz II AV block Both 12 76 8 circulatory system red 76, 12 19, 1 19, 1 19, 2 19, 8 0.655 0.386 0.0896 1.048 1.93 0.904 4.1 -2.14 1.57 0.174 0.7605 0.118 0.00542 2.56 -0.498 1.17 0.67 0.1736 0.608 0.0612 6.03 1.04 0.957 0.277 0.557 2.83 0.434 18.4 PRS_PLINK_0.0199526231496888 TRUE 426.23 Second degree AV block Both 46 252 8 circulatory system red 252, 46 63, 6 63, 18 63, 9 63, 13 0.125 0.168 0.455 0.3417 1.13 0.816 1.58 1.01 0.499 0.0434 1.362 2.74 1.03 7.29 0.468 0.558 0.401 0.3964 1.6 0.535 4.77 0.888 0.572 0.121 0.9183 2.43 0.792 7.46 PRS_PLINK_0.0199526231496888 TRUE 426.24 Atrioventricular block, complete Both 173 558 8 circulatory system red 558, 173 140, 25 139, 38 139, 53 140, 57 0.295 0.0962 0.00215 2.668 1.34 1.11 1.62 0.639 0.299 0.0328 1.484 1.9 1.05 3.41 0.703 0.285 0.0137 1.864 2.02 1.16 3.53 0.874 0.287 0.00235 2.629 2.4 1.36 4.21 PRS_PLINK_0.0199526231496888 FALSE 426.25 Other heart block Both 54 261 8 circulatory system red 261, 54 66, 12 65, 13 65, 12 65, 17 0.148 0.16 0.354 0.4516 1.16 0.848 1.59 0.0556 0.459 0.904 0.04403 1.06 0.43 2.6 0.00049 0.437 0.999 0.0003884 1 0.425 2.36 0.558 0.447 0.212 0.6743 1.75 0.728 4.19 PRS_PLINK_0.0199526231496888 FALSE 426.3 Bundle branch block Both 623 2523 8 circulatory system red 2523, 623 631, 133 631, 141 630, 148 631, 201 0.208 0.0475 1.18e-05 4.93 1.23 1.12 1.35 0.133 0.14 0.343 0.4651 1.14 0.868 1.5 0.135 0.139 0.332 0.4794 1.15 0.871 1.5 0.48 0.137 0.000472 3.326 1.62 1.23 2.11 PRS_PLINK_0.0199526231496888 FALSE 426.31 Right bundle branch block Both 368 1780 8 circulatory system red 1780, 368 445, 84 445, 82 445, 84 445, 118 0.174 0.0594 0.00345 2.462 1.19 1.06 1.34 0.0385 0.173 0.824 0.08422 1.04 0.741 1.46 -0.0302 0.173 0.861 0.06479 0.97 0.691 1.36 0.372 0.167 0.026 1.585 1.45 1.05 2.01 PRS_PLINK_0.0199526231496888 FALSE 426.32 Left bundle branch block Both 289 1232 8 circulatory system red 1232, 289 308, 58 308, 70 308, 73 308, 88 0.244 0.069 0.000411 3.386 1.28 1.11 1.46 0.269 0.202 0.181 0.7413 1.31 0.882 1.94 0.246 0.199 0.215 0.6679 1.28 0.867 1.89 0.542 0.204 0.00791 2.102 1.72 1.15 2.56 PRS_PLINK_0.0199526231496888 FALSE 426.4 Anomalous atrioventricular excitation Both 31 234 8 circulatory system red 234, 31 59, 7 58, 12 58, 5 59, 7 -0.182 0.182 0.318 0.4975 0.834 0.583 1.19 0.678 0.501 0.176 0.7549 1.97 0.738 5.26 0.113 0.627 0.857 0.06682 1.12 0.327 3.83 -0.281 0.632 0.656 0.1832 0.755 0.219 2.6 PRS_PLINK_0.0199526231496888 TRUE 426.7 Abnormal electrocardiogram [ECG] [EKG] Both 2706 6959 8 circulatory system red 6959, 2706 1740, 671 1740, 674 1739, 691 1740, 669 0.0872 0.0255 0.000631 3.2 1.09 1.04 1.15 0.0558 0.0702 0.427 0.3696 1.06 0.921 1.21 0.0775 0.0709 0.274 0.5618 1.08 0.94 1.24 0.146 0.074 0.0479 1.319 1.16 1 1.34 PRS_PLINK_0.0199526231496888 FALSE 426.8 Other cardiac conduction disorders Both 188 1371 8 circulatory system red 1371, 188 343, 41 343, 44 342, 47 343, 56 0.202 0.0798 0.0115 1.941 1.22 1.05 1.43 0.072 0.231 0.755 0.1221 1.07 0.684 1.69 0.0932 0.23 0.685 0.1644 1.1 0.7 1.72 0.387 0.232 0.0948 1.023 1.47 0.935 2.32 PRS_PLINK_0.0199526231496888 FALSE 426.9 Cardiac pacemaker/device in situ Both 648 1978 8 circulatory system red 1978, 648 495, 114 494, 156 494, 164 495, 214 0.27 0.0486 2.91e-08 7.536 1.31 1.19 1.44 0.38 0.146 0.00906 2.043 1.46 1.1 1.95 0.416 0.146 0.00422 2.375 1.52 1.14 2.02 0.791 0.146 5.83e-08 7.234 2.21 1.66 2.94 PRS_PLINK_0.0199526231496888 FALSE 426.91 Cardiac pacemaker in situ Both 398 1259 8 circulatory system red 1259, 398 315, 74 315, 82 314, 105 315, 137 0.276 0.061 5.91e-06 5.229 1.32 1.17 1.49 0.204 0.187 0.275 0.5602 1.23 0.85 1.77 0.376 0.18 0.0366 1.436 1.46 1.02 2.07 0.747 0.18 3.49e-05 4.458 2.11 1.48 3.01 PRS_PLINK_0.0199526231496888 FALSE 426.92 Cardiac defibrillator in situ Both 417 1107 8 circulatory system red 1107, 417 277, 64 277, 95 276, 108 277, 150 0.311 0.0611 3.57e-07 6.448 1.36 1.21 1.54 0.454 0.19 0.0167 1.777 1.57 1.09 2.28 0.556 0.185 0.00266 2.575 1.74 1.21 2.51 0.942 0.185 3.52e-07 6.453 2.57 1.79 3.69 PRS_PLINK_0.0199526231496888 FALSE 427 Cardiac dysrhythmias Both 4923 7159 8 circulatory system red 7159, 4923 1790, 1237 1790, 1212 1789, 1264 1790, 1209 0.0552 0.0201 0.00589 2.23 1.06 1.02 1.1 0.0257 0.0553 0.643 0.1921 1.03 0.921 1.14 0.0728 0.0559 0.193 0.7149 1.08 0.964 1.2 0.0878 0.0581 0.131 0.8837 1.09 0.974 1.22 PRS_PLINK_0.0199526231496888 FALSE 427.1 Paroxysmal tachycardia, unspecified Both 929 4167 8 circulatory system red 4167, 929 1042, 214 1042, 223 1041, 245 1042, 247 0.0867 0.0384 0.0238 1.623 1.09 1.01 1.18 0.0688 0.11 0.53 0.2758 1.07 0.864 1.33 0.18 0.107 0.0933 1.03 1.2 0.97 1.48 0.219 0.112 0.0498 1.303 1.25 1 1.55 PRS_PLINK_0.0199526231496888 FALSE 427.11 Paroxysmal supraventricular tachycardia Both 583 3234 8 circulatory system red 3234, 583 809, 141 808, 141 808, 146 809, 155 0.0763 0.0467 0.102 0.991 1.08 0.985 1.18 0.0197 0.132 0.881 0.05497 1.02 0.788 1.32 0.0611 0.131 0.64 0.1935 1.06 0.823 1.37 0.146 0.134 0.275 0.56 1.16 0.89 1.5 PRS_PLINK_0.0199526231496888 FALSE 427.12 Paroxysmal ventricular tachycardia Both 487 1705 8 circulatory system red 1705, 487 427, 101 426, 113 426, 129 426, 144 0.134 0.054 0.0132 1.88 1.14 1.03 1.27 0.137 0.157 0.384 0.4155 1.15 0.843 1.56 0.233 0.154 0.129 0.8884 1.26 0.934 1.71 0.363 0.16 0.0229 1.64 1.44 1.05 1.97 PRS_PLINK_0.0199526231496888 FALSE 427.2 Atrial fibrillation and flutter Both 1570 3928 8 circulatory system red 3928, 1570 982, 364 982, 373 982, 411 982, 422 0.131 0.0342 0.000126 3.901 1.14 1.07 1.22 0.0734 0.0974 0.451 0.3462 1.08 0.889 1.3 0.177 0.096 0.0647 1.189 1.19 0.989 1.44 0.286 0.0998 0.00414 2.383 1.33 1.09 1.62 PRS_PLINK_0.0199526231496888 FALSE 427.21 Atrial fibrillation Both 1530 3832 8 circulatory system red 3832, 1530 958, 357 958, 370 958, 394 958, 409 0.122 0.0346 0.000434 3.362 1.13 1.06 1.21 0.0767 0.098 0.434 0.3625 1.08 0.891 1.31 0.152 0.0972 0.117 0.9314 1.16 0.963 1.41 0.269 0.101 0.00767 2.115 1.31 1.07 1.59 PRS_PLINK_0.0199526231496888 FALSE 427.22 Atrial flutter Both 604 1715 8 circulatory system red 1715, 604 429, 138 429, 146 428, 155 429, 165 0.108 0.05 0.0314 1.503 1.11 1.01 1.23 0.117 0.144 0.416 0.3805 1.12 0.847 1.49 0.149 0.142 0.293 0.5331 1.16 0.879 1.53 0.162 0.146 0.269 0.5701 1.18 0.882 1.57 PRS_PLINK_0.0199526231496888 FALSE 427.3 Other specified cardiac dysrhythmias Both 2463 7091 8 circulatory system red 7091, 2463 1773, 612 1773, 605 1772, 641 1773, 604 0.0681 0.0255 0.00756 2.122 1.07 1.02 1.13 0.0372 0.0704 0.597 0.2239 1.04 0.904 1.19 0.112 0.0706 0.112 0.952 1.12 0.974 1.28 0.115 0.074 0.119 0.9231 1.12 0.971 1.3 PRS_PLINK_0.0199526231496888 FALSE 427.4 Cardiac arrest and ventricular fibrillation Both 216 957 8 circulatory system red 957, 216 240, 37 239, 52 239, 62 239, 65 0.245 0.08 0.00224 2.649 1.28 1.09 1.49 0.462 0.243 0.0568 1.246 1.59 0.987 2.55 0.519 0.236 0.0278 1.557 1.68 1.06 2.67 0.59 0.239 0.0137 1.864 1.8 1.13 2.88 PRS_PLINK_0.0199526231496888 FALSE 427.41 Ventricular fibrillation and flutter Both 104 351 8 circulatory system red 351, 104 88, 14 88, 27 87, 39 88, 24 0.19 0.122 0.117 0.9319 1.21 0.953 1.54 0.869 0.409 0.0337 1.473 2.38 1.07 5.32 1.11 0.377 0.00314 2.503 3.04 1.45 6.37 0.533 0.401 0.184 0.7351 1.7 0.776 3.74 PRS_PLINK_0.0199526231496888 FALSE 427.42 Cardiac arrest Both 154 703 8 circulatory system red 703, 154 176, 26 176, 33 175, 41 176, 54 0.3 0.0935 0.00136 2.868 1.35 1.12 1.62 0.401 0.291 0.168 0.7751 1.49 0.845 2.64 0.429 0.281 0.127 0.8971 1.54 0.885 2.66 0.784 0.275 0.00442 2.355 2.19 1.28 3.76 PRS_PLINK_0.0199526231496888 FALSE 427.5 Arrhythmia (cardiac) NOS Both 2065 7056 8 circulatory system red 7056, 2065 1764, 502 1764, 503 1764, 528 1764, 531 0.0688 0.0271 0.0113 1.947 1.07 1.02 1.13 0.0221 0.0759 0.771 0.1131 1.02 0.881 1.19 0.0896 0.0761 0.239 0.6217 1.09 0.942 1.27 0.153 0.0784 0.0508 1.294 1.17 0.999 1.36 PRS_PLINK_0.0199526231496888 FALSE 427.6 Premature beats Both 671 3420 8 circulatory system red 3420, 671 855, 158 855, 148 855, 178 855, 187 0.136 0.0448 0.00234 2.632 1.15 1.05 1.25 -0.0114 0.128 0.929 0.03191 0.989 0.77 1.27 0.172 0.125 0.167 0.7776 1.19 0.931 1.52 0.271 0.128 0.0349 1.457 1.31 1.02 1.69 PRS_PLINK_0.0199526231496888 FALSE 427.61 Supraventricular premature beats Both 167 1065 8 circulatory system red 1065, 167 267, 40 266, 38 266, 38 266, 51 0.0775 0.0853 0.364 0.4393 1.08 0.914 1.28 0.0227 0.247 0.927 0.03308 1.02 0.63 1.66 -0.0837 0.245 0.732 0.1353 0.92 0.569 1.49 0.192 0.237 0.417 0.3799 1.21 0.762 1.93 PRS_PLINK_0.0199526231496888 FALSE 427.7 Tachycardia NOS Both 1730 7083 8 circulatory system red 7083, 1730 1771, 411 1771, 443 1770, 438 1771, 437 0.0685 0.0281 0.0147 1.833 1.07 1.01 1.13 0.11 0.0782 0.158 0.8008 1.12 0.958 1.3 0.0874 0.0794 0.271 0.5665 1.09 0.934 1.28 0.124 0.0822 0.132 0.8797 1.13 0.963 1.33 PRS_PLINK_0.0199526231496888 FALSE 427.8 Sinoatrial node dysfunction (Bradycardia) Both 232 1218 8 circulatory system red 1218, 232 305, 49 304, 58 304, 58 305, 67 0.138 0.0751 0.0654 1.184 1.15 0.991 1.33 0.24 0.215 0.266 0.5746 1.27 0.833 1.94 0.254 0.217 0.241 0.6176 1.29 0.843 1.97 0.385 0.216 0.0742 1.129 1.47 0.963 2.24 PRS_PLINK_0.0199526231496888 FALSE 427.9 Palpitations Both 1359 6852 8 circulatory system red 6852, 1359 1713, 366 1713, 336 1713, 329 1713, 328 0.0448 0.031 0.148 0.8304 1.05 0.984 1.11 -0.0455 0.0846 0.591 0.2286 0.956 0.81 1.13 -0.0456 0.0859 0.596 0.2248 0.955 0.807 1.13 0.0246 0.0886 0.781 0.1072 1.02 0.862 1.22 PRS_PLINK_0.0199526231496888 FALSE 428 Congestive heart failure; nonhypertensive Both 1351 5030 8 circulatory system red 5030, 1351 1258, 279 1257, 324 1257, 363 1258, 384 0.172 0.033 1.79e-07 6.747 1.19 1.11 1.27 0.214 0.0963 0.026 1.584 1.24 1.03 1.5 0.329 0.0954 0.000563 3.249 1.39 1.15 1.68 0.393 0.0986 6.73e-05 4.172 1.48 1.22 1.8 PRS_PLINK_0.0199526231496888 FALSE 428.1 Congestive heart failure (CHF) NOS Both 1228 4623 8 circulatory system red 4623, 1228 1156, 247 1156, 295 1155, 333 1156, 352 0.18 0.0344 1.67e-07 6.778 1.2 1.12 1.28 0.234 0.101 0.0199 1.701 1.26 1.04 1.54 0.343 0.0998 0.000598 3.224 1.41 1.16 1.71 0.415 0.103 5.41e-05 4.267 1.51 1.24 1.85 PRS_PLINK_0.0199526231496888 FALSE 428.2 Heart failure NOS Both 1174 4365 8 circulatory system red 4365, 1174 1092, 239 1091, 269 1091, 314 1091, 351 0.203 0.0354 1.02e-08 7.993 1.22 1.14 1.31 0.178 0.104 0.0875 1.058 1.19 0.974 1.47 0.325 0.102 0.00152 2.819 1.38 1.13 1.69 0.467 0.105 9.03e-06 5.044 1.59 1.3 1.96 PRS_PLINK_0.0199526231496888 FALSE 428.3 Heart failure with reduced EF [Systolic or combined heart failure] Both 748 2505 8 circulatory system red 2505, 748 627, 137 626, 177 626, 202 626, 231 0.251 0.0438 9.14e-09 8.039 1.29 1.18 1.4 0.301 0.131 0.0212 1.673 1.35 1.05 1.74 0.412 0.129 0.00142 2.847 1.51 1.17 1.94 0.592 0.132 7.1e-06 5.149 1.81 1.4 2.34 PRS_PLINK_0.0199526231496888 FALSE 428.4 Heart failure with preserved EF [Diastolic heart failure] Both 473 2335 8 circulatory system red 2335, 473 584, 91 584, 109 583, 115 584, 157 0.262 0.0529 7.21e-07 6.142 1.3 1.17 1.44 0.214 0.156 0.169 0.771 1.24 0.913 1.68 0.248 0.156 0.112 0.9496 1.28 0.944 1.74 0.613 0.154 7.3e-05 4.136 1.85 1.36 2.5 PRS_PLINK_0.0199526231496888 FALSE 429 Ill-defined descriptions and complications of heart disease Both 3412 8936 8 circulatory system red 8936, 3412 2234, 820 2234, 849 2234, 888 2234, 854 0.0887 0.0215 3.73e-05 4.429 1.09 1.05 1.14 0.0687 0.0597 0.25 0.6021 1.07 0.953 1.2 0.143 0.0602 0.0176 1.755 1.15 1.03 1.3 0.145 0.0626 0.0203 1.692 1.16 1.02 1.31 PRS_PLINK_0.0199526231496888 FALSE 429.1 Heart transplant/surgery Both 488 2112 8 circulatory system red 2112, 488 528, 97 528, 115 528, 141 528, 135 0.146 0.0526 0.00539 2.268 1.16 1.04 1.28 0.162 0.152 0.286 0.5429 1.18 0.873 1.59 0.355 0.149 0.0172 1.765 1.43 1.07 1.91 0.361 0.157 0.0211 1.676 1.44 1.06 1.95 PRS_PLINK_0.0199526231496888 FALSE 429.2 Abnormal function study of cardiovascular system Both 1562 7509 8 circulatory system red 7509, 1562 1878, 355 1877, 389 1877, 406 1877, 411 0.129 0.03 1.81e-05 4.741 1.14 1.07 1.21 0.136 0.0842 0.105 0.978 1.15 0.972 1.35 0.193 0.0849 0.0229 1.641 1.21 1.03 1.43 0.255 0.0879 0.00367 2.435 1.29 1.09 1.53 PRS_PLINK_0.0199526231496888 FALSE 429.3 Symptoms involving cardiovascular system Both 2782 8916 8 circulatory system red 8916, 2782 2229, 681 2229, 689 2229, 719 2229, 692 0.0832 0.023 0.000292 3.535 1.09 1.04 1.14 0.0526 0.0637 0.409 0.3888 1.05 0.93 1.19 0.122 0.0642 0.0582 1.235 1.13 0.996 1.28 0.12 0.0668 0.0729 1.137 1.13 0.989 1.28 PRS_PLINK_0.0199526231496888 FALSE 429.9 Cardiac complications, not elsewhere classified Both 246 1180 8 circulatory system red 1180, 246 295, 49 295, 57 295, 62 295, 78 0.195 0.0718 0.00648 2.189 1.22 1.06 1.4 0.193 0.212 0.362 0.4411 1.21 0.8 1.84 0.27 0.21 0.2 0.6986 1.31 0.867 1.98 0.531 0.213 0.0126 1.9 1.7 1.12 2.58 PRS_PLINK_0.0199526231496888 FALSE 430 Intracranial hemorrhage Both 175 1675 8 circulatory system red 1675, 175 419, 31 419, 42 418, 55 419, 47 0.158 0.0808 0.0511 1.292 1.17 0.999 1.37 0.314 0.244 0.197 0.7059 1.37 0.85 2.21 0.483 0.237 0.0415 1.382 1.62 1.02 2.58 0.352 0.252 0.163 0.7877 1.42 0.867 2.33 PRS_PLINK_0.0199526231496888 FALSE 430.1 Subarachnoid hemorrhage Both 56 583 8 circulatory system red 583, 56 146, 7 146, 9 145, 22 146, 18 0.317 0.142 0.0252 1.599 1.37 1.04 1.81 0.122 0.48 0.799 0.09749 1.13 0.441 2.9 0.932 0.435 0.0322 1.493 2.54 1.08 5.96 0.776 0.459 0.091 1.041 2.17 0.883 5.34 PRS_PLINK_0.0199526231496888 FALSE 430.2 Intracerebral hemorrhage Both 75 793 8 circulatory system red 793, 75 199, 15 198, 19 198, 20 198, 21 0.146 0.12 0.226 0.6466 1.16 0.914 1.46 0.291 0.35 0.406 0.3913 1.34 0.673 2.66 0.11 0.355 0.756 0.1215 1.12 0.557 2.24 0.265 0.36 0.462 0.3355 1.3 0.644 2.64 PRS_PLINK_0.0199526231496888 FALSE 430.3 Subdural hemorrhage Both 50 510 8 circulatory system red 510, 50 128, 4 127, 16 127, 16 128, 14 0.313 0.151 0.0375 1.427 1.37 1.02 1.84 1.46 0.546 0.00744 2.129 4.31 1.48 12.6 1.33 0.556 0.0164 1.785 3.79 1.28 11.3 1.26 0.558 0.024 1.62 3.52 1.18 10.5 PRS_PLINK_0.0199526231496888 TRUE 433 Cerebrovascular disease Both 1153 7832 8 circulatory system red 7832, 1153 1958, 243 1958, 266 1958, 303 1958, 340 0.158 0.0327 1.4e-06 5.854 1.17 1.1 1.25 0.13 0.0959 0.177 0.7523 1.14 0.943 1.37 0.242 0.0945 0.0103 1.985 1.27 1.06 1.53 0.387 0.0947 4.42e-05 4.355 1.47 1.22 1.77 PRS_PLINK_0.0199526231496888 FALSE 433.1 Occlusion and stenosis of precerebral arteries Both 352 3033 8 circulatory system red 3033, 352 759, 69 758, 80 758, 88 758, 115 0.192 0.0572 0.000773 3.112 1.21 1.08 1.36 0.174 0.171 0.309 0.5101 1.19 0.851 1.66 0.236 0.17 0.165 0.7822 1.27 0.907 1.77 0.482 0.166 0.00372 2.43 1.62 1.17 2.24 PRS_PLINK_0.0199526231496888 FALSE 433.11 Occlusion of cerebral arteries, with cerebral infarction Both 45 492 8 circulatory system red 492, 45 123, 9 123, 8 123, 13 123, 15 0.26 0.159 0.101 0.9944 1.3 0.95 1.77 -0.12 0.46 0.794 0.1003 0.887 0.36 2.18 0.362 0.429 0.398 0.3998 1.44 0.62 3.33 0.588 0.433 0.174 0.7594 1.8 0.771 4.21 PRS_PLINK_0.0199526231496888 TRUE 433.12 Cerebral atherosclerosis Both 14 139 8 circulatory system red 139, 14 35, 3 35, 0 34, 4 35, 7 0.624 0.316 0.0487 1.313 1.87 1 3.47 -1.77 1.22 0.147 0.8314 0.17 0.0156 1.87 0.211 0.764 0.782 0.1068 1.24 0.276 5.52 1.24 0.873 0.155 0.8097 3.46 0.625 19.1 PRS_PLINK_0.0199526231496888 TRUE 433.2 Occlusion of cerebral arteries Both 511 4658 8 circulatory system red 4658, 511 1165, 99 1164, 121 1164, 133 1165, 157 0.177 0.0474 0.000178 3.75 1.19 1.09 1.31 0.228 0.142 0.108 0.9669 1.26 0.951 1.66 0.31 0.141 0.0276 1.56 1.36 1.03 1.8 0.478 0.142 0.000741 3.13 1.61 1.22 2.13 PRS_PLINK_0.0199526231496888 FALSE 433.21 Cerebral artery occlusion, with cerebral infarction Both 485 4492 8 circulatory system red 4492, 485 1123, 92 1123, 118 1123, 123 1123, 151 0.18 0.0484 0.000202 3.695 1.2 1.09 1.32 0.27 0.145 0.0626 1.204 1.31 0.986 1.74 0.293 0.146 0.0445 1.351 1.34 1.01 1.78 0.497 0.145 0.000632 3.199 1.64 1.24 2.18 PRS_PLINK_0.0199526231496888 FALSE 433.3 Cerebral ischemia Both 553 4840 8 circulatory system red 4840, 553 1210, 117 1210, 119 1210, 151 1210, 165 0.127 0.0456 0.00523 2.282 1.14 1.04 1.24 0.0392 0.136 0.774 0.1115 1.04 0.796 1.36 0.257 0.131 0.0505 1.297 1.29 0.999 1.67 0.356 0.133 0.00736 2.133 1.43 1.1 1.85 PRS_PLINK_0.0199526231496888 FALSE 433.31 Transient cerebral ischemia Both 486 4350 8 circulatory system red 4350, 486 1088, 101 1087, 108 1087, 131 1088, 145 0.139 0.0486 0.00413 2.384 1.15 1.05 1.26 0.0854 0.144 0.554 0.2563 1.09 0.821 1.45 0.257 0.141 0.0678 1.169 1.29 0.981 1.7 0.372 0.142 0.00877 2.057 1.45 1.1 1.92 PRS_PLINK_0.0199526231496888 FALSE 433.5 Cerebral aneurysm Both 109 1146 8 circulatory system red 1146, 109 287, 23 286, 27 286, 24 287, 35 0.144 0.102 0.16 0.7967 1.15 0.945 1.41 0.206 0.29 0.477 0.3215 1.23 0.696 2.17 0.0545 0.302 0.857 0.06704 1.06 0.584 1.91 0.425 0.291 0.145 0.8395 1.53 0.864 2.71 PRS_PLINK_0.0199526231496888 FALSE 433.6 Acute, but ill-defined cerebrovascular disease Both 99 872 8 circulatory system red 872, 99 218, 24 218, 23 218, 22 218, 30 0.0825 0.106 0.437 0.3597 1.09 0.882 1.34 -0.00352 0.302 0.991 0.004054 0.996 0.551 1.8 -0.192 0.311 0.538 0.2695 0.825 0.449 1.52 0.0843 0.305 0.782 0.1065 1.09 0.598 1.98 PRS_PLINK_0.0199526231496888 FALSE 433.8 Late effects of cerebrovascular disease Both 140 1436 8 circulatory system red 1436, 140 359, 22 359, 37 359, 34 359, 47 0.271 0.0878 0.00205 2.688 1.31 1.1 1.56 0.52 0.274 0.0575 1.24 1.68 0.984 2.87 0.428 0.28 0.126 0.8996 1.53 0.887 2.66 0.673 0.276 0.0147 1.834 1.96 1.14 3.37 PRS_PLINK_0.0199526231496888 FALSE 440 Atherosclerosis Both 511 3883 8 circulatory system red 3883, 511 971, 106 971, 117 970, 135 971, 153 0.167 0.0481 5e-04 3.301 1.18 1.08 1.3 0.12 0.142 0.399 0.3989 1.13 0.853 1.49 0.195 0.141 0.166 0.7787 1.21 0.922 1.6 0.456 0.144 0.00156 2.806 1.58 1.19 2.09 PRS_PLINK_0.0199526231496888 FALSE 440.1 Atherosclerosis of renal artery Both 21 412 8 circulatory system red 412, 21 103, 0 103, 4 103, 5 103, 12 0.678 0.212 0.00141 2.85 1.97 1.3 2.99 3.41 1.47 0.02 1.698 30.2 1.71 535 2.07 1.06 0.0503 1.299 7.94 0.998 63.2 3.13 1.25 0.0121 1.917 22.8 1.98 261 PRS_PLINK_0.0199526231496888 TRUE 440.2 Atherosclerosis of the extremities Both 306 2576 8 circulatory system red 2576, 306 644, 64 644, 65 644, 85 644, 92 0.155 0.0625 0.0129 1.888 1.17 1.03 1.32 0.0204 0.184 0.912 0.04013 1.02 0.712 1.46 0.205 0.179 0.251 0.6001 1.23 0.865 1.74 0.38 0.187 0.0414 1.383 1.46 1.01 2.11 PRS_PLINK_0.0199526231496888 FALSE 440.21 Atherosclerosis of native arteries of the extremities with ulceration or gangrene Both 51 456 8 circulatory system red 456, 51 114, 10 114, 9 114, 19 114, 13 0.134 0.148 0.364 0.439 1.14 0.856 1.53 0.00351 0.455 0.994 0.002679 1 0.411 2.45 0.497 0.434 0.252 0.5985 1.64 0.702 3.85 0.54 0.469 0.25 0.6025 1.72 0.684 4.31 PRS_PLINK_0.0199526231496888 FALSE 440.22 Atherosclerosis of native arteries of the extremities with intermittent claudication Both 208 1774 8 circulatory system red 1774, 208 444, 43 443, 46 443, 54 444, 65 0.0945 0.0763 0.216 0.6658 1.1 0.946 1.28 0.0344 0.22 0.876 0.05751 1.03 0.672 1.59 0.107 0.22 0.627 0.203 1.11 0.724 1.71 0.278 0.223 0.213 0.6715 1.32 0.852 2.05 PRS_PLINK_0.0199526231496888 FALSE 440.9 Atherosclerosis of aorta Both 188 1364 8 circulatory system red 1364, 188 341, 38 341, 44 341, 51 341, 55 0.121 0.0794 0.128 0.8931 1.13 0.966 1.32 0.171 0.236 0.468 0.3293 1.19 0.748 1.88 0.238 0.23 0.3 0.5222 1.27 0.808 1.99 0.362 0.237 0.127 0.8975 1.44 0.903 2.29 PRS_PLINK_0.0199526231496888 FALSE 441 Vascular insufficiency of intestine Both 159 1055 8 circulatory system red 1055, 159 264, 30 264, 39 263, 41 264, 49 0.175 0.0873 0.045 1.347 1.19 1 1.41 0.254 0.254 0.318 0.4978 1.29 0.783 2.12 0.315 0.257 0.22 0.6572 1.37 0.828 2.27 0.515 0.257 0.0452 1.345 1.67 1.01 2.77 PRS_PLINK_0.0199526231496888 FALSE 441.1 Acute vascular insufficiency of intestine Both 73 518 8 circulatory system red 518, 73 130, 7 129, 19 129, 24 130, 23 0.269 0.13 0.0377 1.424 1.31 1.02 1.69 0.892 0.431 0.0386 1.413 2.44 1.05 5.68 1.17 0.424 0.00567 2.247 3.23 1.41 7.41 0.924 0.437 0.0346 1.461 2.52 1.07 5.94 PRS_PLINK_0.0199526231496888 FALSE 441.2 Chronic vascular insufficiency of intestine Both 45 285 8 circulatory system red 285, 45 72, 6 71, 11 71, 14 71, 14 0.223 0.177 0.207 0.6844 1.25 0.884 1.77 0.591 0.513 0.249 0.6033 1.81 0.661 4.94 0.685 0.511 0.18 0.745 1.98 0.729 5.4 0.859 0.529 0.105 0.9802 2.36 0.836 6.66 PRS_PLINK_0.0199526231496888 TRUE 442 Other aneurysm Both 701 4398 8 circulatory system red 4398, 701 1100, 166 1099, 182 1099, 167 1100, 186 0.038 0.042 0.366 0.4369 1.04 0.957 1.13 0.0957 0.117 0.413 0.3846 1.1 0.875 1.38 0.0266 0.121 0.825 0.08349 1.03 0.811 1.3 0.171 0.122 0.162 0.7905 1.19 0.934 1.51 PRS_PLINK_0.0199526231496888 FALSE 442.1 Aortic aneurysm Both 530 3056 8 circulatory system red 3056, 530 764, 128 764, 136 764, 131 764, 135 0.00187 0.0485 0.969 0.01356 1 0.911 1.1 0.0467 0.134 0.728 0.1378 1.05 0.805 1.36 0.00935 0.138 0.946 0.0242 1.01 0.771 1.32 0.0477 0.141 0.736 0.1333 1.05 0.795 1.38 PRS_PLINK_0.0199526231496888 FALSE 442.11 Abdominal aortic aneurysm Both 283 1743 8 circulatory system red 1743, 283 436, 68 436, 81 435, 68 436, 66 -0.00998 0.067 0.882 0.0547 0.99 0.868 1.13 0.166 0.18 0.357 0.4478 1.18 0.829 1.68 -0.016 0.189 0.933 0.03027 0.984 0.68 1.43 0.0719 0.197 0.714 0.1461 1.07 0.731 1.58 PRS_PLINK_0.0199526231496888 FALSE 442.2 Aneurysm of iliac artery Both 38 319 8 circulatory system red 319, 38 80, 10 80, 8 79, 10 80, 10 0.0941 0.18 0.602 0.2208 1.1 0.772 1.56 -0.195 0.473 0.68 0.1678 0.823 0.326 2.08 0.00305 0.461 0.995 0.002298 1 0.406 2.48 -0.172 0.497 0.73 0.137 0.842 0.318 2.23 PRS_PLINK_0.0199526231496888 TRUE 442.3 Aneurysm of artery of lower extremity Both 46 328 8 circulatory system red 328, 46 82, 12 82, 15 82, 12 82, 7 -0.0643 0.174 0.712 0.1474 0.938 0.666 1.32 0.255 0.424 0.547 0.2623 1.29 0.563 2.96 -0.213 0.439 0.628 0.2022 0.808 0.342 1.91 -0.488 0.51 0.339 0.4703 0.614 0.226 1.67 PRS_PLINK_0.0199526231496888 TRUE 442.4 Arterial dissection Both 41 391 8 circulatory system red 391, 41 98, 7 98, 12 97, 12 98, 10 0.11 0.166 0.509 0.2937 1.12 0.806 1.54 0.491 0.477 0.303 0.5182 1.63 0.642 4.16 0.519 0.466 0.265 0.5763 1.68 0.674 4.19 0.432 0.495 0.383 0.4169 1.54 0.584 4.07 PRS_PLINK_0.0199526231496888 TRUE 442.8 Aneurysm of other specified artery Both 102 829 8 circulatory system red 829, 102 208, 23 207, 35 207, 19 207, 25 -0.0368 0.107 0.73 0.1366 0.964 0.782 1.19 0.397 0.281 0.158 0.8005 1.49 0.857 2.58 -0.179 0.322 0.579 0.2374 0.836 0.445 1.57 0.0925 0.319 0.772 0.1123 1.1 0.587 2.05 PRS_PLINK_0.0199526231496888 FALSE 443 Peripheral vascular disease Both 714 5668 8 circulatory system red 5668, 714 1417, 165 1417, 172 1417, 199 1417, 178 0.0461 0.0406 0.256 0.5923 1.05 0.967 1.13 0.0384 0.115 0.739 0.1312 1.04 0.829 1.3 0.154 0.114 0.177 0.7513 1.17 0.933 1.46 0.109 0.121 0.367 0.4351 1.12 0.88 1.41 PRS_PLINK_0.0199526231496888 FALSE 443.1 Raynaud's syndrome Both 268 2117 8 circulatory system red 2117, 268 530, 79 529, 68 529, 75 529, 46 -0.15 0.0673 0.0261 1.584 0.861 0.755 0.982 -0.133 0.176 0.449 0.3482 0.875 0.62 1.24 -0.0592 0.175 0.735 0.1339 0.942 0.669 1.33 -0.52 0.204 0.0106 1.973 0.595 0.399 0.886 PRS_PLINK_0.0199526231496888 FALSE 443.7 Peripheral angiopathy in diseases classified elsewhere Both 37 358 8 circulatory system red 358, 37 90, 10 89, 8 89, 7 90, 12 0.228 0.165 0.168 0.774 1.26 0.908 1.74 -0.083 0.479 0.863 0.06419 0.92 0.36 2.35 -0.285 0.5 0.57 0.2445 0.752 0.282 2.01 0.292 0.474 0.538 0.2696 1.34 0.529 3.39 PRS_PLINK_0.0199526231496888 TRUE 443.8 Other specified peripheral vascular diseases Both 582 4865 8 circulatory system red 4865, 582 1217, 131 1216, 137 1216, 162 1216, 152 0.0677 0.0446 0.129 0.89 1.07 0.981 1.17 0.0514 0.129 0.69 0.1613 1.05 0.818 1.35 0.185 0.126 0.143 0.845 1.2 0.939 1.54 0.218 0.133 0.1 0.9981 1.24 0.959 1.61 PRS_PLINK_0.0199526231496888 FALSE 443.9 Peripheral vascular disease, unspecified Both 454 3648 8 circulatory system red 3648, 454 912, 91 912, 100 912, 125 912, 138 0.14 0.051 0.00624 2.205 1.15 1.04 1.27 0.0774 0.153 0.613 0.2127 1.08 0.801 1.46 0.241 0.149 0.105 0.977 1.27 0.951 1.7 0.42 0.152 0.00565 2.248 1.52 1.13 2.05 PRS_PLINK_0.0199526231496888 FALSE 444 Arterial embolism and thrombosis Both 233 1764 8 circulatory system red 1764, 233 441, 45 441, 56 441, 78 441, 54 0.0784 0.0704 0.266 0.5759 1.08 0.942 1.24 0.216 0.211 0.306 0.5146 1.24 0.821 1.87 0.536 0.2 0.00749 2.126 1.71 1.15 2.53 0.22 0.221 0.317 0.4983 1.25 0.809 1.92 PRS_PLINK_0.0199526231496888 FALSE 444.1 Arterial embolism and thrombosis of lower extremity artery Both 78 572 8 circulatory system red 572, 78 143, 16 143, 17 143, 25 143, 20 0.113 0.121 0.35 0.4559 1.12 0.883 1.42 0.0657 0.361 0.856 0.06767 1.07 0.526 2.17 0.468 0.348 0.179 0.7465 1.6 0.807 3.16 0.251 0.359 0.485 0.3143 1.29 0.635 2.6 PRS_PLINK_0.0199526231496888 FALSE 444.2 Embolism and thrombosis of abdominal aorta Both 31 267 8 circulatory system red 267, 31 67, 5 67, 6 66, 8 67, 12 0.221 0.205 0.281 0.5513 1.25 0.834 1.87 0.29 0.616 0.638 0.195 1.34 0.399 4.47 0.227 0.576 0.694 0.1587 1.25 0.406 3.88 1.01 0.614 0.1 0.9985 2.74 0.823 9.13 PRS_PLINK_0.0199526231496888 TRUE 446 Polyarteritis nodosa and allied conditions Both 99 1051 8 circulatory system red 1051, 99 263, 23 263, 31 262, 25 263, 20 -0.0389 0.106 0.714 0.1464 0.962 0.781 1.18 0.263 0.282 0.35 0.4555 1.3 0.749 2.26 0.0517 0.3 0.863 0.06392 1.05 0.585 1.9 -0.187 0.317 0.556 0.2551 0.83 0.446 1.54 PRS_PLINK_0.0199526231496888 FALSE 446.4 Wegener's granulomatosis Both 24 272 8 circulatory system red 272, 24 68, 4 68, 13 68, 2 68, 5 0.0476 0.204 0.815 0.08869 1.05 0.704 1.56 1.04 0.546 0.0567 1.246 2.83 0.971 8.25 -0.363 0.748 0.627 0.2026 0.695 0.16 3.01 -0.0935 0.634 0.883 0.05417 0.911 0.263 3.16 PRS_PLINK_0.0199526231496888 TRUE 446.5 Giant cell arteritis Both 11 131 8 circulatory system red 131, 11 33, 5 33, 1 32, 4 33, 1 -0.352 0.296 0.235 0.6294 0.704 0.394 1.26 -0.919 0.872 0.292 0.5352 0.399 0.0722 2.2 -0.222 0.713 0.755 0.122 0.801 0.198 3.24 -1.06 0.924 0.25 0.6017 0.346 0.0565 2.11 PRS_PLINK_0.0199526231496888 TRUE 446.9 Arteritis NOS Both 67 685 8 circulatory system red 685, 67 172, 17 171, 16 171, 19 171, 15 0.0307 0.13 0.813 0.0897 1.03 0.799 1.33 -0.0486 0.357 0.892 0.04983 0.953 0.474 1.92 0.188 0.354 0.596 0.2251 1.21 0.603 2.42 0.144 0.382 0.706 0.151 1.15 0.547 2.44 PRS_PLINK_0.0199526231496888 FALSE 447 Other disorders of arteries and arterioles Both 608 4880 8 circulatory system red 4880, 608 1219, 138 1220, 156 1220, 156 1220, 158 0.0464 0.0437 0.288 0.541 1.05 0.962 1.14 0.13 0.124 0.292 0.5339 1.14 0.894 1.45 0.145 0.126 0.248 0.6057 1.16 0.904 1.48 0.174 0.13 0.182 0.7389 1.19 0.922 1.54 PRS_PLINK_0.0199526231496888 FALSE 447.1 Stricture of artery Both 122 1034 8 circulatory system red 1034, 122 259, 24 258, 32 258, 35 259, 31 0.0703 0.0959 0.463 0.3342 1.07 0.889 1.29 0.309 0.283 0.274 0.5617 1.36 0.783 2.37 0.437 0.286 0.127 0.8959 1.55 0.883 2.71 0.307 0.308 0.32 0.4955 1.36 0.743 2.49 PRS_PLINK_0.0199526231496888 FALSE 447.7 Aortic ectasia Both 197 1469 8 circulatory system red 1469, 197 368, 49 367, 60 367, 45 367, 43 -0.0743 0.0772 0.336 0.4735 0.928 0.798 1.08 0.23 0.206 0.265 0.5768 1.26 0.84 1.88 -0.0579 0.222 0.795 0.09986 0.944 0.61 1.46 -0.124 0.234 0.597 0.2237 0.884 0.558 1.4 PRS_PLINK_0.0199526231496888 FALSE 448 Disease of capillaries Both 310 2768 8 circulatory system red 2768, 310 692, 81 692, 75 692, 89 692, 65 -0.0748 0.062 0.228 0.6428 0.928 0.822 1.05 -0.11 0.169 0.515 0.2883 0.896 0.643 1.25 0.0323 0.166 0.845 0.07302 1.03 0.746 1.43 -0.245 0.184 0.183 0.7374 0.782 0.545 1.12 PRS_PLINK_0.0199526231496888 FALSE 450 Noninfectious disorders of lymphatic channels Both 550 5316 8 circulatory system red 5316, 550 1328, 140 1329, 140 1329, 132 1329, 138 -0.0169 0.0462 0.714 0.1464 0.983 0.898 1.08 -0.000829 0.126 0.995 0.002293 0.999 0.781 1.28 -0.0816 0.129 0.527 0.278 0.922 0.716 1.19 -0.0216 0.131 0.869 0.06096 0.979 0.757 1.27 PRS_PLINK_0.0199526231496888 FALSE 451 Phlebitis and thrombophlebitis Both 204 1832 8 circulatory system red 1832, 204 458, 52 458, 57 458, 42 458, 53 -0.0244 0.0748 0.745 0.128 0.976 0.843 1.13 0.0512 0.202 0.8 0.09681 1.05 0.708 1.56 -0.224 0.219 0.306 0.515 0.799 0.521 1.23 -0.0146 0.214 0.946 0.02429 0.986 0.648 1.5 PRS_PLINK_0.0199526231496888 FALSE 451.2 Phlebitis and thrombophlebitis of lower extremities Both 65 603 8 circulatory system red 603, 65 151, 17 151, 16 150, 12 151, 20 -0.0354 0.132 0.789 0.1028 0.965 0.745 1.25 -0.0271 0.355 0.939 0.02732 0.973 0.486 1.95 -0.323 0.39 0.408 0.3891 0.724 0.337 1.56 0.2 0.352 0.569 0.2449 1.22 0.613 2.44 PRS_PLINK_0.0199526231496888 FALSE 452 Other venous embolism and thrombosis Both 1407 7866 8 circulatory system red 7866, 1407 1967, 326 1966, 374 1966, 358 1967, 348 0.0788 0.0302 0.00906 2.043 1.08 1.02 1.15 0.164 0.0842 0.0508 1.294 1.18 0.999 1.39 0.119 0.0856 0.166 0.781 1.13 0.952 1.33 0.123 0.0887 0.166 0.7804 1.13 0.95 1.35 PRS_PLINK_0.0199526231496888 FALSE 452.1 Iatrogenic pulmonary embolism and infarction Both 86 640 8 circulatory system red 640, 86 160, 20 160, 19 160, 22 160, 25 0.105 0.119 0.376 0.425 1.11 0.88 1.4 -0.0956 0.34 0.779 0.1086 0.909 0.466 1.77 0.0863 0.324 0.79 0.1024 1.09 0.578 2.06 0.377 0.333 0.256 0.5912 1.46 0.76 2.8 PRS_PLINK_0.0199526231496888 FALSE 452.2 Deep vein thrombosis [DVT] Both 915 6607 8 circulatory system red 6607, 915 1652, 217 1652, 223 1651, 230 1652, 244 0.0864 0.0362 0.017 1.77 1.09 1.02 1.17 0.067 0.103 0.513 0.2895 1.07 0.875 1.31 0.0937 0.103 0.362 0.4408 1.1 0.898 1.34 0.147 0.105 0.16 0.796 1.16 0.944 1.42 PRS_PLINK_0.0199526231496888 FALSE 452.8 Postphlebitic syndrome Both 52 435 8 circulatory system red 435, 52 109, 20 109, 9 108, 10 109, 13 -0.188 0.142 0.186 0.7316 0.829 0.628 1.09 -0.772 0.41 0.0595 1.225 0.462 0.207 1.03 -0.677 0.405 0.0945 1.025 0.508 0.23 1.12 -0.481 0.379 0.204 0.6899 0.618 0.294 1.3 PRS_PLINK_0.0199526231496888 FALSE 453 Chronic venous hypertension Both 62 547 8 circulatory system red 547, 62 137, 20 137, 18 136, 12 137, 12 -0.222 0.134 0.0967 1.014 0.801 0.617 1.04 -0.109 0.343 0.752 0.124 0.897 0.458 1.76 -0.465 0.371 0.21 0.6788 0.628 0.303 1.3 -0.352 0.396 0.373 0.4284 0.703 0.324 1.53 PRS_PLINK_0.0199526231496888 FALSE 454 Varicose veins Both 789 6137 8 circulatory system red 6137, 789 1535, 210 1534, 207 1534, 181 1534, 191 -0.0188 0.0388 0.628 0.2018 0.981 0.909 1.06 0.00175 0.105 0.987 0.005821 1 0.816 1.23 -0.146 0.109 0.182 0.7388 0.864 0.697 1.07 -0.0856 0.111 0.442 0.3547 0.918 0.738 1.14 PRS_PLINK_0.0199526231496888 FALSE 454.1 Varicose veins of lower extremity Both 659 5393 8 circulatory system red 5393, 659 1349, 187 1348, 174 1348, 140 1348, 158 -0.0444 0.0424 0.295 0.5301 0.957 0.88 1.04 -0.0458 0.113 0.684 0.1649 0.955 0.766 1.19 -0.28 0.12 0.0197 1.706 0.756 0.597 0.956 -0.152 0.12 0.205 0.689 0.859 0.679 1.09 PRS_PLINK_0.0199526231496888 FALSE 454.11 Varicose veins of lower extremity, symptomtic Both 427 3647 8 circulatory system red 3647, 427 912, 118 912, 116 911, 91 912, 102 -0.0539 0.0522 0.302 0.5204 0.947 0.855 1.05 -0.0196 0.14 0.888 0.05138 0.981 0.746 1.29 -0.264 0.149 0.0762 1.118 0.768 0.574 1.03 -0.163 0.149 0.275 0.5602 0.85 0.634 1.14 PRS_PLINK_0.0199526231496888 FALSE 455 Hemorrhoids Both 1511 8038 8 circulatory system red 8038, 1511 2010, 421 2009, 396 2009, 352 2010, 342 -0.042 0.0293 0.152 0.8177 0.959 0.905 1.02 -0.0139 0.0784 0.859 0.06596 0.986 0.846 1.15 -0.133 0.0816 0.103 0.9878 0.875 0.746 1.03 -0.121 0.0849 0.154 0.8136 0.886 0.75 1.05 PRS_PLINK_0.0199526231496888 FALSE 456 Chronic venous insufficiency [CVI] Both 811 6416 8 circulatory system red 6416, 811 1604, 216 1604, 208 1604, 184 1604, 203 0.0227 0.0384 0.555 0.2555 1.02 0.949 1.1 -0.00851 0.104 0.935 0.02928 0.992 0.809 1.22 -0.114 0.108 0.292 0.5343 0.892 0.721 1.1 -0.0029 0.109 0.979 0.00928 0.997 0.805 1.24 PRS_PLINK_0.0199526231496888 FALSE 457 Encounter for long-term (current) use of anticoagulants, antithrombotics, aspirin Both 495 3022 8 circulatory system red 3022, 495 756, 107 755, 104 755, 134 756, 150 0.194 0.0503 0.000118 3.93 1.21 1.1 1.34 0.00288 0.148 0.984 0.006797 1 0.751 1.34 0.243 0.142 0.0869 1.061 1.28 0.965 1.68 0.372 0.144 0.00961 2.017 1.45 1.09 1.92 PRS_PLINK_0.0199526231496888 FALSE 457.2 Encounter for long-term (current) use of antiplatelets/antithrombotics Both 88 566 8 circulatory system red 566, 88 142, 9 141, 22 141, 21 142, 36 0.499 0.123 5.17e-05 4.286 1.65 1.29 2.1 0.82 0.393 0.0369 1.433 2.27 1.05 4.91 0.821 0.398 0.0393 1.405 2.27 1.04 4.96 1.34 0.388 0.000575 3.24 3.8 1.78 8.13 PRS_PLINK_0.0199526231496888 FALSE 457.3 Encounter for long-term (current) use of aspirin Both 462 2881 8 circulatory system red 2881, 462 721, 105 720, 95 720, 126 720, 136 0.178 0.0519 0.000608 3.216 1.19 1.08 1.32 -0.0601 0.152 0.692 0.1596 0.942 0.699 1.27 0.198 0.145 0.171 0.7663 1.22 0.918 1.62 0.299 0.147 0.0421 1.375 1.35 1.01 1.8 PRS_PLINK_0.0199526231496888 FALSE 458 Hypotension Both 2073 7935 8 circulatory system red 7935, 2073 1984, 497 1984, 520 1983, 526 1984, 529 0.0954 0.0262 0.000275 3.561 1.1 1.04 1.16 0.0979 0.0732 0.181 0.7414 1.1 0.955 1.27 0.105 0.074 0.158 0.8013 1.11 0.96 1.28 0.145 0.0765 0.0576 1.239 1.16 0.995 1.34 PRS_PLINK_0.0199526231496888 FALSE 458.1 Orthostatic hypotension Both 457 2715 8 circulatory system red 2715, 457 679, 121 679, 134 678, 95 679, 107 -0.0062 0.0521 0.905 0.04321 0.994 0.897 1.1 0.136 0.137 0.322 0.4915 1.15 0.875 1.5 -0.227 0.151 0.132 0.879 0.797 0.593 1.07 -0.0569 0.15 0.705 0.1518 0.945 0.704 1.27 PRS_PLINK_0.0199526231496888 FALSE 458.2 Iatrogenic hypotension Both 485 1984 8 circulatory system red 1984, 485 496, 96 496, 111 496, 143 496, 135 0.169 0.0536 0.00159 2.799 1.18 1.07 1.32 0.162 0.156 0.299 0.5242 1.18 0.866 1.6 0.388 0.151 0.0102 1.992 1.47 1.1 1.98 0.364 0.158 0.0214 1.671 1.44 1.06 1.96 PRS_PLINK_0.0199526231496888 FALSE 458.9 Hypotension NOS Both 1898 7492 8 circulatory system red 7492, 1898 1873, 448 1873, 484 1873, 473 1873, 492 0.0972 0.0272 0.000347 3.46 1.1 1.04 1.16 0.122 0.0759 0.109 0.9634 1.13 0.973 1.31 0.0949 0.0773 0.22 0.658 1.1 0.945 1.28 0.164 0.0792 0.0383 1.416 1.18 1.01 1.38 PRS_PLINK_0.0199526231496888 FALSE 459 Other disorders of circulatory system Both 2118 8977 8 circulatory system red 8977, 2118 2245, 487 2244, 526 2244, 568 2244, 536 0.0933 0.0258 0.000302 3.52 1.1 1.04 1.15 0.116 0.0729 0.112 0.952 1.12 0.973 1.3 0.208 0.0726 0.0041 2.387 1.23 1.07 1.42 0.173 0.0758 0.0223 1.651 1.19 1.02 1.38 PRS_PLINK_0.0199526231496888 FALSE 459.1 Hemorrhage NOS Both 251 1786 8 circulatory system red 1786, 251 447, 59 446, 67 446, 64 447, 61 0.0184 0.0702 0.793 0.1007 1.02 0.888 1.17 0.0881 0.191 0.644 0.1912 1.09 0.752 1.59 0.0473 0.196 0.809 0.09194 1.05 0.714 1.54 0.0358 0.205 0.862 0.06467 1.04 0.693 1.55 PRS_PLINK_0.0199526231496888 FALSE 459.7 Blood vessel replaced Both 383 2616 8 circulatory system red 2616, 383 654, 80 654, 116 654, 92 654, 95 0.0725 0.0562 0.197 0.7057 1.08 0.963 1.2 0.36 0.156 0.0211 1.676 1.43 1.06 1.94 0.129 0.166 0.437 0.3596 1.14 0.822 1.57 0.191 0.169 0.261 0.5838 1.21 0.868 1.69 PRS_PLINK_0.0199526231496888 FALSE 459.9 Circulatory disease NEC Both 1770 8474 8 circulatory system red 8474, 1770 2119, 405 2118, 437 2118, 484 2119, 443 0.102 0.028 0.000271 3.566 1.11 1.05 1.17 0.138 0.0792 0.0809 1.092 1.15 0.983 1.34 0.247 0.0784 0.00162 2.79 1.28 1.1 1.49 0.189 0.0824 0.0222 1.653 1.21 1.03 1.42 PRS_PLINK_0.0199526231496888 FALSE 464 Acute sinusitis Both 1406 8787 9 respiratory coral4 8787, 1406 2196, 364 2197, 367 2196, 321 2197, 354 -0.00805 0.0299 0.788 0.1035 0.992 0.935 1.05 -0.00407 0.0809 0.96 0.01776 0.996 0.85 1.17 -0.128 0.0845 0.128 0.8913 0.879 0.745 1.04 -0.00689 0.0849 0.935 0.02902 0.993 0.841 1.17 PRS_PLINK_0.0199526231496888 FALSE 465 Acute upper respiratory infections of multiple or unspecified sites Both 2998 9483 9 respiratory coral4 9483, 2998 2370, 793 2371, 770 2370, 731 2371, 704 -0.0429 0.022 0.0513 1.29 0.958 0.918 1 -0.0258 0.0596 0.665 0.177 0.975 0.867 1.1 -0.0916 0.0611 0.134 0.8728 0.912 0.809 1.03 -0.122 0.0635 0.0538 1.269 0.885 0.781 1 PRS_PLINK_0.0199526231496888 FALSE 465.2 Acute pharyngitis Both 1877 8896 9 respiratory coral4 8896, 1877 2223, 492 2224, 469 2224, 461 2224, 455 -0.0304 0.0267 0.254 0.5947 0.97 0.921 1.02 -0.0534 0.0727 0.463 0.3345 0.948 0.822 1.09 -0.087 0.0742 0.241 0.6185 0.917 0.793 1.06 -0.0997 0.0766 0.193 0.7136 0.905 0.779 1.05 PRS_PLINK_0.0199526231496888 FALSE 465.4 Acute laryngitis and tracheitis Both 121 1252 9 respiratory coral4 1252, 121 312, 34 313, 24 313, 32 313, 31 -0.00172 0.0953 0.986 0.006298 0.998 0.828 1.2 -0.323 0.271 0.234 0.63 0.724 0.425 1.23 -0.0847 0.258 0.743 0.1289 0.919 0.554 1.52 -0.0694 0.266 0.794 0.1 0.933 0.554 1.57 PRS_PLINK_0.0199526231496888 FALSE 470 Septal Deviations/Turbinate Hypertrophy Both 484 5009 9 respiratory coral4 5009, 484 1253, 142 1252, 117 1252, 114 1252, 111 -0.0913 0.0494 0.0646 1.189 0.913 0.829 1.01 -0.199 0.131 0.13 0.8862 0.82 0.634 1.06 -0.178 0.134 0.186 0.7298 0.837 0.643 1.09 -0.143 0.139 0.303 0.5186 0.867 0.66 1.14 PRS_PLINK_0.0199526231496888 FALSE 471 Nasal polyps Both 136 1536 9 respiratory coral4 1536, 136 384, 40 384, 41 384, 21 384, 34 -0.118 0.0926 0.201 0.6959 0.888 0.741 1.07 0.023 0.232 0.921 0.0357 1.02 0.649 1.61 -0.575 0.28 0.0401 1.397 0.563 0.325 0.974 -0.103 0.257 0.688 0.1626 0.902 0.545 1.49 PRS_PLINK_0.0199526231496888 FALSE 472 Chronic pharyngitis and nasopharyngitis Both 468 4723 9 respiratory coral4 4723, 468 1181, 130 1181, 125 1180, 115 1181, 98 -0.115 0.0506 0.0228 1.643 0.891 0.807 0.984 -0.0457 0.132 0.73 0.1368 0.955 0.737 1.24 -0.103 0.137 0.451 0.3455 0.902 0.69 1.18 -0.248 0.146 0.0896 1.048 0.781 0.587 1.04 PRS_PLINK_0.0199526231496888 FALSE 473 Diseases of the larynx and vocal cords Both 748 6607 9 respiratory coral4 6607, 748 1652, 203 1652, 188 1651, 181 1652, 176 -0.0385 0.0397 0.333 0.4778 0.962 0.89 1.04 -0.0587 0.107 0.584 0.2333 0.943 0.764 1.16 -0.107 0.11 0.329 0.4823 0.899 0.725 1.11 -0.121 0.113 0.284 0.5466 0.886 0.71 1.11 PRS_PLINK_0.0199526231496888 FALSE 473.1 Chronic laryngitis Both 18 199 9 respiratory coral4 199, 18 50, 2 50, 5 49, 5 50, 6 0.399 0.249 0.108 0.9647 1.49 0.916 2.43 0.494 0.732 0.5 0.3008 1.64 0.39 6.88 0.769 0.731 0.293 0.5338 2.16 0.515 9.04 1.49 0.886 0.0931 1.031 4.43 0.78 25.1 PRS_PLINK_0.0199526231496888 TRUE 473.3 Paralysis/spasm of vocal cords or larynx Both 170 1603 9 respiratory coral4 1603, 170 401, 40 401, 44 400, 39 401, 47 0.024 0.0815 0.768 0.1146 1.02 0.873 1.2 0.092 0.226 0.685 0.1646 1.1 0.703 1.71 0.000289 0.235 0.999 0.0004273 1 0.632 1.58 0.16 0.232 0.488 0.3112 1.17 0.746 1.85 PRS_PLINK_0.0199526231496888 FALSE 473.4 Voice disturbance Both 578 5528 9 respiratory coral4 5528, 578 1382, 161 1382, 138 1382, 138 1382, 141 -0.0245 0.0448 0.585 0.233 0.976 0.894 1.07 -0.138 0.122 0.258 0.5882 0.871 0.686 1.11 -0.157 0.123 0.205 0.6887 0.855 0.671 1.09 -0.118 0.126 0.349 0.4571 0.889 0.694 1.14 PRS_PLINK_0.0199526231496888 FALSE 474 Acute and chronic tonsillitis Both 339 2909 9 respiratory coral4 2909, 339 728, 92 727, 76 727, 86 727, 85 -0.0067 0.0607 0.912 0.03996 0.993 0.882 1.12 -0.175 0.164 0.287 0.542 0.84 0.609 1.16 -0.0986 0.163 0.546 0.2627 0.906 0.658 1.25 -0.0348 0.168 0.835 0.07806 0.966 0.695 1.34 PRS_PLINK_0.0199526231496888 FALSE 474.1 Acute tonsillitis Both 150 1371 9 respiratory coral4 1371, 150 343, 42 343, 37 342, 35 343, 36 -0.0779 0.0926 0.4 0.398 0.925 0.772 1.11 -0.176 0.239 0.461 0.3362 0.839 0.525 1.34 -0.21 0.249 0.398 0.4003 0.811 0.498 1.32 -0.166 0.255 0.515 0.288 0.847 0.513 1.4 PRS_PLINK_0.0199526231496888 FALSE 474.2 Chronic tonsillitis and adenoiditis Both 264 2422 9 respiratory coral4 2422, 264 606, 71 605, 61 605, 66 606, 66 -0.0113 0.068 0.868 0.06167 0.989 0.865 1.13 -0.148 0.183 0.421 0.3762 0.863 0.602 1.24 -0.0926 0.185 0.617 0.21 0.912 0.634 1.31 -0.0199 0.189 0.916 0.03801 0.98 0.677 1.42 PRS_PLINK_0.0199526231496888 FALSE 475 Chronic sinusitis Both 1190 7568 9 respiratory coral4 7568, 1190 1892, 322 1892, 320 1892, 272 1892, 276 -0.0704 0.0326 0.0307 1.513 0.932 0.874 0.993 -0.0104 0.0861 0.904 0.04371 0.99 0.836 1.17 -0.176 0.0907 0.0521 1.283 0.839 0.702 1 -0.152 0.0928 0.1 0.999 0.859 0.716 1.03 PRS_PLINK_0.0199526231496888 FALSE 475.9 Postnasal drip Both 256 2315 9 respiratory coral4 2315, 256 579, 76 579, 69 578, 50 579, 61 -0.105 0.068 0.123 0.9099 0.9 0.788 1.03 -0.122 0.176 0.49 0.3102 0.885 0.627 1.25 -0.423 0.195 0.0301 1.521 0.655 0.447 0.96 -0.239 0.189 0.206 0.6872 0.787 0.544 1.14 PRS_PLINK_0.0199526231496888 FALSE 476 Allergic rhinitis Both 3557 7637 9 respiratory coral4 7637, 3557 1910, 966 1909, 918 1909, 863 1909, 810 -0.0537 0.0213 0.0115 1.94 0.948 0.909 0.988 -0.0444 0.0572 0.437 0.3592 0.957 0.855 1.07 -0.092 0.0584 0.116 0.9374 0.912 0.813 1.02 -0.159 0.0611 0.00934 2.03 0.853 0.757 0.962 PRS_PLINK_0.0199526231496888 FALSE 477 Epistaxis or throat hemorrhage Both 325 2916 9 respiratory coral4 2916, 325 729, 69 729, 80 729, 91 729, 84 0.0807 0.0603 0.181 0.7435 1.08 0.963 1.22 0.147 0.173 0.395 0.4035 1.16 0.826 1.62 0.321 0.172 0.0618 1.209 1.38 0.984 1.93 0.241 0.182 0.185 0.7327 1.27 0.891 1.82 PRS_PLINK_0.0199526231496888 FALSE 478 Throat pain Both 121 1278 9 respiratory coral4 1278, 121 320, 33 319, 33 319, 22 320, 33 0.0345 0.0995 0.729 0.1372 1.04 0.852 1.26 0.044 0.258 0.865 0.0632 1.04 0.631 1.73 -0.224 0.289 0.438 0.3584 0.799 0.454 1.41 0.129 0.267 0.629 0.2013 1.14 0.674 1.92 PRS_PLINK_0.0199526231496888 FALSE 479 Other upper respiratory disease Both 1535 7615 9 respiratory coral4 7615, 1535 1904, 385 1904, 390 1903, 390 1904, 370 0.0225 0.0291 0.439 0.3577 1.02 0.966 1.08 0.0308 0.0794 0.698 0.1562 1.03 0.883 1.21 0.045 0.0808 0.577 0.2388 1.05 0.893 1.23 0.0223 0.0841 0.791 0.1018 1.02 0.867 1.21 PRS_PLINK_0.0199526231496888 FALSE 480 Pneumonia Both 1708 9924 9 respiratory coral4 9924, 1708 2481, 413 2481, 439 2481, 406 2481, 449 0.0498 0.0271 0.0662 1.179 1.05 0.997 1.11 0.0852 0.0753 0.258 0.5882 1.09 0.939 1.26 -0.00313 0.0775 0.968 0.0142 0.997 0.856 1.16 0.143 0.078 0.0663 1.178 1.15 0.99 1.34 PRS_PLINK_0.0199526231496888 FALSE 480.1 Bacterial pneumonia Both 377 2581 9 respiratory coral4 2581, 377 646, 83 645, 105 645, 92 645, 96 0.0763 0.057 0.181 0.7431 1.08 0.965 1.21 0.242 0.159 0.127 0.8957 1.27 0.933 1.74 0.118 0.164 0.471 0.327 1.13 0.816 1.55 0.234 0.17 0.167 0.7769 1.26 0.907 1.76 PRS_PLINK_0.0199526231496888 FALSE 480.11 Pneumococcal pneumonia Both 177 1286 9 respiratory coral4 1286, 177 322, 51 321, 42 321, 36 322, 47 0.0138 0.0839 0.869 0.06093 1.01 0.86 1.2 -0.177 0.223 0.427 0.3697 0.838 0.541 1.3 -0.382 0.235 0.104 0.9841 0.682 0.43 1.08 0.00586 0.229 0.98 0.008957 1.01 0.642 1.58 PRS_PLINK_0.0199526231496888 FALSE 480.12 Pseudomonal pneumonia Both 48 348 9 respiratory coral4 348, 48 87, 11 87, 15 87, 14 87, 8 -0.00744 0.156 0.962 0.01682 0.993 0.731 1.35 0.416 0.427 0.33 0.4816 1.52 0.656 3.5 0.273 0.433 0.529 0.2766 1.31 0.562 3.07 -0.242 0.483 0.616 0.2104 0.785 0.305 2.02 PRS_PLINK_0.0199526231496888 TRUE 480.13 MRSA pneumonia Both 41 275 9 respiratory coral4 275, 41 69, 12 69, 10 68, 8 69, 11 -0.0109 0.163 0.947 0.02376 0.989 0.719 1.36 -0.00855 0.476 0.986 0.006268 0.991 0.39 2.52 -0.404 0.505 0.424 0.3729 0.668 0.248 1.8 0.0206 0.48 0.966 0.01516 1.02 0.398 2.62 PRS_PLINK_0.0199526231496888 TRUE 480.2 Viral pneumonia Both 63 412 9 respiratory coral4 412, 63 103, 14 103, 19 103, 14 103, 16 0.117 0.134 0.383 0.4171 1.12 0.864 1.46 0.248 0.377 0.511 0.2912 1.28 0.612 2.68 0.148 0.402 0.713 0.1472 1.16 0.528 2.55 0.305 0.404 0.45 0.347 1.36 0.615 2.99 PRS_PLINK_0.0199526231496888 FALSE 480.3 Pneumonia due to fungus (mycoses) Both 55 359 9 respiratory coral4 359, 55 90, 16 90, 18 89, 13 90, 8 -0.18 0.151 0.234 0.6315 0.835 0.621 1.12 0.165 0.374 0.659 0.1808 1.18 0.567 2.45 -0.0604 0.405 0.881 0.05485 0.941 0.426 2.08 -0.304 0.464 0.512 0.291 0.738 0.297 1.83 PRS_PLINK_0.0199526231496888 FALSE 480.5 Bronchopneumonia and lung abscess Both 47 277 9 respiratory coral4 277, 47 70, 16 69, 10 69, 12 69, 9 -0.271 0.169 0.109 0.9628 0.763 0.548 1.06 -0.319 0.432 0.461 0.3362 0.727 0.311 1.7 -0.0614 0.44 0.889 0.05107 0.94 0.397 2.23 -0.27 0.497 0.587 0.2315 0.763 0.288 2.02 PRS_PLINK_0.0199526231496888 TRUE 481 Influenza Both 409 3766 9 respiratory coral4 3766, 409 942, 111 941, 99 941, 93 942, 105 -0.0416 0.0542 0.443 0.3538 0.959 0.863 1.07 -0.111 0.145 0.445 0.3517 0.895 0.673 1.19 -0.188 0.15 0.208 0.6811 0.828 0.618 1.11 -0.0874 0.149 0.557 0.2541 0.916 0.685 1.23 PRS_PLINK_0.0199526231496888 FALSE 483 Acute bronchitis and bronchiolitis Both 919 8093 9 respiratory coral4 8093, 919 2024, 236 2023, 237 2023, 219 2023, 227 -0.00432 0.0362 0.905 0.04337 0.996 0.927 1.07 0.0129 0.0978 0.895 0.04819 1.01 0.836 1.23 -0.0935 0.101 0.354 0.4516 0.911 0.747 1.11 -0.0571 0.103 0.579 0.2372 0.945 0.772 1.16 PRS_PLINK_0.0199526231496888 FALSE 495 Asthma Both 2513 9177 9 respiratory coral4 9177, 2513 2295, 617 2294, 609 2294, 597 2294, 689 0.0382 0.0234 0.102 0.9923 1.04 0.992 1.09 -0.0258 0.0651 0.692 0.1599 0.975 0.858 1.11 -0.0573 0.0661 0.386 0.4136 0.944 0.83 1.07 0.0916 0.0662 0.166 0.7794 1.1 0.963 1.25 PRS_PLINK_0.0199526231496888 FALSE 495.1 Chronic obstructive asthma Both 112 928 9 respiratory coral4 928, 112 232, 17 232, 32 232, 24 232, 39 0.204 0.103 0.0481 1.318 1.23 1 1.5 0.598 0.308 0.0522 1.282 1.82 0.994 3.33 0.331 0.327 0.311 0.5069 1.39 0.733 2.65 0.837 0.316 0.00807 2.093 2.31 1.24 4.29 PRS_PLINK_0.0199526231496888 FALSE 495.11 Chronic obstructive asthma with exacerbation Both 19 163 9 respiratory coral4 163, 19 41, 5 41, 4 40, 4 41, 6 -0.104 0.256 0.684 0.165 0.901 0.545 1.49 -0.0842 0.682 0.902 0.04493 0.919 0.242 3.5 -0.256 0.64 0.689 0.1615 0.774 0.221 2.72 -0.0501 0.666 0.94 0.02683 0.951 0.258 3.51 PRS_PLINK_0.0199526231496888 TRUE 495.2 Asthma with exacerbation Both 495 5259 9 respiratory coral4 5259, 495 1315, 123 1315, 130 1314, 107 1315, 135 0.0509 0.049 0.299 0.5247 1.05 0.956 1.16 0.0585 0.131 0.656 0.183 1.06 0.819 1.37 -0.122 0.14 0.384 0.4156 0.886 0.674 1.16 0.107 0.136 0.432 0.3643 1.11 0.852 1.45 PRS_PLINK_0.0199526231496888 FALSE 496 Chronic airway obstruction Both 1343 6955 9 respiratory coral4 6955, 1343 1739, 321 1739, 298 1738, 350 1739, 373 0.095 0.0309 0.00213 2.671 1.1 1.03 1.17 -0.0623 0.0891 0.484 0.3152 0.94 0.789 1.12 0.101 0.0877 0.251 0.6011 1.11 0.931 1.31 0.203 0.0886 0.0221 1.656 1.22 1.03 1.46 PRS_PLINK_0.0199526231496888 FALSE 496.1 Emphysema Both 547 3897 9 respiratory coral4 3897, 547 975, 126 974, 125 974, 139 974, 156 0.0707 0.0467 0.13 0.8865 1.07 0.979 1.18 0.00836 0.135 0.951 0.02204 1.01 0.774 1.31 0.109 0.133 0.414 0.3835 1.11 0.859 1.45 0.252 0.134 0.0606 1.218 1.29 0.989 1.67 PRS_PLINK_0.0199526231496888 FALSE 496.2 Chronic bronchitis Both 1019 6282 9 respiratory coral4 6282, 1019 1571, 247 1570, 210 1570, 261 1571, 301 0.115 0.0348 0.000945 3.024 1.12 1.05 1.2 -0.146 0.101 0.149 0.8269 0.864 0.708 1.05 0.055 0.0985 0.576 0.2395 1.06 0.871 1.28 0.218 0.0981 0.0266 1.575 1.24 1.03 1.51 PRS_PLINK_0.0199526231496888 FALSE 496.21 Obstructive chronic bronchitis Both 906 5754 9 respiratory coral4 5754, 906 1439, 222 1438, 183 1438, 225 1439, 276 0.128 0.0368 0.00049 3.31 1.14 1.06 1.22 -0.173 0.108 0.107 0.9688 0.841 0.681 1.04 0.0167 0.105 0.873 0.05903 1.02 0.828 1.25 0.237 0.103 0.0213 1.671 1.27 1.04 1.55 PRS_PLINK_0.0199526231496888 FALSE 496.3 Bronchiectasis Both 150 1140 9 respiratory coral4 1140, 150 285, 37 285, 31 285, 42 285, 40 0.0513 0.0874 0.557 0.2541 1.05 0.887 1.25 -0.205 0.255 0.421 0.3752 0.815 0.494 1.34 0.0653 0.244 0.789 0.1031 1.07 0.662 1.72 0.0406 0.246 0.869 0.06103 1.04 0.643 1.69 PRS_PLINK_0.0199526231496888 FALSE 497 Bronchitis Both 498 5079 9 respiratory coral4 5079, 498 1270, 127 1270, 119 1269, 121 1270, 131 -0.00541 0.0485 0.911 0.04038 0.995 0.904 1.09 -0.0671 0.134 0.616 0.2106 0.935 0.72 1.22 -0.0649 0.135 0.632 0.1996 0.937 0.719 1.22 -0.0597 0.137 0.664 0.1779 0.942 0.72 1.23 PRS_PLINK_0.0199526231496888 FALSE 498 Acute bronchospasm Both 128 1386 9 respiratory coral4 1386, 128 347, 33 346, 34 346, 27 347, 34 0.0766 0.0941 0.416 0.3813 1.08 0.898 1.3 0.0826 0.253 0.744 0.1283 1.09 0.661 1.78 -0.109 0.269 0.685 0.1641 0.897 0.53 1.52 0.0382 0.266 0.886 0.0526 1.04 0.617 1.75 PRS_PLINK_0.0199526231496888 FALSE 499 Cystic fibrosis Both 54 503 9 respiratory coral4 503, 54 126, 14 126, 13 125, 14 126, 13 -0.00695 0.147 0.962 0.01666 0.993 0.744 1.33 -0.00756 0.401 0.985 0.006591 0.992 0.453 2.18 0.087 0.406 0.831 0.08066 1.09 0.492 2.42 -0.0411 0.44 0.926 0.03359 0.96 0.405 2.27 PRS_PLINK_0.0199526231496888 FALSE 500 Lung disease due to external agents Both 170 1049 9 respiratory coral4 1049, 170 263, 36 262, 44 262, 46 262, 44 0.0936 0.0845 0.268 0.5718 1.1 0.93 1.3 0.184 0.24 0.443 0.3533 1.2 0.751 1.92 0.214 0.243 0.378 0.4227 1.24 0.77 1.99 0.273 0.253 0.28 0.5525 1.31 0.8 2.16 PRS_PLINK_0.0199526231496888 FALSE 500.1 Extrinsic allergic alveolitis Both 29 182 9 respiratory coral4 182, 29 46, 7 45, 10 45, 7 46, 5 -0.234 0.206 0.255 0.5934 0.791 0.528 1.18 0.331 0.516 0.521 0.2833 1.39 0.507 3.83 0.133 0.576 0.817 0.08776 1.14 0.369 3.53 -0.118 0.622 0.85 0.07073 0.889 0.263 3.01 PRS_PLINK_0.0199526231496888 TRUE 500.2 Pneumoconiosis Both 20 101 9 respiratory coral4 101, 20 26, 4 25, 3 25, 9 25, 4 -0.133 0.283 0.639 0.1945 0.876 0.503 1.52 0.218 0.809 0.787 0.1038 1.24 0.255 6.07 0.969 0.717 0.176 0.7537 2.64 0.647 10.7 -0.034 0.82 0.967 0.01459 0.967 0.194 4.83 PRS_PLINK_0.0199526231496888 TRUE 501 Pneumonitis due to inhalation of food or vomitus Both 185 1087 9 respiratory coral4 1087, 185 272, 45 272, 43 271, 52 272, 44 -0.0116 0.0799 0.884 0.05345 0.988 0.845 1.16 -0.047 0.231 0.839 0.0764 0.954 0.607 1.5 0.14 0.222 0.526 0.2787 1.15 0.745 1.78 -0.0197 0.236 0.933 0.02991 0.98 0.617 1.56 PRS_PLINK_0.0199526231496888 FALSE 502 Postinflammatory pulmonary fibrosis Both 235 1490 9 respiratory coral4 1490, 235 373, 50 372, 54 372, 62 373, 68 0.0928 0.0735 0.206 0.6855 1.1 0.95 1.27 0.0507 0.209 0.808 0.09243 1.05 0.698 1.58 0.203 0.205 0.324 0.4896 1.22 0.819 1.83 0.275 0.206 0.184 0.736 1.32 0.878 1.97 PRS_PLINK_0.0199526231496888 FALSE 503 Pulmonary congestion and hypostasis Both 284 1534 9 respiratory coral4 1534, 284 384, 53 383, 75 383, 77 384, 79 0.163 0.0668 0.0149 1.825 1.18 1.03 1.34 0.309 0.195 0.114 0.9433 1.36 0.929 2 0.374 0.197 0.058 1.236 1.45 0.987 2.14 0.406 0.203 0.0457 1.34 1.5 1.01 2.24 PRS_PLINK_0.0199526231496888 FALSE 504 Other alveolar and parietoalveolar pneumonopathy Both 183 1106 9 respiratory coral4 1106, 183 277, 36 276, 42 276, 48 277, 56 0.151 0.0821 0.0651 1.186 1.16 0.991 1.37 0.119 0.243 0.626 0.2037 1.13 0.699 1.81 0.265 0.239 0.267 0.5741 1.3 0.816 2.08 0.416 0.237 0.079 1.102 1.52 0.953 2.41 PRS_PLINK_0.0199526231496888 FALSE 504.1 Idiopathic fibrosing alveolitis Both 103 541 9 respiratory coral4 541, 103 136, 25 135, 29 135, 38 135, 11 -0.129 0.11 0.24 0.6197 0.879 0.709 1.09 0.0513 0.304 0.866 0.06234 1.05 0.58 1.91 0.356 0.29 0.221 0.6562 1.43 0.808 2.52 -0.86 0.382 0.0241 1.618 0.423 0.2 0.893 PRS_PLINK_0.0199526231496888 FALSE 505 Other pulmonary inflamation or edema Both 517 2986 9 respiratory coral4 2986, 517 747, 104 746, 116 746, 129 747, 168 0.219 0.0498 1.15e-05 4.941 1.24 1.13 1.37 0.0943 0.146 0.519 0.2851 1.1 0.825 1.46 0.185 0.146 0.203 0.6921 1.2 0.905 1.6 0.488 0.142 0.000612 3.214 1.63 1.23 2.15 PRS_PLINK_0.0199526231496888 FALSE 506 Empyema and pneumothorax Both 1043 5313 9 respiratory coral4 5313, 1043 1329, 249 1328, 234 1328, 277 1328, 283 0.101 0.035 0.00386 2.414 1.11 1.03 1.19 -0.0541 0.1 0.59 0.2292 0.947 0.778 1.15 0.119 0.0982 0.227 0.6448 1.13 0.929 1.37 0.161 0.101 0.111 0.9554 1.17 0.964 1.43 PRS_PLINK_0.0199526231496888 FALSE 507 Pleurisy; pleural effusion Both 1009 5672 9 respiratory coral4 5672, 1009 1418, 257 1418, 232 1418, 267 1418, 252 0.0379 0.0353 0.283 0.5483 1.04 0.969 1.11 -0.0807 0.0997 0.418 0.3786 0.922 0.759 1.12 0.0456 0.0978 0.641 0.193 1.05 0.864 1.27 0.0411 0.102 0.687 0.163 1.04 0.853 1.27 PRS_PLINK_0.0199526231496888 FALSE 508 Pulmonary collapse; interstitial and compensatory emphysema Both 728 4673 9 respiratory coral4 4673, 728 1169, 176 1168, 165 1168, 195 1168, 192 0.0891 0.0411 0.0301 1.521 1.09 1.01 1.18 -0.0579 0.117 0.622 0.2065 0.944 0.75 1.19 0.0925 0.114 0.418 0.379 1.1 0.877 1.37 0.143 0.117 0.222 0.6533 1.15 0.917 1.45 PRS_PLINK_0.0199526231496888 FALSE 509 Respiratory failure, insufficiency, arrest Both 1275 6454 9 respiratory coral4 6454, 1275 1614, 290 1613, 305 1613, 327 1614, 352 0.109 0.0321 0.000699 3.156 1.12 1.05 1.19 0.0596 0.0919 0.517 0.2868 1.06 0.886 1.27 0.129 0.0915 0.16 0.7962 1.14 0.951 1.36 0.235 0.0932 0.0117 1.931 1.26 1.05 1.52 PRS_PLINK_0.0199526231496888 FALSE 509.1 Respiratory failure Both 647 3769 9 respiratory coral4 3769, 647 943, 142 942, 164 942, 161 942, 179 0.111 0.0442 0.0123 1.91 1.12 1.02 1.22 0.146 0.125 0.241 0.6183 1.16 0.906 1.48 0.13 0.127 0.305 0.5162 1.14 0.889 1.46 0.24 0.127 0.0596 1.225 1.27 0.99 1.63 PRS_PLINK_0.0199526231496888 FALSE 509.2 Respiratory insufficiency Both 394 2230 9 respiratory coral4 2230, 394 558, 90 557, 107 557, 88 558, 109 0.122 0.0572 0.0328 1.484 1.13 1.01 1.26 0.188 0.158 0.233 0.6329 1.21 0.886 1.65 -0.032 0.165 0.846 0.07256 0.969 0.701 1.34 0.266 0.163 0.102 0.9894 1.3 0.948 1.79 PRS_PLINK_0.0199526231496888 FALSE 509.3 Pulmonary insufficiency or respiratory failure following trauma and surgery Both 582 3168 9 respiratory coral4 3168, 582 792, 120 792, 118 792, 168 792, 176 0.163 0.0465 0.000472 3.326 1.18 1.07 1.29 -0.0133 0.14 0.925 0.03402 0.987 0.75 1.3 0.344 0.133 0.00952 2.021 1.41 1.09 1.83 0.385 0.136 0.00472 2.326 1.47 1.13 1.92 PRS_PLINK_0.0199526231496888 FALSE 509.8 Dependence on respirator [Ventilator] or supplemental oxygen Both 529 3301 9 respiratory coral4 3301, 529 826, 125 825, 134 825, 116 825, 153 0.099 0.0482 0.0401 1.397 1.1 1 1.21 0.08 0.135 0.554 0.2561 1.08 0.831 1.41 -0.0799 0.14 0.57 0.2444 0.923 0.701 1.22 0.243 0.138 0.078 1.108 1.27 0.973 1.67 PRS_PLINK_0.0199526231496888 FALSE 510 Other diseases of lung Both 1481 8972 9 respiratory coral4 8972, 1481 2242, 347 2243, 346 2243, 413 2243, 375 0.0635 0.029 0.0285 1.545 1.07 1.01 1.13 0.0181 0.0828 0.827 0.08242 1.02 0.866 1.2 0.174 0.0813 0.0327 1.485 1.19 1.01 1.4 0.163 0.0851 0.0558 1.253 1.18 0.996 1.39 PRS_PLINK_0.0199526231496888 FALSE 510.2 Lung transplant Both 51 412 9 respiratory coral4 412, 51 103, 15 103, 13 103, 14 103, 9 -0.214 0.151 0.155 0.8092 0.807 0.601 1.08 -0.184 0.392 0.639 0.1945 0.832 0.386 1.79 -0.00588 0.398 0.988 0.005153 0.994 0.456 2.17 -0.577 0.453 0.203 0.6934 0.561 0.231 1.36 PRS_PLINK_0.0199526231496888 FALSE 512 Other symptoms of respiratory system Both 5283 7555 9 respiratory coral4 7555, 5283 1889, 1339 1889, 1307 1888, 1358 1889, 1278 0.0298 0.0189 0.114 0.9441 1.03 0.993 1.07 0.0104 0.0521 0.842 0.07449 1.01 0.912 1.12 0.065 0.0526 0.217 0.6638 1.07 0.963 1.18 0.0325 0.0547 0.552 0.2578 1.03 0.928 1.15 PRS_PLINK_0.0199526231496888 FALSE 512.1 Wheezing Both 338 3309 9 respiratory coral4 3309, 338 828, 88 827, 69 827, 99 827, 82 0.0207 0.0588 0.725 0.1399 1.02 0.91 1.15 -0.241 0.168 0.15 0.823 0.786 0.566 1.09 0.144 0.156 0.357 0.4472 1.15 0.85 1.57 0.00441 0.167 0.979 0.009259 1 0.724 1.39 PRS_PLINK_0.0199526231496888 FALSE 512.2 Painful respiration Both 716 5639 9 respiratory coral4 5639, 716 1410, 182 1410, 173 1409, 190 1410, 170 0.0306 0.0412 0.458 0.3394 1.03 0.951 1.12 -0.0248 0.113 0.826 0.08278 0.975 0.781 1.22 0.0638 0.113 0.571 0.2433 1.07 0.855 1.33 -0.0588 0.118 0.619 0.208 0.943 0.748 1.19 PRS_PLINK_0.0199526231496888 FALSE 512.3 Abnormal chest sounds Both 72 526 9 respiratory coral4 526, 72 132, 17 131, 13 131, 19 132, 23 0.238 0.127 0.0615 1.211 1.27 0.989 1.63 -0.189 0.39 0.627 0.2028 0.827 0.385 1.78 0.111 0.365 0.761 0.1186 1.12 0.546 2.29 0.259 0.357 0.469 0.3291 1.3 0.643 2.61 PRS_PLINK_0.0199526231496888 FALSE 512.7 Shortness of breath Both 2872 7531 9 respiratory coral4 7531, 2872 1883, 715 1883, 722 1882, 731 1883, 703 0.0502 0.0233 0.0314 1.504 1.05 1 1.1 0.0591 0.0645 0.359 0.4448 1.06 0.935 1.2 0.0773 0.0656 0.239 0.622 1.08 0.95 1.23 0.0909 0.068 0.181 0.7416 1.1 0.959 1.25 PRS_PLINK_0.0199526231496888 FALSE 512.8 Cough Both 2679 7553 9 respiratory coral4 7553, 2679 1889, 677 1888, 683 1888, 663 1888, 656 0.0286 0.0236 0.225 0.647 1.03 0.983 1.08 0.0459 0.0647 0.478 0.3207 1.05 0.922 1.19 0.019 0.0661 0.774 0.1111 1.02 0.895 1.16 0.0508 0.068 0.455 0.342 1.05 0.921 1.2 PRS_PLINK_0.0199526231496888 FALSE 512.9 Other dyspnea Both 3042 7537 9 respiratory coral4 7537, 3042 1885, 778 1884, 718 1884, 785 1884, 760 0.0558 0.0227 0.0139 1.858 1.06 1.01 1.11 -0.0367 0.0633 0.562 0.2501 0.964 0.852 1.09 0.0717 0.0636 0.26 0.5855 1.07 0.948 1.22 0.0707 0.0657 0.281 0.5505 1.07 0.944 1.22 PRS_PLINK_0.0199526231496888 FALSE 513 Respiratory abnormalities Both 3635 9194 9 respiratory coral4 9194, 3635 2299, 898 2298, 873 2298, 982 2299, 881 0.0402 0.0208 0.0527 1.278 1.04 1 1.08 0.00453 0.058 0.938 0.02793 1 0.897 1.13 0.133 0.0576 0.0212 1.673 1.14 1.02 1.28 0.0461 0.0607 0.448 0.3486 1.05 0.93 1.18 PRS_PLINK_0.0199526231496888 FALSE 513.3 Hypoventilation Both 220 1892 9 respiratory coral4 1892, 220 473, 60 473, 41 473, 56 473, 63 0.0624 0.0739 0.398 0.3996 1.06 0.921 1.23 -0.357 0.215 0.0968 1.014 0.699 0.459 1.07 -0.0169 0.2 0.933 0.0302 0.983 0.664 1.46 0.0665 0.203 0.744 0.1285 1.07 0.717 1.59 PRS_PLINK_0.0199526231496888 FALSE 513.31 Apnea Both 108 1025 9 respiratory coral4 1025, 108 257, 31 256, 21 256, 28 256, 28 -0.0254 0.102 0.804 0.09471 0.975 0.798 1.19 -0.429 0.294 0.144 0.8431 0.651 0.366 1.16 -0.0515 0.275 0.851 0.06992 0.95 0.554 1.63 -0.0914 0.284 0.748 0.1263 0.913 0.523 1.59 PRS_PLINK_0.0199526231496888 FALSE 513.32 Orthopnea Both 58 381 9 respiratory coral4 381, 58 96, 15 95, 11 95, 17 95, 15 0.169 0.156 0.277 0.5571 1.18 0.873 1.61 -0.183 0.436 0.674 0.1714 0.832 0.354 1.96 0.395 0.416 0.342 0.4654 1.48 0.657 3.35 0.178 0.423 0.673 0.1717 1.2 0.521 2.74 PRS_PLINK_0.0199526231496888 FALSE 513.4 Hyperventilation Both 177 1038 9 respiratory coral4 1038, 177 260, 45 259, 34 259, 49 260, 49 0.0993 0.0854 0.245 0.6106 1.1 0.934 1.31 -0.289 0.244 0.237 0.6254 0.749 0.464 1.21 0.028 0.228 0.902 0.04472 1.03 0.658 1.61 0.0815 0.24 0.734 0.1344 1.08 0.678 1.74 PRS_PLINK_0.0199526231496888 FALSE 513.8 Disorders of diaphragm Both 64 464 9 respiratory coral4 464, 64 116, 20 116, 19 116, 15 116, 10 -0.275 0.135 0.0416 1.38 0.76 0.583 0.99 -0.054 0.348 0.877 0.05718 0.947 0.479 1.87 -0.297 0.366 0.417 0.3797 0.743 0.363 1.52 -0.771 0.421 0.0671 1.173 0.463 0.203 1.06 PRS_PLINK_0.0199526231496888 FALSE 514 Abnormal findings examination of lungs Both 1376 8545 9 respiratory coral4 8545, 1376 2137, 374 2136, 291 2136, 353 2136, 357 0.0319 0.03 0.289 0.5397 1.03 0.973 1.09 -0.219 0.085 0.01 1.999 0.803 0.68 0.949 -0.0338 0.0825 0.682 0.1662 0.967 0.822 1.14 0.0137 0.0847 0.872 0.05958 1.01 0.859 1.2 PRS_PLINK_0.0199526231496888 FALSE 514.1 Abnormal results of function study of pulmonary system Both 80 590 9 respiratory coral4 590, 80 148, 19 147, 24 147, 17 148, 20 0.0188 0.126 0.881 0.05488 1.02 0.796 1.3 0.135 0.337 0.688 0.1627 1.14 0.592 2.22 -0.227 0.354 0.521 0.2831 0.797 0.398 1.59 0.151 0.364 0.679 0.168 1.16 0.569 2.37 PRS_PLINK_0.0199526231496888 FALSE 514.2 Solitary pulmonary nodule Both 747 6035 9 respiratory coral4 6035, 747 1509, 201 1509, 167 1508, 185 1509, 194 0.0129 0.04 0.747 0.1268 1.01 0.937 1.1 -0.172 0.111 0.122 0.9139 0.842 0.677 1.05 -0.08 0.11 0.468 0.3299 0.923 0.744 1.15 -0.00218 0.112 0.985 0.006772 0.998 0.801 1.24 PRS_PLINK_0.0199526231496888 FALSE 516 Abnormal sputum Both 215 1666 9 respiratory coral4 1666, 215 417, 47 416, 63 416, 49 417, 56 0.0476 0.0744 0.522 0.2826 1.05 0.907 1.21 0.29 0.203 0.153 0.8141 1.34 0.897 1.99 -0.0134 0.218 0.951 0.02181 0.987 0.643 1.51 0.153 0.217 0.48 0.3187 1.17 0.762 1.78 PRS_PLINK_0.0199526231496888 FALSE 516.1 Hemoptysis Both 179 1414 9 respiratory coral4 1414, 179 354, 46 353, 49 353, 40 354, 44 -0.0298 0.0819 0.716 0.1451 0.971 0.827 1.14 0.0651 0.217 0.764 0.1168 1.07 0.697 1.63 -0.176 0.232 0.447 0.3494 0.838 0.532 1.32 -0.0772 0.231 0.738 0.1319 0.926 0.589 1.46 PRS_PLINK_0.0199526231496888 FALSE 519 Other diseases of respiratory system, not elsewhere classified Both 1939 10380 9 respiratory coral4 10380, 1939 2595, 482 2595, 454 2595, 506 2595, 496 0.0513 0.0258 0.0471 1.327 1.05 1 1.11 -0.03 0.0725 0.678 0.1685 0.97 0.842 1.12 0.077 0.0719 0.284 0.5464 1.08 0.938 1.24 0.123 0.0745 0.0991 1.004 1.13 0.977 1.31 PRS_PLINK_0.0199526231496888 FALSE 519.1 Tracheostomy complications Both 49 477 9 respiratory coral4 477, 49 120, 15 119, 10 119, 15 119, 9 -0.0546 0.154 0.723 0.1406 0.947 0.7 1.28 -0.333 0.414 0.421 0.3755 0.717 0.319 1.61 0.0104 0.378 0.978 0.009658 1.01 0.482 2.12 -0.303 0.434 0.485 0.3146 0.738 0.315 1.73 PRS_PLINK_0.0199526231496888 TRUE 519.2 Respiratory complications Both 177 962 9 respiratory coral4 962, 177 241, 46 240, 48 240, 40 241, 43 -0.0188 0.0805 0.816 0.08848 0.981 0.838 1.15 0.0644 0.227 0.777 0.1096 1.07 0.683 1.66 -0.0354 0.238 0.882 0.0547 0.965 0.606 1.54 0.0274 0.241 0.91 0.04118 1.03 0.641 1.65 PRS_PLINK_0.0199526231496888 FALSE 519.8 Other diseases of respiratory system, NEC Both 431 3924 9 respiratory coral4 3924, 431 981, 106 981, 110 981, 110 981, 104 0.0313 0.0528 0.553 0.257 1.03 0.93 1.14 0.0361 0.143 0.801 0.09615 1.04 0.783 1.37 0.0374 0.144 0.796 0.09907 1.04 0.782 1.38 0.0276 0.151 0.855 0.06791 1.03 0.764 1.38 PRS_PLINK_0.0199526231496888 FALSE 519.9 Symptoms involving respiratory system and other chest symptoms Both 1432 8463 9 respiratory coral4 8463, 1432 2116, 358 2116, 313 2115, 368 2116, 393 0.0606 0.0297 0.0412 1.385 1.06 1 1.13 -0.12 0.0845 0.156 0.806 0.887 0.752 1.05 0.0363 0.0828 0.661 0.1797 1.04 0.882 1.22 0.151 0.0838 0.0717 1.144 1.16 0.987 1.37 PRS_PLINK_0.0199526231496888 FALSE 520 Disorders of tooth development Both 117 1100 10 digestive chartreuse4 1100, 117 275, 36 275, 27 275, 31 275, 23 -0.14 0.0984 0.155 0.8088 0.87 0.717 1.05 -0.213 0.266 0.423 0.3741 0.808 0.48 1.36 -0.0869 0.26 0.738 0.132 0.917 0.551 1.53 -0.432 0.292 0.139 0.8561 0.65 0.367 1.15 PRS_PLINK_0.0199526231496888 FALSE 520.1 Hereditary disturbances in tooth structure Both 45 421 10 digestive chartreuse4 421, 45 106, 11 105, 10 105, 14 105, 10 -0.0169 0.156 0.914 0.03909 0.983 0.724 1.34 -0.115 0.444 0.796 0.09897 0.892 0.373 2.13 0.321 0.417 0.442 0.3549 1.38 0.609 3.12 -0.106 0.446 0.812 0.09056 0.899 0.375 2.16 PRS_PLINK_0.0199526231496888 TRUE 520.2 Disturbances in tooth eruption Both 77 723 10 digestive chartreuse4 723, 77 181, 28 181, 15 180, 21 181, 13 -0.245 0.125 0.0494 1.307 0.783 0.613 0.999 -0.514 0.337 0.127 0.897 0.598 0.309 1.16 -0.34 0.311 0.274 0.5629 0.712 0.387 1.31 -0.816 0.378 0.0308 1.512 0.442 0.211 0.927 PRS_PLINK_0.0199526231496888 FALSE 521 Diseases of hard tissues of teeth Both 276 2354 10 digestive chartreuse4 2354, 276 589, 61 588, 62 588, 77 589, 76 0.0968 0.0651 0.137 0.8621 1.1 0.97 1.25 0.0384 0.189 0.839 0.07635 1.04 0.718 1.5 0.222 0.183 0.225 0.6484 1.25 0.873 1.79 0.188 0.189 0.32 0.4954 1.21 0.833 1.75 PRS_PLINK_0.0199526231496888 FALSE 521.1 Dental caries Both 262 2192 10 digestive chartreuse4 2192, 262 548, 66 548, 52 548, 74 548, 70 0.0769 0.0674 0.254 0.5957 1.08 0.946 1.23 -0.215 0.194 0.269 0.5704 0.807 0.551 1.18 0.115 0.181 0.524 0.2807 1.12 0.787 1.6 0.00105 0.19 0.996 0.001921 1 0.69 1.45 PRS_PLINK_0.0199526231496888 FALSE 521.2 Dental abrasion, erosion and attrition Both 14 134 10 digestive chartreuse4 134, 14 34, 1 33, 5 33, 3 34, 5 0.515 0.321 0.109 0.9625 1.67 0.892 3.14 1.39 0.864 0.108 0.9669 4.01 0.737 21.8 0.988 1.06 0.351 0.4542 2.69 0.336 21.5 1.43 0.9 0.113 0.9481 4.17 0.714 24.3 PRS_PLINK_0.0199526231496888 TRUE 522 Diseases of pulp and periapical tissues Both 164 1509 10 digestive chartreuse4 1509, 164 378, 42 377, 30 377, 50 377, 41 -0.0156 0.0825 0.85 0.07064 0.985 0.838 1.16 -0.319 0.245 0.193 0.7144 0.727 0.449 1.18 0.143 0.224 0.524 0.2807 1.15 0.744 1.79 -0.0441 0.239 0.853 0.06887 0.957 0.599 1.53 PRS_PLINK_0.0199526231496888 FALSE 522.5 Periapical abscess Both 137 1304 10 digestive chartreuse4 1304, 137 326, 37 326, 25 326, 38 326, 36 -0.0661 0.0906 0.466 0.3318 0.936 0.784 1.12 -0.373 0.264 0.158 0.8015 0.688 0.41 1.16 -0.0185 0.245 0.94 0.02698 0.982 0.607 1.59 -0.164 0.256 0.522 0.2825 0.849 0.514 1.4 PRS_PLINK_0.0199526231496888 FALSE 523 Gingival and periodontal diseases Both 201 1915 10 digestive chartreuse4 1915, 201 479, 47 479, 42 478, 59 479, 53 0.0576 0.0764 0.451 0.3463 1.06 0.912 1.23 -0.0866 0.221 0.695 0.1582 0.917 0.595 1.41 0.252 0.209 0.227 0.644 1.29 0.855 1.94 0.0821 0.22 0.709 0.1495 1.09 0.706 1.67 PRS_PLINK_0.0199526231496888 FALSE 523.1 Gingivitis Both 47 414 10 digestive chartreuse4 414, 47 104, 13 103, 8 103, 12 104, 14 0.0947 0.163 0.561 0.2509 1.1 0.799 1.51 -0.292 0.45 0.516 0.2874 0.747 0.309 1.8 0.163 0.436 0.708 0.15 1.18 0.501 2.76 -0.187 0.436 0.668 0.1752 0.829 0.353 1.95 PRS_PLINK_0.0199526231496888 TRUE 523.3 Periodontitis (acute or chronic) Both 102 982 10 digestive chartreuse4 982, 102 246, 28 245, 15 245, 31 246, 28 -0.00876 0.11 0.936 0.0285 0.991 0.799 1.23 -0.594 0.321 0.0642 1.193 0.552 0.294 1.04 0.0908 0.277 0.743 0.1292 1.1 0.637 1.88 0.0587 0.289 0.839 0.07621 1.06 0.602 1.87 PRS_PLINK_0.0199526231496888 FALSE 523.31 Acute periodontitis Both 79 845 10 digestive chartreuse4 845, 79 212, 25 211, 11 211, 22 211, 21 -0.0987 0.125 0.428 0.3681 0.906 0.71 1.16 -0.762 0.359 0.0337 1.472 0.467 0.231 0.943 -0.135 0.307 0.66 0.1805 0.873 0.478 1.6 -0.196 0.322 0.542 0.2657 0.822 0.437 1.54 PRS_PLINK_0.0199526231496888 FALSE 523.32 Chronic periodontitis Both 36 277 10 digestive chartreuse4 277, 36 70, 7 69, 7 69, 12 69, 10 0.149 0.179 0.404 0.3933 1.16 0.818 1.65 -0.115 0.532 0.829 0.08129 0.892 0.314 2.53 0.667 0.506 0.187 0.7274 1.95 0.723 5.25 0.458 0.515 0.374 0.4267 1.58 0.576 4.34 PRS_PLINK_0.0199526231496888 TRUE 524 Dentofacial anomalies, including malocclusion Both 119 1276 10 digestive chartreuse4 1276, 119 319, 38 319, 27 319, 34 319, 20 -0.165 0.102 0.104 0.9834 0.848 0.695 1.03 -0.291 0.26 0.264 0.5788 0.748 0.449 1.25 -0.0701 0.251 0.78 0.1081 0.932 0.571 1.52 -0.59 0.296 0.0463 1.335 0.554 0.31 0.99 PRS_PLINK_0.0199526231496888 FALSE 524.3 Anomalies of tooth position/malocclusion Both 77 782 10 digestive chartreuse4 782, 77 196, 25 195, 20 195, 23 196, 9 -0.231 0.125 0.0636 1.197 0.794 0.622 1.01 -0.114 0.314 0.716 0.1452 0.892 0.482 1.65 -0.0496 0.312 0.874 0.05863 0.952 0.516 1.76 -0.871 0.405 0.0313 1.505 0.418 0.189 0.925 PRS_PLINK_0.0199526231496888 FALSE 525 Other diseases of the teeth and supporting structures Both 309 2989 10 digestive chartreuse4 2989, 309 748, 76 747, 63 747, 85 747, 85 0.113 0.0615 0.0653 1.185 1.12 0.993 1.26 -0.151 0.177 0.394 0.4045 0.86 0.608 1.22 0.118 0.167 0.477 0.3216 1.13 0.812 1.56 0.143 0.172 0.405 0.3925 1.15 0.824 1.62 PRS_PLINK_0.0199526231496888 FALSE 525.1 Loss of teeth or edentulism Both 97 1038 10 digestive chartreuse4 1038, 97 260, 28 259, 18 259, 31 260, 20 -0.0302 0.11 0.785 0.1054 0.97 0.781 1.2 -0.443 0.306 0.148 0.8305 0.642 0.352 1.17 0.0707 0.275 0.797 0.09859 1.07 0.626 1.84 -0.233 0.313 0.457 0.3397 0.792 0.429 1.46 PRS_PLINK_0.0199526231496888 FALSE 526 Diseases of the jaws Both 846 8062 10 digestive chartreuse4 8062, 846 2016, 237 2015, 197 2015, 227 2016, 185 -0.0811 0.0377 0.0317 1.499 0.922 0.856 0.993 -0.167 0.102 0.101 0.9969 0.846 0.694 1.03 -0.0336 0.0998 0.736 0.1329 0.967 0.795 1.18 -0.225 0.108 0.0366 1.436 0.799 0.647 0.986 PRS_PLINK_0.0199526231496888 FALSE 526.1 Cysts of the jaws Both 41 660 10 digestive chartreuse4 660, 41 165, 18 165, 7 165, 8 165, 8 -0.273 0.171 0.11 0.9576 0.761 0.544 1.06 -1.05 0.437 0.0166 1.779 0.351 0.149 0.827 -0.992 0.442 0.0249 1.604 0.371 0.156 0.882 -0.663 0.443 0.135 0.8702 0.515 0.216 1.23 PRS_PLINK_0.0199526231496888 TRUE 526.3 Anomalies of jaw size/symmetry Both 98 883 10 digestive chartreuse4 883, 98 221, 36 221, 23 220, 28 221, 11 -0.319 0.11 0.00372 2.43 0.727 0.586 0.902 -0.379 0.282 0.179 0.7476 0.684 0.394 1.19 -0.249 0.275 0.365 0.4377 0.779 0.455 1.34 -1.04 0.362 0.00406 2.392 0.353 0.174 0.718 PRS_PLINK_0.0199526231496888 FALSE 526.4 Temporomandibular joint disorders Both 532 4941 10 digestive chartreuse4 4941, 532 1236, 151 1235, 133 1235, 135 1235, 113 -0.106 0.0475 0.0262 1.582 0.9 0.82 0.988 -0.104 0.126 0.409 0.388 0.901 0.705 1.15 -0.117 0.127 0.357 0.4478 0.89 0.694 1.14 -0.272 0.137 0.047 1.328 0.762 0.583 0.996 PRS_PLINK_0.0199526231496888 FALSE 526.41 Temporomandibular joint disorder, unspecified Both 436 3981 10 digestive chartreuse4 3981, 436 996, 122 995, 102 995, 103 995, 109 -0.0719 0.0525 0.171 0.7677 0.931 0.84 1.03 -0.156 0.141 0.268 0.5721 0.855 0.649 1.13 -0.167 0.143 0.243 0.6141 0.846 0.64 1.12 -0.0831 0.146 0.568 0.2455 0.92 0.692 1.22 PRS_PLINK_0.0199526231496888 FALSE 526.42 Arthralgia/ankylosis of temporomandibular joint Both 269 2609 10 digestive chartreuse4 2609, 269 653, 83 652, 61 652, 75 652, 50 -0.184 0.067 0.00593 2.227 0.832 0.729 0.948 -0.302 0.177 0.0882 1.055 0.739 0.522 1.05 -0.125 0.171 0.465 0.3328 0.882 0.631 1.23 -0.489 0.196 0.0127 1.895 0.613 0.418 0.901 PRS_PLINK_0.0199526231496888 FALSE 526.5 Inflammatory conditions of jaw Both 77 779 10 digestive chartreuse4 779, 77 195, 19 195, 17 194, 28 195, 13 -0.0625 0.124 0.616 0.2106 0.939 0.736 1.2 -0.0991 0.344 0.773 0.1118 0.906 0.462 1.78 0.417 0.315 0.185 0.7318 1.52 0.818 2.82 -0.42 0.375 0.264 0.5791 0.657 0.315 1.37 PRS_PLINK_0.0199526231496888 FALSE 526.8 Exostosis of jaw Both 14 123 10 digestive chartreuse4 123, 14 31, 4 31, 1 30, 4 31, 5 0.109 0.304 0.719 0.1434 1.12 0.615 2.02 -1.32 1.01 0.19 0.7204 0.266 0.0367 1.93 -0.366 0.8 0.647 0.189 0.693 0.144 3.33 0.313 0.767 0.683 0.1657 1.37 0.304 6.15 PRS_PLINK_0.0199526231496888 TRUE 526.9 Jaw disease NOS Both 125 1323 10 digestive chartreuse4 1323, 125 331, 32 331, 23 330, 44 331, 26 0.0237 0.101 0.813 0.08972 1.02 0.841 1.25 -0.328 0.277 0.237 0.6259 0.72 0.418 1.24 0.372 0.245 0.129 0.8888 1.45 0.897 2.34 -0.169 0.277 0.541 0.2667 0.844 0.491 1.45 PRS_PLINK_0.0199526231496888 FALSE 527 Diseases of the salivary glands Both 401 4358 10 digestive chartreuse4 4358, 401 1089, 113 1089, 97 1089, 96 1090, 95 -0.0501 0.0537 0.351 0.4549 0.951 0.856 1.06 -0.133 0.145 0.359 0.4444 0.875 0.658 1.16 -0.158 0.147 0.284 0.5472 0.854 0.64 1.14 -0.124 0.152 0.416 0.381 0.884 0.656 1.19 PRS_PLINK_0.0199526231496888 FALSE 527.1 Hypertrophy of salivary gland Both 10 149 10 digestive chartreuse4 149, 10 38, 1 37, 1 37, 4 37, 4 0.728 0.351 0.0379 1.421 2.07 1.04 4.12 -0.0704 0.91 0.938 0.02766 0.932 0.157 5.54 0.589 0.953 0.536 0.2705 1.8 0.279 11.7 1.04 0.849 0.221 0.6563 2.83 0.536 14.9 PRS_PLINK_0.0199526231496888 TRUE 527.2 Sialoadenitis Both 83 1053 10 digestive chartreuse4 1053, 83 264, 25 263, 20 263, 15 263, 23 -0.055 0.115 0.631 0.2 0.946 0.756 1.18 -0.23 0.307 0.453 0.3439 0.794 0.435 1.45 -0.492 0.33 0.136 0.8651 0.612 0.32 1.17 -0.0197 0.307 0.949 0.02285 0.98 0.537 1.79 PRS_PLINK_0.0199526231496888 FALSE 527.7 Disturbance of salivary secretion Both 226 2084 10 digestive chartreuse4 2084, 226 521, 67 521, 57 521, 55 521, 47 -0.119 0.0719 0.0971 1.013 0.888 0.771 1.02 -0.125 0.19 0.511 0.2919 0.882 0.608 1.28 -0.227 0.194 0.242 0.6153 0.797 0.545 1.17 -0.335 0.208 0.107 0.9703 0.715 0.476 1.08 PRS_PLINK_0.0199526231496888 FALSE 527.8 Other specified diseases of the salivary glands Both 43 581 10 digestive chartreuse4 581, 43 145, 11 145, 13 145, 9 145, 10 -0.076 0.154 0.621 0.207 0.927 0.686 1.25 0.16 0.405 0.694 0.1587 1.17 0.53 2.6 -0.277 0.438 0.527 0.278 0.758 0.321 1.79 0.083 0.439 0.85 0.07058 1.09 0.46 2.57 PRS_PLINK_0.0199526231496888 TRUE 528 Diseases of the oral soft tissues, excluding lesions specific for gingiva and tongue Both 726 6956 10 digestive chartreuse4 6956, 726 1738, 209 1739, 164 1739, 195 1739, 158 -0.075 0.0401 0.0612 1.213 0.928 0.858 1 -0.24 0.11 0.0289 1.539 0.786 0.634 0.976 -0.0715 0.107 0.504 0.2975 0.931 0.755 1.15 -0.265 0.116 0.0224 1.651 0.767 0.611 0.963 PRS_PLINK_0.0199526231496888 FALSE 528.1 Stomatitis and mucositis Both 243 1859 10 digestive chartreuse4 1859, 243 465, 72 465, 62 464, 63 465, 46 -0.132 0.0707 0.0613 1.212 0.876 0.763 1.01 -0.123 0.186 0.508 0.294 0.884 0.614 1.27 -0.166 0.189 0.38 0.4204 0.847 0.586 1.23 -0.403 0.207 0.0521 1.283 0.668 0.445 1 PRS_PLINK_0.0199526231496888 FALSE 528.11 Stomatitis and mucositis (ulcerative) Both 69 586 10 digestive chartreuse4 586, 69 147, 18 146, 16 146, 16 147, 19 0.0426 0.129 0.742 0.1295 1.04 0.81 1.34 -0.187 0.353 0.596 0.2249 0.829 0.415 1.66 -0.241 0.354 0.496 0.3043 0.786 0.392 1.57 0.0153 0.36 0.966 0.01498 1.02 0.502 2.05 PRS_PLINK_0.0199526231496888 FALSE 528.12 Oral aphthae Both 86 675 10 digestive chartreuse4 675, 86 169, 26 169, 26 168, 19 169, 15 -0.165 0.118 0.164 0.7849 0.848 0.672 1.07 -0.0713 0.299 0.811 0.09082 0.931 0.519 1.67 -0.253 0.318 0.426 0.3707 0.776 0.416 1.45 -0.418 0.343 0.224 0.6497 0.659 0.336 1.29 PRS_PLINK_0.0199526231496888 FALSE 528.3 Cellulitis and abscess of oral soft tissues Both 57 674 10 digestive chartreuse4 674, 57 169, 13 168, 15 168, 21 169, 8 -0.109 0.137 0.427 0.3699 0.897 0.685 1.17 0.153 0.381 0.688 0.1624 1.17 0.552 2.46 0.52 0.367 0.156 0.8073 1.68 0.82 3.45 -0.831 0.463 0.0726 1.139 0.436 0.176 1.08 PRS_PLINK_0.0199526231496888 FALSE 528.4 Cysts of oral soft tissues Both 26 318 10 digestive chartreuse4 318, 26 80, 9 79, 3 79, 9 80, 5 0.0115 0.22 0.958 0.01853 1.01 0.658 1.56 -0.994 0.602 0.0986 1.006 0.37 0.114 1.2 0.226 0.514 0.661 0.18 1.25 0.458 3.43 -0.585 0.613 0.34 0.4682 0.557 0.167 1.85 PRS_PLINK_0.0199526231496888 TRUE 528.41 Cyst of the salivary gland Both 16 204 10 digestive chartreuse4 204, 16 51, 2 51, 3 51, 7 51, 4 0.392 0.291 0.178 0.7502 1.48 0.837 2.62 0.133 0.738 0.857 0.06722 1.14 0.269 4.85 1.26 0.748 0.0914 1.039 3.54 0.816 15.3 0.762 0.857 0.374 0.4272 2.14 0.4 11.5 PRS_PLINK_0.0199526231496888 TRUE 528.5 Diseases of lips Both 127 1221 10 digestive chartreuse4 1221, 127 306, 35 305, 27 305, 34 305, 31 -0.0616 0.0935 0.51 0.2926 0.94 0.783 1.13 -0.233 0.266 0.381 0.4192 0.792 0.471 1.33 -0.0392 0.256 0.879 0.05625 0.962 0.582 1.59 -0.185 0.27 0.492 0.3084 0.831 0.49 1.41 PRS_PLINK_0.0199526231496888 FALSE 528.6 Leukoplakia of oral mucosa Both 21 282 10 digestive chartreuse4 282, 21 71, 7 70, 6 70, 4 71, 4 -0.191 0.212 0.369 0.4333 0.826 0.545 1.25 -0.146 0.543 0.788 0.1032 0.864 0.298 2.51 -0.316 0.586 0.589 0.2296 0.729 0.231 2.3 -0.548 0.593 0.355 0.4497 0.578 0.181 1.85 PRS_PLINK_0.0199526231496888 TRUE 528.7 Sialolithiasis Both 30 414 10 digestive chartreuse4 414, 30 103, 8 103, 7 103, 11 104, 4 -0.114 0.183 0.533 0.2734 0.892 0.622 1.28 0.357 0.561 0.525 0.2801 1.43 0.476 4.29 0.0611 0.504 0.904 0.04401 1.06 0.396 2.86 -0.362 0.613 0.554 0.2563 0.696 0.209 2.31 PRS_PLINK_0.0199526231496888 TRUE 529 Diseases and other conditions of the tongue Both 174 1626 10 digestive chartreuse4 1626, 174 407, 46 406, 48 406, 39 407, 41 -0.0709 0.0806 0.379 0.4213 0.932 0.795 1.09 0.0816 0.217 0.707 0.1508 1.08 0.71 1.66 -0.156 0.232 0.501 0.2998 0.855 0.542 1.35 -0.0685 0.232 0.768 0.1148 0.934 0.593 1.47 PRS_PLINK_0.0199526231496888 FALSE 529.1 Glossitis Both 37 305 10 digestive chartreuse4 305, 37 77, 10 76, 9 76, 11 76, 7 -0.226 0.166 0.174 0.7602 0.797 0.575 1.1 -0.112 0.471 0.812 0.09042 0.894 0.355 2.25 0.00617 0.469 0.989 0.004585 1.01 0.401 2.52 -0.495 0.518 0.34 0.4687 0.61 0.221 1.68 PRS_PLINK_0.0199526231496888 TRUE 529.6 Glossodynia Both 39 377 10 digestive chartreuse4 377, 39 95, 11 94, 9 94, 7 94, 12 -0.0769 0.171 0.652 0.1856 0.926 0.663 1.29 -0.23 0.474 0.628 0.2022 0.795 0.314 2.01 -0.46 0.49 0.348 0.4586 0.632 0.242 1.65 0.147 0.44 0.738 0.132 1.16 0.489 2.74 PRS_PLINK_0.0199526231496888 TRUE 530 Diseases of esophagus Both 4302 8072 10 digestive chartreuse4 8072, 4302 2018, 1111 2018, 1055 2018, 1088 2018, 1047 0.0163 0.0199 0.411 0.3863 1.02 0.978 1.06 -0.0329 0.0551 0.551 0.2591 0.968 0.869 1.08 0.00467 0.0556 0.933 0.03011 1 0.901 1.12 0.00672 0.0574 0.907 0.04245 1.01 0.9 1.13 PRS_PLINK_0.0199526231496888 FALSE 530.1 Esophagitis, GERD and related diseases Both 4148 8072 10 digestive chartreuse4 8072, 4148 2018, 1073 2018, 1003 2018, 1054 2018, 1017 0.0175 0.0201 0.384 0.4156 1.02 0.978 1.06 -0.0483 0.0558 0.387 0.4118 0.953 0.854 1.06 0.00524 0.0562 0.926 0.03355 1.01 0.9 1.12 0.00965 0.058 0.868 0.06155 1.01 0.901 1.13 PRS_PLINK_0.0199526231496888 FALSE 530.11 GERD Both 4020 8071 10 digestive chartreuse4 8071, 4020 2018, 1034 2018, 979 2017, 1019 2018, 987 0.0198 0.0203 0.329 0.4831 1.02 0.98 1.06 -0.0365 0.0564 0.518 0.2859 0.964 0.863 1.08 0.00926 0.0569 0.871 0.06015 1.01 0.903 1.13 0.0142 0.0587 0.809 0.09187 1.01 0.904 1.14 PRS_PLINK_0.0199526231496888 FALSE 530.12 Ulcer of esophagus Both 90 893 10 digestive chartreuse4 893, 90 224, 21 223, 23 223, 28 223, 17 -0.117 0.112 0.299 0.5242 0.89 0.714 1.11 0.0786 0.309 0.799 0.09738 1.08 0.59 1.98 0.207 0.302 0.492 0.3084 1.23 0.681 2.22 -0.243 0.347 0.483 0.3157 0.784 0.397 1.55 PRS_PLINK_0.0199526231496888 FALSE 530.13 Barrett's esophagus Both 165 1549 10 digestive chartreuse4 1549, 165 388, 37 387, 40 387, 39 387, 49 0.0724 0.0849 0.394 0.4048 1.08 0.91 1.27 0.0418 0.237 0.86 0.06555 1.04 0.656 1.66 0.0308 0.239 0.898 0.04697 1.03 0.645 1.65 0.204 0.237 0.388 0.4107 1.23 0.771 1.95 PRS_PLINK_0.0199526231496888 FALSE 530.14 Reflux esophagitis Both 448 4436 10 digestive chartreuse4 4436, 448 1109, 119 1109, 124 1109, 107 1109, 97 -0.0923 0.0516 0.074 1.131 0.912 0.824 1.01 0.0378 0.135 0.78 0.1077 1.04 0.796 1.35 -0.107 0.142 0.451 0.3462 0.898 0.68 1.19 -0.184 0.15 0.22 0.6583 0.832 0.62 1.12 PRS_PLINK_0.0199526231496888 FALSE 530.15 Eosinophilic esophagitis Both 90 717 10 digestive chartreuse4 717, 90 180, 30 179, 21 179, 20 179, 19 -0.105 0.113 0.35 0.456 0.9 0.722 1.12 -0.287 0.301 0.341 0.4674 0.751 0.416 1.35 -0.411 0.314 0.191 0.7198 0.663 0.359 1.23 -0.449 0.322 0.163 0.7882 0.638 0.339 1.2 PRS_PLINK_0.0199526231496888 FALSE 530.2 Esophageal bleeding (varices/hemorrhage) Both 195 1432 10 digestive chartreuse4 1432, 195 358, 36 358, 52 358, 56 358, 51 0.164 0.0804 0.041 1.388 1.18 1.01 1.38 0.383 0.228 0.0924 1.034 1.47 0.939 2.29 0.471 0.228 0.0383 1.416 1.6 1.03 2.5 0.398 0.24 0.0974 1.011 1.49 0.93 2.38 PRS_PLINK_0.0199526231496888 FALSE 530.3 Stricture and stenosis of esophagus Both 233 1995 10 digestive chartreuse4 1995, 233 499, 63 499, 54 498, 59 499, 56 -0.0395 0.0703 0.574 0.2411 0.961 0.838 1.1 -0.12 0.195 0.54 0.2679 0.887 0.606 1.3 -0.0555 0.192 0.773 0.1119 0.946 0.649 1.38 -0.0297 0.2 0.882 0.05459 0.971 0.656 1.44 PRS_PLINK_0.0199526231496888 FALSE 530.5 Disorders of esophageal motility Both 147 1343 10 digestive chartreuse4 1343, 147 336, 46 336, 37 335, 37 336, 26 -0.171 0.0905 0.0582 1.235 0.842 0.706 1.01 -0.208 0.232 0.37 0.4314 0.812 0.515 1.28 -0.248 0.236 0.293 0.5334 0.78 0.492 1.24 -0.476 0.264 0.0707 1.151 0.621 0.37 1.04 PRS_PLINK_0.0199526231496888 FALSE 530.6 Diverticulum of esophagus, acquired Both 28 222 10 digestive chartreuse4 222, 28 56, 9 55, 9 55, 7 56, 3 -0.354 0.223 0.113 0.9477 0.702 0.454 1.09 -0.034 0.511 0.947 0.02369 0.967 0.355 2.63 -0.32 0.533 0.549 0.2604 0.726 0.255 2.07 -0.976 0.685 0.154 0.8124 0.377 0.0984 1.44 PRS_PLINK_0.0199526231496888 TRUE 530.7 Gastroesophageal laceration-hemorrhage syndrome Both 18 212 10 digestive chartreuse4 212, 18 53, 9 53, 2 53, 2 53, 5 -0.333 0.255 0.191 0.7181 0.717 0.435 1.18 -1.65 0.755 0.0289 1.538 0.192 0.0437 0.844 -1.17 0.725 0.106 0.9759 0.309 0.0746 1.28 -0.519 0.583 0.373 0.4282 0.595 0.19 1.86 PRS_PLINK_0.0199526231496888 TRUE 530.9 Heartburn Both 353 4191 10 digestive chartreuse4 4191, 353 1048, 82 1048, 91 1047, 85 1048, 95 0.0684 0.0567 0.228 0.6418 1.07 0.958 1.2 0.0931 0.158 0.555 0.2558 1.1 0.806 1.5 0.048 0.162 0.767 0.115 1.05 0.763 1.44 0.171 0.164 0.299 0.5239 1.19 0.859 1.64 PRS_PLINK_0.0199526231496888 FALSE 531 Peptic ulcer (excl. esophageal) Both 564 4942 10 digestive chartreuse4 4942, 564 1236, 130 1235, 142 1235, 144 1236, 148 0.0581 0.0459 0.206 0.6867 1.06 0.969 1.16 0.0996 0.128 0.438 0.359 1.1 0.859 1.42 0.0953 0.129 0.462 0.3358 1.1 0.854 1.42 0.0832 0.132 0.53 0.2761 1.09 0.838 1.41 PRS_PLINK_0.0199526231496888 FALSE 531.1 Hemorrhage from gastrointestinal ulcer Both 108 765 10 digestive chartreuse4 765, 108 192, 23 191, 27 191, 31 191, 27 0.135 0.105 0.198 0.7023 1.14 0.932 1.4 0.28 0.305 0.359 0.4451 1.32 0.727 2.41 0.39 0.3 0.193 0.7134 1.48 0.821 2.66 0.167 0.315 0.595 0.2258 1.18 0.638 2.19 PRS_PLINK_0.0199526231496888 FALSE 531.2 Gastric ulcer Both 333 2922 10 digestive chartreuse4 2922, 333 731, 72 730, 76 730, 97 731, 88 0.111 0.0603 0.0665 1.177 1.12 0.992 1.26 0.0621 0.171 0.717 0.1442 1.06 0.76 1.49 0.305 0.165 0.0654 1.184 1.36 0.981 1.88 0.176 0.174 0.312 0.5059 1.19 0.848 1.68 PRS_PLINK_0.0199526231496888 FALSE 531.3 Duodenal ulcer Both 130 909 10 digestive chartreuse4 909, 130 228, 28 227, 34 227, 32 227, 36 0.104 0.0943 0.272 0.5661 1.11 0.922 1.33 0.255 0.271 0.347 0.4595 1.29 0.758 2.2 0.124 0.279 0.655 0.1835 1.13 0.656 1.96 0.263 0.274 0.336 0.4731 1.3 0.761 2.22 PRS_PLINK_0.0199526231496888 FALSE 531.4 Peptic ulcer, site unspecified Both 201 1905 10 digestive chartreuse4 1905, 201 477, 51 476, 51 476, 45 476, 54 0.0348 0.0768 0.651 0.1866 1.04 0.891 1.2 0.00501 0.208 0.981 0.008431 1.01 0.669 1.51 -0.153 0.215 0.476 0.3221 0.858 0.563 1.31 -0.0373 0.213 0.861 0.06499 0.963 0.634 1.46 PRS_PLINK_0.0199526231496888 FALSE 531.5 Gastrojejunal ulcer Both 48 429 10 digestive chartreuse4 429, 48 108, 16 107, 12 107, 8 107, 12 -0.132 0.158 0.403 0.3949 0.876 0.643 1.19 -0.302 0.398 0.448 0.349 0.739 0.339 1.61 -0.528 0.46 0.251 0.6012 0.59 0.239 1.45 -0.264 0.411 0.522 0.2825 0.768 0.343 1.72 PRS_PLINK_0.0199526231496888 TRUE 532 Dysphagia Both 1476 7680 10 digestive chartreuse4 7680, 1476 1920, 365 1920, 350 1920, 393 1920, 367 0.0554 0.0297 0.0617 1.21 1.06 0.997 1.12 -0.0262 0.0835 0.754 0.1226 0.974 0.827 1.15 0.0832 0.0826 0.314 0.5032 1.09 0.924 1.28 0.0719 0.0864 0.405 0.3923 1.07 0.907 1.27 PRS_PLINK_0.0199526231496888 FALSE 535 Gastritis and duodenitis Both 818 7255 10 digestive chartreuse4 7255, 818 1814, 191 1814, 210 1813, 222 1814, 195 0.0032 0.038 0.933 0.03015 1 0.931 1.08 0.0945 0.106 0.37 0.4313 1.1 0.894 1.35 0.135 0.106 0.201 0.6958 1.14 0.93 1.41 -0.0383 0.112 0.733 0.1351 0.962 0.772 1.2 PRS_PLINK_0.0199526231496888 FALSE 535.1 Acute gastritis Both 332 2902 10 digestive chartreuse4 2902, 332 726, 68 725, 80 725, 97 726, 87 0.113 0.0596 0.0588 1.231 1.12 0.996 1.26 0.17 0.172 0.323 0.4912 1.19 0.846 1.66 0.378 0.168 0.0241 1.617 1.46 1.05 2.03 0.204 0.177 0.25 0.6018 1.23 0.866 1.74 PRS_PLINK_0.0199526231496888 FALSE 535.2 Atrophic gastritis Both 110 896 10 digestive chartreuse4 896, 110 224, 28 224, 26 224, 26 224, 30 -0.0335 0.103 0.745 0.128 0.967 0.791 1.18 -0.0616 0.288 0.831 0.08056 0.94 0.534 1.65 -0.17 0.289 0.557 0.2538 0.844 0.479 1.49 -0.185 0.296 0.532 0.2744 0.831 0.465 1.48 PRS_PLINK_0.0199526231496888 FALSE 535.6 Duodenitis Both 79 775 10 digestive chartreuse4 775, 79 194, 17 194, 22 193, 26 194, 14 0.0449 0.12 0.707 0.1503 1.05 0.827 1.32 0.303 0.328 0.356 0.4488 1.35 0.711 2.58 0.433 0.328 0.187 0.727 1.54 0.81 2.93 -0.224 0.372 0.546 0.2626 0.799 0.386 1.66 PRS_PLINK_0.0199526231496888 FALSE 535.8 Other specified gastritis Both 189 1654 10 digestive chartreuse4 1654, 189 414, 48 413, 41 413, 47 414, 53 -0.0486 0.0795 0.541 0.2667 0.953 0.815 1.11 -0.177 0.222 0.426 0.3708 0.838 0.542 1.3 -0.0442 0.221 0.841 0.07497 0.957 0.62 1.48 -0.0645 0.221 0.77 0.1135 0.938 0.608 1.45 PRS_PLINK_0.0199526231496888 FALSE 535.9 Gastritis and duodenitis, NOS Both 389 3390 10 digestive chartreuse4 3390, 389 848, 97 847, 104 847, 93 848, 95 -0.0552 0.056 0.324 0.4889 0.946 0.848 1.06 0.0697 0.149 0.64 0.1935 1.07 0.8 1.44 -0.051 0.155 0.742 0.1294 0.95 0.701 1.29 -0.04 0.159 0.801 0.09635 0.961 0.704 1.31 PRS_PLINK_0.0199526231496888 FALSE 536 Disorders of function of stomach Both 879 7690 10 digestive chartreuse4 7690, 879 1923, 222 1922, 212 1922, 217 1923, 227 0.00535 0.0366 0.884 0.05369 1.01 0.936 1.08 -0.044 0.102 0.665 0.1771 0.957 0.784 1.17 -0.0221 0.103 0.83 0.08111 0.978 0.8 1.2 0.0132 0.105 0.899 0.04604 1.01 0.826 1.24 PRS_PLINK_0.0199526231496888 FALSE 536.3 Gastroparesis Both 216 1990 10 digestive chartreuse4 1990, 216 498, 57 497, 50 497, 52 498, 56 -0.0128 0.0746 0.863 0.06381 0.987 0.853 1.14 -0.108 0.203 0.596 0.2246 0.898 0.603 1.34 -0.042 0.204 0.837 0.07723 0.959 0.642 1.43 0.0142 0.206 0.945 0.02461 1.01 0.678 1.52 PRS_PLINK_0.0199526231496888 FALSE 536.7 Complications of gastrostomy, colostomy and enterostomy Both 150 961 10 digestive chartreuse4 961, 150 241, 37 240, 37 240, 34 240, 41 0.0426 0.0886 0.631 0.2002 1.04 0.877 1.24 0.0438 0.252 0.862 0.06455 1.04 0.638 1.71 0.0198 0.262 0.94 0.02704 1.02 0.611 1.7 0.124 0.26 0.632 0.1993 1.13 0.681 1.88 PRS_PLINK_0.0199526231496888 FALSE 536.8 Dyspepsia and other specified disorders of function of stomach Both 636 5805 10 digestive chartreuse4 5805, 636 1452, 157 1451, 157 1451, 159 1451, 162 0.00413 0.043 0.923 0.03462 1 0.923 1.09 0.00697 0.119 0.953 0.02077 1.01 0.797 1.27 0.00542 0.121 0.964 0.01586 1.01 0.794 1.27 0.0226 0.123 0.855 0.06814 1.02 0.803 1.3 PRS_PLINK_0.0199526231496888 FALSE 537 Other disorders of stomach and duodenum Both 965 7874 10 digestive chartreuse4 7874, 965 1969, 226 1968, 259 1968, 247 1969, 232 0.0358 0.0351 0.308 0.5117 1.04 0.968 1.11 0.132 0.0969 0.174 0.7602 1.14 0.944 1.38 0.104 0.0992 0.295 0.5304 1.11 0.913 1.35 0.0317 0.104 0.76 0.119 1.03 0.842 1.26 PRS_PLINK_0.0199526231496888 FALSE 537.1 Lesions of stomach and duodenum Both 58 342 10 digestive chartreuse4 342, 58 86, 11 85, 14 85, 18 86, 15 0.201 0.139 0.148 0.8286 1.22 0.931 1.6 0.313 0.422 0.458 0.3395 1.37 0.599 3.13 0.479 0.414 0.247 0.6079 1.61 0.718 3.63 0.34 0.429 0.427 0.3692 1.41 0.607 3.26 PRS_PLINK_0.0199526231496888 FALSE 539 Bariatric surgery Both 385 4794 10 digestive chartreuse4 4794, 385 1198, 94 1198, 104 1198, 86 1199, 101 0.0401 0.0543 0.46 0.3368 1.04 0.936 1.16 0.122 0.148 0.411 0.3865 1.13 0.845 1.51 -0.0474 0.156 0.762 0.1182 0.954 0.702 1.3 0.103 0.154 0.505 0.2968 1.11 0.819 1.5 PRS_PLINK_0.0199526231496888 FALSE 540 Appendiceal conditions Both 173 1503 10 digestive chartreuse4 1503, 173 375, 64 376, 36 375, 34 376, 39 -0.192 0.0862 0.0258 1.589 0.825 0.697 0.977 -0.613 0.22 0.00533 2.274 0.542 0.352 0.834 -0.702 0.227 0.00196 2.707 0.496 0.318 0.773 -0.605 0.226 0.00736 2.133 0.546 0.351 0.85 PRS_PLINK_0.0199526231496888 FALSE 540.1 Appendicitis Both 160 1324 10 digestive chartreuse4 1324, 160 330, 61 331, 30 331, 32 331, 37 -0.198 0.0892 0.0262 1.582 0.82 0.688 0.977 -0.736 0.235 0.00178 2.75 0.479 0.302 0.76 -0.725 0.233 0.00185 2.733 0.484 0.307 0.764 -0.596 0.232 0.0102 1.991 0.551 0.35 0.868 PRS_PLINK_0.0199526231496888 FALSE 540.11 Acute appendicitis Both 135 1104 10 digestive chartreuse4 1104, 135 275, 46 276, 33 276, 26 276, 30 -0.178 0.096 0.0644 1.191 0.837 0.694 1.01 -0.372 0.243 0.125 0.9016 0.689 0.428 1.11 -0.622 0.26 0.0167 1.777 0.537 0.322 0.894 -0.468 0.258 0.0701 1.154 0.626 0.377 1.04 PRS_PLINK_0.0199526231496888 FALSE 550 Abdominal hernia Both 1593 10074 10 digestive chartreuse4 10074, 1593 2519, 428 2518, 386 2518, 403 2519, 375 -0.0199 0.0279 0.475 0.3234 0.98 0.928 1.04 -0.0864 0.0768 0.26 0.5846 0.917 0.789 1.07 -0.0439 0.077 0.568 0.2453 0.957 0.823 1.11 -0.112 0.0803 0.164 0.7864 0.894 0.764 1.05 PRS_PLINK_0.0199526231496888 FALSE 550.1 Inguinal hernia Both 380 3253 10 digestive chartreuse4 3253, 380 814, 109 813, 103 813, 86 813, 82 -0.142 0.0553 0.0104 1.982 0.868 0.779 0.967 -0.0744 0.146 0.61 0.2145 0.928 0.698 1.24 -0.243 0.155 0.117 0.9319 0.785 0.579 1.06 -0.288 0.161 0.0733 1.135 0.749 0.547 1.03 PRS_PLINK_0.0199526231496888 FALSE 550.2 Diaphragmatic hernia Both 630 6184 10 digestive chartreuse4 6184, 630 1546, 175 1546, 145 1546, 163 1546, 146 -0.0144 0.0428 0.737 0.1328 0.986 0.906 1.07 -0.167 0.118 0.158 0.8007 0.846 0.671 1.07 -0.0491 0.117 0.675 0.171 0.952 0.757 1.2 -0.176 0.124 0.154 0.8114 0.838 0.658 1.07 PRS_PLINK_0.0199526231496888 FALSE 550.3 Femoral hernia Both 41 282 10 digestive chartreuse4 282, 41 71, 14 70, 12 70, 8 71, 7 -0.281 0.161 0.0821 1.086 0.755 0.55 1.04 -0.0554 0.434 0.898 0.0466 0.946 0.404 2.21 -0.504 0.505 0.318 0.4977 0.604 0.224 1.62 -0.596 0.525 0.256 0.5917 0.551 0.197 1.54 PRS_PLINK_0.0199526231496888 TRUE 550.4 Umbilical hernia Both 319 3118 10 digestive chartreuse4 3118, 319 780, 86 779, 76 779, 71 780, 86 0.0199 0.0609 0.744 0.1286 1.02 0.905 1.15 -0.145 0.166 0.382 0.4175 0.865 0.626 1.2 -0.171 0.17 0.315 0.5011 0.843 0.604 1.18 0.0108 0.168 0.949 0.02278 1.01 0.727 1.41 PRS_PLINK_0.0199526231496888 FALSE 550.5 Ventral hernia Both 576 5278 10 digestive chartreuse4 5278, 576 1320, 146 1319, 127 1319, 149 1320, 153 0.0197 0.0451 0.662 0.1791 1.02 0.934 1.11 -0.149 0.127 0.24 0.6192 0.861 0.671 1.11 0.0411 0.124 0.741 0.1303 1.04 0.817 1.33 0.0237 0.126 0.851 0.07004 1.02 0.799 1.31 PRS_PLINK_0.0199526231496888 FALSE 550.6 Incisional hernia Both 344 3108 10 digestive chartreuse4 3108, 344 777, 95 777, 76 777, 80 777, 92 -0.0418 0.0577 0.469 0.3289 0.959 0.857 1.07 -0.218 0.161 0.178 0.7503 0.804 0.586 1.1 -0.154 0.161 0.339 0.4701 0.857 0.625 1.18 -0.0938 0.16 0.559 0.2525 0.91 0.665 1.25 PRS_PLINK_0.0199526231496888 FALSE 555 Inflammatory bowel disease and other gastroenteritis and colitis Both 571 4207 10 digestive chartreuse4 4207, 571 1052, 122 1052, 164 1051, 142 1052, 143 0.0854 0.0467 0.0674 1.171 1.09 0.994 1.19 0.313 0.128 0.0142 1.847 1.37 1.06 1.76 0.185 0.134 0.167 0.7768 1.2 0.925 1.56 0.154 0.138 0.264 0.5792 1.17 0.89 1.53 PRS_PLINK_0.0199526231496888 FALSE 555.1 Regional enteritis Both 351 2594 10 digestive chartreuse4 2594, 351 649, 81 648, 100 648, 90 649, 80 0.0459 0.0584 0.431 0.3653 1.05 0.934 1.17 0.249 0.16 0.12 0.9203 1.28 0.937 1.76 0.144 0.166 0.385 0.4144 1.16 0.834 1.6 -0.000458 0.175 0.998 0.0009074 1 0.709 1.41 PRS_PLINK_0.0199526231496888 FALSE 555.2 Ulcerative colitis Both 361 2578 10 digestive chartreuse4 2578, 361 645, 71 644, 101 644, 87 645, 102 0.142 0.0598 0.0172 1.766 1.15 1.03 1.3 0.35 0.165 0.0336 1.473 1.42 1.03 1.96 0.215 0.172 0.213 0.6709 1.24 0.884 1.74 0.316 0.172 0.0665 1.177 1.37 0.979 1.92 PRS_PLINK_0.0199526231496888 FALSE 555.21 Ulcerative colitis (chronic) Both 234 1560 10 digestive chartreuse4 1560, 234 390, 45 390, 70 390, 56 390, 63 0.131 0.0752 0.0819 1.087 1.14 0.984 1.32 0.444 0.203 0.0291 1.535 1.56 1.05 2.32 0.262 0.215 0.225 0.6484 1.3 0.852 1.98 0.306 0.217 0.159 0.799 1.36 0.887 2.08 PRS_PLINK_0.0199526231496888 FALSE 556 Ulceration of the lower GI tract Both 195 1399 10 digestive chartreuse4 1399, 195 350, 27 350, 48 349, 56 350, 64 0.279 0.0825 0.000736 3.133 1.32 1.12 1.55 0.56 0.25 0.0251 1.601 1.75 1.07 2.86 0.631 0.247 0.0105 1.98 1.88 1.16 3.05 0.808 0.247 0.0011 2.959 2.24 1.38 3.64 PRS_PLINK_0.0199526231496888 FALSE 556.1 Ulceration of intestine Both 173 1253 10 digestive chartreuse4 1253, 173 314, 23 313, 46 313, 48 313, 56 0.262 0.0864 0.00238 2.624 1.3 1.1 1.54 0.688 0.264 0.00922 2.035 1.99 1.19 3.34 0.643 0.264 0.0151 1.822 1.9 1.13 3.19 0.818 0.264 0.00197 2.706 2.27 1.35 3.8 PRS_PLINK_0.0199526231496888 FALSE 556.11 Angiodysplasia of intestine (without mention of hemorrhage) Both 54 349 10 digestive chartreuse4 349, 54 88, 7 87, 11 87, 15 87, 21 0.394 0.161 0.0142 1.847 1.48 1.08 2.03 0.473 0.495 0.339 0.4693 1.6 0.608 4.23 0.501 0.489 0.306 0.5141 1.65 0.632 4.31 0.937 0.478 0.0497 1.304 2.55 1 6.51 PRS_PLINK_0.0199526231496888 FALSE 557 Intestinal malabsorption (non-celiac) Both 549 5329 10 digestive chartreuse4 5329, 549 1333, 141 1332, 139 1332, 121 1332, 148 0.0677 0.0463 0.144 0.8416 1.07 0.977 1.17 -0.000146 0.126 0.999 0.0004017 1 0.781 1.28 -0.132 0.132 0.317 0.4985 0.876 0.676 1.14 0.056 0.13 0.667 0.1758 1.06 0.819 1.36 PRS_PLINK_0.0199526231496888 FALSE 557.1 Celiac disease Both 161 1354 10 digestive chartreuse4 1354, 161 339, 43 338, 39 338, 34 339, 45 0.0132 0.0841 0.875 0.05789 1.01 0.859 1.19 -0.0655 0.234 0.78 0.1079 0.937 0.592 1.48 -0.204 0.246 0.405 0.392 0.815 0.504 1.32 0.0831 0.237 0.726 0.1394 1.09 0.683 1.73 PRS_PLINK_0.0199526231496888 FALSE 558 Noninfectious gastroenteritis Both 1090 7308 10 digestive chartreuse4 7308, 1090 1827, 256 1827, 278 1827, 288 1827, 268 0.0609 0.0334 0.0681 1.167 1.06 0.995 1.13 0.088 0.0932 0.345 0.4625 1.09 0.91 1.31 0.111 0.0941 0.239 0.6224 1.12 0.929 1.34 0.0424 0.0982 0.666 0.1768 1.04 0.861 1.26 PRS_PLINK_0.0199526231496888 FALSE 559 Ileostomy status Both 312 2195 10 digestive chartreuse4 2195, 312 549, 63 549, 88 548, 69 549, 92 0.15 0.0626 0.0163 1.787 1.16 1.03 1.31 0.315 0.177 0.075 1.125 1.37 0.969 1.94 0.108 0.187 0.561 0.2507 1.11 0.773 1.61 0.317 0.181 0.0803 1.095 1.37 0.962 1.96 PRS_PLINK_0.0199526231496888 FALSE 560 Intestinal obstruction without mention of hernia Both 965 6253 10 digestive chartreuse4 6253, 965 1564, 230 1563, 229 1563, 239 1563, 266 0.0967 0.0354 0.00639 2.195 1.1 1.03 1.18 0.0114 0.101 0.91 0.04112 1.01 0.83 1.23 0.0739 0.102 0.467 0.3308 1.08 0.882 1.31 0.189 0.102 0.0647 1.189 1.21 0.989 1.47 PRS_PLINK_0.0199526231496888 FALSE 560.1 Paralytic ileus Both 502 3433 10 digestive chartreuse4 3433, 502 859, 111 858, 119 858, 132 858, 140 0.116 0.0486 0.0171 1.767 1.12 1.02 1.24 0.0687 0.141 0.625 0.2042 1.07 0.813 1.41 0.163 0.141 0.248 0.6064 1.18 0.893 1.55 0.227 0.142 0.108 0.965 1.26 0.951 1.66 PRS_PLINK_0.0199526231496888 FALSE 560.2 Impaction of intestine Both 148 1031 10 digestive chartreuse4 1031, 148 258, 40 258, 30 257, 41 258, 36 0.0367 0.0893 0.681 0.167 1.04 0.871 1.24 -0.277 0.255 0.276 0.5585 0.758 0.46 1.25 0.0862 0.244 0.724 0.1405 1.09 0.676 1.76 0.00419 0.256 0.987 0.005719 1 0.609 1.66 PRS_PLINK_0.0199526231496888 FALSE 560.3 Peritoneal or intestinal adhesions Both 85 627 10 digestive chartreuse4 627, 85 157, 23 157, 23 156, 21 157, 18 -0.0313 0.117 0.789 0.1032 0.969 0.771 1.22 0.0102 0.314 0.974 0.01139 1.01 0.546 1.87 -0.00237 0.326 0.994 0.002526 0.998 0.527 1.89 -0.419 0.345 0.224 0.6493 0.658 0.334 1.29 PRS_PLINK_0.0199526231496888 FALSE 560.4 Other intestinal obstruction Both 533 3964 10 digestive chartreuse4 3964, 533 991, 113 991, 126 991, 145 991, 149 0.142 0.0473 0.00276 2.559 1.15 1.05 1.26 0.129 0.138 0.35 0.4554 1.14 0.868 1.49 0.284 0.136 0.0369 1.433 1.33 1.02 1.73 0.286 0.139 0.0398 1.4 1.33 1.01 1.75 PRS_PLINK_0.0199526231496888 FALSE 561 Symptoms involving digestive system Both 810 6123 10 digestive chartreuse4 6123, 810 1531, 211 1531, 190 1530, 204 1531, 204 0.00476 0.0385 0.902 0.04503 1 0.932 1.08 -0.103 0.107 0.337 0.4725 0.902 0.732 1.11 -0.022 0.107 0.837 0.07743 0.978 0.793 1.21 -0.012 0.11 0.913 0.03965 0.988 0.797 1.23 PRS_PLINK_0.0199526231496888 FALSE 562 Diverticulosis and diverticulitis Both 1181 5530 10 digestive chartreuse4 5530, 1181 1383, 325 1382, 316 1382, 258 1383, 282 -0.0483 0.0336 0.151 0.8206 0.953 0.892 1.02 0.017 0.0912 0.852 0.06945 1.02 0.851 1.22 -0.213 0.0965 0.0269 1.57 0.808 0.669 0.976 -0.0796 0.0971 0.412 0.3849 0.923 0.763 1.12 PRS_PLINK_0.0199526231496888 FALSE 562.1 Diverticulosis Both 1170 5509 10 digestive chartreuse4 5509, 1170 1378, 323 1377, 311 1377, 256 1377, 280 -0.0493 0.0338 0.145 0.84 0.952 0.891 1.02 0.00615 0.0916 0.946 0.02388 1.01 0.841 1.2 -0.217 0.0968 0.0253 1.597 0.805 0.666 0.974 -0.0786 0.0974 0.42 0.3771 0.924 0.764 1.12 PRS_PLINK_0.0199526231496888 FALSE 562.2 Diverticulitis Both 309 3151 10 digestive chartreuse4 3151, 309 788, 71 788, 101 787, 66 788, 71 -0.0287 0.0606 0.636 0.1967 0.972 0.863 1.09 0.366 0.163 0.025 1.602 1.44 1.05 1.98 -0.0611 0.18 0.734 0.134 0.941 0.661 1.34 0.0213 0.182 0.907 0.04247 1.02 0.715 1.46 PRS_PLINK_0.0199526231496888 FALSE 564 Functional digestive disorders Both 3461 7780 10 digestive chartreuse4 7780, 3461 1945, 911 1945, 857 1945, 867 1945, 825 0.000602 0.0212 0.977 0.009946 1 0.96 1.04 -0.0568 0.0585 0.332 0.4792 0.945 0.843 1.06 -0.0316 0.059 0.592 0.2274 0.969 0.863 1.09 -0.0753 0.0613 0.219 0.66 0.927 0.822 1.05 PRS_PLINK_0.0199526231496888 FALSE 564.1 Irritable Bowel Syndrome Both 1138 6591 10 digestive chartreuse4 6591, 1138 1648, 288 1648, 286 1647, 288 1648, 276 0.0187 0.0333 0.575 0.2407 1.02 0.955 1.09 -0.000224 0.0916 0.998 0.0008464 1 0.835 1.2 0.0221 0.0927 0.811 0.09083 1.02 0.853 1.23 -0.0138 0.0963 0.886 0.0526 0.986 0.817 1.19 PRS_PLINK_0.0199526231496888 FALSE 564.9 Personal history of diseases of digestive system Both 853 6738 10 digestive chartreuse4 6738, 853 1685, 222 1684, 194 1684, 217 1685, 219 0.0137 0.0373 0.714 0.1464 1.01 0.942 1.09 -0.13 0.105 0.215 0.6679 0.878 0.716 1.08 -0.00393 0.104 0.97 0.01332 0.996 0.813 1.22 -0.0209 0.107 0.844 0.07343 0.979 0.794 1.21 PRS_PLINK_0.0199526231496888 FALSE 565 Anal and rectal conditions Both 936 7943 10 digestive chartreuse4 7943, 936 1986, 230 1986, 264 1985, 217 1986, 225 -0.0124 0.0354 0.725 0.1396 0.988 0.921 1.06 0.139 0.0959 0.149 0.8282 1.15 0.952 1.39 -0.0275 0.101 0.786 0.1046 0.973 0.797 1.19 -0.0288 0.103 0.781 0.1073 0.972 0.793 1.19 PRS_PLINK_0.0199526231496888 FALSE 565.1 Anal and rectal polyp Both 274 2640 10 digestive chartreuse4 2640, 274 660, 69 660, 76 660, 65 660, 64 -0.0334 0.0646 0.605 0.2183 0.967 0.852 1.1 0.0561 0.175 0.749 0.1257 1.06 0.75 1.49 -0.0894 0.183 0.624 0.2045 0.914 0.639 1.31 -0.142 0.189 0.451 0.3454 0.867 0.599 1.26 PRS_PLINK_0.0199526231496888 FALSE 567 Peritonitis and retroperitoneal infections Both 430 3253 10 digestive chartreuse4 3253, 430 814, 95 813, 110 813, 111 813, 114 0.111 0.0525 0.0347 1.46 1.12 1.01 1.24 0.166 0.149 0.264 0.579 1.18 0.882 1.58 0.161 0.15 0.281 0.5507 1.18 0.876 1.58 0.178 0.153 0.246 0.6096 1.19 0.885 1.61 PRS_PLINK_0.0199526231496888 FALSE 568 Other disorders of peritoneum Both 515 4125 10 digestive chartreuse4 4125, 515 1032, 107 1031, 146 1031, 119 1031, 143 0.114 0.0483 0.0188 1.726 1.12 1.02 1.23 0.327 0.135 0.0155 1.809 1.39 1.06 1.81 0.109 0.142 0.445 0.3513 1.11 0.843 1.47 0.321 0.141 0.023 1.639 1.38 1.05 1.82 PRS_PLINK_0.0199526231496888 FALSE 568.1 Peritoneal adhesions (postoperative) (postinfection) Both 370 3025 10 digestive chartreuse4 3025, 370 757, 72 756, 105 756, 79 756, 114 0.15 0.057 0.00846 2.072 1.16 1.04 1.3 0.401 0.162 0.0131 1.883 1.49 1.09 2.05 0.12 0.173 0.488 0.3115 1.13 0.803 1.58 0.451 0.165 0.00619 2.209 1.57 1.14 2.17 PRS_PLINK_0.0199526231496888 FALSE 569 Other disorders of intestine Both 2118 9677 10 digestive chartreuse4 9677, 2118 2420, 520 2419, 579 2419, 519 2419, 499 0.0111 0.0249 0.654 0.1841 1.01 0.963 1.06 0.143 0.0682 0.0357 1.447 1.15 1.01 1.32 0.0186 0.0706 0.792 0.101 1.02 0.887 1.17 0.00538 0.073 0.941 0.02628 1.01 0.871 1.16 PRS_PLINK_0.0199526231496888 FALSE 569.1 Toxic gastroenteritis and colitis Both 90 809 10 digestive chartreuse4 809, 90 203, 21 202, 30 202, 26 202, 13 -0.134 0.11 0.222 0.6542 0.874 0.705 1.08 0.281 0.3 0.348 0.458 1.32 0.736 2.39 0.0219 0.318 0.945 0.02449 1.02 0.548 1.91 -0.582 0.376 0.121 0.9166 0.559 0.268 1.17 PRS_PLINK_0.0199526231496888 FALSE 569.2 Gastrointestinal complications Both 442 3619 10 digestive chartreuse4 3619, 442 905, 97 905, 107 904, 108 905, 130 0.159 0.0519 0.00226 2.647 1.17 1.06 1.3 0.113 0.148 0.447 0.3495 1.12 0.837 1.5 0.104 0.15 0.486 0.313 1.11 0.828 1.49 0.281 0.148 0.0583 1.234 1.32 0.99 1.77 PRS_PLINK_0.0199526231496888 FALSE 571 Chronic liver disease and cirrhosis Both 1140 8542 10 digestive chartreuse4 8542, 1140 2136, 265 2135, 273 2135, 285 2136, 316 0.131 0.0325 5.66e-05 4.247 1.14 1.07 1.21 0.0414 0.0924 0.654 0.1844 1.04 0.87 1.25 0.109 0.0929 0.239 0.622 1.12 0.93 1.34 0.231 0.0935 0.0135 1.869 1.26 1.05 1.51 PRS_PLINK_0.0199526231496888 FALSE 571.5 Other chronic nonalcoholic liver disease Both 1045 8411 10 digestive chartreuse4 8411, 1045 2103, 244 2103, 254 2102, 256 2103, 290 0.123 0.0338 0.000275 3.56 1.13 1.06 1.21 0.0587 0.0956 0.539 0.2684 1.06 0.879 1.28 0.0953 0.0968 0.325 0.4883 1.1 0.91 1.33 0.232 0.0971 0.0167 1.776 1.26 1.04 1.53 PRS_PLINK_0.0199526231496888 FALSE 571.51 Cirrhosis of liver without mention of alcohol Both 305 2275 10 digestive chartreuse4 2275, 305 569, 55 569, 84 568, 66 569, 100 0.256 0.063 4.94e-05 4.306 1.29 1.14 1.46 0.417 0.183 0.0225 1.647 1.52 1.06 2.17 0.211 0.192 0.273 0.5643 1.23 0.847 1.8 0.589 0.186 0.00158 2.803 1.8 1.25 2.6 PRS_PLINK_0.0199526231496888 FALSE 571.6 Primary biliary cirrhosis Both 64 416 10 digestive chartreuse4 416, 64 104, 10 104, 22 104, 12 104, 20 0.192 0.14 0.171 0.7667 1.21 0.921 1.59 0.798 0.397 0.0445 1.351 2.22 1.02 4.84 0.218 0.446 0.625 0.2043 1.24 0.519 2.98 0.799 0.436 0.0672 1.173 2.22 0.945 5.23 PRS_PLINK_0.0199526231496888 FALSE 571.8 Liver abscess and sequelae of chronic liver disease Both 341 2097 10 digestive chartreuse4 2097, 341 525, 72 524, 80 524, 76 524, 113 0.234 0.0595 8.28e-05 4.082 1.26 1.12 1.42 0.128 0.174 0.464 0.3338 1.14 0.808 1.6 0.0731 0.178 0.682 0.1664 1.08 0.759 1.53 0.47 0.17 0.0058 2.237 1.6 1.15 2.23 PRS_PLINK_0.0199526231496888 FALSE 571.81 Portal hypertension Both 211 1230 10 digestive chartreuse4 1230, 211 308, 41 307, 57 307, 50 308, 63 0.2 0.0747 0.00754 2.123 1.22 1.05 1.41 0.322 0.218 0.14 0.8541 1.38 0.9 2.12 0.171 0.227 0.45 0.3468 1.19 0.761 1.85 0.425 0.224 0.0582 1.235 1.53 0.985 2.37 PRS_PLINK_0.0199526231496888 FALSE 572 Ascites (non malignant) Both 800 5577 10 digestive chartreuse4 5577, 800 1395, 184 1394, 187 1394, 193 1394, 236 0.164 0.039 2.57e-05 4.59 1.18 1.09 1.27 0.0285 0.111 0.797 0.09837 1.03 0.828 1.28 0.0862 0.112 0.439 0.3571 1.09 0.876 1.36 0.267 0.11 0.0153 1.816 1.31 1.05 1.62 PRS_PLINK_0.0199526231496888 FALSE 573 Other disorders of liver Both 1459 8998 10 digestive chartreuse4 8998, 1459 2250, 365 2249, 352 2249, 358 2250, 383 0.0897 0.0293 0.00219 2.66 1.09 1.03 1.16 -0.00989 0.0817 0.904 0.04401 0.99 0.844 1.16 0.0268 0.0827 0.746 0.1275 1.03 0.874 1.21 0.118 0.084 0.161 0.7944 1.13 0.954 1.33 PRS_PLINK_0.0199526231496888 FALSE 573.1 Chronic passive congestion of liver Both 88 321 10 digestive chartreuse4 321, 88 81, 21 80, 20 80, 21 80, 25 0.14 0.115 0.223 0.6524 1.15 0.918 1.44 0.127 0.365 0.727 0.1384 1.14 0.555 2.32 0.311 0.373 0.405 0.3924 1.36 0.656 2.84 0.276 0.35 0.431 0.366 1.32 0.664 2.61 PRS_PLINK_0.0199526231496888 FALSE 573.2 Liver replaced by transplant Both 67 626 10 digestive chartreuse4 626, 67 157, 17 156, 16 156, 14 157, 20 0.0365 0.134 0.785 0.1052 1.04 0.798 1.35 -0.0383 0.36 0.915 0.03849 0.962 0.475 1.95 -0.168 0.38 0.659 0.1809 0.846 0.401 1.78 0.00816 0.361 0.982 0.007905 1.01 0.497 2.05 PRS_PLINK_0.0199526231496888 FALSE 573.3 Hepatomegaly Both 118 1290 10 digestive chartreuse4 1290, 118 323, 18 322, 27 322, 35 323, 38 0.331 0.0992 0.00084 3.076 1.39 1.15 1.69 0.433 0.302 0.151 0.8209 1.54 0.854 2.79 0.762 0.295 0.00983 2.007 2.14 1.2 3.82 0.841 0.303 0.00554 2.257 2.32 1.28 4.2 PRS_PLINK_0.0199526231496888 FALSE 573.4 Acute and subacute necrosis of liver Both 141 753 10 digestive chartreuse4 753, 141 189, 24 188, 30 188, 36 188, 51 0.435 0.0998 1.33e-05 4.877 1.54 1.27 1.88 0.276 0.296 0.351 0.4541 1.32 0.738 2.35 0.462 0.282 0.101 0.9956 1.59 0.914 2.76 0.934 0.287 0.00114 2.944 2.54 1.45 4.47 PRS_PLINK_0.0199526231496888 FALSE 573.5 Jaundice (not of newborn) Both 320 2171 10 digestive chartreuse4 2171, 320 543, 83 543, 78 542, 68 543, 91 0.0556 0.0617 0.368 0.4346 1.06 0.937 1.19 -0.0676 0.17 0.69 0.161 0.935 0.67 1.3 -0.178 0.179 0.32 0.4955 0.837 0.589 1.19 0.0785 0.174 0.652 0.1856 1.08 0.769 1.52 PRS_PLINK_0.0199526231496888 FALSE 573.6 Nonspecific elevation of levels of transaminase or lactic acid dehydrogenase [LDH] Both 794 6429 10 digestive chartreuse4 6429, 794 1608, 194 1607, 190 1607, 207 1607, 202 0.0425 0.0388 0.274 0.5627 1.04 0.967 1.13 -0.0386 0.109 0.722 0.1413 0.962 0.778 1.19 0.0713 0.108 0.511 0.292 1.07 0.868 1.33 0.0531 0.112 0.636 0.1965 1.05 0.846 1.31 PRS_PLINK_0.0199526231496888 FALSE 573.7 Abnormal results of function study of liver Both 794 6778 10 digestive chartreuse4 6778, 794 1695, 212 1694, 196 1694, 195 1695, 191 0.02 0.0387 0.606 0.2175 1.02 0.946 1.1 -0.0901 0.106 0.394 0.4042 0.914 0.743 1.12 -0.0617 0.107 0.565 0.2476 0.94 0.762 1.16 -0.0838 0.111 0.45 0.3469 0.92 0.74 1.14 PRS_PLINK_0.0199526231496888 FALSE 573.9 Abnormal serum enzyme levels Both 1270 8986 10 digestive chartreuse4 8986, 1270 2247, 309 2246, 303 2246, 332 2247, 325 0.0426 0.031 0.17 0.769 1.04 0.982 1.11 -0.00122 0.0871 0.989 0.004897 0.999 0.842 1.18 0.0864 0.0867 0.319 0.4966 1.09 0.92 1.29 0.0811 0.0894 0.365 0.4381 1.08 0.91 1.29 PRS_PLINK_0.0199526231496888 FALSE 574 Cholelithiasis and cholecystitis Both 892 8534 10 digestive chartreuse4 8534, 892 2134, 214 2133, 211 2133, 240 2134, 226 0.0501 0.0361 0.165 0.7812 1.05 0.98 1.13 -0.0074 0.102 0.942 0.0259 0.993 0.813 1.21 0.121 0.101 0.23 0.6376 1.13 0.926 1.37 0.0647 0.105 0.538 0.269 1.07 0.868 1.31 PRS_PLINK_0.0199526231496888 FALSE 574.1 Cholelithiasis Both 808 8047 10 digestive chartreuse4 8047, 808 2012, 196 2012, 186 2011, 213 2012, 212 0.0495 0.0378 0.19 0.7211 1.05 0.976 1.13 -0.0462 0.107 0.667 0.1762 0.955 0.774 1.18 0.0826 0.106 0.434 0.362 1.09 0.883 1.34 0.0818 0.109 0.453 0.344 1.09 0.877 1.34 PRS_PLINK_0.0199526231496888 FALSE 574.11 Cholelithiasis with acute cholecystitis Both 105 846 10 digestive chartreuse4 846, 105 212, 24 211, 25 211, 28 212, 28 0.0661 0.106 0.532 0.2739 1.07 0.868 1.31 0.0612 0.299 0.837 0.07702 1.06 0.592 1.91 0.175 0.297 0.555 0.2561 1.19 0.666 2.13 0.181 0.313 0.563 0.2495 1.2 0.649 2.22 PRS_PLINK_0.0199526231496888 FALSE 574.12 Cholelithiasis with other cholecystitis Both 142 1555 10 digestive chartreuse4 1555, 142 389, 30 389, 41 388, 39 389, 32 0.0251 0.0892 0.778 0.1088 1.03 0.861 1.22 0.378 0.251 0.131 0.8832 1.46 0.894 2.39 0.182 0.252 0.47 0.3279 1.2 0.732 1.97 0.162 0.276 0.557 0.2542 1.18 0.685 2.02 PRS_PLINK_0.0199526231496888 FALSE 574.2 Calculus of bile duct Both 245 2425 10 digestive chartreuse4 2425, 245 607, 70 606, 59 606, 56 606, 59 -0.045 0.0679 0.507 0.295 0.956 0.837 1.09 -0.167 0.185 0.367 0.4355 0.847 0.59 1.22 -0.28 0.19 0.141 0.8499 0.756 0.521 1.1 -0.142 0.194 0.464 0.3331 0.868 0.594 1.27 PRS_PLINK_0.0199526231496888 FALSE 574.3 Cholecystitis without cholelithiasis Both 238 2125 10 digestive chartreuse4 2125, 238 532, 47 531, 67 531, 65 531, 59 0.0643 0.0705 0.362 0.4417 1.07 0.929 1.22 0.357 0.199 0.0729 1.137 1.43 0.967 2.11 0.325 0.202 0.109 0.9636 1.38 0.93 2.06 0.249 0.213 0.243 0.614 1.28 0.844 1.95 PRS_PLINK_0.0199526231496888 FALSE 575 Other biliary tract disease Both 672 5996 10 digestive chartreuse4 5996, 672 1499, 160 1499, 168 1499, 162 1499, 181 0.0561 0.0416 0.178 0.7499 1.06 0.975 1.15 0.039 0.116 0.738 0.1321 1.04 0.828 1.31 0.0271 0.119 0.819 0.0867 1.03 0.814 1.3 0.139 0.119 0.244 0.6128 1.15 0.91 1.45 PRS_PLINK_0.0199526231496888 FALSE 575.1 Cholangitis Both 120 801 10 digestive chartreuse4 801, 120 201, 31 200, 28 200, 24 200, 37 0.0885 0.104 0.394 0.4041 1.09 0.891 1.34 -0.0858 0.279 0.759 0.12 0.918 0.531 1.59 -0.253 0.297 0.395 0.4036 0.776 0.433 1.39 0.134 0.272 0.621 0.2071 1.14 0.672 1.95 PRS_PLINK_0.0199526231496888 FALSE 575.2 Obstruction of bile duct Both 203 1444 10 digestive chartreuse4 1444, 203 361, 51 361, 44 361, 45 361, 62 0.117 0.0782 0.134 0.8729 1.12 0.965 1.31 -0.151 0.216 0.486 0.3136 0.86 0.563 1.31 -0.114 0.219 0.603 0.2196 0.892 0.581 1.37 0.216 0.211 0.306 0.5143 1.24 0.82 1.88 PRS_PLINK_0.0199526231496888 FALSE 575.6 Cholesterolosis of gallbladder Both 71 610 10 digestive chartreuse4 610, 71 153, 21 152, 20 152, 16 153, 14 -0.0805 0.127 0.527 0.2782 0.923 0.719 1.18 -0.002 0.337 0.995 0.002061 0.998 0.515 1.93 -0.162 0.36 0.652 0.1854 0.851 0.42 1.72 -0.55 0.393 0.162 0.7902 0.577 0.267 1.25 PRS_PLINK_0.0199526231496888 FALSE 575.7 Other disorders of gallbladder Both 273 2632 10 digestive chartreuse4 2632, 273 658, 65 658, 73 658, 71 658, 64 0.0312 0.0658 0.635 0.1972 1.03 0.907 1.17 0.13 0.179 0.467 0.3303 1.14 0.802 1.62 0.144 0.184 0.434 0.3629 1.15 0.805 1.66 0.0639 0.195 0.743 0.1289 1.07 0.727 1.56 PRS_PLINK_0.0199526231496888 FALSE 575.8 Other disorders of biliary tract Both 362 2835 10 digestive chartreuse4 2835, 362 709, 86 709, 82 708, 91 709, 102 0.0946 0.0572 0.0984 1.007 1.1 0.983 1.23 -0.054 0.162 0.74 0.1309 0.947 0.689 1.3 0.0774 0.161 0.63 0.2005 1.08 0.789 1.48 0.192 0.161 0.234 0.6316 1.21 0.884 1.66 PRS_PLINK_0.0199526231496888 FALSE 575.9 Nonspecific abnormal findings on radiological and other examination of biliary tract Both 72 649 10 digestive chartreuse4 649, 72 163, 13 162, 21 162, 17 162, 21 0.108 0.121 0.375 0.4261 1.11 0.878 1.41 0.416 0.36 0.249 0.604 1.52 0.748 3.07 0.359 0.37 0.332 0.4785 1.43 0.693 2.96 0.478 0.372 0.199 0.7008 1.61 0.777 3.35 PRS_PLINK_0.0199526231496888 FALSE 577 Diseases of pancreas Both 579 5355 10 digestive chartreuse4 5355, 579 1339, 147 1339, 142 1338, 131 1339, 158 0.0629 0.0449 0.161 0.7927 1.06 0.975 1.16 -0.0369 0.124 0.766 0.1157 0.964 0.756 1.23 -0.0952 0.128 0.456 0.3406 0.909 0.708 1.17 0.0758 0.126 0.548 0.2614 1.08 0.843 1.38 PRS_PLINK_0.0199526231496888 FALSE 577.1 Acute pancreatitis Both 319 3093 10 digestive chartreuse4 3093, 319 774, 65 773, 85 773, 79 773, 89 0.127 0.0601 0.0353 1.453 1.13 1.01 1.28 0.283 0.172 0.0992 1.004 1.33 0.948 1.86 0.22 0.177 0.214 0.6691 1.25 0.881 1.76 0.337 0.177 0.057 1.244 1.4 0.99 1.98 PRS_PLINK_0.0199526231496888 FALSE 577.2 Chronic pancreatitis Both 136 1186 10 digestive chartreuse4 1186, 136 297, 28 296, 38 296, 37 297, 33 0.0994 0.0931 0.285 0.5444 1.1 0.92 1.33 0.36 0.262 0.169 0.7713 1.43 0.858 2.4 0.218 0.269 0.418 0.3792 1.24 0.734 2.11 0.153 0.283 0.588 0.2309 1.17 0.67 2.03 PRS_PLINK_0.0199526231496888 FALSE 577.3 Cyst and pseudocyst of pancreas Both 138 1173 10 digestive chartreuse4 1173, 138 294, 40 293, 35 293, 28 293, 35 -0.0301 0.0918 0.743 0.1293 0.97 0.811 1.16 -0.171 0.243 0.482 0.3167 0.843 0.524 1.36 -0.384 0.263 0.144 0.8423 0.681 0.407 1.14 -0.0914 0.258 0.723 0.1409 0.913 0.551 1.51 PRS_PLINK_0.0199526231496888 FALSE 578 Gastrointestinal hemorrhage Both 1358 9907 10 digestive chartreuse4 9907, 1358 2477, 306 2477, 364 2476, 333 2477, 354 0.0506 0.0298 0.0902 1.045 1.05 0.992 1.12 0.174 0.0831 0.0363 1.44 1.19 1.01 1.4 0.0834 0.0858 0.331 0.4803 1.09 0.919 1.29 0.165 0.0873 0.0586 1.232 1.18 0.994 1.4 PRS_PLINK_0.0199526231496888 FALSE 578.1 Hematemesis Both 157 1218 10 digestive chartreuse4 1218, 157 305, 32 304, 38 304, 48 305, 38 0.109 0.0855 0.201 0.6964 1.12 0.943 1.32 0.149 0.251 0.553 0.2571 1.16 0.71 1.9 0.391 0.244 0.109 0.9626 1.48 0.916 2.39 0.0467 0.261 0.858 0.06657 1.05 0.629 1.75 PRS_PLINK_0.0199526231496888 FALSE 578.2 Blood in stool Both 817 6616 10 digestive chartreuse4 6616, 817 1654, 189 1654, 218 1654, 203 1654, 206 0.0218 0.038 0.566 0.2472 1.02 0.949 1.1 0.137 0.106 0.194 0.7125 1.15 0.933 1.41 0.0417 0.108 0.7 0.1548 1.04 0.843 1.29 0.0728 0.111 0.512 0.291 1.08 0.865 1.34 PRS_PLINK_0.0199526231496888 FALSE 578.8 Hemorrhage of rectum and anus Both 668 5905 10 digestive chartreuse4 5905, 668 1477, 156 1476, 173 1476, 168 1476, 171 0.0544 0.0422 0.198 0.7039 1.06 0.972 1.15 0.108 0.116 0.354 0.4505 1.11 0.887 1.4 0.117 0.118 0.324 0.4895 1.12 0.891 1.42 0.0835 0.122 0.494 0.306 1.09 0.856 1.38 PRS_PLINK_0.0199526231496888 FALSE 578.9 Hemorrhage of gastrointestinal tract Both 482 3427 10 digestive chartreuse4 3427, 482 857, 90 857, 138 856, 123 857, 130 0.115 0.0503 0.0221 1.655 1.12 1.02 1.24 0.422 0.144 0.00336 2.473 1.52 1.15 2.02 0.315 0.148 0.034 1.468 1.37 1.02 1.83 0.351 0.152 0.0211 1.676 1.42 1.05 1.91 PRS_PLINK_0.0199526231496888 FALSE 579 Other symptoms involving abdomen and pelvis Both 1337 9171 10 digestive chartreuse4 9171, 1337 2293, 322 2293, 325 2292, 336 2293, 354 0.0753 0.0302 0.0127 1.897 1.08 1.02 1.14 0.0227 0.0848 0.789 0.1031 1.02 0.866 1.21 0.056 0.0853 0.511 0.2915 1.06 0.895 1.25 0.151 0.0868 0.0827 1.083 1.16 0.981 1.38 PRS_PLINK_0.0199526231496888 FALSE 579.2 Splenomegaly Both 220 1824 10 digestive chartreuse4 1824, 220 456, 42 456, 56 456, 54 456, 68 0.179 0.0724 0.0134 1.871 1.2 1.04 1.38 0.318 0.214 0.137 0.8626 1.37 0.904 2.09 0.304 0.218 0.163 0.7888 1.36 0.884 2.08 0.492 0.215 0.0222 1.654 1.64 1.07 2.5 PRS_PLINK_0.0199526231496888 FALSE 579.8 Nonspecific abnormal findings in stool contents Both 398 3194 10 digestive chartreuse4 3194, 398 799, 104 798, 102 798, 100 799, 91 -0.0376 0.0546 0.49 0.3096 0.963 0.865 1.07 -0.0163 0.148 0.913 0.03977 0.984 0.736 1.32 -0.0235 0.151 0.876 0.05739 0.977 0.727 1.31 -0.18 0.158 0.254 0.5955 0.835 0.612 1.14 PRS_PLINK_0.0199526231496888 FALSE 580 Nephritis; nephrosis; renal sclerosis Both 333 3830 11 genitourinary black 3830, 333 958, 75 957, 61 957, 91 958, 105 0.188 0.0596 0.00162 2.79 1.21 1.07 1.36 -0.202 0.177 0.256 0.5926 0.817 0.577 1.16 0.185 0.166 0.264 0.5784 1.2 0.87 1.66 0.422 0.165 0.0107 1.97 1.52 1.1 2.11 PRS_PLINK_0.0199526231496888 FALSE 580.1 Glomerulonephritis Both 71 952 11 genitourinary black 952, 71 238, 12 238, 12 238, 24 238, 23 0.226 0.121 0.0619 1.208 1.25 0.989 1.59 0.0823 0.393 0.834 0.07883 1.09 0.503 2.34 0.584 0.36 0.105 0.9798 1.79 0.886 3.63 0.661 0.368 0.072 1.143 1.94 0.943 3.98 PRS_PLINK_0.0199526231496888 FALSE 580.11 Proliferative glomerulonephritis Both 24 364 11 genitourinary black 364, 24 91, 3 91, 6 91, 6 91, 9 0.425 0.216 0.0492 1.308 1.53 1 2.34 0.769 0.647 0.235 0.6294 2.16 0.607 7.67 0.54 0.644 0.402 0.3956 1.72 0.485 6.06 1.4 0.667 0.0358 1.446 4.05 1.1 15 PRS_PLINK_0.0199526231496888 TRUE 580.12 Non-proliferative glomerulonephritis Both 22 282 11 genitourinary black 282, 22 71, 3 70, 4 70, 4 71, 11 0.522 0.226 0.021 1.677 1.68 1.08 2.62 0.198 0.677 0.77 0.1133 1.22 0.323 4.59 0.4 0.677 0.555 0.2559 1.49 0.396 5.63 1.15 0.633 0.0688 1.162 3.17 0.915 11 PRS_PLINK_0.0199526231496888 TRUE 580.13 Acute glomerulonephritis, NOS Both 17 144 11 genitourinary black 144, 17 36, 6 36, 1 36, 5 36, 5 0.0872 0.229 0.703 0.1528 1.09 0.696 1.71 -1.46 0.894 0.102 0.9896 0.232 0.0403 1.34 -0.237 0.644 0.713 0.1469 0.789 0.223 2.79 0.00626 0.666 0.992 0.00327 1.01 0.273 3.72 PRS_PLINK_0.0199526231496888 TRUE 580.14 Chronic glomerulonephritis, NOS Both 44 682 11 genitourinary black 682, 44 171, 7 170, 6 170, 17 171, 14 0.219 0.15 0.146 0.8366 1.24 0.927 1.67 -0.0931 0.494 0.85 0.07035 0.911 0.346 2.4 0.732 0.441 0.0967 1.015 2.08 0.877 4.93 0.53 0.462 0.251 0.6003 1.7 0.687 4.2 PRS_PLINK_0.0199526231496888 TRUE 580.2 Nephrotic syndrome without mention of glomerulonephritis Both 41 568 11 genitourinary black 568, 41 142, 9 142, 8 142, 11 142, 13 0.27 0.165 0.103 0.9874 1.31 0.947 1.81 -0.13 0.467 0.781 0.1074 0.878 0.352 2.19 0.256 0.454 0.573 0.242 1.29 0.531 3.14 0.273 0.455 0.548 0.2613 1.31 0.539 3.21 PRS_PLINK_0.0199526231496888 TRUE 580.3 Nephritis and nephropathy without mention of glomerulonephritis Both 226 2899 11 genitourinary black 2899, 226 725, 50 725, 43 724, 57 725, 75 0.218 0.072 0.00247 2.608 1.24 1.08 1.43 -0.152 0.213 0.476 0.3228 0.859 0.566 1.3 0.134 0.205 0.512 0.291 1.14 0.766 1.71 0.546 0.199 0.00593 2.227 1.73 1.17 2.55 PRS_PLINK_0.0199526231496888 FALSE 580.31 Nephritis and nephropathy in diseases classified elsewhere Both 106 1668 11 genitourinary black 1668, 106 417, 26 417, 21 417, 26 417, 32 0.128 0.104 0.216 0.665 1.14 0.928 1.39 -0.221 0.296 0.456 0.3413 0.802 0.449 1.43 -0.0102 0.288 0.972 0.01248 0.99 0.563 1.74 0.301 0.285 0.291 0.5356 1.35 0.772 2.36 PRS_PLINK_0.0199526231496888 FALSE 580.32 Nephritis and nephropathy with pathological lesion Both 137 1647 11 genitourinary black 1647, 137 412, 29 412, 24 411, 30 412, 54 0.271 0.094 0.004 2.398 1.31 1.09 1.58 -0.143 0.277 0.607 0.2166 0.867 0.504 1.49 0.0222 0.269 0.934 0.0295 1.02 0.603 1.73 0.703 0.249 0.00476 2.322 2.02 1.24 3.29 PRS_PLINK_0.0199526231496888 FALSE 580.4 Renal sclerosis, NOS Both 76 822 11 genitourinary black 822, 76 206, 16 205, 13 205, 22 206, 25 0.176 0.124 0.157 0.8043 1.19 0.935 1.52 -0.268 0.368 0.466 0.3315 0.765 0.371 1.57 0.259 0.335 0.439 0.3579 1.3 0.673 2.5 0.361 0.343 0.293 0.5331 1.43 0.732 2.81 PRS_PLINK_0.0199526231496888 FALSE 585 Renal failure Both 1706 8696 11 genitourinary black 8696, 1706 2174, 364 2174, 410 2174, 445 2174, 487 0.184 0.0286 1.09e-10 9.964 1.2 1.14 1.27 0.151 0.0812 0.0635 1.197 1.16 0.992 1.36 0.231 0.0814 0.00451 2.346 1.26 1.07 1.48 0.408 0.0829 8.34e-07 6.079 1.5 1.28 1.77 PRS_PLINK_0.0199526231496888 FALSE 585.1 Acute renal failure Both 1114 6489 11 genitourinary black 6489, 1114 1623, 213 1622, 278 1622, 289 1622, 334 0.239 0.0343 3.47e-12 11.46 1.27 1.19 1.36 0.293 0.0997 0.00328 2.484 1.34 1.1 1.63 0.304 0.1 0.00246 2.608 1.36 1.11 1.65 0.526 0.101 2.14e-07 6.67 1.69 1.39 2.07 PRS_PLINK_0.0199526231496888 FALSE 585.2 Renal failure NOS Both 206 1793 11 genitourinary black 1793, 206 449, 44 448, 52 448, 48 448, 62 0.197 0.0766 0.00999 2 1.22 1.05 1.42 0.174 0.214 0.415 0.3823 1.19 0.783 1.81 0.156 0.222 0.483 0.3158 1.17 0.756 1.8 0.4 0.216 0.0647 1.189 1.49 0.976 2.28 PRS_PLINK_0.0199526231496888 FALSE 585.3 Chronic renal failure [CKD] Both 1164 7456 11 genitourinary black 7456, 1164 1864, 248 1864, 262 1864, 307 1864, 347 0.204 0.0337 1.47e-09 8.832 1.23 1.15 1.31 0.0974 0.097 0.315 0.5013 1.1 0.911 1.33 0.24 0.0956 0.0121 1.916 1.27 1.05 1.53 0.464 0.0969 1.66e-06 5.779 1.59 1.32 1.92 PRS_PLINK_0.0199526231496888 FALSE 585.31 Renal dialysis Both 143 1720 11 genitourinary black 1720, 143 430, 30 430, 35 430, 41 430, 37 0.158 0.0889 0.0747 1.127 1.17 0.984 1.39 0.0925 0.257 0.718 0.1436 1.1 0.663 1.81 0.307 0.25 0.219 0.6588 1.36 0.833 2.22 0.249 0.262 0.342 0.4666 1.28 0.768 2.14 PRS_PLINK_0.0199526231496888 FALSE 585.32 End stage renal disease Both 167 2291 11 genitourinary black 2291, 167 573, 35 573, 38 572, 45 573, 49 0.213 0.0818 0.00917 2.038 1.24 1.05 1.45 0.0864 0.239 0.718 0.1438 1.09 0.682 1.74 0.258 0.232 0.267 0.5742 1.29 0.821 2.04 0.437 0.237 0.0659 1.181 1.55 0.972 2.47 PRS_PLINK_0.0199526231496888 FALSE 585.33 Chronic Kidney Disease, Stage III Both 613 4520 11 genitourinary black 4520, 613 1130, 128 1130, 129 1130, 160 1130, 196 0.251 0.0458 4.28e-08 7.369 1.29 1.17 1.41 0.0616 0.134 0.647 0.1892 1.06 0.817 1.38 0.261 0.131 0.0467 1.331 1.3 1 1.68 0.555 0.13 1.98e-05 4.704 1.74 1.35 2.25 PRS_PLINK_0.0199526231496888 FALSE 585.34 Chronic Kidney Disease, Stage IV Both 130 1883 11 genitourinary black 1883, 130 471, 25 471, 32 470, 26 471, 47 0.243 0.093 0.00884 2.053 1.28 1.06 1.53 0.223 0.268 0.405 0.3925 1.25 0.74 2.11 0.0285 0.282 0.92 0.03641 1.03 0.592 1.79 0.653 0.262 0.0128 1.892 1.92 1.15 3.21 PRS_PLINK_0.0199526231496888 FALSE 585.4 Chronic kidney disease, Stage I or II Both 269 2333 11 genitourinary black 2333, 269 584, 59 583, 57 583, 54 583, 99 0.256 0.0665 0.000117 3.932 1.29 1.13 1.47 0.000439 0.194 0.998 0.0007857 1 0.685 1.46 -0.0852 0.2 0.669 0.1744 0.918 0.621 1.36 0.516 0.184 0.00514 2.289 1.67 1.17 2.4 PRS_PLINK_0.0199526231496888 FALSE 586 Other disorders of the kidney and ureters Both 1737 9646 11 genitourinary black 9646, 1737 2412, 426 2411, 425 2411, 410 2412, 476 0.0931 0.0274 0.000684 3.165 1.1 1.04 1.16 0.0346 0.076 0.649 0.1878 1.04 0.892 1.2 -0.00555 0.0777 0.943 0.02548 0.994 0.854 1.16 0.206 0.0779 0.00825 2.084 1.23 1.05 1.43 PRS_PLINK_0.0199526231496888 FALSE 586.1 Anatomical abnormatilies of kidney and ureters Both 114 1018 11 genitourinary black 1018, 114 255, 26 254, 31 254, 24 255, 33 0.0733 0.0995 0.461 0.3362 1.08 0.885 1.31 0.184 0.275 0.503 0.2982 1.2 0.701 2.06 -0.0371 0.291 0.899 0.04639 0.964 0.544 1.71 0.329 0.279 0.24 0.6205 1.39 0.803 2.4 PRS_PLINK_0.0199526231496888 FALSE 586.11 Small kidney Both 61 566 11 genitourinary black 566, 61 142, 14 141, 12 141, 14 142, 21 0.192 0.136 0.157 0.8033 1.21 0.929 1.58 -0.18 0.394 0.647 0.189 0.835 0.386 1.81 0.0238 0.38 0.95 0.02228 1.02 0.486 2.16 0.444 0.358 0.216 0.6657 1.56 0.772 3.15 PRS_PLINK_0.0199526231496888 FALSE 586.12 Vesicoureteral reflux Both 54 465 11 genitourinary black 465, 54 117, 18 116, 18 116, 9 116, 9 -0.244 0.152 0.108 0.9661 0.784 0.582 1.06 -0.046 0.352 0.896 0.04769 0.955 0.479 1.9 -0.626 0.439 0.154 0.8123 0.535 0.226 1.26 -0.493 0.44 0.263 0.5805 0.611 0.258 1.45 PRS_PLINK_0.0199526231496888 FALSE 586.2 Cyst of kidney, acquired Both 262 2600 11 genitourinary black 2600, 262 650, 56 650, 65 650, 58 650, 83 0.159 0.0665 0.0167 1.776 1.17 1.03 1.34 0.147 0.189 0.434 0.3625 1.16 0.801 1.68 0.00387 0.197 0.984 0.006865 1 0.683 1.48 0.442 0.188 0.0189 1.723 1.56 1.08 2.25 PRS_PLINK_0.0199526231496888 FALSE 586.3 Vascular disorders of kidney/hypertrophy Both 26 381 11 genitourinary black 381, 26 96, 10 95, 8 95, 3 95, 5 -0.315 0.202 0.118 0.9265 0.73 0.491 1.08 -0.19 0.464 0.683 0.1658 0.827 0.333 2.05 -1.55 0.667 0.0197 1.706 0.211 0.0572 0.78 -0.6 0.539 0.266 0.5755 0.549 0.191 1.58 PRS_PLINK_0.0199526231496888 TRUE 586.4 Stricture/obstruction of ureter Both 438 4112 11 genitourinary black 4112, 438 1028, 106 1028, 114 1028, 103 1028, 115 0.0448 0.0518 0.387 0.412 1.05 0.945 1.16 0.0791 0.141 0.576 0.2397 1.08 0.82 1.43 -0.0406 0.147 0.782 0.1066 0.96 0.72 1.28 0.127 0.147 0.387 0.4122 1.14 0.851 1.51 PRS_PLINK_0.0199526231496888 FALSE 587 Kidney replaced by transpant Both 140 1929 11 genitourinary black 1929, 140 483, 39 482, 33 482, 30 482, 38 0.033 0.089 0.711 0.1482 1.03 0.868 1.23 -0.181 0.242 0.455 0.3424 0.834 0.519 1.34 -0.155 0.251 0.537 0.2702 0.856 0.523 1.4 0.0619 0.244 0.799 0.09721 1.06 0.66 1.72 PRS_PLINK_0.0199526231496888 FALSE 588 Disorders resulting from impaired renal function Both 165 2102 11 genitourinary black 2102, 165 526, 39 525, 44 525, 33 526, 49 0.15 0.0846 0.0754 1.123 1.16 0.985 1.37 0.156 0.229 0.495 0.3053 1.17 0.747 1.83 -0.171 0.245 0.485 0.3139 0.843 0.521 1.36 0.326 0.233 0.162 0.7911 1.39 0.877 2.19 PRS_PLINK_0.0199526231496888 FALSE 588.1 Renal osteodystrophy Both 31 702 11 genitourinary black 702, 31 176, 11 175, 5 175, 6 176, 9 0.0938 0.179 0.6 0.2219 1.1 0.774 1.56 -0.837 0.522 0.109 0.9626 0.433 0.156 1.21 -0.435 0.485 0.37 0.4317 0.647 0.25 1.68 -0.123 0.464 0.791 0.1016 0.885 0.357 2.19 PRS_PLINK_0.0199526231496888 TRUE 588.2 Secondary hyperparathyroidism (of renal origin) Both 114 1610 11 genitourinary black 1610, 114 403, 26 402, 31 402, 22 403, 35 0.2 0.102 0.049 1.31 1.22 1 1.49 0.237 0.273 0.386 0.4139 1.27 0.742 2.17 -0.143 0.294 0.626 0.2034 0.866 0.487 1.54 0.508 0.278 0.0681 1.167 1.66 0.963 2.87 PRS_PLINK_0.0199526231496888 FALSE 589 Abnormal results of function study of kidney Both 243 2247 11 genitourinary black 2247, 243 562, 58 562, 60 561, 47 562, 78 0.145 0.0704 0.0392 1.407 1.16 1.01 1.33 0.0483 0.192 0.802 0.09599 1.05 0.72 1.53 -0.189 0.205 0.357 0.4469 0.828 0.554 1.24 0.368 0.193 0.0564 1.249 1.44 0.99 2.11 PRS_PLINK_0.0199526231496888 FALSE 590 Pyelonephritis Both 481 4350 11 genitourinary black 4350, 481 1088, 120 1087, 102 1087, 113 1088, 146 0.0889 0.0499 0.0746 1.127 1.09 0.991 1.21 -0.164 0.141 0.245 0.6103 0.849 0.644 1.12 -0.095 0.139 0.495 0.3054 0.909 0.692 1.19 0.228 0.136 0.0924 1.034 1.26 0.963 1.64 PRS_PLINK_0.0199526231496888 FALSE 591 Urinary tract infection Both 2952 8796 11 genitourinary black 8796, 2952 2199, 736 2199, 763 2199, 700 2199, 752 0.023 0.0224 0.305 0.516 1.02 0.979 1.07 0.0618 0.0616 0.316 0.5006 1.06 0.943 1.2 -0.0587 0.0634 0.355 0.4501 0.943 0.833 1.07 0.0794 0.0643 0.217 0.6629 1.08 0.954 1.23 PRS_PLINK_0.0199526231496888 FALSE 592 Cystitis and urethritis Both 853 7004 11 genitourinary black 7004, 853 1751, 223 1751, 214 1751, 198 1751, 218 0.00687 0.0374 0.854 0.0684 1.01 0.936 1.08 -0.0391 0.102 0.701 0.154 0.962 0.788 1.17 -0.149 0.105 0.156 0.8078 0.861 0.701 1.06 -0.0157 0.106 0.882 0.05462 0.984 0.8 1.21 PRS_PLINK_0.0199526231496888 FALSE 592.1 Cystitis Both 812 6781 11 genitourinary black 6781, 812 1696, 210 1695, 201 1695, 190 1695, 211 0.0171 0.0382 0.654 0.1843 1.02 0.944 1.1 -0.0423 0.105 0.687 0.1631 0.959 0.78 1.18 -0.134 0.108 0.215 0.6685 0.875 0.709 1.08 0.00551 0.108 0.959 0.01799 1.01 0.813 1.24 PRS_PLINK_0.0199526231496888 FALSE 592.11 Acute cystitis Both 491 4469 11 genitourinary black 4469, 491 1118, 124 1117, 124 1117, 102 1117, 141 0.0702 0.0491 0.153 0.8151 1.07 0.974 1.18 0.0106 0.134 0.937 0.02829 1.01 0.778 1.31 -0.231 0.141 0.103 0.9886 0.794 0.602 1.05 0.107 0.135 0.429 0.3675 1.11 0.854 1.45 PRS_PLINK_0.0199526231496888 FALSE 592.12 Chronic cystitis Both 67 634 11 genitourinary black 634, 67 159, 16 158, 19 158, 18 159, 14 -0.0681 0.134 0.611 0.2141 0.934 0.719 1.21 0.153 0.347 0.66 0.1804 1.16 0.59 2.3 0.052 0.357 0.884 0.0534 1.05 0.523 2.12 -0.191 0.371 0.606 0.2173 0.826 0.399 1.71 PRS_PLINK_0.0199526231496888 FALSE 592.13 Chronic interstitial cystitis Both 164 1534 11 genitourinary black 1534, 164 384, 42 383, 46 383, 39 384, 37 -0.08 0.0854 0.349 0.4576 0.923 0.781 1.09 0.128 0.225 0.569 0.2445 1.14 0.732 1.77 -0.108 0.237 0.647 0.1894 0.897 0.564 1.43 -0.153 0.244 0.532 0.2738 0.858 0.532 1.39 PRS_PLINK_0.0199526231496888 FALSE 592.2 Urethritis and urethral syndrome Both 58 590 11 genitourinary black 590, 58 148, 15 147, 16 147, 11 148, 16 -0.0442 0.146 0.762 0.1182 0.957 0.719 1.27 0.101 0.367 0.784 0.1058 1.11 0.539 2.27 -0.32 0.399 0.422 0.375 0.726 0.332 1.59 0.202 0.376 0.592 0.2275 1.22 0.585 2.56 PRS_PLINK_0.0199526231496888 FALSE 593 Hematuria Both 1167 8606 11 genitourinary black 8606, 1167 2152, 291 2151, 284 2151, 321 2152, 270 0.0155 0.0322 0.629 0.2012 1.02 0.954 1.08 -0.011 0.0896 0.903 0.04448 0.989 0.83 1.18 0.0954 0.0883 0.28 0.5527 1.1 0.925 1.31 -0.0457 0.0945 0.629 0.2013 0.955 0.794 1.15 PRS_PLINK_0.0199526231496888 FALSE 593.1 Gross hematuria Both 327 3154 11 genitourinary black 3154, 327 789, 90 788, 72 788, 88 789, 77 -0.0283 0.0598 0.636 0.1965 0.972 0.865 1.09 -0.222 0.166 0.182 0.7404 0.801 0.579 1.11 -0.0443 0.16 0.781 0.1073 0.957 0.7 1.31 -0.14 0.17 0.409 0.388 0.869 0.623 1.21 PRS_PLINK_0.0199526231496888 FALSE 593.2 Microscopic hematuria Both 259 2530 11 genitourinary black 2530, 259 633, 70 632, 69 632, 66 633, 53 -0.021 0.0685 0.759 0.1197 0.979 0.856 1.12 -0.0154 0.178 0.931 0.03107 0.985 0.694 1.4 -0.0972 0.184 0.597 0.2237 0.907 0.633 1.3 -0.337 0.198 0.088 1.055 0.714 0.485 1.05 PRS_PLINK_0.0199526231496888 FALSE 594 Urinary calculus Both 1620 10668 11 genitourinary black 10668, 1620 2667, 372 2667, 409 2667, 403 2667, 435 0.0811 0.0274 0.00313 2.505 1.08 1.03 1.14 0.104 0.0772 0.176 0.7545 1.11 0.954 1.29 0.0945 0.0783 0.227 0.6431 1.1 0.943 1.28 0.16 0.0794 0.0435 1.361 1.17 1 1.37 PRS_PLINK_0.0199526231496888 FALSE 594.1 Calculus of kidney Both 1517 10628 11 genitourinary black 10628, 1517 2657, 350 2657, 383 2657, 378 2657, 405 0.0763 0.0282 0.00687 2.163 1.08 1.02 1.14 0.0965 0.0794 0.224 0.6498 1.1 0.943 1.29 0.0966 0.0804 0.23 0.6389 1.1 0.941 1.29 0.142 0.0817 0.0826 1.083 1.15 0.982 1.35 PRS_PLINK_0.0199526231496888 FALSE 594.2 Calculus of lower urinary tract Both 85 763 11 genitourinary black 763, 85 191, 21 191, 22 190, 21 191, 21 -0.106 0.115 0.354 0.451 0.899 0.718 1.13 0.0318 0.315 0.92 0.03644 1.03 0.557 1.91 -0.113 0.324 0.727 0.1386 0.893 0.473 1.69 -0.0969 0.332 0.771 0.1132 0.908 0.473 1.74 PRS_PLINK_0.0199526231496888 FALSE 594.3 Calculus of ureter Both 333 3587 11 genitourinary black 3587, 333 897, 71 897, 88 896, 83 897, 91 0.078 0.0586 0.183 0.7374 1.08 0.964 1.21 0.245 0.166 0.141 0.8509 1.28 0.922 1.77 0.18 0.17 0.289 0.5396 1.2 0.858 1.67 0.24 0.173 0.165 0.7819 1.27 0.906 1.79 PRS_PLINK_0.0199526231496888 FALSE 594.8 Renal colic Both 102 1106 11 genitourinary black 1106, 102 277, 22 276, 30 276, 28 277, 22 -0.00869 0.106 0.935 0.02928 0.991 0.805 1.22 0.323 0.287 0.261 0.5837 1.38 0.787 2.42 0.273 0.301 0.365 0.4371 1.31 0.728 2.37 -0.00881 0.319 0.978 0.00968 0.991 0.53 1.85 PRS_PLINK_0.0199526231496888 FALSE 595 Hydronephrosis Both 441 4355 11 genitourinary black 4355, 441 1089, 103 1089, 106 1088, 113 1089, 119 0.079 0.0509 0.12 0.9202 1.08 0.98 1.2 0.0206 0.144 0.887 0.05225 1.02 0.769 1.35 0.0512 0.145 0.723 0.1408 1.05 0.793 1.4 0.146 0.146 0.319 0.4968 1.16 0.869 1.54 PRS_PLINK_0.0199526231496888 FALSE 596 Other disorders of bladder Both 760 6786 11 genitourinary black 6786, 760 1696, 190 1696, 189 1696, 199 1697, 182 -0.025 0.039 0.522 0.2824 0.975 0.904 1.05 -0.0108 0.108 0.92 0.0361 0.989 0.8 1.22 0.0257 0.108 0.813 0.0901 1.03 0.83 1.27 -0.0838 0.114 0.462 0.3356 0.92 0.736 1.15 PRS_PLINK_0.0199526231496888 FALSE 596.1 Bladder neck obstruction Both 67 739 11 genitourinary black 739, 67 185, 19 185, 17 184, 20 185, 11 -0.159 0.132 0.227 0.6433 0.853 0.658 1.1 -0.114 0.344 0.741 0.1301 0.893 0.455 1.75 -0.0188 0.332 0.955 0.02009 0.981 0.512 1.88 -0.595 0.386 0.124 0.9073 0.552 0.259 1.18 PRS_PLINK_0.0199526231496888 FALSE 596.5 Functional disorders of bladder Both 452 4179 11 genitourinary black 4179, 452 1044, 110 1045, 101 1044, 125 1045, 116 0.0178 0.0508 0.726 0.1392 1.02 0.922 1.12 -0.0928 0.144 0.52 0.2836 0.911 0.687 1.21 0.0865 0.14 0.536 0.2711 1.09 0.829 1.43 -0.0422 0.146 0.773 0.1121 0.959 0.72 1.28 PRS_PLINK_0.0199526231496888 FALSE 597 Other disorders of urethra and urinary tract Both 299 2694 11 genitourinary black 2694, 299 674, 68 673, 79 673, 70 674, 82 0.0609 0.0629 0.333 0.4778 1.06 0.94 1.2 0.151 0.173 0.384 0.4151 1.16 0.828 1.63 -0.0151 0.181 0.934 0.02988 0.985 0.691 1.4 0.166 0.179 0.356 0.4482 1.18 0.83 1.68 PRS_PLINK_0.0199526231496888 FALSE 597.1 Urethral stricture (not specified as infectious) Both 132 1249 11 genitourinary black 1249, 132 313, 27 312, 35 312, 25 312, 45 0.132 0.0928 0.155 0.8092 1.14 0.951 1.37 0.277 0.264 0.294 0.5319 1.32 0.787 2.21 -0.0712 0.287 0.804 0.09455 0.931 0.53 1.64 0.605 0.27 0.0252 1.599 1.83 1.08 3.11 PRS_PLINK_0.0199526231496888 FALSE 597.2 Urinary complications NEC Both 268 2385 11 genitourinary black 2385, 268 597, 67 596, 72 596, 52 596, 77 0.0315 0.0655 0.63 0.2006 1.03 0.908 1.17 0.0509 0.179 0.776 0.1103 1.05 0.741 1.49 -0.25 0.194 0.197 0.7051 0.779 0.533 1.14 0.158 0.183 0.388 0.4112 1.17 0.819 1.67 PRS_PLINK_0.0199526231496888 FALSE 597.8 Urethral hypermobility/ISD Both 53 500 11 genitourinary black 500, 53 125, 13 125, 18 125, 12 125, 10 -0.0296 0.149 0.842 0.07462 0.971 0.725 1.3 0.376 0.382 0.326 0.4872 1.46 0.688 3.08 -0.125 0.411 0.761 0.1188 0.882 0.394 1.97 -0.499 0.432 0.248 0.605 0.607 0.26 1.42 PRS_PLINK_0.0199526231496888 FALSE 598 Abnormal findings on examination of urine Both 29 317 11 genitourinary black 317, 29 80, 9 79, 8 79, 6 79, 6 -0.346 0.202 0.0865 1.063 0.707 0.476 1.05 -0.24 0.504 0.634 0.198 0.786 0.293 2.11 -0.407 0.523 0.436 0.3605 0.665 0.239 1.85 -0.386 0.532 0.468 0.3295 0.68 0.239 1.93 PRS_PLINK_0.0199526231496888 TRUE 598.4 Other cells and casts in urine Both 24 281 11 genitourinary black 281, 24 71, 6 70, 8 70, 5 70, 5 -0.253 0.223 0.257 0.5893 0.777 0.502 1.2 0.198 0.553 0.72 0.1425 1.22 0.412 3.61 -0.422 0.613 0.492 0.3084 0.656 0.197 2.18 -0.0348 0.615 0.955 0.02006 0.966 0.29 3.22 PRS_PLINK_0.0199526231496888 TRUE 599 Other symptoms/disorders or the urinary system Both 3751 8550 11 genitourinary black 8550, 3751 2138, 976 2137, 936 2137, 930 2138, 909 0.00732 0.0205 0.72 0.1424 1.01 0.968 1.05 -0.031 0.0563 0.582 0.2352 0.969 0.868 1.08 -0.0455 0.057 0.425 0.3719 0.956 0.855 1.07 -0.022 0.0589 0.708 0.1497 0.978 0.872 1.1 PRS_PLINK_0.0199526231496888 FALSE 599.1 Urinary obstruction Both 154 1356 11 genitourinary black 1356, 154 339, 45 339, 40 339, 31 339, 38 -0.0335 0.0876 0.702 0.1535 0.967 0.814 1.15 -0.104 0.228 0.648 0.1885 0.901 0.577 1.41 -0.363 0.246 0.141 0.8512 0.696 0.429 1.13 -0.0411 0.246 0.867 0.06188 0.96 0.593 1.55 PRS_PLINK_0.0199526231496888 FALSE 599.2 Retention of urine Both 1316 7592 11 genitourinary black 7592, 1316 1898, 348 1898, 337 1898, 325 1898, 305 -0.0224 0.0309 0.469 0.329 0.978 0.92 1.04 -0.00879 0.0846 0.917 0.0375 0.991 0.84 1.17 -0.0771 0.0865 0.373 0.4284 0.926 0.781 1.1 -0.108 0.0899 0.231 0.6366 0.898 0.753 1.07 PRS_PLINK_0.0199526231496888 FALSE 599.3 Dysuria Both 1335 7875 11 genitourinary black 7875, 1335 1969, 333 1969, 321 1968, 347 1969, 334 0.0136 0.0308 0.658 0.1819 1.01 0.954 1.08 -0.0384 0.0854 0.653 0.1851 0.962 0.814 1.14 0.0273 0.0851 0.748 0.126 1.03 0.87 1.21 0.0155 0.0886 0.861 0.06483 1.02 0.854 1.21 PRS_PLINK_0.0199526231496888 FALSE 599.4 Urinary incontinence Both 1375 7498 11 genitourinary black 7498, 1375 1875, 345 1874, 360 1874, 335 1875, 335 0.000524 0.0305 0.986 0.005988 1 0.942 1.06 0.0586 0.0834 0.482 0.3171 1.06 0.901 1.25 -0.0382 0.0859 0.657 0.1826 0.963 0.813 1.14 0.00482 0.0887 0.957 0.01923 1 0.845 1.2 PRS_PLINK_0.0199526231496888 FALSE 599.5 Frequency of urination and polyuria Both 1366 8078 11 genitourinary black 8078, 1366 2020, 360 2019, 360 2019, 325 2020, 321 -0.00934 0.0303 0.758 0.1204 0.991 0.934 1.05 0.0111 0.0818 0.892 0.04969 1.01 0.861 1.19 -0.107 0.0848 0.208 0.6824 0.899 0.761 1.06 -0.0465 0.0875 0.595 0.2253 0.955 0.804 1.13 PRS_PLINK_0.0199526231496888 FALSE 599.6 Oliguria and anuria Both 191 1278 11 genitourinary black 1278, 191 320, 44 319, 53 319, 48 320, 46 0.0129 0.0791 0.87 0.0605 1.01 0.868 1.18 0.165 0.218 0.45 0.3471 1.18 0.769 1.81 0.112 0.224 0.618 0.2092 1.12 0.721 1.73 0.0232 0.234 0.921 0.03571 1.02 0.647 1.62 PRS_PLINK_0.0199526231496888 FALSE 599.7 Urethral discharge Both 14 224 11 genitourinary black 224, 14 56, 3 56, 3 56, 5 56, 3 0.155 0.254 0.541 0.2664 1.17 0.71 1.92 -0.342 0.72 0.635 0.1975 0.71 0.173 2.91 0.189 0.653 0.772 0.1125 1.21 0.336 4.34 0.115 0.738 0.877 0.05714 1.12 0.264 4.77 PRS_PLINK_0.0199526231496888 TRUE 599.8 Other symptoms involving urinary system Both 1317 7774 11 genitourinary black 7774, 1317 1944, 366 1943, 320 1943, 331 1944, 300 -0.0346 0.0309 0.263 0.5803 0.966 0.909 1.03 -0.124 0.0843 0.141 0.8516 0.883 0.749 1.04 -0.0992 0.0847 0.241 0.6174 0.906 0.767 1.07 -0.145 0.0894 0.105 0.9789 0.865 0.726 1.03 PRS_PLINK_0.0199526231496888 FALSE 599.9 Other abnormality of urination Both 741 6682 11 genitourinary black 6682, 741 1671, 190 1670, 195 1670, 182 1671, 174 -0.0115 0.0398 0.773 0.1121 0.989 0.914 1.07 0.024 0.108 0.824 0.08404 1.02 0.829 1.27 -0.0898 0.111 0.419 0.3774 0.914 0.735 1.14 -0.0807 0.116 0.485 0.314 0.922 0.735 1.16 PRS_PLINK_0.0199526231496888 FALSE 600 Hyperplasia of prostate Male 699 2150 11 genitourinary black 2150, 699 538, 186 537, 180 537, 180 538, 153 -0.0154 0.0465 0.741 0.1303 0.985 0.899 1.08 0.0177 0.13 0.891 0.05006 1.02 0.79 1.31 -0.019 0.132 0.885 0.05305 0.981 0.758 1.27 -0.0934 0.139 0.501 0.3001 0.911 0.694 1.2 PRS_PLINK_0.0199526231496888 FALSE 601 Inflammatory diseases of prostate Male 168 1853 11 genitourinary black 1853, 168 464, 34 463, 50 463, 49 463, 35 -0.00679 0.0817 0.934 0.02978 0.993 0.846 1.17 0.407 0.229 0.0758 1.121 1.5 0.959 2.35 0.453 0.239 0.0577 1.239 1.57 0.985 2.51 0.356 0.269 0.185 0.7322 1.43 0.843 2.42 PRS_PLINK_0.0199526231496888 FALSE 601.1 Prostatitis Male 76 832 11 genitourinary black 832, 76 208, 15 208, 22 208, 24 208, 15 -0.0866 0.122 0.478 0.3208 0.917 0.722 1.16 0.424 0.341 0.214 0.6701 1.53 0.783 2.98 0.541 0.342 0.113 0.9452 1.72 0.879 3.36 0.39 0.402 0.332 0.4792 1.48 0.672 3.25 PRS_PLINK_0.0199526231496888 FALSE 601.11 Acute prostatitis Male 26 211 11 genitourinary black 211, 26 53, 8 53, 2 52, 9 53, 7 -0.133 0.218 0.541 0.2666 0.875 0.57 1.34 -1.42 0.735 0.0528 1.277 0.241 0.057 1.02 -0.139 0.598 0.816 0.08839 0.87 0.27 2.81 0.273 0.624 0.662 0.1792 1.31 0.387 4.46 PRS_PLINK_0.0199526231496888 TRUE 601.12 Chronic prostatitis Male 15 182 11 genitourinary black 182, 15 46, 2 45, 7 45, 4 46, 2 -0.12 0.276 0.663 0.1787 0.887 0.516 1.52 0.813 0.765 0.288 0.5407 2.26 0.503 10.1 1.34 0.874 0.124 0.9064 3.83 0.692 21.2 -0.207 0.79 0.794 0.1004 0.813 0.173 3.83 PRS_PLINK_0.0199526231496888 TRUE 601.3 Orchitis and epididymitis Male 64 754 11 genitourinary black 754, 64 189, 12 188, 17 188, 19 189, 16 0.149 0.129 0.247 0.6077 1.16 0.902 1.49 0.334 0.372 0.369 0.4329 1.4 0.674 2.9 0.551 0.393 0.161 0.7938 1.73 0.803 3.75 0.618 0.413 0.135 0.8705 1.86 0.825 4.17 PRS_PLINK_0.0199526231496888 FALSE 601.4 Balanoposthitis Male 19 224 11 genitourinary black 224, 19 56, 2 56, 11 56, 2 56, 4 -0.138 0.224 0.538 0.2694 0.871 0.561 1.35 1.83 0.721 0.0111 1.956 6.24 1.52 25.7 -0.0863 0.816 0.916 0.03821 0.917 0.185 4.54 0.697 0.889 0.433 0.3636 2.01 0.352 11.5 PRS_PLINK_0.0199526231496888 TRUE 601.8 Other inflammatory disorders of male genital organs Male 25 298 11 genitourinary black 298, 25 75, 6 74, 5 74, 8 75, 6 0.0378 0.195 0.846 0.07247 1.04 0.709 1.52 -0.136 0.578 0.814 0.08914 0.873 0.281 2.71 0.241 0.554 0.663 0.1782 1.27 0.43 3.77 0.0303 0.617 0.961 0.01733 1.03 0.307 3.46 PRS_PLINK_0.0199526231496888 TRUE 602 Other disorders of prostate Male 49 567 11 genitourinary black 567, 49 142, 17 142, 13 141, 8 142, 11 -0.0656 0.145 0.651 0.1865 0.937 0.705 1.24 -0.314 0.38 0.408 0.3889 0.73 0.346 1.54 -0.574 0.431 0.182 0.7396 0.563 0.242 1.31 -0.366 0.423 0.388 0.4117 0.694 0.303 1.59 PRS_PLINK_0.0199526231496888 TRUE 602.3 Dysplasia of prostate Male 8 117 11 genitourinary black 117, 8 30, 3 29, 2 29, 2 29, 1 0.039 0.324 0.904 0.04375 1.04 0.551 1.96 -0.266 0.846 0.753 0.1233 0.766 0.146 4.02 0.291 1.1 0.792 0.1013 1.34 0.154 11.6 -0.439 1.13 0.699 0.1555 0.645 0.0698 5.96 PRS_PLINK_0.0199526231496888 TRUE 603 Other disorders of testis Male 72 867 11 genitourinary black 867, 72 217, 18 217, 15 216, 23 217, 16 0.0398 0.121 0.743 0.1292 1.04 0.821 1.32 -0.191 0.349 0.585 0.233 0.826 0.417 1.64 0.23 0.322 0.475 0.3229 1.26 0.669 2.37 -0.0725 0.352 0.837 0.07746 0.93 0.467 1.85 PRS_PLINK_0.0199526231496888 FALSE 603.1 Hydrocele Male 40 559 11 genitourinary black 559, 40 140, 10 140, 8 139, 13 140, 9 0.0154 0.16 0.923 0.03464 1.02 0.742 1.39 -0.266 0.459 0.563 0.2498 0.767 0.312 1.88 0.185 0.428 0.666 0.1766 1.2 0.52 2.78 0.0592 0.469 0.9 0.04598 1.06 0.423 2.66 PRS_PLINK_0.0199526231496888 TRUE 603.2 Spermatocele Male 29 325 11 genitourinary black 325, 29 82, 7 81, 7 81, 11 81, 4 -0.129 0.189 0.493 0.3069 0.879 0.607 1.27 0.0852 0.524 0.871 0.0601 1.09 0.39 3.04 0.377 0.483 0.435 0.3618 1.46 0.566 3.76 -0.359 0.588 0.541 0.2665 0.698 0.22 2.21 PRS_PLINK_0.0199526231496888 TRUE 604 Disorders of penis Male 117 1264 11 genitourinary black 1264, 117 316, 36 316, 33 316, 23 316, 25 -0.189 0.0966 0.0499 1.302 0.827 0.685 1 -0.0972 0.25 0.698 0.1563 0.907 0.555 1.48 -0.367 0.277 0.186 0.7308 0.693 0.403 1.19 -0.492 0.284 0.0832 1.08 0.611 0.35 1.07 PRS_PLINK_0.0199526231496888 FALSE 604.1 Redundant prepuce and phimosis/BXO Male 21 263 11 genitourinary black 263, 21 66, 6 66, 6 65, 1 66, 8 -0.0224 0.23 0.922 0.03504 0.978 0.622 1.54 -0.0316 0.564 0.955 0.01986 0.969 0.321 2.92 -1.93 0.987 0.0506 1.296 0.145 0.021 1 0.131 0.556 0.813 0.08983 1.14 0.384 3.39 PRS_PLINK_0.0199526231496888 TRUE 604.3 Peyronie's disease Male 43 386 11 genitourinary black 386, 43 97, 11 96, 10 96, 14 97, 8 -0.0665 0.165 0.688 0.1625 0.936 0.677 1.29 -0.141 0.437 0.747 0.1268 0.868 0.369 2.05 0.262 0.414 0.527 0.2779 1.3 0.577 2.92 -0.487 0.49 0.32 0.495 0.614 0.235 1.6 PRS_PLINK_0.0199526231496888 TRUE 605 Erectile dysfunction [ED] Male 607 2448 11 genitourinary black 2448, 607 612, 161 612, 167 612, 151 612, 128 -0.066 0.0471 0.16 0.7946 0.936 0.854 1.03 0.064 0.127 0.613 0.2125 1.07 0.832 1.37 -0.0445 0.132 0.736 0.1332 0.956 0.739 1.24 -0.187 0.141 0.184 0.736 0.829 0.629 1.09 PRS_PLINK_0.0199526231496888 FALSE 608 Other disorders of male genital organs Male 315 2734 11 genitourinary black 2734, 315 684, 79 683, 68 683, 94 684, 74 0.0602 0.0606 0.32 0.4942 1.06 0.943 1.2 -0.123 0.174 0.479 0.3195 0.884 0.628 1.24 0.198 0.166 0.233 0.6326 1.22 0.88 1.69 0.064 0.181 0.723 0.1408 1.07 0.748 1.52 PRS_PLINK_0.0199526231496888 FALSE 609 Male infertility and abnormal spermatozoa Male 109 923 11 genitourinary black 923, 109 231, 29 231, 29 230, 25 231, 26 -0.0552 0.102 0.588 0.2305 0.946 0.775 1.16 -0.0431 0.275 0.875 0.05788 0.958 0.559 1.64 -0.196 0.29 0.499 0.3022 0.822 0.465 1.45 -0.102 0.295 0.73 0.1366 0.903 0.506 1.61 PRS_PLINK_0.0199526231496888 FALSE 609.1 Infertility, male Male 91 688 11 genitourinary black 688, 91 172, 23 172, 27 172, 20 172, 21 -0.105 0.112 0.351 0.4551 0.9 0.722 1.12 0.0943 0.3 0.753 0.1232 1.1 0.611 1.98 -0.266 0.325 0.414 0.3829 0.767 0.405 1.45 -0.209 0.331 0.527 0.278 0.811 0.424 1.55 PRS_PLINK_0.0199526231496888 FALSE 609.11 Azoospermia and oligospermia Male 32 229 11 genitourinary black 229, 32 58, 7 57, 14 57, 4 57, 7 -0.136 0.202 0.501 0.2999 0.873 0.588 1.3 0.555 0.483 0.251 0.6009 1.74 0.676 4.49 -0.546 0.615 0.375 0.4265 0.579 0.174 1.93 -0.0919 0.564 0.87 0.06026 0.912 0.302 2.75 PRS_PLINK_0.0199526231496888 TRUE 609.2 Abnormal spermatozoa Male 33 331 11 genitourinary black 331, 33 83, 11 83, 7 82, 7 83, 8 0.0566 0.182 0.756 0.1217 1.06 0.741 1.51 0.0197 0.518 0.97 0.01334 1.02 0.369 2.82 -0.449 0.522 0.389 0.4096 0.638 0.229 1.77 0.0585 0.528 0.912 0.04007 1.06 0.376 2.99 PRS_PLINK_0.0199526231496888 TRUE 610 Benign mammary dysplasias Female 1245 5773 11 genitourinary black 5773, 1245 1444, 354 1443, 322 1443, 295 1443, 274 -0.0451 0.0327 0.168 0.7751 0.956 0.897 1.02 -0.051 0.0872 0.559 0.2528 0.95 0.801 1.13 -0.127 0.0899 0.156 0.806 0.88 0.738 1.05 -0.113 0.0939 0.227 0.6432 0.893 0.743 1.07 PRS_PLINK_0.0199526231496888 FALSE 610.1 Cystic mastopathy Female 543 4445 11 genitourinary black 4445, 543 1112, 146 1111, 135 1111, 132 1111, 130 -0.0113 0.0469 0.809 0.09205 0.989 0.902 1.08 -0.0171 0.128 0.894 0.04883 0.983 0.765 1.26 -0.0518 0.129 0.688 0.1622 0.949 0.737 1.22 -0.003 0.133 0.982 0.007885 0.997 0.768 1.29 PRS_PLINK_0.0199526231496888 FALSE 610.2 Fibroadenosis of breast Female 27 205 11 genitourinary black 205, 27 52, 1 51, 7 51, 14 51, 5 0.41 0.215 0.0562 1.25 1.51 0.989 2.3 2 0.907 0.0277 1.558 7.37 1.25 43.6 2.49 0.848 0.00335 2.475 12 2.28 63.4 1.55 0.981 0.115 0.94 4.7 0.687 32.1 PRS_PLINK_0.0199526231496888 TRUE 610.4 Benign neoplasm of breast Female 974 5715 11 genitourinary black 5715, 974 1429, 275 1429, 267 1428, 225 1429, 207 -0.0665 0.0361 0.0658 1.182 0.936 0.872 1 0.0113 0.095 0.905 0.04317 1.01 0.84 1.22 -0.154 0.0998 0.123 0.9103 0.857 0.705 1.04 -0.158 0.105 0.13 0.8862 0.854 0.695 1.05 PRS_PLINK_0.0199526231496888 FALSE 610.8 Other specified benign mammary dysplasias Female 437 3766 11 genitourinary black 3766, 437 942, 116 941, 112 941, 107 942, 102 -0.0304 0.0519 0.558 0.2535 0.97 0.876 1.07 0.0206 0.141 0.884 0.05372 1.02 0.774 1.35 -0.0339 0.143 0.813 0.09006 0.967 0.73 1.28 -0.043 0.148 0.772 0.1125 0.958 0.716 1.28 PRS_PLINK_0.0199526231496888 FALSE 611 Abnormal findings on mammogram or breast exam Both 1978 6161 11 genitourinary black 6161, 1978 1541, 557 1540, 529 1540, 478 1540, 414 -0.0432 0.0275 0.116 0.9338 0.958 0.907 1.01 0.00672 0.0727 0.926 0.03321 1.01 0.873 1.16 -0.086 0.075 0.252 0.5993 0.918 0.792 1.06 -0.144 0.0796 0.0709 1.15 0.866 0.741 1.01 PRS_PLINK_0.0199526231496888 FALSE 611.1 Abnormal mammogram Both 1571 5362 11 genitourinary black 5362, 1571 1341, 447 1340, 416 1340, 374 1341, 334 -0.0436 0.0304 0.152 0.8184 0.957 0.902 1.02 -0.016 0.0805 0.843 0.07439 0.984 0.841 1.15 -0.11 0.0831 0.187 0.7291 0.896 0.761 1.05 -0.143 0.0876 0.102 0.9931 0.866 0.73 1.03 PRS_PLINK_0.0199526231496888 FALSE 611.11 Mammographic microcalcification Both 309 2737 11 genitourinary black 2737, 309 685, 93 684, 78 684, 76 684, 62 -0.129 0.0621 0.0379 1.421 0.879 0.778 0.993 -0.135 0.163 0.406 0.3915 0.873 0.635 1.2 -0.132 0.166 0.424 0.3724 0.876 0.633 1.21 -0.341 0.178 0.0551 1.259 0.711 0.502 1.01 PRS_PLINK_0.0199526231496888 FALSE 611.3 Lump or mass in breast Both 1224 6154 11 genitourinary black 6154, 1224 1539, 330 1538, 328 1538, 307 1539, 259 -0.0321 0.0328 0.328 0.4835 0.968 0.908 1.03 0.0407 0.0871 0.64 0.1937 1.04 0.878 1.24 -0.0224 0.0894 0.802 0.09572 0.978 0.821 1.17 -0.103 0.0958 0.282 0.5499 0.902 0.748 1.09 PRS_PLINK_0.0199526231496888 FALSE 612 Breast conditions, congenital or relating to hormones Both 401 3595 11 genitourinary black 3595, 401 899, 82 899, 115 898, 110 899, 94 0.0335 0.0547 0.541 0.2669 1.03 0.929 1.15 0.348 0.152 0.0216 1.665 1.42 1.05 1.91 0.327 0.155 0.0352 1.454 1.39 1.02 1.88 0.191 0.165 0.245 0.6109 1.21 0.877 1.67 PRS_PLINK_0.0199526231496888 FALSE 612.1 Galactorrhea Both 73 579 11 genitourinary black 579, 73 145, 12 145, 26 144, 23 145, 12 -0.0745 0.133 0.576 0.2399 0.928 0.715 1.2 0.734 0.365 0.044 1.357 2.08 1.02 4.26 0.578 0.367 0.116 0.9372 1.78 0.868 3.66 0.0388 0.427 0.928 0.03266 1.04 0.451 2.4 PRS_PLINK_0.0199526231496888 FALSE 612.2 Hypertrophy of breast (Gynecomastia) Both 264 2536 11 genitourinary black 2536, 264 634, 57 634, 67 634, 73 634, 67 0.0844 0.066 0.201 0.6974 1.09 0.956 1.24 0.213 0.188 0.258 0.5885 1.24 0.856 1.79 0.294 0.187 0.117 0.9331 1.34 0.929 1.94 0.184 0.196 0.348 0.4578 1.2 0.818 1.77 PRS_PLINK_0.0199526231496888 FALSE 612.3 Congenital anomalies of breast Both 44 323 11 genitourinary black 323, 44 81, 18 81, 8 80, 9 81, 9 -0.23 0.163 0.158 0.8018 0.794 0.577 1.09 -0.86 0.442 0.0517 1.287 0.423 0.178 1.01 -0.683 0.452 0.131 0.8829 0.505 0.208 1.23 PRS_PLINK_0.0199526231496888 TRUE 613 Other nonmalignant breast conditions Both 1382 7375 11 genitourinary black 7375, 1382 1844, 349 1844, 369 1843, 352 1844, 311 -0.0129 0.0306 0.673 0.1718 0.987 0.93 1.05 0.0995 0.0825 0.228 0.6426 1.1 0.94 1.3 0.0783 0.0845 0.354 0.4513 1.08 0.916 1.28 0.0147 0.0895 0.87 0.06056 1.01 0.852 1.21 PRS_PLINK_0.0199526231496888 FALSE 613.1 Inflammatory disease of breast Both 214 2002 11 genitourinary black 2002, 214 501, 48 500, 55 500, 56 501, 55 0.0731 0.0735 0.32 0.4944 1.08 0.931 1.24 0.185 0.209 0.375 0.4261 1.2 0.799 1.81 0.286 0.211 0.176 0.7545 1.33 0.88 2.01 0.191 0.218 0.382 0.4181 1.21 0.789 1.86 PRS_PLINK_0.0199526231496888 FALSE 613.5 Mastodynia Both 614 5297 11 genitourinary black 5297, 614 1325, 158 1324, 151 1324, 164 1324, 140 -0.00298 0.0447 0.947 0.02376 0.997 0.913 1.09 -0.0113 0.121 0.926 0.03353 0.989 0.781 1.25 0.0863 0.12 0.471 0.3268 1.09 0.862 1.38 -0.058 0.127 0.648 0.1883 0.944 0.736 1.21 PRS_PLINK_0.0199526231496888 FALSE 613.7 Other signs and symptoms in breast Both 323 2925 11 genitourinary black 2925, 323 732, 74 731, 85 731, 88 731, 76 -5.01e-05 0.0612 0.999 0.0002835 1 0.887 1.13 0.156 0.167 0.349 0.4566 1.17 0.843 1.62 0.261 0.169 0.122 0.9151 1.3 0.933 1.81 0.108 0.178 0.544 0.264 1.11 0.786 1.58 PRS_PLINK_0.0199526231496888 FALSE 613.8 Other specified disorders of breast Both 333 3058 11 genitourinary black 3058, 333 765, 80 764, 91 764, 88 765, 74 -0.0393 0.0603 0.514 0.2892 0.961 0.854 1.08 0.147 0.162 0.361 0.4421 1.16 0.844 1.59 0.136 0.165 0.408 0.3891 1.15 0.83 1.58 -0.0386 0.177 0.827 0.08245 0.962 0.68 1.36 PRS_PLINK_0.0199526231496888 FALSE 613.9 Breast disorder NOS Both 453 4086 11 genitourinary black 4086, 453 1022, 118 1021, 121 1021, 112 1022, 102 -0.0746 0.051 0.143 0.8441 0.928 0.84 1.03 -0.0177 0.14 0.9 0.04596 0.982 0.746 1.29 -0.105 0.147 0.476 0.3226 0.9 0.674 1.2 PRS_PLINK_0.0199526231496888 FALSE 614 Inflammatory diseases of female pelvic organs Female 1576 6583 11 genitourinary black 6583, 1576 1645, 409 1646, 400 1645, 381 1646, 386 -0.0115 0.0293 0.695 0.1578 0.989 0.933 1.05 -0.0263 0.0793 0.74 0.1306 0.974 0.834 1.14 -0.0822 0.0813 0.312 0.5064 0.921 0.785 1.08 -0.0792 0.0835 0.343 0.4649 0.924 0.784 1.09 PRS_PLINK_0.0199526231496888 FALSE 614.1 Pelvic peritoneal adhesions, female (postoperative) (postinfection) Female 137 1248 11 genitourinary black 1248, 137 311, 33 312, 28 312, 33 312, 43 0.039 0.0922 0.673 0.1723 1.04 0.868 1.25 -0.196 0.266 0.463 0.3347 0.822 0.488 1.39 0.017 0.257 0.947 0.02348 1.02 0.615 1.68 0.229 0.25 0.36 0.4433 1.26 0.77 2.05 PRS_PLINK_0.0199526231496888 FALSE 614.3 Pelvic inflammatory disease (PID) Female 204 1821 11 genitourinary black 1821, 204 455, 47 455, 55 455, 51 455, 51 0.0545 0.0769 0.479 0.3196 1.06 0.908 1.23 0.15 0.208 0.47 0.3278 1.16 0.773 1.75 0.108 0.214 0.615 0.2111 1.11 0.732 1.69 0.11 0.224 0.623 0.2056 1.12 0.72 1.73 PRS_PLINK_0.0199526231496888 FALSE 614.31 Acute inflammatory pelvic disease Female 51 428 11 genitourinary black 428, 51 107, 10 107, 16 107, 13 107, 12 0.112 0.155 0.471 0.3267 1.12 0.825 1.52 0.395 0.408 0.332 0.4782 1.48 0.668 3.3 0.367 0.437 0.4 0.3974 1.44 0.613 3.4 0.158 0.45 0.725 0.1394 1.17 0.485 2.83 PRS_PLINK_0.0199526231496888 FALSE 614.32 Chronic inflammatory pelvic disease Female 83 662 11 genitourinary black 662, 83 165, 27 165, 15 165, 19 166, 22 0.0107 0.122 0.93 0.03134 1.01 0.795 1.28 -0.539 0.335 0.108 0.9676 0.584 0.303 1.12 -0.258 0.32 0.419 0.3779 0.772 0.413 1.44 -0.297 0.324 0.358 0.4456 0.743 0.394 1.4 PRS_PLINK_0.0199526231496888 FALSE 614.33 Pelvic inflammatory disease, NOS Female 104 927 11 genitourinary black 927, 104 231, 21 232, 34 231, 23 232, 26 0.00381 0.106 0.971 0.01263 1 0.815 1.24 0.438 0.288 0.128 0.8935 1.55 0.882 2.72 0.159 0.315 0.613 0.2122 1.17 0.633 2.17 0.205 0.318 0.519 0.2848 1.23 0.659 2.29 PRS_PLINK_0.0199526231496888 FALSE 614.4 Inflammatory diseases of uterus, except cervix Female 86 739 11 genitourinary black 739, 86 185, 19 185, 24 184, 18 185, 25 0.19 0.122 0.12 0.9197 1.21 0.952 1.54 0.358 0.328 0.275 0.5613 1.43 0.753 2.72 -0.0292 0.348 0.933 0.03004 0.971 0.491 1.92 0.538 0.343 0.116 0.9337 1.71 0.875 3.36 PRS_PLINK_0.0199526231496888 FALSE 614.5 Inflammatory disease of cervix, vagina, and vulva Female 1366 6572 11 genitourinary black 6572, 1366 1642, 357 1643, 353 1643, 322 1643, 334 -0.0133 0.0311 0.668 0.1754 0.987 0.928 1.05 -0.00616 0.0837 0.941 0.02628 0.994 0.844 1.17 -0.116 0.0867 0.182 0.7397 0.891 0.751 1.06 -0.0837 0.0886 0.345 0.4624 0.92 0.773 1.09 PRS_PLINK_0.0199526231496888 FALSE 614.51 Cervicitis and endocervicitis Female 109 1089 11 genitourinary black 1089, 109 273, 30 272, 22 272, 30 272, 27 0.0438 0.103 0.671 0.1732 1.04 0.854 1.28 -0.328 0.287 0.254 0.5947 0.721 0.41 1.27 0.0995 0.274 0.717 0.1447 1.1 0.646 1.89 -0.0403 0.286 0.888 0.05166 0.96 0.548 1.68 PRS_PLINK_0.0199526231496888 FALSE 614.52 Vaginitis and vulvovaginitis Female 1187 6481 11 genitourinary black 6481, 1187 1620, 309 1620, 309 1620, 280 1620, 289 -0.0118 0.033 0.721 0.1421 0.988 0.926 1.05 0.00311 0.0886 0.972 0.01235 1 0.843 1.19 -0.116 0.092 0.207 0.6842 0.89 0.743 1.07 -0.0797 0.0939 0.396 0.4018 0.923 0.768 1.11 PRS_PLINK_0.0199526231496888 FALSE 614.53 Cyst or abscess of Bartholin's gland Female 65 463 11 genitourinary black 463, 65 116, 15 116, 17 115, 20 116, 13 -0.124 0.156 0.428 0.3682 0.884 0.651 1.2 0.0419 0.369 0.91 0.04111 1.04 0.506 2.15 0.308 0.368 0.403 0.3951 1.36 0.661 2.8 -0.0331 0.422 0.937 0.02804 0.967 0.423 2.21 PRS_PLINK_0.0199526231496888 FALSE 614.54 Abscess or ulceration of vulva Female 90 814 11 genitourinary black 814, 90 204, 17 203, 37 203, 13 204, 23 -0.0184 0.116 0.874 0.05845 0.982 0.782 1.23 0.839 0.309 0.0066 2.181 2.32 1.26 4.24 -0.319 0.372 0.391 0.4074 0.727 0.35 1.51 0.125 0.343 0.715 0.1458 1.13 0.578 2.22 PRS_PLINK_0.0199526231496888 FALSE 615 Endometriosis Female 612 5308 11 genitourinary black 5308, 612 1326, 156 1327, 170 1327, 154 1327, 132 -0.0678 0.044 0.123 0.9085 0.934 0.857 1.02 0.0673 0.118 0.567 0.2465 1.07 0.849 1.35 -0.0807 0.122 0.509 0.2934 0.922 0.726 1.17 -0.153 0.129 0.237 0.6254 0.859 0.667 1.11 PRS_PLINK_0.0199526231496888 FALSE 618 Genital prolapse Female 681 5448 11 genitourinary black 5448, 681 1361, 186 1362, 168 1362, 161 1362, 166 -0.0444 0.0422 0.292 0.5344 0.957 0.881 1.04 -0.128 0.114 0.26 0.5843 0.88 0.704 1.1 -0.142 0.116 0.219 0.6588 0.867 0.691 1.09 -0.124 0.119 0.297 0.5269 0.884 0.7 1.11 PRS_PLINK_0.0199526231496888 FALSE 618.1 Prolapse of vaginal walls Female 425 3591 11 genitourinary black 3591, 425 898, 120 898, 103 897, 103 898, 99 -0.116 0.0531 0.0295 1.529 0.891 0.803 0.989 -0.18 0.143 0.208 0.683 0.835 0.631 1.11 -0.171 0.144 0.234 0.6315 0.843 0.636 1.12 -0.255 0.149 0.0867 1.062 0.775 0.578 1.04 PRS_PLINK_0.0199526231496888 FALSE 618.2 Uterine/Uterovaginal prolapse Female 160 1360 11 genitourinary black 1360, 160 339, 47 340, 42 340, 38 340, 33 -0.195 0.0861 0.0235 1.629 0.823 0.695 0.974 -0.167 0.226 0.46 0.3373 0.846 0.544 1.32 -0.279 0.232 0.227 0.6433 0.756 0.48 1.19 -0.551 0.25 0.0276 1.559 0.576 0.353 0.941 PRS_PLINK_0.0199526231496888 FALSE 618.5 Prolapse of vaginal vault after hysterectomy Female 90 720 11 genitourinary black 720, 90 180, 24 180, 13 180, 30 180, 23 0.0328 0.117 0.779 0.1083 1.03 0.822 1.3 -0.638 0.351 0.0694 1.158 0.528 0.265 1.05 0.239 0.299 0.423 0.3735 1.27 0.707 2.28 0.0942 0.32 0.768 0.1145 1.1 0.587 2.06 PRS_PLINK_0.0199526231496888 FALSE 618.6 Vaginal enterocele, congenital or acquired Female 143 1241 11 genitourinary black 1241, 143 311, 31 310, 42 310, 30 310, 40 0.0412 0.0897 0.646 0.1894 1.04 0.874 1.24 0.293 0.249 0.24 0.6202 1.34 0.822 2.19 -0.013 0.269 0.962 0.01704 0.987 0.582 1.67 0.241 0.259 0.351 0.4543 1.27 0.767 2.11 PRS_PLINK_0.0199526231496888 FALSE 619 Noninflammatory female genital disorders Female 2336 6197 11 genitourinary black 6197, 2336 1549, 596 1549, 629 1549, 528 1549, 583 -0.0023 0.0254 0.928 0.03249 0.998 0.949 1.05 0.0593 0.0683 0.386 0.4136 1.06 0.928 1.21 -0.113 0.0716 0.114 0.9417 0.893 0.776 1.03 -0.0117 0.0722 0.872 0.05962 0.988 0.858 1.14 PRS_PLINK_0.0199526231496888 FALSE 619.1 Noninflammatory disorders of ovary, fallopian tube, and broad ligament Female 546 4611 11 genitourinary black 4611, 546 1152, 144 1153, 137 1152, 107 1153, 158 0.0602 0.0465 0.195 0.7091 1.06 0.97 1.16 -0.032 0.127 0.801 0.09634 0.969 0.755 1.24 -0.229 0.137 0.0944 1.025 0.796 0.609 1.04 0.16 0.129 0.213 0.6721 1.17 0.912 1.51 PRS_PLINK_0.0199526231496888 FALSE 619.2 Disorders of uterus, NEC Female 216 2102 11 genitourinary black 2102, 216 526, 68 525, 50 525, 43 526, 55 -0.0517 0.0722 0.474 0.3246 0.95 0.824 1.09 -0.272 0.195 0.164 0.7839 0.762 0.52 1.12 -0.471 0.206 0.0221 1.655 0.624 0.417 0.935 -0.202 0.198 0.309 0.5097 0.817 0.554 1.21 PRS_PLINK_0.0199526231496888 FALSE 619.3 Noninflammatory disorders of cervix Female 193 1743 11 genitourinary black 1743, 193 435, 42 436, 40 435, 56 436, 55 0.135 0.077 0.0791 1.102 1.14 0.984 1.33 -0.0652 0.228 0.775 0.1108 0.937 0.599 1.46 0.335 0.215 0.12 0.92 1.4 0.916 2.13 0.381 0.221 0.0841 1.075 1.46 0.95 2.26 PRS_PLINK_0.0199526231496888 FALSE 619.4 Noninflammatory disorders of vagina Female 1079 6147 11 genitourinary black 6147, 1079 1536, 269 1537, 276 1536, 255 1537, 279 0.019 0.0345 0.581 0.2356 1.02 0.953 1.09 0.0299 0.0942 0.751 0.1246 1.03 0.857 1.24 -0.0307 0.0972 0.752 0.1237 0.97 0.802 1.17 0.0583 0.098 0.552 0.2584 1.06 0.875 1.28 PRS_PLINK_0.0199526231496888 FALSE 619.5 Noninflammatory disorders of vulva and perineum Female 435 3921 11 genitourinary black 3921, 435 980, 102 980, 133 980, 87 980, 113 0.0107 0.0522 0.837 0.0772 1.01 0.912 1.12 0.263 0.139 0.0596 1.225 1.3 0.989 1.71 -0.13 0.155 0.402 0.3957 0.878 0.648 1.19 0.0933 0.149 0.532 0.274 1.1 0.819 1.47 PRS_PLINK_0.0199526231496888 FALSE 620 Dysplasia of female genital organs Female 142 1444 11 genitourinary black 1444, 142 360, 31 361, 46 361, 29 361, 36 0.0601 0.0899 0.504 0.2979 1.06 0.89 1.27 0.375 0.241 0.12 0.9215 1.45 0.907 2.33 -0.0491 0.267 0.854 0.06862 0.952 0.565 1.61 0.1 0.263 0.704 0.1526 1.11 0.66 1.85 PRS_PLINK_0.0199526231496888 FALSE 620.1 Dysplasia of cervix Female 85 752 11 genitourinary black 752, 85 187, 22 188, 26 188, 21 188, 16 -0.0343 0.114 0.764 0.1171 0.966 0.773 1.21 0.173 0.305 0.57 0.244 1.19 0.654 2.16 -0.0392 0.319 0.902 0.04474 0.962 0.514 1.8 -0.292 0.355 0.411 0.3865 0.747 0.373 1.5 PRS_PLINK_0.0199526231496888 FALSE 621 Endometrial hyperplasia Female 113 1462 11 genitourinary black 1462, 113 366, 31 365, 32 365, 21 366, 29 0.027 0.105 0.797 0.09863 1.03 0.836 1.26 0.0377 0.259 0.884 0.0534 1.04 0.625 1.73 -0.482 0.292 0.0987 1.006 0.617 0.348 1.09 -0.0418 0.277 0.88 0.05553 0.959 0.557 1.65 PRS_PLINK_0.0199526231496888 FALSE 622 Polyp of female genital organs Female 446 4693 11 genitourinary black 4693, 446 1174, 116 1173, 115 1173, 97 1173, 118 0.0359 0.0512 0.483 0.3161 1.04 0.938 1.15 0.0126 0.138 0.927 0.0329 1.01 0.773 1.33 -0.164 0.146 0.262 0.5821 0.849 0.638 1.13 0.023 0.143 0.872 0.05951 1.02 0.774 1.35 PRS_PLINK_0.0199526231496888 FALSE 622.1 Polyp of corpus uteri Female 338 3731 11 genitourinary black 3731, 338 933, 86 933, 88 932, 78 933, 86 0.0152 0.0589 0.796 0.09888 1.02 0.905 1.14 0.0454 0.158 0.774 0.1112 1.05 0.768 1.43 -0.105 0.166 0.527 0.2779 0.9 0.65 1.25 -0.00571 0.165 0.972 0.01216 0.994 0.72 1.37 PRS_PLINK_0.0199526231496888 FALSE 622.2 Mucous polyp of cervix Female 137 1402 11 genitourinary black 1402, 137 351, 34 350, 30 350, 31 351, 42 0.128 0.0923 0.165 0.783 1.14 0.949 1.36 -0.109 0.259 0.674 0.1714 0.897 0.54 1.49 -0.0636 0.259 0.806 0.0939 0.938 0.565 1.56 0.228 0.252 0.365 0.4375 1.26 0.767 2.06 PRS_PLINK_0.0199526231496888 FALSE 623 Hypertrophy of female genital organs Female 302 2885 11 genitourinary black 2885, 302 722, 78 721, 77 721, 64 721, 83 0.0264 0.063 0.675 0.171 1.03 0.908 1.16 -0.0227 0.17 0.894 0.04888 0.978 0.701 1.36 -0.15 0.179 0.401 0.3966 0.86 0.606 1.22 -0.00224 0.173 0.99 0.004519 0.998 0.711 1.4 PRS_PLINK_0.0199526231496888 FALSE 624 Symptoms involving female genital tract Female 650 4636 11 genitourinary black 4636, 650 1159, 156 1159, 173 1159, 153 1159, 168 0.0213 0.0441 0.63 0.201 1.02 0.937 1.11 0.0988 0.118 0.404 0.394 1.1 0.875 1.39 -0.0231 0.124 0.852 0.06958 0.977 0.767 1.25 0.109 0.125 0.384 0.416 1.11 0.873 1.42 PRS_PLINK_0.0199526231496888 FALSE 624.1 Dystrophy of female genital tract Female 63 547 11 genitourinary black 547, 63 137, 14 137, 16 136, 14 137, 19 0.0791 0.137 0.563 0.2496 1.08 0.828 1.41 0.163 0.377 0.665 0.1774 1.18 0.563 2.46 -0.0476 0.403 0.906 0.04286 0.954 0.433 2.1 0.507 0.388 0.192 0.7177 1.66 0.776 3.55 PRS_PLINK_0.0199526231496888 FALSE 624.2 Atrophy of female genital tract Female 20 160 11 genitourinary black 160, 20 40, 6 40, 7 40, 1 40, 6 -0.215 0.257 0.402 0.3957 0.807 0.488 1.33 -0.0438 0.604 0.942 0.02588 0.957 0.293 3.13 -1.05 0.886 0.234 0.6301 0.349 0.0614 1.98 -0.325 0.68 0.633 0.1985 0.723 0.191 2.74 PRS_PLINK_0.0199526231496888 TRUE 624.9 stress incontinence, female Female 642 4629 11 genitourinary black 4629, 642 1158, 165 1157, 174 1157, 162 1157, 140 -0.0607 0.0436 0.163 0.787 0.941 0.864 1.02 0.0508 0.117 0.663 0.1782 1.05 0.837 1.32 -0.0308 0.12 0.797 0.09854 0.97 0.767 1.23 -0.206 0.128 0.106 0.9728 0.814 0.634 1.05 PRS_PLINK_0.0199526231496888 FALSE 625 Pain and other symptoms associated with female genital organs Female 2305 5715 11 genitourinary black 5715, 2305 1429, 588 1429, 583 1428, 541 1429, 593 0.0185 0.0257 0.473 0.3256 1.02 0.969 1.07 -0.00346 0.0701 0.961 0.01744 0.997 0.869 1.14 -0.0842 0.0721 0.243 0.615 0.919 0.798 1.06 0.0466 0.073 0.523 0.2814 1.05 0.908 1.21 PRS_PLINK_0.0199526231496888 FALSE 625.1 Dyspareunia Female 583 4558 11 genitourinary black 4558, 583 1140, 146 1139, 155 1139, 142 1140, 140 -0.0482 0.0458 0.293 0.5328 0.953 0.871 1.04 0.0445 0.123 0.718 0.144 1.05 0.821 1.33 -0.0421 0.128 0.741 0.1301 0.959 0.747 1.23 -0.0532 0.131 0.684 0.1649 0.948 0.734 1.23 PRS_PLINK_0.0199526231496888 FALSE 626 Disorders of menstruation and other abnormal bleeding from female genital tract Female 2536 5187 11 genitourinary black 5187, 2536 1296, 672 1297, 640 1296, 611 1297, 613 -0.0325 0.0256 0.205 0.6882 0.968 0.921 1.02 -0.0643 0.069 0.351 0.4545 0.938 0.819 1.07 -0.123 0.0711 0.0834 1.079 0.884 0.769 1.02 -0.121 0.0724 0.0957 1.019 0.886 0.769 1.02 PRS_PLINK_0.0199526231496888 FALSE 626.1 Irregular menstrual cycle/bleeding Female 1919 5064 11 genitourinary black 5064, 1919 1265, 507 1266, 474 1266, 469 1266, 469 -0.0145 0.0284 0.609 0.2155 0.986 0.932 1.04 -0.0737 0.0764 0.335 0.4755 0.929 0.8 1.08 -0.0893 0.0782 0.254 0.5952 0.915 0.785 1.07 -0.0964 0.08 0.228 0.6417 0.908 0.776 1.06 PRS_PLINK_0.0199526231496888 FALSE 626.11 Absent or infrequent menstruation Female 511 3731 11 genitourinary black 3731, 511 932, 128 933, 120 932, 146 933, 117 0.054 0.05 0.28 0.5527 1.06 0.957 1.16 -0.0333 0.136 0.807 0.09301 0.967 0.74 1.26 0.217 0.134 0.105 0.9802 1.24 0.956 1.61 0.0292 0.144 0.839 0.07605 1.03 0.776 1.37 PRS_PLINK_0.0199526231496888 FALSE 626.12 Excessive or frequent menstruation Female 914 4623 11 genitourinary black 4623, 914 1155, 233 1156, 246 1155, 227 1156, 208 -0.0295 0.0378 0.435 0.3617 0.971 0.902 1.05 0.0403 0.101 0.69 0.1613 1.04 0.854 1.27 -0.0318 0.104 0.761 0.1189 0.969 0.789 1.19 -0.13 0.109 0.231 0.6367 0.878 0.71 1.09 PRS_PLINK_0.0199526231496888 FALSE 626.13 Irregular menstrual cycle Female 873 4689 11 genitourinary black 4689, 873 1172, 240 1172, 215 1172, 210 1172, 208 -0.0288 0.0387 0.458 0.3395 0.972 0.901 1.05 -0.119 0.103 0.252 0.5993 0.888 0.725 1.09 -0.118 0.106 0.269 0.5708 0.889 0.722 1.09 -0.101 0.109 0.355 0.4502 0.904 0.73 1.12 PRS_PLINK_0.0199526231496888 FALSE 626.14 Irregular menstrual bleeding Female 430 3720 11 genitourinary black 3720, 430 929, 107 930, 121 930, 103 930, 99 -0.0194 0.0535 0.717 0.1443 0.981 0.883 1.09 0.129 0.141 0.361 0.4424 1.14 0.863 1.5 -0.0246 0.148 0.868 0.06148 0.976 0.73 1.3 -0.0386 0.152 0.799 0.09739 0.962 0.715 1.3 PRS_PLINK_0.0199526231496888 FALSE 626.15 Infertility, female, associated with anovulation Female 196 1776 11 genitourinary black 1776, 196 444, 50 444, 38 444, 63 444, 45 0.0889 0.0797 0.265 0.5769 1.09 0.935 1.28 -0.248 0.227 0.273 0.5634 0.78 0.5 1.22 0.314 0.205 0.125 0.9045 1.37 0.917 2.05 0.0901 0.225 0.689 0.162 1.09 0.704 1.7 PRS_PLINK_0.0199526231496888 FALSE 626.2 Dysmenorrhea Female 689 4162 11 genitourinary black 4162, 689 1040, 174 1040, 194 1040, 165 1041, 156 -0.0351 0.0433 0.417 0.3797 0.965 0.887 1.05 0.0916 0.114 0.422 0.375 1.1 0.876 1.37 -0.0658 0.12 0.585 0.2332 0.936 0.74 1.19 -0.11 0.124 0.374 0.4268 0.896 0.702 1.14 PRS_PLINK_0.0199526231496888 FALSE 626.4 Premenstrual tension syndromes Female 157 1389 11 genitourinary black 1389, 157 348, 45 347, 42 347, 36 347, 34 -0.112 0.0888 0.207 0.6841 0.894 0.751 1.06 -0.0433 0.225 0.847 0.07191 0.958 0.616 1.49 -0.214 0.237 0.367 0.4359 0.808 0.508 1.28 -0.26 0.242 0.282 0.5501 0.771 0.48 1.24 PRS_PLINK_0.0199526231496888 FALSE 626.8 Infertility, female Female 412 3103 11 genitourinary black 3103, 412 775, 102 776, 109 775, 104 776, 97 0.0489 0.0551 0.375 0.4264 1.05 0.943 1.17 0.0992 0.148 0.503 0.2987 1.1 0.826 1.48 0.0927 0.151 0.54 0.2673 1.1 0.815 1.48 0.116 0.158 0.462 0.3356 1.12 0.824 1.53 PRS_PLINK_0.0199526231496888 FALSE 627 Menopausal and postmenopausal disorders Female 1319 4567 11 genitourinary black 4567, 1319 1141, 378 1142, 355 1141, 304 1142, 282 -0.0683 0.0332 0.0393 1.405 0.934 0.875 0.997 -0.0309 0.0876 0.724 0.14 0.97 0.817 1.15 -0.187 0.0908 0.039 1.409 0.829 0.694 0.991 -0.185 0.0953 0.0517 1.287 0.831 0.689 1 PRS_PLINK_0.0199526231496888 FALSE 627.1 Postmenopausal bleeding Female 246 2497 11 genitourinary black 2497, 246 625, 73 624, 70 624, 39 624, 64 -0.0631 0.0693 0.362 0.4409 0.939 0.82 1.08 0.0077 0.178 0.966 0.01523 1.01 0.711 1.43 -0.56 0.208 0.00701 2.154 0.571 0.38 0.858 0.00772 0.189 0.967 0.01441 1.01 0.696 1.46 PRS_PLINK_0.0199526231496888 FALSE 627.2 Symptomatic menopause Female 883 4098 11 genitourinary black 4098, 883 1024, 249 1024, 221 1024, 219 1025, 194 -0.0582 0.0392 0.138 0.8604 0.943 0.874 1.02 -0.0579 0.105 0.58 0.2365 0.944 0.769 1.16 -0.11 0.106 0.301 0.5219 0.896 0.727 1.1 -0.16 0.112 0.152 0.8175 0.852 0.685 1.06 PRS_PLINK_0.0199526231496888 FALSE 627.21 Symptomatic artificial menopause Female 55 512 11 genitourinary black 512, 55 128, 14 128, 12 128, 16 128, 13 0.0755 0.144 0.601 0.2212 1.08 0.813 1.43 -0.106 0.403 0.792 0.1011 0.899 0.408 1.98 0.218 0.385 0.571 0.2437 1.24 0.585 2.65 -0.0545 0.415 0.895 0.04799 0.947 0.42 2.13 PRS_PLINK_0.0199526231496888 FALSE 627.22 Need for Hormone replacement therapy (postmenopausal) Female 88 795 11 genitourinary black 795, 88 199, 27 199, 19 198, 20 199, 22 -0.0397 0.12 0.741 0.1301 0.961 0.759 1.22 -0.355 0.312 0.254 0.5947 0.701 0.381 1.29 -0.349 0.319 0.273 0.5636 0.705 0.378 1.32 -0.146 0.312 0.64 0.1938 0.864 0.469 1.59 PRS_PLINK_0.0199526231496888 FALSE 627.3 Postmenopausal atrophic vaginitis Female 274 2251 11 genitourinary black 2251, 274 563, 81 563, 79 562, 50 563, 64 -0.0954 0.0668 0.153 0.814 0.909 0.797 1.04 -0.0241 0.171 0.888 0.05157 0.976 0.698 1.37 -0.517 0.193 0.00734 2.135 0.596 0.409 0.87 -0.269 0.185 0.147 0.8317 0.764 0.531 1.1 PRS_PLINK_0.0199526231496888 FALSE 627.4 Premenopausal menorrhagia Female 119 1308 11 genitourinary black 1308, 119 326, 29 327, 34 327, 26 327, 30 0.0432 0.0968 0.655 0.1837 1.04 0.864 1.26 0.17 0.259 0.511 0.2913 1.19 0.713 1.97 -0.0635 0.278 0.819 0.08658 0.939 0.545 1.62 0.0728 0.279 0.794 0.1 1.08 0.622 1.86 PRS_PLINK_0.0199526231496888 FALSE 627.5 Premature menopause and other ovarian failure Female 122 1235 11 genitourinary black 1235, 122 309, 39 309, 29 308, 34 309, 20 -0.0945 0.0991 0.341 0.4676 0.91 0.749 1.11 -0.307 0.256 0.231 0.6356 0.736 0.445 1.22 -0.0658 0.247 0.79 0.1022 0.936 0.577 1.52 -0.567 0.288 0.0495 1.306 0.567 0.322 0.999 PRS_PLINK_0.0199526231496888 FALSE 628 Ovarian cyst Female 852 4887 11 genitourinary black 4887, 852 1221, 231 1222, 219 1221, 197 1222, 205 -0.0142 0.0385 0.712 0.1478 0.986 0.914 1.06 -0.0476 0.104 0.647 0.1893 0.954 0.778 1.17 -0.114 0.108 0.29 0.5369 0.892 0.722 1.1 -0.0516 0.11 0.638 0.1953 0.95 0.766 1.18 PRS_PLINK_0.0199526231496888 FALSE 634 Miscarriage; stillbirth Female 423 3512 12 pregnancy complications royalblue4 3512, 423 877, 118 878, 105 878, 95 878, 105 0.0212 0.0531 0.69 0.1614 1.02 0.92 1.13 -0.114 0.142 0.422 0.375 0.892 0.675 1.18 -0.196 0.148 0.185 0.7317 0.822 0.615 1.1 0.00448 0.149 0.976 0.01053 1 0.75 1.35 PRS_PLINK_0.0199526231496888 FALSE 634.1 Missed abortion/Hydatidiform mole Female 147 1252 12 pregnancy complications royalblue4 1252, 147 313, 49 313, 38 313, 31 313, 29 -0.134 0.0924 0.147 0.8325 0.875 0.73 1.05 -0.225 0.229 0.327 0.4856 0.799 0.51 1.25 -0.416 0.245 0.089 1.051 0.66 0.408 1.07 -0.398 0.256 0.12 0.9212 0.671 0.406 1.11 PRS_PLINK_0.0199526231496888 FALSE 634.3 Ectopic pregnancy Female 56 514 12 pregnancy complications royalblue4 514, 56 129, 15 128, 14 128, 15 129, 12 -0.0357 0.147 0.809 0.09231 0.965 0.723 1.29 -0.118 0.387 0.761 0.1186 0.889 0.416 1.9 0.0233 0.387 0.952 0.02138 1.02 0.48 2.18 -0.11 0.417 0.792 0.1011 0.896 0.396 2.03 PRS_PLINK_0.0199526231496888 FALSE 635 Hemorrhage during pregnancy; childbirth and postpartum Female 345 2723 12 pregnancy complications royalblue4 2723, 345 680, 92 681, 94 680, 86 681, 73 0.00333 0.0599 0.956 0.01968 1 0.892 1.13 0.0281 0.157 0.858 0.06638 1.03 0.756 1.4 -0.0633 0.163 0.697 0.1565 0.939 0.682 1.29 -0.0932 0.175 0.594 0.2264 0.911 0.647 1.28 PRS_PLINK_0.0199526231496888 FALSE 635.2 Antepartum hemorrhage, abruptio placentae, and placenta previa Female 228 1842 12 pregnancy complications royalblue4 1842, 228 460, 53 460, 67 460, 58 461, 50 0.0436 0.0731 0.551 0.2588 1.04 0.905 1.21 0.234 0.196 0.232 0.6354 1.26 0.861 1.85 0.073 0.205 0.722 0.1413 1.08 0.719 1.61 0.0783 0.217 0.718 0.1441 1.08 0.707 1.65 PRS_PLINK_0.0199526231496888 FALSE 635.3 Placenta previa and abruptio placenta Female 181 1471 12 pregnancy complications royalblue4 1471, 181 368, 52 368, 48 367, 41 368, 40 0.0239 0.0824 0.772 0.1126 1.02 0.872 1.2 0.0074 0.215 0.973 0.01209 1.01 0.661 1.54 -0.117 0.23 0.612 0.2129 0.89 0.567 1.4 -0.108 0.24 0.652 0.1858 0.897 0.56 1.44 PRS_PLINK_0.0199526231496888 FALSE 636 Early or threatened labor; hemorrhage in early pregnancy Female 679 3785 12 pregnancy complications royalblue4 3785, 679 946, 188 946, 167 946, 170 946, 154 -0.00654 0.0436 0.881 0.05513 0.993 0.912 1.08 -0.11 0.116 0.344 0.4631 0.896 0.713 1.13 -0.101 0.118 0.393 0.4057 0.904 0.718 1.14 -0.135 0.124 0.276 0.5587 0.874 0.685 1.11 PRS_PLINK_0.0199526231496888 FALSE 636.1 Threatened premature labor Female 254 1923 12 pregnancy complications royalblue4 1923, 254 480, 71 481, 58 480, 59 481, 66 0.071 0.0689 0.303 0.5186 1.07 0.938 1.23 -0.204 0.188 0.279 0.5543 0.816 0.564 1.18 -0.17 0.19 0.37 0.4317 0.844 0.582 1.22 -0.00243 0.189 0.99 0.004463 0.998 0.688 1.45 PRS_PLINK_0.0199526231496888 FALSE 636.2 Early onset of delivery Female 166 1411 12 pregnancy complications royalblue4 1411, 166 352, 45 353, 39 352, 42 353, 40 0.00572 0.0832 0.945 0.0245 1.01 0.854 1.18 -0.103 0.227 0.65 0.1873 0.902 0.578 1.41 -0.035 0.229 0.878 0.05627 0.966 0.616 1.51 0.0264 0.239 0.912 0.03993 1.03 0.642 1.64 PRS_PLINK_0.0199526231496888 FALSE 636.3 Hemorrhage in early pregnancy Female 259 2192 12 pregnancy complications royalblue4 2192, 259 547, 70 548, 60 548, 65 548, 64 0.0581 0.0687 0.398 0.3999 1.06 0.926 1.21 -0.157 0.186 0.398 0.4001 0.855 0.594 1.23 -0.05 0.185 0.787 0.1039 0.951 0.662 1.37 -0.00458 0.192 0.981 0.008345 0.995 0.683 1.45 PRS_PLINK_0.0199526231496888 FALSE 636.8 Cervical incompetence Female 49 382 12 pregnancy complications royalblue4 382, 49 95, 13 95, 12 95, 14 96, 10 -0.052 0.152 0.732 0.1358 0.949 0.705 1.28 -0.108 0.419 0.796 0.09912 0.897 0.394 2.04 0.0789 0.401 0.844 0.07367 1.08 0.493 2.37 -0.241 0.436 0.58 0.2365 0.786 0.334 1.85 PRS_PLINK_0.0199526231496888 TRUE 637 Short gestation; low birth weight; and fetal growth retardation Both 23 282 12 pregnancy complications royalblue4 282, 23 71, 6 70, 4 70, 8 71, 5 0.00721 0.219 0.974 0.01154 1.01 0.655 1.55 0.257 0.664 0.699 0.1556 1.29 0.352 4.76 0.236 0.534 0.659 0.1809 1.27 0.444 3.61 -0.0353 0.614 0.954 0.02042 0.965 0.29 3.21 PRS_PLINK_0.0199526231496888 TRUE 642 Hypertension complicating pregnancy, childbirth, and the puerperium Female 163 3005 12 pregnancy complications royalblue4 3005, 163 751, 41 751, 32 751, 42 751, 48 0.0747 0.0832 0.369 0.4326 1.08 0.915 1.27 -0.199 0.236 0.4 0.3983 0.819 0.516 1.3 0.11 0.226 0.625 0.204 1.12 0.717 1.74 0.393 0.228 0.0845 1.073 1.48 0.948 2.31 PRS_PLINK_0.0199526231496888 FALSE 642.1 Preeclampsia and eclampsia Female 89 1563 12 pregnancy complications royalblue4 1563, 89 390, 24 391, 17 390, 25 391, 23 0.0244 0.11 0.824 0.08408 1.02 0.826 1.27 -0.298 0.311 0.338 0.4707 0.742 0.404 1.37 0.136 0.292 0.64 0.1937 1.15 0.647 2.03 0.156 0.307 0.611 0.2142 1.17 0.64 2.14 PRS_PLINK_0.0199526231496888 FALSE 643 Excessive vomiting in pregnancy Female 156 1333 12 pregnancy complications royalblue4 1333, 156 334, 42 333, 40 333, 34 333, 40 0.0125 0.0884 0.888 0.05161 1.01 0.851 1.2 -0.0425 0.232 0.854 0.06831 0.958 0.608 1.51 -0.247 0.246 0.316 0.5001 0.781 0.483 1.27 -0.0456 0.243 0.851 0.06989 0.955 0.593 1.54 PRS_PLINK_0.0199526231496888 FALSE 643.1 Hyperemesis gravidarum Female 72 586 12 pregnancy complications royalblue4 586, 72 147, 15 146, 24 146, 16 147, 17 -0.0426 0.134 0.75 0.1248 0.958 0.737 1.25 0.535 0.342 0.117 0.9303 1.71 0.874 3.34 0.0403 0.374 0.914 0.03894 1.04 0.5 2.17 -0.259 0.392 0.509 0.2933 0.772 0.358 1.66 PRS_PLINK_0.0199526231496888 FALSE 644 Anemia during pregnancy Female 133 1209 12 pregnancy complications royalblue4 1209, 133 303, 43 302, 38 302, 24 302, 28 -0.0331 0.0952 0.728 0.1378 0.967 0.803 1.17 -0.0767 0.237 0.746 0.1271 0.926 0.582 1.47 -0.476 0.27 0.0778 1.109 0.621 0.366 1.05 -0.188 0.272 0.488 0.3113 0.828 0.486 1.41 PRS_PLINK_0.0199526231496888 FALSE 646 Other complications of pregnancy NEC Female 493 3411 12 pregnancy complications royalblue4 3411, 493 852, 122 853, 127 852, 131 853, 113 0.0448 0.0504 0.375 0.4264 1.05 0.947 1.15 0.0437 0.137 0.75 0.1252 1.04 0.799 1.37 0.11 0.138 0.425 0.372 1.12 0.852 1.46 0.068 0.147 0.644 0.1912 1.07 0.802 1.43 PRS_PLINK_0.0199526231496888 FALSE 647 Infectious and parasitic complications affecting pregnancy Female 140 1072 12 pregnancy complications royalblue4 1072, 140 268, 24 268, 36 268, 40 268, 40 0.223 0.0946 0.0185 1.733 1.25 1.04 1.5 0.411 0.273 0.133 0.8777 1.51 0.883 2.58 0.561 0.273 0.0402 1.396 1.75 1.03 2.99 0.711 0.286 0.0131 1.884 2.04 1.16 3.57 PRS_PLINK_0.0199526231496888 FALSE 647.1 Infections of genitourinary tract during pregnancy Female 146 1181 12 pregnancy complications royalblue4 1181, 146 295, 33 295, 44 295, 28 295, 41 0.0827 0.0904 0.36 0.4438 1.09 0.91 1.3 0.283 0.241 0.24 0.6194 1.33 0.828 2.13 -0.215 0.273 0.431 0.3654 0.807 0.472 1.38 0.411 0.26 0.114 0.9432 1.51 0.906 2.51 PRS_PLINK_0.0199526231496888 FALSE 647.3 Major puerperal infection Female 35 342 12 pregnancy complications royalblue4 342, 35 86, 8 85, 9 85, 10 86, 8 0.202 0.18 0.262 0.5822 1.22 0.86 1.74 0.36 0.506 0.477 0.3215 1.43 0.532 3.86 0.562 0.52 0.279 0.554 1.75 0.634 4.86 0.424 0.536 0.429 0.3671 1.53 0.534 4.37 PRS_PLINK_0.0199526231496888 TRUE 649 Other conditions or status of the mother complicating pregnancy, childbirth, or the puerperium Female 737 3946 12 pregnancy complications royalblue4 3946, 737 986, 186 986, 193 986, 191 987, 167 -0.0169 0.0424 0.691 0.1607 0.983 0.905 1.07 0.0414 0.114 0.716 0.145 1.04 0.834 1.3 0.00253 0.116 0.983 0.007663 1 0.799 1.26 -0.0128 0.123 0.917 0.03746 0.987 0.776 1.26 PRS_PLINK_0.0199526231496888 FALSE 649.1 Diabetes or abnormal glucose tolerance complicating pregnancy Female 249 2433 12 pregnancy complications royalblue4 2433, 249 608, 73 608, 45 608, 59 608, 72 0.0381 0.0707 0.59 0.2291 1.04 0.904 1.19 -0.504 0.202 0.0125 1.903 0.604 0.407 0.897 -0.334 0.192 0.0822 1.085 0.716 0.491 1.04 0.0682 0.187 0.716 0.1451 1.07 0.742 1.55 PRS_PLINK_0.0199526231496888 FALSE 653 Problems associated with amniotic cavity and membranes Female 369 2814 12 pregnancy complications royalblue4 2814, 369 703, 85 703, 108 703, 91 704, 85 0.024 0.0577 0.678 0.169 1.02 0.915 1.15 0.25 0.154 0.106 0.9747 1.28 0.948 1.74 0.115 0.163 0.482 0.3169 1.12 0.815 1.54 0.123 0.17 0.47 0.3282 1.13 0.81 1.58 PRS_PLINK_0.0199526231496888 FALSE 654.1 Abnormality of organs and soft tissues of pelvis complicating pregnancy, childbirth, or the puerperium Female 118 1049 12 pregnancy complications royalblue4 1049, 118 263, 24 262, 30 262, 32 262, 32 0.181 0.0998 0.0693 1.159 1.2 0.986 1.46 0.265 0.284 0.352 0.4539 1.3 0.747 2.27 0.393 0.286 0.168 0.7741 1.48 0.847 2.59 0.537 0.298 0.0713 1.147 1.71 0.955 3.06 PRS_PLINK_0.0199526231496888 FALSE 654.2 Rhesus isoimmunization in pregnancy Female 120 1033 12 pregnancy complications royalblue4 1033, 120 259, 29 258, 22 258, 33 258, 36 0.135 0.0987 0.172 0.7639 1.14 0.943 1.39 -0.211 0.292 0.469 0.3292 0.809 0.457 1.43 0.185 0.271 0.495 0.3054 1.2 0.708 2.05 0.373 0.273 0.171 0.7663 1.45 0.851 2.48 PRS_PLINK_0.0199526231496888 FALSE 655 Known or suspected fetal abnormality affecting management of mother Female 943 4628 12 pregnancy complications royalblue4 4628, 943 1156, 226 1157, 245 1157, 233 1157, 239 0.0548 0.0376 0.145 0.8387 1.06 0.981 1.14 0.0925 0.103 0.367 0.4353 1.1 0.897 1.34 0.0321 0.105 0.759 0.1197 1.03 0.841 1.27 0.123 0.107 0.254 0.5958 1.13 0.916 1.4 PRS_PLINK_0.0199526231496888 FALSE 655.1 Abnormality in fetal heart rate or rhythm Female 358 2841 12 pregnancy complications royalblue4 2841, 358 710, 87 710, 97 710, 94 710, 80 0.048 0.059 0.416 0.3809 1.05 0.935 1.18 0.135 0.158 0.395 0.4035 1.14 0.839 1.56 0.0832 0.161 0.605 0.2181 1.09 0.793 1.49 0.0685 0.173 0.692 0.1598 1.07 0.763 1.5 PRS_PLINK_0.0199526231496888 FALSE 656 Other perinatal conditions of fetus or newborn Both 493 3401 12 pregnancy complications royalblue4 3401, 493 850, 117 850, 125 850, 120 850, 131 0.0899 0.0507 0.0765 1.117 1.09 0.99 1.21 0.092 0.139 0.507 0.2951 1.1 0.835 1.44 0.0408 0.142 0.774 0.1115 1.04 0.789 1.38 0.205 0.145 0.157 0.8044 1.23 0.924 1.63 PRS_PLINK_0.0199526231496888 FALSE 656.2 Respiratory conditions of fetus and newborn Both 14 172 12 pregnancy complications royalblue4 172, 14 43, 1 43, 3 43, 3 43, 7 0.475 0.313 0.129 0.8884 1.61 0.87 2.97 1.26 0.967 0.191 0.7196 3.54 0.533 23.6 0.552 1.02 0.587 0.2314 1.74 0.237 12.7 1.68 0.95 0.0775 1.111 5.35 0.831 34.4 PRS_PLINK_0.0199526231496888 TRUE 669 Complications of labor and delivery NEC Female 507 3531 12 pregnancy complications royalblue4 3531, 507 882, 128 883, 125 882, 117 883, 137 0.0817 0.0497 0.1 0.9987 1.09 0.984 1.2 0.00751 0.136 0.956 0.01962 1.01 0.772 1.31 -0.0682 0.139 0.625 0.2044 0.934 0.711 1.23 0.164 0.14 0.241 0.6179 1.18 0.896 1.55 PRS_PLINK_0.0199526231496888 FALSE 671 Venous/cerebrovascular complications embolism in pregnancy and the puerperium Female 107 986 12 pregnancy complications royalblue4 986, 107 247, 37 246, 23 246, 29 247, 18 -0.16 0.107 0.135 0.8698 0.852 0.691 1.05 -0.419 0.277 0.13 0.8851 0.658 0.382 1.13 -0.252 0.27 0.351 0.4552 0.777 0.458 1.32 -0.717 0.313 0.0221 1.656 0.488 0.264 0.902 PRS_PLINK_0.0199526231496888 FALSE 674 Other complications of the puerperium NEC Female 87 818 12 pregnancy complications royalblue4 818, 87 205, 18 204, 17 204, 26 205, 26 0.286 0.122 0.019 1.721 1.33 1.05 1.69 0.0262 0.346 0.94 0.02701 1.03 0.521 2.02 0.619 0.336 0.0653 1.185 1.86 0.961 3.59 0.678 0.347 0.0511 1.291 1.97 0.997 3.89 PRS_PLINK_0.0199526231496888 FALSE 676 Other disorders of the breast associated with childbirth and disorders of lactation Female 124 988 12 pregnancy complications royalblue4 988, 124 247, 38 247, 26 247, 36 247, 24 -0.112 0.0991 0.258 0.5883 0.894 0.736 1.09 -0.388 0.271 0.152 0.8187 0.679 0.399 1.15 0.00137 0.254 0.996 0.001878 1 0.609 1.65 -0.228 0.292 0.434 0.3625 0.796 0.449 1.41 PRS_PLINK_0.0199526231496888 FALSE 681 Superficial cellulitis and abscess Both 1731 10531 13 dermatologic firebrick 10531, 1731 2633, 429 2633, 423 2632, 417 2633, 461 0.051 0.0269 0.0577 1.239 1.05 0.998 1.11 -0.014 0.0746 0.851 0.06988 0.986 0.852 1.14 -0.0308 0.0759 0.685 0.1643 0.97 0.836 1.13 0.125 0.0765 0.101 0.9956 1.13 0.976 1.32 PRS_PLINK_0.0199526231496888 FALSE 681.1 Cellulitis and abscess of fingers/toes Both 309 2925 13 dermatologic firebrick 2925, 309 732, 79 731, 74 731, 68 731, 88 0.0529 0.0617 0.392 0.4067 1.05 0.934 1.19 -0.0904 0.171 0.597 0.2243 0.914 0.654 1.28 -0.134 0.175 0.446 0.3508 0.875 0.62 1.23 0.0741 0.171 0.664 0.1779 1.08 0.771 1.5 PRS_PLINK_0.0199526231496888 FALSE 681.2 Cellulitis and abscess of face/neck Both 238 2502 13 dermatologic firebrick 2502, 238 626, 52 625, 54 625, 71 626, 61 0.08 0.0698 0.252 0.5986 1.08 0.945 1.24 0.0537 0.2 0.788 0.1033 1.06 0.713 1.56 0.367 0.193 0.0572 1.243 1.44 0.989 2.11 0.198 0.208 0.342 0.4661 1.22 0.811 1.83 PRS_PLINK_0.0199526231496888 FALSE 681.3 Cellulitis and abscess of arm/hand Both 506 4931 13 dermatologic firebrick 4931, 506 1233, 118 1233, 124 1232, 125 1233, 139 0.0954 0.048 0.0467 1.331 1.1 1 1.21 0.0559 0.135 0.678 0.1691 1.06 0.812 1.38 0.0199 0.137 0.884 0.05345 1.02 0.781 1.33 0.197 0.137 0.152 0.8188 1.22 0.93 1.59 PRS_PLINK_0.0199526231496888 FALSE 681.5 Cellulitis and abscess of leg, except foot Both 515 5059 13 dermatologic firebrick 5059, 515 1265, 111 1265, 135 1264, 130 1265, 139 0.0984 0.0477 0.0391 1.408 1.1 1 1.21 0.203 0.134 0.13 0.886 1.23 0.942 1.59 0.119 0.137 0.385 0.4141 1.13 0.861 1.47 0.283 0.139 0.0419 1.378 1.33 1.01 1.74 PRS_PLINK_0.0199526231496888 FALSE 681.6 Cellulitis and abscess of foot, toe Both 410 4016 13 dermatologic firebrick 4016, 410 1004, 85 1004, 112 1004, 92 1004, 121 0.142 0.0538 0.00835 2.079 1.15 1.04 1.28 0.273 0.15 0.0699 1.155 1.31 0.978 1.76 0.0378 0.159 0.812 0.09057 1.04 0.761 1.42 0.386 0.155 0.0126 1.899 1.47 1.09 1.99 PRS_PLINK_0.0199526231496888 FALSE 681.7 Cellulitis and abscess of trunk Both 500 4202 13 dermatologic firebrick 4202, 500 1051, 132 1050, 112 1050, 112 1051, 143 0.0551 0.0485 0.255 0.5929 1.06 0.961 1.16 -0.177 0.136 0.191 0.7188 0.837 0.642 1.09 -0.17 0.138 0.216 0.666 0.843 0.644 1.1 0.122 0.134 0.363 0.4398 1.13 0.869 1.47 PRS_PLINK_0.0199526231496888 FALSE 686 Other local infections of skin and subcutaneous tissue Both 567 5546 13 dermatologic firebrick 5546, 567 1387, 156 1386, 151 1386, 105 1387, 154 -0.0525 0.0452 0.246 0.6092 0.949 0.868 1.04 -0.0386 0.12 0.749 0.1258 0.962 0.76 1.22 -0.425 0.134 0.0015 2.825 0.654 0.503 0.85 0.00913 0.126 0.942 0.02578 1.01 0.788 1.29 PRS_PLINK_0.0199526231496888 FALSE 686.1 Carbuncle and furuncle Both 146 1698 13 dermatologic firebrick 1698, 146 425, 38 424, 34 424, 32 425, 42 0.109 0.0878 0.215 0.6666 1.11 0.939 1.32 0.0288 0.248 0.908 0.04214 1.03 0.633 1.67 -0.0465 0.25 0.852 0.06937 0.955 0.585 1.56 0.181 0.247 0.465 0.3329 1.2 0.738 1.94 PRS_PLINK_0.0199526231496888 FALSE 686.2 Impetigo Both 138 1225 13 dermatologic firebrick 1225, 138 307, 31 306, 30 306, 37 306, 40 0.121 0.0938 0.198 0.7023 1.13 0.939 1.36 -0.0465 0.264 0.86 0.06529 0.955 0.569 1.6 0.111 0.254 0.661 0.1798 1.12 0.679 1.84 0.173 0.257 0.5 0.3009 1.19 0.719 1.97 PRS_PLINK_0.0199526231496888 FALSE 686.3 Pilonidal cyst Both 59 491 13 dermatologic firebrick 491, 59 123, 11 123, 15 122, 15 123, 18 0.153 0.143 0.287 0.5425 1.16 0.88 1.54 0.333 0.4 0.406 0.3914 1.39 0.636 3.06 0.377 0.408 0.355 0.4493 1.46 0.655 3.24 0.563 0.398 0.157 0.8045 1.76 0.805 3.83 PRS_PLINK_0.0199526231496888 FALSE 686.4 Pyogenic granuloma Both 38 431 13 dermatologic firebrick 431, 38 108, 12 108, 7 107, 8 108, 11 0.0596 0.174 0.732 0.1356 1.06 0.755 1.49 -0.468 0.483 0.333 0.4776 0.626 0.243 1.61 -0.382 0.45 0.396 0.4018 0.683 0.282 1.65 -0.192 0.479 0.688 0.1625 0.825 0.323 2.11 PRS_PLINK_0.0199526231496888 TRUE 686.5 Pyoderma Both 17 158 13 dermatologic firebrick 158, 17 40, 6 39, 3 39, 2 40, 6 0.0113 0.236 0.962 0.01689 1.01 0.637 1.61 -0.567 0.673 0.4 0.3981 0.567 0.152 2.12 -0.834 0.721 0.247 0.6071 0.434 0.106 1.78 0.0513 0.611 0.933 0.0301 1.05 0.318 3.49 PRS_PLINK_0.0199526231496888 TRUE 687 Symptoms affecting skin Both 472 4290 13 dermatologic firebrick 4290, 472 1073, 137 1072, 98 1072, 112 1073, 124 -0.0388 0.0503 0.44 0.3562 0.962 0.872 1.06 -0.353 0.139 0.0111 1.955 0.703 0.535 0.923 -0.18 0.136 0.187 0.7273 0.836 0.64 1.09 -0.0584 0.136 0.668 0.1751 0.943 0.722 1.23 PRS_PLINK_0.0199526231496888 FALSE 687.1 Rash and other nonspecific skin eruption Both 2030 9390 13 dermatologic firebrick 9390, 2030 2348, 552 2347, 491 2347, 501 2348, 485 -0.0463 0.0254 0.0688 1.162 0.955 0.908 1 -0.102 0.0693 0.142 0.8491 0.903 0.789 1.03 -0.0871 0.0701 0.214 0.669 0.917 0.799 1.05 -0.103 0.0729 0.157 0.8035 0.902 0.782 1.04 PRS_PLINK_0.0199526231496888 FALSE 687.3 Changes in skin texture Both 109 1024 13 dermatologic firebrick 1024, 109 256, 27 256, 19 256, 29 256, 34 0.0965 0.103 0.347 0.4592 1.1 0.901 1.35 -0.376 0.306 0.219 0.6592 0.687 0.377 1.25 0.0681 0.281 0.809 0.09229 1.07 0.617 1.86 0.186 0.286 0.516 0.2877 1.2 0.688 2.11 PRS_PLINK_0.0199526231496888 FALSE 687.4 Disturbance of skin sensation Both 1738 9278 13 dermatologic firebrick 9278, 1738 2320, 457 2319, 440 2319, 428 2320, 412 -0.0262 0.027 0.333 0.4774 0.974 0.924 1.03 -0.0403 0.0736 0.584 0.2336 0.961 0.832 1.11 -0.0646 0.075 0.389 0.4102 0.937 0.809 1.09 -0.0787 0.0777 0.311 0.5072 0.924 0.794 1.08 PRS_PLINK_0.0199526231496888 FALSE 689 Disorder of skin and subcutaneous tissue NOS Both 2362 10427 13 dermatologic firebrick 10427, 2362 2607, 609 2607, 599 2606, 609 2607, 544 -0.00941 0.0237 0.692 0.1599 0.991 0.946 1.04 0.0219 0.0649 0.736 0.1334 1.02 0.9 1.16 0.0414 0.0656 0.528 0.2776 1.04 0.917 1.19 -0.0732 0.0691 0.289 0.5385 0.929 0.812 1.06 PRS_PLINK_0.0199526231496888 FALSE 690 Erythematosquamous dermatosis Both 1136 8142 13 dermatologic firebrick 8142, 1136 2036, 335 2035, 266 2035, 287 2036, 248 -0.0889 0.033 0.00704 2.152 0.915 0.858 0.976 -0.186 0.089 0.0362 1.441 0.83 0.697 0.988 -0.116 0.0885 0.191 0.7186 0.891 0.749 1.06 -0.266 0.0942 0.00475 2.324 0.766 0.637 0.922 PRS_PLINK_0.0199526231496888 FALSE 690.1 Seborrheic dermatitis Both 1133 8135 13 dermatologic firebrick 8135, 1133 2034, 335 2034, 266 2033, 285 2034, 247 -0.091 0.033 0.00583 2.235 0.913 0.856 0.974 -0.187 0.089 0.0357 1.448 0.829 0.697 0.988 -0.123 0.0886 0.166 0.7809 0.884 0.743 1.05 -0.27 0.0943 0.00426 2.371 0.764 0.635 0.919 PRS_PLINK_0.0199526231496888 FALSE 691 Congenital anomalies of skin Both 182 1670 13 dermatologic firebrick 1670, 182 418, 51 417, 36 417, 54 418, 41 -0.0141 0.0789 0.858 0.06658 0.986 0.845 1.15 -0.292 0.226 0.197 0.7051 0.747 0.479 1.16 0.0377 0.21 0.857 0.06687 1.04 0.688 1.57 -0.209 0.226 0.355 0.45 0.811 0.521 1.26 PRS_PLINK_0.0199526231496888 FALSE 691.3 Congenital pigmentary anomalies of skin Both 31 205 13 dermatologic firebrick 205, 31 52, 7 51, 6 51, 8 51, 10 0.263 0.204 0.198 0.7025 1.3 0.871 1.94 -0.544 0.61 0.373 0.4285 0.581 0.176 1.92 0.0449 0.561 0.936 0.02861 1.05 0.348 3.14 0.218 0.524 0.677 0.1692 1.24 0.445 3.48 PRS_PLINK_0.0199526231496888 TRUE 694 Dyschromia and Vitiligo Both 496 4715 13 dermatologic firebrick 4715, 496 1179, 139 1179, 126 1178, 116 1179, 115 -0.0655 0.0484 0.176 0.7537 0.937 0.852 1.03 -0.106 0.13 0.416 0.3805 0.9 0.697 1.16 -0.169 0.134 0.209 0.6794 0.845 0.649 1.1 -0.241 0.138 0.081 1.091 0.786 0.6 1.03 PRS_PLINK_0.0199526231496888 FALSE 694.1 Vitiligo Both 38 353 13 dermatologic firebrick 353, 38 89, 9 88, 6 88, 13 88, 10 0.1 0.171 0.558 0.2532 1.11 0.791 1.54 -0.264 0.526 0.615 0.2108 0.768 0.274 2.15 0.411 0.462 0.373 0.428 1.51 0.61 3.73 0.39 0.497 0.433 0.3638 1.48 0.558 3.91 PRS_PLINK_0.0199526231496888 TRUE 694.2 Other dyschromia Both 439 4252 13 dermatologic firebrick 4252, 439 1063, 126 1063, 113 1063, 101 1063, 99 -0.087 0.0514 0.0907 1.042 0.917 0.829 1.01 -0.11 0.137 0.423 0.3738 0.896 0.686 1.17 -0.219 0.142 0.124 0.9074 0.803 0.608 1.06 -0.321 0.147 0.0288 1.541 0.725 0.544 0.967 PRS_PLINK_0.0199526231496888 FALSE 694.3 Vascular disorders of skin Both 27 206 13 dermatologic firebrick 206, 27 52, 7 51, 5 51, 6 52, 9 0.125 0.19 0.511 0.2917 1.13 0.781 1.64 -0.314 0.581 0.589 0.2298 0.73 0.234 2.28 0.00296 0.584 0.996 0.001763 1 0.319 3.15 0.26 0.567 0.647 0.1893 1.3 0.427 3.94 PRS_PLINK_0.0199526231496888 TRUE 695 Erythematous conditions Both 1078 8444 13 dermatologic firebrick 8444, 1078 2111, 281 2111, 264 2111, 268 2111, 264 -0.0333 0.0334 0.319 0.496 0.967 0.906 1.03 -0.0511 0.0917 0.578 0.2384 0.95 0.794 1.14 -0.0393 0.0926 0.672 0.1728 0.962 0.802 1.15 -0.0743 0.0957 0.438 0.3589 0.928 0.77 1.12 PRS_PLINK_0.0199526231496888 FALSE 695.1 Toxic erythema Both 20 215 13 dermatologic firebrick 215, 20 54, 5 54, 8 53, 6 54, 1 -0.5 0.257 0.0518 1.286 0.607 0.367 1 0.361 0.563 0.521 0.2832 1.44 0.476 4.32 -0.112 0.614 0.855 0.06803 0.894 0.269 2.98 -1.5 0.918 0.101 0.9951 0.222 0.0368 1.34 PRS_PLINK_0.0199526231496888 TRUE 695.2 Bullous dermatoses Both 23 172 13 dermatologic firebrick 172, 23 43, 7 43, 4 43, 7 43, 5 -0.0929 0.21 0.659 0.1814 0.911 0.603 1.38 -0.368 0.604 0.542 0.2658 0.692 0.212 2.26 0.248 0.592 0.675 0.1706 1.28 0.402 4.09 -0.425 0.621 0.494 0.3063 0.654 0.194 2.21 PRS_PLINK_0.0199526231496888 TRUE 695.3 Rosacea Both 435 4589 13 dermatologic firebrick 4589, 435 1148, 122 1147, 113 1147, 106 1147, 94 -0.0661 0.0515 0.199 0.7001 0.936 0.846 1.04 -0.0761 0.137 0.579 0.2371 0.927 0.708 1.21 -0.138 0.14 0.326 0.4869 0.871 0.662 1.15 -0.249 0.148 0.0911 1.041 0.779 0.584 1.04 PRS_PLINK_0.0199526231496888 FALSE 695.4 Lupus (localized and systemic) Both 225 2051 13 dermatologic firebrick 2051, 225 513, 50 513, 51 512, 70 513, 53 -0.0306 0.0719 0.671 0.1735 0.97 0.842 1.12 0.0151 0.207 0.942 0.02601 1.02 0.677 1.52 0.324 0.197 0.1 0.9995 1.38 0.94 2.03 -0.0296 0.213 0.89 0.05082 0.971 0.639 1.47 PRS_PLINK_0.0199526231496888 FALSE 695.41 Cutaneous lupus erythematosus Both 80 804 13 dermatologic firebrick 804, 80 201, 16 201, 22 201, 23 201, 18 -0.0773 0.117 0.51 0.2923 0.926 0.736 1.16 0.316 0.33 0.339 0.4703 1.37 0.718 2.62 0.373 0.332 0.261 0.584 1.45 0.758 2.79 0.12 0.355 0.735 0.1338 1.13 0.563 2.26 PRS_PLINK_0.0199526231496888 FALSE 695.42 Systemic lupus erythematosus Both 219 1932 13 dermatologic firebrick 1932, 219 483, 50 483, 48 483, 67 483, 53 -0.0277 0.0728 0.704 0.1525 0.973 0.843 1.12 -0.0483 0.21 0.818 0.08733 0.953 0.632 1.44 0.293 0.2 0.143 0.8436 1.34 0.906 1.98 -0.0412 0.213 0.847 0.07234 0.96 0.632 1.46 PRS_PLINK_0.0199526231496888 FALSE 695.7 Prurigo and Lichen Both 128 1534 13 dermatologic firebrick 1534, 128 384, 35 383, 29 383, 32 384, 32 -0.0848 0.0969 0.381 0.4188 0.919 0.76 1.11 -0.183 0.26 0.48 0.3184 0.832 0.5 1.39 -0.197 0.259 0.448 0.3486 0.822 0.494 1.37 -0.276 0.268 0.302 0.5202 0.758 0.449 1.28 PRS_PLINK_0.0199526231496888 FALSE 695.8 Other specified erythematous conditions Both 213 2079 13 dermatologic firebrick 2079, 213 520, 54 520, 46 519, 49 520, 64 0.0712 0.076 0.349 0.4574 1.07 0.925 1.25 -0.139 0.207 0.504 0.2979 0.871 0.58 1.31 -0.0373 0.208 0.858 0.06672 0.963 0.641 1.45 0.199 0.205 0.33 0.4812 1.22 0.817 1.82 PRS_PLINK_0.0199526231496888 FALSE 695.81 Erythema nodosum Both 28 191 13 dermatologic firebrick 191, 28 48, 9 48, 2 47, 7 48, 10 0.0545 0.217 0.802 0.09598 1.06 0.69 1.62 -0.874 0.684 0.201 0.6961 0.417 0.109 1.59 0.151 0.575 0.792 0.1011 1.16 0.377 3.59 0.252 0.521 0.629 0.2014 1.29 0.463 3.57 PRS_PLINK_0.0199526231496888 TRUE 695.9 Unspecified erythematous condition Both 172 1727 13 dermatologic firebrick 1727, 172 432, 43 432, 45 431, 34 432, 49 0.0387 0.0812 0.634 0.198 1.04 0.886 1.22 0.0234 0.224 0.917 0.03776 1.02 0.66 1.59 -0.335 0.241 0.164 0.7842 0.715 0.446 1.15 0.0203 0.23 0.93 0.03166 1.02 0.65 1.6 PRS_PLINK_0.0199526231496888 FALSE 696 Psoriasis and related disorders Both 359 3730 13 dermatologic firebrick 3730, 359 933, 90 932, 83 932, 99 933, 87 0.0357 0.0571 0.532 0.274 1.04 0.927 1.16 -0.0602 0.159 0.705 0.1521 0.942 0.69 1.29 0.131 0.155 0.399 0.3994 1.14 0.841 1.55 -0.0251 0.165 0.879 0.05596 0.975 0.706 1.35 PRS_PLINK_0.0199526231496888 FALSE 696.3 Pityriasis Both 33 325 13 dermatologic firebrick 325, 33 82, 7 81, 11 81, 9 81, 6 -0.0716 0.2 0.721 0.1423 0.931 0.629 1.38 0.445 0.473 0.346 0.4604 1.56 0.618 3.94 0.0457 0.52 0.93 0.03155 1.05 0.378 2.9 -0.587 0.608 0.334 0.4756 0.556 0.169 1.83 PRS_PLINK_0.0199526231496888 TRUE 696.4 Psoriasis Both 327 3442 13 dermatologic firebrick 3442, 327 861, 84 860, 76 860, 84 861, 83 0.0322 0.0596 0.59 0.2294 1.03 0.919 1.16 -0.0901 0.164 0.584 0.2336 0.914 0.662 1.26 0.0602 0.164 0.714 0.1461 1.06 0.769 1.47 0.0252 0.17 0.883 0.05419 1.03 0.734 1.43 PRS_PLINK_0.0199526231496888 FALSE 696.41 Psoriasis vulgaris Both 302 3157 13 dermatologic firebrick 3157, 302 790, 76 789, 71 789, 81 789, 74 0.0303 0.0619 0.625 0.2044 1.03 0.913 1.16 -0.0552 0.172 0.748 0.1261 0.946 0.676 1.32 0.124 0.17 0.467 0.3311 1.13 0.811 1.58 0.00277 0.18 0.988 0.005361 1 0.705 1.43 PRS_PLINK_0.0199526231496888 FALSE 696.42 Psoriatic arthropathy Both 67 693 13 dermatologic firebrick 693, 67 174, 19 173, 13 173, 18 173, 17 0.0606 0.124 0.624 0.2046 1.06 0.834 1.35 -0.306 0.366 0.402 0.3953 0.736 0.36 1.51 0.107 0.356 0.763 0.1176 1.11 0.555 2.24 0.112 0.353 0.75 0.1248 1.12 0.56 2.24 PRS_PLINK_0.0199526231496888 FALSE 697 Sarcoidosis Both 99 837 13 dermatologic firebrick 837, 99 210, 19 209, 26 209, 27 209, 26 0.00215 0.108 0.984 0.006979 1 0.811 1.24 0.298 0.312 0.34 0.4687 1.35 0.731 2.48 0.354 0.315 0.26 0.5845 1.43 0.769 2.64 0.298 0.326 0.36 0.4433 1.35 0.712 2.55 PRS_PLINK_0.0199526231496888 FALSE 698 Pruritus and related conditions Both 725 6557 13 dermatologic firebrick 6557, 725 1639, 211 1639, 181 1639, 157 1639, 176 -0.0463 0.0407 0.255 0.5931 0.955 0.881 1.03 -0.134 0.108 0.214 0.6691 0.875 0.709 1.08 -0.293 0.113 0.00937 2.028 0.746 0.598 0.931 -0.144 0.113 0.203 0.6931 0.866 0.693 1.08 PRS_PLINK_0.0199526231496888 FALSE 700 Corns and callosities Both 283 2579 13 dermatologic firebrick 2579, 283 645, 65 645, 66 644, 76 645, 76 0.083 0.0672 0.217 0.6639 1.09 0.952 1.24 -0.000409 0.185 0.998 0.0007678 1 0.696 1.44 0.159 0.182 0.384 0.4156 1.17 0.82 1.67 0.118 0.188 0.529 0.2763 1.13 0.779 1.63 PRS_PLINK_0.0199526231496888 FALSE 701 Other hypertrophic and atrophic conditions of skin Both 1966 10616 13 dermatologic firebrick 10616, 1966 2653, 510 2654, 503 2654, 503 2654, 450 -0.0352 0.0255 0.168 0.7736 0.965 0.918 1.01 -0.00917 0.0696 0.895 0.0481 0.991 0.865 1.14 -0.0125 0.0707 0.859 0.06581 0.988 0.86 1.13 -0.12 0.0744 0.108 0.9669 0.887 0.767 1.03 PRS_PLINK_0.0199526231496888 FALSE 701.1 Keratoderma, acquired Both 139 1305 13 dermatologic firebrick 1305, 139 327, 36 326, 36 326, 35 326, 32 -0.0243 0.0902 0.787 0.1039 0.976 0.818 1.16 -0.0256 0.246 0.917 0.03757 0.975 0.602 1.58 -0.0455 0.251 0.856 0.06735 0.956 0.584 1.56 -0.247 0.26 0.343 0.4651 0.781 0.469 1.3 PRS_PLINK_0.0199526231496888 FALSE 701.2 Scar conditions and fibrosis of skin Both 563 5942 13 dermatologic firebrick 5942, 563 1485, 133 1485, 154 1485, 154 1486, 122 -0.0314 0.0457 0.492 0.3082 0.969 0.886 1.06 0.147 0.124 0.236 0.6274 1.16 0.908 1.48 0.161 0.125 0.2 0.6998 1.17 0.919 1.5 -0.0644 0.137 0.638 0.1955 0.938 0.717 1.23 PRS_PLINK_0.0199526231496888 FALSE 701.3 Circumscribed scleroderma Both 148 1518 13 dermatologic firebrick 1518, 148 380, 35 379, 41 379, 37 380, 35 -0.0562 0.0879 0.522 0.2823 0.945 0.796 1.12 0.155 0.238 0.514 0.2889 1.17 0.733 1.86 0.0551 0.247 0.823 0.08454 1.06 0.652 1.71 -0.0965 0.256 0.707 0.1509 0.908 0.55 1.5 PRS_PLINK_0.0199526231496888 FALSE 701.4 Keloid scar Both 165 1836 13 dermatologic firebrick 1836, 165 458, 36 459, 54 459, 44 459, 31 -0.0578 0.0851 0.497 0.3035 0.944 0.799 1.12 0.363 0.224 0.105 0.9785 1.44 0.927 2.23 0.139 0.236 0.557 0.2538 1.15 0.723 1.83 -0.244 0.265 0.357 0.4468 0.784 0.467 1.32 PRS_PLINK_0.0199526231496888 FALSE 701.5 Abnormal granulation tissue Both 119 1025 13 dermatologic firebrick 1025, 119 256, 35 256, 21 256, 34 256, 29 -0.00668 0.0949 0.944 0.02506 0.993 0.825 1.2 -0.4 0.287 0.163 0.7883 0.67 0.382 1.18 -0.00744 0.256 0.977 0.0102 0.993 0.601 1.64 -0.213 0.271 0.432 0.3647 0.808 0.475 1.38 PRS_PLINK_0.0199526231496888 FALSE 702 Degenerative skin conditions and other dermatoses Both 1491 7717 13 dermatologic firebrick 7717, 1491 1929, 416 1929, 363 1929, 374 1929, 338 -0.0358 0.0297 0.228 0.6413 0.965 0.91 1.02 -0.0751 0.0812 0.355 0.4499 0.928 0.791 1.09 -0.0505 0.0818 0.537 0.2702 0.951 0.81 1.12 -0.15 0.0858 0.0798 1.098 0.86 0.727 1.02 PRS_PLINK_0.0199526231496888 FALSE 702.1 Actinic keratosis Both 829 5922 13 dermatologic firebrick 5922, 829 1481, 240 1480, 202 1480, 203 1481, 184 -0.0716 0.0384 0.0617 1.209 0.931 0.863 1 -0.128 0.104 0.217 0.6633 0.88 0.718 1.08 -0.171 0.105 0.103 0.9859 0.843 0.687 1.04 -0.233 0.11 0.0349 1.457 0.792 0.638 0.984 PRS_PLINK_0.0199526231496888 FALSE 702.2 Seborrheic keratosis Both 1152 7907 13 dermatologic firebrick 7907, 1152 1977, 336 1977, 279 1976, 290 1977, 247 -0.0789 0.0328 0.0162 1.791 0.924 0.867 0.986 -0.14 0.0886 0.115 0.9385 0.87 0.731 1.03 -0.122 0.0889 0.169 0.7719 0.885 0.743 1.05 -0.269 0.0949 0.0046 2.338 0.764 0.635 0.92 PRS_PLINK_0.0199526231496888 FALSE 702.4 Degenerative skin disorders Both 29 243 13 dermatologic firebrick 243, 29 61, 4 61, 10 60, 6 61, 9 0.0726 0.204 0.722 0.1415 1.08 0.721 1.6 0.819 0.577 0.156 0.8076 2.27 0.732 7.03 0.54 0.643 0.401 0.3968 1.72 0.486 6.06 0.908 0.638 0.154 0.8114 2.48 0.711 8.66 PRS_PLINK_0.0199526231496888 TRUE 703 Diseases of nail, NOS Both 377 3593 13 dermatologic firebrick 3593, 377 899, 97 898, 90 898, 89 898, 101 0.0337 0.056 0.547 0.2623 1.03 0.927 1.15 -0.0677 0.153 0.659 0.1814 0.934 0.692 1.26 -0.0229 0.157 0.884 0.05365 0.977 0.719 1.33 0.129 0.158 0.415 0.3818 1.14 0.834 1.55 PRS_PLINK_0.0199526231496888 FALSE 703.1 Ingrowing nail Both 210 2264 13 dermatologic firebrick 2264, 210 566, 56 566, 51 566, 49 566, 54 0.00169 0.0761 0.982 0.007757 1 0.863 1.16 -0.134 0.204 0.51 0.2922 0.874 0.586 1.3 -0.0604 0.207 0.77 0.1134 0.941 0.628 1.41 0.00395 0.207 0.985 0.006641 1 0.668 1.51 PRS_PLINK_0.0199526231496888 FALSE 704 Diseases of hair and hair follicles Both 942 8778 13 dermatologic firebrick 8778, 942 2194, 233 2194, 258 2194, 223 2195, 228 -0.0104 0.0357 0.771 0.1128 0.99 0.923 1.06 0.0994 0.0957 0.299 0.5246 1.1 0.916 1.33 -0.0469 0.1 0.64 0.194 0.954 0.784 1.16 0.00734 0.103 0.943 0.02537 1.01 0.823 1.23 PRS_PLINK_0.0199526231496888 FALSE 704.1 Alopecia Both 497 4538 13 dermatologic firebrick 4538, 497 1134, 125 1134, 139 1134, 102 1135, 131 -0.0282 0.0496 0.569 0.2449 0.972 0.882 1.07 0.0905 0.13 0.487 0.3122 1.09 0.848 1.41 -0.188 0.142 0.184 0.7358 0.829 0.628 1.09 0.119 0.138 0.389 0.4099 1.13 0.859 1.48 PRS_PLINK_0.0199526231496888 FALSE 704.11 Alopecia Areata Both 29 227 13 dermatologic firebrick 227, 29 57, 7 57, 6 56, 8 57, 8 0.0279 0.195 0.886 0.05235 1.03 0.701 1.51 -0.382 0.568 0.501 0.3 0.682 0.224 2.08 0.213 0.523 0.684 0.1652 1.24 0.444 3.45 0.142 0.538 0.792 0.1015 1.15 0.401 3.31 PRS_PLINK_0.0199526231496888 TRUE 704.12 Telogen effluvium Both 28 224 13 dermatologic firebrick 224, 28 56, 7 56, 12 56, 5 56, 4 -0.192 0.217 0.378 0.4223 0.826 0.539 1.26 0.605 0.513 0.238 0.6228 1.83 0.67 5.01 -0.278 0.584 0.634 0.1976 0.758 0.241 2.38 -0.641 0.735 0.383 0.4171 0.527 0.125 2.22 PRS_PLINK_0.0199526231496888 TRUE 704.2 Hirsutism Both 99 1230 13 dermatologic firebrick 1230, 99 308, 25 307, 24 307, 24 308, 26 0.109 0.109 0.319 0.4961 1.11 0.9 1.38 -0.12 0.295 0.685 0.1643 0.887 0.498 1.58 -0.106 0.304 0.726 0.1388 0.899 0.495 1.63 0.0954 0.302 0.752 0.1238 1.1 0.609 1.99 PRS_PLINK_0.0199526231496888 FALSE 704.8 Other specified diseases of hair and hair follicles Both 477 4837 13 dermatologic firebrick 4837, 477 1209, 117 1209, 137 1209, 118 1209, 105 -0.0437 0.0494 0.377 0.4235 0.957 0.869 1.05 0.153 0.132 0.248 0.6051 1.16 0.899 1.51 -0.0277 0.138 0.841 0.07502 0.973 0.742 1.28 -0.143 0.147 0.331 0.4807 0.866 0.649 1.16 PRS_PLINK_0.0199526231496888 FALSE 705 Disorders of sweat glands Both 192 2097 13 dermatologic firebrick 2097, 192 524, 46 524, 48 524, 45 524, 53 0.02 0.0781 0.798 0.0981 1.02 0.875 1.19 0.0599 0.214 0.78 0.1081 1.06 0.698 1.61 -0.0217 0.221 0.922 0.03537 0.979 0.634 1.51 0.11 0.219 0.615 0.2111 1.12 0.727 1.71 PRS_PLINK_0.0199526231496888 FALSE 705.1 Dyshidrosis Both 46 454 13 dermatologic firebrick 454, 46 114, 11 113, 17 113, 4 114, 14 -0.0376 0.153 0.807 0.09337 0.963 0.713 1.3 0.472 0.391 0.226 0.6451 1.6 0.746 3.45 -0.891 0.532 0.0936 1.029 0.41 0.145 1.16 0.142 0.42 0.734 0.134 1.15 0.506 2.63 PRS_PLINK_0.0199526231496888 TRUE 705.3 Hidradenitis Both 81 925 13 dermatologic firebrick 925, 81 232, 22 231, 13 231, 22 231, 24 0.0874 0.118 0.461 0.3368 1.09 0.865 1.38 -0.561 0.349 0.108 0.9678 0.57 0.288 1.13 -0.113 0.323 0.726 0.1393 0.893 0.474 1.68 0.0125 0.326 0.969 0.01346 1.01 0.535 1.92 PRS_PLINK_0.0199526231496888 FALSE 705.8 Hyperhidrosis Both 322 3188 13 dermatologic firebrick 3188, 322 796, 74 797, 83 797, 97 797, 68 -0.0195 0.0598 0.745 0.128 0.981 0.872 1.1 0.118 0.168 0.482 0.3171 1.13 0.81 1.56 0.292 0.165 0.0758 1.121 1.34 0.97 1.85 -0.0761 0.181 0.674 0.1714 0.927 0.65 1.32 PRS_PLINK_0.0199526231496888 FALSE 706 Diseases of sebaceous glands Both 1798 10718 13 dermatologic firebrick 10718, 1798 2679, 484 2679, 454 2679, 443 2680, 417 -0.0394 0.0267 0.14 0.8542 0.961 0.912 1.01 -0.0606 0.0719 0.399 0.3992 0.941 0.817 1.08 -0.0882 0.0732 0.228 0.6414 0.916 0.793 1.06 -0.147 0.0766 0.0549 1.26 0.863 0.743 1 PRS_PLINK_0.0199526231496888 FALSE 706.1 Acne Both 1044 7426 13 dermatologic firebrick 7426, 1044 1856, 279 1856, 268 1856, 264 1857, 233 -0.0403 0.0347 0.245 0.6102 0.96 0.897 1.03 -0.0437 0.0927 0.638 0.1955 0.957 0.798 1.15 -0.0341 0.0943 0.718 0.1442 0.966 0.803 1.16 -0.166 0.0997 0.0955 1.02 0.847 0.696 1.03 PRS_PLINK_0.0199526231496888 FALSE 706.2 Sebaceous cyst Both 721 6957 13 dermatologic firebrick 6957, 721 1739, 215 1739, 169 1739, 167 1739, 170 -0.0792 0.0404 0.0503 1.298 0.924 0.853 1 -0.233 0.109 0.0316 1.501 0.792 0.64 0.98 -0.251 0.11 0.0226 1.645 0.778 0.626 0.965 -0.224 0.113 0.0483 1.316 0.8 0.64 0.998 PRS_PLINK_0.0199526231496888 FALSE 706.3 Seborrhea Both 15 164 13 dermatologic firebrick 164, 15 41, 4 41, 3 41, 4 41, 4 0.125 0.272 0.646 0.1899 1.13 0.665 1.93 -0.116 0.74 0.875 0.05788 0.89 0.209 3.8 -0.039 0.726 0.957 0.01903 0.962 0.232 3.99 0.0258 0.743 0.972 0.0122 1.03 0.239 4.4 PRS_PLINK_0.0199526231496888 TRUE 706.8 Other specified diseases of sebaceous glands Both 356 3460 13 dermatologic firebrick 3460, 356 864, 94 865, 95 865, 76 865, 91 -0.0397 0.0574 0.489 0.3108 0.961 0.859 1.08 0.000359 0.153 0.998 0.0008153 1 0.742 1.35 -0.214 0.162 0.186 0.7297 0.808 0.588 1.11 -0.0741 0.16 0.644 0.1913 0.929 0.678 1.27 PRS_PLINK_0.0199526231496888 FALSE 707 Chronic ulcer of skin Both 782 6361 13 dermatologic firebrick 6361, 782 1591, 168 1590, 212 1590, 191 1590, 210 0.105 0.0389 0.00691 2.16 1.11 1.03 1.2 0.239 0.11 0.0295 1.53 1.27 1.02 1.57 0.129 0.114 0.256 0.592 1.14 0.911 1.42 0.233 0.115 0.0419 1.378 1.26 1.01 1.58 PRS_PLINK_0.0199526231496888 FALSE 707.1 Decubitus ulcer Both 279 1665 13 dermatologic firebrick 1665, 279 417, 56 416, 78 416, 75 416, 70 0.0772 0.0665 0.246 0.6091 1.08 0.948 1.23 0.347 0.189 0.0656 1.183 1.42 0.978 2.05 0.275 0.196 0.16 0.7947 1.32 0.897 1.93 0.225 0.202 0.265 0.5765 1.25 0.843 1.86 PRS_PLINK_0.0199526231496888 FALSE 707.2 Chronic ulcer of leg or foot Both 230 2070 13 dermatologic firebrick 2070, 230 518, 46 517, 46 517, 63 518, 75 0.253 0.0694 0.000266 3.576 1.29 1.12 1.48 0.0415 0.217 0.848 0.07159 1.04 0.682 1.59 0.314 0.209 0.133 0.8775 1.37 0.909 2.06 0.507 0.208 0.0146 1.837 1.66 1.11 2.5 PRS_PLINK_0.0199526231496888 FALSE 707.3 Chronic ulcer of unspecified site Both 459 4000 13 dermatologic firebrick 4000, 459 1000, 105 1000, 125 1000, 106 1000, 122 0.0755 0.0506 0.136 0.8679 1.08 0.977 1.19 0.168 0.14 0.23 0.6383 1.18 0.899 1.55 0.0209 0.146 0.887 0.05229 1.02 0.767 1.36 0.149 0.147 0.311 0.5068 1.16 0.87 1.55 PRS_PLINK_0.0199526231496888 FALSE 709 Diffuse diseases of connective tissue Both 449 4110 13 dermatologic firebrick 4110, 449 1028, 116 1027, 109 1027, 104 1028, 119 0.0139 0.0508 0.785 0.1051 1.01 0.918 1.12 -0.0243 0.141 0.863 0.06415 0.976 0.741 1.29 -0.0743 0.144 0.605 0.2184 0.928 0.701 1.23 0.07 0.144 0.626 0.2032 1.07 0.809 1.42 PRS_PLINK_0.0199526231496888 FALSE 709.2 Sicca syndrome Both 149 1324 13 dermatologic firebrick 1324, 149 331, 40 331, 41 331, 34 331, 33 -0.107 0.0895 0.232 0.634 0.899 0.754 1.07 0.0403 0.234 0.863 0.06402 1.04 0.659 1.65 -0.151 0.246 0.539 0.2684 0.86 0.531 1.39 -0.0279 0.254 0.913 0.03967 0.973 0.591 1.6 PRS_PLINK_0.0199526231496888 FALSE 709.3 Systemic sclerosis Both 76 643 13 dermatologic firebrick 643, 76 161, 25 161, 13 160, 19 161, 18 -0.0833 0.12 0.487 0.3126 0.92 0.727 1.16 -0.562 0.354 0.112 0.9522 0.57 0.285 1.14 -0.114 0.324 0.724 0.1402 0.892 0.473 1.68 -0.198 0.343 0.563 0.2493 0.82 0.419 1.61 PRS_PLINK_0.0199526231496888 FALSE 709.5 Dermatomyositis Both 20 221 13 dermatologic firebrick 221, 20 56, 5 55, 1 55, 6 55, 8 0.0612 0.234 0.794 0.1003 1.06 0.672 1.68 -1.05 0.799 0.189 0.7242 0.35 0.0731 1.67 -0.0225 0.595 0.97 0.01329 0.978 0.304 3.14 0.314 0.602 0.602 0.2207 1.37 0.421 4.45 PRS_PLINK_0.0199526231496888 TRUE 709.6 Other specified diffuse diseases of connective tissue Both 33 293 13 dermatologic firebrick 293, 33 74, 7 73, 10 73, 4 73, 11 -0.139 0.166 0.405 0.3929 0.87 0.628 1.21 0.163 0.517 0.753 0.1232 1.18 0.427 3.24 -0.435 0.623 0.485 0.3143 0.647 0.191 2.19 0.418 0.524 0.426 0.3711 1.52 0.543 4.24 PRS_PLINK_0.0199526231496888 TRUE 709.7 Unspecified diffuse connective tissue disease Both 292 2650 13 dermatologic firebrick 2650, 292 663, 76 662, 71 662, 70 663, 74 -0.00687 0.0623 0.912 0.03985 0.993 0.879 1.12 -0.0327 0.174 0.851 0.07019 0.968 0.688 1.36 -0.0839 0.176 0.634 0.1976 0.92 0.651 1.3 -0.0608 0.181 0.736 0.1329 0.941 0.66 1.34 PRS_PLINK_0.0199526231496888 FALSE 710 Osteomyelitis, periostitis, and other infections involving bone Both 318 2765 14 musculoskeletal darkolivegreen 2765, 318 692, 66 691, 77 691, 90 691, 85 0.095 0.0596 0.111 0.9554 1.1 0.978 1.24 0.199 0.176 0.26 0.5857 1.22 0.864 1.72 0.367 0.174 0.0353 1.453 1.44 1.03 2.03 0.265 0.179 0.139 0.8577 1.3 0.918 1.85 PRS_PLINK_0.0199526231496888 FALSE 710.1 Osteomyelitis Both 299 2653 14 musculoskeletal darkolivegreen 2653, 299 664, 64 663, 71 663, 85 663, 79 0.0934 0.0611 0.126 0.8993 1.1 0.974 1.24 0.159 0.181 0.381 0.4194 1.17 0.822 1.67 0.33 0.178 0.0635 1.197 1.39 0.982 1.97 0.199 0.183 0.276 0.5599 1.22 0.853 1.75 PRS_PLINK_0.0199526231496888 FALSE 710.11 Acute osteomyelitis Both 139 1293 14 musculoskeletal darkolivegreen 1293, 139 324, 30 323, 31 323, 36 323, 42 0.139 0.0871 0.11 0.9575 1.15 0.969 1.36 0.0484 0.263 0.854 0.06864 1.05 0.627 1.76 0.238 0.267 0.372 0.4298 1.27 0.752 2.14 0.331 0.261 0.204 0.6898 1.39 0.835 2.32 PRS_PLINK_0.0199526231496888 FALSE 710.12 Chronic osteomyelitis Both 135 1119 14 musculoskeletal darkolivegreen 1119, 135 280, 26 280, 37 279, 31 280, 41 0.176 0.0915 0.0548 1.262 1.19 0.996 1.43 0.387 0.267 0.147 0.8335 1.47 0.873 2.48 0.231 0.279 0.407 0.3904 1.26 0.73 2.18 0.395 0.271 0.145 0.8385 1.48 0.873 2.52 PRS_PLINK_0.0199526231496888 FALSE 710.19 Unspecified osteomyelitis Both 289 2522 14 musculoskeletal darkolivegreen 2522, 289 631, 62 630, 70 630, 82 631, 75 0.075 0.0624 0.23 0.6391 1.08 0.954 1.22 0.16 0.183 0.381 0.4191 1.17 0.82 1.68 0.311 0.181 0.0861 1.065 1.36 0.957 1.95 0.167 0.186 0.369 0.4329 1.18 0.821 1.7 PRS_PLINK_0.0199526231496888 FALSE 711 Arthropathy associated with infections Both 114 918 14 musculoskeletal darkolivegreen 918, 114 230, 28 229, 25 229, 21 230, 40 0.137 0.0982 0.162 0.7892 1.15 0.946 1.39 -0.0599 0.286 0.834 0.07885 0.942 0.538 1.65 -0.203 0.305 0.506 0.2963 0.816 0.449 1.48 0.508 0.282 0.0716 1.145 1.66 0.956 2.89 PRS_PLINK_0.0199526231496888 FALSE 711.1 Pyogenic arthritis Both 78 612 14 musculoskeletal darkolivegreen 612, 78 153, 19 153, 16 153, 15 153, 28 0.138 0.116 0.236 0.6279 1.15 0.914 1.44 -0.118 0.352 0.737 0.1328 0.888 0.446 1.77 -0.166 0.359 0.643 0.1918 0.847 0.419 1.71 0.356 0.326 0.274 0.563 1.43 0.755 2.7 PRS_PLINK_0.0199526231496888 FALSE 712 Infective connective tissue disorders Both 57 459 14 musculoskeletal darkolivegreen 459, 57 115, 14 115, 11 114, 20 115, 12 0.106 0.14 0.447 0.3494 1.11 0.846 1.46 -0.0932 0.413 0.821 0.08548 0.911 0.406 2.05 0.346 0.373 0.353 0.4516 1.41 0.681 2.93 0.0216 0.421 0.959 0.01816 1.02 0.448 2.33 PRS_PLINK_0.0199526231496888 FALSE 713 Arthropathy associated with other disorders classified elsewhere Both 68 808 14 musculoskeletal darkolivegreen 808, 68 202, 16 202, 18 202, 14 202, 20 0.11 0.125 0.381 0.4194 1.12 0.873 1.43 0.103 0.351 0.77 0.1135 1.11 0.557 2.2 0.14 0.38 0.712 0.1474 1.15 0.546 2.42 0.148 0.364 0.684 0.1649 1.16 0.569 2.36 PRS_PLINK_0.0199526231496888 FALSE 713.5 Arthropathy associated with neurological disorders Both 20 377 14 musculoskeletal darkolivegreen 377, 20 95, 4 94, 8 94, 4 94, 4 0.0875 0.212 0.679 0.1681 1.09 0.721 1.65 0.619 0.568 0.276 0.5588 1.86 0.61 5.65 0.194 0.642 0.763 0.1178 1.21 0.345 4.28 0.269 0.651 0.679 0.168 1.31 0.365 4.69 PRS_PLINK_0.0199526231496888 TRUE 714 Rheumatoid arthritis and other inflammatory polyarthropathies Both 547 5040 14 musculoskeletal darkolivegreen 5040, 547 1260, 146 1260, 128 1260, 138 1260, 134 -0.0451 0.0463 0.33 0.4811 0.956 0.873 1.05 -0.125 0.127 0.325 0.4878 0.882 0.688 1.13 -0.0597 0.127 0.637 0.1957 0.942 0.735 1.21 -0.118 0.131 0.365 0.4383 0.888 0.688 1.15 PRS_PLINK_0.0199526231496888 FALSE 714.1 Rheumatoid arthritis Both 432 4028 14 musculoskeletal darkolivegreen 4028, 432 1007, 119 1007, 98 1007, 110 1007, 104 -0.0542 0.052 0.298 0.5262 0.947 0.855 1.05 -0.188 0.143 0.19 0.7215 0.829 0.626 1.1 -0.0778 0.141 0.58 0.2367 0.925 0.702 1.22 -0.178 0.146 0.224 0.6501 0.837 0.628 1.11 PRS_PLINK_0.0199526231496888 FALSE 714.2 Juvenile rheumatoid arthritis Both 37 298 14 musculoskeletal darkolivegreen 298, 37 75, 8 74, 13 74, 9 75, 7 0.0167 0.187 0.929 0.03207 1.02 0.705 1.47 0.501 0.476 0.293 0.5327 1.65 0.649 4.2 0.126 0.515 0.807 0.09332 1.13 0.414 3.11 -0.0708 0.53 0.894 0.04873 0.932 0.329 2.64 PRS_PLINK_0.0199526231496888 TRUE 715 Other inflammatory spondylopathies Both 267 2902 14 musculoskeletal darkolivegreen 2902, 267 726, 72 725, 59 725, 64 726, 72 0.00482 0.0659 0.942 0.02608 1 0.883 1.14 -0.185 0.182 0.309 0.5101 0.831 0.582 1.19 -0.142 0.18 0.431 0.3658 0.868 0.609 1.24 -0.0508 0.178 0.775 0.1108 0.95 0.671 1.35 PRS_PLINK_0.0199526231496888 FALSE 715.1 Sacroiliitis NEC Both 64 758 14 musculoskeletal darkolivegreen 758, 64 190, 17 189, 15 189, 12 190, 20 -0.0104 0.133 0.937 0.02804 0.99 0.763 1.28 -0.14 0.353 0.691 0.1608 0.869 0.435 1.73 -0.296 0.385 0.442 0.3548 0.743 0.349 1.58 0.0718 0.342 0.834 0.07906 1.07 0.55 2.1 PRS_PLINK_0.0199526231496888 FALSE 715.2 Ankylosing spondylitis Both 51 609 14 musculoskeletal darkolivegreen 609, 51 153, 14 152, 14 152, 12 152, 11 -0.0318 0.149 0.831 0.08055 0.969 0.724 1.3 -0.0218 0.378 0.954 0.02043 0.978 0.467 2.05 -0.201 0.395 0.61 0.2146 0.818 0.377 1.77 -0.279 0.402 0.487 0.3124 0.756 0.344 1.66 PRS_PLINK_0.0199526231496888 FALSE 716 Other arthropathies Both 3087 9165 14 musculoskeletal darkolivegreen 9165, 3087 2292, 841 2291, 728 2291, 790 2291, 727 -0.014 0.0222 0.527 0.2786 0.986 0.944 1.03 -0.115 0.0615 0.0616 1.211 0.891 0.79 1.01 -0.0226 0.0612 0.712 0.1477 0.978 0.867 1.1 -0.106 0.0641 0.0984 1.007 0.9 0.793 1.02 PRS_PLINK_0.0199526231496888 FALSE 716.1 Unspecified polyarthropathy or polyarthritis Both 52 530 14 musculoskeletal darkolivegreen 530, 52 133, 18 132, 9 132, 12 133, 13 -0.105 0.152 0.493 0.3072 0.901 0.668 1.21 -0.65 0.407 0.11 0.957 0.522 0.235 1.16 -0.479 0.387 0.216 0.6649 0.619 0.29 1.32 -0.365 0.394 0.354 0.4506 0.694 0.32 1.5 PRS_PLINK_0.0199526231496888 FALSE 716.2 Unspecified monoarthritis Both 38 311 14 musculoskeletal darkolivegreen 311, 38 78, 7 78, 11 77, 9 78, 11 0.0655 0.162 0.685 0.1642 1.07 0.778 1.47 0.288 0.486 0.554 0.2566 1.33 0.515 3.45 0.192 0.49 0.696 0.1577 1.21 0.464 3.16 0.45 0.497 0.365 0.4377 1.57 0.592 4.15 PRS_PLINK_0.0199526231496888 TRUE 716.9 Arthropathy NOS Both 3068 9161 14 musculoskeletal darkolivegreen 9161, 3068 2291, 836 2290, 725 2290, 785 2290, 721 -0.0144 0.0222 0.517 0.2867 0.986 0.944 1.03 -0.112 0.0617 0.0688 1.162 0.894 0.792 1.01 -0.0229 0.0613 0.709 0.1492 0.977 0.867 1.1 -0.108 0.0642 0.0931 1.031 0.898 0.792 1.02 PRS_PLINK_0.0199526231496888 FALSE 717 Polymyalgia Rheumatica Both 37 445 14 musculoskeletal darkolivegreen 445, 37 112, 9 111, 8 111, 10 111, 10 0.048 0.183 0.793 0.1008 1.05 0.733 1.5 -0.241 0.467 0.606 0.2178 0.786 0.315 1.96 0.188 0.467 0.688 0.1627 1.21 0.483 3.01 0.0509 0.503 0.919 0.0365 1.05 0.393 2.82 PRS_PLINK_0.0199526231496888 TRUE 720 Spinal stenosis Both 770 6812 14 musculoskeletal darkolivegreen 6812, 770 1703, 210 1703, 186 1703, 189 1703, 185 -0.0166 0.0394 0.674 0.1712 0.984 0.91 1.06 -0.118 0.107 0.273 0.5643 0.889 0.721 1.1 -0.0888 0.108 0.413 0.384 0.915 0.74 1.13 -0.0984 0.111 0.376 0.4246 0.906 0.729 1.13 PRS_PLINK_0.0199526231496888 FALSE 720.1 Spinal stenosis of lumbar region Both 554 5192 14 musculoskeletal darkolivegreen 5192, 554 1298, 153 1298, 132 1298, 130 1298, 139 -0.0156 0.0461 0.735 0.1339 0.984 0.899 1.08 -0.146 0.126 0.246 0.6086 0.865 0.676 1.11 -0.142 0.128 0.268 0.5727 0.868 0.676 1.11 -0.0665 0.129 0.606 0.2174 0.936 0.727 1.2 PRS_PLINK_0.0199526231496888 FALSE 721 Spondylosis and allied disorders Both 1214 8480 14 musculoskeletal darkolivegreen 8480, 1214 2120, 318 2120, 318 2120, 288 2120, 289 -0.0278 0.0318 0.381 0.4189 0.973 0.914 1.04 0.0209 0.0861 0.808 0.09234 1.02 0.863 1.21 -0.0719 0.0891 0.42 0.3769 0.931 0.782 1.11 -0.0637 0.0915 0.487 0.3128 0.938 0.784 1.12 PRS_PLINK_0.0199526231496888 FALSE 721.1 Spondylosis without myelopathy Both 1130 8273 14 musculoskeletal darkolivegreen 8273, 1130 2069, 300 2068, 290 2068, 271 2068, 268 -0.0293 0.0328 0.373 0.4288 0.971 0.911 1.04 -0.00843 0.0891 0.925 0.03403 0.992 0.833 1.18 -0.0739 0.0915 0.419 0.3775 0.929 0.776 1.11 -0.0834 0.0944 0.377 0.424 0.92 0.765 1.11 PRS_PLINK_0.0199526231496888 FALSE 721.2 Spondylosis with myelopathy Both 179 1899 14 musculoskeletal darkolivegreen 1899, 179 475, 36 475, 55 474, 43 475, 45 0.0473 0.0812 0.56 0.2517 1.05 0.894 1.23 0.43 0.222 0.0525 1.28 1.54 0.995 2.37 0.143 0.236 0.543 0.2652 1.15 0.727 1.83 0.286 0.24 0.232 0.6338 1.33 0.832 2.13 PRS_PLINK_0.0199526231496888 FALSE 721.8 Other allied disorders of spine Both 71 598 14 musculoskeletal darkolivegreen 598, 71 150, 19 149, 19 149, 16 150, 17 -0.122 0.127 0.339 0.4704 0.886 0.69 1.14 -0.128 0.343 0.71 0.149 0.88 0.449 1.72 -0.187 0.353 0.596 0.2248 0.829 0.416 1.66 -0.226 0.351 0.519 0.285 0.798 0.401 1.59 PRS_PLINK_0.0199526231496888 FALSE 722 Intervertebral disc disorders Both 1531 9336 14 musculoskeletal darkolivegreen 9336, 1531 2334, 379 2334, 387 2334, 399 2334, 366 0.0041 0.0286 0.886 0.05244 1 0.949 1.06 0.0201 0.0789 0.799 0.09747 1.02 0.874 1.19 0.0425 0.0794 0.593 0.2272 1.04 0.893 1.22 -0.00167 0.0831 0.984 0.007012 0.998 0.848 1.17 PRS_PLINK_0.0199526231496888 FALSE 722.1 Displacement of intervertebral disc Both 899 8314 14 musculoskeletal darkolivegreen 8314, 899 2079, 233 2078, 228 2078, 224 2079, 214 -0.0168 0.0364 0.643 0.1916 0.983 0.916 1.06 -0.0209 0.0985 0.832 0.07971 0.979 0.807 1.19 -0.0412 0.1 0.682 0.1665 0.96 0.788 1.17 -0.0678 0.104 0.515 0.2882 0.934 0.762 1.15 PRS_PLINK_0.0199526231496888 FALSE 722.3 Schmorl's nodes Both 33 276 14 musculoskeletal darkolivegreen 276, 33 69, 7 69, 10 69, 12 69, 4 -0.117 0.198 0.554 0.2568 0.889 0.603 1.31 0.233 0.506 0.645 0.1905 1.26 0.468 3.41 0.631 0.517 0.222 0.6542 1.88 0.683 5.18 -0.811 0.682 0.234 0.6312 0.444 0.117 1.69 PRS_PLINK_0.0199526231496888 TRUE 722.6 Degeneration of intervertebral disc Both 914 7775 14 musculoskeletal darkolivegreen 7775, 914 1944, 223 1944, 229 1943, 235 1944, 227 0.015 0.0362 0.678 0.1691 1.02 0.946 1.09 0.0256 0.0999 0.798 0.09808 1.03 0.843 1.25 0.0649 0.101 0.519 0.2848 1.07 0.876 1.3 0.0236 0.104 0.82 0.08609 1.02 0.836 1.25 PRS_PLINK_0.0199526231496888 FALSE 722.7 Intervertebral disc disorder with myelopathy Both 115 1155 14 musculoskeletal darkolivegreen 1155, 115 289, 30 289, 25 288, 29 289, 31 0.00343 0.102 0.973 0.01185 1 0.822 1.22 -0.173 0.279 0.534 0.2724 0.841 0.487 1.45 0.0385 0.274 0.888 0.0516 1.04 0.608 1.78 0.202 0.275 0.463 0.3347 1.22 0.713 2.1 PRS_PLINK_0.0199526231496888 FALSE 722.8 Postlaminectomy syndrome Both 97 942 14 musculoskeletal darkolivegreen 942, 97 236, 21 235, 28 235, 27 236, 21 -0.0156 0.115 0.892 0.04963 0.985 0.786 1.23 0.247 0.298 0.407 0.3907 1.28 0.714 2.3 0.332 0.307 0.279 0.5538 1.39 0.764 2.54 0.0405 0.325 0.901 0.04544 1.04 0.551 1.97 PRS_PLINK_0.0199526231496888 FALSE 722.9 Other and unspecified disc disorder Both 463 4907 14 musculoskeletal darkolivegreen 4907, 463 1227, 123 1227, 109 1226, 111 1227, 120 -0.0194 0.05 0.698 0.156 0.981 0.889 1.08 -0.141 0.137 0.306 0.5148 0.869 0.664 1.14 -0.0648 0.138 0.639 0.1943 0.937 0.715 1.23 -0.0392 0.139 0.777 0.1093 0.962 0.733 1.26 PRS_PLINK_0.0199526231496888 FALSE 723 Other disorders of cervical region Both 260 2499 14 musculoskeletal darkolivegreen 2499, 260 625, 76 625, 55 624, 64 625, 65 -0.0607 0.0673 0.368 0.4345 0.941 0.825 1.07 -0.33 0.184 0.0733 1.135 0.719 0.501 1.03 -0.167 0.18 0.355 0.4495 0.846 0.594 1.21 -0.152 0.183 0.408 0.3897 0.859 0.6 1.23 PRS_PLINK_0.0199526231496888 FALSE 723.1 Torticollis Both 71 635 14 musculoskeletal darkolivegreen 635, 71 159, 22 159, 14 158, 20 159, 15 -0.0898 0.128 0.481 0.3175 0.914 0.712 1.17 -0.411 0.347 0.236 0.6275 0.663 0.336 1.31 -0.0362 0.33 0.913 0.03971 0.964 0.506 1.84 -0.49 0.363 0.177 0.7523 0.613 0.301 1.25 PRS_PLINK_0.0199526231496888 FALSE 724 Other and unspecified disorders of back Both 1190 8948 14 musculoskeletal darkolivegreen 8948, 1190 2237, 304 2237, 318 2237, 287 2237, 280 -0.026 0.0319 0.416 0.381 0.974 0.915 1.04 0.0469 0.0861 0.586 0.2319 1.05 0.885 1.24 -0.0303 0.0893 0.734 0.1342 0.97 0.814 1.16 -0.0388 0.0923 0.675 0.171 0.962 0.803 1.15 PRS_PLINK_0.0199526231496888 FALSE 724.1 Disorders of sacrum Both 663 6181 14 musculoskeletal darkolivegreen 6181, 663 1546, 175 1545, 162 1545, 158 1545, 167 -0.0401 0.0423 0.343 0.4648 0.961 0.884 1.04 -0.0895 0.115 0.436 0.3601 0.914 0.73 1.15 -0.0897 0.117 0.444 0.3526 0.914 0.727 1.15 -0.0685 0.119 0.565 0.2476 0.934 0.739 1.18 PRS_PLINK_0.0199526231496888 FALSE 724.2 Disorders of coccyx Both 143 1260 14 musculoskeletal darkolivegreen 1260, 143 315, 34 315, 38 315, 29 315, 42 0.0599 0.0912 0.511 0.2913 1.06 0.888 1.27 0.159 0.248 0.522 0.2827 1.17 0.721 1.91 -0.148 0.266 0.579 0.2372 0.863 0.512 1.45 0.237 0.252 0.346 0.4607 1.27 0.774 2.08 PRS_PLINK_0.0199526231496888 FALSE 724.8 Other symptoms referable to back Both 274 2524 14 musculoskeletal darkolivegreen 2524, 274 631, 69 631, 81 631, 71 631, 53 -0.0677 0.0653 0.3 0.5229 0.935 0.822 1.06 0.155 0.172 0.367 0.4349 1.17 0.833 1.64 0.0589 0.181 0.744 0.1282 1.06 0.744 1.51 -0.207 0.198 0.298 0.526 0.813 0.551 1.2 PRS_PLINK_0.0199526231496888 FALSE 724.9 Other unspecified back disorders Both 403 3433 14 musculoskeletal darkolivegreen 3433, 403 859, 101 858, 112 858, 96 858, 94 -0.0159 0.0552 0.774 0.1112 0.984 0.883 1.1 0.121 0.146 0.405 0.3923 1.13 0.849 1.5 -0.0229 0.152 0.88 0.05532 0.977 0.726 1.32 -0.0319 0.157 0.839 0.07625 0.969 0.712 1.32 PRS_PLINK_0.0199526231496888 FALSE 726 Peripheral enthesopathies and allied syndromes Both 2572 8342 14 musculoskeletal darkolivegreen 8342, 2572 2086, 697 2085, 675 2085, 600 2086, 599 -0.0506 0.0235 0.0312 1.506 0.951 0.908 0.995 -0.00588 0.0634 0.926 0.03334 0.994 0.878 1.13 -0.132 0.0657 0.0441 1.355 0.876 0.77 0.997 -0.0858 0.0678 0.206 0.6858 0.918 0.804 1.05 PRS_PLINK_0.0199526231496888 FALSE 726.1 Enthesopathy Both 1958 8313 14 musculoskeletal darkolivegreen 8313, 1958 2079, 539 2078, 514 2078, 454 2078, 450 -0.0583 0.0261 0.0256 1.592 0.943 0.896 0.993 -0.0235 0.0702 0.738 0.1322 0.977 0.851 1.12 -0.163 0.0731 0.0257 1.591 0.85 0.736 0.98 -0.118 0.0753 0.116 0.935 0.888 0.766 1.03 PRS_PLINK_0.0199526231496888 FALSE 726.2 Synoviopathy Both 210 2346 14 musculoskeletal darkolivegreen 2346, 210 587, 56 586, 58 586, 51 587, 44 -0.0998 0.0736 0.175 0.7573 0.905 0.783 1.05 0.0106 0.196 0.957 0.01908 1.01 0.688 1.48 -0.0859 0.203 0.673 0.1723 0.918 0.616 1.37 -0.282 0.218 0.195 0.7092 0.754 0.492 1.16 PRS_PLINK_0.0199526231496888 FALSE 726.3 Bursitis Both 442 4255 14 musculoskeletal darkolivegreen 4255, 442 1064, 120 1064, 113 1063, 96 1064, 113 -0.0203 0.0518 0.695 0.1578 0.98 0.885 1.08 -0.0572 0.139 0.68 0.1676 0.944 0.72 1.24 -0.209 0.146 0.153 0.816 0.812 0.61 1.08 -0.0629 0.145 0.664 0.1779 0.939 0.707 1.25 PRS_PLINK_0.0199526231496888 FALSE 726.4 Calcaneal spur; Exostosis NOS Both 312 2991 14 musculoskeletal darkolivegreen 2991, 312 748, 96 748, 77 747, 73 748, 66 -0.138 0.0611 0.0239 1.622 0.871 0.773 0.982 -0.271 0.162 0.0941 1.026 0.762 0.555 1.05 -0.338 0.166 0.0419 1.378 0.714 0.515 0.988 -0.406 0.174 0.0196 1.707 0.667 0.474 0.937 PRS_PLINK_0.0199526231496888 FALSE 727 Other disorders of synovium, tendon, and bursa Both 1845 8321 14 musculoskeletal darkolivegreen 8321, 1845 2081, 527 2080, 472 2080, 443 2080, 403 -0.0758 0.0268 0.00472 2.326 0.927 0.879 0.977 -0.0891 0.0717 0.214 0.6697 0.915 0.795 1.05 -0.165 0.0737 0.0255 1.594 0.848 0.734 0.98 -0.23 0.0776 0.003 2.522 0.794 0.682 0.925 PRS_PLINK_0.0199526231496888 FALSE 727.1 Synovitis and tenosynovitis Both 764 7045 14 musculoskeletal darkolivegreen 7045, 764 1762, 216 1761, 214 1761, 175 1761, 159 -0.114 0.0396 0.0039 2.409 0.892 0.825 0.964 0.00143 0.103 0.989 0.004858 1 0.819 1.23 -0.186 0.109 0.0894 1.048 0.831 0.671 1.03 -0.305 0.116 0.00842 2.075 0.737 0.587 0.925 PRS_PLINK_0.0199526231496888 FALSE 727.2 Bursitis disorders Both 104 1008 14 musculoskeletal darkolivegreen 1008, 104 252, 25 252, 29 252, 27 252, 23 0.00922 0.106 0.93 0.03132 1.01 0.821 1.24 0.0609 0.287 0.832 0.0798 1.06 0.605 1.87 0.0607 0.291 0.835 0.07848 1.06 0.601 1.88 -0.129 0.309 0.677 0.1695 0.879 0.48 1.61 PRS_PLINK_0.0199526231496888 FALSE 727.4 Ganglion and cyst of synovium, tendon, and bursa Both 371 3702 14 musculoskeletal darkolivegreen 3702, 371 926, 112 925, 82 925, 97 926, 80 -0.0723 0.0563 0.199 0.701 0.93 0.833 1.04 -0.309 0.152 0.0423 1.373 0.734 0.545 0.989 -0.131 0.148 0.374 0.4269 0.877 0.656 1.17 -0.304 0.161 0.0593 1.227 0.738 0.539 1.01 PRS_PLINK_0.0199526231496888 FALSE 727.5 Rupture of synovium Both 97 1135 14 musculoskeletal darkolivegreen 1135, 97 284, 31 284, 25 283, 24 284, 17 -0.197 0.11 0.0742 1.129 0.821 0.661 1.02 -0.242 0.28 0.388 0.4115 0.785 0.453 1.36 -0.284 0.281 0.312 0.506 0.752 0.434 1.31 -0.608 0.321 0.0584 1.234 0.544 0.29 1.02 PRS_PLINK_0.0199526231496888 FALSE 727.6 Rupture of tendon, nontraumatic Both 470 4928 14 musculoskeletal darkolivegreen 4928, 470 1232, 131 1232, 117 1232, 109 1232, 113 -0.0755 0.0496 0.127 0.8945 0.927 0.841 1.02 -0.097 0.134 0.468 0.3293 0.908 0.698 1.18 -0.2 0.138 0.148 0.8283 0.819 0.625 1.07 -0.153 0.14 0.277 0.5573 0.858 0.652 1.13 PRS_PLINK_0.0199526231496888 FALSE 727.7 Contracture of tendon (sheath) Both 192 1803 14 musculoskeletal darkolivegreen 1803, 192 451, 56 451, 42 450, 53 451, 41 -0.0361 0.0776 0.642 0.1925 0.965 0.828 1.12 -0.285 0.212 0.178 0.7502 0.752 0.497 1.14 -0.05 0.204 0.807 0.09332 0.951 0.637 1.42 -0.378 0.224 0.0916 1.038 0.685 0.442 1.06 PRS_PLINK_0.0199526231496888 FALSE 727.8 Plica syndrome Both 52 443 14 musculoskeletal darkolivegreen 443, 52 111, 18 111, 13 110, 11 111, 10 -0.256 0.152 0.0927 1.033 0.774 0.574 1.04 -0.303 0.384 0.431 0.3659 0.739 0.348 1.57 -0.465 0.412 0.26 0.5853 0.628 0.28 1.41 -0.492 0.44 0.264 0.5787 0.612 0.258 1.45 PRS_PLINK_0.0199526231496888 FALSE 728 Disorders of muscle, ligament, and fascia Both 1213 8090 14 musculoskeletal darkolivegreen 8090, 1213 2023, 323 2022, 288 2022, 315 2023, 287 -0.0138 0.0319 0.665 0.1772 0.986 0.927 1.05 -0.0866 0.0878 0.324 0.4893 0.917 0.772 1.09 -0.017 0.0873 0.845 0.07299 0.983 0.828 1.17 -0.0636 0.092 0.49 0.3102 0.938 0.784 1.12 PRS_PLINK_0.0199526231496888 FALSE 728.1 Muscular calcification and ossification Both 28 197 14 musculoskeletal darkolivegreen 197, 28 50, 11 49, 9 49, 5 49, 3 -0.433 0.223 0.0522 1.283 0.649 0.419 1 -0.515 0.515 0.318 0.498 0.598 0.218 1.64 -0.751 0.56 0.179 0.746 0.472 0.157 1.41 -1.54 0.707 0.029 1.538 0.213 0.0534 0.853 PRS_PLINK_0.0199526231496888 TRUE 728.2 Laxity of ligament or hypermobility syndrome Both 90 811 14 musculoskeletal darkolivegreen 811, 90 203, 23 203, 29 202, 16 203, 22 -0.125 0.109 0.253 0.5973 0.883 0.713 1.09 0.214 0.295 0.468 0.3293 1.24 0.695 2.21 -0.359 0.347 0.301 0.5211 0.698 0.354 1.38 0.0844 0.327 0.796 0.09887 1.09 0.573 2.07 PRS_PLINK_0.0199526231496888 FALSE 728.7 Fasciitis Both 650 6215 14 musculoskeletal darkolivegreen 6215, 650 1554, 173 1554, 162 1553, 171 1554, 143 -0.0639 0.043 0.137 0.8633 0.938 0.862 1.02 -0.0493 0.116 0.671 0.1736 0.952 0.758 1.19 -0.0193 0.116 0.868 0.06147 0.981 0.781 1.23 -0.193 0.125 0.121 0.9155 0.824 0.646 1.05 PRS_PLINK_0.0199526231496888 FALSE 728.71 Contracture of palmar fascia [Dupuytren's disease] Both 79 806 14 musculoskeletal darkolivegreen 806, 79 202, 23 201, 20 201, 23 202, 13 -0.156 0.122 0.201 0.6966 0.856 0.674 1.09 -0.112 0.311 0.719 0.1433 0.894 0.486 1.64 -0.049 0.307 0.873 0.05883 0.952 0.521 1.74 -0.457 0.356 0.199 0.7017 0.633 0.315 1.27 PRS_PLINK_0.0199526231496888 FALSE 729 Other disorders of soft tissues Both 923 7263 14 musculoskeletal darkolivegreen 7263, 923 1816, 228 1816, 237 1815, 228 1816, 229 0.0242 0.0362 0.503 0.2987 1.02 0.954 1.1 0.0706 0.0993 0.477 0.3214 1.07 0.883 1.3 0.012 0.102 0.907 0.04257 1.01 0.829 1.24 0.0401 0.105 0.703 0.1533 1.04 0.847 1.28 PRS_PLINK_0.0199526231496888 FALSE 729.1 Rheumatism, unspecified and fibrositis Both 24 201 14 musculoskeletal darkolivegreen 201, 24 51, 2 50, 9 50, 6 50, 7 0.199 0.203 0.327 0.4858 1.22 0.819 1.82 1.23 0.692 0.0746 1.127 3.43 0.885 13.3 1.15 0.741 0.119 0.9233 3.17 0.742 13.5 0.797 0.691 0.248 0.6051 2.22 0.573 8.59 PRS_PLINK_0.0199526231496888 TRUE 729.3 Panniculitis Both 37 327 14 musculoskeletal darkolivegreen 327, 37 82, 6 82, 8 81, 9 82, 14 0.252 0.179 0.159 0.7973 1.29 0.906 1.83 0.357 0.539 0.508 0.2942 1.43 0.496 4.11 0.304 0.549 0.579 0.237 1.36 0.462 3.98 0.762 0.55 0.165 0.7815 2.14 0.73 6.29 PRS_PLINK_0.0199526231496888 TRUE 729.7 Nontraumatic compartment syndrome Both 24 167 14 musculoskeletal darkolivegreen 167, 24 42, 6 42, 4 41, 6 42, 8 0.21 0.236 0.373 0.4284 1.23 0.777 1.96 -0.17 0.652 0.795 0.09976 0.844 0.235 3.03 -0.308 0.652 0.637 0.1961 0.735 0.205 2.64 0.0774 0.566 0.891 0.05003 1.08 0.356 3.28 PRS_PLINK_0.0199526231496888 TRUE 731 Osteitis deformans and osteopathies associated with other disorders classified elsewhere Both 36 418 14 musculoskeletal darkolivegreen 418, 36 105, 7 104, 11 104, 9 105, 9 0.136 0.169 0.422 0.3751 1.15 0.823 1.59 0.48 0.477 0.314 0.5032 1.62 0.635 4.12 0.47 0.546 0.389 0.4097 1.6 0.548 4.67 0.356 0.526 0.498 0.3029 1.43 0.51 4 PRS_PLINK_0.0199526231496888 TRUE 732 Osteochondropathies Both 120 1214 14 musculoskeletal darkolivegreen 1214, 120 304, 26 303, 35 303, 30 304, 29 0.00716 0.0995 0.943 0.02568 1.01 0.829 1.22 0.252 0.266 0.343 0.4644 1.29 0.764 2.17 0.132 0.281 0.639 0.1943 1.14 0.658 1.98 -0.0512 0.292 0.861 0.0651 0.95 0.536 1.68 PRS_PLINK_0.0199526231496888 FALSE 732.1 Juvenile osteochondrosis Both 60 599 14 musculoskeletal darkolivegreen 599, 60 150, 16 150, 21 149, 13 150, 10 -0.16 0.14 0.255 0.5931 0.853 0.648 1.12 0.223 0.352 0.525 0.2795 1.25 0.627 2.49 -0.125 0.389 0.747 0.1265 0.882 0.412 1.89 -0.752 0.439 0.0868 1.062 0.471 0.199 1.11 PRS_PLINK_0.0199526231496888 FALSE 732.7 Osteochondritis dissecans Both 30 284 14 musculoskeletal darkolivegreen 284, 30 71, 7 71, 8 71, 6 71, 9 0.255 0.205 0.214 0.6701 1.29 0.863 1.93 -0.147 0.561 0.793 0.1006 0.863 0.288 2.59 0.00217 0.543 0.997 0.001386 1 0.346 2.9 0.285 0.544 0.601 0.2211 1.33 0.458 3.86 PRS_PLINK_0.0199526231496888 TRUE 733 Other disorders of bone and cartilage Both 1168 7307 14 musculoskeletal darkolivegreen 7307, 1168 1827, 344 1827, 279 1826, 263 1827, 282 -0.0318 0.0327 0.33 0.4815 0.969 0.909 1.03 -0.189 0.0886 0.0329 1.483 0.828 0.696 0.985 -0.244 0.0911 0.00739 2.131 0.784 0.655 0.937 -0.134 0.0918 0.144 0.8427 0.874 0.73 1.05 PRS_PLINK_0.0199526231496888 FALSE 733.2 Cyst of bone Both 57 555 14 musculoskeletal darkolivegreen 555, 57 139, 26 139, 10 138, 10 139, 11 -0.298 0.14 0.033 1.481 0.742 0.564 0.976 -0.876 0.374 0.0191 1.719 0.417 0.2 0.866 -0.865 0.377 0.0217 1.665 0.421 0.201 0.881 -0.825 0.373 0.0269 1.57 0.438 0.211 0.91 PRS_PLINK_0.0199526231496888 FALSE 733.4 Aseptic necrosis of bone Both 151 1182 14 musculoskeletal darkolivegreen 1182, 151 296, 41 295, 30 295, 45 296, 35 0.00607 0.0891 0.946 0.02424 1.01 0.845 1.2 -0.315 0.25 0.208 0.6823 0.73 0.447 1.19 0.0814 0.23 0.723 0.1408 1.08 0.691 1.7 -0.296 0.254 0.245 0.6101 0.744 0.452 1.23 PRS_PLINK_0.0199526231496888 FALSE 733.6 Costochondritis Both 140 1187 14 musculoskeletal darkolivegreen 1187, 140 297, 43 297, 34 296, 29 297, 34 -0.106 0.0964 0.27 0.5681 0.899 0.744 1.09 -0.22 0.243 0.366 0.4363 0.803 0.498 1.29 -0.447 0.258 0.0835 1.078 0.639 0.385 1.06 -0.399 0.259 0.124 0.9068 0.671 0.404 1.12 PRS_PLINK_0.0199526231496888 FALSE 733.8 Malunion and nonunion of fracture Both 242 2135 14 musculoskeletal darkolivegreen 2135, 242 534, 61 534, 57 533, 59 534, 65 0.0615 0.0693 0.375 0.4264 1.06 0.928 1.22 -0.0447 0.193 0.817 0.08783 0.956 0.655 1.4 -0.0846 0.196 0.666 0.1768 0.919 0.626 1.35 0.121 0.196 0.537 0.2704 1.13 0.769 1.66 PRS_PLINK_0.0199526231496888 FALSE 733.9 Chondromalacia Both 43 318 14 musculoskeletal darkolivegreen 318, 43 80, 10 79, 8 79, 11 80, 14 0.155 0.17 0.362 0.441 1.17 0.836 1.63 -0.0173 0.503 0.972 0.01212 0.983 0.367 2.63 0.332 0.47 0.48 0.319 1.39 0.555 3.5 0.44 0.472 0.352 0.454 1.55 0.615 3.92 PRS_PLINK_0.0199526231496888 TRUE 735 Acquired foot deformities Both 844 7687 14 musculoskeletal darkolivegreen 7687, 844 1922, 219 1922, 209 1921, 184 1922, 231 -0.00642 0.0374 0.864 0.06369 0.994 0.923 1.07 -0.0305 0.102 0.766 0.116 0.97 0.794 1.19 -0.194 0.107 0.0698 1.156 0.823 0.667 1.02 0.0752 0.105 0.472 0.3257 1.08 0.878 1.32 PRS_PLINK_0.0199526231496888 FALSE 735.1 Flat foot Both 144 1567 14 musculoskeletal darkolivegreen 1567, 144 392, 35 392, 41 391, 30 392, 38 -0.0165 0.0884 0.852 0.06973 0.984 0.827 1.17 0.15 0.239 0.53 0.2759 1.16 0.728 1.85 -0.22 0.258 0.393 0.4057 0.802 0.484 1.33 0.0653 0.251 0.794 0.09996 1.07 0.653 1.74 PRS_PLINK_0.0199526231496888 FALSE 735.2 Acquired toe deformities Both 271 2689 14 musculoskeletal darkolivegreen 2689, 271 673, 67 672, 77 672, 60 672, 67 0.00093 0.0644 0.988 0.005035 1 0.882 1.14 0.161 0.176 0.358 0.4462 1.18 0.833 1.66 -0.062 0.189 0.742 0.1294 0.94 0.649 1.36 0.0758 0.19 0.69 0.1612 1.08 0.743 1.57 PRS_PLINK_0.0199526231496888 FALSE 735.21 Hammer toe (acquired) Both 160 1581 14 musculoskeletal darkolivegreen 1581, 160 396, 38 395, 43 395, 37 395, 42 -0.00447 0.0858 0.958 0.01841 0.996 0.841 1.18 0.161 0.231 0.487 0.3129 1.17 0.747 1.85 0.0187 0.244 0.939 0.02743 1.02 0.632 1.64 0.148 0.245 0.547 0.2623 1.16 0.717 1.88 PRS_PLINK_0.0199526231496888 FALSE 735.23 Hallux rigidus Both 87 929 14 musculoskeletal darkolivegreen 929, 87 233, 26 232, 24 232, 18 232, 19 -0.0494 0.114 0.665 0.1772 0.952 0.761 1.19 -0.0221 0.296 0.94 0.02665 0.978 0.548 1.75 -0.414 0.323 0.199 0.7004 0.661 0.351 1.24 -0.225 0.331 0.496 0.3043 0.798 0.417 1.53 PRS_PLINK_0.0199526231496888 FALSE 735.3 Hallux valgus (Bunion) Both 397 3780 14 musculoskeletal darkolivegreen 3780, 397 945, 108 945, 103 945, 78 945, 108 -0.0337 0.0548 0.539 0.2686 0.967 0.868 1.08 -0.0566 0.145 0.696 0.1574 0.945 0.711 1.26 -0.338 0.158 0.0321 1.493 0.713 0.523 0.971 -9.45e-05 0.15 0.999 0.0002183 1 0.745 1.34 PRS_PLINK_0.0199526231496888 FALSE 736 Other acquired deformities of limbs Both 740 6797 14 musculoskeletal darkolivegreen 6797, 740 1700, 182 1699, 198 1699, 160 1699, 199 -0.00484 0.0399 0.903 0.04418 0.995 0.92 1.08 0.0876 0.109 0.42 0.3768 1.09 0.882 1.35 -0.142 0.116 0.219 0.6587 0.868 0.692 1.09 0.111 0.114 0.331 0.4805 1.12 0.893 1.4 PRS_PLINK_0.0199526231496888 FALSE 736.1 Acquired deformities of forearm Both 34 240 14 musculoskeletal darkolivegreen 240, 34 60, 8 60, 6 60, 10 60, 10 -0.0386 0.19 0.839 0.07608 0.962 0.662 1.4 -0.0999 0.543 0.854 0.06856 0.905 0.312 2.62 0.0801 0.505 0.874 0.05845 1.08 0.402 2.92 0.0889 0.571 0.876 0.05742 1.09 0.357 3.34 PRS_PLINK_0.0199526231496888 TRUE 736.2 Acquired deformities of finger Both 56 575 14 musculoskeletal darkolivegreen 575, 56 144, 16 144, 16 143, 10 144, 14 0.006 0.145 0.967 0.0146 1.01 0.758 1.34 -0.0282 0.362 0.938 0.0279 0.972 0.479 1.97 -0.406 0.406 0.318 0.4972 0.667 0.3 1.48 -0.293 0.402 0.466 0.3317 0.746 0.339 1.64 PRS_PLINK_0.0199526231496888 FALSE 736.3 Acquired deformities of hip Both 33 250 14 musculoskeletal darkolivegreen 250, 33 63, 7 62, 5 62, 9 63, 12 0.253 0.19 0.183 0.7365 1.29 0.887 1.87 -0.308 0.577 0.593 0.2267 0.735 0.237 2.28 0.37 0.519 0.475 0.323 1.45 0.524 4 0.388 0.533 0.467 0.3306 1.47 0.518 4.19 PRS_PLINK_0.0199526231496888 TRUE 736.4 Genu valgum or varum (acquired) Both 65 726 14 musculoskeletal darkolivegreen 726, 65 182, 24 181, 18 181, 11 182, 12 -0.304 0.128 0.0178 1.748 0.738 0.574 0.949 -0.335 0.328 0.308 0.5121 0.716 0.376 1.36 -0.812 0.37 0.0283 1.548 0.444 0.215 0.917 -0.81 0.376 0.0315 1.502 0.445 0.213 0.931 PRS_PLINK_0.0199526231496888 FALSE 736.5 Acquired deformities of knee Both 56 563 14 musculoskeletal darkolivegreen 563, 56 141, 15 141, 14 140, 13 141, 14 -0.0942 0.138 0.495 0.305 0.91 0.694 1.19 -0.19 0.386 0.622 0.2062 0.827 0.388 1.76 -0.187 0.393 0.634 0.1982 0.829 0.384 1.79 -0.221 0.397 0.577 0.2386 0.802 0.368 1.74 PRS_PLINK_0.0199526231496888 FALSE 736.6 Unequal leg length (acquired) Both 103 937 14 musculoskeletal darkolivegreen 937, 103 235, 34 234, 24 234, 23 234, 22 -0.129 0.107 0.227 0.6438 0.879 0.713 1.08 -0.278 0.279 0.319 0.4961 0.758 0.439 1.31 -0.343 0.284 0.228 0.6414 0.71 0.407 1.24 -0.311 0.298 0.296 0.5293 0.732 0.409 1.31 PRS_PLINK_0.0199526231496888 FALSE 737 Curvature of spine Both 494 4199 14 musculoskeletal darkolivegreen 4199, 494 1050, 133 1050, 135 1049, 111 1050, 115 -0.0745 0.0498 0.134 0.8717 0.928 0.842 1.02 0.00307 0.13 0.981 0.008288 1 0.778 1.29 -0.187 0.138 0.175 0.7572 0.83 0.634 1.09 -0.144 0.14 0.304 0.5175 0.866 0.658 1.14 PRS_PLINK_0.0199526231496888 FALSE 737.1 Kyphosis (acquired) Both 133 1129 14 musculoskeletal darkolivegreen 1129, 133 283, 34 282, 36 282, 33 282, 30 -0.0446 0.0946 0.637 0.1958 0.956 0.795 1.15 0.00526 0.252 0.983 0.0073 1.01 0.614 1.65 -0.0584 0.26 0.822 0.08511 0.943 0.567 1.57 -0.163 0.272 0.55 0.2598 0.85 0.499 1.45 PRS_PLINK_0.0199526231496888 FALSE 737.2 Lordosis (acquired) Both 20 157 14 musculoskeletal darkolivegreen 157, 20 40, 5 39, 1 39, 4 39, 10 0.345 0.226 0.127 0.8947 1.41 0.906 2.2 -1.03 0.815 0.206 0.6868 0.356 0.0721 1.76 -0.149 0.656 0.82 0.08608 0.862 0.238 3.12 0.764 0.625 0.221 0.6548 2.15 0.631 7.3 PRS_PLINK_0.0199526231496888 TRUE 737.3 Kyphoscoliosis and scoliosis Both 399 3290 14 musculoskeletal darkolivegreen 3290, 399 823, 112 822, 105 822, 93 823, 89 -0.097 0.0551 0.0782 1.107 0.908 0.815 1.01 -0.0813 0.144 0.574 0.2414 0.922 0.695 1.22 -0.185 0.151 0.22 0.6582 0.831 0.619 1.12 -0.219 0.156 0.162 0.791 0.804 0.592 1.09 PRS_PLINK_0.0199526231496888 FALSE 738 Other acquired musculoskeletal deformity Both 622 6129 14 musculoskeletal darkolivegreen 6129, 622 1533, 158 1532, 149 1532, 169 1532, 146 -0.0254 0.0434 0.559 0.2529 0.975 0.896 1.06 -0.0597 0.12 0.618 0.2089 0.942 0.745 1.19 0.0794 0.118 0.501 0.3005 1.08 0.859 1.36 -0.0753 0.125 0.548 0.261 0.927 0.725 1.19 PRS_PLINK_0.0199526231496888 FALSE 738.4 Acquired spondylolisthesis Both 233 2324 14 musculoskeletal darkolivegreen 2324, 233 581, 56 581, 60 581, 63 581, 54 -0.00898 0.0709 0.899 0.04616 0.991 0.863 1.14 0.0398 0.193 0.837 0.07753 1.04 0.713 1.52 0.0979 0.193 0.613 0.2128 1.1 0.755 1.61 -0.0896 0.206 0.664 0.178 0.914 0.61 1.37 PRS_PLINK_0.0199526231496888 FALSE 739 Contracture of joint Both 170 1610 14 musculoskeletal darkolivegreen 1610, 170 403, 41 402, 42 402, 42 403, 45 0.0444 0.0832 0.593 0.2268 1.05 0.888 1.23 0.011 0.227 0.961 0.01709 1.01 0.647 1.58 0.029 0.231 0.9 0.04562 1.03 0.654 1.62 0.0492 0.234 0.833 0.07914 1.05 0.664 1.66 PRS_PLINK_0.0199526231496888 FALSE 740 Osteoarthrosis Both 3686 9013 14 musculoskeletal darkolivegreen 9013, 3686 2254, 1003 2253, 889 2253, 935 2253, 858 -0.0183 0.0213 0.389 0.4096 0.982 0.942 1.02 -0.0889 0.0586 0.129 0.8884 0.915 0.816 1.03 -0.0235 0.0588 0.69 0.1614 0.977 0.87 1.1 -0.0845 0.0619 0.172 0.7646 0.919 0.814 1.04 PRS_PLINK_0.0199526231496888 FALSE 740.1 Osteoarthritis; localized Both 1518 7602 14 musculoskeletal darkolivegreen 7602, 1518 1901, 425 1900, 380 1900, 374 1901, 339 -0.0563 0.03 0.0602 1.22 0.945 0.891 1 -0.0923 0.081 0.254 0.5946 0.912 0.778 1.07 -0.109 0.082 0.185 0.7334 0.897 0.764 1.05 -0.176 0.0862 0.041 1.387 0.838 0.708 0.993 PRS_PLINK_0.0199526231496888 FALSE 740.11 Osteoarthrosis, localized, primary Both 1297 7015 14 musculoskeletal darkolivegreen 7015, 1297 1754, 363 1754, 327 1753, 324 1754, 283 -0.0625 0.0321 0.0516 1.288 0.939 0.882 1 -0.0885 0.0867 0.307 0.5129 0.915 0.772 1.08 -0.0965 0.0875 0.27 0.5685 0.908 0.765 1.08 -0.195 0.0926 0.0356 1.448 0.823 0.686 0.987 PRS_PLINK_0.0199526231496888 FALSE 740.12 Osteoarthrosis, localized, secondary Both 195 1712 14 musculoskeletal darkolivegreen 1712, 195 428, 70 428, 47 428, 45 428, 33 -0.203 0.079 0.0101 1.997 0.816 0.699 0.953 -0.37 0.199 0.0631 1.2 0.691 0.468 1.02 -0.371 0.204 0.0687 1.163 0.69 0.463 1.03 -0.703 0.228 0.00205 2.688 0.495 0.317 0.774 PRS_PLINK_0.0199526231496888 FALSE 740.2 Osteoarthrosis, generalized Both 287 2726 14 musculoskeletal darkolivegreen 2726, 287 682, 93 681, 74 681, 56 682, 64 -0.127 0.0657 0.054 1.267 0.881 0.775 1 -0.255 0.168 0.128 0.8929 0.775 0.558 1.08 -0.515 0.181 0.0045 2.346 0.598 0.419 0.853 -0.353 0.178 0.0474 1.324 0.703 0.496 0.996 PRS_PLINK_0.0199526231496888 FALSE 740.3 Osteoarthrosis involving more than one site, but not specified as generalized Both 79 749 14 musculoskeletal darkolivegreen 749, 79 188, 22 187, 20 187, 18 187, 19 0.00464 0.124 0.97 0.01315 1 0.788 1.28 -0.0379 0.325 0.907 0.04234 0.963 0.509 1.82 -0.188 0.335 0.575 0.2406 0.829 0.43 1.6 -0.132 0.335 0.694 0.1589 0.876 0.454 1.69 PRS_PLINK_0.0199526231496888 FALSE 740.9 Osteoarthrosis NOS Both 3501 8980 14 musculoskeletal darkolivegreen 8980, 3501 2245, 958 2245, 831 2245, 899 2245, 812 -0.0189 0.0217 0.383 0.4169 0.981 0.94 1.02 -0.114 0.0599 0.0568 1.246 0.892 0.793 1 -0.0171 0.0598 0.776 0.1104 0.983 0.874 1.11 -0.0836 0.0631 0.185 0.7323 0.92 0.813 1.04 PRS_PLINK_0.0199526231496888 FALSE 741 Symptoms and disorders of the joints Both 2241 9837 14 musculoskeletal darkolivegreen 9837, 2241 2460, 587 2459, 569 2459, 560 2459, 524 -0.0321 0.0241 0.184 0.7342 0.968 0.924 1.02 -0.00997 0.066 0.88 0.05557 0.99 0.87 1.13 -0.0433 0.067 0.518 0.2853 0.958 0.84 1.09 -0.106 0.0699 0.131 0.8839 0.9 0.785 1.03 PRS_PLINK_0.0199526231496888 FALSE 741.1 Ankylosis of joint Both 68 701 14 musculoskeletal darkolivegreen 701, 68 176, 14 175, 26 175, 18 175, 10 -0.164 0.129 0.204 0.6899 0.849 0.66 1.09 0.629 0.343 0.067 1.174 1.88 0.957 3.68 0.211 0.374 0.572 0.2427 1.24 0.594 2.57 -0.184 0.432 0.67 0.1741 0.832 0.357 1.94 PRS_PLINK_0.0199526231496888 FALSE 741.2 Stiffness of joint Both 357 3412 14 musculoskeletal darkolivegreen 3412, 357 853, 98 853, 104 853, 77 853, 78 -0.104 0.0581 0.0738 1.132 0.901 0.804 1.01 0.061 0.149 0.683 0.1655 1.06 0.793 1.42 -0.257 0.162 0.113 0.9456 0.773 0.563 1.06 -0.274 0.167 0.101 0.995 0.76 0.548 1.06 PRS_PLINK_0.0199526231496888 FALSE 741.3 Difficulty in walking Both 617 5100 14 musculoskeletal darkolivegreen 5100, 617 1275, 154 1275, 151 1275, 165 1275, 146 0.0279 0.0437 0.523 0.2811 1.03 0.944 1.12 0.00769 0.121 0.95 0.0225 1.01 0.794 1.28 0.0606 0.12 0.614 0.2118 1.06 0.84 1.34 -0.0315 0.127 0.803 0.09506 0.969 0.756 1.24 PRS_PLINK_0.0199526231496888 FALSE 741.4 Joint effusions Both 612 6415 14 musculoskeletal darkolivegreen 6415, 612 1604, 167 1604, 147 1603, 144 1604, 154 -0.0393 0.0436 0.367 0.4349 0.962 0.883 1.05 -0.142 0.119 0.232 0.6344 0.868 0.688 1.09 -0.155 0.121 0.2 0.6992 0.857 0.676 1.09 -0.139 0.122 0.253 0.5962 0.87 0.685 1.1 PRS_PLINK_0.0199526231496888 FALSE 741.5 Hemarthrosis Both 28 221 14 musculoskeletal darkolivegreen 221, 28 56, 5 55, 10 55, 8 55, 5 -0.000331 0.195 0.999 0.000588 1 0.682 1.47 0.891 0.58 0.125 0.9036 2.44 0.781 7.6 0.379 0.577 0.511 0.2913 1.46 0.472 4.52 0.0076 0.628 0.99 0.004218 1.01 0.294 3.45 PRS_PLINK_0.0199526231496888 TRUE 741.6 Villonodular synovitis Both 18 178 14 musculoskeletal darkolivegreen 178, 18 45, 3 44, 5 44, 5 45, 5 0.0591 0.226 0.794 0.1002 1.06 0.681 1.65 0.725 0.716 0.312 0.506 2.06 0.507 8.4 1.08 0.827 0.19 0.7202 2.95 0.584 15 0.0346 0.683 0.96 0.01792 1.04 0.271 3.95 PRS_PLINK_0.0199526231496888 TRUE 742 Derangement of joint, non-traumatic Both 1294 9432 14 musculoskeletal darkolivegreen 9432, 1294 2358, 310 2358, 339 2358, 323 2358, 321 -0.00569 0.0306 0.853 0.06921 0.994 0.936 1.06 0.0925 0.0842 0.272 0.5647 1.1 0.93 1.29 0.041 0.0865 0.636 0.1968 1.04 0.879 1.23 0.014 0.0889 0.875 0.05805 1.01 0.852 1.21 PRS_PLINK_0.0199526231496888 FALSE 742.1 Loose body in joint Both 42 417 14 musculoskeletal darkolivegreen 417, 42 105, 8 104, 13 104, 12 104, 9 0.0173 0.162 0.915 0.03871 1.02 0.741 1.4 0.506 0.455 0.266 0.5757 1.66 0.68 4.04 0.289 0.472 0.54 0.2673 1.34 0.529 3.37 0.0326 0.491 0.947 0.02363 1.03 0.394 2.71 PRS_PLINK_0.0199526231496888 TRUE 742.2 Pathological, developmental or recurrent dislocation Both 105 911 14 musculoskeletal darkolivegreen 911, 105 228, 24 228, 27 227, 28 228, 26 0.0205 0.106 0.847 0.07223 1.02 0.829 1.26 0.145 0.291 0.618 0.2089 1.16 0.654 2.04 0.103 0.296 0.727 0.1386 1.11 0.621 1.98 0.0727 0.305 0.812 0.0906 1.08 0.591 1.96 PRS_PLINK_0.0199526231496888 FALSE 742.8 Articular cartilage disorder Both 66 742 14 musculoskeletal darkolivegreen 742, 66 186, 18 185, 16 185, 20 186, 12 -0.0745 0.139 0.592 0.2274 0.928 0.706 1.22 -0.109 0.348 0.753 0.1231 0.896 0.453 1.77 0.181 0.341 0.595 0.2254 1.2 0.614 2.34 -0.378 0.376 0.315 0.5022 0.685 0.328 1.43 PRS_PLINK_0.0199526231496888 FALSE 742.9 Other derangement of joint Both 1213 9282 14 musculoskeletal darkolivegreen 9282, 1213 2321, 288 2320, 320 2320, 305 2321, 299 -0.0019 0.0316 0.952 0.02136 0.998 0.938 1.06 0.109 0.0868 0.21 0.6772 1.11 0.94 1.32 0.0541 0.0891 0.543 0.2648 1.06 0.886 1.26 0.0142 0.0918 0.877 0.05705 1.01 0.847 1.21 PRS_PLINK_0.0199526231496888 FALSE 743 Osteoporosis, osteopenia and pathological fracture Both 2365 10202 14 musculoskeletal darkolivegreen 10202, 2365 2551, 626 2550, 618 2550, 554 2551, 566 -0.00446 0.0242 0.854 0.06849 0.996 0.949 1.04 0.0339 0.0662 0.609 0.2153 1.03 0.909 1.18 -0.0663 0.0681 0.331 0.4807 0.936 0.819 1.07 0.0399 0.0697 0.567 0.2464 1.04 0.908 1.19 PRS_PLINK_0.0199526231496888 FALSE 743.1 Osteoporosis Both 907 4736 14 musculoskeletal darkolivegreen 4736, 907 1184, 247 1184, 237 1184, 206 1184, 216 -0.0488 0.0384 0.203 0.6924 0.952 0.883 1.03 0.00901 0.103 0.93 0.03129 1.01 0.824 1.24 -0.13 0.108 0.227 0.6443 0.878 0.711 1.08 0.011 0.109 0.919 0.03658 1.01 0.817 1.25 PRS_PLINK_0.0199526231496888 FALSE 743.11 Osteoporosis NOS Both 902 4696 14 musculoskeletal darkolivegreen 4696, 902 1174, 247 1174, 234 1174, 205 1174, 215 -0.0471 0.0384 0.221 0.6565 0.954 0.885 1.03 -0.00668 0.103 0.949 0.02295 0.993 0.811 1.22 -0.134 0.108 0.214 0.6691 0.875 0.708 1.08 0.00726 0.109 0.947 0.02378 1.01 0.814 1.25 PRS_PLINK_0.0199526231496888 FALSE 743.12 Senile osteoporosis Both 158 1078 14 musculoskeletal darkolivegreen 1078, 158 270, 42 269, 38 269, 40 270, 38 -0.00349 0.0871 0.968 0.01412 0.997 0.84 1.18 -0.108 0.24 0.652 0.1855 0.897 0.56 1.44 0.0341 0.241 0.888 0.05183 1.03 0.645 1.66 0.00314 0.25 0.99 0.004375 1 0.615 1.64 PRS_PLINK_0.0199526231496888 FALSE 743.13 Other specified osteoporosis Both 84 637 14 musculoskeletal darkolivegreen 637, 84 160, 21 159, 21 159, 19 159, 23 0.00675 0.12 0.955 0.01986 1.01 0.795 1.27 0.00737 0.322 0.982 0.008017 1.01 0.536 1.89 -0.0519 0.33 0.875 0.05797 0.949 0.497 1.81 0.162 0.327 0.621 0.2071 1.18 0.62 2.23 PRS_PLINK_0.0199526231496888 FALSE 743.2 Pathologic fracture Both 298 2230 14 musculoskeletal darkolivegreen 2230, 298 558, 74 557, 73 557, 82 558, 69 -0.0379 0.0622 0.542 0.2663 0.963 0.852 1.09 -0.0264 0.174 0.88 0.05562 0.974 0.692 1.37 0.0836 0.171 0.626 0.2036 1.09 0.777 1.52 -0.0399 0.182 0.826 0.08281 0.961 0.672 1.37 PRS_PLINK_0.0199526231496888 FALSE 743.21 Pathologic fracture of vertebrae Both 127 919 14 musculoskeletal darkolivegreen 919, 127 230, 25 230, 25 229, 42 230, 35 0.0939 0.0946 0.32 0.4942 1.1 0.913 1.32 -0.1 0.297 0.736 0.133 0.905 0.505 1.62 0.441 0.27 0.102 0.9913 1.55 0.916 2.64 0.288 0.286 0.315 0.5016 1.33 0.761 2.34 PRS_PLINK_0.0199526231496888 FALSE 743.22 Pathologic fracture of femur Both 32 308 14 musculoskeletal darkolivegreen 308, 32 77, 4 77, 8 77, 10 77, 10 0.239 0.196 0.222 0.6543 1.27 0.866 1.86 0.541 0.584 0.354 0.451 1.72 0.547 5.39 0.896 0.561 0.11 0.9583 2.45 0.816 7.35 0.938 0.577 0.104 0.983 2.55 0.825 7.91 PRS_PLINK_0.0199526231496888 TRUE 743.4 Stress fracture Both 125 1151 14 musculoskeletal darkolivegreen 1151, 125 288, 33 288, 37 287, 21 288, 34 -0.0287 0.0989 0.772 0.1125 0.972 0.8 1.18 0.0909 0.252 0.719 0.1435 1.1 0.668 1.8 -0.451 0.294 0.126 0.9004 0.637 0.358 1.13 0.0838 0.269 0.756 0.1216 1.09 0.641 1.84 PRS_PLINK_0.0199526231496888 FALSE 743.9 Osteopenia or other disorder of bone and cartilage Both 1761 9540 14 musculoskeletal darkolivegreen 9540, 1761 2385, 462 2385, 470 2385, 409 2385, 420 -0.00875 0.0272 0.747 0.1265 0.991 0.94 1.05 0.0572 0.0739 0.439 0.3572 1.06 0.916 1.22 -0.0823 0.0763 0.281 0.552 0.921 0.793 1.07 0.0244 0.0782 0.755 0.1223 1.02 0.879 1.19 PRS_PLINK_0.0199526231496888 FALSE 745 Pain in joint Both 5453 7378 14 musculoskeletal darkolivegreen 7378, 5453 1845, 1414 1844, 1394 1844, 1361 1845, 1283 -0.032 0.0185 0.0832 1.08 0.968 0.934 1 -0.00182 0.0506 0.971 0.01261 0.998 0.904 1.1 -0.0329 0.0515 0.523 0.2818 0.968 0.875 1.07 -0.0864 0.0535 0.106 0.9732 0.917 0.826 1.02 PRS_PLINK_0.0199526231496888 FALSE 747 Cardiac and circulatory congenital anomalies Both 833 5493 15 congenital anomalies mediumspringgreen 5493, 833 1374, 205 1373, 203 1373, 204 1373, 221 0.0267 0.0381 0.483 0.3162 1.03 0.953 1.11 -0.00512 0.107 0.962 0.01698 0.995 0.807 1.23 -0.00791 0.108 0.942 0.02616 0.992 0.803 1.23 0.0583 0.11 0.597 0.2238 1.06 0.854 1.32 PRS_PLINK_0.0199526231496888 FALSE 747.1 Cardiac congenital anomalies Both 680 4182 15 congenital anomalies mediumspringgreen 4182, 680 1046, 165 1045, 158 1045, 167 1046, 190 0.0697 0.0424 0.101 0.9975 1.07 0.987 1.17 -0.0309 0.12 0.798 0.09824 0.97 0.766 1.23 0.00234 0.12 0.984 0.006813 1 0.792 1.27 0.131 0.121 0.283 0.5487 1.14 0.898 1.45 PRS_PLINK_0.0199526231496888 FALSE 747.11 Cardiac shunt/ heart septal defect Both 289 1727 15 congenital anomalies mediumspringgreen 1727, 289 432, 72 432, 69 431, 67 432, 81 0.0772 0.0652 0.237 0.6255 1.08 0.951 1.23 -0.0285 0.182 0.875 0.05775 0.972 0.68 1.39 -0.119 0.186 0.522 0.2825 0.888 0.617 1.28 0.134 0.184 0.464 0.3334 1.14 0.798 1.64 PRS_PLINK_0.0199526231496888 FALSE 747.12 Valvular heart disease/ heart chambers Both 281 1584 15 congenital anomalies mediumspringgreen 1584, 281 396, 67 396, 72 396, 67 396, 75 0.0377 0.067 0.573 0.2415 1.04 0.911 1.18 0.0749 0.186 0.687 0.1629 1.08 0.749 1.55 -0.049 0.189 0.796 0.09921 0.952 0.657 1.38 0.0316 0.193 0.87 0.06033 1.03 0.707 1.51 PRS_PLINK_0.0199526231496888 FALSE 747.13 Congenital anomalies of great vessels Both 152 899 15 congenital anomalies mediumspringgreen 899, 152 225, 40 225, 34 224, 37 225, 41 0.0803 0.0862 0.352 0.454 1.08 0.915 1.28 -0.0924 0.253 0.715 0.1459 0.912 0.556 1.5 -0.0616 0.25 0.806 0.09385 0.94 0.576 1.54 0.101 0.256 0.694 0.1588 1.11 0.669 1.83 PRS_PLINK_0.0199526231496888 FALSE 747.2 Congenital anomalies of peripheral vascular system Both 173 1411 15 congenital anomalies mediumspringgreen 1411, 173 353, 41 353, 43 352, 49 353, 40 0.0136 0.0829 0.869 0.06082 1.01 0.862 1.19 0.0104 0.23 0.964 0.01592 1.01 0.644 1.58 0.266 0.232 0.251 0.6001 1.3 0.829 2.05 -0.044 0.246 0.858 0.06657 0.957 0.591 1.55 PRS_PLINK_0.0199526231496888 FALSE 748 Anomalies of respiratory system, congenital Both 35 312 15 congenital anomalies mediumspringgreen 312, 35 78, 7 78, 7 78, 9 78, 12 0.184 0.184 0.318 0.4975 1.2 0.838 1.72 -0.143 0.52 0.782 0.1066 0.866 0.313 2.4 0.342 0.515 0.507 0.2952 1.41 0.513 3.86 0.623 0.53 0.24 0.6205 1.87 0.66 5.27 PRS_PLINK_0.0199526231496888 TRUE 749 Congenital anomalies of face and neck Both 189 1847 15 congenital anomalies mediumspringgreen 1847, 189 462, 46 462, 46 461, 55 462, 42 0.0684 0.0783 0.382 0.4176 1.07 0.918 1.25 0.0268 0.218 0.902 0.04474 1.03 0.67 1.58 0.181 0.213 0.394 0.404 1.2 0.79 1.82 -0.0646 0.235 0.783 0.1061 0.937 0.592 1.49 PRS_PLINK_0.0199526231496888 FALSE 749.1 Cleft palate Both 35 362 15 congenital anomalies mediumspringgreen 362, 35 91, 7 90, 11 90, 11 91, 6 0.0269 0.179 0.881 0.05522 1.03 0.723 1.46 0.494 0.478 0.301 0.5209 1.64 0.642 4.18 0.427 0.486 0.38 0.4205 1.53 0.591 3.98 -0.18 0.558 0.747 0.1267 0.835 0.28 2.49 PRS_PLINK_0.0199526231496888 TRUE 749.2 Congenital anomalies of skull and face bones Both 40 378 15 congenital anomalies mediumspringgreen 378, 40 95, 11 94, 11 94, 10 95, 8 -0.00841 0.167 0.96 0.01778 0.992 0.715 1.38 0.0496 0.436 0.91 0.04117 1.05 0.447 2.47 0.143 0.467 0.759 0.1196 1.15 0.462 2.88 -0.494 0.53 0.351 0.4545 0.61 0.216 1.72 PRS_PLINK_0.0199526231496888 TRUE 750 Digestive congenital anomalies Both 279 2376 15 congenital anomalies mediumspringgreen 2376, 279 593, 68 594, 73 594, 62 594, 76 0.0948 0.0654 0.147 0.832 1.1 0.967 1.25 0.124 0.178 0.486 0.313 1.13 0.799 1.6 -0.0638 0.186 0.732 0.1354 0.938 0.651 1.35 0.152 0.182 0.404 0.394 1.16 0.815 1.66 PRS_PLINK_0.0199526231496888 FALSE 750.1 Upper gastrointestinal congenital anomalies Both 105 921 15 congenital anomalies mediumspringgreen 921, 105 230, 31 230, 26 230, 21 230, 27 -0.0235 0.105 0.823 0.0846 0.977 0.795 1.2 -0.144 0.28 0.607 0.2169 0.866 0.5 1.5 -0.21 0.306 0.492 0.3085 0.81 0.445 1.47 -0.0989 0.288 0.732 0.1357 0.906 0.515 1.59 PRS_PLINK_0.0199526231496888 FALSE 750.11 Esophageal atresia/tracheoesophageal fistula Both 36 273 15 congenital anomalies mediumspringgreen 273, 36 69, 14 68, 9 68, 5 68, 8 -0.225 0.185 0.223 0.6512 0.799 0.556 1.15 -0.264 0.458 0.564 0.2488 0.768 0.313 1.88 -0.816 0.538 0.129 0.8893 0.442 0.154 1.27 -0.348 0.477 0.466 0.3315 0.706 0.277 1.8 PRS_PLINK_0.0199526231496888 TRUE 750.13 Congenital anomalies of mouth/tongue Both 31 320 15 congenital anomalies mediumspringgreen 320, 31 79, 10 80, 6 80, 8 80, 7 0.0294 0.18 0.87 0.06035 1.03 0.723 1.47 -0.369 0.501 0.462 0.3353 0.692 0.259 1.85 -0.0922 0.498 0.853 0.06895 0.912 0.343 2.42 0.0455 0.525 0.931 0.03108 1.05 0.374 2.93 PRS_PLINK_0.0199526231496888 TRUE 750.14 Congenital anomalies of esophagus Both 38 297 15 congenital anomalies mediumspringgreen 297, 38 75, 12 74, 10 74, 11 74, 5 -0.289 0.184 0.117 0.9321 0.749 0.522 1.07 -0.0154 0.474 0.974 0.01141 0.985 0.389 2.49 0.205 0.478 0.668 0.1753 1.23 0.481 3.13 -0.712 0.561 0.204 0.6894 0.49 0.163 1.47 PRS_PLINK_0.0199526231496888 TRUE 750.15 Congenital anomalies of stomach Both 15 110 15 congenital anomalies mediumspringgreen 110, 15 28, 3 27, 0 27, 6 28, 6 0.747 0.314 0.0174 1.759 2.11 1.14 3.91 -1.82 1.28 0.155 0.8103 0.162 0.0131 1.99 1.56 0.964 0.105 0.9775 4.77 0.72 31.5 0.321 0.78 0.68 0.1672 1.38 0.299 6.37 PRS_PLINK_0.0199526231496888 TRUE 750.2 Lower gastrointestinal congenital anomalies Both 172 1453 15 congenital anomalies mediumspringgreen 1453, 172 364, 41 363, 42 363, 42 363, 47 0.108 0.0842 0.198 0.7038 1.11 0.945 1.31 0.0565 0.23 0.806 0.09362 1.06 0.674 1.66 0.0235 0.232 0.919 0.03665 1.02 0.65 1.61 0.14 0.233 0.547 0.2619 1.15 0.729 1.81 PRS_PLINK_0.0199526231496888 FALSE 750.21 Congenital anomalies of intestine Both 96 817 15 congenital anomalies mediumspringgreen 817, 96 205, 22 204, 23 204, 29 204, 22 0.0903 0.112 0.419 0.378 1.09 0.879 1.36 0.0796 0.31 0.797 0.0985 1.08 0.59 1.99 0.315 0.302 0.296 0.5288 1.37 0.759 2.48 -0.0693 0.318 0.828 0.08208 0.933 0.5 1.74 PRS_PLINK_0.0199526231496888 FALSE 750.22 Congenital anomaly of gallbladder, bile ducts, liver, pancreas Both 79 622 15 congenital anomalies mediumspringgreen 622, 79 156, 19 155, 21 155, 15 156, 24 0.11 0.12 0.359 0.4443 1.12 0.882 1.41 0.131 0.333 0.693 0.1593 1.14 0.594 2.19 -0.379 0.363 0.296 0.529 0.685 0.336 1.39 0.236 0.329 0.474 0.3243 1.27 0.664 2.41 PRS_PLINK_0.0199526231496888 FALSE 751 Genitourinary congenital anomalies Both 564 5625 15 congenital anomalies mediumspringgreen 5625, 564 1406, 135 1406, 137 1406, 141 1406, 151 0.0691 0.0451 0.126 0.8999 1.07 0.981 1.17 0.00405 0.127 0.974 0.01124 1 0.783 1.29 0.0231 0.128 0.857 0.06725 1.02 0.797 1.31 0.157 0.129 0.226 0.646 1.17 0.908 1.51 PRS_PLINK_0.0199526231496888 FALSE 751.1 Congenital anomalies of genital organs Both 200 1978 15 congenital anomalies mediumspringgreen 1978, 200 494, 43 494, 60 494, 46 495, 51 0.031 0.0753 0.681 0.1671 1.03 0.89 1.2 0.364 0.208 0.0803 1.095 1.44 0.957 2.16 0.0576 0.222 0.795 0.09951 1.06 0.686 1.64 0.287 0.225 0.202 0.694 1.33 0.857 2.07 PRS_PLINK_0.0199526231496888 FALSE 751.11 Congenital anomalies of female genital organs Female 165 1571 15 congenital anomalies mediumspringgreen 1571, 165 392, 38 393, 53 392, 34 393, 40 -0.0432 0.0822 0.599 0.2227 0.958 0.815 1.13 0.327 0.222 0.141 0.8518 1.39 0.898 2.14 -0.132 0.246 0.59 0.2292 0.876 0.541 1.42 0.0977 0.246 0.691 0.1604 1.1 0.681 1.79 PRS_PLINK_0.0199526231496888 FALSE 751.12 Congenital anomalies of male genital organs Male 28 329 15 congenital anomalies mediumspringgreen 329, 28 83, 5 82, 7 82, 7 82, 9 0.397 0.211 0.0601 1.221 1.49 0.983 2.25 0.321 0.544 0.555 0.2561 1.38 0.475 4 0.329 0.603 0.585 0.233 1.39 0.426 4.53 0.728 0.595 0.221 0.6554 2.07 0.645 6.65 PRS_PLINK_0.0199526231496888 TRUE 751.2 Congenital anomalies of urinary system Both 339 3498 15 congenital anomalies mediumspringgreen 3498, 339 875, 85 874, 79 874, 84 875, 91 0.0552 0.0571 0.334 0.4763 1.06 0.945 1.18 -0.0687 0.162 0.672 0.1725 0.934 0.679 1.28 -0.0162 0.162 0.921 0.03587 0.984 0.716 1.35 0.13 0.164 0.427 0.3694 1.14 0.826 1.57 PRS_PLINK_0.0199526231496888 FALSE 751.21 Cystic kidney disease Both 202 2332 15 congenital anomalies mediumspringgreen 2332, 202 583, 56 583, 45 583, 43 583, 58 0.0438 0.0732 0.55 0.2598 1.04 0.905 1.21 -0.233 0.207 0.262 0.5815 0.792 0.528 1.19 -0.229 0.212 0.281 0.5508 0.796 0.525 1.21 0.0658 0.204 0.747 0.1267 1.07 0.716 1.59 PRS_PLINK_0.0199526231496888 FALSE 751.22 Other specified congenital anomalies of kidney Both 87 795 15 congenital anomalies mediumspringgreen 795, 87 199, 21 199, 19 198, 28 199, 19 0.059 0.113 0.602 0.2204 1.06 0.85 1.32 -0.0811 0.323 0.802 0.09599 0.922 0.49 1.74 0.298 0.302 0.324 0.4891 1.35 0.745 2.44 -0.0315 0.336 0.925 0.03373 0.969 0.502 1.87 PRS_PLINK_0.0199526231496888 FALSE 751.3 Obstructive genitourinary defect Both 73 597 15 congenital anomalies mediumspringgreen 597, 73 150, 18 149, 20 149, 19 149, 16 -0.0444 0.13 0.732 0.1356 0.957 0.742 1.23 0.161 0.34 0.635 0.1969 1.18 0.603 2.29 -0.00411 0.353 0.991 0.004055 0.996 0.498 1.99 -0.224 0.376 0.551 0.259 0.799 0.383 1.67 PRS_PLINK_0.0199526231496888 FALSE 752 Nervous system congenital anomalies Both 312 2934 15 congenital anomalies mediumspringgreen 2934, 312 734, 92 733, 64 733, 79 734, 77 -0.0304 0.0605 0.616 0.2107 0.97 0.862 1.09 -0.398 0.17 0.0196 1.709 0.672 0.481 0.938 -0.149 0.163 0.363 0.4401 0.862 0.626 1.19 -0.19 0.169 0.261 0.5829 0.827 0.593 1.15 PRS_PLINK_0.0199526231496888 FALSE 752.1 Neural tube defects Both 235 2287 15 congenital anomalies mediumspringgreen 2287, 235 572, 68 572, 48 571, 61 572, 58 0.01 0.0688 0.884 0.05345 1.01 0.883 1.16 -0.396 0.197 0.0447 1.35 0.673 0.457 0.991 -0.134 0.187 0.475 0.3229 0.875 0.606 1.26 -0.162 0.195 0.408 0.3896 0.851 0.58 1.25 PRS_PLINK_0.0199526231496888 FALSE 752.11 Spina bifida Both 72 625 15 congenital anomalies mediumspringgreen 625, 72 157, 23 156, 12 156, 20 156, 17 -0.0785 0.125 0.531 0.2749 0.924 0.723 1.18 -0.644 0.363 0.0757 1.121 0.525 0.258 1.07 -0.102 0.325 0.755 0.122 0.903 0.477 1.71 -0.282 0.35 0.42 0.3766 0.754 0.38 1.5 PRS_PLINK_0.0199526231496888 FALSE 752.2 Other specified congenital anomalies of nervous system Both 86 754 15 congenital anomalies mediumspringgreen 754, 86 189, 30 188, 15 188, 22 189, 19 -0.167 0.119 0.16 0.7953 0.847 0.671 1.07 -0.685 0.323 0.0338 1.471 0.504 0.268 0.949 -0.357 0.297 0.229 0.6398 0.7 0.391 1.25 -0.528 0.319 0.0978 1.01 0.59 0.315 1.1 PRS_PLINK_0.0199526231496888 FALSE 753 Congenital anomalies of the eye Both 39 530 15 congenital anomalies mediumspringgreen 530, 39 133, 11 132, 8 132, 12 133, 8 0.0196 0.158 0.901 0.04505 1.02 0.748 1.39 -0.303 0.455 0.505 0.2966 0.738 0.303 1.8 0.174 0.43 0.685 0.1642 1.19 0.512 2.77 -0.266 0.468 0.57 0.2444 0.766 0.306 1.92 PRS_PLINK_0.0199526231496888 TRUE 753.1 Congenital cataract and lens anomalies Both 11 138 15 congenital anomalies mediumspringgreen 138, 11 35, 4 34, 1 34, 3 35, 3 0.198 0.289 0.493 0.3068 1.22 0.692 2.15 -1.66 1.04 0.108 0.9657 0.189 0.0249 1.44 -0.203 0.758 0.789 0.1029 0.816 0.185 3.61 -0.216 0.805 0.789 0.1032 0.806 0.167 3.9 PRS_PLINK_0.0199526231496888 TRUE 753.2 Congenital anomalies of posterior segment of eye Both 17 154 15 congenital anomalies mediumspringgreen 154, 17 39, 5 38, 9 38, 0 39, 3 -0.265 0.264 0.316 0.5005 0.767 0.457 1.29 0.47 0.594 0.428 0.3681 1.6 0.5 5.13 -2.85 1.43 0.0455 1.342 0.0576 0.00351 0.945 -0.559 0.683 0.412 0.3846 0.572 0.15 2.18 PRS_PLINK_0.0199526231496888 TRUE 754 Congenital musculoskeletal deformities of spine Both 302 2806 15 congenital anomalies mediumspringgreen 2806, 302 702, 77 701, 74 701, 74 702, 77 0.0494 0.0626 0.43 0.3664 1.05 0.929 1.19 -0.0736 0.171 0.666 0.1766 0.929 0.665 1.3 -0.0206 0.173 0.905 0.04325 0.98 0.699 1.37 0.0316 0.176 0.857 0.06698 1.03 0.732 1.46 PRS_PLINK_0.0199526231496888 FALSE 754.1 Lumbosacral spondylolysis, congenital Both 35 332 15 congenital anomalies mediumspringgreen 332, 35 83, 4 83, 12 83, 4 83, 15 0.333 0.194 0.0861 1.065 1.4 0.954 2.04 0.935 0.542 0.0847 1.072 2.55 0.88 7.37 -0.0694 0.626 0.912 0.04013 0.933 0.273 3.18 1.28 0.555 0.0214 1.67 3.59 1.21 10.7 PRS_PLINK_0.0199526231496888 TRUE 754.2 Spondylolisthesis, congenital Both 151 1314 15 congenital anomalies mediumspringgreen 1314, 151 329, 40 328, 34 328, 37 329, 40 0.0787 0.0878 0.37 0.4315 1.08 0.911 1.29 -0.153 0.243 0.53 0.2758 0.858 0.533 1.38 -0.0732 0.244 0.764 0.1169 0.929 0.576 1.5 -0.00605 0.245 0.98 0.008652 0.994 0.615 1.61 PRS_PLINK_0.0199526231496888 FALSE 755 Congenital anomalies of limbs Both 273 2436 15 congenital anomalies mediumspringgreen 2436, 273 609, 79 609, 55 609, 67 609, 72 0.00992 0.0663 0.881 0.05499 1.01 0.887 1.15 -0.348 0.184 0.0582 1.235 0.706 0.492 1.01 -0.183 0.178 0.302 0.5198 0.832 0.588 1.18 -0.171 0.181 0.345 0.462 0.843 0.591 1.2 PRS_PLINK_0.0199526231496888 FALSE 755.1 Congenital deformities of feet Both 101 1042 15 congenital anomalies mediumspringgreen 1042, 101 261, 26 260, 21 260, 29 261, 25 0.0467 0.107 0.662 0.1793 1.05 0.85 1.29 -0.159 0.298 0.594 0.2261 0.853 0.476 1.53 0.148 0.285 0.603 0.2195 1.16 0.663 2.03 -0.023 0.308 0.94 0.02667 0.977 0.535 1.79 PRS_PLINK_0.0199526231496888 FALSE 755.4 Congenital anomalies of upper limb, including shoulder girdle Both 28 227 15 congenital anomalies mediumspringgreen 227, 28 57, 8 57, 8 56, 7 57, 5 0.0118 0.191 0.951 0.02202 1.01 0.696 1.47 0.0731 0.529 0.89 0.05057 1.08 0.381 3.03 -0.0886 0.559 0.874 0.05843 0.915 0.306 2.74 -0.769 0.642 0.231 0.6357 0.464 0.132 1.63 PRS_PLINK_0.0199526231496888 TRUE 755.6 Other congenital anomalies of lower limb, including pelvic girdle Both 156 1229 15 congenital anomalies mediumspringgreen 1229, 156 308, 48 307, 25 307, 36 307, 47 0.0359 0.0909 0.693 0.1591 1.04 0.867 1.24 -0.63 0.255 0.0135 1.87 0.533 0.323 0.878 -0.257 0.237 0.278 0.5565 0.773 0.486 1.23 -0.0878 0.232 0.705 0.1516 0.916 0.581 1.44 PRS_PLINK_0.0199526231496888 FALSE 755.61 Congenital hip dysplasia and deformity Both 108 783 15 congenital anomalies mediumspringgreen 783, 108 196, 33 196, 19 195, 23 196, 33 -0.00229 0.109 0.983 0.007321 0.998 0.805 1.24 -0.528 0.3 0.0786 1.105 0.59 0.328 1.06 -0.38 0.29 0.19 0.7216 0.684 0.388 1.21 -0.121 0.277 0.664 0.1779 0.886 0.515 1.53 PRS_PLINK_0.0199526231496888 FALSE 756 Other congenital musculoskeletal anomalies Both 455 4000 15 congenital anomalies mediumspringgreen 4000, 455 999, 124 1000, 113 1000, 118 1000, 100 -0.0392 0.0509 0.441 0.3557 0.962 0.87 1.06 -0.12 0.138 0.384 0.4155 0.887 0.677 1.16 -0.101 0.138 0.464 0.3334 0.904 0.689 1.19 -0.274 0.149 0.0662 1.179 0.76 0.567 1.02 PRS_PLINK_0.0199526231496888 FALSE 756.1 Congenital anomalies of abdominal wall; diaphram Both 32 239 15 congenital anomalies mediumspringgreen 239, 32 59, 6 60, 8 59, 13 60, 5 0.144 0.19 0.449 0.3481 1.16 0.795 1.68 0.155 0.543 0.775 0.1108 1.17 0.403 3.38 0.699 0.524 0.182 0.7389 2.01 0.72 5.62 -0.255 0.61 0.676 0.1699 0.775 0.234 2.56 PRS_PLINK_0.0199526231496888 TRUE 756.2 Pectus and other congenital anomalies of ribs/sternum Both 32 210 15 congenital anomalies mediumspringgreen 210, 32 53, 9 52, 11 52, 5 53, 7 -0.121 0.201 0.548 0.2611 0.886 0.598 1.31 0.179 0.498 0.719 0.1433 1.2 0.45 3.18 -0.581 0.607 0.338 0.4712 0.559 0.17 1.84 -0.412 0.579 0.477 0.3217 0.662 0.213 2.06 PRS_PLINK_0.0199526231496888 TRUE 756.3 Congenital anomalies of muscle, tendon, fascia, and connective tissue Both 116 1020 15 congenital anomalies mediumspringgreen 1020, 116 255, 28 255, 33 255, 27 255, 28 -0.0951 0.0988 0.336 0.4738 0.909 0.749 1.1 0.0919 0.269 0.733 0.1352 1.1 0.647 1.86 -0.12 0.285 0.675 0.1708 0.887 0.507 1.55 -0.0733 0.294 0.803 0.09525 0.929 0.523 1.65 PRS_PLINK_0.0199526231496888 FALSE 756.5 Congenital osteodystrophies Both 282 2641 15 congenital anomalies mediumspringgreen 2641, 282 661, 78 660, 69 660, 71 660, 64 -0.0269 0.0642 0.675 0.1704 0.973 0.858 1.1 -0.135 0.174 0.437 0.3591 0.874 0.622 1.23 -0.127 0.175 0.468 0.3295 0.881 0.625 1.24 -0.244 0.187 0.191 0.7189 0.783 0.543 1.13 PRS_PLINK_0.0199526231496888 FALSE 757 Congenital anomalies of the integument Both 101 916 15 congenital anomalies mediumspringgreen 916, 101 229, 27 229, 20 229, 30 229, 24 -0.0212 0.106 0.841 0.07503 0.979 0.795 1.2 -0.302 0.303 0.319 0.496 0.74 0.409 1.34 0.0733 0.278 0.792 0.1011 1.08 0.624 1.86 -0.129 0.305 0.673 0.1723 0.879 0.484 1.6 PRS_PLINK_0.0199526231496888 FALSE 758 Chromosomal anomalies and genetic disorders Both 80 613 15 congenital anomalies mediumspringgreen 613, 80 154, 22 153, 18 153, 19 153, 21 0.0671 0.127 0.596 0.2249 1.07 0.835 1.37 -0.225 0.332 0.499 0.302 0.799 0.417 1.53 -0.152 0.333 0.649 0.1875 0.859 0.447 1.65 -0.0348 0.343 0.919 0.03656 0.966 0.493 1.89 PRS_PLINK_0.0199526231496888 FALSE 758.1 Chromosomal anomalies Both 53 485 15 congenital anomalies mediumspringgreen 485, 53 122, 14 121, 13 121, 11 121, 15 0.102 0.148 0.492 0.3084 1.11 0.829 1.48 0.0567 0.393 0.885 0.05288 1.06 0.49 2.29 -0.174 0.409 0.67 0.174 0.84 0.377 1.87 0.256 0.4 0.521 0.283 1.29 0.59 2.83 PRS_PLINK_0.0199526231496888 FALSE 759 Other and unspecified congenital anomalies Both 224 1902 15 congenital anomalies mediumspringgreen 1902, 224 476, 53 475, 47 475, 62 476, 62 0.0693 0.0742 0.35 0.4561 1.07 0.927 1.24 -0.168 0.21 0.425 0.3718 0.846 0.56 1.28 0.175 0.2 0.38 0.4198 1.19 0.805 1.76 0.145 0.206 0.484 0.3155 1.16 0.771 1.73 PRS_PLINK_0.0199526231496888 FALSE 759.1 Anomalies of endocrine glands, congenital Both 24 266 15 congenital anomalies mediumspringgreen 266, 24 67, 3 66, 8 66, 7 67, 6 0.0666 0.215 0.757 0.121 1.07 0.701 1.63 1.39 0.734 0.0589 1.23 4 0.949 16.8 0.782 0.692 0.258 0.5881 2.19 0.564 8.48 0.165 0.735 0.822 0.08517 1.18 0.28 4.98 PRS_PLINK_0.0199526231496888 TRUE 760 Back pain Both 4435 8391 17 symptoms purple 8391, 4435 2098, 1158 2098, 1111 2097, 1069 2098, 1096 -0.00764 0.0193 0.692 0.1599 0.992 0.956 1.03 -0.0325 0.0529 0.54 0.268 0.968 0.873 1.07 -0.0742 0.0539 0.168 0.7739 0.928 0.835 1.03 -0.026 0.0553 0.638 0.1949 0.974 0.874 1.09 PRS_PLINK_0.0199526231496888 FALSE 761 Cervicalgia Both 1851 10848 17 symptoms purple 10848, 1851 2711, 518 2712, 463 2712, 460 2712, 410 -0.0405 0.0262 0.121 0.9169 0.96 0.912 1.01 -0.0992 0.0703 0.159 0.7998 0.906 0.789 1.04 -0.0984 0.0714 0.168 0.7746 0.906 0.788 1.04 -0.179 0.0753 0.0176 1.754 0.836 0.721 0.969 PRS_PLINK_0.0199526231496888 FALSE 763 Thoracic or lumbosacral neuritis or radiculitis, unspecified Both 816 8300 17 symptoms purple 8300, 816 2075, 213 2075, 216 2075, 196 2075, 191 -0.0529 0.0377 0.16 0.7946 0.948 0.881 1.02 0.0197 0.102 0.846 0.07242 1.02 0.836 1.24 -0.0624 0.105 0.554 0.2568 0.94 0.764 1.15 -0.0877 0.109 0.421 0.3753 0.916 0.74 1.13 PRS_PLINK_0.0199526231496888 FALSE 764 Sciatica Both 847 8472 17 symptoms purple 8472, 847 2118, 216 2118, 202 2118, 214 2118, 215 0.0101 0.0369 0.783 0.106 1.01 0.94 1.09 -0.0685 0.103 0.505 0.2969 0.934 0.763 1.14 0.00617 0.103 0.952 0.02134 1.01 0.823 1.23 0.0214 0.105 0.839 0.07603 1.02 0.831 1.26 PRS_PLINK_0.0199526231496888 FALSE 765 Cervical radiculitis Both 419 4583 17 symptoms purple 4583, 419 1146, 127 1146, 113 1145, 92 1146, 87 -0.0998 0.0522 0.0561 1.251 0.905 0.817 1 -0.0971 0.136 0.475 0.3238 0.907 0.695 1.18 -0.298 0.145 0.0397 1.401 0.742 0.558 0.986 -0.303 0.151 0.0456 1.341 0.739 0.549 0.994 PRS_PLINK_0.0199526231496888 FALSE 766 Neuralgia, neuritis, and radiculitis NOS Both 1278 10134 17 symptoms purple 10134, 1278 2533, 348 2533, 333 2533, 295 2534, 302 -0.0588 0.0306 0.0544 1.265 0.943 0.888 1 -0.0358 0.0822 0.663 0.1785 0.965 0.821 1.13 -0.14 0.0856 0.102 0.9916 0.869 0.735 1.03 -0.0837 0.0877 0.34 0.4687 0.92 0.774 1.09 PRS_PLINK_0.0199526231496888 FALSE 767 Cervicocranial/Cervicobrachial syndrome Both 36 341 17 symptoms purple 341, 36 86, 11 85, 10 85, 7 85, 8 0.0127 0.174 0.942 0.02601 1.01 0.72 1.42 -0.0768 0.451 0.865 0.06306 0.926 0.382 2.24 -0.334 0.486 0.492 0.3081 0.716 0.276 1.86 -0.225 0.474 0.635 0.197 0.799 0.315 2.02 PRS_PLINK_0.0199526231496888 TRUE 769 Nonallopathic lesions NEC Both 319 3123 17 symptoms purple 3123, 319 781, 83 781, 82 780, 79 781, 75 -0.0171 0.0603 0.777 0.1098 0.983 0.873 1.11 -0.00792 0.163 0.961 0.01719 0.992 0.721 1.37 -0.0543 0.167 0.745 0.1279 0.947 0.683 1.31 -0.092 0.173 0.594 0.2262 0.912 0.65 1.28 PRS_PLINK_0.0199526231496888 FALSE 770 Myalgia and myositis unspecified Both 1671 9730 17 symptoms purple 9730, 1671 2433, 408 2432, 412 2432, 443 2433, 407 0.0156 0.0276 0.571 0.2435 1.02 0.962 1.07 0.00236 0.0763 0.975 0.01084 1 0.863 1.16 0.085 0.0762 0.265 0.5767 1.09 0.938 1.26 -0.0228 0.0803 0.777 0.1096 0.977 0.835 1.14 PRS_PLINK_0.0199526231496888 FALSE 771 Musculoskeletal symptoms referable to limbs Both 1255 9695 17 symptoms purple 9695, 1255 2424, 298 2424, 315 2423, 306 2424, 335 0.0637 0.0309 0.0396 1.402 1.07 1 1.13 0.0868 0.0864 0.315 0.5012 1.09 0.921 1.29 0.0643 0.0881 0.465 0.3321 1.07 0.897 1.27 0.197 0.0893 0.0277 1.558 1.22 1.02 1.45 PRS_PLINK_0.0199526231496888 FALSE 771.1 Swelling of limb Both 1526 9620 17 symptoms purple 9620, 1526 2405, 365 2405, 389 2405, 367 2405, 404 0.068 0.0286 0.0174 1.76 1.07 1.01 1.13 0.0982 0.0794 0.216 0.6655 1.1 0.944 1.29 0.0238 0.0815 0.77 0.1133 1.02 0.873 1.2 0.184 0.0825 0.0256 1.592 1.2 1.02 1.41 PRS_PLINK_0.0199526231496888 FALSE 771.2 Cramp of limb Both 262 2490 17 symptoms purple 2490, 262 623, 77 622, 63 622, 61 623, 61 -0.0551 0.0683 0.419 0.3773 0.946 0.828 1.08 -0.203 0.178 0.253 0.596 0.816 0.575 1.16 -0.255 0.182 0.16 0.7964 0.775 0.543 1.11 -0.265 0.187 0.157 0.8046 0.767 0.532 1.11 PRS_PLINK_0.0199526231496888 FALSE 772 Symptoms of the muscles Both 612 5456 17 symptoms purple 5456, 612 1364, 177 1364, 164 1364, 131 1364, 140 -0.0868 0.0444 0.0506 1.296 0.917 0.84 1 -0.0945 0.115 0.413 0.3841 0.91 0.726 1.14 -0.324 0.123 0.0087 2.06 0.724 0.568 0.921 -0.291 0.125 0.0201 1.697 0.748 0.585 0.955 PRS_PLINK_0.0199526231496888 FALSE 772.1 Muscular wasting and disuse atrophy Both 118 1098 17 symptoms purple 1098, 118 275, 19 274, 41 274, 27 275, 31 0.082 0.101 0.415 0.382 1.09 0.891 1.32 0.756 0.285 0.00786 2.104 2.13 1.22 3.72 0.357 0.308 0.248 0.6061 1.43 0.78 2.61 0.352 0.318 0.27 0.5694 1.42 0.762 2.65 PRS_PLINK_0.0199526231496888 FALSE 772.2 Spasm of muscle Both 695 6782 17 symptoms purple 6782, 695 1696, 195 1695, 149 1695, 186 1696, 165 -0.00314 0.041 0.939 0.0274 0.997 0.92 1.08 -0.269 0.114 0.0186 1.731 0.765 0.611 0.956 -0.0474 0.11 0.667 0.1761 0.954 0.769 1.18 -0.135 0.116 0.244 0.6119 0.874 0.696 1.1 PRS_PLINK_0.0199526231496888 FALSE 772.3 Muscle weakness Both 744 6651 17 symptoms purple 6651, 744 1663, 196 1663, 175 1662, 177 1663, 196 -0.00242 0.0396 0.951 0.02172 0.998 0.923 1.08 -0.11 0.11 0.317 0.4991 0.896 0.722 1.11 -0.119 0.111 0.281 0.5506 0.887 0.714 1.1 0.016 0.112 0.886 0.0524 1.02 0.816 1.27 PRS_PLINK_0.0199526231496888 FALSE 772.4 Rhabdomyolysis Both 46 335 17 symptoms purple 335, 46 84, 11 84, 9 83, 15 84, 11 0.143 0.158 0.364 0.4387 1.15 0.847 1.57 -0.118 0.455 0.795 0.09969 0.888 0.364 2.17 0.494 0.434 0.255 0.5936 1.64 0.7 3.83 0.146 0.452 0.747 0.127 1.16 0.477 2.8 PRS_PLINK_0.0199526231496888 TRUE 772.6 Facial weakness Both 101 1103 17 symptoms purple 1103, 101 276, 29 276, 21 275, 27 276, 24 -0.00162 0.103 0.987 0.005502 0.998 0.816 1.22 -0.32 0.29 0.27 0.5681 0.726 0.412 1.28 -0.107 0.278 0.7 0.1551 0.898 0.521 1.55 -0.216 0.292 0.46 0.3374 0.806 0.455 1.43 PRS_PLINK_0.0199526231496888 FALSE 780 Hypothermia/Chills Both 136 1083 17 symptoms purple 1083, 136 271, 42 271, 27 270, 38 271, 29 -0.142 0.0931 0.128 0.8923 0.868 0.723 1.04 -0.406 0.258 0.115 0.9395 0.666 0.402 1.1 -0.144 0.244 0.555 0.2555 0.866 0.537 1.4 -0.372 0.275 0.177 0.7526 0.69 0.402 1.18 PRS_PLINK_0.0199526231496888 FALSE 781 Symptoms involving nervous and musculoskeletal systems Both 620 6185 17 symptoms purple 6185, 620 1547, 169 1546, 127 1546, 172 1546, 151 -0.00966 0.0435 0.824 0.08388 0.99 0.909 1.08 -0.276 0.122 0.0243 1.614 0.759 0.597 0.965 0.0415 0.115 0.719 0.1433 1.04 0.831 1.31 -0.0938 0.122 0.444 0.3528 0.911 0.716 1.16 PRS_PLINK_0.0199526231496888 FALSE 781.1 Loss of height Both 30 242 17 symptoms purple 242, 30 61, 9 60, 6 60, 10 61, 5 -0.35 0.209 0.0947 1.024 0.705 0.467 1.06 -0.601 0.578 0.299 0.5243 0.549 0.177 1.7 -0.263 0.538 0.625 0.2038 0.769 0.268 2.21 -1.16 0.658 0.079 1.103 0.315 0.0867 1.14 PRS_PLINK_0.0199526231496888 TRUE 781.2 Abnormal posture Both 14 147 17 symptoms purple 147, 14 37, 2 37, 3 36, 2 37, 7 0.328 0.234 0.161 0.7934 1.39 0.878 2.2 0.532 0.783 0.497 0.3039 1.7 0.367 7.9 -0.0376 0.83 0.964 0.01598 0.963 0.189 4.9 1.19 0.727 0.103 0.9861 3.27 0.786 13.6 PRS_PLINK_0.0199526231496888 TRUE 782.3 Edema Both 1485 9747 17 symptoms purple 9747, 1485 2437, 369 2437, 342 2436, 384 2437, 389 0.063 0.0289 0.0292 1.534 1.07 1.01 1.13 -0.0448 0.0814 0.582 0.235 0.956 0.815 1.12 0.0549 0.0805 0.495 0.3052 1.06 0.902 1.24 0.0946 0.0828 0.253 0.5966 1.1 0.935 1.29 PRS_PLINK_0.0199526231496888 FALSE 782.6 Pallor and flushing Both 294 3064 17 symptoms purple 3064, 294 766, 69 766, 74 766, 75 766, 76 0.0351 0.0632 0.578 0.238 1.04 0.915 1.17 0.0381 0.174 0.827 0.08254 1.04 0.738 1.46 0.0478 0.176 0.786 0.1046 1.05 0.743 1.48 0.0244 0.18 0.892 0.04947 1.02 0.72 1.46 PRS_PLINK_0.0199526231496888 FALSE 783 Fever of unknown origin Both 1781 10954 17 symptoms purple 10954, 1781 2738, 420 2738, 439 2738, 445 2739, 477 0.0754 0.0264 0.00422 2.375 1.08 1.02 1.14 0.0521 0.0741 0.482 0.3172 1.05 0.911 1.22 0.0647 0.0747 0.387 0.4124 1.07 0.921 1.24 0.15 0.0759 0.0478 1.32 1.16 1 1.35 PRS_PLINK_0.0199526231496888 FALSE 783.1 Postprocedural fever Both 91 721 17 symptoms purple 721, 91 181, 21 180, 17 180, 25 180, 28 0.161 0.117 0.17 0.7704 1.17 0.934 1.48 -0.142 0.343 0.679 0.1679 0.868 0.443 1.7 0.23 0.31 0.459 0.3378 1.26 0.685 2.31 0.261 0.318 0.412 0.3849 1.3 0.696 2.42 PRS_PLINK_0.0199526231496888 FALSE 785 Abdominal pain Both 5150 7679 17 symptoms purple 7679, 5150 1920, 1293 1920, 1270 1919, 1307 1920, 1279 0.0191 0.0187 0.305 0.5153 1.02 0.983 1.06 -0.0118 0.0517 0.819 0.08666 0.988 0.893 1.09 0.012 0.0522 0.818 0.08747 1.01 0.914 1.12 0.0125 0.0539 0.817 0.08803 1.01 0.911 1.13 PRS_PLINK_0.0199526231496888 FALSE 788 Syncope and collapse Both 1224 9533 17 symptoms purple 9533, 1224 2383, 310 2383, 298 2383, 295 2383, 321 0.0432 0.0313 0.167 0.7763 1.04 0.982 1.11 -0.0307 0.0864 0.722 0.1414 0.97 0.819 1.15 -0.0517 0.0879 0.557 0.2545 0.95 0.799 1.13 0.0757 0.089 0.395 0.4038 1.08 0.906 1.28 PRS_PLINK_0.0199526231496888 FALSE 789 Nausea and vomiting Both 3405 9397 17 symptoms purple 9397, 3405 2350, 831 2349, 808 2349, 853 2349, 912 0.0429 0.0208 0.0387 1.412 1.04 1 1.09 -0.0364 0.0582 0.531 0.275 0.964 0.86 1.08 0.031 0.0583 0.595 0.2253 1.03 0.92 1.16 0.088 0.0594 0.139 0.8575 1.09 0.972 1.23 PRS_PLINK_0.0199526231496888 FALSE 789.1 Persistent vomiting Both 266 2396 17 symptoms purple 2396, 266 599, 65 599, 63 599, 72 599, 65 -0.0119 0.0662 0.858 0.06669 0.988 0.868 1.13 -0.0227 0.184 0.902 0.04495 0.978 0.682 1.4 0.168 0.182 0.354 0.4515 1.18 0.829 1.69 0.0441 0.191 0.817 0.08759 1.05 0.719 1.52 PRS_PLINK_0.0199526231496888 FALSE 790 Nonspecific findings on examination of blood Both 628 5347 17 symptoms purple 5347, 628 1337, 140 1337, 153 1336, 150 1337, 184 0.127 0.0433 0.00333 2.477 1.14 1.04 1.24 0.099 0.123 0.421 0.3755 1.1 0.867 1.41 0.0812 0.125 0.517 0.2868 1.08 0.849 1.39 0.329 0.123 0.00764 2.117 1.39 1.09 1.77 PRS_PLINK_0.0199526231496888 FALSE 790.1 Elevated sedimentation rate Both 53 598 17 symptoms purple 598, 53 150, 14 149, 8 149, 16 150, 15 0.065 0.147 0.658 0.1816 1.07 0.8 1.42 -0.472 0.432 0.274 0.5616 0.624 0.267 1.45 0.00576 0.379 0.988 0.005301 1.01 0.479 2.11 0.0249 0.383 0.948 0.02307 1.03 0.484 2.17 PRS_PLINK_0.0199526231496888 FALSE 790.6 Other abnormal blood chemistry Both 1816 10594 17 symptoms purple 10594, 1816 2649, 449 2648, 444 2648, 465 2649, 457 0.0768 0.0265 0.0038 2.421 1.08 1.03 1.14 0.0285 0.0737 0.699 0.1558 1.03 0.891 1.19 0.072 0.074 0.33 0.481 1.07 0.93 1.24 0.0983 0.0764 0.198 0.7026 1.1 0.95 1.28 PRS_PLINK_0.0199526231496888 FALSE 790.8 Elevated C-reactive protein (CRP) Both 80 939 17 symptoms purple 939, 80 235, 20 235, 20 234, 20 235, 20 0.0763 0.12 0.526 0.2793 1.08 0.853 1.37 0.00939 0.317 0.976 0.01037 1.01 0.542 1.88 0.0596 0.318 0.851 0.06984 1.06 0.569 1.98 0.0579 0.332 0.861 0.06475 1.06 0.553 2.03 PRS_PLINK_0.0199526231496888 FALSE 790.9 Abnormal arterial blood gases Both 32 356 17 symptoms purple 356, 32 89, 3 89, 6 89, 7 89, 16 0.624 0.204 0.00227 2.643 1.87 1.25 2.79 0.453 0.627 0.47 0.3283 1.57 0.461 5.38 0.688 0.62 0.267 0.5732 1.99 0.59 6.7 1.48 0.592 0.0126 1.901 4.38 1.37 14 PRS_PLINK_0.0199526231496888 TRUE 791 Gangrene Both 80 643 17 symptoms purple 643, 80 161, 16 161, 23 160, 18 161, 23 0.169 0.113 0.135 0.8682 1.18 0.948 1.48 0.427 0.341 0.21 0.677 1.53 0.786 2.99 0.0566 0.359 0.875 0.05822 1.06 0.524 2.14 0.366 0.356 0.304 0.5171 1.44 0.718 2.89 PRS_PLINK_0.0199526231496888 FALSE 792 Abnormal Papanicolaou smear of cervix and cervical HPV Female 1190 5293 11 genitourinary black 5293, 1190 1323, 302 1323, 323 1323, 275 1323, 290 -0.0219 0.0334 0.513 0.2899 0.978 0.916 1.04 0.0573 0.0895 0.522 0.2821 1.06 0.889 1.26 -0.116 0.0941 0.218 0.6611 0.891 0.741 1.07 -0.0415 0.0954 0.664 0.1779 0.959 0.796 1.16 PRS_PLINK_0.0199526231496888 FALSE 792.1 Papanicolaou smear of cervix or vagina with atypical squamous cells Female 510 4053 11 genitourinary black 4053, 510 1013, 125 1013, 136 1013, 120 1013, 129 0.0191 0.0484 0.694 0.1588 1.02 0.927 1.12 0.0698 0.131 0.595 0.2252 1.07 0.829 1.39 -0.065 0.138 0.637 0.196 0.937 0.715 1.23 -0.0108 0.138 0.938 0.02796 0.989 0.755 1.3 PRS_PLINK_0.0199526231496888 FALSE 794 Abnormal results of other function studies (bladder, pancreas, placenta, spleen, etc) Both 110 1276 17 symptoms purple 1276, 110 319, 31 319, 35 319, 29 319, 15 -0.195 0.0991 0.049 1.31 0.823 0.677 0.999 0.112 0.257 0.664 0.1777 1.12 0.676 1.85 -0.132 0.272 0.628 0.2022 0.876 0.514 1.49 -0.799 0.321 0.0127 1.896 0.45 0.24 0.843 PRS_PLINK_0.0199526231496888 FALSE 795 Other and nonspecific abnormal cytological, histological and immunological findings Both 861 7051 17 symptoms purple 7051, 861 1762, 199 1763, 226 1762, 223 1763, 213 0.00139 0.0375 0.97 0.01303 1 0.93 1.08 0.103 0.103 0.319 0.4968 1.11 0.905 1.36 0.0714 0.105 0.497 0.3039 1.07 0.874 1.32 0.0337 0.109 0.757 0.121 1.03 0.835 1.28 PRS_PLINK_0.0199526231496888 FALSE 795.8 Abnormal tumor markers Both 281 2988 17 symptoms purple 2988, 281 747, 73 747, 79 747, 66 747, 63 -0.0351 0.0631 0.578 0.2379 0.966 0.853 1.09 0.103 0.17 0.544 0.2642 1.11 0.795 1.55 -0.0405 0.179 0.82 0.08596 0.96 0.677 1.36 -0.0844 0.187 0.652 0.1857 0.919 0.637 1.33 PRS_PLINK_0.0199526231496888 FALSE 795.81 Elevated carcinoembryonic antigen [CEA] Both 17 124 17 symptoms purple 124, 17 31, 4 31, 5 31, 1 31, 7 0.231 0.268 0.39 0.409 1.26 0.744 2.13 -0.0906 0.7 0.897 0.0472 0.913 0.231 3.6 -0.673 0.949 0.479 0.3201 0.51 0.0795 3.28 0.615 0.729 0.398 0.3999 1.85 0.444 7.72 PRS_PLINK_0.0199526231496888 TRUE 795.82 Elevated cancer antigen 125 [CA 125] Both 65 558 17 symptoms purple 558, 65 140, 17 139, 14 139, 22 140, 12 -0.0337 0.137 0.806 0.09379 0.967 0.739 1.27 -0.263 0.373 0.482 0.3174 0.769 0.37 1.6 0.151 0.345 0.661 0.1798 1.16 0.591 2.29 -0.458 0.408 0.261 0.583 0.632 0.284 1.41 PRS_PLINK_0.0199526231496888 FALSE 796 Elevated prostate specific antigen [PSA] Male 285 1833 11 genitourinary black 1833, 285 459, 87 458, 78 458, 68 458, 52 -0.114 0.0656 0.0834 1.079 0.893 0.785 1.02 -0.0361 0.173 0.834 0.07872 0.965 0.688 1.35 -0.17 0.18 0.346 0.4615 0.844 0.593 1.2 -0.337 0.197 0.0877 1.057 0.714 0.485 1.05 PRS_PLINK_0.0199526231496888 FALSE 797 Shock Both 292 1256 17 symptoms purple 1256, 292 314, 51 314, 67 314, 80 314, 94 0.309 0.0701 1.04e-05 4.984 1.36 1.19 1.56 0.327 0.204 0.11 0.9604 1.39 0.929 2.07 0.508 0.2 0.0112 1.95 1.66 1.12 2.46 0.666 0.202 0.000974 3.012 1.95 1.31 2.89 PRS_PLINK_0.0199526231496888 FALSE 797.1 Cardiogenic shock Both 154 465 17 symptoms purple 465, 154 117, 27 116, 27 116, 37 116, 63 0.365 0.0985 0.000209 3.681 1.44 1.19 1.75 0.0266 0.304 0.93 0.03132 1.03 0.566 1.86 0.417 0.296 0.159 0.7978 1.52 0.849 2.71 0.797 0.277 0.00397 2.401 2.22 1.29 3.82 PRS_PLINK_0.0199526231496888 FALSE 798 Malaise and fatigue Both 3424 9396 17 symptoms purple 9396, 3424 2348, 925 2349, 812 2349, 845 2349, 842 -0.00854 0.0208 0.681 0.1669 0.991 0.952 1.03 -0.114 0.0571 0.0465 1.332 0.892 0.798 0.998 -0.0835 0.0575 0.146 0.836 0.92 0.822 1.03 -0.0537 0.0592 0.365 0.438 0.948 0.844 1.06 PRS_PLINK_0.0199526231496888 FALSE 798.1 Chronic fatigue syndrome Both 552 4902 17 symptoms purple 4902, 552 1225, 137 1225, 129 1225, 144 1226, 142 0.0384 0.0458 0.402 0.3957 1.04 0.95 1.14 -0.0627 0.129 0.627 0.2031 0.939 0.73 1.21 0.0555 0.127 0.663 0.1783 1.06 0.823 1.36 0.00907 0.132 0.945 0.02451 1.01 0.779 1.31 PRS_PLINK_0.0199526231496888 FALSE 800 Fracture of lower limb Both 582 5978 18 injuries & poisonings gray50 5978, 582 1495, 145 1494, 147 1494, 150 1495, 140 -0.0144 0.0447 0.747 0.1265 0.986 0.903 1.08 0.0183 0.123 0.881 0.05484 1.02 0.801 1.29 0.0076 0.124 0.951 0.02182 1.01 0.791 1.28 0.0374 0.129 0.773 0.1121 1.04 0.805 1.34 PRS_PLINK_0.0199526231496888 FALSE 800.1 Fracture of neck of femur Both 141 1093 18 injuries & poisonings gray50 1093, 141 274, 30 273, 29 273, 37 273, 45 0.19 0.0896 0.0341 1.467 1.21 1.01 1.44 0.00824 0.271 0.976 0.01068 1.01 0.593 1.71 0.199 0.264 0.449 0.3475 1.22 0.728 2.05 0.557 0.262 0.0336 1.474 1.75 1.04 2.92 PRS_PLINK_0.0199526231496888 FALSE 800.2 Fracture of unspecified part of femur Both 184 1491 18 injuries & poisonings gray50 1491, 184 373, 44 373, 44 372, 43 373, 53 0.0779 0.0797 0.328 0.4837 1.08 0.925 1.26 0.07 0.226 0.757 0.1207 1.07 0.688 1.67 -0.00907 0.232 0.969 0.01376 0.991 0.629 1.56 0.333 0.228 0.143 0.8432 1.4 0.893 2.18 PRS_PLINK_0.0199526231496888 FALSE 800.3 Fracture of tibia and fibula Both 221 2393 18 injuries & poisonings gray50 2393, 221 599, 62 598, 63 598, 53 598, 43 -0.13 0.0712 0.0685 1.164 0.878 0.764 1.01 0.0185 0.186 0.921 0.03573 1.02 0.707 1.47 -0.206 0.197 0.294 0.5322 0.813 0.553 1.2 -0.3 0.213 0.158 0.8021 0.741 0.488 1.12 PRS_PLINK_0.0199526231496888 FALSE 800.4 Fracture of patella Both 104 954 18 injuries & poisonings gray50 954, 104 239, 25 238, 28 238, 31 239, 20 -0.0836 0.103 0.417 0.3803 0.92 0.752 1.13 0.0873 0.287 0.761 0.1186 1.09 0.622 1.92 0.209 0.285 0.463 0.3341 1.23 0.705 2.16 -0.0758 0.326 0.816 0.08822 0.927 0.489 1.76 PRS_PLINK_0.0199526231496888 FALSE 801 Fracture of ankle and foot Both 592 6409 18 injuries & poisonings gray50 6409, 592 1603, 156 1602, 150 1602, 150 1602, 136 -0.0316 0.0443 0.476 0.3225 0.969 0.888 1.06 -0.0388 0.12 0.746 0.1274 0.962 0.761 1.22 -0.0284 0.121 0.815 0.08889 0.972 0.767 1.23 -0.129 0.128 0.316 0.5008 0.879 0.684 1.13 PRS_PLINK_0.0199526231496888 FALSE 801.1 Fracture of foot Both 251 3049 18 injuries & poisonings gray50 3049, 251 762, 66 762, 67 762, 65 762, 53 -0.0348 0.0664 0.6 0.2218 0.966 0.848 1.1 0.00444 0.179 0.98 0.008675 1 0.707 1.43 -0.0409 0.182 0.822 0.08519 0.96 0.672 1.37 -0.16 0.197 0.417 0.3801 0.852 0.579 1.25 PRS_PLINK_0.0199526231496888 FALSE 802 Fracture of pelvis Both 113 887 18 injuries & poisonings gray50 887, 113 222, 24 222, 31 221, 23 222, 35 0.167 0.103 0.105 0.9799 1.18 0.966 1.45 0.233 0.284 0.412 0.3856 1.26 0.724 2.2 -0.0206 0.303 0.946 0.02424 0.98 0.541 1.77 0.497 0.292 0.0894 1.048 1.64 0.926 2.92 PRS_PLINK_0.0199526231496888 FALSE 803 Fracture of upper limb Both 544 5400 18 injuries & poisonings gray50 5400, 544 1350, 135 1350, 137 1350, 143 1350, 129 -0.0233 0.0464 0.616 0.2106 0.977 0.892 1.07 0.0202 0.127 0.874 0.05859 1.02 0.795 1.31 0.0335 0.128 0.793 0.1006 1.03 0.805 1.33 -0.0295 0.135 0.827 0.0824 0.971 0.745 1.26 PRS_PLINK_0.0199526231496888 FALSE 803.1 Fracture of humerus Both 179 1775 18 injuries & poisonings gray50 1775, 179 444, 50 444, 31 443, 52 444, 46 0.0209 0.0772 0.786 0.1045 1.02 0.878 1.19 -0.436 0.236 0.0643 1.192 0.646 0.407 1.03 0.032 0.211 0.88 0.05565 1.03 0.682 1.56 -0.04 0.224 0.858 0.06642 0.961 0.62 1.49 PRS_PLINK_0.0199526231496888 FALSE 803.2 Fracture of radius and ulna Both 312 3044 18 injuries & poisonings gray50 3044, 312 761, 84 761, 81 761, 79 761, 68 -0.0628 0.0616 0.308 0.5113 0.939 0.832 1.06 -0.0357 0.163 0.827 0.08262 0.965 0.701 1.33 -0.0612 0.168 0.715 0.1457 0.941 0.677 1.31 -0.221 0.178 0.216 0.6662 0.802 0.565 1.14 PRS_PLINK_0.0199526231496888 FALSE 803.21 Colles' fracture Both 76 746 18 injuries & poisonings gray50 746, 76 187, 22 186, 20 186, 17 187, 17 -0.0926 0.123 0.453 0.3443 0.912 0.716 1.16 -0.0784 0.32 0.807 0.09334 0.925 0.493 1.73 -0.264 0.346 0.446 0.3503 0.768 0.39 1.51 -0.238 0.343 0.488 0.3113 0.788 0.403 1.54 PRS_PLINK_0.0199526231496888 FALSE 803.3 Fracture of clavicle or scapula Both 131 1290 18 injuries & poisonings gray50 1290, 131 323, 33 322, 32 322, 35 323, 31 -0.0498 0.0934 0.594 0.2263 0.951 0.792 1.14 -0.0258 0.256 0.92 0.0363 0.975 0.59 1.61 -0.0173 0.255 0.946 0.02413 0.983 0.597 1.62 -0.173 0.269 0.519 0.2852 0.841 0.497 1.42 PRS_PLINK_0.0199526231496888 FALSE 804 Fracture of hand or wrist Both 457 4343 18 injuries & poisonings gray50 4343, 457 1085, 122 1086, 115 1085, 108 1086, 112 -0.0408 0.0509 0.423 0.3736 0.96 0.869 1.06 -0.0517 0.137 0.706 0.1513 0.95 0.726 1.24 -0.139 0.14 0.324 0.4893 0.871 0.661 1.15 -0.124 0.144 0.389 0.4098 0.883 0.665 1.17 PRS_PLINK_0.0199526231496888 FALSE 805 Fracture of vertebral column without mention of spinal cord injury Both 375 2972 18 injuries & poisonings gray50 2972, 375 743, 93 743, 86 743, 95 743, 101 0.0387 0.0561 0.49 0.31 1.04 0.931 1.16 -0.0842 0.158 0.594 0.2259 0.919 0.674 1.25 0.00894 0.156 0.954 0.02024 1.01 0.742 1.37 0.137 0.159 0.389 0.4096 1.15 0.84 1.57 PRS_PLINK_0.0199526231496888 FALSE 807 Fracture of ribs Both 166 1502 18 injuries & poisonings gray50 1502, 166 376, 38 375, 39 375, 52 376, 37 0.0456 0.0843 0.588 0.2303 1.05 0.887 1.23 0.0715 0.239 0.765 0.1165 1.07 0.672 1.72 0.359 0.227 0.114 0.9419 1.43 0.917 2.24 0.0634 0.252 0.801 0.09631 1.07 0.651 1.74 PRS_PLINK_0.0199526231496888 FALSE 809 Fracture of unspecified bones Both 828 7780 18 injuries & poisonings gray50 7780, 828 1945, 203 1945, 207 1945, 235 1945, 183 0.00747 0.0376 0.842 0.07448 1.01 0.936 1.08 0.0206 0.104 0.844 0.0738 1.02 0.832 1.25 0.137 0.103 0.184 0.7354 1.15 0.937 1.4 -0.0745 0.112 0.505 0.297 0.928 0.746 1.16 PRS_PLINK_0.0199526231496888 FALSE 816 Cerebral laceration and contusion Both 9 132 18 injuries & poisonings gray50 132, 9 33, 3 33, 1 33, 2 33, 3 -0.0289 0.325 0.929 0.03187 0.972 0.514 1.84 -0.689 0.881 0.434 0.3623 0.502 0.0894 2.82 -0.395 0.843 0.639 0.1942 0.674 0.129 3.51 -0.153 0.745 0.837 0.07738 0.858 0.199 3.69 PRS_PLINK_0.0199526231496888 TRUE 817 Concussion Both 332 3057 18 injuries & poisonings gray50 3057, 332 765, 75 764, 86 764, 82 764, 89 0.0591 0.0596 0.322 0.4926 1.06 0.944 1.19 0.147 0.165 0.372 0.4289 1.16 0.838 1.6 0.094 0.17 0.58 0.2368 1.1 0.788 1.53 0.177 0.173 0.307 0.5128 1.19 0.85 1.68 PRS_PLINK_0.0199526231496888 FALSE 818 Intracranial hemorrhage (injury) Both 53 628 18 injuries & poisonings gray50 628, 53 157, 7 157, 14 157, 17 157, 15 0.204 0.142 0.152 0.818 1.23 0.928 1.62 0.685 0.442 0.122 0.915 1.98 0.833 4.72 0.884 0.441 0.0452 1.345 2.42 1.02 5.75 1.03 0.471 0.0293 1.533 2.79 1.11 7.02 PRS_PLINK_0.0199526231496888 FALSE 818.1 Subdural hemorrhage (injury) Both 12 177 18 injuries & poisonings gray50 177, 12 45, 3 44, 1 44, 3 44, 5 0.538 0.34 0.113 0.9462 1.71 0.88 3.33 -1.08 0.997 0.279 0.5541 0.34 0.0481 2.4 -0.0357 0.791 0.964 0.0159 0.965 0.205 4.55 1.08 0.75 0.149 0.8279 2.96 0.679 12.9 PRS_PLINK_0.0199526231496888 TRUE 818.2 Subarachnoid hemorrhage (injury) Both 22 219 18 injuries & poisonings gray50 219, 22 55, 2 55, 6 54, 5 55, 9 0.319 0.216 0.14 0.8531 1.38 0.9 2.1 0.758 0.689 0.271 0.5663 2.13 0.553 8.25 0.886 0.754 0.24 0.6205 2.43 0.554 10.6 1.56 0.721 0.0306 1.514 4.75 1.16 19.5 PRS_PLINK_0.0199526231496888 TRUE 819 Skull and face fracture and other intercranial injury Both 649 6266 18 injuries & poisonings gray50 6266, 649 1567, 148 1566, 159 1566, 172 1567, 170 0.0614 0.0428 0.151 0.8214 1.06 0.978 1.16 0.09 0.12 0.452 0.3452 1.09 0.866 1.38 0.186 0.119 0.12 0.9198 1.2 0.953 1.52 0.184 0.124 0.137 0.8642 1.2 0.943 1.53 PRS_PLINK_0.0199526231496888 FALSE 830 Dislocation Both 988 9764 18 injuries & poisonings gray50 9764, 988 2440, 255 2441, 256 2441, 258 2441, 219 -0.0594 0.0345 0.0856 1.068 0.942 0.881 1.01 0.00297 0.0933 0.975 0.01117 1 0.835 1.2 0.0132 0.0945 0.889 0.05105 1.01 0.842 1.22 -0.18 0.101 0.0749 1.125 0.835 0.685 1.02 PRS_PLINK_0.0199526231496888 FALSE 835 Internal derangement of knee Both 551 6063 18 injuries & poisonings gray50 6063, 551 1515, 141 1516, 144 1515, 137 1516, 129 -0.0468 0.0462 0.311 0.5077 0.954 0.872 1.04 0.0171 0.124 0.89 0.05054 1.02 0.798 1.3 -0.027 0.127 0.832 0.08003 0.973 0.759 1.25 -0.129 0.133 0.333 0.4776 0.879 0.678 1.14 PRS_PLINK_0.0199526231496888 FALSE 836 Traumatic arthropathy Both 116 1170 18 injuries & poisonings gray50 1170, 116 293, 33 292, 29 292, 29 293, 25 -0.0163 0.0942 0.862 0.06425 0.984 0.818 1.18 -0.165 0.265 0.532 0.2737 0.848 0.505 1.42 -0.0939 0.272 0.73 0.1365 0.91 0.534 1.55 -0.208 0.283 0.462 0.3352 0.812 0.466 1.41 PRS_PLINK_0.0199526231496888 FALSE 840 Sprains and strains Both 2059 10465 18 injuries & poisonings gray50 10465, 2059 2616, 560 2616, 538 2616, 498 2616, 463 -0.0713 0.025 0.00435 2.361 0.931 0.887 0.978 -0.0381 0.0672 0.571 0.2434 0.963 0.844 1.1 -0.139 0.0692 0.0447 1.35 0.87 0.76 0.997 -0.205 0.0724 0.00459 2.338 0.815 0.707 0.939 PRS_PLINK_0.0199526231496888 FALSE 840.1 Muscle/tendon sprain Both 108 1152 18 injuries & poisonings gray50 1152, 108 288, 33 288, 25 288, 22 288, 28 -0.0848 0.0996 0.394 0.4041 0.919 0.756 1.12 -0.241 0.276 0.384 0.4162 0.786 0.458 1.35 -0.415 0.285 0.145 0.8393 0.66 0.378 1.15 0.0103 0.281 0.971 0.01286 1.01 0.582 1.75 PRS_PLINK_0.0199526231496888 FALSE 840.2 Rotator cuff (capsule) sprain Both 315 3552 18 injuries & poisonings gray50 3552, 315 888, 91 888, 77 888, 75 888, 72 -0.108 0.059 0.0668 1.175 0.898 0.8 1.01 -0.161 0.161 0.317 0.4989 0.851 0.62 1.17 -0.226 0.163 0.165 0.7819 0.797 0.579 1.1 -0.257 0.17 0.13 0.8873 0.773 0.554 1.08 PRS_PLINK_0.0199526231496888 FALSE 840.3 Joint/ligament sprain Both 805 7704 18 injuries & poisonings gray50 7704, 805 1925, 214 1926, 212 1926, 198 1926, 181 -0.0605 0.0383 0.114 0.9447 0.941 0.873 1.01 -0.00773 0.103 0.94 0.02685 0.992 0.811 1.21 -0.0926 0.106 0.382 0.4174 0.912 0.74 1.12 -0.173 0.112 0.122 0.9119 0.841 0.676 1.05 PRS_PLINK_0.0199526231496888 FALSE 841 Sprains and strains of back and neck Both 462 4757 18 injuries & poisonings gray50 4757, 462 1189, 139 1189, 125 1189, 113 1189, 85 -0.154 0.0502 0.00217 2.663 0.857 0.777 0.946 -0.102 0.13 0.432 0.3644 0.903 0.7 1.17 -0.243 0.135 0.0716 1.145 0.784 0.602 1.02 -0.495 0.15 0.000938 3.028 0.61 0.455 0.817 PRS_PLINK_0.0199526231496888 FALSE 842 Other sprains and strains Both 390 4038 18 injuries & poisonings gray50 4038, 390 1010, 117 1009, 95 1009, 94 1010, 84 -0.142 0.0544 0.00916 2.038 0.868 0.78 0.965 -0.218 0.145 0.133 0.8761 0.804 0.605 1.07 -0.261 0.147 0.0754 1.123 0.77 0.577 1.03 -0.374 0.156 0.0165 1.782 0.688 0.507 0.934 PRS_PLINK_0.0199526231496888 FALSE 850 Hemorrhage or hematoma complicating a procedure Both 613 4984 18 injuries & poisonings gray50 4984, 613 1246, 158 1246, 136 1246, 156 1246, 163 0.0554 0.0441 0.208 0.6816 1.06 0.97 1.15 -0.136 0.124 0.271 0.5674 0.873 0.684 1.11 -0.0223 0.121 0.854 0.06846 0.978 0.771 1.24 0.0451 0.124 0.717 0.1446 1.05 0.82 1.33 PRS_PLINK_0.0199526231496888 FALSE 851 Complications of transplants and reattached limbs Both 820 6522 18 injuries & poisonings gray50 6522, 820 1631, 194 1630, 205 1630, 202 1631, 219 0.101 0.0377 0.00743 2.129 1.11 1.03 1.19 0.0925 0.107 0.387 0.4123 1.1 0.89 1.35 0.0362 0.108 0.737 0.1323 1.04 0.839 1.28 0.169 0.11 0.123 0.9089 1.18 0.955 1.47 PRS_PLINK_0.0199526231496888 FALSE 853 Complication of colostomy or enterostomy Both 147 1083 18 injuries & poisonings gray50 1083, 147 271, 18 271, 47 270, 38 271, 43 0.187 0.0898 0.0376 1.425 1.21 1.01 1.44 0.936 0.283 0.000962 3.017 2.55 1.46 4.44 0.698 0.296 0.0184 1.734 2.01 1.12 3.59 0.703 0.301 0.0195 1.711 2.02 1.12 3.64 PRS_PLINK_0.0199526231496888 FALSE 854 Complications of cardiac/vascular device, implant, and graft Both 671 4438 18 injuries & poisonings gray50 4438, 671 1110, 155 1109, 145 1109, 180 1110, 190 0.11 0.0425 0.00946 2.024 1.12 1.03 1.21 -0.0421 0.124 0.734 0.1346 0.959 0.753 1.22 0.13 0.119 0.274 0.5616 1.14 0.902 1.44 0.241 0.123 0.0491 1.309 1.27 1 1.62 PRS_PLINK_0.0199526231496888 FALSE 855 Complication of nervous system device, implant, and graft Both 72 754 18 injuries & poisonings gray50 754, 72 189, 22 188, 15 188, 12 189, 23 -0.0368 0.124 0.767 0.1154 0.964 0.756 1.23 -0.448 0.342 0.19 0.7202 0.639 0.327 1.25 -0.68 0.372 0.0671 1.173 0.506 0.244 1.05 -0.243 0.337 0.472 0.326 0.785 0.405 1.52 PRS_PLINK_0.0199526231496888 FALSE 856 Vascular complications of surgery and medical procedures Both 75 655 18 injuries & poisonings gray50 655, 75 164, 26 164, 16 163, 12 164, 21 -0.182 0.128 0.154 0.8128 0.834 0.649 1.07 -0.473 0.33 0.152 0.818 0.623 0.326 1.19 -0.763 0.37 0.0391 1.408 0.466 0.226 0.963 -0.204 0.328 0.535 0.2719 0.816 0.429 1.55 PRS_PLINK_0.0199526231496888 FALSE 857 Mechanical complication of unspecified genitourinary device, implant, and graft Both 437 3747 18 injuries & poisonings gray50 3747, 437 937, 117 937, 87 936, 111 937, 122 0.0289 0.0522 0.579 0.2371 1.03 0.929 1.14 -0.251 0.149 0.0933 1.03 0.778 0.581 1.04 -0.113 0.142 0.428 0.3681 0.894 0.676 1.18 0.0603 0.143 0.674 0.1712 1.06 0.802 1.41 PRS_PLINK_0.0199526231496888 FALSE 858 Complication of internal orthopedic device Both 644 5620 18 injuries & poisonings gray50 5620, 644 1405, 147 1405, 152 1405, 187 1405, 158 0.0471 0.043 0.273 0.5636 1.05 0.964 1.14 0.045 0.122 0.713 0.1472 1.05 0.823 1.33 0.242 0.118 0.0403 1.395 1.27 1.01 1.61 0.135 0.126 0.284 0.5471 1.15 0.894 1.47 PRS_PLINK_0.0199526231496888 FALSE 859 Complication due to other implant and internal device Both 666 5472 18 injuries & poisonings gray50 5472, 666 1368, 165 1368, 162 1368, 190 1368, 148 0.00825 0.042 0.844 0.07342 1.01 0.929 1.09 0.0174 0.118 0.882 0.05429 1.02 0.807 1.28 0.125 0.115 0.278 0.5562 1.13 0.904 1.42 -0.0401 0.125 0.748 0.1259 0.961 0.752 1.23 PRS_PLINK_0.0199526231496888 FALSE 860 Bone marrow or stem cell transplant Both 58 442 2 neoplasms darkcyan 442, 58 111, 6 110, 13 110, 15 111, 24 0.442 0.152 0.00359 2.445 1.56 1.16 2.09 0.68 0.487 0.163 0.7889 1.97 0.76 5.12 0.894 0.491 0.0683 1.166 2.45 0.935 6.4 1.28 0.473 0.00677 2.169 3.6 1.42 9.11 PRS_PLINK_0.0199526231496888 FALSE 870 Open wounds of head; neck; and trunk Both 1159 9605 18 injuries & poisonings gray50 9605, 1159 2402, 270 2401, 286 2401, 293 2401, 309 0.0588 0.0321 0.0674 1.172 1.06 0.996 1.13 0.0692 0.09 0.442 0.3544 1.07 0.898 1.28 0.0909 0.0906 0.316 0.5006 1.1 0.917 1.31 0.183 0.0924 0.0479 1.319 1.2 1 1.44 PRS_PLINK_0.0199526231496888 FALSE 870.1 Open wound or laceration of eye or eyelid Both 33 488 18 injuries & poisonings gray50 488, 33 122, 6 122, 7 122, 9 122, 11 0.0769 0.195 0.694 0.1587 1.08 0.736 1.58 0.302 0.52 0.562 0.2501 1.35 0.488 3.75 0.606 0.519 0.243 0.6148 1.83 0.663 5.07 0.828 0.542 0.126 0.8989 2.29 0.792 6.62 PRS_PLINK_0.0199526231496888 TRUE 870.2 Open wound of ear Both 33 351 18 injuries & poisonings gray50 351, 33 88, 8 88, 10 87, 7 88, 8 0.156 0.202 0.44 0.3568 1.17 0.787 1.73 0.285 0.503 0.571 0.2433 1.33 0.496 3.57 0.0915 0.508 0.857 0.06701 1.1 0.405 2.96 0.251 0.557 0.652 0.1856 1.29 0.432 3.83 PRS_PLINK_0.0199526231496888 TRUE 870.3 Other open wound of head and face Both 320 3135 18 injuries & poisonings gray50 3135, 320 784, 90 784, 68 783, 89 784, 73 -0.038 0.0604 0.529 0.2769 0.963 0.855 1.08 -0.273 0.167 0.102 0.9902 0.761 0.548 1.06 -0.0038 0.16 0.981 0.008339 0.996 0.729 1.36 -0.146 0.173 0.397 0.4011 0.864 0.615 1.21 PRS_PLINK_0.0199526231496888 FALSE 870.4 Open wound of nose and sinus Both 45 481 18 injuries & poisonings gray50 481, 45 121, 10 120, 9 120, 13 120, 13 -0.0186 0.156 0.905 0.04321 0.982 0.723 1.33 -0.0213 0.442 0.962 0.01703 0.979 0.412 2.33 0.134 0.434 0.757 0.1206 1.14 0.489 2.68 0.0435 0.44 0.921 0.03555 1.04 0.441 2.48 PRS_PLINK_0.0199526231496888 TRUE 870.5 Open wound of lip and mouth Both 65 652 18 injuries & poisonings gray50 652, 65 163, 17 163, 13 163, 22 163, 13 -0.0216 0.13 0.868 0.06156 0.979 0.758 1.26 -0.335 0.375 0.372 0.4296 0.715 0.343 1.49 0.301 0.343 0.381 0.419 1.35 0.689 2.65 -0.27 0.388 0.486 0.3132 0.763 0.356 1.63 PRS_PLINK_0.0199526231496888 FALSE 870.6 Open wound of neck Both 53 441 18 injuries & poisonings gray50 441, 53 111, 11 110, 11 110, 18 110, 13 0.128 0.145 0.376 0.4245 1.14 0.856 1.51 -0.00674 0.426 0.987 0.005519 0.993 0.431 2.29 0.532 0.399 0.182 0.74 1.7 0.779 3.72 0.128 0.437 0.77 0.1133 1.14 0.483 2.67 PRS_PLINK_0.0199526231496888 FALSE 870.8 Open wound of genital organs Both 75 462 18 injuries & poisonings gray50 462, 75 116, 13 115, 19 115, 22 116, 21 0.188 0.135 0.164 0.7855 1.21 0.926 1.57 0.436 0.385 0.257 0.5895 1.55 0.727 3.29 0.441 0.384 0.251 0.6004 1.55 0.732 3.3 0.526 0.415 0.206 0.6871 1.69 0.75 3.82 PRS_PLINK_0.0199526231496888 FALSE 871 Open wounds of extremities Both 879 8378 18 injuries & poisonings gray50 8378, 879 2095, 217 2094, 226 2094, 211 2095, 225 0.0229 0.0364 0.53 0.2754 1.02 0.953 1.1 0.0442 0.1 0.66 0.1808 1.05 0.859 1.27 -0.0544 0.103 0.597 0.2237 0.947 0.774 1.16 0.0324 0.105 0.757 0.1209 1.03 0.841 1.27 PRS_PLINK_0.0199526231496888 FALSE 871.1 Open wound of hand except finger(s) Both 131 1419 18 injuries & poisonings gray50 1419, 131 355, 32 355, 34 354, 34 355, 31 -0.0131 0.0914 0.886 0.05264 0.987 0.825 1.18 0.0442 0.254 0.862 0.06451 1.05 0.635 1.72 0.0509 0.257 0.843 0.07402 1.05 0.635 1.74 -0.0506 0.264 0.848 0.07145 0.951 0.566 1.6 PRS_PLINK_0.0199526231496888 FALSE 871.2 Open wound of finger(s) Both 247 2548 18 injuries & poisonings gray50 2548, 247 637, 57 637, 74 637, 51 637, 65 -0.0134 0.0685 0.845 0.07337 0.987 0.863 1.13 0.258 0.184 0.161 0.7922 1.29 0.902 1.86 -0.221 0.202 0.274 0.5627 0.801 0.539 1.19 -0.0224 0.198 0.91 0.04091 0.978 0.663 1.44 PRS_PLINK_0.0199526231496888 FALSE 871.3 Open wound of foot except toe(s) alone Both 124 1132 18 injuries & poisonings gray50 1132, 124 283, 29 283, 34 283, 24 283, 37 0.0718 0.0965 0.457 0.3402 1.07 0.889 1.3 0.15 0.263 0.567 0.2462 1.16 0.694 1.95 -0.25 0.286 0.382 0.4177 0.779 0.445 1.36 0.278 0.269 0.302 0.5205 1.32 0.779 2.24 PRS_PLINK_0.0199526231496888 FALSE 871.4 Open wound of toe(s) Both 64 599 18 injuries & poisonings gray50 599, 64 150, 16 150, 10 149, 17 150, 21 0.0475 0.132 0.72 0.1429 1.05 0.809 1.36 -0.299 0.409 0.464 0.3332 0.742 0.333 1.65 0.119 0.361 0.741 0.1302 1.13 0.555 2.29 0.193 0.352 0.583 0.2343 1.21 0.608 2.42 PRS_PLINK_0.0199526231496888 FALSE 872 Traumatic amputation Both 112 1162 18 injuries & poisonings gray50 1162, 112 291, 18 290, 35 290, 33 291, 26 0.197 0.0985 0.0454 1.343 1.22 1 1.48 0.675 0.294 0.0215 1.668 1.96 1.1 3.49 0.642 0.306 0.0358 1.446 1.9 1.04 3.46 0.432 0.327 0.187 0.7282 1.54 0.811 2.92 PRS_PLINK_0.0199526231496888 FALSE 874 Complication of amputation stump Both 42 356 18 injuries & poisonings gray50 356, 42 89, 6 89, 9 89, 15 89, 12 0.387 0.172 0.0244 1.613 1.47 1.05 2.06 0.29 0.5 0.562 0.2501 1.34 0.502 3.56 0.97 0.516 0.06 1.222 2.64 0.96 7.24 0.961 0.547 0.0788 1.103 2.62 0.895 7.64 PRS_PLINK_0.0199526231496888 TRUE 875 Non-healing surgical wound Both 173 1493 18 injuries & poisonings gray50 1493, 173 374, 41 373, 45 373, 43 373, 44 0.036 0.0794 0.651 0.1866 1.04 0.887 1.21 0.0833 0.225 0.712 0.1478 1.09 0.699 1.69 0.0411 0.233 0.86 0.06552 1.04 0.66 1.65 0.151 0.235 0.522 0.2826 1.16 0.733 1.84 PRS_PLINK_0.0199526231496888 FALSE 876 Posttraumatic wound infection not elsewhere classified Both 219 1969 18 injuries & poisonings gray50 1969, 219 493, 42 492, 66 492, 42 492, 68 0.115 0.073 0.115 0.9386 1.12 0.972 1.29 0.448 0.206 0.0298 1.525 1.56 1.04 2.34 0.0112 0.226 0.961 0.01748 1.01 0.65 1.57 0.545 0.213 0.0103 1.986 1.72 1.14 2.62 PRS_PLINK_0.0199526231496888 FALSE 907 Injuries to the nervous system Both 289 2552 18 injuries & poisonings gray50 2552, 289 638, 65 638, 76 638, 70 638, 78 0.0627 0.0649 0.334 0.4765 1.06 0.938 1.21 0.152 0.178 0.393 0.4058 1.16 0.822 1.65 0.0849 0.184 0.644 0.1909 1.09 0.759 1.56 0.164 0.183 0.37 0.4323 1.18 0.823 1.69 PRS_PLINK_0.0199526231496888 FALSE 910 Superficial injury, infected Both 32 322 18 injuries & poisonings gray50 322, 32 81, 6 80, 9 80, 5 81, 12 0.274 0.193 0.156 0.8071 1.32 0.901 1.92 0.419 0.567 0.46 0.3372 1.52 0.5 4.62 -0.153 0.589 0.796 0.09923 0.859 0.271 2.72 0.705 0.55 0.2 0.6998 2.02 0.689 5.94 PRS_PLINK_0.0199526231496888 TRUE 911 Blister Both 79 658 18 injuries & poisonings gray50 658, 79 165, 19 164, 17 164, 21 165, 22 0.113 0.118 0.338 0.471 1.12 0.888 1.41 -0.193 0.346 0.578 0.2379 0.825 0.419 1.63 0.171 0.336 0.611 0.2139 1.19 0.614 2.29 0.13 0.342 0.705 0.1518 1.14 0.582 2.23 PRS_PLINK_0.0199526231496888 FALSE 912 Insect bite Both 141 1339 18 injuries & poisonings gray50 1339, 141 335, 41 335, 34 334, 35 335, 31 -0.119 0.0926 0.199 0.7017 0.888 0.74 1.06 -0.201 0.242 0.407 0.3908 0.818 0.509 1.32 -0.157 0.244 0.521 0.2833 0.855 0.53 1.38 -0.337 0.258 0.191 0.7191 0.714 0.43 1.18 PRS_PLINK_0.0199526231496888 FALSE 913 Toxic effect of venom Both 98 883 18 injuries & poisonings gray50 883, 98 221, 28 221, 21 220, 20 221, 29 -0.0586 0.112 0.602 0.2204 0.943 0.757 1.18 -0.261 0.3 0.385 0.4141 0.77 0.427 1.39 -0.273 0.305 0.371 0.4306 0.761 0.419 1.38 0.111 0.302 0.714 0.1464 1.12 0.618 2.02 PRS_PLINK_0.0199526231496888 FALSE 916 Contusion Both 1142 10465 18 injuries & poisonings gray50 10465, 1142 2616, 268 2616, 291 2616, 294 2616, 289 0.0345 0.0321 0.282 0.5496 1.04 0.972 1.1 0.0819 0.0893 0.359 0.4447 1.09 0.911 1.29 0.111 0.0905 0.221 0.6547 1.12 0.935 1.33 0.0986 0.0936 0.292 0.5346 1.1 0.919 1.33 PRS_PLINK_0.0199526231496888 FALSE 930 Allergic reaction to food Both 277 2408 18 injuries & poisonings gray50 2408, 277 602, 82 602, 67 602, 63 602, 65 -0.0365 0.0651 0.575 0.2405 0.964 0.849 1.1 -0.186 0.175 0.286 0.543 0.83 0.589 1.17 -0.195 0.18 0.277 0.5572 0.823 0.578 1.17 -0.192 0.184 0.295 0.5306 0.825 0.576 1.18 PRS_PLINK_0.0199526231496888 FALSE 931 Contact dermatitis and other eczema due to plants [except food] Both 192 1868 13 dermatologic firebrick 1868, 192 467, 55 467, 53 467, 45 467, 39 -0.116 0.0776 0.134 0.873 0.89 0.765 1.04 -0.00977 0.203 0.962 0.01701 0.99 0.665 1.47 -0.176 0.214 0.41 0.3871 0.838 0.551 1.28 -0.257 0.225 0.253 0.5966 0.773 0.497 1.2 PRS_PLINK_0.0199526231496888 FALSE 938 Dermatitis due to solar radiation Both 1265 7528 13 dermatologic firebrick 7528, 1265 1882, 366 1882, 282 1882, 346 1882, 271 -0.053 0.0316 0.0936 1.029 0.948 0.891 1.01 -0.214 0.0871 0.0142 1.848 0.808 0.681 0.958 -0.0297 0.0844 0.725 0.1399 0.971 0.823 1.15 -0.237 0.0916 0.00958 2.019 0.789 0.659 0.944 PRS_PLINK_0.0199526231496888 FALSE 938.1 Acute dermatitis due to solar radiation Both 52 611 13 dermatologic firebrick 611, 52 153, 11 153, 10 152, 19 153, 12 0.0836 0.149 0.575 0.2403 1.09 0.812 1.46 0.0735 0.431 0.865 0.06316 1.08 0.462 2.51 0.586 0.391 0.134 0.8722 1.8 0.835 3.86 0.0575 0.425 0.893 0.04937 1.06 0.46 2.44 PRS_PLINK_0.0199526231496888 FALSE 938.2 Chronic dermatitis due to solar radiation Both 1183 7353 13 dermatologic firebrick 7353, 1183 1839, 345 1838, 265 1838, 323 1838, 250 -0.0577 0.0325 0.076 1.119 0.944 0.886 1.01 -0.22 0.0894 0.014 1.854 0.803 0.674 0.956 -0.0511 0.0868 0.556 0.2549 0.95 0.802 1.13 -0.254 0.0944 0.00712 2.147 0.776 0.645 0.933 PRS_PLINK_0.0199526231496888 FALSE 939 Atopic/contact dermatitis due to other or unspecified Both 1938 8765 13 dermatologic firebrick 8765, 1938 2192, 525 2191, 482 2191, 498 2191, 433 -0.022 0.0263 0.402 0.3956 0.978 0.929 1.03 -0.053 0.0712 0.456 0.341 0.948 0.825 1.09 -0.0103 0.0719 0.886 0.05265 0.99 0.86 1.14 -0.124 0.0761 0.103 0.9891 0.883 0.761 1.03 PRS_PLINK_0.0199526231496888 FALSE 939.1 Contact and allergic dermatitis of eyelid Both 26 239 13 dermatologic firebrick 239, 26 60, 3 60, 8 59, 8 60, 7 0.202 0.211 0.339 0.4696 1.22 0.809 1.85 0.693 0.629 0.271 0.5671 2 0.582 6.86 0.871 0.64 0.173 0.7615 2.39 0.682 8.37 0.465 0.652 0.476 0.3225 1.59 0.443 5.72 PRS_PLINK_0.0199526231496888 TRUE 941 Adverse reaction to serum or vaccine Both 47 490 18 injuries & poisonings gray50 490, 47 123, 9 122, 10 122, 12 123, 16 0.193 0.157 0.22 0.6575 1.21 0.891 1.65 0.111 0.45 0.805 0.09444 1.12 0.462 2.7 0.34 0.445 0.444 0.3523 1.41 0.588 3.36 0.238 0.454 0.6 0.2216 1.27 0.521 3.09 PRS_PLINK_0.0199526231496888 TRUE 942 Infusion and transfusion reaction Both 99 766 18 injuries & poisonings gray50 766, 99 192, 22 191, 31 191, 21 192, 25 0.0762 0.106 0.473 0.3251 1.08 0.876 1.33 0.316 0.294 0.283 0.5486 1.37 0.771 2.44 -0.0977 0.327 0.765 0.1163 0.907 0.478 1.72 0.153 0.331 0.643 0.192 1.17 0.61 2.23 PRS_PLINK_0.0199526231496888 FALSE 946 Anaphylactic shock NOS Both 148 1457 18 injuries & poisonings gray50 1457, 148 365, 42 364, 47 364, 28 364, 31 -0.141 0.0856 0.0997 1.001 0.869 0.735 1.03 0.103 0.225 0.646 0.1895 1.11 0.713 1.72 -0.403 0.255 0.114 0.9415 0.668 0.405 1.1 -0.327 0.252 0.195 0.7106 0.721 0.44 1.18 PRS_PLINK_0.0199526231496888 FALSE 947 Urticaria Both 384 3647 13 dermatologic firebrick 3647, 384 912, 110 912, 92 911, 101 912, 81 -0.0843 0.0559 0.132 0.8809 0.919 0.824 1.03 -0.18 0.149 0.227 0.6449 0.835 0.624 1.12 -0.0944 0.149 0.526 0.2793 0.91 0.68 1.22 -0.295 0.161 0.066 1.181 0.744 0.543 1.02 PRS_PLINK_0.0199526231496888 FALSE 949 Allergies, other Both 2132 8750 18 injuries & poisonings gray50 8750, 2132 2188, 560 2187, 531 2187, 523 2188, 517 0.0019 0.0251 0.94 0.02696 1 0.954 1.05 -0.0356 0.0691 0.607 0.2167 0.965 0.843 1.11 -0.0319 0.0703 0.65 0.1873 0.969 0.844 1.11 -0.0325 0.0724 0.654 0.1844 0.968 0.84 1.12 PRS_PLINK_0.0199526231496888 FALSE 952 Spinal cord injury without evidence of spinal bone injury Both 152 1178 18 injuries & poisonings gray50 1178, 152 295, 33 294, 42 294, 34 295, 43 0.0159 0.0888 0.858 0.06653 1.02 0.854 1.21 0.236 0.247 0.339 0.4695 1.27 0.78 2.06 -0.0638 0.263 0.808 0.09254 0.938 0.561 1.57 0.317 0.256 0.216 0.6666 1.37 0.831 2.27 PRS_PLINK_0.0199526231496888 FALSE 957 Injury to other and unspecified nerves Both 31 354 18 injuries & poisonings gray50 354, 31 89, 9 88, 10 88, 4 89, 8 -0.14 0.178 0.432 0.3647 0.869 0.613 1.23 0.121 0.46 0.792 0.1014 1.13 0.459 2.78 -0.738 0.559 0.187 0.7282 0.478 0.16 1.43 -0.331 0.487 0.497 0.304 0.718 0.276 1.87 PRS_PLINK_0.0199526231496888 TRUE 958 Certain early complications of trauma or procedure Both 410 3075 18 injuries & poisonings gray50 3075, 410 769, 97 769, 98 768, 114 769, 101 0.0536 0.0537 0.319 0.4965 1.06 0.95 1.17 0.0255 0.152 0.867 0.06213 1.03 0.762 1.38 0.202 0.149 0.177 0.753 1.22 0.913 1.64 0.0952 0.157 0.545 0.2633 1.1 0.808 1.5 PRS_PLINK_0.0199526231496888 FALSE 958.1 Postoperative shock Both 87 393 18 injuries & poisonings gray50 393, 87 99, 21 98, 22 98, 17 98, 27 0.218 0.127 0.0848 1.072 1.24 0.971 1.59 0.0897 0.334 0.788 0.1034 1.09 0.569 2.1 -0.177 0.36 0.624 0.2047 0.838 0.414 1.7 0.373 0.349 0.285 0.5451 1.45 0.733 2.88 PRS_PLINK_0.0199526231496888 FALSE 958.2 Traumatic and surgical subcutaneous emphysema Both 38 264 18 injuries & poisonings gray50 264, 38 66, 15 66, 6 66, 9 66, 8 -0.216 0.181 0.234 0.6304 0.806 0.565 1.15 -0.859 0.502 0.0869 1.061 0.424 0.159 1.13 -0.397 0.476 0.404 0.3937 0.672 0.264 1.71 -0.488 0.493 0.322 0.4915 0.614 0.234 1.61 PRS_PLINK_0.0199526231496888 TRUE 960 Poisoning by antibiotics Both 794 5812 18 injuries & poisonings gray50 5812, 794 1452, 213 1453, 174 1453, 200 1453, 207 0.0584 0.0388 0.132 0.8785 1.06 0.983 1.14 -0.214 0.109 0.05 1.301 0.807 0.651 1 -0.0574 0.107 0.591 0.2282 0.944 0.766 1.16 -0.0264 0.109 0.808 0.09242 0.974 0.787 1.21 PRS_PLINK_0.0199526231496888 FALSE 960.1 Adverse effects of antibacterials (not penicillins) Both 103 876 18 injuries & poisonings gray50 876, 103 219, 34 219, 20 219, 24 219, 25 -0.0448 0.106 0.674 0.1713 0.956 0.776 1.18 -0.441 0.296 0.136 0.8661 0.643 0.36 1.15 -0.306 0.284 0.282 0.5496 0.737 0.422 1.29 -0.304 0.287 0.29 0.5375 0.738 0.421 1.3 PRS_PLINK_0.0199526231496888 FALSE 960.2 Allergy/adverse effect of penicillin Both 541 4125 18 injuries & poisonings gray50 4125, 541 1032, 155 1031, 119 1031, 131 1031, 136 0.00871 0.0469 0.853 0.06922 1.01 0.92 1.11 -0.279 0.13 0.0321 1.494 0.756 0.586 0.976 -0.167 0.128 0.193 0.7139 0.847 0.659 1.09 -0.138 0.13 0.287 0.5419 0.871 0.675 1.12 PRS_PLINK_0.0199526231496888 FALSE 961 Poisoning by other anti-infectives Both 168 1369 18 injuries & poisonings gray50 1369, 168 343, 36 342, 29 342, 59 342, 44 0.122 0.0833 0.144 0.8406 1.13 0.959 1.33 -0.238 0.258 0.355 0.4497 0.788 0.475 1.31 0.524 0.228 0.0212 1.673 1.69 1.08 2.64 0.2 0.248 0.421 0.3755 1.22 0.751 1.99 PRS_PLINK_0.0199526231496888 FALSE 961.1 Poisoning/allergy of sulfonamides Both 301 2674 18 injuries & poisonings gray50 2674, 301 669, 71 668, 71 668, 75 669, 84 0.0897 0.0631 0.155 0.8103 1.09 0.967 1.24 -0.0107 0.176 0.951 0.02172 0.989 0.701 1.4 0.073 0.176 0.679 0.168 1.08 0.761 1.52 0.13 0.179 0.466 0.3316 1.14 0.803 1.62 PRS_PLINK_0.0199526231496888 FALSE 962 Poisoning by hormones and synthetic substitutes Both 216 1964 18 injuries & poisonings gray50 1964, 216 491, 54 491, 43 491, 57 491, 62 0.16 0.0743 0.0315 1.502 1.17 1.01 1.36 -0.214 0.213 0.317 0.4989 0.808 0.532 1.23 0.0459 0.203 0.821 0.08573 1.05 0.704 1.56 0.175 0.205 0.394 0.4048 1.19 0.797 1.78 PRS_PLINK_0.0199526231496888 FALSE 962.1 Adrenal cortical steroids causing adverse effects in therapeutic use Both 115 916 18 injuries & poisonings gray50 916, 115 229, 23 229, 24 229, 33 229, 35 0.308 0.107 0.004 2.398 1.36 1.1 1.68 0.06 0.302 0.843 0.07439 1.06 0.587 1.92 0.303 0.291 0.298 0.5263 1.35 0.765 2.4 0.547 0.296 0.0642 1.192 1.73 0.968 3.09 PRS_PLINK_0.0199526231496888 FALSE 962.2 Insulins and antidiabetic agents causing adverse effects in therapeutic use Both 9 158 18 injuries & poisonings gray50 158, 9 40, 1 39, 1 39, 3 40, 4 0.272 0.301 0.365 0.4372 1.31 0.728 2.37 -0.0291 0.996 0.977 0.01026 0.971 0.138 6.84 0.833 0.885 0.346 0.4603 2.3 0.406 13 0.871 0.857 0.31 0.5091 2.39 0.445 12.8 PRS_PLINK_0.0199526231496888 TRUE 962.3 Hormones and synthetic substitutes causing adverse effects in therapeutic use Both 125 1161 18 injuries & poisonings gray50 1161, 125 291, 35 290, 26 290, 31 290, 33 0.0663 0.0989 0.503 0.2987 1.07 0.88 1.3 -0.276 0.269 0.305 0.5161 0.759 0.447 1.29 -0.118 0.26 0.65 0.1872 0.889 0.534 1.48 -0.108 0.265 0.685 0.1641 0.898 0.534 1.51 PRS_PLINK_0.0199526231496888 FALSE 963 Poisoning by primarily systemic agents Both 750 6135 18 injuries & poisonings gray50 6135, 750 1533, 191 1534, 187 1533, 210 1534, 162 -0.0349 0.0397 0.38 0.4204 0.966 0.893 1.04 -0.00878 0.109 0.936 0.02868 0.991 0.8 1.23 0.0797 0.109 0.463 0.3346 1.08 0.875 1.34 -0.121 0.118 0.305 0.5152 0.886 0.704 1.12 PRS_PLINK_0.0199526231496888 FALSE 963.1 Antineoplastic and immunosuppressive drugs causing adverse effects Both 735 6014 18 injuries & poisonings gray50 6014, 735 1503, 189 1503, 183 1503, 209 1504, 154 -0.0468 0.0401 0.244 0.6135 0.954 0.882 1.03 -0.0204 0.11 0.853 0.06904 0.98 0.789 1.22 0.0861 0.109 0.43 0.3669 1.09 0.88 1.35 -0.158 0.119 0.185 0.732 0.854 0.676 1.08 PRS_PLINK_0.0199526231496888 FALSE 964 Poisoning by agents primarily affecting blood constituents Both 245 1509 18 injuries & poisonings gray50 1509, 245 378, 46 377, 50 377, 70 377, 79 0.289 0.0738 8.74e-05 4.059 1.34 1.16 1.54 0.105 0.218 0.629 0.201 1.11 0.724 1.7 0.384 0.206 0.0615 1.211 1.47 0.982 2.2 0.674 0.21 0.00135 2.871 1.96 1.3 2.96 PRS_PLINK_0.0199526231496888 FALSE 964.1 Anticoagulants causing adverse effects Both 235 1444 18 injuries & poisonings gray50 1444, 235 361, 43 361, 43 361, 72 361, 77 0.309 0.0749 3.66e-05 4.437 1.36 1.18 1.58 0.0137 0.23 0.953 0.02109 1.01 0.646 1.59 0.482 0.21 0.0216 1.667 1.62 1.07 2.44 0.702 0.215 0.00112 2.949 2.02 1.32 3.08 PRS_PLINK_0.0199526231496888 FALSE 965 Poisoning by analgesics, antipyretics, and antirheumatics Both 291 2282 18 injuries & poisonings gray50 2282, 291 571, 60 570, 69 570, 88 571, 74 0.13 0.0634 0.0403 1.395 1.14 1.01 1.29 0.13 0.185 0.484 0.3148 1.14 0.792 1.64 0.371 0.179 0.0381 1.419 1.45 1.02 2.06 0.12 0.19 0.528 0.2775 1.13 0.777 1.63 PRS_PLINK_0.0199526231496888 FALSE 965.1 Opiates and related narcotics causing adverse effects in therapeutic use Both 480 3747 18 injuries & poisonings gray50 3747, 480 937, 136 937, 94 936, 116 937, 134 0.0326 0.0492 0.508 0.2945 1.03 0.938 1.14 -0.386 0.142 0.00664 2.178 0.68 0.514 0.898 -0.19 0.137 0.165 0.782 0.827 0.633 1.08 -0.0333 0.136 0.807 0.09336 0.967 0.741 1.26 PRS_PLINK_0.0199526231496888 FALSE 965.3 Salicylates causing adverse effects in therapeutic use Both 28 295 18 injuries & poisonings gray50 295, 28 74, 7 74, 6 73, 5 74, 10 0.132 0.192 0.49 0.3096 1.14 0.784 1.66 -0.047 0.584 0.936 0.02879 0.954 0.303 3 -0.331 0.616 0.591 0.2284 0.718 0.215 2.4 -0.056 0.575 0.922 0.03508 0.946 0.306 2.92 PRS_PLINK_0.0199526231496888 TRUE 966 Poisoning by anticonvulsants and anti-Parkinsonism drugs Both 39 269 18 injuries & poisonings gray50 269, 39 68, 10 67, 8 67, 5 67, 16 0.126 0.177 0.477 0.3217 1.13 0.802 1.6 -0.194 0.483 0.688 0.1626 0.823 0.319 2.12 -0.754 0.554 0.173 0.7611 0.47 0.159 1.39 0.297 0.455 0.514 0.2893 1.35 0.552 3.28 PRS_PLINK_0.0199526231496888 TRUE 967 Adverse effects of sedatives or other central nervous system depressants and anesthetics Both 359 3450 18 injuries & poisonings gray50 3450, 359 862, 96 862, 73 862, 100 863, 90 -0.0303 0.0553 0.584 0.2338 0.97 0.87 1.08 -0.291 0.162 0.0726 1.139 0.748 0.544 1.03 0.0471 0.152 0.756 0.1213 1.05 0.778 1.41 -0.14 0.162 0.385 0.4143 0.869 0.633 1.19 PRS_PLINK_0.0199526231496888 FALSE 969 Poisoning by psychotropic agents Both 93 852 18 injuries & poisonings gray50 852, 93 213, 23 213, 20 213, 24 213, 26 0.0574 0.112 0.608 0.2158 1.06 0.85 1.32 -0.134 0.317 0.672 0.1725 0.874 0.469 1.63 0.149 0.304 0.624 0.2046 1.16 0.64 2.1 0.148 0.308 0.631 0.1998 1.16 0.634 2.12 PRS_PLINK_0.0199526231496888 FALSE 971 Poisoning by drugs primarily affecting the autonomic nervous system Both 19 135 18 injuries & poisonings gray50 135, 19 34, 7 34, 4 33, 2 34, 6 -0.22 0.239 0.356 0.448 0.803 0.503 1.28 -0.407 0.679 0.549 0.2602 0.666 0.176 2.52 -0.895 0.791 0.258 0.5887 0.408 0.0866 1.93 -0.299 0.625 0.633 0.1989 0.742 0.218 2.52 PRS_PLINK_0.0199526231496888 TRUE 972 Poisoning by agents primarily affecting the cardiovascular system Both 97 549 18 injuries & poisonings gray50 549, 97 138, 15 137, 17 137, 30 137, 35 0.444 0.12 0.000221 3.657 1.56 1.23 1.97 0.194 0.379 0.608 0.2163 1.21 0.578 2.55 0.771 0.342 0.0244 1.613 2.16 1.1 4.23 1.03 0.35 0.00324 2.49 2.8 1.41 5.56 PRS_PLINK_0.0199526231496888 FALSE 972.1 Cardiac rhythm regulators causing adverse effects in therapeutic use Both 38 118 18 injuries & poisonings gray50 118, 38 30, 8 29, 10 29, 9 30, 11 0.278 0.219 0.204 0.6904 1.32 0.86 2.03 0.5 0.611 0.413 0.3835 1.65 0.498 5.46 0.241 0.563 0.669 0.1747 1.27 0.422 3.84 0.454 0.647 0.482 0.3166 1.58 0.443 5.6 PRS_PLINK_0.0199526231496888 TRUE 972.6 Antihypertensive agents causing adverse effects Both 29 186 18 injuries & poisonings gray50 186, 29 47, 5 46, 8 46, 7 47, 9 0.309 0.216 0.154 0.8138 1.36 0.891 2.08 0.614 0.662 0.354 0.4514 1.85 0.505 6.76 0.357 0.643 0.579 0.2375 1.43 0.405 5.04 0.974 0.623 0.118 0.9277 2.65 0.781 8.99 PRS_PLINK_0.0199526231496888 TRUE 974 Poisoning by water, mineral, and uric acid metabolism drugs Both 41 217 18 injuries & poisonings gray50 217, 41 55, 7 54, 8 54, 8 54, 18 0.359 0.174 0.0387 1.412 1.43 1.02 2.01 0.192 0.533 0.719 0.1435 1.21 0.426 3.45 0.351 0.551 0.524 0.2804 1.42 0.482 4.18 0.844 0.5 0.0914 1.039 2.33 0.873 6.2 PRS_PLINK_0.0199526231496888 TRUE 975 Poisoning by agents primarily acting on the smooth and skeletal muscles and respiratory system Both 26 224 18 injuries & poisonings gray50 224, 26 56, 6 56, 7 56, 5 56, 8 0.029 0.202 0.886 0.05258 1.03 0.693 1.53 -0.0158 0.566 0.978 0.009768 0.984 0.325 2.98 -0.182 0.62 0.769 0.1142 0.834 0.248 2.81 0.0189 0.606 0.975 0.01096 1.02 0.311 3.34 PRS_PLINK_0.0199526231496888 TRUE 976 Poisoning by agents primarily affecting skin & mucous membrane, ophthalmological, otorhinolaryngological, & dental drugs Both 19 158 18 injuries & poisonings gray50 158, 19 40, 2 39, 7 39, 2 40, 8 0.293 0.233 0.208 0.6813 1.34 0.849 2.12 0.893 0.745 0.23 0.6375 2.44 0.567 10.5 -0.63 0.989 0.524 0.2809 0.532 0.0767 3.7 1.36 0.733 0.064 1.194 3.88 0.924 16.3 PRS_PLINK_0.0199526231496888 TRUE 977 Personal history of allergy to medicinal agents Both 522 4285 18 injuries & poisonings gray50 4285, 522 1072, 119 1071, 132 1071, 142 1071, 129 0.0671 0.048 0.162 0.7906 1.07 0.973 1.17 0.0914 0.134 0.494 0.3061 1.1 0.843 1.42 0.201 0.133 0.132 0.8808 1.22 0.941 1.59 0.0984 0.14 0.483 0.3164 1.1 0.838 1.45 PRS_PLINK_0.0199526231496888 FALSE 979 Adverse drug events and drug allergies Both 1003 8340 18 injuries & poisonings gray50 8340, 1003 2084, 277 2085, 224 2085, 254 2085, 248 0.0102 0.0343 0.766 0.116 1.01 0.945 1.08 -0.204 0.0956 0.0325 1.488 0.815 0.676 0.983 -0.0856 0.0939 0.362 0.441 0.918 0.764 1.1 -0.118 0.0972 0.224 0.6498 0.889 0.734 1.07 PRS_PLINK_0.0199526231496888 FALSE 980 Encounter for long-term (current) use of antibiotics Both 353 3149 1 infectious diseases blue 3149, 353 788, 85 787, 99 787, 79 787, 90 -0.0171 0.0565 0.762 0.118 0.983 0.88 1.1 0.153 0.156 0.327 0.4849 1.16 0.858 1.58 -0.104 0.166 0.532 0.2737 0.902 0.651 1.25 0.0307 0.167 0.854 0.06874 1.03 0.744 1.43 PRS_PLINK_0.0199526231496888 FALSE 985 Toxic effect of other metals Both 14 125 18 injuries & poisonings gray50 125, 14 32, 3 31, 2 31, 6 31, 3 0.083 0.294 0.778 0.1092 1.09 0.611 1.93 0.749 1.03 0.468 0.33 2.11 0.28 15.9 0.566 0.749 0.45 0.347 1.76 0.406 7.64 0.518 0.881 0.556 0.2547 1.68 0.299 9.43 PRS_PLINK_0.0199526231496888 TRUE 989 Toxic effect of other substances, chiefly nonmedicinal as to source Both 47 368 18 injuries & poisonings gray50 368, 47 92, 10 92, 9 92, 13 92, 15 0.0778 0.163 0.633 0.1985 1.08 0.785 1.49 -0.00925 0.458 0.984 0.007049 0.991 0.404 2.43 0.273 0.452 0.546 0.2629 1.31 0.542 3.18 0.0947 0.443 0.831 0.08058 1.1 0.462 2.62 PRS_PLINK_0.0199526231496888 TRUE 990 Effects radiation NOS Both 1060 7180 18 injuries & poisonings gray50 7180, 1060 1795, 263 1795, 264 1795, 258 1795, 275 0.0324 0.0338 0.339 0.4701 1.03 0.967 1.1 0.0264 0.0942 0.78 0.1082 1.03 0.854 1.23 -0.0298 0.0956 0.755 0.122 0.971 0.805 1.17 -0.00433 0.0968 0.964 0.01577 0.996 0.824 1.2 PRS_PLINK_0.0199526231496888 FALSE 994 Sepsis and SIRS Both 759 4849 18 injuries & poisonings gray50 4849, 759 1213, 171 1212, 180 1212, 197 1212, 210 0.108 0.0399 0.00656 2.183 1.11 1.03 1.21 0.0697 0.115 0.543 0.2649 1.07 0.856 1.34 0.133 0.114 0.242 0.6163 1.14 0.914 1.43 0.208 0.116 0.0729 1.137 1.23 0.981 1.54 PRS_PLINK_0.0199526231496888 FALSE 994.1 Systemic inflammatory response syndrome (SIRS) Both 115 720 18 injuries & poisonings gray50 720, 115 180, 28 180, 24 180, 32 180, 31 0.108 0.102 0.29 0.5372 1.11 0.912 1.36 -0.188 0.293 0.523 0.2817 0.829 0.466 1.47 0.13 0.285 0.649 0.188 1.14 0.651 1.99 0.115 0.292 0.695 0.1582 1.12 0.632 1.99 PRS_PLINK_0.0199526231496888 FALSE 994.2 Sepsis Both 717 4568 18 injuries & poisonings gray50 4568, 717 1142, 160 1142, 173 1142, 186 1142, 197 0.103 0.0409 0.0119 1.926 1.11 1.02 1.2 0.0984 0.118 0.403 0.3944 1.1 0.876 1.39 0.132 0.117 0.261 0.583 1.14 0.907 1.44 0.207 0.12 0.0841 1.075 1.23 0.973 1.55 PRS_PLINK_0.0199526231496888 FALSE 994.21 Septic shock Both 291 1336 18 injuries & poisonings gray50 1336, 291 334, 44 334, 72 334, 75 334, 100 0.297 0.0658 6.51e-06 5.187 1.35 1.18 1.53 0.487 0.206 0.0182 1.74 1.63 1.09 2.44 0.547 0.208 0.0087 2.06 1.73 1.15 2.6 0.825 0.204 5.24e-05 4.28 2.28 1.53 3.4 PRS_PLINK_0.0199526231496888 FALSE